data_9D2K
# 
_entry.id   9D2K 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9D2K         pdb_00009d2k 10.2210/pdb9d2k/pdb 
WWPDB D_1000287023 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-26 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9D2K 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              arnold@cabm.rutgers.edu 
_pdbx_contact_author.name_first         Eddy 
_pdbx_contact_author.name_last          Arnold 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2612-9622 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ansari, A.' 1 0000-0003-3398-175X 
'Tan, B.'    2 0000-0001-6295-6962 
'Ruiz, F.X.' 3 0000-0002-0457-0030 
'Arnold, E.' 4 0000-0003-2612-9622 
'Wang, J.'   5 0000-0002-4845-4621 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            67 
_citation.language                  ? 
_citation.page_first                20399 
_citation.page_last                 20420 
_citation.title                     'Structure-Based Design of Covalent SARS-CoV-2 Papain-like Protease Inhibitors.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.4c01872 
_citation.pdbx_database_id_PubMed   39499574 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Tan, B.'    1  0000-0001-6295-6962 
primary 'Liang, X.'  2  ?                   
primary 'Ansari, A.' 3  ?                   
primary 'Jadhav, P.' 4  ?                   
primary 'Tan, H.'    5  ?                   
primary 'Li, K.'     6  ?                   
primary 'Ruiz, F.X.' 7  0000-0002-0457-0030 
primary 'Arnold, E.' 8  0000-0003-2612-9622 
primary 'Deng, X.'   9  ?                   
primary 'Wang, J.'   10 0000-0002-4845-4621 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Papain-like protease nsp3' 35943.762 2  3.4.19.12,3.4.22.- ? ? ? 
2 non-polymer syn 
;2-(3-{2-[4-(3,3-dimethylazetidin-1-yl)-4-oxobutanoyl]hydrazin-1-yl}-3-oxopropyl)-N-{(1R)-1-[(3P,5P)-3-(1-ethyl-1H-pyrazol-3-yl)-5-(1-methyl-1H-pyrazol-4-yl)phenyl]ethyl}benzamide
;
652.786   2  ?                  ? ? ? 
3 non-polymer syn 2,3-DIHYDROXY-1,4-DITHIOBUTANE 154.251   1  ?                  ? ? ? 
4 non-polymer syn 'ZINC ION' 65.409    10 ?                  ? ? ? 
5 non-polymer syn 'CHLORIDE ION' 35.453    9  ?                  ? ? ? 
6 water       nat water 18.015    92 ?                  ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SNAEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDP
SFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNK
TVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SNAEVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDP
SFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNK
TVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;2-(3-{2-[4-(3,3-dimethylazetidin-1-yl)-4-oxobutanoyl]hydrazin-1-yl}-3-oxopropyl)-N-{(1R)-1-[(3P,5P)-3-(1-ethyl-1H-pyrazol-3-yl)-5-(1-methyl-1H-pyrazol-4-yl)phenyl]ethyl}benzamide
;
A1A6J 
3 2,3-DIHYDROXY-1,4-DITHIOBUTANE DTT   
4 'ZINC ION' ZN    
5 'CHLORIDE ION' CL    
6 water HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   ASN n 
1 3   ALA n 
1 4   GLU n 
1 5   VAL n 
1 6   ARG n 
1 7   THR n 
1 8   ILE n 
1 9   LYS n 
1 10  VAL n 
1 11  PHE n 
1 12  THR n 
1 13  THR n 
1 14  VAL n 
1 15  ASP n 
1 16  ASN n 
1 17  ILE n 
1 18  ASN n 
1 19  LEU n 
1 20  HIS n 
1 21  THR n 
1 22  GLN n 
1 23  VAL n 
1 24  VAL n 
1 25  ASP n 
1 26  MET n 
1 27  SER n 
1 28  MET n 
1 29  THR n 
1 30  TYR n 
1 31  GLY n 
1 32  GLN n 
1 33  GLN n 
1 34  PHE n 
1 35  GLY n 
1 36  PRO n 
1 37  THR n 
1 38  TYR n 
1 39  LEU n 
1 40  ASP n 
1 41  GLY n 
1 42  ALA n 
1 43  ASP n 
1 44  VAL n 
1 45  THR n 
1 46  LYS n 
1 47  ILE n 
1 48  LYS n 
1 49  PRO n 
1 50  HIS n 
1 51  ASN n 
1 52  SER n 
1 53  HIS n 
1 54  GLU n 
1 55  GLY n 
1 56  LYS n 
1 57  THR n 
1 58  PHE n 
1 59  TYR n 
1 60  VAL n 
1 61  LEU n 
1 62  PRO n 
1 63  ASN n 
1 64  ASP n 
1 65  ASP n 
1 66  THR n 
1 67  LEU n 
1 68  ARG n 
1 69  VAL n 
1 70  GLU n 
1 71  ALA n 
1 72  PHE n 
1 73  GLU n 
1 74  TYR n 
1 75  TYR n 
1 76  HIS n 
1 77  THR n 
1 78  THR n 
1 79  ASP n 
1 80  PRO n 
1 81  SER n 
1 82  PHE n 
1 83  LEU n 
1 84  GLY n 
1 85  ARG n 
1 86  TYR n 
1 87  MET n 
1 88  SER n 
1 89  ALA n 
1 90  LEU n 
1 91  ASN n 
1 92  HIS n 
1 93  THR n 
1 94  LYS n 
1 95  LYS n 
1 96  TRP n 
1 97  LYS n 
1 98  TYR n 
1 99  PRO n 
1 100 GLN n 
1 101 VAL n 
1 102 ASN n 
1 103 GLY n 
1 104 LEU n 
1 105 THR n 
1 106 SER n 
1 107 ILE n 
1 108 LYS n 
1 109 TRP n 
1 110 ALA n 
1 111 ASP n 
1 112 ASN n 
1 113 ASN n 
1 114 CYS n 
1 115 TYR n 
1 116 LEU n 
1 117 ALA n 
1 118 THR n 
1 119 ALA n 
1 120 LEU n 
1 121 LEU n 
1 122 THR n 
1 123 LEU n 
1 124 GLN n 
1 125 GLN n 
1 126 ILE n 
1 127 GLU n 
1 128 LEU n 
1 129 LYS n 
1 130 PHE n 
1 131 ASN n 
1 132 PRO n 
1 133 PRO n 
1 134 ALA n 
1 135 LEU n 
1 136 GLN n 
1 137 ASP n 
1 138 ALA n 
1 139 TYR n 
1 140 TYR n 
1 141 ARG n 
1 142 ALA n 
1 143 ARG n 
1 144 ALA n 
1 145 GLY n 
1 146 GLU n 
1 147 ALA n 
1 148 ALA n 
1 149 ASN n 
1 150 PHE n 
1 151 CYS n 
1 152 ALA n 
1 153 LEU n 
1 154 ILE n 
1 155 LEU n 
1 156 ALA n 
1 157 TYR n 
1 158 CYS n 
1 159 ASN n 
1 160 LYS n 
1 161 THR n 
1 162 VAL n 
1 163 GLY n 
1 164 GLU n 
1 165 LEU n 
1 166 GLY n 
1 167 ASP n 
1 168 VAL n 
1 169 ARG n 
1 170 GLU n 
1 171 THR n 
1 172 MET n 
1 173 SER n 
1 174 TYR n 
1 175 LEU n 
1 176 PHE n 
1 177 GLN n 
1 178 HIS n 
1 179 ALA n 
1 180 ASN n 
1 181 LEU n 
1 182 ASP n 
1 183 SER n 
1 184 CYS n 
1 185 LYS n 
1 186 ARG n 
1 187 VAL n 
1 188 LEU n 
1 189 ASN n 
1 190 VAL n 
1 191 VAL n 
1 192 CYS n 
1 193 LYS n 
1 194 THR n 
1 195 CYS n 
1 196 GLY n 
1 197 GLN n 
1 198 GLN n 
1 199 GLN n 
1 200 THR n 
1 201 THR n 
1 202 LEU n 
1 203 LYS n 
1 204 GLY n 
1 205 VAL n 
1 206 GLU n 
1 207 ALA n 
1 208 VAL n 
1 209 MET n 
1 210 TYR n 
1 211 MET n 
1 212 GLY n 
1 213 THR n 
1 214 LEU n 
1 215 SER n 
1 216 TYR n 
1 217 GLU n 
1 218 GLN n 
1 219 PHE n 
1 220 LYS n 
1 221 LYS n 
1 222 GLY n 
1 223 VAL n 
1 224 GLN n 
1 225 ILE n 
1 226 PRO n 
1 227 CYS n 
1 228 THR n 
1 229 CYS n 
1 230 GLY n 
1 231 LYS n 
1 232 GLN n 
1 233 ALA n 
1 234 THR n 
1 235 LYS n 
1 236 TYR n 
1 237 LEU n 
1 238 VAL n 
1 239 GLN n 
1 240 GLN n 
1 241 GLU n 
1 242 SER n 
1 243 PRO n 
1 244 PHE n 
1 245 VAL n 
1 246 MET n 
1 247 MET n 
1 248 SER n 
1 249 ALA n 
1 250 PRO n 
1 251 PRO n 
1 252 ALA n 
1 253 GLN n 
1 254 TYR n 
1 255 GLU n 
1 256 LEU n 
1 257 LYS n 
1 258 HIS n 
1 259 GLY n 
1 260 THR n 
1 261 PHE n 
1 262 THR n 
1 263 CYS n 
1 264 ALA n 
1 265 SER n 
1 266 GLU n 
1 267 TYR n 
1 268 THR n 
1 269 GLY n 
1 270 ASN n 
1 271 TYR n 
1 272 GLN n 
1 273 CYS n 
1 274 GLY n 
1 275 HIS n 
1 276 TYR n 
1 277 LYS n 
1 278 HIS n 
1 279 ILE n 
1 280 THR n 
1 281 SER n 
1 282 LYS n 
1 283 GLU n 
1 284 THR n 
1 285 LEU n 
1 286 TYR n 
1 287 CYS n 
1 288 ILE n 
1 289 ASP n 
1 290 GLY n 
1 291 ALA n 
1 292 LEU n 
1 293 LEU n 
1 294 THR n 
1 295 LYS n 
1 296 SER n 
1 297 SER n 
1 298 GLU n 
1 299 TYR n 
1 300 LYS n 
1 301 GLY n 
1 302 PRO n 
1 303 ILE n 
1 304 THR n 
1 305 ASP n 
1 306 VAL n 
1 307 PHE n 
1 308 TYR n 
1 309 LYS n 
1 310 GLU n 
1 311 ASN n 
1 312 SER n 
1 313 TYR n 
1 314 THR n 
1 315 THR n 
1 316 THR n 
1 317 ILE n 
1 318 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   318 
_entity_src_gen.gene_src_common_name               'SARS-CoV-2, 2019-nCoV, COVID-19 virus' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rep, 1a-1b' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1A6J non-polymer         . 
;2-(3-{2-[4-(3,3-dimethylazetidin-1-yl)-4-oxobutanoyl]hydrazin-1-yl}-3-oxopropyl)-N-{(1R)-1-[(3P,5P)-3-(1-ethyl-1H-pyrazol-3-yl)-5-(1-methyl-1H-pyrazol-4-yl)phenyl]ethyl}benzamide
;
'Jun13567, bound form' 'C36 H44 N8 O4'  652.786 
ALA   'L-peptide linking' y ALANINE ?                      'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ?                      'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ?                      'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ?                      'C4 H7 N O4'     133.103 
CL    non-polymer         . 'CHLORIDE ION' ?                      'Cl -1'          35.453  
CYS   'L-peptide linking' y CYSTEINE ?                      'C3 H7 N O2 S'   121.158 
DTT   non-polymer         . 2,3-DIHYDROXY-1,4-DITHIOBUTANE 1,4-DITHIOTHREITOL     'C4 H10 O2 S2'   154.251 
GLN   'L-peptide linking' y GLUTAMINE ?                      'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ?                      'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ?                      'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE ?                      'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER ?                      'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE ?                      'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ?                      'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ?                      'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ?                      'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ?                      'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ?                      'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ?                      'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ?                      'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ?                      'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ?                      'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE ?                      'C5 H11 N O2'    117.146 
ZN    non-polymer         . 'ZINC ION' ?                      'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   -2  ?   ?   ?   A . n 
A 1 2   ASN 2   -1  ?   ?   ?   A . n 
A 1 3   ALA 3   0   ?   ?   ?   A . n 
A 1 4   GLU 4   1   ?   ?   ?   A . n 
A 1 5   VAL 5   2   ?   ?   ?   A . n 
A 1 6   ARG 6   3   3   ARG ARG A . n 
A 1 7   THR 7   4   4   THR THR A . n 
A 1 8   ILE 8   5   5   ILE ILE A . n 
A 1 9   LYS 9   6   6   LYS LYS A . n 
A 1 10  VAL 10  7   7   VAL VAL A . n 
A 1 11  PHE 11  8   8   PHE PHE A . n 
A 1 12  THR 12  9   9   THR THR A . n 
A 1 13  THR 13  10  10  THR THR A . n 
A 1 14  VAL 14  11  11  VAL VAL A . n 
A 1 15  ASP 15  12  12  ASP ASP A . n 
A 1 16  ASN 16  13  13  ASN ASN A . n 
A 1 17  ILE 17  14  14  ILE ILE A . n 
A 1 18  ASN 18  15  15  ASN ASN A . n 
A 1 19  LEU 19  16  16  LEU LEU A . n 
A 1 20  HIS 20  17  17  HIS HIS A . n 
A 1 21  THR 21  18  18  THR THR A . n 
A 1 22  GLN 22  19  19  GLN GLN A . n 
A 1 23  VAL 23  20  20  VAL VAL A . n 
A 1 24  VAL 24  21  21  VAL VAL A . n 
A 1 25  ASP 25  22  22  ASP ASP A . n 
A 1 26  MET 26  23  23  MET MET A . n 
A 1 27  SER 27  24  24  SER SER A . n 
A 1 28  MET 28  25  25  MET MET A . n 
A 1 29  THR 29  26  26  THR THR A . n 
A 1 30  TYR 30  27  27  TYR TYR A . n 
A 1 31  GLY 31  28  28  GLY GLY A . n 
A 1 32  GLN 32  29  29  GLN GLN A . n 
A 1 33  GLN 33  30  30  GLN GLN A . n 
A 1 34  PHE 34  31  31  PHE PHE A . n 
A 1 35  GLY 35  32  32  GLY GLY A . n 
A 1 36  PRO 36  33  33  PRO PRO A . n 
A 1 37  THR 37  34  34  THR THR A . n 
A 1 38  TYR 38  35  35  TYR TYR A . n 
A 1 39  LEU 39  36  36  LEU LEU A . n 
A 1 40  ASP 40  37  37  ASP ASP A . n 
A 1 41  GLY 41  38  38  GLY GLY A . n 
A 1 42  ALA 42  39  39  ALA ALA A . n 
A 1 43  ASP 43  40  40  ASP ASP A . n 
A 1 44  VAL 44  41  41  VAL VAL A . n 
A 1 45  THR 45  42  42  THR THR A . n 
A 1 46  LYS 46  43  43  LYS LYS A . n 
A 1 47  ILE 47  44  44  ILE ILE A . n 
A 1 48  LYS 48  45  45  LYS LYS A . n 
A 1 49  PRO 49  46  46  PRO PRO A . n 
A 1 50  HIS 50  47  47  HIS HIS A . n 
A 1 51  ASN 51  48  48  ASN ASN A . n 
A 1 52  SER 52  49  49  SER SER A . n 
A 1 53  HIS 53  50  50  HIS HIS A . n 
A 1 54  GLU 54  51  51  GLU GLU A . n 
A 1 55  GLY 55  52  52  GLY GLY A . n 
A 1 56  LYS 56  53  53  LYS LYS A . n 
A 1 57  THR 57  54  54  THR THR A . n 
A 1 58  PHE 58  55  55  PHE PHE A . n 
A 1 59  TYR 59  56  56  TYR TYR A . n 
A 1 60  VAL 60  57  57  VAL VAL A . n 
A 1 61  LEU 61  58  58  LEU LEU A . n 
A 1 62  PRO 62  59  59  PRO PRO A . n 
A 1 63  ASN 63  60  60  ASN ASN A . n 
A 1 64  ASP 64  61  61  ASP ASP A . n 
A 1 65  ASP 65  62  62  ASP ASP A . n 
A 1 66  THR 66  63  63  THR THR A . n 
A 1 67  LEU 67  64  64  LEU LEU A . n 
A 1 68  ARG 68  65  65  ARG ARG A . n 
A 1 69  VAL 69  66  66  VAL VAL A . n 
A 1 70  GLU 70  67  67  GLU GLU A . n 
A 1 71  ALA 71  68  68  ALA ALA A . n 
A 1 72  PHE 72  69  69  PHE PHE A . n 
A 1 73  GLU 73  70  70  GLU GLU A . n 
A 1 74  TYR 74  71  71  TYR TYR A . n 
A 1 75  TYR 75  72  72  TYR TYR A . n 
A 1 76  HIS 76  73  73  HIS HIS A . n 
A 1 77  THR 77  74  74  THR THR A . n 
A 1 78  THR 78  75  75  THR THR A . n 
A 1 79  ASP 79  76  76  ASP ASP A . n 
A 1 80  PRO 80  77  77  PRO PRO A . n 
A 1 81  SER 81  78  78  SER SER A . n 
A 1 82  PHE 82  79  79  PHE PHE A . n 
A 1 83  LEU 83  80  80  LEU LEU A . n 
A 1 84  GLY 84  81  81  GLY GLY A . n 
A 1 85  ARG 85  82  82  ARG ARG A . n 
A 1 86  TYR 86  83  83  TYR TYR A . n 
A 1 87  MET 87  84  84  MET MET A . n 
A 1 88  SER 88  85  85  SER SER A . n 
A 1 89  ALA 89  86  86  ALA ALA A . n 
A 1 90  LEU 90  87  87  LEU LEU A . n 
A 1 91  ASN 91  88  88  ASN ASN A . n 
A 1 92  HIS 92  89  89  HIS HIS A . n 
A 1 93  THR 93  90  90  THR THR A . n 
A 1 94  LYS 94  91  91  LYS LYS A . n 
A 1 95  LYS 95  92  92  LYS LYS A . n 
A 1 96  TRP 96  93  93  TRP TRP A . n 
A 1 97  LYS 97  94  94  LYS LYS A . n 
A 1 98  TYR 98  95  95  TYR TYR A . n 
A 1 99  PRO 99  96  96  PRO PRO A . n 
A 1 100 GLN 100 97  97  GLN GLN A . n 
A 1 101 VAL 101 98  98  VAL VAL A . n 
A 1 102 ASN 102 99  99  ASN ASN A . n 
A 1 103 GLY 103 100 100 GLY GLY A . n 
A 1 104 LEU 104 101 101 LEU LEU A . n 
A 1 105 THR 105 102 102 THR THR A . n 
A 1 106 SER 106 103 103 SER SER A . n 
A 1 107 ILE 107 104 104 ILE ILE A . n 
A 1 108 LYS 108 105 105 LYS LYS A . n 
A 1 109 TRP 109 106 106 TRP TRP A . n 
A 1 110 ALA 110 107 107 ALA ALA A . n 
A 1 111 ASP 111 108 108 ASP ASP A . n 
A 1 112 ASN 112 109 109 ASN ASN A . n 
A 1 113 ASN 113 110 110 ASN ASN A . n 
A 1 114 CYS 114 111 111 CYS CYS A . n 
A 1 115 TYR 115 112 112 TYR TYR A . n 
A 1 116 LEU 116 113 113 LEU LEU A . n 
A 1 117 ALA 117 114 114 ALA ALA A . n 
A 1 118 THR 118 115 115 THR THR A . n 
A 1 119 ALA 119 116 116 ALA ALA A . n 
A 1 120 LEU 120 117 117 LEU LEU A . n 
A 1 121 LEU 121 118 118 LEU LEU A . n 
A 1 122 THR 122 119 119 THR THR A . n 
A 1 123 LEU 123 120 120 LEU LEU A . n 
A 1 124 GLN 124 121 121 GLN GLN A . n 
A 1 125 GLN 125 122 122 GLN GLN A . n 
A 1 126 ILE 126 123 123 ILE ILE A . n 
A 1 127 GLU 127 124 124 GLU GLU A . n 
A 1 128 LEU 128 125 125 LEU LEU A . n 
A 1 129 LYS 129 126 126 LYS LYS A . n 
A 1 130 PHE 130 127 127 PHE PHE A . n 
A 1 131 ASN 131 128 128 ASN ASN A . n 
A 1 132 PRO 132 129 129 PRO PRO A . n 
A 1 133 PRO 133 130 130 PRO PRO A . n 
A 1 134 ALA 134 131 131 ALA ALA A . n 
A 1 135 LEU 135 132 132 LEU LEU A . n 
A 1 136 GLN 136 133 133 GLN GLN A . n 
A 1 137 ASP 137 134 134 ASP ASP A . n 
A 1 138 ALA 138 135 135 ALA ALA A . n 
A 1 139 TYR 139 136 136 TYR TYR A . n 
A 1 140 TYR 140 137 137 TYR TYR A . n 
A 1 141 ARG 141 138 138 ARG ARG A . n 
A 1 142 ALA 142 139 139 ALA ALA A . n 
A 1 143 ARG 143 140 140 ARG ARG A . n 
A 1 144 ALA 144 141 141 ALA ALA A . n 
A 1 145 GLY 145 142 142 GLY GLY A . n 
A 1 146 GLU 146 143 143 GLU GLU A . n 
A 1 147 ALA 147 144 144 ALA ALA A . n 
A 1 148 ALA 148 145 145 ALA ALA A . n 
A 1 149 ASN 149 146 146 ASN ASN A . n 
A 1 150 PHE 150 147 147 PHE PHE A . n 
A 1 151 CYS 151 148 148 CYS CYS A . n 
A 1 152 ALA 152 149 149 ALA ALA A . n 
A 1 153 LEU 153 150 150 LEU LEU A . n 
A 1 154 ILE 154 151 151 ILE ILE A . n 
A 1 155 LEU 155 152 152 LEU LEU A . n 
A 1 156 ALA 156 153 153 ALA ALA A . n 
A 1 157 TYR 157 154 154 TYR TYR A . n 
A 1 158 CYS 158 155 155 CYS CYS A . n 
A 1 159 ASN 159 156 156 ASN ASN A . n 
A 1 160 LYS 160 157 157 LYS LYS A . n 
A 1 161 THR 161 158 158 THR THR A . n 
A 1 162 VAL 162 159 159 VAL VAL A . n 
A 1 163 GLY 163 160 160 GLY GLY A . n 
A 1 164 GLU 164 161 161 GLU GLU A . n 
A 1 165 LEU 165 162 162 LEU LEU A . n 
A 1 166 GLY 166 163 163 GLY GLY A . n 
A 1 167 ASP 167 164 164 ASP ASP A . n 
A 1 168 VAL 168 165 165 VAL VAL A . n 
A 1 169 ARG 169 166 166 ARG ARG A . n 
A 1 170 GLU 170 167 167 GLU GLU A . n 
A 1 171 THR 171 168 168 THR THR A . n 
A 1 172 MET 172 169 169 MET MET A . n 
A 1 173 SER 173 170 170 SER SER A . n 
A 1 174 TYR 174 171 171 TYR TYR A . n 
A 1 175 LEU 175 172 172 LEU LEU A . n 
A 1 176 PHE 176 173 173 PHE PHE A . n 
A 1 177 GLN 177 174 174 GLN GLN A . n 
A 1 178 HIS 178 175 175 HIS HIS A . n 
A 1 179 ALA 179 176 176 ALA ALA A . n 
A 1 180 ASN 180 177 177 ASN ASN A . n 
A 1 181 LEU 181 178 178 LEU LEU A . n 
A 1 182 ASP 182 179 179 ASP ASP A . n 
A 1 183 SER 183 180 180 SER SER A . n 
A 1 184 CYS 184 181 181 CYS CYS A . n 
A 1 185 LYS 185 182 182 LYS LYS A . n 
A 1 186 ARG 186 183 183 ARG ARG A . n 
A 1 187 VAL 187 184 184 VAL VAL A . n 
A 1 188 LEU 188 185 185 LEU LEU A . n 
A 1 189 ASN 189 186 186 ASN ASN A . n 
A 1 190 VAL 190 187 187 VAL VAL A . n 
A 1 191 VAL 191 188 188 VAL VAL A . n 
A 1 192 CYS 192 189 189 CYS CYS A . n 
A 1 193 LYS 193 190 190 LYS LYS A . n 
A 1 194 THR 194 191 191 THR THR A . n 
A 1 195 CYS 195 192 192 CYS CYS A . n 
A 1 196 GLY 196 193 193 GLY GLY A . n 
A 1 197 GLN 197 194 194 GLN GLN A . n 
A 1 198 GLN 198 195 195 GLN GLN A . n 
A 1 199 GLN 199 196 196 GLN GLN A . n 
A 1 200 THR 200 197 197 THR THR A . n 
A 1 201 THR 201 198 198 THR THR A . n 
A 1 202 LEU 202 199 199 LEU LEU A . n 
A 1 203 LYS 203 200 200 LYS LYS A . n 
A 1 204 GLY 204 201 201 GLY GLY A . n 
A 1 205 VAL 205 202 202 VAL VAL A . n 
A 1 206 GLU 206 203 203 GLU GLU A . n 
A 1 207 ALA 207 204 204 ALA ALA A . n 
A 1 208 VAL 208 205 205 VAL VAL A . n 
A 1 209 MET 209 206 206 MET MET A . n 
A 1 210 TYR 210 207 207 TYR TYR A . n 
A 1 211 MET 211 208 208 MET MET A . n 
A 1 212 GLY 212 209 209 GLY GLY A . n 
A 1 213 THR 213 210 210 THR THR A . n 
A 1 214 LEU 214 211 211 LEU LEU A . n 
A 1 215 SER 215 212 212 SER SER A . n 
A 1 216 TYR 216 213 213 TYR TYR A . n 
A 1 217 GLU 217 214 214 GLU GLU A . n 
A 1 218 GLN 218 215 215 GLN GLN A . n 
A 1 219 PHE 219 216 216 PHE PHE A . n 
A 1 220 LYS 220 217 217 LYS LYS A . n 
A 1 221 LYS 221 218 218 LYS LYS A . n 
A 1 222 GLY 222 219 219 GLY GLY A . n 
A 1 223 VAL 223 220 220 VAL VAL A . n 
A 1 224 GLN 224 221 221 GLN GLN A . n 
A 1 225 ILE 225 222 222 ILE ILE A . n 
A 1 226 PRO 226 223 223 PRO PRO A . n 
A 1 227 CYS 227 224 224 CYS CYS A . n 
A 1 228 THR 228 225 225 THR THR A . n 
A 1 229 CYS 229 226 226 CYS CYS A . n 
A 1 230 GLY 230 227 227 GLY GLY A . n 
A 1 231 LYS 231 228 228 LYS LYS A . n 
A 1 232 GLN 232 229 229 GLN GLN A . n 
A 1 233 ALA 233 230 230 ALA ALA A . n 
A 1 234 THR 234 231 231 THR THR A . n 
A 1 235 LYS 235 232 232 LYS LYS A . n 
A 1 236 TYR 236 233 233 TYR TYR A . n 
A 1 237 LEU 237 234 234 LEU LEU A . n 
A 1 238 VAL 238 235 235 VAL VAL A . n 
A 1 239 GLN 239 236 236 GLN GLN A . n 
A 1 240 GLN 240 237 237 GLN GLN A . n 
A 1 241 GLU 241 238 238 GLU GLU A . n 
A 1 242 SER 242 239 239 SER SER A . n 
A 1 243 PRO 243 240 240 PRO PRO A . n 
A 1 244 PHE 244 241 241 PHE PHE A . n 
A 1 245 VAL 245 242 242 VAL VAL A . n 
A 1 246 MET 246 243 243 MET MET A . n 
A 1 247 MET 247 244 244 MET MET A . n 
A 1 248 SER 248 245 245 SER SER A . n 
A 1 249 ALA 249 246 246 ALA ALA A . n 
A 1 250 PRO 250 247 247 PRO PRO A . n 
A 1 251 PRO 251 248 248 PRO PRO A . n 
A 1 252 ALA 252 249 249 ALA ALA A . n 
A 1 253 GLN 253 250 250 GLN GLN A . n 
A 1 254 TYR 254 251 251 TYR TYR A . n 
A 1 255 GLU 255 252 252 GLU GLU A . n 
A 1 256 LEU 256 253 253 LEU LEU A . n 
A 1 257 LYS 257 254 254 LYS LYS A . n 
A 1 258 HIS 258 255 255 HIS HIS A . n 
A 1 259 GLY 259 256 256 GLY GLY A . n 
A 1 260 THR 260 257 257 THR THR A . n 
A 1 261 PHE 261 258 258 PHE PHE A . n 
A 1 262 THR 262 259 259 THR THR A . n 
A 1 263 CYS 263 260 260 CYS CYS A . n 
A 1 264 ALA 264 261 261 ALA ALA A . n 
A 1 265 SER 265 262 262 SER SER A . n 
A 1 266 GLU 266 263 263 GLU GLU A . n 
A 1 267 TYR 267 264 264 TYR TYR A . n 
A 1 268 THR 268 265 265 THR THR A . n 
A 1 269 GLY 269 266 266 GLY GLY A . n 
A 1 270 ASN 270 267 267 ASN ASN A . n 
A 1 271 TYR 271 268 268 TYR TYR A . n 
A 1 272 GLN 272 269 269 GLN GLN A . n 
A 1 273 CYS 273 270 270 CYS CYS A . n 
A 1 274 GLY 274 271 271 GLY GLY A . n 
A 1 275 HIS 275 272 272 HIS HIS A . n 
A 1 276 TYR 276 273 273 TYR TYR A . n 
A 1 277 LYS 277 274 274 LYS LYS A . n 
A 1 278 HIS 278 275 275 HIS HIS A . n 
A 1 279 ILE 279 276 276 ILE ILE A . n 
A 1 280 THR 280 277 277 THR THR A . n 
A 1 281 SER 281 278 278 SER SER A . n 
A 1 282 LYS 282 279 279 LYS LYS A . n 
A 1 283 GLU 283 280 280 GLU GLU A . n 
A 1 284 THR 284 281 281 THR THR A . n 
A 1 285 LEU 285 282 282 LEU LEU A . n 
A 1 286 TYR 286 283 283 TYR TYR A . n 
A 1 287 CYS 287 284 284 CYS CYS A . n 
A 1 288 ILE 288 285 285 ILE ILE A . n 
A 1 289 ASP 289 286 286 ASP ASP A . n 
A 1 290 GLY 290 287 287 GLY GLY A . n 
A 1 291 ALA 291 288 288 ALA ALA A . n 
A 1 292 LEU 292 289 289 LEU LEU A . n 
A 1 293 LEU 293 290 290 LEU LEU A . n 
A 1 294 THR 294 291 291 THR THR A . n 
A 1 295 LYS 295 292 292 LYS LYS A . n 
A 1 296 SER 296 293 293 SER SER A . n 
A 1 297 SER 297 294 294 SER SER A . n 
A 1 298 GLU 298 295 295 GLU GLU A . n 
A 1 299 TYR 299 296 296 TYR TYR A . n 
A 1 300 LYS 300 297 297 LYS LYS A . n 
A 1 301 GLY 301 298 298 GLY GLY A . n 
A 1 302 PRO 302 299 299 PRO PRO A . n 
A 1 303 ILE 303 300 300 ILE ILE A . n 
A 1 304 THR 304 301 301 THR THR A . n 
A 1 305 ASP 305 302 302 ASP ASP A . n 
A 1 306 VAL 306 303 303 VAL VAL A . n 
A 1 307 PHE 307 304 304 PHE PHE A . n 
A 1 308 TYR 308 305 305 TYR TYR A . n 
A 1 309 LYS 309 306 306 LYS LYS A . n 
A 1 310 GLU 310 307 307 GLU GLU A . n 
A 1 311 ASN 311 308 308 ASN ASN A . n 
A 1 312 SER 312 309 309 SER SER A . n 
A 1 313 TYR 313 310 310 TYR TYR A . n 
A 1 314 THR 314 311 311 THR THR A . n 
A 1 315 THR 315 312 312 THR THR A . n 
A 1 316 THR 316 313 313 THR THR A . n 
A 1 317 ILE 317 314 314 ILE ILE A . n 
A 1 318 LYS 318 315 315 LYS LYS A . n 
B 1 1   SER 1   -2  ?   ?   ?   B . n 
B 1 2   ASN 2   -1  ?   ?   ?   B . n 
B 1 3   ALA 3   0   ?   ?   ?   B . n 
B 1 4   GLU 4   1   ?   ?   ?   B . n 
B 1 5   VAL 5   2   ?   ?   ?   B . n 
B 1 6   ARG 6   3   ?   ?   ?   B . n 
B 1 7   THR 7   4   4   THR THR B . n 
B 1 8   ILE 8   5   5   ILE ILE B . n 
B 1 9   LYS 9   6   6   LYS LYS B . n 
B 1 10  VAL 10  7   7   VAL VAL B . n 
B 1 11  PHE 11  8   8   PHE PHE B . n 
B 1 12  THR 12  9   9   THR THR B . n 
B 1 13  THR 13  10  10  THR THR B . n 
B 1 14  VAL 14  11  11  VAL VAL B . n 
B 1 15  ASP 15  12  12  ASP ASP B . n 
B 1 16  ASN 16  13  13  ASN ASN B . n 
B 1 17  ILE 17  14  14  ILE ILE B . n 
B 1 18  ASN 18  15  15  ASN ASN B . n 
B 1 19  LEU 19  16  16  LEU LEU B . n 
B 1 20  HIS 20  17  17  HIS HIS B . n 
B 1 21  THR 21  18  18  THR THR B . n 
B 1 22  GLN 22  19  19  GLN GLN B . n 
B 1 23  VAL 23  20  20  VAL VAL B . n 
B 1 24  VAL 24  21  21  VAL VAL B . n 
B 1 25  ASP 25  22  22  ASP ASP B . n 
B 1 26  MET 26  23  23  MET MET B . n 
B 1 27  SER 27  24  24  SER SER B . n 
B 1 28  MET 28  25  25  MET MET B . n 
B 1 29  THR 29  26  26  THR THR B . n 
B 1 30  TYR 30  27  27  TYR TYR B . n 
B 1 31  GLY 31  28  28  GLY GLY B . n 
B 1 32  GLN 32  29  29  GLN GLN B . n 
B 1 33  GLN 33  30  30  GLN GLN B . n 
B 1 34  PHE 34  31  31  PHE PHE B . n 
B 1 35  GLY 35  32  32  GLY GLY B . n 
B 1 36  PRO 36  33  33  PRO PRO B . n 
B 1 37  THR 37  34  34  THR THR B . n 
B 1 38  TYR 38  35  35  TYR TYR B . n 
B 1 39  LEU 39  36  36  LEU LEU B . n 
B 1 40  ASP 40  37  37  ASP ASP B . n 
B 1 41  GLY 41  38  38  GLY GLY B . n 
B 1 42  ALA 42  39  39  ALA ALA B . n 
B 1 43  ASP 43  40  40  ASP ASP B . n 
B 1 44  VAL 44  41  41  VAL VAL B . n 
B 1 45  THR 45  42  42  THR THR B . n 
B 1 46  LYS 46  43  43  LYS LYS B . n 
B 1 47  ILE 47  44  44  ILE ILE B . n 
B 1 48  LYS 48  45  45  LYS LYS B . n 
B 1 49  PRO 49  46  46  PRO PRO B . n 
B 1 50  HIS 50  47  47  HIS HIS B . n 
B 1 51  ASN 51  48  48  ASN ASN B . n 
B 1 52  SER 52  49  49  SER SER B . n 
B 1 53  HIS 53  50  50  HIS HIS B . n 
B 1 54  GLU 54  51  51  GLU GLU B . n 
B 1 55  GLY 55  52  52  GLY GLY B . n 
B 1 56  LYS 56  53  53  LYS LYS B . n 
B 1 57  THR 57  54  54  THR THR B . n 
B 1 58  PHE 58  55  55  PHE PHE B . n 
B 1 59  TYR 59  56  56  TYR TYR B . n 
B 1 60  VAL 60  57  57  VAL VAL B . n 
B 1 61  LEU 61  58  58  LEU LEU B . n 
B 1 62  PRO 62  59  59  PRO PRO B . n 
B 1 63  ASN 63  60  60  ASN ASN B . n 
B 1 64  ASP 64  61  61  ASP ASP B . n 
B 1 65  ASP 65  62  62  ASP ASP B . n 
B 1 66  THR 66  63  63  THR THR B . n 
B 1 67  LEU 67  64  64  LEU LEU B . n 
B 1 68  ARG 68  65  65  ARG ARG B . n 
B 1 69  VAL 69  66  66  VAL VAL B . n 
B 1 70  GLU 70  67  67  GLU GLU B . n 
B 1 71  ALA 71  68  68  ALA ALA B . n 
B 1 72  PHE 72  69  69  PHE PHE B . n 
B 1 73  GLU 73  70  70  GLU GLU B . n 
B 1 74  TYR 74  71  71  TYR TYR B . n 
B 1 75  TYR 75  72  72  TYR TYR B . n 
B 1 76  HIS 76  73  73  HIS HIS B . n 
B 1 77  THR 77  74  74  THR THR B . n 
B 1 78  THR 78  75  75  THR THR B . n 
B 1 79  ASP 79  76  76  ASP ASP B . n 
B 1 80  PRO 80  77  77  PRO PRO B . n 
B 1 81  SER 81  78  78  SER SER B . n 
B 1 82  PHE 82  79  79  PHE PHE B . n 
B 1 83  LEU 83  80  80  LEU LEU B . n 
B 1 84  GLY 84  81  81  GLY GLY B . n 
B 1 85  ARG 85  82  82  ARG ARG B . n 
B 1 86  TYR 86  83  83  TYR TYR B . n 
B 1 87  MET 87  84  84  MET MET B . n 
B 1 88  SER 88  85  85  SER SER B . n 
B 1 89  ALA 89  86  86  ALA ALA B . n 
B 1 90  LEU 90  87  87  LEU LEU B . n 
B 1 91  ASN 91  88  88  ASN ASN B . n 
B 1 92  HIS 92  89  89  HIS HIS B . n 
B 1 93  THR 93  90  90  THR THR B . n 
B 1 94  LYS 94  91  91  LYS LYS B . n 
B 1 95  LYS 95  92  92  LYS LYS B . n 
B 1 96  TRP 96  93  93  TRP TRP B . n 
B 1 97  LYS 97  94  94  LYS LYS B . n 
B 1 98  TYR 98  95  95  TYR TYR B . n 
B 1 99  PRO 99  96  96  PRO PRO B . n 
B 1 100 GLN 100 97  97  GLN GLN B . n 
B 1 101 VAL 101 98  98  VAL VAL B . n 
B 1 102 ASN 102 99  99  ASN ASN B . n 
B 1 103 GLY 103 100 100 GLY GLY B . n 
B 1 104 LEU 104 101 101 LEU LEU B . n 
B 1 105 THR 105 102 102 THR THR B . n 
B 1 106 SER 106 103 103 SER SER B . n 
B 1 107 ILE 107 104 104 ILE ILE B . n 
B 1 108 LYS 108 105 105 LYS LYS B . n 
B 1 109 TRP 109 106 106 TRP TRP B . n 
B 1 110 ALA 110 107 107 ALA ALA B . n 
B 1 111 ASP 111 108 108 ASP ASP B . n 
B 1 112 ASN 112 109 109 ASN ASN B . n 
B 1 113 ASN 113 110 110 ASN ASN B . n 
B 1 114 CYS 114 111 111 CYS CYS B . n 
B 1 115 TYR 115 112 112 TYR TYR B . n 
B 1 116 LEU 116 113 113 LEU LEU B . n 
B 1 117 ALA 117 114 114 ALA ALA B . n 
B 1 118 THR 118 115 115 THR THR B . n 
B 1 119 ALA 119 116 116 ALA ALA B . n 
B 1 120 LEU 120 117 117 LEU LEU B . n 
B 1 121 LEU 121 118 118 LEU LEU B . n 
B 1 122 THR 122 119 119 THR THR B . n 
B 1 123 LEU 123 120 120 LEU LEU B . n 
B 1 124 GLN 124 121 121 GLN GLN B . n 
B 1 125 GLN 125 122 122 GLN GLN B . n 
B 1 126 ILE 126 123 123 ILE ILE B . n 
B 1 127 GLU 127 124 124 GLU GLU B . n 
B 1 128 LEU 128 125 125 LEU LEU B . n 
B 1 129 LYS 129 126 126 LYS LYS B . n 
B 1 130 PHE 130 127 127 PHE PHE B . n 
B 1 131 ASN 131 128 128 ASN ASN B . n 
B 1 132 PRO 132 129 129 PRO PRO B . n 
B 1 133 PRO 133 130 130 PRO PRO B . n 
B 1 134 ALA 134 131 131 ALA ALA B . n 
B 1 135 LEU 135 132 132 LEU LEU B . n 
B 1 136 GLN 136 133 133 GLN GLN B . n 
B 1 137 ASP 137 134 134 ASP ASP B . n 
B 1 138 ALA 138 135 135 ALA ALA B . n 
B 1 139 TYR 139 136 136 TYR TYR B . n 
B 1 140 TYR 140 137 137 TYR TYR B . n 
B 1 141 ARG 141 138 138 ARG ARG B . n 
B 1 142 ALA 142 139 139 ALA ALA B . n 
B 1 143 ARG 143 140 140 ARG ARG B . n 
B 1 144 ALA 144 141 141 ALA ALA B . n 
B 1 145 GLY 145 142 142 GLY GLY B . n 
B 1 146 GLU 146 143 143 GLU GLU B . n 
B 1 147 ALA 147 144 144 ALA ALA B . n 
B 1 148 ALA 148 145 145 ALA ALA B . n 
B 1 149 ASN 149 146 146 ASN ASN B . n 
B 1 150 PHE 150 147 147 PHE PHE B . n 
B 1 151 CYS 151 148 148 CYS CYS B . n 
B 1 152 ALA 152 149 149 ALA ALA B . n 
B 1 153 LEU 153 150 150 LEU LEU B . n 
B 1 154 ILE 154 151 151 ILE ILE B . n 
B 1 155 LEU 155 152 152 LEU LEU B . n 
B 1 156 ALA 156 153 153 ALA ALA B . n 
B 1 157 TYR 157 154 154 TYR TYR B . n 
B 1 158 CYS 158 155 155 CYS CYS B . n 
B 1 159 ASN 159 156 156 ASN ASN B . n 
B 1 160 LYS 160 157 157 LYS LYS B . n 
B 1 161 THR 161 158 158 THR THR B . n 
B 1 162 VAL 162 159 159 VAL VAL B . n 
B 1 163 GLY 163 160 160 GLY GLY B . n 
B 1 164 GLU 164 161 161 GLU GLU B . n 
B 1 165 LEU 165 162 162 LEU LEU B . n 
B 1 166 GLY 166 163 163 GLY GLY B . n 
B 1 167 ASP 167 164 164 ASP ASP B . n 
B 1 168 VAL 168 165 165 VAL VAL B . n 
B 1 169 ARG 169 166 166 ARG ARG B . n 
B 1 170 GLU 170 167 167 GLU GLU B . n 
B 1 171 THR 171 168 168 THR THR B . n 
B 1 172 MET 172 169 169 MET MET B . n 
B 1 173 SER 173 170 170 SER SER B . n 
B 1 174 TYR 174 171 171 TYR TYR B . n 
B 1 175 LEU 175 172 172 LEU LEU B . n 
B 1 176 PHE 176 173 173 PHE PHE B . n 
B 1 177 GLN 177 174 174 GLN GLN B . n 
B 1 178 HIS 178 175 175 HIS HIS B . n 
B 1 179 ALA 179 176 176 ALA ALA B . n 
B 1 180 ASN 180 177 177 ASN ASN B . n 
B 1 181 LEU 181 178 178 LEU LEU B . n 
B 1 182 ASP 182 179 179 ASP ASP B . n 
B 1 183 SER 183 180 180 SER SER B . n 
B 1 184 CYS 184 181 181 CYS CYS B . n 
B 1 185 LYS 185 182 182 LYS LYS B . n 
B 1 186 ARG 186 183 183 ARG ARG B . n 
B 1 187 VAL 187 184 184 VAL VAL B . n 
B 1 188 LEU 188 185 185 LEU LEU B . n 
B 1 189 ASN 189 186 ?   ?   ?   B . n 
B 1 190 VAL 190 187 ?   ?   ?   B . n 
B 1 191 VAL 191 188 ?   ?   ?   B . n 
B 1 192 CYS 192 189 ?   ?   ?   B . n 
B 1 193 LYS 193 190 ?   ?   ?   B . n 
B 1 194 THR 194 191 ?   ?   ?   B . n 
B 1 195 CYS 195 192 ?   ?   ?   B . n 
B 1 196 GLY 196 193 ?   ?   ?   B . n 
B 1 197 GLN 197 194 ?   ?   ?   B . n 
B 1 198 GLN 198 195 ?   ?   ?   B . n 
B 1 199 GLN 199 196 ?   ?   ?   B . n 
B 1 200 THR 200 197 ?   ?   ?   B . n 
B 1 201 THR 201 198 198 THR THR B . n 
B 1 202 LEU 202 199 199 LEU LEU B . n 
B 1 203 LYS 203 200 200 LYS LYS B . n 
B 1 204 GLY 204 201 201 GLY GLY B . n 
B 1 205 VAL 205 202 202 VAL VAL B . n 
B 1 206 GLU 206 203 203 GLU GLU B . n 
B 1 207 ALA 207 204 204 ALA ALA B . n 
B 1 208 VAL 208 205 205 VAL VAL B . n 
B 1 209 MET 209 206 206 MET MET B . n 
B 1 210 TYR 210 207 207 TYR TYR B . n 
B 1 211 MET 211 208 208 MET MET B . n 
B 1 212 GLY 212 209 209 GLY GLY B . n 
B 1 213 THR 213 210 210 THR THR B . n 
B 1 214 LEU 214 211 211 LEU LEU B . n 
B 1 215 SER 215 212 212 SER SER B . n 
B 1 216 TYR 216 213 213 TYR TYR B . n 
B 1 217 GLU 217 214 214 GLU GLU B . n 
B 1 218 GLN 218 215 215 GLN GLN B . n 
B 1 219 PHE 219 216 216 PHE PHE B . n 
B 1 220 LYS 220 217 217 LYS LYS B . n 
B 1 221 LYS 221 218 218 LYS LYS B . n 
B 1 222 GLY 222 219 ?   ?   ?   B . n 
B 1 223 VAL 223 220 ?   ?   ?   B . n 
B 1 224 GLN 224 221 ?   ?   ?   B . n 
B 1 225 ILE 225 222 ?   ?   ?   B . n 
B 1 226 PRO 226 223 ?   ?   ?   B . n 
B 1 227 CYS 227 224 ?   ?   ?   B . n 
B 1 228 THR 228 225 ?   ?   ?   B . n 
B 1 229 CYS 229 226 ?   ?   ?   B . n 
B 1 230 GLY 230 227 ?   ?   ?   B . n 
B 1 231 LYS 231 228 ?   ?   ?   B . n 
B 1 232 GLN 232 229 ?   ?   ?   B . n 
B 1 233 ALA 233 230 ?   ?   ?   B . n 
B 1 234 THR 234 231 231 THR THR B . n 
B 1 235 LYS 235 232 232 LYS LYS B . n 
B 1 236 TYR 236 233 233 TYR TYR B . n 
B 1 237 LEU 237 234 234 LEU LEU B . n 
B 1 238 VAL 238 235 235 VAL VAL B . n 
B 1 239 GLN 239 236 236 GLN GLN B . n 
B 1 240 GLN 240 237 237 GLN GLN B . n 
B 1 241 GLU 241 238 238 GLU GLU B . n 
B 1 242 SER 242 239 239 SER SER B . n 
B 1 243 PRO 243 240 240 PRO PRO B . n 
B 1 244 PHE 244 241 241 PHE PHE B . n 
B 1 245 VAL 245 242 242 VAL VAL B . n 
B 1 246 MET 246 243 243 MET MET B . n 
B 1 247 MET 247 244 244 MET MET B . n 
B 1 248 SER 248 245 245 SER SER B . n 
B 1 249 ALA 249 246 246 ALA ALA B . n 
B 1 250 PRO 250 247 247 PRO PRO B . n 
B 1 251 PRO 251 248 248 PRO PRO B . n 
B 1 252 ALA 252 249 249 ALA ALA B . n 
B 1 253 GLN 253 250 250 GLN GLN B . n 
B 1 254 TYR 254 251 251 TYR TYR B . n 
B 1 255 GLU 255 252 252 GLU GLU B . n 
B 1 256 LEU 256 253 253 LEU LEU B . n 
B 1 257 LYS 257 254 254 LYS LYS B . n 
B 1 258 HIS 258 255 255 HIS HIS B . n 
B 1 259 GLY 259 256 256 GLY GLY B . n 
B 1 260 THR 260 257 257 THR THR B . n 
B 1 261 PHE 261 258 258 PHE PHE B . n 
B 1 262 THR 262 259 259 THR THR B . n 
B 1 263 CYS 263 260 260 CYS CYS B . n 
B 1 264 ALA 264 261 261 ALA ALA B . n 
B 1 265 SER 265 262 262 SER SER B . n 
B 1 266 GLU 266 263 263 GLU GLU B . n 
B 1 267 TYR 267 264 264 TYR TYR B . n 
B 1 268 THR 268 265 265 THR THR B . n 
B 1 269 GLY 269 266 266 GLY GLY B . n 
B 1 270 ASN 270 267 267 ASN ASN B . n 
B 1 271 TYR 271 268 268 TYR TYR B . n 
B 1 272 GLN 272 269 269 GLN GLN B . n 
B 1 273 CYS 273 270 270 CYS CYS B . n 
B 1 274 GLY 274 271 271 GLY GLY B . n 
B 1 275 HIS 275 272 272 HIS HIS B . n 
B 1 276 TYR 276 273 273 TYR TYR B . n 
B 1 277 LYS 277 274 274 LYS LYS B . n 
B 1 278 HIS 278 275 275 HIS HIS B . n 
B 1 279 ILE 279 276 276 ILE ILE B . n 
B 1 280 THR 280 277 277 THR THR B . n 
B 1 281 SER 281 278 278 SER SER B . n 
B 1 282 LYS 282 279 279 LYS LYS B . n 
B 1 283 GLU 283 280 280 GLU GLU B . n 
B 1 284 THR 284 281 281 THR THR B . n 
B 1 285 LEU 285 282 282 LEU LEU B . n 
B 1 286 TYR 286 283 283 TYR TYR B . n 
B 1 287 CYS 287 284 284 CYS CYS B . n 
B 1 288 ILE 288 285 285 ILE ILE B . n 
B 1 289 ASP 289 286 286 ASP ASP B . n 
B 1 290 GLY 290 287 287 GLY GLY B . n 
B 1 291 ALA 291 288 288 ALA ALA B . n 
B 1 292 LEU 292 289 289 LEU LEU B . n 
B 1 293 LEU 293 290 290 LEU LEU B . n 
B 1 294 THR 294 291 291 THR THR B . n 
B 1 295 LYS 295 292 292 LYS LYS B . n 
B 1 296 SER 296 293 293 SER SER B . n 
B 1 297 SER 297 294 294 SER SER B . n 
B 1 298 GLU 298 295 295 GLU GLU B . n 
B 1 299 TYR 299 296 296 TYR TYR B . n 
B 1 300 LYS 300 297 297 LYS LYS B . n 
B 1 301 GLY 301 298 298 GLY GLY B . n 
B 1 302 PRO 302 299 299 PRO PRO B . n 
B 1 303 ILE 303 300 300 ILE ILE B . n 
B 1 304 THR 304 301 301 THR THR B . n 
B 1 305 ASP 305 302 302 ASP ASP B . n 
B 1 306 VAL 306 303 303 VAL VAL B . n 
B 1 307 PHE 307 304 304 PHE PHE B . n 
B 1 308 TYR 308 305 305 TYR TYR B . n 
B 1 309 LYS 309 306 306 LYS LYS B . n 
B 1 310 GLU 310 307 307 GLU GLU B . n 
B 1 311 ASN 311 308 308 ASN ASN B . n 
B 1 312 SER 312 309 309 SER SER B . n 
B 1 313 TYR 313 310 310 TYR TYR B . n 
B 1 314 THR 314 311 311 THR THR B . n 
B 1 315 THR 315 312 312 THR THR B . n 
B 1 316 THR 316 313 ?   ?   ?   B . n 
B 1 317 ILE 317 314 ?   ?   ?   B . n 
B 1 318 LYS 318 315 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1A6J 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1A6J 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 A1A6J 1  401 401 A1A6J I34 A . 
D 3 DTT   1  402 402 DTT   DTT A . 
E 4 ZN    1  403 2   ZN    ZN  A . 
F 4 ZN    1  404 4   ZN    ZN  A . 
G 4 ZN    1  405 11  ZN    ZN  A . 
H 4 ZN    1  406 16  ZN    ZN  A . 
I 4 ZN    1  407 19  ZN    ZN  A . 
J 5 CL    1  408 1   CL    CL  A . 
K 5 CL    1  409 2   CL    CL  A . 
L 5 CL    1  410 3   CL    CL  A . 
M 5 CL    1  411 7   CL    CL  A . 
N 5 CL    1  412 10  CL    CL  A . 
O 2 A1A6J 1  401 401 A1A6J I34 B . 
P 4 ZN    1  402 5   ZN    ZN  B . 
Q 4 ZN    1  403 12  ZN    ZN  B . 
R 4 ZN    1  404 13  ZN    ZN  B . 
S 4 ZN    1  405 15  ZN    ZN  B . 
T 4 ZN    1  406 18  ZN    ZN  B . 
U 5 CL    1  407 4   CL    CL  B . 
V 5 CL    1  408 5   CL    CL  B . 
W 5 CL    1  409 8   CL    CL  B . 
X 5 CL    1  410 9   CL    CL  B . 
Y 6 HOH   1  501 75  HOH   HOH A . 
Y 6 HOH   2  502 31  HOH   HOH A . 
Y 6 HOH   3  503 76  HOH   HOH A . 
Y 6 HOH   4  504 9   HOH   HOH A . 
Y 6 HOH   5  505 100 HOH   HOH A . 
Y 6 HOH   6  506 58  HOH   HOH A . 
Y 6 HOH   7  507 111 HOH   HOH A . 
Y 6 HOH   8  508 81  HOH   HOH A . 
Y 6 HOH   9  509 77  HOH   HOH A . 
Y 6 HOH   10 510 7   HOH   HOH A . 
Y 6 HOH   11 511 40  HOH   HOH A . 
Y 6 HOH   12 512 51  HOH   HOH A . 
Y 6 HOH   13 513 11  HOH   HOH A . 
Y 6 HOH   14 514 2   HOH   HOH A . 
Y 6 HOH   15 515 10  HOH   HOH A . 
Y 6 HOH   16 516 8   HOH   HOH A . 
Y 6 HOH   17 517 15  HOH   HOH A . 
Y 6 HOH   18 518 99  HOH   HOH A . 
Y 6 HOH   19 519 5   HOH   HOH A . 
Y 6 HOH   20 520 16  HOH   HOH A . 
Y 6 HOH   21 521 30  HOH   HOH A . 
Y 6 HOH   22 522 52  HOH   HOH A . 
Y 6 HOH   23 523 88  HOH   HOH A . 
Y 6 HOH   24 524 107 HOH   HOH A . 
Y 6 HOH   25 525 23  HOH   HOH A . 
Y 6 HOH   26 526 1   HOH   HOH A . 
Y 6 HOH   27 527 91  HOH   HOH A . 
Y 6 HOH   28 528 48  HOH   HOH A . 
Y 6 HOH   29 529 87  HOH   HOH A . 
Y 6 HOH   30 530 19  HOH   HOH A . 
Y 6 HOH   31 531 90  HOH   HOH A . 
Y 6 HOH   32 532 6   HOH   HOH A . 
Y 6 HOH   33 533 82  HOH   HOH A . 
Y 6 HOH   34 534 26  HOH   HOH A . 
Y 6 HOH   35 535 80  HOH   HOH A . 
Y 6 HOH   36 536 92  HOH   HOH A . 
Y 6 HOH   37 537 84  HOH   HOH A . 
Y 6 HOH   38 538 79  HOH   HOH A . 
Y 6 HOH   39 539 44  HOH   HOH A . 
Y 6 HOH   40 540 14  HOH   HOH A . 
Y 6 HOH   41 541 20  HOH   HOH A . 
Y 6 HOH   42 542 13  HOH   HOH A . 
Y 6 HOH   43 543 12  HOH   HOH A . 
Y 6 HOH   44 544 108 HOH   HOH A . 
Y 6 HOH   45 545 43  HOH   HOH A . 
Y 6 HOH   46 546 55  HOH   HOH A . 
Y 6 HOH   47 547 35  HOH   HOH A . 
Y 6 HOH   48 548 86  HOH   HOH A . 
Y 6 HOH   49 549 50  HOH   HOH A . 
Y 6 HOH   50 550 85  HOH   HOH A . 
Y 6 HOH   51 551 49  HOH   HOH A . 
Y 6 HOH   52 552 45  HOH   HOH A . 
Y 6 HOH   53 553 17  HOH   HOH A . 
Y 6 HOH   54 554 42  HOH   HOH A . 
Y 6 HOH   55 555 24  HOH   HOH A . 
Y 6 HOH   56 556 41  HOH   HOH A . 
Y 6 HOH   57 557 95  HOH   HOH A . 
Y 6 HOH   58 558 72  HOH   HOH A . 
Y 6 HOH   59 559 39  HOH   HOH A . 
Z 6 HOH   1  501 21  HOH   HOH B . 
Z 6 HOH   2  502 32  HOH   HOH B . 
Z 6 HOH   3  503 78  HOH   HOH B . 
Z 6 HOH   4  504 29  HOH   HOH B . 
Z 6 HOH   5  505 46  HOH   HOH B . 
Z 6 HOH   6  506 4   HOH   HOH B . 
Z 6 HOH   7  507 110 HOH   HOH B . 
Z 6 HOH   8  508 96  HOH   HOH B . 
Z 6 HOH   9  509 25  HOH   HOH B . 
Z 6 HOH   10 510 18  HOH   HOH B . 
Z 6 HOH   11 511 27  HOH   HOH B . 
Z 6 HOH   12 512 73  HOH   HOH B . 
Z 6 HOH   13 513 54  HOH   HOH B . 
Z 6 HOH   14 514 38  HOH   HOH B . 
Z 6 HOH   15 515 37  HOH   HOH B . 
Z 6 HOH   16 516 57  HOH   HOH B . 
Z 6 HOH   17 517 94  HOH   HOH B . 
Z 6 HOH   18 518 89  HOH   HOH B . 
Z 6 HOH   19 519 33  HOH   HOH B . 
Z 6 HOH   20 520 71  HOH   HOH B . 
Z 6 HOH   21 521 83  HOH   HOH B . 
Z 6 HOH   22 522 47  HOH   HOH B . 
Z 6 HOH   23 523 70  HOH   HOH B . 
Z 6 HOH   24 524 69  HOH   HOH B . 
Z 6 HOH   25 525 97  HOH   HOH B . 
Z 6 HOH   26 526 3   HOH   HOH B . 
Z 6 HOH   27 527 53  HOH   HOH B . 
Z 6 HOH   28 528 109 HOH   HOH B . 
Z 6 HOH   29 529 56  HOH   HOH B . 
Z 6 HOH   30 530 66  HOH   HOH B . 
Z 6 HOH   31 531 68  HOH   HOH B . 
Z 6 HOH   32 532 60  HOH   HOH B . 
Z 6 HOH   33 533 59  HOH   HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 3   ? CG  ? A ARG 6   CG  
2  1 Y 1 A ARG 3   ? CD  ? A ARG 6   CD  
3  1 Y 1 A ARG 3   ? NE  ? A ARG 6   NE  
4  1 Y 1 A ARG 3   ? CZ  ? A ARG 6   CZ  
5  1 Y 1 A ARG 3   ? NH1 ? A ARG 6   NH1 
6  1 Y 1 A ARG 3   ? NH2 ? A ARG 6   NH2 
7  1 Y 1 A THR 191 ? OG1 ? A THR 194 OG1 
8  1 Y 1 A THR 191 ? CG2 ? A THR 194 CG2 
9  1 Y 1 A CYS 192 ? SG  ? A CYS 195 SG  
10 1 Y 1 A LYS 228 ? CG  ? A LYS 231 CG  
11 1 Y 1 A LYS 228 ? CD  ? A LYS 231 CD  
12 1 Y 1 A LYS 228 ? CE  ? A LYS 231 CE  
13 1 Y 1 A LYS 228 ? NZ  ? A LYS 231 NZ  
14 1 Y 1 A LYS 315 ? CG  ? A LYS 318 CG  
15 1 Y 1 A LYS 315 ? CD  ? A LYS 318 CD  
16 1 Y 1 A LYS 315 ? CE  ? A LYS 318 CE  
17 1 Y 1 A LYS 315 ? NZ  ? A LYS 318 NZ  
18 1 Y 1 B ILE 5   ? CG1 ? B ILE 8   CG1 
19 1 Y 1 B ILE 5   ? CG2 ? B ILE 8   CG2 
20 1 Y 1 B ILE 5   ? CD1 ? B ILE 8   CD1 
21 1 Y 1 B ASN 48  ? CG  ? B ASN 51  CG  
22 1 Y 1 B ASN 48  ? OD1 ? B ASN 51  OD1 
23 1 Y 1 B ASN 48  ? ND2 ? B ASN 51  ND2 
24 1 Y 1 B LYS 53  ? CG  ? B LYS 56  CG  
25 1 Y 1 B LYS 53  ? CD  ? B LYS 56  CD  
26 1 Y 1 B LYS 53  ? CE  ? B LYS 56  CE  
27 1 Y 1 B LYS 53  ? NZ  ? B LYS 56  NZ  
28 1 Y 1 B LEU 185 ? CG  ? B LEU 188 CG  
29 1 Y 1 B LEU 185 ? CD1 ? B LEU 188 CD1 
30 1 Y 1 B LEU 185 ? CD2 ? B LEU 188 CD2 
31 1 Y 1 B GLN 215 ? CG  ? B GLN 218 CG  
32 1 Y 1 B GLN 215 ? CD  ? B GLN 218 CD  
33 1 Y 1 B GLN 215 ? OE1 ? B GLN 218 OE1 
34 1 Y 1 B GLN 215 ? NE2 ? B GLN 218 NE2 
35 1 Y 1 B LYS 217 ? CG  ? B LYS 220 CG  
36 1 Y 1 B LYS 217 ? CD  ? B LYS 220 CD  
37 1 Y 1 B LYS 217 ? CE  ? B LYS 220 CE  
38 1 Y 1 B LYS 217 ? NZ  ? B LYS 220 NZ  
39 1 Y 1 B THR 231 ? OG1 ? B THR 234 OG1 
40 1 Y 1 B THR 231 ? CG2 ? B THR 234 CG2 
41 1 Y 1 B LYS 232 ? CG  ? B LYS 235 CG  
42 1 Y 1 B LYS 232 ? CD  ? B LYS 235 CD  
43 1 Y 1 B LYS 232 ? CE  ? B LYS 235 CE  
44 1 Y 1 B LYS 232 ? NZ  ? B LYS 235 NZ  
45 1 Y 1 B TYR 233 ? CG  ? B TYR 236 CG  
46 1 Y 1 B TYR 233 ? CD1 ? B TYR 236 CD1 
47 1 Y 1 B TYR 233 ? CD2 ? B TYR 236 CD2 
48 1 Y 1 B TYR 233 ? CE1 ? B TYR 236 CE1 
49 1 Y 1 B TYR 233 ? CE2 ? B TYR 236 CE2 
50 1 Y 1 B TYR 233 ? CZ  ? B TYR 236 CZ  
51 1 Y 1 B TYR 233 ? OH  ? B TYR 236 OH  
52 1 Y 1 B LEU 234 ? CG  ? B LEU 237 CG  
53 1 Y 1 B LEU 234 ? CD1 ? B LEU 237 CD1 
54 1 Y 1 B LEU 234 ? CD2 ? B LEU 237 CD2 
55 1 Y 1 B LYS 297 ? CG  ? B LYS 300 CG  
56 1 Y 1 B LYS 297 ? CD  ? B LYS 300 CD  
57 1 Y 1 B LYS 297 ? CE  ? B LYS 300 CE  
58 1 Y 1 B LYS 297 ? NZ  ? B LYS 300 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9D2K 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     112.983 
_cell.length_a_esd                 ? 
_cell.length_b                     112.983 
_cell.length_b_esd                 ? 
_cell.length_c                     223.834 
_cell.length_c_esd                 ? 
_cell.volume                       2857276.440 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9D2K 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                92 
_symmetry.space_group_name_Hall            'P 4abw 2nw' 
_symmetry.space_group_name_H-M             'P 41 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9D2K 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             5.32 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          76.88 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.6 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '200 mM zinc acetate, 0.1 M Bis-Tris pH 5.5-6.6, 10% PEG 8000' 
_exptl_crystal_grow.pdbx_pH_range   5.5-6.6 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-05-22 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9795 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9795 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          67.14 
_reflns.entry_id                                       9D2K 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.7 
_reflns.d_resolution_low                               28.89 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     39798 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.325 
_reflns.pdbx_Rpim_I_all                                0.091 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.989 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.312 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.7 
_reflns_shell.d_res_low                                     2.796 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.7 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3778 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               9.7 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               3.380 
_reflns_shell.pdbx_Rpim_I_all                               1.023 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.472 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          95.47 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  3.214 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               77.55 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9D2K 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.70 
_refine.ls_d_res_low                             28.89 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     39771 
_refine.ls_number_reflns_R_free                  2066 
_refine.ls_number_reflns_R_work                  37705 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.02 
_refine.ls_percent_reflns_R_free                 5.19 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2104 
_refine.ls_R_factor_R_free                       0.2320 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2092 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.8925 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3429 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.70 
_refine_hist.d_res_low                        28.89 
_refine_hist.number_atoms_solvent             98 
_refine_hist.number_atoms_total               4930 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4709 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         123 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0024  ? 4956 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5055  ? 6744 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0394  ? 735  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0034  ? 889  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.5791 ? 1828 ? f_dihedral_angle_d ? ? 
# 
_refine_ls_restr_ncs.pdbx_ordinal        1 
_refine_ls_restr_ncs.pdbx_refine_id      'X-RAY DIFFRACTION' 
_refine_ls_restr_ncs.dom_id              d_2 
_refine_ls_restr_ncs.pdbx_ens_id         ens_1 
_refine_ls_restr_ncs.rms_dev_position    0.780986452332 
_refine_ls_restr_ncs.weight_position     ? 
_refine_ls_restr_ncs.rms_dev_B_iso       ? 
_refine_ls_restr_ncs.weight_B_iso        ? 
_refine_ls_restr_ncs.pdbx_type           'Torsion NCS' 
_refine_ls_restr_ncs.pdbx_asym_id        A 
_refine_ls_restr_ncs.pdbx_auth_asym_id   A 
_refine_ls_restr_ncs.pdbx_number         ? 
_refine_ls_restr_ncs.pdbx_rms            ? 
_refine_ls_restr_ncs.pdbx_weight         ? 
_refine_ls_restr_ncs.ncs_model_details   ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.70 2.76  . . 123 2404 95.50 . . . . 0.3384 . . . . . . . . . . . 0.3537 
'X-RAY DIFFRACTION' 2.76 2.83  . . 121 2396 95.23 . . . . 0.3254 . . . . . . . . . . . 0.3325 
'X-RAY DIFFRACTION' 2.83 2.91  . . 131 2437 96.04 . . . . 0.3132 . . . . . . . . . . . 0.3113 
'X-RAY DIFFRACTION' 2.91 2.99  . . 127 2402 95.80 . . . . 0.3238 . . . . . . . . . . . 0.3378 
'X-RAY DIFFRACTION' 2.99 3.09  . . 138 2448 96.89 . . . . 0.2959 . . . . . . . . . . . 0.3593 
'X-RAY DIFFRACTION' 3.09 3.20  . . 135 2486 98.13 . . . . 0.2655 . . . . . . . . . . . 0.2769 
'X-RAY DIFFRACTION' 3.20 3.33  . . 131 2498 98.21 . . . . 0.2419 . . . . . . . . . . . 0.2836 
'X-RAY DIFFRACTION' 3.33 3.48  . . 167 2461 98.57 . . . . 0.2416 . . . . . . . . . . . 0.2750 
'X-RAY DIFFRACTION' 3.48 3.66  . . 130 2544 98.93 . . . . 0.2174 . . . . . . . . . . . 0.2737 
'X-RAY DIFFRACTION' 3.66 3.89  . . 132 2541 99.22 . . . . 0.1932 . . . . . . . . . . . 0.2122 
'X-RAY DIFFRACTION' 3.89 4.19  . . 140 2543 99.22 . . . . 0.1814 . . . . . . . . . . . 0.1944 
'X-RAY DIFFRACTION' 4.19 4.61  . . 127 2571 99.52 . . . . 0.1698 . . . . . . . . . . . 0.1864 
'X-RAY DIFFRACTION' 4.61 5.27  . . 141 2592 99.64 . . . . 0.1686 . . . . . . . . . . . 0.1813 
'X-RAY DIFFRACTION' 5.28 6.63  . . 153 2636 99.57 . . . . 0.1980 . . . . . . . . . . . 0.2177 
'X-RAY DIFFRACTION' 6.63 28.89 . . 170 2746 99.45 . . . . 0.1820 . . . . . . . . . . . 0.2107 
# 
_struct_ncs_oper.id             1 
_struct_ncs_oper.code           given 
_struct_ncs_oper.matrix[1][1]   -0.999344651132 
_struct_ncs_oper.matrix[1][2]   -0.0304494511381 
_struct_ncs_oper.matrix[1][3]   -0.0195729195221 
_struct_ncs_oper.matrix[2][1]   -0.0347400032928 
_struct_ncs_oper.matrix[2][2]   0.958696801568 
_struct_ncs_oper.matrix[2][3]   0.282300504488 
_struct_ncs_oper.matrix[3][1]   0.0101685999255 
_struct_ncs_oper.matrix[3][2]   0.28279546246 
_struct_ncs_oper.matrix[3][3]   -0.959126334738 
_struct_ncs_oper.vector[1]      0.355911688097 
_struct_ncs_oper.vector[2]      8.82721150113 
_struct_ncs_oper.vector[3]      -62.1437027232 
_struct_ncs_oper.details        ? 
# 
loop_
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.id 
_struct_ncs_dom.details 
ens_1 d_1 
;(chain "A" and (resid 4 or (resid 5 and (name N or name CA or name C or name O or name CB )) or resid 6 through 47 or (resid 48 and (name N or name CA or name C or name O or name CB )) or resid 49 through 52 or (resid 53 and (name N or name CA or name C or name O or name CB )) or resid 54 through 84 or resid 86 through 173 or resid 175 through 184 or (resid 185 and (name N or name CA or name C or name O or name CB )) or resid 198 through 214 or (resid 215 and (name N or name CA or name C or name O or name CB )) or resid 216 or (resid 217 and (name N or name CA or name C or name O or name CB )) or resid 218 or (resid 231 through 234 and (name N or name CA or name C or name O or name CB )) or resid 235 through 296 or (resid 297 and (name N or name CA or name C or name O or name CB )) or resid 298 through 312))
;
ens_1 d_2 
;(chain "B" and (resid 4 through 84 or resid 86 through 173 or resid 175 through 312))
;
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
ens_1 d_1 1 A THR 7   . A MET 87  . A THR 4   A MET 84  ? ? 
ens_1 d_1 2 A ALA 89  . A PHE 176 . A ALA 86  A PHE 173 ? ? 
ens_1 d_1 3 A HIS 178 . A LEU 188 . A HIS 175 A LEU 185 ? ? 
ens_1 d_1 4 A THR 201 . A LYS 221 . A THR 198 A LYS 218 ? ? 
ens_1 d_1 5 A THR 234 . A THR 315 . A THR 231 A THR 312 ? ? 
ens_1 d_2 1 B THR 7   . B MET 87  . B THR 4   B MET 84  ? ? 
ens_1 d_2 2 B ALA 89  . B PHE 176 . B ALA 86  B PHE 173 ? ? 
ens_1 d_2 3 B HIS 178 . B THR 315 . B HIS 175 B THR 312 ? ? 
# 
_struct_ncs_ens.id        ens_1 
_struct_ncs_ens.details   ? 
# 
_struct_ncs_ens_gen.ens_id     ens_1 
_struct_ncs_ens_gen.dom_id_1   d_2 
_struct_ncs_ens_gen.dom_id_2   d_1 
_struct_ncs_ens_gen.oper_id    1 
# 
_struct.entry_id                     9D2K 
_struct.title                        'SARS-CoV-2 Papain-like Protease (PLpro) complex with covalent inhibitor Jun13567' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9D2K 
_struct_keywords.text            
'SARS CoV-2, Papain-like Protease (PLpro), Covalent inhibitor, Jun13567, VIRAL PROTEIN, HYDROLASE-INHIBITOR complex' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN,HYDROLASE/INHIBITOR' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 5 ? 
K N N 5 ? 
L N N 5 ? 
M N N 5 ? 
N N N 5 ? 
O N N 2 ? 
P N N 4 ? 
Q N N 4 ? 
R N N 4 ? 
S N N 4 ? 
T N N 4 ? 
U N N 5 ? 
V N N 5 ? 
W N N 5 ? 
X N N 5 ? 
Y N N 6 ? 
Z N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1AB_SARS2 
_struct_ref.pdbx_db_accession          P0DTD1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFL
GRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVG
ELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESP
FVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIK
;
_struct_ref.pdbx_align_begin           1564 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9D2K A 4 ? 318 ? P0DTD1 1564 ? 1878 ? 1 315 
2 1 9D2K B 4 ? 318 ? P0DTD1 1564 ? 1878 ? 1 315 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9D2K SER A 1 ? UNP P0DTD1 ? ? 'expression tag' -2 1 
1 9D2K ASN A 2 ? UNP P0DTD1 ? ? 'expression tag' -1 2 
1 9D2K ALA A 3 ? UNP P0DTD1 ? ? 'expression tag' 0  3 
2 9D2K SER B 1 ? UNP P0DTD1 ? ? 'expression tag' -2 4 
2 9D2K ASN B 2 ? UNP P0DTD1 ? ? 'expression tag' -1 5 
2 9D2K ALA B 3 ? UNP P0DTD1 ? ? 'expression tag' 0  6 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,E,F,G,H,I,J,K,L,M,N,Y 
2 1 B,O,P,Q,R,S,T,U,V,W,X,Z     
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 29  ? GLY A 35  ? THR A 26  GLY A 32  1 ? 7  
HELX_P HELX_P2  AA2 HIS A 50  ? GLU A 54  ? HIS A 47  GLU A 51  5 ? 5  
HELX_P HELX_P3  AA3 ASP A 64  ? HIS A 76  ? ASP A 61  HIS A 73  1 ? 13 
HELX_P HELX_P4  AA4 SER A 81  ? LYS A 94  ? SER A 78  LYS A 91  1 ? 14 
HELX_P HELX_P5  AA5 ASN A 113 ? GLN A 124 ? ASN A 110 GLN A 121 1 ? 12 
HELX_P HELX_P6  AA6 PRO A 132 ? ALA A 144 ? PRO A 129 ALA A 141 1 ? 13 
HELX_P HELX_P7  AA7 ALA A 147 ? CYS A 158 ? ALA A 144 CYS A 155 1 ? 12 
HELX_P HELX_P8  AA8 ASP A 167 ? HIS A 178 ? ASP A 164 HIS A 175 1 ? 12 
HELX_P HELX_P9  AA9 GLY A 204 ? VAL A 208 ? GLY A 201 VAL A 205 1 ? 5  
HELX_P HELX_P10 AB1 SER A 215 ? GLY A 222 ? SER A 212 GLY A 219 1 ? 8  
HELX_P HELX_P11 AB2 THR B 29  ? GLY B 35  ? THR B 26  GLY B 32  1 ? 7  
HELX_P HELX_P12 AB3 HIS B 50  ? GLU B 54  ? HIS B 47  GLU B 51  5 ? 5  
HELX_P HELX_P13 AB4 ASP B 64  ? HIS B 76  ? ASP B 61  HIS B 73  1 ? 13 
HELX_P HELX_P14 AB5 SER B 81  ? LYS B 94  ? SER B 78  LYS B 91  1 ? 14 
HELX_P HELX_P15 AB6 ASN B 113 ? GLN B 124 ? ASN B 110 GLN B 121 1 ? 12 
HELX_P HELX_P16 AB7 PRO B 132 ? ALA B 144 ? PRO B 129 ALA B 141 1 ? 13 
HELX_P HELX_P17 AB8 ALA B 147 ? CYS B 158 ? ALA B 144 CYS B 155 1 ? 12 
HELX_P HELX_P18 AB9 ASP B 167 ? HIS B 178 ? ASP B 164 HIS B 175 1 ? 12 
HELX_P HELX_P19 AC1 GLY B 204 ? VAL B 208 ? GLY B 201 VAL B 205 1 ? 5  
HELX_P HELX_P20 AC2 SER B 215 ? LYS B 221 ? SER B 212 LYS B 218 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale one ? A CYS 114 SG  ? ? ? 1_555 C A1A6J .  C37 ? ? A CYS 111 A A1A6J 401 1_555 ? ? ? ? ? ? ? 1.832 ? ? 
covale2  covale one ? B CYS 114 SG  ? ? ? 1_555 O A1A6J .  C37 ? ? B CYS 111 B A1A6J 401 1_555 ? ? ? ? ? ? ? 1.825 ? ? 
metalc1  metalc ?   ? A ASP 65  OD1 ? ? ? 1_555 P ZN    .  ZN  ? ? A ASP 62  B ZN    402 6_454 ? ? ? ? ? ? ? 1.912 ? ? 
metalc2  metalc ?   ? A HIS 76  ND1 ? ? ? 1_555 E ZN    .  ZN  ? ? A HIS 73  A ZN    403 1_555 ? ? ? ? ? ? ? 2.286 ? ? 
metalc3  metalc ?   ? A HIS 92  ND1 ? ? ? 1_555 F ZN    .  ZN  ? ? A HIS 89  A ZN    404 1_555 ? ? ? ? ? ? ? 2.275 ? ? 
metalc4  metalc ?   ? A CYS 192 SG  ? ? ? 1_555 I ZN    .  ZN  ? ? A CYS 189 A ZN    407 1_555 ? ? ? ? ? ? ? 2.308 ? ? 
metalc5  metalc ?   ? A CYS 227 SG  ? ? ? 1_555 I ZN    .  ZN  ? ? A CYS 224 A ZN    407 1_555 ? ? ? ? ? ? ? 2.320 ? ? 
metalc6  metalc ?   ? A CYS 229 SG  ? ? ? 1_555 I ZN    .  ZN  ? ? A CYS 226 A ZN    407 1_555 ? ? ? ? ? ? ? 2.295 ? ? 
metalc7  metalc ?   ? A HIS 258 ND1 ? ? ? 1_555 G ZN    .  ZN  ? ? A HIS 255 A ZN    405 1_555 ? ? ? ? ? ? ? 2.307 ? ? 
metalc8  metalc ?   ? A CYS 273 SG  ? ? ? 1_555 F ZN    .  ZN  ? ? A CYS 270 A ZN    404 8_554 ? ? ? ? ? ? ? 2.337 ? ? 
metalc9  metalc ?   ? A HIS 275 NE2 ? ? ? 1_555 H ZN    .  ZN  ? ? A HIS 272 A ZN    406 1_555 ? ? ? ? ? ? ? 2.315 ? ? 
metalc10 metalc ?   ? A ASP 289 OD1 ? ? ? 1_555 H ZN    .  ZN  ? ? A ASP 286 A ZN    406 1_555 ? ? ? ? ? ? ? 2.257 ? ? 
metalc11 metalc ?   ? E ZN  .   ZN  ? ? ? 6_554 B ASP   65 OD1 ? ? A ZN  403 B ASP   62  1_555 ? ? ? ? ? ? ? 1.952 ? ? 
metalc12 metalc ?   ? B HIS 76  ND1 ? ? ? 1_555 P ZN    .  ZN  ? ? B HIS 73  B ZN    402 1_555 ? ? ? ? ? ? ? 2.282 ? ? 
metalc13 metalc ?   ? B HIS 92  ND1 ? ? ? 1_555 Q ZN    .  ZN  ? ? B HIS 89  B ZN    403 1_555 ? ? ? ? ? ? ? 2.306 ? ? 
metalc14 metalc ?   ? B ASP 111 OD2 ? ? ? 1_555 Q ZN    .  ZN  ? ? B ASP 108 B ZN    403 1_555 ? ? ? ? ? ? ? 2.552 ? ? 
metalc15 metalc ?   ? B HIS 178 NE2 ? ? ? 1_555 S ZN    .  ZN  ? ? B HIS 175 B ZN    405 1_555 ? ? ? ? ? ? ? 2.315 ? ? 
metalc16 metalc ?   ? B HIS 258 ND1 ? ? ? 1_555 R ZN    .  ZN  ? ? B HIS 255 B ZN    404 1_555 ? ? ? ? ? ? ? 2.307 ? ? 
metalc17 metalc ?   ? B HIS 275 NE2 ? ? ? 1_555 T ZN    .  ZN  ? ? B HIS 272 B ZN    406 1_555 ? ? ? ? ? ? ? 2.298 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD1 ? A ASP 65  ? A ASP 62  ? 1_555 ZN ? P ZN . ? B ZN 402 ? 6_454 ND1 ? B HIS 76  ? B HIS 73  ? 1_555 118.9 ? 
2 ND1 ? A HIS 76  ? A HIS 73  ? 1_555 ZN ? E ZN . ? A ZN 403 ? 1_555 OD1 ? B ASP 65  ? B ASP 62  ? 1_555 100.3 ? 
3 ND1 ? A HIS 92  ? A HIS 89  ? 1_555 ZN ? F ZN . ? A ZN 404 ? 1_555 SG  ? A CYS 273 ? A CYS 270 ? 1_555 93.5  ? 
4 SG  ? A CYS 192 ? A CYS 189 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 SG  ? A CYS 227 ? A CYS 224 ? 1_555 93.8  ? 
5 SG  ? A CYS 192 ? A CYS 189 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 SG  ? A CYS 229 ? A CYS 226 ? 1_555 102.4 ? 
6 SG  ? A CYS 227 ? A CYS 224 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 SG  ? A CYS 229 ? A CYS 226 ? 1_555 110.6 ? 
7 NE2 ? A HIS 275 ? A HIS 272 ? 1_555 ZN ? H ZN . ? A ZN 406 ? 1_555 OD1 ? A ASP 289 ? A ASP 286 ? 1_555 84.5  ? 
8 ND1 ? B HIS 92  ? B HIS 89  ? 1_555 ZN ? Q ZN . ? B ZN 403 ? 1_555 OD2 ? B ASP 111 ? B ASP 108 ? 1_555 102.2 ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 A1A6J C . ? CYS A 114 ? A1A6J A 401 ? 1_555 CYS A 111 ? 1_555 C37 SG CYS 1 A1A6J None 'Covalent chemical modification' 
2 A1A6J O . ? CYS B 114 ? A1A6J B 401 ? 1_555 CYS B 111 ? 1_555 C37 SG CYS 1 A1A6J None 'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 7 ? 
AA6 ? 5 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
AA9 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 20  ? ASP A 25  ? HIS A 17  ASP A 22  
AA1 2 THR A 7   ? THR A 13  ? THR A 4   THR A 10  
AA1 3 THR A 57  ? VAL A 60  ? THR A 54  VAL A 57  
AA1 4 THR A 37  ? LEU A 39  ? THR A 34  LEU A 36  
AA1 5 ALA A 42  ? ASP A 43  ? ALA A 39  ASP A 40  
AA2 1 GLN A 100 ? VAL A 101 ? GLN A 97  VAL A 98  
AA2 2 LEU A 104 ? THR A 105 ? LEU A 101 THR A 102 
AA3 1 GLY A 196 ? LYS A 203 ? GLY A 193 LYS A 200 
AA3 2 LYS A 185 ? CYS A 192 ? LYS A 182 CYS A 189 
AA3 3 GLN A 232 ? GLU A 241 ? GLN A 229 GLU A 238 
AA3 4 VAL A 223 ? PRO A 226 ? VAL A 220 PRO A 223 
AA4 1 GLY A 196 ? LYS A 203 ? GLY A 193 LYS A 200 
AA4 2 LYS A 185 ? CYS A 192 ? LYS A 182 CYS A 189 
AA4 3 GLN A 232 ? GLU A 241 ? GLN A 229 GLU A 238 
AA4 4 SER A 312 ? THR A 314 ? SER A 309 THR A 311 
AA5 1 MET A 209 ? MET A 211 ? MET A 206 MET A 208 
AA5 2 PHE A 244 ? LEU A 256 ? PHE A 241 LEU A 253 
AA5 3 TYR A 299 ? LYS A 309 ? TYR A 296 LYS A 306 
AA5 4 CYS A 263 ? ASN A 270 ? CYS A 260 ASN A 267 
AA5 5 CYS A 273 ? SER A 281 ? CYS A 270 SER A 278 
AA5 6 LEU A 285 ? ASP A 289 ? LEU A 282 ASP A 286 
AA5 7 LEU A 292 ? SER A 296 ? LEU A 289 SER A 293 
AA6 1 HIS B 20  ? VAL B 24  ? HIS B 17  VAL B 21  
AA6 2 ILE B 8   ? THR B 13  ? ILE B 5   THR B 10  
AA6 3 THR B 57  ? VAL B 60  ? THR B 54  VAL B 57  
AA6 4 THR B 37  ? LEU B 39  ? THR B 34  LEU B 36  
AA6 5 ALA B 42  ? ASP B 43  ? ALA B 39  ASP B 40  
AA7 1 GLN B 100 ? VAL B 101 ? GLN B 97  VAL B 98  
AA7 2 LEU B 104 ? THR B 105 ? LEU B 101 THR B 102 
AA8 1 LEU B 202 ? LYS B 203 ? LEU B 199 LYS B 200 
AA8 2 LYS B 185 ? VAL B 187 ? LYS B 182 VAL B 184 
AA8 3 GLN B 239 ? GLU B 241 ? GLN B 236 GLU B 238 
AA8 4 TYR B 313 ? THR B 314 ? TYR B 310 THR B 311 
AA9 1 MET B 209 ? MET B 211 ? MET B 206 MET B 208 
AA9 2 PHE B 244 ? LEU B 256 ? PHE B 241 LEU B 253 
AA9 3 TYR B 299 ? LYS B 309 ? TYR B 296 LYS B 306 
AA9 4 CYS B 263 ? ASN B 270 ? CYS B 260 ASN B 267 
AA9 5 CYS B 273 ? SER B 281 ? CYS B 270 SER B 278 
AA9 6 LEU B 285 ? ASP B 289 ? LEU B 282 ASP B 286 
AA9 7 LEU B 292 ? SER B 296 ? LEU B 289 SER B 293 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O HIS A 20  ? O HIS A 17  N THR A 12  ? N THR A 9   
AA1 2 3 N PHE A 11  ? N PHE A 8   O PHE A 58  ? O PHE A 55  
AA1 3 4 O TYR A 59  ? O TYR A 56  N TYR A 38  ? N TYR A 35  
AA1 4 5 N LEU A 39  ? N LEU A 36  O ALA A 42  ? O ALA A 39  
AA2 1 2 N VAL A 101 ? N VAL A 98  O LEU A 104 ? O LEU A 101 
AA3 1 2 O LEU A 202 ? O LEU A 199 N ARG A 186 ? N ARG A 183 
AA3 2 3 N LYS A 185 ? N LYS A 182 O GLU A 241 ? O GLU A 238 
AA3 3 4 O ALA A 233 ? O ALA A 230 N ILE A 225 ? N ILE A 222 
AA4 1 2 O LEU A 202 ? O LEU A 199 N ARG A 186 ? N ARG A 183 
AA4 2 3 N LYS A 185 ? N LYS A 182 O GLU A 241 ? O GLU A 238 
AA4 3 4 N GLN A 240 ? N GLN A 237 O TYR A 313 ? O TYR A 310 
AA5 1 2 N TYR A 210 ? N TYR A 207 O SER A 248 ? O SER A 245 
AA5 2 3 N MET A 247 ? N MET A 244 O VAL A 306 ? O VAL A 303 
AA5 3 4 O PHE A 307 ? O PHE A 304 N CYS A 263 ? N CYS A 260 
AA5 4 5 N GLU A 266 ? N GLU A 263 O LYS A 277 ? O LYS A 274 
AA5 5 6 N HIS A 278 ? N HIS A 275 O ILE A 288 ? O ILE A 285 
AA5 6 7 N CYS A 287 ? N CYS A 284 O THR A 294 ? O THR A 291 
AA6 1 2 O GLN B 22  ? O GLN B 19  N VAL B 10  ? N VAL B 7   
AA6 2 3 N PHE B 11  ? N PHE B 8   O PHE B 58  ? O PHE B 55  
AA6 3 4 O TYR B 59  ? O TYR B 56  N TYR B 38  ? N TYR B 35  
AA6 4 5 N LEU B 39  ? N LEU B 36  O ALA B 42  ? O ALA B 39  
AA7 1 2 N VAL B 101 ? N VAL B 98  O LEU B 104 ? O LEU B 101 
AA8 1 2 O LEU B 202 ? O LEU B 199 N ARG B 186 ? N ARG B 183 
AA8 2 3 N LYS B 185 ? N LYS B 182 O GLU B 241 ? O GLU B 238 
AA8 3 4 N GLN B 240 ? N GLN B 237 O TYR B 313 ? O TYR B 310 
AA9 1 2 N TYR B 210 ? N TYR B 207 O SER B 248 ? O SER B 245 
AA9 2 3 N MET B 247 ? N MET B 244 O VAL B 306 ? O VAL B 303 
AA9 3 4 O PHE B 307 ? O PHE B 304 N CYS B 263 ? N CYS B 260 
AA9 4 5 N GLU B 266 ? N GLU B 263 O LYS B 277 ? O LYS B 274 
AA9 5 6 N HIS B 278 ? N HIS B 275 O ILE B 288 ? O ILE B 285 
AA9 6 7 N CYS B 287 ? N CYS B 284 O THR B 294 ? O THR B 291 
# 
_pdbx_entry_details.entry_id                   9D2K 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE A 14  ? ? -123.01 -57.63  
2  1 LYS A 43  ? ? -100.07 47.80   
3  1 ALA A 107 ? ? -171.03 146.50  
4  1 GLU A 143 ? ? -105.85 73.64   
5  1 LYS A 279 ? ? -106.05 -132.22 
6  1 ASN A 308 ? ? -141.96 -69.67  
7  1 ILE B 14  ? ? -124.16 -56.50  
8  1 LYS B 43  ? ? -100.74 46.60   
9  1 ALA B 107 ? ? -170.48 145.53  
10 1 GLU B 143 ? ? -106.96 75.42   
11 1 THR B 259 ? ? -90.04  -60.71  
12 1 LYS B 279 ? ? -104.98 -131.54 
13 1 ASN B 308 ? ? -140.78 -70.47  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 -y+1/2,x+1/2,z+1/4  
3 y+1/2,-x+1/2,z+3/4  
4 x+1/2,-y+1/2,-z+3/4 
5 -x+1/2,y+1/2,-z+1/4 
6 -x,-y,z+1/2         
7 y,x,-z              
8 -y,-x,-z+1/2        
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A SER -2  ? A SER 1   
2  1 Y 1 A ASN -1  ? A ASN 2   
3  1 Y 1 A ALA 0   ? A ALA 3   
4  1 Y 1 A GLU 1   ? A GLU 4   
5  1 Y 1 A VAL 2   ? A VAL 5   
6  1 Y 1 B SER -2  ? B SER 1   
7  1 Y 1 B ASN -1  ? B ASN 2   
8  1 Y 1 B ALA 0   ? B ALA 3   
9  1 Y 1 B GLU 1   ? B GLU 4   
10 1 Y 1 B VAL 2   ? B VAL 5   
11 1 Y 1 B ARG 3   ? B ARG 6   
12 1 Y 1 B ASN 186 ? B ASN 189 
13 1 Y 1 B VAL 187 ? B VAL 190 
14 1 Y 1 B VAL 188 ? B VAL 191 
15 1 Y 1 B CYS 189 ? B CYS 192 
16 1 Y 1 B LYS 190 ? B LYS 193 
17 1 Y 1 B THR 191 ? B THR 194 
18 1 Y 1 B CYS 192 ? B CYS 195 
19 1 Y 1 B GLY 193 ? B GLY 196 
20 1 Y 1 B GLN 194 ? B GLN 197 
21 1 Y 1 B GLN 195 ? B GLN 198 
22 1 Y 1 B GLN 196 ? B GLN 199 
23 1 Y 1 B THR 197 ? B THR 200 
24 1 Y 1 B GLY 219 ? B GLY 222 
25 1 Y 1 B VAL 220 ? B VAL 223 
26 1 Y 1 B GLN 221 ? B GLN 224 
27 1 Y 1 B ILE 222 ? B ILE 225 
28 1 Y 1 B PRO 223 ? B PRO 226 
29 1 Y 1 B CYS 224 ? B CYS 227 
30 1 Y 1 B THR 225 ? B THR 228 
31 1 Y 1 B CYS 226 ? B CYS 229 
32 1 Y 1 B GLY 227 ? B GLY 230 
33 1 Y 1 B LYS 228 ? B LYS 231 
34 1 Y 1 B GLN 229 ? B GLN 232 
35 1 Y 1 B ALA 230 ? B ALA 233 
36 1 Y 1 B THR 313 ? B THR 316 
37 1 Y 1 B ILE 314 ? B ILE 317 
38 1 Y 1 B LYS 315 ? B LYS 318 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1A6J C13  C  N N 1   
A1A6J C14  C  Y N 2   
A1A6J C15  C  Y N 3   
A1A6J C16  C  Y N 4   
A1A6J C19  C  Y N 5   
A1A6J C20  C  Y N 6   
A1A6J N18  N  Y N 7   
A1A6J C12  C  Y N 8   
A1A6J C2   C  N N 9   
A1A6J C21  C  N N 10  
A1A6J C22  C  N N 11  
A1A6J C23  C  Y N 12  
A1A6J C24  C  N N 13  
A1A6J C25  C  Y N 14  
A1A6J C26  C  Y N 15  
A1A6J C27  C  Y N 16  
A1A6J C28  C  Y N 17  
A1A6J C29  C  Y N 18  
A1A6J C30  C  Y N 19  
A1A6J C31  C  N N 20  
A1A6J C32  C  N N 21  
A1A6J C33  C  N N 22  
A1A6J C36  C  N N 23  
A1A6J C37  C  N N 24  
A1A6J C38  C  N N 25  
A1A6J C39  C  N N 26  
A1A6J C4   C  N R 27  
A1A6J C41  C  N N 28  
A1A6J C42  C  N N 29  
A1A6J C43  C  N N 30  
A1A6J C44  C  N N 31  
A1A6J C45  C  N N 32  
A1A6J C5   C  Y N 33  
A1A6J C6   C  Y N 34  
A1A6J C7   C  Y N 35  
A1A6J C8   C  Y N 36  
A1A6J C9   C  Y N 37  
A1A6J N10  N  Y N 38  
A1A6J N11  N  Y N 39  
A1A6J N17  N  Y N 40  
A1A6J N3   N  N N 41  
A1A6J N34  N  N N 42  
A1A6J N35  N  N N 43  
A1A6J N40  N  N N 44  
A1A6J O1   O  N N 45  
A1A6J O46  O  N N 46  
A1A6J O47  O  N N 47  
A1A6J O48  O  N N 48  
A1A6J H1   H  N N 49  
A1A6J H2   H  N N 50  
A1A6J H3   H  N N 51  
A1A6J H4   H  N N 52  
A1A6J H5   H  N N 53  
A1A6J H6   H  N N 54  
A1A6J H7   H  N N 55  
A1A6J H8   H  N N 56  
A1A6J H9   H  N N 57  
A1A6J H10  H  N N 58  
A1A6J H11  H  N N 59  
A1A6J H12  H  N N 60  
A1A6J H13  H  N N 61  
A1A6J H14  H  N N 62  
A1A6J H15  H  N N 63  
A1A6J H16  H  N N 64  
A1A6J H17  H  N N 65  
A1A6J H18  H  N N 66  
A1A6J H19  H  N N 67  
A1A6J H20  H  N N 68  
A1A6J H21  H  N N 69  
A1A6J H22  H  N N 70  
A1A6J H23  H  N N 71  
A1A6J H24  H  N N 72  
A1A6J H25  H  N N 73  
A1A6J H26  H  N N 74  
A1A6J H27  H  N N 75  
A1A6J H28  H  N N 76  
A1A6J H29  H  N N 77  
A1A6J H30  H  N N 78  
A1A6J H31  H  N N 79  
A1A6J H32  H  N N 80  
A1A6J H33  H  N N 81  
A1A6J H34  H  N N 82  
A1A6J H35  H  N N 83  
A1A6J H36  H  N N 84  
A1A6J H37  H  N N 85  
A1A6J H38  H  N N 86  
A1A6J H39  H  N N 87  
A1A6J H40  H  N N 88  
A1A6J H41  H  N N 89  
A1A6J H42  H  N N 90  
A1A6J H43  H  N N 91  
A1A6J H44  H  N N 92  
ALA   N    N  N N 93  
ALA   CA   C  N S 94  
ALA   C    C  N N 95  
ALA   O    O  N N 96  
ALA   CB   C  N N 97  
ALA   OXT  O  N N 98  
ALA   H    H  N N 99  
ALA   H2   H  N N 100 
ALA   HA   H  N N 101 
ALA   HB1  H  N N 102 
ALA   HB2  H  N N 103 
ALA   HB3  H  N N 104 
ALA   HXT  H  N N 105 
ARG   N    N  N N 106 
ARG   CA   C  N S 107 
ARG   C    C  N N 108 
ARG   O    O  N N 109 
ARG   CB   C  N N 110 
ARG   CG   C  N N 111 
ARG   CD   C  N N 112 
ARG   NE   N  N N 113 
ARG   CZ   C  N N 114 
ARG   NH1  N  N N 115 
ARG   NH2  N  N N 116 
ARG   OXT  O  N N 117 
ARG   H    H  N N 118 
ARG   H2   H  N N 119 
ARG   HA   H  N N 120 
ARG   HB2  H  N N 121 
ARG   HB3  H  N N 122 
ARG   HG2  H  N N 123 
ARG   HG3  H  N N 124 
ARG   HD2  H  N N 125 
ARG   HD3  H  N N 126 
ARG   HE   H  N N 127 
ARG   HH11 H  N N 128 
ARG   HH12 H  N N 129 
ARG   HH21 H  N N 130 
ARG   HH22 H  N N 131 
ARG   HXT  H  N N 132 
ASN   N    N  N N 133 
ASN   CA   C  N S 134 
ASN   C    C  N N 135 
ASN   O    O  N N 136 
ASN   CB   C  N N 137 
ASN   CG   C  N N 138 
ASN   OD1  O  N N 139 
ASN   ND2  N  N N 140 
ASN   OXT  O  N N 141 
ASN   H    H  N N 142 
ASN   H2   H  N N 143 
ASN   HA   H  N N 144 
ASN   HB2  H  N N 145 
ASN   HB3  H  N N 146 
ASN   HD21 H  N N 147 
ASN   HD22 H  N N 148 
ASN   HXT  H  N N 149 
ASP   N    N  N N 150 
ASP   CA   C  N S 151 
ASP   C    C  N N 152 
ASP   O    O  N N 153 
ASP   CB   C  N N 154 
ASP   CG   C  N N 155 
ASP   OD1  O  N N 156 
ASP   OD2  O  N N 157 
ASP   OXT  O  N N 158 
ASP   H    H  N N 159 
ASP   H2   H  N N 160 
ASP   HA   H  N N 161 
ASP   HB2  H  N N 162 
ASP   HB3  H  N N 163 
ASP   HD2  H  N N 164 
ASP   HXT  H  N N 165 
CL    CL   CL N N 166 
CYS   N    N  N N 167 
CYS   CA   C  N R 168 
CYS   C    C  N N 169 
CYS   O    O  N N 170 
CYS   CB   C  N N 171 
CYS   SG   S  N N 172 
CYS   OXT  O  N N 173 
CYS   H    H  N N 174 
CYS   H2   H  N N 175 
CYS   HA   H  N N 176 
CYS   HB2  H  N N 177 
CYS   HB3  H  N N 178 
CYS   HG   H  N N 179 
CYS   HXT  H  N N 180 
DTT   S1   S  N N 181 
DTT   C1   C  N N 182 
DTT   C2   C  N R 183 
DTT   O2   O  N N 184 
DTT   C3   C  N R 185 
DTT   O3   O  N N 186 
DTT   C4   C  N N 187 
DTT   S4   S  N N 188 
DTT   HS1  H  N N 189 
DTT   H11  H  N N 190 
DTT   H12  H  N N 191 
DTT   H2   H  N N 192 
DTT   HO2  H  N N 193 
DTT   H3   H  N N 194 
DTT   HO3  H  N N 195 
DTT   H41  H  N N 196 
DTT   H42  H  N N 197 
DTT   HS2  H  N N 198 
GLN   N    N  N N 199 
GLN   CA   C  N S 200 
GLN   C    C  N N 201 
GLN   O    O  N N 202 
GLN   CB   C  N N 203 
GLN   CG   C  N N 204 
GLN   CD   C  N N 205 
GLN   OE1  O  N N 206 
GLN   NE2  N  N N 207 
GLN   OXT  O  N N 208 
GLN   H    H  N N 209 
GLN   H2   H  N N 210 
GLN   HA   H  N N 211 
GLN   HB2  H  N N 212 
GLN   HB3  H  N N 213 
GLN   HG2  H  N N 214 
GLN   HG3  H  N N 215 
GLN   HE21 H  N N 216 
GLN   HE22 H  N N 217 
GLN   HXT  H  N N 218 
GLU   N    N  N N 219 
GLU   CA   C  N S 220 
GLU   C    C  N N 221 
GLU   O    O  N N 222 
GLU   CB   C  N N 223 
GLU   CG   C  N N 224 
GLU   CD   C  N N 225 
GLU   OE1  O  N N 226 
GLU   OE2  O  N N 227 
GLU   OXT  O  N N 228 
GLU   H    H  N N 229 
GLU   H2   H  N N 230 
GLU   HA   H  N N 231 
GLU   HB2  H  N N 232 
GLU   HB3  H  N N 233 
GLU   HG2  H  N N 234 
GLU   HG3  H  N N 235 
GLU   HE2  H  N N 236 
GLU   HXT  H  N N 237 
GLY   N    N  N N 238 
GLY   CA   C  N N 239 
GLY   C    C  N N 240 
GLY   O    O  N N 241 
GLY   OXT  O  N N 242 
GLY   H    H  N N 243 
GLY   H2   H  N N 244 
GLY   HA2  H  N N 245 
GLY   HA3  H  N N 246 
GLY   HXT  H  N N 247 
HIS   N    N  N N 248 
HIS   CA   C  N S 249 
HIS   C    C  N N 250 
HIS   O    O  N N 251 
HIS   CB   C  N N 252 
HIS   CG   C  Y N 253 
HIS   ND1  N  Y N 254 
HIS   CD2  C  Y N 255 
HIS   CE1  C  Y N 256 
HIS   NE2  N  Y N 257 
HIS   OXT  O  N N 258 
HIS   H    H  N N 259 
HIS   H2   H  N N 260 
HIS   HA   H  N N 261 
HIS   HB2  H  N N 262 
HIS   HB3  H  N N 263 
HIS   HD1  H  N N 264 
HIS   HD2  H  N N 265 
HIS   HE1  H  N N 266 
HIS   HE2  H  N N 267 
HIS   HXT  H  N N 268 
HOH   O    O  N N 269 
HOH   H1   H  N N 270 
HOH   H2   H  N N 271 
ILE   N    N  N N 272 
ILE   CA   C  N S 273 
ILE   C    C  N N 274 
ILE   O    O  N N 275 
ILE   CB   C  N S 276 
ILE   CG1  C  N N 277 
ILE   CG2  C  N N 278 
ILE   CD1  C  N N 279 
ILE   OXT  O  N N 280 
ILE   H    H  N N 281 
ILE   H2   H  N N 282 
ILE   HA   H  N N 283 
ILE   HB   H  N N 284 
ILE   HG12 H  N N 285 
ILE   HG13 H  N N 286 
ILE   HG21 H  N N 287 
ILE   HG22 H  N N 288 
ILE   HG23 H  N N 289 
ILE   HD11 H  N N 290 
ILE   HD12 H  N N 291 
ILE   HD13 H  N N 292 
ILE   HXT  H  N N 293 
LEU   N    N  N N 294 
LEU   CA   C  N S 295 
LEU   C    C  N N 296 
LEU   O    O  N N 297 
LEU   CB   C  N N 298 
LEU   CG   C  N N 299 
LEU   CD1  C  N N 300 
LEU   CD2  C  N N 301 
LEU   OXT  O  N N 302 
LEU   H    H  N N 303 
LEU   H2   H  N N 304 
LEU   HA   H  N N 305 
LEU   HB2  H  N N 306 
LEU   HB3  H  N N 307 
LEU   HG   H  N N 308 
LEU   HD11 H  N N 309 
LEU   HD12 H  N N 310 
LEU   HD13 H  N N 311 
LEU   HD21 H  N N 312 
LEU   HD22 H  N N 313 
LEU   HD23 H  N N 314 
LEU   HXT  H  N N 315 
LYS   N    N  N N 316 
LYS   CA   C  N S 317 
LYS   C    C  N N 318 
LYS   O    O  N N 319 
LYS   CB   C  N N 320 
LYS   CG   C  N N 321 
LYS   CD   C  N N 322 
LYS   CE   C  N N 323 
LYS   NZ   N  N N 324 
LYS   OXT  O  N N 325 
LYS   H    H  N N 326 
LYS   H2   H  N N 327 
LYS   HA   H  N N 328 
LYS   HB2  H  N N 329 
LYS   HB3  H  N N 330 
LYS   HG2  H  N N 331 
LYS   HG3  H  N N 332 
LYS   HD2  H  N N 333 
LYS   HD3  H  N N 334 
LYS   HE2  H  N N 335 
LYS   HE3  H  N N 336 
LYS   HZ1  H  N N 337 
LYS   HZ2  H  N N 338 
LYS   HZ3  H  N N 339 
LYS   HXT  H  N N 340 
MET   N    N  N N 341 
MET   CA   C  N S 342 
MET   C    C  N N 343 
MET   O    O  N N 344 
MET   CB   C  N N 345 
MET   CG   C  N N 346 
MET   SD   S  N N 347 
MET   CE   C  N N 348 
MET   OXT  O  N N 349 
MET   H    H  N N 350 
MET   H2   H  N N 351 
MET   HA   H  N N 352 
MET   HB2  H  N N 353 
MET   HB3  H  N N 354 
MET   HG2  H  N N 355 
MET   HG3  H  N N 356 
MET   HE1  H  N N 357 
MET   HE2  H  N N 358 
MET   HE3  H  N N 359 
MET   HXT  H  N N 360 
PHE   N    N  N N 361 
PHE   CA   C  N S 362 
PHE   C    C  N N 363 
PHE   O    O  N N 364 
PHE   CB   C  N N 365 
PHE   CG   C  Y N 366 
PHE   CD1  C  Y N 367 
PHE   CD2  C  Y N 368 
PHE   CE1  C  Y N 369 
PHE   CE2  C  Y N 370 
PHE   CZ   C  Y N 371 
PHE   OXT  O  N N 372 
PHE   H    H  N N 373 
PHE   H2   H  N N 374 
PHE   HA   H  N N 375 
PHE   HB2  H  N N 376 
PHE   HB3  H  N N 377 
PHE   HD1  H  N N 378 
PHE   HD2  H  N N 379 
PHE   HE1  H  N N 380 
PHE   HE2  H  N N 381 
PHE   HZ   H  N N 382 
PHE   HXT  H  N N 383 
PRO   N    N  N N 384 
PRO   CA   C  N S 385 
PRO   C    C  N N 386 
PRO   O    O  N N 387 
PRO   CB   C  N N 388 
PRO   CG   C  N N 389 
PRO   CD   C  N N 390 
PRO   OXT  O  N N 391 
PRO   H    H  N N 392 
PRO   HA   H  N N 393 
PRO   HB2  H  N N 394 
PRO   HB3  H  N N 395 
PRO   HG2  H  N N 396 
PRO   HG3  H  N N 397 
PRO   HD2  H  N N 398 
PRO   HD3  H  N N 399 
PRO   HXT  H  N N 400 
SER   N    N  N N 401 
SER   CA   C  N S 402 
SER   C    C  N N 403 
SER   O    O  N N 404 
SER   CB   C  N N 405 
SER   OG   O  N N 406 
SER   OXT  O  N N 407 
SER   H    H  N N 408 
SER   H2   H  N N 409 
SER   HA   H  N N 410 
SER   HB2  H  N N 411 
SER   HB3  H  N N 412 
SER   HG   H  N N 413 
SER   HXT  H  N N 414 
THR   N    N  N N 415 
THR   CA   C  N S 416 
THR   C    C  N N 417 
THR   O    O  N N 418 
THR   CB   C  N R 419 
THR   OG1  O  N N 420 
THR   CG2  C  N N 421 
THR   OXT  O  N N 422 
THR   H    H  N N 423 
THR   H2   H  N N 424 
THR   HA   H  N N 425 
THR   HB   H  N N 426 
THR   HG1  H  N N 427 
THR   HG21 H  N N 428 
THR   HG22 H  N N 429 
THR   HG23 H  N N 430 
THR   HXT  H  N N 431 
TRP   N    N  N N 432 
TRP   CA   C  N S 433 
TRP   C    C  N N 434 
TRP   O    O  N N 435 
TRP   CB   C  N N 436 
TRP   CG   C  Y N 437 
TRP   CD1  C  Y N 438 
TRP   CD2  C  Y N 439 
TRP   NE1  N  Y N 440 
TRP   CE2  C  Y N 441 
TRP   CE3  C  Y N 442 
TRP   CZ2  C  Y N 443 
TRP   CZ3  C  Y N 444 
TRP   CH2  C  Y N 445 
TRP   OXT  O  N N 446 
TRP   H    H  N N 447 
TRP   H2   H  N N 448 
TRP   HA   H  N N 449 
TRP   HB2  H  N N 450 
TRP   HB3  H  N N 451 
TRP   HD1  H  N N 452 
TRP   HE1  H  N N 453 
TRP   HE3  H  N N 454 
TRP   HZ2  H  N N 455 
TRP   HZ3  H  N N 456 
TRP   HH2  H  N N 457 
TRP   HXT  H  N N 458 
TYR   N    N  N N 459 
TYR   CA   C  N S 460 
TYR   C    C  N N 461 
TYR   O    O  N N 462 
TYR   CB   C  N N 463 
TYR   CG   C  Y N 464 
TYR   CD1  C  Y N 465 
TYR   CD2  C  Y N 466 
TYR   CE1  C  Y N 467 
TYR   CE2  C  Y N 468 
TYR   CZ   C  Y N 469 
TYR   OH   O  N N 470 
TYR   OXT  O  N N 471 
TYR   H    H  N N 472 
TYR   H2   H  N N 473 
TYR   HA   H  N N 474 
TYR   HB2  H  N N 475 
TYR   HB3  H  N N 476 
TYR   HD1  H  N N 477 
TYR   HD2  H  N N 478 
TYR   HE1  H  N N 479 
TYR   HE2  H  N N 480 
TYR   HH   H  N N 481 
TYR   HXT  H  N N 482 
VAL   N    N  N N 483 
VAL   CA   C  N S 484 
VAL   C    C  N N 485 
VAL   O    O  N N 486 
VAL   CB   C  N N 487 
VAL   CG1  C  N N 488 
VAL   CG2  C  N N 489 
VAL   OXT  O  N N 490 
VAL   H    H  N N 491 
VAL   H2   H  N N 492 
VAL   HA   H  N N 493 
VAL   HB   H  N N 494 
VAL   HG11 H  N N 495 
VAL   HG12 H  N N 496 
VAL   HG13 H  N N 497 
VAL   HG21 H  N N 498 
VAL   HG22 H  N N 499 
VAL   HG23 H  N N 500 
VAL   HXT  H  N N 501 
ZN    ZN   ZN N N 502 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1A6J C13 N10  sing N N 1   
A1A6J N10 N11  sing Y N 2   
A1A6J N10 C9   sing Y N 3   
A1A6J N11 C12  doub Y N 4   
A1A6J C9  C8   doub Y N 5   
A1A6J C12 C8   sing Y N 6   
A1A6J C8  C7   sing N N 7   
A1A6J C7  C14  doub Y N 8   
A1A6J C7  C6   sing Y N 9   
A1A6J C14 C15  sing Y N 10  
A1A6J C21 N18  sing N N 11  
A1A6J C21 C22  sing N N 12  
A1A6J N17 N18  sing Y N 13  
A1A6J N17 C16  doub Y N 14  
A1A6J O1  C2   doub N N 15  
A1A6J C6  C5   doub Y N 16  
A1A6J O48 C33  doub N N 17  
A1A6J N18 C19  sing Y N 18  
A1A6J C15 C16  sing N N 19  
A1A6J C15 C23  doub Y N 20  
A1A6J C43 C42  sing N N 21  
A1A6J C45 C42  sing N N 22  
A1A6J C16 C20  sing Y N 23  
A1A6J C41 C42  sing N N 24  
A1A6J C41 N40  sing N N 25  
A1A6J C32 C33  sing N N 26  
A1A6J C32 C31  sing N N 27  
A1A6J C2  C25  sing N N 28  
A1A6J C2  N3   sing N N 29  
A1A6J C30 C25  doub Y N 30  
A1A6J C30 C29  sing Y N 31  
A1A6J C5  C23  sing Y N 32  
A1A6J C5  C4   sing N N 33  
A1A6J C25 C26  sing Y N 34  
A1A6J C29 C28  doub Y N 35  
A1A6J C42 C44  sing N N 36  
A1A6J C33 N34  sing N N 37  
A1A6J C26 C27  doub Y N 38  
A1A6J C26 C31  sing N N 39  
A1A6J C28 C27  sing Y N 40  
A1A6J C19 C20  doub Y N 41  
A1A6J C4  N3   sing N N 42  
A1A6J C4  C24  sing N N 43  
A1A6J N40 C44  sing N N 44  
A1A6J N40 C39  sing N N 45  
A1A6J N34 N35  sing N N 46  
A1A6J C38 C39  sing N N 47  
A1A6J C38 C37  sing N N 48  
A1A6J N35 C36  sing N N 49  
A1A6J C39 O46  doub N N 50  
A1A6J C36 O47  doub N N 51  
A1A6J C36 C37  sing N N 52  
A1A6J C13 H1   sing N N 53  
A1A6J C13 H2   sing N N 54  
A1A6J C13 H3   sing N N 55  
A1A6J C14 H4   sing N N 56  
A1A6J C19 H5   sing N N 57  
A1A6J C20 H6   sing N N 58  
A1A6J C12 H7   sing N N 59  
A1A6J C21 H8   sing N N 60  
A1A6J C21 H9   sing N N 61  
A1A6J C22 H10  sing N N 62  
A1A6J C22 H11  sing N N 63  
A1A6J C22 H12  sing N N 64  
A1A6J C23 H13  sing N N 65  
A1A6J C24 H14  sing N N 66  
A1A6J C24 H15  sing N N 67  
A1A6J C24 H16  sing N N 68  
A1A6J C27 H17  sing N N 69  
A1A6J C28 H18  sing N N 70  
A1A6J C29 H19  sing N N 71  
A1A6J C30 H20  sing N N 72  
A1A6J C31 H21  sing N N 73  
A1A6J C31 H22  sing N N 74  
A1A6J C32 H23  sing N N 75  
A1A6J C32 H24  sing N N 76  
A1A6J C37 H25  sing N N 77  
A1A6J C37 H26  sing N N 78  
A1A6J C38 H27  sing N N 79  
A1A6J C38 H28  sing N N 80  
A1A6J C4  H29  sing N N 81  
A1A6J C41 H30  sing N N 82  
A1A6J C41 H31  sing N N 83  
A1A6J C43 H32  sing N N 84  
A1A6J C43 H33  sing N N 85  
A1A6J C43 H34  sing N N 86  
A1A6J C44 H35  sing N N 87  
A1A6J C44 H36  sing N N 88  
A1A6J C45 H37  sing N N 89  
A1A6J C45 H38  sing N N 90  
A1A6J C45 H39  sing N N 91  
A1A6J C6  H40  sing N N 92  
A1A6J C9  H41  sing N N 93  
A1A6J N3  H42  sing N N 94  
A1A6J N34 H43  sing N N 95  
A1A6J N35 H44  sing N N 96  
ALA   N   CA   sing N N 97  
ALA   N   H    sing N N 98  
ALA   N   H2   sing N N 99  
ALA   CA  C    sing N N 100 
ALA   CA  CB   sing N N 101 
ALA   CA  HA   sing N N 102 
ALA   C   O    doub N N 103 
ALA   C   OXT  sing N N 104 
ALA   CB  HB1  sing N N 105 
ALA   CB  HB2  sing N N 106 
ALA   CB  HB3  sing N N 107 
ALA   OXT HXT  sing N N 108 
ARG   N   CA   sing N N 109 
ARG   N   H    sing N N 110 
ARG   N   H2   sing N N 111 
ARG   CA  C    sing N N 112 
ARG   CA  CB   sing N N 113 
ARG   CA  HA   sing N N 114 
ARG   C   O    doub N N 115 
ARG   C   OXT  sing N N 116 
ARG   CB  CG   sing N N 117 
ARG   CB  HB2  sing N N 118 
ARG   CB  HB3  sing N N 119 
ARG   CG  CD   sing N N 120 
ARG   CG  HG2  sing N N 121 
ARG   CG  HG3  sing N N 122 
ARG   CD  NE   sing N N 123 
ARG   CD  HD2  sing N N 124 
ARG   CD  HD3  sing N N 125 
ARG   NE  CZ   sing N N 126 
ARG   NE  HE   sing N N 127 
ARG   CZ  NH1  sing N N 128 
ARG   CZ  NH2  doub N N 129 
ARG   NH1 HH11 sing N N 130 
ARG   NH1 HH12 sing N N 131 
ARG   NH2 HH21 sing N N 132 
ARG   NH2 HH22 sing N N 133 
ARG   OXT HXT  sing N N 134 
ASN   N   CA   sing N N 135 
ASN   N   H    sing N N 136 
ASN   N   H2   sing N N 137 
ASN   CA  C    sing N N 138 
ASN   CA  CB   sing N N 139 
ASN   CA  HA   sing N N 140 
ASN   C   O    doub N N 141 
ASN   C   OXT  sing N N 142 
ASN   CB  CG   sing N N 143 
ASN   CB  HB2  sing N N 144 
ASN   CB  HB3  sing N N 145 
ASN   CG  OD1  doub N N 146 
ASN   CG  ND2  sing N N 147 
ASN   ND2 HD21 sing N N 148 
ASN   ND2 HD22 sing N N 149 
ASN   OXT HXT  sing N N 150 
ASP   N   CA   sing N N 151 
ASP   N   H    sing N N 152 
ASP   N   H2   sing N N 153 
ASP   CA  C    sing N N 154 
ASP   CA  CB   sing N N 155 
ASP   CA  HA   sing N N 156 
ASP   C   O    doub N N 157 
ASP   C   OXT  sing N N 158 
ASP   CB  CG   sing N N 159 
ASP   CB  HB2  sing N N 160 
ASP   CB  HB3  sing N N 161 
ASP   CG  OD1  doub N N 162 
ASP   CG  OD2  sing N N 163 
ASP   OD2 HD2  sing N N 164 
ASP   OXT HXT  sing N N 165 
CYS   N   CA   sing N N 166 
CYS   N   H    sing N N 167 
CYS   N   H2   sing N N 168 
CYS   CA  C    sing N N 169 
CYS   CA  CB   sing N N 170 
CYS   CA  HA   sing N N 171 
CYS   C   O    doub N N 172 
CYS   C   OXT  sing N N 173 
CYS   CB  SG   sing N N 174 
CYS   CB  HB2  sing N N 175 
CYS   CB  HB3  sing N N 176 
CYS   SG  HG   sing N N 177 
CYS   OXT HXT  sing N N 178 
DTT   S1  C1   sing N N 179 
DTT   S1  HS1  sing N N 180 
DTT   C1  C2   sing N N 181 
DTT   C1  H11  sing N N 182 
DTT   C1  H12  sing N N 183 
DTT   C2  O2   sing N N 184 
DTT   C2  C3   sing N N 185 
DTT   C2  H2   sing N N 186 
DTT   O2  HO2  sing N N 187 
DTT   C3  O3   sing N N 188 
DTT   C3  C4   sing N N 189 
DTT   C3  H3   sing N N 190 
DTT   O3  HO3  sing N N 191 
DTT   C4  S4   sing N N 192 
DTT   C4  H41  sing N N 193 
DTT   C4  H42  sing N N 194 
DTT   S4  HS2  sing N N 195 
GLN   N   CA   sing N N 196 
GLN   N   H    sing N N 197 
GLN   N   H2   sing N N 198 
GLN   CA  C    sing N N 199 
GLN   CA  CB   sing N N 200 
GLN   CA  HA   sing N N 201 
GLN   C   O    doub N N 202 
GLN   C   OXT  sing N N 203 
GLN   CB  CG   sing N N 204 
GLN   CB  HB2  sing N N 205 
GLN   CB  HB3  sing N N 206 
GLN   CG  CD   sing N N 207 
GLN   CG  HG2  sing N N 208 
GLN   CG  HG3  sing N N 209 
GLN   CD  OE1  doub N N 210 
GLN   CD  NE2  sing N N 211 
GLN   NE2 HE21 sing N N 212 
GLN   NE2 HE22 sing N N 213 
GLN   OXT HXT  sing N N 214 
GLU   N   CA   sing N N 215 
GLU   N   H    sing N N 216 
GLU   N   H2   sing N N 217 
GLU   CA  C    sing N N 218 
GLU   CA  CB   sing N N 219 
GLU   CA  HA   sing N N 220 
GLU   C   O    doub N N 221 
GLU   C   OXT  sing N N 222 
GLU   CB  CG   sing N N 223 
GLU   CB  HB2  sing N N 224 
GLU   CB  HB3  sing N N 225 
GLU   CG  CD   sing N N 226 
GLU   CG  HG2  sing N N 227 
GLU   CG  HG3  sing N N 228 
GLU   CD  OE1  doub N N 229 
GLU   CD  OE2  sing N N 230 
GLU   OE2 HE2  sing N N 231 
GLU   OXT HXT  sing N N 232 
GLY   N   CA   sing N N 233 
GLY   N   H    sing N N 234 
GLY   N   H2   sing N N 235 
GLY   CA  C    sing N N 236 
GLY   CA  HA2  sing N N 237 
GLY   CA  HA3  sing N N 238 
GLY   C   O    doub N N 239 
GLY   C   OXT  sing N N 240 
GLY   OXT HXT  sing N N 241 
HIS   N   CA   sing N N 242 
HIS   N   H    sing N N 243 
HIS   N   H2   sing N N 244 
HIS   CA  C    sing N N 245 
HIS   CA  CB   sing N N 246 
HIS   CA  HA   sing N N 247 
HIS   C   O    doub N N 248 
HIS   C   OXT  sing N N 249 
HIS   CB  CG   sing N N 250 
HIS   CB  HB2  sing N N 251 
HIS   CB  HB3  sing N N 252 
HIS   CG  ND1  sing Y N 253 
HIS   CG  CD2  doub Y N 254 
HIS   ND1 CE1  doub Y N 255 
HIS   ND1 HD1  sing N N 256 
HIS   CD2 NE2  sing Y N 257 
HIS   CD2 HD2  sing N N 258 
HIS   CE1 NE2  sing Y N 259 
HIS   CE1 HE1  sing N N 260 
HIS   NE2 HE2  sing N N 261 
HIS   OXT HXT  sing N N 262 
HOH   O   H1   sing N N 263 
HOH   O   H2   sing N N 264 
ILE   N   CA   sing N N 265 
ILE   N   H    sing N N 266 
ILE   N   H2   sing N N 267 
ILE   CA  C    sing N N 268 
ILE   CA  CB   sing N N 269 
ILE   CA  HA   sing N N 270 
ILE   C   O    doub N N 271 
ILE   C   OXT  sing N N 272 
ILE   CB  CG1  sing N N 273 
ILE   CB  CG2  sing N N 274 
ILE   CB  HB   sing N N 275 
ILE   CG1 CD1  sing N N 276 
ILE   CG1 HG12 sing N N 277 
ILE   CG1 HG13 sing N N 278 
ILE   CG2 HG21 sing N N 279 
ILE   CG2 HG22 sing N N 280 
ILE   CG2 HG23 sing N N 281 
ILE   CD1 HD11 sing N N 282 
ILE   CD1 HD12 sing N N 283 
ILE   CD1 HD13 sing N N 284 
ILE   OXT HXT  sing N N 285 
LEU   N   CA   sing N N 286 
LEU   N   H    sing N N 287 
LEU   N   H2   sing N N 288 
LEU   CA  C    sing N N 289 
LEU   CA  CB   sing N N 290 
LEU   CA  HA   sing N N 291 
LEU   C   O    doub N N 292 
LEU   C   OXT  sing N N 293 
LEU   CB  CG   sing N N 294 
LEU   CB  HB2  sing N N 295 
LEU   CB  HB3  sing N N 296 
LEU   CG  CD1  sing N N 297 
LEU   CG  CD2  sing N N 298 
LEU   CG  HG   sing N N 299 
LEU   CD1 HD11 sing N N 300 
LEU   CD1 HD12 sing N N 301 
LEU   CD1 HD13 sing N N 302 
LEU   CD2 HD21 sing N N 303 
LEU   CD2 HD22 sing N N 304 
LEU   CD2 HD23 sing N N 305 
LEU   OXT HXT  sing N N 306 
LYS   N   CA   sing N N 307 
LYS   N   H    sing N N 308 
LYS   N   H2   sing N N 309 
LYS   CA  C    sing N N 310 
LYS   CA  CB   sing N N 311 
LYS   CA  HA   sing N N 312 
LYS   C   O    doub N N 313 
LYS   C   OXT  sing N N 314 
LYS   CB  CG   sing N N 315 
LYS   CB  HB2  sing N N 316 
LYS   CB  HB3  sing N N 317 
LYS   CG  CD   sing N N 318 
LYS   CG  HG2  sing N N 319 
LYS   CG  HG3  sing N N 320 
LYS   CD  CE   sing N N 321 
LYS   CD  HD2  sing N N 322 
LYS   CD  HD3  sing N N 323 
LYS   CE  NZ   sing N N 324 
LYS   CE  HE2  sing N N 325 
LYS   CE  HE3  sing N N 326 
LYS   NZ  HZ1  sing N N 327 
LYS   NZ  HZ2  sing N N 328 
LYS   NZ  HZ3  sing N N 329 
LYS   OXT HXT  sing N N 330 
MET   N   CA   sing N N 331 
MET   N   H    sing N N 332 
MET   N   H2   sing N N 333 
MET   CA  C    sing N N 334 
MET   CA  CB   sing N N 335 
MET   CA  HA   sing N N 336 
MET   C   O    doub N N 337 
MET   C   OXT  sing N N 338 
MET   CB  CG   sing N N 339 
MET   CB  HB2  sing N N 340 
MET   CB  HB3  sing N N 341 
MET   CG  SD   sing N N 342 
MET   CG  HG2  sing N N 343 
MET   CG  HG3  sing N N 344 
MET   SD  CE   sing N N 345 
MET   CE  HE1  sing N N 346 
MET   CE  HE2  sing N N 347 
MET   CE  HE3  sing N N 348 
MET   OXT HXT  sing N N 349 
PHE   N   CA   sing N N 350 
PHE   N   H    sing N N 351 
PHE   N   H2   sing N N 352 
PHE   CA  C    sing N N 353 
PHE   CA  CB   sing N N 354 
PHE   CA  HA   sing N N 355 
PHE   C   O    doub N N 356 
PHE   C   OXT  sing N N 357 
PHE   CB  CG   sing N N 358 
PHE   CB  HB2  sing N N 359 
PHE   CB  HB3  sing N N 360 
PHE   CG  CD1  doub Y N 361 
PHE   CG  CD2  sing Y N 362 
PHE   CD1 CE1  sing Y N 363 
PHE   CD1 HD1  sing N N 364 
PHE   CD2 CE2  doub Y N 365 
PHE   CD2 HD2  sing N N 366 
PHE   CE1 CZ   doub Y N 367 
PHE   CE1 HE1  sing N N 368 
PHE   CE2 CZ   sing Y N 369 
PHE   CE2 HE2  sing N N 370 
PHE   CZ  HZ   sing N N 371 
PHE   OXT HXT  sing N N 372 
PRO   N   CA   sing N N 373 
PRO   N   CD   sing N N 374 
PRO   N   H    sing N N 375 
PRO   CA  C    sing N N 376 
PRO   CA  CB   sing N N 377 
PRO   CA  HA   sing N N 378 
PRO   C   O    doub N N 379 
PRO   C   OXT  sing N N 380 
PRO   CB  CG   sing N N 381 
PRO   CB  HB2  sing N N 382 
PRO   CB  HB3  sing N N 383 
PRO   CG  CD   sing N N 384 
PRO   CG  HG2  sing N N 385 
PRO   CG  HG3  sing N N 386 
PRO   CD  HD2  sing N N 387 
PRO   CD  HD3  sing N N 388 
PRO   OXT HXT  sing N N 389 
SER   N   CA   sing N N 390 
SER   N   H    sing N N 391 
SER   N   H2   sing N N 392 
SER   CA  C    sing N N 393 
SER   CA  CB   sing N N 394 
SER   CA  HA   sing N N 395 
SER   C   O    doub N N 396 
SER   C   OXT  sing N N 397 
SER   CB  OG   sing N N 398 
SER   CB  HB2  sing N N 399 
SER   CB  HB3  sing N N 400 
SER   OG  HG   sing N N 401 
SER   OXT HXT  sing N N 402 
THR   N   CA   sing N N 403 
THR   N   H    sing N N 404 
THR   N   H2   sing N N 405 
THR   CA  C    sing N N 406 
THR   CA  CB   sing N N 407 
THR   CA  HA   sing N N 408 
THR   C   O    doub N N 409 
THR   C   OXT  sing N N 410 
THR   CB  OG1  sing N N 411 
THR   CB  CG2  sing N N 412 
THR   CB  HB   sing N N 413 
THR   OG1 HG1  sing N N 414 
THR   CG2 HG21 sing N N 415 
THR   CG2 HG22 sing N N 416 
THR   CG2 HG23 sing N N 417 
THR   OXT HXT  sing N N 418 
TRP   N   CA   sing N N 419 
TRP   N   H    sing N N 420 
TRP   N   H2   sing N N 421 
TRP   CA  C    sing N N 422 
TRP   CA  CB   sing N N 423 
TRP   CA  HA   sing N N 424 
TRP   C   O    doub N N 425 
TRP   C   OXT  sing N N 426 
TRP   CB  CG   sing N N 427 
TRP   CB  HB2  sing N N 428 
TRP   CB  HB3  sing N N 429 
TRP   CG  CD1  doub Y N 430 
TRP   CG  CD2  sing Y N 431 
TRP   CD1 NE1  sing Y N 432 
TRP   CD1 HD1  sing N N 433 
TRP   CD2 CE2  doub Y N 434 
TRP   CD2 CE3  sing Y N 435 
TRP   NE1 CE2  sing Y N 436 
TRP   NE1 HE1  sing N N 437 
TRP   CE2 CZ2  sing Y N 438 
TRP   CE3 CZ3  doub Y N 439 
TRP   CE3 HE3  sing N N 440 
TRP   CZ2 CH2  doub Y N 441 
TRP   CZ2 HZ2  sing N N 442 
TRP   CZ3 CH2  sing Y N 443 
TRP   CZ3 HZ3  sing N N 444 
TRP   CH2 HH2  sing N N 445 
TRP   OXT HXT  sing N N 446 
TYR   N   CA   sing N N 447 
TYR   N   H    sing N N 448 
TYR   N   H2   sing N N 449 
TYR   CA  C    sing N N 450 
TYR   CA  CB   sing N N 451 
TYR   CA  HA   sing N N 452 
TYR   C   O    doub N N 453 
TYR   C   OXT  sing N N 454 
TYR   CB  CG   sing N N 455 
TYR   CB  HB2  sing N N 456 
TYR   CB  HB3  sing N N 457 
TYR   CG  CD1  doub Y N 458 
TYR   CG  CD2  sing Y N 459 
TYR   CD1 CE1  sing Y N 460 
TYR   CD1 HD1  sing N N 461 
TYR   CD2 CE2  doub Y N 462 
TYR   CD2 HD2  sing N N 463 
TYR   CE1 CZ   doub Y N 464 
TYR   CE1 HE1  sing N N 465 
TYR   CE2 CZ   sing Y N 466 
TYR   CE2 HE2  sing N N 467 
TYR   CZ  OH   sing N N 468 
TYR   OH  HH   sing N N 469 
TYR   OXT HXT  sing N N 470 
VAL   N   CA   sing N N 471 
VAL   N   H    sing N N 472 
VAL   N   H2   sing N N 473 
VAL   CA  C    sing N N 474 
VAL   CA  CB   sing N N 475 
VAL   CA  HA   sing N N 476 
VAL   C   O    doub N N 477 
VAL   C   OXT  sing N N 478 
VAL   CB  CG1  sing N N 479 
VAL   CB  CG2  sing N N 480 
VAL   CB  HB   sing N N 481 
VAL   CG1 HG11 sing N N 482 
VAL   CG1 HG12 sing N N 483 
VAL   CG1 HG13 sing N N 484 
VAL   CG2 HG21 sing N N 485 
VAL   CG2 HG22 sing N N 486 
VAL   CG2 HG23 sing N N 487 
VAL   OXT HXT  sing N N 488 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7JIT 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 41 21 2' 
_space_group.name_Hall        'P 4abw 2nw' 
_space_group.IT_number        92 
_space_group.crystal_system   tetragonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9D2K 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.008851 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008851 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004468 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761  7.44341 ? ? 1.04373  23.83732 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 7.96527  ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 24.64596 5.25405 ? ? 2.14387  29.76375 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ARG   A 1 6   ? -46.16320 -4.05793 -37.78252 1.000 109.79662 ? 3   ARG   A N   1 
ATOM   2    C  CA  . ARG   A 1 6   ? -44.87988 -4.27539 -37.12233 1.000 119.54275 ? 3   ARG   A CA  1 
ATOM   3    C  C   . ARG   A 1 6   ? -44.13265 -2.95320 -36.95023 1.000 122.04750 ? 3   ARG   A C   1 
ATOM   4    O  O   . ARG   A 1 6   ? -43.94792 -2.20548 -37.91194 1.000 117.87246 ? 3   ARG   A O   1 
ATOM   5    C  CB  . ARG   A 1 6   ? -44.03254 -5.27302 -37.91494 1.000 104.76315 ? 3   ARG   A CB  1 
ATOM   6    N  N   . THR   A 1 7   ? -43.71230 -2.66620 -35.71702 1.000 117.96527 ? 4   THR   A N   1 
ATOM   7    C  CA  . THR   A 1 7   ? -43.11031 -1.38417 -35.36714 1.000 113.44067 ? 4   THR   A CA  1 
ATOM   8    C  C   . THR   A 1 7   ? -41.94250 -1.60124 -34.41772 1.000 113.69058 ? 4   THR   A C   1 
ATOM   9    O  O   . THR   A 1 7   ? -42.05337 -2.37563 -33.46275 1.000 120.20221 ? 4   THR   A O   1 
ATOM   10   C  CB  . THR   A 1 7   ? -44.12313 -0.43674 -34.70348 1.000 104.50625 ? 4   THR   A CB  1 
ATOM   11   O  OG1 . THR   A 1 7   ? -44.56718 -1.00066 -33.46282 1.000 110.30607 ? 4   THR   A OG1 1 
ATOM   12   C  CG2 . THR   A 1 7   ? -45.32415 -0.18249 -35.60618 1.000 106.01412 ? 4   THR   A CG2 1 
ATOM   13   N  N   . ILE   A 1 8   ? -40.82570 -0.92487 -34.68538 1.000 116.84526 ? 5   ILE   A N   1 
ATOM   14   C  CA  . ILE   A 1 8   ? -39.68400 -0.92236 -33.78142 1.000 117.17419 ? 5   ILE   A CA  1 
ATOM   15   C  C   . ILE   A 1 8   ? -39.44730 0.51188  -33.32332 1.000 111.23188 ? 5   ILE   A C   1 
ATOM   16   O  O   . ILE   A 1 8   ? -39.96738 1.47034  -33.90050 1.000 101.96063 ? 5   ILE   A O   1 
ATOM   17   C  CB  . ILE   A 1 8   ? -38.40654 -1.51474 -34.41674 1.000 115.47724 ? 5   ILE   A CB  1 
ATOM   18   C  CG1 . ILE   A 1 8   ? -38.09045 -0.83275 -35.74741 1.000 111.35794 ? 5   ILE   A CG1 1 
ATOM   19   C  CG2 . ILE   A 1 8   ? -38.53870 -3.02177 -34.58636 1.000 120.98624 ? 5   ILE   A CG2 1 
ATOM   20   C  CD1 . ILE   A 1 8   ? -36.76160 -1.24985 -36.33865 1.000 112.99067 ? 5   ILE   A CD1 1 
ATOM   21   N  N   . LYS   A 1 9   ? -38.65678 0.64796  -32.26206 1.000 111.49624 ? 6   LYS   A N   1 
ATOM   22   C  CA  . LYS   A 1 9   ? -38.33467 1.94008  -31.66954 1.000 110.46821 ? 6   LYS   A CA  1 
ATOM   23   C  C   . LYS   A 1 9   ? -36.85284 2.24257  -31.85430 1.000 111.88163 ? 6   LYS   A C   1 
ATOM   24   O  O   . LYS   A 1 9   ? -36.00088 1.38500  -31.59133 1.000 108.13569 ? 6   LYS   A O   1 
ATOM   25   C  CB  . LYS   A 1 9   ? -38.71399 1.95649  -30.18744 1.000 110.73996 ? 6   LYS   A CB  1 
ATOM   26   C  CG  . LYS   A 1 9   ? -38.24506 3.17780  -29.42171 1.000 114.80903 ? 6   LYS   A CG  1 
ATOM   27   C  CD  . LYS   A 1 9   ? -38.40442 2.96774  -27.92299 1.000 124.91328 ? 6   LYS   A CD  1 
ATOM   28   C  CE  . LYS   A 1 9   ? -37.80204 4.11489  -27.12705 1.000 125.82729 ? 6   LYS   A CE  1 
ATOM   29   N  NZ  . LYS   A 1 9   ? -37.87044 3.86252  -25.66030 1.000 114.51539 ? 6   LYS   A NZ  1 
ATOM   30   N  N   . VAL   A 1 10  ? -36.54807 3.46027  -32.30862 1.000 107.51108 ? 7   VAL   A N   1 
ATOM   31   C  CA  . VAL   A 1 10  ? -35.18933 3.89318  -32.61288 1.000 102.16871 ? 7   VAL   A CA  1 
ATOM   32   C  C   . VAL   A 1 10  ? -34.97786 5.30270  -32.06919 1.000 96.19330  ? 7   VAL   A C   1 
ATOM   33   O  O   . VAL   A 1 10  ? -35.90226 5.94404  -31.56329 1.000 97.37268  ? 7   VAL   A O   1 
ATOM   34   C  CB  . VAL   A 1 10  ? -34.89237 3.85487  -34.12728 1.000 90.82196  ? 7   VAL   A CB  1 
ATOM   35   C  CG1 . VAL   A 1 10  ? -34.91241 2.42664  -34.64177 1.000 95.95871  ? 7   VAL   A CG1 1 
ATOM   36   C  CG2 . VAL   A 1 10  ? -35.89669 4.71479  -34.88216 1.000 90.81793  ? 7   VAL   A CG2 1 
ATOM   37   N  N   . PHE   A 1 11  ? -33.74161 5.78487  -32.18915 1.000 94.25269  ? 8   PHE   A N   1 
ATOM   38   C  CA  . PHE   A 1 11  ? -33.36846 7.15237  -31.84701 1.000 85.18489  ? 8   PHE   A CA  1 
ATOM   39   C  C   . PHE   A 1 11  ? -32.96595 7.90765  -33.10757 1.000 84.53043  ? 8   PHE   A C   1 
ATOM   40   O  O   . PHE   A 1 11  ? -32.20322 7.38888  -33.93014 1.000 81.05097  ? 8   PHE   A O   1 
ATOM   41   C  CB  . PHE   A 1 11  ? -32.19759 7.18903  -30.85956 1.000 89.54403  ? 8   PHE   A CB  1 
ATOM   42   C  CG  . PHE   A 1 11  ? -32.52812 6.69387  -29.48160 1.000 98.55944  ? 8   PHE   A CG  1 
ATOM   43   C  CD1 . PHE   A 1 11  ? -33.13253 7.53146  -28.55853 1.000 95.26872  ? 8   PHE   A CD1 1 
ATOM   44   C  CD2 . PHE   A 1 11  ? -32.19745 5.40518  -29.09490 1.000 97.20174  ? 8   PHE   A CD2 1 
ATOM   45   C  CE1 . PHE   A 1 11  ? -33.42204 7.08589  -27.28337 1.000 100.38530 ? 8   PHE   A CE1 1 
ATOM   46   C  CE2 . PHE   A 1 11  ? -32.48551 4.95403  -27.82124 1.000 93.26885  ? 8   PHE   A CE2 1 
ATOM   47   C  CZ  . PHE   A 1 11  ? -33.09950 5.79547  -26.91457 1.000 101.05080 ? 8   PHE   A CZ  1 
ATOM   48   N  N   . THR   A 1 12  ? -33.47794 9.12611  -33.25625 1.000 79.42399  ? 9   THR   A N   1 
ATOM   49   C  CA  . THR   A 1 12  ? -33.03368 10.04782 -34.29012 1.000 72.63657  ? 9   THR   A CA  1 
ATOM   50   C  C   . THR   A 1 12  ? -32.32247 11.22920 -33.64120 1.000 76.97519  ? 9   THR   A C   1 
ATOM   51   O  O   . THR   A 1 12  ? -32.68149 11.66269 -32.54321 1.000 73.73613  ? 9   THR   A O   1 
ATOM   52   C  CB  . THR   A 1 12  ? -34.20234 10.54553 -35.14828 1.000 65.86612  ? 9   THR   A CB  1 
ATOM   53   O  OG1 . THR   A 1 12  ? -35.19215 11.15687 -34.31191 1.000 78.00261  ? 9   THR   A OG1 1 
ATOM   54   C  CG2 . THR   A 1 12  ? -34.83089 9.38946  -35.91156 1.000 75.36729  ? 9   THR   A CG2 1 
ATOM   55   N  N   . THR   A 1 13  ? -31.30607 11.74780 -34.32490 1.000 74.93262  ? 10  THR   A N   1 
ATOM   56   C  CA  . THR   A 1 13  ? -30.51145 12.83626 -33.77260 1.000 65.23851  ? 10  THR   A CA  1 
ATOM   57   C  C   . THR   A 1 13  ? -29.85512 13.60009 -34.91109 1.000 63.65643  ? 10  THR   A C   1 
ATOM   58   O  O   . THR   A 1 13  ? -29.80956 13.14002 -36.05290 1.000 64.99196  ? 10  THR   A O   1 
ATOM   59   C  CB  . THR   A 1 13  ? -29.45156 12.31610 -32.79431 1.000 64.97203  ? 10  THR   A CB  1 
ATOM   60   O  OG1 . THR   A 1 13  ? -28.83845 13.41930 -32.11526 1.000 67.63489  ? 10  THR   A OG1 1 
ATOM   61   C  CG2 . THR   A 1 13  ? -28.38031 11.53916 -33.54047 1.000 63.36260  ? 10  THR   A CG2 1 
ATOM   62   N  N   . VAL   A 1 14  ? -29.35502 14.78679 -34.58077 1.000 61.60177  ? 11  VAL   A N   1 
ATOM   63   C  CA  . VAL   A 1 14  ? -28.48469 15.52842 -35.48190 1.000 63.43544  ? 11  VAL   A CA  1 
ATOM   64   C  C   . VAL   A 1 14  ? -27.10062 15.76131 -34.89682 1.000 62.30556  ? 11  VAL   A C   1 
ATOM   65   O  O   . VAL   A 1 14  ? -26.16779 16.06484 -35.65857 1.000 67.32212  ? 11  VAL   A O   1 
ATOM   66   C  CB  . VAL   A 1 14  ? -29.11680 16.87563 -35.89536 1.000 58.45391  ? 11  VAL   A CB  1 
ATOM   67   C  CG1 . VAL   A 1 14  ? -30.48142 16.65306 -36.50966 1.000 61.54725  ? 11  VAL   A CG1 1 
ATOM   68   C  CG2 . VAL   A 1 14  ? -29.21300 17.81199 -34.70399 1.000 61.99043  ? 11  VAL   A CG2 1 
ATOM   69   N  N   . ASP   A 1 15  ? -26.92372 15.62992 -33.58180 1.000 62.16817  ? 12  ASP   A N   1 
ATOM   70   C  CA  . ASP   A 1 15  ? -25.64265 15.86395 -32.93437 1.000 63.32801  ? 12  ASP   A CA  1 
ATOM   71   C  C   . ASP   A 1 15  ? -25.13486 14.67000 -32.13829 1.000 60.90241  ? 12  ASP   A C   1 
ATOM   72   O  O   . ASP   A 1 15  ? -24.04064 14.75059 -31.56688 1.000 64.83899  ? 12  ASP   A O   1 
ATOM   73   C  CB  . ASP   A 1 15  ? -25.73367 17.09331 -32.01979 1.000 63.37453  ? 12  ASP   A CB  1 
ATOM   74   C  CG  . ASP   A 1 15  ? -26.91166 17.02976 -31.07008 1.000 64.92499  ? 12  ASP   A CG  1 
ATOM   75   O  OD1 . ASP   A 1 15  ? -27.41067 15.91672 -30.80027 1.000 60.37639  ? 12  ASP   A OD1 1 
ATOM   76   O  OD2 . ASP   A 1 15  ? -27.34535 18.10135 -30.59985 1.000 66.22385  ? 12  ASP   A OD2 1 
ATOM   77   N  N   . ASN   A 1 16  ? -25.89991 13.57804 -32.07054 1.000 60.77780  ? 13  ASN   A N   1 
ATOM   78   C  CA  . ASN   A 1 16  ? -25.55784 12.40489 -31.26230 1.000 69.62093  ? 13  ASN   A CA  1 
ATOM   79   C  C   . ASN   A 1 16  ? -25.41724 12.75922 -29.78491 1.000 67.15747  ? 13  ASN   A C   1 
ATOM   80   O  O   . ASN   A 1 16  ? -24.72074 12.07439 -29.03092 1.000 64.14064  ? 13  ASN   A O   1 
ATOM   81   C  CB  . ASN   A 1 16  ? -24.28593 11.72221 -31.77385 1.000 69.48118  ? 13  ASN   A CB  1 
ATOM   82   C  CG  . ASN   A 1 16  ? -24.16182 10.29116 -31.29747 1.000 70.34077  ? 13  ASN   A CG  1 
ATOM   83   O  OD1 . ASN   A 1 16  ? -25.11224 9.71833  -30.76482 1.000 78.72179  ? 13  ASN   A OD1 1 
ATOM   84   N  ND2 . ASN   A 1 16  ? -22.98763 9.70316  -31.49046 1.000 77.70994  ? 13  ASN   A ND2 1 
ATOM   85   N  N   . ILE   A 1 17  ? -26.08908 13.82882 -29.36394 1.000 70.93431  ? 14  ILE   A N   1 
ATOM   86   C  CA  . ILE   A 1 17  ? -26.08233 14.26808 -27.97404 1.000 69.83852  ? 14  ILE   A CA  1 
ATOM   87   C  C   . ILE   A 1 17  ? -27.52406 14.31291 -27.49027 1.000 68.86539  ? 14  ILE   A C   1 
ATOM   88   O  O   . ILE   A 1 17  ? -27.88632 13.64812 -26.51376 1.000 73.69504  ? 14  ILE   A O   1 
ATOM   89   C  CB  . ILE   A 1 17  ? -25.39937 15.64006 -27.82444 1.000 69.95141  ? 14  ILE   A CB  1 
ATOM   90   C  CG1 . ILE   A 1 17  ? -23.88817 15.51021 -28.02926 1.000 66.92606  ? 14  ILE   A CG1 1 
ATOM   91   C  CG2 . ILE   A 1 17  ? -25.71409 16.25204 -26.46784 1.000 60.03917  ? 14  ILE   A CG2 1 
ATOM   92   C  CD1 . ILE   A 1 17  ? -23.14932 16.82870 -27.97083 1.000 69.53275  ? 14  ILE   A CD1 1 
ATOM   93   N  N   . ASN   A 1 18  ? -28.35546 15.09170 -28.17787 1.000 70.19443  ? 15  ASN   A N   1 
ATOM   94   C  CA  . ASN   A 1 18  ? -29.79301 15.13143 -27.92070 1.000 72.16906  ? 15  ASN   A CA  1 
ATOM   95   C  C   . ASN   A 1 18  ? -30.45289 14.06006 -28.78223 1.000 75.77255  ? 15  ASN   A C   1 
ATOM   96   O  O   . ASN   A 1 18  ? -30.62056 14.23480 -29.99188 1.000 69.35485  ? 15  ASN   A O   1 
ATOM   97   C  CB  . ASN   A 1 18  ? -30.35322 16.51841 -28.21633 1.000 71.82603  ? 15  ASN   A CB  1 
ATOM   98   C  CG  . ASN   A 1 18  ? -29.69366 17.60161 -27.38566 1.000 77.22078  ? 15  ASN   A CG  1 
ATOM   99   O  OD1 . ASN   A 1 18  ? -30.19986 17.98755 -26.33198 1.000 90.52972  ? 15  ASN   A OD1 1 
ATOM   100  N  ND2 . ASN   A 1 18  ? -28.55303 18.09454 -27.85444 1.000 72.52753  ? 15  ASN   A ND2 1 
ATOM   101  N  N   . LEU   A 1 19  ? -30.82757 12.94503 -28.16000 1.000 83.21108  ? 16  LEU   A N   1 
ATOM   102  C  CA  . LEU   A 1 19  ? -31.49671 11.85605 -28.85982 1.000 74.53741  ? 16  LEU   A CA  1 
ATOM   103  C  C   . LEU   A 1 19  ? -33.00770 11.99098 -28.72194 1.000 77.21334  ? 16  LEU   A C   1 
ATOM   104  O  O   . LEU   A 1 19  ? -33.51351 12.41701 -27.68027 1.000 90.20534  ? 16  LEU   A O   1 
ATOM   105  C  CB  . LEU   A 1 19  ? -31.04105 10.50156 -28.31510 1.000 69.66370  ? 16  LEU   A CB  1 
ATOM   106  C  CG  . LEU   A 1 19  ? -29.52948 10.28053 -28.24006 1.000 71.95565  ? 16  LEU   A CG  1 
ATOM   107  C  CD1 . LEU   A 1 19  ? -29.21625 8.84809  -27.83501 1.000 74.93521  ? 16  LEU   A CD1 1 
ATOM   108  C  CD2 . LEU   A 1 19  ? -28.85803 10.63334 -29.56175 1.000 79.63915  ? 16  LEU   A CD2 1 
ATOM   109  N  N   . HIS   A 1 20  ? -33.72443 11.63405 -29.78428 1.000 79.39422  ? 17  HIS   A N   1 
ATOM   110  C  CA  . HIS   A 1 20  ? -35.17811 11.73187 -29.82418 1.000 83.04077  ? 17  HIS   A CA  1 
ATOM   111  C  C   . HIS   A 1 20  ? -35.76392 10.36827 -30.16176 1.000 93.10865  ? 17  HIS   A C   1 
ATOM   112  O  O   . HIS   A 1 20  ? -35.48076 9.81475  -31.22983 1.000 91.60296  ? 17  HIS   A O   1 
ATOM   113  C  CB  . HIS   A 1 20  ? -35.62651 12.78286 -30.84296 1.000 78.54113  ? 17  HIS   A CB  1 
ATOM   114  C  CG  . HIS   A 1 20  ? -35.03443 14.13976 -30.61313 1.000 85.52130  ? 17  HIS   A CG  1 
ATOM   115  N  ND1 . HIS   A 1 20  ? -35.66467 15.10958 -29.86318 1.000 98.66330  ? 17  HIS   A ND1 1 
ATOM   116  C  CD2 . HIS   A 1 20  ? -33.86822 14.68747 -31.03101 1.000 82.62112  ? 17  HIS   A CD2 1 
ATOM   117  C  CE1 . HIS   A 1 20  ? -34.91399 16.19655 -29.83061 1.000 91.86584  ? 17  HIS   A CE1 1 
ATOM   118  N  NE2 . HIS   A 1 20  ? -33.81804 15.96645 -30.53120 1.000 84.63778  ? 17  HIS   A NE2 1 
ATOM   119  N  N   . THR   A 1 21  ? -36.57195 9.83104  -29.24939 1.000 105.05659 ? 18  THR   A N   1 
ATOM   120  C  CA  . THR   A 1 21  ? -37.21512 8.54172  -29.46729 1.000 99.75714  ? 18  THR   A CA  1 
ATOM   121  C  C   . THR   A 1 21  ? -38.28506 8.64945  -30.54832 1.000 96.04103  ? 18  THR   A C   1 
ATOM   122  O  O   . THR   A 1 21  ? -39.04762 9.61827  -30.59671 1.000 98.40578  ? 18  THR   A O   1 
ATOM   123  C  CB  . THR   A 1 21  ? -37.83483 8.02786  -28.16680 1.000 107.81155 ? 18  THR   A CB  1 
ATOM   124  O  OG1 . THR   A 1 21  ? -38.85486 8.93587  -27.73349 1.000 108.04296 ? 18  THR   A OG1 1 
ATOM   125  C  CG2 . THR   A 1 21  ? -36.77970 7.90349  -27.07731 1.000 98.72826  ? 18  THR   A CG2 1 
ATOM   126  N  N   . GLN   A 1 22  ? -38.33440 7.64458  -31.42169 1.000 98.83078  ? 19  GLN   A N   1 
ATOM   127  C  CA  . GLN   A 1 22  ? -39.27253 7.61378  -32.53506 1.000 105.03290 ? 19  GLN   A CA  1 
ATOM   128  C  C   . GLN   A 1 22  ? -39.81692 6.20519  -32.71945 1.000 105.58984 ? 19  GLN   A C   1 
ATOM   129  O  O   . GLN   A 1 22  ? -39.14780 5.21666  -32.40595 1.000 98.77695  ? 19  GLN   A O   1 
ATOM   130  C  CB  . GLN   A 1 22  ? -38.62589 8.08639  -33.84563 1.000 96.35828  ? 19  GLN   A CB  1 
ATOM   131  C  CG  . GLN   A 1 22  ? -38.12368 9.51675  -33.82415 1.000 93.90686  ? 19  GLN   A CG  1 
ATOM   132  C  CD  . GLN   A 1 22  ? -39.25579 10.51944 -33.74410 1.000 97.49487  ? 19  GLN   A CD  1 
ATOM   133  O  OE1 . GLN   A 1 22  ? -40.22948 10.43286 -34.49350 1.000 102.69416 ? 19  GLN   A OE1 1 
ATOM   134  N  NE2 . GLN   A 1 22  ? -39.13653 11.47668 -32.83263 1.000 102.65818 ? 19  GLN   A NE2 1 
ATOM   135  N  N   . VAL   A 1 23  ? -41.04871 6.12692  -33.22037 1.000 105.39453 ? 20  VAL   A N   1 
ATOM   136  C  CA  . VAL   A 1 23  ? -41.66068 4.86875  -33.63127 1.000 106.95564 ? 20  VAL   A CA  1 
ATOM   137  C  C   . VAL   A 1 23  ? -41.66409 4.83114  -35.15278 1.000 108.74214 ? 20  VAL   A C   1 
ATOM   138  O  O   . VAL   A 1 23  ? -41.98758 5.83059  -35.80674 1.000 107.31865 ? 20  VAL   A O   1 
ATOM   139  C  CB  . VAL   A 1 23  ? -43.08426 4.71224  -33.06433 1.000 103.21521 ? 20  VAL   A CB  1 
ATOM   140  C  CG1 . VAL   A 1 23  ? -43.03830 4.57818  -31.55199 1.000 94.62218  ? 20  VAL   A CG1 1 
ATOM   141  C  CG2 . VAL   A 1 23  ? -43.96837 5.89095  -33.46878 1.000 104.49748 ? 20  VAL   A CG2 1 
ATOM   142  N  N   . VAL   A 1 24  ? -41.27854 3.69032  -35.71546 1.000 106.82389 ? 21  VAL   A N   1 
ATOM   143  C  CA  . VAL   A 1 24  ? -41.09073 3.55743  -37.15360 1.000 114.14710 ? 21  VAL   A CA  1 
ATOM   144  C  C   . VAL   A 1 24  ? -41.80334 2.29687  -37.62510 1.000 117.82560 ? 21  VAL   A C   1 
ATOM   145  O  O   . VAL   A 1 24  ? -41.67841 1.23562  -37.00293 1.000 115.20465 ? 21  VAL   A O   1 
ATOM   146  C  CB  . VAL   A 1 24  ? -39.59409 3.53453  -37.53216 1.000 107.58077 ? 21  VAL   A CB  1 
ATOM   147  C  CG1 . VAL   A 1 24  ? -38.83291 2.50084  -36.71635 1.000 98.99802  ? 21  VAL   A CG1 1 
ATOM   148  C  CG2 . VAL   A 1 24  ? -39.41910 3.28001  -39.01424 1.000 104.31392 ? 21  VAL   A CG2 1 
ATOM   149  N  N   . ASP   A 1 25  ? -42.55988 2.41919  -38.71355 1.000 117.06793 ? 22  ASP   A N   1 
ATOM   150  C  CA  . ASP   A 1 25  ? -43.22845 1.27354  -39.31377 1.000 116.74651 ? 22  ASP   A CA  1 
ATOM   151  C  C   . ASP   A 1 25  ? -42.22448 0.46353  -40.12611 1.000 118.31794 ? 22  ASP   A C   1 
ATOM   152  O  O   . ASP   A 1 25  ? -41.54626 1.00445  -41.00598 1.000 120.37718 ? 22  ASP   A O   1 
ATOM   153  C  CB  . ASP   A 1 25  ? -44.38352 1.74128  -40.19946 1.000 116.92203 ? 22  ASP   A CB  1 
ATOM   154  C  CG  . ASP   A 1 25  ? -45.16754 0.59036  -40.79852 1.000 124.80653 ? 22  ASP   A CG  1 
ATOM   155  O  OD1 . ASP   A 1 25  ? -44.97112 -0.56535 -40.36423 1.000 127.23071 ? 22  ASP   A OD1 1 
ATOM   156  O  OD2 . ASP   A 1 25  ? -45.98796 0.84404  -41.70503 1.000 126.41443 ? 22  ASP   A OD2 1 
ATOM   157  N  N   . MET   A 1 26  ? -42.13679 -0.83777 -39.83716 1.000 113.22074 ? 23  MET   A N   1 
ATOM   158  C  CA  . MET   A 1 26  ? -41.16959 -1.69819 -40.51166 1.000 111.30318 ? 23  MET   A CA  1 
ATOM   159  C  C   . MET   A 1 26  ? -41.52532 -1.97525 -41.96804 1.000 112.44838 ? 23  MET   A C   1 
ATOM   160  O  O   . MET   A 1 26  ? -40.72718 -2.60552 -42.67065 1.000 109.52652 ? 23  MET   A O   1 
ATOM   161  C  CB  . MET   A 1 26  ? -41.01588 -3.01467 -39.75028 1.000 101.14118 ? 23  MET   A CB  1 
ATOM   162  C  CG  . MET   A 1 26  ? -40.49672 -2.83348 -38.33476 1.000 103.51421 ? 23  MET   A CG  1 
ATOM   163  S  SD  . MET   A 1 26  ? -40.03985 -4.38391 -37.53750 1.000 134.48670 ? 23  MET   A SD  1 
ATOM   164  C  CE  . MET   A 1 26  ? -38.53766 -4.80449 -38.41813 1.000 115.25795 ? 23  MET   A CE  1 
ATOM   165  N  N   . SER   A 1 27  ? -42.68967 -1.52614 -42.43753 1.000 116.24180 ? 24  SER   A N   1 
ATOM   166  C  CA  . SER   A 1 27  ? -43.10642 -1.73970 -43.81678 1.000 116.40542 ? 24  SER   A CA  1 
ATOM   167  C  C   . SER   A 1 27  ? -42.81520 -0.54464 -44.71460 1.000 114.76123 ? 24  SER   A C   1 
ATOM   168  O  O   . SER   A 1 27  ? -42.95138 -0.65979 -45.93744 1.000 112.38176 ? 24  SER   A O   1 
ATOM   169  C  CB  . SER   A 1 27  ? -44.60458 -2.06380 -43.87701 1.000 121.18712 ? 24  SER   A CB  1 
ATOM   170  O  OG  . SER   A 1 27  ? -45.38234 -0.96722 -43.42803 1.000 123.65468 ? 24  SER   A OG  1 
ATOM   171  N  N   . MET   A 1 28  ? -42.42274 0.58886  -44.14147 1.000 116.91270 ? 25  MET   A N   1 
ATOM   172  C  CA  . MET   A 1 28  ? -42.08268 1.78944  -44.88757 1.000 112.79549 ? 25  MET   A CA  1 
ATOM   173  C  C   . MET   A 1 28  ? -40.58856 2.05657  -44.76921 1.000 110.25401 ? 25  MET   A C   1 
ATOM   174  O  O   . MET   A 1 28  ? -39.96936 1.75056  -43.74753 1.000 107.40513 ? 25  MET   A O   1 
ATOM   175  C  CB  . MET   A 1 28  ? -42.85940 2.99871  -44.36194 1.000 108.12710 ? 25  MET   A CB  1 
ATOM   176  C  CG  . MET   A 1 28  ? -44.35495 2.78633  -44.26151 1.000 112.28236 ? 25  MET   A CG  1 
ATOM   177  S  SD  . MET   A 1 28  ? -45.17452 4.19400  -43.49060 1.000 131.55711 ? 25  MET   A SD  1 
ATOM   178  C  CE  . MET   A 1 28  ? -44.72579 5.51114  -44.61954 1.000 106.70831 ? 25  MET   A CE  1 
ATOM   179  N  N   . THR   A 1 29  ? -40.01120 2.63639  -45.81750 1.000 102.65521 ? 26  THR   A N   1 
ATOM   180  C  CA  . THR   A 1 29  ? -38.60604 3.00477  -45.75476 1.000 104.26066 ? 26  THR   A CA  1 
ATOM   181  C  C   . THR   A 1 29  ? -38.40430 4.16336  -44.77973 1.000 104.33227 ? 26  THR   A C   1 
ATOM   182  O  O   . THR   A 1 29  ? -39.34199 4.88272  -44.42014 1.000 102.75197 ? 26  THR   A O   1 
ATOM   183  C  CB  . THR   A 1 29  ? -38.07863 3.38649  -47.13862 1.000 94.32164  ? 26  THR   A CB  1 
ATOM   184  O  OG1 . THR   A 1 29  ? -38.79959 4.52320  -47.63138 1.000 91.75699  ? 26  THR   A OG1 1 
ATOM   185  C  CG2 . THR   A 1 29  ? -38.23212 2.22424  -48.11020 1.000 94.96050  ? 26  THR   A CG2 1 
ATOM   186  N  N   . TYR   A 1 30  ? -37.15263 4.33648  -44.34629 1.000 94.41537  ? 27  TYR   A N   1 
ATOM   187  C  CA  . TYR   A 1 30  ? -36.83830 5.42104  -43.42200 1.000 83.00554  ? 27  TYR   A CA  1 
ATOM   188  C  C   . TYR   A 1 30  ? -37.11661 6.78523  -44.03715 1.000 87.22210  ? 27  TYR   A C   1 
ATOM   189  O  O   . TYR   A 1 30  ? -37.51386 7.71608  -43.32652 1.000 83.63936  ? 27  TYR   A O   1 
ATOM   190  C  CB  . TYR   A 1 30  ? -35.37984 5.33232  -42.97646 1.000 74.26397  ? 27  TYR   A CB  1 
ATOM   191  C  CG  . TYR   A 1 30  ? -35.11185 4.27054  -41.93392 1.000 75.09959  ? 27  TYR   A CG  1 
ATOM   192  C  CD1 . TYR   A 1 30  ? -35.61560 4.39508  -40.64516 1.000 73.28791  ? 27  TYR   A CD1 1 
ATOM   193  C  CD2 . TYR   A 1 30  ? -34.34627 3.14992  -42.23176 1.000 75.93656  ? 27  TYR   A CD2 1 
ATOM   194  C  CE1 . TYR   A 1 30  ? -35.37065 3.43021  -39.68173 1.000 80.37968  ? 27  TYR   A CE1 1 
ATOM   195  C  CE2 . TYR   A 1 30  ? -34.09547 2.17814  -41.27439 1.000 79.53133  ? 27  TYR   A CE2 1 
ATOM   196  C  CZ  . TYR   A 1 30  ? -34.61056 2.32348  -40.00055 1.000 81.87314  ? 27  TYR   A CZ  1 
ATOM   197  O  OH  . TYR   A 1 30  ? -34.36627 1.36245  -39.04190 1.000 85.24346  ? 27  TYR   A OH  1 
ATOM   198  N  N   . GLY   A 1 31  ? -36.91523 6.92507  -45.34976 1.000 86.00467  ? 28  GLY   A N   1 
ATOM   199  C  CA  . GLY   A 1 31  ? -37.14532 8.20619  -45.99304 1.000 81.62040  ? 28  GLY   A CA  1 
ATOM   200  C  C   . GLY   A 1 31  ? -38.59738 8.63298  -45.98589 1.000 88.80198  ? 28  GLY   A C   1 
ATOM   201  O  O   . GLY   A 1 31  ? -38.89378 9.83092  -45.96138 1.000 91.18182  ? 28  GLY   A O   1 
ATOM   202  N  N   . GLN   A 1 32  ? -39.52003 7.66901  -46.00937 1.000 97.49750  ? 29  GLN   A N   1 
ATOM   203  C  CA  . GLN   A 1 32  ? -40.94118 7.99242  -45.98816 1.000 102.05106 ? 29  GLN   A CA  1 
ATOM   204  C  C   . GLN   A 1 32  ? -41.41281 8.45048  -44.61453 1.000 97.52904  ? 29  GLN   A C   1 
ATOM   205  O  O   . GLN   A 1 32  ? -42.50021 9.02652  -44.50644 1.000 101.39619 ? 29  GLN   A O   1 
ATOM   206  C  CB  . GLN   A 1 32  ? -41.75553 6.78055  -46.44215 1.000 105.00088 ? 29  GLN   A CB  1 
ATOM   207  C  CG  . GLN   A 1 32  ? -41.51284 6.37986  -47.88939 1.000 102.44324 ? 29  GLN   A CG  1 
ATOM   208  C  CD  . GLN   A 1 32  ? -42.00681 4.98029  -48.19653 1.000 107.11423 ? 29  GLN   A CD  1 
ATOM   209  O  OE1 . GLN   A 1 32  ? -42.19188 4.16336  -47.29441 1.000 106.64940 ? 29  GLN   A OE1 1 
ATOM   210  N  NE2 . GLN   A 1 32  ? -42.21973 4.69493  -49.47645 1.000 106.40278 ? 29  GLN   A NE2 1 
ATOM   211  N  N   . GLN   A 1 33  ? -40.62427 8.21510  -43.57049 1.000 92.82823  ? 30  GLN   A N   1 
ATOM   212  C  CA  . GLN   A 1 33  ? -41.00571 8.56515  -42.21022 1.000 98.61147  ? 30  GLN   A CA  1 
ATOM   213  C  C   . GLN   A 1 33  ? -40.08628 9.58329  -41.55406 1.000 97.78758  ? 30  GLN   A C   1 
ATOM   214  O  O   . GLN   A 1 33  ? -40.55186 10.36076 -40.71797 1.000 101.81245 ? 30  GLN   A O   1 
ATOM   215  C  CB  . GLN   A 1 33  ? -41.05818 7.30108  -41.33957 1.000 96.13463  ? 30  GLN   A CB  1 
ATOM   216  C  CG  . GLN   A 1 33  ? -41.84384 6.16885  -41.97635 1.000 102.32164 ? 30  GLN   A CG  1 
ATOM   217  C  CD  . GLN   A 1 33  ? -41.53968 4.82354  -41.35314 1.000 110.60740 ? 30  GLN   A CD  1 
ATOM   218  O  OE1 . GLN   A 1 33  ? -42.13008 4.44744  -40.34039 1.000 114.13726 ? 30  GLN   A OE1 1 
ATOM   219  N  NE2 . GLN   A 1 33  ? -40.61612 4.08625  -41.96047 1.000 102.95240 ? 30  GLN   A NE2 1 
ATOM   220  N  N   . PHE   A 1 34  ? -38.80001 9.60195  -41.90583 1.000 92.91654  ? 31  PHE   A N   1 
ATOM   221  C  CA  . PHE   A 1 34  ? -37.84601 10.53270 -41.32400 1.000 84.64788  ? 31  PHE   A CA  1 
ATOM   222  C  C   . PHE   A 1 34  ? -37.19668 11.45344 -42.34345 1.000 85.40198  ? 31  PHE   A C   1 
ATOM   223  O  O   . PHE   A 1 34  ? -36.54036 12.42191 -41.94334 1.000 91.60799  ? 31  PHE   A O   1 
ATOM   224  C  CB  . PHE   A 1 34  ? -36.72676 9.77805  -40.58746 1.000 80.30347  ? 31  PHE   A CB  1 
ATOM   225  C  CG  . PHE   A 1 34  ? -37.19601 8.97843  -39.40761 1.000 84.84175  ? 31  PHE   A CG  1 
ATOM   226  C  CD1 . PHE   A 1 34  ? -38.30418 9.37015  -38.67695 1.000 85.83739  ? 31  PHE   A CD1 1 
ATOM   227  C  CD2 . PHE   A 1 34  ? -36.51014 7.83928  -39.01748 1.000 84.08690  ? 31  PHE   A CD2 1 
ATOM   228  C  CE1 . PHE   A 1 34  ? -38.72685 8.63149  -37.58735 1.000 100.82505 ? 31  PHE   A CE1 1 
ATOM   229  C  CE2 . PHE   A 1 34  ? -36.92614 7.09826  -37.93009 1.000 89.76565  ? 31  PHE   A CE2 1 
ATOM   230  C  CZ  . PHE   A 1 34  ? -38.03572 7.49361  -37.21453 1.000 98.18317  ? 31  PHE   A CZ  1 
ATOM   231  N  N   . GLY   A 1 35  ? -37.36022 11.19112 -43.63646 1.000 87.29980  ? 32  GLY   A N   1 
ATOM   232  C  CA  . GLY   A 1 35  ? -36.57627 11.85545 -44.64811 1.000 76.06056  ? 32  GLY   A CA  1 
ATOM   233  C  C   . GLY   A 1 35  ? -35.23419 11.17013 -44.78351 1.000 77.02330  ? 32  GLY   A C   1 
ATOM   234  O  O   . GLY   A 1 35  ? -35.07612 10.00162 -44.41450 1.000 81.40185  ? 32  GLY   A O   1 
ATOM   235  N  N   . PRO   A 1 36  ? -34.23995 11.87817 -45.31634 1.000 71.78967  ? 33  PRO   A N   1 
ATOM   236  C  CA  . PRO   A 1 36  ? -32.88997 11.30253 -45.39792 1.000 70.55099  ? 33  PRO   A CA  1 
ATOM   237  C  C   . PRO   A 1 36  ? -32.40318 10.85684 -44.02388 1.000 66.96651  ? 33  PRO   A C   1 
ATOM   238  O  O   . PRO   A 1 36  ? -32.43280 11.62107 -43.05687 1.000 67.87870  ? 33  PRO   A O   1 
ATOM   239  C  CB  . PRO   A 1 36  ? -32.04871 12.45335 -45.95880 1.000 62.25124  ? 33  PRO   A CB  1 
ATOM   240  C  CG  . PRO   A 1 36  ? -33.03068 13.30560 -46.70052 1.000 54.51401  ? 33  PRO   A CG  1 
ATOM   241  C  CD  . PRO   A 1 36  ? -34.31130 13.21799 -45.92310 1.000 55.87740  ? 33  PRO   A CD  1 
ATOM   242  N  N   . THR   A 1 37  ? -31.96960 9.59919  -43.94311 1.000 60.22953  ? 34  THR   A N   1 
ATOM   243  C  CA  . THR   A 1 37  ? -31.61255 8.96843  -42.68069 1.000 67.53667  ? 34  THR   A CA  1 
ATOM   244  C  C   . THR   A 1 37  ? -30.30640 8.20722  -42.84904 1.000 69.23602  ? 34  THR   A C   1 
ATOM   245  O  O   . THR   A 1 37  ? -30.07368 7.58872  -43.89101 1.000 73.12006  ? 34  THR   A O   1 
ATOM   246  C  CB  . THR   A 1 37  ? -32.72305 8.01788  -42.21113 1.000 67.99334  ? 34  THR   A CB  1 
ATOM   247  O  OG1 . THR   A 1 37  ? -33.97198 8.72163  -42.19039 1.000 73.91906  ? 34  THR   A OG1 1 
ATOM   248  C  CG2 . THR   A 1 37  ? -32.42777 7.48280  -40.81674 1.000 68.57586  ? 34  THR   A CG2 1 
ATOM   249  N  N   . TYR   A 1 38  ? -29.45617 8.25342  -41.82134 1.000 69.64073  ? 35  TYR   A N   1 
ATOM   250  C  CA  . TYR   A 1 38  ? -28.13381 7.64854  -41.87800 1.000 58.33270  ? 35  TYR   A CA  1 
ATOM   251  C  C   . TYR   A 1 38  ? -27.85856 6.84373  -40.61611 1.000 66.06263  ? 35  TYR   A C   1 
ATOM   252  O  O   . TYR   A 1 38  ? -28.31283 7.19219  -39.52371 1.000 69.59270  ? 35  TYR   A O   1 
ATOM   253  C  CB  . TYR   A 1 38  ? -27.04405 8.71260  -42.06186 1.000 58.78590  ? 35  TYR   A CB  1 
ATOM   254  C  CG  . TYR   A 1 38  ? -27.29152 9.63272  -43.23608 1.000 65.80772  ? 35  TYR   A CG  1 
ATOM   255  C  CD1 . TYR   A 1 38  ? -28.07274 10.77407 -43.09916 1.000 60.01351  ? 35  TYR   A CD1 1 
ATOM   256  C  CD2 . TYR   A 1 38  ? -26.75511 9.35295  -44.48582 1.000 60.03499  ? 35  TYR   A CD2 1 
ATOM   257  C  CE1 . TYR   A 1 38  ? -28.30522 11.61392 -44.17517 1.000 58.30218  ? 35  TYR   A CE1 1 
ATOM   258  C  CE2 . TYR   A 1 38  ? -26.98198 10.18609 -45.56442 1.000 55.97020  ? 35  TYR   A CE2 1 
ATOM   259  C  CZ  . TYR   A 1 38  ? -27.75706 11.31523 -45.40530 1.000 64.07082  ? 35  TYR   A CZ  1 
ATOM   260  O  OH  . TYR   A 1 38  ? -27.98341 12.14675 -46.48159 1.000 71.94094  ? 35  TYR   A OH  1 
ATOM   261  N  N   . LEU   A 1 39  ? -27.09874 5.76145  -40.78365 1.000 69.88651  ? 36  LEU   A N   1 
ATOM   262  C  CA  . LEU   A 1 39  ? -26.65942 4.90166  -39.68650 1.000 69.08226  ? 36  LEU   A CA  1 
ATOM   263  C  C   . LEU   A 1 39  ? -25.14893 4.73770  -39.78381 1.000 77.48077  ? 36  LEU   A C   1 
ATOM   264  O  O   . LEU   A 1 39  ? -24.65793 4.01238  -40.65561 1.000 76.86846  ? 36  LEU   A O   1 
ATOM   265  C  CB  . LEU   A 1 39  ? -27.35721 3.54253  -39.73134 1.000 67.03863  ? 36  LEU   A CB  1 
ATOM   266  C  CG  . LEU   A 1 39  ? -27.04044 2.58522  -38.58043 1.000 74.40434  ? 36  LEU   A CG  1 
ATOM   267  C  CD1 . LEU   A 1 39  ? -27.44714 3.18191  -37.24419 1.000 84.15928  ? 36  LEU   A CD1 1 
ATOM   268  C  CD2 . LEU   A 1 39  ? -27.71912 1.24436  -38.80031 1.000 72.42991  ? 36  LEU   A CD2 1 
ATOM   269  N  N   . ASP   A 1 40  ? -24.41846 5.40709  -38.88945 1.000 76.02257  ? 37  ASP   A N   1 
ATOM   270  C  CA  . ASP   A 1 40  ? -22.95321 5.39085  -38.88752 1.000 74.81419  ? 37  ASP   A CA  1 
ATOM   271  C  C   . ASP   A 1 40  ? -22.39505 5.84937  -40.23230 1.000 76.74271  ? 37  ASP   A C   1 
ATOM   272  O  O   . ASP   A 1 40  ? -21.44716 5.26897  -40.76605 1.000 80.07980  ? 37  ASP   A O   1 
ATOM   273  C  CB  . ASP   A 1 40  ? -22.41044 4.00912  -38.51713 1.000 78.70665  ? 37  ASP   A CB  1 
ATOM   274  C  CG  . ASP   A 1 40  ? -22.45335 3.74876  -37.02510 1.000 102.30270 ? 37  ASP   A CG  1 
ATOM   275  O  OD1 . ASP   A 1 40  ? -21.90595 4.57205  -36.26057 1.000 103.00772 ? 37  ASP   A OD1 1 
ATOM   276  O  OD2 . ASP   A 1 40  ? -23.03385 2.72046  -36.61751 1.000 109.07023 ? 37  ASP   A OD2 1 
ATOM   277  N  N   . GLY   A 1 41  ? -22.98204 6.91441  -40.77855 1.000 72.91254  ? 38  GLY   A N   1 
ATOM   278  C  CA  . GLY   A 1 41  ? -22.56634 7.44984  -42.05541 1.000 64.87725  ? 38  GLY   A CA  1 
ATOM   279  C  C   . GLY   A 1 41  ? -23.16307 6.77182  -43.26684 1.000 64.55633  ? 38  GLY   A C   1 
ATOM   280  O  O   . GLY   A 1 41  ? -23.07800 7.32949  -44.36773 1.000 74.53844  ? 38  GLY   A O   1 
ATOM   281  N  N   . ALA   A 1 42  ? -23.76841 5.59675  -43.11092 1.000 68.42532  ? 39  ALA   A N   1 
ATOM   282  C  CA  . ALA   A 1 42  ? -24.35603 4.87248  -44.23054 1.000 68.79805  ? 39  ALA   A CA  1 
ATOM   283  C  C   . ALA   A 1 42  ? -25.77588 5.36353  -44.49606 1.000 67.29364  ? 39  ALA   A C   1 
ATOM   284  O  O   . ALA   A 1 42  ? -26.57513 5.50379  -43.56519 1.000 71.44746  ? 39  ALA   A O   1 
ATOM   285  C  CB  . ALA   A 1 42  ? -24.35911 3.37008  -43.95116 1.000 60.85274  ? 39  ALA   A CB  1 
ATOM   286  N  N   . ASP   A 1 43  ? -26.08532 5.61591  -45.76829 1.000 70.63782  ? 40  ASP   A N   1 
ATOM   287  C  CA  . ASP   A 1 43  ? -27.40553 6.09900  -46.16311 1.000 69.53478  ? 40  ASP   A CA  1 
ATOM   288  C  C   . ASP   A 1 43  ? -28.40474 4.94731  -46.12471 1.000 74.83754  ? 40  ASP   A C   1 
ATOM   289  O  O   . ASP   A 1 43  ? -28.24806 3.95614  -46.84746 1.000 74.26251  ? 40  ASP   A O   1 
ATOM   290  C  CB  . ASP   A 1 43  ? -27.35007 6.71656  -47.55951 1.000 69.84596  ? 40  ASP   A CB  1 
ATOM   291  C  CG  . ASP   A 1 43  ? -28.59300 7.52442  -47.89433 1.000 74.35639  ? 40  ASP   A CG  1 
ATOM   292  O  OD1 . ASP   A 1 43  ? -29.64434 7.30141  -47.25925 1.000 77.96952  ? 40  ASP   A OD1 1 
ATOM   293  O  OD2 . ASP   A 1 43  ? -28.51792 8.38752  -48.79489 1.000 71.18648  ? 40  ASP   A OD2 1 
ATOM   294  N  N   . VAL   A 1 44  ? -29.43460 5.08328  -45.28791 1.000 70.13982  ? 41  VAL   A N   1 
ATOM   295  C  CA  . VAL   A 1 44  ? -30.47223 4.06544  -45.14938 1.000 70.52919  ? 41  VAL   A CA  1 
ATOM   296  C  C   . VAL   A 1 44  ? -31.83600 4.66135  -45.47646 1.000 76.56437  ? 41  VAL   A C   1 
ATOM   297  O  O   . VAL   A 1 44  ? -32.86664 4.17806  -44.99400 1.000 82.37499  ? 41  VAL   A O   1 
ATOM   298  C  CB  . VAL   A 1 44  ? -30.46072 3.45497  -43.73517 1.000 68.88345  ? 41  VAL   A CB  1 
ATOM   299  C  CG1 . VAL   A 1 44  ? -29.13267 2.77251  -43.46835 1.000 70.68369  ? 41  VAL   A CG1 1 
ATOM   300  C  CG2 . VAL   A 1 44  ? -30.72211 4.52902  -42.69019 1.000 66.87759  ? 41  VAL   A CG2 1 
ATOM   301  N  N   . THR   A 1 45  ? -31.85050 5.71068  -46.30238 1.000 72.74049  ? 42  THR   A N   1 
ATOM   302  C  CA  . THR   A 1 45  ? -33.10572 6.37681  -46.64309 1.000 78.03472  ? 42  THR   A CA  1 
ATOM   303  C  C   . THR   A 1 45  ? -34.07577 5.42248  -47.33202 1.000 82.51461  ? 42  THR   A C   1 
ATOM   304  O  O   . THR   A 1 45  ? -35.25272 5.34134  -46.96180 1.000 87.11183  ? 42  THR   A O   1 
ATOM   305  C  CB  . THR   A 1 45  ? -32.83235 7.59126  -47.53255 1.000 76.22126  ? 42  THR   A CB  1 
ATOM   306  O  OG1 . THR   A 1 45  ? -31.95794 8.49995  -46.85307 1.000 74.16953  ? 42  THR   A OG1 1 
ATOM   307  C  CG2 . THR   A 1 45  ? -34.12528 8.30683  -47.86888 1.000 72.25748  ? 42  THR   A CG2 1 
ATOM   308  N  N   . LYS   A 1 46  ? -33.59954 4.68868  -48.33043 1.000 80.76893  ? 43  LYS   A N   1 
ATOM   309  C  CA  . LYS   A 1 46  ? -34.43368 3.75094  -49.08476 1.000 86.13427  ? 43  LYS   A CA  1 
ATOM   310  C  C   . LYS   A 1 46  ? -34.22671 2.31901  -48.60696 1.000 86.03274  ? 43  LYS   A C   1 
ATOM   311  O  O   . LYS   A 1 46  ? -34.04123 1.39069  -49.39320 1.000 89.63168  ? 43  LYS   A O   1 
ATOM   312  C  CB  . LYS   A 1 46  ? -34.15071 3.88339  -50.57675 1.000 85.51378  ? 43  LYS   A CB  1 
ATOM   313  C  CG  . LYS   A 1 46  ? -32.67975 3.77396  -50.94704 1.000 86.53419  ? 43  LYS   A CG  1 
ATOM   314  C  CD  . LYS   A 1 46  ? -32.42834 4.25775  -52.36435 1.000 82.80741  ? 43  LYS   A CD  1 
ATOM   315  C  CE  . LYS   A 1 46  ? -32.83222 5.71429  -52.52540 1.000 79.48018  ? 43  LYS   A CE  1 
ATOM   316  N  NZ  . LYS   A 1 46  ? -32.45763 6.23810  -53.86757 1.000 90.33731  ? 43  LYS   A NZ  1 
ATOM   317  N  N   . ILE   A 1 47  ? -34.26478 2.13094  -47.29154 1.000 85.95684  ? 44  ILE   A N   1 
ATOM   318  C  CA  . ILE   A 1 47  ? -34.09766 0.82516  -46.66751 1.000 89.47162  ? 44  ILE   A CA  1 
ATOM   319  C  C   . ILE   A 1 47  ? -35.20989 0.64110  -45.64618 1.000 92.54635  ? 44  ILE   A C   1 
ATOM   320  O  O   . ILE   A 1 47  ? -35.47175 1.53809  -44.83753 1.000 94.64886  ? 44  ILE   A O   1 
ATOM   321  C  CB  . ILE   A 1 47  ? -32.71157 0.68226  -46.00578 1.000 88.76021  ? 44  ILE   A CB  1 
ATOM   322  C  CG1 . ILE   A 1 47  ? -31.64025 0.40561  -47.06330 1.000 88.88499  ? 44  ILE   A CG1 1 
ATOM   323  C  CG2 . ILE   A 1 47  ? -32.71605 -0.40424 -44.93781 1.000 80.82874  ? 44  ILE   A CG2 1 
ATOM   324  C  CD1 . ILE   A 1 47  ? -30.25918 0.17131  -46.48336 1.000 94.74955  ? 44  ILE   A CD1 1 
ATOM   325  N  N   . LYS   A 1 48  ? -35.87169 -0.50972 -45.69454 1.000 99.24507  ? 45  LYS   A N   1 
ATOM   326  C  CA  . LYS   A 1 48  ? -36.89371 -0.81314 -44.71220 1.000 102.58166 ? 45  LYS   A CA  1 
ATOM   327  C  C   . LYS   A 1 48  ? -36.23097 -1.15541 -43.37716 1.000 99.68130  ? 45  LYS   A C   1 
ATOM   328  O  O   . LYS   A 1 48  ? -35.13204 -1.71687 -43.34806 1.000 101.40557 ? 45  LYS   A O   1 
ATOM   329  C  CB  . LYS   A 1 48  ? -37.75129 -1.98147 -45.19116 1.000 106.34309 ? 45  LYS   A CB  1 
ATOM   330  C  CG  . LYS   A 1 48  ? -39.05094 -1.57313 -45.86932 1.000 107.03487 ? 45  LYS   A CG  1 
ATOM   331  C  CD  . LYS   A 1 48  ? -39.47855 -2.62675 -46.88179 1.000 108.05154 ? 45  LYS   A CD  1 
ATOM   332  C  CE  . LYS   A 1 48  ? -40.40565 -2.04430 -47.93643 1.000 111.55645 ? 45  LYS   A CE  1 
ATOM   333  N  NZ  . LYS   A 1 48  ? -40.65842 -3.00977 -49.04303 1.000 116.75581 ? 45  LYS   A NZ  1 
ATOM   334  N  N   . PRO   A 1 49  ? -36.87289 -0.82362 -42.25777 1.000 94.80885  ? 46  PRO   A N   1 
ATOM   335  C  CA  . PRO   A 1 49  ? -36.25536 -1.09135 -40.95222 1.000 93.76365  ? 46  PRO   A CA  1 
ATOM   336  C  C   . PRO   A 1 49  ? -36.09065 -2.58410 -40.71732 1.000 103.57059 ? 46  PRO   A C   1 
ATOM   337  O  O   . PRO   A 1 49  ? -37.02813 -3.36609 -40.89026 1.000 111.03754 ? 46  PRO   A O   1 
ATOM   338  C  CB  . PRO   A 1 49  ? -37.24406 -0.47229 -39.95700 1.000 91.65319  ? 46  PRO   A CB  1 
ATOM   339  C  CG  . PRO   A 1 49  ? -38.03832 0.49791  -40.75407 1.000 96.24911  ? 46  PRO   A CG  1 
ATOM   340  C  CD  . PRO   A 1 49  ? -38.14027 -0.09073 -42.12480 1.000 102.26522 ? 46  PRO   A CD  1 
ATOM   341  N  N   . HIS   A 1 50  ? -34.88556 -2.97274 -40.32063 1.000 104.71074 ? 47  HIS   A N   1 
ATOM   342  C  CA  . HIS   A 1 50  ? -34.59547 -4.33683 -39.91271 1.000 109.15891 ? 47  HIS   A CA  1 
ATOM   343  C  C   . HIS   A 1 50  ? -34.67599 -4.46462 -38.39389 1.000 117.86299 ? 47  HIS   A C   1 
ATOM   344  O  O   . HIS   A 1 50  ? -34.72929 -3.47603 -37.65794 1.000 114.67016 ? 47  HIS   A O   1 
ATOM   345  C  CB  . HIS   A 1 50  ? -33.22150 -4.76431 -40.43785 1.000 106.03896 ? 47  HIS   A CB  1 
ATOM   346  C  CG  . HIS   A 1 50  ? -33.18002 -4.95169 -41.92446 1.000 123.19938 ? 47  HIS   A CG  1 
ATOM   347  N  ND1 . HIS   A 1 50  ? -32.04148 -4.74157 -42.67389 1.000 121.82850 ? 47  HIS   A ND1 1 
ATOM   348  C  CD2 . HIS   A 1 50  ? -34.13666 -5.34905 -42.79794 1.000 127.61038 ? 47  HIS   A CD2 1 
ATOM   349  C  CE1 . HIS   A 1 50  ? -32.30254 -4.98946 -43.94585 1.000 124.23537 ? 47  HIS   A CE1 1 
ATOM   350  N  NE2 . HIS   A 1 50  ? -33.56615 -5.36145 -44.04787 1.000 130.34301 ? 47  HIS   A NE2 1 
ATOM   351  N  N   . ASN   A 1 51  ? -34.68090 -5.71502 -37.92728 1.000 121.97084 ? 48  ASN   A N   1 
ATOM   352  C  CA  . ASN   A 1 51  ? -34.83289 -5.96863 -36.49816 1.000 116.30888 ? 48  ASN   A CA  1 
ATOM   353  C  C   . ASN   A 1 51  ? -33.57729 -5.61053 -35.71422 1.000 112.74925 ? 48  ASN   A C   1 
ATOM   354  O  O   . ASN   A 1 51  ? -33.67003 -5.26022 -34.53222 1.000 109.32685 ? 48  ASN   A O   1 
ATOM   355  C  CB  . ASN   A 1 51  ? -35.21597 -7.42805 -36.26614 1.000 114.75240 ? 48  ASN   A CB  1 
ATOM   356  C  CG  . ASN   A 1 51  ? -36.62632 -7.73273 -36.72594 1.000 126.13459 ? 48  ASN   A CG  1 
ATOM   357  O  OD1 . ASN   A 1 51  ? -37.57683 -7.64307 -35.94873 1.000 131.21317 ? 48  ASN   A OD1 1 
ATOM   358  N  ND2 . ASN   A 1 51  ? -36.77218 -8.08314 -37.99893 1.000 117.87783 ? 48  ASN   A ND2 1 
ATOM   359  N  N   . SER   A 1 52  ? -32.40204 -5.68732 -36.34428 1.000 109.95140 ? 49  SER   A N   1 
ATOM   360  C  CA  . SER   A 1 52  ? -31.16648 -5.31362 -35.66518 1.000 111.20253 ? 49  SER   A CA  1 
ATOM   361  C  C   . SER   A 1 52  ? -31.08359 -3.82086 -35.37916 1.000 114.44199 ? 49  SER   A C   1 
ATOM   362  O  O   . SER   A 1 52  ? -30.23693 -3.40512 -34.58037 1.000 107.72988 ? 49  SER   A O   1 
ATOM   363  C  CB  . SER   A 1 52  ? -29.95756 -5.74586 -36.49776 1.000 105.61602 ? 49  SER   A CB  1 
ATOM   364  O  OG  . SER   A 1 52  ? -28.74679 -5.30346 -35.90745 1.000 116.12127 ? 49  SER   A OG  1 
ATOM   365  N  N   . HIS   A 1 53  ? -31.93764 -3.01478 -36.00519 1.000 112.67032 ? 50  HIS   A N   1 
ATOM   366  C  CA  . HIS   A 1 53  ? -31.95653 -1.57212 -35.80886 1.000 105.77772 ? 50  HIS   A CA  1 
ATOM   367  C  C   . HIS   A 1 53  ? -32.67683 -1.14773 -34.53533 1.000 108.27782 ? 50  HIS   A C   1 
ATOM   368  O  O   . HIS   A 1 53  ? -32.79967 0.05708  -34.29077 1.000 105.24004 ? 50  HIS   A O   1 
ATOM   369  C  CB  . HIS   A 1 53  ? -32.61221 -0.89734 -37.01486 1.000 99.98151  ? 50  HIS   A CB  1 
ATOM   370  C  CG  . HIS   A 1 53  ? -31.88239 -1.12409 -38.30085 1.000 96.84817  ? 50  HIS   A CG  1 
ATOM   371  N  ND1 . HIS   A 1 53  ? -32.36229 -0.68590 -39.51587 1.000 95.46550  ? 50  HIS   A ND1 1 
ATOM   372  C  CD2 . HIS   A 1 53  ? -30.70547 -1.74192 -38.56129 1.000 97.27094  ? 50  HIS   A CD2 1 
ATOM   373  C  CE1 . HIS   A 1 53  ? -31.51439 -1.02707 -40.47008 1.000 98.81565  ? 50  HIS   A CE1 1 
ATOM   374  N  NE2 . HIS   A 1 53  ? -30.50021 -1.66838 -39.91752 1.000 97.54342  ? 50  HIS   A NE2 1 
ATOM   375  N  N   . GLU   A 1 54  ? -33.15249 -2.09209 -33.72512 1.000 114.76219 ? 51  GLU   A N   1 
ATOM   376  C  CA  . GLU   A 1 54  ? -33.87645 -1.75244 -32.50471 1.000 112.36982 ? 51  GLU   A CA  1 
ATOM   377  C  C   . GLU   A 1 54  ? -32.93989 -1.07170 -31.51197 1.000 110.87919 ? 51  GLU   A C   1 
ATOM   378  O  O   . GLU   A 1 54  ? -31.96177 -1.67475 -31.05771 1.000 109.71580 ? 51  GLU   A O   1 
ATOM   379  C  CB  . GLU   A 1 54  ? -34.48700 -3.01091 -31.89166 1.000 115.21487 ? 51  GLU   A CB  1 
ATOM   380  C  CG  . GLU   A 1 54  ? -35.06037 -2.81108 -30.49999 1.000 113.08377 ? 51  GLU   A CG  1 
ATOM   381  C  CD  . GLU   A 1 54  ? -36.40008 -2.09921 -30.52672 1.000 120.06050 ? 51  GLU   A CD  1 
ATOM   382  O  OE1 . GLU   A 1 54  ? -37.02954 -2.05209 -31.60444 1.000 116.77297 ? 51  GLU   A OE1 1 
ATOM   383  O  OE2 . GLU   A 1 54  ? -36.82417 -1.58475 -29.47148 1.000 122.01391 ? 51  GLU   A OE2 1 
ATOM   384  N  N   . GLY   A 1 55  ? -33.23702 0.18548  -31.17716 1.000 105.05664 ? 52  GLY   A N   1 
ATOM   385  C  CA  . GLY   A 1 55  ? -32.48047 0.91633  -30.18389 1.000 100.20853 ? 52  GLY   A CA  1 
ATOM   386  C  C   . GLY   A 1 55  ? -31.29684 1.69905  -30.71335 1.000 99.82807  ? 52  GLY   A C   1 
ATOM   387  O  O   . GLY   A 1 55  ? -30.70889 2.48642  -29.95878 1.000 91.02447  ? 52  GLY   A O   1 
ATOM   388  N  N   . LYS   A 1 56  ? -30.92807 1.51390  -31.97795 1.000 104.83831 ? 53  LYS   A N   1 
ATOM   389  C  CA  . LYS   A 1 56  ? -29.77595 2.20158  -32.54016 1.000 96.76469  ? 53  LYS   A CA  1 
ATOM   390  C  C   . LYS   A 1 56  ? -30.10375 3.66859  -32.81705 1.000 93.01108  ? 53  LYS   A C   1 
ATOM   391  O  O   . LYS   A 1 56  ? -31.26699 4.06557  -32.92644 1.000 88.01840  ? 53  LYS   A O   1 
ATOM   392  C  CB  . LYS   A 1 56  ? -29.31891 1.50561  -33.82250 1.000 97.19557  ? 53  LYS   A CB  1 
ATOM   393  C  CG  . LYS   A 1 56  ? -29.33971 -0.01546 -33.73491 1.000 102.60948 ? 53  LYS   A CG  1 
ATOM   394  C  CD  . LYS   A 1 56  ? -27.95654 -0.59912 -33.49687 1.000 101.57579 ? 53  LYS   A CD  1 
ATOM   395  C  CE  . LYS   A 1 56  ? -27.18175 -0.72759 -34.79939 1.000 97.75381  ? 53  LYS   A CE  1 
ATOM   396  N  NZ  . LYS   A 1 56  ? -25.91789 -1.49763 -34.62352 1.000 94.04922  ? 53  LYS   A NZ  1 
ATOM   397  N  N   . THR   A 1 57  ? -29.05293 4.47753  -32.93256 1.000 89.11104  ? 54  THR   A N   1 
ATOM   398  C  CA  . THR   A 1 57  ? -29.18107 5.91478  -33.14130 1.000 81.85705  ? 54  THR   A CA  1 
ATOM   399  C  C   . THR   A 1 57  ? -28.99278 6.24952  -34.61736 1.000 80.11480  ? 54  THR   A C   1 
ATOM   400  O  O   . THR   A 1 57  ? -28.05785 5.75456  -35.25580 1.000 80.59310  ? 54  THR   A O   1 
ATOM   401  C  CB  . THR   A 1 57  ? -28.15689 6.67131  -32.29441 1.000 77.71075  ? 54  THR   A CB  1 
ATOM   402  O  OG1 . THR   A 1 57  ? -28.31096 6.30660  -30.91730 1.000 88.58956  ? 54  THR   A OG1 1 
ATOM   403  C  CG2 . THR   A 1 57  ? -28.34783 8.16811  -32.43709 1.000 72.07246  ? 54  THR   A CG2 1 
ATOM   404  N  N   . PHE   A 1 58  ? -29.87732 7.09137  -35.15302 1.000 73.21331  ? 55  PHE   A N   1 
ATOM   405  C  CA  . PHE   A 1 58  ? -29.84829 7.48497  -36.55593 1.000 69.15848  ? 55  PHE   A CA  1 
ATOM   406  C  C   . PHE   A 1 58  ? -29.70556 8.99466  -36.69038 1.000 64.76725  ? 55  PHE   A C   1 
ATOM   407  O  O   . PHE   A 1 58  ? -30.33486 9.75596  -35.95084 1.000 66.42002  ? 55  PHE   A O   1 
ATOM   408  C  CB  . PHE   A 1 58  ? -31.11734 7.02301  -37.27966 1.000 65.14965  ? 55  PHE   A CB  1 
ATOM   409  C  CG  . PHE   A 1 58  ? -31.20139 5.53726  -37.46587 1.000 74.45410  ? 55  PHE   A CG  1 
ATOM   410  C  CD1 . PHE   A 1 58  ? -31.73216 4.72888  -36.47261 1.000 75.30171  ? 55  PHE   A CD1 1 
ATOM   411  C  CD2 . PHE   A 1 58  ? -30.75017 4.94720  -38.63494 1.000 70.83763  ? 55  PHE   A CD2 1 
ATOM   412  C  CE1 . PHE   A 1 58  ? -31.81020 3.35808  -36.64252 1.000 79.05398  ? 55  PHE   A CE1 1 
ATOM   413  C  CE2 . PHE   A 1 58  ? -30.82536 3.57726  -38.81166 1.000 78.65278  ? 55  PHE   A CE2 1 
ATOM   414  C  CZ  . PHE   A 1 58  ? -31.35670 2.78101  -37.81344 1.000 81.29451  ? 55  PHE   A CZ  1 
ATOM   415  N  N   . TYR   A 1 59  ? -28.87773 9.42467  -37.63960 1.000 61.69190  ? 56  TYR   A N   1 
ATOM   416  C  CA  . TYR   A 1 59  ? -28.79313 10.83056 -38.01667 1.000 60.67185  ? 56  TYR   A CA  1 
ATOM   417  C  C   . TYR   A 1 59  ? -29.86005 11.13784 -39.06146 1.000 64.99139  ? 56  TYR   A C   1 
ATOM   418  O  O   . TYR   A 1 59  ? -30.05215 10.36584 -40.00617 1.000 69.42467  ? 56  TYR   A O   1 
ATOM   419  C  CB  . TYR   A 1 59  ? -27.40771 11.16584 -38.56504 1.000 61.43148  ? 56  TYR   A CB  1 
ATOM   420  C  CG  . TYR   A 1 59  ? -26.33061 11.35758 -37.51967 1.000 63.22210  ? 56  TYR   A CG  1 
ATOM   421  C  CD1 . TYR   A 1 59  ? -25.80797 10.27480 -36.82300 1.000 61.14304  ? 56  TYR   A CD1 1 
ATOM   422  C  CD2 . TYR   A 1 59  ? -25.81284 12.61864 -37.25583 1.000 59.70237  ? 56  TYR   A CD2 1 
ATOM   423  C  CE1 . TYR   A 1 59  ? -24.81288 10.44741 -35.88038 1.000 62.87118  ? 56  TYR   A CE1 1 
ATOM   424  C  CE2 . TYR   A 1 59  ? -24.81919 12.80075 -36.31653 1.000 62.65765  ? 56  TYR   A CE2 1 
ATOM   425  C  CZ  . TYR   A 1 59  ? -24.32256 11.71251 -35.63197 1.000 68.42893  ? 56  TYR   A CZ  1 
ATOM   426  O  OH  . TYR   A 1 59  ? -23.32940 11.89027 -34.69792 1.000 73.06817  ? 56  TYR   A OH  1 
ATOM   427  N  N   . VAL   A 1 60  ? -30.55978 12.25701 -38.88735 1.000 57.89208  ? 57  VAL   A N   1 
ATOM   428  C  CA  . VAL   A 1 60  ? -31.59921 12.67701 -39.81755 1.000 56.92678  ? 57  VAL   A CA  1 
ATOM   429  C  C   . VAL   A 1 60  ? -31.39640 14.14235 -40.16736 1.000 56.04769  ? 57  VAL   A C   1 
ATOM   430  O  O   . VAL   A 1 60  ? -30.90800 14.93363 -39.35588 1.000 65.67412  ? 57  VAL   A O   1 
ATOM   431  C  CB  . VAL   A 1 60  ? -33.02106 12.45149 -39.25366 1.000 61.51077  ? 57  VAL   A CB  1 
ATOM   432  C  CG1 . VAL   A 1 60  ? -33.24620 10.98082 -38.94551 1.000 63.59462  ? 57  VAL   A CG1 1 
ATOM   433  C  CG2 . VAL   A 1 60  ? -33.25097 13.30816 -38.01632 1.000 58.30205  ? 57  VAL   A CG2 1 
ATOM   434  N  N   . LEU   A 1 61  ? -31.77284 14.49865 -41.38866 1.000 60.61248  ? 58  LEU   A N   1 
ATOM   435  C  CA  . LEU   A 1 61  ? -31.73943 15.89430 -41.79386 1.000 63.08962  ? 58  LEU   A CA  1 
ATOM   436  C  C   . LEU   A 1 61  ? -32.72437 16.69640 -40.94586 1.000 66.34379  ? 58  LEU   A C   1 
ATOM   437  O  O   . LEU   A 1 61  ? -33.83629 16.22735 -40.67686 1.000 78.82042  ? 58  LEU   A O   1 
ATOM   438  C  CB  . LEU   A 1 61  ? -32.08749 16.02315 -43.28041 1.000 65.66402  ? 58  LEU   A CB  1 
ATOM   439  C  CG  . LEU   A 1 61  ? -31.90923 17.36423 -44.00502 1.000 79.31378  ? 58  LEU   A CG  1 
ATOM   440  C  CD1 . LEU   A 1 61  ? -31.59386 17.13241 -45.47415 1.000 62.58642  ? 58  LEU   A CD1 1 
ATOM   441  C  CD2 . LEU   A 1 61  ? -33.14340 18.25302 -43.87063 1.000 71.67892  ? 58  LEU   A CD2 1 
ATOM   442  N  N   . PRO   A 1 62  ? -32.34703 17.89391 -40.48800 1.000 70.15563  ? 59  PRO   A N   1 
ATOM   443  C  CA  . PRO   A 1 62  ? -33.25620 18.67326 -39.63434 1.000 68.53997  ? 59  PRO   A CA  1 
ATOM   444  C  C   . PRO   A 1 62  ? -34.54007 19.05173 -40.35794 1.000 71.27343  ? 59  PRO   A C   1 
ATOM   445  O  O   . PRO   A 1 62  ? -34.52457 19.89004 -41.26452 1.000 76.41635  ? 59  PRO   A O   1 
ATOM   446  C  CB  . PRO   A 1 62  ? -32.42831 19.91503 -39.27841 1.000 68.50694  ? 59  PRO   A CB  1 
ATOM   447  C  CG  . PRO   A 1 62  ? -31.00298 19.50891 -39.50837 1.000 65.37402  ? 59  PRO   A CG  1 
ATOM   448  C  CD  . PRO   A 1 62  ? -31.03985 18.55083 -40.65429 1.000 62.72819  ? 59  PRO   A CD  1 
ATOM   449  N  N   . ASN   A 1 63  ? -35.66204 18.45328 -39.95386 1.000 76.40238  ? 60  ASN   A N   1 
ATOM   450  C  CA  . ASN   A 1 63  ? -36.94415 18.69633 -40.59866 1.000 75.31820  ? 60  ASN   A CA  1 
ATOM   451  C  C   . ASN   A 1 63  ? -37.91416 19.52669 -39.76582 1.000 78.33137  ? 60  ASN   A C   1 
ATOM   452  O  O   . ASN   A 1 63  ? -38.97576 19.89664 -40.27781 1.000 86.31566  ? 60  ASN   A O   1 
ATOM   453  C  CB  . ASN   A 1 63  ? -37.60133 17.35688 -40.97316 1.000 74.16115  ? 60  ASN   A CB  1 
ATOM   454  C  CG  . ASN   A 1 63  ? -37.71228 16.40537 -39.79247 1.000 84.47034  ? 60  ASN   A CG  1 
ATOM   455  O  OD1 . ASN   A 1 63  ? -37.92828 16.82353 -38.65380 1.000 86.36039  ? 60  ASN   A OD1 1 
ATOM   456  N  ND2 . ASN   A 1 63  ? -37.54390 15.11524 -40.05993 1.000 82.62255  ? 60  ASN   A ND2 1 
ATOM   457  N  N   . ASP   A 1 64  ? -37.58941 19.82985 -38.50991 1.000 79.42335  ? 61  ASP   A N   1 
ATOM   458  C  CA  . ASP   A 1 64  ? -38.40947 20.70680 -37.68507 1.000 77.23741  ? 61  ASP   A CA  1 
ATOM   459  C  C   . ASP   A 1 64  ? -37.49044 21.68465 -36.96001 1.000 74.78484  ? 61  ASP   A C   1 
ATOM   460  O  O   . ASP   A 1 64  ? -36.26341 21.62091 -37.07918 1.000 76.61043  ? 61  ASP   A O   1 
ATOM   461  C  CB  . ASP   A 1 64  ? -39.29297 19.90562 -36.71644 1.000 76.13465  ? 61  ASP   A CB  1 
ATOM   462  C  CG  . ASP   A 1 64  ? -38.49681 18.97751 -35.81914 1.000 85.90248  ? 61  ASP   A CG  1 
ATOM   463  O  OD1 . ASP   A 1 64  ? -37.25614 19.08432 -35.79727 1.000 88.38888  ? 61  ASP   A OD1 1 
ATOM   464  O  OD2 . ASP   A 1 64  ? -39.11604 18.13878 -35.12818 1.000 95.13790  ? 61  ASP   A OD2 1 
ATOM   465  N  N   . ASP   A 1 65  ? -38.08704 22.59017 -36.18444 1.000 70.73272  ? 62  ASP   A N   1 
ATOM   466  C  CA  . ASP   A 1 65  ? -37.30132 23.67102 -35.60114 1.000 71.01808  ? 62  ASP   A CA  1 
ATOM   467  C  C   . ASP   A 1 65  ? -36.39786 23.18128 -34.47548 1.000 67.82097  ? 62  ASP   A C   1 
ATOM   468  O  O   . ASP   A 1 65  ? -35.30107 23.71923 -34.28642 1.000 63.30941  ? 62  ASP   A O   1 
ATOM   469  C  CB  . ASP   A 1 65  ? -38.22468 24.77421 -35.09557 1.000 71.57287  ? 62  ASP   A CB  1 
ATOM   470  C  CG  . ASP   A 1 65  ? -37.54073 26.11401 -35.04786 1.000 65.28559  ? 62  ASP   A CG  1 
ATOM   471  O  OD1 . ASP   A 1 65  ? -37.33220 26.69955 -36.13077 1.000 63.25990  ? 62  ASP   A OD1 1 
ATOM   472  O  OD2 . ASP   A 1 65  ? -37.19649 26.56695 -33.93711 1.000 63.68224  ? 62  ASP   A OD2 1 
ATOM   473  N  N   . THR   A 1 66  ? -36.83462 22.17954 -33.71318 1.000 69.55540  ? 63  THR   A N   1 
ATOM   474  C  CA  . THR   A 1 66  ? -35.98765 21.65846 -32.64709 1.000 64.98831  ? 63  THR   A CA  1 
ATOM   475  C  C   . THR   A 1 66  ? -34.68790 21.09283 -33.20474 1.000 67.78287  ? 63  THR   A C   1 
ATOM   476  O  O   . THR   A 1 66  ? -33.60781 21.33732 -32.65415 1.000 66.57055  ? 63  THR   A O   1 
ATOM   477  C  CB  . THR   A 1 66  ? -36.74288 20.60030 -31.84911 1.000 69.54020  ? 63  THR   A CB  1 
ATOM   478  O  OG1 . THR   A 1 66  ? -37.90289 21.19870 -31.26075 1.000 70.33030  ? 63  THR   A OG1 1 
ATOM   479  C  CG2 . THR   A 1 66  ? -35.85730 20.03242 -30.75086 1.000 67.59897  ? 63  THR   A CG2 1 
ATOM   480  N  N   . LEU   A 1 67  ? -34.76990 20.34776 -34.30931 1.000 69.95778  ? 64  LEU   A N   1 
ATOM   481  C  CA  . LEU   A 1 67  ? -33.56581 19.78702 -34.91068 1.000 66.28609  ? 64  LEU   A CA  1 
ATOM   482  C  C   . LEU   A 1 67  ? -32.73724 20.85528 -35.61309 1.000 68.81402  ? 64  LEU   A C   1 
ATOM   483  O  O   . LEU   A 1 67  ? -31.50953 20.73616 -35.68068 1.000 64.93265  ? 64  LEU   A O   1 
ATOM   484  C  CB  . LEU   A 1 67  ? -33.93591 18.67405 -35.89134 1.000 67.88561  ? 64  LEU   A CB  1 
ATOM   485  C  CG  . LEU   A 1 67  ? -34.59033 17.42804 -35.29192 1.000 69.91065  ? 64  LEU   A CG  1 
ATOM   486  C  CD1 . LEU   A 1 67  ? -34.88443 16.39883 -36.37752 1.000 63.84588  ? 64  LEU   A CD1 1 
ATOM   487  C  CD2 . LEU   A 1 67  ? -33.71985 16.83495 -34.19064 1.000 70.41052  ? 64  LEU   A CD2 1 
ATOM   488  N  N   . ARG   A 1 68  ? -33.38070 21.90009 -36.13761 1.000 63.71557  ? 65  ARG   A N   1 
ATOM   489  C  CA  . ARG   A 1 68  ? -32.62585 22.98796 -36.74977 1.000 59.97225  ? 65  ARG   A CA  1 
ATOM   490  C  C   . ARG   A 1 68  ? -31.78356 23.72518 -35.71388 1.000 64.29465  ? 65  ARG   A C   1 
ATOM   491  O  O   . ARG   A 1 68  ? -30.60766 24.02145 -35.95978 1.000 68.13379  ? 65  ARG   A O   1 
ATOM   492  C  CB  . ARG   A 1 68  ? -33.57272 23.95509 -37.46104 1.000 58.65943  ? 65  ARG   A CB  1 
ATOM   493  C  CG  . ARG   A 1 68  ? -34.11195 23.42992 -38.78218 1.000 59.22661  ? 65  ARG   A CG  1 
ATOM   494  C  CD  . ARG   A 1 68  ? -34.75456 24.53884 -39.60422 1.000 67.11405  ? 65  ARG   A CD  1 
ATOM   495  N  NE  . ARG   A 1 68  ? -35.85776 25.19162 -38.90726 1.000 82.27635  ? 65  ARG   A NE  1 
ATOM   496  C  CZ  . ARG   A 1 68  ? -37.12755 24.81704 -38.99089 1.000 76.68793  ? 65  ARG   A CZ  1 
ATOM   497  N  NH1 . ARG   A 1 68  ? -37.49717 23.78529 -39.73285 1.000 70.92265  ? 65  ARG   A NH1 1 
ATOM   498  N  NH2 . ARG   A 1 68  ? -38.05033 25.49852 -38.31726 1.000 79.65576  ? 65  ARG   A NH2 1 
ATOM   499  N  N   . VAL   A 1 69  ? -32.36133 24.02255 -34.54883 1.000 60.64848  ? 66  VAL   A N   1 
ATOM   500  C  CA  . VAL   A 1 69  ? -31.60930 24.70000 -33.49543 1.000 57.05703  ? 66  VAL   A CA  1 
ATOM   501  C  C   . VAL   A 1 69  ? -30.47561 23.81092 -33.00201 1.000 57.90498  ? 66  VAL   A C   1 
ATOM   502  O  O   . VAL   A 1 69  ? -29.33494 24.25972 -32.83878 1.000 63.53234  ? 66  VAL   A O   1 
ATOM   503  C  CB  . VAL   A 1 69  ? -32.54635 25.11200 -32.34681 1.000 60.29646  ? 66  VAL   A CB  1 
ATOM   504  C  CG1 . VAL   A 1 69  ? -31.73855 25.59055 -31.15688 1.000 47.61674  ? 66  VAL   A CG1 1 
ATOM   505  C  CG2 . VAL   A 1 69  ? -33.50565 26.19387 -32.80625 1.000 57.27621  ? 66  VAL   A CG2 1 
ATOM   506  N  N   . GLU   A 1 70  ? -30.77824 22.53774 -32.74231 1.000 54.43870  ? 67  GLU   A N   1 
ATOM   507  C  CA  . GLU   A 1 70  ? -29.74991 21.61114 -32.28306 1.000 58.96117  ? 67  GLU   A CA  1 
ATOM   508  C  C   . GLU   A 1 70  ? -28.64133 21.45833 -33.31795 1.000 59.87772  ? 67  GLU   A C   1 
ATOM   509  O  O   . GLU   A 1 70  ? -27.46210 21.34247 -32.96338 1.000 57.54058  ? 67  GLU   A O   1 
ATOM   510  C  CB  . GLU   A 1 70  ? -30.38018 20.25601 -31.96099 1.000 61.25255  ? 67  GLU   A CB  1 
ATOM   511  C  CG  . GLU   A 1 70  ? -31.26560 20.26413 -30.72045 1.000 70.23471  ? 67  GLU   A CG  1 
ATOM   512  C  CD  . GLU   A 1 70  ? -31.98237 18.94472 -30.50744 1.000 78.31111  ? 67  GLU   A CD  1 
ATOM   513  O  OE1 . GLU   A 1 70  ? -31.90696 18.08122 -31.40610 1.000 79.80679  ? 67  GLU   A OE1 1 
ATOM   514  O  OE2 . GLU   A 1 70  ? -32.61508 18.76825 -29.44241 1.000 78.06394  ? 67  GLU   A OE2 1 
ATOM   515  N  N   . ALA   A 1 71  ? -28.99880 21.47338 -34.60520 1.000 62.65528  ? 68  ALA   A N   1 
ATOM   516  C  CA  . ALA   A 1 71  ? -27.99456 21.31787 -35.65268 1.000 54.55140  ? 68  ALA   A CA  1 
ATOM   517  C  C   . ALA   A 1 71  ? -27.04433 22.50615 -35.69532 1.000 50.73137  ? 68  ALA   A C   1 
ATOM   518  O  O   . ALA   A 1 71  ? -25.83524 22.33094 -35.88390 1.000 50.90348  ? 68  ALA   A O   1 
ATOM   519  C  CB  . ALA   A 1 71  ? -28.66560 21.12517 -37.01052 1.000 50.54346  ? 68  ALA   A CB  1 
ATOM   520  N  N   . PHE   A 1 72  ? -27.56678 23.72430 -35.54118 1.000 47.79806  ? 69  PHE   A N   1 
ATOM   521  C  CA  . PHE   A 1 72  ? -26.68848 24.88883 -35.55188 1.000 52.35998  ? 69  PHE   A CA  1 
ATOM   522  C  C   . PHE   A 1 72  ? -25.79842 24.90886 -34.31856 1.000 54.78075  ? 69  PHE   A C   1 
ATOM   523  O  O   . PHE   A 1 72  ? -24.59506 25.16691 -34.41076 1.000 59.30028  ? 69  PHE   A O   1 
ATOM   524  C  CB  . PHE   A 1 72  ? -27.49298 26.18241 -35.62978 1.000 48.14040  ? 69  PHE   A CB  1 
ATOM   525  C  CG  . PHE   A 1 72  ? -26.64380 27.41884 -35.52088 1.000 54.13173  ? 69  PHE   A CG  1 
ATOM   526  C  CD1 . PHE   A 1 72  ? -26.04908 27.96125 -36.64965 1.000 54.10193  ? 69  PHE   A CD1 1 
ATOM   527  C  CD2 . PHE   A 1 72  ? -26.40433 28.01587 -34.29242 1.000 55.41003  ? 69  PHE   A CD2 1 
ATOM   528  C  CE1 . PHE   A 1 72  ? -25.25861 29.09294 -36.55966 1.000 53.02758  ? 69  PHE   A CE1 1 
ATOM   529  C  CE2 . PHE   A 1 72  ? -25.61230 29.14583 -34.19403 1.000 53.11624  ? 69  PHE   A CE2 1 
ATOM   530  C  CZ  . PHE   A 1 72  ? -25.03878 29.68486 -35.32995 1.000 56.31010  ? 69  PHE   A CZ  1 
ATOM   531  N  N   . GLU   A 1 73  ? -26.37845 24.66510 -33.14607 1.000 57.04006  ? 70  GLU   A N   1 
ATOM   532  C  CA  . GLU   A 1 73  ? -25.58844 24.70887 -31.92505 1.000 55.52235  ? 70  GLU   A CA  1 
ATOM   533  C  C   . GLU   A 1 73  ? -24.44051 23.70900 -31.96149 1.000 55.83306  ? 70  GLU   A C   1 
ATOM   534  O  O   . GLU   A 1 73  ? -23.43207 23.90995 -31.27733 1.000 60.45100  ? 70  GLU   A O   1 
ATOM   535  C  CB  . GLU   A 1 73  ? -26.49231 24.46109 -30.72078 1.000 57.04174  ? 70  GLU   A CB  1 
ATOM   536  C  CG  . GLU   A 1 73  ? -27.24719 25.70388 -30.27266 1.000 58.10295  ? 70  GLU   A CG  1 
ATOM   537  C  CD  . GLU   A 1 73  ? -28.43736 25.38445 -29.38892 1.000 81.76712  ? 70  GLU   A CD  1 
ATOM   538  O  OE1 . GLU   A 1 73  ? -28.57778 24.21755 -28.95900 1.000 81.43183  ? 70  GLU   A OE1 1 
ATOM   539  O  OE2 . GLU   A 1 73  ? -29.23560 26.30839 -29.12567 1.000 84.01291  ? 70  GLU   A OE2 1 
ATOM   540  N  N   . TYR   A 1 74  ? -24.55857 22.64935 -32.76182 1.000 51.44924  ? 71  TYR   A N   1 
ATOM   541  C  CA  . TYR   A 1 74  ? -23.49036 21.66613 -32.88352 1.000 49.46698  ? 71  TYR   A CA  1 
ATOM   542  C  C   . TYR   A 1 74  ? -22.54022 21.96420 -34.03872 1.000 58.45046  ? 71  TYR   A C   1 
ATOM   543  O  O   . TYR   A 1 74  ? -21.32060 21.85177 -33.87268 1.000 53.68003  ? 71  TYR   A O   1 
ATOM   544  C  CB  . TYR   A 1 74  ? -24.08743 20.27035 -33.05174 1.000 48.71647  ? 71  TYR   A CB  1 
ATOM   545  C  CG  . TYR   A 1 74  ? -23.11309 19.15074 -32.78039 1.000 57.92702  ? 71  TYR   A CG  1 
ATOM   546  C  CD1 . TYR   A 1 74  ? -22.44122 19.06653 -31.56879 1.000 59.36979  ? 71  TYR   A CD1 1 
ATOM   547  C  CD2 . TYR   A 1 74  ? -22.87400 18.16885 -33.73272 1.000 56.95769  ? 71  TYR   A CD2 1 
ATOM   548  C  CE1 . TYR   A 1 74  ? -21.55183 18.04014 -31.31530 1.000 62.48812  ? 71  TYR   A CE1 1 
ATOM   549  C  CE2 . TYR   A 1 74  ? -21.98995 17.13539 -33.48756 1.000 57.29908  ? 71  TYR   A CE2 1 
ATOM   550  C  CZ  . TYR   A 1 74  ? -21.32966 17.07787 -32.27680 1.000 66.01579  ? 71  TYR   A CZ  1 
ATOM   551  O  OH  . TYR   A 1 74  ? -20.44330 16.05724 -32.01617 1.000 78.85175  ? 71  TYR   A OH  1 
ATOM   552  N  N   . TYR   A 1 75  ? -23.06848 22.34397 -35.20762 1.000 51.42531  ? 72  TYR   A N   1 
ATOM   553  C  CA  . TYR   A 1 75  ? -22.24694 22.54566 -36.39472 1.000 49.17830  ? 72  TYR   A CA  1 
ATOM   554  C  C   . TYR   A 1 75  ? -22.04781 24.00659 -36.77407 1.000 48.95166  ? 72  TYR   A C   1 
ATOM   555  O  O   . TYR   A 1 75  ? -21.17162 24.29496 -37.59686 1.000 47.86163  ? 72  TYR   A O   1 
ATOM   556  C  CB  . TYR   A 1 75  ? -22.85239 21.81105 -37.59986 1.000 47.52544  ? 72  TYR   A CB  1 
ATOM   557  C  CG  . TYR   A 1 75  ? -23.11121 20.34094 -37.37394 1.000 49.71099  ? 72  TYR   A CG  1 
ATOM   558  C  CD1 . TYR   A 1 75  ? -22.07235 19.42201 -37.39893 1.000 46.41838  ? 72  TYR   A CD1 1 
ATOM   559  C  CD2 . TYR   A 1 75  ? -24.39932 19.86806 -37.16111 1.000 48.10068  ? 72  TYR   A CD2 1 
ATOM   560  C  CE1 . TYR   A 1 75  ? -22.30674 18.07332 -37.19816 1.000 51.70049  ? 72  TYR   A CE1 1 
ATOM   561  C  CE2 . TYR   A 1 75  ? -24.64426 18.52349 -36.96213 1.000 48.89024  ? 72  TYR   A CE2 1 
ATOM   562  C  CZ  . TYR   A 1 75  ? -23.59594 17.62964 -36.98166 1.000 56.75787  ? 72  TYR   A CZ  1 
ATOM   563  O  OH  . TYR   A 1 75  ? -23.83863 16.28880 -36.78258 1.000 68.28489  ? 72  TYR   A OH  1 
ATOM   564  N  N   . HIS   A 1 76  ? -22.83162 24.92615 -36.20958 1.000 51.80964  ? 73  HIS   A N   1 
ATOM   565  C  CA  . HIS   A 1 76  ? -22.74764 26.35595 -36.52637 1.000 53.90984  ? 73  HIS   A CA  1 
ATOM   566  C  C   . HIS   A 1 76  ? -22.99428 26.61923 -38.00954 1.000 57.61716  ? 73  HIS   A C   1 
ATOM   567  O  O   . HIS   A 1 76  ? -22.36936 27.48874 -38.61977 1.000 62.71493  ? 73  HIS   A O   1 
ATOM   568  C  CB  . HIS   A 1 76  ? -21.41293 26.94941 -36.07327 1.000 52.14368  ? 73  HIS   A CB  1 
ATOM   569  C  CG  . HIS   A 1 76  ? -21.29735 27.08490 -34.58756 1.000 59.02851  ? 73  HIS   A CG  1 
ATOM   570  N  ND1 . HIS   A 1 76  ? -20.52148 28.04911 -33.98348 1.000 52.92936  ? 73  HIS   A ND1 1 
ATOM   571  C  CD2 . HIS   A 1 76  ? -21.86864 26.37894 -33.58333 1.000 57.33679  ? 73  HIS   A CD2 1 
ATOM   572  C  CE1 . HIS   A 1 76  ? -20.61494 27.92956 -32.67126 1.000 59.21854  ? 73  HIS   A CE1 1 
ATOM   573  N  NE2 . HIS   A 1 76  ? -21.42586 26.92272 -32.40222 1.000 64.46371  ? 73  HIS   A NE2 1 
ATOM   574  N  N   . THR   A 1 77  ? -23.91979 25.86163 -38.59318 1.000 55.29553  ? 74  THR   A N   1 
ATOM   575  C  CA  . THR   A 1 77  ? -24.36078 26.09272 -39.95975 1.000 60.46935  ? 74  THR   A CA  1 
ATOM   576  C  C   . THR   A 1 77  ? -25.84408 25.77058 -40.06811 1.000 61.38839  ? 74  THR   A C   1 
ATOM   577  O  O   . THR   A 1 77  ? -26.34930 24.86549 -39.40000 1.000 59.01167  ? 74  THR   A O   1 
ATOM   578  C  CB  . THR   A 1 77  ? -23.55870 25.25906 -40.97219 1.000 58.51876  ? 74  THR   A CB  1 
ATOM   579  O  OG1 . THR   A 1 77  ? -23.97055 25.59367 -42.30389 1.000 69.24699  ? 74  THR   A OG1 1 
ATOM   580  C  CG2 . THR   A 1 77  ? -23.77059 23.77204 -40.73684 1.000 58.25439  ? 74  THR   A CG2 1 
ATOM   581  N  N   . THR   A 1 78  ? -26.53792 26.52862 -40.91741 1.000 58.13325  ? 75  THR   A N   1 
ATOM   582  C  CA  . THR   A 1 78  ? -27.94153 26.28494 -41.21687 1.000 55.89776  ? 75  THR   A CA  1 
ATOM   583  C  C   . THR   A 1 78  ? -28.15026 25.68943 -42.60078 1.000 61.08735  ? 75  THR   A C   1 
ATOM   584  O  O   . THR   A 1 78  ? -29.30057 25.48422 -43.00462 1.000 69.22432  ? 75  THR   A O   1 
ATOM   585  C  CB  . THR   A 1 78  ? -28.75410 27.58112 -41.08173 1.000 55.82334  ? 75  THR   A CB  1 
ATOM   586  O  OG1 . THR   A 1 78  ? -28.12932 28.62911 -41.83199 1.000 55.98778  ? 75  THR   A OG1 1 
ATOM   587  C  CG2 . THR   A 1 78  ? -28.84200 27.99953 -39.62382 1.000 62.29522  ? 75  THR   A CG2 1 
ATOM   588  N  N   . ASP   A 1 79  ? -27.07656 25.42518 -43.33563 1.000 60.37321  ? 76  ASP   A N   1 
ATOM   589  C  CA  . ASP   A 1 79  ? -27.16073 24.77878 -44.63568 1.000 55.12668  ? 76  ASP   A CA  1 
ATOM   590  C  C   . ASP   A 1 79  ? -27.84150 23.42290 -44.47719 1.000 58.91045  ? 76  ASP   A C   1 
ATOM   591  O  O   . ASP   A 1 79  ? -27.31323 22.55151 -43.76866 1.000 60.54221  ? 76  ASP   A O   1 
ATOM   592  C  CB  . ASP   A 1 79  ? -25.75240 24.62748 -45.22017 1.000 62.45006  ? 76  ASP   A CB  1 
ATOM   593  C  CG  . ASP   A 1 79  ? -25.71604 23.81668 -46.51050 1.000 68.52115  ? 76  ASP   A CG  1 
ATOM   594  O  OD1 . ASP   A 1 79  ? -26.77936 23.54495 -47.10797 1.000 70.56436  ? 76  ASP   A OD1 1 
ATOM   595  O  OD2 . ASP   A 1 79  ? -24.59712 23.45622 -46.93545 1.000 63.47540  ? 76  ASP   A OD2 1 
ATOM   596  N  N   . PRO   A 1 80  ? -28.99647 23.19982 -45.10801 1.000 63.96101  ? 77  PRO   A N   1 
ATOM   597  C  CA  . PRO   A 1 80  ? -29.71684 21.93428 -44.88773 1.000 69.92500  ? 77  PRO   A CA  1 
ATOM   598  C  C   . PRO   A 1 80  ? -28.94990 20.71036 -45.35209 1.000 68.23334  ? 77  PRO   A C   1 
ATOM   599  O  O   . PRO   A 1 80  ? -29.16438 19.61335 -44.82140 1.000 66.19450  ? 77  PRO   A O   1 
ATOM   600  C  CB  . PRO   A 1 80  ? -31.01271 22.12644 -45.69041 1.000 67.49523  ? 77  PRO   A CB  1 
ATOM   601  C  CG  . PRO   A 1 80  ? -31.13495 23.61156 -45.88603 1.000 64.28398  ? 77  PRO   A CG  1 
ATOM   602  C  CD  . PRO   A 1 80  ? -29.73560 24.11602 -45.99020 1.000 60.96585  ? 77  PRO   A CD  1 
ATOM   603  N  N   . SER   A 1 81  ? -28.05452 20.86400 -46.32094 1.000 56.34655  ? 78  SER   A N   1 
ATOM   604  C  CA  . SER   A 1 81  ? -27.33375 19.73441 -46.88443 1.000 57.26271  ? 78  SER   A CA  1 
ATOM   605  C  C   . SER   A 1 81  ? -26.08810 19.35398 -46.09842 1.000 61.71693  ? 78  SER   A C   1 
ATOM   606  O  O   . SER   A 1 81  ? -25.47885 18.32512 -46.40941 1.000 60.08689  ? 78  SER   A O   1 
ATOM   607  C  CB  . SER   A 1 81  ? -26.92655 20.04586 -48.32266 1.000 57.39131  ? 78  SER   A CB  1 
ATOM   608  O  OG  . SER   A 1 81  ? -25.95637 21.07638 -48.33519 1.000 51.45229  ? 78  SER   A OG  1 
ATOM   609  N  N   . PHE   A 1 82  ? -25.69067 20.15589 -45.10480 1.000 64.44379  ? 79  PHE   A N   1 
ATOM   610  C  CA  . PHE   A 1 82  ? -24.42103 19.92076 -44.42084 1.000 56.29985  ? 79  PHE   A CA  1 
ATOM   611  C  C   . PHE   A 1 82  ? -24.35945 18.52618 -43.81293 1.000 57.84864  ? 79  PHE   A C   1 
ATOM   612  O  O   . PHE   A 1 82  ? -23.39163 17.78558 -44.02928 1.000 55.88157  ? 79  PHE   A O   1 
ATOM   613  C  CB  . PHE   A 1 82  ? -24.18805 20.97874 -43.34261 1.000 45.34916  ? 79  PHE   A CB  1 
ATOM   614  C  CG  . PHE   A 1 82  ? -22.86058 20.84073 -42.65392 1.000 59.14579  ? 79  PHE   A CG  1 
ATOM   615  C  CD1 . PHE   A 1 82  ? -21.72182 21.42324 -43.19133 1.000 58.40230  ? 79  PHE   A CD1 1 
ATOM   616  C  CD2 . PHE   A 1 82  ? -22.74578 20.11355 -41.47662 1.000 55.87700  ? 79  PHE   A CD2 1 
ATOM   617  C  CE1 . PHE   A 1 82  ? -20.49227 21.28934 -42.56631 1.000 54.05806  ? 79  PHE   A CE1 1 
ATOM   618  C  CE2 . PHE   A 1 82  ? -21.52151 19.97334 -40.84638 1.000 52.73944  ? 79  PHE   A CE2 1 
ATOM   619  C  CZ  . PHE   A 1 82  ? -20.39210 20.56354 -41.39233 1.000 55.66273  ? 79  PHE   A CZ  1 
ATOM   620  N  N   . LEU   A 1 83  ? -25.38593 18.15093 -43.04999 1.000 56.05261  ? 80  LEU   A N   1 
ATOM   621  C  CA  . LEU   A 1 83  ? -25.37473 16.85068 -42.39057 1.000 56.94611  ? 80  LEU   A CA  1 
ATOM   622  C  C   . LEU   A 1 83  ? -25.21336 15.71654 -43.39721 1.000 57.37313  ? 80  LEU   A C   1 
ATOM   623  O  O   . LEU   A 1 83  ? -24.49026 14.74677 -43.13895 1.000 56.45375  ? 80  LEU   A O   1 
ATOM   624  C  CB  . LEU   A 1 83  ? -26.65272 16.67576 -41.57049 1.000 60.29328  ? 80  LEU   A CB  1 
ATOM   625  C  CG  . LEU   A 1 83  ? -26.66078 15.48031 -40.62068 1.000 63.70433  ? 80  LEU   A CG  1 
ATOM   626  C  CD1 . LEU   A 1 83  ? -25.38117 15.44172 -39.80639 1.000 71.56398  ? 80  LEU   A CD1 1 
ATOM   627  C  CD2 . LEU   A 1 83  ? -27.85984 15.54829 -39.70421 1.000 71.07693  ? 80  LEU   A CD2 1 
ATOM   628  N  N   . GLY   A 1 84  ? -25.85810 15.83133 -44.55796 1.000 55.15451  ? 81  GLY   A N   1 
ATOM   629  C  CA  . GLY   A 1 84  ? -25.73890 14.78846 -45.56450 1.000 47.74258  ? 81  GLY   A CA  1 
ATOM   630  C  C   . GLY   A 1 84  ? -24.33254 14.67269 -46.12433 1.000 53.16321  ? 81  GLY   A C   1 
ATOM   631  O  O   . GLY   A 1 84  ? -23.78889 13.57013 -46.24991 1.000 49.46385  ? 81  GLY   A O   1 
ATOM   632  N  N   . ARG   A 1 85  ? -23.73019 15.80810 -46.48821 1.000 51.65945  ? 82  ARG   A N   1 
ATOM   633  C  CA  . ARG   A 1 85  ? -22.35366 15.78565 -46.97413 1.000 55.22565  ? 82  ARG   A CA  1 
ATOM   634  C  C   . ARG   A 1 85  ? -21.39933 15.28558 -45.89677 1.000 56.33859  ? 82  ARG   A C   1 
ATOM   635  O  O   . ARG   A 1 85  ? -20.42620 14.58346 -46.19808 1.000 55.14974  ? 82  ARG   A O   1 
ATOM   636  C  CB  . ARG   A 1 85  ? -21.94309 17.17454 -47.46383 1.000 54.41098  ? 82  ARG   A CB  1 
ATOM   637  C  CG  . ARG   A 1 85  ? -22.98563 17.85306 -48.33650 1.000 54.31476  ? 82  ARG   A CG  1 
ATOM   638  C  CD  . ARG   A 1 85  ? -22.37541 18.99677 -49.12545 1.000 57.06240  ? 82  ARG   A CD  1 
ATOM   639  N  NE  . ARG   A 1 85  ? -21.62978 19.91711 -48.27527 1.000 62.75969  ? 82  ARG   A NE  1 
ATOM   640  C  CZ  . ARG   A 1 85  ? -22.14566 21.00573 -47.72211 1.000 65.74478  ? 82  ARG   A CZ  1 
ATOM   641  N  NH1 . ARG   A 1 85  ? -23.41717 21.32975 -47.89074 1.000 72.67900  ? 82  ARG   A NH1 1 
ATOM   642  N  NH2 . ARG   A 1 85  ? -21.36642 21.79021 -46.98291 1.000 64.58847  ? 82  ARG   A NH2 1 
ATOM   643  N  N   . TYR   A 1 86  ? -21.66205 15.63889 -44.63569 1.000 55.83511  ? 83  TYR   A N   1 
ATOM   644  C  CA  . TYR   A 1 86  ? -20.86936 15.10715 -43.53018 1.000 52.24554  ? 83  TYR   A CA  1 
ATOM   645  C  C   . TYR   A 1 86  ? -20.99871 13.59112 -43.45421 1.000 53.23000  ? 83  TYR   A C   1 
ATOM   646  O  O   . TYR   A 1 86  ? -19.99301 12.87143 -43.44039 1.000 54.99381  ? 83  TYR   A O   1 
ATOM   647  C  CB  . TYR   A 1 86  ? -21.30482 15.76260 -42.21309 1.000 50.67350  ? 83  TYR   A CB  1 
ATOM   648  C  CG  . TYR   A 1 86  ? -20.68240 15.18379 -40.95085 1.000 59.14710  ? 83  TYR   A CG  1 
ATOM   649  C  CD1 . TYR   A 1 86  ? -19.38629 14.67490 -40.94793 1.000 59.57569  ? 83  TYR   A CD1 1 
ATOM   650  C  CD2 . TYR   A 1 86  ? -21.40061 15.14319 -39.75913 1.000 57.16245  ? 83  TYR   A CD2 1 
ATOM   651  C  CE1 . TYR   A 1 86  ? -18.82801 14.14160 -39.79646 1.000 51.65930  ? 83  TYR   A CE1 1 
ATOM   652  C  CE2 . TYR   A 1 86  ? -20.84842 14.61451 -38.60527 1.000 54.95313  ? 83  TYR   A CE2 1 
ATOM   653  C  CZ  . TYR   A 1 86  ? -19.56412 14.11504 -38.62905 1.000 59.34768  ? 83  TYR   A CZ  1 
ATOM   654  O  OH  . TYR   A 1 86  ? -19.01555 13.58884 -37.47962 1.000 60.55185  ? 83  TYR   A OH  1 
ATOM   655  N  N   . MET   A 1 87  ? -22.23396 13.08682 -43.42303 1.000 51.86122  ? 84  MET   A N   1 
ATOM   656  C  CA  . MET   A 1 87  ? -22.43833 11.64465 -43.32769 1.000 56.56913  ? 84  MET   A CA  1 
ATOM   657  C  C   . MET   A 1 87  ? -21.88754 10.92312 -44.55045 1.000 52.50458  ? 84  MET   A C   1 
ATOM   658  O  O   . MET   A 1 87  ? -21.28898 9.84714  -44.42786 1.000 51.28933  ? 84  MET   A O   1 
ATOM   659  C  CB  . MET   A 1 87  ? -23.92434 11.33306 -43.14725 1.000 54.55514  ? 84  MET   A CB  1 
ATOM   660  C  CG  . MET   A 1 87  ? -24.48526 11.73378 -41.79295 1.000 59.72947  ? 84  MET   A CG  1 
ATOM   661  S  SD  . MET   A 1 87  ? -23.83255 10.69767 -40.46927 1.000 66.51631  ? 84  MET   A SD  1 
ATOM   662  C  CE  . MET   A 1 87  ? -22.71382 11.83477 -39.65678 1.000 56.98221  ? 84  MET   A CE  1 
ATOM   663  N  N   . SER   A 1 88  ? -22.07445 11.49896 -45.73880 1.000 57.57677  ? 85  SER   A N   1 
ATOM   664  C  CA  A SER   A 1 88  ? -21.58218 10.85227 -46.94953 0.514 57.11799  ? 85  SER   A CA  1 
ATOM   665  C  CA  B SER   A 1 88  ? -21.58200 10.85217 -46.95086 0.486 57.12635  ? 85  SER   A CA  1 
ATOM   666  C  C   . SER   A 1 88  ? -20.06088 10.76745 -46.94750 1.000 54.36469  ? 85  SER   A C   1 
ATOM   667  O  O   . SER   A 1 88  ? -19.48542 9.77558  -47.41123 1.000 57.31205  ? 85  SER   A O   1 
ATOM   668  C  CB  A SER   A 1 88  ? -22.08806 11.60184 -48.18035 0.514 56.29316  ? 85  SER   A CB  1 
ATOM   669  C  CB  B SER   A 1 88  ? -22.08093 11.60009 -48.18775 0.486 56.27521  ? 85  SER   A CB  1 
ATOM   670  O  OG  A SER   A 1 88  ? -23.50522 11.65544 -48.18300 0.514 58.90317  ? 85  SER   A OG  1 
ATOM   671  O  OG  B SER   A 1 88  ? -21.76479 10.89567 -49.37747 0.486 56.76610  ? 85  SER   A OG  1 
ATOM   672  N  N   . ALA   A 1 89  ? -19.39135 11.79665 -46.42242 1.000 54.27206  ? 86  ALA   A N   1 
ATOM   673  C  CA  . ALA   A 1 89  ? -17.93510 11.76023 -46.33211 1.000 50.95591  ? 86  ALA   A CA  1 
ATOM   674  C  C   . ALA   A 1 89  ? -17.48005 10.81853 -45.22738 1.000 52.50650  ? 86  ALA   A C   1 
ATOM   675  O  O   . ALA   A 1 89  ? -16.47026 10.11856 -45.37480 1.000 49.52060  ? 86  ALA   A O   1 
ATOM   676  C  CB  . ALA   A 1 89  ? -17.38508 13.16619 -46.09846 1.000 42.85585  ? 86  ALA   A CB  1 
ATOM   677  N  N   . LEU   A 1 90  ? -18.21439 10.79493 -44.11105 1.000 57.33547  ? 87  LEU   A N   1 
ATOM   678  C  CA  . LEU   A 1 90  ? -17.86060 9.92823  -42.99199 1.000 48.74217  ? 87  LEU   A CA  1 
ATOM   679  C  C   . LEU   A 1 90  ? -17.90745 8.45746  -43.37877 1.000 52.08373  ? 87  LEU   A C   1 
ATOM   680  O  O   . LEU   A 1 90  ? -17.10967 7.65937  -42.87434 1.000 52.93936  ? 87  LEU   A O   1 
ATOM   681  C  CB  . LEU   A 1 90  ? -18.79873 10.19878 -41.81535 1.000 52.76107  ? 87  LEU   A CB  1 
ATOM   682  C  CG  . LEU   A 1 90  ? -18.63254 9.34030  -40.56161 1.000 53.77066  ? 87  LEU   A CG  1 
ATOM   683  C  CD1 . LEU   A 1 90  ? -17.19393 9.38851  -40.05507 1.000 50.13878  ? 87  LEU   A CD1 1 
ATOM   684  C  CD2 . LEU   A 1 90  ? -19.60482 9.80146  -39.48875 1.000 51.10345  ? 87  LEU   A CD2 1 
ATOM   685  N  N   . ASN   A 1 91  ? -18.80778 8.08469  -44.29129 1.000 57.37298  ? 88  ASN   A N   1 
ATOM   686  C  CA  . ASN   A 1 91  ? -18.89734 6.69067  -44.70844 1.000 61.58834  ? 88  ASN   A CA  1 
ATOM   687  C  C   . ASN   A 1 91  ? -17.59694 6.19832  -45.33124 1.000 60.26787  ? 88  ASN   A C   1 
ATOM   688  O  O   . ASN   A 1 91  ? -17.31568 4.99545  -45.30960 1.000 69.60184  ? 88  ASN   A O   1 
ATOM   689  C  CB  . ASN   A 1 91  ? -20.05784 6.51607  -45.69049 1.000 55.96489  ? 88  ASN   A CB  1 
ATOM   690  C  CG  . ASN   A 1 91  ? -20.54607 5.08722  -45.76654 1.000 69.43190  ? 88  ASN   A CG  1 
ATOM   691  O  OD1 . ASN   A 1 91  ? -20.80398 4.45099  -44.74173 1.000 75.96899  ? 88  ASN   A OD1 1 
ATOM   692  N  ND2 . ASN   A 1 91  ? -20.65662 4.56456  -46.98248 1.000 73.31662  ? 88  ASN   A ND2 1 
ATOM   693  N  N   . HIS   A 1 92  ? -16.79211 7.10228  -45.87753 1.000 54.20843  ? 89  HIS   A N   1 
ATOM   694  C  CA  . HIS   A 1 92  ? -15.49978 6.74631  -46.44299 1.000 58.64701  ? 89  HIS   A CA  1 
ATOM   695  C  C   . HIS   A 1 92  ? -14.34671 6.94929  -45.46921 1.000 55.44141  ? 89  HIS   A C   1 
ATOM   696  O  O   . HIS   A 1 92  ? -13.47386 6.08132  -45.36033 1.000 56.02618  ? 89  HIS   A O   1 
ATOM   697  C  CB  . HIS   A 1 92  ? -15.26026 7.55677  -47.72171 1.000 58.65842  ? 89  HIS   A CB  1 
ATOM   698  C  CG  . HIS   A 1 92  ? -16.24621 7.25686  -48.80249 1.000 69.50496  ? 89  HIS   A CG  1 
ATOM   699  N  ND1 . HIS   A 1 92  ? -16.23469 6.07608  -49.50495 1.000 74.94623  ? 89  HIS   A ND1 1 
ATOM   700  C  CD2 . HIS   A 1 92  ? -17.29402 7.96651  -49.28425 1.000 68.85880  ? 89  HIS   A CD2 1 
ATOM   701  C  CE1 . HIS   A 1 92  ? -17.21279 6.07619  -50.39204 1.000 72.69416  ? 89  HIS   A CE1 1 
ATOM   702  N  NE2 . HIS   A 1 92  ? -17.87701 7.21068  -50.27417 1.000 72.21370  ? 89  HIS   A NE2 1 
ATOM   703  N  N   . THR   A 1 93  ? -14.32651 8.07742  -44.75581 1.000 52.81807  ? 90  THR   A N   1 
ATOM   704  C  CA  . THR   A 1 93  ? -13.19541 8.37863  -43.88567 1.000 57.00054  ? 90  THR   A CA  1 
ATOM   705  C  C   . THR   A 1 93  ? -13.09245 7.39639  -42.72696 1.000 56.01155  ? 90  THR   A C   1 
ATOM   706  O  O   . THR   A 1 93  ? -11.99584 7.18870  -42.19414 1.000 56.44000  ? 90  THR   A O   1 
ATOM   707  C  CB  . THR   A 1 93  ? -13.29002 9.80723  -43.34487 1.000 52.88875  ? 90  THR   A CB  1 
ATOM   708  O  OG1 . THR   A 1 93  ? -14.48049 9.94761  -42.56277 1.000 54.11791  ? 90  THR   A OG1 1 
ATOM   709  C  CG2 . THR   A 1 93  ? -13.31190 10.81026 -44.48436 1.000 47.34477  ? 90  THR   A CG2 1 
ATOM   710  N  N   . LYS   A 1 94  ? -14.20842 6.78260  -42.32486 1.000 52.73855  ? 91  LYS   A N   1 
ATOM   711  C  CA  . LYS   A 1 94  ? -14.16186 5.74742  -41.29714 1.000 51.39270  ? 91  LYS   A CA  1 
ATOM   712  C  C   . LYS   A 1 94  ? -13.44452 4.48967  -41.77105 1.000 50.86221  ? 91  LYS   A C   1 
ATOM   713  O  O   . LYS   A 1 94  ? -13.10941 3.63986  -40.94032 1.000 59.88430  ? 91  LYS   A O   1 
ATOM   714  C  CB  . LYS   A 1 94  ? -15.57812 5.39571  -40.82470 1.000 44.19375  ? 91  LYS   A CB  1 
ATOM   715  C  CG  . LYS   A 1 94  ? -16.38426 4.60202  -41.83936 1.000 72.41256  ? 91  LYS   A CG  1 
ATOM   716  C  CD  . LYS   A 1 94  ? -17.77794 4.25769  -41.33284 1.000 73.53599  ? 91  LYS   A CD  1 
ATOM   717  C  CE  . LYS   A 1 94  ? -18.59027 3.56204  -42.42221 1.000 77.65095  ? 91  LYS   A CE  1 
ATOM   718  N  NZ  . LYS   A 1 94  ? -19.96331 3.20841  -41.96548 1.000 80.26128  ? 91  LYS   A NZ  1 
ATOM   719  N  N   . LYS   A 1 95  ? -13.19943 4.35225  -43.07531 1.000 63.10680  ? 92  LYS   A N   1 
ATOM   720  C  CA  . LYS   A 1 95  ? -12.46068 3.22113  -43.61908 1.000 60.07313  ? 92  LYS   A CA  1 
ATOM   721  C  C   . LYS   A 1 95  ? -10.98093 3.52358  -43.81773 1.000 58.57105  ? 92  LYS   A C   1 
ATOM   722  O  O   . LYS   A 1 95  ? -10.21350 2.60671  -44.12974 1.000 59.03728  ? 92  LYS   A O   1 
ATOM   723  C  CB  . LYS   A 1 95  ? -13.06998 2.78365  -44.95776 1.000 66.04920  ? 92  LYS   A CB  1 
ATOM   724  C  CG  . LYS   A 1 95  ? -14.50784 2.27932  -44.87157 1.000 73.40110  ? 92  LYS   A CG  1 
ATOM   725  C  CD  . LYS   A 1 95  ? -15.06400 1.97145  -46.26073 1.000 88.92460  ? 92  LYS   A CD  1 
ATOM   726  C  CE  . LYS   A 1 95  ? -16.53379 1.58325  -46.20399 1.000 85.74206  ? 92  LYS   A CE  1 
ATOM   727  N  NZ  . LYS   A 1 95  ? -16.77344 0.47464  -45.23943 1.000 101.03264 ? 92  LYS   A NZ  1 
ATOM   728  N  N   . TRP   A 1 96  ? -10.56622 4.77685  -43.64702 1.000 57.84508  ? 93  TRP   A N   1 
ATOM   729  C  CA  . TRP   A 1 96  ? -9.15903  5.13164  -43.74122 1.000 60.71322  ? 93  TRP   A CA  1 
ATOM   730  C  C   . TRP   A 1 96  ? -8.40005  4.65595  -42.50325 1.000 59.10881  ? 93  TRP   A C   1 
ATOM   731  O  O   . TRP   A 1 96  ? -8.97919  4.38415  -41.44747 1.000 61.87964  ? 93  TRP   A O   1 
ATOM   732  C  CB  . TRP   A 1 96  ? -8.99637  6.64631  -43.88999 1.000 49.75946  ? 93  TRP   A CB  1 
ATOM   733  C  CG  . TRP   A 1 96  ? -9.49479  7.19885  -45.18906 1.000 58.13306  ? 93  TRP   A CG  1 
ATOM   734  C  CD1 . TRP   A 1 96  ? -9.92410  6.48948  -46.27092 1.000 57.76054  ? 93  TRP   A CD1 1 
ATOM   735  C  CD2 . TRP   A 1 96  ? -9.63469  8.58459  -45.53664 1.000 61.07195  ? 93  TRP   A CD2 1 
ATOM   736  N  NE1 . TRP   A 1 96  ? -10.31011 7.34543  -47.27557 1.000 58.71585  ? 93  TRP   A NE1 1 
ATOM   737  C  CE2 . TRP   A 1 96  ? -10.14339 8.63645  -46.84954 1.000 54.06654  ? 93  TRP   A CE2 1 
ATOM   738  C  CE3 . TRP   A 1 96  ? -9.37475  9.78508  -44.86620 1.000 54.60422  ? 93  TRP   A CE3 1 
ATOM   739  C  CZ2 . TRP   A 1 96  ? -10.39745 9.83962  -47.50530 1.000 51.92920  ? 93  TRP   A CZ2 1 
ATOM   740  C  CZ3 . TRP   A 1 96  ? -9.62776  10.98038 -45.52052 1.000 52.92097  ? 93  TRP   A CZ3 1 
ATOM   741  C  CH2 . TRP   A 1 96  ? -10.13380 10.99727 -46.82614 1.000 51.30053  ? 93  TRP   A CH2 1 
ATOM   742  N  N   . LYS   A 1 97  ? -7.08221  4.56754  -42.64396 1.000 51.44176  ? 94  LYS   A N   1 
ATOM   743  C  CA  . LYS   A 1 97  ? -6.18856  4.25281  -41.53803 1.000 50.15320  ? 94  LYS   A CA  1 
ATOM   744  C  C   . LYS   A 1 97  ? -5.46957  5.51555  -41.08708 1.000 54.26160  ? 94  LYS   A C   1 
ATOM   745  O  O   . LYS   A 1 97  ? -4.99777  6.30171  -41.91331 1.000 55.72728  ? 94  LYS   A O   1 
ATOM   746  C  CB  . LYS   A 1 97  ? -5.16626  3.17905  -41.92324 1.000 52.55280  ? 94  LYS   A CB  1 
ATOM   747  C  CG  . LYS   A 1 97  ? -5.62605  1.73051  -41.75189 1.000 53.96364  ? 94  LYS   A CG  1 
ATOM   748  C  CD  . LYS   A 1 97  ? -6.97171  1.42128  -42.37811 1.000 70.14158  ? 94  LYS   A CD  1 
ATOM   749  C  CE  . LYS   A 1 97  ? -7.38089  -0.01422 -42.07165 1.000 78.31719  ? 94  LYS   A CE  1 
ATOM   750  N  NZ  . LYS   A 1 97  ? -8.71409  -0.36034 -42.63818 1.000 91.94511  ? 94  LYS   A NZ  1 
ATOM   751  N  N   . TYR   A 1 98  ? -5.39218  5.70937  -39.76827 1.000 47.82640  ? 95  TYR   A N   1 
ATOM   752  C  CA  . TYR   A 1 98  ? -4.82948  6.91956  -39.17387 1.000 50.97745  ? 95  TYR   A CA  1 
ATOM   753  C  C   . TYR   A 1 98  ? -3.65496  6.53586  -38.28111 1.000 53.53219  ? 95  TYR   A C   1 
ATOM   754  O  O   . TYR   A 1 98  ? -3.76802  6.55194  -37.04607 1.000 56.41520  ? 95  TYR   A O   1 
ATOM   755  C  CB  . TYR   A 1 98  ? -5.89637  7.68597  -38.39519 1.000 46.95964  ? 95  TYR   A CB  1 
ATOM   756  C  CG  . TYR   A 1 98  ? -7.07227  8.08225  -39.25368 1.000 52.78781  ? 95  TYR   A CG  1 
ATOM   757  C  CD1 . TYR   A 1 98  ? -7.01565  9.20131  -40.07253 1.000 52.81477  ? 95  TYR   A CD1 1 
ATOM   758  C  CD2 . TYR   A 1 98  ? -8.23152  7.31956  -39.26530 1.000 55.19165  ? 95  TYR   A CD2 1 
ATOM   759  C  CE1 . TYR   A 1 98  ? -8.08890  9.56094  -40.86415 1.000 46.10914  ? 95  TYR   A CE1 1 
ATOM   760  C  CE2 . TYR   A 1 98  ? -9.30821  7.66981  -40.05380 1.000 49.84460  ? 95  TYR   A CE2 1 
ATOM   761  C  CZ  . TYR   A 1 98  ? -9.23195  8.79058  -40.85043 1.000 50.13938  ? 95  TYR   A CZ  1 
ATOM   762  O  OH  . TYR   A 1 98  ? -10.30190 9.14349  -41.63965 1.000 57.09317  ? 95  TYR   A OH  1 
ATOM   763  N  N   . PRO   A 1 99  ? -2.50627  6.20710  -38.86702 1.000 58.14411  ? 96  PRO   A N   1 
ATOM   764  C  CA  . PRO   A 1 99  ? -1.36919  5.77524  -38.05315 1.000 51.93968  ? 96  PRO   A CA  1 
ATOM   765  C  C   . PRO   A 1 99  ? -0.72151  6.94552  -37.33431 1.000 55.30860  ? 96  PRO   A C   1 
ATOM   766  O  O   . PRO   A 1 99  ? -0.79848  8.09626  -37.77011 1.000 54.14197  ? 96  PRO   A O   1 
ATOM   767  C  CB  . PRO   A 1 99  ? -0.41566  5.16086  -39.08261 1.000 48.04017  ? 96  PRO   A CB  1 
ATOM   768  C  CG  . PRO   A 1 99  ? -0.68837  5.93949  -40.32144 1.000 47.00777  ? 96  PRO   A CG  1 
ATOM   769  C  CD  . PRO   A 1 99  ? -2.16840  6.25509  -40.30070 1.000 55.64909  ? 96  PRO   A CD  1 
ATOM   770  N  N   . GLN   A 1 100 ? -0.08006  6.63494  -36.21131 1.000 59.74406  ? 97  GLN   A N   1 
ATOM   771  C  CA  . GLN   A 1 100 ? 0.70868   7.62202  -35.48674 1.000 52.78553  ? 97  GLN   A CA  1 
ATOM   772  C  C   . GLN   A 1 100 ? 2.09669   7.69076  -36.11121 1.000 52.03012  ? 97  GLN   A C   1 
ATOM   773  O  O   . GLN   A 1 100 ? 2.81086   6.68519  -36.15669 1.000 58.51222  ? 97  GLN   A O   1 
ATOM   774  C  CB  . GLN   A 1 100 ? 0.78737   7.25504  -34.00672 1.000 48.94127  ? 97  GLN   A CB  1 
ATOM   775  C  CG  . GLN   A 1 100 ? 0.92812   8.44431  -33.06331 1.000 67.15692  ? 97  GLN   A CG  1 
ATOM   776  C  CD  . GLN   A 1 100 ? -0.37267  9.20985  -32.88760 1.000 72.59279  ? 97  GLN   A CD  1 
ATOM   777  O  OE1 . GLN   A 1 100 ? -1.40562  8.84171  -33.45249 1.000 56.81193  ? 97  GLN   A OE1 1 
ATOM   778  N  NE2 . GLN   A 1 100 ? -0.32938  10.27995 -32.09591 1.000 75.83522  ? 97  GLN   A NE2 1 
ATOM   779  N  N   . VAL   A 1 101 ? 2.47344   8.86555  -36.60858 1.000 50.00207  ? 98  VAL   A N   1 
ATOM   780  C  CA  . VAL   A 1 101 ? 3.73560   9.06027  -37.31966 1.000 51.68500  ? 98  VAL   A CA  1 
ATOM   781  C  C   . VAL   A 1 101 ? 4.45891   10.22152 -36.65313 1.000 49.72533  ? 98  VAL   A C   1 
ATOM   782  O  O   . VAL   A 1 101 ? 3.97498   11.36076 -36.68636 1.000 50.73165  ? 98  VAL   A O   1 
ATOM   783  C  CB  . VAL   A 1 101 ? 3.52826   9.32428  -38.81675 1.000 53.09644  ? 98  VAL   A CB  1 
ATOM   784  C  CG1 . VAL   A 1 101 ? 4.85988   9.58323  -39.51502 1.000 47.16962  ? 98  VAL   A CG1 1 
ATOM   785  C  CG2 . VAL   A 1 101 ? 2.81854   8.15371  -39.46498 1.000 48.91490  ? 98  VAL   A CG2 1 
ATOM   786  N  N   . ASN   A 1 102 ? 5.61004   9.93714  -36.03922 1.000 59.31523  ? 99  ASN   A N   1 
ATOM   787  C  CA  . ASN   A 1 102 ? 6.42552   10.95246 -35.37339 1.000 55.45526  ? 99  ASN   A CA  1 
ATOM   788  C  C   . ASN   A 1 102 ? 5.61593   11.70562 -34.31858 1.000 58.92739  ? 99  ASN   A C   1 
ATOM   789  O  O   . ASN   A 1 102 ? 5.69976   12.93047 -34.19954 1.000 55.26752  ? 99  ASN   A O   1 
ATOM   790  C  CB  . ASN   A 1 102 ? 7.03743   11.92085 -36.38870 1.000 58.50057  ? 99  ASN   A CB  1 
ATOM   791  C  CG  . ASN   A 1 102 ? 8.16392   12.74399 -35.79978 1.000 65.47371  ? 99  ASN   A CG  1 
ATOM   792  O  OD1 . ASN   A 1 102 ? 8.10991   13.97579 -35.79122 1.000 64.13485  ? 99  ASN   A OD1 1 
ATOM   793  N  ND2 . ASN   A 1 102 ? 9.19286   12.06723 -35.30271 1.000 59.34858  ? 99  ASN   A ND2 1 
ATOM   794  N  N   . GLY   A 1 103 ? 4.81451   10.96604 -33.55309 1.000 53.79648  ? 100 GLY   A N   1 
ATOM   795  C  CA  . GLY   A 1 103 ? 3.99484   11.56694 -32.51942 1.000 57.69287  ? 100 GLY   A CA  1 
ATOM   796  C  C   . GLY   A 1 103 ? 2.80234   12.35197 -33.01178 1.000 60.00456  ? 100 GLY   A C   1 
ATOM   797  O  O   . GLY   A 1 103 ? 2.20396   13.09746 -32.22809 1.000 64.29981  ? 100 GLY   A O   1 
ATOM   798  N  N   . LEU   A 1 104 ? 2.42780   12.19717 -34.28027 1.000 54.87236  ? 101 LEU   A N   1 
ATOM   799  C  CA  . LEU   A 1 104 ? 1.29630   12.90106 -34.86272 1.000 50.68828  ? 101 LEU   A CA  1 
ATOM   800  C  C   . LEU   A 1 104 ? 0.37648   11.90212 -35.54690 1.000 52.58801  ? 101 LEU   A C   1 
ATOM   801  O  O   . LEU   A 1 104 ? 0.81574   10.84728 -36.01312 1.000 56.73436  ? 101 LEU   A O   1 
ATOM   802  C  CB  . LEU   A 1 104 ? 1.75243   13.96591 -35.86927 1.000 44.40194  ? 101 LEU   A CB  1 
ATOM   803  C  CG  . LEU   A 1 104 ? 2.56091   15.12395 -35.28064 1.000 49.54838  ? 101 LEU   A CG  1 
ATOM   804  C  CD1 . LEU   A 1 104 ? 3.37587   15.81592 -36.35984 1.000 39.78953  ? 101 LEU   A CD1 1 
ATOM   805  C  CD2 . LEU   A 1 104 ? 1.65526   16.11994 -34.56327 1.000 39.40703  ? 101 LEU   A CD2 1 
ATOM   806  N  N   . THR   A 1 105 ? -0.90774  12.24315 -35.60126 1.000 53.29104  ? 102 THR   A N   1 
ATOM   807  C  CA  . THR   A 1 105 ? -1.89540  11.42641 -36.29412 1.000 51.90078  ? 102 THR   A CA  1 
ATOM   808  C  C   . THR   A 1 105 ? -1.89984  11.80465 -37.76949 1.000 53.65117  ? 102 THR   A C   1 
ATOM   809  O  O   . THR   A 1 105 ? -2.19793  12.95143 -38.12062 1.000 52.74837  ? 102 THR   A O   1 
ATOM   810  C  CB  . THR   A 1 105 ? -3.28710  11.61409 -35.69388 1.000 47.95482  ? 102 THR   A CB  1 
ATOM   811  O  OG1 . THR   A 1 105 ? -3.25383  11.31400 -34.29400 1.000 60.19400  ? 102 THR   A OG1 1 
ATOM   812  C  CG2 . THR   A 1 105 ? -4.28066  10.69283 -36.37456 1.000 53.29716  ? 102 THR   A CG2 1 
ATOM   813  N  N   . SER   A 1 106 ? -1.55872  10.84622 -38.62362 1.000 51.90618  ? 103 SER   A N   1 
ATOM   814  C  CA  . SER   A 1 106 ? -1.53270  11.02283 -40.06521 1.000 53.48614  ? 103 SER   A CA  1 
ATOM   815  C  C   . SER   A 1 106 ? -2.63034  10.17625 -40.70768 1.000 54.59777  ? 103 SER   A C   1 
ATOM   816  O  O   . SER   A 1 106 ? -3.48999  9.61030  -40.02511 1.000 49.15231  ? 103 SER   A O   1 
ATOM   817  C  CB  . SER   A 1 106 ? -0.14841  10.67200 -40.60939 1.000 51.96875  ? 103 SER   A CB  1 
ATOM   818  O  OG  . SER   A 1 106 ? 0.02068   11.18202 -41.91814 1.000 51.46985  ? 103 SER   A OG  1 
ATOM   819  N  N   . ILE   A 1 107 ? -2.61792  10.10943 -42.03698 1.000 58.96779  ? 104 ILE   A N   1 
ATOM   820  C  CA  . ILE   A 1 107 ? -3.57990  9.31587  -42.79236 1.000 54.17091  ? 104 ILE   A CA  1 
ATOM   821  C  C   . ILE   A 1 107 ? -2.82794  8.47255  -43.81002 1.000 50.60275  ? 104 ILE   A C   1 
ATOM   822  O  O   . ILE   A 1 107 ? -2.03175  9.00495  -44.59070 1.000 50.96441  ? 104 ILE   A O   1 
ATOM   823  C  CB  . ILE   A 1 107 ? -4.62738  10.18755 -43.51038 1.000 49.11205  ? 104 ILE   A CB  1 
ATOM   824  C  CG1 . ILE   A 1 107 ? -5.03016  11.39276 -42.65839 1.000 51.35979  ? 104 ILE   A CG1 1 
ATOM   825  C  CG2 . ILE   A 1 107 ? -5.84328  9.34876  -43.84897 1.000 46.95767  ? 104 ILE   A CG2 1 
ATOM   826  C  CD1 . ILE   A 1 107 ? -5.95645  12.35183 -43.37361 1.000 45.48562  ? 104 ILE   A CD1 1 
ATOM   827  N  N   . LYS   A 1 108 ? -3.06308  7.16059  -43.78848 1.000 52.82152  ? 105 LYS   A N   1 
ATOM   828  C  CA  . LYS   A 1 108 ? -2.61366  6.31119  -44.88438 1.000 57.46702  ? 105 LYS   A CA  1 
ATOM   829  C  C   . LYS   A 1 108 ? -3.30190  6.73928  -46.17529 1.000 56.90177  ? 105 LYS   A C   1 
ATOM   830  O  O   . LYS   A 1 108 ? -4.49643  7.05015  -46.18315 1.000 52.31248  ? 105 LYS   A O   1 
ATOM   831  C  CB  . LYS   A 1 108 ? -2.91717  4.84180  -44.58823 1.000 54.81359  ? 105 LYS   A CB  1 
ATOM   832  C  CG  . LYS   A 1 108 ? -2.51087  3.89907  -45.71167 1.000 63.26967  ? 105 LYS   A CG  1 
ATOM   833  C  CD  . LYS   A 1 108 ? -3.00943  2.48129  -45.48315 1.000 64.39416  ? 105 LYS   A CD  1 
ATOM   834  C  CE  . LYS   A 1 108 ? -2.53876  1.55547  -46.59603 1.000 70.19982  ? 105 LYS   A CE  1 
ATOM   835  N  NZ  . LYS   A 1 108 ? -3.05667  0.16982  -46.43487 1.000 94.72304  ? 105 LYS   A NZ  1 
ATOM   836  N  N   . TRP   A 1 109 ? -2.54120  6.76949  -47.26950 1.000 58.82607  ? 106 TRP   A N   1 
ATOM   837  C  CA  . TRP   A 1 109 ? -3.05364  7.35338  -48.50346 1.000 56.76104  ? 106 TRP   A CA  1 
ATOM   838  C  C   . TRP   A 1 109 ? -4.26888  6.59297  -49.02011 1.000 58.87560  ? 106 TRP   A C   1 
ATOM   839  O  O   . TRP   A 1 109 ? -4.29614  5.35834  -49.03890 1.000 60.35068  ? 106 TRP   A O   1 
ATOM   840  C  CB  . TRP   A 1 109 ? -1.98076  7.38911  -49.59056 1.000 52.94661  ? 106 TRP   A CB  1 
ATOM   841  C  CG  . TRP   A 1 109 ? -2.46996  8.13311  -50.80206 1.000 60.10700  ? 106 TRP   A CG  1 
ATOM   842  C  CD1 . TRP   A 1 109 ? -2.33652  9.46815  -51.05023 1.000 54.18923  ? 106 TRP   A CD1 1 
ATOM   843  C  CD2 . TRP   A 1 109 ? -3.20900  7.59244  -51.90795 1.000 62.21497  ? 106 TRP   A CD2 1 
ATOM   844  N  NE1 . TRP   A 1 109 ? -2.93201  9.79033  -52.24583 1.000 65.10995  ? 106 TRP   A NE1 1 
ATOM   845  C  CE2 . TRP   A 1 109 ? -3.47445  8.65724  -52.79280 1.000 66.75386  ? 106 TRP   A CE2 1 
ATOM   846  C  CE3 . TRP   A 1 109 ? -3.66391  6.31086  -52.23929 1.000 60.49395  ? 106 TRP   A CE3 1 
ATOM   847  C  CZ2 . TRP   A 1 109 ? -4.17285  8.48054  -53.98778 1.000 67.75458  ? 106 TRP   A CZ2 1 
ATOM   848  C  CZ3 . TRP   A 1 109 ? -4.35941  6.13793  -53.42548 1.000 64.83589  ? 106 TRP   A CZ3 1 
ATOM   849  C  CH2 . TRP   A 1 109 ? -4.60588  7.21706  -54.28499 1.000 64.83927  ? 106 TRP   A CH2 1 
ATOM   850  N  N   . ALA   A 1 110 ? -5.27039  7.35165  -49.45803 1.000 54.32104  ? 107 ALA   A N   1 
ATOM   851  C  CA  . ALA   A 1 110 ? -6.49015  6.82713  -50.05178 1.000 56.42940  ? 107 ALA   A CA  1 
ATOM   852  C  C   . ALA   A 1 110 ? -7.27476  7.99764  -50.61989 1.000 54.81802  ? 107 ALA   A C   1 
ATOM   853  O  O   . ALA   A 1 110 ? -7.22618  9.10014  -50.07333 1.000 58.57559  ? 107 ALA   A O   1 
ATOM   854  C  CB  . ALA   A 1 110 ? -7.33698  6.06769  -49.02074 1.000 56.96922  ? 107 ALA   A CB  1 
ATOM   855  N  N   . ASP   A 1 111 ? -7.98092  7.75624  -51.72526 1.000 55.14041  ? 108 ASP   A N   1 
ATOM   856  C  CA  . ASP   A 1 111 ? -8.94446  8.72555  -52.25078 1.000 49.93306  ? 108 ASP   A CA  1 
ATOM   857  C  C   . ASP   A 1 111 ? -8.34841  10.12951 -52.37576 1.000 55.10969  ? 108 ASP   A C   1 
ATOM   858  O  O   . ASP   A 1 111 ? -9.02423  11.13492 -52.14856 1.000 64.28203  ? 108 ASP   A O   1 
ATOM   859  C  CB  . ASP   A 1 111 ? -10.19709 8.72798  -51.36632 1.000 53.40163  ? 108 ASP   A CB  1 
ATOM   860  C  CG  . ASP   A 1 111 ? -10.93436 7.38972  -51.39291 1.000 67.10155  ? 108 ASP   A CG  1 
ATOM   861  O  OD1 . ASP   A 1 111 ? -10.91298 6.73194  -52.45521 1.000 84.98699  ? 108 ASP   A OD1 1 
ATOM   862  O  OD2 . ASP   A 1 111 ? -11.45804 6.94948  -50.34572 1.000 64.09572  ? 108 ASP   A OD2 1 
ATOM   863  N  N   . ASN   A 1 112 ? -7.06666  10.19744 -52.74703 1.000 51.14328  ? 109 ASN   A N   1 
ATOM   864  C  CA  . ASN   A 1 112 ? -6.37692  11.46796 -52.99845 1.000 56.28245  ? 109 ASN   A CA  1 
ATOM   865  C  C   . ASN   A 1 112 ? -6.40723  12.38710 -51.77508 1.000 55.52742  ? 109 ASN   A C   1 
ATOM   866  O  O   . ASN   A 1 112 ? -6.71842  13.57600 -51.87189 1.000 56.38400  ? 109 ASN   A O   1 
ATOM   867  C  CB  . ASN   A 1 112 ? -6.95312  12.18758 -54.22308 1.000 62.83514  ? 109 ASN   A CB  1 
ATOM   868  C  CG  . ASN   A 1 112 ? -6.73555  11.42524 -55.51882 1.000 66.93794  ? 109 ASN   A CG  1 
ATOM   869  O  OD1 . ASN   A 1 112 ? -5.67948  10.82915 -55.74244 1.000 69.13146  ? 109 ASN   A OD1 1 
ATOM   870  N  ND2 . ASN   A 1 112 ? -7.73855  11.45296 -56.38795 1.000 66.21899  ? 109 ASN   A ND2 1 
ATOM   871  N  N   . ASN   A 1 113 ? -6.06976  11.83509 -50.60900 1.000 59.90383  ? 110 ASN   A N   1 
ATOM   872  C  CA  . ASN   A 1 113 ? -6.12475  12.60306 -49.37233 1.000 55.13716  ? 110 ASN   A CA  1 
ATOM   873  C  C   . ASN   A 1 113 ? -4.77014  13.18592 -48.98161 1.000 50.16700  ? 110 ASN   A C   1 
ATOM   874  O  O   . ASN   A 1 113 ? -4.56146  13.50609 -47.80796 1.000 55.78034  ? 110 ASN   A O   1 
ATOM   875  C  CB  . ASN   A 1 113 ? -6.67899  11.74441 -48.23290 1.000 50.10127  ? 110 ASN   A CB  1 
ATOM   876  C  CG  . ASN   A 1 113 ? -5.83925  10.50824 -47.96496 1.000 56.70473  ? 110 ASN   A CG  1 
ATOM   877  O  OD1 . ASN   A 1 113 ? -4.77193  10.31846 -48.55274 1.000 50.32690  ? 110 ASN   A OD1 1 
ATOM   878  N  ND2 . ASN   A 1 113 ? -6.33200  9.64776  -47.08166 1.000 48.75222  ? 110 ASN   A ND2 1 
ATOM   879  N  N   . CYS   A 1 114 ? -3.85341  13.33961 -49.94270 1.000 54.36958  ? 111 CYS   A N   1 
ATOM   880  C  CA  . CYS   A 1 114 ? -2.53434  13.88973 -49.63570 1.000 47.49352  ? 111 CYS   A CA  1 
ATOM   881  C  C   . CYS   A 1 114 ? -2.64621  15.25000 -48.95648 1.000 53.14743  ? 111 CYS   A C   1 
ATOM   882  O  O   . CYS   A 1 114 ? -1.93111  15.52738 -47.98610 1.000 58.68633  ? 111 CYS   A O   1 
ATOM   883  C  CB  . CYS   A 1 114 ? -1.69009  13.98643 -50.91179 1.000 47.58880  ? 111 CYS   A CB  1 
ATOM   884  S  SG  . CYS   A 1 114 ? -2.02494  15.43430 -51.98222 1.000 81.82996  ? 111 CYS   A SG  1 
ATOM   885  N  N   . TYR   A 1 115 ? -3.53797  16.11083 -49.44659 1.000 50.94973  ? 112 TYR   A N   1 
ATOM   886  C  CA  . TYR   A 1 115 ? -3.66594  17.43648 -48.85393 1.000 47.14537  ? 112 TYR   A CA  1 
ATOM   887  C  C   . TYR   A 1 115 ? -4.34644  17.38651 -47.49369 1.000 50.73170  ? 112 TYR   A C   1 
ATOM   888  O  O   . TYR   A 1 115 ? -4.03765  18.20520 -46.62054 1.000 55.72798  ? 112 TYR   A O   1 
ATOM   889  C  CB  . TYR   A 1 115 ? -4.43081  18.36533 -49.79437 1.000 51.48578  ? 112 TYR   A CB  1 
ATOM   890  C  CG  . TYR   A 1 115 ? -5.92470  18.14363 -49.81867 1.000 44.21841  ? 112 TYR   A CG  1 
ATOM   891  C  CD1 . TYR   A 1 115 ? -6.47427  17.02724 -50.43566 1.000 48.41432  ? 112 TYR   A CD1 1 
ATOM   892  C  CD2 . TYR   A 1 115 ? -6.78686  19.05913 -49.23402 1.000 42.82416  ? 112 TYR   A CD2 1 
ATOM   893  C  CE1 . TYR   A 1 115 ? -7.84324  16.82925 -50.46417 1.000 53.80039  ? 112 TYR   A CE1 1 
ATOM   894  C  CE2 . TYR   A 1 115 ? -8.15311  18.87087 -49.25655 1.000 47.48107  ? 112 TYR   A CE2 1 
ATOM   895  C  CZ  . TYR   A 1 115 ? -8.67823  17.75636 -49.87151 1.000 51.18471  ? 112 TYR   A CZ  1 
ATOM   896  O  OH  . TYR   A 1 115 ? -10.04385 17.57336 -49.89122 1.000 51.78661  ? 112 TYR   A OH  1 
ATOM   897  N  N   . LEU   A 1 116 ? -5.27792  16.45167 -47.29688 1.000 51.87111  ? 113 LEU   A N   1 
ATOM   898  C  CA  . LEU   A 1 116 ? -5.91872  16.31379 -45.99249 1.000 51.79745  ? 113 LEU   A CA  1 
ATOM   899  C  C   . LEU   A 1 116 ? -4.91906  15.86581 -44.93653 1.000 54.44380  ? 113 LEU   A C   1 
ATOM   900  O  O   . LEU   A 1 116 ? -4.92549  16.37425 -43.80945 1.000 54.35759  ? 113 LEU   A O   1 
ATOM   901  C  CB  . LEU   A 1 116 ? -7.08334  15.33005 -46.07494 1.000 53.57786  ? 113 LEU   A CB  1 
ATOM   902  C  CG  . LEU   A 1 116 ? -8.40701  15.94163 -46.52454 1.000 57.97955  ? 113 LEU   A CG  1 
ATOM   903  C  CD1 . LEU   A 1 116 ? -9.48874  14.87719 -46.61254 1.000 60.77043  ? 113 LEU   A CD1 1 
ATOM   904  C  CD2 . LEU   A 1 116 ? -8.80788  17.05572 -45.57154 1.000 46.27354  ? 113 LEU   A CD2 1 
ATOM   905  N  N   . ALA   A 1 117 ? -4.06379  14.90079 -45.27873 1.000 51.76452  ? 114 ALA   A N   1 
ATOM   906  C  CA  . ALA   A 1 117 ? -3.04728  14.45314 -44.33689 1.000 45.99755  ? 114 ALA   A CA  1 
ATOM   907  C  C   . ALA   A 1 117 ? -2.12850  15.60036 -43.93005 1.000 53.33756  ? 114 ALA   A C   1 
ATOM   908  O  O   . ALA   A 1 117 ? -1.79843  15.74787 -42.74859 1.000 52.82424  ? 114 ALA   A O   1 
ATOM   909  C  CB  . ALA   A 1 117 ? -2.24927  13.29773 -44.93806 1.000 42.76469  ? 114 ALA   A CB  1 
ATOM   910  N  N   . THR   A 1 118 ? -1.71120  16.42927 -44.89134 1.000 45.43720  ? 115 THR   A N   1 
ATOM   911  C  CA  . THR   A 1 118 ? -0.84228  17.55573 -44.56136 1.000 47.44720  ? 115 THR   A CA  1 
ATOM   912  C  C   . THR   A 1 118 ? -1.55593  18.56678 -43.67166 1.000 51.37056  ? 115 THR   A C   1 
ATOM   913  O  O   . THR   A 1 118 ? -0.95671  19.11323 -42.73691 1.000 50.66798  ? 115 THR   A O   1 
ATOM   914  C  CB  . THR   A 1 118 ? -0.33806  18.22243 -45.84121 1.000 52.30741  ? 115 THR   A CB  1 
ATOM   915  O  OG1 . THR   A 1 118 ? 0.46761   17.29223 -46.57308 1.000 53.28189  ? 115 THR   A OG1 1 
ATOM   916  C  CG2 . THR   A 1 118 ? 0.49654   19.45391 -45.52016 1.000 54.25512  ? 115 THR   A CG2 1 
ATOM   917  N  N   . ALA   A 1 119 ? -2.83381  18.83203 -43.94480 1.000 49.06325  ? 116 ALA   A N   1 
ATOM   918  C  CA  . ALA   A 1 119 ? -3.58897  19.74360 -43.09222 1.000 45.81879  ? 116 ALA   A CA  1 
ATOM   919  C  C   . ALA   A 1 119 ? -3.76852  19.16757 -41.69225 1.000 50.98402  ? 116 ALA   A C   1 
ATOM   920  O  O   . ALA   A 1 119 ? -3.59939  19.88022 -40.69600 1.000 50.58438  ? 116 ALA   A O   1 
ATOM   921  C  CB  . ALA   A 1 119 ? -4.93871  20.06313 -43.72998 1.000 38.66467  ? 116 ALA   A CB  1 
ATOM   922  N  N   . LEU   A 1 120 ? -4.11278  17.88072 -41.59851 1.000 49.86172  ? 117 LEU   A N   1 
ATOM   923  C  CA  . LEU   A 1 120 ? -4.29656  17.24909 -40.29458 1.000 48.54289  ? 117 LEU   A CA  1 
ATOM   924  C  C   . LEU   A 1 120 ? -3.02238  17.31257 -39.46135 1.000 53.00313  ? 117 LEU   A C   1 
ATOM   925  O  O   . LEU   A 1 120 ? -3.06965  17.60667 -38.26093 1.000 52.35634  ? 117 LEU   A O   1 
ATOM   926  C  CB  . LEU   A 1 120 ? -4.73935  15.79954 -40.47928 1.000 44.39575  ? 117 LEU   A CB  1 
ATOM   927  C  CG  . LEU   A 1 120 ? -4.94138  14.98105 -39.20750 1.000 49.09161  ? 117 LEU   A CG  1 
ATOM   928  C  CD1 . LEU   A 1 120 ? -5.98863  15.63535 -38.32502 1.000 45.49151  ? 117 LEU   A CD1 1 
ATOM   929  C  CD2 . LEU   A 1 120 ? -5.33221  13.55333 -39.55456 1.000 51.22052  ? 117 LEU   A CD2 1 
ATOM   930  N  N   . LEU   A 1 121 ? -1.87477  17.02883 -40.07806 1.000 46.60766  ? 118 LEU   A N   1 
ATOM   931  C  CA  . LEU   A 1 121 ? -0.61231  17.09145 -39.35205 1.000 46.29719  ? 118 LEU   A CA  1 
ATOM   932  C  C   . LEU   A 1 121 ? -0.31005  18.51157 -38.88673 1.000 52.83591  ? 118 LEU   A C   1 
ATOM   933  O  O   . LEU   A 1 121 ? 0.20608   18.71487 -37.78194 1.000 53.19199  ? 118 LEU   A O   1 
ATOM   934  C  CB  . LEU   A 1 121 ? 0.51562   16.55641 -40.23007 1.000 45.77560  ? 118 LEU   A CB  1 
ATOM   935  C  CG  . LEU   A 1 121 ? 0.39886   15.07692 -40.60677 1.000 52.70147  ? 118 LEU   A CG  1 
ATOM   936  C  CD1 . LEU   A 1 121 ? 1.34556   14.74025 -41.73868 1.000 47.07035  ? 118 LEU   A CD1 1 
ATOM   937  C  CD2 . LEU   A 1 121 ? 0.67090   14.18477 -39.40885 1.000 55.26156  ? 118 LEU   A CD2 1 
ATOM   938  N  N   . THR   A 1 122 ? -0.62795  19.50756 -39.71369 1.000 48.25091  ? 119 THR   A N   1 
ATOM   939  C  CA  . THR   A 1 122 ? -0.38416  20.89378 -39.32942 1.000 46.25513  ? 119 THR   A CA  1 
ATOM   940  C  C   . THR   A 1 122 ? -1.26568  21.31564 -38.16181 1.000 52.44835  ? 119 THR   A C   1 
ATOM   941  O  O   . THR   A 1 122 ? -0.79414  21.97313 -37.22460 1.000 52.78329  ? 119 THR   A O   1 
ATOM   942  C  CB  . THR   A 1 122 ? -0.61086  21.81335 -40.52522 1.000 48.95135  ? 119 THR   A CB  1 
ATOM   943  O  OG1 . THR   A 1 122 ? 0.32727   21.49056 -41.55650 1.000 51.08475  ? 119 THR   A OG1 1 
ATOM   944  C  CG2 . THR   A 1 122 ? -0.43225  23.25852 -40.11882 1.000 51.25683  ? 119 THR   A CG2 1 
ATOM   945  N  N   . LEU   A 1 123 ? -2.54948  20.95761 -38.20658 1.000 54.41291  ? 120 LEU   A N   1 
ATOM   946  C  CA  . LEU   A 1 123 ? -3.47611  21.37975 -37.16210 1.000 53.25295  ? 120 LEU   A CA  1 
ATOM   947  C  C   . LEU   A 1 123 ? -3.03684  20.89251 -35.78812 1.000 51.77798  ? 120 LEU   A C   1 
ATOM   948  O  O   . LEU   A 1 123 ? -3.31869  21.54699 -34.77916 1.000 58.85954  ? 120 LEU   A O   1 
ATOM   949  C  CB  . LEU   A 1 123 ? -4.88200  20.87322 -37.48019 1.000 47.64949  ? 120 LEU   A CB  1 
ATOM   950  C  CG  . LEU   A 1 123 ? -5.56021  21.46322 -38.71703 1.000 55.89895  ? 120 LEU   A CG  1 
ATOM   951  C  CD1 . LEU   A 1 123 ? -6.77006  20.63228 -39.10273 1.000 51.45772  ? 120 LEU   A CD1 1 
ATOM   952  C  CD2 . LEU   A 1 123 ? -5.96415  22.89795 -38.45089 1.000 54.13097  ? 120 LEU   A CD2 1 
ATOM   953  N  N   . GLN   A 1 124 ? -2.34671  19.75556 -35.72769 1.000 51.47405  ? 121 GLN   A N   1 
ATOM   954  C  CA  . GLN   A 1 124 ? -1.87169  19.19764 -34.46917 1.000 47.61267  ? 121 GLN   A CA  1 
ATOM   955  C  C   . GLN   A 1 124 ? -0.63326  19.90311 -33.93021 1.000 58.80495  ? 121 GLN   A C   1 
ATOM   956  O  O   . GLN   A 1 124 ? -0.14955  19.52948 -32.85682 1.000 64.67302  ? 121 GLN   A O   1 
ATOM   957  C  CB  . GLN   A 1 124 ? -1.57817  17.70701 -34.64076 1.000 46.42302  ? 121 GLN   A CB  1 
ATOM   958  C  CG  . GLN   A 1 124 ? -2.79451  16.87402 -34.98612 1.000 49.23827  ? 121 GLN   A CG  1 
ATOM   959  C  CD  . GLN   A 1 124 ? -2.42930  15.46739 -35.40965 1.000 50.44946  ? 121 GLN   A CD  1 
ATOM   960  O  OE1 . GLN   A 1 124 ? -2.11006  14.62038 -34.57472 1.000 56.75448  ? 121 GLN   A OE1 1 
ATOM   961  N  NE2 . GLN   A 1 124 ? -2.47463  15.20919 -36.71088 1.000 50.73548  ? 121 GLN   A NE2 1 
ATOM   962  N  N   . GLN   A 1 125 ? -0.10927  20.90604 -34.63558 1.000 56.31849  ? 122 GLN   A N   1 
ATOM   963  C  CA  . GLN   A 1 125 ? 1.11431   21.58034 -34.22679 1.000 51.26624  ? 122 GLN   A CA  1 
ATOM   964  C  C   . GLN   A 1 125 ? 0.94296   23.07921 -34.02638 1.000 51.44410  ? 122 GLN   A C   1 
ATOM   965  O  O   . GLN   A 1 125 ? 1.92784   23.76682 -33.73222 1.000 51.04712  ? 122 GLN   A O   1 
ATOM   966  C  CB  . GLN   A 1 125 ? 2.22573   21.32091 -35.25213 1.000 46.57719  ? 122 GLN   A CB  1 
ATOM   967  C  CG  . GLN   A 1 125 ? 2.54998   19.84967 -35.42055 1.000 49.21155  ? 122 GLN   A CG  1 
ATOM   968  C  CD  . GLN   A 1 125 ? 3.55757   19.59974 -36.51515 1.000 55.37711  ? 122 GLN   A CD  1 
ATOM   969  O  OE1 . GLN   A 1 125 ? 4.71558   20.00364 -36.41363 1.000 60.75569  ? 122 GLN   A OE1 1 
ATOM   970  N  NE2 . GLN   A 1 125 ? 3.12161   18.93719 -37.57576 1.000 56.49076  ? 122 GLN   A NE2 1 
ATOM   971  N  N   . ILE   A 1 126 ? -0.26884  23.60292 -34.16514 1.000 54.50914  ? 123 ILE   A N   1 
ATOM   972  C  CA  . ILE   A 1 126 ? -0.54846  25.01022 -33.92355 1.000 49.82109  ? 123 ILE   A CA  1 
ATOM   973  C  C   . ILE   A 1 126 ? -1.66015  25.11519 -32.88971 1.000 53.88297  ? 123 ILE   A C   1 
ATOM   974  O  O   . ILE   A 1 126 ? -2.49922  24.21739 -32.75792 1.000 59.69451  ? 123 ILE   A O   1 
ATOM   975  C  CB  . ILE   A 1 126 ? -0.92446  25.74717 -35.22465 1.000 55.22981  ? 123 ILE   A CB  1 
ATOM   976  C  CG1 . ILE   A 1 126 ? -2.10694  25.05726 -35.90755 1.000 57.22818  ? 123 ILE   A CG1 1 
ATOM   977  C  CG2 . ILE   A 1 126 ? 0.27154   25.80196 -36.15474 1.000 45.62321  ? 123 ILE   A CG2 1 
ATOM   978  C  CD1 . ILE   A 1 126 ? -2.51574  25.70348 -37.20793 1.000 55.58143  ? 123 ILE   A CD1 1 
ATOM   979  N  N   . GLU   A 1 127 ? -1.64951  26.21578 -32.13797 1.000 52.77698  ? 124 GLU   A N   1 
ATOM   980  C  CA  . GLU   A 1 127 ? -2.61673  26.42081 -31.06562 1.000 63.33177  ? 124 GLU   A CA  1 
ATOM   981  C  C   . GLU   A 1 127 ? -3.92734  26.91687 -31.66358 1.000 59.91270  ? 124 GLU   A C   1 
ATOM   982  O  O   . GLU   A 1 127 ? -3.98265  28.01231 -32.23449 1.000 56.24524  ? 124 GLU   A O   1 
ATOM   983  C  CB  . GLU   A 1 127 ? -2.06866  27.40953 -30.03822 1.000 68.94232  ? 124 GLU   A CB  1 
ATOM   984  C  CG  . GLU   A 1 127 ? -2.92504  27.56439 -28.78559 1.000 82.53575  ? 124 GLU   A CG  1 
ATOM   985  C  CD  . GLU   A 1 127 ? -2.23322  28.37969 -27.70096 1.000 120.71750 ? 124 GLU   A CD  1 
ATOM   986  O  OE1 . GLU   A 1 127 ? -1.10861  28.86636 -27.94555 1.000 120.41612 ? 124 GLU   A OE1 1 
ATOM   987  O  OE2 . GLU   A 1 127 ? -2.80814  28.52727 -26.60007 1.000 124.32575 ? 124 GLU   A OE2 1 
ATOM   988  N  N   . LEU   A 1 128 ? -4.98356  26.11909 -31.52345 1.000 49.17182  ? 125 LEU   A N   1 
ATOM   989  C  CA  . LEU   A 1 128 ? -6.22248  26.38251 -32.24061 1.000 54.05923  ? 125 LEU   A CA  1 
ATOM   990  C  C   . LEU   A 1 128 ? -7.40141  25.85922 -31.43669 1.000 54.02990  ? 125 LEU   A C   1 
ATOM   991  O  O   . LEU   A 1 128 ? -7.35514  24.73505 -30.92849 1.000 58.19736  ? 125 LEU   A O   1 
ATOM   992  C  CB  . LEU   A 1 128 ? -6.18478  25.71894 -33.62094 1.000 52.02417  ? 125 LEU   A CB  1 
ATOM   993  C  CG  . LEU   A 1 128 ? -6.75672  26.47125 -34.81791 1.000 58.86800  ? 125 LEU   A CG  1 
ATOM   994  C  CD1 . LEU   A 1 128 ? -6.16534  27.86206 -34.89735 1.000 59.58498  ? 125 LEU   A CD1 1 
ATOM   995  C  CD2 . LEU   A 1 128 ? -6.46038  25.70467 -36.09282 1.000 62.59131  ? 125 LEU   A CD2 1 
ATOM   996  N  N   . LYS   A 1 129 ? -8.44651  26.67437 -31.31482 1.000 52.79819  ? 126 LYS   A N   1 
ATOM   997  C  CA  . LYS   A 1 129 ? -9.71250  26.24938 -30.73050 1.000 56.74018  ? 126 LYS   A CA  1 
ATOM   998  C  C   . LYS   A 1 129 ? -10.82770 26.49089 -31.73743 1.000 65.03634  ? 126 LYS   A C   1 
ATOM   999  O  O   . LYS   A 1 129 ? -10.97917 27.60739 -32.24399 1.000 68.14278  ? 126 LYS   A O   1 
ATOM   1000 C  CB  . LYS   A 1 129 ? -10.01669 26.98993 -29.42690 1.000 59.70648  ? 126 LYS   A CB  1 
ATOM   1001 C  CG  . LYS   A 1 129 ? -11.11206 26.32760 -28.59898 1.000 65.66217  ? 126 LYS   A CG  1 
ATOM   1002 C  CD  . LYS   A 1 129 ? -11.71936 27.28701 -27.58598 1.000 89.34951  ? 126 LYS   A CD  1 
ATOM   1003 C  CE  . LYS   A 1 129 ? -13.02527 27.87981 -28.10269 1.000 91.53826  ? 126 LYS   A CE  1 
ATOM   1004 N  NZ  . LYS   A 1 129 ? -14.07096 26.83135 -28.29195 1.000 81.04619  ? 126 LYS   A NZ  1 
ATOM   1005 N  N   . PHE   A 1 130 ? -11.59918 25.44969 -32.03074 1.000 61.80315  ? 127 PHE   A N   1 
ATOM   1006 C  CA  . PHE   A 1 130 ? -12.67583 25.55048 -33.00480 1.000 60.70581  ? 127 PHE   A CA  1 
ATOM   1007 C  C   . PHE   A 1 130 ? -13.97618 25.98194 -32.33726 1.000 58.93836  ? 127 PHE   A C   1 
ATOM   1008 O  O   . PHE   A 1 130 ? -14.29989 25.54019 -31.23158 1.000 56.39936  ? 127 PHE   A O   1 
ATOM   1009 C  CB  . PHE   A 1 130 ? -12.87477 24.21599 -33.72174 1.000 62.15731  ? 127 PHE   A CB  1 
ATOM   1010 C  CG  . PHE   A 1 130 ? -11.74575 23.85101 -34.63935 1.000 60.17301  ? 127 PHE   A CG  1 
ATOM   1011 C  CD1 . PHE   A 1 130 ? -11.51237 24.58333 -35.79196 1.000 57.15474  ? 127 PHE   A CD1 1 
ATOM   1012 C  CD2 . PHE   A 1 130 ? -10.92417 22.77158 -34.35708 1.000 55.89371  ? 127 PHE   A CD2 1 
ATOM   1013 C  CE1 . PHE   A 1 130 ? -10.47540 24.25121 -36.64545 1.000 58.42532  ? 127 PHE   A CE1 1 
ATOM   1014 C  CE2 . PHE   A 1 130 ? -9.88539  22.43285 -35.20893 1.000 60.37341  ? 127 PHE   A CE2 1 
ATOM   1015 C  CZ  . PHE   A 1 130 ? -9.66021  23.17385 -36.35392 1.000 55.53276  ? 127 PHE   A CZ  1 
ATOM   1016 N  N   . ASN   A 1 131 ? -14.72519 26.84839 -33.02977 1.000 59.95156  ? 128 ASN   A N   1 
ATOM   1017 C  CA  . ASN   A 1 131 ? -15.99960 27.32097 -32.48791 1.000 57.25546  ? 128 ASN   A CA  1 
ATOM   1018 C  C   . ASN   A 1 131 ? -17.08430 26.24835 -32.50551 1.000 58.15667  ? 128 ASN   A C   1 
ATOM   1019 O  O   . ASN   A 1 131 ? -17.75499 26.06684 -31.47409 1.000 57.52919  ? 128 ASN   A O   1 
ATOM   1020 C  CB  . ASN   A 1 131 ? -16.44322 28.58442 -33.23266 1.000 59.89157  ? 128 ASN   A CB  1 
ATOM   1021 C  CG  . ASN   A 1 131 ? -15.45240 29.72114 -33.09283 1.000 62.94520  ? 128 ASN   A CG  1 
ATOM   1022 O  OD1 . ASN   A 1 131 ? -14.90946 29.95611 -32.01349 1.000 61.73500  ? 128 ASN   A OD1 1 
ATOM   1023 N  ND2 . ASN   A 1 131 ? -15.19834 30.42486 -34.19307 1.000 65.17800  ? 128 ASN   A ND2 1 
ATOM   1024 N  N   . PRO   A 1 132 ? -17.33530 25.53219 -33.60241 1.000 58.56637  ? 129 PRO   A N   1 
ATOM   1025 C  CA  . PRO   A 1 132 ? -18.38058 24.50486 -33.57674 1.000 57.97318  ? 129 PRO   A CA  1 
ATOM   1026 C  C   . PRO   A 1 132 ? -18.00608 23.37447 -32.63750 1.000 57.88747  ? 129 PRO   A C   1 
ATOM   1027 O  O   . PRO   A 1 132 ? -16.91007 22.80317 -32.74419 1.000 58.23573  ? 129 PRO   A O   1 
ATOM   1028 C  CB  . PRO   A 1 132 ? -18.44564 24.02127 -35.03491 1.000 50.96487  ? 129 PRO   A CB  1 
ATOM   1029 C  CG  . PRO   A 1 132 ? -17.85440 25.12613 -35.82419 1.000 56.68602  ? 129 PRO   A CG  1 
ATOM   1030 C  CD  . PRO   A 1 132 ? -16.77402 25.67905 -34.95675 1.000 53.82199  ? 129 PRO   A CD  1 
ATOM   1031 N  N   . PRO   A 1 133 ? -18.87722 23.04340 -31.68469 1.000 46.71581  ? 130 PRO   A N   1 
ATOM   1032 C  CA  . PRO   A 1 133 ? -18.61369 21.88074 -30.82304 1.000 46.68982  ? 130 PRO   A CA  1 
ATOM   1033 C  C   . PRO   A 1 133 ? -18.33397 20.60741 -31.59987 1.000 55.84892  ? 130 PRO   A C   1 
ATOM   1034 O  O   . PRO   A 1 133 ? -17.54183 19.77259 -31.14303 1.000 61.01195  ? 130 PRO   A O   1 
ATOM   1035 C  CB  . PRO   A 1 133 ? -19.89966 21.77057 -29.99344 1.000 44.09461  ? 130 PRO   A CB  1 
ATOM   1036 C  CG  . PRO   A 1 133 ? -20.43854 23.16944 -29.95801 1.000 39.17710  ? 130 PRO   A CG  1 
ATOM   1037 C  CD  . PRO   A 1 133 ? -20.10356 23.76208 -31.29765 1.000 51.49207  ? 130 PRO   A CD  1 
ATOM   1038 N  N   . ALA   A 1 134 ? -18.96339 20.43245 -32.76442 1.000 57.95165  ? 131 ALA   A N   1 
ATOM   1039 C  CA  . ALA   A 1 134 ? -18.69496 19.25840 -33.58944 1.000 55.38948  ? 131 ALA   A CA  1 
ATOM   1040 C  C   . ALA   A 1 134 ? -17.22880 19.19581 -33.99881 1.000 51.05671  ? 131 ALA   A C   1 
ATOM   1041 O  O   . ALA   A 1 134 ? -16.59663 18.13553 -33.92736 1.000 51.73689  ? 131 ALA   A O   1 
ATOM   1042 C  CB  . ALA   A 1 134 ? -19.59717 19.26880 -34.82237 1.000 50.40478  ? 131 ALA   A CB  1 
ATOM   1043 N  N   . LEU   A 1 135 ? -16.67185 20.32774 -34.43706 1.000 51.09353  ? 132 LEU   A N   1 
ATOM   1044 C  CA  . LEU   A 1 135 ? -15.27001 20.36156 -34.84253 1.000 49.79511  ? 132 LEU   A CA  1 
ATOM   1045 C  C   . LEU   A 1 135 ? -14.34187 20.14174 -33.65650 1.000 54.80228  ? 132 LEU   A C   1 
ATOM   1046 O  O   . LEU   A 1 135 ? -13.37912 19.37029 -33.74399 1.000 52.24893  ? 132 LEU   A O   1 
ATOM   1047 C  CB  . LEU   A 1 135 ? -14.94923 21.69292 -35.51636 1.000 50.27785  ? 132 LEU   A CB  1 
ATOM   1048 C  CG  . LEU   A 1 135 ? -14.80843 21.71394 -37.03154 1.000 55.55258  ? 132 LEU   A CG  1 
ATOM   1049 C  CD1 . LEU   A 1 135 ? -14.24183 23.05779 -37.45905 1.000 52.26197  ? 132 LEU   A CD1 1 
ATOM   1050 C  CD2 . LEU   A 1 135 ? -13.92131 20.56869 -37.49835 1.000 50.38756  ? 132 LEU   A CD2 1 
ATOM   1051 N  N   . GLN   A 1 136 ? -14.61230 20.81709 -32.53761 1.000 54.03284  ? 133 GLN   A N   1 
ATOM   1052 C  CA  . GLN   A 1 136 ? -13.73002 20.69708 -31.38240 1.000 57.68757  ? 133 GLN   A CA  1 
ATOM   1053 C  C   . GLN   A 1 136 ? -13.71966 19.27153 -30.84614 1.000 53.65856  ? 133 GLN   A C   1 
ATOM   1054 O  O   . GLN   A 1 136 ? -12.65328 18.72720 -30.53552 1.000 51.32891  ? 133 GLN   A O   1 
ATOM   1055 C  CB  . GLN   A 1 136 ? -14.14926 21.68444 -30.29430 1.000 54.72804  ? 133 GLN   A CB  1 
ATOM   1056 C  CG  . GLN   A 1 136 ? -13.09493 21.90275 -29.22257 1.000 59.01654  ? 133 GLN   A CG  1 
ATOM   1057 C  CD  . GLN   A 1 136 ? -11.74026 22.28346 -29.79764 1.000 65.00195  ? 133 GLN   A CD  1 
ATOM   1058 O  OE1 . GLN   A 1 136 ? -11.64365 23.13667 -30.68196 1.000 68.44037  ? 133 GLN   A OE1 1 
ATOM   1059 N  NE2 . GLN   A 1 136 ? -10.68562 21.65511 -29.29213 1.000 66.46641  ? 133 GLN   A NE2 1 
ATOM   1060 N  N   . ASP   A 1 137 ? -14.89547 18.64689 -30.74168 1.000 48.39290  ? 134 ASP   A N   1 
ATOM   1061 C  CA  . ASP   A 1 137 ? -14.95872 17.25859 -30.29388 1.000 51.67811  ? 134 ASP   A CA  1 
ATOM   1062 C  C   . ASP   A 1 137 ? -14.16861 16.34845 -31.22710 1.000 56.59741  ? 134 ASP   A C   1 
ATOM   1063 O  O   . ASP   A 1 137 ? -13.38525 15.50471 -30.77563 1.000 55.40363  ? 134 ASP   A O   1 
ATOM   1064 C  CB  . ASP   A 1 137 ? -16.41676 16.80204 -30.20565 1.000 59.89011  ? 134 ASP   A CB  1 
ATOM   1065 C  CG  . ASP   A 1 137 ? -17.17334 17.46400 -29.06691 1.000 71.22513  ? 134 ASP   A CG  1 
ATOM   1066 O  OD1 . ASP   A 1 137 ? -16.56465 18.25303 -28.31299 1.000 74.01403  ? 134 ASP   A OD1 1 
ATOM   1067 O  OD2 . ASP   A 1 137 ? -18.38632 17.19523 -28.93130 1.000 74.66181  ? 134 ASP   A OD2 1 
ATOM   1068 N  N   . ALA   A 1 138 ? -14.35371 16.51621 -32.53977 1.000 57.49454  ? 135 ALA   A N   1 
ATOM   1069 C  CA  . ALA   A 1 138 ? -13.63599 15.68864 -33.50322 1.000 46.05394  ? 135 ALA   A CA  1 
ATOM   1070 C  C   . ALA   A 1 138 ? -12.14667 16.00670 -33.51479 1.000 51.85526  ? 135 ALA   A C   1 
ATOM   1071 O  O   . ALA   A 1 138 ? -11.32583 15.11074 -33.74318 1.000 51.30495  ? 135 ALA   A O   1 
ATOM   1072 C  CB  . ALA   A 1 138 ? -14.23290 15.86852 -34.89704 1.000 50.62573  ? 135 ALA   A CB  1 
ATOM   1073 N  N   . TYR   A 1 139 ? -11.78717 17.27503 -33.29437 1.000 51.85412  ? 136 TYR   A N   1 
ATOM   1074 C  CA  . TYR   A 1 139 ? -10.38598 17.65909 -33.14336 1.000 47.53980  ? 136 TYR   A CA  1 
ATOM   1075 C  C   . TYR   A 1 139 ? -9.71303  16.84752 -32.04352 1.000 54.50884  ? 136 TYR   A C   1 
ATOM   1076 O  O   . TYR   A 1 139 ? -8.63261  16.27997 -32.24134 1.000 52.22436  ? 136 TYR   A O   1 
ATOM   1077 C  CB  . TYR   A 1 139 ? -10.30170 19.15451 -32.83170 1.000 58.56845  ? 136 TYR   A CB  1 
ATOM   1078 C  CG  . TYR   A 1 139 ? -8.92676  19.77896 -32.95221 1.000 62.59984  ? 136 TYR   A CG  1 
ATOM   1079 C  CD1 . TYR   A 1 139 ? -7.87735  19.11481 -33.57661 1.000 59.78051  ? 136 TYR   A CD1 1 
ATOM   1080 C  CD2 . TYR   A 1 139 ? -8.67635  21.03632 -32.41333 1.000 69.17497  ? 136 TYR   A CD2 1 
ATOM   1081 C  CE1 . TYR   A 1 139 ? -6.61796  19.69940 -33.67640 1.000 58.70139  ? 136 TYR   A CE1 1 
ATOM   1082 C  CE2 . TYR   A 1 139 ? -7.43073  21.62493 -32.50746 1.000 67.80011  ? 136 TYR   A CE2 1 
ATOM   1083 C  CZ  . TYR   A 1 139 ? -6.40513  20.95725 -33.13561 1.000 69.33217  ? 136 TYR   A CZ  1 
ATOM   1084 O  OH  . TYR   A 1 139 ? -5.17156  21.56393 -33.21273 1.000 69.90393  ? 136 TYR   A OH  1 
ATOM   1085 N  N   . TYR   A 1 140 ? -10.34675 16.78683 -30.87046 1.000 53.10210  ? 137 TYR   A N   1 
ATOM   1086 C  CA  . TYR   A 1 140 ? -9.79619  16.02402 -29.75451 1.000 49.99908  ? 137 TYR   A CA  1 
ATOM   1087 C  C   . TYR   A 1 140 ? -9.65006  14.54978 -30.11235 1.000 56.11327  ? 137 TYR   A C   1 
ATOM   1088 O  O   . TYR   A 1 140 ? -8.57731  13.95930 -29.93791 1.000 60.28584  ? 137 TYR   A O   1 
ATOM   1089 C  CB  . TYR   A 1 140 ? -10.68387 16.19570 -28.52396 1.000 49.42356  ? 137 TYR   A CB  1 
ATOM   1090 C  CG  . TYR   A 1 140 ? -10.48870 17.50869 -27.80117 1.000 56.79529  ? 137 TYR   A CG  1 
ATOM   1091 C  CD1 . TYR   A 1 140 ? -9.22123  17.93754 -27.42699 1.000 59.11430  ? 137 TYR   A CD1 1 
ATOM   1092 C  CD2 . TYR   A 1 140 ? -11.57204 18.32582 -27.49845 1.000 53.40002  ? 137 TYR   A CD2 1 
ATOM   1093 C  CE1 . TYR   A 1 140 ? -9.03802  19.13997 -26.76013 1.000 52.32152  ? 137 TYR   A CE1 1 
ATOM   1094 C  CE2 . TYR   A 1 140 ? -11.39814 19.53069 -26.83529 1.000 53.62406  ? 137 TYR   A CE2 1 
ATOM   1095 C  CZ  . TYR   A 1 140 ? -10.12922 19.93260 -26.46845 1.000 59.40630  ? 137 TYR   A CZ  1 
ATOM   1096 O  OH  . TYR   A 1 140 ? -9.94857  21.12910 -25.80855 1.000 59.01422  ? 137 TYR   A OH  1 
ATOM   1097 N  N   . ARG   A 1 141 ? -10.72421 13.93442 -30.61088 1.000 49.56695  ? 138 ARG   A N   1 
ATOM   1098 C  CA  . ARG   A 1 141 ? -10.65864 12.51722 -30.94240 1.000 51.54982  ? 138 ARG   A CA  1 
ATOM   1099 C  C   . ARG   A 1 141 ? -9.64491  12.24866 -32.04523 1.000 57.89142  ? 138 ARG   A C   1 
ATOM   1100 O  O   . ARG   A 1 141 ? -9.11265  11.13665 -32.14206 1.000 55.45351  ? 138 ARG   A O   1 
ATOM   1101 C  CB  . ARG   A 1 141 ? -12.03592 12.00142 -31.35609 1.000 53.16671  ? 138 ARG   A CB  1 
ATOM   1102 C  CG  . ARG   A 1 141 ? -13.06615 12.00237 -30.23869 1.000 53.87670  ? 138 ARG   A CG  1 
ATOM   1103 C  CD  . ARG   A 1 141 ? -14.40722 11.49603 -30.74374 1.000 61.08321  ? 138 ARG   A CD  1 
ATOM   1104 N  NE  . ARG   A 1 141 ? -14.26281 10.20595 -31.41085 1.000 81.95589  ? 138 ARG   A NE  1 
ATOM   1105 C  CZ  . ARG   A 1 141 ? -15.12781 9.70031  -32.28082 1.000 86.81594  ? 138 ARG   A CZ  1 
ATOM   1106 N  NH1 . ARG   A 1 141 ? -16.21899 10.36054 -32.63663 1.000 79.85737  ? 138 ARG   A NH1 1 
ATOM   1107 N  NH2 . ARG   A 1 141 ? -14.88974 8.50256  -32.81052 1.000 79.24284  ? 138 ARG   A NH2 1 
ATOM   1108 N  N   . ALA   A 1 142 ? -9.36449  13.24916 -32.88305 1.000 59.22356  ? 139 ALA   A N   1 
ATOM   1109 C  CA  . ALA   A 1 142 ? -8.35236  13.07964 -33.91883 1.000 52.65992  ? 139 ALA   A CA  1 
ATOM   1110 C  C   . ALA   A 1 142 ? -6.95578  12.98024 -33.31617 1.000 51.42314  ? 139 ALA   A C   1 
ATOM   1111 O  O   . ALA   A 1 142 ? -6.12938  12.18812 -33.78422 1.000 51.44532  ? 139 ALA   A O   1 
ATOM   1112 C  CB  . ALA   A 1 142 ? -8.43026  14.22655 -34.92526 1.000 49.47742  ? 139 ALA   A CB  1 
ATOM   1113 N  N   . ARG   A 1 143 ? -6.67014  13.77346 -32.27739 1.000 59.55270  ? 140 ARG   A N   1 
ATOM   1114 C  CA  . ARG   A 1 143 ? -5.36567  13.67935 -31.62599 1.000 58.21857  ? 140 ARG   A CA  1 
ATOM   1115 C  C   . ARG   A 1 143 ? -5.16381  12.32028 -30.97598 1.000 51.67302  ? 140 ARG   A C   1 
ATOM   1116 O  O   . ARG   A 1 143 ? -4.03026  11.83368 -30.89559 1.000 57.94784  ? 140 ARG   A O   1 
ATOM   1117 C  CB  . ARG   A 1 143 ? -5.20663  14.78301 -30.58175 1.000 48.14134  ? 140 ARG   A CB  1 
ATOM   1118 C  CG  . ARG   A 1 143 ? -4.87563  16.14531 -31.15479 1.000 63.52096  ? 140 ARG   A CG  1 
ATOM   1119 C  CD  . ARG   A 1 143 ? -4.59996  17.14627 -30.04572 1.000 69.21155  ? 140 ARG   A CD  1 
ATOM   1120 N  NE  . ARG   A 1 143 ? -4.17891  18.44165 -30.56543 1.000 72.94889  ? 140 ARG   A NE  1 
ATOM   1121 C  CZ  . ARG   A 1 143 ? -2.92303  18.76150 -30.84704 1.000 73.17829  ? 140 ARG   A CZ  1 
ATOM   1122 N  NH1 . ARG   A 1 143 ? -1.93316  17.89956 -30.66688 1.000 64.39297  ? 140 ARG   A NH1 1 
ATOM   1123 N  NH2 . ARG   A 1 143 ? -2.65259  19.97755 -31.31689 1.000 70.06555  ? 140 ARG   A NH2 1 
ATOM   1124 N  N   . ALA   A 1 144 ? -6.24561  11.68587 -30.53060 1.000 51.54017  ? 141 ALA   A N   1 
ATOM   1125 C  CA  . ALA   A 1 144 ? -6.17036  10.35893 -29.93720 1.000 54.43357  ? 141 ALA   A CA  1 
ATOM   1126 C  C   . ALA   A 1 144 ? -6.11856  9.24261  -30.97135 1.000 60.60533  ? 141 ALA   A C   1 
ATOM   1127 O  O   . ALA   A 1 144 ? -5.98319  8.07643  -30.58725 1.000 69.32650  ? 141 ALA   A O   1 
ATOM   1128 C  CB  . ALA   A 1 144 ? -7.36131  10.13439 -29.00387 1.000 59.05305  ? 141 ALA   A CB  1 
ATOM   1129 N  N   . GLY   A 1 145 ? -6.23693  9.55945  -32.26050 1.000 59.16079  ? 142 GLY   A N   1 
ATOM   1130 C  CA  . GLY   A 1 145 ? -6.13379  8.56683  -33.31212 1.000 53.88323  ? 142 GLY   A CA  1 
ATOM   1131 C  C   . GLY   A 1 145 ? -7.43540  8.22304  -34.00322 1.000 62.19470  ? 142 GLY   A C   1 
ATOM   1132 O  O   . GLY   A 1 145 ? -7.42044  7.41657  -34.94254 1.000 56.32480  ? 142 GLY   A O   1 
ATOM   1133 N  N   . GLU   A 1 146 ? -8.55579  8.79472  -33.57148 1.000 64.49832  ? 143 GLU   A N   1 
ATOM   1134 C  CA  . GLU   A 1 146 ? -9.86065  8.55461  -34.18094 1.000 60.45629  ? 143 GLU   A CA  1 
ATOM   1135 C  C   . GLU   A 1 146 ? -10.25537 9.78506  -34.99268 1.000 58.83413  ? 143 GLU   A C   1 
ATOM   1136 O  O   . GLU   A 1 146 ? -11.13039 10.56770 -34.61021 1.000 60.00977  ? 143 GLU   A O   1 
ATOM   1137 C  CB  . GLU   A 1 146 ? -10.89111 8.23665  -33.09487 1.000 60.85451  ? 143 GLU   A CB  1 
ATOM   1138 C  CG  . GLU   A 1 146 ? -10.65335 6.91061  -32.39010 1.000 78.21575  ? 143 GLU   A CG  1 
ATOM   1139 C  CD  . GLU   A 1 146 ? -11.12899 6.92089  -30.94556 1.000 110.40801 ? 143 GLU   A CD  1 
ATOM   1140 O  OE1 . GLU   A 1 146 ? -11.81074 7.88956  -30.54406 1.000 103.56648 ? 143 GLU   A OE1 1 
ATOM   1141 O  OE2 . GLU   A 1 146 ? -10.81597 5.96168  -30.20819 1.000 116.52530 ? 143 GLU   A OE2 1 
ATOM   1142 N  N   . ALA   A 1 147 ? -9.59460  9.94569  -36.13666 1.000 54.85406  ? 144 ALA   A N   1 
ATOM   1143 C  CA  . ALA   A 1 147 ? -9.68879  11.16099 -36.93115 1.000 59.17540  ? 144 ALA   A CA  1 
ATOM   1144 C  C   . ALA   A 1 147 ? -10.74304 11.08596 -38.02851 1.000 52.63052  ? 144 ALA   A C   1 
ATOM   1145 O  O   . ALA   A 1 147 ? -10.84182 12.01662 -38.83357 1.000 53.66246  ? 144 ALA   A O   1 
ATOM   1146 C  CB  . ALA   A 1 147 ? -8.32555  11.48438 -37.54685 1.000 52.09076  ? 144 ALA   A CB  1 
ATOM   1147 N  N   . ALA   A 1 148 ? -11.53608 10.01412 -38.07631 1.000 49.56241  ? 145 ALA   A N   1 
ATOM   1148 C  CA  . ALA   A 1 148 ? -12.50189 9.86148  -39.16011 1.000 49.70901  ? 145 ALA   A CA  1 
ATOM   1149 C  C   . ALA   A 1 148 ? -13.52080 10.99712 -39.15694 1.000 50.29620  ? 145 ALA   A C   1 
ATOM   1150 O  O   . ALA   A 1 148 ? -13.74590 11.64232 -40.18671 1.000 55.09503  ? 145 ALA   A O   1 
ATOM   1151 C  CB  . ALA   A 1 148 ? -13.19387 8.50249  -39.06527 1.000 47.81220  ? 145 ALA   A CB  1 
ATOM   1152 N  N   . ASN   A 1 149 ? -14.15163 11.25695 -38.00721 1.000 49.13571  ? 146 ASN   A N   1 
ATOM   1153 C  CA  . ASN   A 1 149 ? -15.14329 12.32914 -37.94307 1.000 51.29426  ? 146 ASN   A CA  1 
ATOM   1154 C  C   . ASN   A 1 149 ? -14.51729 13.68091 -38.25435 1.000 51.47903  ? 146 ASN   A C   1 
ATOM   1155 O  O   . ASN   A 1 149 ? -15.13981 14.52575 -38.90989 1.000 51.44048  ? 146 ASN   A O   1 
ATOM   1156 C  CB  . ASN   A 1 149 ? -15.80565 12.36083 -36.56598 1.000 48.03189  ? 146 ASN   A CB  1 
ATOM   1157 C  CG  . ASN   A 1 149 ? -16.68631 11.15792 -36.31829 1.000 62.82613  ? 146 ASN   A CG  1 
ATOM   1158 O  OD1 . ASN   A 1 149 ? -16.20332 10.09246 -35.93766 1.000 70.60315  ? 146 ASN   A OD1 1 
ATOM   1159 N  ND2 . ASN   A 1 149 ? -17.98923 11.32324 -36.52192 1.000 62.45551  ? 146 ASN   A ND2 1 
ATOM   1160 N  N   . PHE   A 1 150 ? -13.27993 13.89820 -37.80693 1.000 49.99725  ? 147 PHE   A N   1 
ATOM   1161 C  CA  . PHE   A 1 150 ? -12.61949 15.17414 -38.05746 1.000 49.05968  ? 147 PHE   A CA  1 
ATOM   1162 C  C   . PHE   A 1 150 ? -12.39017 15.39142 -39.54862 1.000 56.63462  ? 147 PHE   A C   1 
ATOM   1163 O  O   . PHE   A 1 150 ? -12.70171 16.46066 -40.08692 1.000 48.93212  ? 147 PHE   A O   1 
ATOM   1164 C  CB  . PHE   A 1 150 ? -11.30329 15.23623 -37.28525 1.000 43.99771  ? 147 PHE   A CB  1 
ATOM   1165 C  CG  . PHE   A 1 150 ? -10.67536 16.59535 -37.26997 1.000 44.57914  ? 147 PHE   A CG  1 
ATOM   1166 C  CD1 . PHE   A 1 150 ? -11.39469 17.70063 -36.84569 1.000 44.82697  ? 147 PHE   A CD1 1 
ATOM   1167 C  CD2 . PHE   A 1 150 ? -9.36060  16.76860 -37.66633 1.000 49.04502  ? 147 PHE   A CD2 1 
ATOM   1168 C  CE1 . PHE   A 1 150 ? -10.81476 18.95909 -36.82846 1.000 45.30044  ? 147 PHE   A CE1 1 
ATOM   1169 C  CE2 . PHE   A 1 150 ? -8.77409  18.02167 -37.64811 1.000 46.94940  ? 147 PHE   A CE2 1 
ATOM   1170 C  CZ  . PHE   A 1 150 ? -9.50278  19.11880 -37.22977 1.000 40.41014  ? 147 PHE   A CZ  1 
ATOM   1171 N  N   . CYS   A 1 151 ? -11.85475 14.38175 -40.23704 1.000 48.78782  ? 148 CYS   A N   1 
ATOM   1172 C  CA  . CYS   A 1 151 ? -11.63829 14.51113 -41.67444 1.000 50.85371  ? 148 CYS   A CA  1 
ATOM   1173 C  C   . CYS   A 1 151 ? -12.95736 14.69645 -42.41648 1.000 54.63546  ? 148 CYS   A C   1 
ATOM   1174 O  O   . CYS   A 1 151 ? -13.04357 15.49906 -43.35428 1.000 51.65648  ? 148 CYS   A O   1 
ATOM   1175 C  CB  . CYS   A 1 151 ? -10.87973 13.29510 -42.20559 1.000 50.77321  ? 148 CYS   A CB  1 
ATOM   1176 S  SG  . CYS   A 1 151 ? -9.22618  13.09408 -41.49340 1.000 51.76079  ? 148 CYS   A SG  1 
ATOM   1177 N  N   . ALA   A 1 152 ? -13.99789 13.96250 -42.01017 1.000 51.49623  ? 149 ALA   A N   1 
ATOM   1178 C  CA  . ALA   A 1 152 ? -15.30128 14.10646 -42.65138 1.000 43.22197  ? 149 ALA   A CA  1 
ATOM   1179 C  C   . ALA   A 1 152 ? -15.86283 15.50821 -42.45043 1.000 46.16445  ? 149 ALA   A C   1 
ATOM   1180 O  O   . ALA   A 1 152 ? -16.44315 16.08980 -43.37445 1.000 46.62176  ? 149 ALA   A O   1 
ATOM   1181 C  CB  . ALA   A 1 152 ? -16.27140 13.05438 -42.11576 1.000 41.81446  ? 149 ALA   A CB  1 
ATOM   1182 N  N   . LEU   A 1 153 ? -15.70958 16.06456 -41.24547 1.000 49.78396  ? 150 LEU   A N   1 
ATOM   1183 C  CA  . LEU   A 1 153 ? -16.18344 17.42281 -41.00158 1.000 43.30430  ? 150 LEU   A CA  1 
ATOM   1184 C  C   . LEU   A 1 153 ? -15.37279 18.44094 -41.79518 1.000 49.59202  ? 150 LEU   A C   1 
ATOM   1185 O  O   . LEU   A 1 153 ? -15.92772 19.42597 -42.29588 1.000 47.80669  ? 150 LEU   A O   1 
ATOM   1186 C  CB  . LEU   A 1 153 ? -16.12933 17.74171 -39.50759 1.000 50.56334  ? 150 LEU   A CB  1 
ATOM   1187 C  CG  . LEU   A 1 153 ? -17.19308 17.09987 -38.61498 1.000 57.03272  ? 150 LEU   A CG  1 
ATOM   1188 C  CD1 . LEU   A 1 153 ? -16.86395 17.35099 -37.15794 1.000 51.44155  ? 150 LEU   A CD1 1 
ATOM   1189 C  CD2 . LEU   A 1 153 ? -18.58226 17.63359 -38.94552 1.000 49.62744  ? 150 LEU   A CD2 1 
ATOM   1190 N  N   . ILE   A 1 154 ? -14.05963 18.21952 -41.92434 1.000 49.44689  ? 151 ILE   A N   1 
ATOM   1191 C  CA  . ILE   A 1 154 ? -13.22486 19.11748 -42.72059 1.000 47.81039  ? 151 ILE   A CA  1 
ATOM   1192 C  C   . ILE   A 1 154 ? -13.71959 19.16545 -44.15902 1.000 50.02941  ? 151 ILE   A C   1 
ATOM   1193 O  O   . ILE   A 1 154 ? -13.83977 20.24288 -44.75561 1.000 47.89123  ? 151 ILE   A O   1 
ATOM   1194 C  CB  . ILE   A 1 154 ? -11.74662 18.68851 -42.64371 1.000 54.54980  ? 151 ILE   A CB  1 
ATOM   1195 C  CG1 . ILE   A 1 154 ? -11.17301 18.98032 -41.25435 1.000 59.38581  ? 151 ILE   A CG1 1 
ATOM   1196 C  CG2 . ILE   A 1 154 ? -10.92160 19.39108 -43.71562 1.000 43.33016  ? 151 ILE   A CG2 1 
ATOM   1197 C  CD1 . ILE   A 1 154 ? -9.75830  18.47781 -41.06060 1.000 50.04956  ? 151 ILE   A CD1 1 
ATOM   1198 N  N   . LEU   A 1 155 ? -14.02638 17.99991 -44.73470 1.000 46.83524  ? 152 LEU   A N   1 
ATOM   1199 C  CA  . LEU   A 1 155 ? -14.54971 17.96281 -46.09689 1.000 45.87655  ? 152 LEU   A CA  1 
ATOM   1200 C  C   . LEU   A 1 155 ? -15.88500 18.68981 -46.19285 1.000 50.52094  ? 152 LEU   A C   1 
ATOM   1201 O  O   . LEU   A 1 155 ? -16.12801 19.43237 -47.15176 1.000 45.67327  ? 152 LEU   A O   1 
ATOM   1202 C  CB  . LEU   A 1 155 ? -14.68607 16.51385 -46.56270 1.000 40.39289  ? 152 LEU   A CB  1 
ATOM   1203 C  CG  . LEU   A 1 155 ? -13.36694 15.77245 -46.78192 1.000 44.38561  ? 152 LEU   A CG  1 
ATOM   1204 C  CD1 . LEU   A 1 155 ? -13.60305 14.29068 -46.99946 1.000 35.20913  ? 152 LEU   A CD1 1 
ATOM   1205 C  CD2 . LEU   A 1 155 ? -12.62621 16.36578 -47.96749 1.000 48.91473  ? 152 LEU   A CD2 1 
ATOM   1206 N  N   . ALA   A 1 156 ? -16.76154 18.49204 -45.20645 1.000 43.61233  ? 153 ALA   A N   1 
ATOM   1207 C  CA  . ALA   A 1 156 ? -18.07331 19.12794 -45.24425 1.000 39.57144  ? 153 ALA   A CA  1 
ATOM   1208 C  C   . ALA   A 1 156 ? -17.95778 20.64484 -45.12891 1.000 46.99033  ? 153 ALA   A C   1 
ATOM   1209 O  O   . ALA   A 1 156 ? -18.59489 21.38431 -45.88767 1.000 55.14863  ? 153 ALA   A O   1 
ATOM   1210 C  CB  . ALA   A 1 156 ? -18.96592 18.56215 -44.14089 1.000 47.32162  ? 153 ALA   A CB  1 
ATOM   1211 N  N   . TYR   A 1 157 ? -17.14814 21.13251 -44.18677 1.000 45.95131  ? 154 TYR   A N   1 
ATOM   1212 C  CA  . TYR   A 1 157 ? -17.01763 22.57635 -44.02150 1.000 50.72315  ? 154 TYR   A CA  1 
ATOM   1213 C  C   . TYR   A 1 157 ? -16.35528 23.24301 -45.22217 1.000 56.42452  ? 154 TYR   A C   1 
ATOM   1214 O  O   . TYR   A 1 157 ? -16.53201 24.45072 -45.42016 1.000 54.51463  ? 154 TYR   A O   1 
ATOM   1215 C  CB  . TYR   A 1 157 ? -16.23780 22.90116 -42.74521 1.000 45.57901  ? 154 TYR   A CB  1 
ATOM   1216 C  CG  . TYR   A 1 157 ? -17.06090 22.79229 -41.47728 1.000 52.11332  ? 154 TYR   A CG  1 
ATOM   1217 C  CD1 . TYR   A 1 157 ? -18.02249 23.74532 -41.16678 1.000 49.30778  ? 154 TYR   A CD1 1 
ATOM   1218 C  CD2 . TYR   A 1 157 ? -16.87010 21.74246 -40.58704 1.000 48.60169  ? 154 TYR   A CD2 1 
ATOM   1219 C  CE1 . TYR   A 1 157 ? -18.77655 23.65196 -40.00993 1.000 47.33412  ? 154 TYR   A CE1 1 
ATOM   1220 C  CE2 . TYR   A 1 157 ? -17.62035 21.63951 -39.42623 1.000 45.97274  ? 154 TYR   A CE2 1 
ATOM   1221 C  CZ  . TYR   A 1 157 ? -18.57167 22.59748 -39.14402 1.000 49.30378  ? 154 TYR   A CZ  1 
ATOM   1222 O  OH  . TYR   A 1 157 ? -19.32205 22.50320 -37.99397 1.000 49.34191  ? 154 TYR   A OH  1 
ATOM   1223 N  N   . CYS   A 1 158 ? -15.60659 22.49085 -46.02559 1.000 52.51034  ? 155 CYS   A N   1 
ATOM   1224 C  CA  . CYS   A 1 158 ? -14.90697 23.03616 -47.17967 1.000 53.72527  ? 155 CYS   A CA  1 
ATOM   1225 C  C   . CYS   A 1 158 ? -15.64880 22.80439 -48.48976 1.000 56.62168  ? 155 CYS   A C   1 
ATOM   1226 O  O   . CYS   A 1 158 ? -15.15680 23.22077 -49.54317 1.000 56.43386  ? 155 CYS   A O   1 
ATOM   1227 C  CB  . CYS   A 1 158 ? -13.50059 22.43140 -47.27466 1.000 49.66384  ? 155 CYS   A CB  1 
ATOM   1228 S  SG  . CYS   A 1 158 ? -12.38040 22.88487 -45.92210 1.000 56.72633  ? 155 CYS   A SG  1 
ATOM   1229 N  N   . ASN   A 1 159 ? -16.81626 22.15910 -48.44768 1.000 55.05439  ? 156 ASN   A N   1 
ATOM   1230 C  CA  . ASN   A 1 159 ? -17.57180 21.80076 -49.65114 1.000 59.48173  ? 156 ASN   A CA  1 
ATOM   1231 C  C   . ASN   A 1 159 ? -16.72098 20.98528 -50.62200 1.000 60.14419  ? 156 ASN   A C   1 
ATOM   1232 O  O   . ASN   A 1 159 ? -16.72547 21.21197 -51.83539 1.000 63.92977  ? 156 ASN   A O   1 
ATOM   1233 C  CB  . ASN   A 1 159 ? -18.15618 23.03658 -50.33416 1.000 56.15830  ? 156 ASN   A CB  1 
ATOM   1234 C  CG  . ASN   A 1 159 ? -19.34275 23.60290 -49.58442 1.000 80.43932  ? 156 ASN   A CG  1 
ATOM   1235 O  OD1 . ASN   A 1 159 ? -19.18829 24.35487 -48.61974 1.000 78.48068  ? 156 ASN   A OD1 1 
ATOM   1236 N  ND2 . ASN   A 1 159 ? -20.54327 23.23363 -50.02122 1.000 79.46561  ? 156 ASN   A ND2 1 
ATOM   1237 N  N   . LYS   A 1 160 ? -15.98108 20.02290 -50.07811 1.000 44.39137  ? 157 LYS   A N   1 
ATOM   1238 C  CA  . LYS   A 1 160 ? -15.24341 19.05996 -50.87584 1.000 49.67972  ? 157 LYS   A CA  1 
ATOM   1239 C  C   . LYS   A 1 160 ? -15.74633 17.65844 -50.55915 1.000 50.63880  ? 157 LYS   A C   1 
ATOM   1240 O  O   . LYS   A 1 160 ? -16.30467 17.40349 -49.48863 1.000 50.38178  ? 157 LYS   A O   1 
ATOM   1241 C  CB  . LYS   A 1 160 ? -13.73638 19.16771 -50.62173 1.000 46.27759  ? 157 LYS   A CB  1 
ATOM   1242 C  CG  . LYS   A 1 160 ? -13.18470 20.54674 -50.94316 1.000 54.94927  ? 157 LYS   A CG  1 
ATOM   1243 C  CD  . LYS   A 1 160 ? -11.73339 20.49233 -51.35844 1.000 57.21404  ? 157 LYS   A CD  1 
ATOM   1244 C  CE  . LYS   A 1 160 ? -11.61252 19.99816 -52.78005 1.000 58.95511  ? 157 LYS   A CE  1 
ATOM   1245 N  NZ  . LYS   A 1 160 ? -12.38493 20.86379 -53.71260 1.000 76.16288  ? 157 LYS   A NZ  1 
ATOM   1246 N  N   . THR   A 1 161 ? -15.56499 16.74994 -51.51214 1.000 55.25780  ? 158 THR   A N   1 
ATOM   1247 C  CA  . THR   A 1 161 ? -16.00000 15.37263 -51.35028 1.000 52.62854  ? 158 THR   A CA  1 
ATOM   1248 C  C   . THR   A 1 161 ? -14.79628 14.44062 -51.40251 1.000 52.76579  ? 158 THR   A C   1 
ATOM   1249 O  O   . THR   A 1 161 ? -13.72192 14.80061 -51.89333 1.000 52.85590  ? 158 THR   A O   1 
ATOM   1250 C  CB  . THR   A 1 161 ? -17.02228 14.96861 -52.42353 1.000 49.10523  ? 158 THR   A CB  1 
ATOM   1251 O  OG1 . THR   A 1 161 ? -16.38383 14.92293 -53.70259 1.000 63.08688  ? 158 THR   A OG1 1 
ATOM   1252 C  CG2 . THR   A 1 161 ? -18.17046 15.96458 -52.47228 1.000 48.09974  ? 158 THR   A CG2 1 
ATOM   1253 N  N   . VAL   A 1 162 ? -14.99598 13.22869 -50.88205 1.000 46.91797  ? 159 VAL   A N   1 
ATOM   1254 C  CA  . VAL   A 1 162 ? -13.94332 12.22257 -50.89388 1.000 51.03054  ? 159 VAL   A CA  1 
ATOM   1255 C  C   . VAL   A 1 162 ? -13.52151 11.94558 -52.32896 1.000 58.12080  ? 159 VAL   A C   1 
ATOM   1256 O  O   . VAL   A 1 162 ? -14.36225 11.72582 -53.20995 1.000 48.32197  ? 159 VAL   A O   1 
ATOM   1257 C  CB  . VAL   A 1 162 ? -14.42850 10.94679 -50.19077 1.000 44.03702  ? 159 VAL   A CB  1 
ATOM   1258 C  CG1 . VAL   A 1 162 ? -13.38644 9.84510  -50.28724 1.000 47.72785  ? 159 VAL   A CG1 1 
ATOM   1259 C  CG2 . VAL   A 1 162 ? -14.75584 11.24453 -48.74562 1.000 49.04074  ? 159 VAL   A CG2 1 
ATOM   1260 N  N   . GLY   A 1 163 ? -12.21034 11.97105 -52.57259 1.000 52.54118  ? 160 GLY   A N   1 
ATOM   1261 C  CA  . GLY   A 1 163 ? -11.67050 11.72998 -53.89923 1.000 49.49279  ? 160 GLY   A CA  1 
ATOM   1262 C  C   . GLY   A 1 163 ? -11.14558 12.96660 -54.60175 1.000 52.71045  ? 160 GLY   A C   1 
ATOM   1263 O  O   . GLY   A 1 163 ? -10.14231 12.90039 -55.31895 1.000 54.46519  ? 160 GLY   A O   1 
ATOM   1264 N  N   . GLU   A 1 164 ? -11.82222 14.09630 -54.41035 1.000 48.45739  ? 161 GLU   A N   1 
ATOM   1265 C  CA  . GLU   A 1 164 ? -11.40630 15.34483 -55.03525 1.000 45.57191  ? 161 GLU   A CA  1 
ATOM   1266 C  C   . GLU   A 1 164 ? -10.02678 15.77162 -54.54775 1.000 50.80422  ? 161 GLU   A C   1 
ATOM   1267 O  O   . GLU   A 1 164 ? -9.69429  15.62920 -53.36774 1.000 61.58326  ? 161 GLU   A O   1 
ATOM   1268 C  CB  . GLU   A 1 164 ? -12.41040 16.45699 -54.72964 1.000 46.04719  ? 161 GLU   A CB  1 
ATOM   1269 C  CG  . GLU   A 1 164 ? -13.81952 16.22581 -55.22622 1.000 50.78536  ? 161 GLU   A CG  1 
ATOM   1270 C  CD  . GLU   A 1 164 ? -14.67369 17.47298 -55.08839 1.000 66.64806  ? 161 GLU   A CD  1 
ATOM   1271 O  OE1 . GLU   A 1 164 ? -14.09597 18.57517 -54.98529 1.000 74.43880  ? 161 GLU   A OE1 1 
ATOM   1272 O  OE2 . GLU   A 1 164 ? -15.91681 17.35871 -55.07433 1.000 76.22172  ? 161 GLU   A OE2 1 
ATOM   1273 N  N   . LEU   A 1 165 ? -9.21645  16.28996 -55.46628 1.000 53.38580  ? 162 LEU   A N   1 
ATOM   1274 C  CA  . LEU   A 1 165 ? -7.95214  16.89000 -55.07095 1.000 58.07667  ? 162 LEU   A CA  1 
ATOM   1275 C  C   . LEU   A 1 165 ? -8.22243  18.19722 -54.32981 1.000 50.92462  ? 162 LEU   A C   1 
ATOM   1276 O  O   . LEU   A 1 165 ? -9.29560  18.79426 -54.44861 1.000 49.10862  ? 162 LEU   A O   1 
ATOM   1277 C  CB  . LEU   A 1 165 ? -7.06590  17.15313 -56.29087 1.000 57.98356  ? 162 LEU   A CB  1 
ATOM   1278 C  CG  . LEU   A 1 165 ? -6.78617  16.00021 -57.25994 1.000 57.35596  ? 162 LEU   A CG  1 
ATOM   1279 C  CD1 . LEU   A 1 165 ? -5.72685  16.40787 -58.26112 1.000 63.88341  ? 162 LEU   A CD1 1 
ATOM   1280 C  CD2 . LEU   A 1 165 ? -6.34768  14.75597 -56.52036 1.000 64.16883  ? 162 LEU   A CD2 1 
ATOM   1281 N  N   . GLY   A 1 166 ? -7.23918  18.64267 -53.55108 1.000 51.18046  ? 163 GLY   A N   1 
ATOM   1282 C  CA  . GLY   A 1 166 ? -7.43755  19.82322 -52.72912 1.000 47.54037  ? 163 GLY   A CA  1 
ATOM   1283 C  C   . GLY   A 1 166 ? -6.16456  20.60884 -52.50349 1.000 51.06352  ? 163 GLY   A C   1 
ATOM   1284 O  O   . GLY   A 1 166 ? -5.05063  20.11285 -52.70758 1.000 48.09540  ? 163 GLY   A O   1 
ATOM   1285 N  N   . ASP   A 1 167 ? -6.35390  21.85629 -52.07520 1.000 51.54881  ? 164 ASP   A N   1 
ATOM   1286 C  CA  . ASP   A 1 167 ? -5.27348  22.76773 -51.71999 1.000 53.48575  ? 164 ASP   A CA  1 
ATOM   1287 C  C   . ASP   A 1 167 ? -5.20587  22.88799 -50.20075 1.000 52.06737  ? 164 ASP   A C   1 
ATOM   1288 O  O   . ASP   A 1 167 ? -6.23094  23.09599 -49.54122 1.000 50.72467  ? 164 ASP   A O   1 
ATOM   1289 C  CB  . ASP   A 1 167 ? -5.49291  24.14040 -52.37415 1.000 55.90098  ? 164 ASP   A CB  1 
ATOM   1290 C  CG  . ASP   A 1 167 ? -4.33780  25.11463 -52.13697 1.000 60.97800  ? 164 ASP   A CG  1 
ATOM   1291 O  OD1 . ASP   A 1 167 ? -3.78940  25.15212 -51.01719 1.000 72.39210  ? 164 ASP   A OD1 1 
ATOM   1292 O  OD2 . ASP   A 1 167 ? -3.97125  25.85154 -53.07917 1.000 63.53473  ? 164 ASP   A OD2 1 
ATOM   1293 N  N   . VAL   A 1 168 ? -3.99788  22.75839 -49.64902 1.000 56.55250  ? 165 VAL   A N   1 
ATOM   1294 C  CA  . VAL   A 1 168 ? -3.83654  22.83784 -48.20033 1.000 52.23923  ? 165 VAL   A CA  1 
ATOM   1295 C  C   . VAL   A 1 168 ? -4.12080  24.24759 -47.69605 1.000 55.07917  ? 165 VAL   A C   1 
ATOM   1296 O  O   . VAL   A 1 168 ? -4.74994  24.42629 -46.64665 1.000 49.37966  ? 165 VAL   A O   1 
ATOM   1297 C  CB  . VAL   A 1 168 ? -2.43186  22.36225 -47.79517 1.000 52.49298  ? 165 VAL   A CB  1 
ATOM   1298 C  CG1 . VAL   A 1 168 ? -2.13508  22.75648 -46.35933 1.000 52.62967  ? 165 VAL   A CG1 1 
ATOM   1299 C  CG2 . VAL   A 1 168 ? -2.31946  20.85998 -47.97225 1.000 44.91580  ? 165 VAL   A CG2 1 
ATOM   1300 N  N   . ARG   A 1 169 ? -3.67557  25.27161 -48.43239 1.000 54.25783  ? 166 ARG   A N   1 
ATOM   1301 C  CA  . ARG   A 1 169 ? -3.88045  26.64328 -47.97054 1.000 53.11674  ? 166 ARG   A CA  1 
ATOM   1302 C  C   . ARG   A 1 169 ? -5.35953  27.01299 -47.96264 1.000 55.15538  ? 166 ARG   A C   1 
ATOM   1303 O  O   . ARG   A 1 169 ? -5.83294  27.67815 -47.03366 1.000 55.53838  ? 166 ARG   A O   1 
ATOM   1304 C  CB  . ARG   A 1 169 ? -3.08311  27.62581 -48.82817 1.000 53.66668  ? 166 ARG   A CB  1 
ATOM   1305 C  CG  . ARG   A 1 169 ? -3.23699  29.08219 -48.39290 1.000 54.50585  ? 166 ARG   A CG  1 
ATOM   1306 C  CD  . ARG   A 1 169 ? -2.60001  30.05851 -49.37596 1.000 56.72059  ? 166 ARG   A CD  1 
ATOM   1307 N  NE  . ARG   A 1 169 ? -3.08448  29.89490 -50.73993 1.000 67.24427  ? 166 ARG   A NE  1 
ATOM   1308 C  CZ  . ARG   A 1 169 ? -4.13068  30.53920 -51.23728 1.000 62.99516  ? 166 ARG   A CZ  1 
ATOM   1309 N  NH1 . ARG   A 1 169 ? -4.81061  31.41282 -50.51274 1.000 66.49900  ? 166 ARG   A NH1 1 
ATOM   1310 N  NH2 . ARG   A 1 169 ? -4.50252  30.30280 -52.49202 1.000 74.49580  ? 166 ARG   A NH2 1 
ATOM   1311 N  N   . GLU   A 1 170 ? -6.10515  26.59699 -48.99053 1.000 59.61833  ? 167 GLU   A N   1 
ATOM   1312 C  CA  . GLU   A 1 170 ? -7.54232  26.85484 -49.00726 1.000 54.14446  ? 167 GLU   A CA  1 
ATOM   1313 C  C   . GLU   A 1 170 ? -8.24896  26.08479 -47.90041 1.000 55.74087  ? 167 GLU   A C   1 
ATOM   1314 O  O   . GLU   A 1 170 ? -9.20946  26.58426 -47.30205 1.000 56.55860  ? 167 GLU   A O   1 
ATOM   1315 C  CB  . GLU   A 1 170 ? -8.12524  26.49377 -50.37102 1.000 57.75351  ? 167 GLU   A CB  1 
ATOM   1316 C  CG  . GLU   A 1 170 ? -7.47979  27.22887 -51.52920 1.000 70.37628  ? 167 GLU   A CG  1 
ATOM   1317 C  CD  . GLU   A 1 170 ? -8.06581  26.82482 -52.86229 1.000 81.06775  ? 167 GLU   A CD  1 
ATOM   1318 O  OE1 . GLU   A 1 170 ? -8.97558  25.96701 -52.87154 1.000 83.05043  ? 167 GLU   A OE1 1 
ATOM   1319 O  OE2 . GLU   A 1 170 ? -7.61788  27.36335 -53.89736 1.000 76.62788  ? 167 GLU   A OE2 1 
ATOM   1320 N  N   . THR   A 1 171 ? -7.78771  24.86580 -47.61765 1.000 51.46440  ? 168 THR   A N   1 
ATOM   1321 C  CA  . THR   A 1 171 ? -8.37502  24.08109 -46.53764 1.000 51.66758  ? 168 THR   A CA  1 
ATOM   1322 C  C   . THR   A 1 171 ? -8.11885  24.72984 -45.18212 1.000 52.17030  ? 168 THR   A C   1 
ATOM   1323 O  O   . THR   A 1 171 ? -9.04026  24.87489 -44.37009 1.000 55.23931  ? 168 THR   A O   1 
ATOM   1324 C  CB  . THR   A 1 171 ? -7.81519  22.66256 -46.56258 1.000 48.51108  ? 168 THR   A CB  1 
ATOM   1325 O  OG1 . THR   A 1 171 ? -8.00375  22.10242 -47.86745 1.000 55.56227  ? 168 THR   A OG1 1 
ATOM   1326 C  CG2 . THR   A 1 171 ? -8.52581  21.79870 -45.53451 1.000 35.94247  ? 168 THR   A CG2 1 
ATOM   1327 N  N   . MET   A 1 172 ? -6.86885  25.11915 -44.91533 1.000 51.89355  ? 169 MET   A N   1 
ATOM   1328 C  CA  . MET   A 1 172 ? -6.56415  25.80717 -43.66275 1.000 55.08335  ? 169 MET   A CA  1 
ATOM   1329 C  C   . MET   A 1 172 ? -7.38038  27.08433 -43.52827 1.000 56.23188  ? 169 MET   A C   1 
ATOM   1330 O  O   . MET   A 1 172 ? -7.82941  27.43058 -42.42932 1.000 59.75618  ? 169 MET   A O   1 
ATOM   1331 C  CB  . MET   A 1 172 ? -5.07353  26.12975 -43.57105 1.000 52.21059  ? 169 MET   A CB  1 
ATOM   1332 C  CG  . MET   A 1 172 ? -4.16596  24.91889 -43.61993 1.000 49.41726  ? 169 MET   A CG  1 
ATOM   1333 S  SD  . MET   A 1 172 ? -4.41247  23.78223 -42.25666 1.000 61.41614  ? 169 MET   A SD  1 
ATOM   1334 C  CE  . MET   A 1 172 ? -4.02568  24.84151 -40.86891 1.000 66.19781  ? 169 MET   A CE  1 
ATOM   1335 N  N   . SER   A 1 173 ? -7.56716  27.80626 -44.63529 1.000 54.96250  ? 170 SER   A N   1 
ATOM   1336 C  CA  . SER   A 1 173 ? -8.30206  29.06549 -44.58811 1.000 54.68220  ? 170 SER   A CA  1 
ATOM   1337 C  C   . SER   A 1 173 ? -9.73724  28.84817 -44.12476 1.000 63.48997  ? 170 SER   A C   1 
ATOM   1338 O  O   . SER   A 1 173 ? -10.24405 29.58500 -43.27105 1.000 61.57652  ? 170 SER   A O   1 
ATOM   1339 C  CB  . SER   A 1 173 ? -8.27558  29.73680 -45.95963 1.000 50.99146  ? 170 SER   A CB  1 
ATOM   1340 O  OG  . SER   A 1 173 ? -9.06044  30.91732 -45.95984 1.000 62.70196  ? 170 SER   A OG  1 
ATOM   1341 N  N   . TYR   A 1 174 ? -10.40490 27.82804 -44.66928 1.000 64.25163  ? 171 TYR   A N   1 
ATOM   1342 C  CA  . TYR   A 1 174 ? -11.77100 27.53032 -44.25063 1.000 57.95388  ? 171 TYR   A CA  1 
ATOM   1343 C  C   . TYR   A 1 174 ? -11.82840 27.17979 -42.76946 1.000 57.87785  ? 171 TYR   A C   1 
ATOM   1344 O  O   . TYR   A 1 174 ? -12.73069 27.62715 -42.05207 1.000 57.79521  ? 171 TYR   A O   1 
ATOM   1345 C  CB  . TYR   A 1 174 ? -12.34251 26.38929 -45.09070 1.000 57.58560  ? 171 TYR   A CB  1 
ATOM   1346 C  CG  . TYR   A 1 174 ? -13.06681 26.85453 -46.33233 1.000 65.66451  ? 171 TYR   A CG  1 
ATOM   1347 C  CD1 . TYR   A 1 174 ? -14.23108 27.60718 -46.24347 1.000 65.46899  ? 171 TYR   A CD1 1 
ATOM   1348 C  CD2 . TYR   A 1 174 ? -12.59113 26.52979 -47.59765 1.000 70.81926  ? 171 TYR   A CD2 1 
ATOM   1349 C  CE1 . TYR   A 1 174 ? -14.89671 28.03464 -47.38362 1.000 78.13831  ? 171 TYR   A CE1 1 
ATOM   1350 C  CE2 . TYR   A 1 174 ? -13.24987 26.94917 -48.74244 1.000 71.79414  ? 171 TYR   A CE2 1 
ATOM   1351 C  CZ  . TYR   A 1 174 ? -14.40092 27.70106 -48.63105 1.000 76.96336  ? 171 TYR   A CZ  1 
ATOM   1352 O  OH  . TYR   A 1 174 ? -15.05457 28.11846 -49.77020 1.000 80.53238  ? 171 TYR   A OH  1 
ATOM   1353 N  N   . LEU   A 1 175 ? -10.88180 26.36448 -42.29808 1.000 56.48206  ? 172 LEU   A N   1 
ATOM   1354 C  CA  . LEU   A 1 175 ? -10.88673 25.95423 -40.89823 1.000 55.44520  ? 172 LEU   A CA  1 
ATOM   1355 C  C   . LEU   A 1 175 ? -10.64857 27.13737 -39.96969 1.000 61.09528  ? 172 LEU   A C   1 
ATOM   1356 O  O   . LEU   A 1 175 ? -11.24121 27.20899 -38.88690 1.000 66.58349  ? 172 LEU   A O   1 
ATOM   1357 C  CB  . LEU   A 1 175 ? -9.83878  24.86898 -40.66776 1.000 52.06061  ? 172 LEU   A CB  1 
ATOM   1358 C  CG  . LEU   A 1 175 ? -10.09670 23.57296 -41.43607 1.000 58.84166  ? 172 LEU   A CG  1 
ATOM   1359 C  CD1 . LEU   A 1 175 ? -8.99191  22.56912 -41.18656 1.000 57.80498  ? 172 LEU   A CD1 1 
ATOM   1360 C  CD2 . LEU   A 1 175 ? -11.44136 22.98712 -41.04383 1.000 59.49443  ? 172 LEU   A CD2 1 
ATOM   1361 N  N   . PHE   A 1 176 ? -9.78620  28.07562 -40.37029 1.000 60.97700  ? 173 PHE   A N   1 
ATOM   1362 C  CA  . PHE   A 1 176 ? -9.56401  29.25729 -39.54231 1.000 58.11416  ? 173 PHE   A CA  1 
ATOM   1363 C  C   . PHE   A 1 176 ? -10.82958 30.09373 -39.42183 1.000 61.26248  ? 173 PHE   A C   1 
ATOM   1364 O  O   . PHE   A 1 176 ? -11.06930 30.70673 -38.37521 1.000 63.29733  ? 173 PHE   A O   1 
ATOM   1365 C  CB  . PHE   A 1 176 ? -8.42030  30.10299 -40.10555 1.000 58.58997  ? 173 PHE   A CB  1 
ATOM   1366 C  CG  . PHE   A 1 176 ? -7.08385  29.40962 -40.10022 1.000 52.51009  ? 173 PHE   A CG  1 
ATOM   1367 C  CD1 . PHE   A 1 176 ? -6.84857  28.32258 -39.27325 1.000 55.82730  ? 173 PHE   A CD1 1 
ATOM   1368 C  CD2 . PHE   A 1 176 ? -6.05658  29.85839 -40.91418 1.000 43.04176  ? 173 PHE   A CD2 1 
ATOM   1369 C  CE1 . PHE   A 1 176 ? -5.61783  27.68856 -39.26747 1.000 45.68051  ? 173 PHE   A CE1 1 
ATOM   1370 C  CE2 . PHE   A 1 176 ? -4.82321  29.23045 -40.91081 1.000 45.77874  ? 173 PHE   A CE2 1 
ATOM   1371 C  CZ  . PHE   A 1 176 ? -4.60408  28.14626 -40.08576 1.000 45.97709  ? 173 PHE   A CZ  1 
ATOM   1372 N  N   . GLN   A 1 177 ? -11.65209 30.12785 -40.47484 1.000 58.12006  ? 174 GLN   A N   1 
ATOM   1373 C  CA  A GLN   A 1 177 ? -12.92123 30.84403 -40.40939 0.497 59.14731  ? 174 GLN   A CA  1 
ATOM   1374 C  CA  B GLN   A 1 177 ? -12.91568 30.85056 -40.40100 0.503 59.27376  ? 174 GLN   A CA  1 
ATOM   1375 C  C   . GLN   A 1 177 ? -13.85286 30.26364 -39.35272 1.000 61.07267  ? 174 GLN   A C   1 
ATOM   1376 O  O   . GLN   A 1 177 ? -14.77817 30.95288 -38.90966 1.000 65.42697  ? 174 GLN   A O   1 
ATOM   1377 C  CB  A GLN   A 1 177 ? -13.61264 30.82304 -41.77516 0.497 57.95012  ? 174 GLN   A CB  1 
ATOM   1378 C  CB  B GLN   A 1 177 ? -13.59678 30.85918 -41.77040 0.503 57.03280  ? 174 GLN   A CB  1 
ATOM   1379 C  CG  A GLN   A 1 177 ? -12.80147 31.43252 -42.91074 0.497 61.58416  ? 174 GLN   A CG  1 
ATOM   1380 C  CG  B GLN   A 1 177 ? -12.78989 31.55428 -42.85522 0.503 61.57247  ? 174 GLN   A CG  1 
ATOM   1381 C  CD  A GLN   A 1 177 ? -13.18811 32.86806 -43.21183 0.497 62.19827  ? 174 GLN   A CD  1 
ATOM   1382 C  CD  B GLN   A 1 177 ? -13.39240 31.38064 -44.23567 0.503 61.99499  ? 174 GLN   A CD  1 
ATOM   1383 O  OE1 A GLN   A 1 177 ? -13.94442 33.48968 -42.46584 0.497 65.22598  ? 174 GLN   A OE1 1 
ATOM   1384 O  OE1 B GLN   A 1 177 ? -14.55687 31.00556 -44.37521 0.503 63.35321  ? 174 GLN   A OE1 1 
ATOM   1385 N  NE2 A GLN   A 1 177 ? -12.67301 33.40041 -44.31560 0.497 58.52321  ? 174 GLN   A NE2 1 
ATOM   1386 N  NE2 B GLN   A 1 177 ? -12.59728 31.64782 -45.26600 0.503 59.84539  ? 174 GLN   A NE2 1 
ATOM   1387 N  N   . HIS   A 1 178 ? -13.63499 29.01270 -38.94373 1.000 54.02417  ? 175 HIS   A N   1 
ATOM   1388 C  CA  . HIS   A 1 178 ? -14.44149 28.36689 -37.91606 1.000 59.34763  ? 175 HIS   A CA  1 
ATOM   1389 C  C   . HIS   A 1 178 ? -13.68046 28.22114 -36.60264 1.000 61.75426  ? 175 HIS   A C   1 
ATOM   1390 O  O   . HIS   A 1 178 ? -14.09280 27.45191 -35.72806 1.000 59.47541  ? 175 HIS   A O   1 
ATOM   1391 C  CB  . HIS   A 1 178 ? -14.93650 27.00289 -38.40101 1.000 53.92714  ? 175 HIS   A CB  1 
ATOM   1392 C  CG  . HIS   A 1 178 ? -15.84011 27.07793 -39.59318 1.000 61.37356  ? 175 HIS   A CG  1 
ATOM   1393 N  ND1 . HIS   A 1 178 ? -15.37206 27.00641 -40.88726 1.000 60.08280  ? 175 HIS   A ND1 1 
ATOM   1394 C  CD2 . HIS   A 1 178 ? -17.18320 27.22491 -39.68765 1.000 64.43556  ? 175 HIS   A CD2 1 
ATOM   1395 C  CE1 . HIS   A 1 178 ? -16.38715 27.10247 -41.72744 1.000 59.74121  ? 175 HIS   A CE1 1 
ATOM   1396 N  NE2 . HIS   A 1 178 ? -17.49763 27.23632 -41.02528 1.000 69.74869  ? 175 HIS   A NE2 1 
ATOM   1397 N  N   . ALA   A 1 179 ? -12.57823 28.94671 -36.44715 1.000 60.39791  ? 176 ALA   A N   1 
ATOM   1398 C  CA  . ALA   A 1 179 ? -11.76999 28.90036 -35.24176 1.000 57.55933  ? 176 ALA   A CA  1 
ATOM   1399 C  C   . ALA   A 1 179 ? -11.80110 30.25737 -34.55521 1.000 59.43053  ? 176 ALA   A C   1 
ATOM   1400 O  O   . ALA   A 1 179 ? -12.10196 31.28497 -35.16862 1.000 60.20793  ? 176 ALA   A O   1 
ATOM   1401 C  CB  . ALA   A 1 179 ? -10.32230 28.50050 -35.55219 1.000 58.81451  ? 176 ALA   A CB  1 
ATOM   1402 N  N   . ASN   A 1 180 ? -11.48492 30.24633 -33.26512 1.000 71.30230  ? 177 ASN   A N   1 
ATOM   1403 C  CA  . ASN   A 1 180 ? -11.50216 31.45693 -32.44885 1.000 69.39244  ? 177 ASN   A CA  1 
ATOM   1404 C  C   . ASN   A 1 180 ? -10.18771 32.19327 -32.66466 1.000 63.13334  ? 177 ASN   A C   1 
ATOM   1405 O  O   . ASN   A 1 180 ? -9.21555  32.00290 -31.93587 1.000 69.68515  ? 177 ASN   A O   1 
ATOM   1406 C  CB  . ASN   A 1 180 ? -11.71529 31.10770 -30.98191 1.000 71.16035  ? 177 ASN   A CB  1 
ATOM   1407 C  CG  . ASN   A 1 180 ? -12.00473 32.32370 -30.12965 1.000 83.57154  ? 177 ASN   A CG  1 
ATOM   1408 O  OD1 . ASN   A 1 180 ? -11.79673 33.46148 -30.55243 1.000 88.07958  ? 177 ASN   A OD1 1 
ATOM   1409 N  ND2 . ASN   A 1 180 ? -12.50168 32.08854 -28.92046 1.000 79.55885  ? 177 ASN   A ND2 1 
ATOM   1410 N  N   . LEU   A 1 181 ? -10.15709 33.04198 -33.69038 1.000 65.42869  ? 178 LEU   A N   1 
ATOM   1411 C  CA  . LEU   A 1 181 ? -9.00877  33.89206 -33.97553 1.000 71.62322  ? 178 LEU   A CA  1 
ATOM   1412 C  C   . LEU   A 1 181 ? -9.35069  35.36534 -33.78501 1.000 79.13289  ? 178 LEU   A C   1 
ATOM   1413 O  O   . LEU   A 1 181 ? -8.78061  36.23675 -34.44647 1.000 78.18694  ? 178 LEU   A O   1 
ATOM   1414 C  CB  . LEU   A 1 181 ? -8.49327  33.64639 -35.39288 1.000 67.41109  ? 178 LEU   A CB  1 
ATOM   1415 C  CG  . LEU   A 1 181 ? -8.04588  32.22549 -35.73815 1.000 59.72160  ? 178 LEU   A CG  1 
ATOM   1416 C  CD1 . LEU   A 1 181 ? -7.53901  32.16772 -37.16445 1.000 63.65113  ? 178 LEU   A CD1 1 
ATOM   1417 C  CD2 . LEU   A 1 181 ? -6.97646  31.74560 -34.77618 1.000 62.68816  ? 178 LEU   A CD2 1 
ATOM   1418 N  N   . ASP   A 1 182 ? -10.28520 35.65094 -32.87720 1.000 84.32873  ? 179 ASP   A N   1 
ATOM   1419 C  CA  . ASP   A 1 182 ? -10.70337 37.02785 -32.64785 1.000 90.74325  ? 179 ASP   A CA  1 
ATOM   1420 C  C   . ASP   A 1 182 ? -9.61969  37.82846 -31.93845 1.000 94.74473  ? 179 ASP   A C   1 
ATOM   1421 O  O   . ASP   A 1 182 ? -9.51497  39.04372 -32.14106 1.000 96.00425  ? 179 ASP   A O   1 
ATOM   1422 C  CB  . ASP   A 1 182 ? -12.01059 37.04605 -31.85685 1.000 96.28273  ? 179 ASP   A CB  1 
ATOM   1423 C  CG  . ASP   A 1 182 ? -13.16881 36.44782 -32.63794 1.000 100.52354 ? 179 ASP   A CG  1 
ATOM   1424 O  OD1 . ASP   A 1 182 ? -13.12703 36.48056 -33.88770 1.000 94.37153  ? 179 ASP   A OD1 1 
ATOM   1425 O  OD2 . ASP   A 1 182 ? -14.11584 35.93650 -32.00404 1.000 104.14670 ? 179 ASP   A OD2 1 
ATOM   1426 N  N   . SER   A 1 183 ? -8.80683  37.17109 -31.10917 1.000 85.69681  ? 180 SER   A N   1 
ATOM   1427 C  CA  . SER   A 1 183 ? -7.73120  37.86306 -30.41321 1.000 81.90773  ? 180 SER   A CA  1 
ATOM   1428 C  C   . SER   A 1 183 ? -6.58096  38.23312 -31.33900 1.000 85.96170  ? 180 SER   A C   1 
ATOM   1429 O  O   . SER   A 1 183 ? -5.74003  39.05285 -30.95507 1.000 91.52901  ? 180 SER   A O   1 
ATOM   1430 C  CB  . SER   A 1 183 ? -7.20114  36.99460 -29.26848 1.000 88.19411  ? 180 SER   A CB  1 
ATOM   1431 O  OG  . SER   A 1 183 ? -8.23808  36.62012 -28.37751 1.000 101.40351 ? 180 SER   A OG  1 
ATOM   1432 N  N   . CYS   A 1 184 ? -6.52986  37.66264 -32.54087 1.000 83.84430  ? 181 CYS   A N   1 
ATOM   1433 C  CA  . CYS   A 1 184 ? -5.40180  37.86618 -33.43899 1.000 76.94462  ? 181 CYS   A CA  1 
ATOM   1434 C  C   . CYS   A 1 184 ? -5.48971  39.22177 -34.12554 1.000 81.27416  ? 181 CYS   A C   1 
ATOM   1435 O  O   . CYS   A 1 184 ? -6.49704  39.54357 -34.76338 1.000 87.56001  ? 181 CYS   A O   1 
ATOM   1436 C  CB  . CYS   A 1 184 ? -5.34200  36.75025 -34.47863 1.000 78.07803  ? 181 CYS   A CB  1 
ATOM   1437 S  SG  . CYS   A 1 184 ? -5.13118  35.11923 -33.74926 1.000 76.97974  ? 181 CYS   A SG  1 
ATOM   1438 N  N   . LYS   A 1 185 ? -4.42459  40.00874 -33.99860 1.000 68.83825  ? 182 LYS   A N   1 
ATOM   1439 C  CA  . LYS   A 1 185 ? -4.32162  41.32042 -34.62008 1.000 80.48261  ? 182 LYS   A CA  1 
ATOM   1440 C  C   . LYS   A 1 185 ? -3.02345  41.40063 -35.40765 1.000 72.61183  ? 182 LYS   A C   1 
ATOM   1441 O  O   . LYS   A 1 185 ? -2.00522  40.83803 -34.99600 1.000 77.47724  ? 182 LYS   A O   1 
ATOM   1442 C  CB  . LYS   A 1 185 ? -4.36353  42.44609 -33.57030 1.000 81.59492  ? 182 LYS   A CB  1 
ATOM   1443 C  CG  . LYS   A 1 185 ? -4.21860  43.84533 -34.16017 1.000 89.93938  ? 182 LYS   A CG  1 
ATOM   1444 C  CD  . LYS   A 1 185 ? -3.52257  44.81045 -33.20940 1.000 98.59054  ? 182 LYS   A CD  1 
ATOM   1445 C  CE  . LYS   A 1 185 ? -4.49075  45.41599 -32.20963 1.000 97.01925  ? 182 LYS   A CE  1 
ATOM   1446 N  NZ  . LYS   A 1 185 ? -3.86635  46.55415 -31.48097 1.000 99.89592  ? 182 LYS   A NZ  1 
ATOM   1447 N  N   . ARG   A 1 186 ? -3.05951  42.10332 -36.53776 1.000 68.31406  ? 183 ARG   A N   1 
ATOM   1448 C  CA  . ARG   A 1 186 ? -1.86121  42.34426 -37.33360 1.000 73.31164  ? 183 ARG   A CA  1 
ATOM   1449 C  C   . ARG   A 1 186 ? -1.93436  43.74282 -37.92292 1.000 79.28252  ? 183 ARG   A C   1 
ATOM   1450 O  O   . ARG   A 1 186 ? -2.87217  44.06237 -38.65819 1.000 84.60265  ? 183 ARG   A O   1 
ATOM   1451 C  CB  . ARG   A 1 186 ? -1.69321  41.30148 -38.44036 1.000 73.65674  ? 183 ARG   A CB  1 
ATOM   1452 C  CG  . ARG   A 1 186 ? -0.63058  41.67852 -39.45933 1.000 73.11874  ? 183 ARG   A CG  1 
ATOM   1453 C  CD  . ARG   A 1 186 ? -0.62465  40.72997 -40.64110 1.000 67.47593  ? 183 ARG   A CD  1 
ATOM   1454 N  NE  . ARG   A 1 186 ? -0.06942  39.43671 -40.26149 1.000 66.82351  ? 183 ARG   A NE  1 
ATOM   1455 C  CZ  . ARG   A 1 186 ? 0.10111   38.41465 -41.08860 1.000 71.88421  ? 183 ARG   A CZ  1 
ATOM   1456 N  NH1 . ARG   A 1 186 ? -0.23354  38.49453 -42.36662 1.000 71.83558  ? 183 ARG   A NH1 1 
ATOM   1457 N  NH2 . ARG   A 1 186 ? 0.62295   37.28409 -40.62154 1.000 67.60805  ? 183 ARG   A NH2 1 
ATOM   1458 N  N   . VAL   A 1 187 ? -0.94463  44.56663 -37.59298 1.000 83.22840  ? 184 VAL   A N   1 
ATOM   1459 C  CA  . VAL   A 1 187 ? -0.82248  45.92478 -38.10697 1.000 82.19299  ? 184 VAL   A CA  1 
ATOM   1460 C  C   . VAL   A 1 187 ? 0.26174   45.94386 -39.17601 1.000 85.54877  ? 184 VAL   A C   1 
ATOM   1461 O  O   . VAL   A 1 187 ? 1.39314   45.50628 -38.93097 1.000 85.66918  ? 184 VAL   A O   1 
ATOM   1462 C  CB  . VAL   A 1 187 ? -0.50277  46.92210 -36.98063 1.000 83.15255  ? 184 VAL   A CB  1 
ATOM   1463 C  CG1 . VAL   A 1 187 ? -0.47272  48.33970 -37.52344 1.000 84.79648  ? 184 VAL   A CG1 1 
ATOM   1464 C  CG2 . VAL   A 1 187 ? -1.51861  46.79619 -35.85367 1.000 77.63446  ? 184 VAL   A CG2 1 
ATOM   1465 N  N   . LEU   A 1 188 ? -0.08381  46.42847 -40.36638 1.000 86.17901  ? 185 LEU   A N   1 
ATOM   1466 C  CA  . LEU   A 1 188 ? 0.83973   46.47782 -41.48750 1.000 86.95582  ? 185 LEU   A CA  1 
ATOM   1467 C  C   . LEU   A 1 188 ? 1.06480   47.92248 -41.90994 1.000 94.97777  ? 185 LEU   A C   1 
ATOM   1468 O  O   . LEU   A 1 188 ? 0.23301   48.80334 -41.67478 1.000 94.82760  ? 185 LEU   A O   1 
ATOM   1469 C  CB  . LEU   A 1 188 ? 0.31467   45.67065 -42.68366 1.000 86.70397  ? 185 LEU   A CB  1 
ATOM   1470 C  CG  . LEU   A 1 188 ? 0.13560   44.17181 -42.44642 1.000 91.17246  ? 185 LEU   A CG  1 
ATOM   1471 C  CD1 . LEU   A 1 188 ? -0.49792  43.49995 -43.65365 1.000 90.63297  ? 185 LEU   A CD1 1 
ATOM   1472 C  CD2 . LEU   A 1 188 ? 1.46922   43.52811 -42.11483 1.000 90.42992  ? 185 LEU   A CD2 1 
ATOM   1473 N  N   . ASN   A 1 189 ? 2.21373   48.15937 -42.53510 1.000 96.36620  ? 186 ASN   A N   1 
ATOM   1474 C  CA  . ASN   A 1 189 ? 2.56631   49.48447 -43.02067 1.000 100.63420 ? 186 ASN   A CA  1 
ATOM   1475 C  C   . ASN   A 1 189 ? 3.13127   49.34876 -44.42329 1.000 102.13520 ? 186 ASN   A C   1 
ATOM   1476 O  O   . ASN   A 1 189 ? 3.98555   48.49273 -44.67016 1.000 100.36407 ? 186 ASN   A O   1 
ATOM   1477 C  CB  . ASN   A 1 189 ? 3.58520   50.16352 -42.09745 1.000 101.83086 ? 186 ASN   A CB  1 
ATOM   1478 C  CG  . ASN   A 1 189 ? 3.55739   51.67542 -42.20551 1.000 105.76464 ? 186 ASN   A CG  1 
ATOM   1479 O  OD1 . ASN   A 1 189 ? 2.71202   52.33631 -41.60139 1.000 103.16770 ? 186 ASN   A OD1 1 
ATOM   1480 N  ND2 . ASN   A 1 189 ? 4.49471   52.23227 -42.96470 1.000 107.66505 ? 186 ASN   A ND2 1 
ATOM   1481 N  N   . VAL   A 1 190 ? 2.64584   50.18495 -45.33558 1.000 103.36221 ? 187 VAL   A N   1 
ATOM   1482 C  CA  . VAL   A 1 190 ? 3.12043   50.22035 -46.71489 1.000 108.27022 ? 187 VAL   A CA  1 
ATOM   1483 C  C   . VAL   A 1 190 ? 3.70324   51.60306 -46.97718 1.000 115.96549 ? 187 VAL   A C   1 
ATOM   1484 O  O   . VAL   A 1 190 ? 2.99270   52.61064 -46.87707 1.000 113.42456 ? 187 VAL   A O   1 
ATOM   1485 C  CB  . VAL   A 1 190 ? 1.99851   49.90151 -47.71365 1.000 105.44641 ? 187 VAL   A CB  1 
ATOM   1486 C  CG1 . VAL   A 1 190 ? 2.56406   49.76883 -49.12074 1.000 98.34378  ? 187 VAL   A CG1 1 
ATOM   1487 C  CG2 . VAL   A 1 190 ? 1.26976   48.64013 -47.29973 1.000 101.23733 ? 187 VAL   A CG2 1 
ATOM   1488 N  N   . VAL   A 1 191 ? 4.99152   51.64965 -47.31274 1.000 118.67928 ? 188 VAL   A N   1 
ATOM   1489 C  CA  . VAL   A 1 191 ? 5.67678   52.90161 -47.61950 1.000 123.61939 ? 188 VAL   A CA  1 
ATOM   1490 C  C   . VAL   A 1 191 ? 5.84535   53.00954 -49.13028 1.000 124.18768 ? 188 VAL   A C   1 
ATOM   1491 O  O   . VAL   A 1 191 ? 6.32634   52.07531 -49.78827 1.000 118.44307 ? 188 VAL   A O   1 
ATOM   1492 C  CB  . VAL   A 1 191 ? 7.02786   52.99701 -46.88246 1.000 122.24986 ? 188 VAL   A CB  1 
ATOM   1493 C  CG1 . VAL   A 1 191 ? 7.98821   51.88120 -47.29332 1.000 118.73619 ? 188 VAL   A CG1 1 
ATOM   1494 C  CG2 . VAL   A 1 191 ? 7.64851   54.37581 -47.07915 1.000 122.52648 ? 188 VAL   A CG2 1 
ATOM   1495 N  N   . CYS   A 1 192 ? 5.41332   54.13864 -49.68956 1.000 131.35139 ? 189 CYS   A N   1 
ATOM   1496 C  CA  . CYS   A 1 192 ? 5.47046   54.38322 -51.12767 1.000 135.63404 ? 189 CYS   A CA  1 
ATOM   1497 C  C   . CYS   A 1 192 ? 6.15743   55.72306 -51.34653 1.000 141.08596 ? 189 CYS   A C   1 
ATOM   1498 O  O   . CYS   A 1 192 ? 5.64527   56.76114 -50.91983 1.000 138.19951 ? 189 CYS   A O   1 
ATOM   1499 C  CB  . CYS   A 1 192 ? 4.07443   54.37936 -51.75461 1.000 140.23925 ? 189 CYS   A CB  1 
ATOM   1500 S  SG  . CYS   A 1 192 ? 4.01473   55.03849 -53.44640 1.000 156.13274 ? 189 CYS   A SG  1 
ATOM   1501 N  N   . LYS   A 1 193 ? 7.32021   55.67724 -52.00396 1.000 146.27914 ? 190 LYS   A N   1 
ATOM   1502 C  CA  . LYS   A 1 193 ? 8.12832   56.86338 -52.25320 1.000 147.66404 ? 190 LYS   A CA  1 
ATOM   1503 C  C   . LYS   A 1 193 ? 7.28596   58.04081 -52.71875 1.000 148.73538 ? 190 LYS   A C   1 
ATOM   1504 O  O   . LYS   A 1 193 ? 7.37145   59.14429 -52.16843 1.000 144.44196 ? 190 LYS   A O   1 
ATOM   1505 C  CB  . LYS   A 1 193 ? 9.20864   56.53625 -53.28758 1.000 138.00372 ? 190 LYS   A CB  1 
ATOM   1506 C  CG  . LYS   A 1 193 ? 10.11247  57.70694 -53.62477 1.000 143.21248 ? 190 LYS   A CG  1 
ATOM   1507 C  CD  . LYS   A 1 193 ? 11.13950  57.32968 -54.68375 1.000 140.91633 ? 190 LYS   A CD  1 
ATOM   1508 C  CE  . LYS   A 1 193 ? 12.06312  58.49686 -55.01078 1.000 138.84942 ? 190 LYS   A CE  1 
ATOM   1509 N  NZ  . LYS   A 1 193 ? 13.07922  58.13674 -56.04142 1.000 142.58081 ? 190 LYS   A NZ  1 
ATOM   1510 N  N   . THR   A 1 194 ? 6.43592   57.81643 -53.72765 1.000 143.67131 ? 191 THR   A N   1 
ATOM   1511 C  CA  . THR   A 1 194 ? 5.58349   58.88368 -54.24016 1.000 142.29510 ? 191 THR   A CA  1 
ATOM   1512 C  C   . THR   A 1 194 ? 4.37547   59.12236 -53.33563 1.000 143.40278 ? 191 THR   A C   1 
ATOM   1513 O  O   . THR   A 1 194 ? 4.27120   60.16755 -52.68364 1.000 141.64197 ? 191 THR   A O   1 
ATOM   1514 C  CB  . THR   A 1 194 ? 5.13917   58.55903 -55.66881 1.000 139.96363 ? 191 THR   A CB  1 
ATOM   1515 N  N   . CYS   A 1 195 ? 3.45008   58.15828 -53.28354 1.000 144.81975 ? 192 CYS   A N   1 
ATOM   1516 C  CA  . CYS   A 1 195 ? 2.18141   58.36828 -52.58712 1.000 144.37242 ? 192 CYS   A CA  1 
ATOM   1517 C  C   . CYS   A 1 195 ? 2.39313   58.63559 -51.10257 1.000 139.43407 ? 192 CYS   A C   1 
ATOM   1518 O  O   . CYS   A 1 195 ? 1.87919   59.61791 -50.55600 1.000 139.66402 ? 192 CYS   A O   1 
ATOM   1519 C  CB  . CYS   A 1 195 ? 1.26105   57.16328 -52.78483 1.000 145.57885 ? 192 CYS   A CB  1 
ATOM   1520 N  N   . GLY   A 1 196 ? 3.13173   57.76168 -50.42509 1.000 133.82757 ? 193 GLY   A N   1 
ATOM   1521 C  CA  . GLY   A 1 196 ? 3.40620   57.98205 -49.02017 1.000 128.13870 ? 193 GLY   A CA  1 
ATOM   1522 C  C   . GLY   A 1 196 ? 3.31705   56.74587 -48.15091 1.000 121.39884 ? 193 GLY   A C   1 
ATOM   1523 O  O   . GLY   A 1 196 ? 3.64538   55.63934 -48.58559 1.000 122.72327 ? 193 GLY   A O   1 
ATOM   1524 N  N   . GLN   A 1 197 ? 2.87970   56.93089 -46.90814 1.000 121.10769 ? 194 GLN   A N   1 
ATOM   1525 C  CA  . GLN   A 1 197 ? 2.79947   55.85593 -45.93119 1.000 120.14685 ? 194 GLN   A CA  1 
ATOM   1526 C  C   . GLN   A 1 197 ? 1.35883   55.63665 -45.49445 1.000 115.84851 ? 194 GLN   A C   1 
ATOM   1527 O  O   . GLN   A 1 197 ? 0.62954   56.59011 -45.20225 1.000 112.68961 ? 194 GLN   A O   1 
ATOM   1528 C  CB  . GLN   A 1 197 ? 3.67025   56.14794 -44.70559 1.000 118.02867 ? 194 GLN   A CB  1 
ATOM   1529 C  CG  . GLN   A 1 197 ? 4.94695   55.31973 -44.64919 1.000 119.35951 ? 194 GLN   A CG  1 
ATOM   1530 C  CD  . GLN   A 1 197 ? 5.87617   55.74706 -43.52751 1.000 119.67103 ? 194 GLN   A CD  1 
ATOM   1531 O  OE1 . GLN   A 1 197 ? 5.49659   56.52598 -42.65324 1.000 117.07767 ? 194 GLN   A OE1 1 
ATOM   1532 N  NE2 . GLN   A 1 197 ? 7.10462   55.24110 -43.55160 1.000 113.76288 ? 194 GLN   A NE2 1 
ATOM   1533 N  N   . GLN   A 1 198 ? 0.96699   54.36690 -45.43277 1.000 111.96097 ? 195 GLN   A N   1 
ATOM   1534 C  CA  . GLN   A 1 198 ? -0.37534  53.96544 -45.03852 1.000 111.13866 ? 195 GLN   A CA  1 
ATOM   1535 C  C   . GLN   A 1 198 ? -0.27960  52.77203 -44.10067 1.000 110.45227 ? 195 GLN   A C   1 
ATOM   1536 O  O   . GLN   A 1 198 ? 0.37331   51.77509 -44.42521 1.000 109.30277 ? 195 GLN   A O   1 
ATOM   1537 C  CB  . GLN   A 1 198 ? -1.22321  53.61213 -46.26761 1.000 111.11149 ? 195 GLN   A CB  1 
ATOM   1538 C  CG  . GLN   A 1 198 ? -2.51564  52.88086 -45.94871 1.000 120.41830 ? 195 GLN   A CG  1 
ATOM   1539 C  CD  . GLN   A 1 198 ? -3.50304  53.73109 -45.17023 1.000 125.05321 ? 195 GLN   A CD  1 
ATOM   1540 O  OE1 . GLN   A 1 198 ? -3.68494  54.91523 -45.45706 1.000 124.23279 ? 195 GLN   A OE1 1 
ATOM   1541 N  NE2 . GLN   A 1 198 ? -4.14854  53.12689 -44.17799 1.000 124.90048 ? 195 GLN   A NE2 1 
ATOM   1542 N  N   . GLN   A 1 199 ? -0.92733  52.87273 -42.94303 1.000 108.20343 ? 196 GLN   A N   1 
ATOM   1543 C  CA  . GLN   A 1 199 ? -0.88781  51.82721 -41.92707 1.000 103.14952 ? 196 GLN   A CA  1 
ATOM   1544 C  C   . GLN   A 1 199 ? -2.27776  51.22347 -41.77071 1.000 105.85442 ? 196 GLN   A C   1 
ATOM   1545 O  O   . GLN   A 1 199 ? -3.22308  51.92041 -41.38402 1.000 107.65917 ? 196 GLN   A O   1 
ATOM   1546 C  CB  . GLN   A 1 199 ? -0.38695  52.37564 -40.59049 1.000 98.08064  ? 196 GLN   A CB  1 
ATOM   1547 C  CG  . GLN   A 1 199 ? -0.03161  51.28886 -39.58711 1.000 101.56122 ? 196 GLN   A CG  1 
ATOM   1548 C  CD  . GLN   A 1 199 ? 0.29704   51.83520 -38.21141 1.000 101.27952 ? 196 GLN   A CD  1 
ATOM   1549 O  OE1 . GLN   A 1 199 ? 1.45224   52.13931 -37.91001 1.000 99.20643  ? 196 GLN   A OE1 1 
ATOM   1550 N  NE2 . GLN   A 1 199 ? -0.72016  51.95514 -37.36448 1.000 86.64936  ? 196 GLN   A NE2 1 
ATOM   1551 N  N   . THR   A 1 200 ? -2.39549  49.93258 -42.06519 1.000 101.58387 ? 197 THR   A N   1 
ATOM   1552 C  CA  . THR   A 1 200 ? -3.64045  49.19435 -41.92202 1.000 96.48954  ? 197 THR   A CA  1 
ATOM   1553 C  C   . THR   A 1 200 ? -3.50512  48.15363 -40.81824 1.000 92.41232  ? 197 THR   A C   1 
ATOM   1554 O  O   . THR   A 1 200 ? -2.40362  47.71290 -40.47970 1.000 94.99428  ? 197 THR   A O   1 
ATOM   1555 C  CB  . THR   A 1 200 ? -4.03183  48.50402 -43.23468 1.000 99.88278  ? 197 THR   A CB  1 
ATOM   1556 O  OG1 . THR   A 1 200 ? -3.26509  47.30230 -43.39251 1.000 92.09689  ? 197 THR   A OG1 1 
ATOM   1557 C  CG2 . THR   A 1 200 ? -3.77150  49.42341 -44.42040 1.000 99.30690  ? 197 THR   A CG2 1 
ATOM   1558 N  N   . THR   A 1 201 ? -4.64430  47.76782 -40.25311 1.000 87.77417  ? 198 THR   A N   1 
ATOM   1559 C  CA  . THR   A 1 201 ? -4.70648  46.70300 -39.26350 1.000 88.44727  ? 198 THR   A CA  1 
ATOM   1560 C  C   . THR   A 1 201 ? -5.67404  45.63184 -39.74374 1.000 88.34819  ? 198 THR   A C   1 
ATOM   1561 O  O   . THR   A 1 201 ? -6.75579  45.94282 -40.25448 1.000 82.67896  ? 198 THR   A O   1 
ATOM   1562 C  CB  . THR   A 1 201 ? -5.15112  47.22040 -37.88350 1.000 89.72673  ? 198 THR   A CB  1 
ATOM   1563 O  OG1 . THR   A 1 201 ? -6.55733  47.49222 -37.90240 1.000 96.60450  ? 198 THR   A OG1 1 
ATOM   1564 C  CG2 . THR   A 1 201 ? -4.39555  48.49198 -37.50449 1.000 91.10726  ? 198 THR   A CG2 1 
ATOM   1565 N  N   . LEU   A 1 202 ? -5.27980  44.37191 -39.58584 1.000 86.61909  ? 199 LEU   A N   1 
ATOM   1566 C  CA  . LEU   A 1 202 ? -6.10039  43.23669 -39.97163 1.000 79.00200  ? 199 LEU   A CA  1 
ATOM   1567 C  C   . LEU   A 1 202 ? -6.42785  42.41960 -38.73018 1.000 73.16294  ? 199 LEU   A C   1 
ATOM   1568 O  O   . LEU   A 1 202 ? -5.60788  42.30878 -37.81213 1.000 70.96876  ? 199 LEU   A O   1 
ATOM   1569 C  CB  . LEU   A 1 202 ? -5.39683  42.36064 -41.01851 1.000 74.39223  ? 199 LEU   A CB  1 
ATOM   1570 C  CG  . LEU   A 1 202 ? -5.08589  43.01112 -42.37373 1.000 71.59406  ? 199 LEU   A CG  1 
ATOM   1571 C  CD1 . LEU   A 1 202 ? -3.84541  43.90604 -42.33364 1.000 82.06923  ? 199 LEU   A CD1 1 
ATOM   1572 C  CD2 . LEU   A 1 202 ? -4.93798  41.95574 -43.45271 1.000 78.76176  ? 199 LEU   A CD2 1 
ATOM   1573 N  N   . LYS   A 1 203 ? -7.63265  41.85383 -38.70656 1.000 76.53488  ? 200 LYS   A N   1 
ATOM   1574 C  CA  . LYS   A 1 203 ? -8.10108  41.03472 -37.60245 1.000 75.95140  ? 200 LYS   A CA  1 
ATOM   1575 C  C   . LYS   A 1 203 ? -8.55657  39.68250 -38.13051 1.000 78.51529  ? 200 LYS   A C   1 
ATOM   1576 O  O   . LYS   A 1 203 ? -8.78819  39.50527 -39.32931 1.000 79.08311  ? 200 LYS   A O   1 
ATOM   1577 C  CB  . LYS   A 1 203 ? -9.25838  41.71708 -36.85907 1.000 77.31588  ? 200 LYS   A CB  1 
ATOM   1578 C  CG  . LYS   A 1 203 ? -8.82386  42.61824 -35.71781 1.000 96.69721  ? 200 LYS   A CG  1 
ATOM   1579 C  CD  . LYS   A 1 203 ? -10.01688 43.33524 -35.10044 1.000 106.14713 ? 200 LYS   A CD  1 
ATOM   1580 C  CE  . LYS   A 1 203 ? -9.58110  44.55514 -34.30055 1.000 108.64875 ? 200 LYS   A CE  1 
ATOM   1581 N  NZ  . LYS   A 1 203 ? -8.57365  44.21619 -33.25743 1.000 111.55410 ? 200 LYS   A NZ  1 
ATOM   1582 N  N   . GLY   A 1 204 ? -8.67697  38.72231 -37.21549 1.000 77.48313  ? 201 GLY   A N   1 
ATOM   1583 C  CA  . GLY   A 1 204 ? -9.21249  37.42299 -37.58938 1.000 65.96915  ? 201 GLY   A CA  1 
ATOM   1584 C  C   . GLY   A 1 204 ? -8.26510  36.65113 -38.48911 1.000 71.81038  ? 201 GLY   A C   1 
ATOM   1585 O  O   . GLY   A 1 204 ? -7.03862  36.71131 -38.34793 1.000 73.78634  ? 201 GLY   A O   1 
ATOM   1586 N  N   . VAL   A 1 205 ? -8.85078  35.90681 -39.43096 1.000 68.43183  ? 202 VAL   A N   1 
ATOM   1587 C  CA  . VAL   A 1 205 ? -8.07797  35.02568 -40.30193 1.000 65.70540  ? 202 VAL   A CA  1 
ATOM   1588 C  C   . VAL   A 1 205 ? -7.04988  35.80782 -41.10801 1.000 70.98363  ? 202 VAL   A C   1 
ATOM   1589 O  O   . VAL   A 1 205 ? -5.96300  35.29608 -41.40930 1.000 68.99813  ? 202 VAL   A O   1 
ATOM   1590 C  CB  . VAL   A 1 205 ? -9.03304  34.23422 -41.21699 1.000 69.32737  ? 202 VAL   A CB  1 
ATOM   1591 C  CG1 . VAL   A 1 205 ? -8.26353  33.24747 -42.09178 1.000 55.08154  ? 202 VAL   A CG1 1 
ATOM   1592 C  CG2 . VAL   A 1 205 ? -10.08426 33.52129 -40.37937 1.000 70.36638  ? 202 VAL   A CG2 1 
ATOM   1593 N  N   . GLU   A 1 206 ? -7.36481  37.05237 -41.47009 1.000 69.43509  ? 203 GLU   A N   1 
ATOM   1594 C  CA  . GLU   A 1 206 ? -6.43203  37.84677 -42.26043 1.000 73.90718  ? 203 GLU   A CA  1 
ATOM   1595 C  C   . GLU   A 1 206 ? -5.19647  38.25086 -41.46725 1.000 65.94273  ? 203 GLU   A C   1 
ATOM   1596 O  O   . GLU   A 1 206 ? -4.19504  38.65747 -42.06590 1.000 67.78633  ? 203 GLU   A O   1 
ATOM   1597 C  CB  . GLU   A 1 206 ? -7.14062  39.08165 -42.81608 1.000 80.00061  ? 203 GLU   A CB  1 
ATOM   1598 C  CG  . GLU   A 1 206 ? -8.34512  38.74819 -43.68677 1.000 87.70099  ? 203 GLU   A CG  1 
ATOM   1599 C  CD  . GLU   A 1 206 ? -9.17373  39.96839 -44.03571 1.000 106.65626 ? 203 GLU   A CD  1 
ATOM   1600 O  OE1 . GLU   A 1 206 ? -9.20323  40.91790 -43.22447 1.000 109.09947 ? 203 GLU   A OE1 1 
ATOM   1601 O  OE2 . GLU   A 1 206 ? -9.79198  39.98017 -45.12189 1.000 109.95688 ? 203 GLU   A OE2 1 
ATOM   1602 N  N   . ALA   A 1 207 ? -5.24496  38.15386 -40.14008 1.000 67.47367  ? 204 ALA   A N   1 
ATOM   1603 C  CA  . ALA   A 1 207 ? -4.09769  38.50566 -39.31657 1.000 65.54320  ? 204 ALA   A CA  1 
ATOM   1604 C  C   . ALA   A 1 207 ? -3.05485  37.39870 -39.24494 1.000 69.52035  ? 204 ALA   A C   1 
ATOM   1605 O  O   . ALA   A 1 207 ? -1.90147  37.67763 -38.90156 1.000 73.23007  ? 204 ALA   A O   1 
ATOM   1606 C  CB  . ALA   A 1 207 ? -4.55819  38.86581 -37.90332 1.000 65.50978  ? 204 ALA   A CB  1 
ATOM   1607 N  N   . VAL   A 1 208 ? -3.42583  36.15583 -39.54973 1.000 67.05729  ? 205 VAL   A N   1 
ATOM   1608 C  CA  . VAL   A 1 208 ? -2.51024  35.02628 -39.41776 1.000 62.06860  ? 205 VAL   A CA  1 
ATOM   1609 C  C   . VAL   A 1 208 ? -2.08962  34.43262 -40.75230 1.000 63.36295  ? 205 VAL   A C   1 
ATOM   1610 O  O   . VAL   A 1 208 ? -1.19425  33.57107 -40.76848 1.000 61.22602  ? 205 VAL   A O   1 
ATOM   1611 C  CB  . VAL   A 1 208 ? -3.10741  33.91759 -38.52703 1.000 63.45439  ? 205 VAL   A CB  1 
ATOM   1612 C  CG1 . VAL   A 1 208 ? -3.62808  34.50481 -37.22848 1.000 67.38772  ? 205 VAL   A CG1 1 
ATOM   1613 C  CG2 . VAL   A 1 208 ? -4.20578  33.18483 -39.27220 1.000 60.91079  ? 205 VAL   A CG2 1 
ATOM   1614 N  N   . MET   A 1 209 ? -2.68492  34.85366 -41.86541 1.000 66.18577  ? 206 MET   A N   1 
ATOM   1615 C  CA  . MET   A 1 209 ? -2.36474  34.30017 -43.17426 1.000 62.06843  ? 206 MET   A CA  1 
ATOM   1616 C  C   . MET   A 1 209 ? -1.82270  35.39658 -44.07801 1.000 65.84635  ? 206 MET   A C   1 
ATOM   1617 O  O   . MET   A 1 209 ? -2.30972  36.53286 -44.05018 1.000 66.70991  ? 206 MET   A O   1 
ATOM   1618 C  CB  . MET   A 1 209 ? -3.59484  33.66709 -43.83134 1.000 59.07733  ? 206 MET   A CB  1 
ATOM   1619 C  CG  . MET   A 1 209 ? -4.14521  32.46562 -43.09261 1.000 69.69963  ? 206 MET   A CG  1 
ATOM   1620 S  SD  . MET   A 1 209 ? -5.30859  31.50945 -44.08129 1.000 70.93374  ? 206 MET   A SD  1 
ATOM   1621 C  CE  . MET   A 1 209 ? -4.29925  31.12587 -45.50549 1.000 73.07330  ? 206 MET   A CE  1 
ATOM   1622 N  N   . TYR   A 1 210 ? -0.81767  35.05595 -44.88281 1.000 62.61869  ? 207 TYR   A N   1 
ATOM   1623 C  CA  . TYR   A 1 210 ? -0.30047  35.99952 -45.86202 1.000 67.16586  ? 207 TYR   A CA  1 
ATOM   1624 C  C   . TYR   A 1 210 ? 0.17746   35.22228 -47.08129 1.000 69.99773  ? 207 TYR   A C   1 
ATOM   1625 O  O   . TYR   A 1 210 ? 0.81599   34.17402 -46.94662 1.000 69.72915  ? 207 TYR   A O   1 
ATOM   1626 C  CB  . TYR   A 1 210 ? 0.83948   36.86112 -45.30271 1.000 63.06527  ? 207 TYR   A CB  1 
ATOM   1627 C  CG  . TYR   A 1 210 ? 1.40177   37.81518 -46.33482 1.000 67.77224  ? 207 TYR   A CG  1 
ATOM   1628 C  CD1 . TYR   A 1 210 ? 0.73366   38.99588 -46.64171 1.000 66.76210  ? 207 TYR   A CD1 1 
ATOM   1629 C  CD2 . TYR   A 1 210 ? 2.56940   37.52460 -47.03122 1.000 70.88700  ? 207 TYR   A CD2 1 
ATOM   1630 C  CE1 . TYR   A 1 210 ? 1.22214   39.87229 -47.59289 1.000 71.97127  ? 207 TYR   A CE1 1 
ATOM   1631 C  CE2 . TYR   A 1 210 ? 3.06586   38.39756 -47.99134 1.000 68.02978  ? 207 TYR   A CE2 1 
ATOM   1632 C  CZ  . TYR   A 1 210 ? 2.38618   39.57011 -48.26561 1.000 73.83206  ? 207 TYR   A CZ  1 
ATOM   1633 O  OH  . TYR   A 1 210 ? 2.86639   40.44542 -49.21454 1.000 81.29320  ? 207 TYR   A OH  1 
ATOM   1634 N  N   . MET   A 1 211 ? -0.15272  35.73513 -48.26648 1.000 65.70245  ? 208 MET   A N   1 
ATOM   1635 C  CA  . MET   A 1 211 ? 0.27050   35.15924 -49.53782 1.000 64.67794  ? 208 MET   A CA  1 
ATOM   1636 C  C   . MET   A 1 211 ? 1.31535   36.07828 -50.15806 1.000 67.76517  ? 208 MET   A C   1 
ATOM   1637 O  O   . MET   A 1 211 ? 1.05833   37.27167 -50.35497 1.000 73.24787  ? 208 MET   A O   1 
ATOM   1638 C  CB  . MET   A 1 211 ? -0.92422  34.98016 -50.47775 1.000 64.36073  ? 208 MET   A CB  1 
ATOM   1639 C  CG  . MET   A 1 211 ? -0.60646  34.28994 -51.80257 1.000 52.20234  ? 208 MET   A CG  1 
ATOM   1640 S  SD  . MET   A 1 211 ? -0.01015  32.60261 -51.59486 1.000 69.40158  ? 208 MET   A SD  1 
ATOM   1641 C  CE  . MET   A 1 211 ? 0.32433   32.14114 -53.28806 1.000 76.97155  ? 208 MET   A CE  1 
ATOM   1642 N  N   . GLY   A 1 212 ? 2.48796   35.52471 -50.46243 1.000 65.21897  ? 209 GLY   A N   1 
ATOM   1643 C  CA  . GLY   A 1 212 ? 3.56620   36.31961 -51.01756 1.000 65.70520  ? 209 GLY   A CA  1 
ATOM   1644 C  C   . GLY   A 1 212 ? 4.94869   35.73386 -50.80740 1.000 69.18716  ? 209 GLY   A C   1 
ATOM   1645 O  O   . GLY   A 1 212 ? 5.60455   35.32634 -51.76974 1.000 75.87083  ? 209 GLY   A O   1 
ATOM   1646 N  N   . THR   A 1 213 ? 5.41343   35.69258 -49.56299 1.000 68.03192  ? 210 THR   A N   1 
ATOM   1647 C  CA  . THR   A 1 213 ? 6.71425   35.12417 -49.24351 1.000 69.06518  ? 210 THR   A CA  1 
ATOM   1648 C  C   . THR   A 1 213 ? 6.56140   34.01428 -48.21520 1.000 67.38044  ? 210 THR   A C   1 
ATOM   1649 O  O   . THR   A 1 213 ? 5.59720   33.98433 -47.44480 1.000 61.82175  ? 210 THR   A O   1 
ATOM   1650 C  CB  . THR   A 1 213 ? 7.68855   36.18047 -48.70626 1.000 68.70352  ? 210 THR   A CB  1 
ATOM   1651 O  OG1 . THR   A 1 213 ? 7.09000   36.87127 -47.60273 1.000 69.44002  ? 210 THR   A OG1 1 
ATOM   1652 C  CG2 . THR   A 1 213 ? 8.05417   37.17683 -49.79605 1.000 89.55736  ? 210 THR   A CG2 1 
ATOM   1653 N  N   . LEU   A 1 214 ? 7.52509   33.09543 -48.21919 1.000 64.00812  ? 211 LEU   A N   1 
ATOM   1654 C  CA  . LEU   A 1 214 ? 7.58749   32.05171 -47.20807 1.000 62.77111  ? 211 LEU   A CA  1 
ATOM   1655 C  C   . LEU   A 1 214 ? 8.33027   32.48732 -45.95394 1.000 65.05599  ? 211 LEU   A C   1 
ATOM   1656 O  O   . LEU   A 1 214 ? 8.13766   31.88149 -44.89348 1.000 66.83918  ? 211 LEU   A O   1 
ATOM   1657 C  CB  . LEU   A 1 214 ? 8.26074   30.79892 -47.77730 1.000 59.68458  ? 211 LEU   A CB  1 
ATOM   1658 C  CG  . LEU   A 1 214 ? 7.60604   30.14635 -48.99275 1.000 56.48610  ? 211 LEU   A CG  1 
ATOM   1659 C  CD1 . LEU   A 1 214 ? 8.48098   29.02086 -49.52640 1.000 51.28447  ? 211 LEU   A CD1 1 
ATOM   1660 C  CD2 . LEU   A 1 214 ? 6.22236   29.63835 -48.63893 1.000 57.85730  ? 211 LEU   A CD2 1 
ATOM   1661 N  N   . SER   A 1 215 ? 9.16622   33.51663 -46.04743 1.000 70.69984  ? 212 SER   A N   1 
ATOM   1662 C  CA  . SER   A 1 215 ? 10.02272  33.92401 -44.94257 1.000 69.27976  ? 212 SER   A CA  1 
ATOM   1663 C  C   . SER   A 1 215 ? 9.27570   34.89410 -44.03523 1.000 69.50522  ? 212 SER   A C   1 
ATOM   1664 O  O   . SER   A 1 215 ? 8.83995   35.96229 -44.48020 1.000 66.63529  ? 212 SER   A O   1 
ATOM   1665 C  CB  . SER   A 1 215 ? 11.30226  34.56667 -45.47539 1.000 63.47416  ? 212 SER   A CB  1 
ATOM   1666 O  OG  . SER   A 1 215 ? 12.01163  35.22610 -44.44462 1.000 74.42037  ? 212 SER   A OG  1 
ATOM   1667 N  N   . TYR   A 1 216 ? 9.13179   34.51895 -42.76191 1.000 68.36166  ? 213 TYR   A N   1 
ATOM   1668 C  CA  . TYR   A 1 216 ? 8.60656   35.44973 -41.77023 1.000 71.55964  ? 213 TYR   A CA  1 
ATOM   1669 C  C   . TYR   A 1 216 ? 9.56293   36.61127 -41.54246 1.000 77.92763  ? 213 TYR   A C   1 
ATOM   1670 O  O   . TYR   A 1 216 ? 9.12092   37.73699 -41.28251 1.000 76.50101  ? 213 TYR   A O   1 
ATOM   1671 C  CB  . TYR   A 1 216 ? 8.33451   34.70724 -40.45949 1.000 63.05897  ? 213 TYR   A CB  1 
ATOM   1672 C  CG  . TYR   A 1 216 ? 7.42931   35.43342 -39.48630 1.000 64.36870  ? 213 TYR   A CG  1 
ATOM   1673 C  CD1 . TYR   A 1 216 ? 6.49654   36.36454 -39.92572 1.000 67.58398  ? 213 TYR   A CD1 1 
ATOM   1674 C  CD2 . TYR   A 1 216 ? 7.49418   35.16606 -38.12382 1.000 68.54444  ? 213 TYR   A CD2 1 
ATOM   1675 C  CE1 . TYR   A 1 216 ? 5.66713   37.02352 -39.03097 1.000 65.47105  ? 213 TYR   A CE1 1 
ATOM   1676 C  CE2 . TYR   A 1 216 ? 6.66875   35.81574 -37.22383 1.000 62.91632  ? 213 TYR   A CE2 1 
ATOM   1677 C  CZ  . TYR   A 1 216 ? 5.75712   36.74304 -37.68192 1.000 68.40119  ? 213 TYR   A CZ  1 
ATOM   1678 O  OH  . TYR   A 1 216 ? 4.93499   37.39101 -36.78770 1.000 68.51349  ? 213 TYR   A OH  1 
ATOM   1679 N  N   . GLU   A 1 217 ? 10.86998  36.35714 -41.64470 1.000 76.24255  ? 214 GLU   A N   1 
ATOM   1680 C  CA  . GLU   A 1 217 ? 11.85677  37.41530 -41.45847 1.000 79.51098  ? 214 GLU   A CA  1 
ATOM   1681 C  C   . GLU   A 1 217 ? 11.73427  38.46987 -42.54959 1.000 74.64669  ? 214 GLU   A C   1 
ATOM   1682 O  O   . GLU   A 1 217 ? 11.74630  39.67473 -42.27339 1.000 81.23009  ? 214 GLU   A O   1 
ATOM   1683 C  CB  . GLU   A 1 217 ? 13.26318  36.81790 -41.43921 1.000 71.92870  ? 214 GLU   A CB  1 
ATOM   1684 C  CG  . GLU   A 1 217 ? 13.61749  36.14339 -40.12229 1.000 92.75886  ? 214 GLU   A CG  1 
ATOM   1685 C  CD  . GLU   A 1 217 ? 13.55313  37.08629 -38.93566 1.000 104.56013 ? 214 GLU   A CD  1 
ATOM   1686 O  OE1 . GLU   A 1 217 ? 14.45095  37.94574 -38.80943 1.000 106.82776 ? 214 GLU   A OE1 1 
ATOM   1687 O  OE2 . GLU   A 1 217 ? 12.60632  36.96441 -38.12623 1.000 96.20229  ? 214 GLU   A OE2 1 
ATOM   1688 N  N   . GLN   A 1 218 ? 11.62513  38.02747 -43.80324 1.000 78.54717  ? 215 GLN   A N   1 
ATOM   1689 C  CA  . GLN   A 1 218 ? 11.46538  38.96065 -44.91166 1.000 80.49899  ? 215 GLN   A CA  1 
ATOM   1690 C  C   . GLN   A 1 218 ? 10.18959  39.77868 -44.76738 1.000 80.41880  ? 215 GLN   A C   1 
ATOM   1691 O  O   . GLN   A 1 218 ? 10.16263  40.96571 -45.11074 1.000 79.84572  ? 215 GLN   A O   1 
ATOM   1692 C  CB  . GLN   A 1 218 ? 11.46570  38.20118 -46.23643 1.000 76.51625  ? 215 GLN   A CB  1 
ATOM   1693 C  CG  . GLN   A 1 218 ? 11.44892  39.10072 -47.45767 1.000 86.33575  ? 215 GLN   A CG  1 
ATOM   1694 C  CD  . GLN   A 1 218 ? 12.67412  39.98882 -47.53767 1.000 91.83531  ? 215 GLN   A CD  1 
ATOM   1695 O  OE1 . GLN   A 1 218 ? 13.77915  39.57673 -47.18092 1.000 95.26295  ? 215 GLN   A OE1 1 
ATOM   1696 N  NE2 . GLN   A 1 218 ? 12.48389  41.21808 -48.00264 1.000 92.09496  ? 215 GLN   A NE2 1 
ATOM   1697 N  N   . PHE   A 1 219 ? 9.11779   39.15965 -44.26918 1.000 78.21116  ? 216 PHE   A N   1 
ATOM   1698 C  CA  . PHE   A 1 219 ? 7.88785   39.90648 -44.04008 1.000 74.47070  ? 216 PHE   A CA  1 
ATOM   1699 C  C   . PHE   A 1 219 ? 8.10010   40.99547 -42.99820 1.000 78.66469  ? 216 PHE   A C   1 
ATOM   1700 O  O   . PHE   A 1 219 ? 7.48987   42.06816 -43.08189 1.000 79.39470  ? 216 PHE   A O   1 
ATOM   1701 C  CB  . PHE   A 1 219 ? 6.77998   38.93748 -43.61952 1.000 75.38770  ? 216 PHE   A CB  1 
ATOM   1702 C  CG  . PHE   A 1 219 ? 5.41041   39.55121 -43.56903 1.000 73.28855  ? 216 PHE   A CG  1 
ATOM   1703 C  CD1 . PHE   A 1 219 ? 4.78541   39.97955 -44.72960 1.000 72.55269  ? 216 PHE   A CD1 1 
ATOM   1704 C  CD2 . PHE   A 1 219 ? 4.72780   39.65916 -42.36836 1.000 77.93141  ? 216 PHE   A CD2 1 
ATOM   1705 C  CE1 . PHE   A 1 219 ? 3.51716   40.53306 -44.69021 1.000 74.62715  ? 216 PHE   A CE1 1 
ATOM   1706 C  CE2 . PHE   A 1 219 ? 3.45853   40.20994 -42.32248 1.000 80.85192  ? 216 PHE   A CE2 1 
ATOM   1707 C  CZ  . PHE   A 1 219 ? 2.85305   40.64612 -43.48588 1.000 69.14012  ? 216 PHE   A CZ  1 
ATOM   1708 N  N   . LYS   A 1 220 ? 8.96120   40.73563 -42.01269 1.000 83.95303  ? 217 LYS   A N   1 
ATOM   1709 C  CA  . LYS   A 1 220 ? 9.29667   41.75076 -41.01925 1.000 81.24384  ? 217 LYS   A CA  1 
ATOM   1710 C  C   . LYS   A 1 220 ? 10.12205  42.87514 -41.63407 1.000 83.96329  ? 217 LYS   A C   1 
ATOM   1711 O  O   . LYS   A 1 220 ? 9.89693   44.05479 -41.33632 1.000 86.90238  ? 217 LYS   A O   1 
ATOM   1712 C  CB  . LYS   A 1 220 ? 10.03393  41.10397 -39.84724 1.000 71.36231  ? 217 LYS   A CB  1 
ATOM   1713 C  CG  . LYS   A 1 220 ? 9.16693   40.14214 -39.04788 1.000 74.82450  ? 217 LYS   A CG  1 
ATOM   1714 C  CD  . LYS   A 1 220 ? 9.94456   39.46883 -37.93024 1.000 77.85029  ? 217 LYS   A CD  1 
ATOM   1715 C  CE  . LYS   A 1 220 ? 9.03771   38.57131 -37.10104 1.000 72.59522  ? 217 LYS   A CE  1 
ATOM   1716 N  NZ  . LYS   A 1 220 ? 9.78090   37.82004 -36.05209 1.000 74.69783  ? 217 LYS   A NZ  1 
ATOM   1717 N  N   . LYS   A 1 221 ? 11.08130  42.52637 -42.49450 1.000 86.41256  ? 218 LYS   A N   1 
ATOM   1718 C  CA  . LYS   A 1 221 ? 11.92342  43.53525 -43.13178 1.000 84.02926  ? 218 LYS   A CA  1 
ATOM   1719 C  C   . LYS   A 1 221 ? 11.14657  44.32875 -44.17661 1.000 85.41627  ? 218 LYS   A C   1 
ATOM   1720 O  O   . LYS   A 1 221 ? 11.13783  45.56490 -44.14994 1.000 92.92947  ? 218 LYS   A O   1 
ATOM   1721 C  CB  . LYS   A 1 221 ? 13.15298  42.86979 -43.75418 1.000 78.94136  ? 218 LYS   A CB  1 
ATOM   1722 C  CG  . LYS   A 1 221 ? 14.05876  42.19389 -42.73140 1.000 83.76556  ? 218 LYS   A CG  1 
ATOM   1723 C  CD  . LYS   A 1 221 ? 15.16385  41.38586 -43.39348 1.000 89.51903  ? 218 LYS   A CD  1 
ATOM   1724 C  CE  . LYS   A 1 221 ? 16.01051  40.66510 -42.35372 1.000 87.12023  ? 218 LYS   A CE  1 
ATOM   1725 N  NZ  . LYS   A 1 221 ? 17.05071  39.80224 -42.97925 1.000 86.04290  ? 218 LYS   A NZ  1 
ATOM   1726 N  N   . GLY   A 1 222 ? 10.49555  43.64619 -45.09998 1.000 89.10148  ? 219 GLY   A N   1 
ATOM   1727 C  CA  . GLY   A 1 222 ? 9.69333   44.30554 -46.11419 1.000 86.44422  ? 219 GLY   A CA  1 
ATOM   1728 C  C   . GLY   A 1 222 ? 9.60618   43.49522 -47.39487 1.000 83.72452  ? 219 GLY   A C   1 
ATOM   1729 O  O   . GLY   A 1 222 ? 10.52827  42.79287 -47.79856 1.000 83.77505  ? 219 GLY   A O   1 
ATOM   1730 N  N   . VAL   A 1 223 ? 8.45279   43.60075 -48.05815 1.000 85.43945  ? 220 VAL   A N   1 
ATOM   1731 C  CA  . VAL   A 1 223 ? 8.20832   42.93892 -49.33335 1.000 94.41823  ? 220 VAL   A CA  1 
ATOM   1732 C  C   . VAL   A 1 223 ? 7.71357   43.97793 -50.33144 1.000 95.76152  ? 220 VAL   A C   1 
ATOM   1733 O  O   . VAL   A 1 223 ? 7.14417   45.00321 -49.96126 1.000 97.49423  ? 220 VAL   A O   1 
ATOM   1734 C  CB  . VAL   A 1 223 ? 7.18971   41.78199 -49.20832 1.000 91.27820  ? 220 VAL   A CB  1 
ATOM   1735 C  CG1 . VAL   A 1 223 ? 7.74499   40.67687 -48.32429 1.000 81.29469  ? 220 VAL   A CG1 1 
ATOM   1736 C  CG2 . VAL   A 1 223 ? 5.86216   42.29695 -48.66384 1.000 82.69651  ? 220 VAL   A CG2 1 
ATOM   1737 N  N   . GLN   A 1 224 ? 7.93293   43.69088 -51.61418 1.000 102.54396 ? 221 GLN   A N   1 
ATOM   1738 C  CA  . GLN   A 1 224 ? 7.58832   44.62129 -52.68290 1.000 107.57080 ? 221 GLN   A CA  1 
ATOM   1739 C  C   . GLN   A 1 224 ? 6.16096   44.38787 -53.16393 1.000 104.23067 ? 221 GLN   A C   1 
ATOM   1740 O  O   . GLN   A 1 224 ? 5.77525   43.25424 -53.46797 1.000 104.06576 ? 221 GLN   A O   1 
ATOM   1741 C  CB  . GLN   A 1 224 ? 8.56860   44.49325 -53.84826 1.000 102.02348 ? 221 GLN   A CB  1 
ATOM   1742 C  CG  . GLN   A 1 224 ? 9.98454   44.90380 -53.48539 1.000 108.49318 ? 221 GLN   A CG  1 
ATOM   1743 C  CD  . GLN   A 1 224 ? 10.03354  46.23897 -52.76243 1.000 112.66670 ? 221 GLN   A CD  1 
ATOM   1744 O  OE1 . GLN   A 1 224 ? 10.55026  46.33599 -51.64832 1.000 106.45119 ? 221 GLN   A OE1 1 
ATOM   1745 N  NE2 . GLN   A 1 224 ? 9.49609   47.27617 -53.39511 1.000 115.54517 ? 221 GLN   A NE2 1 
ATOM   1746 N  N   . ILE   A 1 225 ? 5.38792   45.46700 -53.24349 1.000 108.80283 ? 222 ILE   A N   1 
ATOM   1747 C  CA  . ILE   A 1 225 ? 3.96750   45.39054 -53.57832 1.000 117.32635 ? 222 ILE   A CA  1 
ATOM   1748 C  C   . ILE   A 1 225 ? 3.60294   46.59986 -54.43579 1.000 123.27482 ? 222 ILE   A C   1 
ATOM   1749 O  O   . ILE   A 1 225 ? 4.06764   47.71528 -54.15996 1.000 128.40622 ? 222 ILE   A O   1 
ATOM   1750 C  CB  . ILE   A 1 225 ? 3.10617   45.29811 -52.30283 1.000 111.89461 ? 222 ILE   A CB  1 
ATOM   1751 C  CG1 . ILE   A 1 225 ? 1.62416   45.14262 -52.64670 1.000 120.25069 ? 222 ILE   A CG1 1 
ATOM   1752 C  CG2 . ILE   A 1 225 ? 3.31973   46.50394 -51.38820 1.000 105.38162 ? 222 ILE   A CG2 1 
ATOM   1753 C  CD1 . ILE   A 1 225 ? 0.75469   44.83862 -51.44183 1.000 109.23175 ? 222 ILE   A CD1 1 
ATOM   1754 N  N   . PRO   A 1 226 ? 2.82030   46.42792 -55.50048 1.000 122.11191 ? 223 PRO   A N   1 
ATOM   1755 C  CA  . PRO   A 1 226 ? 2.46064   47.58176 -56.33067 1.000 129.08937 ? 223 PRO   A CA  1 
ATOM   1756 C  C   . PRO   A 1 226 ? 1.59747   48.56402 -55.55612 1.000 136.60394 ? 223 PRO   A C   1 
ATOM   1757 O  O   . PRO   A 1 226 ? 0.68471   48.17434 -54.82303 1.000 134.18262 ? 223 PRO   A O   1 
ATOM   1758 C  CB  . PRO   A 1 226 ? 1.69404   46.95649 -57.49975 1.000 127.14241 ? 223 PRO   A CB  1 
ATOM   1759 C  CG  . PRO   A 1 226 ? 2.14186   45.54674 -57.53505 1.000 119.13890 ? 223 PRO   A CG  1 
ATOM   1760 C  CD  . PRO   A 1 226 ? 2.40608   45.15756 -56.11608 1.000 117.62342 ? 223 PRO   A CD  1 
ATOM   1761 N  N   . CYS   A 1 227 ? 1.91176   49.85118 -55.70143 1.000 144.25747 ? 224 CYS   A N   1 
ATOM   1762 C  CA  . CYS   A 1 227 ? 1.10047   50.91067 -55.12092 1.000 153.21983 ? 224 CYS   A CA  1 
ATOM   1763 C  C   . CYS   A 1 227 ? -0.02271  51.28406 -56.07505 1.000 160.12401 ? 224 CYS   A C   1 
ATOM   1764 O  O   . CYS   A 1 227 ? 0.04921   51.05395 -57.28685 1.000 148.44282 ? 224 CYS   A O   1 
ATOM   1765 C  CB  . CYS   A 1 227 ? 1.93292   52.15965 -54.80596 1.000 175.24709 ? 224 CYS   A CB  1 
ATOM   1766 S  SG  . CYS   A 1 227 ? 1.07088   53.41445 -53.78055 1.000 163.76772 ? 224 CYS   A SG  1 
ATOM   1767 N  N   . THR   A 1 228 ? -1.05904  51.89027 -55.51473 1.000 167.77189 ? 225 THR   A N   1 
ATOM   1768 C  CA  . THR   A 1 228 ? -2.15911  52.33499 -56.34852 1.000 168.35030 ? 225 THR   A CA  1 
ATOM   1769 C  C   . THR   A 1 228 ? -1.81820  53.60217 -57.13813 1.000 160.80520 ? 225 THR   A C   1 
ATOM   1770 O  O   . THR   A 1 228 ? -2.70166  54.21999 -57.74687 1.000 148.54503 ? 225 THR   A O   1 
ATOM   1771 C  CB  . THR   A 1 228 ? -3.42209  52.56833 -55.50770 1.000 184.09167 ? 225 THR   A CB  1 
ATOM   1772 O  OG1 . THR   A 1 228 ? -3.67088  53.97984 -55.41548 1.000 185.97385 ? 225 THR   A OG1 1 
ATOM   1773 C  CG2 . THR   A 1 228 ? -3.29974  51.96396 -54.08784 1.000 154.88401 ? 225 THR   A CG2 1 
ATOM   1774 N  N   . CYS   A 1 229 ? -0.54085  53.98960 -57.12379 1.000 162.16108 ? 226 CYS   A N   1 
ATOM   1775 C  CA  . CYS   A 1 229 ? -0.05864  55.15902 -57.84111 1.000 156.05373 ? 226 CYS   A CA  1 
ATOM   1776 C  C   . CYS   A 1 229 ? 0.74688   54.82281 -59.08596 1.000 153.50940 ? 226 CYS   A C   1 
ATOM   1777 O  O   . CYS   A 1 229 ? 0.75969   55.61817 -60.02810 1.000 154.48242 ? 226 CYS   A O   1 
ATOM   1778 C  CB  . CYS   A 1 229 ? 0.81108   56.02919 -56.92071 1.000 160.26801 ? 226 CYS   A CB  1 
ATOM   1779 S  SG  . CYS   A 1 229 ? 2.50056   55.40291 -56.67910 1.000 163.56624 ? 226 CYS   A SG  1 
ATOM   1780 N  N   . GLY   A 1 230 ? 1.42295   53.67617 -59.11146 1.000 148.05526 ? 227 GLY   A N   1 
ATOM   1781 C  CA  . GLY   A 1 230 ? 2.23524   53.28809 -60.24813 1.000 138.98035 ? 227 GLY   A CA  1 
ATOM   1782 C  C   . GLY   A 1 230 ? 3.66220   52.92944 -59.88372 1.000 135.72066 ? 227 GLY   A C   1 
ATOM   1783 O  O   . GLY   A 1 230 ? 4.48226   52.63428 -60.75910 1.000 120.74244 ? 227 GLY   A O   1 
ATOM   1784 N  N   . LYS   A 1 231 ? 3.97294   52.95417 -58.59261 1.000 140.98391 ? 228 LYS   A N   1 
ATOM   1785 C  CA  . LYS   A 1 231 ? 5.29788   52.61981 -58.09659 1.000 134.25064 ? 228 LYS   A CA  1 
ATOM   1786 C  C   . LYS   A 1 231 ? 5.23115   51.35189 -57.25597 1.000 135.01451 ? 228 LYS   A C   1 
ATOM   1787 O  O   . LYS   A 1 231 ? 4.19809   51.03617 -56.65981 1.000 135.63425 ? 228 LYS   A O   1 
ATOM   1788 C  CB  . LYS   A 1 231 ? 5.88169   53.76924 -57.26792 1.000 132.61588 ? 228 LYS   A CB  1 
ATOM   1789 N  N   . GLN   A 1 232 ? 6.34177   50.62052 -57.22066 1.000 124.51841 ? 229 GLN   A N   1 
ATOM   1790 C  CA  . GLN   A 1 232 ? 6.43266   49.39382 -56.43107 1.000 125.35397 ? 229 GLN   A CA  1 
ATOM   1791 C  C   . GLN   A 1 232 ? 6.73654   49.77834 -54.98788 1.000 125.46556 ? 229 GLN   A C   1 
ATOM   1792 O  O   . GLN   A 1 232 ? 7.87536   50.10372 -54.64457 1.000 119.15471 ? 229 GLN   A O   1 
ATOM   1793 C  CB  . GLN   A 1 232 ? 7.50013   48.46420 -56.99936 1.000 118.79191 ? 229 GLN   A CB  1 
ATOM   1794 C  CG  . GLN   A 1 232 ? 7.46406   47.04182 -56.44483 1.000 123.67544 ? 229 GLN   A CG  1 
ATOM   1795 C  CD  . GLN   A 1 232 ? 6.31855   46.21706 -57.01021 1.000 128.44360 ? 229 GLN   A CD  1 
ATOM   1796 O  OE1 . GLN   A 1 232 ? 5.65263   46.62890 -57.96052 1.000 127.44374 ? 229 GLN   A OE1 1 
ATOM   1797 N  NE2 . GLN   A 1 232 ? 6.08615   45.04438 -56.42718 1.000 125.93973 ? 229 GLN   A NE2 1 
ATOM   1798 N  N   . ALA   A 1 233 ? 5.71385   49.74668 -54.13650 1.000 125.45810 ? 230 ALA   A N   1 
ATOM   1799 C  CA  . ALA   A 1 233 ? 5.87883   50.10587 -52.73775 1.000 118.42737 ? 230 ALA   A CA  1 
ATOM   1800 C  C   . ALA   A 1 233 ? 6.41357   48.92067 -51.93524 1.000 113.26760 ? 230 ALA   A C   1 
ATOM   1801 O  O   . ALA   A 1 233 ? 6.56398   47.80403 -52.43802 1.000 112.80069 ? 230 ALA   A O   1 
ATOM   1802 C  CB  . ALA   A 1 233 ? 4.55585   50.59508 -52.14970 1.000 115.76102 ? 230 ALA   A CB  1 
ATOM   1803 N  N   . THR   A 1 234 ? 6.70132   49.17912 -50.66357 1.000 112.19606 ? 231 THR   A N   1 
ATOM   1804 C  CA  . THR   A 1 234 ? 7.23618   48.17831 -49.75194 1.000 107.16324 ? 231 THR   A CA  1 
ATOM   1805 C  C   . THR   A 1 234 ? 6.30484   48.04292 -48.55741 1.000 105.56574 ? 231 THR   A C   1 
ATOM   1806 O  O   . THR   A 1 234 ? 5.90485   49.04880 -47.96144 1.000 108.33469 ? 231 THR   A O   1 
ATOM   1807 C  CB  . THR   A 1 234 ? 8.64734   48.54936 -49.28474 1.000 103.45104 ? 231 THR   A CB  1 
ATOM   1808 O  OG1 . THR   A 1 234 ? 9.52038   48.62945 -50.41777 1.000 111.13334 ? 231 THR   A OG1 1 
ATOM   1809 C  CG2 . THR   A 1 234 ? 9.18204   47.50678 -48.31527 1.000 96.37964  ? 231 THR   A CG2 1 
ATOM   1810 N  N   . LYS   A 1 235 ? 5.96144   46.80549 -48.20958 1.000 100.23786 ? 232 LYS   A N   1 
ATOM   1811 C  CA  . LYS   A 1 235 ? 5.09185   46.53224 -47.07672 1.000 97.34630  ? 232 LYS   A CA  1 
ATOM   1812 C  C   . LYS   A 1 235 ? 5.88129   45.75398 -46.03557 1.000 93.01590  ? 232 LYS   A C   1 
ATOM   1813 O  O   . LYS   A 1 235 ? 6.64893   44.84787 -46.37476 1.000 86.46968  ? 232 LYS   A O   1 
ATOM   1814 C  CB  . LYS   A 1 235 ? 3.85070   45.73997 -47.51325 1.000 93.66091  ? 232 LYS   A CB  1 
ATOM   1815 C  CG  . LYS   A 1 235 ? 2.93682   45.31092 -46.37630 1.000 93.35953  ? 232 LYS   A CG  1 
ATOM   1816 C  CD  . LYS   A 1 235 ? 1.60626   44.78335 -46.89921 1.000 94.66122  ? 232 LYS   A CD  1 
ATOM   1817 C  CE  . LYS   A 1 235 ? 1.79587   43.62869 -47.87452 1.000 99.73403  ? 232 LYS   A CE  1 
ATOM   1818 N  NZ  . LYS   A 1 235 ? 0.49782   43.15991 -48.44477 1.000 103.50232 ? 232 LYS   A NZ  1 
ATOM   1819 N  N   . TYR   A 1 236 ? 5.67742   46.10208 -44.76712 1.000 91.51120  ? 233 TYR   A N   1 
ATOM   1820 C  CA  . TYR   A 1 236 ? 6.38290   45.46550 -43.66687 1.000 88.79241  ? 233 TYR   A CA  1 
ATOM   1821 C  C   . TYR   A 1 236 ? 5.43504   45.31731 -42.48633 1.000 86.12224  ? 233 TYR   A C   1 
ATOM   1822 O  O   . TYR   A 1 236 ? 4.43240   46.02831 -42.37183 1.000 86.27041  ? 233 TYR   A O   1 
ATOM   1823 C  CB  . TYR   A 1 236 ? 7.65382   46.24246 -43.26749 1.000 92.28221  ? 233 TYR   A CB  1 
ATOM   1824 C  CG  . TYR   A 1 236 ? 7.42632   47.55811 -42.54580 1.000 92.07654  ? 233 TYR   A CG  1 
ATOM   1825 C  CD1 . TYR   A 1 236 ? 7.28956   48.74823 -43.25008 1.000 93.46942  ? 233 TYR   A CD1 1 
ATOM   1826 C  CD2 . TYR   A 1 236 ? 7.37613   47.61195 -41.15697 1.000 96.20934  ? 233 TYR   A CD2 1 
ATOM   1827 C  CE1 . TYR   A 1 236 ? 7.09007   49.95287 -42.59140 1.000 97.45029  ? 233 TYR   A CE1 1 
ATOM   1828 C  CE2 . TYR   A 1 236 ? 7.17598   48.80979 -40.49097 1.000 98.90577  ? 233 TYR   A CE2 1 
ATOM   1829 C  CZ  . TYR   A 1 236 ? 7.03403   49.97659 -41.21256 1.000 102.99030 ? 233 TYR   A CZ  1 
ATOM   1830 O  OH  . TYR   A 1 236 ? 6.83627   51.16842 -40.55189 1.000 110.83639 ? 233 TYR   A OH  1 
ATOM   1831 N  N   . LEU   A 1 237 ? 5.76120   44.36889 -41.61234 1.000 81.13116  ? 234 LEU   A N   1 
ATOM   1832 C  CA  . LEU   A 1 237 ? 4.91942   44.03981 -40.47227 1.000 78.91619  ? 234 LEU   A CA  1 
ATOM   1833 C  C   . LEU   A 1 237 ? 5.25982   44.95580 -39.30136 1.000 84.16232  ? 234 LEU   A C   1 
ATOM   1834 O  O   . LEU   A 1 237 ? 6.43221   45.11140 -38.94388 1.000 80.06022  ? 234 LEU   A O   1 
ATOM   1835 C  CB  . LEU   A 1 237 ? 5.11993   42.57230 -40.08768 1.000 72.48058  ? 234 LEU   A CB  1 
ATOM   1836 C  CG  . LEU   A 1 237 ? 4.42631   42.01736 -38.84320 1.000 77.59063  ? 234 LEU   A CG  1 
ATOM   1837 C  CD1 . LEU   A 1 237 ? 2.91804   42.04021 -39.00850 1.000 76.48018  ? 234 LEU   A CD1 1 
ATOM   1838 C  CD2 . LEU   A 1 237 ? 4.91861   40.60636 -38.54776 1.000 67.49168  ? 234 LEU   A CD2 1 
ATOM   1839 N  N   . VAL   A 1 238 ? 4.23251   45.55414 -38.70852 1.000 81.85622  ? 235 VAL   A N   1 
ATOM   1840 C  CA  . VAL   A 1 238 ? 4.39188   46.49419 -37.60210 1.000 81.66381  ? 235 VAL   A CA  1 
ATOM   1841 C  C   . VAL   A 1 238 ? 4.12562   45.82749 -36.26339 1.000 87.22759  ? 235 VAL   A C   1 
ATOM   1842 O  O   . VAL   A 1 238 ? 4.95696   45.87831 -35.35728 1.000 91.85321  ? 235 VAL   A O   1 
ATOM   1843 C  CB  . VAL   A 1 238 ? 3.47493   47.72038 -37.80419 1.000 87.88814  ? 235 VAL   A CB  1 
ATOM   1844 C  CG1 . VAL   A 1 238 ? 3.52534   48.63425 -36.58485 1.000 80.39962  ? 235 VAL   A CG1 1 
ATOM   1845 C  CG2 . VAL   A 1 238 ? 3.87817   48.47142 -39.05445 1.000 88.36512  ? 235 VAL   A CG2 1 
ATOM   1846 N  N   . GLN   A 1 239 ? 2.96262   45.20083 -36.12058 1.000 84.07221  ? 236 GLN   A N   1 
ATOM   1847 C  CA  . GLN   A 1 239 ? 2.62836   44.46715 -34.91321 1.000 82.40605  ? 236 GLN   A CA  1 
ATOM   1848 C  C   . GLN   A 1 239 ? 1.94103   43.17037 -35.30716 1.000 83.80951  ? 236 GLN   A C   1 
ATOM   1849 O  O   . GLN   A 1 239 ? 1.21951   43.10785 -36.30689 1.000 81.13232  ? 236 GLN   A O   1 
ATOM   1850 C  CB  . GLN   A 1 239 ? 1.72176   45.28250 -33.97960 1.000 79.78860  ? 236 GLN   A CB  1 
ATOM   1851 C  CG  . GLN   A 1 239 ? 1.59856   44.70080 -32.57719 1.000 91.18210  ? 236 GLN   A CG  1 
ATOM   1852 C  CD  . GLN   A 1 239 ? 0.62900   45.47064 -31.69947 1.000 107.19198 ? 236 GLN   A CD  1 
ATOM   1853 O  OE1 . GLN   A 1 239 ? 0.13384   46.53167 -32.08144 1.000 108.59537 ? 236 GLN   A OE1 1 
ATOM   1854 N  NE2 . GLN   A 1 239 ? 0.35174   44.93584 -30.51410 1.000 101.18930 ? 236 GLN   A NE2 1 
ATOM   1855 N  N   . GLN   A 1 240 ? 2.17907   42.13205 -34.51125 1.000 81.06767  ? 237 GLN   A N   1 
ATOM   1856 C  CA  . GLN   A 1 240 ? 1.59525   40.81683 -34.75067 1.000 79.73551  ? 237 GLN   A CA  1 
ATOM   1857 C  C   . GLN   A 1 240 ? 1.27496   40.19998 -33.39884 1.000 75.16449  ? 237 GLN   A C   1 
ATOM   1858 O  O   . GLN   A 1 240 ? 2.18565   39.88470 -32.62624 1.000 82.43732  ? 237 GLN   A O   1 
ATOM   1859 C  CB  . GLN   A 1 240 ? 2.54235   39.92517 -35.55511 1.000 76.45058  ? 237 GLN   A CB  1 
ATOM   1860 C  CG  . GLN   A 1 240 ? 2.01622   38.52162 -35.81561 1.000 72.89663  ? 237 GLN   A CG  1 
ATOM   1861 C  CD  . GLN   A 1 240 ? 0.84975   38.49992 -36.78913 1.000 71.19563  ? 237 GLN   A CD  1 
ATOM   1862 O  OE1 . GLN   A 1 240 ? 1.02749   38.67503 -37.99527 1.000 75.92306  ? 237 GLN   A OE1 1 
ATOM   1863 N  NE2 . GLN   A 1 240 ? -0.35004  38.27205 -36.26897 1.000 69.51753  ? 237 GLN   A NE2 1 
ATOM   1864 N  N   . GLU   A 1 241 ? -0.01166  40.03616 -33.11156 1.000 68.73860  ? 238 GLU   A N   1 
ATOM   1865 C  CA  . GLU   A 1 241 ? -0.47932  39.42453 -31.87164 1.000 78.35005  ? 238 GLU   A CA  1 
ATOM   1866 C  C   . GLU   A 1 241 ? -1.28589  38.19131 -32.26468 1.000 77.45373  ? 238 GLU   A C   1 
ATOM   1867 O  O   . GLU   A 1 241 ? -2.48321  38.28723 -32.54038 1.000 84.29028  ? 238 GLU   A O   1 
ATOM   1868 C  CB  . GLU   A 1 241 ? -1.31195  40.41007 -31.04837 1.000 75.82229  ? 238 GLU   A CB  1 
ATOM   1869 C  CG  . GLU   A 1 241 ? -0.49304  41.46772 -30.32684 1.000 89.95498  ? 238 GLU   A CG  1 
ATOM   1870 C  CD  . GLU   A 1 241 ? -0.61149  41.36544 -28.81958 1.000 106.59723 ? 238 GLU   A CD  1 
ATOM   1871 O  OE1 . GLU   A 1 241 ? -1.64939  40.86599 -28.33597 1.000 115.65182 ? 238 GLU   A OE1 1 
ATOM   1872 O  OE2 . GLU   A 1 241 ? 0.33530   41.77884 -28.11776 1.000 117.94347 ? 238 GLU   A OE2 1 
ATOM   1873 N  N   . SER   A 1 242 ? -0.62892  37.03282 -32.29703 1.000 70.50902  ? 239 SER   A N   1 
ATOM   1874 C  CA  . SER   A 1 242 ? -1.28836  35.79736 -32.69782 1.000 65.30237  ? 239 SER   A CA  1 
ATOM   1875 C  C   . SER   A 1 242 ? -0.44257  34.62354 -32.23495 1.000 65.31672  ? 239 SER   A C   1 
ATOM   1876 O  O   . SER   A 1 242 ? 0.77151   34.77479 -32.05710 1.000 61.78229  ? 239 SER   A O   1 
ATOM   1877 C  CB  . SER   A 1 242 ? -1.48947  35.74401 -34.21905 1.000 66.03240  ? 239 SER   A CB  1 
ATOM   1878 O  OG  . SER   A 1 242 ? -0.24803  35.67082 -34.89597 1.000 60.56158  ? 239 SER   A OG  1 
ATOM   1879 N  N   . PRO   A 1 243 ? -1.04718  33.45114 -32.01617 1.000 63.82411  ? 240 PRO   A N   1 
ATOM   1880 C  CA  . PRO   A 1 243 ? -0.25462  32.29254 -31.57395 1.000 61.88168  ? 240 PRO   A CA  1 
ATOM   1881 C  C   . PRO   A 1 243 ? 0.60162   31.69217 -32.67587 1.000 67.60975  ? 240 PRO   A C   1 
ATOM   1882 O  O   . PRO   A 1 243 ? 1.53679   30.94115 -32.36883 1.000 63.08124  ? 240 PRO   A O   1 
ATOM   1883 C  CB  . PRO   A 1 243 ? -1.31795  31.29112 -31.09498 1.000 64.31005  ? 240 PRO   A CB  1 
ATOM   1884 C  CG  . PRO   A 1 243 ? -2.60943  32.06541 -31.03081 1.000 73.97790  ? 240 PRO   A CG  1 
ATOM   1885 C  CD  . PRO   A 1 243 ? -2.48585  33.14822 -32.05119 1.000 59.90236  ? 240 PRO   A CD  1 
ATOM   1886 N  N   . PHE   A 1 244 ? 0.30595   31.98389 -33.94129 1.000 61.08573  ? 241 PHE   A N   1 
ATOM   1887 C  CA  . PHE   A 1 244 ? 1.08502   31.47121 -35.06014 1.000 55.04886  ? 241 PHE   A CA  1 
ATOM   1888 C  C   . PHE   A 1 244 ? 0.87984   32.39770 -36.24991 1.000 62.75465  ? 241 PHE   A C   1 
ATOM   1889 O  O   . PHE   A 1 244 ? 0.01800   33.27948 -36.23215 1.000 65.74059  ? 241 PHE   A O   1 
ATOM   1890 C  CB  . PHE   A 1 244 ? 0.68495   30.03372 -35.40799 1.000 51.99438  ? 241 PHE   A CB  1 
ATOM   1891 C  CG  . PHE   A 1 244 ? -0.71551  29.91110 -35.93351 1.000 60.46932  ? 241 PHE   A CG  1 
ATOM   1892 C  CD1 . PHE   A 1 244 ? -1.78269  29.75118 -35.06686 1.000 57.75416  ? 241 PHE   A CD1 1 
ATOM   1893 C  CD2 . PHE   A 1 244 ? -0.96751  29.96953 -37.29613 1.000 58.25157  ? 241 PHE   A CD2 1 
ATOM   1894 C  CE1 . PHE   A 1 244 ? -3.07345  29.64919 -35.54784 1.000 55.93754  ? 241 PHE   A CE1 1 
ATOM   1895 C  CE2 . PHE   A 1 244 ? -2.25357  29.86944 -37.78190 1.000 56.09566  ? 241 PHE   A CE2 1 
ATOM   1896 C  CZ  . PHE   A 1 244 ? -3.30888  29.70863 -36.90683 1.000 52.67658  ? 241 PHE   A CZ  1 
ATOM   1897 N  N   . VAL   A 1 245 ? 1.68693   32.18591 -37.28901 1.000 59.58149  ? 242 VAL   A N   1 
ATOM   1898 C  CA  . VAL   A 1 245 ? 1.50206   32.84506 -38.57884 1.000 59.62908  ? 242 VAL   A CA  1 
ATOM   1899 C  C   . VAL   A 1 245 ? 1.74679   31.82469 -39.68247 1.000 61.97910  ? 242 VAL   A C   1 
ATOM   1900 O  O   . VAL   A 1 245 ? 2.66085   30.99760 -39.59168 1.000 55.00468  ? 242 VAL   A O   1 
ATOM   1901 C  CB  . VAL   A 1 245 ? 2.42008   34.07682 -38.75587 1.000 58.06697  ? 242 VAL   A CB  1 
ATOM   1902 C  CG1 . VAL   A 1 245 ? 2.01568   35.19311 -37.80221 1.000 56.43172  ? 242 VAL   A CG1 1 
ATOM   1903 C  CG2 . VAL   A 1 245 ? 3.88283   33.70069 -38.56645 1.000 60.21087  ? 242 VAL   A CG2 1 
ATOM   1904 N  N   . MET   A 1 246 ? 0.90691   31.87092 -40.71261 1.000 59.24322  ? 243 MET   A N   1 
ATOM   1905 C  CA  . MET   A 1 246 ? 1.03739   31.03085 -41.89506 1.000 55.99611  ? 243 MET   A CA  1 
ATOM   1906 C  C   . MET   A 1 246 ? 1.53894   31.88359 -43.05271 1.000 63.67573  ? 243 MET   A C   1 
ATOM   1907 O  O   . MET   A 1 246 ? 0.87935   32.85179 -43.44482 1.000 61.33459  ? 243 MET   A O   1 
ATOM   1908 C  CB  . MET   A 1 246 ? -0.29999  30.37526 -42.24201 1.000 57.83750  ? 243 MET   A CB  1 
ATOM   1909 C  CG  . MET   A 1 246 ? -0.27165  29.52472 -43.50030 1.000 66.13747  ? 243 MET   A CG  1 
ATOM   1910 S  SD  . MET   A 1 246 ? -1.82100  28.63682 -43.74271 1.000 66.37582  ? 243 MET   A SD  1 
ATOM   1911 C  CE  . MET   A 1 246 ? -1.41374  27.60382 -45.14676 1.000 63.75394  ? 243 MET   A CE  1 
ATOM   1912 N  N   . MET   A 1 247 ? 2.69958   31.52479 -43.59311 1.000 57.57615  ? 244 MET   A N   1 
ATOM   1913 C  CA  . MET   A 1 247 ? 3.29567   32.22280 -44.72529 1.000 57.58780  ? 244 MET   A CA  1 
ATOM   1914 C  C   . MET   A 1 247 ? 3.22873   31.32054 -45.95001 1.000 64.04289  ? 244 MET   A C   1 
ATOM   1915 O  O   . MET   A 1 247 ? 3.85016   30.25228 -45.97064 1.000 64.69123  ? 244 MET   A O   1 
ATOM   1916 C  CB  . MET   A 1 247 ? 4.73991   32.62490 -44.42655 1.000 56.89031  ? 244 MET   A CB  1 
ATOM   1917 C  CG  . MET   A 1 247 ? 4.91417   33.40825 -43.13604 1.000 51.13677  ? 244 MET   A CG  1 
ATOM   1918 S  SD  . MET   A 1 247 ? 4.22176   35.07133 -43.19943 1.000 57.80576  ? 244 MET   A SD  1 
ATOM   1919 C  CE  . MET   A 1 247 ? 5.05473   35.74477 -44.63725 1.000 69.68561  ? 244 MET   A CE  1 
ATOM   1920 N  N   . SER   A 1 248 ? 2.47277   31.74600 -46.96043 1.000 62.53045  ? 245 SER   A N   1 
ATOM   1921 C  CA  . SER   A 1 248 ? 2.29585   30.97658 -48.18070 1.000 58.68029  ? 245 SER   A CA  1 
ATOM   1922 C  C   . SER   A 1 248 ? 2.84835   31.73648 -49.38109 1.000 64.89210  ? 245 SER   A C   1 
ATOM   1923 O  O   . SER   A 1 248 ? 2.93619   32.96975 -49.37911 1.000 66.49287  ? 245 SER   A O   1 
ATOM   1924 C  CB  . SER   A 1 248 ? 0.82155   30.64201 -48.42894 1.000 59.90834  ? 245 SER   A CB  1 
ATOM   1925 O  OG  . SER   A 1 248 ? 0.30712   29.78966 -47.41996 1.000 63.58302  ? 245 SER   A OG  1 
ATOM   1926 N  N   . ALA   A 1 249 ? 3.20012   30.97778 -50.41020 1.000 65.91420  ? 246 ALA   A N   1 
ATOM   1927 C  CA  . ALA   A 1 249 ? 3.74276   31.50834 -51.65390 1.000 67.52044  ? 246 ALA   A CA  1 
ATOM   1928 C  C   . ALA   A 1 249 ? 3.66906   30.40689 -52.71132 1.000 62.84386  ? 246 ALA   A C   1 
ATOM   1929 O  O   . ALA   A 1 249 ? 3.61544   29.22239 -52.36276 1.000 63.21135  ? 246 ALA   A O   1 
ATOM   1930 C  CB  . ALA   A 1 249 ? 5.19300   31.98631 -51.47268 1.000 61.31974  ? 246 ALA   A CB  1 
ATOM   1931 N  N   . PRO   A 1 250 ? 3.64070   30.77084 -53.98993 1.000 64.38293  ? 247 PRO   A N   1 
ATOM   1932 C  CA  . PRO   A 1 250 ? 3.64072   29.74664 -55.04562 1.000 61.73196  ? 247 PRO   A CA  1 
ATOM   1933 C  C   . PRO   A 1 250 ? 4.87018   28.86517 -54.92702 1.000 59.54230  ? 247 PRO   A C   1 
ATOM   1934 O  O   . PRO   A 1 250 ? 5.95632   29.35910 -54.58732 1.000 64.37124  ? 247 PRO   A O   1 
ATOM   1935 C  CB  . PRO   A 1 250 ? 3.66259   30.57115 -56.34180 1.000 57.08516  ? 247 PRO   A CB  1 
ATOM   1936 C  CG  . PRO   A 1 250 ? 3.08382   31.88912 -55.95427 1.000 62.82851  ? 247 PRO   A CG  1 
ATOM   1937 C  CD  . PRO   A 1 250 ? 3.56292   32.12925 -54.55177 1.000 67.88979  ? 247 PRO   A CD  1 
ATOM   1938 N  N   . PRO   A 1 251 ? 4.73169   27.56366 -55.17346 1.000 59.82504  ? 248 PRO   A N   1 
ATOM   1939 C  CA  . PRO   A 1 251 ? 5.82900   26.62491 -54.90333 1.000 59.18751  ? 248 PRO   A CA  1 
ATOM   1940 C  C   . PRO   A 1 251 ? 7.14842   27.08055 -55.50526 1.000 61.31923  ? 248 PRO   A C   1 
ATOM   1941 O  O   . PRO   A 1 251 ? 7.23288   27.41711 -56.68654 1.000 71.49113  ? 248 PRO   A O   1 
ATOM   1942 C  CB  . PRO   A 1 251 ? 5.33942   25.32253 -55.54188 1.000 54.68107  ? 248 PRO   A CB  1 
ATOM   1943 C  CG  . PRO   A 1 251 ? 3.86578   25.41498 -55.47144 1.000 54.70689  ? 248 PRO   A CG  1 
ATOM   1944 C  CD  . PRO   A 1 251 ? 3.52612   26.87256 -55.65854 1.000 57.71210  ? 248 PRO   A CD  1 
ATOM   1945 N  N   . ALA   A 1 252 ? 8.18146   27.09329 -54.66947 1.000 69.23850  ? 249 ALA   A N   1 
ATOM   1946 C  CA  . ALA   A 1 252 ? 9.50826   27.52660 -55.06998 1.000 63.24757  ? 249 ALA   A CA  1 
ATOM   1947 C  C   . ALA   A 1 252 ? 10.52909  26.78285 -54.22722 1.000 68.26990  ? 249 ALA   A C   1 
ATOM   1948 O  O   . ALA   A 1 252 ? 10.25445  26.41286 -53.08225 1.000 67.76159  ? 249 ALA   A O   1 
ATOM   1949 C  CB  . ALA   A 1 252 ? 9.68184   29.04014 -54.90619 1.000 61.73404  ? 249 ALA   A CB  1 
ATOM   1950 N  N   . GLN   A 1 253 ? 11.70758  26.56232 -54.80559 1.000 69.51492  ? 250 GLN   A N   1 
ATOM   1951 C  CA  . GLN   A 1 253 ? 12.79366  25.94912 -54.05410 1.000 66.05555  ? 250 GLN   A CA  1 
ATOM   1952 C  C   . GLN   A 1 253 ? 13.14736  26.81764 -52.85571 1.000 65.14341  ? 250 GLN   A C   1 
ATOM   1953 O  O   . GLN   A 1 253 ? 13.37628  28.02357 -52.98938 1.000 65.94875  ? 250 GLN   A O   1 
ATOM   1954 C  CB  . GLN   A 1 253 ? 14.01217  25.75291 -54.95116 1.000 67.32184  ? 250 GLN   A CB  1 
ATOM   1955 C  CG  . GLN   A 1 253 ? 13.83838  24.63950 -55.96345 1.000 75.93912  ? 250 GLN   A CG  1 
ATOM   1956 C  CD  . GLN   A 1 253 ? 13.94715  23.26439 -55.34216 1.000 75.55780  ? 250 GLN   A CD  1 
ATOM   1957 O  OE1 . GLN   A 1 253 ? 14.73455  23.04571 -54.42082 1.000 70.73755  ? 250 GLN   A OE1 1 
ATOM   1958 N  NE2 . GLN   A 1 253 ? 13.15277  22.32517 -55.84539 1.000 71.72239  ? 250 GLN   A NE2 1 
ATOM   1959 N  N   . TYR   A 1 254 ? 13.17683  26.19816 -51.68021 1.000 66.28061  ? 251 TYR   A N   1 
ATOM   1960 C  CA  . TYR   A 1 254 ? 13.33253  26.91742 -50.42727 1.000 58.91903  ? 251 TYR   A CA  1 
ATOM   1961 C  C   . TYR   A 1 254 ? 14.15048  26.04582 -49.49014 1.000 70.47852  ? 251 TYR   A C   1 
ATOM   1962 O  O   . TYR   A 1 254 ? 14.08291  24.81497 -49.55311 1.000 70.85211  ? 251 TYR   A O   1 
ATOM   1963 C  CB  . TYR   A 1 254 ? 11.96777  27.24878 -49.81142 1.000 58.34696  ? 251 TYR   A CB  1 
ATOM   1964 C  CG  . TYR   A 1 254 ? 11.98751  28.28252 -48.70963 1.000 64.07228  ? 251 TYR   A CG  1 
ATOM   1965 C  CD1 . TYR   A 1 254 ? 12.21002  29.62475 -48.99390 1.000 58.66404  ? 251 TYR   A CD1 1 
ATOM   1966 C  CD2 . TYR   A 1 254 ? 11.76230  27.92120 -47.38533 1.000 67.73923  ? 251 TYR   A CD2 1 
ATOM   1967 C  CE1 . TYR   A 1 254 ? 12.21761  30.57775 -47.98798 1.000 69.07959  ? 251 TYR   A CE1 1 
ATOM   1968 C  CE2 . TYR   A 1 254 ? 11.76869  28.86650 -46.37255 1.000 63.04583  ? 251 TYR   A CE2 1 
ATOM   1969 C  CZ  . TYR   A 1 254 ? 11.99693  30.19232 -46.67893 1.000 69.42491  ? 251 TYR   A CZ  1 
ATOM   1970 O  OH  . TYR   A 1 254 ? 12.00372  31.13407 -45.67337 1.000 76.57393  ? 251 TYR   A OH  1 
ATOM   1971 N  N   . GLU   A 1 255 ? 14.92630  26.68617 -48.62331 1.000 68.20652  ? 252 GLU   A N   1 
ATOM   1972 C  CA  . GLU   A 1 255 ? 15.75676  25.97841 -47.65957 1.000 70.46711  ? 252 GLU   A CA  1 
ATOM   1973 C  C   . GLU   A 1 255 ? 15.14860  26.12954 -46.27255 1.000 74.11687  ? 252 GLU   A C   1 
ATOM   1974 O  O   . GLU   A 1 255 ? 15.06372  27.24381 -45.74537 1.000 72.68864  ? 252 GLU   A O   1 
ATOM   1975 C  CB  . GLU   A 1 255 ? 17.19473  26.49667 -47.67681 1.000 78.00099  ? 252 GLU   A CB  1 
ATOM   1976 C  CG  . GLU   A 1 255 ? 18.18203  25.53690 -47.02496 1.000 90.20502  ? 252 GLU   A CG  1 
ATOM   1977 C  CD  . GLU   A 1 255 ? 19.50400  26.19045 -46.67573 1.000 103.36781 ? 252 GLU   A CD  1 
ATOM   1978 O  OE1 . GLU   A 1 255 ? 19.55112  27.43599 -46.58443 1.000 102.90859 ? 252 GLU   A OE1 1 
ATOM   1979 O  OE2 . GLU   A 1 255 ? 20.49554  25.45421 -46.48443 1.000 107.92252 ? 252 GLU   A OE2 1 
ATOM   1980 N  N   . LEU   A 1 256 ? 14.71871  25.01209 -45.69446 1.000 71.87573  ? 253 LEU   A N   1 
ATOM   1981 C  CA  . LEU   A 1 256 ? 14.21430  24.98885 -44.32963 1.000 71.00513  ? 253 LEU   A CA  1 
ATOM   1982 C  C   . LEU   A 1 256 ? 15.35085  24.63182 -43.38325 1.000 70.24184  ? 253 LEU   A C   1 
ATOM   1983 O  O   . LEU   A 1 256 ? 16.01476  23.60563 -43.56127 1.000 74.84410  ? 253 LEU   A O   1 
ATOM   1984 C  CB  . LEU   A 1 256 ? 13.07533  23.97880 -44.18508 1.000 63.84219  ? 253 LEU   A CB  1 
ATOM   1985 C  CG  . LEU   A 1 256 ? 11.79892  24.25098 -44.97804 1.000 59.75376  ? 253 LEU   A CG  1 
ATOM   1986 C  CD1 . LEU   A 1 256 ? 10.89883  23.03180 -44.97031 1.000 57.27201  ? 253 LEU   A CD1 1 
ATOM   1987 C  CD2 . LEU   A 1 256 ? 11.07430  25.44668 -44.39906 1.000 59.57411  ? 253 LEU   A CD2 1 
ATOM   1988 N  N   . LYS   A 1 257 ? 15.57092  25.47606 -42.38149 1.000 66.99756  ? 254 LYS   A N   1 
ATOM   1989 C  CA  . LYS   A 1 257 ? 16.61489  25.26194 -41.39046 1.000 66.98443  ? 254 LYS   A CA  1 
ATOM   1990 C  C   . LYS   A 1 257 ? 15.96709  24.80376 -40.09198 1.000 67.01883  ? 254 LYS   A C   1 
ATOM   1991 O  O   . LYS   A 1 257 ? 14.99014  25.40685 -39.63435 1.000 64.26046  ? 254 LYS   A O   1 
ATOM   1992 C  CB  . LYS   A 1 257 ? 17.43381  26.53657 -41.16641 1.000 65.22403  ? 254 LYS   A CB  1 
ATOM   1993 C  CG  . LYS   A 1 257 ? 18.04918  27.13579 -42.43375 1.000 80.95734  ? 254 LYS   A CG  1 
ATOM   1994 C  CD  . LYS   A 1 257 ? 19.51762  26.74310 -42.61036 1.000 86.43353  ? 254 LYS   A CD  1 
ATOM   1995 C  CE  . LYS   A 1 257 ? 19.68206  25.32765 -43.15196 1.000 99.65650  ? 254 LYS   A CE  1 
ATOM   1996 N  NZ  . LYS   A 1 257 ? 21.07766  25.04985 -43.59968 1.000 104.99989 ? 254 LYS   A NZ  1 
ATOM   1997 N  N   . HIS   A 1 258 ? 16.50982  23.73620 -39.51164 1.000 68.47297  ? 255 HIS   A N   1 
ATOM   1998 C  CA  . HIS   A 1 258 ? 15.95734  23.16765 -38.28875 1.000 70.39537  ? 255 HIS   A CA  1 
ATOM   1999 C  C   . HIS   A 1 258 ? 15.86837  24.21319 -37.18227 1.000 67.65591  ? 255 HIS   A C   1 
ATOM   2000 O  O   . HIS   A 1 258 ? 16.81390  24.96826 -36.94560 1.000 66.71479  ? 255 HIS   A O   1 
ATOM   2001 C  CB  . HIS   A 1 258 ? 16.81517  21.98481 -37.83890 1.000 69.34878  ? 255 HIS   A CB  1 
ATOM   2002 C  CG  . HIS   A 1 258 ? 16.58080  21.57285 -36.42100 1.000 68.51823  ? 255 HIS   A CG  1 
ATOM   2003 N  ND1 . HIS   A 1 258 ? 17.43144  21.91827 -35.39303 1.000 90.63300  ? 255 HIS   A ND1 1 
ATOM   2004 C  CD2 . HIS   A 1 258 ? 15.59212  20.83699 -35.86014 1.000 72.43616  ? 255 HIS   A CD2 1 
ATOM   2005 C  CE1 . HIS   A 1 258 ? 16.97494  21.41575 -34.25889 1.000 85.09089  ? 255 HIS   A CE1 1 
ATOM   2006 N  NE2 . HIS   A 1 258 ? 15.86031  20.75463 -34.51521 1.000 78.97410  ? 255 HIS   A NE2 1 
ATOM   2007 N  N   . GLY   A 1 259 ? 14.72037  24.25642 -36.50915 1.000 66.02693  ? 256 GLY   A N   1 
ATOM   2008 C  CA  . GLY   A 1 259 ? 14.51545  25.13855 -35.38156 1.000 54.91002  ? 256 GLY   A CA  1 
ATOM   2009 C  C   . GLY   A 1 259 ? 14.09528  26.55359 -35.71598 1.000 59.87888  ? 256 GLY   A C   1 
ATOM   2010 O  O   . GLY   A 1 259 ? 13.85151  27.33979 -34.79238 1.000 64.58570  ? 256 GLY   A O   1 
ATOM   2011 N  N   . THR   A 1 260 ? 13.98339  26.90584 -36.99418 1.000 64.49063  ? 257 THR   A N   1 
ATOM   2012 C  CA  . THR   A 1 260 ? 13.58004  28.24728 -37.39784 1.000 61.50735  ? 257 THR   A CA  1 
ATOM   2013 C  C   . THR   A 1 260 ? 12.12329  28.32625 -37.83158 1.000 61.38903  ? 257 THR   A C   1 
ATOM   2014 O  O   . THR   A 1 260 ? 11.64628  29.41860 -38.15246 1.000 62.90174  ? 257 THR   A O   1 
ATOM   2015 C  CB  . THR   A 1 260 ? 14.47300  28.75450 -38.53274 1.000 65.74691  ? 257 THR   A CB  1 
ATOM   2016 O  OG1 . THR   A 1 260 ? 14.38568  27.86002 -39.65065 1.000 64.64589  ? 257 THR   A OG1 1 
ATOM   2017 C  CG2 . THR   A 1 260 ? 15.91465  28.83772 -38.06575 1.000 68.24084  ? 257 THR   A CG2 1 
ATOM   2018 N  N   . PHE   A 1 261 ? 11.41788  27.19813 -37.86997 1.000 65.94770  ? 258 PHE   A N   1 
ATOM   2019 C  CA  . PHE   A 1 261 ? 10.01814  27.15263 -38.26790 1.000 63.00085  ? 258 PHE   A CA  1 
ATOM   2020 C  C   . PHE   A 1 261 ? 9.34357   26.01655 -37.51062 1.000 60.61338  ? 258 PHE   A C   1 
ATOM   2021 O  O   . PHE   A 1 261 ? 10.00426  25.16633 -36.90834 1.000 58.35312  ? 258 PHE   A O   1 
ATOM   2022 C  CB  . PHE   A 1 261 ? 9.87112   26.96070 -39.78137 1.000 56.98926  ? 258 PHE   A CB  1 
ATOM   2023 C  CG  . PHE   A 1 261 ? 10.28635  25.59662 -40.25661 1.000 57.90709  ? 258 PHE   A CG  1 
ATOM   2024 C  CD1 . PHE   A 1 261 ? 11.62596  25.25774 -40.34276 1.000 54.44250  ? 258 PHE   A CD1 1 
ATOM   2025 C  CD2 . PHE   A 1 261 ? 9.33725   24.64641 -40.59814 1.000 59.61138  ? 258 PHE   A CD2 1 
ATOM   2026 C  CE1 . PHE   A 1 261 ? 12.01211  24.00096 -40.76768 1.000 59.29528  ? 258 PHE   A CE1 1 
ATOM   2027 C  CE2 . PHE   A 1 261 ? 9.71765   23.38647 -41.02378 1.000 57.69460  ? 258 PHE   A CE2 1 
ATOM   2028 C  CZ  . PHE   A 1 261 ? 11.05709  23.06429 -41.10862 1.000 60.71169  ? 258 PHE   A CZ  1 
ATOM   2029 N  N   . THR   A 1 262 ? 8.01207   25.99793 -37.55630 1.000 58.47901  ? 259 THR   A N   1 
ATOM   2030 C  CA  . THR   A 1 262 ? 7.25877   24.92440 -36.91384 1.000 52.77677  ? 259 THR   A CA  1 
ATOM   2031 C  C   . THR   A 1 262 ? 7.02411   23.75842 -37.87151 1.000 58.64902  ? 259 THR   A C   1 
ATOM   2032 O  O   . THR   A 1 262 ? 7.46969   22.63488 -37.61124 1.000 56.43248  ? 259 THR   A O   1 
ATOM   2033 C  CB  . THR   A 1 262 ? 5.92528   25.45502 -36.37772 1.000 54.43202  ? 259 THR   A CB  1 
ATOM   2034 O  OG1 . THR   A 1 262 ? 6.16308   26.57450 -35.51591 1.000 60.10356  ? 259 THR   A OG1 1 
ATOM   2035 C  CG2 . THR   A 1 262 ? 5.21417   24.37327 -35.59550 1.000 43.61375  ? 259 THR   A CG2 1 
ATOM   2036 N  N   . CYS   A 1 263 ? 6.32988   24.01196 -38.98130 1.000 52.33905  ? 260 CYS   A N   1 
ATOM   2037 C  CA  . CYS   A 1 263 ? 6.09321   22.99319 -39.99497 1.000 49.76470  ? 260 CYS   A CA  1 
ATOM   2038 C  C   . CYS   A 1 263 ? 5.86058   23.66725 -41.34157 1.000 56.09174  ? 260 CYS   A C   1 
ATOM   2039 O  O   . CYS   A 1 263 ? 5.65856   24.88218 -41.42763 1.000 51.45441  ? 260 CYS   A O   1 
ATOM   2040 C  CB  . CYS   A 1 263 ? 4.91229   22.09722 -39.61474 1.000 43.07448  ? 260 CYS   A CB  1 
ATOM   2041 S  SG  . CYS   A 1 263 ? 3.36711   22.99149 -39.37186 1.000 53.23673  ? 260 CYS   A SG  1 
ATOM   2042 N  N   . ALA   A 1 264 ? 5.87498   22.85954 -42.40227 1.000 53.00091  ? 261 ALA   A N   1 
ATOM   2043 C  CA  . ALA   A 1 264 ? 5.80371   23.40041 -43.75059 1.000 52.73956  ? 261 ALA   A CA  1 
ATOM   2044 C  C   . ALA   A 1 264 ? 5.13445   22.40235 -44.68653 1.000 57.12894  ? 261 ALA   A C   1 
ATOM   2045 O  O   . ALA   A 1 264 ? 5.11191   21.19404 -44.43279 1.000 52.27015  ? 261 ALA   A O   1 
ATOM   2046 C  CB  . ALA   A 1 264 ? 7.19749   23.76756 -44.27361 1.000 48.12137  ? 261 ALA   A CB  1 
ATOM   2047 N  N   . SER   A 1 265 ? 4.60185   22.93051 -45.78747 1.000 57.68147  ? 262 SER   A N   1 
ATOM   2048 C  CA  . SER   A 1 265 ? 3.95557   22.13829 -46.82568 1.000 55.55955  ? 262 SER   A CA  1 
ATOM   2049 C  C   . SER   A 1 265 ? 4.82915   22.11964 -48.06877 1.000 56.44433  ? 262 SER   A C   1 
ATOM   2050 O  O   . SER   A 1 265 ? 5.18433   23.17754 -48.59764 1.000 58.42747  ? 262 SER   A O   1 
ATOM   2051 C  CB  . SER   A 1 265 ? 2.57990   22.70479 -47.18511 1.000 52.07443  ? 262 SER   A CB  1 
ATOM   2052 O  OG  . SER   A 1 265 ? 1.73919   22.77601 -46.05289 1.000 70.63935  ? 262 SER   A OG  1 
ATOM   2053 N  N   . GLU   A 1 266 ? 5.14588   20.92286 -48.54590 1.000 50.46482  ? 263 GLU   A N   1 
ATOM   2054 C  CA  . GLU   A 1 266 ? 5.89557   20.74936 -49.77901 1.000 58.43678  ? 263 GLU   A CA  1 
ATOM   2055 C  C   . GLU   A 1 266 ? 4.93317   20.33702 -50.88358 1.000 63.53420  ? 263 GLU   A C   1 
ATOM   2056 O  O   . GLU   A 1 266 ? 4.11050   19.43637 -50.69054 1.000 61.90933  ? 263 GLU   A O   1 
ATOM   2057 C  CB  . GLU   A 1 266 ? 6.99826   19.70287 -49.60831 1.000 60.24136  ? 263 GLU   A CB  1 
ATOM   2058 C  CG  . GLU   A 1 266 ? 7.78633   19.41780 -50.88095 1.000 64.46613  ? 263 GLU   A CG  1 
ATOM   2059 C  CD  . GLU   A 1 266 ? 8.19891   17.96502 -51.00456 1.000 76.36346  ? 263 GLU   A CD  1 
ATOM   2060 O  OE1 . GLU   A 1 266 ? 9.20847   17.57874 -50.37477 1.000 72.49841  ? 263 GLU   A OE1 1 
ATOM   2061 O  OE2 . GLU   A 1 266 ? 7.51417   17.20931 -51.72691 1.000 82.73268  ? 263 GLU   A OE2 1 
ATOM   2062 N  N   . TYR   A 1 267 ? 5.03364   20.99997 -52.03414 1.000 57.69056  ? 264 TYR   A N   1 
ATOM   2063 C  CA  . TYR   A 1 267 ? 4.15954   20.73377 -53.16791 1.000 57.35984  ? 264 TYR   A CA  1 
ATOM   2064 C  C   . TYR   A 1 267 ? 5.00169   20.46215 -54.40454 1.000 62.51582  ? 264 TYR   A C   1 
ATOM   2065 O  O   . TYR   A 1 267 ? 5.84506   21.28217 -54.78236 1.000 59.33733  ? 264 TYR   A O   1 
ATOM   2066 C  CB  . TYR   A 1 267 ? 3.21036   21.90466 -53.42721 1.000 57.81071  ? 264 TYR   A CB  1 
ATOM   2067 C  CG  . TYR   A 1 267 ? 2.16970   21.60474 -54.48015 1.000 65.22753  ? 264 TYR   A CG  1 
ATOM   2068 C  CD1 . TYR   A 1 267 ? 1.03423   20.86608 -54.16991 1.000 56.89471  ? 264 TYR   A CD1 1 
ATOM   2069 C  CD2 . TYR   A 1 267 ? 2.33151   22.04041 -55.78884 1.000 63.21003  ? 264 TYR   A CD2 1 
ATOM   2070 C  CE1 . TYR   A 1 267 ? 0.08177   20.58476 -55.12980 1.000 61.76327  ? 264 TYR   A CE1 1 
ATOM   2071 C  CE2 . TYR   A 1 267 ? 1.38474   21.76143 -56.75595 1.000 59.26027  ? 264 TYR   A CE2 1 
ATOM   2072 C  CZ  . TYR   A 1 267 ? 0.26217   21.03311 -56.41965 1.000 60.35130  ? 264 TYR   A CZ  1 
ATOM   2073 O  OH  . TYR   A 1 267 ? -0.68758  20.75005 -57.37191 1.000 58.08835  ? 264 TYR   A OH  1 
ATOM   2074 N  N   . THR   A 1 268 ? 4.75951   19.31833 -55.03602 1.000 64.22165  ? 265 THR   A N   1 
ATOM   2075 C  CA  . THR   A 1 268 ? 5.47795   18.89892 -56.23192 1.000 60.96592  ? 265 THR   A CA  1 
ATOM   2076 C  C   . THR   A 1 268 ? 4.46748   18.63086 -57.33666 1.000 64.73555  ? 265 THR   A C   1 
ATOM   2077 O  O   . THR   A 1 268 ? 3.57359   17.79486 -57.17043 1.000 61.75036  ? 265 THR   A O   1 
ATOM   2078 C  CB  . THR   A 1 268 ? 6.31466   17.64868 -55.95834 1.000 59.02254  ? 265 THR   A CB  1 
ATOM   2079 O  OG1 . THR   A 1 268 ? 7.22696   17.90934 -54.88519 1.000 74.40870  ? 265 THR   A OG1 1 
ATOM   2080 C  CG2 . THR   A 1 268 ? 7.09820   17.25741 -57.19362 1.000 65.74739  ? 265 THR   A CG2 1 
ATOM   2081 N  N   . GLY   A 1 269 ? 4.60002   19.34753 -58.45412 1.000 66.19211  ? 266 GLY   A N   1 
ATOM   2082 C  CA  . GLY   A 1 269 ? 3.74417   19.14120 -59.59780 1.000 55.42193  ? 266 GLY   A CA  1 
ATOM   2083 C  C   . GLY   A 1 269 ? 3.26203   20.45584 -60.16412 1.000 59.76166  ? 266 GLY   A C   1 
ATOM   2084 O  O   . GLY   A 1 269 ? 3.84500   21.51927 -59.90635 1.000 63.23712  ? 266 GLY   A O   1 
ATOM   2085 N  N   . ASN   A 1 270 ? 2.18470   20.38287 -60.93359 1.000 58.36204  ? 267 ASN   A N   1 
ATOM   2086 C  CA  . ASN   A 1 270 ? 1.62713   21.53180 -61.62927 1.000 67.27499  ? 267 ASN   A CA  1 
ATOM   2087 C  C   . ASN   A 1 270 ? 0.48508   22.13642 -60.82497 1.000 60.47780  ? 267 ASN   A C   1 
ATOM   2088 O  O   . ASN   A 1 270 ? 0.00619   21.56469 -59.84342 1.000 61.59233  ? 267 ASN   A O   1 
ATOM   2089 C  CB  . ASN   A 1 270 ? 1.12315   21.13070 -63.01817 1.000 68.61781  ? 267 ASN   A CB  1 
ATOM   2090 C  CG  . ASN   A 1 270 ? 2.15388   20.36639 -63.80999 1.000 71.56286  ? 267 ASN   A CG  1 
ATOM   2091 O  OD1 . ASN   A 1 270 ? 3.29254   20.80781 -63.95672 1.000 71.23122  ? 267 ASN   A OD1 1 
ATOM   2092 N  ND2 . ASN   A 1 270 ? 1.76210   19.20456 -64.32261 1.000 77.44524  ? 267 ASN   A ND2 1 
ATOM   2093 N  N   . TYR   A 1 271 ? 0.05891   23.32106 -61.25363 1.000 56.58587  ? 268 TYR   A N   1 
ATOM   2094 C  CA  . TYR   A 1 271 ? -1.12719  23.94488 -60.68592 1.000 53.77118  ? 268 TYR   A CA  1 
ATOM   2095 C  C   . TYR   A 1 271 ? -2.32721  23.01688 -60.78513 1.000 60.64808  ? 268 TYR   A C   1 
ATOM   2096 O  O   . TYR   A 1 271 ? -2.66685  22.53824 -61.87058 1.000 71.51134  ? 268 TYR   A O   1 
ATOM   2097 C  CB  . TYR   A 1 271 ? -1.41720  25.26371 -61.39705 1.000 51.67748  ? 268 TYR   A CB  1 
ATOM   2098 C  CG  . TYR   A 1 271 ? -2.45105  26.12118 -60.70263 1.000 55.63620  ? 268 TYR   A CG  1 
ATOM   2099 C  CD1 . TYR   A 1 271 ? -2.39522  26.35588 -59.33638 1.000 55.53872  ? 268 TYR   A CD1 1 
ATOM   2100 C  CD2 . TYR   A 1 271 ? -3.48792  26.69802 -61.42267 1.000 59.99900  ? 268 TYR   A CD2 1 
ATOM   2101 C  CE1 . TYR   A 1 271 ? -3.34926  27.14226 -58.70787 1.000 59.15515  ? 268 TYR   A CE1 1 
ATOM   2102 C  CE2 . TYR   A 1 271 ? -4.44048  27.48434 -60.80598 1.000 60.08049  ? 268 TYR   A CE2 1 
ATOM   2103 C  CZ  . TYR   A 1 271 ? -4.36815  27.70379 -59.45138 1.000 58.71859  ? 268 TYR   A CZ  1 
ATOM   2104 O  OH  . TYR   A 1 271 ? -5.32185  28.48820 -58.84475 1.000 68.57775  ? 268 TYR   A OH  1 
ATOM   2105 N  N   . GLN   A 1 272 ? -2.94045  22.74144 -59.63658 1.000 58.30851  ? 269 GLN   A N   1 
ATOM   2106 C  CA  . GLN   A 1 272 ? -4.13505  21.91362 -59.50980 1.000 54.27888  ? 269 GLN   A CA  1 
ATOM   2107 C  C   . GLN   A 1 272 ? -3.90270  20.45128 -59.87104 1.000 52.55788  ? 269 GLN   A C   1 
ATOM   2108 O  O   . GLN   A 1 272 ? -4.86604  19.71933 -60.11242 1.000 59.14892  ? 269 GLN   A O   1 
ATOM   2109 C  CB  . GLN   A 1 272 ? -5.29113  22.49342 -60.33451 1.000 53.73847  ? 269 GLN   A CB  1 
ATOM   2110 C  CG  . GLN   A 1 272 ? -5.57293  23.94518 -59.98194 1.000 60.34689  ? 269 GLN   A CG  1 
ATOM   2111 C  CD  . GLN   A 1 272 ? -6.79287  24.50765 -60.67363 1.000 66.74146  ? 269 GLN   A CD  1 
ATOM   2112 O  OE1 . GLN   A 1 272 ? -6.97092  24.34156 -61.87964 1.000 79.46136  ? 269 GLN   A OE1 1 
ATOM   2113 N  NE2 . GLN   A 1 272 ? -7.64021  25.18841 -59.91080 1.000 62.91510  ? 269 GLN   A NE2 1 
ATOM   2114 N  N   . CYS   A 1 273 ? -2.64648  19.99564 -59.88011 1.000 54.70147  ? 270 CYS   A N   1 
ATOM   2115 C  CA  . CYS   A 1 273 ? -2.34997  18.57013 -60.03223 1.000 57.54743  ? 270 CYS   A CA  1 
ATOM   2116 C  C   . CYS   A 1 273 ? -0.93876  18.35278 -59.48261 1.000 62.76763  ? 270 CYS   A C   1 
ATOM   2117 O  O   . CYS   A 1 273 ? 0.04223   18.57620 -60.19662 1.000 58.71558  ? 270 CYS   A O   1 
ATOM   2118 C  CB  . CYS   A 1 273 ? -2.46164  18.14357 -61.48932 1.000 60.88933  ? 270 CYS   A CB  1 
ATOM   2119 S  SG  . CYS   A 1 273 ? -2.94546  16.41965 -61.80737 1.000 71.74449  ? 270 CYS   A SG  1 
ATOM   2120 N  N   . GLY   A 1 274 ? -0.85196  17.91370 -58.22780 1.000 60.30894  ? 271 GLY   A N   1 
ATOM   2121 C  CA  . GLY   A 1 274 ? 0.43977   17.73921 -57.58433 1.000 55.97634  ? 271 GLY   A CA  1 
ATOM   2122 C  C   . GLY   A 1 274 ? 0.31873   16.93862 -56.30631 1.000 58.94201  ? 271 GLY   A C   1 
ATOM   2123 O  O   . GLY   A 1 274 ? -0.78082  16.61142 -55.85017 1.000 64.27378  ? 271 GLY   A O   1 
ATOM   2124 N  N   . HIS   A 1 275 ? 1.48303   16.62242 -55.73548 1.000 58.11431  ? 272 HIS   A N   1 
ATOM   2125 C  CA  . HIS   A 1 275 ? 1.60169   15.85848 -54.49788 1.000 54.88319  ? 272 HIS   A CA  1 
ATOM   2126 C  C   . HIS   A 1 275 ? 2.05266   16.75240 -53.34443 1.000 64.42248  ? 272 HIS   A C   1 
ATOM   2127 O  O   . HIS   A 1 275 ? 2.93694   17.60048 -53.50831 1.000 57.94483  ? 272 HIS   A O   1 
ATOM   2128 C  CB  . HIS   A 1 275 ? 2.58889   14.69289 -54.66763 1.000 54.49769  ? 272 HIS   A CB  1 
ATOM   2129 C  CG  . HIS   A 1 275 ? 2.58447   13.72157 -53.52598 1.000 64.01295  ? 272 HIS   A CG  1 
ATOM   2130 N  ND1 . HIS   A 1 275 ? 1.50821   13.57998 -52.67618 1.000 75.12215  ? 272 HIS   A ND1 1 
ATOM   2131 C  CD2 . HIS   A 1 275 ? 3.52433   12.84871 -53.08907 1.000 67.71046  ? 272 HIS   A CD2 1 
ATOM   2132 C  CE1 . HIS   A 1 275 ? 1.78306   12.66194 -51.76682 1.000 77.04888  ? 272 HIS   A CE1 1 
ATOM   2133 N  NE2 . HIS   A 1 275 ? 2.99914   12.19986 -51.99593 1.000 70.25936  ? 272 HIS   A NE2 1 
ATOM   2134 N  N   . TYR   A 1 276 ? 1.43617   16.55828 -52.17947 1.000 64.42820  ? 273 TYR   A N   1 
ATOM   2135 C  CA  . TYR   A 1 276 ? 1.77614   17.27932 -50.95916 1.000 49.14945  ? 273 TYR   A CA  1 
ATOM   2136 C  C   . TYR   A 1 276 ? 2.60049   16.40543 -50.01933 1.000 55.81163  ? 273 TYR   A C   1 
ATOM   2137 O  O   . TYR   A 1 276 ? 2.34125   15.20637 -49.88396 1.000 60.80470  ? 273 TYR   A O   1 
ATOM   2138 C  CB  . TYR   A 1 276 ? 0.51205   17.72216 -50.22995 1.000 51.67293  ? 273 TYR   A CB  1 
ATOM   2139 C  CG  . TYR   A 1 276 ? 0.01550   19.10271 -50.56494 1.000 51.42673  ? 273 TYR   A CG  1 
ATOM   2140 C  CD1 . TYR   A 1 276 ? 0.69815   20.23041 -50.13843 1.000 49.41272  ? 273 TYR   A CD1 1 
ATOM   2141 C  CD2 . TYR   A 1 276 ? -1.16746  19.27841 -51.27132 1.000 46.81434  ? 273 TYR   A CD2 1 
ATOM   2142 C  CE1 . TYR   A 1 276 ? 0.22804   21.49974 -50.42713 1.000 53.37850  ? 273 TYR   A CE1 1 
ATOM   2143 C  CE2 . TYR   A 1 276 ? -1.64641  20.53936 -51.56169 1.000 47.60712  ? 273 TYR   A CE2 1 
ATOM   2144 C  CZ  . TYR   A 1 276 ? -0.94618  21.64695 -51.13837 1.000 49.09209  ? 273 TYR   A CZ  1 
ATOM   2145 O  OH  . TYR   A 1 276 ? -1.42586  22.90327 -51.43092 1.000 52.86448  ? 273 TYR   A OH  1 
ATOM   2146 N  N   . LYS   A 1 277 ? 3.59663   17.00895 -49.37200 1.000 58.12986  ? 274 LYS   A N   1 
ATOM   2147 C  CA  . LYS   A 1 277 ? 4.32447   16.37663 -48.27882 1.000 51.22598  ? 274 LYS   A CA  1 
ATOM   2148 C  C   . LYS   A 1 277 ? 4.43774   17.35543 -47.11814 1.000 57.34237  ? 274 LYS   A C   1 
ATOM   2149 O  O   . LYS   A 1 277 ? 4.42913   18.57362 -47.31504 1.000 57.13043  ? 274 LYS   A O   1 
ATOM   2150 C  CB  . LYS   A 1 277 ? 5.71809   15.89813 -48.69877 1.000 61.77660  ? 274 LYS   A CB  1 
ATOM   2151 C  CG  . LYS   A 1 277 ? 5.71334   14.60744 -49.49744 1.000 65.44772  ? 274 LYS   A CG  1 
ATOM   2152 C  CD  . LYS   A 1 277 ? 7.12819   14.12124 -49.77056 1.000 73.54431  ? 274 LYS   A CD  1 
ATOM   2153 C  CE  . LYS   A 1 277 ? 7.12432   12.90887 -50.68758 1.000 77.27615  ? 274 LYS   A CE  1 
ATOM   2154 N  NZ  . LYS   A 1 277 ? 8.41814   12.17189 -50.65184 1.000 88.77464  ? 274 LYS   A NZ  1 
ATOM   2155 N  N   . HIS   A 1 278 ? 4.54422   16.81264 -45.90542 1.000 56.92582  ? 275 HIS   A N   1 
ATOM   2156 C  CA  . HIS   A 1 278 ? 4.59239   17.60228 -44.67991 1.000 48.93749  ? 275 HIS   A CA  1 
ATOM   2157 C  C   . HIS   A 1 278 ? 5.98706   17.55632 -44.06922 1.000 51.86390  ? 275 HIS   A C   1 
ATOM   2158 O  O   . HIS   A 1 278 ? 6.51869   16.47206 -43.80641 1.000 54.33380  ? 275 HIS   A O   1 
ATOM   2159 C  CB  . HIS   A 1 278 ? 3.56691   17.09316 -43.66704 1.000 56.38444  ? 275 HIS   A CB  1 
ATOM   2160 C  CG  . HIS   A 1 278 ? 3.51988   17.89272 -42.40311 1.000 57.63709  ? 275 HIS   A CG  1 
ATOM   2161 N  ND1 . HIS   A 1 278 ? 2.90378   19.12229 -42.32280 1.000 54.90912  ? 275 HIS   A ND1 1 
ATOM   2162 C  CD2 . HIS   A 1 278 ? 4.00756   17.63448 -41.16617 1.000 51.36384  ? 275 HIS   A CD2 1 
ATOM   2163 C  CE1 . HIS   A 1 278 ? 3.01698   19.58930 -41.09211 1.000 52.20577  ? 275 HIS   A CE1 1 
ATOM   2164 N  NE2 . HIS   A 1 278 ? 3.68313   18.70572 -40.37080 1.000 50.70756  ? 275 HIS   A NE2 1 
ATOM   2165 N  N   . ILE   A 1 279 ? 6.56364   18.73262 -43.82409 1.000 51.16103  ? 276 ILE   A N   1 
ATOM   2166 C  CA  . ILE   A 1 279 ? 7.87482   18.86897 -43.19535 1.000 58.53482  ? 276 ILE   A CA  1 
ATOM   2167 C  C   . ILE   A 1 279 ? 7.68414   19.48302 -41.81531 1.000 58.73212  ? 276 ILE   A C   1 
ATOM   2168 O  O   . ILE   A 1 279 ? 7.04406   20.53267 -41.68219 1.000 58.73691  ? 276 ILE   A O   1 
ATOM   2169 C  CB  . ILE   A 1 279 ? 8.82117   19.73707 -44.04222 1.000 58.94655  ? 276 ILE   A CB  1 
ATOM   2170 C  CG1 . ILE   A 1 279 ? 8.82283   19.28040 -45.50257 1.000 62.13453  ? 276 ILE   A CG1 1 
ATOM   2171 C  CG2 . ILE   A 1 279 ? 10.22383  19.69159 -43.46670 1.000 56.89715  ? 276 ILE   A CG2 1 
ATOM   2172 C  CD1 . ILE   A 1 279 ? 9.37045   17.89615 -45.70844 1.000 68.29281  ? 276 ILE   A CD1 1 
ATOM   2173 N  N   . THR   A 1 280 ? 8.24091   18.83843 -40.79209 1.000 56.85601  ? 277 THR   A N   1 
ATOM   2174 C  CA  . THR   A 1 280 ? 8.14013   19.33055 -39.42540 1.000 61.48597  ? 277 THR   A CA  1 
ATOM   2175 C  C   . THR   A 1 280 ? 9.52382   19.39127 -38.78753 1.000 57.07544  ? 277 THR   A C   1 
ATOM   2176 O  O   . THR   A 1 280 ? 10.41107  18.59493 -39.10742 1.000 57.67014  ? 277 THR   A O   1 
ATOM   2177 C  CB  . THR   A 1 280 ? 7.19469   18.45604 -38.58053 1.000 54.34196  ? 277 THR   A CB  1 
ATOM   2178 O  OG1 . THR   A 1 280 ? 7.07152   19.01304 -37.26654 1.000 57.99794  ? 277 THR   A OG1 1 
ATOM   2179 C  CG2 . THR   A 1 280 ? 7.71252   17.02689 -38.48248 1.000 53.00763  ? 277 THR   A CG2 1 
ATOM   2180 N  N   . SER   A 1 281 ? 9.70052   20.35210 -37.88230 1.000 60.60099  ? 278 SER   A N   1 
ATOM   2181 C  CA  . SER   A 1 281 ? 10.98481  20.61703 -37.23184 1.000 61.01532  ? 278 SER   A CA  1 
ATOM   2182 C  C   . SER   A 1 281 ? 10.91939  20.14437 -35.78299 1.000 49.55901  ? 278 SER   A C   1 
ATOM   2183 O  O   . SER   A 1 281 ? 10.37304  20.83810 -34.92301 1.000 61.38360  ? 278 SER   A O   1 
ATOM   2184 C  CB  . SER   A 1 281 ? 11.33309  22.10128 -37.30707 1.000 58.06597  ? 278 SER   A CB  1 
ATOM   2185 O  OG  . SER   A 1 281 ? 12.59057  22.35506 -36.70558 1.000 63.82979  ? 278 SER   A OG  1 
ATOM   2186 N  N   . LYS   A 1 282 ? 11.46397  18.96529 -35.51906 1.000 55.11081  ? 279 LYS   A N   1 
ATOM   2187 C  CA  . LYS   A 1 282 ? 11.55189  18.40968 -34.16967 1.000 60.81295  ? 279 LYS   A CA  1 
ATOM   2188 C  C   . LYS   A 1 282 ? 13.00534  18.51167 -33.69948 1.000 61.42946  ? 279 LYS   A C   1 
ATOM   2189 O  O   . LYS   A 1 282 ? 13.59227  19.58836 -33.84415 1.000 57.54195  ? 279 LYS   A O   1 
ATOM   2190 C  CB  . LYS   A 1 282 ? 10.96936  17.00256 -34.16158 1.000 60.09429  ? 279 LYS   A CB  1 
ATOM   2191 C  CG  . LYS   A 1 282 ? 9.60185   16.90042 -34.80967 1.000 58.56795  ? 279 LYS   A CG  1 
ATOM   2192 C  CD  . LYS   A 1 282 ? 8.56640   17.68731 -34.02596 1.000 56.67871  ? 279 LYS   A CD  1 
ATOM   2193 C  CE  . LYS   A 1 282 ? 7.16041   17.22391 -34.35951 1.000 61.18383  ? 279 LYS   A CE  1 
ATOM   2194 N  NZ  . LYS   A 1 282 ? 6.95051   15.78700 -34.02384 1.000 59.40990  ? 279 LYS   A NZ  1 
ATOM   2195 N  N   . GLU   A 1 283 ? 13.60968  17.45335 -33.14520 1.000 61.51439  ? 280 GLU   A N   1 
ATOM   2196 C  CA  . GLU   A 1 283 ? 15.04160  17.50293 -32.86566 1.000 65.07895  ? 280 GLU   A CA  1 
ATOM   2197 C  C   . GLU   A 1 283 ? 15.84500  17.58339 -34.15759 1.000 69.26496  ? 280 GLU   A C   1 
ATOM   2198 O  O   . GLU   A 1 283 ? 16.93016  18.17350 -34.17684 1.000 73.88945  ? 280 GLU   A O   1 
ATOM   2199 C  CB  . GLU   A 1 283 ? 15.47158  16.29388 -32.02370 1.000 55.87088  ? 280 GLU   A CB  1 
ATOM   2200 C  CG  . GLU   A 1 283 ? 15.62291  14.98354 -32.78763 1.000 68.63539  ? 280 GLU   A CG  1 
ATOM   2201 C  CD  . GLU   A 1 283 ? 14.31636  14.23198 -32.96578 1.000 71.26163  ? 280 GLU   A CD  1 
ATOM   2202 O  OE1 . GLU   A 1 283 ? 13.23857  14.83629 -32.77404 1.000 68.77100  ? 280 GLU   A OE1 1 
ATOM   2203 O  OE2 . GLU   A 1 283 ? 14.37221  13.03318 -33.31480 1.000 66.48192  ? 280 GLU   A OE2 1 
ATOM   2204 N  N   . THR   A 1 284 ? 15.32151  17.00303 -35.23461 1.000 69.20252  ? 281 THR   A N   1 
ATOM   2205 C  CA  . THR   A 1 284 ? 15.85678  17.14699 -36.58128 1.000 64.95450  ? 281 THR   A CA  1 
ATOM   2206 C  C   . THR   A 1 284 ? 14.66568  17.40193 -37.50434 1.000 66.22282  ? 281 THR   A C   1 
ATOM   2207 O  O   . THR   A 1 284 ? 13.52939  17.56393 -37.04782 1.000 63.42284  ? 281 THR   A O   1 
ATOM   2208 C  CB  . THR   A 1 284 ? 16.68057  15.91157 -36.98344 1.000 62.72368  ? 281 THR   A CB  1 
ATOM   2209 O  OG1 . THR   A 1 284 ? 17.30561  16.12894 -38.25708 1.000 71.43178  ? 281 THR   A OG1 1 
ATOM   2210 C  CG2 . THR   A 1 284 ? 15.80339  14.67635 -37.06820 1.000 63.86236  ? 281 THR   A CG2 1 
ATOM   2211 N  N   . LEU   A 1 285 ? 14.91758  17.44027 -38.81034 1.000 66.24073  ? 282 LEU   A N   1 
ATOM   2212 C  CA  . LEU   A 1 285 ? 13.84843  17.64406 -39.78160 1.000 61.01629  ? 282 LEU   A CA  1 
ATOM   2213 C  C   . LEU   A 1 285 ? 13.24677  16.30288 -40.17400 1.000 63.32721  ? 282 LEU   A C   1 
ATOM   2214 O  O   . LEU   A 1 285 ? 13.96868  15.37287 -40.54576 1.000 68.34703  ? 282 LEU   A O   1 
ATOM   2215 C  CB  . LEU   A 1 285 ? 14.35766  18.37805 -41.01968 1.000 60.06139  ? 282 LEU   A CB  1 
ATOM   2216 C  CG  . LEU   A 1 285 ? 14.90829  19.78158 -40.78077 1.000 68.73399  ? 282 LEU   A CG  1 
ATOM   2217 C  CD1 . LEU   A 1 285 ? 15.34176  20.40247 -42.09699 1.000 67.56952  ? 282 LEU   A CD1 1 
ATOM   2218 C  CD2 . LEU   A 1 285 ? 13.86661  20.64676 -40.08429 1.000 61.37909  ? 282 LEU   A CD2 1 
ATOM   2219 N  N   . TYR   A 1 286 ? 11.92424  16.20823 -40.07502 1.000 60.41583  ? 283 TYR   A N   1 
ATOM   2220 C  CA  . TYR   A 1 286 ? 11.17808  15.01492 -40.44207 1.000 59.33306  ? 283 TYR   A CA  1 
ATOM   2221 C  C   . TYR   A 1 286 ? 10.25328  15.34067 -41.60463 1.000 65.13361  ? 283 TYR   A C   1 
ATOM   2222 O  O   . TYR   A 1 286 ? 9.68579   16.43683 -41.67240 1.000 65.10053  ? 283 TYR   A O   1 
ATOM   2223 C  CB  . TYR   A 1 286 ? 10.35438  14.48465 -39.26812 1.000 59.05283  ? 283 TYR   A CB  1 
ATOM   2224 C  CG  . TYR   A 1 286 ? 11.15875  13.76784 -38.20942 1.000 66.75102  ? 283 TYR   A CG  1 
ATOM   2225 C  CD1 . TYR   A 1 286 ? 11.44127  12.41254 -38.32456 1.000 58.85049  ? 283 TYR   A CD1 1 
ATOM   2226 C  CD2 . TYR   A 1 286 ? 11.62525  14.44259 -37.08548 1.000 63.50021  ? 283 TYR   A CD2 1 
ATOM   2227 C  CE1 . TYR   A 1 286 ? 12.17271  11.74980 -37.35343 1.000 68.05221  ? 283 TYR   A CE1 1 
ATOM   2228 C  CE2 . TYR   A 1 286 ? 12.35839  13.78777 -36.10926 1.000 56.27063  ? 283 TYR   A CE2 1 
ATOM   2229 C  CZ  . TYR   A 1 286 ? 12.62852  12.44110 -36.24841 1.000 66.33033  ? 283 TYR   A CZ  1 
ATOM   2230 O  OH  . TYR   A 1 286 ? 13.35679  11.77923 -35.28417 1.000 62.19566  ? 283 TYR   A OH  1 
ATOM   2231 N  N   . CYS   A 1 287 ? 10.11059  14.38582 -42.51845 1.000 62.86627  ? 284 CYS   A N   1 
ATOM   2232 C  CA  . CYS   A 1 287 ? 9.21548   14.50359 -43.66176 1.000 57.98801  ? 284 CYS   A CA  1 
ATOM   2233 C  C   . CYS   A 1 287 ? 8.16576   13.40591 -43.55977 1.000 59.51554  ? 284 CYS   A C   1 
ATOM   2234 O  O   . CYS   A 1 287 ? 8.50578   12.21774 -43.55692 1.000 60.90931  ? 284 CYS   A O   1 
ATOM   2235 C  CB  . CYS   A 1 287 ? 9.98895   14.40352 -44.97687 1.000 58.82000  ? 284 CYS   A CB  1 
ATOM   2236 S  SG  . CYS   A 1 287 ? 8.95970   14.47494 -46.45931 1.000 72.48260  ? 284 CYS   A SG  1 
ATOM   2237 N  N   . ILE   A 1 288 ? 6.89975   13.79977 -43.45490 1.000 54.87759  ? 285 ILE   A N   1 
ATOM   2238 C  CA  . ILE   A 1 288 ? 5.79043   12.86248 -43.32126 1.000 53.91292  ? 285 ILE   A CA  1 
ATOM   2239 C  C   . ILE   A 1 288 ? 4.99238   12.88567 -44.61513 1.000 57.32078  ? 285 ILE   A C   1 
ATOM   2240 O  O   . ILE   A 1 288 ? 4.46738   13.93387 -45.01323 1.000 58.13733  ? 285 ILE   A O   1 
ATOM   2241 C  CB  . ILE   A 1 288 ? 4.89718   13.20112 -42.11937 1.000 55.05956  ? 285 ILE   A CB  1 
ATOM   2242 C  CG1 . ILE   A 1 288 ? 5.72591   13.26762 -40.83804 1.000 51.27103  ? 285 ILE   A CG1 1 
ATOM   2243 C  CG2 . ILE   A 1 288 ? 3.79961   12.16042 -41.96937 1.000 50.92342  ? 285 ILE   A CG2 1 
ATOM   2244 C  CD1 . ILE   A 1 288 ? 4.91035   13.61396 -39.62018 1.000 50.09679  ? 285 ILE   A CD1 1 
ATOM   2245 N  N   . ASP   A 1 289 ? 4.91264   11.73294 -45.27358 1.000 56.90874  ? 286 ASP   A N   1 
ATOM   2246 C  CA  . ASP   A 1 289 ? 4.14725   11.54492 -46.50438 1.000 60.40413  ? 286 ASP   A CA  1 
ATOM   2247 C  C   . ASP   A 1 289 ? 3.13086   10.44338 -46.22315 1.000 59.75762  ? 286 ASP   A C   1 
ATOM   2248 O  O   . ASP   A 1 289 ? 3.38742   9.26436  -46.48087 1.000 56.54170  ? 286 ASP   A O   1 
ATOM   2249 C  CB  . ASP   A 1 289 ? 5.06115   11.19691 -47.68377 1.000 63.29300  ? 286 ASP   A CB  1 
ATOM   2250 C  CG  . ASP   A 1 289 ? 4.30321   11.05819 -48.99302 1.000 72.23982  ? 286 ASP   A CG  1 
ATOM   2251 O  OD1 . ASP   A 1 289 ? 3.10172   11.39675 -49.03141 1.000 72.35597  ? 286 ASP   A OD1 1 
ATOM   2252 O  OD2 . ASP   A 1 289 ? 4.91063   10.60552 -49.98706 1.000 80.61231  ? 286 ASP   A OD2 1 
ATOM   2253 N  N   . GLY   A 1 290 ? 1.98030   10.83304 -45.68076 1.000 55.99590  ? 287 GLY   A N   1 
ATOM   2254 C  CA  . GLY   A 1 290 ? 0.98027   9.87062  -45.26755 1.000 50.38659  ? 287 GLY   A CA  1 
ATOM   2255 C  C   . GLY   A 1 290 ? 1.48297   8.96956  -44.16048 1.000 59.05830  ? 287 GLY   A C   1 
ATOM   2256 O  O   . GLY   A 1 290 ? 1.71816   9.42690  -43.03764 1.000 59.72043  ? 287 GLY   A O   1 
ATOM   2257 N  N   . ALA   A 1 291 ? 1.65708   7.68722  -44.46251 1.000 59.58201  ? 288 ALA   A N   1 
ATOM   2258 C  CA  . ALA   A 1 291 ? 2.16329   6.73005  -43.48971 1.000 56.42031  ? 288 ALA   A CA  1 
ATOM   2259 C  C   . ALA   A 1 291 ? 3.67938   6.58026  -43.53375 1.000 63.09406  ? 288 ALA   A C   1 
ATOM   2260 O  O   . ALA   A 1 291 ? 4.23152   5.79240  -42.75949 1.000 67.85861  ? 288 ALA   A O   1 
ATOM   2261 C  CB  . ALA   A 1 291 ? 1.49872   5.36659  -43.70362 1.000 53.29810  ? 288 ALA   A CB  1 
ATOM   2262 N  N   . LEU   A 1 292 ? 4.36293   7.31520  -44.40552 1.000 64.07883  ? 289 LEU   A N   1 
ATOM   2263 C  CA  . LEU   A 1 292 ? 5.80001   7.17683  -44.58971 1.000 61.44650  ? 289 LEU   A CA  1 
ATOM   2264 C  C   . LEU   A 1 292 ? 6.52997   8.31457  -43.88951 1.000 69.56998  ? 289 LEU   A C   1 
ATOM   2265 O  O   . LEU   A 1 292 ? 6.08385   9.46572  -43.91978 1.000 70.83798  ? 289 LEU   A O   1 
ATOM   2266 C  CB  . LEU   A 1 292 ? 6.15672   7.16891  -46.07741 1.000 67.56619  ? 289 LEU   A CB  1 
ATOM   2267 C  CG  . LEU   A 1 292 ? 5.33416   6.23108  -46.96449 1.000 78.19836  ? 289 LEU   A CG  1 
ATOM   2268 C  CD1 . LEU   A 1 292 ? 5.65095   6.47173  -48.43408 1.000 69.23166  ? 289 LEU   A CD1 1 
ATOM   2269 C  CD2 . LEU   A 1 292 ? 5.56770   4.77280  -46.58688 1.000 66.75046  ? 289 LEU   A CD2 1 
ATOM   2270 N  N   . LEU   A 1 293 ? 7.65960   7.98651  -43.26553 1.000 68.36925  ? 290 LEU   A N   1 
ATOM   2271 C  CA  . LEU   A 1 293 ? 8.43866   8.94695  -42.49866 1.000 60.68805  ? 290 LEU   A CA  1 
ATOM   2272 C  C   . LEU   A 1 293 ? 9.89896   8.88206  -42.91984 1.000 64.91397  ? 290 LEU   A C   1 
ATOM   2273 O  O   . LEU   A 1 293 ? 10.45198  7.79484  -43.10604 1.000 66.65845  ? 290 LEU   A O   1 
ATOM   2274 C  CB  . LEU   A 1 293 ? 8.31372   8.68006  -40.99346 1.000 56.56127  ? 290 LEU   A CB  1 
ATOM   2275 C  CG  . LEU   A 1 293 ? 9.08693   9.60009  -40.04767 1.000 55.12571  ? 290 LEU   A CG  1 
ATOM   2276 C  CD1 . LEU   A 1 293 ? 8.72122   11.05332 -40.28148 1.000 64.11692  ? 290 LEU   A CD1 1 
ATOM   2277 C  CD2 . LEU   A 1 293 ? 8.80398   9.21864  -38.61509 1.000 48.41593  ? 290 LEU   A CD2 1 
ATOM   2278 N  N   . THR   A 1 294 ? 10.51686  10.05352 -43.07249 1.000 64.78407  ? 291 THR   A N   1 
ATOM   2279 C  CA  . THR   A 1 294 ? 11.92839  10.17332 -43.41385 1.000 67.46352  ? 291 THR   A CA  1 
ATOM   2280 C  C   . THR   A 1 294 ? 12.51994  11.33019 -42.62245 1.000 69.49148  ? 291 THR   A C   1 
ATOM   2281 O  O   . THR   A 1 294 ? 11.84599  12.33226 -42.36937 1.000 64.80724  ? 291 THR   A O   1 
ATOM   2282 C  CB  . THR   A 1 294 ? 12.17014  10.41969 -44.91568 1.000 59.93916  ? 291 THR   A CB  1 
ATOM   2283 O  OG1 . THR   A 1 294 ? 11.79326  11.76033 -45.25283 1.000 66.04855  ? 291 THR   A OG1 1 
ATOM   2284 C  CG2 . THR   A 1 294 ? 11.37605  9.44956  -45.76820 1.000 61.91750  ? 291 THR   A CG2 1 
ATOM   2285 N  N   . LYS   A 1 295 ? 13.78552  11.18579 -42.23204 1.000 66.77803  ? 292 LYS   A N   1 
ATOM   2286 C  CA  . LYS   A 1 295 ? 14.47802  12.19949 -41.45014 1.000 69.15361  ? 292 LYS   A CA  1 
ATOM   2287 C  C   . LYS   A 1 295 ? 15.73099  12.66963 -42.17701 1.000 69.47044  ? 292 LYS   A C   1 
ATOM   2288 O  O   . LYS   A 1 295 ? 16.35435  11.91506 -42.92791 1.000 76.65825  ? 292 LYS   A O   1 
ATOM   2289 C  CB  . LYS   A 1 295 ? 14.85836  11.67201 -40.05939 1.000 71.07599  ? 292 LYS   A CB  1 
ATOM   2290 C  CG  . LYS   A 1 295 ? 15.67759  10.39091 -40.08491 1.000 82.40467  ? 292 LYS   A CG  1 
ATOM   2291 C  CD  . LYS   A 1 295 ? 15.78085  9.77222  -38.70195 1.000 73.73036  ? 292 LYS   A CD  1 
ATOM   2292 C  CE  . LYS   A 1 295 ? 16.43837  10.72760 -37.72548 1.000 75.10902  ? 292 LYS   A CE  1 
ATOM   2293 N  NZ  . LYS   A 1 295 ? 16.56296  10.12609 -36.37123 1.000 86.79969  ? 292 LYS   A NZ  1 
ATOM   2294 N  N   . SER   A 1 296 ? 16.09140  13.92993 -41.94086 1.000 72.04644  ? 293 SER   A N   1 
ATOM   2295 C  CA  . SER   A 1 296 ? 17.28078  14.53359 -42.52550 1.000 70.86205  ? 293 SER   A CA  1 
ATOM   2296 C  C   . SER   A 1 296 ? 17.63176  15.77799 -41.72519 1.000 70.53246  ? 293 SER   A C   1 
ATOM   2297 O  O   . SER   A 1 296 ? 16.76026  16.40766 -41.12220 1.000 74.11504  ? 293 SER   A O   1 
ATOM   2298 C  CB  . SER   A 1 296 ? 17.06523  14.88897 -43.99957 1.000 75.41293  ? 293 SER   A CB  1 
ATOM   2299 O  OG  . SER   A 1 296 ? 16.06709  15.88438 -44.13161 1.000 78.62947  ? 293 SER   A OG  1 
ATOM   2300 N  N   . SER   A 1 297 ? 18.92033  16.12205 -41.72051 1.000 78.97003  ? 294 SER   A N   1 
ATOM   2301 C  CA  . SER   A 1 297 ? 19.36724  17.27547 -40.94547 1.000 75.70437  ? 294 SER   A CA  1 
ATOM   2302 C  C   . SER   A 1 297 ? 19.10421  18.58505 -41.68060 1.000 76.46116  ? 294 SER   A C   1 
ATOM   2303 O  O   . SER   A 1 297 ? 18.78469  19.59859 -41.04855 1.000 77.63168  ? 294 SER   A O   1 
ATOM   2304 C  CB  . SER   A 1 297 ? 20.84921  17.13501 -40.59549 1.000 65.91833  ? 294 SER   A CB  1 
ATOM   2305 O  OG  . SER   A 1 297 ? 21.64791  17.08206 -41.76206 1.000 93.49277  ? 294 SER   A OG  1 
ATOM   2306 N  N   . GLU   A 1 298 ? 19.23919  18.58777 -43.00371 1.000 77.31496  ? 295 GLU   A N   1 
ATOM   2307 C  CA  . GLU   A 1 298 ? 18.92501  19.74757 -43.82181 1.000 75.42905  ? 295 GLU   A CA  1 
ATOM   2308 C  C   . GLU   A 1 298 ? 17.80077  19.40798 -44.79219 1.000 76.02494  ? 295 GLU   A C   1 
ATOM   2309 O  O   . GLU   A 1 298 ? 17.48337  18.23750 -45.02533 1.000 74.45481  ? 295 GLU   A O   1 
ATOM   2310 C  CB  . GLU   A 1 298 ? 20.15931  20.23305 -44.59550 1.000 78.53150  ? 295 GLU   A CB  1 
ATOM   2311 C  CG  . GLU   A 1 298 ? 20.81461  21.48241 -44.01355 1.000 91.28375  ? 295 GLU   A CG  1 
ATOM   2312 C  CD  . GLU   A 1 298 ? 21.51927  21.22311 -42.69371 1.000 102.80766 ? 295 GLU   A CD  1 
ATOM   2313 O  OE1 . GLU   A 1 298 ? 21.88003  20.05706 -42.43108 1.000 104.94630 ? 295 GLU   A OE1 1 
ATOM   2314 O  OE2 . GLU   A 1 298 ? 21.71181  22.18491 -41.91749 1.000 102.90733 ? 295 GLU   A OE2 1 
ATOM   2315 N  N   . TYR   A 1 299 ? 17.20105  20.45033 -45.36589 1.000 77.52192  ? 296 TYR   A N   1 
ATOM   2316 C  CA  . TYR   A 1 299 ? 16.15374  20.26529 -46.36173 1.000 72.47061  ? 296 TYR   A CA  1 
ATOM   2317 C  C   . TYR   A 1 299 ? 16.11468  21.45454 -47.31036 1.000 73.85137  ? 296 TYR   A C   1 
ATOM   2318 O  O   . TYR   A 1 299 ? 16.00454  22.60290 -46.87066 1.000 75.64438  ? 296 TYR   A O   1 
ATOM   2319 C  CB  . TYR   A 1 299 ? 14.78244  20.07812 -45.70104 1.000 71.82160  ? 296 TYR   A CB  1 
ATOM   2320 C  CG  . TYR   A 1 299 ? 13.66330  19.88102 -46.70019 1.000 69.33512  ? 296 TYR   A CG  1 
ATOM   2321 C  CD1 . TYR   A 1 299 ? 13.01448  20.96952 -47.27611 1.000 71.64649  ? 296 TYR   A CD1 1 
ATOM   2322 C  CD2 . TYR   A 1 299 ? 13.26277  18.60638 -47.07936 1.000 69.01854  ? 296 TYR   A CD2 1 
ATOM   2323 C  CE1 . TYR   A 1 299 ? 12.00189  20.79426 -48.20139 1.000 69.52279  ? 296 TYR   A CE1 1 
ATOM   2324 C  CE2 . TYR   A 1 299 ? 12.24587  18.42142 -48.00244 1.000 76.73702  ? 296 TYR   A CE2 1 
ATOM   2325 C  CZ  . TYR   A 1 299 ? 11.61960  19.52023 -48.55874 1.000 72.20977  ? 296 TYR   A CZ  1 
ATOM   2326 O  OH  . TYR   A 1 299 ? 10.60854  19.34699 -49.47523 1.000 74.59573  ? 296 TYR   A OH  1 
ATOM   2327 N  N   . LYS   A 1 300 ? 16.19669  21.17204 -48.60727 1.000 76.50697  ? 297 LYS   A N   1 
ATOM   2328 C  CA  . LYS   A 1 300 ? 15.89898  22.14431 -49.65092 1.000 76.10325  ? 297 LYS   A CA  1 
ATOM   2329 C  C   . LYS   A 1 300 ? 14.91432  21.51047 -50.62072 1.000 73.31472  ? 297 LYS   A C   1 
ATOM   2330 O  O   . LYS   A 1 300 ? 15.16302  20.40982 -51.12160 1.000 81.03709  ? 297 LYS   A O   1 
ATOM   2331 C  CB  . LYS   A 1 300 ? 17.16341  22.59223 -50.39144 1.000 76.68565  ? 297 LYS   A CB  1 
ATOM   2332 C  CG  . LYS   A 1 300 ? 16.90503  23.66171 -51.43925 1.000 74.70932  ? 297 LYS   A CG  1 
ATOM   2333 C  CD  . LYS   A 1 300 ? 18.11577  23.88246 -52.32965 1.000 91.00938  ? 297 LYS   A CD  1 
ATOM   2334 C  CE  . LYS   A 1 300 ? 17.80163  24.86794 -53.44706 1.000 97.33199  ? 297 LYS   A CE  1 
ATOM   2335 N  NZ  . LYS   A 1 300 ? 18.92566  24.98745 -54.41704 1.000 95.41241  ? 297 LYS   A NZ  1 
ATOM   2336 N  N   . GLY   A 1 301 ? 13.79727  22.18901 -50.87534 1.000 68.05551  ? 298 GLY   A N   1 
ATOM   2337 C  CA  . GLY   A 1 301 ? 12.78141  21.65012 -51.75026 1.000 65.11351  ? 298 GLY   A CA  1 
ATOM   2338 C  C   . GLY   A 1 301 ? 11.68026  22.63911 -52.07385 1.000 66.70217  ? 298 GLY   A C   1 
ATOM   2339 O  O   . GLY   A 1 301 ? 11.69993  23.79278 -51.63340 1.000 72.12863  ? 298 GLY   A O   1 
ATOM   2340 N  N   . PRO   A 1 302 ? 10.68824  22.19967 -52.86249 1.000 62.72755  ? 299 PRO   A N   1 
ATOM   2341 C  CA  . PRO   A 1 302 ? 9.59111   23.08883 -53.27362 1.000 62.75536  ? 299 PRO   A CA  1 
ATOM   2342 C  C   . PRO   A 1 302 ? 8.56206   23.24353 -52.16393 1.000 65.63201  ? 299 PRO   A C   1 
ATOM   2343 O  O   . PRO   A 1 302 ? 7.75767   22.34251 -51.90815 1.000 60.59722  ? 299 PRO   A O   1 
ATOM   2344 C  CB  . PRO   A 1 302 ? 9.00936   22.37190 -54.50004 1.000 54.05535  ? 299 PRO   A CB  1 
ATOM   2345 C  CG  . PRO   A 1 302 ? 9.28841   20.92477 -54.24602 1.000 54.93925  ? 299 PRO   A CG  1 
ATOM   2346 C  CD  . PRO   A 1 302 ? 10.58782  20.86504 -53.48064 1.000 61.30309  ? 299 PRO   A CD  1 
ATOM   2347 N  N   . ILE   A 1 303 ? 8.57259   24.40277 -51.51321 1.000 66.49495  ? 300 ILE   A N   1 
ATOM   2348 C  CA  . ILE   A 1 303 ? 7.73580   24.67343 -50.35114 1.000 58.46155  ? 300 ILE   A CA  1 
ATOM   2349 C  C   . ILE   A 1 303 ? 6.70356   25.72897 -50.72144 1.000 60.26399  ? 300 ILE   A C   1 
ATOM   2350 O  O   . ILE   A 1 303 ? 7.01347   26.69087 -51.43502 1.000 64.89973  ? 300 ILE   A O   1 
ATOM   2351 C  CB  . ILE   A 1 303 ? 8.59408   25.12897 -49.15464 1.000 58.43698  ? 300 ILE   A CB  1 
ATOM   2352 C  CG1 . ILE   A 1 303 ? 9.62016   24.05202 -48.80071 1.000 58.69651  ? 300 ILE   A CG1 1 
ATOM   2353 C  CG2 . ILE   A 1 303 ? 7.72453   25.44350 -47.95081 1.000 55.03205  ? 300 ILE   A CG2 1 
ATOM   2354 C  CD1 . ILE   A 1 303 ? 9.00335   22.71363 -48.46555 1.000 61.04133  ? 300 ILE   A CD1 1 
ATOM   2355 N  N   . THR   A 1 304 ? 5.47298   25.54697 -50.23857 1.000 57.28445  ? 301 THR   A N   1 
ATOM   2356 C  CA  . THR   A 1 304 ? 4.38519   26.47737 -50.51337 1.000 61.64137  ? 301 THR   A CA  1 
ATOM   2357 C  C   . THR   A 1 304 ? 3.77105   27.09757 -49.26384 1.000 58.99561  ? 301 THR   A C   1 
ATOM   2358 O  O   . THR   A 1 304 ? 3.24882   28.21070 -49.34728 1.000 58.22706  ? 301 THR   A O   1 
ATOM   2359 C  CB  . THR   A 1 304 ? 3.27671   25.78320 -51.32868 1.000 59.30710  ? 301 THR   A CB  1 
ATOM   2360 O  OG1 . THR   A 1 304 ? 2.16431   26.67244 -51.49622 1.000 60.54076  ? 301 THR   A OG1 1 
ATOM   2361 C  CG2 . THR   A 1 304 ? 2.80739   24.51829 -50.62356 1.000 63.37686  ? 301 THR   A CG2 1 
ATOM   2362 N  N   . ASP   A 1 305 ? 3.81628   26.41901 -48.11545 1.000 57.51769  ? 302 ASP   A N   1 
ATOM   2363 C  CA  . ASP   A 1 305 ? 3.35273   26.97611 -46.84922 1.000 60.69337  ? 302 ASP   A CA  1 
ATOM   2364 C  C   . ASP   A 1 305 ? 4.40618   26.73873 -45.77996 1.000 56.45095  ? 302 ASP   A C   1 
ATOM   2365 O  O   . ASP   A 1 305 ? 5.03979   25.68054 -45.75471 1.000 55.30574  ? 302 ASP   A O   1 
ATOM   2366 C  CB  . ASP   A 1 305 ? 2.02687   26.35187 -46.38275 1.000 62.48834  ? 302 ASP   A CB  1 
ATOM   2367 C  CG  . ASP   A 1 305 ? 1.00505   26.23073 -47.49502 1.000 68.30841  ? 302 ASP   A CG  1 
ATOM   2368 O  OD1 . ASP   A 1 305 ? 0.76057   27.23097 -48.20414 1.000 68.22197  ? 302 ASP   A OD1 1 
ATOM   2369 O  OD2 . ASP   A 1 305 ? 0.44298   25.12490 -47.65371 1.000 67.35573  ? 302 ASP   A OD2 1 
ATOM   2370 N  N   . VAL   A 1 306 ? 4.59649   27.72444 -44.90261 1.000 56.86369  ? 303 VAL   A N   1 
ATOM   2371 C  CA  . VAL   A 1 306 ? 5.46399   27.58220 -43.73426 1.000 58.62002  ? 303 VAL   A CA  1 
ATOM   2372 C  C   . VAL   A 1 306 ? 4.75438   28.18869 -42.53103 1.000 53.80743  ? 303 VAL   A C   1 
ATOM   2373 O  O   . VAL   A 1 306 ? 4.21835   29.29892 -42.61415 1.000 52.79494  ? 303 VAL   A O   1 
ATOM   2374 C  CB  . VAL   A 1 306 ? 6.84063   28.24974 -43.92694 1.000 56.78470  ? 303 VAL   A CB  1 
ATOM   2375 C  CG1 . VAL   A 1 306 ? 7.71250   27.99742 -42.71023 1.000 55.64670  ? 303 VAL   A CG1 1 
ATOM   2376 C  CG2 . VAL   A 1 306 ? 7.52903   27.72858 -45.17062 1.000 54.44287  ? 303 VAL   A CG2 1 
ATOM   2377 N  N   . PHE   A 1 307 ? 4.74150   27.46110 -41.41878 1.000 57.89435  ? 304 PHE   A N   1 
ATOM   2378 C  CA  . PHE   A 1 307 ? 4.08781   27.90277 -40.19337 1.000 57.61869  ? 304 PHE   A CA  1 
ATOM   2379 C  C   . PHE   A 1 307 ? 5.13196   28.27047 -39.14911 1.000 53.38329  ? 304 PHE   A C   1 
ATOM   2380 O  O   . PHE   A 1 307 ? 6.08486   27.51835 -38.92230 1.000 53.62527  ? 304 PHE   A O   1 
ATOM   2381 C  CB  . PHE   A 1 307 ? 3.15290   26.82020 -39.65183 1.000 53.24605  ? 304 PHE   A CB  1 
ATOM   2382 C  CG  . PHE   A 1 307 ? 1.98896   26.52397 -40.55203 1.000 60.29242  ? 304 PHE   A CG  1 
ATOM   2383 C  CD1 . PHE   A 1 307 ? 2.13334   25.68078 -41.64346 1.000 57.75735  ? 304 PHE   A CD1 1 
ATOM   2384 C  CD2 . PHE   A 1 307 ? 0.74949   27.08941 -40.30700 1.000 53.43417  ? 304 PHE   A CD2 1 
ATOM   2385 C  CE1 . PHE   A 1 307 ? 1.06334   25.40944 -42.47558 1.000 54.06726  ? 304 PHE   A CE1 1 
ATOM   2386 C  CE2 . PHE   A 1 307 ? -0.32270  26.82016 -41.13238 1.000 59.41954  ? 304 PHE   A CE2 1 
ATOM   2387 C  CZ  . PHE   A 1 307 ? -0.16549  25.97953 -42.21956 1.000 55.91896  ? 304 PHE   A CZ  1 
ATOM   2388 N  N   . TYR   A 1 308 ? 4.93582   29.41370 -38.50453 1.000 58.66104  ? 305 TYR   A N   1 
ATOM   2389 C  CA  . TYR   A 1 308 ? 5.83961   29.90875 -37.48085 1.000 55.66653  ? 305 TYR   A CA  1 
ATOM   2390 C  C   . TYR   A 1 308 ? 5.08118   30.11189 -36.17846 1.000 61.28578  ? 305 TYR   A C   1 
ATOM   2391 O  O   . TYR   A 1 308 ? 3.89868   30.46418 -36.18046 1.000 59.89806  ? 305 TYR   A O   1 
ATOM   2392 C  CB  . TYR   A 1 308 ? 6.48904   31.23047 -37.89842 1.000 54.81026  ? 305 TYR   A CB  1 
ATOM   2393 C  CG  . TYR   A 1 308 ? 7.26122   31.16784 -39.19246 1.000 56.72307  ? 305 TYR   A CG  1 
ATOM   2394 C  CD1 . TYR   A 1 308 ? 6.64787   31.45084 -40.40563 1.000 60.06152  ? 305 TYR   A CD1 1 
ATOM   2395 C  CD2 . TYR   A 1 308 ? 8.60613   30.83045 -39.20127 1.000 51.00839  ? 305 TYR   A CD2 1 
ATOM   2396 C  CE1 . TYR   A 1 308 ? 7.35423   31.39853 -41.59312 1.000 57.82968  ? 305 TYR   A CE1 1 
ATOM   2397 C  CE2 . TYR   A 1 308 ? 9.32139   30.77639 -40.38234 1.000 63.65923  ? 305 TYR   A CE2 1 
ATOM   2398 C  CZ  . TYR   A 1 308 ? 8.69100   31.06223 -41.57602 1.000 61.60352  ? 305 TYR   A CZ  1 
ATOM   2399 O  OH  . TYR   A 1 308 ? 9.39679   31.00887 -42.75808 1.000 57.65422  ? 305 TYR   A OH  1 
ATOM   2400 N  N   . LYS   A 1 309 ? 5.76843   29.88339 -35.06340 1.000 65.14468  ? 306 LYS   A N   1 
ATOM   2401 C  CA  . LYS   A 1 309 ? 5.18996   30.18733 -33.76490 1.000 56.58165  ? 306 LYS   A CA  1 
ATOM   2402 C  C   . LYS   A 1 309 ? 5.33095   31.67295 -33.47148 1.000 59.72456  ? 306 LYS   A C   1 
ATOM   2403 O  O   . LYS   A 1 309 ? 6.28548   32.32695 -33.90233 1.000 66.79507  ? 306 LYS   A O   1 
ATOM   2404 C  CB  . LYS   A 1 309 ? 5.86649   29.37920 -32.65912 1.000 53.76689  ? 306 LYS   A CB  1 
ATOM   2405 C  CG  . LYS   A 1 309 ? 5.32396   27.97044 -32.50602 1.000 68.78484  ? 306 LYS   A CG  1 
ATOM   2406 C  CD  . LYS   A 1 309 ? 5.96370   27.24674 -31.33437 1.000 72.16489  ? 306 LYS   A CD  1 
ATOM   2407 C  CE  . LYS   A 1 309 ? 5.42969   25.82679 -31.20244 1.000 82.09903  ? 306 LYS   A CE  1 
ATOM   2408 N  NZ  . LYS   A 1 309 ? 4.02470   25.70410 -31.68695 1.000 74.54630  ? 306 LYS   A NZ  1 
ATOM   2409 N  N   . GLU   A 1 310 ? 4.35149   32.21104 -32.75130 1.000 63.47802  ? 307 GLU   A N   1 
ATOM   2410 C  CA  . GLU   A 1 310 ? 4.31764   33.63737 -32.47244 1.000 69.08728  ? 307 GLU   A CA  1 
ATOM   2411 C  C   . GLU   A 1 310 ? 3.56221   33.86243 -31.16865 1.000 69.61902  ? 307 GLU   A C   1 
ATOM   2412 O  O   . GLU   A 1 310 ? 2.84377   32.98556 -30.68157 1.000 69.98913  ? 307 GLU   A O   1 
ATOM   2413 C  CB  . GLU   A 1 310 ? 3.67443   34.40135 -33.64503 1.000 62.46120  ? 307 GLU   A CB  1 
ATOM   2414 C  CG  . GLU   A 1 310 ? 3.63587   35.92353 -33.51773 1.000 76.09228  ? 307 GLU   A CG  1 
ATOM   2415 C  CD  . GLU   A 1 310 ? 5.00905   36.53544 -33.31593 1.000 82.21914  ? 307 GLU   A CD  1 
ATOM   2416 O  OE1 . GLU   A 1 310 ? 5.70968   36.77249 -34.32281 1.000 83.97832  ? 307 GLU   A OE1 1 
ATOM   2417 O  OE2 . GLU   A 1 310 ? 5.38894   36.77469 -32.14874 1.000 82.84078  ? 307 GLU   A OE2 1 
ATOM   2418 N  N   . ASN   A 1 311 ? 3.73657   35.05328 -30.60512 1.000 68.33954  ? 308 ASN   A N   1 
ATOM   2419 C  CA  . ASN   A 1 311 ? 2.96931   35.47214 -29.44276 1.000 71.97779  ? 308 ASN   A CA  1 
ATOM   2420 C  C   . ASN   A 1 311 ? 2.64383   36.94985 -29.59356 1.000 76.04562  ? 308 ASN   A C   1 
ATOM   2421 O  O   . ASN   A 1 311 ? 1.48841   37.32503 -29.81450 1.000 77.24287  ? 308 ASN   A O   1 
ATOM   2422 C  CB  . ASN   A 1 311 ? 3.73995   35.19824 -28.14934 1.000 68.68301  ? 308 ASN   A CB  1 
ATOM   2423 C  CG  . ASN   A 1 311 ? 3.01468   35.70980 -26.91723 1.000 91.45147  ? 308 ASN   A CG  1 
ATOM   2424 O  OD1 . ASN   A 1 311 ? 1.95449   35.20168 -26.54979 1.000 101.69387 ? 308 ASN   A OD1 1 
ATOM   2425 N  ND2 . ASN   A 1 311 ? 3.59214   36.71263 -26.26343 1.000 103.34384 ? 308 ASN   A ND2 1 
ATOM   2426 N  N   . SER   A 1 312 ? 3.66721   37.78982 -29.48287 1.000 77.03050  ? 309 SER   A N   1 
ATOM   2427 C  CA  . SER   A 1 312 ? 3.52642   39.22801 -29.64950 1.000 78.36091  ? 309 SER   A CA  1 
ATOM   2428 C  C   . SER   A 1 312 ? 4.80332   39.74892 -30.28493 1.000 79.72299  ? 309 SER   A C   1 
ATOM   2429 O  O   . SER   A 1 312 ? 5.89788   39.45751 -29.79718 1.000 82.70608  ? 309 SER   A O   1 
ATOM   2430 C  CB  . SER   A 1 312 ? 3.26369   39.92759 -28.31321 1.000 74.52319  ? 309 SER   A CB  1 
ATOM   2431 O  OG  . SER   A 1 312 ? 3.06702   41.31544 -28.50767 1.000 88.70266  ? 309 SER   A OG  1 
ATOM   2432 N  N   . TYR   A 1 313 ? 4.66299   40.48428 -31.38254 1.000 78.83947  ? 310 TYR   A N   1 
ATOM   2433 C  CA  . TYR   A 1 313 ? 5.80538   41.05106 -32.07924 1.000 73.69799  ? 310 TYR   A CA  1 
ATOM   2434 C  C   . TYR   A 1 313 ? 5.54715   42.52615 -32.33939 1.000 82.14372  ? 310 TYR   A C   1 
ATOM   2435 O  O   . TYR   A 1 313 ? 4.42675   42.92033 -32.67946 1.000 84.15072  ? 310 TYR   A O   1 
ATOM   2436 C  CB  . TYR   A 1 313 ? 6.07233   40.32295 -33.40508 1.000 73.28895  ? 310 TYR   A CB  1 
ATOM   2437 C  CG  . TYR   A 1 313 ? 7.04022   41.03605 -34.32344 1.000 75.13952  ? 310 TYR   A CG  1 
ATOM   2438 C  CD1 . TYR   A 1 313 ? 8.41171   40.88349 -34.15644 1.000 73.37916  ? 310 TYR   A CD1 1 
ATOM   2439 C  CD2 . TYR   A 1 313 ? 6.59364   41.86508 -35.34418 1.000 75.67713  ? 310 TYR   A CD2 1 
ATOM   2440 C  CE1 . TYR   A 1 313 ? 9.31051   41.52667 -34.98278 1.000 72.93280  ? 310 TYR   A CE1 1 
ATOM   2441 C  CE2 . TYR   A 1 313 ? 7.48876   42.51793 -36.17649 1.000 79.96701  ? 310 TYR   A CE2 1 
ATOM   2442 C  CZ  . TYR   A 1 313 ? 8.84541   42.34358 -35.99043 1.000 77.46252  ? 310 TYR   A CZ  1 
ATOM   2443 O  OH  . TYR   A 1 313 ? 9.73924   42.98841 -36.81477 1.000 74.74016  ? 310 TYR   A OH  1 
ATOM   2444 N  N   . THR   A 1 314 ? 6.58725   43.33747 -32.17024 1.000 86.10242  ? 311 THR   A N   1 
ATOM   2445 C  CA  . THR   A 1 314 ? 6.54473   44.75084 -32.51248 1.000 82.25001  ? 311 THR   A CA  1 
ATOM   2446 C  C   . THR   A 1 314 ? 7.84260   45.07885 -33.23082 1.000 86.81505  ? 311 THR   A C   1 
ATOM   2447 O  O   . THR   A 1 314 ? 8.89936   44.54115 -32.88705 1.000 85.90736  ? 311 THR   A O   1 
ATOM   2448 C  CB  . THR   A 1 314 ? 6.37097   45.63903 -31.27827 1.000 81.41309  ? 311 THR   A CB  1 
ATOM   2449 O  OG1 . THR   A 1 314 ? 5.26202   45.16812 -30.50113 1.000 84.69215  ? 311 THR   A OG1 1 
ATOM   2450 C  CG2 . THR   A 1 314 ? 6.10647   47.07743 -31.69801 1.000 77.74015  ? 311 THR   A CG2 1 
ATOM   2451 N  N   . THR   A 1 315 ? 7.76316   45.96486 -34.21786 1.000 91.13990  ? 312 THR   A N   1 
ATOM   2452 C  CA  . THR   A 1 315 ? 8.89851   46.23575 -35.08422 1.000 90.28723  ? 312 THR   A CA  1 
ATOM   2453 C  C   . THR   A 1 315 ? 9.79878   47.32072 -34.50014 1.000 95.36273  ? 312 THR   A C   1 
ATOM   2454 O  O   . THR   A 1 315 ? 9.38308   48.14591 -33.68121 1.000 94.19872  ? 312 THR   A O   1 
ATOM   2455 C  CB  . THR   A 1 315 ? 8.42169   46.65203 -36.48055 1.000 88.82153  ? 312 THR   A CB  1 
ATOM   2456 O  OG1 . THR   A 1 315 ? 9.53738   46.71195 -37.37817 1.000 91.14891  ? 312 THR   A OG1 1 
ATOM   2457 C  CG2 . THR   A 1 315 ? 7.73871   48.01270 -36.43639 1.000 83.01996  ? 312 THR   A CG2 1 
ATOM   2458 N  N   . THR   A 1 316 ? 11.06333  47.28511 -34.92255 1.000 104.55623 ? 313 THR   A N   1 
ATOM   2459 C  CA  . THR   A 1 316 ? 12.05101  48.29620 -34.57554 1.000 107.95021 ? 313 THR   A CA  1 
ATOM   2460 C  C   . THR   A 1 316 ? 12.25471  49.32313 -35.68252 1.000 108.78959 ? 313 THR   A C   1 
ATOM   2461 O  O   . THR   A 1 316 ? 12.90741  50.34591 -35.44595 1.000 118.01998 ? 313 THR   A O   1 
ATOM   2462 C  CB  . THR   A 1 316 ? 13.39684  47.63537 -34.24220 1.000 97.78799  ? 313 THR   A CB  1 
ATOM   2463 O  OG1 . THR   A 1 316 ? 13.88487  46.93166 -35.39146 1.000 111.82984 ? 313 THR   A OG1 1 
ATOM   2464 C  CG2 . THR   A 1 316 ? 13.23827  46.65665 -33.08589 1.000 85.75077  ? 313 THR   A CG2 1 
ATOM   2465 N  N   . ILE   A 1 317 ? 11.71835  49.07546 -36.87661 1.000 101.08722 ? 314 ILE   A N   1 
ATOM   2466 C  CA  . ILE   A 1 317 ? 11.80549  50.03854 -37.96797 1.000 108.51077 ? 314 ILE   A CA  1 
ATOM   2467 C  C   . ILE   A 1 317 ? 11.01501  51.28491 -37.59029 1.000 113.21996 ? 314 ILE   A C   1 
ATOM   2468 O  O   . ILE   A 1 317 ? 9.81855   51.21114 -37.28481 1.000 108.43425 ? 314 ILE   A O   1 
ATOM   2469 C  CB  . ILE   A 1 317 ? 11.29223  49.42720 -39.27789 1.000 107.47411 ? 314 ILE   A CB  1 
ATOM   2470 C  CG1 . ILE   A 1 317 ? 12.22907  48.31262 -39.74993 1.000 102.19173 ? 314 ILE   A CG1 1 
ATOM   2471 C  CG2 . ILE   A 1 317 ? 11.13372  50.49885 -40.34932 1.000 108.25055 ? 314 ILE   A CG2 1 
ATOM   2472 C  CD1 . ILE   A 1 317 ? 11.77500  47.63472 -41.02316 1.000 100.96313 ? 314 ILE   A CD1 1 
ATOM   2473 N  N   . LYS   A 1 318 ? 11.68288  52.43445 -37.60484 1.000 117.02010 ? 315 LYS   A N   1 
ATOM   2474 C  CA  . LYS   A 1 318 ? 11.04041  53.69820 -37.26131 1.000 116.67532 ? 315 LYS   A CA  1 
ATOM   2475 C  C   . LYS   A 1 318 ? 10.20984  54.22946 -38.42850 1.000 121.38707 ? 315 LYS   A C   1 
ATOM   2476 O  O   . LYS   A 1 318 ? 9.06288   53.82657 -38.62886 1.000 125.36342 ? 315 LYS   A O   1 
ATOM   2477 C  CB  . LYS   A 1 318 ? 12.08774  54.73226 -36.84172 1.000 111.20617 ? 315 LYS   A CB  1 
ATOM   2478 O  OXT . LYS   A 1 318 ? 10.66255  55.07209 -39.20342 1.000 119.38905 ? 315 LYS   A OXT 1 
ATOM   2479 N  N   . THR   B 1 7   ? 43.46118  -3.45404 -29.43671 1.000 133.24879 ? 4   THR   B N   1 
ATOM   2480 C  CA  . THR   B 1 7   ? 43.09146  -2.05669 -29.62200 1.000 131.39199 ? 4   THR   B CA  1 
ATOM   2481 C  C   . THR   B 1 7   ? 41.80942  -1.94869 -30.44166 1.000 132.50302 ? 4   THR   B C   1 
ATOM   2482 O  O   . THR   B 1 7   ? 41.69056  -2.56386 -31.50105 1.000 126.03882 ? 4   THR   B O   1 
ATOM   2483 C  CB  . THR   B 1 7   ? 44.21792  -1.27366 -30.31821 1.000 125.26005 ? 4   THR   B CB  1 
ATOM   2484 O  OG1 . THR   B 1 7   ? 45.43049  -1.41884 -29.56830 1.000 128.16079 ? 4   THR   B OG1 1 
ATOM   2485 C  CG2 . THR   B 1 7   ? 43.86434  0.20240  -30.42884 1.000 119.65638 ? 4   THR   B CG2 1 
ATOM   2486 N  N   . ILE   B 1 8   ? 40.85547  -1.15848 -29.94939 1.000 137.92238 ? 5   ILE   B N   1 
ATOM   2487 C  CA  . ILE   B 1 8   ? 39.60366  -0.89878 -30.64658 1.000 130.44341 ? 5   ILE   B CA  1 
ATOM   2488 C  C   . ILE   B 1 8   ? 39.46325  0.60015  -30.89724 1.000 133.27056 ? 5   ILE   B C   1 
ATOM   2489 O  O   . ILE   B 1 8   ? 40.18133  1.42373  -30.32924 1.000 131.69290 ? 5   ILE   B O   1 
ATOM   2490 C  CB  . ILE   B 1 8   ? 38.38285  -1.43497 -29.87310 1.000 112.86017 ? 5   ILE   B CB  1 
ATOM   2491 N  N   . LYS   B 1 9   ? 38.51829  0.93933  -31.76948 1.000 130.63555 ? 6   LYS   B N   1 
ATOM   2492 C  CA  . LYS   B 1 9   ? 38.18737  2.31885  -32.09912 1.000 128.04030 ? 6   LYS   B CA  1 
ATOM   2493 C  C   . LYS   B 1 9   ? 36.79186  2.62360  -31.57465 1.000 126.57909 ? 6   LYS   B C   1 
ATOM   2494 O  O   . LYS   B 1 9   ? 35.85553  1.85224  -31.80908 1.000 126.36972 ? 6   LYS   B O   1 
ATOM   2495 C  CB  . LYS   B 1 9   ? 38.23869  2.55878  -33.60997 1.000 123.46869 ? 6   LYS   B CB  1 
ATOM   2496 C  CG  . LYS   B 1 9   ? 37.67508  3.90850  -34.03156 1.000 121.51980 ? 6   LYS   B CG  1 
ATOM   2497 C  CD  . LYS   B 1 9   ? 37.43291  3.97297  -35.53096 1.000 127.87481 ? 6   LYS   B CD  1 
ATOM   2498 C  CE  . LYS   B 1 9   ? 36.71136  5.25604  -35.91487 1.000 116.26208 ? 6   LYS   B CE  1 
ATOM   2499 N  NZ  . LYS   B 1 9   ? 36.36688  5.28605  -37.36210 1.000 114.88110 ? 6   LYS   B NZ  1 
ATOM   2500 N  N   . VAL   B 1 10  ? 36.65310  3.74395  -30.86681 1.000 120.71299 ? 7   VAL   B N   1 
ATOM   2501 C  CA  . VAL   B 1 10  ? 35.38572  4.14151  -30.26973 1.000 111.11641 ? 7   VAL   B CA  1 
ATOM   2502 C  C   . VAL   B 1 10  ? 35.17671  5.62951  -30.51343 1.000 112.35944 ? 7   VAL   B C   1 
ATOM   2503 O  O   . VAL   B 1 10  ? 36.05578  6.33565  -31.01156 1.000 115.20187 ? 7   VAL   B O   1 
ATOM   2504 C  CB  . VAL   B 1 10  ? 35.32283  3.83955  -28.75669 1.000 111.70232 ? 7   VAL   B CB  1 
ATOM   2505 C  CG1 . VAL   B 1 10  ? 35.35217  2.34101  -28.50405 1.000 112.21634 ? 7   VAL   B CG1 1 
ATOM   2506 C  CG2 . VAL   B 1 10  ? 36.46362  4.53455  -28.03029 1.000 115.76310 ? 7   VAL   B CG2 1 
ATOM   2507 N  N   . PHE   B 1 11  ? 33.98540  6.09751  -30.15572 1.000 114.54846 ? 8   PHE   B N   1 
ATOM   2508 C  CA  . PHE   B 1 11  ? 33.64201  7.51074  -30.18382 1.000 106.38496 ? 8   PHE   B CA  1 
ATOM   2509 C  C   . PHE   B 1 11  ? 33.35161  7.96553  -28.76163 1.000 102.50761 ? 8   PHE   B C   1 
ATOM   2510 O  O   . PHE   B 1 11  ? 32.63872  7.27763  -28.02213 1.000 97.34808  ? 8   PHE   B O   1 
ATOM   2511 C  CB  . PHE   B 1 11  ? 32.43160  7.76579  -31.08369 1.000 104.18997 ? 8   PHE   B CB  1 
ATOM   2512 C  CG  . PHE   B 1 11  ? 32.69445  7.51568  -32.54012 1.000 107.36404 ? 8   PHE   B CG  1 
ATOM   2513 C  CD1 . PHE   B 1 11  ? 33.29242  8.48362  -33.32874 1.000 106.16074 ? 8   PHE   B CD1 1 
ATOM   2514 C  CD2 . PHE   B 1 11  ? 32.34200  6.30824  -33.12125 1.000 112.32005 ? 8   PHE   B CD2 1 
ATOM   2515 C  CE1 . PHE   B 1 11  ? 33.52952  8.25383  -34.67159 1.000 108.47914 ? 8   PHE   B CE1 1 
ATOM   2516 C  CE2 . PHE   B 1 11  ? 32.57978  6.07230  -34.46246 1.000 114.61394 ? 8   PHE   B CE2 1 
ATOM   2517 C  CZ  . PHE   B 1 11  ? 33.17518  7.04656  -35.23794 1.000 111.46388 ? 8   PHE   B CZ  1 
ATOM   2518 N  N   . THR   B 1 12  ? 33.90295  9.11306  -28.37931 1.000 97.18132  ? 9   THR   B N   1 
ATOM   2519 C  CA  . THR   B 1 12  ? 33.56510  9.75005  -27.11633 1.000 95.63293  ? 9   THR   B CA  1 
ATOM   2520 C  C   . THR   B 1 12  ? 32.78806  11.03142 -27.38106 1.000 84.12768  ? 9   THR   B C   1 
ATOM   2521 O  O   . THR   B 1 12  ? 33.02351  11.73075 -28.37065 1.000 81.11569  ? 9   THR   B O   1 
ATOM   2522 C  CB  . THR   B 1 12  ? 34.81208  10.06626 -26.28144 1.000 90.18906  ? 9   THR   B CB  1 
ATOM   2523 O  OG1 . THR   B 1 12  ? 35.71324  10.88014 -27.04330 1.000 100.65321 ? 9   THR   B OG1 1 
ATOM   2524 C  CG2 . THR   B 1 12  ? 35.51079  8.78589  -25.86062 1.000 91.41189  ? 9   THR   B CG2 1 
ATOM   2525 N  N   . THR   B 1 13  ? 31.85311  11.32813 -26.48486 1.000 75.85495  ? 10  THR   B N   1 
ATOM   2526 C  CA  . THR   B 1 13  ? 30.99964  12.49271 -26.64731 1.000 75.33399  ? 10  THR   B CA  1 
ATOM   2527 C  C   . THR   B 1 13  ? 30.48514  12.91931 -25.28399 1.000 75.00603  ? 10  THR   B C   1 
ATOM   2528 O  O   . THR   B 1 13  ? 30.55579  12.17162 -24.30538 1.000 76.89242  ? 10  THR   B O   1 
ATOM   2529 C  CB  . THR   B 1 13  ? 29.82704  12.20413 -27.59278 1.000 80.19704  ? 10  THR   B CB  1 
ATOM   2530 O  OG1 . THR   B 1 13  ? 29.13717  13.42288 -27.89523 1.000 79.84240  ? 10  THR   B OG1 1 
ATOM   2531 C  CG2 . THR   B 1 13  ? 28.85343  11.22438 -26.94958 1.000 79.08721  ? 10  THR   B CG2 1 
ATOM   2532 N  N   . VAL   B 1 14  ? 29.97509  14.14405 -25.23770 1.000 75.58250  ? 11  VAL   B N   1 
ATOM   2533 C  CA  . VAL   B 1 14  ? 29.23413  14.62203 -24.08105 1.000 77.81393  ? 11  VAL   B CA  1 
ATOM   2534 C  C   . VAL   B 1 14  ? 27.80281  15.00882 -24.42758 1.000 76.82047  ? 11  VAL   B C   1 
ATOM   2535 O  O   . VAL   B 1 14  ? 26.95710  15.07921 -23.52049 1.000 72.04021  ? 11  VAL   B O   1 
ATOM   2536 C  CB  . VAL   B 1 14  ? 29.96728  15.80290 -23.40700 1.000 72.15070  ? 11  VAL   B CB  1 
ATOM   2537 C  CG1 . VAL   B 1 14  ? 29.77943  17.08870 -24.20427 1.000 68.53501  ? 11  VAL   B CG1 1 
ATOM   2538 C  CG2 . VAL   B 1 14  ? 29.52028  15.96452 -21.96291 1.000 78.41024  ? 11  VAL   B CG2 1 
ATOM   2539 N  N   . ASP   B 1 15  ? 27.48660  15.22479 -25.70519 1.000 72.59781  ? 12  ASP   B N   1 
ATOM   2540 C  CA  . ASP   B 1 15  ? 26.15709  15.62398 -26.13575 1.000 70.32701  ? 12  ASP   B CA  1 
ATOM   2541 C  C   . ASP   B 1 15  ? 25.53531  14.65602 -27.13039 1.000 76.57080  ? 12  ASP   B C   1 
ATOM   2542 O  O   . ASP   B 1 15  ? 24.38689  14.86734 -27.53868 1.000 78.75799  ? 12  ASP   B O   1 
ATOM   2543 C  CB  . ASP   B 1 15  ? 26.20427  17.02600 -26.75932 1.000 69.03644  ? 12  ASP   B CB  1 
ATOM   2544 C  CG  . ASP   B 1 15  ? 27.26439  17.15172 -27.84845 1.000 77.23277  ? 12  ASP   B CG  1 
ATOM   2545 O  OD1 . ASP   B 1 15  ? 27.67645  16.12089 -28.42489 1.000 77.22445  ? 12  ASP   B OD1 1 
ATOM   2546 O  OD2 . ASP   B 1 15  ? 27.69024  18.29109 -28.12901 1.000 77.34240  ? 12  ASP   B OD2 1 
ATOM   2547 N  N   . ASN   B 1 16  ? 26.26228  13.61187 -27.53489 1.000 79.89365  ? 13  ASN   B N   1 
ATOM   2548 C  CA  . ASN   B 1 16  ? 25.82689  12.66991 -28.56959 1.000 86.08513  ? 13  ASN   B CA  1 
ATOM   2549 C  C   . ASN   B 1 16  ? 25.56762  13.37533 -29.89957 1.000 83.49849  ? 13  ASN   B C   1 
ATOM   2550 O  O   . ASN   B 1 16  ? 24.78936  12.90082 -30.73023 1.000 85.04639  ? 13  ASN   B O   1 
ATOM   2551 C  CB  . ASN   B 1 16  ? 24.59189  11.87839 -28.12642 1.000 93.39946  ? 13  ASN   B CB  1 
ATOM   2552 C  CG  . ASN   B 1 16  ? 24.40098  10.59779 -28.91826 1.000 88.32635  ? 13  ASN   B CG  1 
ATOM   2553 O  OD1 . ASN   B 1 16  ? 25.29250  10.16716 -29.65040 1.000 86.27888  ? 13  ASN   B OD1 1 
ATOM   2554 N  ND2 . ASN   B 1 16  ? 23.23380  9.98204  -28.77305 1.000 91.65950  ? 13  ASN   B ND2 1 
ATOM   2555 N  N   . ILE   B 1 17  ? 26.21907  14.51690 -30.10713 1.000 81.00975  ? 14  ILE   B N   1 
ATOM   2556 C  CA  . ILE   B 1 17  ? 26.10749  15.26541 -31.35314 1.000 80.62122  ? 14  ILE   B CA  1 
ATOM   2557 C  C   . ILE   B 1 17  ? 27.50558  15.46169 -31.92102 1.000 81.65554  ? 14  ILE   B C   1 
ATOM   2558 O  O   . ILE   B 1 17  ? 27.78746  15.07210 -33.05968 1.000 87.60453  ? 14  ILE   B O   1 
ATOM   2559 C  CB  . ILE   B 1 17  ? 25.38868  16.61053 -31.14203 1.000 80.41726  ? 14  ILE   B CB  1 
ATOM   2560 C  CG1 . ILE   B 1 17  ? 23.89433  16.38031 -30.90083 1.000 72.38136  ? 14  ILE   B CG1 1 
ATOM   2561 C  CG2 . ILE   B 1 17  ? 25.61319  17.53370 -32.32825 1.000 66.15643  ? 14  ILE   B CG2 1 
ATOM   2562 C  CD1 . ILE   B 1 17  ? 23.12069  17.64713 -30.62038 1.000 73.95409  ? 14  ILE   B CD1 1 
ATOM   2563 N  N   . ASN   B 1 18  ? 28.39095  16.06236 -31.12909 1.000 83.50613  ? 15  ASN   B N   1 
ATOM   2564 C  CA  . ASN   B 1 18  ? 29.79898  16.19399 -31.49465 1.000 78.82845  ? 15  ASN   B CA  1 
ATOM   2565 C  C   . ASN   B 1 18  ? 30.52078  14.93957 -31.02225 1.000 83.91702  ? 15  ASN   B C   1 
ATOM   2566 O  O   . ASN   B 1 18  ? 30.79328  14.77616 -29.83088 1.000 83.23887  ? 15  ASN   B O   1 
ATOM   2567 C  CB  . ASN   B 1 18  ? 30.40630  17.44978 -30.88123 1.000 80.62536  ? 15  ASN   B CB  1 
ATOM   2568 C  CG  . ASN   B 1 18  ? 29.70021  18.71252 -31.32144 1.000 86.89098  ? 15  ASN   B CG  1 
ATOM   2569 O  OD1 . ASN   B 1 18  ? 30.12371  19.37559 -32.26833 1.000 95.72342  ? 15  ASN   B OD1 1 
ATOM   2570 N  ND2 . ASN   B 1 18  ? 28.61405  19.05250 -30.63689 1.000 80.17628  ? 15  ASN   B ND2 1 
ATOM   2571 N  N   . LEU   B 1 19  ? 30.81982  14.04352 -31.95743 1.000 89.23783  ? 16  LEU   B N   1 
ATOM   2572 C  CA  . LEU   B 1 19  ? 31.54918  12.82485 -31.64509 1.000 87.67358  ? 16  LEU   B CA  1 
ATOM   2573 C  C   . LEU   B 1 19  ? 33.03396  13.03450 -31.90206 1.000 87.23865  ? 16  LEU   B C   1 
ATOM   2574 O  O   . LEU   B 1 19  ? 33.42206  13.72043 -32.85133 1.000 90.71852  ? 16  LEU   B O   1 
ATOM   2575 C  CB  . LEU   B 1 19  ? 31.03243  11.64922 -32.47668 1.000 80.71414  ? 16  LEU   B CB  1 
ATOM   2576 C  CG  . LEU   B 1 19  ? 29.52342  11.39656 -32.46004 1.000 81.58158  ? 16  LEU   B CG  1 
ATOM   2577 C  CD1 . LEU   B 1 19  ? 29.18869  10.11268 -33.20084 1.000 86.97442  ? 16  LEU   B CD1 1 
ATOM   2578 C  CD2 . LEU   B 1 19  ? 28.99521  11.34562 -31.03660 1.000 83.96649  ? 16  LEU   B CD2 1 
ATOM   2579 N  N   . HIS   B 1 20  ? 33.86027  12.43603 -31.04918 1.000 89.19391  ? 17  HIS   B N   1 
ATOM   2580 C  CA  . HIS   B 1 20  ? 35.31048  12.54923 -31.13581 1.000 97.77750  ? 17  HIS   B CA  1 
ATOM   2581 C  C   . HIS   B 1 20  ? 35.88605  11.14530 -31.24603 1.000 106.12139 ? 17  HIS   B C   1 
ATOM   2582 O  O   . HIS   B 1 20  ? 35.68436  10.31798 -30.34964 1.000 100.72785 ? 17  HIS   B O   1 
ATOM   2583 C  CB  . HIS   B 1 20  ? 35.88445  13.28068 -29.91745 1.000 92.47218  ? 17  HIS   B CB  1 
ATOM   2584 C  CG  . HIS   B 1 20  ? 35.27368  14.62764 -29.67407 1.000 86.69348  ? 17  HIS   B CG  1 
ATOM   2585 N  ND1 . HIS   B 1 20  ? 35.80102  15.79102 -30.19293 1.000 92.03391  ? 17  HIS   B ND1 1 
ATOM   2586 C  CD2 . HIS   B 1 20  ? 34.18546  14.99649 -28.95644 1.000 80.62539  ? 17  HIS   B CD2 1 
ATOM   2587 C  CE1 . HIS   B 1 20  ? 35.05910  16.81690 -29.81382 1.000 84.05561  ? 17  HIS   B CE1 1 
ATOM   2588 N  NE2 . HIS   B 1 20  ? 34.07283  16.36194 -29.06174 1.000 80.08810  ? 17  HIS   B NE2 1 
ATOM   2589 N  N   . THR   B 1 21  ? 36.59191  10.87740 -32.34314 1.000 110.44208 ? 18  THR   B N   1 
ATOM   2590 C  CA  . THR   B 1 21  ? 37.17944  9.56085  -32.54772 1.000 112.69262 ? 18  THR   B CA  1 
ATOM   2591 C  C   . THR   B 1 21  ? 38.30112  9.32553  -31.54436 1.000 108.13024 ? 18  THR   B C   1 
ATOM   2592 O  O   . THR   B 1 21  ? 39.12532  10.20844 -31.29155 1.000 102.51048 ? 18  THR   B O   1 
ATOM   2593 C  CB  . THR   B 1 21  ? 37.71982  9.43078  -33.97427 1.000 109.41621 ? 18  THR   B CB  1 
ATOM   2594 O  OG1 . THR   B 1 21  ? 38.77810  10.37547 -34.17360 1.000 111.61896 ? 18  THR   B OG1 1 
ATOM   2595 C  CG2 . THR   B 1 21  ? 36.62528  9.70621  -34.99144 1.000 100.97635 ? 18  THR   B CG2 1 
ATOM   2596 N  N   . GLN   B 1 22  ? 38.32876  8.12519  -30.96745 1.000 105.88006 ? 19  GLN   B N   1 
ATOM   2597 C  CA  . GLN   B 1 22  ? 39.32730  7.78175  -29.96753 1.000 112.81713 ? 19  GLN   B CA  1 
ATOM   2598 C  C   . GLN   B 1 22  ? 39.79285  6.35040  -30.19240 1.000 124.51944 ? 19  GLN   B C   1 
ATOM   2599 O  O   . GLN   B 1 22  ? 39.02130  5.48954  -30.62240 1.000 127.59647 ? 19  GLN   B O   1 
ATOM   2600 C  CB  . GLN   B 1 22  ? 38.77418  7.92765  -28.53886 1.000 109.58305 ? 19  GLN   B CB  1 
ATOM   2601 C  CG  . GLN   B 1 22  ? 38.26611  9.32256  -28.19022 1.000 110.60865 ? 19  GLN   B CG  1 
ATOM   2602 C  CD  . GLN   B 1 22  ? 39.36618  10.36177 -28.13193 1.000 112.17752 ? 19  GLN   B CD  1 
ATOM   2603 O  OE1 . GLN   B 1 22  ? 40.40370  10.15045 -27.50565 1.000 115.79619 ? 19  GLN   B OE1 1 
ATOM   2604 N  NE2 . GLN   B 1 22  ? 39.14286  11.49626 -28.78731 1.000 111.12655 ? 19  GLN   B NE2 1 
ATOM   2605 N  N   . VAL   B 1 23  ? 41.06615  6.10712  -29.89440 1.000 129.08911 ? 20  VAL   B N   1 
ATOM   2606 C  CA  . VAL   B 1 23  ? 41.64866  4.77004  -29.88442 1.000 123.40453 ? 20  VAL   B CA  1 
ATOM   2607 C  C   . VAL   B 1 23  ? 41.88973  4.37431  -28.43481 1.000 120.16911 ? 20  VAL   B C   1 
ATOM   2608 O  O   . VAL   B 1 23  ? 42.32889  5.19723  -27.62330 1.000 123.86751 ? 20  VAL   B O   1 
ATOM   2609 C  CB  . VAL   B 1 23  ? 42.94373  4.70379  -30.71758 1.000 122.29953 ? 20  VAL   B CB  1 
ATOM   2610 C  CG1 . VAL   B 1 23  ? 42.62677  4.91466  -32.19138 1.000 105.98049 ? 20  VAL   B CG1 1 
ATOM   2611 C  CG2 . VAL   B 1 23  ? 43.94235  5.74571  -30.23790 1.000 119.74058 ? 20  VAL   B CG2 1 
ATOM   2612 N  N   . VAL   B 1 24  ? 41.59233  3.11967  -28.10531 1.000 119.82396 ? 21  VAL   B N   1 
ATOM   2613 C  CA  . VAL   B 1 24  ? 41.58304  2.65890  -26.72241 1.000 119.49472 ? 21  VAL   B CA  1 
ATOM   2614 C  C   . VAL   B 1 24  ? 42.43064  1.40012  -26.59152 1.000 126.22136 ? 21  VAL   B C   1 
ATOM   2615 O  O   . VAL   B 1 24  ? 42.35687  0.49417  -27.42969 1.000 131.29702 ? 21  VAL   B O   1 
ATOM   2616 C  CB  . VAL   B 1 24  ? 40.14158  2.40551  -26.22549 1.000 122.27776 ? 21  VAL   B CB  1 
ATOM   2617 C  CG1 . VAL   B 1 24  ? 39.38981  1.49703  -27.18844 1.000 127.99031 ? 21  VAL   B CG1 1 
ATOM   2618 C  CG2 . VAL   B 1 24  ? 40.14686  1.81701  -24.82113 1.000 121.75632 ? 21  VAL   B CG2 1 
ATOM   2619 N  N   . ASP   B 1 25  ? 43.25011  1.35858  -25.54096 1.000 124.70524 ? 22  ASP   B N   1 
ATOM   2620 C  CA  . ASP   B 1 25  ? 44.06026  0.18816  -25.23181 1.000 130.73489 ? 22  ASP   B CA  1 
ATOM   2621 C  C   . ASP   B 1 25  ? 43.18615  -0.89200 -24.60561 1.000 134.78566 ? 22  ASP   B C   1 
ATOM   2622 O  O   . ASP   B 1 25  ? 42.48017  -0.64267 -23.62203 1.000 127.04287 ? 22  ASP   B O   1 
ATOM   2623 C  CB  . ASP   B 1 25  ? 45.19703  0.56660  -24.28165 1.000 130.27802 ? 22  ASP   B CB  1 
ATOM   2624 C  CG  . ASP   B 1 25  ? 46.10833  -0.60473 -23.95418 1.000 133.30888 ? 22  ASP   B CG  1 
ATOM   2625 O  OD1 . ASP   B 1 25  ? 46.01536  -1.65567 -24.62453 1.000 140.17443 ? 22  ASP   B OD1 1 
ATOM   2626 O  OD2 . ASP   B 1 25  ? 46.91649  -0.47482 -23.01159 1.000 130.77659 ? 22  ASP   B OD2 1 
ATOM   2627 N  N   . MET   B 1 26  ? 43.24062  -2.09699 -25.17602 1.000 134.09041 ? 23  MET   B N   1 
ATOM   2628 C  CA  . MET   B 1 26  ? 42.40156  -3.19464 -24.71260 1.000 130.18213 ? 23  MET   B CA  1 
ATOM   2629 C  C   . MET   B 1 26  ? 42.82170  -3.73804 -23.35178 1.000 131.91259 ? 23  MET   B C   1 
ATOM   2630 O  O   . MET   B 1 26  ? 42.09910  -4.56878 -22.78993 1.000 135.44531 ? 23  MET   B O   1 
ATOM   2631 C  CB  . MET   B 1 26  ? 42.42225  -4.32571 -25.74352 1.000 132.20678 ? 23  MET   B CB  1 
ATOM   2632 C  CG  . MET   B 1 26  ? 41.08200  -5.00618 -25.96049 1.000 134.59529 ? 23  MET   B CG  1 
ATOM   2633 S  SD  . MET   B 1 26  ? 39.97022  -4.01007 -26.97222 1.000 145.94266 ? 23  MET   B SD  1 
ATOM   2634 C  CE  . MET   B 1 26  ? 38.55202  -5.09653 -27.09834 1.000 124.27314 ? 23  MET   B CE  1 
ATOM   2635 N  N   . SER   B 1 27  ? 43.95454  -3.29167 -22.80636 1.000 130.32815 ? 24  SER   B N   1 
ATOM   2636 C  CA  . SER   B 1 27  ? 44.44377  -3.78132 -21.52398 1.000 130.29281 ? 24  SER   B CA  1 
ATOM   2637 C  C   . SER   B 1 27  ? 44.12585  -2.86036 -20.35189 1.000 130.46095 ? 24  SER   B C   1 
ATOM   2638 O  O   . SER   B 1 27  ? 44.32542  -3.26330 -19.20096 1.000 123.76788 ? 24  SER   B O   1 
ATOM   2639 C  CB  . SER   B 1 27  ? 45.95931  -4.00887 -21.59172 1.000 128.06169 ? 24  SER   B CB  1 
ATOM   2640 O  OG  . SER   B 1 27  ? 46.64835  -2.79161 -21.81457 1.000 127.98508 ? 24  SER   B OG  1 
ATOM   2641 N  N   . MET   B 1 28  ? 43.65051  -1.64489 -20.60518 1.000 135.31962 ? 25  MET   B N   1 
ATOM   2642 C  CA  . MET   B 1 28  ? 43.30176  -0.70622 -19.54925 1.000 128.94299 ? 25  MET   B CA  1 
ATOM   2643 C  C   . MET   B 1 28  ? 41.79646  -0.47103 -19.51624 1.000 123.32265 ? 25  MET   B C   1 
ATOM   2644 O  O   . MET   B 1 28  ? 41.11729  -0.52585 -20.54563 1.000 118.00388 ? 25  MET   B O   1 
ATOM   2645 C  CB  . MET   B 1 28  ? 44.03121  0.62930  -19.73159 1.000 123.09789 ? 25  MET   B CB  1 
ATOM   2646 C  CG  . MET   B 1 28  ? 45.53593  0.50033  -19.89698 1.000 126.46129 ? 25  MET   B CG  1 
ATOM   2647 S  SD  . MET   B 1 28  ? 46.32930  2.08336  -20.23625 1.000 131.43094 ? 25  MET   B SD  1 
ATOM   2648 C  CE  . MET   B 1 28  ? 45.87407  3.01140  -18.77361 1.000 109.28946 ? 25  MET   B CE  1 
ATOM   2649 N  N   . THR   B 1 29  ? 41.28208  -0.20857 -18.31765 1.000 118.71156 ? 26  THR   B N   1 
ATOM   2650 C  CA  . THR   B 1 29  ? 39.87413  0.11740  -18.16488 1.000 117.61931 ? 26  THR   B CA  1 
ATOM   2651 C  C   . THR   B 1 29  ? 39.57671  1.48405  -18.77476 1.000 120.45618 ? 26  THR   B C   1 
ATOM   2652 O  O   . THR   B 1 29  ? 40.47340  2.29912  -19.01515 1.000 119.13264 ? 26  THR   B O   1 
ATOM   2653 C  CB  . THR   B 1 29  ? 39.46919  0.11404  -16.69083 1.000 113.08763 ? 26  THR   B CB  1 
ATOM   2654 O  OG1 . THR   B 1 29  ? 40.21295  1.11656  -15.98772 1.000 111.94255 ? 26  THR   B OG1 1 
ATOM   2655 C  CG2 . THR   B 1 29  ? 39.74439  -1.24066 -16.06551 1.000 114.47384 ? 26  THR   B CG2 1 
ATOM   2656 N  N   . TYR   B 1 30  ? 38.28852  1.72824  -19.02961 1.000 117.18901 ? 27  TYR   B N   1 
ATOM   2657 C  CA  . TYR   B 1 30  ? 37.88325  3.00713  -19.60216 1.000 107.57778 ? 27  TYR   B CA  1 
ATOM   2658 C  C   . TYR   B 1 30  ? 38.20778  4.16754  -18.66978 1.000 105.62864 ? 27  TYR   B C   1 
ATOM   2659 O  O   . TYR   B 1 30  ? 38.54777  5.26063  -19.13652 1.000 103.85931 ? 27  TYR   B O   1 
ATOM   2660 C  CB  . TYR   B 1 30  ? 36.38889  2.99116  -19.92382 1.000 103.53163 ? 27  TYR   B CB  1 
ATOM   2661 C  CG  . TYR   B 1 30  ? 36.03124  2.19135  -21.15589 1.000 103.54407 ? 27  TYR   B CG  1 
ATOM   2662 C  CD1 . TYR   B 1 30  ? 36.42650  2.60924  -22.41996 1.000 99.05425  ? 27  TYR   B CD1 1 
ATOM   2663 C  CD2 . TYR   B 1 30  ? 35.28576  1.02427  -21.05466 1.000 101.65328 ? 27  TYR   B CD2 1 
ATOM   2664 C  CE1 . TYR   B 1 30  ? 36.09832  1.88148  -23.54649 1.000 101.12972 ? 27  TYR   B CE1 1 
ATOM   2665 C  CE2 . TYR   B 1 30  ? 34.95161  0.29158  -22.17413 1.000 101.37933 ? 27  TYR   B CE2 1 
ATOM   2666 C  CZ  . TYR   B 1 30  ? 35.36026  0.72437  -23.41711 1.000 103.04834 ? 27  TYR   B CZ  1 
ATOM   2667 O  OH  . TYR   B 1 30  ? 35.02900  -0.00348 -24.53549 1.000 110.63238 ? 27  TYR   B OH  1 
ATOM   2668 N  N   . GLY   B 1 31  ? 38.11184  3.95188  -17.35384 1.000 106.05503 ? 28  GLY   B N   1 
ATOM   2669 C  CA  . GLY   B 1 31  ? 38.39233  5.02170  -16.41146 1.000 98.91808  ? 28  GLY   B CA  1 
ATOM   2670 C  C   . GLY   B 1 31  ? 39.84279  5.45521  -16.40246 1.000 104.40457 ? 28  GLY   B C   1 
ATOM   2671 O  O   . GLY   B 1 31  ? 40.14216  6.62617  -16.15000 1.000 98.53411  ? 28  GLY   B O   1 
ATOM   2672 N  N   . GLN   B 1 32  ? 40.76023  4.52889  -16.68178 1.000 109.55179 ? 29  GLN   B N   1 
ATOM   2673 C  CA  . GLN   B 1 32  ? 42.17786  4.85896  -16.72379 1.000 111.62806 ? 29  GLN   B CA  1 
ATOM   2674 C  C   . GLN   B 1 32  ? 42.55546  5.65524  -17.96374 1.000 105.62285 ? 29  GLN   B C   1 
ATOM   2675 O  O   . GLN   B 1 32  ? 43.64801  6.23073  -17.99989 1.000 112.60730 ? 29  GLN   B O   1 
ATOM   2676 C  CB  . GLN   B 1 32  ? 43.01426  3.58090  -16.65535 1.000 117.35383 ? 29  GLN   B CB  1 
ATOM   2677 C  CG  . GLN   B 1 32  ? 42.88849  2.82200  -15.34506 1.000 114.01424 ? 29  GLN   B CG  1 
ATOM   2678 C  CD  . GLN   B 1 32  ? 43.39602  1.39714  -15.44878 1.000 121.57896 ? 29  GLN   B CD  1 
ATOM   2679 O  OE1 . GLN   B 1 32  ? 43.49870  0.84061  -16.54223 1.000 123.41118 ? 29  GLN   B OE1 1 
ATOM   2680 N  NE2 . GLN   B 1 32  ? 43.71534  0.79796  -14.30760 1.000 118.05402 ? 29  GLN   B NE2 1 
ATOM   2681 N  N   . GLN   B 1 33  ? 41.68622  5.70329  -18.96942 1.000 104.08303 ? 30  GLN   B N   1 
ATOM   2682 C  CA  . GLN   B 1 33  ? 41.96545  6.39276  -20.22043 1.000 109.21316 ? 30  GLN   B CA  1 
ATOM   2683 C  C   . GLN   B 1 33  ? 41.02451  7.55314  -20.50718 1.000 108.60631 ? 30  GLN   B C   1 
ATOM   2684 O  O   . GLN   B 1 33  ? 41.44120  8.51912  -21.15160 1.000 107.31306 ? 30  GLN   B O   1 
ATOM   2685 C  CB  . GLN   B 1 33  ? 41.90079  5.40120  -21.39227 1.000 104.70109 ? 30  GLN   B CB  1 
ATOM   2686 C  CG  . GLN   B 1 33  ? 42.68639  4.12291  -21.15448 1.000 111.07662 ? 30  GLN   B CG  1 
ATOM   2687 C  CD  . GLN   B 1 33  ? 42.27846  3.00439  -22.09193 1.000 117.23687 ? 30  GLN   B CD  1 
ATOM   2688 O  OE1 . GLN   B 1 33  ? 42.77453  2.90759  -23.21467 1.000 114.40986 ? 30  GLN   B OE1 1 
ATOM   2689 N  NE2 . GLN   B 1 33  ? 41.36988  2.15043  -21.63394 1.000 117.45446 ? 30  GLN   B NE2 1 
ATOM   2690 N  N   . PHE   B 1 34  ? 39.77209  7.48550  -20.04938 1.000 107.59498 ? 31  PHE   B N   1 
ATOM   2691 C  CA  . PHE   B 1 34  ? 38.78530  8.52665  -20.29390 1.000 98.31490  ? 31  PHE   B CA  1 
ATOM   2692 C  C   . PHE   B 1 34  ? 38.22339  9.15866  -19.02893 1.000 94.98426  ? 31  PHE   B C   1 
ATOM   2693 O  O   . PHE   B 1 34  ? 37.54270  10.18631 -19.12533 1.000 97.78798  ? 31  PHE   B O   1 
ATOM   2694 C  CB  . PHE   B 1 34  ? 37.61273  7.96597  -21.11529 1.000 99.07476  ? 31  PHE   B CB  1 
ATOM   2695 C  CG  . PHE   B 1 34  ? 37.99663  7.50605  -22.49229 1.000 99.33095  ? 31  PHE   B CG  1 
ATOM   2696 C  CD1 . PHE   B 1 34  ? 39.03611  8.11132  -23.17681 1.000 94.87525  ? 31  PHE   B CD1 1 
ATOM   2697 C  CD2 . PHE   B 1 34  ? 37.31884  6.46232  -23.09928 1.000 97.53793  ? 31  PHE   B CD2 1 
ATOM   2698 C  CE1 . PHE   B 1 34  ? 39.38895  7.68829  -24.44373 1.000 103.11874 ? 31  PHE   B CE1 1 
ATOM   2699 C  CE2 . PHE   B 1 34  ? 37.66773  6.03417  -24.36505 1.000 101.19188 ? 31  PHE   B CE2 1 
ATOM   2700 C  CZ  . PHE   B 1 34  ? 38.70407  6.64786  -25.03849 1.000 102.33553 ? 31  PHE   B CZ  1 
ATOM   2701 N  N   . GLY   B 1 35  ? 38.48174  8.58814  -17.85658 1.000 89.51727  ? 32  GLY   B N   1 
ATOM   2702 C  CA  . GLY   B 1 35  ? 37.78273  8.98160  -16.65850 1.000 89.68541  ? 32  GLY   B CA  1 
ATOM   2703 C  C   . GLY   B 1 35  ? 36.44519  8.27625  -16.58737 1.000 93.54019  ? 32  GLY   B C   1 
ATOM   2704 O  O   . GLY   B 1 35  ? 36.24518  7.23027  -17.21285 1.000 93.14193  ? 32  GLY   B O   1 
ATOM   2705 N  N   . PRO   B 1 36  ? 35.50252  8.82826  -15.82408 1.000 88.70295  ? 33  PRO   B N   1 
ATOM   2706 C  CA  . PRO   B 1 36  ? 34.15872  8.23586  -15.77585 1.000 86.66055  ? 33  PRO   B CA  1 
ATOM   2707 C  C   . PRO   B 1 36  ? 33.55798  8.12320  -17.17025 1.000 90.46327  ? 33  PRO   B C   1 
ATOM   2708 O  O   . PRO   B 1 36  ? 33.48502  9.10249  -17.91523 1.000 90.48368  ? 33  PRO   B O   1 
ATOM   2709 C  CB  . PRO   B 1 36  ? 33.37300  9.21321  -14.89477 1.000 78.85532  ? 33  PRO   B CB  1 
ATOM   2710 C  CG  . PRO   B 1 36  ? 34.41090  9.87077  -14.05048 1.000 75.87122  ? 33  PRO   B CG  1 
ATOM   2711 C  CD  . PRO   B 1 36  ? 35.63163  9.98321  -14.91890 1.000 77.23575  ? 33  PRO   B CD  1 
ATOM   2712 N  N   . THR   B 1 37  ? 33.13156  6.90995  -17.51843 1.000 86.90276  ? 34  THR   B N   1 
ATOM   2713 C  CA  . THR   B 1 37  ? 32.65327  6.60082  -18.85738 1.000 84.29958  ? 34  THR   B CA  1 
ATOM   2714 C  C   . THR   B 1 37  ? 31.38345  5.77046  -18.75684 1.000 90.70612  ? 34  THR   B C   1 
ATOM   2715 O  O   . THR   B 1 37  ? 31.26497  4.90595  -17.88452 1.000 94.86938  ? 34  THR   B O   1 
ATOM   2716 C  CB  . THR   B 1 37  ? 33.71539  5.84745  -19.67108 1.000 90.17968  ? 34  THR   B CB  1 
ATOM   2717 O  OG1 . THR   B 1 37  ? 34.94394  6.58396  -19.64669 1.000 100.09838 ? 34  THR   B OG1 1 
ATOM   2718 C  CG2 . THR   B 1 37  ? 33.27051  5.68025  -21.11658 1.000 90.72583  ? 34  THR   B CG2 1 
ATOM   2719 N  N   . TYR   B 1 38  ? 30.43496  6.04167  -19.65040 1.000 93.81408  ? 35  TYR   B N   1 
ATOM   2720 C  CA  . TYR   B 1 38  ? 29.13589  5.38934  -19.63689 1.000 88.31903  ? 35  TYR   B CA  1 
ATOM   2721 C  C   . TYR   B 1 38  ? 28.77462  4.93210  -21.04127 1.000 89.21805  ? 35  TYR   B C   1 
ATOM   2722 O  O   . TYR   B 1 38  ? 29.14818  5.56325  -22.03412 1.000 85.41767  ? 35  TYR   B O   1 
ATOM   2723 C  CB  . TYR   B 1 38  ? 28.04000  6.31973  -19.10838 1.000 84.08460  ? 35  TYR   B CB  1 
ATOM   2724 C  CG  . TYR   B 1 38  ? 28.34404  6.94540  -17.76787 1.000 81.65115  ? 35  TYR   B CG  1 
ATOM   2725 C  CD1 . TYR   B 1 38  ? 29.07991  8.12004  -17.68200 1.000 84.12421  ? 35  TYR   B CD1 1 
ATOM   2726 C  CD2 . TYR   B 1 38  ? 27.88091  6.37471  -16.58968 1.000 80.93638  ? 35  TYR   B CD2 1 
ATOM   2727 C  CE1 . TYR   B 1 38  ? 29.35703  8.70297  -16.46210 1.000 81.22862  ? 35  TYR   B CE1 1 
ATOM   2728 C  CE2 . TYR   B 1 38  ? 28.15179  6.95389  -15.36146 1.000 74.95993  ? 35  TYR   B CE2 1 
ATOM   2729 C  CZ  . TYR   B 1 38  ? 28.89166  8.11949  -15.30624 1.000 73.88220  ? 35  TYR   B CZ  1 
ATOM   2730 O  OH  . TYR   B 1 38  ? 29.17405  8.71200  -14.09765 1.000 71.43746  ? 35  TYR   B OH  1 
ATOM   2731 N  N   . LEU   B 1 39  ? 28.04356  3.82178  -21.11345 1.000 95.65601  ? 36  LEU   B N   1 
ATOM   2732 C  CA  . LEU   B 1 39  ? 27.53588  3.28837  -22.37623 1.000 102.77754 ? 36  LEU   B CA  1 
ATOM   2733 C  C   . LEU   B 1 39  ? 26.03560  3.07913  -22.19204 1.000 104.82053 ? 36  LEU   B C   1 
ATOM   2734 O  O   . LEU   B 1 39  ? 25.61629  2.13440  -21.51510 1.000 103.10986 ? 36  LEU   B O   1 
ATOM   2735 C  CB  . LEU   B 1 39  ? 28.25309  1.99315  -22.75994 1.000 96.93406  ? 36  LEU   B CB  1 
ATOM   2736 C  CG  . LEU   B 1 39  ? 27.98154  1.33731  -24.12214 1.000 93.48738  ? 36  LEU   B CG  1 
ATOM   2737 C  CD1 . LEU   B 1 39  ? 26.70383  0.50477  -24.14622 1.000 96.40746  ? 36  LEU   B CD1 1 
ATOM   2738 C  CD2 . LEU   B 1 39  ? 27.95306  2.39033  -25.21965 1.000 93.74614  ? 36  LEU   B CD2 1 
ATOM   2739 N  N   . ASP   B 1 40  ? 25.23788  3.97339  -22.78210 1.000 100.10249 ? 37  ASP   B N   1 
ATOM   2740 C  CA  . ASP   B 1 40  ? 23.77726  3.92988  -22.68143 1.000 101.59553 ? 37  ASP   B CA  1 
ATOM   2741 C  C   . ASP   B 1 40  ? 23.31889  3.91933  -21.22291 1.000 96.15338  ? 37  ASP   B C   1 
ATOM   2742 O  O   . ASP   B 1 40  ? 22.44413  3.14766  -20.82455 1.000 98.31767  ? 37  ASP   B O   1 
ATOM   2743 C  CB  . ASP   B 1 40  ? 23.20802  2.73574  -23.44930 1.000 99.17210  ? 37  ASP   B CB  1 
ATOM   2744 C  CG  . ASP   B 1 40  ? 23.14459  2.98776  -24.93791 1.000 123.68256 ? 37  ASP   B CG  1 
ATOM   2745 O  OD1 . ASP   B 1 40  ? 22.54186  4.00663  -25.33822 1.000 134.26971 ? 37  ASP   B OD1 1 
ATOM   2746 O  OD2 . ASP   B 1 40  ? 23.70604  2.17819  -25.70627 1.000 130.17480 ? 37  ASP   B OD2 1 
ATOM   2747 N  N   . GLY   B 1 41  ? 23.93029  4.78622  -20.41769 1.000 93.36491  ? 38  GLY   B N   1 
ATOM   2748 C  CA  . GLY   B 1 41  ? 23.60183  4.88673  -19.01269 1.000 90.91463  ? 38  GLY   B CA  1 
ATOM   2749 C  C   . GLY   B 1 41  ? 24.30027  3.89421  -18.10923 1.000 94.00728  ? 38  GLY   B C   1 
ATOM   2750 O  O   . GLY   B 1 41  ? 24.28153  4.07991  -16.88627 1.000 88.71622  ? 38  GLY   B O   1 
ATOM   2751 N  N   . ALA   B 1 42  ? 24.91448  2.84835  -18.66187 1.000 102.82862 ? 39  ALA   B N   1 
ATOM   2752 C  CA  . ALA   B 1 42  ? 25.62276  1.84958  -17.87082 1.000 101.86557 ? 39  ALA   B CA  1 
ATOM   2753 C  C   . ALA   B 1 42  ? 27.04191  2.33161  -17.59731 1.000 101.81628 ? 39  ALA   B C   1 
ATOM   2754 O  O   . ALA   B 1 42  ? 27.74274  2.76990  -18.51582 1.000 99.36649  ? 39  ALA   B O   1 
ATOM   2755 C  CB  . ALA   B 1 42  ? 25.65372  0.50291  -18.59567 1.000 98.71784  ? 39  ALA   B CB  1 
ATOM   2756 N  N   . ASP   B 1 43  ? 27.46202  2.23893  -16.33677 1.000 100.17316 ? 40  ASP   B N   1 
ATOM   2757 C  CA  . ASP   B 1 43  ? 28.79263  2.67703  -15.93173 1.000 96.78763  ? 40  ASP   B CA  1 
ATOM   2758 C  C   . ASP   B 1 43  ? 29.81932  1.63752  -16.36576 1.000 93.16437  ? 40  ASP   B C   1 
ATOM   2759 O  O   . ASP   B 1 43  ? 29.76183  0.48085  -15.93448 1.000 98.10762  ? 40  ASP   B O   1 
ATOM   2760 C  CB  . ASP   B 1 43  ? 28.84315  2.89435  -14.41844 1.000 93.21777  ? 40  ASP   B CB  1 
ATOM   2761 C  CG  . ASP   B 1 43  ? 30.08100  3.66360  -13.97126 1.000 97.42934  ? 40  ASP   B CG  1 
ATOM   2762 O  OD1 . ASP   B 1 43  ? 31.07835  3.68700  -14.72197 1.000 101.76906 ? 40  ASP   B OD1 1 
ATOM   2763 O  OD2 . ASP   B 1 43  ? 30.05826  4.24583  -12.86400 1.000 83.61929  ? 40  ASP   B OD2 1 
ATOM   2764 N  N   . VAL   B 1 44  ? 30.75837  2.04800  -17.21376 1.000 84.39794  ? 41  VAL   B N   1 
ATOM   2765 C  CA  . VAL   B 1 44  ? 31.81582  1.17019  -17.69336 1.000 91.97997  ? 41  VAL   B CA  1 
ATOM   2766 C  C   . VAL   B 1 44  ? 33.19394  1.71249  -17.32064 1.000 96.77125  ? 41  VAL   B C   1 
ATOM   2767 O  O   . VAL   B 1 44  ? 34.18253  1.41382  -17.98520 1.000 93.62455  ? 41  VAL   B O   1 
ATOM   2768 C  CB  . VAL   B 1 44  ? 31.69675  0.93500  -19.21145 1.000 94.93308  ? 41  VAL   B CB  1 
ATOM   2769 C  CG1 . VAL   B 1 44  ? 30.37794  0.25570  -19.53456 1.000 89.27659  ? 41  VAL   B CG1 1 
ATOM   2770 C  CG2 . VAL   B 1 44  ? 31.82404  2.25148  -19.97094 1.000 95.02206  ? 41  VAL   B CG2 1 
ATOM   2771 N  N   . THR   B 1 45  ? 33.25975  2.51751  -16.25610 1.000 93.80849  ? 42  THR   B N   1 
ATOM   2772 C  CA  . THR   B 1 45  ? 34.53175  3.09008  -15.82531 1.000 99.86587  ? 42  THR   B CA  1 
ATOM   2773 C  C   . THR   B 1 45  ? 35.51606  1.99524  -15.43164 1.000 109.43653 ? 42  THR   B C   1 
ATOM   2774 O  O   . THR   B 1 45  ? 36.67204  1.99353  -15.87112 1.000 112.52103 ? 42  THR   B O   1 
ATOM   2775 C  CB  . THR   B 1 45  ? 34.30319  4.05868  -14.66224 1.000 102.02195 ? 42  THR   B CB  1 
ATOM   2776 O  OG1 . THR   B 1 45  ? 33.40353  5.09753  -15.07062 1.000 95.98998  ? 42  THR   B OG1 1 
ATOM   2777 C  CG2 . THR   B 1 45  ? 35.61563  4.68026  -14.21036 1.000 100.99151 ? 42  THR   B CG2 1 
ATOM   2778 N  N   . LYS   B 1 46  ? 35.07118  1.05104  -14.61063 1.000 107.43975 ? 43  LYS   B N   1 
ATOM   2779 C  CA  . LYS   B 1 46  ? 35.90536  -0.06536 -14.16432 1.000 104.89906 ? 43  LYS   B CA  1 
ATOM   2780 C  C   . LYS   B 1 46  ? 35.59130  -1.33168 -14.95243 1.000 106.70594 ? 43  LYS   B C   1 
ATOM   2781 O  O   . LYS   B 1 46  ? 35.42087  -2.41516 -14.39416 1.000 110.57941 ? 43  LYS   B O   1 
ATOM   2782 C  CB  . LYS   B 1 46  ? 35.72504  -0.28685 -12.66724 1.000 101.53987 ? 43  LYS   B CB  1 
ATOM   2783 C  CG  . LYS   B 1 46  ? 36.21683  0.87642  -11.81695 1.000 105.65044 ? 43  LYS   B CG  1 
ATOM   2784 C  CD  . LYS   B 1 46  ? 36.12386  0.57363  -10.33029 1.000 103.68500 ? 43  LYS   B CD  1 
ATOM   2785 C  CE  . LYS   B 1 46  ? 34.67969  0.44251  -9.87730  1.000 107.27944 ? 43  LYS   B CE  1 
ATOM   2786 N  NZ  . LYS   B 1 46  ? 34.57912  0.24396  -8.40374  1.000 113.14571 ? 43  LYS   B NZ  1 
ATOM   2787 N  N   . ILE   B 1 47  ? 35.50598  -1.19723 -16.27402 1.000 102.03384 ? 44  ILE   B N   1 
ATOM   2788 C  CA  . ILE   B 1 47  ? 35.23246  -2.30985 -17.17523 1.000 107.75556 ? 44  ILE   B CA  1 
ATOM   2789 C  C   . ILE   B 1 47  ? 36.21835  -2.23935 -18.33302 1.000 109.29805 ? 44  ILE   B C   1 
ATOM   2790 O  O   . ILE   B 1 47  ? 36.39539  -1.17561 -18.93736 1.000 110.91141 ? 44  ILE   B O   1 
ATOM   2791 C  CB  . ILE   B 1 47  ? 33.77737  -2.27856 -17.68961 1.000 109.23687 ? 44  ILE   B CB  1 
ATOM   2792 C  CG1 . ILE   B 1 47  ? 32.81427  -2.79133 -16.61537 1.000 100.62477 ? 44  ILE   B CG1 1 
ATOM   2793 C  CG2 . ILE   B 1 47  ? 33.62536  -3.08273 -18.97834 1.000 97.87396  ? 44  ILE   B CG2 1 
ATOM   2794 C  CD1 . ILE   B 1 47  ? 32.99366  -4.25582 -16.27869 1.000 107.20892 ? 44  ILE   B CD1 1 
ATOM   2795 N  N   . LYS   B 1 48  ? 36.86822  -3.36642 -18.63352 1.000 113.93947 ? 45  LYS   B N   1 
ATOM   2796 C  CA  . LYS   B 1 48  ? 37.74699  -3.42657 -19.79059 1.000 114.48937 ? 45  LYS   B CA  1 
ATOM   2797 C  C   . LYS   B 1 48  ? 36.94052  -3.50063 -21.08588 1.000 112.81225 ? 45  LYS   B C   1 
ATOM   2798 O  O   . LYS   B 1 48  ? 35.83802  -4.05547 -21.11136 1.000 114.33595 ? 45  LYS   B O   1 
ATOM   2799 C  CB  . LYS   B 1 48  ? 38.68217  -4.62931 -19.70620 1.000 122.88610 ? 45  LYS   B CB  1 
ATOM   2800 C  CG  . LYS   B 1 48  ? 40.10207  -4.29800 -19.26593 1.000 125.12745 ? 45  LYS   B CG  1 
ATOM   2801 C  CD  . LYS   B 1 48  ? 40.30165  -4.39925 -17.76699 1.000 122.26474 ? 45  LYS   B CD  1 
ATOM   2802 C  CE  . LYS   B 1 48  ? 41.75890  -4.13353 -17.40818 1.000 120.04690 ? 45  LYS   B CE  1 
ATOM   2803 N  NZ  . LYS   B 1 48  ? 42.03526  -4.27674 -15.95148 1.000 122.31868 ? 45  LYS   B NZ  1 
ATOM   2804 N  N   . PRO   B 1 49  ? 37.47224  -2.94195 -22.17131 1.000 112.45768 ? 46  PRO   B N   1 
ATOM   2805 C  CA  . PRO   B 1 49  ? 36.74183  -2.95295 -23.44518 1.000 115.27971 ? 46  PRO   B CA  1 
ATOM   2806 C  C   . PRO   B 1 49  ? 36.54884  -4.36794 -23.97082 1.000 121.96595 ? 46  PRO   B C   1 
ATOM   2807 O  O   . PRO   B 1 49  ? 37.47839  -5.17820 -23.98320 1.000 127.85356 ? 46  PRO   B O   1 
ATOM   2808 C  CB  . PRO   B 1 49  ? 37.63900  -2.12685 -24.37586 1.000 112.59434 ? 46  PRO   B CB  1 
ATOM   2809 C  CG  . PRO   B 1 49  ? 38.50391  -1.31988 -23.46828 1.000 112.96252 ? 46  PRO   B CG  1 
ATOM   2810 C  CD  . PRO   B 1 49  ? 38.72490  -2.17404 -22.26064 1.000 115.31763 ? 46  PRO   B CD  1 
ATOM   2811 N  N   . HIS   B 1 50  ? 35.32461  -4.66202 -24.39579 1.000 124.97148 ? 47  HIS   B N   1 
ATOM   2812 C  CA  . HIS   B 1 50  ? 35.02694  -5.90628 -25.08425 1.000 120.12265 ? 47  HIS   B CA  1 
ATOM   2813 C  C   . HIS   B 1 50  ? 35.12106  -5.68482 -26.59262 1.000 117.80748 ? 47  HIS   B C   1 
ATOM   2814 O  O   . HIS   B 1 50  ? 35.23941  -4.55629 -27.07597 1.000 116.51477 ? 47  HIS   B O   1 
ATOM   2815 C  CB  . HIS   B 1 50  ? 33.63684  -6.42696 -24.70586 1.000 119.04296 ? 47  HIS   B CB  1 
ATOM   2816 C  CG  . HIS   B 1 50  ? 33.52449  -6.89865 -23.28694 1.000 126.52685 ? 47  HIS   B CG  1 
ATOM   2817 N  ND1 . HIS   B 1 50  ? 32.33665  -6.87168 -22.58712 1.000 127.70770 ? 47  HIS   B ND1 1 
ATOM   2818 C  CD2 . HIS   B 1 50  ? 34.45163  -7.39560 -22.43342 1.000 124.41929 ? 47  HIS   B CD2 1 
ATOM   2819 C  CE1 . HIS   B 1 50  ? 32.53474  -7.34099 -21.36796 1.000 125.80309 ? 47  HIS   B CE1 1 
ATOM   2820 N  NE2 . HIS   B 1 50  ? 33.80986  -7.66420 -21.24834 1.000 128.32136 ? 47  HIS   B NE2 1 
ATOM   2821 N  N   . ASN   B 1 51  ? 35.07789  -6.78611 -27.34459 1.000 123.25352 ? 48  ASN   B N   1 
ATOM   2822 C  CA  . ASN   B 1 51  ? 35.21172  -6.67783 -28.79312 1.000 114.66127 ? 48  ASN   B CA  1 
ATOM   2823 C  C   . ASN   B 1 51  ? 33.97653  -6.04230 -29.41839 1.000 122.09986 ? 48  ASN   B C   1 
ATOM   2824 O  O   . ASN   B 1 51  ? 34.07486  -5.40149 -30.47200 1.000 116.05436 ? 48  ASN   B O   1 
ATOM   2825 C  CB  . ASN   B 1 51  ? 35.47236  -8.05577 -29.40257 1.000 109.35912 ? 48  ASN   B CB  1 
ATOM   2826 N  N   . SER   B 1 52  ? 32.81204  -6.20425 -28.78554 1.000 122.90897 ? 49  SER   B N   1 
ATOM   2827 C  CA  . SER   B 1 52  ? 31.58233  -5.58744 -29.26849 1.000 124.59077 ? 49  SER   B CA  1 
ATOM   2828 C  C   . SER   B 1 52  ? 31.57120  -4.07228 -29.10873 1.000 128.25765 ? 49  SER   B C   1 
ATOM   2829 O  O   . SER   B 1 52  ? 30.71453  -3.41358 -29.70802 1.000 128.38759 ? 49  SER   B O   1 
ATOM   2830 C  CB  . SER   B 1 52  ? 30.37558  -6.18800 -28.54583 1.000 115.83041 ? 49  SER   B CB  1 
ATOM   2831 O  OG  . SER   B 1 52  ? 30.49125  -6.02786 -27.14283 1.000 117.10605 ? 49  SER   B OG  1 
ATOM   2832 N  N   . HIS   B 1 53  ? 32.48931  -3.50497 -28.32658 1.000 122.41835 ? 50  HIS   B N   1 
ATOM   2833 C  CA  . HIS   B 1 53  ? 32.53490  -2.06167 -28.12697 1.000 114.76704 ? 50  HIS   B CA  1 
ATOM   2834 C  C   . HIS   B 1 53  ? 33.16390  -1.31917 -29.29977 1.000 125.54801 ? 50  HIS   B C   1 
ATOM   2835 O  O   . HIS   B 1 53  ? 33.31230  -0.09458 -29.22806 1.000 126.12612 ? 50  HIS   B O   1 
ATOM   2836 C  CB  . HIS   B 1 53  ? 33.29159  -1.73108 -26.83748 1.000 107.24688 ? 50  HIS   B CB  1 
ATOM   2837 C  CG  . HIS   B 1 53  ? 32.63845  -2.26408 -25.59992 1.000 110.84222 ? 50  HIS   B CG  1 
ATOM   2838 N  ND1 . HIS   B 1 53  ? 33.20849  -2.15122 -24.34957 1.000 111.62390 ? 50  HIS   B ND1 1 
ATOM   2839 C  CD2 . HIS   B 1 53  ? 31.46073  -2.90842 -25.41939 1.000 113.94528 ? 50  HIS   B CD2 1 
ATOM   2840 C  CE1 . HIS   B 1 53  ? 32.41182  -2.70556 -23.45277 1.000 116.62326 ? 50  HIS   B CE1 1 
ATOM   2841 N  NE2 . HIS   B 1 53  ? 31.34440  -3.17257 -24.07576 1.000 117.21213 ? 50  HIS   B NE2 1 
ATOM   2842 N  N   . GLU   B 1 54  ? 33.53647  -2.02416 -30.36543 1.000 122.75026 ? 51  GLU   B N   1 
ATOM   2843 C  CA  . GLU   B 1 54  ? 34.12392  -1.39127 -31.53990 1.000 119.59339 ? 51  GLU   B CA  1 
ATOM   2844 C  C   . GLU   B 1 54  ? 33.09550  -0.50949 -32.23938 1.000 122.23299 ? 51  GLU   B C   1 
ATOM   2845 O  O   . GLU   B 1 54  ? 32.06414  -1.00033 -32.70971 1.000 126.48463 ? 51  GLU   B O   1 
ATOM   2846 C  CB  . GLU   B 1 54  ? 34.65436  -2.45842 -32.49578 1.000 126.21444 ? 51  GLU   B CB  1 
ATOM   2847 C  CG  . GLU   B 1 54  ? 35.00408  -1.94727 -33.89141 1.000 132.88438 ? 51  GLU   B CG  1 
ATOM   2848 C  CD  . GLU   B 1 54  ? 36.30708  -1.17310 -33.94122 1.000 133.86603 ? 51  GLU   B CD  1 
ATOM   2849 O  OE1 . GLU   B 1 54  ? 37.10852  -1.28597 -32.98987 1.000 132.72006 ? 51  GLU   B OE1 1 
ATOM   2850 O  OE2 . GLU   B 1 54  ? 36.53005  -0.45317 -34.93946 1.000 124.49683 ? 51  GLU   B OE2 1 
ATOM   2851 N  N   . GLY   B 1 55  ? 33.37398  0.79364  -32.30230 1.000 118.00801 ? 52  GLY   B N   1 
ATOM   2852 C  CA  . GLY   B 1 55  ? 32.54888  1.73016  -33.03563 1.000 115.25810 ? 52  GLY   B CA  1 
ATOM   2853 C  C   . GLY   B 1 55  ? 31.42212  2.37170  -32.25364 1.000 118.51617 ? 52  GLY   B C   1 
ATOM   2854 O  O   . GLY   B 1 55  ? 30.80355  3.31874  -32.75863 1.000 106.80602 ? 52  GLY   B O   1 
ATOM   2855 N  N   . LYS   B 1 56  ? 31.13351  1.89762  -31.04543 1.000 117.92208 ? 53  LYS   B N   1 
ATOM   2856 C  CA  . LYS   B 1 56  ? 30.04565  2.46381  -30.26582 1.000 112.83861 ? 53  LYS   B CA  1 
ATOM   2857 C  C   . LYS   B 1 56  ? 30.45497  3.81143  -29.67289 1.000 113.55103 ? 53  LYS   B C   1 
ATOM   2858 O  O   . LYS   B 1 56  ? 31.64021  4.13136  -29.54067 1.000 110.78147 ? 53  LYS   B O   1 
ATOM   2859 C  CB  . LYS   B 1 56  ? 29.62281  1.50027  -29.15543 1.000 106.59840 ? 53  LYS   B CB  1 
ATOM   2860 N  N   . THR   B 1 57  ? 29.44934  4.60650  -29.31690 1.000 107.35347 ? 54  THR   B N   1 
ATOM   2861 C  CA  . THR   B 1 57  ? 29.65471  5.93982  -28.76636 1.000 99.43518  ? 54  THR   B CA  1 
ATOM   2862 C  C   . THR   B 1 57  ? 29.51874  5.88582  -27.25033 1.000 100.08843 ? 54  THR   B C   1 
ATOM   2863 O  O   . THR   B 1 57  ? 28.58835  5.26386  -26.72676 1.000 95.92611  ? 54  THR   B O   1 
ATOM   2864 C  CB  . THR   B 1 57  ? 28.65661  6.94187  -29.35228 1.000 99.41759  ? 54  THR   B CB  1 
ATOM   2865 O  OG1 . THR   B 1 57  ? 27.32469  6.56908  -28.98048 1.000 112.33113 ? 54  THR   B OG1 1 
ATOM   2866 C  CG2 . THR   B 1 57  ? 28.75877  6.97525  -30.87187 1.000 103.88871 ? 54  THR   B CG2 1 
ATOM   2867 N  N   . PHE   B 1 58  ? 30.44392  6.53734  -26.55203 1.000 97.09031  ? 55  PHE   B N   1 
ATOM   2868 C  CA  . PHE   B 1 58  ? 30.47450  6.54506  -25.09730 1.000 93.77134  ? 55  PHE   B CA  1 
ATOM   2869 C  C   . PHE   B 1 58  ? 30.34210  7.96891  -24.57708 1.000 85.70405  ? 55  PHE   B C   1 
ATOM   2870 O  O   . PHE   B 1 58  ? 30.92728  8.90199  -25.13542 1.000 86.39684  ? 55  PHE   B O   1 
ATOM   2871 C  CB  . PHE   B 1 58  ? 31.77391  5.92875  -24.56390 1.000 100.88993 ? 55  PHE   B CB  1 
ATOM   2872 C  CG  . PHE   B 1 58  ? 31.87757  4.44516  -24.77035 1.000 99.35761  ? 55  PHE   B CG  1 
ATOM   2873 C  CD1 . PHE   B 1 58  ? 32.38070  3.92735  -25.95354 1.000 98.99520  ? 55  PHE   B CD1 1 
ATOM   2874 C  CD2 . PHE   B 1 58  ? 31.48297  3.56757  -23.77354 1.000 97.22932  ? 55  PHE   B CD2 1 
ATOM   2875 C  CE1 . PHE   B 1 58  ? 32.48007  2.56112  -26.14117 1.000 100.52098 ? 55  PHE   B CE1 1 
ATOM   2876 C  CE2 . PHE   B 1 58  ? 31.58044  2.20210  -23.95338 1.000 100.30840 ? 55  PHE   B CE2 1 
ATOM   2877 C  CZ  . PHE   B 1 58  ? 32.07902  1.69766  -25.13931 1.000 108.09833 ? 55  PHE   B CZ  1 
ATOM   2878 N  N   . TYR   B 1 59  ? 29.56865  8.12827  -23.50680 1.000 74.39861  ? 56  TYR   B N   1 
ATOM   2879 C  CA  . TYR   B 1 59  ? 29.51752  9.39274  -22.78741 1.000 86.63602  ? 56  TYR   B CA  1 
ATOM   2880 C  C   . TYR   B 1 59  ? 30.66775  9.45627  -21.79160 1.000 88.43205  ? 56  TYR   B C   1 
ATOM   2881 O  O   . TYR   B 1 59  ? 30.92878  8.48873  -21.07090 1.000 88.18601  ? 56  TYR   B O   1 
ATOM   2882 C  CB  . TYR   B 1 59  ? 28.18596  9.54572  -22.05109 1.000 83.98356  ? 56  TYR   B CB  1 
ATOM   2883 C  CG  . TYR   B 1 59  ? 27.02219  10.00361 -22.90199 1.000 88.57929  ? 56  TYR   B CG  1 
ATOM   2884 C  CD1 . TYR   B 1 59  ? 26.42378  9.15389  -23.82377 1.000 94.75438  ? 56  TYR   B CD1 1 
ATOM   2885 C  CD2 . TYR   B 1 59  ? 26.50565  11.28520 -22.76184 1.000 85.71237  ? 56  TYR   B CD2 1 
ATOM   2886 C  CE1 . TYR   B 1 59  ? 25.35056  9.57666  -24.59394 1.000 97.93803  ? 56  TYR   B CE1 1 
ATOM   2887 C  CE2 . TYR   B 1 59  ? 25.43717  11.71506 -23.52333 1.000 92.02930  ? 56  TYR   B CE2 1 
ATOM   2888 C  CZ  . TYR   B 1 59  ? 24.86254  10.85928 -24.43729 1.000 99.25420  ? 56  TYR   B CZ  1 
ATOM   2889 O  OH  . TYR   B 1 59  ? 23.79630  11.29148 -25.19229 1.000 94.17997  ? 56  TYR   B OH  1 
ATOM   2890 N  N   . VAL   B 1 60  ? 31.35483  10.59412 -21.74865 1.000 85.35190  ? 57  VAL   B N   1 
ATOM   2891 C  CA  . VAL   B 1 60  ? 32.46263  10.79048 -20.82514 1.000 77.11820  ? 57  VAL   B CA  1 
ATOM   2892 C  C   . VAL   B 1 60  ? 32.26904  12.11743 -20.10835 1.000 77.26019  ? 57  VAL   B C   1 
ATOM   2893 O  O   . VAL   B 1 60  ? 31.74066  13.08049 -20.67318 1.000 81.29997  ? 57  VAL   B O   1 
ATOM   2894 C  CB  . VAL   B 1 60  ? 33.83144  10.75459 -21.54410 1.000 79.13322  ? 57  VAL   B CB  1 
ATOM   2895 C  CG1 . VAL   B 1 60  ? 34.03663  9.41918  -22.24012 1.000 83.66075  ? 57  VAL   B CG1 1 
ATOM   2896 C  CG2 . VAL   B 1 60  ? 33.93756  11.89040 -22.54670 1.000 78.13429  ? 57  VAL   B CG2 1 
ATOM   2897 N  N   . LEU   B 1 61  ? 32.68191  12.15646 -18.84582 1.000 80.38870  ? 58  LEU   B N   1 
ATOM   2898 C  CA  . LEU   B 1 61  ? 32.66928  13.40845 -18.10748 1.000 70.72468  ? 58  LEU   B CA  1 
ATOM   2899 C  C   . LEU   B 1 61  ? 33.68119  14.37018 -18.72790 1.000 74.59650  ? 58  LEU   B C   1 
ATOM   2900 O  O   . LEU   B 1 61  ? 34.79159  13.95999 -19.07850 1.000 86.85882  ? 58  LEU   B O   1 
ATOM   2901 C  CB  . LEU   B 1 61  ? 32.98688  13.16072 -16.63229 1.000 73.02840  ? 58  LEU   B CB  1 
ATOM   2902 C  CG  . LEU   B 1 61  ? 32.78425  14.29404 -15.62164 1.000 80.90756  ? 58  LEU   B CG  1 
ATOM   2903 C  CD1 . LEU   B 1 61  ? 32.42225  13.71379 -14.26918 1.000 77.57546  ? 58  LEU   B CD1 1 
ATOM   2904 C  CD2 . LEU   B 1 61  ? 34.02491  15.16620 -15.49853 1.000 87.36798  ? 58  LEU   B CD2 1 
ATOM   2905 N  N   . PRO   B 1 62  ? 33.33063  15.64855 -18.88275 1.000 76.14097  ? 59  PRO   B N   1 
ATOM   2906 C  CA  . PRO   B 1 62  ? 34.24334  16.58886 -19.55344 1.000 77.72415  ? 59  PRO   B CA  1 
ATOM   2907 C  C   . PRO   B 1 62  ? 35.57196  16.76877 -18.83269 1.000 76.52742  ? 59  PRO   B C   1 
ATOM   2908 O  O   . PRO   B 1 62  ? 35.62320  17.32742 -17.73294 1.000 81.51146  ? 59  PRO   B O   1 
ATOM   2909 C  CB  . PRO   B 1 62  ? 33.44279  17.89807 -19.58000 1.000 73.38713  ? 59  PRO   B CB  1 
ATOM   2910 C  CG  . PRO   B 1 62  ? 32.01300  17.47968 -19.42207 1.000 75.43733  ? 59  PRO   B CG  1 
ATOM   2911 C  CD  . PRO   B 1 62  ? 32.04291  16.27374 -18.53882 1.000 67.08528  ? 59  PRO   B CD  1 
ATOM   2912 N  N   . ASN   B 1 63  ? 36.65652  16.29229 -19.44998 1.000 77.79517  ? 60  ASN   B N   1 
ATOM   2913 C  CA  . ASN   B 1 63  ? 37.98782  16.38475 -18.86968 1.000 74.13619  ? 60  ASN   B CA  1 
ATOM   2914 C  C   . ASN   B 1 63  ? 38.88135  17.40860 -19.55748 1.000 78.40391  ? 60  ASN   B C   1 
ATOM   2915 O  O   . ASN   B 1 63  ? 40.00217  17.63456 -19.08945 1.000 96.49245  ? 60  ASN   B O   1 
ATOM   2916 C  CB  . ASN   B 1 63  ? 38.68232  15.01090 -18.88504 1.000 76.32361  ? 60  ASN   B CB  1 
ATOM   2917 C  CG  . ASN   B 1 63  ? 38.71919  14.37835 -20.26741 1.000 84.43885  ? 60  ASN   B CG  1 
ATOM   2918 O  OD1 . ASN   B 1 63  ? 38.84021  15.06167 -21.28496 1.000 86.16632  ? 60  ASN   B OD1 1 
ATOM   2919 N  ND2 . ASN   B 1 63  ? 38.61712  13.05583 -20.30507 1.000 96.61922  ? 60  ASN   B ND2 1 
ATOM   2920 N  N   . ASP   B 1 64  ? 38.43150  18.01960 -20.65152 1.000 68.01884  ? 61  ASP   B N   1 
ATOM   2921 C  CA  . ASP   B 1 64  ? 39.16709  19.08559 -21.31761 1.000 70.76010  ? 61  ASP   B CA  1 
ATOM   2922 C  C   . ASP   B 1 64  ? 38.20165  20.21785 -21.65534 1.000 68.73344  ? 61  ASP   B C   1 
ATOM   2923 O  O   . ASP   B 1 64  ? 36.99334  20.12789 -21.41952 1.000 70.83644  ? 61  ASP   B O   1 
ATOM   2924 C  CB  . ASP   B 1 64  ? 39.89106  18.57644 -22.57326 1.000 73.61342  ? 61  ASP   B CB  1 
ATOM   2925 C  CG  . ASP   B 1 64  ? 38.95273  17.92346 -23.57572 1.000 79.97140  ? 61  ASP   B CG  1 
ATOM   2926 O  OD1 . ASP   B 1 64  ? 37.72409  18.02579 -23.40541 1.000 83.34154  ? 61  ASP   B OD1 1 
ATOM   2927 O  OD2 . ASP   B 1 64  ? 39.44968  17.31157 -24.54797 1.000 88.66531  ? 61  ASP   B OD2 1 
ATOM   2928 N  N   . ASP   B 1 65  ? 38.74199  21.29448 -22.22603 1.000 66.30466  ? 62  ASP   B N   1 
ATOM   2929 C  CA  . ASP   B 1 65  ? 37.93250  22.48761 -22.43925 1.000 67.67274  ? 62  ASP   B CA  1 
ATOM   2930 C  C   . ASP   B 1 65  ? 36.93397  22.30964 -23.57632 1.000 69.84095  ? 62  ASP   B C   1 
ATOM   2931 O  O   . ASP   B 1 65  ? 35.83825  22.88014 -23.52671 1.000 68.24417  ? 62  ASP   B O   1 
ATOM   2932 C  CB  . ASP   B 1 65  ? 38.83089  23.68999 -22.70593 1.000 62.74572  ? 62  ASP   B CB  1 
ATOM   2933 C  CG  . ASP   B 1 65  ? 38.15123  24.99385 -22.38010 1.000 64.74085  ? 62  ASP   B CG  1 
ATOM   2934 O  OD1 . ASP   B 1 65  ? 37.98892  25.29137 -21.17712 1.000 68.23560  ? 62  ASP   B OD1 1 
ATOM   2935 O  OD2 . ASP   B 1 65  ? 37.77422  25.71343 -23.32899 1.000 61.23724  ? 62  ASP   B OD2 1 
ATOM   2936 N  N   . THR   B 1 66  ? 37.28888  21.54270 -24.60970 1.000 66.42453  ? 63  THR   B N   1 
ATOM   2937 C  CA  . THR   B 1 66  ? 36.34880  21.31899 -25.70282 1.000 69.09562  ? 63  THR   B CA  1 
ATOM   2938 C  C   . THR   B 1 66  ? 35.08549  20.62778 -25.20695 1.000 69.84892  ? 63  THR   B C   1 
ATOM   2939 O  O   . THR   B 1 66  ? 33.97043  21.02154 -25.56888 1.000 68.47894  ? 63  THR   B O   1 
ATOM   2940 C  CB  . THR   B 1 66  ? 37.00800  20.49831 -26.81002 1.000 69.16488  ? 63  THR   B CB  1 
ATOM   2941 O  OG1 . THR   B 1 66  ? 38.13693  21.21282 -27.32653 1.000 76.02080  ? 63  THR   B OG1 1 
ATOM   2942 C  CG2 . THR   B 1 66  ? 36.02139  20.24399 -27.93647 1.000 61.73697  ? 63  THR   B CG2 1 
ATOM   2943 N  N   . LEU   B 1 67  ? 35.23931  19.60773 -24.35920 1.000 64.30036  ? 64  LEU   B N   1 
ATOM   2944 C  CA  . LEU   B 1 67  ? 34.07554  18.90473 -23.83310 1.000 65.84358  ? 64  LEU   B CA  1 
ATOM   2945 C  C   . LEU   B 1 67  ? 33.34012  19.72603 -22.78088 1.000 70.08574  ? 64  LEU   B C   1 
ATOM   2946 O  O   . LEU   B 1 67  ? 32.12490  19.57090 -22.62174 1.000 71.74411  ? 64  LEU   B O   1 
ATOM   2947 C  CB  . LEU   B 1 67  ? 34.49031  17.55136 -23.25735 1.000 73.48852  ? 64  LEU   B CB  1 
ATOM   2948 C  CG  . LEU   B 1 67  ? 35.03549  16.53989 -24.26508 1.000 71.10137  ? 64  LEU   B CG  1 
ATOM   2949 C  CD1 . LEU   B 1 67  ? 35.38217  15.23071 -23.57310 1.000 70.52799  ? 64  LEU   B CD1 1 
ATOM   2950 C  CD2 . LEU   B 1 67  ? 34.03547  16.31753 -25.38586 1.000 71.64376  ? 64  LEU   B CD2 1 
ATOM   2951 N  N   . ARG   B 1 68  ? 34.04807  20.58238 -22.04014 1.000 65.63569  ? 65  ARG   B N   1 
ATOM   2952 C  CA  . ARG   B 1 68  ? 33.36296  21.44684 -21.08436 1.000 62.02376  ? 65  ARG   B CA  1 
ATOM   2953 C  C   . ARG   B 1 68  ? 32.45727  22.44126 -21.79828 1.000 61.40201  ? 65  ARG   B C   1 
ATOM   2954 O  O   . ARG   B 1 68  ? 31.31437  22.66060 -21.38020 1.000 66.08880  ? 65  ARG   B O   1 
ATOM   2955 C  CB  . ARG   B 1 68  ? 34.37356  22.17863 -20.20166 1.000 65.47300  ? 65  ARG   B CB  1 
ATOM   2956 C  CG  . ARG   B 1 68  ? 35.00272  21.30841 -19.12459 1.000 67.94090  ? 65  ARG   B CG  1 
ATOM   2957 C  CD  . ARG   B 1 68  ? 35.72310  22.15039 -18.08251 1.000 63.08426  ? 65  ARG   B CD  1 
ATOM   2958 N  NE  . ARG   B 1 68  ? 36.76775  22.97844 -18.67432 1.000 75.76085  ? 65  ARG   B NE  1 
ATOM   2959 C  CZ  . ARG   B 1 68  ? 38.03029  22.60079 -18.82288 1.000 71.83512  ? 65  ARG   B CZ  1 
ATOM   2960 N  NH1 . ARG   B 1 68  ? 38.44330  21.40380 -18.43756 1.000 58.79648  ? 65  ARG   B NH1 1 
ATOM   2961 N  NH2 . ARG   B 1 68  ? 38.89987  23.44531 -19.37241 1.000 67.24233  ? 65  ARG   B NH2 1 
ATOM   2962 N  N   . VAL   B 1 69  ? 32.95195  23.05439 -22.87482 1.000 60.24875  ? 66  VAL   B N   1 
ATOM   2963 C  CA  . VAL   B 1 69  ? 32.13588  23.99156 -23.64227 1.000 60.74417  ? 66  VAL   B CA  1 
ATOM   2964 C  C   . VAL   B 1 69  ? 30.95855  23.26748 -24.28538 1.000 64.18363  ? 66  VAL   B C   1 
ATOM   2965 O  O   . VAL   B 1 69  ? 29.81209  23.72764 -24.21939 1.000 64.85261  ? 66  VAL   B O   1 
ATOM   2966 C  CB  . VAL   B 1 69  ? 32.99772  24.71394 -24.69248 1.000 55.19145  ? 66  VAL   B CB  1 
ATOM   2967 C  CG1 . VAL   B 1 69  ? 32.11942  25.50303 -25.65128 1.000 48.30007  ? 66  VAL   B CG1 1 
ATOM   2968 C  CG2 . VAL   B 1 69  ? 34.01237  25.62159 -24.00884 1.000 50.82971  ? 66  VAL   B CG2 1 
ATOM   2969 N  N   . GLU   B 1 70  ? 31.22535  22.12110 -24.91808 1.000 58.22511  ? 67  GLU   B N   1 
ATOM   2970 C  CA  . GLU   B 1 70  ? 30.15456  21.36247 -25.55785 1.000 62.25257  ? 67  GLU   B CA  1 
ATOM   2971 C  C   . GLU   B 1 70  ? 29.10735  20.91791 -24.54392 1.000 65.02734  ? 67  GLU   B C   1 
ATOM   2972 O  O   . GLU   B 1 70  ? 27.90941  20.88856 -24.85013 1.000 68.91584  ? 67  GLU   B O   1 
ATOM   2973 C  CB  . GLU   B 1 70  ? 30.73435  20.16045 -26.30665 1.000 63.07736  ? 67  GLU   B CB  1 
ATOM   2974 C  CG  . GLU   B 1 70  ? 31.52572  20.53905 -27.55814 1.000 76.73898  ? 67  GLU   B CG  1 
ATOM   2975 C  CD  . GLU   B 1 70  ? 32.19846  19.34799 -28.22082 1.000 90.20051  ? 67  GLU   B CD  1 
ATOM   2976 O  OE1 . GLU   B 1 70  ? 32.17208  18.24625 -27.63156 1.000 84.93752  ? 67  GLU   B OE1 1 
ATOM   2977 O  OE2 . GLU   B 1 70  ? 32.75481  19.51444 -29.33038 1.000 85.77356  ? 67  GLU   B OE2 1 
ATOM   2978 N  N   . ALA   B 1 71  ? 29.53731  20.57523 -23.32748 1.000 67.51584  ? 68  ALA   B N   1 
ATOM   2979 C  CA  . ALA   B 1 71  ? 28.58776  20.13713 -22.30993 1.000 63.24144  ? 68  ALA   B CA  1 
ATOM   2980 C  C   . ALA   B 1 71  ? 27.66487  21.27239 -21.88427 1.000 61.61068  ? 68  ALA   B C   1 
ATOM   2981 O  O   . ALA   B 1 71  ? 26.46034  21.06165 -21.70231 1.000 63.95884  ? 68  ALA   B O   1 
ATOM   2982 C  CB  . ALA   B 1 71  ? 29.32861  19.56811 -21.10114 1.000 57.64673  ? 68  ALA   B CB  1 
ATOM   2983 N  N   . PHE   B 1 72  ? 28.20452  22.48177 -21.71199 1.000 58.54059  ? 69  PHE   B N   1 
ATOM   2984 C  CA  . PHE   B 1 72  ? 27.35160  23.60176 -21.32851 1.000 59.99674  ? 69  PHE   B CA  1 
ATOM   2985 C  C   . PHE   B 1 72  ? 26.39712  23.97573 -22.45304 1.000 59.23226  ? 69  PHE   B C   1 
ATOM   2986 O  O   . PHE   B 1 72  ? 25.20078  24.16934 -22.22369 1.000 57.89566  ? 69  PHE   B O   1 
ATOM   2987 C  CB  . PHE   B 1 72  ? 28.18496  24.81653 -20.92378 1.000 60.70303  ? 69  PHE   B CB  1 
ATOM   2988 C  CG  . PHE   B 1 72  ? 27.36037  26.05613 -20.71642 1.000 58.33449  ? 69  PHE   B CG  1 
ATOM   2989 C  CD1 . PHE   B 1 72  ? 26.73626  26.29450 -19.50460 1.000 54.07754  ? 69  PHE   B CD1 1 
ATOM   2990 C  CD2 . PHE   B 1 72  ? 27.18573  26.97009 -21.74559 1.000 57.57822  ? 69  PHE   B CD2 1 
ATOM   2991 C  CE1 . PHE   B 1 72  ? 25.96388  27.42645 -19.31953 1.000 53.60393  ? 69  PHE   B CE1 1 
ATOM   2992 C  CE2 . PHE   B 1 72  ? 26.41887  28.10462 -21.56707 1.000 54.24617  ? 69  PHE   B CE2 1 
ATOM   2993 C  CZ  . PHE   B 1 72  ? 25.80673  28.33274 -20.35256 1.000 59.64923  ? 69  PHE   B CZ  1 
ATOM   2994 N  N   . GLU   B 1 73  ? 26.90562  24.09065 -23.67888 1.000 63.43928  ? 70  GLU   B N   1 
ATOM   2995 C  CA  . GLU   B 1 73  ? 26.03671  24.48374 -24.77909 1.000 58.42228  ? 70  GLU   B CA  1 
ATOM   2996 C  C   . GLU   B 1 73  ? 24.88099  23.51256 -24.97203 1.000 53.84073  ? 70  GLU   B C   1 
ATOM   2997 O  O   . GLU   B 1 73  ? 23.83170  23.91165 -25.48877 1.000 62.69590  ? 70  GLU   B O   1 
ATOM   2998 C  CB  . GLU   B 1 73  ? 26.84651  24.61943 -26.06706 1.000 42.81025  ? 70  GLU   B CB  1 
ATOM   2999 C  CG  . GLU   B 1 73  ? 27.54747  25.96035 -26.18446 1.000 54.65455  ? 70  GLU   B CG  1 
ATOM   3000 C  CD  . GLU   B 1 73  ? 28.65874  25.96287 -27.20905 1.000 87.34829  ? 70  GLU   B CD  1 
ATOM   3001 O  OE1 . GLU   B 1 73  ? 28.77326  24.98492 -27.98071 1.000 87.84020  ? 70  GLU   B OE1 1 
ATOM   3002 O  OE2 . GLU   B 1 73  ? 29.42332  26.95038 -27.23771 1.000 96.87691  ? 70  GLU   B OE2 1 
ATOM   3003 N  N   . TYR   B 1 74  ? 25.03117  22.25864 -24.53954 1.000 54.64561  ? 71  TYR   B N   1 
ATOM   3004 C  CA  . TYR   B 1 74  ? 23.95044  21.29100 -24.67570 1.000 57.95172  ? 71  TYR   B CA  1 
ATOM   3005 C  C   . TYR   B 1 74  ? 23.07015  21.22529 -23.43330 1.000 59.05609  ? 71  TYR   B C   1 
ATOM   3006 O  O   . TYR   B 1 74  ? 21.84396  21.15149 -23.55283 1.000 65.76779  ? 71  TYR   B O   1 
ATOM   3007 C  CB  . TYR   B 1 74  ? 24.51430  19.90439 -24.98843 1.000 56.47948  ? 71  TYR   B CB  1 
ATOM   3008 C  CG  . TYR   B 1 74  ? 23.49389  18.97765 -25.61105 1.000 65.98090  ? 71  TYR   B CG  1 
ATOM   3009 C  CD1 . TYR   B 1 74  ? 22.82901  19.34088 -26.77433 1.000 65.85679  ? 71  TYR   B CD1 1 
ATOM   3010 C  CD2 . TYR   B 1 74  ? 23.20110  17.74141 -25.04926 1.000 70.14171  ? 71  TYR   B CD2 1 
ATOM   3011 C  CE1 . TYR   B 1 74  ? 21.89706  18.50773 -27.35901 1.000 66.02545  ? 71  TYR   B CE1 1 
ATOM   3012 C  CE2 . TYR   B 1 74  ? 22.26942  16.89617 -25.63080 1.000 68.12614  ? 71  TYR   B CE2 1 
ATOM   3013 C  CZ  . TYR   B 1 74  ? 21.62025  17.28723 -26.78639 1.000 69.47837  ? 71  TYR   B CZ  1 
ATOM   3014 O  OH  . TYR   B 1 74  ? 20.69010  16.46100 -27.37687 1.000 68.53366  ? 71  TYR   B OH  1 
ATOM   3015 N  N   . TYR   B 1 75  ? 23.66761  21.24722 -22.23963 1.000 59.10450  ? 72  TYR   B N   1 
ATOM   3016 C  CA  . TYR   B 1 75  ? 22.92570  21.09037 -20.99507 1.000 54.47424  ? 72  TYR   B CA  1 
ATOM   3017 C  C   . TYR   B 1 75  ? 22.75977  22.38303 -20.20706 1.000 56.35890  ? 72  TYR   B C   1 
ATOM   3018 O  O   . TYR   B 1 75  ? 21.96905  22.40553 -19.25635 1.000 52.68981  ? 72  TYR   B O   1 
ATOM   3019 C  CB  . TYR   B 1 75  ? 23.60606  20.04875 -20.09155 1.000 59.57042  ? 72  TYR   B CB  1 
ATOM   3020 C  CG  . TYR   B 1 75  ? 23.82876  18.70022 -20.73996 1.000 59.45596  ? 72  TYR   B CG  1 
ATOM   3021 C  CD1 . TYR   B 1 75  ? 22.78299  17.79929 -20.88964 1.000 59.66678  ? 72  TYR   B CD1 1 
ATOM   3022 C  CD2 . TYR   B 1 75  ? 25.08740  18.32258 -21.19011 1.000 53.65258  ? 72  TYR   B CD2 1 
ATOM   3023 C  CE1 . TYR   B 1 75  ? 22.98201  16.56398 -21.47961 1.000 61.32767  ? 72  TYR   B CE1 1 
ATOM   3024 C  CE2 . TYR   B 1 75  ? 25.29598  17.08967 -21.78088 1.000 57.22319  ? 72  TYR   B CE2 1 
ATOM   3025 C  CZ  . TYR   B 1 75  ? 24.23940  16.21430 -21.92223 1.000 61.41918  ? 72  TYR   B CZ  1 
ATOM   3026 O  OH  . TYR   B 1 75  ? 24.43587  14.98499 -22.50750 1.000 67.48619  ? 72  TYR   B OH  1 
ATOM   3027 N  N   . HIS   B 1 76  ? 23.49734  23.44100 -20.55223 1.000 56.10085  ? 73  HIS   B N   1 
ATOM   3028 C  CA  . HIS   B 1 76  ? 23.43252  24.72675 -19.84868 1.000 55.39228  ? 73  HIS   B CA  1 
ATOM   3029 C  C   . HIS   B 1 76  ? 23.76130  24.57186 -18.36600 1.000 57.04544  ? 73  HIS   B C   1 
ATOM   3030 O  O   . HIS   B 1 76  ? 23.18940  25.24598 -17.50772 1.000 64.94789  ? 73  HIS   B O   1 
ATOM   3031 C  CB  . HIS   B 1 76  ? 22.07618  25.40800 -20.05411 1.000 53.58544  ? 73  HIS   B CB  1 
ATOM   3032 C  CG  . HIS   B 1 76  ? 21.89455  25.97386 -21.42952 1.000 57.56088  ? 73  HIS   B CG  1 
ATOM   3033 N  ND1 . HIS   B 1 76  ? 21.09143  27.06286 -21.68775 1.000 53.98100  ? 73  HIS   B ND1 1 
ATOM   3034 C  CD2 . HIS   B 1 76  ? 22.42838  25.61122 -22.62037 1.000 53.75211  ? 73  HIS   B CD2 1 
ATOM   3035 C  CE1 . HIS   B 1 76  ? 21.13142  27.34230 -22.97735 1.000 51.35398  ? 73  HIS   B CE1 1 
ATOM   3036 N  NE2 . HIS   B 1 76  ? 21.93583  26.47608 -23.56661 1.000 58.77452  ? 73  HIS   B NE2 1 
ATOM   3037 N  N   . THR   B 1 77  ? 24.70062  23.67843 -18.06409 1.000 59.07753  ? 74  THR   B N   1 
ATOM   3038 C  CA  . THR   B 1 77  ? 25.20784  23.52935 -16.70935 1.000 64.80308  ? 74  THR   B CA  1 
ATOM   3039 C  C   . THR   B 1 77  ? 26.68180  23.15902 -16.76570 1.000 62.64468  ? 74  THR   B C   1 
ATOM   3040 O  O   . THR   B 1 77  ? 27.13363  22.48718 -17.69623 1.000 62.28974  ? 74  THR   B O   1 
ATOM   3041 C  CB  . THR   B 1 77  ? 24.43197  22.47221 -15.91057 1.000 66.46772  ? 74  THR   B CB  1 
ATOM   3042 O  OG1 . THR   B 1 77  ? 24.90970  22.44785 -14.55887 1.000 66.35631  ? 74  THR   B OG1 1 
ATOM   3043 C  CG2 . THR   B 1 77  ? 24.60922  21.09030 -16.52841 1.000 63.44844  ? 74  THR   B CG2 1 
ATOM   3044 N  N   . THR   B 1 78  ? 27.42997  23.62719 -15.76882 1.000 62.93052  ? 75  THR   B N   1 
ATOM   3045 C  CA  . THR   B 1 78  ? 28.82245  23.24452 -15.58793 1.000 60.46183  ? 75  THR   B CA  1 
ATOM   3046 C  C   . THR   B 1 78  ? 29.02224  22.30539 -14.40562 1.000 65.32789  ? 75  THR   B C   1 
ATOM   3047 O  O   . THR   B 1 78  ? 30.16479  21.93517 -14.11539 1.000 62.63126  ? 75  THR   B O   1 
ATOM   3048 C  CB  . THR   B 1 78  ? 29.70482  24.48827 -15.41572 1.000 54.67892  ? 75  THR   B CB  1 
ATOM   3049 O  OG1 . THR   B 1 78  ? 29.14267  25.34391 -14.41313 1.000 67.55364  ? 75  THR   B OG1 1 
ATOM   3050 C  CG2 . THR   B 1 78  ? 29.81309  25.25100 -16.72138 1.000 57.95985  ? 75  THR   B CG2 1 
ATOM   3051 N  N   . ASP   B 1 79  ? 27.94861  21.91218 -13.72396 1.000 65.13226  ? 76  ASP   B N   1 
ATOM   3052 C  CA  . ASP   B 1 79  ? 28.03096  20.97802 -12.60639 1.000 63.18091  ? 76  ASP   B CA  1 
ATOM   3053 C  C   . ASP   B 1 79  ? 28.67307  19.66781 -13.04791 1.000 70.10598  ? 76  ASP   B C   1 
ATOM   3054 O  O   . ASP   B 1 79  ? 28.13307  18.98964 -13.93493 1.000 72.96435  ? 76  ASP   B O   1 
ATOM   3055 C  CB  . ASP   B 1 79  ? 26.64423  20.70912 -12.03100 1.000 72.81118  ? 76  ASP   B CB  1 
ATOM   3056 C  CG  . ASP   B 1 79  ? 26.65094  19.60725 -10.99097 1.000 79.34552  ? 76  ASP   B CG  1 
ATOM   3057 O  OD1 . ASP   B 1 79  ? 27.29249  19.78988 -9.93677  1.000 81.94461  ? 76  ASP   B OD1 1 
ATOM   3058 O  OD2 . ASP   B 1 79  ? 26.01939  18.55651 -11.22878 1.000 88.84224  ? 76  ASP   B OD2 1 
ATOM   3059 N  N   . PRO   B 1 80  ? 29.80785  19.27394 -12.46452 1.000 80.56414  ? 77  PRO   B N   1 
ATOM   3060 C  CA  . PRO   B 1 80  ? 30.50054  18.06862 -12.94871 1.000 74.25808  ? 77  PRO   B CA  1 
ATOM   3061 C  C   . PRO   B 1 80  ? 29.69952  16.79135 -12.77456 1.000 76.42258  ? 77  PRO   B C   1 
ATOM   3062 O  O   . PRO   B 1 80  ? 29.92378  15.82603 -13.51587 1.000 75.60906  ? 77  PRO   B O   1 
ATOM   3063 C  CB  . PRO   B 1 80  ? 31.78587  18.04351 -12.10836 1.000 62.07994  ? 77  PRO   B CB  1 
ATOM   3064 C  CG  . PRO   B 1 80  ? 31.93124  19.43578 -11.56691 1.000 61.96508  ? 77  PRO   B CG  1 
ATOM   3065 C  CD  . PRO   B 1 80  ? 30.53687  19.92920 -11.36717 1.000 69.37034  ? 77  PRO   B CD  1 
ATOM   3066 N  N   . SER   B 1 81  ? 28.77849  16.75125 -11.81349 1.000 66.51906  ? 78  SER   B N   1 
ATOM   3067 C  CA  . SER   B 1 81  ? 28.02591  15.54177 -11.51263 1.000 74.61131  ? 78  SER   B CA  1 
ATOM   3068 C  C   . SER   B 1 81  ? 26.79214  15.35387 -12.38568 1.000 82.81036  ? 78  SER   B C   1 
ATOM   3069 O  O   . SER   B 1 81  ? 26.15459  14.29929 -12.29660 1.000 86.06949  ? 78  SER   B O   1 
ATOM   3070 C  CB  . SER   B 1 81  ? 27.59548  15.54281 -10.04394 1.000 78.05894  ? 78  SER   B CB  1 
ATOM   3071 O  OG  . SER   B 1 81  ? 26.63896  16.55865 -9.80618  1.000 79.39656  ? 78  SER   B OG  1 
ATOM   3072 N  N   . PHE   B 1 82  ? 26.43101  16.34449 -13.20722 1.000 78.34574  ? 79  PHE   B N   1 
ATOM   3073 C  CA  . PHE   B 1 82  ? 25.18352  16.26405 -13.96288 1.000 71.66899  ? 79  PHE   B CA  1 
ATOM   3074 C  C   . PHE   B 1 82  ? 25.14831  15.01887 -14.84181 1.000 69.16684  ? 79  PHE   B C   1 
ATOM   3075 O  O   . PHE   B 1 82  ? 24.16752  14.26510 -14.82840 1.000 71.69194  ? 79  PHE   B O   1 
ATOM   3076 C  CB  . PHE   B 1 82  ? 24.98545  17.52626 -14.80424 1.000 64.97893  ? 79  PHE   B CB  1 
ATOM   3077 C  CG  . PHE   B 1 82  ? 23.66371  17.56939 -15.51926 1.000 65.35845  ? 79  PHE   B CG  1 
ATOM   3078 C  CD1 . PHE   B 1 82  ? 22.53830  18.07062 -14.88706 1.000 65.95611  ? 79  PHE   B CD1 1 
ATOM   3079 C  CD2 . PHE   B 1 82  ? 23.54213  17.09656 -16.81735 1.000 66.41924  ? 79  PHE   B CD2 1 
ATOM   3080 C  CE1 . PHE   B 1 82  ? 21.31797  18.10533 -15.53491 1.000 67.68679  ? 79  PHE   B CE1 1 
ATOM   3081 C  CE2 . PHE   B 1 82  ? 22.32629  17.12650 -17.46943 1.000 62.26911  ? 79  PHE   B CE2 1 
ATOM   3082 C  CZ  . PHE   B 1 82  ? 21.21250  17.63175 -16.82743 1.000 67.26719  ? 79  PHE   B CZ  1 
ATOM   3083 N  N   . LEU   B 1 83  ? 26.20920  14.78975 -15.61771 1.000 68.56437  ? 80  LEU   B N   1 
ATOM   3084 C  CA  . LEU   B 1 83  ? 26.22851  13.63844 -16.51583 1.000 73.17998  ? 80  LEU   B CA  1 
ATOM   3085 C  C   . LEU   B 1 83  ? 26.03703  12.33205 -15.75441 1.000 75.55447  ? 80  LEU   B C   1 
ATOM   3086 O  O   . LEU   B 1 83  ? 25.35532  11.41933 -16.23492 1.000 79.21384  ? 80  LEU   B O   1 
ATOM   3087 C  CB  . LEU   B 1 83  ? 27.53378  13.61239 -17.30997 1.000 72.14622  ? 80  LEU   B CB  1 
ATOM   3088 C  CG  . LEU   B 1 83  ? 27.58706  12.61736 -18.46848 1.000 77.55775  ? 80  LEU   B CG  1 
ATOM   3089 C  CD1 . LEU   B 1 83  ? 26.34272  12.73410 -19.32847 1.000 78.83864  ? 80  LEU   B CD1 1 
ATOM   3090 C  CD2 . LEU   B 1 83  ? 28.83245  12.84777 -19.30212 1.000 82.91289  ? 80  LEU   B CD2 1 
ATOM   3091 N  N   . GLY   B 1 84  ? 26.62767  12.22404 -14.56537 1.000 71.80701  ? 81  GLY   B N   1 
ATOM   3092 C  CA  . GLY   B 1 84  ? 26.47955  11.00282 -13.79059 1.000 71.32945  ? 81  GLY   B CA  1 
ATOM   3093 C  C   . GLY   B 1 84  ? 25.05167  10.77223 -13.33294 1.000 73.63122  ? 81  GLY   B C   1 
ATOM   3094 O  O   . GLY   B 1 84  ? 24.50854  9.67394  -13.48569 1.000 71.83369  ? 81  GLY   B O   1 
ATOM   3095 N  N   . ARG   B 1 85  ? 24.42272  11.80633 -12.76653 1.000 70.33515  ? 82  ARG   B N   1 
ATOM   3096 C  CA  . ARG   B 1 85  ? 23.02792  11.68517 -12.35251 1.000 65.93763  ? 82  ARG   B CA  1 
ATOM   3097 C  C   . ARG   B 1 85  ? 22.12338  11.42333 -13.54990 1.000 76.35895  ? 82  ARG   B C   1 
ATOM   3098 O  O   . ARG   B 1 85  ? 21.15587  10.65851 -13.45372 1.000 80.99226  ? 82  ARG   B O   1 
ATOM   3099 C  CB  . ARG   B 1 85  ? 22.58787  12.95241 -11.61799 1.000 68.41752  ? 82  ARG   B CB  1 
ATOM   3100 C  CG  . ARG   B 1 85  ? 23.60400  13.46341 -10.61209 1.000 72.01056  ? 82  ARG   B CG  1 
ATOM   3101 C  CD  . ARG   B 1 85  ? 22.98666  14.43531 -9.62111  1.000 68.11329  ? 82  ARG   B CD  1 
ATOM   3102 N  NE  . ARG   B 1 85  ? 22.23610  15.50487 -10.26764 1.000 74.97087  ? 82  ARG   B NE  1 
ATOM   3103 C  CZ  . ARG   B 1 85  ? 22.74908  16.67845 -10.61111 1.000 81.80225  ? 82  ARG   B CZ  1 
ATOM   3104 N  NH1 . ARG   B 1 85  ? 24.02767  16.95727 -10.41740 1.000 86.06344  ? 82  ARG   B NH1 1 
ATOM   3105 N  NH2 . ARG   B 1 85  ? 21.95755  17.59886 -11.15517 1.000 80.78418  ? 82  ARG   B NH2 1 
ATOM   3106 N  N   . TYR   B 1 86  ? 22.42748  12.05258 -14.68696 1.000 72.21668  ? 83  TYR   B N   1 
ATOM   3107 C  CA  . TYR   B 1 86  ? 21.68090  11.80301 -15.91579 1.000 67.92108  ? 83  TYR   B CA  1 
ATOM   3108 C  C   . TYR   B 1 86  ? 21.83784  10.35449 -16.36874 1.000 70.13072  ? 83  TYR   B C   1 
ATOM   3109 O  O   . TYR   B 1 86  ? 20.84502  9.65856  -16.61199 1.000 72.66590  ? 83  TYR   B O   1 
ATOM   3110 C  CB  . TYR   B 1 86  ? 22.14339  12.78799 -16.99719 1.000 68.14086  ? 83  TYR   B CB  1 
ATOM   3111 C  CG  . TYR   B 1 86  ? 21.57139  12.57881 -18.38699 1.000 67.50657  ? 83  TYR   B CG  1 
ATOM   3112 C  CD1 . TYR   B 1 86  ? 20.28638  12.08324 -18.57553 1.000 73.93981  ? 83  TYR   B CD1 1 
ATOM   3113 C  CD2 . TYR   B 1 86  ? 22.32069  12.89193 -19.51425 1.000 72.73073  ? 83  TYR   B CD2 1 
ATOM   3114 C  CE1 . TYR   B 1 86  ? 19.77115  11.89394 -19.84897 1.000 71.14403  ? 83  TYR   B CE1 1 
ATOM   3115 C  CE2 . TYR   B 1 86  ? 21.81357  12.70837 -20.78924 1.000 69.17973  ? 83  TYR   B CE2 1 
ATOM   3116 C  CZ  . TYR   B 1 86  ? 20.53958  12.20874 -20.95010 1.000 70.94471  ? 83  TYR   B CZ  1 
ATOM   3117 O  OH  . TYR   B 1 86  ? 20.03346  12.02523 -22.21651 1.000 73.38012  ? 83  TYR   B OH  1 
ATOM   3118 N  N   . MET   B 1 87  ? 23.08131  9.88136  -16.48502 1.000 73.09864  ? 84  MET   B N   1 
ATOM   3119 C  CA  . MET   B 1 87  ? 23.31271  8.51232  -16.94111 1.000 73.51271  ? 84  MET   B CA  1 
ATOM   3120 C  C   . MET   B 1 87  ? 22.75665  7.49080  -15.95446 1.000 72.62435  ? 84  MET   B C   1 
ATOM   3121 O  O   . MET   B 1 87  ? 22.26233  6.43240  -16.36134 1.000 72.81517  ? 84  MET   B O   1 
ATOM   3122 C  CB  . MET   B 1 87  ? 24.80582  8.27858  -17.17036 1.000 73.23818  ? 84  MET   B CB  1 
ATOM   3123 C  CG  . MET   B 1 87  ? 25.38750  9.03753  -18.35548 1.000 74.32999  ? 84  MET   B CG  1 
ATOM   3124 S  SD  . MET   B 1 87  ? 24.82489  8.44416  -19.96198 1.000 86.91489  ? 84  MET   B SD  1 
ATOM   3125 C  CE  . MET   B 1 87  ? 23.71748  9.76710  -20.42906 1.000 78.72935  ? 84  MET   B CE  1 
ATOM   3126 N  N   . SER   B 1 88  ? 22.84000  7.77983  -14.65287 1.000 68.56230  ? 85  SER   B N   1 
ATOM   3127 C  CA  A SER   B 1 88  ? 22.28855  6.86016  -13.66239 0.731 75.36052  ? 85  SER   B CA  1 
ATOM   3128 C  CA  B SER   B 1 88  ? 22.28789  6.86147  -13.66134 0.269 75.43136  ? 85  SER   B CA  1 
ATOM   3129 C  C   . SER   B 1 88  ? 20.77277  6.76934  -13.78269 1.000 74.70546  ? 85  SER   B C   1 
ATOM   3130 O  O   . SER   B 1 88  ? 20.20175  5.67497  -13.69923 1.000 70.28945  ? 85  SER   B O   1 
ATOM   3131 C  CB  A SER   B 1 88  ? 22.69200  7.29335  -12.25103 0.731 73.15183  ? 85  SER   B CB  1 
ATOM   3132 C  CB  B SER   B 1 88  ? 22.68564  7.30091  -12.25217 0.269 73.58868  ? 85  SER   B CB  1 
ATOM   3133 O  OG  A SER   B 1 88  ? 24.08994  7.16227  -12.04819 0.731 70.72286  ? 85  SER   B OG  1 
ATOM   3134 O  OG  B SER   B 1 88  ? 22.08175  8.53770  -11.91455 0.269 72.59608  ? 85  SER   B OG  1 
ATOM   3135 N  N   . ALA   B 1 89  ? 20.10533  7.90829  -13.97792 1.000 74.47748  ? 86  ALA   B N   1 
ATOM   3136 C  CA  . ALA   B 1 89  ? 18.66308  7.88730  -14.18607 1.000 70.88605  ? 86  ALA   B CA  1 
ATOM   3137 C  C   . ALA   B 1 89  ? 18.31650  7.26018  -15.52917 1.000 66.71964  ? 86  ALA   B C   1 
ATOM   3138 O  O   . ALA   B 1 89  ? 17.34356  6.50464  -15.63566 1.000 71.64794  ? 86  ALA   B O   1 
ATOM   3139 C  CB  . ALA   B 1 89  ? 18.09861  9.30457  -14.09040 1.000 64.37089  ? 86  ALA   B CB  1 
ATOM   3140 N  N   . LEU   B 1 90  ? 19.11377  7.54915  -16.56129 1.000 66.80832  ? 87  LEU   B N   1 
ATOM   3141 C  CA  . LEU   B 1 90  ? 18.85641  6.98581  -17.88205 1.000 69.96266  ? 87  LEU   B CA  1 
ATOM   3142 C  C   . LEU   B 1 90  ? 18.95990  5.46656  -17.87198 1.000 70.49404  ? 87  LEU   B C   1 
ATOM   3143 O  O   . LEU   B 1 90  ? 18.26080  4.79164  -18.63587 1.000 70.79934  ? 87  LEU   B O   1 
ATOM   3144 C  CB  . LEU   B 1 90  ? 19.82424  7.58685  -18.90308 1.000 65.92202  ? 87  LEU   B CB  1 
ATOM   3145 C  CG  . LEU   B 1 90  ? 19.74075  7.07568  -20.34138 1.000 64.23010  ? 87  LEU   B CG  1 
ATOM   3146 C  CD1 . LEU   B 1 90  ? 18.32356  7.20640  -20.86999 1.000 62.13749  ? 87  LEU   B CD1 1 
ATOM   3147 C  CD2 . LEU   B 1 90  ? 20.71004  7.83177  -21.22793 1.000 61.73220  ? 87  LEU   B CD2 1 
ATOM   3148 N  N   . ASN   B 1 91  ? 19.82080  4.90983  -17.01720 1.000 82.98626  ? 88  ASN   B N   1 
ATOM   3149 C  CA  . ASN   B 1 91  ? 19.95122  3.45957  -16.93942 1.000 89.50209  ? 88  ASN   B CA  1 
ATOM   3150 C  C   . ASN   B 1 91  ? 18.65105  2.78765  -16.51119 1.000 84.82381  ? 88  ASN   B C   1 
ATOM   3151 O  O   . ASN   B 1 91  ? 18.44397  1.61062  -16.82493 1.000 85.74626  ? 88  ASN   B O   1 
ATOM   3152 C  CB  . ASN   B 1 91  ? 21.08522  3.08352  -15.98405 1.000 84.30579  ? 88  ASN   B CB  1 
ATOM   3153 C  CG  . ASN   B 1 91  ? 21.63573  1.69714  -16.25419 1.000 93.75908  ? 88  ASN   B CG  1 
ATOM   3154 O  OD1 . ASN   B 1 91  ? 21.94017  1.34892  -17.39709 1.000 91.78001  ? 88  ASN   B OD1 1 
ATOM   3155 N  ND2 . ASN   B 1 91  ? 21.76900  0.89790  -15.20254 1.000 90.70286  ? 88  ASN   B ND2 1 
ATOM   3156 N  N   . HIS   B 1 92  ? 17.77393  3.50594  -15.80599 1.000 77.69128  ? 89  HIS   B N   1 
ATOM   3157 C  CA  . HIS   B 1 92  ? 16.46488  2.98574  -15.42430 1.000 79.73639  ? 89  HIS   B CA  1 
ATOM   3158 C  C   . HIS   B 1 92  ? 15.37126  3.37577  -16.41616 1.000 83.12987  ? 89  HIS   B C   1 
ATOM   3159 O  O   . HIS   B 1 92  ? 14.56648  2.52831  -16.81784 1.000 80.35903  ? 89  HIS   B O   1 
ATOM   3160 C  CB  . HIS   B 1 92  ? 16.07664  3.47688  -14.02358 1.000 77.67228  ? 89  HIS   B CB  1 
ATOM   3161 C  CG  . HIS   B 1 92  ? 16.91593  2.91157  -12.92028 1.000 87.60127  ? 89  HIS   B CG  1 
ATOM   3162 N  ND1 . HIS   B 1 92  ? 16.79615  1.60644  -12.49158 1.000 93.67361  ? 89  HIS   B ND1 1 
ATOM   3163 C  CD2 . HIS   B 1 92  ? 17.86916  3.47736  -12.14174 1.000 88.28698  ? 89  HIS   B CD2 1 
ATOM   3164 C  CE1 . HIS   B 1 92  ? 17.64814  1.38968  -11.50518 1.000 91.99809  ? 89  HIS   B CE1 1 
ATOM   3165 N  NE2 . HIS   B 1 92  ? 18.31119  2.50876  -11.27316 1.000 91.74357  ? 89  HIS   B NE2 1 
ATOM   3166 N  N   . THR   B 1 93  ? 15.33277  4.64923  -16.82488 1.000 77.64570  ? 90  THR   B N   1 
ATOM   3167 C  CA  . THR   B 1 93  ? 14.24332  5.12064  -17.67561 1.000 67.19261  ? 90  THR   B CA  1 
ATOM   3168 C  C   . THR   B 1 93  ? 14.27433  4.47808  -19.05707 1.000 69.91251  ? 90  THR   B C   1 
ATOM   3169 O  O   . THR   B 1 93  ? 13.22944  4.37326  -19.70919 1.000 70.79879  ? 90  THR   B O   1 
ATOM   3170 C  CB  . THR   B 1 93  ? 14.28054  6.64606  -17.79494 1.000 60.01834  ? 90  THR   B CB  1 
ATOM   3171 O  OG1 . THR   B 1 93  ? 15.51257  7.05684  -18.39739 1.000 63.49219  ? 90  THR   B OG1 1 
ATOM   3172 C  CG2 . THR   B 1 93  ? 14.15257  7.28947  -16.42771 1.000 55.02086  ? 90  THR   B CG2 1 
ATOM   3173 N  N   . LYS   B 1 94  ? 15.44596  4.04260  -19.52340 1.000 74.88974  ? 91  LYS   B N   1 
ATOM   3174 C  CA  . LYS   B 1 94  ? 15.49543  3.31603  -20.78706 1.000 71.15407  ? 91  LYS   B CA  1 
ATOM   3175 C  C   . LYS   B 1 94  ? 14.82166  1.95372  -20.69734 1.000 71.57097  ? 91  LYS   B C   1 
ATOM   3176 O  O   . LYS   B 1 94  ? 14.55243  1.34502  -21.73761 1.000 75.14430  ? 91  LYS   B O   1 
ATOM   3177 C  CB  . LYS   B 1 94  ? 16.94386  3.13725  -21.24718 1.000 68.84596  ? 91  LYS   B CB  1 
ATOM   3178 C  CG  . LYS   B 1 94  ? 17.71834  2.11595  -20.42724 1.000 87.49945  ? 91  LYS   B CG  1 
ATOM   3179 C  CD  . LYS   B 1 94  ? 19.14524  1.94242  -20.92362 1.000 89.69408  ? 91  LYS   B CD  1 
ATOM   3180 C  CE  . LYS   B 1 94  ? 19.92442  0.99678  -20.02018 1.000 89.01828  ? 91  LYS   B CE  1 
ATOM   3181 N  NZ  . LYS   B 1 94  ? 21.32376  0.80870  -20.48954 1.000 94.32779  ? 91  LYS   B NZ  1 
ATOM   3182 N  N   . LYS   B 1 95  ? 14.55388  1.46296  -19.48666 1.000 80.64616  ? 92  LYS   B N   1 
ATOM   3183 C  CA  . LYS   B 1 95  ? 13.84813  0.20760  -19.27669 1.000 79.42860  ? 92  LYS   B CA  1 
ATOM   3184 C  C   . LYS   B 1 95  ? 12.36147  0.39959  -19.01470 1.000 81.00807  ? 92  LYS   B C   1 
ATOM   3185 O  O   . LYS   B 1 95  ? 11.62643  -0.59186 -18.94910 1.000 84.69746  ? 92  LYS   B O   1 
ATOM   3186 C  CB  . LYS   B 1 95  ? 14.47587  -0.56502 -18.10984 1.000 74.11340  ? 92  LYS   B CB  1 
ATOM   3187 C  CG  . LYS   B 1 95  ? 15.91100  -0.99720 -18.36651 1.000 88.77913  ? 92  LYS   B CG  1 
ATOM   3188 C  CD  . LYS   B 1 95  ? 16.52443  -1.67235 -17.14893 1.000 95.26002  ? 92  LYS   B CD  1 
ATOM   3189 C  CE  . LYS   B 1 95  ? 17.99180  -2.00859 -17.38535 1.000 100.84649 ? 92  LYS   B CE  1 
ATOM   3190 N  NZ  . LYS   B 1 95  ? 18.18753  -2.80576 -18.63101 1.000 106.91831 ? 92  LYS   B NZ  1 
ATOM   3191 N  N   . TRP   B 1 96  ? 11.90582  1.63933  -18.85676 1.000 78.33088  ? 93  TRP   B N   1 
ATOM   3192 C  CA  . TRP   B 1 96  ? 10.49047  1.89911  -18.65549 1.000 68.82859  ? 93  TRP   B CA  1 
ATOM   3193 C  C   . TRP   B 1 96  ? 9.71582   1.71447  -19.95685 1.000 78.70100  ? 93  TRP   B C   1 
ATOM   3194 O  O   . TRP   B 1 96  ? 10.27747  1.70392  -21.05714 1.000 72.34212  ? 93  TRP   B O   1 
ATOM   3195 C  CB  . TRP   B 1 96  ? 10.26810  3.31401  -18.12149 1.000 70.32731  ? 93  TRP   B CB  1 
ATOM   3196 C  CG  . TRP   B 1 96  ? 10.78483  3.53516  -16.73129 1.000 76.87301  ? 93  TRP   B CG  1 
ATOM   3197 C  CD1 . TRP   B 1 96  ? 11.30897  2.59630  -15.89185 1.000 73.59085  ? 93  TRP   B CD1 1 
ATOM   3198 C  CD2 . TRP   B 1 96  ? 10.80437  4.77406  -16.00908 1.000 68.95267  ? 93  TRP   B CD2 1 
ATOM   3199 N  NE1 . TRP   B 1 96  ? 11.66492  3.17467  -14.69846 1.000 67.53236  ? 93  TRP   B NE1 1 
ATOM   3200 C  CE2 . TRP   B 1 96  ? 11.36395  4.51025  -14.74382 1.000 69.58811  ? 93  TRP   B CE2 1 
ATOM   3201 C  CE3 . TRP   B 1 96  ? 10.40761  6.08037  -16.31177 1.000 68.72157  ? 93  TRP   B CE3 1 
ATOM   3202 C  CZ2 . TRP   B 1 96  ? 11.53695  5.50477  -13.78084 1.000 72.30074  ? 93  TRP   B CZ2 1 
ATOM   3203 C  CZ3 . TRP   B 1 96  ? 10.57944  7.06681  -15.35381 1.000 72.60420  ? 93  TRP   B CZ3 1 
ATOM   3204 C  CH2 . TRP   B 1 96  ? 11.13944  6.77345  -14.10442 1.000 71.21352  ? 93  TRP   B CH2 1 
ATOM   3205 N  N   . LYS   B 1 97  ? 8.40316   1.56347  -19.81385 1.000 82.96995  ? 94  LYS   B N   1 
ATOM   3206 C  CA  . LYS   B 1 97  ? 7.49413   1.46968  -20.94702 1.000 72.74061  ? 94  LYS   B CA  1 
ATOM   3207 C  C   . LYS   B 1 97  ? 6.74189   2.78678  -21.08165 1.000 70.47018  ? 94  LYS   B C   1 
ATOM   3208 O  O   . LYS   B 1 97  ? 6.25330   3.33092  -20.08522 1.000 68.99869  ? 94  LYS   B O   1 
ATOM   3209 C  CB  . LYS   B 1 97  ? 6.50831   0.31733  -20.75916 1.000 75.28959  ? 94  LYS   B CB  1 
ATOM   3210 C  CG  . LYS   B 1 97  ? 7.07657   -1.05909 -21.07462 1.000 80.13394  ? 94  LYS   B CG  1 
ATOM   3211 C  CD  . LYS   B 1 97  ? 8.02464   -1.04695 -22.25961 1.000 71.92317  ? 94  LYS   B CD  1 
ATOM   3212 C  CE  . LYS   B 1 97  ? 8.70031   -2.40415 -22.41572 1.000 91.41181  ? 94  LYS   B CE  1 
ATOM   3213 N  NZ  . LYS   B 1 97  ? 9.65453   -2.44011 -23.55992 1.000 92.81954  ? 94  LYS   B NZ  1 
ATOM   3214 N  N   . TYR   B 1 98  ? 6.64192   3.29187  -22.31357 1.000 75.69663  ? 95  TYR   B N   1 
ATOM   3215 C  CA  . TYR   B 1 98  ? 6.04073   4.59490  -22.59469 1.000 73.41139  ? 95  TYR   B CA  1 
ATOM   3216 C  C   . TYR   B 1 98  ? 4.86622   4.42587  -23.55273 1.000 72.48759  ? 95  TYR   B C   1 
ATOM   3217 O  O   . TYR   B 1 98  ? 4.97589   4.73269  -24.74965 1.000 72.17920  ? 95  TYR   B O   1 
ATOM   3218 C  CB  . TYR   B 1 98  ? 7.07933   5.56505  -23.15500 1.000 66.46155  ? 95  TYR   B CB  1 
ATOM   3219 C  CG  . TYR   B 1 98  ? 8.23217   5.80984  -22.21254 1.000 65.61055  ? 95  TYR   B CG  1 
ATOM   3220 C  CD1 . TYR   B 1 98  ? 8.10620   6.69807  -21.15312 1.000 69.65841  ? 95  TYR   B CD1 1 
ATOM   3221 C  CD2 . TYR   B 1 98  ? 9.44425   5.15490  -22.37998 1.000 65.18767  ? 95  TYR   B CD2 1 
ATOM   3222 C  CE1 . TYR   B 1 98  ? 9.15329   6.92885  -20.28691 1.000 73.64395  ? 95  TYR   B CE1 1 
ATOM   3223 C  CE2 . TYR   B 1 98  ? 10.50029  5.37937  -21.51829 1.000 68.00989  ? 95  TYR   B CE2 1 
ATOM   3224 C  CZ  . TYR   B 1 98  ? 10.34740  6.26826  -20.47374 1.000 71.18494  ? 95  TYR   B CZ  1 
ATOM   3225 O  OH  . TYR   B 1 98  ? 11.38772  6.50293  -19.60810 1.000 71.52645  ? 95  TYR   B OH  1 
ATOM   3226 N  N   . PRO   B 1 99  ? 3.72479   3.95240  -23.06107 1.000 71.24206  ? 96  PRO   B N   1 
ATOM   3227 C  CA  . PRO   B 1 99  ? 2.57609   3.72763  -23.93982 1.000 61.63041  ? 96  PRO   B CA  1 
ATOM   3228 C  C   . PRO   B 1 99  ? 1.89330   5.02597  -24.33315 1.000 66.75018  ? 96  PRO   B C   1 
ATOM   3229 O  O   . PRO   B 1 99  ? 1.94624   6.03063  -23.62159 1.000 67.47363  ? 96  PRO   B O   1 
ATOM   3230 C  CB  . PRO   B 1 99  ? 1.64708   2.86495  -23.07932 1.000 61.13810  ? 96  PRO   B CB  1 
ATOM   3231 C  CG  . PRO   B 1 99  ? 1.93763   3.31359  -21.69242 1.000 66.96639  ? 96  PRO   B CG  1 
ATOM   3232 C  CD  . PRO   B 1 99  ? 3.41082   3.63955  -21.65616 1.000 74.76244  ? 96  PRO   B CD  1 
ATOM   3233 N  N   . GLN   B 1 100 ? 1.24468   4.98578  -25.49509 1.000 73.05481  ? 97  GLN   B N   1 
ATOM   3234 C  CA  . GLN   B 1 100 ? 0.41332   6.09150  -25.95592 1.000 62.56383  ? 97  GLN   B CA  1 
ATOM   3235 C  C   . GLN   B 1 100 ? -0.97829  5.95938  -25.34860 1.000 60.51616  ? 97  GLN   B C   1 
ATOM   3236 O  O   . GLN   B 1 100 ? -1.66117  4.95138  -25.55977 1.000 63.40403  ? 97  GLN   B O   1 
ATOM   3237 C  CB  . GLN   B 1 100 ? 0.34289   6.10167  -27.47899 1.000 63.33887  ? 97  GLN   B CB  1 
ATOM   3238 C  CG  . GLN   B 1 100 ? 1.62395   6.55612  -28.14339 1.000 64.18503  ? 97  GLN   B CG  1 
ATOM   3239 C  CD  . GLN   B 1 100 ? 1.86185   8.04173  -27.97427 1.000 79.31564  ? 97  GLN   B CD  1 
ATOM   3240 O  OE1 . GLN   B 1 100 ? 2.94187   8.46534  -27.56172 1.000 77.09023  ? 97  GLN   B OE1 1 
ATOM   3241 N  NE2 . GLN   B 1 100 ? 0.85133   8.84467  -28.29829 1.000 74.10709  ? 97  GLN   B NE2 1 
ATOM   3242 N  N   . VAL   B 1 101 ? -1.39399  6.96745  -24.58781 1.000 55.42849  ? 98  VAL   B N   1 
ATOM   3243 C  CA  . VAL   B 1 101 ? -2.66155  6.94755  -23.86785 1.000 51.82942  ? 98  VAL   B CA  1 
ATOM   3244 C  C   . VAL   B 1 101 ? -3.41807  8.21982  -24.22233 1.000 59.18449  ? 98  VAL   B C   1 
ATOM   3245 O  O   . VAL   B 1 101 ? -2.96961  9.32441  -23.88876 1.000 58.90925  ? 98  VAL   B O   1 
ATOM   3246 C  CB  . VAL   B 1 101 ? -2.46145  6.83857  -22.34885 1.000 63.72410  ? 98  VAL   B CB  1 
ATOM   3247 C  CG1 . VAL   B 1 101 ? -3.80238  6.87829  -21.62573 1.000 62.16258  ? 98  VAL   B CG1 1 
ATOM   3248 C  CG2 . VAL   B 1 101 ? -1.70183  5.56992  -22.00314 1.000 57.89862  ? 98  VAL   B CG2 1 
ATOM   3249 N  N   . ASN   B 1 102 ? -4.55760  8.06808  -24.90175 1.000 64.88679  ? 99  ASN   B N   1 
ATOM   3250 C  CA  . ASN   B 1 102 ? -5.41982  9.19306  -25.27106 1.000 60.78371  ? 99  ASN   B CA  1 
ATOM   3251 C  C   . ASN   B 1 102 ? -4.65460  10.24369 -26.07415 1.000 63.63500  ? 99  ASN   B C   1 
ATOM   3252 O  O   . ASN   B 1 102 ? -4.80032  11.44907 -25.85726 1.000 62.82004  ? 99  ASN   B O   1 
ATOM   3253 C  CB  . ASN   B 1 102 ? -6.06577  9.81222  -24.02809 1.000 62.09206  ? 99  ASN   B CB  1 
ATOM   3254 C  CG  . ASN   B 1 102 ? -7.23051  10.71896 -24.36433 1.000 67.74459  ? 99  ASN   B CG  1 
ATOM   3255 O  OD1 . ASN   B 1 102 ? -7.23717  11.89986 -24.00990 1.000 65.54980  ? 99  ASN   B OD1 1 
ATOM   3256 N  ND2 . ASN   B 1 102 ? -8.21856  10.17452 -25.06540 1.000 63.46680  ? 99  ASN   B ND2 1 
ATOM   3257 N  N   . GLY   B 1 103 ? -3.82779  9.78347  -27.01048 1.000 58.16384  ? 100 GLY   B N   1 
ATOM   3258 C  CA  . GLY   B 1 103 ? -3.04659  10.70430 -27.81129 1.000 63.35272  ? 100 GLY   B CA  1 
ATOM   3259 C  C   . GLY   B 1 103 ? -1.89877  11.35858 -27.07904 1.000 66.15104  ? 100 GLY   B C   1 
ATOM   3260 O  O   . GLY   B 1 103 ? -1.34740  12.34849 -27.56810 1.000 68.00280  ? 100 GLY   B O   1 
ATOM   3261 N  N   . LEU   B 1 104 ? -1.52094  10.83214 -25.91557 1.000 65.12802  ? 101 LEU   B N   1 
ATOM   3262 C  CA  . LEU   B 1 104 ? -0.43352  11.37497 -25.11669 1.000 62.66058  ? 101 LEU   B CA  1 
ATOM   3263 C  C   . LEU   B 1 104 ? 0.54050   10.26254 -24.75905 1.000 62.30087  ? 101 LEU   B C   1 
ATOM   3264 O  O   . LEU   B 1 104 ? 0.16073   9.09307  -24.65603 1.000 62.57379  ? 101 LEU   B O   1 
ATOM   3265 C  CB  . LEU   B 1 104 ? -0.95688  12.03792 -23.83530 1.000 54.48911  ? 101 LEU   B CB  1 
ATOM   3266 C  CG  . LEU   B 1 104 ? -1.83057  13.27936 -24.01601 1.000 54.13598  ? 101 LEU   B CG  1 
ATOM   3267 C  CD1 . LEU   B 1 104 ? -2.67431  13.51573 -22.78062 1.000 55.49444  ? 101 LEU   B CD1 1 
ATOM   3268 C  CD2 . LEU   B 1 104 ? -0.96856  14.49484 -24.30963 1.000 53.47028  ? 101 LEU   B CD2 1 
ATOM   3269 N  N   . THR   B 1 105 ? 1.80587   10.63523 -24.58380 1.000 63.67380  ? 102 THR   B N   1 
ATOM   3270 C  CA  . THR   B 1 105 ? 2.83419   9.69821  -24.14863 1.000 62.90322  ? 102 THR   B CA  1 
ATOM   3271 C  C   . THR   B 1 105 ? 2.84025   9.64240  -22.62710 1.000 61.22323  ? 102 THR   B C   1 
ATOM   3272 O  O   . THR   B 1 105 ? 3.11723   10.64906 -21.96715 1.000 60.54078  ? 102 THR   B O   1 
ATOM   3273 C  CB  . THR   B 1 105 ? 4.21323   10.10478 -24.66417 1.000 63.23449  ? 102 THR   B CB  1 
ATOM   3274 O  OG1 . THR   B 1 105 ? 4.18387   10.21890 -26.09083 1.000 63.28189  ? 102 THR   B OG1 1 
ATOM   3275 C  CG2 . THR   B 1 105 ? 5.25240   9.06473  -24.26282 1.000 59.76456  ? 102 THR   B CG2 1 
ATOM   3276 N  N   . SER   B 1 106 ? 2.54248   8.47230  -22.07574 1.000 66.19890  ? 103 SER   B N   1 
ATOM   3277 C  CA  . SER   B 1 106 ? 2.53901   8.26228  -20.63836 1.000 69.12764  ? 103 SER   B CA  1 
ATOM   3278 C  C   . SER   B 1 106 ? 3.68311   7.32190  -20.25958 1.000 67.70833  ? 103 SER   B C   1 
ATOM   3279 O  O   . SER   B 1 106 ? 4.52938   6.96915  -21.08735 1.000 67.64962  ? 103 SER   B O   1 
ATOM   3280 C  CB  . SER   B 1 106 ? 1.17856   7.72546  -20.19337 1.000 63.98628  ? 103 SER   B CB  1 
ATOM   3281 O  OG  . SER   B 1 106 ? 1.01273   7.87173  -18.79675 1.000 61.39107  ? 103 SER   B OG  1 
ATOM   3282 N  N   . ILE   B 1 107 ? 3.71753   6.91266  -18.99526 1.000 71.34586  ? 104 ILE   B N   1 
ATOM   3283 C  CA  . ILE   B 1 107 ? 4.73506   5.98816  -18.50924 1.000 72.57449  ? 104 ILE   B CA  1 
ATOM   3284 C  C   . ILE   B 1 107 ? 4.02553   4.86787  -17.76879 1.000 70.76631  ? 104 ILE   B C   1 
ATOM   3285 O  O   . ILE   B 1 107 ? 3.26076   5.12834  -16.83198 1.000 70.19788  ? 104 ILE   B O   1 
ATOM   3286 C  CB  . ILE   B 1 107 ? 5.76068   6.66839  -17.58484 1.000 62.35857  ? 104 ILE   B CB  1 
ATOM   3287 C  CG1 . ILE   B 1 107 ? 6.07875   8.08546  -18.05796 1.000 67.20691  ? 104 ILE   B CG1 1 
ATOM   3288 C  CG2 . ILE   B 1 107 ? 7.03899   5.84859  -17.52866 1.000 69.43317  ? 104 ILE   B CG2 1 
ATOM   3289 C  CD1 . ILE   B 1 107 ? 6.98476   8.84070  -17.12034 1.000 59.14366  ? 104 ILE   B CD1 1 
ATOM   3290 N  N   . LYS   B 1 108 ? 4.26754   3.62839  -18.18856 1.000 70.86704  ? 105 LYS   B N   1 
ATOM   3291 C  CA  . LYS   B 1 108 ? 3.83164   2.49133  -17.39125 1.000 78.96097  ? 105 LYS   B CA  1 
ATOM   3292 C  C   . LYS   B 1 108 ? 4.54375   2.52055  -16.04500 1.000 77.21769  ? 105 LYS   B C   1 
ATOM   3293 O  O   . LYS   B 1 108 ? 5.74495   2.79343  -15.97068 1.000 75.55096  ? 105 LYS   B O   1 
ATOM   3294 C  CB  . LYS   B 1 108 ? 4.11576   1.18285  -18.12976 1.000 74.49539  ? 105 LYS   B CB  1 
ATOM   3295 C  CG  . LYS   B 1 108 ? 3.70743   -0.06581 -17.36709 1.000 80.05433  ? 105 LYS   B CG  1 
ATOM   3296 C  CD  . LYS   B 1 108 ? 4.17236   -1.32228 -18.08098 1.000 85.01205  ? 105 LYS   B CD  1 
ATOM   3297 C  CE  . LYS   B 1 108 ? 3.69653   -2.57184 -17.36146 1.000 92.19500  ? 105 LYS   B CE  1 
ATOM   3298 N  NZ  . LYS   B 1 108 ? 4.18108   -3.80682 -18.03615 1.000 105.32981 ? 105 LYS   B NZ  1 
ATOM   3299 N  N   . TRP   B 1 109 ? 3.79780   2.24382  -14.97563 1.000 79.20067  ? 106 TRP   B N   1 
ATOM   3300 C  CA  . TRP   B 1 109 ? 4.33162   2.45684  -13.63591 1.000 81.01949  ? 106 TRP   B CA  1 
ATOM   3301 C  C   . TRP   B 1 109 ? 5.55853   1.59073  -13.38356 1.000 81.74053  ? 106 TRP   B C   1 
ATOM   3302 O  O   . TRP   B 1 109 ? 5.58197   0.39834  -13.70402 1.000 81.97698  ? 106 TRP   B O   1 
ATOM   3303 C  CB  . TRP   B 1 109 ? 3.27866   2.16322  -12.56801 1.000 76.50063  ? 106 TRP   B CB  1 
ATOM   3304 C  CG  . TRP   B 1 109 ? 3.76510   2.52124  -11.19125 1.000 81.80926  ? 106 TRP   B CG  1 
ATOM   3305 C  CD1 . TRP   B 1 109 ? 3.60883   3.71737  -10.55144 1.000 82.30056  ? 106 TRP   B CD1 1 
ATOM   3306 C  CD2 . TRP   B 1 109 ? 4.52212   1.68840  -10.30220 1.000 82.86104  ? 106 TRP   B CD2 1 
ATOM   3307 N  NE1 . TRP   B 1 109 ? 4.20412   3.67474  -9.31320  1.000 86.01897  ? 106 TRP   B NE1 1 
ATOM   3308 C  CE2 . TRP   B 1 109 ? 4.77310   2.44099  -9.13676  1.000 85.57428  ? 106 TRP   B CE2 1 
ATOM   3309 C  CE3 . TRP   B 1 109 ? 5.00390   0.37684  -10.37495 1.000 80.52930  ? 106 TRP   B CE3 1 
ATOM   3310 C  CZ2 . TRP   B 1 109 ? 5.48459   1.92673  -8.05517  1.000 83.07723  ? 106 TRP   B CZ2 1 
ATOM   3311 C  CZ3 . TRP   B 1 109 ? 5.71072   -0.13075 -9.30140  1.000 74.75163  ? 106 TRP   B CZ3 1 
ATOM   3312 C  CH2 . TRP   B 1 109 ? 5.94410   0.64214  -8.15680  1.000 79.88987  ? 106 TRP   B CH2 1 
ATOM   3313 N  N   . ALA   B 1 110 ? 6.57412   2.20698  -12.78531 1.000 75.29102  ? 107 ALA   B N   1 
ATOM   3314 C  CA  . ALA   B 1 110 ? 7.80924   1.55234  -12.38283 1.000 78.22933  ? 107 ALA   B CA  1 
ATOM   3315 C  C   . ALA   B 1 110 ? 8.60580   2.52838  -11.53172 1.000 82.52623  ? 107 ALA   B C   1 
ATOM   3316 O  O   . ALA   B 1 110 ? 8.57402   3.73870  -11.76575 1.000 82.84353  ? 107 ALA   B O   1 
ATOM   3317 C  CB  . ALA   B 1 110 ? 8.63796   1.09740  -13.59063 1.000 71.14141  ? 107 ALA   B CB  1 
ATOM   3318 N  N   . ASP   B 1 111 ? 9.31448   1.98303  -10.54442 1.000 73.64610  ? 108 ASP   B N   1 
ATOM   3319 C  CA  . ASP   B 1 111 ? 10.26403  2.73602  -9.72455  1.000 62.58308  ? 108 ASP   B CA  1 
ATOM   3320 C  C   . ASP   B 1 111 ? 9.64608   4.02444  -9.18108  1.000 69.87132  ? 108 ASP   B C   1 
ATOM   3321 O  O   . ASP   B 1 111 ? 10.28270  5.08107  -9.15644  1.000 72.78218  ? 108 ASP   B O   1 
ATOM   3322 C  CB  . ASP   B 1 111 ? 11.54913  3.04050  -10.49631 1.000 66.57687  ? 108 ASP   B CB  1 
ATOM   3323 C  CG  . ASP   B 1 111 ? 12.23549  1.78985  -11.01193 1.000 70.85669  ? 108 ASP   B CG  1 
ATOM   3324 O  OD1 . ASP   B 1 111 ? 12.00837  0.70339  -10.43945 1.000 80.63340  ? 108 ASP   B OD1 1 
ATOM   3325 O  OD2 . ASP   B 1 111 ? 13.06468  1.90906  -11.94154 1.000 66.20812  ? 108 ASP   B OD2 1 
ATOM   3326 N  N   . ASN   B 1 112 ? 8.37505   3.94159  -8.78431  1.000 70.31780  ? 109 ASN   B N   1 
ATOM   3327 C  CA  . ASN   B 1 112 ? 7.67530   5.03470  -8.10367  1.000 74.29478  ? 109 ASN   B CA  1 
ATOM   3328 C  C   . ASN   B 1 112 ? 7.63429   6.30647  -8.95418  1.000 75.95386  ? 109 ASN   B C   1 
ATOM   3329 O  O   . ASN   B 1 112 ? 7.91110   7.40878  -8.47486  1.000 73.14054  ? 109 ASN   B O   1 
ATOM   3330 C  CB  . ASN   B 1 112 ? 8.31908   5.32133  -6.74199  1.000 90.13156  ? 109 ASN   B CB  1 
ATOM   3331 C  CG  . ASN   B 1 112 ? 8.25324   4.13410  -5.79446  1.000 89.01407  ? 109 ASN   B CG  1 
ATOM   3332 O  OD1 . ASN   B 1 112 ? 7.25426   3.41524  -5.73647  1.000 83.26224  ? 109 ASN   B OD1 1 
ATOM   3333 N  ND2 . ASN   B 1 112 ? 9.33162   3.92297  -5.04582  1.000 82.48497  ? 109 ASN   B ND2 1 
ATOM   3334 N  N   . ASN   B 1 113 ? 7.27052   6.15050  -10.22969 1.000 85.45470  ? 110 ASN   B N   1 
ATOM   3335 C  CA  . ASN   B 1 113 ? 7.25584   7.25688  -11.18012 1.000 77.55127  ? 110 ASN   B CA  1 
ATOM   3336 C  C   . ASN   B 1 113 ? 5.86668   7.86315  -11.36965 1.000 71.72766  ? 110 ASN   B C   1 
ATOM   3337 O  O   . ASN   B 1 113 ? 5.60389   8.46292  -12.41672 1.000 70.93056  ? 110 ASN   B O   1 
ATOM   3338 C  CB  . ASN   B 1 113 ? 7.82185   6.80890  -12.53208 1.000 71.90098  ? 110 ASN   B CB  1 
ATOM   3339 C  CG  . ASN   B 1 113 ? 7.03026   5.67154  -13.15680 1.000 76.74536  ? 110 ASN   B CG  1 
ATOM   3340 O  OD1 . ASN   B 1 113 ? 5.98944   5.26381  -12.64114 1.000 80.81495  ? 110 ASN   B OD1 1 
ATOM   3341 N  ND2 . ASN   B 1 113 ? 7.53057   5.14557  -14.27037 1.000 64.80636  ? 110 ASN   B ND2 1 
ATOM   3342 N  N   . CYS   B 1 114 ? 4.97244   7.71044  -10.38840 1.000 73.51135  ? 111 CYS   B N   1 
ATOM   3343 C  CA  . CYS   B 1 114 ? 3.61831   8.24275  -10.53144 1.000 73.16744  ? 111 CYS   B CA  1 
ATOM   3344 C  C   . CYS   B 1 114 ? 3.63134   9.73331  -10.85238 1.000 68.74133  ? 111 CYS   B C   1 
ATOM   3345 O  O   . CYS   B 1 114 ? 2.88789   10.19205 -11.72891 1.000 77.02942  ? 111 CYS   B O   1 
ATOM   3346 C  CB  . CYS   B 1 114 ? 2.80912   7.98103  -9.25904  1.000 72.65002  ? 111 CYS   B CB  1 
ATOM   3347 S  SG  . CYS   B 1 114 ? 3.11015   9.16636  -7.91442  1.000 105.28439 ? 111 CYS   B SG  1 
ATOM   3348 N  N   . TYR   B 1 115 ? 4.47111   10.50483 -10.16268 1.000 66.54063  ? 112 TYR   B N   1 
ATOM   3349 C  CA  . TYR   B 1 115 ? 4.49403   11.94564 -10.39392 1.000 67.36630  ? 112 TYR   B CA  1 
ATOM   3350 C  C   . TYR   B 1 115 ? 5.14603   12.29728 -11.72601 1.000 62.34609  ? 112 TYR   B C   1 
ATOM   3351 O  O   . TYR   B 1 115 ? 4.76508   13.29310 -12.35178 1.000 63.75712  ? 112 TYR   B O   1 
ATOM   3352 C  CB  . TYR   B 1 115 ? 5.20280   12.65541 -9.23665  1.000 63.40635  ? 112 TYR   B CB  1 
ATOM   3353 C  CG  . TYR   B 1 115 ? 6.70880   12.54173 -9.26281  1.000 59.36196  ? 112 TYR   B CG  1 
ATOM   3354 C  CD1 . TYR   B 1 115 ? 7.33717   11.33878 -8.97060  1.000 64.61336  ? 112 TYR   B CD1 1 
ATOM   3355 C  CD2 . TYR   B 1 115 ? 7.50469   13.64151 -9.56218  1.000 60.92641  ? 112 TYR   B CD2 1 
ATOM   3356 C  CE1 . TYR   B 1 115 ? 8.71567   11.22714 -8.98941  1.000 70.96606  ? 112 TYR   B CE1 1 
ATOM   3357 C  CE2 . TYR   B 1 115 ? 8.88786   13.54130 -9.58258  1.000 58.36793  ? 112 TYR   B CE2 1 
ATOM   3358 C  CZ  . TYR   B 1 115 ? 9.48718   12.33021 -9.29489  1.000 69.49273  ? 112 TYR   B CZ  1 
ATOM   3359 O  OH  . TYR   B 1 115 ? 10.86027  12.21624 -9.30989  1.000 72.34454  ? 112 TYR   B OH  1 
ATOM   3360 N  N   . LEU   B 1 116 ? 6.12246   11.50210 -12.17355 1.000 60.48853  ? 113 LEU   B N   1 
ATOM   3361 C  CA  . LEU   B 1 116 ? 6.76080   11.76537 -13.46077 1.000 67.93362  ? 113 LEU   B CA  1 
ATOM   3362 C  C   . LEU   B 1 116 ? 5.78104   11.60075 -14.61678 1.000 68.47223  ? 113 LEU   B C   1 
ATOM   3363 O  O   . LEU   B 1 116 ? 5.74918   12.43446 -15.53072 1.000 61.35509  ? 113 LEU   B O   1 
ATOM   3364 C  CB  . LEU   B 1 116 ? 7.96325   10.84042 -13.65430 1.000 67.35643  ? 113 LEU   B CB  1 
ATOM   3365 C  CG  . LEU   B 1 116 ? 9.30448   11.29413 -13.07976 1.000 72.68135  ? 113 LEU   B CG  1 
ATOM   3366 C  CD1 . LEU   B 1 116 ? 10.36107  10.23165 -13.33419 1.000 74.87502  ? 113 LEU   B CD1 1 
ATOM   3367 C  CD2 . LEU   B 1 116 ? 9.72730   12.63234 -13.67799 1.000 61.80517  ? 113 LEU   B CD2 1 
ATOM   3368 N  N   . ALA   B 1 117 ? 4.97935   10.53070 -14.59655 1.000 61.64947  ? 114 ALA   B N   1 
ATOM   3369 C  CA  . ALA   B 1 117 ? 3.98381   10.33218 -15.64301 1.000 57.23915  ? 114 ALA   B CA  1 
ATOM   3370 C  C   . ALA   B 1 117 ? 2.99791   11.49286 -15.68762 1.000 61.55509  ? 114 ALA   B C   1 
ATOM   3371 O  O   . ALA   B 1 117 ? 2.66696   11.99331 -16.76695 1.000 63.23224  ? 114 ALA   B O   1 
ATOM   3372 C  CB  . ALA   B 1 117 ? 3.25584   9.00488  -15.43098 1.000 53.77879  ? 114 ALA   B CB  1 
ATOM   3373 N  N   . THR   B 1 118 ? 2.53070   11.94654 -14.52394 1.000 60.85063  ? 115 THR   B N   1 
ATOM   3374 C  CA  . THR   B 1 118 ? 1.61732   13.08348 -14.49408 1.000 61.97598  ? 115 THR   B CA  1 
ATOM   3375 C  C   . THR   B 1 118 ? 2.30526   14.34737 -14.99554 1.000 60.81626  ? 115 THR   B C   1 
ATOM   3376 O  O   . THR   B 1 118 ? 1.69778   15.15336 -15.71172 1.000 57.36254  ? 115 THR   B O   1 
ATOM   3377 C  CB  . THR   B 1 118 ? 1.08210   13.28327 -13.07672 1.000 65.84361  ? 115 THR   B CB  1 
ATOM   3378 O  OG1 . THR   B 1 118 ? 0.32148   12.13057 -12.69158 1.000 61.81435  ? 115 THR   B OG1 1 
ATOM   3379 C  CG2 . THR   B 1 118 ? 0.19887   14.52951 -12.99500 1.000 57.87959  ? 115 THR   B CG2 1 
ATOM   3380 N  N   . ALA   B 1 119 ? 3.57386   14.53638 -14.63111 1.000 58.61693  ? 116 ALA   B N   1 
ATOM   3381 C  CA  . ALA   B 1 119 ? 4.31942   15.68857 -15.12370 1.000 56.94958  ? 116 ALA   B CA  1 
ATOM   3382 C  C   . ALA   B 1 119 ? 4.50562   15.60938 -16.63276 1.000 65.73796  ? 116 ALA   B C   1 
ATOM   3383 O  O   . ALA   B 1 119 ? 4.30393   16.59670 -17.34986 1.000 62.51559  ? 116 ALA   B O   1 
ATOM   3384 C  CB  . ALA   B 1 119 ? 5.67145   15.77258 -14.41676 1.000 44.38594  ? 116 ALA   B CB  1 
ATOM   3385 N  N   . LEU   B 1 120 ? 4.88748   14.43197 -17.13247 1.000 58.36072  ? 117 LEU   B N   1 
ATOM   3386 C  CA  . LEU   B 1 120 ? 5.09627   14.26204 -18.56634 1.000 54.33041  ? 117 LEU   B CA  1 
ATOM   3387 C  C   . LEU   B 1 120 ? 3.82154   14.53881 -19.35237 1.000 57.51075  ? 117 LEU   B C   1 
ATOM   3388 O  O   . LEU   B 1 120 ? 3.85805   15.20868 -20.39170 1.000 59.77550  ? 117 LEU   B O   1 
ATOM   3389 C  CB  . LEU   B 1 120 ? 5.60777   12.85143 -18.85242 1.000 53.29441  ? 117 LEU   B CB  1 
ATOM   3390 C  CG  . LEU   B 1 120 ? 5.83866   12.51489 -20.32296 1.000 47.85969  ? 117 LEU   B CG  1 
ATOM   3391 C  CD1 . LEU   B 1 120 ? 6.83451   13.48748 -20.92459 1.000 48.84366  ? 117 LEU   B CD1 1 
ATOM   3392 C  CD2 . LEU   B 1 120 ? 6.32952   11.08146 -20.46662 1.000 53.92700  ? 117 LEU   B CD2 1 
ATOM   3393 N  N   . LEU   B 1 121 ? 2.68566   14.02433 -18.87493 1.000 54.75660  ? 118 LEU   B N   1 
ATOM   3394 C  CA  . LEU   B 1 121 ? 1.41982   14.25449 -19.56215 1.000 52.57014  ? 118 LEU   B CA  1 
ATOM   3395 C  C   . LEU   B 1 121 ? 1.06025   15.73385 -19.57111 1.000 57.96680  ? 118 LEU   B C   1 
ATOM   3396 O  O   . LEU   B 1 121 ? 0.53297   16.24787 -20.56382 1.000 59.69009  ? 118 LEU   B O   1 
ATOM   3397 C  CB  . LEU   B 1 121 ? 0.30941   13.43155 -18.90922 1.000 48.97561  ? 118 LEU   B CB  1 
ATOM   3398 C  CG  . LEU   B 1 121 ? 0.46720   11.91062 -19.00642 1.000 58.98544  ? 118 LEU   B CG  1 
ATOM   3399 C  CD1 . LEU   B 1 121 ? -0.48583  11.21850 -18.05526 1.000 62.22727  ? 118 LEU   B CD1 1 
ATOM   3400 C  CD2 . LEU   B 1 121 ? 0.25351   11.41747 -20.42905 1.000 57.05199  ? 118 LEU   B CD2 1 
ATOM   3401 N  N   . THR   B 1 122 ? 1.34805   16.43726 -18.47767 1.000 55.45764  ? 119 THR   B N   1 
ATOM   3402 C  CA  . THR   B 1 122 ? 1.05836   17.86460 -18.43067 1.000 52.43257  ? 119 THR   B CA  1 
ATOM   3403 C  C   . THR   B 1 122 ? 1.92169   18.63659 -19.42131 1.000 58.67076  ? 119 THR   B C   1 
ATOM   3404 O  O   . THR   B 1 122 ? 1.42083   19.50938 -20.14193 1.000 60.81361  ? 119 THR   B O   1 
ATOM   3405 C  CB  . THR   B 1 122 ? 1.27921   18.39156 -17.01758 1.000 55.29170  ? 119 THR   B CB  1 
ATOM   3406 O  OG1 . THR   B 1 122 ? 0.37978   17.73472 -16.11655 1.000 57.92087  ? 119 THR   B OG1 1 
ATOM   3407 C  CG2 . THR   B 1 122 ? 1.03889   19.88490 -16.98556 1.000 50.56222  ? 119 THR   B CG2 1 
ATOM   3408 N  N   . LEU   B 1 123 ? 3.21889   18.32515 -19.47404 1.000 58.75874  ? 120 LEU   B N   1 
ATOM   3409 C  CA  . LEU   B 1 123 ? 4.12788   19.06285 -20.34418 1.000 61.27499  ? 120 LEU   B CA  1 
ATOM   3410 C  C   . LEU   B 1 123 ? 3.71555   18.97092 -21.80740 1.000 61.28213  ? 120 LEU   B C   1 
ATOM   3411 O  O   . LEU   B 1 123 ? 3.96681   19.90341 -22.57860 1.000 62.16300  ? 120 LEU   B O   1 
ATOM   3412 C  CB  . LEU   B 1 123 ? 5.55488   18.55063 -20.15863 1.000 58.38847  ? 120 LEU   B CB  1 
ATOM   3413 C  CG  . LEU   B 1 123 ? 6.17330   18.80956 -18.78510 1.000 58.94320  ? 120 LEU   B CG  1 
ATOM   3414 C  CD1 . LEU   B 1 123 ? 7.43491   17.97643 -18.61021 1.000 56.42230  ? 120 LEU   B CD1 1 
ATOM   3415 C  CD2 . LEU   B 1 123 ? 6.45969   20.29364 -18.59476 1.000 50.67422  ? 120 LEU   B CD2 1 
ATOM   3416 N  N   . GLN   B 1 124 ? 3.07866   17.86995 -22.20797 1.000 53.57668  ? 121 GLN   B N   1 
ATOM   3417 C  CA  . GLN   B 1 124 ? 2.63764   17.70213 -23.58801 1.000 55.99869  ? 121 GLN   B CA  1 
ATOM   3418 C  C   . GLN   B 1 124 ? 1.38193   18.49864 -23.91437 1.000 55.16300  ? 121 GLN   B C   1 
ATOM   3419 O  O   . GLN   B 1 124 ? 0.92128   18.45009 -25.05873 1.000 60.17083  ? 121 GLN   B O   1 
ATOM   3420 C  CB  . GLN   B 1 124 ? 2.38614   16.22265 -23.88978 1.000 47.42008  ? 121 GLN   B CB  1 
ATOM   3421 C  CG  . GLN   B 1 124 ? 3.61980   15.35565 -23.79674 1.000 47.24973  ? 121 GLN   B CG  1 
ATOM   3422 C  CD  . GLN   B 1 124 ? 3.29751   13.87866 -23.84427 1.000 51.06467  ? 121 GLN   B CD  1 
ATOM   3423 O  OE1 . GLN   B 1 124 ? 3.02724   13.32194 -24.90922 1.000 60.41838  ? 121 GLN   B OE1 1 
ATOM   3424 N  NE2 . GLN   B 1 124 ? 3.31995   13.23379 -22.68564 1.000 60.98957  ? 121 GLN   B NE2 1 
ATOM   3425 N  N   . GLN   B 1 125 ? 0.82031   19.22539 -22.94942 1.000 56.69860  ? 122 GLN   B N   1 
ATOM   3426 C  CA  . GLN   B 1 125 ? -0.42735  19.94454 -23.14907 1.000 47.89210  ? 122 GLN   B CA  1 
ATOM   3427 C  C   . GLN   B 1 125 ? -0.31920  21.44042 -22.88674 1.000 52.83486  ? 122 GLN   B C   1 
ATOM   3428 O  O   . GLN   B 1 125 ? -1.33454  22.14095 -22.97052 1.000 61.45190  ? 122 GLN   B O   1 
ATOM   3429 C  CB  . GLN   B 1 125 ? -1.52567  19.33939 -22.26314 1.000 49.13938  ? 122 GLN   B CB  1 
ATOM   3430 C  CG  . GLN   B 1 125 ? -1.79104  17.86858 -22.55730 1.000 51.07167  ? 122 GLN   B CG  1 
ATOM   3431 C  CD  . GLN   B 1 125 ? -2.77545  17.23847 -21.59288 1.000 61.54150  ? 122 GLN   B CD  1 
ATOM   3432 O  OE1 . GLN   B 1 125 ? -3.95007  17.60228 -21.55840 1.000 65.13875  ? 122 GLN   B OE1 1 
ATOM   3433 N  NE2 . GLN   B 1 125 ? -2.29973  16.28165 -20.80567 1.000 58.27201  ? 122 GLN   B NE2 1 
ATOM   3434 N  N   . ILE   B 1 126 ? 0.86876   21.95264 -22.57790 1.000 54.17561  ? 123 ILE   B N   1 
ATOM   3435 C  CA  . ILE   B 1 126 ? 1.07852   23.38316 -22.39857 1.000 59.67721  ? 123 ILE   B CA  1 
ATOM   3436 C  C   . ILE   B 1 126 ? 2.19451   23.83060 -23.33040 1.000 62.88684  ? 123 ILE   B C   1 
ATOM   3437 O  O   . ILE   B 1 126 ? 3.09071   23.05361 -23.67470 1.000 67.56108  ? 123 ILE   B O   1 
ATOM   3438 C  CB  . ILE   B 1 126 ? 1.41029   23.74577 -20.93510 1.000 67.64364  ? 123 ILE   B CB  1 
ATOM   3439 C  CG1 . ILE   B 1 126 ? 2.62899   22.95970 -20.44872 1.000 71.10733  ? 123 ILE   B CG1 1 
ATOM   3440 C  CG2 . ILE   B 1 126 ? 0.21587   23.48240 -20.03664 1.000 62.92197  ? 123 ILE   B CG2 1 
ATOM   3441 C  CD1 . ILE   B 1 126 ? 2.98663   23.23397 -19.00502 1.000 53.51125  ? 123 ILE   B CD1 1 
ATOM   3442 N  N   . GLU   B 1 127 ? 2.13434   25.09467 -23.74272 1.000 63.75273  ? 124 GLU   B N   1 
ATOM   3443 C  CA  . GLU   B 1 127 ? 3.11681   25.63570 -24.67422 1.000 62.63787  ? 124 GLU   B CA  1 
ATOM   3444 C  C   . GLU   B 1 127 ? 4.38523   26.00959 -23.91931 1.000 67.72448  ? 124 GLU   B C   1 
ATOM   3445 O  O   . GLU   B 1 127 ? 4.36400   26.89042 -23.05245 1.000 66.53148  ? 124 GLU   B O   1 
ATOM   3446 C  CB  . GLU   B 1 127 ? 2.55879   26.84813 -25.41251 1.000 69.15804  ? 124 GLU   B CB  1 
ATOM   3447 C  CG  . GLU   B 1 127 ? 3.48158   27.36380 -26.50613 1.000 81.22479  ? 124 GLU   B CG  1 
ATOM   3448 C  CD  . GLU   B 1 127 ? 2.83196   28.42982 -27.36579 1.000 116.81347 ? 124 GLU   B CD  1 
ATOM   3449 O  OE1 . GLU   B 1 127 ? 1.67650   28.80726 -27.07439 1.000 112.09155 ? 124 GLU   B OE1 1 
ATOM   3450 O  OE2 . GLU   B 1 127 ? 3.47283   28.88370 -28.33892 1.000 120.90850 ? 124 GLU   B OE2 1 
ATOM   3451 N  N   . LEU   B 1 128 ? 5.49013   25.34978 -24.25710 1.000 74.86869  ? 125 LEU   B N   1 
ATOM   3452 C  CA  . LEU   B 1 128 ? 6.72549   25.47915 -23.49747 1.000 65.87152  ? 125 LEU   B CA  1 
ATOM   3453 C  C   . LEU   B 1 128 ? 7.90777   25.27902 -24.43132 1.000 64.61818  ? 125 LEU   B C   1 
ATOM   3454 O  O   . LEU   B 1 128 ? 7.92269   24.32987 -25.22139 1.000 71.40053  ? 125 LEU   B O   1 
ATOM   3455 C  CB  . LEU   B 1 128 ? 6.77322   24.45518 -22.35812 1.000 66.91270  ? 125 LEU   B CB  1 
ATOM   3456 C  CG  . LEU   B 1 128 ? 7.35614   24.88039 -21.01151 1.000 66.34108  ? 125 LEU   B CG  1 
ATOM   3457 C  CD1 . LEU   B 1 128 ? 6.70381   26.15904 -20.52520 1.000 68.71410  ? 125 LEU   B CD1 1 
ATOM   3458 C  CD2 . LEU   B 1 128 ? 7.17210   23.76676 -19.99381 1.000 67.12955  ? 125 LEU   B CD2 1 
ATOM   3459 N  N   . LYS   B 1 129 ? 8.89283   26.16795 -24.33546 1.000 63.60753  ? 126 LYS   B N   1 
ATOM   3460 C  CA  . LYS   B 1 129 ? 10.16088  26.01619 -25.03660 1.000 63.97888  ? 126 LYS   B CA  1 
ATOM   3461 C  C   . LYS   B 1 129 ? 11.27991  26.02175 -24.00534 1.000 65.98380  ? 126 LYS   B C   1 
ATOM   3462 O  O   . LYS   B 1 129 ? 11.40905  26.97562 -23.23010 1.000 65.88955  ? 126 LYS   B O   1 
ATOM   3463 C  CB  . LYS   B 1 129 ? 10.36568  27.13019 -26.06340 1.000 63.34630  ? 126 LYS   B CB  1 
ATOM   3464 C  CG  . LYS   B 1 129 ? 11.47739  26.84290 -27.05929 1.000 73.30205  ? 126 LYS   B CG  1 
ATOM   3465 C  CD  . LYS   B 1 129 ? 11.94754  28.11023 -27.75472 1.000 89.86809  ? 126 LYS   B CD  1 
ATOM   3466 C  CE  . LYS   B 1 129 ? 12.95583  27.79730 -28.85236 1.000 116.62361 ? 126 LYS   B CE  1 
ATOM   3467 N  NZ  . LYS   B 1 129 ? 14.14741  27.06937 -28.32996 1.000 120.22986 ? 126 LYS   B NZ  1 
ATOM   3468 N  N   . PHE   B 1 130 ? 12.09004  24.96596 -24.00582 1.000 65.49469  ? 127 PHE   B N   1 
ATOM   3469 C  CA  . PHE   B 1 130 ? 13.17319  24.82159 -23.04402 1.000 59.70059  ? 127 PHE   B CA  1 
ATOM   3470 C  C   . PHE   B 1 130 ? 14.45067  25.45649 -23.57415 1.000 58.61705  ? 127 PHE   B C   1 
ATOM   3471 O  O   . PHE   B 1 130 ? 14.75713  25.36543 -24.76581 1.000 62.00020  ? 127 PHE   B O   1 
ATOM   3472 C  CB  . PHE   B 1 130 ? 13.41614  23.34656 -22.72312 1.000 57.08350  ? 127 PHE   B CB  1 
ATOM   3473 C  CG  . PHE   B 1 130 ? 12.31195  22.71450 -21.93156 1.000 61.48760  ? 127 PHE   B CG  1 
ATOM   3474 C  CD1 . PHE   B 1 130 ? 12.08660  23.08809 -20.61860 1.000 62.55422  ? 127 PHE   B CD1 1 
ATOM   3475 C  CD2 . PHE   B 1 130 ? 11.49556  21.75367 -22.50006 1.000 59.91958  ? 127 PHE   B CD2 1 
ATOM   3476 C  CE1 . PHE   B 1 130 ? 11.07014  22.51329 -19.88839 1.000 64.93044  ? 127 PHE   B CE1 1 
ATOM   3477 C  CE2 . PHE   B 1 130 ? 10.47718  21.17567 -21.77278 1.000 51.15279  ? 127 PHE   B CE2 1 
ATOM   3478 C  CZ  . PHE   B 1 130 ? 10.26397  21.55566 -20.46703 1.000 60.16235  ? 127 PHE   B CZ  1 
ATOM   3479 N  N   . ASN   B 1 131 ? 15.19279  26.10924 -22.67343 1.000 60.60888  ? 128 ASN   B N   1 
ATOM   3480 C  CA  . ASN   B 1 131 ? 16.44844  26.73803 -23.08139 1.000 56.95615  ? 128 ASN   B CA  1 
ATOM   3481 C  C   . ASN   B 1 131 ? 17.53444  25.71332 -23.39111 1.000 56.89325  ? 128 ASN   B C   1 
ATOM   3482 O  O   . ASN   B 1 131 ? 18.18194  25.83613 -24.44641 1.000 56.10400  ? 128 ASN   B O   1 
ATOM   3483 C  CB  . ASN   B 1 131 ? 16.90118  27.74267 -22.01570 1.000 59.07713  ? 128 ASN   B CB  1 
ATOM   3484 C  CG  . ASN   B 1 131 ? 15.89925  28.86077 -21.79918 1.000 61.19804  ? 128 ASN   B CG  1 
ATOM   3485 O  OD1 . ASN   B 1 131 ? 15.31398  29.38153 -22.74895 1.000 61.26281  ? 128 ASN   B OD1 1 
ATOM   3486 N  ND2 . ASN   B 1 131 ? 15.70258  29.24056 -20.54205 1.000 67.41676  ? 128 ASN   B ND2 1 
ATOM   3487 N  N   . PRO   B 1 132 ? 17.80575  24.71382 -22.54982 1.000 60.06024  ? 129 PRO   B N   1 
ATOM   3488 C  CA  . PRO   B 1 132 ? 18.84683  23.73860 -22.88794 1.000 56.71779  ? 129 PRO   B CA  1 
ATOM   3489 C  C   . PRO   B 1 132 ? 18.44929  22.91615 -24.09837 1.000 58.52674  ? 129 PRO   B C   1 
ATOM   3490 O  O   . PRO   B 1 132 ? 17.36938  22.30622 -24.11817 1.000 59.69756  ? 129 PRO   B O   1 
ATOM   3491 C  CB  . PRO   B 1 132 ? 18.93874  22.86059 -21.62925 1.000 53.85750  ? 129 PRO   B CB  1 
ATOM   3492 C  CG  . PRO   B 1 132 ? 18.36273  23.69014 -20.54619 1.000 60.74520  ? 129 PRO   B CG  1 
ATOM   3493 C  CD  . PRO   B 1 132 ? 17.26873  24.46362 -21.20014 1.000 55.05181  ? 129 PRO   B CD  1 
ATOM   3494 N  N   . PRO   B 1 133 ? 19.28967  22.88412 -25.13291 1.000 52.11641  ? 130 PRO   B N   1 
ATOM   3495 C  CA  . PRO   B 1 133 ? 19.00900  22.00428 -26.27666 1.000 54.38277  ? 130 PRO   B CA  1 
ATOM   3496 C  C   . PRO   B 1 133 ? 18.78303  20.55764 -25.88278 1.000 54.99104  ? 130 PRO   B C   1 
ATOM   3497 O  O   . PRO   B 1 133 ? 17.98425  19.86848 -26.52844 1.000 62.41399  ? 130 PRO   B O   1 
ATOM   3498 C  CB  . PRO   B 1 133 ? 20.26034  22.16574 -27.14892 1.000 49.93698  ? 130 PRO   B CB  1 
ATOM   3499 C  CG  . PRO   B 1 133 ? 20.77226  23.51686 -26.81109 1.000 51.75894  ? 130 PRO   B CG  1 
ATOM   3500 C  CD  . PRO   B 1 133 ? 20.49042  23.70786 -25.34867 1.000 52.99273  ? 130 PRO   B CD  1 
ATOM   3501 N  N   . ALA   B 1 134 ? 19.46279  20.07352 -24.84134 1.000 55.80931  ? 131 ALA   B N   1 
ATOM   3502 C  CA  . ALA   B 1 134 ? 19.24182  18.70552 -24.38395 1.000 59.60947  ? 131 ALA   B CA  1 
ATOM   3503 C  C   . ALA   B 1 134 ? 17.79031  18.49412 -23.97740 1.000 58.04312  ? 131 ALA   B C   1 
ATOM   3504 O  O   . ALA   B 1 134 ? 17.17332  17.48240 -24.33302 1.000 54.93599  ? 131 ALA   B O   1 
ATOM   3505 C  CB  . ALA   B 1 134 ? 20.17669  18.38038 -23.21977 1.000 56.81526  ? 131 ALA   B CB  1 
ATOM   3506 N  N   . LEU   B 1 135 ? 17.22905  19.44196 -23.22289 1.000 53.19858  ? 132 LEU   B N   1 
ATOM   3507 C  CA  . LEU   B 1 135 ? 15.83448  19.32904 -22.81026 1.000 52.74130  ? 132 LEU   B CA  1 
ATOM   3508 C  C   . LEU   B 1 135 ? 14.90120  19.43752 -24.00888 1.000 58.89879  ? 132 LEU   B C   1 
ATOM   3509 O  O   . LEU   B 1 135 ? 13.93941  18.66981 -24.12689 1.000 59.37314  ? 132 LEU   B O   1 
ATOM   3510 C  CB  . LEU   B 1 135 ? 15.50161  20.39875 -21.76955 1.000 52.04869  ? 132 LEU   B CB  1 
ATOM   3511 C  CG  . LEU   B 1 135 ? 15.43110  19.94851 -20.30686 1.000 46.39996  ? 132 LEU   B CG  1 
ATOM   3512 C  CD1 . LEU   B 1 135 ? 14.84624  21.04192 -19.43289 1.000 54.37327  ? 132 LEU   B CD1 1 
ATOM   3513 C  CD2 . LEU   B 1 135 ? 14.63031  18.66962 -20.15817 1.000 44.32732  ? 132 LEU   B CD2 1 
ATOM   3514 N  N   . GLN   B 1 136 ? 15.17226  20.38433 -24.91052 1.000 63.10801  ? 133 GLN   B N   1 
ATOM   3515 C  CA  . GLN   B 1 136 ? 14.29356  20.57805 -26.05869 1.000 55.66026  ? 133 GLN   B CA  1 
ATOM   3516 C  C   . GLN   B 1 136 ? 14.28241  19.35520 -26.96777 1.000 55.36890  ? 133 GLN   B C   1 
ATOM   3517 O  O   . GLN   B 1 136 ? 13.21297  18.92017 -27.41338 1.000 60.15636  ? 133 GLN   B O   1 
ATOM   3518 C  CB  . GLN   B 1 136 ? 14.71522  21.82403 -26.83510 1.000 58.18483  ? 133 GLN   B CB  1 
ATOM   3519 C  CG  . GLN   B 1 136 ? 13.66410  22.29912 -27.82345 1.000 69.26889  ? 133 GLN   B CG  1 
ATOM   3520 C  CD  . GLN   B 1 136 ? 12.29284  22.47328 -27.18681 1.000 75.74228  ? 133 GLN   B CD  1 
ATOM   3521 O  OE1 . GLN   B 1 136 ? 12.16051  23.05290 -26.10568 1.000 74.33078  ? 133 GLN   B OE1 1 
ATOM   3522 N  NE2 . GLN   B 1 136 ? 11.26433  21.97158 -27.85868 1.000 75.44600  ? 133 GLN   B NE2 1 
ATOM   3523 N  N   . ASP   B 1 137 ? 15.45676  18.78815 -27.25745 1.000 49.10411  ? 134 ASP   B N   1 
ATOM   3524 C  CA  . ASP   B 1 137 ? 15.51349  17.57851 -28.07648 1.000 50.92957  ? 134 ASP   B CA  1 
ATOM   3525 C  C   . ASP   B 1 137 ? 14.75267  16.43223 -27.42354 1.000 58.84803  ? 134 ASP   B C   1 
ATOM   3526 O  O   . ASP   B 1 137 ? 14.00131  15.71434 -28.09344 1.000 61.86466  ? 134 ASP   B O   1 
ATOM   3527 C  CB  . ASP   B 1 137 ? 16.96530  17.16748 -28.33099 1.000 56.96059  ? 134 ASP   B CB  1 
ATOM   3528 C  CG  . ASP   B 1 137 ? 17.68959  18.11196 -29.27127 1.000 72.44498  ? 134 ASP   B CG  1 
ATOM   3529 O  OD1 . ASP   B 1 137 ? 17.06087  19.07295 -29.75923 1.000 73.19486  ? 134 ASP   B OD1 1 
ATOM   3530 O  OD2 . ASP   B 1 137 ? 18.89568  17.88703 -29.52245 1.000 78.68508  ? 134 ASP   B OD2 1 
ATOM   3531 N  N   . ALA   B 1 138 ? 14.94394  16.23575 -26.11807 1.000 57.24192  ? 135 ALA   B N   1 
ATOM   3532 C  CA  . ALA   B 1 138 ? 14.25455  15.14832 -25.43767 1.000 53.93074  ? 135 ALA   B CA  1 
ATOM   3533 C  C   . ALA   B 1 138 ? 12.75491  15.39654 -25.36142 1.000 55.86572  ? 135 ALA   B C   1 
ATOM   3534 O  O   . ALA   B 1 138 ? 11.96763  14.44611 -25.43757 1.000 57.61648  ? 135 ALA   B O   1 
ATOM   3535 C  CB  . ALA   B 1 138 ? 14.83916  14.95493 -24.03930 1.000 58.86212  ? 135 ALA   B CB  1 
ATOM   3536 N  N   . TYR   B 1 139 ? 12.34894  16.66017 -25.21608 1.000 57.72214  ? 136 TYR   B N   1 
ATOM   3537 C  CA  . TYR   B 1 139 ? 10.93446  17.01993 -25.25494 1.000 56.57195  ? 136 TYR   B CA  1 
ATOM   3538 C  C   . TYR   B 1 139 ? 10.28393  16.52746 -26.54420 1.000 60.06507  ? 136 TYR   B C   1 
ATOM   3539 O  O   . TYR   B 1 139 ? 9.23220   15.87857 -26.51929 1.000 60.11774  ? 136 TYR   B O   1 
ATOM   3540 C  CB  . TYR   B 1 139 ? 10.80718  18.54030 -25.11300 1.000 58.65315  ? 136 TYR   B CB  1 
ATOM   3541 C  CG  . TYR   B 1 139 ? 9.42902   19.07723 -24.78054 1.000 64.30411  ? 136 TYR   B CG  1 
ATOM   3542 C  CD1 . TYR   B 1 139 ? 8.40054   18.23848 -24.37395 1.000 58.45157  ? 136 TYR   B CD1 1 
ATOM   3543 C  CD2 . TYR   B 1 139 ? 9.16989   20.44253 -24.85480 1.000 70.80961  ? 136 TYR   B CD2 1 
ATOM   3544 C  CE1 . TYR   B 1 139 ? 7.14596   18.74734 -24.06550 1.000 61.45647  ? 136 TYR   B CE1 1 
ATOM   3545 C  CE2 . TYR   B 1 139 ? 7.92760   20.95706 -24.54785 1.000 64.31888  ? 136 TYR   B CE2 1 
ATOM   3546 C  CZ  . TYR   B 1 139 ? 6.91925   20.11008 -24.15524 1.000 65.08776  ? 136 TYR   B CZ  1 
ATOM   3547 O  OH  . TYR   B 1 139 ? 5.68627   20.64321 -23.85547 1.000 68.39350  ? 136 TYR   B OH  1 
ATOM   3548 N  N   . TYR   B 1 140 ? 10.91034  16.82288 -27.68491 1.000 59.62342  ? 137 TYR   B N   1 
ATOM   3549 C  CA  . TYR   B 1 140 ? 10.38593  16.37207 -28.97046 1.000 57.62081  ? 137 TYR   B CA  1 
ATOM   3550 C  C   . TYR   B 1 140 ? 10.32103  14.85069 -29.04138 1.000 57.73146  ? 137 TYR   B C   1 
ATOM   3551 O  O   . TYR   B 1 140 ? 9.27288   14.27454 -29.35467 1.000 60.90072  ? 137 TYR   B O   1 
ATOM   3552 C  CB  . TYR   B 1 140 ? 11.25581  16.91439 -30.10199 1.000 58.34038  ? 137 TYR   B CB  1 
ATOM   3553 C  CG  . TYR   B 1 140 ? 11.01410  18.36123 -30.45844 1.000 59.30638  ? 137 TYR   B CG  1 
ATOM   3554 C  CD1 . TYR   B 1 140 ? 9.73285   18.83412 -30.70523 1.000 56.60846  ? 137 TYR   B CD1 1 
ATOM   3555 C  CD2 . TYR   B 1 140 ? 12.07408  19.25123 -30.57026 1.000 59.60450  ? 137 TYR   B CD2 1 
ATOM   3556 C  CE1 . TYR   B 1 140 ? 9.51416   20.15707 -31.04599 1.000 56.57159  ? 137 TYR   B CE1 1 
ATOM   3557 C  CE2 . TYR   B 1 140 ? 11.86546  20.57314 -30.90944 1.000 61.91817  ? 137 TYR   B CE2 1 
ATOM   3558 C  CZ  . TYR   B 1 140 ? 10.58451  21.02156 -31.14706 1.000 58.72657  ? 137 TYR   B CZ  1 
ATOM   3559 O  OH  . TYR   B 1 140 ? 10.37556  22.33941 -31.48727 1.000 62.49303  ? 137 TYR   B OH  1 
ATOM   3560 N  N   . ARG   B 1 141 ? 11.44188  14.18279 -28.75995 1.000 58.20586  ? 138 ARG   B N   1 
ATOM   3561 C  CA  . ARG   B 1 141 ? 11.47990  12.72655 -28.83826 1.000 58.12674  ? 138 ARG   B CA  1 
ATOM   3562 C  C   . ARG   B 1 141 ? 10.53548  12.07823 -27.83517 1.000 62.80035  ? 138 ARG   B C   1 
ATOM   3563 O  O   . ARG   B 1 141 ? 10.07584  10.95187 -28.05736 1.000 61.70644  ? 138 ARG   B O   1 
ATOM   3564 C  CB  . ARG   B 1 141 ? 12.91058  12.23680 -28.62904 1.000 60.03962  ? 138 ARG   B CB  1 
ATOM   3565 C  CG  . ARG   B 1 141 ? 13.84901  12.56879 -29.77550 1.000 55.12230  ? 138 ARG   B CG  1 
ATOM   3566 C  CD  . ARG   B 1 141 ? 15.27959  12.17194 -29.44667 1.000 81.37472  ? 138 ARG   B CD  1 
ATOM   3567 N  NE  . ARG   B 1 141 ? 15.38450  10.80923 -28.93823 1.000 89.59754  ? 138 ARG   B NE  1 
ATOM   3568 C  CZ  . ARG   B 1 141 ? 15.34770  9.71699  -29.68874 1.000 94.95044  ? 138 ARG   B CZ  1 
ATOM   3569 N  NH1 . ARG   B 1 141 ? 15.21238  9.78485  -31.00386 1.000 88.74697  ? 138 ARG   B NH1 1 
ATOM   3570 N  NH2 . ARG   B 1 141 ? 15.45304  8.52591  -29.10502 1.000 92.32655  ? 138 ARG   B NH2 1 
ATOM   3571 N  N   . ALA   B 1 142 ? 10.23519  12.76241 -26.72899 1.000 57.66581  ? 139 ALA   B N   1 
ATOM   3572 C  CA  . ALA   B 1 142 ? 9.25562   12.22704 -25.79054 1.000 60.43801  ? 139 ALA   B CA  1 
ATOM   3573 C  C   . ALA   B 1 142 ? 7.85509   12.26749 -26.38686 1.000 63.23168  ? 139 ALA   B C   1 
ATOM   3574 O  O   . ALA   B 1 142 ? 7.06783   11.33006 -26.20772 1.000 59.28423  ? 139 ALA   B O   1 
ATOM   3575 C  CB  . ALA   B 1 142 ? 9.30480   12.99837 -24.47136 1.000 55.96512  ? 139 ALA   B CB  1 
ATOM   3576 N  N   . ARG   B 1 143 ? 7.53263   13.34386 -27.10883 1.000 61.61060  ? 140 ARG   B N   1 
ATOM   3577 C  CA  . ARG   B 1 143 ? 6.22587   13.44674 -27.74738 1.000 59.09229  ? 140 ARG   B CA  1 
ATOM   3578 C  C   . ARG   B 1 143 ? 6.03842   12.37419 -28.81461 1.000 59.09691  ? 140 ARG   B C   1 
ATOM   3579 O  O   . ARG   B 1 143 ? 4.90736   11.94623 -29.07425 1.000 59.84446  ? 140 ARG   B O   1 
ATOM   3580 C  CB  . ARG   B 1 143 ? 6.04811   14.84659 -28.33653 1.000 55.77774  ? 140 ARG   B CB  1 
ATOM   3581 C  CG  . ARG   B 1 143 ? 4.60041   15.23033 -28.57629 1.000 74.54210  ? 140 ARG   B CG  1 
ATOM   3582 C  CD  . ARG   B 1 143 ? 4.46676   16.67797 -29.01982 1.000 79.21733  ? 140 ARG   B CD  1 
ATOM   3583 N  NE  . ARG   B 1 143 ? 3.91012   17.53813 -27.98103 1.000 65.89984  ? 140 ARG   B NE  1 
ATOM   3584 C  CZ  . ARG   B 1 143 ? 4.62989   18.33454 -27.20287 1.000 75.80707  ? 140 ARG   B CZ  1 
ATOM   3585 N  NH1 . ARG   B 1 143 ? 5.94835   18.39711 -27.30881 1.000 78.34713  ? 140 ARG   B NH1 1 
ATOM   3586 N  NH2 . ARG   B 1 143 ? 4.01052   19.09872 -26.30655 1.000 71.77340  ? 140 ARG   B NH2 1 
ATOM   3587 N  N   . ALA   B 1 144 ? 7.12574   11.92711 -29.43969 1.000 61.35995  ? 141 ALA   B N   1 
ATOM   3588 C  CA  . ALA   B 1 144 ? 7.05701   10.85041 -30.41929 1.000 58.44327  ? 141 ALA   B CA  1 
ATOM   3589 C  C   . ALA   B 1 144 ? 7.04525   9.46459  -29.78322 1.000 67.60766  ? 141 ALA   B C   1 
ATOM   3590 O  O   . ALA   B 1 144 ? 6.90834   8.47294  -30.50731 1.000 75.07707  ? 141 ALA   B O   1 
ATOM   3591 C  CB  . ALA   B 1 144 ? 8.22478   10.95709 -31.40314 1.000 52.30441  ? 141 ALA   B CB  1 
ATOM   3592 N  N   . GLY   B 1 145 ? 7.18608   9.36837  -28.46084 1.000 63.89362  ? 142 GLY   B N   1 
ATOM   3593 C  CA  . GLY   B 1 145 ? 7.12266   8.10066  -27.75878 1.000 66.72962  ? 142 GLY   B CA  1 
ATOM   3594 C  C   . GLY   B 1 145 ? 8.43184   7.59147  -27.18850 1.000 67.20761  ? 142 GLY   B C   1 
ATOM   3595 O  O   . GLY   B 1 145 ? 8.42562   6.54914  -26.52219 1.000 59.12143  ? 142 GLY   B O   1 
ATOM   3596 N  N   . GLU   B 1 146 ? 9.54933   8.27625  -27.41742 1.000 66.45477  ? 143 GLU   B N   1 
ATOM   3597 C  CA  . GLU   B 1 146 ? 10.84742  7.88384  -26.86774 1.000 68.67580  ? 143 GLU   B CA  1 
ATOM   3598 C  C   . GLU   B 1 146 ? 11.21036  8.86162  -25.75015 1.000 66.65199  ? 143 GLU   B C   1 
ATOM   3599 O  O   . GLU   B 1 146 ? 12.06108  9.73859  -25.90944 1.000 68.49045  ? 143 GLU   B O   1 
ATOM   3600 C  CB  . GLU   B 1 146 ? 11.91468  7.83698  -27.96369 1.000 73.29711  ? 143 GLU   B CB  1 
ATOM   3601 C  CG  . GLU   B 1 146 ? 11.71762  6.70004  -28.95620 1.000 80.60996  ? 143 GLU   B CG  1 
ATOM   3602 C  CD  . GLU   B 1 146 ? 12.24809  7.02518  -30.33954 1.000 102.94642 ? 143 GLU   B CD  1 
ATOM   3603 O  OE1 . GLU   B 1 146 ? 12.93339  8.05860  -30.48779 1.000 97.01310  ? 143 GLU   B OE1 1 
ATOM   3604 O  OE2 . GLU   B 1 146 ? 11.98289  6.24493  -31.27927 1.000 108.81808 ? 143 GLU   B OE2 1 
ATOM   3605 N  N   . ALA   B 1 147 ? 10.55478  8.69566  -24.60212 1.000 64.36644  ? 144 ALA   B N   1 
ATOM   3606 C  CA  . ALA   B 1 147 ? 10.62395  9.64559  -23.50002 1.000 64.56257  ? 144 ALA   B CA  1 
ATOM   3607 C  C   . ALA   B 1 147 ? 11.69071  9.29915  -22.46531 1.000 66.77860  ? 144 ALA   B C   1 
ATOM   3608 O  O   . ALA   B 1 147 ? 11.74397  9.94770  -21.41387 1.000 63.61167  ? 144 ALA   B O   1 
ATOM   3609 C  CB  . ALA   B 1 147 ? 9.25911   9.74789  -22.81308 1.000 62.92901  ? 144 ALA   B CB  1 
ATOM   3610 N  N   . ALA   B 1 148 ? 12.52995  8.29313  -22.72792 1.000 65.00619  ? 145 ALA   B N   1 
ATOM   3611 C  CA  . ALA   B 1 148 ? 13.50749  7.86394  -21.73007 1.000 63.86750  ? 145 ALA   B CA  1 
ATOM   3612 C  C   . ALA   B 1 148 ? 14.48535  8.98346  -21.39081 1.000 67.66755  ? 145 ALA   B C   1 
ATOM   3613 O  O   . ALA   B 1 148 ? 14.67902  9.31847  -20.21574 1.000 67.78063  ? 145 ALA   B O   1 
ATOM   3614 C  CB  . ALA   B 1 148 ? 14.25422  6.62463  -22.22049 1.000 62.08266  ? 145 ALA   B CB  1 
ATOM   3615 N  N   . ASN   B 1 149 ? 15.11737  9.57316  -22.40944 1.000 59.96692  ? 146 ASN   B N   1 
ATOM   3616 C  CA  . ASN   B 1 149 ? 16.07328  10.64712 -22.15377 1.000 57.47891  ? 146 ASN   B CA  1 
ATOM   3617 C  C   . ASN   B 1 149 ? 15.40136  11.84442 -21.49420 1.000 62.13203  ? 146 ASN   B C   1 
ATOM   3618 O  O   . ASN   B 1 149 ? 16.00644  12.51630 -20.65097 1.000 68.04239  ? 146 ASN   B O   1 
ATOM   3619 C  CB  . ASN   B 1 149 ? 16.76242  11.06277 -23.45060 1.000 55.62593  ? 146 ASN   B CB  1 
ATOM   3620 C  CG  . ASN   B 1 149 ? 17.68713  9.98995  -23.98159 1.000 69.44425  ? 146 ASN   B CG  1 
ATOM   3621 O  OD1 . ASN   B 1 149 ? 17.25209  9.05940  -24.65888 1.000 80.40199  ? 146 ASN   B OD1 1 
ATOM   3622 N  ND2 . ASN   B 1 149 ? 18.97183  10.10682 -23.66560 1.000 74.46531  ? 146 ASN   B ND2 1 
ATOM   3623 N  N   . PHE   B 1 150 ? 14.15445  12.13313 -21.86908 1.000 64.81360  ? 147 PHE   B N   1 
ATOM   3624 C  CA  . PHE   B 1 150 ? 13.44812  13.25904 -21.26742 1.000 58.67903  ? 147 PHE   B CA  1 
ATOM   3625 C  C   . PHE   B 1 150 ? 13.21963  13.02561 -19.78034 1.000 62.35556  ? 147 PHE   B C   1 
ATOM   3626 O  O   . PHE   B 1 150 ? 13.46883  13.91302 -18.95643 1.000 62.14185  ? 147 PHE   B O   1 
ATOM   3627 C  CB  . PHE   B 1 150 ? 12.12416  13.49848 -21.99134 1.000 58.94607  ? 147 PHE   B CB  1 
ATOM   3628 C  CG  . PHE   B 1 150 ? 11.45938  14.79355 -21.62386 1.000 49.48492  ? 147 PHE   B CG  1 
ATOM   3629 C  CD1 . PHE   B 1 150 ? 12.14559  15.99381 -21.72890 1.000 49.17096  ? 147 PHE   B CD1 1 
ATOM   3630 C  CD2 . PHE   B 1 150 ? 10.14614  14.81326 -21.18722 1.000 46.18982  ? 147 PHE   B CD2 1 
ATOM   3631 C  CE1 . PHE   B 1 150 ? 11.53490  17.19095 -21.39524 1.000 48.55040  ? 147 PHE   B CE1 1 
ATOM   3632 C  CE2 . PHE   B 1 150 ? 9.52927   16.00546 -20.85473 1.000 51.21374  ? 147 PHE   B CE2 1 
ATOM   3633 C  CZ  . PHE   B 1 150 ? 10.22499  17.19574 -20.95732 1.000 48.87438  ? 147 PHE   B CZ  1 
ATOM   3634 N  N   . CYS   B 1 151 ? 12.74495  11.83082 -19.41761 1.000 62.93157  ? 148 CYS   B N   1 
ATOM   3635 C  CA  . CYS   B 1 151 ? 12.53702  11.51950 -18.00695 1.000 62.30109  ? 148 CYS   B CA  1 
ATOM   3636 C  C   . CYS   B 1 151 ? 13.84650  11.56735 -17.23415 1.000 63.58303  ? 148 CYS   B C   1 
ATOM   3637 O  O   . CYS   B 1 151 ? 13.89618  12.08587 -16.11227 1.000 65.01666  ? 148 CYS   B O   1 
ATOM   3638 C  CB  . CYS   B 1 151 ? 11.88913  10.14372 -17.85611 1.000 62.01733  ? 148 CYS   B CB  1 
ATOM   3639 S  SG  . CYS   B 1 151 ? 10.25381  9.99974  -18.59069 1.000 68.24870  ? 148 CYS   B SG  1 
ATOM   3640 N  N   . ALA   B 1 152 ? 14.92049  11.03465 -17.82039 1.000 60.53427  ? 149 ALA   B N   1 
ATOM   3641 C  CA  . ALA   B 1 152 ? 16.21556  11.06184 -17.15052 1.000 58.92447  ? 149 ALA   B CA  1 
ATOM   3642 C  C   . ALA   B 1 152 ? 16.70784  12.49087 -16.95022 1.000 64.36584  ? 149 ALA   B C   1 
ATOM   3643 O  O   . ALA   B 1 152 ? 17.23961  12.82724 -15.88523 1.000 71.49786  ? 149 ALA   B O   1 
ATOM   3644 C  CB  . ALA   B 1 152 ? 17.23170  10.24590 -17.94670 1.000 56.93866  ? 149 ALA   B CB  1 
ATOM   3645 N  N   . LEU   B 1 153 ? 16.53980  13.34717 -17.96254 1.000 61.03145  ? 150 LEU   B N   1 
ATOM   3646 C  CA  . LEU   B 1 153 ? 16.95897  14.73854 -17.82715 1.000 56.72449  ? 150 LEU   B CA  1 
ATOM   3647 C  C   . LEU   B 1 153 ? 16.10037  15.47646 -16.80910 1.000 61.32301  ? 150 LEU   B C   1 
ATOM   3648 O  O   . LEU   B 1 153 ? 16.60422  16.32562 -16.06539 1.000 60.23468  ? 150 LEU   B O   1 
ATOM   3649 C  CB  . LEU   B 1 153 ? 16.91323  15.44001 -19.18330 1.000 59.61023  ? 150 LEU   B CB  1 
ATOM   3650 C  CG  . LEU   B 1 153 ? 18.04032  15.04913 -20.13992 1.000 64.36478  ? 150 LEU   B CG  1 
ATOM   3651 C  CD1 . LEU   B 1 153 ? 17.81087  15.63002 -21.52355 1.000 57.94968  ? 150 LEU   B CD1 1 
ATOM   3652 C  CD2 . LEU   B 1 153 ? 19.38023  15.50071 -19.58590 1.000 61.83778  ? 150 LEU   B CD2 1 
ATOM   3653 N  N   . ILE   B 1 154 ? 14.80188  15.17101 -16.76181 1.000 61.09714  ? 151 ILE   B N   1 
ATOM   3654 C  CA  . ILE   B 1 154 ? 13.93717  15.78763 -15.76101 1.000 58.58854  ? 151 ILE   B CA  1 
ATOM   3655 C  C   . ILE   B 1 154 ? 14.44885  15.47787 -14.36188 1.000 68.00753  ? 151 ILE   B C   1 
ATOM   3656 O  O   . ILE   B 1 154 ? 14.51823  16.36205 -13.49858 1.000 65.80492  ? 151 ILE   B O   1 
ATOM   3657 C  CB  . ILE   B 1 154 ? 12.48212  15.32085 -15.94608 1.000 59.12572  ? 151 ILE   B CB  1 
ATOM   3658 C  CG1 . ILE   B 1 154 ? 11.87757  15.93369 -17.20702 1.000 63.09941  ? 151 ILE   B CG1 1 
ATOM   3659 C  CG2 . ILE   B 1 154 ? 11.64456  15.68666 -14.73111 1.000 59.19148  ? 151 ILE   B CG2 1 
ATOM   3660 C  CD1 . ILE   B 1 154 ? 10.49252  15.42651 -17.50981 1.000 53.75942  ? 151 ILE   B CD1 1 
ATOM   3661 N  N   . LEU   B 1 155 ? 14.82555  14.21822 -14.12029 1.000 64.76476  ? 152 LEU   B N   1 
ATOM   3662 C  CA  . LEU   B 1 155 ? 15.35829  13.83402 -12.81622 1.000 65.18039  ? 152 LEU   B CA  1 
ATOM   3663 C  C   . LEU   B 1 155 ? 16.66376  14.55723 -12.51096 1.000 68.13046  ? 152 LEU   B C   1 
ATOM   3664 O  O   . LEU   B 1 155 ? 16.86988  15.03062 -11.38688 1.000 68.69896  ? 152 LEU   B O   1 
ATOM   3665 C  CB  . LEU   B 1 155 ? 15.55974  12.31946 -12.75926 1.000 62.78533  ? 152 LEU   B CB  1 
ATOM   3666 C  CG  . LEU   B 1 155 ? 14.28466  11.47385 -12.76295 1.000 62.47353  ? 152 LEU   B CG  1 
ATOM   3667 C  CD1 . LEU   B 1 155 ? 14.60625  9.99782  -12.92302 1.000 56.68666  ? 152 LEU   B CD1 1 
ATOM   3668 C  CD2 . LEU   B 1 155 ? 13.48096  11.71216 -11.50025 1.000 53.68760  ? 152 LEU   B CD2 1 
ATOM   3669 N  N   . ALA   B 1 156 ? 17.55405  14.65999 -13.50027 1.000 60.02594  ? 153 ALA   B N   1 
ATOM   3670 C  CA  . ALA   B 1 156 ? 18.84700  15.29753 -13.27178 1.000 54.91376  ? 153 ALA   B CA  1 
ATOM   3671 C  C   . ALA   B 1 156 ? 18.68823  16.78207 -12.95728 1.000 58.91417  ? 153 ALA   B C   1 
ATOM   3672 O  O   . ALA   B 1 156 ? 19.29307  17.29239 -12.00812 1.000 66.40303  ? 153 ALA   B O   1 
ATOM   3673 C  CB  . ALA   B 1 156 ? 19.75329  15.09252 -14.48462 1.000 56.49900  ? 153 ALA   B CB  1 
ATOM   3674 N  N   . TYR   B 1 157 ? 17.87139  17.49260 -13.73807 1.000 66.67360  ? 154 TYR   B N   1 
ATOM   3675 C  CA  . TYR   B 1 157 ? 17.69046  18.92270 -13.51123 1.000 70.59021  ? 154 TYR   B CA  1 
ATOM   3676 C  C   . TYR   B 1 157 ? 16.98680  19.22680 -12.19412 1.000 71.92775  ? 154 TYR   B C   1 
ATOM   3677 O  O   . TYR   B 1 157 ? 17.13211  20.33709 -11.67094 1.000 76.39284  ? 154 TYR   B O   1 
ATOM   3678 C  CB  . TYR   B 1 157 ? 16.91184  19.55028 -14.67090 1.000 62.10763  ? 154 TYR   B CB  1 
ATOM   3679 C  CG  . TYR   B 1 157 ? 17.74842  19.81046 -15.90595 1.000 64.22901  ? 154 TYR   B CG  1 
ATOM   3680 C  CD1 . TYR   B 1 157 ? 18.67625  20.84215 -15.93486 1.000 60.19130  ? 154 TYR   B CD1 1 
ATOM   3681 C  CD2 . TYR   B 1 157 ? 17.60389  19.02836 -17.04601 1.000 63.67028  ? 154 TYR   B CD2 1 
ATOM   3682 C  CE1 . TYR   B 1 157 ? 19.44126  21.08450 -17.06024 1.000 63.70141  ? 154 TYR   B CE1 1 
ATOM   3683 C  CE2 . TYR   B 1 157 ? 18.36411  19.26276 -18.17767 1.000 57.57625  ? 154 TYR   B CE2 1 
ATOM   3684 C  CZ  . TYR   B 1 157 ? 19.28013  20.29112 -18.17931 1.000 60.58917  ? 154 TYR   B CZ  1 
ATOM   3685 O  OH  . TYR   B 1 157 ? 20.03716  20.52473 -19.30426 1.000 65.81481  ? 154 TYR   B OH  1 
ATOM   3686 N  N   . CYS   B 1 158 ? 16.24009  18.27496 -11.64308 1.000 73.13912  ? 155 CYS   B N   1 
ATOM   3687 C  CA  . CYS   B 1 158 ? 15.50453  18.48873 -10.40482 1.000 80.29519  ? 155 CYS   B CA  1 
ATOM   3688 C  C   . CYS   B 1 158 ? 16.22247  17.94556 -9.18195  1.000 82.34953  ? 155 CYS   B C   1 
ATOM   3689 O  O   . CYS   B 1 158 ? 15.68539  18.04565 -8.07438  1.000 88.18862  ? 155 CYS   B O   1 
ATOM   3690 C  CB  . CYS   B 1 158 ? 14.11430  17.85912 -10.49487 1.000 68.53703  ? 155 CYS   B CB  1 
ATOM   3691 S  SG  . CYS   B 1 158 ? 13.04069  18.67462 -11.67172 1.000 72.57311  ? 155 CYS   B SG  1 
ATOM   3692 N  N   . ASN   B 1 159 ? 17.41264  17.37139 -9.35709  1.000 83.82193  ? 156 ASN   B N   1 
ATOM   3693 C  CA  . ASN   B 1 159 ? 18.16222  16.74903 -8.26637  1.000 77.47989  ? 156 ASN   B CA  1 
ATOM   3694 C  C   . ASN   B 1 159 ? 17.32513  15.68410 -7.56139  1.000 77.74940  ? 156 ASN   B C   1 
ATOM   3695 O  O   . ASN   B 1 159 ? 17.28761  15.60718 -6.33189  1.000 87.67364  ? 156 ASN   B O   1 
ATOM   3696 C  CB  . ASN   B 1 159 ? 18.66810  17.79772 -7.27577  1.000 73.22366  ? 156 ASN   B CB  1 
ATOM   3697 C  CG  . ASN   B 1 159 ? 19.78658  18.64012 -7.84877  1.000 89.53969  ? 156 ASN   B CG  1 
ATOM   3698 O  OD1 . ASN   B 1 159 ? 20.91248  18.16955 -8.01317  1.000 96.78101  ? 156 ASN   B OD1 1 
ATOM   3699 N  ND2 . ASN   B 1 159 ? 19.48081  19.89443 -8.16227  1.000 90.09476  ? 156 ASN   B ND2 1 
ATOM   3700 N  N   . LYS   B 1 160 ? 16.63900  14.86440 -8.35406  1.000 73.51943  ? 157 LYS   B N   1 
ATOM   3701 C  CA  . LYS   B 1 160 ? 15.91279  13.69907 -7.87585  1.000 72.00517  ? 157 LYS   B CA  1 
ATOM   3702 C  C   . LYS   B 1 160 ? 16.50512  12.44611 -8.50724  1.000 65.79953  ? 157 LYS   B C   1 
ATOM   3703 O  O   . LYS   B 1 160 ? 17.12438  12.49352 -9.57306  1.000 64.18798  ? 157 LYS   B O   1 
ATOM   3704 C  CB  . LYS   B 1 160 ? 14.40921  13.79196 -8.19191  1.000 65.58473  ? 157 LYS   B CB  1 
ATOM   3705 C  CG  . LYS   B 1 160 ? 13.68131  14.97083 -7.54723  1.000 72.84997  ? 157 LYS   B CG  1 
ATOM   3706 C  CD  . LYS   B 1 160 ? 13.32900  14.65979 -6.09552  1.000 87.14440  ? 157 LYS   B CD  1 
ATOM   3707 C  CE  . LYS   B 1 160 ? 12.58497  15.80466 -5.41386  1.000 98.42511  ? 157 LYS   B CE  1 
ATOM   3708 N  NZ  . LYS   B 1 160 ? 11.15037  15.88982 -5.81608  1.000 96.66942  ? 157 LYS   B NZ  1 
ATOM   3709 N  N   . THR   B 1 161 ? 16.32244  11.32044 -7.82732  1.000 65.12891  ? 158 THR   B N   1 
ATOM   3710 C  CA  . THR   B 1 161 ? 16.84781  10.04355 -8.27890  1.000 66.49898  ? 158 THR   B CA  1 
ATOM   3711 C  C   . THR   B 1 161 ? 15.70360  9.07334  -8.53814  1.000 68.82811  ? 158 THR   B C   1 
ATOM   3712 O  O   . THR   B 1 161 ? 14.58140  9.25724  -8.05640  1.000 71.06416  ? 158 THR   B O   1 
ATOM   3713 C  CB  . THR   B 1 161 ? 17.81495  9.44164  -7.24890  1.000 75.41861  ? 158 THR   B CB  1 
ATOM   3714 O  OG1 . THR   B 1 161 ? 17.08786  9.07430  -6.06995  1.000 83.19459  ? 158 THR   B OG1 1 
ATOM   3715 C  CG2 . THR   B 1 161 ? 18.89663  10.44682 -6.87469  1.000 67.45455  ? 158 THR   B CG2 1 
ATOM   3716 N  N   . VAL   B 1 162 ? 16.00335  8.03329  -9.31919  1.000 67.22821  ? 159 VAL   B N   1 
ATOM   3717 C  CA  . VAL   B 1 162 ? 15.01130  7.00386  -9.59837  1.000 67.28785  ? 159 VAL   B CA  1 
ATOM   3718 C  C   . VAL   B 1 162 ? 14.57577  6.35421  -8.29392  1.000 74.21020  ? 159 VAL   B C   1 
ATOM   3719 O  O   . VAL   B 1 162 ? 15.40725  5.92106  -7.48617  1.000 80.53284  ? 159 VAL   B O   1 
ATOM   3720 C  CB  . VAL   B 1 162 ? 15.58240  5.97072  -10.57838 1.000 64.61291  ? 159 VAL   B CB  1 
ATOM   3721 C  CG1 . VAL   B 1 162 ? 14.60045  4.84022  -10.78222 1.000 70.30935  ? 159 VAL   B CG1 1 
ATOM   3722 C  CG2 . VAL   B 1 162 ? 15.91621  6.63201  -11.90134 1.000 69.87135  ? 159 VAL   B CG2 1 
ATOM   3723 N  N   . GLY   B 1 163 ? 13.26453  6.28929  -8.07957  1.000 71.99671  ? 160 GLY   B N   1 
ATOM   3724 C  CA  . GLY   B 1 163 ? 12.72984  5.70667  -6.86613  1.000 58.41105  ? 160 GLY   B CA  1 
ATOM   3725 C  C   . GLY   B 1 163 ? 12.24142  6.76322  -5.89916  1.000 64.84728  ? 160 GLY   B C   1 
ATOM   3726 O  O   . GLY   B 1 163 ? 11.23602  6.57246  -5.20718  1.000 68.29635  ? 160 GLY   B O   1 
ATOM   3727 N  N   . GLU   B 1 164 ? 12.95967  7.88309  -5.84092  1.000 67.18380  ? 161 GLU   B N   1 
ATOM   3728 C  CA  . GLU   B 1 164 ? 12.59463  8.96258  -4.93484  1.000 69.32515  ? 161 GLU   B CA  1 
ATOM   3729 C  C   . GLU   B 1 164 ? 11.22475  9.51839  -5.30391  1.000 68.43136  ? 161 GLU   B C   1 
ATOM   3730 O  O   . GLU   B 1 164 ? 10.92203  9.74583  -6.47843  1.000 83.45290  ? 161 GLU   B O   1 
ATOM   3731 C  CB  . GLU   B 1 164 ? 13.66196  10.06031 -4.98781  1.000 64.28408  ? 161 GLU   B CB  1 
ATOM   3732 C  CG  . GLU   B 1 164 ? 13.41634  11.26501 -4.09290  1.000 73.56656  ? 161 GLU   B CG  1 
ATOM   3733 C  CD  . GLU   B 1 164 ? 14.62062  12.19380 -4.03777  1.000 79.37318  ? 161 GLU   B CD  1 
ATOM   3734 O  OE1 . GLU   B 1 164 ? 15.67995  11.82238 -4.58643  1.000 78.82828  ? 161 GLU   B OE1 1 
ATOM   3735 O  OE2 . GLU   B 1 164 ? 14.51209  13.29173 -3.44842  1.000 79.51085  ? 161 GLU   B OE2 1 
ATOM   3736 N  N   . LEU   B 1 165 ? 10.39353  9.73667  -4.28959  1.000 70.20874  ? 162 LEU   B N   1 
ATOM   3737 C  CA  . LEU   B 1 165 ? 9.09412   10.34932 -4.50894  1.000 69.16975  ? 162 LEU   B CA  1 
ATOM   3738 C  C   . LEU   B 1 165 ? 9.25046   11.83413 -4.82208  1.000 75.82279  ? 162 LEU   B C   1 
ATOM   3739 O  O   . LEU   B 1 165 ? 10.26131  12.46364 -4.49670  1.000 78.50038  ? 162 LEU   B O   1 
ATOM   3740 C  CB  . LEU   B 1 165 ? 8.19714   10.15063 -3.28840  1.000 71.47486  ? 162 LEU   B CB  1 
ATOM   3741 C  CG  . LEU   B 1 165 ? 8.05555   8.70323  -2.80478  1.000 73.74649  ? 162 LEU   B CG  1 
ATOM   3742 C  CD1 . LEU   B 1 165 ? 6.98042   8.59988  -1.73516  1.000 76.01175  ? 162 LEU   B CD1 1 
ATOM   3743 C  CD2 . LEU   B 1 165 ? 7.76740   7.74527  -3.96086  1.000 76.29875  ? 162 LEU   B CD2 1 
ATOM   3744 N  N   . GLY   B 1 166 ? 8.22777   12.39579 -5.46226  1.000 72.98007  ? 163 GLY   B N   1 
ATOM   3745 C  CA  . GLY   B 1 166 ? 8.29507   13.77772 -5.89770  1.000 65.58723  ? 163 GLY   B CA  1 
ATOM   3746 C  C   . GLY   B 1 166 ? 6.93550   14.43939 -5.92488  1.000 66.46449  ? 163 GLY   B C   1 
ATOM   3747 O  O   . GLY   B 1 166 ? 5.89167   13.77828 -5.89410  1.000 65.60562  ? 163 GLY   B O   1 
ATOM   3748 N  N   . ASP   B 1 167 ? 6.96823   15.76900 -5.97657  1.000 63.47486  ? 164 ASP   B N   1 
ATOM   3749 C  CA  . ASP   B 1 167 ? 5.77732   16.59730 -6.10718  1.000 70.24524  ? 164 ASP   B CA  1 
ATOM   3750 C  C   . ASP   B 1 167 ? 5.70607   17.11218 -7.54082  1.000 75.04315  ? 164 ASP   B C   1 
ATOM   3751 O  O   . ASP   B 1 167 ? 6.70541   17.60295 -8.07797  1.000 72.23239  ? 164 ASP   B O   1 
ATOM   3752 C  CB  . ASP   B 1 167 ? 5.81732   17.76099 -5.11086  1.000 62.07885  ? 164 ASP   B CB  1 
ATOM   3753 C  CG  . ASP   B 1 167 ? 4.53184   18.58778 -5.09833  1.000 80.00718  ? 164 ASP   B CG  1 
ATOM   3754 O  OD1 . ASP   B 1 167 ? 3.94034   18.82634 -6.17270  1.000 94.83392  ? 164 ASP   B OD1 1 
ATOM   3755 O  OD2 . ASP   B 1 167 ? 4.11504   19.01929 -4.00082  1.000 83.85983  ? 164 ASP   B OD2 1 
ATOM   3756 N  N   . VAL   B 1 168 ? 4.52565   17.00353 -8.15558  1.000 70.39268  ? 165 VAL   B N   1 
ATOM   3757 C  CA  . VAL   B 1 168 ? 4.37482   17.45273 -9.53747  1.000 70.93752  ? 165 VAL   B CA  1 
ATOM   3758 C  C   . VAL   B 1 168 ? 4.56214   18.96305 -9.62898  1.000 68.30526  ? 165 VAL   B C   1 
ATOM   3759 O  O   . VAL   B 1 168 ? 5.17857   19.46992 -10.57433 1.000 71.07112  ? 165 VAL   B O   1 
ATOM   3760 C  CB  . VAL   B 1 168 ? 3.01238   17.00566 -10.10189 1.000 66.70234  ? 165 VAL   B CB  1 
ATOM   3761 C  CG1 . VAL   B 1 168 ? 2.68839   17.74851 -11.38811 1.000 64.99476  ? 165 VAL   B CG1 1 
ATOM   3762 C  CG2 . VAL   B 1 168 ? 3.01087   15.50344 -10.35090 1.000 53.63872  ? 165 VAL   B CG2 1 
ATOM   3763 N  N   . ARG   B 1 169 ? 4.05974   19.70356 -8.63749  1.000 66.77688  ? 166 ARG   B N   1 
ATOM   3764 C  CA  . ARG   B 1 169 ? 4.17642   21.15866 -8.66329  1.000 68.14666  ? 166 ARG   B CA  1 
ATOM   3765 C  C   . ARG   B 1 169 ? 5.63013   21.60504 -8.56962  1.000 74.00570  ? 166 ARG   B C   1 
ATOM   3766 O  O   . ARG   B 1 169 ? 6.04116   22.54834 -9.25645  1.000 74.83935  ? 166 ARG   B O   1 
ATOM   3767 C  CB  . ARG   B 1 169 ? 3.36843   21.76820 -7.52193  1.000 65.09219  ? 166 ARG   B CB  1 
ATOM   3768 C  CG  . ARG   B 1 169 ? 3.46087   23.27827 -7.44564  1.000 73.79887  ? 166 ARG   B CG  1 
ATOM   3769 C  CD  . ARG   B 1 169 ? 2.86520   23.77090 -6.14855  1.000 87.98091  ? 166 ARG   B CD  1 
ATOM   3770 N  NE  . ARG   B 1 169 ? 3.45745   23.05984 -5.02247  1.000 91.00666  ? 166 ARG   B NE  1 
ATOM   3771 C  CZ  . ARG   B 1 169 ? 4.56351   23.43754 -4.39760  1.000 92.83471  ? 166 ARG   B CZ  1 
ATOM   3772 N  NH1 . ARG   B 1 169 ? 5.22105   24.52852 -4.75637  1.000 85.86759  ? 166 ARG   B NH1 1 
ATOM   3773 N  NH2 . ARG   B 1 169 ? 5.02609   22.69747 -3.39360  1.000 97.65978  ? 166 ARG   B NH2 1 
ATOM   3774 N  N   . GLU   B 1 170 ? 6.42089   20.94799 -7.71732  1.000 77.21896  ? 167 GLU   B N   1 
ATOM   3775 C  CA  . GLU   B 1 170 ? 7.83519   21.29127 -7.61286  1.000 68.36866  ? 167 GLU   B CA  1 
ATOM   3776 C  C   . GLU   B 1 170 ? 8.57819   20.96206 -8.89928  1.000 73.80929  ? 167 GLU   B C   1 
ATOM   3777 O  O   . GLU   B 1 170 ? 9.47918   21.70348 -9.30904  1.000 76.99968  ? 167 GLU   B O   1 
ATOM   3778 C  CB  . GLU   B 1 170 ? 8.46904   20.55998 -6.43097  1.000 81.01891  ? 167 GLU   B CB  1 
ATOM   3779 C  CG  . GLU   B 1 170 ? 7.80733   20.83448 -5.09042  1.000 95.55339  ? 167 GLU   B CG  1 
ATOM   3780 C  CD  . GLU   B 1 170 ? 8.45519   20.06192 -3.95581  1.000 98.42632  ? 167 GLU   B CD  1 
ATOM   3781 O  OE1 . GLU   B 1 170 ? 9.42230   19.31470 -4.22149  1.000 97.43941  ? 167 GLU   B OE1 1 
ATOM   3782 O  OE2 . GLU   B 1 170 ? 7.99399   20.19776 -2.80144  1.000 88.97086  ? 167 GLU   B OE2 1 
ATOM   3783 N  N   . THR   B 1 171 ? 8.20864   19.85841 -9.55293  1.000 73.00653  ? 168 THR   B N   1 
ATOM   3784 C  CA  . THR   B 1 171 ? 8.85431   19.48445 -10.80784 1.000 68.53440  ? 168 THR   B CA  1 
ATOM   3785 C  C   . THR   B 1 171 ? 8.56560   20.50874 -11.89917 1.000 70.26305  ? 168 THR   B C   1 
ATOM   3786 O  O   . THR   B 1 171 ? 9.47854   20.94172 -12.61334 1.000 72.51176  ? 168 THR   B O   1 
ATOM   3787 C  CB  . THR   B 1 171 ? 8.39692   18.09081 -11.23936 1.000 65.02053  ? 168 THR   B CB  1 
ATOM   3788 O  OG1 . THR   B 1 171 ? 8.63261   17.15988 -10.17635 1.000 59.83918  ? 168 THR   B OG1 1 
ATOM   3789 C  CG2 . THR   B 1 171 ? 9.15545   17.63803 -12.47699 1.000 61.47554  ? 168 THR   B CG2 1 
ATOM   3790 N  N   . MET   B 1 172 ? 7.29806   20.90288 -12.04708 1.000 66.40359  ? 169 MET   B N   1 
ATOM   3791 C  CA  . MET   B 1 172 ? 6.95619   21.93984 -13.01635 1.000 71.45462  ? 169 MET   B CA  1 
ATOM   3792 C  C   . MET   B 1 172 ? 7.72109   23.22723 -12.74053 1.000 75.19672  ? 169 MET   B C   1 
ATOM   3793 O  O   . MET   B 1 172 ? 8.19858   23.88405 -13.67305 1.000 71.60190  ? 169 MET   B O   1 
ATOM   3794 C  CB  . MET   B 1 172 ? 5.44869   22.20202 -12.99765 1.000 74.09297  ? 169 MET   B CB  1 
ATOM   3795 C  CG  . MET   B 1 172 ? 4.55696   21.03156 -13.41760 1.000 73.39667  ? 169 MET   B CG  1 
ATOM   3796 S  SD  . MET   B 1 172 ? 4.71912   20.53168 -15.14902 1.000 79.52326  ? 169 MET   B SD  1 
ATOM   3797 C  CE  . MET   B 1 172 ? 5.90525   19.20308 -15.01550 1.000 61.30027  ? 169 MET   B CE  1 
ATOM   3798 N  N   . SER   B 1 173 ? 7.86209   23.59212 -11.46276 1.000 77.63631  ? 170 SER   B N   1 
ATOM   3799 C  CA  . SER   B 1 173 ? 8.54585   24.83275 -11.10943 1.000 71.23912  ? 170 SER   B CA  1 
ATOM   3800 C  C   . SER   B 1 173 ? 10.00729  24.80869 -11.54504 1.000 76.99370  ? 170 SER   B C   1 
ATOM   3801 O  O   . SER   B 1 173 ? 10.51164  25.79333 -12.09866 1.000 77.54119  ? 170 SER   B O   1 
ATOM   3802 C  CB  . SER   B 1 173 ? 8.43391   25.08086 -9.60657  1.000 79.03999  ? 170 SER   B CB  1 
ATOM   3803 O  OG  . SER   B 1 173 ? 9.15368   26.24181 -9.23142  1.000 94.91666  ? 170 SER   B OG  1 
ATOM   3804 N  N   . TYR   B 1 174 ? 10.70740  23.69695 -11.29460 1.000 75.78040  ? 171 TYR   B N   1 
ATOM   3805 C  CA  . TYR   B 1 174 ? 12.09335  23.57461 -11.74111 1.000 73.71049  ? 171 TYR   B CA  1 
ATOM   3806 C  C   . TYR   B 1 174 ? 12.19508  23.66213 -13.25850 1.000 77.41950  ? 171 TYR   B C   1 
ATOM   3807 O  O   . TYR   B 1 174 ? 13.05638  24.36894 -13.79617 1.000 77.85409  ? 171 TYR   B O   1 
ATOM   3808 C  CB  . TYR   B 1 174 ? 12.69471  22.25807 -11.24744 1.000 70.91217  ? 171 TYR   B CB  1 
ATOM   3809 C  CG  . TYR   B 1 174 ? 13.48024  22.35994 -9.96187  1.000 96.32049  ? 171 TYR   B CG  1 
ATOM   3810 C  CD1 . TYR   B 1 174 ? 14.66914  23.07745 -9.91176  1.000 100.58680 ? 171 TYR   B CD1 1 
ATOM   3811 C  CD2 . TYR   B 1 174 ? 13.04689  21.72630 -8.80257  1.000 103.05337 ? 171 TYR   B CD2 1 
ATOM   3812 C  CE1 . TYR   B 1 174 ? 15.40208  23.16959 -8.74131  1.000 108.22016 ? 171 TYR   B CE1 1 
ATOM   3813 C  CE2 . TYR   B 1 174 ? 13.77304  21.81374 -7.62586  1.000 103.42179 ? 171 TYR   B CE2 1 
ATOM   3814 C  CZ  . TYR   B 1 174 ? 14.94901  22.53631 -7.60132  1.000 113.59909 ? 171 TYR   B CZ  1 
ATOM   3815 O  OH  . TYR   B 1 174 ? 15.67269  22.62448 -6.43278  1.000 117.11363 ? 171 TYR   B OH  1 
ATOM   3816 N  N   . LEU   B 1 175 ? 11.31685  22.95070 -13.96740 1.000 70.57796  ? 172 LEU   B N   1 
ATOM   3817 C  CA  . LEU   B 1 175 ? 11.37807  22.94830 -15.42473 1.000 67.80306  ? 172 LEU   B CA  1 
ATOM   3818 C  C   . LEU   B 1 175 ? 11.06932  24.32729 -15.99554 1.000 63.79667  ? 172 LEU   B C   1 
ATOM   3819 O  O   . LEU   B 1 175 ? 11.67064  24.73959 -16.99456 1.000 70.48481  ? 172 LEU   B O   1 
ATOM   3820 C  CB  . LEU   B 1 175 ? 10.42059  21.89584 -15.98422 1.000 68.45460  ? 172 LEU   B CB  1 
ATOM   3821 C  CG  . LEU   B 1 175 ? 10.74250  20.45152 -15.58397 1.000 63.89836  ? 172 LEU   B CG  1 
ATOM   3822 C  CD1 . LEU   B 1 175 ? 9.73056   19.47466 -16.15823 1.000 48.34093  ? 172 LEU   B CD1 1 
ATOM   3823 C  CD2 . LEU   B 1 175 ? 12.15027  20.06674 -16.00359 1.000 60.88536  ? 172 LEU   B CD2 1 
ATOM   3824 N  N   . PHE   B 1 176 ? 10.14001  25.05722 -15.37362 1.000 62.94777  ? 173 PHE   B N   1 
ATOM   3825 C  CA  . PHE   B 1 176 ? 9.82685   26.40348 -15.84272 1.000 66.42325  ? 173 PHE   B CA  1 
ATOM   3826 C  C   . PHE   B 1 176 ? 11.01393  27.34517 -15.69802 1.000 71.52984  ? 173 PHE   B C   1 
ATOM   3827 O  O   . PHE   B 1 176 ? 11.09918  28.34716 -16.41687 1.000 71.12034  ? 173 PHE   B O   1 
ATOM   3828 C  CB  . PHE   B 1 176 ? 8.61319   26.95159 -15.09088 1.000 71.02507  ? 173 PHE   B CB  1 
ATOM   3829 C  CG  . PHE   B 1 176 ? 7.35196   26.16461 -15.31879 1.000 73.97179  ? 173 PHE   B CG  1 
ATOM   3830 C  CD1 . PHE   B 1 176 ? 7.21794   25.34122 -16.42750 1.000 74.64245  ? 173 PHE   B CD1 1 
ATOM   3831 C  CD2 . PHE   B 1 176 ? 6.30152   26.24064 -14.41772 1.000 72.25932  ? 173 PHE   B CD2 1 
ATOM   3832 C  CE1 . PHE   B 1 176 ? 6.05639   24.61318 -16.63539 1.000 72.75638  ? 173 PHE   B CE1 1 
ATOM   3833 C  CE2 . PHE   B 1 176 ? 5.14035   25.51582 -14.62387 1.000 71.38635  ? 173 PHE   B CE2 1 
ATOM   3834 C  CZ  . PHE   B 1 176 ? 5.01734   24.70124 -15.73155 1.000 72.64540  ? 173 PHE   B CZ  1 
ATOM   3835 N  N   . GLN   B 1 177 ? 11.93081  27.05258 -14.77505 1.000 73.20143  ? 174 GLN   B N   1 
ATOM   3836 C  CA  A GLN   B 1 177 ? 13.13115  27.86805 -14.64033 0.488 74.09573  ? 174 GLN   B CA  1 
ATOM   3837 C  CA  B GLN   B 1 177 ? 13.12712  27.87284 -14.64418 0.512 73.82344  ? 174 GLN   B CA  1 
ATOM   3838 C  C   . GLN   B 1 177 ? 14.10102  27.65292 -15.79287 1.000 75.86373  ? 174 GLN   B C   1 
ATOM   3839 O  O   . GLN   B 1 177 ? 14.91783  28.53725 -16.07702 1.000 77.00382  ? 174 GLN   B O   1 
ATOM   3840 C  CB  A GLN   B 1 177 ? 13.83128  27.56899 -13.31234 0.488 75.34354  ? 174 GLN   B CB  1 
ATOM   3841 C  CB  B GLN   B 1 177 ? 13.81625  27.58902 -13.30902 0.512 75.11254  ? 174 GLN   B CB  1 
ATOM   3842 C  CG  A GLN   B 1 177 ? 13.02983  27.94288 -12.07021 0.488 75.61850  ? 174 GLN   B CG  1 
ATOM   3843 C  CG  B GLN   B 1 177 ? 12.96810  27.92669 -12.09252 0.512 75.64811  ? 174 GLN   B CG  1 
ATOM   3844 C  CD  A GLN   B 1 177 ? 13.05518  29.43201 -11.76680 0.488 74.23599  ? 174 GLN   B CD  1 
ATOM   3845 C  CD  B GLN   B 1 177 ? 13.58771  27.44117 -10.79527 0.512 76.61674  ? 174 GLN   B CD  1 
ATOM   3846 O  OE1 A GLN   B 1 177 ? 13.69215  30.21454 -12.47275 0.488 75.59326  ? 174 GLN   B OE1 1 
ATOM   3847 O  OE1 B GLN   B 1 177 ? 14.77710  27.12458 -10.74041 0.512 78.70672  ? 174 GLN   B OE1 1 
ATOM   3848 N  NE2 A GLN   B 1 177 ? 12.36061  29.82874 -10.70674 0.488 74.80470  ? 174 GLN   B NE2 1 
ATOM   3849 N  NE2 B GLN   B 1 177 ? 12.77995  27.37389 -9.74372  0.512 74.41143  ? 174 GLN   B NE2 1 
ATOM   3850 N  N   . HIS   B 1 178 ? 14.02862  26.50242 -16.45864 1.000 74.44792  ? 175 HIS   B N   1 
ATOM   3851 C  CA  . HIS   B 1 178 ? 14.85773  26.20194 -17.61460 1.000 69.65211  ? 175 HIS   B CA  1 
ATOM   3852 C  C   . HIS   B 1 178 ? 14.11893  26.42635 -18.92859 1.000 66.74458  ? 175 HIS   B C   1 
ATOM   3853 O  O   . HIS   B 1 178 ? 14.57494  25.95663 -19.97629 1.000 65.46241  ? 175 HIS   B O   1 
ATOM   3854 C  CB  . HIS   B 1 178 ? 15.36835  24.76213 -17.53260 1.000 69.70471  ? 175 HIS   B CB  1 
ATOM   3855 C  CG  . HIS   B 1 178 ? 16.25802  24.50295 -16.35577 1.000 79.35777  ? 175 HIS   B CG  1 
ATOM   3856 N  ND1 . HIS   B 1 178 ? 17.63240  24.48740 -16.45509 1.000 82.22977  ? 175 HIS   B ND1 1 
ATOM   3857 C  CD2 . HIS   B 1 178 ? 15.97276  24.25237 -15.05545 1.000 71.31410  ? 175 HIS   B CD2 1 
ATOM   3858 C  CE1 . HIS   B 1 178 ? 18.15635  24.23701 -15.26892 1.000 101.20431 ? 175 HIS   B CE1 1 
ATOM   3859 N  NE2 . HIS   B 1 178 ? 17.17106  24.09072 -14.40125 1.000 93.58715  ? 175 HIS   B NE2 1 
ATOM   3860 N  N   . ALA   B 1 179 ? 12.98927  27.13021 -18.89294 1.000 67.64618  ? 176 ALA   B N   1 
ATOM   3861 C  CA  . ALA   B 1 179 ? 12.19474  27.42444 -20.07533 1.000 64.20512  ? 176 ALA   B CA  1 
ATOM   3862 C  C   . ALA   B 1 179 ? 12.15108  28.92738 -20.31431 1.000 63.05340  ? 176 ALA   B C   1 
ATOM   3863 O  O   . ALA   B 1 179 ? 12.38050  29.72979 -19.40551 1.000 65.14255  ? 176 ALA   B O   1 
ATOM   3864 C  CB  . ALA   B 1 179 ? 10.76739  26.87856 -19.94344 1.000 64.07366  ? 176 ALA   B CB  1 
ATOM   3865 N  N   . ASN   B 1 180 ? 11.84480  29.29999 -21.55634 1.000 70.03929  ? 177 ASN   B N   1 
ATOM   3866 C  CA  . ASN   B 1 180 ? 11.77585  30.70376 -21.96679 1.000 70.61544  ? 177 ASN   B CA  1 
ATOM   3867 C  C   . ASN   B 1 180 ? 10.41019  31.26679 -21.59571 1.000 71.70055  ? 177 ASN   B C   1 
ATOM   3868 O  O   . ASN   B 1 180 ? 9.47033   31.24723 -22.38818 1.000 79.17691  ? 177 ASN   B O   1 
ATOM   3869 C  CB  . ASN   B 1 180 ? 12.03551  30.84374 -23.45983 1.000 67.36557  ? 177 ASN   B CB  1 
ATOM   3870 C  CG  . ASN   B 1 180 ? 12.20678  32.28980 -23.88786 1.000 74.29715  ? 177 ASN   B CG  1 
ATOM   3871 O  OD1 . ASN   B 1 180 ? 11.88100  33.21577 -23.14491 1.000 72.67254  ? 177 ASN   B OD1 1 
ATOM   3872 N  ND2 . ASN   B 1 180 ? 12.72484  32.48959 -25.09525 1.000 76.65842  ? 177 ASN   B ND2 1 
ATOM   3873 N  N   . LEU   B 1 181 ? 10.30181  31.78354 -20.37295 1.000 75.26795  ? 178 LEU   B N   1 
ATOM   3874 C  CA  . LEU   B 1 181 ? 9.08931   32.43622 -19.89387 1.000 74.43410  ? 178 LEU   B CA  1 
ATOM   3875 C  C   . LEU   B 1 181 ? 9.30588   33.92456 -19.62971 1.000 82.03727  ? 178 LEU   B C   1 
ATOM   3876 O  O   . LEU   B 1 181 ? 8.69899   34.49151 -18.71805 1.000 88.41743  ? 178 LEU   B O   1 
ATOM   3877 C  CB  . LEU   B 1 181 ? 8.56791   31.74289 -18.63696 1.000 71.71001  ? 178 LEU   B CB  1 
ATOM   3878 C  CG  . LEU   B 1 181 ? 8.22018   30.26237 -18.79767 1.000 74.50536  ? 178 LEU   B CG  1 
ATOM   3879 C  CD1 . LEU   B 1 181 ? 7.69036   29.68127 -17.49560 1.000 71.59744  ? 178 LEU   B CD1 1 
ATOM   3880 C  CD2 . LEU   B 1 181 ? 7.21130   30.07773 -19.91849 1.000 71.93187  ? 178 LEU   B CD2 1 
ATOM   3881 N  N   . ASP   B 1 182 ? 10.17823  34.56748 -20.41256 1.000 86.65724  ? 179 ASP   B N   1 
ATOM   3882 C  CA  . ASP   B 1 182 ? 10.47990  35.97721 -20.17980 1.000 94.14615  ? 179 ASP   B CA  1 
ATOM   3883 C  C   . ASP   B 1 182 ? 9.30518   36.88237 -20.53251 1.000 94.99570  ? 179 ASP   B C   1 
ATOM   3884 O  O   . ASP   B 1 182 ? 9.12177   37.92892 -19.89995 1.000 103.40243 ? 179 ASP   B O   1 
ATOM   3885 C  CB  . ASP   B 1 182 ? 11.71204  36.39758 -20.98629 1.000 97.06739  ? 179 ASP   B CB  1 
ATOM   3886 C  CG  . ASP   B 1 182 ? 12.98182  35.69762 -20.53452 1.000 96.27899  ? 179 ASP   B CG  1 
ATOM   3887 O  OD1 . ASP   B 1 182 ? 13.05723  35.28404 -19.35640 1.000 94.53187  ? 179 ASP   B OD1 1 
ATOM   3888 O  OD2 . ASP   B 1 182 ? 13.91171  35.57419 -21.36101 1.000 92.91292  ? 179 ASP   B OD2 1 
ATOM   3889 N  N   . SER   B 1 183 ? 8.49923   36.50078 -21.52469 1.000 93.22688  ? 180 SER   B N   1 
ATOM   3890 C  CA  . SER   B 1 183 ? 7.36795   37.32103 -21.94290 1.000 93.14166  ? 180 SER   B CA  1 
ATOM   3891 C  C   . SER   B 1 183 ? 6.19973   37.28796 -20.96518 1.000 96.11387  ? 180 SER   B C   1 
ATOM   3892 O  O   . SER   B 1 183 ? 5.29869   38.12519 -21.08155 1.000 100.82209 ? 180 SER   B O   1 
ATOM   3893 C  CB  . SER   B 1 183 ? 6.89098   36.88080 -23.32599 1.000 92.01345  ? 180 SER   B CB  1 
ATOM   3894 O  OG  . SER   B 1 183 ? 7.95240   36.93417 -24.26084 1.000 103.49335 ? 180 SER   B OG  1 
ATOM   3895 N  N   . CYS   B 1 184 ? 6.18952   36.36352 -20.00997 1.000 87.33239  ? 181 CYS   B N   1 
ATOM   3896 C  CA  . CYS   B 1 184 ? 5.03566   36.19325 -19.13725 1.000 94.25391  ? 181 CYS   B CA  1 
ATOM   3897 C  C   . CYS   B 1 184 ? 4.97974   37.29094 -18.08159 1.000 105.39699 ? 181 CYS   B C   1 
ATOM   3898 O  O   . CYS   B 1 184 ? 5.94499   37.50443 -17.34163 1.000 103.88582 ? 181 CYS   B O   1 
ATOM   3899 C  CB  . CYS   B 1 184 ? 5.07728   34.82203 -18.46605 1.000 89.58859  ? 181 CYS   B CB  1 
ATOM   3900 S  SG  . CYS   B 1 184 ? 5.04440   33.44560 -19.62695 1.000 91.89367  ? 181 CYS   B SG  1 
ATOM   3901 N  N   . LYS   B 1 185 ? 3.83848   37.97950 -18.01047 1.000 105.73630 ? 182 LYS   B N   1 
ATOM   3902 C  CA  . LYS   B 1 185 ? 3.60285   39.03205 -17.03177 1.000 98.31078  ? 182 LYS   B CA  1 
ATOM   3903 C  C   . LYS   B 1 185 ? 2.30826   38.75019 -16.28382 1.000 99.82294  ? 182 LYS   B C   1 
ATOM   3904 O  O   . LYS   B 1 185 ? 1.34517   38.23911 -16.86277 1.000 100.07977 ? 182 LYS   B O   1 
ATOM   3905 C  CB  . LYS   B 1 185 ? 3.52837   40.41747 -17.69315 1.000 95.89547  ? 182 LYS   B CB  1 
ATOM   3906 C  CG  . LYS   B 1 185 ? 4.70703   40.75256 -18.59425 1.000 105.14796 ? 182 LYS   B CG  1 
ATOM   3907 C  CD  . LYS   B 1 185 ? 4.72121   42.22977 -18.96386 1.000 103.72318 ? 182 LYS   B CD  1 
ATOM   3908 C  CE  . LYS   B 1 185 ? 3.41476   42.66268 -19.61585 1.000 110.44280 ? 182 LYS   B CE  1 
ATOM   3909 N  NZ  . LYS   B 1 185 ? 3.17339   41.97858 -20.91684 1.000 108.83061 ? 182 LYS   B NZ  1 
ATOM   3910 N  N   . ARG   B 1 186 ? 2.29388   39.08362 -14.99348 1.000 104.89434 ? 183 ARG   B N   1 
ATOM   3911 C  CA  . ARG   B 1 186 ? 1.10756   38.94564 -14.15353 1.000 101.45853 ? 183 ARG   B CA  1 
ATOM   3912 C  C   . ARG   B 1 186 ? 1.08669   40.09312 -13.15682 1.000 117.43227 ? 183 ARG   B C   1 
ATOM   3913 O  O   . ARG   B 1 186 ? 2.03102   40.24739 -12.37596 1.000 123.27482 ? 183 ARG   B O   1 
ATOM   3914 C  CB  . ARG   B 1 186 ? 1.09934   37.61040 -13.40351 1.000 90.29269  ? 183 ARG   B CB  1 
ATOM   3915 C  CG  . ARG   B 1 186 ? 0.01953   37.52965 -12.33297 1.000 87.06359  ? 183 ARG   B CG  1 
ATOM   3916 C  CD  . ARG   B 1 186 ? 0.21029   36.33735 -11.40734 1.000 90.87818  ? 183 ARG   B CD  1 
ATOM   3917 N  NE  . ARG   B 1 186 ? -0.07957  35.05617 -12.03838 1.000 91.51428  ? 183 ARG   B NE  1 
ATOM   3918 C  CZ  . ARG   B 1 186 ? -0.02200  33.88949 -11.40979 1.000 96.50463  ? 183 ARG   B CZ  1 
ATOM   3919 N  NH1 . ARG   B 1 186 ? 0.30469   33.80938 -10.13022 1.000 99.24259  ? 183 ARG   B NH1 1 
ATOM   3920 N  NH2 . ARG   B 1 186 ? -0.29500  32.77490 -12.08188 1.000 98.59948  ? 183 ARG   B NH2 1 
ATOM   3921 N  N   . VAL   B 1 187 ? 0.02180   40.88968 -13.17001 1.000 122.06313 ? 184 VAL   B N   1 
ATOM   3922 C  CA  . VAL   B 1 187 ? -0.15023  41.96833 -12.20289 1.000 123.68394 ? 184 VAL   B CA  1 
ATOM   3923 C  C   . VAL   B 1 187 ? -1.15898  41.50290 -11.16175 1.000 122.38473 ? 184 VAL   B C   1 
ATOM   3924 O  O   . VAL   B 1 187 ? -2.31175  41.20207 -11.49333 1.000 130.10247 ? 184 VAL   B O   1 
ATOM   3925 C  CB  . VAL   B 1 187 ? -0.61139  43.26772 -12.88148 1.000 118.10334 ? 184 VAL   B CB  1 
ATOM   3926 C  CG1 . VAL   B 1 187 ? -0.69257  44.39676 -11.85914 1.000 114.89719 ? 184 VAL   B CG1 1 
ATOM   3927 C  CG2 . VAL   B 1 187 ? 0.32394   43.63230 -14.03078 1.000 109.13067 ? 184 VAL   B CG2 1 
ATOM   3928 N  N   . LEU   B 1 188 ? -0.73478  41.45736 -9.90336  1.000 111.13633 ? 185 LEU   B N   1 
ATOM   3929 C  CA  . LEU   B 1 188 ? -1.59699  40.98157 -8.82682  1.000 120.55545 ? 185 LEU   B CA  1 
ATOM   3930 C  C   . LEU   B 1 188 ? -1.81003  42.05772 -7.76368  1.000 127.34097 ? 185 LEU   B C   1 
ATOM   3931 O  O   . LEU   B 1 188 ? -2.38003  41.79671 -6.70160  1.000 121.68230 ? 185 LEU   B O   1 
ATOM   3932 C  CB  . LEU   B 1 188 ? -1.00971  39.71702 -8.19388  1.000 111.27255 ? 185 LEU   B CB  1 
ATOM   3933 N  N   . THR   B 1 201 ? 3.86764   43.99908 -10.66024 1.000 108.29235 ? 198 THR   B N   1 
ATOM   3934 C  CA  . THR   B 1 201 ? 4.05425   43.19172 -11.86132 1.000 113.69991 ? 198 THR   B CA  1 
ATOM   3935 C  C   . THR   B 1 201 ? 5.04229   42.05090 -11.60914 1.000 115.38719 ? 198 THR   B C   1 
ATOM   3936 O  O   . THR   B 1 201 ? 6.08899   42.24452 -10.98750 1.000 119.28378 ? 198 THR   B O   1 
ATOM   3937 C  CB  . THR   B 1 201 ? 4.54809   44.05418 -13.05031 1.000 113.91927 ? 198 THR   B CB  1 
ATOM   3938 O  OG1 . THR   B 1 201 ? 3.60028   45.09808 -13.31417 1.000 113.87358 ? 198 THR   B OG1 1 
ATOM   3939 C  CG2 . THR   B 1 201 ? 4.71800   43.20599 -14.30731 1.000 109.94132 ? 198 THR   B CG2 1 
ATOM   3940 N  N   . LEU   B 1 202 ? 4.70199   40.86115 -12.10006 1.000 114.95503 ? 199 LEU   B N   1 
ATOM   3941 C  CA  . LEU   B 1 202 ? 5.53235   39.67475 -11.96341 1.000 111.07393 ? 199 LEU   B CA  1 
ATOM   3942 C  C   . LEU   B 1 202 ? 5.96855   39.19158 -13.34038 1.000 108.58456 ? 199 LEU   B C   1 
ATOM   3943 O  O   . LEU   B 1 202 ? 5.21543   39.29594 -14.31226 1.000 105.73719 ? 199 LEU   B O   1 
ATOM   3944 C  CB  . LEU   B 1 202 ? 4.77542   38.55169 -11.24594 1.000 103.27179 ? 199 LEU   B CB  1 
ATOM   3945 C  CG  . LEU   B 1 202 ? 4.29749   38.79578 -9.81464  1.000 101.65679 ? 199 LEU   B CG  1 
ATOM   3946 C  CD1 . LEU   B 1 202 ? 3.76907   37.49576 -9.21650  1.000 95.72358  ? 199 LEU   B CD1 1 
ATOM   3947 C  CD2 . LEU   B 1 202 ? 5.40638   39.39374 -8.95181  1.000 113.64486 ? 199 LEU   B CD2 1 
ATOM   3948 N  N   . LYS   B 1 203 ? 7.19180   38.67524 -13.42615 1.000 104.57728 ? 200 LYS   B N   1 
ATOM   3949 C  CA  . LYS   B 1 203 ? 7.70924   38.10459 -14.66107 1.000 100.66815 ? 200 LYS   B CA  1 
ATOM   3950 C  C   . LYS   B 1 203 ? 8.22741   36.69696 -14.40316 1.000 99.42081  ? 200 LYS   B C   1 
ATOM   3951 O  O   . LYS   B 1 203 ? 8.44981   36.28985 -13.26032 1.000 93.12989  ? 200 LYS   B O   1 
ATOM   3952 C  CB  . LYS   B 1 203 ? 8.81575   38.96816 -15.29140 1.000 104.36408 ? 200 LYS   B CB  1 
ATOM   3953 C  CG  . LYS   B 1 203 ? 8.31860   39.97421 -16.32861 1.000 106.28862 ? 200 LYS   B CG  1 
ATOM   3954 C  CD  . LYS   B 1 203 ? 7.76205   41.23785 -15.69744 1.000 109.85359 ? 200 LYS   B CD  1 
ATOM   3955 C  CE  . LYS   B 1 203 ? 8.86560   42.25398 -15.44220 1.000 119.07648 ? 200 LYS   B CE  1 
ATOM   3956 N  NZ  . LYS   B 1 203 ? 8.33042   43.56593 -14.97899 1.000 110.89445 ? 200 LYS   B NZ  1 
ATOM   3957 N  N   . GLY   B 1 204 ? 8.40729   35.95537 -15.49637 1.000 96.96239  ? 201 GLY   B N   1 
ATOM   3958 C  CA  . GLY   B 1 204 ? 9.00000   34.63369 -15.44046 1.000 81.03528  ? 201 GLY   B CA  1 
ATOM   3959 C  C   . GLY   B 1 204 ? 8.10592   33.59353 -14.78520 1.000 83.11047  ? 201 GLY   B C   1 
ATOM   3960 O  O   . GLY   B 1 204 ? 6.87737   33.61599 -14.90289 1.000 90.42888  ? 201 GLY   B O   1 
ATOM   3961 N  N   . VAL   B 1 205 ? 8.75067   32.66598 -14.07139 1.000 79.40277  ? 202 VAL   B N   1 
ATOM   3962 C  CA  . VAL   B 1 205 ? 8.05563   31.51771 -13.49354 1.000 79.31767  ? 202 VAL   B CA  1 
ATOM   3963 C  C   . VAL   B 1 205 ? 6.96024   31.95435 -12.53030 1.000 92.21147  ? 202 VAL   B C   1 
ATOM   3964 O  O   . VAL   B 1 205 ? 5.92156   31.29059 -12.41619 1.000 91.59745  ? 202 VAL   B O   1 
ATOM   3965 C  CB  . VAL   B 1 205 ? 9.07543   30.58834 -12.80389 1.000 80.55970  ? 202 VAL   B CB  1 
ATOM   3966 C  CG1 . VAL   B 1 205 ? 8.39418   29.33373 -12.25981 1.000 75.50178  ? 202 VAL   B CG1 1 
ATOM   3967 C  CG2 . VAL   B 1 205 ? 10.20032  30.23145 -13.76641 1.000 83.97877  ? 202 VAL   B CG2 1 
ATOM   3968 N  N   . GLU   B 1 206 ? 7.16335   33.07028 -11.82677 1.000 102.39489 ? 203 GLU   B N   1 
ATOM   3969 C  CA  . GLU   B 1 206 ? 6.17090   33.53299 -10.86338 1.000 99.73762  ? 203 GLU   B CA  1 
ATOM   3970 C  C   . GLU   B 1 206 ? 4.90203   34.04472 -11.53217 1.000 94.71015  ? 203 GLU   B C   1 
ATOM   3971 O  O   . GLU   B 1 206 ? 3.86514   34.14378 -10.86722 1.000 98.62949  ? 203 GLU   B O   1 
ATOM   3972 C  CB  . GLU   B 1 206 ? 6.77030   34.63206 -9.98564  1.000 104.53019 ? 203 GLU   B CB  1 
ATOM   3973 C  CG  . GLU   B 1 206 ? 8.02597   34.21630 -9.23838  1.000 106.78560 ? 203 GLU   B CG  1 
ATOM   3974 C  CD  . GLU   B 1 206 ? 8.72088   35.39050 -8.57694  1.000 125.10102 ? 203 GLU   B CD  1 
ATOM   3975 O  OE1 . GLU   B 1 206 ? 8.04533   36.15838 -7.85839  1.000 122.19258 ? 203 GLU   B OE1 1 
ATOM   3976 O  OE2 . GLU   B 1 206 ? 9.94147   35.55300 -8.78747  1.000 128.54999 ? 203 GLU   B OE2 1 
ATOM   3977 N  N   . ALA   B 1 207 ? 4.95594   34.35831 -12.82907 1.000 93.69934  ? 204 ALA   B N   1 
ATOM   3978 C  CA  . ALA   B 1 207 ? 3.78492   34.85591 -13.54189 1.000 98.37723  ? 204 ALA   B CA  1 
ATOM   3979 C  C   . ALA   B 1 207 ? 2.82450   33.74659 -13.95209 1.000 93.94473  ? 204 ALA   B C   1 
ATOM   3980 O  O   . ALA   B 1 207 ? 1.65203   34.03047 -14.21790 1.000 93.11161  ? 204 ALA   B O   1 
ATOM   3981 C  CB  . ALA   B 1 207 ? 4.21687   35.64348 -14.78276 1.000 93.01779  ? 204 ALA   B CB  1 
ATOM   3982 N  N   . VAL   B 1 208 ? 3.28714   32.49914 -14.00520 1.000 90.87786  ? 205 VAL   B N   1 
ATOM   3983 C  CA  . VAL   B 1 208 ? 2.46447   31.38443 -14.46327 1.000 81.14433  ? 205 VAL   B CA  1 
ATOM   3984 C  C   . VAL   B 1 208 ? 2.09467   30.42838 -13.34243 1.000 85.43905  ? 205 VAL   B C   1 
ATOM   3985 O  O   . VAL   B 1 208 ? 1.30571   29.49804 -13.57913 1.000 85.56594  ? 205 VAL   B O   1 
ATOM   3986 C  CB  . VAL   B 1 208 ? 3.14987   30.60977 -15.60897 1.000 72.17617  ? 205 VAL   B CB  1 
ATOM   3987 C  CG1 . VAL   B 1 208 ? 3.61782   31.57555 -16.68222 1.000 71.38622  ? 205 VAL   B CG1 1 
ATOM   3988 C  CG2 . VAL   B 1 208 ? 4.30741   29.77753 -15.08002 1.000 71.98170  ? 205 VAL   B CG2 1 
ATOM   3989 N  N   . MET   B 1 209 ? 2.63142   30.61460 -12.13970 1.000 83.87161  ? 206 MET   B N   1 
ATOM   3990 C  CA  . MET   B 1 209 ? 2.38080   29.72795 -11.01748 1.000 85.49567  ? 206 MET   B CA  1 
ATOM   3991 C  C   . MET   B 1 209 ? 1.70547   30.49537 -9.89155  1.000 94.65447  ? 206 MET   B C   1 
ATOM   3992 O  O   . MET   B 1 209 ? 2.04272   31.65384 -9.62103  1.000 93.96176  ? 206 MET   B O   1 
ATOM   3993 C  CB  . MET   B 1 209 ? 3.68441   29.10783 -10.50231 1.000 78.93656  ? 206 MET   B CB  1 
ATOM   3994 C  CG  . MET   B 1 209 ? 4.36971   28.17513 -11.47640 1.000 82.14368  ? 206 MET   B CG  1 
ATOM   3995 S  SD  . MET   B 1 209 ? 5.65791   27.20948 -10.66711 1.000 88.60815  ? 206 MET   B SD  1 
ATOM   3996 C  CE  . MET   B 1 209 ? 4.73653   26.44621 -9.33320  1.000 95.45632  ? 206 MET   B CE  1 
ATOM   3997 N  N   . TYR   B 1 210 ? 0.74942   29.84070 -9.23811  1.000 93.97523  ? 207 TYR   B N   1 
ATOM   3998 C  CA  . TYR   B 1 210 ? 0.07800   30.39704 -8.07364  1.000 97.36272  ? 207 TYR   B CA  1 
ATOM   3999 C  C   . TYR   B 1 210 ? -0.30537  29.27900 -7.12136  1.000 96.95195  ? 207 TYR   B C   1 
ATOM   4000 O  O   . TYR   B 1 210 ? -0.85471  28.25562 -7.54125  1.000 85.40985  ? 207 TYR   B O   1 
ATOM   4001 C  CB  . TYR   B 1 210 ? -1.16600  31.19698 -8.46121  1.000 101.39721 ? 207 TYR   B CB  1 
ATOM   4002 C  CG  . TYR   B 1 210 ? -2.00109  31.57874 -7.26141  1.000 114.98264 ? 207 TYR   B CG  1 
ATOM   4003 C  CD1 . TYR   B 1 210 ? -1.62812  32.61955 -6.42219  1.000 118.67336 ? 207 TYR   B CD1 1 
ATOM   4004 C  CD2 . TYR   B 1 210 ? -3.16192  30.87831 -6.95918  1.000 115.13705 ? 207 TYR   B CD2 1 
ATOM   4005 C  CE1 . TYR   B 1 210 ? -2.39532  32.95434 -5.31760  1.000 123.77877 ? 207 TYR   B CE1 1 
ATOM   4006 C  CE2 . TYR   B 1 210 ? -3.93254  31.20457 -5.86606  1.000 117.32439 ? 207 TYR   B CE2 1 
ATOM   4007 C  CZ  . TYR   B 1 210 ? -3.54861  32.24086 -5.04754  1.000 124.00790 ? 207 TYR   B CZ  1 
ATOM   4008 O  OH  . TYR   B 1 210 ? -4.32722  32.55858 -3.95674  1.000 122.17458 ? 207 TYR   B OH  1 
ATOM   4009 N  N   . MET   B 1 211 ? -0.02753  29.49193 -5.83999  1.000 103.68689 ? 208 MET   B N   1 
ATOM   4010 C  CA  . MET   B 1 211 ? -0.39252  28.55956 -4.78443  1.000 103.19089 ? 208 MET   B CA  1 
ATOM   4011 C  C   . MET   B 1 211 ? -1.49016  29.18491 -3.93595  1.000 110.42213 ? 208 MET   B C   1 
ATOM   4012 O  O   . MET   B 1 211 ? -1.33202  30.30712 -3.44276  1.000 112.51371 ? 208 MET   B O   1 
ATOM   4013 C  CB  . MET   B 1 211 ? 0.81579   28.21340 -3.91922  1.000 83.64499  ? 208 MET   B CB  1 
ATOM   4014 C  CG  . MET   B 1 211 ? 0.52642   27.14348 -2.90252  1.000 94.07754  ? 208 MET   B CG  1 
ATOM   4015 S  SD  . MET   B 1 211 ? 0.06991   25.62544 -3.75204  1.000 110.24356 ? 208 MET   B SD  1 
ATOM   4016 C  CE  . MET   B 1 211 ? -0.28663  24.54462 -2.37475  1.000 88.35288  ? 208 MET   B CE  1 
ATOM   4017 N  N   . GLY   B 1 212 ? -2.59887  28.46868 -3.77745  1.000 103.89527 ? 209 GLY   B N   1 
ATOM   4018 C  CA  . GLY   B 1 212 ? -3.70811  28.98480 -3.00244  1.000 96.54628  ? 209 GLY   B CA  1 
ATOM   4019 C  C   . GLY   B 1 212 ? -5.04325  28.36038 -3.34678  1.000 102.43463 ? 209 GLY   B C   1 
ATOM   4020 O  O   . GLY   B 1 212 ? -5.62697  27.63858 -2.53310  1.000 102.42357 ? 209 GLY   B O   1 
ATOM   4021 N  N   . THR   B 1 213 ? -5.53781  28.63330 -4.55171  1.000 103.73598 ? 210 THR   B N   1 
ATOM   4022 C  CA  . THR   B 1 213 ? -6.80307  28.09563 -5.02357  1.000 96.68561  ? 210 THR   B CA  1 
ATOM   4023 C  C   . THR   B 1 213 ? -6.59005  27.32249 -6.31850  1.000 98.54388  ? 210 THR   B C   1 
ATOM   4024 O  O   . THR   B 1 213 ? -5.64640  27.58318 -7.07272  1.000 97.80603  ? 210 THR   B O   1 
ATOM   4025 C  CB  . THR   B 1 213 ? -7.83646  29.21732 -5.24576  1.000 95.09547  ? 210 THR   B CB  1 
ATOM   4026 O  OG1 . THR   B 1 213 ? -9.06921  28.66172 -5.72293  1.000 95.40907  ? 210 THR   B OG1 1 
ATOM   4027 C  CG2 . THR   B 1 213 ? -7.32246  30.23488 -6.24774  1.000 96.00356  ? 210 THR   B CG2 1 
ATOM   4028 N  N   . LEU   B 1 214 ? -7.47938  26.36046 -6.56724  1.000 93.06625  ? 211 LEU   B N   1 
ATOM   4029 C  CA  . LEU   B 1 214 ? -7.48250  25.62850 -7.82499  1.000 83.91682  ? 211 LEU   B CA  1 
ATOM   4030 C  C   . LEU   B 1 214 ? -8.29205  26.32554 -8.90950  1.000 89.50388  ? 211 LEU   B C   1 
ATOM   4031 O  O   . LEU   B 1 214 ? -8.05880  26.07445 -10.09741 1.000 90.31138  ? 211 LEU   B O   1 
ATOM   4032 C  CB  . LEU   B 1 214 ? -8.04819  24.22029 -7.62243  1.000 73.90565  ? 211 LEU   B CB  1 
ATOM   4033 C  CG  . LEU   B 1 214 ? -7.34695  23.29586 -6.63211  1.000 76.89284  ? 211 LEU   B CG  1 
ATOM   4034 C  CD1 . LEU   B 1 214 ? -8.15674  22.02609 -6.46930  1.000 77.86177  ? 211 LEU   B CD1 1 
ATOM   4035 C  CD2 . LEU   B 1 214 ? -5.94778  22.98063 -7.09989  1.000 76.44975  ? 211 LEU   B CD2 1 
ATOM   4036 N  N   . SER   B 1 215 ? -9.22211  27.19789 -8.52967  1.000 84.72974  ? 212 SER   B N   1 
ATOM   4037 C  CA  . SER   B 1 215 ? -10.14364 27.83067 -9.46395  1.000 89.22799  ? 212 SER   B CA  1 
ATOM   4038 C  C   . SER   B 1 215 ? -9.51180  29.09557 -10.03105 1.000 92.52934  ? 212 SER   B C   1 
ATOM   4039 O  O   . SER   B 1 215 ? -9.09051  29.97800 -9.27575  1.000 96.26530  ? 212 SER   B O   1 
ATOM   4040 C  CB  . SER   B 1 215 ? -11.46951 28.15315 -8.77443  1.000 83.31758  ? 212 SER   B CB  1 
ATOM   4041 O  OG  . SER   B 1 215 ? -12.26624 29.02091 -9.56452  1.000 97.22671  ? 212 SER   B OG  1 
ATOM   4042 N  N   . TYR   B 1 216 ? -9.43100  29.17533 -11.36047 1.000 95.16599  ? 213 TYR   B N   1 
ATOM   4043 C  CA  . TYR   B 1 216 ? -8.99758  30.41779 -11.98662 1.000 94.72205  ? 213 TYR   B CA  1 
ATOM   4044 C  C   . TYR   B 1 216 ? -9.99309  31.53857 -11.71364 1.000 98.74675  ? 213 TYR   B C   1 
ATOM   4045 O  O   . TYR   B 1 216 ? -9.60647  32.71100 -11.64480 1.000 102.32033 ? 213 TYR   B O   1 
ATOM   4046 C  CB  . TYR   B 1 216 ? -8.81936  30.22001 -13.49228 1.000 88.99004  ? 213 TYR   B CB  1 
ATOM   4047 C  CG  . TYR   B 1 216 ? -7.91460  31.24458 -14.13991 1.000 90.32817  ? 213 TYR   B CG  1 
ATOM   4048 C  CD1 . TYR   B 1 216 ? -6.88717  31.84443 -13.42106 1.000 96.13881  ? 213 TYR   B CD1 1 
ATOM   4049 C  CD2 . TYR   B 1 216 ? -8.09722  31.62580 -15.46164 1.000 88.27497  ? 213 TYR   B CD2 1 
ATOM   4050 C  CE1 . TYR   B 1 216 ? -6.05472  32.78123 -14.00748 1.000 98.69790  ? 213 TYR   B CE1 1 
ATOM   4051 C  CE2 . TYR   B 1 216 ? -7.27361  32.56613 -16.05568 1.000 88.57563  ? 213 TYR   B CE2 1 
ATOM   4052 C  CZ  . TYR   B 1 216 ? -6.25444  33.14018 -15.32521 1.000 93.57562  ? 213 TYR   B CZ  1 
ATOM   4053 O  OH  . TYR   B 1 216 ? -5.43278  34.07534 -15.91448 1.000 94.11512  ? 213 TYR   B OH  1 
ATOM   4054 N  N   . GLU   B 1 217 ? -11.27672 31.19654 -11.56411 1.000 98.79146  ? 214 GLU   B N   1 
ATOM   4055 C  CA  . GLU   B 1 217 ? -12.29744 32.20054 -11.27465 1.000 104.75339 ? 214 GLU   B CA  1 
ATOM   4056 C  C   . GLU   B 1 217 ? -12.05106 32.88136 -9.93418  1.000 102.40135 ? 214 GLU   B C   1 
ATOM   4057 O  O   . GLU   B 1 217 ? -12.11244 34.11250 -9.83282  1.000 104.08327 ? 214 GLU   B O   1 
ATOM   4058 C  CB  . GLU   B 1 217 ? -13.68435 31.55757 -11.30711 1.000 110.55352 ? 214 GLU   B CB  1 
ATOM   4059 C  CG  . GLU   B 1 217 ? -14.28158 31.45049 -12.69375 1.000 111.17865 ? 214 GLU   B CG  1 
ATOM   4060 C  CD  . GLU   B 1 217 ? -14.49602 32.81709 -13.31521 1.000 117.53854 ? 214 GLU   B CD  1 
ATOM   4061 O  OE1 . GLU   B 1 217 ? -15.43196 33.52185 -12.87727 1.000 116.79490 ? 214 GLU   B OE1 1 
ATOM   4062 O  OE2 . GLU   B 1 217 ? -13.73038 33.19302 -14.22621 1.000 120.17130 ? 214 GLU   B OE2 1 
ATOM   4063 N  N   . GLN   B 1 218 ? -11.78020 32.09730 -8.88794  1.000 97.85067  ? 215 GLN   B N   1 
ATOM   4064 C  CA  . GLN   B 1 218 ? -11.47577 32.69638 -7.59197  1.000 103.50941 ? 215 GLN   B CA  1 
ATOM   4065 C  C   . GLN   B 1 218 ? -10.22891 33.56711 -7.68214  1.000 107.02158 ? 215 GLN   B C   1 
ATOM   4066 O  O   . GLN   B 1 218 ? -10.16023 34.63954 -7.07130  1.000 110.20314 ? 215 GLN   B O   1 
ATOM   4067 C  CB  . GLN   B 1 218 ? -11.30117 31.60476 -6.53564  1.000 85.48671  ? 215 GLN   B CB  1 
ATOM   4068 N  N   . PHE   B 1 219 ? -9.23901  33.12346 -8.45845  1.000 103.87702 ? 216 PHE   B N   1 
ATOM   4069 C  CA  . PHE   B 1 219 ? -8.04658  33.92578 -8.70028  1.000 100.24533 ? 216 PHE   B CA  1 
ATOM   4070 C  C   . PHE   B 1 219 ? -8.36640  35.21834 -9.44071  1.000 105.24729 ? 216 PHE   B C   1 
ATOM   4071 O  O   . PHE   B 1 219 ? -7.66352  36.22057 -9.26575  1.000 104.98593 ? 216 PHE   B O   1 
ATOM   4072 C  CB  . PHE   B 1 219 ? -7.02530  33.10894 -9.48851  1.000 108.11529 ? 216 PHE   B CB  1 
ATOM   4073 C  CG  . PHE   B 1 219 ? -5.70008  33.79223 -9.65341  1.000 115.78341 ? 216 PHE   B CG  1 
ATOM   4074 C  CD1 . PHE   B 1 219 ? -4.87343  34.01030 -8.56237  1.000 117.61975 ? 216 PHE   B CD1 1 
ATOM   4075 C  CD2 . PHE   B 1 219 ? -5.28111  34.21795 -10.90523 1.000 105.26940 ? 216 PHE   B CD2 1 
ATOM   4076 C  CE1 . PHE   B 1 219 ? -3.65192  34.64208 -8.71686  1.000 121.52833 ? 216 PHE   B CE1 1 
ATOM   4077 C  CE2 . PHE   B 1 219 ? -4.06391  34.84969 -11.06822 1.000 107.18212 ? 216 PHE   B CE2 1 
ATOM   4078 C  CZ  . PHE   B 1 219 ? -3.24655  35.06254 -9.97310  1.000 121.24841 ? 216 PHE   B CZ  1 
ATOM   4079 N  N   . LYS   B 1 220 ? -9.41277  35.21827 -10.27168 1.000 108.17897 ? 217 LYS   B N   1 
ATOM   4080 C  CA  . LYS   B 1 220 ? -9.74568  36.41831 -11.03511 1.000 112.22678 ? 217 LYS   B CA  1 
ATOM   4081 C  C   . LYS   B 1 220 ? -10.13562 37.57102 -10.11870 1.000 116.62419 ? 217 LYS   B C   1 
ATOM   4082 O  O   . LYS   B 1 220 ? -9.73322  38.71791 -10.35146 1.000 114.30625 ? 217 LYS   B O   1 
ATOM   4083 C  CB  . LYS   B 1 220 ? -10.86498 36.11117 -12.03127 1.000 107.69653 ? 217 LYS   B CB  1 
ATOM   4084 N  N   . LYS   B 1 221 ? -10.90783 37.28945 -9.07366  1.000 116.14788 ? 218 LYS   B N   1 
ATOM   4085 C  CA  . LYS   B 1 221 ? -11.30636 38.31400 -8.11050  1.000 117.52292 ? 218 LYS   B CA  1 
ATOM   4086 C  C   . LYS   B 1 221 ? -11.90237 37.67391 -6.86058  1.000 109.20309 ? 218 LYS   B C   1 
ATOM   4087 O  O   . LYS   B 1 221 ? -11.17771 37.18847 -5.99222  1.000 107.51765 ? 218 LYS   B O   1 
ATOM   4088 C  CB  . LYS   B 1 221 ? -12.30872 39.29074 -8.72982  1.000 118.37717 ? 218 LYS   B CB  1 
ATOM   4089 C  CG  . LYS   B 1 221 ? -12.00773 40.75092 -8.42793  1.000 115.05025 ? 218 LYS   B CG  1 
ATOM   4090 C  CD  . LYS   B 1 221 ? -13.13891 41.65710 -8.88252  1.000 116.02073 ? 218 LYS   B CD  1 
ATOM   4091 C  CE  . LYS   B 1 221 ? -12.71441 43.11840 -8.88190  1.000 117.97843 ? 218 LYS   B CE  1 
ATOM   4092 N  NZ  . LYS   B 1 221 ? -11.75334 43.42553 -9.98018  1.000 118.72439 ? 218 LYS   B NZ  1 
ATOM   4093 N  N   . THR   B 1 234 ? -7.17897  39.34797 0.85723   1.000 112.76809 ? 231 THR   B N   1 
ATOM   4094 C  CA  . THR   B 1 234 ? -7.85199  39.10567 -0.41389  1.000 116.49298 ? 231 THR   B CA  1 
ATOM   4095 C  C   . THR   B 1 234 ? -7.02429  39.63690 -1.58425  1.000 115.03631 ? 231 THR   B C   1 
ATOM   4096 O  O   . THR   B 1 234 ? -6.58018  40.78506 -1.57387  1.000 116.16300 ? 231 THR   B O   1 
ATOM   4097 C  CB  . THR   B 1 234 ? -9.24887  39.75318 -0.44151  1.000 108.12983 ? 231 THR   B CB  1 
ATOM   4098 N  N   . LYS   B 1 235 ? -6.82089  38.78694 -2.58868  1.000 117.37524 ? 232 LYS   B N   1 
ATOM   4099 C  CA  . LYS   B 1 235 ? -6.04317  39.11288 -3.77589  1.000 116.10280 ? 232 LYS   B CA  1 
ATOM   4100 C  C   . LYS   B 1 235 ? -6.89827  38.99111 -5.03252  1.000 120.69000 ? 232 LYS   B C   1 
ATOM   4101 O  O   . LYS   B 1 235 ? -7.80071  38.15048 -5.10803  1.000 112.09766 ? 232 LYS   B O   1 
ATOM   4102 C  CB  . LYS   B 1 235 ? -4.81285  38.20303 -3.89593  1.000 100.69338 ? 232 LYS   B CB  1 
ATOM   4103 N  N   . TYR   B 1 236 ? -6.62086  39.85001 -6.01643  1.000 122.92925 ? 233 TYR   B N   1 
ATOM   4104 C  CA  . TYR   B 1 236 ? -7.32760  39.80976 -7.28950  1.000 121.76420 ? 233 TYR   B CA  1 
ATOM   4105 C  C   . TYR   B 1 236 ? -6.34377  40.05547 -8.42790  1.000 129.30392 ? 233 TYR   B C   1 
ATOM   4106 O  O   . TYR   B 1 236 ? -5.34519  40.76375 -8.26799  1.000 134.98839 ? 233 TYR   B O   1 
ATOM   4107 C  CB  . TYR   B 1 236 ? -8.46144  40.84598 -7.33767  1.000 115.58124 ? 233 TYR   B CB  1 
ATOM   4108 N  N   . LEU   B 1 237 ? -6.64710  39.46450 -9.58540  1.000 127.82886 ? 234 LEU   B N   1 
ATOM   4109 C  CA  . LEU   B 1 237 ? -5.78177  39.51528 -10.76011 1.000 126.66707 ? 234 LEU   B CA  1 
ATOM   4110 C  C   . LEU   B 1 237 ? -6.14808  40.69855 -11.64763 1.000 127.60850 ? 234 LEU   B C   1 
ATOM   4111 O  O   . LEU   B 1 237 ? -7.32857  40.92409 -11.93514 1.000 125.00182 ? 234 LEU   B O   1 
ATOM   4112 C  CB  . LEU   B 1 237 ? -5.87584  38.21294 -11.55742 1.000 116.31457 ? 234 LEU   B CB  1 
ATOM   4113 N  N   . VAL   B 1 238 ? -5.13564  41.44645 -12.08610 1.000 126.69600 ? 235 VAL   B N   1 
ATOM   4114 C  CA  . VAL   B 1 238 ? -5.36615  42.62177 -12.91953 1.000 125.23362 ? 235 VAL   B CA  1 
ATOM   4115 C  C   . VAL   B 1 238 ? -5.12500  42.29194 -14.38883 1.000 127.65373 ? 235 VAL   B C   1 
ATOM   4116 O  O   . VAL   B 1 238 ? -6.00849  42.49132 -15.23021 1.000 124.29790 ? 235 VAL   B O   1 
ATOM   4117 C  CB  . VAL   B 1 238 ? -4.48357  43.79999 -12.47341 1.000 132.86515 ? 235 VAL   B CB  1 
ATOM   4118 C  CG1 . VAL   B 1 238 ? -4.64368  44.96885 -13.43805 1.000 127.37659 ? 235 VAL   B CG1 1 
ATOM   4119 C  CG2 . VAL   B 1 238 ? -4.82553  44.21178 -11.04236 1.000 119.55761 ? 235 VAL   B CG2 1 
ATOM   4120 N  N   . GLN   B 1 239 ? -3.93025  41.79591 -14.71306 1.000 133.35677 ? 236 GLN   B N   1 
ATOM   4121 C  CA  . GLN   B 1 239 ? -3.61119  41.38029 -16.07314 1.000 125.89545 ? 236 GLN   B CA  1 
ATOM   4122 C  C   . GLN   B 1 239 ? -2.77350  40.10868 -16.03899 1.000 120.72020 ? 236 GLN   B C   1 
ATOM   4123 O  O   . GLN   B 1 239 ? -1.99637  39.88269 -15.10753 1.000 115.84499 ? 236 GLN   B O   1 
ATOM   4124 C  CB  . GLN   B 1 239 ? -2.87607  42.48067 -16.85869 1.000 122.90818 ? 236 GLN   B CB  1 
ATOM   4125 C  CG  . GLN   B 1 239 ? -2.80978  42.21691 -18.36320 1.000 123.62560 ? 236 GLN   B CG  1 
ATOM   4126 C  CD  . GLN   B 1 239 ? -2.03077  43.27100 -19.12419 1.000 125.62877 ? 236 GLN   B CD  1 
ATOM   4127 O  OE1 . GLN   B 1 239 ? -1.64105  44.29553 -18.56628 1.000 135.83643 ? 236 GLN   B OE1 1 
ATOM   4128 N  NE2 . GLN   B 1 239 ? -1.80231  43.02401 -20.40990 1.000 121.39198 ? 236 GLN   B NE2 1 
ATOM   4129 N  N   . GLN   B 1 240 ? -2.94257  39.27837 -17.06894 1.000 116.37047 ? 237 GLN   B N   1 
ATOM   4130 C  CA  . GLN   B 1 240 ? -2.21673  38.01558 -17.19513 1.000 109.92448 ? 237 GLN   B CA  1 
ATOM   4131 C  C   . GLN   B 1 240 ? -1.88004  37.79798 -18.66450 1.000 105.78700 ? 237 GLN   B C   1 
ATOM   4132 O  O   . GLN   B 1 240 ? -2.78035  37.58192 -19.48135 1.000 110.04167 ? 237 GLN   B O   1 
ATOM   4133 C  CB  . GLN   B 1 240 ? -3.04322  36.84954 -16.65007 1.000 104.06861 ? 237 GLN   B CB  1 
ATOM   4134 C  CG  . GLN   B 1 240 ? -2.38191  35.48555 -16.78366 1.000 97.03005  ? 237 GLN   B CG  1 
ATOM   4135 C  CD  . GLN   B 1 240 ? -1.19544  35.31437 -15.85607 1.000 91.26272  ? 237 GLN   B CD  1 
ATOM   4136 O  OE1 . GLN   B 1 240 ? -1.35727  35.12373 -14.65082 1.000 86.75094  ? 237 GLN   B OE1 1 
ATOM   4137 N  NE2 . GLN   B 1 240 ? 0.00658   35.38720 -16.41362 1.000 99.29032  ? 237 GLN   B NE2 1 
ATOM   4138 N  N   . GLU   B 1 241 ? -0.59304  37.85464 -19.00199 1.000 100.23999 ? 238 GLU   B N   1 
ATOM   4139 C  CA  . GLU   B 1 241 ? -0.11316  37.62310 -20.36467 1.000 104.65209 ? 238 GLU   B CA  1 
ATOM   4140 C  C   . GLU   B 1 241 ? 0.85314   36.44027 -20.33551 1.000 96.49716  ? 238 GLU   B C   1 
ATOM   4141 O  O   . GLU   B 1 241 ? 2.05125   36.61430 -20.10178 1.000 99.45386  ? 238 GLU   B O   1 
ATOM   4142 C  CB  . GLU   B 1 241 ? 0.55961   38.87407 -20.94623 1.000 105.61283 ? 238 GLU   B CB  1 
ATOM   4143 C  CG  . GLU   B 1 241 ? -0.40203  39.96706 -21.38995 1.000 121.92857 ? 238 GLU   B CG  1 
ATOM   4144 C  CD  . GLU   B 1 241 ? 0.21554   40.90846 -22.41267 1.000 137.43021 ? 238 GLU   B CD  1 
ATOM   4145 O  OE1 . GLU   B 1 241 ? 1.28628   40.57351 -22.96427 1.000 135.49386 ? 238 GLU   B OE1 1 
ATOM   4146 O  OE2 . GLU   B 1 241 ? -0.37178  41.98137 -22.66911 1.000 137.30107 ? 238 GLU   B OE2 1 
ATOM   4147 N  N   . SER   B 1 242 ? 0.33330   35.23985 -20.58873 1.000 91.23661  ? 239 SER   B N   1 
ATOM   4148 C  CA  . SER   B 1 242 ? 1.13897   34.02596 -20.56979 1.000 81.13754  ? 239 SER   B CA  1 
ATOM   4149 C  C   . SER   B 1 242 ? 0.37751   32.93584 -21.30319 1.000 83.74630  ? 239 SER   B C   1 
ATOM   4150 O  O   . SER   B 1 242 ? -0.85764  32.97366 -21.34559 1.000 88.99306  ? 239 SER   B O   1 
ATOM   4151 C  CB  . SER   B 1 242 ? 1.44457   33.58141 -19.13478 1.000 79.49188  ? 239 SER   B CB  1 
ATOM   4152 O  OG  . SER   B 1 242 ? 0.25914   33.17666 -18.47766 1.000 78.63650  ? 239 SER   B OG  1 
ATOM   4153 N  N   . PRO   B 1 243 ? 1.07235   31.94538 -21.87114 1.000 82.81989  ? 240 PRO   B N   1 
ATOM   4154 C  CA  . PRO   B 1 243 ? 0.36305   30.88830 -22.60806 1.000 79.75556  ? 240 PRO   B CA  1 
ATOM   4155 C  C   . PRO   B 1 243 ? -0.39433  29.93284 -21.71094 1.000 74.74622  ? 240 PRO   B C   1 
ATOM   4156 O  O   . PRO   B 1 243 ? -1.28306  29.22503 -22.20142 1.000 75.98604  ? 240 PRO   B O   1 
ATOM   4157 C  CB  . PRO   B 1 243 ? 1.48630   30.16183 -23.36381 1.000 77.68558  ? 240 PRO   B CB  1 
ATOM   4158 C  CG  . PRO   B 1 243 ? 2.69362   31.04018 -23.24010 1.000 78.53166  ? 240 PRO   B CG  1 
ATOM   4159 C  CD  . PRO   B 1 243 ? 2.53058   31.78791 -21.96200 1.000 78.34894  ? 240 PRO   B CD  1 
ATOM   4160 N  N   . PHE   B 1 244 ? -0.07543  29.88692 -20.42109 1.000 74.67067  ? 241 PHE   B N   1 
ATOM   4161 C  CA  . PHE   B 1 244 ? -0.77407  29.01836 -19.48462 1.000 74.24058  ? 241 PHE   B CA  1 
ATOM   4162 C  C   . PHE   B 1 244 ? -0.61353  29.59585 -18.08656 1.000 69.45009  ? 241 PHE   B C   1 
ATOM   4163 O  O   . PHE   B 1 244 ? 0.15781   30.53105 -17.86165 1.000 66.37109  ? 241 PHE   B O   1 
ATOM   4164 C  CB  . PHE   B 1 244 ? -0.24860  27.57816 -19.55215 1.000 58.90930  ? 241 PHE   B CB  1 
ATOM   4165 C  CG  . PHE   B 1 244 ? 1.17269   27.42821 -19.08833 1.000 64.51052  ? 241 PHE   B CG  1 
ATOM   4166 C  CD1 . PHE   B 1 244 ? 2.22583   27.60959 -19.96908 1.000 68.65473  ? 241 PHE   B CD1 1 
ATOM   4167 C  CD2 . PHE   B 1 244 ? 1.45640   27.10096 -17.77105 1.000 64.73014  ? 241 PHE   B CD2 1 
ATOM   4168 C  CE1 . PHE   B 1 244 ? 3.53441   27.47379 -19.54339 1.000 72.70150  ? 241 PHE   B CE1 1 
ATOM   4169 C  CE2 . PHE   B 1 244 ? 2.76223   26.96448 -17.33980 1.000 61.96364  ? 241 PHE   B CE2 1 
ATOM   4170 C  CZ  . PHE   B 1 244 ? 3.80250   27.15039 -18.22627 1.000 70.77964  ? 241 PHE   B CZ  1 
ATOM   4171 N  N   . VAL   B 1 245 ? -1.37431  29.03653 -17.15107 1.000 61.95437  ? 242 VAL   B N   1 
ATOM   4172 C  CA  . VAL   B 1 245 ? -1.21939  29.32089 -15.72924 1.000 67.61830  ? 242 VAL   B CA  1 
ATOM   4173 C  C   . VAL   B 1 245 ? -1.38052  28.01062 -14.97411 1.000 72.67311  ? 242 VAL   B C   1 
ATOM   4174 O  O   . VAL   B 1 245 ? -2.22859  27.18239 -15.32133 1.000 72.12946  ? 242 VAL   B O   1 
ATOM   4175 C  CB  . VAL   B 1 245 ? -2.23244  30.36971 -15.21745 1.000 68.32674  ? 242 VAL   B CB  1 
ATOM   4176 C  CG1 . VAL   B 1 245 ? -1.95605  31.74222 -15.82090 1.000 76.06660  ? 242 VAL   B CG1 1 
ATOM   4177 C  CG2 . VAL   B 1 245 ? -3.65774  29.92791 -15.50560 1.000 84.09432  ? 242 VAL   B CG2 1 
ATOM   4178 N  N   . MET   B 1 246 ? -0.55430  27.80658 -13.95845 1.000 71.03051  ? 243 MET   B N   1 
ATOM   4179 C  CA  . MET   B 1 246 ? -0.70121  26.65509 -13.08541 1.000 71.61759  ? 243 MET   B CA  1 
ATOM   4180 C  C   . MET   B 1 246 ? -1.30370  27.13205 -11.77139 1.000 81.51631  ? 243 MET   B C   1 
ATOM   4181 O  O   . MET   B 1 246 ? -0.74041  28.00520 -11.10373 1.000 80.65343  ? 243 MET   B O   1 
ATOM   4182 C  CB  . MET   B 1 246 ? 0.62418   25.92991 -12.84601 1.000 57.80831  ? 243 MET   B CB  1 
ATOM   4183 C  CG  . MET   B 1 246 ? 0.44752   24.76829 -11.87095 1.000 72.02371  ? 243 MET   B CG  1 
ATOM   4184 S  SD  . MET   B 1 246 ? 1.86484   23.69165 -11.60429 1.000 71.72508  ? 243 MET   B SD  1 
ATOM   4185 C  CE  . MET   B 1 246 ? 3.17866   24.81736 -12.00816 1.000 76.71978  ? 243 MET   B CE  1 
ATOM   4186 N  N   . MET   B 1 247 ? -2.45970  26.57890 -11.42598 1.000 79.47734  ? 244 MET   B N   1 
ATOM   4187 C  CA  . MET   B 1 247 ? -3.16087  26.89178 -10.19005 1.000 71.37813  ? 244 MET   B CA  1 
ATOM   4188 C  C   . MET   B 1 247 ? -3.03512  25.67513 -9.28688  1.000 79.75979  ? 244 MET   B C   1 
ATOM   4189 O  O   . MET   B 1 247 ? -3.55344  24.60035 -9.60782  1.000 79.56800  ? 244 MET   B O   1 
ATOM   4190 C  CB  . MET   B 1 247 ? -4.62252  27.23190 -10.46579 1.000 70.46994  ? 244 MET   B CB  1 
ATOM   4191 C  CG  . MET   B 1 247 ? -4.79497  28.32741 -11.49313 1.000 86.08638  ? 244 MET   B CG  1 
ATOM   4192 S  SD  . MET   B 1 247 ? -4.32061  29.92222 -10.82699 1.000 88.35993  ? 244 MET   B SD  1 
ATOM   4193 C  CE  . MET   B 1 247 ? -5.40864  29.95446 -9.40872  1.000 102.94871 ? 244 MET   B CE  1 
ATOM   4194 N  N   . SER   B 1 248 ? -2.32674  25.83942 -8.17544  1.000 86.83600  ? 245 SER   B N   1 
ATOM   4195 C  CA  . SER   B 1 248 ? -2.10524  24.76546 -7.22414  1.000 82.26443  ? 245 SER   B CA  1 
ATOM   4196 C  C   . SER   B 1 248 ? -2.72088  25.12945 -5.88112  1.000 88.57992  ? 245 SER   B C   1 
ATOM   4197 O  O   . SER   B 1 248 ? -2.90682  26.30439 -5.55267  1.000 91.60565  ? 245 SER   B O   1 
ATOM   4198 C  CB  . SER   B 1 248 ? -0.61126  24.46462 -7.05534  1.000 73.12267  ? 245 SER   B CB  1 
ATOM   4199 O  OG  . SER   B 1 248 ? -0.05119  23.96515 -8.25433  1.000 79.54851  ? 245 SER   B OG  1 
ATOM   4200 N  N   . ALA   B 1 249 ? -3.03349  24.09367 -5.10640  1.000 85.30143  ? 246 ALA   B N   1 
ATOM   4201 C  CA  . ALA   B 1 249 ? -3.62319  24.24046 -3.78352  1.000 87.28259  ? 246 ALA   B CA  1 
ATOM   4202 C  C   . ALA   B 1 249 ? -3.47466  22.91269 -3.06163  1.000 84.41188  ? 246 ALA   B C   1 
ATOM   4203 O  O   . ALA   B 1 249 ? -3.35788  21.87199 -3.71914  1.000 85.89076  ? 246 ALA   B O   1 
ATOM   4204 C  CB  . ALA   B 1 249 ? -5.10221  24.64625 -3.87357  1.000 86.36440  ? 246 ALA   B CB  1 
ATOM   4205 N  N   . PRO   B 1 250 ? -3.45366  22.90794 -1.73065  1.000 87.65586  ? 247 PRO   B N   1 
ATOM   4206 C  CA  . PRO   B 1 250 ? -3.34777  21.64005 -0.99796  1.000 86.95135  ? 247 PRO   B CA  1 
ATOM   4207 C  C   . PRO   B 1 250 ? -4.50347  20.72158 -1.34983  1.000 80.83604  ? 247 PRO   B C   1 
ATOM   4208 O  O   . PRO   B 1 250 ? -5.63626  21.18894 -1.54260  1.000 77.81314  ? 247 PRO   B O   1 
ATOM   4209 C  CB  . PRO   B 1 250 ? -3.39597  22.07396 0.47463   1.000 83.32258  ? 247 PRO   B CB  1 
ATOM   4210 C  CG  . PRO   B 1 250 ? -2.93454  23.49971 0.45999   1.000 88.72751  ? 247 PRO   B CG  1 
ATOM   4211 C  CD  . PRO   B 1 250 ? -3.47399  24.06852 -0.82243  1.000 91.58294  ? 247 PRO   B CD  1 
ATOM   4212 N  N   . PRO   B 1 251 ? -4.24935  19.41772 -1.46367  1.000 74.26534  ? 248 PRO   B N   1 
ATOM   4213 C  CA  . PRO   B 1 251 ? -5.26798  18.49229 -1.97987  1.000 77.18677  ? 248 PRO   B CA  1 
ATOM   4214 C  C   . PRO   B 1 251 ? -6.61296  18.63595 -1.28549  1.000 80.23095  ? 248 PRO   B C   1 
ATOM   4215 O  O   . PRO   B 1 251 ? -6.70954  18.61697 -0.05787  1.000 92.12714  ? 248 PRO   B O   1 
ATOM   4216 C  CB  . PRO   B 1 251 ? -4.64752  17.11554 -1.72327  1.000 71.14021  ? 248 PRO   B CB  1 
ATOM   4217 C  CG  . PRO   B 1 251 ? -3.19285  17.35859 -1.77631  1.000 78.76390  ? 248 PRO   B CG  1 
ATOM   4218 C  CD  . PRO   B 1 251 ? -2.97184  18.73561 -1.19836  1.000 81.06382  ? 248 PRO   B CD  1 
ATOM   4219 N  N   . ALA   B 1 252 ? -7.65674  18.78231 -2.09586  1.000 93.75646  ? 249 ALA   B N   1 
ATOM   4220 C  CA  . ALA   B 1 252 ? -9.01515  18.94882 -1.61092  1.000 87.48576  ? 249 ALA   B CA  1 
ATOM   4221 C  C   . ALA   B 1 252 ? -9.97256  18.39268 -2.65327  1.000 93.00761  ? 249 ALA   B C   1 
ATOM   4222 O  O   . ALA   B 1 252 ? -9.67857  18.40568 -3.85239  1.000 99.24007  ? 249 ALA   B O   1 
ATOM   4223 C  CB  . ALA   B 1 252 ? -9.33468  20.42145 -1.32705  1.000 83.26113  ? 249 ALA   B CB  1 
ATOM   4224 N  N   . GLN   B 1 253 ? -11.11678 17.89453 -2.18558  1.000 87.23112  ? 250 GLN   B N   1 
ATOM   4225 C  CA  . GLN   B 1 253 ? -12.16209 17.45645 -3.10117  1.000 76.73098  ? 250 GLN   B CA  1 
ATOM   4226 C  C   . GLN   B 1 253 ? -12.61756 18.62279 -3.96523  1.000 84.54356  ? 250 GLN   B C   1 
ATOM   4227 O  O   . GLN   B 1 253 ? -12.93878 19.70165 -3.45625  1.000 71.08674  ? 250 GLN   B O   1 
ATOM   4228 C  CB  . GLN   B 1 253 ? -13.34226 16.86937 -2.33005  1.000 61.81430  ? 250 GLN   B CB  1 
ATOM   4229 C  CG  . GLN   B 1 253 ? -13.08513 15.48157 -1.77301  1.000 76.89479  ? 250 GLN   B CG  1 
ATOM   4230 C  CD  . GLN   B 1 253 ? -13.16587 14.40444 -2.83606  1.000 81.76177  ? 250 GLN   B CD  1 
ATOM   4231 O  OE1 . GLN   B 1 253 ? -13.98366 14.48257 -3.75248  1.000 92.12294  ? 250 GLN   B OE1 1 
ATOM   4232 N  NE2 . GLN   B 1 253 ? -12.31672 13.39025 -2.71902  1.000 79.27051  ? 250 GLN   B NE2 1 
ATOM   4233 N  N   . TYR   B 1 254 ? -12.63934 18.39604 -5.27838  1.000 82.94367  ? 251 TYR   B N   1 
ATOM   4234 C  CA  . TYR   B 1 254 ? -12.87318 19.44105 -6.26203  1.000 78.60980  ? 251 TYR   B CA  1 
ATOM   4235 C  C   . TYR   B 1 254 ? -13.67529 18.85859 -7.41478  1.000 79.17051  ? 251 TYR   B C   1 
ATOM   4236 O  O   . TYR   B 1 254 ? -13.56395 17.66884 -7.72771  1.000 73.85520  ? 251 TYR   B O   1 
ATOM   4237 C  CB  . TYR   B 1 254 ? -11.54212 20.01806 -6.76544  1.000 77.04197  ? 251 TYR   B CB  1 
ATOM   4238 C  CG  . TYR   B 1 254 ? -11.64707 21.31244 -7.53703  1.000 76.82213  ? 251 TYR   B CG  1 
ATOM   4239 C  CD1 . TYR   B 1 254 ? -11.96666 22.50079 -6.89630  1.000 69.94654  ? 251 TYR   B CD1 1 
ATOM   4240 C  CD2 . TYR   B 1 254 ? -11.39015 21.35223 -8.90148  1.000 74.98542  ? 251 TYR   B CD2 1 
ATOM   4241 C  CE1 . TYR   B 1 254 ? -12.05166 23.68927 -7.59586  1.000 80.01197  ? 251 TYR   B CE1 1 
ATOM   4242 C  CE2 . TYR   B 1 254 ? -11.47178 22.53584 -9.60984  1.000 75.11202  ? 251 TYR   B CE2 1 
ATOM   4243 C  CZ  . TYR   B 1 254 ? -11.80255 23.70181 -8.95104  1.000 81.27217  ? 251 TYR   B CZ  1 
ATOM   4244 O  OH  . TYR   B 1 254 ? -11.88634 24.88689 -9.64645  1.000 88.75661  ? 251 TYR   B OH  1 
ATOM   4245 N  N   . GLU   B 1 255 ? -14.49821 19.70062 -8.03742  1.000 79.76827  ? 252 GLU   B N   1 
ATOM   4246 C  CA  . GLU   B 1 255 ? -15.31305 19.29807 -9.17730  1.000 86.71998  ? 252 GLU   B CA  1 
ATOM   4247 C  C   . GLU   B 1 255 ? -14.72588 19.91732 -10.43862 1.000 84.36209  ? 252 GLU   B C   1 
ATOM   4248 O  O   . GLU   B 1 255 ? -14.72085 21.14551 -10.58978 1.000 81.63764  ? 252 GLU   B O   1 
ATOM   4249 C  CB  . GLU   B 1 255 ? -16.77040 19.71858 -9.00130  1.000 86.83718  ? 252 GLU   B CB  1 
ATOM   4250 C  CG  . GLU   B 1 255 ? -17.71927 18.97266 -9.93006  1.000 100.39788 ? 252 GLU   B CG  1 
ATOM   4251 C  CD  . GLU   B 1 255 ? -19.07435 19.63778 -10.05376 1.000 107.24353 ? 252 GLU   B CD  1 
ATOM   4252 O  OE1 . GLU   B 1 255 ? -19.17831 20.84220 -9.74133  1.000 110.41575 ? 252 GLU   B OE1 1 
ATOM   4253 O  OE2 . GLU   B 1 255 ? -20.03552 18.95322 -10.46743 1.000 101.31240 ? 252 GLU   B OE2 1 
ATOM   4254 N  N   . LEU   B 1 256 ? -14.23604 19.06733 -11.33674 1.000 81.01213  ? 253 LEU   B N   1 
ATOM   4255 C  CA  . LEU   B 1 256 ? -13.72298 19.50290 -12.62725 1.000 80.31385  ? 253 LEU   B CA  1 
ATOM   4256 C  C   . LEU   B 1 256 ? -14.83160 19.40972 -13.66773 1.000 82.50353  ? 253 LEU   B C   1 
ATOM   4257 O  O   . LEU   B 1 256 ? -15.45451 18.35365 -13.82639 1.000 83.58879  ? 253 LEU   B O   1 
ATOM   4258 C  CB  . LEU   B 1 256 ? -12.52413 18.65014 -13.04486 1.000 75.43785  ? 253 LEU   B CB  1 
ATOM   4259 C  CG  . LEU   B 1 256 ? -11.27680 18.73400 -12.16280 1.000 63.00776  ? 253 LEU   B CG  1 
ATOM   4260 C  CD1 . LEU   B 1 256 ? -10.29387 17.62907 -12.51409 1.000 59.12807  ? 253 LEU   B CD1 1 
ATOM   4261 C  CD2 . LEU   B 1 256 ? -10.62058 20.09774 -12.29783 1.000 53.55621  ? 253 LEU   B CD2 1 
ATOM   4262 N  N   . LYS   B 1 257 ? -15.08028 20.51597 -14.36470 1.000 76.08241  ? 254 LYS   B N   1 
ATOM   4263 C  CA  . LYS   B 1 257 ? -16.11651 20.59314 -15.38676 1.000 82.78982  ? 254 LYS   B CA  1 
ATOM   4264 C  C   . LYS   B 1 257 ? -15.47987 20.59626 -16.77103 1.000 78.83015  ? 254 LYS   B C   1 
ATOM   4265 O  O   . LYS   B 1 257 ? -14.51870 21.33414 -17.01599 1.000 69.55627  ? 254 LYS   B O   1 
ATOM   4266 C  CB  . LYS   B 1 257 ? -16.98423 21.84188 -15.19722 1.000 84.01308  ? 254 LYS   B CB  1 
ATOM   4267 C  CG  . LYS   B 1 257 ? -17.61543 21.97535 -13.80795 1.000 98.18866  ? 254 LYS   B CG  1 
ATOM   4268 C  CD  . LYS   B 1 257 ? -19.06304 21.47741 -13.77000 1.000 101.83569 ? 254 LYS   B CD  1 
ATOM   4269 C  CE  . LYS   B 1 257 ? -19.15454 19.95601 -13.70296 1.000 98.92384  ? 254 LYS   B CE  1 
ATOM   4270 N  NZ  . LYS   B 1 257 ? -20.53027 19.49417 -13.36733 1.000 101.35771 ? 254 LYS   B NZ  1 
ATOM   4271 N  N   . HIS   B 1 258 ? -16.01852 19.76709 -17.66570 1.000 81.36325  ? 255 HIS   B N   1 
ATOM   4272 C  CA  . HIS   B 1 258 ? -15.49854 19.64841 -19.02327 1.000 72.52798  ? 255 HIS   B CA  1 
ATOM   4273 C  C   . HIS   B 1 258 ? -15.44995 21.00245 -19.72047 1.000 73.84829  ? 255 HIS   B C   1 
ATOM   4274 O  O   . HIS   B 1 258 ? -16.40701 21.77828 -19.66941 1.000 75.50705  ? 255 HIS   B O   1 
ATOM   4275 C  CB  . HIS   B 1 258 ? -16.36718 18.67426 -19.82458 1.000 71.61385  ? 255 HIS   B CB  1 
ATOM   4276 C  CG  . HIS   B 1 258 ? -16.20160 18.79730 -21.30769 1.000 88.09792  ? 255 HIS   B CG  1 
ATOM   4277 N  ND1 . HIS   B 1 258 ? -17.10517 19.47222 -22.10149 1.000 99.46535  ? 255 HIS   B ND1 1 
ATOM   4278 C  CD2 . HIS   B 1 258 ? -15.24304 18.32980 -22.14286 1.000 82.25282  ? 255 HIS   B CD2 1 
ATOM   4279 C  CE1 . HIS   B 1 258 ? -16.70498 19.42372 -23.35986 1.000 90.49110  ? 255 HIS   B CE1 1 
ATOM   4280 N  NE2 . HIS   B 1 258 ? -15.57923 18.73398 -23.41284 1.000 87.70527  ? 255 HIS   B NE2 1 
ATOM   4281 N  N   . GLY   B 1 259 ? -14.32058 21.28420 -20.36661 1.000 64.88204  ? 256 GLY   B N   1 
ATOM   4282 C  CA  . GLY   B 1 259 ? -14.16685 22.49204 -21.14627 1.000 60.79601  ? 256 GLY   B CA  1 
ATOM   4283 C  C   . GLY   B 1 259 ? -13.77410 23.73098 -20.37291 1.000 66.25264  ? 256 GLY   B C   1 
ATOM   4284 O  O   . GLY   B 1 259 ? -13.59062 24.78912 -20.98955 1.000 64.93440  ? 256 GLY   B O   1 
ATOM   4285 N  N   . THR   B 1 260 ? -13.63570 23.64550 -19.05168 1.000 73.55020  ? 257 THR   B N   1 
ATOM   4286 C  CA  . THR   B 1 260 ? -13.25475 24.79252 -18.23758 1.000 74.50637  ? 257 THR   B CA  1 
ATOM   4287 C  C   . THR   B 1 260 ? -11.79033 24.77317 -17.82105 1.000 71.89158  ? 257 THR   B C   1 
ATOM   4288 O  O   . THR   B 1 260 ? -11.32126 25.73997 -17.21407 1.000 74.68037  ? 257 THR   B O   1 
ATOM   4289 C  CB  . THR   B 1 260 ? -14.14269 24.87141 -16.99140 1.000 75.65259  ? 257 THR   B CB  1 
ATOM   4290 O  OG1 . THR   B 1 260 ? -14.02586 23.65443 -16.23951 1.000 77.67192  ? 257 THR   B OG1 1 
ATOM   4291 C  CG2 . THR   B 1 260 ? -15.59174 25.08582 -17.39238 1.000 67.01765  ? 257 THR   B CG2 1 
ATOM   4292 N  N   . PHE   B 1 261 ? -11.05958 23.70916 -18.13958 1.000 69.98259  ? 258 PHE   B N   1 
ATOM   4293 C  CA  . PHE   B 1 261 ? -9.65410  23.59949 -17.78350 1.000 66.30248  ? 258 PHE   B CA  1 
ATOM   4294 C  C   . PHE   B 1 261 ? -8.94893  22.77657 -18.85210 1.000 65.16417  ? 258 PHE   B C   1 
ATOM   4295 O  O   . PHE   B 1 261 ? -9.58490  22.12056 -19.68049 1.000 72.27447  ? 258 PHE   B O   1 
ATOM   4296 C  CB  . PHE   B 1 261 ? -9.47706  22.95878 -16.40326 1.000 54.81653  ? 258 PHE   B CB  1 
ATOM   4297 C  CG  . PHE   B 1 261 ? -9.82315  21.49283 -16.36606 1.000 54.10732  ? 258 PHE   B CG  1 
ATOM   4298 C  CD1 . PHE   B 1 261 ? -11.14398 21.07372 -16.40455 1.000 61.64451  ? 258 PHE   B CD1 1 
ATOM   4299 C  CD2 . PHE   B 1 261 ? -8.82706  20.53342 -16.28119 1.000 58.34110  ? 258 PHE   B CD2 1 
ATOM   4300 C  CE1 . PHE   B 1 261 ? -11.46422 19.72353 -16.36908 1.000 57.21973  ? 258 PHE   B CE1 1 
ATOM   4301 C  CE2 . PHE   B 1 261 ? -9.14090  19.18193 -16.24343 1.000 55.77761  ? 258 PHE   B CE2 1 
ATOM   4302 C  CZ  . PHE   B 1 261 ? -10.46079 18.77823 -16.28726 1.000 52.93621  ? 258 PHE   B CZ  1 
ATOM   4303 N  N   . THR   B 1 262 ? -7.61763  22.80651 -18.81945 1.000 59.71652  ? 259 THR   B N   1 
ATOM   4304 C  CA  . THR   B 1 262 ? -6.81914  22.00286 -19.74034 1.000 45.29624  ? 259 THR   B CA  1 
ATOM   4305 C  C   . THR   B 1 262 ? -6.51595  20.62654 -19.14924 1.000 54.42273  ? 259 THR   B C   1 
ATOM   4306 O  O   . THR   B 1 262 ? -6.91018  19.60152 -19.71480 1.000 52.40365  ? 259 THR   B O   1 
ATOM   4307 C  CB  . THR   B 1 262 ? -5.52636  22.74210 -20.09959 1.000 56.46173  ? 259 THR   B CB  1 
ATOM   4308 O  OG1 . THR   B 1 262 ? -5.84464  24.04397 -20.61034 1.000 60.98420  ? 259 THR   B OG1 1 
ATOM   4309 C  CG2 . THR   B 1 262 ? -4.74675  21.96842 -21.14818 1.000 52.71978  ? 259 THR   B CG2 1 
ATOM   4310 N  N   . CYS   B 1 263 ? -5.82503  20.59018 -18.00985 1.000 64.62726  ? 260 CYS   B N   1 
ATOM   4311 C  CA  . CYS   B 1 263 ? -5.54663  19.33779 -17.31862 1.000 65.90461  ? 260 CYS   B CA  1 
ATOM   4312 C  C   . CYS   B 1 263 ? -5.34256  19.62144 -15.83584 1.000 65.47974  ? 260 CYS   B C   1 
ATOM   4313 O  O   . CYS   B 1 263 ? -5.21930  20.77410 -15.40943 1.000 67.78226  ? 260 CYS   B O   1 
ATOM   4314 C  CB  . CYS   B 1 263 ? -4.32997  18.61539 -17.91187 1.000 60.18913  ? 260 CYS   B CB  1 
ATOM   4315 S  SG  . CYS   B 1 263 ? -2.79255  19.55946 -17.87988 1.000 64.43411  ? 260 CYS   B SG  1 
ATOM   4316 N  N   . ALA   B 1 264 ? -5.31068  18.54899 -15.04699 1.000 61.30591  ? 261 ALA   B N   1 
ATOM   4317 C  CA  . ALA   B 1 264 ? -5.25527  18.68107 -13.60035 1.000 63.91962  ? 261 ALA   B CA  1 
ATOM   4318 C  C   . ALA   B 1 264 ? -4.53571  17.48156 -13.00256 1.000 67.13366  ? 261 ALA   B C   1 
ATOM   4319 O  O   . ALA   B 1 264 ? -4.43931  16.41565 -13.61804 1.000 59.64372  ? 261 ALA   B O   1 
ATOM   4320 C  CB  . ALA   B 1 264 ? -6.65762  18.81961 -12.99767 1.000 69.74961  ? 261 ALA   B CB  1 
ATOM   4321 N  N   . SER   B 1 265 ? -4.03004  17.67630 -11.78572 1.000 80.69305  ? 262 SER   B N   1 
ATOM   4322 C  CA  . SER   B 1 265 ? -3.33455  16.64356 -11.02682 1.000 74.49819  ? 262 SER   B CA  1 
ATOM   4323 C  C   . SER   B 1 265 ? -4.19065  16.19670 -9.84924  1.000 76.94461  ? 262 SER   B C   1 
ATOM   4324 O  O   . SER   B 1 265 ? -4.64008  17.02675 -9.05340  1.000 73.25607  ? 262 SER   B O   1 
ATOM   4325 C  CB  . SER   B 1 265 ? -1.98010  17.15010 -10.52293 1.000 71.28890  ? 262 SER   B CB  1 
ATOM   4326 O  OG  . SER   B 1 265 ? -1.15881  17.58487 -11.58948 1.000 84.49967  ? 262 SER   B OG  1 
ATOM   4327 N  N   . GLU   B 1 266 ? -4.41468  14.89009 -9.75020  1.000 78.30232  ? 263 GLU   B N   1 
ATOM   4328 C  CA  . GLU   B 1 266 ? -5.14155  14.28832 -8.64011  1.000 80.04081  ? 263 GLU   B CA  1 
ATOM   4329 C  C   . GLU   B 1 266 ? -4.15982  13.59365 -7.70480  1.000 87.51831  ? 263 GLU   B C   1 
ATOM   4330 O  O   . GLU   B 1 266 ? -3.27325  12.86629 -8.16351  1.000 84.14484  ? 263 GLU   B O   1 
ATOM   4331 C  CB  . GLU   B 1 266 ? -6.17392  13.27960 -9.14248  1.000 78.50572  ? 263 GLU   B CB  1 
ATOM   4332 C  CG  . GLU   B 1 266 ? -6.93338  12.58060 -8.02575  1.000 86.80227  ? 263 GLU   B CG  1 
ATOM   4333 C  CD  . GLU   B 1 266 ? -7.20331  11.11808 -8.32111  1.000 96.15895  ? 263 GLU   B CD  1 
ATOM   4334 O  OE1 . GLU   B 1 266 ? -6.29542  10.29436 -8.08203  1.000 99.19421  ? 263 GLU   B OE1 1 
ATOM   4335 O  OE2 . GLU   B 1 266 ? -8.31541  10.79011 -8.78945  1.000 92.34789  ? 263 GLU   B OE2 1 
ATOM   4336 N  N   . TYR   B 1 267 ? -4.31759  13.81646 -6.39913  1.000 94.18365  ? 264 TYR   B N   1 
ATOM   4337 C  CA  . TYR   B 1 267 ? -3.43772  13.22460 -5.39708  1.000 89.14039  ? 264 TYR   B CA  1 
ATOM   4338 C  C   . TYR   B 1 267 ? -4.26039  12.49703 -4.34262  1.000 92.52796  ? 264 TYR   B C   1 
ATOM   4339 O  O   . TYR   B 1 267 ? -5.16205  13.08454 -3.73567  1.000 81.26560  ? 264 TYR   B O   1 
ATOM   4340 C  CB  . TYR   B 1 267 ? -2.55280  14.28914 -4.73867  1.000 81.60939  ? 264 TYR   B CB  1 
ATOM   4341 C  CG  . TYR   B 1 267 ? -1.50074  13.71166 -3.81690  1.000 99.96040  ? 264 TYR   B CG  1 
ATOM   4342 C  CD1 . TYR   B 1 267 ? -0.33701  13.15090 -4.32904  1.000 92.09326  ? 264 TYR   B CD1 1 
ATOM   4343 C  CD2 . TYR   B 1 267 ? -1.66465  13.73329 -2.43551  1.000 97.54496  ? 264 TYR   B CD2 1 
ATOM   4344 C  CE1 . TYR   B 1 267 ? 0.63186   12.61939 -3.49399  1.000 96.18986  ? 264 TYR   B CE1 1 
ATOM   4345 C  CE2 . TYR   B 1 267 ? -0.69813  13.20516 -1.59118  1.000 93.08592  ? 264 TYR   B CE2 1 
ATOM   4346 C  CZ  . TYR   B 1 267 ? 0.44837   12.65007 -2.12750  1.000 98.11672  ? 264 TYR   B CZ  1 
ATOM   4347 O  OH  . TYR   B 1 267 ? 1.41730   12.12293 -1.30209  1.000 86.95529  ? 264 TYR   B OH  1 
ATOM   4348 N  N   . THR   B 1 268 ? -3.94376  11.22218 -4.12617  1.000 93.41979  ? 265 THR   B N   1 
ATOM   4349 C  CA  . THR   B 1 268 ? -4.62237  10.38756 -3.14215  1.000 93.69546  ? 265 THR   B CA  1 
ATOM   4350 C  C   . THR   B 1 268 ? -3.58855  9.82462  -2.17759  1.000 100.96034 ? 265 THR   B C   1 
ATOM   4351 O  O   . THR   B 1 268 ? -2.67832  9.10102  -2.59386  1.000 102.73909 ? 265 THR   B O   1 
ATOM   4352 C  CB  . THR   B 1 268 ? -5.39302  9.25178  -3.81970  1.000 95.20087  ? 265 THR   B CB  1 
ATOM   4353 O  OG1 . THR   B 1 268 ? -6.34590  9.80086  -4.73807  1.000 109.00992 ? 265 THR   B OG1 1 
ATOM   4354 C  CG2 . THR   B 1 268 ? -6.11533  8.39925  -2.78526  1.000 94.75655  ? 265 THR   B CG2 1 
ATOM   4355 N  N   . GLY   B 1 269 ? -3.73384  10.14903 -0.89125  1.000 106.07739 ? 266 GLY   B N   1 
ATOM   4356 C  CA  . GLY   B 1 269 ? -2.86256  9.64870  0.14723   1.000 104.12741 ? 266 GLY   B CA  1 
ATOM   4357 C  C   . GLY   B 1 269 ? -2.44372  10.76163 1.08388   1.000 102.68130 ? 266 GLY   B C   1 
ATOM   4358 O  O   . GLY   B 1 269 ? -3.07257  11.82481 1.14239   1.000 98.51449  ? 266 GLY   B O   1 
ATOM   4359 N  N   . ASN   B 1 270 ? -1.36448  10.51462 1.81876   1.000 97.32319  ? 267 ASN   B N   1 
ATOM   4360 C  CA  . ASN   B 1 270 ? -0.86998  11.44247 2.82457   1.000 105.30139 ? 267 ASN   B CA  1 
ATOM   4361 C  C   . ASN   B 1 270 ? 0.26455   12.29787 2.27112   1.000 97.84812  ? 267 ASN   B C   1 
ATOM   4362 O  O   . ASN   B 1 270 ? 0.80793   12.04529 1.19359   1.000 97.62958  ? 267 ASN   B O   1 
ATOM   4363 C  CB  . ASN   B 1 270 ? -0.40664  10.68335 4.07157   1.000 101.79777 ? 267 ASN   B CB  1 
ATOM   4364 C  CG  . ASN   B 1 270 ? -1.46042  9.73185  4.59315   1.000 114.03301 ? 267 ASN   B CG  1 
ATOM   4365 O  OD1 . ASN   B 1 270 ? -2.60861  10.12102 4.81131   1.000 113.73786 ? 267 ASN   B OD1 1 
ATOM   4366 N  ND2 . ASN   B 1 270 ? -1.07846  8.47508  4.79296   1.000 112.75695 ? 267 ASN   B ND2 1 
ATOM   4367 N  N   . TYR   B 1 271 ? 0.60991   13.33053 3.03606   1.000 96.74082  ? 268 TYR   B N   1 
ATOM   4368 C  CA  . TYR   B 1 271 ? 1.74676   14.18609 2.71952   1.000 91.11837  ? 268 TYR   B CA  1 
ATOM   4369 C  C   . TYR   B 1 271 ? 3.00928   13.33352 2.59287   1.000 89.52727  ? 268 TYR   B C   1 
ATOM   4370 O  O   . TYR   B 1 271 ? 3.35435   12.58434 3.51197   1.000 96.83797  ? 268 TYR   B O   1 
ATOM   4371 C  CB  . TYR   B 1 271 ? 1.89067   15.24368 3.81553   1.000 91.09063  ? 268 TYR   B CB  1 
ATOM   4372 C  CG  . TYR   B 1 271 ? 2.68218   16.48033 3.45217   1.000 92.49070  ? 268 TYR   B CG  1 
ATOM   4373 C  CD1 . TYR   B 1 271 ? 4.00270   16.40243 3.04697   1.000 94.70185  ? 268 TYR   B CD1 1 
ATOM   4374 C  CD2 . TYR   B 1 271 ? 2.10152   17.73825 3.54423   1.000 97.10906  ? 268 TYR   B CD2 1 
ATOM   4375 C  CE1 . TYR   B 1 271 ? 4.72324   17.53980 2.72354   1.000 101.32927 ? 268 TYR   B CE1 1 
ATOM   4376 C  CE2 . TYR   B 1 271 ? 2.80979   18.88042 3.22682   1.000 106.38363 ? 268 TYR   B CE2 1 
ATOM   4377 C  CZ  . TYR   B 1 271 ? 4.11999   18.77782 2.81676   1.000 103.54595 ? 268 TYR   B CZ  1 
ATOM   4378 O  OH  . TYR   B 1 271 ? 4.82217   19.92000 2.50020   1.000 91.68709  ? 268 TYR   B OH  1 
ATOM   4379 N  N   . GLN   B 1 272 ? 3.67592   13.43149 1.43930   1.000 78.29717  ? 269 GLN   B N   1 
ATOM   4380 C  CA  . GLN   B 1 272 ? 4.88624   12.68149 1.09424   1.000 65.14028  ? 269 GLN   B CA  1 
ATOM   4381 C  C   . GLN   B 1 272 ? 4.64558   11.18376 0.94208   1.000 76.21475  ? 269 GLN   B C   1 
ATOM   4382 O  O   . GLN   B 1 272 ? 5.60004   10.40148 1.00087   1.000 79.82272  ? 269 GLN   B O   1 
ATOM   4383 C  CB  . GLN   B 1 272 ? 6.02640   12.90619 2.09458   1.000 75.83733  ? 269 GLN   B CB  1 
ATOM   4384 C  CG  . GLN   B 1 272 ? 6.41484   14.34958 2.29741   1.000 81.68828  ? 269 GLN   B CG  1 
ATOM   4385 C  CD  . GLN   B 1 272 ? 7.83313   14.65074 1.85747   1.000 86.30636  ? 269 GLN   B CD  1 
ATOM   4386 O  OE1 . GLN   B 1 272 ? 8.42992   13.90913 1.07317   1.000 80.85495  ? 269 GLN   B OE1 1 
ATOM   4387 N  NE2 . GLN   B 1 272 ? 8.38340   15.74702 2.36591   1.000 85.00949  ? 269 GLN   B NE2 1 
ATOM   4388 N  N   . CYS   B 1 273 ? 3.39498   10.75400 0.73842   1.000 85.86423  ? 270 CYS   B N   1 
ATOM   4389 C  CA  . CYS   B 1 273 ? 3.12792   9.35507  0.38908   1.000 96.92272  ? 270 CYS   B CA  1 
ATOM   4390 C  C   . CYS   B 1 273 ? 1.74839   9.27152  -0.26742  1.000 100.69705 ? 270 CYS   B C   1 
ATOM   4391 O  O   . CYS   B 1 273 ? 0.73121   9.25335  0.43142   1.000 103.24846 ? 270 CYS   B O   1 
ATOM   4392 C  CB  . CYS   B 1 273 ? 3.21814   8.44662  1.60452   1.000 80.80659  ? 270 CYS   B CB  1 
ATOM   4393 S  SG  . CYS   B 1 273 ? 3.71793   6.75448  1.19107   1.000 91.80202  ? 270 CYS   B SG  1 
ATOM   4394 N  N   . GLY   B 1 274 ? 1.72910   9.21520  -1.59761  1.000 93.90108  ? 271 GLY   B N   1 
ATOM   4395 C  CA  . GLY   B 1 274 ? 0.46563   9.16480  -2.31144  1.000 97.81190  ? 271 GLY   B CA  1 
ATOM   4396 C  C   . GLY   B 1 274 ? 0.64974   8.79384  -3.76622  1.000 100.46428 ? 271 GLY   B C   1 
ATOM   4397 O  O   . GLY   B 1 274 ? 1.77020   8.69212  -4.27633  1.000 88.48035  ? 271 GLY   B O   1 
ATOM   4398 N  N   . HIS   B 1 275 ? -0.48752  8.58889  -4.42710  1.000 103.43729 ? 272 HIS   B N   1 
ATOM   4399 C  CA  . HIS   B 1 275 ? -0.55131  8.26575  -5.84378  1.000 94.60329  ? 272 HIS   B CA  1 
ATOM   4400 C  C   . HIS   B 1 275 ? -1.07733  9.47851  -6.59726  1.000 93.62252  ? 272 HIS   B C   1 
ATOM   4401 O  O   . HIS   B 1 275 ? -2.02748  10.13385 -6.15573  1.000 90.11334  ? 272 HIS   B O   1 
ATOM   4402 C  CB  . HIS   B 1 275 ? -1.45481  7.04647  -6.08502  1.000 88.26371  ? 272 HIS   B CB  1 
ATOM   4403 C  CG  . HIS   B 1 275 ? -1.38345  6.48420  -7.47424  1.000 92.83782  ? 272 HIS   B CG  1 
ATOM   4404 N  ND1 . HIS   B 1 275 ? -0.64652  7.06308  -8.48629  1.000 102.46251 ? 272 HIS   B ND1 1 
ATOM   4405 C  CD2 . HIS   B 1 275 ? -1.96131  5.38470  -8.01502  1.000 95.84314  ? 272 HIS   B CD2 1 
ATOM   4406 C  CE1 . HIS   B 1 275 ? -0.77670  6.34789  -9.58991  1.000 98.10420  ? 272 HIS   B CE1 1 
ATOM   4407 N  NE2 . HIS   B 1 275 ? -1.56968  5.32378  -9.33069  1.000 92.12033  ? 272 HIS   B NE2 1 
ATOM   4408 N  N   . TYR   B 1 276 ? -0.44957  9.77548  -7.72703  1.000 92.42215  ? 273 TYR   B N   1 
ATOM   4409 C  CA  . TYR   B 1 276 ? -0.87059  10.85704 -8.60123  1.000 80.81375  ? 273 TYR   B CA  1 
ATOM   4410 C  C   . TYR   B 1 276 ? -1.66275  10.28949 -9.77056  1.000 80.82809  ? 273 TYR   B C   1 
ATOM   4411 O  O   . TYR   B 1 276 ? -1.31492  9.23998  -10.32116 1.000 84.07428  ? 273 TYR   B O   1 
ATOM   4412 C  CB  . TYR   B 1 276 ? 0.33194   11.63825 -9.12927  1.000 76.27326  ? 273 TYR   B CB  1 
ATOM   4413 C  CG  . TYR   B 1 276 ? 0.70909   12.89906 -8.37702  1.000 66.58088  ? 273 TYR   B CG  1 
ATOM   4414 C  CD1 . TYR   B 1 276 ? -0.08825  14.03460 -8.45006  1.000 66.65027  ? 273 TYR   B CD1 1 
ATOM   4415 C  CD2 . TYR   B 1 276 ? 1.89623   12.97849 -7.65703  1.000 59.56661  ? 273 TYR   B CD2 1 
ATOM   4416 C  CE1 . TYR   B 1 276 ? 0.26453   15.20314 -7.79724  1.000 67.06735  ? 273 TYR   B CE1 1 
ATOM   4417 C  CE2 . TYR   B 1 276 ? 2.26024   14.14611 -7.00042  1.000 54.47154  ? 273 TYR   B CE2 1 
ATOM   4418 C  CZ  . TYR   B 1 276 ? 1.43814   15.25527 -7.07531  1.000 68.32060  ? 273 TYR   B CZ  1 
ATOM   4419 O  OH  . TYR   B 1 276 ? 1.78252   16.42316 -6.43183  1.000 65.15000  ? 273 TYR   B OH  1 
ATOM   4420 N  N   . LYS   B 1 277 ? -2.72286  10.99573 -10.15128 1.000 78.79702  ? 274 LYS   B N   1 
ATOM   4421 C  CA  . LYS   B 1 277 ? -3.48374  10.68445 -11.34983 1.000 76.46992  ? 274 LYS   B CA  1 
ATOM   4422 C  C   . LYS   B 1 277 ? -3.64150  11.95255 -12.17441 1.000 77.39708  ? 274 LYS   B C   1 
ATOM   4423 O  O   . LYS   B 1 277 ? -3.67667  13.06337 -11.63532 1.000 72.28224  ? 274 LYS   B O   1 
ATOM   4424 C  CB  . LYS   B 1 277 ? -4.86715  10.10596 -11.01154 1.000 74.86364  ? 274 LYS   B CB  1 
ATOM   4425 C  CG  . LYS   B 1 277 ? -4.86648  8.64906  -10.56708 1.000 75.03700  ? 274 LYS   B CG  1 
ATOM   4426 C  CD  . LYS   B 1 277 ? -6.29401  8.15239  -10.36321 1.000 78.58789  ? 274 LYS   B CD  1 
ATOM   4427 C  CE  . LYS   B 1 277 ? -6.34444  6.75303  -9.76977  1.000 77.08282  ? 274 LYS   B CE  1 
ATOM   4428 N  NZ  . LYS   B 1 277 ? -5.97003  5.70540  -10.75723 1.000 85.17094  ? 274 LYS   B NZ  1 
ATOM   4429 N  N   . HIS   B 1 278 ? -3.73836  11.77993 -13.48860 1.000 70.00096  ? 275 HIS   B N   1 
ATOM   4430 C  CA  . HIS   B 1 278 ? -3.81640  12.89947 -14.41454 1.000 65.92963  ? 275 HIS   B CA  1 
ATOM   4431 C  C   . HIS   B 1 278 ? -5.20941  12.96346 -15.02291 1.000 62.53710  ? 275 HIS   B C   1 
ATOM   4432 O  O   . HIS   B 1 278 ? -5.70160  11.96878 -15.56711 1.000 56.22851  ? 275 HIS   B O   1 
ATOM   4433 C  CB  . HIS   B 1 278 ? -2.76148  12.78068 -15.51559 1.000 66.20870  ? 275 HIS   B CB  1 
ATOM   4434 C  CG  . HIS   B 1 278 ? -2.71493  13.96516 -16.42923 1.000 69.45147  ? 275 HIS   B CG  1 
ATOM   4435 N  ND1 . HIS   B 1 278 ? -2.11134  15.15264 -16.07411 1.000 73.12731  ? 275 HIS   B ND1 1 
ATOM   4436 C  CD2 . HIS   B 1 278 ? -3.21284  14.15422 -17.67354 1.000 59.08741  ? 275 HIS   B CD2 1 
ATOM   4437 C  CE1 . HIS   B 1 278 ? -2.22915  16.01868 -17.06455 1.000 62.36369  ? 275 HIS   B CE1 1 
ATOM   4438 N  NE2 . HIS   B 1 278 ? -2.89588  15.43849 -18.04561 1.000 61.73595  ? 275 HIS   B NE2 1 
ATOM   4439 N  N   . ILE   B 1 279 ? -5.84228  14.12818 -14.91594 1.000 54.87266  ? 276 ILE   B N   1 
ATOM   4440 C  CA  . ILE   B 1 279 ? -7.14903  14.38331 -15.50796 1.000 63.30292  ? 276 ILE   B CA  1 
ATOM   4441 C  C   . ILE   B 1 279 ? -6.96461  15.39489 -16.62823 1.000 69.38076  ? 276 ILE   B C   1 
ATOM   4442 O  O   . ILE   B 1 279 ? -6.37203  16.46025 -16.41912 1.000 66.48752  ? 276 ILE   B O   1 
ATOM   4443 C  CB  . ILE   B 1 279 ? -8.16086  14.89824 -14.46921 1.000 70.19119  ? 276 ILE   B CB  1 
ATOM   4444 C  CG1 . ILE   B 1 279 ? -8.17056  14.00015 -13.22982 1.000 67.97996  ? 276 ILE   B CG1 1 
ATOM   4445 C  CG2 . ILE   B 1 279 ? -9.55130  14.99140 -15.08808 1.000 64.25230  ? 276 ILE   B CG2 1 
ATOM   4446 C  CD1 . ILE   B 1 279 ? -8.64566  12.59408 -13.49764 1.000 64.14849  ? 276 ILE   B CD1 1 
ATOM   4447 N  N   . THR   B 1 280 ? -7.46947  15.06447 -17.81283 1.000 65.64628  ? 277 THR   B N   1 
ATOM   4448 C  CA  . THR   B 1 280 ? -7.37801  15.94919 -18.96188 1.000 64.46429  ? 277 THR   B CA  1 
ATOM   4449 C  C   . THR   B 1 280 ? -8.76304  16.13763 -19.56320 1.000 62.77238  ? 277 THR   B C   1 
ATOM   4450 O  O   . THR   B 1 280 ? -9.60580  15.23681 -19.52168 1.000 64.11118  ? 277 THR   B O   1 
ATOM   4451 C  CB  . THR   B 1 280 ? -6.39929  15.40600 -20.01737 1.000 58.53234  ? 277 THR   B CB  1 
ATOM   4452 O  OG1 . THR   B 1 280 ? -6.29169  16.34106 -21.09607 1.000 57.03550  ? 277 THR   B OG1 1 
ATOM   4453 C  CG2 . THR   B 1 280 ? -6.86654  14.06070 -20.55399 1.000 57.41714  ? 277 THR   B CG2 1 
ATOM   4454 N  N   . SER   B 1 281 ? -8.99001  17.32193 -20.12103 1.000 56.78552  ? 278 SER   B N   1 
ATOM   4455 C  CA  . SER   B 1 281 ? -10.29067 17.71179 -20.65812 1.000 54.99040  ? 278 SER   B CA  1 
ATOM   4456 C  C   . SER   B 1 281 ? -10.20132 17.70459 -22.17988 1.000 59.75044  ? 278 SER   B C   1 
ATOM   4457 O  O   . SER   B 1 281 ? -9.69938  18.65460 -22.78507 1.000 64.82090  ? 278 SER   B O   1 
ATOM   4458 C  CB  . SER   B 1 281 ? -10.70470 19.08139 -20.12569 1.000 54.41996  ? 278 SER   B CB  1 
ATOM   4459 O  OG  . SER   B 1 281 ? -11.98549 19.45495 -20.60262 1.000 63.74852  ? 278 SER   B OG  1 
ATOM   4460 N  N   . LYS   B 1 282 ? -10.67966 16.62974 -22.79127 1.000 66.64637  ? 279 LYS   B N   1 
ATOM   4461 C  CA  . LYS   B 1 282 ? -10.73933 16.49833 -24.24127 1.000 62.57026  ? 279 LYS   B CA  1 
ATOM   4462 C  C   . LYS   B 1 282 ? -12.19670 16.68434 -24.67960 1.000 64.25066  ? 279 LYS   B C   1 
ATOM   4463 O  O   . LYS   B 1 282 ? -12.81891 17.65489 -24.23048 1.000 59.10656  ? 279 LYS   B O   1 
ATOM   4464 C  CB  . LYS   B 1 282 ? -10.11052 15.16571 -24.65829 1.000 54.99274  ? 279 LYS   B CB  1 
ATOM   4465 C  CG  . LYS   B 1 282 ? -8.74660  14.87242 -24.05085 1.000 57.69955  ? 279 LYS   B CG  1 
ATOM   4466 C  CD  . LYS   B 1 282 ? -7.68472  15.84488 -24.52885 1.000 54.55595  ? 279 LYS   B CD  1 
ATOM   4467 C  CE  . LYS   B 1 282 ? -6.29346  15.26831 -24.31451 1.000 53.21019  ? 279 LYS   B CE  1 
ATOM   4468 N  NZ  . LYS   B 1 282 ? -6.09282  14.00038 -25.07201 1.000 69.77957  ? 279 LYS   B NZ  1 
ATOM   4469 N  N   . GLU   B 1 283 ? -12.76721 15.81473 -25.51970 1.000 62.84853  ? 280 GLU   B N   1 
ATOM   4470 C  CA  . GLU   B 1 283 ? -14.20430 15.86084 -25.76809 1.000 66.60975  ? 280 GLU   B CA  1 
ATOM   4471 C  C   . GLU   B 1 283 ? -14.98815 15.52610 -24.50620 1.000 72.11774  ? 280 GLU   B C   1 
ATOM   4472 O  O   . GLU   B 1 283 ? -16.10132 16.02664 -24.31720 1.000 77.07471  ? 280 GLU   B O   1 
ATOM   4473 C  CB  . GLU   B 1 283 ? -14.57105 14.90164 -26.90609 1.000 57.85026  ? 280 GLU   B CB  1 
ATOM   4474 C  CG  . GLU   B 1 283 ? -14.60137 13.42977 -26.51280 1.000 51.85950  ? 280 GLU   B CG  1 
ATOM   4475 C  CD  . GLU   B 1 283 ? -13.22619 12.78797 -26.52859 1.000 66.63569  ? 280 GLU   B CD  1 
ATOM   4476 O  OE1 . GLU   B 1 283 ? -12.21809 13.52658 -26.52861 1.000 69.37872  ? 280 GLU   B OE1 1 
ATOM   4477 O  OE2 . GLU   B 1 283 ? -13.15346 11.54120 -26.54676 1.000 70.89421  ? 280 GLU   B OE2 1 
ATOM   4478 N  N   . THR   B 1 284 ? -14.42109 14.68849 -23.63975 1.000 68.85156  ? 281 THR   B N   1 
ATOM   4479 C  CA  . THR   B 1 284 ? -14.95436 14.41683 -22.31341 1.000 69.06886  ? 281 THR   B CA  1 
ATOM   4480 C  C   . THR   B 1 284 ? -13.79878 14.45051 -21.31842 1.000 72.65089  ? 281 THR   B C   1 
ATOM   4481 O  O   . THR   B 1 284 ? -12.67276 14.78591 -21.69887 1.000 68.89228  ? 281 THR   B O   1 
ATOM   4482 C  CB  . THR   B 1 284 ? -15.67979 13.07315 -22.28094 1.000 61.06587  ? 281 THR   B CB  1 
ATOM   4483 O  OG1 . THR   B 1 284 ? -16.29213 12.89903 -20.99519 1.000 73.45845  ? 281 THR   B OG1 1 
ATOM   4484 C  CG2 . THR   B 1 284 ? -14.69900 11.93236 -22.53871 1.000 58.68088  ? 281 THR   B CG2 1 
ATOM   4485 N  N   . LEU   B 1 285 ? -14.04365 14.10668 -20.05479 1.000 70.09188  ? 282 LEU   B N   1 
ATOM   4486 C  CA  . LEU   B 1 285 ? -12.98605 14.07822 -19.05305 1.000 56.45672  ? 282 LEU   B CA  1 
ATOM   4487 C  C   . LEU   B 1 285 ? -12.31904 12.70611 -19.06210 1.000 62.81856  ? 282 LEU   B C   1 
ATOM   4488 O  O   . LEU   B 1 285 ? -12.99866 11.67594 -18.99860 1.000 67.75411  ? 282 LEU   B O   1 
ATOM   4489 C  CB  . LEU   B 1 285 ? -13.54417 14.39634 -17.66445 1.000 61.85355  ? 282 LEU   B CB  1 
ATOM   4490 C  CG  . LEU   B 1 285 ? -14.20284 15.77359 -17.56015 1.000 68.45402  ? 282 LEU   B CG  1 
ATOM   4491 C  CD1 . LEU   B 1 285 ? -14.71573 16.01930 -16.16039 1.000 77.70687  ? 282 LEU   B CD1 1 
ATOM   4492 C  CD2 . LEU   B 1 285 ? -13.23335 16.86472 -17.96726 1.000 67.08978  ? 282 LEU   B CD2 1 
ATOM   4493 N  N   . TYR   B 1 286 ? -10.99083 12.69432 -19.16321 1.000 61.37748  ? 283 TYR   B N   1 
ATOM   4494 C  CA  . TYR   B 1 286 ? -10.21155 11.46445 -19.17591 1.000 62.52882  ? 283 TYR   B CA  1 
ATOM   4495 C  C   . TYR   B 1 286 ? -9.30330  11.41682 -17.95839 1.000 63.06003  ? 283 TYR   B C   1 
ATOM   4496 O  O   . TYR   B 1 286 ? -8.75660  12.44176 -17.54013 1.000 64.90302  ? 283 TYR   B O   1 
ATOM   4497 C  CB  . TYR   B 1 286 ? -9.36661  11.34134 -20.44852 1.000 60.23722  ? 283 TYR   B CB  1 
ATOM   4498 C  CG  . TYR   B 1 286 ? -10.15225 10.94313 -21.67288 1.000 68.26180  ? 283 TYR   B CG  1 
ATOM   4499 C  CD1 . TYR   B 1 286 ? -10.37884 9.60567  -21.96489 1.000 67.73404  ? 283 TYR   B CD1 1 
ATOM   4500 C  CD2 . TYR   B 1 286 ? -10.66839 11.90079 -22.53744 1.000 65.40754  ? 283 TYR   B CD2 1 
ATOM   4501 C  CE1 . TYR   B 1 286 ? -11.09611 9.23033  -23.07979 1.000 64.59556  ? 283 TYR   B CE1 1 
ATOM   4502 C  CE2 . TYR   B 1 286 ? -11.38864 11.53399 -23.65985 1.000 60.20453  ? 283 TYR   B CE2 1 
ATOM   4503 C  CZ  . TYR   B 1 286 ? -11.60053 10.19445 -23.92321 1.000 63.16334  ? 283 TYR   B CZ  1 
ATOM   4504 O  OH  . TYR   B 1 286 ? -12.31567 9.80512  -25.03295 1.000 67.12350  ? 283 TYR   B OH  1 
ATOM   4505 N  N   . CYS   B 1 287 ? -9.14492  10.21909 -17.39905 1.000 64.29090  ? 284 CYS   B N   1 
ATOM   4506 C  CA  . CYS   B 1 287 ? -8.26989  9.97629  -16.25941 1.000 66.45141  ? 284 CYS   B CA  1 
ATOM   4507 C  C   . CYS   B 1 287 ? -7.17665  9.01173  -16.69180 1.000 64.49959  ? 284 CYS   B C   1 
ATOM   4508 O  O   . CYS   B 1 287 ? -7.46404  7.86746  -17.06296 1.000 67.30985  ? 284 CYS   B O   1 
ATOM   4509 C  CB  . CYS   B 1 287 ? -9.05197  9.40587  -15.07536 1.000 71.43913  ? 284 CYS   B CB  1 
ATOM   4510 S  SG  . CYS   B 1 287 ? -8.02812  9.00197  -13.64275 1.000 87.66332  ? 284 CYS   B SG  1 
ATOM   4511 N  N   . ILE   B 1 288 ? -5.93072  9.47244  -16.64990 1.000 62.64763  ? 285 ILE   B N   1 
ATOM   4512 C  CA  . ILE   B 1 288 ? -4.78245  8.67207  -17.05478 1.000 68.79448  ? 285 ILE   B CA  1 
ATOM   4513 C  C   . ILE   B 1 288 ? -3.97899  8.33581  -15.80942 1.000 75.68131  ? 285 ILE   B C   1 
ATOM   4514 O  O   . ILE   B 1 288 ? -3.49445  9.23450  -15.10981 1.000 73.91392  ? 285 ILE   B O   1 
ATOM   4515 C  CB  . ILE   B 1 288 ? -3.91396  9.39611  -18.09296 1.000 64.41077  ? 285 ILE   B CB  1 
ATOM   4516 C  CG1 . ILE   B 1 288 ? -4.76011  9.80536  -19.30196 1.000 66.27210  ? 285 ILE   B CG1 1 
ATOM   4517 C  CG2 . ILE   B 1 288 ? -2.76691  8.49776  -18.51914 1.000 60.73571  ? 285 ILE   B CG2 1 
ATOM   4518 C  CD1 . ILE   B 1 288 ? -3.98745  10.53121 -20.38294 1.000 65.96907  ? 285 ILE   B CD1 1 
ATOM   4519 N  N   . ASP   B 1 289 ? -3.84132  7.04244  -15.53492 1.000 75.35192  ? 286 ASP   B N   1 
ATOM   4520 C  CA  . ASP   B 1 289 ? -3.06202  6.52881  -14.41179 1.000 75.21523  ? 286 ASP   B CA  1 
ATOM   4521 C  C   . ASP   B 1 289 ? -1.98064  5.63834  -15.00433 1.000 70.96316  ? 286 ASP   B C   1 
ATOM   4522 O  O   . ASP   B 1 289 ? -2.14396  4.42077  -15.10390 1.000 72.64745  ? 286 ASP   B O   1 
ATOM   4523 C  CB  . ASP   B 1 289 ? -3.96900  5.76946  -13.41739 1.000 87.90531  ? 286 ASP   B CB  1 
ATOM   4524 C  CG  . ASP   B 1 289 ? -3.21701  5.26482  -12.20219 1.000 90.62931  ? 286 ASP   B CG  1 
ATOM   4525 O  OD1 . ASP   B 1 289 ? -2.41557  4.31657  -12.34119 1.000 98.37921  ? 286 ASP   B OD1 1 
ATOM   4526 O  OD2 . ASP   B 1 289 ? -3.42592  5.82161  -11.10480 1.000 93.99825  ? 286 ASP   B OD2 1 
ATOM   4527 N  N   . GLY   B 1 290 ? -0.87337  6.25640  -15.40782 1.000 61.95181  ? 287 GLY   B N   1 
ATOM   4528 C  CA  . GLY   B 1 290 ? 0.17419   5.52551  -16.08970 1.000 59.46513  ? 287 GLY   B CA  1 
ATOM   4529 C  C   . GLY   B 1 290 ? -0.30905  4.95080  -17.40388 1.000 68.38016  ? 287 GLY   B C   1 
ATOM   4530 O  O   . GLY   B 1 290 ? -0.60469  5.69377  -18.34493 1.000 71.06058  ? 287 GLY   B O   1 
ATOM   4531 N  N   . ALA   B 1 291 ? -0.41003  3.62660  -17.47402 1.000 70.53117  ? 288 ALA   B N   1 
ATOM   4532 C  CA  . ALA   B 1 291 ? -0.88091  2.94002  -18.66858 1.000 66.45430  ? 288 ALA   B CA  1 
ATOM   4533 C  C   . ALA   B 1 291 ? -2.39024  2.72037  -18.67502 1.000 75.30379  ? 288 ALA   B C   1 
ATOM   4534 O  O   . ALA   B 1 291 ? -2.91137  2.13873  -19.63249 1.000 81.35303  ? 288 ALA   B O   1 
ATOM   4535 C  CB  . ALA   B 1 291 ? -0.15873  1.59575  -18.81631 1.000 50.82076  ? 288 ALA   B CB  1 
ATOM   4536 N  N   . LEU   B 1 292 ? -3.09926  3.17703  -17.64425 1.000 72.98035  ? 289 LEU   B N   1 
ATOM   4537 C  CA  . LEU   B 1 292 ? -4.53109  2.94871  -17.49413 1.000 76.19486  ? 289 LEU   B CA  1 
ATOM   4538 C  C   . LEU   B 1 292 ? -5.31722  4.20437  -17.85506 1.000 77.17974  ? 289 LEU   B C   1 
ATOM   4539 O  O   . LEU   B 1 292 ? -4.90505  5.32334  -17.53166 1.000 70.43606  ? 289 LEU   B O   1 
ATOM   4540 C  CB  . LEU   B 1 292 ? -4.86084  2.51893  -16.06269 1.000 81.01163  ? 289 LEU   B CB  1 
ATOM   4541 C  CG  . LEU   B 1 292 ? -3.98770  1.39388  -15.49938 1.000 79.27985  ? 289 LEU   B CG  1 
ATOM   4542 C  CD1 . LEU   B 1 292 ? -4.26855  1.18500  -14.01874 1.000 75.18574  ? 289 LEU   B CD1 1 
ATOM   4543 C  CD2 . LEU   B 1 292 ? -4.18358  0.09923  -16.28347 1.000 70.13899  ? 289 LEU   B CD2 1 
ATOM   4544 N  N   . LEU   B 1 293 ? -6.46280  4.00916  -18.51284 1.000 74.41930  ? 290 LEU   B N   1 
ATOM   4545 C  CA  . LEU   B 1 293 ? -7.28917  5.10484  -19.00199 1.000 66.78640  ? 290 LEU   B CA  1 
ATOM   4546 C  C   . LEU   B 1 293 ? -8.73555  4.92212  -18.56071 1.000 64.48346  ? 290 LEU   B C   1 
ATOM   4547 O  O   . LEU   B 1 293 ? -9.27343  3.81119  -18.60174 1.000 65.79060  ? 290 LEU   B O   1 
ATOM   4548 C  CB  . LEU   B 1 293 ? -7.22067  5.20298  -20.53123 1.000 67.07740  ? 290 LEU   B CB  1 
ATOM   4549 C  CG  . LEU   B 1 293 ? -8.05576  6.31131  -21.17489 1.000 64.63063  ? 290 LEU   B CG  1 
ATOM   4550 C  CD1 . LEU   B 1 293 ? -7.69217  7.67267  -20.59646 1.000 69.30875  ? 290 LEU   B CD1 1 
ATOM   4551 C  CD2 . LEU   B 1 293 ? -7.87529  6.30323  -22.67816 1.000 52.92058  ? 290 LEU   B CD2 1 
ATOM   4552 N  N   . THR   B 1 294 ? -9.35789  6.02224  -18.13552 1.000 61.61848  ? 291 THR   B N   1 
ATOM   4553 C  CA  . THR   B 1 294 ? -10.75138 6.03712  -17.71210 1.000 68.93077  ? 291 THR   B CA  1 
ATOM   4554 C  C   . THR   B 1 294 ? -11.40134 7.33266  -18.17903 1.000 73.64197  ? 291 THR   B C   1 
ATOM   4555 O  O   . THR   B 1 294 ? -10.76009 8.38683  -18.18330 1.000 74.81616  ? 291 THR   B O   1 
ATOM   4556 C  CB  . THR   B 1 294 ? -10.85558 5.89615  -16.18338 1.000 69.38936  ? 291 THR   B CB  1 
ATOM   4557 O  OG1 . THR   B 1 294 ? -10.39187 4.59713  -15.79936 1.000 72.21041  ? 291 THR   B OG1 1 
ATOM   4558 C  CG2 . THR   B 1 294 ? -12.28915 6.07999  -15.69619 1.000 72.57000  ? 291 THR   B CG2 1 
ATOM   4559 N  N   . LYS   B 1 295 ? -12.67128 7.25035  -18.57595 1.000 70.46267  ? 292 LYS   B N   1 
ATOM   4560 C  CA  . LYS   B 1 295 ? -13.42401 8.39839  -19.06159 1.000 70.02412  ? 292 LYS   B CA  1 
ATOM   4561 C  C   . LYS   B 1 295 ? -14.69824 8.58318  -18.24464 1.000 73.77567  ? 292 LYS   B C   1 
ATOM   4562 O  O   . LYS   B 1 295 ? -15.27396 7.61562  -17.73734 1.000 76.89275  ? 292 LYS   B O   1 
ATOM   4563 C  CB  . LYS   B 1 295 ? -13.76205 8.23620  -20.54868 1.000 69.20359  ? 292 LYS   B CB  1 
ATOM   4564 C  CG  . LYS   B 1 295 ? -14.48247 6.93795  -20.87736 1.000 78.92852  ? 292 LYS   B CG  1 
ATOM   4565 C  CD  . LYS   B 1 295 ? -14.53037 6.68246  -22.37835 1.000 72.05325  ? 292 LYS   B CD  1 
ATOM   4566 C  CE  . LYS   B 1 295 ? -15.24865 7.79813  -23.12239 1.000 73.16926  ? 292 LYS   B CE  1 
ATOM   4567 N  NZ  . LYS   B 1 295 ? -15.31330 7.53101  -24.58820 1.000 73.89552  ? 292 LYS   B NZ  1 
ATOM   4568 N  N   . SER   B 1 296 ? -15.13401 9.83821  -18.12360 1.000 65.36480  ? 293 SER   B N   1 
ATOM   4569 C  CA  . SER   B 1 296 ? -16.34660 10.17379 -17.38569 1.000 73.24767  ? 293 SER   B CA  1 
ATOM   4570 C  C   . SER   B 1 296 ? -16.80359 11.57528 -17.77444 1.000 76.09868  ? 293 SER   B C   1 
ATOM   4571 O  O   . SER   B 1 296 ? -15.99559 12.41194 -18.18413 1.000 75.35292  ? 293 SER   B O   1 
ATOM   4572 C  CB  . SER   B 1 296 ? -16.13044 10.08358 -15.86931 1.000 77.95854  ? 293 SER   B CB  1 
ATOM   4573 O  OG  . SER   B 1 296 ? -15.18599 11.04079 -15.42146 1.000 81.16407  ? 293 SER   B OG  1 
ATOM   4574 N  N   . SER   B 1 297 ? -18.11125 11.82256 -17.63038 1.000 78.71516  ? 294 SER   B N   1 
ATOM   4575 C  CA  . SER   B 1 297 ? -18.68299 13.11118 -18.01653 1.000 73.49371  ? 294 SER   B CA  1 
ATOM   4576 C  C   . SER   B 1 297 ? -18.43823 14.18034 -16.95591 1.000 81.81714  ? 294 SER   B C   1 
ATOM   4577 O  O   . SER   B 1 297 ? -18.20015 15.34711 -17.29059 1.000 78.95457  ? 294 SER   B O   1 
ATOM   4578 C  CB  . SER   B 1 297 ? -20.18104 12.96080 -18.27492 1.000 77.96523  ? 294 SER   B CB  1 
ATOM   4579 O  OG  . SER   B 1 297 ? -20.45070 11.75318 -18.96814 1.000 86.83583  ? 294 SER   B OG  1 
ATOM   4580 N  N   . GLU   B 1 298 ? -18.49210 13.80218 -15.68111 1.000 90.83080  ? 295 GLU   B N   1 
ATOM   4581 C  CA  . GLU   B 1 298 ? -18.17006 14.66594 -14.55353 1.000 90.33691  ? 295 GLU   B CA  1 
ATOM   4582 C  C   . GLU   B 1 298 ? -16.97229 14.09405 -13.81211 1.000 80.27445  ? 295 GLU   B C   1 
ATOM   4583 O  O   . GLU   B 1 298 ? -16.56350 12.94812 -14.02385 1.000 70.73477  ? 295 GLU   B O   1 
ATOM   4584 C  CB  . GLU   B 1 298 ? -19.34312 14.80798 -13.56696 1.000 95.39409  ? 295 GLU   B CB  1 
ATOM   4585 C  CG  . GLU   B 1 298 ? -20.09681 16.13865 -13.57671 1.000 99.31491  ? 295 GLU   B CG  1 
ATOM   4586 C  CD  . GLU   B 1 298 ? -20.95406 16.34094 -14.80835 1.000 107.93837 ? 295 GLU   B CD  1 
ATOM   4587 O  OE1 . GLU   B 1 298 ? -21.34181 15.34137 -15.44790 1.000 112.81877 ? 295 GLU   B OE1 1 
ATOM   4588 O  OE2 . GLU   B 1 298 ? -21.25581 17.51231 -15.12696 1.000 117.34246 ? 295 GLU   B OE2 1 
ATOM   4589 N  N   . TYR   B 1 299 ? -16.40996 14.91403 -12.93019 1.000 82.85016  ? 296 TYR   B N   1 
ATOM   4590 C  CA  . TYR   B 1 299 ? -15.33149 14.46040 -12.06268 1.000 87.02099  ? 296 TYR   B CA  1 
ATOM   4591 C  C   . TYR   B 1 299 ? -15.38878 15.24439 -10.76264 1.000 87.40051  ? 296 TYR   B C   1 
ATOM   4592 O  O   . TYR   B 1 299 ? -15.36206 16.47972 -10.77635 1.000 84.84176  ? 296 TYR   B O   1 
ATOM   4593 C  CB  . TYR   B 1 299 ? -13.96196 14.62323 -12.72363 1.000 82.63733  ? 296 TYR   B CB  1 
ATOM   4594 C  CG  . TYR   B 1 299 ? -12.84098 14.16392 -11.82411 1.000 83.53273  ? 296 TYR   B CG  1 
ATOM   4595 C  CD1 . TYR   B 1 299 ? -12.44646 12.83183 -11.79903 1.000 83.07650  ? 296 TYR   B CD1 1 
ATOM   4596 C  CD2 . TYR   B 1 299 ? -12.19636 15.05574 -10.97654 1.000 82.81168  ? 296 TYR   B CD2 1 
ATOM   4597 C  CE1 . TYR   B 1 299 ? -11.42854 12.40339 -10.96405 1.000 76.35320  ? 296 TYR   B CE1 1 
ATOM   4598 C  CE2 . TYR   B 1 299 ? -11.18408 14.63786 -10.13800 1.000 86.48804  ? 296 TYR   B CE2 1 
ATOM   4599 C  CZ  . TYR   B 1 299 ? -10.80126 13.31237 -10.13587 1.000 88.72673  ? 296 TYR   B CZ  1 
ATOM   4600 O  OH  . TYR   B 1 299 ? -9.78838  12.89966 -9.30072  1.000 95.11933  ? 296 TYR   B OH  1 
ATOM   4601 N  N   . LYS   B 1 300 ? -15.46542 14.52005 -9.64730  1.000 91.41212  ? 297 LYS   B N   1 
ATOM   4602 C  CA  . LYS   B 1 300 ? -15.25985 15.08146 -8.31791  1.000 89.53677  ? 297 LYS   B CA  1 
ATOM   4603 C  C   . LYS   B 1 300 ? -14.21728 14.22521 -7.61810  1.000 83.81201  ? 297 LYS   B C   1 
ATOM   4604 O  O   . LYS   B 1 300 ? -14.38255 13.00520 -7.51484  1.000 80.66715  ? 297 LYS   B O   1 
ATOM   4605 C  CB  . LYS   B 1 300 ? -16.56183 15.12085 -7.51263  1.000 78.22545  ? 297 LYS   B CB  1 
ATOM   4606 N  N   . GLY   B 1 301 ? -13.14556 14.85719 -7.14933  1.000 79.80028  ? 298 GLY   B N   1 
ATOM   4607 C  CA  . GLY   B 1 301 ? -12.06828 14.14156 -6.51048  1.000 78.03937  ? 298 GLY   B CA  1 
ATOM   4608 C  C   . GLY   B 1 301 ? -11.03487 15.06771 -5.90453  1.000 82.88205  ? 298 GLY   B C   1 
ATOM   4609 O  O   . GLY   B 1 301 ? -11.15142 16.29629 -5.96918  1.000 77.09252  ? 298 GLY   B O   1 
ATOM   4610 N  N   . PRO   B 1 302 ? -9.98978  14.48629 -5.30184  1.000 86.79683  ? 299 PRO   B N   1 
ATOM   4611 C  CA  . PRO   B 1 302 ? -8.94602  15.28533 -4.64231  1.000 82.45675  ? 299 PRO   B CA  1 
ATOM   4612 C  C   . PRO   B 1 302 ? -7.95671  15.84938 -5.65161  1.000 83.00876  ? 299 PRO   B C   1 
ATOM   4613 O  O   . PRO   B 1 302 ? -7.10141  15.12963 -6.17579  1.000 83.43398  ? 299 PRO   B O   1 
ATOM   4614 C  CB  . PRO   B 1 302 ? -8.28507  14.27208 -3.69703  1.000 81.04119  ? 299 PRO   B CB  1 
ATOM   4615 C  CG  . PRO   B 1 302 ? -8.47098  12.95032 -4.38568  1.000 78.62594  ? 299 PRO   B CG  1 
ATOM   4616 C  CD  . PRO   B 1 302 ? -9.78277  13.03674 -5.12548  1.000 77.67295  ? 299 PRO   B CD  1 
ATOM   4617 N  N   . ILE   B 1 303 ? -8.06193  17.14729 -5.91842  1.000 76.66879  ? 300 ILE   B N   1 
ATOM   4618 C  CA  . ILE   B 1 303 ? -7.24969  17.80865 -6.93307  1.000 86.13045  ? 300 ILE   B CA  1 
ATOM   4619 C  C   . ILE   B 1 303 ? -6.29815  18.77802 -6.24658  1.000 82.45953  ? 300 ILE   B C   1 
ATOM   4620 O  O   . ILE   B 1 303 ? -6.67821  19.46631 -5.29221  1.000 82.66517  ? 300 ILE   B O   1 
ATOM   4621 C  CB  . ILE   B 1 303 ? -8.13081  18.52644 -7.97562  1.000 85.44230  ? 300 ILE   B CB  1 
ATOM   4622 C  CG1 . ILE   B 1 303 ? -9.05196  17.51726 -8.66086  1.000 75.84396  ? 300 ILE   B CG1 1 
ATOM   4623 C  CG2 . ILE   B 1 303 ? -7.27748  19.22789 -9.01618  1.000 76.15415  ? 300 ILE   B CG2 1 
ATOM   4624 C  CD1 . ILE   B 1 303 ? -8.30146  16.38590 -9.33246  1.000 73.30231  ? 300 ILE   B CD1 1 
ATOM   4625 N  N   . THR   B 1 304 ? -5.05437  18.82046 -6.72696  1.000 84.75301  ? 301 THR   B N   1 
ATOM   4626 C  CA  . THR   B 1 304 ? -4.02759  19.69031 -6.16840  1.000 86.22791  ? 301 THR   B CA  1 
ATOM   4627 C  C   . THR   B 1 304 ? -3.42747  20.67071 -7.16661  1.000 82.92686  ? 301 THR   B C   1 
ATOM   4628 O  O   . THR   B 1 304 ? -2.97557  21.73965 -6.75076  1.000 80.18447  ? 301 THR   B O   1 
ATOM   4629 C  CB  . THR   B 1 304 ? -2.89324  18.85239 -5.54558  1.000 81.96199  ? 301 THR   B CB  1 
ATOM   4630 O  OG1 . THR   B 1 304 ? -1.82783  19.71661 -5.12850  1.000 81.79555  ? 301 THR   B OG1 1 
ATOM   4631 C  CG2 . THR   B 1 304 ? -2.36213  17.82271 -6.53809  1.000 80.46887  ? 301 THR   B CG2 1 
ATOM   4632 N  N   . ASP   B 1 305 ? -3.40688  20.34225 -8.45996  1.000 85.57289  ? 302 ASP   B N   1 
ATOM   4633 C  CA  . ASP   B 1 305 ? -2.94287  21.24755 -9.50503  1.000 83.07975  ? 302 ASP   B CA  1 
ATOM   4634 C  C   . ASP   B 1 305 ? -3.96107  21.27241 -10.63444 1.000 75.39449  ? 302 ASP   B C   1 
ATOM   4635 O  O   . ASP   B 1 305 ? -4.51616  20.23167 -10.99527 1.000 73.33904  ? 302 ASP   B O   1 
ATOM   4636 C  CB  . ASP   B 1 305 ? -1.57626  20.82299 -10.07130 1.000 78.17401  ? 302 ASP   B CB  1 
ATOM   4637 C  CG  . ASP   B 1 305 ? -0.58486  20.43271 -8.99257  1.000 90.70782  ? 302 ASP   B CG  1 
ATOM   4638 O  OD1 . ASP   B 1 305 ? -0.41183  21.20431 -8.02493  1.000 103.35785 ? 302 ASP   B OD1 1 
ATOM   4639 O  OD2 . ASP   B 1 305 ? 0.02740   19.34995 -9.11980  1.000 87.03744  ? 302 ASP   B OD2 1 
ATOM   4640 N  N   . VAL   B 1 306 ? -4.20179  22.45925 -11.19287 1.000 69.52185  ? 303 VAL   B N   1 
ATOM   4641 C  CA  . VAL   B 1 306 ? -5.05105  22.62011 -12.37096 1.000 65.28629  ? 303 VAL   B CA  1 
ATOM   4642 C  C   . VAL   B 1 306 ? -4.37605  23.59680 -13.32136 1.000 69.91540  ? 303 VAL   B C   1 
ATOM   4643 O  O   . VAL   B 1 306 ? -3.94925  24.67822 -12.90467 1.000 66.49509  ? 303 VAL   B O   1 
ATOM   4644 C  CB  . VAL   B 1 306 ? -6.46400  23.12429 -12.01836 1.000 78.57471  ? 303 VAL   B CB  1 
ATOM   4645 C  CG1 . VAL   B 1 306 ? -7.31814  23.19668 -13.27116 1.000 63.31064  ? 303 VAL   B CG1 1 
ATOM   4646 C  CG2 . VAL   B 1 306 ? -7.11804  22.23176 -10.97847 1.000 81.83281  ? 303 VAL   B CG2 1 
ATOM   4647 N  N   . PHE   B 1 307 ? -4.30162  23.22854 -14.59847 1.000 72.77427  ? 304 PHE   B N   1 
ATOM   4648 C  CA  . PHE   B 1 307 ? -3.65849  24.03723 -15.62664 1.000 63.63638  ? 304 PHE   B CA  1 
ATOM   4649 C  C   . PHE   B 1 307 ? -4.71421  24.64440 -16.54080 1.000 61.94489  ? 304 PHE   B C   1 
ATOM   4650 O  O   . PHE   B 1 307 ? -5.63155  23.94547 -16.98397 1.000 61.19219  ? 304 PHE   B O   1 
ATOM   4651 C  CB  . PHE   B 1 307 ? -2.67640  23.19310 -16.44276 1.000 63.91634  ? 304 PHE   B CB  1 
ATOM   4652 C  CG  . PHE   B 1 307 ? -1.51950  22.66910 -15.64169 1.000 64.23834  ? 304 PHE   B CG  1 
ATOM   4653 C  CD1 . PHE   B 1 307 ? -1.65620  21.52796 -14.86799 1.000 63.55069  ? 304 PHE   B CD1 1 
ATOM   4654 C  CD2 . PHE   B 1 307 ? -0.29670  23.31945 -15.65819 1.000 61.17177  ? 304 PHE   B CD2 1 
ATOM   4655 C  CE1 . PHE   B 1 307 ? -0.59780  21.04561 -14.12487 1.000 63.52367  ? 304 PHE   B CE1 1 
ATOM   4656 C  CE2 . PHE   B 1 307 ? 0.76678   22.84048 -14.91880 1.000 59.16769  ? 304 PHE   B CE2 1 
ATOM   4657 C  CZ  . PHE   B 1 307 ? 0.61477   21.70360 -14.14955 1.000 60.15523  ? 304 PHE   B CZ  1 
ATOM   4658 N  N   . TYR   B 1 308 ? -4.58250  25.94072 -16.82037 1.000 63.86310  ? 305 TYR   B N   1 
ATOM   4659 C  CA  . TYR   B 1 308 ? -5.50053  26.66271 -17.69067 1.000 64.53616  ? 305 TYR   B CA  1 
ATOM   4660 C  C   . TYR   B 1 308 ? -4.72814  27.30745 -18.83355 1.000 73.79132  ? 305 TYR   B C   1 
ATOM   4661 O  O   . TYR   B 1 308 ? -3.60649  27.78582 -18.64078 1.000 73.73807  ? 305 TYR   B O   1 
ATOM   4662 C  CB  . TYR   B 1 308 ? -6.26513  27.75073 -16.91978 1.000 68.77592  ? 305 TYR   B CB  1 
ATOM   4663 C  CG  . TYR   B 1 308 ? -7.05228  27.24849 -15.72917 1.000 80.03738  ? 305 TYR   B CG  1 
ATOM   4664 C  CD1 . TYR   B 1 308 ? -8.36251  26.80809 -15.87115 1.000 73.47770  ? 305 TYR   B CD1 1 
ATOM   4665 C  CD2 . TYR   B 1 308 ? -6.48783  27.22368 -14.45878 1.000 80.14120  ? 305 TYR   B CD2 1 
ATOM   4666 C  CE1 . TYR   B 1 308 ? -9.08548  26.34869 -14.78270 1.000 77.34512  ? 305 TYR   B CE1 1 
ATOM   4667 C  CE2 . TYR   B 1 308 ? -7.20506  26.76486 -13.36559 1.000 77.41790  ? 305 TYR   B CE2 1 
ATOM   4668 C  CZ  . TYR   B 1 308 ? -8.50250  26.33236 -13.53238 1.000 81.08512  ? 305 TYR   B CZ  1 
ATOM   4669 O  OH  . TYR   B 1 308 ? -9.21893  25.87479 -12.44897 1.000 81.95881  ? 305 TYR   B OH  1 
ATOM   4670 N  N   . LYS   B 1 309 ? -5.33337  27.32676 -20.01979 1.000 80.36840  ? 306 LYS   B N   1 
ATOM   4671 C  CA  . LYS   B 1 309 ? -4.76305  28.04767 -21.14905 1.000 80.35267  ? 306 LYS   B CA  1 
ATOM   4672 C  C   . LYS   B 1 309 ? -5.15616  29.51878 -21.09052 1.000 84.29938  ? 306 LYS   B C   1 
ATOM   4673 O  O   . LYS   B 1 309 ? -6.24749  29.87480 -20.63744 1.000 94.26321  ? 306 LYS   B O   1 
ATOM   4674 C  CB  . LYS   B 1 309 ? -5.21135  27.43327 -22.47469 1.000 85.94831  ? 306 LYS   B CB  1 
ATOM   4675 C  CG  . LYS   B 1 309 ? -4.38582  26.22489 -22.89404 1.000 93.25401  ? 306 LYS   B CG  1 
ATOM   4676 C  CD  . LYS   B 1 309 ? -4.78978  25.71074 -24.26743 1.000 79.08121  ? 306 LYS   B CD  1 
ATOM   4677 C  CE  . LYS   B 1 309 ? -3.96467  24.49285 -24.66158 1.000 85.88960  ? 306 LYS   B CE  1 
ATOM   4678 N  NZ  . LYS   B 1 309 ? -2.59961  24.51629 -24.05681 1.000 88.44332  ? 306 LYS   B NZ  1 
ATOM   4679 N  N   . GLU   B 1 310 ? -4.25837  30.37606 -21.57085 1.000 93.85341  ? 307 GLU   B N   1 
ATOM   4680 C  CA  . GLU   B 1 310 ? -4.44127  31.81507 -21.45314 1.000 101.04714 ? 307 GLU   B CA  1 
ATOM   4681 C  C   . GLU   B 1 310 ? -3.71761  32.51566 -22.59411 1.000 97.34532  ? 307 GLU   B C   1 
ATOM   4682 O  O   . GLU   B 1 310 ? -2.92787  31.91299 -23.32522 1.000 98.28698  ? 307 GLU   B O   1 
ATOM   4683 C  CB  . GLU   B 1 310 ? -3.94236  32.33290 -20.09492 1.000 94.74283  ? 307 GLU   B CB  1 
ATOM   4684 C  CG  . GLU   B 1 310 ? -5.03602  32.92298 -19.21227 1.000 88.48857  ? 307 GLU   B CG  1 
ATOM   4685 C  CD  . GLU   B 1 310 ? -5.82486  34.01232 -19.91643 1.000 111.33065 ? 307 GLU   B CD  1 
ATOM   4686 O  OE1 . GLU   B 1 310 ? -5.19982  34.85089 -20.59962 1.000 117.99867 ? 307 GLU   B OE1 1 
ATOM   4687 O  OE2 . GLU   B 1 310 ? -7.07031  34.02274 -19.79986 1.000 109.36704 ? 307 GLU   B OE2 1 
ATOM   4688 N  N   . ASN   B 1 311 ? -4.01500  33.80557 -22.74804 1.000 107.50155 ? 308 ASN   B N   1 
ATOM   4689 C  CA  . ASN   B 1 311 ? -3.30806  34.64306 -23.70766 1.000 110.04485 ? 308 ASN   B CA  1 
ATOM   4690 C  C   . ASN   B 1 311 ? -3.04997  36.03889 -23.15237 1.000 118.96143 ? 308 ASN   B C   1 
ATOM   4691 O  O   . ASN   B 1 311 ? -1.90206  36.38486 -22.85443 1.000 112.18823 ? 308 ASN   B O   1 
ATOM   4692 C  CB  . ASN   B 1 311 ? -4.08867  34.74065 -25.01772 1.000 109.64836 ? 308 ASN   B CB  1 
ATOM   4693 C  CG  . ASN   B 1 311 ? -3.45494  35.70913 -25.99511 1.000 122.98031 ? 308 ASN   B CG  1 
ATOM   4694 O  OD1 . ASN   B 1 311 ? -4.04017  36.73849 -26.33343 1.000 129.17699 ? 308 ASN   B OD1 1 
ATOM   4695 N  ND2 . ASN   B 1 311 ? -2.24169  35.39746 -26.43528 1.000 128.08145 ? 308 ASN   B ND2 1 
ATOM   4696 N  N   . SER   B 1 312 ? -4.10644  36.85182 -23.00637 1.000 126.31908 ? 309 SER   B N   1 
ATOM   4697 C  CA  . SER   B 1 312 ? -3.95990  38.21214 -22.48776 1.000 124.64596 ? 309 SER   B CA  1 
ATOM   4698 C  C   . SER   B 1 312 ? -5.19628  38.58980 -21.66275 1.000 125.38433 ? 309 SER   B C   1 
ATOM   4699 O  O   . SER   B 1 312 ? -6.02165  39.42085 -22.04477 1.000 125.64010 ? 309 SER   B O   1 
ATOM   4700 C  CB  . SER   B 1 312 ? -3.72315  39.20898 -23.62575 1.000 123.71423 ? 309 SER   B CB  1 
ATOM   4701 O  OG  . SER   B 1 312 ? -3.51114  40.52062 -23.13280 1.000 128.26788 ? 309 SER   B OG  1 
ATOM   4702 N  N   . TYR   B 1 313 ? -5.31229  37.99607 -20.47619 1.000 126.55186 ? 310 TYR   B N   1 
ATOM   4703 C  CA  . TYR   B 1 313 ? -6.42276  38.31153 -19.58799 1.000 124.77518 ? 310 TYR   B CA  1 
ATOM   4704 C  C   . TYR   B 1 313 ? -6.22088  39.67178 -18.93202 1.000 129.98425 ? 310 TYR   B C   1 
ATOM   4705 O  O   . TYR   B 1 313 ? -5.11960  40.01331 -18.49079 1.000 134.06126 ? 310 TYR   B O   1 
ATOM   4706 C  CB  . TYR   B 1 313 ? -6.57255  37.22773 -18.51592 1.000 120.88835 ? 310 TYR   B CB  1 
ATOM   4707 C  CG  . TYR   B 1 313 ? -7.32074  37.68401 -17.27975 1.000 123.90289 ? 310 TYR   B CG  1 
ATOM   4708 C  CD1 . TYR   B 1 313 ? -8.70893  37.72905 -17.24912 1.000 123.43001 ? 310 TYR   B CD1 1 
ATOM   4709 C  CD2 . TYR   B 1 313 ? -6.62982  38.05574 -16.13169 1.000 132.75080 ? 310 TYR   B CD2 1 
ATOM   4710 C  CE1 . TYR   B 1 313 ? -9.38589  38.14990 -16.11259 1.000 128.98883 ? 310 TYR   B CE1 1 
ATOM   4711 C  CE2 . TYR   B 1 313 ? -7.29500  38.47493 -14.99385 1.000 133.29651 ? 310 TYR   B CE2 1 
ATOM   4712 C  CZ  . TYR   B 1 313 ? -8.67389  38.51899 -14.98862 1.000 128.39793 ? 310 TYR   B CZ  1 
ATOM   4713 O  OH  . TYR   B 1 313 ? -9.33936  38.93371 -13.85523 1.000 125.17927 ? 310 TYR   B OH  1 
ATOM   4714 N  N   . THR   B 1 314 ? -7.29894  40.45200 -18.87254 1.000 132.95311 ? 311 THR   B N   1 
ATOM   4715 C  CA  . THR   B 1 314 ? -7.30855  41.72971 -18.17762 1.000 131.88031 ? 311 THR   B CA  1 
ATOM   4716 C  C   . THR   B 1 314 ? -8.63023  41.87582 -17.43725 1.000 134.35511 ? 311 THR   B C   1 
ATOM   4717 O  O   . THR   B 1 314 ? -9.67748  41.45958 -17.94198 1.000 135.20597 ? 311 THR   B O   1 
ATOM   4718 C  CB  . THR   B 1 314 ? -7.11912  42.89915 -19.15754 1.000 133.99249 ? 311 THR   B CB  1 
ATOM   4719 O  OG1 . THR   B 1 314 ? -5.97517  42.65222 -19.98621 1.000 135.30684 ? 311 THR   B OG1 1 
ATOM   4720 C  CG2 . THR   B 1 314 ? -6.91665  44.20584 -18.40696 1.000 124.86776 ? 311 THR   B CG2 1 
ATOM   4721 N  N   . THR   B 1 315 ? -8.58277  42.46108 -16.24267 1.000 138.57890 ? 312 THR   B N   1 
ATOM   4722 C  CA  . THR   B 1 315 ? -9.78681  42.59779 -15.42753 1.000 135.06808 ? 312 THR   B CA  1 
ATOM   4723 C  C   . THR   B 1 315 ? -10.48153 43.92291 -15.73424 1.000 136.01742 ? 312 THR   B C   1 
ATOM   4724 O  O   . THR   B 1 315 ? -10.05732 44.66599 -16.62069 1.000 134.27927 ? 312 THR   B O   1 
ATOM   4725 C  CB  . THR   B 1 315 ? -9.47900  42.52409 -13.91978 1.000 129.46324 ? 312 THR   B CB  1 
ATOM   4726 O  OG1 . THR   B 1 315 ? -10.70661 42.44054 -13.18483 1.000 128.24760 ? 312 THR   B OG1 1 
ATOM   4727 C  CG2 . THR   B 1 315 ? -8.71874  43.75814 -13.47109 1.000 123.00165 ? 312 THR   B CG2 1 
HETATM 4728 C  C13 . A1A6J C 2 .   ? 3.80135   27.04006 -62.32155 1.000 60.82206  ? 401 A1A6J A C13 1 
HETATM 4729 C  C14 . A1A6J C 2 .   ? 0.65729   27.78206 -57.85469 1.000 57.16015  ? 401 A1A6J A C14 1 
HETATM 4730 C  C15 . A1A6J C 2 .   ? -0.17471  28.00695 -56.76195 1.000 56.10011  ? 401 A1A6J A C15 1 
HETATM 4731 C  C16 . A1A6J C 2 .   ? -0.72485  29.35071 -56.51250 1.000 63.57880  ? 401 A1A6J A C16 1 
HETATM 4732 C  C19 . A1A6J C 2 .   ? -1.82254  31.08881 -55.72943 1.000 68.19385  ? 401 A1A6J A C19 1 
HETATM 4733 C  C20 . A1A6J C 2 .   ? -1.62754  29.75885 -55.51451 1.000 68.68948  ? 401 A1A6J A C20 1 
HETATM 4734 N  N18 . A1A6J C 2 .   ? -1.07350  31.43294 -56.79290 1.000 76.13763  ? 401 A1A6J A N18 1 
HETATM 4735 C  C12 . A1A6J C 2 .   ? 2.76022   25.09748 -59.59435 1.000 61.46769  ? 401 A1A6J A C12 1 
HETATM 4736 C  C2  . A1A6J C 2 .   ? -2.52387  23.94789 -56.24137 1.000 53.62987  ? 401 A1A6J A C2  1 
HETATM 4737 C  C21 . A1A6J C 2 .   ? -0.94653  32.75729 -57.40844 1.000 82.36980  ? 401 A1A6J A C21 1 
HETATM 4738 C  C22 . A1A6J C 2 .   ? -1.11812  33.85273 -56.38323 1.000 85.28702  ? 401 A1A6J A C22 1 
HETATM 4739 C  C23 . A1A6J C 2 .   ? -0.49675  26.95314 -55.91224 1.000 46.85117  ? 401 A1A6J A C23 1 
HETATM 4740 C  C24 . A1A6J C 2 .   ? 0.09480   24.77951 -53.76896 1.000 53.31514  ? 401 A1A6J A C24 1 
HETATM 4741 C  C25 . A1A6J C 2 .   ? -4.01171  23.86641 -56.11069 1.000 48.35786  ? 401 A1A6J A C25 1 
HETATM 4742 C  C26 . A1A6J C 2 .   ? -4.64203  22.62361 -55.95310 1.000 50.73758  ? 401 A1A6J A C26 1 
HETATM 4743 C  C27 . A1A6J C 2 .   ? -6.03122  22.58612 -55.86281 1.000 47.08026  ? 401 A1A6J A C27 1 
HETATM 4744 C  C28 . A1A6J C 2 .   ? -6.77949  23.74946 -55.91970 1.000 51.57770  ? 401 A1A6J A C28 1 
HETATM 4745 C  C29 . A1A6J C 2 .   ? -6.15388  24.96778 -56.07120 1.000 52.01682  ? 401 A1A6J A C29 1 
HETATM 4746 C  C30 . A1A6J C 2 .   ? -4.77429  25.03459 -56.16636 1.000 48.65182  ? 401 A1A6J A C30 1 
HETATM 4747 C  C31 . A1A6J C 2 .   ? -3.87003  21.33144 -55.81033 1.000 47.90390  ? 401 A1A6J A C31 1 
HETATM 4748 C  C32 . A1A6J C 2 .   ? -4.65418  20.12170 -56.29168 1.000 46.71412  ? 401 A1A6J A C32 1 
HETATM 4749 C  C33 . A1A6J C 2 .   ? -3.91484  18.83314 -56.03727 1.000 55.49359  ? 401 A1A6J A C33 1 
HETATM 4750 C  C36 . A1A6J C 2 .   ? -3.93788  16.34565 -53.71072 1.000 60.57849  ? 401 A1A6J A C36 1 
HETATM 4751 C  C37 . A1A6J C 2 .   ? -3.16296  15.09263 -53.37633 1.000 60.95669  ? 401 A1A6J A C37 1 
HETATM 4752 C  C38 . A1A6J C 2 .   ? -3.08577  14.14099 -54.55667 1.000 55.02179  ? 401 A1A6J A C38 1 
HETATM 4753 C  C39 . A1A6J C 2 .   ? -2.80328  12.72335 -54.11619 1.000 66.02459  ? 401 A1A6J A C39 1 
HETATM 4754 C  C4  . A1A6J C 2 .   ? -0.39886  24.55113 -55.19318 1.000 59.52054  ? 401 A1A6J A C4  1 
HETATM 4755 C  C41 . A1A6J C 2 .   ? -1.79875  11.85009 -56.31734 1.000 70.33025  ? 401 A1A6J A C41 1 
HETATM 4756 C  C42 . A1A6J C 2 .   ? -0.63688  10.86826 -56.04262 1.000 71.78091  ? 401 A1A6J A C42 1 
HETATM 4757 C  C43 . A1A6J C 2 .   ? 0.71524   11.39032 -56.52870 1.000 70.92848  ? 401 A1A6J A C43 1 
HETATM 4758 C  C44 . A1A6J C 2 .   ? -0.86494  11.07018 -54.52705 1.000 66.52964  ? 401 A1A6J A C44 1 
HETATM 4759 C  C45 . A1A6J C 2 .   ? -0.89276  9.43680  -56.51546 1.000 75.38116  ? 401 A1A6J A C45 1 
HETATM 4760 C  C5  . A1A6J C 2 .   ? -0.00184  25.67254 -56.13627 1.000 56.71575  ? 401 A1A6J A C5  1 
HETATM 4761 C  C6  . A1A6J C 2 .   ? 0.82807   25.46240 -57.23284 1.000 51.16762  ? 401 A1A6J A C6  1 
HETATM 4762 C  C7  . A1A6J C 2 .   ? 1.15972   26.50619 -58.09275 1.000 59.79654  ? 401 A1A6J A C7  1 
HETATM 4763 C  C8  . A1A6J C 2 .   ? 2.04163   26.25895 -59.25824 1.000 60.84395  ? 401 A1A6J A C8  1 
HETATM 4764 C  C9  . A1A6J C 2 .   ? 2.35575   27.13862 -60.26957 1.000 61.16473  ? 401 A1A6J A C9  1 
HETATM 4765 N  N10 . A1A6J C 2 .   ? 3.19098   26.51104 -61.10965 1.000 71.68158  ? 401 A1A6J A N10 1 
HETATM 4766 N  N11 . A1A6J C 2 .   ? 3.45475   25.24621 -60.71108 1.000 67.58884  ? 401 A1A6J A N11 1 
HETATM 4767 N  N17 . A1A6J C 2 .   ? -0.38553  30.37997 -57.29673 1.000 71.38177  ? 401 A1A6J A N17 1 
HETATM 4768 N  N3  . A1A6J C 2 .   ? -1.85225  24.39595 -55.17403 1.000 58.32528  ? 401 A1A6J A N3  1 
HETATM 4769 N  N34 . A1A6J C 2 .   ? -3.88087  18.45517 -54.75250 1.000 55.71079  ? 401 A1A6J A N34 1 
HETATM 4770 N  N35 . A1A6J C 2 .   ? -3.25514  17.26994 -54.39998 1.000 50.21283  ? 401 A1A6J A N35 1 
HETATM 4771 N  N40 . A1A6J C 2 .   ? -1.95270  11.99390 -54.86586 1.000 67.50509  ? 401 A1A6J A N40 1 
HETATM 4772 O  O1  . A1A6J C 2 .   ? -1.95820  23.59697 -57.27308 1.000 59.32903  ? 401 A1A6J A O1  1 
HETATM 4773 O  O46 . A1A6J C 2 .   ? -3.33958  12.26674 -53.11891 1.000 62.20210  ? 401 A1A6J A O46 1 
HETATM 4774 O  O47 . A1A6J C 2 .   ? -5.11324  16.49512 -53.38552 1.000 62.66651  ? 401 A1A6J A O47 1 
HETATM 4775 O  O48 . A1A6J C 2 .   ? -3.37830  18.19287 -56.93664 1.000 63.05376  ? 401 A1A6J A O48 1 
HETATM 4776 S  S1  . DTT   D 3 .   ? -1.21743  54.63073 -51.44583 1.000 153.48652 ? 402 DTT   A S1  1 
HETATM 4777 C  C1  . DTT   D 3 .   ? -2.27421  55.15406 -52.81825 1.000 148.65565 ? 402 DTT   A C1  1 
HETATM 4778 C  C2  . DTT   D 3 .   ? -2.89096  56.53819 -52.64186 1.000 143.93549 ? 402 DTT   A C2  1 
HETATM 4779 O  O2  . DTT   D 3 .   ? -3.62829  56.57902 -51.43942 1.000 127.81305 ? 402 DTT   A O2  1 
HETATM 4780 C  C3  . DTT   D 3 .   ? -3.80109  56.87472 -53.82233 1.000 144.74086 ? 402 DTT   A C3  1 
HETATM 4781 O  O3  . DTT   D 3 .   ? -4.70418  57.89907 -53.46473 1.000 129.28294 ? 402 DTT   A O3  1 
HETATM 4782 C  C4  . DTT   D 3 .   ? -2.99421  57.31979 -55.03630 1.000 135.84465 ? 402 DTT   A C4  1 
HETATM 4783 S  S4  . DTT   D 3 .   ? -2.73149  59.11014 -55.05069 1.000 132.18997 ? 402 DTT   A S4  1 
HETATM 4784 ZN ZN  . ZN    E 4 .   ? -19.65094 29.70726 -35.29502 1.000 58.32237  ? 403 ZN    A ZN  1 
HETATM 4785 ZN ZN  . ZN    F 4 .   ? -14.66438 4.46042  -49.81718 1.000 120.82122 ? 404 ZN    A ZN  1 
HETATM 4786 ZN ZN  . ZN    G 4 .   ? 19.67056  22.27364 -34.96730 1.000 155.85634 ? 405 ZN    A ZN  1 
HETATM 4787 ZN ZN  . ZN    H 4 .   ? 1.72677   10.76070 -50.70457 1.000 98.33270  ? 406 ZN    A ZN  1 
HETATM 4788 ZN ZN  . ZN    I 4 .   ? 1.97390   55.44498 -54.44554 1.000 184.93887 ? 407 ZN    A ZN  1 
HETATM 4789 CL CL  . CL    J 5 .   ? -18.04044 28.77438 -36.44567 1.000 63.43794  ? 408 CL    A CL  1 
HETATM 4790 CL CL  . CL    K 5 .   ? -21.08335 30.66193 -36.67399 1.000 59.94372  ? 409 CL    A CL  1 
HETATM 4791 CL CL  . CL    L 5 .   ? -11.19825 4.15558  -49.22333 1.000 98.55339  ? 410 CL    A CL  1 
HETATM 4792 CL CL  . CL    M 5 .   ? 8.66873   29.21177 -35.33019 1.000 78.48794  ? 411 CL    A CL  1 
HETATM 4793 CL CL  . CL    N 5 .   ? 19.38030  20.34445 -32.15643 1.000 127.15689 ? 412 CL    A CL  1 
HETATM 4794 C  C13 . A1A6J O 2 .   ? -3.64113  15.53711 5.08774   1.000 101.68459 ? 401 A1A6J B C13 1 
HETATM 4795 C  C14 . A1A6J O 2 .   ? -0.64198  18.47376 1.51001   1.000 94.68539  ? 401 A1A6J B C14 1 
HETATM 4796 C  C15 . A1A6J O 2 .   ? 0.06468   19.26577 0.60983   1.000 84.35707  ? 401 A1A6J B C15 1 
HETATM 4797 C  C16 . A1A6J O 2 .   ? 0.34746   20.67578 0.92767   1.000 93.17543  ? 401 A1A6J B C16 1 
HETATM 4798 C  C19 . A1A6J O 2 .   ? 0.48988   22.65806 1.87034   1.000 115.73221 ? 401 A1A6J B C19 1 
HETATM 4799 C  C20 . A1A6J O 2 .   ? -0.05899  21.42383 2.04628   1.000 115.81119 ? 401 A1A6J B C20 1 
HETATM 4800 N  N18 . A1A6J O 2 .   ? 1.17647   22.62586 0.71363   1.000 111.56443 ? 401 A1A6J B N18 1 
HETATM 4801 C  C12 . A1A6J O 2 .   ? -1.98796  14.93013 2.05638   1.000 95.15670  ? 401 A1A6J B C12 1 
HETATM 4802 C  C2  . A1A6J O 2 .   ? 2.97417   16.11062 -1.41351  1.000 79.68422  ? 401 A1A6J B C2  1 
HETATM 4803 C  C21 . A1A6J O 2 .   ? 1.95825   23.70609 0.10300   1.000 104.96308 ? 401 A1A6J B C21 1 
HETATM 4804 C  C22 . A1A6J O 2 .   ? 1.84650   24.98750 0.89243   1.000 99.63611  ? 401 A1A6J B C22 1 
HETATM 4805 C  C23 . A1A6J O 2 .   ? 0.51998   18.71515 -0.58464  1.000 85.68483  ? 401 A1A6J B C23 1 
HETATM 4806 C  C24 . A1A6J O 2 .   ? 0.24265   17.59512 -3.42062  1.000 87.86820  ? 401 A1A6J B C24 1 
HETATM 4807 C  C25 . A1A6J O 2 .   ? 4.46083   16.23928 -1.52253  1.000 65.58760  ? 401 A1A6J B C25 1 
HETATM 4808 C  C26 . A1A6J O 2 .   ? 5.22894   15.13735 -1.92275  1.000 58.79408  ? 401 A1A6J B C26 1 
HETATM 4809 C  C27 . A1A6J O 2 .   ? 6.61300   15.27745 -1.99357  1.000 58.54530  ? 401 A1A6J B C27 1 
HETATM 4810 C  C28 . A1A6J O 2 .   ? 7.22267   16.47984 -1.67977  1.000 62.82231  ? 401 A1A6J B C28 1 
HETATM 4811 C  C29 . A1A6J O 2 .   ? 6.46153   17.56075 -1.28852  1.000 73.10891  ? 401 A1A6J B C29 1 
HETATM 4812 C  C30 . A1A6J O 2 .   ? 5.08380   17.44898 -1.20816  1.000 68.14140  ? 401 A1A6J B C30 1 
HETATM 4813 C  C31 . A1A6J O 2 .   ? 4.60716   13.81652 -2.31528  1.000 61.02351  ? 401 A1A6J B C31 1 
HETATM 4814 C  C32 . A1A6J O 2 .   ? 5.63485   12.74747 -2.65895  1.000 70.06481  ? 401 A1A6J B C32 1 
HETATM 4815 C  C33 . A1A6J O 2 .   ? 4.98291   11.51445 -3.23215  1.000 86.37030  ? 401 A1A6J B C33 1 
HETATM 4816 C  C36 . A1A6J O 2 .   ? 5.03767   9.69758  -6.06037  1.000 78.36939  ? 401 A1A6J B C36 1 
HETATM 4817 C  C37 . A1A6J O 2 .   ? 4.31128   8.53546  -6.69320  1.000 89.20509  ? 401 A1A6J B C37 1 
HETATM 4818 C  C38 . A1A6J O 2 .   ? 4.29997   7.31220  -5.79614  1.000 77.58258  ? 401 A1A6J B C38 1 
HETATM 4819 C  C39 . A1A6J O 2 .   ? 4.05991   6.04365  -6.58269  1.000 85.96959  ? 401 A1A6J B C39 1 
HETATM 4820 C  C4  . A1A6J O 2 .   ? 0.78288   16.82709 -2.21906  1.000 89.09172  ? 401 A1A6J B C4  1 
HETATM 4821 C  C41 . A1A6J O 2 .   ? 3.18301   4.28995  -4.90698  1.000 100.95520 ? 401 A1A6J B C41 1 
HETATM 4822 C  C42 . A1A6J O 2 .   ? 1.80026   3.76043  -5.35165  1.000 106.54680 ? 401 A1A6J B C42 1 
HETATM 4823 C  C43 . A1A6J O 2 .   ? 0.67050   4.08443  -4.37362  1.000 96.98185  ? 401 A1A6J B C43 1 
HETATM 4824 C  C44 . A1A6J O 2 .   ? 1.85862   4.71349  -6.56697  1.000 100.40839 ? 401 A1A6J B C44 1 
HETATM 4825 C  C45 . A1A6J O 2 .   ? 1.79348   2.28795  -5.76423  1.000 108.24828 ? 401 A1A6J B C45 1 
HETATM 4826 C  C5  . A1A6J O 2 .   ? 0.28059   17.38109 -0.89733  1.000 92.06141  ? 401 A1A6J B C5  1 
HETATM 4827 C  C6  . A1A6J O 2 .   ? -0.42478  16.60108 0.01375   1.000 94.19452  ? 401 A1A6J B C6  1 
HETATM 4828 C  C7  . A1A6J O 2 .   ? -0.88908  17.13749 1.21224   1.000 98.12337  ? 401 A1A6J B C7  1 
HETATM 4829 C  C8  . A1A6J O 2 .   ? -1.66402  16.29458 2.15315   1.000 98.94321  ? 401 A1A6J B C8  1 
HETATM 4830 C  C9  . A1A6J O 2 .   ? -2.25941  16.68552 3.33197   1.000 95.35106  ? 401 A1A6J B C9  1 
HETATM 4831 N  N10 . A1A6J O 2 .   ? -2.87167  15.61385 3.85259   1.000 105.43635 ? 401 A1A6J B N10 1 
HETATM 4832 N  N11 . A1A6J O 2 .   ? -2.71716  14.51389 3.08014   1.000 104.38664 ? 401 A1A6J B N11 1 
HETATM 4833 N  N17 . A1A6J O 2 .   ? 1.10579   21.41495 0.11016   1.000 98.32494  ? 401 A1A6J B N17 1 
HETATM 4834 N  N3  . A1A6J O 2 .   ? 2.24351   16.84719 -2.25769  1.000 85.32157  ? 401 A1A6J B N3  1 
HETATM 4835 N  N34 . A1A6J O 2 .   ? 4.87622   11.51052 -4.56767  1.000 80.65852  ? 401 A1A6J B N34 1 
HETATM 4836 N  N35 . A1A6J O 2 .   ? 4.30393   10.42255 -5.20615  1.000 74.47335  ? 401 A1A6J B N35 1 
HETATM 4837 N  N40 . A1A6J O 2 .   ? 3.17195   5.15925  -6.08888  1.000 98.02223  ? 401 A1A6J B N40 1 
HETATM 4838 O  O1  . A1A6J O 2 .   ? 2.46251   15.34316 -0.60345  1.000 86.59831  ? 401 A1A6J B O1  1 
HETATM 4839 O  O46 . A1A6J O 2 .   ? 4.66037   5.83877  -7.62521  1.000 85.71811  ? 401 A1A6J B O46 1 
HETATM 4840 O  O47 . A1A6J O 2 .   ? 6.21489   9.94809  -6.30551  1.000 79.36042  ? 401 A1A6J B O47 1 
HETATM 4841 O  O48 . A1A6J O 2 .   ? 4.57196   10.59717 -2.52668  1.000 85.53730  ? 401 A1A6J B O48 1 
HETATM 4842 ZN ZN  . ZN    P 4 .   ? 20.12447  28.14466 -19.92672 1.000 62.96432  ? 402 ZN    B ZN  1 
HETATM 4843 ZN ZN  . ZN    Q 4 .   ? 14.90998  0.28714  -12.63277 1.000 118.85490 ? 403 ZN    B ZN  1 
HETATM 4844 ZN ZN  . ZN    R 4 .   ? -19.41130 19.51660 -22.15219 1.000 144.78852 ? 404 ZN    B ZN  1 
HETATM 4845 ZN ZN  . ZN    S 4 .   ? 19.03766  24.02248 -13.03362 1.000 142.52807 ? 405 ZN    B ZN  1 
HETATM 4846 ZN ZN  . ZN    T 4 .   ? -0.00905  4.82721  -10.94308 1.000 112.60933 ? 406 ZN    B ZN  1 
HETATM 4847 CL CL  . CL    U 5 .   ? 21.65875  28.72679 -18.41814 1.000 64.52968  ? 407 CL    B CL  1 
HETATM 4848 CL CL  . CL    V 5 .   ? 18.62574  27.00650 -18.70983 1.000 57.82332  ? 408 CL    B CL  1 
HETATM 4849 CL CL  . CL    W 5 .   ? 17.63386  24.40002 -11.17674 1.000 138.56025 ? 409 CL    B CL  1 
HETATM 4850 CL CL  . CL    X 5 .   ? 21.18708  25.50678 -13.03598 1.000 134.96783 ? 410 CL    B CL  1 
HETATM 4851 O  O   . HOH   Y 6 .   ? 9.08192   44.41968 -38.99759 1.000 87.67450  ? 501 HOH   A O   1 
HETATM 4852 O  O   . HOH   Y 6 .   ? 3.80539   5.12784  -37.91947 1.000 49.45728  ? 502 HOH   A O   1 
HETATM 4853 O  O   . HOH   Y 6 .   ? 1.25331   35.17676 -41.95354 1.000 67.86095  ? 503 HOH   A O   1 
HETATM 4854 O  O   . HOH   Y 6 .   ? -2.25226  3.75234  -48.94774 1.000 60.89385  ? 504 HOH   A O   1 
HETATM 4855 O  O   . HOH   Y 6 .   ? 2.13596   21.84376 -43.64627 1.000 49.62303  ? 505 HOH   A O   1 
HETATM 4856 O  O   . HOH   Y 6 .   ? -17.39280 19.47274 -55.53622 1.000 71.10273  ? 506 HOH   A O   1 
HETATM 4857 O  O   . HOH   Y 6 .   ? -3.97653  51.38174 -38.92751 1.000 84.98118  ? 507 HOH   A O   1 
HETATM 4858 O  O   . HOH   Y 6 .   ? 8.30608   36.61351 -33.94802 1.000 72.61551  ? 508 HOH   A O   1 
HETATM 4859 O  O   . HOH   Y 6 .   ? -1.91975  37.66723 -48.57447 1.000 64.26778  ? 509 HOH   A O   1 
HETATM 4860 O  O   . HOH   Y 6 .   ? -6.29102  3.97725  -37.98546 1.000 58.75105  ? 510 HOH   A O   1 
HETATM 4861 O  O   . HOH   Y 6 .   ? -14.82594 21.06791 -55.48006 1.000 82.30048  ? 511 HOH   A O   1 
HETATM 4862 O  O   . HOH   Y 6 .   ? -11.02994 15.36350 -51.07635 1.000 50.76333  ? 512 HOH   A O   1 
HETATM 4863 O  O   . HOH   Y 6 .   ? 6.77491   31.77182 -55.37883 1.000 55.83671  ? 513 HOH   A O   1 
HETATM 4864 O  O   . HOH   Y 6 .   ? -6.26202  5.27655  -45.24526 1.000 48.10118  ? 514 HOH   A O   1 
HETATM 4865 O  O   . HOH   Y 6 .   ? -11.20196 4.13839  -51.86965 1.000 66.77680  ? 515 HOH   A O   1 
HETATM 4866 O  O   . HOH   Y 6 .   ? -18.86296 17.85845 -48.73502 1.000 50.56152  ? 516 HOH   A O   1 
HETATM 4867 O  O   . HOH   Y 6 .   ? -1.05782  31.78395 -46.12986 1.000 52.82497  ? 517 HOH   A O   1 
HETATM 4868 O  O   . HOH   Y 6 .   ? -12.52322 12.84830 -35.22227 1.000 53.56619  ? 518 HOH   A O   1 
HETATM 4869 O  O   . HOH   Y 6 .   ? -26.46227 20.77368 -30.46779 1.000 54.16733  ? 519 HOH   A O   1 
HETATM 4870 O  O   . HOH   Y 6 .   ? -22.88778 26.24288 -29.89611 1.000 55.32736  ? 520 HOH   A O   1 
HETATM 4871 O  O   . HOH   Y 6 .   ? 15.69797  29.29848 -49.17868 1.000 67.00098  ? 521 HOH   A O   1 
HETATM 4872 O  O   . HOH   Y 6 .   ? -30.38223 15.87001 -32.23402 1.000 66.02903  ? 522 HOH   A O   1 
HETATM 4873 O  O   . HOH   Y 6 .   ? -0.70504  25.31671 -50.18518 1.000 53.61585  ? 523 HOH   A O   1 
HETATM 4874 O  O   . HOH   Y 6 .   ? -10.57336 12.70659 -50.43182 1.000 49.62240  ? 524 HOH   A O   1 
HETATM 4875 O  O   . HOH   Y 6 .   ? 0.37259   3.95207  -35.33202 1.000 52.90470  ? 525 HOH   A O   1 
HETATM 4876 O  O   . HOH   Y 6 .   ? -5.37275  29.90035 -56.33623 1.000 71.49724  ? 526 HOH   A O   1 
HETATM 4877 O  O   . HOH   Y 6 .   ? 7.56318   21.52454 -34.59044 1.000 57.44728  ? 527 HOH   A O   1 
HETATM 4878 O  O   . HOH   Y 6 .   ? -21.27010 13.93680 -34.99650 1.000 63.77068  ? 528 HOH   A O   1 
HETATM 4879 O  O   . HOH   Y 6 .   ? 11.63795  33.53270 -41.37108 1.000 67.69109  ? 529 HOH   A O   1 
HETATM 4880 O  O   . HOH   Y 6 .   ? -18.99611 14.93825 -48.75143 1.000 50.14398  ? 530 HOH   A O   1 
HETATM 4881 O  O   . HOH   Y 6 .   ? 9.90572   33.72632 -49.86716 1.000 67.31271  ? 531 HOH   A O   1 
HETATM 4882 O  O   . HOH   Y 6 .   ? -17.62896 12.62677 -49.64444 1.000 43.64597  ? 532 HOH   A O   1 
HETATM 4883 O  O   . HOH   Y 6 .   ? 1.62288   8.18515  -48.63567 1.000 66.16604  ? 533 HOH   A O   1 
HETATM 4884 O  O   . HOH   Y 6 .   ? -37.73452 16.59020 -32.97432 1.000 68.60165  ? 534 HOH   A O   1 
HETATM 4885 O  O   . HOH   Y 6 .   ? -26.571   1.470    -47.062   1.000 57.17034  ? 535 HOH   A O   1 
HETATM 4886 O  O   . HOH   Y 6 .   ? 12.19119  27.93548 -57.44274 1.000 63.98125  ? 536 HOH   A O   1 
HETATM 4887 O  O   . HOH   Y 6 .   ? 13.26075  14.97329 -44.74284 1.000 69.55407  ? 537 HOH   A O   1 
HETATM 4888 O  O   . HOH   Y 6 .   ? 1.29504   25.09614 -63.43596 1.000 59.37311  ? 538 HOH   A O   1 
HETATM 4889 O  O   . HOH   Y 6 .   ? -27.61038 20.02345 -41.95135 1.000 55.46297  ? 539 HOH   A O   1 
HETATM 4890 O  O   . HOH   Y 6 .   ? 1.09239   27.67392 -32.39253 1.000 54.90309  ? 540 HOH   A O   1 
HETATM 4891 O  O   . HOH   Y 6 .   ? -18.29969 26.78897 -44.02340 1.000 55.32141  ? 541 HOH   A O   1 
HETATM 4892 O  O   . HOH   Y 6 .   ? 0.51639   6.11152  -47.01869 1.000 58.16229  ? 542 HOH   A O   1 
HETATM 4893 O  O   . HOH   Y 6 .   ? -30.66060 10.72133 -49.00580 1.000 68.41314  ? 543 HOH   A O   1 
HETATM 4894 O  O   . HOH   Y 6 .   ? -1.37383  13.51146 -31.51217 1.000 64.56044  ? 544 HOH   A O   1 
HETATM 4895 O  O   . HOH   Y 6 .   ? -31.64771 20.88658 -26.59876 1.000 87.60906  ? 545 HOH   A O   1 
HETATM 4896 O  O   . HOH   Y 6 .   ? -11.48185 7.08436  -36.57943 1.000 53.25021  ? 546 HOH   A O   1 
HETATM 4897 O  O   . HOH   Y 6 .   ? -18.45339 18.36922 -25.58600 1.000 73.87712  ? 547 HOH   A O   1 
HETATM 4898 O  O   . HOH   Y 6 .   ? -7.41957  33.06270 -47.91699 1.000 66.89592  ? 548 HOH   A O   1 
HETATM 4899 O  O   . HOH   Y 6 .   ? -21.29765 9.56982  -36.17142 1.000 65.63865  ? 549 HOH   A O   1 
HETATM 4900 O  O   . HOH   Y 6 .   ? -21.06362 24.72338 -45.22101 1.000 68.93826  ? 550 HOH   A O   1 
HETATM 4901 O  O   . HOH   Y 6 .   ? -19.48780 11.51566 -33.04899 1.000 64.26316  ? 551 HOH   A O   1 
HETATM 4902 O  O   . HOH   Y 6 .   ? -19.20287 3.40949  -38.24813 1.000 91.93477  ? 552 HOH   A O   1 
HETATM 4903 O  O   . HOH   Y 6 .   ? -3.22986  33.09779 -47.77432 1.000 63.52935  ? 553 HOH   A O   1 
HETATM 4904 O  O   . HOH   Y 6 .   ? -31.86882 22.87733 -28.30065 1.000 66.58301  ? 554 HOH   A O   1 
HETATM 4905 O  O   . HOH   Y 6 .   ? -3.73204  35.94112 -47.75625 1.000 66.46412  ? 555 HOH   A O   1 
HETATM 4906 O  O   . HOH   Y 6 .   ? -30.84912 24.86142 -26.17399 1.000 77.02801  ? 556 HOH   A O   1 
HETATM 4907 O  O   . HOH   Y 6 .   ? -1.32517  29.75313 -60.88480 1.000 67.91788  ? 557 HOH   A O   1 
HETATM 4908 O  O   . HOH   Y 6 .   ? -18.40241 31.07348 -40.03525 1.000 56.07596  ? 558 HOH   A O   1 
HETATM 4909 O  O   . HOH   Y 6 .   ? -0.76631  6.53671  -55.06594 1.000 79.36493  ? 559 HOH   A O   1 
HETATM 4910 O  O   . HOH   Z 6 .   ? 17.68042  5.45838  -7.83086  1.000 75.86152  ? 501 HOH   B O   1 
HETATM 4911 O  O   . HOH   Z 6 .   ? -12.02392 22.01027 -3.35784  1.000 65.27652  ? 502 HOH   B O   1 
HETATM 4912 O  O   . HOH   Z 6 .   ? 15.45621  15.41209 -2.51741  1.000 79.03083  ? 503 HOH   B O   1 
HETATM 4913 O  O   . HOH   Z 6 .   ? 7.47294   1.30599  -17.49129 1.000 69.08102  ? 504 HOH   B O   1 
HETATM 4914 O  O   . HOH   Z 6 .   ? 19.31918  3.24204  -9.04400  1.000 77.84854  ? 505 HOH   B O   1 
HETATM 4915 O  O   . HOH   Z 6 .   ? 13.23566  11.77089 -24.77083 1.000 52.90851  ? 506 HOH   B O   1 
HETATM 4916 O  O   . HOH   Z 6 .   ? 12.89768  30.53009 -16.91846 1.000 77.56245  ? 507 HOH   B O   1 
HETATM 4917 O  O   . HOH   Z 6 .   ? 30.78088  15.82142 -27.16285 1.000 79.90611  ? 508 HOH   B O   1 
HETATM 4918 O  O   . HOH   Z 6 .   ? 12.17623  32.98488 -18.06769 1.000 61.44780  ? 509 HOH   B O   1 
HETATM 4919 O  O   . HOH   Z 6 .   ? 2.11098   11.88533 -28.89219 1.000 67.73984  ? 510 HOH   B O   1 
HETATM 4920 O  O   . HOH   Z 6 .   ? 25.95539  25.71094 -14.37558 1.000 68.80567  ? 511 HOH   B O   1 
HETATM 4921 O  O   . HOH   Z 6 .   ? -9.58411  12.33669 -26.99501 1.000 59.56040  ? 512 HOH   B O   1 
HETATM 4922 O  O   . HOH   Z 6 .   ? 17.36908  27.62335 -12.07255 1.000 83.60809  ? 513 HOH   B O   1 
HETATM 4923 O  O   . HOH   Z 6 .   ? 30.32700  26.59483 -30.17394 1.000 74.57874  ? 514 HOH   B O   1 
HETATM 4924 O  O   . HOH   Z 6 .   ? 32.29679  21.99071 -31.14072 1.000 82.25370  ? 515 HOH   B O   1 
HETATM 4925 O  O   . HOH   Z 6 .   ? -13.48659 23.07257 -13.20196 1.000 73.53261  ? 516 HOH   B O   1 
HETATM 4926 O  O   . HOH   Z 6 .   ? 38.02898  15.70514 -26.84514 1.000 65.69068  ? 517 HOH   B O   1 
HETATM 4927 O  O   . HOH   Z 6 .   ? 13.23408  6.29883  -25.23226 1.000 70.80623  ? 518 HOH   B O   1 
HETATM 4928 O  O   . HOH   Z 6 .   ? -18.48084 16.57623 -21.32745 1.000 84.24720  ? 519 HOH   B O   1 
HETATM 4929 O  O   . HOH   Z 6 .   ? -8.48593  25.90039 -19.86994 1.000 67.51482  ? 520 HOH   B O   1 
HETATM 4930 O  O   . HOH   Z 6 .   ? -12.25036 9.33941  -15.30790 1.000 72.61817  ? 521 HOH   B O   1 
HETATM 4931 O  O   . HOH   Z 6 .   ? 21.12478  0.90799  -10.28752 1.000 86.49675  ? 522 HOH   B O   1 
HETATM 4932 O  O   . HOH   Z 6 .   ? -6.86644  42.84409 1.16107   1.000 83.27805  ? 523 HOH   B O   1 
HETATM 4933 O  O   . HOH   Z 6 .   ? -6.75366  44.22548 -1.65324  1.000 95.92383  ? 524 HOH   B O   1 
HETATM 4934 O  O   . HOH   Z 6 .   ? -8.04915  30.98274 -23.47755 1.000 84.81598  ? 525 HOH   B O   1 
HETATM 4935 O  O   . HOH   Z 6 .   ? 18.52041  22.42359 -30.40831 1.000 77.83682  ? 526 HOH   B O   1 
HETATM 4936 O  O   . HOH   Z 6 .   ? 18.59297  28.23666 -14.69783 1.000 71.68051  ? 527 HOH   B O   1 
HETATM 4937 O  O   . HOH   Z 6 .   ? -10.17923 8.35507  -11.49081 1.000 64.64251  ? 528 HOH   B O   1 
HETATM 4938 O  O   . HOH   Z 6 .   ? 18.08034  13.76342 -29.97483 1.000 63.52825  ? 529 HOH   B O   1 
HETATM 4939 O  O   . HOH   Z 6 .   ? -6.89507  38.54077 5.75992   1.000 72.11848  ? 530 HOH   B O   1 
HETATM 4940 O  O   . HOH   Z 6 .   ? 34.986    -4.034   -5.418    1.000 68.58988  ? 531 HOH   B O   1 
HETATM 4941 O  O   . HOH   Z 6 .   ? 0.52286   48.66474 -10.37615 1.000 85.26986  ? 532 HOH   B O   1 
HETATM 4942 O  O   . HOH   Z 6 .   ? -4.27615  46.74408 -8.81801  1.000 87.48524  ? 533 HOH   B O   1 
# 
