data_9D3V
# 
_entry.id   9D3V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9D3V         pdb_00009d3v 10.2210/pdb9d3v/pdb 
WWPDB D_1000287272 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-05 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9D3V 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jeff.bell@schrodinger.com 
_pdbx_contact_author.name_first         Jeffrey 
_pdbx_contact_author.name_last          Bell 
_pdbx_contact_author.name_mi            A. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8310-0183 
# 
_audit_author.name               'Bell, J.A.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0002-8310-0183 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            67 
_citation.language                  ? 
_citation.page_first                21811 
_citation.page_last                 21840 
_citation.title                     
;Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an In Silico Enabled Drug Discovery Platform.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.4c01405 
_citation.pdbx_database_id_PubMed   39666597 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Igawa, H.'            1  0009-0007-3802-6344 
primary 'Konst, Z.A.'          2  ?                   
primary 'Therrien, E.'         3  0000-0003-3306-9162 
primary 'Shelley, M.'          4  ?                   
primary 'Koldso, H.'           5  ?                   
primary 'Bos, P.H.'            6  0000-0002-8710-4771 
primary 'Negri, A.'            7  0000-0003-0726-7608 
primary 'Verras, A.'           8  ?                   
primary 'Guo, J.'              9  ?                   
primary 'Dahlgren, M.K.'       10 ?                   
primary 'Levinson, A.'         11 ?                   
primary 'Parr, B.T.'           12 ?                   
primary 'Kurhade, S.E.'        13 ?                   
primary 'Latthe, P.'           14 ?                   
primary 'Shetty, R.'           15 ?                   
primary 'Santhanakrishnan, S.' 16 ?                   
primary 'Amberg-Johnson, K.'   17 ?                   
primary 'Futran, A.S.'         18 ?                   
primary 'Atsriku, C.'          19 ?                   
primary 'Pelletier, R.D.'      20 0000-0003-2112-1461 
primary 'Liu, Z.'              21 ?                   
primary 'Bell, J.A.'           22 0000-0002-8310-0183 
primary 'Bhat, S.'             23 0000-0003-1819-5726 
primary 'Svensson, M.'         24 ?                   
primary 'Gerasyuto, A.I.'      25 0009-0001-2696-7207 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Epidermal growth factor receptor'                                                                             
37463.348 1  2.7.10.1 'T790M, C797S, L858R, E865A, E866A, K867A' 'kinase domain' ? 
2 non-polymer syn '(4S)-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-methyl-1-(propan-2-yl)-1H-imidazo[1,2-b]pyrazol-6-amine' 
369.464   1  ?        ?                                          ?               ? 
3 non-polymer syn 'CHLORIDE ION'                                                                                                 
35.453    4  ?        ?                                          ?               ? 
4 water       nat water                                                                                                          
18.015    35 ?        ?                                          ?               ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GSMGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNP
HVCRLLGICLTSTVQLIMQLMPFGSLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK
ITDFGRAKLLGAAAAEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGER
LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVD
ADEYLIPQQG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GSMGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNP
HVCRLLGICLTSTVQLIMQLMPFGSLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK
ITDFGRAKLLGAAAAEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGER
LPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVD
ADEYLIPQQG
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(4S)-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-methyl-1-(propan-2-yl)-1H-imidazo[1,2-b]pyrazol-6-amine' A1A5V 
3 'CHLORIDE ION'                                                                                                 CL    
4 water                                                                                                          HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   MET n 
1 4   GLY n 
1 5   GLU n 
1 6   ALA n 
1 7   PRO n 
1 8   ASN n 
1 9   GLN n 
1 10  ALA n 
1 11  LEU n 
1 12  LEU n 
1 13  ARG n 
1 14  ILE n 
1 15  LEU n 
1 16  LYS n 
1 17  GLU n 
1 18  THR n 
1 19  GLU n 
1 20  PHE n 
1 21  LYS n 
1 22  LYS n 
1 23  ILE n 
1 24  LYS n 
1 25  VAL n 
1 26  LEU n 
1 27  GLY n 
1 28  SER n 
1 29  GLY n 
1 30  ALA n 
1 31  PHE n 
1 32  GLY n 
1 33  THR n 
1 34  VAL n 
1 35  TYR n 
1 36  LYS n 
1 37  GLY n 
1 38  LEU n 
1 39  TRP n 
1 40  ILE n 
1 41  PRO n 
1 42  GLU n 
1 43  GLY n 
1 44  GLU n 
1 45  LYS n 
1 46  VAL n 
1 47  LYS n 
1 48  ILE n 
1 49  PRO n 
1 50  VAL n 
1 51  ALA n 
1 52  ILE n 
1 53  LYS n 
1 54  GLU n 
1 55  LEU n 
1 56  ARG n 
1 57  GLU n 
1 58  ALA n 
1 59  THR n 
1 60  SER n 
1 61  PRO n 
1 62  LYS n 
1 63  ALA n 
1 64  ASN n 
1 65  LYS n 
1 66  GLU n 
1 67  ILE n 
1 68  LEU n 
1 69  ASP n 
1 70  GLU n 
1 71  ALA n 
1 72  TYR n 
1 73  VAL n 
1 74  MET n 
1 75  ALA n 
1 76  SER n 
1 77  VAL n 
1 78  ASP n 
1 79  ASN n 
1 80  PRO n 
1 81  HIS n 
1 82  VAL n 
1 83  CYS n 
1 84  ARG n 
1 85  LEU n 
1 86  LEU n 
1 87  GLY n 
1 88  ILE n 
1 89  CYS n 
1 90  LEU n 
1 91  THR n 
1 92  SER n 
1 93  THR n 
1 94  VAL n 
1 95  GLN n 
1 96  LEU n 
1 97  ILE n 
1 98  MET n 
1 99  GLN n 
1 100 LEU n 
1 101 MET n 
1 102 PRO n 
1 103 PHE n 
1 104 GLY n 
1 105 SER n 
1 106 LEU n 
1 107 LEU n 
1 108 ASP n 
1 109 TYR n 
1 110 VAL n 
1 111 ARG n 
1 112 GLU n 
1 113 HIS n 
1 114 LYS n 
1 115 ASP n 
1 116 ASN n 
1 117 ILE n 
1 118 GLY n 
1 119 SER n 
1 120 GLN n 
1 121 TYR n 
1 122 LEU n 
1 123 LEU n 
1 124 ASN n 
1 125 TRP n 
1 126 CYS n 
1 127 VAL n 
1 128 GLN n 
1 129 ILE n 
1 130 ALA n 
1 131 LYS n 
1 132 GLY n 
1 133 MET n 
1 134 ASN n 
1 135 TYR n 
1 136 LEU n 
1 137 GLU n 
1 138 ASP n 
1 139 ARG n 
1 140 ARG n 
1 141 LEU n 
1 142 VAL n 
1 143 HIS n 
1 144 ARG n 
1 145 ASP n 
1 146 LEU n 
1 147 ALA n 
1 148 ALA n 
1 149 ARG n 
1 150 ASN n 
1 151 VAL n 
1 152 LEU n 
1 153 VAL n 
1 154 LYS n 
1 155 THR n 
1 156 PRO n 
1 157 GLN n 
1 158 HIS n 
1 159 VAL n 
1 160 LYS n 
1 161 ILE n 
1 162 THR n 
1 163 ASP n 
1 164 PHE n 
1 165 GLY n 
1 166 ARG n 
1 167 ALA n 
1 168 LYS n 
1 169 LEU n 
1 170 LEU n 
1 171 GLY n 
1 172 ALA n 
1 173 ALA n 
1 174 ALA n 
1 175 ALA n 
1 176 GLU n 
1 177 TYR n 
1 178 HIS n 
1 179 ALA n 
1 180 GLU n 
1 181 GLY n 
1 182 GLY n 
1 183 LYS n 
1 184 VAL n 
1 185 PRO n 
1 186 ILE n 
1 187 LYS n 
1 188 TRP n 
1 189 MET n 
1 190 ALA n 
1 191 LEU n 
1 192 GLU n 
1 193 SER n 
1 194 ILE n 
1 195 LEU n 
1 196 HIS n 
1 197 ARG n 
1 198 ILE n 
1 199 TYR n 
1 200 THR n 
1 201 HIS n 
1 202 GLN n 
1 203 SER n 
1 204 ASP n 
1 205 VAL n 
1 206 TRP n 
1 207 SER n 
1 208 TYR n 
1 209 GLY n 
1 210 VAL n 
1 211 THR n 
1 212 VAL n 
1 213 TRP n 
1 214 GLU n 
1 215 LEU n 
1 216 MET n 
1 217 THR n 
1 218 PHE n 
1 219 GLY n 
1 220 SER n 
1 221 LYS n 
1 222 PRO n 
1 223 TYR n 
1 224 ASP n 
1 225 GLY n 
1 226 ILE n 
1 227 PRO n 
1 228 ALA n 
1 229 SER n 
1 230 GLU n 
1 231 ILE n 
1 232 SER n 
1 233 SER n 
1 234 ILE n 
1 235 LEU n 
1 236 GLU n 
1 237 LYS n 
1 238 GLY n 
1 239 GLU n 
1 240 ARG n 
1 241 LEU n 
1 242 PRO n 
1 243 GLN n 
1 244 PRO n 
1 245 PRO n 
1 246 ILE n 
1 247 CYS n 
1 248 THR n 
1 249 ILE n 
1 250 ASP n 
1 251 VAL n 
1 252 TYR n 
1 253 MET n 
1 254 ILE n 
1 255 MET n 
1 256 VAL n 
1 257 LYS n 
1 258 CYS n 
1 259 TRP n 
1 260 MET n 
1 261 ILE n 
1 262 ASP n 
1 263 ALA n 
1 264 ASP n 
1 265 SER n 
1 266 ARG n 
1 267 PRO n 
1 268 LYS n 
1 269 PHE n 
1 270 ARG n 
1 271 GLU n 
1 272 LEU n 
1 273 ILE n 
1 274 ILE n 
1 275 GLU n 
1 276 PHE n 
1 277 SER n 
1 278 LYS n 
1 279 MET n 
1 280 ALA n 
1 281 ARG n 
1 282 ASP n 
1 283 PRO n 
1 284 GLN n 
1 285 ARG n 
1 286 TYR n 
1 287 LEU n 
1 288 VAL n 
1 289 ILE n 
1 290 GLN n 
1 291 GLY n 
1 292 ASP n 
1 293 GLU n 
1 294 ARG n 
1 295 MET n 
1 296 HIS n 
1 297 LEU n 
1 298 PRO n 
1 299 SER n 
1 300 PRO n 
1 301 THR n 
1 302 ASP n 
1 303 SER n 
1 304 ASN n 
1 305 PHE n 
1 306 TYR n 
1 307 ARG n 
1 308 ALA n 
1 309 LEU n 
1 310 MET n 
1 311 ASP n 
1 312 GLU n 
1 313 GLU n 
1 314 ASP n 
1 315 MET n 
1 316 ASP n 
1 317 ASP n 
1 318 VAL n 
1 319 VAL n 
1 320 ASP n 
1 321 ALA n 
1 322 ASP n 
1 323 GLU n 
1 324 TYR n 
1 325 LEU n 
1 326 ILE n 
1 327 PRO n 
1 328 GLN n 
1 329 GLN n 
1 330 GLY n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   330 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'EGFR, ERBB, ERBB1, HER1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1A5V non-polymer         . 
'(4S)-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-methyl-1-(propan-2-yl)-1H-imidazo[1,2-b]pyrazol-6-amine' AUR-3418 
'C19 H27 N7 O'   369.464 
ALA   'L-peptide linking' y ALANINE ?        'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ?        'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ?        'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ?        'C4 H7 N O4'     133.103 
CL    non-polymer         . 'CHLORIDE ION' ?        'Cl -1'          35.453  
CYS   'L-peptide linking' y CYSTEINE ?        'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE ?        'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ?        'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ?        'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE ?        'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER ?        'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE ?        'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ?        'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ?        'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ?        'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ?        'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ?        'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ?        'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ?        'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ?        'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ?        'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE ?        'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   693  ?    ?   ?   A . n 
A 1 2   SER 2   694  694  SER SER A . n 
A 1 3   MET 3   695  695  MET MET A . n 
A 1 4   GLY 4   696  696  GLY GLY A . n 
A 1 5   GLU 5   697  697  GLU GLU A . n 
A 1 6   ALA 6   698  698  ALA ALA A . n 
A 1 7   PRO 7   699  699  PRO PRO A . n 
A 1 8   ASN 8   700  700  ASN ASN A . n 
A 1 9   GLN 9   701  701  GLN GLN A . n 
A 1 10  ALA 10  702  702  ALA ALA A . n 
A 1 11  LEU 11  703  703  LEU LEU A . n 
A 1 12  LEU 12  704  704  LEU LEU A . n 
A 1 13  ARG 13  705  705  ARG ARG A . n 
A 1 14  ILE 14  706  706  ILE ILE A . n 
A 1 15  LEU 15  707  707  LEU LEU A . n 
A 1 16  LYS 16  708  708  LYS LYS A . n 
A 1 17  GLU 17  709  709  GLU GLU A . n 
A 1 18  THR 18  710  710  THR THR A . n 
A 1 19  GLU 19  711  711  GLU GLU A . n 
A 1 20  PHE 20  712  712  PHE PHE A . n 
A 1 21  LYS 21  713  713  LYS LYS A . n 
A 1 22  LYS 22  714  714  LYS LYS A . n 
A 1 23  ILE 23  715  715  ILE ILE A . n 
A 1 24  LYS 24  716  716  LYS LYS A . n 
A 1 25  VAL 25  717  717  VAL VAL A . n 
A 1 26  LEU 26  718  718  LEU LEU A . n 
A 1 27  GLY 27  719  719  GLY GLY A . n 
A 1 28  SER 28  720  720  SER SER A . n 
A 1 29  GLY 29  721  721  GLY GLY A . n 
A 1 30  ALA 30  722  722  ALA ALA A . n 
A 1 31  PHE 31  723  723  PHE PHE A . n 
A 1 32  GLY 32  724  724  GLY GLY A . n 
A 1 33  THR 33  725  725  THR THR A . n 
A 1 34  VAL 34  726  726  VAL VAL A . n 
A 1 35  TYR 35  727  727  TYR TYR A . n 
A 1 36  LYS 36  728  728  LYS LYS A . n 
A 1 37  GLY 37  729  729  GLY GLY A . n 
A 1 38  LEU 38  730  730  LEU LEU A . n 
A 1 39  TRP 39  731  731  TRP TRP A . n 
A 1 40  ILE 40  732  732  ILE ILE A . n 
A 1 41  PRO 41  733  733  PRO PRO A . n 
A 1 42  GLU 42  734  734  GLU GLU A . n 
A 1 43  GLY 43  735  735  GLY GLY A . n 
A 1 44  GLU 44  736  736  GLU GLU A . n 
A 1 45  LYS 45  737  737  LYS LYS A . n 
A 1 46  VAL 46  738  738  VAL VAL A . n 
A 1 47  LYS 47  739  739  LYS LYS A . n 
A 1 48  ILE 48  740  740  ILE ILE A . n 
A 1 49  PRO 49  741  741  PRO PRO A . n 
A 1 50  VAL 50  742  742  VAL VAL A . n 
A 1 51  ALA 51  743  743  ALA ALA A . n 
A 1 52  ILE 52  744  744  ILE ILE A . n 
A 1 53  LYS 53  745  745  LYS LYS A . n 
A 1 54  GLU 54  746  746  GLU GLU A . n 
A 1 55  LEU 55  747  747  LEU LEU A . n 
A 1 56  ARG 56  748  748  ARG ARG A . n 
A 1 57  GLU 57  749  749  GLU GLU A . n 
A 1 58  ALA 58  750  750  ALA ALA A . n 
A 1 59  THR 59  751  751  THR THR A . n 
A 1 60  SER 60  752  752  SER SER A . n 
A 1 61  PRO 61  753  753  PRO PRO A . n 
A 1 62  LYS 62  754  754  LYS LYS A . n 
A 1 63  ALA 63  755  755  ALA ALA A . n 
A 1 64  ASN 64  756  756  ASN ASN A . n 
A 1 65  LYS 65  757  757  LYS LYS A . n 
A 1 66  GLU 66  758  758  GLU GLU A . n 
A 1 67  ILE 67  759  759  ILE ILE A . n 
A 1 68  LEU 68  760  760  LEU LEU A . n 
A 1 69  ASP 69  761  761  ASP ASP A . n 
A 1 70  GLU 70  762  762  GLU GLU A . n 
A 1 71  ALA 71  763  763  ALA ALA A . n 
A 1 72  TYR 72  764  764  TYR TYR A . n 
A 1 73  VAL 73  765  765  VAL VAL A . n 
A 1 74  MET 74  766  766  MET MET A . n 
A 1 75  ALA 75  767  767  ALA ALA A . n 
A 1 76  SER 76  768  768  SER SER A . n 
A 1 77  VAL 77  769  769  VAL VAL A . n 
A 1 78  ASP 78  770  770  ASP ASP A . n 
A 1 79  ASN 79  771  771  ASN ASN A . n 
A 1 80  PRO 80  772  772  PRO PRO A . n 
A 1 81  HIS 81  773  773  HIS HIS A . n 
A 1 82  VAL 82  774  774  VAL VAL A . n 
A 1 83  CYS 83  775  775  CYS CYS A . n 
A 1 84  ARG 84  776  776  ARG ARG A . n 
A 1 85  LEU 85  777  777  LEU LEU A . n 
A 1 86  LEU 86  778  778  LEU LEU A . n 
A 1 87  GLY 87  779  779  GLY GLY A . n 
A 1 88  ILE 88  780  780  ILE ILE A . n 
A 1 89  CYS 89  781  781  CYS CYS A . n 
A 1 90  LEU 90  782  782  LEU LEU A . n 
A 1 91  THR 91  783  783  THR THR A . n 
A 1 92  SER 92  784  784  SER SER A . n 
A 1 93  THR 93  785  785  THR THR A . n 
A 1 94  VAL 94  786  786  VAL VAL A . n 
A 1 95  GLN 95  787  787  GLN GLN A . n 
A 1 96  LEU 96  788  788  LEU LEU A . n 
A 1 97  ILE 97  789  789  ILE ILE A . n 
A 1 98  MET 98  790  790  MET MET A . n 
A 1 99  GLN 99  791  791  GLN GLN A . n 
A 1 100 LEU 100 792  792  LEU LEU A . n 
A 1 101 MET 101 793  793  MET MET A . n 
A 1 102 PRO 102 794  794  PRO PRO A . n 
A 1 103 PHE 103 795  795  PHE PHE A . n 
A 1 104 GLY 104 796  796  GLY GLY A . n 
A 1 105 SER 105 797  797  SER SER A . n 
A 1 106 LEU 106 798  798  LEU LEU A . n 
A 1 107 LEU 107 799  799  LEU LEU A . n 
A 1 108 ASP 108 800  800  ASP ASP A . n 
A 1 109 TYR 109 801  801  TYR TYR A . n 
A 1 110 VAL 110 802  802  VAL VAL A . n 
A 1 111 ARG 111 803  803  ARG ARG A . n 
A 1 112 GLU 112 804  804  GLU GLU A . n 
A 1 113 HIS 113 805  805  HIS HIS A . n 
A 1 114 LYS 114 806  806  LYS LYS A . n 
A 1 115 ASP 115 807  807  ASP ASP A . n 
A 1 116 ASN 116 808  808  ASN ASN A . n 
A 1 117 ILE 117 809  809  ILE ILE A . n 
A 1 118 GLY 118 810  810  GLY GLY A . n 
A 1 119 SER 119 811  811  SER SER A . n 
A 1 120 GLN 120 812  812  GLN GLN A . n 
A 1 121 TYR 121 813  813  TYR TYR A . n 
A 1 122 LEU 122 814  814  LEU LEU A . n 
A 1 123 LEU 123 815  815  LEU LEU A . n 
A 1 124 ASN 124 816  816  ASN ASN A . n 
A 1 125 TRP 125 817  817  TRP TRP A . n 
A 1 126 CYS 126 818  818  CYS CYS A . n 
A 1 127 VAL 127 819  819  VAL VAL A . n 
A 1 128 GLN 128 820  820  GLN GLN A . n 
A 1 129 ILE 129 821  821  ILE ILE A . n 
A 1 130 ALA 130 822  822  ALA ALA A . n 
A 1 131 LYS 131 823  823  LYS LYS A . n 
A 1 132 GLY 132 824  824  GLY GLY A . n 
A 1 133 MET 133 825  825  MET MET A . n 
A 1 134 ASN 134 826  826  ASN ASN A . n 
A 1 135 TYR 135 827  827  TYR TYR A . n 
A 1 136 LEU 136 828  828  LEU LEU A . n 
A 1 137 GLU 137 829  829  GLU GLU A . n 
A 1 138 ASP 138 830  830  ASP ASP A . n 
A 1 139 ARG 139 831  831  ARG ARG A . n 
A 1 140 ARG 140 832  832  ARG ARG A . n 
A 1 141 LEU 141 833  833  LEU LEU A . n 
A 1 142 VAL 142 834  834  VAL VAL A . n 
A 1 143 HIS 143 835  835  HIS HIS A . n 
A 1 144 ARG 144 836  836  ARG ARG A . n 
A 1 145 ASP 145 837  837  ASP ASP A . n 
A 1 146 LEU 146 838  838  LEU LEU A . n 
A 1 147 ALA 147 839  839  ALA ALA A . n 
A 1 148 ALA 148 840  840  ALA ALA A . n 
A 1 149 ARG 149 841  841  ARG ARG A . n 
A 1 150 ASN 150 842  842  ASN ASN A . n 
A 1 151 VAL 151 843  843  VAL VAL A . n 
A 1 152 LEU 152 844  844  LEU LEU A . n 
A 1 153 VAL 153 845  845  VAL VAL A . n 
A 1 154 LYS 154 846  846  LYS LYS A . n 
A 1 155 THR 155 847  847  THR THR A . n 
A 1 156 PRO 156 848  848  PRO PRO A . n 
A 1 157 GLN 157 849  849  GLN GLN A . n 
A 1 158 HIS 158 850  850  HIS HIS A . n 
A 1 159 VAL 159 851  851  VAL VAL A . n 
A 1 160 LYS 160 852  852  LYS LYS A . n 
A 1 161 ILE 161 853  853  ILE ILE A . n 
A 1 162 THR 162 854  854  THR THR A . n 
A 1 163 ASP 163 855  855  ASP ASP A . n 
A 1 164 PHE 164 856  856  PHE PHE A . n 
A 1 165 GLY 165 857  857  GLY GLY A . n 
A 1 166 ARG 166 858  858  ARG ARG A . n 
A 1 167 ALA 167 859  859  ALA ALA A . n 
A 1 168 LYS 168 860  860  LYS LYS A . n 
A 1 169 LEU 169 861  861  LEU LEU A . n 
A 1 170 LEU 170 862  862  LEU LEU A . n 
A 1 171 GLY 171 863  863  GLY GLY A . n 
A 1 172 ALA 172 864  864  ALA ALA A . n 
A 1 173 ALA 173 865  865  ALA ALA A . n 
A 1 174 ALA 174 866  866  ALA ALA A . n 
A 1 175 ALA 175 867  867  ALA ALA A . n 
A 1 176 GLU 176 868  868  GLU GLU A . n 
A 1 177 TYR 177 869  869  TYR TYR A . n 
A 1 178 HIS 178 870  870  HIS HIS A . n 
A 1 179 ALA 179 871  871  ALA ALA A . n 
A 1 180 GLU 180 872  872  GLU GLU A . n 
A 1 181 GLY 181 873  873  GLY GLY A . n 
A 1 182 GLY 182 874  874  GLY GLY A . n 
A 1 183 LYS 183 875  875  LYS LYS A . n 
A 1 184 VAL 184 876  876  VAL VAL A . n 
A 1 185 PRO 185 877  877  PRO PRO A . n 
A 1 186 ILE 186 878  878  ILE ILE A . n 
A 1 187 LYS 187 879  879  LYS LYS A . n 
A 1 188 TRP 188 880  880  TRP TRP A . n 
A 1 189 MET 189 881  881  MET MET A . n 
A 1 190 ALA 190 882  882  ALA ALA A . n 
A 1 191 LEU 191 883  883  LEU LEU A . n 
A 1 192 GLU 192 884  884  GLU GLU A . n 
A 1 193 SER 193 885  885  SER SER A . n 
A 1 194 ILE 194 886  886  ILE ILE A . n 
A 1 195 LEU 195 887  887  LEU LEU A . n 
A 1 196 HIS 196 888  888  HIS HIS A . n 
A 1 197 ARG 197 889  889  ARG ARG A . n 
A 1 198 ILE 198 890  890  ILE ILE A . n 
A 1 199 TYR 199 891  891  TYR TYR A . n 
A 1 200 THR 200 892  892  THR THR A . n 
A 1 201 HIS 201 893  893  HIS HIS A . n 
A 1 202 GLN 202 894  894  GLN GLN A . n 
A 1 203 SER 203 895  895  SER SER A . n 
A 1 204 ASP 204 896  896  ASP ASP A . n 
A 1 205 VAL 205 897  897  VAL VAL A . n 
A 1 206 TRP 206 898  898  TRP TRP A . n 
A 1 207 SER 207 899  899  SER SER A . n 
A 1 208 TYR 208 900  900  TYR TYR A . n 
A 1 209 GLY 209 901  901  GLY GLY A . n 
A 1 210 VAL 210 902  902  VAL VAL A . n 
A 1 211 THR 211 903  903  THR THR A . n 
A 1 212 VAL 212 904  904  VAL VAL A . n 
A 1 213 TRP 213 905  905  TRP TRP A . n 
A 1 214 GLU 214 906  906  GLU GLU A . n 
A 1 215 LEU 215 907  907  LEU LEU A . n 
A 1 216 MET 216 908  908  MET MET A . n 
A 1 217 THR 217 909  909  THR THR A . n 
A 1 218 PHE 218 910  910  PHE PHE A . n 
A 1 219 GLY 219 911  911  GLY GLY A . n 
A 1 220 SER 220 912  912  SER SER A . n 
A 1 221 LYS 221 913  913  LYS LYS A . n 
A 1 222 PRO 222 914  914  PRO PRO A . n 
A 1 223 TYR 223 915  915  TYR TYR A . n 
A 1 224 ASP 224 916  916  ASP ASP A . n 
A 1 225 GLY 225 917  917  GLY GLY A . n 
A 1 226 ILE 226 918  918  ILE ILE A . n 
A 1 227 PRO 227 919  919  PRO PRO A . n 
A 1 228 ALA 228 920  920  ALA ALA A . n 
A 1 229 SER 229 921  921  SER SER A . n 
A 1 230 GLU 230 922  922  GLU GLU A . n 
A 1 231 ILE 231 923  923  ILE ILE A . n 
A 1 232 SER 232 924  924  SER SER A . n 
A 1 233 SER 233 925  925  SER SER A . n 
A 1 234 ILE 234 926  926  ILE ILE A . n 
A 1 235 LEU 235 927  927  LEU LEU A . n 
A 1 236 GLU 236 928  928  GLU GLU A . n 
A 1 237 LYS 237 929  929  LYS LYS A . n 
A 1 238 GLY 238 930  930  GLY GLY A . n 
A 1 239 GLU 239 931  931  GLU GLU A . n 
A 1 240 ARG 240 932  932  ARG ARG A . n 
A 1 241 LEU 241 933  933  LEU LEU A . n 
A 1 242 PRO 242 934  934  PRO PRO A . n 
A 1 243 GLN 243 935  935  GLN GLN A . n 
A 1 244 PRO 244 936  936  PRO PRO A . n 
A 1 245 PRO 245 937  937  PRO PRO A . n 
A 1 246 ILE 246 938  938  ILE ILE A . n 
A 1 247 CYS 247 939  939  CYS CYS A . n 
A 1 248 THR 248 940  940  THR THR A . n 
A 1 249 ILE 249 941  941  ILE ILE A . n 
A 1 250 ASP 250 942  942  ASP ASP A . n 
A 1 251 VAL 251 943  943  VAL VAL A . n 
A 1 252 TYR 252 944  944  TYR TYR A . n 
A 1 253 MET 253 945  945  MET MET A . n 
A 1 254 ILE 254 946  946  ILE ILE A . n 
A 1 255 MET 255 947  947  MET MET A . n 
A 1 256 VAL 256 948  948  VAL VAL A . n 
A 1 257 LYS 257 949  949  LYS LYS A . n 
A 1 258 CYS 258 950  950  CYS CYS A . n 
A 1 259 TRP 259 951  951  TRP TRP A . n 
A 1 260 MET 260 952  952  MET MET A . n 
A 1 261 ILE 261 953  953  ILE ILE A . n 
A 1 262 ASP 262 954  954  ASP ASP A . n 
A 1 263 ALA 263 955  955  ALA ALA A . n 
A 1 264 ASP 264 956  956  ASP ASP A . n 
A 1 265 SER 265 957  957  SER SER A . n 
A 1 266 ARG 266 958  958  ARG ARG A . n 
A 1 267 PRO 267 959  959  PRO PRO A . n 
A 1 268 LYS 268 960  960  LYS LYS A . n 
A 1 269 PHE 269 961  961  PHE PHE A . n 
A 1 270 ARG 270 962  962  ARG ARG A . n 
A 1 271 GLU 271 963  963  GLU GLU A . n 
A 1 272 LEU 272 964  964  LEU LEU A . n 
A 1 273 ILE 273 965  965  ILE ILE A . n 
A 1 274 ILE 274 966  966  ILE ILE A . n 
A 1 275 GLU 275 967  967  GLU GLU A . n 
A 1 276 PHE 276 968  968  PHE PHE A . n 
A 1 277 SER 277 969  969  SER SER A . n 
A 1 278 LYS 278 970  970  LYS LYS A . n 
A 1 279 MET 279 971  971  MET MET A . n 
A 1 280 ALA 280 972  972  ALA ALA A . n 
A 1 281 ARG 281 973  973  ARG ARG A . n 
A 1 282 ASP 282 974  974  ASP ASP A . n 
A 1 283 PRO 283 975  975  PRO PRO A . n 
A 1 284 GLN 284 976  976  GLN GLN A . n 
A 1 285 ARG 285 977  977  ARG ARG A . n 
A 1 286 TYR 286 978  978  TYR TYR A . n 
A 1 287 LEU 287 979  979  LEU LEU A . n 
A 1 288 VAL 288 980  980  VAL VAL A . n 
A 1 289 ILE 289 981  981  ILE ILE A . n 
A 1 290 GLN 290 982  982  GLN GLN A . n 
A 1 291 GLY 291 983  983  GLY GLY A . n 
A 1 292 ASP 292 984  984  ASP ASP A . n 
A 1 293 GLU 293 985  985  GLU GLU A . n 
A 1 294 ARG 294 986  986  ARG ARG A . n 
A 1 295 MET 295 987  987  MET MET A . n 
A 1 296 HIS 296 988  988  HIS HIS A . n 
A 1 297 LEU 297 989  989  LEU LEU A . n 
A 1 298 PRO 298 990  990  PRO PRO A . n 
A 1 299 SER 299 991  991  SER SER A . n 
A 1 300 PRO 300 992  992  PRO PRO A . n 
A 1 301 THR 301 993  993  THR THR A . n 
A 1 302 ASP 302 994  994  ASP ASP A . n 
A 1 303 SER 303 995  995  SER SER A . n 
A 1 304 ASN 304 996  ?    ?   ?   A . n 
A 1 305 PHE 305 997  ?    ?   ?   A . n 
A 1 306 TYR 306 998  ?    ?   ?   A . n 
A 1 307 ARG 307 999  ?    ?   ?   A . n 
A 1 308 ALA 308 1000 ?    ?   ?   A . n 
A 1 309 LEU 309 1001 ?    ?   ?   A . n 
A 1 310 MET 310 1002 ?    ?   ?   A . n 
A 1 311 ASP 311 1003 ?    ?   ?   A . n 
A 1 312 GLU 312 1004 ?    ?   ?   A . n 
A 1 313 GLU 313 1005 1005 GLU GLU A . n 
A 1 314 ASP 314 1006 1006 ASP ASP A . n 
A 1 315 MET 315 1007 1007 MET MET A . n 
A 1 316 ASP 316 1008 1008 ASP ASP A . n 
A 1 317 ASP 317 1009 1009 ASP ASP A . n 
A 1 318 VAL 318 1010 1010 VAL VAL A . n 
A 1 319 VAL 319 1011 1011 VAL VAL A . n 
A 1 320 ASP 320 1012 1012 ASP ASP A . n 
A 1 321 ALA 321 1013 1013 ALA ALA A . n 
A 1 322 ASP 322 1014 1014 ASP ASP A . n 
A 1 323 GLU 323 1015 1015 GLU GLU A . n 
A 1 324 TYR 324 1016 1016 TYR TYR A . n 
A 1 325 LEU 325 1017 1017 LEU LEU A . n 
A 1 326 ILE 326 1018 1018 ILE ILE A . n 
A 1 327 PRO 327 1019 1019 PRO PRO A . n 
A 1 328 GLN 328 1020 ?    ?   ?   A . n 
A 1 329 GLN 329 1021 ?    ?   ?   A . n 
A 1 330 GLY 330 1022 ?    ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1A5V 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1A5V 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1A5V 1  1101 1  A1A5V INX A . 
C 3 CL    1  1102 1  CL    CL  A . 
D 3 CL    1  1103 2  CL    CL  A . 
E 3 CL    1  1104 3  CL    CL  A . 
F 3 CL    1  1105 4  CL    CL  A . 
G 4 HOH   1  1201 27 HOH   HOH A . 
G 4 HOH   2  1202 20 HOH   HOH A . 
G 4 HOH   3  1203 38 HOH   HOH A . 
G 4 HOH   4  1204 4  HOH   HOH A . 
G 4 HOH   5  1205 22 HOH   HOH A . 
G 4 HOH   6  1206 1  HOH   HOH A . 
G 4 HOH   7  1207 54 HOH   HOH A . 
G 4 HOH   8  1208 3  HOH   HOH A . 
G 4 HOH   9  1209 51 HOH   HOH A . 
G 4 HOH   10 1210 21 HOH   HOH A . 
G 4 HOH   11 1211 29 HOH   HOH A . 
G 4 HOH   12 1212 58 HOH   HOH A . 
G 4 HOH   13 1213 36 HOH   HOH A . 
G 4 HOH   14 1214 11 HOH   HOH A . 
G 4 HOH   15 1215 30 HOH   HOH A . 
G 4 HOH   16 1216 26 HOH   HOH A . 
G 4 HOH   17 1217 39 HOH   HOH A . 
G 4 HOH   18 1218 17 HOH   HOH A . 
G 4 HOH   19 1219 52 HOH   HOH A . 
G 4 HOH   20 1220 1  HOH   HOH A . 
G 4 HOH   21 1221 53 HOH   HOH A . 
G 4 HOH   22 1222 40 HOH   HOH A . 
G 4 HOH   23 1223 55 HOH   HOH A . 
G 4 HOH   24 1224 23 HOH   HOH A . 
G 4 HOH   25 1225 3  HOH   HOH A . 
G 4 HOH   26 1226 12 HOH   HOH A . 
G 4 HOH   27 1227 14 HOH   HOH A . 
G 4 HOH   28 1228 18 HOH   HOH A . 
G 4 HOH   29 1229 5  HOH   HOH A . 
G 4 HOH   30 1230 42 HOH   HOH A . 
G 4 HOH   31 1231 15 HOH   HOH A . 
G 4 HOH   32 1232 56 HOH   HOH A . 
G 4 HOH   33 1233 61 HOH   HOH A . 
G 4 HOH   34 1234 4  HOH   HOH A . 
G 4 HOH   35 1235 2  HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A GLU 1005 ? CG  ? A GLU 313 CG  
2 1 Y 1 A GLU 1005 ? CD  ? A GLU 313 CD  
3 1 Y 1 A GLU 1005 ? OE1 ? A GLU 313 OE1 
4 1 Y 1 A GLU 1005 ? OE2 ? A GLU 313 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PRIME-X ? ? ? . 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? . 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? . 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? . 4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9D3V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     145.736 
_cell.length_a_esd                 ? 
_cell.length_b                     145.736 
_cell.length_b_esd                 ? 
_cell.length_c                     145.736 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9D3V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                197 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'I 2 3' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9D3V 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.44 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          64.27 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.96 M SUCCINIC ACID, 1.0 %(W/V) POLYETHYLENE GLYCOL MONOMETHYL ETHER 2000, 0.1 M HEPES' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            294 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 S 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-05-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.00000 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SLS BEAMLINE X10SA' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.00000 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   X10SA 
_diffrn_source.pdbx_synchrotron_site       SLS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9D3V 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.32 
_reflns.d_resolution_low                               103.05 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     22479 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                25.46 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          26.49 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.080 
_reflns.pdbx_Rpim_I_all                                0.016 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.9998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.079 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.32 
_reflns_shell.d_res_low                                     2.36 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.258 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1117 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               3.056 
_reflns_shell.pdbx_Rpim_I_all                               0.596 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.5730 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100. 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  2.997 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               58.39 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9D3V 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.32 
_refine.ls_d_res_low                             72.87 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     22478 
_refine.ls_number_reflns_R_free                  1253 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.0 
_refine.ls_percent_reflns_R_free                 5.6 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.329 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.299 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 96.12 
_refine.solvent_model_param_ksol                 0.311 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            random 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.32 
_refine_hist.d_res_low                        72.87 
_refine_hist.number_atoms_solvent             36 
_refine_hist.number_atoms_total               2582 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2515 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         31 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
_refine_ls_restr.pdbx_refine_id            'X-RAY DIFFRACTION' 
_refine_ls_restr.criterion                 ? 
_refine_ls_restr.dev_ideal                 ? 
_refine_ls_restr.dev_ideal_target          ? 
_refine_ls_restr.number                    ? 
_refine_ls_restr.rejects                   ? 
_refine_ls_restr.type                      'OPLS 2005X' 
_refine_ls_restr.weight                    ? 
_refine_ls_restr.pdbx_restraint_function   ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.32 
_refine_ls_shell.d_res_low                        2.40 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             135 
_refine_ls_shell.number_reflns_R_work             2247 
_refine_ls_shell.percent_reflns_obs               100.0 
_refine_ls_shell.percent_reflns_R_free            6.0 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.990 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   ? 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.992 
# 
_struct.entry_id                     9D3V 
_struct.title                        'CRYSTAL STRUCTURE OF EGFR(L858R/T790M/C797S) IN COMPLEX WITH AUR-3418' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9D3V 
_struct_keywords.text            'protein kinase, inhibitor, kinase domain, TRANSFERASE, TRANSFERASE-INHIBITOR complex' 
_struct_keywords.pdbx_keywords   TRANSFERASE/INHIBITOR 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    EGFR_HUMAN 
_struct_ref.pdbx_db_accession          P00533 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVC
RLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITD
FGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQ
PPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADE
YLIPQQG
;
_struct_ref.pdbx_align_begin           696 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9D3V 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 4 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 330 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P00533 
_struct_ref_seq.db_align_beg                  696 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1022 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       696 
_struct_ref_seq.pdbx_auth_seq_align_end       1022 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9D3V GLY A 1   ? UNP P00533 ?   ?   'expression tag'      693 1 
1 9D3V SER A 2   ? UNP P00533 ?   ?   'expression tag'      694 2 
1 9D3V MET A 3   ? UNP P00533 ?   ?   'expression tag'      695 3 
1 9D3V MET A 98  ? UNP P00533 THR 790 variant               790 4 
1 9D3V SER A 105 ? UNP P00533 CYS 797 'engineered mutation' 797 5 
1 9D3V ARG A 166 ? UNP P00533 LEU 858 variant               858 6 
1 9D3V ALA A 173 ? UNP P00533 GLU 865 'engineered mutation' 865 7 
1 9D3V ALA A 174 ? UNP P00533 GLU 866 'engineered mutation' 866 8 
1 9D3V ALA A 175 ? UNP P00533 LYS 867 'engineered mutation' 867 9 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 16  ? THR A 18  ? LYS A 708  THR A 710  5 ? 3  
HELX_P HELX_P2  AA2 SER A 60  ? VAL A 77  ? SER A 752  VAL A 769  1 ? 18 
HELX_P HELX_P3  AA3 SER A 105 ? LYS A 114 ? SER A 797  LYS A 806  1 ? 10 
HELX_P HELX_P4  AA4 ASP A 115 ? ILE A 117 ? ASP A 807  ILE A 809  5 ? 3  
HELX_P HELX_P5  AA5 GLY A 118 ? ARG A 139 ? GLY A 810  ARG A 831  1 ? 22 
HELX_P HELX_P6  AA6 ALA A 147 ? ARG A 149 ? ALA A 839  ARG A 841  5 ? 3  
HELX_P HELX_P7  AA7 PRO A 185 ? MET A 189 ? PRO A 877  MET A 881  5 ? 5  
HELX_P HELX_P8  AA8 ALA A 190 ? ARG A 197 ? ALA A 882  ARG A 889  1 ? 8  
HELX_P HELX_P9  AA9 THR A 200 ? THR A 217 ? THR A 892  THR A 909  1 ? 18 
HELX_P HELX_P10 AB1 PRO A 227 ? LYS A 237 ? PRO A 919  LYS A 929  1 ? 11 
HELX_P HELX_P11 AB2 THR A 248 ? TRP A 259 ? THR A 940  TRP A 951  1 ? 12 
HELX_P HELX_P12 AB3 ASP A 262 ? ARG A 266 ? ASP A 954  ARG A 958  5 ? 5  
HELX_P HELX_P13 AB4 LYS A 268 ? ARG A 281 ? LYS A 960  ARG A 973  1 ? 14 
HELX_P HELX_P14 AB5 ASP A 282 ? TYR A 286 ? ASP A 974  TYR A 978  5 ? 5  
HELX_P HELX_P15 AB6 GLY A 291 ? MET A 295 ? GLY A 983  MET A 987  5 ? 5  
HELX_P HELX_P16 AB7 ASP A 320 ? TYR A 324 ? ASP A 1012 TYR A 1016 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 20  ? GLY A 29  ? PHE A 712 GLY A 721 
AA1 2 GLY A 32  ? TRP A 39  ? GLY A 724 TRP A 731 
AA1 3 ILE A 48  ? GLU A 54  ? ILE A 740 GLU A 746 
AA1 4 GLN A 95  ? GLN A 99  ? GLN A 787 GLN A 791 
AA1 5 LEU A 85  ? CYS A 89  ? LEU A 777 CYS A 781 
AA2 1 LEU A 141 ? VAL A 142 ? LEU A 833 VAL A 834 
AA2 2 LYS A 168 ? LEU A 169 ? LYS A 860 LEU A 861 
AA3 1 VAL A 151 ? THR A 155 ? VAL A 843 THR A 847 
AA3 2 HIS A 158 ? ILE A 161 ? HIS A 850 ILE A 853 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 23  ? N ILE A 715 O LYS A 36  ? O LYS A 728 
AA1 2 3 N TRP A 39  ? N TRP A 731 O ILE A 48  ? O ILE A 740 
AA1 3 4 N ALA A 51  ? N ALA A 743 O MET A 98  ? O MET A 790 
AA1 4 5 O ILE A 97  ? O ILE A 789 N GLY A 87  ? N GLY A 779 
AA2 1 2 N VAL A 142 ? N VAL A 834 O LYS A 168 ? O LYS A 860 
AA3 1 2 N LEU A 152 ? N LEU A 844 O LYS A 160 ? O LYS A 852 
# 
_pdbx_entry_details.entry_id                   9D3V 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 748 ? ? 82.46   29.71   
2  1 GLU A 749 ? ? 80.11   17.97   
3  1 THR A 751 ? ? -71.99  34.21   
4  1 ARG A 836 ? ? 80.85   -3.01   
5  1 ASP A 837 ? ? -148.87 36.46   
6  1 ASP A 855 ? ? 71.87   82.32   
7  1 ALA A 864 ? ? -142.76 58.03   
8  1 ALA A 865 ? ? 86.25   18.00   
9  1 ALA A 866 ? ? 76.00   -8.36   
10 1 ALA A 867 ? ? -83.49  48.07   
11 1 GLU A 868 ? ? -97.65  51.48   
12 1 TYR A 869 ? ? -147.39 31.67   
13 1 LYS A 875 ? ? -143.14 48.28   
14 1 SER A 991 ? ? -137.25 -42.86  
15 1 ASP A 994 ? ? -76.81  -106.28 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 693  ? A GLY 1   
2  1 Y 1 A ASN 996  ? A ASN 304 
3  1 Y 1 A PHE 997  ? A PHE 305 
4  1 Y 1 A TYR 998  ? A TYR 306 
5  1 Y 1 A ARG 999  ? A ARG 307 
6  1 Y 1 A ALA 1000 ? A ALA 308 
7  1 Y 1 A LEU 1001 ? A LEU 309 
8  1 Y 1 A MET 1002 ? A MET 310 
9  1 Y 1 A ASP 1003 ? A ASP 311 
10 1 Y 1 A GLU 1004 ? A GLU 312 
11 1 Y 1 A GLN 1020 ? A GLN 328 
12 1 Y 1 A GLN 1021 ? A GLN 329 
13 1 Y 1 A GLY 1022 ? A GLY 330 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1A5V C1   C  N N 1   
A1A5V C3   C  N N 2   
A1A5V C4   C  N N 3   
A1A5V C5   C  N N 4   
A1A5V C7   C  N N 5   
A1A5V C8   C  N N 6   
A1A5V N10  N  Y N 7   
A1A5V C11  C  Y N 8   
A1A5V C12  C  Y N 9   
A1A5V C15  C  Y N 10  
A1A5V C18  C  Y N 11  
A1A5V C19  C  Y N 12  
A1A5V C23  C  N N 13  
A1A5V C24  C  N N 14  
A1A5V O2   O  N N 15  
A1A5V N6   N  N N 16  
A1A5V C9   C  Y N 17  
A1A5V C13  C  Y N 18  
A1A5V N14  N  N N 19  
A1A5V N16  N  Y N 20  
A1A5V N17  N  Y N 21  
A1A5V C20  C  N N 22  
A1A5V N21  N  Y N 23  
A1A5V C22  C  N N 24  
A1A5V C25  C  Y N 25  
A1A5V C26  C  Y N 26  
A1A5V N27  N  Y N 27  
A1A5V H1_1 H  N N 28  
A1A5V H1_3 H  N N 29  
A1A5V H1_2 H  N N 30  
A1A5V HC3  H  N N 31  
A1A5V H4_2 H  N N 32  
A1A5V H4_1 H  N N 33  
A1A5V H5_1 H  N N 34  
A1A5V H5_2 H  N N 35  
A1A5V H7_1 H  N N 36  
A1A5V H7_2 H  N N 37  
A1A5V H8_1 H  N N 38  
A1A5V H8_2 H  N N 39  
A1A5V HC11 H  N N 40  
A1A5V HC12 H  N N 41  
A1A5V HC18 H  N N 42  
A1A5V H232 H  N N 43  
A1A5V H231 H  N N 44  
A1A5V H233 H  N N 45  
A1A5V H243 H  N N 46  
A1A5V H242 H  N N 47  
A1A5V H241 H  N N 48  
A1A5V HN14 H  N N 49  
A1A5V H203 H  N N 50  
A1A5V H202 H  N N 51  
A1A5V H201 H  N N 52  
A1A5V HC22 H  N N 53  
A1A5V HC26 H  N N 54  
ALA   N    N  N N 55  
ALA   CA   C  N S 56  
ALA   C    C  N N 57  
ALA   O    O  N N 58  
ALA   CB   C  N N 59  
ALA   OXT  O  N N 60  
ALA   H    H  N N 61  
ALA   H2   H  N N 62  
ALA   HA   H  N N 63  
ALA   HB1  H  N N 64  
ALA   HB2  H  N N 65  
ALA   HB3  H  N N 66  
ALA   HXT  H  N N 67  
ARG   N    N  N N 68  
ARG   CA   C  N S 69  
ARG   C    C  N N 70  
ARG   O    O  N N 71  
ARG   CB   C  N N 72  
ARG   CG   C  N N 73  
ARG   CD   C  N N 74  
ARG   NE   N  N N 75  
ARG   CZ   C  N N 76  
ARG   NH1  N  N N 77  
ARG   NH2  N  N N 78  
ARG   OXT  O  N N 79  
ARG   H    H  N N 80  
ARG   H2   H  N N 81  
ARG   HA   H  N N 82  
ARG   HB2  H  N N 83  
ARG   HB3  H  N N 84  
ARG   HG2  H  N N 85  
ARG   HG3  H  N N 86  
ARG   HD2  H  N N 87  
ARG   HD3  H  N N 88  
ARG   HE   H  N N 89  
ARG   HH11 H  N N 90  
ARG   HH12 H  N N 91  
ARG   HH21 H  N N 92  
ARG   HH22 H  N N 93  
ARG   HXT  H  N N 94  
ASN   N    N  N N 95  
ASN   CA   C  N S 96  
ASN   C    C  N N 97  
ASN   O    O  N N 98  
ASN   CB   C  N N 99  
ASN   CG   C  N N 100 
ASN   OD1  O  N N 101 
ASN   ND2  N  N N 102 
ASN   OXT  O  N N 103 
ASN   H    H  N N 104 
ASN   H2   H  N N 105 
ASN   HA   H  N N 106 
ASN   HB2  H  N N 107 
ASN   HB3  H  N N 108 
ASN   HD21 H  N N 109 
ASN   HD22 H  N N 110 
ASN   HXT  H  N N 111 
ASP   N    N  N N 112 
ASP   CA   C  N S 113 
ASP   C    C  N N 114 
ASP   O    O  N N 115 
ASP   CB   C  N N 116 
ASP   CG   C  N N 117 
ASP   OD1  O  N N 118 
ASP   OD2  O  N N 119 
ASP   OXT  O  N N 120 
ASP   H    H  N N 121 
ASP   H2   H  N N 122 
ASP   HA   H  N N 123 
ASP   HB2  H  N N 124 
ASP   HB3  H  N N 125 
ASP   HD2  H  N N 126 
ASP   HXT  H  N N 127 
CL    CL   CL N N 128 
CYS   N    N  N N 129 
CYS   CA   C  N R 130 
CYS   C    C  N N 131 
CYS   O    O  N N 132 
CYS   CB   C  N N 133 
CYS   SG   S  N N 134 
CYS   OXT  O  N N 135 
CYS   H    H  N N 136 
CYS   H2   H  N N 137 
CYS   HA   H  N N 138 
CYS   HB2  H  N N 139 
CYS   HB3  H  N N 140 
CYS   HG   H  N N 141 
CYS   HXT  H  N N 142 
GLN   N    N  N N 143 
GLN   CA   C  N S 144 
GLN   C    C  N N 145 
GLN   O    O  N N 146 
GLN   CB   C  N N 147 
GLN   CG   C  N N 148 
GLN   CD   C  N N 149 
GLN   OE1  O  N N 150 
GLN   NE2  N  N N 151 
GLN   OXT  O  N N 152 
GLN   H    H  N N 153 
GLN   H2   H  N N 154 
GLN   HA   H  N N 155 
GLN   HB2  H  N N 156 
GLN   HB3  H  N N 157 
GLN   HG2  H  N N 158 
GLN   HG3  H  N N 159 
GLN   HE21 H  N N 160 
GLN   HE22 H  N N 161 
GLN   HXT  H  N N 162 
GLU   N    N  N N 163 
GLU   CA   C  N S 164 
GLU   C    C  N N 165 
GLU   O    O  N N 166 
GLU   CB   C  N N 167 
GLU   CG   C  N N 168 
GLU   CD   C  N N 169 
GLU   OE1  O  N N 170 
GLU   OE2  O  N N 171 
GLU   OXT  O  N N 172 
GLU   H    H  N N 173 
GLU   H2   H  N N 174 
GLU   HA   H  N N 175 
GLU   HB2  H  N N 176 
GLU   HB3  H  N N 177 
GLU   HG2  H  N N 178 
GLU   HG3  H  N N 179 
GLU   HE2  H  N N 180 
GLU   HXT  H  N N 181 
GLY   N    N  N N 182 
GLY   CA   C  N N 183 
GLY   C    C  N N 184 
GLY   O    O  N N 185 
GLY   OXT  O  N N 186 
GLY   H    H  N N 187 
GLY   H2   H  N N 188 
GLY   HA2  H  N N 189 
GLY   HA3  H  N N 190 
GLY   HXT  H  N N 191 
HIS   N    N  N N 192 
HIS   CA   C  N S 193 
HIS   C    C  N N 194 
HIS   O    O  N N 195 
HIS   CB   C  N N 196 
HIS   CG   C  Y N 197 
HIS   ND1  N  Y N 198 
HIS   CD2  C  Y N 199 
HIS   CE1  C  Y N 200 
HIS   NE2  N  Y N 201 
HIS   OXT  O  N N 202 
HIS   H    H  N N 203 
HIS   H2   H  N N 204 
HIS   HA   H  N N 205 
HIS   HB2  H  N N 206 
HIS   HB3  H  N N 207 
HIS   HD1  H  N N 208 
HIS   HD2  H  N N 209 
HIS   HE1  H  N N 210 
HIS   HE2  H  N N 211 
HIS   HXT  H  N N 212 
HOH   O    O  N N 213 
HOH   H1   H  N N 214 
HOH   H2   H  N N 215 
ILE   N    N  N N 216 
ILE   CA   C  N S 217 
ILE   C    C  N N 218 
ILE   O    O  N N 219 
ILE   CB   C  N S 220 
ILE   CG1  C  N N 221 
ILE   CG2  C  N N 222 
ILE   CD1  C  N N 223 
ILE   OXT  O  N N 224 
ILE   H    H  N N 225 
ILE   H2   H  N N 226 
ILE   HA   H  N N 227 
ILE   HB   H  N N 228 
ILE   HG12 H  N N 229 
ILE   HG13 H  N N 230 
ILE   HG21 H  N N 231 
ILE   HG22 H  N N 232 
ILE   HG23 H  N N 233 
ILE   HD11 H  N N 234 
ILE   HD12 H  N N 235 
ILE   HD13 H  N N 236 
ILE   HXT  H  N N 237 
LEU   N    N  N N 238 
LEU   CA   C  N S 239 
LEU   C    C  N N 240 
LEU   O    O  N N 241 
LEU   CB   C  N N 242 
LEU   CG   C  N N 243 
LEU   CD1  C  N N 244 
LEU   CD2  C  N N 245 
LEU   OXT  O  N N 246 
LEU   H    H  N N 247 
LEU   H2   H  N N 248 
LEU   HA   H  N N 249 
LEU   HB2  H  N N 250 
LEU   HB3  H  N N 251 
LEU   HG   H  N N 252 
LEU   HD11 H  N N 253 
LEU   HD12 H  N N 254 
LEU   HD13 H  N N 255 
LEU   HD21 H  N N 256 
LEU   HD22 H  N N 257 
LEU   HD23 H  N N 258 
LEU   HXT  H  N N 259 
LYS   N    N  N N 260 
LYS   CA   C  N S 261 
LYS   C    C  N N 262 
LYS   O    O  N N 263 
LYS   CB   C  N N 264 
LYS   CG   C  N N 265 
LYS   CD   C  N N 266 
LYS   CE   C  N N 267 
LYS   NZ   N  N N 268 
LYS   OXT  O  N N 269 
LYS   H    H  N N 270 
LYS   H2   H  N N 271 
LYS   HA   H  N N 272 
LYS   HB2  H  N N 273 
LYS   HB3  H  N N 274 
LYS   HG2  H  N N 275 
LYS   HG3  H  N N 276 
LYS   HD2  H  N N 277 
LYS   HD3  H  N N 278 
LYS   HE2  H  N N 279 
LYS   HE3  H  N N 280 
LYS   HZ1  H  N N 281 
LYS   HZ2  H  N N 282 
LYS   HZ3  H  N N 283 
LYS   HXT  H  N N 284 
MET   N    N  N N 285 
MET   CA   C  N S 286 
MET   C    C  N N 287 
MET   O    O  N N 288 
MET   CB   C  N N 289 
MET   CG   C  N N 290 
MET   SD   S  N N 291 
MET   CE   C  N N 292 
MET   OXT  O  N N 293 
MET   H    H  N N 294 
MET   H2   H  N N 295 
MET   HA   H  N N 296 
MET   HB2  H  N N 297 
MET   HB3  H  N N 298 
MET   HG2  H  N N 299 
MET   HG3  H  N N 300 
MET   HE1  H  N N 301 
MET   HE2  H  N N 302 
MET   HE3  H  N N 303 
MET   HXT  H  N N 304 
PHE   N    N  N N 305 
PHE   CA   C  N S 306 
PHE   C    C  N N 307 
PHE   O    O  N N 308 
PHE   CB   C  N N 309 
PHE   CG   C  Y N 310 
PHE   CD1  C  Y N 311 
PHE   CD2  C  Y N 312 
PHE   CE1  C  Y N 313 
PHE   CE2  C  Y N 314 
PHE   CZ   C  Y N 315 
PHE   OXT  O  N N 316 
PHE   H    H  N N 317 
PHE   H2   H  N N 318 
PHE   HA   H  N N 319 
PHE   HB2  H  N N 320 
PHE   HB3  H  N N 321 
PHE   HD1  H  N N 322 
PHE   HD2  H  N N 323 
PHE   HE1  H  N N 324 
PHE   HE2  H  N N 325 
PHE   HZ   H  N N 326 
PHE   HXT  H  N N 327 
PRO   N    N  N N 328 
PRO   CA   C  N S 329 
PRO   C    C  N N 330 
PRO   O    O  N N 331 
PRO   CB   C  N N 332 
PRO   CG   C  N N 333 
PRO   CD   C  N N 334 
PRO   OXT  O  N N 335 
PRO   H    H  N N 336 
PRO   HA   H  N N 337 
PRO   HB2  H  N N 338 
PRO   HB3  H  N N 339 
PRO   HG2  H  N N 340 
PRO   HG3  H  N N 341 
PRO   HD2  H  N N 342 
PRO   HD3  H  N N 343 
PRO   HXT  H  N N 344 
SER   N    N  N N 345 
SER   CA   C  N S 346 
SER   C    C  N N 347 
SER   O    O  N N 348 
SER   CB   C  N N 349 
SER   OG   O  N N 350 
SER   OXT  O  N N 351 
SER   H    H  N N 352 
SER   H2   H  N N 353 
SER   HA   H  N N 354 
SER   HB2  H  N N 355 
SER   HB3  H  N N 356 
SER   HG   H  N N 357 
SER   HXT  H  N N 358 
THR   N    N  N N 359 
THR   CA   C  N S 360 
THR   C    C  N N 361 
THR   O    O  N N 362 
THR   CB   C  N R 363 
THR   OG1  O  N N 364 
THR   CG2  C  N N 365 
THR   OXT  O  N N 366 
THR   H    H  N N 367 
THR   H2   H  N N 368 
THR   HA   H  N N 369 
THR   HB   H  N N 370 
THR   HG1  H  N N 371 
THR   HG21 H  N N 372 
THR   HG22 H  N N 373 
THR   HG23 H  N N 374 
THR   HXT  H  N N 375 
TRP   N    N  N N 376 
TRP   CA   C  N S 377 
TRP   C    C  N N 378 
TRP   O    O  N N 379 
TRP   CB   C  N N 380 
TRP   CG   C  Y N 381 
TRP   CD1  C  Y N 382 
TRP   CD2  C  Y N 383 
TRP   NE1  N  Y N 384 
TRP   CE2  C  Y N 385 
TRP   CE3  C  Y N 386 
TRP   CZ2  C  Y N 387 
TRP   CZ3  C  Y N 388 
TRP   CH2  C  Y N 389 
TRP   OXT  O  N N 390 
TRP   H    H  N N 391 
TRP   H2   H  N N 392 
TRP   HA   H  N N 393 
TRP   HB2  H  N N 394 
TRP   HB3  H  N N 395 
TRP   HD1  H  N N 396 
TRP   HE1  H  N N 397 
TRP   HE3  H  N N 398 
TRP   HZ2  H  N N 399 
TRP   HZ3  H  N N 400 
TRP   HH2  H  N N 401 
TRP   HXT  H  N N 402 
TYR   N    N  N N 403 
TYR   CA   C  N S 404 
TYR   C    C  N N 405 
TYR   O    O  N N 406 
TYR   CB   C  N N 407 
TYR   CG   C  Y N 408 
TYR   CD1  C  Y N 409 
TYR   CD2  C  Y N 410 
TYR   CE1  C  Y N 411 
TYR   CE2  C  Y N 412 
TYR   CZ   C  Y N 413 
TYR   OH   O  N N 414 
TYR   OXT  O  N N 415 
TYR   H    H  N N 416 
TYR   H2   H  N N 417 
TYR   HA   H  N N 418 
TYR   HB2  H  N N 419 
TYR   HB3  H  N N 420 
TYR   HD1  H  N N 421 
TYR   HD2  H  N N 422 
TYR   HE1  H  N N 423 
TYR   HE2  H  N N 424 
TYR   HH   H  N N 425 
TYR   HXT  H  N N 426 
VAL   N    N  N N 427 
VAL   CA   C  N S 428 
VAL   C    C  N N 429 
VAL   O    O  N N 430 
VAL   CB   C  N N 431 
VAL   CG1  C  N N 432 
VAL   CG2  C  N N 433 
VAL   OXT  O  N N 434 
VAL   H    H  N N 435 
VAL   H2   H  N N 436 
VAL   HA   H  N N 437 
VAL   HB   H  N N 438 
VAL   HG11 H  N N 439 
VAL   HG12 H  N N 440 
VAL   HG13 H  N N 441 
VAL   HG21 H  N N 442 
VAL   HG22 H  N N 443 
VAL   HG23 H  N N 444 
VAL   HXT  H  N N 445 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1A5V C20 C19  sing N N 1   
A1A5V C19 C18  doub Y N 2   
A1A5V C19 N21  sing Y N 3   
A1A5V C18 N17  sing Y N 4   
A1A5V N21 C22  sing N N 5   
A1A5V N21 C25  sing Y N 6   
A1A5V N17 C25  sing Y N 7   
A1A5V N17 N16  sing Y N 8   
A1A5V C22 C23  sing N N 9   
A1A5V C22 C24  sing N N 10  
A1A5V C25 C26  doub Y N 11  
A1A5V N16 C15  doub Y N 12  
A1A5V C26 C15  sing Y N 13  
A1A5V C15 N14  sing N N 14  
A1A5V N14 C13  sing N N 15  
A1A5V C13 N27  doub Y N 16  
A1A5V C13 C12  sing Y N 17  
A1A5V N27 C9   sing Y N 18  
A1A5V C5  C4   sing N N 19  
A1A5V C5  N6   sing N N 20  
A1A5V C12 C11  doub Y N 21  
A1A5V C4  C3   sing N N 22  
A1A5V C9  N6   sing N N 23  
A1A5V C9  N10  doub Y N 24  
A1A5V N6  C7   sing N N 25  
A1A5V C11 N10  sing Y N 26  
A1A5V C3  O2   sing N N 27  
A1A5V C3  C8   sing N N 28  
A1A5V C1  O2   sing N N 29  
A1A5V C7  C8   sing N N 30  
A1A5V C1  H1_1 sing N N 31  
A1A5V C1  H1_3 sing N N 32  
A1A5V C1  H1_2 sing N N 33  
A1A5V C3  HC3  sing N N 34  
A1A5V C4  H4_2 sing N N 35  
A1A5V C4  H4_1 sing N N 36  
A1A5V C5  H5_1 sing N N 37  
A1A5V C5  H5_2 sing N N 38  
A1A5V C7  H7_1 sing N N 39  
A1A5V C7  H7_2 sing N N 40  
A1A5V C8  H8_1 sing N N 41  
A1A5V C8  H8_2 sing N N 42  
A1A5V C11 HC11 sing N N 43  
A1A5V C12 HC12 sing N N 44  
A1A5V C18 HC18 sing N N 45  
A1A5V C23 H232 sing N N 46  
A1A5V C23 H231 sing N N 47  
A1A5V C23 H233 sing N N 48  
A1A5V C24 H243 sing N N 49  
A1A5V C24 H242 sing N N 50  
A1A5V C24 H241 sing N N 51  
A1A5V N14 HN14 sing N N 52  
A1A5V C20 H203 sing N N 53  
A1A5V C20 H202 sing N N 54  
A1A5V C20 H201 sing N N 55  
A1A5V C22 HC22 sing N N 56  
A1A5V C26 HC26 sing N N 57  
ALA   N   CA   sing N N 58  
ALA   N   H    sing N N 59  
ALA   N   H2   sing N N 60  
ALA   CA  C    sing N N 61  
ALA   CA  CB   sing N N 62  
ALA   CA  HA   sing N N 63  
ALA   C   O    doub N N 64  
ALA   C   OXT  sing N N 65  
ALA   CB  HB1  sing N N 66  
ALA   CB  HB2  sing N N 67  
ALA   CB  HB3  sing N N 68  
ALA   OXT HXT  sing N N 69  
ARG   N   CA   sing N N 70  
ARG   N   H    sing N N 71  
ARG   N   H2   sing N N 72  
ARG   CA  C    sing N N 73  
ARG   CA  CB   sing N N 74  
ARG   CA  HA   sing N N 75  
ARG   C   O    doub N N 76  
ARG   C   OXT  sing N N 77  
ARG   CB  CG   sing N N 78  
ARG   CB  HB2  sing N N 79  
ARG   CB  HB3  sing N N 80  
ARG   CG  CD   sing N N 81  
ARG   CG  HG2  sing N N 82  
ARG   CG  HG3  sing N N 83  
ARG   CD  NE   sing N N 84  
ARG   CD  HD2  sing N N 85  
ARG   CD  HD3  sing N N 86  
ARG   NE  CZ   sing N N 87  
ARG   NE  HE   sing N N 88  
ARG   CZ  NH1  sing N N 89  
ARG   CZ  NH2  doub N N 90  
ARG   NH1 HH11 sing N N 91  
ARG   NH1 HH12 sing N N 92  
ARG   NH2 HH21 sing N N 93  
ARG   NH2 HH22 sing N N 94  
ARG   OXT HXT  sing N N 95  
ASN   N   CA   sing N N 96  
ASN   N   H    sing N N 97  
ASN   N   H2   sing N N 98  
ASN   CA  C    sing N N 99  
ASN   CA  CB   sing N N 100 
ASN   CA  HA   sing N N 101 
ASN   C   O    doub N N 102 
ASN   C   OXT  sing N N 103 
ASN   CB  CG   sing N N 104 
ASN   CB  HB2  sing N N 105 
ASN   CB  HB3  sing N N 106 
ASN   CG  OD1  doub N N 107 
ASN   CG  ND2  sing N N 108 
ASN   ND2 HD21 sing N N 109 
ASN   ND2 HD22 sing N N 110 
ASN   OXT HXT  sing N N 111 
ASP   N   CA   sing N N 112 
ASP   N   H    sing N N 113 
ASP   N   H2   sing N N 114 
ASP   CA  C    sing N N 115 
ASP   CA  CB   sing N N 116 
ASP   CA  HA   sing N N 117 
ASP   C   O    doub N N 118 
ASP   C   OXT  sing N N 119 
ASP   CB  CG   sing N N 120 
ASP   CB  HB2  sing N N 121 
ASP   CB  HB3  sing N N 122 
ASP   CG  OD1  doub N N 123 
ASP   CG  OD2  sing N N 124 
ASP   OD2 HD2  sing N N 125 
ASP   OXT HXT  sing N N 126 
CYS   N   CA   sing N N 127 
CYS   N   H    sing N N 128 
CYS   N   H2   sing N N 129 
CYS   CA  C    sing N N 130 
CYS   CA  CB   sing N N 131 
CYS   CA  HA   sing N N 132 
CYS   C   O    doub N N 133 
CYS   C   OXT  sing N N 134 
CYS   CB  SG   sing N N 135 
CYS   CB  HB2  sing N N 136 
CYS   CB  HB3  sing N N 137 
CYS   SG  HG   sing N N 138 
CYS   OXT HXT  sing N N 139 
GLN   N   CA   sing N N 140 
GLN   N   H    sing N N 141 
GLN   N   H2   sing N N 142 
GLN   CA  C    sing N N 143 
GLN   CA  CB   sing N N 144 
GLN   CA  HA   sing N N 145 
GLN   C   O    doub N N 146 
GLN   C   OXT  sing N N 147 
GLN   CB  CG   sing N N 148 
GLN   CB  HB2  sing N N 149 
GLN   CB  HB3  sing N N 150 
GLN   CG  CD   sing N N 151 
GLN   CG  HG2  sing N N 152 
GLN   CG  HG3  sing N N 153 
GLN   CD  OE1  doub N N 154 
GLN   CD  NE2  sing N N 155 
GLN   NE2 HE21 sing N N 156 
GLN   NE2 HE22 sing N N 157 
GLN   OXT HXT  sing N N 158 
GLU   N   CA   sing N N 159 
GLU   N   H    sing N N 160 
GLU   N   H2   sing N N 161 
GLU   CA  C    sing N N 162 
GLU   CA  CB   sing N N 163 
GLU   CA  HA   sing N N 164 
GLU   C   O    doub N N 165 
GLU   C   OXT  sing N N 166 
GLU   CB  CG   sing N N 167 
GLU   CB  HB2  sing N N 168 
GLU   CB  HB3  sing N N 169 
GLU   CG  CD   sing N N 170 
GLU   CG  HG2  sing N N 171 
GLU   CG  HG3  sing N N 172 
GLU   CD  OE1  doub N N 173 
GLU   CD  OE2  sing N N 174 
GLU   OE2 HE2  sing N N 175 
GLU   OXT HXT  sing N N 176 
GLY   N   CA   sing N N 177 
GLY   N   H    sing N N 178 
GLY   N   H2   sing N N 179 
GLY   CA  C    sing N N 180 
GLY   CA  HA2  sing N N 181 
GLY   CA  HA3  sing N N 182 
GLY   C   O    doub N N 183 
GLY   C   OXT  sing N N 184 
GLY   OXT HXT  sing N N 185 
HIS   N   CA   sing N N 186 
HIS   N   H    sing N N 187 
HIS   N   H2   sing N N 188 
HIS   CA  C    sing N N 189 
HIS   CA  CB   sing N N 190 
HIS   CA  HA   sing N N 191 
HIS   C   O    doub N N 192 
HIS   C   OXT  sing N N 193 
HIS   CB  CG   sing N N 194 
HIS   CB  HB2  sing N N 195 
HIS   CB  HB3  sing N N 196 
HIS   CG  ND1  sing Y N 197 
HIS   CG  CD2  doub Y N 198 
HIS   ND1 CE1  doub Y N 199 
HIS   ND1 HD1  sing N N 200 
HIS   CD2 NE2  sing Y N 201 
HIS   CD2 HD2  sing N N 202 
HIS   CE1 NE2  sing Y N 203 
HIS   CE1 HE1  sing N N 204 
HIS   NE2 HE2  sing N N 205 
HIS   OXT HXT  sing N N 206 
HOH   O   H1   sing N N 207 
HOH   O   H2   sing N N 208 
ILE   N   CA   sing N N 209 
ILE   N   H    sing N N 210 
ILE   N   H2   sing N N 211 
ILE   CA  C    sing N N 212 
ILE   CA  CB   sing N N 213 
ILE   CA  HA   sing N N 214 
ILE   C   O    doub N N 215 
ILE   C   OXT  sing N N 216 
ILE   CB  CG1  sing N N 217 
ILE   CB  CG2  sing N N 218 
ILE   CB  HB   sing N N 219 
ILE   CG1 CD1  sing N N 220 
ILE   CG1 HG12 sing N N 221 
ILE   CG1 HG13 sing N N 222 
ILE   CG2 HG21 sing N N 223 
ILE   CG2 HG22 sing N N 224 
ILE   CG2 HG23 sing N N 225 
ILE   CD1 HD11 sing N N 226 
ILE   CD1 HD12 sing N N 227 
ILE   CD1 HD13 sing N N 228 
ILE   OXT HXT  sing N N 229 
LEU   N   CA   sing N N 230 
LEU   N   H    sing N N 231 
LEU   N   H2   sing N N 232 
LEU   CA  C    sing N N 233 
LEU   CA  CB   sing N N 234 
LEU   CA  HA   sing N N 235 
LEU   C   O    doub N N 236 
LEU   C   OXT  sing N N 237 
LEU   CB  CG   sing N N 238 
LEU   CB  HB2  sing N N 239 
LEU   CB  HB3  sing N N 240 
LEU   CG  CD1  sing N N 241 
LEU   CG  CD2  sing N N 242 
LEU   CG  HG   sing N N 243 
LEU   CD1 HD11 sing N N 244 
LEU   CD1 HD12 sing N N 245 
LEU   CD1 HD13 sing N N 246 
LEU   CD2 HD21 sing N N 247 
LEU   CD2 HD22 sing N N 248 
LEU   CD2 HD23 sing N N 249 
LEU   OXT HXT  sing N N 250 
LYS   N   CA   sing N N 251 
LYS   N   H    sing N N 252 
LYS   N   H2   sing N N 253 
LYS   CA  C    sing N N 254 
LYS   CA  CB   sing N N 255 
LYS   CA  HA   sing N N 256 
LYS   C   O    doub N N 257 
LYS   C   OXT  sing N N 258 
LYS   CB  CG   sing N N 259 
LYS   CB  HB2  sing N N 260 
LYS   CB  HB3  sing N N 261 
LYS   CG  CD   sing N N 262 
LYS   CG  HG2  sing N N 263 
LYS   CG  HG3  sing N N 264 
LYS   CD  CE   sing N N 265 
LYS   CD  HD2  sing N N 266 
LYS   CD  HD3  sing N N 267 
LYS   CE  NZ   sing N N 268 
LYS   CE  HE2  sing N N 269 
LYS   CE  HE3  sing N N 270 
LYS   NZ  HZ1  sing N N 271 
LYS   NZ  HZ2  sing N N 272 
LYS   NZ  HZ3  sing N N 273 
LYS   OXT HXT  sing N N 274 
MET   N   CA   sing N N 275 
MET   N   H    sing N N 276 
MET   N   H2   sing N N 277 
MET   CA  C    sing N N 278 
MET   CA  CB   sing N N 279 
MET   CA  HA   sing N N 280 
MET   C   O    doub N N 281 
MET   C   OXT  sing N N 282 
MET   CB  CG   sing N N 283 
MET   CB  HB2  sing N N 284 
MET   CB  HB3  sing N N 285 
MET   CG  SD   sing N N 286 
MET   CG  HG2  sing N N 287 
MET   CG  HG3  sing N N 288 
MET   SD  CE   sing N N 289 
MET   CE  HE1  sing N N 290 
MET   CE  HE2  sing N N 291 
MET   CE  HE3  sing N N 292 
MET   OXT HXT  sing N N 293 
PHE   N   CA   sing N N 294 
PHE   N   H    sing N N 295 
PHE   N   H2   sing N N 296 
PHE   CA  C    sing N N 297 
PHE   CA  CB   sing N N 298 
PHE   CA  HA   sing N N 299 
PHE   C   O    doub N N 300 
PHE   C   OXT  sing N N 301 
PHE   CB  CG   sing N N 302 
PHE   CB  HB2  sing N N 303 
PHE   CB  HB3  sing N N 304 
PHE   CG  CD1  doub Y N 305 
PHE   CG  CD2  sing Y N 306 
PHE   CD1 CE1  sing Y N 307 
PHE   CD1 HD1  sing N N 308 
PHE   CD2 CE2  doub Y N 309 
PHE   CD2 HD2  sing N N 310 
PHE   CE1 CZ   doub Y N 311 
PHE   CE1 HE1  sing N N 312 
PHE   CE2 CZ   sing Y N 313 
PHE   CE2 HE2  sing N N 314 
PHE   CZ  HZ   sing N N 315 
PHE   OXT HXT  sing N N 316 
PRO   N   CA   sing N N 317 
PRO   N   CD   sing N N 318 
PRO   N   H    sing N N 319 
PRO   CA  C    sing N N 320 
PRO   CA  CB   sing N N 321 
PRO   CA  HA   sing N N 322 
PRO   C   O    doub N N 323 
PRO   C   OXT  sing N N 324 
PRO   CB  CG   sing N N 325 
PRO   CB  HB2  sing N N 326 
PRO   CB  HB3  sing N N 327 
PRO   CG  CD   sing N N 328 
PRO   CG  HG2  sing N N 329 
PRO   CG  HG3  sing N N 330 
PRO   CD  HD2  sing N N 331 
PRO   CD  HD3  sing N N 332 
PRO   OXT HXT  sing N N 333 
SER   N   CA   sing N N 334 
SER   N   H    sing N N 335 
SER   N   H2   sing N N 336 
SER   CA  C    sing N N 337 
SER   CA  CB   sing N N 338 
SER   CA  HA   sing N N 339 
SER   C   O    doub N N 340 
SER   C   OXT  sing N N 341 
SER   CB  OG   sing N N 342 
SER   CB  HB2  sing N N 343 
SER   CB  HB3  sing N N 344 
SER   OG  HG   sing N N 345 
SER   OXT HXT  sing N N 346 
THR   N   CA   sing N N 347 
THR   N   H    sing N N 348 
THR   N   H2   sing N N 349 
THR   CA  C    sing N N 350 
THR   CA  CB   sing N N 351 
THR   CA  HA   sing N N 352 
THR   C   O    doub N N 353 
THR   C   OXT  sing N N 354 
THR   CB  OG1  sing N N 355 
THR   CB  CG2  sing N N 356 
THR   CB  HB   sing N N 357 
THR   OG1 HG1  sing N N 358 
THR   CG2 HG21 sing N N 359 
THR   CG2 HG22 sing N N 360 
THR   CG2 HG23 sing N N 361 
THR   OXT HXT  sing N N 362 
TRP   N   CA   sing N N 363 
TRP   N   H    sing N N 364 
TRP   N   H2   sing N N 365 
TRP   CA  C    sing N N 366 
TRP   CA  CB   sing N N 367 
TRP   CA  HA   sing N N 368 
TRP   C   O    doub N N 369 
TRP   C   OXT  sing N N 370 
TRP   CB  CG   sing N N 371 
TRP   CB  HB2  sing N N 372 
TRP   CB  HB3  sing N N 373 
TRP   CG  CD1  doub Y N 374 
TRP   CG  CD2  sing Y N 375 
TRP   CD1 NE1  sing Y N 376 
TRP   CD1 HD1  sing N N 377 
TRP   CD2 CE2  doub Y N 378 
TRP   CD2 CE3  sing Y N 379 
TRP   NE1 CE2  sing Y N 380 
TRP   NE1 HE1  sing N N 381 
TRP   CE2 CZ2  sing Y N 382 
TRP   CE3 CZ3  doub Y N 383 
TRP   CE3 HE3  sing N N 384 
TRP   CZ2 CH2  doub Y N 385 
TRP   CZ2 HZ2  sing N N 386 
TRP   CZ3 CH2  sing Y N 387 
TRP   CZ3 HZ3  sing N N 388 
TRP   CH2 HH2  sing N N 389 
TRP   OXT HXT  sing N N 390 
TYR   N   CA   sing N N 391 
TYR   N   H    sing N N 392 
TYR   N   H2   sing N N 393 
TYR   CA  C    sing N N 394 
TYR   CA  CB   sing N N 395 
TYR   CA  HA   sing N N 396 
TYR   C   O    doub N N 397 
TYR   C   OXT  sing N N 398 
TYR   CB  CG   sing N N 399 
TYR   CB  HB2  sing N N 400 
TYR   CB  HB3  sing N N 401 
TYR   CG  CD1  doub Y N 402 
TYR   CG  CD2  sing Y N 403 
TYR   CD1 CE1  sing Y N 404 
TYR   CD1 HD1  sing N N 405 
TYR   CD2 CE2  doub Y N 406 
TYR   CD2 HD2  sing N N 407 
TYR   CE1 CZ   doub Y N 408 
TYR   CE1 HE1  sing N N 409 
TYR   CE2 CZ   sing Y N 410 
TYR   CE2 HE2  sing N N 411 
TYR   CZ  OH   sing N N 412 
TYR   OH  HH   sing N N 413 
TYR   OXT HXT  sing N N 414 
VAL   N   CA   sing N N 415 
VAL   N   H    sing N N 416 
VAL   N   H2   sing N N 417 
VAL   CA  C    sing N N 418 
VAL   CA  CB   sing N N 419 
VAL   CA  HA   sing N N 420 
VAL   C   O    doub N N 421 
VAL   C   OXT  sing N N 422 
VAL   CB  CG1  sing N N 423 
VAL   CB  CG2  sing N N 424 
VAL   CB  HB   sing N N 425 
VAL   CG1 HG11 sing N N 426 
VAL   CG1 HG12 sing N N 427 
VAL   CG1 HG13 sing N N 428 
VAL   CG2 HG21 sing N N 429 
VAL   CG2 HG22 sing N N 430 
VAL   CG2 HG23 sing N N 431 
VAL   OXT HXT  sing N N 432 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6LUD 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9D3V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006862 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006862 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006862 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
F  
H  
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . SER   A 1 2   ? 67.887 -5.842  59.898 1.00 110.86 1  694  SER   A N    1 
ATOM   2    C  CA   . SER   A 1 2   ? 67.213 -6.491  58.759 1.00 108.03 ?  694  SER   A CA   1 
ATOM   3    C  C    . SER   A 1 2   ? 67.833 -6.005  57.462 1.00 110.78 ?  694  SER   A C    1 
ATOM   4    O  O    . SER   A 1 2   ? 68.026 -4.801  57.287 1.00 115.00 ?  694  SER   A O    1 
ATOM   5    C  CB   . SER   A 1 2   ? 65.718 -6.172  58.769 1.00 108.48 ?  694  SER   A CB   1 
ATOM   6    O  OG   . SER   A 1 2   ? 64.995 -6.863  59.781 1.00 104.44 ?  694  SER   A OG   1 
ATOM   7    H  H    . SER   A 1 2   ? 67.370 -6.019  60.745 1.00 112.86 ?  694  SER   A H    1 
ATOM   8    H  HA   . SER   A 1 2   ? 67.357 -7.569  58.847 1.00 110.03 ?  694  SER   A HA   1 
ATOM   9    H  HB2  . SER   A 1 2   ? 65.560 -5.098  58.876 1.00 110.48 ?  694  SER   A HB2  1 
ATOM   10   H  HB3  . SER   A 1 2   ? 65.271 -6.453  57.813 1.00 110.48 ?  694  SER   A HB3  1 
ATOM   11   H  HG   . SER   A 1 2   ? 64.089 -6.558  59.726 1.00 106.44 ?  694  SER   A HG   1 
ATOM   12   N  N    . MET   A 1 3   ? 68.117 -6.920  56.536 1.00 108.31 ?  695  MET   A N    1 
ATOM   13   C  CA   . MET   A 1 3   ? 68.312 -6.525  55.146 1.00 105.27 ?  695  MET   A CA   1 
ATOM   14   C  C    . MET   A 1 3   ? 68.086 -7.745  54.286 1.00 102.66 ?  695  MET   A C    1 
ATOM   15   O  O    . MET   A 1 3   ? 68.771 -8.753  54.466 1.00 102.34 ?  695  MET   A O    1 
ATOM   16   C  CB   . MET   A 1 3   ? 69.658 -5.843  54.856 1.00 103.46 ?  695  MET   A CB   1 
ATOM   17   C  CG   . MET   A 1 3   ? 69.645 -4.975  53.603 1.00 99.19  ?  695  MET   A CG   1 
ATOM   18   S  SD   . MET   A 1 3   ? 68.483 -3.600  53.755 1.00 103.10 ?  695  MET   A SD   1 
ATOM   19   C  CE   . MET   A 1 3   ? 68.861 -2.692  52.272 1.00 93.81  ?  695  MET   A CE   1 
ATOM   20   H  H    . MET   A 1 3   ? 67.986 -7.908  56.701 1.00 110.31 ?  695  MET   A H    1 
ATOM   21   H  HA   . MET   A 1 3   ? 67.507 -5.825  54.921 1.00 107.27 ?  695  MET   A HA   1 
ATOM   22   H  HB2  . MET   A 1 3   ? 69.963 -5.215  55.692 1.00 105.46 ?  695  MET   A HB2  1 
ATOM   23   H  HB3  . MET   A 1 3   ? 70.440 -6.596  54.762 1.00 105.46 ?  695  MET   A HB3  1 
ATOM   24   H  HG2  . MET   A 1 3   ? 70.643 -4.565  53.441 1.00 101.19 ?  695  MET   A HG2  1 
ATOM   25   H  HG3  . MET   A 1 3   ? 69.399 -5.562  52.717 1.00 101.19 ?  695  MET   A HG3  1 
ATOM   26   H  HE1  . MET   A 1 3   ? 68.776 -3.330  51.396 1.00 95.81  ?  695  MET   A HE1  1 
ATOM   27   H  HE2  . MET   A 1 3   ? 68.166 -1.859  52.175 1.00 95.81  ?  695  MET   A HE2  1 
ATOM   28   H  HE3  . MET   A 1 3   ? 69.874 -2.292  52.315 1.00 95.81  ?  695  MET   A HE3  1 
ATOM   29   N  N    . GLY   A 1 4   ? 67.129 -7.653  53.374 1.00 97.44  ?  696  GLY   A N    1 
ATOM   30   C  CA   . GLY   A 1 4   ? 66.823 -8.786  52.507 1.00 90.42  ?  696  GLY   A CA   1 
ATOM   31   C  C    . GLY   A 1 4   ? 66.955 -8.496  51.028 1.00 85.25  ?  696  GLY   A C    1 
ATOM   32   O  O    . GLY   A 1 4   ? 67.300 -9.378  50.240 1.00 94.05  ?  696  GLY   A O    1 
ATOM   33   H  H    . GLY   A 1 4   ? 66.551 -6.822  53.341 1.00 99.44  ?  696  GLY   A H    1 
ATOM   34   H  HA2  . GLY   A 1 4   ? 67.406 -9.683  52.728 1.00 92.42  ?  696  GLY   A HA2  1 
ATOM   35   H  HA3  . GLY   A 1 4   ? 65.786 -9.067  52.690 1.00 92.42  ?  696  GLY   A HA3  1 
ATOM   36   N  N    . GLU   A 1 5   ? 66.685 -7.254  50.656 1.00 68.82  ?  697  GLU   A N    1 
ATOM   37   C  CA   . GLU   A 1 5   ? 66.648 -6.834  49.267 1.00 56.27  ?  697  GLU   A CA   1 
ATOM   38   C  C    . GLU   A 1 5   ? 67.093 -5.382  49.235 1.00 50.06  ?  697  GLU   A C    1 
ATOM   39   O  O    . GLU   A 1 5   ? 66.935 -4.659  50.224 1.00 52.90  ?  697  GLU   A O    1 
ATOM   40   C  CB   . GLU   A 1 5   ? 65.290 -7.173  48.635 1.00 63.93  ?  697  GLU   A CB   1 
ATOM   41   C  CG   . GLU   A 1 5   ? 64.991 -6.687  47.216 1.00 79.76  ?  697  GLU   A CG   1 
ATOM   42   C  CD   . GLU   A 1 5   ? 65.845 -7.442  46.226 1.00 100.43 ?  697  GLU   A CD   1 
ATOM   43   O  OE1  . GLU   A 1 5   ? 65.417 -8.518  45.755 1.00 96.89  ?  697  GLU   A OE1  1 
ATOM   44   O  OE2  . GLU   A 1 5   ? 66.961 -6.975  45.914 1.00 105.17 -1 697  GLU   A OE2  1 
ATOM   45   H  H    . GLU   A 1 5   ? 66.522 -6.527  51.337 1.00 70.82  ?  697  GLU   A H    1 
ATOM   46   H  HA   . GLU   A 1 5   ? 67.415 -7.386  48.719 1.00 58.27  ?  697  GLU   A HA   1 
ATOM   47   H  HB2  . GLU   A 1 5   ? 65.141 -8.254  48.670 1.00 65.93  ?  697  GLU   A HB2  1 
ATOM   48   H  HB3  . GLU   A 1 5   ? 64.512 -6.772  49.279 1.00 65.93  ?  697  GLU   A HB3  1 
ATOM   49   H  HG2  . GLU   A 1 5   ? 63.941 -6.856  46.975 1.00 81.76  ?  697  GLU   A HG2  1 
ATOM   50   H  HG3  . GLU   A 1 5   ? 65.168 -5.616  47.121 1.00 81.76  ?  697  GLU   A HG3  1 
ATOM   51   N  N    . ALA   A 1 6   ? 67.692 -4.959  48.131 1.00 39.76  ?  698  ALA   A N    1 
ATOM   52   C  CA   . ALA   A 1 6   ? 68.200 -3.588  48.049 1.00 43.70  ?  698  ALA   A CA   1 
ATOM   53   C  C    . ALA   A 1 6   ? 67.069 -2.585  47.813 1.00 41.43  ?  698  ALA   A C    1 
ATOM   54   O  O    . ALA   A 1 6   ? 66.073 -2.943  47.171 1.00 36.54  ?  698  ALA   A O    1 
ATOM   55   C  CB   . ALA   A 1 6   ? 69.161 -3.474  46.879 1.00 37.87  ?  698  ALA   A CB   1 
ATOM   56   H  H    . ALA   A 1 6   ? 67.672 -5.543  47.303 1.00 41.76  ?  698  ALA   A H    1 
ATOM   57   H  HA   . ALA   A 1 6   ? 68.743 -3.365  48.968 1.00 45.70  ?  698  ALA   A HA   1 
ATOM   58   H  HB1  . ALA   A 1 6   ? 69.581 -2.472  46.786 1.00 39.87  ?  698  ALA   A HB1  1 
ATOM   59   H  HB2  . ALA   A 1 6   ? 69.998 -4.163  46.996 1.00 39.87  ?  698  ALA   A HB2  1 
ATOM   60   H  HB3  . ALA   A 1 6   ? 68.671 -3.710  45.932 1.00 39.87  ?  698  ALA   A HB3  1 
ATOM   61   N  N    . PRO   A 1 7   ? 67.195 -1.336  48.289 1.00 39.32  ?  699  PRO   A N    1 
ATOM   62   C  CA   . PRO   A 1 7   ? 66.164 -0.323  48.097 1.00 32.41  ?  699  PRO   A CA   1 
ATOM   63   C  C    . PRO   A 1 7   ? 65.984 0.071   46.645 1.00 36.03  ?  699  PRO   A C    1 
ATOM   64   O  O    . PRO   A 1 7   ? 66.952 0.268   45.905 1.00 37.20  ?  699  PRO   A O    1 
ATOM   65   C  CB   . PRO   A 1 7   ? 66.589 0.859   48.955 1.00 28.49  ?  699  PRO   A CB   1 
ATOM   66   C  CG   . PRO   A 1 7   ? 68.081 0.674   49.200 1.00 22.31  ?  699  PRO   A CG   1 
ATOM   67   C  CD   . PRO   A 1 7   ? 68.348 -0.827  49.031 1.00 33.30  ?  699  PRO   A CD   1 
ATOM   68   H  HA   . PRO   A 1 7   ? 65.224 -0.723  48.479 1.00 34.41  ?  699  PRO   A HA   1 
ATOM   69   H  HB2  . PRO   A 1 7   ? 66.368 1.829   48.508 1.00 30.49  ?  699  PRO   A HB2  1 
ATOM   70   H  HB3  . PRO   A 1 7   ? 66.070 0.831   49.912 1.00 30.49  ?  699  PRO   A HB3  1 
ATOM   71   H  HG2  . PRO   A 1 7   ? 68.637 1.228   48.440 1.00 24.31  ?  699  PRO   A HG2  1 
ATOM   72   H  HG3  . PRO   A 1 7   ? 68.397 1.049   50.175 1.00 24.31  ?  699  PRO   A HG3  1 
ATOM   73   H  HD2  . PRO   A 1 7   ? 69.296 -0.998  48.521 1.00 35.30  ?  699  PRO   A HD2  1 
ATOM   74   H  HD3  . PRO   A 1 7   ? 68.385 -1.306  50.005 1.00 35.30  ?  699  PRO   A HD3  1 
ATOM   75   N  N    . ASN   A 1 8   ? 64.725 0.188   46.250 1.00 27.08  ?  700  ASN   A N    1 
ATOM   76   C  CA   . ASN   A 1 8   ? 64.411 0.598   44.892 1.00 36.82  ?  700  ASN   A CA   1 
ATOM   77   C  C    . ASN   A 1 8   ? 64.357 2.122   44.862 1.00 35.14  ?  700  ASN   A C    1 
ATOM   78   O  O    . ASN   A 1 8   ? 63.356 2.766   45.197 1.00 40.05  ?  700  ASN   A O    1 
ATOM   79   C  CB   . ASN   A 1 8   ? 63.061 0.005   44.486 1.00 32.33  ?  700  ASN   A CB   1 
ATOM   80   C  CG   . ASN   A 1 8   ? 62.725 0.235   43.035 1.00 34.70  ?  700  ASN   A CG   1 
ATOM   81   O  OD1  . ASN   A 1 8   ? 63.372 1.018   42.338 1.00 30.10  ?  700  ASN   A OD1  1 
ATOM   82   N  ND2  . ASN   A 1 8   ? 61.703 -0.441  42.560 1.00 27.24  ?  700  ASN   A ND2  1 
ATOM   83   H  H    . ASN   A 1 8   ? 63.955 0.019   46.901 1.00 29.08  ?  700  ASN   A H    1 
ATOM   84   H  HA   . ASN   A 1 8   ? 65.163 0.228   44.189 1.00 38.82  ?  700  ASN   A HA   1 
ATOM   85   H  HB2  . ASN   A 1 8   ? 63.074 -1.071  44.664 1.00 34.33  ?  700  ASN   A HB2  1 
ATOM   86   H  HB3  . ASN   A 1 8   ? 62.254 0.407   45.100 1.00 34.33  ?  700  ASN   A HB3  1 
ATOM   87   H  HD21 . ASN   A 1 8   ? 61.174 -1.065  43.163 1.00 29.24  ?  700  ASN   A HD21 1 
ATOM   88   H  HD22 . ASN   A 1 8   ? 61.420 -0.313  41.581 1.00 29.24  ?  700  ASN   A HD22 1 
ATOM   89   N  N    . GLN   A 1 9   ? 65.463 2.695   44.432 1.00 35.86  ?  701  GLN   A N    1 
ATOM   90   C  CA   . GLN   A 1 9   ? 65.574 4.150   44.365 1.00 39.04  ?  701  GLN   A CA   1 
ATOM   91   C  C    . GLN   A 1 9   ? 65.151 4.732   43.013 1.00 32.22  ?  701  GLN   A C    1 
ATOM   92   O  O    . GLN   A 1 9   ? 65.549 5.840   42.646 1.00 40.93  ?  701  GLN   A O    1 
ATOM   93   C  CB   . GLN   A 1 9   ? 67.014 4.538   44.666 1.00 36.78  ?  701  GLN   A CB   1 
ATOM   94   C  CG   . GLN   A 1 9   ? 67.479 4.113   46.062 1.00 42.90  ?  701  GLN   A CG   1 
ATOM   95   C  CD   . GLN   A 1 9   ? 68.792 4.754   46.443 1.00 51.39  ?  701  GLN   A CD   1 
ATOM   96   O  OE1  . GLN   A 1 9   ? 69.772 4.080   46.743 1.00 52.00  ?  701  GLN   A OE1  1 
ATOM   97   N  NE2  . GLN   A 1 9   ? 68.830 6.067   46.433 1.00 49.22  ?  701  GLN   A NE2  1 
ATOM   98   H  H    . GLN   A 1 9   ? 66.262 2.119   44.210 1.00 37.86  ?  701  GLN   A H    1 
ATOM   99   H  HA   . GLN   A 1 9   ? 64.945 4.632   45.116 1.00 41.04  ?  701  GLN   A HA   1 
ATOM   100  H  HB2  . GLN   A 1 9   ? 67.680 4.104   43.919 1.00 38.78  ?  701  GLN   A HB2  1 
ATOM   101  H  HB3  . GLN   A 1 9   ? 67.123 5.617   44.553 1.00 38.78  ?  701  GLN   A HB3  1 
ATOM   102  H  HG2  . GLN   A 1 9   ? 66.735 4.393   46.809 1.00 44.90  ?  701  GLN   A HG2  1 
ATOM   103  H  HG3  . GLN   A 1 9   ? 67.583 3.028   46.122 1.00 44.90  ?  701  GLN   A HG3  1 
ATOM   104  H  HE21 . GLN   A 1 9   ? 68.003 6.596   46.183 1.00 51.22  ?  701  GLN   A HE21 1 
ATOM   105  H  HE22 . GLN   A 1 9   ? 69.682 6.547   46.677 1.00 51.22  ?  701  GLN   A HE22 1 
ATOM   106  N  N    . ALA   A 1 10  ? 64.347 3.999   42.247 1.00 29.14  ?  702  ALA   A N    1 
ATOM   107  C  CA   . ALA   A 1 10  ? 63.742 4.589   41.056 1.00 31.04  ?  702  ALA   A CA   1 
ATOM   108  C  C    . ALA   A 1 10  ? 62.890 5.830   41.347 1.00 42.30  ?  702  ALA   A C    1 
ATOM   109  O  O    . ALA   A 1 10  ? 62.259 5.937   42.407 1.00 33.84  ?  702  ALA   A O    1 
ATOM   110  C  CB   . ALA   A 1 10  ? 62.897 3.557   40.353 1.00 18.70  ?  702  ALA   A CB   1 
ATOM   111  H  H    . ALA   A 1 10  ? 64.017 3.096   42.568 1.00 31.14  ?  702  ALA   A H    1 
ATOM   112  H  HA   . ALA   A 1 10  ? 64.553 4.876   40.384 1.00 33.04  ?  702  ALA   A HA   1 
ATOM   113  H  HB1  . ALA   A 1 10  ? 62.450 3.965   39.448 1.00 20.70  ?  702  ALA   A HB1  1 
ATOM   114  H  HB2  . ALA   A 1 10  ? 63.503 2.697   40.073 1.00 20.70  ?  702  ALA   A HB2  1 
ATOM   115  H  HB3  . ALA   A 1 10  ? 62.085 3.198   40.987 1.00 20.70  ?  702  ALA   A HB3  1 
ATOM   116  N  N    . LEU   A 1 11  ? 62.891 6.750   40.388 1.00 42.54  ?  703  LEU   A N    1 
ATOM   117  C  CA   . LEU   A 1 11  ? 62.101 7.962   40.503 1.00 34.53  ?  703  LEU   A CA   1 
ATOM   118  C  C    . LEU   A 1 11  ? 60.839 7.823   39.684 1.00 35.43  ?  703  LEU   A C    1 
ATOM   119  O  O    . LEU   A 1 11  ? 60.891 7.478   38.496 1.00 46.17  ?  703  LEU   A O    1 
ATOM   120  C  CB   . LEU   A 1 11  ? 62.847 9.173   39.961 1.00 29.92  ?  703  LEU   A CB   1 
ATOM   121  C  CG   . LEU   A 1 11  ? 64.170 9.486   40.645 1.00 49.12  ?  703  LEU   A CG   1 
ATOM   122  C  CD1  . LEU   A 1 11  ? 64.736 10.783  40.090 1.00 44.18  ?  703  LEU   A CD1  1 
ATOM   123  C  CD2  . LEU   A 1 11  ? 64.074 9.542   42.167 1.00 48.79  ?  703  LEU   A CD2  1 
ATOM   124  H  H    . LEU   A 1 11  ? 63.361 6.570   39.517 1.00 44.54  ?  703  LEU   A H    1 
ATOM   125  H  HA   . LEU   A 1 11  ? 61.842 8.164   41.539 1.00 36.53  ?  703  LEU   A HA   1 
ATOM   126  H  HB2  . LEU   A 1 11  ? 63.028 9.052   38.891 1.00 31.92  ?  703  LEU   A HB2  1 
ATOM   127  H  HB3  . LEU   A 1 11  ? 62.195 10.045  40.052 1.00 31.92  ?  703  LEU   A HB3  1 
ATOM   128  H  HG   . LEU   A 1 11  ? 64.874 8.689   40.399 1.00 51.12  ?  703  LEU   A HG   1 
ATOM   129  H  HD11 . LEU   A 1 11  ? 65.718 10.995  40.514 1.00 46.18  ?  703  LEU   A HD11 1 
ATOM   130  H  HD12 . LEU   A 1 11  ? 64.858 10.730  39.007 1.00 46.18  ?  703  LEU   A HD12 1 
ATOM   131  H  HD13 . LEU   A 1 11  ? 64.088 11.631  40.312 1.00 46.18  ?  703  LEU   A HD13 1 
ATOM   132  H  HD21 . LEU   A 1 11  ? 65.022 9.846   42.611 1.00 50.79  ?  703  LEU   A HD21 1 
ATOM   133  H  HD22 . LEU   A 1 11  ? 63.310 10.246  42.500 1.00 50.79  ?  703  LEU   A HD22 1 
ATOM   134  H  HD23 . LEU   A 1 11  ? 63.839 8.567   42.597 1.00 50.79  ?  703  LEU   A HD23 1 
ATOM   135  N  N    . LEU   A 1 12  ? 59.720 8.134   40.329 1.00 37.35  ?  704  LEU   A N    1 
ATOM   136  C  CA   . LEU   A 1 12  ? 58.442 8.213   39.641 1.00 40.91  ?  704  LEU   A CA   1 
ATOM   137  C  C    . LEU   A 1 12  ? 58.169 9.684   39.350 1.00 38.19  ?  704  LEU   A C    1 
ATOM   138  O  O    . LEU   A 1 12  ? 57.995 10.504  40.256 1.00 36.31  ?  704  LEU   A O    1 
ATOM   139  C  CB   . LEU   A 1 12  ? 57.367 7.632   40.554 1.00 35.90  ?  704  LEU   A CB   1 
ATOM   140  C  CG   . LEU   A 1 12  ? 55.953 7.535   39.991 1.00 41.86  ?  704  LEU   A CG   1 
ATOM   141  C  CD1  . LEU   A 1 12  ? 55.873 6.631   38.768 1.00 31.13  ?  704  LEU   A CD1  1 
ATOM   142  C  CD2  . LEU   A 1 12  ? 55.010 7.059   41.089 1.00 38.51  ?  704  LEU   A CD2  1 
ATOM   143  H  H    . LEU   A 1 12  ? 59.775 8.479   41.288 1.00 39.35  ?  704  LEU   A H    1 
ATOM   144  H  HA   . LEU   A 1 12  ? 58.458 7.639   38.713 1.00 42.91  ?  704  LEU   A HA   1 
ATOM   145  H  HB2  . LEU   A 1 12  ? 57.683 6.639   40.871 1.00 37.90  ?  704  LEU   A HB2  1 
ATOM   146  H  HB3  . LEU   A 1 12  ? 57.337 8.227   41.466 1.00 37.90  ?  704  LEU   A HB3  1 
ATOM   147  H  HG   . LEU   A 1 12  ? 55.616 8.530   39.694 1.00 43.86  ?  704  LEU   A HG   1 
ATOM   148  H  HD11 . LEU   A 1 12  ? 54.841 6.505   38.445 1.00 33.13  ?  704  LEU   A HD11 1 
ATOM   149  H  HD12 . LEU   A 1 12  ? 56.419 7.045   37.919 1.00 33.13  ?  704  LEU   A HD12 1 
ATOM   150  H  HD13 . LEU   A 1 12  ? 56.274 5.638   38.975 1.00 33.13  ?  704  LEU   A HD13 1 
ATOM   151  H  HD21 . LEU   A 1 12  ? 53.989 6.939   40.736 1.00 40.51  ?  704  LEU   A HD21 1 
ATOM   152  H  HD22 . LEU   A 1 12  ? 55.327 6.099   41.496 1.00 40.51  ?  704  LEU   A HD22 1 
ATOM   153  H  HD23 . LEU   A 1 12  ? 54.982 7.768   41.918 1.00 40.51  ?  704  LEU   A HD23 1 
ATOM   154  N  N    . ARG   A 1 13  ? 58.175 10.023  38.071 1.00 34.38  ?  705  ARG   A N    1 
ATOM   155  C  CA   . ARG   A 1 13  ? 57.944 11.392  37.647 1.00 33.71  ?  705  ARG   A CA   1 
ATOM   156  C  C    . ARG   A 1 13  ? 56.449 11.592  37.430 1.00 32.81  ?  705  ARG   A C    1 
ATOM   157  O  O    . ARG   A 1 13  ? 55.792 10.811  36.736 1.00 33.38  ?  705  ARG   A O    1 
ATOM   158  C  CB   . ARG   A 1 13  ? 58.705 11.612  36.338 1.00 33.65  ?  705  ARG   A CB   1 
ATOM   159  C  CG   . ARG   A 1 13  ? 58.821 13.058  35.867 1.00 55.30  ?  705  ARG   A CG   1 
ATOM   160  C  CD   . ARG   A 1 13  ? 59.795 13.199  34.699 1.00 60.15  ?  705  ARG   A CD   1 
ATOM   161  N  NE   . ARG   A 1 13  ? 59.852 14.586  34.198 1.00 74.34  ?  705  ARG   A NE   1 
ATOM   162  C  CZ   . ARG   A 1 13  ? 60.843 15.063  33.418 1.00 77.81  ?  705  ARG   A CZ   1 
ATOM   163  N  NH1  . ARG   A 1 13  ? 61.865 14.275  33.061 1.00 83.55  ?  705  ARG   A NH1  1 
ATOM   164  N  NH2  . ARG   A 1 13  ? 60.808 16.331  32.997 1.00 78.97  1  705  ARG   A NH2  1 
ATOM   165  H  H    . ARG   A 1 13  ? 58.324 9.307   37.357 1.00 36.38  ?  705  ARG   A H    1 
ATOM   166  H  HA   . ARG   A 1 13  ? 58.323 12.096  38.392 1.00 35.71  ?  705  ARG   A HA   1 
ATOM   167  H  HB2  . ARG   A 1 13  ? 59.715 11.220  36.466 1.00 35.65  ?  705  ARG   A HB2  1 
ATOM   168  H  HB3  . ARG   A 1 13  ? 58.259 11.010  35.544 1.00 35.65  ?  705  ARG   A HB3  1 
ATOM   169  H  HG2  . ARG   A 1 13  ? 57.836 13.435  35.589 1.00 57.30  ?  705  ARG   A HG2  1 
ATOM   170  H  HG3  . ARG   A 1 13  ? 59.167 13.681  36.692 1.00 57.30  ?  705  ARG   A HG3  1 
ATOM   171  H  HD2  . ARG   A 1 13  ? 60.788 12.889  35.023 1.00 62.15  ?  705  ARG   A HD2  1 
ATOM   172  H  HD3  . ARG   A 1 13  ? 59.502 12.544  33.877 1.00 62.15  ?  705  ARG   A HD3  1 
ATOM   173  H  HE   . ARG   A 1 13  ? 59.087 15.199  34.448 1.00 76.34  ?  705  ARG   A HE   1 
ATOM   174  H  HH11 . ARG   A 1 13  ? 61.898 13.317  33.373 1.00 85.55  ?  705  ARG   A HH11 1 
ATOM   175  H  HH12 . ARG   A 1 13  ? 62.603 14.639  32.475 1.00 85.55  ?  705  ARG   A HH12 1 
ATOM   176  H  HH21 . ARG   A 1 13  ? 60.042 16.933  33.262 1.00 80.97  ?  705  ARG   A HH21 1 
ATOM   177  H  HH22 . ARG   A 1 13  ? 61.545 16.690  32.403 1.00 80.97  ?  705  ARG   A HH22 1 
ATOM   178  N  N    . ILE   A 1 14  ? 55.916 12.649  38.023 1.00 33.50  ?  706  ILE   A N    1 
ATOM   179  C  CA   . ILE   A 1 14  ? 54.514 12.984  37.825 1.00 36.93  ?  706  ILE   A CA   1 
ATOM   180  C  C    . ILE   A 1 14  ? 54.478 14.196  36.911 1.00 36.06  ?  706  ILE   A C    1 
ATOM   181  O  O    . ILE   A 1 14  ? 55.143 15.206  37.157 1.00 38.42  ?  706  ILE   A O    1 
ATOM   182  C  CB   . ILE   A 1 14  ? 53.791 13.211  39.158 1.00 36.70  ?  706  ILE   A CB   1 
ATOM   183  C  CG1  . ILE   A 1 14  ? 53.882 11.947  40.018 1.00 39.43  ?  706  ILE   A CG1  1 
ATOM   184  C  CG2  . ILE   A 1 14  ? 52.330 13.628  38.952 1.00 34.49  ?  706  ILE   A CG2  1 
ATOM   185  C  CD1  . ILE   A 1 14  ? 53.340 12.111  41.415 1.00 64.48  ?  706  ILE   A CD1  1 
ATOM   186  H  H    . ILE   A 1 14  ? 56.482 13.273  38.576 1.00 35.50  ?  706  ILE   A H    1 
ATOM   187  H  HA   . ILE   A 1 14  ? 53.978 12.164  37.352 1.00 38.93  ?  706  ILE   A HA   1 
ATOM   188  H  HB   . ILE   A 1 14  ? 54.303 14.008  39.696 1.00 38.70  ?  706  ILE   A HB   1 
ATOM   189  H  HG12 . ILE   A 1 14  ? 53.375 11.116  39.531 1.00 41.43  ?  706  ILE   A HG12 1 
ATOM   190  H  HG13 . ILE   A 1 14  ? 54.922 11.636  40.126 1.00 41.43  ?  706  ILE   A HG13 1 
ATOM   191  H  HG21 . ILE   A 1 14  ? 51.812 13.790  39.897 1.00 36.49  ?  706  ILE   A HG21 1 
ATOM   192  H  HG22 . ILE   A 1 14  ? 52.243 14.570  38.410 1.00 36.49  ?  706  ILE   A HG22 1 
ATOM   193  H  HG23 . ILE   A 1 14  ? 51.773 12.879  38.389 1.00 36.49  ?  706  ILE   A HG23 1 
ATOM   194  H  HD11 . ILE   A 1 14  ? 53.655 11.265  42.018 1.00 66.48  ?  706  ILE   A HD11 1 
ATOM   195  H  HD12 . ILE   A 1 14  ? 53.742 13.009  41.882 1.00 66.48  ?  706  ILE   A HD12 1 
ATOM   196  H  HD13 . ILE   A 1 14  ? 52.253 12.157  41.443 1.00 66.48  ?  706  ILE   A HD13 1 
ATOM   197  N  N    . LEU   A 1 15  ? 53.722 14.045  35.840 1.00 34.75  ?  707  LEU   A N    1 
ATOM   198  C  CA   . LEU   A 1 15  ? 53.671 14.985  34.739 1.00 43.69  ?  707  LEU   A CA   1 
ATOM   199  C  C    . LEU   A 1 15  ? 52.326 15.702  34.745 1.00 43.61  ?  707  LEU   A C    1 
ATOM   200  O  O    . LEU   A 1 15  ? 51.287 15.122  35.083 1.00 43.80  ?  707  LEU   A O    1 
ATOM   201  C  CB   . LEU   A 1 15  ? 53.832 14.209  33.420 1.00 37.83  ?  707  LEU   A CB   1 
ATOM   202  C  CG   . LEU   A 1 15  ? 55.122 13.384  33.317 1.00 37.01  ?  707  LEU   A CG   1 
ATOM   203  C  CD1  . LEU   A 1 15  ? 55.078 12.420  32.152 1.00 51.15  ?  707  LEU   A CD1  1 
ATOM   204  C  CD2  . LEU   A 1 15  ? 56.358 14.256  33.230 1.00 40.79  ?  707  LEU   A CD2  1 
ATOM   205  H  H    . LEU   A 1 15  ? 53.146 13.205  35.761 1.00 36.75  ?  707  LEU   A H    1 
ATOM   206  H  HA   . LEU   A 1 15  ? 54.463 15.732  34.819 1.00 45.69  ?  707  LEU   A HA   1 
ATOM   207  H  HB2  . LEU   A 1 15  ? 52.977 13.539  33.303 1.00 39.83  ?  707  LEU   A HB2  1 
ATOM   208  H  HB3  . LEU   A 1 15  ? 53.776 14.902  32.578 1.00 39.83  ?  707  LEU   A HB3  1 
ATOM   209  H  HG   . LEU   A 1 15  ? 55.227 12.767  34.210 1.00 39.01  ?  707  LEU   A HG   1 
ATOM   210  H  HD11 . LEU   A 1 15  ? 54.365 11.627  32.368 1.00 53.15  ?  707  LEU   A HD11 1 
ATOM   211  H  HD12 . LEU   A 1 15  ? 54.795 12.913  31.221 1.00 53.15  ?  707  LEU   A HD12 1 
ATOM   212  H  HD13 . LEU   A 1 15  ? 56.042 11.935  31.991 1.00 53.15  ?  707  LEU   A HD13 1 
ATOM   213  H  HD21 . LEU   A 1 15  ? 57.258 13.648  33.149 1.00 42.79  ?  707  LEU   A HD21 1 
ATOM   214  H  HD22 . LEU   A 1 15  ? 56.317 14.901  32.354 1.00 42.79  ?  707  LEU   A HD22 1 
ATOM   215  H  HD23 . LEU   A 1 15  ? 56.472 14.895  34.106 1.00 42.79  ?  707  LEU   A HD23 1 
ATOM   216  N  N    . LYS   A 1 16  ? 52.336 16.958  34.314 1.00 53.27  ?  708  LYS   A N    1 
ATOM   217  C  CA   . LYS   A 1 16  ? 51.089 17.693  34.132 1.00 55.08  ?  708  LYS   A CA   1 
ATOM   218  C  C    . LYS   A 1 16  ? 50.425 17.278  32.828 1.00 46.83  ?  708  LYS   A C    1 
ATOM   219  O  O    . LYS   A 1 16  ? 51.091 17.107  31.806 1.00 54.71  ?  708  LYS   A O    1 
ATOM   220  C  CB   . LYS   A 1 16  ? 51.344 19.191  33.965 1.00 57.47  ?  708  LYS   A CB   1 
ATOM   221  C  CG   . LYS   A 1 16  ? 52.074 19.907  35.089 1.00 67.98  ?  708  LYS   A CG   1 
ATOM   222  C  CD   . LYS   A 1 16  ? 52.435 21.328  34.659 1.00 81.29  ?  708  LYS   A CD   1 
ATOM   223  C  CE   . LYS   A 1 16  ? 53.138 22.134  35.736 1.00 90.01  ?  708  LYS   A CE   1 
ATOM   224  N  NZ   . LYS   A 1 16  ? 53.512 23.471  35.250 1.00 93.28  1  708  LYS   A NZ   1 
ATOM   225  H  H    . LYS   A 1 16  ? 53.201 17.367  33.976 1.00 55.27  ?  708  LYS   A H    1 
ATOM   226  H  HA   . LYS   A 1 16  ? 50.425 17.528  34.984 1.00 57.08  ?  708  LYS   A HA   1 
ATOM   227  H  HB2  . LYS   A 1 16  ? 51.899 19.355  33.041 1.00 59.47  ?  708  LYS   A HB2  1 
ATOM   228  H  HB3  . LYS   A 1 16  ? 50.388 19.698  33.818 1.00 59.47  ?  708  LYS   A HB3  1 
ATOM   229  H  HG2  . LYS   A 1 16  ? 51.448 19.927  35.982 1.00 69.98  ?  708  LYS   A HG2  1 
ATOM   230  H  HG3  . LYS   A 1 16  ? 52.985 19.369  35.356 1.00 69.98  ?  708  LYS   A HG3  1 
ATOM   231  H  HD2  . LYS   A 1 16  ? 53.076 21.281  33.776 1.00 83.29  ?  708  LYS   A HD2  1 
ATOM   232  H  HD3  . LYS   A 1 16  ? 51.531 21.856  34.351 1.00 83.29  ?  708  LYS   A HD3  1 
ATOM   233  H  HE2  . LYS   A 1 16  ? 52.478 22.264  36.589 1.00 92.01  ?  708  LYS   A HE2  1 
ATOM   234  H  HE3  . LYS   A 1 16  ? 54.034 21.619  36.084 1.00 92.01  ?  708  LYS   A HE3  1 
ATOM   235  H  HZ1  . LYS   A 1 16  ? 53.980 23.978  35.986 1.00 95.28  ?  708  LYS   A HZ1  1 
ATOM   236  H  HZ2  . LYS   A 1 16  ? 54.137 23.392  34.454 1.00 95.28  ?  708  LYS   A HZ2  1 
ATOM   237  H  HZ3  . LYS   A 1 16  ? 52.684 23.975  34.970 1.00 95.28  ?  708  LYS   A HZ3  1 
ATOM   238  N  N    . GLU   A 1 17  ? 49.101 17.261  32.851 1.00 46.79  ?  709  GLU   A N    1 
ATOM   239  C  CA   . GLU   A 1 17  ? 48.231 17.122  31.681 1.00 49.50  ?  709  GLU   A CA   1 
ATOM   240  C  C    . GLU   A 1 17  ? 48.562 18.064  30.518 1.00 57.62  ?  709  GLU   A C    1 
ATOM   241  O  O    . GLU   A 1 17  ? 48.437 17.743  29.337 1.00 55.41  ?  709  GLU   A O    1 
ATOM   242  C  CB   . GLU   A 1 17  ? 46.792 17.269  32.199 1.00 54.56  ?  709  GLU   A CB   1 
ATOM   243  C  CG   . GLU   A 1 17  ? 45.613 17.408  31.226 1.00 72.16  ?  709  GLU   A CG   1 
ATOM   244  C  CD   . GLU   A 1 17  ? 45.163 16.043  30.750 1.00 84.42  ?  709  GLU   A CD   1 
ATOM   245  O  OE1  . GLU   A 1 17  ? 43.960 15.732  30.872 1.00 92.21  ?  709  GLU   A OE1  1 
ATOM   246  O  OE2  . GLU   A 1 17  ? 46.003 15.267  30.250 1.00 95.28  -1 709  GLU   A OE2  1 
ATOM   247  H  H    . GLU   A 1 17  ? 48.642 17.350  33.757 1.00 48.79  ?  709  GLU   A H    1 
ATOM   248  H  HA   . GLU   A 1 17  ? 48.357 16.107  31.300 1.00 51.50  ?  709  GLU   A HA   1 
ATOM   249  H  HB2  . GLU   A 1 17  ? 46.591 16.449  32.892 1.00 56.56  ?  709  GLU   A HB2  1 
ATOM   250  H  HB3  . GLU   A 1 17  ? 46.760 18.163  32.822 1.00 56.56  ?  709  GLU   A HB3  1 
ATOM   251  H  HG2  . GLU   A 1 17  ? 44.778 17.894  31.732 1.00 74.16  ?  709  GLU   A HG2  1 
ATOM   252  H  HG3  . GLU   A 1 17  ? 45.873 18.031  30.371 1.00 74.16  ?  709  GLU   A HG3  1 
ATOM   253  N  N    . THR   A 1 18  ? 49.026 19.249  30.884 1.00 59.28  ?  710  THR   A N    1 
ATOM   254  C  CA   . THR   A 1 18  ? 49.390 20.289  29.937 1.00 56.70  ?  710  THR   A CA   1 
ATOM   255  C  C    . THR   A 1 18  ? 50.773 20.119  29.299 1.00 64.81  ?  710  THR   A C    1 
ATOM   256  O  O    . THR   A 1 18  ? 51.113 20.856  28.370 1.00 59.80  ?  710  THR   A O    1 
ATOM   257  C  CB   . THR   A 1 18  ? 49.300 21.648  30.661 1.00 63.27  ?  710  THR   A CB   1 
ATOM   258  O  OG1  . THR   A 1 18  ? 50.176 21.780  31.781 1.00 62.55  ?  710  THR   A OG1  1 
ATOM   259  C  CG2  . THR   A 1 18  ? 47.896 21.957  31.159 1.00 49.81  ?  710  THR   A CG2  1 
ATOM   260  H  H    . THR   A 1 18  ? 49.136 19.458  31.864 1.00 61.28  ?  710  THR   A H    1 
ATOM   261  H  HA   . THR   A 1 18  ? 48.665 20.304  29.123 1.00 58.70  ?  710  THR   A HA   1 
ATOM   262  H  HB   . THR   A 1 18  ? 49.570 22.433  29.950 1.00 65.27  ?  710  THR   A HB   1 
ATOM   263  H  HG1  . THR   A 1 18  ? 51.069 21.818  31.460 1.00 64.55  ?  710  THR   A HG1  1 
ATOM   264  H  HG21 . THR   A 1 18  ? 47.842 22.966  31.565 1.00 51.81  ?  710  THR   A HG21 1 
ATOM   265  H  HG22 . THR   A 1 18  ? 47.170 21.890  30.348 1.00 51.81  ?  710  THR   A HG22 1 
ATOM   266  H  HG23 . THR   A 1 18  ? 47.580 21.269  31.943 1.00 51.81  ?  710  THR   A HG23 1 
ATOM   267  N  N    . GLU   A 1 19  ? 51.577 19.162  29.773 1.00 63.35  ?  711  GLU   A N    1 
ATOM   268  C  CA   . GLU   A 1 19  ? 52.884 18.923  29.159 1.00 46.61  ?  711  GLU   A CA   1 
ATOM   269  C  C    . GLU   A 1 19  ? 52.771 18.071  27.899 1.00 42.70  ?  711  GLU   A C    1 
ATOM   270  O  O    . GLU   A 1 19  ? 53.746 17.951  27.162 1.00 47.07  ?  711  GLU   A O    1 
ATOM   271  C  CB   . GLU   A 1 19  ? 53.813 18.164  30.109 1.00 57.35  ?  711  GLU   A CB   1 
ATOM   272  C  CG   . GLU   A 1 19  ? 54.425 19.012  31.212 1.00 61.03  ?  711  GLU   A CG   1 
ATOM   273  C  CD   . GLU   A 1 19  ? 55.184 18.123  32.178 1.00 72.22  ?  711  GLU   A CD   1 
ATOM   274  O  OE1  . GLU   A 1 19  ? 56.163 17.472  31.758 1.00 74.85  ?  711  GLU   A OE1  1 
ATOM   275  O  OE2  . GLU   A 1 19  ? 54.811 18.070  33.367 1.00 82.16  -1 711  GLU   A OE2  1 
ATOM   276  H  H    . GLU   A 1 19  ? 51.257 18.523  30.497 1.00 65.35  ?  711  GLU   A H    1 
ATOM   277  H  HA   . GLU   A 1 19  ? 53.368 19.863  28.883 1.00 48.61  ?  711  GLU   A HA   1 
ATOM   278  H  HB2  . GLU   A 1 19  ? 53.305 17.291  30.521 1.00 59.35  ?  711  GLU   A HB2  1 
ATOM   279  H  HB3  . GLU   A 1 19  ? 54.661 17.772  29.547 1.00 59.35  ?  711  GLU   A HB3  1 
ATOM   280  H  HG2  . GLU   A 1 19  ? 55.106 19.750  30.788 1.00 63.03  ?  711  GLU   A HG2  1 
ATOM   281  H  HG3  . GLU   A 1 19  ? 53.659 19.569  31.746 1.00 63.03  ?  711  GLU   A HG3  1 
ATOM   282  N  N    . PHE   A 1 20  ? 51.621 17.467  27.631 1.00 35.70  ?  712  PHE   A N    1 
ATOM   283  C  CA   . PHE   A 1 20  ? 51.532 16.475  26.570 1.00 43.12  ?  712  PHE   A CA   1 
ATOM   284  C  C    . PHE   A 1 20  ? 50.215 16.564  25.826 1.00 47.09  ?  712  PHE   A C    1 
ATOM   285  O  O    . PHE   A 1 20  ? 49.233 17.103  26.333 1.00 59.62  ?  712  PHE   A O    1 
ATOM   286  C  CB   . PHE   A 1 20  ? 51.906 15.077  27.071 1.00 47.33  ?  712  PHE   A CB   1 
ATOM   287  C  CG   . PHE   A 1 20  ? 50.992 14.526  28.146 1.00 39.53  ?  712  PHE   A CG   1 
ATOM   288  C  CD1  . PHE   A 1 20  ? 49.814 13.842  27.787 1.00 43.59  ?  712  PHE   A CD1  1 
ATOM   289  C  CD2  . PHE   A 1 20  ? 51.314 14.706  29.507 1.00 40.65  ?  712  PHE   A CD2  1 
ATOM   290  C  CE1  . PHE   A 1 20  ? 48.955 13.345  28.785 1.00 43.65  ?  712  PHE   A CE1  1 
ATOM   291  C  CE2  . PHE   A 1 20  ? 50.453 14.209  30.504 1.00 40.33  ?  712  PHE   A CE2  1 
ATOM   292  C  CZ   . PHE   A 1 20  ? 49.272 13.531  30.143 1.00 42.36  ?  712  PHE   A CZ   1 
ATOM   293  H  H    . PHE   A 1 20  ? 50.802 17.602  28.211 1.00 37.70  ?  712  PHE   A H    1 
ATOM   294  H  HA   . PHE   A 1 20  ? 52.252 16.746  25.801 1.00 45.12  ?  712  PHE   A HA   1 
ATOM   295  H  HB2  . PHE   A 1 20  ? 51.919 14.374  26.238 1.00 49.33  ?  712  PHE   A HB2  1 
ATOM   296  H  HB3  . PHE   A 1 20  ? 52.921 15.079  27.464 1.00 49.33  ?  712  PHE   A HB3  1 
ATOM   297  H  HD1  . PHE   A 1 20  ? 49.564 13.704  26.745 1.00 45.59  ?  712  PHE   A HD1  1 
ATOM   298  H  HD2  . PHE   A 1 20  ? 52.215 15.231  29.787 1.00 42.65  ?  712  PHE   A HD2  1 
ATOM   299  H  HE1  . PHE   A 1 20  ? 48.050 12.826  28.509 1.00 45.65  ?  712  PHE   A HE1  1 
ATOM   300  H  HE2  . PHE   A 1 20  ? 50.696 14.353  31.547 1.00 42.33  ?  712  PHE   A HE2  1 
ATOM   301  H  HZ   . PHE   A 1 20  ? 48.609 13.155  30.908 1.00 44.36  ?  712  PHE   A HZ   1 
ATOM   302  N  N    . LYS   A 1 21  ? 50.196 16.035  24.610 1.00 50.45  ?  713  LYS   A N    1 
ATOM   303  C  CA   . LYS   A 1 21  ? 48.985 16.024  23.805 1.00 57.54  ?  713  LYS   A CA   1 
ATOM   304  C  C    . LYS   A 1 21  ? 48.792 14.691  23.119 1.00 54.45  ?  713  LYS   A C    1 
ATOM   305  O  O    . LYS   A 1 21  ? 49.744 14.122  22.582 1.00 63.99  ?  713  LYS   A O    1 
ATOM   306  C  CB   . LYS   A 1 21  ? 48.883 17.219  22.865 1.00 64.83  ?  713  LYS   A CB   1 
ATOM   307  C  CG   . LYS   A 1 21  ? 50.031 17.387  21.871 1.00 73.40  ?  713  LYS   A CG   1 
ATOM   308  C  CD   . LYS   A 1 21  ? 49.687 18.404  20.791 1.00 81.08  ?  713  LYS   A CD   1 
ATOM   309  C  CE   . LYS   A 1 21  ? 50.811 18.641  19.797 1.00 79.82  ?  713  LYS   A CE   1 
ATOM   310  N  NZ   . LYS   A 1 21  ? 50.406 19.606  18.759 1.00 89.10  1  713  LYS   A NZ   1 
ATOM   311  H  H    . LYS   A 1 21  ? 51.043 15.624  24.230 1.00 52.45  ?  713  LYS   A H    1 
ATOM   312  H  HA   . LYS   A 1 21  ? 48.123 16.111  24.472 1.00 59.54  ?  713  LYS   A HA   1 
ATOM   313  H  HB2  . LYS   A 1 21  ? 47.945 17.132  22.313 1.00 66.83  ?  713  LYS   A HB2  1 
ATOM   314  H  HB3  . LYS   A 1 21  ? 48.786 18.130  23.456 1.00 66.83  ?  713  LYS   A HB3  1 
ATOM   315  H  HG2  . LYS   A 1 21  ? 50.932 17.691  22.406 1.00 75.40  ?  713  LYS   A HG2  1 
ATOM   316  H  HG3  . LYS   A 1 21  ? 50.265 16.434  21.394 1.00 75.40  ?  713  LYS   A HG3  1 
ATOM   317  H  HD2  . LYS   A 1 21  ? 48.801 18.065  20.251 1.00 83.08  ?  713  LYS   A HD2  1 
ATOM   318  H  HD3  . LYS   A 1 21  ? 49.416 19.352  21.260 1.00 83.08  ?  713  LYS   A HD3  1 
ATOM   319  H  HE2  . LYS   A 1 21  ? 51.694 19.026  20.308 1.00 81.82  ?  713  LYS   A HE2  1 
ATOM   320  H  HE3  . LYS   A 1 21  ? 51.100 17.707  19.314 1.00 81.82  ?  713  LYS   A HE3  1 
ATOM   321  H  HZ1  . LYS   A 1 21  ? 51.171 19.760  18.120 1.00 91.10  ?  713  LYS   A HZ1  1 
ATOM   322  H  HZ2  . LYS   A 1 21  ? 49.614 19.242  18.250 1.00 91.10  ?  713  LYS   A HZ2  1 
ATOM   323  H  HZ3  . LYS   A 1 21  ? 50.150 20.481  19.192 1.00 91.10  ?  713  LYS   A HZ3  1 
ATOM   324  N  N    . LYS   A 1 22  ? 47.549 14.220  23.135 1.00 45.97  ?  714  LYS   A N    1 
ATOM   325  C  CA   . LYS   A 1 22  ? 47.147 13.012  22.426 1.00 56.40  ?  714  LYS   A CA   1 
ATOM   326  C  C    . LYS   A 1 22  ? 46.816 13.397  20.986 1.00 59.09  ?  714  LYS   A C    1 
ATOM   327  O  O    . LYS   A 1 22  ? 46.119 14.383  20.743 1.00 63.74  ?  714  LYS   A O    1 
ATOM   328  C  CB   . LYS   A 1 22  ? 45.882 12.434  23.077 1.00 52.40  ?  714  LYS   A CB   1 
ATOM   329  C  CG   . LYS   A 1 22  ? 46.049 12.054  24.553 1.00 60.64  ?  714  LYS   A CG   1 
ATOM   330  C  CD   . LYS   A 1 22  ? 44.740 11.993  25.337 1.00 72.05  ?  714  LYS   A CD   1 
ATOM   331  C  CE   . LYS   A 1 22  ? 44.971 11.862  26.840 1.00 82.08  ?  714  LYS   A CE   1 
ATOM   332  N  NZ   . LYS   A 1 22  ? 43.737 12.044  27.623 1.00 80.18  1  714  LYS   A NZ   1 
ATOM   333  H  H    . LYS   A 1 22  ? 46.818 14.788  23.533 1.00 47.97  ?  714  LYS   A H    1 
ATOM   334  H  HA   . LYS   A 1 22  ? 47.944 12.264  22.452 1.00 58.40  ?  714  LYS   A HA   1 
ATOM   335  H  HB2  . LYS   A 1 22  ? 45.078 13.167  22.988 1.00 54.40  ?  714  LYS   A HB2  1 
ATOM   336  H  HB3  . LYS   A 1 22  ? 45.539 11.560  22.521 1.00 54.40  ?  714  LYS   A HB3  1 
ATOM   337  H  HG2  . LYS   A 1 22  ? 46.575 11.102  24.631 1.00 62.64  ?  714  LYS   A HG2  1 
ATOM   338  H  HG3  . LYS   A 1 22  ? 46.691 12.781  25.050 1.00 62.64  ?  714  LYS   A HG3  1 
ATOM   339  H  HD2  . LYS   A 1 22  ? 44.173 12.907  25.153 1.00 74.05  ?  714  LYS   A HD2  1 
ATOM   340  H  HD3  . LYS   A 1 22  ? 44.120 11.171  24.976 1.00 74.05  ?  714  LYS   A HD3  1 
ATOM   341  H  HE2  . LYS   A 1 22  ? 45.411 10.894  27.083 1.00 84.08  ?  714  LYS   A HE2  1 
ATOM   342  H  HE3  . LYS   A 1 22  ? 45.674 12.625  27.176 1.00 84.08  ?  714  LYS   A HE3  1 
ATOM   343  H  HZ1  . LYS   A 1 22  ? 43.997 12.279  28.571 1.00 82.18  ?  714  LYS   A HZ1  1 
ATOM   344  H  HZ2  . LYS   A 1 22  ? 43.176 12.787  27.237 1.00 82.18  ?  714  LYS   A HZ2  1 
ATOM   345  H  HZ3  . LYS   A 1 22  ? 43.196 11.188  27.675 1.00 82.18  ?  714  LYS   A HZ3  1 
ATOM   346  N  N    . ILE   A 1 23  ? 47.342 12.633  20.040 1.00 65.09  ?  715  ILE   A N    1 
ATOM   347  C  CA   . ILE   A 1 23  ? 47.257 12.977  18.623 1.00 62.43  ?  715  ILE   A CA   1 
ATOM   348  C  C    . ILE   A 1 23  ? 46.367 11.981  17.887 1.00 61.33  ?  715  ILE   A C    1 
ATOM   349  O  O    . ILE   A 1 23  ? 45.535 12.370  17.067 1.00 69.52  ?  715  ILE   A O    1 
ATOM   350  C  CB   . ILE   A 1 23  ? 48.681 13.080  18.025 1.00 66.16  ?  715  ILE   A CB   1 
ATOM   351  C  CG1  . ILE   A 1 23  ? 49.454 14.256  18.636 1.00 50.51  ?  715  ILE   A CG1  1 
ATOM   352  C  CG2  . ILE   A 1 23  ? 48.709 13.166  16.497 1.00 66.19  ?  715  ILE   A CG2  1 
ATOM   353  C  CD1  . ILE   A 1 23  ? 50.960 14.207  18.420 1.00 58.95  ?  715  ILE   A CD1  1 
ATOM   354  H  H    . ILE   A 1 23  ? 47.937 11.847  20.299 1.00 67.09  ?  715  ILE   A H    1 
ATOM   355  H  HA   . ILE   A 1 23  ? 46.785 13.951  18.474 1.00 64.43  ?  715  ILE   A HA   1 
ATOM   356  H  HB   . ILE   A 1 23  ? 49.211 12.164  18.292 1.00 68.16  ?  715  ILE   A HB   1 
ATOM   357  H  HG12 . ILE   A 1 23  ? 49.059 15.196  18.249 1.00 52.51  ?  715  ILE   A HG12 1 
ATOM   358  H  HG13 . ILE   A 1 23  ? 49.295 14.299  19.713 1.00 52.51  ?  715  ILE   A HG13 1 
ATOM   359  H  HG21 . ILE   A 1 23  ? 49.722 13.249  16.108 1.00 68.19  ?  715  ILE   A HG21 1 
ATOM   360  H  HG22 . ILE   A 1 23  ? 48.284 12.282  16.023 1.00 68.19  ?  715  ILE   A HG22 1 
ATOM   361  H  HG23 . ILE   A 1 23  ? 48.150 14.033  16.142 1.00 68.19  ?  715  ILE   A HG23 1 
ATOM   362  H  HD11 . ILE   A 1 23  ? 51.427 15.072  18.888 1.00 60.95  ?  715  ILE   A HD11 1 
ATOM   363  H  HD12 . ILE   A 1 23  ? 51.397 13.311  18.862 1.00 60.95  ?  715  ILE   A HD12 1 
ATOM   364  H  HD13 . ILE   A 1 23  ? 51.236 14.231  17.367 1.00 60.95  ?  715  ILE   A HD13 1 
ATOM   365  N  N    . LYS   A 1 24  ? 46.539 10.698  18.179 1.00 61.06  ?  716  LYS   A N    1 
ATOM   366  C  CA   . LYS   A 1 24  ? 45.758 9.628   17.563 1.00 57.08  ?  716  LYS   A CA   1 
ATOM   367  C  C    . LYS   A 1 24  ? 45.584 8.518   18.573 1.00 53.13  ?  716  LYS   A C    1 
ATOM   368  O  O    . LYS   A 1 24  ? 46.371 8.420   19.514 1.00 62.19  ?  716  LYS   A O    1 
ATOM   369  C  CB   . LYS   A 1 24  ? 46.382 9.120   16.260 1.00 66.88  ?  716  LYS   A CB   1 
ATOM   370  C  CG   . LYS   A 1 24  ? 45.966 9.877   15.004 1.00 81.63  ?  716  LYS   A CG   1 
ATOM   371  C  CD   . LYS   A 1 24  ? 46.591 9.290   13.744 1.00 93.45  ?  716  LYS   A CD   1 
ATOM   372  C  CE   . LYS   A 1 24  ? 46.199 10.038  12.476 1.00 91.87  ?  716  LYS   A CE   1 
ATOM   373  N  NZ   . LYS   A 1 24  ? 46.874 9.475   11.295 1.00 95.53  1  716  LYS   A NZ   1 
ATOM   374  H  H    . LYS   A 1 24  ? 47.179 10.434  18.918 1.00 63.06  ?  716  LYS   A H    1 
ATOM   375  H  HA   . LYS   A 1 24  ? 44.748 9.991   17.357 1.00 59.08  ?  716  LYS   A HA   1 
ATOM   376  H  HB2  . LYS   A 1 24  ? 47.469 9.125   16.352 1.00 68.88  ?  716  LYS   A HB2  1 
ATOM   377  H  HB3  . LYS   A 1 24  ? 46.117 8.071   16.108 1.00 68.88  ?  716  LYS   A HB3  1 
ATOM   378  H  HG2  . LYS   A 1 24  ? 44.878 9.861   14.913 1.00 83.63  ?  716  LYS   A HG2  1 
ATOM   379  H  HG3  . LYS   A 1 24  ? 46.253 10.924  15.088 1.00 83.63  ?  716  LYS   A HG3  1 
ATOM   380  H  HD2  . LYS   A 1 24  ? 47.677 9.298   13.847 1.00 95.45  ?  716  LYS   A HD2  1 
ATOM   381  H  HD3  . LYS   A 1 24  ? 46.300 8.242   13.647 1.00 95.45  ?  716  LYS   A HD3  1 
ATOM   382  H  HE2  . LYS   A 1 24  ? 45.121 9.988   12.320 1.00 93.87  ?  716  LYS   A HE2  1 
ATOM   383  H  HE3  . LYS   A 1 24  ? 46.464 11.092  12.558 1.00 93.87  ?  716  LYS   A HE3  1 
ATOM   384  H  HZ1  . LYS   A 1 24  ? 46.619 10.004  10.474 1.00 97.53  ?  716  LYS   A HZ1  1 
ATOM   385  H  HZ2  . LYS   A 1 24  ? 47.874 9.520   11.422 1.00 97.53  ?  716  LYS   A HZ2  1 
ATOM   386  H  HZ3  . LYS   A 1 24  ? 46.597 8.513   11.171 1.00 97.53  ?  716  LYS   A HZ3  1 
ATOM   387  N  N    . VAL   A 1 25  ? 44.598 7.657   18.365 1.00 52.91  ?  717  VAL   A N    1 
ATOM   388  C  CA   . VAL   A 1 25  ? 44.489 6.434   19.158 1.00 61.11  ?  717  VAL   A CA   1 
ATOM   389  C  C    . VAL   A 1 25  ? 45.331 5.356   18.487 1.00 70.07  ?  717  VAL   A C    1 
ATOM   390  O  O    . VAL   A 1 25  ? 45.274 5.183   17.268 1.00 81.57  ?  717  VAL   A O    1 
ATOM   391  C  CB   . VAL   A 1 25  ? 43.018 5.989   19.250 1.00 64.92  ?  717  VAL   A CB   1 
ATOM   392  C  CG1  . VAL   A 1 25  ? 42.814 4.631   19.924 1.00 69.83  ?  717  VAL   A CG1  1 
ATOM   393  C  CG2  . VAL   A 1 25  ? 42.179 7.028   19.983 1.00 63.06  ?  717  VAL   A CG2  1 
ATOM   394  H  H    . VAL   A 1 25  ? 44.029 7.735   17.536 1.00 54.91  ?  717  VAL   A H    1 
ATOM   395  H  HA   . VAL   A 1 25  ? 44.839 6.595   20.178 1.00 63.11  ?  717  VAL   A HA   1 
ATOM   396  H  HB   . VAL   A 1 25  ? 42.620 5.906   18.237 1.00 66.92  ?  717  VAL   A HB   1 
ATOM   397  H  HG11 . VAL   A 1 25  ? 41.760 4.435   20.123 1.00 71.83  ?  717  VAL   A HG11 1 
ATOM   398  H  HG12 . VAL   A 1 25  ? 43.160 3.814   19.290 1.00 71.83  ?  717  VAL   A HG12 1 
ATOM   399  H  HG13 . VAL   A 1 25  ? 43.346 4.571   20.874 1.00 71.83  ?  717  VAL   A HG13 1 
ATOM   400  H  HG21 . VAL   A 1 25  ? 41.123 6.753   19.989 1.00 65.06  ?  717  VAL   A HG21 1 
ATOM   401  H  HG22 . VAL   A 1 25  ? 42.495 7.113   21.022 1.00 65.06  ?  717  VAL   A HG22 1 
ATOM   402  H  HG23 . VAL   A 1 25  ? 42.249 8.017   19.531 1.00 65.06  ?  717  VAL   A HG23 1 
ATOM   403  N  N    . LEU   A 1 26  ? 46.102 4.636   19.292 1.00 72.35  ?  718  LEU   A N    1 
ATOM   404  C  CA   . LEU   A 1 26  ? 46.863 3.486   18.807 1.00 65.70  ?  718  LEU   A CA   1 
ATOM   405  C  C    . LEU   A 1 26  ? 46.164 2.168   19.120 1.00 69.79  ?  718  LEU   A C    1 
ATOM   406  O  O    . LEU   A 1 26  ? 46.479 1.140   18.520 1.00 76.88  ?  718  LEU   A O    1 
ATOM   407  C  CB   . LEU   A 1 26  ? 48.236 3.439   19.480 1.00 67.23  ?  718  LEU   A CB   1 
ATOM   408  C  CG   . LEU   A 1 26  ? 49.165 4.595   19.130 1.00 53.73  ?  718  LEU   A CG   1 
ATOM   409  C  CD1  . LEU   A 1 26  ? 50.327 4.676   20.104 1.00 50.53  ?  718  LEU   A CD1  1 
ATOM   410  C  CD2  . LEU   A 1 26  ? 49.685 4.508   17.706 1.00 53.79  ?  718  LEU   A CD2  1 
ATOM   411  H  H    . LEU   A 1 26  ? 46.074 4.794   20.299 1.00 74.35  ?  718  LEU   A H    1 
ATOM   412  H  HA   . LEU   A 1 26  ? 47.002 3.516   17.725 1.00 67.70  ?  718  LEU   A HA   1 
ATOM   413  H  HB2  . LEU   A 1 26  ? 48.095 3.407   20.561 1.00 69.23  ?  718  LEU   A HB2  1 
ATOM   414  H  HB3  . LEU   A 1 26  ? 48.745 2.506   19.227 1.00 69.23  ?  718  LEU   A HB3  1 
ATOM   415  H  HG   . LEU   A 1 26  ? 48.599 5.520   19.222 1.00 55.73  ?  718  LEU   A HG   1 
ATOM   416  H  HD11 . LEU   A 1 26  ? 51.022 5.465   19.826 1.00 52.53  ?  718  LEU   A HD11 1 
ATOM   417  H  HD12 . LEU   A 1 26  ? 49.983 4.906   21.110 1.00 52.53  ?  718  LEU   A HD12 1 
ATOM   418  H  HD13 . LEU   A 1 26  ? 50.878 3.741   20.154 1.00 52.53  ?  718  LEU   A HD13 1 
ATOM   419  H  HD21 . LEU   A 1 26  ? 50.384 5.312   17.478 1.00 55.79  ?  718  LEU   A HD21 1 
ATOM   420  H  HD22 . LEU   A 1 26  ? 50.219 3.577   17.537 1.00 55.79  ?  718  LEU   A HD22 1 
ATOM   421  H  HD23 . LEU   A 1 26  ? 48.880 4.568   16.974 1.00 55.79  ?  718  LEU   A HD23 1 
ATOM   422  N  N    . GLY   A 1 27  ? 45.209 2.183   20.040 1.00 75.38  ?  719  GLY   A N    1 
ATOM   423  C  CA   . GLY   A 1 27  ? 44.548 0.952   20.423 1.00 74.17  ?  719  GLY   A CA   1 
ATOM   424  C  C    . GLY   A 1 27  ? 43.776 1.118   21.707 1.00 82.58  ?  719  GLY   A C    1 
ATOM   425  O  O    . GLY   A 1 27  ? 43.973 2.081   22.454 1.00 83.73  ?  719  GLY   A O    1 
ATOM   426  H  H    . GLY   A 1 27  ? 45.025 3.015   20.586 1.00 77.38  ?  719  GLY   A H    1 
ATOM   427  H  HA2  . GLY   A 1 27  ? 43.881 0.632   19.621 1.00 76.17  ?  719  GLY   A HA2  1 
ATOM   428  H  HA3  . GLY   A 1 27  ? 45.280 0.156   20.580 1.00 76.17  ?  719  GLY   A HA3  1 
ATOM   429  N  N    . SER   A 1 28  ? 42.876 0.179   21.956 1.00 91.01  ?  720  SER   A N    1 
ATOM   430  C  CA   . SER   A 1 28  ? 42.051 0.214   23.156 1.00 93.95  ?  720  SER   A CA   1 
ATOM   431  C  C    . SER   A 1 28  ? 41.582 -1.180  23.525 1.00 95.66  ?  720  SER   A C    1 
ATOM   432  O  O    . SER   A 1 28  ? 41.294 -2.003  22.652 1.00 92.98  ?  720  SER   A O    1 
ATOM   433  C  CB   . SER   A 1 28  ? 40.922 1.250   23.087 1.00 92.79  ?  720  SER   A CB   1 
ATOM   434  O  OG   . SER   A 1 28  ? 39.983 1.019   22.044 1.00 93.34  ?  720  SER   A OG   1 
ATOM   435  H  H    . SER   A 1 28  ? 42.725 -0.598  21.328 1.00 93.01  ?  720  SER   A H    1 
ATOM   436  H  HA   . SER   A 1 28  ? 42.714 0.509   23.972 1.00 95.95  ?  720  SER   A HA   1 
ATOM   437  H  HB2  . SER   A 1 28  ? 40.372 1.257   24.028 1.00 94.79  ?  720  SER   A HB2  1 
ATOM   438  H  HB3  . SER   A 1 28  ? 41.330 2.252   22.966 1.00 94.79  ?  720  SER   A HB3  1 
ATOM   439  H  HG   . SER   A 1 28  ? 39.633 0.141   22.140 1.00 95.34  ?  720  SER   A HG   1 
ATOM   440  N  N    . GLY   A 1 29  ? 41.496 -1.433  24.819 1.00 100.59 ?  721  GLY   A N    1 
ATOM   441  C  CA   . GLY   A 1 29  ? 40.788 -2.600  25.310 1.00 105.18 ?  721  GLY   A CA   1 
ATOM   442  C  C    . GLY   A 1 29  ? 40.029 -2.245  26.566 1.00 107.50 ?  721  GLY   A C    1 
ATOM   443  O  O    . GLY   A 1 29  ? 39.784 -1.073  26.863 1.00 106.02 ?  721  GLY   A O    1 
ATOM   444  H  H    . GLY   A 1 29  ? 41.662 -0.681  25.486 1.00 102.59 ?  721  GLY   A H    1 
ATOM   445  H  HA2  . GLY   A 1 29  ? 40.060 -2.978  24.589 1.00 107.18 ?  721  GLY   A HA2  1 
ATOM   446  H  HA3  . GLY   A 1 29  ? 41.498 -3.403  25.502 1.00 107.18 ?  721  GLY   A HA3  1 
ATOM   447  N  N    . ALA   A 1 30  ? 39.719 -3.266  27.359 1.00 108.33 ?  722  ALA   A N    1 
ATOM   448  C  CA   . ALA   A 1 30  ? 39.093 -3.034  28.664 1.00 109.00 ?  722  ALA   A CA   1 
ATOM   449  C  C    . ALA   A 1 30  ? 40.032 -2.413  29.699 1.00 109.64 ?  722  ALA   A C    1 
ATOM   450  O  O    . ALA   A 1 30  ? 39.597 -1.870  30.713 1.00 106.22 ?  722  ALA   A O    1 
ATOM   451  C  CB   . ALA   A 1 30  ? 38.573 -4.347  29.220 1.00 106.51 ?  722  ALA   A CB   1 
ATOM   452  H  H    . ALA   A 1 30  ? 39.932 -4.212  27.078 1.00 110.33 ?  722  ALA   A H    1 
ATOM   453  H  HA   . ALA   A 1 30  ? 38.244 -2.359  28.539 1.00 111.00 ?  722  ALA   A HA   1 
ATOM   454  H  HB1  . ALA   A 1 30  ? 38.047 -4.194  30.164 1.00 108.51 ?  722  ALA   A HB1  1 
ATOM   455  H  HB2  . ALA   A 1 30  ? 37.869 -4.817  28.533 1.00 108.51 ?  722  ALA   A HB2  1 
ATOM   456  H  HB3  . ALA   A 1 30  ? 39.381 -5.056  29.408 1.00 108.51 ?  722  ALA   A HB3  1 
ATOM   457  N  N    . PHE   A 1 31  ? 41.326 -2.474  29.409 1.00 110.72 ?  723  PHE   A N    1 
ATOM   458  C  CA   . PHE   A 1 31  ? 42.344 -1.778  30.184 1.00 107.34 ?  723  PHE   A CA   1 
ATOM   459  C  C    . PHE   A 1 31  ? 42.377 -0.268  29.953 1.00 104.34 ?  723  PHE   A C    1 
ATOM   460  O  O    . PHE   A 1 31  ? 43.053 0.446   30.694 1.00 110.44 ?  723  PHE   A O    1 
ATOM   461  C  CB   . PHE   A 1 31  ? 43.712 -2.363  29.822 1.00 109.28 ?  723  PHE   A CB   1 
ATOM   462  C  CG   . PHE   A 1 31  ? 44.079 -2.305  28.340 1.00 111.92 ?  723  PHE   A CG   1 
ATOM   463  C  CD1  . PHE   A 1 31  ? 44.622 -1.123  27.792 1.00 108.91 ?  723  PHE   A CD1  1 
ATOM   464  C  CD2  . PHE   A 1 31  ? 43.871 -3.430  27.514 1.00 114.49 ?  723  PHE   A CD2  1 
ATOM   465  C  CE1  . PHE   A 1 31  ? 44.949 -1.066  26.426 1.00 112.56 ?  723  PHE   A CE1  1 
ATOM   466  C  CE2  . PHE   A 1 31  ? 44.203 -3.370  26.146 1.00 114.36 ?  723  PHE   A CE2  1 
ATOM   467  C  CZ   . PHE   A 1 31  ? 44.741 -2.187  25.603 1.00 116.25 ?  723  PHE   A CZ   1 
ATOM   468  H  H    . PHE   A 1 31  ? 41.606 -2.899  28.539 1.00 112.72 ?  723  PHE   A H    1 
ATOM   469  H  HA   . PHE   A 1 31  ? 42.166 -1.943  31.249 1.00 109.34 ?  723  PHE   A HA   1 
ATOM   470  H  HB2  . PHE   A 1 31  ? 44.495 -1.860  30.393 1.00 111.28 ?  723  PHE   A HB2  1 
ATOM   471  H  HB3  . PHE   A 1 31  ? 43.753 -3.403  30.150 1.00 111.28 ?  723  PHE   A HB3  1 
ATOM   472  H  HD1  . PHE   A 1 31  ? 44.782 -0.259  28.420 1.00 110.91 ?  723  PHE   A HD1  1 
ATOM   473  H  HD2  . PHE   A 1 31  ? 43.457 -4.338  27.929 1.00 116.49 ?  723  PHE   A HD2  1 
ATOM   474  H  HE1  . PHE   A 1 31  ? 45.360 -0.161  26.011 1.00 114.56 ?  723  PHE   A HE1  1 
ATOM   475  H  HE2  . PHE   A 1 31  ? 44.044 -4.231  25.513 1.00 116.36 ?  723  PHE   A HE2  1 
ATOM   476  H  HZ   . PHE   A 1 31  ? 44.994 -2.142  24.553 1.00 118.25 ?  723  PHE   A HZ   1 
ATOM   477  N  N    . GLY   A 1 32  ? 41.693 0.200   28.911 1.00 97.94  ?  724  GLY   A N    1 
ATOM   478  C  CA   . GLY   A 1 32  ? 41.685 1.607   28.579 1.00 89.23  ?  724  GLY   A CA   1 
ATOM   479  C  C    . GLY   A 1 32  ? 42.101 1.896   27.154 1.00 86.63  ?  724  GLY   A C    1 
ATOM   480  O  O    . GLY   A 1 32  ? 41.730 1.168   26.230 1.00 83.01  ?  724  GLY   A O    1 
ATOM   481  H  H    . GLY   A 1 32  ? 41.154 -0.421  28.319 1.00 99.94  ?  724  GLY   A H    1 
ATOM   482  H  HA2  . GLY   A 1 32  ? 40.651 1.917   28.685 1.00 91.23  ?  724  GLY   A HA2  1 
ATOM   483  H  HA3  . GLY   A 1 32  ? 42.260 2.206   29.278 1.00 91.23  ?  724  GLY   A HA3  1 
ATOM   484  N  N    . THR   A 1 33  ? 42.826 2.991   26.954 1.00 84.70  ?  725  THR   A N    1 
ATOM   485  C  CA   . THR   A 1 33  ? 43.125 3.483   25.605 1.00 77.63  ?  725  THR   A CA   1 
ATOM   486  C  C    . THR   A 1 33  ? 44.576 3.921   25.536 1.00 74.75  ?  725  THR   A C    1 
ATOM   487  O  O    . THR   A 1 33  ? 45.033 4.664   26.407 1.00 75.74  ?  725  THR   A O    1 
ATOM   488  C  CB   . THR   A 1 33  ? 42.144 4.579   25.156 1.00 80.13  ?  725  THR   A CB   1 
ATOM   489  O  OG1  . THR   A 1 33  ? 40.803 4.103   25.169 1.00 82.86  ?  725  THR   A OG1  1 
ATOM   490  C  CG2  . THR   A 1 33  ? 42.391 5.107   23.751 1.00 85.69  ?  725  THR   A CG2  1 
ATOM   491  H  H    . THR   A 1 33  ? 43.156 3.535   27.751 1.00 86.70  ?  725  THR   A H    1 
ATOM   492  H  HA   . THR   A 1 33  ? 43.037 2.666   24.889 1.00 79.63  ?  725  THR   A HA   1 
ATOM   493  H  HB   . THR   A 1 33  ? 42.216 5.422   25.845 1.00 82.13  ?  725  THR   A HB   1 
ATOM   494  H  HG1  . THR   A 1 33  ? 40.827 3.157   25.094 1.00 84.86  ?  725  THR   A HG1  1 
ATOM   495  H  HG21 . THR   A 1 33  ? 41.637 5.842   23.468 1.00 87.69  ?  725  THR   A HG21 1 
ATOM   496  H  HG22 . THR   A 1 33  ? 43.356 5.610   23.669 1.00 87.69  ?  725  THR   A HG22 1 
ATOM   497  H  HG23 . THR   A 1 33  ? 42.373 4.311   23.008 1.00 87.69  ?  725  THR   A HG23 1 
ATOM   498  N  N    . VAL   A 1 34  ? 45.274 3.469   24.495 1.00 70.12  ?  726  VAL   A N    1 
ATOM   499  C  CA   . VAL   A 1 34  ? 46.629 3.916   24.212 1.00 54.61  ?  726  VAL   A CA   1 
ATOM   500  C  C    . VAL   A 1 34  ? 46.530 4.942   23.095 1.00 53.98  ?  726  VAL   A C    1 
ATOM   501  O  O    . VAL   A 1 34  ? 45.977 4.673   22.022 1.00 49.18  ?  726  VAL   A O    1 
ATOM   502  C  CB   . VAL   A 1 34  ? 47.533 2.751   23.770 1.00 49.89  ?  726  VAL   A CB   1 
ATOM   503  C  CG1  . VAL   A 1 34  ? 48.997 3.161   23.649 1.00 45.45  ?  726  VAL   A CG1  1 
ATOM   504  C  CG2  . VAL   A 1 34  ? 47.444 1.564   24.714 1.00 48.60  ?  726  VAL   A CG2  1 
ATOM   505  H  H    . VAL   A 1 34  ? 44.805 2.937   23.762 1.00 72.12  ?  726  VAL   A H    1 
ATOM   506  H  HA   . VAL   A 1 34  ? 47.081 4.355   25.097 1.00 56.61  ?  726  VAL   A HA   1 
ATOM   507  H  HB   . VAL   A 1 34  ? 47.205 2.399   22.789 1.00 51.89  ?  726  VAL   A HB   1 
ATOM   508  H  HG11 . VAL   A 1 34  ? 49.620 2.330   23.315 1.00 47.45  ?  726  VAL   A HG11 1 
ATOM   509  H  HG12 . VAL   A 1 34  ? 49.135 3.966   22.931 1.00 47.45  ?  726  VAL   A HG12 1 
ATOM   510  H  HG13 . VAL   A 1 34  ? 49.392 3.507   24.605 1.00 47.45  ?  726  VAL   A HG13 1 
ATOM   511  H  HG21 . VAL   A 1 34  ? 48.144 0.781   24.427 1.00 50.60  ?  726  VAL   A HG21 1 
ATOM   512  H  HG22 . VAL   A 1 34  ? 47.660 1.848   25.745 1.00 50.60  ?  726  VAL   A HG22 1 
ATOM   513  H  HG23 . VAL   A 1 34  ? 46.451 1.122   24.682 1.00 50.60  ?  726  VAL   A HG23 1 
ATOM   514  N  N    . TYR   A 1 35  ? 47.073 6.116   23.360 1.00 51.46  ?  727  TYR   A N    1 
ATOM   515  C  CA   . TYR   A 1 35  ? 47.135 7.174   22.368 1.00 55.60  ?  727  TYR   A CA   1 
ATOM   516  C  C    . TYR   A 1 35  ? 48.572 7.379   21.931 1.00 54.89  ?  727  TYR   A C    1 
ATOM   517  O  O    . TYR   A 1 35  ? 49.500 7.269   22.731 1.00 52.00  ?  727  TYR   A O    1 
ATOM   518  C  CB   . TYR   A 1 35  ? 46.647 8.494   22.948 1.00 56.83  ?  727  TYR   A CB   1 
ATOM   519  C  CG   . TYR   A 1 35  ? 45.242 8.498   23.527 1.00 70.61  ?  727  TYR   A CG   1 
ATOM   520  C  CD1  . TYR   A 1 35  ? 45.046 8.241   24.899 1.00 71.24  ?  727  TYR   A CD1  1 
ATOM   521  C  CD2  . TYR   A 1 35  ? 44.134 8.769   22.698 1.00 77.58  ?  727  TYR   A CD2  1 
ATOM   522  C  CE1  . TYR   A 1 35  ? 43.750 8.262   25.442 1.00 82.80  ?  727  TYR   A CE1  1 
ATOM   523  C  CE2  . TYR   A 1 35  ? 42.834 8.787   23.245 1.00 77.91  ?  727  TYR   A CE2  1 
ATOM   524  C  CZ   . TYR   A 1 35  ? 42.644 8.536   24.617 1.00 81.99  ?  727  TYR   A CZ   1 
ATOM   525  O  OH   . TYR   A 1 35  ? 41.389 8.564   25.148 1.00 93.58  ?  727  TYR   A OH   1 
ATOM   526  H  H    . TYR   A 1 35  ? 47.466 6.285   24.284 1.00 53.46  ?  727  TYR   A H    1 
ATOM   527  H  HA   . TYR   A 1 35  ? 46.529 6.940   21.499 1.00 57.60  ?  727  TYR   A HA   1 
ATOM   528  H  HB2  . TYR   A 1 35  ? 47.328 8.836   23.726 1.00 58.83  ?  727  TYR   A HB2  1 
ATOM   529  H  HB3  . TYR   A 1 35  ? 46.691 9.267   22.177 1.00 58.83  ?  727  TYR   A HB3  1 
ATOM   530  H  HD1  . TYR   A 1 35  ? 45.893 8.033   25.537 1.00 73.24  ?  727  TYR   A HD1  1 
ATOM   531  H  HD2  . TYR   A 1 35  ? 44.279 8.967   21.645 1.00 79.58  ?  727  TYR   A HD2  1 
ATOM   532  H  HE1  . TYR   A 1 35  ? 43.607 8.070   26.491 1.00 84.80  ?  727  TYR   A HE1  1 
ATOM   533  H  HE2  . TYR   A 1 35  ? 41.984 8.999   22.612 1.00 79.91  ?  727  TYR   A HE2  1 
ATOM   534  H  HH   . TYR   A 1 35  ? 41.385 8.460   26.093 1.00 95.58  ?  727  TYR   A HH   1 
ATOM   535  N  N    . LYS   A 1 36  ? 48.734 7.760   20.674 1.00 47.24  ?  728  LYS   A N    1 
ATOM   536  C  CA   . LYS   A 1 36  ? 49.984 8.317   20.183 1.00 45.13  ?  728  LYS   A CA   1 
ATOM   537  C  C    . LYS   A 1 36  ? 49.991 9.779   20.585 1.00 43.44  ?  728  LYS   A C    1 
ATOM   538  O  O    . LYS   A 1 36  ? 48.991 10.475  20.378 1.00 46.14  ?  728  LYS   A O    1 
ATOM   539  C  CB   . LYS   A 1 36  ? 49.974 8.266   18.652 1.00 53.08  ?  728  LYS   A CB   1 
ATOM   540  C  CG   . LYS   A 1 36  ? 51.268 8.683   17.951 1.00 59.82  ?  728  LYS   A CG   1 
ATOM   541  C  CD   . LYS   A 1 36  ? 51.028 9.054   16.492 1.00 66.62  ?  728  LYS   A CD   1 
ATOM   542  C  CE   . LYS   A 1 36  ? 52.310 9.351   15.724 1.00 69.51  ?  728  LYS   A CE   1 
ATOM   543  N  NZ   . LYS   A 1 36  ? 52.016 9.872   14.377 1.00 83.90  1  728  LYS   A NZ   1 
ATOM   544  H  H    . LYS   A 1 36  ? 47.890 7.949   20.135 1.00 49.24  ?  728  LYS   A H    1 
ATOM   545  H  HA   . LYS   A 1 36  ? 50.847 7.781   20.586 1.00 47.13  ?  728  LYS   A HA   1 
ATOM   546  H  HB2  . LYS   A 1 36  ? 49.721 7.263   18.322 1.00 55.08  ?  728  LYS   A HB2  1 
ATOM   547  H  HB3  . LYS   A 1 36  ? 49.154 8.886   18.283 1.00 55.08  ?  728  LYS   A HB3  1 
ATOM   548  H  HG2  . LYS   A 1 36  ? 51.724 9.538   18.451 1.00 61.82  ?  728  LYS   A HG2  1 
ATOM   549  H  HG3  . LYS   A 1 36  ? 51.992 7.871   18.025 1.00 61.82  ?  728  LYS   A HG3  1 
ATOM   550  H  HD2  . LYS   A 1 36  ? 50.485 8.250   15.992 1.00 68.62  ?  728  LYS   A HD2  1 
ATOM   551  H  HD3  . LYS   A 1 36  ? 50.377 9.930   16.458 1.00 68.62  ?  728  LYS   A HD3  1 
ATOM   552  H  HE2  . LYS   A 1 36  ? 52.922 10.080  16.255 1.00 71.51  ?  728  LYS   A HE2  1 
ATOM   553  H  HE3  . LYS   A 1 36  ? 52.904 8.441   15.624 1.00 71.51  ?  728  LYS   A HE3  1 
ATOM   554  H  HZ1  . LYS   A 1 36  ? 52.874 9.982   13.857 1.00 85.90  ?  728  LYS   A HZ1  1 
ATOM   555  H  HZ2  . LYS   A 1 36  ? 51.413 9.228   13.888 1.00 85.90  ?  728  LYS   A HZ2  1 
ATOM   556  H  HZ3  . LYS   A 1 36  ? 51.556 10.767  14.455 1.00 85.90  ?  728  LYS   A HZ3  1 
ATOM   557  N  N    . GLY   A 1 37  ? 51.081 10.232  21.174 1.00 37.45  ?  729  GLY   A N    1 
ATOM   558  C  CA   . GLY   A 1 37  ? 51.147 11.614  21.591 1.00 34.14  ?  729  GLY   A CA   1 
ATOM   559  C  C    . GLY   A 1 37  ? 52.523 12.214  21.504 1.00 40.66  ?  729  GLY   A C    1 
ATOM   560  O  O    . GLY   A 1 37  ? 53.485 11.602  21.036 1.00 40.16  ?  729  GLY   A O    1 
ATOM   561  H  H    . GLY   A 1 37  ? 51.873 9.623   21.385 1.00 39.45  ?  729  GLY   A H    1 
ATOM   562  H  HA2  . GLY   A 1 37  ? 50.501 12.255  20.988 1.00 36.14  ?  729  GLY   A HA2  1 
ATOM   563  H  HA3  . GLY   A 1 37  ? 50.795 11.677  22.619 1.00 36.14  ?  729  GLY   A HA3  1 
ATOM   564  N  N    . LEU   A 1 38  ? 52.594 13.431  22.012 1.00 34.66  ?  730  LEU   A N    1 
ATOM   565  C  CA   . LEU   A 1 38  ? 53.832 14.176  22.078 1.00 44.11  ?  730  LEU   A CA   1 
ATOM   566  C  C    . LEU   A 1 38  ? 53.918 14.769  23.471 1.00 42.58  ?  730  LEU   A C    1 
ATOM   567  O  O    . LEU   A 1 38  ? 52.955 15.370  23.946 1.00 43.55  ?  730  LEU   A O    1 
ATOM   568  C  CB   . LEU   A 1 38  ? 53.825 15.226  20.967 1.00 52.24  ?  730  LEU   A CB   1 
ATOM   569  C  CG   . LEU   A 1 38  ? 55.167 15.684  20.422 1.00 58.40  ?  730  LEU   A CG   1 
ATOM   570  C  CD1  . LEU   A 1 38  ? 55.906 14.566  19.706 1.00 43.06  ?  730  LEU   A CD1  1 
ATOM   571  C  CD2  . LEU   A 1 38  ? 54.949 16.840  19.460 1.00 59.97  ?  730  LEU   A CD2  1 
ATOM   572  H  H    . LEU   A 1 38  ? 51.759 13.855  22.405 1.00 36.66  ?  730  LEU   A H    1 
ATOM   573  H  HA   . LEU   A 1 38  ? 54.680 13.507  21.945 1.00 46.11  ?  730  LEU   A HA   1 
ATOM   574  H  HB2  . LEU   A 1 38  ? 53.264 14.834  20.121 1.00 54.24  ?  730  LEU   A HB2  1 
ATOM   575  H  HB3  . LEU   A 1 38  ? 53.254 16.093  21.306 1.00 54.24  ?  730  LEU   A HB3  1 
ATOM   576  H  HG   . LEU   A 1 38  ? 55.788 16.040  21.247 1.00 60.40  ?  730  LEU   A HG   1 
ATOM   577  H  HD11 . LEU   A 1 38  ? 56.786 14.938  19.181 1.00 45.06  ?  730  LEU   A HD11 1 
ATOM   578  H  HD12 . LEU   A 1 38  ? 56.263 13.819  20.406 1.00 45.06  ?  730  LEU   A HD12 1 
ATOM   579  H  HD13 . LEU   A 1 38  ? 55.273 14.064  18.973 1.00 45.06  ?  730  LEU   A HD13 1 
ATOM   580  H  HD21 . LEU   A 1 38  ? 55.890 17.166  19.024 1.00 61.97  ?  730  LEU   A HD21 1 
ATOM   581  H  HD22 . LEU   A 1 38  ? 54.289 16.558  18.638 1.00 61.97  ?  730  LEU   A HD22 1 
ATOM   582  H  HD23 . LEU   A 1 38  ? 54.505 17.697  19.967 1.00 61.97  ?  730  LEU   A HD23 1 
ATOM   583  N  N    . TRP   A 1 39  ? 55.047 14.577  24.125 1.00 41.41  ?  731  TRP   A N    1 
ATOM   584  C  CA   . TRP   A 1 39  ? 55.308 15.141  25.438 1.00 42.98  ?  731  TRP   A CA   1 
ATOM   585  C  C    . TRP   A 1 39  ? 56.348 16.233  25.277 1.00 45.78  ?  731  TRP   A C    1 
ATOM   586  O  O    . TRP   A 1 39  ? 57.375 16.051  24.622 1.00 41.66  ?  731  TRP   A O    1 
ATOM   587  C  CB   . TRP   A 1 39  ? 55.809 14.039  26.370 1.00 41.04  ?  731  TRP   A CB   1 
ATOM   588  C  CG   . TRP   A 1 39  ? 56.350 14.426  27.715 1.00 42.76  ?  731  TRP   A CG   1 
ATOM   589  C  CD1  . TRP   A 1 39  ? 55.859 15.404  28.508 1.00 47.55  ?  731  TRP   A CD1  1 
ATOM   590  C  CD2  . TRP   A 1 39  ? 57.487 13.864  28.434 1.00 46.79  ?  731  TRP   A CD2  1 
ATOM   591  N  NE1  . TRP   A 1 39  ? 56.617 15.495  29.655 1.00 45.75  ?  731  TRP   A NE1  1 
ATOM   592  C  CE2  . TRP   A 1 39  ? 57.639 14.572  29.667 1.00 41.74  ?  731  TRP   A CE2  1 
ATOM   593  C  CE3  . TRP   A 1 39  ? 58.418 12.826  28.176 1.00 45.60  ?  731  TRP   A CE3  1 
ATOM   594  C  CZ2  . TRP   A 1 39  ? 58.652 14.278  30.583 1.00 44.15  ?  731  TRP   A CZ2  1 
ATOM   595  C  CZ3  . TRP   A 1 39  ? 59.444 12.523  29.100 1.00 43.88  ?  731  TRP   A CZ3  1 
ATOM   596  C  CH2  . TRP   A 1 39  ? 59.560 13.249  30.300 1.00 36.72  ?  731  TRP   A CH2  1 
ATOM   597  H  H    . TRP   A 1 39  ? 55.802 14.047  23.688 1.00 43.41  ?  731  TRP   A H    1 
ATOM   598  H  HA   . TRP   A 1 39  ? 54.413 15.579  25.877 1.00 44.98  ?  731  TRP   A HA   1 
ATOM   599  H  HB2  . TRP   A 1 39  ? 55.017 13.309  26.537 1.00 43.04  ?  731  TRP   A HB2  1 
ATOM   600  H  HB3  . TRP   A 1 39  ? 56.609 13.496  25.867 1.00 43.04  ?  731  TRP   A HB3  1 
ATOM   601  H  HD1  . TRP   A 1 39  ? 55.009 16.017  28.260 1.00 49.55  ?  731  TRP   A HD1  1 
ATOM   602  H  HE1  . TRP   A 1 39  ? 56.422 16.174  30.391 1.00 47.75  ?  731  TRP   A HE1  1 
ATOM   603  H  HE3  . TRP   A 1 39  ? 58.343 12.261  27.258 1.00 47.60  ?  731  TRP   A HE3  1 
ATOM   604  H  HZ2  . TRP   A 1 39  ? 58.735 14.839  31.501 1.00 46.15  ?  731  TRP   A HZ2  1 
ATOM   605  H  HZ3  . TRP   A 1 39  ? 60.145 11.730  28.883 1.00 45.88  ?  731  TRP   A HZ3  1 
ATOM   606  H  HH2  . TRP   A 1 39  ? 60.346 13.013  31.000 1.00 38.72  ?  731  TRP   A HH2  1 
ATOM   607  N  N    . ILE   A 1 40  ? 56.054 17.381  25.857 1.00 47.64  ?  732  ILE   A N    1 
ATOM   608  C  CA   . ILE   A 1 40  ? 56.930 18.531  25.825 1.00 56.21  ?  732  ILE   A CA   1 
ATOM   609  C  C    . ILE   A 1 40  ? 57.195 18.896  27.283 1.00 63.45  ?  732  ILE   A C    1 
ATOM   610  O  O    . ILE   A 1 40  ? 56.358 19.568  27.896 1.00 65.66  ?  732  ILE   A O    1 
ATOM   611  C  CB   . ILE   A 1 40  ? 56.269 19.642  24.994 1.00 55.58  ?  732  ILE   A CB   1 
ATOM   612  C  CG1  . ILE   A 1 40  ? 56.137 19.251  23.517 1.00 56.62  ?  732  ILE   A CG1  1 
ATOM   613  C  CG2  . ILE   A 1 40  ? 57.014 20.972  25.091 1.00 61.33  ?  732  ILE   A CG2  1 
ATOM   614  C  CD1  . ILE   A 1 40  ? 54.900 19.803  22.829 1.00 54.20  ?  732  ILE   A CD1  1 
ATOM   615  H  H    . ILE   A 1 40  ? 55.191 17.495  26.390 1.00 49.64  ?  732  ILE   A H    1 
ATOM   616  H  HA   . ILE   A 1 40  ? 57.871 18.317  25.326 1.00 58.21  ?  732  ILE   A HA   1 
ATOM   617  H  HB   . ILE   A 1 40  ? 55.268 19.800  25.400 1.00 57.58  ?  732  ILE   A HB   1 
ATOM   618  H  HG12 . ILE   A 1 40  ? 57.035 19.581  22.996 1.00 58.62  ?  732  ILE   A HG12 1 
ATOM   619  H  HG13 . ILE   A 1 40  ? 56.117 18.172  23.382 1.00 58.62  ?  732  ILE   A HG13 1 
ATOM   620  H  HG21 . ILE   A 1 40  ? 56.565 21.724  24.443 1.00 63.33  ?  732  ILE   A HG21 1 
ATOM   621  H  HG22 . ILE   A 1 40  ? 56.991 21.386  26.100 1.00 63.33  ?  732  ILE   A HG22 1 
ATOM   622  H  HG23 . ILE   A 1 40  ? 58.061 20.870  24.804 1.00 63.33  ?  732  ILE   A HG23 1 
ATOM   623  H  HD11 . ILE   A 1 40  ? 54.867 19.501  21.784 1.00 56.20  ?  732  ILE   A HD11 1 
ATOM   624  H  HD12 . ILE   A 1 40  ? 53.991 19.435  23.306 1.00 56.20  ?  732  ILE   A HD12 1 
ATOM   625  H  HD13 . ILE   A 1 40  ? 54.877 20.892  22.864 1.00 56.20  ?  732  ILE   A HD13 1 
ATOM   626  N  N    . PRO   A 1 41  ? 58.300 18.428  27.887 1.00 68.72  ?  733  PRO   A N    1 
ATOM   627  C  CA   . PRO   A 1 41  ? 58.583 18.712  29.288 1.00 70.44  ?  733  PRO   A CA   1 
ATOM   628  C  C    . PRO   A 1 41  ? 58.816 20.190  29.600 1.00 80.95  ?  733  PRO   A C    1 
ATOM   629  O  O    . PRO   A 1 41  ? 59.244 20.976  28.751 1.00 75.15  ?  733  PRO   A O    1 
ATOM   630  C  CB   . PRO   A 1 41  ? 59.762 17.824  29.649 1.00 70.81  ?  733  PRO   A CB   1 
ATOM   631  C  CG   . PRO   A 1 41  ? 60.360 17.319  28.330 1.00 69.77  ?  733  PRO   A CG   1 
ATOM   632  C  CD   . PRO   A 1 41  ? 59.291 17.551  27.261 1.00 66.00  ?  733  PRO   A CD   1 
ATOM   633  H  HA   . PRO   A 1 41  ? 57.716 18.386  29.864 1.00 72.44  ?  733  PRO   A HA   1 
ATOM   634  H  HB2  . PRO   A 1 41  ? 60.511 18.323  30.265 1.00 72.81  ?  733  PRO   A HB2  1 
ATOM   635  H  HB3  . PRO   A 1 41  ? 59.404 16.972  30.225 1.00 72.81  ?  733  PRO   A HB3  1 
ATOM   636  H  HG2  . PRO   A 1 41  ? 61.253 17.892  28.084 1.00 71.77  ?  733  PRO   A HG2  1 
ATOM   637  H  HG3  . PRO   A 1 41  ? 60.661 16.272  28.391 1.00 71.77  ?  733  PRO   A HG3  1 
ATOM   638  H  HD2  . PRO   A 1 41  ? 59.743 18.000  26.376 1.00 68.00  ?  733  PRO   A HD2  1 
ATOM   639  H  HD3  . PRO   A 1 41  ? 58.824 16.607  26.977 1.00 68.00  ?  733  PRO   A HD3  1 
ATOM   640  N  N    . GLU   A 1 42  ? 58.514 20.554  30.843 1.00 92.79  ?  734  GLU   A N    1 
ATOM   641  C  CA   . GLU   A 1 42  ? 58.424 21.952  31.260 1.00 96.55  ?  734  GLU   A CA   1 
ATOM   642  C  C    . GLU   A 1 42  ? 59.733 22.721  31.140 1.00 93.93  ?  734  GLU   A C    1 
ATOM   643  O  O    . GLU   A 1 42  ? 60.672 22.507  31.910 1.00 100.12 ?  734  GLU   A O    1 
ATOM   644  C  CB   . GLU   A 1 42  ? 57.973 22.022  32.720 1.00 103.09 ?  734  GLU   A CB   1 
ATOM   645  C  CG   . GLU   A 1 42  ? 56.557 21.524  33.000 1.00 117.07 ?  734  GLU   A CG   1 
ATOM   646  C  CD   . GLU   A 1 42  ? 55.547 22.548  32.531 1.00 127.56 ?  734  GLU   A CD   1 
ATOM   647  O  OE1  . GLU   A 1 42  ? 55.466 23.635  33.141 1.00 127.92 ?  734  GLU   A OE1  1 
ATOM   648  O  OE2  . GLU   A 1 42  ? 54.821 22.277  31.554 1.00 134.26 -1 734  GLU   A OE2  1 
ATOM   649  H  H    . GLU   A 1 42  ? 58.175 19.853  31.484 1.00 94.79  ?  734  GLU   A H    1 
ATOM   650  H  HA   . GLU   A 1 42  ? 57.676 22.440  30.632 1.00 98.55  ?  734  GLU   A HA   1 
ATOM   651  H  HB2  . GLU   A 1 42  ? 58.665 21.441  33.333 1.00 105.09 ?  734  GLU   A HB2  1 
ATOM   652  H  HB3  . GLU   A 1 42  ? 58.072 23.045  33.091 1.00 105.09 ?  734  GLU   A HB3  1 
ATOM   653  H  HG2  . GLU   A 1 42  ? 56.377 20.574  32.507 1.00 119.07 ?  734  GLU   A HG2  1 
ATOM   654  H  HG3  . GLU   A 1 42  ? 56.415 21.362  34.068 1.00 119.07 ?  734  GLU   A HG3  1 
ATOM   655  N  N    . GLY   A 1 43  ? 59.801 23.602  30.151 1.00 88.25  ?  735  GLY   A N    1 
ATOM   656  C  CA   . GLY   A 1 43  ? 60.968 24.469  30.030 1.00 83.83  ?  735  GLY   A CA   1 
ATOM   657  C  C    . GLY   A 1 43  ? 62.068 23.913  29.149 1.00 87.18  ?  735  GLY   A C    1 
ATOM   658  O  O    . GLY   A 1 43  ? 63.026 24.611  28.812 1.00 90.51  ?  735  GLY   A O    1 
ATOM   659  H  H    . GLY   A 1 43  ? 59.058 23.659  29.470 1.00 90.25  ?  735  GLY   A H    1 
ATOM   660  H  HA2  . GLY   A 1 43  ? 60.635 25.405  29.582 1.00 85.83  ?  735  GLY   A HA2  1 
ATOM   661  H  HA3  . GLY   A 1 43  ? 61.388 24.740  31.000 1.00 85.83  ?  735  GLY   A HA3  1 
ATOM   662  N  N    . GLU   A 1 44  ? 61.925 22.646  28.792 1.00 84.02  ?  736  GLU   A N    1 
ATOM   663  C  CA   . GLU   A 1 44  ? 62.866 21.967  27.934 1.00 79.63  ?  736  GLU   A CA   1 
ATOM   664  C  C    . GLU   A 1 44  ? 62.417 22.207  26.507 1.00 83.83  ?  736  GLU   A C    1 
ATOM   665  O  O    . GLU   A 1 44  ? 61.237 22.060  26.171 1.00 90.92  ?  736  GLU   A O    1 
ATOM   666  C  CB   . GLU   A 1 44  ? 62.790 20.469  28.219 1.00 85.69  ?  736  GLU   A CB   1 
ATOM   667  C  CG   . GLU   A 1 44  ? 63.302 20.066  29.609 1.00 86.95  ?  736  GLU   A CG   1 
ATOM   668  C  CD   . GLU   A 1 44  ? 64.775 19.714  29.540 1.00 101.79 ?  736  GLU   A CD   1 
ATOM   669  O  OE1  . GLU   A 1 44  ? 65.556 20.489  28.951 1.00 108.95 ?  736  GLU   A OE1  1 
ATOM   670  O  OE2  . GLU   A 1 44  ? 65.166 18.655  30.074 1.00 100.46 -1 736  GLU   A OE2  1 
ATOM   671  H  H    . GLU   A 1 44  ? 61.059 22.167  29.015 1.00 86.02  ?  736  GLU   A H    1 
ATOM   672  H  HA   . GLU   A 1 44  ? 63.884 22.331  28.087 1.00 81.63  ?  736  GLU   A HA   1 
ATOM   673  H  HB2  . GLU   A 1 44  ? 61.751 20.146  28.126 1.00 87.69  ?  736  GLU   A HB2  1 
ATOM   674  H  HB3  . GLU   A 1 44  ? 63.323 19.913  27.446 1.00 87.69  ?  736  GLU   A HB3  1 
ATOM   675  H  HG2  . GLU   A 1 44  ? 63.152 20.870  30.331 1.00 88.95  ?  736  GLU   A HG2  1 
ATOM   676  H  HG3  . GLU   A 1 44  ? 62.734 19.215  29.979 1.00 88.95  ?  736  GLU   A HG3  1 
ATOM   677  N  N    . LYS   A 1 45  ? 63.368 22.554  25.653 1.00 76.54  ?  737  LYS   A N    1 
ATOM   678  C  CA   . LYS   A 1 45  ? 63.063 22.766  24.244 1.00 70.17  ?  737  LYS   A CA   1 
ATOM   679  C  C    . LYS   A 1 45  ? 63.143 21.417  23.526 1.00 69.21  ?  737  LYS   A C    1 
ATOM   680  O  O    . LYS   A 1 45  ? 64.078 21.123  22.781 1.00 68.45  ?  737  LYS   A O    1 
ATOM   681  C  CB   . LYS   A 1 45  ? 64.057 23.789  23.695 1.00 72.56  ?  737  LYS   A CB   1 
ATOM   682  C  CG   . LYS   A 1 45  ? 63.633 24.457  22.392 1.00 77.85  ?  737  LYS   A CG   1 
ATOM   683  C  CD   . LYS   A 1 45  ? 64.612 25.550  21.976 1.00 87.81  ?  737  LYS   A CD   1 
ATOM   684  C  CE   . LYS   A 1 45  ? 64.269 26.234  20.659 1.00 85.36  ?  737  LYS   A CE   1 
ATOM   685  N  NZ   . LYS   A 1 45  ? 64.534 25.366  19.498 1.00 92.08  1  737  LYS   A NZ   1 
ATOM   686  H  H    . LYS   A 1 45  ? 64.324 22.620  25.965 1.00 78.54  ?  737  LYS   A H    1 
ATOM   687  H  HA   . LYS   A 1 45  ? 62.057 23.175  24.122 1.00 72.17  ?  737  LYS   A HA   1 
ATOM   688  H  HB2  . LYS   A 1 45  ? 64.180 24.579  24.438 1.00 74.56  ?  737  LYS   A HB2  1 
ATOM   689  H  HB3  . LYS   A 1 45  ? 65.048 23.345  23.583 1.00 74.56  ?  737  LYS   A HB3  1 
ATOM   690  H  HG2  . LYS   A 1 45  ? 63.556 23.704  21.608 1.00 79.85  ?  737  LYS   A HG2  1 
ATOM   691  H  HG3  . LYS   A 1 45  ? 62.638 24.889  22.507 1.00 79.85  ?  737  LYS   A HG3  1 
ATOM   692  H  HD2  . LYS   A 1 45  ? 64.640 26.309  22.759 1.00 89.81  ?  737  LYS   A HD2  1 
ATOM   693  H  HD3  . LYS   A 1 45  ? 65.623 25.144  21.921 1.00 89.81  ?  737  LYS   A HD3  1 
ATOM   694  H  HE2  . LYS   A 1 45  ? 63.230 26.567  20.646 1.00 87.36  ?  737  LYS   A HE2  1 
ATOM   695  H  HE3  . LYS   A 1 45  ? 64.886 27.127  20.551 1.00 87.36  ?  737  LYS   A HE3  1 
ATOM   696  H  HZ1  . LYS   A 1 45  ? 63.877 24.593  19.463 1.00 94.08  ?  737  LYS   A HZ1  1 
ATOM   697  H  HZ2  . LYS   A 1 45  ? 64.457 25.902  18.647 1.00 94.08  ?  737  LYS   A HZ2  1 
ATOM   698  H  HZ3  . LYS   A 1 45  ? 65.461 24.974  19.564 1.00 94.08  ?  737  LYS   A HZ3  1 
ATOM   699  N  N    . VAL   A 1 46  ? 62.186 20.559  23.855 1.00 60.41  ?  738  VAL   A N    1 
ATOM   700  C  CA   . VAL   A 1 46  ? 62.225 19.143  23.534 1.00 53.40  ?  738  VAL   A CA   1 
ATOM   701  C  C    . VAL   A 1 46  ? 60.809 18.683  23.205 1.00 45.95  ?  738  VAL   A C    1 
ATOM   702  O  O    . VAL   A 1 46  ? 59.856 19.080  23.873 1.00 47.65  ?  738  VAL   A O    1 
ATOM   703  C  CB   . VAL   A 1 46  ? 62.928 18.352  24.661 1.00 61.43  ?  738  VAL   A CB   1 
ATOM   704  C  CG1  . VAL   A 1 46  ? 62.708 16.856  24.591 1.00 80.61  ?  738  VAL   A CG1  1 
ATOM   705  C  CG2  . VAL   A 1 46  ? 64.420 18.640  24.765 1.00 63.47  ?  738  VAL   A CG2  1 
ATOM   706  H  H    . VAL   A 1 46  ? 61.451 20.867  24.486 1.00 62.41  ?  738  VAL   A H    1 
ATOM   707  H  HA   . VAL   A 1 46  ? 62.805 19.001  22.619 1.00 55.40  ?  738  VAL   A HA   1 
ATOM   708  H  HB   . VAL   A 1 46  ? 62.478 18.666  25.605 1.00 63.43  ?  738  VAL   A HB   1 
ATOM   709  H  HG11 . VAL   A 1 46  ? 63.330 16.312  25.300 1.00 82.61  ?  738  VAL   A HG11 1 
ATOM   710  H  HG12 . VAL   A 1 46  ? 61.674 16.629  24.845 1.00 82.61  ?  738  VAL   A HG12 1 
ATOM   711  H  HG13 . VAL   A 1 46  ? 62.913 16.468  23.595 1.00 82.61  ?  738  VAL   A HG13 1 
ATOM   712  H  HG21 . VAL   A 1 46  ? 64.905 17.994  25.496 1.00 65.47  ?  738  VAL   A HG21 1 
ATOM   713  H  HG22 . VAL   A 1 46  ? 64.920 18.499  23.807 1.00 65.47  ?  738  VAL   A HG22 1 
ATOM   714  H  HG23 . VAL   A 1 46  ? 64.612 19.662  25.089 1.00 65.47  ?  738  VAL   A HG23 1 
ATOM   715  N  N    . LYS   A 1 47  ? 60.677 17.829  22.198 1.00 42.51  ?  739  LYS   A N    1 
ATOM   716  C  CA   . LYS   A 1 47  ? 59.426 17.145  21.902 1.00 42.10  ?  739  LYS   A CA   1 
ATOM   717  C  C    . LYS   A 1 47  ? 59.678 15.644  21.922 1.00 42.36  ?  739  LYS   A C    1 
ATOM   718  O  O    . LYS   A 1 47  ? 60.482 15.154  21.133 1.00 39.20  ?  739  LYS   A O    1 
ATOM   719  C  CB   . LYS   A 1 47  ? 58.927 17.570  20.528 1.00 43.42  ?  739  LYS   A CB   1 
ATOM   720  C  CG   . LYS   A 1 47  ? 58.115 18.850  20.496 1.00 57.26  ?  739  LYS   A CG   1 
ATOM   721  C  CD   . LYS   A 1 47  ? 57.822 19.299  19.067 1.00 73.87  ?  739  LYS   A CD   1 
ATOM   722  C  CE   . LYS   A 1 47  ? 56.597 20.193  18.951 1.00 72.37  ?  739  LYS   A CE   1 
ATOM   723  N  NZ   . LYS   A 1 47  ? 56.076 20.199  17.574 1.00 85.38  1  739  LYS   A NZ   1 
ATOM   724  H  H    . LYS   A 1 47  ? 61.491 17.590  21.638 1.00 44.51  ?  739  LYS   A H    1 
ATOM   725  H  HA   . LYS   A 1 47  ? 58.650 17.359  22.641 1.00 44.10  ?  739  LYS   A HA   1 
ATOM   726  H  HB2  . LYS   A 1 47  ? 59.775 17.668  19.849 1.00 45.42  ?  739  LYS   A HB2  1 
ATOM   727  H  HB3  . LYS   A 1 47  ? 58.307 16.777  20.105 1.00 45.42  ?  739  LYS   A HB3  1 
ATOM   728  H  HG2  . LYS   A 1 47  ? 57.178 18.645  21.010 1.00 59.26  ?  739  LYS   A HG2  1 
ATOM   729  H  HG3  . LYS   A 1 47  ? 58.617 19.647  21.048 1.00 59.26  ?  739  LYS   A HG3  1 
ATOM   730  H  HD2  . LYS   A 1 47  ? 58.694 19.800  18.646 1.00 75.87  ?  739  LYS   A HD2  1 
ATOM   731  H  HD3  . LYS   A 1 47  ? 57.670 18.415  18.447 1.00 75.87  ?  739  LYS   A HD3  1 
ATOM   732  H  HE2  . LYS   A 1 47  ? 55.795 19.829  19.592 1.00 74.37  ?  739  LYS   A HE2  1 
ATOM   733  H  HE3  . LYS   A 1 47  ? 56.822 21.209  19.275 1.00 74.37  ?  739  LYS   A HE3  1 
ATOM   734  H  HZ1  . LYS   A 1 47  ? 56.750 20.641  16.963 1.00 87.38  ?  739  LYS   A HZ1  1 
ATOM   735  H  HZ2  . LYS   A 1 47  ? 55.906 19.254  17.263 1.00 87.38  ?  739  LYS   A HZ2  1 
ATOM   736  H  HZ3  . LYS   A 1 47  ? 55.216 20.727  17.545 1.00 87.38  ?  739  LYS   A HZ3  1 
ATOM   737  N  N    . ILE   A 1 48  ? 59.007 14.905  22.795 1.00 34.04  ?  740  ILE   A N    1 
ATOM   738  C  CA   . ILE   A 1 48  ? 59.262 13.469  22.923 1.00 34.53  ?  740  ILE   A CA   1 
ATOM   739  C  C    . ILE   A 1 48  ? 58.019 12.732  22.457 1.00 38.96  ?  740  ILE   A C    1 
ATOM   740  O  O    . ILE   A 1 48  ? 56.948 12.946  23.033 1.00 41.95  ?  740  ILE   A O    1 
ATOM   741  C  CB   . ILE   A 1 48  ? 59.657 13.092  24.362 1.00 36.22  ?  740  ILE   A CB   1 
ATOM   742  C  CG1  . ILE   A 1 48  ? 60.975 13.753  24.754 1.00 35.57  ?  740  ILE   A CG1  1 
ATOM   743  C  CG2  . ILE   A 1 48  ? 59.793 11.582  24.581 1.00 34.90  ?  740  ILE   A CG2  1 
ATOM   744  C  CD1  . ILE   A 1 48  ? 61.055 14.065  26.233 1.00 51.81  ?  740  ILE   A CD1  1 
ATOM   745  H  H    . ILE   A 1 48  ? 58.369 15.343  23.462 1.00 36.04  ?  740  ILE   A H    1 
ATOM   746  H  HA   . ILE   A 1 48  ? 60.114 13.170  22.329 1.00 36.53  ?  740  ILE   A HA   1 
ATOM   747  H  HB   . ILE   A 1 48  ? 58.869 13.458  25.022 1.00 38.22  ?  740  ILE   A HB   1 
ATOM   748  H  HG12 . ILE   A 1 48  ? 61.823 13.136  24.452 1.00 37.57  ?  740  ILE   A HG12 1 
ATOM   749  H  HG13 . ILE   A 1 48  ? 61.109 14.678  24.205 1.00 37.57  ?  740  ILE   A HG13 1 
ATOM   750  H  HG21 . ILE   A 1 48  ? 60.153 11.355  25.584 1.00 36.90  ?  740  ILE   A HG21 1 
ATOM   751  H  HG22 . ILE   A 1 48  ? 58.848 11.054  24.463 1.00 36.90  ?  740  ILE   A HG22 1 
ATOM   752  H  HG23 . ILE   A 1 48  ? 60.500 11.146  23.873 1.00 36.90  ?  740  ILE   A HG23 1 
ATOM   753  H  HD11 . ILE   A 1 48  ? 61.941 14.656  26.454 1.00 53.81  ?  740  ILE   A HD11 1 
ATOM   754  H  HD12 . ILE   A 1 48  ? 60.195 14.644  26.566 1.00 53.81  ?  740  ILE   A HD12 1 
ATOM   755  H  HD13 . ILE   A 1 48  ? 61.106 13.157  26.831 1.00 53.81  ?  740  ILE   A HD13 1 
ATOM   756  N  N    . PRO   A 1 49  ? 58.095 11.875  21.429 1.00 39.49  ?  741  PRO   A N    1 
ATOM   757  C  CA   . PRO   A 1 49  ? 56.956 11.067  21.030 1.00 38.42  ?  741  PRO   A CA   1 
ATOM   758  C  C    . PRO   A 1 49  ? 56.702 9.963   22.037 1.00 40.61  ?  741  PRO   A C    1 
ATOM   759  O  O    . PRO   A 1 49  ? 57.617 9.228   22.438 1.00 36.58  ?  741  PRO   A O    1 
ATOM   760  C  CB   . PRO   A 1 49  ? 57.301 10.524  19.658 1.00 34.53  ?  741  PRO   A CB   1 
ATOM   761  C  CG   . PRO   A 1 49  ? 58.812 10.683  19.501 1.00 30.43  ?  741  PRO   A CG   1 
ATOM   762  C  CD   . PRO   A 1 49  ? 59.249 11.710  20.553 1.00 35.31  ?  741  PRO   A CD   1 
ATOM   763  H  HA   . PRO   A 1 49  ? 56.066 11.689  20.943 1.00 40.42  ?  741  PRO   A HA   1 
ATOM   764  H  HB2  . PRO   A 1 49  ? 56.980 9.494   19.502 1.00 36.53  ?  741  PRO   A HB2  1 
ATOM   765  H  HB3  . PRO   A 1 49  ? 56.797 11.128  18.902 1.00 36.53  ?  741  PRO   A HB3  1 
ATOM   766  H  HG2  . PRO   A 1 49  ? 59.300 9.728   19.702 1.00 32.43  ?  741  PRO   A HG2  1 
ATOM   767  H  HG3  . PRO   A 1 49  ? 59.096 10.982  18.491 1.00 32.43  ?  741  PRO   A HG3  1 
ATOM   768  H  HD2  . PRO   A 1 49  ? 60.110 11.329  21.103 1.00 37.31  ?  741  PRO   A HD2  1 
ATOM   769  H  HD3  . PRO   A 1 49  ? 59.513 12.663  20.097 1.00 37.31  ?  741  PRO   A HD3  1 
ATOM   770  N  N    . VAL   A 1 50  ? 55.439 9.870   22.421 1.00 38.12  ?  742  VAL   A N    1 
ATOM   771  C  CA   . VAL   A 1 50  ? 55.023 9.051   23.543 1.00 24.94  ?  742  VAL   A CA   1 
ATOM   772  C  C    . VAL   A 1 50  ? 53.827 8.204   23.164 1.00 33.61  ?  742  VAL   A C    1 
ATOM   773  O  O    . VAL   A 1 50  ? 53.067 8.540   22.250 1.00 37.09  ?  742  VAL   A O    1 
ATOM   774  C  CB   . VAL   A 1 50  ? 54.796 9.886   24.819 1.00 30.13  ?  742  VAL   A CB   1 
ATOM   775  C  CG1  . VAL   A 1 50  ? 56.091 10.429  25.390 1.00 22.80  ?  742  VAL   A CG1  1 
ATOM   776  C  CG2  . VAL   A 1 50  ? 53.797 11.022  24.642 1.00 25.42  ?  742  VAL   A CG2  1 
ATOM   777  H  H    . VAL   A 1 50  ? 54.725 10.439  21.973 1.00 40.12  ?  742  VAL   A H    1 
ATOM   778  H  HA   . VAL   A 1 50  ? 55.810 8.330   23.765 1.00 26.94  ?  742  VAL   A HA   1 
ATOM   779  H  HB   . VAL   A 1 50  ? 54.382 9.220   25.578 1.00 32.13  ?  742  VAL   A HB   1 
ATOM   780  H  HG11 . VAL   A 1 50  ? 55.943 10.850  26.384 1.00 24.80  ?  742  VAL   A HG11 1 
ATOM   781  H  HG12 . VAL   A 1 50  ? 56.837 9.640   25.458 1.00 24.80  ?  742  VAL   A HG12 1 
ATOM   782  H  HG13 . VAL   A 1 50  ? 56.507 11.213  24.765 1.00 24.80  ?  742  VAL   A HG13 1 
ATOM   783  H  HG21 . VAL   A 1 50  ? 53.566 11.498  25.595 1.00 27.42  ?  742  VAL   A HG21 1 
ATOM   784  H  HG22 . VAL   A 1 50  ? 54.191 11.790  23.979 1.00 27.42  ?  742  VAL   A HG22 1 
ATOM   785  H  HG23 . VAL   A 1 50  ? 52.855 10.672  24.220 1.00 27.42  ?  742  VAL   A HG23 1 
ATOM   786  N  N    . ALA   A 1 51  ? 53.670 7.118   23.906 1.00 33.18  ?  743  ALA   A N    1 
ATOM   787  C  CA   . ALA   A 1 51  ? 52.408 6.423   24.003 1.00 32.01  ?  743  ALA   A CA   1 
ATOM   788  C  C    . ALA   A 1 51  ? 51.807 6.766   25.364 1.00 44.32  ?  743  ALA   A C    1 
ATOM   789  O  O    . ALA   A 1 51  ? 52.470 6.637   26.398 1.00 37.80  ?  743  ALA   A O    1 
ATOM   790  C  CB   . ALA   A 1 51  ? 52.627 4.924   23.927 1.00 27.46  ?  743  ALA   A CB   1 
ATOM   791  H  H    . ALA   A 1 51  ? 54.336 6.976   24.666 1.00 35.18  ?  743  ALA   A H    1 
ATOM   792  H  HA   . ALA   A 1 51  ? 51.743 6.702   23.192 1.00 34.01  ?  743  ALA   A HA   1 
ATOM   793  H  HB1  . ALA   A 1 51  ? 51.701 4.374   24.100 1.00 29.46  ?  743  ALA   A HB1  1 
ATOM   794  H  HB2  . ALA   A 1 51  ? 52.989 4.641   22.939 1.00 29.46  ?  743  ALA   A HB2  1 
ATOM   795  H  HB3  . ALA   A 1 51  ? 53.362 4.579   24.655 1.00 29.46  ?  743  ALA   A HB3  1 
ATOM   796  N  N    . ILE   A 1 52  ? 50.563 7.222   25.354 1.00 45.22  ?  744  ILE   A N    1 
ATOM   797  C  CA   . ILE   A 1 52  ? 49.864 7.615   26.577 1.00 40.34  ?  744  ILE   A CA   1 
ATOM   798  C  C    . ILE   A 1 52  ? 48.786 6.563   26.822 1.00 50.68  ?  744  ILE   A C    1 
ATOM   799  O  O    . ILE   A 1 52  ? 47.837 6.468   26.042 1.00 44.25  ?  744  ILE   A O    1 
ATOM   800  C  CB   . ILE   A 1 52  ? 49.236 9.011   26.405 1.00 46.44  ?  744  ILE   A CB   1 
ATOM   801  C  CG1  . ILE   A 1 52  ? 50.268 10.092  26.065 1.00 35.40  ?  744  ILE   A CG1  1 
ATOM   802  C  CG2  . ILE   A 1 52  ? 48.394 9.448   27.608 1.00 47.47  ?  744  ILE   A CG2  1 
ATOM   803  C  CD1  . ILE   A 1 52  ? 49.692 11.205  25.205 1.00 59.07  ?  744  ILE   A CD1  1 
ATOM   804  H  H    . ILE   A 1 52  ? 50.072 7.286   24.465 1.00 47.22  ?  744  ILE   A H    1 
ATOM   805  H  HA   . ILE   A 1 52  ? 50.535 7.662   27.435 1.00 42.34  ?  744  ILE   A HA   1 
ATOM   806  H  HB   . ILE   A 1 52  ? 48.555 8.944   25.558 1.00 48.44  ?  744  ILE   A HB   1 
ATOM   807  H  HG12 . ILE   A 1 52  ? 50.685 10.521  26.971 1.00 37.40  ?  744  ILE   A HG12 1 
ATOM   808  H  HG13 . ILE   A 1 52  ? 51.121 9.678   25.528 1.00 37.40  ?  744  ILE   A HG13 1 
ATOM   809  H  HG21 . ILE   A 1 52  ? 48.021 10.465  27.491 1.00 49.47  ?  744  ILE   A HG21 1 
ATOM   810  H  HG22 . ILE   A 1 52  ? 47.518 8.816   27.755 1.00 49.47  ?  744  ILE   A HG22 1 
ATOM   811  H  HG23 . ILE   A 1 52  ? 48.967 9.422   28.532 1.00 49.47  ?  744  ILE   A HG23 1 
ATOM   812  H  HD11 . ILE   A 1 52  ? 50.444 11.966  24.994 1.00 61.07  ?  744  ILE   A HD11 1 
ATOM   813  H  HD12 . ILE   A 1 52  ? 49.334 10.816  24.251 1.00 61.07  ?  744  ILE   A HD12 1 
ATOM   814  H  HD13 . ILE   A 1 52  ? 48.854 11.699  25.695 1.00 61.07  ?  744  ILE   A HD13 1 
ATOM   815  N  N    . LYS   A 1 53  ? 48.941 5.765   27.872 1.00 40.83  ?  745  LYS   A N    1 
ATOM   816  C  CA   . LYS   A 1 53  ? 47.950 4.753   28.216 1.00 47.01  ?  745  LYS   A CA   1 
ATOM   817  C  C    . LYS   A 1 53  ? 47.069 5.319   29.320 1.00 60.26  ?  745  LYS   A C    1 
ATOM   818  O  O    . LYS   A 1 53  ? 47.502 5.490   30.461 1.00 59.29  ?  745  LYS   A O    1 
ATOM   819  C  CB   . LYS   A 1 53  ? 48.661 3.486   28.681 1.00 52.71  ?  745  LYS   A CB   1 
ATOM   820  C  CG   . LYS   A 1 53  ? 47.768 2.361   29.201 1.00 56.60  ?  745  LYS   A CG   1 
ATOM   821  C  CD   . LYS   A 1 53  ? 48.570 1.138   29.631 1.00 53.75  ?  745  LYS   A CD   1 
ATOM   822  C  CE   . LYS   A 1 53  ? 47.672 -0.028  30.025 1.00 68.25  ?  745  LYS   A CE   1 
ATOM   823  N  NZ   . LYS   A 1 53  ? 48.425 -1.274  30.240 1.00 69.14  1  745  LYS   A NZ   1 
ATOM   824  H  H    . LYS   A 1 53  ? 49.691 5.967   28.534 1.00 42.83  ?  745  LYS   A H    1 
ATOM   825  H  HA   . LYS   A 1 53  ? 47.338 4.473   27.361 1.00 49.01  ?  745  LYS   A HA   1 
ATOM   826  H  HB2  . LYS   A 1 53  ? 49.229 3.100   27.836 1.00 54.71  ?  745  LYS   A HB2  1 
ATOM   827  H  HB3  . LYS   A 1 53  ? 49.395 3.737   29.444 1.00 54.71  ?  745  LYS   A HB3  1 
ATOM   828  H  HG2  . LYS   A 1 53  ? 47.183 2.700   30.058 1.00 58.60  ?  745  LYS   A HG2  1 
ATOM   829  H  HG3  . LYS   A 1 53  ? 47.050 2.087   28.427 1.00 58.60  ?  745  LYS   A HG3  1 
ATOM   830  H  HD2  . LYS   A 1 53  ? 49.236 0.847   28.825 1.00 55.75  ?  745  LYS   A HD2  1 
ATOM   831  H  HD3  . LYS   A 1 53  ? 49.220 1.394   30.470 1.00 55.75  ?  745  LYS   A HD3  1 
ATOM   832  H  HE2  . LYS   A 1 53  ? 47.120 0.213   30.935 1.00 70.25  ?  745  LYS   A HE2  1 
ATOM   833  H  HE3  . LYS   A 1 53  ? 46.938 -0.219  29.244 1.00 70.25  ?  745  LYS   A HE3  1 
ATOM   834  H  HZ1  . LYS   A 1 53  ? 49.135 -1.163  30.958 1.00 71.14  ?  745  LYS   A HZ1  1 
ATOM   835  H  HZ2  . LYS   A 1 53  ? 47.788 -1.998  30.536 1.00 71.14  ?  745  LYS   A HZ2  1 
ATOM   836  H  HZ3  . LYS   A 1 53  ? 48.860 -1.559  29.375 1.00 71.14  ?  745  LYS   A HZ3  1 
ATOM   837  N  N    . GLU   A 1 54  ? 45.836 5.622   28.958 1.00 63.24  ?  746  GLU   A N    1 
ATOM   838  C  CA   . GLU   A 1 54  ? 44.849 6.144   29.892 1.00 75.44  ?  746  GLU   A CA   1 
ATOM   839  C  C    . GLU   A 1 54  ? 43.934 5.007   30.322 1.00 77.39  ?  746  GLU   A C    1 
ATOM   840  O  O    . GLU   A 1 54  ? 43.497 4.238   29.460 1.00 64.75  ?  746  GLU   A O    1 
ATOM   841  C  CB   . GLU   A 1 54  ? 44.036 7.193   29.135 1.00 73.77  ?  746  GLU   A CB   1 
ATOM   842  C  CG   . GLU   A 1 54  ? 42.917 7.887   29.905 1.00 66.50  ?  746  GLU   A CG   1 
ATOM   843  C  CD   . GLU   A 1 54  ? 42.269 8.926   29.023 1.00 72.18  ?  746  GLU   A CD   1 
ATOM   844  O  OE1  . GLU   A 1 54  ? 42.420 10.130  29.303 1.00 70.26  ?  746  GLU   A OE1  1 
ATOM   845  O  OE2  . GLU   A 1 54  ? 41.601 8.549   28.037 1.00 82.25  -1 746  GLU   A OE2  1 
ATOM   846  H  H    . GLU   A 1 54  ? 45.531 5.383   28.016 1.00 65.24  ?  746  GLU   A H    1 
ATOM   847  H  HA   . GLU   A 1 54  ? 45.310 6.610   30.762 1.00 77.44  ?  746  GLU   A HA   1 
ATOM   848  H  HB2  . GLU   A 1 54  ? 44.726 7.953   28.762 1.00 75.77  ?  746  GLU   A HB2  1 
ATOM   849  H  HB3  . GLU   A 1 54  ? 43.608 6.717   28.250 1.00 75.77  ?  746  GLU   A HB3  1 
ATOM   850  H  HG2  . GLU   A 1 54  ? 42.166 7.173   30.224 1.00 68.50  ?  746  GLU   A HG2  1 
ATOM   851  H  HG3  . GLU   A 1 54  ? 43.317 8.361   30.802 1.00 68.50  ?  746  GLU   A HG3  1 
ATOM   852  N  N    . LEU   A 1 55  ? 43.591 4.932   31.614 1.00 87.85  ?  747  LEU   A N    1 
ATOM   853  C  CA   . LEU   A 1 55  ? 42.682 3.868   32.107 1.00 100.44 ?  747  LEU   A CA   1 
ATOM   854  C  C    . LEU   A 1 55  ? 41.291 3.882   31.468 1.00 107.99 ?  747  LEU   A C    1 
ATOM   855  O  O    . LEU   A 1 55  ? 40.593 2.871   31.397 1.00 99.75  ?  747  LEU   A O    1 
ATOM   856  C  CB   . LEU   A 1 55  ? 42.465 3.871   33.631 1.00 101.29 ?  747  LEU   A CB   1 
ATOM   857  C  CG   . LEU   A 1 55  ? 43.510 4.519   34.525 1.00 112.24 ?  747  LEU   A CG   1 
ATOM   858  C  CD1  . LEU   A 1 55  ? 43.022 4.559   35.962 1.00 114.98 ?  747  LEU   A CD1  1 
ATOM   859  C  CD2  . LEU   A 1 55  ? 44.875 3.860   34.446 1.00 108.66 ?  747  LEU   A CD2  1 
ATOM   860  H  H    . LEU   A 1 55  ? 44.064 5.532   32.281 1.00 89.85  ?  747  LEU   A H    1 
ATOM   861  H  HA   . LEU   A 1 55  ? 43.149 2.916   31.844 1.00 102.44 ?  747  LEU   A HA   1 
ATOM   862  H  HB2  . LEU   A 1 55  ? 41.522 4.372   33.866 1.00 103.29 ?  747  LEU   A HB2  1 
ATOM   863  H  HB3  . LEU   A 1 55  ? 42.313 2.840   33.954 1.00 103.29 ?  747  LEU   A HB3  1 
ATOM   864  H  HG   . LEU   A 1 55  ? 43.601 5.553   34.214 1.00 114.24 ?  747  LEU   A HG   1 
ATOM   865  H  HD11 . LEU   A 1 55  ? 43.764 5.002   36.626 1.00 116.98 ?  747  LEU   A HD11 1 
ATOM   866  H  HD12 . LEU   A 1 55  ? 42.108 5.146   36.064 1.00 116.98 ?  747  LEU   A HD12 1 
ATOM   867  H  HD13 . LEU   A 1 55  ? 42.812 3.557   36.340 1.00 116.98 ?  747  LEU   A HD13 1 
ATOM   868  H  HD21 . LEU   A 1 55  ? 45.637 4.456   34.945 1.00 110.66 ?  747  LEU   A HD21 1 
ATOM   869  H  HD22 . LEU   A 1 55  ? 44.861 2.892   34.941 1.00 110.66 ?  747  LEU   A HD22 1 
ATOM   870  H  HD23 . LEU   A 1 55  ? 45.210 3.714   33.420 1.00 110.66 ?  747  LEU   A HD23 1 
ATOM   871  N  N    . ARG   A 1 56  ? 40.886 5.073   31.044 1.00 116.87 ?  748  ARG   A N    1 
ATOM   872  C  CA   . ARG   A 1 56  ? 39.715 5.310   30.209 1.00 123.35 ?  748  ARG   A CA   1 
ATOM   873  C  C    . ARG   A 1 56  ? 38.432 5.362   31.017 1.00 123.81 ?  748  ARG   A C    1 
ATOM   874  O  O    . ARG   A 1 56  ? 37.365 4.960   30.555 1.00 122.27 ?  748  ARG   A O    1 
ATOM   875  C  CB   . ARG   A 1 56  ? 39.672 4.460   28.938 1.00 125.29 ?  748  ARG   A CB   1 
ATOM   876  C  CG   . ARG   A 1 56  ? 38.830 4.987   27.781 1.00 119.71 ?  748  ARG   A CG   1 
ATOM   877  C  CD   . ARG   A 1 56  ? 39.380 6.263   27.164 1.00 117.73 ?  748  ARG   A CD   1 
ATOM   878  N  NE   . ARG   A 1 56  ? 38.938 6.401   25.769 1.00 116.36 ?  748  ARG   A NE   1 
ATOM   879  C  CZ   . ARG   A 1 56  ? 37.954 7.225   25.367 0.05 110.17 ?  748  ARG   A CZ   1 
ATOM   880  N  NH1  . ARG   A 1 56  ? 37.301 7.987   26.252 0.05 108.14 ?  748  ARG   A NH1  1 
ATOM   881  N  NH2  . ARG   A 1 56  ? 37.625 7.281   24.074 0.05 108.20 1  748  ARG   A NH2  1 
ATOM   882  H  H    . ARG   A 1 56  ? 41.469 5.861   31.292 1.00 118.87 ?  748  ARG   A H    1 
ATOM   883  H  HA   . ARG   A 1 56  ? 39.861 6.340   29.885 1.00 125.35 ?  748  ARG   A HA   1 
ATOM   884  H  HB2  . ARG   A 1 56  ? 40.687 4.300   28.574 1.00 127.29 ?  748  ARG   A HB2  1 
ATOM   885  H  HB3  . ARG   A 1 56  ? 39.275 3.481   29.206 1.00 127.29 ?  748  ARG   A HB3  1 
ATOM   886  H  HG2  . ARG   A 1 56  ? 38.780 4.207   27.020 1.00 121.71 ?  748  ARG   A HG2  1 
ATOM   887  H  HG3  . ARG   A 1 56  ? 37.798 5.148   28.090 1.00 121.71 ?  748  ARG   A HG3  1 
ATOM   888  H  HD2  . ARG   A 1 56  ? 39.145 7.137   27.769 1.00 119.73 ?  748  ARG   A HD2  1 
ATOM   889  H  HD3  . ARG   A 1 56  ? 40.467 6.208   27.134 1.00 119.73 ?  748  ARG   A HD3  1 
ATOM   890  H  HE   . ARG   A 1 56  ? 39.416 5.830   25.081 1.00 118.36 ?  748  ARG   A HE   1 
ATOM   891  H  HH11 . ARG   A 1 56  ? 37.545 7.949   27.230 0.05 110.14 ?  748  ARG   A HH11 1 
ATOM   892  H  HH12 . ARG   A 1 56  ? 36.562 8.603   25.946 0.05 110.14 ?  748  ARG   A HH12 1 
ATOM   893  H  HH21 . ARG   A 1 56  ? 38.114 6.709   23.401 0.05 110.20 ?  748  ARG   A HH21 1 
ATOM   894  H  HH22 . ARG   A 1 56  ? 36.887 7.896   23.764 0.05 110.20 ?  748  ARG   A HH22 1 
ATOM   895  N  N    . GLU   A 1 57  ? 38.573 5.801   32.263 1.00 123.23 ?  749  GLU   A N    1 
ATOM   896  C  CA   . GLU   A 1 57  ? 37.462 5.822   33.204 1.00 122.34 ?  749  GLU   A CA   1 
ATOM   897  C  C    . GLU   A 1 57  ? 37.191 4.457   33.832 1.00 123.55 ?  749  GLU   A C    1 
ATOM   898  O  O    . GLU   A 1 57  ? 36.138 4.221   34.434 1.00 123.90 ?  749  GLU   A O    1 
ATOM   899  C  CB   . GLU   A 1 57  ? 36.228 6.592   32.722 1.00 121.97 ?  749  GLU   A CB   1 
ATOM   900  C  CG   . GLU   A 1 57  ? 35.361 7.208   33.826 1.00 121.85 ?  749  GLU   A CG   1 
ATOM   901  C  CD   . GLU   A 1 57  ? 33.965 7.453   33.299 1.00 122.50 ?  749  GLU   A CD   1 
ATOM   902  O  OE1  . GLU   A 1 57  ? 33.826 8.042   32.207 1.00 121.43 ?  749  GLU   A OE1  1 
ATOM   903  O  OE2  . GLU   A 1 57  ? 32.991 7.057   33.971 1.00 123.46 -1 749  GLU   A OE2  1 
ATOM   904  H  H    . GLU   A 1 57  ? 39.496 6.084   32.574 1.00 125.23 ?  749  GLU   A H    1 
ATOM   905  H  HA   . GLU   A 1 57  ? 37.863 6.410   34.030 1.00 124.34 ?  749  GLU   A HA   1 
ATOM   906  H  HB2  . GLU   A 1 57  ? 36.539 7.398   32.056 1.00 123.97 ?  749  GLU   A HB2  1 
ATOM   907  H  HB3  . GLU   A 1 57  ? 35.622 5.920   32.110 1.00 123.97 ?  749  GLU   A HB3  1 
ATOM   908  H  HG2  . GLU   A 1 57  ? 35.307 6.552   34.693 1.00 123.85 ?  749  GLU   A HG2  1 
ATOM   909  H  HG3  . GLU   A 1 57  ? 35.789 8.149   34.175 1.00 123.85 ?  749  GLU   A HG3  1 
ATOM   910  N  N    . ALA   A 1 58  ? 38.176 3.559   33.750 1.00 123.12 ?  750  ALA   A N    1 
ATOM   911  C  CA   . ALA   A 1 58  ? 38.152 2.283   34.460 1.00 120.88 ?  750  ALA   A CA   1 
ATOM   912  C  C    . ALA   A 1 58  ? 38.384 2.468   35.960 1.00 118.23 ?  750  ALA   A C    1 
ATOM   913  O  O    . ALA   A 1 58  ? 39.324 1.959   36.572 1.00 114.60 ?  750  ALA   A O    1 
ATOM   914  C  CB   . ALA   A 1 58  ? 39.178 1.328   33.868 1.00 116.24 ?  750  ALA   A CB   1 
ATOM   915  H  H    . ALA   A 1 58  ? 38.977 3.768   33.170 1.00 125.12 ?  750  ALA   A H    1 
ATOM   916  H  HA   . ALA   A 1 58  ? 37.169 1.824   34.329 1.00 122.88 ?  750  ALA   A HA   1 
ATOM   917  H  HB1  . ALA   A 1 58  ? 39.138 0.354   34.357 1.00 118.24 ?  750  ALA   A HB1  1 
ATOM   918  H  HB2  . ALA   A 1 58  ? 38.988 1.158   32.808 1.00 118.24 ?  750  ALA   A HB2  1 
ATOM   919  H  HB3  . ALA   A 1 58  ? 40.196 1.705   33.967 1.00 118.24 ?  750  ALA   A HB3  1 
ATOM   920  N  N    . THR   A 1 59  ? 37.460 3.204   36.555 1.00 117.56 ?  751  THR   A N    1 
ATOM   921  C  CA   . THR   A 1 59  ? 37.376 3.579   37.962 1.00 115.98 ?  751  THR   A CA   1 
ATOM   922  C  C    . THR   A 1 59  ? 36.992 2.422   38.892 1.00 111.81 ?  751  THR   A C    1 
ATOM   923  O  O    . THR   A 1 59  ? 36.363 2.590   39.938 1.00 113.29 ?  751  THR   A O    1 
ATOM   924  C  CB   . THR   A 1 59  ? 36.447 4.806   38.109 1.00 116.47 ?  751  THR   A CB   1 
ATOM   925  O  OG1  . THR   A 1 59  ? 35.141 4.616   37.566 1.00 121.47 ?  751  THR   A OG1  1 
ATOM   926  C  CG2  . THR   A 1 59  ? 37.022 6.069   37.489 1.00 111.84 ?  751  THR   A CG2  1 
ATOM   927  H  H    . THR   A 1 59  ? 36.739 3.568   35.938 1.00 119.56 ?  751  THR   A H    1 
ATOM   928  H  HA   . THR   A 1 59  ? 38.371 3.885   38.289 1.00 117.98 ?  751  THR   A HA   1 
ATOM   929  H  HB   . THR   A 1 59  ? 36.314 5.014   39.174 1.00 118.47 ?  751  THR   A HB   1 
ATOM   930  H  HG1  . THR   A 1 59  ? 35.193 4.580   36.618 1.00 123.47 ?  751  THR   A HG1  1 
ATOM   931  H  HG21 . THR   A 1 59  ? 36.362 6.920   37.659 1.00 113.84 ?  751  THR   A HG21 1 
ATOM   932  H  HG22 . THR   A 1 59  ? 37.988 6.318   37.931 1.00 113.84 ?  751  THR   A HG22 1 
ATOM   933  H  HG23 . THR   A 1 59  ? 37.165 5.974   36.414 1.00 113.84 ?  751  THR   A HG23 1 
ATOM   934  N  N    . SER   A 1 60  ? 37.453 1.229   38.538 1.00 106.49 ?  752  SER   A N    1 
ATOM   935  C  CA   . SER   A 1 60  ? 37.607 0.188   39.514 1.00 105.96 ?  752  SER   A CA   1 
ATOM   936  C  C    . SER   A 1 60  ? 38.849 0.515   40.344 1.00 109.14 ?  752  SER   A C    1 
ATOM   937  O  O    . SER   A 1 60  ? 39.911 0.777   39.759 1.00 109.89 ?  752  SER   A O    1 
ATOM   938  C  CB   . SER   A 1 60  ? 37.826 -1.121  38.773 1.00 101.84 ?  752  SER   A CB   1 
ATOM   939  O  OG   . SER   A 1 60  ? 38.136 -2.178  39.655 1.00 103.34 ?  752  SER   A OG   1 
ATOM   940  H  H    . SER   A 1 60  ? 38.091 1.229   37.747 1.00 108.49 ?  752  SER   A H    1 
ATOM   941  H  HA   . SER   A 1 60  ? 36.693 0.104   40.102 1.00 107.96 ?  752  SER   A HA   1 
ATOM   942  H  HB2  . SER   A 1 60  ? 36.939 -1.389  38.197 1.00 103.84 ?  752  SER   A HB2  1 
ATOM   943  H  HB3  . SER   A 1 60  ? 38.638 -1.024  38.053 1.00 103.84 ?  752  SER   A HB3  1 
ATOM   944  H  HG   . SER   A 1 60  ? 37.329 -2.464  40.068 1.00 105.34 ?  752  SER   A HG   1 
ATOM   945  N  N    . PRO   A 1 61  ? 38.779 0.450   41.682 1.00 110.76 ?  753  PRO   A N    1 
ATOM   946  C  CA   . PRO   A 1 61  ? 39.967 0.594   42.512 1.00 107.12 ?  753  PRO   A CA   1 
ATOM   947  C  C    . PRO   A 1 61  ? 40.967 -0.553  42.366 1.00 100.97 ?  753  PRO   A C    1 
ATOM   948  O  O    . PRO   A 1 61  ? 42.166 -0.380  42.597 1.00 94.14  ?  753  PRO   A O    1 
ATOM   949  C  CB   . PRO   A 1 61  ? 39.424 0.745   43.922 1.00 109.29 ?  753  PRO   A CB   1 
ATOM   950  C  CG   . PRO   A 1 61  ? 38.040 0.095   43.907 1.00 108.39 ?  753  PRO   A CG   1 
ATOM   951  C  CD   . PRO   A 1 61  ? 37.562 0.203   42.456 1.00 107.86 ?  753  PRO   A CD   1 
ATOM   952  H  HA   . PRO   A 1 61  ? 40.487 1.516   42.246 1.00 109.12 ?  753  PRO   A HA   1 
ATOM   953  H  HB2  . PRO   A 1 61  ? 40.076 0.331   44.694 1.00 111.29 ?  753  PRO   A HB2  1 
ATOM   954  H  HB3  . PRO   A 1 61  ? 39.301 1.805   44.140 1.00 111.29 ?  753  PRO   A HB3  1 
ATOM   955  H  HG2  . PRO   A 1 61  ? 38.130 -0.956  44.184 1.00 110.39 ?  753  PRO   A HG2  1 
ATOM   956  H  HG3  . PRO   A 1 61  ? 37.350 0.562   44.612 1.00 110.39 ?  753  PRO   A HG3  1 
ATOM   957  H  HD2  . PRO   A 1 61  ? 37.048 -0.712  42.155 1.00 109.86 ?  753  PRO   A HD2  1 
ATOM   958  H  HD3  . PRO   A 1 61  ? 36.876 1.045   42.337 1.00 109.86 ?  753  PRO   A HD3  1 
ATOM   959  N  N    . LYS   A 1 62  ? 40.481 -1.705  41.904 1.00 94.17  ?  754  LYS   A N    1 
ATOM   960  C  CA   . LYS   A 1 62  ? 41.349 -2.830  41.593 1.00 95.46  ?  754  LYS   A CA   1 
ATOM   961  C  C    . LYS   A 1 62  ? 42.130 -2.598  40.303 1.00 96.84  ?  754  LYS   A C    1 
ATOM   962  O  O    . LYS   A 1 62  ? 43.338 -2.833  40.265 1.00 94.58  ?  754  LYS   A O    1 
ATOM   963  C  CB   . LYS   A 1 62  ? 40.522 -4.106  41.478 1.00 94.83  ?  754  LYS   A CB   1 
ATOM   964  C  CG   . LYS   A 1 62  ? 39.803 -4.468  42.778 1.00 99.23  ?  754  LYS   A CG   1 
ATOM   965  C  CD   . LYS   A 1 62  ? 38.895 -5.682  42.647 1.00 99.60  ?  754  LYS   A CD   1 
ATOM   966  C  CE   . LYS   A 1 62  ? 38.301 -6.109  43.983 1.00 102.20 ?  754  LYS   A CE   1 
ATOM   967  N  NZ   . LYS   A 1 62  ? 37.376 -7.244  43.827 1.00 109.95 1  754  LYS   A NZ   1 
ATOM   968  H  H    . LYS   A 1 62  ? 39.503 -1.779  41.666 1.00 96.17  ?  754  LYS   A H    1 
ATOM   969  H  HA   . LYS   A 1 62  ? 42.073 -2.964  42.401 1.00 97.46  ?  754  LYS   A HA   1 
ATOM   970  H  HB2  . LYS   A 1 62  ? 39.797 -4.013  40.668 1.00 96.83  ?  754  LYS   A HB2  1 
ATOM   971  H  HB3  . LYS   A 1 62  ? 41.175 -4.934  41.193 1.00 96.83  ?  754  LYS   A HB3  1 
ATOM   972  H  HG2  . LYS   A 1 62  ? 40.547 -4.647  43.555 1.00 101.23 ?  754  LYS   A HG2  1 
ATOM   973  H  HG3  . LYS   A 1 62  ? 39.200 -3.627  43.124 1.00 101.23 ?  754  LYS   A HG3  1 
ATOM   974  H  HD2  . LYS   A 1 62  ? 38.091 -5.456  41.944 1.00 101.60 ?  754  LYS   A HD2  1 
ATOM   975  H  HD3  . LYS   A 1 62  ? 39.454 -6.515  42.218 1.00 101.60 ?  754  LYS   A HD3  1 
ATOM   976  H  HE2  . LYS   A 1 62  ? 39.094 -6.401  44.672 1.00 104.20 ?  754  LYS   A HE2  1 
ATOM   977  H  HE3  . LYS   A 1 62  ? 37.761 -5.283  44.446 1.00 104.20 ?  754  LYS   A HE3  1 
ATOM   978  H  HZ1  . LYS   A 1 62  ? 37.037 -7.528  44.734 1.00 111.95 ?  754  LYS   A HZ1  1 
ATOM   979  H  HZ2  . LYS   A 1 62  ? 36.594 -6.969  43.252 1.00 111.95 ?  754  LYS   A HZ2  1 
ATOM   980  H  HZ3  . LYS   A 1 62  ? 37.855 -8.018  43.394 1.00 111.95 ?  754  LYS   A HZ3  1 
ATOM   981  N  N    . ALA   A 1 63  ? 41.468 -2.055  39.277 1.00 96.06  ?  755  ALA   A N    1 
ATOM   982  C  CA   . ALA   A 1 63  ? 42.174 -1.728  38.030 1.00 98.43  ?  755  ALA   A CA   1 
ATOM   983  C  C    . ALA   A 1 63  ? 43.172 -0.585  38.177 1.00 99.10  ?  755  ALA   A C    1 
ATOM   984  O  O    . ALA   A 1 63  ? 44.248 -0.597  37.575 1.00 99.35  ?  755  ALA   A O    1 
ATOM   985  C  CB   . ALA   A 1 63  ? 41.198 -1.357  36.928 1.00 94.02  ?  755  ALA   A CB   1 
ATOM   986  H  H    . ALA   A 1 63  ? 40.473 -1.891  39.357 1.00 98.06  ?  755  ALA   A H    1 
ATOM   987  H  HA   . ALA   A 1 63  ? 42.726 -2.613  37.705 1.00 100.43 ?  755  ALA   A HA   1 
ATOM   988  H  HB1  . ALA   A 1 63  ? 41.721 -1.210  35.981 1.00 96.02  ?  755  ALA   A HB1  1 
ATOM   989  H  HB2  . ALA   A 1 63  ? 40.463 -2.145  36.770 1.00 96.02  ?  755  ALA   A HB2  1 
ATOM   990  H  HB3  . ALA   A 1 63  ? 40.668 -0.429  37.148 1.00 96.02  ?  755  ALA   A HB3  1 
ATOM   991  N  N    . ASN   A 1 64  ? 42.822 0.375   39.031 1.00 95.51  ?  756  ASN   A N    1 
ATOM   992  C  CA   . ASN   A 1 64  ? 43.750 1.438   39.417 1.00 89.54  ?  756  ASN   A CA   1 
ATOM   993  C  C    . ASN   A 1 64  ? 44.985 0.919   40.146 1.00 85.21  ?  756  ASN   A C    1 
ATOM   994  O  O    . ASN   A 1 64  ? 46.104 1.350   39.863 1.00 84.20  ?  756  ASN   A O    1 
ATOM   995  C  CB   . ASN   A 1 64  ? 43.047 2.516   40.248 1.00 90.42  ?  756  ASN   A CB   1 
ATOM   996  C  CG   . ASN   A 1 64  ? 42.302 3.522   39.398 1.00 97.78  ?  756  ASN   A CG   1 
ATOM   997  O  OD1  . ASN   A 1 64  ? 42.804 4.596   39.087 1.00 104.50 ?  756  ASN   A OD1  1 
ATOM   998  N  ND2  . ASN   A 1 64  ? 41.096 3.186   39.008 1.00 94.12  ?  756  ASN   A ND2  1 
ATOM   999  H  H    . ASN   A 1 64  ? 41.909 0.323   39.464 1.00 97.51  ?  756  ASN   A H    1 
ATOM   1000 H  HA   . ASN   A 1 64  ? 44.124 1.905   38.501 1.00 91.54  ?  756  ASN   A HA   1 
ATOM   1001 H  HB2  . ASN   A 1 64  ? 42.379 2.077   40.988 1.00 92.42  ?  756  ASN   A HB2  1 
ATOM   1002 H  HB3  . ASN   A 1 64  ? 43.779 3.084   40.823 1.00 92.42  ?  756  ASN   A HB3  1 
ATOM   1003 H  HD21 . ASN   A 1 64  ? 40.701 2.288   39.279 1.00 96.12  ?  756  ASN   A HD21 1 
ATOM   1004 H  HD22 . ASN   A 1 64  ? 40.567 3.818   38.433 1.00 96.12  ?  756  ASN   A HD22 1 
ATOM   1005 N  N    . LYS   A 1 65  ? 44.791 -0.056  41.036 1.00 78.58  ?  757  LYS   A N    1 
ATOM   1006 C  CA   . LYS   A 1 65  ? 45.919 -0.721  41.684 1.00 82.66  ?  757  LYS   A CA   1 
ATOM   1007 C  C    . LYS   A 1 65  ? 46.809 -1.488  40.711 1.00 83.87  ?  757  LYS   A C    1 
ATOM   1008 O  O    . LYS   A 1 65  ? 48.030 -1.358  40.758 1.00 90.42  ?  757  LYS   A O    1 
ATOM   1009 C  CB   . LYS   A 1 65  ? 45.442 -1.618  42.829 1.00 81.64  ?  757  LYS   A CB   1 
ATOM   1010 C  CG   . LYS   A 1 65  ? 46.567 -2.313  43.603 1.00 81.99  ?  757  LYS   A CG   1 
ATOM   1011 C  CD   . LYS   A 1 65  ? 46.210 -2.616  45.052 1.00 94.68  ?  757  LYS   A CD   1 
ATOM   1012 C  CE   . LYS   A 1 65  ? 47.333 -3.325  45.803 1.00 104.85 ?  757  LYS   A CE   1 
ATOM   1013 N  NZ   . LYS   A 1 65  ? 47.053 -3.405  47.248 1.00 108.61 1  757  LYS   A NZ   1 
ATOM   1014 H  H    . LYS   A 1 65  ? 43.850 -0.361  41.255 1.00 80.58  ?  757  LYS   A H    1 
ATOM   1015 H  HA   . LYS   A 1 65  ? 46.540 0.063   42.125 1.00 84.66  ?  757  LYS   A HA   1 
ATOM   1016 H  HB2  . LYS   A 1 65  ? 44.870 -0.994  43.517 1.00 83.64  ?  757  LYS   A HB2  1 
ATOM   1017 H  HB3  . LYS   A 1 65  ? 44.740 -2.368  42.463 1.00 83.64  ?  757  LYS   A HB3  1 
ATOM   1018 H  HG2  . LYS   A 1 65  ? 46.856 -3.230  43.085 1.00 83.99  ?  757  LYS   A HG2  1 
ATOM   1019 H  HG3  . LYS   A 1 65  ? 47.456 -1.680  43.600 1.00 83.99  ?  757  LYS   A HG3  1 
ATOM   1020 H  HD2  . LYS   A 1 65  ? 45.974 -1.680  45.562 1.00 96.68  ?  757  LYS   A HD2  1 
ATOM   1021 H  HD3  . LYS   A 1 65  ? 45.306 -3.226  45.091 1.00 96.68  ?  757  LYS   A HD3  1 
ATOM   1022 H  HE2  . LYS   A 1 65  ? 47.467 -4.333  45.410 1.00 106.85 ?  757  LYS   A HE2  1 
ATOM   1023 H  HE3  . LYS   A 1 65  ? 48.282 -2.803  45.671 1.00 106.85 ?  757  LYS   A HE3  1 
ATOM   1024 H  HZ1  . LYS   A 1 65  ? 47.207 -2.499  47.675 1.00 110.61 ?  757  LYS   A HZ1  1 
ATOM   1025 H  HZ2  . LYS   A 1 65  ? 46.094 -3.683  47.396 1.00 110.61 ?  757  LYS   A HZ2  1 
ATOM   1026 H  HZ3  . LYS   A 1 65  ? 47.668 -4.078  47.678 1.00 110.61 ?  757  LYS   A HZ3  1 
ATOM   1027 N  N    . GLU   A 1 66  ? 46.191 -2.233  39.804 1.00 85.45  ?  758  GLU   A N    1 
ATOM   1028 C  CA   . GLU   A 1 66  ? 46.932 -3.016  38.819 1.00 81.62  ?  758  GLU   A CA   1 
ATOM   1029 C  C    . GLU   A 1 66  ? 47.778 -2.182  37.864 1.00 78.37  ?  758  GLU   A C    1 
ATOM   1030 O  O    . GLU   A 1 66  ? 48.930 -2.519  37.572 1.00 69.11  ?  758  GLU   A O    1 
ATOM   1031 C  CB   . GLU   A 1 66  ? 45.956 -3.866  38.015 1.00 86.56  ?  758  GLU   A CB   1 
ATOM   1032 C  CG   . GLU   A 1 66  ? 45.380 -5.036  38.826 1.00 92.29  ?  758  GLU   A CG   1 
ATOM   1033 C  CD   . GLU   A 1 66  ? 44.161 -5.618  38.130 1.00 100.87 ?  758  GLU   A CD   1 
ATOM   1034 O  OE1  . GLU   A 1 66  ? 43.958 -5.350  36.926 1.00 101.46 ?  758  GLU   A OE1  1 
ATOM   1035 O  OE2  . GLU   A 1 66  ? 43.394 -6.354  38.784 1.00 107.34 -1 758  GLU   A OE2  1 
ATOM   1036 H  H    . GLU   A 1 66  ? 45.180 -2.324  39.839 1.00 87.45  ?  758  GLU   A H    1 
ATOM   1037 H  HA   . GLU   A 1 66  ? 47.618 -3.679  39.353 1.00 83.62  ?  758  GLU   A HA   1 
ATOM   1038 H  HB2  . GLU   A 1 66  ? 45.160 -3.220  37.637 1.00 88.56  ?  758  GLU   A HB2  1 
ATOM   1039 H  HB3  . GLU   A 1 66  ? 46.453 -4.275  37.132 1.00 88.56  ?  758  GLU   A HB3  1 
ATOM   1040 H  HG2  . GLU   A 1 66  ? 46.129 -5.816  38.961 1.00 94.29  ?  758  GLU   A HG2  1 
ATOM   1041 H  HG3  . GLU   A 1 66  ? 45.079 -4.713  39.822 1.00 94.29  ?  758  GLU   A HG3  1 
ATOM   1042 N  N    . ILE   A 1 67  ? 47.215 -1.072  37.399 1.00 72.06  ?  759  ILE   A N    1 
ATOM   1043 C  CA   . ILE   A 1 67  ? 47.958 -0.217  36.480 1.00 74.26  ?  759  ILE   A CA   1 
ATOM   1044 C  C    . ILE   A 1 67  ? 49.063 0.565   37.207 1.00 68.51  ?  759  ILE   A C    1 
ATOM   1045 O  O    . ILE   A 1 67  ? 50.125 0.826   36.633 1.00 56.54  ?  759  ILE   A O    1 
ATOM   1046 C  CB   . ILE   A 1 67  ? 46.980 0.632   35.634 1.00 85.49  ?  759  ILE   A CB   1 
ATOM   1047 C  CG1  . ILE   A 1 67  ? 46.107 -0.306  34.773 1.00 100.19 ?  759  ILE   A CG1  1 
ATOM   1048 C  CG2  . ILE   A 1 67  ? 47.690 1.638   34.729 1.00 88.74  ?  759  ILE   A CG2  1 
ATOM   1049 C  CD1  . ILE   A 1 67  ? 44.878 0.308   34.114 1.00 109.45 ?  759  ILE   A CD1  1 
ATOM   1050 H  H    . ILE   A 1 67  ? 46.254 -0.844  37.636 1.00 74.06  ?  759  ILE   A H    1 
ATOM   1051 H  HA   . ILE   A 1 67  ? 48.484 -0.853  35.764 1.00 76.26  ?  759  ILE   A HA   1 
ATOM   1052 H  HB   . ILE   A 1 67  ? 46.330 1.187   36.314 1.00 87.49  ?  759  ILE   A HB   1 
ATOM   1053 H  HG12 . ILE   A 1 67  ? 46.727 -0.769  34.003 1.00 102.19 ?  759  ILE   A HG12 1 
ATOM   1054 H  HG13 . ILE   A 1 67  ? 45.735 -1.138  35.370 1.00 102.19 ?  759  ILE   A HG13 1 
ATOM   1055 H  HG21 . ILE   A 1 67  ? 47.005 2.162   34.067 1.00 90.74  ?  759  ILE   A HG21 1 
ATOM   1056 H  HG22 . ILE   A 1 67  ? 48.214 2.405   35.299 1.00 90.74  ?  759  ILE   A HG22 1 
ATOM   1057 H  HG23 . ILE   A 1 67  ? 48.422 1.138   34.093 1.00 90.74  ?  759  ILE   A HG23 1 
ATOM   1058 H  HD11 . ILE   A 1 67  ? 44.323 -0.451  33.560 1.00 111.45 ?  759  ILE   A HD11 1 
ATOM   1059 H  HD12 . ILE   A 1 67  ? 44.196 0.720   34.858 1.00 111.45 ?  759  ILE   A HD12 1 
ATOM   1060 H  HD13 . ILE   A 1 67  ? 45.133 1.090   33.400 1.00 111.45 ?  759  ILE   A HD13 1 
ATOM   1061 N  N    . LEU   A 1 68  ? 48.880 0.840   38.500 1.00 53.20  ?  760  LEU   A N    1 
ATOM   1062 C  CA   . LEU   A 1 68  ? 49.994 1.382   39.278 1.00 53.15  ?  760  LEU   A CA   1 
ATOM   1063 C  C    . LEU   A 1 68  ? 51.067 0.343   39.629 1.00 45.14  ?  760  LEU   A C    1 
ATOM   1064 O  O    . LEU   A 1 68  ? 52.244 0.693   39.742 1.00 46.76  ?  760  LEU   A O    1 
ATOM   1065 C  CB   . LEU   A 1 68  ? 49.493 2.071   40.539 1.00 51.50  ?  760  LEU   A CB   1 
ATOM   1066 C  CG   . LEU   A 1 68  ? 48.692 3.352   40.275 1.00 50.14  ?  760  LEU   A CG   1 
ATOM   1067 C  CD1  . LEU   A 1 68  ? 47.872 3.734   41.493 1.00 45.89  ?  760  LEU   A CD1  1 
ATOM   1068 C  CD2  . LEU   A 1 68  ? 49.573 4.524   39.866 1.00 44.48  ?  760  LEU   A CD2  1 
ATOM   1069 H  H    . LEU   A 1 68  ? 48.002 0.625   38.958 1.00 55.20  ?  760  LEU   A H    1 
ATOM   1070 H  HA   . LEU   A 1 68  ? 50.504 2.142   38.685 1.00 55.15  ?  760  LEU   A HA   1 
ATOM   1071 H  HB2  . LEU   A 1 68  ? 48.878 1.359   41.093 1.00 53.50  ?  760  LEU   A HB2  1 
ATOM   1072 H  HB3  . LEU   A 1 68  ? 50.332 2.310   41.196 1.00 53.50  ?  760  LEU   A HB3  1 
ATOM   1073 H  HG   . LEU   A 1 68  ? 47.985 3.169   39.465 1.00 52.14  ?  760  LEU   A HG   1 
ATOM   1074 H  HD11 . LEU   A 1 68  ? 47.270 4.622   41.304 1.00 47.89  ?  760  LEU   A HD11 1 
ATOM   1075 H  HD12 . LEU   A 1 68  ? 47.191 2.935   41.788 1.00 47.89  ?  760  LEU   A HD12 1 
ATOM   1076 H  HD13 . LEU   A 1 68  ? 48.523 3.953   42.338 1.00 47.89  ?  760  LEU   A HD13 1 
ATOM   1077 H  HD21 . LEU   A 1 68  ? 48.975 5.422   39.703 1.00 46.48  ?  760  LEU   A HD21 1 
ATOM   1078 H  HD22 . LEU   A 1 68  ? 50.308 4.761   40.636 1.00 46.48  ?  760  LEU   A HD22 1 
ATOM   1079 H  HD23 . LEU   A 1 68  ? 50.112 4.333   38.939 1.00 46.48  ?  760  LEU   A HD23 1 
ATOM   1080 N  N    . ASP   A 1 69  ? 50.700 -0.935  39.726 1.00 37.37  ?  761  ASP   A N    1 
ATOM   1081 C  CA   . ASP   A 1 69  ? 51.702 -2.009  39.817 1.00 42.60  ?  761  ASP   A CA   1 
ATOM   1082 C  C    . ASP   A 1 69  ? 52.540 -2.134  38.550 1.00 49.07  ?  761  ASP   A C    1 
ATOM   1083 O  O    . ASP   A 1 69  ? 53.768 -2.232  38.614 1.00 45.67  ?  761  ASP   A O    1 
ATOM   1084 C  CB   . ASP   A 1 69  ? 51.096 -3.384  40.128 1.00 46.79  ?  761  ASP   A CB   1 
ATOM   1085 C  CG   . ASP   A 1 69  ? 50.460 -3.512  41.501 1.00 62.46  ?  761  ASP   A CG   1 
ATOM   1086 O  OD1  . ASP   A 1 69  ? 50.886 -2.804  42.439 1.00 69.54  ?  761  ASP   A OD1  1 
ATOM   1087 O  OD2  . ASP   A 1 69  ? 49.529 -4.330  41.657 1.00 71.04  -1 761  ASP   A OD2  1 
ATOM   1088 H  H    . ASP   A 1 69  ? 49.714 -1.177  39.728 1.00 39.37  ?  761  ASP   A H    1 
ATOM   1089 H  HA   . ASP   A 1 69  ? 52.396 -1.755  40.622 1.00 44.60  ?  761  ASP   A HA   1 
ATOM   1090 H  HB2  . ASP   A 1 69  ? 50.352 -3.652  39.378 1.00 48.79  ?  761  ASP   A HB2  1 
ATOM   1091 H  HB3  . ASP   A 1 69  ? 51.867 -4.153  40.070 1.00 48.79  ?  761  ASP   A HB3  1 
ATOM   1092 N  N    . GLU   A 1 70  ? 51.880 -2.057  37.395 1.00 49.80  ?  762  GLU   A N    1 
ATOM   1093 C  CA   . GLU   A 1 70  ? 52.589 -1.939  36.124 1.00 51.28  ?  762  GLU   A CA   1 
ATOM   1094 C  C    . GLU   A 1 70  ? 53.554 -0.760  36.079 1.00 49.25  ?  762  GLU   A C    1 
ATOM   1095 O  O    . GLU   A 1 70  ? 54.727 -0.902  35.715 1.00 61.11  ?  762  GLU   A O    1 
ATOM   1096 C  CB   . GLU   A 1 70  ? 51.600 -1.956  34.954 1.00 61.92  ?  762  GLU   A CB   1 
ATOM   1097 C  CG   . GLU   A 1 70  ? 52.131 -1.491  33.592 1.00 79.19  ?  762  GLU   A CG   1 
ATOM   1098 C  CD   . GLU   A 1 70  ? 51.088 -1.738  32.528 1.00 87.11  ?  762  GLU   A CD   1 
ATOM   1099 O  OE1  . GLU   A 1 70  ? 50.013 -1.099  32.576 1.00 84.32  ?  762  GLU   A OE1  1 
ATOM   1100 O  OE2  . GLU   A 1 70  ? 51.329 -2.569  31.629 1.00 93.07  -1 762  GLU   A OE2  1 
ATOM   1101 H  H    . GLU   A 1 70  ? 50.865 -2.019  37.415 1.00 51.80  ?  762  GLU   A H    1 
ATOM   1102 H  HA   . GLU   A 1 70  ? 53.210 -2.833  36.022 1.00 53.28  ?  762  GLU   A HA   1 
ATOM   1103 H  HB2  . GLU   A 1 70  ? 51.194 -2.966  34.865 1.00 63.92  ?  762  GLU   A HB2  1 
ATOM   1104 H  HB3  . GLU   A 1 70  ? 50.750 -1.323  35.208 1.00 63.92  ?  762  GLU   A HB3  1 
ATOM   1105 H  HG2  . GLU   A 1 70  ? 52.374 -0.427  33.613 1.00 81.19  ?  762  GLU   A HG2  1 
ATOM   1106 H  HG3  . GLU   A 1 70  ? 53.049 -2.021  33.332 1.00 81.19  ?  762  GLU   A HG3  1 
ATOM   1107 N  N    . ALA   A 1 71  ? 53.053 0.393   36.515 1.00 47.02  ?  763  ALA   A N    1 
ATOM   1108 C  CA   . ALA   A 1 71  ? 53.853 1.609   36.545 1.00 37.54  ?  763  ALA   A CA   1 
ATOM   1109 C  C    . ALA   A 1 71  ? 55.065 1.521   37.458 1.00 35.99  ?  763  ALA   A C    1 
ATOM   1110 O  O    . ALA   A 1 71  ? 56.143 1.997   37.105 1.00 38.60  ?  763  ALA   A O    1 
ATOM   1111 C  CB   . ALA   A 1 71  ? 52.990 2.792   36.943 1.00 38.82  ?  763  ALA   A CB   1 
ATOM   1112 H  H    . ALA   A 1 71  ? 52.065 0.442   36.746 1.00 49.02  ?  763  ALA   A H    1 
ATOM   1113 H  HA   . ALA   A 1 71  ? 54.215 1.788   35.529 1.00 39.54  ?  763  ALA   A HA   1 
ATOM   1114 H  HB1  . ALA   A 1 71  ? 53.528 3.733   36.827 1.00 40.82  ?  763  ALA   A HB1  1 
ATOM   1115 H  HB2  . ALA   A 1 71  ? 52.094 2.850   36.327 1.00 40.82  ?  763  ALA   A HB2  1 
ATOM   1116 H  HB3  . ALA   A 1 71  ? 52.673 2.730   37.984 1.00 40.82  ?  763  ALA   A HB3  1 
ATOM   1117 N  N    . TYR   A 1 72  ? 54.895 0.859   38.603 1.00 34.69  ?  764  TYR   A N    1 
ATOM   1118 C  CA   . TYR   A 1 72  ? 55.999 0.573   39.512 1.00 33.39  ?  764  TYR   A CA   1 
ATOM   1119 C  C    . TYR   A 1 72  ? 57.151 -0.163  38.834 1.00 38.60  ?  764  TYR   A C    1 
ATOM   1120 O  O    . TYR   A 1 72  ? 58.318 0.228   38.962 1.00 33.95  ?  764  TYR   A O    1 
ATOM   1121 C  CB   . TYR   A 1 72  ? 55.509 -0.191  40.758 1.00 28.36  ?  764  TYR   A CB   1 
ATOM   1122 C  CG   . TYR   A 1 72  ? 56.598 -0.569  41.758 1.00 32.12  ?  764  TYR   A CG   1 
ATOM   1123 C  CD1  . TYR   A 1 72  ? 57.387 -1.720  41.540 1.00 41.50  ?  764  TYR   A CD1  1 
ATOM   1124 C  CD2  . TYR   A 1 72  ? 56.830 0.233   42.893 1.00 24.75  ?  764  TYR   A CD2  1 
ATOM   1125 C  CE1  . TYR   A 1 72  ? 58.413 -2.055  42.440 1.00 27.04  ?  764  TYR   A CE1  1 
ATOM   1126 C  CE2  . TYR   A 1 72  ? 57.848 -0.115  43.801 1.00 35.12  ?  764  TYR   A CE2  1 
ATOM   1127 C  CZ   . TYR   A 1 72  ? 58.647 -1.255  43.567 1.00 33.10  ?  764  TYR   A CZ   1 
ATOM   1128 O  OH   . TYR   A 1 72  ? 59.651 -1.583  44.431 1.00 32.88  ?  764  TYR   A OH   1 
ATOM   1129 H  H    . TYR   A 1 72  ? 53.964 0.525   38.838 1.00 36.69  ?  764  TYR   A H    1 
ATOM   1130 H  HA   . TYR   A 1 72  ? 56.395 1.533   39.849 1.00 35.39  ?  764  TYR   A HA   1 
ATOM   1131 H  HB2  . TYR   A 1 72  ? 54.744 0.378   41.281 1.00 30.36  ?  764  TYR   A HB2  1 
ATOM   1132 H  HB3  . TYR   A 1 72  ? 55.016 -1.114  40.460 1.00 30.36  ?  764  TYR   A HB3  1 
ATOM   1133 H  HD1  . TYR   A 1 72  ? 57.212 -2.340  40.673 1.00 43.50  ?  764  TYR   A HD1  1 
ATOM   1134 H  HD2  . TYR   A 1 72  ? 56.230 1.115   43.068 1.00 26.75  ?  764  TYR   A HD2  1 
ATOM   1135 H  HE1  . TYR   A 1 72  ? 59.021 -2.930  42.263 1.00 29.04  ?  764  TYR   A HE1  1 
ATOM   1136 H  HE2  . TYR   A 1 72  ? 58.024 0.499   44.669 1.00 37.12  ?  764  TYR   A HE2  1 
ATOM   1137 H  HH   . TYR   A 1 72  ? 59.645 -1.058  45.230 1.00 34.88  ?  764  TYR   A HH   1 
ATOM   1138 N  N    . VAL   A 1 73  ? 56.812 -1.234  38.114 1.00 34.69  ?  765  VAL   A N    1 
ATOM   1139 C  CA   . VAL   A 1 73  ? 57.846 -2.040  37.468 1.00 38.57  ?  765  VAL   A CA   1 
ATOM   1140 C  C    . VAL   A 1 73  ? 58.471 -1.293  36.302 1.00 34.45  ?  765  VAL   A C    1 
ATOM   1141 O  O    . VAL   A 1 73  ? 59.698 -1.208  36.212 1.00 34.12  ?  765  VAL   A O    1 
ATOM   1142 C  CB   . VAL   A 1 73  ? 57.316 -3.410  37.022 1.00 42.42  ?  765  VAL   A CB   1 
ATOM   1143 C  CG1  . VAL   A 1 73  ? 58.386 -4.264  36.347 1.00 47.21  ?  765  VAL   A CG1  1 
ATOM   1144 C  CG2  . VAL   A 1 73  ? 56.729 -4.198  38.188 1.00 33.08  ?  765  VAL   A CG2  1 
ATOM   1145 H  H    . VAL   A 1 73  ? 55.835 -1.495  38.024 1.00 36.69  ?  765  VAL   A H    1 
ATOM   1146 H  HA   . VAL   A 1 73  ? 58.640 -2.222  38.197 1.00 40.57  ?  765  VAL   A HA   1 
ATOM   1147 H  HB   . VAL   A 1 73  ? 56.510 -3.250  36.303 1.00 44.42  ?  765  VAL   A HB   1 
ATOM   1148 H  HG11 . VAL   A 1 73  ? 58.025 -5.275  36.162 1.00 49.21  ?  765  VAL   A HG11 1 
ATOM   1149 H  HG12 . VAL   A 1 73  ? 58.691 -3.860  35.380 1.00 49.21  ?  765  VAL   A HG12 1 
ATOM   1150 H  HG13 . VAL   A 1 73  ? 59.278 -4.347  36.968 1.00 49.21  ?  765  VAL   A HG13 1 
ATOM   1151 H  HG21 . VAL   A 1 73  ? 56.326 -5.156  37.857 1.00 35.08  ?  765  VAL   A HG21 1 
ATOM   1152 H  HG22 . VAL   A 1 73  ? 57.484 -4.403  38.948 1.00 35.08  ?  765  VAL   A HG22 1 
ATOM   1153 H  HG23 . VAL   A 1 73  ? 55.912 -3.669  38.674 1.00 35.08  ?  765  VAL   A HG23 1 
ATOM   1154 N  N    . MET   A 1 74  ? 57.631 -0.685  35.466 1.00 32.32  ?  766  MET   A N    1 
ATOM   1155 C  CA   . MET   A 1 74  ? 58.140 0.071   34.323 1.00 37.40  ?  766  MET   A CA   1 
ATOM   1156 C  C    . MET   A 1 74  ? 58.998 1.275   34.686 1.00 39.90  ?  766  MET   A C    1 
ATOM   1157 O  O    . MET   A 1 74  ? 59.884 1.657   33.921 1.00 52.16  ?  766  MET   A O    1 
ATOM   1158 C  CB   . MET   A 1 74  ? 57.018 0.555   33.427 1.00 40.65  ?  766  MET   A CB   1 
ATOM   1159 C  CG   . MET   A 1 74  ? 56.371 -0.505  32.566 1.00 43.62  ?  766  MET   A CG   1 
ATOM   1160 S  SD   . MET   A 1 74  ? 55.197 0.255   31.421 1.00 53.27  ?  766  MET   A SD   1 
ATOM   1161 C  CE   . MET   A 1 74  ? 56.309 0.943   30.210 1.00 50.42  ?  766  MET   A CE   1 
ATOM   1162 H  H    . MET   A 1 74  ? 56.627 -0.745  35.625 1.00 34.32  ?  766  MET   A H    1 
ATOM   1163 H  HA   . MET   A 1 74  ? 58.767 -0.598  33.732 1.00 39.40  ?  766  MET   A HA   1 
ATOM   1164 H  HB2  . MET   A 1 74  ? 56.259 1.074   34.014 1.00 42.65  ?  766  MET   A HB2  1 
ATOM   1165 H  HB3  . MET   A 1 74  ? 57.435 1.281   32.732 1.00 42.65  ?  766  MET   A HB3  1 
ATOM   1166 H  HG2  . MET   A 1 74  ? 57.122 -1.056  31.999 1.00 45.62  ?  766  MET   A HG2  1 
ATOM   1167 H  HG3  . MET   A 1 74  ? 55.842 -1.225  33.191 1.00 45.62  ?  766  MET   A HG3  1 
ATOM   1168 H  HE1  . MET   A 1 74  ? 55.742 1.302   29.353 1.00 52.42  ?  766  MET   A HE1  1 
ATOM   1169 H  HE2  . MET   A 1 74  ? 56.853 1.788   30.621 1.00 52.42  ?  766  MET   A HE2  1 
ATOM   1170 H  HE3  . MET   A 1 74  ? 57.019 0.192   29.862 1.00 52.42  ?  766  MET   A HE3  1 
ATOM   1171 N  N    . ALA   A 1 75  ? 58.745 1.869   35.848 1.00 38.48  ?  767  ALA   A N    1 
ATOM   1172 C  CA   . ALA   A 1 75  ? 59.601 2.947   36.333 1.00 35.29  ?  767  ALA   A CA   1 
ATOM   1173 C  C    . ALA   A 1 75  ? 60.913 2.449   36.942 1.00 33.39  ?  767  ALA   A C    1 
ATOM   1174 O  O    . ALA   A 1 75  ? 61.853 3.224   37.131 1.00 33.34  ?  767  ALA   A O    1 
ATOM   1175 C  CB   . ALA   A 1 75  ? 58.853 3.734   37.397 1.00 30.10  ?  767  ALA   A CB   1 
ATOM   1176 H  H    . ALA   A 1 75  ? 57.948 1.584   36.410 1.00 40.48  ?  767  ALA   A H    1 
ATOM   1177 H  HA   . ALA   A 1 75  ? 59.848 3.632   35.518 1.00 37.29  ?  767  ALA   A HA   1 
ATOM   1178 H  HB1  . ALA   A 1 75  ? 59.457 4.555   37.787 1.00 32.10  ?  767  ALA   A HB1  1 
ATOM   1179 H  HB2  . ALA   A 1 75  ? 57.939 4.170   36.995 1.00 32.10  ?  767  ALA   A HB2  1 
ATOM   1180 H  HB3  . ALA   A 1 75  ? 58.572 3.099   38.238 1.00 32.10  ?  767  ALA   A HB3  1 
ATOM   1181 N  N    . SER   A 1 76  ? 60.981 1.157   37.239 1.00 35.81  ?  768  SER   A N    1 
ATOM   1182 C  CA   . SER   A 1 76  ? 62.142 0.607   37.937 1.00 39.26  ?  768  SER   A CA   1 
ATOM   1183 C  C    . SER   A 1 76  ? 63.178 -0.007  36.997 1.00 41.09  ?  768  SER   A C    1 
ATOM   1184 O  O    . SER   A 1 76  ? 64.310 -0.272  37.408 1.00 48.68  ?  768  SER   A O    1 
ATOM   1185 C  CB   . SER   A 1 76  ? 61.697 -0.485  38.911 1.00 35.80  ?  768  SER   A CB   1 
ATOM   1186 O  OG   . SER   A 1 76  ? 60.854 0.021   39.940 1.00 45.02  ?  768  SER   A OG   1 
ATOM   1187 H  H    . SER   A 1 76  ? 60.206 0.540   37.028 1.00 37.81  ?  768  SER   A H    1 
ATOM   1188 H  HA   . SER   A 1 76  ? 62.658 1.371   38.516 1.00 41.26  ?  768  SER   A HA   1 
ATOM   1189 H  HB2  . SER   A 1 76  ? 61.186 -1.298  38.394 1.00 37.80  ?  768  SER   A HB2  1 
ATOM   1190 H  HB3  . SER   A 1 76  ? 62.567 -0.931  39.398 1.00 37.80  ?  768  SER   A HB3  1 
ATOM   1191 H  HG   . SER   A 1 76  ? 59.995 0.220   39.558 1.00 47.02  ?  768  SER   A HG   1 
ATOM   1192 N  N    . VAL   A 1 77  ? 62.800 -0.250  35.747 1.00 40.28  ?  769  VAL   A N    1 
ATOM   1193 C  CA   . VAL   A 1 77  ? 63.691 -0.885  34.782 1.00 34.66  ?  769  VAL   A CA   1 
ATOM   1194 C  C    . VAL   A 1 77  ? 64.404 0.172   33.945 1.00 40.78  ?  769  VAL   A C    1 
ATOM   1195 O  O    . VAL   A 1 77  ? 63.837 1.209   33.593 1.00 43.05  ?  769  VAL   A O    1 
ATOM   1196 C  CB   . VAL   A 1 77  ? 62.888 -1.847  33.882 1.00 38.00  ?  769  VAL   A CB   1 
ATOM   1197 C  CG1  . VAL   A 1 77  ? 62.468 -3.100  34.645 1.00 26.72  ?  769  VAL   A CG1  1 
ATOM   1198 C  CG2  . VAL   A 1 77  ? 61.665 -1.218  33.218 1.00 26.69  ?  769  VAL   A CG2  1 
ATOM   1199 H  H    . VAL   A 1 77  ? 61.879 0.031   35.443 1.00 42.28  ?  769  VAL   A H    1 
ATOM   1200 H  HA   . VAL   A 1 77  ? 64.454 -1.478  35.292 1.00 36.66  ?  769  VAL   A HA   1 
ATOM   1201 H  HB   . VAL   A 1 77  ? 63.546 -2.180  33.077 1.00 40.00  ?  769  VAL   A HB   1 
ATOM   1202 H  HG11 . VAL   A 1 77  ? 61.950 -3.805  33.993 1.00 28.72  ?  769  VAL   A HG11 1 
ATOM   1203 H  HG12 . VAL   A 1 77  ? 63.327 -3.621  35.070 1.00 28.72  ?  769  VAL   A HG12 1 
ATOM   1204 H  HG13 . VAL   A 1 77  ? 61.790 -2.861  35.466 1.00 28.72  ?  769  VAL   A HG13 1 
ATOM   1205 H  HG21 . VAL   A 1 77  ? 61.092 -1.949  32.648 1.00 28.69  ?  769  VAL   A HG21 1 
ATOM   1206 H  HG22 . VAL   A 1 77  ? 60.986 -0.803  33.956 1.00 28.69  ?  769  VAL   A HG22 1 
ATOM   1207 H  HG23 . VAL   A 1 77  ? 61.935 -0.413  32.534 1.00 28.69  ?  769  VAL   A HG23 1 
ATOM   1208 N  N    . ASP   A 1 78  ? 65.652 -0.117  33.606 1.00 34.45  ?  770  ASP   A N    1 
ATOM   1209 C  CA   . ASP   A 1 78  ? 66.447 0.758   32.755 1.00 33.97  ?  770  ASP   A CA   1 
ATOM   1210 C  C    . ASP   A 1 78  ? 67.390 -0.081  31.904 1.00 32.62  ?  770  ASP   A C    1 
ATOM   1211 O  O    . ASP   A 1 78  ? 68.482 -0.440  32.341 1.00 32.21  ?  770  ASP   A O    1 
ATOM   1212 C  CB   . ASP   A 1 78  ? 67.128 1.852   33.576 1.00 30.44  ?  770  ASP   A CB   1 
ATOM   1213 C  CG   . ASP   A 1 78  ? 67.984 2.799   32.757 1.00 39.28  ?  770  ASP   A CG   1 
ATOM   1214 O  OD1  . ASP   A 1 78  ? 67.645 3.063   31.582 1.00 41.26  ?  770  ASP   A OD1  1 
ATOM   1215 O  OD2  . ASP   A 1 78  ? 69.003 3.292   33.283 1.00 52.43  -1 770  ASP   A OD2  1 
ATOM   1216 H  H    . ASP   A 1 78  ? 66.108 -0.953  33.965 1.00 36.45  ?  770  ASP   A H    1 
ATOM   1217 H  HA   . ASP   A 1 78  ? 65.789 1.280   32.060 1.00 35.97  ?  770  ASP   A HA   1 
ATOM   1218 H  HB2  . ASP   A 1 78  ? 66.380 2.452   34.094 1.00 32.44  ?  770  ASP   A HB2  1 
ATOM   1219 H  HB3  . ASP   A 1 78  ? 67.754 1.399   34.347 1.00 32.44  ?  770  ASP   A HB3  1 
ATOM   1220 N  N    . ASN   A 1 79  ? 66.965 -0.425  30.698 1.00 32.76  ?  771  ASN   A N    1 
ATOM   1221 C  CA   . ASN   A 1 79  ? 67.776 -1.242  29.794 1.00 31.14  ?  771  ASN   A CA   1 
ATOM   1222 C  C    . ASN   A 1 79  ? 67.363 -0.944  28.361 1.00 22.02  ?  771  ASN   A C    1 
ATOM   1223 O  O    . ASN   A 1 79  ? 66.162 -0.800  28.128 1.00 20.26  ?  771  ASN   A O    1 
ATOM   1224 C  CB   . ASN   A 1 79  ? 67.699 -2.737  30.140 1.00 31.40  ?  771  ASN   A CB   1 
ATOM   1225 C  CG   . ASN   A 1 79  ? 68.487 -3.624  29.193 1.00 42.43  ?  771  ASN   A CG   1 
ATOM   1226 O  OD1  . ASN   A 1 79  ? 67.989 -4.060  28.157 1.00 36.30  ?  771  ASN   A OD1  1 
ATOM   1227 N  ND2  . ASN   A 1 79  ? 69.728 -3.890  29.529 1.00 31.86  ?  771  ASN   A ND2  1 
ATOM   1228 H  H    . ASN   A 1 79  ? 66.058 -0.078  30.368 1.00 34.76  ?  771  ASN   A H    1 
ATOM   1229 H  HA   . ASN   A 1 79  ? 68.811 -0.933  29.930 1.00 33.14  ?  771  ASN   A HA   1 
ATOM   1230 H  HB2  . ASN   A 1 79  ? 68.052 -2.889  31.156 1.00 33.40  ?  771  ASN   A HB2  1 
ATOM   1231 H  HB3  . ASN   A 1 79  ? 66.660 -3.068  30.129 1.00 33.40  ?  771  ASN   A HB3  1 
ATOM   1232 H  HD21 . ASN   A 1 79  ? 70.112 -3.520  30.385 1.00 33.86  ?  771  ASN   A HD21 1 
ATOM   1233 H  HD22 . ASN   A 1 79  ? 70.305 -4.466  28.915 1.00 33.86  ?  771  ASN   A HD22 1 
ATOM   1234 N  N    . PRO   A 1 80  ? 68.284 -0.915  27.375 1.00 28.11  ?  772  PRO   A N    1 
ATOM   1235 C  CA   . PRO   A 1 80  ? 67.928 -0.716  25.974 1.00 19.45  ?  772  PRO   A CA   1 
ATOM   1236 C  C    . PRO   A 1 80  ? 66.899 -1.647  25.362 1.00 24.49  ?  772  PRO   A C    1 
ATOM   1237 O  O    . PRO   A 1 80  ? 66.315 -1.287  24.343 1.00 31.70  ?  772  PRO   A O    1 
ATOM   1238 C  CB   . PRO   A 1 80  ? 69.233 -0.827  25.203 1.00 26.25  ?  772  PRO   A CB   1 
ATOM   1239 C  CG   . PRO   A 1 80  ? 70.319 -0.472  26.214 1.00 20.66  ?  772  PRO   A CG   1 
ATOM   1240 C  CD   . PRO   A 1 80  ? 69.742 -0.860  27.581 1.00 20.19  ?  772  PRO   A CD   1 
ATOM   1241 H  HA   . PRO   A 1 80  ? 67.549 0.304   25.887 1.00 21.45  ?  772  PRO   A HA   1 
ATOM   1242 H  HB2  . PRO   A 1 80  ? 69.397 -1.849  24.853 1.00 28.25  ?  772  PRO   A HB2  1 
ATOM   1243 H  HB3  . PRO   A 1 80  ? 69.253 -0.181  24.324 1.00 28.25  ?  772  PRO   A HB3  1 
ATOM   1244 H  HG2  . PRO   A 1 80  ? 71.271 -0.961  26.001 1.00 22.66  ?  772  PRO   A HG2  1 
ATOM   1245 H  HG3  . PRO   A 1 80  ? 70.493 0.605   26.187 1.00 22.66  ?  772  PRO   A HG3  1 
ATOM   1246 H  HD2  . PRO   A 1 80  ? 70.130 -1.833  27.875 1.00 22.19  ?  772  PRO   A HD2  1 
ATOM   1247 H  HD3  . PRO   A 1 80  ? 70.038 -0.124  28.330 1.00 22.19  ?  772  PRO   A HD3  1 
ATOM   1248 N  N    . HIS   A 1 81  ? 66.657 -2.803  25.969 1.00 26.51  ?  773  HIS   A N    1 
ATOM   1249 C  CA   . HIS   A 1 81  ? 65.720 -3.789  25.425 1.00 31.02  ?  773  HIS   A CA   1 
ATOM   1250 C  C    . HIS   A 1 81  ? 64.526 -4.021  26.318 1.00 29.55  ?  773  HIS   A C    1 
ATOM   1251 O  O    . HIS   A 1 81  ? 63.814 -5.020  26.174 1.00 26.23  ?  773  HIS   A O    1 
ATOM   1252 C  CB   . HIS   A 1 81  ? 66.433 -5.068  25.005 1.00 25.87  ?  773  HIS   A CB   1 
ATOM   1253 C  CG   . HIS   A 1 81  ? 67.501 -4.756  23.995 1.00 30.21  ?  773  HIS   A CG   1 
ATOM   1254 N  ND1  . HIS   A 1 81  ? 67.219 -4.251  22.727 1.00 31.60  ?  773  HIS   A ND1  1 
ATOM   1255 C  CD2  . HIS   A 1 81  ? 68.890 -4.841  24.050 1.00 30.65  ?  773  HIS   A CD2  1 
ATOM   1256 C  CE1  . HIS   A 1 81  ? 68.371 -4.047  22.121 1.00 31.16  ?  773  HIS   A CE1  1 
ATOM   1257 N  NE2  . HIS   A 1 81  ? 69.423 -4.378  22.837 1.00 36.51  ?  773  HIS   A NE2  1 
ATOM   1258 H  H    . HIS   A 1 81  ? 67.179 -3.076  26.797 1.00 28.51  ?  773  HIS   A H    1 
ATOM   1259 H  HA   . HIS   A 1 81  ? 65.264 -3.421  24.509 1.00 33.02  ?  773  HIS   A HA   1 
ATOM   1260 H  HB2  . HIS   A 1 81  ? 66.893 -5.550  25.869 1.00 27.87  ?  773  HIS   A HB2  1 
ATOM   1261 H  HB3  . HIS   A 1 81  ? 65.739 -5.789  24.571 1.00 27.87  ?  773  HIS   A HB3  1 
ATOM   1262 H  HD1  . HIS   A 1 81  ? 66.292 -4.068  22.341 1.00 33.60  ?  773  HIS   A HD1  1 
ATOM   1263 H  HD2  . HIS   A 1 81  ? 69.528 -5.178  24.853 1.00 32.65  ?  773  HIS   A HD2  1 
ATOM   1264 H  HE1  . HIS   A 1 81  ? 68.445 -3.645  21.118 1.00 33.16  ?  773  HIS   A HE1  1 
ATOM   1265 N  N    . VAL   A 1 82  ? 64.263 -3.059  27.197 1.00 30.38  ?  774  VAL   A N    1 
ATOM   1266 C  CA   . VAL   A 1 82  ? 63.104 -3.100  28.072 1.00 36.64  ?  774  VAL   A CA   1 
ATOM   1267 C  C    . VAL   A 1 82  ? 62.411 -1.747  27.985 1.00 36.62  ?  774  VAL   A C    1 
ATOM   1268 O  O    . VAL   A 1 82  ? 63.065 -0.704  28.069 1.00 34.54  ?  774  VAL   A O    1 
ATOM   1269 C  CB   . VAL   A 1 82  ? 63.523 -3.504  29.497 1.00 35.62  ?  774  VAL   A CB   1 
ATOM   1270 C  CG1  . VAL   A 1 82  ? 62.351 -3.457  30.456 1.00 29.24  ?  774  VAL   A CG1  1 
ATOM   1271 C  CG2  . VAL   A 1 82  ? 64.185 -4.880  29.552 1.00 31.58  ?  774  VAL   A CG2  1 
ATOM   1272 H  H    . VAL   A 1 82  ? 64.857 -2.235  27.252 1.00 32.38  ?  774  VAL   A H    1 
ATOM   1273 H  HA   . VAL   A 1 82  ? 62.380 -3.839  27.719 1.00 38.64  ?  774  VAL   A HA   1 
ATOM   1274 H  HB   . VAL   A 1 82  ? 64.254 -2.777  29.858 1.00 37.62  ?  774  VAL   A HB   1 
ATOM   1275 H  HG11 . VAL   A 1 82  ? 62.574 -3.918  31.417 1.00 31.24  ?  774  VAL   A HG11 1 
ATOM   1276 H  HG12 . VAL   A 1 82  ? 62.047 -2.429  30.654 1.00 31.24  ?  774  VAL   A HG12 1 
ATOM   1277 H  HG13 . VAL   A 1 82  ? 61.496 -3.955  30.007 1.00 31.24  ?  774  VAL   A HG13 1 
ATOM   1278 H  HG21 . VAL   A 1 82  ? 64.391 -5.185  30.577 1.00 33.58  ?  774  VAL   A HG21 1 
ATOM   1279 H  HG22 . VAL   A 1 82  ? 63.553 -5.648  29.104 1.00 33.58  ?  774  VAL   A HG22 1 
ATOM   1280 H  HG23 . VAL   A 1 82  ? 65.141 -4.888  29.027 1.00 33.58  ?  774  VAL   A HG23 1 
ATOM   1281 N  N    . CYS   A 1 83  ? 61.092 -1.748  27.843 1.00 38.19  ?  775  CYS   A N    1 
ATOM   1282 C  CA   . CYS   A 1 83  ? 60.354 -0.487  27.896 1.00 43.68  ?  775  CYS   A CA   1 
ATOM   1283 C  C    . CYS   A 1 83  ? 60.283 0.125   29.294 1.00 42.61  ?  775  CYS   A C    1 
ATOM   1284 O  O    . CYS   A 1 83  ? 59.893 -0.541  30.254 1.00 51.67  ?  775  CYS   A O    1 
ATOM   1285 C  CB   . CYS   A 1 83  ? 58.939 -0.678  27.381 1.00 49.65  ?  775  CYS   A CB   1 
ATOM   1286 S  SG   . CYS   A 1 83  ? 58.815 -0.803  25.580 1.00 57.75  ?  775  CYS   A SG   1 
ATOM   1287 H  H    . CYS   A 1 83  ? 60.577 -2.624  27.791 1.00 40.19  ?  775  CYS   A H    1 
ATOM   1288 H  HA   . CYS   A 1 83  ? 60.842 0.233   27.234 1.00 45.68  ?  775  CYS   A HA   1 
ATOM   1289 H  HB2  . CYS   A 1 83  ? 58.465 -1.546  27.843 1.00 51.65  ?  775  CYS   A HB2  1 
ATOM   1290 H  HB3  . CYS   A 1 83  ? 58.339 0.185   27.666 1.00 51.65  ?  775  CYS   A HB3  1 
ATOM   1291 H  HG   . CYS   A 1 83  ? 59.453 -1.976  25.494 1.00 59.75  ?  775  CYS   A HG   1 
ATOM   1292 N  N    . ARG   A 1 84  ? 60.632 1.402   29.382 1.00 39.06  ?  776  ARG   A N    1 
ATOM   1293 C  CA   . ARG   A 1 84  ? 60.549 2.161   30.629 1.00 49.14  ?  776  ARG   A CA   1 
ATOM   1294 C  C    . ARG   A 1 84  ? 59.338 3.109   30.603 1.00 48.88  ?  776  ARG   A C    1 
ATOM   1295 O  O    . ARG   A 1 84  ? 58.855 3.520   29.541 1.00 46.17  ?  776  ARG   A O    1 
ATOM   1296 C  CB   . ARG   A 1 84  ? 61.877 2.910   30.845 1.00 44.95  ?  776  ARG   A CB   1 
ATOM   1297 C  CG   . ARG   A 1 84  ? 61.875 3.918   31.984 1.00 68.15  ?  776  ARG   A CG   1 
ATOM   1298 C  CD   . ARG   A 1 84  ? 63.212 4.313   32.593 1.00 75.37  ?  776  ARG   A CD   1 
ATOM   1299 N  NE   . ARG   A 1 84  ? 62.970 4.648   34.010 1.00 103.16 ?  776  ARG   A NE   1 
ATOM   1300 C  CZ   . ARG   A 1 84  ? 62.555 5.857   34.437 1.00 106.17 ?  776  ARG   A CZ   1 
ATOM   1301 N  NH1  . ARG   A 1 84  ? 62.381 6.864   33.565 1.00 93.99  ?  776  ARG   A NH1  1 
ATOM   1302 N  NH2  . ARG   A 1 84  ? 62.312 6.051   35.741 1.00 97.59  1  776  ARG   A NH2  1 
ATOM   1303 H  H    . ARG   A 1 84  ? 60.880 1.910   28.546 1.00 41.06  ?  776  ARG   A H    1 
ATOM   1304 H  HA   . ARG   A 1 84  ? 60.418 1.487   31.476 1.00 51.14  ?  776  ARG   A HA   1 
ATOM   1305 H  HB2  . ARG   A 1 84  ? 62.640 2.167   31.060 1.00 46.95  ?  776  ARG   A HB2  1 
ATOM   1306 H  HB3  . ARG   A 1 84  ? 62.191 3.414   29.930 1.00 46.95  ?  776  ARG   A HB3  1 
ATOM   1307 H  HG2  . ARG   A 1 84  ? 61.393 4.829   31.632 1.00 70.15  ?  776  ARG   A HG2  1 
ATOM   1308 H  HG3  . ARG   A 1 84  ? 61.254 3.526   32.788 1.00 70.15  ?  776  ARG   A HG3  1 
ATOM   1309 H  HD2  . ARG   A 1 84  ? 63.913 3.481   32.563 1.00 77.37  ?  776  ARG   A HD2  1 
ATOM   1310 H  HD3  . ARG   A 1 84  ? 63.691 5.130   32.056 1.00 77.37  ?  776  ARG   A HD3  1 
ATOM   1311 H  HE   . ARG   A 1 84  ? 63.093 3.903   34.685 1.00 105.16 ?  776  ARG   A HE   1 
ATOM   1312 H  HH11 . ARG   A 1 84  ? 62.562 6.717   32.579 1.00 95.99  ?  776  ARG   A HH11 1 
ATOM   1313 H  HH12 . ARG   A 1 84  ? 62.061 7.764   33.885 1.00 95.99  ?  776  ARG   A HH12 1 
ATOM   1314 H  HH21 . ARG   A 1 84  ? 62.424 5.286   36.396 1.00 99.59  ?  776  ARG   A HH21 1 
ATOM   1315 H  HH22 . ARG   A 1 84  ? 62.000 6.951   36.076 1.00 99.59  ?  776  ARG   A HH22 1 
ATOM   1316 N  N    . LEU   A 1 85  ? 58.849 3.444   31.795 1.00 42.74  ?  777  LEU   A N    1 
ATOM   1317 C  CA   . LEU   A 1 85  ? 57.847 4.492   31.976 1.00 37.53  ?  777  LEU   A CA   1 
ATOM   1318 C  C    . LEU   A 1 85  ? 58.539 5.845   32.059 1.00 39.57  ?  777  LEU   A C    1 
ATOM   1319 O  O    . LEU   A 1 85  ? 59.518 6.009   32.792 1.00 44.59  ?  777  LEU   A O    1 
ATOM   1320 C  CB   . LEU   A 1 85  ? 57.130 4.253   33.300 1.00 40.00  ?  777  LEU   A CB   1 
ATOM   1321 C  CG   . LEU   A 1 85  ? 55.920 5.126   33.611 1.00 48.56  ?  777  LEU   A CG   1 
ATOM   1322 C  CD1  . LEU   A 1 85  ? 54.694 4.730   32.815 1.00 45.96  ?  777  LEU   A CD1  1 
ATOM   1323 C  CD2  . LEU   A 1 85  ? 55.614 5.074   35.093 1.00 46.39  ?  777  LEU   A CD2  1 
ATOM   1324 H  H    . LEU   A 1 85  ? 59.302 3.069   32.623 1.00 44.74  ?  777  LEU   A H    1 
ATOM   1325 H  HA   . LEU   A 1 85  ? 57.126 4.473   31.156 1.00 39.53  ?  777  LEU   A HA   1 
ATOM   1326 H  HB2  . LEU   A 1 85  ? 56.788 3.226   33.349 1.00 42.00  ?  777  LEU   A HB2  1 
ATOM   1327 H  HB3  . LEU   A 1 85  ? 57.855 4.347   34.112 1.00 42.00  ?  777  LEU   A HB3  1 
ATOM   1328 H  HG   . LEU   A 1 85  ? 56.143 6.166   33.380 1.00 50.56  ?  777  LEU   A HG   1 
ATOM   1329 H  HD11 . LEU   A 1 85  ? 53.860 5.384   33.071 1.00 47.96  ?  777  LEU   A HD11 1 
ATOM   1330 H  HD12 . LEU   A 1 85  ? 54.861 4.834   31.746 1.00 47.96  ?  777  LEU   A HD12 1 
ATOM   1331 H  HD13 . LEU   A 1 85  ? 54.390 3.702   33.014 1.00 47.96  ?  777  LEU   A HD13 1 
ATOM   1332 H  HD21 . LEU   A 1 85  ? 54.699 5.612   35.311 1.00 48.39  ?  777  LEU   A HD21 1 
ATOM   1333 H  HD22 . LEU   A 1 85  ? 55.488 4.050   35.441 1.00 48.39  ?  777  LEU   A HD22 1 
ATOM   1334 H  HD23 . LEU   A 1 85  ? 56.411 5.532   35.679 1.00 48.39  ?  777  LEU   A HD23 1 
ATOM   1335 N  N    . LEU   A 1 86  ? 58.009 6.825   31.338 1.00 30.64  ?  778  LEU   A N    1 
ATOM   1336 C  CA   . LEU   A 1 86  ? 58.555 8.176   31.441 1.00 33.43  ?  778  LEU   A CA   1 
ATOM   1337 C  C    . LEU   A 1 86  ? 57.942 8.920   32.630 1.00 34.74  ?  778  LEU   A C    1 
ATOM   1338 O  O    . LEU   A 1 86  ? 58.651 9.580   33.394 1.00 36.86  ?  778  LEU   A O    1 
ATOM   1339 C  CB   . LEU   A 1 86  ? 58.276 8.953   30.155 1.00 40.20  ?  778  LEU   A CB   1 
ATOM   1340 C  CG   . LEU   A 1 86  ? 58.647 8.211   28.868 1.00 41.52  ?  778  LEU   A CG   1 
ATOM   1341 C  CD1  . LEU   A 1 86  ? 58.370 9.063   27.652 1.00 50.28  ?  778  LEU   A CD1  1 
ATOM   1342 C  CD2  . LEU   A 1 86  ? 60.089 7.733   28.837 1.00 47.52  ?  778  LEU   A CD2  1 
ATOM   1343 H  H    . LEU   A 1 86  ? 57.139 6.690   30.832 1.00 32.64  ?  778  LEU   A H    1 
ATOM   1344 H  HA   . LEU   A 1 86  ? 59.637 8.151   31.587 1.00 35.43  ?  778  LEU   A HA   1 
ATOM   1345 H  HB2  . LEU   A 1 86  ? 57.218 9.220   30.106 1.00 42.20  ?  778  LEU   A HB2  1 
ATOM   1346 H  HB3  . LEU   A 1 86  ? 58.814 9.902   30.199 1.00 42.20  ?  778  LEU   A HB3  1 
ATOM   1347 H  HG   . LEU   A 1 86  ? 58.007 7.333   28.783 1.00 43.52  ?  778  LEU   A HG   1 
ATOM   1348 H  HD11 . LEU   A 1 86  ? 58.492 8.490   26.732 1.00 52.28  ?  778  LEU   A HD11 1 
ATOM   1349 H  HD12 . LEU   A 1 86  ? 57.350 9.440   27.676 1.00 52.28  ?  778  LEU   A HD12 1 
ATOM   1350 H  HD13 . LEU   A 1 86  ? 59.041 9.920   27.598 1.00 52.28  ?  778  LEU   A HD13 1 
ATOM   1351 H  HD21 . LEU   A 1 86  ? 60.301 7.200   27.910 1.00 49.52  ?  778  LEU   A HD21 1 
ATOM   1352 H  HD22 . LEU   A 1 86  ? 60.791 8.563   28.918 1.00 49.52  ?  778  LEU   A HD22 1 
ATOM   1353 H  HD23 . LEU   A 1 86  ? 60.308 7.035   29.645 1.00 49.52  ?  778  LEU   A HD23 1 
ATOM   1354 N  N    . GLY   A 1 87  ? 56.637 8.765   32.826 1.00 32.68  ?  779  GLY   A N    1 
ATOM   1355 C  CA   . GLY   A 1 87  ? 55.999 9.302   34.016 1.00 36.73  ?  779  GLY   A CA   1 
ATOM   1356 C  C    . GLY   A 1 87  ? 54.528 8.953   34.072 1.00 39.23  ?  779  GLY   A C    1 
ATOM   1357 O  O    . GLY   A 1 87  ? 54.014 8.209   33.227 1.00 33.18  ?  779  GLY   A O    1 
ATOM   1358 H  H    . GLY   A 1 87  ? 56.075 8.194   32.205 1.00 34.68  ?  779  GLY   A H    1 
ATOM   1359 H  HA2  . GLY   A 1 87  ? 56.481 8.898   34.908 1.00 38.73  ?  779  GLY   A HA2  1 
ATOM   1360 H  HA3  . GLY   A 1 87  ? 56.116 10.386  34.043 1.00 38.73  ?  779  GLY   A HA3  1 
ATOM   1361 N  N    . ILE   A 1 88  ? 53.857 9.505   35.074 1.00 40.17  ?  780  ILE   A N    1 
ATOM   1362 C  CA   . ILE   A 1 88  ? 52.411 9.348   35.248 1.00 42.93  ?  780  ILE   A CA   1 
ATOM   1363 C  C    . ILE   A 1 88  ? 51.733 10.704  35.336 1.00 40.84  ?  780  ILE   A C    1 
ATOM   1364 O  O    . ILE   A 1 88  ? 52.359 11.711  35.662 1.00 43.40  ?  780  ILE   A O    1 
ATOM   1365 C  CB   . ILE   A 1 88  ? 52.055 8.458   36.453 1.00 44.73  ?  780  ILE   A CB   1 
ATOM   1366 C  CG1  . ILE   A 1 88  ? 52.572 9.006   37.783 1.00 49.32  ?  780  ILE   A CG1  1 
ATOM   1367 C  CG2  . ILE   A 1 88  ? 52.534 7.039   36.238 1.00 59.91  ?  780  ILE   A CG2  1 
ATOM   1368 C  CD1  . ILE   A 1 88  ? 52.149 8.196   38.994 1.00 61.57  ?  780  ILE   A CD1  1 
ATOM   1369 H  H    . ILE   A 1 88  ? 54.353 10.108  35.728 1.00 42.17  ?  780  ILE   A H    1 
ATOM   1370 H  HA   . ILE   A 1 88  ? 51.991 8.882   34.358 1.00 44.93  ?  780  ILE   A HA   1 
ATOM   1371 H  HB   . ILE   A 1 88  ? 50.966 8.414   36.512 1.00 46.73  ?  780  ILE   A HB   1 
ATOM   1372 H  HG12 . ILE   A 1 88  ? 53.662 9.079   37.766 1.00 51.32  ?  780  ILE   A HG12 1 
ATOM   1373 H  HG13 . ILE   A 1 88  ? 52.211 10.023  37.926 1.00 51.32  ?  780  ILE   A HG13 1 
ATOM   1374 H  HG21 . ILE   A 1 88  ? 51.991 6.329   36.862 1.00 61.91  ?  780  ILE   A HG21 1 
ATOM   1375 H  HG22 . ILE   A 1 88  ? 52.415 6.736   35.200 1.00 61.91  ?  780  ILE   A HG22 1 
ATOM   1376 H  HG23 . ILE   A 1 88  ? 53.589 6.967   36.491 1.00 61.91  ?  780  ILE   A HG23 1 
ATOM   1377 H  HD11 . ILE   A 1 88  ? 52.525 8.671   39.900 1.00 63.57  ?  780  ILE   A HD11 1 
ATOM   1378 H  HD12 . ILE   A 1 88  ? 51.065 8.128   39.075 1.00 63.57  ?  780  ILE   A HD12 1 
ATOM   1379 H  HD13 . ILE   A 1 88  ? 52.548 7.183   38.970 1.00 63.57  ?  780  ILE   A HD13 1 
ATOM   1380 N  N    . CYS   A 1 89  ? 50.437 10.722  35.086 1.00 41.15  ?  781  CYS   A N    1 
ATOM   1381 C  CA   . CYS   A 1 89  ? 49.650 11.929  35.279 1.00 44.32  ?  781  CYS   A CA   1 
ATOM   1382 C  C    . CYS   A 1 89  ? 48.429 11.551  36.090 1.00 39.98  ?  781  CYS   A C    1 
ATOM   1383 O  O    . CYS   A 1 89  ? 47.678 10.655  35.688 1.00 45.60  ?  781  CYS   A O    1 
ATOM   1384 C  CB   . CYS   A 1 89  ? 49.313 12.562  33.938 1.00 41.21  ?  781  CYS   A CB   1 
ATOM   1385 S  SG   . CYS   A 1 89  ? 48.520 14.178  34.025 1.00 58.64  ?  781  CYS   A SG   1 
ATOM   1386 H  H    . CYS   A 1 89  ? 49.970 9.876   34.773 1.00 43.15  ?  781  CYS   A H    1 
ATOM   1387 H  HA   . CYS   A 1 89  ? 50.198 12.678  35.856 1.00 46.32  ?  781  CYS   A HA   1 
ATOM   1388 H  HB2  . CYS   A 1 89  ? 50.220 12.678  33.344 1.00 43.21  ?  781  CYS   A HB2  1 
ATOM   1389 H  HB3  . CYS   A 1 89  ? 48.651 11.908  33.373 1.00 43.21  ?  781  CYS   A HB3  1 
ATOM   1390 H  HG   . CYS   A 1 89  ? 49.587 14.789  34.573 1.00 60.64  ?  781  CYS   A HG   1 
ATOM   1391 N  N    . LEU   A 1 90  ? 48.227 12.225  37.221 1.00 41.36  ?  782  LEU   A N    1 
ATOM   1392 C  CA   . LEU   A 1 90  ? 47.120 11.891  38.114 1.00 56.91  ?  782  LEU   A CA   1 
ATOM   1393 C  C    . LEU   A 1 90  ? 45.930 12.802  37.857 1.00 63.05  ?  782  LEU   A C    1 
ATOM   1394 O  O    . LEU   A 1 90  ? 45.457 13.560  38.706 1.00 71.17  ?  782  LEU   A O    1 
ATOM   1395 C  CB   . LEU   A 1 90  ? 47.542 11.929  39.583 1.00 52.74  ?  782  LEU   A CB   1 
ATOM   1396 C  CG   . LEU   A 1 90  ? 48.364 10.717  40.020 1.00 50.28  ?  782  LEU   A CG   1 
ATOM   1397 C  CD1  . LEU   A 1 90  ? 49.853 10.959  39.857 1.00 66.91  ?  782  LEU   A CD1  1 
ATOM   1398 C  CD2  . LEU   A 1 90  ? 48.032 10.334  41.453 1.00 69.28  ?  782  LEU   A CD2  1 
ATOM   1399 H  H    . LEU   A 1 90  ? 48.846 12.983  37.486 1.00 43.36  ?  782  LEU   A H    1 
ATOM   1400 H  HA   . LEU   A 1 90  ? 46.749 10.882  37.926 1.00 58.91  ?  782  LEU   A HA   1 
ATOM   1401 H  HB2  . LEU   A 1 90  ? 48.053 12.864  39.820 1.00 54.74  ?  782  LEU   A HB2  1 
ATOM   1402 H  HB3  . LEU   A 1 90  ? 46.638 11.947  40.194 1.00 54.74  ?  782  LEU   A HB3  1 
ATOM   1403 H  HG   . LEU   A 1 90  ? 48.094 9.858   39.404 1.00 52.28  ?  782  LEU   A HG   1 
ATOM   1404 H  HD11 . LEU   A 1 90  ? 50.436 10.113  40.215 1.00 68.91  ?  782  LEU   A HD11 1 
ATOM   1405 H  HD12 . LEU   A 1 90  ? 50.126 11.118  38.814 1.00 68.91  ?  782  LEU   A HD12 1 
ATOM   1406 H  HD13 . LEU   A 1 90  ? 50.173 11.836  40.419 1.00 68.91  ?  782  LEU   A HD13 1 
ATOM   1407 H  HD21 . LEU   A 1 90  ? 48.489 9.383   41.723 1.00 71.28  ?  782  LEU   A HD21 1 
ATOM   1408 H  HD22 . LEU   A 1 90  ? 48.364 11.087  42.169 1.00 71.28  ?  782  LEU   A HD22 1 
ATOM   1409 H  HD23 . LEU   A 1 90  ? 46.960 10.197  41.596 1.00 71.28  ?  782  LEU   A HD23 1 
ATOM   1410 N  N    . THR   A 1 91  ? 45.425 12.678  36.644 1.00 60.66  ?  783  THR   A N    1 
ATOM   1411 C  CA   . THR   A 1 91  ? 44.086 13.141  36.313 1.00 56.96  ?  783  THR   A CA   1 
ATOM   1412 C  C    . THR   A 1 91  ? 43.052 12.115  36.783 1.00 62.22  ?  783  THR   A C    1 
ATOM   1413 O  O    . THR   A 1 91  ? 43.386 11.114  37.427 1.00 64.04  ?  783  THR   A O    1 
ATOM   1414 C  CB   . THR   A 1 91  ? 44.019 13.417  34.796 1.00 44.01  ?  783  THR   A CB   1 
ATOM   1415 O  OG1  . THR   A 1 91  ? 44.545 12.368  33.980 1.00 52.74  ?  783  THR   A OG1  1 
ATOM   1416 C  CG2  . THR   A 1 91  ? 44.757 14.695  34.441 1.00 37.74  ?  783  THR   A CG2  1 
ATOM   1417 H  H    . THR   A 1 91  ? 45.877 12.064  35.979 1.00 62.66  ?  783  THR   A H    1 
ATOM   1418 H  HA   . THR   A 1 91  ? 43.865 14.072  36.841 1.00 58.96  ?  783  THR   A HA   1 
ATOM   1419 H  HB   . THR   A 1 91  ? 42.982 13.563  34.490 1.00 46.01  ?  783  THR   A HB   1 
ATOM   1420 H  HG1  . THR   A 1 91  ? 44.084 11.543  34.151 1.00 54.74  ?  783  THR   A HG1  1 
ATOM   1421 H  HG21 . THR   A 1 91  ? 44.728 14.883  33.369 1.00 39.74  ?  783  THR   A HG21 1 
ATOM   1422 H  HG22 . THR   A 1 91  ? 44.311 15.559  34.935 1.00 39.74  ?  783  THR   A HG22 1 
ATOM   1423 H  HG23 . THR   A 1 91  ? 45.802 14.657  34.745 1.00 39.74  ?  783  THR   A HG23 1 
ATOM   1424 N  N    . SER   A 1 92  ? 41.780 12.382  36.493 1.00 65.34  ?  784  SER   A N    1 
ATOM   1425 C  CA   . SER   A 1 92  ? 40.661 11.580  36.989 1.00 65.05  ?  784  SER   A CA   1 
ATOM   1426 C  C    . SER   A 1 92  ? 40.730 10.109  36.610 1.00 64.81  ?  784  SER   A C    1 
ATOM   1427 O  O    . SER   A 1 92  ? 40.585 9.216   37.447 1.00 67.10  ?  784  SER   A O    1 
ATOM   1428 C  CB   . SER   A 1 92  ? 39.340 12.173  36.498 1.00 66.06  ?  784  SER   A CB   1 
ATOM   1429 O  OG   . SER   A 1 92  ? 39.215 13.555  36.811 1.00 83.14  ?  784  SER   A OG   1 
ATOM   1430 H  H    . SER   A 1 92  ? 41.531 13.249  36.039 1.00 67.34  ?  784  SER   A H    1 
ATOM   1431 H  HA   . SER   A 1 92  ? 40.676 11.629  38.077 1.00 67.05  ?  784  SER   A HA   1 
ATOM   1432 H  HB2  . SER   A 1 92  ? 39.243 12.060  35.416 1.00 68.06  ?  784  SER   A HB2  1 
ATOM   1433 H  HB3  . SER   A 1 92  ? 38.499 11.635  36.940 1.00 68.06  ?  784  SER   A HB3  1 
ATOM   1434 H  HG   . SER   A 1 92  ? 39.166 13.650  37.754 1.00 85.14  ?  784  SER   A HG   1 
ATOM   1435 N  N    . THR   A 1 93  ? 41.018 9.888   35.338 1.00 70.86  ?  785  THR   A N    1 
ATOM   1436 C  CA   . THR   A 1 93  ? 41.572 8.633   34.914 1.00 75.90  ?  785  THR   A CA   1 
ATOM   1437 C  C    . THR   A 1 93  ? 43.071 8.882   34.833 1.00 68.47  ?  785  THR   A C    1 
ATOM   1438 O  O    . THR   A 1 93  ? 43.512 9.861   34.221 1.00 62.94  ?  785  THR   A O    1 
ATOM   1439 C  CB   . THR   A 1 93  ? 40.911 8.244   33.585 1.00 78.06  ?  785  THR   A CB   1 
ATOM   1440 O  OG1  . THR   A 1 93  ? 41.483 7.075   33.056 1.00 87.82  ?  785  THR   A OG1  1 
ATOM   1441 C  CG2  . THR   A 1 93  ? 40.905 9.292   32.482 1.00 76.65  ?  785  THR   A CG2  1 
ATOM   1442 H  H    . THR   A 1 93  ? 41.239 10.684  34.759 1.00 72.86  ?  785  THR   A H    1 
ATOM   1443 H  HA   . THR   A 1 93  ? 41.379 7.827   35.627 1.00 77.90  ?  785  THR   A HA   1 
ATOM   1444 H  HB   . THR   A 1 93  ? 39.869 8.004   33.802 1.00 80.06  ?  785  THR   A HB   1 
ATOM   1445 H  HG1  . THR   A 1 93  ? 42.412 7.248   32.935 1.00 89.82  ?  785  THR   A HG1  1 
ATOM   1446 H  HG21 . THR   A 1 93  ? 40.421 8.909   31.583 1.00 78.65  ?  785  THR   A HG21 1 
ATOM   1447 H  HG22 . THR   A 1 93  ? 40.347 10.181  32.776 1.00 78.65  ?  785  THR   A HG22 1 
ATOM   1448 H  HG23 . THR   A 1 93  ? 41.906 9.615   32.199 1.00 78.65  ?  785  THR   A HG23 1 
ATOM   1449 N  N    . VAL   A 1 94  ? 43.840 8.029   35.497 1.00 66.55  ?  786  VAL   A N    1 
ATOM   1450 C  CA   . VAL   A 1 94  ? 45.297 8.147   35.477 1.00 72.00  ?  786  VAL   A CA   1 
ATOM   1451 C  C    . VAL   A 1 94  ? 45.839 7.802   34.085 1.00 71.57  ?  786  VAL   A C    1 
ATOM   1452 O  O    . VAL   A 1 94  ? 45.241 7.029   33.322 1.00 69.60  ?  786  VAL   A O    1 
ATOM   1453 C  CB   . VAL   A 1 94  ? 45.913 7.257   36.577 1.00 68.44  ?  786  VAL   A CB   1 
ATOM   1454 C  CG1  . VAL   A 1 94  ? 47.434 7.346   36.706 1.00 59.39  ?  786  VAL   A CG1  1 
ATOM   1455 C  CG2  . VAL   A 1 94  ? 45.285 7.535   37.942 1.00 62.05  ?  786  VAL   A CG2  1 
ATOM   1456 H  H    . VAL   A 1 94  ? 43.435 7.261   36.010 1.00 68.55  ?  786  VAL   A H    1 
ATOM   1457 H  HA   . VAL   A 1 94  ? 45.547 9.187   35.701 1.00 74.00  ?  786  VAL   A HA   1 
ATOM   1458 H  HB   . VAL   A 1 94  ? 45.691 6.220   36.331 1.00 70.44  ?  786  VAL   A HB   1 
ATOM   1459 H  HG11 . VAL   A 1 94  ? 47.796 6.698   37.505 1.00 61.39  ?  786  VAL   A HG11 1 
ATOM   1460 H  HG12 . VAL   A 1 94  ? 47.952 7.028   35.801 1.00 61.39  ?  786  VAL   A HG12 1 
ATOM   1461 H  HG13 . VAL   A 1 94  ? 47.758 8.359   36.943 1.00 61.39  ?  786  VAL   A HG13 1 
ATOM   1462 H  HG21 . VAL   A 1 94  ? 45.760 6.939   38.721 1.00 64.05  ?  786  VAL   A HG21 1 
ATOM   1463 H  HG22 . VAL   A 1 94  ? 45.392 8.584   38.218 1.00 64.05  ?  786  VAL   A HG22 1 
ATOM   1464 H  HG23 . VAL   A 1 94  ? 44.223 7.288   37.972 1.00 64.05  ?  786  VAL   A HG23 1 
ATOM   1465 N  N    . GLN   A 1 95  ? 46.957 8.427   33.752 1.00 66.40  ?  787  GLN   A N    1 
ATOM   1466 C  CA   . GLN   A 1 95  ? 47.590 8.222   32.460 1.00 59.26  ?  787  GLN   A CA   1 
ATOM   1467 C  C    . GLN   A 1 95  ? 49.013 7.764   32.718 1.00 51.05  ?  787  GLN   A C    1 
ATOM   1468 O  O    . GLN   A 1 95  ? 49.725 8.415   33.493 1.00 37.87  ?  787  GLN   A O    1 
ATOM   1469 C  CB   . GLN   A 1 95  ? 47.524 9.498   31.622 1.00 58.65  ?  787  GLN   A CB   1 
ATOM   1470 C  CG   . GLN   A 1 95  ? 46.127 10.130  31.576 1.00 51.49  ?  787  GLN   A CG   1 
ATOM   1471 C  CD   . GLN   A 1 95  ? 46.070 11.361  30.710 1.00 59.84  ?  787  GLN   A CD   1 
ATOM   1472 O  OE1  . GLN   A 1 95  ? 46.297 11.309  29.505 1.00 69.03  ?  787  GLN   A OE1  1 
ATOM   1473 N  NE2  . GLN   A 1 95  ? 45.763 12.488  31.311 1.00 65.21  ?  787  GLN   A NE2  1 
ATOM   1474 H  H    . GLN   A 1 95  ? 47.400 9.056   34.414 1.00 68.40  ?  787  GLN   A H    1 
ATOM   1475 H  HA   . GLN   A 1 95  ? 47.089 7.445   31.889 1.00 61.26  ?  787  GLN   A HA   1 
ATOM   1476 H  HB2  . GLN   A 1 95  ? 48.239 10.229  31.995 1.00 60.65  ?  787  GLN   A HB2  1 
ATOM   1477 H  HB3  . GLN   A 1 95  ? 47.850 9.266   30.607 1.00 60.65  ?  787  GLN   A HB3  1 
ATOM   1478 H  HG2  . GLN   A 1 95  ? 45.406 9.411   31.190 1.00 53.49  ?  787  GLN   A HG2  1 
ATOM   1479 H  HG3  . GLN   A 1 95  ? 45.792 10.391  32.580 1.00 53.49  ?  787  GLN   A HG3  1 
ATOM   1480 H  HE21 . GLN   A 1 95  ? 45.557 12.495  32.311 1.00 67.21  ?  787  GLN   A HE21 1 
ATOM   1481 H  HE22 . GLN   A 1 95  ? 45.723 13.352  30.781 1.00 67.21  ?  787  GLN   A HE22 1 
ATOM   1482 N  N    . LEU   A 1 96  ? 49.415 6.656   32.098 1.00 46.50  ?  788  LEU   A N    1 
ATOM   1483 C  CA   . LEU   A 1 96  ? 50.833 6.288   32.057 1.00 48.99  ?  788  LEU   A CA   1 
ATOM   1484 C  C    . LEU   A 1 96  ? 51.435 6.829   30.765 1.00 43.23  ?  788  LEU   A C    1 
ATOM   1485 O  O    . LEU   A 1 96  ? 50.868 6.626   29.687 1.00 41.93  ?  788  LEU   A O    1 
ATOM   1486 C  CB   . LEU   A 1 96  ? 51.030 4.770   32.037 1.00 37.66  ?  788  LEU   A CB   1 
ATOM   1487 C  CG   . LEU   A 1 96  ? 50.444 3.956   33.192 1.00 51.04  ?  788  LEU   A CG   1 
ATOM   1488 C  CD1  . LEU   A 1 96  ? 51.096 2.578   33.240 1.00 42.95  ?  788  LEU   A CD1  1 
ATOM   1489 C  CD2  . LEU   A 1 96  ? 50.548 4.612   34.560 1.00 54.42  ?  788  LEU   A CD2  1 
ATOM   1490 H  H    . LEU   A 1 96  ? 48.768 6.175   31.473 1.00 48.50  ?  788  LEU   A H    1 
ATOM   1491 H  HA   . LEU   A 1 96  ? 51.380 6.696   32.909 1.00 50.99  ?  788  LEU   A HA   1 
ATOM   1492 H  HB2  . LEU   A 1 96  ? 50.637 4.356   31.110 1.00 39.66  ?  788  LEU   A HB2  1 
ATOM   1493 H  HB3  . LEU   A 1 96  ? 52.098 4.571   31.981 1.00 39.66  ?  788  LEU   A HB3  1 
ATOM   1494 H  HG   . LEU   A 1 96  ? 49.380 3.819   32.986 1.00 53.04  ?  788  LEU   A HG   1 
ATOM   1495 H  HD11 . LEU   A 1 96  ? 50.639 1.944   34.000 1.00 44.95  ?  788  LEU   A HD11 1 
ATOM   1496 H  HD12 . LEU   A 1 96  ? 51.006 2.055   32.287 1.00 44.95  ?  788  LEU   A HD12 1 
ATOM   1497 H  HD13 . LEU   A 1 96  ? 52.158 2.643   33.479 1.00 44.95  ?  788  LEU   A HD13 1 
ATOM   1498 H  HD21 . LEU   A 1 96  ? 50.076 3.994   35.325 1.00 56.42  ?  788  LEU   A HD21 1 
ATOM   1499 H  HD22 . LEU   A 1 96  ? 51.590 4.738   34.848 1.00 56.42  ?  788  LEU   A HD22 1 
ATOM   1500 H  HD23 . LEU   A 1 96  ? 50.054 5.583   34.599 1.00 56.42  ?  788  LEU   A HD23 1 
ATOM   1501 N  N    . ILE   A 1 97  ? 52.576 7.496   30.877 1.00 39.57  ?  789  ILE   A N    1 
ATOM   1502 C  CA   . ILE   A 1 97  ? 53.266 8.067   29.723 1.00 40.24  ?  789  ILE   A CA   1 
ATOM   1503 C  C    . ILE   A 1 97  ? 54.496 7.201   29.446 1.00 43.41  ?  789  ILE   A C    1 
ATOM   1504 O  O    . ILE   A 1 97  ? 55.401 7.057   30.282 1.00 32.49  ?  789  ILE   A O    1 
ATOM   1505 C  CB   . ILE   A 1 97  ? 53.672 9.530   30.008 1.00 47.45  ?  789  ILE   A CB   1 
ATOM   1506 C  CG1  . ILE   A 1 97  ? 52.524 10.388  30.553 1.00 53.12  ?  789  ILE   A CG1  1 
ATOM   1507 C  CG2  . ILE   A 1 97  ? 54.336 10.212  28.812 1.00 45.54  ?  789  ILE   A CG2  1 
ATOM   1508 C  CD1  . ILE   A 1 97  ? 51.408 10.645  29.571 1.00 64.41  ?  789  ILE   A CD1  1 
ATOM   1509 H  H    . ILE   A 1 97  ? 53.019 7.621   31.786 1.00 41.57  ?  789  ILE   A H    1 
ATOM   1510 H  HA   . ILE   A 1 97  ? 52.629 8.066   28.837 1.00 42.24  ?  789  ILE   A HA   1 
ATOM   1511 H  HB   . ILE   A 1 97  ? 54.420 9.510   30.803 1.00 49.45  ?  789  ILE   A HB   1 
ATOM   1512 H  HG12 . ILE   A 1 97  ? 52.112 9.948   31.462 1.00 55.12  ?  789  ILE   A HG12 1 
ATOM   1513 H  HG13 . ILE   A 1 97  ? 52.893 11.364  30.854 1.00 55.12  ?  789  ILE   A HG13 1 
ATOM   1514 H  HG21 . ILE   A 1 97  ? 54.589 11.248  29.041 1.00 47.54  ?  789  ILE   A HG21 1 
ATOM   1515 H  HG22 . ILE   A 1 97  ? 55.265 9.717   28.535 1.00 47.54  ?  789  ILE   A HG22 1 
ATOM   1516 H  HG23 . ILE   A 1 97  ? 53.691 10.211  27.934 1.00 47.54  ?  789  ILE   A HG23 1 
ATOM   1517 H  HD11 . ILE   A 1 97  ? 50.544 11.080  30.071 1.00 66.41  ?  789  ILE   A HD11 1 
ATOM   1518 H  HD12 . ILE   A 1 97  ? 51.722 11.349  28.799 1.00 66.41  ?  789  ILE   A HD12 1 
ATOM   1519 H  HD13 . ILE   A 1 97  ? 51.082 9.724   29.094 1.00 66.41  ?  789  ILE   A HD13 1 
ATOM   1520 N  N    . MET   A 1 98  ? 54.502 6.605   28.264 1.00 29.93  ?  790  MET   A N    1 
ATOM   1521 C  CA   . MET   A 1 98  ? 55.512 5.629   27.860 1.00 40.89  ?  790  MET   A CA   1 
ATOM   1522 C  C    . MET   A 1 98  ? 56.155 6.064   26.546 1.00 40.82  ?  790  MET   A C    1 
ATOM   1523 O  O    . MET   A 1 98  ? 55.679 6.972   25.862 1.00 40.01  ?  790  MET   A O    1 
ATOM   1524 C  CB   . MET   A 1 98  ? 54.875 4.248   27.717 1.00 39.48  ?  790  MET   A CB   1 
ATOM   1525 C  CG   . MET   A 1 98  ? 53.985 3.837   28.893 1.00 58.50  ?  790  MET   A CG   1 
ATOM   1526 S  SD   . MET   A 1 98  ? 53.079 2.315   28.610 1.00 51.45  ?  790  MET   A SD   1 
ATOM   1527 C  CE   . MET   A 1 98  ? 51.990 2.799   27.273 1.00 69.82  ?  790  MET   A CE   1 
ATOM   1528 H  H    . MET   A 1 98  ? 53.745 6.778   27.601 1.00 31.93  ?  790  MET   A H    1 
ATOM   1529 H  HA   . MET   A 1 98  ? 56.312 5.558   28.600 1.00 42.89  ?  790  MET   A HA   1 
ATOM   1530 H  HB2  . MET   A 1 98  ? 54.280 4.245   26.805 1.00 41.48  ?  790  MET   A HB2  1 
ATOM   1531 H  HB3  . MET   A 1 98  ? 55.649 3.493   27.570 1.00 41.48  ?  790  MET   A HB3  1 
ATOM   1532 H  HG2  . MET   A 1 98  ? 54.597 3.709   29.785 1.00 60.50  ?  790  MET   A HG2  1 
ATOM   1533 H  HG3  . MET   A 1 98  ? 53.237 4.594   29.128 1.00 60.50  ?  790  MET   A HG3  1 
ATOM   1534 H  HE1  . MET   A 1 98  ? 51.231 2.032   27.124 1.00 71.82  ?  790  MET   A HE1  1 
ATOM   1535 H  HE2  . MET   A 1 98  ? 51.499 3.748   27.492 1.00 71.82  ?  790  MET   A HE2  1 
ATOM   1536 H  HE3  . MET   A 1 98  ? 52.541 2.898   26.339 1.00 71.82  ?  790  MET   A HE3  1 
ATOM   1537 N  N    . GLN   A 1 99  ? 57.234 5.397   26.162 1.00 37.72  ?  791  GLN   A N    1 
ATOM   1538 C  CA   . GLN   A 1 99  ? 57.889 5.693   24.891 1.00 29.90  ?  791  GLN   A CA   1 
ATOM   1539 C  C    . GLN   A 1 99  ? 57.067 5.193   23.707 1.00 37.12  ?  791  GLN   A C    1 
ATOM   1540 O  O    . GLN   A 1 99  ? 56.570 4.060   23.722 1.00 27.07  ?  791  GLN   A O    1 
ATOM   1541 C  CB   . GLN   A 1 99  ? 59.254 5.019   24.899 1.00 31.41  ?  791  GLN   A CB   1 
ATOM   1542 C  CG   . GLN   A 1 99  ? 60.046 5.060   23.586 1.00 51.55  ?  791  GLN   A CG   1 
ATOM   1543 C  CD   . GLN   A 1 99  ? 61.414 4.452   23.760 1.00 61.50  ?  791  GLN   A CD   1 
ATOM   1544 O  OE1  . GLN   A 1 99  ? 61.603 3.496   24.510 1.00 52.73  ?  791  GLN   A OE1  1 
ATOM   1545 N  NE2  . GLN   A 1 99  ? 62.391 5.000   23.075 1.00 38.45  ?  791  GLN   A NE2  1 
ATOM   1546 H  H    . GLN   A 1 99  ? 57.593 4.645   26.729 1.00 39.72  ?  791  GLN   A H    1 
ATOM   1547 H  HA   . GLN   A 1 99  ? 58.036 6.772   24.797 1.00 31.90  ?  791  GLN   A HA   1 
ATOM   1548 H  HB2  . GLN   A 1 99  ? 59.858 5.473   25.687 1.00 33.41  ?  791  GLN   A HB2  1 
ATOM   1549 H  HB3  . GLN   A 1 99  ? 59.130 3.972   25.185 1.00 33.41  ?  791  GLN   A HB3  1 
ATOM   1550 H  HG2  . GLN   A 1 99  ? 59.548 4.479   22.810 1.00 53.55  ?  791  GLN   A HG2  1 
ATOM   1551 H  HG3  . GLN   A 1 99  ? 60.127 6.085   23.225 1.00 53.55  ?  791  GLN   A HG3  1 
ATOM   1552 H  HE21 . GLN   A 1 99  ? 62.209 5.785   22.462 1.00 40.45  ?  791  GLN   A HE21 1 
ATOM   1553 H  HE22 . GLN   A 1 99  ? 63.334 4.648   23.179 1.00 40.45  ?  791  GLN   A HE22 1 
ATOM   1554 N  N    . LEU   A 1 100 ? 56.952 6.021   22.668 1.00 34.52  ?  792  LEU   A N    1 
ATOM   1555 C  CA   . LEU   A 1 100 ? 56.308 5.546   21.448 1.00 38.42  ?  792  LEU   A CA   1 
ATOM   1556 C  C    . LEU   A 1 100 ? 57.214 4.539   20.752 1.00 38.58  ?  792  LEU   A C    1 
ATOM   1557 O  O    . LEU   A 1 100 ? 58.378 4.831   20.477 1.00 38.75  ?  792  LEU   A O    1 
ATOM   1558 C  CB   . LEU   A 1 100 ? 56.021 6.702   20.489 1.00 25.98  ?  792  LEU   A CB   1 
ATOM   1559 C  CG   . LEU   A 1 100 ? 55.165 6.357   19.263 1.00 38.11  ?  792  LEU   A CG   1 
ATOM   1560 C  CD1  . LEU   A 1 100 ? 53.733 6.012   19.628 1.00 33.10  ?  792  LEU   A CD1  1 
ATOM   1561 C  CD2  . LEU   A 1 100 ? 55.159 7.496   18.262 1.00 31.31  ?  792  LEU   A CD2  1 
ATOM   1562 H  H    . LEU   A 1 100 ? 57.404 6.926   22.669 1.00 36.52  ?  792  LEU   A H    1 
ATOM   1563 H  HA   . LEU   A 1 100 ? 55.362 5.078   21.728 1.00 40.42  ?  792  LEU   A HA   1 
ATOM   1564 H  HB2  . LEU   A 1 100 ? 55.520 7.500   21.029 1.00 27.98  ?  792  LEU   A HB2  1 
ATOM   1565 H  HB3  . LEU   A 1 100 ? 56.971 7.128   20.158 1.00 27.98  ?  792  LEU   A HB3  1 
ATOM   1566 H  HG   . LEU   A 1 100 ? 55.596 5.495   18.753 1.00 40.11  ?  792  LEU   A HG   1 
ATOM   1567 H  HD11 . LEU   A 1 100 ? 53.159 5.736   18.744 1.00 35.10  ?  792  LEU   A HD11 1 
ATOM   1568 H  HD12 . LEU   A 1 100 ? 53.665 5.175   20.317 1.00 35.10  ?  792  LEU   A HD12 1 
ATOM   1569 H  HD13 . LEU   A 1 100 ? 53.229 6.855   20.102 1.00 35.10  ?  792  LEU   A HD13 1 
ATOM   1570 H  HD21 . LEU   A 1 100 ? 54.568 7.244   17.381 1.00 33.31  ?  792  LEU   A HD21 1 
ATOM   1571 H  HD22 . LEU   A 1 100 ? 54.743 8.407   18.694 1.00 33.31  ?  792  LEU   A HD22 1 
ATOM   1572 H  HD23 . LEU   A 1 100 ? 56.169 7.720   17.916 1.00 33.31  ?  792  LEU   A HD23 1 
ATOM   1573 N  N    . MET   A 1 101 ? 56.653 3.374   20.469 1.00 30.12  ?  793  MET   A N    1 
ATOM   1574 C  CA   . MET   A 1 101 ? 57.315 2.331   19.702 1.00 33.25  ?  793  MET   A CA   1 
ATOM   1575 C  C    . MET   A 1 101 ? 56.579 2.252   18.372 1.00 28.34  ?  793  MET   A C    1 
ATOM   1576 O  O    . MET   A 1 101 ? 55.608 1.500   18.242 1.00 37.87  ?  793  MET   A O    1 
ATOM   1577 C  CB   . MET   A 1 101 ? 57.198 1.002   20.451 1.00 29.19  ?  793  MET   A CB   1 
ATOM   1578 C  CG   . MET   A 1 101 ? 57.839 1.026   21.835 1.00 30.61  ?  793  MET   A CG   1 
ATOM   1579 S  SD   . MET   A 1 101 ? 59.628 1.211   21.787 1.00 36.44  ?  793  MET   A SD   1 
ATOM   1580 C  CE   . MET   A 1 101 ? 60.030 -0.500  21.483 1.00 31.09  ?  793  MET   A CE   1 
ATOM   1581 H  H    . MET   A 1 101 ? 55.666 3.223   20.682 1.00 32.12  ?  793  MET   A H    1 
ATOM   1582 H  HA   . MET   A 1 101 ? 58.374 2.535   19.541 1.00 35.25  ?  793  MET   A HA   1 
ATOM   1583 H  HB2  . MET   A 1 101 ? 56.148 0.734   20.581 1.00 31.19  ?  793  MET   A HB2  1 
ATOM   1584 H  HB3  . MET   A 1 101 ? 57.632 0.204   19.849 1.00 31.19  ?  793  MET   A HB3  1 
ATOM   1585 H  HG2  . MET   A 1 101 ? 57.434 1.841   22.433 1.00 32.61  ?  793  MET   A HG2  1 
ATOM   1586 H  HG3  . MET   A 1 101 ? 57.595 0.119   22.385 1.00 32.61  ?  793  MET   A HG3  1 
ATOM   1587 H  HE1  . MET   A 1 101 ? 61.098 -0.620  21.319 1.00 33.09  ?  793  MET   A HE1  1 
ATOM   1588 H  HE2  . MET   A 1 101 ? 59.733 -1.116  22.329 1.00 33.09  ?  793  MET   A HE2  1 
ATOM   1589 H  HE3  . MET   A 1 101 ? 59.520 -0.860  20.595 1.00 33.09  ?  793  MET   A HE3  1 
ATOM   1590 N  N    . PRO   A 1 102 ? 56.941 3.072   17.381 1.00 31.64  ?  794  PRO   A N    1 
ATOM   1591 C  CA   . PRO   A 1 102 ? 56.030 3.372   16.285 1.00 31.62  ?  794  PRO   A CA   1 
ATOM   1592 C  C    . PRO   A 1 102 ? 55.704 2.249   15.317 1.00 41.94  ?  794  PRO   A C    1 
ATOM   1593 O  O    . PRO   A 1 102 ? 54.698 2.328   14.612 1.00 44.18  ?  794  PRO   A O    1 
ATOM   1594 C  CB   . PRO   A 1 102 ? 56.656 4.564   15.579 1.00 34.98  ?  794  PRO   A CB   1 
ATOM   1595 C  CG   . PRO   A 1 102 ? 58.137 4.523   15.943 1.00 26.14  ?  794  PRO   A CG   1 
ATOM   1596 C  CD   . PRO   A 1 102 ? 58.201 3.816   17.300 1.00 20.72  ?  794  PRO   A CD   1 
ATOM   1597 H  HA   . PRO   A 1 102 ? 55.075 3.691   16.710 1.00 33.62  ?  794  PRO   A HA   1 
ATOM   1598 H  HB2  . PRO   A 1 102 ? 56.493 4.576   14.499 1.00 36.98  ?  794  PRO   A HB2  1 
ATOM   1599 H  HB3  . PRO   A 1 102 ? 56.216 5.481   15.975 1.00 36.98  ?  794  PRO   A HB3  1 
ATOM   1600 H  HG2  . PRO   A 1 102 ? 58.672 3.926   15.201 1.00 28.14  ?  794  PRO   A HG2  1 
ATOM   1601 H  HG3  . PRO   A 1 102 ? 58.598 5.511   15.958 1.00 28.14  ?  794  PRO   A HG3  1 
ATOM   1602 H  HD2  . PRO   A 1 102 ? 59.075 3.172   17.373 1.00 22.72  ?  794  PRO   A HD2  1 
ATOM   1603 H  HD3  . PRO   A 1 102 ? 58.254 4.570   18.079 1.00 22.72  ?  794  PRO   A HD3  1 
ATOM   1604 N  N    . PHE   A 1 103 ? 56.512 1.196   15.300 1.00 39.52  ?  795  PHE   A N    1 
ATOM   1605 C  CA   . PHE   A 1 103 ? 56.237 0.092   14.388 1.00 31.74  ?  795  PHE   A CA   1 
ATOM   1606 C  C    . PHE   A 1 103 ? 55.370 -0.991  15.024 1.00 41.43  ?  795  PHE   A C    1 
ATOM   1607 O  O    . PHE   A 1 103 ? 55.029 -1.972  14.354 1.00 39.21  ?  795  PHE   A O    1 
ATOM   1608 C  CB   . PHE   A 1 103 ? 57.543 -0.504  13.895 1.00 30.76  ?  795  PHE   A CB   1 
ATOM   1609 C  CG   . PHE   A 1 103 ? 58.353 0.427   13.003 1.00 36.44  ?  795  PHE   A CG   1 
ATOM   1610 C  CD1  . PHE   A 1 103 ? 59.232 1.366   13.579 1.00 40.60  ?  795  PHE   A CD1  1 
ATOM   1611 C  CD2  . PHE   A 1 103 ? 58.224 0.354   11.601 1.00 31.97  ?  795  PHE   A CD2  1 
ATOM   1612 C  CE1  . PHE   A 1 103 ? 59.981 2.230   12.758 1.00 35.63  ?  795  PHE   A CE1  1 
ATOM   1613 C  CE2  . PHE   A 1 103 ? 58.976 1.217   10.779 1.00 36.86  ?  795  PHE   A CE2  1 
ATOM   1614 C  CZ   . PHE   A 1 103 ? 59.855 2.154   11.357 1.00 43.14  ?  795  PHE   A CZ   1 
ATOM   1615 H  H    . PHE   A 1 103 ? 57.307 1.130   15.922 1.00 41.52  ?  795  PHE   A H    1 
ATOM   1616 H  HA   . PHE   A 1 103 ? 55.699 0.428   13.499 1.00 33.74  ?  795  PHE   A HA   1 
ATOM   1617 H  HB2  . PHE   A 1 103 ? 58.160 -0.766  14.749 1.00 32.76  ?  795  PHE   A HB2  1 
ATOM   1618 H  HB3  . PHE   A 1 103 ? 57.370 -1.434  13.349 1.00 32.76  ?  795  PHE   A HB3  1 
ATOM   1619 H  HD1  . PHE   A 1 103 ? 59.327 1.425   14.652 1.00 42.60  ?  795  PHE   A HD1  1 
ATOM   1620 H  HD2  . PHE   A 1 103 ? 57.548 -0.363  11.156 1.00 33.97  ?  795  PHE   A HD2  1 
ATOM   1621 H  HE1  . PHE   A 1 103 ? 60.653 2.951   13.203 1.00 37.63  ?  795  PHE   A HE1  1 
ATOM   1622 H  HE2  . PHE   A 1 103 ? 58.878 1.160   9.705  1.00 38.86  ?  795  PHE   A HE2  1 
ATOM   1623 H  HZ   . PHE   A 1 103 ? 60.431 2.817   10.726 1.00 45.14  ?  795  PHE   A HZ   1 
ATOM   1624 N  N    . GLY   A 1 104 ? 55.000 -0.831  16.295 1.00 39.37  ?  796  GLY   A N    1 
ATOM   1625 C  CA   . GLY   A 1 104 ? 54.001 -1.715  16.884 1.00 30.61  ?  796  GLY   A CA   1 
ATOM   1626 C  C    . GLY   A 1 104 ? 54.611 -2.942  17.536 1.00 37.23  ?  796  GLY   A C    1 
ATOM   1627 O  O    . GLY   A 1 104 ? 55.805 -2.960  17.847 1.00 35.96  ?  796  GLY   A O    1 
ATOM   1628 H  H    . GLY   A 1 104 ? 55.324 -0.032  16.829 1.00 41.37  ?  796  GLY   A H    1 
ATOM   1629 H  HA2  . GLY   A 1 104 ? 53.486 -1.153  17.664 1.00 32.61  ?  796  GLY   A HA2  1 
ATOM   1630 H  HA3  . GLY   A 1 104 ? 53.234 -1.988  16.160 1.00 32.61  ?  796  GLY   A HA3  1 
ATOM   1631 N  N    . SER   A 1 105 ? 53.788 -3.971  17.736 1.00 27.75  ?  797  SER   A N    1 
ATOM   1632 C  CA   . SER   A 1 105 ? 54.288 -5.237  18.263 1.00 39.98  ?  797  SER   A CA   1 
ATOM   1633 C  C    . SER   A 1 105 ? 55.074 -6.012  17.215 1.00 44.13  ?  797  SER   A C    1 
ATOM   1634 O  O    . SER   A 1 105 ? 54.800 -5.938  16.008 1.00 46.92  ?  797  SER   A O    1 
ATOM   1635 C  CB   . SER   A 1 105 ? 53.172 -6.123  18.826 1.00 27.01  ?  797  SER   A CB   1 
ATOM   1636 O  OG   . SER   A 1 105 ? 52.371 -6.770  17.843 1.00 51.37  ?  797  SER   A OG   1 
ATOM   1637 H  H    . SER   A 1 105 ? 52.824 -3.916  17.397 1.00 29.75  ?  797  SER   A H    1 
ATOM   1638 H  HA   . SER   A 1 105 ? 54.953 -5.009  19.089 1.00 41.98  ?  797  SER   A HA   1 
ATOM   1639 H  HB2  . SER   A 1 105 ? 53.627 -6.905  19.436 1.00 29.01  ?  797  SER   A HB2  1 
ATOM   1640 H  HB3  . SER   A 1 105 ? 52.534 -5.554  19.505 1.00 29.01  ?  797  SER   A HB3  1 
ATOM   1641 H  HG   . SER   A 1 105 ? 51.775 -6.131  17.463 1.00 53.37  ?  797  SER   A HG   1 
ATOM   1642 N  N    . LEU   A 1 106 ? 56.032 -6.785  17.708 1.00 34.89  ?  798  LEU   A N    1 
ATOM   1643 C  CA   . LEU   A 1 106 ? 56.868 -7.615  16.866 1.00 37.49  ?  798  LEU   A CA   1 
ATOM   1644 C  C    . LEU   A 1 106 ? 56.069 -8.731  16.203 1.00 41.01  ?  798  LEU   A C    1 
ATOM   1645 O  O    . LEU   A 1 106 ? 56.307 -9.042  15.034 1.00 33.81  ?  798  LEU   A O    1 
ATOM   1646 C  CB   . LEU   A 1 106 ? 58.062 -8.141  17.676 1.00 25.69  ?  798  LEU   A CB   1 
ATOM   1647 C  CG   . LEU   A 1 106 ? 59.087 -8.989  16.918 1.00 30.42  ?  798  LEU   A CG   1 
ATOM   1648 C  CD1  . LEU   A 1 106 ? 59.669 -8.273  15.707 1.00 28.64  ?  798  LEU   A CD1  1 
ATOM   1649 C  CD2  . LEU   A 1 106 ? 60.208 -9.444  17.839 1.00 17.87  ?  798  LEU   A CD2  1 
ATOM   1650 H  H    . LEU   A 1 106 ? 56.208 -6.783  18.715 1.00 36.89  ?  798  LEU   A H    1 
ATOM   1651 H  HA   . LEU   A 1 106 ? 57.252 -6.977  16.070 1.00 39.49  ?  798  LEU   A HA   1 
ATOM   1652 H  HB2  . LEU   A 1 106 ? 58.579 -7.289  18.122 1.00 27.69  ?  798  LEU   A HB2  1 
ATOM   1653 H  HB3  . LEU   A 1 106 ? 57.681 -8.725  18.516 1.00 27.69  ?  798  LEU   A HB3  1 
ATOM   1654 H  HG   . LEU   A 1 106 ? 58.586 -9.886  16.556 1.00 32.42  ?  798  LEU   A HG   1 
ATOM   1655 H  HD11 . LEU   A 1 106 ? 60.406 -8.900  15.213 1.00 30.64  ?  798  LEU   A HD11 1 
ATOM   1656 H  HD12 . LEU   A 1 106 ? 58.915 -8.044  14.955 1.00 30.64  ?  798  LEU   A HD12 1 
ATOM   1657 H  HD13 . LEU   A 1 106 ? 60.166 -7.343  15.982 1.00 30.64  ?  798  LEU   A HD13 1 
ATOM   1658 H  HD21 . LEU   A 1 106 ? 60.906 -10.103 17.320 1.00 19.87  ?  798  LEU   A HD21 1 
ATOM   1659 H  HD22 . LEU   A 1 106 ? 60.781 -8.599  18.223 1.00 19.87  ?  798  LEU   A HD22 1 
ATOM   1660 H  HD23 . LEU   A 1 106 ? 59.818 -9.991  18.699 1.00 19.87  ?  798  LEU   A HD23 1 
ATOM   1661 N  N    . LEU   A 1 107 ? 55.070 -9.257  16.913 1.00 33.24  ?  799  LEU   A N    1 
ATOM   1662 C  CA   . LEU   A 1 107 ? 54.130 -10.215 16.327 1.00 45.41  ?  799  LEU   A CA   1 
ATOM   1663 C  C    . LEU   A 1 107 ? 53.438 -9.720  15.066 1.00 51.88  ?  799  LEU   A C    1 
ATOM   1664 O  O    . LEU   A 1 107 ? 53.445 -10.384 14.025 1.00 49.38  ?  799  LEU   A O    1 
ATOM   1665 C  CB   . LEU   A 1 107 ? 53.091 -10.662 17.351 1.00 32.03  ?  799  LEU   A CB   1 
ATOM   1666 C  CG   . LEU   A 1 107 ? 52.018 -11.632 16.853 1.00 43.60  ?  799  LEU   A CG   1 
ATOM   1667 C  CD1  . LEU   A 1 107 ? 52.629 -12.929 16.336 1.00 40.10  ?  799  LEU   A CD1  1 
ATOM   1668 C  CD2  . LEU   A 1 107 ? 50.987 -11.903 17.937 1.00 24.15  ?  799  LEU   A CD2  1 
ATOM   1669 H  H    . LEU   A 1 107 ? 54.953 -8.968  17.876 1.00 35.24  ?  799  LEU   A H    1 
ATOM   1670 H  HA   . LEU   A 1 107 ? 54.721 -11.088 16.051 1.00 47.41  ?  799  LEU   A HA   1 
ATOM   1671 H  HB2  . LEU   A 1 107 ? 53.606 -11.132 18.184 1.00 34.03  ?  799  LEU   A HB2  1 
ATOM   1672 H  HB3  . LEU   A 1 107 ? 52.602 -9.778  17.765 1.00 34.03  ?  799  LEU   A HB3  1 
ATOM   1673 H  HG   . LEU   A 1 107 ? 51.457 -11.176 16.036 1.00 45.60  ?  799  LEU   A HG   1 
ATOM   1674 H  HD11 . LEU   A 1 107 ? 51.855 -13.646 16.064 1.00 42.10  ?  799  LEU   A HD11 1 
ATOM   1675 H  HD12 . LEU   A 1 107 ? 53.228 -12.759 15.442 1.00 42.10  ?  799  LEU   A HD12 1 
ATOM   1676 H  HD13 . LEU   A 1 107 ? 53.265 -13.405 17.084 1.00 42.10  ?  799  LEU   A HD13 1 
ATOM   1677 H  HD21 . LEU   A 1 107 ? 50.173 -12.525 17.563 1.00 26.15  ?  799  LEU   A HD21 1 
ATOM   1678 H  HD22 . LEU   A 1 107 ? 51.431 -12.418 18.788 1.00 26.15  ?  799  LEU   A HD22 1 
ATOM   1679 H  HD23 . LEU   A 1 107 ? 50.544 -10.977 18.306 1.00 26.15  ?  799  LEU   A HD23 1 
ATOM   1680 N  N    . ASP   A 1 108 ? 52.849 -8.535  15.164 1.00 44.63  ?  800  ASP   A N    1 
ATOM   1681 C  CA   . ASP   A 1 108 ? 52.169 -7.990  13.996 1.00 44.10  ?  800  ASP   A CA   1 
ATOM   1682 C  C    . ASP   A 1 108 ? 53.148 -7.604  12.899 1.00 44.11  ?  800  ASP   A C    1 
ATOM   1683 O  O    . ASP   A 1 108 ? 52.845 -7.730  11.714 1.00 46.54  ?  800  ASP   A O    1 
ATOM   1684 C  CB   . ASP   A 1 108 ? 51.322 -6.773  14.357 1.00 46.56  ?  800  ASP   A CB   1 
ATOM   1685 C  CG   . ASP   A 1 108 ? 50.184 -7.056  15.312 1.00 52.47  ?  800  ASP   A CG   1 
ATOM   1686 O  OD1  . ASP   A 1 108 ? 49.663 -8.191  15.315 1.00 43.20  ?  800  ASP   A OD1  1 
ATOM   1687 O  OD2  . ASP   A 1 108 ? 49.797 -6.143  16.072 1.00 58.56  -1 800  ASP   A OD2  1 
ATOM   1688 H  H    . ASP   A 1 108 ? 52.854 -8.024  16.041 1.00 46.63  ?  800  ASP   A H    1 
ATOM   1689 H  HA   . ASP   A 1 108 ? 51.508 -8.752  13.576 1.00 46.10  ?  800  ASP   A HA   1 
ATOM   1690 H  HB2  . ASP   A 1 108 ? 51.953 -6.023  14.823 1.00 48.56  ?  800  ASP   A HB2  1 
ATOM   1691 H  HB3  . ASP   A 1 108 ? 50.900 -6.316  13.460 1.00 48.56  ?  800  ASP   A HB3  1 
ATOM   1692 N  N    . TYR   A 1 109 ? 54.349 -7.207  13.301 1.00 41.88  ?  801  TYR   A N    1 
ATOM   1693 C  CA   . TYR   A 1 109 ? 55.390 -6.868  12.350 1.00 37.28  ?  801  TYR   A CA   1 
ATOM   1694 C  C    . TYR   A 1 109 ? 55.842 -8.063  11.512 1.00 43.70  ?  801  TYR   A C    1 
ATOM   1695 O  O    . TYR   A 1 109 ? 55.950 -7.957  10.288 1.00 41.60  ?  801  TYR   A O    1 
ATOM   1696 C  CB   . TYR   A 1 109 ? 56.570 -6.232  13.066 1.00 35.21  ?  801  TYR   A CB   1 
ATOM   1697 C  CG   . TYR   A 1 109 ? 57.568 -5.581  12.130 1.00 44.81  ?  801  TYR   A CG   1 
ATOM   1698 C  CD1  . TYR   A 1 109 ? 57.399 -4.236  11.751 1.00 24.87  ?  801  TYR   A CD1  1 
ATOM   1699 C  CD2  . TYR   A 1 109 ? 58.659 -6.324  11.627 1.00 32.81  ?  801  TYR   A CD2  1 
ATOM   1700 C  CE1  . TYR   A 1 109 ? 58.310 -3.638  10.865 1.00 44.25  ?  801  TYR   A CE1  1 
ATOM   1701 C  CE2  . TYR   A 1 109 ? 59.567 -5.722  10.741 1.00 31.67  ?  801  TYR   A CE2  1 
ATOM   1702 C  CZ   . TYR   A 1 109 ? 59.390 -4.383  10.355 1.00 29.48  ?  801  TYR   A CZ   1 
ATOM   1703 O  OH   . TYR   A 1 109 ? 60.260 -3.807  9.485  1.00 53.07  ?  801  TYR   A OH   1 
ATOM   1704 H  H    . TYR   A 1 109 ? 54.534 -7.127  14.294 1.00 43.88  ?  801  TYR   A H    1 
ATOM   1705 H  HA   . TYR   A 1 109 ? 54.973 -6.121  11.671 1.00 39.28  ?  801  TYR   A HA   1 
ATOM   1706 H  HB2  . TYR   A 1 109 ? 56.217 -5.467  13.758 1.00 37.21  ?  801  TYR   A HB2  1 
ATOM   1707 H  HB3  . TYR   A 1 109 ? 57.095 -6.966  13.677 1.00 37.21  ?  801  TYR   A HB3  1 
ATOM   1708 H  HD1  . TYR   A 1 109 ? 56.566 -3.665  12.134 1.00 26.87  ?  801  TYR   A HD1  1 
ATOM   1709 H  HD2  . TYR   A 1 109 ? 58.792 -7.356  11.917 1.00 34.81  ?  801  TYR   A HD2  1 
ATOM   1710 H  HE1  . TYR   A 1 109 ? 58.174 -2.609  10.568 1.00 46.25  ?  801  TYR   A HE1  1 
ATOM   1711 H  HE2  . TYR   A 1 109 ? 60.395 -6.291  10.349 1.00 33.67  ?  801  TYR   A HE2  1 
ATOM   1712 H  HH   . TYR   A 1 109 ? 60.022 -2.921  9.262  1.00 55.07  ?  801  TYR   A HH   1 
ATOM   1713 N  N    . VAL   A 1 110 ? 56.058 -9.213  12.154 1.00 35.36  ?  802  VAL   A N    1 
ATOM   1714 C  CA   . VAL   A 1 110 ? 56.454 -10.394 11.399 1.00 37.71  ?  802  VAL   A CA   1 
ATOM   1715 C  C    . VAL   A 1 110 ? 55.345 -10.926 10.498 1.00 51.69  ?  802  VAL   A C    1 
ATOM   1716 O  O    . VAL   A 1 110 ? 55.619 -11.435 9.412  1.00 53.39  ?  802  VAL   A O    1 
ATOM   1717 C  CB   . VAL   A 1 110 ? 57.050 -11.508 12.275 1.00 24.63  ?  802  VAL   A CB   1 
ATOM   1718 C  CG1  . VAL   A 1 110 ? 58.334 -11.071 12.962 1.00 24.73  ?  802  VAL   A CG1  1 
ATOM   1719 C  CG2  . VAL   A 1 110 ? 56.104 -12.127 13.284 1.00 26.85  ?  802  VAL   A CG2  1 
ATOM   1720 H  H    . VAL   A 1 110 ? 55.984 -9.260  13.168 1.00 37.36  ?  802  VAL   A H    1 
ATOM   1721 H  HA   . VAL   A 1 110 ? 57.246 -10.092 10.720 1.00 39.71  ?  802  VAL   A HA   1 
ATOM   1722 H  HB   . VAL   A 1 110 ? 57.338 -12.308 11.591 1.00 26.63  ?  802  VAL   A HB   1 
ATOM   1723 H  HG11 . VAL   A 1 110 ? 58.849 -11.913 13.425 1.00 26.73  ?  802  VAL   A HG11 1 
ATOM   1724 H  HG12 . VAL   A 1 110 ? 59.012 -10.619 12.246 1.00 26.73  ?  802  VAL   A HG12 1 
ATOM   1725 H  HG13 . VAL   A 1 110 ? 58.151 -10.329 13.738 1.00 26.73  ?  802  VAL   A HG13 1 
ATOM   1726 H  HG21 . VAL   A 1 110 ? 56.551 -13.001 13.758 1.00 28.85  ?  802  VAL   A HG21 1 
ATOM   1727 H  HG22 . VAL   A 1 110 ? 55.865 -11.422 14.076 1.00 28.85  ?  802  VAL   A HG22 1 
ATOM   1728 H  HG23 . VAL   A 1 110 ? 55.164 -12.447 12.839 1.00 28.85  ?  802  VAL   A HG23 1 
ATOM   1729 N  N    . ARG   A 1 111 ? 54.097 -10.755 10.926 1.00 51.25  ?  803  ARG   A N    1 
ATOM   1730 C  CA   . ARG   A 1 111 ? 52.970 -11.113 10.073 1.00 45.55  ?  803  ARG   A CA   1 
ATOM   1731 C  C    . ARG   A 1 111 ? 52.844 -10.204 8.856  1.00 49.84  ?  803  ARG   A C    1 
ATOM   1732 O  O    . ARG   A 1 111 ? 52.625 -10.669 7.735  1.00 48.00  ?  803  ARG   A O    1 
ATOM   1733 C  CB   . ARG   A 1 111 ? 51.666 -11.084 10.852 1.00 33.44  ?  803  ARG   A CB   1 
ATOM   1734 C  CG   . ARG   A 1 111 ? 51.579 -12.184 11.897 1.00 24.92  ?  803  ARG   A CG   1 
ATOM   1735 C  CD   . ARG   A 1 111 ? 50.385 -12.021 12.821 1.00 32.16  ?  803  ARG   A CD   1 
ATOM   1736 N  NE   . ARG   A 1 111 ? 50.206 -13.217 13.656 1.00 41.14  ?  803  ARG   A NE   1 
ATOM   1737 C  CZ   . ARG   A 1 111 ? 49.288 -13.320 14.631 1.00 45.68  ?  803  ARG   A CZ   1 
ATOM   1738 N  NH1  . ARG   A 1 111 ? 48.457 -12.304 14.893 1.00 50.23  ?  803  ARG   A NH1  1 
ATOM   1739 N  NH2  . ARG   A 1 111 ? 49.206 -14.448 15.342 1.00 43.96  1  803  ARG   A NH2  1 
ATOM   1740 H  H    . ARG   A 1 111 ? 53.941 -10.328 11.832 1.00 53.25  ?  803  ARG   A H    1 
ATOM   1741 H  HA   . ARG   A 1 111 ? 53.116 -12.132 9.716  1.00 47.55  ?  803  ARG   A HA   1 
ATOM   1742 H  HB2  . ARG   A 1 111 ? 51.550 -10.112 11.336 1.00 35.44  ?  803  ARG   A HB2  1 
ATOM   1743 H  HB3  . ARG   A 1 111 ? 50.817 -11.184 10.173 1.00 35.44  ?  803  ARG   A HB3  1 
ATOM   1744 H  HG2  . ARG   A 1 111 ? 51.551 -13.158 11.405 1.00 26.92  ?  803  ARG   A HG2  1 
ATOM   1745 H  HG3  . ARG   A 1 111 ? 52.482 -12.175 12.503 1.00 26.92  ?  803  ARG   A HG3  1 
ATOM   1746 H  HD2  . ARG   A 1 111 ? 50.533 -11.153 13.464 1.00 34.16  ?  803  ARG   A HD2  1 
ATOM   1747 H  HD3  . ARG   A 1 111 ? 49.472 -11.861 12.247 1.00 34.16  ?  803  ARG   A HD3  1 
ATOM   1748 H  HE   . ARG   A 1 111 ? 50.820 -14.006 13.478 1.00 43.14  ?  803  ARG   A HE   1 
ATOM   1749 H  HH11 . ARG   A 1 111 ? 48.515 -11.442 14.355 1.00 52.23  ?  803  ARG   A HH11 1 
ATOM   1750 H  HH12 . ARG   A 1 111 ? 47.770 -12.387 15.628 1.00 52.23  ?  803  ARG   A HH12 1 
ATOM   1751 H  HH21 . ARG   A 1 111 ? 49.839 -15.215 15.146 1.00 45.96  ?  803  ARG   A HH21 1 
ATOM   1752 H  HH22 . ARG   A 1 111 ? 48.524 -14.538 16.080 1.00 45.96  ?  803  ARG   A HH22 1 
ATOM   1753 N  N    . GLU   A 1 112 ? 53.012 -8.909  9.086  1.00 41.50  ?  804  GLU   A N    1 
ATOM   1754 C  CA   . GLU   A 1 112 ? 52.862 -7.936  8.018  1.00 45.35  ?  804  GLU   A CA   1 
ATOM   1755 C  C    . GLU   A 1 112 ? 54.034 -7.921  7.037  1.00 47.89  ?  804  GLU   A C    1 
ATOM   1756 O  O    . GLU   A 1 112 ? 53.836 -7.735  5.836  1.00 50.03  ?  804  GLU   A O    1 
ATOM   1757 C  CB   . GLU   A 1 112 ? 52.631 -6.560  8.646  1.00 45.85  ?  804  GLU   A CB   1 
ATOM   1758 C  CG   . GLU   A 1 112 ? 52.553 -5.370  7.682  1.00 72.08  ?  804  GLU   A CG   1 
ATOM   1759 C  CD   . GLU   A 1 112 ? 52.069 -4.141  8.421  1.00 90.00  ?  804  GLU   A CD   1 
ATOM   1760 O  OE1  . GLU   A 1 112 ? 51.111 -3.494  7.949  1.00 101.25 ?  804  GLU   A OE1  1 
ATOM   1761 O  OE2  . GLU   A 1 112 ? 52.642 -3.806  9.480  1.00 104.15 -1 804  GLU   A OE2  1 
ATOM   1762 H  H    . GLU   A 1 112 ? 53.167 -8.573  10.033 1.00 43.50  ?  804  GLU   A H    1 
ATOM   1763 H  HA   . GLU   A 1 112 ? 51.967 -8.180  7.440  1.00 47.35  ?  804  GLU   A HA   1 
ATOM   1764 H  HB2  . GLU   A 1 112 ? 51.709 -6.608  9.229  1.00 47.85  ?  804  GLU   A HB2  1 
ATOM   1765 H  HB3  . GLU   A 1 112 ? 53.422 -6.366  9.372  1.00 47.85  ?  804  GLU   A HB3  1 
ATOM   1766 H  HG2  . GLU   A 1 112 ? 53.527 -5.164  7.237  1.00 74.08  ?  804  GLU   A HG2  1 
ATOM   1767 H  HG3  . GLU   A 1 112 ? 51.867 -5.590  6.862  1.00 74.08  ?  804  GLU   A HG3  1 
ATOM   1768 N  N    . HIS   A 1 113 ? 55.246 -8.126  7.542  1.00 50.92  ?  805  HIS   A N    1 
ATOM   1769 C  CA   . HIS   A 1 113 ? 56.439 -7.875  6.734  1.00 43.27  ?  805  HIS   A CA   1 
ATOM   1770 C  C    . HIS   A 1 113 ? 57.180 -9.144  6.341  1.00 46.12  ?  805  HIS   A C    1 
ATOM   1771 O  O    . HIS   A 1 113 ? 58.307 -9.058  5.854  1.00 58.10  ?  805  HIS   A O    1 
ATOM   1772 C  CB   . HIS   A 1 113 ? 57.376 -6.901  7.435  1.00 51.66  ?  805  HIS   A CB   1 
ATOM   1773 C  CG   . HIS   A 1 113 ? 56.824 -5.514  7.616  1.00 62.69  ?  805  HIS   A CG   1 
ATOM   1774 N  ND1  . HIS   A 1 113 ? 57.069 -4.466  6.706  1.00 62.45  ?  805  HIS   A ND1  1 
ATOM   1775 C  CD2  . HIS   A 1 113 ? 56.020 -5.011  8.646  1.00 61.31  ?  805  HIS   A CD2  1 
ATOM   1776 C  CE1  . HIS   A 1 113 ? 56.440 -3.432  7.205  1.00 63.83  ?  805  HIS   A CE1  1 
ATOM   1777 N  NE2  . HIS   A 1 113 ? 55.810 -3.677  8.329  1.00 54.48  ?  805  HIS   A NE2  1 
ATOM   1778 H  H    . HIS   A 1 113 ? 55.359 -8.212  8.550  1.00 52.92  ?  805  HIS   A H    1 
ATOM   1779 H  HA   . HIS   A 1 113 ? 56.192 -7.397  5.784  1.00 45.27  ?  805  HIS   A HA   1 
ATOM   1780 H  HB2  . HIS   A 1 113 ? 57.639 -7.278  8.421  1.00 53.66  ?  805  HIS   A HB2  1 
ATOM   1781 H  HB3  . HIS   A 1 113 ? 58.321 -6.793  6.901  1.00 53.66  ?  805  HIS   A HB3  1 
ATOM   1782 H  HD2  . HIS   A 1 113 ? 55.610 -5.473  9.531  1.00 63.31  ?  805  HIS   A HD2  1 
ATOM   1783 H  HE1  . HIS   A 1 113 ? 56.443 -2.460  6.731  1.00 65.83  ?  805  HIS   A HE1  1 
ATOM   1784 H  HE2  . HIS   A 1 113 ? 55.274 -3.010  8.877  1.00 56.48  ?  805  HIS   A HE2  1 
ATOM   1785 N  N    . LYS   A 1 114 ? 56.567 -10.314 6.537  1.00 40.07  ?  806  LYS   A N    1 
ATOM   1786 C  CA   . LYS   A 1 114 ? 57.199 -11.621 6.302  1.00 62.64  ?  806  LYS   A CA   1 
ATOM   1787 C  C    . LYS   A 1 114 ? 58.111 -11.797 5.102  1.00 67.09  ?  806  LYS   A C    1 
ATOM   1788 O  O    . LYS   A 1 114 ? 59.262 -12.222 5.214  1.00 84.32  ?  806  LYS   A O    1 
ATOM   1789 C  CB   . LYS   A 1 114 ? 56.232 -12.787 6.446  1.00 63.27  ?  806  LYS   A CB   1 
ATOM   1790 C  CG   . LYS   A 1 114 ? 54.896 -12.696 5.705  1.00 63.04  ?  806  LYS   A CG   1 
ATOM   1791 C  CD   . LYS   A 1 114 ? 53.994 -13.886 6.031  1.00 72.74  ?  806  LYS   A CD   1 
ATOM   1792 C  CE   . LYS   A 1 114 ? 53.368 -13.823 7.425  1.00 78.42  ?  806  LYS   A CE   1 
ATOM   1793 N  NZ   . LYS   A 1 114 ? 52.952 -15.145 7.918  1.00 73.33  1  806  LYS   A NZ   1 
ATOM   1794 H  H    . LYS   A 1 114 ? 55.666 -10.291 6.995  1.00 42.07  ?  806  LYS   A H    1 
ATOM   1795 H  HA   . LYS   A 1 114 ? 57.886 -11.727 7.142  1.00 64.64  ?  806  LYS   A HA   1 
ATOM   1796 H  HB2  . LYS   A 1 114 ? 56.736 -13.714 6.164  1.00 65.27  ?  806  LYS   A HB2  1 
ATOM   1797 H  HB3  . LYS   A 1 114 ? 56.046 -12.895 7.505  1.00 65.27  ?  806  LYS   A HB3  1 
ATOM   1798 H  HG2  . LYS   A 1 114 ? 54.376 -11.767 5.944  1.00 65.04  ?  806  LYS   A HG2  1 
ATOM   1799 H  HG3  . LYS   A 1 114 ? 55.083 -12.672 4.631  1.00 65.04  ?  806  LYS   A HG3  1 
ATOM   1800 H  HD2  . LYS   A 1 114 ? 53.193 -13.945 5.292  1.00 74.74  ?  806  LYS   A HD2  1 
ATOM   1801 H  HD3  . LYS   A 1 114 ? 54.570 -14.805 5.918  1.00 74.74  ?  806  LYS   A HD3  1 
ATOM   1802 H  HE2  . LYS   A 1 114 ? 54.061 -13.414 8.154  1.00 80.42  ?  806  LYS   A HE2  1 
ATOM   1803 H  HE3  . LYS   A 1 114 ? 52.497 -13.168 7.417  1.00 80.42  ?  806  LYS   A HE3  1 
ATOM   1804 H  HZ1  . LYS   A 1 114 ? 52.635 -15.056 8.874  1.00 75.33  ?  806  LYS   A HZ1  1 
ATOM   1805 H  HZ2  . LYS   A 1 114 ? 52.209 -15.511 7.343  1.00 75.33  ?  806  LYS   A HZ2  1 
ATOM   1806 H  HZ3  . LYS   A 1 114 ? 53.740 -15.776 7.895  1.00 75.33  ?  806  LYS   A HZ3  1 
ATOM   1807 N  N    . ASP   A 1 115 ? 57.606 -11.368 3.959  1.00 66.66  ?  807  ASP   A N    1 
ATOM   1808 C  CA   . ASP   A 1 115 ? 58.316 -11.513 2.691  1.00 65.76  ?  807  ASP   A CA   1 
ATOM   1809 C  C    . ASP   A 1 115 ? 59.500 -10.561 2.513  1.00 63.39  ?  807  ASP   A C    1 
ATOM   1810 O  O    . ASP   A 1 115 ? 60.105 -10.503 1.443  1.00 70.03  ?  807  ASP   A O    1 
ATOM   1811 C  CB   . ASP   A 1 115 ? 57.349 -11.318 1.514  1.00 69.88  ?  807  ASP   A CB   1 
ATOM   1812 C  CG   . ASP   A 1 115 ? 56.059 -12.103 1.662  1.00 76.92  ?  807  ASP   A CG   1 
ATOM   1813 O  OD1  . ASP   A 1 115 ? 56.118 -13.341 1.809  1.00 71.05  ?  807  ASP   A OD1  1 
ATOM   1814 O  OD2  . ASP   A 1 115 ? 54.975 -11.486 1.643  1.00 85.61  -1 807  ASP   A OD2  1 
ATOM   1815 H  H    . ASP   A 1 115 ? 56.673 -10.985 3.955  1.00 68.66  ?  807  ASP   A H    1 
ATOM   1816 H  HA   . ASP   A 1 115 ? 58.714 -12.529 2.636  1.00 67.76  ?  807  ASP   A HA   1 
ATOM   1817 H  HB2  . ASP   A 1 115 ? 57.102 -10.261 1.396  1.00 71.88  ?  807  ASP   A HB2  1 
ATOM   1818 H  HB3  . ASP   A 1 115 ? 57.826 -11.626 0.582  1.00 71.88  ?  807  ASP   A HB3  1 
ATOM   1819 N  N    . ASN   A 1 116 ? 59.819 -9.810  3.556  1.00 61.43  ?  808  ASN   A N    1 
ATOM   1820 C  CA   . ASN   A 1 116 ? 60.872 -8.811  3.532  1.00 60.76  ?  808  ASN   A CA   1 
ATOM   1821 C  C    . ASN   A 1 116 ? 61.761 -8.889  4.772  1.00 51.96  ?  808  ASN   A C    1 
ATOM   1822 O  O    . ASN   A 1 116 ? 62.661 -8.071  4.961  1.00 58.97  ?  808  ASN   A O    1 
ATOM   1823 C  CB   . ASN   A 1 116 ? 60.241 -7.447  3.269  1.00 76.07  ?  808  ASN   A CB   1 
ATOM   1824 C  CG   . ASN   A 1 116 ? 61.197 -6.367  2.821  1.00 96.27  ?  808  ASN   A CG   1 
ATOM   1825 O  OD1  . ASN   A 1 116 ? 62.240 -6.629  2.219  1.00 105.56 ?  808  ASN   A OD1  1 
ATOM   1826 N  ND2  . ASN   A 1 116 ? 60.857 -5.135  3.115  1.00 101.43 ?  808  ASN   A ND2  1 
ATOM   1827 H  H    . ASN   A 1 116 ? 59.254 -9.871  4.398  1.00 63.43  ?  808  ASN   A H    1 
ATOM   1828 H  HA   . ASN   A 1 116 ? 61.552 -9.028  2.707  1.00 62.76  ?  808  ASN   A HA   1 
ATOM   1829 H  HB2  . ASN   A 1 116 ? 59.484 -7.532  2.489  1.00 78.07  ?  808  ASN   A HB2  1 
ATOM   1830 H  HB3  . ASN   A 1 116 ? 59.716 -7.122  4.170  1.00 78.07  ?  808  ASN   A HB3  1 
ATOM   1831 H  HD21 . ASN   A 1 116 ? 59.999 -4.949  3.611  1.00 103.43 ?  808  ASN   A HD21 1 
ATOM   1832 H  HD22 . ASN   A 1 116 ? 61.485 -4.370  2.874  1.00 103.43 ?  808  ASN   A HD22 1 
ATOM   1833 N  N    . ILE   A 1 117 ? 61.533 -9.883  5.625  1.00 48.74  ?  809  ILE   A N    1 
ATOM   1834 C  CA   . ILE   A 1 117 ? 62.354 -10.057 6.818  1.00 46.76  ?  809  ILE   A CA   1 
ATOM   1835 C  C    . ILE   A 1 117 ? 63.401 -11.117 6.512  1.00 36.38  ?  809  ILE   A C    1 
ATOM   1836 O  O    . ILE   A 1 117 ? 63.077 -12.253 6.169  1.00 39.32  ?  809  ILE   A O    1 
ATOM   1837 C  CB   . ILE   A 1 117 ? 61.462 -10.480 7.998  1.00 42.86  ?  809  ILE   A CB   1 
ATOM   1838 C  CG1  . ILE   A 1 117 ? 60.570 -9.314  8.422  1.00 51.06  ?  809  ILE   A CG1  1 
ATOM   1839 C  CG2  . ILE   A 1 117 ? 62.227 -11.025 9.203  1.00 39.57  ?  809  ILE   A CG2  1 
ATOM   1840 C  CD1  . ILE   A 1 117 ? 59.390 -9.725  9.280  1.00 37.12  ?  809  ILE   A CD1  1 
ATOM   1841 H  H    . ILE   A 1 117 ? 60.861 -10.604 5.392  1.00 50.74  ?  809  ILE   A H    1 
ATOM   1842 H  HA   . ILE   A 1 117 ? 62.858 -9.132  7.108  1.00 48.76  ?  809  ILE   A HA   1 
ATOM   1843 H  HB   . ILE   A 1 117 ? 60.814 -11.279 7.635  1.00 44.86  ?  809  ILE   A HB   1 
ATOM   1844 H  HG12 . ILE   A 1 117 ? 61.160 -8.564  8.945  1.00 53.06  ?  809  ILE   A HG12 1 
ATOM   1845 H  HG13 . ILE   A 1 117 ? 60.176 -8.799  7.548  1.00 53.06  ?  809  ILE   A HG13 1 
ATOM   1846 H  HG21 . ILE   A 1 117 ? 61.562 -11.315 10.014 1.00 41.57  ?  809  ILE   A HG21 1 
ATOM   1847 H  HG22 . ILE   A 1 117 ? 62.786 -11.928 8.958  1.00 41.57  ?  809  ILE   A HG22 1 
ATOM   1848 H  HG23 . ILE   A 1 117 ? 62.932 -10.293 9.598  1.00 41.57  ?  809  ILE   A HG23 1 
ATOM   1849 H  HD11 . ILE   A 1 117 ? 58.769 -8.861  9.512  1.00 39.12  ?  809  ILE   A HD11 1 
ATOM   1850 H  HD12 . ILE   A 1 117 ? 58.766 -10.464 8.781  1.00 39.12  ?  809  ILE   A HD12 1 
ATOM   1851 H  HD13 . ILE   A 1 117 ? 59.714 -10.147 10.226 1.00 39.12  ?  809  ILE   A HD13 1 
ATOM   1852 N  N    . GLY   A 1 118 ? 64.657 -10.753 6.709  1.00 36.05  ?  810  GLY   A N    1 
ATOM   1853 C  CA   . GLY   A 1 118 ? 65.724 -11.710 6.504  1.00 34.21  ?  810  GLY   A CA   1 
ATOM   1854 C  C    . GLY   A 1 118 ? 66.259 -12.289 7.797  1.00 47.05  ?  810  GLY   A C    1 
ATOM   1855 O  O    . GLY   A 1 118 ? 65.923 -11.858 8.907  1.00 33.46  ?  810  GLY   A O    1 
ATOM   1856 H  H    . GLY   A 1 118 ? 64.869 -9.831  7.057  1.00 38.05  ?  810  GLY   A H    1 
ATOM   1857 H  HA2  . GLY   A 1 118 ? 65.452 -12.518 5.821  1.00 36.21  ?  810  GLY   A HA2  1 
ATOM   1858 H  HA3  . GLY   A 1 118 ? 66.544 -11.177 6.020  1.00 36.21  ?  810  GLY   A HA3  1 
ATOM   1859 N  N    . SER   A 1 119 ? 67.125 -13.279 7.632  1.00 29.56  ?  811  SER   A N    1 
ATOM   1860 C  CA   . SER   A 1 119 ? 67.661 -14.048 8.749  1.00 36.31  ?  811  SER   A CA   1 
ATOM   1861 C  C    . SER   A 1 119 ? 68.442 -13.232 9.771  1.00 31.86  ?  811  SER   A C    1 
ATOM   1862 O  O    . SER   A 1 119 ? 68.395 -13.514 10.967 1.00 33.78  ?  811  SER   A O    1 
ATOM   1863 C  CB   . SER   A 1 119 ? 68.504 -15.210 8.236  1.00 35.73  ?  811  SER   A CB   1 
ATOM   1864 O  OG   . SER   A 1 119 ? 69.615 -14.773 7.481  1.00 35.58  ?  811  SER   A OG   1 
ATOM   1865 H  H    . SER   A 1 119 ? 67.410 -13.531 6.691  1.00 31.56  ?  811  SER   A H    1 
ATOM   1866 H  HA   . SER   A 1 119 ? 66.807 -14.473 9.281  1.00 38.31  ?  811  SER   A HA   1 
ATOM   1867 H  HB2  . SER   A 1 119 ? 68.888 -15.787 9.079  1.00 37.73  ?  811  SER   A HB2  1 
ATOM   1868 H  HB3  . SER   A 1 119 ? 67.910 -15.892 7.627  1.00 37.73  ?  811  SER   A HB3  1 
ATOM   1869 H  HG   . SER   A 1 119 ? 69.385 -14.750 6.553  1.00 37.58  ?  811  SER   A HG   1 
ATOM   1870 N  N    . GLN   A 1 120 ? 69.095 -12.180 9.287  1.00 29.39  ?  812  GLN   A N    1 
ATOM   1871 C  CA   . GLN   A 1 120 ? 69.795 -11.241 10.147 1.00 35.71  ?  812  GLN   A CA   1 
ATOM   1872 C  C    . GLN   A 1 120 ? 68.862 -10.532 11.118 1.00 37.07  ?  812  GLN   A C    1 
ATOM   1873 O  O    . GLN   A 1 120 ? 69.161 -10.438 12.303 1.00 32.15  ?  812  GLN   A O    1 
ATOM   1874 C  CB   . GLN   A 1 120 ? 70.541 -10.213 9.302  1.00 22.86  ?  812  GLN   A CB   1 
ATOM   1875 C  CG   . GLN   A 1 120 ? 71.491 -9.292  10.081 1.00 32.47  ?  812  GLN   A CG   1 
ATOM   1876 C  CD   . GLN   A 1 120 ? 72.765 -10.004 10.459 1.00 51.20  ?  812  GLN   A CD   1 
ATOM   1877 O  OE1  . GLN   A 1 120 ? 73.623 -10.268 9.623  1.00 67.26  ?  812  GLN   A OE1  1 
ATOM   1878 N  NE2  . GLN   A 1 120 ? 72.908 -10.328 11.723 1.00 46.36  ?  812  GLN   A NE2  1 
ATOM   1879 H  H    . GLN   A 1 120 ? 69.131 -12.071 8.286  1.00 31.39  ?  812  GLN   A H    1 
ATOM   1880 H  HA   . GLN   A 1 120 ? 70.519 -11.814 10.732 1.00 37.71  ?  812  GLN   A HA   1 
ATOM   1881 H  HB2  . GLN   A 1 120 ? 71.111 -10.729 8.527  1.00 24.86  ?  812  GLN   A HB2  1 
ATOM   1882 H  HB3  . GLN   A 1 120 ? 69.823 -9.592  8.763  1.00 24.86  ?  812  GLN   A HB3  1 
ATOM   1883 H  HG2  . GLN   A 1 120 ? 71.776 -8.461  9.436  1.00 34.47  ?  812  GLN   A HG2  1 
ATOM   1884 H  HG3  . GLN   A 1 120 ? 71.016 -8.836  10.950 1.00 34.47  ?  812  GLN   A HG3  1 
ATOM   1885 H  HE21 . GLN   A 1 120 ? 72.187 -10.073 12.406 1.00 48.36  ?  812  GLN   A HE21 1 
ATOM   1886 H  HE22 . GLN   A 1 120 ? 73.742 -10.828 12.022 1.00 48.36  ?  812  GLN   A HE22 1 
ATOM   1887 N  N    . TYR   A 1 121 ? 67.707 -10.094 10.622 1.00 32.39  ?  813  TYR   A N    1 
ATOM   1888 C  CA   . TYR   A 1 121 ? 66.727 -9.468  11.497 1.00 23.36  ?  813  TYR   A CA   1 
ATOM   1889 C  C    . TYR   A 1 121 ? 66.193 -10.413 12.554 1.00 33.56  ?  813  TYR   A C    1 
ATOM   1890 O  O    . TYR   A 1 121 ? 66.221 -10.085 13.742 1.00 29.22  ?  813  TYR   A O    1 
ATOM   1891 C  CB   . TYR   A 1 121 ? 65.592 -8.837  10.703 1.00 28.15  ?  813  TYR   A CB   1 
ATOM   1892 C  CG   . TYR   A 1 121 ? 65.961 -7.458  10.191 1.00 35.45  ?  813  TYR   A CG   1 
ATOM   1893 C  CD1  . TYR   A 1 121 ? 65.812 -6.340  11.030 1.00 48.23  ?  813  TYR   A CD1  1 
ATOM   1894 C  CD2  . TYR   A 1 121 ? 66.460 -7.293  8.882  1.00 49.43  ?  813  TYR   A CD2  1 
ATOM   1895 C  CE1  . TYR   A 1 121 ? 66.157 -5.058  10.566 1.00 51.15  ?  813  TYR   A CE1  1 
ATOM   1896 C  CE2  . TYR   A 1 121 ? 66.805 -6.007  8.419  1.00 45.82  ?  813  TYR   A CE2  1 
ATOM   1897 C  CZ   . TYR   A 1 121 ? 66.651 -4.889  9.264  1.00 54.56  ?  813  TYR   A CZ   1 
ATOM   1898 O  OH   . TYR   A 1 121 ? 66.981 -3.641  8.821  1.00 53.98  ?  813  TYR   A OH   1 
ATOM   1899 H  H    . TYR   A 1 121 ? 67.445 -10.340 9.680  1.00 34.39  ?  813  TYR   A H    1 
ATOM   1900 H  HA   . TYR   A 1 121 ? 67.229 -8.669  12.047 1.00 25.36  ?  813  TYR   A HA   1 
ATOM   1901 H  HB2  . TYR   A 1 121 ? 65.276 -9.478  9.880  1.00 30.15  ?  813  TYR   A HB2  1 
ATOM   1902 H  HB3  . TYR   A 1 121 ? 64.709 -8.719  11.334 1.00 30.15  ?  813  TYR   A HB3  1 
ATOM   1903 H  HD1  . TYR   A 1 121 ? 65.431 -6.466  12.034 1.00 50.23  ?  813  TYR   A HD1  1 
ATOM   1904 H  HD2  . TYR   A 1 121 ? 66.580 -8.149  8.236  1.00 51.43  ?  813  TYR   A HD2  1 
ATOM   1905 H  HE1  . TYR   A 1 121 ? 66.041 -4.204  11.213 1.00 53.15  ?  813  TYR   A HE1  1 
ATOM   1906 H  HE2  . TYR   A 1 121 ? 67.187 -5.882  7.417  1.00 47.82  ?  813  TYR   A HE2  1 
ATOM   1907 H  HH   . TYR   A 1 121 ? 67.304 -3.639  7.929  1.00 55.98  ?  813  TYR   A HH   1 
ATOM   1908 N  N    . LEU   A 1 122 ? 65.799 -11.611 12.121 1.00 25.66  ?  814  LEU   A N    1 
ATOM   1909 C  CA   . LEU   A 1 122 ? 65.289 -12.622 13.045 1.00 34.98  ?  814  LEU   A CA   1 
ATOM   1910 C  C    . LEU   A 1 122 ? 66.264 -12.985 14.157 1.00 34.72  ?  814  LEU   A C    1 
ATOM   1911 O  O    . LEU   A 1 122 ? 65.908 -12.987 15.340 1.00 33.91  ?  814  LEU   A O    1 
ATOM   1912 C  CB   . LEU   A 1 122 ? 64.835 -13.877 12.297 1.00 33.63  ?  814  LEU   A CB   1 
ATOM   1913 C  CG   . LEU   A 1 122 ? 63.607 -13.675 11.408 1.00 43.88  ?  814  LEU   A CG   1 
ATOM   1914 C  CD1  . LEU   A 1 122 ? 63.545 -14.716 10.306 1.00 32.03  ?  814  LEU   A CD1  1 
ATOM   1915 C  CD2  . LEU   A 1 122 ? 62.311 -13.691 12.207 1.00 35.15  ?  814  LEU   A CD2  1 
ATOM   1916 H  H    . LEU   A 1 122 ? 65.858 -11.824 11.133 1.00 27.66  ?  814  LEU   A H    1 
ATOM   1917 H  HA   . LEU   A 1 122 ? 64.420 -12.191 13.545 1.00 36.98  ?  814  LEU   A HA   1 
ATOM   1918 H  HB2  . LEU   A 1 122 ? 65.672 -14.231 11.693 1.00 35.63  ?  814  LEU   A HB2  1 
ATOM   1919 H  HB3  . LEU   A 1 122 ? 64.630 -14.685 13.002 1.00 35.63  ?  814  LEU   A HB3  1 
ATOM   1920 H  HG   . LEU   A 1 122 ? 63.693 -12.705 10.922 1.00 45.88  ?  814  LEU   A HG   1 
ATOM   1921 H  HD11 . LEU   A 1 122 ? 62.683 -14.561 9.657  1.00 34.03  ?  814  LEU   A HD11 1 
ATOM   1922 H  HD12 . LEU   A 1 122 ? 64.435 -14.670 9.680  1.00 34.03  ?  814  LEU   A HD12 1 
ATOM   1923 H  HD13 . LEU   A 1 122 ? 63.472 -15.722 10.719 1.00 34.03  ?  814  LEU   A HD13 1 
ATOM   1924 H  HD21 . LEU   A 1 122 ? 61.445 -13.530 11.562 1.00 37.15  ?  814  LEU   A HD21 1 
ATOM   1925 H  HD22 . LEU   A 1 122 ? 62.170 -14.649 12.708 1.00 37.15  ?  814  LEU   A HD22 1 
ATOM   1926 H  HD23 . LEU   A 1 122 ? 62.294 -12.915 12.969 1.00 37.15  ?  814  LEU   A HD23 1 
ATOM   1927 N  N    . LEU   A 1 123 ? 67.511 -13.235 13.770 1.00 28.21  ?  815  LEU   A N    1 
ATOM   1928 C  CA   . LEU   A 1 123 ? 68.512 -13.603 14.754 1.00 24.28  ?  815  LEU   A CA   1 
ATOM   1929 C  C    . LEU   A 1 123 ? 68.907 -12.443 15.658 1.00 25.24  ?  815  LEU   A C    1 
ATOM   1930 O  O    . LEU   A 1 123 ? 69.089 -12.643 16.862 1.00 29.59  ?  815  LEU   A O    1 
ATOM   1931 C  CB   . LEU   A 1 123 ? 69.744 -14.206 14.082 1.00 27.79  ?  815  LEU   A CB   1 
ATOM   1932 C  CG   . LEU   A 1 123 ? 69.485 -15.536 13.364 1.00 32.04  ?  815  LEU   A CG   1 
ATOM   1933 C  CD1  . LEU   A 1 123 ? 70.633 -15.869 12.436 1.00 20.97  ?  815  LEU   A CD1  1 
ATOM   1934 C  CD2  . LEU   A 1 123 ? 69.225 -16.704 14.312 1.00 30.78  ?  815  LEU   A CD2  1 
ATOM   1935 H  H    . LEU   A 1 123 ? 67.768 -13.186 12.787 1.00 30.21  ?  815  LEU   A H    1 
ATOM   1936 H  HA   . LEU   A 1 123 ? 68.087 -14.363 15.413 1.00 26.28  ?  815  LEU   A HA   1 
ATOM   1937 H  HB2  . LEU   A 1 123 ? 70.136 -13.476 13.371 1.00 29.79  ?  815  LEU   A HB2  1 
ATOM   1938 H  HB3  . LEU   A 1 123 ? 70.538 -14.351 14.818 1.00 29.79  ?  815  LEU   A HB3  1 
ATOM   1939 H  HG   . LEU   A 1 123 ? 68.602 -15.422 12.736 1.00 34.04  ?  815  LEU   A HG   1 
ATOM   1940 H  HD11 . LEU   A 1 123 ? 70.417 -16.753 11.836 1.00 22.97  ?  815  LEU   A HD11 1 
ATOM   1941 H  HD12 . LEU   A 1 123 ? 70.822 -15.050 11.742 1.00 22.97  ?  815  LEU   A HD12 1 
ATOM   1942 H  HD13 . LEU   A 1 123 ? 71.553 -16.056 12.987 1.00 22.97  ?  815  LEU   A HD13 1 
ATOM   1943 H  HD21 . LEU   A 1 123 ? 69.046 -17.625 13.755 1.00 32.78  ?  815  LEU   A HD21 1 
ATOM   1944 H  HD22 . LEU   A 1 123 ? 70.082 -16.881 14.963 1.00 32.78  ?  815  LEU   A HD22 1 
ATOM   1945 H  HD23 . LEU   A 1 123 ? 68.348 -16.540 14.937 1.00 32.78  ?  815  LEU   A HD23 1 
ATOM   1946 N  N    . ASN   A 1 124 ? 68.967 -11.228 15.120 1.00 21.93  ?  816  ASN   A N    1 
ATOM   1947 C  CA   . ASN   A 1 124 ? 69.182 -10.070 15.984 1.00 29.98  ?  816  ASN   A CA   1 
ATOM   1948 C  C    . ASN   A 1 124 ? 68.052 -9.794  16.956 1.00 32.07  ?  816  ASN   A C    1 
ATOM   1949 O  O    . ASN   A 1 124 ? 68.313 -9.458  18.115 1.00 29.32  ?  816  ASN   A O    1 
ATOM   1950 C  CB   . ASN   A 1 124 ? 69.529 -8.806  15.207 1.00 40.61  ?  816  ASN   A CB   1 
ATOM   1951 C  CG   . ASN   A 1 124 ? 70.976 -8.852  14.777 1.00 52.80  ?  816  ASN   A CG   1 
ATOM   1952 O  OD1  . ASN   A 1 124 ? 71.314 -9.336  13.707 1.00 61.96  ?  816  ASN   A OD1  1 
ATOM   1953 N  ND2  . ASN   A 1 124 ? 71.852 -8.357  15.616 1.00 75.51  ?  816  ASN   A ND2  1 
ATOM   1954 H  H    . ASN   A 1 124 ? 68.828 -11.085 14.123 1.00 23.93  ?  816  ASN   A H    1 
ATOM   1955 H  HA   . ASN   A 1 124 ? 70.037 -10.301 16.626 1.00 31.98  ?  816  ASN   A HA   1 
ATOM   1956 H  HB2  . ASN   A 1 124 ? 68.879 -8.688  14.339 1.00 42.61  ?  816  ASN   A HB2  1 
ATOM   1957 H  HB3  . ASN   A 1 124 ? 69.379 -7.913  15.818 1.00 42.61  ?  816  ASN   A HB3  1 
ATOM   1958 H  HD21 . ASN   A 1 124 ? 71.540 -7.951  16.499 1.00 77.51  ?  816  ASN   A HD21 1 
ATOM   1959 H  HD22 . ASN   A 1 124 ? 72.832 -8.374  15.384 1.00 77.51  ?  816  ASN   A HD22 1 
ATOM   1960 N  N    . TRP   A 1 125 ? 66.809 -10.016 16.534 1.00 23.81  ?  817  TRP   A N    1 
ATOM   1961 C  CA   . TRP   A 1 125 ? 65.692 -9.913  17.474 1.00 33.39  ?  817  TRP   A CA   1 
ATOM   1962 C  C    . TRP   A 1 125 ? 65.776 -10.921 18.607 1.00 32.22  ?  817  TRP   A C    1 
ATOM   1963 O  O    . TRP   A 1 125 ? 65.508 -10.576 19.760 1.00 34.14  ?  817  TRP   A O    1 
ATOM   1964 C  CB   . TRP   A 1 125 ? 64.335 -10.024 16.787 1.00 20.82  ?  817  TRP   A CB   1 
ATOM   1965 C  CG   . TRP   A 1 125 ? 64.010 -8.967  15.771 1.00 29.30  ?  817  TRP   A CG   1 
ATOM   1966 C  CD1  . TRP   A 1 125 ? 64.470 -7.692  15.784 1.00 22.40  ?  817  TRP   A CD1  1 
ATOM   1967 C  CD2  . TRP   A 1 125 ? 63.176 -9.078  14.577 1.00 17.83  ?  817  TRP   A CD2  1 
ATOM   1968 N  NE1  . TRP   A 1 125 ? 63.982 -7.015  14.686 1.00 21.36  ?  817  TRP   A NE1  1 
ATOM   1969 C  CE2  . TRP   A 1 125 ? 63.181 -7.817  13.902 1.00 29.14  ?  817  TRP   A CE2  1 
ATOM   1970 C  CE3  . TRP   A 1 125 ? 62.418 -10.118 13.981 1.00 30.54  ?  817  TRP   A CE3  1 
ATOM   1971 C  CZ2  . TRP   A 1 125 ? 62.482 -7.597  12.711 1.00 23.86  ?  817  TRP   A CZ2  1 
ATOM   1972 C  CZ3  . TRP   A 1 125 ? 61.710 -9.902  12.777 1.00 33.27  ?  817  TRP   A CZ3  1 
ATOM   1973 C  CH2  . TRP   A 1 125 ? 61.742 -8.643  12.144 1.00 27.54  ?  817  TRP   A CH2  1 
ATOM   1974 H  H    . TRP   A 1 125 ? 66.627 -10.228 15.554 1.00 25.81  ?  817  TRP   A H    1 
ATOM   1975 H  HA   . TRP   A 1 125 ? 65.744 -8.931  17.948 1.00 35.39  ?  817  TRP   A HA   1 
ATOM   1976 H  HB2  . TRP   A 1 125 ? 64.266 -10.990 16.285 1.00 22.82  ?  817  TRP   A HB2  1 
ATOM   1977 H  HB3  . TRP   A 1 125 ? 63.533 -10.011 17.528 1.00 22.82  ?  817  TRP   A HB3  1 
ATOM   1978 H  HD1  . TRP   A 1 125 ? 65.125 -7.284  16.540 1.00 24.40  ?  817  TRP   A HD1  1 
ATOM   1979 H  HE1  . TRP   A 1 125 ? 64.217 -6.038  14.482 1.00 23.36  ?  817  TRP   A HE1  1 
ATOM   1980 H  HE3  . TRP   A 1 125 ? 62.386 -11.088 14.452 1.00 32.54  ?  817  TRP   A HE3  1 
ATOM   1981 H  HZ2  . TRP   A 1 125 ? 62.513 -6.629  12.233 1.00 25.86  ?  817  TRP   A HZ2  1 
ATOM   1982 H  HZ3  . TRP   A 1 125 ? 61.147 -10.710 12.338 1.00 35.27  ?  817  TRP   A HZ3  1 
ATOM   1983 H  HH2  . TRP   A 1 125 ? 61.200 -8.485  11.226 1.00 29.54  ?  817  TRP   A HH2  1 
ATOM   1984 N  N    . CYS   A 1 126 ? 66.220 -12.136 18.285 1.00 27.72  ?  818  CYS   A N    1 
ATOM   1985 C  CA   . CYS   A 1 126 ? 66.462 -13.137 19.321 1.00 20.52  ?  818  CYS   A CA   1 
ATOM   1986 C  C    . CYS   A 1 126 ? 67.540 -12.738 20.323 1.00 25.85  ?  818  CYS   A C    1 
ATOM   1987 O  O    . CYS   A 1 126 ? 67.369 -12.962 21.523 1.00 31.09  ?  818  CYS   A O    1 
ATOM   1988 C  CB   . CYS   A 1 126 ? 66.772 -14.501 18.728 1.00 24.66  ?  818  CYS   A CB   1 
ATOM   1989 S  SG   . CYS   A 1 126 ? 65.466 -15.187 17.691 1.00 27.91  ?  818  CYS   A SG   1 
ATOM   1990 H  H    . CYS   A 1 126 ? 66.417 -12.352 17.314 1.00 29.72  ?  818  CYS   A H    1 
ATOM   1991 H  HA   . CYS   A 1 126 ? 65.535 -13.244 19.890 1.00 22.52  ?  818  CYS   A HA   1 
ATOM   1992 H  HB2  . CYS   A 1 126 ? 67.688 -14.462 18.138 1.00 26.66  ?  818  CYS   A HB2  1 
ATOM   1993 H  HB3  . CYS   A 1 126 ? 66.961 -15.224 19.523 1.00 26.66  ?  818  CYS   A HB3  1 
ATOM   1994 H  HG   . CYS   A 1 126 ? 65.501 -14.220 16.759 1.00 29.91  ?  818  CYS   A HG   1 
ATOM   1995 N  N    . VAL   A 1 127 ? 68.610 -12.098 19.844 1.00 20.82  ?  819  VAL   A N    1 
ATOM   1996 C  CA   . VAL   A 1 127 ? 69.652 -11.563 20.725 1.00 26.78  ?  819  VAL   A CA   1 
ATOM   1997 C  C    . VAL   A 1 127 ? 69.128 -10.461 21.643 1.00 29.72  ?  819  VAL   A C    1 
ATOM   1998 O  O    . VAL   A 1 127 ? 69.419 -10.449 22.841 1.00 29.63  ?  819  VAL   A O    1 
ATOM   1999 C  CB   . VAL   A 1 127 ? 70.861 -11.059 19.908 1.00 25.18  ?  819  VAL   A CB   1 
ATOM   2000 C  CG1  . VAL   A 1 127 ? 71.923 -10.336 20.737 1.00 21.99  ?  819  VAL   A CG1  1 
ATOM   2001 C  CG2  . VAL   A 1 127 ? 71.537 -12.183 19.142 1.00 23.55  ?  819  VAL   A CG2  1 
ATOM   2002 H  H    . VAL   A 1 127 ? 68.689 -11.950 18.844 1.00 22.82  ?  819  VAL   A H    1 
ATOM   2003 H  HA   . VAL   A 1 127 ? 69.994 -12.375 21.370 1.00 28.78  ?  819  VAL   A HA   1 
ATOM   2004 H  HB   . VAL   A 1 127 ? 70.499 -10.342 19.171 1.00 27.18  ?  819  VAL   A HB   1 
ATOM   2005 H  HG11 . VAL   A 1 127 ? 72.800 -10.099 20.134 1.00 23.99  ?  819  VAL   A HG11 1 
ATOM   2006 H  HG12 . VAL   A 1 127 ? 71.564 -9.391  21.143 1.00 23.99  ?  819  VAL   A HG12 1 
ATOM   2007 H  HG13 . VAL   A 1 127 ? 72.263 -10.954 21.569 1.00 23.99  ?  819  VAL   A HG13 1 
ATOM   2008 H  HG21 . VAL   A 1 127 ? 72.333 -11.806 18.499 1.00 25.55  ?  819  VAL   A HG21 1 
ATOM   2009 H  HG22 . VAL   A 1 127 ? 71.985 -12.900 19.830 1.00 25.55  ?  819  VAL   A HG22 1 
ATOM   2010 H  HG23 . VAL   A 1 127 ? 70.850 -12.730 18.507 1.00 25.55  ?  819  VAL   A HG23 1 
ATOM   2011 N  N    . GLN   A 1 128 ? 68.350 -9.550  21.068 1.00 29.76  ?  820  GLN   A N    1 
ATOM   2012 C  CA   . GLN   A 1 128 ? 67.848 -8.399  21.808 1.00 30.91  ?  820  GLN   A CA   1 
ATOM   2013 C  C    . GLN   A 1 128 ? 66.846 -8.763  22.892 1.00 31.67  ?  820  GLN   A C    1 
ATOM   2014 O  O    . GLN   A 1 128 ? 66.927 -8.257  24.015 1.00 27.60  ?  820  GLN   A O    1 
ATOM   2015 C  CB   . GLN   A 1 128 ? 67.245 -7.389  20.848 1.00 22.71  ?  820  GLN   A CB   1 
ATOM   2016 C  CG   . GLN   A 1 128 ? 68.328 -6.697  20.004 1.00 22.65  ?  820  GLN   A CG   1 
ATOM   2017 C  CD   . GLN   A 1 128 ? 67.754 -5.674  19.046 1.00 32.01  ?  820  GLN   A CD   1 
ATOM   2018 O  OE1  . GLN   A 1 128 ? 66.626 -5.210  19.197 1.00 31.72  ?  820  GLN   A OE1  1 
ATOM   2019 N  NE2  . GLN   A 1 128 ? 68.524 -5.311  18.049 1.00 39.54  ?  820  GLN   A NE2  1 
ATOM   2020 H  H    . GLN   A 1 128 ? 68.161 -9.618  20.072 1.00 31.76  ?  820  GLN   A H    1 
ATOM   2021 H  HA   . GLN   A 1 128 ? 68.688 -7.921  22.317 1.00 32.91  ?  820  GLN   A HA   1 
ATOM   2022 H  HB2  . GLN   A 1 128 ? 66.511 -7.871  20.200 1.00 24.71  ?  820  GLN   A HB2  1 
ATOM   2023 H  HB3  . GLN   A 1 128 ? 66.697 -6.630  21.411 1.00 24.71  ?  820  GLN   A HB3  1 
ATOM   2024 H  HG2  . GLN   A 1 128 ? 69.050 -6.201  20.652 1.00 24.65  ?  820  GLN   A HG2  1 
ATOM   2025 H  HG3  . GLN   A 1 128 ? 68.892 -7.434  19.436 1.00 24.65  ?  820  GLN   A HG3  1 
ATOM   2026 H  HE21 . GLN   A 1 128 ? 69.450 -5.716  17.944 1.00 41.54  ?  820  GLN   A HE21 1 
ATOM   2027 H  HE22 . GLN   A 1 128 ? 68.192 -4.619  17.375 1.00 41.54  ?  820  GLN   A HE22 1 
ATOM   2028 N  N    . ILE   A 1 129 ? 65.946 -9.696  22.582 1.00 31.63  ?  821  ILE   A N    1 
ATOM   2029 C  CA   . ILE   A 1 129 ? 65.017 -10.191 23.593 1.00 24.39  ?  821  ILE   A CA   1 
ATOM   2030 C  C    . ILE   A 1 129 ? 65.766 -10.944 24.696 1.00 38.39  ?  821  ILE   A C    1 
ATOM   2031 O  O    . ILE   A 1 129 ? 65.459 -10.794 25.877 1.00 35.61  ?  821  ILE   A O    1 
ATOM   2032 C  CB   . ILE   A 1 129 ? 63.907 -11.059 22.961 1.00 32.17  ?  821  ILE   A CB   1 
ATOM   2033 C  CG1  . ILE   A 1 129 ? 63.074 -10.270 21.939 1.00 25.06  ?  821  ILE   A CG1  1 
ATOM   2034 C  CG2  . ILE   A 1 129 ? 62.970 -11.697 24.001 1.00 20.03  ?  821  ILE   A CG2  1 
ATOM   2035 C  CD1  . ILE   A 1 129 ? 62.292 -11.163 20.975 1.00 25.22  ?  821  ILE   A CD1  1 
ATOM   2036 H  H    . ILE   A 1 129 ? 65.908 -10.069 21.637 1.00 33.63  ?  821  ILE   A H    1 
ATOM   2037 H  HA   . ILE   A 1 129 ? 64.535 -9.331  24.064 1.00 26.39  ?  821  ILE   A HA   1 
ATOM   2038 H  HB   . ILE   A 1 129 ? 64.404 -11.868 22.423 1.00 34.17  ?  821  ILE   A HB   1 
ATOM   2039 H  HG12 . ILE   A 1 129 ? 62.388 -9.601  22.461 1.00 27.06  ?  821  ILE   A HG12 1 
ATOM   2040 H  HG13 . ILE   A 1 129 ? 63.705 -9.615  21.339 1.00 27.06  ?  821  ILE   A HG13 1 
ATOM   2041 H  HG21 . ILE   A 1 129 ? 62.222 -12.341 23.540 1.00 22.03  ?  821  ILE   A HG21 1 
ATOM   2042 H  HG22 . ILE   A 1 129 ? 63.497 -12.315 24.722 1.00 22.03  ?  821  ILE   A HG22 1 
ATOM   2043 H  HG23 . ILE   A 1 129 ? 62.438 -10.934 24.570 1.00 22.03  ?  821  ILE   A HG23 1 
ATOM   2044 H  HD11 . ILE   A 1 129 ? 61.753 -10.560 20.245 1.00 27.22  ?  821  ILE   A HD11 1 
ATOM   2045 H  HD12 . ILE   A 1 129 ? 62.964 -11.816 20.417 1.00 27.22  ?  821  ILE   A HD12 1 
ATOM   2046 H  HD13 . ILE   A 1 129 ? 61.560 -11.789 21.482 1.00 27.22  ?  821  ILE   A HD13 1 
ATOM   2047 N  N    . ALA   A 1 130 ? 66.793 -11.707 24.328 1.00 33.80  ?  822  ALA   A N    1 
ATOM   2048 C  CA   . ALA   A 1 130 ? 67.574 -12.393 25.344 1.00 33.73  ?  822  ALA   A CA   1 
ATOM   2049 C  C    . ALA   A 1 130 ? 68.367 -11.429 26.227 1.00 32.32  ?  822  ALA   A C    1 
ATOM   2050 O  O    . ALA   A 1 130 ? 68.492 -11.655 27.427 1.00 24.55  ?  822  ALA   A O    1 
ATOM   2051 C  CB   . ALA   A 1 130 ? 68.492 -13.418 24.705 1.00 25.71  ?  822  ALA   A CB   1 
ATOM   2052 H  H    . ALA   A 1 130 ? 67.059 -11.778 23.353 1.00 35.80  ?  822  ALA   A H    1 
ATOM   2053 H  HA   . ALA   A 1 130 ? 66.889 -12.942 25.995 1.00 35.73  ?  822  ALA   A HA   1 
ATOM   2054 H  HB1  . ALA   A 1 130 ? 69.031 -13.984 25.464 1.00 27.71  ?  822  ALA   A HB1  1 
ATOM   2055 H  HB2  . ALA   A 1 130 ? 67.930 -14.142 24.121 1.00 27.71  ?  822  ALA   A HB2  1 
ATOM   2056 H  HB3  . ALA   A 1 130 ? 69.225 -12.955 24.044 1.00 27.71  ?  822  ALA   A HB3  1 
ATOM   2057 N  N    . LYS   A 1 131 ? 68.840 -10.319 25.662 1.00 29.45  ?  823  LYS   A N    1 
ATOM   2058 C  CA   . LYS   A 1 131 ? 69.450 -9.268  26.477 1.00 23.55  ?  823  LYS   A CA   1 
ATOM   2059 C  C    . LYS   A 1 131 ? 68.471 -8.599  27.428 1.00 33.66  ?  823  LYS   A C    1 
ATOM   2060 O  O    . LYS   A 1 131 ? 68.776 -8.397  28.607 1.00 29.45  ?  823  LYS   A O    1 
ATOM   2061 C  CB   . LYS   A 1 131 ? 70.103 -8.202  25.616 1.00 19.37  ?  823  LYS   A CB   1 
ATOM   2062 C  CG   . LYS   A 1 131 ? 71.453 -8.618  25.050 1.00 24.57  ?  823  LYS   A CG   1 
ATOM   2063 C  CD   . LYS   A 1 131 ? 72.036 -7.548  24.133 1.00 24.05  ?  823  LYS   A CD   1 
ATOM   2064 C  CE   . LYS   A 1 131 ? 73.430 -7.910  23.633 1.00 23.09  ?  823  LYS   A CE   1 
ATOM   2065 N  NZ   . LYS   A 1 131 ? 73.965 -6.849  22.772 1.00 31.75  1  823  LYS   A NZ   1 
ATOM   2066 H  H    . LYS   A 1 131 ? 68.766 -10.198 24.656 1.00 31.45  ?  823  LYS   A H    1 
ATOM   2067 H  HA   . LYS   A 1 131 ? 70.223 -9.711  27.106 1.00 25.55  ?  823  LYS   A HA   1 
ATOM   2068 H  HB2  . LYS   A 1 131 ? 69.430 -7.913  24.809 1.00 21.37  ?  823  LYS   A HB2  1 
ATOM   2069 H  HB3  . LYS   A 1 131 ? 70.262 -7.296  26.205 1.00 21.37  ?  823  LYS   A HB3  1 
ATOM   2070 H  HG2  . LYS   A 1 131 ? 72.144 -8.805  25.872 1.00 26.57  ?  823  LYS   A HG2  1 
ATOM   2071 H  HG3  . LYS   A 1 131 ? 71.355 -9.557  24.503 1.00 26.57  ?  823  LYS   A HG3  1 
ATOM   2072 H  HD2  . LYS   A 1 131 ? 71.367 -7.394  23.284 1.00 26.05  ?  823  LYS   A HD2  1 
ATOM   2073 H  HD3  . LYS   A 1 131 ? 72.079 -6.598  24.668 1.00 26.05  ?  823  LYS   A HD3  1 
ATOM   2074 H  HE2  . LYS   A 1 131 ? 74.117 -8.056  24.469 1.00 25.09  ?  823  LYS   A HE2  1 
ATOM   2075 H  HE3  . LYS   A 1 131 ? 73.409 -8.843  23.069 1.00 25.09  ?  823  LYS   A HE3  1 
ATOM   2076 H  HZ1  . LYS   A 1 131 ? 74.894 -7.118  22.458 1.00 33.75  ?  823  LYS   A HZ1  1 
ATOM   2077 H  HZ2  . LYS   A 1 131 ? 73.367 -6.719  21.971 1.00 33.75  ?  823  LYS   A HZ2  1 
ATOM   2078 H  HZ3  . LYS   A 1 131 ? 74.032 -5.986  23.291 1.00 33.75  ?  823  LYS   A HZ3  1 
ATOM   2079 N  N    . GLY   A 1 132 ? 67.259 -8.338  26.944 1.00 31.13  ?  824  GLY   A N    1 
ATOM   2080 C  CA   . GLY   A 1 132 ? 66.296 -7.704  27.822 1.00 30.66  ?  824  GLY   A CA   1 
ATOM   2081 C  C    . GLY   A 1 132 ? 65.789 -8.625  28.912 1.00 41.15  ?  824  GLY   A C    1 
ATOM   2082 O  O    . GLY   A 1 132 ? 65.654 -8.221  30.070 1.00 40.52  ?  824  GLY   A O    1 
ATOM   2083 H  H    . GLY   A 1 132 ? 67.043 -8.514  25.967 1.00 33.13  ?  824  GLY   A H    1 
ATOM   2084 H  HA2  . GLY   A 1 132 ? 66.727 -6.809  28.276 1.00 32.66  ?  824  GLY   A HA2  1 
ATOM   2085 H  HA3  . GLY   A 1 132 ? 65.469 -7.350  27.214 1.00 32.66  ?  824  GLY   A HA3  1 
ATOM   2086 N  N    . MET   A 1 133 ? 65.621 -9.896  28.569 1.00 30.48  ?  825  MET   A N    1 
ATOM   2087 C  CA   . MET   A 1 133 ? 65.258 -10.879 29.579 1.00 34.11  ?  825  MET   A CA   1 
ATOM   2088 C  C    . MET   A 1 133 ? 66.379 -11.160 30.578 1.00 23.09  ?  825  MET   A C    1 
ATOM   2089 O  O    . MET   A 1 133 ? 66.117 -11.280 31.773 1.00 25.83  ?  825  MET   A O    1 
ATOM   2090 C  CB   . MET   A 1 133 ? 64.800 -12.180 28.935 1.00 32.47  ?  825  MET   A CB   1 
ATOM   2091 C  CG   . MET   A 1 133 ? 63.483 -12.080 28.172 1.00 32.13  ?  825  MET   A CG   1 
ATOM   2092 S  SD   . MET   A 1 133 ? 62.076 -11.439 29.113 1.00 31.87  ?  825  MET   A SD   1 
ATOM   2093 C  CE   . MET   A 1 133 ? 62.117 -12.600 30.472 1.00 22.66  ?  825  MET   A CE   1 
ATOM   2094 H  H    . MET   A 1 133 ? 65.737 -10.186 27.600 1.00 32.48  ?  825  MET   A H    1 
ATOM   2095 H  HA   . MET   A 1 133 ? 64.433 -10.477 30.170 1.00 36.11  ?  825  MET   A HA   1 
ATOM   2096 H  HB2  . MET   A 1 133 ? 65.577 -12.548 28.263 1.00 34.47  ?  825  MET   A HB2  1 
ATOM   2097 H  HB3  . MET   A 1 133 ? 64.706 -12.942 29.706 1.00 34.47  ?  825  MET   A HB3  1 
ATOM   2098 H  HG2  . MET   A 1 133 ? 63.590 -11.443 27.299 1.00 34.13  ?  825  MET   A HG2  1 
ATOM   2099 H  HG3  . MET   A 1 133 ? 63.231 -13.067 27.787 1.00 34.13  ?  825  MET   A HG3  1 
ATOM   2100 H  HE1  . MET   A 1 133 ? 61.181 -12.567 31.026 1.00 24.66  ?  825  MET   A HE1  1 
ATOM   2101 H  HE2  . MET   A 1 133 ? 62.266 -13.608 30.095 1.00 24.66  ?  825  MET   A HE2  1 
ATOM   2102 H  HE3  . MET   A 1 133 ? 62.929 -12.366 31.162 1.00 24.66  ?  825  MET   A HE3  1 
ATOM   2103 N  N    . ASN   A 1 134 ? 67.632 -11.163 30.123 1.00 21.60  ?  826  ASN   A N    1 
ATOM   2104 C  CA   . ASN   A 1 134 ? 68.762 -11.299 31.049 1.00 28.49  ?  826  ASN   A CA   1 
ATOM   2105 C  C    . ASN   A 1 134 ? 68.874 -10.130 32.013 1.00 34.44  ?  826  ASN   A C    1 
ATOM   2106 O  O    . ASN   A 1 134 ? 69.219 -10.310 33.181 1.00 38.62  ?  826  ASN   A O    1 
ATOM   2107 C  CB   . ASN   A 1 134 ? 70.083 -11.433 30.298 1.00 18.52  ?  826  ASN   A CB   1 
ATOM   2108 C  CG   . ASN   A 1 134 ? 71.250 -11.797 31.190 1.00 25.77  ?  826  ASN   A CG   1 
ATOM   2109 O  OD1  . ASN   A 1 134 ? 71.322 -12.892 31.738 1.00 31.22  ?  826  ASN   A OD1  1 
ATOM   2110 N  ND2  . ASN   A 1 134 ? 72.175 -10.880 31.352 1.00 21.00  ?  826  ASN   A ND2  1 
ATOM   2111 H  H    . ASN   A 1 134 ? 67.810 -11.085 29.125 1.00 23.60  ?  826  ASN   A H    1 
ATOM   2112 H  HA   . ASN   A 1 134 ? 68.604 -12.208 31.636 1.00 30.49  ?  826  ASN   A HA   1 
ATOM   2113 H  HB2  . ASN   A 1 134 ? 69.996 -12.232 29.564 1.00 20.52  ?  826  ASN   A HB2  1 
ATOM   2114 H  HB3  . ASN   A 1 134 ? 70.296 -10.526 29.728 1.00 20.52  ?  826  ASN   A HB3  1 
ATOM   2115 H  HD21 . ASN   A 1 134 ? 72.087 -9.985  30.898 1.00 23.00  ?  826  ASN   A HD21 1 
ATOM   2116 H  HD22 . ASN   A 1 134 ? 72.965 -11.070 31.949 1.00 23.00  ?  826  ASN   A HD22 1 
ATOM   2117 N  N    . TYR   A 1 135 ? 68.546 -8.937  31.524 1.00 30.36  ?  827  TYR   A N    1 
ATOM   2118 C  CA   . TYR   A 1 135 ? 68.460 -7.792  32.411 1.00 35.19  ?  827  TYR   A CA   1 
ATOM   2119 C  C    . TYR   A 1 135 ? 67.384 -7.961  33.477 1.00 36.90  ?  827  TYR   A C    1 
ATOM   2120 O  O    . TYR   A 1 135 ? 67.643 -7.704  34.652 1.00 31.96  ?  827  TYR   A O    1 
ATOM   2121 C  CB   . TYR   A 1 135 ? 68.249 -6.505  31.632 1.00 25.84  ?  827  TYR   A CB   1 
ATOM   2122 C  CG   . TYR   A 1 135 ? 67.981 -5.304  32.516 1.00 28.49  ?  827  TYR   A CG   1 
ATOM   2123 C  CD1  . TYR   A 1 135 ? 69.054 -4.597  33.091 1.00 25.37  ?  827  TYR   A CD1  1 
ATOM   2124 C  CD2  . TYR   A 1 135 ? 66.653 -4.908  32.778 1.00 14.69  ?  827  TYR   A CD2  1 
ATOM   2125 C  CE1  . TYR   A 1 135 ? 68.798 -3.485  33.915 1.00 36.96  ?  827  TYR   A CE1  1 
ATOM   2126 C  CE2  . TYR   A 1 135 ? 66.400 -3.800  33.602 1.00 30.85  ?  827  TYR   A CE2  1 
ATOM   2127 C  CZ   . TYR   A 1 135 ? 67.471 -3.088  34.170 1.00 26.54  ?  827  TYR   A CZ   1 
ATOM   2128 O  OH   . TYR   A 1 135 ? 67.222 -2.016  34.975 1.00 39.49  ?  827  TYR   A OH   1 
ATOM   2129 H  H    . TYR   A 1 135 ? 68.302 -8.839  30.544 1.00 32.36  ?  827  TYR   A H    1 
ATOM   2130 H  HA   . TYR   A 1 135 ? 69.414 -7.701  32.937 1.00 37.19  ?  827  TYR   A HA   1 
ATOM   2131 H  HB2  . TYR   A 1 135 ? 69.127 -6.305  31.017 1.00 27.84  ?  827  TYR   A HB2  1 
ATOM   2132 H  HB3  . TYR   A 1 135 ? 67.419 -6.611  30.934 1.00 27.84  ?  827  TYR   A HB3  1 
ATOM   2133 H  HD1  . TYR   A 1 135 ? 70.072 -4.906  32.903 1.00 27.37  ?  827  TYR   A HD1  1 
ATOM   2134 H  HD2  . TYR   A 1 135 ? 65.829 -5.458  32.348 1.00 16.69  ?  827  TYR   A HD2  1 
ATOM   2135 H  HE1  . TYR   A 1 135 ? 69.620 -2.940  34.353 1.00 38.96  ?  827  TYR   A HE1  1 
ATOM   2136 H  HE2  . TYR   A 1 135 ? 65.384 -3.499  33.800 1.00 32.85  ?  827  TYR   A HE2  1 
ATOM   2137 H  HH   . TYR   A 1 135 ? 68.014 -1.565  35.241 1.00 41.49  ?  827  TYR   A HH   1 
ATOM   2138 N  N    . LEU   A 1 136 ? 66.198 -8.423  33.083 1.00 28.79  ?  828  LEU   A N    1 
ATOM   2139 C  CA   . LEU   A 1 136 ? 65.147 -8.679  34.065 1.00 31.49  ?  828  LEU   A CA   1 
ATOM   2140 C  C    . LEU   A 1 136 ? 65.557 -9.706  35.112 1.00 46.44  ?  828  LEU   A C    1 
ATOM   2141 O  O    . LEU   A 1 136 ? 65.309 -9.503  36.301 1.00 50.30  ?  828  LEU   A O    1 
ATOM   2142 C  CB   . LEU   A 1 136 ? 63.821 -9.087  33.414 1.00 30.09  ?  828  LEU   A CB   1 
ATOM   2143 C  CG   . LEU   A 1 136 ? 63.173 -8.056  32.493 1.00 27.02  ?  828  LEU   A CG   1 
ATOM   2144 C  CD1  . LEU   A 1 136 ? 61.909 -8.623  31.876 1.00 29.44  ?  828  LEU   A CD1  1 
ATOM   2145 C  CD2  . LEU   A 1 136 ? 62.876 -6.734  33.177 1.00 30.70  ?  828  LEU   A CD2  1 
ATOM   2146 H  H    . LEU   A 1 136 ? 66.037 -8.630  32.103 1.00 30.79  ?  828  LEU   A H    1 
ATOM   2147 H  HA   . LEU   A 1 136 ? 64.983 -7.753  34.618 1.00 33.49  ?  828  LEU   A HA   1 
ATOM   2148 H  HB2  . LEU   A 1 136 ? 63.980 -10.009 32.853 1.00 32.09  ?  828  LEU   A HB2  1 
ATOM   2149 H  HB3  . LEU   A 1 136 ? 63.106 -9.352  34.194 1.00 32.09  ?  828  LEU   A HB3  1 
ATOM   2150 H  HG   . LEU   A 1 136 ? 63.858 -7.842  31.676 1.00 29.02  ?  828  LEU   A HG   1 
ATOM   2151 H  HD11 . LEU   A 1 136 ? 61.464 -7.924  31.166 1.00 31.44  ?  828  LEU   A HD11 1 
ATOM   2152 H  HD12 . LEU   A 1 136 ? 62.121 -9.539  31.326 1.00 31.44  ?  828  LEU   A HD12 1 
ATOM   2153 H  HD13 . LEU   A 1 136 ? 61.160 -8.860  32.632 1.00 31.44  ?  828  LEU   A HD13 1 
ATOM   2154 H  HD21 . LEU   A 1 136 ? 62.390 -6.042  32.491 1.00 32.70  ?  828  LEU   A HD21 1 
ATOM   2155 H  HD22 . LEU   A 1 136 ? 62.208 -6.873  34.027 1.00 32.70  ?  828  LEU   A HD22 1 
ATOM   2156 H  HD23 . LEU   A 1 136 ? 63.778 -6.237  33.533 1.00 32.70  ?  828  LEU   A HD23 1 
ATOM   2157 N  N    . GLU   A 1 137 ? 66.257 -10.749 34.675 1.00 46.66  ?  829  GLU   A N    1 
ATOM   2158 C  CA   . GLU   A 1 137 ? 66.853 -11.711 35.590 1.00 47.14  ?  829  GLU   A CA   1 
ATOM   2159 C  C    . GLU   A 1 137 ? 67.837 -11.108 36.591 1.00 39.78  ?  829  GLU   A C    1 
ATOM   2160 O  O    . GLU   A 1 137 ? 67.732 -11.358 37.794 1.00 46.23  ?  829  GLU   A O    1 
ATOM   2161 C  CB   . GLU   A 1 137 ? 67.417 -12.908 34.830 1.00 42.72  ?  829  GLU   A CB   1 
ATOM   2162 C  CG   . GLU   A 1 137 ? 68.198 -13.918 35.687 1.00 48.28  ?  829  GLU   A CG   1 
ATOM   2163 C  CD   . GLU   A 1 137 ? 68.313 -15.244 34.964 1.00 52.84  ?  829  GLU   A CD   1 
ATOM   2164 O  OE1  . GLU   A 1 137 ? 68.436 -15.251 33.722 1.00 61.46  ?  829  GLU   A OE1  1 
ATOM   2165 O  OE2  . GLU   A 1 137 ? 68.284 -16.296 35.631 1.00 57.69  -1 829  GLU   A OE2  1 
ATOM   2166 H  H    . GLU   A 1 137 ? 66.405 -10.861 33.676 1.00 48.66  ?  829  GLU   A H    1 
ATOM   2167 H  HA   . GLU   A 1 137 ? 66.033 -12.093 36.193 1.00 49.14  ?  829  GLU   A HA   1 
ATOM   2168 H  HB2  . GLU   A 1 137 ? 66.583 -13.405 34.330 1.00 44.72  ?  829  GLU   A HB2  1 
ATOM   2169 H  HB3  . GLU   A 1 137 ? 68.074 -12.555 34.035 1.00 44.72  ?  829  GLU   A HB3  1 
ATOM   2170 H  HG2  . GLU   A 1 137 ? 69.196 -13.542 35.917 1.00 50.28  ?  829  GLU   A HG2  1 
ATOM   2171 H  HG3  . GLU   A 1 137 ? 67.686 -14.085 36.636 1.00 50.28  ?  829  GLU   A HG3  1 
ATOM   2172 N  N    . ASP   A 1 138 ? 68.731 -10.247 36.114 1.00 30.80  ?  830  ASP   A N    1 
ATOM   2173 C  CA   . ASP   A 1 138 ? 69.619 -9.498  37.008 1.00 36.16  ?  830  ASP   A CA   1 
ATOM   2174 C  C    . ASP   A 1 138 ? 68.895 -8.624  38.031 1.00 38.49  ?  830  ASP   A C    1 
ATOM   2175 O  O    . ASP   A 1 138 ? 69.324 -8.486  39.174 1.00 49.83  ?  830  ASP   A O    1 
ATOM   2176 C  CB   . ASP   A 1 138 ? 70.600 -8.607  36.244 1.00 39.52  ?  830  ASP   A CB   1 
ATOM   2177 C  CG   . ASP   A 1 138 ? 71.636 -9.345  35.424 1.00 47.45  ?  830  ASP   A CG   1 
ATOM   2178 O  OD1  . ASP   A 1 138 ? 71.808 -10.566 35.616 1.00 60.81  ?  830  ASP   A OD1  1 
ATOM   2179 O  OD2  . ASP   A 1 138 ? 72.298 -8.704  34.581 1.00 52.57  -1 830  ASP   A OD2  1 
ATOM   2180 H  H    . ASP   A 1 138 ? 68.817 -10.120 35.109 1.00 32.80  ?  830  ASP   A H    1 
ATOM   2181 H  HA   . ASP   A 1 138 ? 70.190 -10.226 37.590 1.00 38.16  ?  830  ASP   A HA   1 
ATOM   2182 H  HB2  . ASP   A 1 138 ? 70.063 -7.924  35.587 1.00 41.52  ?  830  ASP   A HB2  1 
ATOM   2183 H  HB3  . ASP   A 1 138 ? 71.156 -7.980  36.942 1.00 41.52  ?  830  ASP   A HB3  1 
ATOM   2184 N  N    . ARG   A 1 139 ? 67.764 -8.067  37.627 1.00 34.32  ?  831  ARG   A N    1 
ATOM   2185 C  CA   . ARG   A 1 139 ? 66.923 -7.276  38.520 1.00 38.07  ?  831  ARG   A CA   1 
ATOM   2186 C  C    . ARG   A 1 139 ? 65.990 -8.132  39.369 1.00 41.81  ?  831  ARG   A C    1 
ATOM   2187 O  O    . ARG   A 1 139 ? 65.153 -7.595  40.096 1.00 43.60  ?  831  ARG   A O    1 
ATOM   2188 C  CB   . ARG   A 1 139 ? 66.077 -6.292  37.700 1.00 31.71  ?  831  ARG   A CB   1 
ATOM   2189 C  CG   . ARG   A 1 139 ? 66.896 -5.322  36.848 1.00 35.18  ?  831  ARG   A CG   1 
ATOM   2190 C  CD   . ARG   A 1 139 ? 67.688 -4.279  37.626 1.00 40.89  ?  831  ARG   A CD   1 
ATOM   2191 N  NE   . ARG   A 1 139 ? 66.821 -3.142  37.993 1.00 72.57  ?  831  ARG   A NE   1 
ATOM   2192 C  CZ   . ARG   A 1 139 ? 66.312 -2.952  39.224 1.00 68.98  ?  831  ARG   A CZ   1 
ATOM   2193 N  NH1  . ARG   A 1 139 ? 66.593 -3.805  40.215 1.00 89.93  ?  831  ARG   A NH1  1 
ATOM   2194 N  NH2  . ARG   A 1 139 ? 65.516 -1.907  39.458 1.00 93.43  1  831  ARG   A NH2  1 
ATOM   2195 H  H    . ARG   A 1 139 ? 67.471 -8.225  36.667 1.00 36.32  ?  831  ARG   A H    1 
ATOM   2196 H  HA   . ARG   A 1 139 ? 67.542 -6.714  39.220 1.00 40.07  ?  831  ARG   A HA   1 
ATOM   2197 H  HB2  . ARG   A 1 139 ? 65.412 -6.855  37.042 1.00 33.71  ?  831  ARG   A HB2  1 
ATOM   2198 H  HB3  . ARG   A 1 139 ? 65.418 -5.714  38.351 1.00 33.71  ?  831  ARG   A HB3  1 
ATOM   2199 H  HG2  . ARG   A 1 139 ? 67.588 -5.854  36.201 1.00 37.18  ?  831  ARG   A HG2  1 
ATOM   2200 H  HG3  . ARG   A 1 139 ? 66.210 -4.815  36.170 1.00 37.18  ?  831  ARG   A HG3  1 
ATOM   2201 H  HD2  . ARG   A 1 139 ? 68.235 -4.697  38.469 1.00 42.89  ?  831  ARG   A HD2  1 
ATOM   2202 H  HD3  . ARG   A 1 139 ? 68.453 -3.872  36.964 1.00 42.89  ?  831  ARG   A HD3  1 
ATOM   2203 H  HE   . ARG   A 1 139 ? 66.590 -2.485  37.258 1.00 74.57  ?  831  ARG   A HE   1 
ATOM   2204 H  HH11 . ARG   A 1 139 ? 67.194 -4.596  40.047 1.00 91.93  ?  831  ARG   A HH11 1 
ATOM   2205 H  HH12 . ARG   A 1 139 ? 66.193 -3.666  41.132 1.00 91.93  ?  831  ARG   A HH12 1 
ATOM   2206 H  HH21 . ARG   A 1 139 ? 65.286 -1.260  38.709 1.00 95.43  ?  831  ARG   A HH21 1 
ATOM   2207 H  HH22 . ARG   A 1 139 ? 65.120 -1.768  40.377 1.00 95.43  ?  831  ARG   A HH22 1 
ATOM   2208 N  N    . ARG   A 1 140 ? 66.108 -9.453  39.254 1.00 48.05  ?  832  ARG   A N    1 
ATOM   2209 C  CA   . ARG   A 1 140 ? 65.307 -10.406 40.005 1.00 37.42  ?  832  ARG   A CA   1 
ATOM   2210 C  C    . ARG   A 1 140 ? 63.844 -10.433 39.582 1.00 38.81  ?  832  ARG   A C    1 
ATOM   2211 O  O    . ARG   A 1 140 ? 62.996 -10.890 40.343 1.00 40.13  ?  832  ARG   A O    1 
ATOM   2212 C  CB   . ARG   A 1 140 ? 65.501 -10.320 41.527 1.00 53.98  ?  832  ARG   A CB   1 
ATOM   2213 C  CG   . ARG   A 1 140 ? 66.937 -10.509 42.022 1.00 40.55  ?  832  ARG   A CG   1 
ATOM   2214 C  CD   . ARG   A 1 140 ? 67.050 -10.237 43.520 1.00 67.62  ?  832  ARG   A CD   1 
ATOM   2215 N  NE   . ARG   A 1 140 ? 68.276 -10.814 44.097 1.00 89.34  ?  832  ARG   A NE   1 
ATOM   2216 C  CZ   . ARG   A 1 140 ? 68.583 -10.761 45.410 1.00 103.38 ?  832  ARG   A CZ   1 
ATOM   2217 N  NH1  . ARG   A 1 140 ? 67.767 -10.146 46.277 1.00 108.73 ?  832  ARG   A NH1  1 
ATOM   2218 N  NH2  . ARG   A 1 140 ? 69.714 -11.325 45.850 1.00 102.48 1  832  ARG   A NH2  1 
ATOM   2219 H  H    . ARG   A 1 140 ? 66.792 -9.833  38.606 1.00 50.05  ?  832  ARG   A H    1 
ATOM   2220 H  HA   . ARG   A 1 140 ? 65.687 -11.383 39.704 1.00 39.42  ?  832  ARG   A HA   1 
ATOM   2221 H  HB2  . ARG   A 1 140 ? 65.132 -9.363  41.890 1.00 55.98  ?  832  ARG   A HB2  1 
ATOM   2222 H  HB3  . ARG   A 1 140 ? 64.878 -11.070 42.019 1.00 55.98  ?  832  ARG   A HB3  1 
ATOM   2223 H  HG2  . ARG   A 1 140 ? 67.271 -11.521 41.789 1.00 42.55  ?  832  ARG   A HG2  1 
ATOM   2224 H  HG3  . ARG   A 1 140 ? 67.609 -9.833  41.491 1.00 42.55  ?  832  ARG   A HG3  1 
ATOM   2225 H  HD2  . ARG   A 1 140 ? 67.024 -9.163  43.710 1.00 69.62  ?  832  ARG   A HD2  1 
ATOM   2226 H  HD3  . ARG   A 1 140 ? 66.199 -10.676 44.044 1.00 69.62  ?  832  ARG   A HD3  1 
ATOM   2227 H  HE   . ARG   A 1 140 ? 68.911 -11.277 43.462 1.00 91.34  ?  832  ARG   A HE   1 
ATOM   2228 H  HH11 . ARG   A 1 140 ? 66.922 -9.682  45.948 1.00 110.73 ?  832  ARG   A HH11 1 
ATOM   2229 H  HH12 . ARG   A 1 140 ? 68.000 -10.115 47.260 1.00 110.73 ?  832  ARG   A HH12 1 
ATOM   2230 H  HH21 . ARG   A 1 140 ? 70.335 -11.787 45.203 1.00 104.48 ?  832  ARG   A HH21 1 
ATOM   2231 H  HH22 . ARG   A 1 140 ? 69.951 -11.288 46.830 1.00 104.48 ?  832  ARG   A HH22 1 
ATOM   2232 N  N    . LEU   A 1 141 ? 63.528 -9.943  38.388 1.00 42.23  ?  833  LEU   A N    1 
ATOM   2233 C  CA   . LEU   A 1 141 ? 62.151 -9.927  37.911 1.00 44.71  ?  833  LEU   A CA   1 
ATOM   2234 C  C    . LEU   A 1 141 ? 61.890 -11.138 37.033 1.00 47.44  ?  833  LEU   A C    1 
ATOM   2235 O  O    . LEU   A 1 141 ? 62.637 -11.435 36.096 1.00 48.27  ?  833  LEU   A O    1 
ATOM   2236 C  CB   . LEU   A 1 141 ? 61.883 -8.689  37.049 1.00 47.04  ?  833  LEU   A CB   1 
ATOM   2237 C  CG   . LEU   A 1 141 ? 61.731 -7.380  37.816 1.00 58.10  ?  833  LEU   A CG   1 
ATOM   2238 C  CD1  . LEU   A 1 141 ? 61.699 -6.203  36.854 1.00 57.95  ?  833  LEU   A CD1  1 
ATOM   2239 C  CD2  . LEU   A 1 141 ? 60.485 -7.371  38.692 1.00 58.36  ?  833  LEU   A CD2  1 
ATOM   2240 H  H    . LEU   A 1 141 ? 64.270 -9.675  37.742 1.00 44.23  ?  833  LEU   A H    1 
ATOM   2241 H  HA   . LEU   A 1 141 ? 61.443 -9.937  38.739 1.00 46.71  ?  833  LEU   A HA   1 
ATOM   2242 H  HB2  . LEU   A 1 141 ? 62.695 -8.585  36.330 1.00 49.04  ?  833  LEU   A HB2  1 
ATOM   2243 H  HB3  . LEU   A 1 141 ? 60.982 -8.836  36.449 1.00 49.04  ?  833  LEU   A HB3  1 
ATOM   2244 H  HG   . LEU   A 1 141 ? 62.603 -7.249  38.460 1.00 60.10  ?  833  LEU   A HG   1 
ATOM   2245 H  HD11 . LEU   A 1 141 ? 61.595 -5.256  37.386 1.00 59.95  ?  833  LEU   A HD11 1 
ATOM   2246 H  HD12 . LEU   A 1 141 ? 62.618 -6.142  36.271 1.00 59.95  ?  833  LEU   A HD12 1 
ATOM   2247 H  HD13 . LEU   A 1 141 ? 60.864 -6.282  36.155 1.00 59.95  ?  833  LEU   A HD13 1 
ATOM   2248 H  HD21 . LEU   A 1 141 ? 60.309 -6.384  39.119 1.00 60.36  ?  833  LEU   A HD21 1 
ATOM   2249 H  HD22 . LEU   A 1 141 ? 59.592 -7.652  38.131 1.00 60.36  ?  833  LEU   A HD22 1 
ATOM   2250 H  HD23 . LEU   A 1 141 ? 60.580 -8.055  39.533 1.00 60.36  ?  833  LEU   A HD23 1 
ATOM   2251 N  N    . VAL   A 1 142 ? 60.788 -11.803 37.327 1.00 39.82  ?  834  VAL   A N    1 
ATOM   2252 C  CA   . VAL   A 1 142 ? 60.237 -12.849 36.493 1.00 26.48  ?  834  VAL   A CA   1 
ATOM   2253 C  C    . VAL   A 1 142 ? 59.079 -12.195 35.760 1.00 37.89  ?  834  VAL   A C    1 
ATOM   2254 O  O    . VAL   A 1 142 ? 58.212 -11.584 36.388 1.00 46.80  ?  834  VAL   A O    1 
ATOM   2255 C  CB   . VAL   A 1 142 ? 59.776 -14.028 37.375 1.00 40.66  ?  834  VAL   A CB   1 
ATOM   2256 C  CG1  . VAL   A 1 142 ? 59.221 -15.190 36.574 1.00 41.93  ?  834  VAL   A CG1  1 
ATOM   2257 C  CG2  . VAL   A 1 142 ? 60.904 -14.570 38.256 1.00 31.33  ?  834  VAL   A CG2  1 
ATOM   2258 H  H    . VAL   A 1 142 ? 60.199 -11.477 38.094 1.00 41.82  ?  834  VAL   A H    1 
ATOM   2259 H  HA   . VAL   A 1 142 ? 60.971 -13.224 35.780 1.00 28.48  ?  834  VAL   A HA   1 
ATOM   2260 H  HB   . VAL   A 1 142 ? 58.991 -13.672 38.046 1.00 42.66  ?  834  VAL   A HB   1 
ATOM   2261 H  HG11 . VAL   A 1 142 ? 58.951 -16.022 37.224 1.00 43.93  ?  834  VAL   A HG11 1 
ATOM   2262 H  HG12 . VAL   A 1 142 ? 58.340 -14.920 36.005 1.00 43.93  ?  834  VAL   A HG12 1 
ATOM   2263 H  HG13 . VAL   A 1 142 ? 59.953 -15.553 35.855 1.00 43.93  ?  834  VAL   A HG13 1 
ATOM   2264 H  HG21 . VAL   A 1 142 ? 60.549 -15.351 38.929 1.00 33.33  ?  834  VAL   A HG21 1 
ATOM   2265 H  HG22 . VAL   A 1 142 ? 61.711 -14.988 37.654 1.00 33.33  ?  834  VAL   A HG22 1 
ATOM   2266 H  HG23 . VAL   A 1 142 ? 61.338 -13.791 38.881 1.00 33.33  ?  834  VAL   A HG23 1 
ATOM   2267 N  N    . HIS   A 1 143 ? 59.088 -12.294 34.433 1.00 44.58  ?  835  HIS   A N    1 
ATOM   2268 C  CA   . HIS   A 1 143 ? 58.184 -11.503 33.602 1.00 30.91  ?  835  HIS   A CA   1 
ATOM   2269 C  C    . HIS   A 1 143 ? 56.790 -12.114 33.547 1.00 40.15  ?  835  HIS   A C    1 
ATOM   2270 O  O    . HIS   A 1 143 ? 55.791 -11.421 33.747 1.00 33.67  ?  835  HIS   A O    1 
ATOM   2271 C  CB   . HIS   A 1 143 ? 58.750 -11.360 32.182 1.00 29.00  ?  835  HIS   A CB   1 
ATOM   2272 C  CG   . HIS   A 1 143 ? 57.928 -10.516 31.232 1.00 16.21  ?  835  HIS   A CG   1 
ATOM   2273 N  ND1  . HIS   A 1 143 ? 56.710 -10.955 30.681 1.00 15.29  ?  835  HIS   A ND1  1 
ATOM   2274 C  CD2  . HIS   A 1 143 ? 58.178 -9.222  30.745 1.00 24.46  ?  835  HIS   A CD2  1 
ATOM   2275 C  CE1  . HIS   A 1 143 ? 56.295 -9.962  29.932 1.00 18.27  ?  835  HIS   A CE1  1 
ATOM   2276 N  NE2  . HIS   A 1 143 ? 57.096 -8.928  29.921 1.00 23.90  ?  835  HIS   A NE2  1 
ATOM   2277 H  H    . HIS   A 1 143 ? 59.760 -12.906 33.984 1.00 46.58  ?  835  HIS   A H    1 
ATOM   2278 H  HA   . HIS   A 1 143 ? 58.090 -10.499 34.023 1.00 32.91  ?  835  HIS   A HA   1 
ATOM   2279 H  HB2  . HIS   A 1 143 ? 59.743 -10.912 32.237 1.00 31.00  ?  835  HIS   A HB2  1 
ATOM   2280 H  HB3  . HIS   A 1 143 ? 58.883 -12.338 31.719 1.00 31.00  ?  835  HIS   A HB3  1 
ATOM   2281 H  HD2  . HIS   A 1 143 ? 58.990 -8.530  30.916 1.00 26.46  ?  835  HIS   A HD2  1 
ATOM   2282 H  HE1  . HIS   A 1 143 ? 55.369 -9.990  29.374 1.00 20.27  ?  835  HIS   A HE1  1 
ATOM   2283 H  HE2  . HIS   A 1 143 ? 56.935 -8.058  29.404 1.00 25.90  ?  835  HIS   A HE2  1 
ATOM   2284 N  N    . ARG   A 1 144 ? 56.722 -13.414 33.266 1.00 38.26  ?  836  ARG   A N    1 
ATOM   2285 C  CA   . ARG   A 1 144 ? 55.476 -14.183 33.364 1.00 30.49  ?  836  ARG   A CA   1 
ATOM   2286 C  C    . ARG   A 1 144 ? 54.516 -14.066 32.189 1.00 28.34  ?  836  ARG   A C    1 
ATOM   2287 O  O    . ARG   A 1 144 ? 53.471 -14.725 32.195 1.00 31.25  ?  836  ARG   A O    1 
ATOM   2288 C  CB   . ARG   A 1 144 ? 54.772 -14.116 34.731 1.00 43.98  ?  836  ARG   A CB   1 
ATOM   2289 C  CG   . ARG   A 1 144 ? 55.698 -14.433 35.905 1.00 51.21  ?  836  ARG   A CG   1 
ATOM   2290 C  CD   . ARG   A 1 144 ? 55.082 -14.320 37.288 1.00 60.13  ?  836  ARG   A CD   1 
ATOM   2291 N  NE   . ARG   A 1 144 ? 53.943 -15.239 37.476 1.00 68.02  ?  836  ARG   A NE   1 
ATOM   2292 C  CZ   . ARG   A 1 144 ? 52.660 -14.840 37.519 1.00 71.65  ?  836  ARG   A CZ   1 
ATOM   2293 N  NH1  . ARG   A 1 144 ? 52.348 -13.554 37.366 1.00 58.07  ?  836  ARG   A NH1  1 
ATOM   2294 N  NH2  . ARG   A 1 144 ? 51.688 -15.735 37.718 1.00 79.95  1  836  ARG   A NH2  1 
ATOM   2295 H  H    . ARG   A 1 144 ? 57.570 -13.913 33.034 1.00 40.26  ?  836  ARG   A H    1 
ATOM   2296 H  HA   . ARG   A 1 144 ? 55.821 -15.212 33.274 1.00 32.49  ?  836  ARG   A HA   1 
ATOM   2297 H  HB2  . ARG   A 1 144 ? 54.326 -13.133 34.875 1.00 45.98  ?  836  ARG   A HB2  1 
ATOM   2298 H  HB3  . ARG   A 1 144 ? 53.937 -14.817 34.746 1.00 45.98  ?  836  ARG   A HB3  1 
ATOM   2299 H  HG2  . ARG   A 1 144 ? 56.119 -15.429 35.772 1.00 53.21  ?  836  ARG   A HG2  1 
ATOM   2300 H  HG3  . ARG   A 1 144 ? 56.529 -13.732 35.888 1.00 53.21  ?  836  ARG   A HG3  1 
ATOM   2301 H  HD2  . ARG   A 1 144 ? 55.836 -14.601 38.024 1.00 62.13  ?  836  ARG   A HD2  1 
ATOM   2302 H  HD3  . ARG   A 1 144 ? 54.836 -13.289 37.529 1.00 62.13  ?  836  ARG   A HD3  1 
ATOM   2303 H  HE   . ARG   A 1 144 ? 54.159 -16.222 37.594 1.00 70.02  ?  836  ARG   A HE   1 
ATOM   2304 H  HH11 . ARG   A 1 144 ? 53.077 -12.861 37.209 1.00 60.07  ?  836  ARG   A HH11 1 
ATOM   2305 H  HH12 . ARG   A 1 144 ? 51.378 -13.259 37.421 1.00 60.07  ?  836  ARG   A HH12 1 
ATOM   2306 H  HH21 . ARG   A 1 144 ? 51.914 -16.713 37.837 1.00 81.95  ?  836  ARG   A HH21 1 
ATOM   2307 H  HH22 . ARG   A 1 144 ? 50.723 -15.431 37.762 1.00 81.95  ?  836  ARG   A HH22 1 
ATOM   2308 N  N    . ASP   A 1 145 ? 54.842 -13.239 31.200 1.00 27.50  ?  837  ASP   A N    1 
ATOM   2309 C  CA   . ASP   A 1 145 ? 54.007 -13.076 30.012 1.00 36.09  ?  837  ASP   A CA   1 
ATOM   2310 C  C    . ASP   A 1 145 ? 54.826 -12.746 28.765 1.00 38.37  ?  837  ASP   A C    1 
ATOM   2311 O  O    . ASP   A 1 145 ? 54.430 -11.921 27.931 1.00 35.53  ?  837  ASP   A O    1 
ATOM   2312 C  CB   . ASP   A 1 145 ? 52.806 -12.149 30.268 1.00 35.17  ?  837  ASP   A CB   1 
ATOM   2313 C  CG   . ASP   A 1 145 ? 51.649 -12.308 29.292 1.00 52.29  ?  837  ASP   A CG   1 
ATOM   2314 O  OD1  . ASP   A 1 145 ? 51.497 -13.397 28.696 1.00 63.61  ?  837  ASP   A OD1  1 
ATOM   2315 O  OD2  . ASP   A 1 145 ? 50.879 -11.343 29.111 1.00 57.53  -1 837  ASP   A OD2  1 
ATOM   2316 H  H    . ASP   A 1 145 ? 55.690 -12.681 31.246 1.00 29.50  ?  837  ASP   A H    1 
ATOM   2317 H  HA   . ASP   A 1 145 ? 53.620 -14.072 29.784 1.00 38.09  ?  837  ASP   A HA   1 
ATOM   2318 H  HB2  . ASP   A 1 145 ? 52.407 -12.326 31.263 1.00 37.17  ?  837  ASP   A HB2  1 
ATOM   2319 H  HB3  . ASP   A 1 145 ? 53.136 -11.109 30.262 1.00 37.17  ?  837  ASP   A HB3  1 
ATOM   2320 N  N    . LEU   A 1 146 ? 56.015 -13.336 28.654 1.00 35.68  ?  838  LEU   A N    1 
ATOM   2321 C  CA   . LEU   A 1 146 ? 56.837 -13.101 27.471 1.00 27.09  ?  838  LEU   A CA   1 
ATOM   2322 C  C    . LEU   A 1 146 ? 56.217 -13.809 26.271 1.00 29.48  ?  838  LEU   A C    1 
ATOM   2323 O  O    . LEU   A 1 146 ? 55.862 -14.988 26.323 1.00 29.47  ?  838  LEU   A O    1 
ATOM   2324 C  CB   . LEU   A 1 146 ? 58.268 -13.577 27.699 1.00 33.63  ?  838  LEU   A CB   1 
ATOM   2325 C  CG   . LEU   A 1 146 ? 59.232 -13.471 26.508 1.00 27.80  ?  838  LEU   A CG   1 
ATOM   2326 C  CD1  . LEU   A 1 146 ? 59.433 -12.039 26.040 1.00 20.79  ?  838  LEU   A CD1  1 
ATOM   2327 C  CD2  . LEU   A 1 146 ? 60.563 -14.105 26.864 1.00 23.65  ?  838  LEU   A CD2  1 
ATOM   2328 H  H    . LEU   A 1 146 ? 56.302 -14.038 29.336 1.00 37.68  ?  838  LEU   A H    1 
ATOM   2329 H  HA   . LEU   A 1 146 ? 56.874 -12.024 27.289 1.00 29.09  ?  838  LEU   A HA   1 
ATOM   2330 H  HB2  . LEU   A 1 146 ? 58.684 -13.024 28.543 1.00 35.63  ?  838  LEU   A HB2  1 
ATOM   2331 H  HB3  . LEU   A 1 146 ? 58.234 -14.616 28.021 1.00 35.63  ?  838  LEU   A HB3  1 
ATOM   2332 H  HG   . LEU   A 1 146 ? 58.839 -14.044 25.668 1.00 29.80  ?  838  LEU   A HG   1 
ATOM   2333 H  HD11 . LEU   A 1 146 ? 60.147 -11.992 25.217 1.00 22.79  ?  838  LEU   A HD11 1 
ATOM   2334 H  HD12 . LEU   A 1 146 ? 58.509 -11.592 25.674 1.00 22.79  ?  838  LEU   A HD12 1 
ATOM   2335 H  HD13 . LEU   A 1 146 ? 59.813 -11.405 26.843 1.00 22.79  ?  838  LEU   A HD13 1 
ATOM   2336 H  HD21 . LEU   A 1 146 ? 61.273 -14.037 26.040 1.00 25.65  ?  838  LEU   A HD21 1 
ATOM   2337 H  HD22 . LEU   A 1 146 ? 61.003 -13.629 27.735 1.00 25.65  ?  838  LEU   A HD22 1 
ATOM   2338 H  HD23 . LEU   A 1 146 ? 60.436 -15.157 27.114 1.00 25.65  ?  838  LEU   A HD23 1 
ATOM   2339 N  N    . ALA   A 1 147 ? 56.073 -13.056 25.199 1.00 24.87  ?  839  ALA   A N    1 
ATOM   2340 C  CA   . ALA   A 1 147 ? 55.373 -13.509 24.015 1.00 31.41  ?  839  ALA   A CA   1 
ATOM   2341 C  C    . ALA   A 1 147 ? 55.664 -12.483 22.948 1.00 35.10  ?  839  ALA   A C    1 
ATOM   2342 O  O    . ALA   A 1 147 ? 55.962 -11.328 23.272 1.00 30.49  ?  839  ALA   A O    1 
ATOM   2343 C  CB   . ALA   A 1 147 ? 53.878 -13.661 24.263 1.00 33.40  ?  839  ALA   A CB   1 
ATOM   2344 H  H    . ALA   A 1 147 ? 56.413 -12.105 25.178 1.00 26.87  ?  839  ALA   A H    1 
ATOM   2345 H  HA   . ALA   A 1 147 ? 55.770 -14.473 23.697 1.00 33.41  ?  839  ALA   A HA   1 
ATOM   2346 H  HB1  . ALA   A 1 147 ? 53.360 -13.984 23.368 1.00 35.40  ?  839  ALA   A HB1  1 
ATOM   2347 H  HB2  . ALA   A 1 147 ? 53.675 -14.417 25.021 1.00 35.40  ?  839  ALA   A HB2  1 
ATOM   2348 H  HB3  . ALA   A 1 147 ? 53.435 -12.729 24.613 1.00 35.40  ?  839  ALA   A HB3  1 
ATOM   2349 N  N    . ALA   A 1 148 ? 55.534 -12.851 21.677 1.00 33.98  ?  840  ALA   A N    1 
ATOM   2350 C  CA   . ALA   A 1 148 ? 55.884 -11.898 20.617 1.00 31.54  ?  840  ALA   A CA   1 
ATOM   2351 C  C    . ALA   A 1 148 ? 54.962 -10.686 20.532 1.00 28.26  ?  840  ALA   A C    1 
ATOM   2352 O  O    . ALA   A 1 148 ? 55.372 -9.622  20.063 1.00 39.68  ?  840  ALA   A O    1 
ATOM   2353 C  CB   . ALA   A 1 148 ? 55.941 -12.588 19.261 1.00 27.25  ?  840  ALA   A CB   1 
ATOM   2354 H  H    . ALA   A 1 148 ? 55.298 -13.806 21.437 1.00 35.98  ?  840  ALA   A H    1 
ATOM   2355 H  HA   . ALA   A 1 148 ? 56.886 -11.514 20.825 1.00 33.54  ?  840  ALA   A HA   1 
ATOM   2356 H  HB1  . ALA   A 1 148 ? 56.263 -11.898 18.479 1.00 29.25  ?  840  ALA   A HB1  1 
ATOM   2357 H  HB2  . ALA   A 1 148 ? 56.648 -13.418 19.268 1.00 29.25  ?  840  ALA   A HB2  1 
ATOM   2358 H  HB3  . ALA   A 1 148 ? 54.968 -12.987 18.971 1.00 29.25  ?  840  ALA   A HB3  1 
ATOM   2359 N  N    . ARG   A 1 149 ? 53.724 -10.836 21.014 1.00 35.64  ?  841  ARG   A N    1 
ATOM   2360 C  CA   . ARG   A 1 149 ? 52.814 -9.695  21.210 1.00 39.17  ?  841  ARG   A CA   1 
ATOM   2361 C  C    . ARG   A 1 149 ? 53.356 -8.639  22.169 1.00 35.07  ?  841  ARG   A C    1 
ATOM   2362 O  O    . ARG   A 1 149 ? 53.061 -7.454  22.024 1.00 42.82  ?  841  ARG   A O    1 
ATOM   2363 C  CB   . ARG   A 1 149 ? 51.416 -10.157 21.680 1.00 24.28  ?  841  ARG   A CB   1 
ATOM   2364 C  CG   . ARG   A 1 149 ? 51.396 -10.790 23.078 1.00 27.48  ?  841  ARG   A CG   1 
ATOM   2365 C  CD   . ARG   A 1 149 ? 50.098 -11.474 23.506 1.00 28.50  ?  841  ARG   A CD   1 
ATOM   2366 N  NE   . ARG   A 1 149 ? 50.324 -12.213 24.776 1.00 44.24  ?  841  ARG   A NE   1 
ATOM   2367 C  CZ   . ARG   A 1 149 ? 50.467 -13.553 24.861 1.00 44.77  ?  841  ARG   A CZ   1 
ATOM   2368 N  NH1  . ARG   A 1 149 ? 50.378 -14.316 23.764 1.00 55.77  ?  841  ARG   A NH1  1 
ATOM   2369 N  NH2  . ARG   A 1 149 ? 50.709 -14.124 26.046 1.00 40.94  1  841  ARG   A NH2  1 
ATOM   2370 H  H    . ARG   A 1 149 ? 53.407 -11.769 21.269 1.00 37.64  ?  841  ARG   A H    1 
ATOM   2371 H  HA   . ARG   A 1 149 ? 52.691 -9.210  20.239 1.00 41.17  ?  841  ARG   A HA   1 
ATOM   2372 H  HB2  . ARG   A 1 149 ? 50.730 -9.308  21.665 1.00 26.28  ?  841  ARG   A HB2  1 
ATOM   2373 H  HB3  . ARG   A 1 149 ? 51.023 -10.869 20.954 1.00 26.28  ?  841  ARG   A HB3  1 
ATOM   2374 H  HG2  . ARG   A 1 149 ? 52.201 -11.521 23.139 1.00 29.48  ?  841  ARG   A HG2  1 
ATOM   2375 H  HG3  . ARG   A 1 149 ? 51.624 -10.032 23.820 1.00 29.48  ?  841  ARG   A HG3  1 
ATOM   2376 H  HD2  . ARG   A 1 149 ? 49.329 -10.721 23.679 1.00 30.50  ?  841  ARG   A HD2  1 
ATOM   2377 H  HD3  . ARG   A 1 149 ? 49.718 -12.123 22.718 1.00 30.50  ?  841  ARG   A HD3  1 
ATOM   2378 H  HE   . ARG   A 1 149 ? 50.395 -11.661 25.622 1.00 46.24  ?  841  ARG   A HE   1 
ATOM   2379 H  HH11 . ARG   A 1 149 ? 50.202 -13.891 22.865 1.00 57.77  ?  841  ARG   A HH11 1 
ATOM   2380 H  HH12 . ARG   A 1 149 ? 50.495 -15.319 23.829 1.00 57.77  ?  841  ARG   A HH12 1 
ATOM   2381 H  HH21 . ARG   A 1 149 ? 50.806 -13.556 26.889 1.00 42.94  ?  841  ARG   A HH21 1 
ATOM   2382 H  HH22 . ARG   A 1 149 ? 50.827 -15.123 26.111 1.00 42.94  ?  841  ARG   A HH22 1 
ATOM   2383 N  N    . ASN   A 1 150 ? 54.171 -9.090  23.120 1.00 33.93  ?  842  ASN   A N    1 
ATOM   2384 C  CA   . ASN   A 1 150 ? 54.701 -8.240  24.186 1.00 32.98  ?  842  ASN   A CA   1 
ATOM   2385 C  C    . ASN   A 1 150 ? 56.147 -7.842  23.942 1.00 32.03  ?  842  ASN   A C    1 
ATOM   2386 O  O    . ASN   A 1 150 ? 56.862 -7.432  24.864 1.00 33.87  ?  842  ASN   A O    1 
ATOM   2387 C  CB   . ASN   A 1 150 ? 54.550 -8.920  25.556 1.00 32.89  ?  842  ASN   A CB   1 
ATOM   2388 C  CG   . ASN   A 1 150 ? 53.100 -9.039  25.978 1.00 33.16  ?  842  ASN   A CG   1 
ATOM   2389 O  OD1  . ASN   A 1 150 ? 52.241 -8.277  25.546 1.00 27.48  ?  842  ASN   A OD1  1 
ATOM   2390 N  ND2  . ASN   A 1 150 ? 52.806 -10.004 26.820 1.00 28.67  ?  842  ASN   A ND2  1 
ATOM   2391 H  H    . ASN   A 1 150 ? 54.512 -10.044 23.080 1.00 35.93  ?  842  ASN   A H    1 
ATOM   2392 H  HA   . ASN   A 1 150 ? 54.165 -7.289  24.225 1.00 34.98  ?  842  ASN   A HA   1 
ATOM   2393 H  HB2  . ASN   A 1 150 ? 55.027 -9.901  25.550 1.00 34.89  ?  842  ASN   A HB2  1 
ATOM   2394 H  HB3  . ASN   A 1 150 ? 55.045 -8.340  26.336 1.00 34.89  ?  842  ASN   A HB3  1 
ATOM   2395 H  HD21 . ASN   A 1 150 ? 53.538 -10.631 27.167 1.00 30.67  ?  842  ASN   A HD21 1 
ATOM   2396 H  HD22 . ASN   A 1 150 ? 51.859 -10.113 27.150 1.00 30.67  ?  842  ASN   A HD22 1 
ATOM   2397 N  N    . VAL   A 1 151 ? 56.568 -7.916  22.684 1.00 28.52  ?  843  VAL   A N    1 
ATOM   2398 C  CA   . VAL   A 1 151 ? 57.813 -7.295  22.256 1.00 33.30  ?  843  VAL   A CA   1 
ATOM   2399 C  C    . VAL   A 1 151 ? 57.401 -6.235  21.251 1.00 31.93  ?  843  VAL   A C    1 
ATOM   2400 O  O    . VAL   A 1 151 ? 56.592 -6.494  20.355 1.00 35.46  ?  843  VAL   A O    1 
ATOM   2401 C  CB   . VAL   A 1 151 ? 58.801 -8.328  21.689 1.00 28.00  ?  843  VAL   A CB   1 
ATOM   2402 C  CG1  . VAL   A 1 151 ? 60.094 -7.689  21.214 1.00 20.07  ?  843  VAL   A CG1  1 
ATOM   2403 C  CG2  . VAL   A 1 151 ? 59.122 -9.439  22.683 1.00 26.42  ?  843  VAL   A CG2  1 
ATOM   2404 H  H    . VAL   A 1 151 ? 55.923 -8.216  21.963 1.00 30.52  ?  843  VAL   A H    1 
ATOM   2405 H  HA   . VAL   A 1 151 ? 58.312 -6.794  23.085 1.00 35.30  ?  843  VAL   A HA   1 
ATOM   2406 H  HB   . VAL   A 1 151 ? 58.331 -8.802  20.825 1.00 30.00  ?  843  VAL   A HB   1 
ATOM   2407 H  HG11 . VAL   A 1 151 ? 60.799 -8.437  20.853 1.00 22.07  ?  843  VAL   A HG11 1 
ATOM   2408 H  HG12 . VAL   A 1 151 ? 59.910 -7.011  20.382 1.00 22.07  ?  843  VAL   A HG12 1 
ATOM   2409 H  HG13 . VAL   A 1 151 ? 60.586 -7.127  22.009 1.00 22.07  ?  843  VAL   A HG13 1 
ATOM   2410 H  HG21 . VAL   A 1 151 ? 59.790 -10.181 22.247 1.00 28.42  ?  843  VAL   A HG21 1 
ATOM   2411 H  HG22 . VAL   A 1 151 ? 59.602 -9.044  23.579 1.00 28.42  ?  843  VAL   A HG22 1 
ATOM   2412 H  HG23 . VAL   A 1 151 ? 58.227 -9.973  23.001 1.00 28.42  ?  843  VAL   A HG23 1 
ATOM   2413 N  N    . LEU   A 1 152 ? 57.921 -5.033  21.430 1.00 29.70  ?  844  LEU   A N    1 
ATOM   2414 C  CA   . LEU   A 1 152 ? 57.559 -3.908  20.578 1.00 33.66  ?  844  LEU   A CA   1 
ATOM   2415 C  C    . LEU   A 1 152 ? 58.763 -3.477  19.774 1.00 29.96  ?  844  LEU   A C    1 
ATOM   2416 O  O    . LEU   A 1 152 ? 59.902 -3.759  20.156 1.00 30.85  ?  844  LEU   A O    1 
ATOM   2417 C  CB   . LEU   A 1 152 ? 57.035 -2.731  21.401 1.00 39.22  ?  844  LEU   A CB   1 
ATOM   2418 C  CG   . LEU   A 1 152 ? 55.789 -2.985  22.253 1.00 43.95  ?  844  LEU   A CG   1 
ATOM   2419 C  CD1  . LEU   A 1 152 ? 55.312 -1.695  22.893 1.00 34.52  ?  844  LEU   A CD1  1 
ATOM   2420 C  CD2  . LEU   A 1 152 ? 54.635 -3.620  21.504 1.00 32.96  ?  844  LEU   A CD2  1 
ATOM   2421 H  H    . LEU   A 1 152 ? 58.621 -4.889  22.157 1.00 31.70  ?  844  LEU   A H    1 
ATOM   2422 H  HA   . LEU   A 1 152 ? 56.795 -4.178  19.855 1.00 35.66  ?  844  LEU   A HA   1 
ATOM   2423 H  HB2  . LEU   A 1 152 ? 57.828 -2.376  22.059 1.00 41.22  ?  844  LEU   A HB2  1 
ATOM   2424 H  HB3  . LEU   A 1 152 ? 56.817 -1.906  20.720 1.00 41.22  ?  844  LEU   A HB3  1 
ATOM   2425 H  HG   . LEU   A 1 152 ? 56.075 -3.672  23.047 1.00 45.95  ?  844  LEU   A HG   1 
ATOM   2426 H  HD11 . LEU   A 1 152 ? 54.386 -1.836  23.450 1.00 36.52  ?  844  LEU   A HD11 1 
ATOM   2427 H  HD12 . LEU   A 1 152 ? 56.053 -1.298  23.587 1.00 36.52  ?  844  LEU   A HD12 1 
ATOM   2428 H  HD13 . LEU   A 1 152 ? 55.109 -0.928  22.144 1.00 36.52  ?  844  LEU   A HD13 1 
ATOM   2429 H  HD21 . LEU   A 1 152 ? 53.729 -3.646  22.111 1.00 34.96  ?  844  LEU   A HD21 1 
ATOM   2430 H  HD22 . LEU   A 1 152 ? 54.401 -3.076  20.588 1.00 34.96  ?  844  LEU   A HD22 1 
ATOM   2431 H  HD23 . LEU   A 1 152 ? 54.853 -4.656  21.253 1.00 34.96  ?  844  LEU   A HD23 1 
ATOM   2432 N  N    . VAL   A 1 153 ? 58.492 -2.767  18.683 1.00 33.92  ?  845  VAL   A N    1 
ATOM   2433 C  CA   . VAL   A 1 153 ? 59.491 -2.432  17.677 1.00 29.84  ?  845  VAL   A CA   1 
ATOM   2434 C  C    . VAL   A 1 153 ? 59.696 -0.915  17.650 1.00 35.93  ?  845  VAL   A C    1 
ATOM   2435 O  O    . VAL   A 1 153 ? 58.793 -0.156  17.278 1.00 35.09  ?  845  VAL   A O    1 
ATOM   2436 C  CB   . VAL   A 1 153 ? 59.004 -3.006  16.333 1.00 35.74  ?  845  VAL   A CB   1 
ATOM   2437 C  CG1  . VAL   A 1 153 ? 59.973 -2.782  15.183 1.00 32.32  ?  845  VAL   A CG1  1 
ATOM   2438 C  CG2  . VAL   A 1 153 ? 58.662 -4.494  16.424 1.00 33.38  ?  845  VAL   A CG2  1 
ATOM   2439 H  H    . VAL   A 1 153 ? 57.517 -2.617  18.427 1.00 35.92  ?  845  VAL   A H    1 
ATOM   2440 H  HA   . VAL   A 1 153 ? 60.451 -2.897  17.907 1.00 31.84  ?  845  VAL   A HA   1 
ATOM   2441 H  HB   . VAL   A 1 153 ? 58.070 -2.506  16.078 1.00 37.74  ?  845  VAL   A HB   1 
ATOM   2442 H  HG11 . VAL   A 1 153 ? 59.562 -3.146  14.240 1.00 34.32  ?  845  VAL   A HG11 1 
ATOM   2443 H  HG12 . VAL   A 1 153 ? 60.211 -1.729  15.041 1.00 34.32  ?  845  VAL   A HG12 1 
ATOM   2444 H  HG13 . VAL   A 1 153 ? 60.908 -3.317  15.356 1.00 34.32  ?  845  VAL   A HG13 1 
ATOM   2445 H  HG21 . VAL   A 1 153 ? 58.418 -4.904  15.444 1.00 35.38  ?  845  VAL   A HG21 1 
ATOM   2446 H  HG22 . VAL   A 1 153 ? 59.489 -5.077  16.827 1.00 35.38  ?  845  VAL   A HG22 1 
ATOM   2447 H  HG23 . VAL   A 1 153 ? 57.795 -4.672  17.058 1.00 35.38  ?  845  VAL   A HG23 1 
ATOM   2448 N  N    . LYS   A 1 154 ? 60.878 -0.461  18.068 1.00 35.50  ?  846  LYS   A N    1 
ATOM   2449 C  CA   . LYS   A 1 154 ? 61.198 0.970   18.024 1.00 35.09  ?  846  LYS   A CA   1 
ATOM   2450 C  C    . LYS   A 1 154 ? 61.648 1.342   16.615 1.00 39.20  ?  846  LYS   A C    1 
ATOM   2451 O  O    . LYS   A 1 154 ? 61.148 2.285   16.007 1.00 34.72  ?  846  LYS   A O    1 
ATOM   2452 C  CB   . LYS   A 1 154 ? 62.314 1.323   19.021 1.00 34.63  ?  846  LYS   A CB   1 
ATOM   2453 C  CG   . LYS   A 1 154 ? 62.814 2.771   18.968 1.00 30.81  ?  846  LYS   A CG   1 
ATOM   2454 C  CD   . LYS   A 1 154 ? 64.043 3.039   19.834 1.00 43.83  ?  846  LYS   A CD   1 
ATOM   2455 C  CE   . LYS   A 1 154 ? 64.643 4.406   19.518 1.00 36.23  ?  846  LYS   A CE   1 
ATOM   2456 N  NZ   . LYS   A 1 154 ? 65.774 4.757   20.391 1.00 44.30  1  846  LYS   A NZ   1 
ATOM   2457 H  H    . LYS   A 1 154 ? 61.630 -1.117  18.276 1.00 37.50  ?  846  LYS   A H    1 
ATOM   2458 H  HA   . LYS   A 1 154 ? 60.321 1.561   18.289 1.00 37.09  ?  846  LYS   A HA   1 
ATOM   2459 H  HB2  . LYS   A 1 154 ? 61.974 1.115   20.034 1.00 36.63  ?  846  LYS   A HB2  1 
ATOM   2460 H  HB3  . LYS   A 1 154 ? 63.166 0.662   18.859 1.00 36.63  ?  846  LYS   A HB3  1 
ATOM   2461 H  HG2  . LYS   A 1 154 ? 63.087 3.043   17.949 1.00 32.81  ?  846  LYS   A HG2  1 
ATOM   2462 H  HG3  . LYS   A 1 154 ? 62.005 3.448   19.250 1.00 32.81  ?  846  LYS   A HG3  1 
ATOM   2463 H  HD2  . LYS   A 1 154 ? 63.767 2.985   20.888 1.00 45.83  ?  846  LYS   A HD2  1 
ATOM   2464 H  HD3  . LYS   A 1 154 ? 64.798 2.270   19.666 1.00 45.83  ?  846  LYS   A HD3  1 
ATOM   2465 H  HE2  . LYS   A 1 154 ? 64.980 4.457   18.483 1.00 38.23  ?  846  LYS   A HE2  1 
ATOM   2466 H  HE3  . LYS   A 1 154 ? 63.871 5.163   19.630 1.00 38.23  ?  846  LYS   A HE3  1 
ATOM   2467 H  HZ1  . LYS   A 1 154 ? 65.863 5.764   20.422 1.00 46.30  ?  846  LYS   A HZ1  1 
ATOM   2468 H  HZ2  . LYS   A 1 154 ? 65.575 4.451   21.337 1.00 46.30  ?  846  LYS   A HZ2  1 
ATOM   2469 H  HZ3  . LYS   A 1 154 ? 66.630 4.332   20.068 1.00 46.30  ?  846  LYS   A HZ3  1 
ATOM   2470 N  N    . THR   A 1 155 ? 62.598 0.576   16.107 1.00 41.72  ?  847  THR   A N    1 
ATOM   2471 C  CA   . THR   A 1 155 ? 62.892 0.506   14.680 1.00 35.79  ?  847  THR   A CA   1 
ATOM   2472 C  C    . THR   A 1 155 ? 62.908 -0.977  14.346 1.00 38.14  ?  847  THR   A C    1 
ATOM   2473 O  O    . THR   A 1 155 ? 63.023 -1.789  15.271 1.00 38.66  ?  847  THR   A O    1 
ATOM   2474 C  CB   . THR   A 1 155 ? 64.208 1.206   14.312 1.00 30.74  ?  847  THR   A CB   1 
ATOM   2475 O  OG1  . THR   A 1 155 ? 65.348 0.494   14.749 1.00 39.37  ?  847  THR   A OG1  1 
ATOM   2476 C  CG2  . THR   A 1 155 ? 64.339 2.637   14.787 1.00 22.95  ?  847  THR   A CG2  1 
ATOM   2477 H  H    . THR   A 1 155 ? 62.937 -0.212  16.649 1.00 43.72  ?  847  THR   A H    1 
ATOM   2478 H  HA   . THR   A 1 155 ? 62.083 0.968   14.115 1.00 37.79  ?  847  THR   A HA   1 
ATOM   2479 H  HB   . THR   A 1 155 ? 64.278 1.237   13.225 1.00 32.74  ?  847  THR   A HB   1 
ATOM   2480 H  HG1  . THR   A 1 155 ? 66.076 0.745   14.189 1.00 41.37  ?  847  THR   A HG1  1 
ATOM   2481 H  HG21 . THR   A 1 155 ? 65.242 3.105   14.393 1.00 24.95  ?  847  THR   A HG21 1 
ATOM   2482 H  HG22 . THR   A 1 155 ? 63.491 3.235   14.451 1.00 24.95  ?  847  THR   A HG22 1 
ATOM   2483 H  HG23 . THR   A 1 155 ? 64.380 2.698   15.874 1.00 24.95  ?  847  THR   A HG23 1 
ATOM   2484 N  N    . PRO   A 1 156 ? 62.863 -1.398  13.073 1.00 44.30  ?  848  PRO   A N    1 
ATOM   2485 C  CA   . PRO   A 1 156 ? 63.102 -2.804  12.712 1.00 43.89  ?  848  PRO   A CA   1 
ATOM   2486 C  C    . PRO   A 1 156 ? 64.392 -3.416  13.263 1.00 32.48  ?  848  PRO   A C    1 
ATOM   2487 O  O    . PRO   A 1 156 ? 64.485 -4.623  13.465 1.00 39.16  ?  848  PRO   A O    1 
ATOM   2488 C  CB   . PRO   A 1 156 ? 63.096 -2.824  11.190 1.00 36.04  ?  848  PRO   A CB   1 
ATOM   2489 C  CG   . PRO   A 1 156 ? 62.262 -1.603  10.808 1.00 43.23  ?  848  PRO   A CG   1 
ATOM   2490 C  CD   . PRO   A 1 156 ? 62.485 -0.579  11.925 1.00 31.52  ?  848  PRO   A CD   1 
ATOM   2491 H  HA   . PRO   A 1 156 ? 62.258 -3.389  13.083 1.00 45.89  ?  848  PRO   A HA   1 
ATOM   2492 H  HB2  . PRO   A 1 156 ? 64.101 -2.710  10.783 1.00 38.04  ?  848  PRO   A HB2  1 
ATOM   2493 H  HB3  . PRO   A 1 156 ? 62.687 -3.753  10.792 1.00 38.04  ?  848  PRO   A HB3  1 
ATOM   2494 H  HG2  . PRO   A 1 156 ? 62.464 -1.229  9.807  1.00 45.23  ?  848  PRO   A HG2  1 
ATOM   2495 H  HG3  . PRO   A 1 156 ? 61.209 -1.878  10.832 1.00 45.23  ?  848  PRO   A HG3  1 
ATOM   2496 H  HD2  . PRO   A 1 156 ? 63.296 0.092   11.645 1.00 33.52  ?  848  PRO   A HD2  1 
ATOM   2497 H  HD3  . PRO   A 1 156 ? 61.582 0.005   12.101 1.00 33.52  ?  848  PRO   A HD3  1 
ATOM   2498 N  N    . GLN   A 1 157 ? 65.370 -2.565  13.546 1.00 24.44  ?  849  GLN   A N    1 
ATOM   2499 C  CA   . GLN   A 1 157 ? 66.644 -2.958  14.117 1.00 29.00  ?  849  GLN   A CA   1 
ATOM   2500 C  C    . GLN   A 1 157 ? 66.658 -2.960  15.654 1.00 33.06  ?  849  GLN   A C    1 
ATOM   2501 O  O    . GLN   A 1 157 ? 67.685 -3.300  16.245 1.00 36.67  ?  849  GLN   A O    1 
ATOM   2502 C  CB   . GLN   A 1 157 ? 67.714 -1.944  13.677 1.00 30.35  ?  849  GLN   A CB   1 
ATOM   2503 C  CG   . GLN   A 1 157 ? 67.933 -1.799  12.163 1.00 53.12  ?  849  GLN   A CG   1 
ATOM   2504 C  CD   . GLN   A 1 157 ? 66.951 -0.876  11.467 1.00 65.19  ?  849  GLN   A CD   1 
ATOM   2505 O  OE1  . GLN   A 1 157 ? 66.647 0.222   11.940 1.00 57.86  ?  849  GLN   A OE1  1 
ATOM   2506 N  NE2  . GLN   A 1 157 ? 66.439 -1.312  10.341 1.00 57.84  ?  849  GLN   A NE2  1 
ATOM   2507 H  H    . GLN   A 1 157 ? 65.218 -1.576  13.412 1.00 26.44  ?  849  GLN   A H    1 
ATOM   2508 H  HA   . GLN   A 1 157 ? 66.930 -3.955  13.772 1.00 31.00  ?  849  GLN   A HA   1 
ATOM   2509 H  HB2  . GLN   A 1 157 ? 67.525 -0.966  14.122 1.00 32.35  ?  849  GLN   A HB2  1 
ATOM   2510 H  HB3  . GLN   A 1 157 ? 68.673 -2.255  14.096 1.00 32.35  ?  849  GLN   A HB3  1 
ATOM   2511 H  HG2  . GLN   A 1 157 ? 68.923 -1.374  11.991 1.00 55.12  ?  849  GLN   A HG2  1 
ATOM   2512 H  HG3  . GLN   A 1 157 ? 67.947 -2.783  11.692 1.00 55.12  ?  849  GLN   A HG3  1 
ATOM   2513 H  HE21 . GLN   A 1 157 ? 66.711 -2.221  9.966  1.00 59.84  ?  849  GLN   A HE21 1 
ATOM   2514 H  HE22 . GLN   A 1 157 ? 65.754 -0.742  9.837  1.00 59.84  ?  849  GLN   A HE22 1 
ATOM   2515 N  N    . HIS   A 1 158 ? 65.575 -2.547  16.311 1.00 28.20  ?  850  HIS   A N    1 
ATOM   2516 C  CA   . HIS   A 1 158 ? 65.618 -2.300  17.750 1.00 32.82  ?  850  HIS   A CA   1 
ATOM   2517 C  C    . HIS   A 1 158 ? 64.284 -2.628  18.400 1.00 29.75  ?  850  HIS   A C    1 
ATOM   2518 O  O    . HIS   A 1 158 ? 63.315 -1.871  18.266 1.00 25.00  ?  850  HIS   A O    1 
ATOM   2519 C  CB   . HIS   A 1 158 ? 66.130 -0.898  18.066 1.00 28.45  ?  850  HIS   A CB   1 
ATOM   2520 C  CG   . HIS   A 1 158 ? 66.434 -0.598  19.518 1.00 29.08  ?  850  HIS   A CG   1 
ATOM   2521 N  ND1  . HIS   A 1 158 ? 66.996 0.620   19.944 1.00 38.43  ?  850  HIS   A ND1  1 
ATOM   2522 C  CD2  . HIS   A 1 158 ? 66.247 -1.403  20.651 1.00 33.10  ?  850  HIS   A CD2  1 
ATOM   2523 C  CE1  . HIS   A 1 158 ? 67.123 0.500   21.240 1.00 28.87  ?  850  HIS   A CE1  1 
ATOM   2524 N  NE2  . HIS   A 1 158 ? 66.700 -0.645  21.717 1.00 28.98  ?  850  HIS   A NE2  1 
ATOM   2525 H  H    . HIS   A 1 158 ? 64.722 -2.307  15.813 1.00 30.20  ?  850  HIS   A H    1 
ATOM   2526 H  HA   . HIS   A 1 158 ? 66.346 -2.972  18.202 1.00 34.82  ?  850  HIS   A HA   1 
ATOM   2527 H  HB2  . HIS   A 1 158 ? 67.057 -0.723  17.519 1.00 30.45  ?  850  HIS   A HB2  1 
ATOM   2528 H  HB3  . HIS   A 1 158 ? 65.422 -0.152  17.701 1.00 30.45  ?  850  HIS   A HB3  1 
ATOM   2529 H  HD2  . HIS   A 1 158 ? 65.853 -2.399  20.772 1.00 35.10  ?  850  HIS   A HD2  1 
ATOM   2530 H  HE1  . HIS   A 1 158 ? 67.533 1.282   21.865 1.00 30.87  ?  850  HIS   A HE1  1 
ATOM   2531 H  HE2  . HIS   A 1 158 ? 66.704 -0.931  22.703 1.00 30.98  ?  850  HIS   A HE2  1 
ATOM   2532 N  N    . VAL   A 1 159 ? 64.251 -3.737  19.131 1.00 21.72  ?  851  VAL   A N    1 
ATOM   2533 C  CA   . VAL   A 1 159 ? 63.048 -4.177  19.826 1.00 27.38  ?  851  VAL   A CA   1 
ATOM   2534 C  C    . VAL   A 1 159 ? 63.218 -4.088  21.341 1.00 22.91  ?  851  VAL   A C    1 
ATOM   2535 O  O    . VAL   A 1 159 ? 64.341 -4.080  21.865 1.00 25.98  ?  851  VAL   A O    1 
ATOM   2536 C  CB   . VAL   A 1 159 ? 62.619 -5.580  19.382 1.00 28.49  ?  851  VAL   A CB   1 
ATOM   2537 C  CG1  . VAL   A 1 159 ? 62.329 -5.645  17.888 1.00 27.55  ?  851  VAL   A CG1  1 
ATOM   2538 C  CG2  . VAL   A 1 159 ? 63.573 -6.695  19.793 1.00 22.84  ?  851  VAL   A CG2  1 
ATOM   2539 H  H    . VAL   A 1 159 ? 65.088 -4.315  19.212 1.00 23.72  ?  851  VAL   A H    1 
ATOM   2540 H  HA   . VAL   A 1 159 ? 62.227 -3.505  19.583 1.00 29.38  ?  851  VAL   A HA   1 
ATOM   2541 H  HB   . VAL   A 1 159 ? 61.673 -5.782  19.880 1.00 30.49  ?  851  VAL   A HB   1 
ATOM   2542 H  HG11 . VAL   A 1 159 ? 61.908 -6.608  17.600 1.00 29.55  ?  851  VAL   A HG11 1 
ATOM   2543 H  HG12 . VAL   A 1 159 ? 61.624 -4.873  17.588 1.00 29.55  ?  851  VAL   A HG12 1 
ATOM   2544 H  HG13 . VAL   A 1 159 ? 63.233 -5.500  17.297 1.00 29.55  ?  851  VAL   A HG13 1 
ATOM   2545 H  HG21 . VAL   A 1 159 ? 63.169 -7.669  19.515 1.00 24.84  ?  851  VAL   A HG21 1 
ATOM   2546 H  HG22 . VAL   A 1 159 ? 64.534 -6.601  19.293 1.00 24.84  ?  851  VAL   A HG22 1 
ATOM   2547 H  HG23 . VAL   A 1 159 ? 63.755 -6.728  20.867 1.00 24.84  ?  851  VAL   A HG23 1 
ATOM   2548 N  N    . LYS   A 1 160 ? 62.083 -4.016  22.033 1.00 22.75  ?  852  LYS   A N    1 
ATOM   2549 C  CA   . LYS   A 1 160 ? 62.051 -3.958  23.491 1.00 28.34  ?  852  LYS   A CA   1 
ATOM   2550 C  C    . LYS   A 1 160 ? 60.904 -4.781  24.043 1.00 24.22  ?  852  LYS   A C    1 
ATOM   2551 O  O    . LYS   A 1 160 ? 59.812 -4.778  23.477 1.00 31.40  ?  852  LYS   A O    1 
ATOM   2552 C  CB   . LYS   A 1 160 ? 61.953 -2.540  24.032 1.00 20.93  ?  852  LYS   A CB   1 
ATOM   2553 C  CG   . LYS   A 1 160 ? 62.968 -1.555  23.485 1.00 32.93  ?  852  LYS   A CG   1 
ATOM   2554 C  CD   . LYS   A 1 160 ? 62.917 -0.227  24.217 1.00 31.24  ?  852  LYS   A CD   1 
ATOM   2555 C  CE   . LYS   A 1 160 ? 63.787 0.823   23.552 1.00 36.50  ?  852  LYS   A CE   1 
ATOM   2556 N  NZ   . LYS   A 1 160 ? 63.954 1.968   24.439 1.00 27.05  1  852  LYS   A NZ   1 
ATOM   2557 H  H    . LYS   A 1 160 ? 61.196 -4.043  21.534 1.00 24.75  ?  852  LYS   A H    1 
ATOM   2558 H  HA   . LYS   A 1 160 ? 62.968 -4.409  23.869 1.00 30.34  ?  852  LYS   A HA   1 
ATOM   2559 H  HB2  . LYS   A 1 160 ? 60.952 -2.150  23.853 1.00 22.93  ?  852  LYS   A HB2  1 
ATOM   2560 H  HB3  . LYS   A 1 160 ? 62.053 -2.581  25.117 1.00 22.93  ?  852  LYS   A HB3  1 
ATOM   2561 H  HG2  . LYS   A 1 160 ? 63.969 -1.968  23.562 1.00 34.93  ?  852  LYS   A HG2  1 
ATOM   2562 H  HG3  . LYS   A 1 160 ? 62.805 -1.398  22.420 1.00 34.93  ?  852  LYS   A HG3  1 
ATOM   2563 H  HD2  . LYS   A 1 160 ? 61.890 0.142   24.266 1.00 33.24  ?  852  LYS   A HD2  1 
ATOM   2564 H  HD3  . LYS   A 1 160 ? 63.242 -0.380  25.248 1.00 33.24  ?  852  LYS   A HD3  1 
ATOM   2565 H  HE2  . LYS   A 1 160 ? 64.774 0.432   23.320 1.00 38.50  ?  852  LYS   A HE2  1 
ATOM   2566 H  HE3  . LYS   A 1 160 ? 63.343 1.156   22.613 1.00 38.50  ?  852  LYS   A HE3  1 
ATOM   2567 H  HZ1  . LYS   A 1 160 ? 64.546 2.681   24.028 1.00 29.05  ?  852  LYS   A HZ1  1 
ATOM   2568 H  HZ2  . LYS   A 1 160 ? 63.054 2.393   24.622 1.00 29.05  ?  852  LYS   A HZ2  1 
ATOM   2569 H  HZ3  . LYS   A 1 160 ? 64.365 1.673   25.312 1.00 29.05  ?  852  LYS   A HZ3  1 
ATOM   2570 N  N    . ILE   A 1 161 ? 61.132 -5.419  25.184 1.00 32.67  ?  853  ILE   A N    1 
ATOM   2571 C  CA   . ILE   A 1 161 ? 60.075 -6.151  25.882 1.00 34.08  ?  853  ILE   A CA   1 
ATOM   2572 C  C    . ILE   A 1 161 ? 59.182 -5.178  26.652 1.00 29.58  ?  853  ILE   A C    1 
ATOM   2573 O  O    . ILE   A 1 161 ? 59.660 -4.204  27.250 1.00 30.23  ?  853  ILE   A O    1 
ATOM   2574 C  CB   . ILE   A 1 161 ? 60.718 -7.163  26.850 1.00 37.21  ?  853  ILE   A CB   1 
ATOM   2575 C  CG1  . ILE   A 1 161 ? 61.567 -8.196  26.105 1.00 27.73  ?  853  ILE   A CG1  1 
ATOM   2576 C  CG2  . ILE   A 1 161 ? 59.730 -7.902  27.760 1.00 29.28  ?  853  ILE   A CG2  1 
ATOM   2577 C  CD1  . ILE   A 1 161 ? 62.799 -8.562  26.892 1.00 35.24  ?  853  ILE   A CD1  1 
ATOM   2578 H  H    . ILE   A 1 161 ? 62.048 -5.363  25.621 1.00 34.67  ?  853  ILE   A H    1 
ATOM   2579 H  HA   . ILE   A 1 161 ? 59.472 -6.705  25.159 1.00 36.08  ?  853  ILE   A HA   1 
ATOM   2580 H  HB   . ILE   A 1 161 ? 61.373 -6.586  27.508 1.00 39.21  ?  853  ILE   A HB   1 
ATOM   2581 H  HG12 . ILE   A 1 161 ? 60.981 -9.091  25.887 1.00 29.73  ?  853  ILE   A HG12 1 
ATOM   2582 H  HG13 . ILE   A 1 161 ? 61.896 -7.831  25.132 1.00 29.73  ?  853  ILE   A HG13 1 
ATOM   2583 H  HG21 . ILE   A 1 161 ? 60.229 -8.668  28.353 1.00 31.28  ?  853  ILE   A HG21 1 
ATOM   2584 H  HG22 . ILE   A 1 161 ? 59.243 -7.235  28.472 1.00 31.28  ?  853  ILE   A HG22 1 
ATOM   2585 H  HG23 . ILE   A 1 161 ? 58.948 -8.398  27.183 1.00 31.28  ?  853  ILE   A HG23 1 
ATOM   2586 H  HD11 . ILE   A 1 161 ? 63.412 -9.282  26.354 1.00 37.24  ?  853  ILE   A HD11 1 
ATOM   2587 H  HD12 . ILE   A 1 161 ? 63.393 -7.670  27.064 1.00 37.24  ?  853  ILE   A HD12 1 
ATOM   2588 H  HD13 . ILE   A 1 161 ? 62.554 -8.979  27.866 1.00 37.24  ?  853  ILE   A HD13 1 
ATOM   2589 N  N    . THR   A 1 162 ? 57.892 -5.479  26.649 1.00 34.60  ?  854  THR   A N    1 
ATOM   2590 C  CA   . THR   A 1 162 ? 56.920 -4.740  27.416 1.00 40.48  ?  854  THR   A CA   1 
ATOM   2591 C  C    . THR   A 1 162 ? 55.978 -5.690  28.148 1.00 44.99  ?  854  THR   A C    1 
ATOM   2592 O  O    . THR   A 1 162 ? 56.205 -6.906  28.221 1.00 28.57  ?  854  THR   A O    1 
ATOM   2593 C  CB   . THR   A 1 162 ? 56.269 -3.642  26.562 1.00 49.90  ?  854  THR   A CB   1 
ATOM   2594 O  OG1  . THR   A 1 162 ? 55.693 -2.695  27.444 1.00 63.64  ?  854  THR   A OG1  1 
ATOM   2595 C  CG2  . THR   A 1 162 ? 55.201 -4.160  25.607 1.00 40.58  ?  854  THR   A CG2  1 
ATOM   2596 H  H    . THR   A 1 162 ? 57.558 -6.312  26.165 1.00 36.60  ?  854  THR   A H    1 
ATOM   2597 H  HA   . THR   A 1 162 ? 57.441 -4.240  28.236 1.00 42.48  ?  854  THR   A HA   1 
ATOM   2598 H  HB   . THR   A 1 162 ? 57.035 -3.125  25.985 1.00 51.90  ?  854  THR   A HB   1 
ATOM   2599 H  HG1  . THR   A 1 162 ? 55.271 -1.977  26.967 1.00 65.64  ?  854  THR   A HG1  1 
ATOM   2600 H  HG21 . THR   A 1 162 ? 54.771 -3.352  25.023 1.00 42.58  ?  854  THR   A HG21 1 
ATOM   2601 H  HG22 . THR   A 1 162 ? 55.616 -4.896  24.918 1.00 42.58  ?  854  THR   A HG22 1 
ATOM   2602 H  HG23 . THR   A 1 162 ? 54.367 -4.638  26.120 1.00 42.58  ?  854  THR   A HG23 1 
ATOM   2603 N  N    . ASP   A 1 163 ? 54.942 -5.074  28.712 1.00 43.37  ?  855  ASP   A N    1 
ATOM   2604 C  CA   . ASP   A 1 163 ? 53.835 -5.722  29.399 1.00 41.09  ?  855  ASP   A CA   1 
ATOM   2605 C  C    . ASP   A 1 163 ? 54.257 -6.289  30.737 1.00 48.24  ?  855  ASP   A C    1 
ATOM   2606 O  O    . ASP   A 1 163 ? 54.550 -7.477  30.869 1.00 48.43  ?  855  ASP   A O    1 
ATOM   2607 C  CB   . ASP   A 1 163 ? 53.023 -6.685  28.537 1.00 53.38  ?  855  ASP   A CB   1 
ATOM   2608 C  CG   . ASP   A 1 163 ? 51.586 -6.764  29.010 1.00 66.78  ?  855  ASP   A CG   1 
ATOM   2609 O  OD1  . ASP   A 1 163 ? 51.355 -7.129  30.184 1.00 71.80  ?  855  ASP   A OD1  1 
ATOM   2610 O  OD2  . ASP   A 1 163 ? 50.673 -6.456  28.216 1.00 75.33  -1 855  ASP   A OD2  1 
ATOM   2611 H  H    . ASP   A 1 163 ? 54.908 -4.069  28.562 1.00 45.37  ?  855  ASP   A H    1 
ATOM   2612 H  HA   . ASP   A 1 163 ? 53.175 -4.877  29.614 1.00 43.09  ?  855  ASP   A HA   1 
ATOM   2613 H  HB2  . ASP   A 1 163 ? 53.018 -6.349  27.500 1.00 55.38  ?  855  ASP   A HB2  1 
ATOM   2614 H  HB3  . ASP   A 1 163 ? 53.461 -7.683  28.536 1.00 55.38  ?  855  ASP   A HB3  1 
ATOM   2615 N  N    . PHE   A 1 164 ? 54.285 -5.415  31.734 1.00 59.30  ?  856  PHE   A N    1 
ATOM   2616 C  CA   . PHE   A 1 164 ? 54.762 -5.803  33.060 1.00 52.86  ?  856  PHE   A CA   1 
ATOM   2617 C  C    . PHE   A 1 164 ? 53.622 -6.086  34.028 1.00 49.09  ?  856  PHE   A C    1 
ATOM   2618 O  O    . PHE   A 1 164 ? 53.810 -6.113  35.244 1.00 53.69  ?  856  PHE   A O    1 
ATOM   2619 C  CB   . PHE   A 1 164 ? 55.743 -4.755  33.583 1.00 52.62  ?  856  PHE   A CB   1 
ATOM   2620 C  CG   . PHE   A 1 164 ? 57.084 -4.903  32.886 1.00 55.24  ?  856  PHE   A CG   1 
ATOM   2621 C  CD1  . PHE   A 1 164 ? 57.983 -5.903  33.306 1.00 48.93  ?  856  PHE   A CD1  1 
ATOM   2622 C  CD2  . PHE   A 1 164 ? 57.422 -4.062  31.803 1.00 51.42  ?  856  PHE   A CD2  1 
ATOM   2623 C  CE1  . PHE   A 1 164 ? 59.206 -6.074  32.643 1.00 48.63  ?  856  PHE   A CE1  1 
ATOM   2624 C  CE2  . PHE   A 1 164 ? 58.652 -4.237  31.138 1.00 36.33  ?  856  PHE   A CE2  1 
ATOM   2625 C  CZ   . PHE   A 1 164 ? 59.540 -5.248  31.558 1.00 58.70  ?  856  PHE   A CZ   1 
ATOM   2626 H  H    . PHE   A 1 164 ? 54.004 -4.460  31.572 1.00 61.30  ?  856  PHE   A H    1 
ATOM   2627 H  HA   . PHE   A 1 164 ? 55.312 -6.746  33.028 1.00 54.86  ?  856  PHE   A HA   1 
ATOM   2628 H  HB2  . PHE   A 1 164 ? 55.349 -3.744  33.466 1.00 54.62  ?  856  PHE   A HB2  1 
ATOM   2629 H  HB3  . PHE   A 1 164 ? 55.921 -4.887  34.651 1.00 54.62  ?  856  PHE   A HB3  1 
ATOM   2630 H  HD1  . PHE   A 1 164 ? 57.727 -6.546  34.131 1.00 50.93  ?  856  PHE   A HD1  1 
ATOM   2631 H  HD2  . PHE   A 1 164 ? 56.734 -3.297  31.475 1.00 53.42  ?  856  PHE   A HD2  1 
ATOM   2632 H  HE1  . PHE   A 1 164 ? 59.889 -6.847  32.963 1.00 50.63  ?  856  PHE   A HE1  1 
ATOM   2633 H  HE2  . PHE   A 1 164 ? 58.911 -3.601  30.303 1.00 38.33  ?  856  PHE   A HE2  1 
ATOM   2634 H  HZ   . PHE   A 1 164 ? 60.474 -5.395  31.047 1.00 60.70  ?  856  PHE   A HZ   1 
ATOM   2635 N  N    . GLY   A 1 165 ? 52.445 -6.400  33.495 1.00 49.59  ?  857  GLY   A N    1 
ATOM   2636 C  CA   . GLY   A 1 165 ? 51.278 -6.551  34.352 1.00 53.01  ?  857  GLY   A CA   1 
ATOM   2637 C  C    . GLY   A 1 165 ? 51.088 -7.936  34.941 1.00 56.02  ?  857  GLY   A C    1 
ATOM   2638 O  O    . GLY   A 1 165 ? 50.120 -8.174  35.664 1.00 56.86  ?  857  GLY   A O    1 
ATOM   2639 H  H    . GLY   A 1 165 ? 52.349 -6.490  32.490 1.00 51.59  ?  857  GLY   A H    1 
ATOM   2640 H  HA2  . GLY   A 1 165 ? 51.279 -5.819  35.162 1.00 55.01  ?  857  GLY   A HA2  1 
ATOM   2641 H  HA3  . GLY   A 1 165 ? 50.397 -6.324  33.752 1.00 55.01  ?  857  GLY   A HA3  1 
ATOM   2642 N  N    . ARG   A 1 166 ? 52.023 -8.838  34.664 1.00 52.30  ?  858  ARG   A N    1 
ATOM   2643 C  CA   . ARG   A 1 166 ? 52.124 -10.097 35.385 1.00 43.00  ?  858  ARG   A CA   1 
ATOM   2644 C  C    . ARG   A 1 166 ? 53.466 -10.231 36.079 1.00 41.58  ?  858  ARG   A C    1 
ATOM   2645 O  O    . ARG   A 1 166 ? 53.724 -11.249 36.725 1.00 43.12  ?  858  ARG   A O    1 
ATOM   2646 C  CB   . ARG   A 1 166 ? 51.829 -11.282 34.465 1.00 49.99  ?  858  ARG   A CB   1 
ATOM   2647 C  CG   . ARG   A 1 166 ? 50.348 -11.424 34.113 1.00 57.50  ?  858  ARG   A CG   1 
ATOM   2648 C  CD   . ARG   A 1 166 ? 50.021 -12.476 33.054 1.00 63.21  ?  858  ARG   A CD   1 
ATOM   2649 N  NE   . ARG   A 1 166 ? 50.826 -13.704 33.198 1.00 74.49  ?  858  ARG   A NE   1 
ATOM   2650 C  CZ   . ARG   A 1 166 ? 50.530 -14.702 34.044 1.00 70.84  ?  858  ARG   A CZ   1 
ATOM   2651 N  NH1  . ARG   A 1 166 ? 49.442 -14.631 34.823 1.00 83.38  ?  858  ARG   A NH1  1 
ATOM   2652 N  NH2  . ARG   A 1 166 ? 51.328 -15.771 34.108 1.00 60.78  1  858  ARG   A NH2  1 
ATOM   2653 H  H    . ARG   A 1 166 ? 52.770 -8.631  34.002 1.00 54.30  ?  858  ARG   A H    1 
ATOM   2654 H  HA   . ARG   A 1 166 ? 51.410 -10.143 36.211 1.00 45.00  ?  858  ARG   A HA   1 
ATOM   2655 H  HB2  . ARG   A 1 166 ? 52.424 -11.192 33.554 1.00 51.99  ?  858  ARG   A HB2  1 
ATOM   2656 H  HB3  . ARG   A 1 166 ? 52.153 -12.209 34.937 1.00 51.99  ?  858  ARG   A HB3  1 
ATOM   2657 H  HG2  . ARG   A 1 166 ? 49.783 -11.641 35.020 1.00 59.50  ?  858  ARG   A HG2  1 
ATOM   2658 H  HG3  . ARG   A 1 166 ? 49.969 -10.466 33.756 1.00 59.50  ?  858  ARG   A HG3  1 
ATOM   2659 H  HD2  . ARG   A 1 166 ? 48.955 -12.706 33.046 1.00 65.21  ?  858  ARG   A HD2  1 
ATOM   2660 H  HD3  . ARG   A 1 166 ? 50.240 -12.062 32.069 1.00 65.21  ?  858  ARG   A HD3  1 
ATOM   2661 H  HE   . ARG   A 1 166 ? 51.659 -13.780 32.619 1.00 76.49  ?  858  ARG   A HE   1 
ATOM   2662 H  HH11 . ARG   A 1 166 ? 48.837 -13.821 34.776 1.00 85.38  ?  858  ARG   A HH11 1 
ATOM   2663 H  HH12 . ARG   A 1 166 ? 49.220 -15.382 35.466 1.00 85.38  ?  858  ARG   A HH12 1 
ATOM   2664 H  HH21 . ARG   A 1 166 ? 52.152 -15.818 33.517 1.00 62.78  ?  858  ARG   A HH21 1 
ATOM   2665 H  HH22 . ARG   A 1 166 ? 51.123 -16.526 34.748 1.00 62.78  ?  858  ARG   A HH22 1 
ATOM   2666 N  N    . ALA   A 1 167 ? 54.330 -9.224  35.970 1.00 40.56  ?  859  ALA   A N    1 
ATOM   2667 C  CA   . ALA   A 1 167 ? 55.700 -9.403  36.426 1.00 43.32  ?  859  ALA   A CA   1 
ATOM   2668 C  C    . ALA   A 1 167 ? 55.792 -9.408  37.941 1.00 57.47  ?  859  ALA   A C    1 
ATOM   2669 O  O    . ALA   A 1 167 ? 55.107 -8.647  38.629 1.00 64.75  ?  859  ALA   A O    1 
ATOM   2670 C  CB   . ALA   A 1 167 ? 56.587 -8.311  35.874 1.00 35.90  ?  859  ALA   A CB   1 
ATOM   2671 H  H    . ALA   A 1 167 ? 54.061 -8.365  35.513 1.00 42.56  ?  859  ALA   A H    1 
ATOM   2672 H  HA   . ALA   A 1 167 ? 56.062 -10.357 36.044 1.00 45.32  ?  859  ALA   A HA   1 
ATOM   2673 H  HB1  . ALA   A 1 167 ? 57.626 -8.449  36.178 1.00 37.90  ?  859  ALA   A HB1  1 
ATOM   2674 H  HB2  . ALA   A 1 167 ? 56.559 -8.330  34.784 1.00 37.90  ?  859  ALA   A HB2  1 
ATOM   2675 H  HB3  . ALA   A 1 167 ? 56.265 -7.322  36.205 1.00 37.90  ?  859  ALA   A HB3  1 
ATOM   2676 N  N    . LYS   A 1 168 ? 56.652 -10.281 38.445 1.00 59.70  ?  860  LYS   A N    1 
ATOM   2677 C  CA   . LYS   A 1 168 ? 56.826 -10.452 39.873 1.00 56.73  ?  860  LYS   A CA   1 
ATOM   2678 C  C    . LYS   A 1 168 ? 58.307 -10.489 40.186 1.00 59.15  ?  860  LYS   A C    1 
ATOM   2679 O  O    . LYS   A 1 168 ? 59.111 -11.032 39.426 1.00 66.43  ?  860  LYS   A O    1 
ATOM   2680 C  CB   . LYS   A 1 168 ? 56.009 -11.635 40.399 1.00 65.50  ?  860  LYS   A CB   1 
ATOM   2681 C  CG   . LYS   A 1 168 ? 56.097 -11.837 41.911 1.00 92.70  ?  860  LYS   A CG   1 
ATOM   2682 C  CD   . LYS   A 1 168 ? 55.067 -12.804 42.482 1.00 108.67 ?  860  LYS   A CD   1 
ATOM   2683 C  CE   . LYS   A 1 168 ? 55.245 -12.999 43.984 1.00 114.92 ?  860  LYS   A CE   1 
ATOM   2684 N  NZ   . LYS   A 1 168 ? 54.188 -13.848 44.554 1.00 121.87 1  860  LYS   A NZ   1 
ATOM   2685 H  H    . LYS   A 1 168 ? 57.249 -10.816 37.817 1.00 61.70  ?  860  LYS   A H    1 
ATOM   2686 H  HA   . LYS   A 1 168 ? 56.446 -9.566  40.389 1.00 58.73  ?  860  LYS   A HA   1 
ATOM   2687 H  HB2  . LYS   A 1 168 ? 54.964 -11.481 40.123 1.00 67.50  ?  860  LYS   A HB2  1 
ATOM   2688 H  HB3  . LYS   A 1 168 ? 56.321 -12.552 39.896 1.00 67.50  ?  860  LYS   A HB3  1 
ATOM   2689 H  HG2  . LYS   A 1 168 ? 57.092 -12.204 42.163 1.00 94.70  ?  860  LYS   A HG2  1 
ATOM   2690 H  HG3  . LYS   A 1 168 ? 55.986 -10.875 42.413 1.00 94.70  ?  860  LYS   A HG3  1 
ATOM   2691 H  HD2  . LYS   A 1 168 ? 54.064 -12.427 42.277 1.00 110.67 ?  860  LYS   A HD2  1 
ATOM   2692 H  HD3  . LYS   A 1 168 ? 55.146 -13.768 41.978 1.00 110.67 ?  860  LYS   A HD3  1 
ATOM   2693 H  HE2  . LYS   A 1 168 ? 56.214 -13.450 44.202 1.00 116.92 ?  860  LYS   A HE2  1 
ATOM   2694 H  HE3  . LYS   A 1 168 ? 55.216 -12.038 44.499 1.00 116.92 ?  860  LYS   A HE3  1 
ATOM   2695 H  HZ1  . LYS   A 1 168 ? 54.216 -14.771 44.143 1.00 123.87 ?  860  LYS   A HZ1  1 
ATOM   2696 H  HZ2  . LYS   A 1 168 ? 54.321 -13.913 45.552 1.00 123.87 ?  860  LYS   A HZ2  1 
ATOM   2697 H  HZ3  . LYS   A 1 168 ? 53.283 -13.426 44.369 1.00 123.87 ?  860  LYS   A HZ3  1 
ATOM   2698 N  N    . LEU   A 1 169 ? 58.660 -9.900  41.321 1.00 72.75  ?  861  LEU   A N    1 
ATOM   2699 C  CA   . LEU   A 1 169 ? 60.012 -9.988  41.847 1.00 86.71  ?  861  LEU   A CA   1 
ATOM   2700 C  C    . LEU   A 1 169 ? 60.209 -11.365 42.469 1.00 94.89  ?  861  LEU   A C    1 
ATOM   2701 O  O    . LEU   A 1 169 ? 59.400 -11.827 43.278 1.00 105.08 ?  861  LEU   A O    1 
ATOM   2702 C  CB   . LEU   A 1 169 ? 60.182 -8.879  42.894 1.00 84.30  ?  861  LEU   A CB   1 
ATOM   2703 C  CG   . LEU   A 1 169 ? 61.517 -8.780  43.638 1.00 91.11  ?  861  LEU   A CG   1 
ATOM   2704 C  CD1  . LEU   A 1 169 ? 62.633 -8.257  42.751 1.00 92.07  ?  861  LEU   A CD1  1 
ATOM   2705 C  CD2  . LEU   A 1 169 ? 61.383 -7.894  44.867 1.00 94.39  ?  861  LEU   A CD2  1 
ATOM   2706 H  H    . LEU   A 1 169 ? 57.946 -9.519  41.919 1.00 74.75  ?  861  LEU   A H    1 
ATOM   2707 H  HA   . LEU   A 1 169 ? 60.733 -9.829  41.045 1.00 88.71  ?  861  LEU   A HA   1 
ATOM   2708 H  HB2  . LEU   A 1 169 ? 59.987 -7.917  42.416 1.00 86.30  ?  861  LEU   A HB2  1 
ATOM   2709 H  HB3  . LEU   A 1 169 ? 59.387 -8.989  43.630 1.00 86.30  ?  861  LEU   A HB3  1 
ATOM   2710 H  HG   . LEU   A 1 169 ? 61.805 -9.766  44.005 1.00 93.11  ?  861  LEU   A HG   1 
ATOM   2711 H  HD11 . LEU   A 1 169 ? 63.578 -8.227  43.296 1.00 94.07  ?  861  LEU   A HD11 1 
ATOM   2712 H  HD12 . LEU   A 1 169 ? 62.780 -8.888  41.880 1.00 94.07  ?  861  LEU   A HD12 1 
ATOM   2713 H  HD13 . LEU   A 1 169 ? 62.428 -7.248  42.393 1.00 94.07  ?  861  LEU   A HD13 1 
ATOM   2714 H  HD21 . LEU   A 1 169 ? 62.316 -7.856  45.429 1.00 96.39  ?  861  LEU   A HD21 1 
ATOM   2715 H  HD22 . LEU   A 1 169 ? 61.117 -6.871  44.597 1.00 96.39  ?  861  LEU   A HD22 1 
ATOM   2716 H  HD23 . LEU   A 1 169 ? 60.617 -8.267  45.548 1.00 96.39  ?  861  LEU   A HD23 1 
ATOM   2717 N  N    . LEU   A 1 170 ? 61.292 -12.019 42.082 1.00 110.65 ?  862  LEU   A N    1 
ATOM   2718 C  CA   . LEU   A 1 170 ? 61.686 -13.278 42.684 1.00 124.91 ?  862  LEU   A CA   1 
ATOM   2719 C  C    . LEU   A 1 170 ? 62.349 -12.949 44.017 1.00 136.99 ?  862  LEU   A C    1 
ATOM   2720 O  O    . LEU   A 1 170 ? 63.478 -12.454 44.082 1.00 137.32 ?  862  LEU   A O    1 
ATOM   2721 C  CB   . LEU   A 1 170 ? 62.657 -14.029 41.761 1.00 127.42 ?  862  LEU   A CB   1 
ATOM   2722 C  CG   . LEU   A 1 170 ? 62.423 -15.537 41.696 1.00 131.33 ?  862  LEU   A CG   1 
ATOM   2723 C  CD1  . LEU   A 1 170 ? 63.283 -16.175 40.619 1.00 133.16 ?  862  LEU   A CD1  1 
ATOM   2724 C  CD2  . LEU   A 1 170 ? 62.658 -16.227 43.029 1.00 139.82 ?  862  LEU   A CD2  1 
ATOM   2725 H  H    . LEU   A 1 170 ? 61.944 -11.569 41.435 1.00 112.65 ?  862  LEU   A H    1 
ATOM   2726 H  HA   . LEU   A 1 170 ? 60.795 -13.893 42.833 1.00 126.91 ?  862  LEU   A HA   1 
ATOM   2727 H  HB2  . LEU   A 1 170 ? 62.557 -13.635 40.751 1.00 129.42 ?  862  LEU   A HB2  1 
ATOM   2728 H  HB3  . LEU   A 1 170 ? 63.701 -13.828 42.013 1.00 129.42 ?  862  LEU   A HB3  1 
ATOM   2729 H  HG   . LEU   A 1 170 ? 61.382 -15.703 41.412 1.00 133.33 ?  862  LEU   A HG   1 
ATOM   2730 H  HD11 . LEU   A 1 170 ? 63.076 -17.242 40.523 1.00 135.16 ?  862  LEU   A HD11 1 
ATOM   2731 H  HD12 . LEU   A 1 170 ? 63.103 -15.720 39.646 1.00 135.16 ?  862  LEU   A HD12 1 
ATOM   2732 H  HD13 . LEU   A 1 170 ? 64.345 -16.059 40.838 1.00 135.16 ?  862  LEU   A HD13 1 
ATOM   2733 H  HD21 . LEU   A 1 170 ? 62.513 -17.305 42.945 1.00 141.82 ?  862  LEU   A HD21 1 
ATOM   2734 H  HD22 . LEU   A 1 170 ? 63.673 -16.058 43.391 1.00 141.82 ?  862  LEU   A HD22 1 
ATOM   2735 H  HD23 . LEU   A 1 170 ? 61.970 -15.876 43.798 1.00 141.82 ?  862  LEU   A HD23 1 
ATOM   2736 N  N    . GLY   A 1 171 ? 61.577 -13.169 45.069 1.00 148.17 ?  863  GLY   A N    1 
ATOM   2737 C  CA   . GLY   A 1 171 ? 61.912 -12.614 46.372 1.00 160.58 ?  863  GLY   A CA   1 
ATOM   2738 C  C    . GLY   A 1 171 ? 60.826 -11.671 46.832 1.00 167.89 ?  863  GLY   A C    1 
ATOM   2739 O  O    . GLY   A 1 171 ? 61.086 -10.517 47.164 1.00 168.34 ?  863  GLY   A O    1 
ATOM   2740 H  H    . GLY   A 1 171 ? 60.620 -13.425 44.883 1.00 150.17 ?  863  GLY   A H    1 
ATOM   2741 H  HA2  . GLY   A 1 171 ? 62.003 -13.429 47.088 1.00 162.58 ?  863  GLY   A HA2  1 
ATOM   2742 H  HA3  . GLY   A 1 171 ? 62.867 -12.085 46.399 1.00 162.58 ?  863  GLY   A HA3  1 
ATOM   2743 N  N    . ALA   A 1 172 ? 59.593 -12.166 46.796 1.00 173.56 ?  864  ALA   A N    1 
ATOM   2744 C  CA   . ALA   A 1 172 ? 58.425 -11.357 47.109 1.00 177.19 ?  864  ALA   A CA   1 
ATOM   2745 C  C    . ALA   A 1 172 ? 57.402 -12.183 47.860 1.00 179.98 ?  864  ALA   A C    1 
ATOM   2746 O  O    . ALA   A 1 172 ? 56.274 -12.396 47.408 1.00 180.62 ?  864  ALA   A O    1 
ATOM   2747 C  CB   . ALA   A 1 172 ? 57.888 -10.620 45.897 1.00 177.67 ?  864  ALA   A CB   1 
ATOM   2748 H  H    . ALA   A 1 172 ? 59.452 -13.135 46.558 1.00 175.56 ?  864  ALA   A H    1 
ATOM   2749 H  HA   . ALA   A 1 172 ? 58.709 -10.580 47.823 1.00 179.19 ?  864  ALA   A HA   1 
ATOM   2750 H  HB1  . ALA   A 1 172 ? 57.034 -9.995  46.158 1.00 179.67 ?  864  ALA   A HB1  1 
ATOM   2751 H  HB2  . ALA   A 1 172 ? 58.654 -9.969  45.479 1.00 179.67 ?  864  ALA   A HB2  1 
ATOM   2752 H  HB3  . ALA   A 1 172 ? 57.572 -11.311 45.116 1.00 179.67 ?  864  ALA   A HB3  1 
ATOM   2753 N  N    . ALA   A 1 173 ? 57.854 -12.712 48.991 1.00 182.53 ?  865  ALA   A N    1 
ATOM   2754 C  CA   . ALA   A 1 173 ? 57.000 -13.347 49.991 1.00 184.94 ?  865  ALA   A CA   1 
ATOM   2755 C  C    . ALA   A 1 173 ? 56.703 -14.816 49.767 1.00 186.38 ?  865  ALA   A C    1 
ATOM   2756 O  O    . ALA   A 1 173 ? 55.730 -15.344 50.300 1.00 187.19 ?  865  ALA   A O    1 
ATOM   2757 C  CB   . ALA   A 1 173 ? 55.786 -12.542 50.415 1.00 183.21 ?  865  ALA   A CB   1 
ATOM   2758 H  H    . ALA   A 1 173 ? 58.835 -12.579 49.214 1.00 184.53 ?  865  ALA   A H    1 
ATOM   2759 H  HA   . ALA   A 1 173 ? 57.643 -13.363 50.871 1.00 186.94 ?  865  ALA   A HA   1 
ATOM   2760 H  HB1  . ALA   A 1 173 ? 55.389 -12.894 51.367 1.00 185.21 ?  865  ALA   A HB1  1 
ATOM   2761 H  HB2  . ALA   A 1 173 ? 56.025 -11.487 50.519 1.00 185.21 ?  865  ALA   A HB2  1 
ATOM   2762 H  HB3  . ALA   A 1 173 ? 54.982 -12.624 49.683 1.00 185.21 ?  865  ALA   A HB3  1 
ATOM   2763 N  N    . ALA   A 1 174 ? 57.504 -15.473 48.938 1.00 186.56 ?  866  ALA   A N    1 
ATOM   2764 C  CA   . ALA   A 1 174 ? 57.466 -16.926 48.756 1.00 184.72 ?  866  ALA   A CA   1 
ATOM   2765 C  C    . ALA   A 1 174 ? 56.313 -17.464 47.919 1.00 184.21 ?  866  ALA   A C    1 
ATOM   2766 O  O    . ALA   A 1 174 ? 56.277 -18.652 47.595 1.00 183.80 ?  866  ALA   A O    1 
ATOM   2767 C  CB   . ALA   A 1 174 ? 57.638 -17.728 50.041 1.00 182.71 ?  866  ALA   A CB   1 
ATOM   2768 H  H    . ALA   A 1 174 ? 58.290 -14.964 48.551 1.00 188.56 ?  866  ALA   A H    1 
ATOM   2769 H  HA   . ALA   A 1 174 ? 58.357 -17.124 48.158 1.00 186.72 ?  866  ALA   A HA   1 
ATOM   2770 H  HB1  . ALA   A 1 174 ? 58.299 -17.240 50.753 1.00 184.71 ?  866  ALA   A HB1  1 
ATOM   2771 H  HB2  . ALA   A 1 174 ? 56.684 -17.884 50.542 1.00 184.71 ?  866  ALA   A HB2  1 
ATOM   2772 H  HB3  . ALA   A 1 174 ? 58.052 -18.714 49.827 1.00 184.71 ?  866  ALA   A HB3  1 
ATOM   2773 N  N    . ALA   A 1 175 ? 55.361 -16.602 47.577 1.00 183.93 ?  867  ALA   A N    1 
ATOM   2774 C  CA   . ALA   A 1 175 ? 54.065 -17.026 47.055 1.00 183.68 ?  867  ALA   A CA   1 
ATOM   2775 C  C    . ALA   A 1 175 ? 54.080 -17.308 45.554 1.00 183.61 ?  867  ALA   A C    1 
ATOM   2776 O  O    . ALA   A 1 175 ? 53.209 -16.884 44.791 1.00 182.48 ?  867  ALA   A O    1 
ATOM   2777 C  CB   . ALA   A 1 175 ? 53.032 -15.960 47.388 1.00 181.40 ?  867  ALA   A CB   1 
ATOM   2778 H  H    . ALA   A 1 175 ? 55.463 -15.657 47.918 1.00 185.93 ?  867  ALA   A H    1 
ATOM   2779 H  HA   . ALA   A 1 175 ? 53.759 -17.949 47.554 1.00 185.68 ?  867  ALA   A HA   1 
ATOM   2780 H  HB1  . ALA   A 1 175 ? 52.034 -16.252 47.057 1.00 183.40 ?  867  ALA   A HB1  1 
ATOM   2781 H  HB2  . ALA   A 1 175 ? 52.975 -15.801 48.466 1.00 183.40 ?  867  ALA   A HB2  1 
ATOM   2782 H  HB3  . ALA   A 1 175 ? 53.268 -15.001 46.928 1.00 183.40 ?  867  ALA   A HB3  1 
ATOM   2783 N  N    . GLU   A 1 176 ? 55.078 -18.073 45.142 1.00 184.25 ?  868  GLU   A N    1 
ATOM   2784 C  CA   . GLU   A 1 176 ? 55.273 -18.469 43.757 1.00 184.95 ?  868  GLU   A CA   1 
ATOM   2785 C  C    . GLU   A 1 176 ? 54.697 -19.867 43.547 1.00 186.06 ?  868  GLU   A C    1 
ATOM   2786 O  O    . GLU   A 1 176 ? 55.339 -20.802 43.067 1.00 186.28 ?  868  GLU   A O    1 
ATOM   2787 C  CB   . GLU   A 1 176 ? 56.770 -18.395 43.437 1.00 182.74 ?  868  GLU   A CB   1 
ATOM   2788 C  CG   . GLU   A 1 176 ? 57.091 -18.035 41.990 1.00 180.27 ?  868  GLU   A CG   1 
ATOM   2789 C  CD   . GLU   A 1 176 ? 56.706 -16.595 41.723 1.00 180.20 ?  868  GLU   A CD   1 
ATOM   2790 O  OE1  . GLU   A 1 176 ? 55.642 -16.359 41.112 1.00 179.16 ?  868  GLU   A OE1  1 
ATOM   2791 O  OE2  . GLU   A 1 176 ? 57.458 -15.685 42.130 1.00 179.29 -1 868  GLU   A OE2  1 
ATOM   2792 H  H    . GLU   A 1 176 ? 55.699 -18.451 45.854 1.00 186.25 ?  868  GLU   A H    1 
ATOM   2793 H  HA   . GLU   A 1 176 ? 54.721 -17.802 43.095 1.00 186.95 ?  868  GLU   A HA   1 
ATOM   2794 H  HB2  . GLU   A 1 176 ? 57.244 -17.648 44.077 1.00 184.74 ?  868  GLU   A HB2  1 
ATOM   2795 H  HB3  . GLU   A 1 176 ? 57.274 -19.326 43.704 1.00 184.74 ?  868  GLU   A HB3  1 
ATOM   2796 H  HG2  . GLU   A 1 176 ? 58.160 -18.154 41.812 1.00 182.27 ?  868  GLU   A HG2  1 
ATOM   2797 H  HG3  . GLU   A 1 176 ? 56.563 -18.693 41.301 1.00 182.27 ?  868  GLU   A HG3  1 
ATOM   2798 N  N    . TYR   A 1 177 ? 53.451 -19.987 43.976 1.00 185.78 ?  869  TYR   A N    1 
ATOM   2799 C  CA   . TYR   A 1 177 ? 52.643 -21.184 43.803 1.00 185.14 ?  869  TYR   A CA   1 
ATOM   2800 C  C    . TYR   A 1 177 ? 51.192 -20.749 43.640 1.00 183.43 ?  869  TYR   A C    1 
ATOM   2801 O  O    . TYR   A 1 177 ? 50.260 -21.416 44.093 1.00 180.92 ?  869  TYR   A O    1 
ATOM   2802 C  CB   . TYR   A 1 177 ? 52.900 -22.212 44.910 1.00 184.65 ?  869  TYR   A CB   1 
ATOM   2803 C  CG   . TYR   A 1 177 ? 52.841 -23.682 44.516 1.00 183.19 ?  869  TYR   A CG   1 
ATOM   2804 C  CD1  . TYR   A 1 177 ? 51.611 -24.375 44.531 1.00 180.72 ?  869  TYR   A CD1  1 
ATOM   2805 C  CD2  . TYR   A 1 177 ? 54.022 -24.359 44.146 1.00 182.68 ?  869  TYR   A CD2  1 
ATOM   2806 C  CE1  . TYR   A 1 177 ? 51.565 -25.738 44.177 1.00 178.57 ?  869  TYR   A CE1  1 
ATOM   2807 C  CE2  . TYR   A 1 177 ? 53.975 -25.722 43.796 1.00 180.07 ?  869  TYR   A CE2  1 
ATOM   2808 C  CZ   . TYR   A 1 177 ? 52.746 -26.412 43.811 1.00 178.56 ?  869  TYR   A CZ   1 
ATOM   2809 O  OH   . TYR   A 1 177 ? 52.698 -27.732 43.471 1.00 175.85 ?  869  TYR   A OH   1 
ATOM   2810 H  H    . TYR   A 1 177 ? 53.007 -19.162 44.356 1.00 187.78 ?  869  TYR   A H    1 
ATOM   2811 H  HA   . TYR   A 1 177 ? 52.918 -21.649 42.853 1.00 187.14 ?  869  TYR   A HA   1 
ATOM   2812 H  HB2  . TYR   A 1 177 ? 53.889 -22.048 45.339 1.00 186.65 ?  869  TYR   A HB2  1 
ATOM   2813 H  HB3  . TYR   A 1 177 ? 52.214 -22.050 45.743 1.00 186.65 ?  869  TYR   A HB3  1 
ATOM   2814 H  HD1  . TYR   A 1 177 ? 50.704 -23.862 44.814 1.00 182.72 ?  869  TYR   A HD1  1 
ATOM   2815 H  HD2  . TYR   A 1 177 ? 54.966 -23.831 44.133 1.00 184.68 ?  869  TYR   A HD2  1 
ATOM   2816 H  HE1  . TYR   A 1 177 ? 50.624 -26.267 44.187 1.00 180.57 ?  869  TYR   A HE1  1 
ATOM   2817 H  HE2  . TYR   A 1 177 ? 54.881 -26.236 43.518 1.00 182.07 ?  869  TYR   A HE2  1 
ATOM   2818 H  HH   . TYR   A 1 177 ? 53.547 -28.089 43.246 1.00 177.85 ?  869  TYR   A HH   1 
ATOM   2819 N  N    . HIS   A 1 178 ? 51.007 -19.570 43.046 1.00 181.96 ?  870  HIS   A N    1 
ATOM   2820 C  CA   . HIS   A 1 178 ? 49.708 -18.923 43.007 1.00 181.46 ?  870  HIS   A CA   1 
ATOM   2821 C  C    . HIS   A 1 178 ? 49.501 -18.168 41.713 1.00 181.40 ?  870  HIS   A C    1 
ATOM   2822 O  O    . HIS   A 1 178 ? 50.444 -17.882 40.969 1.00 179.14 ?  870  HIS   A O    1 
ATOM   2823 C  CB   . HIS   A 1 178 ? 49.383 -18.137 44.271 1.00 181.59 ?  870  HIS   A CB   1 
ATOM   2824 C  CG   . HIS   A 1 178 ? 48.014 -18.449 44.826 1.00 179.97 ?  870  HIS   A CG   1 
ATOM   2825 N  ND1  . HIS   A 1 178 ? 46.819 -18.157 44.135 1.00 178.12 ?  870  HIS   A ND1  1 
ATOM   2826 C  CD2  . HIS   A 1 178 ? 47.671 -19.050 46.045 1.00 178.83 ?  870  HIS   A CD2  1 
ATOM   2827 C  CE1  . HIS   A 1 178 ? 45.861 -18.568 44.928 1.00 177.00 ?  870  HIS   A CE1  1 
ATOM   2828 N  NE2  . HIS   A 1 178 ? 46.283 -19.098 46.050 1.00 177.39 ?  870  HIS   A NE2  1 
ATOM   2829 H  H    . HIS   A 1 178 ? 51.775 -19.110 42.573 1.00 183.96 ?  870  HIS   A H    1 
ATOM   2830 H  HA   . HIS   A 1 178 ? 48.966 -19.715 42.949 1.00 183.46 ?  870  HIS   A HA   1 
ATOM   2831 H  HB2  . HIS   A 1 178 ? 50.109 -18.355 45.055 1.00 183.59 ?  870  HIS   A HB2  1 
ATOM   2832 H  HB3  . HIS   A 1 178 ? 49.457 -17.061 44.098 1.00 183.59 ?  870  HIS   A HB3  1 
ATOM   2833 H  HD2  . HIS   A 1 178 ? 48.275 -19.424 46.861 1.00 180.83 ?  870  HIS   A HD2  1 
ATOM   2834 H  HE1  . HIS   A 1 178 ? 44.812 -18.480 44.678 1.00 179.00 ?  870  HIS   A HE1  1 
ATOM   2835 H  HE2  . HIS   A 1 178 ? 45.700 -19.471 46.790 1.00 179.39 ?  870  HIS   A HE2  1 
ATOM   2836 N  N    . ALA   A 1 179 ? 48.238 -17.881 41.429 1.00 182.47 ?  871  ALA   A N    1 
ATOM   2837 C  CA   . ALA   A 1 179 ? 47.837 -17.338 40.138 1.00 184.56 ?  871  ALA   A CA   1 
ATOM   2838 C  C    . ALA   A 1 179 ? 47.861 -15.813 40.143 1.00 186.84 ?  871  ALA   A C    1 
ATOM   2839 O  O    . ALA   A 1 179 ? 46.837 -15.139 39.980 1.00 187.08 ?  871  ALA   A O    1 
ATOM   2840 C  CB   . ALA   A 1 179 ? 46.435 -17.835 39.814 1.00 181.50 ?  871  ALA   A CB   1 
ATOM   2841 H  H    . ALA   A 1 179 ? 47.543 -18.003 42.162 1.00 184.47 ?  871  ALA   A H    1 
ATOM   2842 H  HA   . ALA   A 1 179 ? 48.505 -17.680 39.343 1.00 186.56 ?  871  ALA   A HA   1 
ATOM   2843 H  HB1  . ALA   A 1 179 ? 45.711 -17.529 40.571 1.00 183.50 ?  871  ALA   A HB1  1 
ATOM   2844 H  HB2  . ALA   A 1 179 ? 46.091 -17.448 38.855 1.00 183.50 ?  871  ALA   A HB2  1 
ATOM   2845 H  HB3  . ALA   A 1 179 ? 46.405 -18.921 39.744 1.00 183.50 ?  871  ALA   A HB3  1 
ATOM   2846 N  N    . GLU   A 1 180 ? 49.058 -15.273 40.335 1.00 188.55 ?  872  GLU   A N    1 
ATOM   2847 C  CA   . GLU   A 1 180 ? 49.272 -13.831 40.383 1.00 187.34 ?  872  GLU   A CA   1 
ATOM   2848 C  C    . GLU   A 1 180 ? 49.005 -13.198 39.020 1.00 186.96 ?  872  GLU   A C    1 
ATOM   2849 O  O    . GLU   A 1 180 ? 49.754 -13.403 38.067 1.00 188.24 ?  872  GLU   A O    1 
ATOM   2850 C  CB   . GLU   A 1 180 ? 50.718 -13.541 40.808 1.00 185.72 ?  872  GLU   A CB   1 
ATOM   2851 C  CG   . GLU   A 1 180 ? 51.161 -14.113 42.165 1.00 182.80 ?  872  GLU   A CG   1 
ATOM   2852 C  CD   . GLU   A 1 180 ? 50.732 -13.190 43.286 1.00 180.97 ?  872  GLU   A CD   1 
ATOM   2853 O  OE1  . GLU   A 1 180 ? 49.517 -12.957 43.447 1.00 178.59 ?  872  GLU   A OE1  1 
ATOM   2854 O  OE2  . GLU   A 1 180 ? 51.609 -12.689 44.020 1.00 178.34 -1 872  GLU   A OE2  1 
ATOM   2855 H  H    . GLU   A 1 180 ? 49.849 -15.892 40.469 1.00 190.55 ?  872  GLU   A H    1 
ATOM   2856 H  HA   . GLU   A 1 180 ? 48.586 -13.398 41.113 1.00 189.34 ?  872  GLU   A HA   1 
ATOM   2857 H  HB2  . GLU   A 1 180 ? 51.396 -13.942 40.054 1.00 187.72 ?  872  GLU   A HB2  1 
ATOM   2858 H  HB3  . GLU   A 1 180 ? 50.891 -12.462 40.789 1.00 187.72 ?  872  GLU   A HB3  1 
ATOM   2859 H  HG2  . GLU   A 1 180 ? 50.748 -15.107 42.329 1.00 184.80 ?  872  GLU   A HG2  1 
ATOM   2860 H  HG3  . GLU   A 1 180 ? 52.246 -14.214 42.186 1.00 184.80 ?  872  GLU   A HG3  1 
ATOM   2861 N  N    . GLY   A 1 181 ? 47.883 -12.505 38.885 1.00 184.69 ?  873  GLY   A N    1 
ATOM   2862 C  CA   . GLY   A 1 181 ? 47.576 -11.924 37.580 1.00 181.84 ?  873  GLY   A CA   1 
ATOM   2863 C  C    . GLY   A 1 181 ? 46.923 -12.893 36.610 1.00 180.06 ?  873  GLY   A C    1 
ATOM   2864 O  O    . GLY   A 1 181 ? 46.874 -12.635 35.405 1.00 180.08 ?  873  GLY   A O    1 
ATOM   2865 H  H    . GLY   A 1 181 ? 47.228 -12.429 39.649 1.00 186.69 ?  873  GLY   A H    1 
ATOM   2866 H  HA2  . GLY   A 1 181 ? 46.880 -11.100 37.736 1.00 183.84 ?  873  GLY   A HA2  1 
ATOM   2867 H  HA3  . GLY   A 1 181 ? 48.457 -11.476 37.116 1.00 183.84 ?  873  GLY   A HA3  1 
ATOM   2868 N  N    . GLY   A 1 182 ? 46.499 -14.042 37.124 1.00 177.66 ?  874  GLY   A N    1 
ATOM   2869 C  CA   . GLY   A 1 182 ? 45.946 -15.093 36.294 1.00 174.14 ?  874  GLY   A CA   1 
ATOM   2870 C  C    . GLY   A 1 182 ? 46.860 -16.295 36.217 1.00 171.01 ?  874  GLY   A C    1 
ATOM   2871 O  O    . GLY   A 1 182 ? 47.957 -16.334 36.781 1.00 170.71 ?  874  GLY   A O    1 
ATOM   2872 H  H    . GLY   A 1 182 ? 46.686 -14.249 38.100 1.00 179.66 ?  874  GLY   A H    1 
ATOM   2873 H  HA2  . GLY   A 1 182 ? 45.005 -15.405 36.748 1.00 176.14 ?  874  GLY   A HA2  1 
ATOM   2874 H  HA3  . GLY   A 1 182 ? 45.699 -14.760 35.283 1.00 176.14 ?  874  GLY   A HA3  1 
ATOM   2875 N  N    . LYS   A 1 183 ? 46.398 -17.277 35.462 1.00 164.93 ?  875  LYS   A N    1 
ATOM   2876 C  CA   . LYS   A 1 183 ? 47.200 -18.440 35.112 1.00 153.48 ?  875  LYS   A CA   1 
ATOM   2877 C  C    . LYS   A 1 183 ? 46.845 -18.821 33.680 1.00 139.27 ?  875  LYS   A C    1 
ATOM   2878 O  O    . LYS   A 1 183 ? 46.495 -19.966 33.390 1.00 141.93 ?  875  LYS   A O    1 
ATOM   2879 C  CB   . LYS   A 1 183 ? 47.064 -19.556 36.154 1.00 158.57 ?  875  LYS   A CB   1 
ATOM   2880 C  CG   . LYS   A 1 183 ? 48.119 -20.655 36.032 1.00 161.64 ?  875  LYS   A CG   1 
ATOM   2881 C  CD   . LYS   A 1 183 ? 47.641 -22.046 36.435 1.00 163.74 ?  875  LYS   A CD   1 
ATOM   2882 C  CE   . LYS   A 1 183 ? 46.726 -22.708 35.413 1.00 164.19 ?  875  LYS   A CE   1 
ATOM   2883 N  NZ   . LYS   A 1 183 ? 46.300 -24.040 35.874 1.00 164.51 1  875  LYS   A NZ   1 
ATOM   2884 H  H    . LYS   A 1 183 ? 45.492 -17.194 35.026 1.00 166.93 ?  875  LYS   A H    1 
ATOM   2885 H  HA   . LYS   A 1 183 ? 48.254 -18.153 35.077 1.00 155.48 ?  875  LYS   A HA   1 
ATOM   2886 H  HB2  . LYS   A 1 183 ? 47.133 -19.135 37.158 1.00 160.57 ?  875  LYS   A HB2  1 
ATOM   2887 H  HB3  . LYS   A 1 183 ? 46.059 -19.972 36.084 1.00 160.57 ?  875  LYS   A HB3  1 
ATOM   2888 H  HG2  . LYS   A 1 183 ? 48.485 -20.703 35.013 1.00 163.64 ?  875  LYS   A HG2  1 
ATOM   2889 H  HG3  . LYS   A 1 183 ? 48.991 -20.370 36.623 1.00 163.64 ?  875  LYS   A HG3  1 
ATOM   2890 H  HD2  . LYS   A 1 183 ? 48.513 -22.689 36.565 1.00 165.74 ?  875  LYS   A HD2  1 
ATOM   2891 H  HD3  . LYS   A 1 183 ? 47.143 -21.998 37.403 1.00 165.74 ?  875  LYS   A HD3  1 
ATOM   2892 H  HE2  . LYS   A 1 183 ? 45.836 -22.104 35.238 1.00 166.19 ?  875  LYS   A HE2  1 
ATOM   2893 H  HE3  . LYS   A 1 183 ? 47.233 -22.814 34.453 1.00 166.19 ?  875  LYS   A HE3  1 
ATOM   2894 H  HZ1  . LYS   A 1 183 ? 47.101 -24.659 35.891 1.00 166.51 ?  875  LYS   A HZ1  1 
ATOM   2895 H  HZ2  . LYS   A 1 183 ? 45.914 -23.969 36.803 1.00 166.51 ?  875  LYS   A HZ2  1 
ATOM   2896 H  HZ3  . LYS   A 1 183 ? 45.602 -24.411 35.248 1.00 166.51 ?  875  LYS   A HZ3  1 
ATOM   2897 N  N    . VAL   A 1 184 ? 46.844 -17.811 32.814 1.00 117.62 ?  876  VAL   A N    1 
ATOM   2898 C  CA   . VAL   A 1 184 ? 46.108 -17.879 31.556 1.00 101.48 ?  876  VAL   A CA   1 
ATOM   2899 C  C    . VAL   A 1 184 ? 46.903 -17.964 30.244 1.00 84.10  ?  876  VAL   A C    1 
ATOM   2900 O  O    . VAL   A 1 184 ? 46.340 -18.531 29.301 1.00 83.31  ?  876  VAL   A O    1 
ATOM   2901 C  CB   . VAL   A 1 184 ? 45.046 -16.768 31.502 1.00 102.03 ?  876  VAL   A CB   1 
ATOM   2902 C  CG1  . VAL   A 1 184 ? 43.962 -16.953 32.556 1.00 105.55 ?  876  VAL   A CG1  1 
ATOM   2903 C  CG2  . VAL   A 1 184 ? 45.609 -15.354 31.580 1.00 107.11 ?  876  VAL   A CG2  1 
ATOM   2904 H  H    . VAL   A 1 184 ? 47.173 -16.910 33.123 1.00 119.62 ?  876  VAL   A H    1 
ATOM   2905 H  HA   . VAL   A 1 184 ? 45.532 -18.807 31.533 1.00 103.48 ?  876  VAL   A HA   1 
ATOM   2906 H  HB   . VAL   A 1 184 ? 44.538 -16.852 30.538 1.00 104.03 ?  876  VAL   A HB   1 
ATOM   2907 H  HG11 . VAL   A 1 184 ? 43.147 -16.244 32.407 1.00 107.55 ?  876  VAL   A HG11 1 
ATOM   2908 H  HG12 . VAL   A 1 184 ? 43.528 -17.953 32.508 1.00 107.55 ?  876  VAL   A HG12 1 
ATOM   2909 H  HG13 . VAL   A 1 184 ? 44.341 -16.804 33.565 1.00 107.55 ?  876  VAL   A HG13 1 
ATOM   2910 H  HG21 . VAL   A 1 184 ? 44.808 -14.616 31.527 1.00 109.11 ?  876  VAL   A HG21 1 
ATOM   2911 H  HG22 . VAL   A 1 184 ? 46.155 -15.172 32.505 1.00 109.11 ?  876  VAL   A HG22 1 
ATOM   2912 H  HG23 . VAL   A 1 184 ? 46.274 -15.143 30.742 1.00 109.11 ?  876  VAL   A HG23 1 
ATOM   2913 N  N    . PRO   A 1 185 ? 48.150 -17.474 30.084 1.00 67.09  ?  877  PRO   A N    1 
ATOM   2914 C  CA   . PRO   A 1 185 ? 48.857 -17.581 28.796 1.00 64.83  ?  877  PRO   A CA   1 
ATOM   2915 C  C    . PRO   A 1 185 ? 49.490 -18.964 28.569 1.00 62.02  ?  877  PRO   A C    1 
ATOM   2916 O  O    . PRO   A 1 185 ? 50.698 -19.109 28.362 1.00 62.16  ?  877  PRO   A O    1 
ATOM   2917 C  CB   . PRO   A 1 185 ? 49.883 -16.457 28.858 1.00 55.89  ?  877  PRO   A CB   1 
ATOM   2918 C  CG   . PRO   A 1 185 ? 50.218 -16.327 30.343 1.00 60.85  ?  877  PRO   A CG   1 
ATOM   2919 C  CD   . PRO   A 1 185 ? 48.914 -16.688 31.059 1.00 59.63  ?  877  PRO   A CD   1 
ATOM   2920 H  HA   . PRO   A 1 185 ? 48.184 -17.388 27.958 1.00 66.83  ?  877  PRO   A HA   1 
ATOM   2921 H  HB2  . PRO   A 1 185 ? 50.770 -16.611 28.241 1.00 57.89  ?  877  PRO   A HB2  1 
ATOM   2922 H  HB3  . PRO   A 1 185 ? 49.423 -15.530 28.516 1.00 57.89  ?  877  PRO   A HB3  1 
ATOM   2923 H  HG2  . PRO   A 1 185 ? 50.996 -17.047 30.603 1.00 62.85  ?  877  PRO   A HG2  1 
ATOM   2924 H  HG3  . PRO   A 1 185 ? 50.591 -15.336 30.608 1.00 62.85  ?  877  PRO   A HG3  1 
ATOM   2925 H  HD2  . PRO   A 1 185 ? 49.150 -17.256 31.958 1.00 61.63  ?  877  PRO   A HD2  1 
ATOM   2926 H  HD3  . PRO   A 1 185 ? 48.376 -15.785 31.342 1.00 61.63  ?  877  PRO   A HD3  1 
ATOM   2927 N  N    . ILE   A 1 186 ? 48.650 -19.992 28.645 1.00 48.11  ?  878  ILE   A N    1 
ATOM   2928 C  CA   . ILE   A 1 186 ? 49.055 -21.391 28.775 1.00 53.64  ?  878  ILE   A CA   1 
ATOM   2929 C  C    . ILE   A 1 186 ? 49.948 -21.910 27.662 1.00 54.03  ?  878  ILE   A C    1 
ATOM   2930 O  O    . ILE   A 1 186 ? 50.846 -22.715 27.907 1.00 48.85  ?  878  ILE   A O    1 
ATOM   2931 C  CB   . ILE   A 1 186 ? 47.809 -22.263 29.028 1.00 56.41  ?  878  ILE   A CB   1 
ATOM   2932 C  CG1  . ILE   A 1 186 ? 47.272 -22.003 30.439 1.00 58.34  ?  878  ILE   A CG1  1 
ATOM   2933 C  CG2  . ILE   A 1 186 ? 48.007 -23.766 28.824 1.00 46.05  ?  878  ILE   A CG2  1 
ATOM   2934 C  CD1  . ILE   A 1 186 ? 45.790 -22.273 30.597 1.00 65.82  ?  878  ILE   A CD1  1 
ATOM   2935 H  H    . ILE   A 1 186 ? 47.670 -19.768 28.778 1.00 50.11  ?  878  ILE   A H    1 
ATOM   2936 H  HA   . ILE   A 1 186 ? 49.672 -21.459 29.668 1.00 55.64  ?  878  ILE   A HA   1 
ATOM   2937 H  HB   . ILE   A 1 186 ? 47.052 -21.948 28.307 1.00 58.41  ?  878  ILE   A HB   1 
ATOM   2938 H  HG12 . ILE   A 1 186 ? 47.836 -22.590 31.166 1.00 60.34  ?  878  ILE   A HG12 1 
ATOM   2939 H  HG13 . ILE   A 1 186 ? 47.438 -20.965 30.732 1.00 60.34  ?  878  ILE   A HG13 1 
ATOM   2940 H  HG21 . ILE   A 1 186 ? 47.121 -24.335 29.103 1.00 48.05  ?  878  ILE   A HG21 1 
ATOM   2941 H  HG22 . ILE   A 1 186 ? 48.218 -24.019 27.784 1.00 48.05  ?  878  ILE   A HG22 1 
ATOM   2942 H  HG23 . ILE   A 1 186 ? 48.829 -24.136 29.431 1.00 48.05  ?  878  ILE   A HG23 1 
ATOM   2943 H  HD11 . ILE   A 1 186 ? 45.467 -22.050 31.614 1.00 67.82  ?  878  ILE   A HD11 1 
ATOM   2944 H  HD12 . ILE   A 1 186 ? 45.205 -21.642 29.926 1.00 67.82  ?  878  ILE   A HD12 1 
ATOM   2945 H  HD13 . ILE   A 1 186 ? 45.535 -23.312 30.391 1.00 67.82  ?  878  ILE   A HD13 1 
ATOM   2946 N  N    . LYS   A 1 187 ? 49.737 -21.418 26.452 1.00 43.75  ?  879  LYS   A N    1 
ATOM   2947 C  CA   . LYS   A 1 187 ? 50.554 -21.847 25.330 1.00 52.78  ?  879  LYS   A CA   1 
ATOM   2948 C  C    . LYS   A 1 187 ? 51.976 -21.266 25.312 1.00 53.22  ?  879  LYS   A C    1 
ATOM   2949 O  O    . LYS   A 1 187 ? 52.836 -21.758 24.581 1.00 58.22  ?  879  LYS   A O    1 
ATOM   2950 C  CB   . LYS   A 1 187 ? 49.790 -21.546 24.050 1.00 44.58  ?  879  LYS   A CB   1 
ATOM   2951 C  CG   . LYS   A 1 187 ? 48.583 -22.480 23.897 1.00 38.18  ?  879  LYS   A CG   1 
ATOM   2952 C  CD   . LYS   A 1 187 ? 47.652 -22.076 22.766 1.00 42.35  ?  879  LYS   A CD   1 
ATOM   2953 C  CE   . LYS   A 1 187 ? 46.595 -23.131 22.452 1.00 52.19  ?  879  LYS   A CE   1 
ATOM   2954 N  NZ   . LYS   A 1 187 ? 45.889 -22.833 21.194 1.00 55.93  1  879  LYS   A NZ   1 
ATOM   2955 H  H    . LYS   A 1 187 ? 48.982 -20.747 26.299 1.00 45.75  ?  879  LYS   A H    1 
ATOM   2956 H  HA   . LYS   A 1 187 ? 50.690 -22.931 25.376 1.00 54.78  ?  879  LYS   A HA   1 
ATOM   2957 H  HB2  . LYS   A 1 187 ? 49.466 -20.506 24.047 1.00 46.58  ?  879  LYS   A HB2  1 
ATOM   2958 H  HB3  . LYS   A 1 187 ? 50.443 -21.650 23.183 1.00 46.58  ?  879  LYS   A HB3  1 
ATOM   2959 H  HG2  . LYS   A 1 187 ? 48.945 -23.497 23.736 1.00 40.18  ?  879  LYS   A HG2  1 
ATOM   2960 H  HG3  . LYS   A 1 187 ? 48.002 -22.513 24.820 1.00 40.18  ?  879  LYS   A HG3  1 
ATOM   2961 H  HD2  . LYS   A 1 187 ? 47.166 -21.132 23.012 1.00 44.35  ?  879  LYS   A HD2  1 
ATOM   2962 H  HD3  . LYS   A 1 187 ? 48.246 -21.875 21.882 1.00 44.35  ?  879  LYS   A HD3  1 
ATOM   2963 H  HE2  . LYS   A 1 187 ? 47.044 -24.117 22.350 1.00 54.19  ?  879  LYS   A HE2  1 
ATOM   2964 H  HE3  . LYS   A 1 187 ? 45.868 -23.202 23.262 1.00 54.19  ?  879  LYS   A HE3  1 
ATOM   2965 H  HZ1  . LYS   A 1 187 ? 45.202 -23.559 21.039 1.00 57.93  ?  879  LYS   A HZ1  1 
ATOM   2966 H  HZ2  . LYS   A 1 187 ? 45.436 -21.933 21.249 1.00 57.93  ?  879  LYS   A HZ2  1 
ATOM   2967 H  HZ3  . LYS   A 1 187 ? 46.554 -22.843 20.434 1.00 57.93  ?  879  LYS   A HZ3  1 
ATOM   2968 N  N    . TRP   A 1 188 ? 52.241 -20.277 26.162 1.00 45.97  ?  880  TRP   A N    1 
ATOM   2969 C  CA   . TRP   A 1 188 ? 53.590 -19.741 26.342 1.00 36.08  ?  880  TRP   A CA   1 
ATOM   2970 C  C    . TRP   A 1 188 ? 54.207 -20.182 27.653 1.00 32.54  ?  880  TRP   A C    1 
ATOM   2971 O  O    . TRP   A 1 188 ? 55.347 -19.830 27.961 1.00 45.02  ?  880  TRP   A O    1 
ATOM   2972 C  CB   . TRP   A 1 188 ? 53.577 -18.213 26.288 1.00 35.12  ?  880  TRP   A CB   1 
ATOM   2973 C  CG   . TRP   A 1 188 ? 53.357 -17.682 24.909 1.00 31.64  ?  880  TRP   A CG   1 
ATOM   2974 C  CD1  . TRP   A 1 188 ? 54.314 -17.168 24.109 1.00 33.68  ?  880  TRP   A CD1  1 
ATOM   2975 C  CD2  . TRP   A 1 188 ? 52.118 -17.622 24.139 1.00 38.03  ?  880  TRP   A CD2  1 
ATOM   2976 N  NE1  . TRP   A 1 188 ? 53.763 -16.816 22.897 1.00 40.93  ?  880  TRP   A NE1  1 
ATOM   2977 C  CE2  . TRP   A 1 188 ? 52.416 -17.088 22.848 1.00 33.97  ?  880  TRP   A CE2  1 
ATOM   2978 C  CE3  . TRP   A 1 188 ? 50.766 -17.972 24.389 1.00 42.29  ?  880  TRP   A CE3  1 
ATOM   2979 C  CZ2  . TRP   A 1 188 ? 51.444 -16.934 21.854 1.00 37.36  ?  880  TRP   A CZ2  1 
ATOM   2980 C  CZ3  . TRP   A 1 188 ? 49.779 -17.811 23.390 1.00 29.15  ?  880  TRP   A CZ3  1 
ATOM   2981 C  CH2  . TRP   A 1 188 ? 50.121 -17.298 22.123 1.00 38.26  ?  880  TRP   A CH2  1 
ATOM   2982 H  H    . TRP   A 1 188 ? 51.516 -19.941 26.788 1.00 47.97  ?  880  TRP   A H    1 
ATOM   2983 H  HA   . TRP   A 1 188 ? 54.272 -20.079 25.563 1.00 38.08  ?  880  TRP   A HA   1 
ATOM   2984 H  HB2  . TRP   A 1 188 ? 52.818 -17.802 26.955 1.00 37.12  ?  880  TRP   A HB2  1 
ATOM   2985 H  HB3  . TRP   A 1 188 ? 54.529 -17.803 26.631 1.00 37.12  ?  880  TRP   A HB3  1 
ATOM   2986 H  HD1  . TRP   A 1 188 ? 55.356 -17.074 24.386 1.00 35.68  ?  880  TRP   A HD1  1 
ATOM   2987 H  HE1  . TRP   A 1 188 ? 54.319 -16.433 22.132 1.00 42.93  ?  880  TRP   A HE1  1 
ATOM   2988 H  HE3  . TRP   A 1 188 ? 50.489 -18.375 25.352 1.00 44.29  ?  880  TRP   A HE3  1 
ATOM   2989 H  HZ2  . TRP   A 1 188 ? 51.711 -16.536 20.887 1.00 39.36  ?  880  TRP   A HZ2  1 
ATOM   2990 H  HZ3  . TRP   A 1 188 ? 48.756 -18.088 23.596 1.00 31.15  ?  880  TRP   A HZ3  1 
ATOM   2991 H  HH2  . TRP   A 1 188 ? 49.362 -17.182 21.363 1.00 40.26  ?  880  TRP   A HH2  1 
ATOM   2992 N  N    . MET   A 1 189 ? 53.452 -20.917 28.458 1.00 44.51  ?  881  MET   A N    1 
ATOM   2993 C  CA   . MET   A 1 189 ? 53.873 -21.175 29.825 1.00 41.71  ?  881  MET   A CA   1 
ATOM   2994 C  C    . MET   A 1 189 ? 54.673 -22.454 29.906 1.00 32.95  ?  881  MET   A C    1 
ATOM   2995 O  O    . MET   A 1 189 ? 54.389 -23.448 29.231 1.00 37.58  ?  881  MET   A O    1 
ATOM   2996 C  CB   . MET   A 1 189 ? 52.642 -21.312 30.721 1.00 45.94  ?  881  MET   A CB   1 
ATOM   2997 C  CG   . MET   A 1 189 ? 52.170 -19.970 31.283 1.00 64.33  ?  881  MET   A CG   1 
ATOM   2998 S  SD   . MET   A 1 189 ? 50.453 -19.954 31.855 1.00 58.69  ?  881  MET   A SD   1 
ATOM   2999 C  CE   . MET   A 1 189 ? 50.496 -21.180 33.145 1.00 35.49  ?  881  MET   A CE   1 
ATOM   3000 H  H    . MET   A 1 189 ? 52.557 -21.256 28.136 1.00 46.51  ?  881  MET   A H    1 
ATOM   3001 H  HA   . MET   A 1 189 ? 54.488 -20.357 30.209 1.00 43.71  ?  881  MET   A HA   1 
ATOM   3002 H  HB2  . MET   A 1 189 ? 51.842 -21.807 30.174 1.00 47.94  ?  881  MET   A HB2  1 
ATOM   3003 H  HB3  . MET   A 1 189 ? 52.861 -21.968 31.562 1.00 47.94  ?  881  MET   A HB3  1 
ATOM   3004 H  HG2  . MET   A 1 189 ? 52.827 -19.652 32.094 1.00 66.33  ?  881  MET   A HG2  1 
ATOM   3005 H  HG3  . MET   A 1 189 ? 52.251 -19.205 30.509 1.00 66.33  ?  881  MET   A HG3  1 
ATOM   3006 H  HE1  . MET   A 1 189 ? 49.482 -21.528 33.331 1.00 37.49  ?  881  MET   A HE1  1 
ATOM   3007 H  HE2  . MET   A 1 189 ? 51.071 -22.047 32.841 1.00 37.49  ?  881  MET   A HE2  1 
ATOM   3008 H  HE3  . MET   A 1 189 ? 50.919 -20.790 34.068 1.00 37.49  ?  881  MET   A HE3  1 
ATOM   3009 N  N    . ALA   A 1 190 ? 55.620 -22.451 30.832 1.00 34.52  ?  882  ALA   A N    1 
ATOM   3010 C  CA   . ALA   A 1 190 ? 56.282 -23.687 31.187 1.00 33.05  ?  882  ALA   A CA   1 
ATOM   3011 C  C    . ALA   A 1 190 ? 55.333 -24.644 31.883 1.00 51.50  ?  882  ALA   A C    1 
ATOM   3012 O  O    . ALA   A 1 190 ? 54.373 -24.222 32.535 1.00 61.85  ?  882  ALA   A O    1 
ATOM   3013 C  CB   . ALA   A 1 190 ? 57.462 -23.389 32.082 1.00 30.01  ?  882  ALA   A CB   1 
ATOM   3014 H  H    . ALA   A 1 190 ? 55.770 -21.633 31.400 1.00 36.52  ?  882  ALA   A H    1 
ATOM   3015 H  HA   . ALA   A 1 190 ? 56.630 -24.164 30.278 1.00 35.05  ?  882  ALA   A HA   1 
ATOM   3016 H  HB1  . ALA   A 1 190 ? 58.072 -24.280 32.221 1.00 32.01  ?  882  ALA   A HB1  1 
ATOM   3017 H  HB2  . ALA   A 1 190 ? 58.105 -22.634 31.635 1.00 32.01  ?  882  ALA   A HB2  1 
ATOM   3018 H  HB3  . ALA   A 1 190 ? 57.148 -23.032 33.064 1.00 32.01  ?  882  ALA   A HB3  1 
ATOM   3019 N  N    . LEU   A 1 191 ? 55.606 -25.936 31.744 1.00 59.28  ?  883  LEU   A N    1 
ATOM   3020 C  CA   . LEU   A 1 191 ? 54.704 -26.960 32.269 1.00 57.51  ?  883  LEU   A CA   1 
ATOM   3021 C  C    . LEU   A 1 191 ? 54.473 -26.855 33.773 1.00 50.87  ?  883  LEU   A C    1 
ATOM   3022 O  O    . LEU   A 1 191 ? 53.340 -26.956 34.244 1.00 48.68  ?  883  LEU   A O    1 
ATOM   3023 C  CB   . LEU   A 1 191 ? 55.197 -28.355 31.882 1.00 52.12  ?  883  LEU   A CB   1 
ATOM   3024 C  CG   . LEU   A 1 191 ? 54.309 -29.520 32.323 1.00 46.23  ?  883  LEU   A CG   1 
ATOM   3025 C  CD1  . LEU   A 1 191 ? 52.950 -29.503 31.647 1.00 50.97  ?  883  LEU   A CD1  1 
ATOM   3026 C  CD2  . LEU   A 1 191 ? 55.007 -30.845 32.114 1.00 51.47  ?  883  LEU   A CD2  1 
ATOM   3027 H  H    . LEU   A 1 191 ? 56.374 -26.211 31.148 1.00 61.28  ?  883  LEU   A H    1 
ATOM   3028 H  HA   . LEU   A 1 191 ? 53.740 -26.795 31.786 1.00 59.51  ?  883  LEU   A HA   1 
ATOM   3029 H  HB2  . LEU   A 1 191 ? 55.328 -28.403 30.799 1.00 54.12  ?  883  LEU   A HB2  1 
ATOM   3030 H  HB3  . LEU   A 1 191 ? 56.195 -28.494 32.302 1.00 54.12  ?  883  LEU   A HB3  1 
ATOM   3031 H  HG   . LEU   A 1 191 ? 54.142 -29.456 33.397 1.00 48.23  ?  883  LEU   A HG   1 
ATOM   3032 H  HD11 . LEU   A 1 191 ? 52.359 -30.378 31.922 1.00 52.97  ?  883  LEU   A HD11 1 
ATOM   3033 H  HD12 . LEU   A 1 191 ? 52.366 -28.628 31.931 1.00 52.97  ?  883  LEU   A HD12 1 
ATOM   3034 H  HD13 . LEU   A 1 191 ? 53.049 -29.495 30.566 1.00 52.97  ?  883  LEU   A HD13 1 
ATOM   3035 H  HD21 . LEU   A 1 191 ? 54.437 -31.657 32.562 1.00 53.47  ?  883  LEU   A HD21 1 
ATOM   3036 H  HD22 . LEU   A 1 191 ? 55.144 -31.071 31.056 1.00 53.47  ?  883  LEU   A HD22 1 
ATOM   3037 H  HD23 . LEU   A 1 191 ? 55.984 -30.850 32.597 1.00 53.47  ?  883  LEU   A HD23 1 
ATOM   3038 N  N    . GLU   A 1 192 ? 55.539 -26.568 34.511 1.00 41.54  ?  884  GLU   A N    1 
ATOM   3039 C  CA   . GLU   A 1 192 ? 55.436 -26.297 35.937 1.00 54.31  ?  884  GLU   A CA   1 
ATOM   3040 C  C    . GLU   A 1 192 ? 54.569 -25.095 36.309 1.00 56.83  ?  884  GLU   A C    1 
ATOM   3041 O  O    . GLU   A 1 192 ? 53.998 -25.052 37.400 1.00 63.17  ?  884  GLU   A O    1 
ATOM   3042 C  CB   . GLU   A 1 192 ? 56.829 -26.227 36.572 1.00 43.77  ?  884  GLU   A CB   1 
ATOM   3043 C  CG   . GLU   A 1 192 ? 57.683 -24.953 36.380 1.00 64.99  ?  884  GLU   A CG   1 
ATOM   3044 C  CD   . GLU   A 1 192 ? 58.526 -25.036 35.111 1.00 65.30  ?  884  GLU   A CD   1 
ATOM   3045 O  OE1  . GLU   A 1 192 ? 58.244 -25.886 34.238 1.00 49.07  ?  884  GLU   A OE1  1 
ATOM   3046 O  OE2  . GLU   A 1 192 ? 59.481 -24.244 34.976 1.00 54.52  -1 884  GLU   A OE2  1 
ATOM   3047 H  H    . GLU   A 1 192 ? 56.442 -26.443 34.069 1.00 43.54  ?  884  GLU   A H    1 
ATOM   3048 H  HA   . GLU   A 1 192 ? 54.938 -27.168 36.368 1.00 56.31  ?  884  GLU   A HA   1 
ATOM   3049 H  HB2  . GLU   A 1 192 ? 56.674 -26.321 37.647 1.00 45.77  ?  884  GLU   A HB2  1 
ATOM   3050 H  HB3  . GLU   A 1 192 ? 57.398 -27.123 36.319 1.00 45.77  ?  884  GLU   A HB3  1 
ATOM   3051 H  HG2  . GLU   A 1 192 ? 57.065 -24.056 36.353 1.00 66.99  ?  884  GLU   A HG2  1 
ATOM   3052 H  HG3  . GLU   A 1 192 ? 58.367 -24.841 37.222 1.00 66.99  ?  884  GLU   A HG3  1 
ATOM   3053 N  N    . SER   A 1 193 ? 54.416 -24.148 35.396 1.00 50.02  ?  885  SER   A N    1 
ATOM   3054 C  CA   . SER   A 1 193 ? 53.549 -23.008 35.641 1.00 53.90  ?  885  SER   A CA   1 
ATOM   3055 C  C    . SER   A 1 193 ? 52.096 -23.387 35.380 1.00 57.26  ?  885  SER   A C    1 
ATOM   3056 O  O    . SER   A 1 193 ? 51.200 -22.937 36.097 1.00 62.94  ?  885  SER   A O    1 
ATOM   3057 C  CB   . SER   A 1 193 ? 53.909 -21.832 34.729 1.00 53.82  ?  885  SER   A CB   1 
ATOM   3058 O  OG   . SER   A 1 193 ? 55.277 -21.454 34.807 1.00 51.19  ?  885  SER   A OG   1 
ATOM   3059 H  H    . SER   A 1 193 ? 54.862 -24.218 34.489 1.00 52.02  ?  885  SER   A H    1 
ATOM   3060 H  HA   . SER   A 1 193 ? 53.634 -22.675 36.675 1.00 55.90  ?  885  SER   A HA   1 
ATOM   3061 H  HB2  . SER   A 1 193 ? 53.679 -22.050 33.688 1.00 55.82  ?  885  SER   A HB2  1 
ATOM   3062 H  HB3  . SER   A 1 193 ? 53.300 -20.973 35.002 1.00 55.82  ?  885  SER   A HB3  1 
ATOM   3063 H  HG   . SER   A 1 193 ? 55.503 -21.364 35.737 1.00 53.19  ?  885  SER   A HG   1 
ATOM   3064 N  N    . ILE   A 1 194 ? 51.856 -24.246 34.388 1.00 54.29  ?  886  ILE   A N    1 
ATOM   3065 C  CA   . ILE   A 1 194 ? 50.496 -24.710 34.108 1.00 57.00  ?  886  ILE   A CA   1 
ATOM   3066 C  C    . ILE   A 1 194 ? 50.007 -25.648 35.210 1.00 64.08  ?  886  ILE   A C    1 
ATOM   3067 O  O    . ILE   A 1 194 ? 48.868 -25.539 35.668 1.00 67.52  ?  886  ILE   A O    1 
ATOM   3068 C  CB   . ILE   A 1 194 ? 50.375 -25.403 32.731 1.00 52.89  ?  886  ILE   A CB   1 
ATOM   3069 C  CG1  . ILE   A 1 194 ? 50.910 -24.556 31.575 1.00 51.76  ?  886  ILE   A CG1  1 
ATOM   3070 C  CG2  . ILE   A 1 194 ? 48.930 -25.809 32.420 1.00 52.24  ?  886  ILE   A CG2  1 
ATOM   3071 C  CD1  . ILE   A 1 194 ? 51.176 -25.341 30.298 1.00 44.43  ?  886  ILE   A CD1  1 
ATOM   3072 H  H    . ILE   A 1 194 ? 52.632 -24.606 33.841 1.00 56.29  ?  886  ILE   A H    1 
ATOM   3073 H  HA   . ILE   A 1 194 ? 49.830 -23.846 34.102 1.00 59.00  ?  886  ILE   A HA   1 
ATOM   3074 H  HB   . ILE   A 1 194 ? 50.977 -26.314 32.767 1.00 54.89  ?  886  ILE   A HB   1 
ATOM   3075 H  HG12 . ILE   A 1 194 ? 50.229 -23.730 31.364 1.00 53.76  ?  886  ILE   A HG12 1 
ATOM   3076 H  HG13 . ILE   A 1 194 ? 51.857 -24.094 31.846 1.00 53.76  ?  886  ILE   A HG13 1 
ATOM   3077 H  HG21 . ILE   A 1 194 ? 48.825 -26.254 31.433 1.00 54.24  ?  886  ILE   A HG21 1 
ATOM   3078 H  HG22 . ILE   A 1 194 ? 48.542 -26.548 33.121 1.00 54.24  ?  886  ILE   A HG22 1 
ATOM   3079 H  HG23 . ILE   A 1 194 ? 48.264 -24.946 32.450 1.00 54.24  ?  886  ILE   A HG23 1 
ATOM   3080 H  HD11 . ILE   A 1 194 ? 51.565 -24.673 29.535 1.00 46.43  ?  886  ILE   A HD11 1 
ATOM   3081 H  HD12 . ILE   A 1 194 ? 51.927 -26.114 30.455 1.00 46.43  ?  886  ILE   A HD12 1 
ATOM   3082 H  HD13 . ILE   A 1 194 ? 50.292 -25.820 29.883 1.00 46.43  ?  886  ILE   A HD13 1 
ATOM   3083 N  N    . LEU   A 1 195 ? 50.878 -26.558 35.629 1.00 63.23  ?  887  LEU   A N    1 
ATOM   3084 C  CA   . LEU   A 1 195 ? 50.466 -27.582 36.576 1.00 66.11  ?  887  LEU   A CA   1 
ATOM   3085 C  C    . LEU   A 1 195 ? 50.507 -27.107 38.020 1.00 72.44  ?  887  LEU   A C    1 
ATOM   3086 O  O    . LEU   A 1 195 ? 49.683 -27.524 38.834 1.00 74.44  ?  887  LEU   A O    1 
ATOM   3087 C  CB   . LEU   A 1 195 ? 51.403 -28.787 36.484 1.00 68.06  ?  887  LEU   A CB   1 
ATOM   3088 C  CG   . LEU   A 1 195 ? 51.360 -29.586 35.185 1.00 63.68  ?  887  LEU   A CG   1 
ATOM   3089 C  CD1  . LEU   A 1 195 ? 52.378 -30.710 35.248 1.00 59.62  ?  887  LEU   A CD1  1 
ATOM   3090 C  CD2  . LEU   A 1 195 ? 49.983 -30.149 34.884 1.00 48.16  ?  887  LEU   A CD2  1 
ATOM   3091 H  H    . LEU   A 1 195 ? 51.786 -26.635 35.174 1.00 65.23  ?  887  LEU   A H    1 
ATOM   3092 H  HA   . LEU   A 1 195 ? 49.444 -27.907 36.373 1.00 68.11  ?  887  LEU   A HA   1 
ATOM   3093 H  HB2  . LEU   A 1 195 ? 52.429 -28.453 36.652 1.00 70.06  ?  887  LEU   A HB2  1 
ATOM   3094 H  HB3  . LEU   A 1 195 ? 51.189 -29.474 37.306 1.00 70.06  ?  887  LEU   A HB3  1 
ATOM   3095 H  HG   . LEU   A 1 195 ? 51.640 -28.934 34.358 1.00 65.68  ?  887  LEU   A HG   1 
ATOM   3096 H  HD11 . LEU   A 1 195 ? 52.420 -31.262 34.307 1.00 61.62  ?  887  LEU   A HD11 1 
ATOM   3097 H  HD12 . LEU   A 1 195 ? 53.381 -30.331 35.449 1.00 61.62  ?  887  LEU   A HD12 1 
ATOM   3098 H  HD13 . LEU   A 1 195 ? 52.137 -31.425 36.035 1.00 61.62  ?  887  LEU   A HD13 1 
ATOM   3099 H  HD21 . LEU   A 1 195 ? 50.016 -30.856 34.054 1.00 50.16  ?  887  LEU   A HD21 1 
ATOM   3100 H  HD22 . LEU   A 1 195 ? 49.576 -30.685 35.742 1.00 50.16  ?  887  LEU   A HD22 1 
ATOM   3101 H  HD23 . LEU   A 1 195 ? 49.275 -29.366 34.610 1.00 50.16  ?  887  LEU   A HD23 1 
ATOM   3102 N  N    . HIS   A 1 196 ? 51.481 -26.265 38.338 1.00 71.94  ?  888  HIS   A N    1 
ATOM   3103 C  CA   . HIS   A 1 196 ? 51.815 -26.001 39.737 1.00 66.75  ?  888  HIS   A CA   1 
ATOM   3104 C  C    . HIS   A 1 196 ? 51.830 -24.527 40.083 1.00 70.78  ?  888  HIS   A C    1 
ATOM   3105 O  O    . HIS   A 1 196 ? 51.898 -24.170 41.255 1.00 70.44  ?  888  HIS   A O    1 
ATOM   3106 C  CB   . HIS   A 1 196 ? 53.139 -26.648 40.119 1.00 72.11  ?  888  HIS   A CB   1 
ATOM   3107 C  CG   . HIS   A 1 196 ? 53.283 -28.102 39.755 1.00 86.84  ?  888  HIS   A CG   1 
ATOM   3108 N  ND1  . HIS   A 1 196 ? 52.446 -29.095 40.249 1.00 80.34  ?  888  HIS   A ND1  1 
ATOM   3109 C  CD2  . HIS   A 1 196 ? 54.181 -28.770 38.922 1.00 93.63  ?  888  HIS   A CD2  1 
ATOM   3110 C  CE1  . HIS   A 1 196 ? 52.841 -30.239 39.729 1.00 93.59  ?  888  HIS   A CE1  1 
ATOM   3111 N  NE2  . HIS   A 1 196 ? 53.872 -30.137 38.924 1.00 95.78  ?  888  HIS   A NE2  1 
ATOM   3112 H  H    . HIS   A 1 196 ? 52.156 -25.999 37.633 1.00 73.94  ?  888  HIS   A H    1 
ATOM   3113 H  HA   . HIS   A 1 196 ? 51.069 -26.423 40.412 1.00 68.75  ?  888  HIS   A HA   1 
ATOM   3114 H  HB2  . HIS   A 1 196 ? 53.961 -26.118 39.643 1.00 74.11  ?  888  HIS   A HB2  1 
ATOM   3115 H  HB3  . HIS   A 1 196 ? 53.316 -26.542 41.186 1.00 74.11  ?  888  HIS   A HB3  1 
ATOM   3116 H  HD1  . HIS   A 1 196 ? 51.674 -28.965 40.892 1.00 82.34  ?  888  HIS   A HD1  1 
ATOM   3117 H  HD2  . HIS   A 1 196 ? 55.001 -28.378 38.338 1.00 95.63  ?  888  HIS   A HD2  1 
ATOM   3118 H  HE1  . HIS   A 1 196 ? 52.357 -31.182 39.948 1.00 95.59  ?  888  HIS   A HE1  1 
ATOM   3119 N  N    . ARG   A 1 197 ? 51.810 -23.659 39.072 1.00 68.99  ?  889  ARG   A N    1 
ATOM   3120 C  CA   . ARG   A 1 197 ? 51.896 -22.215 39.292 1.00 69.24  ?  889  ARG   A CA   1 
ATOM   3121 C  C    . ARG   A 1 197 ? 53.263 -21.748 39.767 1.00 65.79  ?  889  ARG   A C    1 
ATOM   3122 O  O    . ARG   A 1 197 ? 53.404 -20.673 40.351 1.00 67.85  ?  889  ARG   A O    1 
ATOM   3123 C  CB   . ARG   A 1 197 ? 50.737 -21.633 40.092 1.00 68.40  ?  889  ARG   A CB   1 
ATOM   3124 C  CG   . ARG   A 1 197 ? 49.383 -22.051 39.537 1.00 75.47  ?  889  ARG   A CG   1 
ATOM   3125 C  CD   . ARG   A 1 197 ? 48.205 -21.411 40.243 1.00 90.33  ?  889  ARG   A CD   1 
ATOM   3126 N  NE   . ARG   A 1 197 ? 48.170 -21.766 41.670 1.00 100.91 ?  889  ARG   A NE   1 
ATOM   3127 C  CZ   . ARG   A 1 197 ? 47.157 -21.448 42.495 1.00 107.26 ?  889  ARG   A CZ   1 
ATOM   3128 N  NH1  . ARG   A 1 197 ? 46.086 -20.789 42.034 1.00 105.42 ?  889  ARG   A NH1  1 
ATOM   3129 N  NH2  . ARG   A 1 197 ? 47.223 -21.789 43.785 1.00 111.75 1  889  ARG   A NH2  1 
ATOM   3130 H  H    . ARG   A 1 197 ? 51.755 -24.001 38.123 1.00 70.99  ?  889  ARG   A H    1 
ATOM   3131 H  HA   . ARG   A 1 197 ? 51.820 -21.775 38.298 1.00 71.24  ?  889  ARG   A HA   1 
ATOM   3132 H  HB2  . ARG   A 1 197 ? 50.819 -21.932 41.135 1.00 70.40  ?  889  ARG   A HB2  1 
ATOM   3133 H  HB3  . ARG   A 1 197 ? 50.808 -20.544 40.090 1.00 70.40  ?  889  ARG   A HB3  1 
ATOM   3134 H  HG2  . ARG   A 1 197 ? 49.359 -21.773 38.487 1.00 77.47  ?  889  ARG   A HG2  1 
ATOM   3135 H  HG3  . ARG   A 1 197 ? 49.267 -23.135 39.568 1.00 77.47  ?  889  ARG   A HG3  1 
ATOM   3136 H  HD2  . ARG   A 1 197 ? 48.259 -20.330 40.140 1.00 92.33  ?  889  ARG   A HD2  1 
ATOM   3137 H  HD3  . ARG   A 1 197 ? 47.277 -21.735 39.774 1.00 92.33  ?  889  ARG   A HD3  1 
ATOM   3138 H  HE   . ARG   A 1 197 ? 48.973 -22.257 42.045 1.00 102.91 ?  889  ARG   A HE   1 
ATOM   3139 H  HH11 . ARG   A 1 197 ? 46.032 -20.529 41.062 1.00 107.42 ?  889  ARG   A HH11 1 
ATOM   3140 H  HH12 . ARG   A 1 197 ? 45.331 -20.548 42.659 1.00 107.42 ?  889  ARG   A HH12 1 
ATOM   3141 H  HH21 . ARG   A 1 197 ? 48.042 -22.265 44.141 1.00 113.75 ?  889  ARG   A HH21 1 
ATOM   3142 H  HH22 . ARG   A 1 197 ? 46.471 -21.549 44.413 1.00 113.75 ?  889  ARG   A HH22 1 
ATOM   3143 N  N    . ILE   A 1 198 ? 54.265 -22.577 39.504 1.00 64.09  ?  890  ILE   A N    1 
ATOM   3144 C  CA   . ILE   A 1 198 ? 55.646 -22.225 39.758 1.00 64.09  ?  890  ILE   A CA   1 
ATOM   3145 C  C    . ILE   A 1 198 ? 56.088 -21.311 38.621 1.00 65.29  ?  890  ILE   A C    1 
ATOM   3146 O  O    . ILE   A 1 198 ? 55.793 -21.566 37.451 1.00 67.54  ?  890  ILE   A O    1 
ATOM   3147 C  CB   . ILE   A 1 198 ? 56.492 -23.512 39.807 1.00 68.97  ?  890  ILE   A CB   1 
ATOM   3148 C  CG1  . ILE   A 1 198 ? 56.082 -24.405 40.984 1.00 73.02  ?  890  ILE   A CG1  1 
ATOM   3149 C  CG2  . ILE   A 1 198 ? 58.002 -23.262 39.843 1.00 63.01  ?  890  ILE   A CG2  1 
ATOM   3150 C  CD1  . ILE   A 1 198 ? 56.614 -25.831 40.902 1.00 73.56  ?  890  ILE   A CD1  1 
ATOM   3151 H  H    . ILE   A 1 198 ? 54.075 -23.422 38.985 1.00 66.09  ?  890  ILE   A H    1 
ATOM   3152 H  HA   . ILE   A 1 198 ? 55.735 -21.704 40.712 1.00 66.09  ?  890  ILE   A HA   1 
ATOM   3153 H  HB   . ILE   A 1 198 ? 56.288 -24.064 38.888 1.00 70.97  ?  890  ILE   A HB   1 
ATOM   3154 H  HG12 . ILE   A 1 198 ? 56.403 -23.949 41.921 1.00 75.02  ?  890  ILE   A HG12 1 
ATOM   3155 H  HG13 . ILE   A 1 198 ? 54.996 -24.466 41.059 1.00 75.02  ?  890  ILE   A HG13 1 
ATOM   3156 H  HG21 . ILE   A 1 198 ? 58.565 -24.195 39.831 1.00 65.01  ?  890  ILE   A HG21 1 
ATOM   3157 H  HG22 . ILE   A 1 198 ? 58.355 -22.708 38.973 1.00 65.01  ?  890  ILE   A HG22 1 
ATOM   3158 H  HG23 . ILE   A 1 198 ? 58.297 -22.710 40.735 1.00 65.01  ?  890  ILE   A HG23 1 
ATOM   3159 H  HD11 . ILE   A 1 198 ? 56.205 -26.448 41.700 1.00 75.56  ?  890  ILE   A HD11 1 
ATOM   3160 H  HD12 . ILE   A 1 198 ? 56.343 -26.307 39.960 1.00 75.56  ?  890  ILE   A HD12 1 
ATOM   3161 H  HD13 . ILE   A 1 198 ? 57.698 -25.874 40.998 1.00 75.56  ?  890  ILE   A HD13 1 
ATOM   3162 N  N    . TYR   A 1 199 ? 56.796 -20.254 38.979 1.00 61.28  ?  891  TYR   A N    1 
ATOM   3163 C  CA   . TYR   A 1 199 ? 57.309 -19.309 38.005 1.00 51.96  ?  891  TYR   A CA   1 
ATOM   3164 C  C    . TYR   A 1 199 ? 58.734 -18.974 38.378 1.00 49.31  ?  891  TYR   A C    1 
ATOM   3165 O  O    . TYR   A 1 199 ? 59.077 -18.853 39.552 1.00 59.53  ?  891  TYR   A O    1 
ATOM   3166 C  CB   . TYR   A 1 199 ? 56.438 -18.079 37.879 1.00 46.25  ?  891  TYR   A CB   1 
ATOM   3167 C  CG   . TYR   A 1 199 ? 55.090 -18.252 37.194 1.00 42.51  ?  891  TYR   A CG   1 
ATOM   3168 C  CD1  . TYR   A 1 199 ? 54.986 -18.108 35.796 1.00 21.96  ?  891  TYR   A CD1  1 
ATOM   3169 C  CD2  . TYR   A 1 199 ? 53.938 -18.532 37.957 1.00 38.30  ?  891  TYR   A CD2  1 
ATOM   3170 C  CE1  . TYR   A 1 199 ? 53.730 -18.217 35.165 1.00 37.53  ?  891  TYR   A CE1  1 
ATOM   3171 C  CE2  . TYR   A 1 199 ? 52.683 -18.653 37.325 1.00 28.97  ?  891  TYR   A CE2  1 
ATOM   3172 C  CZ   . TYR   A 1 199 ? 52.576 -18.484 35.932 1.00 41.45  ?  891  TYR   A CZ   1 
ATOM   3173 O  OH   . TYR   A 1 199 ? 51.356 -18.577 35.325 1.00 55.57  ?  891  TYR   A OH   1 
ATOM   3174 H  H    . TYR   A 1 199 ? 57.044 -20.104 39.947 1.00 63.28  ?  891  TYR   A H    1 
ATOM   3175 H  HA   . TYR   A 1 199 ? 57.350 -19.778 37.022 1.00 53.96  ?  891  TYR   A HA   1 
ATOM   3176 H  HB2  . TYR   A 1 199 ? 56.277 -17.646 38.866 1.00 48.25  ?  891  TYR   A HB2  1 
ATOM   3177 H  HB3  . TYR   A 1 199 ? 56.979 -17.315 37.320 1.00 48.25  ?  891  TYR   A HB3  1 
ATOM   3178 H  HD1  . TYR   A 1 199 ? 55.866 -17.899 35.209 1.00 23.96  ?  891  TYR   A HD1  1 
ATOM   3179 H  HD2  . TYR   A 1 199 ? 54.015 -18.644 39.030 1.00 40.30  ?  891  TYR   A HD2  1 
ATOM   3180 H  HE1  . TYR   A 1 199 ? 53.655 -18.093 34.094 1.00 39.53  ?  891  TYR   A HE1  1 
ATOM   3181 H  HE2  . TYR   A 1 199 ? 51.801 -18.862 37.914 1.00 30.97  ?  891  TYR   A HE2  1 
ATOM   3182 H  HH   . TYR   A 1 199 ? 51.406 -18.517 34.380 1.00 57.57  ?  891  TYR   A HH   1 
ATOM   3183 N  N    . THR   A 1 200 ? 59.598 -18.888 37.387 1.00 47.93  ?  892  THR   A N    1 
ATOM   3184 C  CA   . THR   A 1 200 ? 61.032 -18.737 37.600 1.00 37.40  ?  892  THR   A CA   1 
ATOM   3185 C  C    . THR   A 1 200 ? 61.576 -17.999 36.378 1.00 38.47  ?  892  THR   A C    1 
ATOM   3186 O  O    . THR   A 1 200 ? 60.906 -17.899 35.346 1.00 34.20  ?  892  THR   A O    1 
ATOM   3187 C  CB   . THR   A 1 200 ? 61.661 -20.118 37.916 1.00 49.95  ?  892  THR   A CB   1 
ATOM   3188 O  OG1  . THR   A 1 200 ? 61.299 -20.544 39.224 1.00 53.07  ?  892  THR   A OG1  1 
ATOM   3189 C  CG2  . THR   A 1 200 ? 63.180 -20.204 37.945 1.00 54.50  ?  892  THR   A CG2  1 
ATOM   3190 H  H    . THR   A 1 200 ? 59.278 -18.988 36.416 1.00 49.93  ?  892  THR   A H    1 
ATOM   3191 H  HA   . THR   A 1 200 ? 61.210 -18.062 38.441 1.00 39.40  ?  892  THR   A HA   1 
ATOM   3192 H  HB   . THR   A 1 200 ? 61.285 -20.852 37.200 1.00 51.95  ?  892  THR   A HB   1 
ATOM   3193 H  HG1  . THR   A 1 200 ? 60.468 -20.125 39.449 1.00 55.07  ?  892  THR   A HG1  1 
ATOM   3194 H  HG21 . THR   A 1 200 ? 63.504 -21.196 38.264 1.00 56.50  ?  892  THR   A HG21 1 
ATOM   3195 H  HG22 . THR   A 1 200 ? 63.633 -20.042 36.977 1.00 56.50  ?  892  THR   A HG22 1 
ATOM   3196 H  HG23 . THR   A 1 200 ? 63.608 -19.483 38.644 1.00 56.50  ?  892  THR   A HG23 1 
ATOM   3197 N  N    . HIS   A 1 201 ? 62.817 -17.528 36.435 1.00 29.19  ?  893  HIS   A N    1 
ATOM   3198 C  CA   . HIS   A 1 201 ? 63.499 -17.076 35.212 1.00 39.96  ?  893  HIS   A CA   1 
ATOM   3199 C  C    . HIS   A 1 201 ? 63.538 -18.142 34.121 1.00 42.20  ?  893  HIS   A C    1 
ATOM   3200 O  O    . HIS   A 1 201 ? 63.279 -17.894 32.947 1.00 44.75  ?  893  HIS   A O    1 
ATOM   3201 C  CB   . HIS   A 1 201 ? 64.904 -16.576 35.516 1.00 40.13  ?  893  HIS   A CB   1 
ATOM   3202 C  CG   . HIS   A 1 201 ? 64.957 -15.551 36.621 1.00 47.36  ?  893  HIS   A CG   1 
ATOM   3203 N  ND1  . HIS   A 1 201 ? 64.331 -14.318 36.534 1.00 53.86  ?  893  HIS   A ND1  1 
ATOM   3204 C  CD2  . HIS   A 1 201 ? 65.566 -15.557 37.874 1.00 48.16  ?  893  HIS   A CD2  1 
ATOM   3205 C  CE1  . HIS   A 1 201 ? 64.563 -13.676 37.659 1.00 44.53  ?  893  HIS   A CE1  1 
ATOM   3206 N  NE2  . HIS   A 1 201 ? 65.294 -14.341 38.516 1.00 50.42  ?  893  HIS   A NE2  1 
ATOM   3207 H  H    . HIS   A 1 201 ? 63.323 -17.500 37.307 1.00 31.19  ?  893  HIS   A H    1 
ATOM   3208 H  HA   . HIS   A 1 201 ? 62.927 -16.234 34.815 1.00 41.96  ?  893  HIS   A HA   1 
ATOM   3209 H  HB2  . HIS   A 1 201 ? 65.560 -17.404 35.790 1.00 42.13  ?  893  HIS   A HB2  1 
ATOM   3210 H  HB3  . HIS   A 1 201 ? 65.340 -16.130 34.620 1.00 42.13  ?  893  HIS   A HB3  1 
ATOM   3211 H  HD1  . HIS   A 1 201 ? 63.804 -13.958 35.724 1.00 55.86  ?  893  HIS   A HD1  1 
ATOM   3212 H  HD2  . HIS   A 1 201 ? 66.162 -16.325 38.347 1.00 50.16  ?  893  HIS   A HD2  1 
ATOM   3213 H  HE1  . HIS   A 1 201 ? 64.192 -12.682 37.854 1.00 46.53  ?  893  HIS   A HE1  1 
ATOM   3214 N  N    . GLN   A 1 202 ? 63.718 -19.381 34.560 1.00 43.94  ?  894  GLN   A N    1 
ATOM   3215 C  CA   . GLN   A 1 202 ? 63.706 -20.526 33.665 1.00 37.27  ?  894  GLN   A CA   1 
ATOM   3216 C  C    . GLN   A 1 202 ? 62.341 -20.878 33.116 1.00 35.89  ?  894  GLN   A C    1 
ATOM   3217 O  O    . GLN   A 1 202 ? 62.273 -21.545 32.081 1.00 41.54  ?  894  GLN   A O    1 
ATOM   3218 C  CB   . GLN   A 1 202 ? 64.286 -21.747 34.373 1.00 30.23  ?  894  GLN   A CB   1 
ATOM   3219 C  CG   . GLN   A 1 202 ? 65.740 -21.569 34.824 1.00 30.05  ?  894  GLN   A CG   1 
ATOM   3220 C  CD   . GLN   A 1 202 ? 66.656 -21.179 33.684 1.00 44.66  ?  894  GLN   A CD   1 
ATOM   3221 O  OE1  . GLN   A 1 202 ? 67.149 -20.057 33.608 1.00 41.62  ?  894  GLN   A OE1  1 
ATOM   3222 N  NE2  . GLN   A 1 202 ? 66.889 -22.102 32.781 1.00 39.09  ?  894  GLN   A NE2  1 
ATOM   3223 H  H    . GLN   A 1 202 ? 63.919 -19.519 35.536 1.00 45.94  ?  894  GLN   A H    1 
ATOM   3224 H  HA   . GLN   A 1 202 ? 64.314 -20.285 32.791 1.00 39.27  ?  894  GLN   A HA   1 
ATOM   3225 H  HB2  . GLN   A 1 202 ? 63.673 -22.002 35.239 1.00 32.23  ?  894  GLN   A HB2  1 
ATOM   3226 H  HB3  . GLN   A 1 202 ? 64.232 -22.613 33.711 1.00 32.23  ?  894  GLN   A HB3  1 
ATOM   3227 H  HG2  . GLN   A 1 202 ? 65.811 -20.807 35.601 1.00 32.05  ?  894  GLN   A HG2  1 
ATOM   3228 H  HG3  . GLN   A 1 202 ? 66.106 -22.492 35.276 1.00 32.05  ?  894  GLN   A HG3  1 
ATOM   3229 H  HE21 . GLN   A 1 202 ? 66.484 -23.025 32.884 1.00 41.09  ?  894  GLN   A HE21 1 
ATOM   3230 H  HE22 . GLN   A 1 202 ? 67.480 -21.890 31.981 1.00 41.09  ?  894  GLN   A HE22 1 
ATOM   3231 N  N    . SER   A 1 203 ? 61.264 -20.419 33.753 1.00 32.72  ?  895  SER   A N    1 
ATOM   3232 C  CA   . SER   A 1 203 ? 59.961 -20.552 33.106 1.00 34.89  ?  895  SER   A CA   1 
ATOM   3233 C  C    . SER   A 1 203 ? 59.757 -19.478 32.043 1.00 30.07  ?  895  SER   A C    1 
ATOM   3234 O  O    . SER   A 1 203 ? 59.047 -19.715 31.068 1.00 36.05  ?  895  SER   A O    1 
ATOM   3235 C  CB   . SER   A 1 203 ? 58.807 -20.593 34.117 1.00 35.98  ?  895  SER   A CB   1 
ATOM   3236 O  OG   . SER   A 1 203 ? 58.614 -19.417 34.883 1.00 52.71  ?  895  SER   A OG   1 
ATOM   3237 H  H    . SER   A 1 203 ? 61.337 -19.759 34.516 1.00 34.72  ?  895  SER   A H    1 
ATOM   3238 H  HA   . SER   A 1 203 ? 59.907 -21.511 32.586 1.00 36.89  ?  895  SER   A HA   1 
ATOM   3239 H  HB2  . SER   A 1 203 ? 57.869 -20.790 33.594 1.00 37.98  ?  895  SER   A HB2  1 
ATOM   3240 H  HB3  . SER   A 1 203 ? 58.946 -21.431 34.801 1.00 37.98  ?  895  SER   A HB3  1 
ATOM   3241 H  HG   . SER   A 1 203 ? 58.213 -18.746 34.316 1.00 54.71  ?  895  SER   A HG   1 
ATOM   3242 N  N    . ASP   A 1 204 ? 60.438 -18.335 32.186 1.00 33.40  ?  896  ASP   A N    1 
ATOM   3243 C  CA   . ASP   A 1 204 ? 60.462 -17.339 31.115 1.00 44.32  ?  896  ASP   A CA   1 
ATOM   3244 C  C    . ASP   A 1 204 ? 61.301 -17.794 29.929 1.00 43.04  ?  896  ASP   A C    1 
ATOM   3245 O  O    . ASP   A 1 204 ? 60.975 -17.459 28.792 1.00 39.04  ?  896  ASP   A O    1 
ATOM   3246 C  CB   . ASP   A 1 204 ? 61.006 -15.970 31.556 1.00 40.03  ?  896  ASP   A CB   1 
ATOM   3247 C  CG   . ASP   A 1 204 ? 60.132 -15.179 32.507 1.00 47.02  ?  896  ASP   A CG   1 
ATOM   3248 O  OD1  . ASP   A 1 204 ? 58.889 -15.291 32.429 1.00 29.21  ?  896  ASP   A OD1  1 
ATOM   3249 O  OD2  . ASP   A 1 204 ? 60.679 -14.417 33.330 1.00 27.50  -1 896  ASP   A OD2  1 
ATOM   3250 H  H    . ASP   A 1 204 ? 61.008 -18.183 33.009 1.00 35.40  ?  896  ASP   A H    1 
ATOM   3251 H  HA   . ASP   A 1 204 ? 59.445 -17.203 30.738 1.00 46.32  ?  896  ASP   A HA   1 
ATOM   3252 H  HB2  . ASP   A 1 204 ? 62.007 -16.048 31.971 1.00 42.03  ?  896  ASP   A HB2  1 
ATOM   3253 H  HB3  . ASP   A 1 204 ? 61.098 -15.344 30.670 1.00 42.03  ?  896  ASP   A HB3  1 
ATOM   3254 N  N    . VAL   A 1 205 ? 62.356 -18.571 30.175 1.00 30.30  ?  897  VAL   A N    1 
ATOM   3255 C  CA   . VAL   A 1 205 ? 63.071 -19.247 29.092 1.00 38.52  ?  897  VAL   A CA   1 
ATOM   3256 C  C    . VAL   A 1 205 ? 62.161 -20.091 28.197 1.00 38.09  ?  897  VAL   A C    1 
ATOM   3257 O  O    . VAL   A 1 205 ? 62.249 -19.998 26.971 1.00 32.32  ?  897  VAL   A O    1 
ATOM   3258 C  CB   . VAL   A 1 205 ? 64.302 -20.010 29.594 1.00 36.55  ?  897  VAL   A CB   1 
ATOM   3259 C  CG1  . VAL   A 1 205 ? 64.990 -20.832 28.513 1.00 35.77  ?  897  VAL   A CG1  1 
ATOM   3260 C  CG2  . VAL   A 1 205 ? 65.322 -19.071 30.232 1.00 34.81  ?  897  VAL   A CG2  1 
ATOM   3261 H  H    . VAL   A 1 205 ? 62.661 -18.685 31.133 1.00 32.30  ?  897  VAL   A H    1 
ATOM   3262 H  HA   . VAL   A 1 205 ? 63.454 -18.452 28.450 1.00 40.52  ?  897  VAL   A HA   1 
ATOM   3263 H  HB   . VAL   A 1 205 ? 63.979 -20.713 30.360 1.00 38.55  ?  897  VAL   A HB   1 
ATOM   3264 H  HG11 . VAL   A 1 205 ? 65.914 -21.279 28.872 1.00 37.77  ?  897  VAL   A HG11 1 
ATOM   3265 H  HG12 . VAL   A 1 205 ? 64.371 -21.657 28.166 1.00 37.77  ?  897  VAL   A HG12 1 
ATOM   3266 H  HG13 . VAL   A 1 205 ? 65.238 -20.216 27.650 1.00 37.77  ?  897  VAL   A HG13 1 
ATOM   3267 H  HG21 . VAL   A 1 205 ? 66.151 -19.621 30.676 1.00 36.81  ?  897  VAL   A HG21 1 
ATOM   3268 H  HG22 . VAL   A 1 205 ? 65.745 -18.380 29.502 1.00 36.81  ?  897  VAL   A HG22 1 
ATOM   3269 H  HG23 . VAL   A 1 205 ? 64.892 -18.471 31.030 1.00 36.81  ?  897  VAL   A HG23 1 
ATOM   3270 N  N    . TRP   A 1 206 ? 61.231 -20.835 28.800 1.00 30.47  ?  898  TRP   A N    1 
ATOM   3271 C  CA   . TRP   A 1 206 ? 60.227 -21.559 28.012 1.00 29.85  ?  898  TRP   A CA   1 
ATOM   3272 C  C    . TRP   A 1 206 ? 59.442 -20.647 27.095 1.00 35.63  ?  898  TRP   A C    1 
ATOM   3273 O  O    . TRP   A 1 206 ? 59.307 -20.894 25.893 1.00 49.33  ?  898  TRP   A O    1 
ATOM   3274 C  CB   . TRP   A 1 206 ? 59.282 -22.347 28.911 1.00 28.03  ?  898  TRP   A CB   1 
ATOM   3275 C  CG   . TRP   A 1 206 ? 58.325 -23.316 28.266 1.00 23.21  ?  898  TRP   A CG   1 
ATOM   3276 C  CD1  . TRP   A 1 206 ? 57.338 -22.991 27.400 1.00 27.06  ?  898  TRP   A CD1  1 
ATOM   3277 C  CD2  . TRP   A 1 206 ? 58.236 -24.765 28.444 1.00 24.31  ?  898  TRP   A CD2  1 
ATOM   3278 N  NE1  . TRP   A 1 206 ? 56.663 -24.127 27.020 1.00 33.61  ?  898  TRP   A NE1  1 
ATOM   3279 C  CE2  . TRP   A 1 206 ? 57.161 -25.252 27.641 1.00 29.43  ?  898  TRP   A CE2  1 
ATOM   3280 C  CE3  . TRP   A 1 206 ? 58.944 -25.725 29.214 1.00 37.87  ?  898  TRP   A CE3  1 
ATOM   3281 C  CZ2  . TRP   A 1 206 ? 56.804 -26.600 27.601 1.00 26.81  ?  898  TRP   A CZ2  1 
ATOM   3282 C  CZ3  . TRP   A 1 206 ? 58.583 -27.092 29.180 1.00 38.05  ?  898  TRP   A CZ3  1 
ATOM   3283 C  CH2  . TRP   A 1 206 ? 57.514 -27.526 28.375 1.00 33.43  ?  898  TRP   A CH2  1 
ATOM   3284 H  H    . TRP   A 1 206 ? 61.162 -20.819 29.807 1.00 32.47  ?  898  TRP   A H    1 
ATOM   3285 H  HA   . TRP   A 1 206 ? 60.753 -22.263 27.371 1.00 31.85  ?  898  TRP   A HA   1 
ATOM   3286 H  HB2  . TRP   A 1 206 ? 59.873 -22.918 29.627 1.00 30.03  ?  898  TRP   A HB2  1 
ATOM   3287 H  HB3  . TRP   A 1 206 ? 58.674 -21.666 29.505 1.00 30.03  ?  898  TRP   A HB3  1 
ATOM   3288 H  HD1  . TRP   A 1 206 ? 57.122 -21.987 27.064 1.00 29.06  ?  898  TRP   A HD1  1 
ATOM   3289 H  HE1  . TRP   A 1 206 ? 55.875 -24.106 26.356 1.00 35.61  ?  898  TRP   A HE1  1 
ATOM   3290 H  HE3  . TRP   A 1 206 ? 59.765 -25.406 29.835 1.00 39.87  ?  898  TRP   A HE3  1 
ATOM   3291 H  HZ2  . TRP   A 1 206 ? 55.985 -26.920 26.981 1.00 28.81  ?  898  TRP   A HZ2  1 
ATOM   3292 H  HZ3  . TRP   A 1 206 ? 59.133 -27.808 29.773 1.00 40.05  ?  898  TRP   A HZ3  1 
ATOM   3293 H  HH2  . TRP   A 1 206 ? 57.243 -28.572 28.350 1.00 35.43  ?  898  TRP   A HH2  1 
ATOM   3294 N  N    . SER   A 1 207 ? 58.986 -19.548 27.676 1.00 35.33  ?  899  SER   A N    1 
ATOM   3295 C  CA   . SER   A 1 207 ? 58.195 -18.576 26.937 1.00 26.62  ?  899  SER   A CA   1 
ATOM   3296 C  C    . SER   A 1 207 ? 59.008 -17.878 25.855 1.00 23.90  ?  899  SER   A C    1 
ATOM   3297 O  O    . SER   A 1 207 ? 58.486 -17.572 24.782 1.00 25.63  ?  899  SER   A O    1 
ATOM   3298 C  CB   . SER   A 1 207 ? 57.644 -17.523 27.896 1.00 30.30  ?  899  SER   A CB   1 
ATOM   3299 O  OG   . SER   A 1 207 ? 57.069 -18.087 29.069 1.00 36.76  ?  899  SER   A OG   1 
ATOM   3300 H  H    . SER   A 1 207 ? 59.093 -19.407 28.673 1.00 37.33  ?  899  SER   A H    1 
ATOM   3301 H  HA   . SER   A 1 207 ? 57.363 -19.094 26.455 1.00 28.62  ?  899  SER   A HA   1 
ATOM   3302 H  HB2  . SER   A 1 207 ? 58.430 -16.834 28.205 1.00 32.30  ?  899  SER   A HB2  1 
ATOM   3303 H  HB3  . SER   A 1 207 ? 56.883 -16.934 27.388 1.00 32.30  ?  899  SER   A HB3  1 
ATOM   3304 H  HG   . SER   A 1 207 ? 56.433 -18.745 28.772 1.00 38.76  ?  899  SER   A HG   1 
ATOM   3305 N  N    . TYR   A 1 208 ? 60.299 -17.677 26.127 1.00 23.88  ?  900  TYR   A N    1 
ATOM   3306 C  CA   . TYR   A 1 208 ? 61.265 -17.221 25.136 1.00 33.87  ?  900  TYR   A CA   1 
ATOM   3307 C  C    . TYR   A 1 208 ? 61.350 -18.171 23.953 1.00 34.70  ?  900  TYR   A C    1 
ATOM   3308 O  O    . TYR   A 1 208 ? 61.269 -17.737 22.805 1.00 26.31  ?  900  TYR   A O    1 
ATOM   3309 C  CB   . TYR   A 1 208 ? 62.638 -16.982 25.765 1.00 27.86  ?  900  TYR   A CB   1 
ATOM   3310 C  CG   . TYR   A 1 208 ? 63.748 -16.571 24.810 1.00 37.49  ?  900  TYR   A CG   1 
ATOM   3311 C  CD1  . TYR   A 1 208 ? 64.001 -15.208 24.567 1.00 28.02  ?  900  TYR   A CD1  1 
ATOM   3312 C  CD2  . TYR   A 1 208 ? 64.527 -17.556 24.165 1.00 42.24  ?  900  TYR   A CD2  1 
ATOM   3313 C  CE1  . TYR   A 1 208 ? 65.029 -14.829 23.681 1.00 35.18  ?  900  TYR   A CE1  1 
ATOM   3314 C  CE2  . TYR   A 1 208 ? 65.551 -17.176 23.278 1.00 27.80  ?  900  TYR   A CE2  1 
ATOM   3315 C  CZ   . TYR   A 1 208 ? 65.802 -15.814 23.036 1.00 34.22  ?  900  TYR   A CZ   1 
ATOM   3316 O  OH   . TYR   A 1 208 ? 66.796 -15.451 22.180 1.00 29.30  ?  900  TYR   A OH   1 
ATOM   3317 H  H    . TYR   A 1 208 ? 60.633 -17.904 27.061 1.00 25.88  ?  900  TYR   A H    1 
ATOM   3318 H  HA   . TYR   A 1 208 ? 60.910 -16.262 24.752 1.00 35.87  ?  900  TYR   A HA   1 
ATOM   3319 H  HB2  . TYR   A 1 208 ? 62.539 -16.225 26.541 1.00 29.86  ?  900  TYR   A HB2  1 
ATOM   3320 H  HB3  . TYR   A 1 208 ? 62.995 -17.867 26.276 1.00 29.86  ?  900  TYR   A HB3  1 
ATOM   3321 H  HD1  . TYR   A 1 208 ? 63.408 -14.454 25.059 1.00 30.02  ?  900  TYR   A HD1  1 
ATOM   3322 H  HD2  . TYR   A 1 208 ? 64.337 -18.605 24.349 1.00 44.24  ?  900  TYR   A HD2  1 
ATOM   3323 H  HE1  . TYR   A 1 208 ? 65.222 -13.785 23.495 1.00 37.18  ?  900  TYR   A HE1  1 
ATOM   3324 H  HE2  . TYR   A 1 208 ? 66.145 -17.930 22.784 1.00 29.80  ?  900  TYR   A HE2  1 
ATOM   3325 H  HH   . TYR   A 1 208 ? 66.901 -14.504 22.095 1.00 31.30  ?  900  TYR   A HH   1 
ATOM   3326 N  N    . GLY   A 1 209 ? 61.413 -19.466 24.245 1.00 26.78  ?  901  GLY   A N    1 
ATOM   3327 C  CA   . GLY   A 1 209 ? 61.383 -20.483 23.202 1.00 24.64  ?  901  GLY   A CA   1 
ATOM   3328 C  C    . GLY   A 1 209 ? 60.165 -20.430 22.313 1.00 25.65  ?  901  GLY   A C    1 
ATOM   3329 O  O    . GLY   A 1 209 ? 60.281 -20.458 21.083 1.00 38.90  ?  901  GLY   A O    1 
ATOM   3330 H  H    . GLY   A 1 209 ? 61.480 -19.754 25.219 1.00 28.78  ?  901  GLY   A H    1 
ATOM   3331 H  HA2  . GLY   A 1 209 ? 62.282 -20.395 22.589 1.00 26.64  ?  901  GLY   A HA2  1 
ATOM   3332 H  HA3  . GLY   A 1 209 ? 61.427 -21.465 23.673 1.00 26.64  ?  901  GLY   A HA3  1 
ATOM   3333 N  N    . VAL   A 1 210 ? 58.999 -20.264 22.938 1.00 28.35  ?  902  VAL   A N    1 
ATOM   3334 C  CA   . VAL   A 1 210 ? 57.767 -20.082 22.162 1.00 23.43  ?  902  VAL   A CA   1 
ATOM   3335 C  C    . VAL   A 1 210 ? 57.791 -18.790 21.361 1.00 26.68  ?  902  VAL   A C    1 
ATOM   3336 O  O    . VAL   A 1 210 ? 57.356 -18.758 20.208 1.00 32.68  ?  902  VAL   A O    1 
ATOM   3337 C  CB   . VAL   A 1 210 ? 56.512 -20.167 23.053 1.00 33.20  ?  902  VAL   A CB   1 
ATOM   3338 C  CG1  . VAL   A 1 210 ? 55.205 -20.054 22.270 1.00 24.36  ?  902  VAL   A CG1  1 
ATOM   3339 C  CG2  . VAL   A 1 210 ? 56.484 -21.453 23.874 1.00 21.48  ?  902  VAL   A CG2  1 
ATOM   3340 H  H    . VAL   A 1 210 ? 58.977 -20.194 23.950 1.00 30.35  ?  902  VAL   A H    1 
ATOM   3341 H  HA   . VAL   A 1 210 ? 57.704 -20.899 21.440 1.00 25.43  ?  902  VAL   A HA   1 
ATOM   3342 H  HB   . VAL   A 1 210 ? 56.536 -19.334 23.758 1.00 35.20  ?  902  VAL   A HB   1 
ATOM   3343 H  HG11 . VAL   A 1 210 ? 54.341 -20.134 22.930 1.00 26.36  ?  902  VAL   A HG11 1 
ATOM   3344 H  HG12 . VAL   A 1 210 ? 55.105 -19.098 21.756 1.00 26.36  ?  902  VAL   A HG12 1 
ATOM   3345 H  HG13 . VAL   A 1 210 ? 55.120 -20.841 21.521 1.00 26.36  ?  902  VAL   A HG13 1 
ATOM   3346 H  HG21 . VAL   A 1 210 ? 55.584 -21.520 24.481 1.00 23.48  ?  902  VAL   A HG21 1 
ATOM   3347 H  HG22 . VAL   A 1 210 ? 56.506 -22.335 23.233 1.00 23.48  ?  902  VAL   A HG22 1 
ATOM   3348 H  HG23 . VAL   A 1 210 ? 57.321 -21.531 24.562 1.00 23.48  ?  902  VAL   A HG23 1 
ATOM   3349 N  N    . THR   A 1 211 ? 58.356 -17.743 21.958 1.00 24.54  ?  903  THR   A N    1 
ATOM   3350 C  CA   . THR   A 1 211 ? 58.459 -16.442 21.294 1.00 24.66  ?  903  THR   A CA   1 
ATOM   3351 C  C    . THR   A 1 211 ? 59.334 -16.528 20.052 1.00 32.67  ?  903  THR   A C    1 
ATOM   3352 O  O    . THR   A 1 211 ? 58.936 -16.044 18.996 1.00 32.00  ?  903  THR   A O    1 
ATOM   3353 C  CB   . THR   A 1 211 ? 58.978 -15.345 22.244 1.00 37.44  ?  903  THR   A CB   1 
ATOM   3354 O  OG1  . THR   A 1 211 ? 58.110 -15.219 23.357 1.00 32.04  ?  903  THR   A OG1  1 
ATOM   3355 C  CG2  . THR   A 1 211 ? 59.088 -13.953 21.613 1.00 15.51  ?  903  THR   A CG2  1 
ATOM   3356 H  H    . THR   A 1 211 ? 58.695 -17.838 22.908 1.00 26.54  ?  903  THR   A H    1 
ATOM   3357 H  HA   . THR   A 1 211 ? 57.458 -16.158 20.964 1.00 26.66  ?  903  THR   A HA   1 
ATOM   3358 H  HB   . THR   A 1 211 ? 59.963 -15.612 22.624 1.00 39.44  ?  903  THR   A HB   1 
ATOM   3359 H  HG1  . THR   A 1 211 ? 58.129 -16.035 23.858 1.00 34.04  ?  903  THR   A HG1  1 
ATOM   3360 H  HG21 . THR   A 1 211 ? 59.335 -13.201 22.363 1.00 17.51  ?  903  THR   A HG21 1 
ATOM   3361 H  HG22 . THR   A 1 211 ? 59.867 -13.911 20.851 1.00 17.51  ?  903  THR   A HG22 1 
ATOM   3362 H  HG23 . THR   A 1 211 ? 58.152 -13.660 21.144 1.00 17.51  ?  903  THR   A HG23 1 
ATOM   3363 N  N    . VAL   A 1 212 ? 60.485 -17.197 20.169 1.00 29.80  ?  904  VAL   A N    1 
ATOM   3364 C  CA   . VAL   A 1 212 ? 61.349 -17.469 19.025 1.00 26.65  ?  904  VAL   A CA   1 
ATOM   3365 C  C    . VAL   A 1 212 ? 60.616 -18.243 17.936 1.00 31.80  ?  904  VAL   A C    1 
ATOM   3366 O  O    . VAL   A 1 212 ? 60.630 -17.854 16.766 1.00 28.29  ?  904  VAL   A O    1 
ATOM   3367 C  CB   . VAL   A 1 212 ? 62.646 -18.166 19.468 1.00 28.49  ?  904  VAL   A CB   1 
ATOM   3368 C  CG1  . VAL   A 1 212 ? 63.503 -18.655 18.305 1.00 31.38  ?  904  VAL   A CG1  1 
ATOM   3369 C  CG2  . VAL   A 1 212 ? 63.497 -17.276 20.365 1.00 23.94  ?  904  VAL   A CG2  1 
ATOM   3370 H  H    . VAL   A 1 212 ? 60.752 -17.565 21.080 1.00 31.80  ?  904  VAL   A H    1 
ATOM   3371 H  HA   . VAL   A 1 212 ? 61.623 -16.506 18.587 1.00 28.65  ?  904  VAL   A HA   1 
ATOM   3372 H  HB   . VAL   A 1 212 ? 62.370 -19.047 20.051 1.00 30.49  ?  904  VAL   A HB   1 
ATOM   3373 H  HG11 . VAL   A 1 212 ? 64.412 -19.139 18.663 1.00 33.38  ?  904  VAL   A HG11 1 
ATOM   3374 H  HG12 . VAL   A 1 212 ? 62.979 -19.385 17.695 1.00 33.38  ?  904  VAL   A HG12 1 
ATOM   3375 H  HG13 . VAL   A 1 212 ? 63.800 -17.829 17.660 1.00 33.38  ?  904  VAL   A HG13 1 
ATOM   3376 H  HG21 . VAL   A 1 212 ? 64.372 -17.813 20.731 1.00 25.94  ?  904  VAL   A HG21 1 
ATOM   3377 H  HG22 . VAL   A 1 212 ? 63.856 -16.399 19.828 1.00 25.94  ?  904  VAL   A HG22 1 
ATOM   3378 H  HG23 . VAL   A 1 212 ? 62.961 -16.910 21.237 1.00 25.94  ?  904  VAL   A HG23 1 
ATOM   3379 N  N    . TRP   A 1 213 ? 59.928 -19.302 18.342 1.00 23.58  ?  905  TRP   A N    1 
ATOM   3380 C  CA   . TRP   A 1 213 ? 59.064 -20.036 17.425 1.00 27.97  ?  905  TRP   A CA   1 
ATOM   3381 C  C    . TRP   A 1 213 ? 58.025 -19.179 16.691 1.00 35.47  ?  905  TRP   A C    1 
ATOM   3382 O  O    . TRP   A 1 213 ? 57.827 -19.332 15.482 1.00 36.76  ?  905  TRP   A O    1 
ATOM   3383 C  CB   . TRP   A 1 213 ? 58.443 -21.217 18.146 1.00 29.95  ?  905  TRP   A CB   1 
ATOM   3384 C  CG   . TRP   A 1 213 ? 57.705 -22.168 17.270 1.00 41.61  ?  905  TRP   A CG   1 
ATOM   3385 C  CD1  . TRP   A 1 213 ? 58.210 -23.310 16.763 1.00 40.78  ?  905  TRP   A CD1  1 
ATOM   3386 C  CD2  . TRP   A 1 213 ? 56.335 -22.080 16.775 1.00 45.06  ?  905  TRP   A CD2  1 
ATOM   3387 N  NE1  . TRP   A 1 213 ? 57.260 -23.934 15.991 1.00 49.46  ?  905  TRP   A NE1  1 
ATOM   3388 C  CE2  . TRP   A 1 213 ? 56.077 -23.227 15.960 1.00 38.73  ?  905  TRP   A CE2  1 
ATOM   3389 C  CE3  . TRP   A 1 213 ? 55.272 -21.147 16.925 1.00 33.59  ?  905  TRP   A CE3  1 
ATOM   3390 C  CZ2  . TRP   A 1 213 ? 54.844 -23.444 15.330 1.00 40.78  ?  905  TRP   A CZ2  1 
ATOM   3391 C  CZ3  . TRP   A 1 213 ? 54.027 -21.358 16.286 1.00 51.88  ?  905  TRP   A CZ3  1 
ATOM   3392 C  CH2  . TRP   A 1 213 ? 53.813 -22.505 15.491 1.00 48.91  ?  905  TRP   A CH2  1 
ATOM   3393 H  H    . TRP   A 1 213 ? 59.953 -19.571 19.322 1.00 25.58  ?  905  TRP   A H    1 
ATOM   3394 H  HA   . TRP   A 1 213 ? 59.720 -20.448 16.655 1.00 29.97  ?  905  TRP   A HA   1 
ATOM   3395 H  HB2  . TRP   A 1 213 ? 59.227 -21.779 18.655 1.00 31.95  ?  905  TRP   A HB2  1 
ATOM   3396 H  HB3  . TRP   A 1 213 ? 57.756 -20.888 18.924 1.00 31.95  ?  905  TRP   A HB3  1 
ATOM   3397 H  HD1  . TRP   A 1 213 ? 59.216 -23.664 16.941 1.00 42.78  ?  905  TRP   A HD1  1 
ATOM   3398 H  HE1  . TRP   A 1 213 ? 57.449 -24.818 15.501 1.00 51.46  ?  905  TRP   A HE1  1 
ATOM   3399 H  HE3  . TRP   A 1 213 ? 55.417 -20.265 17.531 1.00 35.59  ?  905  TRP   A HE3  1 
ATOM   3400 H  HZ2  . TRP   A 1 213 ? 54.691 -24.320 14.719 1.00 42.78  ?  905  TRP   A HZ2  1 
ATOM   3401 H  HZ3  . TRP   A 1 213 ? 53.236 -20.636 16.410 1.00 53.88  ?  905  TRP   A HZ3  1 
ATOM   3402 H  HH2  . TRP   A 1 213 ? 52.861 -22.656 15.005 1.00 50.91  ?  905  TRP   A HH2  1 
ATOM   3403 N  N    . GLU   A 1 214 ? 57.415 -18.222 17.392 1.00 36.62  ?  906  GLU   A N    1 
ATOM   3404 C  CA   . GLU   A 1 214 ? 56.541 -17.254 16.729 1.00 32.08  ?  906  GLU   A CA   1 
ATOM   3405 C  C    . GLU   A 1 214 ? 57.264 -16.401 15.697 1.00 35.15  ?  906  GLU   A C    1 
ATOM   3406 O  O    . GLU   A 1 214 ? 56.749 -16.188 14.599 1.00 37.19  ?  906  GLU   A O    1 
ATOM   3407 C  CB   . GLU   A 1 214 ? 55.854 -16.311 17.710 1.00 36.90  ?  906  GLU   A CB   1 
ATOM   3408 C  CG   . GLU   A 1 214 ? 54.853 -16.958 18.661 1.00 39.23  ?  906  GLU   A CG   1 
ATOM   3409 C  CD   . GLU   A 1 214 ? 54.282 -15.895 19.567 1.00 51.46  ?  906  GLU   A CD   1 
ATOM   3410 O  OE1  . GLU   A 1 214 ? 53.231 -15.312 19.225 1.00 45.86  ?  906  GLU   A OE1  1 
ATOM   3411 O  OE2  . GLU   A 1 214 ? 54.880 -15.621 20.628 1.00 43.18  -1 906  GLU   A OE2  1 
ATOM   3412 H  H    . GLU   A 1 214 ? 57.566 -18.160 18.397 1.00 38.62  ?  906  GLU   A H    1 
ATOM   3413 H  HA   . GLU   A 1 214 ? 55.758 -17.808 16.205 1.00 34.08  ?  906  GLU   A HA   1 
ATOM   3414 H  HB2  . GLU   A 1 214 ? 56.601 -15.768 18.288 1.00 38.90  ?  906  GLU   A HB2  1 
ATOM   3415 H  HB3  . GLU   A 1 214 ? 55.321 -15.544 17.143 1.00 38.90  ?  906  GLU   A HB3  1 
ATOM   3416 H  HG2  . GLU   A 1 214 ? 54.044 -17.432 18.102 1.00 41.23  ?  906  GLU   A HG2  1 
ATOM   3417 H  HG3  . GLU   A 1 214 ? 55.311 -17.738 19.263 1.00 41.23  ?  906  GLU   A HG3  1 
ATOM   3418 N  N    . LEU   A 1 215 ? 58.469 -15.942 16.027 1.00 40.09  ?  907  LEU   A N    1 
ATOM   3419 C  CA   . LEU   A 1 215 ? 59.255 -15.168 15.064 1.00 34.45  ?  907  LEU   A CA   1 
ATOM   3420 C  C    . LEU   A 1 215 ? 59.644 -15.985 13.838 1.00 41.05  ?  907  LEU   A C    1 
ATOM   3421 O  O    . LEU   A 1 215 ? 59.489 -15.532 12.704 1.00 30.60  ?  907  LEU   A O    1 
ATOM   3422 C  CB   . LEU   A 1 215 ? 60.521 -14.564 15.675 1.00 32.93  ?  907  LEU   A CB   1 
ATOM   3423 C  CG   . LEU   A 1 215 ? 60.355 -13.734 16.950 1.00 35.82  ?  907  LEU   A CG   1 
ATOM   3424 C  CD1  . LEU   A 1 215 ? 61.675 -13.093 17.348 1.00 22.95  ?  907  LEU   A CD1  1 
ATOM   3425 C  CD2  . LEU   A 1 215 ? 59.242 -12.700 16.876 1.00 25.37  ?  907  LEU   A CD2  1 
ATOM   3426 H  H    . LEU   A 1 215 ? 58.851 -16.157 16.944 1.00 42.09  ?  907  LEU   A H    1 
ATOM   3427 H  HA   . LEU   A 1 215 ? 58.632 -14.345 14.707 1.00 36.45  ?  907  LEU   A HA   1 
ATOM   3428 H  HB2  . LEU   A 1 215 ? 61.243 -15.357 15.879 1.00 34.93  ?  907  LEU   A HB2  1 
ATOM   3429 H  HB3  . LEU   A 1 215 ? 60.993 -13.936 14.918 1.00 34.93  ?  907  LEU   A HB3  1 
ATOM   3430 H  HG   . LEU   A 1 215 ? 60.106 -14.415 17.755 1.00 37.82  ?  907  LEU   A HG   1 
ATOM   3431 H  HD11 . LEU   A 1 215 ? 61.596 -12.590 18.312 1.00 24.95  ?  907  LEU   A HD11 1 
ATOM   3432 H  HD12 . LEU   A 1 215 ? 62.466 -13.839 17.441 1.00 24.95  ?  907  LEU   A HD12 1 
ATOM   3433 H  HD13 . LEU   A 1 215 ? 62.002 -12.356 16.615 1.00 24.95  ?  907  LEU   A HD13 1 
ATOM   3434 H  HD21 . LEU   A 1 215 ? 59.176 -12.135 17.806 1.00 27.37  ?  907  LEU   A HD21 1 
ATOM   3435 H  HD22 . LEU   A 1 215 ? 59.413 -11.997 16.060 1.00 27.37  ?  907  LEU   A HD22 1 
ATOM   3436 H  HD23 . LEU   A 1 215 ? 58.267 -13.162 16.726 1.00 27.37  ?  907  LEU   A HD23 1 
ATOM   3437 N  N    . MET   A 1 216 ? 60.090 -17.215 14.073 1.00 38.97  ?  908  MET   A N    1 
ATOM   3438 C  CA   . MET   A 1 216 ? 60.615 -18.036 12.983 1.00 35.42  ?  908  MET   A CA   1 
ATOM   3439 C  C    . MET   A 1 216 ? 59.530 -18.629 12.096 1.00 38.96  ?  908  MET   A C    1 
ATOM   3440 O  O    . MET   A 1 216 ? 59.796 -19.067 10.977 1.00 37.43  ?  908  MET   A O    1 
ATOM   3441 C  CB   . MET   A 1 216 ? 61.459 -19.186 13.528 1.00 26.36  ?  908  MET   A CB   1 
ATOM   3442 C  CG   . MET   A 1 216 ? 62.690 -18.763 14.328 1.00 22.81  ?  908  MET   A CG   1 
ATOM   3443 S  SD   . MET   A 1 216 ? 63.789 -17.682 13.432 1.00 32.96  ?  908  MET   A SD   1 
ATOM   3444 C  CE   . MET   A 1 216 ? 64.951 -17.271 14.727 1.00 23.98  ?  908  MET   A CE   1 
ATOM   3445 H  H    . MET   A 1 216 ? 60.190 -17.523 15.040 1.00 40.97  ?  908  MET   A H    1 
ATOM   3446 H  HA   . MET   A 1 216 ? 61.234 -17.413 12.336 1.00 37.42  ?  908  MET   A HA   1 
ATOM   3447 H  HB2  . MET   A 1 216 ? 60.840 -19.831 14.153 1.00 28.36  ?  908  MET   A HB2  1 
ATOM   3448 H  HB3  . MET   A 1 216 ? 61.795 -19.802 12.694 1.00 28.36  ?  908  MET   A HB3  1 
ATOM   3449 H  HG2  . MET   A 1 216 ? 62.409 -18.253 15.241 1.00 24.81  ?  908  MET   A HG2  1 
ATOM   3450 H  HG3  . MET   A 1 216 ? 63.267 -19.633 14.631 1.00 24.81  ?  908  MET   A HG3  1 
ATOM   3451 H  HE1  . MET   A 1 216 ? 65.647 -16.501 14.397 1.00 25.98  ?  908  MET   A HE1  1 
ATOM   3452 H  HE2  . MET   A 1 216 ? 64.417 -16.890 15.596 1.00 25.98  ?  908  MET   A HE2  1 
ATOM   3453 H  HE3  . MET   A 1 216 ? 65.523 -18.149 15.027 1.00 25.98  ?  908  MET   A HE3  1 
ATOM   3454 N  N    . THR   A 1 217 ? 58.303 -18.639 12.592 1.00 37.85  ?  909  THR   A N    1 
ATOM   3455 C  CA   . THR   A 1 217 ? 57.143 -19.017 11.783 1.00 38.67  ?  909  THR   A CA   1 
ATOM   3456 C  C    . THR   A 1 217 ? 56.412 -17.809 11.208 1.00 32.86  ?  909  THR   A C    1 
ATOM   3457 O  O    . THR   A 1 217 ? 55.343 -17.953 10.611 1.00 46.87  ?  909  THR   A O    1 
ATOM   3458 C  CB   . THR   A 1 217 ? 56.158 -19.853 12.605 1.00 32.97  ?  909  THR   A CB   1 
ATOM   3459 O  OG1  . THR   A 1 217 ? 55.655 -19.158 13.740 1.00 44.58  ?  909  THR   A OG1  1 
ATOM   3460 C  CG2  . THR   A 1 217 ? 56.734 -21.184 13.033 1.00 31.02  ?  909  THR   A CG2  1 
ATOM   3461 H  H    . THR   A 1 217 ? 58.148 -18.325 13.543 1.00 39.85  ?  909  THR   A H    1 
ATOM   3462 H  HA   . THR   A 1 217 ? 57.437 -19.623 10.924 1.00 40.67  ?  909  THR   A HA   1 
ATOM   3463 H  HB   . THR   A 1 217 ? 55.302 -20.095 11.974 1.00 34.97  ?  909  THR   A HB   1 
ATOM   3464 H  HG1  . THR   A 1 217 ? 56.333 -19.196 14.418 1.00 46.58  ?  909  THR   A HG1  1 
ATOM   3465 H  HG21 . THR   A 1 217 ? 55.990 -21.760 13.578 1.00 33.02  ?  909  THR   A HG21 1 
ATOM   3466 H  HG22 . THR   A 1 217 ? 57.023 -21.781 12.170 1.00 33.02  ?  909  THR   A HG22 1 
ATOM   3467 H  HG23 . THR   A 1 217 ? 57.607 -21.081 13.674 1.00 33.02  ?  909  THR   A HG23 1 
ATOM   3468 N  N    . PHE   A 1 218 ? 56.949 -16.613 11.423 1.00 38.29  ?  910  PHE   A N    1 
ATOM   3469 C  CA   . PHE   A 1 218 ? 56.359 -15.388 10.899 1.00 40.51  ?  910  PHE   A CA   1 
ATOM   3470 C  C    . PHE   A 1 218 ? 55.005 -15.038 11.517 1.00 48.36  ?  910  PHE   A C    1 
ATOM   3471 O  O    . PHE   A 1 218 ? 54.114 -14.465 10.878 1.00 51.52  ?  910  PHE   A O    1 
ATOM   3472 C  CB   . PHE   A 1 218 ? 56.386 -15.303 9.383  1.00 38.38  ?  910  PHE   A CB   1 
ATOM   3473 C  CG   . PHE   A 1 218 ? 57.782 -15.378 8.789  1.00 46.33  ?  910  PHE   A CG   1 
ATOM   3474 C  CD1  . PHE   A 1 218 ? 58.579 -14.217 8.709  1.00 37.20  ?  910  PHE   A CD1  1 
ATOM   3475 C  CD2  . PHE   A 1 218 ? 58.285 -16.611 8.323  1.00 32.93  ?  910  PHE   A CD2  1 
ATOM   3476 C  CE1  . PHE   A 1 218 ? 59.875 -14.290 8.162  1.00 39.44  ?  910  PHE   A CE1  1 
ATOM   3477 C  CE2  . PHE   A 1 218 ? 59.582 -16.681 7.777  1.00 32.29  ?  910  PHE   A CE2  1 
ATOM   3478 C  CZ   . PHE   A 1 218 ? 60.375 -15.521 7.696  1.00 40.91  ?  910  PHE   A CZ   1 
ATOM   3479 H  H    . PHE   A 1 218 ? 57.834 -16.538 11.914 1.00 40.29  ?  910  PHE   A H    1 
ATOM   3480 H  HA   . PHE   A 1 218 ? 57.022 -14.602 11.259 1.00 42.51  ?  910  PHE   A HA   1 
ATOM   3481 H  HB2  . PHE   A 1 218 ? 55.752 -16.064 8.929  1.00 40.38  ?  910  PHE   A HB2  1 
ATOM   3482 H  HB3  . PHE   A 1 218 ? 55.956 -14.350 9.086  1.00 40.38  ?  910  PHE   A HB3  1 
ATOM   3483 H  HD1  . PHE   A 1 218 ? 58.198 -13.271 9.068  1.00 39.20  ?  910  PHE   A HD1  1 
ATOM   3484 H  HD2  . PHE   A 1 218 ? 57.678 -17.503 8.386  1.00 34.93  ?  910  PHE   A HD2  1 
ATOM   3485 H  HE1  . PHE   A 1 218 ? 60.487 -13.404 8.100  1.00 41.44  ?  910  PHE   A HE1  1 
ATOM   3486 H  HE2  . PHE   A 1 218 ? 59.967 -17.624 7.422  1.00 34.29  ?  910  PHE   A HE2  1 
ATOM   3487 H  HZ   . PHE   A 1 218 ? 61.370 -15.575 7.277  1.00 42.91  ?  910  PHE   A HZ   1 
ATOM   3488 N  N    . GLY   A 1 219 ? 54.850 -15.431 12.772 1.00 35.12  ?  911  GLY   A N    1 
ATOM   3489 C  CA   . GLY   A 1 219 ? 53.705 -15.028 13.548 1.00 50.08  ?  911  GLY   A CA   1 
ATOM   3490 C  C    . GLY   A 1 219 ? 52.628 -16.076 13.633 1.00 47.70  ?  911  GLY   A C    1 
ATOM   3491 O  O    . GLY   A 1 219 ? 51.462 -15.734 13.821 1.00 63.72  ?  911  GLY   A O    1 
ATOM   3492 H  H    . GLY   A 1 219 ? 55.627 -15.881 13.259 1.00 37.12  ?  911  GLY   A H    1 
ATOM   3493 H  HA2  . GLY   A 1 219 ? 54.058 -14.850 14.564 1.00 52.08  ?  911  GLY   A HA2  1 
ATOM   3494 H  HA3  . GLY   A 1 219 ? 53.282 -14.084 13.213 1.00 52.08  ?  911  GLY   A HA3  1 
ATOM   3495 N  N    . SER   A 1 220 ? 52.978 -17.339 13.451 1.00 45.75  ?  912  SER   A N    1 
ATOM   3496 C  CA   . SER   A 1 220 ? 51.955 -18.381 13.507 1.00 45.78  ?  912  SER   A CA   1 
ATOM   3497 C  C    . SER   A 1 220 ? 51.538 -18.627 14.955 1.00 50.83  ?  912  SER   A C    1 
ATOM   3498 O  O    . SER   A 1 220 ? 52.296 -18.375 15.895 1.00 50.58  ?  912  SER   A O    1 
ATOM   3499 C  CB   . SER   A 1 220 ? 52.460 -19.681 12.876 1.00 39.44  ?  912  SER   A CB   1 
ATOM   3500 O  OG   . SER   A 1 220 ? 52.727 -19.507 11.483 1.00 44.95  ?  912  SER   A OG   1 
ATOM   3501 H  H    . SER   A 1 220 ? 53.952 -17.611 13.396 1.00 47.75  ?  912  SER   A H    1 
ATOM   3502 H  HA   . SER   A 1 220 ? 51.076 -18.060 12.942 1.00 47.78  ?  912  SER   A HA   1 
ATOM   3503 H  HB2  . SER   A 1 220 ? 53.336 -20.068 13.395 1.00 41.44  ?  912  SER   A HB2  1 
ATOM   3504 H  HB3  . SER   A 1 220 ? 51.698 -20.457 12.967 1.00 41.44  ?  912  SER   A HB3  1 
ATOM   3505 H  HG   . SER   A 1 220 ? 53.469 -18.917 11.381 1.00 46.95  ?  912  SER   A HG   1 
ATOM   3506 N  N    . LYS   A 1 221 ? 50.307 -19.088 15.144 1.00 55.53  ?  913  LYS   A N    1 
ATOM   3507 C  CA   . LYS   A 1 221 ? 49.804 -19.290 16.502 1.00 50.08  ?  913  LYS   A CA   1 
ATOM   3508 C  C    . LYS   A 1 221 ? 50.343 -20.614 17.047 1.00 44.47  ?  913  LYS   A C    1 
ATOM   3509 O  O    . LYS   A 1 221 ? 50.261 -21.622 16.335 1.00 51.44  ?  913  LYS   A O    1 
ATOM   3510 C  CB   . LYS   A 1 221 ? 48.279 -19.377 16.467 1.00 59.83  ?  913  LYS   A CB   1 
ATOM   3511 C  CG   . LYS   A 1 221 ? 47.579 -18.126 15.933 1.00 60.26  ?  913  LYS   A CG   1 
ATOM   3512 C  CD   . LYS   A 1 221 ? 46.085 -18.357 15.732 1.00 73.94  ?  913  LYS   A CD   1 
ATOM   3513 C  CE   . LYS   A 1 221 ? 45.369 -17.191 15.064 1.00 74.58  ?  913  LYS   A CE   1 
ATOM   3514 N  NZ   . LYS   A 1 221 ? 43.968 -17.537 14.761 1.00 85.99  1  913  LYS   A NZ   1 
ATOM   3515 H  H    . LYS   A 1 221 ? 49.716 -19.323 14.362 1.00 57.53  ?  913  LYS   A H    1 
ATOM   3516 H  HA   . LYS   A 1 221 ? 50.080 -18.437 17.120 1.00 52.08  ?  913  LYS   A HA   1 
ATOM   3517 H  HB2  . LYS   A 1 221 ? 47.984 -20.230 15.856 1.00 61.83  ?  913  LYS   A HB2  1 
ATOM   3518 H  HB3  . LYS   A 1 221 ? 47.903 -19.590 17.469 1.00 61.83  ?  913  LYS   A HB3  1 
ATOM   3519 H  HG2  . LYS   A 1 221 ? 47.743 -17.289 16.613 1.00 62.26  ?  913  LYS   A HG2  1 
ATOM   3520 H  HG3  . LYS   A 1 221 ? 48.015 -17.831 14.978 1.00 62.26  ?  913  LYS   A HG3  1 
ATOM   3521 H  HD2  . LYS   A 1 221 ? 45.947 -19.243 15.111 1.00 75.94  ?  913  LYS   A HD2  1 
ATOM   3522 H  HD3  . LYS   A 1 221 ? 45.613 -18.580 16.689 1.00 75.94  ?  913  LYS   A HD3  1 
ATOM   3523 H  HE2  . LYS   A 1 221 ? 45.390 -16.307 15.700 1.00 76.58  ?  913  LYS   A HE2  1 
ATOM   3524 H  HE3  . LYS   A 1 221 ? 45.862 -16.927 14.128 1.00 76.58  ?  913  LYS   A HE3  1 
ATOM   3525 H  HZ1  . LYS   A 1 221 ? 43.522 -16.767 14.286 1.00 87.99  ?  913  LYS   A HZ1  1 
ATOM   3526 H  HZ2  . LYS   A 1 221 ? 43.947 -18.354 14.169 1.00 87.99  ?  913  LYS   A HZ2  1 
ATOM   3527 H  HZ3  . LYS   A 1 221 ? 43.474 -17.736 15.618 1.00 87.99  ?  913  LYS   A HZ3  1 
ATOM   3528 N  N    . PRO   A 1 222 ? 50.909 -20.667 18.260 1.00 44.17  ?  914  PRO   A N    1 
ATOM   3529 C  CA   . PRO   A 1 222 ? 51.424 -21.913 18.802 1.00 40.53  ?  914  PRO   A CA   1 
ATOM   3530 C  C    . PRO   A 1 222 ? 50.301 -22.846 19.207 1.00 55.37  ?  914  PRO   A C    1 
ATOM   3531 O  O    . PRO   A 1 222 ? 49.336 -22.451 19.860 1.00 62.69  ?  914  PRO   A O    1 
ATOM   3532 C  CB   . PRO   A 1 222 ? 52.294 -21.510 19.980 1.00 39.08  ?  914  PRO   A CB   1 
ATOM   3533 C  CG   . PRO   A 1 222 ? 51.805 -20.121 20.386 1.00 38.80  ?  914  PRO   A CG   1 
ATOM   3534 C  CD   . PRO   A 1 222 ? 51.166 -19.521 19.128 1.00 37.21  ?  914  PRO   A CD   1 
ATOM   3535 H  HA   . PRO   A 1 222 ? 52.057 -22.403 18.060 1.00 42.53  ?  914  PRO   A HA   1 
ATOM   3536 H  HB2  . PRO   A 1 222 ? 52.279 -22.214 20.812 1.00 41.08  ?  914  PRO   A HB2  1 
ATOM   3537 H  HB3  . PRO   A 1 222 ? 53.331 -21.437 19.648 1.00 41.08  ?  914  PRO   A HB3  1 
ATOM   3538 H  HG2  . PRO   A 1 222 ? 51.045 -20.222 21.162 1.00 40.80  ?  914  PRO   A HG2  1 
ATOM   3539 H  HG3  . PRO   A 1 222 ? 52.601 -19.495 20.792 1.00 40.80  ?  914  PRO   A HG3  1 
ATOM   3540 H  HD2  . PRO   A 1 222 ? 50.253 -18.976 19.374 1.00 39.21  ?  914  PRO   A HD2  1 
ATOM   3541 H  HD3  . PRO   A 1 222 ? 51.862 -18.836 18.639 1.00 39.21  ?  914  PRO   A HD3  1 
ATOM   3542 N  N    . TYR   A 1 223 ? 50.424 -24.091 18.770 1.00 62.82  ?  915  TYR   A N    1 
ATOM   3543 C  CA   . TYR   A 1 223 ? 49.457 -25.139 19.068 1.00 52.89  ?  915  TYR   A CA   1 
ATOM   3544 C  C    . TYR   A 1 223 ? 48.082 -24.837 18.470 1.00 53.94  ?  915  TYR   A C    1 
ATOM   3545 O  O    . TYR   A 1 223 ? 47.052 -24.976 19.139 1.00 44.36  ?  915  TYR   A O    1 
ATOM   3546 C  CB   . TYR   A 1 223 ? 49.378 -25.486 20.550 1.00 50.53  ?  915  TYR   A CB   1 
ATOM   3547 C  CG   . TYR   A 1 223 ? 50.681 -25.628 21.313 1.00 50.00  ?  915  TYR   A CG   1 
ATOM   3548 C  CD1  . TYR   A 1 223 ? 51.386 -26.850 21.300 1.00 47.16  ?  915  TYR   A CD1  1 
ATOM   3549 C  CD2  . TYR   A 1 223 ? 51.178 -24.539 22.056 1.00 56.31  ?  915  TYR   A CD2  1 
ATOM   3550 C  CE1  . TYR   A 1 223 ? 52.578 -26.982 22.041 1.00 43.14  ?  915  TYR   A CE1  1 
ATOM   3551 C  CE2  . TYR   A 1 223 ? 52.367 -24.671 22.794 1.00 42.03  ?  915  TYR   A CE2  1 
ATOM   3552 C  CZ   . TYR   A 1 223 ? 53.064 -25.892 22.795 1.00 39.84  ?  915  TYR   A CZ   1 
ATOM   3553 O  OH   . TYR   A 1 223 ? 54.205 -26.023 23.532 1.00 44.98  ?  915  TYR   A OH   1 
ATOM   3554 H  H    . TYR   A 1 223 ? 51.199 -24.328 18.171 1.00 64.82  ?  915  TYR   A H    1 
ATOM   3555 H  HA   . TYR   A 1 223 ? 49.825 -26.026 18.551 1.00 54.89  ?  915  TYR   A HA   1 
ATOM   3556 H  HB2  . TYR   A 1 223 ? 48.793 -24.727 21.068 1.00 52.53  ?  915  TYR   A HB2  1 
ATOM   3557 H  HB3  . TYR   A 1 223 ? 48.816 -26.412 20.673 1.00 52.53  ?  915  TYR   A HB3  1 
ATOM   3558 H  HD1  . TYR   A 1 223 ? 51.009 -27.688 20.732 1.00 49.16  ?  915  TYR   A HD1  1 
ATOM   3559 H  HD2  . TYR   A 1 223 ? 50.642 -23.603 22.065 1.00 58.31  ?  915  TYR   A HD2  1 
ATOM   3560 H  HE1  . TYR   A 1 223 ? 53.115 -27.920 22.040 1.00 45.14  ?  915  TYR   A HE1  1 
ATOM   3561 H  HE2  . TYR   A 1 223 ? 52.738 -23.838 23.363 1.00 44.03  ?  915  TYR   A HE2  1 
ATOM   3562 H  HH   . TYR   A 1 223 ? 54.378 -25.255 24.093 1.00 46.98  ?  915  TYR   A HH   1 
ATOM   3563 N  N    . ASP   A 1 224 ? 48.077 -24.344 17.231 1.00 50.33  ?  916  ASP   A N    1 
ATOM   3564 C  CA   . ASP   A 1 224 ? 46.854 -23.812 16.635 1.00 64.63  ?  916  ASP   A CA   1 
ATOM   3565 C  C    . ASP   A 1 224 ? 45.778 -24.870 16.458 1.00 67.14  ?  916  ASP   A C    1 
ATOM   3566 O  O    . ASP   A 1 224 ? 45.969 -25.868 15.763 1.00 77.81  ?  916  ASP   A O    1 
ATOM   3567 C  CB   . ASP   A 1 224 ? 47.133 -23.133 15.291 1.00 63.31  ?  916  ASP   A CB   1 
ATOM   3568 C  CG   . ASP   A 1 224 ? 46.015 -22.215 14.819 1.00 71.52  ?  916  ASP   A CG   1 
ATOM   3569 O  OD1  . ASP   A 1 224 ? 45.133 -21.860 15.630 1.00 78.82  ?  916  ASP   A OD1  1 
ATOM   3570 O  OD2  . ASP   A 1 224 ? 46.012 -21.836 13.631 1.00 81.04  -1 916  ASP   A OD2  1 
ATOM   3571 H  H    . ASP   A 1 224 ? 48.949 -24.309 16.705 1.00 52.33  ?  916  ASP   A H    1 
ATOM   3572 H  HA   . ASP   A 1 224 ? 46.509 -23.049 17.338 1.00 66.63  ?  916  ASP   A HA   1 
ATOM   3573 H  HB2  . ASP   A 1 224 ? 48.031 -22.525 15.364 1.00 65.31  ?  916  ASP   A HB2  1 
ATOM   3574 H  HB3  . ASP   A 1 224 ? 47.338 -23.875 14.517 1.00 65.31  ?  916  ASP   A HB3  1 
ATOM   3575 N  N    . GLY   A 1 225 ? 44.666 -24.649 17.139 1.00 77.05  ?  917  GLY   A N    1 
ATOM   3576 C  CA   . GLY   A 1 225 ? 43.552 -25.579 17.075 1.00 79.33  ?  917  GLY   A CA   1 
ATOM   3577 C  C    . GLY   A 1 225 ? 43.417 -26.441 18.309 1.00 81.69  ?  917  GLY   A C    1 
ATOM   3578 O  O    . GLY   A 1 225 ? 42.363 -27.030 18.545 1.00 92.78  ?  917  GLY   A O    1 
ATOM   3579 H  H    . GLY   A 1 225 ? 44.580 -23.806 17.686 1.00 79.05  ?  917  GLY   A H    1 
ATOM   3580 H  HA2  . GLY   A 1 225 ? 42.640 -24.988 16.982 1.00 81.33  ?  917  GLY   A HA2  1 
ATOM   3581 H  HA3  . GLY   A 1 225 ? 43.575 -26.223 16.194 1.00 81.33  ?  917  GLY   A HA3  1 
ATOM   3582 N  N    . ILE   A 1 226 ? 44.479 -26.515 19.103 1.00 80.76  ?  918  ILE   A N    1 
ATOM   3583 C  CA   . ILE   A 1 226 ? 44.468 -27.326 20.310 1.00 78.12  ?  918  ILE   A CA   1 
ATOM   3584 C  C    . ILE   A 1 226 ? 43.963 -26.448 21.459 1.00 85.58  ?  918  ILE   A C    1 
ATOM   3585 O  O    . ILE   A 1 226 ? 44.512 -25.361 21.672 1.00 93.64  ?  918  ILE   A O    1 
ATOM   3586 C  CB   . ILE   A 1 226 ? 45.898 -27.807 20.616 1.00 72.92  ?  918  ILE   A CB   1 
ATOM   3587 C  CG1  . ILE   A 1 226 ? 46.587 -28.485 19.430 1.00 72.96  ?  918  ILE   A CG1  1 
ATOM   3588 C  CG2  . ILE   A 1 226 ? 45.990 -28.689 21.851 1.00 64.49  ?  918  ILE   A CG2  1 
ATOM   3589 C  CD1  . ILE   A 1 226 ? 45.882 -29.725 18.900 1.00 82.81  ?  918  ILE   A CD1  1 
ATOM   3590 H  H    . ILE   A 1 226 ? 45.308 -25.964 18.901 1.00 82.76  ?  918  ILE   A H    1 
ATOM   3591 H  HA   . ILE   A 1 226 ? 43.849 -28.208 20.156 1.00 80.12  ?  918  ILE   A HA   1 
ATOM   3592 H  HB   . ILE   A 1 226 ? 46.501 -26.925 20.839 1.00 74.92  ?  918  ILE   A HB   1 
ATOM   3593 H  HG12 . ILE   A 1 226 ? 46.708 -27.776 18.609 1.00 74.96  ?  918  ILE   A HG12 1 
ATOM   3594 H  HG13 . ILE   A 1 226 ? 47.605 -28.757 19.711 1.00 74.96  ?  918  ILE   A HG13 1 
ATOM   3595 H  HG21 . ILE   A 1 226 ? 47.012 -29.036 21.989 1.00 66.49  ?  918  ILE   A HG21 1 
ATOM   3596 H  HG22 . ILE   A 1 226 ? 45.722 -28.148 22.757 1.00 66.49  ?  918  ILE   A HG22 1 
ATOM   3597 H  HG23 . ILE   A 1 226 ? 45.344 -29.564 21.779 1.00 66.49  ?  918  ILE   A HG23 1 
ATOM   3598 H  HD11 . ILE   A 1 226 ? 46.453 -30.165 18.082 1.00 84.81  ?  918  ILE   A HD11 1 
ATOM   3599 H  HD12 . ILE   A 1 226 ? 45.771 -30.493 19.664 1.00 84.81  ?  918  ILE   A HD12 1 
ATOM   3600 H  HD13 . ILE   A 1 226 ? 44.893 -29.492 18.504 1.00 84.81  ?  918  ILE   A HD13 1 
ATOM   3601 N  N    . PRO   A 1 227 ? 42.941 -26.865 22.222 1.00 87.08  ?  919  PRO   A N    1 
ATOM   3602 C  CA   . PRO   A 1 227 ? 42.509 -26.104 23.385 1.00 78.23  ?  919  PRO   A CA   1 
ATOM   3603 C  C    . PRO   A 1 227 ? 43.496 -26.200 24.538 1.00 72.23  ?  919  PRO   A C    1 
ATOM   3604 O  O    . PRO   A 1 227 ? 44.182 -27.207 24.725 1.00 76.41  ?  919  PRO   A O    1 
ATOM   3605 C  CB   . PRO   A 1 227 ? 41.151 -26.676 23.745 1.00 81.15  ?  919  PRO   A CB   1 
ATOM   3606 C  CG   . PRO   A 1 227 ? 41.067 -28.051 23.077 1.00 82.11  ?  919  PRO   A CG   1 
ATOM   3607 C  CD   . PRO   A 1 227 ? 42.112 -28.039 21.956 1.00 87.30  ?  919  PRO   A CD   1 
ATOM   3608 H  HA   . PRO   A 1 227 ? 42.390 -25.055 23.107 1.00 80.23  ?  919  PRO   A HA   1 
ATOM   3609 H  HB2  . PRO   A 1 227 ? 40.968 -26.735 24.820 1.00 83.15  ?  919  PRO   A HB2  1 
ATOM   3610 H  HB3  . PRO   A 1 227 ? 40.374 -26.032 23.329 1.00 83.15  ?  919  PRO   A HB3  1 
ATOM   3611 H  HG2  . PRO   A 1 227 ? 41.280 -28.830 23.805 1.00 84.11  ?  919  PRO   A HG2  1 
ATOM   3612 H  HG3  . PRO   A 1 227 ? 40.067 -28.256 22.693 1.00 84.11  ?  919  PRO   A HG3  1 
ATOM   3613 H  HD2  . PRO   A 1 227 ? 42.698 -28.959 21.962 1.00 89.30  ?  919  PRO   A HD2  1 
ATOM   3614 H  HD3  . PRO   A 1 227 ? 41.628 -27.941 20.983 1.00 89.30  ?  919  PRO   A HD3  1 
ATOM   3615 N  N    . ALA   A 1 228 ? 43.543 -25.138 25.338 1.00 67.67  ?  920  ALA   A N    1 
ATOM   3616 C  CA   . ALA   A 1 228 ? 44.539 -24.998 26.404 1.00 59.95  ?  920  ALA   A CA   1 
ATOM   3617 C  C    . ALA   A 1 228 ? 44.507 -26.058 27.503 1.00 64.27  ?  920  ALA   A C    1 
ATOM   3618 O  O    . ALA   A 1 228 ? 45.490 -26.297 28.209 1.00 54.04  ?  920  ALA   A O    1 
ATOM   3619 C  CB   . ALA   A 1 228 ? 44.421 -23.625 27.031 1.00 65.63  ?  920  ALA   A CB   1 
ATOM   3620 H  H    . ALA   A 1 228 ? 42.938 -24.355 25.142 1.00 69.67  ?  920  ALA   A H    1 
ATOM   3621 H  HA   . ALA   A 1 228 ? 45.522 -25.048 25.939 1.00 61.95  ?  920  ALA   A HA   1 
ATOM   3622 H  HB1  . ALA   A 1 228 ? 45.185 -23.470 27.792 1.00 67.63  ?  920  ALA   A HB1  1 
ATOM   3623 H  HB2  . ALA   A 1 228 ? 44.547 -22.838 26.286 1.00 67.63  ?  920  ALA   A HB2  1 
ATOM   3624 H  HB3  . ALA   A 1 228 ? 43.450 -23.483 27.508 1.00 67.63  ?  920  ALA   A HB3  1 
ATOM   3625 N  N    . SER   A 1 229 ? 43.367 -26.722 27.604 1.00 67.98  ?  921  SER   A N    1 
ATOM   3626 C  CA   . SER   A 1 229 ? 43.201 -27.895 28.446 1.00 70.19  ?  921  SER   A CA   1 
ATOM   3627 C  C    . SER   A 1 229 ? 44.094 -29.080 28.088 1.00 75.15  ?  921  SER   A C    1 
ATOM   3628 O  O    . SER   A 1 229 ? 44.493 -29.854 28.963 1.00 70.90  ?  921  SER   A O    1 
ATOM   3629 C  CB   . SER   A 1 229 ? 41.721 -28.286 28.438 1.00 74.62  ?  921  SER   A CB   1 
ATOM   3630 O  OG   . SER   A 1 229 ? 41.166 -28.459 27.133 1.00 75.74  ?  921  SER   A OG   1 
ATOM   3631 H  H    . SER   A 1 229 ? 42.623 -26.525 26.951 1.00 69.98  ?  921  SER   A H    1 
ATOM   3632 H  HA   . SER   A 1 229 ? 43.464 -27.611 29.467 1.00 72.19  ?  921  SER   A HA   1 
ATOM   3633 H  HB2  . SER   A 1 229 ? 41.564 -29.200 29.014 1.00 76.62  ?  921  SER   A HB2  1 
ATOM   3634 H  HB3  . SER   A 1 229 ? 41.145 -27.510 28.945 1.00 76.62  ?  921  SER   A HB3  1 
ATOM   3635 H  HG   . SER   A 1 229 ? 41.447 -29.300 26.777 1.00 77.74  ?  921  SER   A HG   1 
ATOM   3636 N  N    . GLU   A 1 230 ? 44.429 -29.209 26.806 1.00 79.02  ?  922  GLU   A N    1 
ATOM   3637 C  CA   . GLU   A 1 230 ? 45.208 -30.363 26.368 1.00 81.21  ?  922  GLU   A CA   1 
ATOM   3638 C  C    . GLU   A 1 230 ? 46.701 -30.174 26.550 1.00 75.99  ?  922  GLU   A C    1 
ATOM   3639 O  O    . GLU   A 1 230 ? 47.432 -31.160 26.666 1.00 76.56  ?  922  GLU   A O    1 
ATOM   3640 C  CB   . GLU   A 1 230 ? 44.984 -30.643 24.879 1.00 89.12  ?  922  GLU   A CB   1 
ATOM   3641 C  CG   . GLU   A 1 230 ? 43.536 -30.603 24.390 1.00 95.97  ?  922  GLU   A CG   1 
ATOM   3642 C  CD   . GLU   A 1 230 ? 42.681 -31.528 25.227 1.00 104.06 ?  922  GLU   A CD   1 
ATOM   3643 O  OE1  . GLU   A 1 230 ? 41.698 -31.052 25.832 1.00 115.33 ?  922  GLU   A OE1  1 
ATOM   3644 O  OE2  . GLU   A 1 230 ? 42.985 -32.736 25.293 1.00 101.44 -1 922  GLU   A OE2  1 
ATOM   3645 H  H    . GLU   A 1 230 ? 44.124 -28.530 26.114 1.00 81.02  ?  922  GLU   A H    1 
ATOM   3646 H  HA   . GLU   A 1 230 ? 44.915 -31.253 26.931 1.00 83.21  ?  922  GLU   A HA   1 
ATOM   3647 H  HB2  . GLU   A 1 230 ? 45.537 -29.916 24.286 1.00 91.12  ?  922  GLU   A HB2  1 
ATOM   3648 H  HB3  . GLU   A 1 230 ? 45.421 -31.612 24.629 1.00 91.12  ?  922  GLU   A HB3  1 
ATOM   3649 H  HG2  . GLU   A 1 230 ? 43.160 -29.588 24.458 1.00 97.97  ?  922  GLU   A HG2  1 
ATOM   3650 H  HG3  . GLU   A 1 230 ? 43.475 -30.901 23.344 1.00 97.97  ?  922  GLU   A HG3  1 
ATOM   3651 N  N    . ILE   A 1 231 ? 47.131 -28.911 26.550 1.00 65.08  ?  923  ILE   A N    1 
ATOM   3652 C  CA   . ILE   A 1 231 ? 48.540 -28.534 26.452 1.00 52.14  ?  923  ILE   A CA   1 
ATOM   3653 C  C    . ILE   A 1 231 ? 49.418 -29.201 27.491 1.00 59.98  ?  923  ILE   A C    1 
ATOM   3654 O  O    . ILE   A 1 231 ? 50.440 -29.794 27.154 1.00 70.64  ?  923  ILE   A O    1 
ATOM   3655 C  CB   . ILE   A 1 231 ? 48.705 -27.004 26.400 1.00 49.02  ?  923  ILE   A CB   1 
ATOM   3656 C  CG1  . ILE   A 1 231 ? 47.951 -26.372 25.227 1.00 53.39  ?  923  ILE   A CG1  1 
ATOM   3657 C  CG2  . ILE   A 1 231 ? 50.154 -26.515 26.430 1.00 51.53  ?  923  ILE   A CG2  1 
ATOM   3658 C  CD1  . ILE   A 1 231 ? 48.466 -26.751 23.845 1.00 68.35  ?  923  ILE   A CD1  1 
ATOM   3659 H  H    . ILE   A 1 231 ? 46.435 -28.182 26.489 1.00 67.08  ?  923  ILE   A H    1 
ATOM   3660 H  HA   . ILE   A 1 231 ? 48.893 -28.929 25.499 1.00 54.14  ?  923  ILE   A HA   1 
ATOM   3661 H  HB   . ILE   A 1 231 ? 48.242 -26.607 27.305 1.00 51.02  ?  923  ILE   A HB   1 
ATOM   3662 H  HG12 . ILE   A 1 231 ? 46.896 -26.635 25.274 1.00 55.39  ?  923  ILE   A HG12 1 
ATOM   3663 H  HG13 . ILE   A 1 231 ? 47.989 -25.286 25.327 1.00 55.39  ?  923  ILE   A HG13 1 
ATOM   3664 H  HG21 . ILE   A 1 231 ? 50.216 -25.435 26.286 1.00 53.53  ?  923  ILE   A HG21 1 
ATOM   3665 H  HG22 . ILE   A 1 231 ? 50.634 -26.719 27.387 1.00 53.53  ?  923  ILE   A HG22 1 
ATOM   3666 H  HG23 . ILE   A 1 231 ? 50.764 -26.984 25.656 1.00 53.53  ?  923  ILE   A HG23 1 
ATOM   3667 H  HD11 . ILE   A 1 231 ? 47.923 -26.211 23.071 1.00 70.35  ?  923  ILE   A HD11 1 
ATOM   3668 H  HD12 . ILE   A 1 231 ? 49.523 -26.512 23.729 1.00 70.35  ?  923  ILE   A HD12 1 
ATOM   3669 H  HD13 . ILE   A 1 231 ? 48.341 -27.813 23.639 1.00 70.35  ?  923  ILE   A HD13 1 
ATOM   3670 N  N    . SER   A 1 232 ? 48.962 -29.190 28.736 1.00 55.56  ?  924  SER   A N    1 
ATOM   3671 C  CA   . SER   A 1 232 ? 49.687 -29.886 29.800 1.00 61.85  ?  924  SER   A CA   1 
ATOM   3672 C  C    . SER   A 1 232 ? 49.941 -31.371 29.548 1.00 60.82  ?  924  SER   A C    1 
ATOM   3673 O  O    . SER   A 1 232 ? 51.042 -31.870 29.769 1.00 60.07  ?  924  SER   A O    1 
ATOM   3674 C  CB   . SER   A 1 232 ? 49.026 -29.657 31.157 1.00 63.19  ?  924  SER   A CB   1 
ATOM   3675 O  OG   . SER   A 1 232 ? 47.712 -30.205 31.266 1.00 76.46  ?  924  SER   A OG   1 
ATOM   3676 H  H    . SER   A 1 232 ? 48.095 -28.717 28.934 1.00 57.56  ?  924  SER   A H    1 
ATOM   3677 H  HA   . SER   A 1 232 ? 50.673 -29.419 29.849 1.00 63.85  ?  924  SER   A HA   1 
ATOM   3678 H  HB2  . SER   A 1 232 ? 49.646 -30.109 31.931 1.00 65.19  ?  924  SER   A HB2  1 
ATOM   3679 H  HB3  . SER   A 1 232 ? 48.990 -28.592 31.386 1.00 65.19  ?  924  SER   A HB3  1 
ATOM   3680 H  HG   . SER   A 1 232 ? 47.122 -29.741 30.687 1.00 78.46  ?  924  SER   A HG   1 
ATOM   3681 N  N    . SER   A 1 233 ? 48.940 -32.047 28.996 1.00 56.71  ?  925  SER   A N    1 
ATOM   3682 C  CA   . SER   A 1 233 ? 49.046 -33.485 28.771 1.00 70.64  ?  925  SER   A CA   1 
ATOM   3683 C  C    . SER   A 1 233 ? 49.892 -33.800 27.544 1.00 64.31  ?  925  SER   A C    1 
ATOM   3684 O  O    . SER   A 1 233 ? 50.685 -34.742 27.533 1.00 57.50  ?  925  SER   A O    1 
ATOM   3685 C  CB   . SER   A 1 233 ? 47.655 -34.085 28.569 1.00 72.70  ?  925  SER   A CB   1 
ATOM   3686 O  OG   . SER   A 1 233 ? 46.907 -34.082 29.778 1.00 96.49  ?  925  SER   A OG   1 
ATOM   3687 H  H    . SER   A 1 233 ? 48.111 -31.555 28.694 1.00 58.71  ?  925  SER   A H    1 
ATOM   3688 H  HA   . SER   A 1 233 ? 49.511 -33.969 29.632 1.00 72.64  ?  925  SER   A HA   1 
ATOM   3689 H  HB2  . SER   A 1 233 ? 47.102 -33.554 27.794 1.00 74.70  ?  925  SER   A HB2  1 
ATOM   3690 H  HB3  . SER   A 1 233 ? 47.734 -35.123 28.239 1.00 74.70  ?  925  SER   A HB3  1 
ATOM   3691 H  HG   . SER   A 1 233 ? 46.915 -33.199 30.130 1.00 98.49  ?  925  SER   A HG   1 
ATOM   3692 N  N    . ILE   A 1 234 ? 49.741 -32.965 26.527 1.00 57.45  ?  926  ILE   A N    1 
ATOM   3693 C  CA   . ILE   A 1 234 ? 50.606 -32.943 25.357 1.00 55.66  ?  926  ILE   A CA   1 
ATOM   3694 C  C    . ILE   A 1 234 ? 52.087 -32.812 25.710 1.00 62.60  ?  926  ILE   A C    1 
ATOM   3695 O  O    . ILE   A 1 234 ? 52.925 -33.592 25.248 1.00 71.27  ?  926  ILE   A O    1 
ATOM   3696 C  CB   . ILE   A 1 234 ? 50.052 -31.881 24.387 1.00 53.70  ?  926  ILE   A CB   1 
ATOM   3697 C  CG1  . ILE   A 1 234 ? 48.802 -32.434 23.698 1.00 40.12  ?  926  ILE   A CG1  1 
ATOM   3698 C  CG2  . ILE   A 1 234 ? 51.049 -31.328 23.378 1.00 61.07  ?  926  ILE   A CG2  1 
ATOM   3699 C  CD1  . ILE   A 1 234 ? 47.992 -31.405 22.930 1.00 54.27  ?  926  ILE   A CD1  1 
ATOM   3700 H  H    . ILE   A 1 234 ? 49.074 -32.205 26.628 1.00 59.45  ?  926  ILE   A H    1 
ATOM   3701 H  HA   . ILE   A 1 234 ? 50.521 -33.920 24.875 1.00 57.66  ?  926  ILE   A HA   1 
ATOM   3702 H  HB   . ILE   A 1 234 ? 49.743 -31.023 24.981 1.00 55.70  ?  926  ILE   A HB   1 
ATOM   3703 H  HG12 . ILE   A 1 234 ? 49.079 -33.249 23.027 1.00 42.12  ?  926  ILE   A HG12 1 
ATOM   3704 H  HG13 . ILE   A 1 234 ? 48.138 -32.878 24.441 1.00 42.12  ?  926  ILE   A HG13 1 
ATOM   3705 H  HG21 . ILE   A 1 234 ? 50.599 -30.595 22.710 1.00 63.07  ?  926  ILE   A HG21 1 
ATOM   3706 H  HG22 . ILE   A 1 234 ? 51.885 -30.819 23.859 1.00 63.07  ?  926  ILE   A HG22 1 
ATOM   3707 H  HG23 . ILE   A 1 234 ? 51.452 -32.130 22.766 1.00 63.07  ?  926  ILE   A HG23 1 
ATOM   3708 H  HD11 . ILE   A 1 234 ? 47.046 -31.835 22.598 1.00 56.27  ?  926  ILE   A HD11 1 
ATOM   3709 H  HD12 . ILE   A 1 234 ? 47.765 -30.547 23.561 1.00 56.27  ?  926  ILE   A HD12 1 
ATOM   3710 H  HD13 . ILE   A 1 234 ? 48.513 -31.055 22.040 1.00 56.27  ?  926  ILE   A HD13 1 
ATOM   3711 N  N    . LEU   A 1 235 ? 52.380 -31.873 26.603 1.00 56.24  ?  927  LEU   A N    1 
ATOM   3712 C  CA   . LEU   A 1 235 ? 53.752 -31.653 27.028 1.00 54.90  ?  927  LEU   A CA   1 
ATOM   3713 C  C    . LEU   A 1 235 ? 54.289 -32.755 27.922 1.00 53.99  ?  927  LEU   A C    1 
ATOM   3714 O  O    . LEU   A 1 235 ? 55.452 -33.144 27.796 1.00 61.42  ?  927  LEU   A O    1 
ATOM   3715 C  CB   . LEU   A 1 235 ? 53.867 -30.337 27.781 1.00 49.45  ?  927  LEU   A CB   1 
ATOM   3716 C  CG   . LEU   A 1 235 ? 53.576 -29.097 26.947 1.00 59.72  ?  927  LEU   A CG   1 
ATOM   3717 C  CD1  . LEU   A 1 235 ? 53.407 -27.885 27.850 1.00 54.33  ?  927  LEU   A CD1  1 
ATOM   3718 C  CD2  . LEU   A 1 235 ? 54.609 -28.878 25.859 1.00 49.07  ?  927  LEU   A CD2  1 
ATOM   3719 H  H    . LEU   A 1 235 ? 51.654 -31.237 26.922 1.00 58.24  ?  927  LEU   A H    1 
ATOM   3720 H  HA   . LEU   A 1 235 ? 54.385 -31.618 26.141 1.00 56.90  ?  927  LEU   A HA   1 
ATOM   3721 H  HB2  . LEU   A 1 235 ? 53.164 -30.375 28.612 1.00 51.45  ?  927  LEU   A HB2  1 
ATOM   3722 H  HB3  . LEU   A 1 235 ? 54.859 -30.239 28.228 1.00 51.45  ?  927  LEU   A HB3  1 
ATOM   3723 H  HG   . LEU   A 1 235 ? 52.636 -29.220 26.418 1.00 61.72  ?  927  LEU   A HG   1 
ATOM   3724 H  HD11 . LEU   A 1 235 ? 53.218 -26.988 27.261 1.00 56.33  ?  927  LEU   A HD11 1 
ATOM   3725 H  HD12 . LEU   A 1 235 ? 52.558 -28.010 28.523 1.00 56.33  ?  927  LEU   A HD12 1 
ATOM   3726 H  HD13 . LEU   A 1 235 ? 54.290 -27.703 28.462 1.00 56.33  ?  927  LEU   A HD13 1 
ATOM   3727 H  HD21 . LEU   A 1 235 ? 54.491 -27.901 25.390 1.00 51.07  ?  927  LEU   A HD21 1 
ATOM   3728 H  HD22 . LEU   A 1 235 ? 55.626 -28.956 26.240 1.00 51.07  ?  927  LEU   A HD22 1 
ATOM   3729 H  HD23 . LEU   A 1 235 ? 54.499 -29.612 25.062 1.00 51.07  ?  927  LEU   A HD23 1 
ATOM   3730 N  N    . GLU   A 1 236 ? 53.432 -33.290 28.789 1.00 63.81  ?  928  GLU   A N    1 
ATOM   3731 C  CA   . GLU   A 1 236 ? 53.806 -34.422 29.634 1.00 59.27  ?  928  GLU   A CA   1 
ATOM   3732 C  C    . GLU   A 1 236 ? 54.092 -35.691 28.829 1.00 52.70  ?  928  GLU   A C    1 
ATOM   3733 O  O    . GLU   A 1 236 ? 54.979 -36.472 29.177 1.00 45.03  ?  928  GLU   A O    1 
ATOM   3734 C  CB   . GLU   A 1 236 ? 52.696 -34.704 30.648 1.00 63.24  ?  928  GLU   A CB   1 
ATOM   3735 C  CG   . GLU   A 1 236 ? 52.643 -33.700 31.801 1.00 76.71  ?  928  GLU   A CG   1 
ATOM   3736 C  CD   . GLU   A 1 236 ? 51.395 -33.931 32.629 1.00 77.00  ?  928  GLU   A CD   1 
ATOM   3737 O  OE1  . GLU   A 1 236 ? 50.285 -33.608 32.156 1.00 79.69  ?  928  GLU   A OE1  1 
ATOM   3738 O  OE2  . GLU   A 1 236 ? 51.512 -34.438 33.762 1.00 77.72  -1 928  GLU   A OE2  1 
ATOM   3739 H  H    . GLU   A 1 236 ? 52.510 -32.880 28.905 1.00 65.81  ?  928  GLU   A H    1 
ATOM   3740 H  HA   . GLU   A 1 236 ? 54.721 -34.171 30.175 1.00 61.27  ?  928  GLU   A HA   1 
ATOM   3741 H  HB2  . GLU   A 1 236 ? 51.736 -34.749 30.131 1.00 65.24  ?  928  GLU   A HB2  1 
ATOM   3742 H  HB3  . GLU   A 1 236 ? 52.840 -35.696 31.083 1.00 65.24  ?  928  GLU   A HB3  1 
ATOM   3743 H  HG2  . GLU   A 1 236 ? 53.523 -33.801 32.436 1.00 78.71  ?  928  GLU   A HG2  1 
ATOM   3744 H  HG3  . GLU   A 1 236 ? 52.642 -32.676 31.437 1.00 78.71  ?  928  GLU   A HG3  1 
ATOM   3745 N  N    . LYS   A 1 237 ? 53.367 -35.863 27.726 1.00 41.53  ?  929  LYS   A N    1 
ATOM   3746 C  CA   . LYS   A 1 237 ? 53.635 -36.951 26.790 1.00 56.75  ?  929  LYS   A CA   1 
ATOM   3747 C  C    . LYS   A 1 237 ? 54.816 -36.692 25.851 1.00 60.03  ?  929  LYS   A C    1 
ATOM   3748 O  O    . LYS   A 1 237 ? 55.212 -37.582 25.095 1.00 57.11  ?  929  LYS   A O    1 
ATOM   3749 C  CB   . LYS   A 1 237 ? 52.384 -37.221 25.953 1.00 62.22  ?  929  LYS   A CB   1 
ATOM   3750 C  CG   . LYS   A 1 237 ? 51.284 -37.905 26.759 1.00 77.75  ?  929  LYS   A CG   1 
ATOM   3751 C  CD   . LYS   A 1 237 ? 49.981 -38.054 25.987 1.00 78.13  ?  929  LYS   A CD   1 
ATOM   3752 C  CE   . LYS   A 1 237 ? 48.906 -38.750 26.808 1.00 78.99  ?  929  LYS   A CE   1 
ATOM   3753 N  NZ   . LYS   A 1 237 ? 47.655 -38.886 26.046 1.00 92.92  1  929  LYS   A NZ   1 
ATOM   3754 H  H    . LYS   A 1 237 ? 52.620 -35.207 27.518 1.00 43.53  ?  929  LYS   A H    1 
ATOM   3755 H  HA   . LYS   A 1 237 ? 53.881 -37.860 27.344 1.00 58.75  ?  929  LYS   A HA   1 
ATOM   3756 H  HB2  . LYS   A 1 237 ? 52.018 -36.285 25.528 1.00 64.22  ?  929  LYS   A HB2  1 
ATOM   3757 H  HB3  . LYS   A 1 237 ? 52.623 -37.862 25.101 1.00 64.22  ?  929  LYS   A HB3  1 
ATOM   3758 H  HG2  . LYS   A 1 237 ? 51.634 -38.886 27.084 1.00 79.75  ?  929  LYS   A HG2  1 
ATOM   3759 H  HG3  . LYS   A 1 237 ? 51.090 -37.340 27.671 1.00 79.75  ?  929  LYS   A HG3  1 
ATOM   3760 H  HD2  . LYS   A 1 237 ? 49.628 -37.066 25.686 1.00 80.13  ?  929  LYS   A HD2  1 
ATOM   3761 H  HD3  . LYS   A 1 237 ? 50.164 -38.614 25.068 1.00 80.13  ?  929  LYS   A HD3  1 
ATOM   3762 H  HE2  . LYS   A 1 237 ? 49.240 -39.744 27.107 1.00 80.99  ?  929  LYS   A HE2  1 
ATOM   3763 H  HE3  . LYS   A 1 237 ? 48.699 -38.191 27.722 1.00 80.99  ?  929  LYS   A HE3  1 
ATOM   3764 H  HZ1  . LYS   A 1 237 ? 46.975 -39.386 26.598 1.00 94.92  ?  929  LYS   A HZ1  1 
ATOM   3765 H  HZ2  . LYS   A 1 237 ? 47.295 -37.971 25.820 1.00 94.92  ?  929  LYS   A HZ2  1 
ATOM   3766 H  HZ3  . LYS   A 1 237 ? 47.834 -39.395 25.193 1.00 94.92  ?  929  LYS   A HZ3  1 
ATOM   3767 N  N    . GLY   A 1 238 ? 55.374 -35.489 25.878 1.00 54.00  ?  930  GLY   A N    1 
ATOM   3768 C  CA   . GLY   A 1 238 ? 56.679 -35.276 25.270 1.00 48.26  ?  930  GLY   A CA   1 
ATOM   3769 C  C    . GLY   A 1 238 ? 56.656 -34.565 23.936 1.00 44.52  ?  930  GLY   A C    1 
ATOM   3770 O  O    . GLY   A 1 238 ? 57.712 -34.367 23.335 1.00 53.54  ?  930  GLY   A O    1 
ATOM   3771 H  H    . GLY   A 1 238 ? 55.021 -34.789 26.519 1.00 56.00  ?  930  GLY   A H    1 
ATOM   3772 H  HA2  . GLY   A 1 238 ? 57.236 -34.639 25.954 1.00 50.26  ?  930  GLY   A HA2  1 
ATOM   3773 H  HA3  . GLY   A 1 238 ? 57.267 -36.192 25.182 1.00 50.26  ?  930  GLY   A HA3  1 
ATOM   3774 N  N    . GLU   A 1 239 ? 55.459 -34.197 23.479 1.00 41.34  ?  931  GLU   A N    1 
ATOM   3775 C  CA   . GLU   A 1 239 ? 55.295 -33.467 22.233 1.00 43.67  ?  931  GLU   A CA   1 
ATOM   3776 C  C    . GLU   A 1 239 ? 55.653 -31.998 22.413 1.00 55.76  ?  931  GLU   A C    1 
ATOM   3777 O  O    . GLU   A 1 239 ? 55.475 -31.417 23.492 1.00 46.30  ?  931  GLU   A O    1 
ATOM   3778 C  CB   . GLU   A 1 239 ? 53.860 -33.649 21.732 1.00 47.77  ?  931  GLU   A CB   1 
ATOM   3779 C  CG   . GLU   A 1 239 ? 53.326 -32.620 20.713 1.00 71.17  ?  931  GLU   A CG   1 
ATOM   3780 C  CD   . GLU   A 1 239 ? 52.035 -33.113 20.084 1.00 88.84  ?  931  GLU   A CD   1 
ATOM   3781 O  OE1  . GLU   A 1 239 ? 51.346 -33.961 20.692 1.00 91.82  ?  931  GLU   A OE1  1 
ATOM   3782 O  OE2  . GLU   A 1 239 ? 51.693 -32.650 18.975 1.00 91.22  -1 931  GLU   A OE2  1 
ATOM   3783 H  H    . GLU   A 1 239 ? 54.657 -34.292 24.089 1.00 43.34  ?  931  GLU   A H    1 
ATOM   3784 H  HA   . GLU   A 1 239 ? 55.968 -33.892 21.485 1.00 45.67  ?  931  GLU   A HA   1 
ATOM   3785 H  HB2  . GLU   A 1 239 ? 53.805 -34.648 21.297 1.00 49.77  ?  931  GLU   A HB2  1 
ATOM   3786 H  HB3  . GLU   A 1 239 ? 53.182 -33.662 22.586 1.00 49.77  ?  931  GLU   A HB3  1 
ATOM   3787 H  HG2  . GLU   A 1 239 ? 53.152 -31.655 21.189 1.00 73.17  ?  931  GLU   A HG2  1 
ATOM   3788 H  HG3  . GLU   A 1 239 ? 54.044 -32.459 19.909 1.00 73.17  ?  931  GLU   A HG3  1 
ATOM   3789 N  N    . ARG   A 1 240 ? 56.167 -31.411 21.341 1.00 39.63  ?  932  ARG   A N    1 
ATOM   3790 C  CA   . ARG   A 1 240 ? 56.530 -30.005 21.313 1.00 29.49  ?  932  ARG   A CA   1 
ATOM   3791 C  C    . ARG   A 1 240 ? 56.101 -29.386 20.005 1.00 29.19  ?  932  ARG   A C    1 
ATOM   3792 O  O    . ARG   A 1 240 ? 55.720 -30.086 19.064 1.00 55.16  ?  932  ARG   A O    1 
ATOM   3793 C  CB   . ARG   A 1 240 ? 58.014 -29.789 21.584 1.00 33.37  ?  932  ARG   A CB   1 
ATOM   3794 C  CG   . ARG   A 1 240 ? 58.515 -30.249 22.941 1.00 34.26  ?  932  ARG   A CG   1 
ATOM   3795 C  CD   . ARG   A 1 240 ? 57.940 -29.438 24.092 1.00 33.48  ?  932  ARG   A CD   1 
ATOM   3796 N  NE   . ARG   A 1 240 ? 58.555 -29.815 25.376 1.00 28.71  ?  932  ARG   A NE   1 
ATOM   3797 C  CZ   . ARG   A 1 240 ? 58.097 -30.796 26.165 1.00 37.04  ?  932  ARG   A CZ   1 
ATOM   3798 N  NH1  . ARG   A 1 240 ? 57.021 -31.514 25.813 1.00 32.64  ?  932  ARG   A NH1  1 
ATOM   3799 N  NH2  . ARG   A 1 240 ? 58.721 -31.056 27.308 1.00 24.77  1  932  ARG   A NH2  1 
ATOM   3800 H  H    . ARG   A 1 240 ? 56.184 -31.924 20.461 1.00 41.63  ?  932  ARG   A H    1 
ATOM   3801 H  HA   . ARG   A 1 240 ? 55.946 -29.467 22.061 1.00 31.49  ?  932  ARG   A HA   1 
ATOM   3802 H  HB2  . ARG   A 1 240 ? 58.574 -30.312 20.814 1.00 35.37  ?  932  ARG   A HB2  1 
ATOM   3803 H  HB3  . ARG   A 1 240 ? 58.270 -28.738 21.455 1.00 35.37  ?  932  ARG   A HB3  1 
ATOM   3804 H  HG2  . ARG   A 1 240 ? 58.316 -31.311 23.085 1.00 36.26  ?  932  ARG   A HG2  1 
ATOM   3805 H  HG3  . ARG   A 1 240 ? 59.602 -30.156 22.955 1.00 36.26  ?  932  ARG   A HG3  1 
ATOM   3806 H  HD2  . ARG   A 1 240 ? 58.174 -28.390 23.927 1.00 35.48  ?  932  ARG   A HD2  1 
ATOM   3807 H  HD3  . ARG   A 1 240 ? 56.856 -29.488 24.153 1.00 35.48  ?  932  ARG   A HD3  1 
ATOM   3808 H  HE   . ARG   A 1 240 ? 59.371 -29.290 25.672 1.00 30.71  ?  932  ARG   A HE   1 
ATOM   3809 H  HH11 . ARG   A 1 240 ? 56.542 -31.323 24.935 1.00 34.64  ?  932  ARG   A HH11 1 
ATOM   3810 H  HH12 . ARG   A 1 240 ? 56.677 -32.248 26.421 1.00 34.64  ?  932  ARG   A HH12 1 
ATOM   3811 H  HH21 . ARG   A 1 240 ? 59.528 -30.505 27.579 1.00 26.77  ?  932  ARG   A HH21 1 
ATOM   3812 H  HH22 . ARG   A 1 240 ? 58.400 -31.807 27.905 1.00 26.77  ?  932  ARG   A HH22 1 
ATOM   3813 N  N    . LEU   A 1 241 ? 56.188 -28.061 19.945 1.00 36.80  ?  933  LEU   A N    1 
ATOM   3814 C  CA   . LEU   A 1 241 ? 55.970 -27.313 18.706 1.00 38.92  ?  933  LEU   A CA   1 
ATOM   3815 C  C    . LEU   A 1 241 ? 56.895 -27.786 17.572 1.00 43.24  ?  933  LEU   A C    1 
ATOM   3816 O  O    . LEU   A 1 241 ? 58.050 -28.140 17.840 1.00 40.51  ?  933  LEU   A O    1 
ATOM   3817 C  CB   . LEU   A 1 241 ? 56.158 -25.812 18.947 1.00 37.20  ?  933  LEU   A CB   1 
ATOM   3818 C  CG   . LEU   A 1 241 ? 55.091 -25.123 19.796 1.00 43.92  ?  933  LEU   A CG   1 
ATOM   3819 C  CD1  . LEU   A 1 241 ? 55.595 -23.816 20.379 1.00 37.08  ?  933  LEU   A CD1  1 
ATOM   3820 C  CD2  . LEU   A 1 241 ? 53.816 -24.868 19.012 1.00 42.58  ?  933  LEU   A CD2  1 
ATOM   3821 H  H    . LEU   A 1 241 ? 56.463 -27.552 20.786 1.00 38.80  ?  933  LEU   A H    1 
ATOM   3822 H  HA   . LEU   A 1 241 ? 54.934 -27.503 18.432 1.00 40.92  ?  933  LEU   A HA   1 
ATOM   3823 H  HB2  . LEU   A 1 241 ? 57.128 -25.678 19.419 1.00 39.20  ?  933  LEU   A HB2  1 
ATOM   3824 H  HB3  . LEU   A 1 241 ? 56.234 -25.283 17.999 1.00 39.20  ?  933  LEU   A HB3  1 
ATOM   3825 H  HG   . LEU   A 1 241 ? 54.850 -25.774 20.635 1.00 45.92  ?  933  LEU   A HG   1 
ATOM   3826 H  HD11 . LEU   A 1 241 ? 54.844 -23.356 21.023 1.00 39.08  ?  933  LEU   A HD11 1 
ATOM   3827 H  HD12 . LEU   A 1 241 ? 56.484 -23.973 20.989 1.00 39.08  ?  933  LEU   A HD12 1 
ATOM   3828 H  HD13 . LEU   A 1 241 ? 55.848 -23.099 19.597 1.00 39.08  ?  933  LEU   A HD13 1 
ATOM   3829 H  HD21 . LEU   A 1 241 ? 53.069 -24.397 19.650 1.00 44.58  ?  933  LEU   A HD21 1 
ATOM   3830 H  HD22 . LEU   A 1 241 ? 53.993 -24.210 18.160 1.00 44.58  ?  933  LEU   A HD22 1 
ATOM   3831 H  HD23 . LEU   A 1 241 ? 53.378 -25.794 18.641 1.00 44.58  ?  933  LEU   A HD23 1 
ATOM   3832 N  N    . PRO   A 1 242 ? 56.436 -27.811 16.314 1.00 49.56  ?  934  PRO   A N    1 
ATOM   3833 C  CA   . PRO   A 1 242 ? 57.215 -28.364 15.206 1.00 47.71  ?  934  PRO   A CA   1 
ATOM   3834 C  C    . PRO   A 1 242 ? 58.347 -27.459 14.747 1.00 49.02  ?  934  PRO   A C    1 
ATOM   3835 O  O    . PRO   A 1 242 ? 58.257 -26.238 14.881 1.00 35.19  ?  934  PRO   A O    1 
ATOM   3836 C  CB   . PRO   A 1 242 ? 56.192 -28.518 14.090 1.00 39.65  ?  934  PRO   A CB   1 
ATOM   3837 C  CG   . PRO   A 1 242 ? 55.141 -27.445 14.367 1.00 39.16  ?  934  PRO   A CG   1 
ATOM   3838 C  CD   . PRO   A 1 242 ? 55.123 -27.315 15.895 1.00 41.82  ?  934  PRO   A CD   1 
ATOM   3839 H  HA   . PRO   A 1 242 ? 57.621 -29.340 15.483 1.00 49.71  ?  934  PRO   A HA   1 
ATOM   3840 H  HB2  . PRO   A 1 242 ? 56.615 -28.433 13.086 1.00 41.65  ?  934  PRO   A HB2  1 
ATOM   3841 H  HB3  . PRO   A 1 242 ? 55.731 -29.504 14.158 1.00 41.65  ?  934  PRO   A HB3  1 
ATOM   3842 H  HG2  . PRO   A 1 242 ? 55.462 -26.502 13.921 1.00 41.16  ?  934  PRO   A HG2  1 
ATOM   3843 H  HG3  . PRO   A 1 242 ? 54.163 -27.690 13.951 1.00 41.16  ?  934  PRO   A HG3  1 
ATOM   3844 H  HD2  . PRO   A 1 242 ? 54.942 -26.287 16.211 1.00 43.82  ?  934  PRO   A HD2  1 
ATOM   3845 H  HD3  . PRO   A 1 242 ? 54.341 -27.954 16.309 1.00 43.82  ?  934  PRO   A HD3  1 
ATOM   3846 N  N    . GLN   A 1 243 ? 59.377 -28.060 14.151 1.00 47.58  ?  935  GLN   A N    1 
ATOM   3847 C  CA   . GLN   A 1 243 ? 60.481 -27.315 13.534 1.00 39.57  ?  935  GLN   A CA   1 
ATOM   3848 C  C    . GLN   A 1 243 ? 59.989 -26.351 12.461 1.00 31.84  ?  935  GLN   A C    1 
ATOM   3849 O  O    . GLN   A 1 243 ? 59.409 -26.816 11.476 1.00 47.78  ?  935  GLN   A O    1 
ATOM   3850 C  CB   . GLN   A 1 243 ? 61.516 -28.293 12.970 1.00 29.67  ?  935  GLN   A CB   1 
ATOM   3851 C  CG   . GLN   A 1 243 ? 62.809 -27.676 12.414 1.00 29.82  ?  935  GLN   A CG   1 
ATOM   3852 C  CD   . GLN   A 1 243 ? 63.932 -28.689 12.248 1.00 40.92  ?  935  GLN   A CD   1 
ATOM   3853 O  OE1  . GLN   A 1 243 ? 63.880 -29.806 12.761 1.00 43.30  ?  935  GLN   A OE1  1 
ATOM   3854 N  NE2  . GLN   A 1 243 ? 64.961 -28.311 11.527 1.00 27.51  ?  935  GLN   A NE2  1 
ATOM   3855 H  H    . GLN   A 1 243 ? 59.397 -29.067 14.099 1.00 49.58  ?  935  GLN   A H    1 
ATOM   3856 H  HA   . GLN   A 1 243 ? 60.978 -26.773 14.328 1.00 41.57  ?  935  GLN   A HA   1 
ATOM   3857 H  HB2  . GLN   A 1 243 ? 61.765 -28.991 13.768 1.00 31.67  ?  935  GLN   A HB2  1 
ATOM   3858 H  HB3  . GLN   A 1 243 ? 61.060 -28.907 12.191 1.00 31.67  ?  935  GLN   A HB3  1 
ATOM   3859 H  HG2  . GLN   A 1 243 ? 62.612 -27.198 11.452 1.00 31.82  ?  935  GLN   A HG2  1 
ATOM   3860 H  HG3  . GLN   A 1 243 ? 63.162 -26.893 13.082 1.00 31.82  ?  935  GLN   A HG3  1 
ATOM   3861 H  HE21 . GLN   A 1 243 ? 64.982 -27.380 11.108 1.00 29.51  ?  935  GLN   A HE21 1 
ATOM   3862 H  HE22 . GLN   A 1 243 ? 65.727 -28.958 11.363 1.00 29.51  ?  935  GLN   A HE22 1 
ATOM   3863 N  N    . PRO   A 1 244 ? 60.149 -25.025 12.621 1.00 35.51  ?  936  PRO   A N    1 
ATOM   3864 C  CA   . PRO   A 1 244 ? 59.751 -24.088 11.581 1.00 35.20  ?  936  PRO   A CA   1 
ATOM   3865 C  C    . PRO   A 1 244 ? 60.550 -24.355 10.304 1.00 42.86  ?  936  PRO   A C    1 
ATOM   3866 O  O    . PRO   A 1 244 ? 61.766 -24.551 10.407 1.00 44.58  ?  936  PRO   A O    1 
ATOM   3867 C  CB   . PRO   A 1 244 ? 60.095 -22.703 12.119 1.00 24.58  ?  936  PRO   A CB   1 
ATOM   3868 C  CG   . PRO   A 1 244 ? 60.253 -22.887 13.625 1.00 32.00  ?  936  PRO   A CG   1 
ATOM   3869 C  CD   . PRO   A 1 244 ? 60.601 -24.359 13.847 1.00 27.57  ?  936  PRO   A CD   1 
ATOM   3870 H  HA   . PRO   A 1 244 ? 58.671 -24.183 11.472 1.00 37.20  ?  936  PRO   A HA   1 
ATOM   3871 H  HB2  . PRO   A 1 244 ? 61.031 -22.324 11.707 1.00 26.58  ?  936  PRO   A HB2  1 
ATOM   3872 H  HB3  . PRO   A 1 244 ? 59.332 -21.963 11.885 1.00 26.58  ?  936  PRO   A HB3  1 
ATOM   3873 H  HG2  . PRO   A 1 244 ? 60.974 -22.208 14.071 1.00 34.00  ?  936  PRO   A HG2  1 
ATOM   3874 H  HG3  . PRO   A 1 244 ? 59.295 -22.684 14.106 1.00 34.00  ?  936  PRO   A HG3  1 
ATOM   3875 H  HD2  . PRO   A 1 244 ? 61.681 -24.481 13.940 1.00 29.57  ?  936  PRO   A HD2  1 
ATOM   3876 H  HD3  . PRO   A 1 244 ? 60.145 -24.723 14.766 1.00 29.57  ?  936  PRO   A HD3  1 
ATOM   3877 N  N    . PRO   A 1 245 ? 59.926 -24.330 9.120  1.00 41.07  ?  937  PRO   A N    1 
ATOM   3878 C  CA   . PRO   A 1 245 ? 60.602 -24.507 7.838  1.00 35.53  ?  937  PRO   A CA   1 
ATOM   3879 C  C    . PRO   A 1 245 ? 61.922 -23.791 7.603  1.00 36.61  ?  937  PRO   A C    1 
ATOM   3880 O  O    . PRO   A 1 245 ? 62.829 -24.370 7.012  1.00 40.44  ?  937  PRO   A O    1 
ATOM   3881 C  CB   . PRO   A 1 245 ? 59.582 -24.104 6.798  1.00 32.77  ?  937  PRO   A CB   1 
ATOM   3882 C  CG   . PRO   A 1 245 ? 58.228 -24.335 7.469  1.00 39.31  ?  937  PRO   A CG   1 
ATOM   3883 C  CD   . PRO   A 1 245 ? 58.477 -24.199 8.971  1.00 44.33  ?  937  PRO   A CD   1 
ATOM   3884 H  HA   . PRO   A 1 245 ? 60.794 -25.578 7.747  1.00 37.53  ?  937  PRO   A HA   1 
ATOM   3885 H  HB2  . PRO   A 1 245 ? 59.676 -23.046 6.544  1.00 34.77  ?  937  PRO   A HB2  1 
ATOM   3886 H  HB3  . PRO   A 1 245 ? 59.689 -24.673 5.873  1.00 34.77  ?  937  PRO   A HB3  1 
ATOM   3887 H  HG2  . PRO   A 1 245 ? 57.460 -23.649 7.109  1.00 41.31  ?  937  PRO   A HG2  1 
ATOM   3888 H  HG3  . PRO   A 1 245 ? 57.886 -25.349 7.252  1.00 41.31  ?  937  PRO   A HG3  1 
ATOM   3889 H  HD2  . PRO   A 1 245 ? 58.112 -23.239 9.335  1.00 46.33  ?  937  PRO   A HD2  1 
ATOM   3890 H  HD3  . PRO   A 1 245 ? 57.945 -24.987 9.508  1.00 46.33  ?  937  PRO   A HD3  1 
ATOM   3891 N  N    . ILE   A 1 246 ? 62.042 -22.552 8.075  1.00 31.67  ?  938  ILE   A N    1 
ATOM   3892 C  CA   . ILE   A 1 246 ? 63.295 -21.826 7.889  1.00 22.09  ?  938  ILE   A CA   1 
ATOM   3893 C  C    . ILE   A 1 246 ? 64.405 -22.248 8.851  1.00 24.55  ?  938  ILE   A C    1 
ATOM   3894 O  O    . ILE   A 1 246 ? 65.535 -21.800 8.685  1.00 27.86  ?  938  ILE   A O    1 
ATOM   3895 C  CB   . ILE   A 1 246 ? 63.063 -20.305 8.007  1.00 32.80  ?  938  ILE   A CB   1 
ATOM   3896 C  CG1  . ILE   A 1 246 ? 62.773 -19.798 9.429  1.00 24.80  ?  938  ILE   A CG1  1 
ATOM   3897 C  CG2  . ILE   A 1 246 ? 62.016 -19.840 6.993  1.00 20.89  ?  938  ILE   A CG2  1 
ATOM   3898 C  CD1  . ILE   A 1 246 ? 62.770 -18.291 9.566  1.00 20.55  ?  938  ILE   A CD1  1 
ATOM   3899 H  H    . ILE   A 1 246 ? 61.243 -22.063 8.469  1.00 33.67  ?  938  ILE   A H    1 
ATOM   3900 H  HA   . ILE   A 1 246 ? 63.670 -22.020 6.882  1.00 24.09  ?  938  ILE   A HA   1 
ATOM   3901 H  HB   . ILE   A 1 246 ? 64.001 -19.835 7.703  1.00 34.80  ?  938  ILE   A HB   1 
ATOM   3902 H  HG12 . ILE   A 1 246 ? 61.837 -20.204 9.799  1.00 26.80  ?  938  ILE   A HG12 1 
ATOM   3903 H  HG13 . ILE   A 1 246 ? 63.525 -20.157 10.127 1.00 26.80  ?  938  ILE   A HG13 1 
ATOM   3904 H  HG21 . ILE   A 1 246 ? 61.912 -18.759 6.982  1.00 22.89  ?  938  ILE   A HG21 1 
ATOM   3905 H  HG22 . ILE   A 1 246 ? 62.288 -20.145 5.982  1.00 22.89  ?  938  ILE   A HG22 1 
ATOM   3906 H  HG23 . ILE   A 1 246 ? 61.028 -20.247 7.200  1.00 22.89  ?  938  ILE   A HG23 1 
ATOM   3907 H  HD11 . ILE   A 1 246 ? 62.715 -18.008 10.616 1.00 22.55  ?  938  ILE   A HD11 1 
ATOM   3908 H  HD12 . ILE   A 1 246 ? 63.681 -17.860 9.161  1.00 22.55  ?  938  ILE   A HD12 1 
ATOM   3909 H  HD13 . ILE   A 1 246 ? 61.915 -17.835 9.068  1.00 22.55  ?  938  ILE   A HD13 1 
ATOM   3910 N  N    . CYS   A 1 247 ? 64.098 -23.033 9.882  1.00 22.27  ?  939  CYS   A N    1 
ATOM   3911 C  CA   . CYS   A 1 247 ? 65.078 -23.282 10.926 1.00 25.04  ?  939  CYS   A CA   1 
ATOM   3912 C  C    . CYS   A 1 247 ? 65.908 -24.504 10.637 1.00 32.51  ?  939  CYS   A C    1 
ATOM   3913 O  O    . CYS   A 1 247 ? 65.412 -25.633 10.581 1.00 32.33  ?  939  CYS   A O    1 
ATOM   3914 C  CB   . CYS   A 1 247 ? 64.418 -23.508 12.284 1.00 32.22  ?  939  CYS   A CB   1 
ATOM   3915 S  SG   . CYS   A 1 247 ? 63.629 -22.033 12.952 1.00 38.56  ?  939  CYS   A SG   1 
ATOM   3916 H  H    . CYS   A 1 247 ? 63.210 -23.529 9.910  1.00 24.27  ?  939  CYS   A H    1 
ATOM   3917 H  HA   . CYS   A 1 247 ? 65.736 -22.420 11.047 1.00 27.04  ?  939  CYS   A HA   1 
ATOM   3918 H  HB2  . CYS   A 1 247 ? 63.674 -24.304 12.224 1.00 34.22  ?  939  CYS   A HB2  1 
ATOM   3919 H  HB3  . CYS   A 1 247 ? 65.154 -23.836 13.020 1.00 34.22  ?  939  CYS   A HB3  1 
ATOM   3920 H  HG   . CYS   A 1 247 ? 62.882 -21.794 11.870 1.00 40.56  ?  939  CYS   A HG   1 
ATOM   3921 N  N    . THR   A 1 248 ? 67.211 -24.273 10.599 1.00 27.11  ?  940  THR   A N    1 
ATOM   3922 C  CA   . THR   A 1 248 ? 68.158 -25.359 10.803 1.00 27.08  ?  940  THR   A CA   1 
ATOM   3923 C  C    . THR   A 1 248 ? 67.954 -26.076 12.138 1.00 28.18  ?  940  THR   A C    1 
ATOM   3924 O  O    . THR   A 1 248 ? 67.365 -25.524 13.080 1.00 28.57  ?  940  THR   A O    1 
ATOM   3925 C  CB   . THR   A 1 248 ? 69.590 -24.829 10.662 1.00 39.40  ?  940  THR   A CB   1 
ATOM   3926 O  OG1  . THR   A 1 248 ? 69.919 -23.880 11.669 1.00 29.48  ?  940  THR   A OG1  1 
ATOM   3927 C  CG2  . THR   A 1 248 ? 69.882 -24.280 9.270  1.00 21.80  ?  940  THR   A CG2  1 
ATOM   3928 H  H    . THR   A 1 248 ? 67.555 -23.325 10.660 1.00 29.11  ?  940  THR   A H    1 
ATOM   3929 H  HA   . THR   A 1 248 ? 67.984 -26.093 10.013 1.00 29.08  ?  940  THR   A HA   1 
ATOM   3930 H  HB   . THR   A 1 248 ? 70.286 -25.648 10.838 1.00 41.40  ?  940  THR   A HB   1 
ATOM   3931 H  HG1  . THR   A 1 248 ? 69.507 -23.045 11.443 1.00 31.48  ?  940  THR   A HG1  1 
ATOM   3932 H  HG21 . THR   A 1 248 ? 70.920 -23.972 9.179  1.00 23.80  ?  940  THR   A HG21 1 
ATOM   3933 H  HG22 . THR   A 1 248 ? 69.707 -25.045 8.513  1.00 23.80  ?  940  THR   A HG22 1 
ATOM   3934 H  HG23 . THR   A 1 248 ? 69.256 -23.426 9.014  1.00 23.80  ?  940  THR   A HG23 1 
ATOM   3935 N  N    . ILE   A 1 249 ? 68.480 -27.295 12.235 1.00 27.55  ?  941  ILE   A N    1 
ATOM   3936 C  CA   . ILE   A 1 249 ? 68.459 -28.020 13.503 1.00 33.30  ?  941  ILE   A CA   1 
ATOM   3937 C  C    . ILE   A 1 249 ? 69.191 -27.280 14.625 1.00 32.54  ?  941  ILE   A C    1 
ATOM   3938 O  O    . ILE   A 1 249 ? 68.823 -27.406 15.789 1.00 32.95  ?  941  ILE   A O    1 
ATOM   3939 C  CB   . ILE   A 1 249 ? 68.939 -29.478 13.331 1.00 39.77  ?  941  ILE   A CB   1 
ATOM   3940 C  CG1  . ILE   A 1 249 ? 68.884 -30.298 14.624 1.00 27.30  ?  941  ILE   A CG1  1 
ATOM   3941 C  CG2  . ILE   A 1 249 ? 70.300 -29.564 12.639 1.00 29.75  ?  941  ILE   A CG2  1 
ATOM   3942 C  CD1  . ILE   A 1 249 ? 69.015 -31.802 14.430 1.00 39.85  ?  941  ILE   A CD1  1 
ATOM   3943 H  H    . ILE   A 1 249 ? 68.936 -27.718 11.433 1.00 29.55  ?  941  ILE   A H    1 
ATOM   3944 H  HA   . ILE   A 1 249 ? 67.413 -28.076 13.812 1.00 35.30  ?  941  ILE   A HA   1 
ATOM   3945 H  HB   . ILE   A 1 249 ? 68.223 -29.951 12.663 1.00 41.77  ?  941  ILE   A HB   1 
ATOM   3946 H  HG12 . ILE   A 1 249 ? 69.664 -29.971 15.312 1.00 29.30  ?  941  ILE   A HG12 1 
ATOM   3947 H  HG13 . ILE   A 1 249 ? 67.937 -30.104 15.130 1.00 29.30  ?  941  ILE   A HG13 1 
ATOM   3948 H  HG21 . ILE   A 1 249 ? 70.686 -30.581 12.598 1.00 31.75  ?  941  ILE   A HG21 1 
ATOM   3949 H  HG22 . ILE   A 1 249 ? 70.223 -29.234 11.605 1.00 31.75  ?  941  ILE   A HG22 1 
ATOM   3950 H  HG23 . ILE   A 1 249 ? 71.054 -28.949 13.122 1.00 31.75  ?  941  ILE   A HG23 1 
ATOM   3951 H  HD11 . ILE   A 1 249 ? 68.867 -32.325 15.375 1.00 41.85  ?  941  ILE   A HD11 1 
ATOM   3952 H  HD12 . ILE   A 1 249 ? 68.269 -32.179 13.728 1.00 41.85  ?  941  ILE   A HD12 1 
ATOM   3953 H  HD13 . ILE   A 1 249 ? 69.999 -32.089 14.060 1.00 41.85  ?  941  ILE   A HD13 1 
ATOM   3954 N  N    . ASP   A 1 250 ? 70.166 -26.451 14.262 1.00 28.28  ?  942  ASP   A N    1 
ATOM   3955 C  CA   . ASP   A 1 250 ? 70.881 -25.592 15.210 1.00 27.63  ?  942  ASP   A CA   1 
ATOM   3956 C  C    . ASP   A 1 250 ? 69.983 -24.653 15.984 1.00 34.86  ?  942  ASP   A C    1 
ATOM   3957 O  O    . ASP   A 1 250 ? 70.036 -24.592 17.217 1.00 33.53  ?  942  ASP   A O    1 
ATOM   3958 C  CB   . ASP   A 1 250 ? 71.946 -24.754 14.505 1.00 26.53  ?  942  ASP   A CB   1 
ATOM   3959 C  CG   . ASP   A 1 250 ? 73.026 -25.636 13.936 1.00 41.05  ?  942  ASP   A CG   1 
ATOM   3960 O  OD1  . ASP   A 1 250 ? 72.858 -26.151 12.809 1.00 31.71  ?  942  ASP   A OD1  1 
ATOM   3961 O  OD2  . ASP   A 1 250 ? 74.049 -25.840 14.612 1.00 41.89  -1 942  ASP   A OD2  1 
ATOM   3962 H  H    . ASP   A 1 250 ? 70.396 -26.371 13.282 1.00 30.28  ?  942  ASP   A H    1 
ATOM   3963 H  HA   . ASP   A 1 250 ? 71.370 -26.240 15.941 1.00 29.63  ?  942  ASP   A HA   1 
ATOM   3964 H  HB2  . ASP   A 1 250 ? 71.500 -24.168 13.705 1.00 28.53  ?  942  ASP   A HB2  1 
ATOM   3965 H  HB3  . ASP   A 1 250 ? 72.409 -24.044 15.195 1.00 28.53  ?  942  ASP   A HB3  1 
ATOM   3966 N  N    . VAL   A 1 251 ? 69.132 -23.954 15.241 1.00 26.00  ?  943  VAL   A N    1 
ATOM   3967 C  CA   . VAL   A 1 251 ? 68.215 -23.024 15.874 1.00 31.27  ?  943  VAL   A CA   1 
ATOM   3968 C  C    . VAL   A 1 251 ? 67.110 -23.782 16.595 1.00 34.43  ?  943  VAL   A C    1 
ATOM   3969 O  O    . VAL   A 1 251 ? 66.754 -23.447 17.726 1.00 36.22  ?  943  VAL   A O    1 
ATOM   3970 C  CB   . VAL   A 1 251 ? 67.648 -22.054 14.829 1.00 29.87  ?  943  VAL   A CB   1 
ATOM   3971 C  CG1  . VAL   A 1 251 ? 66.563 -21.125 15.369 1.00 23.24  ?  943  VAL   A CG1  1 
ATOM   3972 C  CG2  . VAL   A 1 251 ? 68.760 -21.215 14.215 1.00 18.10  ?  943  VAL   A CG2  1 
ATOM   3973 H  H    . VAL   A 1 251 ? 69.126 -24.077 14.237 1.00 28.00  ?  943  VAL   A H    1 
ATOM   3974 H  HA   . VAL   A 1 251 ? 68.752 -22.436 16.623 1.00 33.27  ?  943  VAL   A HA   1 
ATOM   3975 H  HB   . VAL   A 1 251 ? 67.198 -22.642 14.027 1.00 31.87  ?  943  VAL   A HB   1 
ATOM   3976 H  HG11 . VAL   A 1 251 ? 65.716 -21.676 15.764 1.00 25.24  ?  943  VAL   A HG11 1 
ATOM   3977 H  HG12 . VAL   A 1 251 ? 66.942 -20.485 16.166 1.00 25.24  ?  943  VAL   A HG12 1 
ATOM   3978 H  HG13 . VAL   A 1 251 ? 66.166 -20.484 14.583 1.00 25.24  ?  943  VAL   A HG13 1 
ATOM   3979 H  HG21 . VAL   A 1 251 ? 68.382 -20.583 13.412 1.00 20.10  ?  943  VAL   A HG21 1 
ATOM   3980 H  HG22 . VAL   A 1 251 ? 69.210 -20.557 14.957 1.00 20.10  ?  943  VAL   A HG22 1 
ATOM   3981 H  HG23 . VAL   A 1 251 ? 69.553 -21.829 13.789 1.00 20.10  ?  943  VAL   A HG23 1 
ATOM   3982 N  N    . TYR   A 1 252 ? 66.587 -24.819 15.944 1.00 28.63  ?  944  TYR   A N    1 
ATOM   3983 C  CA   . TYR   A 1 252 ? 65.479 -25.555 16.529 1.00 30.97  ?  944  TYR   A CA   1 
ATOM   3984 C  C    . TYR   A 1 252 ? 65.834 -26.307 17.806 1.00 37.48  ?  944  TYR   A C    1 
ATOM   3985 O  O    . TYR   A 1 252 ? 65.058 -26.313 18.759 1.00 39.68  ?  944  TYR   A O    1 
ATOM   3986 C  CB   . TYR   A 1 252 ? 64.892 -26.508 15.514 1.00 28.33  ?  944  TYR   A CB   1 
ATOM   3987 C  CG   . TYR   A 1 252 ? 63.660 -27.271 15.978 1.00 41.10  ?  944  TYR   A CG   1 
ATOM   3988 C  CD1  . TYR   A 1 252 ? 62.534 -26.573 16.476 1.00 35.44  ?  944  TYR   A CD1  1 
ATOM   3989 C  CD2  . TYR   A 1 252 ? 63.640 -28.677 15.911 1.00 34.58  ?  944  TYR   A CD2  1 
ATOM   3990 C  CE1  . TYR   A 1 252 ? 61.392 -27.287 16.893 1.00 36.21  ?  944  TYR   A CE1  1 
ATOM   3991 C  CE2  . TYR   A 1 252 ? 62.499 -29.387 16.325 1.00 36.59  ?  944  TYR   A CE2  1 
ATOM   3992 C  CZ   . TYR   A 1 252 ? 61.373 -28.694 16.808 1.00 40.31  ?  944  TYR   A CZ   1 
ATOM   3993 O  OH   . TYR   A 1 252 ? 60.267 -29.387 17.184 1.00 40.73  ?  944  TYR   A OH   1 
ATOM   3994 H  H    . TYR   A 1 252 ? 66.951 -25.080 15.033 1.00 30.63  ?  944  TYR   A H    1 
ATOM   3995 H  HA   . TYR   A 1 252 ? 64.710 -24.827 16.792 1.00 32.97  ?  944  TYR   A HA   1 
ATOM   3996 H  HB2  . TYR   A 1 252 ? 64.616 -25.951 14.618 1.00 30.33  ?  944  TYR   A HB2  1 
ATOM   3997 H  HB3  . TYR   A 1 252 ? 65.654 -27.221 15.194 1.00 30.33  ?  944  TYR   A HB3  1 
ATOM   3998 H  HD1  . TYR   A 1 252 ? 62.543 -25.495 16.533 1.00 37.44  ?  944  TYR   A HD1  1 
ATOM   3999 H  HD2  . TYR   A 1 252 ? 64.498 -29.212 15.533 1.00 36.58  ?  944  TYR   A HD2  1 
ATOM   4000 H  HE1  . TYR   A 1 252 ? 60.528 -26.754 17.265 1.00 38.21  ?  944  TYR   A HE1  1 
ATOM   4001 H  HE2  . TYR   A 1 252 ? 62.482 -30.465 16.265 1.00 38.59  ?  944  TYR   A HE2  1 
ATOM   4002 H  HH   . TYR   A 1 252 ? 59.548 -28.828 17.488 1.00 42.73  ?  944  TYR   A HH   1 
ATOM   4003 N  N    . MET   A 1 253 ? 67.036 -26.868 17.860 1.00 32.59  ?  945  MET   A N    1 
ATOM   4004 C  CA   . MET   A 1 253 ? 67.527 -27.515 19.064 1.00 29.36  ?  945  MET   A CA   1 
ATOM   4005 C  C    . MET   A 1 253 ? 67.607 -26.560 20.261 1.00 37.54  ?  945  MET   A C    1 
ATOM   4006 O  O    . MET   A 1 253 ? 67.354 -26.961 21.398 1.00 36.55  ?  945  MET   A O    1 
ATOM   4007 C  CB   . MET   A 1 253 ? 68.883 -28.159 18.765 1.00 28.75  ?  945  MET   A CB   1 
ATOM   4008 C  CG   . MET   A 1 253 ? 69.471 -29.052 19.857 1.00 42.63  ?  945  MET   A CG   1 
ATOM   4009 S  SD   . MET   A 1 253 ? 68.640 -30.644 19.982 1.00 69.39  ?  945  MET   A SD   1 
ATOM   4010 C  CE   . MET   A 1 253 ? 69.470 -31.546 18.677 1.00 39.47  ?  945  MET   A CE   1 
ATOM   4011 H  H    . MET   A 1 253 ? 67.648 -26.850 17.047 1.00 34.59  ?  945  MET   A H    1 
ATOM   4012 H  HA   . MET   A 1 253 ? 66.825 -28.312 19.317 1.00 31.36  ?  945  MET   A HA   1 
ATOM   4013 H  HB2  . MET   A 1 253 ? 68.804 -28.760 17.861 1.00 30.75  ?  945  MET   A HB2  1 
ATOM   4014 H  HB3  . MET   A 1 253 ? 69.604 -27.372 18.536 1.00 30.75  ?  945  MET   A HB3  1 
ATOM   4015 H  HG2  . MET   A 1 253 ? 70.527 -29.236 19.654 1.00 44.63  ?  945  MET   A HG2  1 
ATOM   4016 H  HG3  . MET   A 1 253 ? 69.437 -28.561 20.829 1.00 44.63  ?  945  MET   A HG3  1 
ATOM   4017 H  HE1  . MET   A 1 253 ? 68.979 -32.508 18.523 1.00 41.47  ?  945  MET   A HE1  1 
ATOM   4018 H  HE2  . MET   A 1 253 ? 69.464 -31.001 17.734 1.00 41.47  ?  945  MET   A HE2  1 
ATOM   4019 H  HE3  . MET   A 1 253 ? 70.496 -31.744 18.975 1.00 41.47  ?  945  MET   A HE3  1 
ATOM   4020 N  N    . ILE   A 1 254 ? 67.913 -25.289 20.007 1.00 33.08  ?  946  ILE   A N    1 
ATOM   4021 C  CA   . ILE   A 1 254 ? 67.888 -24.284 21.068 1.00 42.52  ?  946  ILE   A CA   1 
ATOM   4022 C  C    . ILE   A 1 254 ? 66.471 -24.039 21.581 1.00 34.78  ?  946  ILE   A C    1 
ATOM   4023 O  O    . ILE   A 1 254 ? 66.265 -23.974 22.796 1.00 26.12  ?  946  ILE   A O    1 
ATOM   4024 C  CB   . ILE   A 1 254 ? 68.601 -22.983 20.632 1.00 48.16  ?  946  ILE   A CB   1 
ATOM   4025 C  CG1  . ILE   A 1 254 ? 70.097 -23.238 20.411 1.00 47.53  ?  946  ILE   A CG1  1 
ATOM   4026 C  CG2  . ILE   A 1 254 ? 68.418 -21.822 21.611 1.00 43.35  ?  946  ILE   A CG2  1 
ATOM   4027 C  CD1  . ILE   A 1 254 ? 70.809 -22.149 19.619 1.00 45.53  ?  946  ILE   A CD1  1 
ATOM   4028 H  H    . ILE   A 1 254 ? 68.083 -24.992 19.054 1.00 35.08  ?  946  ILE   A H    1 
ATOM   4029 H  HA   . ILE   A 1 254 ? 68.451 -24.680 21.917 1.00 44.52  ?  946  ILE   A HA   1 
ATOM   4030 H  HB   . ILE   A 1 254 ? 68.172 -22.667 19.682 1.00 50.16  ?  946  ILE   A HB   1 
ATOM   4031 H  HG12 . ILE   A 1 254 ? 70.598 -23.385 21.369 1.00 49.53  ?  946  ILE   A HG12 1 
ATOM   4032 H  HG13 . ILE   A 1 254 ? 70.241 -24.171 19.867 1.00 49.53  ?  946  ILE   A HG13 1 
ATOM   4033 H  HG21 . ILE   A 1 254 ? 68.985 -20.943 21.311 1.00 45.35  ?  946  ILE   A HG21 1 
ATOM   4034 H  HG22 . ILE   A 1 254 ? 67.380 -21.495 21.677 1.00 45.35  ?  946  ILE   A HG22 1 
ATOM   4035 H  HG23 . ILE   A 1 254 ? 68.746 -22.097 22.614 1.00 45.35  ?  946  ILE   A HG23 1 
ATOM   4036 H  HD11 . ILE   A 1 254 ? 71.845 -22.436 19.429 1.00 47.53  ?  946  ILE   A HD11 1 
ATOM   4037 H  HD12 . ILE   A 1 254 ? 70.335 -22.002 18.650 1.00 47.53  ?  946  ILE   A HD12 1 
ATOM   4038 H  HD13 . ILE   A 1 254 ? 70.833 -21.195 20.143 1.00 47.53  ?  946  ILE   A HD13 1 
ATOM   4039 N  N    . MET   A 1 255 ? 65.498 -23.976 20.670 1.00 27.49  ?  947  MET   A N    1 
ATOM   4040 C  CA   . MET   A 1 255 ? 64.093 -23.905 21.078 1.00 29.10  ?  947  MET   A CA   1 
ATOM   4041 C  C    . MET   A 1 255 ? 63.662 -25.095 21.922 1.00 38.64  ?  947  MET   A C    1 
ATOM   4042 O  O    . MET   A 1 255 ? 63.146 -24.937 23.027 1.00 47.88  ?  947  MET   A O    1 
ATOM   4043 C  CB   . MET   A 1 255 ? 63.130 -23.776 19.904 1.00 31.68  ?  947  MET   A CB   1 
ATOM   4044 C  CG   . MET   A 1 255 ? 63.429 -22.664 18.914 1.00 29.69  ?  947  MET   A CG   1 
ATOM   4045 S  SD   . MET   A 1 255 ? 62.173 -22.693 17.626 1.00 45.87  ?  947  MET   A SD   1 
ATOM   4046 C  CE   . MET   A 1 255 ? 63.072 -21.891 16.337 1.00 38.89  ?  947  MET   A CE   1 
ATOM   4047 H  H    . MET   A 1 255 ? 65.736 -24.103 19.694 1.00 29.49  ?  947  MET   A H    1 
ATOM   4048 H  HA   . MET   A 1 255 ? 63.980 -23.010 21.695 1.00 31.10  ?  947  MET   A HA   1 
ATOM   4049 H  HB2  . MET   A 1 255 ? 63.077 -24.717 19.355 1.00 33.68  ?  947  MET   A HB2  1 
ATOM   4050 H  HB3  . MET   A 1 255 ? 62.126 -23.618 20.303 1.00 33.68  ?  947  MET   A HB3  1 
ATOM   4051 H  HG2  . MET   A 1 255 ? 63.438 -21.687 19.400 1.00 31.69  ?  947  MET   A HG2  1 
ATOM   4052 H  HG3  . MET   A 1 255 ? 64.407 -22.815 18.462 1.00 31.69  ?  947  MET   A HG3  1 
ATOM   4053 H  HE1  . MET   A 1 255 ? 62.370 -21.419 15.655 1.00 40.89  ?  947  MET   A HE1  1 
ATOM   4054 H  HE2  . MET   A 1 255 ? 63.750 -21.135 16.725 1.00 40.89  ?  947  MET   A HE2  1 
ATOM   4055 H  HE3  . MET   A 1 255 ? 63.653 -22.632 15.789 1.00 40.89  ?  947  MET   A HE3  1 
ATOM   4056 N  N    . VAL   A 1 256 ? 63.954 -26.286 21.417 1.00 41.51  ?  948  VAL   A N    1 
ATOM   4057 C  CA   . VAL   A 1 256 ? 63.700 -27.540 22.116 1.00 34.75  ?  948  VAL   A CA   1 
ATOM   4058 C  C    . VAL   A 1 256 ? 64.319 -27.610 23.510 1.00 32.72  ?  948  VAL   A C    1 
ATOM   4059 O  O    . VAL   A 1 256 ? 63.652 -28.004 24.467 1.00 26.67  ?  948  VAL   A O    1 
ATOM   4060 C  CB   . VAL   A 1 256 ? 64.093 -28.714 21.205 1.00 42.45  ?  948  VAL   A CB   1 
ATOM   4061 C  CG1  . VAL   A 1 256 ? 64.133 -30.072 21.887 1.00 29.17  ?  948  VAL   A CG1  1 
ATOM   4062 C  CG2  . VAL   A 1 256 ? 63.170 -28.779 19.995 1.00 32.64  ?  948  VAL   A CG2  1 
ATOM   4063 H  H    . VAL   A 1 256 ? 64.387 -26.327 20.496 1.00 43.51  ?  948  VAL   A H    1 
ATOM   4064 H  HA   . VAL   A 1 256 ? 62.623 -27.593 22.279 1.00 36.75  ?  948  VAL   A HA   1 
ATOM   4065 H  HB   . VAL   A 1 256 ? 65.103 -28.527 20.840 1.00 44.45  ?  948  VAL   A HB   1 
ATOM   4066 H  HG11 . VAL   A 1 256 ? 64.390 -30.850 21.170 1.00 31.17  ?  948  VAL   A HG11 1 
ATOM   4067 H  HG12 . VAL   A 1 256 ? 64.878 -30.127 22.681 1.00 31.17  ?  948  VAL   A HG12 1 
ATOM   4068 H  HG13 . VAL   A 1 256 ? 63.156 -30.315 22.301 1.00 31.17  ?  948  VAL   A HG13 1 
ATOM   4069 H  HG21 . VAL   A 1 256 ? 63.482 -29.557 19.299 1.00 34.64  ?  948  VAL   A HG21 1 
ATOM   4070 H  HG22 . VAL   A 1 256 ? 62.142 -28.975 20.298 1.00 34.64  ?  948  VAL   A HG22 1 
ATOM   4071 H  HG23 . VAL   A 1 256 ? 63.152 -27.849 19.430 1.00 34.64  ?  948  VAL   A HG23 1 
ATOM   4072 N  N    . LYS   A 1 257 ? 65.563 -27.157 23.636 1.00 32.42  ?  949  LYS   A N    1 
ATOM   4073 C  CA   . LYS   A 1 257 ? 66.203 -27.036 24.941 1.00 27.20  ?  949  LYS   A CA   1 
ATOM   4074 C  C    . LYS   A 1 257 ? 65.495 -26.077 25.909 1.00 44.14  ?  949  LYS   A C    1 
ATOM   4075 O  O    . LYS   A 1 257 ? 65.512 -26.298 27.121 1.00 39.68  ?  949  LYS   A O    1 
ATOM   4076 C  CB   . LYS   A 1 257 ? 67.652 -26.601 24.783 1.00 28.17  ?  949  LYS   A CB   1 
ATOM   4077 C  CG   . LYS   A 1 257 ? 68.636 -27.696 24.415 1.00 41.45  ?  949  LYS   A CG   1 
ATOM   4078 C  CD   . LYS   A 1 257 ? 70.002 -27.110 24.080 1.00 48.97  ?  949  LYS   A CD   1 
ATOM   4079 C  CE   . LYS   A 1 257 ? 71.078 -28.152 23.818 1.00 56.85  ?  949  LYS   A CE   1 
ATOM   4080 N  NZ   . LYS   A 1 257 ? 72.316 -27.521 23.326 1.00 51.33  1  949  LYS   A NZ   1 
ATOM   4081 H  H    . LYS   A 1 257 ? 66.077 -26.880 22.803 1.00 34.42  ?  949  LYS   A H    1 
ATOM   4082 H  HA   . LYS   A 1 257 ? 66.199 -28.024 25.404 1.00 29.20  ?  949  LYS   A HA   1 
ATOM   4083 H  HB2  . LYS   A 1 257 ? 67.707 -25.785 24.062 1.00 30.17  ?  949  LYS   A HB2  1 
ATOM   4084 H  HB3  . LYS   A 1 257 ? 68.017 -26.187 25.717 1.00 30.17  ?  949  LYS   A HB3  1 
ATOM   4085 H  HG2  . LYS   A 1 257 ? 68.717 -28.395 25.248 1.00 43.45  ?  949  LYS   A HG2  1 
ATOM   4086 H  HG3  . LYS   A 1 257 ? 68.260 -28.263 23.561 1.00 43.45  ?  949  LYS   A HG3  1 
ATOM   4087 H  HD2  . LYS   A 1 257 ? 69.900 -26.467 23.203 1.00 50.97  ?  949  LYS   A HD2  1 
ATOM   4088 H  HD3  . LYS   A 1 257 ? 70.331 -26.462 24.894 1.00 50.97  ?  949  LYS   A HD3  1 
ATOM   4089 H  HE2  . LYS   A 1 257 ? 71.300 -28.699 24.735 1.00 58.85  ?  949  LYS   A HE2  1 
ATOM   4090 H  HE3  . LYS   A 1 257 ? 70.743 -28.885 23.082 1.00 58.85  ?  949  LYS   A HE3  1 
ATOM   4091 H  HZ1  . LYS   A 1 257 ? 72.514 -26.684 23.867 1.00 53.33  ?  949  LYS   A HZ1  1 
ATOM   4092 H  HZ2  . LYS   A 1 257 ? 73.088 -28.166 23.404 1.00 53.33  ?  949  LYS   A HZ2  1 
ATOM   4093 H  HZ3  . LYS   A 1 257 ? 72.199 -27.257 22.358 1.00 53.33  ?  949  LYS   A HZ3  1 
ATOM   4094 N  N    . CYS   A 1 258 ? 64.840 -25.035 25.395 1.00 37.84  ?  950  CYS   A N    1 
ATOM   4095 C  CA   . CYS   A 1 258 ? 64.013 -24.164 26.241 1.00 43.51  ?  950  CYS   A CA   1 
ATOM   4096 C  C    . CYS   A 1 258 ? 62.733 -24.825 26.736 1.00 41.63  ?  950  CYS   A C    1 
ATOM   4097 O  O    . CYS   A 1 258 ? 62.091 -24.318 27.654 1.00 42.82  ?  950  CYS   A O    1 
ATOM   4098 C  CB   . CYS   A 1 258 ? 63.632 -22.850 25.547 1.00 31.24  ?  950  CYS   A CB   1 
ATOM   4099 S  SG   . CYS   A 1 258 ? 64.994 -21.792 24.986 1.00 34.59  ?  950  CYS   A SG   1 
ATOM   4100 H  H    . CYS   A 1 258 ? 64.806 -24.910 24.388 1.00 39.84  ?  950  CYS   A H    1 
ATOM   4101 H  HA   . CYS   A 1 258 ? 64.583 -23.900 27.131 1.00 45.51  ?  950  CYS   A HA   1 
ATOM   4102 H  HB2  . CYS   A 1 258 ? 62.996 -23.053 24.686 1.00 33.24  ?  950  CYS   A HB2  1 
ATOM   4103 H  HB3  . CYS   A 1 258 ? 63.019 -22.252 26.217 1.00 33.24  ?  950  CYS   A HB3  1 
ATOM   4104 H  HG   . CYS   A 1 258 ? 65.533 -22.690 24.144 1.00 36.59  ?  950  CYS   A HG   1 
ATOM   4105 N  N    . TRP   A 1 259 ? 62.383 -25.963 26.155 1.00 35.77  ?  951  TRP   A N    1 
ATOM   4106 C  CA   . TRP   A 1 259 ? 61.139 -26.640 26.468 1.00 24.36  ?  951  TRP   A CA   1 
ATOM   4107 C  C    . TRP   A 1 259 ? 61.376 -27.955 27.192 1.00 27.83  ?  951  TRP   A C    1 
ATOM   4108 O  O    . TRP   A 1 259 ? 60.496 -28.814 27.251 1.00 37.17  ?  951  TRP   A O    1 
ATOM   4109 C  CB   . TRP   A 1 259 ? 60.311 -26.837 25.217 1.00 28.64  ?  951  TRP   A CB   1 
ATOM   4110 C  CG   . TRP   A 1 259 ? 60.003 -25.635 24.368 1.00 39.50  ?  951  TRP   A CG   1 
ATOM   4111 C  CD1  . TRP   A 1 259 ? 59.783 -24.386 24.830 1.00 28.40  ?  951  TRP   A CD1  1 
ATOM   4112 C  CD2  . TRP   A 1 259 ? 59.863 -25.552 22.915 1.00 39.67  ?  951  TRP   A CD2  1 
ATOM   4113 N  NE1  . TRP   A 1 259 ? 59.503 -23.542 23.777 1.00 34.01  ?  951  TRP   A NE1  1 
ATOM   4114 C  CE2  . TRP   A 1 259 ? 59.541 -24.201 22.568 1.00 33.98  ?  951  TRP   A CE2  1 
ATOM   4115 C  CE3  . TRP   A 1 259 ? 59.971 -26.478 21.843 1.00 35.23  ?  951  TRP   A CE3  1 
ATOM   4116 C  CZ2  . TRP   A 1 259 ? 59.336 -23.791 21.245 1.00 27.62  ?  951  TRP   A CZ2  1 
ATOM   4117 C  CZ3  . TRP   A 1 259 ? 59.767 -26.067 20.503 1.00 25.18  ?  951  TRP   A CZ3  1 
ATOM   4118 C  CH2  . TRP   A 1 259 ? 59.452 -24.726 20.207 1.00 35.73  ?  951  TRP   A CH2  1 
ATOM   4119 H  H    . TRP   A 1 259 ? 62.949 -26.341 25.402 1.00 37.77  ?  951  TRP   A H    1 
ATOM   4120 H  HA   . TRP   A 1 259 ? 60.527 -26.046 27.142 1.00 26.36  ?  951  TRP   A HA   1 
ATOM   4121 H  HB2  . TRP   A 1 259 ? 60.793 -27.576 24.576 1.00 30.64  ?  951  TRP   A HB2  1 
ATOM   4122 H  HB3  . TRP   A 1 259 ? 59.344 -27.245 25.505 1.00 30.64  ?  951  TRP   A HB3  1 
ATOM   4123 H  HD1  . TRP   A 1 259 ? 59.807 -24.108 25.875 1.00 30.40  ?  951  TRP   A HD1  1 
ATOM   4124 H  HE1  . TRP   A 1 259 ? 59.285 -22.563 23.913 1.00 36.01  ?  951  TRP   A HE1  1 
ATOM   4125 H  HE3  . TRP   A 1 259 ? 60.213 -27.508 22.053 1.00 37.23  ?  951  TRP   A HE3  1 
ATOM   4126 H  HZ2  . TRP   A 1 259 ? 59.092 -22.765 21.024 1.00 29.62  ?  951  TRP   A HZ2  1 
ATOM   4127 H  HZ3  . TRP   A 1 259 ? 59.853 -26.787 19.701 1.00 27.18  ?  951  TRP   A HZ3  1 
ATOM   4128 H  HH2  . TRP   A 1 259 ? 59.298 -24.420 19.184 1.00 37.73  ?  951  TRP   A HH2  1 
ATOM   4129 N  N    . MET   A 1 260 ? 62.559 -28.117 27.778 1.00 25.07  ?  952  MET   A N    1 
ATOM   4130 C  CA   . MET   A 1 260 ? 62.839 -29.270 28.629 1.00 41.51  ?  952  MET   A CA   1 
ATOM   4131 C  C    . MET   A 1 260 ? 61.963 -29.260 29.875 1.00 52.71  ?  952  MET   A C    1 
ATOM   4132 O  O    . MET   A 1 260 ? 61.688 -28.196 30.439 1.00 54.56  ?  952  MET   A O    1 
ATOM   4133 C  CB   . MET   A 1 260 ? 64.302 -29.273 29.070 1.00 38.93  ?  952  MET   A CB   1 
ATOM   4134 C  CG   . MET   A 1 260 ? 65.292 -29.330 27.916 1.00 59.47  ?  952  MET   A CG   1 
ATOM   4135 S  SD   . MET   A 1 260 ? 65.565 -30.978 27.261 1.00 54.33  ?  952  MET   A SD   1 
ATOM   4136 C  CE   . MET   A 1 260 ? 66.985 -31.451 28.243 1.00 59.45  ?  952  MET   A CE   1 
ATOM   4137 H  H    . MET   A 1 260 ? 63.250 -27.389 27.665 1.00 27.07  ?  952  MET   A H    1 
ATOM   4138 H  HA   . MET   A 1 260 ? 62.640 -30.178 28.057 1.00 43.51  ?  952  MET   A HA   1 
ATOM   4139 H  HB2  . MET   A 1 260 ? 64.496 -28.365 29.643 1.00 40.93  ?  952  MET   A HB2  1 
ATOM   4140 H  HB3  . MET   A 1 260 ? 64.498 -30.097 29.759 1.00 40.93  ?  952  MET   A HB3  1 
ATOM   4141 H  HG2  . MET   A 1 260 ? 64.926 -28.735 27.084 1.00 61.47  ?  952  MET   A HG2  1 
ATOM   4142 H  HG3  . MET   A 1 260 ? 66.247 -28.890 28.208 1.00 61.47  ?  952  MET   A HG3  1 
ATOM   4143 H  HE1  . MET   A 1 260 ? 67.362 -32.420 27.916 1.00 61.45  ?  952  MET   A HE1  1 
ATOM   4144 H  HE2  . MET   A 1 260 ? 67.790 -30.724 28.138 1.00 61.45  ?  952  MET   A HE2  1 
ATOM   4145 H  HE3  . MET   A 1 260 ? 66.716 -31.528 29.297 1.00 61.45  ?  952  MET   A HE3  1 
ATOM   4146 N  N    . ILE   A 1 261 ? 61.538 -30.441 30.306 1.00 56.45  ?  953  ILE   A N    1 
ATOM   4147 C  CA   . ILE   A 1 261 ? 60.723 -30.567 31.515 1.00 47.40  ?  953  ILE   A CA   1 
ATOM   4148 C  C    . ILE   A 1 261 ? 61.496 -30.133 32.767 1.00 51.75  ?  953  ILE   A C    1 
ATOM   4149 O  O    . ILE   A 1 261 ? 60.958 -29.443 33.637 1.00 44.47  ?  953  ILE   A O    1 
ATOM   4150 C  CB   . ILE   A 1 261 ? 60.189 -32.012 31.640 1.00 59.99  ?  953  ILE   A CB   1 
ATOM   4151 C  CG1  . ILE   A 1 261 ? 59.340 -32.478 30.450 1.00 60.59  ?  953  ILE   A CG1  1 
ATOM   4152 C  CG2  . ILE   A 1 261 ? 59.477 -32.325 32.955 1.00 62.48  ?  953  ILE   A CG2  1 
ATOM   4153 C  CD1  . ILE   A 1 261 ? 57.948 -31.872 30.354 1.00 58.48  ?  953  ILE   A CD1  1 
ATOM   4154 H  H    . ILE   A 1 261 ? 61.822 -31.287 29.815 1.00 58.45  ?  953  ILE   A H    1 
ATOM   4155 H  HA   . ILE   A 1 261 ? 59.868 -29.895 31.421 1.00 49.40  ?  953  ILE   A HA   1 
ATOM   4156 H  HB   . ILE   A 1 261 ? 61.075 -32.647 31.623 1.00 61.99  ?  953  ILE   A HB   1 
ATOM   4157 H  HG12 . ILE   A 1 261 ? 59.871 -32.310 29.514 1.00 62.59  ?  953  ILE   A HG12 1 
ATOM   4158 H  HG13 . ILE   A 1 261 ? 59.224 -33.561 30.504 1.00 62.59  ?  953  ILE   A HG13 1 
ATOM   4159 H  HG21 . ILE   A 1 261 ? 59.018 -33.313 32.927 1.00 64.48  ?  953  ILE   A HG21 1 
ATOM   4160 H  HG22 . ILE   A 1 261 ? 60.163 -32.318 33.803 1.00 64.48  ?  953  ILE   A HG22 1 
ATOM   4161 H  HG23 . ILE   A 1 261 ? 58.688 -31.602 33.163 1.00 64.48  ?  953  ILE   A HG23 1 
ATOM   4162 H  HD11 . ILE   A 1 261 ? 57.410 -32.279 29.497 1.00 60.48  ?  953  ILE   A HD11 1 
ATOM   4163 H  HD12 . ILE   A 1 261 ? 57.355 -32.110 31.233 1.00 60.48  ?  953  ILE   A HD12 1 
ATOM   4164 H  HD13 . ILE   A 1 261 ? 57.981 -30.788 30.240 1.00 60.48  ?  953  ILE   A HD13 1 
ATOM   4165 N  N    . ASP   A 1 262 ? 62.773 -30.506 32.834 1.00 43.16  ?  954  ASP   A N    1 
ATOM   4166 C  CA   . ASP   A 1 262 ? 63.632 -30.036 33.904 1.00 42.85  ?  954  ASP   A CA   1 
ATOM   4167 C  C    . ASP   A 1 262 ? 64.075 -28.604 33.611 1.00 50.84  ?  954  ASP   A C    1 
ATOM   4168 O  O    . ASP   A 1 262 ? 64.908 -28.345 32.736 1.00 50.69  ?  954  ASP   A O    1 
ATOM   4169 C  CB   . ASP   A 1 262 ? 64.846 -30.968 34.045 1.00 36.39  ?  954  ASP   A CB   1 
ATOM   4170 C  CG   . ASP   A 1 262 ? 65.864 -30.521 35.078 1.00 50.47  ?  954  ASP   A CG   1 
ATOM   4171 O  OD1  . ASP   A 1 262 ? 67.070 -30.782 34.888 1.00 63.19  ?  954  ASP   A OD1  1 
ATOM   4172 O  OD2  . ASP   A 1 262 ? 65.470 -29.898 36.086 1.00 79.41  -1 954  ASP   A OD2  1 
ATOM   4173 H  H    . ASP   A 1 262 ? 63.176 -31.113 32.120 1.00 45.16  ?  954  ASP   A H    1 
ATOM   4174 H  HA   . ASP   A 1 262 ? 63.084 -30.068 34.849 1.00 44.85  ?  954  ASP   A HA   1 
ATOM   4175 H  HB2  . ASP   A 1 262 ? 64.510 -31.970 34.314 1.00 38.39  ?  954  ASP   A HB2  1 
ATOM   4176 H  HB3  . ASP   A 1 262 ? 65.355 -31.066 33.085 1.00 38.39  ?  954  ASP   A HB3  1 
ATOM   4177 N  N    . ALA   A 1 263 ? 63.542 -27.686 34.407 1.00 53.11  ?  955  ALA   A N    1 
ATOM   4178 C  CA   . ALA   A 1 263 ? 63.845 -26.263 34.314 1.00 45.67  ?  955  ALA   A CA   1 
ATOM   4179 C  C    . ALA   A 1 263 ? 65.312 -25.875 34.349 1.00 44.86  ?  955  ALA   A C    1 
ATOM   4180 O  O    . ALA   A 1 263 ? 65.729 -24.923 33.681 1.00 46.68  ?  955  ALA   A O    1 
ATOM   4181 C  CB   . ALA   A 1 263 ? 63.089 -25.498 35.384 1.00 37.05  ?  955  ALA   A CB   1 
ATOM   4182 H  H    . ALA   A 1 263 ? 62.817 -27.988 35.042 1.00 55.11  ?  955  ALA   A H    1 
ATOM   4183 H  HA   . ALA   A 1 263 ? 63.469 -25.935 33.348 1.00 47.67  ?  955  ALA   A HA   1 
ATOM   4184 H  HB1  . ALA   A 1 263 ? 63.258 -24.424 35.301 1.00 39.05  ?  955  ALA   A HB1  1 
ATOM   4185 H  HB2  . ALA   A 1 263 ? 62.014 -25.660 35.299 1.00 39.05  ?  955  ALA   A HB2  1 
ATOM   4186 H  HB3  . ALA   A 1 263 ? 63.393 -25.802 36.387 1.00 39.05  ?  955  ALA   A HB3  1 
ATOM   4187 N  N    . ASP   A 1 264 ? 66.091 -26.643 35.100 1.00 45.34  ?  956  ASP   A N    1 
ATOM   4188 C  CA   . ASP   A 1 264 ? 67.528 -26.389 35.212 1.00 51.62  ?  956  ASP   A CA   1 
ATOM   4189 C  C    . ASP   A 1 264 ? 68.349 -26.939 34.057 1.00 46.03  ?  956  ASP   A C    1 
ATOM   4190 O  O    . ASP   A 1 264 ? 69.523 -26.599 33.922 1.00 45.58  ?  956  ASP   A O    1 
ATOM   4191 C  CB   . ASP   A 1 264 ? 68.080 -27.025 36.486 1.00 66.80  ?  956  ASP   A CB   1 
ATOM   4192 C  CG   . ASP   A 1 264 ? 67.620 -26.281 37.715 1.00 72.91  ?  956  ASP   A CG   1 
ATOM   4193 O  OD1  . ASP   A 1 264 ? 67.010 -26.906 38.605 1.00 72.28  ?  956  ASP   A OD1  1 
ATOM   4194 O  OD2  . ASP   A 1 264 ? 67.866 -25.059 37.806 1.00 83.80  -1 956  ASP   A OD2  1 
ATOM   4195 H  H    . ASP   A 1 264 ? 65.694 -27.438 35.587 1.00 47.34  ?  956  ASP   A H    1 
ATOM   4196 H  HA   . ASP   A 1 264 ? 67.716 -25.312 35.235 1.00 53.62  ?  956  ASP   A HA   1 
ATOM   4197 H  HB2  . ASP   A 1 264 ? 67.787 -28.075 36.554 1.00 68.80  ?  956  ASP   A HB2  1 
ATOM   4198 H  HB3  . ASP   A 1 264 ? 69.172 -27.012 36.500 1.00 68.80  ?  956  ASP   A HB3  1 
ATOM   4199 N  N    . SER   A 1 265 ? 67.736 -27.764 33.222 1.00 36.86  ?  957  SER   A N    1 
ATOM   4200 C  CA   . SER   A 1 265 ? 68.389 -28.188 31.991 1.00 49.28  ?  957  SER   A CA   1 
ATOM   4201 C  C    . SER   A 1 265 ? 68.065 -27.249 30.831 1.00 49.54  ?  957  SER   A C    1 
ATOM   4202 O  O    . SER   A 1 265 ? 68.628 -27.389 29.742 1.00 45.18  ?  957  SER   A O    1 
ATOM   4203 C  CB   . SER   A 1 265 ? 67.977 -29.619 31.632 1.00 46.54  ?  957  SER   A CB   1 
ATOM   4204 O  OG   . SER   A 1 265 ? 68.636 -30.559 32.479 1.00 64.02  ?  957  SER   A OG   1 
ATOM   4205 H  H    . SER   A 1 265 ? 66.762 -28.014 33.362 1.00 38.86  ?  957  SER   A H    1 
ATOM   4206 H  HA   . SER   A 1 265 ? 69.476 -28.178 32.076 1.00 51.28  ?  957  SER   A HA   1 
ATOM   4207 H  HB2  . SER   A 1 265 ? 66.895 -29.758 31.676 1.00 48.54  ?  957  SER   A HB2  1 
ATOM   4208 H  HB3  . SER   A 1 265 ? 68.275 -29.857 30.609 1.00 48.54  ?  957  SER   A HB3  1 
ATOM   4209 H  HG   . SER   A 1 265 ? 68.193 -30.556 33.325 1.00 66.02  ?  957  SER   A HG   1 
ATOM   4210 N  N    . ARG   A 1 266 ? 67.181 -26.271 31.055 1.00 31.28  ?  958  ARG   A N    1 
ATOM   4211 C  CA   . ARG   A 1 266 ? 66.972 -25.237 30.046 1.00 34.17  ?  958  ARG   A CA   1 
ATOM   4212 C  C    . ARG   A 1 266 ? 68.163 -24.283 30.051 1.00 31.40  ?  958  ARG   A C    1 
ATOM   4213 O  O    . ARG   A 1 266 ? 68.788 -24.101 31.104 1.00 43.39  ?  958  ARG   A O    1 
ATOM   4214 C  CB   . ARG   A 1 266 ? 65.694 -24.449 30.315 1.00 42.55  ?  958  ARG   A CB   1 
ATOM   4215 C  CG   . ARG   A 1 266 ? 64.435 -25.299 30.293 1.00 36.06  ?  958  ARG   A CG   1 
ATOM   4216 C  CD   . ARG   A 1 266 ? 63.196 -24.541 30.741 1.00 37.18  ?  958  ARG   A CD   1 
ATOM   4217 N  NE   . ARG   A 1 266 ? 62.174 -25.523 31.133 1.00 51.69  ?  958  ARG   A NE   1 
ATOM   4218 C  CZ   . ARG   A 1 266 ? 61.259 -25.320 32.091 1.00 45.24  ?  958  ARG   A CZ   1 
ATOM   4219 N  NH1  . ARG   A 1 266 ? 61.192 -24.151 32.737 1.00 40.22  ?  958  ARG   A NH1  1 
ATOM   4220 N  NH2  . ARG   A 1 266 ? 60.410 -26.298 32.406 1.00 42.22  1  958  ARG   A NH2  1 
ATOM   4221 H  H    . ARG   A 1 266 ? 66.824 -26.138 31.990 1.00 33.28  ?  958  ARG   A H    1 
ATOM   4222 H  HA   . ARG   A 1 266 ? 66.886 -25.725 29.078 1.00 36.17  ?  958  ARG   A HA   1 
ATOM   4223 H  HB2  . ARG   A 1 266 ? 65.776 -23.959 31.282 1.00 44.55  ?  958  ARG   A HB2  1 
ATOM   4224 H  HB3  . ARG   A 1 266 ? 65.580 -23.643 29.591 1.00 44.55  ?  958  ARG   A HB3  1 
ATOM   4225 H  HG2  . ARG   A 1 266 ? 64.273 -25.696 29.292 1.00 38.06  ?  958  ARG   A HG2  1 
ATOM   4226 H  HG3  . ARG   A 1 266 ? 64.571 -26.168 30.939 1.00 38.06  ?  958  ARG   A HG3  1 
ATOM   4227 H  HD2  . ARG   A 1 266 ? 63.457 -23.934 31.606 1.00 39.18  ?  958  ARG   A HD2  1 
ATOM   4228 H  HD3  . ARG   A 1 266 ? 62.821 -23.859 29.980 1.00 39.18  ?  958  ARG   A HD3  1 
ATOM   4229 H  HE   . ARG   A 1 266 ? 62.183 -26.418 30.650 1.00 53.69  ?  958  ARG   A HE   1 
ATOM   4230 H  HH11 . ARG   A 1 266 ? 61.814 -23.391 32.489 1.00 42.22  ?  958  ARG   A HH11 1 
ATOM   4231 H  HH12 . ARG   A 1 266 ? 60.507 -24.025 33.483 1.00 42.22  ?  958  ARG   A HH12 1 
ATOM   4232 H  HH21 . ARG   A 1 266 ? 60.467 -27.192 31.934 1.00 44.22  ?  958  ARG   A HH21 1 
ATOM   4233 H  HH22 . ARG   A 1 266 ? 59.711 -26.153 33.136 1.00 44.22  ?  958  ARG   A HH22 1 
ATOM   4234 N  N    . PRO   A 1 267 ? 68.492 -23.645 28.918 1.00 37.87  ?  959  PRO   A N    1 
ATOM   4235 C  CA   . PRO   A 1 267 ? 69.555 -22.656 28.878 1.00 37.93  ?  959  PRO   A CA   1 
ATOM   4236 C  C    . PRO   A 1 267 ? 69.238 -21.451 29.737 1.00 37.62  ?  959  PRO   A C    1 
ATOM   4237 O  O    . PRO   A 1 267 ? 68.080 -21.164 30.053 1.00 29.51  ?  959  PRO   A O    1 
ATOM   4238 C  CB   . PRO   A 1 267 ? 69.742 -22.313 27.411 1.00 36.09  ?  959  PRO   A CB   1 
ATOM   4239 C  CG   . PRO   A 1 267 ? 68.459 -22.772 26.713 1.00 35.55  ?  959  PRO   A CG   1 
ATOM   4240 C  CD   . PRO   A 1 267 ? 67.825 -23.816 27.632 1.00 34.27  ?  959  PRO   A CD   1 
ATOM   4241 H  HA   . PRO   A 1 267 ? 70.470 -23.119 29.255 1.00 39.93  ?  959  PRO   A HA   1 
ATOM   4242 H  HB2  . PRO   A 1 267 ? 69.957 -21.259 27.232 1.00 38.09  ?  959  PRO   A HB2  1 
ATOM   4243 H  HB3  . PRO   A 1 267 ? 70.590 -22.876 27.016 1.00 38.09  ?  959  PRO   A HB3  1 
ATOM   4244 H  HG2  . PRO   A 1 267 ? 67.776 -21.925 26.643 1.00 37.55  ?  959  PRO   A HG2  1 
ATOM   4245 H  HG3  . PRO   A 1 267 ? 68.628 -23.141 25.700 1.00 37.55  ?  959  PRO   A HG3  1 
ATOM   4246 H  HD2  . PRO   A 1 267 ? 66.748 -23.683 27.682 1.00 36.27  ?  959  PRO   A HD2  1 
ATOM   4247 H  HD3  . PRO   A 1 267 ? 68.040 -24.820 27.283 1.00 36.27  ?  959  PRO   A HD3  1 
ATOM   4248 N  N    . LYS   A 1 268 ? 70.294 -20.785 30.159 1.00 37.43  ?  960  LYS   A N    1 
ATOM   4249 C  CA   . LYS   A 1 268 ? 70.115 -19.505 30.816 1.00 44.79  ?  960  LYS   A CA   1 
ATOM   4250 C  C    . LYS   A 1 268 ? 70.097 -18.416 29.753 1.00 38.61  ?  960  LYS   A C    1 
ATOM   4251 O  O    . LYS   A 1 268 ? 70.757 -18.538 28.713 1.00 36.52  ?  960  LYS   A O    1 
ATOM   4252 C  CB   . LYS   A 1 268 ? 71.255 -19.267 31.813 1.00 49.84  ?  960  LYS   A CB   1 
ATOM   4253 C  CG   . LYS   A 1 268 ? 70.959 -19.790 33.226 1.00 59.68  ?  960  LYS   A CG   1 
ATOM   4254 C  CD   . LYS   A 1 268 ? 70.773 -21.301 33.341 1.00 68.90  ?  960  LYS   A CD   1 
ATOM   4255 C  CE   . LYS   A 1 268 ? 70.399 -21.752 34.749 1.00 86.80  ?  960  LYS   A CE   1 
ATOM   4256 N  NZ   . LYS   A 1 268 ? 70.175 -23.209 34.816 1.00 86.91  1  960  LYS   A NZ   1 
ATOM   4257 H  H    . LYS   A 1 268 ? 71.217 -21.050 29.833 1.00 39.43  ?  960  LYS   A H    1 
ATOM   4258 H  HA   . LYS   A 1 268 ? 69.172 -19.480 31.357 1.00 46.79  ?  960  LYS   A HA   1 
ATOM   4259 H  HB2  . LYS   A 1 268 ? 72.192 -19.680 31.442 1.00 51.84  ?  960  LYS   A HB2  1 
ATOM   4260 H  HB3  . LYS   A 1 268 ? 71.431 -18.194 31.914 1.00 51.84  ?  960  LYS   A HB3  1 
ATOM   4261 H  HG2  . LYS   A 1 268 ? 71.768 -19.480 33.888 1.00 61.68  ?  960  LYS   A HG2  1 
ATOM   4262 H  HG3  . LYS   A 1 268 ? 70.065 -19.290 33.603 1.00 61.68  ?  960  LYS   A HG3  1 
ATOM   4263 H  HD2  . LYS   A 1 268 ? 69.976 -21.623 32.671 1.00 70.90  ?  960  LYS   A HD2  1 
ATOM   4264 H  HD3  . LYS   A 1 268 ? 71.679 -21.810 33.010 1.00 70.90  ?  960  LYS   A HD3  1 
ATOM   4265 H  HE2  . LYS   A 1 268 ? 71.174 -21.479 35.465 1.00 88.80  ?  960  LYS   A HE2  1 
ATOM   4266 H  HE3  . LYS   A 1 268 ? 69.482 -21.252 35.065 1.00 88.80  ?  960  LYS   A HE3  1 
ATOM   4267 H  HZ1  . LYS   A 1 268 ? 69.665 -23.441 35.658 1.00 88.91  ?  960  LYS   A HZ1  1 
ATOM   4268 H  HZ2  . LYS   A 1 268 ? 69.648 -23.514 34.010 1.00 88.91  ?  960  LYS   A HZ2  1 
ATOM   4269 H  HZ3  . LYS   A 1 268 ? 71.064 -23.687 34.827 1.00 88.91  ?  960  LYS   A HZ3  1 
ATOM   4270 N  N    . PHE   A 1 269 ? 69.373 -17.337 30.033 1.00 31.78  ?  961  PHE   A N    1 
ATOM   4271 C  CA   . PHE   A 1 269 ? 69.363 -16.156 29.168 1.00 26.77  ?  961  PHE   A CA   1 
ATOM   4272 C  C    . PHE   A 1 269 ? 70.719 -15.656 28.688 1.00 36.83  ?  961  PHE   A C    1 
ATOM   4273 O  O    . PHE   A 1 269 ? 70.887 -15.360 27.501 1.00 25.32  ?  961  PHE   A O    1 
ATOM   4274 C  CB   . PHE   A 1 269 ? 68.514 -15.022 29.717 1.00 29.15  ?  961  PHE   A CB   1 
ATOM   4275 C  CG   . PHE   A 1 269 ? 67.019 -15.258 29.629 1.00 24.17  ?  961  PHE   A CG   1 
ATOM   4276 C  CD1  . PHE   A 1 269 ? 66.404 -15.407 28.372 1.00 25.77  ?  961  PHE   A CD1  1 
ATOM   4277 C  CD2  . PHE   A 1 269 ? 66.243 -15.322 30.802 1.00 25.85  ?  961  PHE   A CD2  1 
ATOM   4278 C  CE1  . PHE   A 1 269 ? 65.019 -15.619 28.286 1.00 26.58  ?  961  PHE   A CE1  1 
ATOM   4279 C  CE2  . PHE   A 1 269 ? 64.856 -15.535 30.715 1.00 20.11  ?  961  PHE   A CE2  1 
ATOM   4280 C  CZ   . PHE   A 1 269 ? 64.243 -15.683 29.454 1.00 25.69  ?  961  PHE   A CZ   1 
ATOM   4281 H  H    . PHE   A 1 269 ? 68.823 -17.329 30.895 1.00 33.78  ?  961  PHE   A H    1 
ATOM   4282 H  HA   . PHE   A 1 269 ? 68.887 -16.490 28.248 1.00 28.77  ?  961  PHE   A HA   1 
ATOM   4283 H  HB2  . PHE   A 1 269 ? 68.801 -14.795 30.744 1.00 31.15  ?  961  PHE   A HB2  1 
ATOM   4284 H  HB3  . PHE   A 1 269 ? 68.703 -14.109 29.150 1.00 31.15  ?  961  PHE   A HB3  1 
ATOM   4285 H  HD1  . PHE   A 1 269 ? 66.997 -15.355 27.469 1.00 27.77  ?  961  PHE   A HD1  1 
ATOM   4286 H  HD2  . PHE   A 1 269 ? 66.710 -15.208 31.769 1.00 27.85  ?  961  PHE   A HD2  1 
ATOM   4287 H  HE1  . PHE   A 1 269 ? 64.553 -15.731 27.322 1.00 28.58  ?  961  PHE   A HE1  1 
ATOM   4288 H  HE2  . PHE   A 1 269 ? 64.261 -15.585 31.615 1.00 22.11  ?  961  PHE   A HE2  1 
ATOM   4289 H  HZ   . PHE   A 1 269 ? 63.180 -15.843 29.386 1.00 27.69  ?  961  PHE   A HZ   1 
ATOM   4290 N  N    . ARG   A 1 270 ? 71.717 -15.671 29.571 1.00 22.60  ?  962  ARG   A N    1 
ATOM   4291 C  CA   . ARG   A 1 270 ? 73.056 -15.271 29.144 1.00 34.67  ?  962  ARG   A CA   1 
ATOM   4292 C  C    . ARG   A 1 270 ? 73.662 -16.150 28.048 1.00 30.63  ?  962  ARG   A C    1 
ATOM   4293 O  O    . ARG   A 1 270 ? 74.479 -15.691 27.245 1.00 32.42  ?  962  ARG   A O    1 
ATOM   4294 C  CB   . ARG   A 1 270 ? 74.002 -15.161 30.337 1.00 38.38  ?  962  ARG   A CB   1 
ATOM   4295 C  CG   . ARG   A 1 270 ? 74.475 -16.487 30.944 1.00 54.37  ?  962  ARG   A CG   1 
ATOM   4296 C  CD   . ARG   A 1 270 ? 75.602 -16.324 31.941 1.00 56.33  ?  962  ARG   A CD   1 
ATOM   4297 N  NE   . ARG   A 1 270 ? 76.852 -15.883 31.293 1.00 74.31  ?  962  ARG   A NE   1 
ATOM   4298 C  CZ   . ARG   A 1 270 ? 77.788 -16.711 30.793 1.00 69.73  ?  962  ARG   A CZ   1 
ATOM   4299 N  NH1  . ARG   A 1 270 ? 77.620 -18.038 30.831 1.00 69.29  ?  962  ARG   A NH1  1 
ATOM   4300 N  NH2  . ARG   A 1 270 ? 78.898 -16.202 30.256 1.00 72.09  1  962  ARG   A NH2  1 
ATOM   4301 H  H    . ARG   A 1 270 ? 71.508 -15.837 30.556 1.00 24.60  ?  962  ARG   A H    1 
ATOM   4302 H  HA   . ARG   A 1 270 ? 72.967 -14.269 28.728 1.00 36.67  ?  962  ARG   A HA   1 
ATOM   4303 H  HB2  . ARG   A 1 270 ? 74.875 -14.595 30.007 1.00 40.38  ?  962  ARG   A HB2  1 
ATOM   4304 H  HB3  . ARG   A 1 270 ? 73.544 -14.545 31.113 1.00 40.38  ?  962  ARG   A HB3  1 
ATOM   4305 H  HG2  . ARG   A 1 270 ? 73.634 -16.996 31.415 1.00 56.37  ?  962  ARG   A HG2  1 
ATOM   4306 H  HG3  . ARG   A 1 270 ? 74.847 -17.164 30.177 1.00 56.37  ?  962  ARG   A HG3  1 
ATOM   4307 H  HD2  . ARG   A 1 270 ? 75.322 -15.562 32.665 1.00 58.33  ?  962  ARG   A HD2  1 
ATOM   4308 H  HD3  . ARG   A 1 270 ? 75.768 -17.244 32.501 1.00 58.33  ?  962  ARG   A HD3  1 
ATOM   4309 H  HE   . ARG   A 1 270 ? 77.010 -14.878 31.234 1.00 76.31  ?  962  ARG   A HE   1 
ATOM   4310 H  HH11 . ARG   A 1 270 ? 76.785 -18.434 31.233 1.00 71.29  ?  962  ARG   A HH11 1 
ATOM   4311 H  HH12 . ARG   A 1 270 ? 78.340 -18.650 30.460 1.00 71.29  ?  962  ARG   A HH12 1 
ATOM   4312 H  HH21 . ARG   A 1 270 ? 79.032 -15.201 30.219 1.00 74.09  ?  962  ARG   A HH21 1 
ATOM   4313 H  HH22 . ARG   A 1 270 ? 79.616 -16.822 29.894 1.00 74.09  ?  962  ARG   A HH22 1 
ATOM   4314 N  N    . GLU   A 1 271 ? 73.252 -17.414 28.032 1.00 28.33  ?  963  GLU   A N    1 
ATOM   4315 C  CA   . GLU   A 1 271 ? 73.774 -18.380 27.077 1.00 36.44  ?  963  GLU   A CA   1 
ATOM   4316 C  C    . GLU   A 1 271 ? 73.027 -18.274 25.761 1.00 28.40  ?  963  GLU   A C    1 
ATOM   4317 O  O    . GLU   A 1 271 ? 73.631 -18.378 24.700 1.00 39.47  ?  963  GLU   A O    1 
ATOM   4318 C  CB   . GLU   A 1 271 ? 73.629 -19.800 27.627 1.00 36.83  ?  963  GLU   A CB   1 
ATOM   4319 C  CG   . GLU   A 1 271 ? 74.282 -19.949 29.013 1.00 41.33  ?  963  GLU   A CG   1 
ATOM   4320 C  CD   . GLU   A 1 271 ? 73.973 -21.308 29.611 1.00 38.68  ?  963  GLU   A CD   1 
ATOM   4321 O  OE1  . GLU   A 1 271 ? 72.876 -21.851 29.360 1.00 42.14  ?  963  GLU   A OE1  1 
ATOM   4322 O  OE2  . GLU   A 1 271 ? 74.821 -21.837 30.358 1.00 51.60  -1 963  GLU   A OE2  1 
ATOM   4323 H  H    . GLU   A 1 271 ? 72.473 -17.699 28.617 1.00 30.33  ?  963  GLU   A H    1 
ATOM   4324 H  HA   . GLU   A 1 271 ? 74.834 -18.194 26.892 1.00 38.44  ?  963  GLU   A HA   1 
ATOM   4325 H  HB2  . GLU   A 1 271 ? 72.571 -20.068 27.661 1.00 38.83  ?  963  GLU   A HB2  1 
ATOM   4326 H  HB3  . GLU   A 1 271 ? 74.091 -20.505 26.933 1.00 38.83  ?  963  GLU   A HB3  1 
ATOM   4327 H  HG2  . GLU   A 1 271 ? 75.361 -19.809 28.951 1.00 43.33  ?  963  GLU   A HG2  1 
ATOM   4328 H  HG3  . GLU   A 1 271 ? 73.892 -19.218 29.718 1.00 43.33  ?  963  GLU   A HG3  1 
ATOM   4329 N  N    . LEU   A 1 272 ? 71.733 -17.966 25.837 1.00 32.84  ?  964  LEU   A N    1 
ATOM   4330 C  CA   . LEU   A 1 272 ? 70.943 -17.617 24.660 1.00 33.32  ?  964  LEU   A CA   1 
ATOM   4331 C  C    . LEU   A 1 272 ? 71.472 -16.387 23.923 1.00 39.56  ?  964  LEU   A C    1 
ATOM   4332 O  O    . LEU   A 1 272 ? 71.558 -16.391 22.693 1.00 40.41  ?  964  LEU   A O    1 
ATOM   4333 C  CB   . LEU   A 1 272 ? 69.465 -17.445 25.023 1.00 24.03  ?  964  LEU   A CB   1 
ATOM   4334 C  CG   . LEU   A 1 272 ? 68.786 -18.717 25.550 1.00 34.38  ?  964  LEU   A CG   1 
ATOM   4335 C  CD1  . LEU   A 1 272 ? 67.462 -18.417 26.229 1.00 26.55  ?  964  LEU   A CD1  1 
ATOM   4336 C  CD2  . LEU   A 1 272 ? 68.566 -19.748 24.454 1.00 19.13  ?  964  LEU   A CD2  1 
ATOM   4337 H  H    . LEU   A 1 272 ? 71.306 -17.901 26.753 1.00 34.84  ?  964  LEU   A H    1 
ATOM   4338 H  HA   . LEU   A 1 272 ? 71.031 -18.443 23.954 1.00 35.32  ?  964  LEU   A HA   1 
ATOM   4339 H  HB2  . LEU   A 1 272 ? 69.376 -16.655 25.769 1.00 26.03  ?  964  LEU   A HB2  1 
ATOM   4340 H  HB3  . LEU   A 1 272 ? 68.911 -17.081 24.155 1.00 26.03  ?  964  LEU   A HB3  1 
ATOM   4341 H  HG   . LEU   A 1 272 ? 69.423 -19.172 26.308 1.00 36.38  ?  964  LEU   A HG   1 
ATOM   4342 H  HD11 . LEU   A 1 272 ? 66.910 -19.331 26.441 1.00 28.55  ?  964  LEU   A HD11 1 
ATOM   4343 H  HD12 . LEU   A 1 272 ? 67.605 -17.913 27.183 1.00 28.55  ?  964  LEU   A HD12 1 
ATOM   4344 H  HD13 . LEU   A 1 272 ? 66.829 -17.780 25.616 1.00 28.55  ?  964  LEU   A HD13 1 
ATOM   4345 H  HD21 . LEU   A 1 272 ? 68.051 -20.633 24.824 1.00 21.13  ?  964  LEU   A HD21 1 
ATOM   4346 H  HD22 . LEU   A 1 272 ? 67.955 -19.342 23.648 1.00 21.13  ?  964  LEU   A HD22 1 
ATOM   4347 H  HD23 . LEU   A 1 272 ? 69.505 -20.089 24.019 1.00 21.13  ?  964  LEU   A HD23 1 
ATOM   4348 N  N    . ILE   A 1 273 ? 71.920 -15.379 24.675 1.00 34.74  ?  965  ILE   A N    1 
ATOM   4349 C  CA   . ILE   A 1 273 ? 72.632 -14.244 24.082 1.00 27.79  ?  965  ILE   A CA   1 
ATOM   4350 C  C    . ILE   A 1 273 ? 73.854 -14.692 23.296 1.00 29.39  ?  965  ILE   A C    1 
ATOM   4351 O  O    . ILE   A 1 273 ? 74.018 -14.324 22.133 1.00 32.92  ?  965  ILE   A O    1 
ATOM   4352 C  CB   . ILE   A 1 273 ? 73.013 -13.175 25.128 1.00 25.94  ?  965  ILE   A CB   1 
ATOM   4353 C  CG1  . ILE   A 1 273 ? 71.792 -12.596 25.838 1.00 20.15  ?  965  ILE   A CG1  1 
ATOM   4354 C  CG2  . ILE   A 1 273 ? 73.866 -12.035 24.561 1.00 12.74  ?  965  ILE   A CG2  1 
ATOM   4355 C  CD1  . ILE   A 1 273 ? 72.142 -11.812 27.100 1.00 25.88  ?  965  ILE   A CD1  1 
ATOM   4356 H  H    . ILE   A 1 273 ? 71.786 -15.419 25.681 1.00 36.74  ?  965  ILE   A H    1 
ATOM   4357 H  HA   . ILE   A 1 273 ? 71.950 -13.777 23.366 1.00 29.79  ?  965  ILE   A HA   1 
ATOM   4358 H  HB   . ILE   A 1 273 ? 73.622 -13.671 25.884 1.00 27.94  ?  965  ILE   A HB   1 
ATOM   4359 H  HG12 . ILE   A 1 273 ? 71.225 -11.964 25.155 1.00 22.15  ?  965  ILE   A HG12 1 
ATOM   4360 H  HG13 . ILE   A 1 273 ? 71.111 -13.388 26.128 1.00 22.15  ?  965  ILE   A HG13 1 
ATOM   4361 H  HG21 . ILE   A 1 273 ? 74.138 -11.309 25.326 1.00 14.74  ?  965  ILE   A HG21 1 
ATOM   4362 H  HG22 . ILE   A 1 273 ? 74.814 -12.377 24.146 1.00 14.74  ?  965  ILE   A HG22 1 
ATOM   4363 H  HG23 . ILE   A 1 273 ? 73.337 -11.499 23.773 1.00 14.74  ?  965  ILE   A HG23 1 
ATOM   4364 H  HD11 . ILE   A 1 273 ? 71.251 -11.644 27.698 1.00 27.88  ?  965  ILE   A HD11 1 
ATOM   4365 H  HD12 . ILE   A 1 273 ? 72.860 -12.339 27.725 1.00 27.88  ?  965  ILE   A HD12 1 
ATOM   4366 H  HD13 . ILE   A 1 273 ? 72.570 -10.838 26.872 1.00 27.88  ?  965  ILE   A HD13 1 
ATOM   4367 N  N    . ILE   A 1 274 ? 74.685 -15.505 23.937 1.00 27.64  ?  966  ILE   A N    1 
ATOM   4368 C  CA   . ILE   A 1 274 ? 75.885 -16.048 23.314 1.00 30.19  ?  966  ILE   A CA   1 
ATOM   4369 C  C    . ILE   A 1 274 ? 75.590 -16.836 22.034 1.00 34.50  ?  966  ILE   A C    1 
ATOM   4370 O  O    . ILE   A 1 274 ? 76.112 -16.528 20.956 1.00 31.05  ?  966  ILE   A O    1 
ATOM   4371 C  CB   . ILE   A 1 274 ? 76.714 -16.814 24.369 1.00 31.77  ?  966  ILE   A CB   1 
ATOM   4372 C  CG1  . ILE   A 1 274 ? 77.310 -15.849 25.399 1.00 41.16  ?  966  ILE   A CG1  1 
ATOM   4373 C  CG2  . ILE   A 1 274 ? 77.805 -17.696 23.783 1.00 26.41  ?  966  ILE   A CG2  1 
ATOM   4374 C  CD1  . ILE   A 1 274 ? 77.772 -16.507 26.694 1.00 27.57  ?  966  ILE   A CD1  1 
ATOM   4375 H  H    . ILE   A 1 274 ? 74.456 -15.793 24.879 1.00 29.64  ?  966  ILE   A H    1 
ATOM   4376 H  HA   . ILE   A 1 274 ? 76.487 -15.195 22.992 1.00 32.19  ?  966  ILE   A HA   1 
ATOM   4377 H  HB   . ILE   A 1 274 ? 76.035 -17.483 24.897 1.00 33.77  ?  966  ILE   A HB   1 
ATOM   4378 H  HG12 . ILE   A 1 274 ? 78.135 -15.290 24.960 1.00 43.16  ?  966  ILE   A HG12 1 
ATOM   4379 H  HG13 . ILE   A 1 274 ? 76.571 -15.096 25.667 1.00 43.16  ?  966  ILE   A HG13 1 
ATOM   4380 H  HG21 . ILE   A 1 274 ? 78.428 -18.149 24.551 1.00 28.41  ?  966  ILE   A HG21 1 
ATOM   4381 H  HG22 . ILE   A 1 274 ? 77.387 -18.526 23.213 1.00 28.41  ?  966  ILE   A HG22 1 
ATOM   4382 H  HG23 . ILE   A 1 274 ? 78.442 -17.122 23.117 1.00 28.41  ?  966  ILE   A HG23 1 
ATOM   4383 H  HD11 . ILE   A 1 274 ? 78.065 -15.749 27.421 1.00 29.57  ?  966  ILE   A HD11 1 
ATOM   4384 H  HD12 . ILE   A 1 274 ? 76.974 -17.094 27.150 1.00 29.57  ?  966  ILE   A HD12 1 
ATOM   4385 H  HD13 . ILE   A 1 274 ? 78.628 -17.163 26.546 1.00 29.57  ?  966  ILE   A HD13 1 
ATOM   4386 N  N    . GLU   A 1 275 ? 74.705 -17.813 22.154 1.00 24.36  ?  967  GLU   A N    1 
ATOM   4387 C  CA   . GLU   A 1 275 ? 74.388 -18.690 21.040 1.00 25.69  ?  967  GLU   A CA   1 
ATOM   4388 C  C    . GLU   A 1 275 ? 73.752 -17.980 19.853 1.00 26.76  ?  967  GLU   A C    1 
ATOM   4389 O  O    . GLU   A 1 275 ? 74.223 -18.118 18.718 1.00 37.62  ?  967  GLU   A O    1 
ATOM   4390 C  CB   . GLU   A 1 275 ? 73.543 -19.873 21.544 1.00 24.32  ?  967  GLU   A CB   1 
ATOM   4391 C  CG   . GLU   A 1 275 ? 74.137 -21.256 21.233 1.00 61.23  ?  967  GLU   A CG   1 
ATOM   4392 C  CD   . GLU   A 1 275 ? 75.532 -21.377 21.828 1.00 56.74  ?  967  GLU   A CD   1 
ATOM   4393 O  OE1  . GLU   A 1 275 ? 75.683 -21.210 23.055 1.00 71.77  ?  967  GLU   A OE1  1 
ATOM   4394 O  OE2  . GLU   A 1 275 ? 76.491 -21.625 21.071 1.00 70.93  -1 967  GLU   A OE2  1 
ATOM   4395 H  H    . GLU   A 1 275 ? 74.296 -18.010 23.067 1.00 26.36  ?  967  GLU   A H    1 
ATOM   4396 H  HA   . GLU   A 1 275 ? 75.343 -19.053 20.657 1.00 27.69  ?  967  GLU   A HA   1 
ATOM   4397 H  HB2  . GLU   A 1 275 ? 73.379 -19.811 22.619 1.00 26.32  ?  967  GLU   A HB2  1 
ATOM   4398 H  HB3  . GLU   A 1 275 ? 72.538 -19.829 21.123 1.00 26.32  ?  967  GLU   A HB3  1 
ATOM   4399 H  HG2  . GLU   A 1 275 ? 73.505 -22.044 21.643 1.00 63.23  ?  967  GLU   A HG2  1 
ATOM   4400 H  HG3  . GLU   A 1 275 ? 74.185 -21.418 20.156 1.00 63.23  ?  967  GLU   A HG3  1 
ATOM   4401 N  N    . PHE   A 1 276 ? 72.749 -17.137 20.108 1.00 30.55  ?  968  PHE   A N    1 
ATOM   4402 C  CA   . PHE   A 1 276 ? 72.170 -16.371 19.004 1.00 21.76  ?  968  PHE   A CA   1 
ATOM   4403 C  C    . PHE   A 1 276 ? 73.106 -15.311 18.425 1.00 31.43  ?  968  PHE   A C    1 
ATOM   4404 O  O    . PHE   A 1 276 ? 73.026 -14.996 17.234 1.00 22.95  ?  968  PHE   A O    1 
ATOM   4405 C  CB   . PHE   A 1 276 ? 70.820 -15.777 19.381 1.00 24.32  ?  968  PHE   A CB   1 
ATOM   4406 C  CG   . PHE   A 1 276 ? 69.679 -16.788 19.315 1.00 25.88  ?  968  PHE   A CG   1 
ATOM   4407 C  CD1  . PHE   A 1 276 ? 69.105 -17.121 18.070 1.00 20.34  ?  968  PHE   A CD1  1 
ATOM   4408 C  CD2  . PHE   A 1 276 ? 69.193 -17.391 20.492 1.00 22.37  ?  968  PHE   A CD2  1 
ATOM   4409 C  CE1  . PHE   A 1 276 ? 68.058 -18.062 18.003 1.00 21.85  ?  968  PHE   A CE1  1 
ATOM   4410 C  CE2  . PHE   A 1 276 ? 68.144 -18.332 20.423 1.00 26.60  ?  968  PHE   A CE2  1 
ATOM   4411 C  CZ   . PHE   A 1 276 ? 67.579 -18.670 19.179 1.00 21.20  ?  968  PHE   A CZ   1 
ATOM   4412 H  H    . PHE   A 1 276 ? 72.409 -16.997 21.057 1.00 32.55  ?  968  PHE   A H    1 
ATOM   4413 H  HA   . PHE   A 1 276 ? 71.989 -17.052 18.175 1.00 23.76  ?  968  PHE   A HA   1 
ATOM   4414 H  HB2  . PHE   A 1 276 ? 70.856 -15.305 20.364 1.00 26.32  ?  968  PHE   A HB2  1 
ATOM   4415 H  HB3  . PHE   A 1 276 ? 70.553 -14.981 18.684 1.00 26.32  ?  968  PHE   A HB3  1 
ATOM   4416 H  HD1  . PHE   A 1 276 ? 69.469 -16.656 17.167 1.00 22.34  ?  968  PHE   A HD1  1 
ATOM   4417 H  HD2  . PHE   A 1 276 ? 69.621 -17.135 21.448 1.00 24.37  ?  968  PHE   A HD2  1 
ATOM   4418 H  HE1  . PHE   A 1 276 ? 67.621 -18.316 17.048 1.00 23.85  ?  968  PHE   A HE1  1 
ATOM   4419 H  HE2  . PHE   A 1 276 ? 67.773 -18.793 21.326 1.00 28.60  ?  968  PHE   A HE2  1 
ATOM   4420 H  HZ   . PHE   A 1 276 ? 66.777 -19.391 19.128 1.00 23.20  ?  968  PHE   A HZ   1 
ATOM   4421 N  N    . SER   A 1 277 ? 74.049 -14.818 19.225 1.00 19.77  ?  969  SER   A N    1 
ATOM   4422 C  CA   . SER   A 1 277 ? 75.025 -13.862 18.697 1.00 25.88  ?  969  SER   A CA   1 
ATOM   4423 C  C    . SER   A 1 277 ? 76.045 -14.506 17.766 1.00 31.48  ?  969  SER   A C    1 
ATOM   4424 O  O    . SER   A 1 277 ? 76.431 -13.904 16.764 1.00 37.99  ?  969  SER   A O    1 
ATOM   4425 C  CB   . SER   A 1 277 ? 75.790 -13.150 19.813 1.00 16.91  ?  969  SER   A CB   1 
ATOM   4426 O  OG   . SER   A 1 277 ? 74.896 -12.358 20.578 1.00 43.52  ?  969  SER   A OG   1 
ATOM   4427 H  H    . SER   A 1 277 ? 74.103 -15.097 20.199 1.00 21.77  ?  969  SER   A H    1 
ATOM   4428 H  HA   . SER   A 1 277 ? 74.499 -13.097 18.121 1.00 27.88  ?  969  SER   A HA   1 
ATOM   4429 H  HB2  . SER   A 1 277 ? 76.307 -13.856 20.465 1.00 18.91  ?  969  SER   A HB2  1 
ATOM   4430 H  HB3  . SER   A 1 277 ? 76.550 -12.491 19.390 1.00 18.91  ?  969  SER   A HB3  1 
ATOM   4431 H  HG   . SER   A 1 277 ? 74.413 -12.964 21.142 1.00 45.52  ?  969  SER   A HG   1 
ATOM   4432 N  N    . LYS   A 1 278 ? 76.447 -15.747 18.059 1.00 29.43  ?  970  LYS   A N    1 
ATOM   4433 C  CA   . LYS   A 1 278 ? 77.317 -16.481 17.137 1.00 27.56  ?  970  LYS   A CA   1 
ATOM   4434 C  C    . LYS   A 1 278 ? 76.624 -16.732 15.802 1.00 28.01  ?  970  LYS   A C    1 
ATOM   4435 O  O    . LYS   A 1 278 ? 77.193 -16.504 14.736 1.00 35.46  ?  970  LYS   A O    1 
ATOM   4436 C  CB   . LYS   A 1 278 ? 77.720 -17.837 17.696 1.00 33.11  ?  970  LYS   A CB   1 
ATOM   4437 C  CG   . LYS   A 1 278 ? 78.620 -17.856 18.929 1.00 33.74  ?  970  LYS   A CG   1 
ATOM   4438 C  CD   . LYS   A 1 278 ? 78.630 -19.279 19.475 1.00 40.64  ?  970  LYS   A CD   1 
ATOM   4439 C  CE   . LYS   A 1 278 ? 79.459 -19.526 20.716 1.00 51.71  ?  970  LYS   A CE   1 
ATOM   4440 N  NZ   . LYS   A 1 278 ? 79.301 -20.926 21.140 1.00 48.28  1  970  LYS   A NZ   1 
ATOM   4441 H  H    . LYS   A 1 278 ? 76.109 -16.204 18.901 1.00 31.43  ?  970  LYS   A H    1 
ATOM   4442 H  HA   . LYS   A 1 278 ? 78.220 -15.894 16.950 1.00 29.56  ?  970  LYS   A HA   1 
ATOM   4443 H  HB2  . LYS   A 1 278 ? 76.807 -18.396 17.915 1.00 35.11  ?  970  LYS   A HB2  1 
ATOM   4444 H  HB3  . LYS   A 1 278 ? 78.226 -18.412 16.916 1.00 35.11  ?  970  LYS   A HB3  1 
ATOM   4445 H  HG2  . LYS   A 1 278 ? 79.628 -17.529 18.670 1.00 35.74  ?  970  LYS   A HG2  1 
ATOM   4446 H  HG3  . LYS   A 1 278 ? 78.246 -17.169 19.686 1.00 35.74  ?  970  LYS   A HG3  1 
ATOM   4447 H  HD2  . LYS   A 1 278 ? 77.602 -19.565 19.703 1.00 42.64  ?  970  LYS   A HD2  1 
ATOM   4448 H  HD3  . LYS   A 1 278 ? 78.962 -19.963 18.691 1.00 42.64  ?  970  LYS   A HD3  1 
ATOM   4449 H  HE2  . LYS   A 1 278 ? 80.515 -19.324 20.541 1.00 53.71  ?  970  LYS   A HE2  1 
ATOM   4450 H  HE3  . LYS   A 1 278 ? 79.140 -18.875 21.527 1.00 53.71  ?  970  LYS   A HE3  1 
ATOM   4451 H  HZ1  . LYS   A 1 278 ? 79.655 -21.530 20.409 1.00 50.28  ?  970  LYS   A HZ1  1 
ATOM   4452 H  HZ2  . LYS   A 1 278 ? 79.831 -21.088 21.985 1.00 50.28  ?  970  LYS   A HZ2  1 
ATOM   4453 H  HZ3  . LYS   A 1 278 ? 78.319 -21.132 21.296 1.00 50.28  ?  970  LYS   A HZ3  1 
ATOM   4454 N  N    . MET   A 1 279 ? 75.356 -17.130 15.890 1.00 21.35  ?  971  MET   A N    1 
ATOM   4455 C  CA   . MET   A 1 279 ? 74.551 -17.367 14.704 1.00 22.49  ?  971  MET   A CA   1 
ATOM   4456 C  C    . MET   A 1 279 ? 74.285 -16.104 13.901 1.00 31.93  ?  971  MET   A C    1 
ATOM   4457 O  O    . MET   A 1 279 ? 74.261 -16.134 12.670 1.00 33.10  ?  971  MET   A O    1 
ATOM   4458 C  CB   . MET   A 1 279 ? 73.235 -18.067 15.057 1.00 18.86  ?  971  MET   A CB   1 
ATOM   4459 C  CG   . MET   A 1 279 ? 73.444 -19.483 15.604 1.00 23.84  ?  971  MET   A CG   1 
ATOM   4460 S  SD   . MET   A 1 279 ? 71.930 -20.450 15.819 1.00 34.87  ?  971  MET   A SD   1 
ATOM   4461 C  CE   . MET   A 1 279 ? 71.172 -19.568 17.162 1.00 35.04  ?  971  MET   A CE   1 
ATOM   4462 H  H    . MET   A 1 279 ? 74.955 -17.299 16.806 1.00 23.35  ?  971  MET   A H    1 
ATOM   4463 H  HA   . MET   A 1 279 ? 75.128 -18.024 14.057 1.00 24.49  ?  971  MET   A HA   1 
ATOM   4464 H  HB2  . MET   A 1 279 ? 72.674 -17.461 15.768 1.00 20.86  ?  971  MET   A HB2  1 
ATOM   4465 H  HB3  . MET   A 1 279 ? 72.613 -18.136 14.163 1.00 20.86  ?  971  MET   A HB3  1 
ATOM   4466 H  HG2  . MET   A 1 279 ? 74.091 -20.045 14.934 1.00 25.84  ?  971  MET   A HG2  1 
ATOM   4467 H  HG3  . MET   A 1 279 ? 73.971 -19.459 16.557 1.00 25.84  ?  971  MET   A HG3  1 
ATOM   4468 H  HE1  . MET   A 1 279 ? 70.226 -20.034 17.436 1.00 37.04  ?  971  MET   A HE1  1 
ATOM   4469 H  HE2  . MET   A 1 279 ? 71.821 -19.555 18.038 1.00 37.04  ?  971  MET   A HE2  1 
ATOM   4470 H  HE3  . MET   A 1 279 ? 70.964 -18.550 16.848 1.00 37.04  ?  971  MET   A HE3  1 
ATOM   4471 N  N    . ALA   A 1 280 ? 74.164 -14.976 14.591 1.00 30.10  ?  972  ALA   A N    1 
ATOM   4472 C  CA   . ALA   A 1 280 ? 73.943 -13.704 13.916 1.00 34.35  ?  972  ALA   A CA   1 
ATOM   4473 C  C    . ALA   A 1 280 ? 75.142 -13.175 13.139 1.00 29.03  ?  972  ALA   A C    1 
ATOM   4474 O  O    . ALA   A 1 280 ? 74.973 -12.280 12.312 1.00 37.89  ?  972  ALA   A O    1 
ATOM   4475 C  CB   . ALA   A 1 280 ? 73.533 -12.648 14.924 1.00 17.65  ?  972  ALA   A CB   1 
ATOM   4476 H  H    . ALA   A 1 280 ? 74.129 -15.009 15.605 1.00 32.10  ?  972  ALA   A H    1 
ATOM   4477 H  HA   . ALA   A 1 280 ? 73.121 -13.824 13.206 1.00 36.35  ?  972  ALA   A HA   1 
ATOM   4478 H  HB1  . ALA   A 1 280 ? 73.302 -11.698 14.440 1.00 19.65  ?  972  ALA   A HB1  1 
ATOM   4479 H  HB2  . ALA   A 1 280 ? 72.638 -12.949 15.469 1.00 19.65  ?  972  ALA   A HB2  1 
ATOM   4480 H  HB3  . ALA   A 1 280 ? 74.320 -12.462 15.656 1.00 19.65  ?  972  ALA   A HB3  1 
ATOM   4481 N  N    . ARG   A 1 281 ? 76.334 -13.728 13.369 1.00 32.14  ?  973  ARG   A N    1 
ATOM   4482 C  CA   . ARG   A 1 281 ? 77.490 -13.377 12.543 1.00 30.07  ?  973  ARG   A CA   1 
ATOM   4483 C  C    . ARG   A 1 281 ? 77.522 -14.117 11.209 1.00 35.19  ?  973  ARG   A C    1 
ATOM   4484 O  O    . ARG   A 1 281 ? 78.268 -13.719 10.307 1.00 38.28  ?  973  ARG   A O    1 
ATOM   4485 C  CB   . ARG   A 1 281 ? 78.804 -13.722 13.245 1.00 39.85  ?  973  ARG   A CB   1 
ATOM   4486 C  CG   . ARG   A 1 281 ? 79.125 -12.865 14.461 1.00 48.23  ?  973  ARG   A CG   1 
ATOM   4487 C  CD   . ARG   A 1 281 ? 80.547 -13.074 14.976 1.00 67.49  ?  973  ARG   A CD   1 
ATOM   4488 N  NE   . ARG   A 1 281 ? 80.679 -14.381 15.636 1.00 91.53  ?  973  ARG   A NE   1 
ATOM   4489 C  CZ   . ARG   A 1 281 ? 81.178 -15.482 15.043 1.00 104.93 ?  973  ARG   A CZ   1 
ATOM   4490 N  NH1  . ARG   A 1 281 ? 81.616 -15.441 13.777 1.00 106.41 ?  973  ARG   A NH1  1 
ATOM   4491 N  NH2  . ARG   A 1 281 ? 81.232 -16.625 15.723 1.00 102.70 1  973  ARG   A NH2  1 
ATOM   4492 H  H    . ARG   A 1 281 ? 76.414 -14.462 14.065 1.00 34.14  ?  973  ARG   A H    1 
ATOM   4493 H  HA   . ARG   A 1 281 ? 77.487 -12.307 12.323 1.00 32.07  ?  973  ARG   A HA   1 
ATOM   4494 H  HB2  . ARG   A 1 281 ? 78.810 -14.777 13.525 1.00 41.85  ?  973  ARG   A HB2  1 
ATOM   4495 H  HB3  . ARG   A 1 281 ? 79.629 -13.600 12.540 1.00 41.85  ?  973  ARG   A HB3  1 
ATOM   4496 H  HG2  . ARG   A 1 281 ? 78.998 -11.812 14.209 1.00 50.23  ?  973  ARG   A HG2  1 
ATOM   4497 H  HG3  . ARG   A 1 281 ? 78.406 -13.069 15.256 1.00 50.23  ?  973  ARG   A HG3  1 
ATOM   4498 H  HD2  . ARG   A 1 281 ? 81.292 -12.927 14.194 1.00 69.49  ?  973  ARG   A HD2  1 
ATOM   4499 H  HD3  . ARG   A 1 281 ? 80.761 -12.318 15.732 1.00 69.49  ?  973  ARG   A HD3  1 
ATOM   4500 H  HE   . ARG   A 1 281 ? 80.370 -14.444 16.599 1.00 93.53  ?  973  ARG   A HE   1 
ATOM   4501 H  HH11 . ARG   A 1 281 ? 81.577 -14.579 13.257 1.00 108.41 ?  973  ARG   A HH11 1 
ATOM   4502 H  HH12 . ARG   A 1 281 ? 81.993 -16.271 13.344 1.00 108.41 ?  973  ARG   A HH12 1 
ATOM   4503 H  HH21 . ARG   A 1 281 ? 80.911 -16.658 16.683 1.00 104.70 ?  973  ARG   A HH21 1 
ATOM   4504 H  HH22 . ARG   A 1 281 ? 81.596 -17.463 15.289 1.00 104.70 ?  973  ARG   A HH22 1 
ATOM   4505 N  N    . ASP   A 1 282 ? 76.725 -15.174 11.076 1.00 31.19  ?  974  ASP   A N    1 
ATOM   4506 C  CA   . ASP   A 1 282 ? 76.615 -15.912 9.822  1.00 28.77  ?  974  ASP   A CA   1 
ATOM   4507 C  C    . ASP   A 1 282 ? 75.173 -16.347 9.574  1.00 28.44  ?  974  ASP   A C    1 
ATOM   4508 O  O    . ASP   A 1 282 ? 74.877 -17.542 9.638  1.00 29.26  ?  974  ASP   A O    1 
ATOM   4509 C  CB   . ASP   A 1 282 ? 77.678 -17.027 9.735  1.00 31.83  ?  974  ASP   A CB   1 
ATOM   4510 C  CG   . ASP   A 1 282 ? 77.798 -17.685 8.370  1.00 35.43  ?  974  ASP   A CG   1 
ATOM   4511 O  OD1  . ASP   A 1 282 ? 77.219 -17.164 7.397  1.00 43.11  ?  974  ASP   A OD1  1 
ATOM   4512 O  OD2  . ASP   A 1 282 ? 78.479 -18.729 8.259  1.00 54.59  -1 974  ASP   A OD2  1 
ATOM   4513 H  H    . ASP   A 1 282 ? 76.091 -15.423 11.829 1.00 33.19  ?  974  ASP   A H    1 
ATOM   4514 H  HA   . ASP   A 1 282 ? 76.837 -15.225 9.004  1.00 30.77  ?  974  ASP   A HA   1 
ATOM   4515 H  HB2  . ASP   A 1 282 ? 78.660 -16.621 9.978  1.00 33.83  ?  974  ASP   A HB2  1 
ATOM   4516 H  HB3  . ASP   A 1 282 ? 77.472 -17.798 10.478 1.00 33.83  ?  974  ASP   A HB3  1 
ATOM   4517 N  N    . PRO   A 1 283 ? 74.245 -15.414 9.319  1.00 33.31  ?  975  PRO   A N    1 
ATOM   4518 C  CA   . PRO   A 1 283 ? 72.813 -15.705 9.346  1.00 30.82  ?  975  PRO   A CA   1 
ATOM   4519 C  C    . PRO   A 1 283 ? 72.300 -16.810 8.431  1.00 29.35  ?  975  PRO   A C    1 
ATOM   4520 O  O    . PRO   A 1 283 ? 71.452 -17.618 8.829  1.00 25.93  ?  975  PRO   A O    1 
ATOM   4521 C  CB   . PRO   A 1 283 ? 72.162 -14.400 8.947  1.00 28.00  ?  975  PRO   A CB   1 
ATOM   4522 C  CG   . PRO   A 1 283 ? 73.170 -13.317 9.223  1.00 25.68  ?  975  PRO   A CG   1 
ATOM   4523 C  CD   . PRO   A 1 283 ? 74.533 -13.989 9.160  1.00 24.64  ?  975  PRO   A CD   1 
ATOM   4524 H  HA   . PRO   A 1 283 ? 72.554 -15.954 10.375 1.00 32.82  ?  975  PRO   A HA   1 
ATOM   4525 H  HB2  . PRO   A 1 283 ? 71.979 -14.366 7.873  1.00 30.00  ?  975  PRO   A HB2  1 
ATOM   4526 H  HB3  . PRO   A 1 283 ? 71.219 -14.230 9.464  1.00 30.00  ?  975  PRO   A HB3  1 
ATOM   4527 H  HG2  . PRO   A 1 283 ? 73.082 -12.488 8.521  1.00 27.68  ?  975  PRO   A HG2  1 
ATOM   4528 H  HG3  . PRO   A 1 283 ? 73.007 -12.928 10.228 1.00 27.68  ?  975  PRO   A HG3  1 
ATOM   4529 H  HD2  . PRO   A 1 283 ? 75.004 -13.798 8.196  1.00 26.64  ?  975  PRO   A HD2  1 
ATOM   4530 H  HD3  . PRO   A 1 283 ? 75.160 -13.555 9.932  1.00 26.64  ?  975  PRO   A HD3  1 
ATOM   4531 N  N    . GLN   A 1 284 ? 72.839 -16.860 7.212  1.00 32.76  ?  976  GLN   A N    1 
ATOM   4532 C  CA   . GLN   A 1 284 ? 72.366 -17.816 6.215  1.00 32.77  ?  976  GLN   A CA   1 
ATOM   4533 C  C    . GLN   A 1 284 ? 72.725 -19.258 6.532  1.00 22.62  ?  976  GLN   A C    1 
ATOM   4534 O  O    . GLN   A 1 284 ? 72.105 -20.195 6.029  1.00 36.45  ?  976  GLN   A O    1 
ATOM   4535 C  CB   . GLN   A 1 284 ? 72.938 -17.474 4.846  1.00 39.59  ?  976  GLN   A CB   1 
ATOM   4536 C  CG   . GLN   A 1 284 ? 72.398 -16.158 4.269  1.00 53.38  ?  976  GLN   A CG   1 
ATOM   4537 C  CD   . GLN   A 1 284 ? 72.686 -15.913 2.802  1.00 66.38  ?  976  GLN   A CD   1 
ATOM   4538 O  OE1  . GLN   A 1 284 ? 72.101 -15.039 2.172  1.00 86.75  ?  976  GLN   A OE1  1 
ATOM   4539 N  NE2  . GLN   A 1 284 ? 73.589 -16.687 2.235  1.00 84.16  ?  976  GLN   A NE2  1 
ATOM   4540 H  H    . GLN   A 1 284 ? 73.527 -16.172 6.917  1.00 34.76  ?  976  GLN   A H    1 
ATOM   4541 H  HA   . GLN   A 1 284 ? 71.276 -17.763 6.163  1.00 34.77  ?  976  GLN   A HA   1 
ATOM   4542 H  HB2  . GLN   A 1 284 ? 74.028 -17.451 4.888  1.00 41.59  ?  976  GLN   A HB2  1 
ATOM   4543 H  HB3  . GLN   A 1 284 ? 72.678 -18.282 4.156  1.00 41.59  ?  976  GLN   A HB3  1 
ATOM   4544 H  HG2  . GLN   A 1 284 ? 71.317 -16.136 4.382  1.00 55.38  ?  976  GLN   A HG2  1 
ATOM   4545 H  HG3  . GLN   A 1 284 ? 72.786 -15.309 4.832  1.00 55.38  ?  976  GLN   A HG3  1 
ATOM   4546 H  HE21 . GLN   A 1 284 ? 74.060 -17.394 2.779  1.00 86.16  ?  976  GLN   A HE21 1 
ATOM   4547 H  HE22 . GLN   A 1 284 ? 73.813 -16.565 1.260  1.00 86.16  ?  976  GLN   A HE22 1 
ATOM   4548 N  N    . ARG   A 1 285 ? 73.701 -19.435 7.413  1.00 21.42  ?  977  ARG   A N    1 
ATOM   4549 C  CA   . ARG   A 1 285 ? 74.012 -20.759 7.917  1.00 23.42  ?  977  ARG   A CA   1 
ATOM   4550 C  C    . ARG   A 1 285 ? 72.996 -21.273 8.934  1.00 32.09  ?  977  ARG   A C    1 
ATOM   4551 O  O    . ARG   A 1 285 ? 72.985 -22.470 9.234  1.00 31.70  ?  977  ARG   A O    1 
ATOM   4552 C  CB   . ARG   A 1 285 ? 75.411 -20.719 8.524  1.00 21.82  ?  977  ARG   A CB   1 
ATOM   4553 C  CG   . ARG   A 1 285 ? 75.941 -22.061 8.989  1.00 31.87  ?  977  ARG   A CG   1 
ATOM   4554 C  CD   . ARG   A 1 285 ? 77.361 -21.991 9.496  1.00 34.73  ?  977  ARG   A CD   1 
ATOM   4555 N  NE   . ARG   A 1 285 ? 77.688 -23.253 10.174 1.00 28.14  ?  977  ARG   A NE   1 
ATOM   4556 C  CZ   . ARG   A 1 285 ? 78.820 -23.459 10.855 1.00 32.04  ?  977  ARG   A CZ   1 
ATOM   4557 N  NH1  . ARG   A 1 285 ? 79.734 -22.491 10.949 1.00 23.76  ?  977  ARG   A NH1  1 
ATOM   4558 N  NH2  . ARG   A 1 285 ? 79.037 -24.637 11.443 1.00 41.00  1  977  ARG   A NH2  1 
ATOM   4559 H  H    . ARG   A 1 285 ? 74.137 -18.627 7.843  1.00 23.42  ?  977  ARG   A H    1 
ATOM   4560 H  HA   . ARG   A 1 285 ? 74.032 -21.466 7.084  1.00 25.42  ?  977  ARG   A HA   1 
ATOM   4561 H  HB2  . ARG   A 1 285 ? 76.101 -20.318 7.779  1.00 23.82  ?  977  ARG   A HB2  1 
ATOM   4562 H  HB3  . ARG   A 1 285 ? 75.432 -20.022 9.362  1.00 23.82  ?  977  ARG   A HB3  1 
ATOM   4563 H  HG2  . ARG   A 1 285 ? 75.337 -22.447 9.808  1.00 33.87  ?  977  ARG   A HG2  1 
ATOM   4564 H  HG3  . ARG   A 1 285 ? 75.876 -22.787 8.178  1.00 33.87  ?  977  ARG   A HG3  1 
ATOM   4565 H  HD2  . ARG   A 1 285 ? 78.057 -21.805 8.677  1.00 36.73  ?  977  ARG   A HD2  1 
ATOM   4566 H  HD3  . ARG   A 1 285 ? 77.462 -21.172 10.209 1.00 36.73  ?  977  ARG   A HD3  1 
ATOM   4567 H  HE   . ARG   A 1 285 ? 77.005 -24.009 10.104 1.00 30.14  ?  977  ARG   A HE   1 
ATOM   4568 H  HH11 . ARG   A 1 285 ? 79.577 -21.600 10.505 1.00 25.76  ?  977  ARG   A HH11 1 
ATOM   4569 H  HH12 . ARG   A 1 285 ? 80.594 -22.649 11.477 1.00 25.76  ?  977  ARG   A HH12 1 
ATOM   4570 H  HH21 . ARG   A 1 285 ? 78.347 -25.372 11.378 1.00 43.00  ?  977  ARG   A HH21 1 
ATOM   4571 H  HH22 . ARG   A 1 285 ? 79.893 -24.793 11.961 1.00 43.00  ?  977  ARG   A HH22 1 
ATOM   4572 N  N    . TYR   A 1 286 ? 72.132 -20.403 9.455  1.00 27.33  ?  978  TYR   A N    1 
ATOM   4573 C  CA   . TYR   A 1 286 ? 71.283 -20.805 10.580 1.00 27.94  ?  978  TYR   A CA   1 
ATOM   4574 C  C    . TYR   A 1 286 ? 69.807 -20.711 10.278 1.00 33.21  ?  978  TYR   A C    1 
ATOM   4575 O  O    . TYR   A 1 286 ? 69.031 -21.503 10.824 1.00 24.81  ?  978  TYR   A O    1 
ATOM   4576 C  CB   . TYR   A 1 286 ? 71.703 -20.113 11.866 1.00 24.12  ?  978  TYR   A CB   1 
ATOM   4577 C  CG   . TYR   A 1 286 ? 73.118 -20.504 12.239 1.00 15.83  ?  978  TYR   A CG   1 
ATOM   4578 C  CD1  . TYR   A 1 286 ? 73.380 -21.789 12.759 1.00 19.60  ?  978  TYR   A CD1  1 
ATOM   4579 C  CD2  . TYR   A 1 286 ? 74.173 -19.597 12.043 1.00 24.80  ?  978  TYR   A CD2  1 
ATOM   4580 C  CE1  . TYR   A 1 286 ? 74.698 -22.163 13.077 1.00 24.95  ?  978  TYR   A CE1  1 
ATOM   4581 C  CE2  . TYR   A 1 286 ? 75.493 -19.971 12.361 1.00 19.46  ?  978  TYR   A CE2  1 
ATOM   4582 C  CZ   . TYR   A 1 286 ? 75.756 -21.256 12.876 1.00 30.55  ?  978  TYR   A CZ   1 
ATOM   4583 O  OH   . TYR   A 1 286 ? 77.033 -21.620 13.180 1.00 32.46  ?  978  TYR   A OH   1 
ATOM   4584 H  H    . TYR   A 1 286 ? 72.146 -19.431 9.163  1.00 29.33  ?  978  TYR   A H    1 
ATOM   4585 H  HA   . TYR   A 1 286 ? 71.397 -21.866 10.798 1.00 29.94  ?  978  TYR   A HA   1 
ATOM   4586 H  HB2  . TYR   A 1 286 ? 71.627 -19.030 11.758 1.00 26.12  ?  978  TYR   A HB2  1 
ATOM   4587 H  HB3  . TYR   A 1 286 ? 71.041 -20.384 12.688 1.00 26.12  ?  978  TYR   A HB3  1 
ATOM   4588 H  HD1  . TYR   A 1 286 ? 72.572 -22.485 12.907 1.00 21.60  ?  978  TYR   A HD1  1 
ATOM   4589 H  HD2  . TYR   A 1 286 ? 73.974 -18.614 11.644 1.00 26.80  ?  978  TYR   A HD2  1 
ATOM   4590 H  HE1  . TYR   A 1 286 ? 74.899 -23.148 13.476 1.00 26.95  ?  978  TYR   A HE1  1 
ATOM   4591 H  HE2  . TYR   A 1 286 ? 76.301 -19.271 12.206 1.00 21.46  ?  978  TYR   A HE2  1 
ATOM   4592 H  HH   . TYR   A 1 286 ? 77.662 -20.930 13.035 1.00 34.46  ?  978  TYR   A HH   1 
ATOM   4593 N  N    . LEU   A 1 287 ? 69.427 -19.818 9.370  1.00 24.78  ?  979  LEU   A N    1 
ATOM   4594 C  CA   . LEU   A 1 287 ? 68.057 -19.785 8.876  1.00 31.82  ?  979  LEU   A CA   1 
ATOM   4595 C  C    . LEU   A 1 287 ? 68.092 -19.773 7.359  1.00 37.45  ?  979  LEU   A C    1 
ATOM   4596 O  O    . LEU   A 1 287 ? 68.878 -19.032 6.763  1.00 31.97  ?  979  LEU   A O    1 
ATOM   4597 C  CB   . LEU   A 1 287 ? 67.254 -18.593 9.404  1.00 36.26  ?  979  LEU   A CB   1 
ATOM   4598 C  CG   . LEU   A 1 287 ? 67.191 -18.412 10.914 1.00 32.10  ?  979  LEU   A CG   1 
ATOM   4599 C  CD1  . LEU   A 1 287 ? 66.616 -17.055 11.258 1.00 31.27  ?  979  LEU   A CD1  1 
ATOM   4600 C  CD2  . LEU   A 1 287 ? 66.389 -19.507 11.591 1.00 27.68  ?  979  LEU   A CD2  1 
ATOM   4601 H  H    . LEU   A 1 287 ? 70.105 -19.211 8.919  1.00 26.78  ?  979  LEU   A H    1 
ATOM   4602 H  HA   . LEU   A 1 287 ? 67.542 -20.692 9.175  1.00 33.82  ?  979  LEU   A HA   1 
ATOM   4603 H  HB2  . LEU   A 1 287 ? 67.684 -17.697 8.970  1.00 38.26  ?  979  LEU   A HB2  1 
ATOM   4604 H  HB3  . LEU   A 1 287 ? 66.237 -18.647 9.008  1.00 38.26  ?  979  LEU   A HB3  1 
ATOM   4605 H  HG   . LEU   A 1 287 ? 68.204 -18.434 11.317 1.00 34.10  ?  979  LEU   A HG   1 
ATOM   4606 H  HD11 . LEU   A 1 287 ? 66.607 -16.896 12.335 1.00 33.27  ?  979  LEU   A HD11 1 
ATOM   4607 H  HD12 . LEU   A 1 287 ? 67.207 -16.249 10.828 1.00 33.27  ?  979  LEU   A HD12 1 
ATOM   4608 H  HD13 . LEU   A 1 287 ? 65.591 -16.951 10.900 1.00 33.27  ?  979  LEU   A HD13 1 
ATOM   4609 H  HD21 . LEU   A 1 287 ? 66.347 -19.341 12.665 1.00 29.68  ?  979  LEU   A HD21 1 
ATOM   4610 H  HD22 . LEU   A 1 287 ? 65.363 -19.533 11.230 1.00 29.68  ?  979  LEU   A HD22 1 
ATOM   4611 H  HD23 . LEU   A 1 287 ? 66.822 -20.491 11.435 1.00 29.68  ?  979  LEU   A HD23 1 
ATOM   4612 N  N    . VAL   A 1 288 ? 67.213 -20.553 6.748  1.00 33.15  ?  980  VAL   A N    1 
ATOM   4613 C  CA   . VAL   A 1 288 ? 67.154 -20.667 5.300  1.00 37.48  ?  980  VAL   A CA   1 
ATOM   4614 C  C    . VAL   A 1 288 ? 65.852 -20.029 4.819  1.00 34.64  ?  980  VAL   A C    1 
ATOM   4615 O  O    . VAL   A 1 288 ? 64.766 -20.560 5.042  1.00 38.09  ?  980  VAL   A O    1 
ATOM   4616 C  CB   . VAL   A 1 288 ? 67.269 -22.145 4.888  1.00 39.86  ?  980  VAL   A CB   1 
ATOM   4617 C  CG1  . VAL   A 1 288 ? 67.239 -22.315 3.372  1.00 22.93  ?  980  VAL   A CG1  1 
ATOM   4618 C  CG2  . VAL   A 1 288 ? 68.535 -22.797 5.448  1.00 25.96  ?  980  VAL   A CG2  1 
ATOM   4619 H  H    . VAL   A 1 288 ? 66.548 -21.087 7.305  1.00 35.15  ?  980  VAL   A H    1 
ATOM   4620 H  HA   . VAL   A 1 288 ? 67.989 -20.161 4.817  1.00 39.48  ?  980  VAL   A HA   1 
ATOM   4621 H  HB   . VAL   A 1 288 ? 66.415 -22.691 5.295  1.00 41.86  ?  980  VAL   A HB   1 
ATOM   4622 H  HG11 . VAL   A 1 288 ? 67.357 -23.363 3.093  1.00 24.93  ?  980  VAL   A HG11 1 
ATOM   4623 H  HG12 . VAL   A 1 288 ? 66.294 -21.984 2.938  1.00 24.93  ?  980  VAL   A HG12 1 
ATOM   4624 H  HG13 . VAL   A 1 288 ? 68.041 -21.755 2.889  1.00 24.93  ?  980  VAL   A HG13 1 
ATOM   4625 H  HG21 . VAL   A 1 288 ? 68.653 -23.816 5.085  1.00 27.96  ?  980  VAL   A HG21 1 
ATOM   4626 H  HG22 . VAL   A 1 288 ? 69.427 -22.242 5.154  1.00 27.96  ?  980  VAL   A HG22 1 
ATOM   4627 H  HG23 . VAL   A 1 288 ? 68.523 -22.846 6.537  1.00 27.96  ?  980  VAL   A HG23 1 
ATOM   4628 N  N    . ILE   A 1 289 ? 65.967 -18.876 4.178  1.00 30.81  ?  981  ILE   A N    1 
ATOM   4629 C  CA   . ILE   A 1 289 ? 64.825 -18.072 3.755  1.00 37.78  ?  981  ILE   A CA   1 
ATOM   4630 C  C    . ILE   A 1 289 ? 65.011 -17.783 2.267  1.00 45.90  ?  981  ILE   A C    1 
ATOM   4631 O  O    . ILE   A 1 289 ? 66.069 -17.303 1.850  1.00 38.28  ?  981  ILE   A O    1 
ATOM   4632 C  CB   . ILE   A 1 289 ? 64.725 -16.795 4.627  1.00 46.00  ?  981  ILE   A CB   1 
ATOM   4633 C  CG1  . ILE   A 1 289 ? 64.430 -17.102 6.100  1.00 44.23  ?  981  ILE   A CG1  1 
ATOM   4634 C  CG2  . ILE   A 1 289 ? 63.743 -15.746 4.093  1.00 37.69  ?  981  ILE   A CG2  1 
ATOM   4635 C  CD1  . ILE   A 1 289 ? 64.746 -15.958 7.052  1.00 26.00  ?  981  ILE   A CD1  1 
ATOM   4636 H  H    . ILE   A 1 289 ? 66.896 -18.460 4.062  1.00 32.81  ?  981  ILE   A H    1 
ATOM   4637 H  HA   . ILE   A 1 289 ? 63.889 -18.624 3.864  1.00 39.78  ?  981  ILE   A HA   1 
ATOM   4638 H  HB   . ILE   A 1 289 ? 65.711 -16.331 4.599  1.00 48.00  ?  981  ILE   A HB   1 
ATOM   4639 H  HG12 . ILE   A 1 289 ? 63.386 -17.384 6.210  1.00 46.23  ?  981  ILE   A HG12 1 
ATOM   4640 H  HG13 . ILE   A 1 289 ? 65.010 -17.959 6.437  1.00 46.23  ?  981  ILE   A HG13 1 
ATOM   4641 H  HG21 . ILE   A 1 289 ? 63.716 -14.856 4.723  1.00 39.69  ?  981  ILE   A HG21 1 
ATOM   4642 H  HG22 . ILE   A 1 289 ? 64.016 -15.397 3.097  1.00 39.69  ?  981  ILE   A HG22 1 
ATOM   4643 H  HG23 . ILE   A 1 289 ? 62.728 -16.139 4.040  1.00 39.69  ?  981  ILE   A HG23 1 
ATOM   4644 H  HD11 . ILE   A 1 289 ? 64.751 -16.296 8.085  1.00 28.00  ?  981  ILE   A HD11 1 
ATOM   4645 H  HD12 . ILE   A 1 289 ? 65.731 -15.547 6.844  1.00 28.00  ?  981  ILE   A HD12 1 
ATOM   4646 H  HD13 . ILE   A 1 289 ? 64.023 -15.146 6.973  1.00 28.00  ?  981  ILE   A HD13 1 
ATOM   4647 N  N    . GLN   A 1 290 ? 63.987 -18.035 1.452  1.00 55.70  ?  982  GLN   A N    1 
ATOM   4648 C  CA   . GLN   A 1 290 ? 64.085 -17.691 0.029  1.00 65.00  ?  982  GLN   A CA   1 
ATOM   4649 C  C    . GLN   A 1 290 ? 64.105 -16.185 -0.183 1.00 57.26  ?  982  GLN   A C    1 
ATOM   4650 O  O    . GLN   A 1 290 ? 63.207 -15.473 0.266  1.00 69.70  ?  982  GLN   A O    1 
ATOM   4651 C  CB   . GLN   A 1 290 ? 62.917 -18.259 -0.771 1.00 76.93  ?  982  GLN   A CB   1 
ATOM   4652 C  CG   . GLN   A 1 290 ? 63.045 -19.746 -1.086 1.00 90.51  ?  982  GLN   A CG   1 
ATOM   4653 C  CD   . GLN   A 1 290 ? 61.906 -20.245 -1.950 1.00 98.19  ?  982  GLN   A CD   1 
ATOM   4654 O  OE1  . GLN   A 1 290 ? 60.759 -19.828 -1.810 1.00 97.65  ?  982  GLN   A OE1  1 
ATOM   4655 N  NE2  . GLN   A 1 290 ? 62.209 -21.145 -2.856 1.00 102.49 ?  982  GLN   A NE2  1 
ATOM   4656 H  H    . GLN   A 1 290 ? 63.110 -18.364 1.822  1.00 57.70  ?  982  GLN   A H    1 
ATOM   4657 H  HA   . GLN   A 1 290 ? 65.009 -18.116 -0.369 1.00 67.00  ?  982  GLN   A HA   1 
ATOM   4658 H  HB2  . GLN   A 1 290 ? 61.978 -18.056 -0.251 1.00 78.93  ?  982  GLN   A HB2  1 
ATOM   4659 H  HB3  . GLN   A 1 290 ? 62.836 -17.734 -1.727 1.00 78.93  ?  982  GLN   A HB3  1 
ATOM   4660 H  HG2  . GLN   A 1 290 ? 63.994 -19.926 -1.594 1.00 92.51  ?  982  GLN   A HG2  1 
ATOM   4661 H  HG3  . GLN   A 1 290 ? 63.063 -20.327 -0.163 1.00 92.51  ?  982  GLN   A HG3  1 
ATOM   4662 H  HE21 . GLN   A 1 290 ? 63.159 -21.466 -2.954 1.00 104.49 ?  982  GLN   A HE21 1 
ATOM   4663 H  HE22 . GLN   A 1 290 ? 61.489 -21.509 -3.461 1.00 104.49 ?  982  GLN   A HE22 1 
ATOM   4664 N  N    . GLY   A 1 291 ? 65.158 -15.711 -0.834 1.00 55.49  ?  983  GLY   A N    1 
ATOM   4665 C  CA   . GLY   A 1 291 ? 65.250 -14.288 -1.128 1.00 50.32  ?  983  GLY   A CA   1 
ATOM   4666 C  C    . GLY   A 1 291 ? 66.138 -13.517 -0.182 1.00 62.01  ?  983  GLY   A C    1 
ATOM   4667 O  O    . GLY   A 1 291 ? 66.345 -12.320 -0.375 1.00 66.63  ?  983  GLY   A O    1 
ATOM   4668 H  H    . GLY   A 1 291 ? 65.897 -16.331 -1.130 1.00 57.49  ?  983  GLY   A H    1 
ATOM   4669 H  HA2  . GLY   A 1 291 ? 65.683 -14.190 -2.124 1.00 52.32  ?  983  GLY   A HA2  1 
ATOM   4670 H  HA3  . GLY   A 1 291 ? 64.278 -13.795 -1.182 1.00 52.32  ?  983  GLY   A HA3  1 
ATOM   4671 N  N    . ASP   A 1 292 ? 66.650 -14.208 0.835  1.00 67.50  ?  984  ASP   A N    1 
ATOM   4672 C  CA   . ASP   A 1 292 ? 67.356 -13.621 1.973  1.00 68.73  ?  984  ASP   A CA   1 
ATOM   4673 C  C    . ASP   A 1 292 ? 68.438 -12.591 1.670  1.00 77.95  ?  984  ASP   A C    1 
ATOM   4674 O  O    . ASP   A 1 292 ? 68.535 -11.539 2.307  1.00 78.45  ?  984  ASP   A O    1 
ATOM   4675 C  CB   . ASP   A 1 292 ? 67.858 -14.748 2.864  1.00 61.85  ?  984  ASP   A CB   1 
ATOM   4676 C  CG   . ASP   A 1 292 ? 68.261 -14.342 4.257  1.00 53.59  ?  984  ASP   A CG   1 
ATOM   4677 O  OD1  . ASP   A 1 292 ? 67.733 -13.340 4.777  1.00 45.95  ?  984  ASP   A OD1  1 
ATOM   4678 O  OD2  . ASP   A 1 292 ? 69.103 -15.033 4.857  1.00 55.50  -1 984  ASP   A OD2  1 
ATOM   4679 H  H    . ASP   A 1 292 ? 66.399 -15.187 0.910  1.00 69.50  ?  984  ASP   A H    1 
ATOM   4680 H  HA   . ASP   A 1 292 ? 66.579 -13.093 2.524  1.00 70.73  ?  984  ASP   A HA   1 
ATOM   4681 H  HB2  . ASP   A 1 292 ? 67.058 -15.462 3.017  1.00 63.85  ?  984  ASP   A HB2  1 
ATOM   4682 H  HB3  . ASP   A 1 292 ? 68.676 -15.289 2.386  1.00 63.85  ?  984  ASP   A HB3  1 
ATOM   4683 N  N    . GLU   A 1 293 ? 69.199 -12.894 0.630  1.00 87.59  ?  985  GLU   A N    1 
ATOM   4684 C  CA   . GLU   A 1 293 ? 70.208 -12.001 0.073  1.00 102.29 ?  985  GLU   A CA   1 
ATOM   4685 C  C    . GLU   A 1 293 ? 69.727 -10.591 -0.330 1.00 106.68 ?  985  GLU   A C    1 
ATOM   4686 O  O    . GLU   A 1 293 ? 70.538 -9.674  -0.471 1.00 107.81 ?  985  GLU   A O    1 
ATOM   4687 C  CB   . GLU   A 1 293 ? 70.996 -12.797 -0.998 1.00 104.27 ?  985  GLU   A CB   1 
ATOM   4688 C  CG   . GLU   A 1 293 ? 71.290 -12.205 -2.390 1.00 118.87 ?  985  GLU   A CG   1 
ATOM   4689 C  CD   . GLU   A 1 293 ? 70.042 -12.229 -3.264 1.00 127.75 ?  985  GLU   A CD   1 
ATOM   4690 O  OE1  . GLU   A 1 293 ? 69.113 -13.018 -2.982 1.00 130.07 ?  985  GLU   A OE1  1 
ATOM   4691 O  OE2  . GLU   A 1 293 ? 69.980 -11.455 -4.244 1.00 128.76 -1 985  GLU   A OE2  1 
ATOM   4692 H  H    . GLU   A 1 293 ? 69.034 -13.773 0.166  1.00 89.59  ?  985  GLU   A H    1 
ATOM   4693 H  HA   . GLU   A 1 293 ? 70.910 -11.817 0.890  1.00 104.29 ?  985  GLU   A HA   1 
ATOM   4694 H  HB2  . GLU   A 1 293 ? 71.962 -13.038 -0.562 1.00 106.27 ?  985  GLU   A HB2  1 
ATOM   4695 H  HB3  . GLU   A 1 293 ? 70.566 -13.791 -1.133 1.00 106.27 ?  985  GLU   A HB3  1 
ATOM   4696 H  HG2  . GLU   A 1 293 ? 71.672 -11.187 -2.311 1.00 120.87 ?  985  GLU   A HG2  1 
ATOM   4697 H  HG3  . GLU   A 1 293 ? 72.062 -12.795 -2.886 1.00 120.87 ?  985  GLU   A HG3  1 
ATOM   4698 N  N    . ARG   A 1 294 ? 68.415 -10.410 -0.490 1.00 107.08 ?  986  ARG   A N    1 
ATOM   4699 C  CA   . ARG   A 1 294 ? 67.848 -9.242  -1.158 1.00 106.44 ?  986  ARG   A CA   1 
ATOM   4700 C  C    . ARG   A 1 294 ? 66.873 -8.444  -0.285 1.00 101.98 ?  986  ARG   A C    1 
ATOM   4701 O  O    . ARG   A 1 294 ? 66.156 -7.581  -0.793 1.00 95.83  ?  986  ARG   A O    1 
ATOM   4702 C  CB   . ARG   A 1 294 ? 67.194 -9.708  -2.466 1.00 110.98 ?  986  ARG   A CB   1 
ATOM   4703 C  CG   . ARG   A 1 294 ? 67.130 -8.666  -3.582 1.00 120.21 ?  986  ARG   A CG   1 
ATOM   4704 C  CD   . ARG   A 1 294 ? 66.339 -9.140  -4.795 1.00 125.40 ?  986  ARG   A CD   1 
ATOM   4705 N  NE   . ARG   A 1 294 ? 64.890 -8.954  -4.595 1.00 124.29 ?  986  ARG   A NE   1 
ATOM   4706 C  CZ   . ARG   A 1 294 ? 63.952 -9.413  -5.443 1.00 122.67 ?  986  ARG   A CZ   1 
ATOM   4707 N  NH1  . ARG   A 1 294 ? 64.304 -10.089 -6.545 1.00 123.47 ?  986  ARG   A NH1  1 
ATOM   4708 N  NH2  . ARG   A 1 294 ? 62.659 -9.192  -5.185 1.00 116.28 1  986  ARG   A NH2  1 
ATOM   4709 H  H    . ARG   A 1 294 ? 67.792 -11.196 -0.313 1.00 109.08 ?  986  ARG   A H    1 
ATOM   4710 H  HA   . ARG   A 1 294 ? 68.639 -8.537  -1.422 1.00 108.44 ?  986  ARG   A HA   1 
ATOM   4711 H  HB2  . ARG   A 1 294 ? 67.737 -10.567 -2.857 1.00 112.98 ?  986  ARG   A HB2  1 
ATOM   4712 H  HB3  . ARG   A 1 294 ? 66.191 -10.083 -2.249 1.00 112.98 ?  986  ARG   A HB3  1 
ATOM   4713 H  HG2  . ARG   A 1 294 ? 66.707 -7.729  -3.222 1.00 122.21 ?  986  ARG   A HG2  1 
ATOM   4714 H  HG3  . ARG   A 1 294 ? 68.147 -8.425  -3.895 1.00 122.21 ?  986  ARG   A HG3  1 
ATOM   4715 H  HD2  . ARG   A 1 294 ? 66.631 -8.559  -5.670 1.00 127.40 ?  986  ARG   A HD2  1 
ATOM   4716 H  HD3  . ARG   A 1 294 ? 66.566 -10.182 -5.017 1.00 127.40 ?  986  ARG   A HD3  1 
ATOM   4717 H  HE   . ARG   A 1 294 ? 64.601 -8.447  -3.769 1.00 126.29 ?  986  ARG   A HE   1 
ATOM   4718 H  HH11 . ARG   A 1 294 ? 65.277 -10.257 -6.748 1.00 125.47 ?  986  ARG   A HH11 1 
ATOM   4719 H  HH12 . ARG   A 1 294 ? 63.596 -10.432 -7.177 1.00 125.47 ?  986  ARG   A HH12 1 
ATOM   4720 H  HH21 . ARG   A 1 294 ? 62.388 -8.685  -4.356 1.00 118.28 ?  986  ARG   A HH21 1 
ATOM   4721 H  HH22 . ARG   A 1 294 ? 61.949 -9.530  -5.819 1.00 118.28 ?  986  ARG   A HH22 1 
ATOM   4722 N  N    . MET   A 1 295 ? 66.812 -8.735  1.012  1.00 101.90 ?  987  MET   A N    1 
ATOM   4723 C  CA   . MET   A 1 295 ? 65.777 -8.138  1.872  1.00 98.46  ?  987  MET   A CA   1 
ATOM   4724 C  C    . MET   A 1 295 ? 66.117 -6.706  2.296  1.00 97.71  ?  987  MET   A C    1 
ATOM   4725 O  O    . MET   A 1 295 ? 67.292 -6.371  2.470  1.00 91.23  ?  987  MET   A O    1 
ATOM   4726 C  CB   . MET   A 1 295 ? 65.616 -8.962  3.151  1.00 95.43  ?  987  MET   A CB   1 
ATOM   4727 C  CG   . MET   A 1 295 ? 65.304 -10.439 2.947  1.00 70.80  ?  987  MET   A CG   1 
ATOM   4728 S  SD   . MET   A 1 295 ? 63.777 -10.728 2.063  1.00 80.78  ?  987  MET   A SD   1 
ATOM   4729 C  CE   . MET   A 1 295 ? 63.334 -12.376 2.607  1.00 61.34  ?  987  MET   A CE   1 
ATOM   4730 H  H    . MET   A 1 295 ? 67.451 -9.420  1.393  1.00 103.90 ?  987  MET   A H    1 
ATOM   4731 H  HA   . MET   A 1 295 ? 64.822 -8.126  1.339  1.00 100.46 ?  987  MET   A HA   1 
ATOM   4732 H  HB2  . MET   A 1 295 ? 66.527 -8.891  3.748  1.00 97.43  ?  987  MET   A HB2  1 
ATOM   4733 H  HB3  . MET   A 1 295 ? 64.830 -8.524  3.765  1.00 97.43  ?  987  MET   A HB3  1 
ATOM   4734 H  HG2  . MET   A 1 295 ? 66.103 -10.927 2.400  1.00 72.80  ?  987  MET   A HG2  1 
ATOM   4735 H  HG3  . MET   A 1 295 ? 65.235 -10.931 3.914  1.00 72.80  ?  987  MET   A HG3  1 
ATOM   4736 H  HE1  . MET   A 1 295 ? 62.565 -12.790 1.955  1.00 63.34  ?  987  MET   A HE1  1 
ATOM   4737 H  HE2  . MET   A 1 295 ? 64.196 -13.041 2.585  1.00 63.34  ?  987  MET   A HE2  1 
ATOM   4738 H  HE3  . MET   A 1 295 ? 62.935 -12.348 3.619  1.00 63.34  ?  987  MET   A HE3  1 
ATOM   4739 N  N    . HIS   A 1 296 ? 65.097 -5.870  2.500  1.00 100.43 ?  988  HIS   A N    1 
ATOM   4740 C  CA   . HIS   A 1 296 ? 65.323 -4.484  2.924  1.00 104.74 ?  988  HIS   A CA   1 
ATOM   4741 C  C    . HIS   A 1 296 ? 64.177 -3.938  3.770  1.00 105.28 ?  988  HIS   A C    1 
ATOM   4742 O  O    . HIS   A 1 296 ? 63.123 -3.574  3.241  1.00 102.88 ?  988  HIS   A O    1 
ATOM   4743 C  CB   . HIS   A 1 296 ? 65.709 -3.565  1.759  1.00 107.84 ?  988  HIS   A CB   1 
ATOM   4744 C  CG   . HIS   A 1 296 ? 65.621 -2.077  2.039  1.00 107.91 ?  988  HIS   A CG   1 
ATOM   4745 N  ND1  . HIS   A 1 296 ? 66.329 -1.450  3.062  1.00 110.08 ?  988  HIS   A ND1  1 
ATOM   4746 C  CD2  . HIS   A 1 296 ? 64.887 -1.057  1.434  1.00 106.63 ?  988  HIS   A CD2  1 
ATOM   4747 C  CE1  . HIS   A 1 296 ? 66.007 -0.172  3.039  1.00 106.80 ?  988  HIS   A CE1  1 
ATOM   4748 N  NE2  . HIS   A 1 296 ? 65.154 0.152   2.097  1.00 108.30 ?  988  HIS   A NE2  1 
ATOM   4749 H  H    . HIS   A 1 296 ? 64.133 -6.185  2.392  1.00 102.43 ?  988  HIS   A H    1 
ATOM   4750 H  HA   . HIS   A 1 296 ? 66.187 -4.474  3.592  1.00 106.74 ?  988  HIS   A HA   1 
ATOM   4751 H  HB2  . HIS   A 1 296 ? 66.720 -3.795  1.421  1.00 109.84 ?  988  HIS   A HB2  1 
ATOM   4752 H  HB3  . HIS   A 1 296 ? 65.053 -3.769  0.912  1.00 109.84 ?  988  HIS   A HB3  1 
ATOM   4753 H  HD1  . HIS   A 1 296 ? 66.961 -1.890  3.717  1.00 112.08 ?  988  HIS   A HD1  1 
ATOM   4754 H  HD2  . HIS   A 1 296 ? 64.201 -1.105  0.599  1.00 108.63 ?  988  HIS   A HD2  1 
ATOM   4755 H  HE1  . HIS   A 1 296 ? 66.412 0.548   3.737  1.00 108.80 ?  988  HIS   A HE1  1 
ATOM   4756 N  N    . LEU   A 1 297 ? 64.416 -3.827  5.075  1.00 104.64 ?  989  LEU   A N    1 
ATOM   4757 C  CA   . LEU   A 1 297 ? 63.487 -3.153  5.985  1.00 98.38  ?  989  LEU   A CA   1 
ATOM   4758 C  C    . LEU   A 1 297 ? 63.969 -1.721  6.263  1.00 99.56  ?  989  LEU   A C    1 
ATOM   4759 O  O    . LEU   A 1 297 ? 65.170 -1.450  6.135  1.00 89.57  ?  989  LEU   A O    1 
ATOM   4760 C  CB   . LEU   A 1 297 ? 63.437 -3.914  7.313  1.00 87.73  ?  989  LEU   A CB   1 
ATOM   4761 C  CG   . LEU   A 1 297 ? 62.941 -5.356  7.221  1.00 82.11  ?  989  LEU   A CG   1 
ATOM   4762 C  CD1  . LEU   A 1 297 ? 62.998 -6.021  8.581  1.00 74.70  ?  989  LEU   A CD1  1 
ATOM   4763 C  CD2  . LEU   A 1 297 ? 61.537 -5.467  6.650  1.00 71.37  ?  989  LEU   A CD2  1 
ATOM   4764 H  H    . LEU   A 1 297 ? 65.328 -4.056  5.433  1.00 106.64 ?  989  LEU   A H    1 
ATOM   4765 H  HA   . LEU   A 1 297 ? 62.490 -3.114  5.552  1.00 100.38 ?  989  LEU   A HA   1 
ATOM   4766 H  HB2  . LEU   A 1 297 ? 64.435 -3.911  7.754  1.00 89.73  ?  989  LEU   A HB2  1 
ATOM   4767 H  HB3  . LEU   A 1 297 ? 62.818 -3.384  8.035  1.00 89.73  ?  989  LEU   A HB3  1 
ATOM   4768 H  HG   . LEU   A 1 297 ? 63.613 -5.910  6.564  1.00 84.11  ?  989  LEU   A HG   1 
ATOM   4769 H  HD11 . LEU   A 1 297 ? 62.822 -7.092  8.507  1.00 76.70  ?  989  LEU   A HD11 1 
ATOM   4770 H  HD12 . LEU   A 1 297 ? 63.972 -5.886  9.039  1.00 76.70  ?  989  LEU   A HD12 1 
ATOM   4771 H  HD13 . LEU   A 1 297 ? 62.264 -5.599  9.264  1.00 76.70  ?  989  LEU   A HD13 1 
ATOM   4772 H  HD21 . LEU   A 1 297 ? 61.190 -6.500  6.656  1.00 73.37  ?  989  LEU   A HD21 1 
ATOM   4773 H  HD22 . LEU   A 1 297 ? 60.816 -4.875  7.211  1.00 73.37  ?  989  LEU   A HD22 1 
ATOM   4774 H  HD23 . LEU   A 1 297 ? 61.509 -5.132  5.618  1.00 73.37  ?  989  LEU   A HD23 1 
ATOM   4775 N  N    . PRO   A 1 298 ? 63.074 -0.793  6.655  1.00 104.77 ?  990  PRO   A N    1 
ATOM   4776 C  CA   . PRO   A 1 298 ? 63.438 0.604   6.892  1.00 106.31 ?  990  PRO   A CA   1 
ATOM   4777 C  C    . PRO   A 1 298 ? 64.202 0.862   8.185  1.00 107.88 ?  990  PRO   A C    1 
ATOM   4778 O  O    . PRO   A 1 298 ? 64.444 -0.020  9.005  1.00 106.01 ?  990  PRO   A O    1 
ATOM   4779 C  CB   . PRO   A 1 298 ? 62.104 1.348   6.888  1.00 98.45  ?  990  PRO   A CB   1 
ATOM   4780 C  CG   . PRO   A 1 298 ? 61.072 0.307   7.316  1.00 94.81  ?  990  PRO   A CG   1 
ATOM   4781 C  CD   . PRO   A 1 298 ? 61.631 -1.023  6.802  1.00 100.25 ?  990  PRO   A CD   1 
ATOM   4782 H  HA   . PRO   A 1 298 ? 64.056 0.963   6.066  1.00 108.31 ?  990  PRO   A HA   1 
ATOM   4783 H  HB2  . PRO   A 1 298 ? 62.067 2.237   7.521  1.00 100.45 ?  990  PRO   A HB2  1 
ATOM   4784 H  HB3  . PRO   A 1 298 ? 61.883 1.679   5.873  1.00 100.45 ?  990  PRO   A HB3  1 
ATOM   4785 H  HG2  . PRO   A 1 298 ? 61.016 0.285   8.406  1.00 96.81  ?  990  PRO   A HG2  1 
ATOM   4786 H  HG3  . PRO   A 1 298 ? 60.072 0.523   6.939  1.00 96.81  ?  990  PRO   A HG3  1 
ATOM   4787 H  HD2  . PRO   A 1 298 ? 61.384 -1.838  7.481  1.00 102.25 ?  990  PRO   A HD2  1 
ATOM   4788 H  HD3  . PRO   A 1 298 ? 61.200 -1.248  5.825  1.00 102.25 ?  990  PRO   A HD3  1 
ATOM   4789 N  N    . SER   A 1 299 ? 64.550 2.124   8.365  1.00 115.77 ?  991  SER   A N    1 
ATOM   4790 C  CA   . SER   A 1 299 ? 65.107 2.631   9.611  1.00 125.26 ?  991  SER   A CA   1 
ATOM   4791 C  C    . SER   A 1 299 ? 64.530 3.983   10.036 1.00 135.89 ?  991  SER   A C    1 
ATOM   4792 O  O    . SER   A 1 299 ? 64.223 4.132   11.222 1.00 137.05 ?  991  SER   A O    1 
ATOM   4793 C  CB   . SER   A 1 299 ? 66.626 2.472   9.713  1.00 119.61 ?  991  SER   A CB   1 
ATOM   4794 O  OG   . SER   A 1 299 ? 67.367 3.292   8.820  1.00 116.93 ?  991  SER   A OG   1 
ATOM   4795 H  H    . SER   A 1 299 ? 64.347 2.794   7.643  1.00 117.77 ?  991  SER   A H    1 
ATOM   4796 H  HA   . SER   A 1 299 ? 64.731 1.975   10.401 1.00 127.26 ?  991  SER   A HA   1 
ATOM   4797 H  HB2  . SER   A 1 299 ? 66.952 2.693   10.731 1.00 121.61 ?  991  SER   A HB2  1 
ATOM   4798 H  HB3  . SER   A 1 299 ? 66.905 1.435   9.527  1.00 121.61 ?  991  SER   A HB3  1 
ATOM   4799 H  HG   . SER   A 1 299 ? 67.302 4.194   9.104  1.00 118.93 ?  991  SER   A HG   1 
ATOM   4800 N  N    . PRO   A 1 300 ? 64.337 4.978   9.141  1.00 145.57 ?  992  PRO   A N    1 
ATOM   4801 C  CA   . PRO   A 1 300 ? 63.707 6.237   9.533  1.00 152.98 ?  992  PRO   A CA   1 
ATOM   4802 C  C    . PRO   A 1 300 ? 62.185 6.131   9.596  1.00 159.43 ?  992  PRO   A C    1 
ATOM   4803 O  O    . PRO   A 1 300 ? 61.596 5.065   9.401  1.00 161.32 ?  992  PRO   A O    1 
ATOM   4804 C  CB   . PRO   A 1 300 ? 64.163 7.226   8.468  1.00 152.12 ?  992  PRO   A CB   1 
ATOM   4805 C  CG   . PRO   A 1 300 ? 64.332 6.382   7.213  1.00 149.46 ?  992  PRO   A CG   1 
ATOM   4806 C  CD   . PRO   A 1 300 ? 64.784 5.018   7.739  1.00 147.07 ?  992  PRO   A CD   1 
ATOM   4807 H  HA   . PRO   A 1 300 ? 64.065 6.568   10.510 1.00 154.98 ?  992  PRO   A HA   1 
ATOM   4808 H  HB2  . PRO   A 1 300 ? 63.490 8.069   8.310  1.00 154.12 ?  992  PRO   A HB2  1 
ATOM   4809 H  HB3  . PRO   A 1 300 ? 65.130 7.642   8.756  1.00 154.12 ?  992  PRO   A HB3  1 
ATOM   4810 H  HG2  . PRO   A 1 300 ? 63.369 6.285   6.710  1.00 151.46 ?  992  PRO   A HG2  1 
ATOM   4811 H  HG3  . PRO   A 1 300 ? 65.035 6.811   6.500  1.00 151.46 ?  992  PRO   A HG3  1 
ATOM   4812 H  HD2  . PRO   A 1 300 ? 64.337 4.250   7.112  1.00 149.07 ?  992  PRO   A HD2  1 
ATOM   4813 H  HD3  . PRO   A 1 300 ? 65.867 4.941   7.673  1.00 149.07 ?  992  PRO   A HD3  1 
ATOM   4814 N  N    . THR   A 1 301 ? 61.558 7.268   9.862  1.00 166.44 ?  993  THR   A N    1 
ATOM   4815 C  CA   . THR   A 1 301 ? 60.109 7.372   9.993  1.00 171.96 ?  993  THR   A CA   1 
ATOM   4816 C  C    . THR   A 1 301 ? 59.600 8.597   9.234  1.00 174.53 ?  993  THR   A C    1 
ATOM   4817 O  O    . THR   A 1 301 ? 60.363 9.312   8.578  1.00 175.15 ?  993  THR   A O    1 
ATOM   4818 C  CB   . THR   A 1 301 ? 59.640 7.248   11.463 1.00 171.00 ?  993  THR   A CB   1 
ATOM   4819 O  OG1  . THR   A 1 301 ? 60.178 8.259   12.308 1.00 170.79 ?  993  THR   A OG1  1 
ATOM   4820 C  CG2  . THR   A 1 301 ? 59.911 5.900   12.105 1.00 170.91 ?  993  THR   A CG2  1 
ATOM   4821 H  H    . THR   A 1 301 ? 62.076 8.128   9.950  1.00 168.44 ?  993  THR   A H    1 
ATOM   4822 H  HA   . THR   A 1 301 ? 59.647 6.544   9.450  1.00 173.96 ?  993  THR   A HA   1 
ATOM   4823 H  HB   . THR   A 1 301 ? 58.557 7.378   11.489 1.00 173.00 ?  993  THR   A HB   1 
ATOM   4824 H  HG1  . THR   A 1 301 ? 59.976 9.110   11.942 1.00 172.79 ?  993  THR   A HG1  1 
ATOM   4825 H  HG21 . THR   A 1 301 ? 59.454 5.836   13.093 1.00 172.91 ?  993  THR   A HG21 1 
ATOM   4826 H  HG22 . THR   A 1 301 ? 59.493 5.093   11.501 1.00 172.91 ?  993  THR   A HG22 1 
ATOM   4827 H  HG23 . THR   A 1 301 ? 60.977 5.709   12.222 1.00 172.91 ?  993  THR   A HG23 1 
ATOM   4828 N  N    . ASP   A 1 302 ? 58.291 8.812   9.318  1.00 176.41 ?  994  ASP   A N    1 
ATOM   4829 C  CA   . ASP   A 1 302 ? 57.609 9.962   8.735  1.00 176.72 ?  994  ASP   A CA   1 
ATOM   4830 C  C    . ASP   A 1 302 ? 57.829 11.225  9.583  1.00 177.68 ?  994  ASP   A C    1 
ATOM   4831 O  O    . ASP   A 1 302 ? 58.913 11.805  9.570  1.00 178.06 ?  994  ASP   A O    1 
ATOM   4832 C  CB   . ASP   A 1 302 ? 56.115 9.633   8.506  1.00 176.68 ?  994  ASP   A CB   1 
ATOM   4833 C  CG   . ASP   A 1 302 ? 55.381 9.057   9.708  1.00 177.35 ?  994  ASP   A CG   1 
ATOM   4834 O  OD1  . ASP   A 1 302 ? 55.621 7.884   10.056 1.00 179.19 ?  994  ASP   A OD1  1 
ATOM   4835 O  OD2  . ASP   A 1 302 ? 54.568 9.781   10.319 1.00 175.04 -1 994  ASP   A OD2  1 
ATOM   4836 H  H    . ASP   A 1 302 ? 57.710 8.163   9.832  1.00 178.41 ?  994  ASP   A H    1 
ATOM   4837 H  HA   . ASP   A 1 302 ? 58.045 10.171  7.755  1.00 178.72 ?  994  ASP   A HA   1 
ATOM   4838 H  HB2  . ASP   A 1 302 ? 55.580 10.509  8.134  1.00 178.68 ?  994  ASP   A HB2  1 
ATOM   4839 H  HB3  . ASP   A 1 302 ? 56.039 8.896   7.705  1.00 178.68 ?  994  ASP   A HB3  1 
ATOM   4840 N  N    . SER   A 1 303 ? 56.802 11.653  10.309 1.00 177.81 ?  995  SER   A N    1 
ATOM   4841 C  CA   . SER   A 1 303 ? 56.804 12.772  11.259 1.00 176.83 ?  995  SER   A CA   1 
ATOM   4842 C  C    . SER   A 1 303 ? 56.447 14.108  10.596 1.00 176.11 ?  995  SER   A C    1 
ATOM   4843 O  O    . SER   A 1 303 ? 55.644 14.907  11.075 1.00 173.91 ?  995  SER   A O    1 
ATOM   4844 C  CB   . SER   A 1 303 ? 58.004 12.808  12.240 1.00 175.82 ?  995  SER   A CB   1 
ATOM   4845 O  OG   . SER   A 1 303 ? 59.152 13.419  11.683 1.00 173.85 ?  995  SER   A OG   1 
ATOM   4846 H  H    . SER   A 1 303 ? 55.947 11.109  10.248 1.00 179.81 ?  995  SER   A H    1 
ATOM   4847 H  HA   . SER   A 1 303 ? 55.949 12.529  11.891 1.00 178.83 ?  995  SER   A HA   1 
ATOM   4848 H  HB2  . SER   A 1 303 ? 57.728 13.366  13.135 1.00 177.82 ?  995  SER   A HB2  1 
ATOM   4849 H  HB3  . SER   A 1 303 ? 58.252 11.800  12.576 1.00 177.82 ?  995  SER   A HB3  1 
ATOM   4850 H  HG   . SER   A 1 303 ? 59.339 12.939  10.873 1.00 175.85 ?  995  SER   A HG   1 
ATOM   4851 N  N    . GLU   A 1 313 ? 53.445 19.168  11.254 1.00 98.47  1  1005 GLU   A N    1 
ATOM   4852 C  CA   . GLU   A 1 313 ? 54.528 18.206  10.973 1.00 99.23  ?  1005 GLU   A CA   1 
ATOM   4853 C  C    . GLU   A 1 313 ? 55.925 18.819  11.039 1.00 102.07 ?  1005 GLU   A C    1 
ATOM   4854 O  O    . GLU   A 1 313 ? 56.880 18.241  10.515 1.00 103.33 ?  1005 GLU   A O    1 
ATOM   4855 C  CB   . GLU   A 1 313 ? 54.255 17.505  9.653  1.00 94.36  ?  1005 GLU   A CB   1 
ATOM   4856 H  H    . GLU   A 1 313 ? 52.554 18.696  11.202 1.00 100.47 ?  1005 GLU   A H    1 
ATOM   4857 H  HA   . GLU   A 1 313 ? 54.489 17.456  11.764 1.00 101.23 ?  1005 GLU   A HA   1 
ATOM   4858 H  HB2  . GLU   A 1 313 ? 53.326 16.936  9.696  1.00 96.36  ?  1005 GLU   A HB2  1 
ATOM   4859 H  HB3  . GLU   A 1 313 ? 54.171 18.219  8.833  1.00 96.36  ?  1005 GLU   A HB3  1 
ATOM   4860 H  HB1  . GLU   A 1 313 ? 55.047 16.804  9.389  1.00 96.36  ?  1005 GLU   A HB1  1 
ATOM   4861 N  N    . ASP   A 1 314 ? 56.069 19.972  11.695 1.00 100.39 ?  1006 ASP   A N    1 
ATOM   4862 C  CA   . ASP   A 1 314 ? 57.395 20.550  11.921 1.00 99.83  ?  1006 ASP   A CA   1 
ATOM   4863 C  C    . ASP   A 1 314 ? 57.946 19.979  13.228 1.00 96.91  ?  1006 ASP   A C    1 
ATOM   4864 O  O    . ASP   A 1 314 ? 57.299 20.015  14.279 1.00 96.84  ?  1006 ASP   A O    1 
ATOM   4865 C  CB   . ASP   A 1 314 ? 57.279 22.079  11.938 1.00 105.59 ?  1006 ASP   A CB   1 
ATOM   4866 C  CG   . ASP   A 1 314 ? 58.519 22.874  12.315 1.00 112.36 ?  1006 ASP   A CG   1 
ATOM   4867 O  OD1  . ASP   A 1 314 ? 59.628 22.300  12.351 1.00 110.90 ?  1006 ASP   A OD1  1 
ATOM   4868 O  OD2  . ASP   A 1 314 ? 58.391 24.086  12.583 1.00 123.02 -1 1006 ASP   A OD2  1 
ATOM   4869 H  H    . ASP   A 1 314 ? 55.289 20.387  12.177 1.00 102.39 ?  1006 ASP   A H    1 
ATOM   4870 H  HA   . ASP   A 1 314 ? 58.070 20.297  11.099 1.00 101.83 ?  1006 ASP   A HA   1 
ATOM   4871 H  HB2  . ASP   A 1 314 ? 56.974 22.420  10.948 1.00 107.59 ?  1006 ASP   A HB2  1 
ATOM   4872 H  HB3  . ASP   A 1 314 ? 56.482 22.390  12.608 1.00 107.59 ?  1006 ASP   A HB3  1 
ATOM   4873 N  N    . MET   A 1 315 ? 59.139 19.409  13.118 1.00 91.44  ?  1007 MET   A N    1 
ATOM   4874 C  CA   . MET   A 1 315 ? 59.633 18.416  14.065 1.00 81.17  ?  1007 MET   A CA   1 
ATOM   4875 C  C    . MET   A 1 315 ? 61.077 18.680  14.481 1.00 80.33  ?  1007 MET   A C    1 
ATOM   4876 O  O    . MET   A 1 315 ? 61.812 17.761  14.846 1.00 70.08  ?  1007 MET   A O    1 
ATOM   4877 C  CB   . MET   A 1 315 ? 59.409 16.993  13.535 1.00 88.58  ?  1007 MET   A CB   1 
ATOM   4878 C  CG   . MET   A 1 315 ? 57.962 16.540  13.323 1.00 94.74  ?  1007 MET   A CG   1 
ATOM   4879 S  SD   . MET   A 1 315 ? 57.133 15.767  14.733 1.00 121.00 ?  1007 MET   A SD   1 
ATOM   4880 C  CE   . MET   A 1 315 ? 56.452 17.185  15.583 1.00 97.51  ?  1007 MET   A CE   1 
ATOM   4881 H  H    . MET   A 1 315 ? 59.621 19.495  12.234 1.00 93.44  ?  1007 MET   A H    1 
ATOM   4882 H  HA   . MET   A 1 315 ? 59.089 18.496  15.005 1.00 83.17  ?  1007 MET   A HA   1 
ATOM   4883 H  HB2  . MET   A 1 315 ? 59.913 16.929  12.569 1.00 90.58  ?  1007 MET   A HB2  1 
ATOM   4884 H  HB3  . MET   A 1 315 ? 59.916 16.250  14.150 1.00 90.58  ?  1007 MET   A HB3  1 
ATOM   4885 H  HG2  . MET   A 1 315 ? 57.332 17.329  12.930 1.00 96.74  ?  1007 MET   A HG2  1 
ATOM   4886 H  HG3  . MET   A 1 315 ? 57.979 15.783  12.540 1.00 96.74  ?  1007 MET   A HG3  1 
ATOM   4887 H  HE1  . MET   A 1 315 ? 55.800 16.849  16.389 1.00 99.51  ?  1007 MET   A HE1  1 
ATOM   4888 H  HE2  . MET   A 1 315 ? 57.241 17.794  16.019 1.00 99.51  ?  1007 MET   A HE2  1 
ATOM   4889 H  HE3  . MET   A 1 315 ? 55.864 17.798  14.901 1.00 99.51  ?  1007 MET   A HE3  1 
ATOM   4890 N  N    . ASP   A 1 316 ? 61.502 19.941  14.420 1.00 80.14  ?  1008 ASP   A N    1 
ATOM   4891 C  CA   . ASP   A 1 316 ? 62.906 20.292  14.684 1.00 76.97  ?  1008 ASP   A CA   1 
ATOM   4892 C  C    . ASP   A 1 316 ? 63.468 19.903  16.045 1.00 75.00  ?  1008 ASP   A C    1 
ATOM   4893 O  O    . ASP   A 1 316 ? 64.631 19.517  16.144 1.00 83.03  ?  1008 ASP   A O    1 
ATOM   4894 C  CB   . ASP   A 1 316 ? 63.164 21.789  14.463 1.00 76.46  ?  1008 ASP   A CB   1 
ATOM   4895 C  CG   . ASP   A 1 316 ? 63.531 22.161  13.044 1.00 79.55  ?  1008 ASP   A CG   1 
ATOM   4896 O  OD1  . ASP   A 1 316 ? 63.333 21.338  12.125 1.00 66.33  ?  1008 ASP   A OD1  1 
ATOM   4897 O  OD2  . ASP   A 1 316 ? 64.038 23.282  12.832 1.00 84.74  -1 1008 ASP   A OD2  1 
ATOM   4898 H  H    . ASP   A 1 316 ? 60.894 20.632  14.002 1.00 82.14  ?  1008 ASP   A H    1 
ATOM   4899 H  HA   . ASP   A 1 316 ? 63.512 19.715  13.981 1.00 78.97  ?  1008 ASP   A HA   1 
ATOM   4900 H  HB2  . ASP   A 1 316 ? 62.299 22.377  14.751 1.00 78.46  ?  1008 ASP   A HB2  1 
ATOM   4901 H  HB3  . ASP   A 1 316 ? 63.983 22.148  15.091 1.00 78.46  ?  1008 ASP   A HB3  1 
ATOM   4902 N  N    . ASP   A 1 317 ? 62.643 19.975  17.081 1.00 67.59  ?  1009 ASP   A N    1 
ATOM   4903 C  CA   . ASP   A 1 317 ? 63.127 19.719  18.439 1.00 55.76  ?  1009 ASP   A CA   1 
ATOM   4904 C  C    . ASP   A 1 317 ? 62.711 18.342  18.946 1.00 46.76  ?  1009 ASP   A C    1 
ATOM   4905 O  O    . ASP   A 1 317 ? 62.681 18.087  20.150 1.00 39.86  ?  1009 ASP   A O    1 
ATOM   4906 C  CB   . ASP   A 1 317 ? 62.664 20.818  19.405 1.00 64.41  ?  1009 ASP   A CB   1 
ATOM   4907 C  CG   . ASP   A 1 317 ? 63.359 22.146  19.168 1.00 69.05  ?  1009 ASP   A CG   1 
ATOM   4908 O  OD1  . ASP   A 1 317 ? 64.607 22.181  19.144 1.00 74.40  ?  1009 ASP   A OD1  1 
ATOM   4909 O  OD2  . ASP   A 1 317 ? 62.665 23.172  19.018 1.00 74.71  -1 1009 ASP   A OD2  1 
ATOM   4910 H  H    . ASP   A 1 317 ? 61.700 20.296  16.939 1.00 69.59  ?  1009 ASP   A H    1 
ATOM   4911 H  HA   . ASP   A 1 317 ? 64.217 19.700  18.478 1.00 57.76  ?  1009 ASP   A HA   1 
ATOM   4912 H  HB2  . ASP   A 1 317 ? 61.583 20.948  19.359 1.00 66.41  ?  1009 ASP   A HB2  1 
ATOM   4913 H  HB3  . ASP   A 1 317 ? 62.889 20.551  20.438 1.00 66.41  ?  1009 ASP   A HB3  1 
ATOM   4914 N  N    . VAL   A 1 318 ? 62.375 17.439  18.034 1.00 41.29  ?  1010 VAL   A N    1 
ATOM   4915 C  CA   . VAL   A 1 318 ? 62.046 16.079  18.421 1.00 35.54  ?  1010 VAL   A CA   1 
ATOM   4916 C  C    . VAL   A 1 318 ? 63.273 15.315  18.918 1.00 44.94  ?  1010 VAL   A C    1 
ATOM   4917 O  O    . VAL   A 1 318 ? 64.346 15.339  18.311 1.00 59.58  ?  1010 VAL   A O    1 
ATOM   4918 C  CB   . VAL   A 1 318 ? 61.307 15.374  17.282 1.00 40.92  ?  1010 VAL   A CB   1 
ATOM   4919 C  CG1  . VAL   A 1 318 ? 61.065 13.885  17.493 1.00 26.26  ?  1010 VAL   A CG1  1 
ATOM   4920 C  CG2  . VAL   A 1 318 ? 59.960 16.049  17.055 1.00 37.79  ?  1010 VAL   A CG2  1 
ATOM   4921 H  H    . VAL   A 1 318 ? 62.452 17.665  17.052 1.00 43.29  ?  1010 VAL   A H    1 
ATOM   4922 H  HA   . VAL   A 1 318 ? 61.342 16.160  19.236 1.00 37.54  ?  1010 VAL   A HA   1 
ATOM   4923 H  HB   . VAL   A 1 318 ? 61.899 15.475  16.371 1.00 42.92  ?  1010 VAL   A HB   1 
ATOM   4924 H  HG11 . VAL   A 1 318 ? 60.478 13.458  16.679 1.00 28.26  ?  1010 VAL   A HG11 1 
ATOM   4925 H  HG12 . VAL   A 1 318 ? 61.996 13.318  17.534 1.00 28.26  ?  1010 VAL   A HG12 1 
ATOM   4926 H  HG13 . VAL   A 1 318 ? 60.525 13.705  18.421 1.00 28.26  ?  1010 VAL   A HG13 1 
ATOM   4927 H  HG21 . VAL   A 1 318 ? 59.438 15.571  16.231 1.00 39.79  ?  1010 VAL   A HG21 1 
ATOM   4928 H  HG22 . VAL   A 1 318 ? 59.318 15.962  17.932 1.00 39.79  ?  1010 VAL   A HG22 1 
ATOM   4929 H  HG23 . VAL   A 1 318 ? 60.054 17.107  16.820 1.00 39.79  ?  1010 VAL   A HG23 1 
ATOM   4930 N  N    . VAL   A 1 319 ? 63.086 14.654  20.048 1.00 48.41  ?  1011 VAL   A N    1 
ATOM   4931 C  CA   . VAL   A 1 319 ? 64.103 13.848  20.706 1.00 43.82  ?  1011 VAL   A CA   1 
ATOM   4932 C  C    . VAL   A 1 319 ? 63.405 12.543  21.033 1.00 35.16  ?  1011 VAL   A C    1 
ATOM   4933 O  O    . VAL   A 1 319 ? 62.284 12.548  21.542 1.00 38.71  ?  1011 VAL   A O    1 
ATOM   4934 C  CB   . VAL   A 1 319 ? 64.648 14.553  21.963 1.00 46.63  ?  1011 VAL   A CB   1 
ATOM   4935 C  CG1  . VAL   A 1 319 ? 65.760 13.798  22.675 1.00 50.13  ?  1011 VAL   A CG1  1 
ATOM   4936 C  CG2  . VAL   A 1 319 ? 65.110 15.976  21.710 1.00 50.48  ?  1011 VAL   A CG2  1 
ATOM   4937 H  H    . VAL   A 1 319 ? 62.164 14.656  20.483 1.00 50.41  ?  1011 VAL   A H    1 
ATOM   4938 H  HA   . VAL   A 1 319 ? 64.932 13.641  20.025 1.00 45.82  ?  1011 VAL   A HA   1 
ATOM   4939 H  HB   . VAL   A 1 319 ? 63.818 14.614  22.669 1.00 48.63  ?  1011 VAL   A HB   1 
ATOM   4940 H  HG11 . VAL   A 1 319 ? 66.078 14.328  23.572 1.00 52.13  ?  1011 VAL   A HG11 1 
ATOM   4941 H  HG12 . VAL   A 1 319 ? 65.437 12.816  23.006 1.00 52.13  ?  1011 VAL   A HG12 1 
ATOM   4942 H  HG13 . VAL   A 1 319 ? 66.635 13.667  22.038 1.00 52.13  ?  1011 VAL   A HG13 1 
ATOM   4943 H  HG21 . VAL   A 1 319 ? 65.319 16.469  22.656 1.00 52.48  ?  1011 VAL   A HG21 1 
ATOM   4944 H  HG22 . VAL   A 1 319 ? 66.009 16.002  21.095 1.00 52.48  ?  1011 VAL   A HG22 1 
ATOM   4945 H  HG23 . VAL   A 1 319 ? 64.354 16.586  21.225 1.00 52.48  ?  1011 VAL   A HG23 1 
ATOM   4946 N  N    . ASP   A 1 320 ? 64.052 11.419  20.772 1.00 30.62  ?  1012 ASP   A N    1 
ATOM   4947 C  CA   . ASP   A 1 320 ? 63.482 10.160  21.243 1.00 29.50  ?  1012 ASP   A CA   1 
ATOM   4948 C  C    . ASP   A 1 320 ? 63.721 10.024  22.745 1.00 31.74  ?  1012 ASP   A C    1 
ATOM   4949 O  O    . ASP   A 1 320 ? 64.736 10.490  23.271 1.00 27.10  ?  1012 ASP   A O    1 
ATOM   4950 C  CB   . ASP   A 1 320 ? 64.124 9.010   20.470 1.00 32.82  ?  1012 ASP   A CB   1 
ATOM   4951 C  CG   . ASP   A 1 320 ? 63.540 7.661   20.813 1.00 41.89  ?  1012 ASP   A CG   1 
ATOM   4952 O  OD1  . ASP   A 1 320 ? 64.101 6.966   21.685 1.00 52.29  ?  1012 ASP   A OD1  1 
ATOM   4953 O  OD2  . ASP   A 1 320 ? 62.510 7.282   20.219 1.00 71.78  -1 1012 ASP   A OD2  1 
ATOM   4954 H  H    . ASP   A 1 320 ? 65.005 11.437  20.449 1.00 32.62  ?  1012 ASP   A H    1 
ATOM   4955 H  HA   . ASP   A 1 320 ? 62.408 10.140  21.041 1.00 31.50  ?  1012 ASP   A HA   1 
ATOM   4956 H  HB2  . ASP   A 1 320 ? 63.992 9.167   19.399 1.00 34.82  ?  1012 ASP   A HB2  1 
ATOM   4957 H  HB3  . ASP   A 1 320 ? 65.195 8.988   20.645 1.00 34.82  ?  1012 ASP   A HB3  1 
ATOM   4958 N  N    . ALA   A 1 321 ? 62.798 9.367   23.434 1.00 29.02  ?  1013 ALA   A N    1 
ATOM   4959 C  CA   . ALA   A 1 321 ? 62.909 9.171   24.879 1.00 37.25  ?  1013 ALA   A CA   1 
ATOM   4960 C  C    . ALA   A 1 321 ? 64.213 8.548   25.372 1.00 26.79  ?  1013 ALA   A C    1 
ATOM   4961 O  O    . ALA   A 1 321 ? 64.699 8.897   26.443 1.00 46.02  ?  1013 ALA   A O    1 
ATOM   4962 C  CB   . ALA   A 1 321 ? 61.724 8.384   25.406 1.00 25.97  ?  1013 ALA   A CB   1 
ATOM   4963 H  H    . ALA   A 1 321 ? 61.958 9.041   22.949 1.00 31.02  ?  1013 ALA   A H    1 
ATOM   4964 H  HA   . ALA   A 1 321 ? 62.856 10.165  25.326 1.00 39.25  ?  1013 ALA   A HA   1 
ATOM   4965 H  HB1  . ALA   A 1 321 ? 61.777 8.288   26.490 1.00 27.97  ?  1013 ALA   A HB1  1 
ATOM   4966 H  HB2  . ALA   A 1 321 ? 60.780 8.871   25.164 1.00 27.97  ?  1013 ALA   A HB2  1 
ATOM   4967 H  HB3  . ALA   A 1 321 ? 61.698 7.378   24.985 1.00 27.97  ?  1013 ALA   A HB3  1 
ATOM   4968 N  N    . ASP   A 1 322 ? 64.827 7.703   24.551 1.00 30.94  ?  1014 ASP   A N    1 
ATOM   4969 C  CA   . ASP   A 1 322 ? 66.114 7.089   24.902 1.00 37.65  ?  1014 ASP   A CA   1 
ATOM   4970 C  C    . ASP   A 1 322 ? 67.288 8.054   24.948 1.00 46.60  ?  1014 ASP   A C    1 
ATOM   4971 O  O    . ASP   A 1 322 ? 68.319 7.757   25.559 1.00 47.75  ?  1014 ASP   A O    1 
ATOM   4972 C  CB   . ASP   A 1 322 ? 66.471 5.967   23.918 1.00 22.63  ?  1014 ASP   A CB   1 
ATOM   4973 C  CG   . ASP   A 1 322 ? 65.531 4.785   24.010 1.00 37.18  ?  1014 ASP   A CG   1 
ATOM   4974 O  OD1  . ASP   A 1 322 ? 64.865 4.618   25.053 1.00 40.70  ?  1014 ASP   A OD1  1 
ATOM   4975 O  OD2  . ASP   A 1 322 ? 65.445 4.002   23.042 1.00 30.14  -1 1014 ASP   A OD2  1 
ATOM   4976 H  H    . ASP   A 1 322 ? 64.417 7.498   23.649 1.00 32.94  ?  1014 ASP   A H    1 
ATOM   4977 H  HA   . ASP   A 1 322 ? 66.039 6.676   25.911 1.00 39.65  ?  1014 ASP   A HA   1 
ATOM   4978 H  HB2  . ASP   A 1 322 ? 66.490 6.347   22.895 1.00 24.63  ?  1014 ASP   A HB2  1 
ATOM   4979 H  HB3  . ASP   A 1 322 ? 67.474 5.588   24.121 1.00 24.63  ?  1014 ASP   A HB3  1 
ATOM   4980 N  N    . GLU   A 1 323 ? 67.123 9.203   24.303 1.00 40.53  ?  1015 GLU   A N    1 
ATOM   4981 C  CA   . GLU   A 1 323 ? 68.140 10.243  24.316 1.00 37.94  ?  1015 GLU   A CA   1 
ATOM   4982 C  C    . GLU   A 1 323 ? 67.776 11.331  25.321 1.00 34.09  ?  1015 GLU   A C    1 
ATOM   4983 O  O    . GLU   A 1 323 ? 68.600 12.199  25.616 1.00 40.68  ?  1015 GLU   A O    1 
ATOM   4984 C  CB   . GLU   A 1 323 ? 68.247 10.867  22.922 1.00 34.07  ?  1015 GLU   A CB   1 
ATOM   4985 C  CG   . GLU   A 1 323 ? 69.158 10.132  21.926 1.00 37.10  ?  1015 GLU   A CG   1 
ATOM   4986 C  CD   . GLU   A 1 323 ? 68.628 8.752   21.628 1.00 47.32  ?  1015 GLU   A CD   1 
ATOM   4987 O  OE1  . GLU   A 1 323 ? 67.562 8.642   20.990 1.00 57.46  ?  1015 GLU   A OE1  1 
ATOM   4988 O  OE2  . GLU   A 1 323 ? 69.278 7.758   22.021 1.00 46.32  -1 1015 GLU   A OE2  1 
ATOM   4989 H  H    . GLU   A 1 323 ? 66.245 9.393   23.830 1.00 42.53  ?  1015 GLU   A H    1 
ATOM   4990 H  HA   . GLU   A 1 323 ? 69.123 9.864   24.602 1.00 39.94  ?  1015 GLU   A HA   1 
ATOM   4991 H  HB2  . GLU   A 1 323 ? 67.254 11.003  22.490 1.00 36.07  ?  1015 GLU   A HB2  1 
ATOM   4992 H  HB3  . GLU   A 1 323 ? 68.652 11.879  22.998 1.00 36.07  ?  1015 GLU   A HB3  1 
ATOM   4993 H  HG2  . GLU   A 1 323 ? 69.167 10.656  20.975 1.00 39.10  ?  1015 GLU   A HG2  1 
ATOM   4994 H  HG3  . GLU   A 1 323 ? 70.179 10.069  22.301 1.00 39.10  ?  1015 GLU   A HG3  1 
ATOM   4995 N  N    . TYR   A 1 324 ? 66.567 11.290  25.868 1.00 35.26  ?  1016 TYR   A N    1 
ATOM   4996 C  CA   . TYR   A 1 324 ? 66.164 12.258  26.871 1.00 44.06  ?  1016 TYR   A CA   1 
ATOM   4997 C  C    . TYR   A 1 324 ? 66.355 11.615  28.240 1.00 48.24  ?  1016 TYR   A C    1 
ATOM   4998 O  O    . TYR   A 1 324 ? 65.462 10.967  28.792 1.00 49.78  ?  1016 TYR   A O    1 
ATOM   4999 C  CB   . TYR   A 1 324 ? 64.718 12.673  26.630 1.00 33.34  ?  1016 TYR   A CB   1 
ATOM   5000 C  CG   . TYR   A 1 324 ? 64.247 13.746  27.595 1.00 56.53  ?  1016 TYR   A CG   1 
ATOM   5001 C  CD1  . TYR   A 1 324 ? 64.661 15.081  27.426 1.00 59.32  ?  1016 TYR   A CD1  1 
ATOM   5002 C  CD2  . TYR   A 1 324 ? 63.403 13.404  28.672 1.00 60.25  ?  1016 TYR   A CD2  1 
ATOM   5003 C  CE1  . TYR   A 1 324 ? 64.245 16.067  28.338 1.00 66.34  ?  1016 TYR   A CE1  1 
ATOM   5004 C  CE2  . TYR   A 1 324 ? 62.991 14.389  29.583 1.00 64.93  ?  1016 TYR   A CE2  1 
ATOM   5005 C  CZ   . TYR   A 1 324 ? 63.415 15.718  29.423 1.00 60.60  ?  1016 TYR   A CZ   1 
ATOM   5006 O  OH   . TYR   A 1 324 ? 63.024 16.667  30.322 1.00 74.82  ?  1016 TYR   A OH   1 
ATOM   5007 H  H    . TYR   A 1 324 ? 65.977 10.482  25.711 1.00 37.26  ?  1016 TYR   A H    1 
ATOM   5008 H  HA   . TYR   A 1 324 ? 66.763 13.169  26.828 1.00 46.06  ?  1016 TYR   A HA   1 
ATOM   5009 H  HB2  . TYR   A 1 324 ? 64.605 13.054  25.614 1.00 35.34  ?  1016 TYR   A HB2  1 
ATOM   5010 H  HB3  . TYR   A 1 324 ? 64.055 11.808  26.694 1.00 35.34  ?  1016 TYR   A HB3  1 
ATOM   5011 H  HD1  . TYR   A 1 324 ? 65.301 15.348  26.597 1.00 61.32  ?  1016 TYR   A HD1  1 
ATOM   5012 H  HD2  . TYR   A 1 324 ? 63.078 12.381  28.801 1.00 62.25  ?  1016 TYR   A HD2  1 
ATOM   5013 H  HE1  . TYR   A 1 324 ? 64.566 17.088  28.206 1.00 68.34  ?  1016 TYR   A HE1  1 
ATOM   5014 H  HE2  . TYR   A 1 324 ? 62.350 14.124  30.407 1.00 66.93  ?  1016 TYR   A HE2  1 
ATOM   5015 H  HH   . TYR   A 1 324 ? 63.431 17.512  30.165 1.00 76.82  ?  1016 TYR   A HH   1 
ATOM   5016 N  N    . LEU   A 1 325 ? 67.566 11.756  28.767 1.00 63.85  ?  1017 LEU   A N    1 
ATOM   5017 C  CA   . LEU   A 1 325 ? 67.908 11.128  30.032 1.00 71.70  ?  1017 LEU   A CA   1 
ATOM   5018 C  C    . LEU   A 1 325 ? 67.582 12.099  31.153 1.00 77.76  ?  1017 LEU   A C    1 
ATOM   5019 O  O    . LEU   A 1 325 ? 67.997 13.261  31.139 1.00 64.96  ?  1017 LEU   A O    1 
ATOM   5020 C  CB   . LEU   A 1 325 ? 69.406 10.799  30.100 1.00 64.58  ?  1017 LEU   A CB   1 
ATOM   5021 C  CG   . LEU   A 1 325 ? 69.844 9.572   29.292 1.00 53.34  ?  1017 LEU   A CG   1 
ATOM   5022 C  CD1  . LEU   A 1 325 ? 70.018 9.850   27.811 1.00 63.97  ?  1017 LEU   A CD1  1 
ATOM   5023 C  CD2  . LEU   A 1 325 ? 71.134 8.984   29.830 1.00 70.12  ?  1017 LEU   A CD2  1 
ATOM   5024 H  H    . LEU   A 1 325 ? 68.275 12.336  28.321 1.00 65.85  ?  1017 LEU   A H    1 
ATOM   5025 H  HA   . LEU   A 1 325 ? 67.351 10.199  30.178 1.00 73.70  ?  1017 LEU   A HA   1 
ATOM   5026 H  HB2  . LEU   A 1 325 ? 70.008 11.669  29.831 1.00 66.58  ?  1017 LEU   A HB2  1 
ATOM   5027 H  HB3  . LEU   A 1 325 ? 69.650 10.603  31.146 1.00 66.58  ?  1017 LEU   A HB3  1 
ATOM   5028 H  HG   . LEU   A 1 325 ? 69.081 8.800   29.401 1.00 55.34  ?  1017 LEU   A HG   1 
ATOM   5029 H  HD11 . LEU   A 1 325 ? 70.439 8.991   27.286 1.00 65.97  ?  1017 LEU   A HD11 1 
ATOM   5030 H  HD12 . LEU   A 1 325 ? 69.058 10.052  27.348 1.00 65.97  ?  1017 LEU   A HD12 1 
ATOM   5031 H  HD13 . LEU   A 1 325 ? 70.671 10.704  27.632 1.00 65.97  ?  1017 LEU   A HD13 1 
ATOM   5032 H  HD21 . LEU   A 1 325 ? 71.365 8.035   29.342 1.00 72.12  ?  1017 LEU   A HD21 1 
ATOM   5033 H  HD22 . LEU   A 1 325 ? 71.973 9.653   29.649 1.00 72.12  ?  1017 LEU   A HD22 1 
ATOM   5034 H  HD23 . LEU   A 1 325 ? 71.075 8.784   30.901 1.00 72.12  ?  1017 LEU   A HD23 1 
ATOM   5035 N  N    . ILE   A 1 326 ? 66.841 11.609  32.140 1.00 95.12  ?  1018 ILE   A N    1 
ATOM   5036 C  CA   . ILE   A 1 326 ? 66.497 12.402  33.319 1.00 101.55 ?  1018 ILE   A CA   1 
ATOM   5037 C  C    . ILE   A 1 326 ? 67.758 12.539  34.191 1.00 105.38 ?  1018 ILE   A C    1 
ATOM   5038 O  O    . ILE   A 1 326 ? 68.434 11.530  34.423 1.00 103.41 ?  1018 ILE   A O    1 
ATOM   5039 C  CB   . ILE   A 1 326 ? 65.343 11.724  34.105 1.00 103.18 ?  1018 ILE   A CB   1 
ATOM   5040 C  CG1  . ILE   A 1 326 ? 64.150 11.364  33.201 1.00 109.97 ?  1018 ILE   A CG1  1 
ATOM   5041 C  CG2  . ILE   A 1 326 ? 64.870 12.559  35.298 1.00 100.06 ?  1018 ILE   A CG2  1 
ATOM   5042 C  CD1  . ILE   A 1 326 ? 63.014 10.603  33.880 1.00 111.46 ?  1018 ILE   A CD1  1 
ATOM   5043 H  H    . ILE   A 1 326 ? 66.554 10.643  32.109 1.00 97.12  ?  1018 ILE   A H    1 
ATOM   5044 H  HA   . ILE   A 1 326 ? 66.139 13.370  32.967 1.00 103.55 ?  1018 ILE   A HA   1 
ATOM   5045 H  HB   . ILE   A 1 326 ? 65.731 10.787  34.511 1.00 105.18 ?  1018 ILE   A HB   1 
ATOM   5046 H  HG12 . ILE   A 1 326 ? 63.759 12.263  32.726 1.00 111.97 ?  1018 ILE   A HG12 1 
ATOM   5047 H  HG13 . ILE   A 1 326 ? 64.486 10.731  32.379 1.00 111.97 ?  1018 ILE   A HG13 1 
ATOM   5048 H  HG21 . ILE   A 1 326 ? 64.153 12.016  35.911 1.00 102.06 ?  1018 ILE   A HG21 1 
ATOM   5049 H  HG22 . ILE   A 1 326 ? 65.685 12.827  35.971 1.00 102.06 ?  1018 ILE   A HG22 1 
ATOM   5050 H  HG23 . ILE   A 1 326 ? 64.391 13.483  34.970 1.00 102.06 ?  1018 ILE   A HG23 1 
ATOM   5051 H  HD11 . ILE   A 1 326 ? 62.279 10.271  33.146 1.00 113.46 ?  1018 ILE   A HD11 1 
ATOM   5052 H  HD12 . ILE   A 1 326 ? 63.389 9.714   34.389 1.00 113.46 ?  1018 ILE   A HD12 1 
ATOM   5053 H  HD13 . ILE   A 1 326 ? 62.487 11.210  34.614 1.00 113.46 ?  1018 ILE   A HD13 1 
ATOM   5054 N  N    . PRO   A 1 327 ? 68.101 13.752  34.659 1.00 108.37 ?  1019 PRO   A N    1 
ATOM   5055 C  CA   . PRO   A 1 327 ? 69.375 13.929  35.381 1.00 107.50 ?  1019 PRO   A CA   1 
ATOM   5056 C  C    . PRO   A 1 327 ? 69.384 13.253  36.765 1.00 104.32 ?  1019 PRO   A C    1 
ATOM   5057 O  O    . PRO   A 1 327 ? 68.552 13.467  37.645 1.00 110.99 ?  1019 PRO   A O    1 
ATOM   5058 C  CB   . PRO   A 1 327 ? 69.553 15.454  35.524 1.00 106.16 ?  1019 PRO   A CB   1 
ATOM   5059 C  CG   . PRO   A 1 327 ? 68.204 16.088  35.188 1.00 106.15 ?  1019 PRO   A CG   1 
ATOM   5060 C  CD   . PRO   A 1 327 ? 67.390 15.017  34.461 1.00 106.34 ?  1019 PRO   A CD   1 
ATOM   5061 H  HA   . PRO   A 1 327 ? 70.196 13.523  34.786 1.00 109.50 ?  1019 PRO   A HA   1 
ATOM   5062 H  HB2  . PRO   A 1 327 ? 69.890 15.758  36.517 1.00 108.16 ?  1019 PRO   A HB2  1 
ATOM   5063 H  HB3  . PRO   A 1 327 ? 70.320 15.805  34.837 1.00 108.16 ?  1019 PRO   A HB3  1 
ATOM   5064 H  HG2  . PRO   A 1 327 ? 67.694 16.372  36.110 1.00 108.15 ?  1019 PRO   A HG2  1 
ATOM   5065 H  HG3  . PRO   A 1 327 ? 68.313 16.993  34.588 1.00 108.15 ?  1019 PRO   A HG3  1 
ATOM   5066 H  HD2  . PRO   A 1 327 ? 66.374 14.971  34.853 1.00 108.34 ?  1019 PRO   A HD2  1 
ATOM   5067 H  HD3  . PRO   A 1 327 ? 67.329 15.246  33.397 1.00 108.34 ?  1019 PRO   A HD3  1 
HETATM 5068 C  C1   . A1A5V B 2 .   ? 48.122 -3.447  27.071 1.00 89.96  ?  1101 A1A5V A C1   1 
HETATM 5069 C  C3   . A1A5V B 2 .   ? 49.618 -1.538  26.977 1.00 84.02  ?  1101 A1A5V A C3   1 
HETATM 5070 C  C4   . A1A5V B 2 .   ? 49.917 -1.572  25.482 1.00 83.09  ?  1101 A1A5V A C4   1 
HETATM 5071 C  C5   . A1A5V B 2 .   ? 51.113 -0.657  25.198 1.00 67.75  ?  1101 A1A5V A C5   1 
HETATM 5072 C  C7   . A1A5V B 2 .   ? 52.088 -1.324  27.454 1.00 74.48  ?  1101 A1A5V A C7   1 
HETATM 5073 C  C8   . A1A5V B 2 .   ? 50.819 -2.160  27.702 1.00 79.05  ?  1101 A1A5V A C8   1 
HETATM 5074 N  N10  . A1A5V B 2 .   ? 54.457 -0.267  26.652 1.00 60.57  ?  1101 A1A5V A N10  1 
HETATM 5075 C  C11  . A1A5V B 2 .   ? 55.496 0.553   26.428 1.00 46.48  ?  1101 A1A5V A C11  1 
HETATM 5076 C  C12  . A1A5V B 2 .   ? 55.571 1.368   25.306 1.00 55.34  ?  1101 A1A5V A C12  1 
HETATM 5077 C  C15  . A1A5V B 2 .   ? 53.748 1.903   22.078 1.00 54.87  ?  1101 A1A5V A C15  1 
HETATM 5078 C  C18  . A1A5V B 2 .   ? 52.699 2.174   18.832 1.00 61.66  ?  1101 A1A5V A C18  1 
HETATM 5079 C  C19  . A1A5V B 2 .   ? 51.640 1.178   18.625 1.00 61.70  ?  1101 A1A5V A C19  1 
HETATM 5080 C  C23  . A1A5V B 2 .   ? 51.271 -1.814  20.521 1.00 69.18  ?  1101 A1A5V A C23  1 
HETATM 5081 C  C24  . A1A5V B 2 .   ? 49.501 -0.081  21.196 1.00 58.28  ?  1101 A1A5V A C24  1 
HETATM 5082 O  O2   . A1A5V B 2 .   ? 48.348 -2.072  27.346 1.00 89.24  ?  1101 A1A5V A O2   1 
HETATM 5083 N  N6   . A1A5V B 2 .   ? 52.295 -0.890  26.055 1.00 75.14  ?  1101 A1A5V A N6   1 
HETATM 5084 C  C9   . A1A5V B 2 .   ? 53.471 -0.183  25.755 1.00 59.62  ?  1101 A1A5V A C9   1 
HETATM 5085 C  C13  . A1A5V B 2 .   ? 54.517 1.306   24.406 1.00 50.80  ?  1101 A1A5V A C13  1 
HETATM 5086 N  N14  . A1A5V B 2 .   ? 54.554 2.079   23.227 1.00 54.90  ?  1101 A1A5V A N14  1 
HETATM 5087 N  N16  . A1A5V B 2 .   ? 53.973 2.665   20.879 1.00 54.32  ?  1101 A1A5V A N16  1 
HETATM 5088 N  N17  . A1A5V B 2 .   ? 53.044 2.027   20.139 1.00 65.82  ?  1101 A1A5V A N17  1 
HETATM 5089 C  C20  . A1A5V B 2 .   ? 50.991 1.009   17.266 1.00 48.17  ?  1101 A1A5V A C20  1 
HETATM 5090 N  N21  . A1A5V B 2 .   ? 51.481 0.565   19.841 1.00 62.89  ?  1101 A1A5V A N21  1 
HETATM 5091 C  C22  . A1A5V B 2 .   ? 50.542 -0.510  20.148 1.00 66.14  ?  1101 A1A5V A C22  1 
HETATM 5092 C  C25  . A1A5V B 2 .   ? 52.361 1.129   20.680 1.00 63.77  ?  1101 A1A5V A C25  1 
HETATM 5093 C  C26  . A1A5V B 2 .   ? 52.657 0.904   21.952 1.00 56.82  ?  1101 A1A5V A C26  1 
HETATM 5094 N  N27  . A1A5V B 2 .   ? 53.459 0.517   24.620 1.00 57.60  ?  1101 A1A5V A N27  1 
HETATM 5095 H  H1_1 . A1A5V B 2 .   ? 47.105 -3.703  27.370 1.00 91.96  ?  1101 A1A5V A H1_1 1 
HETATM 5096 H  H1_3 . A1A5V B 2 .   ? 48.801 -4.088  27.634 1.00 91.96  ?  1101 A1A5V A H1_3 1 
HETATM 5097 H  H1_2 . A1A5V B 2 .   ? 48.216 -3.673  26.009 1.00 91.96  ?  1101 A1A5V A H1_2 1 
HETATM 5098 H  HC3  . A1A5V B 2 .   ? 49.556 -0.489  27.249 1.00 86.02  ?  1101 A1A5V A HC3  1 
HETATM 5099 H  H4_2 . A1A5V B 2 .   ? 50.138 -2.588  25.155 1.00 85.09  ?  1101 A1A5V A H4_2 1 
HETATM 5100 H  H4_1 . A1A5V B 2 .   ? 49.050 -1.245  24.908 1.00 85.09  ?  1101 A1A5V A H4_1 1 
HETATM 5101 H  H5_1 . A1A5V B 2 .   ? 50.817 0.390   25.275 1.00 69.75  ?  1101 A1A5V A H5_1 1 
HETATM 5102 H  H5_2 . A1A5V B 2 .   ? 51.391 -0.836  24.163 1.00 69.75  ?  1101 A1A5V A H5_2 1 
HETATM 5103 H  H7_1 . A1A5V B 2 .   ? 52.051 -0.429  28.076 1.00 76.48  ?  1101 A1A5V A H7_1 1 
HETATM 5104 H  H7_2 . A1A5V B 2 .   ? 52.947 -1.899  27.801 1.00 76.48  ?  1101 A1A5V A H7_2 1 
HETATM 5105 H  H8_1 . A1A5V B 2 .   ? 50.980 -3.183  27.360 1.00 81.05  ?  1101 A1A5V A H8_1 1 
HETATM 5106 H  H8_2 . A1A5V B 2 .   ? 50.632 -2.222  28.774 1.00 81.05  ?  1101 A1A5V A H8_2 1 
HETATM 5107 H  HC11 . A1A5V B 2 .   ? 56.283 0.550   27.161 1.00 48.48  ?  1101 A1A5V A HC11 1 
HETATM 5108 H  HC12 . A1A5V B 2 .   ? 56.422 2.010   25.137 1.00 57.34  ?  1101 A1A5V A HC12 1 
HETATM 5109 H  HC18 . A1A5V B 2 .   ? 53.185 2.898   18.190 1.00 63.66  ?  1101 A1A5V A HC18 1 
HETATM 5110 H  H232 . A1A5V B 2 .   ? 51.945 -2.125  19.722 1.00 71.18  ?  1101 A1A5V A H232 1 
HETATM 5111 H  H231 . A1A5V B 2 .   ? 50.559 -2.625  20.675 1.00 71.18  ?  1101 A1A5V A H231 1 
HETATM 5112 H  H233 . A1A5V B 2 .   ? 51.859 -1.724  21.432 1.00 71.18  ?  1101 A1A5V A H233 1 
HETATM 5113 H  H243 . A1A5V B 2 .   ? 48.965 0.811   20.873 1.00 60.28  ?  1101 A1A5V A H243 1 
HETATM 5114 H  H242 . A1A5V B 2 .   ? 49.949 0.133   22.165 1.00 60.28  ?  1101 A1A5V A H242 1 
HETATM 5115 H  H241 . A1A5V B 2 .   ? 48.758 -0.865  21.346 1.00 60.28  ?  1101 A1A5V A H241 1 
HETATM 5116 H  HN14 . A1A5V B 2 .   ? 55.321 2.744   23.152 1.00 56.90  ?  1101 A1A5V A HN14 1 
HETATM 5117 H  H203 . A1A5V B 2 .   ? 51.431 1.682   16.530 1.00 50.17  ?  1101 A1A5V A H203 1 
HETATM 5118 H  H202 . A1A5V B 2 .   ? 49.921 1.207   17.328 1.00 50.17  ?  1101 A1A5V A H202 1 
HETATM 5119 H  H201 . A1A5V B 2 .   ? 51.126 -0.014  16.913 1.00 50.17  ?  1101 A1A5V A H201 1 
HETATM 5120 H  HC22 . A1A5V B 2 .   ? 49.988 -0.719  19.231 1.00 68.14  ?  1101 A1A5V A HC22 1 
HETATM 5121 H  HC26 . A1A5V B 2 .   ? 52.210 0.166   22.587 1.00 58.82  ?  1101 A1A5V A HC26 1 
HETATM 5122 CL CL   . CL    C 3 .   ? 73.019 -24.418 24.889 1.00 99.08  -1 1102 CL    A CL   1 
HETATM 5123 CL CL   . CL    D 3 .   ? 70.503 -1.295  19.269 1.00 83.69  -1 1103 CL    A CL   1 
HETATM 5124 CL CL   . CL    E 3 .   ? 65.000 -27.142 7.482  1.00 102.99 -1 1104 CL    A CL   1 
HETATM 5125 CL CL   . CL    F 3 .   ? 54.517 -23.867 11.126 1.00 93.34  -1 1105 CL    A CL   1 
HETATM 5126 O  O    . HOH   G 4 .   ? 52.832 -24.376 27.334 1.00 37.83  ?  1201 HOH   A O    1 
HETATM 5127 H  H1   . HOH   G 4 .   ? 51.986 -23.861 27.524 1.00 39.83  ?  1201 HOH   A H1   1 
HETATM 5128 H  H2   . HOH   G 4 .   ? 53.501 -24.169 28.064 1.00 39.83  ?  1201 HOH   A H2   1 
HETATM 5129 O  O    . HOH   G 4 .   ? 70.929 -15.417 32.392 1.00 33.16  ?  1202 HOH   A O    1 
HETATM 5130 H  H1   . HOH   G 4 .   ? 71.122 -14.437 32.240 1.00 35.16  ?  1202 HOH   A H1   1 
HETATM 5131 H  H2   . HOH   G 4 .   ? 70.090 -15.497 32.940 1.00 35.16  ?  1202 HOH   A H2   1 
HETATM 5132 O  O    . HOH   G 4 .   ? 68.456 -17.687 4.513  1.00 33.58  ?  1203 HOH   A O    1 
HETATM 5133 H  H1   . HOH   G 4 .   ? 68.745 -18.161 5.357  1.00 35.58  ?  1203 HOH   A H1   1 
HETATM 5134 H  H2   . HOH   G 4 .   ? 68.780 -16.736 4.547  1.00 35.58  ?  1203 HOH   A H2   1 
HETATM 5135 O  O    . HOH   G 4 .   ? 53.419 -4.085  14.453 1.00 48.16  ?  1204 HOH   A O    1 
HETATM 5136 H  H1   . HOH   G 4 .   ? 54.034 -3.292  14.346 1.00 50.16  ?  1204 HOH   A H1   1 
HETATM 5137 H  H2   . HOH   G 4 .   ? 53.903 -4.799  14.974 1.00 50.16  ?  1204 HOH   A H2   1 
HETATM 5138 O  O    . HOH   G 4 .   ? 69.741 13.422  27.701 1.00 34.76  ?  1205 HOH   A O    1 
HETATM 5139 H  H1   . HOH   G 4 .   ? 70.230 14.277  27.490 1.00 36.76  ?  1205 HOH   A H1   1 
HETATM 5140 H  H2   . HOH   G 4 .   ? 69.450 12.991  26.836 1.00 36.76  ?  1205 HOH   A H2   1 
HETATM 5141 O  O    . HOH   G 4 .   ? 73.295 -24.903 10.304 1.00 28.88  ?  1206 HOH   A O    1 
HETATM 5142 H  H1   . HOH   G 4 .   ? 73.119 -23.930 10.097 1.00 30.88  ?  1206 HOH   A H1   1 
HETATM 5143 H  H2   . HOH   G 4 .   ? 73.080 -25.077 11.272 1.00 30.88  ?  1206 HOH   A H2   1 
HETATM 5144 O  O    . HOH   G 4 .   ? 54.323 -9.271  32.877 1.00 42.92  ?  1207 HOH   A O    1 
HETATM 5145 H  H1   . HOH   G 4 .   ? 54.932 -10.065 33.001 1.00 44.92  ?  1207 HOH   A H1   1 
HETATM 5146 H  H2   . HOH   G 4 .   ? 54.552 -8.812  32.009 1.00 44.92  ?  1207 HOH   A H2   1 
HETATM 5147 O  O    . HOH   G 4 .   ? 54.479 -23.971 25.278 1.00 52.30  ?  1208 HOH   A O    1 
HETATM 5148 H  H1   . HOH   G 4 .   ? 54.154 -23.095 24.903 1.00 54.30  ?  1208 HOH   A H1   1 
HETATM 5149 H  H2   . HOH   G 4 .   ? 53.851 -24.248 26.026 1.00 54.30  ?  1208 HOH   A H2   1 
HETATM 5150 O  O    . HOH   G 4 .   ? 56.578 -26.916 22.522 1.00 42.34  ?  1209 HOH   A O    1 
HETATM 5151 H  H1   . HOH   G 4 .   ? 55.670 -26.578 22.807 1.00 44.34  ?  1209 HOH   A H1   1 
HETATM 5152 H  H2   . HOH   G 4 .   ? 57.270 -26.532 23.136 1.00 44.34  ?  1209 HOH   A H2   1 
HETATM 5153 O  O    . HOH   G 4 .   ? 68.001 -17.698 32.524 1.00 34.12  ?  1210 HOH   A O    1 
HETATM 5154 H  H1   . HOH   G 4 .   ? 67.628 -18.549 32.916 1.00 36.12  ?  1210 HOH   A H1   1 
HETATM 5155 H  H2   . HOH   G 4 .   ? 68.049 -17.000 33.244 1.00 36.12  ?  1210 HOH   A H2   1 
HETATM 5156 O  O    . HOH   G 4 .   ? 50.612 -24.284 15.808 1.00 57.79  ?  1211 HOH   A O    1 
HETATM 5157 H  H1   . HOH   G 4 .   ? 50.503 -23.282 15.839 1.00 59.79  ?  1211 HOH   A H1   1 
HETATM 5158 H  H2   . HOH   G 4 .   ? 51.584 -24.504 15.710 1.00 59.79  ?  1211 HOH   A H2   1 
HETATM 5159 O  O    . HOH   G 4 .   ? 63.365 -3.007  47.562 1.00 42.60  ?  1212 HOH   A O    1 
HETATM 5160 H  H1   . HOH   G 4 .   ? 64.336 -3.006  47.292 1.00 44.60  ?  1212 HOH   A H1   1 
HETATM 5161 H  H2   . HOH   G 4 .   ? 63.040 -2.054  47.627 1.00 44.60  ?  1212 HOH   A H2   1 
HETATM 5162 O  O    . HOH   G 4 .   ? 43.853 10.301  40.008 1.00 37.84  ?  1213 HOH   A O    1 
HETATM 5163 H  H1   . HOH   G 4 .   ? 43.759 10.667  39.071 1.00 39.84  ?  1213 HOH   A H1   1 
HETATM 5164 H  H2   . HOH   G 4 .   ? 44.687 9.744   40.056 1.00 39.84  ?  1213 HOH   A H2   1 
HETATM 5165 O  O    . HOH   G 4 .   ? 64.381 0.505   30.156 1.00 29.17  ?  1214 HOH   A O    1 
HETATM 5166 H  H1   . HOH   G 4 .   ? 64.053 0.134   29.277 1.00 31.17  ?  1214 HOH   A H1   1 
HETATM 5167 H  H2   . HOH   G 4 .   ? 63.629 0.493   30.817 1.00 31.17  ?  1214 HOH   A H2   1 
HETATM 5168 O  O    . HOH   G 4 .   ? 59.596 -21.150 9.193  1.00 46.47  ?  1215 HOH   A O    1 
HETATM 5169 H  H1   . HOH   G 4 .   ? 59.680 -20.282 9.701  1.00 48.47  ?  1215 HOH   A H1   1 
HETATM 5170 H  H2   . HOH   G 4 .   ? 59.266 -21.858 9.816  1.00 48.47  ?  1215 HOH   A H2   1 
HETATM 5171 O  O    . HOH   G 4 .   ? 63.091 -13.435 34.233 1.00 30.16  ?  1216 HOH   A O    1 
HETATM 5172 H  H1   . HOH   G 4 .   ? 62.249 -13.757 33.788 1.00 32.16  ?  1216 HOH   A H1   1 
HETATM 5173 H  H2   . HOH   G 4 .   ? 62.927 -12.528 34.639 1.00 32.16  ?  1216 HOH   A H2   1 
HETATM 5174 O  O    . HOH   G 4 .   ? 66.679 -2.397  57.414 1.00 36.53  ?  1217 HOH   A O    1 
HETATM 5175 H  H1   . HOH   G 4 .   ? 67.416 -3.076  57.312 1.00 38.53  ?  1217 HOH   A H1   1 
HETATM 5176 H  H2   . HOH   G 4 .   ? 65.835 -2.801  57.059 1.00 38.53  ?  1217 HOH   A H2   1 
HETATM 5177 O  O    . HOH   G 4 .   ? 48.256 -9.764  13.530 1.00 49.97  ?  1218 HOH   A O    1 
HETATM 5178 H  H1   . HOH   G 4 .   ? 47.378 -9.357  13.268 1.00 51.97  ?  1218 HOH   A H1   1 
HETATM 5179 H  H2   . HOH   G 4 .   ? 48.718 -9.150  14.180 1.00 51.97  ?  1218 HOH   A H2   1 
HETATM 5180 O  O    . HOH   G 4 .   ? 57.420 -17.457 33.338 1.00 47.35  ?  1219 HOH   A O    1 
HETATM 5181 H  H1   . HOH   G 4 .   ? 58.087 -16.747 33.091 1.00 49.35  ?  1219 HOH   A H1   1 
HETATM 5182 H  H2   . HOH   G 4 .   ? 56.779 -17.579 32.577 1.00 49.35  ?  1219 HOH   A H2   1 
HETATM 5183 O  O    . HOH   G 4 .   ? 51.311 -3.772  16.502 1.00 47.91  ?  1220 HOH   A O    1 
HETATM 5184 H  H1   . HOH   G 4 .   ? 50.479 -4.331  16.419 1.00 49.91  ?  1220 HOH   A H1   1 
HETATM 5185 H  H2   . HOH   G 4 .   ? 51.783 -3.762  15.612 1.00 49.91  ?  1220 HOH   A H2   1 
HETATM 5186 O  O    . HOH   G 4 .   ? 57.022 -15.392 30.379 1.00 30.65  ?  1221 HOH   A O    1 
HETATM 5187 H  H1   . HOH   G 4 .   ? 57.800 -15.372 31.012 1.00 32.65  ?  1221 HOH   A H1   1 
HETATM 5188 H  H2   . HOH   G 4 .   ? 56.972 -16.302 29.948 1.00 32.65  ?  1221 HOH   A H2   1 
HETATM 5189 O  O    . HOH   G 4 .   ? 52.382 -13.442 21.118 1.00 49.33  ?  1222 HOH   A O    1 
HETATM 5190 H  H1   . HOH   G 4 .   ? 52.626 -13.921 20.267 1.00 51.33  ?  1222 HOH   A H1   1 
HETATM 5191 H  H2   . HOH   G 4 .   ? 52.313 -14.119 21.854 1.00 51.33  ?  1222 HOH   A H2   1 
HETATM 5192 O  O    . HOH   G 4 .   ? 47.775 19.452  26.863 1.00 59.97  ?  1223 HOH   A O    1 
HETATM 5193 H  H1   . HOH   G 4 .   ? 48.020 18.650  27.420 1.00 61.97  ?  1223 HOH   A H1   1 
HETATM 5194 H  H2   . HOH   G 4 .   ? 48.084 19.290  25.924 1.00 61.97  ?  1223 HOH   A H2   1 
HETATM 5195 O  O    . HOH   G 4 .   ? 72.390 -25.538 18.438 1.00 42.94  ?  1224 HOH   A O    1 
HETATM 5196 H  H1   . HOH   G 4 .   ? 71.537 -25.137 18.089 1.00 44.94  ?  1224 HOH   A H1   1 
HETATM 5197 H  H2   . HOH   G 4 .   ? 73.151 -24.919 18.228 1.00 44.94  ?  1224 HOH   A H2   1 
HETATM 5198 O  O    . HOH   G 4 .   ? 54.452 -2.326  11.070 1.00 74.22  ?  1225 HOH   A O    1 
HETATM 5199 H  H1   . HOH   G 4 .   ? 54.334 -2.396  12.063 1.00 76.22  ?  1225 HOH   A H1   1 
HETATM 5200 H  H2   . HOH   G 4 .   ? 53.702 -2.819  10.617 1.00 76.22  ?  1225 HOH   A H2   1 
HETATM 5201 O  O    . HOH   G 4 .   ? 58.947 8.218   36.036 1.00 50.30  ?  1226 HOH   A O    1 
HETATM 5202 H  H1   . HOH   G 4 .   ? 59.787 7.744   36.310 1.00 52.30  ?  1226 HOH   A H1   1 
HETATM 5203 H  H2   . HOH   G 4 .   ? 59.020 8.497   35.072 1.00 52.30  ?  1226 HOH   A H2   1 
HETATM 5204 O  O    . HOH   G 4 .   ? 60.435 8.603   22.060 1.00 24.41  ?  1227 HOH   A O    1 
HETATM 5205 H  H1   . HOH   G 4 .   ? 59.461 8.844   22.139 1.00 26.41  ?  1227 HOH   A H1   1 
HETATM 5206 H  H2   . HOH   G 4 .   ? 60.585 8.108   21.201 1.00 26.41  ?  1227 HOH   A H2   1 
HETATM 5207 O  O    . HOH   G 4 .   ? 71.218 -6.683  17.837 1.00 47.05  ?  1228 HOH   A O    1 
HETATM 5208 H  H1   . HOH   G 4 .   ? 71.169 -6.790  18.832 1.00 49.05  ?  1228 HOH   A H1   1 
HETATM 5209 H  H2   . HOH   G 4 .   ? 72.111 -6.294  17.599 1.00 49.05  ?  1228 HOH   A H2   1 
HETATM 5210 O  O    . HOH   G 4 .   ? 63.965 -32.633 31.327 1.00 54.61  ?  1229 HOH   A O    1 
HETATM 5211 H  H1   . HOH   G 4 .   ? 64.070 -33.551 31.724 1.00 56.61  ?  1229 HOH   A H1   1 
HETATM 5212 H  H2   . HOH   G 4 .   ? 63.518 -32.718 30.426 1.00 56.61  ?  1229 HOH   A H2   1 
HETATM 5213 O  O    . HOH   G 4 .   ? 47.513 -19.696 25.781 1.00 49.70  ?  1230 HOH   A O    1 
HETATM 5214 H  H1   . HOH   G 4 .   ? 47.485 -19.060 25.010 1.00 51.70  ?  1230 HOH   A H1   1 
HETATM 5215 H  H2   . HOH   G 4 .   ? 46.648 -19.636 26.282 1.00 51.70  ?  1230 HOH   A H2   1 
HETATM 5216 O  O    . HOH   G 4 .   ? 71.161 -4.792  27.102 1.00 34.77  ?  1231 HOH   A O    1 
HETATM 5217 H  H1   . HOH   G 4 .   ? 71.942 -4.388  26.622 1.00 36.77  ?  1231 HOH   A H1   1 
HETATM 5218 H  H2   . HOH   G 4 .   ? 70.313 -4.416  26.723 1.00 36.77  ?  1231 HOH   A H2   1 
HETATM 5219 O  O    . HOH   G 4 .   ? 51.933 20.419  25.537 1.00 73.39  ?  1232 HOH   A O    1 
HETATM 5220 H  H1   . HOH   G 4 .   ? 52.638 19.752  25.784 1.00 75.39  ?  1232 HOH   A H1   1 
HETATM 5221 H  H2   . HOH   G 4 .   ? 51.512 20.774  26.378 1.00 75.39  ?  1232 HOH   A H2   1 
HETATM 5222 O  O    . HOH   G 4 .   ? 54.005 16.562  39.562 1.00 63.83  ?  1233 HOH   A O    1 
HETATM 5223 H  H1   . HOH   G 4 .   ? 54.461 16.227  38.732 1.00 65.83  ?  1233 HOH   A H1   1 
HETATM 5224 H  H2   . HOH   G 4 .   ? 54.589 16.377  40.356 1.00 65.83  ?  1233 HOH   A H2   1 
HETATM 5225 O  O    . HOH   G 4 .   ? 63.439 -4.257  40.884 1.00 58.54  ?  1234 HOH   A O    1 
HETATM 5226 H  H1   . HOH   G 4 .   ? 62.724 -4.355  41.578 1.00 60.54  ?  1234 HOH   A H1   1 
HETATM 5227 H  H2   . HOH   G 4 .   ? 63.795 -5.165  40.653 1.00 60.54  ?  1234 HOH   A H2   1 
HETATM 5228 O  O    . HOH   G 4 .   ? 63.389 6.784   30.075 1.00 44.37  ?  1235 HOH   A O    1 
HETATM 5229 H  H1   . HOH   G 4 .   ? 63.251 6.186   29.285 1.00 46.37  ?  1235 HOH   A H1   1 
HETATM 5230 H  H2   . HOH   G 4 .   ? 63.758 7.660   29.757 1.00 46.37  ?  1235 HOH   A H2   1 
# 
