data_9D2H
# 
_entry.id   9D2H 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9D2H         pdb_00009d2h 10.2210/pdb9d2h/pdb 
WWPDB D_1000287202 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-15 
2 'Structure model' 1 1 2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9D2H 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              smarius@uwm.edu 
_pdbx_contact_author.name_first         Marius 
_pdbx_contact_author.name_last          Schmidt 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0962-9468 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Schmidt, M.' 1 0000-0002-0962-9468 
'Malla, T.N.' 2 0000-0002-1387-0801 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Iucrj 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2052-2525 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            12 
_citation.language                  ? 
_citation.page_first                36 
_citation.page_last                 48 
_citation.title                     
'Exploiting fourth-generation synchrotron radiation for enzyme and photoreceptor characterization.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1107/S2052252524010868 
_citation.pdbx_database_id_PubMed   39575537 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Malla, T.N.'      1  ? 
primary 'Muniyappan, S.'   2  ? 
primary 'Menendez, D.'     3  ? 
primary 'Ogukwe, F.'       4  ? 
primary 'Dale, A.N.'       5  ? 
primary 'Clayton, J.D.'    6  ? 
primary 'Weatherall, D.D.' 7  ? 
primary 'Karki, P.'        8  ? 
primary 'Dangi, S.'        9  ? 
primary 'Mandella, V.'     10 ? 
primary 'Pacheco, A.A.'    11 ? 
primary 'Stojkovic, E.A.'  12 ? 
primary 'Rose, S.L.'       13 ? 
primary 'Orlans, J.'       14 ? 
primary 'Basu, S.'         15 ? 
primary 'de Sanctis, D.'   16 ? 
primary 'Schmidt, M.'      17 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'histidine kinase'     52822.488 2   2.7.13.3 ? ? ? 
2 non-polymer syn 'BILIVERDINE IX ALPHA' 582.646   2   ?        ? ? ? 
3 non-polymer syn BENZAMIDINE            120.152   1   ?        ? ? ? 
4 water       nat water                  18.015    381 ?        ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPPSVSELDLSQCDREPIHLLGGIQSHGVLLAFRGPDRLLEVVSANAQALLGRPPETLLGQPVGRVLPAEVLAQWEPLVA
RGSVRVVLPAGAYRALLHESDGLTVLELEPAELQPGMEETALEVVRRLVSPLAGVKGTQALLQTAADTVRALTGFDRVMV
YRFDADWHGEVLAESKRGGMDGFLGMHFPATDIPVQARALYTRNPLRLIADARARPVPLLPPVVPALGRPLDLSNSALRS
VSPVHLEYLRNMGVGASFSLSLLKEGVLWGLIACHHLEPLHISHERRRACEVLTQLLALQLSAEERAAEASEDAHRAALL
GQLATAMGEGGTLEEVLEKESERVLALTGAAGVALLLGEEPLLVGCTPAQDEVEALVAWLATQPFQTSFHTDRLGTVYPP
LAARADVAAGILAVRLAPAAARFAIWFRPEVARTISWAGNPRKPAEPEPGHQRLHPRGSFQAWEETVRDTSLPWKRADLG
AAEGFRGALV
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPPSVSELDLSQCDREPIHLLGGIQSHGVLLAFRGPDRLLEVVSANAQALLGRPPETLLGQPVGRVLPAEVLAQWEPLVA
RGSVRVVLPAGAYRALLHESDGLTVLELEPAELQPGMEETALEVVRRLVSPLAGVKGTQALLQTAADTVRALTGFDRVMV
YRFDADWHGEVLAESKRGGMDGFLGMHFPATDIPVQARALYTRNPLRLIADARARPVPLLPPVVPALGRPLDLSNSALRS
VSPVHLEYLRNMGVGASFSLSLLKEGVLWGLIACHHLEPLHISHERRRACEVLTQLLALQLSAEERAAEASEDAHRAALL
GQLATAMGEGGTLEEVLEKESERVLALTGAAGVALLLGEEPLLVGCTPAQDEVEALVAWLATQPFQTSFHTDRLGTVYPP
LAARADVAAGILAVRLAPAAARFAIWFRPEVARTISWAGNPRKPAEPEPGHQRLHPRGSFQAWEETVRDTSLPWKRADLG
AAEGFRGALV
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'BILIVERDINE IX ALPHA' BLA 
3 BENZAMIDINE            BEN 
4 water                  HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   PRO n 
1 4   SER n 
1 5   VAL n 
1 6   SER n 
1 7   GLU n 
1 8   LEU n 
1 9   ASP n 
1 10  LEU n 
1 11  SER n 
1 12  GLN n 
1 13  CYS n 
1 14  ASP n 
1 15  ARG n 
1 16  GLU n 
1 17  PRO n 
1 18  ILE n 
1 19  HIS n 
1 20  LEU n 
1 21  LEU n 
1 22  GLY n 
1 23  GLY n 
1 24  ILE n 
1 25  GLN n 
1 26  SER n 
1 27  HIS n 
1 28  GLY n 
1 29  VAL n 
1 30  LEU n 
1 31  LEU n 
1 32  ALA n 
1 33  PHE n 
1 34  ARG n 
1 35  GLY n 
1 36  PRO n 
1 37  ASP n 
1 38  ARG n 
1 39  LEU n 
1 40  LEU n 
1 41  GLU n 
1 42  VAL n 
1 43  VAL n 
1 44  SER n 
1 45  ALA n 
1 46  ASN n 
1 47  ALA n 
1 48  GLN n 
1 49  ALA n 
1 50  LEU n 
1 51  LEU n 
1 52  GLY n 
1 53  ARG n 
1 54  PRO n 
1 55  PRO n 
1 56  GLU n 
1 57  THR n 
1 58  LEU n 
1 59  LEU n 
1 60  GLY n 
1 61  GLN n 
1 62  PRO n 
1 63  VAL n 
1 64  GLY n 
1 65  ARG n 
1 66  VAL n 
1 67  LEU n 
1 68  PRO n 
1 69  ALA n 
1 70  GLU n 
1 71  VAL n 
1 72  LEU n 
1 73  ALA n 
1 74  GLN n 
1 75  TRP n 
1 76  GLU n 
1 77  PRO n 
1 78  LEU n 
1 79  VAL n 
1 80  ALA n 
1 81  ARG n 
1 82  GLY n 
1 83  SER n 
1 84  VAL n 
1 85  ARG n 
1 86  VAL n 
1 87  VAL n 
1 88  LEU n 
1 89  PRO n 
1 90  ALA n 
1 91  GLY n 
1 92  ALA n 
1 93  TYR n 
1 94  ARG n 
1 95  ALA n 
1 96  LEU n 
1 97  LEU n 
1 98  HIS n 
1 99  GLU n 
1 100 SER n 
1 101 ASP n 
1 102 GLY n 
1 103 LEU n 
1 104 THR n 
1 105 VAL n 
1 106 LEU n 
1 107 GLU n 
1 108 LEU n 
1 109 GLU n 
1 110 PRO n 
1 111 ALA n 
1 112 GLU n 
1 113 LEU n 
1 114 GLN n 
1 115 PRO n 
1 116 GLY n 
1 117 MET n 
1 118 GLU n 
1 119 GLU n 
1 120 THR n 
1 121 ALA n 
1 122 LEU n 
1 123 GLU n 
1 124 VAL n 
1 125 VAL n 
1 126 ARG n 
1 127 ARG n 
1 128 LEU n 
1 129 VAL n 
1 130 SER n 
1 131 PRO n 
1 132 LEU n 
1 133 ALA n 
1 134 GLY n 
1 135 VAL n 
1 136 LYS n 
1 137 GLY n 
1 138 THR n 
1 139 GLN n 
1 140 ALA n 
1 141 LEU n 
1 142 LEU n 
1 143 GLN n 
1 144 THR n 
1 145 ALA n 
1 146 ALA n 
1 147 ASP n 
1 148 THR n 
1 149 VAL n 
1 150 ARG n 
1 151 ALA n 
1 152 LEU n 
1 153 THR n 
1 154 GLY n 
1 155 PHE n 
1 156 ASP n 
1 157 ARG n 
1 158 VAL n 
1 159 MET n 
1 160 VAL n 
1 161 TYR n 
1 162 ARG n 
1 163 PHE n 
1 164 ASP n 
1 165 ALA n 
1 166 ASP n 
1 167 TRP n 
1 168 HIS n 
1 169 GLY n 
1 170 GLU n 
1 171 VAL n 
1 172 LEU n 
1 173 ALA n 
1 174 GLU n 
1 175 SER n 
1 176 LYS n 
1 177 ARG n 
1 178 GLY n 
1 179 GLY n 
1 180 MET n 
1 181 ASP n 
1 182 GLY n 
1 183 PHE n 
1 184 LEU n 
1 185 GLY n 
1 186 MET n 
1 187 HIS n 
1 188 PHE n 
1 189 PRO n 
1 190 ALA n 
1 191 THR n 
1 192 ASP n 
1 193 ILE n 
1 194 PRO n 
1 195 VAL n 
1 196 GLN n 
1 197 ALA n 
1 198 ARG n 
1 199 ALA n 
1 200 LEU n 
1 201 TYR n 
1 202 THR n 
1 203 ARG n 
1 204 ASN n 
1 205 PRO n 
1 206 LEU n 
1 207 ARG n 
1 208 LEU n 
1 209 ILE n 
1 210 ALA n 
1 211 ASP n 
1 212 ALA n 
1 213 ARG n 
1 214 ALA n 
1 215 ARG n 
1 216 PRO n 
1 217 VAL n 
1 218 PRO n 
1 219 LEU n 
1 220 LEU n 
1 221 PRO n 
1 222 PRO n 
1 223 VAL n 
1 224 VAL n 
1 225 PRO n 
1 226 ALA n 
1 227 LEU n 
1 228 GLY n 
1 229 ARG n 
1 230 PRO n 
1 231 LEU n 
1 232 ASP n 
1 233 LEU n 
1 234 SER n 
1 235 ASN n 
1 236 SER n 
1 237 ALA n 
1 238 LEU n 
1 239 ARG n 
1 240 SER n 
1 241 VAL n 
1 242 SER n 
1 243 PRO n 
1 244 VAL n 
1 245 HIS n 
1 246 LEU n 
1 247 GLU n 
1 248 TYR n 
1 249 LEU n 
1 250 ARG n 
1 251 ASN n 
1 252 MET n 
1 253 GLY n 
1 254 VAL n 
1 255 GLY n 
1 256 ALA n 
1 257 SER n 
1 258 PHE n 
1 259 SER n 
1 260 LEU n 
1 261 SER n 
1 262 LEU n 
1 263 LEU n 
1 264 LYS n 
1 265 GLU n 
1 266 GLY n 
1 267 VAL n 
1 268 LEU n 
1 269 TRP n 
1 270 GLY n 
1 271 LEU n 
1 272 ILE n 
1 273 ALA n 
1 274 CYS n 
1 275 HIS n 
1 276 HIS n 
1 277 LEU n 
1 278 GLU n 
1 279 PRO n 
1 280 LEU n 
1 281 HIS n 
1 282 ILE n 
1 283 SER n 
1 284 HIS n 
1 285 GLU n 
1 286 ARG n 
1 287 ARG n 
1 288 ARG n 
1 289 ALA n 
1 290 CYS n 
1 291 GLU n 
1 292 VAL n 
1 293 LEU n 
1 294 THR n 
1 295 GLN n 
1 296 LEU n 
1 297 LEU n 
1 298 ALA n 
1 299 LEU n 
1 300 GLN n 
1 301 LEU n 
1 302 SER n 
1 303 ALA n 
1 304 GLU n 
1 305 GLU n 
1 306 ARG n 
1 307 ALA n 
1 308 ALA n 
1 309 GLU n 
1 310 ALA n 
1 311 SER n 
1 312 GLU n 
1 313 ASP n 
1 314 ALA n 
1 315 HIS n 
1 316 ARG n 
1 317 ALA n 
1 318 ALA n 
1 319 LEU n 
1 320 LEU n 
1 321 GLY n 
1 322 GLN n 
1 323 LEU n 
1 324 ALA n 
1 325 THR n 
1 326 ALA n 
1 327 MET n 
1 328 GLY n 
1 329 GLU n 
1 330 GLY n 
1 331 GLY n 
1 332 THR n 
1 333 LEU n 
1 334 GLU n 
1 335 GLU n 
1 336 VAL n 
1 337 LEU n 
1 338 GLU n 
1 339 LYS n 
1 340 GLU n 
1 341 SER n 
1 342 GLU n 
1 343 ARG n 
1 344 VAL n 
1 345 LEU n 
1 346 ALA n 
1 347 LEU n 
1 348 THR n 
1 349 GLY n 
1 350 ALA n 
1 351 ALA n 
1 352 GLY n 
1 353 VAL n 
1 354 ALA n 
1 355 LEU n 
1 356 LEU n 
1 357 LEU n 
1 358 GLY n 
1 359 GLU n 
1 360 GLU n 
1 361 PRO n 
1 362 LEU n 
1 363 LEU n 
1 364 VAL n 
1 365 GLY n 
1 366 CYS n 
1 367 THR n 
1 368 PRO n 
1 369 ALA n 
1 370 GLN n 
1 371 ASP n 
1 372 GLU n 
1 373 VAL n 
1 374 GLU n 
1 375 ALA n 
1 376 LEU n 
1 377 VAL n 
1 378 ALA n 
1 379 TRP n 
1 380 LEU n 
1 381 ALA n 
1 382 THR n 
1 383 GLN n 
1 384 PRO n 
1 385 PHE n 
1 386 GLN n 
1 387 THR n 
1 388 SER n 
1 389 PHE n 
1 390 HIS n 
1 391 THR n 
1 392 ASP n 
1 393 ARG n 
1 394 LEU n 
1 395 GLY n 
1 396 THR n 
1 397 VAL n 
1 398 TYR n 
1 399 PRO n 
1 400 PRO n 
1 401 LEU n 
1 402 ALA n 
1 403 ALA n 
1 404 ARG n 
1 405 ALA n 
1 406 ASP n 
1 407 VAL n 
1 408 ALA n 
1 409 ALA n 
1 410 GLY n 
1 411 ILE n 
1 412 LEU n 
1 413 ALA n 
1 414 VAL n 
1 415 ARG n 
1 416 LEU n 
1 417 ALA n 
1 418 PRO n 
1 419 ALA n 
1 420 ALA n 
1 421 ALA n 
1 422 ARG n 
1 423 PHE n 
1 424 ALA n 
1 425 ILE n 
1 426 TRP n 
1 427 PHE n 
1 428 ARG n 
1 429 PRO n 
1 430 GLU n 
1 431 VAL n 
1 432 ALA n 
1 433 ARG n 
1 434 THR n 
1 435 ILE n 
1 436 SER n 
1 437 TRP n 
1 438 ALA n 
1 439 GLY n 
1 440 ASN n 
1 441 PRO n 
1 442 ARG n 
1 443 LYS n 
1 444 PRO n 
1 445 ALA n 
1 446 GLU n 
1 447 PRO n 
1 448 GLU n 
1 449 PRO n 
1 450 GLY n 
1 451 HIS n 
1 452 GLN n 
1 453 ARG n 
1 454 LEU n 
1 455 HIS n 
1 456 PRO n 
1 457 ARG n 
1 458 GLY n 
1 459 SER n 
1 460 PHE n 
1 461 GLN n 
1 462 ALA n 
1 463 TRP n 
1 464 GLU n 
1 465 GLU n 
1 466 THR n 
1 467 VAL n 
1 468 ARG n 
1 469 ASP n 
1 470 THR n 
1 471 SER n 
1 472 LEU n 
1 473 PRO n 
1 474 TRP n 
1 475 LYS n 
1 476 ARG n 
1 477 ALA n 
1 478 ASP n 
1 479 LEU n 
1 480 GLY n 
1 481 ALA n 
1 482 ALA n 
1 483 GLU n 
1 484 GLY n 
1 485 PHE n 
1 486 ARG n 
1 487 GLY n 
1 488 ALA n 
1 489 LEU n 
1 490 VAL n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   490 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 STIAU_8420 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Stigmatella aurantiaca' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     41 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE               ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE             ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'        ? 'C4 H7 N O4'     133.103 
BEN non-polymer         . BENZAMIDINE            ? 'C7 H8 N2'       120.152 
BLA non-polymer         . 'BILIVERDINE IX ALPHA' ? 'C33 H34 N4 O6'  582.646 
CYS 'L-peptide linking' y CYSTEINE               ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE              ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'        ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE              ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                  ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE             ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                 ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE             ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE          ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                 ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE              ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN             ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE               ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                 ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   PRO 2   2   ?   ?   ?   A . n 
A 1 3   PRO 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   ?   ?   ?   A . n 
A 1 5   VAL 5   5   ?   ?   ?   A . n 
A 1 6   SER 6   6   ?   ?   ?   A . n 
A 1 7   GLU 7   7   ?   ?   ?   A . n 
A 1 8   LEU 8   8   ?   ?   ?   A . n 
A 1 9   ASP 9   9   9   ASP ASP A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  SER 11  11  11  SER SER A . n 
A 1 12  GLN 12  12  12  GLN GLN A . n 
A 1 13  CYS 13  13  13  CYS CYS A . n 
A 1 14  ASP 14  14  14  ASP ASP A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  GLU 16  16  16  GLU GLU A . n 
A 1 17  PRO 17  17  17  PRO PRO A . n 
A 1 18  ILE 18  18  18  ILE ILE A . n 
A 1 19  HIS 19  19  19  HIS HIS A . n 
A 1 20  LEU 20  20  20  LEU LEU A . n 
A 1 21  LEU 21  21  21  LEU LEU A . n 
A 1 22  GLY 22  22  22  GLY GLY A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  GLN 25  25  25  GLN GLN A . n 
A 1 26  SER 26  26  26  SER SER A . n 
A 1 27  HIS 27  27  27  HIS HIS A . n 
A 1 28  GLY 28  28  28  GLY GLY A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  ALA 32  32  32  ALA ALA A . n 
A 1 33  PHE 33  33  33  PHE PHE A . n 
A 1 34  ARG 34  34  34  ARG ARG A . n 
A 1 35  GLY 35  35  35  GLY GLY A . n 
A 1 36  PRO 36  36  36  PRO PRO A . n 
A 1 37  ASP 37  37  37  ASP ASP A . n 
A 1 38  ARG 38  38  38  ARG ARG A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  GLU 41  41  41  GLU GLU A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  SER 44  44  44  SER SER A . n 
A 1 45  ALA 45  45  45  ALA ALA A . n 
A 1 46  ASN 46  46  46  ASN ASN A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  GLN 48  48  48  GLN GLN A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  LEU 51  51  51  LEU LEU A . n 
A 1 52  GLY 52  52  52  GLY GLY A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  PRO 55  55  55  PRO PRO A . n 
A 1 56  GLU 56  56  56  GLU GLU A . n 
A 1 57  THR 57  57  57  THR THR A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  GLN 61  61  61  GLN GLN A . n 
A 1 62  PRO 62  62  62  PRO PRO A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  GLY 64  64  64  GLY GLY A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  VAL 66  66  66  VAL VAL A . n 
A 1 67  LEU 67  67  67  LEU LEU A . n 
A 1 68  PRO 68  68  68  PRO PRO A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  ALA 73  73  73  ALA ALA A . n 
A 1 74  GLN 74  74  74  GLN GLN A . n 
A 1 75  TRP 75  75  75  TRP TRP A . n 
A 1 76  GLU 76  76  76  GLU GLU A . n 
A 1 77  PRO 77  77  77  PRO PRO A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  VAL 79  79  79  VAL VAL A . n 
A 1 80  ALA 80  80  80  ALA ALA A . n 
A 1 81  ARG 81  81  81  ARG ARG A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  SER 83  83  83  SER SER A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  ARG 85  85  85  ARG ARG A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  VAL 87  87  87  VAL VAL A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  TYR 93  93  93  TYR TYR A . n 
A 1 94  ARG 94  94  94  ARG ARG A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  HIS 98  98  98  HIS HIS A . n 
A 1 99  GLU 99  99  99  GLU GLU A . n 
A 1 100 SER 100 100 100 SER SER A . n 
A 1 101 ASP 101 101 101 ASP ASP A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 THR 104 104 104 THR THR A . n 
A 1 105 VAL 105 105 105 VAL VAL A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 PRO 110 110 110 PRO PRO A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 GLU 112 112 112 GLU GLU A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 GLN 114 114 114 GLN GLN A . n 
A 1 115 PRO 115 115 115 PRO PRO A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 MET 117 117 117 MET MET A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 GLU 119 119 119 GLU GLU A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 GLU 123 123 123 GLU GLU A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 ARG 126 126 126 ARG ARG A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 LEU 128 128 128 LEU LEU A . n 
A 1 129 VAL 129 129 129 VAL VAL A . n 
A 1 130 SER 130 130 130 SER SER A . n 
A 1 131 PRO 131 131 131 PRO PRO A . n 
A 1 132 LEU 132 132 132 LEU LEU A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 LYS 136 136 136 LYS LYS A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 THR 138 138 138 THR THR A . n 
A 1 139 GLN 139 139 139 GLN GLN A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 GLN 143 143 143 GLN GLN A . n 
A 1 144 THR 144 144 144 THR THR A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 THR 148 148 148 THR THR A . n 
A 1 149 VAL 149 149 149 VAL VAL A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 THR 153 153 153 THR THR A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 PHE 155 155 155 PHE PHE A . n 
A 1 156 ASP 156 156 156 ASP ASP A . n 
A 1 157 ARG 157 157 157 ARG ARG A . n 
A 1 158 VAL 158 158 158 VAL VAL A . n 
A 1 159 MET 159 159 159 MET MET A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 TYR 161 161 161 TYR TYR A . n 
A 1 162 ARG 162 162 162 ARG ARG A . n 
A 1 163 PHE 163 163 163 PHE PHE A . n 
A 1 164 ASP 164 164 164 ASP ASP A . n 
A 1 165 ALA 165 165 165 ALA ALA A . n 
A 1 166 ASP 166 166 166 ASP ASP A . n 
A 1 167 TRP 167 167 167 TRP TRP A . n 
A 1 168 HIS 168 168 168 HIS HIS A . n 
A 1 169 GLY 169 169 169 GLY GLY A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 VAL 171 171 171 VAL VAL A . n 
A 1 172 LEU 172 172 172 LEU LEU A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 SER 175 175 175 SER SER A . n 
A 1 176 LYS 176 176 176 LYS LYS A . n 
A 1 177 ARG 177 177 177 ARG ARG A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 MET 180 180 180 MET MET A . n 
A 1 181 ASP 181 181 181 ASP ASP A . n 
A 1 182 GLY 182 182 182 GLY GLY A . n 
A 1 183 PHE 183 183 183 PHE PHE A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 MET 186 186 186 MET MET A . n 
A 1 187 HIS 187 187 187 HIS HIS A . n 
A 1 188 PHE 188 188 188 PHE PHE A . n 
A 1 189 PRO 189 189 189 PRO PRO A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 THR 191 191 191 THR THR A . n 
A 1 192 ASP 192 192 192 ASP ASP A . n 
A 1 193 ILE 193 193 193 ILE ILE A . n 
A 1 194 PRO 194 194 194 PRO PRO A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 GLN 196 196 196 GLN GLN A . n 
A 1 197 ALA 197 197 197 ALA ALA A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 ALA 199 199 199 ALA ALA A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 TYR 201 201 201 TYR TYR A . n 
A 1 202 THR 202 202 202 THR THR A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 ASN 204 204 204 ASN ASN A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 ARG 207 207 207 ARG ARG A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 ILE 209 209 209 ILE ILE A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 ASP 211 211 211 ASP ASP A . n 
A 1 212 ALA 212 212 212 ALA ALA A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 ARG 215 215 215 ARG ARG A . n 
A 1 216 PRO 216 216 216 PRO PRO A . n 
A 1 217 VAL 217 217 217 VAL VAL A . n 
A 1 218 PRO 218 218 218 PRO PRO A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 PRO 221 221 221 PRO PRO A . n 
A 1 222 PRO 222 222 222 PRO PRO A . n 
A 1 223 VAL 223 223 223 VAL VAL A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 PRO 225 225 225 PRO PRO A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 PRO 230 230 230 PRO PRO A . n 
A 1 231 LEU 231 231 231 LEU LEU A . n 
A 1 232 ASP 232 232 232 ASP ASP A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 SER 234 234 234 SER SER A . n 
A 1 235 ASN 235 235 235 ASN ASN A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 LEU 238 238 238 LEU LEU A . n 
A 1 239 ARG 239 239 239 ARG ARG A . n 
A 1 240 SER 240 240 240 SER SER A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 SER 242 242 242 SER SER A . n 
A 1 243 PRO 243 243 243 PRO PRO A . n 
A 1 244 VAL 244 244 244 VAL VAL A . n 
A 1 245 HIS 245 245 245 HIS HIS A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 GLU 247 247 247 GLU GLU A . n 
A 1 248 TYR 248 248 248 TYR TYR A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 ARG 250 250 250 ARG ARG A . n 
A 1 251 ASN 251 251 251 ASN ASN A . n 
A 1 252 MET 252 252 252 MET MET A . n 
A 1 253 GLY 253 253 253 GLY GLY A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 GLY 255 255 255 GLY GLY A . n 
A 1 256 ALA 256 256 256 ALA ALA A . n 
A 1 257 SER 257 257 257 SER SER A . n 
A 1 258 PHE 258 258 258 PHE PHE A . n 
A 1 259 SER 259 259 259 SER SER A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 LYS 264 264 264 LYS LYS A . n 
A 1 265 GLU 265 265 265 GLU GLU A . n 
A 1 266 GLY 266 266 266 GLY GLY A . n 
A 1 267 VAL 267 267 267 VAL VAL A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 TRP 269 269 269 TRP TRP A . n 
A 1 270 GLY 270 270 270 GLY GLY A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 ILE 272 272 272 ILE ILE A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 CYS 274 274 274 CYS CYS A . n 
A 1 275 HIS 275 275 275 HIS HIS A . n 
A 1 276 HIS 276 276 276 HIS HIS A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 GLU 278 278 278 GLU GLU A . n 
A 1 279 PRO 279 279 279 PRO PRO A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 HIS 281 281 281 HIS HIS A . n 
A 1 282 ILE 282 282 282 ILE ILE A . n 
A 1 283 SER 283 283 283 SER SER A . n 
A 1 284 HIS 284 284 284 HIS HIS A . n 
A 1 285 GLU 285 285 285 GLU GLU A . n 
A 1 286 ARG 286 286 286 ARG ARG A . n 
A 1 287 ARG 287 287 287 ARG ARG A . n 
A 1 288 ARG 288 288 288 ARG ARG A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 CYS 290 290 290 CYS CYS A . n 
A 1 291 GLU 291 291 291 GLU GLU A . n 
A 1 292 VAL 292 292 292 VAL VAL A . n 
A 1 293 LEU 293 293 293 LEU LEU A . n 
A 1 294 THR 294 294 294 THR THR A . n 
A 1 295 GLN 295 295 295 GLN GLN A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 ALA 298 298 298 ALA ALA A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 GLN 300 300 300 GLN GLN A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 SER 302 302 302 SER SER A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 GLU 304 304 304 GLU GLU A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 ARG 306 306 306 ARG ARG A . n 
A 1 307 ALA 307 307 307 ALA ALA A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 GLU 309 309 309 GLU GLU A . n 
A 1 310 ALA 310 310 310 ALA ALA A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 GLU 312 312 312 GLU GLU A . n 
A 1 313 ASP 313 313 313 ASP ASP A . n 
A 1 314 ALA 314 314 314 ALA ALA A . n 
A 1 315 HIS 315 315 315 HIS HIS A . n 
A 1 316 ARG 316 316 316 ARG ARG A . n 
A 1 317 ALA 317 317 317 ALA ALA A . n 
A 1 318 ALA 318 318 318 ALA ALA A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 LEU 320 320 320 LEU LEU A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 GLN 322 322 322 GLN GLN A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 ALA 324 324 324 ALA ALA A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 MET 327 327 327 MET MET A . n 
A 1 328 GLY 328 328 328 GLY GLY A . n 
A 1 329 GLU 329 329 329 GLU GLU A . n 
A 1 330 GLY 330 330 330 GLY GLY A . n 
A 1 331 GLY 331 331 331 GLY GLY A . n 
A 1 332 THR 332 332 332 THR THR A . n 
A 1 333 LEU 333 333 333 LEU LEU A . n 
A 1 334 GLU 334 334 334 GLU GLU A . n 
A 1 335 GLU 335 335 335 GLU GLU A . n 
A 1 336 VAL 336 336 336 VAL VAL A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 GLU 338 338 338 GLU GLU A . n 
A 1 339 LYS 339 339 339 LYS LYS A . n 
A 1 340 GLU 340 340 340 GLU GLU A . n 
A 1 341 SER 341 341 341 SER SER A . n 
A 1 342 GLU 342 342 342 GLU GLU A . n 
A 1 343 ARG 343 343 343 ARG ARG A . n 
A 1 344 VAL 344 344 344 VAL VAL A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 ALA 346 346 346 ALA ALA A . n 
A 1 347 LEU 347 347 347 LEU LEU A . n 
A 1 348 THR 348 348 348 THR THR A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 ALA 351 351 351 ALA ALA A . n 
A 1 352 GLY 352 352 352 GLY GLY A . n 
A 1 353 VAL 353 353 353 VAL VAL A . n 
A 1 354 ALA 354 354 354 ALA ALA A . n 
A 1 355 LEU 355 355 355 LEU LEU A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 GLY 358 358 358 GLY GLY A . n 
A 1 359 GLU 359 359 359 GLU GLU A . n 
A 1 360 GLU 360 360 360 GLU GLU A . n 
A 1 361 PRO 361 361 361 PRO PRO A . n 
A 1 362 LEU 362 362 362 LEU LEU A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 VAL 364 364 364 VAL VAL A . n 
A 1 365 GLY 365 365 365 GLY GLY A . n 
A 1 366 CYS 366 366 366 CYS CYS A . n 
A 1 367 THR 367 367 367 THR THR A . n 
A 1 368 PRO 368 368 368 PRO PRO A . n 
A 1 369 ALA 369 369 369 ALA ALA A . n 
A 1 370 GLN 370 370 370 GLN GLN A . n 
A 1 371 ASP 371 371 371 ASP ASP A . n 
A 1 372 GLU 372 372 372 GLU GLU A . n 
A 1 373 VAL 373 373 373 VAL VAL A . n 
A 1 374 GLU 374 374 374 GLU GLU A . n 
A 1 375 ALA 375 375 375 ALA ALA A . n 
A 1 376 LEU 376 376 376 LEU LEU A . n 
A 1 377 VAL 377 377 377 VAL VAL A . n 
A 1 378 ALA 378 378 378 ALA ALA A . n 
A 1 379 TRP 379 379 379 TRP TRP A . n 
A 1 380 LEU 380 380 380 LEU LEU A . n 
A 1 381 ALA 381 381 381 ALA ALA A . n 
A 1 382 THR 382 382 382 THR THR A . n 
A 1 383 GLN 383 383 383 GLN GLN A . n 
A 1 384 PRO 384 384 384 PRO PRO A . n 
A 1 385 PHE 385 385 385 PHE PHE A . n 
A 1 386 GLN 386 386 386 GLN GLN A . n 
A 1 387 THR 387 387 387 THR THR A . n 
A 1 388 SER 388 388 388 SER SER A . n 
A 1 389 PHE 389 389 389 PHE PHE A . n 
A 1 390 HIS 390 390 390 HIS HIS A . n 
A 1 391 THR 391 391 391 THR THR A . n 
A 1 392 ASP 392 392 392 ASP ASP A . n 
A 1 393 ARG 393 393 393 ARG ARG A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 GLY 395 395 395 GLY GLY A . n 
A 1 396 THR 396 396 396 THR THR A . n 
A 1 397 VAL 397 397 397 VAL VAL A . n 
A 1 398 TYR 398 398 398 TYR TYR A . n 
A 1 399 PRO 399 399 399 PRO PRO A . n 
A 1 400 PRO 400 400 400 PRO PRO A . n 
A 1 401 LEU 401 401 401 LEU LEU A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 ALA 403 403 403 ALA ALA A . n 
A 1 404 ARG 404 404 404 ARG ARG A . n 
A 1 405 ALA 405 405 405 ALA ALA A . n 
A 1 406 ASP 406 406 406 ASP ASP A . n 
A 1 407 VAL 407 407 407 VAL VAL A . n 
A 1 408 ALA 408 408 408 ALA ALA A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 GLY 410 410 410 GLY GLY A . n 
A 1 411 ILE 411 411 411 ILE ILE A . n 
A 1 412 LEU 412 412 412 LEU LEU A . n 
A 1 413 ALA 413 413 413 ALA ALA A . n 
A 1 414 VAL 414 414 414 VAL VAL A . n 
A 1 415 ARG 415 415 415 ARG ARG A . n 
A 1 416 LEU 416 416 416 LEU LEU A . n 
A 1 417 ALA 417 417 417 ALA ALA A . n 
A 1 418 PRO 418 418 418 PRO PRO A . n 
A 1 419 ALA 419 419 419 ALA ALA A . n 
A 1 420 ALA 420 420 420 ALA ALA A . n 
A 1 421 ALA 421 421 421 ALA ALA A . n 
A 1 422 ARG 422 422 422 ARG ARG A . n 
A 1 423 PHE 423 423 423 PHE PHE A . n 
A 1 424 ALA 424 424 424 ALA ALA A . n 
A 1 425 ILE 425 425 425 ILE ILE A . n 
A 1 426 TRP 426 426 426 TRP TRP A . n 
A 1 427 PHE 427 427 427 PHE PHE A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 PRO 429 429 429 PRO PRO A . n 
A 1 430 GLU 430 430 430 GLU GLU A . n 
A 1 431 VAL 431 431 431 VAL VAL A . n 
A 1 432 ALA 432 432 432 ALA ALA A . n 
A 1 433 ARG 433 433 433 ARG ARG A . n 
A 1 434 THR 434 434 434 THR THR A . n 
A 1 435 ILE 435 435 435 ILE ILE A . n 
A 1 436 SER 436 436 436 SER SER A . n 
A 1 437 TRP 437 437 437 TRP TRP A . n 
A 1 438 ALA 438 438 438 ALA ALA A . n 
A 1 439 GLY 439 439 439 GLY GLY A . n 
A 1 440 ASN 440 440 440 ASN ASN A . n 
A 1 441 PRO 441 441 441 PRO PRO A . n 
A 1 442 ARG 442 442 442 ARG ARG A . n 
A 1 443 LYS 443 443 443 LYS LYS A . n 
A 1 444 PRO 444 444 444 PRO PRO A . n 
A 1 445 ALA 445 445 445 ALA ALA A . n 
A 1 446 GLU 446 446 446 GLU GLU A . n 
A 1 447 PRO 447 447 447 PRO PRO A . n 
A 1 448 GLU 448 448 448 GLU GLU A . n 
A 1 449 PRO 449 449 449 PRO PRO A . n 
A 1 450 GLY 450 450 450 GLY GLY A . n 
A 1 451 HIS 451 451 451 HIS HIS A . n 
A 1 452 GLN 452 452 452 GLN GLN A . n 
A 1 453 ARG 453 453 453 ARG ARG A . n 
A 1 454 LEU 454 454 454 LEU LEU A . n 
A 1 455 HIS 455 455 455 HIS HIS A . n 
A 1 456 PRO 456 456 456 PRO PRO A . n 
A 1 457 ARG 457 457 457 ARG ARG A . n 
A 1 458 GLY 458 458 458 GLY GLY A . n 
A 1 459 SER 459 459 459 SER SER A . n 
A 1 460 PHE 460 460 460 PHE PHE A . n 
A 1 461 GLN 461 461 461 GLN GLN A . n 
A 1 462 ALA 462 462 462 ALA ALA A . n 
A 1 463 TRP 463 463 463 TRP TRP A . n 
A 1 464 GLU 464 464 464 GLU GLU A . n 
A 1 465 GLU 465 465 465 GLU GLU A . n 
A 1 466 THR 466 466 466 THR THR A . n 
A 1 467 VAL 467 467 467 VAL VAL A . n 
A 1 468 ARG 468 468 468 ARG ARG A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 THR 470 470 470 THR THR A . n 
A 1 471 SER 471 471 471 SER SER A . n 
A 1 472 LEU 472 472 472 LEU LEU A . n 
A 1 473 PRO 473 473 473 PRO PRO A . n 
A 1 474 TRP 474 474 474 TRP TRP A . n 
A 1 475 LYS 475 475 475 LYS LYS A . n 
A 1 476 ARG 476 476 476 ARG ARG A . n 
A 1 477 ALA 477 477 477 ALA ALA A . n 
A 1 478 ASP 478 478 478 ASP ASP A . n 
A 1 479 LEU 479 479 479 LEU LEU A . n 
A 1 480 GLY 480 480 480 GLY GLY A . n 
A 1 481 ALA 481 481 481 ALA ALA A . n 
A 1 482 ALA 482 482 482 ALA ALA A . n 
A 1 483 GLU 483 483 483 GLU GLU A . n 
A 1 484 GLY 484 484 484 GLY GLY A . n 
A 1 485 PHE 485 485 485 PHE PHE A . n 
A 1 486 ARG 486 486 486 ARG ARG A . n 
A 1 487 GLY 487 487 487 GLY GLY A . n 
A 1 488 ALA 488 488 488 ALA ALA A . n 
A 1 489 LEU 489 489 489 LEU LEU A . n 
A 1 490 VAL 490 490 490 VAL VAL A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   PRO 2   2   ?   ?   ?   B . n 
B 1 3   PRO 3   3   ?   ?   ?   B . n 
B 1 4   SER 4   4   ?   ?   ?   B . n 
B 1 5   VAL 5   5   ?   ?   ?   B . n 
B 1 6   SER 6   6   ?   ?   ?   B . n 
B 1 7   GLU 7   7   ?   ?   ?   B . n 
B 1 8   LEU 8   8   ?   ?   ?   B . n 
B 1 9   ASP 9   9   9   ASP ASP B . n 
B 1 10  LEU 10  10  10  LEU LEU B . n 
B 1 11  SER 11  11  11  SER SER B . n 
B 1 12  GLN 12  12  12  GLN GLN B . n 
B 1 13  CYS 13  13  13  CYS CYS B . n 
B 1 14  ASP 14  14  14  ASP ASP B . n 
B 1 15  ARG 15  15  15  ARG ARG B . n 
B 1 16  GLU 16  16  16  GLU GLU B . n 
B 1 17  PRO 17  17  17  PRO PRO B . n 
B 1 18  ILE 18  18  18  ILE ILE B . n 
B 1 19  HIS 19  19  19  HIS HIS B . n 
B 1 20  LEU 20  20  20  LEU LEU B . n 
B 1 21  LEU 21  21  21  LEU LEU B . n 
B 1 22  GLY 22  22  22  GLY GLY B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  GLN 25  25  25  GLN GLN B . n 
B 1 26  SER 26  26  26  SER SER B . n 
B 1 27  HIS 27  27  27  HIS HIS B . n 
B 1 28  GLY 28  28  28  GLY GLY B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  LEU 31  31  31  LEU LEU B . n 
B 1 32  ALA 32  32  32  ALA ALA B . n 
B 1 33  PHE 33  33  33  PHE PHE B . n 
B 1 34  ARG 34  34  34  ARG ARG B . n 
B 1 35  GLY 35  35  35  GLY GLY B . n 
B 1 36  PRO 36  36  36  PRO PRO B . n 
B 1 37  ASP 37  37  37  ASP ASP B . n 
B 1 38  ARG 38  38  38  ARG ARG B . n 
B 1 39  LEU 39  39  39  LEU LEU B . n 
B 1 40  LEU 40  40  40  LEU LEU B . n 
B 1 41  GLU 41  41  41  GLU GLU B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  VAL 43  43  43  VAL VAL B . n 
B 1 44  SER 44  44  44  SER SER B . n 
B 1 45  ALA 45  45  45  ALA ALA B . n 
B 1 46  ASN 46  46  46  ASN ASN B . n 
B 1 47  ALA 47  47  47  ALA ALA B . n 
B 1 48  GLN 48  48  48  GLN GLN B . n 
B 1 49  ALA 49  49  49  ALA ALA B . n 
B 1 50  LEU 50  50  50  LEU LEU B . n 
B 1 51  LEU 51  51  51  LEU LEU B . n 
B 1 52  GLY 52  52  52  GLY GLY B . n 
B 1 53  ARG 53  53  53  ARG ARG B . n 
B 1 54  PRO 54  54  54  PRO PRO B . n 
B 1 55  PRO 55  55  55  PRO PRO B . n 
B 1 56  GLU 56  56  56  GLU GLU B . n 
B 1 57  THR 57  57  57  THR THR B . n 
B 1 58  LEU 58  58  58  LEU LEU B . n 
B 1 59  LEU 59  59  59  LEU LEU B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  GLN 61  61  61  GLN GLN B . n 
B 1 62  PRO 62  62  62  PRO PRO B . n 
B 1 63  VAL 63  63  63  VAL VAL B . n 
B 1 64  GLY 64  64  64  GLY GLY B . n 
B 1 65  ARG 65  65  65  ARG ARG B . n 
B 1 66  VAL 66  66  66  VAL VAL B . n 
B 1 67  LEU 67  67  67  LEU LEU B . n 
B 1 68  PRO 68  68  68  PRO PRO B . n 
B 1 69  ALA 69  69  69  ALA ALA B . n 
B 1 70  GLU 70  70  70  GLU GLU B . n 
B 1 71  VAL 71  71  71  VAL VAL B . n 
B 1 72  LEU 72  72  72  LEU LEU B . n 
B 1 73  ALA 73  73  73  ALA ALA B . n 
B 1 74  GLN 74  74  74  GLN GLN B . n 
B 1 75  TRP 75  75  75  TRP TRP B . n 
B 1 76  GLU 76  76  76  GLU GLU B . n 
B 1 77  PRO 77  77  77  PRO PRO B . n 
B 1 78  LEU 78  78  78  LEU LEU B . n 
B 1 79  VAL 79  79  79  VAL VAL B . n 
B 1 80  ALA 80  80  80  ALA ALA B . n 
B 1 81  ARG 81  81  81  ARG ARG B . n 
B 1 82  GLY 82  82  82  GLY GLY B . n 
B 1 83  SER 83  83  83  SER SER B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  ARG 85  85  85  ARG ARG B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  VAL 87  87  87  VAL VAL B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  ALA 92  92  92  ALA ALA B . n 
B 1 93  TYR 93  93  93  TYR TYR B . n 
B 1 94  ARG 94  94  94  ARG ARG B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  LEU 97  97  97  LEU LEU B . n 
B 1 98  HIS 98  98  98  HIS HIS B . n 
B 1 99  GLU 99  99  99  GLU GLU B . n 
B 1 100 SER 100 100 100 SER SER B . n 
B 1 101 ASP 101 101 101 ASP ASP B . n 
B 1 102 GLY 102 102 102 GLY GLY B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 THR 104 104 104 THR THR B . n 
B 1 105 VAL 105 105 105 VAL VAL B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 GLU 107 107 107 GLU GLU B . n 
B 1 108 LEU 108 108 108 LEU LEU B . n 
B 1 109 GLU 109 109 109 GLU GLU B . n 
B 1 110 PRO 110 110 110 PRO PRO B . n 
B 1 111 ALA 111 111 111 ALA ALA B . n 
B 1 112 GLU 112 112 112 GLU GLU B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 GLN 114 114 114 GLN GLN B . n 
B 1 115 PRO 115 115 115 PRO PRO B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 MET 117 117 117 MET MET B . n 
B 1 118 GLU 118 118 118 GLU GLU B . n 
B 1 119 GLU 119 119 119 GLU GLU B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 ALA 121 121 121 ALA ALA B . n 
B 1 122 LEU 122 122 122 LEU LEU B . n 
B 1 123 GLU 123 123 123 GLU GLU B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 ARG 126 126 126 ARG ARG B . n 
B 1 127 ARG 127 127 127 ARG ARG B . n 
B 1 128 LEU 128 128 128 LEU LEU B . n 
B 1 129 VAL 129 129 129 VAL VAL B . n 
B 1 130 SER 130 130 130 SER SER B . n 
B 1 131 PRO 131 131 131 PRO PRO B . n 
B 1 132 LEU 132 132 132 LEU LEU B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 GLY 134 134 134 GLY GLY B . n 
B 1 135 VAL 135 135 135 VAL VAL B . n 
B 1 136 LYS 136 136 136 LYS LYS B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 THR 138 138 138 THR THR B . n 
B 1 139 GLN 139 139 139 GLN GLN B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 LEU 141 141 141 LEU LEU B . n 
B 1 142 LEU 142 142 142 LEU LEU B . n 
B 1 143 GLN 143 143 143 GLN GLN B . n 
B 1 144 THR 144 144 144 THR THR B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 ALA 146 146 146 ALA ALA B . n 
B 1 147 ASP 147 147 147 ASP ASP B . n 
B 1 148 THR 148 148 148 THR THR B . n 
B 1 149 VAL 149 149 149 VAL VAL B . n 
B 1 150 ARG 150 150 150 ARG ARG B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 LEU 152 152 152 LEU LEU B . n 
B 1 153 THR 153 153 153 THR THR B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 PHE 155 155 155 PHE PHE B . n 
B 1 156 ASP 156 156 156 ASP ASP B . n 
B 1 157 ARG 157 157 157 ARG ARG B . n 
B 1 158 VAL 158 158 158 VAL VAL B . n 
B 1 159 MET 159 159 159 MET MET B . n 
B 1 160 VAL 160 160 160 VAL VAL B . n 
B 1 161 TYR 161 161 161 TYR TYR B . n 
B 1 162 ARG 162 162 162 ARG ARG B . n 
B 1 163 PHE 163 163 163 PHE PHE B . n 
B 1 164 ASP 164 164 164 ASP ASP B . n 
B 1 165 ALA 165 165 165 ALA ALA B . n 
B 1 166 ASP 166 166 166 ASP ASP B . n 
B 1 167 TRP 167 167 167 TRP TRP B . n 
B 1 168 HIS 168 168 168 HIS HIS B . n 
B 1 169 GLY 169 169 169 GLY GLY B . n 
B 1 170 GLU 170 170 170 GLU GLU B . n 
B 1 171 VAL 171 171 171 VAL VAL B . n 
B 1 172 LEU 172 172 172 LEU LEU B . n 
B 1 173 ALA 173 173 173 ALA ALA B . n 
B 1 174 GLU 174 174 174 GLU GLU B . n 
B 1 175 SER 175 175 175 SER SER B . n 
B 1 176 LYS 176 176 176 LYS LYS B . n 
B 1 177 ARG 177 177 177 ARG ARG B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 GLY 179 179 179 GLY GLY B . n 
B 1 180 MET 180 180 180 MET MET B . n 
B 1 181 ASP 181 181 181 ASP ASP B . n 
B 1 182 GLY 182 182 182 GLY GLY B . n 
B 1 183 PHE 183 183 183 PHE PHE B . n 
B 1 184 LEU 184 184 184 LEU LEU B . n 
B 1 185 GLY 185 185 185 GLY GLY B . n 
B 1 186 MET 186 186 186 MET MET B . n 
B 1 187 HIS 187 187 187 HIS HIS B . n 
B 1 188 PHE 188 188 188 PHE PHE B . n 
B 1 189 PRO 189 189 189 PRO PRO B . n 
B 1 190 ALA 190 190 190 ALA ALA B . n 
B 1 191 THR 191 191 191 THR THR B . n 
B 1 192 ASP 192 192 192 ASP ASP B . n 
B 1 193 ILE 193 193 193 ILE ILE B . n 
B 1 194 PRO 194 194 194 PRO PRO B . n 
B 1 195 VAL 195 195 195 VAL VAL B . n 
B 1 196 GLN 196 196 196 GLN GLN B . n 
B 1 197 ALA 197 197 197 ALA ALA B . n 
B 1 198 ARG 198 198 198 ARG ARG B . n 
B 1 199 ALA 199 199 199 ALA ALA B . n 
B 1 200 LEU 200 200 200 LEU LEU B . n 
B 1 201 TYR 201 201 201 TYR TYR B . n 
B 1 202 THR 202 202 202 THR THR B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 ASN 204 204 204 ASN ASN B . n 
B 1 205 PRO 205 205 205 PRO PRO B . n 
B 1 206 LEU 206 206 206 LEU LEU B . n 
B 1 207 ARG 207 207 207 ARG ARG B . n 
B 1 208 LEU 208 208 208 LEU LEU B . n 
B 1 209 ILE 209 209 209 ILE ILE B . n 
B 1 210 ALA 210 210 210 ALA ALA B . n 
B 1 211 ASP 211 211 211 ASP ASP B . n 
B 1 212 ALA 212 212 212 ALA ALA B . n 
B 1 213 ARG 213 213 213 ARG ARG B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 ARG 215 215 215 ARG ARG B . n 
B 1 216 PRO 216 216 216 PRO PRO B . n 
B 1 217 VAL 217 217 217 VAL VAL B . n 
B 1 218 PRO 218 218 218 PRO PRO B . n 
B 1 219 LEU 219 219 219 LEU LEU B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 PRO 221 221 221 PRO PRO B . n 
B 1 222 PRO 222 222 222 PRO PRO B . n 
B 1 223 VAL 223 223 223 VAL VAL B . n 
B 1 224 VAL 224 224 224 VAL VAL B . n 
B 1 225 PRO 225 225 225 PRO PRO B . n 
B 1 226 ALA 226 226 226 ALA ALA B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 GLY 228 228 228 GLY GLY B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 PRO 230 230 230 PRO PRO B . n 
B 1 231 LEU 231 231 231 LEU LEU B . n 
B 1 232 ASP 232 232 232 ASP ASP B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 SER 234 234 234 SER SER B . n 
B 1 235 ASN 235 235 235 ASN ASN B . n 
B 1 236 SER 236 236 236 SER SER B . n 
B 1 237 ALA 237 237 237 ALA ALA B . n 
B 1 238 LEU 238 238 238 LEU LEU B . n 
B 1 239 ARG 239 239 239 ARG ARG B . n 
B 1 240 SER 240 240 240 SER SER B . n 
B 1 241 VAL 241 241 241 VAL VAL B . n 
B 1 242 SER 242 242 242 SER SER B . n 
B 1 243 PRO 243 243 243 PRO PRO B . n 
B 1 244 VAL 244 244 244 VAL VAL B . n 
B 1 245 HIS 245 245 245 HIS HIS B . n 
B 1 246 LEU 246 246 246 LEU LEU B . n 
B 1 247 GLU 247 247 247 GLU GLU B . n 
B 1 248 TYR 248 248 248 TYR TYR B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 ARG 250 250 250 ARG ARG B . n 
B 1 251 ASN 251 251 251 ASN ASN B . n 
B 1 252 MET 252 252 252 MET MET B . n 
B 1 253 GLY 253 253 253 GLY GLY B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 GLY 255 255 255 GLY GLY B . n 
B 1 256 ALA 256 256 256 ALA ALA B . n 
B 1 257 SER 257 257 257 SER SER B . n 
B 1 258 PHE 258 258 258 PHE PHE B . n 
B 1 259 SER 259 259 259 SER SER B . n 
B 1 260 LEU 260 260 260 LEU LEU B . n 
B 1 261 SER 261 261 261 SER SER B . n 
B 1 262 LEU 262 262 262 LEU LEU B . n 
B 1 263 LEU 263 263 263 LEU LEU B . n 
B 1 264 LYS 264 264 264 LYS LYS B . n 
B 1 265 GLU 265 265 265 GLU GLU B . n 
B 1 266 GLY 266 266 266 GLY GLY B . n 
B 1 267 VAL 267 267 267 VAL VAL B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 TRP 269 269 269 TRP TRP B . n 
B 1 270 GLY 270 270 270 GLY GLY B . n 
B 1 271 LEU 271 271 271 LEU LEU B . n 
B 1 272 ILE 272 272 272 ILE ILE B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 CYS 274 274 274 CYS CYS B . n 
B 1 275 HIS 275 275 275 HIS HIS B . n 
B 1 276 HIS 276 276 276 HIS HIS B . n 
B 1 277 LEU 277 277 277 LEU LEU B . n 
B 1 278 GLU 278 278 278 GLU GLU B . n 
B 1 279 PRO 279 279 279 PRO PRO B . n 
B 1 280 LEU 280 280 280 LEU LEU B . n 
B 1 281 HIS 281 281 281 HIS HIS B . n 
B 1 282 ILE 282 282 282 ILE ILE B . n 
B 1 283 SER 283 283 283 SER SER B . n 
B 1 284 HIS 284 284 284 HIS HIS B . n 
B 1 285 GLU 285 285 285 GLU GLU B . n 
B 1 286 ARG 286 286 286 ARG ARG B . n 
B 1 287 ARG 287 287 287 ARG ARG B . n 
B 1 288 ARG 288 288 288 ARG ARG B . n 
B 1 289 ALA 289 289 289 ALA ALA B . n 
B 1 290 CYS 290 290 290 CYS CYS B . n 
B 1 291 GLU 291 291 291 GLU GLU B . n 
B 1 292 VAL 292 292 292 VAL VAL B . n 
B 1 293 LEU 293 293 293 LEU LEU B . n 
B 1 294 THR 294 294 294 THR THR B . n 
B 1 295 GLN 295 295 295 GLN GLN B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 LEU 297 297 297 LEU LEU B . n 
B 1 298 ALA 298 298 298 ALA ALA B . n 
B 1 299 LEU 299 299 299 LEU LEU B . n 
B 1 300 GLN 300 300 300 GLN GLN B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 SER 302 302 302 SER SER B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 GLU 304 304 304 GLU GLU B . n 
B 1 305 GLU 305 305 305 GLU GLU B . n 
B 1 306 ARG 306 306 306 ARG ARG B . n 
B 1 307 ALA 307 307 307 ALA ALA B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 GLU 309 309 309 GLU GLU B . n 
B 1 310 ALA 310 310 310 ALA ALA B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 GLU 312 312 312 GLU GLU B . n 
B 1 313 ASP 313 313 313 ASP ASP B . n 
B 1 314 ALA 314 314 314 ALA ALA B . n 
B 1 315 HIS 315 315 315 HIS HIS B . n 
B 1 316 ARG 316 316 316 ARG ARG B . n 
B 1 317 ALA 317 317 317 ALA ALA B . n 
B 1 318 ALA 318 318 318 ALA ALA B . n 
B 1 319 LEU 319 319 319 LEU LEU B . n 
B 1 320 LEU 320 320 320 LEU LEU B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 GLN 322 322 322 GLN GLN B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 ALA 324 324 324 ALA ALA B . n 
B 1 325 THR 325 325 325 THR THR B . n 
B 1 326 ALA 326 326 326 ALA ALA B . n 
B 1 327 MET 327 327 327 MET MET B . n 
B 1 328 GLY 328 328 328 GLY GLY B . n 
B 1 329 GLU 329 329 329 GLU GLU B . n 
B 1 330 GLY 330 330 330 GLY GLY B . n 
B 1 331 GLY 331 331 331 GLY GLY B . n 
B 1 332 THR 332 332 332 THR ALA B . n 
B 1 333 LEU 333 333 333 LEU LEU B . n 
B 1 334 GLU 334 334 334 GLU GLU B . n 
B 1 335 GLU 335 335 335 GLU GLU B . n 
B 1 336 VAL 336 336 336 VAL VAL B . n 
B 1 337 LEU 337 337 337 LEU LEU B . n 
B 1 338 GLU 338 338 338 GLU GLU B . n 
B 1 339 LYS 339 339 339 LYS LYS B . n 
B 1 340 GLU 340 340 340 GLU GLU B . n 
B 1 341 SER 341 341 341 SER SER B . n 
B 1 342 GLU 342 342 342 GLU GLU B . n 
B 1 343 ARG 343 343 343 ARG ARG B . n 
B 1 344 VAL 344 344 344 VAL VAL B . n 
B 1 345 LEU 345 345 345 LEU LEU B . n 
B 1 346 ALA 346 346 346 ALA ALA B . n 
B 1 347 LEU 347 347 347 LEU LEU B . n 
B 1 348 THR 348 348 348 THR THR B . n 
B 1 349 GLY 349 349 349 GLY GLY B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 ALA 351 351 351 ALA ALA B . n 
B 1 352 GLY 352 352 352 GLY GLY B . n 
B 1 353 VAL 353 353 353 VAL VAL B . n 
B 1 354 ALA 354 354 354 ALA ALA B . n 
B 1 355 LEU 355 355 355 LEU LEU B . n 
B 1 356 LEU 356 356 356 LEU LEU B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 GLY 358 358 358 GLY GLY B . n 
B 1 359 GLU 359 359 359 GLU GLU B . n 
B 1 360 GLU 360 360 360 GLU GLU B . n 
B 1 361 PRO 361 361 361 PRO PRO B . n 
B 1 362 LEU 362 362 362 LEU LEU B . n 
B 1 363 LEU 363 363 363 LEU LEU B . n 
B 1 364 VAL 364 364 364 VAL VAL B . n 
B 1 365 GLY 365 365 365 GLY GLY B . n 
B 1 366 CYS 366 366 366 CYS CYS B . n 
B 1 367 THR 367 367 367 THR THR B . n 
B 1 368 PRO 368 368 368 PRO PRO B . n 
B 1 369 ALA 369 369 369 ALA ALA B . n 
B 1 370 GLN 370 370 370 GLN GLN B . n 
B 1 371 ASP 371 371 371 ASP ASP B . n 
B 1 372 GLU 372 372 372 GLU GLU B . n 
B 1 373 VAL 373 373 373 VAL VAL B . n 
B 1 374 GLU 374 374 374 GLU GLU B . n 
B 1 375 ALA 375 375 375 ALA ALA B . n 
B 1 376 LEU 376 376 376 LEU LEU B . n 
B 1 377 VAL 377 377 377 VAL VAL B . n 
B 1 378 ALA 378 378 378 ALA ALA B . n 
B 1 379 TRP 379 379 379 TRP TRP B . n 
B 1 380 LEU 380 380 380 LEU LEU B . n 
B 1 381 ALA 381 381 381 ALA ALA B . n 
B 1 382 THR 382 382 382 THR THR B . n 
B 1 383 GLN 383 383 383 GLN GLN B . n 
B 1 384 PRO 384 384 384 PRO PRO B . n 
B 1 385 PHE 385 385 385 PHE PHE B . n 
B 1 386 GLN 386 386 386 GLN GLN B . n 
B 1 387 THR 387 387 387 THR THR B . n 
B 1 388 SER 388 388 388 SER SER B . n 
B 1 389 PHE 389 389 389 PHE PHE B . n 
B 1 390 HIS 390 390 390 HIS HIS B . n 
B 1 391 THR 391 391 391 THR THR B . n 
B 1 392 ASP 392 392 392 ASP ASP B . n 
B 1 393 ARG 393 393 393 ARG ARG B . n 
B 1 394 LEU 394 394 394 LEU LEU B . n 
B 1 395 GLY 395 395 395 GLY GLY B . n 
B 1 396 THR 396 396 396 THR THR B . n 
B 1 397 VAL 397 397 397 VAL VAL B . n 
B 1 398 TYR 398 398 398 TYR TYR B . n 
B 1 399 PRO 399 399 399 PRO PRO B . n 
B 1 400 PRO 400 400 400 PRO PRO B . n 
B 1 401 LEU 401 401 401 LEU LEU B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 ALA 403 403 403 ALA ALA B . n 
B 1 404 ARG 404 404 404 ARG ARG B . n 
B 1 405 ALA 405 405 405 ALA ALA B . n 
B 1 406 ASP 406 406 406 ASP ASP B . n 
B 1 407 VAL 407 407 407 VAL VAL B . n 
B 1 408 ALA 408 408 408 ALA ALA B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 GLY 410 410 410 GLY GLY B . n 
B 1 411 ILE 411 411 411 ILE ILE B . n 
B 1 412 LEU 412 412 412 LEU LEU B . n 
B 1 413 ALA 413 413 413 ALA ALA B . n 
B 1 414 VAL 414 414 414 VAL VAL B . n 
B 1 415 ARG 415 415 415 ARG ARG B . n 
B 1 416 LEU 416 416 416 LEU LEU B . n 
B 1 417 ALA 417 417 417 ALA ALA B . n 
B 1 418 PRO 418 418 418 PRO PRO B . n 
B 1 419 ALA 419 419 419 ALA ALA B . n 
B 1 420 ALA 420 420 420 ALA ALA B . n 
B 1 421 ALA 421 421 421 ALA ALA B . n 
B 1 422 ARG 422 422 422 ARG ARG B . n 
B 1 423 PHE 423 423 423 PHE PHE B . n 
B 1 424 ALA 424 424 424 ALA ALA B . n 
B 1 425 ILE 425 425 425 ILE ILE B . n 
B 1 426 TRP 426 426 426 TRP TRP B . n 
B 1 427 PHE 427 427 427 PHE PHE B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 PRO 429 429 429 PRO PRO B . n 
B 1 430 GLU 430 430 430 GLU GLU B . n 
B 1 431 VAL 431 431 431 VAL VAL B . n 
B 1 432 ALA 432 432 432 ALA ALA B . n 
B 1 433 ARG 433 433 433 ARG ARG B . n 
B 1 434 THR 434 434 434 THR THR B . n 
B 1 435 ILE 435 435 435 ILE ILE B . n 
B 1 436 SER 436 436 436 SER SER B . n 
B 1 437 TRP 437 437 437 TRP TRP B . n 
B 1 438 ALA 438 438 438 ALA ALA B . n 
B 1 439 GLY 439 439 439 GLY GLY B . n 
B 1 440 ASN 440 440 440 ASN ASN B . n 
B 1 441 PRO 441 441 441 PRO PRO B . n 
B 1 442 ARG 442 442 442 ARG ARG B . n 
B 1 443 LYS 443 443 443 LYS LYS B . n 
B 1 444 PRO 444 444 444 PRO PRO B . n 
B 1 445 ALA 445 445 445 ALA ALA B . n 
B 1 446 GLU 446 446 446 GLU GLU B . n 
B 1 447 PRO 447 447 447 PRO PRO B . n 
B 1 448 GLU 448 448 448 GLU GLU B . n 
B 1 449 PRO 449 449 449 PRO PRO B . n 
B 1 450 GLY 450 450 450 GLY GLY B . n 
B 1 451 HIS 451 451 451 HIS HIS B . n 
B 1 452 GLN 452 452 452 GLN GLN B . n 
B 1 453 ARG 453 453 453 ARG ARG B . n 
B 1 454 LEU 454 454 454 LEU LEU B . n 
B 1 455 HIS 455 455 455 HIS HIS B . n 
B 1 456 PRO 456 456 456 PRO PRO B . n 
B 1 457 ARG 457 457 457 ARG ARG B . n 
B 1 458 GLY 458 458 458 GLY GLY B . n 
B 1 459 SER 459 459 459 SER SER B . n 
B 1 460 PHE 460 460 460 PHE PHE B . n 
B 1 461 GLN 461 461 461 GLN GLN B . n 
B 1 462 ALA 462 462 462 ALA ALA B . n 
B 1 463 TRP 463 463 463 TRP TRP B . n 
B 1 464 GLU 464 464 464 GLU GLU B . n 
B 1 465 GLU 465 465 465 GLU GLU B . n 
B 1 466 THR 466 466 466 THR THR B . n 
B 1 467 VAL 467 467 467 VAL VAL B . n 
B 1 468 ARG 468 468 468 ARG ARG B . n 
B 1 469 ASP 469 469 469 ASP ASP B . n 
B 1 470 THR 470 470 470 THR THR B . n 
B 1 471 SER 471 471 471 SER SER B . n 
B 1 472 LEU 472 472 472 LEU LEU B . n 
B 1 473 PRO 473 473 473 PRO PRO B . n 
B 1 474 TRP 474 474 474 TRP TRP B . n 
B 1 475 LYS 475 475 475 LYS LYS B . n 
B 1 476 ARG 476 476 476 ARG ARG B . n 
B 1 477 ALA 477 477 477 ALA ALA B . n 
B 1 478 ASP 478 478 478 ASP ASP B . n 
B 1 479 LEU 479 479 479 LEU LEU B . n 
B 1 480 GLY 480 480 480 GLY GLY B . n 
B 1 481 ALA 481 481 481 ALA ALA B . n 
B 1 482 ALA 482 482 482 ALA ALA B . n 
B 1 483 GLU 483 483 483 GLU GLU B . n 
B 1 484 GLY 484 484 484 GLY GLY B . n 
B 1 485 PHE 485 485 485 PHE PHE B . n 
B 1 486 ARG 486 486 486 ARG ARG B . n 
B 1 487 GLY 487 487 487 GLY GLY B . n 
B 1 488 ALA 488 488 488 ALA ALA B . n 
B 1 489 LEU 489 489 489 LEU LEU B . n 
B 1 490 VAL 490 490 490 VAL VAL B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 BLA 1   501 522 BLA BLA A . 
D 3 BEN 1   502 601 BEN BEN A . 
E 2 BLA 1   501 522 BLA BLA B . 
F 4 HOH 1   601 23  HOH HOH A . 
F 4 HOH 2   602 299 HOH HOH A . 
F 4 HOH 3   603 373 HOH HOH A . 
F 4 HOH 4   604 317 HOH HOH A . 
F 4 HOH 5   605 183 HOH HOH A . 
F 4 HOH 6   606 241 HOH HOH A . 
F 4 HOH 7   607 211 HOH HOH A . 
F 4 HOH 8   608 273 HOH HOH A . 
F 4 HOH 9   609 166 HOH HOH A . 
F 4 HOH 10  610 70  HOH HOH A . 
F 4 HOH 11  611 5   HOH HOH A . 
F 4 HOH 12  612 43  HOH HOH A . 
F 4 HOH 13  613 244 HOH HOH A . 
F 4 HOH 14  614 45  HOH HOH A . 
F 4 HOH 15  615 106 HOH HOH A . 
F 4 HOH 16  616 75  HOH HOH A . 
F 4 HOH 17  617 19  HOH HOH A . 
F 4 HOH 18  618 232 HOH HOH A . 
F 4 HOH 19  619 236 HOH HOH A . 
F 4 HOH 20  620 228 HOH HOH A . 
F 4 HOH 21  621 275 HOH HOH A . 
F 4 HOH 22  622 101 HOH HOH A . 
F 4 HOH 23  623 368 HOH HOH A . 
F 4 HOH 24  624 200 HOH HOH A . 
F 4 HOH 25  625 107 HOH HOH A . 
F 4 HOH 26  626 137 HOH HOH A . 
F 4 HOH 27  627 46  HOH HOH A . 
F 4 HOH 28  628 191 HOH HOH A . 
F 4 HOH 29  629 142 HOH HOH A . 
F 4 HOH 30  630 63  HOH HOH A . 
F 4 HOH 31  631 376 HOH HOH A . 
F 4 HOH 32  632 111 HOH HOH A . 
F 4 HOH 33  633 306 HOH HOH A . 
F 4 HOH 34  634 25  HOH HOH A . 
F 4 HOH 35  635 42  HOH HOH A . 
F 4 HOH 36  636 169 HOH HOH A . 
F 4 HOH 37  637 165 HOH HOH A . 
F 4 HOH 38  638 27  HOH HOH A . 
F 4 HOH 39  639 130 HOH HOH A . 
F 4 HOH 40  640 13  HOH HOH A . 
F 4 HOH 41  641 7   HOH HOH A . 
F 4 HOH 42  642 85  HOH HOH A . 
F 4 HOH 43  643 113 HOH HOH A . 
F 4 HOH 44  644 76  HOH HOH A . 
F 4 HOH 45  645 1   HOH HOH A . 
F 4 HOH 46  646 79  HOH HOH A . 
F 4 HOH 47  647 335 HOH HOH A . 
F 4 HOH 48  648 20  HOH HOH A . 
F 4 HOH 49  649 17  HOH HOH A . 
F 4 HOH 50  650 146 HOH HOH A . 
F 4 HOH 51  651 21  HOH HOH A . 
F 4 HOH 52  652 28  HOH HOH A . 
F 4 HOH 53  653 64  HOH HOH A . 
F 4 HOH 54  654 237 HOH HOH A . 
F 4 HOH 55  655 377 HOH HOH A . 
F 4 HOH 56  656 251 HOH HOH A . 
F 4 HOH 57  657 6   HOH HOH A . 
F 4 HOH 58  658 213 HOH HOH A . 
F 4 HOH 59  659 29  HOH HOH A . 
F 4 HOH 60  660 74  HOH HOH A . 
F 4 HOH 61  661 221 HOH HOH A . 
F 4 HOH 62  662 148 HOH HOH A . 
F 4 HOH 63  663 147 HOH HOH A . 
F 4 HOH 64  664 83  HOH HOH A . 
F 4 HOH 65  665 354 HOH HOH A . 
F 4 HOH 66  666 131 HOH HOH A . 
F 4 HOH 67  667 324 HOH HOH A . 
F 4 HOH 68  668 65  HOH HOH A . 
F 4 HOH 69  669 149 HOH HOH A . 
F 4 HOH 70  670 372 HOH HOH A . 
F 4 HOH 71  671 10  HOH HOH A . 
F 4 HOH 72  672 366 HOH HOH A . 
F 4 HOH 73  673 189 HOH HOH A . 
F 4 HOH 74  674 32  HOH HOH A . 
F 4 HOH 75  675 132 HOH HOH A . 
F 4 HOH 76  676 193 HOH HOH A . 
F 4 HOH 77  677 44  HOH HOH A . 
F 4 HOH 78  678 249 HOH HOH A . 
F 4 HOH 79  679 305 HOH HOH A . 
F 4 HOH 80  680 339 HOH HOH A . 
F 4 HOH 81  681 153 HOH HOH A . 
F 4 HOH 82  682 136 HOH HOH A . 
F 4 HOH 83  683 380 HOH HOH A . 
F 4 HOH 84  684 256 HOH HOH A . 
F 4 HOH 85  685 22  HOH HOH A . 
F 4 HOH 86  686 95  HOH HOH A . 
F 4 HOH 87  687 89  HOH HOH A . 
F 4 HOH 88  688 276 HOH HOH A . 
F 4 HOH 89  689 269 HOH HOH A . 
F 4 HOH 90  690 18  HOH HOH A . 
F 4 HOH 91  691 97  HOH HOH A . 
F 4 HOH 92  692 161 HOH HOH A . 
F 4 HOH 93  693 283 HOH HOH A . 
F 4 HOH 94  694 224 HOH HOH A . 
F 4 HOH 95  695 92  HOH HOH A . 
F 4 HOH 96  696 116 HOH HOH A . 
F 4 HOH 97  697 316 HOH HOH A . 
F 4 HOH 98  698 379 HOH HOH A . 
F 4 HOH 99  699 342 HOH HOH A . 
F 4 HOH 100 700 309 HOH HOH A . 
F 4 HOH 101 701 155 HOH HOH A . 
F 4 HOH 102 702 257 HOH HOH A . 
F 4 HOH 103 703 90  HOH HOH A . 
F 4 HOH 104 704 82  HOH HOH A . 
F 4 HOH 105 705 67  HOH HOH A . 
F 4 HOH 106 706 208 HOH HOH A . 
F 4 HOH 107 707 291 HOH HOH A . 
F 4 HOH 108 708 171 HOH HOH A . 
F 4 HOH 109 709 365 HOH HOH A . 
F 4 HOH 110 710 253 HOH HOH A . 
F 4 HOH 111 711 26  HOH HOH A . 
F 4 HOH 112 712 351 HOH HOH A . 
F 4 HOH 113 713 139 HOH HOH A . 
F 4 HOH 114 714 207 HOH HOH A . 
F 4 HOH 115 715 73  HOH HOH A . 
F 4 HOH 116 716 353 HOH HOH A . 
F 4 HOH 117 717 312 HOH HOH A . 
F 4 HOH 118 718 170 HOH HOH A . 
F 4 HOH 119 719 14  HOH HOH A . 
F 4 HOH 120 720 158 HOH HOH A . 
F 4 HOH 121 721 188 HOH HOH A . 
F 4 HOH 122 722 124 HOH HOH A . 
F 4 HOH 123 723 138 HOH HOH A . 
F 4 HOH 124 724 58  HOH HOH A . 
F 4 HOH 125 725 162 HOH HOH A . 
F 4 HOH 126 726 100 HOH HOH A . 
F 4 HOH 127 727 375 HOH HOH A . 
F 4 HOH 128 728 84  HOH HOH A . 
F 4 HOH 129 729 318 HOH HOH A . 
F 4 HOH 130 730 308 HOH HOH A . 
F 4 HOH 131 731 66  HOH HOH A . 
F 4 HOH 132 732 218 HOH HOH A . 
F 4 HOH 133 733 280 HOH HOH A . 
F 4 HOH 134 734 114 HOH HOH A . 
F 4 HOH 135 735 108 HOH HOH A . 
F 4 HOH 136 736 190 HOH HOH A . 
F 4 HOH 137 737 302 HOH HOH A . 
F 4 HOH 138 738 262 HOH HOH A . 
F 4 HOH 139 739 267 HOH HOH A . 
F 4 HOH 140 740 361 HOH HOH A . 
F 4 HOH 141 741 199 HOH HOH A . 
F 4 HOH 142 742 68  HOH HOH A . 
F 4 HOH 143 743 227 HOH HOH A . 
F 4 HOH 144 744 128 HOH HOH A . 
F 4 HOH 145 745 195 HOH HOH A . 
F 4 HOH 146 746 271 HOH HOH A . 
F 4 HOH 147 747 334 HOH HOH A . 
F 4 HOH 148 748 234 HOH HOH A . 
F 4 HOH 149 749 261 HOH HOH A . 
F 4 HOH 150 750 30  HOH HOH A . 
F 4 HOH 151 751 311 HOH HOH A . 
F 4 HOH 152 752 315 HOH HOH A . 
F 4 HOH 153 753 350 HOH HOH A . 
F 4 HOH 154 754 121 HOH HOH A . 
F 4 HOH 155 755 212 HOH HOH A . 
F 4 HOH 156 756 287 HOH HOH A . 
F 4 HOH 157 757 182 HOH HOH A . 
F 4 HOH 158 758 349 HOH HOH A . 
F 4 HOH 159 759 71  HOH HOH A . 
F 4 HOH 160 760 194 HOH HOH A . 
F 4 HOH 161 761 238 HOH HOH A . 
F 4 HOH 162 762 240 HOH HOH A . 
F 4 HOH 163 763 333 HOH HOH A . 
F 4 HOH 164 764 248 HOH HOH A . 
F 4 HOH 165 765 382 HOH HOH A . 
F 4 HOH 166 766 235 HOH HOH A . 
F 4 HOH 167 767 206 HOH HOH A . 
F 4 HOH 168 768 362 HOH HOH A . 
F 4 HOH 169 769 356 HOH HOH A . 
F 4 HOH 170 770 294 HOH HOH A . 
F 4 HOH 171 771 336 HOH HOH A . 
F 4 HOH 172 772 281 HOH HOH A . 
F 4 HOH 173 773 120 HOH HOH A . 
F 4 HOH 174 774 192 HOH HOH A . 
F 4 HOH 175 775 313 HOH HOH A . 
F 4 HOH 176 776 245 HOH HOH A . 
F 4 HOH 177 777 239 HOH HOH A . 
F 4 HOH 178 778 204 HOH HOH A . 
F 4 HOH 179 779 86  HOH HOH A . 
F 4 HOH 180 780 201 HOH HOH A . 
F 4 HOH 181 781 369 HOH HOH A . 
F 4 HOH 182 782 320 HOH HOH A . 
F 4 HOH 183 783 233 HOH HOH A . 
F 4 HOH 184 784 292 HOH HOH A . 
G 4 HOH 1   601 144 HOH HOH B . 
G 4 HOH 2   602 56  HOH HOH B . 
G 4 HOH 3   603 352 HOH HOH B . 
G 4 HOH 4   604 156 HOH HOH B . 
G 4 HOH 5   605 36  HOH HOH B . 
G 4 HOH 6   606 325 HOH HOH B . 
G 4 HOH 7   607 93  HOH HOH B . 
G 4 HOH 8   608 178 HOH HOH B . 
G 4 HOH 9   609 179 HOH HOH B . 
G 4 HOH 10  610 103 HOH HOH B . 
G 4 HOH 11  611 260 HOH HOH B . 
G 4 HOH 12  612 94  HOH HOH B . 
G 4 HOH 13  613 38  HOH HOH B . 
G 4 HOH 14  614 41  HOH HOH B . 
G 4 HOH 15  615 37  HOH HOH B . 
G 4 HOH 16  616 39  HOH HOH B . 
G 4 HOH 17  617 203 HOH HOH B . 
G 4 HOH 18  618 80  HOH HOH B . 
G 4 HOH 19  619 50  HOH HOH B . 
G 4 HOH 20  620 263 HOH HOH B . 
G 4 HOH 21  621 117 HOH HOH B . 
G 4 HOH 22  622 2   HOH HOH B . 
G 4 HOH 23  623 279 HOH HOH B . 
G 4 HOH 24  624 140 HOH HOH B . 
G 4 HOH 25  625 152 HOH HOH B . 
G 4 HOH 26  626 4   HOH HOH B . 
G 4 HOH 27  627 160 HOH HOH B . 
G 4 HOH 28  628 265 HOH HOH B . 
G 4 HOH 29  629 184 HOH HOH B . 
G 4 HOH 30  630 122 HOH HOH B . 
G 4 HOH 31  631 319 HOH HOH B . 
G 4 HOH 32  632 15  HOH HOH B . 
G 4 HOH 33  633 223 HOH HOH B . 
G 4 HOH 34  634 383 HOH HOH B . 
G 4 HOH 35  635 8   HOH HOH B . 
G 4 HOH 36  636 264 HOH HOH B . 
G 4 HOH 37  637 173 HOH HOH B . 
G 4 HOH 38  638 47  HOH HOH B . 
G 4 HOH 39  639 61  HOH HOH B . 
G 4 HOH 40  640 57  HOH HOH B . 
G 4 HOH 41  641 247 HOH HOH B . 
G 4 HOH 42  642 72  HOH HOH B . 
G 4 HOH 43  643 16  HOH HOH B . 
G 4 HOH 44  644 215 HOH HOH B . 
G 4 HOH 45  645 3   HOH HOH B . 
G 4 HOH 46  646 198 HOH HOH B . 
G 4 HOH 47  647 164 HOH HOH B . 
G 4 HOH 48  648 185 HOH HOH B . 
G 4 HOH 49  649 374 HOH HOH B . 
G 4 HOH 50  650 125 HOH HOH B . 
G 4 HOH 51  651 367 HOH HOH B . 
G 4 HOH 52  652 186 HOH HOH B . 
G 4 HOH 53  653 205 HOH HOH B . 
G 4 HOH 54  654 52  HOH HOH B . 
G 4 HOH 55  655 88  HOH HOH B . 
G 4 HOH 56  656 219 HOH HOH B . 
G 4 HOH 57  657 12  HOH HOH B . 
G 4 HOH 58  658 109 HOH HOH B . 
G 4 HOH 59  659 282 HOH HOH B . 
G 4 HOH 60  660 33  HOH HOH B . 
G 4 HOH 61  661 370 HOH HOH B . 
G 4 HOH 62  662 59  HOH HOH B . 
G 4 HOH 63  663 266 HOH HOH B . 
G 4 HOH 64  664 328 HOH HOH B . 
G 4 HOH 65  665 303 HOH HOH B . 
G 4 HOH 66  666 9   HOH HOH B . 
G 4 HOH 67  667 24  HOH HOH B . 
G 4 HOH 68  668 53  HOH HOH B . 
G 4 HOH 69  669 323 HOH HOH B . 
G 4 HOH 70  670 48  HOH HOH B . 
G 4 HOH 71  671 277 HOH HOH B . 
G 4 HOH 72  672 181 HOH HOH B . 
G 4 HOH 73  673 258 HOH HOH B . 
G 4 HOH 74  674 99  HOH HOH B . 
G 4 HOH 75  675 272 HOH HOH B . 
G 4 HOH 76  676 105 HOH HOH B . 
G 4 HOH 77  677 119 HOH HOH B . 
G 4 HOH 78  678 91  HOH HOH B . 
G 4 HOH 79  679 295 HOH HOH B . 
G 4 HOH 80  680 40  HOH HOH B . 
G 4 HOH 81  681 301 HOH HOH B . 
G 4 HOH 82  682 34  HOH HOH B . 
G 4 HOH 83  683 371 HOH HOH B . 
G 4 HOH 84  684 364 HOH HOH B . 
G 4 HOH 85  685 98  HOH HOH B . 
G 4 HOH 86  686 110 HOH HOH B . 
G 4 HOH 87  687 286 HOH HOH B . 
G 4 HOH 88  688 135 HOH HOH B . 
G 4 HOH 89  689 154 HOH HOH B . 
G 4 HOH 90  690 175 HOH HOH B . 
G 4 HOH 91  691 81  HOH HOH B . 
G 4 HOH 92  692 87  HOH HOH B . 
G 4 HOH 93  693 226 HOH HOH B . 
G 4 HOH 94  694 327 HOH HOH B . 
G 4 HOH 95  695 11  HOH HOH B . 
G 4 HOH 96  696 268 HOH HOH B . 
G 4 HOH 97  697 78  HOH HOH B . 
G 4 HOH 98  698 31  HOH HOH B . 
G 4 HOH 99  699 174 HOH HOH B . 
G 4 HOH 100 700 49  HOH HOH B . 
G 4 HOH 101 701 54  HOH HOH B . 
G 4 HOH 102 702 229 HOH HOH B . 
G 4 HOH 103 703 180 HOH HOH B . 
G 4 HOH 104 704 69  HOH HOH B . 
G 4 HOH 105 705 250 HOH HOH B . 
G 4 HOH 106 706 346 HOH HOH B . 
G 4 HOH 107 707 96  HOH HOH B . 
G 4 HOH 108 708 278 HOH HOH B . 
G 4 HOH 109 709 307 HOH HOH B . 
G 4 HOH 110 710 358 HOH HOH B . 
G 4 HOH 111 711 348 HOH HOH B . 
G 4 HOH 112 712 123 HOH HOH B . 
G 4 HOH 113 713 337 HOH HOH B . 
G 4 HOH 114 714 243 HOH HOH B . 
G 4 HOH 115 715 143 HOH HOH B . 
G 4 HOH 116 716 126 HOH HOH B . 
G 4 HOH 117 717 378 HOH HOH B . 
G 4 HOH 118 718 141 HOH HOH B . 
G 4 HOH 119 719 359 HOH HOH B . 
G 4 HOH 120 720 225 HOH HOH B . 
G 4 HOH 121 721 332 HOH HOH B . 
G 4 HOH 122 722 77  HOH HOH B . 
G 4 HOH 123 723 102 HOH HOH B . 
G 4 HOH 124 724 115 HOH HOH B . 
G 4 HOH 125 725 151 HOH HOH B . 
G 4 HOH 126 726 214 HOH HOH B . 
G 4 HOH 127 727 216 HOH HOH B . 
G 4 HOH 128 728 220 HOH HOH B . 
G 4 HOH 129 729 129 HOH HOH B . 
G 4 HOH 130 730 321 HOH HOH B . 
G 4 HOH 131 731 51  HOH HOH B . 
G 4 HOH 132 732 285 HOH HOH B . 
G 4 HOH 133 733 168 HOH HOH B . 
G 4 HOH 134 734 304 HOH HOH B . 
G 4 HOH 135 735 230 HOH HOH B . 
G 4 HOH 136 736 344 HOH HOH B . 
G 4 HOH 137 737 112 HOH HOH B . 
G 4 HOH 138 738 209 HOH HOH B . 
G 4 HOH 139 739 202 HOH HOH B . 
G 4 HOH 140 740 177 HOH HOH B . 
G 4 HOH 141 741 345 HOH HOH B . 
G 4 HOH 142 742 150 HOH HOH B . 
G 4 HOH 143 743 217 HOH HOH B . 
G 4 HOH 144 744 357 HOH HOH B . 
G 4 HOH 145 745 222 HOH HOH B . 
G 4 HOH 146 746 343 HOH HOH B . 
G 4 HOH 147 747 284 HOH HOH B . 
G 4 HOH 148 748 197 HOH HOH B . 
G 4 HOH 149 749 133 HOH HOH B . 
G 4 HOH 150 750 159 HOH HOH B . 
G 4 HOH 151 751 231 HOH HOH B . 
G 4 HOH 152 752 163 HOH HOH B . 
G 4 HOH 153 753 347 HOH HOH B . 
G 4 HOH 154 754 326 HOH HOH B . 
G 4 HOH 155 755 338 HOH HOH B . 
G 4 HOH 156 756 297 HOH HOH B . 
G 4 HOH 157 757 331 HOH HOH B . 
G 4 HOH 158 758 145 HOH HOH B . 
G 4 HOH 159 759 363 HOH HOH B . 
G 4 HOH 160 760 172 HOH HOH B . 
G 4 HOH 161 761 242 HOH HOH B . 
G 4 HOH 162 762 360 HOH HOH B . 
G 4 HOH 163 763 381 HOH HOH B . 
G 4 HOH 164 764 127 HOH HOH B . 
G 4 HOH 165 765 60  HOH HOH B . 
G 4 HOH 166 766 252 HOH HOH B . 
G 4 HOH 167 767 341 HOH HOH B . 
G 4 HOH 168 768 104 HOH HOH B . 
G 4 HOH 169 769 296 HOH HOH B . 
G 4 HOH 170 770 290 HOH HOH B . 
G 4 HOH 171 771 259 HOH HOH B . 
G 4 HOH 172 772 210 HOH HOH B . 
G 4 HOH 173 773 246 HOH HOH B . 
G 4 HOH 174 774 196 HOH HOH B . 
G 4 HOH 175 775 35  HOH HOH B . 
G 4 HOH 176 776 329 HOH HOH B . 
G 4 HOH 177 777 55  HOH HOH B . 
G 4 HOH 178 778 118 HOH HOH B . 
G 4 HOH 179 779 330 HOH HOH B . 
G 4 HOH 180 780 176 HOH HOH B . 
G 4 HOH 181 781 355 HOH HOH B . 
G 4 HOH 182 782 322 HOH HOH B . 
G 4 HOH 183 783 300 HOH HOH B . 
G 4 HOH 184 784 274 HOH HOH B . 
G 4 HOH 185 785 167 HOH HOH B . 
G 4 HOH 186 786 298 HOH HOH B . 
G 4 HOH 187 787 62  HOH HOH B . 
G 4 HOH 188 788 270 HOH HOH B . 
G 4 HOH 189 789 340 HOH HOH B . 
G 4 HOH 190 790 288 HOH HOH B . 
G 4 HOH 191 791 289 HOH HOH B . 
G 4 HOH 192 792 293 HOH HOH B . 
G 4 HOH 193 793 255 HOH HOH B . 
G 4 HOH 194 794 310 HOH HOH B . 
G 4 HOH 195 795 157 HOH HOH B . 
G 4 HOH 196 796 254 HOH HOH B . 
G 4 HOH 197 797 314 HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B THR 332 ? OG1 ? B THR 332 OG1 
2 1 Y 1 B THR 332 ? CG2 ? B THR 332 CG2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.21_5207 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   107.630 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9D2H 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     83.690 
_cell.length_a_esd                 ? 
_cell.length_b                     83.400 
_cell.length_b_esd                 ? 
_cell.length_c                     86.870 
_cell.length_c_esd                 ? 
_cell.volume                       577852.534 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9D2H 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9D2H 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.73 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          55.03 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.6 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;0.085 M Na-citrate, 25.5 % PEG 4000, 15 % glycerol, 3% benzamidine hydrochloride, pH 5.6.
2:3 protein/precipitant ratio
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'PSI JUNGFRAU 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-02-12 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    multilayer 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.1 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID29' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.1 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID29 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          37.02 
_reflns.entry_id                                       9D2H 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.8 
_reflns.d_resolution_low                               119 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     50696 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                486 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   0.096 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.1 
_reflns_shell.d_res_low                                     2.15 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3314 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.64 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  9.9 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               46.63 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9D2H 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.10 
_refine.ls_d_res_low                             58.76 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     50694 
_refine.ls_number_reflns_R_free                  2447 
_refine.ls_number_reflns_R_work                  48247 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    76.16 
_refine.ls_percent_reflns_R_free                 4.83 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1954 
_refine.ls_R_factor_R_free                       0.2608 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1922 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.46 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 33.5130 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.4815 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.10 
_refine_hist.d_res_low                        58.76 
_refine_hist.number_atoms_solvent             381 
_refine_hist.number_atoms_total               7796 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7320 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         95 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0115  ? 7593  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0805  ? 10362 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0490  ? 1172  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0164  ? 1363  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 16.2288 ? 2812  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.10 2.14  . . 99  1954 52.45 . . . . 0.4459 . . . . . . . . . . . 0.4756 
'X-RAY DIFFRACTION' 2.14 2.19  . . 86  1863 50.10 . . . . 0.4136 . . . . . . . . . . . 0.4185 
'X-RAY DIFFRACTION' 2.19 2.24  . . 94  2061 55.51 . . . . 0.3835 . . . . . . . . . . . 0.4260 
'X-RAY DIFFRACTION' 2.24 2.30  . . 135 2013 55.45 . . . . 0.3565 . . . . . . . . . . . 0.3674 
'X-RAY DIFFRACTION' 2.30 2.36  . . 117 2182 59.13 . . . . 0.3296 . . . . . . . . . . . 0.4026 
'X-RAY DIFFRACTION' 2.36 2.43  . . 128 2372 64.32 . . . . 0.3089 . . . . . . . . . . . 0.3534 
'X-RAY DIFFRACTION' 2.43 2.51  . . 135 2514 67.71 . . . . 0.2910 . . . . . . . . . . . 0.3433 
'X-RAY DIFFRACTION' 2.51 2.60  . . 139 2645 71.22 . . . . 0.2722 . . . . . . . . . . . 0.3583 
'X-RAY DIFFRACTION' 2.60 2.70  . . 132 2727 73.48 . . . . 0.2496 . . . . . . . . . . . 0.3846 
'X-RAY DIFFRACTION' 2.70 2.82  . . 147 2972 79.69 . . . . 0.2387 . . . . . . . . . . . 0.3195 
'X-RAY DIFFRACTION' 2.82 2.97  . . 138 3152 84.08 . . . . 0.2164 . . . . . . . . . . . 0.2911 
'X-RAY DIFFRACTION' 2.97 3.16  . . 181 3366 90.95 . . . . 0.2039 . . . . . . . . . . . 0.2989 
'X-RAY DIFFRACTION' 3.16 3.40  . . 186 3530 94.97 . . . . 0.1843 . . . . . . . . . . . 0.2485 
'X-RAY DIFFRACTION' 3.40 3.74  . . 182 3630 96.85 . . . . 0.1622 . . . . . . . . . . . 0.2611 
'X-RAY DIFFRACTION' 3.74 4.29  . . 175 3704 98.93 . . . . 0.1389 . . . . . . . . . . . 0.2150 
'X-RAY DIFFRACTION' 4.29 5.40  . . 180 3760 99.34 . . . . 0.1382 . . . . . . . . . . . 0.1832 
'X-RAY DIFFRACTION' 5.40 58.76 . . 193 3802 99.18 . . . . 0.1553 . . . . . . . . . . . 0.2183 
# 
_struct.entry_id                     9D2H 
_struct.title                        
;Stigmatella aurantica bacteriophytochrome protein 2 (SaBphP2), photosensory core module, investigated at ESRF(EBS) ID29. Dark Structure.
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9D2H 
_struct_keywords.text            'Photoreceptor Kinase, Myxobacterial Phytochrome, Photosensory Core Module., SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
F N N 4 ? 
G N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q09E27_STIAD 
_struct_ref.pdbx_db_accession          Q09E27 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MPPSVSELDLSQCDREPIHLLGGIQSHGVLLAFRGPDRLLEVVSANAQALLGRPPETLLGQPVGRVLPAEVLAQWEPLVA
RGSVRVVLPAGAYRALLHESDGLTVLELEPAELQPGMEETALEVVRRLVSPLAGVKGTQALLQTAADTVRALTGFDRVMV
YRFDADWHGEVLAESKRGGMDGFLGMHFPATDIPVQARALYTRNPLRLIADARARPVPLLPPVVPALGRPLDLSNSALRS
VSPVHLEYLRNMGVGASFSLSLLKEGVLWGLIACHHLEPLHISHERRRACEVLTQLLALQLSAEERAAEASEDAHRAALL
GQLATAMGEGGTLEEVLEKESERVLALTGAAGVALLLGEEPLLVGCTPAQDEVEALVAWLATQPFQTSFHTDRLGTVYPP
LAARADVAAGILAVRLAPAAARFAIWFRPEVARTISWAGNPRKPAEPEPGHQRLHPRGSFQAWEETVRDTSLPWKRADLG
AAEGFRGALV
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9D2H A 1 ? 490 ? Q09E27 1 ? 490 ? 1 490 
2 1 9D2H B 1 ? 490 ? Q09E27 1 ? 490 ? 1 490 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6150  ? 
1 MORE         -55   ? 
1 'SSA (A^2)'  42040 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN A 12  ? GLU A 16  ? GLN A 12  GLU A 16  5 ? 5  
HELX_P HELX_P2  AA2 ALA A 47  ? GLY A 52  ? ALA A 47  GLY A 52  1 ? 6  
HELX_P HELX_P3  AA3 PRO A 54  ? LEU A 59  ? PRO A 54  LEU A 59  5 ? 6  
HELX_P HELX_P4  AA4 PRO A 62  ? LEU A 67  ? PRO A 62  LEU A 67  1 ? 6  
HELX_P HELX_P5  AA5 PRO A 68  ? GLN A 74  ? PRO A 68  GLN A 74  1 ? 7  
HELX_P HELX_P6  AA6 GLN A 74  ? GLY A 82  ? GLN A 74  GLY A 82  1 ? 9  
HELX_P HELX_P7  AA7 GLY A 116 ? SER A 130 ? GLY A 116 SER A 130 1 ? 15 
HELX_P HELX_P8  AA8 GLY A 137 ? GLY A 154 ? GLY A 137 GLY A 154 1 ? 18 
HELX_P HELX_P9  AA9 PRO A 189 ? ILE A 193 ? PRO A 189 ILE A 193 5 ? 5  
HELX_P HELX_P10 AB1 PRO A 194 ? ASN A 204 ? PRO A 194 ASN A 204 1 ? 11 
HELX_P HELX_P11 AB2 SER A 242 ? MET A 252 ? SER A 242 MET A 252 1 ? 11 
HELX_P HELX_P12 AB3 SER A 283 ? MET A 327 ? SER A 283 MET A 327 1 ? 45 
HELX_P HELX_P13 AB4 THR A 332 ? GLU A 340 ? THR A 332 GLU A 340 1 ? 9  
HELX_P HELX_P14 AB5 GLU A 340 ? LEU A 347 ? GLU A 340 LEU A 347 1 ? 8  
HELX_P HELX_P15 AB6 ALA A 369 ? ALA A 381 ? ALA A 369 ALA A 381 1 ? 13 
HELX_P HELX_P16 AB7 ARG A 393 ? VAL A 397 ? ARG A 393 VAL A 397 5 ? 5  
HELX_P HELX_P17 AB8 TYR A 398 ? ALA A 405 ? TYR A 398 ALA A 405 5 ? 8  
HELX_P HELX_P18 AB9 GLU A 448 ? GLN A 452 ? GLU A 448 GLN A 452 5 ? 5  
HELX_P HELX_P19 AC1 LYS A 475 ? LEU A 489 ? LYS A 475 LEU A 489 1 ? 15 
HELX_P HELX_P20 AC2 SER B 11  ? GLU B 16  ? SER B 11  GLU B 16  1 ? 6  
HELX_P HELX_P21 AC3 ALA B 47  ? GLY B 52  ? ALA B 47  GLY B 52  1 ? 6  
HELX_P HELX_P22 AC4 PRO B 54  ? LEU B 59  ? PRO B 54  LEU B 59  1 ? 6  
HELX_P HELX_P23 AC5 PRO B 62  ? VAL B 66  ? PRO B 62  VAL B 66  5 ? 5  
HELX_P HELX_P24 AC6 PRO B 68  ? GLN B 74  ? PRO B 68  GLN B 74  1 ? 7  
HELX_P HELX_P25 AC7 GLN B 74  ? GLY B 82  ? GLN B 74  GLY B 82  1 ? 9  
HELX_P HELX_P26 AC8 GLY B 116 ? LEU B 128 ? GLY B 116 LEU B 128 1 ? 13 
HELX_P HELX_P27 AC9 LYS B 136 ? GLY B 154 ? LYS B 136 GLY B 154 1 ? 19 
HELX_P HELX_P28 AD1 PRO B 189 ? ILE B 193 ? PRO B 189 ILE B 193 5 ? 5  
HELX_P HELX_P29 AD2 PRO B 194 ? ASN B 204 ? PRO B 194 ASN B 204 1 ? 11 
HELX_P HELX_P30 AD3 SER B 242 ? GLY B 253 ? SER B 242 GLY B 253 1 ? 12 
HELX_P HELX_P31 AD4 SER B 283 ? GLY B 328 ? SER B 283 GLY B 328 1 ? 46 
HELX_P HELX_P32 AD5 THR B 332 ? GLU B 340 ? THR B 332 GLU B 340 1 ? 9  
HELX_P HELX_P33 AD6 GLU B 340 ? LEU B 347 ? GLU B 340 LEU B 347 1 ? 8  
HELX_P HELX_P34 AD7 ALA B 369 ? THR B 382 ? ALA B 369 THR B 382 1 ? 14 
HELX_P HELX_P35 AD8 ARG B 393 ? TYR B 398 ? ARG B 393 TYR B 398 1 ? 6  
HELX_P HELX_P36 AD9 PRO B 399 ? ALA B 402 ? PRO B 399 ALA B 402 5 ? 4  
HELX_P HELX_P37 AE1 LYS B 475 ? LEU B 489 ? LYS B 475 LEU B 489 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 LEU 220 A . ? LEU 220 A PRO 221 A ? PRO 221 A 1 -5.32  
2 LEU 220 B . ? LEU 220 B PRO 221 B ? PRO 221 B 1 -11.02 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 6 ? 
AA3 ? 5 ? 
AA4 ? 2 ? 
AA5 ? 7 ? 
AA6 ? 6 ? 
AA7 ? 5 ? 
AA8 ? 2 ? 
AA9 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 23  ? ILE A 24  ? GLY A 23  ILE A 24  
AA1 2 VAL A 217 ? LEU A 220 ? VAL A 217 LEU A 220 
AA1 3 LEU A 39  ? SER A 44  ? LEU A 39  SER A 44  
AA1 4 VAL A 29  ? ARG A 34  ? VAL A 29  ARG A 34  
AA1 5 LEU A 103 ? PRO A 110 ? LEU A 103 PRO A 110 
AA1 6 GLY A 91  ? SER A 100 ? GLY A 91  SER A 100 
AA1 7 SER A 83  ? LEU A 88  ? SER A 83  LEU A 88  
AA2 1 HIS A 187 ? PHE A 188 ? HIS A 187 PHE A 188 
AA2 2 GLY A 169 ? LYS A 176 ? GLY A 169 LYS A 176 
AA2 3 ARG A 157 ? PHE A 163 ? ARG A 157 PHE A 163 
AA2 4 VAL A 267 ? HIS A 276 ? VAL A 267 HIS A 276 
AA2 5 ALA A 256 ? LYS A 264 ? ALA A 256 LYS A 264 
AA2 6 LEU A 206 ? ILE A 209 ? LEU A 206 ILE A 209 
AA3 1 LEU A 362 ? GLY A 365 ? LEU A 362 GLY A 365 
AA3 2 GLY A 352 ? LEU A 356 ? GLY A 352 LEU A 356 
AA3 3 PHE A 423 ? ARG A 428 ? PHE A 423 ARG A 428 
AA3 4 GLY A 410 ? ARG A 415 ? GLY A 410 ARG A 415 
AA3 5 SER A 388 ? THR A 391 ? SER A 388 THR A 391 
AA4 1 ARG A 433 ? ALA A 438 ? ARG A 433 ALA A 438 
AA4 2 ALA A 462 ? VAL A 467 ? ALA A 462 VAL A 467 
AA5 1 GLY B 23  ? ILE B 24  ? GLY B 23  ILE B 24  
AA5 2 VAL B 217 ? LEU B 220 ? VAL B 217 LEU B 220 
AA5 3 LEU B 39  ? SER B 44  ? LEU B 39  SER B 44  
AA5 4 VAL B 29  ? ARG B 34  ? VAL B 29  ARG B 34  
AA5 5 LEU B 103 ? PRO B 110 ? LEU B 103 PRO B 110 
AA5 6 GLY B 91  ? SER B 100 ? GLY B 91  SER B 100 
AA5 7 SER B 83  ? LEU B 88  ? SER B 83  LEU B 88  
AA6 1 HIS B 187 ? PHE B 188 ? HIS B 187 PHE B 188 
AA6 2 GLY B 169 ? LYS B 176 ? GLY B 169 LYS B 176 
AA6 3 ARG B 157 ? PHE B 163 ? ARG B 157 PHE B 163 
AA6 4 LEU B 268 ? HIS B 276 ? LEU B 268 HIS B 276 
AA6 5 ALA B 256 ? LEU B 263 ? ALA B 256 LEU B 263 
AA6 6 LEU B 206 ? ILE B 209 ? LEU B 206 ILE B 209 
AA7 1 LEU B 362 ? GLY B 365 ? LEU B 362 GLY B 365 
AA7 2 GLY B 352 ? LEU B 356 ? GLY B 352 LEU B 356 
AA7 3 PHE B 423 ? ARG B 428 ? PHE B 423 ARG B 428 
AA7 4 GLY B 410 ? ARG B 415 ? GLY B 410 ARG B 415 
AA7 5 SER B 388 ? THR B 391 ? SER B 388 THR B 391 
AA8 1 ARG B 433 ? ALA B 438 ? ARG B 433 ALA B 438 
AA8 2 ALA B 462 ? VAL B 467 ? ALA B 462 VAL B 467 
AA9 1 ALA B 445 ? PRO B 447 ? ALA B 445 PRO B 447 
AA9 2 LEU B 454 ? PRO B 456 ? LEU B 454 PRO B 456 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 24  ? N ILE A 24  O VAL A 217 ? O VAL A 217 
AA1 2 3 O LEU A 220 ? O LEU A 220 N VAL A 43  ? N VAL A 43  
AA1 3 4 O VAL A 42  ? O VAL A 42  N ALA A 32  ? N ALA A 32  
AA1 4 5 N LEU A 31  ? N LEU A 31  O LEU A 106 ? O LEU A 106 
AA1 5 6 O GLU A 109 ? O GLU A 109 N ARG A 94  ? N ARG A 94  
AA1 6 7 O ALA A 95  ? O ALA A 95  N VAL A 84  ? N VAL A 84  
AA2 1 2 O PHE A 188 ? O PHE A 188 N GLY A 169 ? N GLY A 169 
AA2 2 3 O SER A 175 ? O SER A 175 N VAL A 158 ? N VAL A 158 
AA2 3 4 N TYR A 161 ? N TYR A 161 O LEU A 271 ? O LEU A 271 
AA2 4 5 O CYS A 274 ? O CYS A 274 N PHE A 258 ? N PHE A 258 
AA2 5 6 O SER A 257 ? O SER A 257 N ILE A 209 ? N ILE A 209 
AA3 1 2 O VAL A 364 ? O VAL A 364 N VAL A 353 ? N VAL A 353 
AA3 2 3 N LEU A 356 ? N LEU A 356 O PHE A 423 ? O PHE A 423 
AA3 3 4 O TRP A 426 ? O TRP A 426 N LEU A 412 ? N LEU A 412 
AA3 4 5 O ALA A 413 ? O ALA A 413 N PHE A 389 ? N PHE A 389 
AA4 1 2 N TRP A 437 ? N TRP A 437 O TRP A 463 ? O TRP A 463 
AA5 1 2 N ILE B 24  ? N ILE B 24  O VAL B 217 ? O VAL B 217 
AA5 2 3 O LEU B 220 ? O LEU B 220 N VAL B 43  ? N VAL B 43  
AA5 3 4 O GLU B 41  ? O GLU B 41  N ALA B 32  ? N ALA B 32  
AA5 4 5 N LEU B 31  ? N LEU B 31  O LEU B 106 ? O LEU B 106 
AA5 5 6 O GLU B 109 ? O GLU B 109 N ARG B 94  ? N ARG B 94  
AA5 6 7 O TYR B 93  ? O TYR B 93  N VAL B 86  ? N VAL B 86  
AA6 1 2 O PHE B 188 ? O PHE B 188 N GLY B 169 ? N GLY B 169 
AA6 2 3 O SER B 175 ? O SER B 175 N VAL B 158 ? N VAL B 158 
AA6 3 4 N TYR B 161 ? N TYR B 161 O LEU B 271 ? O LEU B 271 
AA6 4 5 O HIS B 276 ? O HIS B 276 N ALA B 256 ? N ALA B 256 
AA6 5 6 O SER B 257 ? O SER B 257 N ILE B 209 ? N ILE B 209 
AA7 1 2 O VAL B 364 ? O VAL B 364 N VAL B 353 ? N VAL B 353 
AA7 2 3 N LEU B 356 ? N LEU B 356 O PHE B 423 ? O PHE B 423 
AA7 3 4 O TRP B 426 ? O TRP B 426 N LEU B 412 ? N LEU B 412 
AA7 4 5 O ALA B 413 ? O ALA B 413 N PHE B 389 ? N PHE B 389 
AA8 1 2 N ARG B 433 ? N ARG B 433 O VAL B 467 ? O VAL B 467 
AA9 1 2 N GLU B 446 ? N GLU B 446 O HIS B 455 ? O HIS B 455 
# 
_pdbx_entry_details.entry_id                   9D2H 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 SG  B CYS 13  ? ? CBC B BLA 501 ? ? 1.77 
2  1 SG  A CYS 13  ? ? CBC A BLA 501 ? ? 1.77 
3  1 O   B PRO 243 ? ? O   B HOH 601 ? ? 2.06 
4  1 O   A HOH 629 ? ? O   A HOH 748 ? ? 2.09 
5  1 O   A HOH 683 ? ? O   A HOH 728 ? ? 2.12 
6  1 N   B GLU 265 ? ? O   B HOH 602 ? ? 2.12 
7  1 O   A HOH 782 ? ? O   A HOH 784 ? ? 2.14 
8  1 OE2 A GLU 16  ? ? O   A HOH 601 ? ? 2.15 
9  1 O   B HOH 649 ? ? O   B HOH 660 ? ? 2.15 
10 1 O   B HOH 744 ? ? O   B HOH 774 ? ? 2.16 
11 1 O   A HOH 636 ? ? O   A HOH 678 ? ? 2.16 
12 1 OE2 A GLU 304 ? ? O   A HOH 602 ? ? 2.18 
13 1 O   B PHE 385 ? ? NH2 B ARG 415 ? ? 2.18 
14 1 O   B HOH 718 ? ? O   B HOH 758 ? ? 2.18 
15 1 OE1 B GLU 335 ? ? O   B HOH 603 ? ? 2.18 
16 1 O   A HOH 675 ? ? O   A HOH 678 ? ? 2.19 
17 1 O   B HOH 733 ? ? O   B HOH 737 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 10  ? ? -68.38  -86.70  
2  1 PRO A 17  ? ? -69.90  81.00   
3  1 ARG A 38  ? ? 39.89   54.27   
4  1 VAL A 135 ? ? -75.88  20.55   
5  1 LYS A 136 ? ? -146.70 37.60   
6  1 LEU A 233 ? ? -96.29  31.56   
7  1 SER A 242 ? ? -36.49  128.41  
8  1 MET A 327 ? ? -68.74  -177.91 
9  1 GLU A 329 ? ? -138.36 -159.05 
10 1 LEU A 333 ? ? -55.91  -75.63  
11 1 LEU A 337 ? ? -74.96  26.58   
12 1 GLU A 338 ? ? -134.14 -36.70  
13 1 GLU A 359 ? ? -72.31  -141.09 
14 1 ALA A 381 ? ? -64.30  4.08    
15 1 THR A 387 ? ? -138.49 -41.13  
16 1 THR A 396 ? ? -90.36  48.72   
17 1 VAL A 397 ? ? -176.16 -20.54  
18 1 ARG A 404 ? ? -96.09  42.59   
19 1 ALA A 408 ? ? -150.49 56.17   
20 1 PRO A 418 ? ? -70.68  -94.67  
21 1 ALA A 421 ? ? -101.37 73.08   
22 1 LYS A 443 ? ? -113.53 70.15   
23 1 LEU B 10  ? ? -49.88  89.43   
24 1 SER B 11  ? ? -109.70 -169.69 
25 1 VAL B 66  ? ? -132.63 -51.26  
26 1 ALA B 80  ? ? -60.61  -73.00  
27 1 VAL B 129 ? ? -108.54 -62.25  
28 1 SER B 130 ? ? 53.98   -174.42 
29 1 PRO B 131 ? ? -56.03  -87.47  
30 1 LYS B 136 ? ? -114.96 69.96   
31 1 PRO B 194 ? ? -67.55  -175.51 
32 1 SER B 242 ? ? -37.77  131.09  
33 1 LYS B 264 ? ? -91.23  -68.24  
34 1 LEU B 280 ? ? -163.51 119.69  
35 1 GLU B 329 ? ? -145.44 26.32   
36 1 THR B 332 ? ? -172.76 79.85   
37 1 LEU B 333 ? ? -65.81  -86.59  
38 1 GLU B 340 ? ? -109.99 47.67   
39 1 GLU B 359 ? ? -50.27  -100.49 
40 1 GLN B 386 ? ? -79.53  -71.99  
41 1 ARG B 393 ? ? -114.59 74.21   
42 1 TYR B 398 ? ? -169.72 82.32   
43 1 ALA B 405 ? ? -62.08  1.49    
44 1 VAL B 407 ? ? -146.15 -10.37  
45 1 ALA B 408 ? ? -157.36 47.76   
46 1 PRO B 418 ? ? -65.65  -92.64  
47 1 ALA B 420 ? ? 73.19   173.63  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1  1 O ? A HOH 778 ? 5.86 . 
2  1 O ? A HOH 779 ? 6.11 . 
3  1 O ? A HOH 780 ? 6.27 . 
4  1 O ? A HOH 781 ? 6.58 . 
5  1 O ? A HOH 782 ? 6.92 . 
6  1 O ? A HOH 783 ? 6.94 . 
7  1 O ? A HOH 784 ? 7.76 . 
8  1 O ? B HOH 789 ? 6.19 . 
9  1 O ? B HOH 790 ? 6.33 . 
10 1 O ? B HOH 791 ? 6.40 . 
11 1 O ? B HOH 792 ? 6.54 . 
12 1 O ? B HOH 793 ? 6.55 . 
13 1 O ? B HOH 794 ? 6.76 . 
14 1 O ? B HOH 795 ? 6.90 . 
15 1 O ? B HOH 796 ? 7.15 . 
16 1 O ? B HOH 797 ? 8.24 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1 ? A MET 1 
2  1 Y 1 A PRO 2 ? A PRO 2 
3  1 Y 1 A PRO 3 ? A PRO 3 
4  1 Y 1 A SER 4 ? A SER 4 
5  1 Y 1 A VAL 5 ? A VAL 5 
6  1 Y 1 A SER 6 ? A SER 6 
7  1 Y 1 A GLU 7 ? A GLU 7 
8  1 Y 1 A LEU 8 ? A LEU 8 
9  1 Y 1 B MET 1 ? B MET 1 
10 1 Y 1 B PRO 2 ? B PRO 2 
11 1 Y 1 B PRO 3 ? B PRO 3 
12 1 Y 1 B SER 4 ? B SER 4 
13 1 Y 1 B VAL 5 ? B VAL 5 
14 1 Y 1 B SER 6 ? B SER 6 
15 1 Y 1 B GLU 7 ? B GLU 7 
16 1 Y 1 B LEU 8 ? B LEU 8 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BEN C1   C Y N 74  
BEN C2   C Y N 75  
BEN C3   C Y N 76  
BEN C4   C Y N 77  
BEN C5   C Y N 78  
BEN C6   C Y N 79  
BEN C    C N N 80  
BEN N1   N N N 81  
BEN N2   N N N 82  
BEN H2   H N N 83  
BEN H3   H N N 84  
BEN H4   H N N 85  
BEN H5   H N N 86  
BEN H6   H N N 87  
BEN HN1  H N N 88  
BEN HN21 H N N 89  
BEN HN22 H N N 90  
BLA CHA  C N N 91  
BLA NA   N Y N 92  
BLA C1A  C Y N 93  
BLA C2A  C Y N 94  
BLA C3A  C Y N 95  
BLA C4A  C Y N 96  
BLA CMA  C N N 97  
BLA CAA  C N N 98  
BLA CBA  C N N 99  
BLA CGA  C N N 100 
BLA O1A  O N N 101 
BLA O2A  O N N 102 
BLA CHB  C N N 103 
BLA NB   N N N 104 
BLA C1B  C N N 105 
BLA C2B  C N N 106 
BLA C3B  C N N 107 
BLA C4B  C N N 108 
BLA CMB  C N N 109 
BLA OB   O N N 110 
BLA CAB  C N N 111 
BLA CBB  C N N 112 
BLA NC   N N N 113 
BLA C1C  C N N 114 
BLA C2C  C N N 115 
BLA C3C  C N N 116 
BLA C4C  C N N 117 
BLA CMC  C N N 118 
BLA OC   O N N 119 
BLA CAC  C N N 120 
BLA CBC  C N N 121 
BLA CHD  C N N 122 
BLA ND   N N N 123 
BLA C1D  C N N 124 
BLA C2D  C N N 125 
BLA C3D  C N N 126 
BLA C4D  C N N 127 
BLA CMD  C N N 128 
BLA CAD  C N N 129 
BLA CBD  C N N 130 
BLA CGD  C N N 131 
BLA O1D  O N N 132 
BLA O2D  O N N 133 
BLA HHA  H N N 134 
BLA HA   H N N 135 
BLA HMA1 H N N 136 
BLA HMA2 H N N 137 
BLA HMA3 H N N 138 
BLA HAA1 H N N 139 
BLA HAA2 H N N 140 
BLA HBA1 H N N 141 
BLA HBA2 H N N 142 
BLA H2A  H N N 143 
BLA HHB  H N N 144 
BLA HB   H N N 145 
BLA HMB1 H N N 146 
BLA HMB2 H N N 147 
BLA HMB3 H N N 148 
BLA HAB  H N N 149 
BLA HBB1 H N N 150 
BLA HBB2 H N N 151 
BLA HC   H N N 152 
BLA HMC1 H N N 153 
BLA HMC2 H N N 154 
BLA HMC3 H N N 155 
BLA HAC  H N N 156 
BLA HBC1 H N N 157 
BLA HBC2 H N N 158 
BLA HHD  H N N 159 
BLA HMD1 H N N 160 
BLA HMD2 H N N 161 
BLA HMD3 H N N 162 
BLA HAD1 H N N 163 
BLA HAD2 H N N 164 
BLA HBD1 H N N 165 
BLA HBD2 H N N 166 
BLA H2D  H N N 167 
CYS N    N N N 168 
CYS CA   C N R 169 
CYS C    C N N 170 
CYS O    O N N 171 
CYS CB   C N N 172 
CYS SG   S N N 173 
CYS OXT  O N N 174 
CYS H    H N N 175 
CYS H2   H N N 176 
CYS HA   H N N 177 
CYS HB2  H N N 178 
CYS HB3  H N N 179 
CYS HG   H N N 180 
CYS HXT  H N N 181 
GLN N    N N N 182 
GLN CA   C N S 183 
GLN C    C N N 184 
GLN O    O N N 185 
GLN CB   C N N 186 
GLN CG   C N N 187 
GLN CD   C N N 188 
GLN OE1  O N N 189 
GLN NE2  N N N 190 
GLN OXT  O N N 191 
GLN H    H N N 192 
GLN H2   H N N 193 
GLN HA   H N N 194 
GLN HB2  H N N 195 
GLN HB3  H N N 196 
GLN HG2  H N N 197 
GLN HG3  H N N 198 
GLN HE21 H N N 199 
GLN HE22 H N N 200 
GLN HXT  H N N 201 
GLU N    N N N 202 
GLU CA   C N S 203 
GLU C    C N N 204 
GLU O    O N N 205 
GLU CB   C N N 206 
GLU CG   C N N 207 
GLU CD   C N N 208 
GLU OE1  O N N 209 
GLU OE2  O N N 210 
GLU OXT  O N N 211 
GLU H    H N N 212 
GLU H2   H N N 213 
GLU HA   H N N 214 
GLU HB2  H N N 215 
GLU HB3  H N N 216 
GLU HG2  H N N 217 
GLU HG3  H N N 218 
GLU HE2  H N N 219 
GLU HXT  H N N 220 
GLY N    N N N 221 
GLY CA   C N N 222 
GLY C    C N N 223 
GLY O    O N N 224 
GLY OXT  O N N 225 
GLY H    H N N 226 
GLY H2   H N N 227 
GLY HA2  H N N 228 
GLY HA3  H N N 229 
GLY HXT  H N N 230 
HIS N    N N N 231 
HIS CA   C N S 232 
HIS C    C N N 233 
HIS O    O N N 234 
HIS CB   C N N 235 
HIS CG   C Y N 236 
HIS ND1  N Y N 237 
HIS CD2  C Y N 238 
HIS CE1  C Y N 239 
HIS NE2  N Y N 240 
HIS OXT  O N N 241 
HIS H    H N N 242 
HIS H2   H N N 243 
HIS HA   H N N 244 
HIS HB2  H N N 245 
HIS HB3  H N N 246 
HIS HD1  H N N 247 
HIS HD2  H N N 248 
HIS HE1  H N N 249 
HIS HE2  H N N 250 
HIS HXT  H N N 251 
HOH O    O N N 252 
HOH H1   H N N 253 
HOH H2   H N N 254 
ILE N    N N N 255 
ILE CA   C N S 256 
ILE C    C N N 257 
ILE O    O N N 258 
ILE CB   C N S 259 
ILE CG1  C N N 260 
ILE CG2  C N N 261 
ILE CD1  C N N 262 
ILE OXT  O N N 263 
ILE H    H N N 264 
ILE H2   H N N 265 
ILE HA   H N N 266 
ILE HB   H N N 267 
ILE HG12 H N N 268 
ILE HG13 H N N 269 
ILE HG21 H N N 270 
ILE HG22 H N N 271 
ILE HG23 H N N 272 
ILE HD11 H N N 273 
ILE HD12 H N N 274 
ILE HD13 H N N 275 
ILE HXT  H N N 276 
LEU N    N N N 277 
LEU CA   C N S 278 
LEU C    C N N 279 
LEU O    O N N 280 
LEU CB   C N N 281 
LEU CG   C N N 282 
LEU CD1  C N N 283 
LEU CD2  C N N 284 
LEU OXT  O N N 285 
LEU H    H N N 286 
LEU H2   H N N 287 
LEU HA   H N N 288 
LEU HB2  H N N 289 
LEU HB3  H N N 290 
LEU HG   H N N 291 
LEU HD11 H N N 292 
LEU HD12 H N N 293 
LEU HD13 H N N 294 
LEU HD21 H N N 295 
LEU HD22 H N N 296 
LEU HD23 H N N 297 
LEU HXT  H N N 298 
LYS N    N N N 299 
LYS CA   C N S 300 
LYS C    C N N 301 
LYS O    O N N 302 
LYS CB   C N N 303 
LYS CG   C N N 304 
LYS CD   C N N 305 
LYS CE   C N N 306 
LYS NZ   N N N 307 
LYS OXT  O N N 308 
LYS H    H N N 309 
LYS H2   H N N 310 
LYS HA   H N N 311 
LYS HB2  H N N 312 
LYS HB3  H N N 313 
LYS HG2  H N N 314 
LYS HG3  H N N 315 
LYS HD2  H N N 316 
LYS HD3  H N N 317 
LYS HE2  H N N 318 
LYS HE3  H N N 319 
LYS HZ1  H N N 320 
LYS HZ2  H N N 321 
LYS HZ3  H N N 322 
LYS HXT  H N N 323 
MET N    N N N 324 
MET CA   C N S 325 
MET C    C N N 326 
MET O    O N N 327 
MET CB   C N N 328 
MET CG   C N N 329 
MET SD   S N N 330 
MET CE   C N N 331 
MET OXT  O N N 332 
MET H    H N N 333 
MET H2   H N N 334 
MET HA   H N N 335 
MET HB2  H N N 336 
MET HB3  H N N 337 
MET HG2  H N N 338 
MET HG3  H N N 339 
MET HE1  H N N 340 
MET HE2  H N N 341 
MET HE3  H N N 342 
MET HXT  H N N 343 
PHE N    N N N 344 
PHE CA   C N S 345 
PHE C    C N N 346 
PHE O    O N N 347 
PHE CB   C N N 348 
PHE CG   C Y N 349 
PHE CD1  C Y N 350 
PHE CD2  C Y N 351 
PHE CE1  C Y N 352 
PHE CE2  C Y N 353 
PHE CZ   C Y N 354 
PHE OXT  O N N 355 
PHE H    H N N 356 
PHE H2   H N N 357 
PHE HA   H N N 358 
PHE HB2  H N N 359 
PHE HB3  H N N 360 
PHE HD1  H N N 361 
PHE HD2  H N N 362 
PHE HE1  H N N 363 
PHE HE2  H N N 364 
PHE HZ   H N N 365 
PHE HXT  H N N 366 
PRO N    N N N 367 
PRO CA   C N S 368 
PRO C    C N N 369 
PRO O    O N N 370 
PRO CB   C N N 371 
PRO CG   C N N 372 
PRO CD   C N N 373 
PRO OXT  O N N 374 
PRO H    H N N 375 
PRO HA   H N N 376 
PRO HB2  H N N 377 
PRO HB3  H N N 378 
PRO HG2  H N N 379 
PRO HG3  H N N 380 
PRO HD2  H N N 381 
PRO HD3  H N N 382 
PRO HXT  H N N 383 
SER N    N N N 384 
SER CA   C N S 385 
SER C    C N N 386 
SER O    O N N 387 
SER CB   C N N 388 
SER OG   O N N 389 
SER OXT  O N N 390 
SER H    H N N 391 
SER H2   H N N 392 
SER HA   H N N 393 
SER HB2  H N N 394 
SER HB3  H N N 395 
SER HG   H N N 396 
SER HXT  H N N 397 
THR N    N N N 398 
THR CA   C N S 399 
THR C    C N N 400 
THR O    O N N 401 
THR CB   C N R 402 
THR OG1  O N N 403 
THR CG2  C N N 404 
THR OXT  O N N 405 
THR H    H N N 406 
THR H2   H N N 407 
THR HA   H N N 408 
THR HB   H N N 409 
THR HG1  H N N 410 
THR HG21 H N N 411 
THR HG22 H N N 412 
THR HG23 H N N 413 
THR HXT  H N N 414 
TRP N    N N N 415 
TRP CA   C N S 416 
TRP C    C N N 417 
TRP O    O N N 418 
TRP CB   C N N 419 
TRP CG   C Y N 420 
TRP CD1  C Y N 421 
TRP CD2  C Y N 422 
TRP NE1  N Y N 423 
TRP CE2  C Y N 424 
TRP CE3  C Y N 425 
TRP CZ2  C Y N 426 
TRP CZ3  C Y N 427 
TRP CH2  C Y N 428 
TRP OXT  O N N 429 
TRP H    H N N 430 
TRP H2   H N N 431 
TRP HA   H N N 432 
TRP HB2  H N N 433 
TRP HB3  H N N 434 
TRP HD1  H N N 435 
TRP HE1  H N N 436 
TRP HE3  H N N 437 
TRP HZ2  H N N 438 
TRP HZ3  H N N 439 
TRP HH2  H N N 440 
TRP HXT  H N N 441 
TYR N    N N N 442 
TYR CA   C N S 443 
TYR C    C N N 444 
TYR O    O N N 445 
TYR CB   C N N 446 
TYR CG   C Y N 447 
TYR CD1  C Y N 448 
TYR CD2  C Y N 449 
TYR CE1  C Y N 450 
TYR CE2  C Y N 451 
TYR CZ   C Y N 452 
TYR OH   O N N 453 
TYR OXT  O N N 454 
TYR H    H N N 455 
TYR H2   H N N 456 
TYR HA   H N N 457 
TYR HB2  H N N 458 
TYR HB3  H N N 459 
TYR HD1  H N N 460 
TYR HD2  H N N 461 
TYR HE1  H N N 462 
TYR HE2  H N N 463 
TYR HH   H N N 464 
TYR HXT  H N N 465 
VAL N    N N N 466 
VAL CA   C N S 467 
VAL C    C N N 468 
VAL O    O N N 469 
VAL CB   C N N 470 
VAL CG1  C N N 471 
VAL CG2  C N N 472 
VAL OXT  O N N 473 
VAL H    H N N 474 
VAL H2   H N N 475 
VAL HA   H N N 476 
VAL HB   H N N 477 
VAL HG11 H N N 478 
VAL HG12 H N N 479 
VAL HG13 H N N 480 
VAL HG21 H N N 481 
VAL HG22 H N N 482 
VAL HG23 H N N 483 
VAL HXT  H N N 484 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BEN C1  C2   doub Y N 70  
BEN C1  C6   sing Y N 71  
BEN C1  C    sing N N 72  
BEN C2  C3   sing Y N 73  
BEN C2  H2   sing N N 74  
BEN C3  C4   doub Y N 75  
BEN C3  H3   sing N N 76  
BEN C4  C5   sing Y N 77  
BEN C4  H4   sing N N 78  
BEN C5  C6   doub Y N 79  
BEN C5  H5   sing N N 80  
BEN C6  H6   sing N N 81  
BEN C   N1   doub N E 82  
BEN C   N2   sing N N 83  
BEN N1  HN1  sing N N 84  
BEN N2  HN21 sing N N 85  
BEN N2  HN22 sing N N 86  
BLA CHA C1A  sing N N 87  
BLA CHA C4D  doub N Z 88  
BLA CHA HHA  sing N N 89  
BLA NA  C1A  sing Y N 90  
BLA NA  C4A  sing Y N 91  
BLA NA  HA   sing N N 92  
BLA C1A C2A  doub Y N 93  
BLA C2A C3A  sing Y N 94  
BLA C2A CAA  sing N N 95  
BLA C3A C4A  doub Y N 96  
BLA C3A CMA  sing N N 97  
BLA C4A CHB  sing N N 98  
BLA CMA HMA1 sing N N 99  
BLA CMA HMA2 sing N N 100 
BLA CMA HMA3 sing N N 101 
BLA CAA CBA  sing N N 102 
BLA CAA HAA1 sing N N 103 
BLA CAA HAA2 sing N N 104 
BLA CBA CGA  sing N N 105 
BLA CBA HBA1 sing N N 106 
BLA CBA HBA2 sing N N 107 
BLA CGA O1A  doub N N 108 
BLA CGA O2A  sing N N 109 
BLA O2A H2A  sing N N 110 
BLA CHB C1B  doub N Z 111 
BLA CHB HHB  sing N N 112 
BLA NB  C1B  sing N N 113 
BLA NB  C4B  sing N N 114 
BLA NB  HB   sing N N 115 
BLA C1B C2B  sing N N 116 
BLA C2B C3B  doub N N 117 
BLA C2B CMB  sing N N 118 
BLA C3B C4B  sing N N 119 
BLA C3B CAB  sing N N 120 
BLA C4B OB   doub N N 121 
BLA CMB HMB1 sing N N 122 
BLA CMB HMB2 sing N N 123 
BLA CMB HMB3 sing N N 124 
BLA CAB CBB  doub N N 125 
BLA CAB HAB  sing N N 126 
BLA CBB HBB1 sing N N 127 
BLA CBB HBB2 sing N N 128 
BLA NC  C1C  sing N N 129 
BLA NC  C4C  sing N N 130 
BLA NC  HC   sing N N 131 
BLA C1C C2C  sing N N 132 
BLA C1C OC   doub N N 133 
BLA C2C C3C  doub N N 134 
BLA C2C CMC  sing N N 135 
BLA C3C C4C  sing N N 136 
BLA C3C CAC  sing N N 137 
BLA C4C CHD  doub N Z 138 
BLA CMC HMC1 sing N N 139 
BLA CMC HMC2 sing N N 140 
BLA CMC HMC3 sing N N 141 
BLA CAC CBC  doub N N 142 
BLA CAC HAC  sing N N 143 
BLA CBC HBC1 sing N N 144 
BLA CBC HBC2 sing N N 145 
BLA CHD C1D  sing N N 146 
BLA CHD HHD  sing N N 147 
BLA ND  C1D  doub N N 148 
BLA ND  C4D  sing N N 149 
BLA C1D C2D  sing N N 150 
BLA C2D C3D  doub N N 151 
BLA C2D CMD  sing N N 152 
BLA C3D C4D  sing N N 153 
BLA C3D CAD  sing N N 154 
BLA CMD HMD1 sing N N 155 
BLA CMD HMD2 sing N N 156 
BLA CMD HMD3 sing N N 157 
BLA CAD CBD  sing N N 158 
BLA CAD HAD1 sing N N 159 
BLA CAD HAD2 sing N N 160 
BLA CBD CGD  sing N N 161 
BLA CBD HBD1 sing N N 162 
BLA CBD HBD2 sing N N 163 
BLA CGD O1D  doub N N 164 
BLA CGD O2D  sing N N 165 
BLA O2D H2D  sing N N 166 
CYS N   CA   sing N N 167 
CYS N   H    sing N N 168 
CYS N   H2   sing N N 169 
CYS CA  C    sing N N 170 
CYS CA  CB   sing N N 171 
CYS CA  HA   sing N N 172 
CYS C   O    doub N N 173 
CYS C   OXT  sing N N 174 
CYS CB  SG   sing N N 175 
CYS CB  HB2  sing N N 176 
CYS CB  HB3  sing N N 177 
CYS SG  HG   sing N N 178 
CYS OXT HXT  sing N N 179 
GLN N   CA   sing N N 180 
GLN N   H    sing N N 181 
GLN N   H2   sing N N 182 
GLN CA  C    sing N N 183 
GLN CA  CB   sing N N 184 
GLN CA  HA   sing N N 185 
GLN C   O    doub N N 186 
GLN C   OXT  sing N N 187 
GLN CB  CG   sing N N 188 
GLN CB  HB2  sing N N 189 
GLN CB  HB3  sing N N 190 
GLN CG  CD   sing N N 191 
GLN CG  HG2  sing N N 192 
GLN CG  HG3  sing N N 193 
GLN CD  OE1  doub N N 194 
GLN CD  NE2  sing N N 195 
GLN NE2 HE21 sing N N 196 
GLN NE2 HE22 sing N N 197 
GLN OXT HXT  sing N N 198 
GLU N   CA   sing N N 199 
GLU N   H    sing N N 200 
GLU N   H2   sing N N 201 
GLU CA  C    sing N N 202 
GLU CA  CB   sing N N 203 
GLU CA  HA   sing N N 204 
GLU C   O    doub N N 205 
GLU C   OXT  sing N N 206 
GLU CB  CG   sing N N 207 
GLU CB  HB2  sing N N 208 
GLU CB  HB3  sing N N 209 
GLU CG  CD   sing N N 210 
GLU CG  HG2  sing N N 211 
GLU CG  HG3  sing N N 212 
GLU CD  OE1  doub N N 213 
GLU CD  OE2  sing N N 214 
GLU OE2 HE2  sing N N 215 
GLU OXT HXT  sing N N 216 
GLY N   CA   sing N N 217 
GLY N   H    sing N N 218 
GLY N   H2   sing N N 219 
GLY CA  C    sing N N 220 
GLY CA  HA2  sing N N 221 
GLY CA  HA3  sing N N 222 
GLY C   O    doub N N 223 
GLY C   OXT  sing N N 224 
GLY OXT HXT  sing N N 225 
HIS N   CA   sing N N 226 
HIS N   H    sing N N 227 
HIS N   H2   sing N N 228 
HIS CA  C    sing N N 229 
HIS CA  CB   sing N N 230 
HIS CA  HA   sing N N 231 
HIS C   O    doub N N 232 
HIS C   OXT  sing N N 233 
HIS CB  CG   sing N N 234 
HIS CB  HB2  sing N N 235 
HIS CB  HB3  sing N N 236 
HIS CG  ND1  sing Y N 237 
HIS CG  CD2  doub Y N 238 
HIS ND1 CE1  doub Y N 239 
HIS ND1 HD1  sing N N 240 
HIS CD2 NE2  sing Y N 241 
HIS CD2 HD2  sing N N 242 
HIS CE1 NE2  sing Y N 243 
HIS CE1 HE1  sing N N 244 
HIS NE2 HE2  sing N N 245 
HIS OXT HXT  sing N N 246 
HOH O   H1   sing N N 247 
HOH O   H2   sing N N 248 
ILE N   CA   sing N N 249 
ILE N   H    sing N N 250 
ILE N   H2   sing N N 251 
ILE CA  C    sing N N 252 
ILE CA  CB   sing N N 253 
ILE CA  HA   sing N N 254 
ILE C   O    doub N N 255 
ILE C   OXT  sing N N 256 
ILE CB  CG1  sing N N 257 
ILE CB  CG2  sing N N 258 
ILE CB  HB   sing N N 259 
ILE CG1 CD1  sing N N 260 
ILE CG1 HG12 sing N N 261 
ILE CG1 HG13 sing N N 262 
ILE CG2 HG21 sing N N 263 
ILE CG2 HG22 sing N N 264 
ILE CG2 HG23 sing N N 265 
ILE CD1 HD11 sing N N 266 
ILE CD1 HD12 sing N N 267 
ILE CD1 HD13 sing N N 268 
ILE OXT HXT  sing N N 269 
LEU N   CA   sing N N 270 
LEU N   H    sing N N 271 
LEU N   H2   sing N N 272 
LEU CA  C    sing N N 273 
LEU CA  CB   sing N N 274 
LEU CA  HA   sing N N 275 
LEU C   O    doub N N 276 
LEU C   OXT  sing N N 277 
LEU CB  CG   sing N N 278 
LEU CB  HB2  sing N N 279 
LEU CB  HB3  sing N N 280 
LEU CG  CD1  sing N N 281 
LEU CG  CD2  sing N N 282 
LEU CG  HG   sing N N 283 
LEU CD1 HD11 sing N N 284 
LEU CD1 HD12 sing N N 285 
LEU CD1 HD13 sing N N 286 
LEU CD2 HD21 sing N N 287 
LEU CD2 HD22 sing N N 288 
LEU CD2 HD23 sing N N 289 
LEU OXT HXT  sing N N 290 
LYS N   CA   sing N N 291 
LYS N   H    sing N N 292 
LYS N   H2   sing N N 293 
LYS CA  C    sing N N 294 
LYS CA  CB   sing N N 295 
LYS CA  HA   sing N N 296 
LYS C   O    doub N N 297 
LYS C   OXT  sing N N 298 
LYS CB  CG   sing N N 299 
LYS CB  HB2  sing N N 300 
LYS CB  HB3  sing N N 301 
LYS CG  CD   sing N N 302 
LYS CG  HG2  sing N N 303 
LYS CG  HG3  sing N N 304 
LYS CD  CE   sing N N 305 
LYS CD  HD2  sing N N 306 
LYS CD  HD3  sing N N 307 
LYS CE  NZ   sing N N 308 
LYS CE  HE2  sing N N 309 
LYS CE  HE3  sing N N 310 
LYS NZ  HZ1  sing N N 311 
LYS NZ  HZ2  sing N N 312 
LYS NZ  HZ3  sing N N 313 
LYS OXT HXT  sing N N 314 
MET N   CA   sing N N 315 
MET N   H    sing N N 316 
MET N   H2   sing N N 317 
MET CA  C    sing N N 318 
MET CA  CB   sing N N 319 
MET CA  HA   sing N N 320 
MET C   O    doub N N 321 
MET C   OXT  sing N N 322 
MET CB  CG   sing N N 323 
MET CB  HB2  sing N N 324 
MET CB  HB3  sing N N 325 
MET CG  SD   sing N N 326 
MET CG  HG2  sing N N 327 
MET CG  HG3  sing N N 328 
MET SD  CE   sing N N 329 
MET CE  HE1  sing N N 330 
MET CE  HE2  sing N N 331 
MET CE  HE3  sing N N 332 
MET OXT HXT  sing N N 333 
PHE N   CA   sing N N 334 
PHE N   H    sing N N 335 
PHE N   H2   sing N N 336 
PHE CA  C    sing N N 337 
PHE CA  CB   sing N N 338 
PHE CA  HA   sing N N 339 
PHE C   O    doub N N 340 
PHE C   OXT  sing N N 341 
PHE CB  CG   sing N N 342 
PHE CB  HB2  sing N N 343 
PHE CB  HB3  sing N N 344 
PHE CG  CD1  doub Y N 345 
PHE CG  CD2  sing Y N 346 
PHE CD1 CE1  sing Y N 347 
PHE CD1 HD1  sing N N 348 
PHE CD2 CE2  doub Y N 349 
PHE CD2 HD2  sing N N 350 
PHE CE1 CZ   doub Y N 351 
PHE CE1 HE1  sing N N 352 
PHE CE2 CZ   sing Y N 353 
PHE CE2 HE2  sing N N 354 
PHE CZ  HZ   sing N N 355 
PHE OXT HXT  sing N N 356 
PRO N   CA   sing N N 357 
PRO N   CD   sing N N 358 
PRO N   H    sing N N 359 
PRO CA  C    sing N N 360 
PRO CA  CB   sing N N 361 
PRO CA  HA   sing N N 362 
PRO C   O    doub N N 363 
PRO C   OXT  sing N N 364 
PRO CB  CG   sing N N 365 
PRO CB  HB2  sing N N 366 
PRO CB  HB3  sing N N 367 
PRO CG  CD   sing N N 368 
PRO CG  HG2  sing N N 369 
PRO CG  HG3  sing N N 370 
PRO CD  HD2  sing N N 371 
PRO CD  HD3  sing N N 372 
PRO OXT HXT  sing N N 373 
SER N   CA   sing N N 374 
SER N   H    sing N N 375 
SER N   H2   sing N N 376 
SER CA  C    sing N N 377 
SER CA  CB   sing N N 378 
SER CA  HA   sing N N 379 
SER C   O    doub N N 380 
SER C   OXT  sing N N 381 
SER CB  OG   sing N N 382 
SER CB  HB2  sing N N 383 
SER CB  HB3  sing N N 384 
SER OG  HG   sing N N 385 
SER OXT HXT  sing N N 386 
THR N   CA   sing N N 387 
THR N   H    sing N N 388 
THR N   H2   sing N N 389 
THR CA  C    sing N N 390 
THR CA  CB   sing N N 391 
THR CA  HA   sing N N 392 
THR C   O    doub N N 393 
THR C   OXT  sing N N 394 
THR CB  OG1  sing N N 395 
THR CB  CG2  sing N N 396 
THR CB  HB   sing N N 397 
THR OG1 HG1  sing N N 398 
THR CG2 HG21 sing N N 399 
THR CG2 HG22 sing N N 400 
THR CG2 HG23 sing N N 401 
THR OXT HXT  sing N N 402 
TRP N   CA   sing N N 403 
TRP N   H    sing N N 404 
TRP N   H2   sing N N 405 
TRP CA  C    sing N N 406 
TRP CA  CB   sing N N 407 
TRP CA  HA   sing N N 408 
TRP C   O    doub N N 409 
TRP C   OXT  sing N N 410 
TRP CB  CG   sing N N 411 
TRP CB  HB2  sing N N 412 
TRP CB  HB3  sing N N 413 
TRP CG  CD1  doub Y N 414 
TRP CG  CD2  sing Y N 415 
TRP CD1 NE1  sing Y N 416 
TRP CD1 HD1  sing N N 417 
TRP CD2 CE2  doub Y N 418 
TRP CD2 CE3  sing Y N 419 
TRP NE1 CE2  sing Y N 420 
TRP NE1 HE1  sing N N 421 
TRP CE2 CZ2  sing Y N 422 
TRP CE3 CZ3  doub Y N 423 
TRP CE3 HE3  sing N N 424 
TRP CZ2 CH2  doub Y N 425 
TRP CZ2 HZ2  sing N N 426 
TRP CZ3 CH2  sing Y N 427 
TRP CZ3 HZ3  sing N N 428 
TRP CH2 HH2  sing N N 429 
TRP OXT HXT  sing N N 430 
TYR N   CA   sing N N 431 
TYR N   H    sing N N 432 
TYR N   H2   sing N N 433 
TYR CA  C    sing N N 434 
TYR CA  CB   sing N N 435 
TYR CA  HA   sing N N 436 
TYR C   O    doub N N 437 
TYR C   OXT  sing N N 438 
TYR CB  CG   sing N N 439 
TYR CB  HB2  sing N N 440 
TYR CB  HB3  sing N N 441 
TYR CG  CD1  doub Y N 442 
TYR CG  CD2  sing Y N 443 
TYR CD1 CE1  sing Y N 444 
TYR CD1 HD1  sing N N 445 
TYR CD2 CE2  doub Y N 446 
TYR CD2 HD2  sing N N 447 
TYR CE1 CZ   doub Y N 448 
TYR CE1 HE1  sing N N 449 
TYR CE2 CZ   sing Y N 450 
TYR CE2 HE2  sing N N 451 
TYR CZ  OH   sing N N 452 
TYR OH  HH   sing N N 453 
TYR OXT HXT  sing N N 454 
VAL N   CA   sing N N 455 
VAL N   H    sing N N 456 
VAL N   H2   sing N N 457 
VAL CA  C    sing N N 458 
VAL CA  CB   sing N N 459 
VAL CA  HA   sing N N 460 
VAL C   O    doub N N 461 
VAL C   OXT  sing N N 462 
VAL CB  CG1  sing N N 463 
VAL CB  CG2  sing N N 464 
VAL CB  HB   sing N N 465 
VAL CG1 HG11 sing N N 466 
VAL CG1 HG12 sing N N 467 
VAL CG1 HG13 sing N N 468 
VAL CG2 HG21 sing N N 469 
VAL CG2 HG22 sing N N 470 
VAL CG2 HG23 sing N N 471 
VAL OXT HXT  sing N N 472 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Science Foundation (NSF, United States)' 'United States' 1231306 1 
'National Science Foundation (NSF, United States)' 'United States' 2423601 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6PTQ 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_serial_crystallography_data_reduction.diffrn_id             1 
_pdbx_serial_crystallography_data_reduction.frames_total          ? 
_pdbx_serial_crystallography_data_reduction.xfel_pulse_events     ? 
_pdbx_serial_crystallography_data_reduction.frame_hits            ? 
_pdbx_serial_crystallography_data_reduction.crystal_hits          252933 
_pdbx_serial_crystallography_data_reduction.droplet_hits          ? 
_pdbx_serial_crystallography_data_reduction.frames_failed_index   ? 
_pdbx_serial_crystallography_data_reduction.frames_indexed        ? 
_pdbx_serial_crystallography_data_reduction.lattices_indexed      83498 
_pdbx_serial_crystallography_data_reduction.xfel_run_numbers      ? 
_pdbx_serial_crystallography_data_reduction.lattices_merged       ? 
# 
_pdbx_serial_crystallography_measurement.diffrn_id                    1 
_pdbx_serial_crystallography_measurement.pulse_energy                 ? 
_pdbx_serial_crystallography_measurement.pulse_duration               ? 
_pdbx_serial_crystallography_measurement.xfel_pulse_repetition_rate   ? 
_pdbx_serial_crystallography_measurement.pulse_photon_energy          ? 
_pdbx_serial_crystallography_measurement.photons_per_pulse            ? 
_pdbx_serial_crystallography_measurement.source_size                  8 
_pdbx_serial_crystallography_measurement.source_distance              ? 
_pdbx_serial_crystallography_measurement.focal_spot_size              ? 
_pdbx_serial_crystallography_measurement.collimation                  ? 
_pdbx_serial_crystallography_measurement.collection_time_total        ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   chip 
_pdbx_serial_crystallography_sample_delivery.method        'fixed target' 
# 
_pdbx_serial_crystallography_sample_delivery_fixed_target.diffrn_id                       1 
_pdbx_serial_crystallography_sample_delivery_fixed_target.description                     'chip scanning' 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_holding                  mylar 
_pdbx_serial_crystallography_sample_delivery_fixed_target.support_base                    ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_unit_size                ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.crystals_per_unit               ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_solvent                  ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.sample_dehydration_prevention   ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.motion_control                  ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.velocity_horizontal             ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.velocity_vertical               ? 
_pdbx_serial_crystallography_sample_delivery_fixed_target.details                         ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9D2H 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011949 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003797 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011990 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012079 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP A 1 9   ? -42.63800 14.88800  -3.34200  1.000 80.23813  ? 9   ASP A N   1 
ATOM   2    C CA  . ASP A 1 9   ? -42.83900 13.62300  -2.63700  1.000 78.22942  ? 9   ASP A CA  1 
ATOM   3    C C   . ASP A 1 9   ? -43.09600 13.86400  -1.14200  1.000 81.26815  ? 9   ASP A C   1 
ATOM   4    O O   . ASP A 1 9   ? -42.73000 14.91400  -0.59500  1.000 80.03754  ? 9   ASP A O   1 
ATOM   5    C CB  . ASP A 1 9   ? -41.63400 12.69200  -2.84500  1.000 71.60316  ? 9   ASP A CB  1 
ATOM   6    C CG  . ASP A 1 9   ? -41.73300 11.87400  -4.13300  1.000 75.67823  ? 9   ASP A CG  1 
ATOM   7    O OD1 . ASP A 1 9   ? -42.65200 11.02600  -4.23700  1.000 76.63233  ? 9   ASP A OD1 1 
ATOM   8    O OD2 . ASP A 1 9   ? -40.89500 12.08200  -5.04300  1.000 73.34550  ? 9   ASP A OD2 1 
ATOM   9    N N   . LEU A 1 10  ? -43.70800 12.86800  -0.49100  1.000 81.64899  ? 10  LEU A N   1 
ATOM   10   C CA  . LEU A 1 10  ? -44.33900 13.03300  0.81600   1.000 82.81955  ? 10  LEU A CA  1 
ATOM   11   C C   . LEU A 1 10  ? -43.34200 13.28900  1.94100   1.000 75.65525  ? 10  LEU A C   1 
ATOM   12   O O   . LEU A 1 10  ? -43.06500 14.44700  2.28800   1.000 72.30266  ? 10  LEU A O   1 
ATOM   13   C CB  . LEU A 1 10  ? -45.19100 11.79700  1.15000   1.000 80.90434  ? 10  LEU A CB  1 
ATOM   14   C CG  . LEU A 1 10  ? -46.24900 11.35700  0.12500   1.000 82.76872  ? 10  LEU A CG  1 
ATOM   15   C CD1 . LEU A 1 10  ? -45.71100 10.28100  -0.81200  1.000 82.07617  ? 10  LEU A CD1 1 
ATOM   16   C CD2 . LEU A 1 10  ? -47.52600 10.88000  0.80700   1.000 90.63606  ? 10  LEU A CD2 1 
ATOM   17   N N   . SER A 1 11  ? -42.81700 12.21200  2.52200   1.000 69.11825  ? 11  SER A N   1 
ATOM   18   C CA  . SER A 1 11  ? -41.98500 12.31300  3.71000   1.000 65.12881  ? 11  SER A CA  1 
ATOM   19   C C   . SER A 1 11  ? -40.77500 13.21600  3.47600   1.000 63.39657  ? 11  SER A C   1 
ATOM   20   O O   . SER A 1 11  ? -40.40100 13.55100  2.34200   1.000 59.06759  ? 11  SER A O   1 
ATOM   21   C CB  . SER A 1 11  ? -41.51600 10.92300  4.15400   1.000 63.01480  ? 11  SER A CB  1 
ATOM   22   O OG  . SER A 1 11  ? -42.53700 10.23200  4.86300   1.000 69.55276  ? 11  SER A OG  1 
ATOM   23   N N   . GLN A 1 12  ? -40.17300 13.63100  4.58700   1.000 58.49865  ? 12  GLN A N   1 
ATOM   24   C CA  . GLN A 1 12  ? -38.80300 14.11100  4.53500   1.000 57.05939  ? 12  GLN A CA  1 
ATOM   25   C C   . GLN A 1 12  ? -37.83700 13.00000  4.14300   1.000 49.20646  ? 12  GLN A C   1 
ATOM   26   O O   . GLN A 1 12  ? -36.70100 13.28900  3.75000   1.000 50.54346  ? 12  GLN A O   1 
ATOM   27   C CB  . GLN A 1 12  ? -38.41600 14.69700  5.89100   1.000 66.33315  ? 12  GLN A CB  1 
ATOM   28   C CG  . GLN A 1 12  ? -39.42000 15.70400  6.43100   1.000 73.23285  ? 12  GLN A CG  1 
ATOM   29   C CD  . GLN A 1 12  ? -38.76100 16.98100  6.95500   1.000 88.34095  ? 12  GLN A CD  1 
ATOM   30   O OE1 . GLN A 1 12  ? -37.52600 17.09200  6.99400   1.000 88.17849  ? 12  GLN A OE1 1 
ATOM   31   N NE2 . GLN A 1 12  ? -39.58600 17.95600  7.35900   1.000 82.57114  ? 12  GLN A NE2 1 
ATOM   32   N N   . CYS A 1 13  ? -38.25600 11.73400  4.26100   1.000 45.85388  ? 13  CYS A N   1 
ATOM   33   C CA  . CYS A 1 13  ? -37.42400 10.62000  3.81300   1.000 46.87816  ? 13  CYS A CA  1 
ATOM   34   C C   . CYS A 1 13  ? -36.99200 10.79400  2.36400   1.000 48.78942  ? 13  CYS A C   1 
ATOM   35   O O   . CYS A 1 13  ? -35.84000 10.51400  2.00900   1.000 45.12223  ? 13  CYS A O   1 
ATOM   36   C CB  . CYS A 1 13  ? -38.17600 9.29600   3.95600   1.000 44.13107  ? 13  CYS A CB  1 
ATOM   37   S SG  . CYS A 1 13  ? -38.53700 8.78200   5.63900   1.000 40.52906  ? 13  CYS A SG  1 
ATOM   38   N N   . ASP A 1 14  ? -37.91800 11.23200  1.50800   1.000 48.12391  ? 14  ASP A N   1 
ATOM   39   C CA  . ASP A 1 14  ? -37.66400 11.35200  0.08200   1.000 45.16836  ? 14  ASP A CA  1 
ATOM   40   C C   . ASP A 1 14  ? -36.79400 12.54400  -0.26500  1.000 41.79442  ? 14  ASP A C   1 
ATOM   41   O O   . ASP A 1 14  ? -36.26200 12.60300  -1.37700  1.000 33.87843  ? 14  ASP A O   1 
ATOM   42   C CB  . ASP A 1 14  ? -38.98200 11.47500  -0.67000  1.000 47.63586  ? 14  ASP A CB  1 
ATOM   43   C CG  . ASP A 1 14  ? -39.89900 10.31400  -0.41200  1.000 54.95343  ? 14  ASP A CG  1 
ATOM   44   O OD1 . ASP A 1 14  ? -39.40000 9.16400   -0.34800  1.000 54.77476  ? 14  ASP A OD1 1 
ATOM   45   O OD2 . ASP A 1 14  ? -41.11900 10.55500  -0.28100  1.000 63.43391  ? 14  ASP A OD2 1 
ATOM   46   N N   . ARG A 1 15  ? -36.64800 13.49300  0.64300   1.000 44.12169  ? 15  ARG A N   1 
ATOM   47   C CA  . ARG A 1 15  ? -36.02400 14.75800  0.29100   1.000 47.59935  ? 15  ARG A CA  1 
ATOM   48   C C   . ARG A 1 15  ? -34.50700 14.75700  0.43300   1.000 38.11995  ? 15  ARG A C   1 
ATOM   49   O O   . ARG A 1 15  ? -33.87500 15.71100  -0.01700  1.000 42.58911  ? 15  ARG A O   1 
ATOM   50   C CB  . ARG A 1 15  ? -36.61400 15.89000  1.14300   1.000 49.49471  ? 15  ARG A CB  1 
ATOM   51   C CG  . ARG A 1 15  ? -37.86800 16.50100  0.54200   1.000 54.05147  ? 15  ARG A CG  1 
ATOM   52   C CD  . ARG A 1 15  ? -38.38300 17.67400  1.37700   1.000 64.54281  ? 15  ARG A CD  1 
ATOM   53   N NE  . ARG A 1 15  ? -39.61500 17.33300  2.08800   1.000 79.64739  ? 15  ARG A NE  1 
ATOM   54   C CZ  . ARG A 1 15  ? -40.81800 17.25400  1.52300   1.000 74.80801  ? 15  ARG A CZ  1 
ATOM   55   N NH1 . ARG A 1 15  ? -40.99000 17.45900  0.22400   1.000 67.08133  ? 15  ARG A NH1 1 
ATOM   56   N NH2 . ARG A 1 15  ? -41.87400 16.95900  2.28000   1.000 72.89414  ? 15  ARG A NH2 1 
ATOM   57   N N   . GLU A 1 16  ? -33.90700 13.73000  1.02400   1.000 36.29681  ? 16  GLU A N   1 
ATOM   58   C CA  . GLU A 1 16  ? -32.48300 13.80700  1.36600   1.000 32.93230  ? 16  GLU A CA  1 
ATOM   59   C C   . GLU A 1 16  ? -31.61800 13.65900  0.12000   1.000 37.38875  ? 16  GLU A C   1 
ATOM   60   O O   . GLU A 1 16  ? -31.65400 12.60500  -0.53000  1.000 34.12227  ? 16  GLU A O   1 
ATOM   61   C CB  . GLU A 1 16  ? -32.11800 12.74500  2.38900   1.000 33.79207  ? 16  GLU A CB  1 
ATOM   62   C CG  . GLU A 1 16  ? -30.70400 12.89100  2.95300   1.000 32.36204  ? 16  GLU A CG  1 
ATOM   63   C CD  . GLU A 1 16  ? -30.34200 11.77300  3.94300   1.000 34.32244  ? 16  GLU A CD  1 
ATOM   64   O OE1 . GLU A 1 16  ? -30.97900 10.68900  3.93800   1.000 31.80935  ? 16  GLU A OE1 1 
ATOM   65   O OE2 . GLU A 1 16  ? -29.42000 11.98600  4.74700   1.000 35.45867  ? 16  GLU A OE2 1 
ATOM   66   N N   . PRO A 1 17  ? -30.83700 14.67700  -0.25400  1.000 35.72948  ? 17  PRO A N   1 
ATOM   67   C CA  . PRO A 1 17  ? -29.93300 14.53200  -1.40400  1.000 32.82575  ? 17  PRO A CA  1 
ATOM   68   C C   . PRO A 1 17  ? -28.79100 13.58200  -1.08700  1.000 33.01482  ? 17  PRO A C   1 
ATOM   69   O O   . PRO A 1 17  ? -27.68500 14.03200  -0.76500  1.000 34.77051  ? 17  PRO A O   1 
ATOM   70   C CB  . PRO A 1 17  ? -29.42100 15.96000  -1.63600  1.000 27.98298  ? 17  PRO A CB  1 
ATOM   71   C CG  . PRO A 1 17  ? -29.45200 16.57300  -0.26300  1.000 34.96666  ? 17  PRO A CG  1 
ATOM   72   C CD  . PRO A 1 17  ? -30.62900 15.94400  0.47000   1.000 28.79440  ? 17  PRO A CD  1 
ATOM   73   N N   . ILE A 1 18  ? -29.04400 12.27100  -1.18000  1.000 34.43328  ? 18  ILE A N   1 
ATOM   74   C CA  . ILE A 1 18  ? -28.07300 11.27300  -0.73800  1.000 32.31729  ? 18  ILE A CA  1 
ATOM   75   C C   . ILE A 1 18  ? -26.84200 11.21400  -1.62400  1.000 30.92828  ? 18  ILE A C   1 
ATOM   76   O O   . ILE A 1 18  ? -25.85000 10.57300  -1.25200  1.000 31.96198  ? 18  ILE A O   1 
ATOM   77   C CB  . ILE A 1 18  ? -28.67400 9.85300   -0.67600  1.000 29.36976  ? 18  ILE A CB  1 
ATOM   78   C CG1 . ILE A 1 18  ? -29.05900 9.37900   -2.07400  1.000 27.94922  ? 18  ILE A CG1 1 
ATOM   79   C CG2 . ILE A 1 18  ? -29.83800 9.76800   0.32400   1.000 32.12774  ? 18  ILE A CG2 1 
ATOM   80   C CD1 . ILE A 1 18  ? -29.64400 7.98600   -2.10600  1.000 28.37158  ? 18  ILE A CD1 1 
ATOM   81   N N   . HIS A 1 19  ? -26.88200 11.85100  -2.78300  1.000 27.44728  ? 19  HIS A N   1 
ATOM   82   C CA  . HIS A 1 19  ? -25.74100 11.89700  -3.67800  1.000 29.29622  ? 19  HIS A CA  1 
ATOM   83   C C   . HIS A 1 19  ? -24.90900 13.15000  -3.47900  1.000 30.23319  ? 19  HIS A C   1 
ATOM   84   O O   . HIS A 1 19  ? -23.85200 13.29300  -4.10200  1.000 30.56371  ? 19  HIS A O   1 
ATOM   85   C CB  . HIS A 1 19  ? -26.21100 11.81400  -5.13000  1.000 28.99809  ? 19  HIS A CB  1 
ATOM   86   C CG  . HIS A 1 19  ? -26.98800 13.00600  -5.57900  1.000 32.51690  ? 19  HIS A CG  1 
ATOM   87   N ND1 . HIS A 1 19  ? -28.22400 13.32800  -5.05600  1.000 35.43149  ? 19  HIS A ND1 1 
ATOM   88   C CD2 . HIS A 1 19  ? -26.71700 13.94400  -6.51600  1.000 30.87113  ? 19  HIS A CD2 1 
ATOM   89   C CE1 . HIS A 1 19  ? -28.67500 14.42300  -5.64200  1.000 33.79350  ? 19  HIS A CE1 1 
ATOM   90   N NE2 . HIS A 1 19  ? -27.77800 14.81700  -6.53000  1.000 37.20371  ? 19  HIS A NE2 1 
ATOM   91   N N   . LEU A 1 20  ? -25.36100 14.05500  -2.61700  1.000 32.70360  ? 20  LEU A N   1 
ATOM   92   C CA  . LEU A 1 20  ? -24.67500 15.30600  -2.33800  1.000 30.59453  ? 20  LEU A CA  1 
ATOM   93   C C   . LEU A 1 20  ? -24.38400 15.43900  -0.84800  1.000 30.48388  ? 20  LEU A C   1 
ATOM   94   O O   . LEU A 1 20  ? -24.40900 16.54600  -0.29700  1.000 29.21281  ? 20  LEU A O   1 
ATOM   95   C CB  . LEU A 1 20  ? -25.50100 16.49500  -2.82600  1.000 29.20484  ? 20  LEU A CB  1 
ATOM   96   C CG  . LEU A 1 20  ? -25.99900 16.59400  -4.26500  1.000 28.85045  ? 20  LEU A CG  1 
ATOM   97   C CD1 . LEU A 1 20  ? -26.85400 17.86700  -4.40900  1.000 26.23117  ? 20  LEU A CD1 1 
ATOM   98   C CD2 . LEU A 1 20  ? -24.82400 16.65200  -5.21700  1.000 32.26108  ? 20  LEU A CD2 1 
ATOM   99   N N   . LEU A 1 21  ? -24.13000 14.31400  -0.17700  1.000 31.75968  ? 21  LEU A N   1 
ATOM   100  C CA  . LEU A 1 21  ? -23.83600 14.35100  1.25000   1.000 31.95352  ? 21  LEU A CA  1 
ATOM   101  C C   . LEU A 1 21  ? -22.39800 14.76300  1.54000   1.000 28.84361  ? 21  LEU A C   1 
ATOM   102  O O   . LEU A 1 21  ? -22.09800 15.16400  2.67000   1.000 40.76160  ? 21  LEU A O   1 
ATOM   103  C CB  . LEU A 1 21  ? -24.13100 12.98900  1.89000   1.000 32.21171  ? 21  LEU A CB  1 
ATOM   104  C CG  . LEU A 1 21  ? -25.57000 12.46600  1.77900   1.000 35.49682  ? 21  LEU A CG  1 
ATOM   105  C CD1 . LEU A 1 21  ? -25.75400 11.16500  2.55300   1.000 33.52610  ? 21  LEU A CD1 1 
ATOM   106  C CD2 . LEU A 1 21  ? -26.56600 13.50400  2.25300   1.000 30.64288  ? 21  LEU A CD2 1 
ATOM   107  N N   . GLY A 1 22  ? -21.49900 14.66600  0.56900   1.000 28.04238  ? 22  GLY A N   1 
ATOM   108  C CA  . GLY A 1 22  ? -20.18600 15.26000  0.75100   1.000 31.79379  ? 22  GLY A CA  1 
ATOM   109  C C   . GLY A 1 22  ? -19.16300 14.43500  1.50400   1.000 25.88561  ? 22  GLY A C   1 
ATOM   110  O O   . GLY A 1 22  ? -18.14600 14.97900  1.94600   1.000 25.68692  ? 22  GLY A O   1 
ATOM   111  N N   . GLY A 1 23  ? -19.37000 13.13900  1.64800   1.000 24.72725  ? 23  GLY A N   1 
ATOM   112  C CA  . GLY A 1 23  ? -18.39100 12.29500  2.31100   1.000 30.48903  ? 23  GLY A CA  1 
ATOM   113  C C   . GLY A 1 23  ? -18.26400 10.94900  1.63100   1.000 30.58242  ? 23  GLY A C   1 
ATOM   114  O O   . GLY A 1 23  ? -19.20500 10.46200  0.98700   1.000 25.14840  ? 23  GLY A O   1 
ATOM   115  N N   . ILE A 1 24  ? -17.07400 10.33700  1.79500   1.000 26.29958  ? 24  ILE A N   1 
ATOM   116  C CA  . ILE A 1 24  ? -16.79900 8.97600   1.33700   1.000 27.30237  ? 24  ILE A CA  1 
ATOM   117  C C   . ILE A 1 24  ? -16.54200 8.04400   2.52000   1.000 31.72824  ? 24  ILE A C   1 
ATOM   118  O O   . ILE A 1 24  ? -16.45500 8.48100   3.67500   1.000 29.94875  ? 24  ILE A O   1 
ATOM   119  C CB  . ILE A 1 24  ? -15.59600 8.91700   0.38200   1.000 26.30290  ? 24  ILE A CB  1 
ATOM   120  C CG1 . ILE A 1 24  ? -14.32700 9.36100   1.10300   1.000 28.68601  ? 24  ILE A CG1 1 
ATOM   121  C CG2 . ILE A 1 24  ? -15.82000 9.74700   -0.86300  1.000 29.25157  ? 24  ILE A CG2 1 
ATOM   122  C CD1 . ILE A 1 24  ? -13.08400 8.73600   0.51400   1.000 23.27065  ? 24  ILE A CD1 1 
ATOM   123  N N   . GLN A 1 25  ? -16.36700 6.75500   2.22200   1.000 31.85761  ? 25  GLN A N   1 
ATOM   124  C CA  . GLN A 1 25  ? -16.08300 5.74400   3.23000   1.000 28.99084  ? 25  GLN A CA  1 
ATOM   125  C C   . GLN A 1 25  ? -14.57500 5.62100   3.44400   1.000 30.67238  ? 25  GLN A C   1 
ATOM   126  O O   . GLN A 1 25  ? -13.77800 5.79200   2.51900   1.000 31.66348  ? 25  GLN A O   1 
ATOM   127  C CB  . GLN A 1 25  ? -16.68800 4.39900   2.81900   1.000 26.64557  ? 25  GLN A CB  1 
ATOM   128  C CG  . GLN A 1 25  ? -18.22000 4.39800   2.80800   1.000 25.90096  ? 25  GLN A CG  1 
ATOM   129  C CD  . GLN A 1 25  ? -18.80400 3.08100   2.33100   1.000 34.56746  ? 25  GLN A CD  1 
ATOM   130  O OE1 . GLN A 1 25  ? -18.43500 2.00800   2.83700   1.000 33.46473  ? 25  GLN A OE1 1 
ATOM   131  N NE2 . GLN A 1 25  ? -19.72500 3.14700   1.34900   1.000 28.72418  ? 25  GLN A NE2 1 
ATOM   132  N N   . SER A 1 26  ? -14.19100 5.28400   4.67300   1.000 27.92081  ? 26  SER A N   1 
ATOM   133  C CA  . SER A 1 26  ? -12.83500 5.55500   5.14600   1.000 27.97646  ? 26  SER A CA  1 
ATOM   134  C C   . SER A 1 26  ? -11.78100 4.62500   4.56900   1.000 31.97031  ? 26  SER A C   1 
ATOM   135  O O   . SER A 1 26  ? -10.58700 4.96100   4.61400   1.000 34.39488  ? 26  SER A O   1 
ATOM   136  C CB  . SER A 1 26  ? -12.80200 5.46600   6.66400   1.000 38.13152  ? 26  SER A CB  1 
ATOM   137  O OG  . SER A 1 26  ? -13.50600 4.31200   7.08600   1.000 40.81833  ? 26  SER A OG  1 
ATOM   138  N N   . HIS A 1 27  ? -12.17900 3.47000   4.04800   1.000 31.34704  ? 27  HIS A N   1 
ATOM   139  C CA  . HIS A 1 27  ? -11.24000 2.52500   3.46300   1.000 32.83821  ? 27  HIS A CA  1 
ATOM   140  C C   . HIS A 1 27  ? -10.77200 2.91100   2.06900   1.000 33.74382  ? 27  HIS A C   1 
ATOM   141  O O   . HIS A 1 27  ? -9.98000  2.16400   1.48400   1.000 38.34634  ? 27  HIS A O   1 
ATOM   142  C CB  . HIS A 1 27  ? -11.87000 1.14200   3.39200   1.000 34.75731  ? 27  HIS A CB  1 
ATOM   143  C CG  . HIS A 1 27  ? -13.13400 1.10200   2.59100   1.000 27.45496  ? 27  HIS A CG  1 
ATOM   144  N ND1 . HIS A 1 27  ? -14.38000 1.28100   3.15900   1.000 30.55213  ? 27  HIS A ND1 1 
ATOM   145  C CD2 . HIS A 1 27  ? -13.34700 0.89000   1.27100   1.000 29.71479  ? 27  HIS A CD2 1 
ATOM   146  C CE1 . HIS A 1 27  ? -15.30700 1.17000   2.22100   1.000 34.22867  ? 27  HIS A CE1 1 
ATOM   147  N NE2 . HIS A 1 27  ? -14.70700 0.93100   1.06600   1.000 33.56576  ? 27  HIS A NE2 1 
ATOM   148  N N   . GLY A 1 28  ? -11.23600 4.03500   1.51100   1.000 30.85886  ? 28  GLY A N   1 
ATOM   149  C CA  . GLY A 1 28  ? -10.76500 4.47600   0.21400   1.000 27.64120  ? 28  GLY A CA  1 
ATOM   150  C C   . GLY A 1 28  ? -10.47000 5.96500   0.20800   1.000 23.63508  ? 28  GLY A C   1 
ATOM   151  O O   . GLY A 1 28  ? -10.79900 6.69700   1.14400   1.000 27.41400  ? 28  GLY A O   1 
ATOM   152  N N   . VAL A 1 29  ? -9.84800  6.39900   -0.87700  1.000 23.20417  ? 29  VAL A N   1 
ATOM   153  C CA  . VAL A 1 29  ? -9.45600  7.78500   -1.08500  1.000 28.52167  ? 29  VAL A CA  1 
ATOM   154  C C   . VAL A 1 29  ? -10.00100 8.22300   -2.43900  1.000 27.55893  ? 29  VAL A C   1 
ATOM   155  O O   . VAL A 1 29  ? -9.94900  7.45400   -3.40500  1.000 28.54724  ? 29  VAL A O   1 
ATOM   156  C CB  . VAL A 1 29  ? -7.91300  7.93800   -1.01800  1.000 29.21448  ? 29  VAL A CB  1 
ATOM   157  C CG1 . VAL A 1 29  ? -7.47700  9.26000   -1.54900  1.000 25.20995  ? 29  VAL A CG1 1 
ATOM   158  C CG2 . VAL A 1 29  ? -7.41400  7.75800   0.42200   1.000 31.06903  ? 29  VAL A CG2 1 
ATOM   159  N N   . LEU A 1 30  ? -10.52600 9.45200   -2.50900  1.000 22.08216  ? 30  LEU A N   1 
ATOM   160  C CA  . LEU A 1 30  ? -11.06500 10.02100  -3.73900  1.000 25.00003  ? 30  LEU A CA  1 
ATOM   161  C C   . LEU A 1 30  ? -10.34500 11.31800  -4.06500  1.000 25.27302  ? 30  LEU A C   1 
ATOM   162  O O   . LEU A 1 30  ? -10.05200 12.10900  -3.16400  1.000 26.32053  ? 30  LEU A O   1 
ATOM   163  C CB  . LEU A 1 30  ? -12.57900 10.30500  -3.62000  1.000 23.99304  ? 30  LEU A CB  1 
ATOM   164  C CG  . LEU A 1 30  ? -13.34900 10.98300  -4.76000  1.000 26.65522  ? 30  LEU A CG  1 
ATOM   165  C CD1 . LEU A 1 30  ? -14.82500 10.56700  -4.73200  1.000 21.86008  ? 30  LEU A CD1 1 
ATOM   166  C CD2 . LEU A 1 30  ? -13.24600 12.50700  -4.72500  1.000 23.97109  ? 30  LEU A CD2 1 
ATOM   167  N N   . LEU A 1 31  ? -10.10100 11.53600  -5.36700  1.000 24.47110  ? 31  LEU A N   1 
ATOM   168  C CA  . LEU A 1 31  ? -9.42800  12.70800  -5.91300  1.000 27.60306  ? 31  LEU A CA  1 
ATOM   169  C C   . LEU A 1 31  ? -10.09900 13.10500  -7.21200  1.000 31.97623  ? 31  LEU A C   1 
ATOM   170  O O   . LEU A 1 31  ? -10.35200 12.24800  -8.06000  1.000 30.58549  ? 31  LEU A O   1 
ATOM   171  C CB  . LEU A 1 31  ? -7.95000  12.46500  -6.21700  1.000 27.42036  ? 31  LEU A CB  1 
ATOM   172  C CG  . LEU A 1 31  ? -7.06200  12.16300  -5.02200  1.000 33.62722  ? 31  LEU A CG  1 
ATOM   173  C CD1 . LEU A 1 31  ? -7.05600  10.67500  -4.71900  1.000 32.47672  ? 31  LEU A CD1 1 
ATOM   174  C CD2 . LEU A 1 31  ? -5.67000  12.67900  -5.28100  1.000 40.77009  ? 31  LEU A CD2 1 
ATOM   175  N N   . ALA A 1 32  ? -10.35000 14.40600  -7.37700  1.000 32.85222  ? 32  ALA A N   1 
ATOM   176  C CA  . ALA A 1 32  ? -11.02400 14.93700  -8.55200  1.000 31.95034  ? 32  ALA A CA  1 
ATOM   177  C C   . ALA A 1 32  ? -10.16000 16.00500  -9.19400  1.000 36.03883  ? 32  ALA A C   1 
ATOM   178  O O   . ALA A 1 32  ? -9.79700  16.98700  -8.54000  1.000 38.89403  ? 32  ALA A O   1 
ATOM   179  C CB  . ALA A 1 32  ? -12.39700 15.52600  -8.20500  1.000 36.51792  ? 32  ALA A CB  1 
ATOM   180  N N   . PHE A 1 33  ? -9.87200  15.82200  -10.48200 1.000 40.98658  ? 33  PHE A N   1 
ATOM   181  C CA  . PHE A 1 33  ? -9.04400  16.71300  -11.27800 1.000 35.54195  ? 33  PHE A CA  1 
ATOM   182  C C   . PHE A 1 33  ? -9.88100  17.44900  -12.30900 1.000 37.38488  ? 33  PHE A C   1 
ATOM   183  O O   . PHE A 1 33  ? -10.81700 16.87400  -12.88500 1.000 36.49201  ? 33  PHE A O   1 
ATOM   184  C CB  . PHE A 1 33  ? -7.95800  15.92300  -11.99800 1.000 40.64841  ? 33  PHE A CB  1 
ATOM   185  C CG  . PHE A 1 33  ? -7.16800  15.05500  -11.08300 1.000 45.58282  ? 33  PHE A CG  1 
ATOM   186  C CD1 . PHE A 1 33  ? -6.15800  15.60900  -10.28900 1.000 42.96971  ? 33  PHE A CD1 1 
ATOM   187  C CD2 . PHE A 1 33  ? -7.45000  13.69700  -10.98300 1.000 38.00635  ? 33  PHE A CD2 1 
ATOM   188  C CE1 . PHE A 1 33  ? -5.42100  14.83100  -9.43200  1.000 40.01225  ? 33  PHE A CE1 1 
ATOM   189  C CE2 . PHE A 1 33  ? -6.72300  12.90500  -10.12300 1.000 41.37821  ? 33  PHE A CE2 1 
ATOM   190  C CZ  . PHE A 1 33  ? -5.69700  13.47400  -9.34300  1.000 45.64759  ? 33  PHE A CZ  1 
ATOM   191  N N   . ARG A 1 34  ? -9.50200  18.70500  -12.57100 1.000 39.31183  ? 34  ARG A N   1 
ATOM   192  C CA  . ARG A 1 34  ? -10.17000 19.56600  -13.54000 1.000 38.90054  ? 34  ARG A CA  1 
ATOM   193  C C   . ARG A 1 34  ? -9.19800  19.99700  -14.62300 1.000 44.20059  ? 34  ARG A C   1 
ATOM   194  O O   . ARG A 1 34  ? -8.11800  20.51900  -14.32000 1.000 43.20901  ? 34  ARG A O   1 
ATOM   195  C CB  . ARG A 1 34  ? -10.74900 20.82100  -12.88600 1.000 38.51437  ? 34  ARG A CB  1 
ATOM   196  C CG  . ARG A 1 34  ? -11.29600 21.80100  -13.91100 1.000 44.44671  ? 34  ARG A CG  1 
ATOM   197  C CD  . ARG A 1 34  ? -12.08800 22.95200  -13.29700 1.000 47.22622  ? 34  ARG A CD  1 
ATOM   198  N NE  . ARG A 1 34  ? -13.15700 22.52000  -12.39400 1.000 56.27917  ? 34  ARG A NE  1 
ATOM   199  C CZ  . ARG A 1 34  ? -14.37100 22.11900  -12.77300 1.000 57.38161  ? 34  ARG A CZ  1 
ATOM   200  N NH1 . ARG A 1 34  ? -14.68900 21.97500  -14.05200 1.000 54.27940  ? 34  ARG A NH1 1 
ATOM   201  N NH2 . ARG A 1 34  ? -15.28800 21.84700  -11.84300 1.000 51.48595  ? 34  ARG A NH2 1 
ATOM   202  N N   . GLY A 1 35  ? -9.58900  19.80600  -15.87800 1.000 41.38199  ? 35  GLY A N   1 
ATOM   203  C CA  . GLY A 1 35  ? -9.01600  20.57700  -16.95200 1.000 45.24378  ? 35  GLY A CA  1 
ATOM   204  C C   . GLY A 1 35  ? -7.72300  20.01800  -17.49500 1.000 45.23648  ? 35  GLY A C   1 
ATOM   205  O O   . GLY A 1 35  ? -7.15000  19.06900  -16.95000 1.000 39.69651  ? 35  GLY A O   1 
ATOM   206  N N   . PRO A 1 36  ? -7.23300  20.62600  -18.58400 1.000 46.08760  ? 36  PRO A N   1 
ATOM   207  C CA  . PRO A 1 36  ? -6.09500  20.04300  -19.31600 1.000 45.29457  ? 36  PRO A CA  1 
ATOM   208  C C   . PRO A 1 36  ? -4.89000  19.75500  -18.44100 1.000 48.19525  ? 36  PRO A C   1 
ATOM   209  O O   . PRO A 1 36  ? -4.22300  18.73300  -18.64600 1.000 51.54522  ? 36  PRO A O   1 
ATOM   210  C CB  . PRO A 1 36  ? -5.78000  21.11200  -20.37400 1.000 46.24016  ? 36  PRO A CB  1 
ATOM   211  C CG  . PRO A 1 36  ? -7.04600  21.90400  -20.52500 1.000 45.55120  ? 36  PRO A CG  1 
ATOM   212  C CD  . PRO A 1 36  ? -7.67600  21.90600  -19.16900 1.000 48.39575  ? 36  PRO A CD  1 
ATOM   213  N N   . ASP A 1 37  ? -4.59900  20.62500  -17.46300 1.000 48.44064  ? 37  ASP A N   1 
ATOM   214  C CA  . ASP A 1 37  ? -3.50400  20.42400  -16.51800 1.000 42.53244  ? 37  ASP A CA  1 
ATOM   215  C C   . ASP A 1 37  ? -3.80800  19.36600  -15.47100 1.000 41.90803  ? 37  ASP A C   1 
ATOM   216  O O   . ASP A 1 37  ? -2.95500  19.13200  -14.59000 1.000 40.14128  ? 37  ASP A O   1 
ATOM   217  C CB  . ASP A 1 37  ? -3.15300  21.73700  -15.81300 1.000 38.70667  ? 37  ASP A CB  1 
ATOM   218  C CG  . ASP A 1 37  ? -2.41400  22.70600  -16.71300 1.000 50.79397  ? 37  ASP A CG  1 
ATOM   219  O OD1 . ASP A 1 37  ? -1.35000  22.33100  -17.25300 1.000 52.25471  ? 37  ASP A OD1 1 
ATOM   220  O OD2 . ASP A 1 37  ? -2.89800  23.84700  -16.88700 1.000 64.73411  ? 37  ASP A OD2 1 
ATOM   221  N N   . ARG A 1 38  ? -4.96600  18.71800  -15.55200 1.000 34.87211  ? 38  ARG A N   1 
ATOM   222  C CA  . ARG A 1 38  ? -5.44400  17.81100  -14.51300 1.000 37.32307  ? 38  ARG A CA  1 
ATOM   223  C C   . ARG A 1 38  ? -5.13600  18.36900  -13.12300 1.000 39.04234  ? 38  ARG A C   1 
ATOM   224  O O   . ARG A 1 38  ? -4.49100  17.73100  -12.29900 1.000 44.39042  ? 38  ARG A O   1 
ATOM   225  C CB  . ARG A 1 38  ? -4.84700  16.41300  -14.66700 1.000 37.29572  ? 38  ARG A CB  1 
ATOM   226  C CG  . ARG A 1 38  ? -4.65300  15.91700  -16.08100 1.000 39.93520  ? 38  ARG A CG  1 
ATOM   227  C CD  . ARG A 1 38  ? -5.84100  15.10200  -16.55000 1.000 44.10559  ? 38  ARG A CD  1 
ATOM   228  N NE  . ARG A 1 38  ? -7.02900  15.94700  -16.63000 1.000 57.31497  ? 38  ARG A NE  1 
ATOM   229  C CZ  . ARG A 1 38  ? -8.24100  15.53600  -16.98700 1.000 56.98331  ? 38  ARG A CZ  1 
ATOM   230  N NH1 . ARG A 1 38  ? -8.47400  14.27300  -17.32500 1.000 50.22786  ? 38  ARG A NH1 1 
ATOM   231  N NH2 . ARG A 1 38  ? -9.24500  16.41200  -16.99300 1.000 47.63458  ? 38  ARG A NH2 1 
ATOM   232  N N   . LEU A 1 39  ? -5.57700  19.60100  -12.87800 1.000 38.69666  ? 39  LEU A N   1 
ATOM   233  C CA  . LEU A 1 39  ? -5.37100  20.20000  -11.56600 1.000 36.58410  ? 39  LEU A CA  1 
ATOM   234  C C   . LEU A 1 39  ? -6.30900  19.57600  -10.54800 1.000 37.95698  ? 39  LEU A C   1 
ATOM   235  O O   . LEU A 1 39  ? -7.44600  19.21800  -10.86200 1.000 39.52784  ? 39  LEU A O   1 
ATOM   236  C CB  . LEU A 1 39  ? -5.61400  21.71100  -11.60300 1.000 40.34183  ? 39  LEU A CB  1 
ATOM   237  C CG  . LEU A 1 39  ? -4.71100  22.53700  -12.51200 1.000 37.17508  ? 39  LEU A CG  1 
ATOM   238  C CD1 . LEU A 1 39  ? -5.10300  24.00900  -12.46100 1.000 32.62856  ? 39  LEU A CD1 1 
ATOM   239  C CD2 . LEU A 1 39  ? -3.26500  22.31500  -12.08700 1.000 44.05036  ? 39  LEU A CD2 1 
ATOM   240  N N   . LEU A 1 40  ? -5.82900  19.46400  -9.31400  1.000 35.95893  ? 40  LEU A N   1 
ATOM   241  C CA  . LEU A 1 40  ? -6.59600  18.83200  -8.24900  1.000 38.07837  ? 40  LEU A CA  1 
ATOM   242  C C   . LEU A 1 40  ? -7.59900  19.82500  -7.67200  1.000 40.19801  ? 40  LEU A C   1 
ATOM   243  O O   . LEU A 1 40  ? -7.21500  20.85500  -7.10200  1.000 40.34968  ? 40  LEU A O   1 
ATOM   244  C CB  . LEU A 1 40  ? -5.66700  18.31400  -7.15900  1.000 39.44050  ? 40  LEU A CB  1 
ATOM   245  C CG  . LEU A 1 40  ? -6.45400  17.56400  -6.08800  1.000 44.27993  ? 40  LEU A CG  1 
ATOM   246  C CD1 . LEU A 1 40  ? -6.63900  16.09000  -6.47800  1.000 41.73295  ? 40  LEU A CD1 1 
ATOM   247  C CD2 . LEU A 1 40  ? -5.79300  17.70200  -4.73100  1.000 44.04160  ? 40  LEU A CD2 1 
ATOM   248  N N   . GLU A 1 41  ? -8.88700  19.51500  -7.81400  1.000 38.57465  ? 41  GLU A N   1 
ATOM   249  C CA  . GLU A 1 41  ? -9.94700  20.41700  -7.39100  1.000 33.67606  ? 41  GLU A CA  1 
ATOM   250  C C   . GLU A 1 41  ? -10.64300 19.97600  -6.11200  1.000 34.30109  ? 41  GLU A C   1 
ATOM   251  O O   . GLU A 1 41  ? -11.02700 20.81800  -5.29800  1.000 39.73470  ? 41  GLU A O   1 
ATOM   252  C CB  . GLU A 1 41  ? -10.98500 20.54700  -8.50900  1.000 37.18514  ? 41  GLU A CB  1 
ATOM   253  C CG  . GLU A 1 41  ? -12.12400 21.46600  -8.17300  1.000 41.63352  ? 41  GLU A CG  1 
ATOM   254  C CD  . GLU A 1 41  ? -12.18300 22.65500  -9.08500  1.000 44.41759  ? 41  GLU A CD  1 
ATOM   255  O OE1 . GLU A 1 41  ? -11.54600 22.62600  -10.16300 1.000 44.25408  ? 41  GLU A OE1 1 
ATOM   256  O OE2 . GLU A 1 41  ? -12.87700 23.62100  -8.71900  1.000 52.20513  ? 41  GLU A OE2 1 
ATOM   257  N N   . VAL A 1 42  ? -10.82000 18.67600  -5.92300  1.000 37.40727  ? 42  VAL A N   1 
ATOM   258  C CA  . VAL A 1 42  ? -11.50300 18.10800  -4.77000  1.000 33.85152  ? 42  VAL A CA  1 
ATOM   259  C C   . VAL A 1 42  ? -10.73500 16.86400  -4.36900  1.000 31.72666  ? 42  VAL A C   1 
ATOM   260  O O   . VAL A 1 42  ? -10.29700 16.09000  -5.23100  1.000 33.20504  ? 42  VAL A O   1 
ATOM   261  C CB  . VAL A 1 42  ? -12.97900 17.76300  -5.07600  1.000 30.07246  ? 42  VAL A CB  1 
ATOM   262  C CG1 . VAL A 1 42  ? -13.72800 17.49600  -3.77900  1.000 29.04231  ? 42  VAL A CG1 1 
ATOM   263  C CG2 . VAL A 1 42  ? -13.63800 18.89300  -5.85600  1.000 22.23447  ? 42  VAL A CG2 1 
ATOM   264  N N   . VAL A 1 43  ? -10.55400 16.68600  -3.06500  1.000 30.11216  ? 43  VAL A N   1 
ATOM   265  C CA  . VAL A 1 43  ? -9.83900  15.54200  -2.52100  1.000 28.91365  ? 43  VAL A CA  1 
ATOM   266  C C   . VAL A 1 43  ? -10.39900 15.24000  -1.13300  1.000 27.28072  ? 43  VAL A C   1 
ATOM   267  O O   . VAL A 1 43  ? -10.75500 16.15000  -0.37500  1.000 29.84193  ? 43  VAL A O   1 
ATOM   268  C CB  . VAL A 1 43  ? -8.31800  15.81600  -2.48700  1.000 31.75056  ? 43  VAL A CB  1 
ATOM   269  C CG1 . VAL A 1 43  ? -7.99300  16.92000  -1.49400  1.000 26.94878  ? 43  VAL A CG1 1 
ATOM   270  C CG2 . VAL A 1 43  ? -7.58000  14.54200  -2.12900  1.000 33.53459  ? 43  VAL A CG2 1 
ATOM   271  N N   . SER A 1 44  ? -10.49200 13.95800  -0.79900  1.000 28.21650  ? 44  SER A N   1 
ATOM   272  C CA  . SER A 1 44  ? -11.00500 13.58800  0.51200   1.000 28.07783  ? 44  SER A CA  1 
ATOM   273  C C   . SER A 1 44  ? -9.97600  13.88700  1.58700   1.000 28.84576  ? 44  SER A C   1 
ATOM   274  O O   . SER A 1 44  ? -8.76700  13.88200  1.34300   1.000 29.80329  ? 44  SER A O   1 
ATOM   275  C CB  . SER A 1 44  ? -11.37300 12.11300  0.55800   1.000 26.82556  ? 44  SER A CB  1 
ATOM   276  O OG  . SER A 1 44  ? -10.23500 11.32000  0.32000   1.000 27.66850  ? 44  SER A OG  1 
ATOM   277  N N   . ALA A 1 45  ? -10.47000 14.11000  2.80500   1.000 28.70898  ? 45  ALA A N   1 
ATOM   278  C CA  . ALA A 1 45  ? -9.60700  14.60500  3.86800   1.000 28.63086  ? 45  ALA A CA  1 
ATOM   279  C C   . ALA A 1 45  ? -8.65400  13.54000  4.38900   1.000 32.30940  ? 45  ALA A C   1 
ATOM   280  O O   . ALA A 1 45  ? -7.68100  13.88200  5.06400   1.000 37.22846  ? 45  ALA A O   1 
ATOM   281  C CB  . ALA A 1 45  ? -10.45500 15.17200  5.00400   1.000 22.82969  ? 45  ALA A CB  1 
ATOM   282  N N   . ASN A 1 46  ? -8.90000  12.26400  4.09200   1.000 34.73397  ? 46  ASN A N   1 
ATOM   283  C CA  . ASN A 1 46  ? -8.01600  11.18700  4.52500   1.000 35.38978  ? 46  ASN A CA  1 
ATOM   284  C C   . ASN A 1 46  ? -6.91300  10.89900  3.52000   1.000 38.71868  ? 46  ASN A C   1 
ATOM   285  O O   . ASN A 1 46  ? -6.20800  9.89500   3.65700   1.000 39.44999  ? 46  ASN A O   1 
ATOM   286  C CB  . ASN A 1 46  ? -8.82000  9.90700   4.76800   1.000 32.73484  ? 46  ASN A CB  1 
ATOM   287  C CG  . ASN A 1 46  ? -9.41300  9.34300   3.49000   1.000 29.40667  ? 46  ASN A CG  1 
ATOM   288  O OD1 . ASN A 1 46  ? -9.59000  10.06000  2.49700   1.000 29.32246  ? 46  ASN A OD1 1 
ATOM   289  N ND2 . ASN A 1 46  ? -9.71800  8.05300   3.50300   1.000 30.85525  ? 46  ASN A ND2 1 
ATOM   290  N N   . ALA A 1 47  ? -6.76700  11.74300  2.50000   1.000 38.39055  ? 47  ALA A N   1 
ATOM   291  C CA  . ALA A 1 47  ? -5.91600  11.38900  1.37800   1.000 37.90828  ? 47  ALA A CA  1 
ATOM   292  C C   . ALA A 1 47  ? -4.44400  11.31800  1.76300   1.000 45.67830  ? 47  ALA A C   1 
ATOM   293  O O   . ALA A 1 47  ? -3.65300  10.71800  1.02700   1.000 44.65654  ? 47  ALA A O   1 
ATOM   294  C CB  . ALA A 1 47  ? -6.13800  12.38800  0.24600   1.000 33.73065  ? 47  ALA A CB  1 
ATOM   295  N N   . GLN A 1 48  ? -4.05900  11.90100  2.90200   1.000 49.74624  ? 48  GLN A N   1 
ATOM   296  C CA  . GLN A 1 48  ? -2.68300  11.76200  3.36900   1.000 50.98603  ? 48  GLN A CA  1 
ATOM   297  C C   . GLN A 1 48  ? -2.33300  10.31100  3.68400   1.000 45.24096  ? 48  GLN A C   1 
ATOM   298  O O   . GLN A 1 48  ? -1.18300  9.90700   3.51500   1.000 49.08714  ? 48  GLN A O   1 
ATOM   299  C CB  . GLN A 1 48  ? -2.44600  12.64400  4.59500   1.000 51.86428  ? 48  GLN A CB  1 
ATOM   300  C CG  . GLN A 1 48  ? -0.96400  12.75500  4.93900   1.000 56.38534  ? 48  GLN A CG  1 
ATOM   301  C CD  . GLN A 1 48  ? -0.63200  13.84600  5.95300   1.000 60.49851  ? 48  GLN A CD  1 
ATOM   302  O OE1 . GLN A 1 48  ? -1.43300  14.75500  6.22500   1.000 56.28415  ? 48  GLN A OE1 1 
ATOM   303  N NE2 . GLN A 1 48  ? 0.57200   13.76200  6.51100   1.000 62.15517  ? 48  GLN A NE2 1 
ATOM   304  N N   . ALA A 1 49  ? -3.31300  9.50600   4.10100   1.000 52.68513  ? 49  ALA A N   1 
ATOM   305  C CA  . ALA A 1 49  ? -3.09300  8.09400   4.42100   1.000 52.21355  ? 49  ALA A CA  1 
ATOM   306  C C   . ALA A 1 49  ? -2.59400  7.27700   3.24000   1.000 57.24341  ? 49  ALA A C   1 
ATOM   307  O O   . ALA A 1 49  ? -2.26100  6.10000   3.42000   1.000 59.26466  ? 49  ALA A O   1 
ATOM   308  C CB  . ALA A 1 49  ? -4.38700  7.45100   4.93400   1.000 49.51208  ? 49  ALA A CB  1 
ATOM   309  N N   . LEU A 1 50  ? -2.55100  7.85300   2.04200   1.000 57.70202  ? 50  LEU A N   1 
ATOM   310  C CA  . LEU A 1 50  ? -2.09800  7.15600   0.85100   1.000 52.13807  ? 50  LEU A CA  1 
ATOM   311  C C   . LEU A 1 50  ? -1.18400  8.01400   -0.00700  1.000 54.58005  ? 50  LEU A C   1 
ATOM   312  O O   . LEU A 1 50  ? -0.74900  7.56100   -1.06900  1.000 58.03288  ? 50  LEU A O   1 
ATOM   313  C CB  . LEU A 1 50  ? -3.29800  6.71300   -0.00100  1.000 50.36215  ? 50  LEU A CB  1 
ATOM   314  C CG  . LEU A 1 50  ? -3.92800  5.31500   0.11100   1.000 55.85131  ? 50  LEU A CG  1 
ATOM   315  C CD1 . LEU A 1 50  ? -2.87100  4.26100   -0.13800  1.000 57.87049  ? 50  LEU A CD1 1 
ATOM   316  C CD2 . LEU A 1 50  ? -4.66300  5.05900   1.43700   1.000 56.61035  ? 50  LEU A CD2 1 
ATOM   317  N N   . LEU A 1 51  ? -0.92300  9.25300   0.39000   1.000 58.76320  ? 51  LEU A N   1 
ATOM   318  C CA  . LEU A 1 51  ? -0.16200  10.17800  -0.43700  1.000 61.57276  ? 51  LEU A CA  1 
ATOM   319  C C   . LEU A 1 51  ? 0.99700   10.84400  0.29300   1.000 65.64469  ? 51  LEU A C   1 
ATOM   320  O O   . LEU A 1 51  ? 1.79900   11.52800  -0.35800  1.000 69.94458  ? 51  LEU A O   1 
ATOM   321  C CB  . LEU A 1 51  ? -1.08500  11.26700  -1.01500  1.000 57.66140  ? 51  LEU A CB  1 
ATOM   322  C CG  . LEU A 1 51  ? -1.92100  10.96300  -2.27200  1.000 59.92358  ? 51  LEU A CG  1 
ATOM   323  C CD1 . LEU A 1 51  ? -2.92800  9.83300   -2.06900  1.000 56.55986  ? 51  LEU A CD1 1 
ATOM   324  C CD2 . LEU A 1 51  ? -2.64400  12.21700  -2.76600  1.000 53.93321  ? 51  LEU A CD2 1 
ATOM   325  N N   . GLY A 1 52  ? 1.11600   10.67400  1.60700   1.000 61.25569  ? 52  GLY A N   1 
ATOM   326  C CA  . GLY A 1 52  ? 2.22700   11.25700  2.32900   1.000 61.59595  ? 52  GLY A CA  1 
ATOM   327  C C   . GLY A 1 52  ? 1.97700   12.68600  2.76100   1.000 61.25885  ? 52  GLY A C   1 
ATOM   328  O O   . GLY A 1 52  ? 2.08700   12.99500  3.95400   1.000 69.47505  ? 52  GLY A O   1 
ATOM   329  N N   . ARG A 1 53  ? 1.61000   13.58800  1.78700   1.000 57.30226  ? 53  ARG A N   1 
ATOM   330  C CA  . ARG A 1 53  ? 1.48400   15.02400  2.02000   1.000 63.35408  ? 53  ARG A CA  1 
ATOM   331  C C   . ARG A 1 53  ? 0.09300   15.40500  2.54100   1.000 58.52268  ? 53  ARG A C   1 
ATOM   332  O O   . ARG A 1 53  ? -0.89900  14.72100  2.26100   1.000 55.59624  ? 53  ARG A O   1 
ATOM   333  C CB  . ARG A 1 53  ? 1.78000   15.78900  0.73000   1.000 66.67616  ? 53  ARG A CB  1 
ATOM   334  C CG  . ARG A 1 53  ? 3.20500   15.58300  0.21500   1.000 73.13761  ? 53  ARG A CG  1 
ATOM   335  C CD  . ARG A 1 53  ? 3.40900   16.10200  -1.21100  1.000 78.39844  ? 53  ARG A CD  1 
ATOM   336  N NE  . ARG A 1 53  ? 4.57100   16.98300  -1.32100  1.000 80.71497  ? 53  ARG A NE  1 
ATOM   337  C CZ  . ARG A 1 53  ? 4.54100   18.21100  -1.82400  1.000 82.96163  ? 53  ARG A CZ  1 
ATOM   338  N NH1 . ARG A 1 53  ? 3.42500   18.73300  -2.31200  1.000 79.76869  ? 53  ARG A NH1 1 
ATOM   339  N NH2 . ARG A 1 53  ? 5.65900   18.93300  -1.84500  1.000 83.01984  ? 53  ARG A NH2 1 
ATOM   340  N N   . PRO A 1 54  ? 0.00200   16.47900  3.32300   1.000 56.23862  ? 54  PRO A N   1 
ATOM   341  C CA  . PRO A 1 54  ? -1.31300  16.98500  3.76300   1.000 60.10288  ? 54  PRO A CA  1 
ATOM   342  C C   . PRO A 1 54  ? -2.20300  17.31900  2.57900   1.000 57.96258  ? 54  PRO A C   1 
ATOM   343  O O   . PRO A 1 54  ? -1.79900  18.09800  1.70000   1.000 52.95821  ? 54  PRO A O   1 
ATOM   344  C CB  . PRO A 1 54  ? -0.95200  18.24900  4.56100   1.000 55.31210  ? 54  PRO A CB  1 
ATOM   345  C CG  . PRO A 1 54  ? 0.42100   17.95900  5.09100   1.000 55.71602  ? 54  PRO A CG  1 
ATOM   346  C CD  . PRO A 1 54  ? 1.11500   17.12300  4.04300   1.000 57.02068  ? 54  PRO A CD  1 
ATOM   347  N N   . PRO A 1 55  ? -3.42400  16.74800  2.52600   1.000 57.99573  ? 55  PRO A N   1 
ATOM   348  C CA  . PRO A 1 55  ? -4.31500  16.99300  1.37500   1.000 60.24841  ? 55  PRO A CA  1 
ATOM   349  C C   . PRO A 1 55  ? -4.46300  18.45500  0.97600   1.000 56.32164  ? 55  PRO A C   1 
ATOM   350  O O   . PRO A 1 55  ? -4.43400  18.75300  -0.22500  1.000 54.30200  ? 55  PRO A O   1 
ATOM   351  C CB  . PRO A 1 55  ? -5.66000  16.39600  1.83500   1.000 54.19430  ? 55  PRO A CB  1 
ATOM   352  C CG  . PRO A 1 55  ? -5.41400  15.77600  3.20300   1.000 51.12466  ? 55  PRO A CG  1 
ATOM   353  C CD  . PRO A 1 55  ? -3.93300  15.65400  3.36900   1.000 58.05474  ? 55  PRO A CD  1 
ATOM   354  N N   . GLU A 1 56  ? -4.60000  19.37800  1.93400   1.000 56.97220  ? 56  GLU A N   1 
ATOM   355  C CA  . GLU A 1 56  ? -4.85300  20.77500  1.57300   1.000 58.89756  ? 56  GLU A CA  1 
ATOM   356  C C   . GLU A 1 56  ? -3.70000  21.37800  0.77400   1.000 52.89940  ? 56  GLU A C   1 
ATOM   357  O O   . GLU A 1 56  ? -3.92600  22.24100  -0.08300  1.000 51.82699  ? 56  GLU A O   1 
ATOM   358  C CB  . GLU A 1 56  ? -5.12400  21.61700  2.82600   1.000 58.43528  ? 56  GLU A CB  1 
ATOM   359  C CG  . GLU A 1 56  ? -6.08000  20.98900  3.84500   1.000 61.19033  ? 56  GLU A CG  1 
ATOM   360  C CD  . GLU A 1 56  ? -5.36200  20.08500  4.84600   1.000 68.80635  ? 56  GLU A CD  1 
ATOM   361  O OE1 . GLU A 1 56  ? -4.35200  20.53400  5.44000   1.000 65.47249  ? 56  GLU A OE1 1 
ATOM   362  O OE2 . GLU A 1 56  ? -5.79900  18.92200  5.02600   1.000 66.23661  ? 56  GLU A OE2 1 
ATOM   363  N N   . THR A 1 57  ? -2.46200  20.94100  1.04100   1.000 57.17196  ? 57  THR A N   1 
ATOM   364  C CA  . THR A 1 57  ? -1.27900  21.37300  0.30000   1.000 50.09657  ? 57  THR A CA  1 
ATOM   365  C C   . THR A 1 57  ? -1.25600  20.84500  -1.12600  1.000 51.07151  ? 57  THR A C   1 
ATOM   366  O O   . THR A 1 57  ? -0.36400  21.21200  -1.89200  1.000 58.88527  ? 57  THR A O   1 
ATOM   367  C CB  . THR A 1 57  ? -0.00500  20.92100  1.02400   1.000 56.44161  ? 57  THR A CB  1 
ATOM   368  O OG1 . THR A 1 57  ? 0.15500   19.50600  0.87600   1.000 55.92924  ? 57  THR A OG1 1 
ATOM   369  C CG2 . THR A 1 57  ? -0.07000  21.25400  2.51400   1.000 55.14060  ? 57  THR A CG2 1 
ATOM   370  N N   . LEU A 1 58  ? -2.19600  19.97600  -1.49200  1.000 55.27891  ? 58  LEU A N   1 
ATOM   371  C CA  . LEU A 1 58  ? -2.25200  19.38500  -2.81700  1.000 53.93317  ? 58  LEU A CA  1 
ATOM   372  C C   . LEU A 1 58  ? -3.35000  19.96800  -3.69400  1.000 53.12256  ? 58  LEU A C   1 
ATOM   373  O O   . LEU A 1 58  ? -3.29700  19.79000  -4.92000  1.000 46.25739  ? 58  LEU A O   1 
ATOM   374  C CB  . LEU A 1 58  ? -2.46600  17.87000  -2.70900  1.000 54.38294  ? 58  LEU A CB  1 
ATOM   375  C CG  . LEU A 1 58  ? -1.21100  17.00200  -2.67100  1.000 60.99083  ? 58  LEU A CG  1 
ATOM   376  C CD1 . LEU A 1 58  ? -0.10800  17.66400  -1.85900  1.000 65.54088  ? 58  LEU A CD1 1 
ATOM   377  C CD2 . LEU A 1 58  ? -1.55000  15.61300  -2.12100  1.000 53.42252  ? 58  LEU A CD2 1 
ATOM   378  N N   . LEU A 1 59  ? -4.34000  20.64100  -3.09800  1.000 47.78659  ? 59  LEU A N   1 
ATOM   379  C CA  . LEU A 1 59  ? -5.39300  21.26900  -3.88300  1.000 45.93941  ? 59  LEU A CA  1 
ATOM   380  C C   . LEU A 1 59  ? -4.79000  22.30100  -4.82900  1.000 45.56445  ? 59  LEU A C   1 
ATOM   381  O O   . LEU A 1 59  ? -3.99300  23.15300  -4.41800  1.000 47.32009  ? 59  LEU A O   1 
ATOM   382  C CB  . LEU A 1 59  ? -6.43100  21.90900  -2.95700  1.000 41.90395  ? 59  LEU A CB  1 
ATOM   383  C CG  . LEU A 1 59  ? -7.52800  20.96000  -2.45400  1.000 42.60246  ? 59  LEU A CG  1 
ATOM   384  C CD1 . LEU A 1 59  ? -8.53600  21.68900  -1.60800  1.000 45.02400  ? 59  LEU A CD1 1 
ATOM   385  C CD2 . LEU A 1 59  ? -8.23700  20.29900  -3.61100  1.000 36.25265  ? 59  LEU A CD2 1 
ATOM   386  N N   . GLY A 1 60  ? -5.14200  22.19900  -6.11000  1.000 43.42992  ? 60  GLY A N   1 
ATOM   387  C CA  . GLY A 1 60  ? -4.62800  23.10200  -7.12200  1.000 40.41157  ? 60  GLY A CA  1 
ATOM   388  C C   . GLY A 1 60  ? -3.33300  22.68100  -7.79100  1.000 45.47622  ? 60  GLY A C   1 
ATOM   389  O O   . GLY A 1 60  ? -2.76700  23.46800  -8.55900  1.000 43.90950  ? 60  GLY A O   1 
ATOM   390  N N   . GLN A 1 61  ? -2.84200  21.44900  -7.53000  1.000 48.28376  ? 61  GLN A N   1 
ATOM   391  C CA  . GLN A 1 61  ? -1.62300  20.94900  -8.13500  1.000 41.78496  ? 61  GLN A CA  1 
ATOM   392  C C   . GLN A 1 61  ? -1.94300  20.02000  -9.30000  1.000 38.68139  ? 61  GLN A C   1 
ATOM   393  O O   . GLN A 1 61  ? -2.98500  19.35500  -9.30100  1.000 38.30040  ? 61  GLN A O   1 
ATOM   394  C CB  . GLN A 1 61  ? -0.78600  20.19200  -7.10200  1.000 47.11368  ? 61  GLN A CB  1 
ATOM   395  C CG  . GLN A 1 61  ? -0.38500  20.99600  -5.88400  1.000 50.47770  ? 61  GLN A CG  1 
ATOM   396  C CD  . GLN A 1 61  ? 0.86900   21.80500  -6.11900  1.000 54.97674  ? 61  GLN A CD  1 
ATOM   397  O OE1 . GLN A 1 61  ? 1.39700   21.83800  -7.23300  1.000 55.51184  ? 61  GLN A OE1 1 
ATOM   398  N NE2 . GLN A 1 61  ? 1.36000   22.46400  -5.06800  1.000 63.25084  ? 61  GLN A NE2 1 
ATOM   399  N N   . PRO A 1 62  ? -1.06200  19.98900  -10.30600 1.000 45.00434  ? 62  PRO A N   1 
ATOM   400  C CA  . PRO A 1 62  ? -1.20900  19.02200  -11.40000 1.000 39.61736  ? 62  PRO A CA  1 
ATOM   401  C C   . PRO A 1 62  ? -1.20100  17.58500  -10.89900 1.000 43.69435  ? 62  PRO A C   1 
ATOM   402  O O   . PRO A 1 62  ? -0.57100  17.25500  -9.89400  1.000 43.31396  ? 62  PRO A O   1 
ATOM   403  C CB  . PRO A 1 62  ? 0.01900   19.29700  -12.28100 1.000 41.12722  ? 62  PRO A CB  1 
ATOM   404  C CG  . PRO A 1 62  ? 0.41500   20.68800  -11.98600 1.000 43.41215  ? 62  PRO A CG  1 
ATOM   405  C CD  . PRO A 1 62  ? 0.04600   20.93300  -10.54700 1.000 53.95612  ? 62  PRO A CD  1 
ATOM   406  N N   . VAL A 1 63  ? -1.88000  16.71700  -11.64900 1.000 45.63116  ? 63  VAL A N   1 
ATOM   407  C CA  . VAL A 1 63  ? -1.94600  15.30400  -11.29200 1.000 45.45266  ? 63  VAL A CA  1 
ATOM   408  C C   . VAL A 1 63  ? -0.54900  14.70800  -11.18800 1.000 48.71543  ? 63  VAL A C   1 
ATOM   409  O O   . VAL A 1 63  ? -0.28800  13.85400  -10.33200 1.000 50.66858  ? 63  VAL A O   1 
ATOM   410  C CB  . VAL A 1 63  ? -2.81300  14.53900  -12.31100 1.000 42.04927  ? 63  VAL A CB  1 
ATOM   411  C CG1 . VAL A 1 63  ? -2.07800  14.41900  -13.63900 1.000 45.54676  ? 63  VAL A CG1 1 
ATOM   412  C CG2 . VAL A 1 63  ? -3.16700  13.16900  -11.78700 1.000 45.11736  ? 63  VAL A CG2 1 
ATOM   413  N N   . GLY A 1 64  ? 0.38000   15.16000  -12.03900 1.000 49.82916  ? 64  GLY A N   1 
ATOM   414  C CA  . GLY A 1 64  ? 1.70600   14.56000  -12.04800 1.000 49.58101  ? 64  GLY A CA  1 
ATOM   415  C C   . GLY A 1 64  ? 2.45700   14.75800  -10.74600 1.000 52.74874  ? 64  GLY A C   1 
ATOM   416  O O   . GLY A 1 64  ? 3.26900   13.91200  -10.35200 1.000 51.38463  ? 64  GLY A O   1 
ATOM   417  N N   . ARG A 1 65  ? 2.18000   15.85400  -10.04800 1.000 49.33538  ? 65  ARG A N   1 
ATOM   418  C CA  . ARG A 1 65  ? 2.89300   16.16000  -8.82100  1.000 47.70469  ? 65  ARG A CA  1 
ATOM   419  C C   . ARG A 1 65  ? 2.21600   15.62100  -7.57000  1.000 51.02782  ? 65  ARG A C   1 
ATOM   420  O O   . ARG A 1 65  ? 2.89600   15.45200  -6.55300  1.000 53.01920  ? 65  ARG A O   1 
ATOM   421  C CB  . ARG A 1 65  ? 3.08100   17.66900  -8.70700  1.000 49.14529  ? 65  ARG A CB  1 
ATOM   422  C CG  . ARG A 1 65  ? 3.87500   18.21800  -9.88300  1.000 59.07199  ? 65  ARG A CG  1 
ATOM   423  C CD  . ARG A 1 65  ? 4.92600   19.21100  -9.42000  1.000 70.50196  ? 65  ARG A CD  1 
ATOM   424  N NE  . ARG A 1 65  ? 4.30800   20.34800  -8.74900  1.000 70.86804  ? 65  ARG A NE  1 
ATOM   425  C CZ  . ARG A 1 65  ? 3.74100   21.36700  -9.38200  1.000 78.69055  ? 65  ARG A CZ  1 
ATOM   426  N NH1 . ARG A 1 65  ? 3.71900   21.43500  -10.70800 1.000 77.42221  ? 65  ARG A NH1 1 
ATOM   427  N NH2 . ARG A 1 65  ? 3.17700   22.34300  -8.67000  1.000 72.70933  ? 65  ARG A NH2 1 
ATOM   428  N N   . VAL A 1 66  ? 0.91600   15.32100  -7.62000  1.000 51.47705  ? 66  VAL A N   1 
ATOM   429  C CA  . VAL A 1 66  ? 0.19700   14.86500  -6.43100  1.000 45.51472  ? 66  VAL A CA  1 
ATOM   430  C C   . VAL A 1 66  ? 0.16400   13.34100  -6.33300  1.000 47.10591  ? 66  VAL A C   1 
ATOM   431  O O   . VAL A 1 66  ? 0.16300   12.79500  -5.22600  1.000 50.77816  ? 66  VAL A O   1 
ATOM   432  C CB  . VAL A 1 66  ? -1.23900  15.45900  -6.37500  1.000 46.76302  ? 66  VAL A CB  1 
ATOM   433  C CG1 . VAL A 1 66  ? -1.20600  16.94700  -6.26400  1.000 42.73101  ? 66  VAL A CG1 1 
ATOM   434  C CG2 . VAL A 1 66  ? -2.07800  15.06100  -7.58500  1.000 49.68654  ? 66  VAL A CG2 1 
ATOM   435  N N   . LEU A 1 67  ? 0.12300   12.61300  -7.46600  1.000 47.39024  ? 67  LEU A N   1 
ATOM   436  C CA  . LEU A 1 67  ? -0.08100  11.17200  -7.34600  1.000 47.94319  ? 67  LEU A CA  1 
ATOM   437  C C   . LEU A 1 67  ? 1.24200   10.45800  -7.09100  1.000 47.72602  ? 67  LEU A C   1 
ATOM   438  O O   . LEU A 1 67  ? 2.29000   10.88900  -7.57500  1.000 49.38737  ? 67  LEU A O   1 
ATOM   439  C CB  . LEU A 1 67  ? -0.71200  10.59100  -8.60800  1.000 43.45588  ? 67  LEU A CB  1 
ATOM   440  C CG  . LEU A 1 67  ? -2.18500  10.80600  -8.91400  1.000 45.21876  ? 67  LEU A CG  1 
ATOM   441  C CD1 . LEU A 1 67  ? -2.59500  9.93500   -10.09300 1.000 43.84334  ? 67  LEU A CD1 1 
ATOM   442  C CD2 . LEU A 1 67  ? -3.02100  10.50300  -7.70200  1.000 40.65308  ? 67  LEU A CD2 1 
ATOM   443  N N   . PRO A 1 68  ? 1.21300   9.34600   -6.35800  1.000 49.62096  ? 68  PRO A N   1 
ATOM   444  C CA  . PRO A 1 68  ? 2.41200   8.50600   -6.25000  1.000 47.51623  ? 68  PRO A CA  1 
ATOM   445  C C   . PRO A 1 68  ? 2.83600   8.00400   -7.61600  1.000 46.21232  ? 68  PRO A C   1 
ATOM   446  O O   . PRO A 1 68  ? 2.04100   7.92100   -8.55400  1.000 48.72713  ? 68  PRO A O   1 
ATOM   447  C CB  . PRO A 1 68  ? 1.97200   7.34500   -5.34700  1.000 46.20783  ? 68  PRO A CB  1 
ATOM   448  C CG  . PRO A 1 68  ? 0.74500   7.83900   -4.65000  1.000 54.00654  ? 68  PRO A CG  1 
ATOM   449  C CD  . PRO A 1 68  ? 0.08300   8.81400   -5.57700  1.000 55.57080  ? 68  PRO A CD  1 
ATOM   450  N N   . ALA A 1 69  ? 4.12400   7.66800   -7.70900  1.000 51.01036  ? 69  ALA A N   1 
ATOM   451  C CA  . ALA A 1 69  ? 4.69700   7.22100   -8.97200  1.000 45.92709  ? 69  ALA A CA  1 
ATOM   452  C C   . ALA A 1 69  ? 4.04700   5.92700   -9.45400  1.000 52.69472  ? 69  ALA A C   1 
ATOM   453  O O   . ALA A 1 69  ? 3.78000   5.77100   -10.65300 1.000 49.88113  ? 69  ALA A O   1 
ATOM   454  C CB  . ALA A 1 69  ? 6.20500   7.04400   -8.81200  1.000 48.11200  ? 69  ALA A CB  1 
ATOM   455  N N   . GLU A 1 70  ? 3.79300   4.98700   -8.52900  1.000 52.40920  ? 70  GLU A N   1 
ATOM   456  C CA  . GLU A 1 70  ? 3.11300   3.73300   -8.86700  1.000 51.23806  ? 70  GLU A CA  1 
ATOM   457  C C   . GLU A 1 70  ? 1.80700   3.97700   -9.61900  1.000 51.55065  ? 70  GLU A C   1 
ATOM   458  O O   . GLU A 1 70  ? 1.48700   3.26100   -10.57600 1.000 51.29278  ? 70  GLU A O   1 
ATOM   459  C CB  . GLU A 1 70  ? 2.82700   2.92600   -7.59500  1.000 46.59761  ? 70  GLU A CB  1 
ATOM   460  C CG  . GLU A 1 70  ? 4.04200   2.49800   -6.79300  1.000 52.01141  ? 70  GLU A CG  1 
ATOM   461  C CD  . GLU A 1 70  ? 4.58800   3.59500   -5.89800  1.000 54.77353  ? 70  GLU A CD  1 
ATOM   462  O OE1 . GLU A 1 70  ? 4.15900   4.75600   -6.05800  1.000 58.85347  ? 70  GLU A OE1 1 
ATOM   463  O OE2 . GLU A 1 70  ? 5.45300   3.29800   -5.03900  1.000 59.50397  ? 70  GLU A OE2 1 
ATOM   464  N N   . VAL A 1 71  ? 1.03000   4.97600   -9.18900  1.000 52.74411  ? 71  VAL A N   1 
ATOM   465  C CA  . VAL A 1 71  ? -0.24500  5.24500   -9.84400  1.000 49.86051  ? 71  VAL A CA  1 
ATOM   466  C C   . VAL A 1 71  ? -0.00500  5.86700   -11.20700 1.000 49.87458  ? 71  VAL A C   1 
ATOM   467  O O   . VAL A 1 71  ? -0.62600  5.47500   -12.20000 1.000 51.84197  ? 71  VAL A O   1 
ATOM   468  C CB  . VAL A 1 71  ? -1.13800  6.14000   -8.96000  1.000 49.88444  ? 71  VAL A CB  1 
ATOM   469  C CG1 . VAL A 1 71  ? -2.61200  6.02700   -9.38700  1.000 36.84255  ? 71  VAL A CG1 1 
ATOM   470  C CG2 . VAL A 1 71  ? -0.96600  5.79000   -7.48600  1.000 42.06599  ? 71  VAL A CG2 1 
ATOM   471  N N   . LEU A 1 72  ? 0.91400   6.83400   -11.27900 1.000 51.87850  ? 72  LEU A N   1 
ATOM   472  C CA  . LEU A 1 72  ? 1.19700   7.49500   -12.54900 1.000 53.46843  ? 72  LEU A CA  1 
ATOM   473  C C   . LEU A 1 72  ? 1.69200   6.50200   -13.59400 1.000 54.19320  ? 72  LEU A C   1 
ATOM   474  O O   . LEU A 1 72  ? 1.37900   6.63400   -14.78300 1.000 56.33046  ? 72  LEU A O   1 
ATOM   475  C CB  . LEU A 1 72  ? 2.21700   8.61600   -12.34400 1.000 43.74452  ? 72  LEU A CB  1 
ATOM   476  C CG  . LEU A 1 72  ? 1.66200   9.90100   -11.74000 1.000 51.26221  ? 72  LEU A CG  1 
ATOM   477  C CD1 . LEU A 1 72  ? 2.79700   10.86100  -11.38000 1.000 48.80055  ? 72  LEU A CD1 1 
ATOM   478  C CD2 . LEU A 1 72  ? 0.65900   10.53800  -12.70200 1.000 46.88642  ? 72  LEU A CD2 1 
ATOM   479  N N   . ALA A 1 73  ? 2.46800   5.50000   -13.17000 1.000 51.45175  ? 73  ALA A N   1 
ATOM   480  C CA  . ALA A 1 73  ? 2.95400   4.50100   -14.11700 1.000 54.63849  ? 73  ALA A CA  1 
ATOM   481  C C   . ALA A 1 73  ? 1.79800   3.80500   -14.82100 1.000 60.79052  ? 73  ALA A C   1 
ATOM   482  O O   . ALA A 1 73  ? 1.86100   3.54600   -16.02800 1.000 67.54396  ? 73  ALA A O   1 
ATOM   483  C CB  . ALA A 1 73  ? 3.83800   3.48000   -13.40400 1.000 52.88175  ? 73  ALA A CB  1 
ATOM   484  N N   . GLN A 1 74  ? 0.72700   3.51000   -14.08600 1.000 63.00529  ? 74  GLN A N   1 
ATOM   485  C CA  . GLN A 1 74  ? -0.44000  2.82800   -14.62600 1.000 62.69533  ? 74  GLN A CA  1 
ATOM   486  C C   . GLN A 1 74  ? -1.41800  3.78000   -15.28900 1.000 58.79469  ? 74  GLN A C   1 
ATOM   487  O O   . GLN A 1 74  ? -2.55600  3.38500   -15.58200 1.000 59.13218  ? 74  GLN A O   1 
ATOM   488  C CB  . GLN A 1 74  ? -1.14600  2.04000   -13.51800 1.000 59.88325  ? 74  GLN A CB  1 
ATOM   489  C CG  . GLN A 1 74  ? -0.32600  0.89800   -12.93500 1.000 60.96843  ? 74  GLN A CG  1 
ATOM   490  C CD  . GLN A 1 74  ? -0.02500  -0.19300  -13.95700 1.000 68.47309  ? 74  GLN A CD  1 
ATOM   491  O OE1 . GLN A 1 74  ? -0.64500  -0.25900  -15.03000 1.000 66.58920  ? 74  GLN A OE1 1 
ATOM   492  N NE2 . GLN A 1 74  ? 0.93400   -1.05700  -13.62600 1.000 69.46377  ? 74  GLN A NE2 1 
ATOM   493  N N   . TRP A 1 75  ? -0.99700  5.01800   -15.54000 1.000 60.23316  ? 75  TRP A N   1 
ATOM   494  C CA  . TRP A 1 75  ? -1.95200  6.06400   -15.88900 1.000 64.14397  ? 75  TRP A CA  1 
ATOM   495  C C   . TRP A 1 75  ? -2.70500  5.73300   -17.16600 1.000 60.20912  ? 75  TRP A C   1 
ATOM   496  O O   . TRP A 1 75  ? -3.93100  5.89600   -17.23100 1.000 56.86857  ? 75  TRP A O   1 
ATOM   497  C CB  . TRP A 1 75  ? -1.24400  7.41100   -16.02000 1.000 58.67045  ? 75  TRP A CB  1 
ATOM   498  C CG  . TRP A 1 75  ? -2.20000  8.51300   -16.31600 1.000 59.65753  ? 75  TRP A CG  1 
ATOM   499  C CD1 . TRP A 1 75  ? -2.33100  9.19100   -17.49000 1.000 53.44555  ? 75  TRP A CD1 1 
ATOM   500  C CD2 . TRP A 1 75  ? -3.18700  9.05400   -15.42500 1.000 60.39624  ? 75  TRP A CD2 1 
ATOM   501  N NE1 . TRP A 1 75  ? -3.32700  10.13300  -17.38000 1.000 59.98848  ? 75  TRP A NE1 1 
ATOM   502  C CE2 . TRP A 1 75  ? -3.86700  10.07000  -16.12300 1.000 58.35018  ? 75  TRP A CE2 1 
ATOM   503  C CE3 . TRP A 1 75  ? -3.54800  8.78900   -14.09900 1.000 52.44304  ? 75  TRP A CE3 1 
ATOM   504  C CZ2 . TRP A 1 75  ? -4.89400  10.80900  -15.54900 1.000 42.85973  ? 75  TRP A CZ2 1 
ATOM   505  C CZ3 . TRP A 1 75  ? -4.56100  9.52800   -13.53000 1.000 46.17510  ? 75  TRP A CZ3 1 
ATOM   506  C CH2 . TRP A 1 75  ? -5.22200  10.52400  -14.25500 1.000 50.71022  ? 75  TRP A CH2 1 
ATOM   507  N N   . GLU A 1 76  ? -1.98500  5.26100   -18.19400 1.000 62.27499  ? 76  GLU A N   1 
ATOM   508  C CA  . GLU A 1 76  ? -2.60900  5.11800   -19.50900 1.000 66.54964  ? 76  GLU A CA  1 
ATOM   509  C C   . GLU A 1 76  ? -3.63200  3.98700   -19.54600 1.000 62.05397  ? 76  GLU A C   1 
ATOM   510  O O   . GLU A 1 76  ? -4.73500  4.19900   -20.08500 1.000 61.91644  ? 76  GLU A O   1 
ATOM   511  C CB  . GLU A 1 76  ? -1.53300  4.96300   -20.59000 1.000 71.22886  ? 76  GLU A CB  1 
ATOM   512  C CG  . GLU A 1 76  ? -2.01700  5.25900   -22.02700 1.000 78.35860  ? 76  GLU A CG  1 
ATOM   513  C CD  . GLU A 1 76  ? -0.89700  5.14900   -23.06200 1.000 85.01981  ? 76  GLU A CD  1 
ATOM   514  O OE1 . GLU A 1 76  ? 0.28500   5.31800   -22.68000 1.000 83.93976  ? 76  GLU A OE1 1 
ATOM   515  O OE2 . GLU A 1 76  ? -1.20100  4.88700   -24.25300 1.000 81.12595  ? 76  GLU A OE2 1 
ATOM   516  N N   . PRO A 1 77  ? -3.36800  2.79300   -19.00200 1.000 60.68251  ? 77  PRO A N   1 
ATOM   517  C CA  . PRO A 1 77  ? -4.45900  1.81200   -18.91900 1.000 55.80789  ? 77  PRO A CA  1 
ATOM   518  C C   . PRO A 1 77  ? -5.57300  2.27200   -18.00900 1.000 54.75655  ? 77  PRO A C   1 
ATOM   519  O O   . PRO A 1 77  ? -6.74200  1.96400   -18.28000 1.000 55.53816  ? 77  PRO A O   1 
ATOM   520  C CB  . PRO A 1 77  ? -3.76800  0.54800   -18.38600 1.000 59.96901  ? 77  PRO A CB  1 
ATOM   521  C CG  . PRO A 1 77  ? -2.53700  1.02800   -17.74300 1.000 56.23555  ? 77  PRO A CG  1 
ATOM   522  C CD  . PRO A 1 77  ? -2.09600  2.22400   -18.52300 1.000 57.99959  ? 77  PRO A CD  1 
ATOM   523  N N   . LEU A 1 78  ? -5.25100  3.02000   -16.95000 1.000 51.42518  ? 78  LEU A N   1 
ATOM   524  C CA  . LEU A 1 78  ? -6.29800  3.58500   -16.10400 1.000 54.17645  ? 78  LEU A CA  1 
ATOM   525  C C   . LEU A 1 78  ? -7.22000  4.50700   -16.89800 1.000 55.59238  ? 78  LEU A C   1 
ATOM   526  O O   . LEU A 1 78  ? -8.44900  4.43800   -16.75600 1.000 56.94470  ? 78  LEU A O   1 
ATOM   527  C CB  . LEU A 1 78  ? -5.68000  4.32900   -14.91900 1.000 49.76793  ? 78  LEU A CB  1 
ATOM   528  C CG  . LEU A 1 78  ? -6.67900  4.93700   -13.93900 1.000 42.41697  ? 78  LEU A CG  1 
ATOM   529  C CD1 . LEU A 1 78  ? -7.67800  3.88300   -13.44800 1.000 40.17084  ? 78  LEU A CD1 1 
ATOM   530  C CD2 . LEU A 1 78  ? -5.94800  5.59300   -12.77800 1.000 46.85205  ? 78  LEU A CD2 1 
ATOM   531  N N   . VAL A 1 79  ? -6.65300  5.37500   -17.74400 1.000 55.34875  ? 79  VAL A N   1 
ATOM   532  C CA  . VAL A 1 79  ? -7.50000  6.25800   -18.54400 1.000 54.74520  ? 79  VAL A CA  1 
ATOM   533  C C   . VAL A 1 79  ? -8.26300  5.45800   -19.59900 1.000 56.12946  ? 79  VAL A C   1 
ATOM   534  O O   . VAL A 1 79  ? -9.43500  5.74100   -19.89100 1.000 55.86004  ? 79  VAL A O   1 
ATOM   535  C CB  . VAL A 1 79  ? -6.66200  7.38400   -19.17800 1.000 59.40560  ? 79  VAL A CB  1 
ATOM   536  C CG1 . VAL A 1 79  ? -7.57000  8.35200   -19.93100 1.000 62.94036  ? 79  VAL A CG1 1 
ATOM   537  C CG2 . VAL A 1 79  ? -5.84800  8.13000   -18.11400 1.000 56.34575  ? 79  VAL A CG2 1 
ATOM   538  N N   . ALA A 1 80  ? -7.62500  4.43800   -20.17000 1.000 55.72311  ? 80  ALA A N   1 
ATOM   539  C CA  . ALA A 1 80  ? -8.26500  3.59700   -21.17300 1.000 55.35633  ? 80  ALA A CA  1 
ATOM   540  C C   . ALA A 1 80  ? -9.34400  2.70100   -20.56800 1.000 57.08217  ? 80  ALA A C   1 
ATOM   541  O O   . ALA A 1 80  ? -10.53300 2.89100   -20.84100 1.000 59.42234  ? 80  ALA A O   1 
ATOM   542  C CB  . ALA A 1 80  ? -7.21500  2.75100   -21.89200 1.000 56.93406  ? 80  ALA A CB  1 
ATOM   543  N N   . ARG A 1 81  ? -8.95500  1.72100   -19.74800 1.000 54.62008  ? 81  ARG A N   1 
ATOM   544  C CA  . ARG A 1 81  ? -9.93900  0.74900   -19.27300 1.000 56.85411  ? 81  ARG A CA  1 
ATOM   545  C C   . ARG A 1 81  ? -10.83800 1.31000   -18.17500 1.000 55.70897  ? 81  ARG A C   1 
ATOM   546  O O   . ARG A 1 81  ? -11.89300 0.72100   -17.90400 1.000 53.09049  ? 81  ARG A O   1 
ATOM   547  C CB  . ARG A 1 81  ? -9.25100  -0.52500  -18.76100 1.000 52.58709  ? 81  ARG A CB  1 
ATOM   548  C CG  . ARG A 1 81  ? -7.87800  -0.82200  -19.37700 1.000 57.12078  ? 81  ARG A CG  1 
ATOM   549  C CD  . ARG A 1 81  ? -7.47700  -2.27900  -19.16000 1.000 58.71979  ? 81  ARG A CD  1 
ATOM   550  N NE  . ARG A 1 81  ? -7.94500  -2.78500  -17.87100 1.000 63.19019  ? 81  ARG A NE  1 
ATOM   551  C CZ  . ARG A 1 81  ? -7.16800  -3.06600  -16.82900 1.000 61.23526  ? 81  ARG A CZ  1 
ATOM   552  N NH1 . ARG A 1 81  ? -5.85000  -2.92000  -16.88200 1.000 64.53821  ? 81  ARG A NH1 1 
ATOM   553  N NH2 . ARG A 1 81  ? -7.72800  -3.51400  -15.70500 1.000 52.05951  ? 81  ARG A NH2 1 
ATOM   554  N N   . GLY A 1 82  ? -10.44700 2.41900   -17.53400 1.000 52.24815  ? 82  GLY A N   1 
ATOM   555  C CA  . GLY A 1 82  ? -11.22200 2.98300   -16.44100 1.000 46.48929  ? 82  GLY A CA  1 
ATOM   556  C C   . GLY A 1 82  ? -11.12300 2.24600   -15.12000 1.000 49.11366  ? 82  GLY A C   1 
ATOM   557  O O   . GLY A 1 82  ? -11.83900 2.59300   -14.17800 1.000 41.95549  ? 82  GLY A O   1 
ATOM   558  N N   . SER A 1 83  ? -10.27400 1.22600   -15.02400 1.000 45.67098  ? 83  SER A N   1 
ATOM   559  C CA  . SER A 1 83  ? -10.06000 0.50000   -13.78100 1.000 42.19801  ? 83  SER A CA  1 
ATOM   560  C C   . SER A 1 83  ? -8.71500  -0.19200  -13.87900 1.000 41.83626  ? 83  SER A C   1 
ATOM   561  O O   . SER A 1 83  ? -8.30300  -0.60000  -14.96700 1.000 46.59101  ? 83  SER A O   1 
ATOM   562  C CB  . SER A 1 83  ? -11.15900 -0.52700  -13.51900 1.000 41.18850  ? 83  SER A CB  1 
ATOM   563  O OG  . SER A 1 83  ? -10.76700 -1.43400  -12.50200 1.000 37.26960  ? 83  SER A OG  1 
ATOM   564  N N   . VAL A 1 84  ? -8.03300  -0.32900  -12.74300 1.000 39.86280  ? 84  VAL A N   1 
ATOM   565  C CA  . VAL A 1 84  ? -6.67100  -0.84300  -12.80300 1.000 38.00896  ? 84  VAL A CA  1 
ATOM   566  C C   . VAL A 1 84  ? -6.15000  -1.20300  -11.41700 1.000 36.58718  ? 84  VAL A C   1 
ATOM   567  O O   . VAL A 1 84  ? -6.48000  -0.55700  -10.41300 1.000 40.73098  ? 84  VAL A O   1 
ATOM   568  C CB  . VAL A 1 84  ? -5.75300  0.17500   -13.51500 1.000 37.46839  ? 84  VAL A CB  1 
ATOM   569  C CG1 . VAL A 1 84  ? -4.82600  0.89100   -12.53200 1.000 42.10021  ? 84  VAL A CG1 1 
ATOM   570  C CG2 . VAL A 1 84  ? -4.96700  -0.49800  -14.62800 1.000 45.31680  ? 84  VAL A CG2 1 
ATOM   571  N N   . ARG A 1 85  ? -5.34200  -2.25100  -11.35900 1.000 30.88228  ? 85  ARG A N   1 
ATOM   572  C CA  . ARG A 1 85  ? -4.68700  -2.67400  -10.13300 1.000 36.83585  ? 85  ARG A CA  1 
ATOM   573  C C   . ARG A 1 85  ? -3.30300  -2.02500  -10.06800 1.000 40.11560  ? 85  ARG A C   1 
ATOM   574  O O   . ARG A 1 85  ? -2.50900  -2.16300  -11.00800 1.000 40.85706  ? 85  ARG A O   1 
ATOM   575  C CB  . ARG A 1 85  ? -4.59300  -4.19800  -10.12400 1.000 36.53798  ? 85  ARG A CB  1 
ATOM   576  C CG  . ARG A 1 85  ? -4.11400  -4.82300  -8.85200  1.000 42.78434  ? 85  ARG A CG  1 
ATOM   577  C CD  . ARG A 1 85  ? -3.78100  -6.29500  -9.06800  1.000 39.24226  ? 85  ARG A CD  1 
ATOM   578  N NE  . ARG A 1 85  ? -3.23000  -6.88000  -7.84800  1.000 43.49484  ? 85  ARG A NE  1 
ATOM   579  C CZ  . ARG A 1 85  ? -3.97900  -7.41000  -6.89100  1.000 45.38932  ? 85  ARG A CZ  1 
ATOM   580  N NH1 . ARG A 1 85  ? -5.29700  -7.48900  -7.01400  1.000 35.91091  ? 85  ARG A NH1 1 
ATOM   581  N NH2 . ARG A 1 85  ? -3.39600  -7.85600  -5.77800  1.000 41.03337  ? 85  ARG A NH2 1 
ATOM   582  N N   . VAL A 1 86  ? -3.03000  -1.28200  -8.98600  1.000 38.18378  ? 86  VAL A N   1 
ATOM   583  C CA  . VAL A 1 86  ? -1.70700  -0.71200  -8.73200  1.000 40.16890  ? 86  VAL A CA  1 
ATOM   584  C C   . VAL A 1 86  ? -1.22700  -1.20200  -7.37700  1.000 34.21311  ? 86  VAL A C   1 
ATOM   585  O O   . VAL A 1 86  ? -2.02300  -1.39400  -6.45200  1.000 34.67417  ? 86  VAL A O   1 
ATOM   586  C CB  . VAL A 1 86  ? -1.67700  0.83900   -8.77200  1.000 42.34832  ? 86  VAL A CB  1 
ATOM   587  C CG1 . VAL A 1 86  ? -2.28200  1.36000   -10.05400 1.000 42.31755  ? 86  VAL A CG1 1 
ATOM   588  C CG2 . VAL A 1 86  ? -2.36500  1.44600   -7.56100  1.000 35.07183  ? 86  VAL A CG2 1 
ATOM   589  N N   . VAL A 1 87  ? 0.08100   -1.41100  -7.25900  1.000 37.89863  ? 87  VAL A N   1 
ATOM   590  C CA  . VAL A 1 87  ? 0.68800   -1.89600  -6.02100  1.000 38.07578  ? 87  VAL A CA  1 
ATOM   591  C C   . VAL A 1 87  ? 1.37200   -0.72400  -5.32300  1.000 43.77479  ? 87  VAL A C   1 
ATOM   592  O O   . VAL A 1 87  ? 2.39900   -0.21500  -5.78400  1.000 43.69612  ? 87  VAL A O   1 
ATOM   593  C CB  . VAL A 1 87  ? 1.67000   -3.04600  -6.27400  1.000 41.09257  ? 87  VAL A CB  1 
ATOM   594  C CG1 . VAL A 1 87  ? 2.42200   -3.36400  -5.00100  1.000 40.44343  ? 87  VAL A CG1 1 
ATOM   595  C CG2 . VAL A 1 87  ? 0.93200   -4.28500  -6.73100  1.000 38.63737  ? 87  VAL A CG2 1 
ATOM   596  N N   . LEU A 1 88  ? 0.79700   -0.29300  -4.20800  1.000 46.48129  ? 88  LEU A N   1 
ATOM   597  C CA  . LEU A 1 88  ? 1.24100   0.82800   -3.39800  1.000 39.73252  ? 88  LEU A CA  1 
ATOM   598  C C   . LEU A 1 88  ? 1.97200   0.32700   -2.15800  1.000 46.22796  ? 88  LEU A C   1 
ATOM   599  O O   . LEU A 1 88  ? 1.85600   -0.84800  -1.78500  1.000 39.52792  ? 88  LEU A O   1 
ATOM   600  C CB  . LEU A 1 88  ? 0.03700   1.68500   -2.99300  1.000 34.97418  ? 88  LEU A CB  1 
ATOM   601  C CG  . LEU A 1 88  ? -0.63200  2.50900   -4.10700  1.000 45.15196  ? 88  LEU A CG  1 
ATOM   602  C CD1 . LEU A 1 88  ? -1.89000  3.26000   -3.61700  1.000 38.86169  ? 88  LEU A CD1 1 
ATOM   603  C CD2 . LEU A 1 88  ? 0.35800   3.49500   -4.74500  1.000 49.29657  ? 88  LEU A CD2 1 
ATOM   604  N N   . PRO A 1 89  ? 2.77400   1.18800   -1.51400  1.000 49.25979  ? 89  PRO A N   1 
ATOM   605  C CA  . PRO A 1 89  ? 3.42200   0.78400   -0.25300  1.000 44.12453  ? 89  PRO A CA  1 
ATOM   606  C C   . PRO A 1 89  ? 2.44900   0.23800   0.76800   1.000 44.60794  ? 89  PRO A C   1 
ATOM   607  O O   . PRO A 1 89  ? 2.76000   -0.74400  1.45100   1.000 52.14025  ? 89  PRO A O   1 
ATOM   608  C CB  . PRO A 1 89  ? 4.07100   2.08400   0.22400   1.000 43.98421  ? 89  PRO A CB  1 
ATOM   609  C CG  . PRO A 1 89  ? 4.39900   2.81200   -1.05400  1.000 44.35673  ? 89  PRO A CG  1 
ATOM   610  C CD  . PRO A 1 89  ? 3.28100   2.48500   -2.00700  1.000 48.42151  ? 89  PRO A CD  1 
ATOM   611  N N   . ALA A 1 90  ? 1.26000   0.83300   0.86300   1.000 46.88200  ? 90  ALA A N   1 
ATOM   612  C CA  . ALA A 1 90  ? 0.21600   0.39700   1.77900   1.000 46.25646  ? 90  ALA A CA  1 
ATOM   613  C C   . ALA A 1 90  ? -0.50000  -0.86800  1.32000   1.000 43.59961  ? 90  ALA A C   1 
ATOM   614  O O   . ALA A 1 90  ? -1.39500  -1.33100  2.03200   1.000 46.26593  ? 90  ALA A O   1 
ATOM   615  C CB  . ALA A 1 90  ? -0.80900  1.52400   1.98700   1.000 45.74380  ? 90  ALA A CB  1 
ATOM   616  N N   . GLY A 1 91  ? -0.14300  -1.43200  0.16400   1.000 43.66327  ? 91  GLY A N   1 
ATOM   617  C CA  . GLY A 1 91  ? -0.68800  -2.68600  -0.32500  1.000 47.81805  ? 91  GLY A CA  1 
ATOM   618  C C   . GLY A 1 91  ? -1.19700  -2.55300  -1.75300  1.000 44.54966  ? 91  GLY A C   1 
ATOM   619  O O   . GLY A 1 91  ? -1.00000  -1.53200  -2.42200  1.000 40.95012  ? 91  GLY A O   1 
ATOM   620  N N   . ALA A 1 92  ? -1.85800  -3.60700  -2.23400  1.000 43.32993  ? 92  ALA A N   1 
ATOM   621  C CA  . ALA A 1 92  ? -2.44300  -3.59400  -3.57300  1.000 42.77268  ? 92  ALA A CA  1 
ATOM   622  C C   . ALA A 1 92  ? -3.74700  -2.80900  -3.58400  1.000 35.94638  ? 92  ALA A C   1 
ATOM   623  O O   . ALA A 1 92  ? -4.60500  -2.99500  -2.71900  1.000 36.26441  ? 92  ALA A O   1 
ATOM   624  C CB  . ALA A 1 92  ? -2.70300  -5.02100  -4.06500  1.000 37.56537  ? 92  ALA A CB  1 
ATOM   625  N N   . TYR A 1 93  ? -3.91600  -1.95000  -4.58300  1.000 36.97643  ? 93  TYR A N   1 
ATOM   626  C CA  . TYR A 1 93  ? -5.12100  -1.13400  -4.67700  1.000 33.78074  ? 93  TYR A CA  1 
ATOM   627  C C   . TYR A 1 93  ? -5.75500  -1.24000  -6.05900  1.000 32.71186  ? 93  TYR A C   1 
ATOM   628  O O   . TYR A 1 93  ? -5.07500  -1.46400  -7.06500  1.000 34.79203  ? 93  TYR A O   1 
ATOM   629  C CB  . TYR A 1 93  ? -4.81000  0.34200   -4.36000  1.000 37.66061  ? 93  TYR A CB  1 
ATOM   630  C CG  . TYR A 1 93  ? -4.85800  0.67700   -2.89000  1.000 36.65748  ? 93  TYR A CG  1 
ATOM   631  C CD1 . TYR A 1 93  ? -3.75600  0.45600   -2.07100  1.000 43.72058  ? 93  TYR A CD1 1 
ATOM   632  C CD2 . TYR A 1 93  ? -6.00900  1.19900   -2.31500  1.000 36.10455  ? 93  TYR A CD2 1 
ATOM   633  C CE1 . TYR A 1 93  ? -3.79300  0.74900   -0.71200  1.000 46.20586  ? 93  TYR A CE1 1 
ATOM   634  C CE2 . TYR A 1 93  ? -6.06100  1.50400   -0.96000  1.000 41.42690  ? 93  TYR A CE2 1 
ATOM   635  C CZ  . TYR A 1 93  ? -4.94400  1.27900   -0.15900  1.000 50.08951  ? 93  TYR A CZ  1 
ATOM   636  O OH  . TYR A 1 93  ? -4.96900  1.58300   1.19200   1.000 47.60563  ? 93  TYR A OH  1 
ATOM   637  N N   . ARG A 1 94  ? -7.07600  -1.07500  -6.09300  1.000 33.93069  ? 94  ARG A N   1 
ATOM   638  C CA  . ARG A 1 94  ? -7.83700  -0.97300  -7.33200  1.000 30.34475  ? 94  ARG A CA  1 
ATOM   639  C C   . ARG A 1 94  ? -8.14200  0.49800   -7.57400  1.000 36.08786  ? 94  ARG A C   1 
ATOM   640  O O   . ARG A 1 94  ? -8.59600  1.19800   -6.66000  1.000 33.58807  ? 94  ARG A O   1 
ATOM   641  C CB  . ARG A 1 94  ? -9.12000  -1.79700  -7.23300  1.000 33.58520  ? 94  ARG A CB  1 
ATOM   642  C CG  . ARG A 1 94  ? -10.09100 -1.67000  -8.39800  1.000 35.42365  ? 94  ARG A CG  1 
ATOM   643  C CD  . ARG A 1 94  ? -9.49200  -2.14900  -9.69000  1.000 37.97023  ? 94  ARG A CD  1 
ATOM   644  N NE  . ARG A 1 94  ? -9.02900  -3.52900  -9.61700  1.000 41.56197  ? 94  ARG A NE  1 
ATOM   645  C CZ  . ARG A 1 94  ? -8.63200  -4.23700  -10.66500 1.000 40.40365  ? 94  ARG A CZ  1 
ATOM   646  N NH1 . ARG A 1 94  ? -8.70400  -3.75400  -11.89700 1.000 39.50344  ? 94  ARG A NH1 1 
ATOM   647  N NH2 . ARG A 1 94  ? -8.13200  -5.45400  -10.47300 1.000 47.83728  ? 94  ARG A NH2 1 
ATOM   648  N N   . ALA A 1 95  ? -7.85400  0.98000   -8.77900  1.000 34.00576  ? 95  ALA A N   1 
ATOM   649  C CA  . ALA A 1 95  ? -8.04000  2.38800   -9.10900  1.000 33.08219  ? 95  ALA A CA  1 
ATOM   650  C C   . ALA A 1 95  ? -9.16200  2.53500   -10.13500 1.000 35.14269  ? 95  ALA A C   1 
ATOM   651  O O   . ALA A 1 95  ? -9.17100  1.82600   -11.14800 1.000 35.87889  ? 95  ALA A O   1 
ATOM   652  C CB  . ALA A 1 95  ? -6.73500  2.99000   -9.63200  1.000 34.78649  ? 95  ALA A CB  1 
ATOM   653  N N   . LEU A 1 96  ? -10.09900 3.45400   -9.87700  1.000 32.76743  ? 96  LEU A N   1 
ATOM   654  C CA  . LEU A 1 96  ? -11.27200 3.65100   -10.73400 1.000 33.89688  ? 96  LEU A CA  1 
ATOM   655  C C   . LEU A 1 96  ? -11.42300 5.11400   -11.14100 1.000 38.99365  ? 96  LEU A C   1 
ATOM   656  O O   . LEU A 1 96  ? -11.32100 6.01400   -10.30000 1.000 40.94308  ? 96  LEU A O   1 
ATOM   657  C CB  . LEU A 1 96  ? -12.54400 3.18800   -10.02400 1.000 30.42729  ? 96  LEU A CB  1 
ATOM   658  C CG  . LEU A 1 96  ? -12.43800 1.84200   -9.30800  1.000 31.93778  ? 96  LEU A CG  1 
ATOM   659  C CD1 . LEU A 1 96  ? -13.65200 1.59200   -8.42600  1.000 34.64462  ? 96  LEU A CD1 1 
ATOM   660  C CD2 . LEU A 1 96  ? -12.25000 0.70600   -10.31200 1.000 36.51251  ? 96  LEU A CD2 1 
ATOM   661  N N   . LEU A 1 97  ? -11.67500 5.35200   -12.42600 1.000 41.87862  ? 97  LEU A N   1 
ATOM   662  C CA  . LEU A 1 97  ? -11.99000 6.67800   -12.94600 1.000 39.28178  ? 97  LEU A CA  1 
ATOM   663  C C   . LEU A 1 97  ? -13.45300 6.74500   -13.37200 1.000 43.70478  ? 97  LEU A C   1 
ATOM   664  O O   . LEU A 1 97  ? -13.96500 5.82500   -14.02200 1.000 42.79448  ? 97  LEU A O   1 
ATOM   665  C CB  . LEU A 1 97  ? -11.12900 7.03700   -14.16300 1.000 41.96297  ? 97  LEU A CB  1 
ATOM   666  C CG  . LEU A 1 97  ? -9.65900  7.43600   -14.08000 1.000 42.39284  ? 97  LEU A CG  1 
ATOM   667  C CD1 . LEU A 1 97  ? -9.19700  7.77700   -15.47100 1.000 38.83757  ? 97  LEU A CD1 1 
ATOM   668  C CD2 . LEU A 1 97  ? -9.47400  8.61900   -13.16400 1.000 36.05450  ? 97  LEU A CD2 1 
ATOM   669  N N   . HIS A 1 98  ? -14.11800 7.84200   -13.01900 1.000 38.24816  ? 98  HIS A N   1 
ATOM   670  C CA  . HIS A 1 98  ? -15.37200 8.20900   -13.64400 1.000 28.82485  ? 98  HIS A CA  1 
ATOM   671  C C   . HIS A 1 98  ? -15.39800 9.72600   -13.74200 1.000 35.98580  ? 98  HIS A C   1 
ATOM   672  O O   . HIS A 1 98  ? -14.48900 10.41100  -13.25800 1.000 34.86710  ? 98  HIS A O   1 
ATOM   673  C CB  . HIS A 1 98  ? -16.59300 7.62000   -12.89600 1.000 33.89391  ? 98  HIS A CB  1 
ATOM   674  C CG  . HIS A 1 98  ? -16.87400 8.21600   -11.54200 1.000 33.12269  ? 98  HIS A CG  1 
ATOM   675  N ND1 . HIS A 1 98  ? -16.29800 7.74300   -10.38100 1.000 36.16889  ? 98  HIS A ND1 1 
ATOM   676  C CD2 . HIS A 1 98  ? -17.72800 9.19600   -11.15700 1.000 37.24886  ? 98  HIS A CD2 1 
ATOM   677  C CE1 . HIS A 1 98  ? -16.75800 8.42700   -9.34600  1.000 34.61032  ? 98  HIS A CE1 1 
ATOM   678  N NE2 . HIS A 1 98  ? -17.61900 9.32300   -9.79100  1.000 33.94328  ? 98  HIS A NE2 1 
ATOM   679  N N   . GLU A 1 99  ? -16.42200 10.25700  -14.41400 1.000 39.30544  ? 99  GLU A N   1 
ATOM   680  C CA  . GLU A 1 99  ? -16.57300 11.69200  -14.61500 1.000 35.84610  ? 99  GLU A CA  1 
ATOM   681  C C   . GLU A 1 99  ? -17.81400 12.18100  -13.88700 1.000 32.47712  ? 99  GLU A C   1 
ATOM   682  O O   . GLU A 1 99  ? -18.83200 11.48700  -13.85400 1.000 33.95815  ? 99  GLU A O   1 
ATOM   683  C CB  . GLU A 1 99  ? -16.65600 12.02500  -16.10200 1.000 39.06849  ? 99  GLU A CB  1 
ATOM   684  C CG  . GLU A 1 99  ? -15.31600 11.85300  -16.79300 1.000 48.46126  ? 99  GLU A CG  1 
ATOM   685  C CD  . GLU A 1 99  ? -15.43200 11.70800  -18.29100 1.000 59.42053  ? 99  GLU A CD  1 
ATOM   686  O OE1 . GLU A 1 99  ? -16.55700 11.86800  -18.81100 1.000 60.03707  ? 99  GLU A OE1 1 
ATOM   687  O OE2 . GLU A 1 99  ? -14.39500 11.42300  -18.93900 1.000 69.68790  ? 99  GLU A OE2 1 
ATOM   688  N N   . SER A 1 100 ? -17.71200 13.36300  -13.27900 1.000 32.43202  ? 100 SER A N   1 
ATOM   689  C CA  . SER A 1 100 ? -18.80700 13.93900  -12.50300 1.000 35.91068  ? 100 SER A CA  1 
ATOM   690  C C   . SER A 1 100 ? -18.55400 15.43400  -12.36400 1.000 35.36046  ? 100 SER A C   1 
ATOM   691  O O   . SER A 1 100 ? -17.45200 15.83900  -11.97100 1.000 36.76144  ? 100 SER A O   1 
ATOM   692  C CB  . SER A 1 100 ? -18.91600 13.26700  -11.12300 1.000 30.84778  ? 100 SER A CB  1 
ATOM   693  O OG  . SER A 1 100 ? -20.05300 13.72200  -10.40500 1.000 35.55500  ? 100 SER A OG  1 
ATOM   694  N N   . ASP A 1 101 ? -19.55200 16.24600  -12.72000 1.000 30.39423  ? 101 ASP A N   1 
ATOM   695  C CA  . ASP A 1 101 ? -19.45600 17.70500  -12.60500 1.000 33.91973  ? 101 ASP A CA  1 
ATOM   696  C C   . ASP A 1 101 ? -18.25500 18.27400  -13.36100 1.000 36.07687  ? 101 ASP A C   1 
ATOM   697  O O   . ASP A 1 101 ? -17.52500 19.13800  -12.86200 1.000 39.78080  ? 101 ASP A O   1 
ATOM   698  C CB  . ASP A 1 101 ? -19.39100 18.12300  -11.14400 1.000 29.71237  ? 101 ASP A CB  1 
ATOM   699  C CG  . ASP A 1 101 ? -20.63600 17.78000  -10.38900 1.000 35.14949  ? 101 ASP A CG  1 
ATOM   700  O OD1 . ASP A 1 101 ? -21.73700 17.77700  -11.00000 1.000 34.14914  ? 101 ASP A OD1 1 
ATOM   701  O OD2 . ASP A 1 101 ? -20.50400 17.52300  -9.17600  1.000 33.19083  ? 101 ASP A OD2 1 
ATOM   702  N N   . GLY A 1 102 ? -18.04700 17.78700  -14.57900 1.000 34.42731  ? 102 GLY A N   1 
ATOM   703  C CA  . GLY A 1 102 ? -16.91600 18.26300  -15.35200 1.000 35.17302  ? 102 GLY A CA  1 
ATOM   704  C C   . GLY A 1 102 ? -15.56000 17.98100  -14.74000 1.000 38.86281  ? 102 GLY A C   1 
ATOM   705  O O   . GLY A 1 102 ? -14.57200 18.60800  -15.13200 1.000 43.20960  ? 102 GLY A O   1 
ATOM   706  N N   . LEU A 1 103 ? -15.47400 17.05700  -13.78700 1.000 37.14601  ? 103 LEU A N   1 
ATOM   707  C CA  . LEU A 1 103 ? -14.19800 16.64200  -13.22000 1.000 38.52487  ? 103 LEU A CA  1 
ATOM   708  C C   . LEU A 1 103 ? -13.95800 15.17100  -13.51800 1.000 38.97162  ? 103 LEU A C   1 
ATOM   709  O O   . LEU A 1 103 ? -14.89700 14.40700  -13.77500 1.000 37.66410  ? 103 LEU A O   1 
ATOM   710  C CB  . LEU A 1 103 ? -14.14800 16.84500  -11.70700 1.000 36.67134  ? 103 LEU A CB  1 
ATOM   711  C CG  . LEU A 1 103 ? -14.60100 18.18600  -11.17400 1.000 37.00024  ? 103 LEU A CG  1 
ATOM   712  C CD1 . LEU A 1 103 ? -14.81600 18.05900  -9.68800  1.000 30.89772  ? 103 LEU A CD1 1 
ATOM   713  C CD2 . LEU A 1 103 ? -13.51000 19.16300  -11.46400 1.000 45.26231  ? 103 LEU A CD2 1 
ATOM   714  N N   . THR A 1 104 ? -12.67900 14.78100  -13.45900 1.000 36.39119  ? 104 THR A N   1 
ATOM   715  C CA  . THR A 1 104 ? -12.25600 13.38800  -13.56500 1.000 30.88815  ? 104 THR A CA  1 
ATOM   716  C C   . THR A 1 104 ? -12.03600 12.88700  -12.14000 1.000 34.21472  ? 104 THR A C   1 
ATOM   717  O O   . THR A 1 104 ? -11.13400 13.36400  -11.44000 1.000 32.66290  ? 104 THR A O   1 
ATOM   718  C CB  . THR A 1 104 ? -10.98600 13.25500  -14.41000 1.000 36.98896  ? 104 THR A CB  1 
ATOM   719  O OG1 . THR A 1 104 ? -11.25800 13.60300  -15.77500 1.000 37.87862  ? 104 THR A OG1 1 
ATOM   720  C CG2 . THR A 1 104 ? -10.47000 11.85100  -14.38200 1.000 31.86690  ? 104 THR A CG2 1 
ATOM   721  N N   . VAL A 1 105 ? -12.88500 11.96400  -11.69200 1.000 27.52508  ? 105 VAL A N   1 
ATOM   722  C CA  . VAL A 1 105 ? -12.83500 11.45300  -10.32800 1.000 31.45666  ? 105 VAL A CA  1 
ATOM   723  C C   . VAL A 1 105 ? -11.99500 10.18400  -10.33000 1.000 34.15928  ? 105 VAL A C   1 
ATOM   724  O O   . VAL A 1 105 ? -12.22200 9.28100   -11.14900 1.000 39.40082  ? 105 VAL A O   1 
ATOM   725  C CB  . VAL A 1 105 ? -14.24800 11.17600  -9.77700  1.000 34.69343  ? 105 VAL A CB  1 
ATOM   726  C CG1 . VAL A 1 105 ? -14.18000 10.67300  -8.35000  1.000 28.95266  ? 105 VAL A CG1 1 
ATOM   727  C CG2 . VAL A 1 105 ? -15.12100 12.42500  -9.87600  1.000 30.63072  ? 105 VAL A CG2 1 
ATOM   728  N N   . LEU A 1 106 ? -11.01500 10.12100  -9.43100  1.000 32.49807  ? 106 LEU A N   1 
ATOM   729  C CA  . LEU A 1 106 ? -10.20400 8.93100   -9.22000  1.000 26.03029  ? 106 LEU A CA  1 
ATOM   730  C C   . LEU A 1 106 ? -10.46100 8.42900   -7.81200  1.000 29.96133  ? 106 LEU A C   1 
ATOM   731  O O   . LEU A 1 106 ? -10.22700 9.14800   -6.83900  1.000 32.39157  ? 106 LEU A O   1 
ATOM   732  C CB  . LEU A 1 106 ? -8.72400  9.23400   -9.41400  1.000 36.09691  ? 106 LEU A CB  1 
ATOM   733  C CG  . LEU A 1 106 ? -7.72100  8.16900   -8.95500  1.000 35.19027  ? 106 LEU A CG  1 
ATOM   734  C CD1 . LEU A 1 106 ? -7.89600  6.86600   -9.72200  1.000 37.35847  ? 106 LEU A CD1 1 
ATOM   735  C CD2 . LEU A 1 106 ? -6.28600  8.71400   -9.08800  1.000 34.41079  ? 106 LEU A CD2 1 
ATOM   736  N N   . GLU A 1 107 ? -10.95000 7.20800   -7.70200  1.000 32.76105  ? 107 GLU A N   1 
ATOM   737  C CA  . GLU A 1 107 ? -11.16300 6.57500   -6.41600  1.000 31.55799  ? 107 GLU A CA  1 
ATOM   738  C C   . GLU A 1 107 ? -10.18100 5.42000   -6.23700  1.000 30.09321  ? 107 GLU A C   1 
ATOM   739  O O   . GLU A 1 107 ? -9.94100  4.64600   -7.17200  1.000 30.58046  ? 107 GLU A O   1 
ATOM   740  C CB  . GLU A 1 107 ? -12.60500 6.09000   -6.31400  1.000 28.73982  ? 107 GLU A CB  1 
ATOM   741  C CG  . GLU A 1 107 ? -13.59900 7.19300   -5.99400  1.000 29.38572  ? 107 GLU A CG  1 
ATOM   742  C CD  . GLU A 1 107 ? -15.03100 6.66900   -6.00500  1.000 33.22002  ? 107 GLU A CD  1 
ATOM   743  O OE1 . GLU A 1 107 ? -15.39300 5.94200   -6.96800  1.000 30.70454  ? 107 GLU A OE1 1 
ATOM   744  O OE2 . GLU A 1 107 ? -15.77700 6.95400   -5.03600  1.000 32.78340  ? 107 GLU A OE2 1 
ATOM   745  N N   . LEU A 1 108 ? -9.60300  5.32100   -5.03900  1.000 33.95316  ? 108 LEU A N   1 
ATOM   746  C CA  . LEU A 1 108 ? -8.66800  4.25800   -4.66200  1.000 36.14629  ? 108 LEU A CA  1 
ATOM   747  C C   . LEU A 1 108 ? -9.27500  3.39100   -3.56800  1.000 31.90503  ? 108 LEU A C   1 
ATOM   748  O O   . LEU A 1 108 ? -9.86300  3.90600   -2.61000  1.000 30.37220  ? 108 LEU A O   1 
ATOM   749  C CB  . LEU A 1 108 ? -7.33600  4.82300   -4.15700  1.000 32.13624  ? 108 LEU A CB  1 
ATOM   750  C CG  . LEU A 1 108 ? -6.34100  5.20900   -5.25000  1.000 36.11081  ? 108 LEU A CG  1 
ATOM   751  C CD1 . LEU A 1 108 ? -5.50500  6.39000   -4.80000  1.000 33.86012  ? 108 LEU A CD1 1 
ATOM   752  C CD2 . LEU A 1 108 ? -5.45700  4.02700   -5.56900  1.000 31.35742  ? 108 LEU A CD2 1 
ATOM   753  N N   . GLU A 1 109 ? -9.09300  2.07300   -3.69700  1.000 35.03149  ? 109 GLU A N   1 
ATOM   754  C CA  . GLU A 1 109 ? -9.78400  1.07900   -2.88200  1.000 31.41453  ? 109 GLU A CA  1 
ATOM   755  C C   . GLU A 1 109 ? -8.93600  -0.17800  -2.80000  1.000 31.10326  ? 109 GLU A C   1 
ATOM   756  O O   . GLU A 1 109 ? -8.34000  -0.57900  -3.81300  1.000 32.42648  ? 109 GLU A O   1 
ATOM   757  C CB  . GLU A 1 109 ? -11.15600 0.74800   -3.48900  1.000 29.68540  ? 109 GLU A CB  1 
ATOM   758  C CG  . GLU A 1 109 ? -11.90800 -0.34600  -2.79800  1.000 31.84864  ? 109 GLU A CG  1 
ATOM   759  C CD  . GLU A 1 109 ? -13.34500 -0.42600  -3.23900  1.000 30.16794  ? 109 GLU A CD  1 
ATOM   760  O OE1 . GLU A 1 109 ? -13.68600 0.16500   -4.27800  1.000 33.48277  ? 109 GLU A OE1 1 
ATOM   761  O OE2 . GLU A 1 109 ? -14.13000 -1.09100  -2.53900  1.000 36.71763  ? 109 GLU A OE2 1 
ATOM   762  N N   . PRO A 1 110 ? -8.85500  -0.81600  -1.63600  1.000 30.74372  ? 110 PRO A N   1 
ATOM   763  C CA  . PRO A 1 110 ? -8.06000  -2.04400  -1.53100  1.000 29.50544  ? 110 PRO A CA  1 
ATOM   764  C C   . PRO A 1 110 ? -8.54300  -3.08900  -2.52400  1.000 30.43897  ? 110 PRO A C   1 
ATOM   765  O O   . PRO A 1 110 ? -9.74700  -3.24100  -2.75400  1.000 32.99780  ? 110 PRO A O   1 
ATOM   766  C CB  . PRO A 1 110 ? -8.28600  -2.48600  -0.08600  1.000 19.41496  ? 110 PRO A CB  1 
ATOM   767  C CG  . PRO A 1 110 ? -8.64500  -1.24300  0.61900   1.000 30.02571  ? 110 PRO A CG  1 
ATOM   768  C CD  . PRO A 1 110 ? -9.46100  -0.44900  -0.34600  1.000 30.07598  ? 110 PRO A CD  1 
ATOM   769  N N   . ALA A 1 111 ? -7.58600  -3.81500  -3.10800  1.000 27.37473  ? 111 ALA A N   1 
ATOM   770  C CA  . ALA A 1 111 ? -7.84900  -4.69000  -4.23900  1.000 29.77995  ? 111 ALA A CA  1 
ATOM   771  C C   . ALA A 1 111 ? -8.16900  -6.10400  -3.76400  1.000 28.81909  ? 111 ALA A C   1 
ATOM   772  O O   . ALA A 1 111 ? -8.15000  -6.41300  -2.57100  1.000 36.51846  ? 111 ALA A O   1 
ATOM   773  C CB  . ALA A 1 111 ? -6.66000  -4.68200  -5.20100  1.000 31.71234  ? 111 ALA A CB  1 
ATOM   774  N N   . GLU A 1 112 ? -8.48100  -6.97900  -4.70900  1.000 30.96172  ? 112 GLU A N   1 
ATOM   775  C CA  . GLU A 1 112 ? -8.76600  -8.36600  -4.37800  1.000 35.14091  ? 112 GLU A CA  1 
ATOM   776  C C   . GLU A 1 112 ? -7.46200  -9.07500  -4.07000  1.000 34.55318  ? 112 GLU A C   1 
ATOM   777  O O   . GLU A 1 112 ? -6.45500  -8.86200  -4.75000  1.000 33.86600  ? 112 GLU A O   1 
ATOM   778  C CB  . GLU A 1 112 ? -9.49100  -9.05000  -5.53700  1.000 35.17848  ? 112 GLU A CB  1 
ATOM   779  C CG  . GLU A 1 112 ? -9.74400  -10.52200 -5.34900  1.000 30.19862  ? 112 GLU A CG  1 
ATOM   780  C CD  . GLU A 1 112 ? -10.49600 -10.81400 -4.09600  1.000 35.53669  ? 112 GLU A CD  1 
ATOM   781  O OE1 . GLU A 1 112 ? -11.71700 -10.50500 -4.03600  1.000 32.64929  ? 112 GLU A OE1 1 
ATOM   782  O OE2 . GLU A 1 112 ? -9.85700  -11.35200 -3.16400  1.000 35.44852  ? 112 GLU A OE2 1 
ATOM   783  N N   . LEU A 1 113 ? -7.46800  -9.89500  -3.02000  1.000 40.03244  ? 113 LEU A N   1 
ATOM   784  C CA  . LEU A 1 113 ? -6.24900  -10.58500 -2.60700  1.000 42.55827  ? 113 LEU A CA  1 
ATOM   785  C C   . LEU A 1 113 ? -6.21900  -12.05100 -3.01300  1.000 44.44247  ? 113 LEU A C   1 
ATOM   786  O O   . LEU A 1 113 ? -5.14700  -12.55400 -3.35600  1.000 49.56811  ? 113 LEU A O   1 
ATOM   787  C CB  . LEU A 1 113 ? -6.04200  -10.45900 -1.09800  1.000 39.67838  ? 113 LEU A CB  1 
ATOM   788  C CG  . LEU A 1 113 ? -5.51200  -9.06700  -0.69700  1.000 44.20634  ? 113 LEU A CG  1 
ATOM   789  C CD1 . LEU A 1 113 ? -4.96000  -9.03100  0.72100   1.000 45.79397  ? 113 LEU A CD1 1 
ATOM   790  C CD2 . LEU A 1 113 ? -4.47900  -8.54100  -1.69000  1.000 43.04085  ? 113 LEU A CD2 1 
ATOM   791  N N   . GLN A 1 114 ? -7.35800  -12.73800 -3.01100  1.000 40.04277  ? 114 GLN A N   1 
ATOM   792  C CA  . GLN A 1 114 ? -7.42200  -14.12300 -3.46000  1.000 39.82828  ? 114 GLN A CA  1 
ATOM   793  C C   . GLN A 1 114 ? -7.16200  -14.20800 -4.96300  1.000 49.46218  ? 114 GLN A C   1 
ATOM   794  O O   . GLN A 1 114 ? -7.99900  -13.74200 -5.75700  1.000 43.74766  ? 114 GLN A O   1 
ATOM   795  C CB  . GLN A 1 114 ? -8.78600  -14.73100 -3.12400  1.000 43.83321  ? 114 GLN A CB  1 
ATOM   796  C CG  . GLN A 1 114 ? -9.17000  -14.59700 -1.66800  1.000 46.96963  ? 114 GLN A CG  1 
ATOM   797  C CD  . GLN A 1 114 ? -8.15200  -15.22600 -0.73400  1.000 59.10362  ? 114 GLN A CD  1 
ATOM   798  O OE1 . GLN A 1 114 ? -7.54700  -16.25700 -1.05200  1.000 67.01258  ? 114 GLN A OE1 1 
ATOM   799  N NE2 . GLN A 1 114 ? -7.95100  -14.60300 0.42800   1.000 62.85768  ? 114 GLN A NE2 1 
ATOM   800  N N   . PRO A 1 115 ? -6.03800  -14.78900 -5.40300  1.000 49.23227  ? 115 PRO A N   1 
ATOM   801  C CA  . PRO A 1 115 ? -5.76000  -14.83400 -6.84400  1.000 46.48955  ? 115 PRO A CA  1 
ATOM   802  C C   . PRO A 1 115 ? -6.66400  -15.77900 -7.59700  1.000 46.27534  ? 115 PRO A C   1 
ATOM   803  O O   . PRO A 1 115 ? -6.75200  -15.66500 -8.82800  1.000 48.48264  ? 115 PRO A O   1 
ATOM   804  C CB  . PRO A 1 115 ? -4.30100  -15.29400 -6.90200  1.000 43.35221  ? 115 PRO A CB  1 
ATOM   805  C CG  . PRO A 1 115 ? -4.14100  -16.08500 -5.67000  1.000 43.15542  ? 115 PRO A CG  1 
ATOM   806  C CD  . PRO A 1 115 ? -4.95000  -15.40200 -4.62300  1.000 44.53155  ? 115 PRO A CD  1 
ATOM   807  N N   . GLY A 1 116 ? -7.34000  -16.70000 -6.91000  1.000 44.08804  ? 116 GLY A N   1 
ATOM   808  C CA  . GLY A 1 116 ? -8.21700  -17.64300 -7.58600  1.000 41.76161  ? 116 GLY A CA  1 
ATOM   809  C C   . GLY A 1 116 ? -9.66000  -17.19100 -7.53000  1.000 43.84924  ? 116 GLY A C   1 
ATOM   810  O O   . GLY A 1 116 ? -10.59700 -17.98300 -7.70400  1.000 37.41648  ? 116 GLY A O   1 
ATOM   811  N N   . MET A 1 117 ? -9.83200  -15.89400 -7.27200  1.000 41.79687  ? 117 MET A N   1 
ATOM   812  C CA  . MET A 1 117 ? -11.16300 -15.33900 -7.08600  1.000 35.19793  ? 117 MET A CA  1 
ATOM   813  C C   . MET A 1 117 ? -12.04900 -15.61600 -8.29900  1.000 36.15580  ? 117 MET A C   1 
ATOM   814  O O   . MET A 1 117 ? -13.17000 -16.11100 -8.15500  1.000 33.90543  ? 117 MET A O   1 
ATOM   815  C CB  . MET A 1 117 ? -11.04600 -13.84100 -6.79800  1.000 28.96392  ? 117 MET A CB  1 
ATOM   816  C CG  . MET A 1 117 ? -12.33800 -13.17200 -6.32100  1.000 36.19921  ? 117 MET A CG  1 
ATOM   817  S SD  . MET A 1 117 ? -13.54200 -12.84700 -7.65800  1.000 38.31917  ? 117 MET A SD  1 
ATOM   818  C CE  . MET A 1 117 ? -12.70500 -11.52900 -8.54400  1.000 31.43675  ? 117 MET A CE  1 
ATOM   819  N N   . GLU A 1 118 ? -11.56300 -15.31200 -9.50800  1.000 38.22813  ? 118 GLU A N   1 
ATOM   820  C CA  . GLU A 1 118 ? -12.43800 -15.39500 -10.68200 1.000 39.08298  ? 118 GLU A CA  1 
ATOM   821  C C   . GLU A 1 118 ? -12.75300 -16.83800 -11.05300 1.000 42.79826  ? 118 GLU A C   1 
ATOM   822  O O   . GLU A 1 118 ? -13.82500 -17.12000 -11.61000 1.000 43.87884  ? 118 GLU A O   1 
ATOM   823  C CB  . GLU A 1 118 ? -11.81100 -14.67500 -11.87500 1.000 41.33880  ? 118 GLU A CB  1 
ATOM   824  C CG  . GLU A 1 118 ? -11.71200 -13.17300 -11.72500 1.000 41.38934  ? 118 GLU A CG  1 
ATOM   825  C CD  . GLU A 1 118 ? -10.48000 -12.72300 -10.95500 1.000 40.14628  ? 118 GLU A CD  1 
ATOM   826  O OE1 . GLU A 1 118 ? -9.72500  -13.58000 -10.43400 1.000 40.19672  ? 118 GLU A OE1 1 
ATOM   827  O OE2 . GLU A 1 118 ? -10.26900 -11.49600 -10.86800 1.000 46.61309  ? 118 GLU A OE2 1 
ATOM   828  N N   . GLU A 1 119 ? -11.84100 -17.76600 -10.75700 1.000 46.06125  ? 119 GLU A N   1 
ATOM   829  C CA  . GLU A 1 119 ? -12.15500 -19.17800 -10.94100 1.000 41.46147  ? 119 GLU A CA  1 
ATOM   830  C C   . GLU A 1 119 ? -13.30400 -19.59400 -10.04500 1.000 40.30426  ? 119 GLU A C   1 
ATOM   831  O O   . GLU A 1 119 ? -14.11900 -20.43900 -10.42400 1.000 45.48190  ? 119 GLU A O   1 
ATOM   832  C CB  . GLU A 1 119 ? -10.92500 -20.02100 -10.65000 1.000 36.81060  ? 119 GLU A CB  1 
ATOM   833  C CG  . GLU A 1 119 ? -11.10500 -21.48100 -10.93700 1.000 45.04006  ? 119 GLU A CG  1 
ATOM   834  C CD  . GLU A 1 119 ? -9.80300  -22.23600 -10.76300 1.000 56.42210  ? 119 GLU A CD  1 
ATOM   835  O OE1 . GLU A 1 119 ? -8.85200  -21.62200 -10.21500 1.000 55.54913  ? 119 GLU A OE1 1 
ATOM   836  O OE2 . GLU A 1 119 ? -9.72900  -23.42200 -11.18400 1.000 58.21372  ? 119 GLU A OE2 1 
ATOM   837  N N   . THR A 1 120 ? -13.38500 -18.99800 -8.85600  1.000 36.68715  ? 120 THR A N   1 
ATOM   838  C CA  . THR A 1 120 ? -14.47300 -19.29200 -7.93000  1.000 40.31055  ? 120 THR A CA  1 
ATOM   839  C C   . THR A 1 120 ? -15.79000 -18.69900 -8.41800  1.000 43.75642  ? 120 THR A C   1 
ATOM   840  O O   . THR A 1 120 ? -16.85000 -19.32600 -8.28000  1.000 48.48823  ? 120 THR A O   1 
ATOM   841  C CB  . THR A 1 120 ? -14.12300 -18.75900 -6.53600  1.000 36.67559  ? 120 THR A CB  1 
ATOM   842  O OG1 . THR A 1 120 ? -12.94300 -19.42000 -6.04800  1.000 39.17620  ? 120 THR A OG1 1 
ATOM   843  C CG2 . THR A 1 120 ? -15.26700 -18.97200 -5.57100  1.000 29.60635  ? 120 THR A CG2 1 
ATOM   844  N N   . ALA A 1 121 ? -15.74900 -17.48900 -8.98700  1.000 40.06630  ? 121 ALA A N   1 
ATOM   845  C CA  . ALA A 1 121 ? -16.96100 -16.92000 -9.56200  1.000 42.14491  ? 121 ALA A CA  1 
ATOM   846  C C   . ALA A 1 121 ? -17.40800 -17.70700 -10.79400 1.000 42.81968  ? 121 ALA A C   1 
ATOM   847  O O   . ALA A 1 121 ? -18.60700 -17.90600 -11.01800 1.000 39.79803  ? 121 ALA A O   1 
ATOM   848  C CB  . ALA A 1 121 ? -16.73000 -15.44700 -9.90000  1.000 37.34427  ? 121 ALA A CB  1 
ATOM   849  N N   . LEU A 1 122 ? -16.46100 -18.17900 -11.60100 1.000 41.03353  ? 122 LEU A N   1 
ATOM   850  C CA  . LEU A 1 122 ? -16.84600 -18.94400 -12.77900 1.000 43.11379  ? 122 LEU A CA  1 
ATOM   851  C C   . LEU A 1 122 ? -17.56500 -20.23800 -12.39900 1.000 48.38461  ? 122 LEU A C   1 
ATOM   852  O O   . LEU A 1 122 ? -18.47400 -20.67700 -13.11500 1.000 49.19121  ? 122 LEU A O   1 
ATOM   853  C CB  . LEU A 1 122 ? -15.61200 -19.23700 -13.62600 1.000 46.86755  ? 122 LEU A CB  1 
ATOM   854  C CG  . LEU A 1 122 ? -15.87900 -19.60700 -15.07400 1.000 43.18804  ? 122 LEU A CG  1 
ATOM   855  C CD1 . LEU A 1 122 ? -16.49100 -18.42000 -15.78100 1.000 46.27462  ? 122 LEU A CD1 1 
ATOM   856  C CD2 . LEU A 1 122 ? -14.56500 -20.01800 -15.71800 1.000 45.43544  ? 122 LEU A CD2 1 
ATOM   857  N N   . GLU A 1 123 ? -17.19300 -20.86100 -11.27900 1.000 45.27902  ? 123 GLU A N   1 
ATOM   858  C CA  . GLU A 1 123 ? -17.87800 -22.09000 -10.89100 1.000 46.08767  ? 123 GLU A CA  1 
ATOM   859  C C   . GLU A 1 123 ? -19.31300 -21.81700 -10.46100 1.000 48.06422  ? 123 GLU A C   1 
ATOM   860  O O   . GLU A 1 123 ? -20.22200 -22.59100 -10.78400 1.000 45.79393  ? 123 GLU A O   1 
ATOM   861  C CB  . GLU A 1 123 ? -17.12000 -22.79500 -9.76800  1.000 46.98379  ? 123 GLU A CB  1 
ATOM   862  C CG  . GLU A 1 123 ? -15.91800 -23.59400 -10.24600 1.000 59.31807  ? 123 GLU A CG  1 
ATOM   863  C CD  . GLU A 1 123 ? -16.31100 -24.81000 -11.08200 1.000 64.97437  ? 123 GLU A CD  1 
ATOM   864  O OE1 . GLU A 1 123 ? -17.38500 -25.40100 -10.81300 1.000 63.50110  ? 123 GLU A OE1 1 
ATOM   865  O OE2 . GLU A 1 123 ? -15.54800 -25.16900 -12.01100 1.000 67.55899  ? 123 GLU A OE2 1 
ATOM   866  N N   . VAL A 1 124 ? -19.53700 -20.73900 -9.70600  1.000 49.86035  ? 124 VAL A N   1 
ATOM   867  C CA  . VAL A 1 124 ? -20.88900 -20.47500 -9.22900  1.000 43.93627  ? 124 VAL A CA  1 
ATOM   868  C C   . VAL A 1 124 ? -21.76000 -19.95800 -10.36400 1.000 48.35504  ? 124 VAL A C   1 
ATOM   869  O O   . VAL A 1 124 ? -22.98500 -20.14100 -10.34200 1.000 54.23793  ? 124 VAL A O   1 
ATOM   870  C CB  . VAL A 1 124 ? -20.88200 -19.49900 -8.03300  1.000 50.93983  ? 124 VAL A CB  1 
ATOM   871  C CG1 . VAL A 1 124 ? -20.23700 -20.13500 -6.82900  1.000 43.10259  ? 124 VAL A CG1 1 
ATOM   872  C CG2 . VAL A 1 124 ? -20.18200 -18.18900 -8.38700  1.000 46.59020  ? 124 VAL A CG2 1 
ATOM   873  N N   . VAL A 1 125 ? -21.15800 -19.30800 -11.36600 1.000 41.84815  ? 125 VAL A N   1 
ATOM   874  C CA  . VAL A 1 125 ? -21.89100 -18.96900 -12.58600 1.000 42.52486  ? 125 VAL A CA  1 
ATOM   875  C C   . VAL A 1 125 ? -22.41900 -20.22900 -13.26600 1.000 45.27476  ? 125 VAL A C   1 
ATOM   876  O O   . VAL A 1 125 ? -23.52100 -20.22800 -13.83200 1.000 46.73450  ? 125 VAL A O   1 
ATOM   877  C CB  . VAL A 1 125 ? -20.99700 -18.14600 -13.53100 1.000 40.14215  ? 125 VAL A CB  1 
ATOM   878  C CG1 . VAL A 1 125 ? -21.62000 -18.04000 -14.88600 1.000 31.68590  ? 125 VAL A CG1 1 
ATOM   879  C CG2 . VAL A 1 125 ? -20.76100 -16.77300 -12.96500 1.000 37.44452  ? 125 VAL A CG2 1 
ATOM   880  N N   . ARG A 1 126 ? -21.65800 -21.33000 -13.20200 1.000 44.93991  ? 126 ARG A N   1 
ATOM   881  C CA  . ARG A 1 126 ? -22.14900 -22.60500 -13.72800 1.000 47.86145  ? 126 ARG A CA  1 
ATOM   882  C C   . ARG A 1 126 ? -23.35600 -23.10200 -12.94400 1.000 51.11227  ? 126 ARG A C   1 
ATOM   883  O O   . ARG A 1 126 ? -24.28600 -23.67300 -13.52500 1.000 54.27760  ? 126 ARG A O   1 
ATOM   884  C CB  . ARG A 1 126 ? -21.05100 -23.66800 -13.69900 1.000 39.32159  ? 126 ARG A CB  1 
ATOM   885  C CG  . ARG A 1 126 ? -19.82400 -23.31000 -14.46800 1.000 43.50420  ? 126 ARG A CG  1 
ATOM   886  C CD  . ARG A 1 126 ? -18.86600 -24.49100 -14.57600 1.000 47.95970  ? 126 ARG A CD  1 
ATOM   887  N NE  . ARG A 1 126 ? -17.83100 -24.20600 -15.56900 1.000 51.25913  ? 126 ARG A NE  1 
ATOM   888  C CZ  . ARG A 1 126 ? -16.65900 -23.65200 -15.29300 1.000 48.35351  ? 126 ARG A CZ  1 
ATOM   889  N NH1 . ARG A 1 126 ? -16.30600 -23.36400 -14.04900 1.000 52.23328  ? 126 ARG A NH1 1 
ATOM   890  N NH2 . ARG A 1 126 ? -15.81600 -23.38600 -16.28800 1.000 48.27784  ? 126 ARG A NH2 1 
ATOM   891  N N   . ARG A 1 127 ? -23.33800 -22.92700 -11.61700 1.000 49.15396  ? 127 ARG A N   1 
ATOM   892  C CA  . ARG A 1 127 ? -24.46600 -23.33700 -10.78500 1.000 51.45896  ? 127 ARG A CA  1 
ATOM   893  C C   . ARG A 1 127 ? -25.75200 -22.66800 -11.24600 1.000 55.96266  ? 127 ARG A C   1 
ATOM   894  O O   . ARG A 1 127 ? -26.82400 -23.28600 -11.26000 1.000 53.24611  ? 127 ARG A O   1 
ATOM   895  C CB  . ARG A 1 127 ? -24.19400 -22.98000 -9.31800  1.000 56.43887  ? 127 ARG A CB  1 
ATOM   896  C CG  . ARG A 1 127 ? -23.88900 -24.14900 -8.39100  1.000 61.82573  ? 127 ARG A CG  1 
ATOM   897  C CD  . ARG A 1 127 ? -23.55000 -23.68500 -6.95600  1.000 68.35555  ? 127 ARG A CD  1 
ATOM   898  N NE  . ARG A 1 127 ? -24.67600 -23.79300 -6.02600  1.000 73.48698  ? 127 ARG A NE  1 
ATOM   899  C CZ  . ARG A 1 127 ? -24.56700 -23.78600 -4.70000  1.000 69.57398  ? 127 ARG A CZ  1 
ATOM   900  N NH1 . ARG A 1 127 ? -23.39100 -23.67400 -4.10000  1.000 72.48804  ? 127 ARG A NH1 1 
ATOM   901  N NH2 . ARG A 1 127 ? -25.66300 -23.90500 -3.95600  1.000 63.29701  ? 127 ARG A NH2 1 
ATOM   902  N N   . LEU A 1 128 ? -25.65200 -21.40700 -11.64700 1.000 53.62718  ? 128 LEU A N   1 
ATOM   903  C CA  . LEU A 1 128 ? -26.81000 -20.56000 -11.85300 1.000 57.66242  ? 128 LEU A CA  1 
ATOM   904  C C   . LEU A 1 128 ? -27.27000 -20.54500 -13.30000 1.000 62.76192  ? 128 LEU A C   1 
ATOM   905  O O   . LEU A 1 128 ? -28.46900 -20.39400 -13.55700 1.000 61.97052  ? 128 LEU A O   1 
ATOM   906  C CB  . LEU A 1 128 ? -26.48300 -19.13700 -11.38500 1.000 52.23332  ? 128 LEU A CB  1 
ATOM   907  C CG  . LEU A 1 128 ? -27.67600 -18.26600 -11.04000 1.000 47.47264  ? 128 LEU A CG  1 
ATOM   908  C CD1 . LEU A 1 128 ? -28.75900 -19.08600 -10.35200 1.000 52.43399  ? 128 LEU A CD1 1 
ATOM   909  C CD2 . LEU A 1 128 ? -27.19300 -17.17100 -10.14300 1.000 44.45304  ? 128 LEU A CD2 1 
ATOM   910  N N   . VAL A 1 129 ? -26.34600 -20.68200 -14.25400 1.000 59.08628  ? 129 VAL A N   1 
ATOM   911  C CA  . VAL A 1 129 ? -26.75700 -20.79500 -15.64500 1.000 55.47946  ? 129 VAL A CA  1 
ATOM   912  C C   . VAL A 1 129 ? -27.24300 -22.19900 -15.96300 1.000 69.44384  ? 129 VAL A C   1 
ATOM   913  O O   . VAL A 1 129 ? -27.97500 -22.37800 -16.94800 1.000 75.13790  ? 129 VAL A O   1 
ATOM   914  C CB  . VAL A 1 129 ? -25.61200 -20.42000 -16.60000 1.000 58.36988  ? 129 VAL A CB  1 
ATOM   915  C CG1 . VAL A 1 129 ? -24.54800 -21.50800 -16.61500 1.000 57.56839  ? 129 VAL A CG1 1 
ATOM   916  C CG2 . VAL A 1 129 ? -26.14100 -20.17700 -18.01500 1.000 59.90997  ? 129 VAL A CG2 1 
ATOM   917  N N   . SER A 1 130 ? -26.86500 -23.20000 -15.13600 1.000 66.31565  ? 130 SER A N   1 
ATOM   918  C CA  . SER A 1 130 ? -27.09100 -24.62100 -15.40700 1.000 73.44638  ? 130 SER A CA  1 
ATOM   919  C C   . SER A 1 130 ? -28.48100 -24.84700 -15.98200 1.000 79.25552  ? 130 SER A C   1 
ATOM   920  O O   . SER A 1 130 ? -29.47700 -24.39400 -15.39900 1.000 77.39207  ? 130 SER A O   1 
ATOM   921  C CB  . SER A 1 130 ? -26.90700 -25.46800 -14.13900 1.000 70.58662  ? 130 SER A CB  1 
ATOM   922  O OG  . SER A 1 130 ? -27.17100 -26.84300 -14.39900 1.000 66.82608  ? 130 SER A OG  1 
ATOM   923  N N   . PRO A 1 131 ? -28.58700 -25.52000 -17.12500 1.000 82.39212  ? 131 PRO A N   1 
ATOM   924  C CA  . PRO A 1 131 ? -29.90700 -25.82200 -17.66800 1.000 84.84022  ? 131 PRO A CA  1 
ATOM   925  C C   . PRO A 1 131 ? -30.72200 -26.59800 -16.65100 1.000 88.04471  ? 131 PRO A C   1 
ATOM   926  O O   . PRO A 1 131 ? -30.19400 -27.14900 -15.68100 1.000 85.70050  ? 131 PRO A O   1 
ATOM   927  C CB  . PRO A 1 131 ? -29.59900 -26.65800 -18.91200 1.000 83.47251  ? 131 PRO A CB  1 
ATOM   928  C CG  . PRO A 1 131 ? -28.27700 -27.29900 -18.59900 1.000 80.14008  ? 131 PRO A CG  1 
ATOM   929  C CD  . PRO A 1 131 ? -27.52400 -26.25000 -17.82600 1.000 78.01640  ? 131 PRO A CD  1 
ATOM   930  N N   . LEU A 1 132 ? -32.03200 -26.63900 -16.88600 1.000 89.18331  ? 132 LEU A N   1 
ATOM   931  C CA  . LEU A 1 132 ? -32.96300 -27.20600 -15.91500 1.000 91.70621  ? 132 LEU A CA  1 
ATOM   932  C C   . LEU A 1 132 ? -32.81600 -26.47900 -14.57800 1.000 89.37573  ? 132 LEU A C   1 
ATOM   933  O O   . LEU A 1 132 ? -32.62900 -27.08400 -13.51800 1.000 87.13856  ? 132 LEU A O   1 
ATOM   934  C CB  . LEU A 1 132 ? -32.76800 -28.72100 -15.76500 1.000 95.42590  ? 132 LEU A CB  1 
ATOM   935  C CG  . LEU A 1 132 ? -32.95500 -29.57300 -17.03000 1.000 97.15306  ? 132 LEU A CG  1 
ATOM   936  C CD1 . LEU A 1 132 ? -32.46800 -31.00100 -16.79700 1.000 98.73829  ? 132 LEU A CD1 1 
ATOM   937  C CD2 . LEU A 1 132 ? -34.41300 -29.56300 -17.51000 1.000 88.94303  ? 132 LEU A CD2 1 
ATOM   938  N N   . ALA A 1 133 ? -32.85400 -25.15500 -14.65500 1.000 90.71028  ? 133 ALA A N   1 
ATOM   939  C CA  . ALA A 1 133 ? -33.01000 -24.30200 -13.49100 1.000 85.55625  ? 133 ALA A CA  1 
ATOM   940  C C   . ALA A 1 133 ? -34.49600 -24.10500 -13.20900 1.000 88.77189  ? 133 ALA A C   1 
ATOM   941  O O   . ALA A 1 133 ? -35.34300 -24.19600 -14.10400 1.000 83.07691  ? 133 ALA A O   1 
ATOM   942  C CB  . ALA A 1 133 ? -32.32400 -22.95200 -13.70600 1.000 71.11379  ? 133 ALA A CB  1 
ATOM   943  N N   . GLY A 1 134 ? -34.80500 -23.84100 -11.94000 1.000 86.73373  ? 134 GLY A N   1 
ATOM   944  C CA  . GLY A 1 134 ? -36.18400 -23.66600 -11.53800 1.000 74.71346  ? 134 GLY A CA  1 
ATOM   945  C C   . GLY A 1 134 ? -37.00300 -24.93200 -11.48800 1.000 73.12072  ? 134 GLY A C   1 
ATOM   946  O O   . GLY A 1 134 ? -38.21400 -24.84400 -11.27500 1.000 71.97541  ? 134 GLY A O   1 
ATOM   947  N N   . VAL A 1 135 ? -36.37900 -26.10900 -11.65400 1.000 74.25785  ? 135 VAL A N   1 
ATOM   948  C CA  . VAL A 1 135 ? -37.07600 -27.39600 -11.71800 1.000 78.07242  ? 135 VAL A CA  1 
ATOM   949  C C   . VAL A 1 135 ? -37.51500 -27.82500 -10.31400 1.000 80.42479  ? 135 VAL A C   1 
ATOM   950  O O   . VAL A 1 135 ? -37.77500 -29.00800 -10.04700 1.000 80.67796  ? 135 VAL A O   1 
ATOM   951  C CB  . VAL A 1 135 ? -36.19500 -28.45200 -12.42400 1.000 79.31766  ? 135 VAL A CB  1 
ATOM   952  C CG1 . VAL A 1 135 ? -36.95800 -29.76100 -12.71700 1.000 80.89052  ? 135 VAL A CG1 1 
ATOM   953  C CG2 . VAL A 1 135 ? -35.70600 -27.88800 -13.72800 1.000 75.20651  ? 135 VAL A CG2 1 
ATOM   954  N N   . LYS A 1 136 ? -37.59800 -26.85200 -9.40100  1.000 77.07026  ? 136 LYS A N   1 
ATOM   955  C CA  . LYS A 1 136 ? -38.46100 -26.96200 -8.22800  1.000 80.84388  ? 136 LYS A CA  1 
ATOM   956  C C   . LYS A 1 136 ? -38.99400 -25.57800 -7.86600  1.000 78.38861  ? 136 LYS A C   1 
ATOM   957  O O   . LYS A 1 136 ? -39.12600 -25.22700 -6.68600  1.000 76.23422  ? 136 LYS A O   1 
ATOM   958  C CB  . LYS A 1 136 ? -37.74900 -27.62600 -7.04300  1.000 77.89003  ? 136 LYS A CB  1 
ATOM   959  C CG  . LYS A 1 136 ? -38.71500 -28.19400 -6.00500  1.000 75.06367  ? 136 LYS A CG  1 
ATOM   960  C CD  . LYS A 1 136 ? -39.96500 -28.78000 -6.66300  1.000 67.26400  ? 136 LYS A CD  1 
ATOM   961  C CE  . LYS A 1 136 ? -39.70600 -30.15100 -7.25700  1.000 70.68273  ? 136 LYS A CE  1 
ATOM   962  N NZ  . LYS A 1 136 ? -40.93500 -30.99500 -7.19200  1.000 61.76666  ? 136 LYS A NZ  1 
ATOM   963  N N   . GLY A 1 137 ? -39.29600 -24.78400 -8.88800  1.000 73.31581  ? 137 GLY A N   1 
ATOM   964  C CA  . GLY A 1 137 ? -39.88900 -23.46900 -8.78000  1.000 71.03801  ? 137 GLY A CA  1 
ATOM   965  C C   . GLY A 1 137 ? -38.89900 -22.36000 -9.12300  1.000 70.77905  ? 137 GLY A C   1 
ATOM   966  O O   . GLY A 1 137 ? -37.67600 -22.54700 -9.13900  1.000 66.26439  ? 137 GLY A O   1 
ATOM   967  N N   . THR A 1 138 ? -39.45600 -21.18100 -9.42200  1.000 62.89790  ? 138 THR A N   1 
ATOM   968  C CA  . THR A 1 138 ? -38.66900 -19.96600 -9.26800  1.000 56.71929  ? 138 THR A CA  1 
ATOM   969  C C   . THR A 1 138 ? -38.18600 -19.83900 -7.82700  1.000 54.24241  ? 138 THR A C   1 
ATOM   970  O O   . THR A 1 138 ? -37.14000 -19.24400 -7.56100  1.000 51.71862  ? 138 THR A O   1 
ATOM   971  C CB  . THR A 1 138 ? -39.49200 -18.73900 -9.69500  1.000 59.84713  ? 138 THR A CB  1 
ATOM   972  O OG1 . THR A 1 138 ? -40.77800 -18.76400 -9.07000  1.000 54.44608  ? 138 THR A OG1 1 
ATOM   973  C CG2 . THR A 1 138 ? -39.70400 -18.71000 -11.21100 1.000 64.02558  ? 138 THR A CG2 1 
ATOM   974  N N   . GLN A 1 139 ? -38.91400 -20.43800 -6.88900  1.000 58.76638  ? 139 GLN A N   1 
ATOM   975  C CA  . GLN A 1 139 ? -38.50800 -20.39500 -5.49100  1.000 55.96895  ? 139 GLN A CA  1 
ATOM   976  C C   . GLN A 1 139 ? -37.15500 -21.07100 -5.28800  1.000 57.45116  ? 139 GLN A C   1 
ATOM   977  O O   . GLN A 1 139 ? -36.29900 -20.56400 -4.55400  1.000 57.38747  ? 139 GLN A O   1 
ATOM   978  C CB  . GLN A 1 139 ? -39.60000 -21.04300 -4.63300  1.000 60.67823  ? 139 GLN A CB  1 
ATOM   979  C CG  . GLN A 1 139 ? -39.32400 -21.08700 -3.14900  1.000 62.82215  ? 139 GLN A CG  1 
ATOM   980  C CD  . GLN A 1 139 ? -39.08000 -19.71400 -2.55300  1.000 61.13045  ? 139 GLN A CD  1 
ATOM   981  O OE1 . GLN A 1 139 ? -39.76400 -18.74500 -2.89200  1.000 55.21996  ? 139 GLN A OE1 1 
ATOM   982  N NE2 . GLN A 1 139 ? -38.09400 -19.62500 -1.65900  1.000 54.78067  ? 139 GLN A NE2 1 
ATOM   983  N N   . ALA A 1 140 ? -36.93100 -22.21600 -5.92900  1.000 59.07995  ? 140 ALA A N   1 
ATOM   984  C CA  . ALA A 1 140 ? -35.60700 -22.81400 -5.82000  1.000 52.38563  ? 140 ALA A CA  1 
ATOM   985  C C   . ALA A 1 140 ? -34.58000 -22.05100 -6.64400  1.000 45.84680  ? 140 ALA A C   1 
ATOM   986  O O   . ALA A 1 140 ? -33.37500 -22.17000 -6.39800  1.000 40.53427  ? 140 ALA A O   1 
ATOM   987  C CB  . ALA A 1 140 ? -35.65500 -24.28300 -6.23900  1.000 60.12452  ? 140 ALA A CB  1 
ATOM   988  N N   . LEU A 1 141 ? -35.03100 -21.27200 -7.62000  1.000 51.04665  ? 141 LEU A N   1 
ATOM   989  C CA  . LEU A 1 141 ? -34.11500 -20.43400 -8.38600  1.000 53.03538  ? 141 LEU A CA  1 
ATOM   990  C C   . LEU A 1 141 ? -33.55400 -19.31900 -7.51200  1.000 47.47791  ? 141 LEU A C   1 
ATOM   991  O O   . LEU A 1 141 ? -32.34600 -19.06000 -7.50900  1.000 42.14771  ? 141 LEU A O   1 
ATOM   992  C CB  . LEU A 1 141 ? -34.85600 -19.87300 -9.60300  1.000 54.61794  ? 141 LEU A CB  1 
ATOM   993  C CG  . LEU A 1 141 ? -34.15500 -19.18600 -10.76000 1.000 48.11301  ? 141 LEU A CG  1 
ATOM   994  C CD1 . LEU A 1 141 ? -32.77800 -19.77000 -10.94600 1.000 45.84816  ? 141 LEU A CD1 1 
ATOM   995  C CD2 . LEU A 1 141 ? -35.00800 -19.42900 -11.98000 1.000 46.98019  ? 141 LEU A CD2 1 
ATOM   996  N N   . LEU A 1 142 ? -34.42700 -18.66600 -6.74400  1.000 44.66260  ? 142 LEU A N   1 
ATOM   997  C CA  . LEU A 1 142 ? -33.99900 -17.61300 -5.83700  1.000 42.49715  ? 142 LEU A CA  1 
ATOM   998  C C   . LEU A 1 142 ? -33.07400 -18.15800 -4.75300  1.000 40.68282  ? 142 LEU A C   1 
ATOM   999  O O   . LEU A 1 142 ? -32.08500 -17.51100 -4.38300  1.000 42.84444  ? 142 LEU A O   1 
ATOM   1000 C CB  . LEU A 1 142 ? -35.23300 -16.94600 -5.22500  1.000 41.54873  ? 142 LEU A CB  1 
ATOM   1001 C CG  . LEU A 1 142 ? -36.22600 -16.44700 -6.28500  1.000 44.67383  ? 142 LEU A CG  1 
ATOM   1002 C CD1 . LEU A 1 142 ? -37.49800 -15.85000 -5.69500  1.000 38.98563  ? 142 LEU A CD1 1 
ATOM   1003 C CD2 . LEU A 1 142 ? -35.53500 -15.43900 -7.17700  1.000 43.50073  ? 142 LEU A CD2 1 
ATOM   1004 N N   . GLN A 1 143 ? -33.38800 -19.33700 -4.21900  1.000 37.71602  ? 143 GLN A N   1 
ATOM   1005 C CA  . GLN A 1 143 ? -32.58200 -19.89300 -3.13800  1.000 41.93373  ? 143 GLN A CA  1 
ATOM   1006 C C   . GLN A 1 143 ? -31.14500 -20.11300 -3.58400  1.000 42.85225  ? 143 GLN A C   1 
ATOM   1007 O O   . GLN A 1 143 ? -30.20000 -19.89900 -2.81300  1.000 45.30218  ? 143 GLN A O   1 
ATOM   1008 C CB  . GLN A 1 143 ? -33.19500 -21.20400 -2.65200  1.000 41.85860  ? 143 GLN A CB  1 
ATOM   1009 C CG  . GLN A 1 143 ? -32.43800 -21.83000 -1.52000  1.000 38.26483  ? 143 GLN A CG  1 
ATOM   1010 C CD  . GLN A 1 143 ? -32.39800 -20.93800 -0.31200  1.000 41.09672  ? 143 GLN A CD  1 
ATOM   1011 O OE1 . GLN A 1 143 ? -33.23700 -20.05100 -0.16200  1.000 39.34565  ? 143 GLN A OE1 1 
ATOM   1012 N NE2 . GLN A 1 143 ? -31.41600 -21.15800 0.56100   1.000 42.14263  ? 143 GLN A NE2 1 
ATOM   1013 N N   . THR A 1 144 ? -30.97000 -20.53700 -4.83200  1.000 44.83467  ? 144 THR A N   1 
ATOM   1014 C CA  . THR A 1 144 ? -29.64300 -20.71500 -5.40400  1.000 44.05881  ? 144 THR A CA  1 
ATOM   1015 C C   . THR A 1 144 ? -28.94500 -19.37400 -5.60600  1.000 47.25662  ? 144 THR A C   1 
ATOM   1016 O O   . THR A 1 144 ? -27.73200 -19.25800 -5.36900  1.000 45.67095  ? 144 THR A O   1 
ATOM   1017 C CB  . THR A 1 144 ? -29.78000 -21.49400 -6.71400  1.000 44.43258  ? 144 THR A CB  1 
ATOM   1018 O OG1 . THR A 1 144 ? -30.18300 -22.83200 -6.40600  1.000 35.95280  ? 144 THR A OG1 1 
ATOM   1019 C CG2 . THR A 1 144 ? -28.47300 -21.51200 -7.51500  1.000 46.73471  ? 144 THR A CG2 1 
ATOM   1020 N N   . ALA A 1 145 ? -29.69400 -18.34300 -6.01600  1.000 41.29057  ? 145 ALA A N   1 
ATOM   1021 C CA  . ALA A 1 145 ? -29.11000 -17.00700 -6.10100  1.000 41.86171  ? 145 ALA A CA  1 
ATOM   1022 C C   . ALA A 1 145 ? -28.59100 -16.53500 -4.74000  1.000 38.32538  ? 145 ALA A C   1 
ATOM   1023 O O   . ALA A 1 145 ? -27.48600 -15.99100 -4.64800  1.000 37.48883  ? 145 ALA A O   1 
ATOM   1024 C CB  . ALA A 1 145 ? -30.12500 -16.01800 -6.66900  1.000 32.48547  ? 145 ALA A CB  1 
ATOM   1025 N N   . ALA A 1 146 ? -29.35500 -16.74800 -3.66800  1.000 31.19497  ? 146 ALA A N   1 
ATOM   1026 C CA  . ALA A 1 146 ? -28.86700 -16.34200 -2.35400  1.000 36.39223  ? 146 ALA A CA  1 
ATOM   1027 C C   . ALA A 1 146 ? -27.63500 -17.14400 -1.94900  1.000 40.93803  ? 146 ALA A C   1 
ATOM   1028 O O   . ALA A 1 146 ? -26.64700 -16.58000 -1.45900  1.000 37.39570  ? 146 ALA A O   1 
ATOM   1029 C CB  . ALA A 1 146 ? -29.97300 -16.49600 -1.30800  1.000 37.67784  ? 146 ALA A CB  1 
ATOM   1030 N N   . ASP A 1 147 ? -27.67500 -18.46500 -2.16100  1.000 42.80944  ? 147 ASP A N   1 
ATOM   1031 C CA  . ASP A 1 147 ? -26.60900 -19.34700 -1.69400  1.000 38.75361  ? 147 ASP A CA  1 
ATOM   1032 C C   . ASP A 1 147 ? -25.28200 -19.05300 -2.39400  1.000 40.76139  ? 147 ASP A C   1 
ATOM   1033 O O   . ASP A 1 147 ? -24.22600 -19.03900 -1.75400  1.000 40.67603  ? 147 ASP A O   1 
ATOM   1034 C CB  . ASP A 1 147 ? -27.02900 -20.80400 -1.89700  1.000 41.56668  ? 147 ASP A CB  1 
ATOM   1035 C CG  . ASP A 1 147 ? -28.01100 -21.28600 -0.83000  1.000 43.16400  ? 147 ASP A CG  1 
ATOM   1036 O OD1 . ASP A 1 147 ? -27.93100 -20.81400 0.31500   1.000 47.45914  ? 147 ASP A OD1 1 
ATOM   1037 O OD2 . ASP A 1 147 ? -28.85600 -22.15000 -1.11200  1.000 41.34404  ? 147 ASP A OD2 1 
ATOM   1038 N N   . THR A 1 148 ? -25.31100 -18.81100 -3.70400  1.000 39.89036  ? 148 THR A N   1 
ATOM   1039 C CA  . THR A 1 148 ? -24.06400 -18.53200 -4.40900  1.000 45.62478  ? 148 THR A CA  1 
ATOM   1040 C C   . THR A 1 148 ? -23.53200 -17.13900 -4.09300  1.000 42.40320  ? 148 THR A C   1 
ATOM   1041 O O   . THR A 1 148 ? -22.31600 -16.95600 -3.94900  1.000 43.21415  ? 148 THR A O   1 
ATOM   1042 C CB  . THR A 1 148 ? -24.24000 -18.68500 -5.91900  1.000 44.65132  ? 148 THR A CB  1 
ATOM   1043 O OG1 . THR A 1 148 ? -25.08500 -17.63500 -6.41200  1.000 41.29625  ? 148 THR A OG1 1 
ATOM   1044 C CG2 . THR A 1 148 ? -24.82900 -20.05000 -6.24900  1.000 46.19759  ? 148 THR A CG2 1 
ATOM   1045 N N   . VAL A 1 149 ? -24.40600 -16.13200 -4.00800  1.000 41.78390  ? 149 VAL A N   1 
ATOM   1046 C CA  . VAL A 1 149 ? -23.91200 -14.81700 -3.60400  1.000 38.84297  ? 149 VAL A CA  1 
ATOM   1047 C C   . VAL A 1 149 ? -23.30900 -14.89700 -2.20700  1.000 39.00794  ? 149 VAL A C   1 
ATOM   1048 O O   . VAL A 1 149 ? -22.28500 -14.26500 -1.91700  1.000 39.78154  ? 149 VAL A O   1 
ATOM   1049 C CB  . VAL A 1 149 ? -25.01900 -13.75300 -3.69000  1.000 33.29691  ? 149 VAL A CB  1 
ATOM   1050 C CG1 . VAL A 1 149 ? -24.68200 -12.57600 -2.78000  1.000 39.06807  ? 149 VAL A CG1 1 
ATOM   1051 C CG2 . VAL A 1 149 ? -25.16000 -13.25600 -5.11600  1.000 33.13861  ? 149 VAL A CG2 1 
ATOM   1052 N N   . ARG A 1 150 ? -23.90200 -15.70900 -1.33200  1.000 36.81465  ? 150 ARG A N   1 
ATOM   1053 C CA  . ARG A 1 150 ? -23.30000 -15.89200 -0.02000  1.000 39.95802  ? 150 ARG A CA  1 
ATOM   1054 C C   . ARG A 1 150 ? -21.97300 -16.63700 -0.11500  1.000 39.09658  ? 150 ARG A C   1 
ATOM   1055 O O   . ARG A 1 150 ? -21.05000 -16.35500 0.65600   1.000 39.19413  ? 150 ARG A O   1 
ATOM   1056 C CB  . ARG A 1 150 ? -24.26000 -16.62100 0.91000   1.000 38.76057  ? 150 ARG A CB  1 
ATOM   1057 C CG  . ARG A 1 150 ? -23.69800 -16.74300 2.29400   1.000 41.74912  ? 150 ARG A CG  1 
ATOM   1058 C CD  . ARG A 1 150 ? -24.77100 -16.95500 3.35200   1.000 44.29037  ? 150 ARG A CD  1 
ATOM   1059 N NE  . ARG A 1 150 ? -24.16500 -17.66500 4.47000   1.000 50.51111  ? 150 ARG A NE  1 
ATOM   1060 C CZ  . ARG A 1 150 ? -24.03200 -18.98300 4.51100   1.000 51.03811  ? 150 ARG A CZ  1 
ATOM   1061 N NH1 . ARG A 1 150 ? -24.61100 -19.76800 3.60800   1.000 45.71035  ? 150 ARG A NH1 1 
ATOM   1062 N NH2 . ARG A 1 150 ? -23.27800 -19.52700 5.46100   1.000 52.60246  ? 150 ARG A NH2 1 
ATOM   1063 N N   . ALA A 1 151 ? -21.85900 -17.59000 -1.05000  1.000 41.45180  ? 151 ALA A N   1 
ATOM   1064 C CA  . ALA A 1 151 ? -20.61200 -18.33600 -1.20300  1.000 38.66862  ? 151 ALA A CA  1 
ATOM   1065 C C   . ALA A 1 151 ? -19.50800 -17.44400 -1.73400  1.000 42.02122  ? 151 ALA A C   1 
ATOM   1066 O O   . ALA A 1 151 ? -18.36400 -17.52300 -1.27000  1.000 46.55242  ? 151 ALA A O   1 
ATOM   1067 C CB  . ALA A 1 151 ? -20.80800 -19.53200 -2.12900  1.000 32.90660  ? 151 ALA A CB  1 
ATOM   1068 N N   . LEU A 1 152 ? -19.83800 -16.56700 -2.69100  1.000 43.11230  ? 152 LEU A N   1 
ATOM   1069 C CA  . LEU A 1 152 ? -18.83100 -15.72400 -3.32800  1.000 37.42892  ? 152 LEU A CA  1 
ATOM   1070 C C   . LEU A 1 152 ? -18.37700 -14.56800 -2.43600  1.000 43.29527  ? 152 LEU A C   1 
ATOM   1071 O O   . LEU A 1 152 ? -17.24200 -14.08700 -2.58800  1.000 40.65775  ? 152 LEU A O   1 
ATOM   1072 C CB  . LEU A 1 152 ? -19.37100 -15.18900 -4.65100  1.000 33.76362  ? 152 LEU A CB  1 
ATOM   1073 C CG  . LEU A 1 152 ? -18.33500 -14.43900 -5.47900  1.000 36.10134  ? 152 LEU A CG  1 
ATOM   1074 C CD1 . LEU A 1 152 ? -17.08800 -15.28100 -5.57400  1.000 39.23856  ? 152 LEU A CD1 1 
ATOM   1075 C CD2 . LEU A 1 152 ? -18.86100 -14.10200 -6.86100  1.000 38.93660  ? 152 LEU A CD2 1 
ATOM   1076 N N   . THR A 1 153 ? -19.22700 -14.12000 -1.49700  1.000 44.01389  ? 153 THR A N   1 
ATOM   1077 C CA  . THR A 1 153 ? -18.95900 -12.94500 -0.66400  1.000 39.42365  ? 153 THR A CA  1 
ATOM   1078 C C   . THR A 1 153 ? -18.64900 -13.25900 0.79100   1.000 40.71688  ? 153 THR A C   1 
ATOM   1079 O O   . THR A 1 153 ? -17.99000 -12.45700 1.45300   1.000 45.33633  ? 153 THR A O   1 
ATOM   1080 C CB  . THR A 1 153 ? -20.15400 -11.98500 -0.67700  1.000 37.51677  ? 153 THR A CB  1 
ATOM   1081 O OG1 . THR A 1 153 ? -21.27900 -12.62200 -0.06500  1.000 39.64717  ? 153 THR A OG1 1 
ATOM   1082 C CG2 . THR A 1 153 ? -20.50600 -11.62600 -2.08400  1.000 40.25012  ? 153 THR A CG2 1 
ATOM   1083 N N   . GLY A 1 154 ? -19.13300 -14.37400 1.32200   1.000 41.51401  ? 154 GLY A N   1 
ATOM   1084 C CA  . GLY A 1 154 ? -18.88200 -14.69300 2.71000   1.000 38.69409  ? 154 GLY A CA  1 
ATOM   1085 C C   . GLY A 1 154 ? -19.70100 -13.92100 3.72100   1.000 38.70056  ? 154 GLY A C   1 
ATOM   1086 O O   . GLY A 1 154 ? -19.36900 -13.95500 4.91000   1.000 41.63159  ? 154 GLY A O   1 
ATOM   1087 N N   . PHE A 1 155 ? -20.76800 -13.24300 3.30600   1.000 39.72251  ? 155 PHE A N   1 
ATOM   1088 C CA  . PHE A 1 155 ? -21.59200 -12.51100 4.26300   1.000 40.33488  ? 155 PHE A CA  1 
ATOM   1089 C C   . PHE A 1 155 ? -22.39400 -13.46300 5.15900   1.000 43.21137  ? 155 PHE A C   1 
ATOM   1090 O O   . PHE A 1 155 ? -22.73900 -14.59400 4.78100   1.000 36.71289  ? 155 PHE A O   1 
ATOM   1091 C CB  . PHE A 1 155 ? -22.53900 -11.55500 3.53800   1.000 36.65470  ? 155 PHE A CB  1 
ATOM   1092 C CG  . PHE A 1 155 ? -21.96700 -10.17800 3.30900   1.000 36.38324  ? 155 PHE A CG  1 
ATOM   1093 C CD1 . PHE A 1 155 ? -20.86300 -10.00100 2.50000   1.000 37.84007  ? 155 PHE A CD1 1 
ATOM   1094 C CD2 . PHE A 1 155 ? -22.55700 -9.05700  3.88400   1.000 35.58865  ? 155 PHE A CD2 1 
ATOM   1095 C CE1 . PHE A 1 155 ? -20.34200 -8.73300  2.28500   1.000 40.11338  ? 155 PHE A CE1 1 
ATOM   1096 C CE2 . PHE A 1 155 ? -22.03500 -7.77500  3.66400   1.000 33.61683  ? 155 PHE A CE2 1 
ATOM   1097 C CZ  . PHE A 1 155 ? -20.92500 -7.61600  2.86500   1.000 30.21023  ? 155 PHE A CZ  1 
ATOM   1098 N N   . ASP A 1 156 ? -22.68500 -12.98900 6.37200   1.000 39.48619  ? 156 ASP A N   1 
ATOM   1099 C CA  . ASP A 1 156 ? -23.41500 -13.81200 7.32700   1.000 45.41226  ? 156 ASP A CA  1 
ATOM   1100 C C   . ASP A 1 156 ? -24.84200 -14.09300 6.86400   1.000 47.38488  ? 156 ASP A C   1 
ATOM   1101 O O   . ASP A 1 156 ? -25.39300 -15.16100 7.15900   1.000 48.65932  ? 156 ASP A O   1 
ATOM   1102 C CB  . ASP A 1 156 ? -23.41600 -13.13000 8.68800   1.000 41.63388  ? 156 ASP A CB  1 
ATOM   1103 C CG  . ASP A 1 156 ? -22.05100 -13.13500 9.33300   1.000 45.95403  ? 156 ASP A CG  1 
ATOM   1104 O OD1 . ASP A 1 156 ? -21.30600 -14.12200 9.12700   1.000 44.89670  ? 156 ASP A OD1 1 
ATOM   1105 O OD2 . ASP A 1 156 ? -21.72200 -12.14800 10.03100  1.000 46.05756  ? 156 ASP A OD2 1 
ATOM   1106 N N   . ARG A 1 157 ? -25.45500 -13.16400 6.14400   1.000 36.71168  ? 157 ARG A N   1 
ATOM   1107 C CA  . ARG A 1 157 ? -26.82600 -13.34600 5.70600   1.000 39.00541  ? 157 ARG A CA  1 
ATOM   1108 C C   . ARG A 1 157 ? -26.98100 -12.67500 4.35400   1.000 39.92306  ? 157 ARG A C   1 
ATOM   1109 O O   . ARG A 1 157 ? -26.57100 -11.52400 4.17900   1.000 40.12298  ? 157 ARG A O   1 
ATOM   1110 C CB  . ARG A 1 157 ? -27.79900 -12.74900 6.72800   1.000 42.18108  ? 157 ARG A CB  1 
ATOM   1111 C CG  . ARG A 1 157 ? -29.27800 -12.89300 6.41700   1.000 38.87327  ? 157 ARG A CG  1 
ATOM   1112 C CD  . ARG A 1 157 ? -30.11100 -12.48000 7.62500   1.000 41.11096  ? 157 ARG A CD  1 
ATOM   1113 N NE  . ARG A 1 157 ? -29.80500 -11.12900 8.08800   1.000 40.38762  ? 157 ARG A NE  1 
ATOM   1114 C CZ  . ARG A 1 157 ? -29.90400 -10.71500 9.34900   1.000 43.09666  ? 157 ARG A CZ  1 
ATOM   1115 N NH1 . ARG A 1 157 ? -30.23500 -11.53900 10.33000  1.000 42.14552  ? 157 ARG A NH1 1 
ATOM   1116 N NH2 . ARG A 1 157 ? -29.66500 -9.43600  9.63300   1.000 45.32404  ? 157 ARG A NH2 1 
ATOM   1117 N N   . VAL A 1 158 ? -27.55600 -13.40300 3.40800   1.000 38.52840  ? 158 VAL A N   1 
ATOM   1118 C CA  . VAL A 1 158 ? -27.87200 -12.89300 2.08100   1.000 34.29637  ? 158 VAL A CA  1 
ATOM   1119 C C   . VAL A 1 158 ? -29.35700 -13.15000 1.84900   1.000 33.52458  ? 158 VAL A C   1 
ATOM   1120 O O   . VAL A 1 158 ? -29.84000 -14.27200 2.05300   1.000 36.89853  ? 158 VAL A O   1 
ATOM   1121 C CB  . VAL A 1 158 ? -27.00500 -13.56500 0.99300   1.000 35.27613  ? 158 VAL A CB  1 
ATOM   1122 C CG1 . VAL A 1 158 ? -27.43800 -13.14500 -0.40500  1.000 34.44313  ? 158 VAL A CG1 1 
ATOM   1123 C CG2 . VAL A 1 158 ? -25.52900 -13.25900 1.20700   1.000 36.15728  ? 158 VAL A CG2 1 
ATOM   1124 N N   . MET A 1 159 ? -30.08300 -12.11500 1.46300   1.000 32.00991  ? 159 MET A N   1 
ATOM   1125 C CA  . MET A 1 159 ? -31.52600 -12.19800 1.31000   1.000 35.86506  ? 159 MET A CA  1 
ATOM   1126 C C   . MET A 1 159 ? -31.91800 -11.83000 -0.10800  1.000 36.90550  ? 159 MET A C   1 
ATOM   1127 O O   . MET A 1 159 ? -31.17500 -11.14400 -0.81600  1.000 38.68250  ? 159 MET A O   1 
ATOM   1128 C CB  . MET A 1 159 ? -32.22700 -11.26900 2.28900   1.000 32.22970  ? 159 MET A CB  1 
ATOM   1129 C CG  . MET A 1 159 ? -32.09500 -11.72200 3.70400   1.000 38.51087  ? 159 MET A CG  1 
ATOM   1130 S SD  . MET A 1 159 ? -32.11100 -10.29600 4.77300   1.000 48.45348  ? 159 MET A SD  1 
ATOM   1131 C CE  . MET A 1 159 ? -30.60600 -9.47200  4.24700   1.000 34.77051  ? 159 MET A CE  1 
ATOM   1132 N N   . VAL A 1 160 ? -33.09800 -12.28100 -0.52700  1.000 35.89818  ? 160 VAL A N   1 
ATOM   1133 C CA  . VAL A 1 160 ? -33.64300 -11.88100 -1.81900  1.000 34.36315  ? 160 VAL A CA  1 
ATOM   1134 C C   . VAL A 1 160 ? -34.94700 -11.13600 -1.56900  1.000 37.09415  ? 160 VAL A C   1 
ATOM   1135 O O   . VAL A 1 160 ? -35.88100 -11.67400 -0.96000  1.000 33.02907  ? 160 VAL A O   1 
ATOM   1136 C CB  . VAL A 1 160 ? -33.83800 -13.06400 -2.77700  1.000 33.22980  ? 160 VAL A CB  1 
ATOM   1137 C CG1 . VAL A 1 160 ? -34.47800 -12.57500 -4.07800  1.000 31.28079  ? 160 VAL A CG1 1 
ATOM   1138 C CG2 . VAL A 1 160 ? -32.50100 -13.67900 -3.08700  1.000 31.68036  ? 160 VAL A CG2 1 
ATOM   1139 N N   . TYR A 1 161 ? -35.00200 -9.89900  -2.04600  1.000 32.40206  ? 161 TYR A N   1 
ATOM   1140 C CA  . TYR A 1 161 ? -36.02700 -8.93900  -1.68200  1.000 35.55046  ? 161 TYR A CA  1 
ATOM   1141 C C   . TYR A 1 161 ? -36.77100 -8.55700  -2.94900  1.000 37.70830  ? 161 TYR A C   1 
ATOM   1142 O O   . TYR A 1 161 ? -36.14700 -8.08900  -3.91000  1.000 38.76345  ? 161 TYR A O   1 
ATOM   1143 C CB  . TYR A 1 161 ? -35.36800 -7.71200  -1.04100  1.000 32.91880  ? 161 TYR A CB  1 
ATOM   1144 C CG  . TYR A 1 161 ? -36.29800 -6.70400  -0.40900  1.000 31.61330  ? 161 TYR A CG  1 
ATOM   1145 C CD1 . TYR A 1 161 ? -36.95300 -7.00100  0.78000   1.000 33.04357  ? 161 TYR A CD1 1 
ATOM   1146 C CD2 . TYR A 1 161 ? -36.48300 -5.44200  -0.97100  1.000 31.24893  ? 161 TYR A CD2 1 
ATOM   1147 C CE1 . TYR A 1 161 ? -37.78600 -6.08700  1.39200   1.000 37.02608  ? 161 TYR A CE1 1 
ATOM   1148 C CE2 . TYR A 1 161 ? -37.32900 -4.50600  -0.36300  1.000 37.61451  ? 161 TYR A CE2 1 
ATOM   1149 C CZ  . TYR A 1 161 ? -37.97700 -4.84200  0.82600   1.000 35.88674  ? 161 TYR A CZ  1 
ATOM   1150 O OH  . TYR A 1 161 ? -38.81900 -3.95400  1.46200   1.000 33.57796  ? 161 TYR A OH  1 
ATOM   1151 N N   . ARG A 1 162 ? -38.08900 -8.76100  -2.96700  1.000 37.90007  ? 162 ARG A N   1 
ATOM   1152 C CA  . ARG A 1 162 ? -38.89000 -8.37000  -4.12200  1.000 33.60674  ? 162 ARG A CA  1 
ATOM   1153 C C   . ARG A 1 162 ? -39.78400 -7.19100  -3.76800  1.000 34.18563  ? 162 ARG A C   1 
ATOM   1154 O O   . ARG A 1 162 ? -40.36300 -7.13700  -2.67500  1.000 36.99943  ? 162 ARG A O   1 
ATOM   1155 C CB  . ARG A 1 162 ? -39.74400 -9.51900  -4.66100  1.000 31.92555  ? 162 ARG A CB  1 
ATOM   1156 C CG  . ARG A 1 162 ? -40.52700 -9.09100  -5.90500  1.000 38.03720  ? 162 ARG A CG  1 
ATOM   1157 C CD  . ARG A 1 162 ? -41.61000 -10.04300 -6.28800  1.000 37.10622  ? 162 ARG A CD  1 
ATOM   1158 N NE  . ARG A 1 162 ? -42.35700 -10.52200 -5.13500  1.000 42.92842  ? 162 ARG A NE  1 
ATOM   1159 C CZ  . ARG A 1 162 ? -43.16500 -11.57500 -5.16800  1.000 51.45891  ? 162 ARG A CZ  1 
ATOM   1160 N NH1 . ARG A 1 162 ? -43.39000 -12.23700 -6.29500  1.000 51.60165  ? 162 ARG A NH1 1 
ATOM   1161 N NH2 . ARG A 1 162 ? -43.74600 -11.98500 -4.04100  1.000 47.15876  ? 162 ARG A NH2 1 
ATOM   1162 N N   . PHE A 1 163 ? -39.87600 -6.23900  -4.69400  1.000 31.14390  ? 163 PHE A N   1 
ATOM   1163 C CA  . PHE A 1 163 ? -40.73800 -5.08500  -4.51900  1.000 35.94395  ? 163 PHE A CA  1 
ATOM   1164 C C   . PHE A 1 163 ? -42.15500 -5.41000  -4.96000  1.000 41.38906  ? 163 PHE A C   1 
ATOM   1165 O O   . PHE A 1 163 ? -42.36700 -6.04500  -5.99900  1.000 36.47278  ? 163 PHE A O   1 
ATOM   1166 C CB  . PHE A 1 163 ? -40.21300 -3.89800  -5.32400  1.000 36.61164  ? 163 PHE A CB  1 
ATOM   1167 C CG  . PHE A 1 163 ? -39.02800 -3.23200  -4.70900  1.000 34.43608  ? 163 PHE A CG  1 
ATOM   1168 C CD1 . PHE A 1 163 ? -39.14800 -2.57200  -3.49900  1.000 36.16388  ? 163 PHE A CD1 1 
ATOM   1169 C CD2 . PHE A 1 163 ? -37.79500 -3.25700  -5.34600  1.000 35.53005  ? 163 PHE A CD2 1 
ATOM   1170 C CE1 . PHE A 1 163 ? -38.05700 -1.95500  -2.92300  1.000 35.88388  ? 163 PHE A CE1 1 
ATOM   1171 C CE2 . PHE A 1 163 ? -36.69000 -2.64000  -4.78600  1.000 34.41803  ? 163 PHE A CE2 1 
ATOM   1172 C CZ  . PHE A 1 163 ? -36.82000 -1.98200  -3.57000  1.000 36.45205  ? 163 PHE A CZ  1 
ATOM   1173 N N   . ASP A 1 164 ? -43.12500 -4.96400  -4.17100  1.000 43.37023  ? 164 ASP A N   1 
ATOM   1174 C CA  . ASP A 1 164 ? -44.52000 -5.08400  -4.55200  1.000 40.48116  ? 164 ASP A CA  1 
ATOM   1175 C C   . ASP A 1 164 ? -44.92200 -3.85500  -5.36900  1.000 46.24270  ? 164 ASP A C   1 
ATOM   1176 O O   . ASP A 1 164 ? -44.09900 -2.98400  -5.67100  1.000 44.44482  ? 164 ASP A O   1 
ATOM   1177 C CB  . ASP A 1 164 ? -45.38300 -5.28300  -3.30900  1.000 44.43063  ? 164 ASP A CB  1 
ATOM   1178 C CG  . ASP A 1 164 ? -46.75500 -5.86100  -3.64200  1.000 57.45319  ? 164 ASP A CG  1 
ATOM   1179 O OD1 . ASP A 1 164 ? -47.51600 -5.20500  -4.39600  1.000 54.53437  ? 164 ASP A OD1 1 
ATOM   1180 O OD2 . ASP A 1 164 ? -47.05900 -6.98600  -3.17900  1.000 63.65045  ? 164 ASP A OD2 1 
ATOM   1181 N N   . ALA A 1 165 ? -46.20800 -3.77000  -5.72900  1.000 46.80042  ? 165 ALA A N   1 
ATOM   1182 C CA  . ALA A 1 165 ? -46.65900 -2.69900  -6.60900  1.000 45.65964  ? 165 ALA A CA  1 
ATOM   1183 C C   . ALA A 1 165 ? -46.67200 -1.35400  -5.89900  1.000 48.05952  ? 165 ALA A C   1 
ATOM   1184 O O   . ALA A 1 165 ? -46.54500 -0.31300  -6.55500  1.000 55.59376  ? 165 ALA A O   1 
ATOM   1185 C CB  . ALA A 1 165 ? -48.04500 -3.02000  -7.17100  1.000 35.59362  ? 165 ALA A CB  1 
ATOM   1186 N N   . ASP A 1 166 ? -46.82700 -1.35000  -4.57600  1.000 43.99204  ? 166 ASP A N   1 
ATOM   1187 C CA  . ASP A 1 166 ? -46.74900 -0.12700  -3.78700  1.000 46.02627  ? 166 ASP A CA  1 
ATOM   1188 C C   . ASP A 1 166 ? -45.33300 0.17300   -3.29300  1.000 45.87647  ? 166 ASP A C   1 
ATOM   1189 O O   . ASP A 1 166 ? -45.13800 1.16400   -2.57800  1.000 45.22839  ? 166 ASP A O   1 
ATOM   1190 C CB  . ASP A 1 166 ? -47.71100 -0.21200  -2.59700  1.000 44.13006  ? 166 ASP A CB  1 
ATOM   1191 C CG  . ASP A 1 166 ? -47.51900 -1.48100  -1.78000  1.000 49.72365  ? 166 ASP A CG  1 
ATOM   1192 O OD1 . ASP A 1 166 ? -46.73500 -2.35300  -2.21900  1.000 45.47978  ? 166 ASP A OD1 1 
ATOM   1193 O OD2 . ASP A 1 166 ? -48.14900 -1.60200  -0.70200  1.000 52.87518  ? 166 ASP A OD2 1 
ATOM   1194 N N   . TRP A 1 167 ? -44.35100 -0.65600  -3.66100  1.000 46.30726  ? 167 TRP A N   1 
ATOM   1195 C CA  . TRP A 1 167 ? -42.92900 -0.52100  -3.33700  1.000 43.10120  ? 167 TRP A CA  1 
ATOM   1196 C C   . TRP A 1 167 ? -42.60800 -0.86500  -1.89300  1.000 44.74639  ? 167 TRP A C   1 
ATOM   1197 O O   . TRP A 1 167 ? -41.49700 -0.57400  -1.43100  1.000 41.14609  ? 167 TRP A O   1 
ATOM   1198 C CB  . TRP A 1 167 ? -42.37700 0.87400   -3.64700  1.000 38.21188  ? 167 TRP A CB  1 
ATOM   1199 C CG  . TRP A 1 167 ? -42.50200 1.21900   -5.07800  1.000 41.52914  ? 167 TRP A CG  1 
ATOM   1200 C CD1 . TRP A 1 167 ? -43.43700 2.03200   -5.64700  1.000 41.57157  ? 167 TRP A CD1 1 
ATOM   1201 C CD2 . TRP A 1 167 ? -41.68600 0.73000   -6.14800  1.000 44.85596  ? 167 TRP A CD2 1 
ATOM   1202 N NE1 . TRP A 1 167 ? -43.25100 2.08500   -7.00000  1.000 35.76165  ? 167 TRP A NE1 1 
ATOM   1203 C CE2 . TRP A 1 167 ? -42.17700 1.30100   -7.33700  1.000 37.97175  ? 167 TRP A CE2 1 
ATOM   1204 C CE3 . TRP A 1 167 ? -40.58100 -0.13400  -6.21500  1.000 41.43102  ? 167 TRP A CE3 1 
ATOM   1205 C CZ2 . TRP A 1 167 ? -41.59300 1.04900   -8.58600  1.000 35.51252  ? 167 TRP A CZ2 1 
ATOM   1206 C CZ3 . TRP A 1 167 ? -40.01500 -0.39500  -7.45100  1.000 36.51312  ? 167 TRP A CZ3 1 
ATOM   1207 C CH2 . TRP A 1 167 ? -40.52500 0.19300   -8.62200  1.000 35.37423  ? 167 TRP A CH2 1 
ATOM   1208 N N   . HIS A 1 168 ? -43.53700 -1.46200  -1.15700  1.000 44.10559  ? 168 HIS A N   1 
ATOM   1209 C CA  . HIS A 1 168 ? -43.08100 -2.23000  -0.01700  1.000 37.39951  ? 168 HIS A CA  1 
ATOM   1210 C C   . HIS A 1 168 ? -42.55600 -3.57100  -0.53700  1.000 36.37595  ? 168 HIS A C   1 
ATOM   1211 O O   . HIS A 1 168 ? -42.73600 -3.91600  -1.70400  1.000 43.97393  ? 168 HIS A O   1 
ATOM   1212 C CB  . HIS A 1 168 ? -44.20700 -2.37900  1.00500   1.000 39.96367  ? 168 HIS A CB  1 
ATOM   1213 C CG  . HIS A 1 168 ? -44.92000 -3.68800  0.93400   1.000 46.41846  ? 168 HIS A CG  1 
ATOM   1214 N ND1 . HIS A 1 168 ? -45.96400 -3.92300  0.06000   1.000 45.81133  ? 168 HIS A ND1 1 
ATOM   1215 C CD2 . HIS A 1 168 ? -44.73500 -4.84000  1.62800   1.000 40.67610  ? 168 HIS A CD2 1 
ATOM   1216 C CE1 . HIS A 1 168 ? -46.39100 -5.16600  0.22200   1.000 46.90879  ? 168 HIS A CE1 1 
ATOM   1217 N NE2 . HIS A 1 168 ? -45.66200 -5.74300  1.16700   1.000 39.82684  ? 168 HIS A NE2 1 
ATOM   1218 N N   . GLY A 1 169 ? -41.86200 -4.32900  0.31100   1.000 37.78530  ? 169 GLY A N   1 
ATOM   1219 C CA  . GLY A 1 169 ? -41.16300 -5.51000  -0.14500  1.000 32.41862  ? 169 GLY A CA  1 
ATOM   1220 C C   . GLY A 1 169 ? -41.36200 -6.70200  0.77400   1.000 35.56075  ? 169 GLY A C   1 
ATOM   1221 O O   . GLY A 1 169 ? -41.95200 -6.60200  1.84500   1.000 37.18598  ? 169 GLY A O   1 
ATOM   1222 N N   . GLU A 1 170 ? -40.87200 -7.84700  0.31400   1.000 39.19392  ? 170 GLU A N   1 
ATOM   1223 C CA  . GLU A 1 170 ? -40.77000 -8.99200  1.19800   1.000 39.39020  ? 170 GLU A CA  1 
ATOM   1224 C C   . GLU A 1 170 ? -39.55600 -9.81900  0.81500   1.000 42.12177  ? 170 GLU A C   1 
ATOM   1225 O O   . GLU A 1 170 ? -39.15300 -9.86600  -0.35300  1.000 35.56834  ? 170 GLU A O   1 
ATOM   1226 C CB  . GLU A 1 170 ? -42.02400 -9.85700  1.16900   1.000 40.18654  ? 170 GLU A CB  1 
ATOM   1227 C CG  . GLU A 1 170 ? -42.39700 -10.37100 -0.18100  1.000 42.99206  ? 170 GLU A CG  1 
ATOM   1228 C CD  . GLU A 1 170 ? -43.60700 -11.27800 -0.10400  1.000 51.01474  ? 170 GLU A CD  1 
ATOM   1229 O OE1 . GLU A 1 170 ? -43.63700 -12.14000 0.80900   1.000 50.44955  ? 170 GLU A OE1 1 
ATOM   1230 O OE2 . GLU A 1 170 ? -44.52700 -11.11300 -0.93800  1.000 53.86517  ? 170 GLU A OE2 1 
ATOM   1231 N N   . VAL A 1 171 ? -38.96200 -10.44500 1.82600   1.000 39.66027  ? 171 VAL A N   1 
ATOM   1232 C CA  . VAL A 1 171 ? -37.85300 -11.36200 1.62100   1.000 37.78358  ? 171 VAL A CA  1 
ATOM   1233 C C   . VAL A 1 171 ? -38.44300 -12.68100 1.14300   1.000 39.35493  ? 171 VAL A C   1 
ATOM   1234 O O   . VAL A 1 171 ? -39.06900 -13.39700 1.92900   1.000 36.68762  ? 171 VAL A O   1 
ATOM   1235 C CB  . VAL A 1 171 ? -37.04300 -11.55800 2.90300   1.000 33.28090  ? 171 VAL A CB  1 
ATOM   1236 C CG1 . VAL A 1 171 ? -36.05200 -12.71200 2.71600   1.000 38.55401  ? 171 VAL A CG1 1 
ATOM   1237 C CG2 . VAL A 1 171 ? -36.33100 -10.28300 3.26500   1.000 27.50607  ? 171 VAL A CG2 1 
ATOM   1238 N N   . LEU A 1 172 ? -38.23900 -13.00200 -0.14800  1.000 41.02218  ? 172 LEU A N   1 
ATOM   1239 C CA  . LEU A 1 172 ? -38.72600 -14.25800 -0.72300  1.000 34.24368  ? 172 LEU A CA  1 
ATOM   1240 C C   . LEU A 1 172 ? -37.78600 -15.42900 -0.47000  1.000 41.67361  ? 172 LEU A C   1 
ATOM   1241 O O   . LEU A 1 172 ? -38.24600 -16.57700 -0.43100  1.000 44.12970  ? 172 LEU A O   1 
ATOM   1242 C CB  . LEU A 1 172 ? -38.94300 -14.11400 -2.22400  1.000 37.74511  ? 172 LEU A CB  1 
ATOM   1243 C CG  . LEU A 1 172 ? -40.01400 -13.11800 -2.66000  1.000 40.01900  ? 172 LEU A CG  1 
ATOM   1244 C CD1 . LEU A 1 172 ? -39.98200 -12.94600 -4.16100  1.000 38.55897  ? 172 LEU A CD1 1 
ATOM   1245 C CD2 . LEU A 1 172 ? -41.37400 -13.58900 -2.19500  1.000 38.43852  ? 172 LEU A CD2 1 
ATOM   1246 N N   . ALA A 1 173 ? -36.48600 -15.17600 -0.29500  1.000 36.58306  ? 173 ALA A N   1 
ATOM   1247 C CA  . ALA A 1 173 ? -35.52100 -16.25300 -0.10100  1.000 35.48465  ? 173 ALA A CA  1 
ATOM   1248 C C   . ALA A 1 173 ? -34.38400 -15.77800 0.80000   1.000 35.94612  ? 173 ALA A C   1 
ATOM   1249 O O   . ALA A 1 173 ? -34.15100 -14.57800 0.96600   1.000 35.62459  ? 173 ALA A O   1 
ATOM   1250 C CB  . ALA A 1 173 ? -34.96800 -16.75200 -1.44300  1.000 35.70783  ? 173 ALA A CB  1 
ATOM   1251 N N   . GLU A 1 174 ? -33.64900 -16.73600 1.35600   1.000 37.36247  ? 174 GLU A N   1 
ATOM   1252 C CA  . GLU A 1 174 ? -32.63200 -16.37900 2.33700   1.000 39.38420  ? 174 GLU A CA  1 
ATOM   1253 C C   . GLU A 1 174 ? -31.58600 -17.47600 2.46600   1.000 41.89673  ? 174 GLU A C   1 
ATOM   1254 O O   . GLU A 1 174 ? -31.92400 -18.65700 2.61800   1.000 37.49685  ? 174 GLU A O   1 
ATOM   1255 C CB  . GLU A 1 174 ? -33.28300 -16.13200 3.68400   1.000 40.61403  ? 174 GLU A CB  1 
ATOM   1256 C CG  . GLU A 1 174 ? -32.49500 -15.30100 4.61600   1.000 43.14643  ? 174 GLU A CG  1 
ATOM   1257 C CD  . GLU A 1 174 ? -33.30100 -15.00200 5.82600   1.000 40.18028  ? 174 GLU A CD  1 
ATOM   1258 O OE1 . GLU A 1 174 ? -33.76500 -15.97000 6.46200   1.000 40.51427  ? 174 GLU A OE1 1 
ATOM   1259 O OE2 . GLU A 1 174 ? -33.49800 -13.81000 6.11900   1.000 42.48851  ? 174 GLU A OE2 1 
ATOM   1260 N N   . SER A 1 175 ? -30.32500 -17.07800 2.38300   1.000 36.77113  ? 175 SER A N   1 
ATOM   1261 C CA  . SER A 1 175 ? -29.20600 -17.93300 2.74100   1.000 39.13049  ? 175 SER A CA  1 
ATOM   1262 C C   . SER A 1 175 ? -28.42200 -17.23100 3.83300   1.000 42.61803  ? 175 SER A C   1 
ATOM   1263 O O   . SER A 1 175 ? -27.93600 -16.11500 3.62900   1.000 40.94174  ? 175 SER A O   1 
ATOM   1264 C CB  . SER A 1 175 ? -28.30100 -18.21100 1.54900   1.000 36.39895  ? 175 SER A CB  1 
ATOM   1265 O OG  . SER A 1 175 ? -27.14200 -18.89300 1.98600   1.000 36.23830  ? 175 SER A OG  1 
ATOM   1266 N N   . LYS A 1 176 ? -28.31000 -17.87500 4.98800   1.000 42.32239  ? 176 LYS A N   1 
ATOM   1267 C CA  . LYS A 1 176 ? -27.58600 -17.30200 6.10700   1.000 47.36564  ? 176 LYS A CA  1 
ATOM   1268 C C   . LYS A 1 176 ? -26.79800 -18.40100 6.79900   1.000 47.90361  ? 176 LYS A C   1 
ATOM   1269 O O   . LYS A 1 176 ? -27.23500 -19.55000 6.86800   1.000 48.59365  ? 176 LYS A O   1 
ATOM   1270 C CB  . LYS A 1 176 ? -28.53800 -16.62100 7.09900   1.000 47.20763  ? 176 LYS A CB  1 
ATOM   1271 C CG  . LYS A 1 176 ? -29.60700 -17.55400 7.61200   1.000 51.82025  ? 176 LYS A CG  1 
ATOM   1272 C CD  . LYS A 1 176 ? -30.53900 -16.89200 8.61500   1.000 56.01742  ? 176 LYS A CD  1 
ATOM   1273 C CE  . LYS A 1 176 ? -31.58500 -17.89900 9.09300   1.000 54.22005  ? 176 LYS A CE  1 
ATOM   1274 N NZ  . LYS A 1 176 ? -32.39000 -18.42000 7.93500   1.000 55.18508  ? 176 LYS A NZ  1 
ATOM   1275 N N   . ARG A 1 177 ? -25.63000 -18.04000 7.31400   1.000 50.50431  ? 177 ARG A N   1 
ATOM   1276 C CA  . ARG A 1 177 ? -24.85800 -19.00100 8.08200   1.000 53.23442  ? 177 ARG A CA  1 
ATOM   1277 C C   . ARG A 1 177 ? -25.61000 -19.38400 9.34700   1.000 56.58644  ? 177 ARG A C   1 
ATOM   1278 O O   . ARG A 1 177 ? -26.37900 -18.59400 9.90200   1.000 60.37457  ? 177 ARG A O   1 
ATOM   1279 C CB  . ARG A 1 177 ? -23.47800 -18.43700 8.42800   1.000 58.10323  ? 177 ARG A CB  1 
ATOM   1280 C CG  . ARG A 1 177 ? -23.42900 -17.49600 9.59300   1.000 55.02103  ? 177 ARG A CG  1 
ATOM   1281 C CD  . ARG A 1 177 ? -21.98700 -17.33800 10.01200  1.000 57.35921  ? 177 ARG A CD  1 
ATOM   1282 N NE  . ARG A 1 177 ? -21.80600 -16.22600 10.93600  1.000 68.16283  ? 177 ARG A NE  1 
ATOM   1283 C CZ  . ARG A 1 177 ? -22.13400 -16.25800 12.22100  1.000 69.91954  ? 177 ARG A CZ  1 
ATOM   1284 N NH1 . ARG A 1 177 ? -22.71000 -17.32200 12.76100  1.000 68.74604  ? 177 ARG A NH1 1 
ATOM   1285 N NH2 . ARG A 1 177 ? -21.87400 -15.19700 12.98500  1.000 69.15560  ? 177 ARG A NH2 1 
ATOM   1286 N N   . GLY A 1 178 ? -25.37000 -20.61600 9.80000   1.000 57.36777  ? 178 GLY A N   1 
ATOM   1287 C CA  . GLY A 1 178 ? -26.16300 -21.18300 10.87400  1.000 56.73077  ? 178 GLY A CA  1 
ATOM   1288 C C   . GLY A 1 178 ? -26.14000 -20.33100 12.12700  1.000 59.19293  ? 178 GLY A C   1 
ATOM   1289 O O   . GLY A 1 178 ? -25.25100 -19.49800 12.33600  1.000 56.57499  ? 178 GLY A O   1 
ATOM   1290 N N   . GLY A 1 179 ? -27.15900 -20.53900 12.96200  1.000 56.19356  ? 179 GLY A N   1 
ATOM   1291 C CA  . GLY A 1 179 ? -27.26800 -19.82400 14.21900  1.000 61.43824  ? 179 GLY A CA  1 
ATOM   1292 C C   . GLY A 1 179 ? -27.32900 -18.31700 14.06100  1.000 65.08687  ? 179 GLY A C   1 
ATOM   1293 O O   . GLY A 1 179 ? -26.61400 -17.58000 14.75100  1.000 64.44309  ? 179 GLY A O   1 
ATOM   1294 N N   . MET A 1 180 ? -28.17600 -17.84800 13.14400  1.000 64.24638  ? 180 MET A N   1 
ATOM   1295 C CA  . MET A 1 180 ? -28.36400 -16.42300 12.92500  1.000 60.24702  ? 180 MET A CA  1 
ATOM   1296 C C   . MET A 1 180 ? -29.82600 -16.13700 12.62100  1.000 56.73570  ? 180 MET A C   1 
ATOM   1297 O O   . MET A 1 180 ? -30.47400 -16.88500 11.88300  1.000 51.45283  ? 180 MET A O   1 
ATOM   1298 C CB  . MET A 1 180 ? -27.49300 -15.91000 11.78200  1.000 56.06210  ? 180 MET A CB  1 
ATOM   1299 C CG  . MET A 1 180 ? -26.70300 -14.68400 12.17400  1.000 63.64538  ? 180 MET A CG  1 
ATOM   1300 S SD  . MET A 1 180 ? -26.03400 -13.83300 10.73700  1.000 61.69875  ? 180 MET A SD  1 
ATOM   1301 C CE  . MET A 1 180 ? -27.53300 -13.21000 9.99800   1.000 53.60109  ? 180 MET A CE  1 
ATOM   1302 N N   . ASP A 1 181 ? -30.33300 -15.05100 13.20200  1.000 54.36536  ? 181 ASP A N   1 
ATOM   1303 C CA  . ASP A 1 181 ? -31.67500 -14.58700 12.89900  1.000 49.63446  ? 181 ASP A CA  1 
ATOM   1304 C C   . ASP A 1 181 ? -31.84700 -14.40700 11.39700  1.000 53.38949  ? 181 ASP A C   1 
ATOM   1305 O O   . ASP A 1 181 ? -30.89100 -14.11900 10.66700  1.000 52.10764  ? 181 ASP A O   1 
ATOM   1306 C CB  . ASP A 1 181 ? -31.95100 -13.26500 13.61500  1.000 54.79009  ? 181 ASP A CB  1 
ATOM   1307 C CG  . ASP A 1 181 ? -32.21300 -13.45000 15.10700  1.000 68.96686  ? 181 ASP A CG  1 
ATOM   1308 O OD1 . ASP A 1 181 ? -32.08900 -14.59800 15.60000  1.000 68.50697  ? 181 ASP A OD1 1 
ATOM   1309 O OD2 . ASP A 1 181 ? -32.55000 -12.44900 15.78500  1.000 67.50091  ? 181 ASP A OD2 1 
ATOM   1310 N N   . GLY A 1 182 ? -33.08300 -14.59200 10.93400  1.000 48.37007  ? 182 GLY A N   1 
ATOM   1311 C CA  . GLY A 1 182 ? -33.41600 -14.40400 9.53800   1.000 45.70960  ? 182 GLY A CA  1 
ATOM   1312 C C   . GLY A 1 182 ? -34.62700 -13.50000 9.38800   1.000 37.04115  ? 182 GLY A C   1 
ATOM   1313 O O   . GLY A 1 182 ? -35.23600 -13.07700 10.37100  1.000 43.61921  ? 182 GLY A O   1 
ATOM   1314 N N   . PHE A 1 183 ? -34.95600 -13.21000 8.12500   1.000 38.72235  ? 183 PHE A N   1 
ATOM   1315 C CA  . PHE A 1 183 ? -36.10700 -12.37100 7.79100   1.000 45.95601  ? 183 PHE A CA  1 
ATOM   1316 C C   . PHE A 1 183 ? -36.99000 -13.00600 6.72200   1.000 42.08008  ? 183 PHE A C   1 
ATOM   1317 O O   . PHE A 1 183 ? -37.81300 -12.31100 6.10900   1.000 39.42395  ? 183 PHE A O   1 
ATOM   1318 C CB  . PHE A 1 183 ? -35.66200 -10.97200 7.33500   1.000 41.09974  ? 183 PHE A CB  1 
ATOM   1319 C CG  . PHE A 1 183 ? -35.14600 -10.10900 8.45200   1.000 42.32303  ? 183 PHE A CG  1 
ATOM   1320 C CD1 . PHE A 1 183 ? -36.02800 -9.43100  9.28400   1.000 45.42599  ? 183 PHE A CD1 1 
ATOM   1321 C CD2 . PHE A 1 183 ? -33.78200 -9.98900  8.68100   1.000 44.21766  ? 183 PHE A CD2 1 
ATOM   1322 C CE1 . PHE A 1 183 ? -35.56000 -8.64100  10.32400  1.000 48.98003  ? 183 PHE A CE1 1 
ATOM   1323 C CE2 . PHE A 1 183 ? -33.30300 -9.20400  9.71900   1.000 45.73964  ? 183 PHE A CE2 1 
ATOM   1324 C CZ  . PHE A 1 183 ? -34.19500 -8.52800  10.54000  1.000 52.00784  ? 183 PHE A CZ  1 
ATOM   1325 N N   . LEU A 1 184 ? -36.83400 -14.30500 6.47900   1.000 37.41877  ? 184 LEU A N   1 
ATOM   1326 C CA  . LEU A 1 184 ? -37.63100 -14.97800 5.46500   1.000 43.34712  ? 184 LEU A CA  1 
ATOM   1327 C C   . LEU A 1 184 ? -39.10900 -14.75800 5.74000   1.000 43.89973  ? 184 LEU A C   1 
ATOM   1328 O O   . LEU A 1 184 ? -39.58000 -14.96300 6.86100   1.000 48.53982  ? 184 LEU A O   1 
ATOM   1329 C CB  . LEU A 1 184 ? -37.31500 -16.47800 5.45100   1.000 39.45256  ? 184 LEU A CB  1 
ATOM   1330 C CG  . LEU A 1 184 ? -37.85000 -17.33200 4.29500   1.000 39.65717  ? 184 LEU A CG  1 
ATOM   1331 C CD1 . LEU A 1 184 ? -37.21700 -16.95400 2.95400   1.000 37.04003  ? 184 LEU A CD1 1 
ATOM   1332 C CD2 . LEU A 1 184 ? -37.61600 -18.79600 4.59400   1.000 35.43568  ? 184 LEU A CD2 1 
ATOM   1333 N N   . GLY A 1 185 ? -39.82900 -14.29800 4.72300   1.000 41.29522  ? 185 GLY A N   1 
ATOM   1334 C CA  . GLY A 1 185 ? -41.26900 -14.20400 4.79600   1.000 44.18394  ? 185 GLY A CA  1 
ATOM   1335 C C   . GLY A 1 185 ? -41.81900 -12.87700 5.26700   1.000 45.30925  ? 185 GLY A C   1 
ATOM   1336 O O   . GLY A 1 185 ? -43.02500 -12.63700 5.10700   1.000 44.98049  ? 185 GLY A O   1 
ATOM   1337 N N   . MET A 1 186 ? -40.98400 -12.00100 5.81600   1.000 38.43456  ? 186 MET A N   1 
ATOM   1338 C CA  . MET A 1 186 ? -41.47600 -10.76300 6.40000   1.000 44.53122  ? 186 MET A CA  1 
ATOM   1339 C C   . MET A 1 186 ? -41.61700 -9.66700  5.34900   1.000 39.69350  ? 186 MET A C   1 
ATOM   1340 O O   . MET A 1 186 ? -41.04700 -9.74000  4.25800   1.000 44.29719  ? 186 MET A O   1 
ATOM   1341 C CB  . MET A 1 186 ? -40.54100 -10.31700 7.51100   1.000 43.13804  ? 186 MET A CB  1 
ATOM   1342 C CG  . MET A 1 186 ? -40.04000 -11.49200 8.30900   1.000 45.32263  ? 186 MET A CG  1 
ATOM   1343 S SD  . MET A 1 186 ? -39.58800 -11.02800 9.98500   1.000 47.39032  ? 186 MET A SD  1 
ATOM   1344 C CE  . MET A 1 186 ? -40.97900 -9.97000  10.39600  1.000 43.54515  ? 186 MET A CE  1 
ATOM   1345 N N   . HIS A 1 187 ? -42.39200 -8.63600  5.69200   1.000 38.14070  ? 187 HIS A N   1 
ATOM   1346 C CA  . HIS A 1 187 ? -42.61700 -7.50200  4.80500   1.000 36.46882  ? 187 HIS A CA  1 
ATOM   1347 C C   . HIS A 1 187 ? -42.04500 -6.22600  5.40500   1.000 35.95124  ? 187 HIS A C   1 
ATOM   1348 O O   . HIS A 1 187 ? -41.94300 -6.08000  6.62700   1.000 33.03373  ? 187 HIS A O   1 
ATOM   1349 C CB  . HIS A 1 187 ? -44.10000 -7.30400  4.51500   1.000 39.92871  ? 187 HIS A CB  1 
ATOM   1350 C CG  . HIS A 1 187 ? -44.71800 -8.45900  3.79900   1.000 47.18097  ? 187 HIS A CG  1 
ATOM   1351 N ND1 . HIS A 1 187 ? -45.48000 -8.30900  2.66000   1.000 43.08819  ? 187 HIS A ND1 1 
ATOM   1352 C CD2 . HIS A 1 187 ? -44.66000 -9.79200  4.04500   1.000 42.53286  ? 187 HIS A CD2 1 
ATOM   1353 C CE1 . HIS A 1 187 ? -45.87000 -9.50000  2.23700   1.000 40.27271  ? 187 HIS A CE1 1 
ATOM   1354 N NE2 . HIS A 1 187 ? -45.39000 -10.41500 3.06200   1.000 45.47376  ? 187 HIS A NE2 1 
ATOM   1355 N N   . PHE A 1 188 ? -41.66400 -5.29800  4.53000   1.000 32.90512  ? 188 PHE A N   1 
ATOM   1356 C CA  . PHE A 1 188 ? -41.06500 -4.07600  5.03100   1.000 34.45333  ? 188 PHE A CA  1 
ATOM   1357 C C   . PHE A 1 188 ? -41.70800 -2.87000  4.36400   1.000 36.37764  ? 188 PHE A C   1 
ATOM   1358 O O   . PHE A 1 188 ? -41.94500 -2.88100  3.14800   1.000 35.45847  ? 188 PHE A O   1 
ATOM   1359 C CB  . PHE A 1 188 ? -39.55600 -4.04500  4.78400   1.000 35.46261  ? 188 PHE A CB  1 
ATOM   1360 C CG  . PHE A 1 188 ? -38.77000 -5.03700  5.59300   1.000 32.61715  ? 188 PHE A CG  1 
ATOM   1361 C CD1 . PHE A 1 188 ? -38.85500 -6.40600  5.33700   1.000 39.32867  ? 188 PHE A CD1 1 
ATOM   1362 C CD2 . PHE A 1 188 ? -37.88200 -4.59900  6.55700   1.000 35.82290  ? 188 PHE A CD2 1 
ATOM   1363 C CE1 . PHE A 1 188 ? -38.09900 -7.32100  6.05600   1.000 34.95513  ? 188 PHE A CE1 1 
ATOM   1364 C CE2 . PHE A 1 188 ? -37.13000 -5.50400  7.27600   1.000 34.87190  ? 188 PHE A CE2 1 
ATOM   1365 C CZ  . PHE A 1 188 ? -37.24000 -6.87100  7.01900   1.000 38.69811  ? 188 PHE A CZ  1 
ATOM   1366 N N   . PRO A 1 189 ? -41.99300 -1.82000  5.13700   1.000 35.40230  ? 189 PRO A N   1 
ATOM   1367 C CA  . PRO A 1 189 ? -42.67600 -0.64200  4.59200   1.000 38.35775  ? 189 PRO A CA  1 
ATOM   1368 C C   . PRO A 1 189 ? -41.95900 -0.06600  3.37600   1.000 35.96369  ? 189 PRO A C   1 
ATOM   1369 O O   . PRO A 1 189 ? -40.74500 -0.19300  3.22700   1.000 33.24447  ? 189 PRO A O   1 
ATOM   1370 C CB  . PRO A 1 189 ? -42.65200 0.34500   5.76400   1.000 37.77380  ? 189 PRO A CB  1 
ATOM   1371 C CG  . PRO A 1 189 ? -42.53800 -0.51900  6.97900   1.000 36.51647  ? 189 PRO A CG  1 
ATOM   1372 C CD  . PRO A 1 189 ? -41.72700 -1.69900  6.58000   1.000 34.64243  ? 189 PRO A CD  1 
ATOM   1373 N N   . ALA A 1 190 ? -42.73500 0.59000   2.50600   1.000 40.10667  ? 190 ALA A N   1 
ATOM   1374 C CA  . ALA A 1 190 ? -42.16300 1.23900   1.33000   1.000 39.33352  ? 190 ALA A CA  1 
ATOM   1375 C C   . ALA A 1 190 ? -41.13500 2.30600   1.70900   1.000 35.73291  ? 190 ALA A C   1 
ATOM   1376 O O   . ALA A 1 190 ? -40.15500 2.51300   0.98200   1.000 35.53595  ? 190 ALA A O   1 
ATOM   1377 C CB  . ALA A 1 190 ? -43.28500 1.84200   0.48200   1.000 37.37632  ? 190 ALA A CB  1 
ATOM   1378 N N   . THR A 1 191 ? -41.32700 2.97800   2.84700   1.000 37.64057  ? 191 THR A N   1 
ATOM   1379 C CA  . THR A 1 191 ? -40.44200 4.06400   3.25200   1.000 34.72155  ? 191 THR A CA  1 
ATOM   1380 C C   . THR A 1 191 ? -39.05800 3.57300   3.64900   1.000 39.04114  ? 191 THR A C   1 
ATOM   1381 O O   . THR A 1 191 ? -38.13800 4.39300   3.78400   1.000 40.32979  ? 191 THR A O   1 
ATOM   1382 C CB  . THR A 1 191 ? -41.06800 4.85300   4.40700   1.000 36.71543  ? 191 THR A CB  1 
ATOM   1383 O OG1 . THR A 1 191 ? -41.66600 3.94900   5.35200   1.000 39.50390  ? 191 THR A OG1 1 
ATOM   1384 C CG2 . THR A 1 191 ? -42.12600 5.81000   3.88600   1.000 36.64583  ? 191 THR A CG2 1 
ATOM   1385 N N   . ASP A 1 192 ? -38.89300 2.26100   3.83900   1.000 36.70188  ? 192 ASP A N   1 
ATOM   1386 C CA  . ASP A 1 192 ? -37.59300 1.71600   4.20600   1.000 34.95004  ? 192 ASP A CA  1 
ATOM   1387 C C   . ASP A 1 192 ? -36.53100 2.02600   3.15200   1.000 34.25090  ? 192 ASP A C   1 
ATOM   1388 O O   . ASP A 1 192 ? -35.35600 2.21800   3.49400   1.000 28.39564  ? 192 ASP A O   1 
ATOM   1389 C CB  . ASP A 1 192 ? -37.73000 0.21000   4.44200   1.000 32.98046  ? 192 ASP A CB  1 
ATOM   1390 C CG  . ASP A 1 192 ? -38.06900 -0.12800  5.89000   1.000 33.93858  ? 192 ASP A CG  1 
ATOM   1391 O OD1 . ASP A 1 192 ? -38.44800 0.79100   6.65700   1.000 35.95986  ? 192 ASP A OD1 1 
ATOM   1392 O OD2 . ASP A 1 192 ? -37.93600 -1.31400  6.26200   1.000 33.24643  ? 192 ASP A OD2 1 
ATOM   1393 N N   . ILE A 1 193 ? -36.92000 2.08200   1.88300   1.000 31.04995  ? 193 ILE A N   1 
ATOM   1394 C CA  . ILE A 1 193 ? -36.05600 2.50500   0.78800   1.000 32.16740  ? 193 ILE A CA  1 
ATOM   1395 C C   . ILE A 1 193 ? -36.75100 3.64500   0.05200   1.000 37.21167  ? 193 ILE A C   1 
ATOM   1396 O O   . ILE A 1 193 ? -37.62500 3.41200   -0.79000  1.000 33.88829  ? 193 ILE A O   1 
ATOM   1397 C CB  . ILE A 1 193 ? -35.73700 1.34700   -0.17300  1.000 30.12077  ? 193 ILE A CB  1 
ATOM   1398 C CG1 . ILE A 1 193 ? -35.44600 0.04000   0.57900   1.000 31.36851  ? 193 ILE A CG1 1 
ATOM   1399 C CG2 . ILE A 1 193 ? -34.56500 1.72200   -1.04900  1.000 29.92544  ? 193 ILE A CG2 1 
ATOM   1400 C CD1 . ILE A 1 193 ? -35.20700 -1.13500  -0.36100  1.000 32.56067  ? 193 ILE A CD1 1 
ATOM   1401 N N   . PRO A 1 194 ? -36.41200 4.89500   0.35600   1.000 33.59680  ? 194 PRO A N   1 
ATOM   1402 C CA  . PRO A 1 194 ? -37.21400 6.01700   -0.13800  1.000 35.72897  ? 194 PRO A CA  1 
ATOM   1403 C C   . PRO A 1 194 ? -36.95200 6.27300   -1.61700  1.000 40.75309  ? 194 PRO A C   1 
ATOM   1404 O O   . PRO A 1 194 ? -36.09200 5.64800   -2.24600  1.000 41.31611  ? 194 PRO A O   1 
ATOM   1405 C CB  . PRO A 1 194 ? -36.78600 7.18800   0.75000   1.000 35.45700  ? 194 PRO A CB  1 
ATOM   1406 C CG  . PRO A 1 194 ? -35.46300 6.81500   1.28500   1.000 37.74216  ? 194 PRO A CG  1 
ATOM   1407 C CD  . PRO A 1 194 ? -35.43000 5.31100   1.36800   1.000 34.17902  ? 194 PRO A CD  1 
ATOM   1408 N N   . VAL A 1 195 ? -37.71700 7.22700   -2.16700  1.000 40.49582  ? 195 VAL A N   1 
ATOM   1409 C CA  . VAL A 1 195 ? -37.91800 7.28800   -3.61600  1.000 34.40562  ? 195 VAL A CA  1 
ATOM   1410 C C   . VAL A 1 195 ? -36.62900 7.66100   -4.33900  1.000 37.56273  ? 195 VAL A C   1 
ATOM   1411 O O   . VAL A 1 195 ? -36.34000 7.14100   -5.42500  1.000 35.00246  ? 195 VAL A O   1 
ATOM   1412 C CB  . VAL A 1 195 ? -39.05500 8.27200   -3.95500  1.000 40.74123  ? 195 VAL A CB  1 
ATOM   1413 C CG1 . VAL A 1 195 ? -39.33800 8.25100   -5.43500  1.000 34.95250  ? 195 VAL A CG1 1 
ATOM   1414 C CG2 . VAL A 1 195 ? -40.31200 7.92700   -3.15600  1.000 47.95848  ? 195 VAL A CG2 1 
ATOM   1415 N N   . GLN A 1 196 ? -35.84500 8.59000   -3.77700  1.000 31.41100  ? 196 GLN A N   1 
ATOM   1416 C CA  . GLN A 1 196 ? -34.62300 8.97900   -4.47200  1.000 36.19051  ? 196 GLN A CA  1 
ATOM   1417 C C   . GLN A 1 196 ? -33.58400 7.86200   -4.43500  1.000 34.35296  ? 196 GLN A C   1 
ATOM   1418 O O   . GLN A 1 196 ? -32.75600 7.77000   -5.34600  1.000 32.11689  ? 196 GLN A O   1 
ATOM   1419 C CB  . GLN A 1 196 ? -34.04300 10.27400  -3.88800  1.000 31.32246  ? 196 GLN A CB  1 
ATOM   1420 C CG  . GLN A 1 196 ? -33.26800 10.13000  -2.57000  1.000 30.83903  ? 196 GLN A CG  1 
ATOM   1421 C CD  . GLN A 1 196 ? -34.16900 10.00700  -1.35100  1.000 35.38168  ? 196 GLN A CD  1 
ATOM   1422 O OE1 . GLN A 1 196 ? -35.11900 9.23200   -1.35500  1.000 39.07101  ? 196 GLN A OE1 1 
ATOM   1423 N NE2 . GLN A 1 196 ? -33.87000 10.77200  -0.29800  1.000 35.88620  ? 196 GLN A NE2 1 
ATOM   1424 N N   . ALA A 1 197 ? -33.63900 6.98800   -3.43100  1.000 28.53259  ? 197 ALA A N   1 
ATOM   1425 C CA  . ALA A 1 197 ? -32.74100 5.83900   -3.42100  1.000 31.72551  ? 197 ALA A CA  1 
ATOM   1426 C C   . ALA A 1 197 ? -33.13200 4.83100   -4.49800  1.000 31.56359  ? 197 ALA A C   1 
ATOM   1427 O O   . ALA A 1 197 ? -32.28200 4.34600   -5.25300  1.000 25.65444  ? 197 ALA A O   1 
ATOM   1428 C CB  . ALA A 1 197 ? -32.74400 5.19700   -2.03400  1.000 29.38896  ? 197 ALA A CB  1 
ATOM   1429 N N   . ARG A 1 198 ? -34.42800 4.50700   -4.59800  1.000 38.14700  ? 198 ARG A N   1 
ATOM   1430 C CA  . ARG A 1 198 ? -34.84700 3.56800   -5.63400  1.000 29.78637  ? 198 ARG A CA  1 
ATOM   1431 C C   . ARG A 1 198 ? -34.43900 4.07800   -7.01100  1.000 32.66443  ? 198 ARG A C   1 
ATOM   1432 O O   . ARG A 1 198 ? -33.90500 3.31800   -7.83100  1.000 34.72774  ? 198 ARG A O   1 
ATOM   1433 C CB  . ARG A 1 198 ? -36.35400 3.31400   -5.53300  1.000 39.24919  ? 198 ARG A CB  1 
ATOM   1434 C CG  . ARG A 1 198 ? -36.78100 2.79300   -4.13700  1.000 35.68196  ? 198 ARG A CG  1 
ATOM   1435 C CD  . ARG A 1 198 ? -38.18300 2.15400   -4.08200  1.000 36.19712  ? 198 ARG A CD  1 
ATOM   1436 N NE  . ARG A 1 198 ? -39.28000 3.04500   -4.46500  1.000 43.04995  ? 198 ARG A NE  1 
ATOM   1437 C CZ  . ARG A 1 198 ? -39.99600 3.79900   -3.63600  1.000 37.69717  ? 198 ARG A CZ  1 
ATOM   1438 N NH1 . ARG A 1 198 ? -39.76100 3.83000   -2.33400  1.000 37.25849  ? 198 ARG A NH1 1 
ATOM   1439 N NH2 . ARG A 1 198 ? -40.97300 4.55300   -4.12900  1.000 41.40881  ? 198 ARG A NH2 1 
ATOM   1440 N N   . ALA A 1 199 ? -34.61900 5.38100   -7.25700  1.000 31.71093  ? 199 ALA A N   1 
ATOM   1441 C CA  . ALA A 1 199 ? -34.16400 5.98500   -8.50500  1.000 25.78247  ? 199 ALA A CA  1 
ATOM   1442 C C   . ALA A 1 199 ? -32.65800 5.81500   -8.68500  1.000 34.25432  ? 199 ALA A C   1 
ATOM   1443 O O   . ALA A 1 199 ? -32.19800 5.32300   -9.72400  1.000 35.58327  ? 199 ALA A O   1 
ATOM   1444 C CB  . ALA A 1 199 ? -34.53300 7.46500   -8.51600  1.000 26.78316  ? 199 ALA A CB  1 
ATOM   1445 N N   . LEU A 1 200 ? -31.86800 6.22400   -7.68300  1.000 33.20830  ? 200 LEU A N   1 
ATOM   1446 C CA  . LEU A 1 200 ? -30.41600 6.06500   -7.78200  1.000 33.29741  ? 200 LEU A CA  1 
ATOM   1447 C C   . LEU A 1 200 ? -30.03400 4.60600   -7.96900  1.000 30.83819  ? 200 LEU A C   1 
ATOM   1448 O O   . LEU A 1 200 ? -29.17700 4.29100   -8.79800  1.000 35.77034  ? 200 LEU A O   1 
ATOM   1449 C CB  . LEU A 1 200 ? -29.71600 6.63200   -6.54500  1.000 30.16954  ? 200 LEU A CB  1 
ATOM   1450 C CG  . LEU A 1 200 ? -28.19300 6.37700   -6.49600  1.000 32.34104  ? 200 LEU A CG  1 
ATOM   1451 C CD1 . LEU A 1 200 ? -27.54700 6.95300   -7.71100  1.000 30.72351  ? 200 LEU A CD1 1 
ATOM   1452 C CD2 . LEU A 1 200 ? -27.52200 6.94600   -5.23900  1.000 25.65692  ? 200 LEU A CD2 1 
ATOM   1453 N N   . TYR A 1 201 ? -30.66300 3.69600   -7.21600  1.000 32.09989  ? 201 TYR A N   1 
ATOM   1454 C CA  . TYR A 1 201 ? -30.32800 2.27300   -7.30500  1.000 32.11448  ? 201 TYR A CA  1 
ATOM   1455 C C   . TYR A 1 201 ? -30.77400 1.63300   -8.61300  1.000 36.09947  ? 201 TYR A C   1 
ATOM   1456 O O   . TYR A 1 201 ? -30.36100 0.50300   -8.91800  1.000 36.09763  ? 201 TYR A O   1 
ATOM   1457 C CB  . TYR A 1 201 ? -30.95900 1.49800   -6.15200  1.000 31.21344  ? 201 TYR A CB  1 
ATOM   1458 C CG  . TYR A 1 201 ? -30.48200 1.91000   -4.79300  1.000 34.57273  ? 201 TYR A CG  1 
ATOM   1459 C CD1 . TYR A 1 201 ? -29.34000 2.67200   -4.64000  1.000 32.87085  ? 201 TYR A CD1 1 
ATOM   1460 C CD2 . TYR A 1 201 ? -31.16500 1.51300   -3.65700  1.000 34.90487  ? 201 TYR A CD2 1 
ATOM   1461 C CE1 . TYR A 1 201 ? -28.89200 3.03400   -3.39500  1.000 34.16650  ? 201 TYR A CE1 1 
ATOM   1462 C CE2 . TYR A 1 201 ? -30.72500 1.86100   -2.40500  1.000 33.97670  ? 201 TYR A CE2 1 
ATOM   1463 C CZ  . TYR A 1 201 ? -29.58800 2.63100   -2.27800  1.000 34.19583  ? 201 TYR A CZ  1 
ATOM   1464 O OH  . TYR A 1 201 ? -29.14900 3.00500   -1.03000  1.000 27.56343  ? 201 TYR A OH  1 
ATOM   1465 N N   . THR A 1 202 ? -31.63600 2.30000   -9.37200  1.000 32.28124  ? 202 THR A N   1 
ATOM   1466 C CA  . THR A 1 202 ? -31.93200 1.83000   -10.71700 1.000 32.41356  ? 202 THR A CA  1 
ATOM   1467 C C   . THR A 1 202 ? -30.74300 2.03400   -11.64100 1.000 37.02613  ? 202 THR A C   1 
ATOM   1468 O O   . THR A 1 202 ? -30.35800 1.12200   -12.38000 1.000 35.32715  ? 202 THR A O   1 
ATOM   1469 C CB  . THR A 1 202 ? -33.15500 2.55500   -11.25900 1.000 33.21409  ? 202 THR A CB  1 
ATOM   1470 O OG1 . THR A 1 202 ? -34.24800 2.32600   -10.36400 1.000 31.49213  ? 202 THR A OG1 1 
ATOM   1471 C CG2 . THR A 1 202 ? -33.49600 2.01600   -12.60500 1.000 28.42799  ? 202 THR A CG2 1 
ATOM   1472 N N   . ARG A 1 203 ? -30.14300 3.22600   -11.61500 1.000 35.05868  ? 203 ARG A N   1 
ATOM   1473 C CA  . ARG A 1 203 ? -29.04400 3.51600   -12.52400 1.000 43.10415  ? 203 ARG A CA  1 
ATOM   1474 C C   . ARG A 1 203 ? -27.67900 3.19700   -11.92900 1.000 38.72583  ? 203 ARG A C   1 
ATOM   1475 O O   . ARG A 1 203 ? -26.67000 3.28500   -12.63600 1.000 43.92417  ? 203 ARG A O   1 
ATOM   1476 C CB  . ARG A 1 203 ? -29.09900 4.98400   -12.97900 1.000 46.80500  ? 203 ARG A CB  1 
ATOM   1477 C CG  . ARG A 1 203 ? -28.73800 6.00600   -11.92900 1.000 48.38853  ? 203 ARG A CG  1 
ATOM   1478 C CD  . ARG A 1 203 ? -29.10400 7.40300   -12.43000 1.000 58.57247  ? 203 ARG A CD  1 
ATOM   1479 N NE  . ARG A 1 203 ? -28.27000 8.47600   -11.88700 1.000 68.34411  ? 203 ARG A NE  1 
ATOM   1480 C CZ  . ARG A 1 203 ? -27.05100 8.78200   -12.32400 1.000 66.98979  ? 203 ARG A CZ  1 
ATOM   1481 N NH1 . ARG A 1 203 ? -26.43600 8.04400   -13.23800 1.000 67.13587  ? 203 ARG A NH1 1 
ATOM   1482 N NH2 . ARG A 1 203 ? -26.43400 9.85800   -11.83300 1.000 60.28751  ? 203 ARG A NH2 1 
ATOM   1483 N N   . ASN A 1 204 ? -27.61900 2.80400   -10.66300 1.000 40.41685  ? 204 ASN A N   1 
ATOM   1484 C CA  . ASN A 1 204 ? -26.36100 2.44400   -10.01400 1.000 31.97678  ? 204 ASN A CA  1 
ATOM   1485 C C   . ASN A 1 204 ? -26.56800 1.13800   -9.26600  1.000 32.61632  ? 204 ASN A C   1 
ATOM   1486 O O   . ASN A 1 204 ? -27.09100 1.14900   -8.13900  1.000 37.06711  ? 204 ASN A O   1 
ATOM   1487 C CB  . ASN A 1 204 ? -25.91000 3.54200   -9.06900  1.000 40.33672  ? 204 ASN A CB  1 
ATOM   1488 C CG  . ASN A 1 204 ? -24.50100 3.33900   -8.60000  1.000 36.23535  ? 204 ASN A CG  1 
ATOM   1489 O OD1 . ASN A 1 204 ? -23.96800 2.23100   -8.68200  1.000 36.64056  ? 204 ASN A OD1 1 
ATOM   1490 N ND2 . ASN A 1 204 ? -23.87700 4.40200   -8.12400  1.000 36.44558  ? 204 ASN A ND2 1 
ATOM   1491 N N   . PRO A 1 205 ? -26.15200 0.00200   -9.83600  1.000 33.42630  ? 205 PRO A N   1 
ATOM   1492 C CA  . PRO A 1 205 ? -26.66100 -1.29700  -9.36100  1.000 32.32068  ? 205 PRO A CA  1 
ATOM   1493 C C   . PRO A 1 205 ? -25.99600 -1.88500  -8.11100  1.000 35.68221  ? 205 PRO A C   1 
ATOM   1494 O O   . PRO A 1 205 ? -26.52800 -2.87200  -7.58600  1.000 31.64841  ? 205 PRO A O   1 
ATOM   1495 C CB  . PRO A 1 205 ? -26.45300 -2.22100  -10.57600 1.000 32.55485  ? 205 PRO A CB  1 
ATOM   1496 C CG  . PRO A 1 205 ? -25.41400 -1.56300  -11.41500 1.000 35.04595  ? 205 PRO A CG  1 
ATOM   1497 C CD  . PRO A 1 205 ? -25.46400 -0.08600  -11.13800 1.000 33.85395  ? 205 PRO A CD  1 
ATOM   1498 N N   . LEU A 1 206 ? -24.88000 -1.33500  -7.61200  1.000 38.80384  ? 206 LEU A N   1 
ATOM   1499 C CA  . LEU A 1 206 ? -24.16000 -1.86900  -6.45700  1.000 30.73814  ? 206 LEU A CA  1 
ATOM   1500 C C   . LEU A 1 206 ? -24.05700 -0.81000  -5.37800  1.000 27.77499  ? 206 LEU A C   1 
ATOM   1501 O O   . LEU A 1 206 ? -23.96300 0.38200   -5.67600  1.000 37.96192  ? 206 LEU A O   1 
ATOM   1502 C CB  . LEU A 1 206 ? -22.72600 -2.29900  -6.80200  1.000 27.24843  ? 206 LEU A CB  1 
ATOM   1503 C CG  . LEU A 1 206 ? -22.38900 -3.59400  -7.53100  1.000 30.97192  ? 206 LEU A CG  1 
ATOM   1504 C CD1 . LEU A 1 206 ? -23.65200 -4.36800  -7.90000  1.000 41.43950  ? 206 LEU A CD1 1 
ATOM   1505 C CD2 . LEU A 1 206 ? -21.53500 -3.31800  -8.77900  1.000 37.22914  ? 206 LEU A CD2 1 
ATOM   1506 N N   . ARG A 1 207 ? -24.03900 -1.24800  -4.12200  1.000 30.74202  ? 207 ARG A N   1 
ATOM   1507 C CA  . ARG A 1 207 ? -23.60200 -0.38900  -3.02000  1.000 33.35910  ? 207 ARG A CA  1 
ATOM   1508 C C   . ARG A 1 207 ? -22.97600 -1.26200  -1.94400  1.000 31.12599  ? 207 ARG A C   1 
ATOM   1509 O O   . ARG A 1 207 ? -23.55300 -2.28600  -1.56300  1.000 28.80954  ? 207 ARG A O   1 
ATOM   1510 C CB  . ARG A 1 207 ? -24.76300 0.43500   -2.43000  1.000 31.13587  ? 207 ARG A CB  1 
ATOM   1511 C CG  . ARG A 1 207 ? -25.92000 -0.39500  -1.94000  1.000 32.79015  ? 207 ARG A CG  1 
ATOM   1512 C CD  . ARG A 1 207 ? -27.25200 0.07000   -2.51000  1.000 31.10756  ? 207 ARG A CD  1 
ATOM   1513 N NE  . ARG A 1 207 ? -27.26100 0.11900   -3.96900  1.000 34.96275  ? 207 ARG A NE  1 
ATOM   1514 C CZ  . ARG A 1 207 ? -27.98700 -0.66800  -4.75900  1.000 35.23119  ? 207 ARG A CZ  1 
ATOM   1515 N NH1 . ARG A 1 207 ? -28.76500 -1.62300  -4.26700  1.000 25.83629  ? 207 ARG A NH1 1 
ATOM   1516 N NH2 . ARG A 1 207 ? -27.91800 -0.50100  -6.08000  1.000 35.29876  ? 207 ARG A NH2 1 
ATOM   1517 N N   . LEU A 1 208 ? -21.80100 -0.86200  -1.45700  1.000 32.89098  ? 208 LEU A N   1 
ATOM   1518 C CA  . LEU A 1 208 ? -21.17900 -1.51000  -0.30400  1.000 31.62126  ? 208 LEU A CA  1 
ATOM   1519 C C   . LEU A 1 208 ? -21.10100 -0.50700  0.83800   1.000 30.86560  ? 208 LEU A C   1 
ATOM   1520 O O   . LEU A 1 208 ? -20.53600 0.58200   0.67600   1.000 30.34802  ? 208 LEU A O   1 
ATOM   1521 C CB  . LEU A 1 208 ? -19.78800 -2.05700  -0.64000  1.000 25.41342  ? 208 LEU A CB  1 
ATOM   1522 C CG  . LEU A 1 208 ? -18.92600 -2.57400  0.53200   1.000 34.67670  ? 208 LEU A CG  1 
ATOM   1523 C CD1 . LEU A 1 208 ? -19.40700 -3.93400  1.12100   1.000 29.49042  ? 208 LEU A CD1 1 
ATOM   1524 C CD2 . LEU A 1 208 ? -17.44000 -2.64300  0.14000   1.000 34.93694  ? 208 LEU A CD2 1 
ATOM   1525 N N   . ILE A 1 209 ? -21.68600 -0.85700  1.97800   1.000 30.73009  ? 209 ILE A N   1 
ATOM   1526 C CA  . ILE A 1 209 ? -21.42700 -0.15300  3.23000   1.000 31.41827  ? 209 ILE A CA  1 
ATOM   1527 C C   . ILE A 1 209 ? -20.51300 -1.05500  4.04200   1.000 27.48739  ? 209 ILE A C   1 
ATOM   1528 O O   . ILE A 1 209 ? -20.95300 -2.07300  4.58200   1.000 31.63173  ? 209 ILE A O   1 
ATOM   1529 C CB  . ILE A 1 209 ? -22.71500 0.16400   3.99900   1.000 31.35849  ? 209 ILE A CB  1 
ATOM   1530 C CG1 . ILE A 1 209 ? -23.67000 1.02800   3.15900   1.000 27.76458  ? 209 ILE A CG1 1 
ATOM   1531 C CG2 . ILE A 1 209 ? -22.36900 0.81300   5.31100   1.000 29.25779  ? 209 ILE A CG2 1 
ATOM   1532 C CD1 . ILE A 1 209 ? -24.77600 0.22800   2.47800   1.000 27.95924  ? 209 ILE A CD1 1 
ATOM   1533 N N   . ALA A 1 210 ? -19.23700 -0.70400  4.12700   1.000 31.69897  ? 210 ALA A N   1 
ATOM   1534 C CA  . ALA A 1 210 ? -18.27600 -1.64500  4.69300   1.000 31.57835  ? 210 ALA A CA  1 
ATOM   1535 C C   . ALA A 1 210 ? -18.22700 -1.59300  6.22200   1.000 35.57714  ? 210 ALA A C   1 
ATOM   1536 O O   . ALA A 1 210 ? -17.89700 -2.60700  6.85100   1.000 33.20690  ? 210 ALA A O   1 
ATOM   1537 C CB  . ALA A 1 210 ? -16.88700 -1.39200  4.09600   1.000 29.83260  ? 210 ALA A CB  1 
ATOM   1538 N N   . ASP A 1 211 ? -18.55500 -0.44900  6.84400   1.000 31.30692  ? 211 ASP A N   1 
ATOM   1539 C CA  . ASP A 1 211 ? -18.47100 -0.33800  8.30300   1.000 38.26265  ? 211 ASP A CA  1 
ATOM   1540 C C   . ASP A 1 211 ? -19.56300 0.62200   8.77800   1.000 40.38457  ? 211 ASP A C   1 
ATOM   1541 O O   . ASP A 1 211 ? -19.37100 1.84300   8.74600   1.000 41.33704  ? 211 ASP A O   1 
ATOM   1542 C CB  . ASP A 1 211 ? -17.08200 0.12500   8.73000   1.000 36.34267  ? 211 ASP A CB  1 
ATOM   1543 C CG  . ASP A 1 211 ? -16.88200 0.09900   10.23700  1.000 40.74350  ? 211 ASP A CG  1 
ATOM   1544 O OD1 . ASP A 1 211 ? -17.84800 0.31400   11.00500  1.000 38.28019  ? 211 ASP A OD1 1 
ATOM   1545 O OD2 . ASP A 1 211 ? -15.73000 -0.13200  10.66500  1.000 48.12202  ? 211 ASP A OD2 1 
ATOM   1546 N N   . ALA A 1 212 ? -20.68400 0.06000   9.26200   1.000 39.18273  ? 212 ALA A N   1 
ATOM   1547 C CA  . ALA A 1 212 ? -21.85100 0.85300   9.65700   1.000 41.14860  ? 212 ALA A CA  1 
ATOM   1548 C C   . ALA A 1 212 ? -21.59700 1.72300   10.87600  1.000 43.98503  ? 212 ALA A C   1 
ATOM   1549 O O   . ALA A 1 212 ? -22.41900 2.60500   11.16300  1.000 43.02111  ? 212 ALA A O   1 
ATOM   1550 C CB  . ALA A 1 212 ? -23.05400 -0.05200  9.94100   1.000 34.51982  ? 212 ALA A CB  1 
ATOM   1551 N N   . ARG A 1 213 ? -20.50100 1.48300   11.60400  1.000 43.89634  ? 213 ARG A N   1 
ATOM   1552 C CA  . ARG A 1 213 ? -20.13000 2.29200   12.75800  1.000 45.71893  ? 213 ARG A CA  1 
ATOM   1553 C C   . ARG A 1 213 ? -19.19600 3.43100   12.39700  1.000 40.25456  ? 213 ARG A C   1 
ATOM   1554 O O   . ARG A 1 213 ? -19.01600 4.34500   13.20800  1.000 38.95787  ? 213 ARG A O   1 
ATOM   1555 C CB  . ARG A 1 213 ? -19.45000 1.41700   13.81700  1.000 47.97467  ? 213 ARG A CB  1 
ATOM   1556 C CG  . ARG A 1 213 ? -20.35600 0.37300   14.40800  1.000 53.66898  ? 213 ARG A CG  1 
ATOM   1557 C CD  . ARG A 1 213 ? -21.19500 0.99700   15.49500  1.000 57.94337  ? 213 ARG A CD  1 
ATOM   1558 N NE  . ARG A 1 213 ? -22.19700 0.08700   16.03000  1.000 58.23733  ? 213 ARG A NE  1 
ATOM   1559 C CZ  . ARG A 1 213 ? -22.98200 0.38100   17.05800  1.000 68.29989  ? 213 ARG A CZ  1 
ATOM   1560 N NH1 . ARG A 1 213 ? -22.85800 1.52900   17.71400  1.000 66.17079  ? 213 ARG A NH1 1 
ATOM   1561 N NH2 . ARG A 1 213 ? -23.91700 -0.49300  17.43400  1.000 62.02869  ? 213 ARG A NH2 1 
ATOM   1562 N N   . ALA A 1 214 ? -18.59700 3.38500   11.20900  1.000 40.68393  ? 214 ALA A N   1 
ATOM   1563 C CA  . ALA A 1 214 ? -17.57500 4.35100   10.82600  1.000 37.94520  ? 214 ALA A CA  1 
ATOM   1564 C C   . ALA A 1 214 ? -18.19500 5.71200   10.54200  1.000 40.67126  ? 214 ALA A C   1 
ATOM   1565 O O   . ALA A 1 214 ? -19.31000 5.80400   10.02300  1.000 43.13629  ? 214 ALA A O   1 
ATOM   1566 C CB  . ALA A 1 214 ? -16.82400 3.84900   9.59100   1.000 31.68901  ? 214 ALA A CB  1 
ATOM   1567 N N   . ARG A 1 215 ? -17.46400 6.78100   10.89000  1.000 44.22826  ? 215 ARG A N   1 
ATOM   1568 C CA  . ARG A 1 215 ? -17.86700 8.11500   10.46000  1.000 40.21346  ? 215 ARG A CA  1 
ATOM   1569 C C   . ARG A 1 215 ? -17.37300 8.38000   9.04100   1.000 35.05945  ? 215 ARG A C   1 
ATOM   1570 O O   . ARG A 1 215 ? -16.34500 7.84100   8.62400   1.000 33.12144  ? 215 ARG A O   1 
ATOM   1571 C CB  . ARG A 1 215 ? -17.31200 9.18600   11.39800  1.000 45.40606  ? 215 ARG A CB  1 
ATOM   1572 C CG  . ARG A 1 215 ? -18.34700 9.75800   12.36400  1.000 50.15731  ? 215 ARG A CG  1 
ATOM   1573 C CD  . ARG A 1 215 ? -18.70300 8.74000   13.44400  1.000 58.62736  ? 215 ARG A CD  1 
ATOM   1574 N NE  . ARG A 1 215 ? -17.51900 8.30000   14.17700  1.000 70.64701  ? 215 ARG A NE  1 
ATOM   1575 C CZ  . ARG A 1 215 ? -17.50200 7.30600   15.05800  1.000 74.62747  ? 215 ARG A CZ  1 
ATOM   1576 N NH1 . ARG A 1 215 ? -18.59300 6.60700   15.33700  1.000 69.27325  ? 215 ARG A NH1 1 
ATOM   1577 N NH2 . ARG A 1 215 ? -16.36000 7.00300   15.67300  1.000 82.36611  ? 215 ARG A NH2 1 
ATOM   1578 N N   . PRO A 1 216 ? -18.08300 9.20000   8.27400   1.000 36.78845  ? 216 PRO A N   1 
ATOM   1579 C CA  . PRO A 1 216 ? -17.63100 9.48500   6.90400   1.000 32.92368  ? 216 PRO A CA  1 
ATOM   1580 C C   . PRO A 1 216 ? -16.36800 10.33000  6.90500   1.000 32.12566  ? 216 PRO A C   1 
ATOM   1581 O O   . PRO A 1 216 ? -16.00200 10.96800  7.89500   1.000 32.92478  ? 216 PRO A O   1 
ATOM   1582 C CB  . PRO A 1 216 ? -18.81000 10.23400  6.26600   1.000 27.77932  ? 216 PRO A CB  1 
ATOM   1583 C CG  . PRO A 1 216 ? -19.67400 10.68100  7.39800   1.000 26.74603  ? 216 PRO A CG  1 
ATOM   1584 C CD  . PRO A 1 216 ? -19.40300 9.78200   8.58500   1.000 33.74663  ? 216 PRO A CD  1 
ATOM   1585 N N   . VAL A 1 217 ? -15.67800 10.30700  5.77200   1.000 30.07988  ? 217 VAL A N   1 
ATOM   1586 C CA  . VAL A 1 217 ? -14.54000 11.18500  5.51900   1.000 25.26481  ? 217 VAL A CA  1 
ATOM   1587 C C   . VAL A 1 217 ? -15.02200 12.33800  4.64200   1.000 31.24196  ? 217 VAL A C   1 
ATOM   1588 O O   . VAL A 1 217 ? -15.58500 12.08300  3.56100   1.000 30.41570  ? 217 VAL A O   1 
ATOM   1589 C CB  . VAL A 1 217 ? -13.39900 10.41900  4.84700   1.000 26.52707  ? 217 VAL A CB  1 
ATOM   1590 C CG1 . VAL A 1 217 ? -12.22400 11.33100  4.60300   1.000 26.02147  ? 217 VAL A CG1 1 
ATOM   1591 C CG2 . VAL A 1 217 ? -13.03700 9.22200   5.69000   1.000 27.45790  ? 217 VAL A CG2 1 
ATOM   1592 N N   . PRO A 1 218 ? -14.85300 13.59100  5.05200   1.000 29.89823  ? 218 PRO A N   1 
ATOM   1593 C CA  . PRO A 1 218 ? -15.33100 14.70500  4.23100   1.000 27.56436  ? 218 PRO A CA  1 
ATOM   1594 C C   . PRO A 1 218 ? -14.39900 15.02200  3.07100   1.000 31.33170  ? 218 PRO A C   1 
ATOM   1595 O O   . PRO A 1 218 ? -13.19300 14.74500  3.09900   1.000 25.02267  ? 218 PRO A O   1 
ATOM   1596 C CB  . PRO A 1 218 ? -15.36400 15.87100  5.22300   1.000 26.10202  ? 218 PRO A CB  1 
ATOM   1597 C CG  . PRO A 1 218 ? -14.29300 15.54500  6.17600   1.000 27.19557  ? 218 PRO A CG  1 
ATOM   1598 C CD  . PRO A 1 218 ? -14.34200 14.05600  6.35200   1.000 26.36389  ? 218 PRO A CD  1 
ATOM   1599 N N   . LEU A 1 219 ? -14.98800 15.65900  2.05700   1.000 32.38646  ? 219 LEU A N   1 
ATOM   1600 C CA  . LEU A 1 219 ? -14.25300 16.20500  0.92200   1.000 30.45271  ? 219 LEU A CA  1 
ATOM   1601 C C   . LEU A 1 219 ? -13.84100 17.65500  1.17600   1.000 30.86560  ? 219 LEU A C   1 
ATOM   1602 O O   . LEU A 1 219 ? -14.54300 18.41500  1.85000   1.000 30.88374  ? 219 LEU A O   1 
ATOM   1603 C CB  . LEU A 1 219 ? -15.10200 16.12600  -0.35300  1.000 26.54941  ? 219 LEU A CB  1 
ATOM   1604 C CG  . LEU A 1 219 ? -15.59000 14.71100  -0.72800  1.000 28.01868  ? 219 LEU A CG  1 
ATOM   1605 C CD1 . LEU A 1 219 ? -16.60500 14.74300  -1.87500  1.000 25.96203  ? 219 LEU A CD1 1 
ATOM   1606 C CD2 . LEU A 1 219 ? -14.41900 13.78700  -1.08800  1.000 25.70495  ? 219 LEU A CD2 1 
ATOM   1607 N N   . LEU A 1 220 ? -12.69600 18.04200  0.60500   1.000 32.40798  ? 220 LEU A N   1 
ATOM   1608 C CA  . LEU A 1 220 ? -12.24200 19.42000  0.64000   1.000 27.75921  ? 220 LEU A CA  1 
ATOM   1609 C C   . LEU A 1 220 ? -12.07900 19.97400  -0.77200  1.000 33.16049  ? 220 LEU A C   1 
ATOM   1610 O O   . LEU A 1 220 ? -11.41200 19.34200  -1.60800  1.000 35.91952  ? 220 LEU A O   1 
ATOM   1611 C CB  . LEU A 1 220 ? -10.92200 19.52100  1.37000   1.000 35.46688  ? 220 LEU A CB  1 
ATOM   1612 C CG  . LEU A 1 220 ? -10.95900 18.97700  2.78300   1.000 35.73051  ? 220 LEU A CG  1 
ATOM   1613 C CD1 . LEU A 1 220 ? -9.72300  18.13200  2.92200   1.000 40.10985  ? 220 LEU A CD1 1 
ATOM   1614 C CD2 . LEU A 1 220 ? -10.95000 20.14700  3.74900   1.000 40.49526  ? 220 LEU A CD2 1 
ATOM   1615 N N   . PRO A 1 221 ? -12.65400 21.15600  -1.08100  1.000 32.46659  ? 221 PRO A N   1 
ATOM   1616 C CA  . PRO A 1 221 ? -13.54200 21.97000  -0.23400  1.000 29.90335  ? 221 PRO A CA  1 
ATOM   1617 C C   . PRO A 1 221 ? -14.85200 21.22800  0.00200   1.000 28.58044  ? 221 PRO A C   1 
ATOM   1618 O O   . PRO A 1 221 ? -15.06300 20.17800  -0.60200  1.000 24.45510  ? 221 PRO A O   1 
ATOM   1619 C CB  . PRO A 1 221 ? -13.74000 23.24800  -1.06400  1.000 31.74692  ? 221 PRO A CB  1 
ATOM   1620 C CG  . PRO A 1 221 ? -12.65200 23.23000  -2.11800  1.000 26.81313  ? 221 PRO A CG  1 
ATOM   1621 C CD  . PRO A 1 221 ? -12.41800 21.78900  -2.38900  1.000 25.29200  ? 221 PRO A CD  1 
ATOM   1622 N N   . PRO A 1 222 ? -15.74500 21.71100  0.86900   1.000 32.64217  ? 222 PRO A N   1 
ATOM   1623 C CA  . PRO A 1 222 ? -17.05300 21.04600  1.01800   1.000 29.73150  ? 222 PRO A CA  1 
ATOM   1624 C C   . PRO A 1 222 ? -17.94000 21.24000  -0.17900  1.000 30.38952  ? 222 PRO A C   1 
ATOM   1625 O O   . PRO A 1 222 ? -18.94900 20.53500  -0.29900  1.000 36.65473  ? 222 PRO A O   1 
ATOM   1626 C CB  . PRO A 1 222 ? -17.65500 21.71700  2.25700   1.000 27.44110  ? 222 PRO A CB  1 
ATOM   1627 C CG  . PRO A 1 222 ? -16.45900 22.35100  2.96200   1.000 30.01181  ? 222 PRO A CG  1 
ATOM   1628 C CD  . PRO A 1 222 ? -15.58800 22.80300  1.83100   1.000 29.78079  ? 222 PRO A CD  1 
ATOM   1629 N N   . VAL A 1 223 ? -17.61200 22.18800  -1.05500  1.000 26.03270  ? 223 VAL A N   1 
ATOM   1630 C CA  . VAL A 1 223 ? -18.35900 22.43400  -2.27700  1.000 27.66373  ? 223 VAL A CA  1 
ATOM   1631 C C   . VAL A 1 223 ? -17.38600 22.46200  -3.45000  1.000 30.34712  ? 223 VAL A C   1 
ATOM   1632 O O   . VAL A 1 223 ? -16.20100 22.79100  -3.30100  1.000 30.99154  ? 223 VAL A O   1 
ATOM   1633 C CB  . VAL A 1 223 ? -19.15600 23.75900  -2.19200  1.000 26.70613  ? 223 VAL A CB  1 
ATOM   1634 C CG1 . VAL A 1 223 ? -20.01500 23.76600  -0.97000  1.000 28.12904  ? 223 VAL A CG1 1 
ATOM   1635 C CG2 . VAL A 1 223 ? -18.22400 24.92200  -2.12500  1.000 29.95853  ? 223 VAL A CG2 1 
ATOM   1636 N N   . VAL A 1 224 ? -17.88800 22.10600  -4.62800  1.000 29.64695  ? 224 VAL A N   1 
ATOM   1637 C CA  . VAL A 1 224 ? -17.15000 22.35600  -5.86400  1.000 27.45829  ? 224 VAL A CA  1 
ATOM   1638 C C   . VAL A 1 224 ? -17.24700 23.86500  -6.07600  1.000 29.71652  ? 224 VAL A C   1 
ATOM   1639 O O   . VAL A 1 224 ? -18.36200 24.40100  -6.17800  1.000 28.87885  ? 224 VAL A O   1 
ATOM   1640 C CB  . VAL A 1 224 ? -17.71700 21.54100  -7.04100  1.000 26.85519  ? 224 VAL A CB  1 
ATOM   1641 C CG1 . VAL A 1 224 ? -16.85600 21.72600  -8.28700  1.000 27.16033  ? 224 VAL A CG1 1 
ATOM   1642 C CG2 . VAL A 1 224 ? -17.83100 20.04800  -6.68200  1.000 23.94076  ? 224 VAL A CG2 1 
ATOM   1643 N N   . PRO A 1 225 ? -16.13200 24.60200  -6.08800  1.000 31.98922  ? 225 PRO A N   1 
ATOM   1644 C CA  . PRO A 1 225 ? -16.24700 26.07200  -6.06100  1.000 34.97108  ? 225 PRO A CA  1 
ATOM   1645 C C   . PRO A 1 225 ? -17.08100 26.63100  -7.20700  1.000 33.90768  ? 225 PRO A C   1 
ATOM   1646 O O   . PRO A 1 225 ? -17.81100 27.61000  -7.01900  1.000 35.52162  ? 225 PRO A O   1 
ATOM   1647 C CB  . PRO A 1 225 ? -14.78300 26.53900  -6.12900  1.000 38.89000  ? 225 PRO A CB  1 
ATOM   1648 C CG  . PRO A 1 225 ? -13.96300 25.33600  -5.76700  1.000 33.86182  ? 225 PRO A CG  1 
ATOM   1649 C CD  . PRO A 1 225 ? -14.73800 24.15900  -6.24900  1.000 31.16321  ? 225 PRO A CD  1 
ATOM   1650 N N   . ALA A 1 226 ? -17.01100 26.02200  -8.39000  1.000 31.71687  ? 226 ALA A N   1 
ATOM   1651 C CA  . ALA A 1 226 ? -17.82900 26.49200  -9.50300  1.000 32.24669  ? 226 ALA A CA  1 
ATOM   1652 C C   . ALA A 1 226 ? -19.31600 26.36600  -9.19500  1.000 39.08588  ? 226 ALA A C   1 
ATOM   1653 O O   . ALA A 1 226 ? -20.09700 27.27900  -9.49400  1.000 38.10271  ? 226 ALA A O   1 
ATOM   1654 C CB  . ALA A 1 226 ? -17.49000 25.71600  -10.76900 1.000 31.78495  ? 226 ALA A CB  1 
ATOM   1655 N N   . LEU A 1 227 ? -19.73000 25.24700  -8.58200  1.000 37.30911  ? 227 LEU A N   1 
ATOM   1656 C CA  . LEU A 1 227 ? -21.15000 24.91700  -8.49400  1.000 36.32117  ? 227 LEU A CA  1 
ATOM   1657 C C   . LEU A 1 227 ? -21.83800 25.42200  -7.23400  1.000 32.90515  ? 227 LEU A C   1 
ATOM   1658 O O   . LEU A 1 227 ? -23.06800 25.54400  -7.22600  1.000 33.59168  ? 227 LEU A O   1 
ATOM   1659 C CB  . LEU A 1 227 ? -21.35300 23.39900  -8.56500  1.000 32.46278  ? 227 LEU A CB  1 
ATOM   1660 C CG  . LEU A 1 227 ? -20.85400 22.65000  -9.78800  1.000 28.48060  ? 227 LEU A CG  1 
ATOM   1661 C CD1 . LEU A 1 227 ? -21.50400 21.27100  -9.84600  1.000 33.45058  ? 227 LEU A CD1 1 
ATOM   1662 C CD2 . LEU A 1 227 ? -21.13700 23.43900  -11.04400 1.000 33.45015  ? 227 LEU A CD2 1 
ATOM   1663 N N   . GLY A 1 228 ? -21.10200 25.66700  -6.15800  1.000 34.03889  ? 228 GLY A N   1 
ATOM   1664 C CA  . GLY A 1 228 ? -21.75000 25.97900  -4.89800  1.000 33.63285  ? 228 GLY A CA  1 
ATOM   1665 C C   . GLY A 1 228 ? -22.50900 24.84000  -4.24500  1.000 33.54650  ? 228 GLY A C   1 
ATOM   1666 O O   . GLY A 1 228 ? -23.41300 25.09100  -3.43800  1.000 35.07808  ? 228 GLY A O   1 
ATOM   1667 N N   . ARG A 1 229 ? -22.17000 23.59400  -4.55700  1.000 34.54948  ? 229 ARG A N   1 
ATOM   1668 C CA  . ARG A 1 229 ? -22.75100 22.44200  -3.87800  1.000 30.22950  ? 229 ARG A CA  1 
ATOM   1669 C C   . ARG A 1 229 ? -21.69800 21.35200  -3.83300  1.000 30.23021  ? 229 ARG A C   1 
ATOM   1670 O O   . ARG A 1 229 ? -20.71700 21.39800  -4.58200  1.000 29.34244  ? 229 ARG A O   1 
ATOM   1671 C CB  . ARG A 1 229 ? -23.99800 21.92600  -4.59700  1.000 27.07997  ? 229 ARG A CB  1 
ATOM   1672 C CG  . ARG A 1 229 ? -23.65200 21.34800  -5.93800  1.000 27.57253  ? 229 ARG A CG  1 
ATOM   1673 C CD  . ARG A 1 229 ? -24.53400 20.20300  -6.29800  1.000 30.87292  ? 229 ARG A CD  1 
ATOM   1674 N NE  . ARG A 1 229 ? -24.47700 19.97400  -7.73700  1.000 31.07077  ? 229 ARG A NE  1 
ATOM   1675 C CZ  . ARG A 1 229 ? -23.68300 19.09600  -8.34100  1.000 35.35457  ? 229 ARG A CZ  1 
ATOM   1676 N NH1 . ARG A 1 229 ? -22.85000 18.32100  -7.65700  1.000 37.18957  ? 229 ARG A NH1 1 
ATOM   1677 N NH2 . ARG A 1 229 ? -23.73700 18.98100  -9.66500  1.000 33.83614  ? 229 ARG A NH2 1 
ATOM   1678 N N   . PRO A 1 230 ? -21.89300 20.33300  -2.99400  1.000 28.57449  ? 230 PRO A N   1 
ATOM   1679 C CA  . PRO A 1 230 ? -20.93700 19.23000  -2.94400  1.000 27.69108  ? 230 PRO A CA  1 
ATOM   1680 C C   . PRO A 1 230 ? -20.81500 18.49900  -4.27300  1.000 29.35064  ? 230 PRO A C   1 
ATOM   1681 O O   . PRO A 1 230 ? -21.69400 18.55600  -5.13700  1.000 32.57569  ? 230 PRO A O   1 
ATOM   1682 C CB  . PRO A 1 230 ? -21.51400 18.32000  -1.85900  1.000 32.22788  ? 230 PRO A CB  1 
ATOM   1683 C CG  . PRO A 1 230 ? -22.26900 19.26500  -0.95300  1.000 26.06065  ? 230 PRO A CG  1 
ATOM   1684 C CD  . PRO A 1 230 ? -22.87400 20.26400  -1.88700  1.000 30.19156  ? 230 PRO A CD  1 
ATOM   1685 N N   . LEU A 1 231 ? -19.67700 17.82100  -4.43400  1.000 28.52874  ? 231 LEU A N   1 
ATOM   1686 C CA  . LEU A 1 231 ? -19.46000 16.93200  -5.57100  1.000 29.38763  ? 231 LEU A CA  1 
ATOM   1687 C C   . LEU A 1 231 ? -20.55100 15.85600  -5.64900  1.000 27.96169  ? 231 LEU A C   1 
ATOM   1688 O O   . LEU A 1 231 ? -20.89300 15.22700  -4.64100  1.000 27.64143  ? 231 LEU A O   1 
ATOM   1689 C CB  . LEU A 1 231 ? -18.07900 16.28100  -5.44300  1.000 26.85864  ? 231 LEU A CB  1 
ATOM   1690 C CG  . LEU A 1 231 ? -17.73400 15.22900  -6.48500  1.000 32.69846  ? 231 LEU A CG  1 
ATOM   1691 C CD1 . LEU A 1 231 ? -18.00300 15.80200  -7.89900  1.000 31.00900  ? 231 LEU A CD1 1 
ATOM   1692 C CD2 . LEU A 1 231 ? -16.29000 14.79700  -6.32000  1.000 21.22152  ? 231 LEU A CD2 1 
ATOM   1693 N N   . ASP A 1 232 ? -21.10800 15.65800  -6.84900  1.000 31.89122  ? 232 ASP A N   1 
ATOM   1694 C CA  . ASP A 1 232 ? -22.11000 14.61200  -7.08700  1.000 32.90463  ? 232 ASP A CA  1 
ATOM   1695 C C   . ASP A 1 232 ? -21.44600 13.24200  -7.01700  1.000 28.44126  ? 232 ASP A C   1 
ATOM   1696 O O   . ASP A 1 232 ? -20.76700 12.82700  -7.96400  1.000 35.94434  ? 232 ASP A O   1 
ATOM   1697 C CB  . ASP A 1 232 ? -22.77900 14.80400  -8.44700  1.000 28.15260  ? 232 ASP A CB  1 
ATOM   1698 C CG  . ASP A 1 232 ? -23.82800 13.73100  -8.74400  1.000 31.48188  ? 232 ASP A CG  1 
ATOM   1699 O OD1 . ASP A 1 232 ? -23.88200 12.70100  -8.02600  1.000 30.53280  ? 232 ASP A OD1 1 
ATOM   1700 O OD2 . ASP A 1 232 ? -24.62800 13.91900  -9.69500  1.000 36.70560  ? 232 ASP A OD2 1 
ATOM   1701 N N   . LEU A 1 233 ? -21.70100 12.50100  -5.94100  1.000 24.18472  ? 233 LEU A N   1 
ATOM   1702 C CA  . LEU A 1 233 ? -21.06800 11.20500  -5.73600  1.000 26.29064  ? 233 LEU A CA  1 
ATOM   1703 C C   . LEU A 1 233 ? -21.93400 10.03600  -6.19500  1.000 28.45979  ? 233 LEU A C   1 
ATOM   1704 O O   . LEU A 1 233 ? -21.80900 8.93200   -5.64300  1.000 28.17529  ? 233 LEU A O   1 
ATOM   1705 C CB  . LEU A 1 233 ? -20.68500 11.04200  -4.27300  1.000 24.05182  ? 233 LEU A CB  1 
ATOM   1706 C CG  . LEU A 1 233 ? -19.50000 11.93100  -3.93600  1.000 23.74093  ? 233 LEU A CG  1 
ATOM   1707 C CD1 . LEU A 1 233 ? -19.08100 11.82100  -2.47700  1.000 26.89200  ? 233 LEU A CD1 1 
ATOM   1708 C CD2 . LEU A 1 233 ? -18.37900 11.56200  -4.85300  1.000 26.38604  ? 233 LEU A CD2 1 
ATOM   1709 N N   . SER A 1 234 ? -22.76100 10.23000  -7.23300  1.000 26.62326  ? 234 SER A N   1 
ATOM   1710 C CA  . SER A 1 234 ? -23.72200 9.18900   -7.61700  1.000 32.88395  ? 234 SER A CA  1 
ATOM   1711 C C   . SER A 1 234 ? -23.02600 7.92000   -8.08500  1.000 33.70788  ? 234 SER A C   1 
ATOM   1712 O O   . SER A 1 234 ? -23.41300 6.81400   -7.69700  1.000 37.87185  ? 234 SER A O   1 
ATOM   1713 C CB  . SER A 1 234 ? -24.66100 9.68200   -8.70900  1.000 23.91877  ? 234 SER A CB  1 
ATOM   1714 O OG  . SER A 1 234 ? -25.48500 10.71700  -8.21600  1.000 31.26090  ? 234 SER A OG  1 
ATOM   1715 N N   . ASN A 1 235 ? -22.01100 8.05400   -8.93400  1.000 27.06700  ? 235 ASN A N   1 
ATOM   1716 C CA  . ASN A 1 235 ? -21.30300 6.89500   -9.45700  1.000 34.35100  ? 235 ASN A CA  1 
ATOM   1717 C C   . ASN A 1 235 ? -20.04800 6.57200   -8.65600  1.000 33.20080  ? 235 ASN A C   1 
ATOM   1718 O O   . ASN A 1 235 ? -19.12100 5.95300   -9.18500  1.000 36.63796  ? 235 ASN A O   1 
ATOM   1719 C CB  . ASN A 1 235 ? -20.92600 7.11100   -10.92500 1.000 40.57246  ? 235 ASN A CB  1 
ATOM   1720 C CG  . ASN A 1 235 ? -22.09800 7.53900   -11.77600 1.000 45.17738  ? 235 ASN A CG  1 
ATOM   1721 O OD1 . ASN A 1 235 ? -23.10600 6.82300   -11.88400 1.000 40.23816  ? 235 ASN A OD1 1 
ATOM   1722 N ND2 . ASN A 1 235 ? -21.98400 8.72700   -12.37800 1.000 43.42974  ? 235 ASN A ND2 1 
ATOM   1723 N N   . SER A 1 236 ? -19.98500 6.98900   -7.40600  1.000 31.47374  ? 236 SER A N   1 
ATOM   1724 C CA  . SER A 1 236 ? -18.78300 6.81000   -6.61400  1.000 31.41593  ? 236 SER A CA  1 
ATOM   1725 C C   . SER A 1 236 ? -18.87100 5.50100   -5.84300  1.000 31.40457  ? 236 SER A C   1 
ATOM   1726 O O   . SER A 1 236 ? -19.84600 5.27200   -5.12000  1.000 26.51396  ? 236 SER A O   1 
ATOM   1727 C CB  . SER A 1 236 ? -18.62300 7.99600   -5.66000  1.000 27.50737  ? 236 SER A CB  1 
ATOM   1728 O OG  . SER A 1 236 ? -17.97100 7.60500   -4.47400  1.000 30.65881  ? 236 SER A OG  1 
ATOM   1729 N N   . ALA A 1 237 ? -17.84500 4.64900   -5.97600  1.000 32.30492  ? 237 ALA A N   1 
ATOM   1730 C CA  . ALA A 1 237 ? -17.84100 3.41000   -5.19800  1.000 28.33927  ? 237 ALA A CA  1 
ATOM   1731 C C   . ALA A 1 237 ? -17.62300 3.65700   -3.70700  1.000 31.37801  ? 237 ALA A C   1 
ATOM   1732 O O   . ALA A 1 237 ? -17.87800 2.76000   -2.89300  1.000 30.27344  ? 237 ALA A O   1 
ATOM   1733 C CB  . ALA A 1 237 ? -16.77500 2.44900   -5.72600  1.000 30.64820  ? 237 ALA A CB  1 
ATOM   1734 N N   . LEU A 1 238 ? -17.16100 4.84600   -3.32200  1.000 28.58892  ? 238 LEU A N   1 
ATOM   1735 C CA  . LEU A 1 238 ? -16.87700 5.13400   -1.92400  1.000 27.97668  ? 238 LEU A CA  1 
ATOM   1736 C C   . LEU A 1 238 ? -17.96200 5.96600   -1.25500  1.000 29.75966  ? 238 LEU A C   1 
ATOM   1737 O O   . LEU A 1 238 ? -17.78300 6.37000   -0.09300  1.000 24.80205  ? 238 LEU A O   1 
ATOM   1738 C CB  . LEU A 1 238 ? -15.52600 5.86000   -1.81200  1.000 30.55419  ? 238 LEU A CB  1 
ATOM   1739 C CG  . LEU A 1 238 ? -14.39400 5.16600   -2.57800  1.000 29.74751  ? 238 LEU A CG  1 
ATOM   1740 C CD1 . LEU A 1 238 ? -13.06600 5.90900   -2.43900  1.000 29.98380  ? 238 LEU A CD1 1 
ATOM   1741 C CD2 . LEU A 1 238 ? -14.28000 3.73500   -2.05800  1.000 26.64571  ? 238 LEU A CD2 1 
ATOM   1742 N N   . ARG A 1 239 ? -19.06500 6.25600   -1.96200  1.000 26.96093  ? 239 ARG A N   1 
ATOM   1743 C CA  . ARG A 1 239 ? -20.04800 7.19900   -1.44200  1.000 27.35675  ? 239 ARG A CA  1 
ATOM   1744 C C   . ARG A 1 239 ? -20.46700 6.76100   -0.06000  1.000 27.48932  ? 239 ARG A C   1 
ATOM   1745 O O   . ARG A 1 239 ? -20.70000 5.57500   0.17700   1.000 25.68081  ? 239 ARG A O   1 
ATOM   1746 C CB  . ARG A 1 239 ? -21.27400 7.28900   -2.35000  1.000 29.60700  ? 239 ARG A CB  1 
ATOM   1747 C CG  . ARG A 1 239 ? -22.23500 8.45100   -2.02400  1.000 27.13204  ? 239 ARG A CG  1 
ATOM   1748 C CD  . ARG A 1 239 ? -23.39100 8.44200   -3.01500  1.000 21.08547  ? 239 ARG A CD  1 
ATOM   1749 N NE  . ARG A 1 239 ? -24.03100 7.12700   -3.00200  1.000 17.95698  ? 239 ARG A NE  1 
ATOM   1750 C CZ  . ARG A 1 239 ? -24.98700 6.78700   -2.15200  1.000 21.16077  ? 239 ARG A CZ  1 
ATOM   1751 N NH1 . ARG A 1 239 ? -25.51500 7.67000   -1.31900  1.000 22.39512  ? 239 ARG A NH1 1 
ATOM   1752 N NH2 . ARG A 1 239 ? -25.40600 5.52600   -2.11400  1.000 24.94388  ? 239 ARG A NH2 1 
ATOM   1753 N N   . SER A 1 240 ? -20.46300 7.70700   0.87100   1.000 30.27228  ? 240 SER A N   1 
ATOM   1754 C CA  . SER A 1 240 ? -20.99800 7.45000   2.19400   1.000 28.12931  ? 240 SER A CA  1 
ATOM   1755 C C   . SER A 1 240 ? -22.50300 7.67300   2.14600   1.000 26.73344  ? 240 SER A C   1 
ATOM   1756 O O   . SER A 1 240 ? -22.98500 8.59900   1.48900   1.000 33.91916  ? 240 SER A O   1 
ATOM   1757 C CB  . SER A 1 240 ? -20.32500 8.35600   3.22300   1.000 31.99353  ? 240 SER A CB  1 
ATOM   1758 O OG  . SER A 1 240 ? -20.54900 7.86800   4.52900   1.000 34.80821  ? 240 SER A OG  1 
ATOM   1759 N N   . VAL A 1 241 ? -23.24800 6.79700   2.80600   1.000 33.79306  ? 241 VAL A N   1 
ATOM   1760 C CA  . VAL A 1 241 ? -24.69200 6.72400   2.63100   1.000 31.80035  ? 241 VAL A CA  1 
ATOM   1761 C C   . VAL A 1 241 ? -25.39400 7.50200   3.73300   1.000 31.36558  ? 241 VAL A C   1 
ATOM   1762 O O   . VAL A 1 241 ? -24.83400 7.78600   4.79700   1.000 32.20007  ? 241 VAL A O   1 
ATOM   1763 C CB  . VAL A 1 241 ? -25.18500 5.25500   2.59300   1.000 31.45647  ? 241 VAL A CB  1 
ATOM   1764 C CG1 . VAL A 1 241 ? -24.55000 4.53300   1.42200   1.000 30.78644  ? 241 VAL A CG1 1 
ATOM   1765 C CG2 . VAL A 1 241 ? -24.90700 4.53100   3.92300   1.000 29.16794  ? 241 VAL A CG2 1 
ATOM   1766 N N   . SER A 1 242 ? -26.64600 7.84400   3.46200   1.000 33.87222  ? 242 SER A N   1 
ATOM   1767 C CA  . SER A 1 242 ? -27.55700 8.54600   4.35100   1.000 34.77102  ? 242 SER A CA  1 
ATOM   1768 C C   . SER A 1 242 ? -27.35900 8.11300   5.79600   1.000 32.67454  ? 242 SER A C   1 
ATOM   1769 O O   . SER A 1 242 ? -27.34000 6.91500   6.09100   1.000 34.50350  ? 242 SER A O   1 
ATOM   1770 C CB  . SER A 1 242 ? -29.00000 8.28800   3.90900   1.000 32.92208  ? 242 SER A CB  1 
ATOM   1771 O OG  . SER A 1 242 ? -29.92600 8.74900   4.87100   1.000 32.61094  ? 242 SER A OG  1 
ATOM   1772 N N   . PRO A 1 243 ? -27.18000 9.05200   6.71900   1.000 36.08051  ? 243 PRO A N   1 
ATOM   1773 C CA  . PRO A 1 243 ? -27.10300 8.66500   8.14400   1.000 31.83518  ? 243 PRO A CA  1 
ATOM   1774 C C   . PRO A 1 243 ? -28.36600 7.99500   8.64200   1.000 33.40378  ? 243 PRO A C   1 
ATOM   1775 O O   . PRO A 1 243 ? -28.29700 7.16600   9.55800   1.000 30.98923  ? 243 PRO A O   1 
ATOM   1776 C CB  . PRO A 1 243 ? -26.86800 9.99700   8.86300   1.000 21.23954  ? 243 PRO A CB  1 
ATOM   1777 C CG  . PRO A 1 243 ? -26.34600 10.92400  7.78100   1.000 35.10281  ? 243 PRO A CG  1 
ATOM   1778 C CD  . PRO A 1 243 ? -27.00500 10.49900  6.50800   1.000 28.95466  ? 243 PRO A CD  1 
ATOM   1779 N N   . VAL A 1 244 ? -29.52900 8.32900   8.07700   1.000 28.95856  ? 244 VAL A N   1 
ATOM   1780 C CA  . VAL A 1 244 ? -30.73900 7.64500   8.52100   1.000 32.95361  ? 244 VAL A CA  1 
ATOM   1781 C C   . VAL A 1 244 ? -30.61900 6.15500   8.25700   1.000 35.32482  ? 244 VAL A C   1 
ATOM   1782 O O   . VAL A 1 244 ? -30.97600 5.33100   9.11000   1.000 38.51045  ? 244 VAL A O   1 
ATOM   1783 C CB  . VAL A 1 244 ? -31.98800 8.24000   7.85900   1.000 31.49423  ? 244 VAL A CB  1 
ATOM   1784 C CG1 . VAL A 1 244 ? -33.16300 7.35600   8.14900   1.000 35.89805  ? 244 VAL A CG1 1 
ATOM   1785 C CG2 . VAL A 1 244 ? -32.24700 9.61200   8.41100   1.000 34.34903  ? 244 VAL A CG2 1 
ATOM   1786 N N   . HIS A 1 245 ? -30.05300 5.78100   7.10300   1.000 33.77134  ? 245 HIS A N   1 
ATOM   1787 C CA  . HIS A 1 245 ? -29.85400 4.36100   6.81800   1.000 33.28364  ? 245 HIS A CA  1 
ATOM   1788 C C   . HIS A 1 245 ? -28.80200 3.74300   7.73900   1.000 35.69876  ? 245 HIS A C   1 
ATOM   1789 O O   . HIS A 1 245 ? -28.98300 2.61800   8.22000   1.000 34.39797  ? 245 HIS A O   1 
ATOM   1790 C CB  . HIS A 1 245 ? -29.47600 4.13600   5.34900   1.000 31.63530  ? 245 HIS A CB  1 
ATOM   1791 C CG  . HIS A 1 245 ? -29.32000 2.68700   4.99800   1.000 34.06030  ? 245 HIS A CG  1 
ATOM   1792 N ND1 . HIS A 1 245 ? -30.28700 1.74600   5.28900   1.000 29.77592  ? 245 HIS A ND1 1 
ATOM   1793 C CD2 . HIS A 1 245 ? -28.29500 2.00800   4.43000   1.000 32.98361  ? 245 HIS A CD2 1 
ATOM   1794 C CE1 . HIS A 1 245 ? -29.86800 0.55300   4.90900   1.000 28.87642  ? 245 HIS A CE1 1 
ATOM   1795 N NE2 . HIS A 1 245 ? -28.66000 0.68300   4.38900   1.000 31.88270  ? 245 HIS A NE2 1 
ATOM   1796 N N   . LEU A 1 246 ? -27.69900 4.45300   8.00500   1.000 34.87747  ? 246 LEU A N   1 
ATOM   1797 C CA  . LEU A 1 246 ? -26.67000 3.89900   8.88900   1.000 35.28491  ? 246 LEU A CA  1 
ATOM   1798 C C   . LEU A 1 246 ? -27.23800 3.59100   10.27100  1.000 39.58413  ? 246 LEU A C   1 
ATOM   1799 O O   . LEU A 1 246 ? -26.85400 2.60200   10.91300  1.000 41.20044  ? 246 LEU A O   1 
ATOM   1800 C CB  . LEU A 1 246 ? -25.49300 4.86900   9.00100   1.000 36.02354  ? 246 LEU A CB  1 
ATOM   1801 C CG  . LEU A 1 246 ? -24.62800 4.97600   7.74700   1.000 35.93981  ? 246 LEU A CG  1 
ATOM   1802 C CD1 . LEU A 1 246 ? -23.75400 6.25000   7.74200   1.000 30.47469  ? 246 LEU A CD1 1 
ATOM   1803 C CD2 . LEU A 1 246 ? -23.77200 3.73000   7.60900   1.000 35.47394  ? 246 LEU A CD2 1 
ATOM   1804 N N   . GLU A 1 247 ? -28.14500 4.44300   10.74700  1.000 41.46547  ? 247 GLU A N   1 
ATOM   1805 C CA  . GLU A 1 247 ? -28.85000 4.18400   11.99600  1.000 39.30559  ? 247 GLU A CA  1 
ATOM   1806 C C   . GLU A 1 247 ? -29.78900 2.98900   11.85800  1.000 39.95508  ? 247 GLU A C   1 
ATOM   1807 O O   . GLU A 1 247 ? -29.86100 2.13500   12.75100  1.000 36.45028  ? 247 GLU A O   1 
ATOM   1808 C CB  . GLU A 1 247 ? -29.61000 5.44200   12.37700  1.000 35.95527  ? 247 GLU A CB  1 
ATOM   1809 C CG  . GLU A 1 247 ? -30.07300 5.51400   13.78300  1.000 41.16803  ? 247 GLU A CG  1 
ATOM   1810 C CD  . GLU A 1 247 ? -30.63000 6.88000   14.06700  1.000 39.13038  ? 247 GLU A CD  1 
ATOM   1811 O OE1 . GLU A 1 247 ? -30.22100 7.82200   13.35900  1.000 39.59957  ? 247 GLU A OE1 1 
ATOM   1812 O OE2 . GLU A 1 247 ? -31.48400 7.01100   14.96400  1.000 45.20211  ? 247 GLU A OE2 1 
ATOM   1813 N N   . TYR A 1 248 ? -30.51900 2.91700   10.73600  1.000 37.30899  ? 248 TYR A N   1 
ATOM   1814 C CA  . TYR A 1 248 ? -31.33500 1.74900   10.43100  1.000 32.16083  ? 248 TYR A CA  1 
ATOM   1815 C C   . TYR A 1 248 ? -30.51200 0.47800   10.57700  1.000 33.32102  ? 248 TYR A C   1 
ATOM   1816 O O   . TYR A 1 248 ? -30.88500 -0.43400  11.32200  1.000 31.18023  ? 248 TYR A O   1 
ATOM   1817 C CB  . TYR A 1 248 ? -31.91800 1.90300   9.01600   1.000 37.03028  ? 248 TYR A CB  1 
ATOM   1818 C CG  . TYR A 1 248 ? -32.88500 0.82900   8.48600   1.000 36.72734  ? 248 TYR A CG  1 
ATOM   1819 C CD1 . TYR A 1 248 ? -32.42000 -0.41000  8.06300   1.000 32.66681  ? 248 TYR A CD1 1 
ATOM   1820 C CD2 . TYR A 1 248 ? -34.25500 1.10700   8.31700   1.000 35.27559  ? 248 TYR A CD2 1 
ATOM   1821 C CE1 . TYR A 1 248 ? -33.29200 -1.36900  7.54100   1.000 35.09485  ? 248 TYR A CE1 1 
ATOM   1822 C CE2 . TYR A 1 248 ? -35.13000 0.15100   7.79200   1.000 37.05579  ? 248 TYR A CE2 1 
ATOM   1823 C CZ  . TYR A 1 248 ? -34.63100 -1.09300  7.41800   1.000 35.48125  ? 248 TYR A CZ  1 
ATOM   1824 O OH  . TYR A 1 248 ? -35.45000 -2.06100  6.89900   1.000 29.78108  ? 248 TYR A OH  1 
ATOM   1825 N N   . LEU A 1 249 ? -29.34900 0.43000   9.92400   1.000 34.83509  ? 249 LEU A N   1 
ATOM   1826 C CA  . LEU A 1 249 ? -28.51300 -0.76700  9.97800   1.000 31.79822  ? 249 LEU A CA  1 
ATOM   1827 C C   . LEU A 1 249 ? -28.08600 -1.09600  11.40500  1.000 36.91850  ? 249 LEU A C   1 
ATOM   1828 O O   . LEU A 1 249 ? -28.11300 -2.26700  11.81500  1.000 36.54493  ? 249 LEU A O   1 
ATOM   1829 C CB  . LEU A 1 249 ? -27.28900 -0.58900  9.08400   1.000 32.73000  ? 249 LEU A CB  1 
ATOM   1830 C CG  . LEU A 1 249 ? -27.54700 -0.69100  7.57600   1.000 33.87985  ? 249 LEU A CG  1 
ATOM   1831 C CD1 . LEU A 1 249 ? -26.28200 -0.36300  6.78300   1.000 31.37167  ? 249 LEU A CD1 1 
ATOM   1832 C CD2 . LEU A 1 249 ? -28.09400 -2.07600  7.21000   1.000 31.05621  ? 249 LEU A CD2 1 
ATOM   1833 N N   . ARG A 1 250 ? -27.69000 -0.08500  12.18100  1.000 35.42625  ? 250 ARG A N   1 
ATOM   1834 C CA  . ARG A 1 250 ? -27.23400 -0.36700  13.53900  1.000 39.88352  ? 250 ARG A CA  1 
ATOM   1835 C C   . ARG A 1 250 ? -28.37900 -0.88000  14.39700  1.000 37.01609  ? 250 ARG A C   1 
ATOM   1836 O O   . ARG A 1 250 ? -28.21900 -1.86100  15.13700  1.000 36.26910  ? 250 ARG A O   1 
ATOM   1837 C CB  . ARG A 1 250 ? -26.58800 0.87500   14.15700  1.000 40.02461  ? 250 ARG A CB  1 
ATOM   1838 C CG  . ARG A 1 250 ? -25.23900 1.24700   13.51900  1.000 38.68836  ? 250 ARG A CG  1 
ATOM   1839 C CD  . ARG A 1 250 ? -24.52600 2.34300   14.31900  1.000 49.68808  ? 250 ARG A CD  1 
ATOM   1840 N NE  . ARG A 1 250 ? -25.32500 3.56100   14.43500  1.000 51.83242  ? 250 ARG A NE  1 
ATOM   1841 C CZ  . ARG A 1 250 ? -25.15200 4.65100   13.69400  1.000 52.50874  ? 250 ARG A CZ  1 
ATOM   1842 N NH1 . ARG A 1 250 ? -24.16900 4.74000   12.80900  1.000 43.43562  ? 250 ARG A NH1 1 
ATOM   1843 N NH2 . ARG A 1 250 ? -25.99100 5.67900   13.84200  1.000 49.02163  ? 250 ARG A NH2 1 
ATOM   1844 N N   . ASN A 1 251 ? -29.55000 -0.24800  14.28900  1.000 37.26434  ? 251 ASN A N   1 
ATOM   1845 C CA  . ASN A 1 251 ? -30.74500 -0.77400  14.94000  1.000 33.52404  ? 251 ASN A CA  1 
ATOM   1846 C C   . ASN A 1 251 ? -31.02300 -2.21700  14.54700  1.000 35.85854  ? 251 ASN A C   1 
ATOM   1847 O O   . ASN A 1 251 ? -31.49700 -3.00500  15.37200  1.000 41.53115  ? 251 ASN A O   1 
ATOM   1848 C CB  . ASN A 1 251 ? -31.93600 0.10300   14.59800  1.000 37.71920  ? 251 ASN A CB  1 
ATOM   1849 C CG  . ASN A 1 251 ? -31.84500 1.45200   15.24300  1.000 37.17412  ? 251 ASN A CG  1 
ATOM   1850 O OD1 . ASN A 1 251 ? -30.86700 1.75800   15.93500  1.000 35.14066  ? 251 ASN A OD1 1 
ATOM   1851 N ND2 . ASN A 1 251 ? -32.86000 2.27700   15.02400  1.000 42.01536  ? 251 ASN A ND2 1 
ATOM   1852 N N   . MET A 1 252 ? -30.72600 -2.58900  13.30500  1.000 35.90400  ? 252 MET A N   1 
ATOM   1853 C CA  . MET A 1 252 ? -30.88100 -3.97100  12.87200  1.000 38.14880  ? 252 MET A CA  1 
ATOM   1854 C C   . MET A 1 252 ? -29.76200 -4.85700  13.39600  1.000 39.30882  ? 252 MET A C   1 
ATOM   1855 O O   . MET A 1 252 ? -29.84200 -6.08200  13.25900  1.000 38.96359  ? 252 MET A O   1 
ATOM   1856 C CB  . MET A 1 252 ? -30.93600 -4.03200  11.33900  1.000 34.63443  ? 252 MET A CB  1 
ATOM   1857 C CG  . MET A 1 252 ? -31.54400 -5.28700  10.74200  1.000 43.54376  ? 252 MET A CG  1 
ATOM   1858 S SD  . MET A 1 252 ? -32.26600 -4.97800  9.10800   1.000 51.32737  ? 252 MET A SD  1 
ATOM   1859 C CE  . MET A 1 252 ? -31.16700 -3.68500  8.54600   1.000 43.09068  ? 252 MET A CE  1 
ATOM   1860 N N   . GLY A 1 253 ? -28.73200 -4.27000  14.00400  1.000 40.04959  ? 253 GLY A N   1 
ATOM   1861 C CA  . GLY A 1 253 ? -27.59900 -5.04800  14.46700  1.000 37.66212  ? 253 GLY A CA  1 
ATOM   1862 C C   . GLY A 1 253 ? -26.65800 -5.50400  13.37500  1.000 43.21516  ? 253 GLY A C   1 
ATOM   1863 O O   . GLY A 1 253 ? -25.92600 -6.47900  13.58300  1.000 41.71472  ? 253 GLY A O   1 
ATOM   1864 N N   . VAL A 1 254 ? -26.63900 -4.80400  12.22500  1.000 39.21407  ? 254 VAL A N   1 
ATOM   1865 C CA  . VAL A 1 254 ? -25.81100 -5.13700  11.06500  1.000 37.54057  ? 254 VAL A CA  1 
ATOM   1866 C C   . VAL A 1 254 ? -24.53400 -4.30300  11.12100  1.000 33.93711  ? 254 VAL A C   1 
ATOM   1867 O O   . VAL A 1 254 ? -24.59400 -3.09600  11.36900  1.000 34.68343  ? 254 VAL A O   1 
ATOM   1868 C CB  . VAL A 1 254 ? -26.58800 -4.87500  9.76000   1.000 34.45030  ? 254 VAL A CB  1 
ATOM   1869 C CG1 . VAL A 1 254 ? -25.80100 -5.29600  8.54100   1.000 32.79590  ? 254 VAL A CG1 1 
ATOM   1870 C CG2 . VAL A 1 254 ? -27.92900 -5.59700  9.78100   1.000 41.31663  ? 254 VAL A CG2 1 
ATOM   1871 N N   . GLY A 1 255 ? -23.37400 -4.93600  10.88100  1.000 40.56863  ? 255 GLY A N   1 
ATOM   1872 C CA  . GLY A 1 255 ? -22.08400 -4.24600  10.94600  1.000 32.89888  ? 255 GLY A CA  1 
ATOM   1873 C C   . GLY A 1 255 ? -21.49100 -3.83800  9.60100   1.000 38.37756  ? 255 GLY A C   1 
ATOM   1874 O O   . GLY A 1 255 ? -20.75900 -2.84600  9.49100   1.000 36.38567  ? 255 GLY A O   1 
ATOM   1875 N N   . ALA A 1 256 ? -21.79700 -4.61300  8.56400   1.000 37.39222  ? 256 ALA A N   1 
ATOM   1876 C CA  . ALA A 1 256 ? -21.48700 -4.26600  7.18600   1.000 31.90033  ? 256 ALA A CA  1 
ATOM   1877 C C   . ALA A 1 256 ? -22.66600 -4.66600  6.31100   1.000 32.39222  ? 256 ALA A C   1 
ATOM   1878 O O   . ALA A 1 256 ? -23.36700 -5.64400  6.60000   1.000 28.97995  ? 256 ALA A O   1 
ATOM   1879 C CB  . ALA A 1 256 ? -20.20900 -4.95400  6.69700   1.000 28.56929  ? 256 ALA A CB  1 
ATOM   1880 N N   . SER A 1 257 ? -22.87500 -3.91500  5.22700   1.000 29.61525  ? 257 SER A N   1 
ATOM   1881 C CA  . SER A 1 257 ? -24.01300 -4.14900  4.34500   1.000 22.61140  ? 257 SER A CA  1 
ATOM   1882 C C   . SER A 1 257 ? -23.61200 -3.98600  2.88400   1.000 26.41878  ? 257 SER A C   1 
ATOM   1883 O O   . SER A 1 257 ? -22.85300 -3.07700  2.52100   1.000 27.38335  ? 257 SER A O   1 
ATOM   1884 C CB  . SER A 1 257 ? -25.15300 -3.19900  4.67800   1.000 25.63426  ? 257 SER A CB  1 
ATOM   1885 O OG  . SER A 1 257 ? -26.31500 -3.60400  4.01700   1.000 27.22930  ? 257 SER A OG  1 
ATOM   1886 N N   . PHE A 1 258 ? -24.13500 -4.87000  2.04400   1.000 29.64322  ? 258 PHE A N   1 
ATOM   1887 C CA  . PHE A 1 258 ? -23.84600 -4.85500  0.61700   1.000 26.29177  ? 258 PHE A CA  1 
ATOM   1888 C C   . PHE A 1 258 ? -25.09400 -5.32300  -0.10500  1.000 26.13457  ? 258 PHE A C   1 
ATOM   1889 O O   . PHE A 1 258 ? -25.68900 -6.32400  0.29000   1.000 31.18909  ? 258 PHE A O   1 
ATOM   1890 C CB  . PHE A 1 258 ? -22.65900 -5.76200  0.28400   1.000 27.77696  ? 258 PHE A CB  1 
ATOM   1891 C CG  . PHE A 1 258 ? -22.43200 -5.94300  -1.18800  1.000 31.19306  ? 258 PHE A CG  1 
ATOM   1892 C CD1 . PHE A 1 258 ? -22.09200 -4.87000  -1.98400  1.000 31.83278  ? 258 PHE A CD1 1 
ATOM   1893 C CD2 . PHE A 1 258 ? -22.54700 -7.19100  -1.77600  1.000 34.33350  ? 258 PHE A CD2 1 
ATOM   1894 C CE1 . PHE A 1 258 ? -21.87200 -5.03900  -3.34400  1.000 29.78028  ? 258 PHE A CE1 1 
ATOM   1895 C CE2 . PHE A 1 258 ? -22.33100 -7.36100  -3.13500  1.000 30.24528  ? 258 PHE A CE2 1 
ATOM   1896 C CZ  . PHE A 1 258 ? -21.99300 -6.28200  -3.91400  1.000 27.89680  ? 258 PHE A CZ  1 
ATOM   1897 N N   . SER A 1 259 ? -25.51200 -4.60700  -1.13400  1.000 26.96044  ? 259 SER A N   1 
ATOM   1898 C CA  . SER A 1 259 ? -26.73200 -4.99400  -1.82400  1.000 29.48418  ? 259 SER A CA  1 
ATOM   1899 C C   . SER A 1 259 ? -26.55600 -4.73600  -3.30600  1.000 32.64327  ? 259 SER A C   1 
ATOM   1900 O O   . SER A 1 259 ? -25.76000 -3.88200  -3.70700  1.000 32.01082  ? 259 SER A O   1 
ATOM   1901 C CB  . SER A 1 259 ? -27.96600 -4.23800  -1.31000  1.000 30.75267  ? 259 SER A CB  1 
ATOM   1902 O OG  . SER A 1 259 ? -28.05400 -2.94800  -1.90100  1.000 30.68663  ? 259 SER A OG  1 
ATOM   1903 N N   . LEU A 1 260 ? -27.30300 -5.49000  -4.11600  1.000 29.51807  ? 260 LEU A N   1 
ATOM   1904 C CA  . LEU A 1 260 ? -27.27000 -5.36100  -5.56500  1.000 29.11101  ? 260 LEU A CA  1 
ATOM   1905 C C   . LEU A 1 260 ? -28.69000 -5.22200  -6.08900  1.000 30.33365  ? 260 LEU A C   1 
ATOM   1906 O O   . LEU A 1 260 ? -29.63200 -5.76600  -5.50600  1.000 29.04395  ? 260 LEU A O   1 
ATOM   1907 C CB  . LEU A 1 260 ? -26.59300 -6.56200  -6.23700  1.000 33.34289  ? 260 LEU A CB  1 
ATOM   1908 C CG  . LEU A 1 260 ? -25.24900 -7.04100  -5.68300  1.000 33.96561  ? 260 LEU A CG  1 
ATOM   1909 C CD1 . LEU A 1 260 ? -25.43800 -7.98400  -4.48700  1.000 29.98892  ? 260 LEU A CD1 1 
ATOM   1910 C CD2 . LEU A 1 260 ? -24.47100 -7.71500  -6.77400  1.000 34.77239  ? 260 LEU A CD2 1 
ATOM   1911 N N   . SER A 1 261 ? -28.83800 -4.48600  -7.19300  1.000 30.26668  ? 261 SER A N   1 
ATOM   1912 C CA  . SER A 1 261 ? -30.14800 -4.22200  -7.77500  1.000 32.19385  ? 261 SER A CA  1 
ATOM   1913 C C   . SER A 1 261 ? -30.51500 -5.33000  -8.74800  1.000 32.18097  ? 261 SER A C   1 
ATOM   1914 O O   . SER A 1 261 ? -29.72500 -5.68800  -9.62700  1.000 38.96217  ? 261 SER A O   1 
ATOM   1915 C CB  . SER A 1 261 ? -30.17700 -2.86700  -8.48100  1.000 30.19981  ? 261 SER A CB  1 
ATOM   1916 O OG  . SER A 1 261 ? -30.27700 -1.80400  -7.54000  1.000 31.27277  ? 261 SER A OG  1 
ATOM   1917 N N   . LEU A 1 262 ? -31.70400 -5.88200  -8.58000  1.000 30.63622  ? 262 LEU A N   1 
ATOM   1918 C CA  . LEU A 1 262 ? -32.22700 -6.86300  -9.52300  1.000 35.71105  ? 262 LEU A CA  1 
ATOM   1919 C C   . LEU A 1 262 ? -33.03700 -6.09500  -10.55400 1.000 35.73550  ? 262 LEU A C   1 
ATOM   1920 O O   . LEU A 1 262 ? -34.16100 -5.68100  -10.28100 1.000 34.94482  ? 262 LEU A O   1 
ATOM   1921 C CB  . LEU A 1 262 ? -33.07800 -7.90000  -8.80900  1.000 40.33205  ? 262 LEU A CB  1 
ATOM   1922 C CG  . LEU A 1 262 ? -32.61600 -9.34800  -8.87500  1.000 40.85850  ? 262 LEU A CG  1 
ATOM   1923 C CD1 . LEU A 1 262 ? -31.10900 -9.39200  -8.86900  1.000 43.49881  ? 262 LEU A CD1 1 
ATOM   1924 C CD2 . LEU A 1 262 ? -33.17100 -10.08200 -7.66800  1.000 36.44892  ? 262 LEU A CD2 1 
ATOM   1925 N N   . LEU A 1 263 ? -32.45800 -5.88800  -11.73500 1.000 39.20184  ? 263 LEU A N   1 
ATOM   1926 C CA  . LEU A 1 263 ? -33.11000 -5.17800  -12.82900 1.000 46.19810  ? 263 LEU A CA  1 
ATOM   1927 C C   . LEU A 1 263 ? -33.67600 -6.19900  -13.81700 1.000 45.48551  ? 263 LEU A C   1 
ATOM   1928 O O   . LEU A 1 263 ? -32.93500 -7.03100  -14.35300 1.000 47.76022  ? 263 LEU A O   1 
ATOM   1929 C CB  . LEU A 1 263 ? -32.11800 -4.22800  -13.50100 1.000 44.29395  ? 263 LEU A CB  1 
ATOM   1930 C CG  . LEU A 1 263 ? -31.44100 -3.24300  -12.52600 1.000 47.71587  ? 263 LEU A CG  1 
ATOM   1931 C CD1 . LEU A 1 263 ? -29.91700 -3.24000  -12.69500 1.000 42.26304  ? 263 LEU A CD1 1 
ATOM   1932 C CD2 . LEU A 1 263 ? -31.99800 -1.83100  -12.65200 1.000 39.66585  ? 263 LEU A CD2 1 
ATOM   1933 N N   . LYS A 1 264 ? -34.99000 -6.15900  -14.03100 1.000 47.31918  ? 264 LYS A N   1 
ATOM   1934 C CA  . LYS A 1 264 ? -35.67500 -7.14500  -14.86400 1.000 50.88991  ? 264 LYS A CA  1 
ATOM   1935 C C   . LYS A 1 264 ? -36.50400 -6.40700  -15.90600 1.000 54.55420  ? 264 LYS A C   1 
ATOM   1936 O O   . LYS A 1 264 ? -37.50500 -5.76200  -15.56500 1.000 53.07299  ? 264 LYS A O   1 
ATOM   1937 C CB  . LYS A 1 264 ? -36.54900 -8.08000  -14.02400 1.000 46.64584  ? 264 LYS A CB  1 
ATOM   1938 C CG  . LYS A 1 264 ? -37.15200 -9.23900  -14.81200 1.000 51.40453  ? 264 LYS A CG  1 
ATOM   1939 C CD  . LYS A 1 264 ? -37.77700 -10.26500 -13.88000 1.000 50.11536  ? 264 LYS A CD  1 
ATOM   1940 C CE  . LYS A 1 264 ? -38.87400 -11.04500 -14.57900 1.000 55.98862  ? 264 LYS A CE  1 
ATOM   1941 N NZ  . LYS A 1 264 ? -39.99800 -10.16700 -14.99900 1.000 62.43463  ? 264 LYS A NZ  1 
ATOM   1942 N N   . GLU A 1 265 ? -36.08800 -6.51700  -17.17500 1.000 58.13327  ? 265 GLU A N   1 
ATOM   1943 C CA  . GLU A 1 265 ? -36.72700 -5.81500  -18.29600 1.000 61.28394  ? 265 GLU A CA  1 
ATOM   1944 C C   . GLU A 1 265 ? -36.76200 -4.30700  -18.05000 1.000 53.61337  ? 265 GLU A C   1 
ATOM   1945 O O   . GLU A 1 265 ? -37.70200 -3.61700  -18.45500 1.000 50.79255  ? 265 GLU A O   1 
ATOM   1946 C CB  . GLU A 1 265 ? -38.13300 -6.36500  -18.58400 1.000 60.10795  ? 265 GLU A CB  1 
ATOM   1947 C CG  . GLU A 1 265 ? -38.15400 -7.86200  -18.95200 1.000 62.98733  ? 265 GLU A CG  1 
ATOM   1948 C CD  . GLU A 1 265 ? -39.28800 -8.62400  -18.26400 1.000 68.01660  ? 265 GLU A CD  1 
ATOM   1949 O OE1 . GLU A 1 265 ? -40.29900 -7.97400  -17.91800 1.000 72.13347  ? 265 GLU A OE1 1 
ATOM   1950 O OE2 . GLU A 1 265 ? -39.16900 -9.86100  -18.05900 1.000 62.87164  ? 265 GLU A OE2 1 
ATOM   1951 N N   . GLY A 1 266 ? -35.72400 -3.80000  -17.37300 1.000 52.64757  ? 266 GLY A N   1 
ATOM   1952 C CA  . GLY A 1 266 ? -35.48500 -2.38100  -17.23400 1.000 48.20807  ? 266 GLY A CA  1 
ATOM   1953 C C   . GLY A 1 266 ? -36.03400 -1.74600  -15.97600 1.000 51.44212  ? 266 GLY A C   1 
ATOM   1954 O O   . GLY A 1 266 ? -35.66300 -0.60600  -15.67000 1.000 55.34840  ? 266 GLY A O   1 
ATOM   1955 N N   . VAL A 1 267 ? -36.90600 -2.42800  -15.23800 1.000 50.69038  ? 267 VAL A N   1 
ATOM   1956 C CA  . VAL A 1 267 ? -37.48400 -1.86500  -14.02800 1.000 44.92352  ? 267 VAL A CA  1 
ATOM   1957 C C   . VAL A 1 267 ? -36.91400 -2.59400  -12.82400 1.000 45.22077  ? 267 VAL A C   1 
ATOM   1958 O O   . VAL A 1 267 ? -36.36300 -3.69600  -12.93100 1.000 47.10922  ? 267 VAL A O   1 
ATOM   1959 C CB  . VAL A 1 267 ? -39.02200 -1.92200  -14.03000 1.000 48.67665  ? 267 VAL A CB  1 
ATOM   1960 C CG1 . VAL A 1 267 ? -39.56400 -1.00500  -15.11700 1.000 50.72362  ? 267 VAL A CG1 1 
ATOM   1961 C CG2 . VAL A 1 267 ? -39.49000 -3.34800  -14.23600 1.000 40.09961  ? 267 VAL A CG2 1 
ATOM   1962 N N   . LEU A 1 268 ? -37.03800 -1.94600  -11.66100 1.000 46.02717  ? 268 LEU A N   1 
ATOM   1963 C CA  . LEU A 1 268 ? -36.39700 -2.38000  -10.41900 1.000 37.79466  ? 268 LEU A CA  1 
ATOM   1964 C C   . LEU A 1 268 ? -37.27600 -3.43900  -9.78100  1.000 38.77030  ? 268 LEU A C   1 
ATOM   1965 O O   . LEU A 1 268 ? -38.25600 -3.12500  -9.10800  1.000 49.87901  ? 268 LEU A O   1 
ATOM   1966 C CB  . LEU A 1 268 ? -36.18000 -1.19200  -9.48800  1.000 38.47670  ? 268 LEU A CB  1 
ATOM   1967 C CG  . LEU A 1 268 ? -35.39800 -1.34200  -8.17200  1.000 40.71809  ? 268 LEU A CG  1 
ATOM   1968 C CD1 . LEU A 1 268 ? -34.00700 -1.97100  -8.37600  1.000 34.67388  ? 268 LEU A CD1 1 
ATOM   1969 C CD2 . LEU A 1 268 ? -35.28000 0.01200   -7.44900  1.000 31.35866  ? 268 LEU A CD2 1 
ATOM   1970 N N   . TRP A 1 269 ? -36.93300 -4.70400  -10.00500 1.000 38.13636  ? 269 TRP A N   1 
ATOM   1971 C CA  . TRP A 1 269 ? -37.73600 -5.81500  -9.51300  1.000 31.98000  ? 269 TRP A CA  1 
ATOM   1972 C C   . TRP A 1 269 ? -37.53600 -6.04900  -8.02200  1.000 36.90448  ? 269 TRP A C   1 
ATOM   1973 O O   . TRP A 1 269 ? -38.46400 -6.49600  -7.32900  1.000 35.50778  ? 269 TRP A O   1 
ATOM   1974 C CB  . TRP A 1 269 ? -37.36700 -7.06800  -10.30900 1.000 31.53975  ? 269 TRP A CB  1 
ATOM   1975 C CG  . TRP A 1 269 ? -38.19000 -8.27400  -10.02300 1.000 33.84102  ? 269 TRP A CG  1 
ATOM   1976 C CD1 . TRP A 1 269 ? -39.38000 -8.60700  -10.60200 1.000 35.32233  ? 269 TRP A CD1 1 
ATOM   1977 C CD2 . TRP A 1 269 ? -37.87100 -9.33900  -9.11500  1.000 33.43572  ? 269 TRP A CD2 1 
ATOM   1978 N NE1 . TRP A 1 269 ? -39.82700 -9.81200  -10.10400 1.000 42.95069  ? 269 TRP A NE1 1 
ATOM   1979 C CE2 . TRP A 1 269 ? -38.92000 -10.27800 -9.18900  1.000 37.48738  ? 269 TRP A CE2 1 
ATOM   1980 C CE3 . TRP A 1 269 ? -36.81200 -9.58000  -8.23300  1.000 33.65155  ? 269 TRP A CE3 1 
ATOM   1981 C CZ2 . TRP A 1 269 ? -38.93900 -11.43500 -8.41600  1.000 41.98017  ? 269 TRP A CZ2 1 
ATOM   1982 C CZ3 . TRP A 1 269 ? -36.82500 -10.73300 -7.47200  1.000 36.17630  ? 269 TRP A CZ3 1 
ATOM   1983 C CH2 . TRP A 1 269 ? -37.88600 -11.64500 -7.56200  1.000 41.12453  ? 269 TRP A CH2 1 
ATOM   1984 N N   . GLY A 1 270 ? -36.34300 -5.74900  -7.51700  1.000 37.77661  ? 270 GLY A N   1 
ATOM   1985 C CA  . GLY A 1 270 ? -36.01100 -6.04400  -6.13300  1.000 30.81651  ? 270 GLY A CA  1 
ATOM   1986 C C   . GLY A 1 270 ? -34.52300 -5.85000  -5.88700  1.000 33.86624  ? 270 GLY A C   1 
ATOM   1987 O O   . GLY A 1 270 ? -33.85400 -5.08800  -6.59200  1.000 34.01899  ? 270 GLY A O   1 
ATOM   1988 N N   . LEU A 1 271 ? -34.02400 -6.55800  -4.87800  1.000 33.10836  ? 271 LEU A N   1 
ATOM   1989 C CA  . LEU A 1 271 ? -32.63700 -6.44700  -4.45300  1.000 31.68857  ? 271 LEU A CA  1 
ATOM   1990 C C   . LEU A 1 271 ? -32.18500 -7.79400  -3.93100  1.000 34.74586  ? 271 LEU A C   1 
ATOM   1991 O O   . LEU A 1 271 ? -32.99300 -8.57400  -3.41500  1.000 37.44152  ? 271 LEU A O   1 
ATOM   1992 C CB  . LEU A 1 271 ? -32.44200 -5.42800  -3.32100  1.000 28.24554  ? 271 LEU A CB  1 
ATOM   1993 C CG  . LEU A 1 271 ? -32.84500 -3.97500  -3.46400  1.000 30.42700  ? 271 LEU A CG  1 
ATOM   1994 C CD1 . LEU A 1 271 ? -32.93000 -3.43500  -2.07400  1.000 37.86025  ? 271 LEU A CD1 1 
ATOM   1995 C CD2 . LEU A 1 271 ? -31.82700 -3.20000  -4.27700  1.000 28.52343  ? 271 LEU A CD2 1 
ATOM   1996 N N   . ILE A 1 272 ? -30.89000 -8.05300  -4.05000  1.000 31.56399  ? 272 ILE A N   1 
ATOM   1997 C CA  . ILE A 1 272 ? -30.22600 -9.04000  -3.21200  1.000 32.46807  ? 272 ILE A CA  1 
ATOM   1998 C C   . ILE A 1 272 ? -29.46100 -8.25800  -2.15400  1.000 33.46085  ? 272 ILE A C   1 
ATOM   1999 O O   . ILE A 1 272 ? -28.55600 -7.47600  -2.48300  1.000 33.87734  ? 272 ILE A O   1 
ATOM   2000 C CB  . ILE A 1 272 ? -29.31300 -9.96100  -4.03200  1.000 34.40948  ? 272 ILE A CB  1 
ATOM   2001 C CG1 . ILE A 1 272 ? -30.17000 -10.84800 -4.93900  1.000 36.14504  ? 272 ILE A CG1 1 
ATOM   2002 C CG2 . ILE A 1 272 ? -28.48400 -10.84900 -3.11700  1.000 30.22512  ? 272 ILE A CG2 1 
ATOM   2003 C CD1 . ILE A 1 272 ? -29.38800 -11.55700 -6.01500  1.000 35.97444  ? 272 ILE A CD1 1 
ATOM   2004 N N   . ALA A 1 273 ? -29.86600 -8.42100  -0.89200  1.000 30.11820  ? 273 ALA A N   1 
ATOM   2005 C CA  . ALA A 1 273 ? -29.35200 -7.64000  0.22600   1.000 31.45036  ? 273 ALA A CA  1 
ATOM   2006 C C   . ALA A 1 273 ? -28.48000 -8.52300  1.11000   1.000 37.13846  ? 273 ALA A C   1 
ATOM   2007 O O   . ALA A 1 273 ? -28.91800 -9.59600  1.54500   1.000 34.83893  ? 273 ALA A O   1 
ATOM   2008 C CB  . ALA A 1 273 ? -30.49800 -7.06000  1.05500   1.000 27.52950  ? 273 ALA A CB  1 
ATOM   2009 N N   . CYS A 1 274 ? -27.26900 -8.05900  1.40500   1.000 34.52084  ? 274 CYS A N   1 
ATOM   2010 C CA  . CYS A 1 274 ? -26.31300 -8.81300  2.20600   1.000 30.43019  ? 274 CYS A CA  1 
ATOM   2011 C C   . CYS A 1 274 ? -26.00300 -8.06300  3.49900   1.000 35.32304  ? 274 CYS A C   1 
ATOM   2012 O O   . CYS A 1 274 ? -25.71600 -6.85700  3.47300   1.000 32.32127  ? 274 CYS A O   1 
ATOM   2013 C CB  . CYS A 1 274 ? -25.03400 -9.07300  1.41100   1.000 28.12251  ? 274 CYS A CB  1 
ATOM   2014 S SG  . CYS A 1 274 ? -25.31300 -9.86400  -0.18700  1.000 28.81015  ? 274 CYS A SG  1 
ATOM   2015 N N   . HIS A 1 275 ? -26.08800 -8.77500  4.62400   1.000 35.86524  ? 275 HIS A N   1 
ATOM   2016 C CA  . HIS A 1 275 ? -25.71800 -8.26500  5.93800   1.000 32.58966  ? 275 HIS A CA  1 
ATOM   2017 C C   . HIS A 1 275 ? -24.53600 -9.05800  6.47000   1.000 36.62047  ? 275 HIS A C   1 
ATOM   2018 O O   . HIS A 1 275 ? -24.44800 -10.27400 6.25000   1.000 37.22194  ? 275 HIS A O   1 
ATOM   2019 C CB  . HIS A 1 275 ? -26.86600 -8.38200  6.93900   1.000 31.63134  ? 275 HIS A CB  1 
ATOM   2020 C CG  . HIS A 1 275 ? -28.04500 -7.51500  6.62800   1.000 34.66422  ? 275 HIS A CG  1 
ATOM   2021 N ND1 . HIS A 1 275 ? -29.28700 -7.73100  7.18600   1.000 38.54061  ? 275 HIS A ND1 1 
ATOM   2022 C CD2 . HIS A 1 275 ? -28.17000 -6.41900  5.84000   1.000 34.60736  ? 275 HIS A CD2 1 
ATOM   2023 C CE1 . HIS A 1 275 ? -30.13000 -6.81100  6.75000   1.000 40.72133  ? 275 HIS A CE1 1 
ATOM   2024 N NE2 . HIS A 1 275 ? -29.47800 -6.00200  5.93300   1.000 37.67661  ? 275 HIS A NE2 1 
ATOM   2025 N N   . HIS A 1 276 ? -23.62300 -8.36400  7.15400   1.000 33.92322  ? 276 HIS A N   1 
ATOM   2026 C CA  . HIS A 1 276 ? -22.58000 -8.99200  7.95300   1.000 39.80845  ? 276 HIS A CA  1 
ATOM   2027 C C   . HIS A 1 276 ? -22.65600 -8.45600  9.37700   1.000 39.62829  ? 276 HIS A C   1 
ATOM   2028 O O   . HIS A 1 276 ? -22.90400 -7.26400  9.58700   1.000 38.47980  ? 276 HIS A O   1 
ATOM   2029 C CB  . HIS A 1 276 ? -21.17900 -8.72800  7.35800   1.000 40.90896  ? 276 HIS A CB  1 
ATOM   2030 C CG  . HIS A 1 276 ? -20.21100 -9.85000  7.57900   1.000 39.10221  ? 276 HIS A CG  1 
ATOM   2031 N ND1 . HIS A 1 276 ? -20.47500 -11.14400 7.18600   1.000 41.13124  ? 276 HIS A ND1 1 
ATOM   2032 C CD2 . HIS A 1 276 ? -18.98900 -9.87500  8.16200   1.000 42.87470  ? 276 HIS A CD2 1 
ATOM   2033 C CE1 . HIS A 1 276 ? -19.45700 -11.91900 7.51400   1.000 41.32313  ? 276 HIS A CE1 1 
ATOM   2034 N NE2 . HIS A 1 276 ? -18.54300 -11.17400 8.11300   1.000 44.22739  ? 276 HIS A NE2 1 
ATOM   2035 N N   . LEU A 1 277 ? -22.44400 -9.33600  10.36300  1.000 42.25909  ? 277 LEU A N   1 
ATOM   2036 C CA  . LEU A 1 277 ? -22.47200 -8.88600  11.75100  1.000 44.25753  ? 277 LEU A CA  1 
ATOM   2037 C C   . LEU A 1 277 ? -21.26700 -8.02200  12.09600  1.000 43.27932  ? 277 LEU A C   1 
ATOM   2038 O O   . LEU A 1 277 ? -21.30800 -7.29000  13.09000  1.000 37.12440  ? 277 LEU A O   1 
ATOM   2039 C CB  . LEU A 1 277 ? -22.52600 -10.07200 12.72400  1.000 48.11113  ? 277 LEU A CB  1 
ATOM   2040 C CG  . LEU A 1 277 ? -23.75700 -10.98500 12.80900  1.000 54.84263  ? 277 LEU A CG  1 
ATOM   2041 C CD1 . LEU A 1 277 ? -23.52800 -12.07200 13.86900  1.000 52.69875  ? 277 LEU A CD1 1 
ATOM   2042 C CD2 . LEU A 1 277 ? -25.04300 -10.20900 13.08900  1.000 49.19379  ? 277 LEU A CD2 1 
ATOM   2043 N N   . GLU A 1 278 ? -20.20900 -8.09000  11.30700  1.000 42.26899  ? 278 GLU A N   1 
ATOM   2044 C CA  . GLU A 1 278 ? -18.97700 -7.35900  11.54200  1.000 40.44757  ? 278 GLU A CA  1 
ATOM   2045 C C   . GLU A 1 278 ? -18.62600 -6.57700  10.29300  1.000 38.56054  ? 278 GLU A C   1 
ATOM   2046 O O   . GLU A 1 278 ? -19.10100 -6.90600  9.20000   1.000 37.20549  ? 278 GLU A O   1 
ATOM   2047 C CB  . GLU A 1 278 ? -17.83600 -8.32600  11.88200  1.000 46.88451  ? 278 GLU A CB  1 
ATOM   2048 C CG  . GLU A 1 278 ? -17.56800 -8.47000  13.35700  1.000 57.13360  ? 278 GLU A CG  1 
ATOM   2049 C CD  . GLU A 1 278 ? -16.78800 -9.72900  13.66600  1.000 71.26537  ? 278 GLU A CD  1 
ATOM   2050 O OE1 . GLU A 1 278 ? -16.19500 -10.30900 12.72300  1.000 76.06332  ? 278 GLU A OE1 1 
ATOM   2051 O OE2 . GLU A 1 278 ? -16.78000 -10.14600 14.84500  1.000 80.32131  ? 278 GLU A OE2 1 
ATOM   2052 N N   . PRO A 1 279 ? -17.77900 -5.54600  10.41000  1.000 40.20157  ? 279 PRO A N   1 
ATOM   2053 C CA  . PRO A 1 279 ? -17.32700 -4.84600  9.21000   1.000 34.65933  ? 279 PRO A CA  1 
ATOM   2054 C C   . PRO A 1 279 ? -16.68500 -5.83200  8.25700   1.000 37.68685  ? 279 PRO A C   1 
ATOM   2055 O O   . PRO A 1 279 ? -16.09100 -6.83000  8.67000   1.000 42.70519  ? 279 PRO A O   1 
ATOM   2056 C CB  . PRO A 1 279 ? -16.31000 -3.83300  9.74700   1.000 36.56210  ? 279 PRO A CB  1 
ATOM   2057 C CG  . PRO A 1 279 ? -16.68100 -3.62400  11.13500  1.000 33.91933  ? 279 PRO A CG  1 
ATOM   2058 C CD  . PRO A 1 279 ? -17.16300 -4.97000  11.61700  1.000 39.88361  ? 279 PRO A CD  1 
ATOM   2059 N N   . LEU A 1 280 ? -16.83400 -5.55600  6.96800   1.000 37.03565  ? 280 LEU A N   1 
ATOM   2060 C CA  . LEU A 1 280 ? -16.33800 -6.44500  5.93300   1.000 33.31623  ? 280 LEU A CA  1 
ATOM   2061 C C   . LEU A 1 280 ? -16.26200 -5.65800  4.63700   1.000 33.66118  ? 280 LEU A C   1 
ATOM   2062 O O   . LEU A 1 280 ? -17.15600 -4.86600  4.33900   1.000 38.39719  ? 280 LEU A O   1 
ATOM   2063 C CB  . LEU A 1 280 ? -17.25500 -7.65200  5.76600   1.000 35.22398  ? 280 LEU A CB  1 
ATOM   2064 C CG  . LEU A 1 280 ? -16.65500 -8.70500  4.85400   1.000 39.38315  ? 280 LEU A CG  1 
ATOM   2065 C CD1 . LEU A 1 280 ? -15.58000 -9.38400  5.64500   1.000 32.77282  ? 280 LEU A CD1 1 
ATOM   2066 C CD2 . LEU A 1 280 ? -17.71500 -9.69800  4.35200   1.000 36.41619  ? 280 LEU A CD2 1 
ATOM   2067 N N   . HIS A 1 281 ? -15.19200 -5.85800  3.88200   1.000 35.24770  ? 281 HIS A N   1 
ATOM   2068 C CA  . HIS A 1 281 ? -14.99800 -5.15000  2.62900   1.000 33.78778  ? 281 HIS A CA  1 
ATOM   2069 C C   . HIS A 1 281 ? -14.83300 -6.16800  1.51500   1.000 33.96478  ? 281 HIS A C   1 
ATOM   2070 O O   . HIS A 1 281 ? -13.99000 -7.06300  1.61400   1.000 36.22176  ? 281 HIS A O   1 
ATOM   2071 C CB  . HIS A 1 281 ? -13.78400 -4.22000  2.68200   1.000 28.88079  ? 281 HIS A CB  1 
ATOM   2072 C CG  . HIS A 1 281 ? -13.45900 -3.60500  1.35800   1.000 29.72078  ? 281 HIS A CG  1 
ATOM   2073 N ND1 . HIS A 1 281 ? -12.61100 -4.20300  0.44900   1.000 33.20876  ? 281 HIS A ND1 1 
ATOM   2074 C CD2 . HIS A 1 281 ? -13.90700 -2.47100  0.76800   1.000 26.83936  ? 281 HIS A CD2 1 
ATOM   2075 C CE1 . HIS A 1 281 ? -12.53400 -3.45100  -0.63900  1.000 33.32674  ? 281 HIS A CE1 1 
ATOM   2076 N NE2 . HIS A 1 281 ? -13.31500 -2.39600  -0.47300  1.000 31.95908  ? 281 HIS A NE2 1 
ATOM   2077 N N   . ILE A 1 282 ? -15.64000 -6.02900  0.46700   1.000 31.41529  ? 282 ILE A N   1 
ATOM   2078 C CA  . ILE A 1 282 ? -15.55100 -6.83700  -0.74500  1.000 31.74839  ? 282 ILE A CA  1 
ATOM   2079 C C   . ILE A 1 282 ? -14.76100 -6.04700  -1.77100  1.000 29.17344  ? 282 ILE A C   1 
ATOM   2080 O O   . ILE A 1 282 ? -14.96600 -4.83900  -1.92700  1.000 33.33714  ? 282 ILE A O   1 
ATOM   2081 C CB  . ILE A 1 282 ? -16.95000 -7.15900  -1.30600  1.000 34.58328  ? 282 ILE A CB  1 
ATOM   2082 C CG1 . ILE A 1 282 ? -17.87000 -7.71200  -0.24300  1.000 33.50491  ? 282 ILE A CG1 1 
ATOM   2083 C CG2 . ILE A 1 282 ? -16.86500 -8.14200  -2.45300  1.000 40.01496  ? 282 ILE A CG2 1 
ATOM   2084 C CD1 . ILE A 1 282 ? -19.30500 -7.47300  -0.62300  1.000 36.80900  ? 282 ILE A CD1 1 
ATOM   2085 N N   . SER A 1 283 ? -13.87800 -6.71800  -2.49400  1.000 34.06313  ? 283 SER A N   1 
ATOM   2086 C CA  . SER A 1 283 ? -13.15700 -6.02500  -3.55100  1.000 33.38362  ? 283 SER A CA  1 
ATOM   2087 C C   . SER A 1 283 ? -14.12200 -5.55500  -4.62900  1.000 32.46864  ? 283 SER A C   1 
ATOM   2088 O O   . SER A 1 283 ? -15.23900 -6.05900  -4.77200  1.000 32.60154  ? 283 SER A O   1 
ATOM   2089 C CB  . SER A 1 283 ? -12.10900 -6.93100  -4.18900  1.000 32.79613  ? 283 SER A CB  1 
ATOM   2090 O OG  . SER A 1 283 ? -12.74900 -7.97300  -4.91100  1.000 35.10429  ? 283 SER A OG  1 
ATOM   2091 N N   . HIS A 1 284 ? -13.67000 -4.58200  -5.40900  1.000 32.42887  ? 284 HIS A N   1 
ATOM   2092 C CA  . HIS A 1 284 ? -14.46800 -4.15700  -6.55100  1.000 37.04682  ? 284 HIS A CA  1 
ATOM   2093 C C   . HIS A 1 284 ? -14.65000 -5.31500  -7.52700  1.000 40.97275  ? 284 HIS A C   1 
ATOM   2094 O O   . HIS A 1 284 ? -15.77300 -5.61300  -7.96400  1.000 31.20558  ? 284 HIS A O   1 
ATOM   2095 C CB  . HIS A 1 284 ? -13.81000 -2.95500  -7.22800  1.000 29.83320  ? 284 HIS A CB  1 
ATOM   2096 C CG  . HIS A 1 284 ? -14.47100 -2.55400  -8.50100  1.000 33.50873  ? 284 HIS A CG  1 
ATOM   2097 N ND1 . HIS A 1 284 ? -13.97200 -2.89900  -9.74000  1.000 43.39527  ? 284 HIS A ND1 1 
ATOM   2098 C CD2 . HIS A 1 284 ? -15.59900 -1.83900  -8.73100  1.000 36.46184  ? 284 HIS A CD2 1 
ATOM   2099 C CE1 . HIS A 1 284 ? -14.77100 -2.42000  -10.68000 1.000 40.35901  ? 284 HIS A CE1 1 
ATOM   2100 N NE2 . HIS A 1 284 ? -15.76300 -1.77000  -10.09300 1.000 42.82183  ? 284 HIS A NE2 1 
ATOM   2101 N N   . GLU A 1 285 ? -13.55000 -6.02000  -7.82900  1.000 41.53186  ? 285 GLU A N   1 
ATOM   2102 C CA  . GLU A 1 285 ? -13.60900 -7.11100  -8.79300  1.000 36.76661  ? 285 GLU A CA  1 
ATOM   2103 C C   . GLU A 1 285 ? -14.49000 -8.25400  -8.30700  1.000 35.45866  ? 285 GLU A C   1 
ATOM   2104 O O   . GLU A 1 285 ? -15.14100 -8.91900  -9.12500  1.000 34.85480  ? 285 GLU A O   1 
ATOM   2105 C CB  . GLU A 1 285 ? -12.20200 -7.59900  -9.10300  1.000 40.12272  ? 285 GLU A CB  1 
ATOM   2106 C CG  . GLU A 1 285 ? -11.43100 -6.63800  -10.00600 1.000 46.16802  ? 285 GLU A CG  1 
ATOM   2107 C CD  . GLU A 1 285 ? -12.16600 -6.32400  -11.31200 1.000 52.76745  ? 285 GLU A CD  1 
ATOM   2108 O OE1 . GLU A 1 285 ? -12.09600 -7.14900  -12.25400 1.000 51.77131  ? 285 GLU A OE1 1 
ATOM   2109 O OE2 . GLU A 1 285 ? -12.81300 -5.24900  -11.39600 1.000 50.35802  ? 285 GLU A OE2 1 
ATOM   2110 N N   . ARG A 1 286 ? -14.53300 -8.49700  -6.99100  1.000 35.47154  ? 286 ARG A N   1 
ATOM   2111 C CA  . ARG A 1 286 ? -15.46400 -9.49000  -6.46200  1.000 34.16682  ? 286 ARG A CA  1 
ATOM   2112 C C   . ARG A 1 286 ? -16.89600 -8.98500  -6.50800  1.000 31.91472  ? 286 ARG A C   1 
ATOM   2113 O O   . ARG A 1 286 ? -17.81700 -9.76100  -6.76900  1.000 37.43339  ? 286 ARG A O   1 
ATOM   2114 C CB  . ARG A 1 286 ? -15.09000 -9.87500  -5.03700  1.000 33.02441  ? 286 ARG A CB  1 
ATOM   2115 C CG  . ARG A 1 286 ? -16.01800 -10.92300 -4.40400  1.000 34.17618  ? 286 ARG A CG  1 
ATOM   2116 C CD  . ARG A 1 286 ? -15.45100 -11.37000 -3.06400  1.000 35.21758  ? 286 ARG A CD  1 
ATOM   2117 N NE  . ARG A 1 286 ? -14.04800 -11.77100 -3.17400  1.000 36.98636  ? 286 ARG A NE  1 
ATOM   2118 C CZ  . ARG A 1 286 ? -13.61800 -13.02100 -3.04300  1.000 38.02622  ? 286 ARG A CZ  1 
ATOM   2119 N NH1 . ARG A 1 286 ? -14.45500 -14.00500 -2.75200  1.000 34.12906  ? 286 ARG A NH1 1 
ATOM   2120 N NH2 . ARG A 1 286 ? -12.31300 -13.29000 -3.19800  1.000 26.64901  ? 286 ARG A NH2 1 
ATOM   2121 N N   . ARG A 1 287 ? -17.11100 -7.69100  -6.24300  1.000 36.88680  ? 287 ARG A N   1 
ATOM   2122 C CA  . ARG A 1 287 ? -18.44700 -7.11300  -6.39700  1.000 34.08971  ? 287 ARG A CA  1 
ATOM   2123 C C   . ARG A 1 287 ? -18.94600 -7.24100  -7.83400  1.000 35.65841  ? 287 ARG A C   1 
ATOM   2124 O O   . ARG A 1 287 ? -20.12900 -7.52000  -8.06500  1.000 36.71247  ? 287 ARG A O   1 
ATOM   2125 C CB  . ARG A 1 287 ? -18.44900 -5.63600  -5.98200  1.000 37.47674  ? 287 ARG A CB  1 
ATOM   2126 C CG  . ARG A 1 287 ? -18.26400 -5.35900  -4.49500  1.000 33.18879  ? 287 ARG A CG  1 
ATOM   2127 C CD  . ARG A 1 287 ? -18.61200 -3.91000  -4.14100  1.000 32.98052  ? 287 ARG A CD  1 
ATOM   2128 N NE  . ARG A 1 287 ? -17.85300 -2.88100  -4.84800  1.000 28.30171  ? 287 ARG A NE  1 
ATOM   2129 C CZ  . ARG A 1 287 ? -16.75100 -2.30800  -4.37400  1.000 35.17801  ? 287 ARG A CZ  1 
ATOM   2130 N NH1 . ARG A 1 287 ? -16.17500 -2.73300  -3.26200  1.000 35.00317  ? 287 ARG A NH1 1 
ATOM   2131 N NH2 . ARG A 1 287 ? -16.21600 -1.27800  -5.02900  1.000 30.93520  ? 287 ARG A NH2 1 
ATOM   2132 N N   . ARG A 1 288 ? -18.07000 -6.99500  -8.81500  1.000 31.72746  ? 288 ARG A N   1 
ATOM   2133 C CA  . ARG A 1 288 ? -18.48100 -7.16300  -10.20500 1.000 40.30595  ? 288 ARG A CA  1 
ATOM   2134 C C   . ARG A 1 288 ? -18.77700 -8.62500  -10.54500 1.000 35.37520  ? 288 ARG A C   1 
ATOM   2135 O O   . ARG A 1 288 ? -19.57800 -8.90000  -11.44900 1.000 38.62629  ? 288 ARG A O   1 
ATOM   2136 C CB  . ARG A 1 288 ? -17.41400 -6.60200  -11.14300 1.000 43.61516  ? 288 ARG A CB  1 
ATOM   2137 C CG  . ARG A 1 288 ? -17.44400 -5.09300  -11.28900 1.000 43.69697  ? 288 ARG A CG  1 
ATOM   2138 C CD  . ARG A 1 288 ? -16.95300 -4.71200  -12.66800 1.000 47.63729  ? 288 ARG A CD  1 
ATOM   2139 N NE  . ARG A 1 288 ? -15.62500 -5.25900  -12.91300 1.000 58.07146  ? 288 ARG A NE  1 
ATOM   2140 C CZ  . ARG A 1 288 ? -15.21600 -5.75800  -14.07400 1.000 62.21551  ? 288 ARG A CZ  1 
ATOM   2141 N NH1 . ARG A 1 288 ? -16.03300 -5.84500  -15.11900 1.000 55.28446  ? 288 ARG A NH1 1 
ATOM   2142 N NH2 . ARG A 1 288 ? -13.95700 -6.18100  -14.18900 1.000 56.86083  ? 288 ARG A NH2 1 
ATOM   2143 N N   . ALA A 1 289 ? -18.15400 -9.57400  -9.84600  1.000 31.61321  ? 289 ALA A N   1 
ATOM   2144 C CA  . ALA A 1 289 ? -18.52700 -10.97400 -10.03800 1.000 32.70926  ? 289 ALA A CA  1 
ATOM   2145 C C   . ALA A 1 289 ? -19.95300 -11.22500 -9.56100  1.000 36.03158  ? 289 ALA A C   1 
ATOM   2146 O O   . ALA A 1 289 ? -20.75300 -11.86900 -10.25200 1.000 35.34749  ? 289 ALA A O   1 
ATOM   2147 C CB  . ALA A 1 289 ? -17.53900 -11.89000 -9.31100  1.000 30.16339  ? 289 ALA A CB  1 
ATOM   2148 N N   . CYS A 1 290 ? -20.29500 -10.71400 -8.37800  1.000 31.37951  ? 290 CYS A N   1 
ATOM   2149 C CA  . CYS A 1 290 ? -21.66700 -10.83100 -7.90100  1.000 33.22650  ? 290 CYS A CA  1 
ATOM   2150 C C   . CYS A 1 290 ? -22.65500 -10.17400 -8.84200  1.000 35.57055  ? 290 CYS A C   1 
ATOM   2151 O O   . CYS A 1 290 ? -23.81100 -10.60000 -8.92100  1.000 38.23041  ? 290 CYS A O   1 
ATOM   2152 C CB  . CYS A 1 290 ? -21.79200 -10.20700 -6.52800  1.000 32.67335  ? 290 CYS A CB  1 
ATOM   2153 S SG  . CYS A 1 290 ? -20.88700 -11.13000 -5.35300  1.000 36.33585  ? 290 CYS A SG  1 
ATOM   2154 N N   . GLU A 1 291 ? -22.23900 -9.12000  -9.53800  1.000 37.10609  ? 291 GLU A N   1 
ATOM   2155 C CA  . GLU A 1 291 ? -23.15100 -8.47000  -10.47000 1.000 36.49233  ? 291 GLU A CA  1 
ATOM   2156 C C   . GLU A 1 291 ? -23.50500 -9.40000  -11.61700 1.000 36.10802  ? 291 GLU A C   1 
ATOM   2157 O O   . GLU A 1 291 ? -24.65900 -9.44800  -12.04200 1.000 37.31125  ? 291 GLU A O   1 
ATOM   2158 C CB  . GLU A 1 291 ? -22.54300 -7.18200  -10.99700 1.000 33.42749  ? 291 GLU A CB  1 
ATOM   2159 C CG  . GLU A 1 291 ? -23.54000 -6.37800  -11.78900 1.000 41.69936  ? 291 GLU A CG  1 
ATOM   2160 C CD  . GLU A 1 291 ? -23.00500 -5.03700  -12.15400 1.000 37.66460  ? 291 GLU A CD  1 
ATOM   2161 O OE1 . GLU A 1 291 ? -21.76400 -4.90000  -12.20000 1.000 42.17703  ? 291 GLU A OE1 1 
ATOM   2162 O OE2 . GLU A 1 291 ? -23.81700 -4.12000  -12.38700 1.000 48.17224  ? 291 GLU A OE2 1 
ATOM   2163 N N   . VAL A 1 292 ? -22.52500 -10.16100 -12.10600 1.000 40.24556  ? 292 VAL A N   1 
ATOM   2164 C CA  . VAL A 1 292 ? -22.78800 -11.21400 -13.08200 1.000 40.61141  ? 292 VAL A CA  1 
ATOM   2165 C C   . VAL A 1 292 ? -23.89000 -12.14400 -12.58700 1.000 39.47172  ? 292 VAL A C   1 
ATOM   2166 O O   . VAL A 1 292 ? -24.81900 -12.47700 -13.33200 1.000 38.60371  ? 292 VAL A O   1 
ATOM   2167 C CB  . VAL A 1 292 ? -21.49100 -11.98700 -13.39200 1.000 38.94464  ? 292 VAL A CB  1 
ATOM   2168 C CG1 . VAL A 1 292 ? -21.80300 -13.34600 -13.97100 1.000 40.82855  ? 292 VAL A CG1 1 
ATOM   2169 C CG2 . VAL A 1 292 ? -20.61800 -11.20300 -14.35300 1.000 41.90928  ? 292 VAL A CG2 1 
ATOM   2170 N N   . LEU A 1 293 ? -23.82100 -12.56400 -11.31700 1.000 35.19625  ? 293 LEU A N   1 
ATOM   2171 C CA  . LEU A 1 293 ? -24.84500 -13.46700 -10.79400 1.000 35.17895  ? 293 LEU A CA  1 
ATOM   2172 C C   . LEU A 1 293 ? -26.24400 -12.85500 -10.88100 1.000 39.47851  ? 293 LEU A C   1 
ATOM   2173 O O   . LEU A 1 293 ? -27.20200 -13.54400 -11.24600 1.000 38.57819  ? 293 LEU A O   1 
ATOM   2174 C CB  . LEU A 1 293 ? -24.52100 -13.86000 -9.35300  1.000 34.13973  ? 293 LEU A CB  1 
ATOM   2175 C CG  . LEU A 1 293 ? -23.18100 -14.56500 -9.13700  1.000 36.18845  ? 293 LEU A CG  1 
ATOM   2176 C CD1 . LEU A 1 293 ? -23.07700 -15.05400 -7.70200  1.000 35.81404  ? 293 LEU A CD1 1 
ATOM   2177 C CD2 . LEU A 1 293 ? -22.99600 -15.71900 -10.11600 1.000 30.86205  ? 293 LEU A CD2 1 
ATOM   2178 N N   . THR A 1 294 ? -26.38300 -11.55800 -10.56800 1.000 38.76560  ? 294 THR A N   1 
ATOM   2179 C CA  . THR A 1 294 ? -27.71600 -10.95200 -10.53500 1.000 38.67860  ? 294 THR A CA  1 
ATOM   2180 C C   . THR A 1 294 ? -28.31000 -10.82300 -11.93100 1.000 39.82589  ? 294 THR A C   1 
ATOM   2181 O O   . THR A 1 294 ? -29.50500 -11.06400 -12.13000 1.000 43.85435  ? 294 THR A O   1 
ATOM   2182 C CB  . THR A 1 294 ? -27.66900 -9.58000  -9.86500  1.000 41.58566  ? 294 THR A CB  1 
ATOM   2183 O OG1 . THR A 1 294 ? -26.93000 -8.67200  -10.69600 1.000 47.51185  ? 294 THR A OG1 1 
ATOM   2184 C CG2 . THR A 1 294 ? -27.01600 -9.66400  -8.50000  1.000 40.06474  ? 294 THR A CG2 1 
ATOM   2185 N N   . GLN A 1 295 ? -27.50500 -10.42800 -12.91100 1.000 39.36208  ? 295 GLN A N   1 
ATOM   2186 C CA  . GLN A 1 295 ? -28.00500 -10.41500 -14.28000 1.000 42.65761  ? 295 GLN A CA  1 
ATOM   2187 C C   . GLN A 1 295 ? -28.39100 -11.81700 -14.74100 1.000 45.76238  ? 295 GLN A C   1 
ATOM   2188 O O   . GLN A 1 295 ? -29.27900 -11.97600 -15.59200 1.000 46.75968  ? 295 GLN A O   1 
ATOM   2189 C CB  . GLN A 1 295 ? -26.95500 -9.81000  -15.20400 1.000 43.27916  ? 295 GLN A CB  1 
ATOM   2190 C CG  . GLN A 1 295 ? -26.31100 -8.56800  -14.62600 1.000 38.54485  ? 295 GLN A CG  1 
ATOM   2191 C CD  . GLN A 1 295 ? -25.43800 -7.86900  -15.63400 1.000 52.22088  ? 295 GLN A CD  1 
ATOM   2192 O OE1 . GLN A 1 295 ? -24.40200 -7.29500  -15.29300 1.000 49.12809  ? 295 GLN A OE1 1 
ATOM   2193 N NE2 . GLN A 1 295 ? -25.85200 -7.91100  -16.89400 1.000 60.86192  ? 295 GLN A NE2 1 
ATOM   2194 N N   . LEU A 1 296 ? -27.73500 -12.84000 -14.19300 1.000 37.00869  ? 296 LEU A N   1 
ATOM   2195 C CA  . LEU A 1 296 ? -28.14900 -14.21400 -14.43000 1.000 40.97892  ? 296 LEU A CA  1 
ATOM   2196 C C   . LEU A 1 296 ? -29.53300 -14.48400 -13.85300 1.000 42.64627  ? 296 LEU A C   1 
ATOM   2197 O O   . LEU A 1 296 ? -30.43600 -14.94300 -14.56000 1.000 39.83451  ? 296 LEU A O   1 
ATOM   2198 C CB  . LEU A 1 296 ? -27.13300 -15.17100 -13.82100 1.000 42.20353  ? 296 LEU A CB  1 
ATOM   2199 C CG  . LEU A 1 296 ? -25.90900 -15.41600 -14.67300 1.000 49.91081  ? 296 LEU A CG  1 
ATOM   2200 C CD1 . LEU A 1 296 ? -25.35700 -16.79100 -14.31100 1.000 48.91270  ? 296 LEU A CD1 1 
ATOM   2201 C CD2 . LEU A 1 296 ? -26.27800 -15.30800 -16.15200 1.000 49.31426  ? 296 LEU A CD2 1 
ATOM   2202 N N   . LEU A 1 297 ? -29.70400 -14.23200 -12.55600 1.000 40.09839  ? 297 LEU A N   1 
ATOM   2203 C CA  . LEU A 1 297 ? -30.99800 -14.44800 -11.92600 1.000 38.17935  ? 297 LEU A CA  1 
ATOM   2204 C C   . LEU A 1 297 ? -32.09600 -13.71000 -12.67000 1.000 41.39572  ? 297 LEU A C   1 
ATOM   2205 O O   . LEU A 1 297 ? -33.17500 -14.26400 -12.91400 1.000 41.25134  ? 297 LEU A O   1 
ATOM   2206 C CB  . LEU A 1 297 ? -30.95800 -13.99900 -10.46900 1.000 36.60632  ? 297 LEU A CB  1 
ATOM   2207 C CG  . LEU A 1 297 ? -32.24200 -14.31100 -9.70000  1.000 39.68669  ? 297 LEU A CG  1 
ATOM   2208 C CD1 . LEU A 1 297 ? -32.48300 -15.80800 -9.64500  1.000 38.23691  ? 297 LEU A CD1 1 
ATOM   2209 C CD2 . LEU A 1 297 ? -32.19100 -13.71800 -8.29400  1.000 39.87403  ? 297 LEU A CD2 1 
ATOM   2210 N N   . ALA A 1 298 ? -31.83800 -12.44900 -13.03700 1.000 42.51585  ? 298 ALA A N   1 
ATOM   2211 C CA  . ALA A 1 298 ? -32.84200 -11.67000 -13.75500 1.000 44.90722  ? 298 ALA A CA  1 
ATOM   2212 C C   . ALA A 1 298 ? -33.24500 -12.37600 -15.03800 1.000 39.36730  ? 298 ALA A C   1 
ATOM   2213 O O   . ALA A 1 298 ? -34.43600 -12.50600 -15.33700 1.000 37.48334  ? 298 ALA A O   1 
ATOM   2214 C CB  . ALA A 1 298 ? -32.31200 -10.26500 -14.05100 1.000 41.15301  ? 298 ALA A CB  1 
ATOM   2215 N N   . LEU A 1 299 ? -32.25500 -12.88800 -15.77200 1.000 38.01907  ? 299 LEU A N   1 
ATOM   2216 C CA  . LEU A 1 299 ? -32.48500 -13.56500 -17.04200 1.000 38.12595  ? 299 LEU A CA  1 
ATOM   2217 C C   . LEU A 1 299 ? -33.19200 -14.91100 -16.85000 1.000 42.36902  ? 299 LEU A C   1 
ATOM   2218 O O   . LEU A 1 299 ? -34.11300 -15.24700 -17.60700 1.000 43.91637  ? 299 LEU A O   1 
ATOM   2219 C CB  . LEU A 1 299 ? -31.13600 -13.72700 -17.74300 1.000 40.12084  ? 299 LEU A CB  1 
ATOM   2220 C CG  . LEU A 1 299 ? -31.01400 -14.44100 -19.08200 1.000 48.40136  ? 299 LEU A CG  1 
ATOM   2221 C CD1 . LEU A 1 299 ? -31.95400 -13.81700 -20.08800 1.000 44.21954  ? 299 LEU A CD1 1 
ATOM   2222 C CD2 . LEU A 1 299 ? -29.56900 -14.39600 -19.56700 1.000 43.85442  ? 299 LEU A CD2 1 
ATOM   2223 N N   . GLN A 1 300 ? -32.77900 -15.69000 -15.83700 1.000 42.66395  ? 300 GLN A N   1 
ATOM   2224 C CA  . GLN A 1 300 ? -33.48100 -16.92500 -15.47200 1.000 41.63507  ? 300 GLN A CA  1 
ATOM   2225 C C   . GLN A 1 300 ? -34.93400 -16.67200 -15.07600 1.000 44.34479  ? 300 GLN A C   1 
ATOM   2226 O O   . GLN A 1 300 ? -35.79800 -17.53000 -15.30900 1.000 43.84832  ? 300 GLN A O   1 
ATOM   2227 C CB  . GLN A 1 300 ? -32.77200 -17.62200 -14.30900 1.000 37.43655  ? 300 GLN A CB  1 
ATOM   2228 C CG  . GLN A 1 300 ? -31.35000 -18.02600 -14.56200 1.000 46.80933  ? 300 GLN A CG  1 
ATOM   2229 C CD  . GLN A 1 300 ? -31.24500 -19.47500 -14.94800 1.000 58.91525  ? 300 GLN A CD  1 
ATOM   2230 O OE1 . GLN A 1 300 ? -31.76100 -19.89200 -15.98600 1.000 61.45686  ? 300 GLN A OE1 1 
ATOM   2231 N NE2 . GLN A 1 300 ? -30.59900 -20.26300 -14.10400 1.000 62.82632  ? 300 GLN A NE2 1 
ATOM   2232 N N   . LEU A 1 301 ? -35.22500 -15.52600 -14.44800 1.000 39.13069  ? 301 LEU A N   1 
ATOM   2233 C CA  . LEU A 1 301 ? -36.60300 -15.25300 -14.05600 1.000 41.07928  ? 301 LEU A CA  1 
ATOM   2234 C C   . LEU A 1 301 ? -37.47400 -14.86400 -15.24100 1.000 41.61891  ? 301 LEU A C   1 
ATOM   2235 O O   . LEU A 1 301 ? -38.66100 -15.20500 -15.26000 1.000 45.22788  ? 301 LEU A O   1 
ATOM   2236 C CB  . LEU A 1 301 ? -36.65500 -14.15000 -13.00300 1.000 41.16061  ? 301 LEU A CB  1 
ATOM   2237 C CG  . LEU A 1 301 ? -36.05100 -14.43800 -11.63100 1.000 41.09236  ? 301 LEU A CG  1 
ATOM   2238 C CD1 . LEU A 1 301 ? -36.40300 -13.28300 -10.71800 1.000 39.37508  ? 301 LEU A CD1 1 
ATOM   2239 C CD2 . LEU A 1 301 ? -36.55900 -15.76000 -11.05600 1.000 45.24849  ? 301 LEU A CD2 1 
ATOM   2240 N N   . SER A 1 302 ? -36.91700 -14.15600 -16.23100 1.000 37.61209  ? 302 SER A N   1 
ATOM   2241 C CA  . SER A 1 302 ? -37.73500 -13.73800 -17.36800 1.000 47.09877  ? 302 SER A CA  1 
ATOM   2242 C C   . SER A 1 302 ? -38.15700 -14.92900 -18.21400 1.000 46.32894  ? 302 SER A C   1 
ATOM   2243 O O   . SER A 1 302 ? -39.31000 -15.00200 -18.65700 1.000 44.06791  ? 302 SER A O   1 
ATOM   2244 C CB  . SER A 1 302 ? -36.98400 -12.72500 -18.22400 1.000 43.51223  ? 302 SER A CB  1 
ATOM   2245 O OG  . SER A 1 302 ? -36.74400 -11.54900 -17.48500 1.000 51.63650  ? 302 SER A OG  1 
ATOM   2246 N N   . ALA A 1 303 ? -37.23800 -15.87500 -18.44200 1.000 44.66569  ? 303 ALA A N   1 
ATOM   2247 C CA  . ALA A 1 303 ? -37.56200 -17.04700 -19.25200 1.000 46.35708  ? 303 ALA A CA  1 
ATOM   2248 C C   . ALA A 1 303 ? -38.54800 -17.96000 -18.53200 1.000 42.91802  ? 303 ALA A C   1 
ATOM   2249 O O   . ALA A 1 303 ? -39.50100 -18.45500 -19.14200 1.000 43.58122  ? 303 ALA A O   1 
ATOM   2250 C CB  . ALA A 1 303 ? -36.28500 -17.80800 -19.60900 1.000 44.95085  ? 303 ALA A CB  1 
ATOM   2251 N N   . GLU A 1 304 ? -38.32200 -18.20700 -17.24100 1.000 46.73750  ? 304 GLU A N   1 
ATOM   2252 C CA  . GLU A 1 304 ? -39.28100 -18.96600 -16.44900 1.000 42.85561  ? 304 GLU A CA  1 
ATOM   2253 C C   . GLU A 1 304 ? -40.64000 -18.29100 -16.44200 1.000 41.37979  ? 304 GLU A C   1 
ATOM   2254 O O   . GLU A 1 304 ? -41.66900 -18.95300 -16.60800 1.000 35.43403  ? 304 GLU A O   1 
ATOM   2255 C CB  . GLU A 1 304 ? -38.76800 -19.12200 -15.02200 1.000 46.22611  ? 304 GLU A CB  1 
ATOM   2256 C CG  . GLU A 1 304 ? -37.98800 -20.38100 -14.79900 1.000 54.39410  ? 304 GLU A CG  1 
ATOM   2257 C CD  . GLU A 1 304 ? -38.86900 -21.61400 -14.88600 1.000 60.58243  ? 304 GLU A CD  1 
ATOM   2258 O OE1 . GLU A 1 304 ? -39.77000 -21.74500 -14.02300 1.000 55.95549  ? 304 GLU A OE1 1 
ATOM   2259 O OE2 . GLU A 1 304 ? -38.66800 -22.43900 -15.81700 1.000 56.09123  ? 304 GLU A OE2 1 
ATOM   2260 N N   . GLU A 1 305 ? -40.66600 -16.96900 -16.25400 1.000 43.60098  ? 305 GLU A N   1 
ATOM   2261 C CA  . GLU A 1 305 ? -41.94300 -16.28100 -16.11100 1.000 41.37100  ? 305 GLU A CA  1 
ATOM   2262 C C   . GLU A 1 305 ? -42.71600 -16.28800 -17.42100 1.000 42.25914  ? 305 GLU A C   1 
ATOM   2263 O O   . GLU A 1 305 ? -43.91000 -16.61500 -17.45100 1.000 40.59940  ? 305 GLU A O   1 
ATOM   2264 C CB  . GLU A 1 305 ? -41.73100 -14.85500 -15.61900 1.000 42.51538  ? 305 GLU A CB  1 
ATOM   2265 C CG  . GLU A 1 305 ? -42.88300 -14.36600 -14.77300 1.000 56.66552  ? 305 GLU A CG  1 
ATOM   2266 C CD  . GLU A 1 305 ? -42.81000 -12.88700 -14.47100 1.000 67.71793  ? 305 GLU A CD  1 
ATOM   2267 O OE1 . GLU A 1 305 ? -41.74100 -12.41900 -13.99800 1.000 59.26452  ? 305 GLU A OE1 1 
ATOM   2268 O OE2 . GLU A 1 305 ? -43.83200 -12.19800 -14.71600 1.000 73.18200  ? 305 GLU A OE2 1 
ATOM   2269 N N   . ARG A 1 306 ? -42.05700 -15.94400 -18.52200 1.000 39.99882  ? 306 ARG A N   1 
ATOM   2270 C CA  . ARG A 1 306 ? -42.76800 -16.02600 -19.78600 1.000 40.88003  ? 306 ARG A CA  1 
ATOM   2271 C C   . ARG A 1 306 ? -43.08300 -17.47200 -20.15400 1.000 44.88514  ? 306 ARG A C   1 
ATOM   2272 O O   . ARG A 1 306 ? -44.01600 -17.70400 -20.93700 1.000 46.94702  ? 306 ARG A O   1 
ATOM   2273 C CB  . ARG A 1 306 ? -41.97500 -15.30900 -20.88200 1.000 43.89297  ? 306 ARG A CB  1 
ATOM   2274 C CG  . ARG A 1 306 ? -41.97700 -13.79600 -20.67400 1.000 47.76620  ? 306 ARG A CG  1 
ATOM   2275 C CD  . ARG A 1 306 ? -41.37800 -13.02500 -21.83300 1.000 51.39200  ? 306 ARG A CD  1 
ATOM   2276 N NE  . ARG A 1 306 ? -39.92100 -12.96100 -21.75000 1.000 56.10747  ? 306 ARG A NE  1 
ATOM   2277 C CZ  . ARG A 1 306 ? -39.21500 -11.83800 -21.69000 1.000 58.74826  ? 306 ARG A CZ  1 
ATOM   2278 N NH1 . ARG A 1 306 ? -39.80100 -10.64800 -21.68800 1.000 61.34872  ? 306 ARG A NH1 1 
ATOM   2279 N NH2 . ARG A 1 306 ? -37.88600 -11.91100 -21.64300 1.000 55.23583  ? 306 ARG A NH2 1 
ATOM   2280 N N   . ALA A 1 307 ? -42.37900 -18.44800 -19.55600 1.000 39.89229  ? 307 ALA A N   1 
ATOM   2281 C CA  . ALA A 1 307 ? -42.75500 -19.84700 -19.74500 1.000 37.29812  ? 307 ALA A CA  1 
ATOM   2282 C C   . ALA A 1 307 ? -44.06200 -20.16300 -19.02600 1.000 38.32996  ? 307 ALA A C   1 
ATOM   2283 O O   . ALA A 1 307 ? -44.96000 -20.79400 -19.60300 1.000 37.54384  ? 307 ALA A O   1 
ATOM   2284 C CB  . ALA A 1 307 ? -41.64000 -20.77300 -19.26700 1.000 38.16224  ? 307 ALA A CB  1 
ATOM   2285 N N   . ALA A 1 308 ? -44.19100 -19.71500 -17.77500 1.000 37.54825  ? 308 ALA A N   1 
ATOM   2286 C CA  . ALA A 1 308 ? -45.40400 -19.95700 -17.00300 1.000 36.83233  ? 308 ALA A CA  1 
ATOM   2287 C C   . ALA A 1 308 ? -46.62200 -19.33800 -17.67700 1.000 35.88975  ? 308 ALA A C   1 
ATOM   2288 O O   . ALA A 1 308 ? -47.65000 -20.00100 -17.85800 1.000 33.98452  ? 308 ALA A O   1 
ATOM   2289 C CB  . ALA A 1 308 ? -45.24300 -19.40000 -15.59000 1.000 33.76204  ? 308 ALA A CB  1 
ATOM   2290 N N   . GLU A 1 309 ? -46.52200 -18.06300 -18.05200 1.000 33.60909  ? 309 GLU A N   1 
ATOM   2291 C CA  . GLU A 1 309 ? -47.66100 -17.37900 -18.65000 1.000 41.00881  ? 309 GLU A CA  1 
ATOM   2292 C C   . GLU A 1 309 ? -48.08100 -18.00300 -19.97800 1.000 38.11449  ? 309 GLU A C   1 
ATOM   2293 O O   . GLU A 1 309 ? -49.27500 -18.02300 -20.30000 1.000 43.13551  ? 309 GLU A O   1 
ATOM   2294 C CB  . GLU A 1 309 ? -47.33100 -15.89900 -18.79500 1.000 43.07503  ? 309 GLU A CB  1 
ATOM   2295 C CG  . GLU A 1 309 ? -47.71100 -15.13900 -17.52900 1.000 54.44760  ? 309 GLU A CG  1 
ATOM   2296 C CD  . GLU A 1 309 ? -47.07600 -13.76200 -17.41500 1.000 69.69637  ? 309 GLU A CD  1 
ATOM   2297 O OE1 . GLU A 1 309 ? -46.49000 -13.27000 -18.41000 1.000 68.78340  ? 309 GLU A OE1 1 
ATOM   2298 O OE2 . GLU A 1 309 ? -47.15700 -13.17900 -16.31000 1.000 75.74476  ? 309 GLU A OE2 1 
ATOM   2299 N N   . ALA A 1 310 ? -47.13400 -18.54100 -20.75100 1.000 41.99536  ? 310 ALA A N   1 
ATOM   2300 C CA  . ALA A 1 310 ? -47.51200 -19.21100 -21.99400 1.000 39.49602  ? 310 ALA A CA  1 
ATOM   2301 C C   . ALA A 1 310 ? -48.20000 -20.53500 -21.70300 1.000 36.59760  ? 310 ALA A C   1 
ATOM   2302 O O   . ALA A 1 310 ? -49.16000 -20.90800 -22.38500 1.000 41.96589  ? 310 ALA A O   1 
ATOM   2303 C CB  . ALA A 1 310 ? -46.28900 -19.42300 -22.89400 1.000 25.24267  ? 310 ALA A CB  1 
ATOM   2304 N N   . SER A 1 311 ? -47.72100 -21.26200 -20.69800 1.000 34.89426  ? 311 SER A N   1 
ATOM   2305 C CA  . SER A 1 311 ? -48.41400 -22.47600 -20.27900 1.000 37.68203  ? 311 SER A CA  1 
ATOM   2306 C C   . SER A 1 311 ? -49.82700 -22.15600 -19.81700 1.000 33.96417  ? 311 SER A C   1 
ATOM   2307 O O   . SER A 1 311 ? -50.76000 -22.92300 -20.07500 1.000 31.27917  ? 311 SER A O   1 
ATOM   2308 C CB  . SER A 1 311 ? -47.62200 -23.17500 -19.16700 1.000 37.68688  ? 311 SER A CB  1 
ATOM   2309 O OG  . SER A 1 311 ? -46.57400 -23.97400 -19.69900 1.000 36.57154  ? 311 SER A OG  1 
ATOM   2310 N N   . GLU A 1 312 ? -49.99900 -21.01800 -19.13700 1.000 36.30985  ? 312 GLU A N   1 
ATOM   2311 C CA  . GLU A 1 312 ? -51.31800 -20.62100 -18.65200 1.000 37.92261  ? 312 GLU A CA  1 
ATOM   2312 C C   . GLU A 1 312 ? -52.24700 -20.30000 -19.80900 1.000 38.17251  ? 312 GLU A C   1 
ATOM   2313 O O   . GLU A 1 312 ? -53.39200 -20.75800 -19.83800 1.000 40.47803  ? 312 GLU A O   1 
ATOM   2314 C CB  . GLU A 1 312 ? -51.22700 -19.40400 -17.72100 1.000 39.43790  ? 312 GLU A CB  1 
ATOM   2315 C CG  . GLU A 1 312 ? -51.06600 -19.70800 -16.24100 1.000 43.21014  ? 312 GLU A CG  1 
ATOM   2316 C CD  . GLU A 1 312 ? -51.94700 -20.85500 -15.77300 1.000 50.41458  ? 312 GLU A CD  1 
ATOM   2317 O OE1 . GLU A 1 312 ? -53.13600 -20.91300 -16.16100 1.000 50.07879  ? 312 GLU A OE1 1 
ATOM   2318 O OE2 . GLU A 1 312 ? -51.43500 -21.71500 -15.02600 1.000 60.84981  ? 312 GLU A OE2 1 
ATOM   2319 N N   . ASP A 1 313 ? -51.78600 -19.48000 -20.75700 1.000 39.38083  ? 313 ASP A N   1 
ATOM   2320 C CA  . ASP A 1 313 ? -52.64800 -19.14900 -21.88500 1.000 40.85124  ? 313 ASP A CA  1 
ATOM   2321 C C   . ASP A 1 313 ? -53.09100 -20.42300 -22.58400 1.000 41.44966  ? 313 ASP A C   1 
ATOM   2322 O O   . ASP A 1 313 ? -54.26900 -20.56200 -22.94200 1.000 35.17038  ? 313 ASP A O   1 
ATOM   2323 C CB  . ASP A 1 313 ? -51.94100 -18.19300 -22.85400 1.000 44.67031  ? 313 ASP A CB  1 
ATOM   2324 C CG  . ASP A 1 313 ? -51.86100 -16.74200 -22.32100 1.000 52.60082  ? 313 ASP A CG  1 
ATOM   2325 O OD1 . ASP A 1 313 ? -52.74800 -16.32000 -21.53500 1.000 47.57009  ? 313 ASP A OD1 1 
ATOM   2326 O OD2 . ASP A 1 313 ? -50.91000 -16.01400 -22.70100 1.000 51.67348  ? 313 ASP A OD2 1 
ATOM   2327 N N   . ALA A 1 314 ? -52.17000 -21.39600 -22.70200 1.000 38.75864  ? 314 ALA A N   1 
ATOM   2328 C CA  . ALA A 1 314 ? -52.47400 -22.68600 -23.32400 1.000 38.97352  ? 314 ALA A CA  1 
ATOM   2329 C C   . ALA A 1 314 ? -53.65000 -23.38300 -22.64700 1.000 37.27480  ? 314 ALA A C   1 
ATOM   2330 O O   . ALA A 1 314 ? -54.51900 -23.94300 -23.32400 1.000 40.54420  ? 314 ALA A O   1 
ATOM   2331 C CB  . ALA A 1 314 ? -51.23900 -23.58800 -23.29600 1.000 35.52780  ? 314 ALA A CB  1 
ATOM   2332 N N   A HIS A 1 315 ? -53.67900 -23.38500 -21.31100 0.480 36.76828  ? 315 HIS A N   1 
ATOM   2333 N N   B HIS A 1 315 ? -53.70900 -23.35700 -21.31700 0.520 36.73960  ? 315 HIS A N   1 
ATOM   2334 C CA  A HIS A 1 315 ? -54.81700 -23.95400 -20.59200 0.480 37.23746  ? 315 HIS A CA  1 
ATOM   2335 C CA  B HIS A 1 315 ? -54.84100 -23.98900 -20.65100 0.520 37.42613  ? 315 HIS A CA  1 
ATOM   2336 C C   A HIS A 1 315 ? -56.09500 -23.19400 -20.92000 0.480 36.89714  ? 315 HIS A C   1 
ATOM   2337 C C   B HIS A 1 315 ? -56.12300 -23.19400 -20.87100 0.520 36.86348  ? 315 HIS A C   1 
ATOM   2338 O O   A HIS A 1 315 ? -57.13100 -23.79500 -21.23500 0.480 34.85835  ? 315 HIS A O   1 
ATOM   2339 O O   B HIS A 1 315 ? -57.19700 -23.77900 -21.07200 0.520 34.84408  ? 315 HIS A O   1 
ATOM   2340 C CB  A HIS A 1 315 ? -54.54400 -23.93900 -19.08500 0.480 38.12323  ? 315 HIS A CB  1 
ATOM   2341 C CB  B HIS A 1 315 ? -54.53900 -24.17500 -19.16500 0.520 38.18923  ? 315 HIS A CB  1 
ATOM   2342 C CG  A HIS A 1 315 ? -55.67100 -24.47100 -18.25000 0.480 40.89979  ? 315 HIS A CG  1 
ATOM   2343 C CG  B HIS A 1 315 ? -53.62300 -25.32700 -18.88900 0.520 42.88635  ? 315 HIS A CG  1 
ATOM   2344 N ND1 A HIS A 1 315 ? -56.27000 -25.69000 -18.49000 0.480 42.00458  ? 315 HIS A ND1 1 
ATOM   2345 N ND1 B HIS A 1 315 ? -52.43700 -25.51200 -19.57000 0.520 46.00094  ? 315 HIS A ND1 1 
ATOM   2346 C CD2 A HIS A 1 315 ? -56.29800 -23.95200 -17.16600 0.480 41.07450  ? 315 HIS A CD2 1 
ATOM   2347 C CD2 B HIS A 1 315 ? -53.72700 -26.36500 -18.02600 0.520 42.20204  ? 315 HIS A CD2 1 
ATOM   2348 C CE1 A HIS A 1 315 ? -57.22200 -25.89400 -17.59600 0.480 40.93620  ? 315 HIS A CE1 1 
ATOM   2349 C CE1 B HIS A 1 315 ? -51.84700 -26.60900 -19.13200 0.520 47.59311  ? 315 HIS A CE1 1 
ATOM   2350 N NE2 A HIS A 1 315 ? -57.25900 -24.85500 -16.78100 0.480 39.42465  ? 315 HIS A NE2 1 
ATOM   2351 N NE2 B HIS A 1 315 ? -52.60700 -27.14500 -18.19300 0.520 46.23153  ? 315 HIS A NE2 1 
ATOM   2352 N N   . ARG A 1 316 ? -56.02800 -21.86200 -20.87200 1.000 35.97263  ? 316 ARG A N   1 
ATOM   2353 C CA  . ARG A 1 316 ? -57.20600 -21.04400 -21.13200 1.000 33.99171  ? 316 ARG A CA  1 
ATOM   2354 C C   . ARG A 1 316 ? -57.71900 -21.28800 -22.53600 1.000 37.22084  ? 316 ARG A C   1 
ATOM   2355 O O   . ARG A 1 316 ? -58.92000 -21.51100 -22.74300 1.000 39.98534  ? 316 ARG A O   1 
ATOM   2356 C CB  . ARG A 1 316 ? -56.88000 -19.57200 -20.92800 1.000 32.77542  ? 316 ARG A CB  1 
ATOM   2357 C CG  . ARG A 1 316 ? -56.39400 -19.25100 -19.54400 1.000 35.79132  ? 316 ARG A CG  1 
ATOM   2358 C CD  . ARG A 1 316 ? -57.45100 -19.59800 -18.50700 1.000 39.72898  ? 316 ARG A CD  1 
ATOM   2359 N NE  . ARG A 1 316 ? -57.34400 -18.75600 -17.31700 1.000 44.19899  ? 316 ARG A NE  1 
ATOM   2360 C CZ  . ARG A 1 316 ? -56.39200 -18.87800 -16.40400 1.000 36.72665  ? 316 ARG A CZ  1 
ATOM   2361 N NH1 . ARG A 1 316 ? -55.45200 -19.79800 -16.51100 1.000 41.91728  ? 316 ARG A NH1 1 
ATOM   2362 N NH2 . ARG A 1 316 ? -56.37800 -18.05100 -15.36300 1.000 34.04247  ? 316 ARG A NH2 1 
ATOM   2363 N N   . ALA A 1 317 ? -56.80700 -21.29800 -23.51200 1.000 34.36672  ? 317 ALA A N   1 
ATOM   2364 C CA  . ALA A 1 317 ? -57.21000 -21.47500 -24.89600 1.000 33.75207  ? 317 ALA A CA  1 
ATOM   2365 C C   . ALA A 1 317 ? -57.80700 -22.85400 -25.13100 1.000 34.90333  ? 317 ALA A C   1 
ATOM   2366 O O   . ALA A 1 317 ? -58.69600 -23.01100 -25.97600 1.000 37.28622  ? 317 ALA A O   1 
ATOM   2367 C CB  . ALA A 1 317 ? -56.01700 -21.23000 -25.81700 1.000 32.46600  ? 317 ALA A CB  1 
ATOM   2368 N N   . ALA A 1 318 ? -57.33300 -23.86400 -24.40800 1.000 35.06682  ? 318 ALA A N   1 
ATOM   2369 C CA  . ALA A 1 318 ? -57.96100 -25.17400 -24.50300 1.000 36.99306  ? 318 ALA A CA  1 
ATOM   2370 C C   . ALA A 1 318 ? -59.37600 -25.14600 -23.93000 1.000 39.07871  ? 318 ALA A C   1 
ATOM   2371 O O   . ALA A 1 318 ? -60.27900 -25.79700 -24.46800 1.000 46.44780  ? 318 ALA A O   1 
ATOM   2372 C CB  . ALA A 1 318 ? -57.09600 -26.22100 -23.80000 1.000 32.94701  ? 318 ALA A CB  1 
ATOM   2373 N N   . LEU A 1 319 ? -59.59400 -24.39200 -22.84600 1.000 37.44899  ? 319 LEU A N   1 
ATOM   2374 C CA  . LEU A 1 319 ? -60.95200 -24.21800 -22.33200 1.000 38.33613  ? 319 LEU A CA  1 
ATOM   2375 C C   . LEU A 1 319 ? -61.84300 -23.56700 -23.37900 1.000 41.46668  ? 319 LEU A C   1 
ATOM   2376 O O   . LEU A 1 319 ? -62.90200 -24.09900 -23.72400 1.000 39.67710  ? 319 LEU A O   1 
ATOM   2377 C CB  . LEU A 1 319 ? -60.93300 -23.37200 -21.06100 1.000 40.40913  ? 319 LEU A CB  1 
ATOM   2378 C CG  . LEU A 1 319 ? -60.33100 -24.01800 -19.82100 1.000 41.38170  ? 319 LEU A CG  1 
ATOM   2379 C CD1 . LEU A 1 319 ? -60.59900 -23.17300 -18.58600 1.000 33.49063  ? 319 LEU A CD1 1 
ATOM   2380 C CD2 . LEU A 1 319 ? -60.91000 -25.40700 -19.66300 1.000 43.13834  ? 319 LEU A CD2 1 
ATOM   2381 N N   . LEU A 1 320 ? -61.40400 -22.40800 -23.89700 1.000 42.36578  ? 320 LEU A N   1 
ATOM   2382 C CA  . LEU A 1 320 ? -62.07600 -21.70800 -24.99500 1.000 39.58032  ? 320 LEU A CA  1 
ATOM   2383 C C   . LEU A 1 320 ? -62.32400 -22.60400 -26.19300 1.000 40.91389  ? 320 LEU A C   1 
ATOM   2384 O O   . LEU A 1 320 ? -63.39300 -22.54000 -26.81300 1.000 43.63513  ? 320 LEU A O   1 
ATOM   2385 C CB  . LEU A 1 320 ? -61.24100 -20.50800 -25.43500 1.000 35.41527  ? 320 LEU A CB  1 
ATOM   2386 C CG  . LEU A 1 320 ? -61.41600 -19.31000 -24.52100 1.000 39.62917  ? 320 LEU A CG  1 
ATOM   2387 C CD1 . LEU A 1 320 ? -60.43900 -18.21600 -24.88200 1.000 34.86230  ? 320 LEU A CD1 1 
ATOM   2388 C CD2 . LEU A 1 320 ? -62.85800 -18.85200 -24.64900 1.000 35.18860  ? 320 LEU A CD2 1 
ATOM   2389 N N   . GLY A 1 321 ? -61.33200 -23.41600 -26.56300 1.000 41.08476  ? 321 GLY A N   1 
ATOM   2390 C CA  . GLY A 1 321 ? -61.52000 -24.32700 -27.67000 1.000 44.77786  ? 321 GLY A CA  1 
ATOM   2391 C C   . GLY A 1 321 ? -62.62400 -25.32700 -27.41000 1.000 46.52476  ? 321 GLY A C   1 
ATOM   2392 O O   . GLY A 1 321 ? -63.36000 -25.70200 -28.33000 1.000 48.11794  ? 321 GLY A O   1 
ATOM   2393 N N   . GLN A 1 322 ? -62.77400 -25.75600 -26.15700 1.000 45.04811  ? 322 GLN A N   1 
ATOM   2394 C CA  . GLN A 1 322 ? -63.83800 -26.70000 -25.82800 1.000 46.45186  ? 322 GLN A CA  1 
ATOM   2395 C C   . GLN A 1 322 ? -65.18900 -26.01500 -25.60200 1.000 48.85673  ? 322 GLN A C   1 
ATOM   2396 O O   . GLN A 1 322 ? -66.23400 -26.65100 -25.78200 1.000 48.25727  ? 322 GLN A O   1 
ATOM   2397 C CB  . GLN A 1 322 ? -63.42400 -27.52400 -24.61300 1.000 44.20075  ? 322 GLN A CB  1 
ATOM   2398 C CG  . GLN A 1 322 ? -62.26000 -28.46400 -24.92700 1.000 52.35804  ? 322 GLN A CG  1 
ATOM   2399 C CD  . GLN A 1 322 ? -61.47600 -28.89700 -23.68600 1.000 59.53482  ? 322 GLN A CD  1 
ATOM   2400 O OE1 . GLN A 1 322 ? -61.85600 -28.58300 -22.54800 1.000 51.70081  ? 322 GLN A OE1 1 
ATOM   2401 N NE2 . GLN A 1 322 ? -60.36700 -29.61500 -23.90600 1.000 56.41105  ? 322 GLN A NE2 1 
ATOM   2402 N N   . LEU A 1 323 ? -65.20700 -24.73500 -25.22600 1.000 45.45508  ? 323 LEU A N   1 
ATOM   2403 C CA  . LEU A 1 323 ? -66.47000 -24.00800 -25.23200 1.000 45.18096  ? 323 LEU A CA  1 
ATOM   2404 C C   . LEU A 1 323 ? -67.02400 -23.88600 -26.64600 1.000 51.11378  ? 323 LEU A C   1 
ATOM   2405 O O   . LEU A 1 323 ? -68.23100 -24.03400 -26.86100 1.000 50.70572  ? 323 LEU A O   1 
ATOM   2406 C CB  . LEU A 1 323 ? -66.29900 -22.62600 -24.60500 1.000 43.36434  ? 323 LEU A CB  1 
ATOM   2407 C CG  . LEU A 1 323 ? -66.26200 -22.63300 -23.07300 1.000 52.33587  ? 323 LEU A CG  1 
ATOM   2408 C CD1 . LEU A 1 323 ? -66.14500 -21.24200 -22.53200 1.000 48.60329  ? 323 LEU A CD1 1 
ATOM   2409 C CD2 . LEU A 1 323 ? -67.50200 -23.27600 -22.52000 1.000 44.61460  ? 323 LEU A CD2 1 
ATOM   2410 N N   . ALA A 1 324 ? -66.15600 -23.62500 -27.62700 1.000 51.57790  ? 324 ALA A N   1 
ATOM   2411 C CA  . ALA A 1 324 ? -66.63100 -23.39500 -28.98700 1.000 52.83334  ? 324 ALA A CA  1 
ATOM   2412 C C   . ALA A 1 324 ? -67.27200 -24.65100 -29.57100 1.000 53.21611  ? 324 ALA A C   1 
ATOM   2413 O O   . ALA A 1 324 ? -68.23200 -24.56600 -30.34400 1.000 49.92442  ? 324 ALA A O   1 
ATOM   2414 C CB  . ALA A 1 324 ? -65.48200 -22.90800 -29.87200 1.000 47.51623  ? 324 ALA A CB  1 
ATOM   2415 N N   . THR A 1 325 ? -66.76200 -25.82600 -29.21000 1.000 53.73070  ? 325 THR A N   1 
ATOM   2416 C CA  . THR A 1 325 ? -67.36400 -27.05800 -29.70800 1.000 55.27109  ? 325 THR A CA  1 
ATOM   2417 C C   . THR A 1 325 ? -68.71700 -27.31700 -29.05900 1.000 59.28109  ? 325 THR A C   1 
ATOM   2418 O O   . THR A 1 325 ? -69.61500 -27.87800 -29.69700 1.000 64.06168  ? 325 THR A O   1 
ATOM   2419 C CB  . THR A 1 325 ? -66.42100 -28.23700 -29.46900 1.000 46.06142  ? 325 THR A CB  1 
ATOM   2420 O OG1 . THR A 1 325 ? -65.18500 -28.00200 -30.15600 1.000 46.53122  ? 325 THR A OG1 1 
ATOM   2421 C CG2 . THR A 1 325 ? -67.04100 -29.52900 -29.97100 1.000 42.86498  ? 325 THR A CG2 1 
ATOM   2422 N N   . ALA A 1 326 ? -68.88300 -26.91900 -27.80000 1.000 56.93027  ? 326 ALA A N   1 
ATOM   2423 C CA  . ALA A 1 326 ? -70.17100 -27.08500 -27.14300 1.000 52.75070  ? 326 ALA A CA  1 
ATOM   2424 C C   . ALA A 1 326 ? -71.22800 -26.21200 -27.80500 1.000 59.29671  ? 326 ALA A C   1 
ATOM   2425 O O   . ALA A 1 326 ? -72.36100 -26.65200 -28.02900 1.000 63.47127  ? 326 ALA A O   1 
ATOM   2426 C CB  . ALA A 1 326 ? -70.03100 -26.76100 -25.65900 1.000 55.15689  ? 326 ALA A CB  1 
ATOM   2427 N N   . MET A 1 327 ? -70.87300 -24.97400 -28.13800 1.000 58.00417  ? 327 MET A N   1 
ATOM   2428 C CA  . MET A 1 327 ? -71.66700 -24.19800 -29.08000 1.000 61.84146  ? 327 MET A CA  1 
ATOM   2429 C C   . MET A 1 327 ? -71.53300 -24.82100 -30.46200 1.000 66.18882  ? 327 MET A C   1 
ATOM   2430 O O   . MET A 1 327 ? -70.86300 -25.84400 -30.61700 1.000 68.57867  ? 327 MET A O   1 
ATOM   2431 C CB  . MET A 1 327 ? -71.21700 -22.74200 -29.09800 1.000 55.96493  ? 327 MET A CB  1 
ATOM   2432 C CG  . MET A 1 327 ? -71.21700 -22.10700 -27.74600 1.000 53.29253  ? 327 MET A CG  1 
ATOM   2433 S SD  . MET A 1 327 ? -70.27500 -20.58400 -27.73600 1.000 57.80297  ? 327 MET A SD  1 
ATOM   2434 C CE  . MET A 1 327 ? -69.28700 -20.85700 -26.26100 1.000 59.22874  ? 327 MET A CE  1 
ATOM   2435 N N   . GLY A 1 328 ? -72.15400 -24.23000 -31.47800 1.000 71.64365  ? 328 GLY A N   1 
ATOM   2436 C CA  . GLY A 1 328 ? -72.11400 -24.84200 -32.79600 1.000 78.26793  ? 328 GLY A CA  1 
ATOM   2437 C C   . GLY A 1 328 ? -72.58100 -26.28500 -32.74900 1.000 82.07525  ? 328 GLY A C   1 
ATOM   2438 O O   . GLY A 1 328 ? -72.27600 -27.08700 -33.63700 1.000 88.15308  ? 328 GLY A O   1 
ATOM   2439 N N   . GLU A 1 329 ? -73.29800 -26.62400 -31.68500 1.000 78.75953  ? 329 GLU A N   1 
ATOM   2440 C CA  . GLU A 1 329 ? -73.89700 -27.93800 -31.51700 1.000 80.52774  ? 329 GLU A CA  1 
ATOM   2441 C C   . GLU A 1 329 ? -75.29500 -27.73000 -30.94800 1.000 79.93565  ? 329 GLU A C   1 
ATOM   2442 O O   . GLU A 1 329 ? -75.87600 -26.64300 -31.05500 1.000 80.11231  ? 329 GLU A O   1 
ATOM   2443 C CB  . GLU A 1 329 ? -73.01300 -28.83400 -30.64100 1.000 69.96297  ? 329 GLU A CB  1 
ATOM   2444 C CG  . GLU A 1 329 ? -72.03900 -29.65200 -31.44300 1.000 74.45807  ? 329 GLU A CG  1 
ATOM   2445 C CD  . GLU A 1 329 ? -71.31700 -30.67500 -30.60200 1.000 78.89657  ? 329 GLU A CD  1 
ATOM   2446 O OE1 . GLU A 1 329 ? -71.86300 -31.07800 -29.54800 1.000 81.11679  ? 329 GLU A OE1 1 
ATOM   2447 O OE2 . GLU A 1 329 ? -70.19700 -31.07000 -30.99200 1.000 78.33799  ? 329 GLU A OE2 1 
ATOM   2448 N N   . GLY A 1 330 ? -75.83600 -28.77300 -30.32900 1.000 78.06642  ? 330 GLY A N   1 
ATOM   2449 C CA  . GLY A 1 330 ? -77.20900 -28.75600 -29.87100 1.000 87.99967  ? 330 GLY A CA  1 
ATOM   2450 C C   . GLY A 1 330 ? -77.61100 -27.58800 -28.98900 1.000 85.32057  ? 330 GLY A C   1 
ATOM   2451 O O   . GLY A 1 330 ? -76.84600 -27.15200 -28.11900 1.000 79.18572  ? 330 GLY A O   1 
ATOM   2452 N N   . GLY A 1 331 ? -78.79700 -27.04900 -29.24800 1.000 81.64859  ? 331 GLY A N   1 
ATOM   2453 C CA  . GLY A 1 331 ? -79.53300 -26.28500 -28.25900 1.000 84.14469  ? 331 GLY A CA  1 
ATOM   2454 C C   . GLY A 1 331 ? -79.35700 -24.78000 -28.31600 1.000 75.79178  ? 331 GLY A C   1 
ATOM   2455 O O   . GLY A 1 331 ? -78.97200 -24.18200 -29.32500 1.000 72.59454  ? 331 GLY A O   1 
ATOM   2456 N N   . THR A 1 332 ? -79.67500 -24.16200 -27.18400 1.000 72.26056  ? 332 THR A N   1 
ATOM   2457 C CA  . THR A 1 332 ? -79.66800 -22.72200 -27.00200 1.000 75.35622  ? 332 THR A CA  1 
ATOM   2458 C C   . THR A 1 332 ? -78.43600 -22.31900 -26.20100 1.000 72.57497  ? 332 THR A C   1 
ATOM   2459 O O   . THR A 1 332 ? -77.62000 -23.15400 -25.80500 1.000 72.34144  ? 332 THR A O   1 
ATOM   2460 C CB  . THR A 1 332 ? -80.96000 -22.26300 -26.31100 1.000 80.00425  ? 332 THR A CB  1 
ATOM   2461 O OG1 . THR A 1 332 ? -81.17600 -20.86300 -26.54600 1.000 83.48265  ? 332 THR A OG1 1 
ATOM   2462 C CG2 . THR A 1 332 ? -80.90000 -22.51100 -24.81000 1.000 71.85004  ? 332 THR A CG2 1 
ATOM   2463 N N   . LEU A 1 333 ? -78.30600 -21.01200 -25.97800 1.000 73.75728  ? 333 LEU A N   1 
ATOM   2464 C CA  . LEU A 1 333 ? -77.24000 -20.44500 -25.16200 1.000 72.17824  ? 333 LEU A CA  1 
ATOM   2465 C C   . LEU A 1 333 ? -77.22800 -21.05600 -23.76400 1.000 72.94443  ? 333 LEU A C   1 
ATOM   2466 O O   . LEU A 1 333 ? -76.37800 -21.89900 -23.45200 1.000 72.47651  ? 333 LEU A O   1 
ATOM   2467 C CB  . LEU A 1 333 ? -77.41400 -18.92600 -25.08500 1.000 75.29595  ? 333 LEU A CB  1 
ATOM   2468 C CG  . LEU A 1 333 ? -76.26300 -18.03500 -24.60600 1.000 70.24051  ? 333 LEU A CG  1 
ATOM   2469 C CD1 . LEU A 1 333 ? -76.12200 -18.05000 -23.09600 1.000 70.24351  ? 333 LEU A CD1 1 
ATOM   2470 C CD2 . LEU A 1 333 ? -74.96000 -18.43300 -25.27300 1.000 67.61812  ? 333 LEU A CD2 1 
ATOM   2471 N N   . GLU A 1 334 ? -78.17900 -20.63500 -22.92400 1.000 69.62368  ? 334 GLU A N   1 
ATOM   2472 C CA  . GLU A 1 334 ? -78.24900 -21.10200 -21.54500 1.000 69.29248  ? 334 GLU A CA  1 
ATOM   2473 C C   . GLU A 1 334 ? -78.19500 -22.62000 -21.44800 1.000 71.08404  ? 334 GLU A C   1 
ATOM   2474 O O   . GLU A 1 334 ? -77.76100 -23.16100 -20.42500 1.000 74.71324  ? 334 GLU A O   1 
ATOM   2475 C CB  . GLU A 1 334 ? -79.52700 -20.58000 -20.89300 1.000 76.93528  ? 334 GLU A CB  1 
ATOM   2476 C CG  . GLU A 1 334 ? -80.78500 -20.76700 -21.73100 1.000 77.43197  ? 334 GLU A CG  1 
ATOM   2477 C CD  . GLU A 1 334 ? -81.10100 -19.56900 -22.60800 1.000 82.25670  ? 334 GLU A CD  1 
ATOM   2478 O OE1 . GLU A 1 334 ? -80.53400 -18.48000 -22.36700 1.000 79.87662  ? 334 GLU A OE1 1 
ATOM   2479 O OE2 . GLU A 1 334 ? -81.92500 -19.71800 -23.53800 1.000 86.96850  ? 334 GLU A OE2 1 
ATOM   2480 N N   . GLU A 1 335 ? -78.63300 -23.31700 -22.49800 1.000 70.57620  ? 335 GLU A N   1 
ATOM   2481 C CA  . GLU A 1 335 ? -78.53200 -24.77200 -22.54400 1.000 69.44253  ? 335 GLU A CA  1 
ATOM   2482 C C   . GLU A 1 335 ? -77.08600 -25.23000 -22.39100 1.000 67.03601  ? 335 GLU A C   1 
ATOM   2483 O O   . GLU A 1 335 ? -76.74800 -25.97900 -21.46600 1.000 62.34786  ? 335 GLU A O   1 
ATOM   2484 C CB  . GLU A 1 335 ? -79.11700 -25.27500 -23.85900 1.000 68.07631  ? 335 GLU A CB  1 
ATOM   2485 C CG  . GLU A 1 335 ? -79.68500 -26.66500 -23.82000 1.000 75.73371  ? 335 GLU A CG  1 
ATOM   2486 C CD  . GLU A 1 335 ? -80.82900 -26.81300 -24.79800 1.000 81.80372  ? 335 GLU A CD  1 
ATOM   2487 O OE1 . GLU A 1 335 ? -81.05900 -25.86200 -25.57600 1.000 76.26382  ? 335 GLU A OE1 1 
ATOM   2488 O OE2 . GLU A 1 335 ? -81.50200 -27.86800 -24.78000 1.000 90.77962  ? 335 GLU A OE2 1 
ATOM   2489 N N   . VAL A 1 336 ? -76.21400 -24.79100 -23.30300 1.000 72.38413  ? 336 VAL A N   1 
ATOM   2490 C CA  . VAL A 1 336 ? -74.81700 -25.21300 -23.22700 1.000 72.09261  ? 336 VAL A CA  1 
ATOM   2491 C C   . VAL A 1 336 ? -74.08800 -24.48100 -22.10300 1.000 69.08936  ? 336 VAL A C   1 
ATOM   2492 O O   . VAL A 1 336 ? -73.10900 -25.00200 -21.55400 1.000 69.57975  ? 336 VAL A O   1 
ATOM   2493 C CB  . VAL A 1 336 ? -74.09900 -25.01900 -24.57700 1.000 66.93908  ? 336 VAL A CB  1 
ATOM   2494 C CG1 . VAL A 1 336 ? -75.09100 -25.06100 -25.74300 1.000 66.13995  ? 336 VAL A CG1 1 
ATOM   2495 C CG2 . VAL A 1 336 ? -73.27500 -23.74900 -24.58100 1.000 57.95891  ? 336 VAL A CG2 1 
ATOM   2496 N N   . LEU A 1 337 ? -74.56400 -23.29500 -21.71600 1.000 67.87212  ? 337 LEU A N   1 
ATOM   2497 C CA  . LEU A 1 337 ? -73.99200 -22.54700 -20.60000 1.000 70.90936  ? 337 LEU A CA  1 
ATOM   2498 C C   . LEU A 1 337 ? -74.39800 -23.17000 -19.26900 1.000 66.23185  ? 337 LEU A C   1 
ATOM   2499 O O   . LEU A 1 337 ? -74.45700 -22.48600 -18.24500 1.000 71.96631  ? 337 LEU A O   1 
ATOM   2500 C CB  . LEU A 1 337 ? -74.42400 -21.07900 -20.65600 1.000 70.96327  ? 337 LEU A CB  1 
ATOM   2501 C CG  . LEU A 1 337 ? -73.62400 -20.10700 -21.52800 1.000 68.70987  ? 337 LEU A CG  1 
ATOM   2502 C CD1 . LEU A 1 337 ? -72.28700 -19.78600 -20.88900 1.000 66.02863  ? 337 LEU A CD1 1 
ATOM   2503 C CD2 . LEU A 1 337 ? -73.43700 -20.65800 -22.92700 1.000 66.07049  ? 337 LEU A CD2 1 
ATOM   2504 N N   . GLU A 1 338 ? -74.67800 -24.46600 -19.27100 1.000 67.91707  ? 338 GLU A N   1 
ATOM   2505 C CA  . GLU A 1 338 ? -75.12700 -25.14200 -18.06800 1.000 69.44450  ? 338 GLU A CA  1 
ATOM   2506 C C   . GLU A 1 338 ? -74.36300 -26.44900 -17.91100 1.000 67.05169  ? 338 GLU A C   1 
ATOM   2507 O O   . GLU A 1 338 ? -74.01100 -26.83500 -16.79100 1.000 71.41216  ? 338 GLU A O   1 
ATOM   2508 C CB  . GLU A 1 338 ? -76.63600 -25.36500 -18.12000 1.000 76.78314  ? 338 GLU A CB  1 
ATOM   2509 C CG  . GLU A 1 338 ? -77.27700 -25.59100 -16.75400 1.000 84.11908  ? 338 GLU A CG  1 
ATOM   2510 C CD  . GLU A 1 338 ? -78.67100 -24.97600 -16.65000 1.000 89.17918  ? 338 GLU A CD  1 
ATOM   2511 O OE1 . GLU A 1 338 ? -78.86200 -23.84700 -17.17100 1.000 85.98985  ? 338 GLU A OE1 1 
ATOM   2512 O OE2 . GLU A 1 338 ? -79.56900 -25.62300 -16.05100 1.000 71.63702  ? 338 GLU A OE2 1 
ATOM   2513 N N   . LYS A 1 339 ? -74.07200 -27.13300 -19.02000 1.000 63.86085  ? 339 LYS A N   1 
ATOM   2514 C CA  . LYS A 1 339 ? -73.10900 -28.22300 -18.92900 1.000 62.88720  ? 339 LYS A CA  1 
ATOM   2515 C C   . LYS A 1 339 ? -71.70300 -27.67100 -18.77000 1.000 63.45306  ? 339 LYS A C   1 
ATOM   2516 O O   . LYS A 1 339 ? -70.93600 -28.13300 -17.91400 1.000 69.31712  ? 339 LYS A O   1 
ATOM   2517 C CB  . LYS A 1 339 ? -73.20300 -29.13900 -20.14900 1.000 64.54744  ? 339 LYS A CB  1 
ATOM   2518 C CG  . LYS A 1 339 ? -71.93300 -30.01300 -20.47200 1.000 74.04939  ? 339 LYS A CG  1 
ATOM   2519 C CD  . LYS A 1 339 ? -71.20600 -30.74300 -19.28600 1.000 71.95907  ? 339 LYS A CD  1 
ATOM   2520 C CE  . LYS A 1 339 ? -72.12500 -31.45700 -18.28600 1.000 78.38317  ? 339 LYS A CE  1 
ATOM   2521 N NZ  . LYS A 1 339 ? -71.42200 -31.73000 -16.99500 1.000 79.70131  ? 339 LYS A NZ  1 
ATOM   2522 N N   . GLU A 1 340 ? -71.35500 -26.66400 -19.56800 1.000 56.97172  ? 340 GLU A N   1 
ATOM   2523 C CA  . GLU A 1 340 ? -70.01400 -26.09300 -19.55200 1.000 59.80790  ? 340 GLU A CA  1 
ATOM   2524 C C   . GLU A 1 340 ? -69.79800 -25.07800 -18.42600 1.000 53.83851  ? 340 GLU A C   1 
ATOM   2525 O O   . GLU A 1 340 ? -68.82800 -24.31200 -18.48000 1.000 51.22669  ? 340 GLU A O   1 
ATOM   2526 C CB  . GLU A 1 340 ? -69.70800 -25.45600 -20.90700 1.000 61.96740  ? 340 GLU A CB  1 
ATOM   2527 C CG  . GLU A 1 340 ? -68.93600 -26.37200 -21.83100 1.000 60.94361  ? 340 GLU A CG  1 
ATOM   2528 C CD  . GLU A 1 340 ? -69.59000 -27.70400 -21.95500 1.000 56.28813  ? 340 GLU A CD  1 
ATOM   2529 O OE1 . GLU A 1 340 ? -70.57600 -27.78800 -22.70700 1.000 63.09270  ? 340 GLU A OE1 1 
ATOM   2530 O OE2 . GLU A 1 340 ? -69.13800 -28.65300 -21.28000 1.000 56.69219  ? 340 GLU A OE2 1 
ATOM   2531 N N   . SER A 1 341 ? -70.67800 -25.07100 -17.42200 1.000 53.24143  ? 341 SER A N   1 
ATOM   2532 C CA  . SER A 1 341 ? -70.53400 -24.16400 -16.29300 1.000 45.44423  ? 341 SER A CA  1 
ATOM   2533 C C   . SER A 1 341 ? -69.16100 -24.28600 -15.65100 1.000 44.12309  ? 341 SER A C   1 
ATOM   2534 O O   . SER A 1 341 ? -68.55500 -23.28100 -15.26900 1.000 42.42492  ? 341 SER A O   1 
ATOM   2535 C CB  . SER A 1 341 ? -71.61700 -24.45300 -15.25800 1.000 51.99363  ? 341 SER A CB  1 
ATOM   2536 O OG  . SER A 1 341 ? -71.39600 -25.71100 -14.64500 1.000 53.57541  ? 341 SER A OG  1 
ATOM   2537 N N   . GLU A 1 342 ? -68.66000 -25.51200 -15.50500 1.000 46.59452  ? 342 GLU A N   1 
ATOM   2538 C CA  . GLU A 1 342 ? -67.36200 -25.68900 -14.86900 1.000 43.79679  ? 342 GLU A CA  1 
ATOM   2539 C C   . GLU A 1 342 ? -66.26200 -25.04200 -15.70000 1.000 43.56366  ? 342 GLU A C   1 
ATOM   2540 O O   . GLU A 1 342 ? -65.31400 -24.46700 -15.14800 1.000 41.43226  ? 342 GLU A O   1 
ATOM   2541 C CB  . GLU A 1 342 ? -67.07800 -27.17400 -14.63900 1.000 44.51080  ? 342 GLU A CB  1 
ATOM   2542 C CG  . GLU A 1 342 ? -67.86600 -27.81700 -13.49300 1.000 58.77884  ? 342 GLU A CG  1 
ATOM   2543 C CD  . GLU A 1 342 ? -69.34300 -28.12100 -13.84500 1.000 74.59968  ? 342 GLU A CD  1 
ATOM   2544 O OE1 . GLU A 1 342 ? -69.71800 -28.03600 -15.05500 1.000 65.27245  ? 342 GLU A OE1 1 
ATOM   2545 O OE2 . GLU A 1 342 ? -70.11900 -28.45700 -12.90000 1.000 66.80256  ? 342 GLU A OE2 1 
ATOM   2546 N N   . ARG A 1 343 ? -66.39000 -25.09500 -17.02900 1.000 37.26532  ? 343 ARG A N   1 
ATOM   2547 C CA  . ARG A 1 343 ? -65.42000 -24.43100 -17.89300 1.000 40.37729  ? 343 ARG A CA  1 
ATOM   2548 C C   . ARG A 1 343 ? -65.59700 -22.92000 -17.87100 1.000 40.45678  ? 343 ARG A C   1 
ATOM   2549 O O   . ARG A 1 343 ? -64.61200 -22.17100 -17.91700 1.000 39.24087  ? 343 ARG A O   1 
ATOM   2550 C CB  . ARG A 1 343 ? -65.54100 -24.95000 -19.32400 1.000 47.23643  ? 343 ARG A CB  1 
ATOM   2551 C CG  . ARG A 1 343 ? -65.17800 -26.41000 -19.49700 1.000 53.24660  ? 343 ARG A CG  1 
ATOM   2552 C CD  . ARG A 1 343 ? -64.99800 -26.75000 -20.96900 1.000 49.19970  ? 343 ARG A CD  1 
ATOM   2553 N NE  . ARG A 1 343 ? -64.31500 -28.02700 -21.13900 1.000 54.46303  ? 343 ARG A NE  1 
ATOM   2554 C CZ  . ARG A 1 343 ? -64.91800 -29.20600 -21.08300 1.000 59.47254  ? 343 ARG A CZ  1 
ATOM   2555 N NH1 . ARG A 1 343 ? -66.22000 -29.30300 -20.86400 1.000 64.61432  ? 343 ARG A NH1 1 
ATOM   2556 N NH2 . ARG A 1 343 ? -64.19500 -30.31500 -21.23700 1.000 50.10934  ? 343 ARG A NH2 1 
ATOM   2557 N N   . VAL A 1 344 ? -66.84200 -22.44800 -17.81700 1.000 39.64535  ? 344 VAL A N   1 
ATOM   2558 C CA  . VAL A 1 344 ? -67.07700 -21.01000 -17.84000 1.000 39.33760  ? 344 VAL A CA  1 
ATOM   2559 C C   . VAL A 1 344 ? -66.46400 -20.34800 -16.61500 1.000 36.90271  ? 344 VAL A C   1 
ATOM   2560 O O   . VAL A 1 344 ? -65.82900 -19.29000 -16.71300 1.000 37.57288  ? 344 VAL A O   1 
ATOM   2561 C CB  . VAL A 1 344 ? -68.58000 -20.71200 -17.95100 1.000 42.73485  ? 344 VAL A CB  1 
ATOM   2562 C CG1 . VAL A 1 344 ? -68.80600 -19.22400 -17.88800 1.000 35.61146  ? 344 VAL A CG1 1 
ATOM   2563 C CG2 . VAL A 1 344 ? -69.12300 -21.29700 -19.25400 1.000 42.29004  ? 344 VAL A CG2 1 
ATOM   2564 N N   . LEU A 1 345 ? -66.65000 -20.94900 -15.44000 1.000 37.62815  ? 345 LEU A N   1 
ATOM   2565 C CA  . LEU A 1 345 ? -66.00200 -20.42000 -14.24800 1.000 30.48250  ? 345 LEU A CA  1 
ATOM   2566 C C   . LEU A 1 345 ? -64.49200 -20.58200 -14.34300 1.000 34.68931  ? 345 LEU A C   1 
ATOM   2567 O O   . LEU A 1 345 ? -63.73800 -19.65800 -14.01600 1.000 36.97243  ? 345 LEU A O   1 
ATOM   2568 C CB  . LEU A 1 345 ? -66.53600 -21.13600 -13.01600 1.000 33.93884  ? 345 LEU A CB  1 
ATOM   2569 C CG  . LEU A 1 345 ? -68.03900 -21.00700 -12.82100 1.000 36.60386  ? 345 LEU A CG  1 
ATOM   2570 C CD1 . LEU A 1 345 ? -68.53000 -21.84200 -11.64000 1.000 36.26732  ? 345 LEU A CD1 1 
ATOM   2571 C CD2 . LEU A 1 345 ? -68.34400 -19.55300 -12.60700 1.000 38.94565  ? 345 LEU A CD2 1 
ATOM   2572 N N   . ALA A 1 346 ? -64.04300 -21.76000 -14.78700 1.000 35.11948  ? 346 ALA A N   1 
ATOM   2573 C CA  . ALA A 1 346 ? -62.62000 -22.05300 -14.90800 1.000 30.66621  ? 346 ALA A CA  1 
ATOM   2574 C C   . ALA A 1 346 ? -61.90700 -21.07100 -15.82100 1.000 35.96409  ? 346 ALA A C   1 
ATOM   2575 O O   . ALA A 1 346 ? -60.72400 -20.78200 -15.60700 1.000 36.17079  ? 346 ALA A O   1 
ATOM   2576 C CB  . ALA A 1 346 ? -62.42300 -23.46900 -15.43600 1.000 31.87528  ? 346 ALA A CB  1 
ATOM   2577 N N   . LEU A 1 347 ? -62.60000 -20.56100 -16.85000 1.000 37.77870  ? 347 LEU A N   1 
ATOM   2578 C CA  . LEU A 1 347 ? -61.97000 -19.63300 -17.78600 1.000 36.52893  ? 347 LEU A CA  1 
ATOM   2579 C C   . LEU A 1 347 ? -61.20800 -18.53600 -17.05300 1.000 31.57344  ? 347 LEU A C   1 
ATOM   2580 O O   . LEU A 1 347 ? -60.13800 -18.11100 -17.49900 1.000 32.71769  ? 347 LEU A O   1 
ATOM   2581 C CB  . LEU A 1 347 ? -63.02400 -19.02800 -18.72700 1.000 33.52434  ? 347 LEU A CB  1 
ATOM   2582 C CG  . LEU A 1 347 ? -63.01000 -19.48600 -20.20100 1.000 43.11886  ? 347 LEU A CG  1 
ATOM   2583 C CD1 . LEU A 1 347 ? -61.62500 -19.35900 -20.86400 1.000 37.84940  ? 347 LEU A CD1 1 
ATOM   2584 C CD2 . LEU A 1 347 ? -63.48300 -20.90400 -20.35200 1.000 42.80568  ? 347 LEU A CD2 1 
ATOM   2585 N N   . THR A 1 348 ? -61.72600 -18.08400 -15.90600 1.000 36.81048  ? 348 THR A N   1 
ATOM   2586 C CA  . THR A 1 348 ? -61.14300 -16.96100 -15.17600 1.000 33.06835  ? 348 THR A CA  1 
ATOM   2587 C C   . THR A 1 348 ? -60.75900 -17.29400 -13.73800 1.000 32.26549  ? 348 THR A C   1 
ATOM   2588 O O   . THR A 1 348 ? -60.42100 -16.37600 -12.98000 1.000 31.75239  ? 348 THR A O   1 
ATOM   2589 C CB  . THR A 1 348 ? -62.10600 -15.77900 -15.16800 1.000 36.66394  ? 348 THR A CB  1 
ATOM   2590 O OG1 . THR A 1 348 ? -63.27200 -16.13900 -14.41700 1.000 34.68688  ? 348 THR A OG1 1 
ATOM   2591 C CG2 . THR A 1 348 ? -62.49500 -15.39200 -16.59100 1.000 35.96801  ? 348 THR A CG2 1 
ATOM   2592 N N   . GLY A 1 349 ? -60.78800 -18.56900 -13.34100 1.000 32.03449  ? 349 GLY A N   1 
ATOM   2593 C CA  . GLY A 1 349 ? -60.47600 -18.94300 -11.97300 1.000 28.97010  ? 349 GLY A CA  1 
ATOM   2594 C C   . GLY A 1 349 ? -61.45500 -18.38700 -10.95800 1.000 32.56257  ? 349 GLY A C   1 
ATOM   2595 O O   . GLY A 1 349 ? -61.04600 -17.76200 -9.97400  1.000 34.39090  ? 349 GLY A O   1 
ATOM   2596 N N   . ALA A 1 350 ? -62.75200 -18.61300 -11.17400 1.000 30.68829  ? 350 ALA A N   1 
ATOM   2597 C CA  . ALA A 1 350 ? -63.79300 -17.88500 -10.46700 1.000 33.38416  ? 350 ALA A CA  1 
ATOM   2598 C C   . ALA A 1 350 ? -64.85700 -18.84100 -9.94100  1.000 37.00095  ? 350 ALA A C   1 
ATOM   2599 O O   . ALA A 1 350 ? -65.06700 -19.93200 -10.48100 1.000 31.79980  ? 350 ALA A O   1 
ATOM   2600 C CB  . ALA A 1 350 ? -64.44200 -16.83300 -11.37900 1.000 31.69008  ? 350 ALA A CB  1 
ATOM   2601 N N   . ALA A 1 351 ? -65.55200 -18.39700 -8.88600  1.000 37.64607  ? 351 ALA A N   1 
ATOM   2602 C CA  . ALA A 1 351 ? -66.58700 -19.18800 -8.23100  1.000 34.57625  ? 351 ALA A CA  1 
ATOM   2603 C C   . ALA A 1 351 ? -67.98200 -18.87100 -8.73200  1.000 38.51099  ? 351 ALA A C   1 
ATOM   2604 O O   . ALA A 1 351 ? -68.94700 -19.51900 -8.30000  1.000 36.78077  ? 351 ALA A O   1 
ATOM   2605 C CB  . ALA A 1 351 ? -66.54700 -18.97900 -6.71600  1.000 32.05451  ? 351 ALA A CB  1 
ATOM   2606 N N   . GLY A 1 352 ? -68.12300 -17.89000 -9.61200  1.000 38.07528  ? 352 GLY A N   1 
ATOM   2607 C CA  . GLY A 1 352 ? -69.44400 -17.53700 -10.08700 1.000 37.64317  ? 352 GLY A CA  1 
ATOM   2608 C C   . GLY A 1 352 ? -69.36200 -16.75400 -11.37300 1.000 38.93511  ? 352 GLY A C   1 
ATOM   2609 O O   . GLY A 1 352 ? -68.33100 -16.16000 -11.70400 1.000 39.14754  ? 352 GLY A O   1 
ATOM   2610 N N   . VAL A 1 353 ? -70.45900 -16.77800 -12.11400 1.000 35.56487  ? 353 VAL A N   1 
ATOM   2611 C CA  . VAL A 1 353 ? -70.57700 -15.92000 -13.28200 1.000 39.23176  ? 353 VAL A CA  1 
ATOM   2612 C C   . VAL A 1 353 ? -72.03800 -15.53400 -13.43700 1.000 38.90435  ? 353 VAL A C   1 
ATOM   2613 O O   . VAL A 1 353 ? -72.93400 -16.36500 -13.26400 1.000 42.36291  ? 353 VAL A O   1 
ATOM   2614 C CB  . VAL A 1 353 ? -70.03300 -16.59200 -14.55800 1.000 38.91760  ? 353 VAL A CB  1 
ATOM   2615 C CG1 . VAL A 1 353 ? -70.87700 -17.79900 -14.92700 1.000 42.05707  ? 353 VAL A CG1 1 
ATOM   2616 C CG2 . VAL A 1 353 ? -69.98500 -15.59400 -15.70200 1.000 38.84872  ? 353 VAL A CG2 1 
ATOM   2617 N N   . ALA A 1 354 ? -72.26900 -14.25200 -13.69700 1.000 42.04594  ? 354 ALA A N   1 
ATOM   2618 C CA  . ALA A 1 354 ? -73.55900 -13.72500 -14.10900 1.000 43.21137  ? 354 ALA A CA  1 
ATOM   2619 C C   . ALA A 1 354 ? -73.51200 -13.37700 -15.59100 1.000 44.96986  ? 354 ALA A C   1 
ATOM   2620 O O   . ALA A 1 354 ? -72.54700 -12.76600 -16.06700 1.000 46.25891  ? 354 ALA A O   1 
ATOM   2621 C CB  . ALA A 1 354 ? -73.92200 -12.48800 -13.29000 1.000 42.60262  ? 354 ALA A CB  1 
ATOM   2622 N N   . LEU A 1 355 ? -74.55500 -13.76200 -16.32000 1.000 52.71248  ? 355 LEU A N   1 
ATOM   2623 C CA  . LEU A 1 355 ? -74.63900 -13.54000 -17.76000 1.000 53.41512  ? 355 LEU A CA  1 
ATOM   2624 C C   . LEU A 1 355 ? -75.86700 -12.69600 -18.06700 1.000 58.33574  ? 355 LEU A C   1 
ATOM   2625 O O   . LEU A 1 355 ? -76.99700 -13.12000 -17.80500 1.000 62.91337  ? 355 LEU A O   1 
ATOM   2626 C CB  . LEU A 1 355 ? -74.69100 -14.87200 -18.51300 1.000 55.94565  ? 355 LEU A CB  1 
ATOM   2627 C CG  . LEU A 1 355 ? -73.38600 -15.69100 -18.46400 1.000 56.94766  ? 355 LEU A CG  1 
ATOM   2628 C CD1 . LEU A 1 355 ? -73.60800 -17.14800 -18.87800 1.000 59.15825  ? 355 LEU A CD1 1 
ATOM   2629 C CD2 . LEU A 1 355 ? -72.28700 -15.04100 -19.31700 1.000 46.21246  ? 355 LEU A CD2 1 
ATOM   2630 N N   . LEU A 1 356 ? -75.64700 -11.50800 -18.62000 1.000 57.81434  ? 356 LEU A N   1 
ATOM   2631 C CA  . LEU A 1 356 ? -76.72700 -10.60800 -19.03100 1.000 62.17262  ? 356 LEU A CA  1 
ATOM   2632 C C   . LEU A 1 356 ? -76.79300 -10.59700 -20.55600 1.000 67.17759  ? 356 LEU A C   1 
ATOM   2633 O O   . LEU A 1 356 ? -76.15300 -9.78200  -21.22700 1.000 63.57265  ? 356 LEU A O   1 
ATOM   2634 C CB  . LEU A 1 356 ? -76.51000 -9.22100  -18.47500 1.000 54.11146  ? 356 LEU A CB  1 
ATOM   2635 C CG  . LEU A 1 356 ? -76.38000 -9.35100  -16.96800 1.000 60.87864  ? 356 LEU A CG  1 
ATOM   2636 C CD1 . LEU A 1 356 ? -74.97100 -9.01300  -16.54000 1.000 56.07377  ? 356 LEU A CD1 1 
ATOM   2637 C CD2 . LEU A 1 356 ? -77.40900 -8.47600  -16.28700 1.000 64.04585  ? 356 LEU A CD2 1 
ATOM   2638 N N   . LEU A 1 357 ? -77.58700 -11.50900 -21.10000 1.000 67.42000  ? 357 LEU A N   1 
ATOM   2639 C CA  . LEU A 1 357 ? -77.68100 -11.67400 -22.53900 1.000 70.58799  ? 357 LEU A CA  1 
ATOM   2640 C C   . LEU A 1 357 ? -79.03600 -11.25300 -23.07900 1.000 76.88227  ? 357 LEU A C   1 
ATOM   2641 O O   . LEU A 1 357 ? -79.35900 -11.56200 -24.23300 1.000 82.25854  ? 357 LEU A O   1 
ATOM   2642 C CB  . LEU A 1 357 ? -77.37000 -13.12300 -22.90800 1.000 70.96064  ? 357 LEU A CB  1 
ATOM   2643 C CG  . LEU A 1 357 ? -75.93200 -13.43700 -22.50800 1.000 63.31879  ? 357 LEU A CG  1 
ATOM   2644 C CD1 . LEU A 1 357 ? -75.50800 -14.77600 -23.01200 1.000 63.84003  ? 357 LEU A CD1 1 
ATOM   2645 C CD2 . LEU A 1 357 ? -75.04300 -12.36800 -23.06900 1.000 66.18523  ? 357 LEU A CD2 1 
ATOM   2646 N N   . GLY A 1 358 ? -79.82700 -10.54700 -22.27500 1.000 78.77714  ? 358 GLY A N   1 
ATOM   2647 C CA  . GLY A 1 358 ? -81.11600 -10.05600 -22.70600 1.000 81.26670  ? 358 GLY A CA  1 
ATOM   2648 C C   . GLY A 1 358 ? -82.12900 -9.97600  -21.58800 1.000 82.59712  ? 358 GLY A C   1 
ATOM   2649 O O   . GLY A 1 358 ? -82.41000 -8.89300  -21.06400 1.000 80.81584  ? 358 GLY A O   1 
ATOM   2650 N N   . GLU A 1 359 ? -82.68000 -11.13100 -21.21700 1.000 84.25213  ? 359 GLU A N   1 
ATOM   2651 C CA  . GLU A 1 359 ? -83.73900 -11.20800 -20.22200 1.000 83.80666  ? 359 GLU A CA  1 
ATOM   2652 C C   . GLU A 1 359 ? -83.19300 -10.93500 -18.82200 1.000 78.23826  ? 359 GLU A C   1 
ATOM   2653 O O   . GLU A 1 359 ? -82.35300 -10.05000 -18.62000 1.000 72.74533  ? 359 GLU A O   1 
ATOM   2654 C CB  . GLU A 1 359 ? -84.43600 -12.58400 -20.30400 1.000 84.19279  ? 359 GLU A CB  1 
ATOM   2655 C CG  . GLU A 1 359 ? -83.53000 -13.82800 -20.05600 1.000 90.14748  ? 359 GLU A CG  1 
ATOM   2656 C CD  . GLU A 1 359 ? -83.52800 -14.84200 -21.20300 1.000 97.58418  ? 359 GLU A CD  1 
ATOM   2657 O OE1 . GLU A 1 359 ? -83.24200 -14.43400 -22.35100 1.000 103.88941 ? 359 GLU A OE1 1 
ATOM   2658 O OE2 . GLU A 1 359 ? -83.80000 -16.04200 -20.95400 1.000 89.37349  ? 359 GLU A OE2 1 
ATOM   2659 N N   . GLU A 1 360 ? -83.69500 -11.67500 -17.84500 1.000 76.68956  ? 360 GLU A N   1 
ATOM   2660 C CA  . GLU A 1 360 ? -83.13900 -11.65400 -16.51100 1.000 74.67405  ? 360 GLU A CA  1 
ATOM   2661 C C   . GLU A 1 360 ? -81.68700 -12.14100 -16.55200 1.000 68.52556  ? 360 GLU A C   1 
ATOM   2662 O O   . GLU A 1 360 ? -81.26600 -12.80600 -17.50300 1.000 64.72518  ? 360 GLU A O   1 
ATOM   2663 C CB  . GLU A 1 360 ? -83.99300 -12.52800 -15.58500 1.000 71.50378  ? 360 GLU A CB  1 
ATOM   2664 C CG  . GLU A 1 360 ? -85.49900 -12.19500 -15.58600 1.000 73.27336  ? 360 GLU A CG  1 
ATOM   2665 C CD  . GLU A 1 360 ? -86.24200 -12.66800 -16.84700 1.000 74.63491  ? 360 GLU A CD  1 
ATOM   2666 O OE1 . GLU A 1 360 ? -85.86000 -13.72200 -17.42700 1.000 72.28373  ? 360 GLU A OE1 1 
ATOM   2667 O OE2 . GLU A 1 360 ? -87.20300 -11.96800 -17.25500 1.000 65.53111  ? 360 GLU A OE2 1 
ATOM   2668 N N   . PRO A 1 361 ? -80.89500 -11.80400 -15.53800 1.000 64.61799  ? 361 PRO A N   1 
ATOM   2669 C CA  . PRO A 1 361 ? -79.53000 -12.33600 -15.46600 1.000 61.76370  ? 361 PRO A CA  1 
ATOM   2670 C C   . PRO A 1 361 ? -79.51000 -13.86100 -15.38800 1.000 61.19517  ? 361 PRO A C   1 
ATOM   2671 O O   . PRO A 1 361 ? -80.43200 -14.49500 -14.87000 1.000 64.17107  ? 361 PRO A O   1 
ATOM   2672 C CB  . PRO A 1 361 ? -78.97900 -11.70800 -14.18200 1.000 57.82888  ? 361 PRO A CB  1 
ATOM   2673 C CG  . PRO A 1 361 ? -79.83400 -10.48800 -13.94700 1.000 59.42128  ? 361 PRO A CG  1 
ATOM   2674 C CD  . PRO A 1 361 ? -81.18500 -10.84400 -14.45800 1.000 60.17531  ? 361 PRO A CD  1 
ATOM   2675 N N   . LEU A 1 362 ? -78.43200 -14.45100 -15.90400 1.000 55.61203  ? 362 LEU A N   1 
ATOM   2676 C CA  . LEU A 1 362 ? -78.18700 -15.88500 -15.80100 1.000 55.07068  ? 362 LEU A CA  1 
ATOM   2677 C C   . LEU A 1 362 ? -77.08900 -16.08700 -14.76500 1.000 52.57046  ? 362 LEU A C   1 
ATOM   2678 O O   . LEU A 1 362 ? -75.92400 -15.75800 -15.01800 1.000 54.87977  ? 362 LEU A O   1 
ATOM   2679 C CB  . LEU A 1 362 ? -77.78700 -16.47700 -17.14700 1.000 53.92754  ? 362 LEU A CB  1 
ATOM   2680 C CG  . LEU A 1 362 ? -78.34100 -17.88100 -17.37800 1.000 63.60156  ? 362 LEU A CG  1 
ATOM   2681 C CD1 . LEU A 1 362 ? -78.19600 -18.25100 -18.83100 1.000 70.83534  ? 362 LEU A CD1 1 
ATOM   2682 C CD2 . LEU A 1 362 ? -77.66300 -18.91500 -16.49300 1.000 61.62745  ? 362 LEU A CD2 1 
ATOM   2683 N N   . LEU A 1 363 ? -77.45400 -16.61600 -13.60200 1.000 47.82812  ? 363 LEU A N   1 
ATOM   2684 C CA  . LEU A 1 363 ? -76.52400 -16.74900 -12.48900 1.000 44.76218  ? 363 LEU A CA  1 
ATOM   2685 C C   . LEU A 1 363 ? -76.05500 -18.19300 -12.40500 1.000 44.85412  ? 363 LEU A C   1 
ATOM   2686 O O   . LEU A 1 363 ? -76.86700 -19.10200 -12.18200 1.000 43.85528  ? 363 LEU A O   1 
ATOM   2687 C CB  . LEU A 1 363 ? -77.17200 -16.32400 -11.17600 1.000 43.78257  ? 363 LEU A CB  1 
ATOM   2688 C CG  . LEU A 1 363 ? -77.79900 -14.93500 -11.16100 1.000 45.47261  ? 363 LEU A CG  1 
ATOM   2689 C CD1 . LEU A 1 363 ? -78.48100 -14.71400 -9.82300  1.000 39.84019  ? 363 LEU A CD1 1 
ATOM   2690 C CD2 . LEU A 1 363 ? -76.75600 -13.85800 -11.43100 1.000 46.56238  ? 363 LEU A CD2 1 
ATOM   2691 N N   . VAL A 1 364 ? -74.74900 -18.39700 -12.57900 1.000 40.64438  ? 364 VAL A N   1 
ATOM   2692 C CA  . VAL A 1 364 ? -74.14300 -19.72500 -12.58400 1.000 38.06087  ? 364 VAL A CA  1 
ATOM   2693 C C   . VAL A 1 364 ? -73.09300 -19.79700 -11.48400 1.000 42.24913  ? 364 VAL A C   1 
ATOM   2694 O O   . VAL A 1 364 ? -72.22700 -18.91700 -11.37300 1.000 39.89640  ? 364 VAL A O   1 
ATOM   2695 C CB  . VAL A 1 364 ? -73.51200 -20.05400 -13.94600 1.000 42.33053  ? 364 VAL A CB  1 
ATOM   2696 C CG1 . VAL A 1 364 ? -73.10700 -21.52300 -13.98700 1.000 42.93232  ? 364 VAL A CG1 1 
ATOM   2697 C CG2 . VAL A 1 364 ? -74.46600 -19.69700 -15.07500 1.000 45.98266  ? 364 VAL A CG2 1 
ATOM   2698 N N   . GLY A 1 365 ? -73.15600 -20.84900 -10.69100 1.000 44.13228  ? 365 GLY A N   1 
ATOM   2699 C CA  . GLY A 1 365 ? -72.24800 -20.97800 -9.58400  1.000 31.66920  ? 365 GLY A CA  1 
ATOM   2700 C C   . GLY A 1 365 ? -72.62100 -20.08600 -8.41500  1.000 35.02181  ? 365 GLY A C   1 
ATOM   2701 O O   . GLY A 1 365 ? -73.77100 -19.68700 -8.21200  1.000 39.98494  ? 365 GLY A O   1 
ATOM   2702 N N   . CYS A 1 366 ? -71.58800 -19.74600 -7.65500  1.000 40.25207  ? 366 CYS A N   1 
ATOM   2703 C CA  . CYS A 1 366 ? -71.70800 -19.06400 -6.37200  1.000 41.32054  ? 366 CYS A CA  1 
ATOM   2704 C C   . CYS A 1 366 ? -71.70300 -17.55600 -6.60300  1.000 43.62525  ? 366 CYS A C   1 
ATOM   2705 O O   . CYS A 1 366 ? -70.64200 -16.93300 -6.74800  1.000 37.77919  ? 366 CYS A O   1 
ATOM   2706 C CB  . CYS A 1 366 ? -70.56800 -19.49300 -5.45700  1.000 41.19924  ? 366 CYS A CB  1 
ATOM   2707 S SG  . CYS A 1 366 ? -70.52200 -18.55100 -3.96200  1.000 69.17788  ? 366 CYS A SG  1 
ATOM   2708 N N   . THR A 1 367 ? -72.89300 -16.96600 -6.60200  1.000 40.23666  ? 367 THR A N   1 
ATOM   2709 C CA  . THR A 1 367 ? -73.09000 -15.58700 -7.00600  1.000 41.02601  ? 367 THR A CA  1 
ATOM   2710 C C   . THR A 1 367 ? -73.92700 -14.85100 -5.96900  1.000 44.66406  ? 367 THR A C   1 
ATOM   2711 O O   . THR A 1 367 ? -74.66800 -15.48400 -5.20700  1.000 50.64221  ? 367 THR A O   1 
ATOM   2712 C CB  . THR A 1 367 ? -73.78500 -15.54600 -8.37300  1.000 42.28038  ? 367 THR A CB  1 
ATOM   2713 O OG1 . THR A 1 367 ? -73.43900 -14.34000 -9.04500  1.000 44.54352  ? 367 THR A OG1 1 
ATOM   2714 C CG2 . THR A 1 367 ? -75.29600 -15.61700 -8.21900  1.000 43.12533  ? 367 THR A CG2 1 
ATOM   2715 N N   . PRO A 1 368 ? -73.80300 -13.52700 -5.87900  1.000 42.45381  ? 368 PRO A N   1 
ATOM   2716 C CA  . PRO A 1 368 ? -74.74400 -12.76200 -5.04800  1.000 43.62024  ? 368 PRO A CA  1 
ATOM   2717 C C   . PRO A 1 368 ? -76.13700 -12.75000 -5.67400  1.000 45.92053  ? 368 PRO A C   1 
ATOM   2718 O O   . PRO A 1 368 ? -76.32400 -13.03600 -6.85900  1.000 45.01729  ? 368 PRO A O   1 
ATOM   2719 C CB  . PRO A 1 368 ? -74.13700 -11.35600 -4.99100  1.000 42.87595  ? 368 PRO A CB  1 
ATOM   2720 C CG  . PRO A 1 368 ? -73.11200 -11.30200 -6.09800  1.000 41.99939  ? 368 PRO A CG  1 
ATOM   2721 C CD  . PRO A 1 368 ? -72.67200 -12.70900 -6.35800  1.000 42.74015  ? 368 PRO A CD  1 
ATOM   2722 N N   . ALA A 1 369 ? -77.13000 -12.43100 -4.84500  1.000 46.40334  ? 369 ALA A N   1 
ATOM   2723 C CA  . ALA A 1 369 ? -78.52000 -12.64500 -5.22700  1.000 48.09487  ? 369 ALA A CA  1 
ATOM   2724 C C   . ALA A 1 369 ? -78.91100 -11.76300 -6.41500  1.000 45.60633  ? 369 ALA A C   1 
ATOM   2725 O O   . ALA A 1 369 ? -78.30200 -10.71900 -6.67800  1.000 49.37678  ? 369 ALA A O   1 
ATOM   2726 C CB  . ALA A 1 369 ? -79.44500 -12.38900 -4.03900  1.000 44.05546  ? 369 ALA A CB  1 
ATOM   2727 N N   . GLN A 1 370 ? -79.95100 -12.20700 -7.13400  1.000 42.39638  ? 370 GLN A N   1 
ATOM   2728 C CA  . GLN A 1 370 ? -80.31500 -11.60000 -8.41600  1.000 43.21649  ? 370 GLN A CA  1 
ATOM   2729 C C   . GLN A 1 370 ? -80.54300 -10.09300 -8.31000  1.000 47.86353  ? 370 GLN A C   1 
ATOM   2730 O O   . GLN A 1 370 ? -80.16800 -9.34500  -9.22100  1.000 50.18052  ? 370 GLN A O   1 
ATOM   2731 C CB  . GLN A 1 370 ? -81.55700 -12.28100 -8.98600  1.000 47.83129  ? 370 GLN A CB  1 
ATOM   2732 C CG  . GLN A 1 370 ? -82.22400 -11.50900 -10.11100 1.000 45.94762  ? 370 GLN A CG  1 
ATOM   2733 C CD  . GLN A 1 370 ? -83.36900 -12.26700 -10.73200 1.000 53.35241  ? 370 GLN A CD  1 
ATOM   2734 O OE1 . GLN A 1 370 ? -83.64200 -13.41400 -10.36900 1.000 61.42259  ? 370 GLN A OE1 1 
ATOM   2735 N NE2 . GLN A 1 370 ? -84.04900 -11.63700 -11.68400 1.000 66.15469  ? 370 GLN A NE2 1 
ATOM   2736 N N   . ASP A 1 371 ? -81.16300 -9.61800  -7.22100  1.000 46.53153  ? 371 ASP A N   1 
ATOM   2737 C CA  . ASP A 1 371 ? -81.37000 -8.17600  -7.09500  1.000 44.86580  ? 371 ASP A CA  1 
ATOM   2738 C C   . ASP A 1 371 ? -80.05000 -7.44200  -6.90200  1.000 49.61812  ? 371 ASP A C   1 
ATOM   2739 O O   . ASP A 1 371 ? -79.84900 -6.36500  -7.47600  1.000 51.44718  ? 371 ASP A O   1 
ATOM   2740 C CB  . ASP A 1 371 ? -82.32400 -7.85600  -5.94500  1.000 45.69168  ? 371 ASP A CB  1 
ATOM   2741 C CG  . ASP A 1 371 ? -83.79300 -8.04900  -6.31900  1.000 50.59099  ? 371 ASP A CG  1 
ATOM   2742 O OD1 . ASP A 1 371 ? -84.11800 -8.04700  -7.54200  1.000 53.96184  ? 371 ASP A OD1 1 
ATOM   2743 O OD2 . ASP A 1 371 ? -84.61400 -8.20100  -5.37700  1.000 40.98487  ? 371 ASP A OD2 1 
ATOM   2744 N N   . GLU A 1 372 ? -79.14500 -8.00200  -6.08700  1.000 48.90410  ? 372 GLU A N   1 
ATOM   2745 C CA  . GLU A 1 372 ? -77.81300 -7.41800  -5.92500  1.000 49.30486  ? 372 GLU A CA  1 
ATOM   2746 C C   . GLU A 1 372 ? -77.06500 -7.36400  -7.25600  1.000 48.82249  ? 372 GLU A C   1 
ATOM   2747 O O   . GLU A 1 372 ? -76.41500 -6.36300  -7.57100  1.000 52.66004  ? 372 GLU A O   1 
ATOM   2748 C CB  . GLU A 1 372 ? -77.00700 -8.21800  -4.90400  1.000 51.19789  ? 372 GLU A CB  1 
ATOM   2749 C CG  . GLU A 1 372 ? -77.65900 -8.39600  -3.54400  1.000 47.55467  ? 372 GLU A CG  1 
ATOM   2750 C CD  . GLU A 1 372 ? -76.79700 -9.23800  -2.60200  1.000 55.03923  ? 372 GLU A CD  1 
ATOM   2751 O OE1 . GLU A 1 372 ? -76.67700 -10.46900 -2.83500  1.000 55.08519  ? 372 GLU A OE1 1 
ATOM   2752 O OE2 . GLU A 1 372 ? -76.22400 -8.66900  -1.64100  1.000 51.94220  ? 372 GLU A OE2 1 
ATOM   2753 N N   . VAL A 1 373 ? -77.14000 -8.43400  -8.05000  1.000 46.92913  ? 373 VAL A N   1 
ATOM   2754 C CA  . VAL A 1 373 ? -76.49000 -8.43700  -9.36000  1.000 47.19926  ? 373 VAL A CA  1 
ATOM   2755 C C   . VAL A 1 373 ? -77.08800 -7.35600  -10.25000 1.000 54.23325  ? 373 VAL A C   1 
ATOM   2756 O O   . VAL A 1 373 ? -76.36700 -6.61000  -10.92500 1.000 52.85927  ? 373 VAL A O   1 
ATOM   2757 C CB  . VAL A 1 373 ? -76.61100 -9.82300  -10.01600 1.000 46.98855  ? 373 VAL A CB  1 
ATOM   2758 C CG1 . VAL A 1 373 ? -76.10200 -9.77800  -11.44800 1.000 48.37104  ? 373 VAL A CG1 1 
ATOM   2759 C CG2 . VAL A 1 373 ? -75.86600 -10.86600 -9.20300  1.000 45.27395  ? 373 VAL A CG2 1 
ATOM   2760 N N   . GLU A 1 374 ? -78.42400 -7.26400  -10.27400 1.000 57.16392  ? 374 GLU A N   1 
ATOM   2761 C CA  . GLU A 1 374 ? -79.08400 -6.23100  -11.06900 1.000 51.87632  ? 374 GLU A CA  1 
ATOM   2762 C C   . GLU A 1 374 ? -78.65400 -4.85100  -10.61100 1.000 53.66295  ? 374 GLU A C   1 
ATOM   2763 O O   . GLU A 1 374 ? -78.42800 -3.95400  -11.43400 1.000 56.24013  ? 374 GLU A O   1 
ATOM   2764 C CB  . GLU A 1 374 ? -80.60400 -6.38700  -10.98300 1.000 49.31999  ? 374 GLU A CB  1 
ATOM   2765 C CG  . GLU A 1 374 ? -81.17600 -7.49000  -11.90900 1.000 55.51689  ? 374 GLU A CG  1 
ATOM   2766 C CD  . GLU A 1 374 ? -82.55700 -8.00100  -11.47600 1.000 64.74175  ? 374 GLU A CD  1 
ATOM   2767 O OE1 . GLU A 1 374 ? -83.04600 -7.61200  -10.38100 1.000 64.27044  ? 374 GLU A OE1 1 
ATOM   2768 O OE2 . GLU A 1 374 ? -83.15100 -8.80300  -12.23500 1.000 62.09406  ? 374 GLU A OE2 1 
ATOM   2769 N N   . ALA A 1 375 ? -78.50600 -4.66900  -9.30000  1.000 49.19396  ? 375 ALA A N   1 
ATOM   2770 C CA  . ALA A 1 375 ? -78.04400 -3.38600  -8.79800  1.000 43.62970  ? 375 ALA A CA  1 
ATOM   2771 C C   . ALA A 1 375 ? -76.61300 -3.12400  -9.24800  1.000 48.69832  ? 375 ALA A C   1 
ATOM   2772 O O   . ALA A 1 375 ? -76.30100 -2.04200  -9.75300  1.000 52.65772  ? 375 ALA A O   1 
ATOM   2773 C CB  . ALA A 1 375 ? -78.17900 -3.34300  -7.27800  1.000 47.12304  ? 375 ALA A CB  1 
ATOM   2774 N N   . LEU A 1 376 ? -75.73600 -4.12400  -9.12400  1.000 53.20219  ? 376 LEU A N   1 
ATOM   2775 C CA  . LEU A 1 376 ? -74.35400 -3.94100  -9.56600  1.000 55.18055  ? 376 LEU A CA  1 
ATOM   2776 C C   . LEU A 1 376 ? -74.28900 -3.70000  -11.07500 1.000 52.31277  ? 376 LEU A C   1 
ATOM   2777 O O   . LEU A 1 376 ? -73.50100 -2.87400  -11.55300 1.000 51.48158  ? 376 LEU A O   1 
ATOM   2778 C CB  . LEU A 1 376 ? -73.51000 -5.15600  -9.15800  1.000 51.75280  ? 376 LEU A CB  1 
ATOM   2779 C CG  . LEU A 1 376 ? -72.06400 -5.22600  -9.66800  1.000 49.20269  ? 376 LEU A CG  1 
ATOM   2780 C CD1 . LEU A 1 376 ? -71.25900 -4.05900  -9.17500  1.000 46.75621  ? 376 LEU A CD1 1 
ATOM   2781 C CD2 . LEU A 1 376 ? -71.43000 -6.50100  -9.22800  1.000 44.07539  ? 376 LEU A CD2 1 
ATOM   2782 N N   . VAL A 1 377 ? -75.13400 -4.39800  -11.83200 1.000 46.42431  ? 377 VAL A N   1 
ATOM   2783 C CA  . VAL A 1 377 ? -75.13600 -4.27700  -13.28700 1.000 50.25219  ? 377 VAL A CA  1 
ATOM   2784 C C   . VAL A 1 377 ? -75.39400 -2.83500  -13.71100 1.000 54.79870  ? 377 VAL A C   1 
ATOM   2785 O O   . VAL A 1 377 ? -74.67200 -2.27300  -14.54400 1.000 59.15987  ? 377 VAL A O   1 
ATOM   2786 C CB  . VAL A 1 377 ? -76.18200 -5.23200  -13.88900 1.000 57.84561  ? 377 VAL A CB  1 
ATOM   2787 C CG1 . VAL A 1 377 ? -76.57500 -4.77900  -15.27900 1.000 59.08328  ? 377 VAL A CG1 1 
ATOM   2788 C CG2 . VAL A 1 377 ? -75.65300 -6.66000  -13.90600 1.000 52.85470  ? 377 VAL A CG2 1 
ATOM   2789 N N   . ALA A 1 378 ? -76.43200 -2.21500  -13.14700 1.000 55.71349  ? 378 ALA A N   1 
ATOM   2790 C CA  . ALA A 1 378 ? -76.76800 -0.84800  -13.52800 1.000 54.11680  ? 378 ALA A CA  1 
ATOM   2791 C C   . ALA A 1 378 ? -75.66400 0.13600   -13.15100 1.000 56.24955  ? 378 ALA A C   1 
ATOM   2792 O O   . ALA A 1 378 ? -75.49300 1.15800   -13.82500 1.000 59.47590  ? 378 ALA A O   1 
ATOM   2793 C CB  . ALA A 1 378 ? -78.09900 -0.44200  -12.89400 1.000 49.25108  ? 378 ALA A CB  1 
ATOM   2794 N N   . TRP A 1 379 ? -74.90100 -0.15000  -12.09300 1.000 57.20673  ? 379 TRP A N   1 
ATOM   2795 C CA  . TRP A 1 379 ? -73.77600 0.71400   -11.73800 1.000 56.40663  ? 379 TRP A CA  1 
ATOM   2796 C C   . TRP A 1 379 ? -72.59800 0.53100   -12.68000 1.000 61.59924  ? 379 TRP A C   1 
ATOM   2797 O O   . TRP A 1 379 ? -71.87100 1.49400   -12.95400 1.000 59.00936  ? 379 TRP A O   1 
ATOM   2798 C CB  . TRP A 1 379 ? -73.33000 0.43600   -10.30600 1.000 54.40557  ? 379 TRP A CB  1 
ATOM   2799 C CG  . TRP A 1 379 ? -72.02000 1.05700   -9.90900  1.000 56.03846  ? 379 TRP A CG  1 
ATOM   2800 C CD1 . TRP A 1 379 ? -71.82200 2.31700   -9.42400  1.000 57.23168  ? 379 TRP A CD1 1 
ATOM   2801 C CD2 . TRP A 1 379 ? -70.73300 0.43000   -9.92900  1.000 55.90309  ? 379 TRP A CD2 1 
ATOM   2802 N NE1 . TRP A 1 379 ? -70.49100 2.51700   -9.14500  1.000 56.11853  ? 379 TRP A NE1 1 
ATOM   2803 C CE2 . TRP A 1 379 ? -69.80100 1.37400   -9.44500  1.000 54.65018  ? 379 TRP A CE2 1 
ATOM   2804 C CE3 . TRP A 1 379 ? -70.27700 -0.83700  -10.30800 1.000 53.73483  ? 379 TRP A CE3 1 
ATOM   2805 C CZ2 . TRP A 1 379 ? -68.44500 1.09000   -9.32600  1.000 51.59027  ? 379 TRP A CZ2 1 
ATOM   2806 C CZ3 . TRP A 1 379 ? -68.93300 -1.11700  -10.19100 1.000 47.89024  ? 379 TRP A CZ3 1 
ATOM   2807 C CH2 . TRP A 1 379 ? -68.03000 -0.15800  -9.70300  1.000 50.06673  ? 379 TRP A CH2 1 
ATOM   2808 N N   . LEU A 1 380 ? -72.38700 -0.69400  -13.16700 1.000 61.71372  ? 380 LEU A N   1 
ATOM   2809 C CA  . LEU A 1 380 ? -71.31900 -0.92500  -14.12800 1.000 57.74805  ? 380 LEU A CA  1 
ATOM   2810 C C   . LEU A 1 380 ? -71.57100 -0.15600  -15.41800 1.000 62.82361  ? 380 LEU A C   1 
ATOM   2811 O O   . LEU A 1 380 ? -70.63600 0.39100   -16.01600 1.000 64.45433  ? 380 LEU A O   1 
ATOM   2812 C CB  . LEU A 1 380 ? -71.18700 -2.41800  -14.41200 1.000 55.77443  ? 380 LEU A CB  1 
ATOM   2813 C CG  . LEU A 1 380 ? -70.26800 -3.27000  -13.53800 1.000 52.30663  ? 380 LEU A CG  1 
ATOM   2814 C CD1 . LEU A 1 380 ? -70.29000 -4.68900  -14.06200 1.000 50.10944  ? 380 LEU A CD1 1 
ATOM   2815 C CD2 . LEU A 1 380 ? -68.84100 -2.72100  -13.51400 1.000 51.18723  ? 380 LEU A CD2 1 
ATOM   2816 N N   . ALA A 1 381 ? -72.83000 -0.08800  -15.85700 1.000 60.03404  ? 381 ALA A N   1 
ATOM   2817 C CA  . ALA A 1 381 ? -73.13700 0.58800   -17.11500 1.000 63.27554  ? 381 ALA A CA  1 
ATOM   2818 C C   . ALA A 1 381 ? -72.83100 2.10300   -17.09200 1.000 67.51009  ? 381 ALA A C   1 
ATOM   2819 O O   . ALA A 1 381 ? -73.12000 2.74400   -18.10700 1.000 72.80527  ? 381 ALA A O   1 
ATOM   2820 C CB  . ALA A 1 381 ? -74.60100 0.36400   -17.49900 1.000 60.86326  ? 381 ALA A CB  1 
ATOM   2821 N N   . THR A 1 382 ? -72.25700 2.67200   -16.02300 1.000 66.50669  ? 382 THR A N   1 
ATOM   2822 C CA  . THR A 1 382 ? -71.96000 4.09800   -15.91300 1.000 64.36686  ? 382 THR A CA  1 
ATOM   2823 C C   . THR A 1 382 ? -70.49000 4.33500   -15.58300 1.000 67.82178  ? 382 THR A C   1 
ATOM   2824 O O   . THR A 1 382 ? -70.14600 5.29800   -14.88700 1.000 70.06277  ? 382 THR A O   1 
ATOM   2825 C CB  . THR A 1 382 ? -72.83400 4.75500   -14.84500 1.000 64.55294  ? 382 THR A CB  1 
ATOM   2826 O OG1 . THR A 1 382 ? -72.38900 4.32800   -13.54900 1.000 63.31562  ? 382 THR A OG1 1 
ATOM   2827 C CG2 . THR A 1 382 ? -74.30900 4.36900   -15.02900 1.000 62.13176  ? 382 THR A CG2 1 
ATOM   2828 N N   . GLN A 1 383 ? -69.60900 3.47000   -16.06000 1.000 67.30729  ? 383 GLN A N   1 
ATOM   2829 C CA  . GLN A 1 383 ? -68.22200 3.54400   -15.64200 1.000 64.86408  ? 383 GLN A CA  1 
ATOM   2830 C C   . GLN A 1 383 ? -67.32300 3.66000   -16.86700 1.000 65.05192  ? 383 GLN A C   1 
ATOM   2831 O O   . GLN A 1 383 ? -67.66400 3.16300   -17.94300 1.000 65.30168  ? 383 GLN A O   1 
ATOM   2832 C CB  . GLN A 1 383 ? -67.84500 2.31300   -14.80400 1.000 61.58798  ? 383 GLN A CB  1 
ATOM   2833 C CG  . GLN A 1 383 ? -68.68000 2.18100   -13.51900 1.000 59.49059  ? 383 GLN A CG  1 
ATOM   2834 C CD  . GLN A 1 383 ? -68.49700 3.36100   -12.56500 1.000 61.96479  ? 383 GLN A CD  1 
ATOM   2835 O OE1 . GLN A 1 383 ? -69.46800 3.89500   -12.02600 1.000 59.09353  ? 383 GLN A OE1 1 
ATOM   2836 N NE2 . GLN A 1 383 ? -67.24300 3.76300   -12.34600 1.000 64.93540  ? 383 GLN A NE2 1 
ATOM   2837 N N   . PRO A 1 384 ? -66.18700 4.32500   -16.72800 1.000 66.93591  ? 384 PRO A N   1 
ATOM   2838 C CA  . PRO A 1 384 ? -65.34500 4.66700   -17.89400 1.000 67.53843  ? 384 PRO A CA  1 
ATOM   2839 C C   . PRO A 1 384 ? -64.49300 3.51200   -18.41400 1.000 71.67867  ? 384 PRO A C   1 
ATOM   2840 O O   . PRO A 1 384 ? -63.26800 3.62500   -18.53700 1.000 73.43010  ? 384 PRO A O   1 
ATOM   2841 C CB  . PRO A 1 384 ? -64.47800 5.80200   -17.35100 1.000 69.57993  ? 384 PRO A CB  1 
ATOM   2842 C CG  . PRO A 1 384 ? -64.31800 5.46900   -15.89500 1.000 72.89682  ? 384 PRO A CG  1 
ATOM   2843 C CD  . PRO A 1 384 ? -65.63900 4.87300   -15.47500 1.000 70.53852  ? 384 PRO A CD  1 
ATOM   2844 N N   . PHE A 1 385 ? -65.13200 2.39600   -18.73600 1.000 65.95769  ? 385 PHE A N   1 
ATOM   2845 C CA  . PHE A 1 385 ? -64.40300 1.28600   -19.32000 1.000 66.52619  ? 385 PHE A CA  1 
ATOM   2846 C C   . PHE A 1 385 ? -65.04700 0.86300   -20.63400 1.000 67.73537  ? 385 PHE A C   1 
ATOM   2847 O O   . PHE A 1 385 ? -66.25700 1.02100   -20.85200 1.000 62.38569  ? 385 PHE A O   1 
ATOM   2848 C CB  . PHE A 1 385 ? -64.29100 0.10000   -18.34800 1.000 55.92731  ? 385 PHE A CB  1 
ATOM   2849 C CG  . PHE A 1 385 ? -65.54600 -0.70500  -18.21400 1.000 54.65947  ? 385 PHE A CG  1 
ATOM   2850 C CD1 . PHE A 1 385 ? -66.48900 -0.38400  -17.26000 1.000 50.45261  ? 385 PHE A CD1 1 
ATOM   2851 C CD2 . PHE A 1 385 ? -65.76600 -1.81100  -19.02500 1.000 55.71507  ? 385 PHE A CD2 1 
ATOM   2852 C CE1 . PHE A 1 385 ? -67.64000 -1.14200  -17.12400 1.000 58.27657  ? 385 PHE A CE1 1 
ATOM   2853 C CE2 . PHE A 1 385 ? -66.91300 -2.56800  -18.90300 1.000 55.71187  ? 385 PHE A CE2 1 
ATOM   2854 C CZ  . PHE A 1 385 ? -67.85100 -2.23800  -17.94800 1.000 59.32164  ? 385 PHE A CZ  1 
ATOM   2855 N N   . GLN A 1 386 ? -64.20000 0.29300   -21.48900 1.000 68.85158  ? 386 GLN A N   1 
ATOM   2856 C CA  . GLN A 1 386 ? -64.42800 0.08400   -22.91100 1.000 66.32482  ? 386 GLN A CA  1 
ATOM   2857 C C   . GLN A 1 386 ? -64.96300 -1.30800  -23.22300 1.000 64.59577  ? 386 GLN A C   1 
ATOM   2858 O O   . GLN A 1 386 ? -65.95500 -1.44300  -23.94900 1.000 62.82174  ? 386 GLN A O   1 
ATOM   2859 C CB  . GLN A 1 386 ? -63.11200 0.32100   -23.67400 1.000 69.33106  ? 386 GLN A CB  1 
ATOM   2860 C CG  . GLN A 1 386 ? -62.29300 1.56400   -23.24100 1.000 70.04832  ? 386 GLN A CG  1 
ATOM   2861 C CD  . GLN A 1 386 ? -61.52900 1.39700   -21.91300 1.000 77.25285  ? 386 GLN A CD  1 
ATOM   2862 O OE1 . GLN A 1 386 ? -61.71500 0.41600   -21.18100 1.000 74.46908  ? 386 GLN A OE1 1 
ATOM   2863 N NE2 . GLN A 1 386 ? -60.67200 2.36900   -21.60200 1.000 75.02259  ? 386 GLN A NE2 1 
ATOM   2864 N N   . THR A 1 387 ? -64.30200 -2.35100  -22.71500 1.000 58.86010  ? 387 THR A N   1 
ATOM   2865 C CA  . THR A 1 387 ? -64.77900 -3.71600  -22.90900 1.000 62.30136  ? 387 THR A CA  1 
ATOM   2866 C C   . THR A 1 387 ? -64.64400 -4.54700  -21.63800 1.000 57.14693  ? 387 THR A C   1 
ATOM   2867 O O   . THR A 1 387 ? -65.54900 -5.31900  -21.31600 1.000 56.35592  ? 387 THR A O   1 
ATOM   2868 C CB  . THR A 1 387 ? -64.03700 -4.40600  -24.05700 1.000 60.32348  ? 387 THR A CB  1 
ATOM   2869 O OG1 . THR A 1 387 ? -62.64800 -4.05300  -24.00600 1.000 64.08794  ? 387 THR A OG1 1 
ATOM   2870 C CG2 . THR A 1 387 ? -64.63900 -4.00100  -25.39700 1.000 60.05227  ? 387 THR A CG2 1 
ATOM   2871 N N   . SER A 1 388 ? -63.53500 -4.40700  -20.91000 1.000 54.09022  ? 388 SER A N   1 
ATOM   2872 C CA  . SER A 1 388 ? -63.33700 -5.14200  -19.67000 1.000 49.08735  ? 388 SER A CA  1 
ATOM   2873 C C   . SER A 1 388 ? -63.23000 -4.18500  -18.48900 1.000 45.28368  ? 388 SER A C   1 
ATOM   2874 O O   . SER A 1 388 ? -62.87900 -3.01600  -18.64600 1.000 44.59515  ? 388 SER A O   1 
ATOM   2875 C CB  . SER A 1 388 ? -62.08600 -6.01800  -19.72100 1.000 50.49269  ? 388 SER A CB  1 
ATOM   2876 O OG  . SER A 1 388 ? -60.92800 -5.23600  -19.48500 1.000 56.56304  ? 388 SER A OG  1 
ATOM   2877 N N   . PHE A 1 389 ? -63.56000 -4.70600  -17.30600 1.000 47.57749  ? 389 PHE A N   1 
ATOM   2878 C CA  . PHE A 1 389 ? -63.37200 -4.03200  -16.02600 1.000 46.30979  ? 389 PHE A CA  1 
ATOM   2879 C C   . PHE A 1 389 ? -63.09200 -5.09300  -14.96800 1.000 45.12914  ? 389 PHE A C   1 
ATOM   2880 O O   . PHE A 1 389 ? -63.70800 -6.16300  -14.97900 1.000 46.67094  ? 389 PHE A O   1 
ATOM   2881 C CB  . PHE A 1 389 ? -64.59900 -3.20300  -15.62300 1.000 44.12746  ? 389 PHE A CB  1 
ATOM   2882 C CG  . PHE A 1 389 ? -64.58100 -2.76300  -14.19000 1.000 43.41412  ? 389 PHE A CG  1 
ATOM   2883 C CD1 . PHE A 1 389 ? -63.73800 -1.74200  -13.77600 1.000 40.65005  ? 389 PHE A CD1 1 
ATOM   2884 C CD2 . PHE A 1 389 ? -65.40100 -3.37300  -13.25300 1.000 41.31496  ? 389 PHE A CD2 1 
ATOM   2885 C CE1 . PHE A 1 389 ? -63.70300 -1.34200  -12.46200 1.000 34.66567  ? 389 PHE A CE1 1 
ATOM   2886 C CE2 . PHE A 1 389 ? -65.37800 -2.97600  -11.93000 1.000 40.01177  ? 389 PHE A CE2 1 
ATOM   2887 C CZ  . PHE A 1 389 ? -64.52200 -1.95600  -11.53500 1.000 43.29870  ? 389 PHE A CZ  1 
ATOM   2888 N N   . HIS A 1 390 ? -62.16800 -4.79700  -14.05600 1.000 44.81310  ? 390 HIS A N   1 
ATOM   2889 C CA  . HIS A 1 390 ? -61.81000 -5.77300  -13.03700 1.000 44.13628  ? 390 HIS A CA  1 
ATOM   2890 C C   . HIS A 1 390 ? -61.36600 -5.05800  -11.76500 1.000 42.58506  ? 390 HIS A C   1 
ATOM   2891 O O   . HIS A 1 390 ? -60.86300 -3.93500  -11.80900 1.000 46.25587  ? 390 HIS A O   1 
ATOM   2892 C CB  . HIS A 1 390 ? -60.71900 -6.73800  -13.54400 1.000 41.28372  ? 390 HIS A CB  1 
ATOM   2893 C CG  . HIS A 1 390 ? -59.34000 -6.14800  -13.60600 1.000 40.47538  ? 390 HIS A CG  1 
ATOM   2894 N ND1 . HIS A 1 390 ? -58.78900 -5.65900  -14.77400 1.000 42.41767  ? 390 HIS A ND1 1 
ATOM   2895 C CD2 . HIS A 1 390 ? -58.38900 -5.99600  -12.65100 1.000 45.10886  ? 390 HIS A CD2 1 
ATOM   2896 C CE1 . HIS A 1 390 ? -57.56500 -5.21900  -14.53200 1.000 48.62554  ? 390 HIS A CE1 1 
ATOM   2897 N NE2 . HIS A 1 390 ? -57.29900 -5.40400  -13.25000 1.000 40.53207  ? 390 HIS A NE2 1 
ATOM   2898 N N   . THR A 1 391 ? -61.58000 -5.71700  -10.63000 1.000 43.80891  ? 391 THR A N   1 
ATOM   2899 C CA  . THR A 1 391 ? -61.08300 -5.24800  -9.34500  1.000 38.47613  ? 391 THR A CA  1 
ATOM   2900 C C   . THR A 1 391 ? -60.99300 -6.44200  -8.40800  1.000 43.02490  ? 391 THR A C   1 
ATOM   2901 O O   . THR A 1 391 ? -61.67300 -7.45600  -8.60400  1.000 48.37389  ? 391 THR A O   1 
ATOM   2902 C CB  . THR A 1 391 ? -61.98200 -4.17700  -8.73000  1.000 36.00580  ? 391 THR A CB  1 
ATOM   2903 O OG1 . THR A 1 391 ? -61.58500 -3.95900  -7.36900  1.000 34.60725  ? 391 THR A OG1 1 
ATOM   2904 C CG2 . THR A 1 391 ? -63.44800 -4.62200  -8.75700  1.000 39.80091  ? 391 THR A CG2 1 
ATOM   2905 N N   . ASP A 1 392 ? -60.14600 -6.31300  -7.38400  1.000 42.48963  ? 392 ASP A N   1 
ATOM   2906 C CA  . ASP A 1 392 ? -60.06500 -7.31900  -6.33000  1.000 42.04387  ? 392 ASP A CA  1 
ATOM   2907 C C   . ASP A 1 392 ? -60.50600 -6.77700  -4.97100  1.000 40.42891  ? 392 ASP A C   1 
ATOM   2908 O O   . ASP A 1 392 ? -60.36500 -7.46800  -3.95300  1.000 38.81489  ? 392 ASP A O   1 
ATOM   2909 C CB  . ASP A 1 392 ? -58.64800 -7.90500  -6.25700  1.000 47.04410  ? 392 ASP A CB  1 
ATOM   2910 C CG  . ASP A 1 392 ? -57.58700 -6.88300  -5.87300  1.000 48.61942  ? 392 ASP A CG  1 
ATOM   2911 O OD1 . ASP A 1 392 ? -57.90400 -5.77900  -5.37600  1.000 49.50771  ? 392 ASP A OD1 1 
ATOM   2912 O OD2 . ASP A 1 392 ? -56.39800 -7.20600  -6.07400  1.000 53.51214  ? 392 ASP A OD2 1 
ATOM   2913 N N   . ARG A 1 393 ? -61.03200 -5.55400  -4.93700  1.000 36.78116  ? 393 ARG A N   1 
ATOM   2914 C CA  . ARG A 1 393 ? -61.55700 -4.93100  -3.73100  1.000 37.70538  ? 393 ARG A CA  1 
ATOM   2915 C C   . ARG A 1 393 ? -62.87300 -4.26000  -4.09200  1.000 40.02640  ? 393 ARG A C   1 
ATOM   2916 O O   . ARG A 1 393 ? -63.05100 -3.05300  -3.91600  1.000 44.29197  ? 393 ARG A O   1 
ATOM   2917 C CB  . ARG A 1 393 ? -60.57800 -3.91600  -3.14300  1.000 42.94205  ? 393 ARG A CB  1 
ATOM   2918 C CG  . ARG A 1 393 ? -59.30600 -4.54000  -2.57800  1.000 50.92311  ? 393 ARG A CG  1 
ATOM   2919 C CD  . ARG A 1 393 ? -58.33300 -3.48700  -2.02400  1.000 62.61132  ? 393 ARG A CD  1 
ATOM   2920 N NE  . ARG A 1 393 ? -57.53800 -2.86500  -3.08300  1.000 65.71198  ? 393 ARG A NE  1 
ATOM   2921 C CZ  . ARG A 1 393 ? -56.34900 -3.29900  -3.48000  1.000 69.26482  ? 393 ARG A CZ  1 
ATOM   2922 N NH1 . ARG A 1 393 ? -55.76200 -4.33200  -2.89400  1.000 61.72983  ? 393 ARG A NH1 1 
ATOM   2923 N NH2 . ARG A 1 393 ? -55.73600 -2.68500  -4.49300  1.000 67.79050  ? 393 ARG A NH2 1 
ATOM   2924 N N   . LEU A 1 394 ? -63.79200 -5.05800  -4.64500  1.000 31.62248  ? 394 LEU A N   1 
ATOM   2925 C CA  . LEU A 1 394 ? -65.04500 -4.50300  -5.14600  1.000 39.34205  ? 394 LEU A CA  1 
ATOM   2926 C C   . LEU A 1 394 ? -65.69500 -3.57100  -4.13400  1.000 42.51192  ? 394 LEU A C   1 
ATOM   2927 O O   . LEU A 1 394 ? -66.25600 -2.53600  -4.50700  1.000 47.92540  ? 394 LEU A O   1 
ATOM   2928 C CB  . LEU A 1 394 ? -66.02400 -5.62200  -5.51700  1.000 33.91555  ? 394 LEU A CB  1 
ATOM   2929 C CG  . LEU A 1 394 ? -67.37600 -5.03100  -5.93900  1.000 34.88945  ? 394 LEU A CG  1 
ATOM   2930 C CD1 . LEU A 1 394 ? -67.16300 -4.15000  -7.16700  1.000 35.22943  ? 394 LEU A CD1 1 
ATOM   2931 C CD2 . LEU A 1 394 ? -68.43800 -6.08900  -6.20700  1.000 31.21208  ? 394 LEU A CD2 1 
ATOM   2932 N N   . GLY A 1 395 ? -65.60100 -3.90400  -2.84300  1.000 43.59693  ? 395 GLY A N   1 
ATOM   2933 C CA  . GLY A 1 395 ? -66.36400 -3.17500  -1.83900  1.000 43.63764  ? 395 GLY A CA  1 
ATOM   2934 C C   . GLY A 1 395 ? -65.91300 -1.74300  -1.64200  1.000 45.75440  ? 395 GLY A C   1 
ATOM   2935 O O   . GLY A 1 395 ? -66.72400 -0.88200  -1.29100  1.000 52.39978  ? 395 GLY A O   1 
ATOM   2936 N N   . THR A 1 396 ? -64.62700 -1.47300  -1.85500  1.000 46.20781  ? 396 THR A N   1 
ATOM   2937 C CA  . THR A 1 396 ? -64.03100 -0.13700  -1.75700  1.000 46.09282  ? 396 THR A CA  1 
ATOM   2938 C C   . THR A 1 396 ? -64.07400 0.58200   -3.09400  1.000 46.18720  ? 396 THR A C   1 
ATOM   2939 O O   . THR A 1 396 ? -63.06600 1.09600   -3.57200  1.000 53.12372  ? 396 THR A O   1 
ATOM   2940 C CB  . THR A 1 396 ? -62.59100 -0.23800  -1.27300  1.000 44.68087  ? 396 THR A CB  1 
ATOM   2941 O OG1 . THR A 1 396 ? -61.73300 -0.40800  -2.41400  1.000 44.32675  ? 396 THR A OG1 1 
ATOM   2942 C CG2 . THR A 1 396 ? -62.42700 -1.42500  -0.33300  1.000 40.47473  ? 396 THR A CG2 1 
ATOM   2943 N N   . VAL A 1 397 ? -65.24300 0.57400   -3.71900  1.000 45.74836  ? 397 VAL A N   1 
ATOM   2944 C CA  . VAL A 1 397 ? -65.48300 1.19800   -5.01300  1.000 46.52925  ? 397 VAL A CA  1 
ATOM   2945 C C   . VAL A 1 397 ? -66.96500 1.01500   -5.26900  1.000 50.77670  ? 397 VAL A C   1 
ATOM   2946 O O   . VAL A 1 397 ? -67.57400 1.73500   -6.06900  1.000 51.31919  ? 397 VAL A O   1 
ATOM   2947 C CB  . VAL A 1 397 ? -64.64000 0.57800   -6.14100  1.000 50.25873  ? 397 VAL A CB  1 
ATOM   2948 C CG1 . VAL A 1 397 ? -65.32400 -0.63900  -6.73900  1.000 48.19037  ? 397 VAL A CG1 1 
ATOM   2949 C CG2 . VAL A 1 397 ? -64.39000 1.60500   -7.21300  1.000 62.84935  ? 397 VAL A CG2 1 
ATOM   2950 N N   . TYR A 1 398 ? -67.54100 0.04100   -4.56900  1.000 46.47340  ? 398 TYR A N   1 
ATOM   2951 C CA  . TYR A 1 398 ? -68.95900 -0.28200  -4.68300  1.000 43.48026  ? 398 TYR A CA  1 
ATOM   2952 C C   . TYR A 1 398 ? -69.41500 -0.78200  -3.32800  1.000 51.53865  ? 398 TYR A C   1 
ATOM   2953 O O   . TYR A 1 398 ? -69.42500 -1.99100  -3.05600  1.000 49.96981  ? 398 TYR A O   1 
ATOM   2954 C CB  . TYR A 1 398 ? -69.19900 -1.32400  -5.76200  1.000 44.37697  ? 398 TYR A CB  1 
ATOM   2955 C CG  . TYR A 1 398 ? -70.63600 -1.50600  -6.09400  1.000 43.85503  ? 398 TYR A CG  1 
ATOM   2956 C CD1 . TYR A 1 398 ? -71.34500 -0.50500  -6.73200  1.000 49.34077  ? 398 TYR A CD1 1 
ATOM   2957 C CD2 . TYR A 1 398 ? -71.28400 -2.68200  -5.79900  1.000 45.04996  ? 398 TYR A CD2 1 
ATOM   2958 C CE1 . TYR A 1 398 ? -72.66700 -0.66500  -7.05900  1.000 48.80981  ? 398 TYR A CE1 1 
ATOM   2959 C CE2 . TYR A 1 398 ? -72.61100 -2.85800  -6.12400  1.000 47.62409  ? 398 TYR A CE2 1 
ATOM   2960 C CZ  . TYR A 1 398 ? -73.29700 -1.84300  -6.75000  1.000 52.92916  ? 398 TYR A CZ  1 
ATOM   2961 O OH  . TYR A 1 398 ? -74.62200 -2.00500  -7.07600  1.000 60.87266  ? 398 TYR A OH  1 
ATOM   2962 N N   . PRO A 1 399 ? -69.77700 0.12800   -2.43000  1.000 54.97718  ? 399 PRO A N   1 
ATOM   2963 C CA  . PRO A 1 399 ? -70.12800 -0.25900  -1.06200  1.000 56.77233  ? 399 PRO A CA  1 
ATOM   2964 C C   . PRO A 1 399 ? -71.36100 -1.15300  -0.97000  1.000 52.75643  ? 399 PRO A C   1 
ATOM   2965 O O   . PRO A 1 399 ? -71.44500 -1.95700  -0.02700  1.000 53.04675  ? 399 PRO A O   1 
ATOM   2966 C CB  . PRO A 1 399 ? -70.35000 1.09200   -0.36300  1.000 54.70506  ? 399 PRO A CB  1 
ATOM   2967 C CG  . PRO A 1 399 ? -70.43100 2.10900   -1.44600  1.000 52.46127  ? 399 PRO A CG  1 
ATOM   2968 C CD  . PRO A 1 399 ? -69.60000 1.58500   -2.55600  1.000 51.06156  ? 399 PRO A CD  1 
ATOM   2969 N N   . PRO A 1 400 ? -72.34600 -1.06300  -1.88400  1.000 46.50628  ? 400 PRO A N   1 
ATOM   2970 C CA  . PRO A 1 400 ? -73.48400 -2.00600  -1.79300  1.000 48.70422  ? 400 PRO A CA  1 
ATOM   2971 C C   . PRO A 1 400 ? -73.12000 -3.47800  -1.58500  1.000 49.13377  ? 400 PRO A C   1 
ATOM   2972 O O   . PRO A 1 400 ? -73.91700 -4.21500  -0.98700  1.000 48.92609  ? 400 PRO A O   1 
ATOM   2973 C CB  . PRO A 1 400 ? -74.20000 -1.80400  -3.13500  1.000 47.91548  ? 400 PRO A CB  1 
ATOM   2974 C CG  . PRO A 1 400 ? -74.01600 -0.39400  -3.42100  1.000 48.08390  ? 400 PRO A CG  1 
ATOM   2975 C CD  . PRO A 1 400 ? -72.65100 -0.00300  -2.86400  1.000 48.20830  ? 400 PRO A CD  1 
ATOM   2976 N N   . LEU A 1 401 ? -71.95900 -3.93400  -2.06300  1.000 50.31340  ? 401 LEU A N   1 
ATOM   2977 C CA  . LEU A 1 401 ? -71.53000 -5.32200  -1.92200  1.000 42.89967  ? 401 LEU A CA  1 
ATOM   2978 C C   . LEU A 1 401 ? -70.33200 -5.48500  -0.98700  1.000 45.72745  ? 401 LEU A C   1 
ATOM   2979 O O   . LEU A 1 401 ? -69.74100 -6.57100  -0.93300  1.000 47.92582  ? 401 LEU A O   1 
ATOM   2980 C CB  . LEU A 1 401 ? -71.21500 -5.90600  -3.29900  1.000 39.99504  ? 401 LEU A CB  1 
ATOM   2981 C CG  . LEU A 1 401 ? -72.37600 -6.55100  -4.08600  1.000 52.21087  ? 401 LEU A CG  1 
ATOM   2982 C CD1 . LEU A 1 401 ? -72.62400 -8.03000  -3.61800  1.000 52.98229  ? 401 LEU A CD1 1 
ATOM   2983 C CD2 . LEU A 1 401 ? -73.69500 -5.71300  -4.23700  1.000 49.99169  ? 401 LEU A CD2 1 
ATOM   2984 N N   . ALA A 1 402 ? -69.96600 -4.44300  -0.23600  1.000 48.96035  ? 402 ALA A N   1 
ATOM   2985 C CA  . ALA A 1 402 ? -68.85100 -4.57300  0.69700   1.000 40.52623  ? 402 ALA A CA  1 
ATOM   2986 C C   . ALA A 1 402 ? -69.09100 -5.68000  1.71900   1.000 44.71424  ? 402 ALA A C   1 
ATOM   2987 O O   . ALA A 1 402 ? -68.13700 -6.32700  2.16700   1.000 52.15888  ? 402 ALA A O   1 
ATOM   2988 C CB  . ALA A 1 402 ? -68.59900 -3.24000  1.39000   1.000 38.92313  ? 402 ALA A CB  1 
ATOM   2989 N N   . ALA A 1 403 ? -70.35500 -5.93600  2.08500   1.000 49.64414  ? 403 ALA A N   1 
ATOM   2990 C CA  . ALA A 1 403 ? -70.66300 -7.01400  3.03100   1.000 46.41125  ? 403 ALA A CA  1 
ATOM   2991 C C   . ALA A 1 403 ? -70.49500 -8.39800  2.41200   1.000 41.08102  ? 403 ALA A C   1 
ATOM   2992 O O   . ALA A 1 403 ? -70.33400 -9.37600  3.15300   1.000 37.95846  ? 403 ALA A O   1 
ATOM   2993 C CB  . ALA A 1 403 ? -72.09500 -6.87000  3.57200   1.000 47.66166  ? 403 ALA A CB  1 
ATOM   2994 N N   . ARG A 1 404 ? -70.54700 -8.49900  1.08100   1.000 42.65056  ? 404 ARG A N   1 
ATOM   2995 C CA  . ARG A 1 404 ? -70.51300 -9.77500  0.37500   1.000 39.37599  ? 404 ARG A CA  1 
ATOM   2996 C C   . ARG A 1 404 ? -69.10900 -10.13300 -0.09300  1.000 38.99403  ? 404 ARG A C   1 
ATOM   2997 O O   . ARG A 1 404 ? -68.92800 -10.60800 -1.21700  1.000 39.48270  ? 404 ARG A O   1 
ATOM   2998 C CB  . ARG A 1 404 ? -71.47600 -9.76600  -0.80600  1.000 39.94725  ? 404 ARG A CB  1 
ATOM   2999 C CG  . ARG A 1 404 ? -72.91500 -9.32200  -0.51000  1.000 46.19429  ? 404 ARG A CG  1 
ATOM   3000 C CD  . ARG A 1 404 ? -73.53700 -10.06600 0.63800   1.000 49.00535  ? 404 ARG A CD  1 
ATOM   3001 N NE  . ARG A 1 404 ? -73.16500 -11.47400 0.65800   1.000 47.91300  ? 404 ARG A NE  1 
ATOM   3002 C CZ  . ARG A 1 404 ? -73.76100 -12.42300 -0.05100  1.000 51.33665  ? 404 ARG A CZ  1 
ATOM   3003 N NH1 . ARG A 1 404 ? -74.74300 -12.14100 -0.89800  1.000 54.46873  ? 404 ARG A NH1 1 
ATOM   3004 N NH2 . ARG A 1 404 ? -73.35800 -13.68700 0.08800   1.000 47.81554  ? 404 ARG A NH2 1 
ATOM   3005 N N   . ALA A 1 405 ? -68.09200 -9.92600  0.74000   1.000 36.70501  ? 405 ALA A N   1 
ATOM   3006 C CA  . ALA A 1 405 ? -66.79300 -10.51400 0.43000   1.000 34.94706  ? 405 ALA A CA  1 
ATOM   3007 C C   . ALA A 1 405 ? -66.82100 -12.03800 0.46700   1.000 38.66086  ? 405 ALA A C   1 
ATOM   3008 O O   . ALA A 1 405 ? -65.79800 -12.67100 0.15300   1.000 36.48110  ? 405 ALA A O   1 
ATOM   3009 C CB  . ALA A 1 405 ? -65.72300 -9.99500  1.39400   1.000 34.84393  ? 405 ALA A CB  1 
ATOM   3010 N N   . ASP A 1 406 ? -67.95300 -12.64800 0.84200   1.000 36.89498  ? 406 ASP A N   1 
ATOM   3011 C CA  . ASP A 1 406 ? -68.04300 -14.10100 0.82000   1.000 36.08476  ? 406 ASP A CA  1 
ATOM   3012 C C   . ASP A 1 406 ? -68.26600 -14.65300 -0.58700  1.000 34.72066  ? 406 ASP A C   1 
ATOM   3013 O O   . ASP A 1 406 ? -67.97200 -15.82700 -0.83400  1.000 32.04802  ? 406 ASP A O   1 
ATOM   3014 C CB  . ASP A 1 406 ? -69.15000 -14.56400 1.76600   1.000 34.87256  ? 406 ASP A CB  1 
ATOM   3015 C CG  . ASP A 1 406 ? -70.51900 -14.08600 1.33700   1.000 34.56059  ? 406 ASP A CG  1 
ATOM   3016 O OD1 . ASP A 1 406 ? -70.64300 -12.95700 0.82300   1.000 35.08078  ? 406 ASP A OD1 1 
ATOM   3017 O OD2 . ASP A 1 406 ? -71.47900 -14.85200 1.51400   1.000 38.89923  ? 406 ASP A OD2 1 
ATOM   3018 N N   . VAL A 1 407 ? -68.75600 -13.83600 -1.52200  1.000 33.86186  ? 407 VAL A N   1 
ATOM   3019 C CA  . VAL A 1 407 ? -69.01500 -14.31500 -2.87400  1.000 33.04644  ? 407 VAL A CA  1 
ATOM   3020 C C   . VAL A 1 407 ? -68.54500 -13.29400 -3.89700  1.000 30.87895  ? 407 VAL A C   1 
ATOM   3021 O O   . VAL A 1 407 ? -68.46700 -13.60100 -5.08700  1.000 39.77433  ? 407 VAL A O   1 
ATOM   3022 C CB  . VAL A 1 407 ? -70.51100 -14.62800 -3.10200  1.000 40.61045  ? 407 VAL A CB  1 
ATOM   3023 C CG1 . VAL A 1 407 ? -71.04100 -15.60500 -2.05000  1.000 36.26741  ? 407 VAL A CG1 1 
ATOM   3024 C CG2 . VAL A 1 407 ? -71.32800 -13.33900 -3.11200  1.000 34.01144  ? 407 VAL A CG2 1 
ATOM   3025 N N   . ALA A 1 408 ? -68.25700 -12.07000 -3.47800  1.000 34.13604  ? 408 ALA A N   1 
ATOM   3026 C CA  . ALA A 1 408 ? -67.99100 -11.04000 -4.47700  1.000 32.98608  ? 408 ALA A CA  1 
ATOM   3027 C C   . ALA A 1 408 ? -67.02500 -9.98300  -3.94600  1.000 37.32297  ? 408 ALA A C   1 
ATOM   3028 O O   . ALA A 1 408 ? -67.30700 -8.78900  -3.95400  1.000 37.43490  ? 408 ALA A O   1 
ATOM   3029 C CB  . ALA A 1 408 ? -69.29800 -10.40400 -4.94800  1.000 35.19625  ? 408 ALA A CB  1 
ATOM   3030 N N   . ALA A 1 409 ? -65.83800 -10.40700 -3.49500  1.000 34.93320  ? 409 ALA A N   1 
ATOM   3031 C CA  . ALA A 1 409 ? -64.77500 -9.44100  -3.21700  1.000 34.79416  ? 409 ALA A CA  1 
ATOM   3032 C C   . ALA A 1 409 ? -64.07200 -8.99700  -4.49300  1.000 32.72153  ? 409 ALA A C   1 
ATOM   3033 O O   . ALA A 1 409 ? -63.54400 -7.88300  -4.56700  1.000 35.30463  ? 409 ALA A O   1 
ATOM   3034 C CB  . ALA A 1 409 ? -63.75000 -10.03300 -2.24500  1.000 32.83747  ? 409 ALA A CB  1 
ATOM   3035 N N   . GLY A 1 410 ? -64.05600 -9.84200  -5.49200  1.000 35.99760  ? 410 GLY A N   1 
ATOM   3036 C CA  . GLY A 1 410 ? -63.46800 -9.49200  -6.77100  1.000 36.44700  ? 410 GLY A CA  1 
ATOM   3037 C C   . GLY A 1 410 ? -64.46200 -9.74300  -7.87800  1.000 36.14894  ? 410 GLY A C   1 
ATOM   3038 O O   . GLY A 1 410 ? -65.21700 -10.71800 -7.84900  1.000 42.27216  ? 410 GLY A O   1 
ATOM   3039 N N   . ILE A 1 411 ? -64.47600 -8.84200  -8.84100  1.000 38.97732  ? 411 ILE A N   1 
ATOM   3040 C CA  . ILE A 1 411 ? -65.27800 -9.05200  -10.03200 1.000 40.99775  ? 411 ILE A CA  1 
ATOM   3041 C C   . ILE A 1 411 ? -64.39900 -8.78300  -11.23800 1.000 40.67262  ? 411 ILE A C   1 
ATOM   3042 O O   . ILE A 1 411 ? -63.42500 -8.02200  -11.16700 1.000 38.63726  ? 411 ILE A O   1 
ATOM   3043 C CB  . ILE A 1 411 ? -66.54500 -8.18000  -10.05900 1.000 39.33349  ? 411 ILE A CB  1 
ATOM   3044 C CG1 . ILE A 1 411 ? -66.16200 -6.70200  -10.07200 1.000 38.68739  ? 411 ILE A CG1 1 
ATOM   3045 C CG2 . ILE A 1 411 ? -67.46000 -8.53800  -8.86100  1.000 37.20678  ? 411 ILE A CG2 1 
ATOM   3046 C CD1 . ILE A 1 411 ? -67.30300 -5.77000  -10.47200 1.000 41.38166  ? 411 ILE A CD1 1 
ATOM   3047 N N   . LEU A 1 412 ? -64.71800 -9.48300  -12.32700 1.000 41.83273  ? 412 LEU A N   1 
ATOM   3048 C CA  . LEU A 1 412 ? -64.16300 -9.24400  -13.65200 1.000 35.30199  ? 412 LEU A CA  1 
ATOM   3049 C C   . LEU A 1 412 ? -65.33800 -9.25000  -14.62100 1.000 43.12119  ? 412 LEU A C   1 
ATOM   3050 O O   . LEU A 1 412 ? -66.12900 -10.20400 -14.64400 1.000 36.58345  ? 412 LEU A O   1 
ATOM   3051 C CB  . LEU A 1 412 ? -63.11800 -10.30200 -14.00700 1.000 37.16972  ? 412 LEU A CB  1 
ATOM   3052 C CG  . LEU A 1 412 ? -62.74300 -10.59500 -15.46500 1.000 47.91611  ? 412 LEU A CG  1 
ATOM   3053 C CD1 . LEU A 1 412 ? -62.40700 -9.33500  -16.27100 1.000 44.91633  ? 412 LEU A CD1 1 
ATOM   3054 C CD2 . LEU A 1 412 ? -61.57100 -11.57900 -15.49500 1.000 47.04959  ? 412 LEU A CD2 1 
ATOM   3055 N N   . ALA A 1 413 ? -65.46100 -8.17300  -15.40100 1.000 45.95798  ? 413 ALA A N   1 
ATOM   3056 C CA  . ALA A 1 413 ? -66.63600 -7.89700  -16.21500 1.000 42.96054  ? 413 ALA A CA  1 
ATOM   3057 C C   . ALA A 1 413 ? -66.22200 -7.54200  -17.64000 1.000 47.66486  ? 413 ALA A C   1 
ATOM   3058 O O   . ALA A 1 413 ? -65.26500 -6.78900  -17.84400 1.000 44.42909  ? 413 ALA A O   1 
ATOM   3059 C CB  . ALA A 1 413 ? -67.45100 -6.74800  -15.59800 1.000 41.22502  ? 413 ALA A CB  1 
ATOM   3060 N N   . VAL A 1 414 ? -66.94100 -8.08100  -18.63100 1.000 49.11322  ? 414 VAL A N   1 
ATOM   3061 C CA  . VAL A 1 414 ? -66.71500 -7.73300  -20.03300 1.000 50.42624  ? 414 VAL A CA  1 
ATOM   3062 C C   . VAL A 1 414 ? -68.04000 -7.34000  -20.66500 1.000 49.66398  ? 414 VAL A C   1 
ATOM   3063 O O   . VAL A 1 414 ? -69.07600 -7.95400  -20.37900 1.000 46.83813  ? 414 VAL A O   1 
ATOM   3064 C CB  . VAL A 1 414 ? -66.05600 -8.87200  -20.85000 1.000 43.33886  ? 414 VAL A CB  1 
ATOM   3065 C CG1 . VAL A 1 414 ? -64.59100 -9.04700  -20.44800 1.000 48.00112  ? 414 VAL A CG1 1 
ATOM   3066 C CG2 . VAL A 1 414 ? -66.82200 -10.16500 -20.70700 1.000 35.58366  ? 414 VAL A CG2 1 
ATOM   3067 N N   . ARG A 1 415 ? -67.99900 -6.31800  -21.53400 1.000 48.70552  ? 415 ARG A N   1 
ATOM   3068 C CA  . ARG A 1 415 ? -69.16500 -5.91400  -22.31200 1.000 51.00316  ? 415 ARG A CA  1 
ATOM   3069 C C   . ARG A 1 415 ? -69.32500 -6.80400  -23.53200 1.000 52.34822  ? 415 ARG A C   1 
ATOM   3070 O O   . ARG A 1 415 ? -68.40600 -6.92000  -24.34500 1.000 53.89331  ? 415 ARG A O   1 
ATOM   3071 C CB  . ARG A 1 415 ? -69.04200 -4.47800  -22.80100 1.000 59.83870  ? 415 ARG A CB  1 
ATOM   3072 C CG  . ARG A 1 415 ? -68.65800 -3.43600  -21.81400 1.000 57.48319  ? 415 ARG A CG  1 
ATOM   3073 C CD  . ARG A 1 415 ? -68.57900 -2.12200  -22.57100 1.000 61.85183  ? 415 ARG A CD  1 
ATOM   3074 N NE  . ARG A 1 415 ? -68.67100 -0.98200  -21.67600 1.000 62.88464  ? 415 ARG A NE  1 
ATOM   3075 C CZ  . ARG A 1 415 ? -69.81500 -0.55000  -21.17100 1.000 63.68634  ? 415 ARG A CZ  1 
ATOM   3076 N NH1 . ARG A 1 415 ? -70.96700 -1.13100  -21.48100 1.000 59.93978  ? 415 ARG A NH1 1 
ATOM   3077 N NH2 . ARG A 1 415 ? -69.80400 0.48100   -20.32900 1.000 66.43077  ? 415 ARG A NH2 1 
ATOM   3078 N N   . LEU A 1 416 ? -70.50700 -7.39200  -23.68800 1.000 60.91034  ? 416 LEU A N   1 
ATOM   3079 C CA  . LEU A 1 416 ? -70.83200 -8.20800  -24.85000 1.000 57.34347  ? 416 LEU A CA  1 
ATOM   3080 C C   . LEU A 1 416 ? -71.63000 -7.43200  -25.87900 1.000 68.19649  ? 416 LEU A C   1 
ATOM   3081 O O   . LEU A 1 416 ? -72.35600 -8.03500  -26.67700 1.000 75.21436  ? 416 LEU A O   1 
ATOM   3082 C CB  . LEU A 1 416 ? -71.60400 -9.45500  -24.42300 1.000 63.54332  ? 416 LEU A CB  1 
ATOM   3083 C CG  . LEU A 1 416 ? -71.04800 -10.18800 -23.20100 1.000 57.42993  ? 416 LEU A CG  1 
ATOM   3084 C CD1 . LEU A 1 416 ? -71.80600 -11.46200 -23.00000 1.000 46.67049  ? 416 LEU A CD1 1 
ATOM   3085 C CD2 . LEU A 1 416 ? -69.55700 -10.45700 -23.36800 1.000 50.85067  ? 416 LEU A CD2 1 
ATOM   3086 N N   . ALA A 1 417 ? -71.52400 -6.10500  -25.86100 1.000 72.15123  ? 417 ALA A N   1 
ATOM   3087 C CA  . ALA A 1 417 ? -72.26100 -5.20200  -26.73700 1.000 80.56683  ? 417 ALA A CA  1 
ATOM   3088 C C   . ALA A 1 417 ? -71.70100 -3.79700  -26.55000 1.000 85.33647  ? 417 ALA A C   1 
ATOM   3089 O O   . ALA A 1 417 ? -71.16200 -3.48100  -25.47800 1.000 80.77890  ? 417 ALA A O   1 
ATOM   3090 C CB  . ALA A 1 417 ? -73.76500 -5.23600  -26.44300 1.000 77.45474  ? 417 ALA A CB  1 
ATOM   3091 N N   . PRO A 1 418 ? -71.79300 -2.93000  -27.56700 1.000 90.79937  ? 418 PRO A N   1 
ATOM   3092 C CA  . PRO A 1 418 ? -71.19500 -1.59100  -27.45000 1.000 90.47508  ? 418 PRO A CA  1 
ATOM   3093 C C   . PRO A 1 418 ? -71.93900 -0.68600  -26.47800 1.000 93.37865  ? 418 PRO A C   1 
ATOM   3094 O O   . PRO A 1 418 ? -71.68500 -0.71300  -25.26500 1.000 89.20975  ? 418 PRO A O   1 
ATOM   3095 C CB  . PRO A 1 418 ? -71.27300 -1.04800  -28.88400 1.000 90.61513  ? 418 PRO A CB  1 
ATOM   3096 C CG  . PRO A 1 418 ? -71.50800 -2.25300  -29.75100 1.000 85.22446  ? 418 PRO A CG  1 
ATOM   3097 C CD  . PRO A 1 418 ? -72.32100 -3.17700  -28.91800 1.000 85.86401  ? 418 PRO A CD  1 
ATOM   3098 N N   . ALA A 1 419 ? -72.86600 0.13200   -27.01500 1.000 90.95948  ? 419 ALA A N   1 
ATOM   3099 C CA  . ALA A 1 419 ? -73.67400 1.10000   -26.26200 1.000 86.47001  ? 419 ALA A CA  1 
ATOM   3100 C C   . ALA A 1 419 ? -74.72700 0.44500   -25.40500 1.000 93.15061  ? 419 ALA A C   1 
ATOM   3101 O O   . ALA A 1 419 ? -75.55500 1.16000   -24.81300 1.000 96.07358  ? 419 ALA A O   1 
ATOM   3102 C CB  . ALA A 1 419 ? -74.33900 2.09600   -27.21600 1.000 87.35649  ? 419 ALA A CB  1 
ATOM   3103 N N   . ALA A 1 420 ? -74.72400 -0.88100  -25.33100 1.000 94.96013  ? 420 ALA A N   1 
ATOM   3104 C CA  . ALA A 1 420 ? -75.68700 -1.63800  -24.54900 1.000 88.62862  ? 420 ALA A CA  1 
ATOM   3105 C C   . ALA A 1 420 ? -75.05400 -2.12300  -23.24900 1.000 82.78767  ? 420 ALA A C   1 
ATOM   3106 O O   . ALA A 1 420 ? -73.82800 -2.14300  -23.08800 1.000 76.62160  ? 420 ALA A O   1 
ATOM   3107 C CB  . ALA A 1 420 ? -76.22700 -2.82600  -25.35500 1.000 83.09957  ? 420 ALA A CB  1 
ATOM   3108 N N   . ALA A 1 421 ? -75.92100 -2.51100  -22.31600 1.000 81.53193  ? 421 ALA A N   1 
ATOM   3109 C CA  . ALA A 1 421 ? -75.49700 -3.10600  -21.05200 1.000 78.28701  ? 421 ALA A CA  1 
ATOM   3110 C C   . ALA A 1 421 ? -75.67900 -4.62200  -21.12400 1.000 76.92361  ? 421 ALA A C   1 
ATOM   3111 O O   . ALA A 1 421 ? -76.59200 -5.20900  -20.53700 1.000 78.21419  ? 421 ALA A O   1 
ATOM   3112 C CB  . ALA A 1 421 ? -76.27200 -2.49400  -19.88900 1.000 75.86757  ? 421 ALA A CB  1 
ATOM   3113 N N   . ARG A 1 422 ? -74.78700 -5.24400  -21.89400 1.000 74.59316  ? 422 ARG A N   1 
ATOM   3114 C CA  . ARG A 1 422 ? -74.68600 -6.69400  -22.01300 1.000 67.34484  ? 422 ARG A CA  1 
ATOM   3115 C C   . ARG A 1 422 ? -73.33600 -7.10300  -21.44500 1.000 62.05289  ? 422 ARG A C   1 
ATOM   3116 O O   . ARG A 1 422 ? -72.29600 -6.63300  -21.92100 1.000 59.19773  ? 422 ARG A O   1 
ATOM   3117 C CB  . ARG A 1 422 ? -74.82800 -7.13600  -23.46800 1.000 70.36096  ? 422 ARG A CB  1 
ATOM   3118 C CG  . ARG A 1 422 ? -76.16600 -6.78100  -24.09800 1.000 75.18939  ? 422 ARG A CG  1 
ATOM   3119 C CD  . ARG A 1 422 ? -77.21600 -7.85600  -23.81200 1.000 80.18244  ? 422 ARG A CD  1 
ATOM   3120 N NE  . ARG A 1 422 ? -78.50900 -7.52400  -24.40000 1.000 85.39794  ? 422 ARG A NE  1 
ATOM   3121 C CZ  . ARG A 1 422 ? -79.57900 -7.16400  -23.70400 1.000 85.83138  ? 422 ARG A CZ  1 
ATOM   3122 N NH1 . ARG A 1 422 ? -79.56700 -7.14200  -22.37900 1.000 78.19840  ? 422 ARG A NH1 1 
ATOM   3123 N NH2 . ARG A 1 422 ? -80.69200 -6.82500  -24.35400 1.000 82.37915  ? 422 ARG A NH2 1 
ATOM   3124 N N   . PHE A 1 423 ? -73.35200 -7.96100  -20.42400 1.000 65.73371  ? 423 PHE A N   1 
ATOM   3125 C CA  . PHE A 1 423 ? -72.15800 -8.22500  -19.63200 1.000 55.51078  ? 423 PHE A CA  1 
ATOM   3126 C C   . PHE A 1 423 ? -72.02200 -9.70200  -19.30100 1.000 53.66165  ? 423 PHE A C   1 
ATOM   3127 O O   . PHE A 1 423 ? -73.00900 -10.43500 -19.20200 1.000 55.46557  ? 423 PHE A O   1 
ATOM   3128 C CB  . PHE A 1 423 ? -72.16200 -7.44600  -18.31400 1.000 55.70336  ? 423 PHE A CB  1 
ATOM   3129 C CG  . PHE A 1 423 ? -71.99500 -5.97200  -18.47600 1.000 59.98195  ? 423 PHE A CG  1 
ATOM   3130 C CD1 . PHE A 1 423 ? -70.73500 -5.41800  -18.62300 1.000 57.25495  ? 423 PHE A CD1 1 
ATOM   3131 C CD2 . PHE A 1 423 ? -73.09800 -5.13200  -18.46500 1.000 64.99859  ? 423 PHE A CD2 1 
ATOM   3132 C CE1 . PHE A 1 423 ? -70.57700 -4.05200  -18.77000 1.000 56.57323  ? 423 PHE A CE1 1 
ATOM   3133 C CE2 . PHE A 1 423 ? -72.95000 -3.76900  -18.61300 1.000 62.19133  ? 423 PHE A CE2 1 
ATOM   3134 C CZ  . PHE A 1 423 ? -71.68600 -3.22700  -18.76700 1.000 62.98695  ? 423 PHE A CZ  1 
ATOM   3135 N N   . ALA A 1 424 ? -70.76900 -10.12200 -19.13300 1.000 53.70330  ? 424 ALA A N   1 
ATOM   3136 C CA  . ALA A 1 424 ? -70.41200 -11.33400 -18.40900 1.000 48.05049  ? 424 ALA A CA  1 
ATOM   3137 C C   . ALA A 1 424 ? -69.56700 -10.89200 -17.22800 1.000 47.64573  ? 424 ALA A C   1 
ATOM   3138 O O   . ALA A 1 424 ? -68.55300 -10.20500 -17.41000 1.000 48.72431  ? 424 ALA A O   1 
ATOM   3139 C CB  . ALA A 1 424 ? -69.64300 -12.32100 -19.28600 1.000 47.25537  ? 424 ALA A CB  1 
ATOM   3140 N N   . ILE A 1 425 ? -70.00500 -11.24500 -16.02300 1.000 43.44627  ? 425 ILE A N   1 
ATOM   3141 C CA  . ILE A 1 425 ? -69.32200 -10.85500 -14.79500 1.000 41.30120  ? 425 ILE A CA  1 
ATOM   3142 C C   . ILE A 1 425 ? -68.94800 -12.12100 -14.04700 1.000 42.02597  ? 425 ILE A C   1 
ATOM   3143 O O   . ILE A 1 425 ? -69.82300 -12.94800 -13.75200 1.000 37.38936  ? 425 ILE A O   1 
ATOM   3144 C CB  . ILE A 1 425 ? -70.19200 -9.94500  -13.91700 1.000 42.53811  ? 425 ILE A CB  1 
ATOM   3145 C CG1 . ILE A 1 425 ? -70.66800 -8.73000  -14.72500 1.000 47.66324  ? 425 ILE A CG1 1 
ATOM   3146 C CG2 . ILE A 1 425 ? -69.42000 -9.51800  -12.67200 1.000 39.39294  ? 425 ILE A CG2 1 
ATOM   3147 C CD1 . ILE A 1 425 ? -72.03300 -8.21900  -14.31200 1.000 39.87076  ? 425 ILE A CD1 1 
ATOM   3148 N N   . TRP A 1 426 ? -67.65100 -12.28000 -13.76200 1.000 40.04623  ? 426 TRP A N   1 
ATOM   3149 C CA  . TRP A 1 426 ? -67.14400 -13.36600 -12.93400 1.000 34.20576  ? 426 TRP A CA  1 
ATOM   3150 C C   . TRP A 1 426 ? -66.91000 -12.85100 -11.52900 1.000 33.89823  ? 426 TRP A C   1 
ATOM   3151 O O   . TRP A 1 426 ? -66.41600 -11.73800 -11.35200 1.000 40.49002  ? 426 TRP A O   1 
ATOM   3152 C CB  . TRP A 1 426 ? -65.84100 -13.92800 -13.49600 1.000 35.18816  ? 426 TRP A CB  1 
ATOM   3153 C CG  . TRP A 1 426 ? -66.01700 -14.70000 -14.75100 1.000 34.93933  ? 426 TRP A CG  1 
ATOM   3154 C CD1 . TRP A 1 426 ? -66.25800 -16.03300 -14.86500 1.000 33.24533  ? 426 TRP A CD1 1 
ATOM   3155 C CD2 . TRP A 1 426 ? -65.98800 -14.18100 -16.08800 1.000 38.15071  ? 426 TRP A CD2 1 
ATOM   3156 N NE1 . TRP A 1 426 ? -66.36100 -16.39100 -16.19300 1.000 32.95450  ? 426 TRP A NE1 1 
ATOM   3157 C CE2 . TRP A 1 426 ? -66.19800 -15.27000 -16.96500 1.000 37.04830  ? 426 TRP A CE2 1 
ATOM   3158 C CE3 . TRP A 1 426 ? -65.79100 -12.90500 -16.63000 1.000 39.85659  ? 426 TRP A CE3 1 
ATOM   3159 C CZ2 . TRP A 1 426 ? -66.21800 -15.12300 -18.35800 1.000 36.41424  ? 426 TRP A CZ2 1 
ATOM   3160 C CZ3 . TRP A 1 426 ? -65.80500 -12.76200 -18.01400 1.000 39.28055  ? 426 TRP A CZ3 1 
ATOM   3161 C CH2 . TRP A 1 426 ? -66.02300 -13.87100 -18.86100 1.000 37.47094  ? 426 TRP A CH2 1 
ATOM   3162 N N   . PHE A 1 427 ? -67.26100 -13.65600 -10.53100 1.000 34.57531  ? 427 PHE A N   1 
ATOM   3163 C CA  . PHE A 1 427 ? -67.08300 -13.28700 -9.13400  1.000 34.88990  ? 427 PHE A CA  1 
ATOM   3164 C C   . PHE A 1 427 ? -65.99700 -14.13100 -8.48500  1.000 33.40599  ? 427 PHE A C   1 
ATOM   3165 O O   . PHE A 1 427 ? -65.83200 -15.31700 -8.79400  1.000 32.15965  ? 427 PHE A O   1 
ATOM   3166 C CB  . PHE A 1 427 ? -68.37700 -13.45900 -8.33200  1.000 37.85054  ? 427 PHE A CB  1 
ATOM   3167 C CG  . PHE A 1 427 ? -69.48800 -12.61200 -8.82000  1.000 40.32682  ? 427 PHE A CG  1 
ATOM   3168 C CD1 . PHE A 1 427 ? -69.59000 -11.29400 -8.41400  1.000 40.61945  ? 427 PHE A CD1 1 
ATOM   3169 C CD2 . PHE A 1 427 ? -70.41500 -13.11800 -9.71800  1.000 39.94620  ? 427 PHE A CD2 1 
ATOM   3170 C CE1 . PHE A 1 427 ? -70.60400 -10.49100 -8.88500  1.000 40.76115  ? 427 PHE A CE1 1 
ATOM   3171 C CE2 . PHE A 1 427 ? -71.43700 -12.32200 -10.19100 1.000 36.93763  ? 427 PHE A CE2 1 
ATOM   3172 C CZ  . PHE A 1 427 ? -71.53000 -11.00500 -9.77600  1.000 40.30656  ? 427 PHE A CZ  1 
ATOM   3173 N N   . ARG A 1 428 ? -65.27200 -13.51000 -7.56400  1.000 31.98216  ? 428 ARG A N   1 
ATOM   3174 C CA  . ARG A 1 428 ? -64.38400 -14.26800 -6.70600  1.000 34.86407  ? 428 ARG A CA  1 
ATOM   3175 C C   . ARG A 1 428 ? -64.69200 -13.97300 -5.24700  1.000 36.00940  ? 428 ARG A C   1 
ATOM   3176 O O   . ARG A 1 428 ? -65.18000 -12.88200 -4.91400  1.000 32.54877  ? 428 ARG A O   1 
ATOM   3177 C CB  . ARG A 1 428 ? -62.91500 -13.93900 -6.98400  1.000 31.45375  ? 428 ARG A CB  1 
ATOM   3178 C CG  . ARG A 1 428 ? -62.39100 -14.56100 -8.21100  1.000 30.29212  ? 428 ARG A CG  1 
ATOM   3179 C CD  . ARG A 1 428 ? -60.91500 -14.26200 -8.28500  1.000 34.94388  ? 428 ARG A CD  1 
ATOM   3180 N NE  . ARG A 1 428 ? -60.31000 -14.88800 -9.45100  1.000 35.35350  ? 428 ARG A NE  1 
ATOM   3181 C CZ  . ARG A 1 428 ? -59.06600 -14.66400 -9.85300  1.000 38.08377  ? 428 ARG A CZ  1 
ATOM   3182 N NH1 . ARG A 1 428 ? -58.25200 -13.85400 -9.17900  1.000 34.14076  ? 428 ARG A NH1 1 
ATOM   3183 N NH2 . ARG A 1 428 ? -58.63400 -15.25100 -10.96300 1.000 30.85547  ? 428 ARG A NH2 1 
ATOM   3184 N N   . PRO A 1 429 ? -64.41600 -14.92800 -4.35900  1.000 33.62051  ? 429 PRO A N   1 
ATOM   3185 C CA  . PRO A 1 429 ? -64.51200 -14.66300 -2.92300  1.000 33.24327  ? 429 PRO A CA  1 
ATOM   3186 C C   . PRO A 1 429 ? -63.22500 -14.07400 -2.36600  1.000 36.47485  ? 429 PRO A C   1 
ATOM   3187 O O   . PRO A 1 429 ? -62.13800 -14.21200 -2.93400  1.000 38.97483  ? 429 PRO A O   1 
ATOM   3188 C CB  . PRO A 1 429 ? -64.75900 -16.05600 -2.32900  1.000 33.60963  ? 429 PRO A CB  1 
ATOM   3189 C CG  . PRO A 1 429 ? -64.00000 -16.96500 -3.25100  1.000 32.30801  ? 429 PRO A CG  1 
ATOM   3190 C CD  . PRO A 1 429 ? -64.12000 -16.35200 -4.63700  1.000 31.26028  ? 429 PRO A CD  1 
ATOM   3191 N N   . GLU A 1 430 ? -63.36500 -13.44500 -1.20400  1.000 31.05266  ? 430 GLU A N   1 
ATOM   3192 C CA  . GLU A 1 430 ? -62.19900 -13.01700 -0.45600  1.000 36.92125  ? 430 GLU A CA  1 
ATOM   3193 C C   . GLU A 1 430 ? -61.28200 -14.20600 -0.20000  1.000 35.04754  ? 430 GLU A C   1 
ATOM   3194 O O   . GLU A 1 430 ? -61.72200 -15.35400 -0.09400  1.000 36.18622  ? 430 GLU A O   1 
ATOM   3195 C CB  . GLU A 1 430 ? -62.62100 -12.36200 0.87300   1.000 35.18707  ? 430 GLU A CB  1 
ATOM   3196 C CG  . GLU A 1 430 ? -62.56000 -13.26100 2.09600   1.000 34.64503  ? 430 GLU A CG  1 
ATOM   3197 C CD  . GLU A 1 430 ? -62.95600 -12.53500 3.37700   1.000 40.64332  ? 430 GLU A CD  1 
ATOM   3198 O OE1 . GLU A 1 430 ? -62.14100 -11.73300 3.90200   1.000 39.39262  ? 430 GLU A OE1 1 
ATOM   3199 O OE2 . GLU A 1 430 ? -64.09200 -12.75700 3.86300   1.000 39.10171  ? 430 GLU A OE2 1 
ATOM   3200 N N   . VAL A 1 431 ? -59.98800 -13.92700 -0.14400  1.000 37.59519  ? 431 VAL A N   1 
ATOM   3201 C CA  . VAL A 1 431 ? -58.98500 -14.88800 0.29100   1.000 38.95874  ? 431 VAL A CA  1 
ATOM   3202 C C   . VAL A 1 431 ? -58.18100 -14.16300 1.35300   1.000 36.52408  ? 431 VAL A C   1 
ATOM   3203 O O   . VAL A 1 431 ? -57.46900 -13.20100 1.04200   1.000 41.97029  ? 431 VAL A O   1 
ATOM   3204 C CB  . VAL A 1 431 ? -58.08500 -15.37100 -0.86000  1.000 39.45013  ? 431 VAL A CB  1 
ATOM   3205 C CG1 . VAL A 1 431 ? -56.88300 -16.15300 -0.33600  1.000 40.45099  ? 431 VAL A CG1 1 
ATOM   3206 C CG2 . VAL A 1 431 ? -58.86500 -16.26900 -1.77300  1.000 39.22773  ? 431 VAL A CG2 1 
ATOM   3207 N N   . ALA A 1 432 ? -58.33600 -14.57600 2.60600   1.000 35.46080  ? 432 ALA A N   1 
ATOM   3208 C CA  . ALA A 1 432 ? -57.64000 -13.91700 3.70300   1.000 39.64993  ? 432 ALA A CA  1 
ATOM   3209 C C   . ALA A 1 432 ? -56.17000 -14.30800 3.70900   1.000 41.55015  ? 432 ALA A C   1 
ATOM   3210 O O   . ALA A 1 432 ? -55.80100 -15.42500 3.33800   1.000 46.21042  ? 432 ALA A O   1 
ATOM   3211 C CB  . ALA A 1 432 ? -58.27600 -14.26500 5.04600   1.000 38.16423  ? 432 ALA A CB  1 
ATOM   3212 N N   . ARG A 1 433 ? -55.33100 -13.36500 4.13400   1.000 50.40839  ? 433 ARG A N   1 
ATOM   3213 C CA  . ARG A 1 433 ? -53.88000 -13.47500 4.05500   1.000 44.29507  ? 433 ARG A CA  1 
ATOM   3214 C C   . ARG A 1 433 ? -53.26800 -12.92000 5.32600   1.000 38.09601  ? 433 ARG A C   1 
ATOM   3215 O O   . ARG A 1 433 ? -53.71000 -11.88600 5.82600   1.000 45.61548  ? 433 ARG A O   1 
ATOM   3216 C CB  . ARG A 1 433 ? -53.33600 -12.70600 2.84300   1.000 44.25911  ? 433 ARG A CB  1 
ATOM   3217 C CG  . ARG A 1 433 ? -53.46900 -13.45000 1.52900   1.000 52.98860  ? 433 ARG A CG  1 
ATOM   3218 C CD  . ARG A 1 433 ? -53.69300 -12.48900 0.37800   1.000 57.22573  ? 433 ARG A CD  1 
ATOM   3219 N NE  . ARG A 1 433 ? -55.10600 -12.39000 0.03600   1.000 53.53411  ? 433 ARG A NE  1 
ATOM   3220 C CZ  . ARG A 1 433 ? -55.57300 -11.88500 -1.10100  1.000 53.35479  ? 433 ARG A CZ  1 
ATOM   3221 N NH1 . ARG A 1 433 ? -54.75900 -11.39600 -2.03000  1.000 51.21252  ? 433 ARG A NH1 1 
ATOM   3222 N NH2 . ARG A 1 433 ? -56.88900 -11.88500 -1.31900  1.000 45.73156  ? 433 ARG A NH2 1 
ATOM   3223 N N   . THR A 1 434 ? -52.24500 -13.59000 5.83700   1.000 51.02964  ? 434 THR A N   1 
ATOM   3224 C CA  . THR A 1 434 ? -51.54100 -13.14700 7.04200   1.000 52.34581  ? 434 THR A CA  1 
ATOM   3225 C C   . THR A 1 434 ? -50.15900 -12.62300 6.65100   1.000 53.07340  ? 434 THR A C   1 
ATOM   3226 O O   . THR A 1 434 ? -49.22500 -13.39600 6.40000   1.000 51.89141  ? 434 THR A O   1 
ATOM   3227 C CB  . THR A 1 434 ? -51.45000 -14.26900 8.07200   1.000 49.48311  ? 434 THR A CB  1 
ATOM   3228 O OG1 . THR A 1 434 ? -52.74700 -14.49000 8.63400   1.000 48.81540  ? 434 THR A OG1 1 
ATOM   3229 C CG2 . THR A 1 434 ? -50.51700 -13.87600 9.19500   1.000 53.61840  ? 434 THR A CG2 1 
ATOM   3230 N N   . ILE A 1 435 ? -50.04900 -11.29800 6.60400   1.000 55.15521  ? 435 ILE A N   1 
ATOM   3231 C CA  . ILE A 1 435 ? -48.77800 -10.60800 6.42300   1.000 53.41150  ? 435 ILE A CA  1 
ATOM   3232 C C   . ILE A 1 435 ? -48.07100 -10.49100 7.76600   1.000 47.67025  ? 435 ILE A C   1 
ATOM   3233 O O   . ILE A 1 435 ? -48.69300 -10.17600 8.78800   1.000 47.35922  ? 435 ILE A O   1 
ATOM   3234 C CB  . ILE A 1 435 ? -49.01600 -9.21800  5.81600   1.000 47.87586  ? 435 ILE A CB  1 
ATOM   3235 C CG1 . ILE A 1 435 ? -49.64000 -9.34000  4.43200   1.000 52.28103  ? 435 ILE A CG1 1 
ATOM   3236 C CG2 . ILE A 1 435 ? -47.72000 -8.43100  5.74600   1.000 51.56909  ? 435 ILE A CG2 1 
ATOM   3237 C CD1 . ILE A 1 435 ? -49.85600 -7.99300  3.76700   1.000 54.35319  ? 435 ILE A CD1 1 
ATOM   3238 N N   . SER A 1 436 ? -46.76400 -10.72400 7.76900   1.000 44.61752  ? 436 SER A N   1 
ATOM   3239 C CA  . SER A 1 436 ? -45.93200 -10.46500 8.94100   1.000 46.69150  ? 436 SER A CA  1 
ATOM   3240 C C   . SER A 1 436 ? -44.99000 -9.31000  8.60400   1.000 46.01607  ? 436 SER A C   1 
ATOM   3241 O O   . SER A 1 436 ? -44.01900 -9.48300  7.86200   1.000 48.98445  ? 436 SER A O   1 
ATOM   3242 C CB  . SER A 1 436 ? -45.17200 -11.71700 9.34700   1.000 48.37208  ? 436 SER A CB  1 
ATOM   3243 O OG  . SER A 1 436 ? -45.99400 -12.85500 9.14100   1.000 65.14954  ? 436 SER A OG  1 
ATOM   3244 N N   . TRP A 1 437 ? -45.28500 -8.12900  9.13800   1.000 43.96394  ? 437 TRP A N   1 
ATOM   3245 C CA  . TRP A 1 437 ? -44.40000 -6.99100  8.96200   1.000 42.56311  ? 437 TRP A CA  1 
ATOM   3246 C C   . TRP A 1 437 ? -43.23800 -7.05900  9.94100   1.000 41.33398  ? 437 TRP A C   1 
ATOM   3247 O O   . TRP A 1 437 ? -43.37800 -7.55000  11.06400  1.000 41.10392  ? 437 TRP A O   1 
ATOM   3248 C CB  . TRP A 1 437 ? -45.15300 -5.68700  9.16300   1.000 41.30715  ? 437 TRP A CB  1 
ATOM   3249 C CG  . TRP A 1 437 ? -46.18800 -5.47000  8.15600   1.000 41.52248  ? 437 TRP A CG  1 
ATOM   3250 C CD1 . TRP A 1 437 ? -47.46900 -5.90900  8.20400   1.000 44.91457  ? 437 TRP A CD1 1 
ATOM   3251 C CD2 . TRP A 1 437 ? -46.04800 -4.75500  6.93700   1.000 39.05151  ? 437 TRP A CD2 1 
ATOM   3252 N NE1 . TRP A 1 437 ? -48.14800 -5.50800  7.09000   1.000 44.54072  ? 437 TRP A NE1 1 
ATOM   3253 C CE2 . TRP A 1 437 ? -47.29600 -4.79800  6.28600   1.000 46.99385  ? 437 TRP A CE2 1 
ATOM   3254 C CE3 . TRP A 1 437 ? -44.98600 -4.07600  6.32800   1.000 42.11040  ? 437 TRP A CE3 1 
ATOM   3255 C CZ2 . TRP A 1 437 ? -47.52400 -4.17900  5.04300   1.000 43.97692  ? 437 TRP A CZ2 1 
ATOM   3256 C CZ3 . TRP A 1 437 ? -45.20400 -3.46500  5.09300   1.000 40.66301  ? 437 TRP A CZ3 1 
ATOM   3257 C CH2 . TRP A 1 437 ? -46.46700 -3.52400  4.46500   1.000 43.46797  ? 437 TRP A CH2 1 
ATOM   3258 N N   . ALA A 1 438 ? -42.08100 -6.55500  9.49600   1.000 42.08598  ? 438 ALA A N   1 
ATOM   3259 C CA  . ALA A 1 438 ? -40.87800 -6.43500  10.32900  1.000 40.02280  ? 438 ALA A CA  1 
ATOM   3260 C C   . ALA A 1 438 ? -40.98500 -5.14900  11.14700  1.000 44.97187  ? 438 ALA A C   1 
ATOM   3261 O O   . ALA A 1 438 ? -40.33200 -4.13400  10.87400  1.000 41.72705  ? 438 ALA A O   1 
ATOM   3262 C CB  . ALA A 1 438 ? -39.62500 -6.44400  9.46500   1.000 39.16332  ? 438 ALA A CB  1 
ATOM   3263 N N   . GLY A 1 439 ? -41.84100 -5.19900  12.17100  1.000 40.14015  ? 439 GLY A N   1 
ATOM   3264 C CA  . GLY A 1 439 ? -42.20800 -4.01400  12.92000  1.000 36.99861  ? 439 GLY A CA  1 
ATOM   3265 C C   . GLY A 1 439 ? -43.61200 -3.53900  12.58300  1.000 46.17356  ? 439 GLY A C   1 
ATOM   3266 O O   . GLY A 1 439 ? -44.29900 -4.06200  11.70300  1.000 48.32130  ? 439 GLY A O   1 
ATOM   3267 N N   . ASN A 1 440 ? -44.04600 -2.52600  13.31800  1.000 51.54296  ? 440 ASN A N   1 
ATOM   3268 C CA  . ASN A 1 440 ? -45.36500 -1.94000  13.13400  1.000 49.03874  ? 440 ASN A CA  1 
ATOM   3269 C C   . ASN A 1 440 ? -45.34000 -1.06200  11.89200  1.000 51.39872  ? 440 ASN A C   1 
ATOM   3270 O O   . ASN A 1 440 ? -44.60700 -0.06800  11.85800  1.000 56.20508  ? 440 ASN A O   1 
ATOM   3271 C CB  . ASN A 1 440 ? -45.75700 -1.12900  14.37100  1.000 49.89771  ? 440 ASN A CB  1 
ATOM   3272 C CG  . ASN A 1 440 ? -47.23500 -0.79200  14.41100  1.000 54.84664  ? 440 ASN A CG  1 
ATOM   3273 O OD1 . ASN A 1 440 ? -47.85300 -0.49000  13.39000  1.000 55.81269  ? 440 ASN A OD1 1 
ATOM   3274 N ND2 . ASN A 1 440 ? -47.80900 -0.83600  15.60400  1.000 66.85806  ? 440 ASN A ND2 1 
ATOM   3275 N N   . PRO A 1 441 ? -46.11300 -1.38800  10.84900  1.000 53.90426  ? 441 PRO A N   1 
ATOM   3276 C CA  . PRO A 1 441 ? -46.07000 -0.57400  9.61900   1.000 48.55076  ? 441 PRO A CA  1 
ATOM   3277 C C   . PRO A 1 441 ? -46.79200 0.74900   9.74000   1.000 51.05498  ? 441 PRO A C   1 
ATOM   3278 O O   . PRO A 1 441 ? -46.70700 1.56600   8.81300   1.000 55.59158  ? 441 PRO A O   1 
ATOM   3279 C CB  . PRO A 1 441 ? -46.74400 -1.47500  8.58200   1.000 44.48347  ? 441 PRO A CB  1 
ATOM   3280 C CG  . PRO A 1 441 ? -47.69700 -2.28700  9.39400   1.000 49.95488  ? 441 PRO A CG  1 
ATOM   3281 C CD  . PRO A 1 441 ? -47.01400 -2.54400  10.71500  1.000 45.93326  ? 441 PRO A CD  1 
ATOM   3282 N N   . ARG A 1 442 ? -47.50400 0.98500   10.84000  1.000 51.29560  ? 442 ARG A N   1 
ATOM   3283 C CA  . ARG A 1 442 ? -48.14800 2.27400   11.05400  1.000 56.69806  ? 442 ARG A CA  1 
ATOM   3284 C C   . ARG A 1 442 ? -47.19600 3.31200   11.63000  1.000 54.16646  ? 442 ARG A C   1 
ATOM   3285 O O   . ARG A 1 442 ? -47.36800 4.50500   11.35800  1.000 56.45804  ? 442 ARG A O   1 
ATOM   3286 C CB  . ARG A 1 442 ? -49.35400 2.12000   11.98300  1.000 62.72667  ? 442 ARG A CB  1 
ATOM   3287 C CG  . ARG A 1 442 ? -50.35500 1.06300   11.55100  1.000 57.39767  ? 442 ARG A CG  1 
ATOM   3288 C CD  . ARG A 1 442 ? -51.51500 1.05100   12.52100  1.000 77.29424  ? 442 ARG A CD  1 
ATOM   3289 N NE  . ARG A 1 442 ? -52.10000 -0.27300  12.70600  1.000 86.86863  ? 442 ARG A NE  1 
ATOM   3290 C CZ  . ARG A 1 442 ? -53.10900 -0.75900  11.99300  1.000 89.41616  ? 442 ARG A CZ  1 
ATOM   3291 N NH1 . ARG A 1 442 ? -53.62600 -0.08400  10.97600  1.000 84.35247  ? 442 ARG A NH1 1 
ATOM   3292 N NH2 . ARG A 1 442 ? -53.61500 -1.94800  12.31300  1.000 81.77252  ? 442 ARG A NH2 1 
ATOM   3293 N N   . LYS A 1 443 ? -46.19100 2.88100   12.41900  1.000 57.41589  ? 443 LYS A N   1 
ATOM   3294 C CA  . LYS A 1 443 ? -45.09300 3.72800   12.89300  1.000 56.55472  ? 443 LYS A CA  1 
ATOM   3295 C C   . LYS A 1 443 ? -43.75900 3.28800   12.28700  1.000 49.64486  ? 443 LYS A C   1 
ATOM   3296 O O   . LYS A 1 443 ? -42.89300 2.76300   13.00200  1.000 49.77500  ? 443 LYS A O   1 
ATOM   3297 C CB  . LYS A 1 443 ? -45.00900 3.69900   14.42700  1.000 60.45168  ? 443 LYS A CB  1 
ATOM   3298 C CG  . LYS A 1 443 ? -45.99400 4.64100   15.16700  1.000 66.16465  ? 443 LYS A CG  1 
ATOM   3299 C CD  . LYS A 1 443 ? -45.30900 5.94600   15.62700  1.000 74.26812  ? 443 LYS A CD  1 
ATOM   3300 C CE  . LYS A 1 443 ? -46.15200 6.72900   16.65500  1.000 78.85742  ? 443 LYS A CE  1 
ATOM   3301 N NZ  . LYS A 1 443 ? -45.48200 7.98900   17.13800  1.000 70.27406  ? 443 LYS A NZ  1 
ATOM   3302 N N   . PRO A 1 444 ? -43.54100 3.49400   10.98700  1.000 50.38158  ? 444 PRO A N   1 
ATOM   3303 C CA  . PRO A 1 444 ? -42.32200 2.99300   10.34000  1.000 42.70159  ? 444 PRO A CA  1 
ATOM   3304 C C   . PRO A 1 444 ? -41.08900 3.86300   10.54200  1.000 45.28084  ? 444 PRO A C   1 
ATOM   3305 O O   . PRO A 1 444 ? -40.09800 3.66900   9.82700   1.000 41.13578  ? 444 PRO A O   1 
ATOM   3306 C CB  . PRO A 1 444 ? -42.73100 2.97700   8.86200   1.000 46.99104  ? 444 PRO A CB  1 
ATOM   3307 C CG  . PRO A 1 444 ? -43.64600 4.17000   8.74000   1.000 44.89780  ? 444 PRO A CG  1 
ATOM   3308 C CD  . PRO A 1 444 ? -44.40000 4.23800   10.04200  1.000 48.87215  ? 444 PRO A CD  1 
ATOM   3309 N N   . ALA A 1 445 ? -41.14200 4.81100   11.47900  1.000 47.11054  ? 445 ALA A N   1 
ATOM   3310 C CA  . ALA A 1 445 ? -40.09800 5.78800   11.76700  1.000 46.11757  ? 445 ALA A CA  1 
ATOM   3311 C C   . ALA A 1 445 ? -40.43100 6.46300   13.08500  1.000 45.98602  ? 445 ALA A C   1 
ATOM   3312 O O   . ALA A 1 445 ? -41.60400 6.62400   13.42900  1.000 49.51057  ? 445 ALA A O   1 
ATOM   3313 C CB  . ALA A 1 445 ? -39.97800 6.84300   10.66200  1.000 40.39289  ? 445 ALA A CB  1 
ATOM   3314 N N   . GLU A 1 446 ? -39.39300 6.85100   13.81900  1.000 47.35927  ? 446 GLU A N   1 
ATOM   3315 C CA  . GLU A 1 446 ? -39.58500 7.60300   15.05600  1.000 51.11981  ? 446 GLU A CA  1 
ATOM   3316 C C   . GLU A 1 446 ? -39.14900 9.04800   14.85300  1.000 51.19937  ? 446 GLU A C   1 
ATOM   3317 O O   . GLU A 1 446 ? -37.95100 9.35600   14.95100  1.000 50.54573  ? 446 GLU A O   1 
ATOM   3318 C CB  . GLU A 1 446 ? -38.81500 6.96300   16.21400  1.000 46.95668  ? 446 GLU A CB  1 
ATOM   3319 C CG  . GLU A 1 446 ? -39.72300 6.40300   17.31900  1.000 54.50071  ? 446 GLU A CG  1 
ATOM   3320 C CD  . GLU A 1 446 ? -39.51700 4.91200   17.53800  1.000 61.31366  ? 446 GLU A CD  1 
ATOM   3321 O OE1 . GLU A 1 446 ? -38.39900 4.51200   17.94300  1.000 55.87811  ? 446 GLU A OE1 1 
ATOM   3322 O OE2 . GLU A 1 446 ? -40.47000 4.13800   17.28700  1.000 62.47515  ? 446 GLU A OE2 1 
ATOM   3323 N N   . PRO A 1 447 ? -40.06800 9.96400   14.56100  1.000 49.29442  ? 447 PRO A N   1 
ATOM   3324 C CA  . PRO A 1 447 ? -39.69400 11.37600  14.44400  1.000 54.85004  ? 447 PRO A CA  1 
ATOM   3325 C C   . PRO A 1 447 ? -39.51600 12.02200  15.81300  1.000 50.88461  ? 447 PRO A C   1 
ATOM   3326 O O   . PRO A 1 447 ? -40.15500 11.63900  16.79600  1.000 53.28757  ? 447 PRO A O   1 
ATOM   3327 C CB  . PRO A 1 447 ? -40.88400 11.99100  13.69200  1.000 58.63854  ? 447 PRO A CB  1 
ATOM   3328 C CG  . PRO A 1 447 ? -42.07100 11.13800  14.10500  1.000 55.54915  ? 447 PRO A CG  1 
ATOM   3329 C CD  . PRO A 1 447 ? -41.51900 9.74300   14.38800  1.000 53.74205  ? 447 PRO A CD  1 
ATOM   3330 N N   . GLU A 1 448 ? -38.62500 13.01700  15.86800  1.000 48.66991  ? 448 GLU A N   1 
ATOM   3331 C CA  . GLU A 1 448 ? -38.44200 13.79400  17.08200  1.000 42.97694  ? 448 GLU A CA  1 
ATOM   3332 C C   . GLU A 1 448 ? -39.50400 14.88800  17.17600  1.000 44.53085  ? 448 GLU A C   1 
ATOM   3333 O O   . GLU A 1 448 ? -40.14500 15.22400  16.17600  1.000 47.95924  ? 448 GLU A O   1 
ATOM   3334 C CB  . GLU A 1 448 ? -37.04500 14.40800  17.10800  1.000 46.67482  ? 448 GLU A CB  1 
ATOM   3335 C CG  . GLU A 1 448 ? -35.91300 13.43700  17.44300  1.000 44.95722  ? 448 GLU A CG  1 
ATOM   3336 C CD  . GLU A 1 448 ? -34.54700 14.11400  17.43200  1.000 50.54292  ? 448 GLU A CD  1 
ATOM   3337 O OE1 . GLU A 1 448 ? -34.50600 15.36600  17.45900  1.000 50.50166  ? 448 GLU A OE1 1 
ATOM   3338 O OE2 . GLU A 1 448 ? -33.51600 13.40200  17.38500  1.000 47.07301  ? 448 GLU A OE2 1 
ATOM   3339 N N   . PRO A 1 449 ? -39.74800 15.42200  18.38100  1.000 48.90550  ? 449 PRO A N   1 
ATOM   3340 C CA  . PRO A 1 449 ? -40.60800 16.60700  18.51000  1.000 42.76776  ? 449 PRO A CA  1 
ATOM   3341 C C   . PRO A 1 449 ? -40.27500 17.68300  17.48700  1.000 41.66313  ? 449 PRO A C   1 
ATOM   3342 O O   . PRO A 1 449 ? -39.10700 17.95300  17.19500  1.000 38.81671  ? 449 PRO A O   1 
ATOM   3343 C CB  . PRO A 1 449 ? -40.33000 17.07700  19.93900  1.000 41.40761  ? 449 PRO A CB  1 
ATOM   3344 C CG  . PRO A 1 449 ? -40.15200 15.78300  20.68100  1.000 44.79781  ? 449 PRO A CG  1 
ATOM   3345 C CD  . PRO A 1 449 ? -39.47800 14.81500  19.70300  1.000 44.23503  ? 449 PRO A CD  1 
ATOM   3346 N N   . GLY A 1 450 ? -41.32600 18.29000  16.93100  1.000 45.07672  ? 450 GLY A N   1 
ATOM   3347 C CA  . GLY A 1 450 ? -41.17700 19.28100  15.88700  1.000 44.99533  ? 450 GLY A CA  1 
ATOM   3348 C C   . GLY A 1 450 ? -40.83200 18.72700  14.52300  1.000 48.40313  ? 450 GLY A C   1 
ATOM   3349 O O   . GLY A 1 450 ? -40.70500 19.51000  13.57900  1.000 53.34706  ? 450 GLY A O   1 
ATOM   3350 N N   . HIS A 1 451 ? -40.60400 17.41100  14.41500  1.000 52.21629  ? 451 HIS A N   1 
ATOM   3351 C CA  . HIS A 1 451 ? -40.57200 16.66600  13.14400  1.000 52.73582  ? 451 HIS A CA  1 
ATOM   3352 C C   . HIS A 1 451 ? -39.52400 17.20600  12.16800  1.000 56.05142  ? 451 HIS A C   1 
ATOM   3353 O O   . HIS A 1 451 ? -39.71400 17.19300  10.95000  1.000 61.19934  ? 451 HIS A O   1 
ATOM   3354 C CB  . HIS A 1 451 ? -41.96700 16.62300  12.50500  1.000 49.56895  ? 451 HIS A CB  1 
ATOM   3355 C CG  . HIS A 1 451 ? -43.03800 16.17000  13.44900  1.000 55.09340  ? 451 HIS A CG  1 
ATOM   3356 N ND1 . HIS A 1 451 ? -43.42800 14.85100  13.55900  1.000 64.21433  ? 451 HIS A ND1 1 
ATOM   3357 C CD2 . HIS A 1 451 ? -43.76800 16.85500  14.36300  1.000 57.50356  ? 451 HIS A CD2 1 
ATOM   3358 C CE1 . HIS A 1 451 ? -44.36600 14.74600  14.48600  1.000 64.02585  ? 451 HIS A CE1 1 
ATOM   3359 N NE2 . HIS A 1 451 ? -44.58800 15.94700  14.99200  1.000 63.96092  ? 451 HIS A NE2 1 
ATOM   3360 N N   . GLN A 1 452 ? -38.39200 17.65300  12.71000  1.000 61.25695  ? 452 GLN A N   1 
ATOM   3361 C CA  . GLN A 1 452 ? -37.26000 18.12000  11.91800  1.000 54.59441  ? 452 GLN A CA  1 
ATOM   3362 C C   . GLN A 1 452 ? -36.22500 17.03200  11.66200  1.000 60.68943  ? 452 GLN A C   1 
ATOM   3363 O O   . GLN A 1 452 ? -35.55600 17.05400  10.62000  1.000 60.93144  ? 452 GLN A O   1 
ATOM   3364 C CB  . GLN A 1 452 ? -36.58300 19.29800  12.62800  1.000 66.40047  ? 452 GLN A CB  1 
ATOM   3365 C CG  . GLN A 1 452 ? -37.37100 20.59900  12.58400  1.000 65.01141  ? 452 GLN A CG  1 
ATOM   3366 C CD  . GLN A 1 452 ? -37.10500 21.37700  11.31800  1.000 72.88679  ? 452 GLN A CD  1 
ATOM   3367 O OE1 . GLN A 1 452 ? -37.21400 20.84100  10.20900  1.000 73.07989  ? 452 GLN A OE1 1 
ATOM   3368 N NE2 . GLN A 1 452 ? -36.73000 22.64600  11.47200  1.000 75.38827  ? 452 GLN A NE2 1 
ATOM   3369 N N   . ARG A 1 453 ? -36.06900 16.09900  12.60400  1.000 58.86894  ? 453 ARG A N   1 
ATOM   3370 C CA  . ARG A 1 453 ? -35.14500 14.97600  12.50200  1.000 51.63814  ? 453 ARG A CA  1 
ATOM   3371 C C   . ARG A 1 453 ? -35.93000 13.68100  12.63100  1.000 50.66214  ? 453 ARG A C   1 
ATOM   3372 O O   . ARG A 1 453 ? -36.70500 13.51500  13.58100  1.000 48.83749  ? 453 ARG A O   1 
ATOM   3373 C CB  . ARG A 1 453 ? -34.07100 15.03300  13.59600  1.000 55.33956  ? 453 ARG A CB  1 
ATOM   3374 C CG  . ARG A 1 453 ? -33.41900 16.39700  13.76400  1.000 59.26592  ? 453 ARG A CG  1 
ATOM   3375 C CD  . ARG A 1 453 ? -32.77900 16.54600  15.14700  1.000 60.21194  ? 453 ARG A CD  1 
ATOM   3376 N NE  . ARG A 1 453 ? -31.46300 15.91800  15.22900  1.000 61.60308  ? 453 ARG A NE  1 
ATOM   3377 C CZ  . ARG A 1 453 ? -30.32100 16.56400  15.03100  1.000 56.17868  ? 453 ARG A CZ  1 
ATOM   3378 N NH1 . ARG A 1 453 ? -30.30200 17.85400  14.72900  1.000 53.06140  ? 453 ARG A NH1 1 
ATOM   3379 N NH2 . ARG A 1 453 ? -29.17000 15.90300  15.14700  1.000 56.03780  ? 453 ARG A NH2 1 
ATOM   3380 N N   . LEU A 1 454 ? -35.72100 12.77200  11.68400  1.000 51.59013  ? 454 LEU A N   1 
ATOM   3381 C CA  . LEU A 1 454 ? -36.30600 11.43900  11.69100  1.000 47.55300  ? 454 LEU A CA  1 
ATOM   3382 C C   . LEU A 1 454 ? -35.26500 10.40200  12.10300  1.000 43.73702  ? 454 LEU A C   1 
ATOM   3383 O O   . LEU A 1 454 ? -34.05100 10.62000  12.01000  1.000 47.58601  ? 454 LEU A O   1 
ATOM   3384 C CB  . LEU A 1 454 ? -36.88100 11.08300  10.31100  1.000 52.23227  ? 454 LEU A CB  1 
ATOM   3385 C CG  . LEU A 1 454 ? -38.35600 11.39200  10.00200  1.000 56.58967  ? 454 LEU A CG  1 
ATOM   3386 C CD1 . LEU A 1 454 ? -38.62600 11.36500  8.48900   1.000 53.52266  ? 454 LEU A CD1 1 
ATOM   3387 C CD2 . LEU A 1 454 ? -39.30100 10.41800  10.73500  1.000 52.61026  ? 454 LEU A CD2 1 
ATOM   3388 N N   . HIS A 1 455 ? -35.76000 9.26600   12.57400  1.000 41.89827  ? 455 HIS A N   1 
ATOM   3389 C CA  . HIS A 1 455 ? -34.93800 8.13100   12.95700  1.000 44.84516  ? 455 HIS A CA  1 
ATOM   3390 C C   . HIS A 1 455 ? -35.64200 6.85000   12.54100  1.000 43.05582  ? 455 HIS A C   1 
ATOM   3391 O O   . HIS A 1 455 ? -36.87500 6.76800   12.59500  1.000 44.40853  ? 455 HIS A O   1 
ATOM   3392 C CB  . HIS A 1 455 ? -34.66500 8.10600   14.46900  1.000 36.55836  ? 455 HIS A CB  1 
ATOM   3393 C CG  . HIS A 1 455 ? -33.93400 9.31400   14.95800  1.000 43.87490  ? 455 HIS A CG  1 
ATOM   3394 N ND1 . HIS A 1 455 ? -32.59900 9.52900   14.69400  1.000 43.42997  ? 455 HIS A ND1 1 
ATOM   3395 C CD2 . HIS A 1 455 ? -34.35600 10.38800  15.66600  1.000 44.38569  ? 455 HIS A CD2 1 
ATOM   3396 C CE1 . HIS A 1 455 ? -32.22800 10.67700  15.23100  1.000 40.56320  ? 455 HIS A CE1 1 
ATOM   3397 N NE2 . HIS A 1 455 ? -33.27300 11.21700  15.82700  1.000 43.76213  ? 455 HIS A NE2 1 
ATOM   3398 N N   . PRO A 1 456 ? -34.89100 5.84300   12.10900  1.000 40.34080  ? 456 PRO A N   1 
ATOM   3399 C CA  . PRO A 1 456 ? -35.50800 4.55200   11.78700  1.000 43.65738  ? 456 PRO A CA  1 
ATOM   3400 C C   . PRO A 1 456 ? -36.24800 3.99000   12.99600  1.000 41.67497  ? 456 PRO A C   1 
ATOM   3401 O O   . PRO A 1 456 ? -36.05300 4.42700   14.12900  1.000 42.00057  ? 456 PRO A O   1 
ATOM   3402 C CB  . PRO A 1 456 ? -34.30500 3.67400   11.40100  1.000 42.81952  ? 456 PRO A CB  1 
ATOM   3403 C CG  . PRO A 1 456 ? -33.14300 4.31000   12.14800  1.000 40.81166  ? 456 PRO A CG  1 
ATOM   3404 C CD  . PRO A 1 456 ? -33.41600 5.78500   12.08200  1.000 40.12081  ? 456 PRO A CD  1 
ATOM   3405 N N   . ARG A 1 457 ? -37.11300 3.01000   12.74600  1.000 38.81151  ? 457 ARG A N   1 
ATOM   3406 C CA  . ARG A 1 457 ? -37.84700 2.41000   13.84900  1.000 38.25484  ? 457 ARG A CA  1 
ATOM   3407 C C   . ARG A 1 457 ? -36.90800 1.59900   14.73600  1.000 39.74019  ? 457 ARG A C   1 
ATOM   3408 O O   . ARG A 1 457 ? -35.82800 1.16800   14.32300  1.000 34.91079  ? 457 ARG A O   1 
ATOM   3409 C CB  . ARG A 1 457 ? -38.98400 1.52800   13.33800  1.000 39.37369  ? 457 ARG A CB  1 
ATOM   3410 C CG  . ARG A 1 457 ? -38.55100 0.28600   12.57200  1.000 37.00634  ? 457 ARG A CG  1 
ATOM   3411 C CD  . ARG A 1 457 ? -39.73400 -0.25100  11.79300  1.000 38.24615  ? 457 ARG A CD  1 
ATOM   3412 N NE  . ARG A 1 457 ? -39.42700 -1.41800  10.97000  1.000 36.99755  ? 457 ARG A NE  1 
ATOM   3413 C CZ  . ARG A 1 457 ? -39.23400 -1.37700  9.65800   1.000 34.07215  ? 457 ARG A CZ  1 
ATOM   3414 N NH1 . ARG A 1 457 ? -39.19300 -0.22700  8.99800   1.000 29.17830  ? 457 ARG A NH1 1 
ATOM   3415 N NH2 . ARG A 1 457 ? -39.10400 -2.52100  8.98600   1.000 31.17281  ? 457 ARG A NH2 1 
ATOM   3416 N N   . GLY A 1 458 ? -37.33500 1.39800   15.98600  1.000 44.40197  ? 458 GLY A N   1 
ATOM   3417 C CA  . GLY A 1 458 ? -36.48400 0.73700   16.95500  1.000 40.68874  ? 458 GLY A CA  1 
ATOM   3418 C C   . GLY A 1 458 ? -36.47300 -0.76900  16.86500  1.000 45.35717  ? 458 GLY A C   1 
ATOM   3419 O O   . GLY A 1 458 ? -35.50900 -1.39600  17.31400  1.000 51.83087  ? 458 GLY A O   1 
ATOM   3420 N N   . SER A 1 459 ? -37.50200 -1.36300  16.27200  1.000 43.48563  ? 459 SER A N   1 
ATOM   3421 C CA  . SER A 1 459 ? -37.69900 -2.79900  16.35100  1.000 46.14353  ? 459 SER A CA  1 
ATOM   3422 C C   . SER A 1 459 ? -38.14600 -3.35800  15.01100  1.000 39.20328  ? 459 SER A C   1 
ATOM   3423 O O   . SER A 1 459 ? -38.83200 -2.69300  14.23900  1.000 45.66926  ? 459 SER A O   1 
ATOM   3424 C CB  . SER A 1 459 ? -38.74300 -3.14800  17.40400  1.000 41.47513  ? 459 SER A CB  1 
ATOM   3425 O OG  . SER A 1 459 ? -39.12500 -4.50300  17.26500  1.000 54.97503  ? 459 SER A OG  1 
ATOM   3426 N N   . PHE A 1 460 ? -37.78600 -4.61100  14.76900  1.000 44.20040  ? 460 PHE A N   1 
ATOM   3427 C CA  . PHE A 1 460 ? -38.17500 -5.33100  13.56500  1.000 45.37525  ? 460 PHE A CA  1 
ATOM   3428 C C   . PHE A 1 460 ? -38.83800 -6.65200  13.91600  1.000 47.58525  ? 460 PHE A C   1 
ATOM   3429 O O   . PHE A 1 460 ? -38.77500 -7.60300  13.13300  1.000 46.76777  ? 460 PHE A O   1 
ATOM   3430 C CB  . PHE A 1 460 ? -36.96900 -5.58700  12.65900  1.000 44.88706  ? 460 PHE A CB  1 
ATOM   3431 C CG  . PHE A 1 460 ? -36.29100 -4.34200  12.19300  1.000 41.05517  ? 460 PHE A CG  1 
ATOM   3432 C CD1 . PHE A 1 460 ? -36.72600 -3.68900  11.05200  1.000 41.82824  ? 460 PHE A CD1 1 
ATOM   3433 C CD2 . PHE A 1 460 ? -35.22000 -3.82400  12.89200  1.000 39.78572  ? 460 PHE A CD2 1 
ATOM   3434 C CE1 . PHE A 1 460 ? -36.10100 -2.53000  10.61600  1.000 40.58252  ? 460 PHE A CE1 1 
ATOM   3435 C CE2 . PHE A 1 460 ? -34.58900 -2.67300  12.46800  1.000 44.56642  ? 460 PHE A CE2 1 
ATOM   3436 C CZ  . PHE A 1 460 ? -35.02700 -2.02600  11.32500  1.000 43.16438  ? 460 PHE A CZ  1 
ATOM   3437 N N   . GLN A 1 461 ? -39.45100 -6.74000  15.09400  1.000 47.56247  ? 461 GLN A N   1 
ATOM   3438 C CA  . GLN A 1 461 ? -40.04200 -8.00100  15.51500  1.000 50.85013  ? 461 GLN A CA  1 
ATOM   3439 C C   . GLN A 1 461 ? -41.32400 -8.26100  14.73200  1.000 50.76392  ? 461 GLN A C   1 
ATOM   3440 O O   . GLN A 1 461 ? -41.98000 -7.33200  14.24900  1.000 52.05021  ? 461 GLN A O   1 
ATOM   3441 C CB  . GLN A 1 461 ? -40.31700 -8.00100  17.02400  1.000 58.06217  ? 461 GLN A CB  1 
ATOM   3442 C CG  . GLN A 1 461 ? -40.20200 -9.39800  17.71000  1.000 66.71419  ? 461 GLN A CG  1 
ATOM   3443 C CD  . GLN A 1 461 ? -38.74600 -9.89300  17.92300  1.000 70.43894  ? 461 GLN A CD  1 
ATOM   3444 O OE1 . GLN A 1 461 ? -37.86800 -9.69000  17.07400  1.000 68.23846  ? 461 GLN A OE1 1 
ATOM   3445 N NE2 . GLN A 1 461 ? -38.50300 -10.55600 19.06100  1.000 66.40676  ? 461 GLN A NE2 1 
ATOM   3446 N N   . ALA A 1 462 ? -41.65100 -9.54500  14.57500  1.000 47.07030  ? 462 ALA A N   1 
ATOM   3447 C CA  . ALA A 1 462 ? -42.78000 -9.93700  13.74400  1.000 43.53635  ? 462 ALA A CA  1 
ATOM   3448 C C   . ALA A 1 462 ? -44.05000 -9.26200  14.22600  1.000 45.26491  ? 462 ALA A C   1 
ATOM   3449 O O   . ALA A 1 462 ? -44.33400 -9.22000  15.42400  1.000 48.26697  ? 462 ALA A O   1 
ATOM   3450 C CB  . ALA A 1 462 ? -42.96200 -11.44900 13.76700  1.000 48.20012  ? 462 ALA A CB  1 
ATOM   3451 N N   . TRP A 1 463 ? -44.81000 -8.72200  13.28300  1.000 42.20809  ? 463 TRP A N   1 
ATOM   3452 C CA  . TRP A 1 463 ? -46.01200 -7.96700  13.60800  1.000 46.97608  ? 463 TRP A CA  1 
ATOM   3453 C C   . TRP A 1 463 ? -47.06500 -8.34900  12.57700  1.000 47.53024  ? 463 TRP A C   1 
ATOM   3454 O O   . TRP A 1 463 ? -46.90800 -8.06200  11.38600  1.000 47.21341  ? 463 TRP A O   1 
ATOM   3455 C CB  . TRP A 1 463 ? -45.72100 -6.47000  13.61500  1.000 43.59437  ? 463 TRP A CB  1 
ATOM   3456 C CG  . TRP A 1 463 ? -46.74400 -5.63100  14.27900  1.000 48.20146  ? 463 TRP A CG  1 
ATOM   3457 C CD1 . TRP A 1 463 ? -46.74600 -5.19400  15.57900  1.000 52.43421  ? 463 TRP A CD1 1 
ATOM   3458 C CD2 . TRP A 1 463 ? -47.90400 -5.07200  13.66700  1.000 55.22085  ? 463 TRP A CD2 1 
ATOM   3459 N NE1 . TRP A 1 463 ? -47.85400 -4.40300  15.81200  1.000 53.39640  ? 463 TRP A NE1 1 
ATOM   3460 C CE2 . TRP A 1 463 ? -48.58000 -4.31600  14.65300  1.000 60.54049  ? 463 TRP A CE2 1 
ATOM   3461 C CE3 . TRP A 1 463 ? -48.45000 -5.14800  12.38100  1.000 54.10630  ? 463 TRP A CE3 1 
ATOM   3462 C CZ2 . TRP A 1 463 ? -49.77400 -3.63800  14.38800  1.000 64.70006  ? 463 TRP A CZ2 1 
ATOM   3463 C CZ3 . TRP A 1 463 ? -49.64000 -4.47100  12.12000  1.000 59.63801  ? 463 TRP A CZ3 1 
ATOM   3464 C CH2 . TRP A 1 463 ? -50.28600 -3.72500  13.11900  1.000 59.97039  ? 463 TRP A CH2 1 
ATOM   3465 N N   . GLU A 1 464 ? -48.11800 -9.01400  13.04600  1.000 47.33519  ? 464 GLU A N   1 
ATOM   3466 C CA  . GLU A 1 464 ? -49.08200 -9.70900  12.20900  1.000 44.00202  ? 464 GLU A CA  1 
ATOM   3467 C C   . GLU A 1 464 ? -50.14700 -8.76000  11.68300  1.000 48.05227  ? 464 GLU A C   1 
ATOM   3468 O O   . GLU A 1 464 ? -50.51500 -7.78000  12.33300  1.000 48.59664  ? 464 GLU A O   1 
ATOM   3469 C CB  . GLU A 1 464 ? -49.77100 -10.79700 13.01800  1.000 53.79372  ? 464 GLU A CB  1 
ATOM   3470 C CG  . GLU A 1 464 ? -50.17200 -12.00900 12.24400  1.000 59.79315  ? 464 GLU A CG  1 
ATOM   3471 C CD  . GLU A 1 464 ? -49.11500 -13.06400 12.34200  1.000 67.45682  ? 464 GLU A CD  1 
ATOM   3472 O OE1 . GLU A 1 464 ? -47.96100 -12.68900 12.67100  1.000 64.44739  ? 464 GLU A OE1 1 
ATOM   3473 O OE2 . GLU A 1 464 ? -49.43900 -14.25100 12.11300  1.000 69.37333  ? 464 GLU A OE2 1 
ATOM   3474 N N   . GLU A 1 465 ? -50.67400 -9.08200  10.51000  1.000 49.18646  ? 465 GLU A N   1 
ATOM   3475 C CA  . GLU A 1 465 ? -51.79300 -8.32900  9.96700   1.000 46.98206  ? 465 GLU A CA  1 
ATOM   3476 C C   . GLU A 1 465 ? -52.51900 -9.24100  8.99500   1.000 48.76956  ? 465 GLU A C   1 
ATOM   3477 O O   . GLU A 1 465 ? -51.87800 -9.93500  8.20000   1.000 49.91787  ? 465 GLU A O   1 
ATOM   3478 C CB  . GLU A 1 465 ? -51.30900 -7.04400  9.28500   1.000 49.43813  ? 465 GLU A CB  1 
ATOM   3479 C CG  . GLU A 1 465 ? -52.34400 -6.32300  8.45900   1.000 45.70487  ? 465 GLU A CG  1 
ATOM   3480 C CD  . GLU A 1 465 ? -51.73000 -5.26000  7.56100   1.000 55.98555  ? 465 GLU A CD  1 
ATOM   3481 O OE1 . GLU A 1 465 ? -51.42100 -4.14900  8.05500   1.000 60.42312  ? 465 GLU A OE1 1 
ATOM   3482 O OE2 . GLU A 1 465 ? -51.54800 -5.54100  6.35300   1.000 59.12507  ? 465 GLU A OE2 1 
ATOM   3483 N N   . THR A 1 466 ? -53.83900 -9.28300  9.09400   1.000 46.24592  ? 466 THR A N   1 
ATOM   3484 C CA  . THR A 1 466 ? -54.64900 -10.09500 8.20000   1.000 47.87729  ? 466 THR A CA  1 
ATOM   3485 C C   . THR A 1 466 ? -55.39400 -9.17500  7.24700   1.000 40.62036  ? 466 THR A C   1 
ATOM   3486 O O   . THR A 1 466 ? -55.90100 -8.12000  7.64500   1.000 44.43635  ? 466 THR A O   1 
ATOM   3487 C CB  . THR A 1 466 ? -55.63200 -10.97800 8.97100   1.000 43.15954  ? 466 THR A CB  1 
ATOM   3488 O OG1 . THR A 1 466 ? -56.57800 -10.14600 9.65100   1.000 55.32761  ? 466 THR A OG1 1 
ATOM   3489 C CG2 . THR A 1 466 ? -54.88600 -11.81800 10.00700  1.000 37.44456  ? 466 THR A CG2 1 
ATOM   3490 N N   . VAL A 1 467 ? -55.42100 -9.55200  5.98600   1.000 39.87979  ? 467 VAL A N   1 
ATOM   3491 C CA  . VAL A 1 467 ? -56.00700 -8.72800  4.94200   1.000 43.00027  ? 467 VAL A CA  1 
ATOM   3492 C C   . VAL A 1 467 ? -57.30000 -9.40600  4.52200   1.000 36.67581  ? 467 VAL A C   1 
ATOM   3493 O O   . VAL A 1 467 ? -57.27800 -10.50700 3.95900   1.000 39.47126  ? 467 VAL A O   1 
ATOM   3494 C CB  . VAL A 1 467 ? -55.04300 -8.54400  3.76000   1.000 45.54160  ? 467 VAL A CB  1 
ATOM   3495 C CG1 . VAL A 1 467 ? -55.59200 -7.52700  2.77800   1.000 38.81817  ? 467 VAL A CG1 1 
ATOM   3496 C CG2 . VAL A 1 467 ? -53.65000 -8.13900  4.25500   1.000 37.18986  ? 467 VAL A CG2 1 
ATOM   3497 N N   . ARG A 1 468 ? -58.42700 -8.76200  4.81100   1.000 37.17694  ? 468 ARG A N   1 
ATOM   3498 C CA  . ARG A 1 468 ? -59.74400 -9.29200  4.49600   1.000 35.88627  ? 468 ARG A CA  1 
ATOM   3499 C C   . ARG A 1 468 ? -60.28900 -8.59700  3.25300   1.000 37.39835  ? 468 ARG A C   1 
ATOM   3500 O O   . ARG A 1 468 ? -59.64200 -7.73400  2.66800   1.000 40.12620  ? 468 ARG A O   1 
ATOM   3501 C CB  . ARG A 1 468 ? -60.69300 -9.11900  5.69000   1.000 36.55173  ? 468 ARG A CB  1 
ATOM   3502 C CG  . ARG A 1 468 ? -60.26800 -9.85700  6.96300   1.000 37.29873  ? 468 ARG A CG  1 
ATOM   3503 C CD  . ARG A 1 468 ? -60.18500 -11.35700 6.74000   1.000 30.71184  ? 468 ARG A CD  1 
ATOM   3504 N NE  . ARG A 1 468 ? -61.45900 -11.89200 6.27100   1.000 36.45416  ? 468 ARG A NE  1 
ATOM   3505 C CZ  . ARG A 1 468 ? -62.35000 -12.49800 7.05100   1.000 38.12026  ? 468 ARG A CZ  1 
ATOM   3506 N NH1 . ARG A 1 468 ? -62.13300 -12.67500 8.34400   1.000 29.06621  ? 468 ARG A NH1 1 
ATOM   3507 N NH2 . ARG A 1 468 ? -63.48500 -12.94500 6.51900   1.000 38.25108  ? 468 ARG A NH2 1 
ATOM   3508 N N   . ASP A 1 469 ? -61.49300 -8.99800  2.84100   1.000 40.01914  ? 469 ASP A N   1 
ATOM   3509 C CA  . ASP A 1 469 ? -62.27100 -8.36100  1.77000   1.000 38.60076  ? 469 ASP A CA  1 
ATOM   3510 C C   . ASP A 1 469 ? -61.48400 -8.14700  0.47200   1.000 41.67170  ? 469 ASP A C   1 
ATOM   3511 O O   . ASP A 1 469 ? -61.87600 -7.31400  -0.36400  1.000 41.87618  ? 469 ASP A O   1 
ATOM   3512 C CB  . ASP A 1 469 ? -62.86500 -7.02800  2.23000   1.000 41.70227  ? 469 ASP A CB  1 
ATOM   3513 C CG  . ASP A 1 469 ? -63.55200 -7.12900  3.56600   1.000 46.69768  ? 469 ASP A CG  1 
ATOM   3514 O OD1 . ASP A 1 469 ? -62.81800 -7.18200  4.57700   1.000 54.69626  ? 469 ASP A OD1 1 
ATOM   3515 O OD2 . ASP A 1 469 ? -64.80900 -7.15700  3.60700   1.000 39.60654  ? 469 ASP A OD2 1 
ATOM   3516 N N   . THR A 1 470 ? -60.39600 -8.88000  0.23900   1.000 36.74816  ? 470 THR A N   1 
ATOM   3517 C CA  . THR A 1 470 ? -59.72600 -8.80800  -1.05300  1.000 40.54052  ? 470 THR A CA  1 
ATOM   3518 C C   . THR A 1 470 ? -59.61100 -10.20700 -1.65100  1.000 40.01877  ? 470 THR A C   1 
ATOM   3519 O O   . THR A 1 470 ? -59.34800 -11.18600 -0.94300  1.000 36.39083  ? 470 THR A O   1 
ATOM   3520 C CB  . THR A 1 470 ? -58.32800 -8.15900  -0.95500  1.000 36.77781  ? 470 THR A CB  1 
ATOM   3521 O OG1 . THR A 1 470 ? -57.43300 -9.05700  -0.29900  1.000 48.95187  ? 470 THR A OG1 1 
ATOM   3522 C CG2 . THR A 1 470 ? -58.38300 -6.88600  -0.15200  1.000 37.59567  ? 470 THR A CG2 1 
ATOM   3523 N N   . SER A 1 471 ? -59.81600 -10.29200 -2.96000  1.000 39.53111  ? 471 SER A N   1 
ATOM   3524 C CA  . SER A 1 471 ? -59.78500 -11.56300 -3.66100  1.000 42.84193  ? 471 SER A CA  1 
ATOM   3525 C C   . SER A 1 471 ? -58.37100 -11.86400 -4.15400  1.000 38.42628  ? 471 SER A C   1 
ATOM   3526 O O   . SER A 1 471 ? -57.42900 -11.10100 -3.93100  1.000 38.89914  ? 471 SER A O   1 
ATOM   3527 C CB  . SER A 1 471 ? -60.77000 -11.53800 -4.82500  1.000 34.45224  ? 471 SER A CB  1 
ATOM   3528 O OG  . SER A 1 471 ? -60.32500 -10.62200 -5.81000  1.000 35.43618  ? 471 SER A OG  1 
ATOM   3529 N N   . LEU A 1 472 ? -58.21900 -13.00400 -4.81900  1.000 38.46146  ? 472 LEU A N   1 
ATOM   3530 C CA  . LEU A 1 472 ? -57.01600 -13.24400 -5.59700  1.000 37.10420  ? 472 LEU A CA  1 
ATOM   3531 C C   . LEU A 1 472 ? -56.99000 -12.27900 -6.77900  1.000 40.37210  ? 472 LEU A C   1 
ATOM   3532 O O   . LEU A 1 472 ? -58.03500 -12.02700 -7.40600  1.000 40.34315  ? 472 LEU A O   1 
ATOM   3533 C CB  . LEU A 1 472 ? -56.96200 -14.68300 -6.10400  1.000 37.93523  ? 472 LEU A CB  1 
ATOM   3534 C CG  . LEU A 1 472 ? -57.00600 -15.77700 -5.04400  1.000 39.31631  ? 472 LEU A CG  1 
ATOM   3535 C CD1 . LEU A 1 472 ? -56.71500 -17.12000 -5.68200  1.000 36.49683  ? 472 LEU A CD1 1 
ATOM   3536 C CD2 . LEU A 1 472 ? -56.02900 -15.47100 -3.91500  1.000 40.07113  ? 472 LEU A CD2 1 
ATOM   3537 N N   . PRO A 1 473 ? -55.83100 -11.71200 -7.09700  1.000 36.74959  ? 473 PRO A N   1 
ATOM   3538 C CA  . PRO A 1 473 ? -55.75100 -10.74200 -8.19000  1.000 39.50764  ? 473 PRO A CA  1 
ATOM   3539 C C   . PRO A 1 473 ? -56.05300 -11.37800 -9.53200  1.000 39.58598  ? 473 PRO A C   1 
ATOM   3540 O O   . PRO A 1 473 ? -55.91500 -12.58600 -9.73600  1.000 42.77139  ? 473 PRO A O   1 
ATOM   3541 C CB  . PRO A 1 473 ? -54.29700 -10.28600 -8.13300  1.000 38.57686  ? 473 PRO A CB  1 
ATOM   3542 C CG  . PRO A 1 473 ? -53.61100 -11.49500 -7.65200  1.000 29.76174  ? 473 PRO A CG  1 
ATOM   3543 C CD  . PRO A 1 473 ? -54.50100 -12.02200 -6.56200  1.000 31.48454  ? 473 PRO A CD  1 
ATOM   3544 N N   . TRP A 1 474 ? -56.46300 -10.52500 -10.46100 1.000 39.80894  ? 474 TRP A N   1 
ATOM   3545 C CA  . TRP A 1 474 ? -56.73100 -10.94600 -11.82400 1.000 37.65743  ? 474 TRP A CA  1 
ATOM   3546 C C   . TRP A 1 474 ? -55.43500 -10.93300 -12.62500 1.000 46.10473  ? 474 TRP A C   1 
ATOM   3547 O O   . TRP A 1 474 ? -54.78500 -9.88700  -12.75600 1.000 47.72943  ? 474 TRP A O   1 
ATOM   3548 C CB  . TRP A 1 474 ? -57.78900 -10.02800 -12.41900 1.000 40.33775  ? 474 TRP A CB  1 
ATOM   3549 C CG  . TRP A 1 474 ? -59.00800 -10.08100 -11.56600 1.000 43.49733  ? 474 TRP A CG  1 
ATOM   3550 C CD1 . TRP A 1 474 ? -59.37300 -9.20600  -10.56700 1.000 35.62908  ? 474 TRP A CD1 1 
ATOM   3551 C CD2 . TRP A 1 474 ? -60.00100 -11.11100 -11.58600 1.000 38.66298  ? 474 TRP A CD2 1 
ATOM   3552 N NE1 . TRP A 1 474 ? -60.55600 -9.61900  -9.99600  1.000 40.79095  ? 474 TRP A NE1 1 
ATOM   3553 C CE2 . TRP A 1 474 ? -60.96300 -10.78400 -10.60200 1.000 39.24517  ? 474 TRP A CE2 1 
ATOM   3554 C CE3 . TRP A 1 474 ? -60.18300 -12.26700 -12.35500 1.000 32.81273  ? 474 TRP A CE3 1 
ATOM   3555 C CZ2 . TRP A 1 474 ? -62.08300 -11.58200 -10.36200 1.000 34.97641  ? 474 TRP A CZ2 1 
ATOM   3556 C CZ3 . TRP A 1 474 ? -61.30300 -13.06400 -12.11300 1.000 34.73743  ? 474 TRP A CZ3 1 
ATOM   3557 C CH2 . TRP A 1 474 ? -62.23200 -12.71900 -11.12600 1.000 34.55094  ? 474 TRP A CH2 1 
ATOM   3558 N N   . LYS A 1 475 ? -55.04300 -12.09900 -13.13300 1.000 47.21054  ? 475 LYS A N   1 
ATOM   3559 C CA  . LYS A 1 475 ? -53.79500 -12.23000 -13.86800 1.000 49.55038  ? 475 LYS A CA  1 
ATOM   3560 C C   . LYS A 1 475 ? -54.02900 -11.99200 -15.36100 1.000 49.85166  ? 475 LYS A C   1 
ATOM   3561 O O   . LYS A 1 475 ? -55.16600 -11.94000 -15.84100 1.000 50.28132  ? 475 LYS A O   1 
ATOM   3562 C CB  . LYS A 1 475 ? -53.17200 -13.60900 -13.62100 1.000 50.87620  ? 475 LYS A CB  1 
ATOM   3563 C CG  . LYS A 1 475 ? -52.66800 -13.85300 -12.17800 1.000 51.75132  ? 475 LYS A CG  1 
ATOM   3564 C CD  . LYS A 1 475 ? -51.18900 -13.43400 -11.95800 1.000 63.94296  ? 475 LYS A CD  1 
ATOM   3565 C CE  . LYS A 1 475 ? -50.19800 -14.22600 -12.83600 1.000 62.73540  ? 475 LYS A CE  1 
ATOM   3566 N NZ  . LYS A 1 475 ? -48.94000 -14.61500 -12.12000 1.000 61.17729  ? 475 LYS A NZ  1 
ATOM   3567 N N   . ARG A 1 476 ? -52.92300 -11.82000 -16.09200 1.000 52.36384  ? 476 ARG A N   1 
ATOM   3568 C CA  . ARG A 1 476 ? -52.99400 -11.63000 -17.53800 1.000 53.93144  ? 476 ARG A CA  1 
ATOM   3569 C C   . ARG A 1 476 ? -53.86700 -12.69900 -18.18500 1.000 49.47454  ? 476 ARG A C   1 
ATOM   3570 O O   . ARG A 1 476 ? -54.74200 -12.39300 -19.00300 1.000 50.18697  ? 476 ARG A O   1 
ATOM   3571 C CB  . ARG A 1 476 ? -51.58600 -11.64800 -18.15300 1.000 61.54797  ? 476 ARG A CB  1 
ATOM   3572 C CG  . ARG A 1 476 ? -50.75000 -10.38800 -17.90900 1.000 79.21332  ? 476 ARG A CG  1 
ATOM   3573 C CD  . ARG A 1 476 ? -49.59600 -10.60500 -16.90200 1.000 83.46579  ? 476 ARG A CD  1 
ATOM   3574 N NE  . ARG A 1 476 ? -49.13000 -9.34400  -16.32300 1.000 92.88523  ? 476 ARG A NE  1 
ATOM   3575 C CZ  . ARG A 1 476 ? -49.41300 -8.92900  -15.09100 1.000 93.85419  ? 476 ARG A CZ  1 
ATOM   3576 N NH1 . ARG A 1 476 ? -50.10700 -9.68400  -14.24600 1.000 79.30431  ? 476 ARG A NH1 1 
ATOM   3577 N NH2 . ARG A 1 476 ? -48.99000 -7.72800  -14.69400 1.000 85.00939  ? 476 ARG A NH2 1 
ATOM   3578 N N   . ALA A 1 477 ? -53.64500 -13.96100 -17.81900 1.000 41.80761  ? 477 ALA A N   1 
ATOM   3579 C CA  . ALA A 1 477 ? -54.41500 -15.04600 -18.41200 1.000 41.30678  ? 477 ALA A CA  1 
ATOM   3580 C C   . ALA A 1 477 ? -55.90700 -14.86800 -18.14800 1.000 41.48451  ? 477 ALA A C   1 
ATOM   3581 O O   . ALA A 1 477 ? -56.72800 -14.99700 -19.06500 1.000 43.98139  ? 477 ALA A O   1 
ATOM   3582 C CB  . ALA A 1 477 ? -53.92200 -16.38800 -17.87700 1.000 36.08739  ? 477 ALA A CB  1 
ATOM   3583 N N   . ASP A 1 478 ? -56.27800 -14.57800 -16.89700 1.000 42.93849  ? 478 ASP A N   1 
ATOM   3584 C CA  . ASP A 1 478 ? -57.67800 -14.31300 -16.57900 1.000 41.33146  ? 478 ASP A CA  1 
ATOM   3585 C C   . ASP A 1 478 ? -58.24300 -13.25600 -17.51600 1.000 41.91571  ? 478 ASP A C   1 
ATOM   3586 O O   . ASP A 1 478 ? -59.27400 -13.47000 -18.17000 1.000 39.78184  ? 478 ASP A O   1 
ATOM   3587 C CB  . ASP A 1 478 ? -57.82000 -13.86900 -15.12100 1.000 34.96901  ? 478 ASP A CB  1 
ATOM   3588 C CG  . ASP A 1 478 ? -57.19300 -14.84400 -14.15100 1.000 38.71190  ? 478 ASP A CG  1 
ATOM   3589 O OD1 . ASP A 1 478 ? -57.39600 -16.07300 -14.32100 1.000 34.34688  ? 478 ASP A OD1 1 
ATOM   3590 O OD2 . ASP A 1 478 ? -56.47500 -14.38000 -13.22800 1.000 38.80459  ? 478 ASP A OD2 1 
ATOM   3591 N N   . LEU A 1 479 ? -57.55500 -12.11200 -17.61600 1.000 41.13276  ? 479 LEU A N   1 
ATOM   3592 C CA  . LEU A 1 479 ? -58.01200 -11.05800 -18.51700 1.000 43.90108  ? 479 LEU A CA  1 
ATOM   3593 C C   . LEU A 1 479 ? -58.07200 -11.56500 -19.95100 1.000 38.69681  ? 479 LEU A C   1 
ATOM   3594 O O   . LEU A 1 479 ? -59.06500 -11.34400 -20.65500 1.000 37.14004  ? 479 LEU A O   1 
ATOM   3595 C CB  . LEU A 1 479 ? -57.10600 -9.82700  -18.40100 1.000 45.06366  ? 479 LEU A CB  1 
ATOM   3596 C CG  . LEU A 1 479 ? -57.24900 -9.06600  -17.07700 1.000 46.07459  ? 479 LEU A CG  1 
ATOM   3597 C CD1 . LEU A 1 479 ? -56.60700 -7.68000  -17.12700 1.000 46.66597  ? 479 LEU A CD1 1 
ATOM   3598 C CD2 . LEU A 1 479 ? -58.72100 -8.95100  -16.71000 1.000 47.75306  ? 479 LEU A CD2 1 
ATOM   3599 N N   . GLY A 1 480 ? -57.04100 -12.29100 -20.38200 1.000 36.80191  ? 480 GLY A N   1 
ATOM   3600 C CA  . GLY A 1 480 ? -57.02500 -12.79600 -21.74000 1.000 30.72812  ? 480 GLY A CA  1 
ATOM   3601 C C   . GLY A 1 480 ? -58.19900 -13.70600 -22.02900 1.000 39.59108  ? 480 GLY A C   1 
ATOM   3602 O O   . GLY A 1 480 ? -58.85800 -13.57600 -23.06700 1.000 36.86621  ? 480 GLY A O   1 
ATOM   3603 N N   . ALA A 1 481 ? -58.48900 -14.62500 -21.10000 1.000 32.12284  ? 481 ALA A N   1 
ATOM   3604 C CA  . ALA A 1 481 ? -59.57800 -15.57400 -21.28400 1.000 37.20210  ? 481 ALA A CA  1 
ATOM   3605 C C   . ALA A 1 481 ? -60.91900 -14.86300 -21.36900 1.000 41.59654  ? 481 ALA A C   1 
ATOM   3606 O O   . ALA A 1 481 ? -61.79600 -15.25700 -22.15400 1.000 37.23520  ? 481 ALA A O   1 
ATOM   3607 C CB  . ALA A 1 481 ? -59.58600 -16.58300 -20.13800 1.000 36.85966  ? 481 ALA A CB  1 
ATOM   3608 N N   . ALA A 1 482 ? -61.09700 -13.81500 -20.56400 1.000 33.96279  ? 482 ALA A N   1 
ATOM   3609 C CA  . ALA A 1 482 ? -62.36900 -13.11300 -20.55500 1.000 37.14057  ? 482 ALA A CA  1 
ATOM   3610 C C   . ALA A 1 482 ? -62.62900 -12.48900 -21.91000 1.000 41.48156  ? 482 ALA A C   1 
ATOM   3611 O O   . ALA A 1 482 ? -63.70700 -12.65900 -22.49600 1.000 41.50832  ? 482 ALA A O   1 
ATOM   3612 C CB  . ALA A 1 482 ? -62.37600 -12.04700 -19.46300 1.000 41.03689  ? 482 ALA A CB  1 
ATOM   3613 N N   . GLU A 1 483 ? -61.63800 -11.78000 -22.43600 1.000 33.67999  ? 483 GLU A N   1 
ATOM   3614 C CA  . GLU A 1 483 ? -61.81900 -11.14100 -23.72700 1.000 39.93847  ? 483 GLU A CA  1 
ATOM   3615 C C   . GLU A 1 483 ? -62.11100 -12.18000 -24.80600 1.000 41.44184  ? 483 GLU A C   1 
ATOM   3616 O O   . GLU A 1 483 ? -63.03500 -12.00900 -25.60800 1.000 39.09314  ? 483 GLU A O   1 
ATOM   3617 C CB  . GLU A 1 483 ? -60.58000 -10.29900 -24.04000 1.000 38.74511  ? 483 GLU A CB  1 
ATOM   3618 C CG  . GLU A 1 483 ? -60.30200 -10.08300 -25.51100 1.000 50.95951  ? 483 GLU A CG  1 
ATOM   3619 C CD  . GLU A 1 483 ? -61.24300 -9.08400  -26.15200 1.000 55.40885  ? 483 GLU A CD  1 
ATOM   3620 O OE1 . GLU A 1 483 ? -60.91700 -7.87800  -26.14100 1.000 61.51888  ? 483 GLU A OE1 1 
ATOM   3621 O OE2 . GLU A 1 483 ? -62.30700 -9.50300  -26.66700 1.000 54.32310  ? 483 GLU A OE2 1 
ATOM   3622 N N   . GLY A 1 484 ? -61.36600 -13.29200 -24.80500 1.000 43.39581  ? 484 GLY A N   1 
ATOM   3623 C CA  . GLY A 1 484 ? -61.62000 -14.34300 -25.77400 1.000 36.55633  ? 484 GLY A CA  1 
ATOM   3624 C C   . GLY A 1 484 ? -63.03800 -14.86300 -25.69100 1.000 40.44945  ? 484 GLY A C   1 
ATOM   3625 O O   . GLY A 1 484 ? -63.66400 -15.15400 -26.71300 1.000 48.48149  ? 484 GLY A O   1 
ATOM   3626 N N   . PHE A 1 485 ? -63.56900 -14.96700 -24.47100 1.000 44.66708  ? 485 PHE A N   1 
ATOM   3627 C CA  . PHE A 1 485 ? -64.94200 -15.43300 -24.27000 1.000 42.86314  ? 485 PHE A CA  1 
ATOM   3628 C C   . PHE A 1 485 ? -65.95000 -14.43000 -24.82700 1.000 45.30372  ? 485 PHE A C   1 
ATOM   3629 O O   . PHE A 1 485 ? -66.97100 -14.81800 -25.41400 1.000 42.14691  ? 485 PHE A O   1 
ATOM   3630 C CB  . PHE A 1 485 ? -65.17500 -15.69300 -22.77300 1.000 46.34053  ? 485 PHE A CB  1 
ATOM   3631 C CG  . PHE A 1 485 ? -66.49700 -16.36700 -22.45100 1.000 50.43427  ? 485 PHE A CG  1 
ATOM   3632 C CD1 . PHE A 1 485 ? -66.70300 -17.70600 -22.73500 1.000 48.89998  ? 485 PHE A CD1 1 
ATOM   3633 C CD2 . PHE A 1 485 ? -67.52100 -15.66200 -21.82900 1.000 53.49242  ? 485 PHE A CD2 1 
ATOM   3634 C CE1 . PHE A 1 485 ? -67.91800 -18.33000 -22.42500 1.000 50.50922  ? 485 PHE A CE1 1 
ATOM   3635 C CE2 . PHE A 1 485 ? -68.73600 -16.28000 -21.51700 1.000 48.61309  ? 485 PHE A CE2 1 
ATOM   3636 C CZ  . PHE A 1 485 ? -68.92700 -17.61900 -21.81700 1.000 47.74560  ? 485 PHE A CZ  1 
ATOM   3637 N N   . ARG A 1 486 ? -65.67600 -13.13400 -24.65400 1.000 43.89824  ? 486 ARG A N   1 
ATOM   3638 C CA  . ARG A 1 486 ? -66.47800 -12.10700 -25.31200 1.000 46.70786  ? 486 ARG A CA  1 
ATOM   3639 C C   . ARG A 1 486 ? -66.38100 -12.22500 -26.83300 1.000 51.19069  ? 486 ARG A C   1 
ATOM   3640 O O   . ARG A 1 486 ? -67.36200 -11.98600 -27.54900 1.000 49.27614  ? 486 ARG A O   1 
ATOM   3641 C CB  . ARG A 1 486 ? -66.02900 -10.72600 -24.83500 1.000 42.76872  ? 486 ARG A CB  1 
ATOM   3642 C CG  . ARG A 1 486 ? -66.27100 -9.61400  -25.82600 1.000 48.24377  ? 486 ARG A CG  1 
ATOM   3643 C CD  . ARG A 1 486 ? -65.31500 -8.46900  -25.58000 1.000 47.85114  ? 486 ARG A CD  1 
ATOM   3644 N NE  . ARG A 1 486 ? -65.57300 -7.35800  -26.48500 1.000 51.08828  ? 486 ARG A NE  1 
ATOM   3645 C CZ  . ARG A 1 486 ? -64.79300 -7.00200  -27.49600 1.000 46.10743  ? 486 ARG A CZ  1 
ATOM   3646 N NH1 . ARG A 1 486 ? -63.65300 -7.62200  -27.74300 1.000 43.21715  ? 486 ARG A NH1 1 
ATOM   3647 N NH2 . ARG A 1 486 ? -65.16800 -5.99600  -28.27800 1.000 52.34979  ? 486 ARG A NH2 1 
ATOM   3648 N N   . GLY A 1 487 ? -65.20300 -12.59400 -27.34200 1.000 49.15969  ? 487 GLY A N   1 
ATOM   3649 C CA  . GLY A 1 487 ? -65.09800 -12.91000 -28.74900 1.000 43.49789  ? 487 GLY A CA  1 
ATOM   3650 C C   . GLY A 1 487 ? -66.11300 -13.95300 -29.16300 1.000 49.26553  ? 487 GLY A C   1 
ATOM   3651 O O   . GLY A 1 487 ? -66.82400 -13.78100 -30.15700 1.000 54.53245  ? 487 GLY A O   1 
ATOM   3652 N N   . ALA A 1 488 ? -66.23300 -15.02500 -28.37500 1.000 46.58404  ? 488 ALA A N   1 
ATOM   3653 C CA  . ALA A 1 488 ? -67.16300 -16.10000 -28.71300 1.000 47.87010  ? 488 ALA A CA  1 
ATOM   3654 C C   . ALA A 1 488 ? -68.61100 -15.62100 -28.67000 1.000 48.40815  ? 488 ALA A C   1 
ATOM   3655 O O   . ALA A 1 488 ? -69.38100 -15.85300 -29.60900 1.000 58.15474  ? 488 ALA A O   1 
ATOM   3656 C CB  . ALA A 1 488 ? -66.96100 -17.28500 -27.76800 1.000 47.83365  ? 488 ALA A CB  1 
ATOM   3657 N N   . LEU A 1 489 ? -68.99500 -14.87200 -27.64000 1.000 49.61336  ? 489 LEU A N   1 
ATOM   3658 C CA  . LEU A 1 489 ? -70.42400 -14.47000 -27.47800 1.000 58.35408  ? 489 LEU A CA  1 
ATOM   3659 C C   . LEU A 1 489 ? -70.80200 -13.25200 -28.34100 1.000 60.47364  ? 489 LEU A C   1 
ATOM   3660 O O   . LEU A 1 489 ? -70.81700 -12.14200 -27.80600 1.000 62.08924  ? 489 LEU A O   1 
ATOM   3661 C CB  . LEU A 1 489 ? -70.67300 -14.18800 -25.99300 1.000 52.67945  ? 489 LEU A CB  1 
ATOM   3662 C CG  . LEU A 1 489 ? -70.53000 -15.37300 -25.04000 1.000 50.88475  ? 489 LEU A CG  1 
ATOM   3663 C CD1 . LEU A 1 489 ? -71.23500 -15.08300 -23.72800 1.000 46.12226  ? 489 LEU A CD1 1 
ATOM   3664 C CD2 . LEU A 1 489 ? -71.07300 -16.64900 -25.66000 1.000 48.74324  ? 489 LEU A CD2 1 
ATOM   3665 N N   . VAL A 1 490 ? -71.15800 -13.47900 -29.61200 1.000 64.90907  ? 490 VAL A N   1 
ATOM   3666 C CA  . VAL A 1 490 ? -71.27400 -12.42100 -30.66800 1.000 66.73730  ? 490 VAL A CA  1 
ATOM   3667 C C   . VAL A 1 490 ? -70.69900 -11.10700 -30.13300 1.000 67.12920  ? 490 VAL A C   1 
ATOM   3668 O O   . VAL A 1 490 ? -69.50300 -10.88000 -30.36700 1.000 71.22323  ? 490 VAL A O   1 
ATOM   3669 C CB  . VAL A 1 490 ? -72.72100 -12.22700 -31.16200 1.000 63.57423  ? 490 VAL A CB  1 
ATOM   3670 C CG1 . VAL A 1 490 ? -73.74800 -12.73400 -30.16200 1.000 66.13492  ? 490 VAL A CG1 1 
ATOM   3671 C CG2 . VAL A 1 490 ? -73.00100 -10.77800 -31.52400 1.000 62.70631  ? 490 VAL A CG2 1 
ATOM   3672 N N   . ASP B 1 9   ? -32.70600 -43.80500 -44.70100 1.000 85.36236  ? 9   ASP B N   1 
ATOM   3673 C CA  . ASP B 1 9   ? -31.82700 -44.92000 -45.04600 1.000 87.62860  ? 9   ASP B CA  1 
ATOM   3674 C C   . ASP B 1 9   ? -30.67500 -45.04500 -44.02700 1.000 83.82143  ? 9   ASP B C   1 
ATOM   3675 O O   . ASP B 1 9   ? -29.57400 -44.51600 -44.23800 1.000 75.18512  ? 9   ASP B O   1 
ATOM   3676 C CB  . ASP B 1 9   ? -31.28700 -44.75000 -46.47900 1.000 86.57079  ? 9   ASP B CB  1 
ATOM   3677 C CG  . ASP B 1 9   ? -30.92800 -46.08100 -47.14900 1.000 87.49596  ? 9   ASP B CG  1 
ATOM   3678 O OD1 . ASP B 1 9   ? -31.82700 -46.94200 -47.32500 1.000 83.97235  ? 9   ASP B OD1 1 
ATOM   3679 O OD2 . ASP B 1 9   ? -29.74500 -46.25300 -47.51400 1.000 77.83655  ? 9   ASP B OD2 1 
ATOM   3680 N N   . LEU B 1 10  ? -30.96000 -45.73500 -42.91300 1.000 84.66530  ? 10  LEU B N   1 
ATOM   3681 C CA  . LEU B 1 10  ? -29.94200 -46.13800 -41.94500 1.000 83.99117  ? 10  LEU B CA  1 
ATOM   3682 C C   . LEU B 1 10  ? -28.78500 -46.82100 -42.68100 1.000 79.38951  ? 10  LEU B C   1 
ATOM   3683 O O   . LEU B 1 10  ? -28.77900 -48.04300 -42.87400 1.000 79.38837  ? 10  LEU B O   1 
ATOM   3684 C CB  . LEU B 1 10  ? -30.54400 -47.06100 -40.86600 1.000 82.75393  ? 10  LEU B CB  1 
ATOM   3685 C CG  . LEU B 1 10  ? -31.44900 -46.51200 -39.74300 1.000 83.67147  ? 10  LEU B CG  1 
ATOM   3686 C CD1 . LEU B 1 10  ? -30.81500 -45.32100 -38.99400 1.000 69.52756  ? 10  LEU B CD1 1 
ATOM   3687 C CD2 . LEU B 1 10  ? -32.85100 -46.15600 -40.24500 1.000 79.10852  ? 10  LEU B CD2 1 
ATOM   3688 N N   . SER B 1 11  ? -27.80900 -46.02400 -43.10100 1.000 69.99636  ? 11  SER B N   1 
ATOM   3689 C CA  . SER B 1 11  ? -26.77300 -46.43400 -44.02800 1.000 69.80831  ? 11  SER B CA  1 
ATOM   3690 C C   . SER B 1 11  ? -25.43300 -46.54200 -43.32300 1.000 65.08149  ? 11  SER B C   1 
ATOM   3691 O O   . SER B 1 11  ? -25.33300 -46.45500 -42.09300 1.000 59.80616  ? 11  SER B O   1 
ATOM   3692 C CB  . SER B 1 11  ? -26.67400 -45.43900 -45.18800 1.000 72.82607  ? 11  SER B CB  1 
ATOM   3693 O OG  . SER B 1 11  ? -26.09100 -44.20900 -44.76100 1.000 64.89366  ? 11  SER B OG  1 
ATOM   3694 N N   . GLN B 1 12  ? -24.39100 -46.70200 -44.13900 1.000 65.64738  ? 12  GLN B N   1 
ATOM   3695 C CA  . GLN B 1 12  ? -23.03000 -46.81500 -43.63700 1.000 61.60324  ? 12  GLN B CA  1 
ATOM   3696 C C   . GLN B 1 12  ? -22.68600 -45.68300 -42.67400 1.000 54.79226  ? 12  GLN B C   1 
ATOM   3697 O O   . GLN B 1 12  ? -22.00200 -45.90000 -41.66700 1.000 56.18920  ? 12  GLN B O   1 
ATOM   3698 C CB  . GLN B 1 12  ? -22.06200 -46.84000 -44.82400 1.000 62.19263  ? 12  GLN B CB  1 
ATOM   3699 C CG  . GLN B 1 12  ? -21.74900 -48.23000 -45.38300 1.000 67.38648  ? 12  GLN B CG  1 
ATOM   3700 C CD  . GLN B 1 12  ? -20.48400 -48.83900 -44.77100 1.000 72.35732  ? 12  GLN B CD  1 
ATOM   3701 O OE1 . GLN B 1 12  ? -19.61800 -48.12500 -44.26400 1.000 67.24319  ? 12  GLN B OE1 1 
ATOM   3702 N NE2 . GLN B 1 12  ? -20.37500 -50.16400 -44.82300 1.000 77.31357  ? 12  GLN B NE2 1 
ATOM   3703 N N   . CYS B 1 13  ? -23.16200 -44.46900 -42.95300 1.000 51.28956  ? 13  CYS B N   1 
ATOM   3704 C CA  . CYS B 1 13  ? -22.79100 -43.33500 -42.11200 1.000 50.70048  ? 13  CYS B CA  1 
ATOM   3705 C C   . CYS B 1 13  ? -23.34900 -43.47300 -40.70000 1.000 49.83063  ? 13  CYS B C   1 
ATOM   3706 O O   . CYS B 1 13  ? -22.65000 -43.19500 -39.72000 1.000 47.04998  ? 13  CYS B O   1 
ATOM   3707 C CB  . CYS B 1 13  ? -23.26500 -42.03500 -42.74500 1.000 47.77694  ? 13  CYS B CB  1 
ATOM   3708 S SG  . CYS B 1 13  ? -22.30400 -41.62200 -44.17400 1.000 45.82956  ? 13  CYS B SG  1 
ATOM   3709 N N   . ASP B 1 14  ? -24.60400 -43.89900 -40.57400 1.000 48.18345  ? 14  ASP B N   1 
ATOM   3710 C CA  . ASP B 1 14  ? -25.23000 -44.01800 -39.26300 1.000 51.22110  ? 14  ASP B CA  1 
ATOM   3711 C C   . ASP B 1 14  ? -24.75500 -45.23000 -38.46200 1.000 48.84768  ? 14  ASP B C   1 
ATOM   3712 O O   . ASP B 1 14  ? -25.00900 -45.28500 -37.25800 1.000 45.17428  ? 14  ASP B O   1 
ATOM   3713 C CB  . ASP B 1 14  ? -26.76200 -44.08700 -39.39700 1.000 50.80179  ? 14  ASP B CB  1 
ATOM   3714 C CG  . ASP B 1 14  ? -27.38500 -42.77900 -39.90300 1.000 52.47997  ? 14  ASP B CG  1 
ATOM   3715 O OD1 . ASP B 1 14  ? -26.76900 -41.69100 -39.77100 1.000 45.83359  ? 14  ASP B OD1 1 
ATOM   3716 O OD2 . ASP B 1 14  ? -28.52100 -42.84400 -40.42100 1.000 54.68815  ? 14  ASP B OD2 1 
ATOM   3717 N N   . ARG B 1 15  ? -24.07300 -46.19300 -39.07600 1.000 53.19742  ? 15  ARG B N   1 
ATOM   3718 C CA  . ARG B 1 15  ? -23.80500 -47.45700 -38.39800 1.000 50.91861  ? 15  ARG B CA  1 
ATOM   3719 C C   . ARG B 1 15  ? -22.46200 -47.51500 -37.67700 1.000 45.91493  ? 15  ARG B C   1 
ATOM   3720 O O   . ARG B 1 15  ? -22.23600 -48.45700 -36.91300 1.000 41.66705  ? 15  ARG B O   1 
ATOM   3721 C CB  . ARG B 1 15  ? -23.87800 -48.62000 -39.39900 1.000 55.80304  ? 15  ARG B CB  1 
ATOM   3722 C CG  . ARG B 1 15  ? -25.22400 -49.32500 -39.41200 1.000 61.24898  ? 15  ARG B CG  1 
ATOM   3723 C CD  . ARG B 1 15  ? -25.31900 -50.32500 -40.55200 1.000 71.36319  ? 15  ARG B CD  1 
ATOM   3724 N NE  . ARG B 1 15  ? -26.66900 -50.39100 -41.10800 1.000 79.21283  ? 15  ARG B NE  1 
ATOM   3725 C CZ  . ARG B 1 15  ? -26.93900 -50.54200 -42.40000 1.000 76.56177  ? 15  ARG B CZ  1 
ATOM   3726 N NH1 . ARG B 1 15  ? -25.97200 -50.61800 -43.30300 1.000 74.17180  ? 15  ARG B NH1 1 
ATOM   3727 N NH2 . ARG B 1 15  ? -28.20800 -50.59800 -42.80000 1.000 70.36165  ? 15  ARG B NH2 1 
ATOM   3728 N N   . GLU B 1 16  ? -21.56000 -46.56900 -37.89900 1.000 48.00300  ? 16  GLU B N   1 
ATOM   3729 C CA  . GLU B 1 16  ? -20.21100 -46.68700 -37.32600 1.000 38.44682  ? 16  GLU B CA  1 
ATOM   3730 C C   . GLU B 1 16  ? -20.26300 -46.52500 -35.81100 1.000 35.77839  ? 16  GLU B C   1 
ATOM   3731 O O   . GLU B 1 16  ? -20.78800 -45.51500 -35.32900 1.000 38.34823  ? 16  GLU B O   1 
ATOM   3732 C CB  . GLU B 1 16  ? -19.29000 -45.63500 -37.93200 1.000 39.71700  ? 16  GLU B CB  1 
ATOM   3733 C CG  . GLU B 1 16  ? -17.85600 -45.66900 -37.40800 1.000 38.14459  ? 16  GLU B CG  1 
ATOM   3734 C CD  . GLU B 1 16  ? -16.97800 -44.60100 -38.03800 1.000 41.04665  ? 16  GLU B CD  1 
ATOM   3735 O OE1 . GLU B 1 16  ? -17.49500 -43.50200 -38.34700 1.000 36.29083  ? 16  GLU B OE1 1 
ATOM   3736 O OE2 . GLU B 1 16  ? -15.76400 -44.85800 -38.21700 1.000 43.67787  ? 16  GLU B OE2 1 
ATOM   3737 N N   . PRO B 1 17  ? -19.75300 -47.48300 -35.01600 1.000 39.14788  ? 17  PRO B N   1 
ATOM   3738 C CA  . PRO B 1 17  ? -19.78100 -47.30000 -33.55600 1.000 33.71592  ? 17  PRO B CA  1 
ATOM   3739 C C   . PRO B 1 17  ? -18.65900 -46.37700 -33.09700 1.000 40.02957  ? 17  PRO B C   1 
ATOM   3740 O O   . PRO B 1 17  ? -17.56500 -46.82000 -32.69800 1.000 34.97263  ? 17  PRO B O   1 
ATOM   3741 C CB  . PRO B 1 17  ? -19.62900 -48.73000 -33.02200 1.000 31.58091  ? 17  PRO B CB  1 
ATOM   3742 C CG  . PRO B 1 17  ? -18.86000 -49.43200 -34.07000 1.000 30.76518  ? 17  PRO B CG  1 
ATOM   3743 C CD  . PRO B 1 17  ? -19.22300 -48.80700 -35.39800 1.000 28.41010  ? 17  PRO B CD  1 
ATOM   3744 N N   . ILE B 1 18  ? -18.94800 -45.07200 -33.16700 1.000 38.45429  ? 18  ILE B N   1 
ATOM   3745 C CA  . ILE B 1 18  ? -17.94600 -44.04200 -32.92700 1.000 33.27258  ? 18  ILE B CA  1 
ATOM   3746 C C   . ILE B 1 18  ? -17.50100 -43.96400 -31.47900 1.000 29.84213  ? 18  ILE B C   1 
ATOM   3747 O O   . ILE B 1 18  ? -16.58200 -43.21300 -31.17200 1.000 30.79006  ? 18  ILE B O   1 
ATOM   3748 C CB  . ILE B 1 18  ? -18.46800 -42.66000 -33.35600 1.000 26.46144  ? 18  ILE B CB  1 
ATOM   3749 C CG1 . ILE B 1 18  ? -19.57400 -42.19900 -32.40800 1.000 31.98332  ? 18  ILE B CG1 1 
ATOM   3750 C CG2 . ILE B 1 18  ? -18.97800 -42.71900 -34.77900 1.000 33.50784  ? 18  ILE B CG2 1 
ATOM   3751 C CD1 . ILE B 1 18  ? -20.00400 -40.74100 -32.59800 1.000 31.29276  ? 18  ILE B CD1 1 
ATOM   3752 N N   . HIS B 1 19  ? -18.14000 -44.69200 -30.57800 1.000 32.52360  ? 19  HIS B N   1 
ATOM   3753 C CA  . HIS B 1 19  ? -17.67700 -44.75400 -29.19800 1.000 34.62544  ? 19  HIS B CA  1 
ATOM   3754 C C   . HIS B 1 19  ? -16.78300 -45.95400 -28.91500 1.000 34.59947  ? 19  HIS B C   1 
ATOM   3755 O O   . HIS B 1 19  ? -16.07600 -45.95700 -27.89600 1.000 34.70264  ? 19  HIS B O   1 
ATOM   3756 C CB  . HIS B 1 19  ? -18.87200 -44.78500 -28.24200 1.000 32.80942  ? 19  HIS B CB  1 
ATOM   3757 C CG  . HIS B 1 19  ? -19.84000 -45.89300 -28.51800 1.000 35.58894  ? 19  HIS B CG  1 
ATOM   3758 N ND1 . HIS B 1 19  ? -20.40700 -46.09500 -29.75700 1.000 39.00714  ? 19  HIS B ND1 1 
ATOM   3759 C CD2 . HIS B 1 19  ? -20.35800 -46.84600 -27.70600 1.000 38.34930  ? 19  HIS B CD2 1 
ATOM   3760 C CE1 . HIS B 1 19  ? -21.22300 -47.13400 -29.70200 1.000 40.09836  ? 19  HIS B CE1 1 
ATOM   3761 N NE2 . HIS B 1 19  ? -21.21600 -47.60400 -28.46700 1.000 39.99789  ? 19  HIS B NE2 1 
ATOM   3762 N N   . LEU B 1 20  ? -16.79800 -46.96000 -29.78900 1.000 33.08990  ? 20  LEU B N   1 
ATOM   3763 C CA  . LEU B 1 20  ? -16.02700 -48.18800 -29.62600 1.000 34.75377  ? 20  LEU B CA  1 
ATOM   3764 C C   . LEU B 1 20  ? -14.92500 -48.29100 -30.67200 1.000 30.87468  ? 20  LEU B C   1 
ATOM   3765 O O   . LEU B 1 20  ? -14.66300 -49.36600 -31.21200 1.000 32.76852  ? 20  LEU B O   1 
ATOM   3766 C CB  . LEU B 1 20  ? -16.93400 -49.41100 -29.71100 1.000 36.05724  ? 20  LEU B CB  1 
ATOM   3767 C CG  . LEU B 1 20  ? -18.14600 -49.38600 -28.79300 1.000 34.60035  ? 20  LEU B CG  1 
ATOM   3768 C CD1 . LEU B 1 20  ? -19.05600 -50.53400 -29.16400 1.000 25.02590  ? 20  LEU B CD1 1 
ATOM   3769 C CD2 . LEU B 1 20  ? -17.68600 -49.48100 -27.33600 1.000 31.03496  ? 20  LEU B CD2 1 
ATOM   3770 N N   . LEU B 1 21  ? -14.28500 -47.17400 -30.99400 1.000 25.90291  ? 21  LEU B N   1 
ATOM   3771 C CA  . LEU B 1 21  ? -13.19500 -47.21200 -31.95900 1.000 33.76173  ? 21  LEU B CA  1 
ATOM   3772 C C   . LEU B 1 21  ? -11.84400 -47.50000 -31.31800 1.000 32.31589  ? 21  LEU B C   1 
ATOM   3773 O O   . LEU B 1 21  ? -10.85400 -47.63300 -32.04700 1.000 34.25094  ? 21  LEU B O   1 
ATOM   3774 C CB  . LEU B 1 21  ? -13.12900 -45.88900 -32.73600 1.000 36.27885  ? 21  LEU B CB  1 
ATOM   3775 C CG  . LEU B 1 21  ? -14.40600 -45.54000 -33.52400 1.000 34.31111  ? 21  LEU B CG  1 
ATOM   3776 C CD1 . LEU B 1 21  ? -14.32300 -44.14500 -34.13800 1.000 34.87915  ? 21  LEU B CD1 1 
ATOM   3777 C CD2 . LEU B 1 21  ? -14.68700 -46.58900 -34.59600 1.000 36.21725  ? 21  LEU B CD2 1 
ATOM   3778 N N   . GLY B 1 22  ? -11.77900 -47.54800 -29.98800 1.000 29.58839  ? 22  GLY B N   1 
ATOM   3779 C CA  . GLY B 1 22  ? -10.57900 -48.01400 -29.28400 1.000 29.51514  ? 22  GLY B CA  1 
ATOM   3780 C C   . GLY B 1 22  ? -9.29000  -47.25000 -29.53200 1.000 31.70977  ? 22  GLY B C   1 
ATOM   3781 O O   . GLY B 1 22  ? -8.20400  -47.84900 -29.49100 1.000 29.53948  ? 22  GLY B O   1 
ATOM   3782 N N   . GLY B 1 23  ? -9.36100  -45.93000 -29.72500 1.000 28.50979  ? 23  GLY B N   1 
ATOM   3783 C CA  . GLY B 1 23  ? -8.15100  -45.12700 -29.76600 1.000 25.58793  ? 23  GLY B CA  1 
ATOM   3784 C C   . GLY B 1 23  ? -8.36600  -43.76700 -29.13500 1.000 27.05530  ? 23  GLY B C   1 
ATOM   3785 O O   . GLY B 1 23  ? -9.49400  -43.29200 -29.01700 1.000 28.42909  ? 23  GLY B O   1 
ATOM   3786 N N   . ILE B 1 24  ? -7.25800  -43.12500 -28.74200 1.000 29.66526  ? 24  ILE B N   1 
ATOM   3787 C CA  . ILE B 1 24  ? -7.32700  -41.77900 -28.17800 1.000 27.60958  ? 24  ILE B CA  1 
ATOM   3788 C C   . ILE B 1 24  ? -6.35400  -40.84200 -28.89100 1.000 30.71113  ? 24  ILE B C   1 
ATOM   3789 O O   . ILE B 1 24  ? -5.47200  -41.25900 -29.64800 1.000 33.94183  ? 24  ILE B O   1 
ATOM   3790 C CB  . ILE B 1 24  ? -7.04500  -41.75400 -26.66900 1.000 31.15396  ? 24  ILE B CB  1 
ATOM   3791 C CG1 . ILE B 1 24  ? -5.59900  -42.21600 -26.39900 1.000 29.50162  ? 24  ILE B CG1 1 
ATOM   3792 C CG2 . ILE B 1 24  ? -8.09800  -42.57600 -25.91600 1.000 21.90624  ? 24  ILE B CG2 1 
ATOM   3793 C CD1 . ILE B 1 24  ? -5.03600  -41.65900 -25.12600 1.000 24.27775  ? 24  ILE B CD1 1 
ATOM   3794 N N   . GLN B 1 25  ? -6.52300  -39.55400 -28.61200 1.000 29.84045  ? 25  GLN B N   1 
ATOM   3795 C CA  . GLN B 1 25  ? -5.70000  -38.51400 -29.20600 1.000 30.32115  ? 25  GLN B CA  1 
ATOM   3796 C C   . GLN B 1 25  ? -4.36000  -38.42100 -28.49300 1.000 33.53309  ? 25  GLN B C   1 
ATOM   3797 O O   . GLN B 1 25  ? -4.25900  -38.63600 -27.28000 1.000 34.15477  ? 25  GLN B O   1 
ATOM   3798 C CB  . GLN B 1 25  ? -6.43900  -37.17500 -29.15600 1.000 31.46100  ? 25  GLN B CB  1 
ATOM   3799 C CG  . GLN B 1 25  ? -7.45400  -37.02100 -30.29500 1.000 30.06124  ? 25  GLN B CG  1 
ATOM   3800 C CD  . GLN B 1 25  ? -8.34000  -35.79100 -30.15300 1.000 40.20823  ? 25  GLN B CD  1 
ATOM   3801 O OE1 . GLN B 1 25  ? -7.89600  -34.64600 -30.36200 1.000 34.66310  ? 25  GLN B OE1 1 
ATOM   3802 N NE2 . GLN B 1 25  ? -9.61300  -36.02200 -29.80400 1.000 32.07333  ? 25  GLN B NE2 1 
ATOM   3803 N N   . SER B 1 26  ? -3.32400  -38.07800 -29.25900 1.000 33.78816  ? 26  SER B N   1 
ATOM   3804 C CA  . SER B 1 26  ? -1.95300  -38.26700 -28.78700 1.000 36.08230  ? 26  SER B CA  1 
ATOM   3805 C C   . SER B 1 26  ? -1.54400  -37.27600 -27.69800 1.000 37.14157  ? 26  SER B C   1 
ATOM   3806 O O   . SER B 1 26  ? -0.58400  -37.53900 -26.96200 1.000 43.59901  ? 26  SER B O   1 
ATOM   3807 C CB  . SER B 1 26  ? -0.97200  -38.18800 -29.97000 1.000 37.06061  ? 26  SER B CB  1 
ATOM   3808 O OG  . SER B 1 26  ? -1.32900  -37.15900 -30.87900 1.000 43.46782  ? 26  SER B OG  1 
ATOM   3809 N N   . HIS B 1 27  ? -2.23400  -36.15400 -27.55900 1.000 31.67130  ? 27  HIS B N   1 
ATOM   3810 C CA  . HIS B 1 27  ? -1.77300  -35.22500 -26.54100 1.000 35.28068  ? 27  HIS B CA  1 
ATOM   3811 C C   . HIS B 1 27  ? -2.08300  -35.67800 -25.12600 1.000 34.68547  ? 27  HIS B C   1 
ATOM   3812 O O   . HIS B 1 27  ? -1.68100  -34.98000 -24.18800 1.000 37.71340  ? 27  HIS B O   1 
ATOM   3813 C CB  . HIS B 1 27  ? -2.39900  -33.86200 -26.76700 1.000 34.79995  ? 27  HIS B CB  1 
ATOM   3814 C CG  . HIS B 1 27  ? -3.88000  -33.90900 -26.87800 1.000 29.76306  ? 27  HIS B CG  1 
ATOM   3815 N ND1 . HIS B 1 27  ? -4.52700  -34.16500 -28.06900 1.000 30.57371  ? 27  HIS B ND1 1 
ATOM   3816 C CD2 . HIS B 1 27  ? -4.84700  -33.74100 -25.94800 1.000 35.38273  ? 27  HIS B CD2 1 
ATOM   3817 C CE1 . HIS B 1 27  ? -5.83400  -34.13600 -27.86800 1.000 33.21252  ? 27  HIS B CE1 1 
ATOM   3818 N NE2 . HIS B 1 27  ? -6.05500  -33.87500 -26.59100 1.000 34.69142  ? 27  HIS B NE2 1 
ATOM   3819 N N   . GLY B 1 28  ? -2.79300  -36.79100 -24.93400 1.000 33.53530  ? 28  GLY B N   1 
ATOM   3820 C CA  . GLY B 1 28  ? -3.18900  -37.23300 -23.61300 1.000 28.39792  ? 28  GLY B CA  1 
ATOM   3821 C C   . GLY B 1 28  ? -2.87500  -38.70500 -23.38500 1.000 31.39306  ? 28  GLY B C   1 
ATOM   3822 O O   . GLY B 1 28  ? -2.41800  -39.42100 -24.28400 1.000 37.01845  ? 28  GLY B O   1 
ATOM   3823 N N   . VAL B 1 29  ? -3.13500  -39.13400 -22.15900 1.000 28.83073  ? 29  VAL B N   1 
ATOM   3824 C CA  . VAL B 1 29  ? -2.91500  -40.50800 -21.72400 1.000 32.89371  ? 29  VAL B CA  1 
ATOM   3825 C C   . VAL B 1 29  ? -4.18200  -40.95400 -21.01100 1.000 28.27120  ? 29  VAL B C   1 
ATOM   3826 O O   . VAL B 1 29  ? -4.82000  -40.16300 -20.31100 1.000 30.23999  ? 29  VAL B O   1 
ATOM   3827 C CB  . VAL B 1 29  ? -1.67100  -40.61400 -20.79600 1.000 35.58056  ? 29  VAL B CB  1 
ATOM   3828 C CG1 . VAL B 1 29  ? -1.49100  -42.01500 -20.21400 1.000 27.50241  ? 29  VAL B CG1 1 
ATOM   3829 C CG2 . VAL B 1 29  ? -0.40800  -40.18500 -21.53300 1.000 31.58400  ? 29  VAL B CG2 1 
ATOM   3830 N N   . LEU B 1 30  ? -4.55500  -42.20900 -21.18700 1.000 28.04922  ? 30  LEU B N   1 
ATOM   3831 C CA  . LEU B 1 30  ? -5.72700  -42.73600 -20.51400 1.000 25.78877  ? 30  LEU B CA  1 
ATOM   3832 C C   . LEU B 1 30  ? -5.34100  -43.98900 -19.73900 1.000 29.24150  ? 30  LEU B C   1 
ATOM   3833 O O   . LEU B 1 30  ? -4.63300  -44.85600 -20.25400 1.000 31.21737  ? 30  LEU B O   1 
ATOM   3834 C CB  . LEU B 1 30  ? -6.84100  -43.04300 -21.52800 1.000 26.90861  ? 30  LEU B CB  1 
ATOM   3835 C CG  . LEU B 1 30  ? -8.14700  -43.65100 -21.00100 1.000 25.46127  ? 30  LEU B CG  1 
ATOM   3836 C CD1 . LEU B 1 30  ? -9.31800  -43.35600 -21.94100 1.000 24.46003  ? 30  LEU B CD1 1 
ATOM   3837 C CD2 . LEU B 1 30  ? -7.98800  -45.15600 -20.86500 1.000 22.55655  ? 30  LEU B CD2 1 
ATOM   3838 N N   . LEU B 1 31  ? -5.83800  -44.09300 -18.51100 1.000 24.76394  ? 31  LEU B N   1 
ATOM   3839 C CA  . LEU B 1 31  ? -5.72700  -45.30700 -17.72300 1.000 29.88669  ? 31  LEU B CA  1 
ATOM   3840 C C   . LEU B 1 31  ? -7.11100  -45.71800 -17.25300 1.000 32.87699  ? 31  LEU B C   1 
ATOM   3841 O O   . LEU B 1 31  ? -7.98800  -44.87100 -17.05400 1.000 33.71429  ? 31  LEU B O   1 
ATOM   3842 C CB  . LEU B 1 31  ? -4.80000  -45.11400 -16.52500 1.000 27.36504  ? 31  LEU B CB  1 
ATOM   3843 C CG  . LEU B 1 31  ? -3.36000  -44.98400 -17.02000 1.000 24.81094  ? 31  LEU B CG  1 
ATOM   3844 C CD1 . LEU B 1 31  ? -2.91200  -43.53700 -16.93400 1.000 27.41629  ? 31  LEU B CD1 1 
ATOM   3845 C CD2 . LEU B 1 31  ? -2.41500  -45.89700 -16.27100 1.000 30.05416  ? 31  LEU B CD2 1 
ATOM   3846 N N   . ALA B 1 32  ? -7.31200  -47.02700 -17.09400 1.000 30.94459  ? 32  ALA B N   1 
ATOM   3847 C CA  . ALA B 1 32  ? -8.56500  -47.54000 -16.55400 1.000 31.16535  ? 32  ALA B CA  1 
ATOM   3848 C C   . ALA B 1 32  ? -8.27000  -48.64800 -15.55800 1.000 38.16383  ? 32  ALA B C   1 
ATOM   3849 O O   . ALA B 1 32  ? -7.46800  -49.54800 -15.84000 1.000 37.17856  ? 32  ALA B O   1 
ATOM   3850 C CB  . ALA B 1 32  ? -9.49400  -48.04700 -17.66700 1.000 32.37067  ? 32  ALA B CB  1 
ATOM   3851 N N   . PHE B 1 33  ? -8.91600  -48.56600 -14.39200 1.000 41.30461  ? 33  PHE B N   1 
ATOM   3852 C CA  . PHE B 1 33  ? -8.67800  -49.47200 -13.27900 1.000 39.52109  ? 33  PHE B CA  1 
ATOM   3853 C C   . PHE B 1 33  ? -9.94500  -50.24100 -12.94600 1.000 35.79449  ? 33  PHE B C   1 
ATOM   3854 O O   . PHE B 1 33  ? -11.05900 -49.73200 -13.10900 1.000 31.64423  ? 33  PHE B O   1 
ATOM   3855 C CB  . PHE B 1 33  ? -8.21200  -48.70900 -12.04300 1.000 36.48124  ? 33  PHE B CB  1 
ATOM   3856 C CG  . PHE B 1 33  ? -7.08900  -47.78500 -12.32200 1.000 43.55765  ? 33  PHE B CG  1 
ATOM   3857 C CD1 . PHE B 1 33  ? -5.77000  -48.24500 -12.27800 1.000 43.44527  ? 33  PHE B CD1 1 
ATOM   3858 C CD2 . PHE B 1 33  ? -7.33700  -46.45800 -12.66200 1.000 41.36824  ? 33  PHE B CD2 1 
ATOM   3859 C CE1 . PHE B 1 33  ? -4.70500  -47.39800 -12.55400 1.000 39.20905  ? 33  PHE B CE1 1 
ATOM   3860 C CE2 . PHE B 1 33  ? -6.28200  -45.60000 -12.94500 1.000 40.19546  ? 33  PHE B CE2 1 
ATOM   3861 C CZ  . PHE B 1 33  ? -4.96000  -46.07400 -12.88900 1.000 38.86629  ? 33  PHE B CZ  1 
ATOM   3862 N N   . ARG B 1 34  ? -9.75200  -51.46200 -12.44300 1.000 40.15501  ? 34  ARG B N   1 
ATOM   3863 C CA  . ARG B 1 34  ? -10.83800 -52.35200 -12.04200 1.000 41.48624  ? 34  ARG B CA  1 
ATOM   3864 C C   . ARG B 1 34  ? -10.70600 -52.74700 -10.57500 1.000 40.18749  ? 34  ARG B C   1 
ATOM   3865 O O   . ARG B 1 34  ? -9.61200  -53.06400 -10.10400 1.000 40.33386  ? 34  ARG B O   1 
ATOM   3866 C CB  . ARG B 1 34  ? -10.84700 -53.60900 -12.90500 1.000 39.27356  ? 34  ARG B CB  1 
ATOM   3867 C CG  . ARG B 1 34  ? -11.93000 -54.61800 -12.57000 1.000 44.59714  ? 34  ARG B CG  1 
ATOM   3868 C CD  . ARG B 1 34  ? -11.86500 -55.80600 -13.53200 1.000 51.87240  ? 34  ARG B CD  1 
ATOM   3869 N NE  . ARG B 1 34  ? -10.56100 -56.47400 -13.51800 1.000 55.37002  ? 34  ARG B NE  1 
ATOM   3870 C CZ  . ARG B 1 34  ? -10.22200 -57.44600 -12.67500 1.000 55.77924  ? 34  ARG B CZ  1 
ATOM   3871 N NH1 . ARG B 1 34  ? -11.05300 -57.86800 -11.73200 1.000 50.16870  ? 34  ARG B NH1 1 
ATOM   3872 N NH2 . ARG B 1 34  ? -9.02200  -58.00900 -12.77900 1.000 53.92116  ? 34  ARG B NH2 1 
ATOM   3873 N N   . GLY B 1 35  ? -11.82200 -52.70600 -9.85000  1.000 41.03460  ? 35  GLY B N   1 
ATOM   3874 C CA  . GLY B 1 35  ? -11.94000 -53.39800 -8.58400  1.000 43.35471  ? 35  GLY B CA  1 
ATOM   3875 C C   . GLY B 1 35  ? -11.27700 -52.73500 -7.38300  1.000 46.63543  ? 35  GLY B C   1 
ATOM   3876 O O   . GLY B 1 35  ? -10.70700 -51.63900 -7.47600  1.000 41.83675  ? 35  GLY B O   1 
ATOM   3877 N N   . PRO B 1 36  ? -11.32900 -53.42200 -6.22800  1.000 43.21681  ? 36  PRO B N   1 
ATOM   3878 C CA  . PRO B 1 36  ? -10.88800 -52.80300 -4.96700  1.000 38.83418  ? 36  PRO B CA  1 
ATOM   3879 C C   . PRO B 1 36  ? -9.42200  -52.42300 -4.95700  1.000 42.85470  ? 36  PRO B C   1 
ATOM   3880 O O   . PRO B 1 36  ? -9.03900  -51.47900 -4.25300  1.000 43.68229  ? 36  PRO B O   1 
ATOM   3881 C CB  . PRO B 1 36  ? -11.17100 -53.89200 -3.92200  1.000 36.52772  ? 36  PRO B CB  1 
ATOM   3882 C CG  . PRO B 1 36  ? -11.91600 -54.97900 -4.63700  1.000 41.28386  ? 36  PRO B CG  1 
ATOM   3883 C CD  . PRO B 1 36  ? -11.59800 -54.86100 -6.06700  1.000 41.45444  ? 36  PRO B CD  1 
ATOM   3884 N N   . ASP B 1 37  ? -8.58500  -53.15400 -5.69500  1.000 45.02533  ? 37  ASP B N   1 
ATOM   3885 C CA  . ASP B 1 37  ? -7.16400  -52.85500 -5.76800  1.000 42.48285  ? 37  ASP B CA  1 
ATOM   3886 C C   . ASP B 1 37  ? -6.84700  -51.76300 -6.77200  1.000 44.62295  ? 37  ASP B C   1 
ATOM   3887 O O   . ASP B 1 37  ? -5.69600  -51.30100 -6.82700  1.000 42.99072  ? 37  ASP B O   1 
ATOM   3888 C CB  . ASP B 1 37  ? -6.38300  -54.10500 -6.14800  1.000 44.66715  ? 37  ASP B CB  1 
ATOM   3889 C CG  . ASP B 1 37  ? -6.25700  -55.06400 -5.01200  1.000 54.37543  ? 37  ASP B CG  1 
ATOM   3890 O OD1 . ASP B 1 37  ? -6.22000  -54.58800 -3.86000  1.000 55.06182  ? 37  ASP B OD1 1 
ATOM   3891 O OD2 . ASP B 1 37  ? -6.20800  -56.28900 -5.27000  1.000 62.41230  ? 37  ASP B OD2 1 
ATOM   3892 N N   . ARG B 1 38  ? -7.82200  -51.36700 -7.58100  1.000 44.25635  ? 38  ARG B N   1 
ATOM   3893 C CA  . ARG B 1 38  ? -7.58500  -50.45100 -8.68800  1.000 44.62747  ? 38  ARG B CA  1 
ATOM   3894 C C   . ARG B 1 38  ? -6.42300  -50.95500 -9.55000  1.000 38.41734  ? 38  ARG B C   1 
ATOM   3895 O O   . ARG B 1 38  ? -5.36600  -50.33200 -9.67600  1.000 37.33390  ? 38  ARG B O   1 
ATOM   3896 C CB  . ARG B 1 38  ? -7.35700  -49.04100 -8.14500  1.000 44.05927  ? 38  ARG B CB  1 
ATOM   3897 C CG  . ARG B 1 38  ? -8.47100  -48.63200 -7.18300  1.000 41.63944  ? 38  ARG B CG  1 
ATOM   3898 C CD  . ARG B 1 38  ? -8.25800  -47.23200 -6.64600  1.000 59.02172  ? 38  ARG B CD  1 
ATOM   3899 N NE  . ARG B 1 38  ? -7.30200  -47.18200 -5.54200  1.000 64.08967  ? 38  ARG B NE  1 
ATOM   3900 C CZ  . ARG B 1 38  ? -7.51900  -46.55300 -4.39200  1.000 67.23774  ? 38  ARG B CZ  1 
ATOM   3901 N NH1 . ARG B 1 38  ? -8.64400  -45.88300 -4.16900  1.000 57.75316  ? 38  ARG B NH1 1 
ATOM   3902 N NH2 . ARG B 1 38  ? -6.58200  -46.59300 -3.44600  1.000 68.35928  ? 38  ARG B NH2 1 
ATOM   3903 N N   . LEU B 1 39  ? -6.62700  -52.14900 -10.09200 1.000 32.03811  ? 39  LEU B N   1 
ATOM   3904 C CA  . LEU B 1 39  ? -5.65800  -52.75900 -10.98400 1.000 34.37992  ? 39  LEU B CA  1 
ATOM   3905 C C   . LEU B 1 39  ? -5.81900  -52.19200 -12.38900 1.000 36.24725  ? 39  LEU B C   1 
ATOM   3906 O O   . LEU B 1 39  ? -6.93900  -52.01100 -12.88400 1.000 38.11026  ? 39  LEU B O   1 
ATOM   3907 C CB  . LEU B 1 39  ? -5.83800  -54.27900 -11.01200 1.000 37.95067  ? 39  LEU B CB  1 
ATOM   3908 C CG  . LEU B 1 39  ? -5.76300  -55.13100 -9.73000  1.000 37.70920  ? 39  LEU B CG  1 
ATOM   3909 C CD1 . LEU B 1 39  ? -6.19900  -56.56800 -10.00100 1.000 27.44345  ? 39  LEU B CD1 1 
ATOM   3910 C CD2 . LEU B 1 39  ? -4.36100  -55.12100 -9.13900  1.000 36.33726  ? 39  LEU B CD2 1 
ATOM   3911 N N   . LEU B 1 40  ? -4.69200  -51.90400 -13.02500 1.000 38.92616  ? 40  LEU B N   1 
ATOM   3912 C CA  . LEU B 1 40  ? -4.71100  -51.36700 -14.37100 1.000 31.20791  ? 40  LEU B CA  1 
ATOM   3913 C C   . LEU B 1 40  ? -5.25600  -52.42100 -15.31900 1.000 38.61687  ? 40  LEU B C   1 
ATOM   3914 O O   . LEU B 1 40  ? -4.67100  -53.49900 -15.46800 1.000 38.45598  ? 40  LEU B O   1 
ATOM   3915 C CB  . LEU B 1 40  ? -3.30500  -50.95200 -14.76700 1.000 36.05678  ? 40  LEU B CB  1 
ATOM   3916 C CG  . LEU B 1 40  ? -3.11300  -50.29600 -16.12400 1.000 35.69215  ? 40  LEU B CG  1 
ATOM   3917 C CD1 . LEU B 1 40  ? -3.93200  -49.04200 -16.14800 1.000 37.97039  ? 40  LEU B CD1 1 
ATOM   3918 C CD2 . LEU B 1 40  ? -1.65500  -49.96700 -16.31200 1.000 38.21244  ? 40  LEU B CD2 1 
ATOM   3919 N N   . GLU B 1 41  ? -6.39500  -52.11500 -15.93600 1.000 38.91783  ? 41  GLU B N   1 
ATOM   3920 C CA  . GLU B 1 41  ? -7.11100  -53.00300 -16.84200 1.000 33.56259  ? 41  GLU B CA  1 
ATOM   3921 C C   . GLU B 1 41  ? -6.87000  -52.64900 -18.30800 1.000 34.39217  ? 41  GLU B C   1 
ATOM   3922 O O   . GLU B 1 41  ? -6.69500  -53.54200 -19.14500 1.000 36.93824  ? 41  GLU B O   1 
ATOM   3923 C CB  . GLU B 1 41  ? -8.60700  -52.93300 -16.51000 1.000 33.94320  ? 41  GLU B CB  1 
ATOM   3924 C CG  . GLU B 1 41  ? -9.49300  -53.90200 -17.24300 1.000 42.27494  ? 41  GLU B CG  1 
ATOM   3925 C CD  . GLU B 1 41  ? -9.42500  -55.29400 -16.66800 1.000 43.69965  ? 41  GLU B CD  1 
ATOM   3926 O OE1 . GLU B 1 41  ? -9.04000  -55.43400 -15.49900 1.000 40.61244  ? 41  GLU B OE1 1 
ATOM   3927 O OE2 . GLU B 1 41  ? -9.76300  -56.25500 -17.39200 1.000 53.20860  ? 41  GLU B OE2 1 
ATOM   3928 N N   . VAL B 1 42  ? -6.85100  -51.35100 -18.62500 1.000 33.43961  ? 42  VAL B N   1 
ATOM   3929 C CA  . VAL B 1 42  ? -6.66100  -50.81700 -19.97100 1.000 32.41280  ? 42  VAL B CA  1 
ATOM   3930 C C   . VAL B 1 42  ? -5.71400  -49.62900 -19.85200 1.000 31.33416  ? 42  VAL B C   1 
ATOM   3931 O O   . VAL B 1 42  ? -5.72100  -48.91100 -18.84500 1.000 28.55113  ? 42  VAL B O   1 
ATOM   3932 C CB  . VAL B 1 42  ? -7.99600  -50.35900 -20.63200 1.000 28.64786  ? 42  VAL B CB  1 
ATOM   3933 C CG1 . VAL B 1 42  ? -7.86800  -50.29800 -22.13800 1.000 26.64893  ? 42  VAL B CG1 1 
ATOM   3934 C CG2 . VAL B 1 42  ? -9.17000  -51.26500 -20.24200 1.000 27.42370  ? 42  VAL B CG2 1 
ATOM   3935 N N   . VAL B 1 43  ? -4.90200  -49.41400 -20.88600 1.000 26.37812  ? 43  VAL B N   1 
ATOM   3936 C CA  . VAL B 1 43  ? -3.96300  -48.29300 -20.88800 1.000 31.38539  ? 43  VAL B CA  1 
ATOM   3937 C C   . VAL B 1 43  ? -3.62100  -47.93200 -22.33100 1.000 29.24249  ? 43  VAL B C   1 
ATOM   3938 O O   . VAL B 1 43  ? -3.44600  -48.81100 -23.18300 1.000 31.37246  ? 43  VAL B O   1 
ATOM   3939 C CB  . VAL B 1 43  ? -2.68800  -48.62800 -20.07300 1.000 30.59756  ? 43  VAL B CB  1 
ATOM   3940 C CG1 . VAL B 1 43  ? -1.92900  -49.76200 -20.71300 1.000 33.14176  ? 43  VAL B CG1 1 
ATOM   3941 C CG2 . VAL B 1 43  ? -1.80600  -47.41600 -19.99100 1.000 33.83045  ? 43  VAL B CG2 1 
ATOM   3942 N N   . SER B 1 44  ? -3.51300  -46.63300 -22.60000 1.000 24.75624  ? 44  SER B N   1 
ATOM   3943 C CA  . SER B 1 44  ? -3.18600  -46.19700 -23.94800 1.000 31.66869  ? 44  SER B CA  1 
ATOM   3944 C C   . SER B 1 44  ? -1.73500  -46.52700 -24.25800 1.000 30.03667  ? 44  SER B C   1 
ATOM   3945 O O   . SER B 1 44  ? -0.87500  -46.50300 -23.38200 1.000 35.35810  ? 44  SER B O   1 
ATOM   3946 C CB  . SER B 1 44  ? -3.44500  -44.69900 -24.12600 1.000 27.84670  ? 44  SER B CB  1 
ATOM   3947 O OG  . SER B 1 44  ? -2.81600  -43.94200 -23.10400 1.000 36.16624  ? 44  SER B OG  1 
ATOM   3948 N N   . ALA B 1 45  ? -1.46600  -46.82700 -25.53100 1.000 35.51131  ? 45  ALA B N   1 
ATOM   3949 C CA  . ALA B 1 45  ? -0.17700  -47.39900 -25.91200 1.000 35.54866  ? 45  ALA B CA  1 
ATOM   3950 C C   . ALA B 1 45  ? 0.98200   -46.42800 -25.71500 1.000 36.28869  ? 45  ALA B C   1 
ATOM   3951 O O   . ALA B 1 45  ? 2.13800   -46.85500 -25.69500 1.000 39.72453  ? 45  ALA B O   1 
ATOM   3952 C CB  . ALA B 1 45  ? -0.24200  -47.86900 -27.36800 1.000 29.23119  ? 45  ALA B CB  1 
ATOM   3953 N N   . ASN B 1 46  ? 0.69200   -45.14100 -25.55300 1.000 36.33765  ? 46  ASN B N   1 
ATOM   3954 C CA  . ASN B 1 46  ? 1.67300   -44.07100 -25.42000 1.000 30.24911  ? 46  ASN B CA  1 
ATOM   3955 C C   . ASN B 1 46  ? 1.96100   -43.69400 -23.97000 1.000 30.85296  ? 46  ASN B C   1 
ATOM   3956 O O   . ASN B 1 46  ? 2.52000   -42.62100 -23.72200 1.000 34.30498  ? 46  ASN B O   1 
ATOM   3957 C CB  . ASN B 1 46  ? 1.14500   -42.83300 -26.13000 1.000 33.29239  ? 46  ASN B CB  1 
ATOM   3958 C CG  . ASN B 1 46  ? -0.04400  -42.23200 -25.39200 1.000 31.13202  ? 46  ASN B CG  1 
ATOM   3959 O OD1 . ASN B 1 46  ? -0.75700  -42.93600 -24.64400 1.000 24.14227  ? 46  ASN B OD1 1 
ATOM   3960 N ND2 . ASN B 1 46  ? -0.24000  -40.92700 -25.55200 1.000 33.05708  ? 46  ASN B ND2 1 
ATOM   3961 N N   . ALA B 1 47  ? 1.54300   -44.51200 -23.00400 1.000 33.82369  ? 47  ALA B N   1 
ATOM   3962 C CA  . ALA B 1 47  ? 1.63800   -44.09400 -21.60900 1.000 35.15712  ? 47  ALA B CA  1 
ATOM   3963 C C   . ALA B 1 47  ? 3.06100   -44.08200 -21.08300 1.000 40.73699  ? 47  ALA B C   1 
ATOM   3964 O O   . ALA B 1 47  ? 3.29100   -43.54300 -19.99800 1.000 43.86517  ? 47  ALA B O   1 
ATOM   3965 C CB  . ALA B 1 47  ? 0.79300   -44.99600 -20.71900 1.000 36.14007  ? 47  ALA B CB  1 
ATOM   3966 N N   . GLN B 1 48  ? 4.02400   -44.65700 -21.80300 1.000 42.81290  ? 48  GLN B N   1 
ATOM   3967 C CA  . GLN B 1 48  ? 5.38900   -44.60500 -21.29400 1.000 47.95001  ? 48  GLN B CA  1 
ATOM   3968 C C   . GLN B 1 48  ? 5.85800   -43.16600 -21.16600 1.000 48.94118  ? 48  GLN B C   1 
ATOM   3969 O O   . GLN B 1 48  ? 6.52000   -42.81200 -20.18300 1.000 53.70431  ? 48  GLN B O   1 
ATOM   3970 C CB  . GLN B 1 48  ? 6.34000   -45.40200 -22.18200 1.000 50.19964  ? 48  GLN B CB  1 
ATOM   3971 C CG  . GLN B 1 48  ? 7.74200   -45.55200 -21.57600 1.000 53.77330  ? 48  GLN B CG  1 
ATOM   3972 C CD  . GLN B 1 48  ? 8.65200   -46.42000 -22.43000 1.000 63.92616  ? 48  GLN B CD  1 
ATOM   3973 O OE1 . GLN B 1 48  ? 8.19400   -47.36500 -23.09100 1.000 63.35166  ? 48  GLN B OE1 1 
ATOM   3974 N NE2 . GLN B 1 48  ? 9.94300   -46.09600 -22.43700 1.000 61.83046  ? 48  GLN B NE2 1 
ATOM   3975 N N   . ALA B 1 49  ? 5.47900   -42.31000 -22.12300 1.000 44.78727  ? 49  ALA B N   1 
ATOM   3976 C CA  . ALA B 1 49  ? 5.91500   -40.91500 -22.11400 1.000 48.05812  ? 49  ALA B CA  1 
ATOM   3977 C C   . ALA B 1 49  ? 5.57000   -40.18600 -20.82100 1.000 49.65322  ? 49  ALA B C   1 
ATOM   3978 O O   . ALA B 1 49  ? 6.16800   -39.14200 -20.54700 1.000 53.44067  ? 49  ALA B O   1 
ATOM   3979 C CB  . ALA B 1 49  ? 5.30800   -40.15100 -23.29200 1.000 45.43784  ? 49  ALA B CB  1 
ATOM   3980 N N   . LEU B 1 50  ? 4.63000   -40.70100 -20.01600 1.000 52.44460  ? 50  LEU B N   1 
ATOM   3981 C CA  . LEU B 1 50  ? 4.33500   -40.12500 -18.70500 1.000 46.05476  ? 50  LEU B CA  1 
ATOM   3982 C C   . LEU B 1 50  ? 4.65200   -41.03500 -17.52800 1.000 48.46234  ? 50  LEU B C   1 
ATOM   3983 O O   . LEU B 1 50  ? 5.03800   -40.53000 -16.47800 1.000 49.58756  ? 50  LEU B O   1 
ATOM   3984 C CB  . LEU B 1 50  ? 2.85300   -39.73000 -18.59100 1.000 52.62207  ? 50  LEU B CB  1 
ATOM   3985 C CG  . LEU B 1 50  ? 2.37800   -38.40100 -19.18100 1.000 59.16193  ? 50  LEU B CG  1 
ATOM   3986 C CD1 . LEU B 1 50  ? 0.97600   -38.08600 -18.67300 1.000 43.32410  ? 50  LEU B CD1 1 
ATOM   3987 C CD2 . LEU B 1 50  ? 3.35800   -37.26700 -18.87000 1.000 53.75869  ? 50  LEU B CD2 1 
ATOM   3988 N N   . LEU B 1 51  ? 4.47700   -42.34900 -17.65400 1.000 50.90237  ? 51  LEU B N   1 
ATOM   3989 C CA  . LEU B 1 51  ? 4.59200   -43.22300 -16.49300 1.000 51.87295  ? 51  LEU B CA  1 
ATOM   3990 C C   . LEU B 1 51  ? 5.98700   -43.80600 -16.31500 1.000 53.67874  ? 51  LEU B C   1 
ATOM   3991 O O   . LEU B 1 51  ? 6.25200   -44.43500 -15.28200 1.000 43.73493  ? 51  LEU B O   1 
ATOM   3992 C CB  . LEU B 1 51  ? 3.56200   -44.35400 -16.57900 1.000 46.14104  ? 51  LEU B CB  1 
ATOM   3993 C CG  . LEU B 1 51  ? 2.12700   -43.82900 -16.55300 1.000 46.90124  ? 51  LEU B CG  1 
ATOM   3994 C CD1 . LEU B 1 51  ? 1.15700   -44.94800 -16.26200 1.000 47.83094  ? 51  LEU B CD1 1 
ATOM   3995 C CD2 . LEU B 1 51  ? 1.96600   -42.68400 -15.53600 1.000 45.81649  ? 51  LEU B CD2 1 
ATOM   3996 N N   . GLY B 1 52  ? 6.87700   -43.61100 -17.28600 1.000 53.39755  ? 52  GLY B N   1 
ATOM   3997 C CA  . GLY B 1 52  ? 8.25100   -44.04600 -17.15800 1.000 54.94779  ? 52  GLY B CA  1 
ATOM   3998 C C   . GLY B 1 52  ? 8.50300   -45.51600 -17.40700 1.000 59.49444  ? 52  GLY B C   1 
ATOM   3999 O O   . GLY B 1 52  ? 9.66100   -45.94800 -17.33000 1.000 67.56404  ? 52  GLY B O   1 
ATOM   4000 N N   . ARG B 1 53  ? 7.47800   -46.30000 -17.70300 1.000 59.26844  ? 53  ARG B N   1 
ATOM   4001 C CA  . ARG B 1 53  ? 7.63500   -47.71400 -17.99400 1.000 58.81364  ? 53  ARG B CA  1 
ATOM   4002 C C   . ARG B 1 53  ? 6.84600   -48.07900 -19.24000 1.000 57.49669  ? 53  ARG B C   1 
ATOM   4003 O O   . ARG B 1 53  ? 5.88600   -47.38600 -19.60000 1.000 56.51612  ? 53  ARG B O   1 
ATOM   4004 C CB  . ARG B 1 53  ? 7.16300   -48.57000 -16.81100 1.000 59.74049  ? 53  ARG B CB  1 
ATOM   4005 C CG  . ARG B 1 53  ? 8.00300   -48.41600 -15.57400 1.000 62.70652  ? 53  ARG B CG  1 
ATOM   4006 C CD  . ARG B 1 53  ? 7.92300   -49.67800 -14.75200 1.000 77.34132  ? 53  ARG B CD  1 
ATOM   4007 N NE  . ARG B 1 53  ? 6.89300   -49.60800 -13.72400 1.000 81.40145  ? 53  ARG B NE  1 
ATOM   4008 C CZ  . ARG B 1 53  ? 7.14900   -49.48900 -12.42800 1.000 88.73146  ? 53  ARG B CZ  1 
ATOM   4009 N NH1 . ARG B 1 53  ? 8.39300   -49.42400 -11.97300 1.000 86.58811  ? 53  ARG B NH1 1 
ATOM   4010 N NH2 . ARG B 1 53  ? 6.13500   -49.44300 -11.56700 1.000 85.48638  ? 53  ARG B NH2 1 
ATOM   4011 N N   . PRO B 1 54  ? 7.22000   -49.16200 -19.91900 1.000 55.10266  ? 54  PRO B N   1 
ATOM   4012 C CA  . PRO B 1 54  ? 6.41100   -49.64500 -21.04700 1.000 51.28016  ? 54  PRO B CA  1 
ATOM   4013 C C   . PRO B 1 54  ? 5.00800   -49.99000 -20.58500 1.000 51.74261  ? 54  PRO B C   1 
ATOM   4014 O O   . PRO B 1 54  ? 4.83000   -50.64000 -19.54200 1.000 52.78970  ? 54  PRO B O   1 
ATOM   4015 C CB  . PRO B 1 54  ? 7.16700   -50.89600 -21.51900 1.000 58.23861  ? 54  PRO B CB  1 
ATOM   4016 C CG  . PRO B 1 54  ? 8.57200   -50.69600 -21.03300 1.000 62.37626  ? 54  PRO B CG  1 
ATOM   4017 C CD  . PRO B 1 54  ? 8.42900   -49.97900 -19.71900 1.000 59.92449  ? 54  PRO B CD  1 
ATOM   4018 N N   . PRO B 1 55  ? 3.98300   -49.55300 -21.31900 1.000 47.70441  ? 55  PRO B N   1 
ATOM   4019 C CA  . PRO B 1 55  ? 2.60300   -49.83400 -20.88400 1.000 49.80508  ? 55  PRO B CA  1 
ATOM   4020 C C   . PRO B 1 55  ? 2.31000   -51.31600 -20.68500 1.000 47.48683  ? 55  PRO B C   1 
ATOM   4021 O O   . PRO B 1 55  ? 1.55700   -51.67500 -19.76800 1.000 42.50100  ? 55  PRO B O   1 
ATOM   4022 C CB  . PRO B 1 55  ? 1.74900   -49.21600 -22.00900 1.000 46.91186  ? 55  PRO B CB  1 
ATOM   4023 C CG  . PRO B 1 55  ? 2.69900   -48.89200 -23.13400 1.000 44.48478  ? 55  PRO B CG  1 
ATOM   4024 C CD  . PRO B 1 55  ? 4.02500   -48.65600 -22.48600 1.000 49.80646  ? 55  PRO B CD  1 
ATOM   4025 N N   . GLU B 1 56  ? 2.89900   -52.18500 -21.51300 1.000 55.22815  ? 56  GLU B N   1 
ATOM   4026 C CA  . GLU B 1 56  ? 2.70500   -53.62900 -21.38700 1.000 54.10304  ? 56  GLU B CA  1 
ATOM   4027 C C   . GLU B 1 56  ? 3.00800   -54.11600 -19.97500 1.000 46.94468  ? 56  GLU B C   1 
ATOM   4028 O O   . GLU B 1 56  ? 2.28800   -54.96300 -19.43100 1.000 55.01479  ? 56  GLU B O   1 
ATOM   4029 C CB  . GLU B 1 56  ? 3.59200   -54.35200 -22.41000 1.000 54.14905  ? 56  GLU B CB  1 
ATOM   4030 C CG  . GLU B 1 56  ? 3.20400   -54.11900 -23.88700 1.000 60.74206  ? 56  GLU B CG  1 
ATOM   4031 C CD  . GLU B 1 56  ? 3.64100   -52.76800 -24.46900 1.000 57.54995  ? 56  GLU B CD  1 
ATOM   4032 O OE1 . GLU B 1 56  ? 3.78500   -51.78000 -23.72100 1.000 52.12624  ? 56  GLU B OE1 1 
ATOM   4033 O OE2 . GLU B 1 56  ? 3.84100   -52.70000 -25.70400 1.000 68.53179  ? 56  GLU B OE2 1 
ATOM   4034 N N   . THR B 1 57  ? 4.06000   -53.57500 -19.35900 1.000 44.73960  ? 57  THR B N   1 
ATOM   4035 C CA  . THR B 1 57  ? 4.47000   -54.02700 -18.03500 1.000 45.25540  ? 57  THR B CA  1 
ATOM   4036 C C   . THR B 1 57  ? 3.49900   -53.56900 -16.95700 1.000 45.74682  ? 57  THR B C   1 
ATOM   4037 O O   . THR B 1 57  ? 3.23800   -54.30600 -16.00500 1.000 52.74889  ? 57  THR B O   1 
ATOM   4038 C CB  . THR B 1 57  ? 5.88200   -53.52900 -17.72400 1.000 46.59701  ? 57  THR B CB  1 
ATOM   4039 O OG1 . THR B 1 57  ? 5.93100   -52.10200 -17.84200 1.000 50.99368  ? 57  THR B OG1 1 
ATOM   4040 C CG2 . THR B 1 57  ? 6.87600   -54.13400 -18.68700 1.000 50.84183  ? 57  THR B CG2 1 
ATOM   4041 N N   . LEU B 1 58  ? 2.93900   -52.36400 -17.09300 1.000 51.47170  ? 58  LEU B N   1 
ATOM   4042 C CA  . LEU B 1 58  ? 2.03100   -51.83600 -16.07800 1.000 46.35284  ? 58  LEU B CA  1 
ATOM   4043 C C   . LEU B 1 58  ? 0.69000   -52.55900 -16.01700 1.000 46.49640  ? 58  LEU B C   1 
ATOM   4044 O O   . LEU B 1 58  ? -0.01000  -52.43100 -15.00200 1.000 42.94657  ? 58  LEU B O   1 
ATOM   4045 C CB  . LEU B 1 58  ? 1.77300   -50.34900 -16.31900 1.000 47.47881  ? 58  LEU B CB  1 
ATOM   4046 C CG  . LEU B 1 58  ? 3.00200   -49.45400 -16.21600 1.000 52.13661  ? 58  LEU B CG  1 
ATOM   4047 C CD1 . LEU B 1 58  ? 2.60800   -48.02100 -16.47400 1.000 49.89607  ? 58  LEU B CD1 1 
ATOM   4048 C CD2 . LEU B 1 58  ? 3.67000   -49.59600 -14.84700 1.000 54.22300  ? 58  LEU B CD2 1 
ATOM   4049 N N   . LEU B 1 59  ? 0.30200   -53.29600 -17.06500 1.000 42.01540  ? 59  LEU B N   1 
ATOM   4050 C CA  . LEU B 1 59  ? -1.01300  -53.93000 -17.05700 1.000 44.21901  ? 59  LEU B CA  1 
ATOM   4051 C C   . LEU B 1 59  ? -1.12100  -54.94000 -15.91800 1.000 48.81732  ? 59  LEU B C   1 
ATOM   4052 O O   . LEU B 1 59  ? -0.23300  -55.78100 -15.71900 1.000 46.83665  ? 59  LEU B O   1 
ATOM   4053 C CB  . LEU B 1 59  ? -1.30600  -54.59700 -18.40100 1.000 43.45096  ? 59  LEU B CB  1 
ATOM   4054 C CG  . LEU B 1 59  ? -1.98300  -53.68500 -19.43300 1.000 39.10004  ? 59  LEU B CG  1 
ATOM   4055 C CD1 . LEU B 1 59  ? -2.24700  -54.44900 -20.70100 1.000 35.84289  ? 59  LEU B CD1 1 
ATOM   4056 C CD2 . LEU B 1 59  ? -3.27200  -53.10500 -18.89300 1.000 35.40406  ? 59  LEU B CD2 1 
ATOM   4057 N N   . GLY B 1 60  ? -2.22000  -54.84600 -15.16300 1.000 41.13047  ? 60  GLY B N   1 
ATOM   4058 C CA  . GLY B 1 60  ? -2.45200  -55.71000 -14.02600 1.000 37.45562  ? 60  GLY B CA  1 
ATOM   4059 C C   . GLY B 1 60  ? -1.92100  -55.22600 -12.68500 1.000 40.94246  ? 60  GLY B C   1 
ATOM   4060 O O   . GLY B 1 60  ? -2.15200  -55.90400 -11.67200 1.000 42.65768  ? 60  GLY B O   1 
ATOM   4061 N N   . GLN B 1 61  ? -1.21600  -54.07600 -12.63200 1.000 36.88070  ? 61  GLN B N   1 
ATOM   4062 C CA  . GLN B 1 61  ? -0.60300  -53.65500 -11.38000 1.000 40.24997  ? 61  GLN B CA  1 
ATOM   4063 C C   . GLN B 1 61  ? -1.55900  -52.80300 -10.55200 1.000 42.48555  ? 61  GLN B C   1 
ATOM   4064 O O   . GLN B 1 61  ? -2.49100  -52.18800 -11.08700 1.000 43.17899  ? 61  GLN B O   1 
ATOM   4065 C CB  . GLN B 1 61  ? 0.67900   -52.87100 -11.65900 1.000 45.01906  ? 61  GLN B CB  1 
ATOM   4066 C CG  . GLN B 1 61  ? 1.73000   -53.63000 -12.45600 1.000 47.37411  ? 61  GLN B CG  1 
ATOM   4067 C CD  . GLN B 1 61  ? 2.23100   -54.88000 -11.75200 1.000 48.31950  ? 61  GLN B CD  1 
ATOM   4068 O OE1 . GLN B 1 61  ? 2.31100   -54.93100 -10.52500 1.000 50.65136  ? 61  GLN B OE1 1 
ATOM   4069 N NE2 . GLN B 1 61  ? 2.56400   -55.90500 -12.53500 1.000 58.19071  ? 61  GLN B NE2 1 
ATOM   4070 N N   . PRO B 1 62  ? -1.38300  -52.77700 -9.22600  1.000 48.36905  ? 62  PRO B N   1 
ATOM   4071 C CA  . PRO B 1 62  ? -2.17900  -51.86100 -8.40700  1.000 42.21170  ? 62  PRO B CA  1 
ATOM   4072 C C   . PRO B 1 62  ? -1.82300  -50.41900 -8.73000  1.000 44.68603  ? 62  PRO B C   1 
ATOM   4073 O O   . PRO B 1 62  ? -0.73500  -50.11900 -9.22800  1.000 44.27094  ? 62  PRO B O   1 
ATOM   4074 C CB  . PRO B 1 62  ? -1.79500  -52.23500 -6.97100  1.000 46.95361  ? 62  PRO B CB  1 
ATOM   4075 C CG  . PRO B 1 62  ? -0.48600  -52.93300 -7.08800  1.000 44.74926  ? 62  PRO B CG  1 
ATOM   4076 C CD  . PRO B 1 62  ? -0.54100  -53.66200 -8.39800  1.000 45.06779  ? 62  PRO B CD  1 
ATOM   4077 N N   . VAL B 1 63  ? -2.76100  -49.52000 -8.43200  1.000 46.47337  ? 63  VAL B N   1 
ATOM   4078 C CA  . VAL B 1 63  ? -2.63900  -48.14400 -8.90100  1.000 48.07763  ? 63  VAL B CA  1 
ATOM   4079 C C   . VAL B 1 63  ? -1.51800  -47.42000 -8.17000  1.000 52.14345  ? 63  VAL B C   1 
ATOM   4080 O O   . VAL B 1 63  ? -0.83700  -46.56300 -8.75800  1.000 47.87200  ? 63  VAL B O   1 
ATOM   4081 C CB  . VAL B 1 63  ? -3.99100  -47.42500 -8.75300  1.000 45.94013  ? 63  VAL B CB  1 
ATOM   4082 C CG1 . VAL B 1 63  ? -4.33900  -47.24000 -7.28100  1.000 54.27353  ? 63  VAL B CG1 1 
ATOM   4083 C CG2 . VAL B 1 63  ? -3.97800  -46.11100 -9.47800  1.000 40.66435  ? 63  VAL B CG2 1 
ATOM   4084 N N   . GLY B 1 64  ? -1.28900  -47.76400 -6.89300  1.000 53.26951  ? 64  GLY B N   1 
ATOM   4085 C CA  . GLY B 1 64  ? -0.18000  -47.18400 -6.15500  1.000 50.12599  ? 64  GLY B CA  1 
ATOM   4086 C C   . GLY B 1 64  ? 1.17200   -47.53200 -6.74600  1.000 54.70501  ? 64  GLY B C   1 
ATOM   4087 O O   . GLY B 1 64  ? 2.12800   -46.76100 -6.62300  1.000 63.53789  ? 64  GLY B O   1 
ATOM   4088 N N   . ARG B 1 65  ? 1.27500   -48.68100 -7.40500  1.000 50.99120  ? 65  ARG B N   1 
ATOM   4089 C CA  . ARG B 1 65  ? 2.49200   -49.07300 -8.10100  1.000 49.70955  ? 65  ARG B CA  1 
ATOM   4090 C C   . ARG B 1 65  ? 2.53800   -48.58800 -9.55200  1.000 50.40376  ? 65  ARG B C   1 
ATOM   4091 O O   . ARG B 1 65  ? 3.36100   -49.07800 -10.32900 1.000 56.00604  ? 65  ARG B O   1 
ATOM   4092 C CB  . ARG B 1 65  ? 2.64500   -50.59800 -8.06600  1.000 54.84079  ? 65  ARG B CB  1 
ATOM   4093 C CG  . ARG B 1 65  ? 3.50600   -51.14700 -6.93200  1.000 62.12538  ? 65  ARG B CG  1 
ATOM   4094 C CD  . ARG B 1 65  ? 3.04600   -50.63600 -5.57000  1.000 70.25726  ? 65  ARG B CD  1 
ATOM   4095 N NE  . ARG B 1 65  ? 3.36400   -51.55500 -4.47900  1.000 81.84084  ? 65  ARG B NE  1 
ATOM   4096 C CZ  . ARG B 1 65  ? 2.45900   -52.23200 -3.78000  1.000 80.37825  ? 65  ARG B CZ  1 
ATOM   4097 N NH1 . ARG B 1 65  ? 1.16500   -52.12700 -4.04200  1.000 68.62737  ? 65  ARG B NH1 1 
ATOM   4098 N NH2 . ARG B 1 65  ? 2.86100   -53.02500 -2.78800  1.000 79.07832  ? 65  ARG B NH2 1 
ATOM   4099 N N   . VAL B 1 66  ? 1.66900   -47.66000 -9.95000  1.000 54.10492  ? 66  VAL B N   1 
ATOM   4100 C CA  . VAL B 1 66  ? 1.58800   -47.29000 -11.36100 1.000 46.84356  ? 66  VAL B CA  1 
ATOM   4101 C C   . VAL B 1 66  ? 1.58600   -45.77400 -11.50700 1.000 45.87144  ? 66  VAL B C   1 
ATOM   4102 O O   . VAL B 1 66  ? 2.38300   -45.21900 -12.27200 1.000 48.09094  ? 66  VAL B O   1 
ATOM   4103 C CB  . VAL B 1 66  ? 0.36000   -47.93600 -12.03400 1.000 45.70475  ? 66  VAL B CB  1 
ATOM   4104 C CG1 . VAL B 1 66  ? -0.14300  -47.09400 -13.21400 1.000 44.20359  ? 66  VAL B CG1 1 
ATOM   4105 C CG2 . VAL B 1 66  ? 0.70700   -49.34900 -12.50700 1.000 42.87446  ? 66  VAL B CG2 1 
ATOM   4106 N N   . LEU B 1 67  ? 0.70100   -45.08400 -10.77100 1.000 42.86156  ? 67  LEU B N   1 
ATOM   4107 C CA  . LEU B 1 67  ? 0.67100   -43.63000 -10.88300 1.000 44.36096  ? 67  LEU B CA  1 
ATOM   4108 C C   . LEU B 1 67  ? 1.71900   -42.99400 -9.97700  1.000 46.18627  ? 67  LEU B C   1 
ATOM   4109 O O   . LEU B 1 67  ? 2.07300   -43.54700 -8.93300  1.000 46.77586  ? 67  LEU B O   1 
ATOM   4110 C CB  . LEU B 1 67  ? -0.69900  -43.07800 -10.50400 1.000 43.00967  ? 67  LEU B CB  1 
ATOM   4111 C CG  . LEU B 1 67  ? -1.90700  -43.37100 -11.38300 1.000 43.45316  ? 67  LEU B CG  1 
ATOM   4112 C CD1 . LEU B 1 67  ? -3.13500  -42.90200 -10.64200 1.000 41.06595  ? 67  LEU B CD1 1 
ATOM   4113 C CD2 . LEU B 1 67  ? -1.79900  -42.67100 -12.72800 1.000 39.28038  ? 67  LEU B CD2 1 
ATOM   4114 N N   . PRO B 1 68  ? 2.21400   -41.81900 -10.33500 1.000 52.37686  ? 68  PRO B N   1 
ATOM   4115 C CA  . PRO B 1 68  ? 3.15700   -41.13800 -9.45300  1.000 52.20646  ? 68  PRO B CA  1 
ATOM   4116 C C   . PRO B 1 68  ? 2.42500   -40.54900 -8.25800  1.000 49.19234  ? 68  PRO B C   1 
ATOM   4117 O O   . PRO B 1 68  ? 1.21400   -40.32000 -8.28600  1.000 46.36951  ? 68  PRO B O   1 
ATOM   4118 C CB  . PRO B 1 68  ? 3.76300   -40.04800 -10.34400 1.000 51.69523  ? 68  PRO B CB  1 
ATOM   4119 C CG  . PRO B 1 68  ? 3.27000   -40.35700 -11.76100 1.000 47.64725  ? 68  PRO B CG  1 
ATOM   4120 C CD  . PRO B 1 68  ? 1.95800   -41.03600 -11.55400 1.000 52.06938  ? 68  PRO B CD  1 
ATOM   4121 N N   . ALA B 1 69  ? 3.18700   -40.31200 -7.18800  1.000 50.93727  ? 69  ALA B N   1 
ATOM   4122 C CA  . ALA B 1 69  ? 2.58300   -39.84100 -5.94500  1.000 51.95511  ? 69  ALA B CA  1 
ATOM   4123 C C   . ALA B 1 69  ? 1.86500   -38.51100 -6.13400  1.000 51.76876  ? 69  ALA B C   1 
ATOM   4124 O O   . ALA B 1 69  ? 0.93100   -38.19700 -5.37900  1.000 45.94668  ? 69  ALA B O   1 
ATOM   4125 C CB  . ALA B 1 69  ? 3.65000   -39.72800 -4.85700  1.000 53.14261  ? 69  ALA B CB  1 
ATOM   4126 N N   . GLU B 1 70  ? 2.28400   -37.72200 -7.13000  1.000 50.20522  ? 70  GLU B N   1 
ATOM   4127 C CA  . GLU B 1 70  ? 1.59300   -36.47400 -7.43600  1.000 52.12802  ? 70  GLU B CA  1 
ATOM   4128 C C   . GLU B 1 70  ? 0.11200   -36.72100 -7.69300  1.000 55.25542  ? 70  GLU B C   1 
ATOM   4129 O O   . GLU B 1 70  ? -0.75000  -36.03700 -7.13000  1.000 52.30316  ? 70  GLU B O   1 
ATOM   4130 C CB  . GLU B 1 70  ? 2.22800   -35.79200 -8.65200  1.000 51.41745  ? 70  GLU B CB  1 
ATOM   4131 C CG  . GLU B 1 70  ? 3.57000   -35.14000 -8.39900  1.000 54.44322  ? 70  GLU B CG  1 
ATOM   4132 C CD  . GLU B 1 70  ? 4.69400   -36.15500 -8.29900  1.000 55.82677  ? 70  GLU B CD  1 
ATOM   4133 O OE1 . GLU B 1 70  ? 4.60600   -37.19000 -8.99500  1.000 53.80620  ? 70  GLU B OE1 1 
ATOM   4134 O OE2 . GLU B 1 70  ? 5.66000   -35.92600 -7.52700  1.000 55.07048  ? 70  GLU B OE2 1 
ATOM   4135 N N   . VAL B 1 71  ? -0.19900  -37.70800 -8.54000  1.000 54.58137  ? 71  VAL B N   1 
ATOM   4136 C CA  . VAL B 1 71  ? -1.58700  -37.95200 -8.92200  1.000 48.74806  ? 71  VAL B CA  1 
ATOM   4137 C C   . VAL B 1 71  ? -2.34800  -38.59500 -7.77300  1.000 49.03402  ? 71  VAL B C   1 
ATOM   4138 O O   . VAL B 1 71  ? -3.41100  -38.11000 -7.36900  1.000 53.25020  ? 71  VAL B O   1 
ATOM   4139 C CB  . VAL B 1 71  ? -1.66100  -38.81500 -10.19600 1.000 49.19599  ? 71  VAL B CB  1 
ATOM   4140 C CG1 . VAL B 1 71  ? -3.12300  -39.09600 -10.55600 1.000 50.72074  ? 71  VAL B CG1 1 
ATOM   4141 C CG2 . VAL B 1 71  ? -0.91800  -38.14200 -11.35800 1.000 43.77587  ? 71  VAL B CG2 1 
ATOM   4142 N N   . LEU B 1 72  ? -1.82200  -39.70300 -7.23500  1.000 46.53082  ? 72  LEU B N   1 
ATOM   4143 C CA  . LEU B 1 72  ? -2.47100  -40.35100 -6.09600  1.000 49.86667  ? 72  LEU B CA  1 
ATOM   4144 C C   . LEU B 1 72  ? -2.72900  -39.37700 -4.95600  1.000 49.77040  ? 72  LEU B C   1 
ATOM   4145 O O   . LEU B 1 72  ? -3.74000  -39.49400 -4.25500  1.000 48.58435  ? 72  LEU B O   1 
ATOM   4146 C CB  . LEU B 1 72  ? -1.62300  -41.50500 -5.57000  1.000 42.38430  ? 72  LEU B CB  1 
ATOM   4147 C CG  . LEU B 1 72  ? -1.42100  -42.72100 -6.45500  1.000 45.16428  ? 72  LEU B CG  1 
ATOM   4148 C CD1 . LEU B 1 72  ? -0.44500  -43.65900 -5.76500  1.000 47.53145  ? 72  LEU B CD1 1 
ATOM   4149 C CD2 . LEU B 1 72  ? -2.74400  -43.40800 -6.73100  1.000 44.08829  ? 72  LEU B CD2 1 
ATOM   4150 N N   . ALA B 1 73  ? -1.83100  -38.41000 -4.75700  1.000 48.57869  ? 73  ALA B N   1 
ATOM   4151 C CA  . ALA B 1 73  ? -2.00600  -37.45700 -3.67100  1.000 48.00572  ? 73  ALA B CA  1 
ATOM   4152 C C   . ALA B 1 73  ? -3.35600  -36.75100 -3.74200  1.000 51.98644  ? 73  ALA B C   1 
ATOM   4153 O O   . ALA B 1 73  ? -3.91800  -36.38600 -2.70100  1.000 49.15671  ? 73  ALA B O   1 
ATOM   4154 C CB  . ALA B 1 73  ? -0.86900  -36.43400 -3.67800  1.000 44.26674  ? 73  ALA B CB  1 
ATOM   4155 N N   . GLN B 1 74  ? -3.90700  -36.56000 -4.94200  1.000 50.06849  ? 74  GLN B N   1 
ATOM   4156 C CA  . GLN B 1 74  ? -5.13800  -35.79600 -5.09200  1.000 50.18375  ? 74  GLN B CA  1 
ATOM   4157 C C   . GLN B 1 74  ? -6.33200  -36.67600 -5.46300  1.000 49.00371  ? 74  GLN B C   1 
ATOM   4158 O O   . GLN B 1 74  ? -7.28700  -36.21300 -6.10100  1.000 43.43573  ? 74  GLN B O   1 
ATOM   4159 C CB  . GLN B 1 74  ? -4.93700  -34.67600 -6.10900  1.000 51.63303  ? 74  GLN B CB  1 
ATOM   4160 C CG  . GLN B 1 74  ? -3.66700  -33.87700 -5.84500  1.000 58.13638  ? 74  GLN B CG  1 
ATOM   4161 C CD  . GLN B 1 74  ? -3.86000  -32.38700 -6.00200  1.000 62.46091  ? 74  GLN B CD  1 
ATOM   4162 O OE1 . GLN B 1 74  ? -4.88800  -31.83900 -5.59500  1.000 66.27366  ? 74  GLN B OE1 1 
ATOM   4163 N NE2 . GLN B 1 74  ? -2.87200  -31.71700 -6.60300  1.000 62.11823  ? 74  GLN B NE2 1 
ATOM   4164 N N   . TRP B 1 75  ? -6.31700  -37.93000 -5.00200  1.000 44.31050  ? 75  TRP B N   1 
ATOM   4165 C CA  . TRP B 1 75  ? -7.33200  -38.89400 -5.41200  1.000 43.97672  ? 75  TRP B CA  1 
ATOM   4166 C C   . TRP B 1 75  ? -8.73100  -38.50700 -4.93700  1.000 47.09847  ? 75  TRP B C   1 
ATOM   4167 O O   . TRP B 1 75  ? -9.70700  -38.67800 -5.67700  1.000 48.84636  ? 75  TRP B O   1 
ATOM   4168 C CB  . TRP B 1 75  ? -6.96400  -40.27100 -4.89100  1.000 46.58776  ? 75  TRP B CB  1 
ATOM   4169 C CG  . TRP B 1 75  ? -7.70400  -41.31000 -5.58400  1.000 51.44477  ? 75  TRP B CG  1 
ATOM   4170 C CD1 . TRP B 1 75  ? -8.80100  -41.96600 -5.13600  1.000 52.67062  ? 75  TRP B CD1 1 
ATOM   4171 C CD2 . TRP B 1 75  ? -7.43300  -41.81500 -6.89400  1.000 48.88193  ? 75  TRP B CD2 1 
ATOM   4172 N NE1 . TRP B 1 75  ? -9.22800  -42.86900 -6.08100  1.000 57.65392  ? 75  TRP B NE1 1 
ATOM   4173 C CE2 . TRP B 1 75  ? -8.40400  -42.79100 -7.17200  1.000 48.23743  ? 75  TRP B CE2 1 
ATOM   4174 C CE3 . TRP B 1 75  ? -6.46100  -41.54100 -7.85200  1.000 47.09903  ? 75  TRP B CE3 1 
ATOM   4175 C CZ2 . TRP B 1 75  ? -8.43300  -43.49200 -8.36700  1.000 48.60223  ? 75  TRP B CZ2 1 
ATOM   4176 C CZ3 . TRP B 1 75  ? -6.49000  -42.24100 -9.04000  1.000 51.59909  ? 75  TRP B CZ3 1 
ATOM   4177 C CH2 . TRP B 1 75  ? -7.46900  -43.20700 -9.28800  1.000 52.12225  ? 75  TRP B CH2 1 
ATOM   4178 N N   . GLU B 1 76  ? -8.86000  -37.99900 -3.70400  1.000 47.63186  ? 76  GLU B N   1 
ATOM   4179 C CA  . GLU B 1 76  ? -10.20000 -37.75000 -3.16700  1.000 50.05008  ? 76  GLU B CA  1 
ATOM   4180 C C   . GLU B 1 76  ? -10.90400 -36.59600 -3.87300  1.000 46.26673  ? 76  GLU B C   1 
ATOM   4181 O O   . GLU B 1 76  ? -12.07600 -36.76200 -4.25900  1.000 46.78773  ? 76  GLU B O   1 
ATOM   4182 C CB  . GLU B 1 76  ? -10.13100 -37.52800 -1.65100  1.000 47.89699  ? 76  GLU B CB  1 
ATOM   4183 C CG  . GLU B 1 76  ? -9.24700  -38.50300 -0.87400  1.000 55.03591  ? 76  GLU B CG  1 
ATOM   4184 C CD  . GLU B 1 76  ? -9.16400  -38.16100 0.62700   1.000 69.13543  ? 76  GLU B CD  1 
ATOM   4185 O OE1 . GLU B 1 76  ? -10.00600 -37.36200 1.11400   1.000 66.93288  ? 76  GLU B OE1 1 
ATOM   4186 O OE2 . GLU B 1 76  ? -8.25200  -38.68600 1.31900   1.000 69.24007  ? 76  GLU B OE2 1 
ATOM   4187 N N   . PRO B 1 77  ? -10.28800 -35.42000 -4.06900  1.000 45.19436  ? 77  PRO B N   1 
ATOM   4188 C CA  . PRO B 1 77  ? -10.98200 -34.38300 -4.84600  1.000 46.97763  ? 77  PRO B CA  1 
ATOM   4189 C C   . PRO B 1 77  ? -11.12200 -34.77800 -6.30100  1.000 50.39193  ? 77  PRO B C   1 
ATOM   4190 O O   . PRO B 1 77  ? -12.09400 -34.37700 -6.96100  1.000 48.75188  ? 77  PRO B O   1 
ATOM   4191 C CB  . PRO B 1 77  ? -10.09000 -33.14800 -4.66800  1.000 43.79396  ? 77  PRO B CB  1 
ATOM   4192 C CG  . PRO B 1 77  ? -8.72400  -33.71600 -4.47600  1.000 46.01420  ? 77  PRO B CG  1 
ATOM   4193 C CD  . PRO B 1 77  ? -8.91600  -35.00400 -3.71600  1.000 45.17247  ? 77  PRO B CD  1 
ATOM   4194 N N   . LEU B 1 78  ? -10.17300 -35.56900 -6.80900  1.000 43.77070  ? 78  LEU B N   1 
ATOM   4195 C CA  . LEU B 1 78  ? -10.34700 -36.18800 -8.11300  1.000 43.70619  ? 78  LEU B CA  1 
ATOM   4196 C C   . LEU B 1 78  ? -11.66300 -36.95300 -8.16600  1.000 48.26673  ? 78  LEU B C   1 
ATOM   4197 O O   . LEU B 1 78  ? -12.47700 -36.74900 -9.07600  1.000 45.82461  ? 78  LEU B O   1 
ATOM   4198 C CB  . LEU B 1 78  ? -9.17000  -37.11000 -8.42400  1.000 36.69867  ? 78  LEU B CB  1 
ATOM   4199 C CG  . LEU B 1 78  ? -9.23700  -37.57400 -9.87500  1.000 37.37823  ? 78  LEU B CG  1 
ATOM   4200 C CD1 . LEU B 1 78  ? -9.27300  -36.34500 -10.77800 1.000 35.79224  ? 78  LEU B CD1 1 
ATOM   4201 C CD2 . LEU B 1 78  ? -8.06800  -38.48200 -10.22800 1.000 38.87737  ? 78  LEU B CD2 1 
ATOM   4202 N N   . VAL B 1 79  ? -11.89800 -37.81700 -7.16800  1.000 47.68555  ? 79  VAL B N   1 
ATOM   4203 C CA  . VAL B 1 79  ? -13.12400 -38.61400 -7.12900  1.000 47.38622  ? 79  VAL B CA  1 
ATOM   4204 C C   . VAL B 1 79  ? -14.32800 -37.73600 -6.83900  1.000 47.23727  ? 79  VAL B C   1 
ATOM   4205 O O   . VAL B 1 79  ? -15.36900 -37.85100 -7.49500  1.000 54.51516  ? 79  VAL B O   1 
ATOM   4206 C CB  . VAL B 1 79  ? -13.00500 -39.73600 -6.09000  1.000 48.06010  ? 79  VAL B CB  1 
ATOM   4207 C CG1 . VAL B 1 79  ? -14.34300 -40.41100 -5.93100  1.000 51.61022  ? 79  VAL B CG1 1 
ATOM   4208 C CG2 . VAL B 1 79  ? -11.93700 -40.72800 -6.52000  1.000 49.38637  ? 79  VAL B CG2 1 
ATOM   4209 N N   . ALA B 1 80  ? -14.21900 -36.86900 -5.83500  1.000 47.95766  ? 80  ALA B N   1 
ATOM   4210 C CA  . ALA B 1 80  ? -15.31800 -35.96100 -5.53800  1.000 50.39141  ? 80  ALA B CA  1 
ATOM   4211 C C   . ALA B 1 80  ? -15.60200 -35.06700 -6.73600  1.000 48.17149  ? 80  ALA B C   1 
ATOM   4212 O O   . ALA B 1 80  ? -16.59900 -35.26400 -7.44000  1.000 54.07734  ? 80  ALA B O   1 
ATOM   4213 C CB  . ALA B 1 80  ? -15.01500 -35.11000 -4.30400  1.000 47.21502  ? 80  ALA B CB  1 
ATOM   4214 N N   . ARG B 1 81  ? -14.72200 -34.10300 -6.99300  1.000 48.31203  ? 81  ARG B N   1 
ATOM   4215 C CA  . ARG B 1 81  ? -15.02700 -33.04700 -7.94700  1.000 52.96818  ? 81  ARG B CA  1 
ATOM   4216 C C   . ARG B 1 81  ? -14.84400 -33.46200 -9.40400  1.000 53.30040  ? 81  ARG B C   1 
ATOM   4217 O O   . ARG B 1 81  ? -15.15800 -32.66800 -10.30100 1.000 57.91567  ? 81  ARG B O   1 
ATOM   4218 C CB  . ARG B 1 81  ? -14.18400 -31.80800 -7.63400  1.000 51.40173  ? 81  ARG B CB  1 
ATOM   4219 C CG  . ARG B 1 81  ? -14.79300 -30.93600 -6.53900  1.000 63.15616  ? 81  ARG B CG  1 
ATOM   4220 C CD  . ARG B 1 81  ? -14.13700 -29.56600 -6.45700  1.000 73.67799  ? 81  ARG B CD  1 
ATOM   4221 N NE  . ARG B 1 81  ? -12.68300 -29.68000 -6.43100  1.000 80.32174  ? 81  ARG B NE  1 
ATOM   4222 C CZ  . ARG B 1 81  ? -11.89200 -29.45700 -7.47500  1.000 79.45958  ? 81  ARG B CZ  1 
ATOM   4223 N NH1 . ARG B 1 81  ? -12.37900 -29.04600 -8.64200  1.000 70.88297  ? 81  ARG B NH1 1 
ATOM   4224 N NH2 . ARG B 1 81  ? -10.58000 -29.65600 -7.34700  1.000 68.96712  ? 81  ARG B NH2 1 
ATOM   4225 N N   . GLY B 1 82  ? -14.35200 -34.66900 -9.67300  1.000 48.33423  ? 82  GLY B N   1 
ATOM   4226 C CA  . GLY B 1 82  ? -14.23000 -35.15200 -11.02600 1.000 44.54223  ? 82  GLY B CA  1 
ATOM   4227 C C   . GLY B 1 82  ? -12.94800 -34.78000 -11.74400 1.000 44.53603  ? 82  GLY B C   1 
ATOM   4228 O O   . GLY B 1 82  ? -12.58500 -35.47200 -12.70300 1.000 43.97995  ? 82  GLY B O   1 
ATOM   4229 N N   . SER B 1 83  ? -12.25500 -33.70900 -11.33200 1.000 45.54694  ? 83  SER B N   1 
ATOM   4230 C CA  . SER B 1 83  ? -10.98900 -33.34500 -11.97400 1.000 42.31000  ? 83  SER B CA  1 
ATOM   4231 C C   . SER B 1 83  ? -10.11800 -32.50400 -11.04100 1.000 41.30811  ? 83  SER B C   1 
ATOM   4232 O O   . SER B 1 83  ? -10.62900 -31.76500 -10.19900 1.000 46.12836  ? 83  SER B O   1 
ATOM   4233 C CB  . SER B 1 83  ? -11.23100 -32.58500 -13.27900 1.000 38.96153  ? 83  SER B CB  1 
ATOM   4234 O OG  . SER B 1 83  ? -10.95000 -31.20700 -13.13200 1.000 46.41666  ? 83  SER B OG  1 
ATOM   4235 N N   . VAL B 1 84  ? -8.79600  -32.61200 -11.22100 1.000 36.72192  ? 84  VAL B N   1 
ATOM   4236 C CA  . VAL B 1 84  ? -7.80800  -31.82600 -10.47800 1.000 36.29524  ? 84  VAL B CA  1 
ATOM   4237 C C   . VAL B 1 84  ? -6.64600  -31.44500 -11.38700 1.000 39.30992  ? 84  VAL B C   1 
ATOM   4238 O O   . VAL B 1 84  ? -6.30300  -32.16900 -12.32700 1.000 39.95599  ? 84  VAL B O   1 
ATOM   4239 C CB  . VAL B 1 84  ? -7.22100  -32.57300 -9.26000  1.000 32.99584  ? 84  VAL B CB  1 
ATOM   4240 C CG1 . VAL B 1 84  ? -8.24500  -32.74800 -8.15900  1.000 39.24138  ? 84  VAL B CG1 1 
ATOM   4241 C CG2 . VAL B 1 84  ? -6.67000  -33.88700 -9.70300  1.000 32.96437  ? 84  VAL B CG2 1 
ATOM   4242 N N   . ARG B 1 85  ? -6.01100  -30.31200 -11.07900 1.000 41.43900  ? 85  ARG B N   1 
ATOM   4243 C CA  . ARG B 1 85  ? -4.73300  -29.94700 -11.68600 1.000 38.37653  ? 85  ARG B CA  1 
ATOM   4244 C C   . ARG B 1 85  ? -3.60800  -30.60500 -10.88900 1.000 39.47176  ? 85  ARG B C   1 
ATOM   4245 O O   . ARG B 1 85  ? -3.48600  -30.37500 -9.68100  1.000 45.99953  ? 85  ARG B O   1 
ATOM   4246 C CB  . ARG B 1 85  ? -4.55200  -28.43100 -11.70400 1.000 38.57316  ? 85  ARG B CB  1 
ATOM   4247 C CG  . ARG B 1 85  ? -3.20800  -27.98400 -12.23400 1.000 46.37579  ? 85  ARG B CG  1 
ATOM   4248 C CD  . ARG B 1 85  ? -2.85500  -26.56300 -11.80500 1.000 50.83668  ? 85  ARG B CD  1 
ATOM   4249 N NE  . ARG B 1 85  ? -1.83800  -25.99900 -12.68400 1.000 47.41210  ? 85  ARG B NE  1 
ATOM   4250 C CZ  . ARG B 1 85  ? -2.10800  -25.45500 -13.86400 1.000 51.14347  ? 85  ARG B CZ  1 
ATOM   4251 N NH1 . ARG B 1 85  ? -3.35200  -25.36600 -14.31500 1.000 45.43620  ? 85  ARG B NH1 1 
ATOM   4252 N NH2 . ARG B 1 85  ? -1.10600  -24.99100 -14.61100 1.000 49.27351  ? 85  ARG B NH2 1 
ATOM   4253 N N   . VAL B 1 86  ? -2.79900  -31.43100 -11.54700 1.000 35.67688  ? 86  VAL B N   1 
ATOM   4254 C CA  . VAL B 1 86  ? -1.59700  -31.98800 -10.94200 1.000 46.00528  ? 86  VAL B CA  1 
ATOM   4255 C C   . VAL B 1 86  ? -0.38200  -31.42900 -11.67000 1.000 45.01502  ? 86  VAL B C   1 
ATOM   4256 O O   . VAL B 1 86  ? -0.41900  -31.21400 -12.88600 1.000 45.03126  ? 86  VAL B O   1 
ATOM   4257 C CB  . VAL B 1 86  ? -1.57600  -33.53100 -10.95500 1.000 42.93385  ? 86  VAL B CB  1 
ATOM   4258 C CG1 . VAL B 1 86  ? -2.70000  -34.08000 -10.10200 1.000 51.05883  ? 86  VAL B CG1 1 
ATOM   4259 C CG2 . VAL B 1 86  ? -1.65600  -34.05600 -12.36000 1.000 44.28106  ? 86  VAL B CG2 1 
ATOM   4260 N N   . VAL B 1 87  ? 0.68800   -31.18200 -10.91600 1.000 41.55956  ? 87  VAL B N   1 
ATOM   4261 C CA  . VAL B 1 87  ? 1.96400   -30.72300 -11.44900 1.000 46.98237  ? 87  VAL B CA  1 
ATOM   4262 C C   . VAL B 1 87  ? 2.91300   -31.90900 -11.39200 1.000 53.03442  ? 87  VAL B C   1 
ATOM   4263 O O   . VAL B 1 87  ? 3.29000   -32.36900 -10.30600 1.000 54.74909  ? 87  VAL B O   1 
ATOM   4264 C CB  . VAL B 1 87  ? 2.52500   -29.52100 -10.67400 1.000 46.20536  ? 87  VAL B CB  1 
ATOM   4265 C CG1 . VAL B 1 87  ? 3.85300   -29.10700 -11.26600 1.000 39.86573  ? 87  VAL B CG1 1 
ATOM   4266 C CG2 . VAL B 1 87  ? 1.54300   -28.34900 -10.70400 1.000 39.88215  ? 87  VAL B CG2 1 
ATOM   4267 N N   . LEU B 1 88  ? 3.27400   -32.41400 -12.55800 1.000 47.27654  ? 88  LEU B N   1 
ATOM   4268 C CA  . LEU B 1 88  ? 4.15700   -33.54400 -12.74300 1.000 47.82739  ? 88  LEU B CA  1 
ATOM   4269 C C   . LEU B 1 88  ? 5.47600   -33.05000 -13.30900 1.000 56.12936  ? 88  LEU B C   1 
ATOM   4270 O O   . LEU B 1 88  ? 5.57100   -31.91100 -13.78000 1.000 55.25675  ? 88  LEU B O   1 
ATOM   4271 C CB  . LEU B 1 88  ? 3.50500   -34.55700 -13.69300 1.000 51.10161  ? 88  LEU B CB  1 
ATOM   4272 C CG  . LEU B 1 88  ? 2.27600   -35.27500 -13.13800 1.000 50.65974  ? 88  LEU B CG  1 
ATOM   4273 C CD1 . LEU B 1 88  ? 1.51200   -35.95200 -14.25700 1.000 41.16168  ? 88  LEU B CD1 1 
ATOM   4274 C CD2 . LEU B 1 88  ? 2.70600   -36.28500 -12.09400 1.000 48.86854  ? 88  LEU B CD2 1 
ATOM   4275 N N   . PRO B 1 89  ? 6.53300   -33.87600 -13.27600 1.000 60.34239  ? 89  PRO B N   1 
ATOM   4276 C CA  . PRO B 1 89  ? 7.80600   -33.43300 -13.87000 1.000 56.82342  ? 89  PRO B CA  1 
ATOM   4277 C C   . PRO B 1 89  ? 7.65900   -33.00800 -15.31500 1.000 56.00997  ? 89  PRO B C   1 
ATOM   4278 O O   . PRO B 1 89  ? 8.33100   -32.06500 -15.75400 1.000 62.91046  ? 89  PRO B O   1 
ATOM   4279 C CB  . PRO B 1 89  ? 8.71100   -34.66900 -13.73300 1.000 53.44685  ? 89  PRO B CB  1 
ATOM   4280 C CG  . PRO B 1 89  ? 7.76800   -35.82300 -13.59900 1.000 51.65890  ? 89  PRO B CG  1 
ATOM   4281 C CD  . PRO B 1 89  ? 6.61900   -35.27200 -12.80300 1.000 58.96266  ? 89  PRO B CD  1 
ATOM   4282 N N   . ALA B 1 90  ? 6.76800   -33.66400 -16.06000 1.000 54.99169  ? 90  ALA B N   1 
ATOM   4283 C CA  . ALA B 1 90  ? 6.52900   -33.29700 -17.44600 1.000 50.71260  ? 90  ALA B CA  1 
ATOM   4284 C C   . ALA B 1 90  ? 5.83300   -31.95000 -17.58000 1.000 56.65239  ? 90  ALA B C   1 
ATOM   4285 O O   . ALA B 1 90  ? 5.83900   -31.37600 -18.67600 1.000 52.76008  ? 90  ALA B O   1 
ATOM   4286 C CB  . ALA B 1 90  ? 5.70300   -34.38100 -18.13900 1.000 54.01201  ? 90  ALA B CB  1 
ATOM   4287 N N   . GLY B 1 91  ? 5.23400   -31.44000 -16.50500 1.000 53.63250  ? 91  GLY B N   1 
ATOM   4288 C CA  . GLY B 1 91  ? 4.54000   -30.17000 -16.52600 1.000 46.07262  ? 91  GLY B CA  1 
ATOM   4289 C C   . GLY B 1 91  ? 3.13900   -30.28300 -15.96900 1.000 46.28754  ? 91  GLY B C   1 
ATOM   4290 O O   . GLY B 1 91  ? 2.70500   -31.33000 -15.49600 1.000 48.60380  ? 91  GLY B O   1 
ATOM   4291 N N   . ALA B 1 92  ? 2.42000   -29.16800 -16.03900 1.000 44.68321  ? 92  ALA B N   1 
ATOM   4292 C CA  . ALA B 1 92  ? 1.09200   -29.09600 -15.45100 1.000 43.33166  ? 92  ALA B CA  1 
ATOM   4293 C C   . ALA B 1 92  ? 0.08100   -29.84900 -16.31400 1.000 45.39766  ? 92  ALA B C   1 
ATOM   4294 O O   . ALA B 1 92  ? -0.02800  -29.60900 -17.52600 1.000 34.82027  ? 92  ALA B O   1 
ATOM   4295 C CB  . ALA B 1 92  ? 0.66900   -27.63600 -15.27300 1.000 44.08797  ? 92  ALA B CB  1 
ATOM   4296 N N   . TYR B 1 93  ? -0.67000  -30.74700 -15.66700 1.000 40.77729  ? 93  TYR B N   1 
ATOM   4297 C CA  . TYR B 1 93  ? -1.64000  -31.61500 -16.31300 1.000 37.94498  ? 93  TYR B CA  1 
ATOM   4298 C C   . TYR B 1 93  ? -2.96800  -31.54400 -15.58800 1.000 37.02962  ? 93  TYR B C   1 
ATOM   4299 O O   . TYR B 1 93  ? -3.02600  -31.31100 -14.37500 1.000 40.70152  ? 93  TYR B O   1 
ATOM   4300 C CB  . TYR B 1 93  ? -1.18100  -33.06700 -16.33700 1.000 33.07955  ? 93  TYR B CB  1 
ATOM   4301 C CG  . TYR B 1 93  ? -0.35200  -33.37100 -17.54200 1.000 36.89040  ? 93  TYR B CG  1 
ATOM   4302 C CD1 . TYR B 1 93  ? -0.94900  -33.74000 -18.74100 1.000 35.91332  ? 93  TYR B CD1 1 
ATOM   4303 C CD2 . TYR B 1 93  ? 1.03200   -33.27700 -17.49200 1.000 43.49237  ? 93  TYR B CD2 1 
ATOM   4304 C CE1 . TYR B 1 93  ? -0.18100  -34.00900 -19.86000 1.000 41.41864  ? 93  TYR B CE1 1 
ATOM   4305 C CE2 . TYR B 1 93  ? 1.80900   -33.54300 -18.59200 1.000 43.20422  ? 93  TYR B CE2 1 
ATOM   4306 C CZ  . TYR B 1 93  ? 1.20900   -33.91200 -19.77600 1.000 43.79056  ? 93  TYR B CZ  1 
ATOM   4307 O OH  . TYR B 1 93  ? 2.00900   -34.18000 -20.87500 1.000 47.73074  ? 93  TYR B OH  1 
ATOM   4308 N N   . ARG B 1 94  ? -4.03000  -31.74800 -16.35200 1.000 32.72077  ? 94  ARG B N   1 
ATOM   4309 C CA  . ARG B 1 94  ? -5.37600  -31.88600 -15.82000 1.000 34.29038  ? 94  ARG B CA  1 
ATOM   4310 C C   . ARG B 1 94  ? -5.71400  -33.36900 -15.81600 1.000 32.25609  ? 94  ARG B C   1 
ATOM   4311 O O   . ARG B 1 94  ? -5.57800  -34.04500 -16.84800 1.000 31.85405  ? 94  ARG B O   1 
ATOM   4312 C CB  . ARG B 1 94  ? -6.37700  -31.08200 -16.66200 1.000 32.34744  ? 94  ARG B CB  1 
ATOM   4313 C CG  . ARG B 1 94  ? -7.87700  -31.26000 -16.33300 1.000 39.63162  ? 94  ARG B CG  1 
ATOM   4314 C CD  . ARG B 1 94  ? -8.32800  -30.65900 -14.97900 1.000 39.91931  ? 94  ARG B CD  1 
ATOM   4315 N NE  . ARG B 1 94  ? -7.86200  -29.29500 -14.76100 1.000 39.13569  ? 94  ARG B NE  1 
ATOM   4316 C CZ  . ARG B 1 94  ? -8.20200  -28.54000 -13.72300 1.000 44.79517  ? 94  ARG B CZ  1 
ATOM   4317 N NH1 . ARG B 1 94  ? -9.08800  -28.94600 -12.82800 1.000 44.42130  ? 94  ARG B NH1 1 
ATOM   4318 N NH2 . ARG B 1 94  ? -7.61900  -27.35300 -13.56400 1.000 48.34454  ? 94  ARG B NH2 1 
ATOM   4319 N N   . ALA B 1 95  ? -6.12000  -33.87900 -14.65500 1.000 29.22360  ? 95  ALA B N   1 
ATOM   4320 C CA  . ALA B 1 95  ? -6.55100  -35.26100 -14.51900 1.000 28.01981  ? 95  ALA B CA  1 
ATOM   4321 C C   . ALA B 1 95  ? -8.07400  -35.31500 -14.43900 1.000 34.40335  ? 95  ALA B C   1 
ATOM   4322 O O   . ALA B 1 95  ? -8.68900  -34.57200 -13.66200 1.000 38.62194  ? 95  ALA B O   1 
ATOM   4323 C CB  . ALA B 1 95  ? -5.92200  -35.90600 -13.28700 1.000 24.07861  ? 95  ALA B CB  1 
ATOM   4324 N N   . LEU B 1 96  ? -8.67300  -36.21100 -15.22400 1.000 28.96810  ? 96  LEU B N   1 
ATOM   4325 C CA  . LEU B 1 96  ? -10.11700 -36.31100 -15.38400 1.000 29.89472  ? 96  LEU B CA  1 
ATOM   4326 C C   . LEU B 1 96  ? -10.55600 -37.74600 -15.13300 1.000 30.67717  ? 96  LEU B C   1 
ATOM   4327 O O   . LEU B 1 96  ? -10.09300 -38.67100 -15.81600 1.000 32.87887  ? 96  LEU B O   1 
ATOM   4328 C CB  . LEU B 1 96  ? -10.51900 -35.86500 -16.79100 1.000 32.05508  ? 96  LEU B CB  1 
ATOM   4329 C CG  . LEU B 1 96  ? -10.22900 -34.38400 -17.06500 1.000 34.92823  ? 96  LEU B CG  1 
ATOM   4330 C CD1 . LEU B 1 96  ? -9.91600  -34.14500 -18.53700 1.000 35.28970  ? 96  LEU B CD1 1 
ATOM   4331 C CD2 . LEU B 1 96  ? -11.42400 -33.54600 -16.64900 1.000 36.26483  ? 96  LEU B CD2 1 
ATOM   4332 N N   . LEU B 1 97  ? -11.45400 -37.93600 -14.16800 1.000 28.57606  ? 97  LEU B N   1 
ATOM   4333 C CA  . LEU B 1 97  ? -11.92700 -39.26000 -13.78100 1.000 29.02049  ? 97  LEU B CA  1 
ATOM   4334 C C   . LEU B 1 97  ? -13.38600 -39.45000 -14.19100 1.000 33.31994  ? 97  LEU B C   1 
ATOM   4335 O O   . LEU B 1 97  ? -14.22200 -38.58300 -13.92300 1.000 33.13241  ? 97  LEU B O   1 
ATOM   4336 C CB  . LEU B 1 97  ? -11.79600 -39.44900 -12.26700 1.000 29.90928  ? 97  LEU B CB  1 
ATOM   4337 C CG  . LEU B 1 97  ? -11.67400 -40.89900 -11.80600 1.000 34.19671  ? 97  LEU B CG  1 
ATOM   4338 C CD1 . LEU B 1 97  ? -10.27100 -41.41000 -12.16000 1.000 33.68040  ? 97  LEU B CD1 1 
ATOM   4339 C CD2 . LEU B 1 97  ? -11.96800 -41.07000 -10.31700 1.000 27.35071  ? 97  LEU B CD2 1 
ATOM   4340 N N   . HIS B 1 98  ? -13.70100 -40.58100 -14.82300 1.000 32.40660  ? 98  HIS B N   1 
ATOM   4341 C CA  . HIS B 1 98  ? -15.09500 -40.96700 -14.99900 1.000 30.59911  ? 98  HIS B CA  1 
ATOM   4342 C C   . HIS B 1 98  ? -15.18400 -42.49000 -14.96000 1.000 32.06213  ? 98  HIS B C   1 
ATOM   4343 O O   . HIS B 1 98  ? -14.17200 -43.19200 -14.84400 1.000 33.98882  ? 98  HIS B O   1 
ATOM   4344 C CB  . HIS B 1 98  ? -15.69500 -40.36700 -16.28300 1.000 25.95404  ? 98  HIS B CB  1 
ATOM   4345 C CG  . HIS B 1 98  ? -15.18800 -40.98600 -17.54700 1.000 28.51830  ? 98  HIS B CG  1 
ATOM   4346 N ND1 . HIS B 1 98  ? -13.96000 -40.67400 -18.09200 1.000 31.04387  ? 98  HIS B ND1 1 
ATOM   4347 C CD2 . HIS B 1 98  ? -15.74900 -41.89800 -18.38100 1.000 28.08898  ? 98  HIS B CD2 1 
ATOM   4348 C CE1 . HIS B 1 98  ? -13.78400 -41.36400 -19.20700 1.000 31.14778  ? 98  HIS B CE1 1 
ATOM   4349 N NE2 . HIS B 1 98  ? -14.85100 -42.12500 -19.40000 1.000 31.65642  ? 98  HIS B NE2 1 
ATOM   4350 N N   . GLU B 1 99  ? -16.41400 -42.99900 -15.00500 1.000 30.05737  ? 99  GLU B N   1 
ATOM   4351 C CA  . GLU B 1 99  ? -16.66500 -44.43400 -14.98400 1.000 36.84829  ? 99  GLU B CA  1 
ATOM   4352 C C   . GLU B 1 99  ? -17.26700 -44.89100 -16.30600 1.000 36.60711  ? 99  GLU B C   1 
ATOM   4353 O O   . GLU B 1 99  ? -18.18900 -44.25100 -16.83300 1.000 25.60755  ? 99  GLU B O   1 
ATOM   4354 C CB  . GLU B 1 99  ? -17.60100 -44.81500 -13.84700 1.000 39.57384  ? 99  GLU B CB  1 
ATOM   4355 C CG  . GLU B 1 99  ? -17.01000 -44.59600 -12.48400 1.000 44.50072  ? 99  GLU B CG  1 
ATOM   4356 C CD  . GLU B 1 99  ? -18.04200 -44.76500 -11.40600 1.000 57.30491  ? 99  GLU B CD  1 
ATOM   4357 O OE1 . GLU B 1 99  ? -19.06800 -45.43200 -11.67900 1.000 59.36032  ? 99  GLU B OE1 1 
ATOM   4358 O OE2 . GLU B 1 99  ? -17.83300 -44.22200 -10.29900 1.000 66.59309  ? 99  GLU B OE2 1 
ATOM   4359 N N   . SER B 1 100 ? -16.73900 -46.00700 -16.82700 1.000 30.36788  ? 100 SER B N   1 
ATOM   4360 C CA  . SER B 1 100 ? -17.21100 -46.59800 -18.06900 1.000 31.36092  ? 100 SER B CA  1 
ATOM   4361 C C   . SER B 1 100 ? -16.94200 -48.09300 -18.01800 1.000 36.56495  ? 100 SER B C   1 
ATOM   4362 O O   . SER B 1 100 ? -15.80900 -48.50900 -17.74500 1.000 32.30394  ? 100 SER B O   1 
ATOM   4363 C CB  . SER B 1 100 ? -16.52100 -45.96600 -19.28800 1.000 32.75163  ? 100 SER B CB  1 
ATOM   4364 O OG  . SER B 1 100 ? -16.90300 -46.60000 -20.50100 1.000 32.12186  ? 100 SER B OG  1 
ATOM   4365 N N   . ASP B 1 101 ? -17.99100 -48.88700 -18.26400 1.000 34.82372  ? 101 ASP B N   1 
ATOM   4366 C CA  . ASP B 1 101 ? -17.89000 -50.34500 -18.31800 1.000 32.56794  ? 101 ASP B CA  1 
ATOM   4367 C C   . ASP B 1 101 ? -17.41200 -50.93700 -16.98900 1.000 31.38184  ? 101 ASP B C   1 
ATOM   4368 O O   . ASP B 1 101 ? -16.67000 -51.91800 -16.95900 1.000 36.61617  ? 101 ASP B O   1 
ATOM   4369 C CB  . ASP B 1 101 ? -16.97800 -50.79000 -19.46400 1.000 32.44595  ? 101 ASP B CB  1 
ATOM   4370 C CG  . ASP B 1 101 ? -17.59700 -50.56300 -20.83100 1.000 36.61186  ? 101 ASP B CG  1 
ATOM   4371 O OD1 . ASP B 1 101 ? -18.84400 -50.46400 -20.90600 1.000 38.68235  ? 101 ASP B OD1 1 
ATOM   4372 O OD2 . ASP B 1 101 ? -16.84200 -50.50100 -21.83300 1.000 33.08607  ? 101 ASP B OD2 1 
ATOM   4373 N N   . GLY B 1 102 ? -17.84200 -50.35300 -15.87400 1.000 29.64641  ? 102 GLY B N   1 
ATOM   4374 C CA  . GLY B 1 102 ? -17.38700 -50.87400 -14.59900 1.000 31.15522  ? 102 GLY B CA  1 
ATOM   4375 C C   . GLY B 1 102 ? -15.90500 -50.68900 -14.34700 1.000 38.34426  ? 102 GLY B C   1 
ATOM   4376 O O   . GLY B 1 102 ? -15.33200 -51.36600 -13.48500 1.000 42.49912  ? 102 GLY B O   1 
ATOM   4377 N N   . LEU B 1 103 ? -15.26800 -49.79300 -15.09100 1.000 35.95015  ? 103 LEU B N   1 
ATOM   4378 C CA  . LEU B 1 103 ? -13.89200 -49.38500 -14.87400 1.000 36.38554  ? 103 LEU B CA  1 
ATOM   4379 C C   . LEU B 1 103 ? -13.86500 -47.92200 -14.45500 1.000 36.84781  ? 103 LEU B C   1 
ATOM   4380 O O   . LEU B 1 103 ? -14.79800 -47.15200 -14.74700 1.000 33.00459  ? 103 LEU B O   1 
ATOM   4381 C CB  . LEU B 1 103 ? -13.05900 -49.58500 -16.14700 1.000 33.69798  ? 103 LEU B CB  1 
ATOM   4382 C CG  . LEU B 1 103 ? -13.10900 -51.03400 -16.63700 1.000 35.44396  ? 103 LEU B CG  1 
ATOM   4383 C CD1 . LEU B 1 103 ? -12.25200 -51.25400 -17.87900 1.000 26.04239  ? 103 LEU B CD1 1 
ATOM   4384 C CD2 . LEU B 1 103 ? -12.71500 -51.99500 -15.50300 1.000 36.98721  ? 103 LEU B CD2 1 
ATOM   4385 N N   . THR B 1 104 ? -12.78400 -47.54000 -13.76500 1.000 33.96906  ? 104 THR B N   1 
ATOM   4386 C CA  . THR B 1 104 ? -12.52900 -46.14700 -13.40400 1.000 30.51464  ? 104 THR B CA  1 
ATOM   4387 C C   . THR B 1 104 ? -11.53200 -45.55300 -14.40200 1.000 33.14615  ? 104 THR B C   1 
ATOM   4388 O O   . THR B 1 104 ? -10.32900 -45.84200 -14.34600 1.000 32.66613  ? 104 THR B O   1 
ATOM   4389 C CB  . THR B 1 104 ? -12.01900 -46.05100 -11.96800 1.000 34.39148  ? 104 THR B CB  1 
ATOM   4390 O OG1 . THR B 1 104 ? -13.10900 -46.30900 -11.07600 1.000 29.02926  ? 104 THR B OG1 1 
ATOM   4391 C CG2 . THR B 1 104 ? -11.47700 -44.65800 -11.67700 1.000 28.12076  ? 104 THR B CG2 1 
ATOM   4392 N N   . VAL B 1 105 ? -12.03400 -44.73200 -15.32000 1.000 27.61703  ? 105 VAL B N   1 
ATOM   4393 C CA  . VAL B 1 105 ? -11.21600 -44.15200 -16.37500 1.000 31.03208  ? 105 VAL B CA  1 
ATOM   4394 C C   . VAL B 1 105 ? -10.52100 -42.90000 -15.85000 1.000 30.76313  ? 105 VAL B C   1 
ATOM   4395 O O   . VAL B 1 105 ? -11.16300 -41.99500 -15.30000 1.000 31.55602  ? 105 VAL B O   1 
ATOM   4396 C CB  . VAL B 1 105 ? -12.06400 -43.82300 -17.61400 1.000 32.30000  ? 105 VAL B CB  1 
ATOM   4397 C CG1 . VAL B 1 105 ? -11.15000 -43.40800 -18.76700 1.000 26.80608  ? 105 VAL B CG1 1 
ATOM   4398 C CG2 . VAL B 1 105 ? -12.90100 -45.01500 -18.00500 1.000 22.89154  ? 105 VAL B CG2 1 
ATOM   4399 N N   . LEU B 1 106 ? -9.20700  -42.85100 -16.02500 1.000 30.59170  ? 106 LEU B N   1 
ATOM   4400 C CA  . LEU B 1 106 ? -8.38400  -41.70300 -15.67500 1.000 29.67115  ? 106 LEU B CA  1 
ATOM   4401 C C   . LEU B 1 106 ? -7.73300  -41.17600 -16.94700 1.000 28.42527  ? 106 LEU B C   1 
ATOM   4402 O O   . LEU B 1 106 ? -7.04700  -41.92600 -17.64800 1.000 26.84621  ? 106 LEU B O   1 
ATOM   4403 C CB  . LEU B 1 106 ? -7.32000  -42.09800 -14.65500 1.000 31.36564  ? 106 LEU B CB  1 
ATOM   4404 C CG  . LEU B 1 106 ? -6.28200  -41.00800 -14.37000 1.000 34.84112  ? 106 LEU B CG  1 
ATOM   4405 C CD1 . LEU B 1 106 ? -6.95500  -39.85000 -13.65500 1.000 34.90097  ? 106 LEU B CD1 1 
ATOM   4406 C CD2 . LEU B 1 106 ? -5.12300  -41.56600 -13.55900 1.000 35.08721  ? 106 LEU B CD2 1 
ATOM   4407 N N   . GLU B 1 107 ? -7.96000  -39.89800 -17.25300 1.000 28.15999  ? 107 GLU B N   1 
ATOM   4408 C CA  . GLU B 1 107 ? -7.38100  -39.25400 -18.42500 1.000 27.79838  ? 107 GLU B CA  1 
ATOM   4409 C C   . GLU B 1 107 ? -6.54100  -38.06100 -17.98800 1.000 33.55981  ? 107 GLU B C   1 
ATOM   4410 O O   . GLU B 1 107 ? -6.93800  -37.30200 -17.09500 1.000 29.91328  ? 107 GLU B O   1 
ATOM   4411 C CB  . GLU B 1 107 ? -8.46000  -38.79300 -19.40100 1.000 20.79128  ? 107 GLU B CB  1 
ATOM   4412 C CG  . GLU B 1 107 ? -9.31000  -39.91000 -19.95400 1.000 32.77562  ? 107 GLU B CG  1 
ATOM   4413 C CD  . GLU B 1 107 ? -10.35500 -39.40000 -20.95800 1.000 35.05696  ? 107 GLU B CD  1 
ATOM   4414 O OE1 . GLU B 1 107 ? -11.32600 -38.74300 -20.51200 1.000 30.61045  ? 107 GLU B OE1 1 
ATOM   4415 O OE2 . GLU B 1 107 ? -10.18000 -39.63000 -22.18500 1.000 28.45652  ? 107 GLU B OE2 1 
ATOM   4416 N N   . LEU B 1 108 ? -5.38400  -37.89800 -18.63200 1.000 32.01435  ? 108 LEU B N   1 
ATOM   4417 C CA  . LEU B 1 108 ? -4.43300  -36.83500 -18.33300 1.000 30.62472  ? 108 LEU B CA  1 
ATOM   4418 C C   . LEU B 1 108 ? -4.11400  -36.08400 -19.61800 1.000 31.71488  ? 108 LEU B C   1 
ATOM   4419 O O   . LEU B 1 108 ? -3.60600  -36.68600 -20.57000 1.000 30.69987  ? 108 LEU B O   1 
ATOM   4420 C CB  . LEU B 1 108 ? -3.15800  -37.42000 -17.72500 1.000 34.60328  ? 108 LEU B CB  1 
ATOM   4421 C CG  . LEU B 1 108 ? -3.34700  -38.03900 -16.33300 1.000 40.34823  ? 108 LEU B CG  1 
ATOM   4422 C CD1 . LEU B 1 108 ? -2.31000  -39.10400 -16.04700 1.000 39.29855  ? 108 LEU B CD1 1 
ATOM   4423 C CD2 . LEU B 1 108 ? -3.26700  -36.96400 -15.27300 1.000 35.99898  ? 108 LEU B CD2 1 
ATOM   4424 N N   . GLU B 1 109 ? -4.41000  -34.78600 -19.65200 1.000 27.77240  ? 109 GLU B N   1 
ATOM   4425 C CA  . GLU B 1 109 ? -4.06900  -33.95000 -20.79700 1.000 29.99773  ? 109 GLU B CA  1 
ATOM   4426 C C   . GLU B 1 109 ? -3.48500  -32.63800 -20.30700 1.000 29.15145  ? 109 GLU B C   1 
ATOM   4427 O O   . GLU B 1 109 ? -3.70600  -32.24100 -19.15400 1.000 27.95621  ? 109 GLU B O   1 
ATOM   4428 C CB  . GLU B 1 109 ? -5.27700  -33.67900 -21.70500 1.000 29.04527  ? 109 GLU B CB  1 
ATOM   4429 C CG  . GLU B 1 109 ? -6.34100  -32.86700 -21.06200 1.000 27.10889  ? 109 GLU B CG  1 
ATOM   4430 C CD  . GLU B 1 109 ? -7.39600  -32.42400 -22.05300 1.000 31.06362  ? 109 GLU B CD  1 
ATOM   4431 O OE1 . GLU B 1 109 ? -7.03600  -31.95200 -23.14800 1.000 33.50890  ? 109 GLU B OE1 1 
ATOM   4432 O OE2 . GLU B 1 109 ? -8.58900  -32.55300 -21.73400 1.000 31.65674  ? 109 GLU B OE2 1 
ATOM   4433 N N   . PRO B 1 110 ? -2.70600  -31.95000 -21.14400 1.000 30.90603  ? 110 PRO B N   1 
ATOM   4434 C CA  . PRO B 1 110 ? -1.98700  -30.74700 -20.69300 1.000 29.54880  ? 110 PRO B CA  1 
ATOM   4435 C C   . PRO B 1 110 ? -2.90900  -29.69800 -20.07900 1.000 27.47017  ? 110 PRO B C   1 
ATOM   4436 O O   . PRO B 1 110 ? -3.93100  -29.32900 -20.65100 1.000 31.44720  ? 110 PRO B O   1 
ATOM   4437 C CB  . PRO B 1 110 ? -1.33000  -30.23500 -21.97700 1.000 29.45458  ? 110 PRO B CB  1 
ATOM   4438 C CG  . PRO B 1 110 ? -1.11800  -31.45700 -22.80500 1.000 33.86811  ? 110 PRO B CG  1 
ATOM   4439 C CD  . PRO B 1 110 ? -2.26400  -32.39100 -22.48500 1.000 34.56402  ? 110 PRO B CD  1 
ATOM   4440 N N   . ALA B 1 111 ? -2.54000  -29.21900 -18.89800 1.000 28.58245  ? 111 ALA B N   1 
ATOM   4441 C CA  . ALA B 1 111 ? -3.36000  -28.28300 -18.14200 1.000 33.40658  ? 111 ALA B CA  1 
ATOM   4442 C C   . ALA B 1 111 ? -3.28600  -26.88400 -18.74800 1.000 34.38707  ? 111 ALA B C   1 
ATOM   4443 O O   . ALA B 1 111 ? -2.41400  -26.57300 -19.56200 1.000 38.15939  ? 111 ALA B O   1 
ATOM   4444 C CB  . ALA B 1 111 ? -2.91300  -28.23500 -16.68000 1.000 35.73863  ? 111 ALA B CB  1 
ATOM   4445 N N   . GLU B 1 112 ? -4.21800  -26.03000 -18.33000 1.000 38.80908  ? 112 GLU B N   1 
ATOM   4446 C CA  . GLU B 1 112 ? -4.22400  -24.63900 -18.75900 1.000 38.10576  ? 112 GLU B CA  1 
ATOM   4447 C C   . GLU B 1 112 ? -3.03300  -23.91800 -18.15300 1.000 40.70171  ? 112 GLU B C   1 
ATOM   4448 O O   . GLU B 1 112 ? -2.79100  -24.01900 -16.94500 1.000 43.27817  ? 112 GLU B O   1 
ATOM   4449 C CB  . GLU B 1 112 ? -5.52300  -23.96300 -18.33200 1.000 36.65102  ? 112 GLU B CB  1 
ATOM   4450 C CG  . GLU B 1 112 ? -5.54500  -22.46900 -18.57200 1.000 38.99793  ? 112 GLU B CG  1 
ATOM   4451 C CD  . GLU B 1 112 ? -5.46500  -22.12100 -20.04800 1.000 41.26581  ? 112 GLU B CD  1 
ATOM   4452 O OE1 . GLU B 1 112 ? -6.40800  -22.47200 -20.82000 1.000 32.54999  ? 112 GLU B OE1 1 
ATOM   4453 O OE2 . GLU B 1 112 ? -4.44300  -21.50200 -20.42800 1.000 42.07720  ? 112 GLU B OE2 1 
ATOM   4454 N N   . LEU B 1 113 ? -2.27400  -23.20500 -18.99300 1.000 41.50035  ? 113 LEU B N   1 
ATOM   4455 C CA  . LEU B 1 113 ? -1.09300  -22.48900 -18.51700 1.000 47.58766  ? 113 LEU B CA  1 
ATOM   4456 C C   . LEU B 1 113 ? -1.30900  -20.98900 -18.35900 1.000 51.24829  ? 113 LEU B C   1 
ATOM   4457 O O   . LEU B 1 113 ? -0.55500  -20.34800 -17.62000 1.000 53.28425  ? 113 LEU B O   1 
ATOM   4458 C CB  . LEU B 1 113 ? 0.09600   -22.71400 -19.45500 1.000 40.38199  ? 113 LEU B CB  1 
ATOM   4459 C CG  . LEU B 1 113 ? 0.74700   -24.09900 -19.45800 1.000 48.46868  ? 113 LEU B CG  1 
ATOM   4460 C CD1 . LEU B 1 113 ? 1.92500   -24.11800 -20.42200 1.000 56.58272  ? 113 LEU B CD1 1 
ATOM   4461 C CD2 . LEU B 1 113 ? 1.18900   -24.53500 -18.06600 1.000 51.13818  ? 113 LEU B CD2 1 
ATOM   4462 N N   . GLN B 1 114 ? -2.31100  -20.41900 -19.02000 1.000 46.60258  ? 114 GLN B N   1 
ATOM   4463 C CA  . GLN B 1 114 ? -2.54500  -18.98700 -18.94000 1.000 49.91572  ? 114 GLN B CA  1 
ATOM   4464 C C   . GLN B 1 114 ? -3.19900  -18.65500 -17.59800 1.000 52.36188  ? 114 GLN B C   1 
ATOM   4465 O O   . GLN B 1 114 ? -4.38000  -18.97100 -17.38300 1.000 51.12956  ? 114 GLN B O   1 
ATOM   4466 C CB  . GLN B 1 114 ? -3.39900  -18.53300 -20.13000 1.000 45.69027  ? 114 GLN B CB  1 
ATOM   4467 C CG  . GLN B 1 114 ? -3.03600  -17.15400 -20.67200 1.000 65.53188  ? 114 GLN B CG  1 
ATOM   4468 C CD  . GLN B 1 114 ? -3.87500  -16.03900 -20.04900 1.000 70.47875  ? 114 GLN B CD  1 
ATOM   4469 O OE1 . GLN B 1 114 ? -5.11200  -16.03400 -20.16800 1.000 61.59514  ? 114 GLN B OE1 1 
ATOM   4470 N NE2 . GLN B 1 114 ? -3.20600  -15.09100 -19.37500 1.000 63.20766  ? 114 GLN B NE2 1 
ATOM   4471 N N   . PRO B 1 115 ? -2.47100  -18.00300 -16.67800 1.000 54.95448  ? 115 PRO B N   1 
ATOM   4472 C CA  . PRO B 1 115 ? -3.01000  -17.82000 -15.31500 1.000 51.49460  ? 115 PRO B CA  1 
ATOM   4473 C C   . PRO B 1 115 ? -4.30200  -17.02800 -15.28100 1.000 52.21176  ? 115 PRO B C   1 
ATOM   4474 O O   . PRO B 1 115 ? -5.18800  -17.34400 -14.47900 1.000 50.71418  ? 115 PRO B O   1 
ATOM   4475 C CB  . PRO B 1 115 ? -1.88500  -17.07300 -14.58300 1.000 51.12253  ? 115 PRO B CB  1 
ATOM   4476 C CG  . PRO B 1 115 ? -0.70100  -17.08600 -15.52500 1.000 54.22056  ? 115 PRO B CG  1 
ATOM   4477 C CD  . PRO B 1 115 ? -1.24800  -17.21500 -16.89700 1.000 57.05326  ? 115 PRO B CD  1 
ATOM   4478 N N   . GLY B 1 116 ? -4.44200  -16.01600 -16.13600 1.000 49.68745  ? 116 GLY B N   1 
ATOM   4479 C CA  . GLY B 1 116 ? -5.61600  -15.16300 -16.10100 1.000 54.61320  ? 116 GLY B CA  1 
ATOM   4480 C C   . GLY B 1 116 ? -6.75800  -15.59600 -17.00300 1.000 50.16792  ? 116 GLY B C   1 
ATOM   4481 O O   . GLY B 1 116 ? -7.57500  -14.76600 -17.42700 1.000 45.60053  ? 116 GLY B O   1 
ATOM   4482 N N   . MET B 1 117 ? -6.83300  -16.89700 -17.29700 1.000 45.06397  ? 117 MET B N   1 
ATOM   4483 C CA  . MET B 1 117 ? -7.85800  -17.38900 -18.21200 1.000 42.35186  ? 117 MET B CA  1 
ATOM   4484 C C   . MET B 1 117 ? -9.25600  -17.11800 -17.66900 1.000 38.90701  ? 117 MET B C   1 
ATOM   4485 O O   . MET B 1 117 ? -10.14000 -16.64800 -18.39700 1.000 37.87684  ? 117 MET B O   1 
ATOM   4486 C CB  . MET B 1 117 ? -7.66000  -18.88200 -18.47100 1.000 40.04948  ? 117 MET B CB  1 
ATOM   4487 C CG  . MET B 1 117 ? -8.60100  -19.46000 -19.53700 1.000 38.28912  ? 117 MET B CG  1 
ATOM   4488 S SD  . MET B 1 117 ? -10.22100 -19.99500 -18.92100 1.000 43.89561  ? 117 MET B SD  1 
ATOM   4489 C CE  . MET B 1 117 ? -9.76200  -21.38000 -17.85800 1.000 41.42607  ? 117 MET B CE  1 
ATOM   4490 N N   . GLU B 1 118 ? -9.48000  -17.43200 -16.39400 1.000 36.87935  ? 118 GLU B N   1 
ATOM   4491 C CA  . GLU B 1 118 ? -10.81900 -17.30500 -15.83400 1.000 38.27811  ? 118 GLU B CA  1 
ATOM   4492 C C   . GLU B 1 118 ? -11.23500 -15.84100 -15.70800 1.000 41.40719  ? 118 GLU B C   1 
ATOM   4493 O O   . GLU B 1 118 ? -12.42200 -15.51700 -15.83700 1.000 36.05957  ? 118 GLU B O   1 
ATOM   4494 C CB  . GLU B 1 118 ? -10.87700 -18.02100 -14.48600 1.000 38.21081  ? 118 GLU B CB  1 
ATOM   4495 C CG  . GLU B 1 118 ? -10.73000 -19.54200 -14.57000 1.000 42.75131  ? 118 GLU B CG  1 
ATOM   4496 C CD  . GLU B 1 118 ? -9.28100  -20.02900 -14.62100 1.000 47.39432  ? 118 GLU B CD  1 
ATOM   4497 O OE1 . GLU B 1 118 ? -8.34000  -19.20300 -14.59500 1.000 43.74102  ? 118 GLU B OE1 1 
ATOM   4498 O OE2 . GLU B 1 118 ? -9.08200  -21.26300 -14.68300 1.000 53.64759  ? 118 GLU B OE2 1 
ATOM   4499 N N   . GLU B 1 119 ? -10.27400 -14.94000 -15.48600 1.000 43.29430  ? 119 GLU B N   1 
ATOM   4500 C CA  . GLU B 1 119 ? -10.58500 -13.51300 -15.48200 1.000 43.00124  ? 119 GLU B CA  1 
ATOM   4501 C C   . GLU B 1 119 ? -11.09800 -13.06600 -16.84300 1.000 41.90029  ? 119 GLU B C   1 
ATOM   4502 O O   . GLU B 1 119 ? -12.11600 -12.37100 -16.94100 1.000 38.02434  ? 119 GLU B O   1 
ATOM   4503 C CB  . GLU B 1 119 ? -9.35600  -12.70700 -15.09100 1.000 42.99405  ? 119 GLU B CB  1 
ATOM   4504 C CG  . GLU B 1 119 ? -9.66700  -11.30300 -14.64300 1.000 48.24371  ? 119 GLU B CG  1 
ATOM   4505 C CD  . GLU B 1 119 ? -8.43400  -10.60700 -14.09600 1.000 59.09867  ? 119 GLU B CD  1 
ATOM   4506 O OE1 . GLU B 1 119 ? -7.33600  -10.88000 -14.63800 1.000 59.32295  ? 119 GLU B OE1 1 
ATOM   4507 O OE2 . GLU B 1 119 ? -8.55700  -9.81200  -13.12500 1.000 55.63967  ? 119 GLU B OE2 1 
ATOM   4508 N N   . THR B 1 120 ? -10.40200 -13.45400 -17.91100 1.000 40.40603  ? 120 THR B N   1 
ATOM   4509 C CA  . THR B 1 120 ? -10.89700 -13.13000 -19.24300 1.000 41.54141  ? 120 THR B CA  1 
ATOM   4510 C C   . THR B 1 120 ? -12.19200 -13.88000 -19.54700 1.000 43.84368  ? 120 THR B C   1 
ATOM   4511 O O   . THR B 1 120 ? -13.07200 -13.34900 -20.23700 1.000 45.06943  ? 120 THR B O   1 
ATOM   4512 C CB  . THR B 1 120 ? -9.83400  -13.44600 -20.29400 1.000 40.21344  ? 120 THR B CB  1 
ATOM   4513 O OG1 . THR B 1 120 ? -8.54500  -13.05800 -19.81000 1.000 50.17923  ? 120 THR B OG1 1 
ATOM   4514 C CG2 . THR B 1 120 ? -10.10800 -12.67200 -21.54300 1.000 48.36275  ? 120 THR B CG2 1 
ATOM   4515 N N   . ALA B 1 121 ? -12.32500 -15.11200 -19.05000 1.000 44.95494  ? 121 ALA B N   1 
ATOM   4516 C CA  . ALA B 1 121 ? -13.58100 -15.83100 -19.19900 1.000 38.99901  ? 121 ALA B CA  1 
ATOM   4517 C C   . ALA B 1 121 ? -14.72600 -15.04800 -18.56400 1.000 44.55263  ? 121 ALA B C   1 
ATOM   4518 O O   . ALA B 1 121 ? -15.79300 -14.88400 -19.16600 1.000 44.11782  ? 121 ALA B O   1 
ATOM   4519 C CB  . ALA B 1 121 ? -13.45700 -17.22100 -18.57800 1.000 38.15404  ? 121 ALA B CB  1 
ATOM   4520 N N   . LEU B 1 122 ? -14.51300 -14.52600 -17.36000 1.000 42.55626  ? 122 LEU B N   1 
ATOM   4521 C CA  . LEU B 1 122 ? -15.57800 -13.78700 -16.69400 1.000 41.98528  ? 122 LEU B CA  1 
ATOM   4522 C C   . LEU B 1 122 ? -15.94200 -12.51300 -17.45600 1.000 43.62073  ? 122 LEU B C   1 
ATOM   4523 O O   . LEU B 1 122 ? -17.10700 -12.09200 -17.44500 1.000 40.92108  ? 122 LEU B O   1 
ATOM   4524 C CB  . LEU B 1 122 ? -15.15600 -13.47700 -15.25800 1.000 40.70047  ? 122 LEU B CB  1 
ATOM   4525 C CG  . LEU B 1 122 ? -16.23600 -13.21200 -14.22000 1.000 38.35011  ? 122 LEU B CG  1 
ATOM   4526 C CD1 . LEU B 1 122 ? -17.31500 -14.27100 -14.29900 1.000 39.60479  ? 122 LEU B CD1 1 
ATOM   4527 C CD2 . LEU B 1 122 ? -15.57900 -13.22400 -12.86300 1.000 46.66834  ? 122 LEU B CD2 1 
ATOM   4528 N N   . GLU B 1 123 ? -14.97900 -11.91200 -18.15900 1.000 42.25343  ? 123 GLU B N   1 
ATOM   4529 C CA  . GLU B 1 123 ? -15.26600 -10.68100 -18.89000 1.000 44.16925  ? 123 GLU B CA  1 
ATOM   4530 C C   . GLU B 1 123 ? -16.16900 -10.93300 -20.09400 1.000 48.11338  ? 123 GLU B C   1 
ATOM   4531 O O   . GLU B 1 123 ? -17.12700 -10.18300 -20.32400 1.000 52.42144  ? 123 GLU B O   1 
ATOM   4532 C CB  . GLU B 1 123 ? -13.96500 -10.00000 -19.32400 1.000 47.70307  ? 123 GLU B CB  1 
ATOM   4533 C CG  . GLU B 1 123 ? -13.38600 -9.08000  -18.25300 1.000 55.27589  ? 123 GLU B CG  1 
ATOM   4534 C CD  . GLU B 1 123 ? -14.45400 -8.19200  -17.61200 1.000 60.88078  ? 123 GLU B CD  1 
ATOM   4535 O OE1 . GLU B 1 123 ? -15.04200 -7.34800  -18.33300 1.000 54.67906  ? 123 GLU B OE1 1 
ATOM   4536 O OE2 . GLU B 1 123 ? -14.71800 -8.35800  -16.39400 1.000 59.20183  ? 123 GLU B OE2 1 
ATOM   4537 N N   . VAL B 1 124 ? -15.86400 -11.95800 -20.90000 1.000 48.90428  ? 124 VAL B N   1 
ATOM   4538 C CA  . VAL B 1 124 ? -16.74100 -12.26700 -22.03000 1.000 41.33532  ? 124 VAL B CA  1 
ATOM   4539 C C   . VAL B 1 124 ? -18.11700 -12.70600 -21.53400 1.000 43.11273  ? 124 VAL B C   1 
ATOM   4540 O O   . VAL B 1 124 ? -19.13200 -12.40500 -22.17400 1.000 48.78418  ? 124 VAL B O   1 
ATOM   4541 C CB  . VAL B 1 124 ? -16.12000 -13.32600 -22.97500 1.000 43.67946  ? 124 VAL B CB  1 
ATOM   4542 C CG1 . VAL B 1 124 ? -15.02300 -12.73600 -23.80700 1.000 40.45905  ? 124 VAL B CG1 1 
ATOM   4543 C CG2 . VAL B 1 124 ? -15.58200 -14.51800 -22.21100 1.000 43.90871  ? 124 VAL B CG2 1 
ATOM   4544 N N   . VAL B 1 125 ? -18.18200 -13.41100 -20.39700 1.000 36.15864  ? 125 VAL B N   1 
ATOM   4545 C CA  . VAL B 1 125 ? -19.47500 -13.77800 -19.81800 1.000 45.80994  ? 125 VAL B CA  1 
ATOM   4546 C C   . VAL B 1 125 ? -20.32600 -12.53600 -19.57400 1.000 50.30636  ? 125 VAL B C   1 
ATOM   4547 O O   . VAL B 1 125 ? -21.53300 -12.52500 -19.86100 1.000 47.20533  ? 125 VAL B O   1 
ATOM   4548 C CB  . VAL B 1 125 ? -19.26800 -14.59300 -18.52700 1.000 39.82055  ? 125 VAL B CB  1 
ATOM   4549 C CG1 . VAL B 1 125 ? -20.40900 -14.35500 -17.53500 1.000 34.70700  ? 125 VAL B CG1 1 
ATOM   4550 C CG2 . VAL B 1 125 ? -19.17200 -16.05500 -18.87400 1.000 38.00180  ? 125 VAL B CG2 1 
ATOM   4551 N N   . ARG B 1 126 ? -19.70300 -11.46800 -19.05700 1.000 44.58176  ? 126 ARG B N   1 
ATOM   4552 C CA  . ARG B 1 126 ? -20.38700 -10.19200 -18.87400 1.000 49.16782  ? 126 ARG B CA  1 
ATOM   4553 C C   . ARG B 1 126 ? -20.95000 -9.67100  -20.19200 1.000 52.99685  ? 126 ARG B C   1 
ATOM   4554 O O   . ARG B 1 126 ? -22.05200 -9.10500  -20.23100 1.000 48.23347  ? 126 ARG B O   1 
ATOM   4555 C CB  . ARG B 1 126 ? -19.41500 -9.17400  -18.26800 1.000 48.35580  ? 126 ARG B CB  1 
ATOM   4556 C CG  . ARG B 1 126 ? -20.05300 -8.17100  -17.31600 1.000 55.62688  ? 126 ARG B CG  1 
ATOM   4557 C CD  . ARG B 1 126 ? -19.01600 -7.24600  -16.68700 1.000 58.87025  ? 126 ARG B CD  1 
ATOM   4558 N NE  . ARG B 1 126 ? -17.91400 -7.99100  -16.08700 1.000 59.67487  ? 126 ARG B NE  1 
ATOM   4559 C CZ  . ARG B 1 126 ? -17.93200 -8.49400  -14.85900 1.000 60.48884  ? 126 ARG B CZ  1 
ATOM   4560 N NH1 . ARG B 1 126 ? -18.99300 -8.36000  -14.07000 1.000 55.59878  ? 126 ARG B NH1 1 
ATOM   4561 N NH2 . ARG B 1 126 ? -16.86000 -9.15000  -14.41200 1.000 50.94140  ? 126 ARG B NH2 1 
ATOM   4562 N N   . ARG B 1 127 ? -20.20100 -9.85000  -21.28200 1.000 49.26459  ? 127 ARG B N   1 
ATOM   4563 C CA  . ARG B 1 127 ? -20.63300 -9.37300  -22.58800 1.000 52.08341  ? 127 ARG B CA  1 
ATOM   4564 C C   . ARG B 1 127 ? -21.86200 -10.11600 -23.10500 1.000 55.46603  ? 127 ARG B C   1 
ATOM   4565 O O   . ARG B 1 127 ? -22.62100 -9.56100  -23.90800 1.000 58.71645  ? 127 ARG B O   1 
ATOM   4566 C CB  . ARG B 1 127 ? -19.46800 -9.49900  -23.56700 1.000 55.24051  ? 127 ARG B CB  1 
ATOM   4567 C CG  . ARG B 1 127 ? -19.66500 -8.79100  -24.88000 1.000 64.75796  ? 127 ARG B CG  1 
ATOM   4568 C CD  . ARG B 1 127 ? -18.42200 -8.90300  -25.76600 1.000 74.53975  ? 127 ARG B CD  1 
ATOM   4569 N NE  . ARG B 1 127 ? -18.20300 -7.66800  -26.51500 1.000 88.32825  ? 127 ARG B NE  1 
ATOM   4570 C CZ  . ARG B 1 127 ? -17.38000 -7.53800  -27.54800 1.000 87.62868  ? 127 ARG B CZ  1 
ATOM   4571 N NH1 . ARG B 1 127 ? -16.69000 -8.56700  -28.01800 1.000 83.50802  ? 127 ARG B NH1 1 
ATOM   4572 N NH2 . ARG B 1 127 ? -17.25000 -6.34600  -28.12800 1.000 79.87056  ? 127 ARG B NH2 1 
ATOM   4573 N N   . LEU B 1 128 ? -22.09300 -11.34400 -22.65100 1.000 53.15945  ? 128 LEU B N   1 
ATOM   4574 C CA  . LEU B 1 128 ? -23.21600 -12.14200 -23.12300 1.000 54.72534  ? 128 LEU B CA  1 
ATOM   4575 C C   . LEU B 1 128 ? -24.41800 -12.10300 -22.18400 1.000 58.46317  ? 128 LEU B C   1 
ATOM   4576 O O   . LEU B 1 128 ? -25.40300 -12.81000 -22.42000 1.000 62.21233  ? 128 LEU B O   1 
ATOM   4577 C CB  . LEU B 1 128 ? -22.76700 -13.59200 -23.34500 1.000 46.97853  ? 128 LEU B CB  1 
ATOM   4578 C CG  . LEU B 1 128 ? -23.52500 -14.35700 -24.42400 1.000 45.34363  ? 128 LEU B CG  1 
ATOM   4579 C CD1 . LEU B 1 128 ? -23.83900 -13.46900 -25.62100 1.000 43.25363  ? 128 LEU B CD1 1 
ATOM   4580 C CD2 . LEU B 1 128 ? -22.71300 -15.54800 -24.83700 1.000 40.85696  ? 128 LEU B CD2 1 
ATOM   4581 N N   . VAL B 1 129 ? -24.37200 -11.30700 -21.12800 1.000 58.02817  ? 129 VAL B N   1 
ATOM   4582 C CA  . VAL B 1 129 ? -25.58200 -11.09300 -20.34900 1.000 61.60725  ? 129 VAL B CA  1 
ATOM   4583 C C   . VAL B 1 129 ? -26.04200 -9.66400  -20.62700 1.000 69.74361  ? 129 VAL B C   1 
ATOM   4584 O O   . VAL B 1 129 ? -27.12000 -9.44900  -21.20200 1.000 70.68053  ? 129 VAL B O   1 
ATOM   4585 C CB  . VAL B 1 129 ? -25.35400 -11.38400 -18.85100 1.000 61.07125  ? 129 VAL B CB  1 
ATOM   4586 C CG1 . VAL B 1 129 ? -25.32700 -12.88000 -18.61900 1.000 58.36580  ? 129 VAL B CG1 1 
ATOM   4587 C CG2 . VAL B 1 129 ? -24.03100 -10.79200 -18.36500 1.000 61.13028  ? 129 VAL B CG2 1 
ATOM   4588 N N   . SER B 1 130 ? -25.20200 -8.67800  -20.26500 1.000 69.61897  ? 130 SER B N   1 
ATOM   4589 C CA  . SER B 1 130 ? -25.44200 -7.25900  -20.49900 1.000 73.23920  ? 130 SER B CA  1 
ATOM   4590 C C   . SER B 1 130 ? -26.79800 -6.85500  -19.92600 1.000 86.43531  ? 130 SER B C   1 
ATOM   4591 O O   . SER B 1 130 ? -27.44500 -7.65600  -19.23600 1.000 82.24420  ? 130 SER B O   1 
ATOM   4592 C CB  . SER B 1 130 ? -25.36500 -6.94600  -21.99900 1.000 77.91675  ? 130 SER B CB  1 
ATOM   4593 O OG  . SER B 1 130 ? -26.59800 -7.23900  -22.64300 1.000 86.63618  ? 130 SER B OG  1 
ATOM   4594 N N   . PRO B 1 131 ? -27.25100 -5.61700  -20.13900 1.000 95.41789  ? 131 PRO B N   1 
ATOM   4595 C CA  . PRO B 1 131 ? -28.68500 -5.35000  -19.97500 1.000 94.43059  ? 131 PRO B CA  1 
ATOM   4596 C C   . PRO B 1 131 ? -29.53300 -6.26900  -20.85400 1.000 91.00306  ? 131 PRO B C   1 
ATOM   4597 O O   . PRO B 1 131 ? -29.94900 -7.34500  -20.40500 1.000 83.59423  ? 131 PRO B O   1 
ATOM   4598 C CB  . PRO B 1 131 ? -28.80600 -3.87300  -20.37500 1.000 97.72598  ? 131 PRO B CB  1 
ATOM   4599 C CG  . PRO B 1 131 ? -27.49700 -3.28300  -19.92500 1.000 88.78880  ? 131 PRO B CG  1 
ATOM   4600 C CD  . PRO B 1 131 ? -26.46100 -4.36500  -20.15300 1.000 90.40077  ? 131 PRO B CD  1 
ATOM   4601 N N   . LEU B 1 132 ? -29.78700 -5.87300  -22.10400 1.000 93.09094  ? 132 LEU B N   1 
ATOM   4602 C CA  . LEU B 1 132 ? -30.62600 -6.63300  -23.02200 1.000 89.40635  ? 132 LEU B CA  1 
ATOM   4603 C C   . LEU B 1 132 ? -29.82300 -7.01500  -24.25600 1.000 92.14494  ? 132 LEU B C   1 
ATOM   4604 O O   . LEU B 1 132 ? -29.03000 -6.21700  -24.77200 1.000 89.45812  ? 132 LEU B O   1 
ATOM   4605 C CB  . LEU B 1 132 ? -31.88400 -5.84400  -23.44300 1.000 87.85433  ? 132 LEU B CB  1 
ATOM   4606 C CG  . LEU B 1 132 ? -32.77000 -6.37800  -24.58400 1.000 85.29124  ? 132 LEU B CG  1 
ATOM   4607 C CD1 . LEU B 1 132 ? -33.67000 -7.54500  -24.16500 1.000 72.31101  ? 132 LEU B CD1 1 
ATOM   4608 C CD2 . LEU B 1 132 ? -33.60400 -5.24300  -25.16500 1.000 86.07014  ? 132 LEU B CD2 1 
ATOM   4609 N N   . ALA B 1 133 ? -30.02900 -8.24700  -24.70900 1.000 91.23807  ? 133 ALA B N   1 
ATOM   4610 C CA  . ALA B 1 133 ? -29.43600 -8.77300  -25.92600 1.000 90.95181  ? 133 ALA B CA  1 
ATOM   4611 C C   . ALA B 1 133 ? -30.52400 -8.97600  -26.97500 1.000 84.57171  ? 133 ALA B C   1 
ATOM   4612 O O   . ALA B 1 133 ? -31.72300 -8.82300  -26.71200 1.000 78.62206  ? 133 ALA B O   1 
ATOM   4613 C CB  . ALA B 1 133 ? -28.68400 -10.08300 -25.65000 1.000 80.26886  ? 133 ALA B CB  1 
ATOM   4614 N N   . GLY B 1 134 ? -30.08400 -9.33100  -28.18000 1.000 81.73696  ? 134 GLY B N   1 
ATOM   4615 C CA  . GLY B 1 134 ? -30.97800 -9.33600  -29.31400 1.000 69.86323  ? 134 GLY B CA  1 
ATOM   4616 C C   . GLY B 1 134 ? -31.48300 -7.96400  -29.67900 1.000 75.25097  ? 134 GLY B C   1 
ATOM   4617 O O   . GLY B 1 134 ? -32.45300 -7.86000  -30.43100 1.000 77.58436  ? 134 GLY B O   1 
ATOM   4618 N N   . VAL B 1 135 ? -30.82100 -6.90600  -29.18800 1.000 76.11642  ? 135 VAL B N   1 
ATOM   4619 C CA  . VAL B 1 135 ? -31.38900 -5.55600  -29.22200 1.000 78.37452  ? 135 VAL B CA  1 
ATOM   4620 C C   . VAL B 1 135 ? -31.70200 -5.11800  -30.65200 1.000 81.36213  ? 135 VAL B C   1 
ATOM   4621 O O   . VAL B 1 135 ? -32.70100 -4.42100  -30.89500 1.000 79.61231  ? 135 VAL B O   1 
ATOM   4622 C CB  . VAL B 1 135 ? -30.45000 -4.56600  -28.50600 1.000 78.75861  ? 135 VAL B CB  1 
ATOM   4623 C CG1 . VAL B 1 135 ? -30.58200 -4.73100  -27.01000 1.000 75.84040  ? 135 VAL B CG1 1 
ATOM   4624 C CG2 . VAL B 1 135 ? -28.99100 -4.77200  -28.95200 1.000 77.67787  ? 135 VAL B CG2 1 
ATOM   4625 N N   . LYS B 1 136 ? -30.86200 -5.50300  -31.61400 1.000 82.33399  ? 136 LYS B N   1 
ATOM   4626 C CA  . LYS B 1 136 ? -31.21100 -5.44000  -33.03700 1.000 82.12458  ? 136 LYS B CA  1 
ATOM   4627 C C   . LYS B 1 136 ? -31.25600 -6.87100  -33.56600 1.000 74.85322  ? 136 LYS B C   1 
ATOM   4628 O O   . LYS B 1 136 ? -30.39800 -7.30600  -34.34300 1.000 71.53431  ? 136 LYS B O   1 
ATOM   4629 C CB  . LYS B 1 136 ? -30.23900 -4.55900  -33.85500 1.000 76.31608  ? 136 LYS B CB  1 
ATOM   4630 C CG  . LYS B 1 136 ? -30.66600 -3.08800  -34.02500 1.000 73.42989  ? 136 LYS B CG  1 
ATOM   4631 C CD  . LYS B 1 136 ? -32.15800 -2.90900  -34.33500 1.000 64.13787  ? 136 LYS B CD  1 
ATOM   4632 C CE  . LYS B 1 136 ? -32.43600 -1.65900  -35.16100 1.000 64.52818  ? 136 LYS B CE  1 
ATOM   4633 N NZ  . LYS B 1 136 ? -31.26500 -0.78700  -35.40200 1.000 56.66168  ? 136 LYS B NZ  1 
ATOM   4634 N N   . GLY B 1 137 ? -32.26900 -7.60800  -33.12300 1.000 74.07264  ? 137 GLY B N   1 
ATOM   4635 C CA  . GLY B 1 137 ? -32.45800 -8.97600  -33.54500 1.000 69.71710  ? 137 GLY B CA  1 
ATOM   4636 C C   . GLY B 1 137 ? -31.63000 -9.97400  -32.76100 1.000 72.40537  ? 137 GLY B C   1 
ATOM   4637 O O   . GLY B 1 137 ? -30.51700 -9.66700  -32.31400 1.000 74.63939  ? 137 GLY B O   1 
ATOM   4638 N N   . THR B 1 138 ? -32.16300 -11.19000 -32.61200 1.000 70.05404  ? 138 THR B N   1 
ATOM   4639 C CA  . THR B 1 138 ? -31.41900 -12.32400 -32.08000 1.000 62.25182  ? 138 THR B CA  1 
ATOM   4640 C C   . THR B 1 138 ? -30.23700 -12.63500 -32.99700 1.000 54.38072  ? 138 THR B C   1 
ATOM   4641 O O   . THR B 1 138 ? -29.39500 -13.47900 -32.69400 1.000 54.45036  ? 138 THR B O   1 
ATOM   4642 C CB  . THR B 1 138 ? -32.34400 -13.53500 -31.94100 1.000 61.89961  ? 138 THR B CB  1 
ATOM   4643 O OG1 . THR B 1 138 ? -32.82300 -13.91200 -33.23400 1.000 55.25100  ? 138 THR B OG1 1 
ATOM   4644 C CG2 . THR B 1 138 ? -33.53900 -13.19000 -31.05000 1.000 60.96136  ? 138 THR B CG2 1 
ATOM   4645 N N   . GLN B 1 139 ? -30.19000 -11.96400 -34.14200 1.000 61.06646  ? 139 GLN B N   1 
ATOM   4646 C CA  . GLN B 1 139 ? -29.02100 -12.02600 -35.00600 1.000 60.49271  ? 139 GLN B CA  1 
ATOM   4647 C C   . GLN B 1 139 ? -27.78900 -11.47300 -34.30400 1.000 57.46488  ? 139 GLN B C   1 
ATOM   4648 O O   . GLN B 1 139 ? -26.73400 -12.11600 -34.26900 1.000 56.24878  ? 139 GLN B O   1 
ATOM   4649 C CB  . GLN B 1 139 ? -29.29400 -11.24700 -36.28700 1.000 64.37300  ? 139 GLN B CB  1 
ATOM   4650 C CG  . GLN B 1 139 ? -28.16800 -11.32400 -37.27600 1.000 63.84664  ? 139 GLN B CG  1 
ATOM   4651 C CD  . GLN B 1 139 ? -27.80300 -12.75300 -37.60400 1.000 64.92405  ? 139 GLN B CD  1 
ATOM   4652 O OE1 . GLN B 1 139 ? -28.67400 -13.61300 -37.75200 1.000 62.57540  ? 139 GLN B OE1 1 
ATOM   4653 N NE2 . GLN B 1 139 ? -26.50500 -13.01900 -37.71200 1.000 61.26825  ? 139 GLN B NE2 1 
ATOM   4654 N N   . ALA B 1 140 ? -27.89200 -10.26400 -33.76100 1.000 54.32680  ? 140 ALA B N   1 
ATOM   4655 C CA  . ALA B 1 140 ? -26.76800 -9.75100  -32.99400 1.000 55.94522  ? 140 ALA B CA  1 
ATOM   4656 C C   . ALA B 1 140 ? -26.45800 -10.63300 -31.79400 1.000 48.85299  ? 140 ALA B C   1 
ATOM   4657 O O   . ALA B 1 140 ? -25.34200 -10.57900 -31.27200 1.000 39.42925  ? 140 ALA B O   1 
ATOM   4658 C CB  . ALA B 1 140 ? -27.03600 -8.31400  -32.54400 1.000 58.72008  ? 140 ALA B CB  1 
ATOM   4659 N N   . LEU B 1 141 ? -27.41000 -11.45800 -31.35500 1.000 49.94873  ? 141 LEU B N   1 
ATOM   4660 C CA  . LEU B 1 141 ? -27.12400 -12.36300 -30.24800 1.000 49.50585  ? 141 LEU B CA  1 
ATOM   4661 C C   . LEU B 1 141 ? -26.11200 -13.42600 -30.66000 1.000 47.96749  ? 141 LEU B C   1 
ATOM   4662 O O   . LEU B 1 141 ? -25.08900 -13.61400 -29.98700 1.000 46.17063  ? 141 LEU B O   1 
ATOM   4663 C CB  . LEU B 1 141 ? -28.41600 -13.00300 -29.74800 1.000 53.77914  ? 141 LEU B CB  1 
ATOM   4664 C CG  . LEU B 1 141 ? -28.43100 -13.50900 -28.31300 1.000 53.89642  ? 141 LEU B CG  1 
ATOM   4665 C CD1 . LEU B 1 141 ? -27.19200 -13.06000 -27.54500 1.000 47.03520  ? 141 LEU B CD1 1 
ATOM   4666 C CD2 . LEU B 1 141 ? -29.70200 -13.01300 -27.64100 1.000 55.51302  ? 141 LEU B CD2 1 
ATOM   4667 N N   . LEU B 1 142 ? -26.37800 -14.12500 -31.77200 1.000 46.93334  ? 142 LEU B N   1 
ATOM   4668 C CA  . LEU B 1 142 ? -25.46300 -15.16000 -32.24800 1.000 38.98526  ? 142 LEU B CA  1 
ATOM   4669 C C   . LEU B 1 142 ? -24.09500 -14.58300 -32.58100 1.000 41.59372  ? 142 LEU B C   1 
ATOM   4670 O O   . LEU B 1 142 ? -23.06000 -15.19900 -32.29600 1.000 44.30358  ? 142 LEU B O   1 
ATOM   4671 C CB  . LEU B 1 142 ? -26.04000 -15.85000 -33.47700 1.000 43.83821  ? 142 LEU B CB  1 
ATOM   4672 C CG  . LEU B 1 142 ? -27.17100 -16.87000 -33.29900 1.000 41.38972  ? 142 LEU B CG  1 
ATOM   4673 C CD1 . LEU B 1 142 ? -27.51500 -17.08000 -31.84900 1.000 40.04747  ? 142 LEU B CD1 1 
ATOM   4674 C CD2 . LEU B 1 142 ? -28.40400 -16.46000 -34.08200 1.000 44.71372  ? 142 LEU B CD2 1 
ATOM   4675 N N   . GLN B 1 143 ? -24.07000 -13.40100 -33.19000 1.000 42.75627  ? 143 GLN B N   1 
ATOM   4676 C CA  . GLN B 1 143 ? -22.79900 -12.81500 -33.59700 1.000 45.97397  ? 143 GLN B CA  1 
ATOM   4677 C C   . GLN B 1 143 ? -21.91400 -12.50400 -32.39200 1.000 41.80411  ? 143 GLN B C   1 
ATOM   4678 O O   . GLN B 1 143 ? -20.68400 -12.59600 -32.47900 1.000 37.52107  ? 143 GLN B O   1 
ATOM   4679 C CB  . GLN B 1 143 ? -23.05800 -11.56200 -34.42700 1.000 38.52270  ? 143 GLN B CB  1 
ATOM   4680 C CG  . GLN B 1 143 ? -21.79200 -10.87600 -34.85000 1.000 42.39764  ? 143 GLN B CG  1 
ATOM   4681 C CD  . GLN B 1 143 ? -20.96400 -11.73600 -35.76900 1.000 39.44561  ? 143 GLN B CD  1 
ATOM   4682 O OE1 . GLN B 1 143 ? -21.49300 -12.37400 -36.68200 1.000 39.17422  ? 143 GLN B OE1 1 
ATOM   4683 N NE2 . GLN B 1 143 ? -19.65400 -11.76400 -35.53500 1.000 41.21535  ? 143 GLN B NE2 1 
ATOM   4684 N N   . THR B 1 144 ? -22.52400 -12.15100 -31.26200 1.000 40.82484  ? 144 THR B N   1 
ATOM   4685 C CA  . THR B 1 144 ? -21.76900 -11.96100 -30.03200 1.000 41.49882  ? 144 THR B CA  1 
ATOM   4686 C C   . THR B 1 144 ? -21.20800 -13.29100 -29.53600 1.000 42.88711  ? 144 THR B C   1 
ATOM   4687 O O   . THR B 1 144 ? -19.99900 -13.41200 -29.28500 1.000 46.09622  ? 144 THR B O   1 
ATOM   4688 C CB  . THR B 1 144 ? -22.66500 -11.30300 -28.97700 1.000 45.59113  ? 144 THR B CB  1 
ATOM   4689 O OG1 . THR B 1 144 ? -23.38600 -10.22500 -29.58100 1.000 40.59957  ? 144 THR B OG1 1 
ATOM   4690 C CG2 . THR B 1 144 ? -21.84400 -10.76000 -27.81800 1.000 39.23469  ? 144 THR B CG2 1 
ATOM   4691 N N   . ALA B 1 145 ? -22.07000 -14.30700 -29.40700 1.000 40.99065  ? 145 ALA B N   1 
ATOM   4692 C CA  . ALA B 1 145 ? -21.62100 -15.64700 -29.03600 1.000 39.45333  ? 145 ALA B CA  1 
ATOM   4693 C C   . ALA B 1 145 ? -20.48400 -16.12400 -29.93800 1.000 40.94861  ? 145 ALA B C   1 
ATOM   4694 O O   . ALA B 1 145 ? -19.45700 -16.60900 -29.45300 1.000 42.46175  ? 145 ALA B O   1 
ATOM   4695 C CB  . ALA B 1 145 ? -22.79400 -16.62600 -29.08700 1.000 37.80238  ? 145 ALA B CB  1 
ATOM   4696 N N   . ALA B 1 146 ? -20.64000 -15.98600 -31.26000 1.000 41.52843  ? 146 ALA B N   1 
ATOM   4697 C CA  . ALA B 1 146 ? -19.54500 -16.34400 -32.16100 1.000 36.75569  ? 146 ALA B CA  1 
ATOM   4698 C C   . ALA B 1 146 ? -18.27200 -15.57700 -31.81400 1.000 40.18404  ? 146 ALA B C   1 
ATOM   4699 O O   . ALA B 1 146 ? -17.19600 -16.17100 -31.68200 1.000 40.58593  ? 146 ALA B O   1 
ATOM   4700 C CB  . ALA B 1 146 ? -19.94500 -16.09200 -33.61300 1.000 37.63147  ? 146 ALA B CB  1 
ATOM   4701 N N   . ASP B 1 147 ? -18.38100 -14.25100 -31.64500 1.000 44.12222  ? 147 ASP B N   1 
ATOM   4702 C CA  . ASP B 1 147 ? -17.20700 -13.41600 -31.37500 1.000 40.58170  ? 147 ASP B CA  1 
ATOM   4703 C C   . ASP B 1 147 ? -16.55200 -13.73900 -30.03700 1.000 41.21363  ? 147 ASP B C   1 
ATOM   4704 O O   . ASP B 1 147 ? -15.33800 -13.53300 -29.87200 1.000 39.21009  ? 147 ASP B O   1 
ATOM   4705 C CB  . ASP B 1 147 ? -17.58700 -11.93800 -31.37300 1.000 40.48694  ? 147 ASP B CB  1 
ATOM   4706 C CG  . ASP B 1 147 ? -17.76600 -11.36800 -32.76000 1.000 47.48494  ? 147 ASP B CG  1 
ATOM   4707 O OD1 . ASP B 1 147 ? -17.18100 -11.91400 -33.72100 1.000 51.17762  ? 147 ASP B OD1 1 
ATOM   4708 O OD2 . ASP B 1 147 ? -18.48400 -10.35100 -32.87900 1.000 47.12100  ? 147 ASP B OD2 1 
ATOM   4709 N N   . THR B 1 148 ? -17.34000 -14.17900 -29.05200 1.000 41.44641  ? 148 THR B N   1 
ATOM   4710 C CA  . THR B 1 148 ? -16.80000 -14.40200 -27.71100 1.000 41.40815  ? 148 THR B CA  1 
ATOM   4711 C C   . THR B 1 148 ? -16.13600 -15.76900 -27.60000 1.000 42.39764  ? 148 THR B C   1 
ATOM   4712 O O   . THR B 1 148 ? -15.08200 -15.90700 -26.96800 1.000 39.18709  ? 148 THR B O   1 
ATOM   4713 C CB  . THR B 1 148 ? -17.90500 -14.25900 -26.65600 1.000 46.42270  ? 148 THR B CB  1 
ATOM   4714 O OG1 . THR B 1 148 ? -18.98400 -15.15700 -26.95600 1.000 44.17258  ? 148 THR B OG1 1 
ATOM   4715 C CG2 . THR B 1 148 ? -18.44100 -12.82200 -26.61400 1.000 46.78137  ? 148 THR B CG2 1 
ATOM   4716 N N   . VAL B 1 149 ? -16.73100 -16.79500 -28.20000 1.000 35.32473  ? 149 VAL B N   1 
ATOM   4717 C CA  . VAL B 1 149 ? -16.02200 -18.05900 -28.28200 1.000 36.46748  ? 149 VAL B CA  1 
ATOM   4718 C C   . VAL B 1 149 ? -14.69500 -17.86400 -29.00800 1.000 43.28171  ? 149 VAL B C   1 
ATOM   4719 O O   . VAL B 1 149 ? -13.65800 -18.38400 -28.58000 1.000 41.22236  ? 149 VAL B O   1 
ATOM   4720 C CB  . VAL B 1 149 ? -16.90900 -19.12100 -28.95900 1.000 40.31658  ? 149 VAL B CB  1 
ATOM   4721 C CG1 . VAL B 1 149 ? -16.13100 -20.41900 -29.15100 1.000 39.99279  ? 149 VAL B CG1 1 
ATOM   4722 C CG2 . VAL B 1 149 ? -18.15800 -19.36600 -28.12200 1.000 35.32233  ? 149 VAL B CG2 1 
ATOM   4723 N N   . ARG B 1 150 ? -14.69100 -17.07100 -30.08900 1.000 38.91134  ? 150 ARG B N   1 
ATOM   4724 C CA  . ARG B 1 150 ? -13.44900 -16.86700 -30.82800 1.000 36.39094  ? 150 ARG B CA  1 
ATOM   4725 C C   . ARG B 1 150 ? -12.45100 -16.04300 -30.02500 1.000 39.96370  ? 150 ARG B C   1 
ATOM   4726 O O   . ARG B 1 150 ? -11.23900 -16.27800 -30.10800 1.000 42.20841  ? 150 ARG B O   1 
ATOM   4727 C CB  . ARG B 1 150 ? -13.71500 -16.19800 -32.17100 1.000 36.31693  ? 150 ARG B CB  1 
ATOM   4728 C CG  . ARG B 1 150 ? -12.50800 -16.26600 -33.07400 1.000 41.58235  ? 150 ARG B CG  1 
ATOM   4729 C CD  . ARG B 1 150 ? -12.80900 -15.82300 -34.49000 1.000 42.17256  ? 150 ARG B CD  1 
ATOM   4730 N NE  . ARG B 1 150 ? -12.17200 -14.54100 -34.76400 1.000 54.30376  ? 150 ARG B NE  1 
ATOM   4731 C CZ  . ARG B 1 150 ? -10.86000 -14.38400 -34.89700 1.000 57.58531  ? 150 ARG B CZ  1 
ATOM   4732 N NH1 . ARG B 1 150 ? -10.02400 -15.41300 -34.79900 1.000 53.57351  ? 150 ARG B NH1 1 
ATOM   4733 N NH2 . ARG B 1 150 ? -10.37000 -13.16500 -35.12000 1.000 53.26425  ? 150 ARG B NH2 1 
ATOM   4734 N N   . ALA B 1 151 ? -12.93800 -15.06200 -29.25700 1.000 40.38725  ? 151 ALA B N   1 
ATOM   4735 C CA  . ALA B 1 151 ? -12.05500 -14.29700 -28.38100 1.000 38.41897  ? 151 ALA B CA  1 
ATOM   4736 C C   . ALA B 1 151 ? -11.43900 -15.19200 -27.32300 1.000 41.86928  ? 151 ALA B C   1 
ATOM   4737 O O   . ALA B 1 151 ? -10.24300 -15.09500 -27.03300 1.000 41.35326  ? 151 ALA B O   1 
ATOM   4738 C CB  . ALA B 1 151 ? -12.82100 -13.15800 -27.71800 1.000 31.12326  ? 151 ALA B CB  1 
ATOM   4739 N N   . LEU B 1 152 ? -12.24300 -16.09800 -26.76200 1.000 42.99175  ? 152 LEU B N   1 
ATOM   4740 C CA  . LEU B 1 152 ? -11.80400 -16.94600 -25.66500 1.000 41.02451  ? 152 LEU B CA  1 
ATOM   4741 C C   . LEU B 1 152 ? -10.90100 -18.08800 -26.12900 1.000 42.84172  ? 152 LEU B C   1 
ATOM   4742 O O   . LEU B 1 152 ? -9.98800  -18.48300 -25.39400 1.000 45.40964  ? 152 LEU B O   1 
ATOM   4743 C CB  . LEU B 1 152 ? -13.02900 -17.49800 -24.92400 1.000 34.84867  ? 152 LEU B CB  1 
ATOM   4744 C CG  . LEU B 1 152 ? -12.69000 -18.24500 -23.63700 1.000 36.88248  ? 152 LEU B CG  1 
ATOM   4745 C CD1 . LEU B 1 152 ? -11.72200 -17.41200 -22.80800 1.000 37.17191  ? 152 LEU B CD1 1 
ATOM   4746 C CD2 . LEU B 1 152 ? -13.93000 -18.58400 -22.83800 1.000 33.86695  ? 152 LEU B CD2 1 
ATOM   4747 N N   . THR B 1 153 ? -11.13400 -18.63400 -27.32300 1.000 43.54837  ? 153 THR B N   1 
ATOM   4748 C CA  . THR B 1 153 ? -10.41400 -19.81800 -27.78700 1.000 38.81852  ? 153 THR B CA  1 
ATOM   4749 C C   . THR B 1 153 ? -9.20500  -19.49700 -28.64800 1.000 36.99965  ? 153 THR B C   1 
ATOM   4750 O O   . THR B 1 153 ? -8.22400  -20.23900 -28.60400 1.000 41.52657  ? 153 THR B O   1 
ATOM   4751 C CB  . THR B 1 153 ? -11.33500 -20.73100 -28.60800 1.000 40.54985  ? 153 THR B CB  1 
ATOM   4752 O OG1 . THR B 1 153 ? -11.79700 -20.02300 -29.76600 1.000 44.50407  ? 153 THR B OG1 1 
ATOM   4753 C CG2 . THR B 1 153 ? -12.52800 -21.18500 -27.79800 1.000 34.59393  ? 153 THR B CG2 1 
ATOM   4754 N N   . GLY B 1 154 ? -9.26400  -18.43500 -29.45200 1.000 41.17273  ? 154 GLY B N   1 
ATOM   4755 C CA  . GLY B 1 154 ? -8.24300  -18.16500 -30.44300 1.000 37.74958  ? 154 GLY B CA  1 
ATOM   4756 C C   . GLY B 1 154 ? -8.39700  -18.90500 -31.75300 1.000 36.68033  ? 154 GLY B C   1 
ATOM   4757 O O   . GLY B 1 154 ? -7.45600  -18.91100 -32.55400 1.000 37.70396  ? 154 GLY B O   1 
ATOM   4758 N N   . PHE B 1 155 ? -9.55200  -19.51500 -32.01100 1.000 40.47962  ? 155 PHE B N   1 
ATOM   4759 C CA  . PHE B 1 155 ? -9.72600  -20.31800 -33.21400 1.000 39.40518  ? 155 PHE B CA  1 
ATOM   4760 C C   . PHE B 1 155 ? -9.87400  -19.42100 -34.43300 1.000 44.04539  ? 155 PHE B C   1 
ATOM   4761 O O   . PHE B 1 155 ? -10.49800 -18.35700 -34.37200 1.000 45.35673  ? 155 PHE B O   1 
ATOM   4762 C CB  . PHE B 1 155 ? -10.94400 -21.24000 -33.08000 1.000 39.77252  ? 155 PHE B CB  1 
ATOM   4763 C CG  . PHE B 1 155 ? -10.58900 -22.67000 -32.74200 1.000 37.92501  ? 155 PHE B CG  1 
ATOM   4764 C CD1 . PHE B 1 155 ? -9.93500  -22.97100 -31.56500 1.000 38.13465  ? 155 PHE B CD1 1 
ATOM   4765 C CD2 . PHE B 1 155 ? -10.90800 -23.70500 -33.60500 1.000 37.23107  ? 155 PHE B CD2 1 
ATOM   4766 C CE1 . PHE B 1 155 ? -9.59800  -24.27700 -31.24400 1.000 39.77676  ? 155 PHE B CE1 1 
ATOM   4767 C CE2 . PHE B 1 155 ? -10.58600 -25.01800 -33.28900 1.000 40.56108  ? 155 PHE B CE2 1 
ATOM   4768 C CZ  . PHE B 1 155 ? -9.91300  -25.30200 -32.09900 1.000 35.96990  ? 155 PHE B CZ  1 
ATOM   4769 N N   . ASP B 1 156 ? -9.28600  -19.85400 -35.54800 1.000 41.45829  ? 156 ASP B N   1 
ATOM   4770 C CA  . ASP B 1 156 ? -9.32000  -19.03100 -36.74400 1.000 40.13760  ? 156 ASP B CA  1 
ATOM   4771 C C   . ASP B 1 156 ? -10.74000 -18.80200 -37.23000 1.000 45.95676  ? 156 ASP B C   1 
ATOM   4772 O O   . ASP B 1 156 ? -10.99900 -17.78800 -37.88200 1.000 48.34564  ? 156 ASP B O   1 
ATOM   4773 C CB  . ASP B 1 156 ? -8.47300  -19.66400 -37.84800 1.000 40.64828  ? 156 ASP B CB  1 
ATOM   4774 C CG  . ASP B 1 156 ? -6.98000  -19.65400 -37.51300 1.000 46.34645  ? 156 ASP B CG  1 
ATOM   4775 O OD1 . ASP B 1 156 ? -6.53400  -18.71200 -36.82600 1.000 47.22480  ? 156 ASP B OD1 1 
ATOM   4776 O OD2 . ASP B 1 156 ? -6.25100  -20.58800 -37.92400 1.000 48.05979  ? 156 ASP B OD2 1 
ATOM   4777 N N   . ARG B 1 157 ? -11.67800 -19.68800 -36.91400 1.000 42.78302  ? 157 ARG B N   1 
ATOM   4778 C CA  . ARG B 1 157 ? -13.03900 -19.45000 -37.36700 1.000 33.55641  ? 157 ARG B CA  1 
ATOM   4779 C C   . ARG B 1 157 ? -14.01700 -20.10900 -36.41900 1.000 36.72837  ? 157 ARG B C   1 
ATOM   4780 O O   . ARG B 1 157 ? -13.77300 -21.21100 -35.91800 1.000 36.54618  ? 157 ARG B O   1 
ATOM   4781 C CB  . ARG B 1 157 ? -13.23900 -19.96900 -38.78200 1.000 33.86928  ? 157 ARG B CB  1 
ATOM   4782 C CG  . ARG B 1 157 ? -14.67000 -19.96100 -39.27900 1.000 38.33352  ? 157 ARG B CG  1 
ATOM   4783 C CD  . ARG B 1 157 ? -14.69900 -20.38500 -40.73100 1.000 35.88635  ? 157 ARG B CD  1 
ATOM   4784 N NE  . ARG B 1 157 ? -14.15500 -21.72500 -40.91400 1.000 39.52299  ? 157 ARG B NE  1 
ATOM   4785 C CZ  . ARG B 1 157 ? -13.44800 -22.10700 -41.96900 1.000 38.54195  ? 157 ARG B CZ  1 
ATOM   4786 N NH1 . ARG B 1 157 ? -13.08500 -21.24900 -42.90200 1.000 41.96298  ? 157 ARG B NH1 1 
ATOM   4787 N NH2 . ARG B 1 157 ? -13.10400 -23.38500 -42.09700 1.000 38.16591  ? 157 ARG B NH2 1 
ATOM   4788 N N   . VAL B 1 158 ? -15.12500 -19.42200 -36.18400 1.000 33.91523  ? 158 VAL B N   1 
ATOM   4789 C CA  . VAL B 1 158 ? -16.15700 -19.86300 -35.25600 1.000 35.14198  ? 158 VAL B CA  1 
ATOM   4790 C C   . VAL B 1 158 ? -17.49800 -19.59000 -35.91500 1.000 35.12409  ? 158 VAL B C   1 
ATOM   4791 O O   . VAL B 1 158 ? -17.72500 -18.49200 -36.43400 1.000 35.47492  ? 158 VAL B O   1 
ATOM   4792 C CB  . VAL B 1 158 ? -16.05100 -19.13400 -33.90200 1.000 32.52241  ? 158 VAL B CB  1 
ATOM   4793 C CG1 . VAL B 1 158 ? -17.21100 -19.48400 -33.02500 1.000 34.94665  ? 158 VAL B CG1 1 
ATOM   4794 C CG2 . VAL B 1 158 ? -14.72600 -19.46700 -33.21400 1.000 34.41829  ? 158 VAL B CG2 1 
ATOM   4795 N N   . MET B 1 159 ? -18.37500 -20.58400 -35.91900 1.000 34.23900  ? 159 MET B N   1 
ATOM   4796 C CA  . MET B 1 159 ? -19.63400 -20.49100 -36.64500 1.000 33.59243  ? 159 MET B CA  1 
ATOM   4797 C C   . MET B 1 159 ? -20.77700 -21.03400 -35.78700 1.000 31.83145  ? 159 MET B C   1 
ATOM   4798 O O   . MET B 1 159 ? -20.61100 -22.01500 -35.05000 1.000 29.35744  ? 159 MET B O   1 
ATOM   4799 C CB  . MET B 1 159 ? -19.54100 -21.25800 -37.96700 1.000 32.43899  ? 159 MET B CB  1 
ATOM   4800 C CG  . MET B 1 159 ? -18.36500 -20.87200 -38.82600 1.000 35.19079  ? 159 MET B CG  1 
ATOM   4801 S SD  . MET B 1 159 ? -17.91400 -22.28300 -39.89100 1.000 37.23001  ? 159 MET B SD  1 
ATOM   4802 C CE  . MET B 1 159 ? -17.20600 -23.42800 -38.70400 1.000 35.30634  ? 159 MET B CE  1 
ATOM   4803 N N   . VAL B 1 160 ? -21.93200 -20.38700 -35.86900 1.000 29.63225  ? 160 VAL B N   1 
ATOM   4804 C CA  . VAL B 1 160 ? -23.12400 -20.82000 -35.14300 1.000 30.76795  ? 160 VAL B CA  1 
ATOM   4805 C C   . VAL B 1 160 ? -23.98600 -21.59600 -36.12400 1.000 30.33812  ? 160 VAL B C   1 
ATOM   4806 O O   . VAL B 1 160 ? -24.48400 -21.03700 -37.10900 1.000 29.11873  ? 160 VAL B O   1 
ATOM   4807 C CB  . VAL B 1 160 ? -23.89600 -19.64000 -34.54500 1.000 31.77350  ? 160 VAL B CB  1 
ATOM   4808 C CG1 . VAL B 1 160 ? -25.25900 -20.12100 -34.03600 1.000 26.46504  ? 160 VAL B CG1 1 
ATOM   4809 C CG2 . VAL B 1 160 ? -23.07400 -18.98000 -33.43500 1.000 31.32400  ? 160 VAL B CG2 1 
ATOM   4810 N N   . TYR B 1 161 ? -24.14600 -22.88400 -35.86800 1.000 27.14628  ? 161 TYR B N   1 
ATOM   4811 C CA  . TYR B 1 161 ? -24.74500 -23.81400 -36.80700 1.000 27.24916  ? 161 TYR B CA  1 
ATOM   4812 C C   . TYR B 1 161 ? -26.05600 -24.31400 -36.21000 1.000 32.11590  ? 161 TYR B C   1 
ATOM   4813 O O   . TYR B 1 161 ? -26.07300 -24.80700 -35.07700 1.000 31.90441  ? 161 TYR B O   1 
ATOM   4814 C CB  . TYR B 1 161 ? -23.77400 -24.95900 -37.08000 1.000 24.33326  ? 161 TYR B CB  1 
ATOM   4815 C CG  . TYR B 1 161 ? -24.17300 -25.99000 -38.12200 1.000 31.41355  ? 161 TYR B CG  1 
ATOM   4816 C CD1 . TYR B 1 161 ? -23.95700 -25.76300 -39.47300 1.000 32.02512  ? 161 TYR B CD1 1 
ATOM   4817 C CD2 . TYR B 1 161 ? -24.71100 -27.22100 -37.74400 1.000 30.88793  ? 161 TYR B CD2 1 
ATOM   4818 C CE1 . TYR B 1 161 ? -24.29000 -26.71600 -40.42300 1.000 32.53333  ? 161 TYR B CE1 1 
ATOM   4819 C CE2 . TYR B 1 161 ? -25.04800 -28.18200 -38.69400 1.000 33.03074  ? 161 TYR B CE2 1 
ATOM   4820 C CZ  . TYR B 1 161 ? -24.83000 -27.92200 -40.03300 1.000 32.80639  ? 161 TYR B CZ  1 
ATOM   4821 O OH  . TYR B 1 161 ? -25.16500 -28.86900 -40.99200 1.000 38.43867  ? 161 TYR B OH  1 
ATOM   4822 N N   . ARG B 1 162 ? -27.15400 -24.16500 -36.95800 1.000 31.32488  ? 162 ARG B N   1 
ATOM   4823 C CA  . ARG B 1 162 ? -28.48400 -24.53100 -36.48400 1.000 31.81655  ? 162 ARG B CA  1 
ATOM   4824 C C   . ARG B 1 162 ? -29.02400 -25.70600 -37.27800 1.000 31.10185  ? 162 ARG B C   1 
ATOM   4825 O O   . ARG B 1 162 ? -28.80400 -25.80300 -38.48700 1.000 32.76253  ? 162 ARG B O   1 
ATOM   4826 C CB  . ARG B 1 162 ? -29.45700 -23.36200 -36.60100 1.000 40.89317  ? 162 ARG B CB  1 
ATOM   4827 C CG  . ARG B 1 162 ? -30.86500 -23.66200 -36.09300 1.000 39.00794  ? 162 ARG B CG  1 
ATOM   4828 C CD  . ARG B 1 162 ? -31.76100 -22.45400 -36.31000 1.000 41.20566  ? 162 ARG B CD  1 
ATOM   4829 N NE  . ARG B 1 162 ? -32.01500 -22.23000 -37.72700 1.000 46.03360  ? 162 ARG B NE  1 
ATOM   4830 C CZ  . ARG B 1 162 ? -32.71500 -21.21700 -38.22400 1.000 55.54580  ? 162 ARG B CZ  1 
ATOM   4831 N NH1 . ARG B 1 162 ? -33.19000 -20.25200 -37.44800 1.000 54.90526  ? 162 ARG B NH1 1 
ATOM   4832 N NH2 . ARG B 1 162 ? -32.94600 -21.16900 -39.53500 1.000 54.38732  ? 162 ARG B NH2 1 
ATOM   4833 N N   . PHE B 1 163 ? -29.73900 -26.59100 -36.59700 1.000 32.41038  ? 163 PHE B N   1 
ATOM   4834 C CA  . PHE B 1 163 ? -30.34100 -27.73400 -37.25700 1.000 38.69214  ? 163 PHE B CA  1 
ATOM   4835 C C   . PHE B 1 163 ? -31.70300 -27.36700 -37.81800 1.000 41.74694  ? 163 PHE B C   1 
ATOM   4836 O O   . PHE B 1 163 ? -32.50800 -26.70800 -37.15400 1.000 43.81594  ? 163 PHE B O   1 
ATOM   4837 C CB  . PHE B 1 163 ? -30.47700 -28.91000 -36.28900 1.000 35.63733  ? 163 PHE B CB  1 
ATOM   4838 C CG  . PHE B 1 163 ? -29.19000 -29.62400 -36.04100 1.000 38.42151  ? 163 PHE B CG  1 
ATOM   4839 C CD1 . PHE B 1 163 ? -28.59300 -30.36900 -37.04600 1.000 36.16538  ? 163 PHE B CD1 1 
ATOM   4840 C CD2 . PHE B 1 163 ? -28.55900 -29.52900 -34.82000 1.000 34.07117  ? 163 PHE B CD2 1 
ATOM   4841 C CE1 . PHE B 1 163 ? -27.40600 -31.01000 -36.82900 1.000 36.19815  ? 163 PHE B CE1 1 
ATOM   4842 C CE2 . PHE B 1 163 ? -27.36800 -30.18500 -34.59500 1.000 29.79047  ? 163 PHE B CE2 1 
ATOM   4843 C CZ  . PHE B 1 163 ? -26.79100 -30.91900 -35.59000 1.000 33.33466  ? 163 PHE B CZ  1 
ATOM   4844 N N   . ASP B 1 164 ? -31.96100 -27.79900 -39.04500 1.000 36.99969  ? 164 ASP B N   1 
ATOM   4845 C CA  . ASP B 1 164 ? -33.32800 -27.74600 -39.52600 1.000 42.79339  ? 164 ASP B CA  1 
ATOM   4846 C C   . ASP B 1 164 ? -34.11700 -28.93100 -38.98300 1.000 41.75162  ? 164 ASP B C   1 
ATOM   4847 O O   . ASP B 1 164 ? -33.58300 -29.80400 -38.29000 1.000 41.64195  ? 164 ASP B O   1 
ATOM   4848 C CB  . ASP B 1 164 ? -33.37700 -27.73100 -41.04200 1.000 43.94038  ? 164 ASP B CB  1 
ATOM   4849 C CG  . ASP B 1 164 ? -34.57400 -26.97500 -41.55600 1.000 57.02499  ? 164 ASP B CG  1 
ATOM   4850 O OD1 . ASP B 1 164 ? -35.63900 -27.02700 -40.89400 1.000 56.58867  ? 164 ASP B OD1 1 
ATOM   4851 O OD2 . ASP B 1 164 ? -34.43500 -26.29800 -42.60000 1.000 67.01515  ? 164 ASP B OD2 1 
ATOM   4852 N N   . ALA B 1 165 ? -35.41100 -28.97100 -39.31700 1.000 44.30121  ? 165 ALA B N   1 
ATOM   4853 C CA  . ALA B 1 165 ? -36.26900 -30.03200 -38.79700 1.000 48.57752  ? 165 ALA B CA  1 
ATOM   4854 C C   . ALA B 1 165 ? -35.89600 -31.38600 -39.37600 1.000 44.27052  ? 165 ALA B C   1 
ATOM   4855 O O   . ALA B 1 165 ? -36.10000 -32.41300 -38.71800 1.000 46.26896  ? 165 ALA B O   1 
ATOM   4856 C CB  . ALA B 1 165 ? -37.74000 -29.72300 -39.07600 1.000 45.68019  ? 165 ALA B CB  1 
ATOM   4857 N N   . ASP B 1 166 ? -35.35400 -31.40900 -40.59300 1.000 39.52740  ? 166 ASP B N   1 
ATOM   4858 C CA  . ASP B 1 166 ? -34.83400 -32.62400 -41.19600 1.000 42.27105  ? 166 ASP B CA  1 
ATOM   4859 C C   . ASP B 1 166 ? -33.34800 -32.84200 -40.89000 1.000 45.18438  ? 166 ASP B C   1 
ATOM   4860 O O   . ASP B 1 166 ? -32.68300 -33.61600 -41.59100 1.000 47.38957  ? 166 ASP B O   1 
ATOM   4861 C CB  . ASP B 1 166 ? -35.07400 -32.59800 -42.70700 1.000 46.43596  ? 166 ASP B CB  1 
ATOM   4862 C CG  . ASP B 1 166 ? -34.44300 -31.38300 -43.38700 1.000 50.18670  ? 166 ASP B CG  1 
ATOM   4863 O OD1 . ASP B 1 166 ? -33.80700 -30.55400 -42.69500 1.000 45.57855  ? 166 ASP B OD1 1 
ATOM   4864 O OD2 . ASP B 1 166 ? -34.59100 -31.26400 -44.62600 1.000 57.56721  ? 166 ASP B OD2 1 
ATOM   4865 N N   . TRP B 1 167 ? -32.81300 -32.16000 -39.88100 1.000 42.08438  ? 167 TRP B N   1 
ATOM   4866 C CA  . TRP B 1 167 ? -31.44600 -32.33700 -39.39600 1.000 39.28712  ? 167 TRP B CA  1 
ATOM   4867 C C   . TRP B 1 167 ? -30.38900 -31.93900 -40.41500 1.000 38.26104  ? 167 TRP B C   1 
ATOM   4868 O O   . TRP B 1 167 ? -29.19700 -32.17800 -40.19000 1.000 38.09807  ? 167 TRP B O   1 
ATOM   4869 C CB  . TRP B 1 167 ? -31.21300 -33.77000 -38.89400 1.000 36.67733  ? 167 TRP B CB  1 
ATOM   4870 C CG  . TRP B 1 167 ? -32.09800 -34.02100 -37.71900 1.000 40.82811  ? 167 TRP B CG  1 
ATOM   4871 C CD1 . TRP B 1 167 ? -33.27900 -34.70500 -37.71000 1.000 39.75603  ? 167 TRP B CD1 1 
ATOM   4872 C CD2 . TRP B 1 167 ? -31.92400 -33.50500 -36.39400 1.000 39.91565  ? 167 TRP B CD2 1 
ATOM   4873 N NE1 . TRP B 1 167 ? -33.83500 -34.67300 -36.45400 1.000 37.54441  ? 167 TRP B NE1 1 
ATOM   4874 C CE2 . TRP B 1 167 ? -33.02600 -33.94000 -35.62800 1.000 42.28655  ? 167 TRP B CE2 1 
ATOM   4875 C CE3 . TRP B 1 167 ? -30.93900 -32.72300 -35.78000 1.000 38.74936  ? 167 TRP B CE3 1 
ATOM   4876 C CZ2 . TRP B 1 167 ? -33.17000 -33.62700 -34.27500 1.000 44.48855  ? 167 TRP B CZ2 1 
ATOM   4877 C CZ3 . TRP B 1 167 ? -31.08500 -32.40700 -34.43800 1.000 46.07630  ? 167 TRP B CZ3 1 
ATOM   4878 C CH2 . TRP B 1 167 ? -32.19600 -32.85600 -33.70000 1.000 43.09990  ? 167 TRP B CH2 1 
ATOM   4879 N N   . HIS B 1 168 ? -30.76900 -31.28900 -41.50800 1.000 39.95686  ? 168 HIS B N   1 
ATOM   4880 C CA  . HIS B 1 168 ? -29.73400 -30.54500 -42.20200 1.000 37.41770  ? 168 HIS B CA  1 
ATOM   4881 C C   . HIS B 1 168 ? -29.53800 -29.19800 -41.49800 1.000 33.39953  ? 168 HIS B C   1 
ATOM   4882 O O   . HIS B 1 168 ? -30.30500 -28.81500 -40.60900 1.000 29.84535  ? 168 HIS B O   1 
ATOM   4883 C CB  . HIS B 1 168 ? -30.07200 -30.42900 -43.69400 1.000 39.17315  ? 168 HIS B CB  1 
ATOM   4884 C CG  . HIS B 1 168 ? -30.68200 -29.12500 -44.10300 1.000 39.90748  ? 168 HIS B CG  1 
ATOM   4885 N ND1 . HIS B 1 168 ? -32.03600 -28.87400 -44.02300 1.000 42.58022  ? 168 HIS B ND1 1 
ATOM   4886 C CD2 . HIS B 1 168 ? -30.12700 -28.01700 -44.65100 1.000 41.29060  ? 168 HIS B CD2 1 
ATOM   4887 C CE1 . HIS B 1 168 ? -32.28300 -27.65500 -44.47600 1.000 43.00778  ? 168 HIS B CE1 1 
ATOM   4888 N NE2 . HIS B 1 168 ? -31.14100 -27.11400 -44.86300 1.000 41.55456  ? 168 HIS B NE2 1 
ATOM   4889 N N   . GLY B 1 169 ? -28.45800 -28.49700 -41.83900 1.000 34.94764  ? 169 GLY B N   1 
ATOM   4890 C CA  . GLY B 1 169 ? -28.06000 -27.32900 -41.08500 1.000 36.42932  ? 169 GLY B CA  1 
ATOM   4891 C C   . GLY B 1 169 ? -27.75300 -26.13300 -41.96600 1.000 36.94006  ? 169 GLY B C   1 
ATOM   4892 O O   . GLY B 1 169 ? -27.55400 -26.25300 -43.17600 1.000 39.78920  ? 169 GLY B O   1 
ATOM   4893 N N   . GLU B 1 170 ? -27.73000 -24.95800 -41.33200 1.000 32.17159  ? 170 GLU B N   1 
ATOM   4894 C CA  . GLU B 1 170 ? -27.15500 -23.77300 -41.95000 1.000 38.48865  ? 170 GLU B CA  1 
ATOM   4895 C C   . GLU B 1 170 ? -26.31700 -23.00700 -40.94200 1.000 39.94257  ? 170 GLU B C   1 
ATOM   4896 O O   . GLU B 1 170 ? -26.65500 -22.93600 -39.75600 1.000 40.58550  ? 170 GLU B O   1 
ATOM   4897 C CB  . GLU B 1 170 ? -28.21400 -22.83300 -42.54300 1.000 43.20960  ? 170 GLU B CB  1 
ATOM   4898 C CG  . GLU B 1 170 ? -29.35800 -22.46000 -41.62100 1.000 43.48286  ? 170 GLU B CG  1 
ATOM   4899 C CD  . GLU B 1 170 ? -30.31200 -21.46600 -42.27900 1.000 50.44540  ? 170 GLU B CD  1 
ATOM   4900 O OE1 . GLU B 1 170 ? -29.85200 -20.63800 -43.10500 1.000 46.18956  ? 170 GLU B OE1 1 
ATOM   4901 O OE2 . GLU B 1 170 ? -31.52400 -21.51800 -41.97500 1.000 59.11251  ? 170 GLU B OE2 1 
ATOM   4902 N N   . VAL B 1 171 ? -25.21700 -22.44300 -41.42400 1.000 39.58362  ? 171 VAL B N   1 
ATOM   4903 C CA  . VAL B 1 171 ? -24.42900 -21.51500 -40.62700 1.000 36.78453  ? 171 VAL B CA  1 
ATOM   4904 C C   . VAL B 1 171 ? -25.18200 -20.19500 -40.57100 1.000 37.16361  ? 171 VAL B C   1 
ATOM   4905 O O   . VAL B 1 171 ? -25.40100 -19.55400 -41.60300 1.000 40.04679  ? 171 VAL B O   1 
ATOM   4906 C CB  . VAL B 1 171 ? -23.02400 -21.33800 -41.21600 1.000 36.70060  ? 171 VAL B CB  1 
ATOM   4907 C CG1 . VAL B 1 171 ? -22.26100 -20.22500 -40.48400 1.000 35.51276  ? 171 VAL B CG1 1 
ATOM   4908 C CG2 . VAL B 1 171 ? -22.28500 -22.63200 -41.11100 1.000 29.57300  ? 171 VAL B CG2 1 
ATOM   4909 N N   . LEU B 1 172 ? -25.58800 -19.79500 -39.36600 1.000 32.83771  ? 172 LEU B N   1 
ATOM   4910 C CA  . LEU B 1 172 ? -26.34500 -18.56800 -39.15300 1.000 32.93939  ? 172 LEU B CA  1 
ATOM   4911 C C   . LEU B 1 172 ? -25.46100 -17.38500 -38.81200 1.000 35.42218  ? 172 LEU B C   1 
ATOM   4912 O O   . LEU B 1 172 ? -25.82600 -16.24200 -39.10200 1.000 40.37097  ? 172 LEU B O   1 
ATOM   4913 C CB  . LEU B 1 172 ? -27.36700 -18.75500 -38.02200 1.000 35.47400  ? 172 LEU B CB  1 
ATOM   4914 C CG  . LEU B 1 172 ? -28.51200 -19.72900 -38.27800 1.000 43.58807  ? 172 LEU B CG  1 
ATOM   4915 C CD1 . LEU B 1 172 ? -29.49700 -19.68600 -37.12500 1.000 45.31058  ? 172 LEU B CD1 1 
ATOM   4916 C CD2 . LEU B 1 172 ? -29.19100 -19.38300 -39.59600 1.000 38.14847  ? 172 LEU B CD2 1 
ATOM   4917 N N   . ALA B 1 173 ? -24.30700 -17.63000 -38.20700 1.000 38.89600  ? 173 ALA B N   1 
ATOM   4918 C CA  . ALA B 1 173 ? -23.43000 -16.55600 -37.78200 1.000 35.51227  ? 173 ALA B CA  1 
ATOM   4919 C C   . ALA B 1 173 ? -22.00100 -17.06700 -37.82800 1.000 34.37975  ? 173 ALA B C   1 
ATOM   4920 O O   . ALA B 1 173 ? -21.74700 -18.27500 -37.82700 1.000 34.71178  ? 173 ALA B O   1 
ATOM   4921 C CB  . ALA B 1 173 ? -23.79700 -16.05800 -36.38100 1.000 37.05084  ? 173 ALA B CB  1 
ATOM   4922 N N   . GLU B 1 174 ? -21.06200 -16.13400 -37.86500 1.000 35.17919  ? 174 GLU B N   1 
ATOM   4923 C CA  . GLU B 1 174 ? -19.69300 -16.51400 -38.16400 1.000 33.65772  ? 174 GLU B CA  1 
ATOM   4924 C C   . GLU B 1 174 ? -18.74900 -15.43700 -37.66600 1.000 37.24047  ? 174 GLU B C   1 
ATOM   4925 O O   . GLU B 1 174 ? -19.01300 -14.24200 -37.84400 1.000 34.25055  ? 174 GLU B O   1 
ATOM   4926 C CB  . GLU B 1 174 ? -19.52200 -16.72300 -39.66000 1.000 34.06121  ? 174 GLU B CB  1 
ATOM   4927 C CG  . GLU B 1 174 ? -18.34500 -17.56000 -39.97900 1.000 40.91681  ? 174 GLU B CG  1 
ATOM   4928 C CD  . GLU B 1 174 ? -18.27000 -17.85800 -41.42800 1.000 45.77274  ? 174 GLU B CD  1 
ATOM   4929 O OE1 . GLU B 1 174 ? -18.50000 -16.92300 -42.22500 1.000 48.51974  ? 174 GLU B OE1 1 
ATOM   4930 O OE2 . GLU B 1 174 ? -17.99600 -19.02900 -41.77200 1.000 51.18972  ? 174 GLU B OE2 1 
ATOM   4931 N N   . SER B 1 175 ? -17.66400 -15.86300 -37.03200 1.000 38.70358  ? 175 SER B N   1 
ATOM   4932 C CA  . SER B 1 175 ? -16.63200 -14.95300 -36.55800 1.000 35.92313  ? 175 SER B CA  1 
ATOM   4933 C C   . SER B 1 175 ? -15.29900 -15.61300 -36.84900 1.000 40.21779  ? 175 SER B C   1 
ATOM   4934 O O   . SER B 1 175 ? -15.07900 -16.76200 -36.44600 1.000 38.09077  ? 175 SER B O   1 
ATOM   4935 C CB  . SER B 1 175 ? -16.80100 -14.65100 -35.07300 1.000 33.56092  ? 175 SER B CB  1 
ATOM   4936 O OG  . SER B 1 175 ? -15.69100 -13.95300 -34.55300 1.000 39.63201  ? 175 SER B OG  1 
ATOM   4937 N N   . LYS B 1 176 ? -14.44000 -14.90900 -37.58600 1.000 39.33522  ? 176 LYS B N   1 
ATOM   4938 C CA  . LYS B 1 176 ? -13.25700 -15.52900 -38.16300 1.000 46.38560  ? 176 LYS B CA  1 
ATOM   4939 C C   . LYS B 1 176 ? -12.22800 -14.44900 -38.47000 1.000 51.26712  ? 176 LYS B C   1 
ATOM   4940 O O   . LYS B 1 176 ? -12.56900 -13.27100 -38.60400 1.000 51.41806  ? 176 LYS B O   1 
ATOM   4941 C CB  . LYS B 1 176 ? -13.60000 -16.29000 -39.44400 1.000 43.72750  ? 176 LYS B CB  1 
ATOM   4942 C CG  . LYS B 1 176 ? -13.68000 -15.34500 -40.62100 1.000 49.56037  ? 176 LYS B CG  1 
ATOM   4943 C CD  . LYS B 1 176 ? -14.21200 -15.93400 -41.92100 1.000 55.33397  ? 176 LYS B CD  1 
ATOM   4944 C CE  . LYS B 1 176 ? -14.23000 -14.81300 -42.96800 1.000 58.35518  ? 176 LYS B CE  1 
ATOM   4945 N NZ  . LYS B 1 176 ? -14.96800 -15.14400 -44.22400 1.000 61.61317  ? 176 LYS B NZ  1 
ATOM   4946 N N   . ARG B 1 177 ? -10.96800 -14.87500 -38.60900 1.000 49.66557  ? 177 ARG B N   1 
ATOM   4947 C CA  . ARG B 1 177 ? -9.88500  -13.98000 -38.99600 1.000 51.52641  ? 177 ARG B CA  1 
ATOM   4948 C C   . ARG B 1 177 ? -10.09800 -13.40200 -40.38500 1.000 55.57125  ? 177 ARG B C   1 
ATOM   4949 O O   . ARG B 1 177 ? -10.69300 -14.03400 -41.26600 1.000 55.65351  ? 177 ARG B O   1 
ATOM   4950 C CB  . ARG B 1 177 ? -8.55200  -14.71300 -39.00500 1.000 54.15636  ? 177 ARG B CB  1 
ATOM   4951 C CG  . ARG B 1 177 ? -8.13100  -15.22200 -37.67600 1.000 58.44756  ? 177 ARG B CG  1 
ATOM   4952 C CD  . ARG B 1 177 ? -6.77000  -15.83900 -37.79900 1.000 63.92135  ? 177 ARG B CD  1 
ATOM   4953 N NE  . ARG B 1 177 ? -6.67000  -16.69700 -38.97600 1.000 63.30767  ? 177 ARG B NE  1 
ATOM   4954 C CZ  . ARG B 1 177 ? -5.88800  -16.44700 -40.01700 1.000 64.63445  ? 177 ARG B CZ  1 
ATOM   4955 N NH1 . ARG B 1 177 ? -5.14900  -15.34900 -40.07800 1.000 71.93499  ? 177 ARG B NH1 1 
ATOM   4956 N NH2 . ARG B 1 177 ? -5.83200  -17.32600 -41.01400 1.000 65.54477  ? 177 ARG B NH2 1 
ATOM   4957 N N   . GLY B 1 178 ? -9.55400  -12.20500 -40.58900 1.000 54.68168  ? 178 GLY B N   1 
ATOM   4958 C CA  . GLY B 1 178 ? -9.50300  -11.64800 -41.92800 1.000 53.40800  ? 178 GLY B CA  1 
ATOM   4959 C C   . GLY B 1 178 ? -8.81900  -12.59300 -42.89700 1.000 56.10792  ? 178 GLY B C   1 
ATOM   4960 O O   . GLY B 1 178 ? -7.91500  -13.35800 -42.53500 1.000 57.22067  ? 178 GLY B O   1 
ATOM   4961 N N   . GLY B 1 179 ? -9.27900  -12.56100 -44.14300 1.000 56.79368  ? 179 GLY B N   1 
ATOM   4962 C CA  . GLY B 1 179 ? -8.69400  -13.40500 -45.16000 1.000 59.93544  ? 179 GLY B CA  1 
ATOM   4963 C C   . GLY B 1 179 ? -8.99800  -14.87700 -45.02200 1.000 62.38338  ? 179 GLY B C   1 
ATOM   4964 O O   . GLY B 1 179 ? -8.48400  -15.67600 -45.81400 1.000 68.02393  ? 179 GLY B O   1 
ATOM   4965 N N   . MET B 1 180 ? -9.79100  -15.26700 -44.03200 1.000 60.39076  ? 180 MET B N   1 
ATOM   4966 C CA  . MET B 1 180 ? -10.30200 -16.62300 -43.96400 1.000 55.96836  ? 180 MET B CA  1 
ATOM   4967 C C   . MET B 1 180 ? -11.45500 -16.78600 -44.93900 1.000 54.86859  ? 180 MET B C   1 
ATOM   4968 O O   . MET B 1 180 ? -12.29500 -15.89200 -45.07900 1.000 42.92299  ? 180 MET B O   1 
ATOM   4969 C CB  . MET B 1 180 ? -10.79100 -16.93600 -42.55600 1.000 56.72068  ? 180 MET B CB  1 
ATOM   4970 C CG  . MET B 1 180 ? -9.69200  -17.25600 -41.57300 1.000 60.31564  ? 180 MET B CG  1 
ATOM   4971 S SD  . MET B 1 180 ? -9.27500  -19.01200 -41.62100 1.000 55.65750  ? 180 MET B SD  1 
ATOM   4972 C CE  . MET B 1 180 ? -10.83400 -19.74600 -41.16700 1.000 47.19068  ? 180 MET B CE  1 
ATOM   4973 N N   . ASP B 1 181 ? -11.48600 -17.93100 -45.62100 1.000 60.44715  ? 181 ASP B N   1 
ATOM   4974 C CA  . ASP B 1 181 ? -12.71900 -18.35100 -46.26900 1.000 56.30495  ? 181 ASP B CA  1 
ATOM   4975 C C   . ASP B 1 181 ? -13.81600 -18.49300 -45.21700 1.000 52.65186  ? 181 ASP B C   1 
ATOM   4976 O O   . ASP B 1 181 ? -13.54900 -18.75600 -44.03800 1.000 46.79532  ? 181 ASP B O   1 
ATOM   4977 C CB  . ASP B 1 181 ? -12.52700 -19.67300 -47.01900 1.000 56.13454  ? 181 ASP B CB  1 
ATOM   4978 C CG  . ASP B 1 181 ? -12.18500 -19.47100 -48.49400 1.000 69.29885  ? 181 ASP B CG  1 
ATOM   4979 O OD1 . ASP B 1 181 ? -12.09600 -18.30500 -48.94600 1.000 75.71084  ? 181 ASP B OD1 1 
ATOM   4980 O OD2 . ASP B 1 181 ? -11.99400 -20.48400 -49.20100 1.000 68.09936  ? 181 ASP B OD2 1 
ATOM   4981 N N   . GLY B 1 182 ? -15.06200 -18.28900 -45.64800 1.000 53.88656  ? 182 GLY B N   1 
ATOM   4982 C CA  . GLY B 1 182 ? -16.20800 -18.35000 -44.77200 1.000 43.66854  ? 182 GLY B CA  1 
ATOM   4983 C C   . GLY B 1 182 ? -17.17400 -19.44700 -45.18300 1.000 42.17530  ? 182 GLY B C   1 
ATOM   4984 O O   . GLY B 1 182 ? -16.97600 -20.14300 -46.18300 1.000 47.16434  ? 182 GLY B O   1 
ATOM   4985 N N   . PHE B 1 183 ? -18.22300 -19.60100 -44.36300 1.000 39.88645  ? 183 PHE B N   1 
ATOM   4986 C CA  . PHE B 1 183 ? -19.35200 -20.47000 -44.68600 1.000 41.54092  ? 183 PHE B CA  1 
ATOM   4987 C C   . PHE B 1 183 ? -20.69500 -19.83100 -44.34300 1.000 42.45689  ? 183 PHE B C   1 
ATOM   4988 O O   . PHE B 1 183 ? -21.73100 -20.50600 -44.44200 1.000 35.80502  ? 183 PHE B O   1 
ATOM   4989 C CB  . PHE B 1 183 ? -19.24500 -21.80800 -43.96000 1.000 39.08042  ? 183 PHE B CB  1 
ATOM   4990 C CG  . PHE B 1 183 ? -18.12900 -22.68600 -44.45800 1.000 42.97568  ? 183 PHE B CG  1 
ATOM   4991 C CD1 . PHE B 1 183 ? -18.30700 -23.50000 -45.55000 1.000 41.58407  ? 183 PHE B CD1 1 
ATOM   4992 C CD2 . PHE B 1 183 ? -16.90900 -22.71300 -43.80800 1.000 42.96224  ? 183 PHE B CD2 1 
ATOM   4993 C CE1 . PHE B 1 183 ? -17.28200 -24.31300 -45.99200 1.000 46.49251  ? 183 PHE B CE1 1 
ATOM   4994 C CE2 . PHE B 1 183 ? -15.89000 -23.52300 -44.24600 1.000 39.81049  ? 183 PHE B CE2 1 
ATOM   4995 C CZ  . PHE B 1 183 ? -16.07400 -24.32100 -45.33800 1.000 39.93342  ? 183 PHE B CZ  1 
ATOM   4996 N N   . LEU B 1 184 ? -20.70200 -18.56500 -43.92600 1.000 42.11850  ? 184 LEU B N   1 
ATOM   4997 C CA  . LEU B 1 184 ? -21.92900 -17.87700 -43.55900 1.000 36.45087  ? 184 LEU B CA  1 
ATOM   4998 C C   . LEU B 1 184 ? -22.99200 -18.06300 -44.62000 1.000 38.91787  ? 184 LEU B C   1 
ATOM   4999 O O   . LEU B 1 184 ? -22.76400 -17.78900 -45.80100 1.000 45.22269  ? 184 LEU B O   1 
ATOM   5000 C CB  . LEU B 1 184 ? -21.65100 -16.38500 -43.37000 1.000 39.08426  ? 184 LEU B CB  1 
ATOM   5001 C CG  . LEU B 1 184 ? -22.82200 -15.54500 -42.88800 1.000 36.52027  ? 184 LEU B CG  1 
ATOM   5002 C CD1 . LEU B 1 184 ? -23.34100 -16.04400 -41.52700 1.000 40.10753  ? 184 LEU B CD1 1 
ATOM   5003 C CD2 . LEU B 1 184 ? -22.38400 -14.10600 -42.79900 1.000 34.93488  ? 184 LEU B CD2 1 
ATOM   5004 N N   . GLY B 1 185 ? -24.15200 -18.54600 -44.19300 1.000 40.17049  ? 185 GLY B N   1 
ATOM   5005 C CA  . GLY B 1 185 ? -25.31800 -18.59500 -45.04000 1.000 36.38290  ? 185 GLY B CA  1 
ATOM   5006 C C   . GLY B 1 185 ? -25.55900 -19.91500 -45.72700 1.000 43.14798  ? 185 GLY B C   1 
ATOM   5007 O O   . GLY B 1 185 ? -26.63100 -20.10100 -46.31100 1.000 52.09882  ? 185 GLY B O   1 
ATOM   5008 N N   . MET B 1 186 ? -24.62700 -20.84900 -45.65700 1.000 43.11102  ? 186 MET B N   1 
ATOM   5009 C CA  . MET B 1 186 ? -24.79100 -22.04400 -46.46400 1.000 40.95019  ? 186 MET B CA  1 
ATOM   5010 C C   . MET B 1 186 ? -25.46500 -23.15400 -45.67200 1.000 37.90513  ? 186 MET B C   1 
ATOM   5011 O O   . MET B 1 186 ? -25.69400 -23.04900 -44.46700 1.000 38.00000  ? 186 MET B O   1 
ATOM   5012 C CB  . MET B 1 186 ? -23.44200 -22.47200 -47.00800 1.000 42.78897  ? 186 MET B CB  1 
ATOM   5013 C CG  . MET B 1 186 ? -22.67200 -21.25700 -47.48500 1.000 43.51870  ? 186 MET B CG  1 
ATOM   5014 S SD  . MET B 1 186 ? -21.26000 -21.69500 -48.47200 1.000 49.72168  ? 186 MET B SD  1 
ATOM   5015 C CE  . MET B 1 186 ? -22.03300 -22.84700 -49.60000 1.000 53.24744  ? 186 MET B CE  1 
ATOM   5016 N N   . HIS B 1 187 ? -25.82100 -24.21100 -46.38800 1.000 37.92108  ? 187 HIS B N   1 
ATOM   5017 C CA  . HIS B 1 187 ? -26.54800 -25.34100 -45.84000 1.000 38.34983  ? 187 HIS B CA  1 
ATOM   5018 C C   . HIS B 1 187 ? -25.73900 -26.60100 -46.07800 1.000 39.31063  ? 187 HIS B C   1 
ATOM   5019 O O   . HIS B 1 187 ? -24.97800 -26.69700 -47.04800 1.000 36.91491  ? 187 HIS B O   1 
ATOM   5020 C CB  . HIS B 1 187 ? -27.93800 -25.50400 -46.47700 1.000 39.18671  ? 187 HIS B CB  1 
ATOM   5021 C CG  . HIS B 1 187 ? -28.82200 -24.31700 -46.29100 1.000 40.08210  ? 187 HIS B CG  1 
ATOM   5022 N ND1 . HIS B 1 187 ? -30.08500 -24.40900 -45.74700 1.000 44.84749  ? 187 HIS B ND1 1 
ATOM   5023 C CD2 . HIS B 1 187 ? -28.62000 -23.00400 -46.55900 1.000 42.99267  ? 187 HIS B CD2 1 
ATOM   5024 C CE1 . HIS B 1 187 ? -30.62600 -23.20200 -45.69400 1.000 48.03056  ? 187 HIS B CE1 1 
ATOM   5025 N NE2 . HIS B 1 187 ? -29.75600 -22.33300 -46.18000 1.000 46.78134  ? 187 HIS B NE2 1 
ATOM   5026 N N   . PHE B 1 188 ? -25.90600 -27.56500 -45.17900 1.000 33.76733  ? 188 PHE B N   1 
ATOM   5027 C CA  . PHE B 1 188 ? -25.09600 -28.76300 -45.24700 1.000 35.07840  ? 188 PHE B CA  1 
ATOM   5028 C C   . PHE B 1 188 ? -26.00500 -29.97400 -45.11000 1.000 36.15537  ? 188 PHE B C   1 
ATOM   5029 O O   . PHE B 1 188 ? -26.97100 -29.92500 -44.34400 1.000 39.33141  ? 188 PHE B O   1 
ATOM   5030 C CB  . PHE B 1 188 ? -24.04200 -28.77900 -44.13200 1.000 32.79488  ? 188 PHE B CB  1 
ATOM   5031 C CG  . PHE B 1 188 ? -22.98600 -27.70800 -44.25600 1.000 35.57118  ? 188 PHE B CG  1 
ATOM   5032 C CD1 . PHE B 1 188 ? -23.29900 -26.36500 -44.04700 1.000 36.06608  ? 188 PHE B CD1 1 
ATOM   5033 C CD2 . PHE B 1 188 ? -21.65900 -28.05100 -44.52900 1.000 32.41767  ? 188 PHE B CD2 1 
ATOM   5034 C CE1 . PHE B 1 188 ? -22.32300 -25.37700 -44.13800 1.000 34.50001  ? 188 PHE B CE1 1 
ATOM   5035 C CE2 . PHE B 1 188 ? -20.68500 -27.08500 -44.61500 1.000 34.58699  ? 188 PHE B CE2 1 
ATOM   5036 C CZ  . PHE B 1 188 ? -21.01500 -25.73300 -44.42200 1.000 36.14087  ? 188 PHE B CZ  1 
ATOM   5037 N N   . PRO B 1 189 ? -25.72100 -31.06900 -45.82100 1.000 34.86572  ? 189 PRO B N   1 
ATOM   5038 C CA  . PRO B 1 189 ? -26.52600 -32.29000 -45.66300 1.000 38.32345  ? 189 PRO B CA  1 
ATOM   5039 C C   . PRO B 1 189 ? -26.64700 -32.72200 -44.20200 1.000 38.98992  ? 189 PRO B C   1 
ATOM   5040 O O   . PRO B 1 189 ? -25.73800 -32.51600 -43.38900 1.000 37.28089  ? 189 PRO B O   1 
ATOM   5041 C CB  . PRO B 1 189 ? -25.75200 -33.33400 -46.47500 1.000 33.86691  ? 189 PRO B CB  1 
ATOM   5042 C CG  . PRO B 1 189 ? -24.86200 -32.57900 -47.35200 1.000 31.33711  ? 189 PRO B CG  1 
ATOM   5043 C CD  . PRO B 1 189 ? -24.61500 -31.24400 -46.77500 1.000 31.91799  ? 189 PRO B CD  1 
ATOM   5044 N N   . ALA B 1 190 ? -27.78800 -33.34900 -43.88600 1.000 36.48133  ? 190 ALA B N   1 
ATOM   5045 C CA  . ALA B 1 190 ? -27.99000 -33.98900 -42.58900 1.000 37.34053  ? 190 ALA B CA  1 
ATOM   5046 C C   . ALA B 1 190 ? -26.97900 -35.09700 -42.30600 1.000 33.40939  ? 190 ALA B C   1 
ATOM   5047 O O   . ALA B 1 190 ? -26.73900 -35.41700 -41.13700 1.000 38.27003  ? 190 ALA B O   1 
ATOM   5048 C CB  . ALA B 1 190 ? -29.40300 -34.56700 -42.51700 1.000 32.61573  ? 190 ALA B CB  1 
ATOM   5049 N N   . THR B 1 191 ? -26.39400 -35.69500 -43.33900 1.000 35.29421  ? 191 THR B N   1 
ATOM   5050 C CA  . THR B 1 191 ? -25.45600 -36.80100 -43.17600 1.000 38.30913  ? 191 THR B CA  1 
ATOM   5051 C C   . THR B 1 191 ? -24.04500 -36.35700 -42.78600 1.000 38.19106  ? 191 THR B C   1 
ATOM   5052 O O   . THR B 1 191 ? -23.19700 -37.21400 -42.49900 1.000 39.75020  ? 191 THR B O   1 
ATOM   5053 C CB  . THR B 1 191 ? -25.39600 -37.62300 -44.47200 1.000 38.18973  ? 191 THR B CB  1 
ATOM   5054 O OG1 . THR B 1 191 ? -25.55800 -36.75100 -45.60800 1.000 35.72656  ? 191 THR B OG1 1 
ATOM   5055 C CG2 . THR B 1 191 ? -26.47200 -38.71500 -44.46900 1.000 30.02718  ? 191 THR B CG2 1 
ATOM   5056 N N   . ASP B 1 192 ? -23.75900 -35.05600 -42.78600 1.000 34.60766  ? 192 ASP B N   1 
ATOM   5057 C CA  . ASP B 1 192 ? -22.45800 -34.60700 -42.31700 1.000 37.30322  ? 192 ASP B CA  1 
ATOM   5058 C C   . ASP B 1 192 ? -22.29900 -34.83000 -40.82700 1.000 35.70835  ? 192 ASP B C   1 
ATOM   5059 O O   . ASP B 1 192 ? -21.16800 -34.86400 -40.33800 1.000 36.16217  ? 192 ASP B O   1 
ATOM   5060 C CB  . ASP B 1 192 ? -22.24200 -33.12900 -42.63600 1.000 34.29352  ? 192 ASP B CB  1 
ATOM   5061 C CG  . ASP B 1 192 ? -22.06600 -32.87300 -44.11400 1.000 34.23315  ? 192 ASP B CG  1 
ATOM   5062 O OD1 . ASP B 1 192 ? -22.25300 -33.81400 -44.91400 1.000 36.74481  ? 192 ASP B OD1 1 
ATOM   5063 O OD2 . ASP B 1 192 ? -21.70800 -31.73500 -44.47600 1.000 33.02486  ? 192 ASP B OD2 1 
ATOM   5064 N N   . ILE B 1 193 ? -23.40600 -34.95800 -40.10200 1.000 34.01834  ? 193 ILE B N   1 
ATOM   5065 C CA  . ILE B 1 193 ? -23.41000 -35.27300 -38.67800 1.000 33.88261  ? 193 ILE B CA  1 
ATOM   5066 C C   . ILE B 1 193 ? -24.41200 -36.40400 -38.48800 1.000 34.53101  ? 193 ILE B C   1 
ATOM   5067 O O   . ILE B 1 193 ? -25.57200 -36.13800 -38.16100 1.000 34.94924  ? 193 ILE B O   1 
ATOM   5068 C CB  . ILE B 1 193 ? -23.79400 -34.06100 -37.81300 1.000 33.25493  ? 193 ILE B CB  1 
ATOM   5069 C CG1 . ILE B 1 193 ? -23.04300 -32.80100 -38.23200 1.000 33.65079  ? 193 ILE B CG1 1 
ATOM   5070 C CG2 . ILE B 1 193 ? -23.49300 -34.33600 -36.34000 1.000 32.57900  ? 193 ILE B CG2 1 
ATOM   5071 C CD1 . ILE B 1 193 ? -23.42000 -31.60200 -37.38000 1.000 32.69261  ? 193 ILE B CD1 1 
ATOM   5072 N N   . PRO B 1 194 ? -24.01900 -37.66400 -38.66700 1.000 35.75220  ? 194 PRO B N   1 
ATOM   5073 C CA  . PRO B 1 194 ? -25.01800 -38.74400 -38.74400 1.000 39.36568  ? 194 PRO B CA  1 
ATOM   5074 C C   . PRO B 1 194 ? -25.74200 -38.98300 -37.42400 1.000 38.73312  ? 194 PRO B C   1 
ATOM   5075 O O   . PRO B 1 194 ? -25.51600 -38.25000 -36.45400 1.000 37.02123  ? 194 PRO B O   1 
ATOM   5076 C CB  . PRO B 1 194 ? -24.18900 -39.96000 -39.18600 1.000 38.16293  ? 194 PRO B CB  1 
ATOM   5077 C CG  . PRO B 1 194 ? -22.78800 -39.64800 -38.74700 1.000 40.02160  ? 194 PRO B CG  1 
ATOM   5078 C CD  . PRO B 1 194 ? -22.63700 -38.15300 -38.81400 1.000 33.78925  ? 194 PRO B CD  1 
ATOM   5079 N N   . VAL B 1 195 ? -26.60500 -40.00800 -37.36900 1.000 40.80715  ? 195 VAL B N   1 
ATOM   5080 C CA  . VAL B 1 195 ? -27.55900 -40.12000 -36.26600 1.000 38.89932  ? 195 VAL B CA  1 
ATOM   5081 C C   . VAL B 1 195 ? -26.85000 -40.47900 -34.95700 1.000 40.04864  ? 195 VAL B C   1 
ATOM   5082 O O   . VAL B 1 195 ? -27.16600 -39.93000 -33.89100 1.000 36.18622  ? 195 VAL B O   1 
ATOM   5083 C CB  . VAL B 1 195 ? -28.67500 -41.13200 -36.61000 1.000 41.37009  ? 195 VAL B CB  1 
ATOM   5084 C CG1 . VAL B 1 195 ? -29.73300 -41.14700 -35.51400 1.000 35.17797  ? 195 VAL B CG1 1 
ATOM   5085 C CG2 . VAL B 1 195 ? -29.33200 -40.78900 -37.94700 1.000 41.77881  ? 195 VAL B CG2 1 
ATOM   5086 N N   . GLN B 1 196 ? -25.89000 -41.40600 -35.00200 1.000 35.04549  ? 196 GLN B N   1 
ATOM   5087 C CA  . GLN B 1 196 ? -25.25300 -41.82200 -33.75900 1.000 33.10612  ? 196 GLN B CA  1 
ATOM   5088 C C   . GLN B 1 196 ? -24.39100 -40.72000 -33.15400 1.000 35.01508  ? 196 GLN B C   1 
ATOM   5089 O O   . GLN B 1 196 ? -24.12500 -40.75700 -31.94700 1.000 34.93344  ? 196 GLN B O   1 
ATOM   5090 C CB  . GLN B 1 196 ? -24.41000 -43.07200 -33.97800 1.000 25.88568  ? 196 GLN B CB  1 
ATOM   5091 C CG  . GLN B 1 196 ? -23.02200 -42.80600 -34.53100 1.000 33.47305  ? 196 GLN B CG  1 
ATOM   5092 C CD  . GLN B 1 196 ? -22.98900 -42.71400 -36.04300 1.000 36.17951  ? 196 GLN B CD  1 
ATOM   5093 O OE1 . GLN B 1 196 ? -23.69500 -41.90900 -36.64700 1.000 39.03839  ? 196 GLN B OE1 1 
ATOM   5094 N NE2 . GLN B 1 196 ? -22.16600 -43.55000 -36.66600 1.000 39.38312  ? 196 GLN B NE2 1 
ATOM   5095 N N   . ALA B 1 197 ? -23.95500 -39.74700 -33.96700 1.000 30.74764  ? 197 ALA B N   1 
ATOM   5096 C CA  . ALA B 1 197 ? -23.16100 -38.62700 -33.48000 1.000 33.15439  ? 197 ALA B CA  1 
ATOM   5097 C C   . ALA B 1 197 ? -24.03500 -37.59800 -32.77900 1.000 33.56540  ? 197 ALA B C   1 
ATOM   5098 O O   . ALA B 1 197 ? -23.68600 -37.10600 -31.69300 1.000 31.78803  ? 197 ALA B O   1 
ATOM   5099 C CB  . ALA B 1 197 ? -22.41300 -37.97700 -34.64500 1.000 33.90656  ? 197 ALA B CB  1 
ATOM   5100 N N   . ARG B 1 198 ? -25.16300 -37.23700 -33.40600 1.000 31.26022  ? 198 ARG B N   1 
ATOM   5101 C CA  . ARG B 1 198 ? -26.11100 -36.35600 -32.74100 1.000 32.41368  ? 198 ARG B CA  1 
ATOM   5102 C C   . ARG B 1 198 ? -26.53500 -36.96200 -31.41800 1.000 28.53250  ? 198 ARG B C   1 
ATOM   5103 O O   . ARG B 1 198 ? -26.63400 -36.25800 -30.40800 1.000 31.26803  ? 198 ARG B O   1 
ATOM   5104 C CB  . ARG B 1 198 ? -27.32700 -36.09300 -33.63600 1.000 34.30979  ? 198 ARG B CB  1 
ATOM   5105 C CG  . ARG B 1 198 ? -26.97000 -35.61800 -35.03500 1.000 37.47429  ? 198 ARG B CG  1 
ATOM   5106 C CD  . ARG B 1 198 ? -28.11800 -34.85300 -35.70000 1.000 39.94112  ? 198 ARG B CD  1 
ATOM   5107 N NE  . ARG B 1 198 ? -29.25100 -35.68700 -36.09100 1.000 40.95759  ? 198 ARG B NE  1 
ATOM   5108 C CZ  . ARG B 1 198 ? -29.29900 -36.42000 -37.19900 1.000 42.89957  ? 198 ARG B CZ  1 
ATOM   5109 N NH1 . ARG B 1 198 ? -28.25900 -36.52000 -38.00900 1.000 39.10134  ? 198 ARG B NH1 1 
ATOM   5110 N NH2 . ARG B 1 198 ? -30.42500 -37.06400 -37.50600 1.000 44.72843  ? 198 ARG B NH2 1 
ATOM   5111 N N   . ALA B 1 199 ? -26.74800 -38.27900 -31.39900 1.000 28.79845  ? 199 ALA B N   1 
ATOM   5112 C CA  . ALA B 1 199 ? -27.07000 -38.96100 -30.15200 1.000 30.95292  ? 199 ALA B CA  1 
ATOM   5113 C C   . ALA B 1 199 ? -25.99100 -38.71900 -29.10000 1.000 31.46099  ? 199 ALA B C   1 
ATOM   5114 O O   . ALA B 1 199 ? -26.29200 -38.35400 -27.95600 1.000 30.21824  ? 199 ALA B O   1 
ATOM   5115 C CB  . ALA B 1 199 ? -27.24500 -40.45300 -30.41700 1.000 29.15789  ? 199 ALA B CB  1 
ATOM   5116 N N   . LEU B 1 200 ? -24.71900 -38.90400 -29.48200 1.000 28.69667  ? 200 LEU B N   1 
ATOM   5117 C CA  . LEU B 1 200 ? -23.62500 -38.71400 -28.54300 1.000 28.66980  ? 200 LEU B CA  1 
ATOM   5118 C C   . LEU B 1 200 ? -23.54100 -37.26200 -28.10400 1.000 31.08231  ? 200 LEU B C   1 
ATOM   5119 O O   . LEU B 1 200 ? -23.36600 -36.97900 -26.90900 1.000 33.73502  ? 200 LEU B O   1 
ATOM   5120 C CB  . LEU B 1 200 ? -22.30200 -39.16700 -29.17600 1.000 33.75815  ? 200 LEU B CB  1 
ATOM   5121 C CG  . LEU B 1 200 ? -21.10400 -39.30800 -28.21900 1.000 33.30387  ? 200 LEU B CG  1 
ATOM   5122 C CD1 . LEU B 1 200 ? -21.38500 -40.38600 -27.19500 1.000 32.79276  ? 200 LEU B CD1 1 
ATOM   5123 C CD2 . LEU B 1 200 ? -19.79400 -39.62200 -28.95500 1.000 30.14543  ? 200 LEU B CD2 1 
ATOM   5124 N N   . TYR B 1 201 ? -23.68900 -36.32200 -29.05000 1.000 29.37817  ? 201 TYR B N   1 
ATOM   5125 C CA  . TYR B 1 201 ? -23.48600 -34.91300 -28.72500 1.000 29.58753  ? 201 TYR B CA  1 
ATOM   5126 C C   . TYR B 1 201 ? -24.65300 -34.33400 -27.95200 1.000 33.39836  ? 201 TYR B C   1 
ATOM   5127 O O   . TYR B 1 201 ? -24.52800 -33.22900 -27.40100 1.000 35.78804  ? 201 TYR B O   1 
ATOM   5128 C CB  . TYR B 1 201 ? -23.23600 -34.06700 -29.98800 1.000 28.45910  ? 201 TYR B CB  1 
ATOM   5129 C CG  . TYR B 1 201 ? -22.11700 -34.56700 -30.87500 1.000 33.57851  ? 201 TYR B CG  1 
ATOM   5130 C CD1 . TYR B 1 201 ? -21.13600 -35.43000 -30.37500 1.000 33.63325  ? 201 TYR B CD1 1 
ATOM   5131 C CD2 . TYR B 1 201 ? -22.03700 -34.19100 -32.22200 1.000 28.80243  ? 201 TYR B CD2 1 
ATOM   5132 C CE1 . TYR B 1 201 ? -20.11700 -35.90700 -31.18500 1.000 30.72654  ? 201 TYR B CE1 1 
ATOM   5133 C CE2 . TYR B 1 201 ? -21.00500 -34.66700 -33.04000 1.000 30.48410  ? 201 TYR B CE2 1 
ATOM   5134 C CZ  . TYR B 1 201 ? -20.05100 -35.52600 -32.50600 1.000 31.88156  ? 201 TYR B CZ  1 
ATOM   5135 O OH  . TYR B 1 201 ? -19.02900 -36.02900 -33.28400 1.000 31.16792  ? 201 TYR B OH  1 
ATOM   5136 N N   . THR B 1 202 ? -25.78300 -35.04200 -27.92500 1.000 31.10877  ? 202 THR B N   1 
ATOM   5137 C CA  . THR B 1 202 ? -26.83100 -34.73500 -26.96800 1.000 32.30345  ? 202 THR B CA  1 
ATOM   5138 C C   . THR B 1 202 ? -26.43900 -35.14900 -25.55000 1.000 29.18912  ? 202 THR B C   1 
ATOM   5139 O O   . THR B 1 202 ? -26.88400 -34.52800 -24.58600 1.000 37.92560  ? 202 THR B O   1 
ATOM   5140 C CB  . THR B 1 202 ? -28.11200 -35.42300 -27.42000 1.000 32.12470  ? 202 THR B CB  1 
ATOM   5141 O OG1 . THR B 1 202 ? -28.33600 -35.07300 -28.78200 1.000 34.54987  ? 202 THR B OG1 1 
ATOM   5142 C CG2 . THR B 1 202 ? -29.29500 -34.95000 -26.62300 1.000 33.99734  ? 202 THR B CG2 1 
ATOM   5143 N N   . ARG B 1 203 ? -25.61000 -36.18000 -25.39700 1.000 35.08219  ? 203 ARG B N   1 
ATOM   5144 C CA  . ARG B 1 203 ? -25.13100 -36.61200 -24.08400 1.000 39.24837  ? 203 ARG B CA  1 
ATOM   5145 C C   . ARG B 1 203 ? -23.84400 -35.90400 -23.67500 1.000 34.90761  ? 203 ARG B C   1 
ATOM   5146 O O   . ARG B 1 203 ? -23.76200 -35.33800 -22.58300 1.000 32.63421  ? 203 ARG B O   1 
ATOM   5147 C CB  . ARG B 1 203 ? -24.88200 -38.12500 -24.07400 1.000 39.89113  ? 203 ARG B CB  1 
ATOM   5148 C CG  . ARG B 1 203 ? -26.13000 -38.97500 -24.07600 1.000 53.25161  ? 203 ARG B CG  1 
ATOM   5149 C CD  . ARG B 1 203 ? -25.76000 -40.42900 -24.29500 1.000 57.62031  ? 203 ARG B CD  1 
ATOM   5150 N NE  . ARG B 1 203 ? -24.93300 -40.95100 -23.21300 1.000 68.39786  ? 203 ARG B NE  1 
ATOM   5151 C CZ  . ARG B 1 203 ? -23.94300 -41.81700 -23.39000 1.000 65.68783  ? 203 ARG B CZ  1 
ATOM   5152 N NH1 . ARG B 1 203 ? -23.58900 -42.22100 -24.60300 1.000 53.06649  ? 203 ARG B NH1 1 
ATOM   5153 N NH2 . ARG B 1 203 ? -23.28700 -42.28200 -22.32500 1.000 60.09388  ? 203 ARG B NH2 1 
ATOM   5154 N N   . ASN B 1 204 ? -22.82000 -35.97400 -24.53000 1.000 38.96241  ? 204 ASN B N   1 
ATOM   5155 C CA  . ASN B 1 204 ? -21.51100 -35.38700 -24.27400 1.000 36.59386  ? 204 ASN B CA  1 
ATOM   5156 C C   . ASN B 1 204 ? -21.40800 -34.12200 -25.10200 1.000 30.11095  ? 204 ASN B C   1 
ATOM   5157 O O   . ASN B 1 204 ? -21.20100 -34.21500 -26.32200 1.000 31.12609  ? 204 ASN B O   1 
ATOM   5158 C CB  . ASN B 1 204 ? -20.39600 -36.37000 -24.65200 1.000 31.89477  ? 204 ASN B CB  1 
ATOM   5159 C CG  . ASN B 1 204 ? -18.99300 -35.81700 -24.37600 1.000 39.39238  ? 204 ASN B CG  1 
ATOM   5160 O OD1 . ASN B 1 204 ? -18.78700 -34.59700 -24.29000 1.000 33.88164  ? 204 ASN B OD1 1 
ATOM   5161 N ND2 . ASN B 1 204 ? -18.01600 -36.72700 -24.23100 1.000 39.90243  ? 204 ASN B ND2 1 
ATOM   5162 N N   . PRO B 1 205 ? -21.49700 -32.93600 -24.50500 1.000 28.71504  ? 205 PRO B N   1 
ATOM   5163 C CA  . PRO B 1 205 ? -21.67300 -31.71200 -25.30600 1.000 35.15131  ? 205 PRO B CA  1 
ATOM   5164 C C   . PRO B 1 205 ? -20.39700 -31.00400 -25.75500 1.000 33.92477  ? 205 PRO B C   1 
ATOM   5165 O O   . PRO B 1 205 ? -20.46900 -29.84100 -26.16200 1.000 30.42305  ? 205 PRO B O   1 
ATOM   5166 C CB  . PRO B 1 205 ? -22.46700 -30.81500 -24.35600 1.000 32.24809  ? 205 PRO B CB  1 
ATOM   5167 C CG  . PRO B 1 205 ? -21.88700 -31.14900 -23.02200 1.000 28.54104  ? 205 PRO B CG  1 
ATOM   5168 C CD  . PRO B 1 205 ? -21.57700 -32.65300 -23.06700 1.000 35.47167  ? 205 PRO B CD  1 
ATOM   5169 N N   . LEU B 1 206 ? -19.24400 -31.67800 -25.70200 1.000 33.72821  ? 206 LEU B N   1 
ATOM   5170 C CA  . LEU B 1 206 ? -17.95200 -31.08000 -26.01400 1.000 31.14402  ? 206 LEU B CA  1 
ATOM   5171 C C   . LEU B 1 206 ? -17.12300 -32.05600 -26.82700 1.000 31.91826  ? 206 LEU B C   1 
ATOM   5172 O O   . LEU B 1 206 ? -17.22700 -33.27100 -26.64500 1.000 35.36802  ? 206 LEU B O   1 
ATOM   5173 C CB  . LEU B 1 206 ? -17.15500 -30.73900 -24.74600 1.000 39.32126  ? 206 LEU B CB  1 
ATOM   5174 C CG  . LEU B 1 206 ? -17.55800 -29.45000 -24.06300 1.000 41.35375  ? 206 LEU B CG  1 
ATOM   5175 C CD1 . LEU B 1 206 ? -16.78500 -29.23200 -22.77300 1.000 38.67382  ? 206 LEU B CD1 1 
ATOM   5176 C CD2 . LEU B 1 206 ? -17.32800 -28.34300 -25.05500 1.000 38.21510  ? 206 LEU B CD2 1 
ATOM   5177 N N   . ARG B 1 207 ? -16.27100 -31.51800 -27.69900 1.000 30.61561  ? 207 ARG B N   1 
ATOM   5178 C CA  . ARG B 1 207 ? -15.31500 -32.36000 -28.40900 1.000 30.75982  ? 207 ARG B CA  1 
ATOM   5179 C C   . ARG B 1 207 ? -14.19500 -31.49500 -28.94900 1.000 31.45192  ? 207 ARG B C   1 
ATOM   5180 O O   . ARG B 1 207 ? -14.45000 -30.47700 -29.59900 1.000 35.38289  ? 207 ARG B O   1 
ATOM   5181 C CB  . ARG B 1 207 ? -15.97300 -33.13900 -29.55300 1.000 30.28411  ? 207 ARG B CB  1 
ATOM   5182 C CG  . ARG B 1 207 ? -16.69300 -32.28400 -30.56700 1.000 30.94245  ? 207 ARG B CG  1 
ATOM   5183 C CD  . ARG B 1 207 ? -17.99200 -32.93700 -30.94600 1.000 28.27677  ? 207 ARG B CD  1 
ATOM   5184 N NE  . ARG B 1 207 ? -18.92800 -33.02500 -29.83100 1.000 30.68582  ? 207 ARG B NE  1 
ATOM   5185 C CZ  . ARG B 1 207 ? -19.97300 -32.21900 -29.64200 1.000 33.83681  ? 207 ARG B CZ  1 
ATOM   5186 N NH1 . ARG B 1 207 ? -20.20800 -31.17600 -30.43400 1.000 24.42153  ? 207 ARG B NH1 1 
ATOM   5187 N NH2 . ARG B 1 207 ? -20.80900 -32.46800 -28.63600 1.000 30.29194  ? 207 ARG B NH2 1 
ATOM   5188 N N   . LEU B 1 208 ? -12.96400 -31.90200 -28.68500 1.000 24.90405  ? 208 LEU B N   1 
ATOM   5189 C CA  . LEU B 1 208 ? -11.79500 -31.26600 -29.27600 1.000 28.53520  ? 208 LEU B CA  1 
ATOM   5190 C C   . LEU B 1 208 ? -11.09900 -32.26800 -30.18500 1.000 28.01628  ? 208 LEU B C   1 
ATOM   5191 O O   . LEU B 1 208 ? -10.86300 -33.41400 -29.79100 1.000 28.73829  ? 208 LEU B O   1 
ATOM   5192 C CB  . LEU B 1 208 ? -10.83100 -30.76000 -28.19500 1.000 27.20137  ? 208 LEU B CB  1 
ATOM   5193 C CG  . LEU B 1 208 ? -9.49600  -30.18200 -28.68900 1.000 29.92446  ? 208 LEU B CG  1 
ATOM   5194 C CD1 . LEU B 1 208 ? -9.74700  -28.85500 -29.38900 1.000 31.93083  ? 208 LEU B CD1 1 
ATOM   5195 C CD2 . LEU B 1 208 ? -8.47900  -30.03300 -27.54900 1.000 28.50825  ? 208 LEU B CD2 1 
ATOM   5196 N N   . ILE B 1 209 ? -10.79800 -31.85500 -31.40300 1.000 29.58068  ? 209 ILE B N   1 
ATOM   5197 C CA  . ILE B 1 209 ? -9.92000  -32.62300 -32.26100 1.000 29.73987  ? 209 ILE B CA  1 
ATOM   5198 C C   . ILE B 1 209 ? -8.67500  -31.76100 -32.40100 1.000 29.32779  ? 209 ILE B C   1 
ATOM   5199 O O   . ILE B 1 209 ? -8.67800  -30.76700 -33.13100 1.000 28.73483  ? 209 ILE B O   1 
ATOM   5200 C CB  . ILE B 1 209 ? -10.55800 -32.96800 -33.61400 1.000 27.91103  ? 209 ILE B CB  1 
ATOM   5201 C CG1 . ILE B 1 209 ? -11.76800 -33.90600 -33.43600 1.000 33.26303  ? 209 ILE B CG1 1 
ATOM   5202 C CG2 . ILE B 1 209 ? -9.53800  -33.66300 -34.50500 1.000 26.80931  ? 209 ILE B CG2 1 
ATOM   5203 C CD1 . ILE B 1 209 ? -13.14200 -33.22800 -33.37500 1.000 24.35362  ? 209 ILE B CD1 1 
ATOM   5204 N N   . ALA B 1 210 ? -7.62100  -32.11300 -31.65600 1.000 32.21934  ? 210 ALA B N   1 
ATOM   5205 C CA  . ALA B 1 210 ? -6.48000  -31.22200 -31.49900 1.000 29.10221  ? 210 ALA B CA  1 
ATOM   5206 C C   . ALA B 1 210 ? -5.60200  -31.16200 -32.74500 1.000 35.07698  ? 210 ALA B C   1 
ATOM   5207 O O   . ALA B 1 210 ? -4.95800  -30.13100 -32.98100 1.000 33.73789  ? 210 ALA B O   1 
ATOM   5208 C CB  . ALA B 1 210 ? -5.64900  -31.65000 -30.29200 1.000 32.21717  ? 210 ALA B CB  1 
ATOM   5209 N N   . ASP B 1 211 ? -5.59400  -32.22000 -33.55500 1.000 31.93473  ? 211 ASP B N   1 
ATOM   5210 C CA  . ASP B 1 211 ? -4.74200  -32.29100 -34.73900 1.000 36.74582  ? 211 ASP B CA  1 
ATOM   5211 C C   . ASP B 1 211 ? -5.36300  -33.29900 -35.70800 1.000 39.35572  ? 211 ASP B C   1 
ATOM   5212 O O   . ASP B 1 211 ? -5.31300  -34.50900 -35.46100 1.000 38.75672  ? 211 ASP B O   1 
ATOM   5213 C CB  . ASP B 1 211 ? -3.31900  -32.67300 -34.31900 1.000 38.70527  ? 211 ASP B CB  1 
ATOM   5214 C CG  . ASP B 1 211 ? -2.44100  -33.10400 -35.47500 1.000 43.98305  ? 211 ASP B CG  1 
ATOM   5215 O OD1 . ASP B 1 211 ? -2.79900  -32.86300 -36.65700 1.000 47.37912  ? 211 ASP B OD1 1 
ATOM   5216 O OD2 . ASP B 1 211 ? -1.37800  -33.70900 -35.18100 1.000 45.80009  ? 211 ASP B OD2 1 
ATOM   5217 N N   . ALA B 1 212 ? -5.94200  -32.81100 -36.81300 1.000 40.04830  ? 212 ALA B N   1 
ATOM   5218 C CA  . ALA B 1 212 ? -6.68800  -33.71300 -37.69700 1.000 44.45172  ? 212 ALA B CA  1 
ATOM   5219 C C   . ALA B 1 212 ? -5.79300  -34.64400 -38.51500 1.000 40.69821  ? 212 ALA B C   1 
ATOM   5220 O O   . ALA B 1 212 ? -6.31200  -35.56700 -39.15800 1.000 39.36522  ? 212 ALA B O   1 
ATOM   5221 C CB  . ALA B 1 212 ? -7.59700  -32.91400 -38.64000 1.000 31.36107  ? 212 ALA B CB  1 
ATOM   5222 N N   . ARG B 1 213 ? -4.47500  -34.43200 -38.51800 1.000 45.05308  ? 213 ARG B N   1 
ATOM   5223 C CA  . ARG B 1 213 ? -3.56800  -35.28900 -39.27400 1.000 43.57267  ? 213 ARG B CA  1 
ATOM   5224 C C   . ARG B 1 213 ? -2.91800  -36.36100 -38.41700 1.000 42.01213  ? 213 ARG B C   1 
ATOM   5225 O O   . ARG B 1 213 ? -2.31600  -37.28400 -38.97400 1.000 44.75759  ? 213 ARG B O   1 
ATOM   5226 C CB  . ARG B 1 213 ? -2.47000  -34.45300 -39.94500 1.000 45.95462  ? 213 ARG B CB  1 
ATOM   5227 C CG  . ARG B 1 213 ? -2.99700  -33.37800 -40.88100 1.000 45.96899  ? 213 ARG B CG  1 
ATOM   5228 C CD  . ARG B 1 213 ? -1.95500  -32.30600 -41.13300 1.000 55.27225  ? 213 ARG B CD  1 
ATOM   5229 N NE  . ARG B 1 213 ? -2.55000  -31.01600 -41.47600 1.000 63.33257  ? 213 ARG B NE  1 
ATOM   5230 C CZ  . ARG B 1 213 ? -2.81700  -30.04900 -40.60200 1.000 63.30210  ? 213 ARG B CZ  1 
ATOM   5231 N NH1 . ARG B 1 213 ? -2.56000  -30.19300 -39.30700 1.000 58.91204  ? 213 ARG B NH1 1 
ATOM   5232 N NH2 . ARG B 1 213 ? -3.35700  -28.91000 -41.03800 1.000 51.67152  ? 213 ARG B NH2 1 
ATOM   5233 N N   . ALA B 1 214 ? -3.03800  -36.27000 -37.09100 1.000 43.84088  ? 214 ALA B N   1 
ATOM   5234 C CA  . ALA B 1 214 ? -2.30400  -37.14500 -36.18100 1.000 41.01122  ? 214 ALA B CA  1 
ATOM   5235 C C   . ALA B 1 214 ? -2.79900  -38.58700 -36.27200 1.000 42.75565  ? 214 ALA B C   1 
ATOM   5236 O O   . ALA B 1 214 ? -3.92100  -38.86900 -36.70100 1.000 40.61493  ? 214 ALA B O   1 
ATOM   5237 C CB  . ALA B 1 214 ? -2.43400  -36.65400 -34.74300 1.000 37.56041  ? 214 ALA B CB  1 
ATOM   5238 N N   . ARG B 1 215 ? -1.93100  -39.50700 -35.87000 1.000 44.76178  ? 215 ARG B N   1 
ATOM   5239 C CA  . ARG B 1 215 ? -2.33300  -40.90100 -35.72600 1.000 47.16488  ? 215 ARG B CA  1 
ATOM   5240 C C   . ARG B 1 215 ? -3.15800  -41.05500 -34.44500 1.000 44.15106  ? 215 ARG B C   1 
ATOM   5241 O O   . ARG B 1 215 ? -2.89800  -40.36200 -33.45500 1.000 46.24875  ? 215 ARG B O   1 
ATOM   5242 C CB  . ARG B 1 215 ? -1.08500  -41.80700 -35.67100 1.000 55.21484  ? 215 ARG B CB  1 
ATOM   5243 C CG  . ARG B 1 215 ? -1.05400  -43.01500 -36.63200 1.000 58.55114  ? 215 ARG B CG  1 
ATOM   5244 C CD  . ARG B 1 215 ? -0.19300  -44.18100 -36.07800 1.000 61.79913  ? 215 ARG B CD  1 
ATOM   5245 N NE  . ARG B 1 215 ? 1.23500   -44.05900 -36.36900 1.000 76.13200  ? 215 ARG B NE  1 
ATOM   5246 C CZ  . ARG B 1 215 ? 1.88400   -44.76400 -37.29300 1.000 83.97935  ? 215 ARG B CZ  1 
ATOM   5247 N NH1 . ARG B 1 215 ? 1.26400   -45.65600 -38.04700 1.000 75.02367  ? 215 ARG B NH1 1 
ATOM   5248 N NH2 . ARG B 1 215 ? 3.19200   -44.56900 -37.46600 1.000 82.21153  ? 215 ARG B NH2 1 
ATOM   5249 N N   . PRO B 1 216 ? -4.17100  -41.91800 -34.42900 1.000 33.17567  ? 216 PRO B N   1 
ATOM   5250 C CA  . PRO B 1 216 ? -4.81800  -42.23300 -33.15500 1.000 33.75702  ? 216 PRO B CA  1 
ATOM   5251 C C   . PRO B 1 216 ? -3.95300  -43.20400 -32.37600 1.000 37.01455  ? 216 PRO B C   1 
ATOM   5252 O O   . PRO B 1 216 ? -3.30900  -44.08400 -32.96000 1.000 36.35766  ? 216 PRO B O   1 
ATOM   5253 C CB  . PRO B 1 216 ? -6.14900  -42.87600 -33.56700 1.000 28.31522  ? 216 PRO B CB  1 
ATOM   5254 C CG  . PRO B 1 216 ? -5.87600  -43.42900 -34.91400 1.000 36.91648  ? 216 PRO B CG  1 
ATOM   5255 C CD  . PRO B 1 216 ? -4.86500  -42.53400 -35.56900 1.000 37.32913  ? 216 PRO B CD  1 
ATOM   5256 N N   . VAL B 1 217 ? -3.93200  -43.02300 -31.05300 1.000 31.39037  ? 217 VAL B N   1 
ATOM   5257 C CA  . VAL B 1 217 ? -3.20700  -43.89900 -30.13100 1.000 27.13406  ? 217 VAL B CA  1 
ATOM   5258 C C   . VAL B 1 217 ? -4.12200  -45.05100 -29.72600 1.000 31.80851  ? 217 VAL B C   1 
ATOM   5259 O O   . VAL B 1 217 ? -5.24500  -44.81100 -29.25800 1.000 31.56664  ? 217 VAL B O   1 
ATOM   5260 C CB  . VAL B 1 217 ? -2.72100  -43.10300 -28.91000 1.000 27.56997  ? 217 VAL B CB  1 
ATOM   5261 C CG1 . VAL B 1 217 ? -1.97800  -43.98700 -27.93500 1.000 29.55916  ? 217 VAL B CG1 1 
ATOM   5262 C CG2 . VAL B 1 217 ? -1.82000  -41.97300 -29.36800 1.000 29.61530  ? 217 VAL B CG2 1 
ATOM   5263 N N   . PRO B 1 218 ? -3.70200  -46.30500 -29.88200 1.000 35.26486  ? 218 PRO B N   1 
ATOM   5264 C CA  . PRO B 1 218 ? -4.56300  -47.42300 -29.49400 1.000 25.57303  ? 218 PRO B CA  1 
ATOM   5265 C C   . PRO B 1 218 ? -4.48100  -47.69800 -28.00500 1.000 26.95815  ? 218 PRO B C   1 
ATOM   5266 O O   . PRO B 1 218 ? -3.53000  -47.32500 -27.32000 1.000 31.61561  ? 218 PRO B O   1 
ATOM   5267 C CB  . PRO B 1 218 ? -3.99500  -48.60500 -30.29600 1.000 29.96741  ? 218 PRO B CB  1 
ATOM   5268 C CG  . PRO B 1 218 ? -2.73300  -48.08000 -31.01200 1.000 22.45026  ? 218 PRO B CG  1 
ATOM   5269 C CD  . PRO B 1 218 ? -2.39700  -46.77700 -30.38300 1.000 26.05409  ? 218 PRO B CD  1 
ATOM   5270 N N   . LEU B 1 219 ? -5.49400  -48.39800 -27.51700 1.000 36.08006  ? 219 LEU B N   1 
ATOM   5271 C CA  . LEU B 1 219 ? -5.57600  -48.87000 -26.14100 1.000 29.98000  ? 219 LEU B CA  1 
ATOM   5272 C C   . LEU B 1 219 ? -5.06800  -50.30500 -26.04300 1.000 34.65022  ? 219 LEU B C   1 
ATOM   5273 O O   . LEU B 1 219 ? -5.08900  -51.06500 -27.01300 1.000 38.10326  ? 219 LEU B O   1 
ATOM   5274 C CB  . LEU B 1 219 ? -7.02200  -48.81000 -25.63500 1.000 31.55413  ? 219 LEU B CB  1 
ATOM   5275 C CG  . LEU B 1 219 ? -7.66500  -47.43000 -25.70100 1.000 28.55013  ? 219 LEU B CG  1 
ATOM   5276 C CD1 . LEU B 1 219 ? -9.12500  -47.48100 -25.25700 1.000 27.28744  ? 219 LEU B CD1 1 
ATOM   5277 C CD2 . LEU B 1 219 ? -6.83800  -46.48000 -24.83100 1.000 27.67605  ? 219 LEU B CD2 1 
ATOM   5278 N N   . LEU B 1 220 ? -4.65400  -50.68300 -24.83600 1.000 38.90176  ? 220 LEU B N   1 
ATOM   5279 C CA  . LEU B 1 220 ? -4.08300  -51.99000 -24.58300 1.000 32.23464  ? 220 LEU B CA  1 
ATOM   5280 C C   . LEU B 1 220 ? -4.79300  -52.62500 -23.39400 1.000 35.48016  ? 220 LEU B C   1 
ATOM   5281 O O   . LEU B 1 220 ? -4.93100  -51.97700 -22.34000 1.000 34.53827  ? 220 LEU B O   1 
ATOM   5282 C CB  . LEU B 1 220 ? -2.59100  -51.86900 -24.29900 1.000 35.13282  ? 220 LEU B CB  1 
ATOM   5283 C CG  . LEU B 1 220 ? -1.71400  -51.36700 -25.43900 1.000 44.97263  ? 220 LEU B CG  1 
ATOM   5284 C CD1 . LEU B 1 220 ? -0.25100  -51.63300 -25.09700 1.000 44.95890  ? 220 LEU B CD1 1 
ATOM   5285 C CD2 . LEU B 1 220 ? -2.10300  -52.02100 -26.76000 1.000 43.06588  ? 220 LEU B CD2 1 
ATOM   5286 N N   . PRO B 1 221 ? -5.30700  -53.85800 -23.52800 1.000 30.72187  ? 221 PRO B N   1 
ATOM   5287 C CA  . PRO B 1 221 ? -5.48200  -54.64000 -24.75900 1.000 29.93236  ? 221 PRO B CA  1 
ATOM   5288 C C   . PRO B 1 221 ? -6.53400  -53.97900 -25.65700 1.000 35.49512  ? 221 PRO B C   1 
ATOM   5289 O O   . PRO B 1 221 ? -7.22600  -53.04600 -25.22600 1.000 34.29443  ? 221 PRO B O   1 
ATOM   5290 C CB  . PRO B 1 221 ? -5.93600  -56.00600 -24.21800 1.000 32.70307  ? 221 PRO B CB  1 
ATOM   5291 C CG  . PRO B 1 221 ? -6.65600  -55.68200 -22.96100 1.000 24.14760  ? 221 PRO B CG  1 
ATOM   5292 C CD  . PRO B 1 221 ? -5.86900  -54.55400 -22.35900 1.000 27.66555  ? 221 PRO B CD  1 
ATOM   5293 N N   . PRO B 1 222 ? -6.73900  -54.41800 -26.90000 1.000 41.09306  ? 222 PRO B N   1 
ATOM   5294 C CA  . PRO B 1 222 ? -7.72600  -53.73100 -27.74300 1.000 41.44892  ? 222 PRO B CA  1 
ATOM   5295 C C   . PRO B 1 222 ? -9.16100  -54.00300 -27.33300 1.000 37.81006  ? 222 PRO B C   1 
ATOM   5296 O O   . PRO B 1 222 ? -10.05200 -53.24000 -27.72800 1.000 37.52463  ? 222 PRO B O   1 
ATOM   5297 C CB  . PRO B 1 222 ? -7.43600  -54.28000 -29.14800 1.000 38.64477  ? 222 PRO B CB  1 
ATOM   5298 C CG  . PRO B 1 222 ? -6.38000  -55.37400 -28.96100 1.000 37.33551  ? 222 PRO B CG  1 
ATOM   5299 C CD  . PRO B 1 222 ? -6.33400  -55.69200 -27.51400 1.000 35.02087  ? 222 PRO B CD  1 
ATOM   5300 N N   . VAL B 1 223 ? -9.42500  -55.06200 -26.57600 1.000 33.50973  ? 223 VAL B N   1 
ATOM   5301 C CA  . VAL B 1 223 ? -10.74200 -55.23900 -25.98800 1.000 30.43803  ? 223 VAL B CA  1 
ATOM   5302 C C   . VAL B 1 223 ? -10.61100 -55.29100 -24.47400 1.000 32.57280  ? 223 VAL B C   1 
ATOM   5303 O O   . VAL B 1 223 ? -9.61000  -55.75900 -23.92600 1.000 33.29881  ? 223 VAL B O   1 
ATOM   5304 C CB  . VAL B 1 223 ? -11.43200 -56.50300 -26.52200 1.000 30.96574  ? 223 VAL B CB  1 
ATOM   5305 C CG1 . VAL B 1 223 ? -11.45600 -56.46200 -28.04500 1.000 36.11117  ? 223 VAL B CG1 1 
ATOM   5306 C CG2 . VAL B 1 223 ? -10.71900 -57.74000 -26.03700 1.000 35.50652  ? 223 VAL B CG2 1 
ATOM   5307 N N   . VAL B 1 224 ? -11.62400 -54.76600 -23.79500 1.000 33.06679  ? 224 VAL B N   1 
ATOM   5308 C CA  . VAL B 1 224 ? -11.81400 -55.01900 -22.37000 1.000 30.27780  ? 224 VAL B CA  1 
ATOM   5309 C C   . VAL B 1 224 ? -12.07900 -56.51900 -22.22900 1.000 34.64659  ? 224 VAL B C   1 
ATOM   5310 O O   . VAL B 1 224 ? -13.06200 -57.03300 -22.79100 1.000 31.19021  ? 224 VAL B O   1 
ATOM   5311 C CB  . VAL B 1 224 ? -12.95600 -54.15200 -21.81200 1.000 34.04772  ? 224 VAL B CB  1 
ATOM   5312 C CG1 . VAL B 1 224 ? -13.07400 -54.28100 -20.29000 1.000 32.67303  ? 224 VAL B CG1 1 
ATOM   5313 C CG2 . VAL B 1 224 ? -12.74900 -52.69100 -22.21900 1.000 32.13209  ? 224 VAL B CG2 1 
ATOM   5314 N N   . PRO B 1 225 ? -11.21700 -57.26000 -21.52000 1.000 32.83647  ? 225 PRO B N   1 
ATOM   5315 C CA  . PRO B 1 225 ? -11.28100 -58.73100 -21.58700 1.000 29.74549  ? 225 PRO B CA  1 
ATOM   5316 C C   . PRO B 1 225 ? -12.61400 -59.33600 -21.17600 1.000 34.84466  ? 225 PRO B C   1 
ATOM   5317 O O   . PRO B 1 225 ? -13.04400 -60.34500 -21.75500 1.000 32.61565  ? 225 PRO B O   1 
ATOM   5318 C CB  . PRO B 1 225 ? -10.15900 -59.15600 -20.64200 1.000 30.85288  ? 225 PRO B CB  1 
ATOM   5319 C CG  . PRO B 1 225 ? -9.18700  -58.03500 -20.69500 1.000 35.29103  ? 225 PRO B CG  1 
ATOM   5320 C CD  . PRO B 1 225 ? -10.01400 -56.79000 -20.81300 1.000 33.11544  ? 225 PRO B CD  1 
ATOM   5321 N N   . ALA B 1 226 ? -13.27100 -58.78000 -20.16700 1.000 32.93943  ? 226 ALA B N   1 
ATOM   5322 C CA  . ALA B 1 226 ? -14.53900 -59.37200 -19.76600 1.000 32.46238  ? 226 ALA B CA  1 
ATOM   5323 C C   . ALA B 1 226 ? -15.62500 -59.08400 -20.79500 1.000 36.16168  ? 226 ALA B C   1 
ATOM   5324 O O   . ALA B 1 226 ? -16.58300 -59.85200 -20.90300 1.000 32.54689  ? 226 ALA B O   1 
ATOM   5325 C CB  . ALA B 1 226 ? -14.95200 -58.85800 -18.38500 1.000 33.48260  ? 226 ALA B CB  1 
ATOM   5326 N N   . LEU B 1 227 ? -15.47700 -58.01200 -21.58400 1.000 35.72305  ? 227 LEU B N   1 
ATOM   5327 C CA  . LEU B 1 227 ? -16.54600 -57.57700 -22.47800 1.000 35.38829  ? 227 LEU B CA  1 
ATOM   5328 C C   . LEU B 1 227 ? -16.42200 -58.12900 -23.88800 1.000 33.36048  ? 227 LEU B C   1 
ATOM   5329 O O   . LEU B 1 227 ? -17.44300 -58.35600 -24.53800 1.000 35.58562  ? 227 LEU B O   1 
ATOM   5330 C CB  . LEU B 1 227 ? -16.60300 -56.04800 -22.53800 1.000 30.92078  ? 227 LEU B CB  1 
ATOM   5331 C CG  . LEU B 1 227 ? -16.98100 -55.36500 -21.21300 1.000 38.16618  ? 227 LEU B CG  1 
ATOM   5332 C CD1 . LEU B 1 227 ? -17.53900 -53.95700 -21.44600 1.000 35.97271  ? 227 LEU B CD1 1 
ATOM   5333 C CD2 . LEU B 1 227 ? -17.94400 -56.19900 -20.37400 1.000 38.00518  ? 227 LEU B CD2 1 
ATOM   5334 N N   . GLY B 1 228 ? -15.21100 -58.34400 -24.38700 1.000 31.25585  ? 228 GLY B N   1 
ATOM   5335 C CA  . GLY B 1 228 ? -15.07400 -58.75700 -25.77000 1.000 34.01685  ? 228 GLY B CA  1 
ATOM   5336 C C   . GLY B 1 228 ? -15.27800 -57.66300 -26.79200 1.000 30.93338  ? 228 GLY B C   1 
ATOM   5337 O O   . GLY B 1 228 ? -15.48300 -57.95800 -27.96800 1.000 36.51000  ? 228 GLY B O   1 
ATOM   5338 N N   . ARG B 1 229 ? -15.24800 -56.40700 -26.37000 1.000 32.43153  ? 229 ARG B N   1 
ATOM   5339 C CA  . ARG B 1 229 ? -15.26500 -55.25700 -27.26900 1.000 34.56698  ? 229 ARG B CA  1 
ATOM   5340 C C   . ARG B 1 229 ? -14.40400 -54.17700 -26.63400 1.000 30.47999  ? 229 ARG B C   1 
ATOM   5341 O O   . ARG B 1 229 ? -13.99000 -54.30600 -25.48100 1.000 29.43709  ? 229 ARG B O   1 
ATOM   5342 C CB  . ARG B 1 229 ? -16.68800 -54.73200 -27.52200 1.000 27.23090  ? 229 ARG B CB  1 
ATOM   5343 C CG  . ARG B 1 229 ? -17.40900 -54.32500 -26.27300 1.000 28.98411  ? 229 ARG B CG  1 
ATOM   5344 C CD  . ARG B 1 229 ? -18.27100 -53.12800 -26.49800 1.000 31.53860  ? 229 ARG B CD  1 
ATOM   5345 N NE  . ARG B 1 229 ? -19.09100 -52.87200 -25.32100 1.000 31.77852  ? 229 ARG B NE  1 
ATOM   5346 C CZ  . ARG B 1 229 ? -18.71200 -52.14300 -24.27900 1.000 36.50311  ? 229 ARG B CZ  1 
ATOM   5347 N NH1 . ARG B 1 229 ? -17.51300 -51.57200 -24.23100 1.000 37.95358  ? 229 ARG B NH1 1 
ATOM   5348 N NH2 . ARG B 1 229 ? -19.55800 -51.97700 -23.26100 1.000 31.43099  ? 229 ARG B NH2 1 
ATOM   5349 N N   . PRO B 1 230 ? -14.09900 -53.11700 -27.37400 1.000 31.42703  ? 230 PRO B N   1 
ATOM   5350 C CA  . PRO B 1 230 ? -13.23200 -52.07400 -26.82000 1.000 28.95012  ? 230 PRO B CA  1 
ATOM   5351 C C   . PRO B 1 230 ? -13.94700 -51.24800 -25.75800 1.000 33.09108  ? 230 PRO B C   1 
ATOM   5352 O O   . PRO B 1 230 ? -15.17500 -51.27200 -25.62600 1.000 32.28145  ? 230 PRO B O   1 
ATOM   5353 C CB  . PRO B 1 230 ? -12.87100 -51.24100 -28.05200 1.000 32.31335  ? 230 PRO B CB  1 
ATOM   5354 C CG  . PRO B 1 230 ? -12.95800 -52.20400 -29.19600 1.000 39.44724  ? 230 PRO B CG  1 
ATOM   5355 C CD  . PRO B 1 230 ? -14.15700 -53.06300 -28.84600 1.000 31.86922  ? 230 PRO B CD  1 
ATOM   5356 N N   . LEU B 1 231 ? -13.14400 -50.53400 -24.96300 1.000 28.25542  ? 231 LEU B N   1 
ATOM   5357 C CA  . LEU B 1 231 ? -13.69300 -49.70100 -23.89600 1.000 28.69458  ? 231 LEU B CA  1 
ATOM   5358 C C   . LEU B 1 231 ? -14.61300 -48.60900 -24.44600 1.000 31.49692  ? 231 LEU B C   1 
ATOM   5359 O O   . LEU B 1 231 ? -14.27100 -47.91400 -25.40400 1.000 29.61478  ? 231 LEU B O   1 
ATOM   5360 C CB  . LEU B 1 231 ? -12.55800 -49.06700 -23.09900 1.000 31.51196  ? 231 LEU B CB  1 
ATOM   5361 C CG  . LEU B 1 231 ? -12.93300 -48.11600 -21.97300 1.000 30.68163  ? 231 LEU B CG  1 
ATOM   5362 C CD1 . LEU B 1 231 ? -13.79400 -48.79400 -20.90900 1.000 23.74658  ? 231 LEU B CD1 1 
ATOM   5363 C CD2 . LEU B 1 231 ? -11.66400 -47.55900 -21.38200 1.000 25.57671  ? 231 LEU B CD2 1 
ATOM   5364 N N   . ASP B 1 232 ? -15.78100 -48.43900 -23.81300 1.000 30.85616  ? 232 ASP B N   1 
ATOM   5365 C CA  . ASP B 1 232 ? -16.72100 -47.38500 -24.20200 1.000 32.52532  ? 232 ASP B CA  1 
ATOM   5366 C C   . ASP B 1 232 ? -16.13100 -46.02300 -23.85300 1.000 34.85500  ? 232 ASP B C   1 
ATOM   5367 O O   . ASP B 1 232 ? -15.96500 -45.69400 -22.67200 1.000 43.38040  ? 232 ASP B O   1 
ATOM   5368 C CB  . ASP B 1 232 ? -18.06700 -47.58500 -23.50800 1.000 31.51712  ? 232 ASP B CB  1 
ATOM   5369 C CG  . ASP B 1 232 ? -19.11000 -46.54600 -23.92600 1.000 37.03905  ? 232 ASP B CG  1 
ATOM   5370 O OD1 . ASP B 1 232 ? -18.74000 -45.44100 -24.37900 1.000 31.58496  ? 232 ASP B OD1 1 
ATOM   5371 O OD2 . ASP B 1 232 ? -20.32400 -46.82400 -23.77500 1.000 36.86647  ? 232 ASP B OD2 1 
ATOM   5372 N N   . LEU B 1 233 ? -15.86500 -45.21000 -24.87600 1.000 31.39454  ? 233 LEU B N   1 
ATOM   5373 C CA  . LEU B 1 233 ? -15.24400 -43.90100 -24.72300 1.000 31.31736  ? 233 LEU B CA  1 
ATOM   5374 C C   . LEU B 1 233 ? -16.24600 -42.74500 -24.83800 1.000 32.63842  ? 233 LEU B C   1 
ATOM   5375 O O   . LEU B 1 233 ? -15.83900 -41.60200 -25.09800 1.000 30.65865  ? 233 LEU B O   1 
ATOM   5376 C CB  . LEU B 1 233 ? -14.12700 -43.74200 -25.75800 1.000 24.87423  ? 233 LEU B CB  1 
ATOM   5377 C CG  . LEU B 1 233 ? -12.93700 -44.68200 -25.54400 1.000 28.87272  ? 233 LEU B CG  1 
ATOM   5378 C CD1 . LEU B 1 233 ? -11.99700 -44.70100 -26.73100 1.000 29.67645  ? 233 LEU B CD1 1 
ATOM   5379 C CD2 . LEU B 1 233 ? -12.17200 -44.26500 -24.30700 1.000 27.62822  ? 233 LEU B CD2 1 
ATOM   5380 N N   . SER B 1 234 ? -17.54000 -43.01200 -24.62300 1.000 33.13654  ? 234 SER B N   1 
ATOM   5381 C CA  . SER B 1 234 ? -18.57200 -41.99200 -24.83400 1.000 34.98461  ? 234 SER B CA  1 
ATOM   5382 C C   . SER B 1 234 ? -18.27600 -40.70900 -24.06800 1.000 34.25979  ? 234 SER B C   1 
ATOM   5383 O O   . SER B 1 234 ? -18.57400 -39.60800 -24.54700 1.000 36.48531  ? 234 SER B O   1 
ATOM   5384 C CB  . SER B 1 234 ? -19.94700 -42.52700 -24.42400 1.000 31.54020  ? 234 SER B CB  1 
ATOM   5385 O OG  . SER B 1 234 ? -20.31300 -43.64600 -25.21800 1.000 41.66086  ? 234 SER B OG  1 
ATOM   5386 N N   . ASN B 1 235 ? -17.70100 -40.82500 -22.87400 1.000 36.83213  ? 235 ASN B N   1 
ATOM   5387 C CA  . ASN B 1 235 ? -17.40800 -39.65400 -22.06000 1.000 35.76703  ? 235 ASN B CA  1 
ATOM   5388 C C   . ASN B 1 235 ? -15.93600 -39.29000 -22.04800 1.000 30.76697  ? 235 ASN B C   1 
ATOM   5389 O O   . ASN B 1 235 ? -15.55700 -38.34000 -21.35400 1.000 28.41819  ? 235 ASN B O   1 
ATOM   5390 C CB  . ASN B 1 235 ? -17.89300 -39.86800 -20.63200 1.000 37.78891  ? 235 ASN B CB  1 
ATOM   5391 C CG  . ASN B 1 235 ? -19.38300 -40.09700 -20.56700 1.000 38.89637  ? 235 ASN B CG  1 
ATOM   5392 O OD1 . ASN B 1 235 ? -19.83400 -41.19900 -20.24400 1.000 39.52428  ? 235 ASN B OD1 1 
ATOM   5393 N ND2 . ASN B 1 235 ? -20.16200 -39.06400 -20.90300 1.000 36.69720  ? 235 ASN B ND2 1 
ATOM   5394 N N   . SER B 1 236 ? -15.11300 -39.99800 -22.81400 1.000 28.86103  ? 236 SER B N   1 
ATOM   5395 C CA  . SER B 1 236 ? -13.68300 -39.71200 -22.85800 1.000 32.82988  ? 236 SER B CA  1 
ATOM   5396 C C   . SER B 1 236 ? -13.42000 -38.36800 -23.53500 1.000 28.82507  ? 236 SER B C   1 
ATOM   5397 O O   . SER B 1 236 ? -13.96900 -38.08100 -24.60500 1.000 30.02256  ? 236 SER B O   1 
ATOM   5398 C CB  . SER B 1 236 ? -12.95700 -40.83300 -23.59800 1.000 26.97660  ? 236 SER B CB  1 
ATOM   5399 O OG  . SER B 1 236 ? -11.77600 -40.36400 -24.22100 1.000 29.14163  ? 236 SER B OG  1 
ATOM   5400 N N   . ALA B 1 237 ? -12.59100 -37.53800 -22.89800 1.000 25.03913  ? 237 ALA B N   1 
ATOM   5401 C CA  . ALA B 1 237 ? -12.17000 -36.27600 -23.49800 1.000 26.93885  ? 237 ALA B CA  1 
ATOM   5402 C C   . ALA B 1 237 ? -11.06300 -36.47200 -24.53200 1.000 34.87802  ? 237 ALA B C   1 
ATOM   5403 O O   . ALA B 1 237 ? -10.82600 -35.57400 -25.35300 1.000 28.79379  ? 237 ALA B O   1 
ATOM   5404 C CB  . ALA B 1 237 ? -11.69200 -35.30500 -22.41100 1.000 24.05806  ? 237 ALA B CB  1 
ATOM   5405 N N   . LEU B 1 238 ? -10.36900 -37.61400 -24.50300 1.000 30.26288  ? 238 LEU B N   1 
ATOM   5406 C CA  . LEU B 1 238 ? -9.28900  -37.88300 -25.43600 1.000 26.99150  ? 238 LEU B CA  1 
ATOM   5407 C C   . LEU B 1 238 ? -9.74900  -38.71500 -26.61800 1.000 33.97306  ? 238 LEU B C   1 
ATOM   5408 O O   . LEU B 1 238 ? -8.91800  -39.07500 -27.47100 1.000 24.33440  ? 238 LEU B O   1 
ATOM   5409 C CB  . LEU B 1 238 ? -8.14600  -38.60100 -24.72000 1.000 33.67700  ? 238 LEU B CB  1 
ATOM   5410 C CG  . LEU B 1 238 ? -7.54100  -37.87700 -23.51700 1.000 31.52371  ? 238 LEU B CG  1 
ATOM   5411 C CD1 . LEU B 1 238 ? -6.49500  -38.77100 -22.88400 1.000 26.17453  ? 238 LEU B CD1 1 
ATOM   5412 C CD2 . LEU B 1 238 ? -6.95500  -36.55300 -23.96600 1.000 26.85892  ? 238 LEU B CD2 1 
ATOM   5413 N N   . ARG B 1 239 ? -11.04500 -39.04500 -26.67600 1.000 28.35194  ? 239 ARG B N   1 
ATOM   5414 C CA  . ARG B 1 239 ? -11.50800 -40.00600 -27.65800 1.000 27.53210  ? 239 ARG B CA  1 
ATOM   5415 C C   . ARG B 1 239 ? -11.16500 -39.50600 -29.04000 1.000 27.43640  ? 239 ARG B C   1 
ATOM   5416 O O   . ARG B 1 239 ? -11.41900 -38.34600 -29.36300 1.000 32.00976  ? 239 ARG B O   1 
ATOM   5417 C CB  . ARG B 1 239 ? -13.01300 -40.21100 -27.56100 1.000 28.45285  ? 239 ARG B CB  1 
ATOM   5418 C CG  . ARG B 1 239 ? -13.50600 -41.29800 -28.50500 1.000 29.71326  ? 239 ARG B CG  1 
ATOM   5419 C CD  . ARG B 1 239 ? -15.02700 -41.32000 -28.47600 1.000 29.82840  ? 239 ARG B CD  1 
ATOM   5420 N NE  . ARG B 1 239 ? -15.53300 -39.99800 -28.81600 1.000 27.38174  ? 239 ARG B NE  1 
ATOM   5421 C CZ  . ARG B 1 239 ? -16.03600 -39.68600 -30.00000 1.000 31.18813  ? 239 ARG B CZ  1 
ATOM   5422 N NH1 . ARG B 1 239 ? -16.22700 -40.61100 -30.93200 1.000 30.26709  ? 239 ARG B NH1 1 
ATOM   5423 N NH2 . ARG B 1 239 ? -16.35000 -38.41700 -30.25900 1.000 28.16862  ? 239 ARG B NH2 1 
ATOM   5424 N N   . SER B 1 240 ? -10.55300 -40.37100 -29.84000 1.000 29.12078  ? 240 SER B N   1 
ATOM   5425 C CA  . SER B 1 240 ? -10.31400 -40.06700 -31.23900 1.000 27.25986  ? 240 SER B CA  1 
ATOM   5426 C C   . SER B 1 240 ? -11.58000 -40.34300 -32.05400 1.000 28.96205  ? 240 SER B C   1 
ATOM   5427 O O   . SER B 1 240 ? -12.29600 -41.31700 -31.80500 1.000 29.16820  ? 240 SER B O   1 
ATOM   5428 C CB  . SER B 1 240 ? -9.14500  -40.89900 -31.75900 1.000 27.48891  ? 240 SER B CB  1 
ATOM   5429 O OG  . SER B 1 240 ? -9.06200  -40.75800 -33.16300 1.000 34.13440  ? 240 SER B OG  1 
ATOM   5430 N N   . VAL B 1 241 ? -11.85500 -39.47200 -33.03100 1.000 32.30391  ? 241 VAL B N   1 
ATOM   5431 C CA  . VAL B 1 241 ? -13.12500 -39.46400 -33.74300 1.000 33.71531  ? 241 VAL B CA  1 
ATOM   5432 C C   . VAL B 1 241 ? -13.06700 -40.39100 -34.94600 1.000 33.76357  ? 241 VAL B C   1 
ATOM   5433 O O   . VAL B 1 241 ? -11.99900 -40.82500 -35.37700 1.000 32.82091  ? 241 VAL B O   1 
ATOM   5434 C CB  . VAL B 1 241 ? -13.50000 -38.03700 -34.18400 1.000 33.50292  ? 241 VAL B CB  1 
ATOM   5435 C CG1 . VAL B 1 241 ? -13.75200 -37.18400 -32.96700 1.000 36.30197  ? 241 VAL B CG1 1 
ATOM   5436 C CG2 . VAL B 1 241 ? -12.39600 -37.44300 -35.02500 1.000 31.85945  ? 241 VAL B CG2 1 
ATOM   5437 N N   . SER B 1 242 ? -14.24900 -40.68000 -35.50100 1.000 36.60842  ? 242 SER B N   1 
ATOM   5438 C CA  . SER B 1 242 ? -14.39600 -41.39500 -36.76500 1.000 34.24107  ? 242 SER B CA  1 
ATOM   5439 C C   . SER B 1 242 ? -13.33000 -41.00300 -37.78000 1.000 30.53269  ? 242 SER B C   1 
ATOM   5440 O O   . SER B 1 242 ? -13.12000 -39.80600 -38.03100 1.000 32.91576  ? 242 SER B O   1 
ATOM   5441 C CB  . SER B 1 242 ? -15.76500 -41.11600 -37.38500 1.000 32.05604  ? 242 SER B CB  1 
ATOM   5442 O OG  . SER B 1 242 ? -15.81300 -41.67900 -38.68600 1.000 30.34671  ? 242 SER B OG  1 
ATOM   5443 N N   . PRO B 1 243 ? -12.66100 -41.96400 -38.41600 1.000 30.41543  ? 243 PRO B N   1 
ATOM   5444 C CA  . PRO B 1 243 ? -11.70600 -41.58300 -39.47200 1.000 33.57053  ? 243 PRO B CA  1 
ATOM   5445 C C   . PRO B 1 243 ? -12.39700 -40.98600 -40.68900 1.000 33.30936  ? 243 PRO B C   1 
ATOM   5446 O O   . PRO B 1 243 ? -11.77900 -40.20400 -41.42200 1.000 28.52590  ? 243 PRO B O   1 
ATOM   5447 C CB  . PRO B 1 243 ? -10.99200 -42.89800 -39.81000 1.000 31.40753  ? 243 PRO B CB  1 
ATOM   5448 C CG  . PRO B 1 243 ? -11.48700 -43.91100 -38.79500 1.000 36.40926  ? 243 PRO B CG  1 
ATOM   5449 C CD  . PRO B 1 243 ? -12.81700 -43.42100 -38.31200 1.000 30.39030  ? 243 PRO B CD  1 
ATOM   5450 N N   . VAL B 1 244 ? -13.67200 -41.31300 -40.91300 1.000 34.03938  ? 244 VAL B N   1 
ATOM   5451 C CA  . VAL B 1 244 ? -14.43500 -40.62600 -41.94900 1.000 29.14349  ? 244 VAL B CA  1 
ATOM   5452 C C   . VAL B 1 244 ? -14.45200 -39.12100 -41.68800 1.000 35.10044  ? 244 VAL B C   1 
ATOM   5453 O O   . VAL B 1 244 ? -14.26600 -38.31300 -42.60800 1.000 36.05859  ? 244 VAL B O   1 
ATOM   5454 C CB  . VAL B 1 244 ? -15.85700 -41.20900 -42.02800 1.000 33.33597  ? 244 VAL B CB  1 
ATOM   5455 C CG1 . VAL B 1 244 ? -16.71100 -40.42600 -43.00400 1.000 38.63435  ? 244 VAL B CG1 1 
ATOM   5456 C CG2 . VAL B 1 244 ? -15.80000 -42.65800 -42.43900 1.000 32.27833  ? 244 VAL B CG2 1 
ATOM   5457 N N   . HIS B 1 245 ? -14.65600 -38.71800 -40.42600 1.000 35.93495  ? 245 HIS B N   1 
ATOM   5458 C CA  . HIS B 1 245 ? -14.76500 -37.29200 -40.12200 1.000 27.75876  ? 245 HIS B CA  1 
ATOM   5459 C C   . HIS B 1 245 ? -13.42300 -36.58200 -40.22300 1.000 32.71401  ? 245 HIS B C   1 
ATOM   5460 O O   . HIS B 1 245 ? -13.37200 -35.42300 -40.64600 1.000 34.01083  ? 245 HIS B O   1 
ATOM   5461 C CB  . HIS B 1 245 ? -15.35400 -37.06000 -38.73300 1.000 29.09644  ? 245 HIS B CB  1 
ATOM   5462 C CG  . HIS B 1 245 ? -15.44300 -35.60500 -38.37400 1.000 35.57849  ? 245 HIS B CG  1 
ATOM   5463 N ND1 . HIS B 1 245 ? -16.17400 -34.69600 -39.11700 1.000 28.90245  ? 245 HIS B ND1 1 
ATOM   5464 C CD2 . HIS B 1 245 ? -14.84700 -34.89100 -37.39000 1.000 35.36265  ? 245 HIS B CD2 1 
ATOM   5465 C CE1 . HIS B 1 245 ? -16.03900 -33.49400 -38.58900 1.000 30.50422  ? 245 HIS B CE1 1 
ATOM   5466 N NE2 . HIS B 1 245 ? -15.22800 -33.58200 -37.55100 1.000 31.92700  ? 245 HIS B NE2 1 
ATOM   5467 N N   . LEU B 1 246 ? -12.33500 -37.24800 -39.83600 1.000 32.55150  ? 246 LEU B N   1 
ATOM   5468 C CA  . LEU B 1 246 ? -11.00800 -36.68000 -40.04500 1.000 32.31054  ? 246 LEU B CA  1 
ATOM   5469 C C   . LEU B 1 246 ? -10.75600 -36.38000 -41.52100 1.000 38.18661  ? 246 LEU B C   1 
ATOM   5470 O O   . LEU B 1 246 ? -10.16800 -35.34700 -41.86700 1.000 40.43731  ? 246 LEU B O   1 
ATOM   5471 C CB  . LEU B 1 246 ? -9.96200  -37.64200 -39.49200 1.000 31.73640  ? 246 LEU B CB  1 
ATOM   5472 C CG  . LEU B 1 246 ? -10.09700 -37.75700 -37.96800 1.000 34.16461  ? 246 LEU B CG  1 
ATOM   5473 C CD1 . LEU B 1 246 ? -9.15200  -38.78900 -37.40000 1.000 29.21801  ? 246 LEU B CD1 1 
ATOM   5474 C CD2 . LEU B 1 246 ? -9.88000  -36.38900 -37.31300 1.000 31.76516  ? 246 LEU B CD2 1 
ATOM   5475 N N   . GLU B 1 247 ? -11.21200 -37.26100 -42.40700 1.000 38.32230  ? 247 GLU B N   1 
ATOM   5476 C CA  . GLU B 1 247 ? -11.05100 -37.02300 -43.83600 1.000 40.15700  ? 247 GLU B CA  1 
ATOM   5477 C C   . GLU B 1 247 ? -11.86800 -35.82800 -44.29900 1.000 34.93849  ? 247 GLU B C   1 
ATOM   5478 O O   . GLU B 1 247 ? -11.46900 -35.11800 -45.22800 1.000 37.74498  ? 247 GLU B O   1 
ATOM   5479 C CB  . GLU B 1 247 ? -11.45000 -38.27800 -44.60800 1.000 36.55784  ? 247 GLU B CB  1 
ATOM   5480 C CG  . GLU B 1 247 ? -11.11800 -38.19600 -46.06700 1.000 46.96370  ? 247 GLU B CG  1 
ATOM   5481 C CD  . GLU B 1 247 ? -11.42700 -39.47600 -46.78900 1.000 44.38487  ? 247 GLU B CD  1 
ATOM   5482 O OE1 . GLU B 1 247 ? -11.66700 -40.49300 -46.10300 1.000 39.89401  ? 247 GLU B OE1 1 
ATOM   5483 O OE2 . GLU B 1 247 ? -11.42400 -39.45200 -48.04000 1.000 54.05225  ? 247 GLU B OE2 1 
ATOM   5484 N N   . TYR B 1 248 ? -13.00500 -35.59000 -43.65500 1.000 33.34217  ? 248 TYR B N   1 
ATOM   5485 C CA  . TYR B 1 248 ? -13.83300 -34.42500 -43.95600 1.000 38.06827  ? 248 TYR B CA  1 
ATOM   5486 C C   . TYR B 1 248 ? -13.12000 -33.13300 -43.56200 1.000 40.26883  ? 248 TYR B C   1 
ATOM   5487 O O   . TYR B 1 248 ? -13.08000 -32.16600 -44.33800 1.000 40.37955  ? 248 TYR B O   1 
ATOM   5488 C CB  . TYR B 1 248 ? -15.15400 -34.61900 -43.21600 1.000 35.11178  ? 248 TYR B CB  1 
ATOM   5489 C CG  . TYR B 1 248 ? -16.27000 -33.60800 -43.28500 1.000 36.22846  ? 248 TYR B CG  1 
ATOM   5490 C CD1 . TYR B 1 248 ? -16.24300 -32.45500 -42.50700 1.000 35.27567  ? 248 TYR B CD1 1 
ATOM   5491 C CD2 . TYR B 1 248 ? -17.43900 -33.89000 -44.00700 1.000 39.15376  ? 248 TYR B CD2 1 
ATOM   5492 C CE1 . TYR B 1 248 ? -17.32300 -31.55700 -42.50800 1.000 39.48701  ? 248 TYR B CE1 1 
ATOM   5493 C CE2 . TYR B 1 248 ? -18.51000 -33.00900 -44.01900 1.000 37.20817  ? 248 TYR B CE2 1 
ATOM   5494 C CZ  . TYR B 1 248 ? -18.44800 -31.84200 -43.26900 1.000 36.75916  ? 248 TYR B CZ  1 
ATOM   5495 O OH  . TYR B 1 248 ? -19.52000 -30.97600 -43.26900 1.000 34.64478  ? 248 TYR B OH  1 
ATOM   5496 N N   . LEU B 1 249 ? -12.51700 -33.11500 -42.37100 1.000 37.47189  ? 249 LEU B N   1 
ATOM   5497 C CA  . LEU B 1 249 ? -11.76300 -31.94700 -41.93100 1.000 39.54876  ? 249 LEU B CA  1 
ATOM   5498 C C   . LEU B 1 249 ? -10.62700 -31.61900 -42.89200 1.000 39.62773  ? 249 LEU B C   1 
ATOM   5499 O O   . LEU B 1 249 ? -10.38400 -30.44900 -43.20700 1.000 36.28524  ? 249 LEU B O   1 
ATOM   5500 C CB  . LEU B 1 249 ? -11.21500 -32.19800 -40.52900 1.000 35.94803  ? 249 LEU B CB  1 
ATOM   5501 C CG  . LEU B 1 249 ? -12.35000 -32.26900 -39.52100 1.000 38.85685  ? 249 LEU B CG  1 
ATOM   5502 C CD1 . LEU B 1 249 ? -11.83800 -32.59200 -38.09300 1.000 35.60825  ? 249 LEU B CD1 1 
ATOM   5503 C CD2 . LEU B 1 249 ? -13.12400 -30.94900 -39.58500 1.000 31.37907  ? 249 LEU B CD2 1 
ATOM   5504 N N   . ARG B 1 250 ? -9.90800  -32.63900 -43.35600 1.000 42.15604  ? 250 ARG B N   1 
ATOM   5505 C CA  . ARG B 1 250 ? -8.78700  -32.38300 -44.25300 1.000 45.34809  ? 250 ARG B CA  1 
ATOM   5506 C C   . ARG B 1 250 ? -9.27900  -31.95400 -45.63100 1.000 41.13364  ? 250 ARG B C   1 
ATOM   5507 O O   . ARG B 1 250 ? -8.69900  -31.05600 -46.25300 1.000 35.89821  ? 250 ARG B O   1 
ATOM   5508 C CB  . ARG B 1 250 ? -7.88700  -33.62000 -44.32000 1.000 44.72526  ? 250 ARG B CB  1 
ATOM   5509 C CG  . ARG B 1 250 ? -7.36500  -34.03800 -42.93300 1.000 45.62230  ? 250 ARG B CG  1 
ATOM   5510 C CD  . ARG B 1 250 ? -6.27700  -35.09200 -43.00300 1.000 52.48588  ? 250 ARG B CD  1 
ATOM   5511 N NE  . ARG B 1 250 ? -6.60900  -36.15100 -43.95200 1.000 62.52058  ? 250 ARG B NE  1 
ATOM   5512 C CZ  . ARG B 1 250 ? -6.94400  -37.39400 -43.62400 1.000 57.41839  ? 250 ARG B CZ  1 
ATOM   5513 N NH1 . ARG B 1 250 ? -6.96300  -37.79700 -42.36300 1.000 57.10157  ? 250 ARG B NH1 1 
ATOM   5514 N NH2 . ARG B 1 250 ? -7.26800  -38.25600 -44.58700 1.000 60.55843  ? 250 ARG B NH2 1 
ATOM   5515 N N   . ASN B 1 251 ? -10.38400 -32.54000 -46.10300 1.000 42.82068  ? 251 ASN B N   1 
ATOM   5516 C CA  . ASN B 1 251 ? -11.00300 -32.03900 -47.32600 1.000 38.22906  ? 251 ASN B CA  1 
ATOM   5517 C C   . ASN B 1 251 ? -11.41600 -30.58300 -47.21300 1.000 38.38421  ? 251 ASN B C   1 
ATOM   5518 O O   . ASN B 1 251 ? -11.55500 -29.91400 -48.24100 1.000 42.82155  ? 251 ASN B O   1 
ATOM   5519 C CB  . ASN B 1 251 ? -12.22000 -32.87800 -47.68800 1.000 41.71961  ? 251 ASN B CB  1 
ATOM   5520 C CG  . ASN B 1 251 ? -11.84500 -34.12800 -48.42800 1.000 43.88518  ? 251 ASN B CG  1 
ATOM   5521 O OD1 . ASN B 1 251 ? -10.66300 -34.45300 -48.54200 1.000 39.04451  ? 251 ASN B OD1 1 
ATOM   5522 N ND2 . ASN B 1 251 ? -12.84500 -34.84100 -48.94500 1.000 40.93446  ? 251 ASN B ND2 1 
ATOM   5523 N N   . MET B 1 252 ? -11.61300 -30.08300 -45.99400 1.000 40.55494  ? 252 MET B N   1 
ATOM   5524 C CA  . MET B 1 252 ? -12.02400 -28.70500 -45.75000 1.000 38.04841  ? 252 MET B CA  1 
ATOM   5525 C C   . MET B 1 252 ? -10.85600 -27.74200 -45.56500 1.000 43.76278  ? 252 MET B C   1 
ATOM   5526 O O   . MET B 1 252 ? -11.07200 -26.52200 -45.55500 1.000 43.65504  ? 252 MET B O   1 
ATOM   5527 C CB  . MET B 1 252 ? -12.89600 -28.63900 -44.50600 1.000 38.31859  ? 252 MET B CB  1 
ATOM   5528 C CG  . MET B 1 252 ? -14.30400 -28.24800 -44.76500 1.000 42.33101  ? 252 MET B CG  1 
ATOM   5529 S SD  . MET B 1 252 ? -15.11200 -27.98700 -43.18700 1.000 44.98143  ? 252 MET B SD  1 
ATOM   5530 C CE  . MET B 1 252 ? -16.83400 -27.98600 -43.67800 1.000 42.78395  ? 252 MET B CE  1 
ATOM   5531 N N   . GLY B 1 253 ? -9.63200  -28.24600 -45.42100 1.000 37.82579  ? 253 GLY B N   1 
ATOM   5532 C CA  . GLY B 1 253 ? -8.52200  -27.39500 -45.07200 1.000 33.16476  ? 253 GLY B CA  1 
ATOM   5533 C C   . GLY B 1 253 ? -8.31800  -27.20100 -43.59000 1.000 40.87078  ? 253 GLY B C   1 
ATOM   5534 O O   . GLY B 1 253 ? -7.40600  -26.45400 -43.20200 1.000 50.16946  ? 253 GLY B O   1 
ATOM   5535 N N   . VAL B 1 254 ? -9.11400  -27.87400 -42.74900 1.000 40.14858  ? 254 VAL B N   1 
ATOM   5536 C CA  . VAL B 1 254 ? -9.09500  -27.66700 -41.30600 1.000 37.00065  ? 254 VAL B CA  1 
ATOM   5537 C C   . VAL B 1 254 ? -7.96000  -28.47700 -40.69500 1.000 35.62480  ? 254 VAL B C   1 
ATOM   5538 O O   . VAL B 1 254 ? -7.67200  -29.60000 -41.12900 1.000 40.50278  ? 254 VAL B O   1 
ATOM   5539 C CB  . VAL B 1 254 ? -10.46400 -28.04400 -40.70800 1.000 35.88475  ? 254 VAL B CB  1 
ATOM   5540 C CG1 . VAL B 1 254 ? -10.45400 -27.98500 -39.18300 1.000 33.49642  ? 254 VAL B CG1 1 
ATOM   5541 C CG2 . VAL B 1 254 ? -11.51500 -27.10200 -41.24000 1.000 40.25458  ? 254 VAL B CG2 1 
ATOM   5542 N N   . GLY B 1 255 ? -7.29400  -27.90600 -39.69600 1.000 35.10698  ? 255 GLY B N   1 
ATOM   5543 C CA  . GLY B 1 255 ? -6.22400  -28.61700 -39.01500 1.000 39.39034  ? 255 GLY B CA  1 
ATOM   5544 C C   . GLY B 1 255 ? -6.55200  -28.98900 -37.58300 1.000 34.76050  ? 255 GLY B C   1 
ATOM   5545 O O   . GLY B 1 255 ? -6.07000  -30.00400 -37.08100 1.000 38.96248  ? 255 GLY B O   1 
ATOM   5546 N N   . ALA B 1 256 ? -7.34200  -28.15400 -36.91000 1.000 36.61425  ? 256 ALA B N   1 
ATOM   5547 C CA  . ALA B 1 256 ? -7.86300  -28.43700 -35.58000 1.000 33.72530  ? 256 ALA B CA  1 
ATOM   5548 C C   . ALA B 1 256 ? -9.33900  -28.06500 -35.55400 1.000 32.19531  ? 256 ALA B C   1 
ATOM   5549 O O   . ALA B 1 256 ? -9.77000  -27.13200 -36.23800 1.000 37.46272  ? 256 ALA B O   1 
ATOM   5550 C CB  . ALA B 1 256 ? -7.09100  -27.67100 -34.49100 1.000 33.61357  ? 256 ALA B CB  1 
ATOM   5551 N N   . SER B 1 257 ? -10.11800 -28.79500 -34.76000 1.000 33.54110  ? 257 SER B N   1 
ATOM   5552 C CA  . SER B 1 257 ? -11.56200 -28.57900 -34.71000 1.000 32.16507  ? 257 SER B CA  1 
ATOM   5553 C C   . SER B 1 257 ? -12.08600 -28.78500 -33.29400 1.000 31.38354  ? 257 SER B C   1 
ATOM   5554 O O   . SER B 1 257 ? -11.72500 -29.76400 -32.62300 1.000 32.20689  ? 257 SER B O   1 
ATOM   5555 C CB  . SER B 1 257 ? -12.29500 -29.52100 -35.66200 1.000 33.12910  ? 257 SER B CB  1 
ATOM   5556 O OG  . SER B 1 257 ? -13.68700 -29.46900 -35.41100 1.000 30.85360  ? 257 SER B OG  1 
ATOM   5557 N N   . PHE B 1 258 ? -12.95500 -27.86900 -32.86400 1.000 25.95312  ? 258 PHE B N   1 
ATOM   5558 C CA  . PHE B 1 258 ? -13.52500 -27.85400 -31.52100 1.000 29.19440  ? 258 PHE B CA  1 
ATOM   5559 C C   . PHE B 1 258 ? -14.97700 -27.41900 -31.64700 1.000 31.87041  ? 258 PHE B C   1 
ATOM   5560 O O   . PHE B 1 258 ? -15.24700 -26.36000 -32.21700 1.000 33.01265  ? 258 PHE B O   1 
ATOM   5561 C CB  . PHE B 1 258 ? -12.75100 -26.89800 -30.60400 1.000 29.73164  ? 258 PHE B CB  1 
ATOM   5562 C CG  . PHE B 1 258 ? -13.43700 -26.62700 -29.29500 1.000 28.89886  ? 258 PHE B CG  1 
ATOM   5563 C CD1 . PHE B 1 258 ? -13.91700 -27.65700 -28.52400 1.000 32.73368  ? 258 PHE B CD1 1 
ATOM   5564 C CD2 . PHE B 1 258 ? -13.56700 -25.35100 -28.82500 1.000 30.32190  ? 258 PHE B CD2 1 
ATOM   5565 C CE1 . PHE B 1 258 ? -14.54500 -27.40600 -27.31300 1.000 34.31992  ? 258 PHE B CE1 1 
ATOM   5566 C CE2 . PHE B 1 258 ? -14.19100 -25.09700 -27.60800 1.000 33.66069  ? 258 PHE B CE2 1 
ATOM   5567 C CZ  . PHE B 1 258 ? -14.67900 -26.12700 -26.86100 1.000 32.67538  ? 258 PHE B CZ  1 
ATOM   5568 N N   . SER B 1 259 ? -15.91100 -28.22500 -31.13700 1.000 30.47242  ? 259 SER B N   1 
ATOM   5569 C CA  . SER B 1 259 ? -17.32100 -27.89400 -31.26200 1.000 28.84890  ? 259 SER B CA  1 
ATOM   5570 C C   . SER B 1 259 ? -18.05400 -28.18400 -29.95700 1.000 30.07138  ? 259 SER B C   1 
ATOM   5571 O O   . SER B 1 259 ? -17.64800 -29.04800 -29.17500 1.000 31.35371  ? 259 SER B O   1 
ATOM   5572 C CB  . SER B 1 259 ? -17.96700 -28.66500 -32.40500 1.000 27.30768  ? 259 SER B CB  1 
ATOM   5573 O OG  . SER B 1 259 ? -18.34600 -29.95600 -31.96400 1.000 30.89958  ? 259 SER B OG  1 
ATOM   5574 N N   . LEU B 1 260 ? -19.14500 -27.44400 -29.73600 1.000 30.53309  ? 260 LEU B N   1 
ATOM   5575 C CA  . LEU B 1 260 ? -19.96500 -27.53200 -28.53600 1.000 30.51690  ? 260 LEU B CA  1 
ATOM   5576 C C   . LEU B 1 260 ? -21.43400 -27.59900 -28.93700 1.000 30.79460  ? 260 LEU B C   1 
ATOM   5577 O O   . LEU B 1 260 ? -21.86600 -26.89700 -29.86000 1.000 27.24946  ? 260 LEU B O   1 
ATOM   5578 C CB  . LEU B 1 260 ? -19.74600 -26.31900 -27.60200 1.000 27.34214  ? 260 LEU B CB  1 
ATOM   5579 C CG  . LEU B 1 260 ? -18.35000 -25.68200 -27.45000 1.000 33.44160  ? 260 LEU B CG  1 
ATOM   5580 C CD1 . LEU B 1 260 ? -18.10700 -24.59200 -28.48300 1.000 30.07924  ? 260 LEU B CD1 1 
ATOM   5581 C CD2 . LEU B 1 260 ? -18.17900 -25.11100 -26.07500 1.000 36.12383  ? 260 LEU B CD2 1 
ATOM   5582 N N   . SER B 1 261 ? -22.20400 -28.42500 -28.22500 1.000 36.04600  ? 261 SER B N   1 
ATOM   5583 C CA  . SER B 1 261 ? -23.62800 -28.59200 -28.51300 1.000 29.97456  ? 261 SER B CA  1 
ATOM   5584 C C   . SER B 1 261 ? -24.43000 -27.46500 -27.87900 1.000 29.63035  ? 261 SER B C   1 
ATOM   5585 O O   . SER B 1 261 ? -24.25400 -27.16300 -26.69600 1.000 35.57058  ? 261 SER B O   1 
ATOM   5586 C CB  . SER B 1 261 ? -24.12800 -29.93900 -27.98500 1.000 27.29644  ? 261 SER B CB  1 
ATOM   5587 O OG  . SER B 1 261 ? -23.43400 -31.02700 -28.57900 1.000 31.32137  ? 261 SER B OG  1 
ATOM   5588 N N   . LEU B 1 262 ? -25.31100 -26.84300 -28.65800 1.000 32.94269  ? 262 LEU B N   1 
ATOM   5589 C CA  . LEU B 1 262 ? -26.32400 -25.94200 -28.10900 1.000 32.69677  ? 262 LEU B CA  1 
ATOM   5590 C C   . LEU B 1 262 ? -27.56800 -26.75500 -27.78500 1.000 32.12480  ? 262 LEU B C   1 
ATOM   5591 O O   . LEU B 1 262 ? -28.26800 -27.20900 -28.69200 1.000 35.08225  ? 262 LEU B O   1 
ATOM   5592 C CB  . LEU B 1 262 ? -26.68100 -24.83100 -29.09100 1.000 30.89528  ? 262 LEU B CB  1 
ATOM   5593 C CG  . LEU B 1 262 ? -25.63200 -23.78900 -29.44600 1.000 33.07926  ? 262 LEU B CG  1 
ATOM   5594 C CD1 . LEU B 1 262 ? -26.07400 -23.04900 -30.67500 1.000 33.57112  ? 262 LEU B CD1 1 
ATOM   5595 C CD2 . LEU B 1 262 ? -25.37300 -22.81500 -28.29200 1.000 37.43789  ? 262 LEU B CD2 1 
ATOM   5596 N N   . LEU B 1 263 ? -27.85200 -26.93200 -26.50000 1.000 34.41395  ? 263 LEU B N   1 
ATOM   5597 C CA  . LEU B 1 263 ? -29.06800 -27.59900 -26.04900 1.000 36.41961  ? 263 LEU B CA  1 
ATOM   5598 C C   . LEU B 1 263 ? -29.98000 -26.54000 -25.45500 1.000 47.91724  ? 263 LEU B C   1 
ATOM   5599 O O   . LEU B 1 263 ? -29.60000 -25.86500 -24.48900 1.000 51.80327  ? 263 LEU B O   1 
ATOM   5600 C CB  . LEU B 1 263 ? -28.74500 -28.67900 -25.02500 1.000 39.77858  ? 263 LEU B CB  1 
ATOM   5601 C CG  . LEU B 1 263 ? -27.76100 -29.69500 -25.60200 1.000 41.68887  ? 263 LEU B CG  1 
ATOM   5602 C CD1 . LEU B 1 263 ? -27.02700 -30.44000 -24.49600 1.000 33.37672  ? 263 LEU B CD1 1 
ATOM   5603 C CD2 . LEU B 1 263 ? -28.49800 -30.65900 -26.54700 1.000 34.95215  ? 263 LEU B CD2 1 
ATOM   5604 N N   . LYS B 1 264 ? -31.16500 -26.37800 -26.03700 1.000 46.21110  ? 264 LYS B N   1 
ATOM   5605 C CA  . LYS B 1 264 ? -32.00000 -25.21700 -25.71400 1.000 52.23557  ? 264 LYS B CA  1 
ATOM   5606 C C   . LYS B 1 264 ? -32.94600 -25.54200 -24.56000 1.000 65.47813  ? 264 LYS B C   1 
ATOM   5607 O O   . LYS B 1 264 ? -32.81100 -24.99200 -23.46200 1.000 74.05197  ? 264 LYS B O   1 
ATOM   5608 C CB  . LYS B 1 264 ? -32.75100 -24.75700 -26.96300 1.000 52.46758  ? 264 LYS B CB  1 
ATOM   5609 C CG  . LYS B 1 264 ? -33.29800 -23.35000 -26.87100 1.000 48.55645  ? 264 LYS B CG  1 
ATOM   5610 C CD  . LYS B 1 264 ? -34.44900 -23.18100 -27.84400 1.000 56.22077  ? 264 LYS B CD  1 
ATOM   5611 C CE  . LYS B 1 264 ? -34.60400 -21.73600 -28.21600 1.000 52.94362  ? 264 LYS B CE  1 
ATOM   5612 N NZ  . LYS B 1 264 ? -33.28000 -21.19000 -28.65700 1.000 52.83004  ? 264 LYS B NZ  1 
ATOM   5613 N N   . GLU B 1 265 ? -33.91700 -26.42600 -24.80300 1.000 56.42133  ? 265 GLU B N   1 
ATOM   5614 C CA  . GLU B 1 265 ? -34.79300 -26.94700 -23.74900 1.000 66.50502  ? 265 GLU B CA  1 
ATOM   5615 C C   . GLU B 1 265 ? -34.77400 -28.46700 -23.80800 1.000 56.20263  ? 265 GLU B C   1 
ATOM   5616 O O   . GLU B 1 265 ? -35.79100 -29.11700 -24.04200 1.000 58.46948  ? 265 GLU B O   1 
ATOM   5617 C CB  . GLU B 1 265 ? -36.22400 -26.42200 -23.86300 1.000 68.75157  ? 265 GLU B CB  1 
ATOM   5618 C CG  . GLU B 1 265 ? -36.35600 -24.96800 -23.47400 1.000 67.23864  ? 265 GLU B CG  1 
ATOM   5619 C CD  . GLU B 1 265 ? -37.67000 -24.37800 -23.92300 1.000 82.96728  ? 265 GLU B CD  1 
ATOM   5620 O OE1 . GLU B 1 265 ? -38.71700 -25.02200 -23.67700 1.000 92.93932  ? 265 GLU B OE1 1 
ATOM   5621 O OE2 . GLU B 1 265 ? -37.65400 -23.28000 -24.53500 1.000 80.78216  ? 265 GLU B OE2 1 
ATOM   5622 N N   . GLY B 1 266 ? -33.58000 -29.03200 -23.60800 1.000 58.57141  ? 266 GLY B N   1 
ATOM   5623 C CA  . GLY B 1 266 ? -33.37100 -30.46400 -23.67000 1.000 55.45488  ? 266 GLY B CA  1 
ATOM   5624 C C   . GLY B 1 266 ? -33.15400 -31.03900 -25.06000 1.000 58.62550  ? 266 GLY B C   1 
ATOM   5625 O O   . GLY B 1 266 ? -32.74600 -32.20400 -25.17000 1.000 58.60472  ? 266 GLY B O   1 
ATOM   5626 N N   . VAL B 1 267 ? -33.40100 -30.28000 -26.12300 1.000 53.08124  ? 267 VAL B N   1 
ATOM   5627 C CA  . VAL B 1 267 ? -33.22600 -30.78200 -27.47300 1.000 51.54090  ? 267 VAL B CA  1 
ATOM   5628 C C   . VAL B 1 267 ? -31.95600 -30.18800 -28.07800 1.000 47.65104  ? 267 VAL B C   1 
ATOM   5629 O O   . VAL B 1 267 ? -31.37700 -29.23100 -27.56100 1.000 45.97472  ? 267 VAL B O   1 
ATOM   5630 C CB  . VAL B 1 267 ? -34.48300 -30.52400 -28.35500 1.000 54.02923  ? 267 VAL B CB  1 
ATOM   5631 C CG1 . VAL B 1 267 ? -35.75800 -30.84100 -27.57200 1.000 61.54066  ? 267 VAL B CG1 1 
ATOM   5632 C CG2 . VAL B 1 267 ? -34.52700 -29.10900 -28.89500 1.000 50.51691  ? 267 VAL B CG2 1 
ATOM   5633 N N   . LEU B 1 268 ? -31.51100 -30.77600 -29.19000 1.000 45.88142  ? 268 LEU B N   1 
ATOM   5634 C CA  . LEU B 1 268 ? -30.24500 -30.43300 -29.83900 1.000 43.26874  ? 268 LEU B CA  1 
ATOM   5635 C C   . LEU B 1 268 ? -30.51100 -29.35400 -30.88400 1.000 42.31022  ? 268 LEU B C   1 
ATOM   5636 O O   . LEU B 1 268 ? -30.81600 -29.63900 -32.04400 1.000 38.49055  ? 268 LEU B O   1 
ATOM   5637 C CB  . LEU B 1 268 ? -29.61900 -31.67500 -30.46200 1.000 38.88026  ? 268 LEU B CB  1 
ATOM   5638 C CG  . LEU B 1 268 ? -28.25200 -31.52800 -31.12900 1.000 41.82876  ? 268 LEU B CG  1 
ATOM   5639 C CD1 . LEU B 1 268 ? -27.18400 -31.05400 -30.13700 1.000 37.68002  ? 268 LEU B CD1 1 
ATOM   5640 C CD2 . LEU B 1 268 ? -27.85900 -32.83400 -31.78600 1.000 37.41277  ? 268 LEU B CD2 1 
ATOM   5641 N N   . TRP B 1 269 ? -30.40100 -28.09100 -30.46200 1.000 40.62826  ? 269 TRP B N   1 
ATOM   5642 C CA  . TRP B 1 269 ? -30.74600 -26.97900 -31.34000 1.000 31.78683  ? 269 TRP B CA  1 
ATOM   5643 C C   . TRP B 1 269 ? -29.72400 -26.82300 -32.45800 1.000 32.74802  ? 269 TRP B C   1 
ATOM   5644 O O   . TRP B 1 269 ? -30.08800 -26.57600 -33.61200 1.000 35.68224  ? 269 TRP B O   1 
ATOM   5645 C CB  . TRP B 1 269 ? -30.85100 -25.70000 -30.51400 1.000 34.59207  ? 269 TRP B CB  1 
ATOM   5646 C CG  . TRP B 1 269 ? -31.43100 -24.51300 -31.22200 1.000 39.53178  ? 269 TRP B CG  1 
ATOM   5647 C CD1 . TRP B 1 269 ? -32.75400 -24.20700 -31.35400 1.000 44.86611  ? 269 TRP B CD1 1 
ATOM   5648 C CD2 . TRP B 1 269 ? -30.70900 -23.43600 -31.84800 1.000 39.51764  ? 269 TRP B CD2 1 
ATOM   5649 N NE1 . TRP B 1 269 ? -32.90200 -23.02100 -32.03700 1.000 45.74330  ? 269 TRP B NE1 1 
ATOM   5650 C CE2 . TRP B 1 269 ? -31.66300 -22.52600 -32.34500 1.000 40.37600  ? 269 TRP B CE2 1 
ATOM   5651 C CE3 . TRP B 1 269 ? -29.35100 -23.16300 -32.04500 1.000 38.47100  ? 269 TRP B CE3 1 
ATOM   5652 C CZ2 . TRP B 1 269 ? -31.30600 -21.36900 -33.03300 1.000 43.09616  ? 269 TRP B CZ2 1 
ATOM   5653 C CZ3 . TRP B 1 269 ? -28.99700 -22.00700 -32.72200 1.000 39.30853  ? 269 TRP B CZ3 1 
ATOM   5654 C CH2 . TRP B 1 269 ? -29.97300 -21.13000 -33.21800 1.000 39.05900  ? 269 TRP B CH2 1 
ATOM   5655 N N   . GLY B 1 270 ? -28.44600 -26.96900 -32.14700 1.000 33.86248  ? 270 GLY B N   1 
ATOM   5656 C CA  . GLY B 1 270 ? -27.42200 -26.67900 -33.13100 1.000 29.95570  ? 270 GLY B CA  1 
ATOM   5657 C C   . GLY B 1 270 ? -26.05600 -26.86000 -32.51800 1.000 34.37022  ? 270 GLY B C   1 
ATOM   5658 O O   . GLY B 1 270 ? -25.91200 -27.51700 -31.47900 1.000 34.14276  ? 270 GLY B O   1 
ATOM   5659 N N   . LEU B 1 271 ? -25.05600 -26.24600 -33.15200 1.000 26.04984  ? 271 LEU B N   1 
ATOM   5660 C CA  . LEU B 1 271 ? -23.67500 -26.37100 -32.71400 1.000 30.97362  ? 271 LEU B CA  1 
ATOM   5661 C C   . LEU B 1 271 ? -22.95500 -25.04000 -32.83400 1.000 34.34938  ? 271 LEU B C   1 
ATOM   5662 O O   . LEU B 1 271 ? -23.28300 -24.19900 -33.68200 1.000 29.24581  ? 271 LEU B O   1 
ATOM   5663 C CB  . LEU B 1 271 ? -22.89000 -27.40700 -33.53500 1.000 32.08615  ? 271 LEU B CB  1 
ATOM   5664 C CG  . LEU B 1 271 ? -23.26800 -28.88100 -33.42200 1.000 29.19594  ? 271 LEU B CG  1 
ATOM   5665 C CD1 . LEU B 1 271 ? -22.41900 -29.65200 -34.36100 1.000 26.77898  ? 271 LEU B CD1 1 
ATOM   5666 C CD2 . LEU B 1 271 ? -23.08100 -29.37800 -32.00500 1.000 36.86499  ? 271 LEU B CD2 1 
ATOM   5667 N N   . ILE B 1 272 ? -21.94200 -24.87400 -31.99000 1.000 34.30297  ? 272 ILE B N   1 
ATOM   5668 C CA  . ILE B 1 272 ? -20.92400 -23.84900 -32.19200 1.000 30.34933  ? 272 ILE B CA  1 
ATOM   5669 C C   . ILE B 1 272 ? -19.67600 -24.57600 -32.67400 1.000 30.65397  ? 272 ILE B C   1 
ATOM   5670 O O   . ILE B 1 272 ? -19.08500 -25.37900 -31.94000 1.000 31.93914  ? 272 ILE B O   1 
ATOM   5671 C CB  . ILE B 1 272 ? -20.68900 -23.01900 -30.92500 1.000 28.03641  ? 272 ILE B CB  1 
ATOM   5672 C CG1 . ILE B 1 272 ? -21.89400 -22.08200 -30.73100 1.000 33.67127  ? 272 ILE B CG1 1 
ATOM   5673 C CG2 . ILE B 1 272 ? -19.38400 -22.21800 -31.02500 1.000 31.17199  ? 272 ILE B CG2 1 
ATOM   5674 C CD1 . ILE B 1 272 ? -21.70600 -20.97400 -29.69100 1.000 35.72542  ? 272 ILE B CD1 1 
ATOM   5675 N N   . ALA B 1 273 ? -19.31900 -24.34900 -33.93600 1.000 33.57746  ? 273 ALA B N   1 
ATOM   5676 C CA  . ALA B 1 273 ? -18.24700 -25.06700 -34.61300 1.000 34.79171  ? 273 ALA B CA  1 
ATOM   5677 C C   . ALA B 1 273 ? -17.05300 -24.14700 -34.76000 1.000 32.59262  ? 273 ALA B C   1 
ATOM   5678 O O   . ALA B 1 273 ? -17.21000 -22.99600 -35.18300 1.000 32.49273  ? 273 ALA B O   1 
ATOM   5679 C CB  . ALA B 1 273 ? -18.69800 -25.56300 -35.99100 1.000 29.86206  ? 273 ALA B CB  1 
ATOM   5680 N N   . CYS B 1 274 ? -15.86600 -24.64500 -34.40700 1.000 33.47879  ? 274 CYS B N   1 
ATOM   5681 C CA  . CYS B 1 274 ? -14.65600 -23.82900 -34.42200 1.000 32.77535  ? 274 CYS B CA  1 
ATOM   5682 C C   . CYS B 1 274 ? -13.58700 -24.51500 -35.26700 1.000 34.79472  ? 274 CYS B C   1 
ATOM   5683 O O   . CYS B 1 274 ? -13.35600 -25.71800 -35.12300 1.000 31.08339  ? 274 CYS B O   1 
ATOM   5684 C CB  . CYS B 1 274 ? -14.15200 -23.57100 -32.99900 1.000 31.39170  ? 274 CYS B CB  1 
ATOM   5685 S SG  . CYS B 1 274 ? -15.39000 -22.88200 -31.87000 1.000 34.61676  ? 274 CYS B SG  1 
ATOM   5686 N N   . HIS B 1 275 ? -12.96000 -23.75600 -36.16500 1.000 35.34772  ? 275 HIS B N   1 
ATOM   5687 C CA  . HIS B 1 275 ? -11.96400 -24.28600 -37.08500 1.000 34.55595  ? 275 HIS B CA  1 
ATOM   5688 C C   . HIS B 1 275 ? -10.65600 -23.54500 -36.90300 1.000 34.48328  ? 275 HIS B C   1 
ATOM   5689 O O   . HIS B 1 275 ? -10.64400 -22.33800 -36.62900 1.000 41.77492  ? 275 HIS B O   1 
ATOM   5690 C CB  . HIS B 1 275 ? -12.39700 -24.16900 -38.55200 1.000 35.80574  ? 275 HIS B CB  1 
ATOM   5691 C CG  . HIS B 1 275 ? -13.51000 -25.09700 -38.92600 1.000 39.54383  ? 275 HIS B CG  1 
ATOM   5692 N ND1 . HIS B 1 275 ? -14.20800 -24.98300 -40.11100 1.000 35.98297  ? 275 HIS B ND1 1 
ATOM   5693 C CD2 . HIS B 1 275 ? -14.05000 -26.15200 -38.26800 1.000 37.68363  ? 275 HIS B CD2 1 
ATOM   5694 C CE1 . HIS B 1 275 ? -15.12600 -25.93400 -40.16800 1.000 39.99673  ? 275 HIS B CE1 1 
ATOM   5695 N NE2 . HIS B 1 275 ? -15.05500 -26.65400 -39.06000 1.000 39.18602  ? 275 HIS B NE2 1 
ATOM   5696 N N   . HIS B 1 276 ? -9.56300  -24.28900 -37.04700 1.000 33.27835  ? 276 HIS B N   1 
ATOM   5697 C CA  . HIS B 1 276 ? -8.21200  -23.75100 -36.96900 1.000 34.92775  ? 276 HIS B CA  1 
ATOM   5698 C C   . HIS B 1 276 ? -7.39200  -24.42800 -38.05200 1.000 34.98268  ? 276 HIS B C   1 
ATOM   5699 O O   . HIS B 1 276 ? -7.36300  -25.66100 -38.11100 1.000 37.83520  ? 276 HIS B O   1 
ATOM   5700 C CB  . HIS B 1 276 ? -7.60100  -24.00100 -35.58800 1.000 35.78611  ? 276 HIS B CB  1 
ATOM   5701 C CG  . HIS B 1 276 ? -6.61300  -22.96100 -35.16900 1.000 37.42986  ? 276 HIS B CG  1 
ATOM   5702 N ND1 . HIS B 1 276 ? -6.95400  -21.63400 -34.99800 1.000 37.42474  ? 276 HIS B ND1 1 
ATOM   5703 C CD2 . HIS B 1 276 ? -5.29300  -23.05100 -34.88200 1.000 37.41177  ? 276 HIS B CD2 1 
ATOM   5704 C CE1 . HIS B 1 276 ? -5.88500  -20.95200 -34.62900 1.000 40.42522  ? 276 HIS B CE1 1 
ATOM   5705 N NE2 . HIS B 1 276 ? -4.86500  -21.78900 -34.54800 1.000 41.20192  ? 276 HIS B NE2 1 
ATOM   5706 N N   . LEU B 1 277 ? -6.75200  -23.62800 -38.91200 1.000 34.65229  ? 277 LEU B N   1 
ATOM   5707 C CA  . LEU B 1 277 ? -5.92300  -24.15700 -39.99100 1.000 38.81836  ? 277 LEU B CA  1 
ATOM   5708 C C   . LEU B 1 277 ? -4.74700  -24.96900 -39.47800 1.000 38.50750  ? 277 LEU B C   1 
ATOM   5709 O O   . LEU B 1 277 ? -4.23000  -25.81800 -40.21200 1.000 38.18373  ? 277 LEU B O   1 
ATOM   5710 C CB  . LEU B 1 277 ? -5.37800  -23.02100 -40.86800 1.000 42.62885  ? 277 LEU B CB  1 
ATOM   5711 C CG  . LEU B 1 277 ? -6.31500  -21.96600 -41.46400 1.000 41.56328  ? 277 LEU B CG  1 
ATOM   5712 C CD1 . LEU B 1 277 ? -5.50300  -20.81100 -42.04400 1.000 43.40864  ? 277 LEU B CD1 1 
ATOM   5713 C CD2 . LEU B 1 277 ? -7.21200  -22.55500 -42.52300 1.000 41.09305  ? 277 LEU B CD2 1 
ATOM   5714 N N   . GLU B 1 278 ? -4.30200  -24.71700 -38.25400 1.000 38.39990  ? 278 GLU B N   1 
ATOM   5715 C CA  . GLU B 1 278 ? -3.18700  -25.43800 -37.67800 1.000 41.19091  ? 278 GLU B CA  1 
ATOM   5716 C C   . GLU B 1 278 ? -3.62600  -26.21900 -36.45500 1.000 39.56818  ? 278 GLU B C   1 
ATOM   5717 O O   . GLU B 1 278 ? -4.58500  -25.82900 -35.78300 1.000 41.43306  ? 278 GLU B O   1 
ATOM   5718 C CB  . GLU B 1 278 ? -2.08200  -24.48300 -37.25000 1.000 42.86909  ? 278 GLU B CB  1 
ATOM   5719 C CG  . GLU B 1 278 ? -1.78400  -23.42600 -38.23800 1.000 50.56335  ? 278 GLU B CG  1 
ATOM   5720 C CD  . GLU B 1 278 ? -0.32500  -23.07400 -38.19800 1.000 64.32503  ? 278 GLU B CD  1 
ATOM   5721 O OE1 . GLU B 1 278 ? 0.06400   -22.34900 -37.25000 1.000 61.14620  ? 278 GLU B OE1 1 
ATOM   5722 O OE2 . GLU B 1 278 ? 0.42600   -23.55900 -39.08600 1.000 64.60044  ? 278 GLU B OE2 1 
ATOM   5723 N N   . PRO B 1 279 ? -2.92300  -27.30000 -36.11600 1.000 41.41812  ? 279 PRO B N   1 
ATOM   5724 C CA  . PRO B 1 279 ? -3.22700  -28.00300 -34.86800 1.000 38.53162  ? 279 PRO B CA  1 
ATOM   5725 C C   . PRO B 1 279 ? -3.20400  -27.03400 -33.70300 1.000 39.18533  ? 279 PRO B C   1 
ATOM   5726 O O   . PRO B 1 279 ? -2.45900  -26.04900 -33.70300 1.000 36.54082  ? 279 PRO B O   1 
ATOM   5727 C CB  . PRO B 1 279 ? -2.11200  -29.04500 -34.76700 1.000 32.03490  ? 279 PRO B CB  1 
ATOM   5728 C CG  . PRO B 1 279 ? -1.76000  -29.32200 -36.16800 1.000 37.55964  ? 279 PRO B CG  1 
ATOM   5729 C CD  . PRO B 1 279 ? -1.88300  -27.99600 -36.88900 1.000 41.85305  ? 279 PRO B CD  1 
ATOM   5730 N N   . LEU B 1 280 ? -4.05600  -27.31000 -32.71800 1.000 37.47118  ? 280 LEU B N   1 
ATOM   5731 C CA  . LEU B 1 280 ? -4.23400  -26.38600 -31.60500 1.000 34.70687  ? 280 LEU B CA  1 
ATOM   5732 C C   . LEU B 1 280 ? -4.92100  -27.12700 -30.47600 1.000 34.18253  ? 280 LEU B C   1 
ATOM   5733 O O   . LEU B 1 280 ? -6.04500  -27.60800 -30.64600 1.000 32.94299  ? 280 LEU B O   1 
ATOM   5734 C CB  . LEU B 1 280 ? -5.06300  -25.17700 -32.04300 1.000 36.68207  ? 280 LEU B CB  1 
ATOM   5735 C CG  . LEU B 1 280 ? -5.50100  -24.17900 -30.97600 1.000 38.29982  ? 280 LEU B CG  1 
ATOM   5736 C CD1 . LEU B 1 280 ? -4.30400  -23.58100 -30.29800 1.000 31.23585  ? 280 LEU B CD1 1 
ATOM   5737 C CD2 . LEU B 1 280 ? -6.33000  -23.08700 -31.61600 1.000 37.13597  ? 280 LEU B CD2 1 
ATOM   5738 N N   . HIS B 1 281 ? -4.26000  -27.20800 -29.32700 1.000 39.20360  ? 281 HIS B N   1 
ATOM   5739 C CA  . HIS B 1 281 ? -4.89200  -27.72800 -28.12700 1.000 33.45296  ? 281 HIS B CA  1 
ATOM   5740 C C   . HIS B 1 281 ? -5.51200  -26.60200 -27.32000 1.000 34.25239  ? 281 HIS B C   1 
ATOM   5741 O O   . HIS B 1 281 ? -4.91100  -25.53800 -27.15300 1.000 39.62740  ? 281 HIS B O   1 
ATOM   5742 C CB  . HIS B 1 281 ? -3.89500  -28.47000 -27.25600 1.000 31.76561  ? 281 HIS B CB  1 
ATOM   5743 C CG  . HIS B 1 281 ? -4.52600  -29.14700 -26.08500 1.000 34.35349  ? 281 HIS B CG  1 
ATOM   5744 N ND1 . HIS B 1 281 ? -4.43000  -28.65800 -24.79700 1.000 34.69622  ? 281 HIS B ND1 1 
ATOM   5745 C CD2 . HIS B 1 281 ? -5.28000  -30.26600 -26.01200 1.000 27.89388  ? 281 HIS B CD2 1 
ATOM   5746 C CE1 . HIS B 1 281 ? -5.08300  -29.46300 -23.97700 1.000 33.15067  ? 281 HIS B CE1 1 
ATOM   5747 N NE2 . HIS B 1 281 ? -5.62100  -30.43800 -24.69200 1.000 32.83726  ? 281 HIS B NE2 1 
ATOM   5748 N N   . ILE B 1 282 ? -6.71400  -26.85600 -26.81400 1.000 34.51324  ? 282 ILE B N   1 
ATOM   5749 C CA  . ILE B 1 282 ? -7.43200  -25.96500 -25.91400 1.000 32.96721  ? 282 ILE B CA  1 
ATOM   5750 C C   . ILE B 1 282 ? -7.62000  -26.71100 -24.59900 1.000 33.85923  ? 282 ILE B C   1 
ATOM   5751 O O   . ILE B 1 282 ? -8.15200  -27.82800 -24.59100 1.000 30.37520  ? 282 ILE B O   1 
ATOM   5752 C CB  . ILE B 1 282 ? -8.78800  -25.54600 -26.52000 1.000 38.44851  ? 282 ILE B CB  1 
ATOM   5753 C CG1 . ILE B 1 282 ? -8.57500  -24.56200 -27.66100 1.000 46.57874  ? 282 ILE B CG1 1 
ATOM   5754 C CG2 . ILE B 1 282 ? -9.66600  -24.88800 -25.49500 1.000 42.93498  ? 282 ILE B CG2 1 
ATOM   5755 C CD1 . ILE B 1 282 ? -7.92900  -23.24000 -27.21200 1.000 45.13282  ? 282 ILE B CD1 1 
ATOM   5756 N N   . SER B 1 283 ? -7.17400  -26.10900 -23.49300 1.000 35.02859  ? 283 SER B N   1 
ATOM   5757 C CA  . SER B 1 283 ? -7.21000  -26.78200 -22.19700 1.000 32.09124  ? 283 SER B CA  1 
ATOM   5758 C C   . SER B 1 283 ? -8.64100  -27.10600 -21.80100 1.000 29.97686  ? 283 SER B C   1 
ATOM   5759 O O   . SER B 1 283 ? -9.58400  -26.45800 -22.24100 1.000 32.79019  ? 283 SER B O   1 
ATOM   5760 C CB  . SER B 1 283 ? -6.59000  -25.91100 -21.10600 1.000 32.43110  ? 283 SER B CB  1 
ATOM   5761 O OG  . SER B 1 283 ? -7.48500  -24.86900 -20.70900 1.000 33.55342  ? 283 SER B OG  1 
ATOM   5762 N N   . HIS B 1 284 ? -8.78700  -28.11500 -20.93200 1.000 34.32080  ? 284 HIS B N   1 
ATOM   5763 C CA  . HIS B 1 284 ? -10.11300 -28.51800 -20.45900 1.000 35.45747  ? 284 HIS B CA  1 
ATOM   5764 C C   . HIS B 1 284 ? -10.74100 -27.42000 -19.62100 1.000 36.04593  ? 284 HIS B C   1 
ATOM   5765 O O   . HIS B 1 284 ? -11.95000 -27.16600 -19.70800 1.000 31.61832  ? 284 HIS B O   1 
ATOM   5766 C CB  . HIS B 1 284 ? -10.01700 -29.81700 -19.65000 1.000 32.51227  ? 284 HIS B CB  1 
ATOM   5767 C CG  . HIS B 1 284 ? -11.17900 -30.04700 -18.72500 1.000 39.61171  ? 284 HIS B CG  1 
ATOM   5768 N ND1 . HIS B 1 284 ? -12.32200 -30.72000 -19.11200 1.000 39.65595  ? 284 HIS B ND1 1 
ATOM   5769 C CD2 . HIS B 1 284 ? -11.37300 -29.69300 -17.42900 1.000 41.33990  ? 284 HIS B CD2 1 
ATOM   5770 C CE1 . HIS B 1 284 ? -13.16700 -30.77000 -18.09600 1.000 40.07967  ? 284 HIS B CE1 1 
ATOM   5771 N NE2 . HIS B 1 284 ? -12.61700 -30.15200 -17.06400 1.000 41.80056  ? 284 HIS B NE2 1 
ATOM   5772 N N   . GLU B 1 285 ? -9.92600  -26.76300 -18.79100 1.000 40.34479  ? 285 GLU B N   1 
ATOM   5773 C CA  . GLU B 1 285 ? -10.41800 -25.65400 -17.98900 1.000 37.17911  ? 285 GLU B CA  1 
ATOM   5774 C C   . GLU B 1 285 ? -11.01000 -24.56800 -18.87400 1.000 34.65695  ? 285 GLU B C   1 
ATOM   5775 O O   . GLU B 1 285 ? -12.02500 -23.95200 -18.52300 1.000 42.59670  ? 285 GLU B O   1 
ATOM   5776 C CB  . GLU B 1 285 ? -9.28000  -25.11600 -17.13000 1.000 40.44847  ? 285 GLU B CB  1 
ATOM   5777 C CG  . GLU B 1 285 ? -8.59500  -26.20600 -16.30900 1.000 41.73726  ? 285 GLU B CG  1 
ATOM   5778 C CD  . GLU B 1 285 ? -7.25000  -26.65800 -16.87500 1.000 38.25010  ? 285 GLU B CD  1 
ATOM   5779 O OE1 . GLU B 1 285 ? -7.20800  -27.19700 -17.99700 1.000 31.32643  ? 285 GLU B OE1 1 
ATOM   5780 O OE2 . GLU B 1 285 ? -6.22600  -26.46100 -16.18200 1.000 48.82103  ? 285 GLU B OE2 1 
ATOM   5781 N N   . ARG B 1 286 ? -10.40400 -24.34800 -20.04200 1.000 33.29176  ? 286 ARG B N   1 
ATOM   5782 C CA  . ARG B 1 286 ? -10.86400 -23.32800 -20.97500 1.000 34.62378  ? 286 ARG B CA  1 
ATOM   5783 C C   . ARG B 1 286 ? -12.00800 -23.83000 -21.85400 1.000 37.75956  ? 286 ARG B C   1 
ATOM   5784 O O   . ARG B 1 286 ? -12.86200 -23.03200 -22.27400 1.000 31.59147  ? 286 ARG B O   1 
ATOM   5785 C CB  . ARG B 1 286 ? -9.67400  -22.86600 -21.83000 1.000 35.77887  ? 286 ARG B CB  1 
ATOM   5786 C CG  . ARG B 1 286 ? -9.98100  -21.80100 -22.87600 1.000 37.67502  ? 286 ARG B CG  1 
ATOM   5787 C CD  . ARG B 1 286 ? -8.76300  -21.55100 -23.74400 1.000 34.72466  ? 286 ARG B CD  1 
ATOM   5788 N NE  . ARG B 1 286 ? -7.61900  -21.10800 -22.95300 1.000 40.39909  ? 286 ARG B NE  1 
ATOM   5789 C CZ  . ARG B 1 286 ? -7.24300  -19.83900 -22.85800 1.000 41.28571  ? 286 ARG B CZ  1 
ATOM   5790 N NH1 . ARG B 1 286 ? -7.89200  -18.88800 -23.49900 1.000 32.88625  ? 286 ARG B NH1 1 
ATOM   5791 N NH2 . ARG B 1 286 ? -6.19300  -19.51900 -22.09700 1.000 40.39906  ? 286 ARG B NH2 1 
ATOM   5792 N N   . ARG B 1 287 ? -12.02100 -25.13200 -22.17600 1.000 36.99052  ? 287 ARG B N   1 
ATOM   5793 C CA  . ARG B 1 287 ? -13.16800 -25.70900 -22.87400 1.000 31.91926  ? 287 ARG B CA  1 
ATOM   5794 C C   . ARG B 1 287 ? -14.41600 -25.59100 -22.02400 1.000 37.71496  ? 287 ARG B C   1 
ATOM   5795 O O   . ARG B 1 287 ? -15.51400 -25.34800 -22.54700 1.000 36.55920  ? 287 ARG B O   1 
ATOM   5796 C CB  . ARG B 1 287 ? -12.90800 -27.17800 -23.23300 1.000 33.47497  ? 287 ARG B CB  1 
ATOM   5797 C CG  . ARG B 1 287 ? -11.73400 -27.38500 -24.19500 1.000 33.17130  ? 287 ARG B CG  1 
ATOM   5798 C CD  . ARG B 1 287 ? -11.70900 -28.76500 -24.82400 1.000 31.91803  ? 287 ARG B CD  1 
ATOM   5799 N NE  . ARG B 1 287 ? -11.84500 -29.83500 -23.84800 1.000 28.75963  ? 287 ARG B NE  1 
ATOM   5800 C CZ  . ARG B 1 287 ? -10.84200 -30.60000 -23.42700 1.000 35.92205  ? 287 ARG B CZ  1 
ATOM   5801 N NH1 . ARG B 1 287 ? -9.60200  -30.43100 -23.87200 1.000 31.38171  ? 287 ARG B NH1 1 
ATOM   5802 N NH2 . ARG B 1 287 ? -11.08800 -31.56300 -22.54400 1.000 30.30885  ? 287 ARG B NH2 1 
ATOM   5803 N N   . ARG B 1 288 ? -14.25500 -25.73600 -20.70100 1.000 35.13901  ? 288 ARG B N   1 
ATOM   5804 C CA  . ARG B 1 288 ? -15.39300 -25.60900 -19.80600 1.000 32.08396  ? 288 ARG B CA  1 
ATOM   5805 C C   . ARG B 1 288 ? -15.84200 -24.15700 -19.68300 1.000 35.51477  ? 288 ARG B C   1 
ATOM   5806 O O   . ARG B 1 288 ? -17.04100 -23.88600 -19.56700 1.000 37.99530  ? 288 ARG B O   1 
ATOM   5807 C CB  . ARG B 1 288 ? -15.05200 -26.21400 -18.44800 1.000 37.74118  ? 288 ARG B CB  1 
ATOM   5808 C CG  . ARG B 1 288 ? -15.21600 -27.74100 -18.39900 1.000 43.36024  ? 288 ARG B CG  1 
ATOM   5809 C CD  . ARG B 1 288 ? -15.69400 -28.21100 -17.02000 1.000 50.07862  ? 288 ARG B CD  1 
ATOM   5810 N NE  . ARG B 1 288 ? -14.79000 -27.75400 -15.96700 1.000 57.75668  ? 288 ARG B NE  1 
ATOM   5811 C CZ  . ARG B 1 288 ? -15.17600 -27.28000 -14.78600 1.000 60.85950  ? 288 ARG B CZ  1 
ATOM   5812 N NH1 . ARG B 1 288 ? -16.46000 -27.21400 -14.45100 1.000 53.95788  ? 288 ARG B NH1 1 
ATOM   5813 N NH2 . ARG B 1 288 ? -14.25300 -26.84100 -13.93100 1.000 53.09199  ? 288 ARG B NH2 1 
ATOM   5814 N N   . ALA B 1 289 ? -14.90800 -23.20000 -19.72100 1.000 34.40221  ? 289 ALA B N   1 
ATOM   5815 C CA  . ALA B 1 289 ? -15.32600 -21.79800 -19.78600 1.000 32.83225  ? 289 ALA B CA  1 
ATOM   5816 C C   . ALA B 1 289 ? -16.17100 -21.53300 -21.03000 1.000 34.39673  ? 289 ALA B C   1 
ATOM   5817 O O   . ALA B 1 289 ? -17.18800 -20.83600 -20.96000 1.000 37.06111  ? 289 ALA B O   1 
ATOM   5818 C CB  . ALA B 1 289 ? -14.11200 -20.87400 -19.75900 1.000 26.23029  ? 289 ALA B CB  1 
ATOM   5819 N N   . CYS B 1 290 ? -15.78200 -22.10400 -22.17300 1.000 31.21689  ? 290 CYS B N   1 
ATOM   5820 C CA  . CYS B 1 290 ? -16.59100 -21.95100 -23.37900 1.000 37.29085  ? 290 CYS B CA  1 
ATOM   5821 C C   . CYS B 1 290 ? -17.96100 -22.59900 -23.22800 1.000 36.42420  ? 290 CYS B C   1 
ATOM   5822 O O   . CYS B 1 290 ? -18.95700 -22.07900 -23.74000 1.000 40.44611  ? 290 CYS B O   1 
ATOM   5823 C CB  . CYS B 1 290 ? -15.86000 -22.53600 -24.58100 1.000 32.36972  ? 290 CYS B CB  1 
ATOM   5824 S SG  . CYS B 1 290 ? -14.40900 -21.58000 -25.01200 1.000 42.16568  ? 290 CYS B SG  1 
ATOM   5825 N N   . GLU B 1 291 ? -18.03600 -23.74100 -22.54500 1.000 35.13418  ? 291 GLU B N   1 
ATOM   5826 C CA  . GLU B 1 291 ? -19.33500 -24.37700 -22.33900 1.000 37.94136  ? 291 GLU B CA  1 
ATOM   5827 C C   . GLU B 1 291 ? -20.31100 -23.44900 -21.62000 1.000 40.11997  ? 291 GLU B C   1 
ATOM   5828 O O   . GLU B 1 291 ? -21.52700 -23.52800 -21.83800 1.000 36.53715  ? 291 GLU B O   1 
ATOM   5829 C CB  . GLU B 1 291 ? -19.15700 -25.66800 -21.55500 1.000 34.88772  ? 291 GLU B CB  1 
ATOM   5830 C CG  . GLU B 1 291 ? -20.44200 -26.43300 -21.34200 1.000 44.96154  ? 291 GLU B CG  1 
ATOM   5831 C CD  . GLU B 1 291 ? -20.21900 -27.73800 -20.61400 1.000 49.27158  ? 291 GLU B CD  1 
ATOM   5832 O OE1 . GLU B 1 291 ? -19.19100 -27.84600 -19.91000 1.000 50.77715  ? 291 GLU B OE1 1 
ATOM   5833 O OE2 . GLU B 1 291 ? -21.06300 -28.65500 -20.75400 1.000 51.38477  ? 291 GLU B OE2 1 
ATOM   5834 N N   . VAL B 1 292 ? -19.79800 -22.56800 -20.75600 1.000 41.66757  ? 292 VAL B N   1 
ATOM   5835 C CA  . VAL B 1 292 ? -20.65900 -21.63700 -20.03100 1.000 39.03119  ? 292 VAL B CA  1 
ATOM   5836 C C   . VAL B 1 292 ? -21.29100 -20.64800 -20.99400 1.000 37.71318  ? 292 VAL B C   1 
ATOM   5837 O O   . VAL B 1 292 ? -22.48300 -20.33700 -20.89200 1.000 37.23754  ? 292 VAL B O   1 
ATOM   5838 C CB  . VAL B 1 292 ? -19.85900 -20.91000 -18.93300 1.000 41.34351  ? 292 VAL B CB  1 
ATOM   5839 C CG1 . VAL B 1 292 ? -20.76500 -19.94600 -18.16400 1.000 40.34775  ? 292 VAL B CG1 1 
ATOM   5840 C CG2 . VAL B 1 292 ? -19.18900 -21.91200 -17.99300 1.000 37.49535  ? 292 VAL B CG2 1 
ATOM   5841 N N   . LEU B 1 293 ? -20.49700 -20.13600 -21.94200 1.000 38.09850  ? 293 LEU B N   1 
ATOM   5842 C CA  . LEU B 1 293 ? -21.02000 -19.24500 -22.96900 1.000 36.64662  ? 293 LEU B CA  1 
ATOM   5843 C C   . LEU B 1 293 ? -22.16700 -19.89200 -23.74400 1.000 40.31987  ? 293 LEU B C   1 
ATOM   5844 O O   . LEU B 1 293 ? -23.18000 -19.23900 -24.01800 1.000 39.22732  ? 293 LEU B O   1 
ATOM   5845 C CB  . LEU B 1 293 ? -19.89900 -18.83100 -23.92200 1.000 34.28794  ? 293 LEU B CB  1 
ATOM   5846 C CG  . LEU B 1 293 ? -18.71900 -18.08800 -23.30300 1.000 35.52125  ? 293 LEU B CG  1 
ATOM   5847 C CD1 . LEU B 1 293 ? -17.57500 -17.96600 -24.29600 1.000 32.24110  ? 293 LEU B CD1 1 
ATOM   5848 C CD2 . LEU B 1 293 ? -19.15400 -16.71400 -22.77000 1.000 33.69534  ? 293 LEU B CD2 1 
ATOM   5849 N N   . THR B 1 294 ? -22.03400 -21.17400 -24.11100 1.000 39.41893  ? 294 THR B N   1 
ATOM   5850 C CA  . THR B 1 294 ? -23.07700 -21.78900 -24.92700 1.000 35.16942  ? 294 THR B CA  1 
ATOM   5851 C C   . THR B 1 294 ? -24.34200 -22.02300 -24.11400 1.000 39.62266  ? 294 THR B C   1 
ATOM   5852 O O   . THR B 1 294 ? -25.44900 -21.82000 -24.61800 1.000 41.83696  ? 294 THR B O   1 
ATOM   5853 C CB  . THR B 1 294 ? -22.58800 -23.09500 -25.54900 1.000 37.30284  ? 294 THR B CB  1 
ATOM   5854 O OG1 . THR B 1 294 ? -22.71700 -24.15900 -24.59700 1.000 46.77905  ? 294 THR B OG1 1 
ATOM   5855 C CG2 . THR B 1 294 ? -21.12200 -22.98100 -25.97100 1.000 41.18066  ? 294 THR B CG2 1 
ATOM   5856 N N   . GLN B 1 295 ? -24.21100 -22.43700 -22.85200 1.000 35.27287  ? 295 GLN B N   1 
ATOM   5857 C CA  . GLN B 1 295 ? -25.39700 -22.50500 -22.00800 1.000 39.14303  ? 295 GLN B CA  1 
ATOM   5858 C C   . GLN B 1 295 ? -26.02900 -21.13200 -21.80800 1.000 40.85957  ? 295 GLN B C   1 
ATOM   5859 O O   . GLN B 1 295 ? -27.24500 -21.02600 -21.63300 1.000 45.37617  ? 295 GLN B O   1 
ATOM   5860 C CB  . GLN B 1 295 ? -25.05500 -23.11300 -20.65900 1.000 42.15529  ? 295 GLN B CB  1 
ATOM   5861 C CG  . GLN B 1 295 ? -24.56000 -24.52900 -20.73000 1.000 45.71270  ? 295 GLN B CG  1 
ATOM   5862 C CD  . GLN B 1 295 ? -24.32000 -25.09000 -19.35500 1.000 52.47539  ? 295 GLN B CD  1 
ATOM   5863 O OE1 . GLN B 1 295 ? -24.97700 -24.69500 -18.39700 1.000 63.94058  ? 295 GLN B OE1 1 
ATOM   5864 N NE2 . GLN B 1 295 ? -23.36700 -26.00000 -19.24000 1.000 56.88800  ? 295 GLN B NE2 1 
ATOM   5865 N N   . LEU B 1 296 ? -25.23100 -20.06900 -21.82900 1.000 44.16174  ? 296 LEU B N   1 
ATOM   5866 C CA  . LEU B 1 296 ? -25.79200 -18.73400 -21.65500 1.000 45.67828  ? 296 LEU B CA  1 
ATOM   5867 C C   . LEU B 1 296 ? -26.51800 -18.26600 -22.91400 1.000 44.20847  ? 296 LEU B C   1 
ATOM   5868 O O   . LEU B 1 296 ? -27.55300 -17.59300 -22.83100 1.000 44.82038  ? 296 LEU B O   1 
ATOM   5869 C CB  . LEU B 1 296 ? -24.69000 -17.75100 -21.28300 1.000 46.05202  ? 296 LEU B CB  1 
ATOM   5870 C CG  . LEU B 1 296 ? -25.17600 -16.51700 -20.53500 1.000 53.60896  ? 296 LEU B CG  1 
ATOM   5871 C CD1 . LEU B 1 296 ? -25.42500 -16.88000 -19.08400 1.000 49.20221  ? 296 LEU B CD1 1 
ATOM   5872 C CD2 . LEU B 1 296 ? -24.14400 -15.41500 -20.66400 1.000 55.09977  ? 296 LEU B CD2 1 
ATOM   5873 N N   . LEU B 1 297 ? -25.98300 -18.59100 -24.08600 1.000 40.82201  ? 297 LEU B N   1 
ATOM   5874 C CA  . LEU B 1 297 ? -26.68500 -18.24900 -25.31100 1.000 40.55701  ? 297 LEU B CA  1 
ATOM   5875 C C   . LEU B 1 297 ? -27.99000 -19.02800 -25.42700 1.000 44.58097  ? 297 LEU B C   1 
ATOM   5876 O O   . LEU B 1 297 ? -29.01400 -18.48000 -25.85800 1.000 40.98939  ? 297 LEU B O   1 
ATOM   5877 C CB  . LEU B 1 297 ? -25.78500 -18.50400 -26.51600 1.000 41.47693  ? 297 LEU B CB  1 
ATOM   5878 C CG  . LEU B 1 297 ? -26.47700 -18.35900 -27.87600 1.000 39.51111  ? 297 LEU B CG  1 
ATOM   5879 C CD1 . LEU B 1 297 ? -26.85500 -16.91900 -28.18300 1.000 41.16873  ? 297 LEU B CD1 1 
ATOM   5880 C CD2 . LEU B 1 297 ? -25.59500 -18.93000 -28.96100 1.000 40.12724  ? 297 LEU B CD2 1 
ATOM   5881 N N   . ALA B 1 298 ? -27.98300 -20.30400 -25.03300 1.000 43.22490  ? 298 ALA B N   1 
ATOM   5882 C CA  . ALA B 1 298 ? -29.21700 -21.08300 -25.06400 1.000 40.53835  ? 298 ALA B CA  1 
ATOM   5883 C C   . ALA B 1 298 ? -30.28200 -20.44000 -24.19000 1.000 43.33089  ? 298 ALA B C   1 
ATOM   5884 O O   . ALA B 1 298 ? -31.46900 -20.44400 -24.53100 1.000 43.20768  ? 298 ALA B O   1 
ATOM   5885 C CB  . ALA B 1 298 ? -28.94700 -22.51500 -24.61300 1.000 39.51746  ? 298 ALA B CB  1 
ATOM   5886 N N   . LEU B 1 299 ? -29.86700 -19.86600 -23.06500 1.000 42.78788  ? 299 LEU B N   1 
ATOM   5887 C CA  . LEU B 1 299 ? -30.79800 -19.17700 -22.18500 1.000 40.66732  ? 299 LEU B CA  1 
ATOM   5888 C C   . LEU B 1 299 ? -31.30000 -17.87800 -22.81500 1.000 40.78174  ? 299 LEU B C   1 
ATOM   5889 O O   . LEU B 1 299 ? -32.49900 -17.57500 -22.75500 1.000 39.69082  ? 299 LEU B O   1 
ATOM   5890 C CB  . LEU B 1 299 ? -30.10300 -18.92500 -20.84400 1.000 44.57222  ? 299 LEU B CB  1 
ATOM   5891 C CG  . LEU B 1 299 ? -30.76000 -18.08700 -19.74700 1.000 44.25904  ? 299 LEU B CG  1 
ATOM   5892 C CD1 . LEU B 1 299 ? -32.13000 -18.61800 -19.39400 1.000 43.79608  ? 299 LEU B CD1 1 
ATOM   5893 C CD2 . LEU B 1 299 ? -29.86400 -18.05200 -18.53200 1.000 42.10879  ? 299 LEU B CD2 1 
ATOM   5894 N N   . GLN B 1 300 ? -30.39800 -17.10400 -23.43100 1.000 40.39339  ? 300 GLN B N   1 
ATOM   5895 C CA  . GLN B 1 300 ? -30.79000 -15.84800 -24.07400 1.000 47.03017  ? 300 GLN B CA  1 
ATOM   5896 C C   . GLN B 1 300 ? -31.73800 -16.07000 -25.25400 1.000 46.63321  ? 300 GLN B C   1 
ATOM   5897 O O   . GLN B 1 300 ? -32.58000 -15.20900 -25.55100 1.000 44.37426  ? 300 GLN B O   1 
ATOM   5898 C CB  . GLN B 1 300 ? -29.54600 -15.09200 -24.55300 1.000 45.55778  ? 300 GLN B CB  1 
ATOM   5899 C CG  . GLN B 1 300 ? -28.63800 -14.60400 -23.45200 1.000 45.06097  ? 300 GLN B CG  1 
ATOM   5900 C CD  . GLN B 1 300 ? -28.82800 -13.12400 -23.16900 1.000 58.14779  ? 300 GLN B CD  1 
ATOM   5901 O OE1 . GLN B 1 300 ? -29.95000 -12.60300 -23.20800 1.000 52.41299  ? 300 GLN B OE1 1 
ATOM   5902 N NE2 . GLN B 1 300 ? -27.72600 -12.43400 -22.89300 1.000 60.07565  ? 300 GLN B NE2 1 
ATOM   5903 N N   . LEU B 1 301 ? -31.60300 -17.19800 -25.95200 1.000 42.77378  ? 301 LEU B N   1 
ATOM   5904 C CA  . LEU B 1 301 ? -32.45300 -17.45200 -27.10600 1.000 39.64129  ? 301 LEU B CA  1 
ATOM   5905 C C   . LEU B 1 301 ? -33.83300 -17.93500 -26.68400 1.000 42.87226  ? 301 LEU B C   1 
ATOM   5906 O O   . LEU B 1 301 ? -34.83500 -17.58300 -27.32300 1.000 41.37679  ? 301 LEU B O   1 
ATOM   5907 C CB  . LEU B 1 301 ? -31.78800 -18.46600 -28.03400 1.000 40.09528  ? 301 LEU B CB  1 
ATOM   5908 C CG  . LEU B 1 301 ? -30.53800 -17.98400 -28.77000 1.000 44.53646  ? 301 LEU B CG  1 
ATOM   5909 C CD1 . LEU B 1 301 ? -29.81800 -19.17300 -29.38000 1.000 43.35206  ? 301 LEU B CD1 1 
ATOM   5910 C CD2 . LEU B 1 301 ? -30.89500 -16.95200 -29.85300 1.000 42.56699  ? 301 LEU B CD2 1 
ATOM   5911 N N   . SER B 1 302 ? -33.91200 -18.74000 -25.62200 1.000 38.97983  ? 302 SER B N   1 
ATOM   5912 C CA  . SER B 1 302 ? -35.22800 -19.13000 -25.11700 1.000 48.26429  ? 302 SER B CA  1 
ATOM   5913 C C   . SER B 1 302 ? -36.03100 -17.90500 -24.69900 1.000 46.51877  ? 302 SER B C   1 
ATOM   5914 O O   . SER B 1 302 ? -37.18500 -17.73600 -25.10700 1.000 49.50232  ? 302 SER B O   1 
ATOM   5915 C CB  . SER B 1 302 ? -35.09100 -20.11200 -23.95100 1.000 45.77606  ? 302 SER B CB  1 
ATOM   5916 O OG  . SER B 1 302 ? -34.98800 -21.44200 -24.43100 1.000 52.48809  ? 302 SER B OG  1 
ATOM   5917 N N   . ALA B 1 303 ? -35.42000 -17.01500 -23.91400 1.000 40.42080  ? 303 ALA B N   1 
ATOM   5918 C CA  . ALA B 1 303 ? -36.16300 -15.88600 -23.37300 1.000 42.24621  ? 303 ALA B CA  1 
ATOM   5919 C C   . ALA B 1 303 ? -36.56700 -14.88300 -24.45200 1.000 43.27422  ? 303 ALA B C   1 
ATOM   5920 O O   . ALA B 1 303 ? -37.58600 -14.20100 -24.30100 1.000 47.47503  ? 303 ALA B O   1 
ATOM   5921 C CB  . ALA B 1 303 ? -35.33700 -15.20300 -22.28400 1.000 41.75673  ? 303 ALA B CB  1 
ATOM   5922 N N   . GLU B 1 304 ? -35.78500 -14.75400 -25.52800 1.000 38.96915  ? 304 GLU B N   1 
ATOM   5923 C CA  . GLU B 1 304 ? -36.16700 -13.85800 -26.61400 1.000 37.42477  ? 304 GLU B CA  1 
ATOM   5924 C C   . GLU B 1 304 ? -37.20800 -14.50200 -27.50700 1.000 42.46064  ? 304 GLU B C   1 
ATOM   5925 O O   . GLU B 1 304 ? -38.14200 -13.83200 -27.95900 1.000 38.09174  ? 304 GLU B O   1 
ATOM   5926 C CB  . GLU B 1 304 ? -34.95200 -13.46400 -27.44900 1.000 45.44976  ? 304 GLU B CB  1 
ATOM   5927 C CG  . GLU B 1 304 ? -34.13000 -12.31800 -26.86700 1.000 56.94878  ? 304 GLU B CG  1 
ATOM   5928 C CD  . GLU B 1 304 ? -34.84100 -10.97700 -26.95400 1.000 58.32463  ? 304 GLU B CD  1 
ATOM   5929 O OE1 . GLU B 1 304 ? -35.48100 -10.70000 -28.00000 1.000 54.59158  ? 304 GLU B OE1 1 
ATOM   5930 O OE2 . GLU B 1 304 ? -34.75800 -10.20100 -25.97400 1.000 62.61459  ? 304 GLU B OE2 1 
ATOM   5931 N N   . GLU B 1 305 ? -37.05500 -15.79700 -27.78000 1.000 36.16159  ? 305 GLU B N   1 
ATOM   5932 C CA  . GLU B 1 305 ? -38.06900 -16.50700 -28.54500 1.000 41.42733  ? 305 GLU B CA  1 
ATOM   5933 C C   . GLU B 1 305 ? -39.41200 -16.45900 -27.82900 1.000 44.57650  ? 305 GLU B C   1 
ATOM   5934 O O   . GLU B 1 305 ? -40.44100 -16.12100 -28.42900 1.000 41.74942  ? 305 GLU B O   1 
ATOM   5935 C CB  . GLU B 1 305 ? -37.62600 -17.95000 -28.79000 1.000 45.17495  ? 305 GLU B CB  1 
ATOM   5936 C CG  . GLU B 1 305 ? -38.68800 -18.83600 -29.42500 1.000 60.59078  ? 305 GLU B CG  1 
ATOM   5937 C CD  . GLU B 1 305 ? -38.09100 -20.03800 -30.14700 1.000 65.41916  ? 305 GLU B CD  1 
ATOM   5938 O OE1 . GLU B 1 305 ? -37.09300 -20.58900 -29.63800 1.000 57.92830  ? 305 GLU B OE1 1 
ATOM   5939 O OE2 . GLU B 1 305 ? -38.61000 -20.41900 -31.22600 1.000 67.54681  ? 305 GLU B OE2 1 
ATOM   5940 N N   . ARG B 1 306 ? -39.41800 -16.75900 -26.52900 1.000 41.23198  ? 306 ARG B N   1 
ATOM   5941 C CA  . ARG B 1 306 ? -40.67300 -16.71400 -25.79000 1.000 44.84957  ? 306 ARG B CA  1 
ATOM   5942 C C   . ARG B 1 306 ? -41.23800 -15.29900 -25.74000 1.000 42.40042  ? 306 ARG B C   1 
ATOM   5943 O O   . ARG B 1 306 ? -42.46100 -15.12600 -25.76300 1.000 38.90576  ? 306 ARG B O   1 
ATOM   5944 C CB  . ARG B 1 306 ? -40.48200 -17.29300 -24.38200 1.000 47.84866  ? 306 ARG B CB  1 
ATOM   5945 C CG  . ARG B 1 306 ? -40.02300 -18.76300 -24.37800 1.000 47.87192  ? 306 ARG B CG  1 
ATOM   5946 C CD  . ARG B 1 306 ? -40.69100 -19.58800 -23.27800 1.000 53.19972  ? 306 ARG B CD  1 
ATOM   5947 N NE  . ARG B 1 306 ? -39.96100 -20.81600 -22.96400 1.000 59.70757  ? 306 ARG B NE  1 
ATOM   5948 C CZ  . ARG B 1 306 ? -38.94600 -20.89500 -22.10700 1.000 63.42818  ? 306 ARG B CZ  1 
ATOM   5949 N NH1 . ARG B 1 306 ? -38.46700 -19.82500 -21.49300 1.000 54.93978  ? 306 ARG B NH1 1 
ATOM   5950 N NH2 . ARG B 1 306 ? -38.39900 -22.08200 -21.85100 1.000 69.32507  ? 306 ARG B NH2 1 
ATOM   5951 N N   . ALA B 1 307 ? -40.37400 -14.27300 -25.70200 1.000 41.07595  ? 307 ALA B N   1 
ATOM   5952 C CA  . ALA B 1 307 ? -40.87500 -12.89900 -25.73100 1.000 39.40126  ? 307 ALA B CA  1 
ATOM   5953 C C   . ALA B 1 307 ? -41.43500 -12.54100 -27.10100 1.000 40.97388  ? 307 ALA B C   1 
ATOM   5954 O O   . ALA B 1 307 ? -42.41800 -11.80200 -27.20400 1.000 38.65981  ? 307 ALA B O   1 
ATOM   5955 C CB  . ALA B 1 307 ? -39.77700 -11.91600 -25.33300 1.000 42.39667  ? 307 ALA B CB  1 
ATOM   5956 N N   . ALA B 1 308 ? -40.82200 -13.05000 -28.16500 1.000 40.29201  ? 308 ALA B N   1 
ATOM   5957 C CA  . ALA B 1 308 ? -41.33800 -12.79200 -29.49900 1.000 38.60921  ? 308 ALA B CA  1 
ATOM   5958 C C   . ALA B 1 308 ? -42.71400 -13.41500 -29.68000 1.000 38.15159  ? 308 ALA B C   1 
ATOM   5959 O O   . ALA B 1 308 ? -43.62600 -12.77700 -30.21600 1.000 38.95230  ? 308 ALA B O   1 
ATOM   5960 C CB  . ALA B 1 308 ? -40.36400 -13.32600 -30.54400 1.000 42.35932  ? 308 ALA B CB  1 
ATOM   5961 N N   . GLU B 1 309 ? -42.88300 -14.65800 -29.22700 1.000 40.44933  ? 309 GLU B N   1 
ATOM   5962 C CA  . GLU B 1 309 ? -44.14800 -15.36100 -29.41400 1.000 41.09497  ? 309 GLU B CA  1 
ATOM   5963 C C   . GLU B 1 309 ? -45.27100 -14.75600 -28.57600 1.000 38.23954  ? 309 GLU B C   1 
ATOM   5964 O O   . GLU B 1 309 ? -46.43500 -14.77600 -28.99700 1.000 37.31831  ? 309 GLU B O   1 
ATOM   5965 C CB  . GLU B 1 309 ? -43.96400 -16.83800 -29.09100 1.000 47.21476  ? 309 GLU B CB  1 
ATOM   5966 C CG  . GLU B 1 309 ? -42.85600 -17.48600 -29.89400 1.000 52.65282  ? 309 GLU B CG  1 
ATOM   5967 C CD  . GLU B 1 309 ? -43.04200 -18.98300 -30.04400 1.000 61.48233  ? 309 GLU B CD  1 
ATOM   5968 O OE1 . GLU B 1 309 ? -43.89100 -19.38800 -30.86800 1.000 59.49105  ? 309 GLU B OE1 1 
ATOM   5969 O OE2 . GLU B 1 309 ? -42.34300 -19.75000 -29.33700 1.000 63.92516  ? 309 GLU B OE2 1 
ATOM   5970 N N   . ALA B 1 310 ? -44.94900 -14.20500 -27.40600 1.000 37.53539  ? 310 ALA B N   1 
ATOM   5971 C CA  . ALA B 1 310 ? -45.93200 -13.42900 -26.65500 1.000 34.97720  ? 310 ALA B CA  1 
ATOM   5972 C C   . ALA B 1 310 ? -46.36700 -12.17800 -27.42200 1.000 39.34105  ? 310 ALA B C   1 
ATOM   5973 O O   . ALA B 1 310 ? -47.56700 -11.91500 -27.57700 1.000 41.85063  ? 310 ALA B O   1 
ATOM   5974 C CB  . ALA B 1 310 ? -45.35600 -13.05400 -25.29300 1.000 36.54308  ? 310 ALA B CB  1 
ATOM   5975 N N   . SER B 1 311 ? -45.40200 -11.38000 -27.89900 1.000 35.48873  ? 311 SER B N   1 
ATOM   5976 C CA  . SER B 1 311 ? -45.73800 -10.22400 -28.72700 1.000 37.28150  ? 311 SER B CA  1 
ATOM   5977 C C   . SER B 1 311 ? -46.57500 -10.62600 -29.93900 1.000 39.21370  ? 311 SER B C   1 
ATOM   5978 O O   . SER B 1 311 ? -47.48100 -9.88700  -30.35100 1.000 36.71442  ? 311 SER B O   1 
ATOM   5979 C CB  . SER B 1 311 ? -44.46700 -9.51300  -29.18000 1.000 32.59982  ? 311 SER B CB  1 
ATOM   5980 O OG  . SER B 1 311 ? -43.80600 -8.93700  -28.07600 1.000 37.28534  ? 311 SER B OG  1 
ATOM   5981 N N   . GLU B 1 312 ? -46.27700 -11.79000 -30.52900 1.000 36.16353  ? 312 GLU B N   1 
ATOM   5982 C CA  . GLU B 1 312 ? -47.08400 -12.29400 -31.63600 1.000 35.83493  ? 312 GLU B CA  1 
ATOM   5983 C C   . GLU B 1 312 ? -48.52800 -12.50600 -31.20900 1.000 38.43219  ? 312 GLU B C   1 
ATOM   5984 O O   . GLU B 1 312 ? -49.45700 -12.01700 -31.85700 1.000 37.68623  ? 312 GLU B O   1 
ATOM   5985 C CB  . GLU B 1 312 ? -46.51200 -13.60900 -32.16900 1.000 38.65134  ? 312 GLU B CB  1 
ATOM   5986 C CG  . GLU B 1 312 ? -45.61100 -13.46100 -33.37900 1.000 45.79432  ? 312 GLU B CG  1 
ATOM   5987 C CD  . GLU B 1 312 ? -46.10700 -12.42600 -34.36700 1.000 49.03074  ? 312 GLU B CD  1 
ATOM   5988 O OE1 . GLU B 1 312 ? -47.30400 -12.46300 -34.76300 1.000 49.44243  ? 312 GLU B OE1 1 
ATOM   5989 O OE2 . GLU B 1 312 ? -45.28600 -11.56400 -34.73700 1.000 39.72685  ? 312 GLU B OE2 1 
ATOM   5990 N N   . ASP B 1 313 ? -48.73700 -13.26400 -30.13400 1.000 35.85004  ? 313 ASP B N   1 
ATOM   5991 C CA  . ASP B 1 313 ? -50.09500 -13.52000 -29.67700 1.000 35.00851  ? 313 ASP B CA  1 
ATOM   5992 C C   . ASP B 1 313 ? -50.82700 -12.22100 -29.36900 1.000 39.36071  ? 313 ASP B C   1 
ATOM   5993 O O   . ASP B 1 313 ? -52.01400 -12.07800 -29.69500 1.000 41.94274  ? 313 ASP B O   1 
ATOM   5994 C CB  . ASP B 1 313 ? -50.06500 -14.41900 -28.45100 1.000 40.47840  ? 313 ASP B CB  1 
ATOM   5995 C CG  . ASP B 1 313 ? -49.76000 -15.85300 -28.78800 1.000 47.24608  ? 313 ASP B CG  1 
ATOM   5996 O OD1 . ASP B 1 313 ? -49.46900 -16.16700 -29.97500 1.000 44.56035  ? 313 ASP B OD1 1 
ATOM   5997 O OD2 . ASP B 1 313 ? -49.83300 -16.67400 -27.84900 1.000 54.72906  ? 313 ASP B OD2 1 
ATOM   5998 N N   . ALA B 1 314 ? -50.12800 -11.25600 -28.75400 1.000 35.14870  ? 314 ALA B N   1 
ATOM   5999 C CA  . ALA B 1 314 ? -50.74300 -9.96200  -28.45500 1.000 38.29564  ? 314 ALA B CA  1 
ATOM   6000 C C   . ALA B 1 314 ? -51.25900 -9.27900  -29.71500 1.000 36.22686  ? 314 ALA B C   1 
ATOM   6001 O O   . ALA B 1 314 ? -52.36200 -8.72500  -29.70900 1.000 33.14556  ? 314 ALA B O   1 
ATOM   6002 C CB  . ALA B 1 314 ? -49.75900 -9.03900  -27.73100 1.000 28.45180  ? 314 ALA B CB  1 
ATOM   6003 N N   . HIS B 1 315 ? -50.47600 -9.29200  -30.80400 1.000 36.14852  ? 315 HIS B N   1 
ATOM   6004 C CA  . HIS B 1 315 ? -50.95800 -8.69800  -32.04800 1.000 33.14386  ? 315 HIS B CA  1 
ATOM   6005 C C   . HIS B 1 315 ? -52.16600 -9.45700  -32.59500 1.000 38.72773  ? 315 HIS B C   1 
ATOM   6006 O O   . HIS B 1 315 ? -53.18000 -8.84700  -32.95300 1.000 34.73467  ? 315 HIS B O   1 
ATOM   6007 C CB  . HIS B 1 315 ? -49.84800 -8.63300  -33.09100 1.000 34.01014  ? 315 HIS B CB  1 
ATOM   6008 C CG  . HIS B 1 315 ? -50.32200 -8.12800  -34.42000 1.000 48.57356  ? 315 HIS B CG  1 
ATOM   6009 N ND1 . HIS B 1 315 ? -50.91800 -6.89400  -34.57800 1.000 53.97075  ? 315 HIS B ND1 1 
ATOM   6010 C CD2 . HIS B 1 315 ? -50.32800 -8.70700  -35.64700 1.000 53.82899  ? 315 HIS B CD2 1 
ATOM   6011 C CE1 . HIS B 1 315 ? -51.24300 -6.72200  -35.84900 1.000 56.63805  ? 315 HIS B CE1 1 
ATOM   6012 N NE2 . HIS B 1 315 ? -50.89600 -7.80700  -36.52000 1.000 57.21607  ? 315 HIS B NE2 1 
ATOM   6013 N N   . ARG B 1 316 ? -52.08400 -10.79500 -32.65900 1.000 39.85384  ? 316 ARG B N   1 
ATOM   6014 C CA  . ARG B 1 316 ? -53.20300 -11.57600 -33.18600 1.000 37.38640  ? 316 ARG B CA  1 
ATOM   6015 C C   . ARG B 1 316 ? -54.45600 -11.34900 -32.35500 1.000 40.61642  ? 316 ARG B C   1 
ATOM   6016 O O   . ARG B 1 316 ? -55.55000 -11.14100 -32.89900 1.000 39.37862  ? 316 ARG B O   1 
ATOM   6017 C CB  . ARG B 1 316 ? -52.86200 -13.06400 -33.22000 1.000 36.11502  ? 316 ARG B CB  1 
ATOM   6018 C CG  . ARG B 1 316 ? -51.61700 -13.42900 -34.00600 1.000 39.19607  ? 316 ARG B CG  1 
ATOM   6019 C CD  . ARG B 1 316 ? -51.63600 -12.91100 -35.43600 1.000 35.82469  ? 316 ARG B CD  1 
ATOM   6020 N NE  . ARG B 1 316 ? -50.30800 -13.04600 -36.02000 1.000 46.20288  ? 316 ARG B NE  1 
ATOM   6021 C CZ  . ARG B 1 316 ? -49.92100 -14.03400 -36.81900 1.000 44.48447  ? 316 ARG B CZ  1 
ATOM   6022 N NH1 . ARG B 1 316 ? -50.77300 -14.94400 -37.26900 1.000 39.00579  ? 316 ARG B NH1 1 
ATOM   6023 N NH2 . ARG B 1 316 ? -48.64400 -14.10800 -37.17900 1.000 48.10693  ? 316 ARG B NH2 1 
ATOM   6024 N N   . ALA B 1 317 ? -54.30700 -11.36600 -31.02700 1.000 37.76223  ? 317 ALA B N   1 
ATOM   6025 C CA  . ALA B 1 317 ? -55.45700 -11.22900 -30.14100 1.000 38.54515  ? 317 ALA B CA  1 
ATOM   6026 C C   . ALA B 1 317 ? -56.07300 -9.84400  -30.23100 1.000 36.43170  ? 317 ALA B C   1 
ATOM   6027 O O   . ALA B 1 317 ? -57.28700 -9.70700  -30.09700 1.000 37.91521  ? 317 ALA B O   1 
ATOM   6028 C CB  . ALA B 1 317 ? -55.05900 -11.55200 -28.69700 1.000 36.16830  ? 317 ALA B CB  1 
ATOM   6029 N N   . ALA B 1 318 ? -55.26900 -8.80800  -30.46800 1.000 33.63874  ? 318 ALA B N   1 
ATOM   6030 C CA  . ALA B 1 318 ? -55.86000 -7.51100  -30.76100 1.000 38.52131  ? 318 ALA B CA  1 
ATOM   6031 C C   . ALA B 1 318 ? -56.69900 -7.56600  -32.04800 1.000 44.55931  ? 318 ALA B C   1 
ATOM   6032 O O   . ALA B 1 318 ? -57.81900 -7.04200  -32.08500 1.000 46.45152  ? 318 ALA B O   1 
ATOM   6033 C CB  . ALA B 1 318 ? -54.76200 -6.45400  -30.83300 1.000 28.48255  ? 318 ALA B CB  1 
ATOM   6034 N N   . LEU B 1 319 ? -56.19300 -8.23000  -33.09900 1.000 39.54282  ? 319 LEU B N   1 
ATOM   6035 C CA  . LEU B 1 319 ? -56.97300 -8.41800  -34.32400 1.000 40.57752  ? 319 LEU B CA  1 
ATOM   6036 C C   . LEU B 1 319 ? -58.29000 -9.13300  -34.04200 1.000 47.21507  ? 319 LEU B C   1 
ATOM   6037 O O   . LEU B 1 319 ? -59.35600 -8.68400  -34.47400 1.000 50.17244  ? 319 LEU B O   1 
ATOM   6038 C CB  . LEU B 1 319 ? -56.17100 -9.21200  -35.35000 1.000 46.56607  ? 319 LEU B CB  1 
ATOM   6039 C CG  . LEU B 1 319 ? -55.13200 -8.48400  -36.19600 1.000 45.76378  ? 319 LEU B CG  1 
ATOM   6040 C CD1 . LEU B 1 319 ? -54.65300 -9.40500  -37.31300 1.000 42.48247  ? 319 LEU B CD1 1 
ATOM   6041 C CD2 . LEU B 1 319 ? -55.74900 -7.22800  -36.75500 1.000 52.24927  ? 319 LEU B CD2 1 
ATOM   6042 N N   . LEU B 1 320 ? -58.22600 -10.26200 -33.32900 1.000 47.01354  ? 320 LEU B N   1 
ATOM   6043 C CA  . LEU B 1 320 ? -59.42900 -11.00700 -32.97000 1.000 45.22753  ? 320 LEU B CA  1 
ATOM   6044 C C   . LEU B 1 320 ? -60.43200 -10.13400 -32.23100 1.000 45.33709  ? 320 LEU B C   1 
ATOM   6045 O O   . LEU B 1 320 ? -61.63700 -10.19700 -32.50300 1.000 50.53218  ? 320 LEU B O   1 
ATOM   6046 C CB  . LEU B 1 320 ? -59.04800 -12.21600 -32.11500 1.000 40.58857  ? 320 LEU B CB  1 
ATOM   6047 C CG  . LEU B 1 320 ? -59.00800 -13.49700 -32.93800 1.000 32.93974  ? 320 LEU B CG  1 
ATOM   6048 C CD1 . LEU B 1 320 ? -58.46800 -14.62200 -32.13500 1.000 24.61322  ? 320 LEU B CD1 1 
ATOM   6049 C CD2 . LEU B 1 320 ? -60.41000 -13.80600 -33.43700 1.000 36.97572  ? 320 LEU B CD2 1 
ATOM   6050 N N   . GLY B 1 321 ? -59.95500 -9.32500  -31.28200 1.000 45.58759  ? 321 GLY B N   1 
ATOM   6051 C CA  . GLY B 1 321 ? -60.84500 -8.43100  -30.55800 1.000 48.71698  ? 321 GLY B CA  1 
ATOM   6052 C C   . GLY B 1 321 ? -61.45000 -7.34500  -31.43300 1.000 51.40366  ? 321 GLY B C   1 
ATOM   6053 O O   . GLY B 1 321 ? -62.60000 -6.94700  -31.22900 1.000 50.76674  ? 321 GLY B O   1 
ATOM   6054 N N   . GLN B 1 322 ? -60.68300 -6.83700  -32.40700 1.000 49.24191  ? 322 GLN B N   1 
ATOM   6055 C CA  . GLN B 1 322 ? -61.24400 -5.88000  -33.35900 1.000 48.36904  ? 322 GLN B CA  1 
ATOM   6056 C C   . GLN B 1 322 ? -62.30100 -6.53600  -34.24100 1.000 48.74754  ? 322 GLN B C   1 
ATOM   6057 O O   . GLN B 1 322 ? -63.27000 -5.88100  -34.63800 1.000 55.25614  ? 322 GLN B O   1 
ATOM   6058 C CB  . GLN B 1 322 ? -60.12500 -5.26000  -34.20800 1.000 51.94122  ? 322 GLN B CB  1 
ATOM   6059 C CG  . GLN B 1 322 ? -59.17700 -4.34100  -33.39800 1.000 56.50368  ? 322 GLN B CG  1 
ATOM   6060 C CD  . GLN B 1 322 ? -57.80800 -4.09300  -34.05300 1.000 56.98786  ? 322 GLN B CD  1 
ATOM   6061 O OE1 . GLN B 1 322 ? -57.64500 -4.18000  -35.27900 1.000 60.24427  ? 322 GLN B OE1 1 
ATOM   6062 N NE2 . GLN B 1 322 ? -56.81600 -3.78300  -33.22100 1.000 54.11427  ? 322 GLN B NE2 1 
ATOM   6063 N N   . LEU B 1 323 ? -62.14100 -7.82700  -34.53700 1.000 48.65953  ? 323 LEU B N   1 
ATOM   6064 C CA  . LEU B 1 323 ? -63.16700 -8.57400  -35.25900 1.000 56.42566  ? 323 LEU B CA  1 
ATOM   6065 C C   . LEU B 1 323 ? -64.41700 -8.76300  -34.41200 1.000 56.55250  ? 323 LEU B C   1 
ATOM   6066 O O   . LEU B 1 323 ? -65.54000 -8.68400  -34.92100 1.000 58.34911  ? 323 LEU B O   1 
ATOM   6067 C CB  . LEU B 1 323 ? -62.61400 -9.93100  -35.69200 1.000 51.06188  ? 323 LEU B CB  1 
ATOM   6068 C CG  . LEU B 1 323 ? -62.37900 -10.08000 -37.19700 1.000 59.51124  ? 323 LEU B CG  1 
ATOM   6069 C CD1 . LEU B 1 323 ? -61.60600 -8.88300  -37.73200 1.000 54.85150  ? 323 LEU B CD1 1 
ATOM   6070 C CD2 . LEU B 1 323 ? -61.65500 -11.38200 -37.51000 1.000 53.87253  ? 323 LEU B CD2 1 
ATOM   6071 N N   . ALA B 1 324 ? -64.24100 -9.03400  -33.12100 1.000 59.62907  ? 324 ALA B N   1 
ATOM   6072 C CA  . ALA B 1 324 ? -65.38900 -9.23500  -32.24800 1.000 56.83924  ? 324 ALA B CA  1 
ATOM   6073 C C   . ALA B 1 324 ? -66.21000 -7.96000  -32.13400 1.000 58.72599  ? 324 ALA B C   1 
ATOM   6074 O O   . ALA B 1 324 ? -67.42700 -7.97600  -32.35000 1.000 65.21591  ? 324 ALA B O   1 
ATOM   6075 C CB  . ALA B 1 324 ? -64.92400 -9.71200  -30.87300 1.000 54.70317  ? 324 ALA B CB  1 
ATOM   6076 N N   . THR B 1 325 ? -65.55800 -6.84100  -31.79400 1.000 54.17124  ? 325 THR B N   1 
ATOM   6077 C CA  . THR B 1 325 ? -66.23400 -5.54600  -31.79600 1.000 51.53617  ? 325 THR B CA  1 
ATOM   6078 C C   . THR B 1 325 ? -67.00100 -5.30500  -33.09900 1.000 64.98588  ? 325 THR B C   1 
ATOM   6079 O O   . THR B 1 325 ? -68.10300 -4.74500  -33.08000 1.000 68.09246  ? 325 THR B O   1 
ATOM   6080 C CB  . THR B 1 325 ? -65.22200 -4.41500  -31.57400 1.000 52.89644  ? 325 THR B CB  1 
ATOM   6081 O OG1 . THR B 1 325 ? -64.62400 -4.52700  -30.27800 1.000 47.84572  ? 325 THR B OG1 1 
ATOM   6082 C CG2 . THR B 1 325 ? -65.89700 -3.07100  -31.68500 1.000 55.29073  ? 325 THR B CG2 1 
ATOM   6083 N N   . ALA B 1 326 ? -66.45200 -5.73700  -34.23800 1.000 62.06207  ? 326 ALA B N   1 
ATOM   6084 C CA  . ALA B 1 326 ? -67.11800 -5.47700  -35.51100 1.000 62.63995  ? 326 ALA B CA  1 
ATOM   6085 C C   . ALA B 1 326 ? -68.41900 -6.25900  -35.62000 1.000 64.62413  ? 326 ALA B C   1 
ATOM   6086 O O   . ALA B 1 326 ? -69.48300 -5.68400  -35.87500 1.000 68.31937  ? 326 ALA B O   1 
ATOM   6087 C CB  . ALA B 1 326 ? -66.18800 -5.82000  -36.67100 1.000 66.61038  ? 326 ALA B CB  1 
ATOM   6088 N N   . MET B 1 327 ? -68.35100 -7.57600  -35.43100 1.000 64.87696  ? 327 MET B N   1 
ATOM   6089 C CA  . MET B 1 327 ? -69.55800 -8.39200  -35.48800 1.000 70.04553  ? 327 MET B CA  1 
ATOM   6090 C C   . MET B 1 327 ? -70.58500 -7.93200  -34.46300 1.000 72.52544  ? 327 MET B C   1 
ATOM   6091 O O   . MET B 1 327 ? -71.79300 -7.94700  -34.72800 1.000 79.48000  ? 327 MET B O   1 
ATOM   6092 C CB  . MET B 1 327 ? -69.20200 -9.85800  -35.26400 1.000 65.87457  ? 327 MET B CB  1 
ATOM   6093 C CG  . MET B 1 327 ? -68.14200 -10.36900 -36.20900 1.000 70.95380  ? 327 MET B CG  1 
ATOM   6094 S SD  . MET B 1 327 ? -67.45700 -11.94900 -35.69500 1.000 67.32502  ? 327 MET B SD  1 
ATOM   6095 C CE  . MET B 1 327 ? -68.47700 -12.31800 -34.25400 1.000 72.14612  ? 327 MET B CE  1 
ATOM   6096 N N   . GLY B 1 328 ? -70.12300 -7.51700  -33.28700 1.000 73.73227  ? 328 GLY B N   1 
ATOM   6097 C CA  . GLY B 1 328 ? -71.01400 -7.02200  -32.26200 1.000 77.71080  ? 328 GLY B CA  1 
ATOM   6098 C C   . GLY B 1 328 ? -71.39700 -5.58400  -32.52400 1.000 78.65369  ? 328 GLY B C   1 
ATOM   6099 O O   . GLY B 1 328 ? -71.40200 -4.75900  -31.60600 1.000 84.22304  ? 328 GLY B O   1 
ATOM   6100 N N   . GLU B 1 329 ? -71.70900 -5.26800  -33.78100 1.000 77.54585  ? 329 GLU B N   1 
ATOM   6101 C CA  . GLU B 1 329 ? -72.09300 -3.91300  -34.14100 1.000 81.95299  ? 329 GLU B CA  1 
ATOM   6102 C C   . GLU B 1 329 ? -73.14400 -3.92000  -35.24500 1.000 87.71003  ? 329 GLU B C   1 
ATOM   6103 O O   . GLU B 1 329 ? -73.25800 -2.95300  -36.00700 1.000 84.63521  ? 329 GLU B O   1 
ATOM   6104 C CB  . GLU B 1 329 ? -70.86900 -3.09500  -34.55700 1.000 74.74719  ? 329 GLU B CB  1 
ATOM   6105 C CG  . GLU B 1 329 ? -70.81200 -1.72000  -33.92800 1.000 77.39768  ? 329 GLU B CG  1 
ATOM   6106 C CD  . GLU B 1 329 ? -69.55900 -0.95900  -34.30900 1.000 83.06425  ? 329 GLU B CD  1 
ATOM   6107 O OE1 . GLU B 1 329 ? -68.46300 -1.34000  -33.84100 1.000 79.95391  ? 329 GLU B OE1 1 
ATOM   6108 O OE2 . GLU B 1 329 ? -69.66800 0.01700   -35.08500 1.000 85.44637  ? 329 GLU B OE2 1 
ATOM   6109 N N   . GLY B 1 330 ? -73.92300 -4.99700  -35.33500 1.000 86.00918  ? 330 GLY B N   1 
ATOM   6110 C CA  . GLY B 1 330 ? -74.98500 -5.09300  -36.31700 1.000 96.86139  ? 330 GLY B CA  1 
ATOM   6111 C C   . GLY B 1 330 ? -75.09000 -6.46200  -36.95700 1.000 100.45689 ? 330 GLY B C   1 
ATOM   6112 O O   . GLY B 1 330 ? -74.09900 -6.97100  -37.48800 1.000 100.79429 ? 330 GLY B O   1 
ATOM   6113 N N   . GLY B 1 331 ? -76.27900 -7.07300  -36.89700 1.000 103.95833 ? 331 GLY B N   1 
ATOM   6114 C CA  . GLY B 1 331 ? -76.53200 -8.35000  -37.54200 1.000 104.63592 ? 331 GLY B CA  1 
ATOM   6115 C C   . GLY B 1 331 ? -76.17500 -8.31400  -39.01400 1.000 109.46879 ? 331 GLY B C   1 
ATOM   6116 O O   . GLY B 1 331 ? -76.90500 -7.72700  -39.82000 1.000 112.16902 ? 331 GLY B O   1 
ATOM   6117 N N   . THR B 1 332 ? -75.05900 -8.95000  -39.38100 1.000 106.17579 ? 332 THR B N   1 
ATOM   6118 C CA  . THR B 1 332 ? -74.43500 -8.66400  -40.66600 1.000 101.16299 ? 332 THR B CA  1 
ATOM   6119 C C   . THR B 1 332 ? -73.27300 -9.60600  -40.99300 1.000 100.84622 ? 332 THR B C   1 
ATOM   6120 O O   . THR B 1 332 ? -72.10800 -9.22100  -40.84700 1.000 100.45474 ? 332 THR B O   1 
ATOM   6121 C CB  . THR B 1 332 ? -73.95800 -7.20800  -40.65400 1.000 98.37081  ? 332 THR B CB  1 
ATOM   6122 N N   . LEU B 1 333 ? -73.56700 -10.82200 -41.46800 1.000 96.16682  ? 333 LEU B N   1 
ATOM   6123 C CA  . LEU B 1 333 ? -72.55000 -11.86300 -41.63300 1.000 94.92924  ? 333 LEU B CA  1 
ATOM   6124 C C   . LEU B 1 333 ? -71.49900 -11.52600 -42.69200 1.000 95.19646  ? 333 LEU B C   1 
ATOM   6125 O O   . LEU B 1 333 ? -70.43400 -10.97900 -42.38600 1.000 89.33045  ? 333 LEU B O   1 
ATOM   6126 C CB  . LEU B 1 333 ? -73.20400 -13.20300 -42.00500 1.000 99.69666  ? 333 LEU B CB  1 
ATOM   6127 C CG  . LEU B 1 333 ? -74.53000 -13.66600 -41.38400 1.000 100.02452 ? 333 LEU B CG  1 
ATOM   6128 C CD1 . LEU B 1 333 ? -75.02700 -14.96800 -42.02900 1.000 91.58423  ? 333 LEU B CD1 1 
ATOM   6129 C CD2 . LEU B 1 333 ? -74.40600 -13.83200 -39.87800 1.000 98.77479  ? 333 LEU B CD2 1 
ATOM   6130 N N   . GLU B 1 334 ? -71.80100 -11.86000 -43.94800 1.000 92.32775  ? 334 GLU B N   1 
ATOM   6131 C CA  . GLU B 1 334 ? -70.83600 -11.80500 -45.03800 1.000 88.17374  ? 334 GLU B CA  1 
ATOM   6132 C C   . GLU B 1 334 ? -70.34800 -10.39600 -45.34500 1.000 89.21650  ? 334 GLU B C   1 
ATOM   6133 O O   . GLU B 1 334 ? -69.45200 -10.24300 -46.18500 1.000 88.85360  ? 334 GLU B O   1 
ATOM   6134 C CB  . GLU B 1 334 ? -71.44900 -12.41100 -46.30500 1.000 91.71129  ? 334 GLU B CB  1 
ATOM   6135 C CG  . GLU B 1 334 ? -72.00800 -13.82400 -46.14400 1.000 95.94840  ? 334 GLU B CG  1 
ATOM   6136 C CD  . GLU B 1 334 ? -73.36000 -13.86200 -45.44600 1.000 99.74648  ? 334 GLU B CD  1 
ATOM   6137 O OE1 . GLU B 1 334 ? -74.00600 -12.79800 -45.33500 1.000 98.44046  ? 334 GLU B OE1 1 
ATOM   6138 O OE2 . GLU B 1 334 ? -73.77200 -14.95500 -44.99800 1.000 102.21291 ? 334 GLU B OE2 1 
ATOM   6139 N N   . GLU B 1 335 ? -70.90800 -9.37000  -44.71100 1.000 90.75061  ? 335 GLU B N   1 
ATOM   6140 C CA  . GLU B 1 335 ? -70.49500 -8.00600  -45.00900 1.000 88.74067  ? 335 GLU B CA  1 
ATOM   6141 C C   . GLU B 1 335 ? -69.43500 -7.47900  -44.05800 1.000 84.88017  ? 335 GLU B C   1 
ATOM   6142 O O   . GLU B 1 335 ? -68.57300 -6.70400  -44.48700 1.000 82.59981  ? 335 GLU B O   1 
ATOM   6143 C CB  . GLU B 1 335 ? -71.70400 -7.06500  -45.00100 1.000 92.19162  ? 335 GLU B CB  1 
ATOM   6144 C CG  . GLU B 1 335 ? -72.48200 -7.03800  -43.70200 1.000 97.07922  ? 335 GLU B CG  1 
ATOM   6145 C CD  . GLU B 1 335 ? -73.88000 -7.64400  -43.82300 1.000 103.23743 ? 335 GLU B CD  1 
ATOM   6146 O OE1 . GLU B 1 335 ? -73.99000 -8.86800  -44.06700 1.000 98.34777  ? 335 GLU B OE1 1 
ATOM   6147 O OE2 . GLU B 1 335 ? -74.87200 -6.89700  -43.64400 1.000 102.25757 ? 335 GLU B OE2 1 
ATOM   6148 N N   . VAL B 1 336 ? -69.46400 -7.87800  -42.78300 1.000 83.42244  ? 336 VAL B N   1 
ATOM   6149 C CA  . VAL B 1 336 ? -68.39000 -7.46100  -41.88900 1.000 80.88262  ? 336 VAL B CA  1 
ATOM   6150 C C   . VAL B 1 336 ? -67.08800 -8.15300  -42.27400 1.000 78.99236  ? 336 VAL B C   1 
ATOM   6151 O O   . VAL B 1 336 ? -66.00700 -7.55300  -42.17600 1.000 74.89629  ? 336 VAL B O   1 
ATOM   6152 C CB  . VAL B 1 336 ? -68.77200 -7.71400  -40.41700 1.000 82.30284  ? 336 VAL B CB  1 
ATOM   6153 C CG1 . VAL B 1 336 ? -70.01700 -6.91100  -40.04400 1.000 83.02027  ? 336 VAL B CG1 1 
ATOM   6154 C CG2 . VAL B 1 336 ? -68.99600 -9.18400  -40.16300 1.000 87.69417  ? 336 VAL B CG2 1 
ATOM   6155 N N   . LEU B 1 337 ? -67.16300 -9.40900  -42.73400 1.000 77.09745  ? 337 LEU B N   1 
ATOM   6156 C CA  . LEU B 1 337 ? -65.98000 -10.04500 -43.30600 1.000 75.08113  ? 337 LEU B CA  1 
ATOM   6157 C C   . LEU B 1 337 ? -65.48600 -9.26100  -44.50900 1.000 71.45130  ? 337 LEU B C   1 
ATOM   6158 O O   . LEU B 1 337 ? -64.28100 -9.02500  -44.65700 1.000 71.13599  ? 337 LEU B O   1 
ATOM   6159 C CB  . LEU B 1 337 ? -66.27200 -11.49600 -43.70100 1.000 71.05007  ? 337 LEU B CB  1 
ATOM   6160 C CG  . LEU B 1 337 ? -66.44600 -12.55200 -42.60200 1.000 70.08853  ? 337 LEU B CG  1 
ATOM   6161 C CD1 . LEU B 1 337 ? -65.33400 -12.48900 -41.56000 1.000 59.88309  ? 337 LEU B CD1 1 
ATOM   6162 C CD2 . LEU B 1 337 ? -67.81200 -12.45700 -41.93800 1.000 75.97929  ? 337 LEU B CD2 1 
ATOM   6163 N N   . GLU B 1 338 ? -66.40700 -8.82700  -45.36900 1.000 72.87824  ? 338 GLU B N   1 
ATOM   6164 C CA  . GLU B 1 338 ? -66.02100 -7.96900  -46.48100 1.000 79.64081  ? 338 GLU B CA  1 
ATOM   6165 C C   . GLU B 1 338 ? -65.42400 -6.65900  -45.97700 1.000 73.61516  ? 338 GLU B C   1 
ATOM   6166 O O   . GLU B 1 338 ? -64.42800 -6.16900  -46.52000 1.000 69.31904  ? 338 GLU B O   1 
ATOM   6167 C CB  . GLU B 1 338 ? -67.22900 -7.70300  -47.38200 1.000 87.08912  ? 338 GLU B CB  1 
ATOM   6168 C CG  . GLU B 1 338 ? -67.51800 -8.78300  -48.42200 1.000 89.61986  ? 338 GLU B CG  1 
ATOM   6169 C CD  . GLU B 1 338 ? -66.93100 -8.45900  -49.79800 1.000 102.54773 ? 338 GLU B CD  1 
ATOM   6170 O OE1 . GLU B 1 338 ? -65.68800 -8.34100  -49.91000 1.000 99.72839  ? 338 GLU B OE1 1 
ATOM   6171 O OE2 . GLU B 1 338 ? -67.71500 -8.31400  -50.76600 1.000 103.11044 ? 338 GLU B OE2 1 
ATOM   6172 N N   . LYS B 1 339 ? -66.00600 -6.08400  -44.92900 1.000 71.84932  ? 339 LYS B N   1 
ATOM   6173 C CA  . LYS B 1 339 ? -65.51900 -4.79800  -44.45900 1.000 71.20454  ? 339 LYS B CA  1 
ATOM   6174 C C   . LYS B 1 339 ? -64.26700 -4.92400  -43.59800 1.000 73.93152  ? 339 LYS B C   1 
ATOM   6175 O O   . LYS B 1 339 ? -63.51200 -3.95100  -43.48900 1.000 76.31597  ? 339 LYS B O   1 
ATOM   6176 C CB  . LYS B 1 339 ? -66.62400 -4.06900  -43.69500 1.000 67.36667  ? 339 LYS B CB  1 
ATOM   6177 C CG  . LYS B 1 339 ? -66.42500 -2.57200  -43.66000 1.000 72.06187  ? 339 LYS B CG  1 
ATOM   6178 C CD  . LYS B 1 339 ? -67.42800 -1.90000  -42.72800 1.000 82.09771  ? 339 LYS B CD  1 
ATOM   6179 C CE  . LYS B 1 339 ? -66.97500 -0.49200  -42.32700 1.000 70.79592  ? 339 LYS B CE  1 
ATOM   6180 N NZ  . LYS B 1 339 ? -67.70100 0.58800   -43.05700 1.000 75.10165  ? 339 LYS B NZ  1 
ATOM   6181 N N   . GLU B 1 340 ? -64.01600 -6.09800  -43.00700 1.000 70.49997  ? 340 GLU B N   1 
ATOM   6182 C CA  . GLU B 1 340 ? -62.80100 -6.31700  -42.22300 1.000 72.68204  ? 340 GLU B CA  1 
ATOM   6183 C C   . GLU B 1 340 ? -61.83300 -7.27400  -42.92000 1.000 68.59897  ? 340 GLU B C   1 
ATOM   6184 O O   . GLU B 1 340 ? -61.28800 -8.19200  -42.29500 1.000 62.32827  ? 340 GLU B O   1 
ATOM   6185 C CB  . GLU B 1 340 ? -63.16100 -6.85600  -40.83700 1.000 71.48231  ? 340 GLU B CB  1 
ATOM   6186 C CG  . GLU B 1 340 ? -64.19100 -6.02900  -40.08500 1.000 74.90706  ? 340 GLU B CG  1 
ATOM   6187 C CD  . GLU B 1 340 ? -63.61800 -4.76100  -39.48600 1.000 75.02459  ? 340 GLU B CD  1 
ATOM   6188 O OE1 . GLU B 1 340 ? -62.44100 -4.42700  -39.76900 1.000 77.53143  ? 340 GLU B OE1 1 
ATOM   6189 O OE2 . GLU B 1 340 ? -64.35100 -4.09600  -38.72600 1.000 72.76093  ? 340 GLU B OE2 1 
ATOM   6190 N N   . SER B 1 341 ? -61.58200 -7.04300  -44.20800 1.000 63.51708  ? 341 SER B N   1 
ATOM   6191 C CA  . SER B 1 341 ? -60.88700 -8.03900  -45.01000 1.000 56.87432  ? 341 SER B CA  1 
ATOM   6192 C C   . SER B 1 341 ? -59.43500 -8.21000  -44.58400 1.000 58.79804  ? 341 SER B C   1 
ATOM   6193 O O   . SER B 1 341 ? -58.93500 -9.34100  -44.53300 1.000 59.16469  ? 341 SER B O   1 
ATOM   6194 C CB  . SER B 1 341 ? -60.97300 -7.66400  -46.48500 1.000 69.05803  ? 341 SER B CB  1 
ATOM   6195 O OG  . SER B 1 341 ? -62.31400 -7.75400  -46.93400 1.000 76.61765  ? 341 SER B OG  1 
ATOM   6196 N N   . GLU B 1 342 ? -58.72900 -7.11500  -44.28700 1.000 50.11427  ? 342 GLU B N   1 
ATOM   6197 C CA  . GLU B 1 342 ? -57.32200 -7.27800  -43.94200 1.000 54.98860  ? 342 GLU B CA  1 
ATOM   6198 C C   . GLU B 1 342 ? -57.17200 -8.00800  -42.61500 1.000 58.57476  ? 342 GLU B C   1 
ATOM   6199 O O   . GLU B 1 342 ? -56.31900 -8.89700  -42.48200 1.000 58.86404  ? 342 GLU B O   1 
ATOM   6200 C CB  . GLU B 1 342 ? -56.59700 -5.92800  -43.90000 1.000 63.36067  ? 342 GLU B CB  1 
ATOM   6201 C CG  . GLU B 1 342 ? -55.21600 -5.94800  -44.57300 1.000 69.54737  ? 342 GLU B CG  1 
ATOM   6202 C CD  . GLU B 1 342 ? -54.29300 -4.82800  -44.09900 1.000 75.39791  ? 342 GLU B CD  1 
ATOM   6203 O OE1 . GLU B 1 342 ? -54.52300 -3.65200  -44.47600 1.000 69.67720  ? 342 GLU B OE1 1 
ATOM   6204 O OE2 . GLU B 1 342 ? -53.33700 -5.13300  -43.34100 1.000 71.98109  ? 342 GLU B OE2 1 
ATOM   6205 N N   . ARG B 1 343 ? -58.01100 -7.66600  -41.63200 1.000 52.43084  ? 343 ARG B N   1 
ATOM   6206 C CA  . ARG B 1 343 ? -57.88800 -8.28200  -40.31700 1.000 50.37649  ? 343 ARG B CA  1 
ATOM   6207 C C   . ARG B 1 343 ? -58.15500 -9.77900  -40.37600 1.000 44.76082  ? 343 ARG B C   1 
ATOM   6208 O O   . ARG B 1 343 ? -57.49500 -10.55200 -39.67600 1.000 47.21519  ? 343 ARG B O   1 
ATOM   6209 C CB  . ARG B 1 343 ? -58.84200 -7.60600  -39.33600 1.000 59.38448  ? 343 ARG B CB  1 
ATOM   6210 C CG  . ARG B 1 343 ? -58.50000 -6.16400  -38.97800 1.000 59.49166  ? 343 ARG B CG  1 
ATOM   6211 C CD  . ARG B 1 343 ? -59.60700 -5.57000  -38.11700 1.000 63.00590  ? 343 ARG B CD  1 
ATOM   6212 N NE  . ARG B 1 343 ? -59.16300 -4.42500  -37.33100 1.000 65.78649  ? 343 ARG B NE  1 
ATOM   6213 C CZ  . ARG B 1 343 ? -59.33200 -3.16100  -37.69000 1.000 67.74167  ? 343 ARG B CZ  1 
ATOM   6214 N NH1 . ARG B 1 343 ? -59.93000 -2.84100  -38.82800 1.000 68.07512  ? 343 ARG B NH1 1 
ATOM   6215 N NH2 . ARG B 1 343 ? -58.89400 -2.19400  -36.88700 1.000 65.97100  ? 343 ARG B NH2 1 
ATOM   6216 N N   . VAL B 1 344 ? -59.13000 -10.20500 -41.18700 1.000 46.57577  ? 344 VAL B N   1 
ATOM   6217 C CA  . VAL B 1 344 ? -59.37700 -11.63700 -41.36500 1.000 49.78501  ? 344 VAL B CA  1 
ATOM   6218 C C   . VAL B 1 344 ? -58.18700 -12.30500 -42.05400 1.000 47.15771  ? 344 VAL B C   1 
ATOM   6219 O O   . VAL B 1 344 ? -57.88600 -13.47800 -41.80500 1.000 48.74455  ? 344 VAL B O   1 
ATOM   6220 C CB  . VAL B 1 344 ? -60.68500 -11.87100 -42.15500 1.000 51.04013  ? 344 VAL B CB  1 
ATOM   6221 C CG1 . VAL B 1 344 ? -60.95100 -13.35500 -42.34400 1.000 42.32230  ? 344 VAL B CG1 1 
ATOM   6222 C CG2 . VAL B 1 344 ? -61.86500 -11.21900 -41.46100 1.000 45.98015  ? 344 VAL B CG2 1 
ATOM   6223 N N   . LEU B 1 345 ? -57.49100 -11.58000 -42.91900 1.000 41.67411  ? 345 LEU B N   1 
ATOM   6224 C CA  . LEU B 1 345 ? -56.36000 -12.15100 -43.62600 1.000 40.37093  ? 345 LEU B CA  1 
ATOM   6225 C C   . LEU B 1 345 ? -55.08600 -12.10100 -42.79100 1.000 42.73064  ? 345 LEU B C   1 
ATOM   6226 O O   . LEU B 1 345 ? -54.34300 -13.08800 -42.73800 1.000 38.54308  ? 345 LEU B O   1 
ATOM   6227 C CB  . LEU B 1 345 ? -56.16200 -11.41400 -44.94700 1.000 38.91241  ? 345 LEU B CB  1 
ATOM   6228 C CG  . LEU B 1 345 ? -56.97700 -12.07300 -46.03900 1.000 41.91288  ? 345 LEU B CG  1 
ATOM   6229 C CD1 . LEU B 1 345 ? -57.09100 -11.20400 -47.26100 1.000 40.76113  ? 345 LEU B CD1 1 
ATOM   6230 C CD2 . LEU B 1 345 ? -56.27300 -13.35200 -46.35800 1.000 46.20095  ? 345 LEU B CD2 1 
ATOM   6231 N N   . ALA B 1 346 ? -54.83400 -10.97000 -42.12700 1.000 37.58567  ? 346 ALA B N   1 
ATOM   6232 C CA  . ALA B 1 346 ? -53.67500 -10.84000 -41.25900 1.000 40.84413  ? 346 ALA B CA  1 
ATOM   6233 C C   . ALA B 1 346 ? -53.78700 -11.71700 -40.01900 1.000 42.05845  ? 346 ALA B C   1 
ATOM   6234 O O   . ALA B 1 346 ? -52.77700 -11.95500 -39.35200 1.000 37.45953  ? 346 ALA B O   1 
ATOM   6235 C CB  . ALA B 1 346 ? -53.48700 -9.38100  -40.84800 1.000 39.21647  ? 346 ALA B CB  1 
ATOM   6236 N N   . LEU B 1 347 ? -54.98900 -12.19000 -39.69100 1.000 34.46917  ? 347 LEU B N   1 
ATOM   6237 C CA  . LEU B 1 347 ? -55.14200 -13.08800 -38.55500 1.000 40.52497  ? 347 LEU B CA  1 
ATOM   6238 C C   . LEU B 1 347 ? -54.11800 -14.21100 -38.60800 1.000 37.49083  ? 347 LEU B C   1 
ATOM   6239 O O   . LEU B 1 347 ? -53.48100 -14.53900 -37.60300 1.000 33.82618  ? 347 LEU B O   1 
ATOM   6240 C CB  . LEU B 1 347 ? -56.55800 -13.66400 -38.52700 1.000 42.27210  ? 347 LEU B CB  1 
ATOM   6241 C CG  . LEU B 1 347 ? -57.53300 -12.91700 -37.63700 1.000 45.20511  ? 347 LEU B CG  1 
ATOM   6242 C CD1 . LEU B 1 347 ? -58.84300 -13.66700 -37.59000 1.000 43.14649  ? 347 LEU B CD1 1 
ATOM   6243 C CD2 . LEU B 1 347 ? -56.92200 -12.75000 -36.23700 1.000 45.31932  ? 347 LEU B CD2 1 
ATOM   6244 N N   . THR B 1 348 ? -53.95800 -14.81300 -39.78500 1.000 40.72827  ? 348 THR B N   1 
ATOM   6245 C CA  . THR B 1 348 ? -53.02100 -15.90200 -40.01200 1.000 34.96415  ? 348 THR B CA  1 
ATOM   6246 C C   . THR B 1 348 ? -51.96300 -15.53900 -41.03600 1.000 31.84098  ? 348 THR B C   1 
ATOM   6247 O O   . THR B 1 348 ? -51.30300 -16.44200 -41.55600 1.000 34.20539  ? 348 THR B O   1 
ATOM   6248 C CB  . THR B 1 348 ? -53.75100 -17.15200 -40.50100 1.000 38.51173  ? 348 THR B CB  1 
ATOM   6249 O OG1 . THR B 1 348 ? -54.21300 -16.90600 -41.83600 1.000 31.56112  ? 348 THR B OG1 1 
ATOM   6250 C CG2 . THR B 1 348 ? -54.92200 -17.48000 -39.59700 1.000 33.12222  ? 348 THR B CG2 1 
ATOM   6251 N N   . GLY B 1 349 ? -51.80800 -14.25900 -41.36200 1.000 30.91732  ? 349 GLY B N   1 
ATOM   6252 C CA  . GLY B 1 349 ? -50.80500 -13.84300 -42.33500 1.000 34.46133  ? 349 GLY B CA  1 
ATOM   6253 C C   . GLY B 1 349 ? -51.03900 -14.36900 -43.73700 1.000 35.21126  ? 349 GLY B C   1 
ATOM   6254 O O   . GLY B 1 349 ? -50.08400 -14.76100 -44.42000 1.000 33.07048  ? 349 GLY B O   1 
ATOM   6255 N N   . ALA B 1 350 ? -52.29200 -14.38400 -44.18200 1.000 37.47208  ? 350 ALA B N   1 
ATOM   6256 C CA  . ALA B 1 350 ? -52.71100 -15.04300 -45.40900 1.000 33.25675  ? 350 ALA B CA  1 
ATOM   6257 C C   . ALA B 1 350 ? -52.95700 -14.01600 -46.50200 1.000 38.36847  ? 350 ALA B C   1 
ATOM   6258 O O   . ALA B 1 350 ? -52.98800 -12.80400 -46.26000 1.000 31.95548  ? 350 ALA B O   1 
ATOM   6259 C CB  . ALA B 1 350 ? -53.97900 -15.87700 -45.17700 1.000 33.20574  ? 350 ALA B CB  1 
ATOM   6260 N N   . ALA B 1 351 ? -53.13700 -14.52800 -47.72800 1.000 36.99646  ? 351 ALA B N   1 
ATOM   6261 C CA  . ALA B 1 351 ? -53.43100 -13.69500 -48.88500 1.000 42.23418  ? 351 ALA B CA  1 
ATOM   6262 C C   . ALA B 1 351 ? -54.86100 -13.82800 -49.38000 1.000 40.90072  ? 351 ALA B C   1 
ATOM   6263 O O   . ALA B 1 351 ? -55.32600 -12.94100 -50.09600 1.000 38.74522  ? 351 ALA B O   1 
ATOM   6264 C CB  . ALA B 1 351 ? -52.47900 -14.01800 -50.04600 1.000 34.32363  ? 351 ALA B CB  1 
ATOM   6265 N N   . GLY B 1 352 ? -55.55700 -14.91100 -49.03400 1.000 40.56678  ? 352 GLY B N   1 
ATOM   6266 C CA  . GLY B 1 352 ? -56.97600 -15.02200 -49.30100 1.000 41.78966  ? 352 GLY B CA  1 
ATOM   6267 C C   . GLY B 1 352 ? -57.62800 -15.88000 -48.24000 1.000 48.10286  ? 352 GLY B C   1 
ATOM   6268 O O   . GLY B 1 352 ? -56.95300 -16.50600 -47.41800 1.000 47.86020  ? 352 GLY B O   1 
ATOM   6269 N N   . VAL B 1 353 ? -58.95900 -15.89800 -48.25700 1.000 45.56172  ? 353 VAL B N   1 
ATOM   6270 C CA  . VAL B 1 353 ? -59.68500 -16.78000 -47.35400 1.000 43.67794  ? 353 VAL B CA  1 
ATOM   6271 C C   . VAL B 1 353 ? -61.04000 -17.15500 -47.95000 1.000 46.29997  ? 353 VAL B C   1 
ATOM   6272 O O   . VAL B 1 353 ? -61.85300 -16.29000 -48.30600 1.000 43.66402  ? 353 VAL B O   1 
ATOM   6273 C CB  . VAL B 1 353 ? -59.83300 -16.15400 -45.94900 1.000 44.79152  ? 353 VAL B CB  1 
ATOM   6274 C CG1 . VAL B 1 353 ? -60.48900 -14.79300 -46.01900 1.000 44.75561  ? 353 VAL B CG1 1 
ATOM   6275 C CG2 . VAL B 1 353 ? -60.62200 -17.06600 -45.02300 1.000 39.32154  ? 353 VAL B CG2 1 
ATOM   6276 N N   . ALA B 1 354 ? -61.27400 -18.45800 -48.07100 1.000 47.03124  ? 354 ALA B N   1 
ATOM   6277 C CA  . ALA B 1 354 ? -62.58300 -18.99900 -48.42100 1.000 51.13592  ? 354 ALA B CA  1 
ATOM   6278 C C   . ALA B 1 354 ? -63.35900 -19.29300 -47.14300 1.000 52.75789  ? 354 ALA B C   1 
ATOM   6279 O O   . ALA B 1 354 ? -62.87500 -20.02800 -46.27000 1.000 50.95103  ? 354 ALA B O   1 
ATOM   6280 C CB  . ALA B 1 354 ? -62.44100 -20.26900 -49.25400 1.000 47.27045  ? 354 ALA B CB  1 
ATOM   6281 N N   . LEU B 1 355 ? -64.55800 -18.71900 -47.03600 1.000 57.32320  ? 355 LEU B N   1 
ATOM   6282 C CA  . LEU B 1 355 ? -65.43700 -18.90200 -45.88400 1.000 63.34739  ? 355 LEU B CA  1 
ATOM   6283 C C   . LEU B 1 355 ? -66.63800 -19.74100 -46.30900 1.000 65.25792  ? 355 LEU B C   1 
ATOM   6284 O O   . LEU B 1 355 ? -67.50300 -19.26800 -47.05000 1.000 69.13160  ? 355 LEU B O   1 
ATOM   6285 C CB  . LEU B 1 355 ? -65.86900 -17.55300 -45.31300 1.000 62.18622  ? 355 LEU B CB  1 
ATOM   6286 C CG  . LEU B 1 355 ? -64.87400 -17.02100 -44.27800 1.000 60.69619  ? 355 LEU B CG  1 
ATOM   6287 C CD1 . LEU B 1 355 ? -65.13900 -15.58000 -43.87400 1.000 56.90905  ? 355 LEU B CD1 1 
ATOM   6288 C CD2 . LEU B 1 355 ? -64.93900 -17.92500 -43.06800 1.000 59.30549  ? 355 LEU B CD2 1 
ATOM   6289 N N   . LEU B 1 356 ? -66.67700 -20.99400 -45.85500 1.000 65.95923  ? 356 LEU B N   1 
ATOM   6290 C CA  . LEU B 1 356 ? -67.80600 -21.88800 -46.10800 1.000 75.11790  ? 356 LEU B CA  1 
ATOM   6291 C C   . LEU B 1 356 ? -68.73400 -21.87300 -44.89900 1.000 82.12329  ? 356 LEU B C   1 
ATOM   6292 O O   . LEU B 1 356 ? -68.73600 -22.77500 -44.05300 1.000 74.79984  ? 356 LEU B O   1 
ATOM   6293 C CB  . LEU B 1 356 ? -67.32700 -23.29100 -46.40900 1.000 71.93951  ? 356 LEU B CB  1 
ATOM   6294 C CG  . LEU B 1 356 ? -67.00400 -23.51200 -47.87200 1.000 75.47082  ? 356 LEU B CG  1 
ATOM   6295 C CD1 . LEU B 1 356 ? -66.48100 -24.87700 -47.93400 1.000 73.80454  ? 356 LEU B CD1 1 
ATOM   6296 C CD2 . LEU B 1 356 ? -68.24000 -23.36600 -48.74600 1.000 74.04245  ? 356 LEU B CD2 1 
ATOM   6297 N N   . LEU B 1 357 ? -69.54700 -20.82500 -44.83700 1.000 82.65334  ? 357 LEU B N   1 
ATOM   6298 C CA  . LEU B 1 357 ? -70.60500 -20.73300 -43.84700 1.000 82.44202  ? 357 LEU B CA  1 
ATOM   6299 C C   . LEU B 1 357 ? -71.80700 -21.53200 -44.33900 1.000 90.89587  ? 357 LEU B C   1 
ATOM   6300 O O   . LEU B 1 357 ? -72.95200 -21.24400 -43.97100 1.000 94.46769  ? 357 LEU B O   1 
ATOM   6301 C CB  . LEU B 1 357 ? -70.96100 -19.26600 -43.59400 1.000 81.77748  ? 357 LEU B CB  1 
ATOM   6302 C CG  . LEU B 1 357 ? -69.77700 -18.31700 -43.36000 1.000 79.64764  ? 357 LEU B CG  1 
ATOM   6303 C CD1 . LEU B 1 357 ? -70.24400 -16.89400 -43.04200 1.000 79.11195  ? 357 LEU B CD1 1 
ATOM   6304 C CD2 . LEU B 1 357 ? -68.86600 -18.84000 -42.25600 1.000 76.26556  ? 357 LEU B CD2 1 
ATOM   6305 N N   . GLY B 1 358 ? -71.55100 -22.53600 -45.18200 1.000 95.65370  ? 358 GLY B N   1 
ATOM   6306 C CA  . GLY B 1 358 ? -72.59000 -23.39800 -45.71100 1.000 98.66480  ? 358 GLY B CA  1 
ATOM   6307 C C   . GLY B 1 358 ? -72.88100 -23.19200 -47.18500 1.000 97.12645  ? 358 GLY B C   1 
ATOM   6308 O O   . GLY B 1 358 ? -72.42900 -23.97700 -48.02400 1.000 94.59742  ? 358 GLY B O   1 
ATOM   6309 N N   . GLU B 1 359 ? -73.62700 -22.12400 -47.49800 1.000 101.09935 ? 359 GLU B N   1 
ATOM   6310 C CA  . GLU B 1 359 ? -74.17200 -21.83400 -48.82500 1.000 102.10438 ? 359 GLU B CA  1 
ATOM   6311 C C   . GLU B 1 359 ? -73.13400 -21.91000 -49.94200 1.000 98.32560  ? 359 GLU B C   1 
ATOM   6312 O O   . GLU B 1 359 ? -72.80200 -22.99700 -50.43000 1.000 91.37441  ? 359 GLU B O   1 
ATOM   6313 C CB  . GLU B 1 359 ? -74.81900 -20.44100 -48.81800 1.000 97.71382  ? 359 GLU B CB  1 
ATOM   6314 C CG  . GLU B 1 359 ? -75.64000 -20.10200 -50.06400 1.000 104.34677 ? 359 GLU B CG  1 
ATOM   6315 C CD  . GLU B 1 359 ? -75.66400 -18.61000 -50.36000 1.000 106.79474 ? 359 GLU B CD  1 
ATOM   6316 O OE1 . GLU B 1 359 ? -75.58100 -17.80800 -49.40300 1.000 110.91310 ? 359 GLU B OE1 1 
ATOM   6317 O OE2 . GLU B 1 359 ? -75.75800 -18.24100 -51.55000 1.000 96.26657  ? 359 GLU B OE2 1 
ATOM   6318 N N   . GLU B 1 360 ? -72.64000 -20.75300 -50.37300 1.000 96.71974  ? 360 GLU B N   1 
ATOM   6319 C CA  . GLU B 1 360 ? -71.64000 -20.67800 -51.41900 1.000 96.30371  ? 360 GLU B CA  1 
ATOM   6320 C C   . GLU B 1 360 ? -70.31400 -20.24300 -50.81700 1.000 88.56965  ? 360 GLU B C   1 
ATOM   6321 O O   . GLU B 1 360 ? -70.30500 -19.41900 -49.89700 1.000 87.13367  ? 360 GLU B O   1 
ATOM   6322 C CB  . GLU B 1 360 ? -72.04800 -19.68000 -52.51500 1.000 96.50782  ? 360 GLU B CB  1 
ATOM   6323 C CG  . GLU B 1 360 ? -73.49500 -19.81500 -53.00300 1.000 101.13587 ? 360 GLU B CG  1 
ATOM   6324 C CD  . GLU B 1 360 ? -73.66900 -20.85300 -54.10100 1.000 101.35421 ? 360 GLU B CD  1 
ATOM   6325 O OE1 . GLU B 1 360 ? -73.38200 -20.53800 -55.28100 1.000 98.42971  ? 360 GLU B OE1 1 
ATOM   6326 O OE2 . GLU B 1 360 ? -74.09400 -21.98400 -53.77900 1.000 97.98519  ? 360 GLU B OE2 1 
ATOM   6327 N N   . PRO B 1 361 ? -69.18600 -20.78400 -51.29100 1.000 82.18978  ? 361 PRO B N   1 
ATOM   6328 C CA  . PRO B 1 361 ? -67.88900 -20.26200 -50.84600 1.000 77.54785  ? 361 PRO B CA  1 
ATOM   6329 C C   . PRO B 1 361 ? -67.84400 -18.74600 -50.95900 1.000 71.46626  ? 361 PRO B C   1 
ATOM   6330 O O   . PRO B 1 361 ? -68.00300 -18.19900 -52.05300 1.000 72.58270  ? 361 PRO B O   1 
ATOM   6331 C CB  . PRO B 1 361 ? -66.89600 -20.93900 -51.79800 1.000 77.50522  ? 361 PRO B CB  1 
ATOM   6332 C CG  . PRO B 1 361 ? -67.56700 -22.22200 -52.17700 1.000 76.57363  ? 361 PRO B CG  1 
ATOM   6333 C CD  . PRO B 1 361 ? -69.03700 -21.90100 -52.24300 1.000 82.96173  ? 361 PRO B CD  1 
ATOM   6334 N N   . LEU B 1 362 ? -67.70100 -18.06100 -49.82500 1.000 66.38789  ? 362 LEU B N   1 
ATOM   6335 C CA  . LEU B 1 362 ? -67.49600 -16.61600 -49.79700 1.000 63.74849  ? 362 LEU B CA  1 
ATOM   6336 C C   . LEU B 1 362 ? -65.99500 -16.37500 -49.87200 1.000 60.46286  ? 362 LEU B C   1 
ATOM   6337 O O   . LEU B 1 362 ? -65.27100 -16.62900 -48.90500 1.000 57.18556  ? 362 LEU B O   1 
ATOM   6338 C CB  . LEU B 1 362 ? -68.10100 -16.00500 -48.53500 1.000 60.33657  ? 362 LEU B CB  1 
ATOM   6339 C CG  . LEU B 1 362 ? -68.15800 -14.48400 -48.31300 1.000 66.16234  ? 362 LEU B CG  1 
ATOM   6340 C CD1 . LEU B 1 362 ? -66.92200 -13.95100 -47.59400 1.000 71.67638  ? 362 LEU B CD1 1 
ATOM   6341 C CD2 . LEU B 1 362 ? -68.40100 -13.72000 -49.61400 1.000 64.93246  ? 362 LEU B CD2 1 
ATOM   6342 N N   . LEU B 1 363 ? -65.52200 -15.91200 -51.02300 1.000 61.21572  ? 363 LEU B N   1 
ATOM   6343 C CA  . LEU B 1 363 ? -64.09300 -15.83700 -51.29400 1.000 55.76360  ? 363 LEU B CA  1 
ATOM   6344 C C   . LEU B 1 363 ? -63.61500 -14.40600 -51.08300 1.000 58.45916  ? 363 LEU B C   1 
ATOM   6345 O O   . LEU B 1 363 ? -64.09700 -13.47700 -51.74700 1.000 52.02243  ? 363 LEU B O   1 
ATOM   6346 C CB  . LEU B 1 363 ? -63.78600 -16.32400 -52.70700 1.000 55.08561  ? 363 LEU B CB  1 
ATOM   6347 C CG  . LEU B 1 363 ? -64.29500 -17.74300 -52.98600 1.000 60.03009  ? 363 LEU B CG  1 
ATOM   6348 C CD1 . LEU B 1 363 ? -63.70900 -18.31300 -54.26400 1.000 61.31142  ? 363 LEU B CD1 1 
ATOM   6349 C CD2 . LEU B 1 363 ? -64.00900 -18.67200 -51.82600 1.000 55.39266  ? 363 LEU B CD2 1 
ATOM   6350 N N   . VAL B 1 364 ? -62.68200 -14.23700 -50.14000 1.000 48.82796  ? 364 VAL B N   1 
ATOM   6351 C CA  . VAL B 1 364 ? -62.09300 -12.94500 -49.82500 1.000 42.30311  ? 364 VAL B CA  1 
ATOM   6352 C C   . VAL B 1 364 ? -60.64900 -12.94700 -50.28900 1.000 47.00364  ? 364 VAL B C   1 
ATOM   6353 O O   . VAL B 1 364 ? -59.96700 -13.97700 -50.25700 1.000 50.43877  ? 364 VAL B O   1 
ATOM   6354 C CB  . VAL B 1 364 ? -62.14600 -12.63300 -48.32000 1.000 44.46546  ? 364 VAL B CB  1 
ATOM   6355 C CG1 . VAL B 1 364 ? -61.89600 -11.14500 -48.06600 1.000 48.33851  ? 364 VAL B CG1 1 
ATOM   6356 C CG2 . VAL B 1 364 ? -63.44000 -13.11700 -47.71900 1.000 46.02268  ? 364 VAL B CG2 1 
ATOM   6357 N N   . GLY B 1 365 ? -60.18100 -11.77500 -50.70400 1.000 42.79700  ? 365 GLY B N   1 
ATOM   6358 C CA  . GLY B 1 365 ? -58.79200 -11.61700 -51.04900 1.000 35.72839  ? 365 GLY B CA  1 
ATOM   6359 C C   . GLY B 1 365 ? -58.39700 -12.46900 -52.23700 1.000 44.63880  ? 365 GLY B C   1 
ATOM   6360 O O   . GLY B 1 365 ? -59.17500 -12.70600 -53.17400 1.000 44.57888  ? 365 GLY B O   1 
ATOM   6361 N N   . CYS B 1 366 ? -57.16000 -12.96400 -52.17600 1.000 44.59241  ? 366 CYS B N   1 
ATOM   6362 C CA  . CYS B 1 366 ? -56.50400 -13.62600 -53.29800 1.000 45.94722  ? 366 CYS B CA  1 
ATOM   6363 C C   . CYS B 1 366 ? -56.67000 -15.12700 -53.11900 1.000 49.20428  ? 366 CYS B C   1 
ATOM   6364 O O   . CYS B 1 366 ? -55.94200 -15.76100 -52.34900 1.000 43.78342  ? 366 CYS B O   1 
ATOM   6365 C CB  . CYS B 1 366 ? -55.03800 -13.21900 -53.36600 1.000 49.41936  ? 366 CYS B CB  1 
ATOM   6366 S SG  . CYS B 1 366 ? -54.27500 -13.62500 -54.92200 1.000 69.34069  ? 366 CYS B SG  1 
ATOM   6367 N N   . THR B 1 367 ? -57.62400 -15.69400 -53.84500 1.000 49.36821  ? 367 THR B N   1 
ATOM   6368 C CA  . THR B 1 367 ? -58.12400 -17.03900 -53.63200 1.000 46.91757  ? 367 THR B CA  1 
ATOM   6369 C C   . THR B 1 367 ? -58.19100 -17.80300 -54.94500 1.000 52.63696  ? 367 THR B C   1 
ATOM   6370 O O   . THR B 1 367 ? -58.17300 -17.19900 -56.02500 1.000 52.00988  ? 367 THR B O   1 
ATOM   6371 C CB  . THR B 1 367 ? -59.51900 -16.96400 -52.99900 1.000 52.09710  ? 367 THR B CB  1 
ATOM   6372 O OG1 . THR B 1 367 ? -59.80900 -18.20200 -52.35000 1.000 57.23261  ? 367 THR B OG1 1 
ATOM   6373 C CG2 . THR B 1 367 ? -60.57100 -16.68000 -54.05800 1.000 47.99812  ? 367 THR B CG2 1 
ATOM   6374 N N   . PRO B 1 368 ? -58.24400 -19.13500 -54.89500 1.000 53.97125  ? 368 PRO B N   1 
ATOM   6375 C CA  . PRO B 1 368 ? -58.57600 -19.90100 -56.10400 1.000 57.01969  ? 368 PRO B CA  1 
ATOM   6376 C C   . PRO B 1 368 ? -60.03100 -19.67400 -56.49700 1.000 60.22082  ? 368 PRO B C   1 
ATOM   6377 O O   . PRO B 1 368 ? -60.84000 -19.14400 -55.73500 1.000 62.46116  ? 368 PRO B O   1 
ATOM   6378 C CB  . PRO B 1 368 ? -58.33400 -21.36300 -55.70200 1.000 53.66699  ? 368 PRO B CB  1 
ATOM   6379 C CG  . PRO B 1 368 ? -57.51500 -21.30300 -54.45200 1.000 47.72589  ? 368 PRO B CG  1 
ATOM   6380 C CD  . PRO B 1 368 ? -57.90800 -20.02500 -53.76800 1.000 49.00168  ? 368 PRO B CD  1 
ATOM   6381 N N   . ALA B 1 369 ? -60.36300 -20.10200 -57.71200 1.000 64.37051  ? 369 ALA B N   1 
ATOM   6382 C CA  . ALA B 1 369 ? -61.71600 -19.93400 -58.21600 1.000 65.49000  ? 369 ALA B CA  1 
ATOM   6383 C C   . ALA B 1 369 ? -62.69700 -20.78200 -57.40800 1.000 67.85856  ? 369 ALA B C   1 
ATOM   6384 O O   . ALA B 1 369 ? -62.31200 -21.72000 -56.69900 1.000 70.08495  ? 369 ALA B O   1 
ATOM   6385 C CB  . ALA B 1 369 ? -61.78500 -20.29800 -59.69800 1.000 66.55247  ? 369 ALA B CB  1 
ATOM   6386 N N   . GLN B 1 370 ? -63.98400 -20.44100 -57.53400 1.000 61.81233  ? 370 GLN B N   1 
ATOM   6387 C CA  . GLN B 1 370 ? -65.02600 -21.05500 -56.71400 1.000 62.27991  ? 370 GLN B CA  1 
ATOM   6388 C C   . GLN B 1 370 ? -65.02700 -22.57800 -56.81900 1.000 69.70478  ? 370 GLN B C   1 
ATOM   6389 O O   . GLN B 1 370 ? -64.95400 -23.27800 -55.80100 1.000 68.88980  ? 370 GLN B O   1 
ATOM   6390 C CB  . GLN B 1 370 ? -66.38500 -20.49800 -57.11100 1.000 63.82841  ? 370 GLN B CB  1 
ATOM   6391 C CG  . GLN B 1 370 ? -67.51800 -21.15400 -56.37600 1.000 66.71971  ? 370 GLN B CG  1 
ATOM   6392 C CD  . GLN B 1 370 ? -68.71800 -20.25800 -56.30700 1.000 75.51464  ? 370 GLN B CD  1 
ATOM   6393 O OE1 . GLN B 1 370 ? -69.63000 -20.47500 -55.51000 1.000 82.96911  ? 370 GLN B OE1 1 
ATOM   6394 N NE2 . GLN B 1 370 ? -68.72500 -19.22700 -57.14300 1.000 73.33189  ? 370 GLN B NE2 1 
ATOM   6395 N N   . ASP B 1 371 ? -65.13200 -23.11400 -58.04400 1.000 69.62955  ? 371 ASP B N   1 
ATOM   6396 C CA  . ASP B 1 371 ? -65.13400 -24.56700 -58.22500 1.000 69.92846  ? 371 ASP B CA  1 
ATOM   6397 C C   . ASP B 1 371 ? -63.95000 -25.20400 -57.52000 1.000 69.42336  ? 371 ASP B C   1 
ATOM   6398 O O   . ASP B 1 371 ? -64.11000 -26.15900 -56.75300 1.000 73.24212  ? 371 ASP B O   1 
ATOM   6399 C CB  . ASP B 1 371 ? -65.10400 -24.94500 -59.70900 1.000 75.00480  ? 371 ASP B CB  1 
ATOM   6400 C CG  . ASP B 1 371 ? -65.09600 -23.74200 -60.62500 1.000 80.86239  ? 371 ASP B CG  1 
ATOM   6401 O OD1 . ASP B 1 371 ? -66.18900 -23.18200 -60.87200 1.000 79.88057  ? 371 ASP B OD1 1 
ATOM   6402 O OD2 . ASP B 1 371 ? -63.99900 -23.35600 -61.09400 1.000 78.45355  ? 371 ASP B OD2 1 
ATOM   6403 N N   . GLU B 1 372 ? -62.75000 -24.67000 -57.75900 1.000 69.43452  ? 372 GLU B N   1 
ATOM   6404 C CA  . GLU B 1 372 ? -61.54600 -25.23500 -57.16200 1.000 69.13906  ? 372 GLU B CA  1 
ATOM   6405 C C   . GLU B 1 372 ? -61.60500 -25.23100 -55.64100 1.000 66.65613  ? 372 GLU B C   1 
ATOM   6406 O O   . GLU B 1 372 ? -61.03800 -26.12600 -54.99800 1.000 66.56042  ? 372 GLU B O   1 
ATOM   6407 C CB  . GLU B 1 372 ? -60.32100 -24.45900 -57.63300 1.000 71.93366  ? 372 GLU B CB  1 
ATOM   6408 C CG  . GLU B 1 372 ? -60.10200 -24.46700 -59.12900 1.000 64.50097  ? 372 GLU B CG  1 
ATOM   6409 C CD  . GLU B 1 372 ? -59.02600 -23.47500 -59.53200 1.000 68.91700  ? 372 GLU B CD  1 
ATOM   6410 O OE1 . GLU B 1 372 ? -59.32400 -22.26000 -59.55400 1.000 72.26421  ? 372 GLU B OE1 1 
ATOM   6411 O OE2 . GLU B 1 372 ? -57.87800 -23.90300 -59.79300 1.000 67.25362  ? 372 GLU B OE2 1 
ATOM   6412 N N   . VAL B 1 373 ? -62.26900 -24.23500 -55.04700 1.000 62.50826  ? 373 VAL B N   1 
ATOM   6413 C CA  . VAL B 1 373 ? -62.46100 -24.24000 -53.59800 1.000 63.67995  ? 373 VAL B CA  1 
ATOM   6414 C C   . VAL B 1 373 ? -63.21600 -25.49600 -53.17800 1.000 66.47857  ? 373 VAL B C   1 
ATOM   6415 O O   . VAL B 1 373 ? -62.70100 -26.33700 -52.43000 1.000 64.03359  ? 373 VAL B O   1 
ATOM   6416 C CB  . VAL B 1 373 ? -63.19700 -22.96800 -53.14000 1.000 60.73938  ? 373 VAL B CB  1 
ATOM   6417 C CG1 . VAL B 1 373 ? -63.53900 -23.06800 -51.66900 1.000 63.95343  ? 373 VAL B CG1 1 
ATOM   6418 C CG2 . VAL B 1 373 ? -62.35800 -21.73700 -53.39300 1.000 56.82254  ? 373 VAL B CG2 1 
ATOM   6419 N N   . GLU B 1 374 ? -64.43600 -25.65500 -53.69600 1.000 67.59612  ? 374 GLU B N   1 
ATOM   6420 C CA  . GLU B 1 374 ? -65.29000 -26.76900 -53.29500 1.000 66.21413  ? 374 GLU B CA  1 
ATOM   6421 C C   . GLU B 1 374 ? -64.59900 -28.11200 -53.49500 1.000 67.83987  ? 374 GLU B C   1 
ATOM   6422 O O   . GLU B 1 374 ? -64.73500 -29.01600 -52.66300 1.000 70.08513  ? 374 GLU B O   1 
ATOM   6423 C CB  . GLU B 1 374 ? -66.59600 -26.70300 -54.07500 1.000 64.87967  ? 374 GLU B CB  1 
ATOM   6424 C CG  . GLU B 1 374 ? -66.94400 -25.27700 -54.44200 1.000 75.32350  ? 374 GLU B CG  1 
ATOM   6425 C CD  . GLU B 1 374 ? -68.33600 -25.12500 -55.01500 1.000 82.56813  ? 374 GLU B CD  1 
ATOM   6426 O OE1 . GLU B 1 374 ? -68.52900 -25.46800 -56.20500 1.000 81.13199  ? 374 GLU B OE1 1 
ATOM   6427 O OE2 . GLU B 1 374 ? -69.23300 -24.65800 -54.27600 1.000 80.64082  ? 374 GLU B OE2 1 
ATOM   6428 N N   . ALA B 1 375 ? -63.84300 -28.25900 -54.58300 1.000 63.74962  ? 375 ALA B N   1 
ATOM   6429 C CA  . ALA B 1 375 ? -63.10000 -29.49300 -54.80100 1.000 60.22981  ? 375 ALA B CA  1 
ATOM   6430 C C   . ALA B 1 375 ? -62.04500 -29.68600 -53.72100 1.000 66.13406  ? 375 ALA B C   1 
ATOM   6431 O O   . ALA B 1 375 ? -61.92600 -30.77000 -53.14000 1.000 68.08179  ? 375 ALA B O   1 
ATOM   6432 C CB  . ALA B 1 375 ? -62.46100 -29.48400 -56.18900 1.000 65.05431  ? 375 ALA B CB  1 
ATOM   6433 N N   . LEU B 1 376 ? -61.25200 -28.64500 -53.44800 1.000 66.18358  ? 376 LEU B N   1 
ATOM   6434 C CA  . LEU B 1 376 ? -60.37900 -28.69000 -52.28000 1.000 66.53611  ? 376 LEU B CA  1 
ATOM   6435 C C   . LEU B 1 376 ? -61.18000 -28.98200 -51.01900 1.000 67.96046  ? 376 LEU B C   1 
ATOM   6436 O O   . LEU B 1 376 ? -60.71400 -29.69800 -50.11900 1.000 64.66096  ? 376 LEU B O   1 
ATOM   6437 C CB  . LEU B 1 376 ? -59.63500 -27.36200 -52.14000 1.000 60.89738  ? 376 LEU B CB  1 
ATOM   6438 C CG  . LEU B 1 376 ? -59.01000 -27.11500 -50.77000 1.000 54.41736  ? 376 LEU B CG  1 
ATOM   6439 C CD1 . LEU B 1 376 ? -57.68900 -27.87500 -50.64500 1.000 48.02156  ? 376 LEU B CD1 1 
ATOM   6440 C CD2 . LEU B 1 376 ? -58.85100 -25.62500 -50.50500 1.000 50.04968  ? 376 LEU B CD2 1 
ATOM   6441 N N   . VAL B 1 377 ? -62.40900 -28.47300 -50.96800 1.000 62.16862  ? 377 VAL B N   1 
ATOM   6442 C CA  . VAL B 1 377 ? -63.21700 -28.52400 -49.76000 1.000 65.70171  ? 377 VAL B CA  1 
ATOM   6443 C C   . VAL B 1 377 ? -63.81200 -29.91200 -49.55800 1.000 67.13336  ? 377 VAL B C   1 
ATOM   6444 O O   . VAL B 1 377 ? -63.76100 -30.46900 -48.45500 1.000 68.41063  ? 377 VAL B O   1 
ATOM   6445 C CB  . VAL B 1 377 ? -64.30700 -27.44300 -49.83400 1.000 63.66778  ? 377 VAL B CB  1 
ATOM   6446 C CG1 . VAL B 1 377 ? -65.46300 -27.83200 -48.97500 1.000 62.97047  ? 377 VAL B CG1 1 
ATOM   6447 C CG2 . VAL B 1 377 ? -63.73700 -26.09000 -49.43300 1.000 63.20367  ? 377 VAL B CG2 1 
ATOM   6448 N N   . ALA B 1 378 ? -64.40600 -30.47800 -50.61200 1.000 65.42567  ? 378 ALA B N   1 
ATOM   6449 C CA  . ALA B 1 378 ? -64.89200 -31.85000 -50.53800 1.000 65.25395  ? 378 ALA B CA  1 
ATOM   6450 C C   . ALA B 1 378 ? -63.79800 -32.78100 -50.03200 1.000 68.90840  ? 378 ALA B C   1 
ATOM   6451 O O   . ALA B 1 378 ? -63.99900 -33.53200 -49.07000 1.000 73.84819  ? 378 ALA B O   1 
ATOM   6452 C CB  . ALA B 1 378 ? -65.40100 -32.29900 -51.90700 1.000 63.74983  ? 378 ALA B CB  1 
ATOM   6453 N N   . TRP B 1 379 ? -62.61200 -32.70200 -50.64600 1.000 62.16473  ? 379 TRP B N   1 
ATOM   6454 C CA  . TRP B 1 379 ? -61.45700 -33.49500 -50.22600 1.000 70.26082  ? 379 TRP B CA  1 
ATOM   6455 C C   . TRP B 1 379 ? -61.06200 -33.27100 -48.76100 1.000 74.78357  ? 379 TRP B C   1 
ATOM   6456 O O   . TRP B 1 379 ? -60.41400 -34.14300 -48.16100 1.000 69.96410  ? 379 TRP B O   1 
ATOM   6457 C CB  . TRP B 1 379 ? -60.27200 -33.16800 -51.13800 1.000 63.61935  ? 379 TRP B CB  1 
ATOM   6458 C CG  . TRP B 1 379 ? -58.99100 -33.81200 -50.72600 1.000 66.93471  ? 379 TRP B CG  1 
ATOM   6459 C CD1 . TRP B 1 379 ? -58.54200 -35.04700 -51.08900 1.000 69.12190  ? 379 TRP B CD1 1 
ATOM   6460 C CD2 . TRP B 1 379 ? -57.98300 -33.25400 -49.87200 1.000 64.95759  ? 379 TRP B CD2 1 
ATOM   6461 N NE1 . TRP B 1 379 ? -57.31500 -35.29100 -50.52100 1.000 70.03820  ? 379 TRP B NE1 1 
ATOM   6462 C CE2 . TRP B 1 379 ? -56.95000 -34.20500 -49.77000 1.000 65.58101  ? 379 TRP B CE2 1 
ATOM   6463 C CE3 . TRP B 1 379 ? -57.85100 -32.03900 -49.19300 1.000 64.26173  ? 379 TRP B CE3 1 
ATOM   6464 C CZ2 . TRP B 1 379 ? -55.80200 -33.98300 -49.01500 1.000 65.69825  ? 379 TRP B CZ2 1 
ATOM   6465 C CZ3 . TRP B 1 379 ? -56.71200 -31.82200 -48.44300 1.000 64.32306  ? 379 TRP B CZ3 1 
ATOM   6466 C CH2 . TRP B 1 379 ? -55.70100 -32.79000 -48.36100 1.000 62.55124  ? 379 TRP B CH2 1 
ATOM   6467 N N   . LEU B 1 380 ? -61.43100 -32.13000 -48.17200 1.000 72.65208  ? 380 LEU B N   1 
ATOM   6468 C CA  . LEU B 1 380 ? -60.93500 -31.78900 -46.84200 1.000 71.21700  ? 380 LEU B CA  1 
ATOM   6469 C C   . LEU B 1 380 ? -61.67200 -32.54800 -45.73900 1.000 70.84066  ? 380 LEU B C   1 
ATOM   6470 O O   . LEU B 1 380 ? -61.06000 -32.93400 -44.73400 1.000 69.19100  ? 380 LEU B O   1 
ATOM   6471 C CB  . LEU B 1 380 ? -61.05500 -30.27900 -46.62200 1.000 70.91115  ? 380 LEU B CB  1 
ATOM   6472 C CG  . LEU B 1 380 ? -59.78300 -29.43600 -46.55400 1.000 65.62884  ? 380 LEU B CG  1 
ATOM   6473 C CD1 . LEU B 1 380 ? -60.18800 -27.99200 -46.31200 1.000 59.92062  ? 380 LEU B CD1 1 
ATOM   6474 C CD2 . LEU B 1 380 ? -58.82300 -29.93300 -45.46800 1.000 55.68562  ? 380 LEU B CD2 1 
ATOM   6475 N N   . ALA B 1 381 ? -62.98200 -32.76500 -45.90600 1.000 71.84963  ? 381 ALA B N   1 
ATOM   6476 C CA  . ALA B 1 381 ? -63.78100 -33.39600 -44.85700 1.000 74.62695  ? 381 ALA B CA  1 
ATOM   6477 C C   . ALA B 1 381 ? -63.35500 -34.84000 -44.59200 1.000 74.40749  ? 381 ALA B C   1 
ATOM   6478 O O   . ALA B 1 381 ? -63.44800 -35.31800 -43.45300 1.000 68.56111  ? 381 ALA B O   1 
ATOM   6479 C CB  . ALA B 1 381 ? -65.26200 -33.33500 -45.23000 1.000 73.65655  ? 381 ALA B CB  1 
ATOM   6480 N N   . THR B 1 382 ? -62.87600 -35.54300 -45.62100 1.000 75.59913  ? 382 THR B N   1 
ATOM   6481 C CA  . THR B 1 382 ? -62.42000 -36.92800 -45.54100 1.000 75.43454  ? 382 THR B CA  1 
ATOM   6482 C C   . THR B 1 382 ? -61.03400 -37.07500 -44.90300 1.000 76.34268  ? 382 THR B C   1 
ATOM   6483 O O   . THR B 1 382 ? -60.37000 -38.10000 -45.10800 1.000 76.38064  ? 382 THR B O   1 
ATOM   6484 C CB  . THR B 1 382 ? -62.39300 -37.54400 -46.94000 1.000 77.48795  ? 382 THR B CB  1 
ATOM   6485 O OG1 . THR B 1 382 ? -61.11700 -37.29000 -47.54700 1.000 78.18435  ? 382 THR B OG1 1 
ATOM   6486 C CG2 . THR B 1 382 ? -63.49800 -36.93000 -47.81500 1.000 74.12891  ? 382 THR B CG2 1 
ATOM   6487 N N   . GLN B 1 383 ? -60.58400 -36.08900 -44.16500 1.000 74.57710  ? 383 GLN B N   1 
ATOM   6488 C CA  . GLN B 1 383 ? -59.26700 -36.18000 -43.58500 1.000 74.67881  ? 383 GLN B CA  1 
ATOM   6489 C C   . GLN B 1 383 ? -59.36100 -36.34600 -42.06900 1.000 74.64617  ? 383 GLN B C   1 
ATOM   6490 O O   . GLN B 1 383 ? -60.34100 -35.92100 -41.44400 1.000 72.31127  ? 383 GLN B O   1 
ATOM   6491 C CB  . GLN B 1 383 ? -58.45100 -34.93000 -43.93600 1.000 73.63684  ? 383 GLN B CB  1 
ATOM   6492 C CG  . GLN B 1 383 ? -58.30500 -34.70800 -45.43300 1.000 71.92808  ? 383 GLN B CG  1 
ATOM   6493 C CD  . GLN B 1 383 ? -57.45400 -35.78300 -46.10100 1.000 76.52537  ? 383 GLN B CD  1 
ATOM   6494 O OE1 . GLN B 1 383 ? -57.89600 -36.44700 -47.04300 1.000 73.39572  ? 383 GLN B OE1 1 
ATOM   6495 N NE2 . GLN B 1 383 ? -56.22300 -35.95400 -45.61600 1.000 74.19902  ? 383 GLN B NE2 1 
ATOM   6496 N N   . PRO B 1 384 ? -58.36400 -36.98000 -41.45600 1.000 76.58390  ? 384 PRO B N   1 
ATOM   6497 C CA  . PRO B 1 384 ? -58.38700 -37.23300 -40.00400 1.000 76.65354  ? 384 PRO B CA  1 
ATOM   6498 C C   . PRO B 1 384 ? -57.75300 -36.10300 -39.19100 1.000 80.37683  ? 384 PRO B C   1 
ATOM   6499 O O   . PRO B 1 384 ? -56.79700 -36.30500 -38.42300 1.000 84.55720  ? 384 PRO B O   1 
ATOM   6500 C CB  . PRO B 1 384 ? -57.59000 -38.53700 -39.89700 1.000 84.62222  ? 384 PRO B CB  1 
ATOM   6501 C CG  . PRO B 1 384 ? -56.54900 -38.39900 -40.97500 1.000 83.23851  ? 384 PRO B CG  1 
ATOM   6502 C CD  . PRO B 1 384 ? -57.22000 -37.64300 -42.11100 1.000 83.24198  ? 384 PRO B CD  1 
ATOM   6503 N N   . PHE B 1 385 ? -58.27900 -34.89500 -39.35400 1.000 73.32962  ? 385 PHE B N   1 
ATOM   6504 C CA  . PHE B 1 385 ? -57.88900 -33.77600 -38.51300 1.000 76.46808  ? 385 PHE B CA  1 
ATOM   6505 C C   . PHE B 1 385 ? -59.11600 -33.29700 -37.75600 1.000 74.11206  ? 385 PHE B C   1 
ATOM   6506 O O   . PHE B 1 385 ? -60.23000 -33.31500 -38.29100 1.000 69.75690  ? 385 PHE B O   1 
ATOM   6507 C CB  . PHE B 1 385 ? -57.28000 -32.63500 -39.32600 1.000 70.88402  ? 385 PHE B CB  1 
ATOM   6508 C CG  . PHE B 1 385 ? -58.26200 -31.92900 -40.19300 1.000 65.50631  ? 385 PHE B CG  1 
ATOM   6509 C CD1 . PHE B 1 385 ? -58.57700 -32.42700 -41.43900 1.000 67.88642  ? 385 PHE B CD1 1 
ATOM   6510 C CD2 . PHE B 1 385 ? -58.86700 -30.76100 -39.76500 1.000 63.64324  ? 385 PHE B CD2 1 
ATOM   6511 C CE1 . PHE B 1 385 ? -59.48200 -31.77400 -42.24600 1.000 72.23864  ? 385 PHE B CE1 1 
ATOM   6512 C CE2 . PHE B 1 385 ? -59.76800 -30.10000 -40.56200 1.000 65.91597  ? 385 PHE B CE2 1 
ATOM   6513 C CZ  . PHE B 1 385 ? -60.07800 -30.60400 -41.80700 1.000 68.97260  ? 385 PHE B CZ  1 
ATOM   6514 N N   . GLN B 1 386 ? -58.89600 -32.86300 -36.51300 1.000 70.06224  ? 386 GLN B N   1 
ATOM   6515 C CA  . GLN B 1 386 ? -59.99600 -32.59400 -35.58600 1.000 67.70340  ? 386 GLN B CA  1 
ATOM   6516 C C   . GLN B 1 386 ? -60.65700 -31.24200 -35.84900 1.000 70.26452  ? 386 GLN B C   1 
ATOM   6517 O O   . GLN B 1 386 ? -61.79600 -31.17200 -36.32300 1.000 67.68719  ? 386 GLN B O   1 
ATOM   6518 C CB  . GLN B 1 386 ? -59.47000 -32.67400 -34.15100 1.000 72.77538  ? 386 GLN B CB  1 
ATOM   6519 C CG  . GLN B 1 386 ? -59.44400 -34.07100 -33.56200 1.000 75.15945  ? 386 GLN B CG  1 
ATOM   6520 C CD  . GLN B 1 386 ? -60.62600 -34.31700 -32.63400 1.000 86.42773  ? 386 GLN B CD  1 
ATOM   6521 O OE1 . GLN B 1 386 ? -61.60200 -33.55600 -32.63500 1.000 82.57392  ? 386 GLN B OE1 1 
ATOM   6522 N NE2 . GLN B 1 386 ? -60.53900 -35.37500 -31.82600 1.000 86.62610  ? 386 GLN B NE2 1 
ATOM   6523 N N   . THR B 1 387 ? -59.95700 -30.15300 -35.51300 1.000 64.43408  ? 387 THR B N   1 
ATOM   6524 C CA  . THR B 1 387 ? -60.46900 -28.80100 -35.69300 1.000 68.19451  ? 387 THR B CA  1 
ATOM   6525 C C   . THR B 1 387 ? -59.71500 -27.99300 -36.74300 1.000 63.38904  ? 387 THR B C   1 
ATOM   6526 O O   . THR B 1 387 ? -60.20000 -26.92900 -37.14100 1.000 55.34068  ? 387 THR B O   1 
ATOM   6527 C CB  . THR B 1 387 ? -60.44200 -28.02200 -34.36000 1.000 67.76819  ? 387 THR B CB  1 
ATOM   6528 O OG1 . THR B 1 387 ? -59.23800 -28.32100 -33.63300 1.000 68.46352  ? 387 THR B OG1 1 
ATOM   6529 C CG2 . THR B 1 387 ? -61.66600 -28.35900 -33.50700 1.000 59.22329  ? 387 THR B CG2 1 
ATOM   6530 N N   . SER B 1 388 ? -58.55300 -28.45500 -37.20000 1.000 62.04648  ? 388 SER B N   1 
ATOM   6531 C CA  . SER B 1 388 ? -57.74900 -27.63600 -38.09000 1.000 57.27841  ? 388 SER B CA  1 
ATOM   6532 C C   . SER B 1 388 ? -56.74400 -28.50400 -38.82400 1.000 58.71637  ? 388 SER B C   1 
ATOM   6533 O O   . SER B 1 388 ? -56.16400 -29.42500 -38.24000 1.000 59.03549  ? 388 SER B O   1 
ATOM   6534 C CB  . SER B 1 388 ? -57.02000 -26.53400 -37.31800 1.000 59.04423  ? 388 SER B CB  1 
ATOM   6535 O OG  . SER B 1 388 ? -56.05000 -27.09600 -36.44900 1.000 60.51692  ? 388 SER B OG  1 
ATOM   6536 N N   . PHE B 1 389 ? -56.54600 -28.19100 -40.10800 1.000 63.17536  ? 389 PHE B N   1 
ATOM   6537 C CA  . PHE B 1 389 ? -55.53400 -28.81300 -40.95300 1.000 60.74893  ? 389 PHE B CA  1 
ATOM   6538 C C   . PHE B 1 389 ? -54.70400 -27.72500 -41.62800 1.000 55.28507  ? 389 PHE B C   1 
ATOM   6539 O O   . PHE B 1 389 ? -55.25500 -26.71800 -42.08800 1.000 49.07196  ? 389 PHE B O   1 
ATOM   6540 C CB  . PHE B 1 389 ? -56.17900 -29.72600 -42.00800 1.000 62.59492  ? 389 PHE B CB  1 
ATOM   6541 C CG  . PHE B 1 389 ? -55.18800 -30.37700 -42.92300 1.000 61.75708  ? 389 PHE B CG  1 
ATOM   6542 C CD1 . PHE B 1 389 ? -54.43800 -31.45500 -42.49200 1.000 57.58124  ? 389 PHE B CD1 1 
ATOM   6543 C CD2 . PHE B 1 389 ? -54.99600 -29.89800 -44.20700 1.000 61.04607  ? 389 PHE B CD2 1 
ATOM   6544 C CE1 . PHE B 1 389 ? -53.52000 -32.04400 -43.32700 1.000 64.37871  ? 389 PHE B CE1 1 
ATOM   6545 C CE2 . PHE B 1 389 ? -54.07900 -30.48300 -45.04900 1.000 60.46220  ? 389 PHE B CE2 1 
ATOM   6546 C CZ  . PHE B 1 389 ? -53.33900 -31.55700 -44.61400 1.000 63.27031  ? 389 PHE B CZ  1 
ATOM   6547 N N   . HIS B 1 390 ? -53.38000 -27.91900 -41.67600 1.000 48.53433  ? 390 HIS B N   1 
ATOM   6548 C CA  . HIS B 1 390 ? -52.48600 -26.91000 -42.23400 1.000 48.58115  ? 390 HIS B CA  1 
ATOM   6549 C C   . HIS B 1 390 ? -51.34500 -27.56900 -42.99400 1.000 47.85928  ? 390 HIS B C   1 
ATOM   6550 O O   . HIS B 1 390 ? -50.85600 -28.63700 -42.61100 1.000 52.13808  ? 390 HIS B O   1 
ATOM   6551 C CB  . HIS B 1 390 ? -51.91500 -25.97400 -41.14300 1.000 46.41859  ? 390 HIS B CB  1 
ATOM   6552 C CG  . HIS B 1 390 ? -50.76200 -26.54800 -40.36900 1.000 49.16262  ? 390 HIS B CG  1 
ATOM   6553 N ND1 . HIS B 1 390 ? -49.49300 -26.67800 -40.89700 1.000 52.60332  ? 390 HIS B ND1 1 
ATOM   6554 C CD2 . HIS B 1 390 ? -50.67800 -26.98800 -39.09000 1.000 46.39948  ? 390 HIS B CD2 1 
ATOM   6555 C CE1 . HIS B 1 390 ? -48.68600 -27.19500 -39.98700 1.000 46.72428  ? 390 HIS B CE1 1 
ATOM   6556 N NE2 . HIS B 1 390 ? -49.38000 -27.39000 -38.88100 1.000 45.09620  ? 390 HIS B NE2 1 
ATOM   6557 N N   . THR B 1 391 ? -50.91600 -26.91200 -44.07000 1.000 43.88854  ? 391 THR B N   1 
ATOM   6558 C CA  . THR B 1 391 ? -49.74900 -27.35800 -44.82100 1.000 47.47948  ? 391 THR B CA  1 
ATOM   6559 C C   . THR B 1 391 ? -49.14900 -26.18300 -45.57200 1.000 48.23360  ? 391 THR B C   1 
ATOM   6560 O O   . THR B 1 391 ? -49.83700 -25.20000 -45.88200 1.000 49.48832  ? 391 THR B O   1 
ATOM   6561 C CB  . THR B 1 391 ? -50.07800 -28.46400 -45.82800 1.000 49.73167  ? 391 THR B CB  1 
ATOM   6562 O OG1 . THR B 1 391 ? -48.89500 -28.76800 -46.58400 1.000 44.11040  ? 391 THR B OG1 1 
ATOM   6563 C CG2 . THR B 1 391 ? -51.20000 -28.01700 -46.79100 1.000 42.60859  ? 391 THR B CG2 1 
ATOM   6564 N N   . ASP B 1 392 ? -47.85900 -26.32300 -45.89500 1.000 41.21474  ? 392 ASP B N   1 
ATOM   6565 C CA  . ASP B 1 392 ? -47.15100 -25.33100 -46.68900 1.000 45.57052  ? 392 ASP B CA  1 
ATOM   6566 C C   . ASP B 1 392 ? -46.88800 -25.75600 -48.13200 1.000 44.24549  ? 392 ASP B C   1 
ATOM   6567 O O   . ASP B 1 392 ? -46.75000 -24.88400 -48.99200 1.000 50.72115  ? 392 ASP B O   1 
ATOM   6568 C CB  . ASP B 1 392 ? -45.82000 -24.94200 -46.01800 1.000 50.64222  ? 392 ASP B CB  1 
ATOM   6569 C CG  . ASP B 1 392 ? -44.87000 -26.11100 -45.85100 1.000 51.35965  ? 392 ASP B CG  1 
ATOM   6570 O OD1 . ASP B 1 392 ? -45.28300 -27.26900 -46.04800 1.000 56.79041  ? 392 ASP B OD1 1 
ATOM   6571 O OD2 . ASP B 1 392 ? -43.69300 -25.86500 -45.52900 1.000 51.66010  ? 392 ASP B OD2 1 
ATOM   6572 N N   . ARG B 1 393 ? -46.83600 -27.04600 -48.43400 1.000 44.06936  ? 393 ARG B N   1 
ATOM   6573 C CA  . ARG B 1 393 ? -46.78000 -27.49600 -49.82100 1.000 49.33327  ? 393 ARG B CA  1 
ATOM   6574 C C   . ARG B 1 393 ? -48.06000 -28.26500 -50.14700 1.000 42.11213  ? 393 ARG B C   1 
ATOM   6575 O O   . ARG B 1 393 ? -48.07100 -29.49200 -50.24800 1.000 43.83180  ? 393 ARG B O   1 
ATOM   6576 C CB  . ARG B 1 393 ? -45.49800 -28.33400 -50.07100 1.000 47.28412  ? 393 ARG B CB  1 
ATOM   6577 C CG  . ARG B 1 393 ? -45.26400 -29.45900 -49.08600 1.000 56.45758  ? 393 ARG B CG  1 
ATOM   6578 C CD  . ARG B 1 393 ? -43.78400 -29.62600 -48.82400 1.000 61.75527  ? 393 ARG B CD  1 
ATOM   6579 N NE  . ARG B 1 393 ? -43.35700 -28.86000 -47.66000 1.000 59.36255  ? 393 ARG B NE  1 
ATOM   6580 C CZ  . ARG B 1 393 ? -42.14000 -28.35400 -47.51100 1.000 67.82681  ? 393 ARG B CZ  1 
ATOM   6581 N NH1 . ARG B 1 393 ? -41.21400 -28.48800 -48.45200 1.000 66.55571  ? 393 ARG B NH1 1 
ATOM   6582 N NH2 . ARG B 1 393 ? -41.84800 -27.68300 -46.39900 1.000 65.64183  ? 393 ARG B NH2 1 
ATOM   6583 N N   . LEU B 1 394 ? -49.15800 -27.51600 -50.30500 1.000 37.34505  ? 394 LEU B N   1 
ATOM   6584 C CA  . LEU B 1 394 ? -50.44200 -28.13100 -50.62700 1.000 40.68101  ? 394 LEU B CA  1 
ATOM   6585 C C   . LEU B 1 394 ? -50.31200 -29.17600 -51.72500 1.000 49.31039  ? 394 LEU B C   1 
ATOM   6586 O O   . LEU B 1 394 ? -50.79300 -30.30200 -51.57500 1.000 52.86465  ? 394 LEU B O   1 
ATOM   6587 C CB  . LEU B 1 394 ? -51.46600 -27.07400 -51.05500 1.000 40.77804  ? 394 LEU B CB  1 
ATOM   6588 C CG  . LEU B 1 394 ? -52.83000 -27.70800 -51.39900 1.000 44.55708  ? 394 LEU B CG  1 
ATOM   6589 C CD1 . LEU B 1 394 ? -53.26700 -28.60700 -50.24000 1.000 49.24123  ? 394 LEU B CD1 1 
ATOM   6590 C CD2 . LEU B 1 394 ? -53.92800 -26.68500 -51.72300 1.000 36.95611  ? 394 LEU B CD2 1 
ATOM   6591 N N   . GLY B 1 395 ? -49.65900 -28.81500 -52.83900 1.000 52.81612  ? 395 GLY B N   1 
ATOM   6592 C CA  . GLY B 1 395 ? -49.65700 -29.67300 -54.01900 1.000 49.04801  ? 395 GLY B CA  1 
ATOM   6593 C C   . GLY B 1 395 ? -49.08000 -31.05300 -53.77400 1.000 55.65284  ? 395 GLY B C   1 
ATOM   6594 O O   . GLY B 1 395 ? -49.47800 -32.02100 -54.43200 1.000 57.77504  ? 395 GLY B O   1 
ATOM   6595 N N   . THR B 1 396 ? -48.13100 -31.16200 -52.83700 1.000 55.48878  ? 396 THR B N   1 
ATOM   6596 C CA  . THR B 1 396 ? -47.67200 -32.46400 -52.36200 1.000 49.33476  ? 396 THR B CA  1 
ATOM   6597 C C   . THR B 1 396 ? -48.83500 -33.30700 -51.84600 1.000 56.58041  ? 396 THR B C   1 
ATOM   6598 O O   . THR B 1 396 ? -48.86800 -34.52600 -52.04100 1.000 58.50891  ? 396 THR B O   1 
ATOM   6599 C CB  . THR B 1 396 ? -46.62200 -32.26000 -51.26400 1.000 54.29216  ? 396 THR B CB  1 
ATOM   6600 O OG1 . THR B 1 396 ? -45.30900 -32.41300 -51.81400 1.000 66.11874  ? 396 THR B OG1 1 
ATOM   6601 C CG2 . THR B 1 396 ? -46.81500 -33.23400 -50.09200 1.000 59.14916  ? 396 THR B CG2 1 
ATOM   6602 N N   . VAL B 1 397 ? -49.81100 -32.66700 -51.20400 1.000 58.55103  ? 397 VAL B N   1 
ATOM   6603 C CA  . VAL B 1 397 ? -50.91200 -33.35600 -50.54500 1.000 53.86962  ? 397 VAL B CA  1 
ATOM   6604 C C   . VAL B 1 397 ? -52.16200 -33.44000 -51.42200 1.000 58.17660  ? 397 VAL B C   1 
ATOM   6605 O O   . VAL B 1 397 ? -53.10200 -34.17800 -51.07800 1.000 60.41261  ? 397 VAL B O   1 
ATOM   6606 C CB  . VAL B 1 397 ? -51.23000 -32.64900 -49.20600 1.000 52.33931  ? 397 VAL B CB  1 
ATOM   6607 C CG1 . VAL B 1 397 ? -52.17500 -33.45400 -48.34200 1.000 61.74902  ? 397 VAL B CG1 1 
ATOM   6608 C CG2 . VAL B 1 397 ? -49.94800 -32.35300 -48.44300 1.000 54.41664  ? 397 VAL B CG2 1 
ATOM   6609 N N   . TYR B 1 398 ? -52.19700 -32.73700 -52.55600 1.000 56.37997  ? 398 TYR B N   1 
ATOM   6610 C CA  . TYR B 1 398 ? -53.43900 -32.58000 -53.31000 1.000 56.09556  ? 398 TYR B CA  1 
ATOM   6611 C C   . TYR B 1 398 ? -53.15600 -31.95800 -54.67800 1.000 59.13468  ? 398 TYR B C   1 
ATOM   6612 O O   . TYR B 1 398 ? -53.31100 -30.74100 -54.84600 1.000 61.25006  ? 398 TYR B O   1 
ATOM   6613 C CB  . TYR B 1 398 ? -54.42000 -31.72400 -52.49700 1.000 53.19696  ? 398 TYR B CB  1 
ATOM   6614 C CG  . TYR B 1 398 ? -55.75100 -31.40600 -53.15600 1.000 57.37029  ? 398 TYR B CG  1 
ATOM   6615 C CD1 . TYR B 1 398 ? -56.79000 -32.33300 -53.17000 1.000 56.27559  ? 398 TYR B CD1 1 
ATOM   6616 C CD2 . TYR B 1 398 ? -55.98100 -30.16100 -53.72700 1.000 55.21660  ? 398 TYR B CD2 1 
ATOM   6617 C CE1 . TYR B 1 398 ? -58.01000 -32.03200 -53.75900 1.000 58.73508  ? 398 TYR B CE1 1 
ATOM   6618 C CE2 . TYR B 1 398 ? -57.19000 -29.85100 -54.31800 1.000 61.55210  ? 398 TYR B CE2 1 
ATOM   6619 C CZ  . TYR B 1 398 ? -58.20400 -30.78600 -54.32900 1.000 64.00317  ? 398 TYR B CZ  1 
ATOM   6620 O OH  . TYR B 1 398 ? -59.40500 -30.46000 -54.92000 1.000 62.74862  ? 398 TYR B OH  1 
ATOM   6621 N N   . PRO B 1 399 ? -52.74400 -32.74400 -55.67400 1.000 60.18500  ? 399 PRO B N   1 
ATOM   6622 C CA  . PRO B 1 399 ? -52.28000 -32.15800 -56.95100 1.000 62.38273  ? 399 PRO B CA  1 
ATOM   6623 C C   . PRO B 1 399 ? -53.39700 -31.60600 -57.83300 1.000 58.67927  ? 399 PRO B C   1 
ATOM   6624 O O   . PRO B 1 399 ? -53.09300 -30.97900 -58.85900 1.000 54.73458  ? 399 PRO B O   1 
ATOM   6625 C CB  . PRO B 1 399 ? -51.55600 -33.33400 -57.63400 1.000 60.12363  ? 399 PRO B CB  1 
ATOM   6626 C CG  . PRO B 1 399 ? -51.20500 -34.26100 -56.52900 1.000 58.52512  ? 399 PRO B CG  1 
ATOM   6627 C CD  . PRO B 1 399 ? -52.36200 -34.16300 -55.57000 1.000 59.13909  ? 399 PRO B CD  1 
ATOM   6628 N N   . PRO B 1 400 ? -54.70900 -31.80000 -57.51200 1.000 59.16326  ? 400 PRO B N   1 
ATOM   6629 C CA  . PRO B 1 400 ? -55.71900 -30.98200 -58.21000 1.000 56.44213  ? 400 PRO B CA  1 
ATOM   6630 C C   . PRO B 1 400 ? -55.43200 -29.48200 -58.18600 1.000 64.12637  ? 400 PRO B C   1 
ATOM   6631 O O   . PRO B 1 400 ? -56.01300 -28.72800 -58.98100 1.000 57.97682  ? 400 PRO B O   1 
ATOM   6632 C CB  . PRO B 1 400 ? -57.00900 -31.31100 -57.45300 1.000 56.50059  ? 400 PRO B CB  1 
ATOM   6633 C CG  . PRO B 1 400 ? -56.83800 -32.73600 -57.09400 1.000 61.57819  ? 400 PRO B CG  1 
ATOM   6634 C CD  . PRO B 1 400 ? -55.34900 -32.99400 -56.91600 1.000 57.63772  ? 400 PRO B CD  1 
ATOM   6635 N N   . LEU B 1 401 ? -54.53900 -29.04200 -57.27900 1.000 57.24831  ? 401 LEU B N   1 
ATOM   6636 C CA  . LEU B 1 401 ? -54.15600 -27.64000 -57.15100 1.000 54.76964  ? 401 LEU B CA  1 
ATOM   6637 C C   . LEU B 1 401 ? -52.65600 -27.40900 -57.28000 1.000 52.03380  ? 401 LEU B C   1 
ATOM   6638 O O   . LEU B 1 401 ? -52.19500 -26.29900 -57.00200 1.000 51.50298  ? 401 LEU B O   1 
ATOM   6639 C CB  . LEU B 1 401 ? -54.62000 -27.05400 -55.81000 1.000 48.07980  ? 401 LEU B CB  1 
ATOM   6640 C CG  . LEU B 1 401 ? -56.04100 -26.50800 -55.69400 1.000 57.99595  ? 401 LEU B CG  1 
ATOM   6641 C CD1 . LEU B 1 401 ? -56.09700 -25.49200 -54.55600 1.000 57.48498  ? 401 LEU B CD1 1 
ATOM   6642 C CD2 . LEU B 1 401 ? -56.52600 -25.90100 -57.01300 1.000 55.26590  ? 401 LEU B CD2 1 
ATOM   6643 N N   . ALA B 1 402 ? -51.87900 -28.41400 -57.68100 1.000 54.84391  ? 402 ALA B N   1 
ATOM   6644 C CA  . ALA B 1 402 ? -50.43200 -28.24100 -57.71300 1.000 50.77782  ? 402 ALA B CA  1 
ATOM   6645 C C   . ALA B 1 402 ? -49.99400 -27.12200 -58.65400 1.000 48.39233  ? 402 ALA B C   1 
ATOM   6646 O O   . ALA B 1 402 ? -48.86200 -26.64400 -58.53600 1.000 55.90749  ? 402 ALA B O   1 
ATOM   6647 C CB  . ALA B 1 402 ? -49.75300 -29.55400 -58.10900 1.000 49.88564  ? 402 ALA B CB  1 
ATOM   6648 N N   . ALA B 1 403 ? -50.84900 -26.69300 -59.58700 1.000 49.54978  ? 403 ALA B N   1 
ATOM   6649 C CA  . ALA B 1 403 ? -50.49200 -25.61500 -60.51000 1.000 49.66701  ? 403 ALA B CA  1 
ATOM   6650 C C   . ALA B 1 403 ? -50.87700 -24.23500 -59.98800 1.000 50.48823  ? 403 ALA B C   1 
ATOM   6651 O O   . ALA B 1 403 ? -50.69100 -23.23500 -60.69700 1.000 46.21792  ? 403 ALA B O   1 
ATOM   6652 C CB  . ALA B 1 403 ? -51.13900 -25.83500 -61.88400 1.000 45.04636  ? 403 ALA B CB  1 
ATOM   6653 N N   . ARG B 1 404 ? -51.42400 -24.15100 -58.77900 1.000 47.61436  ? 404 ARG B N   1 
ATOM   6654 C CA  . ARG B 1 404 ? -51.91000 -22.89000 -58.24500 1.000 48.56862  ? 404 ARG B CA  1 
ATOM   6655 C C   . ARG B 1 404 ? -51.06400 -22.44400 -57.06300 1.000 40.46460  ? 404 ARG B C   1 
ATOM   6656 O O   . ARG B 1 404 ? -51.55200 -21.79000 -56.14400 1.000 42.89550  ? 404 ARG B O   1 
ATOM   6657 C CB  . ARG B 1 404 ? -53.38300 -22.98100 -57.86100 1.000 48.37566  ? 404 ARG B CB  1 
ATOM   6658 C CG  . ARG B 1 404 ? -54.32800 -23.27600 -59.02500 1.000 49.63971  ? 404 ARG B CG  1 
ATOM   6659 C CD  . ARG B 1 404 ? -54.07200 -22.39600 -60.24100 1.000 49.06122  ? 404 ARG B CD  1 
ATOM   6660 N NE  . ARG B 1 404 ? -54.11400 -20.96300 -59.95500 1.000 55.35104  ? 404 ARG B NE  1 
ATOM   6661 C CZ  . ARG B 1 404 ? -55.22300 -20.26500 -59.73400 1.000 55.88418  ? 404 ARG B CZ  1 
ATOM   6662 N NH1 . ARG B 1 404 ? -56.41000 -20.84300 -59.70400 1.000 62.53063  ? 404 ARG B NH1 1 
ATOM   6663 N NH2 . ARG B 1 404 ? -55.13600 -18.95200 -59.53000 1.000 59.19656  ? 404 ARG B NH2 1 
ATOM   6664 N N   . ALA B 1 405 ? -49.77400 -22.77300 -57.09500 1.000 38.32831  ? 405 ALA B N   1 
ATOM   6665 C CA  . ALA B 1 405 ? -48.83600 -22.18800 -56.15100 1.000 35.76261  ? 405 ALA B CA  1 
ATOM   6666 C C   . ALA B 1 405 ? -48.72100 -20.67600 -56.28200 1.000 41.81273  ? 405 ALA B C   1 
ATOM   6667 O O   . ALA B 1 405 ? -47.92700 -20.07300 -55.54000 1.000 38.73288  ? 405 ALA B O   1 
ATOM   6668 C CB  . ALA B 1 405 ? -47.45500 -22.81400 -56.31800 1.000 43.92971  ? 405 ALA B CB  1 
ATOM   6669 N N   . ASP B 1 406 ? -49.48200 -20.04600 -57.19100 1.000 39.08883  ? 406 ASP B N   1 
ATOM   6670 C CA  . ASP B 1 406 ? -49.55700 -18.59200 -57.20700 1.000 35.96787  ? 406 ASP B CA  1 
ATOM   6671 C C   . ASP B 1 406 ? -50.49600 -18.05300 -56.13200 1.000 39.49179  ? 406 ASP B C   1 
ATOM   6672 O O   . ASP B 1 406 ? -50.45700 -16.85400 -55.83300 1.000 36.82558  ? 406 ASP B O   1 
ATOM   6673 C CB  . ASP B 1 406 ? -50.00200 -18.08200 -58.58200 1.000 32.07298  ? 406 ASP B CB  1 
ATOM   6674 C CG  . ASP B 1 406 ? -51.28400 -18.73800 -59.06600 1.000 42.96877  ? 406 ASP B CG  1 
ATOM   6675 O OD1 . ASP B 1 406 ? -51.31200 -19.97800 -59.10800 1.000 44.13155  ? 406 ASP B OD1 1 
ATOM   6676 O OD2 . ASP B 1 406 ? -52.26100 -18.03400 -59.40900 1.000 45.98256  ? 406 ASP B OD2 1 
ATOM   6677 N N   . VAL B 1 407 ? -51.32700 -18.89900 -55.52900 1.000 33.41145  ? 407 VAL B N   1 
ATOM   6678 C CA  . VAL B 1 407 ? -52.34300 -18.38900 -54.61800 1.000 36.79377  ? 407 VAL B CA  1 
ATOM   6679 C C   . VAL B 1 407 ? -52.58000 -19.38000 -53.48700 1.000 38.73036  ? 407 VAL B C   1 
ATOM   6680 O O   . VAL B 1 407 ? -53.27200 -19.06900 -52.51000 1.000 42.44146  ? 407 VAL B O   1 
ATOM   6681 C CB  . VAL B 1 407 ? -53.66800 -18.09500 -55.35200 1.000 40.13385  ? 407 VAL B CB  1 
ATOM   6682 C CG1 . VAL B 1 407 ? -53.50200 -16.97300 -56.38600 1.000 34.09674  ? 407 VAL B CG1 1 
ATOM   6683 C CG2 . VAL B 1 407 ? -54.21000 -19.37200 -55.99100 1.000 43.67391  ? 407 VAL B CG2 1 
ATOM   6684 N N   . ALA B 1 408 ? -52.03200 -20.58100 -53.60300 1.000 35.41639  ? 408 ALA B N   1 
ATOM   6685 C CA  . ALA B 1 408 ? -52.42800 -21.64600 -52.68700 1.000 37.54447  ? 408 ALA B CA  1 
ATOM   6686 C C   . ALA B 1 408 ? -51.35200 -22.72200 -52.59800 1.000 33.81504  ? 408 ALA B C   1 
ATOM   6687 O O   . ALA B 1 408 ? -51.63300 -23.91400 -52.69200 1.000 34.34101  ? 408 ALA B O   1 
ATOM   6688 C CB  . ALA B 1 408 ? -53.76800 -22.25200 -53.10600 1.000 39.83205  ? 408 ALA B CB  1 
ATOM   6689 N N   . ALA B 1 409 ? -50.09900 -22.30900 -52.41600 1.000 34.35137  ? 409 ALA B N   1 
ATOM   6690 C CA  . ALA B 1 409 ? -49.06900 -23.26500 -52.02700 1.000 30.81803  ? 409 ALA B CA  1 
ATOM   6691 C C   . ALA B 1 409 ? -49.32600 -23.78100 -50.61800 1.000 36.96374  ? 409 ALA B C   1 
ATOM   6692 O O   . ALA B 1 409 ? -49.14000 -24.97200 -50.33900 1.000 42.73130  ? 409 ALA B O   1 
ATOM   6693 C CB  . ALA B 1 409 ? -47.68200 -22.62300 -52.12100 1.000 37.85171  ? 409 ALA B CB  1 
ATOM   6694 N N   . GLY B 1 410 ? -49.77800 -22.90300 -49.72600 1.000 38.49286  ? 410 GLY B N   1 
ATOM   6695 C CA  . GLY B 1 410 ? -50.09500 -23.28200 -48.36200 1.000 42.59737  ? 410 GLY B CA  1 
ATOM   6696 C C   . GLY B 1 410 ? -51.53300 -22.95200 -48.00100 1.000 40.09663  ? 410 GLY B C   1 
ATOM   6697 O O   . GLY B 1 410 ? -52.11200 -21.97800 -48.49700 1.000 35.74101  ? 410 GLY B O   1 
ATOM   6698 N N   . ILE B 1 411 ? -52.10500 -23.77000 -47.11600 1.000 41.09197  ? 411 ILE B N   1 
ATOM   6699 C CA  . ILE B 1 411 ? -53.47100 -23.57500 -46.64500 1.000 38.27088  ? 411 ILE B CA  1 
ATOM   6700 C C   . ILE B 1 411 ? -53.54200 -23.82300 -45.14700 1.000 40.91376  ? 411 ILE B C   1 
ATOM   6701 O O   . ILE B 1 411 ? -52.76600 -24.60400 -44.58900 1.000 40.65519  ? 411 ILE B O   1 
ATOM   6702 C CB  . ILE B 1 411 ? -54.47400 -24.49200 -47.36300 1.000 40.79642  ? 411 ILE B CB  1 
ATOM   6703 C CG1 . ILE B 1 411 ? -54.02700 -25.94900 -47.25300 1.000 48.31448  ? 411 ILE B CG1 1 
ATOM   6704 C CG2 . ILE B 1 411 ? -54.65800 -24.06300 -48.82000 1.000 44.49561  ? 411 ILE B CG2 1 
ATOM   6705 C CD1 . ILE B 1 411 ? -55.17100 -26.95500 -47.41600 1.000 51.38931  ? 411 ILE B CD1 1 
ATOM   6706 N N   . LEU B 1 412 ? -54.48700 -23.13700 -44.49900 1.000 38.85137  ? 412 LEU B N   1 
ATOM   6707 C CA  . LEU B 1 412 ? -54.84500 -23.36600 -43.10200 1.000 38.30559  ? 412 LEU B CA  1 
ATOM   6708 C C   . LEU B 1 412 ? -56.36500 -23.33900 -43.03100 1.000 45.16416  ? 412 LEU B C   1 
ATOM   6709 O O   . LEU B 1 412 ? -56.98100 -22.27400 -43.17000 1.000 43.52175  ? 412 LEU B O   1 
ATOM   6710 C CB  . LEU B 1 412 ? -54.23200 -22.30800 -42.17600 1.000 39.31796  ? 412 LEU B CB  1 
ATOM   6711 C CG  . LEU B 1 412 ? -54.15600 -22.56000 -40.66100 1.000 43.61948  ? 412 LEU B CG  1 
ATOM   6712 C CD1 . LEU B 1 412 ? -53.40500 -21.44000 -39.96800 1.000 44.07935  ? 412 LEU B CD1 1 
ATOM   6713 C CD2 . LEU B 1 412 ? -55.51400 -22.73300 -40.01100 1.000 43.29642  ? 412 LEU B CD2 1 
ATOM   6714 N N   . ALA B 1 413 ? -56.97200 -24.50300 -42.81300 1.000 51.40990  ? 413 ALA B N   1 
ATOM   6715 C CA  . ALA B 1 413 ? -58.42000 -24.62300 -42.68200 1.000 56.36859  ? 413 ALA B CA  1 
ATOM   6716 C C   . ALA B 1 413 ? -58.77400 -25.09100 -41.27300 1.000 52.64501  ? 413 ALA B C   1 
ATOM   6717 O O   . ALA B 1 413 ? -58.19000 -26.06100 -40.77000 1.000 46.40500  ? 413 ALA B O   1 
ATOM   6718 C CB  . ALA B 1 413 ? -58.99100 -25.59100 -43.72600 1.000 52.14683  ? 413 ALA B CB  1 
ATOM   6719 N N   . VAL B 1 414 ? -59.71800 -24.38900 -40.63800 1.000 47.71084  ? 414 VAL B N   1 
ATOM   6720 C CA  . VAL B 1 414 ? -60.34000 -24.83200 -39.39200 1.000 56.86688  ? 414 VAL B CA  1 
ATOM   6721 C C   . VAL B 1 414 ? -61.74300 -25.33800 -39.70500 1.000 55.19970  ? 414 VAL B C   1 
ATOM   6722 O O   . VAL B 1 414 ? -62.48200 -24.71900 -40.48100 1.000 50.57341  ? 414 VAL B O   1 
ATOM   6723 C CB  . VAL B 1 414 ? -60.39500 -23.72500 -38.31100 1.000 52.28256  ? 414 VAL B CB  1 
ATOM   6724 C CG1 . VAL B 1 414 ? -58.99500 -23.42600 -37.76600 1.000 47.32862  ? 414 VAL B CG1 1 
ATOM   6725 C CG2 . VAL B 1 414 ? -61.08500 -22.45900 -38.83400 1.000 45.95250  ? 414 VAL B CG2 1 
ATOM   6726 N N   . ARG B 1 415 ? -62.11000 -26.46500 -39.09500 1.000 60.07689  ? 415 ARG B N   1 
ATOM   6727 C CA  . ARG B 1 415 ? -63.46300 -26.99400 -39.21300 1.000 60.12043  ? 415 ARG B CA  1 
ATOM   6728 C C   . ARG B 1 415 ? -64.37800 -26.20500 -38.28500 1.000 61.35431  ? 415 ARG B C   1 
ATOM   6729 O O   . ARG B 1 415 ? -64.16100 -26.18400 -37.07000 1.000 63.52393  ? 415 ARG B O   1 
ATOM   6730 C CB  . ARG B 1 415 ? -63.48700 -28.48700 -38.88100 1.000 62.41339  ? 415 ARG B CB  1 
ATOM   6731 C CG  . ARG B 1 415 ? -64.71600 -29.21500 -39.40900 1.000 69.60669  ? 415 ARG B CG  1 
ATOM   6732 C CD  . ARG B 1 415 ? -64.39400 -30.61300 -39.92600 1.000 68.28213  ? 415 ARG B CD  1 
ATOM   6733 N NE  . ARG B 1 415 ? -63.77100 -31.43000 -38.89600 1.000 71.20459  ? 415 ARG B NE  1 
ATOM   6734 C CZ  . ARG B 1 415 ? -62.92100 -32.41900 -39.13500 1.000 69.44697  ? 415 ARG B CZ  1 
ATOM   6735 N NH1 . ARG B 1 415 ? -62.57800 -32.75700 -40.37000 1.000 64.66207  ? 415 ARG B NH1 1 
ATOM   6736 N NH2 . ARG B 1 415 ? -62.38800 -33.07300 -38.10700 1.000 67.88708  ? 415 ARG B NH2 1 
ATOM   6737 N N   . LEU B 1 416 ? -65.39100 -25.54200 -38.86200 1.000 67.46219  ? 416 LEU B N   1 
ATOM   6738 C CA  . LEU B 1 416 ? -66.29600 -24.68000 -38.10400 1.000 67.43412  ? 416 LEU B CA  1 
ATOM   6739 C C   . LEU B 1 416 ? -67.40700 -25.44100 -37.39400 1.000 74.26806  ? 416 LEU B C   1 
ATOM   6740 O O   . LEU B 1 416 ? -68.04300 -24.87400 -36.49900 1.000 77.17158  ? 416 LEU B O   1 
ATOM   6741 C CB  . LEU B 1 416 ? -66.93000 -23.63100 -39.02500 1.000 68.90279  ? 416 LEU B CB  1 
ATOM   6742 C CG  . LEU B 1 416 ? -66.04100 -22.45700 -39.45700 1.000 67.12137  ? 416 LEU B CG  1 
ATOM   6743 C CD1 . LEU B 1 416 ? -66.74800 -21.54300 -40.45800 1.000 62.14681  ? 416 LEU B CD1 1 
ATOM   6744 C CD2 . LEU B 1 416 ? -65.57800 -21.67900 -38.24000 1.000 55.01890  ? 416 LEU B CD2 1 
ATOM   6745 N N   . ALA B 1 417 ? -67.66400 -26.69000 -37.77800 1.000 78.07489  ? 417 ALA B N   1 
ATOM   6746 C CA  . ALA B 1 417 ? -68.67400 -27.55900 -37.19500 1.000 81.26043  ? 417 ALA B CA  1 
ATOM   6747 C C   . ALA B 1 417 ? -68.06400 -28.91900 -36.88900 1.000 88.50678  ? 417 ALA B C   1 
ATOM   6748 O O   . ALA B 1 417 ? -67.08600 -29.31800 -37.52700 1.000 85.13962  ? 417 ALA B O   1 
ATOM   6749 C CB  . ALA B 1 417 ? -69.87000 -27.73600 -38.14300 1.000 86.02546  ? 417 ALA B CB  1 
ATOM   6750 N N   . PRO B 1 418 ? -68.61500 -29.65700 -35.91100 1.000 95.85528  ? 418 PRO B N   1 
ATOM   6751 C CA  . PRO B 1 418 ? -68.09700 -31.00700 -35.64000 1.000 98.13696  ? 418 PRO B CA  1 
ATOM   6752 C C   . PRO B 1 418 ? -68.35600 -31.93500 -36.81700 1.000 102.97267 ? 418 PRO B C   1 
ATOM   6753 O O   . PRO B 1 418 ? -67.54500 -32.01300 -37.74900 1.000 99.56094  ? 418 PRO B O   1 
ATOM   6754 C CB  . PRO B 1 418 ? -68.87300 -31.43700 -34.39000 1.000 95.42142  ? 418 PRO B CB  1 
ATOM   6755 C CG  . PRO B 1 418 ? -70.14000 -30.64200 -34.44700 1.000 91.22191  ? 418 PRO B CG  1 
ATOM   6756 C CD  . PRO B 1 418 ? -69.75500 -29.31900 -35.04000 1.000 92.89885  ? 418 PRO B CD  1 
ATOM   6757 N N   . ALA B 1 419 ? -69.48000 -32.64800 -36.78100 1.000 99.14221  ? 419 ALA B N   1 
ATOM   6758 C CA  . ALA B 1 419 ? -70.00000 -33.22700 -38.00400 1.000 95.93981  ? 419 ALA B CA  1 
ATOM   6759 C C   . ALA B 1 419 ? -70.42000 -32.10300 -38.94600 1.000 101.26435 ? 419 ALA B C   1 
ATOM   6760 O O   . ALA B 1 419 ? -70.58800 -30.94600 -38.53600 1.000 95.23047  ? 419 ALA B O   1 
ATOM   6761 C CB  . ALA B 1 419 ? -71.17600 -34.15800 -37.71200 1.000 98.89982  ? 419 ALA B CB  1 
ATOM   6762 N N   . ALA B 1 420 ? -70.59000 -32.46800 -40.22200 1.000 109.34222 ? 420 ALA B N   1 
ATOM   6763 C CA  . ALA B 1 420 ? -70.74400 -31.55000 -41.35100 1.000 101.91921 ? 420 ALA B CA  1 
ATOM   6764 C C   . ALA B 1 420 ? -69.40800 -30.89000 -41.68600 1.000 94.86619  ? 420 ALA B C   1 
ATOM   6765 O O   . ALA B 1 420 ? -68.41100 -31.07500 -40.97500 1.000 88.18106  ? 420 ALA B O   1 
ATOM   6766 C CB  . ALA B 1 420 ? -71.82800 -30.49600 -41.08500 1.000 97.85250  ? 420 ALA B CB  1 
ATOM   6767 N N   . ALA B 1 421 ? -69.37300 -30.12700 -42.77900 1.000 92.59817  ? 421 ALA B N   1 
ATOM   6768 C CA  . ALA B 1 421 ? -68.12900 -29.59100 -43.31300 1.000 88.84568  ? 421 ALA B CA  1 
ATOM   6769 C C   . ALA B 1 421 ? -68.28900 -28.11500 -43.68800 1.000 87.99225  ? 421 ALA B C   1 
ATOM   6770 O O   . ALA B 1 421 ? -68.19100 -27.72100 -44.84800 1.000 87.79712  ? 421 ALA B O   1 
ATOM   6771 C CB  . ALA B 1 421 ? -67.65800 -30.41300 -44.51100 1.000 85.88541  ? 421 ALA B CB  1 
ATOM   6772 N N   . ARG B 1 422 ? -68.54400 -27.27800 -42.68400 1.000 87.60219  ? 422 ARG B N   1 
ATOM   6773 C CA  . ARG B 1 422 ? -68.33400 -25.84200 -42.81400 1.000 86.76374  ? 422 ARG B CA  1 
ATOM   6774 C C   . ARG B 1 422 ? -66.87600 -25.53900 -42.48800 1.000 73.17594  ? 422 ARG B C   1 
ATOM   6775 O O   . ARG B 1 422 ? -66.32200 -26.08400 -41.52900 1.000 66.54733  ? 422 ARG B O   1 
ATOM   6776 C CB  . ARG B 1 422 ? -69.25100 -25.05600 -41.87500 1.000 84.73978  ? 422 ARG B CB  1 
ATOM   6777 C CG  . ARG B 1 422 ? -70.58800 -25.71200 -41.60400 1.000 91.09706  ? 422 ARG B CG  1 
ATOM   6778 C CD  . ARG B 1 422 ? -71.54000 -25.60300 -42.78300 1.000 95.88655  ? 422 ARG B CD  1 
ATOM   6779 N NE  . ARG B 1 422 ? -72.80500 -26.25100 -42.45500 1.000 107.44055 ? 422 ARG B NE  1 
ATOM   6780 C CZ  . ARG B 1 422 ? -73.08500 -27.52100 -42.71300 1.000 108.12480 ? 422 ARG B CZ  1 
ATOM   6781 N NH1 . ARG B 1 422 ? -72.24500 -28.29100 -43.38600 1.000 105.96712 ? 422 ARG B NH1 1 
ATOM   6782 N NH2 . ARG B 1 422 ? -74.23800 -28.03300 -42.28500 1.000 113.84238 ? 422 ARG B NH2 1 
ATOM   6783 N N   . PHE B 1 423 ? -66.25200 -24.67900 -43.29200 1.000 72.58320  ? 423 PHE B N   1 
ATOM   6784 C CA  . PHE B 1 423 ? -64.84200 -24.37400 -43.10500 1.000 63.52051  ? 423 PHE B CA  1 
ATOM   6785 C C   . PHE B 1 423 ? -64.57600 -22.89400 -43.32400 1.000 63.30169  ? 423 PHE B C   1 
ATOM   6786 O O   . PHE B 1 423 ? -65.29700 -22.21100 -44.05700 1.000 63.41601  ? 423 PHE B O   1 
ATOM   6787 C CB  . PHE B 1 423 ? -63.94300 -25.16900 -44.05500 1.000 59.98703  ? 423 PHE B CB  1 
ATOM   6788 C CG  . PHE B 1 423 ? -63.81700 -26.63100 -43.71400 1.000 72.71260  ? 423 PHE B CG  1 
ATOM   6789 C CD1 . PHE B 1 423 ? -64.73600 -27.55300 -44.19500 1.000 76.10954  ? 423 PHE B CD1 1 
ATOM   6790 C CD2 . PHE B 1 423 ? -62.75500 -27.09000 -42.94300 1.000 69.45676  ? 423 PHE B CD2 1 
ATOM   6791 C CE1 . PHE B 1 423 ? -64.61100 -28.90000 -43.89000 1.000 76.44956  ? 423 PHE B CE1 1 
ATOM   6792 C CE2 . PHE B 1 423 ? -62.62300 -28.44100 -42.63700 1.000 66.54587  ? 423 PHE B CE2 1 
ATOM   6793 C CZ  . PHE B 1 423 ? -63.55400 -29.34300 -43.10900 1.000 71.75704  ? 423 PHE B CZ  1 
ATOM   6794 N N   . ALA B 1 424 ? -63.54400 -22.40800 -42.64100 1.000 61.62630  ? 424 ALA B N   1 
ATOM   6795 C CA  . ALA B 1 424 ? -62.77300 -21.24900 -43.05900 1.000 56.92017  ? 424 ALA B CA  1 
ATOM   6796 C C   . ALA B 1 424 ? -61.41300 -21.77100 -43.49300 1.000 51.93023  ? 424 ALA B C   1 
ATOM   6797 O O   . ALA B 1 424 ? -60.82900 -22.63000 -42.82100 1.000 48.12504  ? 424 ALA B O   1 
ATOM   6798 C CB  . ALA B 1 424 ? -62.61700 -20.22200 -41.93600 1.000 48.38830  ? 424 ALA B CB  1 
ATOM   6799 N N   . ILE B 1 425 ? -60.94000 -21.30800 -44.64800 1.000 47.57834  ? 425 ILE B N   1 
ATOM   6800 C CA  . ILE B 1 425 ? -59.65500 -21.74500 -45.18100 1.000 47.08648  ? 425 ILE B CA  1 
ATOM   6801 C C   . ILE B 1 425 ? -58.86400 -20.50500 -45.55300 1.000 46.02525  ? 425 ILE B C   1 
ATOM   6802 O O   . ILE B 1 425 ? -59.33800 -19.67900 -46.34400 1.000 44.01155  ? 425 ILE B O   1 
ATOM   6803 C CB  . ILE B 1 425 ? -59.80400 -22.68100 -46.39600 1.000 47.67205  ? 425 ILE B CB  1 
ATOM   6804 C CG1 . ILE B 1 425 ? -60.90700 -23.70700 -46.14500 1.000 49.60160  ? 425 ILE B CG1 1 
ATOM   6805 C CG2 . ILE B 1 425 ? -58.47900 -23.41200 -46.68700 1.000 46.76974  ? 425 ILE B CG2 1 
ATOM   6806 C CD1 . ILE B 1 425 ? -61.10900 -24.67500 -47.25300 1.000 47.31368  ? 425 ILE B CD1 1 
ATOM   6807 N N   . TRP B 1 426 ? -57.67900 -20.35800 -44.96500 1.000 45.10541  ? 426 TRP B N   1 
ATOM   6808 C CA  . TRP B 1 426 ? -56.74300 -19.32500 -45.38000 1.000 41.08544  ? 426 TRP B CA  1 
ATOM   6809 C C   . TRP B 1 426 ? -55.78100 -19.88700 -46.42000 1.000 37.37228  ? 426 TRP B C   1 
ATOM   6810 O O   . TRP B 1 426 ? -55.40400 -21.05800 -46.36100 1.000 38.83911  ? 426 TRP B O   1 
ATOM   6811 C CB  . TRP B 1 426 ? -55.98900 -18.77900 -44.17200 1.000 36.86305  ? 426 TRP B CB  1 
ATOM   6812 C CG  . TRP B 1 426 ? -56.85200 -17.93000 -43.31900 1.000 38.62494  ? 426 TRP B CG  1 
ATOM   6813 C CD1 . TRP B 1 426 ? -57.03800 -16.57700 -43.42100 1.000 41.61577  ? 426 TRP B CD1 1 
ATOM   6814 C CD2 . TRP B 1 426 ? -57.67100 -18.36800 -42.22700 1.000 41.49881  ? 426 TRP B CD2 1 
ATOM   6815 N NE1 . TRP B 1 426 ? -57.91800 -16.14200 -42.44600 1.000 40.33127  ? 426 TRP B NE1 1 
ATOM   6816 C CE2 . TRP B 1 426 ? -58.32000 -17.22300 -41.70200 1.000 42.40964  ? 426 TRP B CE2 1 
ATOM   6817 C CE3 . TRP B 1 426 ? -57.91400 -19.61500 -41.63100 1.000 46.58509  ? 426 TRP B CE3 1 
ATOM   6818 C CZ2 . TRP B 1 426 ? -59.19600 -17.29200 -40.61100 1.000 39.77245  ? 426 TRP B CZ2 1 
ATOM   6819 C CZ3 . TRP B 1 426 ? -58.79300 -19.67800 -40.53800 1.000 45.66827  ? 426 TRP B CZ3 1 
ATOM   6820 C CH2 . TRP B 1 426 ? -59.41600 -18.52200 -40.04400 1.000 36.22441  ? 426 TRP B CH2 1 
ATOM   6821 N N   . PHE B 1 427 ? -55.41800 -19.05700 -47.39300 1.000 36.71441  ? 427 PHE B N   1 
ATOM   6822 C CA  . PHE B 1 427 ? -54.53300 -19.45800 -48.48300 1.000 39.75517  ? 427 PHE B CA  1 
ATOM   6823 C C   . PHE B 1 427 ? -53.24100 -18.65500 -48.44500 1.000 32.65700  ? 427 PHE B C   1 
ATOM   6824 O O   . PHE B 1 427 ? -53.24700 -17.46000 -48.12800 1.000 30.75920  ? 427 PHE B O   1 
ATOM   6825 C CB  . PHE B 1 427 ? -55.20100 -19.25400 -49.85000 1.000 40.02992  ? 427 PHE B CB  1 
ATOM   6826 C CG  . PHE B 1 427 ? -56.34800 -20.17200 -50.10100 1.000 39.45468  ? 427 PHE B CG  1 
ATOM   6827 C CD1 . PHE B 1 427 ? -56.12300 -21.48500 -50.47400 1.000 38.16948  ? 427 PHE B CD1 1 
ATOM   6828 C CD2 . PHE B 1 427 ? -57.65500 -19.72600 -49.96700 1.000 45.15329  ? 427 PHE B CD2 1 
ATOM   6829 C CE1 . PHE B 1 427 ? -57.17700 -22.34800 -50.69900 1.000 42.83123  ? 427 PHE B CE1 1 
ATOM   6830 C CE2 . PHE B 1 427 ? -58.72200 -20.58600 -50.20100 1.000 47.02033  ? 427 PHE B CE2 1 
ATOM   6831 C CZ  . PHE B 1 427 ? -58.48100 -21.90000 -50.56500 1.000 44.81526  ? 427 PHE B CZ  1 
ATOM   6832 N N   . ARG B 1 428 ? -52.13700 -19.31100 -48.78700 1.000 28.64955  ? 428 ARG B N   1 
ATOM   6833 C CA  . ARG B 1 428 ? -50.89200 -18.59400 -48.98000 1.000 32.76613  ? 428 ARG B CA  1 
ATOM   6834 C C   . ARG B 1 428 ? -50.29400 -18.97300 -50.32600 1.000 33.68729  ? 428 ARG B C   1 
ATOM   6835 O O   . ARG B 1 428 ? -50.36400 -20.14200 -50.72800 1.000 28.47598  ? 428 ARG B O   1 
ATOM   6836 C CB  . ARG B 1 428 ? -49.86500 -18.90500 -47.89000 1.000 32.82406  ? 428 ARG B CB  1 
ATOM   6837 C CG  . ARG B 1 428 ? -49.91100 -18.00600 -46.72700 1.000 30.06879  ? 428 ARG B CG  1 
ATOM   6838 C CD  . ARG B 1 428 ? -49.00800 -18.53700 -45.67400 1.000 30.81858  ? 428 ARG B CD  1 
ATOM   6839 N NE  . ARG B 1 428 ? -49.28900 -17.94700 -44.37300 1.000 33.48889  ? 428 ARG B NE  1 
ATOM   6840 C CZ  . ARG B 1 428 ? -48.59200 -18.21500 -43.27600 1.000 39.25726  ? 428 ARG B CZ  1 
ATOM   6841 N NH1 . ARG B 1 428 ? -47.57300 -19.06000 -43.29400 1.000 40.17018  ? 428 ARG B NH1 1 
ATOM   6842 N NH2 . ARG B 1 428 ? -48.92700 -17.62800 -42.13300 1.000 31.42597  ? 428 ARG B NH2 1 
ATOM   6843 N N   . PRO B 1 429 ? -49.69000 -18.01100 -51.02000 1.000 35.66273  ? 429 PRO B N   1 
ATOM   6844 C CA  . PRO B 1 429 ? -48.93400 -18.32600 -52.23500 1.000 35.94174  ? 429 PRO B CA  1 
ATOM   6845 C C   . PRO B 1 429 ? -47.50500 -18.73800 -51.91200 1.000 37.56994  ? 429 PRO B C   1 
ATOM   6846 O O   . PRO B 1 429 ? -46.96000 -18.42800 -50.84900 1.000 37.39397  ? 429 PRO B O   1 
ATOM   6847 C CB  . PRO B 1 429 ? -48.94000 -16.99900 -52.99400 1.000 32.82471  ? 429 PRO B CB  1 
ATOM   6848 C CG  . PRO B 1 429 ? -48.84500 -15.98800 -51.87600 1.000 34.01182  ? 429 PRO B CG  1 
ATOM   6849 C CD  . PRO B 1 429 ? -49.67800 -16.56400 -50.72700 1.000 28.97677  ? 429 PRO B CD  1 
ATOM   6850 N N   . GLU B 1 430 ? -46.88700 -19.40000 -52.88800 1.000 38.90826  ? 430 GLU B N   1 
ATOM   6851 C CA  . GLU B 1 430 ? -45.49400 -19.80000 -52.76800 1.000 41.00934  ? 430 GLU B CA  1 
ATOM   6852 C C   . GLU B 1 430 ? -44.60200 -18.58400 -52.56000 1.000 37.89697  ? 430 GLU B C   1 
ATOM   6853 O O   . GLU B 1 430 ? -44.90400 -17.47400 -53.00500 1.000 39.44247  ? 430 GLU B O   1 
ATOM   6854 C CB  . GLU B 1 430 ? -45.03500 -20.56200 -54.02000 1.000 41.35923  ? 430 GLU B CB  1 
ATOM   6855 C CG  . GLU B 1 430 ? -44.52600 -19.66700 -55.14800 1.000 43.43775  ? 430 GLU B CG  1 
ATOM   6856 C CD  . GLU B 1 430 ? -43.89300 -20.44000 -56.31800 1.000 42.25211  ? 430 GLU B CD  1 
ATOM   6857 O OE1 . GLU B 1 430 ? -42.95800 -21.23500 -56.07900 1.000 40.79385  ? 430 GLU B OE1 1 
ATOM   6858 O OE2 . GLU B 1 430 ? -44.32500 -20.24300 -57.48100 1.000 36.34387  ? 430 GLU B OE2 1 
ATOM   6859 N N   . VAL B 1 431 ? -43.50200 -18.79900 -51.85000 1.000 41.00310  ? 431 VAL B N   1 
ATOM   6860 C CA  . VAL B 1 431 ? -42.39200 -17.85500 -51.80600 1.000 46.35613  ? 431 VAL B CA  1 
ATOM   6861 C C   . VAL B 1 431 ? -41.15400 -18.63700 -52.22900 1.000 42.79510  ? 431 VAL B C   1 
ATOM   6862 O O   . VAL B 1 431 ? -40.71100 -19.54200 -51.51200 1.000 45.60931  ? 431 VAL B O   1 
ATOM   6863 C CB  . VAL B 1 431 ? -42.20500 -17.21000 -50.41400 1.000 47.85307  ? 431 VAL B CB  1 
ATOM   6864 C CG1 . VAL B 1 431 ? -43.03100 -15.93000 -50.28700 1.000 47.54015  ? 431 VAL B CG1 1 
ATOM   6865 C CG2 . VAL B 1 431 ? -42.60400 -18.16400 -49.32100 1.000 44.39213  ? 431 VAL B CG2 1 
ATOM   6866 N N   . ALA B 1 432 ? -40.61400 -18.31300 -53.40000 1.000 44.79847  ? 432 ALA B N   1 
ATOM   6867 C CA  . ALA B 1 432 ? -39.39800 -18.96500 -53.87000 1.000 45.47374  ? 432 ALA B CA  1 
ATOM   6868 C C   . ALA B 1 432 ? -38.20800 -18.57900 -52.99500 1.000 48.89939  ? 432 ALA B C   1 
ATOM   6869 O O   . ALA B 1 432 ? -37.99200 -17.39800 -52.70400 1.000 46.16285  ? 432 ALA B O   1 
ATOM   6870 C CB  . ALA B 1 432 ? -39.12100 -18.59100 -55.32600 1.000 43.69086  ? 432 ALA B CB  1 
ATOM   6871 N N   . ARG B 1 433 ? -37.43800 -19.58200 -52.57700 1.000 48.52483  ? 433 ARG B N   1 
ATOM   6872 C CA  . ARG B 1 433 ? -36.26100 -19.39200 -51.74000 1.000 48.23347  ? 433 ARG B CA  1 
ATOM   6873 C C   . ARG B 1 433 ? -35.06300 -20.04800 -52.40700 1.000 46.64181  ? 433 ARG B C   1 
ATOM   6874 O O   . ARG B 1 433 ? -35.12900 -21.21900 -52.79100 1.000 53.18312  ? 433 ARG B O   1 
ATOM   6875 C CB  . ARG B 1 433 ? -36.49000 -19.98800 -50.35100 1.000 48.75737  ? 433 ARG B CB  1 
ATOM   6876 C CG  . ARG B 1 433 ? -37.94300 -19.88300 -49.91800 1.000 61.60289  ? 433 ARG B CG  1 
ATOM   6877 C CD  . ARG B 1 433 ? -38.20400 -20.38400 -48.50000 1.000 69.13857  ? 433 ARG B CD  1 
ATOM   6878 N NE  . ARG B 1 433 ? -38.51900 -21.80700 -48.46000 1.000 74.50420  ? 433 ARG B NE  1 
ATOM   6879 C CZ  . ARG B 1 433 ? -37.71800 -22.73600 -47.95000 1.000 83.35739  ? 433 ARG B CZ  1 
ATOM   6880 N NH1 . ARG B 1 433 ? -36.55900 -22.41700 -47.38500 1.000 78.31925  ? 433 ARG B NH1 1 
ATOM   6881 N NH2 . ARG B 1 433 ? -38.09000 -24.01700 -48.00600 1.000 75.41133  ? 433 ARG B NH2 1 
ATOM   6882 N N   . THR B 1 434 ? -33.97700 -19.30000 -52.55200 1.000 48.62932  ? 434 THR B N   1 
ATOM   6883 C CA  . THR B 1 434 ? -32.69900 -19.84600 -52.99600 1.000 48.54239  ? 434 THR B CA  1 
ATOM   6884 C C   . THR B 1 434 ? -31.87100 -20.20500 -51.76800 1.000 54.85145  ? 434 THR B C   1 
ATOM   6885 O O   . THR B 1 434 ? -31.78900 -19.41700 -50.82100 1.000 54.85823  ? 434 THR B O   1 
ATOM   6886 C CB  . THR B 1 434 ? -31.93600 -18.83800 -53.86000 1.000 48.30597  ? 434 THR B CB  1 
ATOM   6887 O OG1 . THR B 1 434 ? -32.86300 -17.94200 -54.48400 1.000 51.67054  ? 434 THR B OG1 1 
ATOM   6888 C CG2 . THR B 1 434 ? -31.15900 -19.55300 -54.93900 1.000 50.91786  ? 434 THR B CG2 1 
ATOM   6889 N N   . ILE B 1 435 ? -31.27000 -21.39400 -51.77100 1.000 60.24405  ? 435 ILE B N   1 
ATOM   6890 C CA  . ILE B 1 435 ? -30.37700 -21.80900 -50.69400 1.000 54.64492  ? 435 ILE B CA  1 
ATOM   6891 C C   . ILE B 1 435 ? -29.07900 -22.30600 -51.30400 1.000 50.84459  ? 435 ILE B C   1 
ATOM   6892 O O   . ILE B 1 435 ? -29.08800 -23.00500 -52.32200 1.000 47.47462  ? 435 ILE B O   1 
ATOM   6893 C CB  . ILE B 1 435 ? -30.99900 -22.89300 -49.78900 1.000 53.35496  ? 435 ILE B CB  1 
ATOM   6894 C CG1 . ILE B 1 435 ? -31.48300 -24.08200 -50.60800 1.000 51.68415  ? 435 ILE B CG1 1 
ATOM   6895 C CG2 . ILE B 1 435 ? -32.14300 -22.31200 -48.96900 1.000 54.65291  ? 435 ILE B CG2 1 
ATOM   6896 C CD1 . ILE B 1 435 ? -32.24400 -25.10200 -49.77400 1.000 47.61400  ? 435 ILE B CD1 1 
ATOM   6897 N N   . SER B 1 436 ? -27.96300 -21.93900 -50.68400 1.000 50.10632  ? 436 SER B N   1 
ATOM   6898 C CA  . SER B 1 436 ? -26.64200 -22.34500 -51.15500 1.000 50.00756  ? 436 SER B CA  1 
ATOM   6899 C C   . SER B 1 436 ? -26.17300 -23.52600 -50.31200 1.000 47.52502  ? 436 SER B C   1 
ATOM   6900 O O   . SER B 1 436 ? -25.78000 -23.36000 -49.15500 1.000 45.21428  ? 436 SER B O   1 
ATOM   6901 C CB  . SER B 1 436 ? -25.66200 -21.18100 -51.07700 1.000 51.33454  ? 436 SER B CB  1 
ATOM   6902 O OG  . SER B 1 436 ? -26.25100 -20.00700 -51.60100 1.000 61.77091  ? 436 SER B OG  1 
ATOM   6903 N N   . TRP B 1 437 ? -26.21600 -24.72100 -50.88700 1.000 44.48569  ? 437 TRP B N   1 
ATOM   6904 C CA  . TRP B 1 437 ? -25.62500 -25.86100 -50.21400 1.000 38.80529  ? 437 TRP B CA  1 
ATOM   6905 C C   . TRP B 1 437 ? -24.10700 -25.77500 -50.29400 1.000 41.27779  ? 437 TRP B C   1 
ATOM   6906 O O   . TRP B 1 437 ? -23.54300 -25.28400 -51.27400 1.000 44.51571  ? 437 TRP B O   1 
ATOM   6907 C CB  . TRP B 1 437 ? -26.11600 -27.15700 -50.83100 1.000 34.91767  ? 437 TRP B CB  1 
ATOM   6908 C CG  . TRP B 1 437 ? -27.57500 -27.33700 -50.69300 1.000 41.51665  ? 437 TRP B CG  1 
ATOM   6909 C CD1 . TRP B 1 437 ? -28.53600 -26.89400 -51.55100 1.000 42.89382  ? 437 TRP B CD1 1 
ATOM   6910 C CD2 . TRP B 1 437 ? -28.25600 -28.03100 -49.64400 1.000 40.72673  ? 437 TRP B CD2 1 
ATOM   6911 N NE1 . TRP B 1 437 ? -29.77700 -27.26400 -51.10100 1.000 48.59963  ? 437 TRP B NE1 1 
ATOM   6912 C CE2 . TRP B 1 437 ? -29.63800 -27.96100 -49.92900 1.000 42.72620  ? 437 TRP B CE2 1 
ATOM   6913 C CE3 . TRP B 1 437 ? -27.83400 -28.70100 -48.48500 1.000 37.13088  ? 437 TRP B CE3 1 
ATOM   6914 C CZ2 . TRP B 1 437 ? -30.61000 -28.53600 -49.09700 1.000 40.87898  ? 437 TRP B CZ2 1 
ATOM   6915 C CZ3 . TRP B 1 437 ? -28.79800 -29.27400 -47.65800 1.000 35.27981  ? 437 TRP B CZ3 1 
ATOM   6916 C CH2 . TRP B 1 437 ? -30.17300 -29.18800 -47.97300 1.000 42.88356  ? 437 TRP B CH2 1 
ATOM   6917 N N   . ALA B 1 438 ? -23.44200 -26.23500 -49.23300 1.000 39.73649  ? 438 ALA B N   1 
ATOM   6918 C CA  . ALA B 1 438 ? -21.97800 -26.28600 -49.20400 1.000 39.94816  ? 438 ALA B CA  1 
ATOM   6919 C C   . ALA B 1 438 ? -21.53800 -27.58900 -49.85400 1.000 38.51351  ? 438 ALA B C   1 
ATOM   6920 O O   . ALA B 1 438 ? -21.24400 -28.59400 -49.19400 1.000 37.32058  ? 438 ALA B O   1 
ATOM   6921 C CB  . ALA B 1 438 ? -21.46000 -26.16800 -47.77900 1.000 42.67361  ? 438 ALA B CB  1 
ATOM   6922 N N   . GLY B 1 439 ? -21.49300 -27.56200 -51.17400 1.000 38.98977  ? 439 GLY B N   1 
ATOM   6923 C CA  . GLY B 1 439 ? -21.30600 -28.75300 -51.97200 1.000 38.87877  ? 439 GLY B CA  1 
ATOM   6924 C C   . GLY B 1 439 ? -22.61200 -29.22700 -52.60200 1.000 40.80610  ? 439 GLY B C   1 
ATOM   6925 O O   . GLY B 1 439 ? -23.71800 -28.89200 -52.16300 1.000 39.20856  ? 439 GLY B O   1 
ATOM   6926 N N   . ASN B 1 440 ? -22.46800 -30.01300 -53.65400 1.000 40.57761  ? 440 ASN B N   1 
ATOM   6927 C CA  . ASN B 1 440 ? -23.61400 -30.58900 -54.34000 1.000 50.15606  ? 440 ASN B CA  1 
ATOM   6928 C C   . ASN B 1 440 ? -24.32600 -31.56900 -53.41600 1.000 49.42130  ? 440 ASN B C   1 
ATOM   6929 O O   . ASN B 1 440 ? -23.76300 -32.63100 -53.11300 1.000 46.81952  ? 440 ASN B O   1 
ATOM   6930 C CB  . ASN B 1 440 ? -23.14300 -31.27600 -55.62100 1.000 52.21624  ? 440 ASN B CB  1 
ATOM   6931 C CG  . ASN B 1 440 ? -24.19100 -32.18100 -56.22900 1.000 51.62906  ? 440 ASN B CG  1 
ATOM   6932 O OD1 . ASN B 1 440 ? -25.39100 -32.05900 -55.96200 1.000 52.39872  ? 440 ASN B OD1 1 
ATOM   6933 N ND2 . ASN B 1 440 ? -23.73600 -33.10600 -57.06300 1.000 59.05530  ? 440 ASN B ND2 1 
ATOM   6934 N N   . PRO B 1 441 ? -25.55600 -31.27800 -52.97300 1.000 48.92542  ? 441 PRO B N   1 
ATOM   6935 C CA  . PRO B 1 441 ? -26.21100 -32.11700 -51.95600 1.000 45.34064  ? 441 PRO B CA  1 
ATOM   6936 C C   . PRO B 1 441 ? -26.79100 -33.41200 -52.49100 1.000 47.74193  ? 441 PRO B C   1 
ATOM   6937 O O   . PRO B 1 441 ? -27.11500 -34.30500 -51.69500 1.000 46.97927  ? 441 PRO B O   1 
ATOM   6938 C CB  . PRO B 1 441 ? -27.32000 -31.20400 -51.41600 1.000 43.26176  ? 441 PRO B CB  1 
ATOM   6939 C CG  . PRO B 1 441 ? -27.63800 -30.29000 -52.55200 1.000 46.89500  ? 441 PRO B CG  1 
ATOM   6940 C CD  . PRO B 1 441 ? -26.40300 -30.15600 -53.40900 1.000 46.84014  ? 441 PRO B CD  1 
ATOM   6941 N N   . ARG B 1 442 ? -26.93500 -33.55100 -53.80600 1.000 50.67239  ? 442 ARG B N   1 
ATOM   6942 C CA  . ARG B 1 442 ? -27.39100 -34.82600 -54.34000 1.000 55.44808  ? 442 ARG B CA  1 
ATOM   6943 C C   . ARG B 1 442 ? -26.31700 -35.89300 -54.19500 1.000 51.67201  ? 442 ARG B C   1 
ATOM   6944 O O   . ARG B 1 442 ? -26.63600 -37.08300 -54.08800 1.000 46.02987  ? 442 ARG B O   1 
ATOM   6945 C CB  . ARG B 1 442 ? -27.81900 -34.65700 -55.79800 1.000 64.07825  ? 442 ARG B CB  1 
ATOM   6946 C CG  . ARG B 1 442 ? -29.01000 -33.69200 -55.97800 1.000 72.95576  ? 442 ARG B CG  1 
ATOM   6947 C CD  . ARG B 1 442 ? -29.57100 -33.69200 -57.40900 1.000 82.57979  ? 442 ARG B CD  1 
ATOM   6948 N NE  . ARG B 1 442 ? -28.56000 -33.34500 -58.40400 1.000 91.10996  ? 442 ARG B NE  1 
ATOM   6949 C CZ  . ARG B 1 442 ? -27.86200 -34.23000 -59.10800 1.000 95.79951  ? 442 ARG B CZ  1 
ATOM   6950 N NH1 . ARG B 1 442 ? -28.06400 -35.53400 -58.97700 1.000 91.09378  ? 442 ARG B NH1 1 
ATOM   6951 N NH2 . ARG B 1 442 ? -26.93400 -33.79700 -59.96100 1.000 92.07731  ? 442 ARG B NH2 1 
ATOM   6952 N N   . LYS B 1 443 ? -25.04600 -35.47800 -54.14500 1.000 48.64273  ? 443 LYS B N   1 
ATOM   6953 C CA  . LYS B 1 443 ? -23.90200 -36.35600 -53.91000 1.000 48.24314  ? 443 LYS B CA  1 
ATOM   6954 C C   . LYS B 1 443 ? -23.17700 -35.89900 -52.64700 1.000 45.97573  ? 443 LYS B C   1 
ATOM   6955 O O   . LYS B 1 443 ? -22.12500 -35.24500 -52.71700 1.000 43.48945  ? 443 LYS B O   1 
ATOM   6956 C CB  . LYS B 1 443 ? -22.97100 -36.36800 -55.12000 1.000 55.73761  ? 443 LYS B CB  1 
ATOM   6957 C CG  . LYS B 1 443 ? -23.53800 -37.14700 -56.31600 1.000 61.19731  ? 443 LYS B CG  1 
ATOM   6958 C CD  . LYS B 1 443 ? -22.43600 -37.55300 -57.30200 1.000 72.66498  ? 443 LYS B CD  1 
ATOM   6959 C CE  . LYS B 1 443 ? -21.12600 -37.95400 -56.58400 1.000 72.17501  ? 443 LYS B CE  1 
ATOM   6960 N NZ  . LYS B 1 443 ? -21.27000 -39.03600 -55.54800 1.000 63.14977  ? 443 LYS B NZ  1 
ATOM   6961 N N   . PRO B 1 444 ? -23.71700 -36.22000 -51.46600 1.000 47.47376  ? 444 PRO B N   1 
ATOM   6962 C CA  . PRO B 1 444 ? -23.08600 -35.75500 -50.21900 1.000 48.68642  ? 444 PRO B CA  1 
ATOM   6963 C C   . PRO B 1 444 ? -21.87600 -36.56700 -49.78300 1.000 44.57840  ? 444 PRO B C   1 
ATOM   6964 O O   . PRO B 1 444 ? -21.11700 -36.09900 -48.92800 1.000 42.80942  ? 444 PRO B O   1 
ATOM   6965 C CB  . PRO B 1 444 ? -24.22100 -35.87800 -49.19700 1.000 41.59586  ? 444 PRO B CB  1 
ATOM   6966 C CG  . PRO B 1 444 ? -25.02700 -37.01100 -49.71300 1.000 43.15555  ? 444 PRO B CG  1 
ATOM   6967 C CD  . PRO B 1 444 ? -24.99600 -36.90400 -51.20900 1.000 44.23705  ? 444 PRO B CD  1 
ATOM   6968 N N   . ALA B 1 445 ? -21.68600 -37.76700 -50.31900 1.000 46.49698  ? 445 ALA B N   1 
ATOM   6969 C CA  . ALA B 1 445 ? -20.55400 -38.61400 -49.99300 1.000 44.57774  ? 445 ALA B CA  1 
ATOM   6970 C C   . ALA B 1 445 ? -20.00100 -39.18500 -51.29000 1.000 50.48858  ? 445 ALA B C   1 
ATOM   6971 O O   . ALA B 1 445 ? -20.54500 -38.95200 -52.37400 1.000 50.78585  ? 445 ALA B O   1 
ATOM   6972 C CB  . ALA B 1 445 ? -20.95700 -39.72600 -49.02100 1.000 45.84996  ? 445 ALA B CB  1 
ATOM   6973 N N   . GLU B 1 446 ? -18.90500 -39.92900 -51.17800 1.000 48.90597  ? 446 GLU B N   1 
ATOM   6974 C CA  . GLU B 1 446 ? -18.28500 -40.60400 -52.31800 1.000 50.93815  ? 446 GLU B CA  1 
ATOM   6975 C C   . GLU B 1 446 ? -18.05300 -42.05800 -51.93100 1.000 50.48062  ? 446 GLU B C   1 
ATOM   6976 O O   . GLU B 1 446 ? -17.12600 -42.35100 -51.15800 1.000 47.20761  ? 446 GLU B O   1 
ATOM   6977 C CB  . GLU B 1 446 ? -16.96700 -39.94400 -52.72400 1.000 49.58993  ? 446 GLU B CB  1 
ATOM   6978 C CG  . GLU B 1 446 ? -17.06000 -38.48500 -53.22400 1.000 57.83856  ? 446 GLU B CG  1 
ATOM   6979 C CD  . GLU B 1 446 ? -17.73500 -38.33700 -54.59100 1.000 72.64392  ? 446 GLU B CD  1 
ATOM   6980 O OE1 . GLU B 1 446 ? -18.05600 -39.36900 -55.23300 1.000 73.57781  ? 446 GLU B OE1 1 
ATOM   6981 O OE2 . GLU B 1 446 ? -17.94800 -37.17700 -55.02000 1.000 73.13777  ? 446 GLU B OE2 1 
ATOM   6982 N N   . PRO B 1 447 ? -18.87000 -42.99300 -52.41800 1.000 53.82053  ? 447 PRO B N   1 
ATOM   6983 C CA  . PRO B 1 447 ? -18.60500 -44.40700 -52.13100 1.000 55.09906  ? 447 PRO B CA  1 
ATOM   6984 C C   . PRO B 1 447 ? -17.63900 -45.00900 -53.13800 1.000 50.02749  ? 447 PRO B C   1 
ATOM   6985 O O   . PRO B 1 447 ? -17.65500 -44.68000 -54.32600 1.000 52.12596  ? 447 PRO B O   1 
ATOM   6986 C CB  . PRO B 1 447 ? -19.99500 -45.04700 -52.25300 1.000 55.70256  ? 447 PRO B CB  1 
ATOM   6987 C CG  . PRO B 1 447 ? -20.66800 -44.22400 -53.28900 1.000 50.87604  ? 447 PRO B CG  1 
ATOM   6988 C CD  . PRO B 1 447 ? -20.15800 -42.80800 -53.11100 1.000 51.93652  ? 447 PRO B CD  1 
ATOM   6989 N N   . GLU B 1 448 ? -16.76900 -45.88600 -52.64100 1.000 46.59257  ? 448 GLU B N   1 
ATOM   6990 C CA  . GLU B 1 448 ? -15.96000 -46.70800 -53.51700 1.000 42.04090  ? 448 GLU B CA  1 
ATOM   6991 C C   . GLU B 1 448 ? -16.84400 -47.77200 -54.14800 1.000 42.19562  ? 448 GLU B C   1 
ATOM   6992 O O   . GLU B 1 448 ? -17.97000 -47.99700 -53.69400 1.000 52.37237  ? 448 GLU B O   1 
ATOM   6993 C CB  . GLU B 1 448 ? -14.81900 -47.35400 -52.73900 1.000 45.40141  ? 448 GLU B CB  1 
ATOM   6994 C CG  . GLU B 1 448 ? -13.83200 -46.35300 -52.14400 1.000 45.14272  ? 448 GLU B CG  1 
ATOM   6995 C CD  . GLU B 1 448 ? -12.56300 -47.01300 -51.64400 1.000 47.51441  ? 448 GLU B CD  1 
ATOM   6996 O OE1 . GLU B 1 448 ? -12.45500 -48.25500 -51.71600 1.000 51.97890  ? 448 GLU B OE1 1 
ATOM   6997 O OE2 . GLU B 1 448 ? -11.66700 -46.29300 -51.17200 1.000 46.76217  ? 448 GLU B OE2 1 
ATOM   6998 N N   . PRO B 1 449 ? -16.38700 -48.40700 -55.22700 1.000 44.41386  ? 449 PRO B N   1 
ATOM   6999 C CA  . PRO B 1 449 ? -17.15100 -49.53100 -55.78200 1.000 43.78033  ? 449 PRO B CA  1 
ATOM   7000 C C   . PRO B 1 449 ? -17.34900 -50.61600 -54.73600 1.000 44.47607  ? 449 PRO B C   1 
ATOM   7001 O O   . PRO B 1 449 ? -16.45600 -50.89900 -53.93200 1.000 47.79793  ? 449 PRO B O   1 
ATOM   7002 C CB  . PRO B 1 449 ? -16.27500 -50.01400 -56.94000 1.000 43.79141  ? 449 PRO B CB  1 
ATOM   7003 C CG  . PRO B 1 449 ? -15.55400 -48.78100 -57.37900 1.000 41.05318  ? 449 PRO B CG  1 
ATOM   7004 C CD  . PRO B 1 449 ? -15.28100 -48.00700 -56.11800 1.000 42.92157  ? 449 PRO B CD  1 
ATOM   7005 N N   . GLY B 1 450 ? -18.53800 -51.21900 -54.74300 1.000 42.89967  ? 450 GLY B N   1 
ATOM   7006 C CA  . GLY B 1 450 ? -18.90600 -52.21400 -53.76200 1.000 49.60902  ? 450 GLY B CA  1 
ATOM   7007 C C   . GLY B 1 450 ? -19.64400 -51.63900 -52.57300 1.000 54.23367  ? 450 GLY B C   1 
ATOM   7008 O O   . GLY B 1 450 ? -20.40900 -52.35500 -51.91700 1.000 60.64877  ? 450 GLY B O   1 
ATOM   7009 N N   . HIS B 1 451 ? -19.41400 -50.35900 -52.28200 1.000 54.92303  ? 451 HIS B N   1 
ATOM   7010 C CA  . HIS B 1 451 ? -20.23600 -49.53100 -51.40700 1.000 57.78985  ? 451 HIS B CA  1 
ATOM   7011 C C   . HIS B 1 451 ? -20.04700 -49.84900 -49.93700 1.000 57.16478  ? 451 HIS B C   1 
ATOM   7012 O O   . HIS B 1 451 ? -20.88400 -49.47400 -49.10700 1.000 70.91351  ? 451 HIS B O   1 
ATOM   7013 C CB  . HIS B 1 451 ? -21.71800 -49.61200 -51.79600 1.000 55.32274  ? 451 HIS B CB  1 
ATOM   7014 C CG  . HIS B 1 451 ? -22.02200 -48.91200 -53.08200 1.000 60.92066  ? 451 HIS B CG  1 
ATOM   7015 N ND1 . HIS B 1 451 ? -21.85300 -49.51000 -54.31200 1.000 63.05139  ? 451 HIS B ND1 1 
ATOM   7016 C CD2 . HIS B 1 451 ? -22.43400 -47.64600 -53.33300 1.000 66.51425  ? 451 HIS B CD2 1 
ATOM   7017 C CE1 . HIS B 1 451 ? -22.16800 -48.65100 -55.26500 1.000 66.35649  ? 451 HIS B CE1 1 
ATOM   7018 N NE2 . HIS B 1 451 ? -22.52700 -47.51300 -54.69800 1.000 70.57609  ? 451 HIS B NE2 1 
ATOM   7019 N N   . GLN B 1 452 ? -18.95000 -50.50700 -49.58900 1.000 56.36891  ? 452 GLN B N   1 
ATOM   7020 C CA  . GLN B 1 452 ? -18.58600 -50.70500 -48.19700 1.000 61.66263  ? 452 GLN B CA  1 
ATOM   7021 C C   . GLN B 1 452 ? -17.59600 -49.66100 -47.69000 1.000 58.72401  ? 452 GLN B C   1 
ATOM   7022 O O   . GLN B 1 452 ? -17.22700 -49.70100 -46.51200 1.000 60.48987  ? 452 GLN B O   1 
ATOM   7023 C CB  . GLN B 1 452 ? -18.01200 -52.10600 -48.00800 1.000 63.20909  ? 452 GLN B CB  1 
ATOM   7024 C CG  . GLN B 1 452 ? -18.65900 -53.15700 -48.89800 1.000 64.28665  ? 452 GLN B CG  1 
ATOM   7025 C CD  . GLN B 1 452 ? -18.06500 -54.53500 -48.66700 1.000 72.57692  ? 452 GLN B CD  1 
ATOM   7026 O OE1 . GLN B 1 452 ? -17.17700 -54.70300 -47.82900 1.000 71.74791  ? 452 GLN B OE1 1 
ATOM   7027 N NE2 . GLN B 1 452 ? -18.55500 -55.52900 -49.40300 1.000 68.97110  ? 452 GLN B NE2 1 
ATOM   7028 N N   . ARG B 1 453 ? -17.16100 -48.73100 -48.54500 1.000 59.24858  ? 453 ARG B N   1 
ATOM   7029 C CA  . ARG B 1 453 ? -16.22100 -47.67000 -48.17800 1.000 51.48616  ? 453 ARG B CA  1 
ATOM   7030 C C   . ARG B 1 453 ? -16.79200 -46.33600 -48.62300 1.000 49.10895  ? 453 ARG B C   1 
ATOM   7031 O O   . ARG B 1 453 ? -16.86400 -46.05800 -49.82400 1.000 50.87176  ? 453 ARG B O   1 
ATOM   7032 C CB  . ARG B 1 453 ? -14.84800 -47.87800 -48.81300 1.000 49.08449  ? 453 ARG B CB  1 
ATOM   7033 C CG  . ARG B 1 453 ? -13.77600 -48.36300 -47.86300 1.000 56.19470  ? 453 ARG B CG  1 
ATOM   7034 C CD  . ARG B 1 453 ? -12.52400 -48.74200 -48.64400 1.000 59.28358  ? 453 ARG B CD  1 
ATOM   7035 N NE  . ARG B 1 453 ? -11.78700 -49.82700 -48.01300 1.000 58.00661  ? 453 ARG B NE  1 
ATOM   7036 C CZ  . ARG B 1 453 ? -10.60500 -49.69600 -47.43000 1.000 58.61609  ? 453 ARG B CZ  1 
ATOM   7037 N NH1 . ARG B 1 453 ? -9.98900  -48.52400 -47.37300 1.000 54.68520  ? 453 ARG B NH1 1 
ATOM   7038 N NH2 . ARG B 1 453 ? -10.01900 -50.77300 -46.90700 1.000 55.20731  ? 453 ARG B NH2 1 
ATOM   7039 N N   . LEU B 1 454 ? -17.17700 -45.50900 -47.66100 1.000 53.39697  ? 454 LEU B N   1 
ATOM   7040 C CA  . LEU B 1 454 ? -17.67900 -44.17400 -47.94100 1.000 51.70719  ? 454 LEU B CA  1 
ATOM   7041 C C   . LEU B 1 454 ? -16.58100 -43.14800 -47.69300 1.000 53.68593  ? 454 LEU B C   1 
ATOM   7042 O O   . LEU B 1 454 ? -15.66700 -43.36000 -46.89100 1.000 51.27519  ? 454 LEU B O   1 
ATOM   7043 C CB  . LEU B 1 454 ? -18.90900 -43.85200 -47.08800 1.000 50.01591  ? 454 LEU B CB  1 
ATOM   7044 C CG  . LEU B 1 454 ? -20.26800 -44.29600 -47.63700 1.000 55.70690  ? 454 LEU B CG  1 
ATOM   7045 C CD1 . LEU B 1 454 ? -20.32900 -45.80500 -47.89500 1.000 56.90490  ? 454 LEU B CD1 1 
ATOM   7046 C CD2 . LEU B 1 454 ? -21.38300 -43.86800 -46.69500 1.000 56.22388  ? 454 LEU B CD2 1 
ATOM   7047 N N   . HIS B 1 455 ? -16.66300 -42.04400 -48.41700 1.000 53.37291  ? 455 HIS B N   1 
ATOM   7048 C CA  . HIS B 1 455 ? -15.76200 -40.92700 -48.22400 1.000 45.59248  ? 455 HIS B CA  1 
ATOM   7049 C C   . HIS B 1 455 ? -16.59200 -39.65500 -48.21000 1.000 48.61089  ? 455 HIS B C   1 
ATOM   7050 O O   . HIS B 1 455 ? -17.68100 -39.60900 -48.79400 1.000 50.39787  ? 455 HIS B O   1 
ATOM   7051 C CB  . HIS B 1 455 ? -14.69400 -40.85300 -49.32800 1.000 39.92999  ? 455 HIS B CB  1 
ATOM   7052 C CG  . HIS B 1 455 ? -13.73100 -42.00000 -49.32000 1.000 48.83634  ? 455 HIS B CG  1 
ATOM   7053 N ND1 . HIS B 1 455 ? -12.44700 -41.89300 -48.82900 1.000 46.15537  ? 455 HIS B ND1 1 
ATOM   7054 C CD2 . HIS B 1 455 ? -13.86000 -43.27600 -49.75700 1.000 50.61819  ? 455 HIS B CD2 1 
ATOM   7055 C CE1 . HIS B 1 455 ? -11.83000 -43.05400 -48.95700 1.000 49.59255  ? 455 HIS B CE1 1 
ATOM   7056 N NE2 . HIS B 1 455 ? -12.66500 -43.91200 -49.51600 1.000 47.78664  ? 455 HIS B NE2 1 
ATOM   7057 N N   . PRO B 1 456 ? -16.13400 -38.62600 -47.51100 1.000 51.35025  ? 456 PRO B N   1 
ATOM   7058 C CA  . PRO B 1 456 ? -16.81300 -37.33200 -47.59200 1.000 47.28388  ? 456 PRO B CA  1 
ATOM   7059 C C   . PRO B 1 456 ? -16.66800 -36.77200 -48.99700 1.000 47.03389  ? 456 PRO B C   1 
ATOM   7060 O O   . PRO B 1 456 ? -15.82000 -37.20600 -49.78300 1.000 42.25518  ? 456 PRO B O   1 
ATOM   7061 C CB  . PRO B 1 456 ? -16.07000 -36.48600 -46.55600 1.000 47.93388  ? 456 PRO B CB  1 
ATOM   7062 C CG  . PRO B 1 456 ? -14.68000 -37.11200 -46.50400 1.000 41.66429  ? 456 PRO B CG  1 
ATOM   7063 C CD  . PRO B 1 456 ? -14.92100 -38.57600 -46.66900 1.000 44.98255  ? 456 PRO B CD  1 
ATOM   7064 N N   . ARG B 1 457 ? -17.52500 -35.81000 -49.32100 1.000 45.31758  ? 457 ARG B N   1 
ATOM   7065 C CA  . ARG B 1 457 ? -17.40500 -35.13700 -50.60600 1.000 43.61705  ? 457 ARG B CA  1 
ATOM   7066 C C   . ARG B 1 457 ? -16.08200 -34.37000 -50.68000 1.000 45.75221  ? 457 ARG B C   1 
ATOM   7067 O O   . ARG B 1 457 ? -15.46800 -34.03600 -49.66100 1.000 48.10636  ? 457 ARG B O   1 
ATOM   7068 C CB  . ARG B 1 457 ? -18.58900 -34.19600 -50.81700 1.000 36.52328  ? 457 ARG B CB  1 
ATOM   7069 C CG  . ARG B 1 457 ? -18.77800 -33.18400 -49.71600 1.000 40.74186  ? 457 ARG B CG  1 
ATOM   7070 C CD  . ARG B 1 457 ? -20.15700 -32.53900 -49.84600 1.000 40.14309  ? 457 ARG B CD  1 
ATOM   7071 N NE  . ARG B 1 457 ? -20.40500 -31.47100 -48.88200 1.000 37.58640  ? 457 ARG B NE  1 
ATOM   7072 C CZ  . ARG B 1 457 ? -21.03700 -31.63300 -47.72600 1.000 36.92460  ? 457 ARG B CZ  1 
ATOM   7073 N NH1 . ARG B 1 457 ? -21.42700 -32.83200 -47.30900 1.000 32.61813  ? 457 ARG B NH1 1 
ATOM   7074 N NH2 . ARG B 1 457 ? -21.29000 -30.56600 -46.97200 1.000 33.03427  ? 457 ARG B NH2 1 
ATOM   7075 N N   . GLY B 1 458 ? -15.63200 -34.09300 -51.90300 1.000 43.76121  ? 458 GLY B N   1 
ATOM   7076 C CA  . GLY B 1 458 ? -14.34000 -33.44200 -52.05200 1.000 39.76142  ? 458 GLY B CA  1 
ATOM   7077 C C   . GLY B 1 458 ? -14.43600 -31.93500 -52.12700 1.000 42.47068  ? 458 GLY B C   1 
ATOM   7078 O O   . GLY B 1 458 ? -13.45500 -31.22000 -51.91400 1.000 47.73464  ? 458 GLY B O   1 
ATOM   7079 N N   . SER B 1 459 ? -15.63200 -31.44100 -52.42800 1.000 47.70802  ? 459 SER B N   1 
ATOM   7080 C CA  . SER B 1 459 ? -15.87000 -30.03300 -52.68500 1.000 42.29290  ? 459 SER B CA  1 
ATOM   7081 C C   . SER B 1 459 ? -16.88000 -29.46700 -51.69600 1.000 45.92531  ? 459 SER B C   1 
ATOM   7082 O O   . SER B 1 459 ? -17.76200 -30.17200 -51.19300 1.000 47.61346  ? 459 SER B O   1 
ATOM   7083 C CB  . SER B 1 459 ? -16.38800 -29.81700 -54.10900 1.000 44.78051  ? 459 SER B CB  1 
ATOM   7084 O OG  . SER B 1 459 ? -16.28200 -28.45400 -54.48900 1.000 54.73782  ? 459 SER B OG  1 
ATOM   7085 N N   . PHE B 1 460 ? -16.75500 -28.16900 -51.44100 1.000 44.36489  ? 460 PHE B N   1 
ATOM   7086 C CA  . PHE B 1 460 ? -17.67600 -27.45500 -50.57300 1.000 45.78376  ? 460 PHE B CA  1 
ATOM   7087 C C   . PHE B 1 460 ? -18.17300 -26.17000 -51.21500 1.000 49.49419  ? 460 PHE B C   1 
ATOM   7088 O O   . PHE B 1 460 ? -18.87500 -25.39400 -50.55500 1.000 49.33852  ? 460 PHE B O   1 
ATOM   7089 C CB  . PHE B 1 460 ? -17.00500 -27.14800 -49.22300 1.000 45.16642  ? 460 PHE B CB  1 
ATOM   7090 C CG  . PHE B 1 460 ? -16.70800 -28.37200 -48.40600 1.000 39.56990  ? 460 PHE B CG  1 
ATOM   7091 C CD1 . PHE B 1 460 ? -15.49800 -29.05100 -48.55300 1.000 49.51375  ? 460 PHE B CD1 1 
ATOM   7092 C CD2 . PHE B 1 460 ? -17.63000 -28.84800 -47.49500 1.000 43.35703  ? 460 PHE B CD2 1 
ATOM   7093 C CE1 . PHE B 1 460 ? -15.21200 -30.18800 -47.80100 1.000 40.39900  ? 460 PHE B CE1 1 
ATOM   7094 C CE2 . PHE B 1 460 ? -17.36100 -29.99700 -46.73800 1.000 45.35362  ? 460 PHE B CE2 1 
ATOM   7095 C CZ  . PHE B 1 460 ? -16.14900 -30.66300 -46.89300 1.000 39.62336  ? 460 PHE B CZ  1 
ATOM   7096 N N   . GLN B 1 461 ? -17.82000 -25.92100 -52.47500 1.000 51.31908  ? 461 GLN B N   1 
ATOM   7097 C CA  . GLN B 1 461 ? -18.15100 -24.64900 -53.09700 1.000 52.64338  ? 461 GLN B CA  1 
ATOM   7098 C C   . GLN B 1 461 ? -19.66400 -24.54300 -53.28500 1.000 50.50586  ? 461 GLN B C   1 
ATOM   7099 O O   . GLN B 1 461 ? -20.37300 -25.55300 -53.37100 1.000 44.61414  ? 461 GLN B O   1 
ATOM   7100 C CB  . GLN B 1 461 ? -17.39900 -24.49700 -54.42600 1.000 47.19337  ? 461 GLN B CB  1 
ATOM   7101 C CG  . GLN B 1 461 ? -16.79000 -23.08300 -54.67200 1.000 68.02146  ? 461 GLN B CG  1 
ATOM   7102 C CD  . GLN B 1 461 ? -15.45300 -22.80000 -53.94200 1.000 74.54872  ? 461 GLN B CD  1 
ATOM   7103 O OE1 . GLN B 1 461 ? -15.12100 -23.42300 -52.92200 1.000 72.92595  ? 461 GLN B OE1 1 
ATOM   7104 N NE2 . GLN B 1 461 ? -14.68300 -21.84800 -54.48300 1.000 61.81453  ? 461 GLN B NE2 1 
ATOM   7105 N N   . ALA B 1 462 ? -20.16000 -23.30300 -53.31200 1.000 45.57922  ? 462 ALA B N   1 
ATOM   7106 C CA  . ALA B 1 462 ? -21.60200 -23.07200 -53.29200 1.000 44.65907  ? 462 ALA B CA  1 
ATOM   7107 C C   . ALA B 1 462 ? -22.28900 -23.79600 -54.44600 1.000 46.03216  ? 462 ALA B C   1 
ATOM   7108 O O   . ALA B 1 462 ? -21.94600 -23.60400 -55.61700 1.000 50.30799  ? 462 ALA B O   1 
ATOM   7109 C CB  . ALA B 1 462 ? -21.89900 -21.57300 -53.33600 1.000 38.09921  ? 462 ALA B CB  1 
ATOM   7110 N N   . TRP B 1 463 ? -23.23700 -24.66000 -54.10300 1.000 42.41866  ? 463 TRP B N   1 
ATOM   7111 C CA  . TRP B 1 463 ? -24.08700 -25.34200 -55.06700 1.000 44.76039  ? 463 TRP B CA  1 
ATOM   7112 C C   . TRP B 1 463 ? -25.51200 -24.91000 -54.77300 1.000 47.73803  ? 463 TRP B C   1 
ATOM   7113 O O   . TRP B 1 463 ? -26.04500 -25.21800 -53.70400 1.000 46.07654  ? 463 TRP B O   1 
ATOM   7114 C CB  . TRP B 1 463 ? -23.93600 -26.85200 -54.94900 1.000 45.55320  ? 463 TRP B CB  1 
ATOM   7115 C CG  . TRP B 1 463 ? -24.52300 -27.62400 -56.06900 1.000 53.16150  ? 463 TRP B CG  1 
ATOM   7116 C CD1 . TRP B 1 463 ? -23.85400 -28.17500 -57.12500 1.000 54.56205  ? 463 TRP B CD1 1 
ATOM   7117 C CD2 . TRP B 1 463 ? -25.90300 -27.96800 -56.24400 1.000 56.29665  ? 463 TRP B CD2 1 
ATOM   7118 N NE1 . TRP B 1 463 ? -24.73300 -28.83300 -57.95100 1.000 54.09497  ? 463 TRP B NE1 1 
ATOM   7119 C CE2 . TRP B 1 463 ? -25.99700 -28.72400 -57.43200 1.000 59.18582  ? 463 TRP B CE2 1 
ATOM   7120 C CE3 . TRP B 1 463 ? -27.07000 -27.71000 -55.51400 1.000 55.86115  ? 463 TRP B CE3 1 
ATOM   7121 C CZ2 . TRP B 1 463 ? -27.21600 -29.22700 -57.90800 1.000 65.36522  ? 463 TRP B CZ2 1 
ATOM   7122 C CZ3 . TRP B 1 463 ? -28.28600 -28.21800 -55.98700 1.000 61.61735  ? 463 TRP B CZ3 1 
ATOM   7123 C CH2 . TRP B 1 463 ? -28.34600 -28.96100 -57.17500 1.000 62.29598  ? 463 TRP B CH2 1 
ATOM   7124 N N   . GLU B 1 464 ? -26.12800 -24.20500 -55.71400 1.000 56.61490  ? 464 GLU B N   1 
ATOM   7125 C CA  . GLU B 1 464 ? -27.30900 -23.39900 -55.44200 1.000 52.52251  ? 464 GLU B CA  1 
ATOM   7126 C C   . GLU B 1 464 ? -28.58900 -24.07600 -55.92500 1.000 54.00819  ? 464 GLU B C   1 
ATOM   7127 O O   . GLU B 1 464 ? -28.59000 -24.81500 -56.91400 1.000 55.73968  ? 464 GLU B O   1 
ATOM   7128 C CB  . GLU B 1 464 ? -27.14100 -22.03300 -56.09300 1.000 50.20695  ? 464 GLU B CB  1 
ATOM   7129 C CG  . GLU B 1 464 ? -28.39800 -21.28500 -56.32900 1.000 55.62372  ? 464 GLU B CG  1 
ATOM   7130 C CD  . GLU B 1 464 ? -28.13500 -19.80600 -56.44400 1.000 65.45449  ? 464 GLU B CD  1 
ATOM   7131 O OE1 . GLU B 1 464 ? -27.27600 -19.30600 -55.67100 1.000 57.37875  ? 464 GLU B OE1 1 
ATOM   7132 O OE2 . GLU B 1 464 ? -28.77300 -19.16100 -57.31500 1.000 65.41139  ? 464 GLU B OE2 1 
ATOM   7133 N N   . GLU B 1 465 ? -29.68200 -23.82100 -55.20400 1.000 51.02642  ? 465 GLU B N   1 
ATOM   7134 C CA  . GLU B 1 465 ? -30.94700 -24.49900 -55.44700 1.000 47.47513  ? 465 GLU B CA  1 
ATOM   7135 C C   . GLU B 1 465 ? -32.09700 -23.59900 -55.02200 1.000 52.44995  ? 465 GLU B C   1 
ATOM   7136 O O   . GLU B 1 465 ? -32.09400 -23.06800 -53.90700 1.000 52.18312  ? 465 GLU B O   1 
ATOM   7137 C CB  . GLU B 1 465 ? -31.01100 -25.82300 -54.68000 1.000 51.34022  ? 465 GLU B CB  1 
ATOM   7138 C CG  . GLU B 1 465 ? -32.41700 -26.39600 -54.55300 1.000 50.04272  ? 465 GLU B CG  1 
ATOM   7139 C CD  . GLU B 1 465 ? -32.61700 -27.15700 -53.25600 1.000 56.52383  ? 465 GLU B CD  1 
ATOM   7140 O OE1 . GLU B 1 465 ? -31.65000 -27.78100 -52.75500 1.000 61.12546  ? 465 GLU B OE1 1 
ATOM   7141 O OE2 . GLU B 1 465 ? -33.74600 -27.11900 -52.72200 1.000 59.31533  ? 465 GLU B OE2 1 
ATOM   7142 N N   . THR B 1 466 ? -33.07800 -23.44000 -55.90700 1.000 54.46921  ? 466 THR B N   1 
ATOM   7143 C CA  . THR B 1 466 ? -34.26800 -22.65400 -55.61900 1.000 50.69640  ? 466 THR B CA  1 
ATOM   7144 C C   . THR B 1 466 ? -35.42100 -23.59400 -55.30700 1.000 43.41667  ? 466 THR B C   1 
ATOM   7145 O O   . THR B 1 466 ? -35.63100 -24.58300 -56.01300 1.000 49.32851  ? 466 THR B O   1 
ATOM   7146 C CB  . THR B 1 466 ? -34.63500 -21.73100 -56.78600 1.000 51.09060  ? 466 THR B CB  1 
ATOM   7147 O OG1 . THR B 1 466 ? -33.50400 -20.91400 -57.12600 1.000 52.06270  ? 466 THR B OG1 1 
ATOM   7148 C CG2 . THR B 1 466 ? -35.79600 -20.81100 -56.38500 1.000 41.15356  ? 466 THR B CG2 1 
ATOM   7149 N N   . VAL B 1 467 ? -36.14200 -23.29300 -54.23700 1.000 38.25333  ? 467 VAL B N   1 
ATOM   7150 C CA  . VAL B 1 467 ? -37.27400 -24.09000 -53.79400 1.000 43.67484  ? 467 VAL B CA  1 
ATOM   7151 C C   . VAL B 1 467 ? -38.54800 -23.38400 -54.23200 1.000 43.22522  ? 467 VAL B C   1 
ATOM   7152 O O   . VAL B 1 467 ? -38.71500 -22.17900 -53.99500 1.000 40.62851  ? 467 VAL B O   1 
ATOM   7153 C CB  . VAL B 1 467 ? -37.24600 -24.29300 -52.26700 1.000 49.27172  ? 467 VAL B CB  1 
ATOM   7154 C CG1 . VAL B 1 467 ? -38.32800 -25.27500 -51.83100 1.000 44.84996  ? 467 VAL B CG1 1 
ATOM   7155 C CG2 . VAL B 1 467 ? -35.86400 -24.77100 -51.82000 1.000 45.19878  ? 467 VAL B CG2 1 
ATOM   7156 N N   . ARG B 1 468 ? -39.43900 -24.12800 -54.87700 1.000 39.02628  ? 468 ARG B N   1 
ATOM   7157 C CA  . ARG B 1 468 ? -40.70400 -23.59700 -55.36000 1.000 43.60964  ? 468 ARG B CA  1 
ATOM   7158 C C   . ARG B 1 468 ? -41.84900 -24.36900 -54.72500 1.000 42.26797  ? 468 ARG B C   1 
ATOM   7159 O O   . ARG B 1 468 ? -41.65700 -25.45000 -54.17000 1.000 44.49557  ? 468 ARG B O   1 
ATOM   7160 C CB  . ARG B 1 468 ? -40.81100 -23.68400 -56.89600 1.000 42.45974  ? 468 ARG B CB  1 
ATOM   7161 C CG  . ARG B 1 468 ? -39.67700 -22.98500 -57.66100 1.000 38.95770  ? 468 ARG B CG  1 
ATOM   7162 C CD  . ARG B 1 468 ? -39.68900 -21.49700 -57.38900 1.000 32.00045  ? 468 ARG B CD  1 
ATOM   7163 N NE  . ARG B 1 468 ? -40.99600 -20.93800 -57.71000 1.000 36.39515  ? 468 ARG B NE  1 
ATOM   7164 C CZ  . ARG B 1 468 ? -41.33200 -20.47900 -58.90900 1.000 35.65232  ? 468 ARG B CZ  1 
ATOM   7165 N NH1 . ARG B 1 468 ? -40.46000 -20.45300 -59.90400 1.000 31.20873  ? 468 ARG B NH1 1 
ATOM   7166 N NH2 . ARG B 1 468 ? -42.57400 -20.04600 -59.11600 1.000 31.61624  ? 468 ARG B NH2 1 
ATOM   7167 N N   . ASP B 1 469 ? -43.04400 -23.78600 -54.79700 1.000 43.45652  ? 469 ASP B N   1 
ATOM   7168 C CA  . ASP B 1 469 ? -44.31100 -24.45300 -54.48600 1.000 48.97178  ? 469 ASP B CA  1 
ATOM   7169 C C   . ASP B 1 469 ? -44.48300 -24.77000 -53.00500 1.000 44.96004  ? 469 ASP B C   1 
ATOM   7170 O O   . ASP B 1 469 ? -45.37700 -25.54400 -52.64300 1.000 45.72684  ? 469 ASP B O   1 
ATOM   7171 C CB  . ASP B 1 469 ? -44.48600 -25.72800 -55.31900 1.000 51.52312  ? 469 ASP B CB  1 
ATOM   7172 C CG  . ASP B 1 469 ? -44.14800 -25.51100 -56.78500 1.000 55.27555  ? 469 ASP B CG  1 
ATOM   7173 O OD1 . ASP B 1 469 ? -44.41900 -24.39100 -57.28200 1.000 47.57957  ? 469 ASP B OD1 1 
ATOM   7174 O OD2 . ASP B 1 469 ? -43.59800 -26.44600 -57.42500 1.000 56.62807  ? 469 ASP B OD2 1 
ATOM   7175 N N   . THR B 1 470 ? -43.64800 -24.19000 -52.14100 1.000 44.07498  ? 470 THR B N   1 
ATOM   7176 C CA  . THR B 1 470 ? -43.86100 -24.18300 -50.70000 1.000 42.21401  ? 470 THR B CA  1 
ATOM   7177 C C   . THR B 1 470 ? -44.05300 -22.73900 -50.23800 1.000 44.44756  ? 470 THR B C   1 
ATOM   7178 O O   . THR B 1 470 ? -43.33400 -21.83300 -50.67600 1.000 43.65687  ? 470 THR B O   1 
ATOM   7179 C CB  . THR B 1 470 ? -42.68800 -24.84100 -49.94000 1.000 44.73486  ? 470 THR B CB  1 
ATOM   7180 O OG1 . THR B 1 470 ? -41.52700 -24.01300 -50.01200 1.000 49.46643  ? 470 THR B OG1 1 
ATOM   7181 C CG2 . THR B 1 470 ? -42.34000 -26.18100 -50.54200 1.000 49.42931  ? 470 THR B CG2 1 
ATOM   7182 N N   . SER B 1 471 ? -45.05400 -22.52400 -49.38400 1.000 45.03973  ? 471 SER B N   1 
ATOM   7183 C CA  . SER B 1 471 ? -45.37400 -21.22400 -48.81400 1.000 45.80410  ? 471 SER B CA  1 
ATOM   7184 C C   . SER B 1 471 ? -44.53700 -20.98900 -47.55900 1.000 40.88841  ? 471 SER B C   1 
ATOM   7185 O O   . SER B 1 471 ? -43.77100 -21.84900 -47.12700 1.000 43.59091  ? 471 SER B O   1 
ATOM   7186 C CB  . SER B 1 471 ? -46.86500 -21.15300 -48.47800 1.000 37.82057  ? 471 SER B CB  1 
ATOM   7187 O OG  . SER B 1 471 ? -47.17400 -22.13200 -47.49400 1.000 37.46194  ? 471 SER B OG  1 
ATOM   7188 N N   . LEU B 1 472 ? -44.69800 -19.82600 -46.94100 1.000 45.92936  ? 472 LEU B N   1 
ATOM   7189 C CA  . LEU B 1 472 ? -44.11700 -19.63900 -45.61700 1.000 45.91638  ? 472 LEU B CA  1 
ATOM   7190 C C   . LEU B 1 472 ? -44.81600 -20.56400 -44.62000 1.000 45.57668  ? 472 LEU B C   1 
ATOM   7191 O O   . LEU B 1 472 ? -46.03700 -20.76600 -44.71200 1.000 41.72559  ? 472 LEU B O   1 
ATOM   7192 C CB  . LEU B 1 472 ? -44.24000 -18.18700 -45.17000 1.000 44.91690  ? 472 LEU B CB  1 
ATOM   7193 C CG  . LEU B 1 472 ? -43.36300 -17.24300 -45.99300 1.000 52.41435  ? 472 LEU B CG  1 
ATOM   7194 C CD1 . LEU B 1 472 ? -43.85700 -15.79300 -45.94400 1.000 47.25333  ? 472 LEU B CD1 1 
ATOM   7195 C CD2 . LEU B 1 472 ? -41.92900 -17.35100 -45.51300 1.000 46.92406  ? 472 LEU B CD2 1 
ATOM   7196 N N   . PRO B 1 473 ? -44.07300 -21.14800 -43.67300 1.000 47.31677  ? 473 PRO B N   1 
ATOM   7197 C CA  . PRO B 1 473 ? -44.65800 -22.15800 -42.78800 1.000 45.52016  ? 473 PRO B CA  1 
ATOM   7198 C C   . PRO B 1 473 ? -45.61200 -21.53400 -41.79600 1.000 43.12629  ? 473 PRO B C   1 
ATOM   7199 O O   . PRO B 1 473 ? -45.43200 -20.40200 -41.34800 1.000 42.50645  ? 473 PRO B O   1 
ATOM   7200 C CB  . PRO B 1 473 ? -43.44100 -22.73300 -42.06600 1.000 47.94577  ? 473 PRO B CB  1 
ATOM   7201 C CG  . PRO B 1 473 ? -42.56600 -21.55700 -41.92200 1.000 38.79197  ? 473 PRO B CG  1 
ATOM   7202 C CD  . PRO B 1 473 ? -42.70700 -20.80700 -43.24400 1.000 44.71170  ? 473 PRO B CD  1 
ATOM   7203 N N   . TRP B 1 474 ? -46.63000 -22.29800 -41.43500 1.000 46.47990  ? 474 TRP B N   1 
ATOM   7204 C CA  . TRP B 1 474 ? -47.65800 -21.78200 -40.54300 1.000 47.65177  ? 474 TRP B CA  1 
ATOM   7205 C C   . TRP B 1 474 ? -47.10700 -21.76900 -39.12000 1.000 54.34211  ? 474 TRP B C   1 
ATOM   7206 O O   . TRP B 1 474 ? -46.88000 -22.82500 -38.51600 1.000 57.27292  ? 474 TRP B O   1 
ATOM   7207 C CB  . TRP B 1 474 ? -48.92700 -22.61100 -40.69300 1.000 42.71191  ? 474 TRP B CB  1 
ATOM   7208 C CG  . TRP B 1 474 ? -49.40200 -22.54800 -42.10300 1.000 42.12212  ? 474 TRP B CG  1 
ATOM   7209 C CD1 . TRP B 1 474 ? -49.07800 -23.40500 -43.12900 1.000 42.92191  ? 474 TRP B CD1 1 
ATOM   7210 C CD2 . TRP B 1 474 ? -50.24600 -21.54500 -42.66800 1.000 38.50645  ? 474 TRP B CD2 1 
ATOM   7211 N NE1 . TRP B 1 474 ? -49.69600 -22.99800 -44.29300 1.000 39.60552  ? 474 TRP B NE1 1 
ATOM   7212 C CE2 . TRP B 1 474 ? -50.42000 -21.86200 -44.03600 1.000 35.91356  ? 474 TRP B CE2 1 
ATOM   7213 C CE3 . TRP B 1 474 ? -50.88500 -20.41400 -42.14900 1.000 34.91730  ? 474 TRP B CE3 1 
ATOM   7214 C CZ2 . TRP B 1 474 ? -51.20100 -21.08600 -44.88600 1.000 35.72441  ? 474 TRP B CZ2 1 
ATOM   7215 C CZ3 . TRP B 1 474 ? -51.65800 -19.63700 -43.00100 1.000 33.13895  ? 474 TRP B CZ3 1 
ATOM   7216 C CH2 . TRP B 1 474 ? -51.81700 -19.98000 -44.34800 1.000 36.62591  ? 474 TRP B CH2 1 
ATOM   7217 N N   . LYS B 1 475 ? -46.86100 -20.56900 -38.59800 1.000 48.26300  ? 475 LYS B N   1 
ATOM   7218 C CA  . LYS B 1 475 ? -46.28800 -20.42800 -37.27300 1.000 49.52989  ? 475 LYS B CA  1 
ATOM   7219 C C   . LYS B 1 475 ? -47.32100 -20.76400 -36.19600 1.000 48.33529  ? 475 LYS B C   1 
ATOM   7220 O O   . LYS B 1 475 ? -48.52300 -20.91100 -36.45600 1.000 45.31769  ? 475 LYS B O   1 
ATOM   7221 C CB  . LYS B 1 475 ? -45.73800 -19.01400 -37.08700 1.000 50.51297  ? 475 LYS B CB  1 
ATOM   7222 C CG  . LYS B 1 475 ? -44.38300 -18.80100 -37.77300 1.000 57.18965  ? 475 LYS B CG  1 
ATOM   7223 C CD  . LYS B 1 475 ? -43.34600 -19.85000 -37.30900 1.000 57.54812  ? 475 LYS B CD  1 
ATOM   7224 C CE  . LYS B 1 475 ? -42.32400 -19.27900 -36.29200 1.000 67.77053  ? 475 LYS B CE  1 
ATOM   7225 N NZ  . LYS B 1 475 ? -41.66600 -20.34700 -35.46000 1.000 54.14942  ? 475 LYS B NZ  1 
ATOM   7226 N N   . ARG B 1 476 ? -46.82700 -20.88900 -34.96000 1.000 49.21234  ? 476 ARG B N   1 
ATOM   7227 C CA  . ARG B 1 476 ? -47.69400 -21.24700 -33.84200 1.000 46.41438  ? 476 ARG B CA  1 
ATOM   7228 C C   . ARG B 1 476 ? -48.74400 -20.16700 -33.57800 1.000 48.46810  ? 476 ARG B C   1 
ATOM   7229 O O   . ARG B 1 476 ? -49.87700 -20.48400 -33.19500 1.000 42.70801  ? 476 ARG B O   1 
ATOM   7230 C CB  . ARG B 1 476 ? -46.83600 -21.51700 -32.60600 1.000 50.62945  ? 476 ARG B CB  1 
ATOM   7231 C CG  . ARG B 1 476 ? -47.59700 -21.60500 -31.30300 1.000 56.94662  ? 476 ARG B CG  1 
ATOM   7232 C CD  . ARG B 1 476 ? -46.75900 -21.04300 -30.15000 1.000 66.89799  ? 476 ARG B CD  1 
ATOM   7233 N NE  . ARG B 1 476 ? -47.59600 -20.38900 -29.14800 1.000 67.44606  ? 476 ARG B NE  1 
ATOM   7234 C CZ  . ARG B 1 476 ? -48.10100 -19.16800 -29.27100 1.000 63.81392  ? 476 ARG B CZ  1 
ATOM   7235 N NH1 . ARG B 1 476 ? -47.86100 -18.41800 -30.33800 1.000 62.29978  ? 476 ARG B NH1 1 
ATOM   7236 N NH2 . ARG B 1 476 ? -48.87400 -18.68900 -28.30400 1.000 66.13938  ? 476 ARG B NH2 1 
ATOM   7237 N N   . ALA B 1 477 ? -48.40200 -18.89500 -33.81700 1.000 47.81645  ? 477 ALA B N   1 
ATOM   7238 C CA  . ALA B 1 477 ? -49.37800 -17.82700 -33.64600 1.000 40.84582  ? 477 ALA B CA  1 
ATOM   7239 C C   . ALA B 1 477 ? -50.47500 -17.89800 -34.71000 1.000 45.94759  ? 477 ALA B C   1 
ATOM   7240 O O   . ALA B 1 477 ? -51.65600 -17.64900 -34.41700 1.000 41.76865  ? 477 ALA B O   1 
ATOM   7241 C CB  . ALA B 1 477 ? -48.67500 -16.47200 -33.67400 1.000 38.16723  ? 477 ALA B CB  1 
ATOM   7242 N N   . ASP B 1 478 ? -50.10200 -18.23100 -35.95100 1.000 42.89859  ? 478 ASP B N   1 
ATOM   7243 C CA  . ASP B 1 478 ? -51.09600 -18.37800 -37.01300 1.000 40.78585  ? 478 ASP B CA  1 
ATOM   7244 C C   . ASP B 1 478 ? -52.13700 -19.42000 -36.62500 1.000 41.54566  ? 478 ASP B C   1 
ATOM   7245 O O   . ASP B 1 478 ? -53.35000 -19.19400 -36.75000 1.000 36.09009  ? 478 ASP B O   1 
ATOM   7246 C CB  . ASP B 1 478 ? -50.41300 -18.76800 -38.33700 1.000 38.01111  ? 478 ASP B CB  1 
ATOM   7247 C CG  . ASP B 1 478 ? -49.29500 -17.79200 -38.75500 1.000 41.10666  ? 478 ASP B CG  1 
ATOM   7248 O OD1 . ASP B 1 478 ? -49.47300 -16.54900 -38.66000 1.000 36.70815  ? 478 ASP B OD1 1 
ATOM   7249 O OD2 . ASP B 1 478 ? -48.22200 -18.28700 -39.17400 1.000 42.24198  ? 478 ASP B OD2 1 
ATOM   7250 N N   . LEU B 1 479 ? -51.67000 -20.56400 -36.12000 1.000 43.06448  ? 479 LEU B N   1 
ATOM   7251 C CA  . LEU B 1 479 ? -52.57600 -21.61300 -35.67800 1.000 40.41516  ? 479 LEU B CA  1 
ATOM   7252 C C   . LEU B 1 479 ? -53.48500 -21.12000 -34.56200 1.000 38.42668  ? 479 LEU B C   1 
ATOM   7253 O O   . LEU B 1 479 ? -54.70800 -21.27100 -34.63100 1.000 47.40246  ? 479 LEU B O   1 
ATOM   7254 C CB  . LEU B 1 479 ? -51.76900 -22.83500 -35.24000 1.000 41.45214  ? 479 LEU B CB  1 
ATOM   7255 C CG  . LEU B 1 479 ? -51.43500 -23.76800 -36.40600 1.000 41.36016  ? 479 LEU B CG  1 
ATOM   7256 C CD1 . LEU B 1 479 ? -50.67500 -25.02300 -35.96900 1.000 37.34336  ? 479 LEU B CD1 1 
ATOM   7257 C CD2 . LEU B 1 479 ? -52.73700 -24.15100 -37.13300 1.000 46.79749  ? 479 LEU B CD2 1 
ATOM   7258 N N   . GLY B 1 480 ? -52.91000 -20.50400 -33.53500 1.000 42.33079  ? 480 GLY B N   1 
ATOM   7259 C CA  . GLY B 1 480 ? -53.72000 -20.03900 -32.42300 1.000 37.78022  ? 480 GLY B CA  1 
ATOM   7260 C C   . GLY B 1 480 ? -54.73100 -18.99800 -32.84300 1.000 35.97287  ? 480 GLY B C   1 
ATOM   7261 O O   . GLY B 1 480 ? -55.86100 -18.97300 -32.33900 1.000 39.39690  ? 480 GLY B O   1 
ATOM   7262 N N   . ALA B 1 481 ? -54.34400 -18.12700 -33.77600 1.000 34.22800  ? 481 ALA B N   1 
ATOM   7263 C CA  . ALA B 1 481 ? -55.28300 -17.13700 -34.28800 1.000 36.46069  ? 481 ALA B CA  1 
ATOM   7264 C C   . ALA B 1 481 ? -56.42100 -17.81500 -35.01800 1.000 40.22271  ? 481 ALA B C   1 
ATOM   7265 O O   . ALA B 1 481 ? -57.57600 -17.36900 -34.95600 1.000 38.60207  ? 481 ALA B O   1 
ATOM   7266 C CB  . ALA B 1 481 ? -54.57200 -16.16500 -35.22300 1.000 40.04028  ? 481 ALA B CB  1 
ATOM   7267 N N   . ALA B 1 482 ? -56.10300 -18.88800 -35.73400 1.000 40.31296  ? 482 ALA B N   1 
ATOM   7268 C CA  . ALA B 1 482 ? -57.11900 -19.62100 -36.46000 1.000 33.32627  ? 482 ALA B CA  1 
ATOM   7269 C C   . ALA B 1 482 ? -58.10200 -20.26300 -35.49400 1.000 43.01107  ? 482 ALA B C   1 
ATOM   7270 O O   . ALA B 1 482 ? -59.32300 -20.16400 -35.67600 1.000 43.20505  ? 482 ALA B O   1 
ATOM   7271 C CB  . ALA B 1 482 ? -56.45100 -20.66100 -37.34500 1.000 35.10904  ? 482 ALA B CB  1 
ATOM   7272 N N   . GLU B 1 483 ? -57.58500 -20.90500 -34.44200 1.000 39.88399  ? 483 GLU B N   1 
ATOM   7273 C CA  . GLU B 1 483 ? -58.45700 -21.48500 -33.42800 1.000 40.78876  ? 483 GLU B CA  1 
ATOM   7274 C C   . GLU B 1 483 ? -59.40800 -20.44400 -32.86100 1.000 38.92017  ? 483 GLU B C   1 
ATOM   7275 O O   . GLU B 1 483 ? -60.59400 -20.71700 -32.66500 1.000 45.28082  ? 483 GLU B O   1 
ATOM   7276 C CB  . GLU B 1 483 ? -57.61700 -22.10100 -32.31200 1.000 38.79168  ? 483 GLU B CB  1 
ATOM   7277 C CG  . GLU B 1 483 ? -57.10300 -23.48900 -32.61200 1.000 47.28083  ? 483 GLU B CG  1 
ATOM   7278 C CD  . GLU B 1 483 ? -58.24000 -24.48100 -32.82700 1.000 64.74124  ? 483 GLU B CD  1 
ATOM   7279 O OE1 . GLU B 1 483 ? -59.08700 -24.62800 -31.90300 1.000 62.22292  ? 483 GLU B OE1 1 
ATOM   7280 O OE2 . GLU B 1 483 ? -58.28900 -25.10000 -33.92400 1.000 58.36687  ? 483 GLU B OE2 1 
ATOM   7281 N N   . GLY B 1 484 ? -58.90600 -19.23800 -32.60700 1.000 37.37153  ? 484 GLY B N   1 
ATOM   7282 C CA  . GLY B 1 484 ? -59.73800 -18.22200 -31.98800 1.000 34.30052  ? 484 GLY B CA  1 
ATOM   7283 C C   . GLY B 1 484 ? -60.81800 -17.71100 -32.91600 1.000 42.25708  ? 484 GLY B C   1 
ATOM   7284 O O   . GLY B 1 484 ? -61.95500 -17.48800 -32.49000 1.000 45.91242  ? 484 GLY B O   1 
ATOM   7285 N N   . PHE B 1 485 ? -60.47600 -17.49800 -34.19500 1.000 48.63385  ? 485 PHE B N   1 
ATOM   7286 C CA  . PHE B 1 485 ? -61.47900 -17.08000 -35.17400 1.000 44.67849  ? 485 PHE B CA  1 
ATOM   7287 C C   . PHE B 1 485 ? -62.62300 -18.08700 -35.21400 1.000 44.17429  ? 485 PHE B C   1 
ATOM   7288 O O   . PHE B 1 485 ? -63.80100 -17.72200 -35.10900 1.000 46.63326  ? 485 PHE B O   1 
ATOM   7289 C CB  . PHE B 1 485 ? -60.82100 -16.91300 -36.55100 1.000 41.29238  ? 485 PHE B CB  1 
ATOM   7290 C CG  . PHE B 1 485 ? -61.73300 -16.33000 -37.60500 1.000 43.65118  ? 485 PHE B CG  1 
ATOM   7291 C CD1 . PHE B 1 485 ? -62.02700 -14.97200 -37.62400 1.000 43.03306  ? 485 PHE B CD1 1 
ATOM   7292 C CD2 . PHE B 1 485 ? -62.28900 -17.14300 -38.58600 1.000 47.79640  ? 485 PHE B CD2 1 
ATOM   7293 C CE1 . PHE B 1 485 ? -62.86600 -14.43500 -38.59100 1.000 39.88531  ? 485 PHE B CE1 1 
ATOM   7294 C CE2 . PHE B 1 485 ? -63.12100 -16.61200 -39.56200 1.000 42.31985  ? 485 PHE B CE2 1 
ATOM   7295 C CZ  . PHE B 1 485 ? -63.41500 -15.25500 -39.55900 1.000 43.72292  ? 485 PHE B CZ  1 
ATOM   7296 N N   . ARG B 1 486 ? -62.27700 -19.37200 -35.30100 1.000 43.56320  ? 486 ARG B N   1 
ATOM   7297 C CA  . ARG B 1 486 ? -63.24400 -20.45000 -35.12900 1.000 44.65853  ? 486 ARG B CA  1 
ATOM   7298 C C   . ARG B 1 486 ? -64.04500 -20.29800 -33.83700 1.000 48.22213  ? 486 ARG B C   1 
ATOM   7299 O O   . ARG B 1 486 ? -65.25000 -20.57300 -33.80600 1.000 49.55861  ? 486 ARG B O   1 
ATOM   7300 C CB  . ARG B 1 486 ? -62.50900 -21.79200 -35.15300 1.000 38.98131  ? 486 ARG B CB  1 
ATOM   7301 C CG  . ARG B 1 486 ? -63.31600 -22.94300 -34.62000 1.000 42.73936  ? 486 ARG B CG  1 
ATOM   7302 C CD  . ARG B 1 486 ? -62.52200 -24.22700 -34.60900 1.000 47.22278  ? 486 ARG B CD  1 
ATOM   7303 N NE  . ARG B 1 486 ? -63.25600 -25.26500 -33.90000 1.000 53.67140  ? 486 ARG B NE  1 
ATOM   7304 C CZ  . ARG B 1 486 ? -63.22200 -25.44200 -32.58700 1.000 52.99293  ? 486 ARG B CZ  1 
ATOM   7305 N NH1 . ARG B 1 486 ? -62.45800 -24.69400 -31.80400 1.000 56.53421  ? 486 ARG B NH1 1 
ATOM   7306 N NH2 . ARG B 1 486 ? -63.96900 -26.39500 -32.04500 1.000 52.33490  ? 486 ARG B NH2 1 
ATOM   7307 N N   . GLY B 1 487 ? -63.39700 -19.85700 -32.75700 1.000 49.29149  ? 487 GLY B N   1 
ATOM   7308 C CA  . GLY B 1 487 ? -64.10500 -19.71800 -31.49500 1.000 44.59850  ? 487 GLY B CA  1 
ATOM   7309 C C   . GLY B 1 487 ? -65.24200 -18.71900 -31.55100 1.000 44.28192  ? 487 GLY B C   1 
ATOM   7310 O O   . GLY B 1 487 ? -66.25500 -18.88300 -30.86600 1.000 48.42198  ? 487 GLY B O   1 
ATOM   7311 N N   . ALA B 1 488 ? -65.14200 -17.73900 -32.44100 1.000 48.77306  ? 488 ALA B N   1 
ATOM   7312 C CA  . ALA B 1 488 ? -66.15300 -16.66200 -32.48000 1.000 49.70322  ? 488 ALA B CA  1 
ATOM   7313 C C   . ALA B 1 488 ? -67.07900 -16.76800 -33.69400 1.000 56.90436  ? 488 ALA B C   1 
ATOM   7314 O O   . ALA B 1 488 ? -67.93700 -15.89400 -33.84300 1.000 59.15157  ? 488 ALA B O   1 
ATOM   7315 C CB  . ALA B 1 488 ? -65.43900 -15.34800 -32.48700 1.000 54.19162  ? 488 ALA B CB  1 
ATOM   7316 N N   . LEU B 1 489 ? -66.90200 -17.78600 -34.52900 1.000 58.82078  ? 489 LEU B N   1 
ATOM   7317 C CA  . LEU B 1 489 ? -67.74300 -17.94900 -35.74500 1.000 58.91686  ? 489 LEU B CA  1 
ATOM   7318 C C   . LEU B 1 489 ? -68.60600 -19.21200 -35.62100 1.000 58.52001  ? 489 LEU B C   1 
ATOM   7319 O O   . LEU B 1 489 ? -68.94500 -19.78300 -36.65700 1.000 64.71404  ? 489 LEU B O   1 
ATOM   7320 C CB  . LEU B 1 489 ? -66.81800 -18.01500 -36.96400 1.000 51.77802  ? 489 LEU B CB  1 
ATOM   7321 C CG  . LEU B 1 489 ? -67.26900 -17.25400 -38.20600 1.000 54.75133  ? 489 LEU B CG  1 
ATOM   7322 C CD1 . LEU B 1 489 ? -67.08500 -15.75800 -38.02600 1.000 59.36792  ? 489 LEU B CD1 1 
ATOM   7323 C CD2 . LEU B 1 489 ? -66.50400 -17.73200 -39.42600 1.000 55.86090  ? 489 LEU B CD2 1 
ATOM   7324 N N   . VAL B 1 490 ? -68.94900 -19.62000 -34.39400 1.000 57.52785  ? 490 VAL B N   1 
ATOM   7325 C CA  . VAL B 1 490 ? -69.79000 -20.83400 -34.17200 1.000 64.68629  ? 490 VAL B CA  1 
ATOM   7326 C C   . VAL B 1 490 ? -71.14400 -20.40700 -33.59900 1.000 62.15926  ? 490 VAL B C   1 
ATOM   7327 O O   . VAL B 1 490 ? -71.25100 -19.23100 -33.22200 1.000 67.59631  ? 490 VAL B O   1 
ATOM   7328 C CB  . VAL B 1 490 ? -69.09700 -21.85500 -33.25400 1.000 61.41005  ? 490 VAL B CB  1 
ATOM   7329 C CG1 . VAL B 1 490 ? -67.98600 -22.59900 -33.97400 1.000 60.34966  ? 490 VAL B CG1 1 
ATOM   7330 C CG2 . VAL B 1 490 ? -68.58500 -21.21600 -31.97400 1.000 57.06444  ? 490 VAL B CG2 1 
HETATM 7331 C CHA . BLA C 2 .   ? -31.09800 2.57100   1.88900   1.000 27.96734  ? 501 BLA A CHA 1 
HETATM 7332 N NA  . BLA C 2 .   ? -32.50000 0.68000   2.86400   1.000 28.49930  ? 501 BLA A NA  1 
HETATM 7333 C C1A . BLA C 2 .   ? -31.50900 1.13200   2.08000   1.000 27.95529  ? 501 BLA A C1A 1 
HETATM 7334 C C2A . BLA C 2 .   ? -30.90200 0.06900   1.48700   1.000 29.62933  ? 501 BLA A C2A 1 
HETATM 7335 C C3A . BLA C 2 .   ? -31.53700 -1.04900  1.89800   1.000 31.05254  ? 501 BLA A C3A 1 
HETATM 7336 C C4A . BLA C 2 .   ? -32.54200 -0.66500  2.76000   1.000 29.23557  ? 501 BLA A C4A 1 
HETATM 7337 C CMA . BLA C 2 .   ? -31.16300 -2.46100  1.42400   1.000 31.93395  ? 501 BLA A CMA 1 
HETATM 7338 C CAA . BLA C 2 .   ? -29.72000 0.13800   0.50500   1.000 30.73395  ? 501 BLA A CAA 1 
HETATM 7339 C CBA . BLA C 2 .   ? -28.35000 0.10900   1.21700   1.000 32.32698  ? 501 BLA A CBA 1 
HETATM 7340 C CGA . BLA C 2 .   ? -27.98200 -1.25900  1.79700   1.000 24.15446  ? 501 BLA A CGA 1 
HETATM 7341 O O1A . BLA C 2 .   ? -27.71200 -1.37400  3.01300   1.000 34.60609  ? 501 BLA A O1A 1 
HETATM 7342 O O2A . BLA C 2 .   ? -27.96600 -2.29400  1.09700   1.000 24.88005  ? 501 BLA A O2A 1 
HETATM 7343 C CHB . BLA C 2 .   ? -33.57700 -1.50000  3.51100   1.000 33.38705  ? 501 BLA A CHB 1 
HETATM 7344 N NB  . BLA C 2 .   ? -32.15400 -3.53600  4.05600   1.000 35.93436  ? 501 BLA A NB  1 
HETATM 7345 C C1B . BLA C 2 .   ? -33.45100 -2.77600  3.76900   1.000 33.07678  ? 501 BLA A C1B 1 
HETATM 7346 C C2B . BLA C 2 .   ? -34.55200 -3.77700  3.81900   1.000 31.40950  ? 501 BLA A C2B 1 
HETATM 7347 C C3B . BLA C 2 .   ? -34.02400 -5.05900  4.11000   1.000 34.25054  ? 501 BLA A C3B 1 
HETATM 7348 C C4B . BLA C 2 .   ? -32.53800 -4.99800  4.28400   1.000 36.46855  ? 501 BLA A C4B 1 
HETATM 7349 C CMB . BLA C 2 .   ? -36.02900 -3.44500  3.57400   1.000 32.36821  ? 501 BLA A CMB 1 
HETATM 7350 O OB  . BLA C 2 .   ? -31.78600 -5.88500  4.53400   1.000 39.18464  ? 501 BLA A OB  1 
HETATM 7351 C CAB . BLA C 2 .   ? -34.84300 -6.33700  4.23800   1.000 34.18510  ? 501 BLA A CAB 1 
HETATM 7352 C CBB . BLA C 2 .   ? -34.35600 -7.34400  4.94000   1.000 36.18811  ? 501 BLA A CBB 1 
HETATM 7353 N NC  . BLA C 2 .   ? -34.91200 4.21200   5.92300   1.000 33.02947  ? 501 BLA A NC  1 
HETATM 7354 C C1C . BLA C 2 .   ? -36.03600 4.22100   6.96800   1.000 33.34685  ? 501 BLA A C1C 1 
HETATM 7355 C C2C . BLA C 2 .   ? -36.54500 5.63100   7.06100   1.000 36.89844  ? 501 BLA A C2C 1 
HETATM 7356 C C3C . BLA C 2 .   ? -35.73500 6.48800   6.08300   1.000 37.82878  ? 501 BLA A C3C 1 
HETATM 7357 C C4C . BLA C 2 .   ? -34.74800 5.62900   5.38400   1.000 31.14775  ? 501 BLA A C4C 1 
HETATM 7358 C CMC . BLA C 2 .   ? -36.38200 6.16500   8.49200   1.000 37.73739  ? 501 BLA A CMC 1 
HETATM 7359 O OC  . BLA C 2 .   ? -36.42200 3.26800   7.56700   1.000 35.35123  ? 501 BLA A OC  1 
HETATM 7360 C CAC . BLA C 2 .   ? -35.83700 7.79600   5.85300   1.000 38.12953  ? 501 BLA A CAC 1 
HETATM 7361 C CBC . BLA C 2 .   ? -36.94000 8.66900   6.39100   1.000 41.81677  ? 501 BLA A CBC 1 
HETATM 7362 C CHD . BLA C 2 .   ? -33.91500 6.07700   4.49600   1.000 33.91827  ? 501 BLA A CHD 1 
HETATM 7363 N ND  . BLA C 2 .   ? -32.75100 3.82000   3.47100   1.000 31.83968  ? 501 BLA A ND  1 
HETATM 7364 C C1D . BLA C 2 .   ? -32.98600 5.28400   3.59700   1.000 30.67205  ? 501 BLA A C1D 1 
HETATM 7365 C C2D . BLA C 2 .   ? -32.12900 6.02500   2.65700   1.000 28.10541  ? 501 BLA A C2D 1 
HETATM 7366 C C3D . BLA C 2 .   ? -31.33500 5.04000   1.92200   1.000 30.46738  ? 501 BLA A C3D 1 
HETATM 7367 C C4D . BLA C 2 .   ? -31.68800 3.63900   2.39500   1.000 32.74757  ? 501 BLA A C4D 1 
HETATM 7368 C CMD . BLA C 2 .   ? -32.10400 7.55300   2.52700   1.000 27.69066  ? 501 BLA A CMD 1 
HETATM 7369 C CAD . BLA C 2 .   ? -30.29300 5.32300   0.84700   1.000 28.00683  ? 501 BLA A CAD 1 
HETATM 7370 C CBD . BLA C 2 .   ? -28.92600 4.96800   1.42900   1.000 29.22447  ? 501 BLA A CBD 1 
HETATM 7371 C CGD . BLA C 2 .   ? -27.89800 5.58400   0.48900   1.000 35.37708  ? 501 BLA A CGD 1 
HETATM 7372 O O1D . BLA C 2 .   ? -27.56600 4.96900   -0.58400  1.000 29.29103  ? 501 BLA A O1D 1 
HETATM 7373 O O2D . BLA C 2 .   ? -27.41600 6.72300   0.80300   1.000 30.76105  ? 501 BLA A O2D 1 
HETATM 7374 C C1  . BEN D 3 .   ? -55.51100 -16.41000 -27.05700 1.000 90.15124  ? 502 BEN A C1  1 
HETATM 7375 C C2  . BEN D 3 .   ? -56.58400 -15.53400 -26.80400 1.000 80.49908  ? 502 BEN A C2  1 
HETATM 7376 C C3  . BEN D 3 .   ? -57.78100 -15.64600 -27.51100 1.000 73.98386  ? 502 BEN A C3  1 
HETATM 7377 C C4  . BEN D 3 .   ? -57.91900 -16.63800 -28.48000 1.000 74.33332  ? 502 BEN A C4  1 
HETATM 7378 C C5  . BEN D 3 .   ? -56.86000 -17.51200 -28.73600 1.000 74.05989  ? 502 BEN A C5  1 
HETATM 7379 C C6  . BEN D 3 .   ? -55.66300 -17.40500 -28.03200 1.000 75.42472  ? 502 BEN A C6  1 
HETATM 7380 C C   . BEN D 3 .   ? -54.22400 -16.28900 -26.28700 1.000 86.20650  ? 502 BEN A C   1 
HETATM 7381 N N1  . BEN D 3 .   ? -53.11800 -16.88400 -26.57900 1.000 72.60017  ? 502 BEN A N1  1 
HETATM 7382 N N2  . BEN D 3 .   ? -54.30400 -15.47000 -25.19200 1.000 76.08796  ? 502 BEN A N2  1 
HETATM 7383 C CHA . BLA E 2 .   ? -18.60800 -35.30000 -36.98000 1.000 28.09023  ? 501 BLA B CHA 1 
HETATM 7384 N NA  . BLA E 2 .   ? -19.36500 -33.39700 -38.50600 1.000 36.07665  ? 501 BLA B NA  1 
HETATM 7385 C C1A . BLA E 2 .   ? -18.95700 -33.85900 -37.31200 1.000 33.01441  ? 501 BLA B C1A 1 
HETATM 7386 C C2A . BLA E 2 .   ? -18.86700 -32.79600 -36.44800 1.000 28.30315  ? 501 BLA B C2A 1 
HETATM 7387 C C3A . BLA E 2 .   ? -19.23500 -31.68200 -37.10900 1.000 32.76476  ? 501 BLA B C3A 1 
HETATM 7388 C C4A . BLA E 2 .   ? -19.54600 -32.06800 -38.39700 1.000 31.55843  ? 501 BLA B C4A 1 
HETATM 7389 C CMA . BLA E 2 .   ? -19.28700 -30.27900 -36.48900 1.000 30.76608  ? 501 BLA B CMA 1 
HETATM 7390 C CAA . BLA E 2 .   ? -18.43300 -32.87400 -34.99000 1.000 26.95454  ? 501 BLA B CAA 1 
HETATM 7391 C CBA . BLA E 2 .   ? -16.89900 -32.98900 -34.92400 1.000 29.37110  ? 501 BLA B CBA 1 
HETATM 7392 C CGA . BLA E 2 .   ? -16.30500 -31.59500 -35.03100 1.000 28.96093  ? 501 BLA B CGA 1 
HETATM 7393 O O1A . BLA E 2 .   ? -15.46000 -31.32500 -35.92000 1.000 34.40997  ? 501 BLA B O1A 1 
HETATM 7394 O O2A . BLA E 2 .   ? -16.69200 -30.69000 -34.25800 1.000 30.43966  ? 501 BLA B O2A 1 
HETATM 7395 C CHB . BLA E 2 .   ? -20.02900 -31.24700 -39.56800 1.000 30.33539  ? 501 BLA B CHB 1 
HETATM 7396 N NB  . BLA E 2 .   ? -18.43800 -29.28400 -39.26100 1.000 35.48766  ? 501 BLA B NB  1 
HETATM 7397 C C1B . BLA E 2 .   ? -19.68900 -30.01100 -39.76100 1.000 31.12398  ? 501 BLA B C1B 1 
HETATM 7398 C C2B . BLA E 2 .   ? -20.49300 -29.03900 -40.54900 1.000 36.79842  ? 501 BLA B C2B 1 
HETATM 7399 C C3B . BLA E 2 .   ? -19.82700 -27.79400 -40.55200 1.000 32.96428  ? 501 BLA B C3B 1 
HETATM 7400 C C4B . BLA E 2 .   ? -18.55100 -27.84600 -39.78500 1.000 36.24136  ? 501 BLA B C4B 1 
HETATM 7401 C CMB . BLA E 2 .   ? -21.84500 -29.35800 -41.23000 1.000 29.79117  ? 501 BLA B CMB 1 
HETATM 7402 O OB  . BLA E 2 .   ? -17.78500 -26.95100 -39.61800 1.000 37.40851  ? 501 BLA B OB  1 
HETATM 7403 C CAB . BLA E 2 .   ? -20.34800 -26.54800 -41.23300 1.000 32.80106  ? 501 BLA B CAB 1 
HETATM 7404 C CBB . BLA E 2 .   ? -20.17300 -25.41000 -40.61000 1.000 33.26652  ? 501 BLA B CBB 1 
HETATM 7405 N NC  . BLA E 2 .   ? -19.63100 -36.89400 -42.27700 1.000 37.69339  ? 501 BLA B NC  1 
HETATM 7406 C C1C . BLA E 2 .   ? -19.94400 -36.84200 -43.77800 1.000 41.71932  ? 501 BLA B C1C 1 
HETATM 7407 C C2C . BLA E 2 .   ? -20.29200 -38.23300 -44.21700 1.000 39.28861  ? 501 BLA B C2C 1 
HETATM 7408 C C3C . BLA E 2 .   ? -20.18300 -39.13700 -42.99400 1.000 36.85206  ? 501 BLA B C3C 1 
HETATM 7409 C C4C . BLA E 2 .   ? -19.80000 -38.33700 -41.81200 1.000 35.13620  ? 501 BLA B C4C 1 
HETATM 7410 C CMC . BLA E 2 .   ? -19.34800 -38.65600 -45.34900 1.000 39.01481  ? 501 BLA B CMC 1 
HETATM 7411 O OC  . BLA E 2 .   ? -19.90900 -35.85900 -44.45400 1.000 45.00050  ? 501 BLA B OC  1 
HETATM 7412 C CAC . BLA E 2 .   ? -20.40400 -40.43700 -42.88900 1.000 41.07361  ? 501 BLA B CAC 1 
HETATM 7413 C CBC . BLA E 2 .   ? -20.55900 -41.38200 -44.04000 1.000 48.24499  ? 501 BLA B CBC 1 
HETATM 7414 C CHD . BLA E 2 .   ? -19.63000 -38.83800 -40.61800 1.000 33.96865  ? 501 BLA B CHD 1 
HETATM 7415 N ND  . BLA E 2 .   ? -19.13600 -36.59100 -39.16500 1.000 29.28956  ? 501 BLA B ND  1 
HETATM 7416 C C1D . BLA E 2 .   ? -19.32300 -38.06300 -39.34900 1.000 31.67522  ? 501 BLA B C1D 1 
HETATM 7417 C C2D . BLA E 2 .   ? -19.14600 -38.77600 -38.05500 1.000 33.91432  ? 501 BLA B C2D 1 
HETATM 7418 C C3D . BLA E 2 .   ? -18.84800 -37.76300 -37.06000 1.000 30.39327  ? 501 BLA B C3D 1 
HETATM 7419 C C4D . BLA E 2 .   ? -18.83800 -36.38000 -37.69700 1.000 29.37653  ? 501 BLA B C4D 1 
HETATM 7420 C CMD . BLA E 2 .   ? -19.23100 -40.28300 -37.78600 1.000 23.35765  ? 501 BLA B CMD 1 
HETATM 7421 C CAD . BLA E 2 .   ? -18.60500 -38.04600 -35.58900 1.000 30.04164  ? 501 BLA B CAD 1 
HETATM 7422 C CBD . BLA E 2 .   ? -17.13300 -37.81200 -35.27000 1.000 28.62147  ? 501 BLA B CBD 1 
HETATM 7423 C CGD . BLA E 2 .   ? -16.96500 -38.50800 -33.94300 1.000 30.98193  ? 501 BLA B CGD 1 
HETATM 7424 O O1D . BLA E 2 .   ? -17.45500 -38.00000 -32.88300 1.000 32.16111  ? 501 BLA B O1D 1 
HETATM 7425 O O2D . BLA E 2 .   ? -16.37300 -39.61100 -33.94500 1.000 31.16462  ? 501 BLA B O2D 1 
HETATM 7426 O O   . HOH F 4 .   ? -28.28600 13.80300  4.89200   1.000 40.34372  ? 601 HOH A O   1 
HETATM 7427 O O   . HOH F 4 .   ? -37.20700 -22.05300 -17.38300 1.000 56.21103  ? 602 HOH A O   1 
HETATM 7428 O O   . HOH F 4 .   ? -27.75100 -23.74700 -3.22700  1.000 47.83975  ? 603 HOH A O   1 
HETATM 7429 O O   . HOH F 4 .   ? -61.92100 4.80300   -19.91100 1.000 63.29346  ? 604 HOH A O   1 
HETATM 7430 O O   . HOH F 4 .   ? -21.57600 10.89900  -11.88700 1.000 40.25259  ? 605 HOH A O   1 
HETATM 7431 O O   . HOH F 4 .   ? -16.36400 22.32300  -15.57900 1.000 46.18730  ? 606 HOH A O   1 
HETATM 7432 O O   . HOH F 4 .   ? -78.19400 -21.76400 -17.86100 1.000 72.21176  ? 607 HOH A O   1 
HETATM 7433 O O   . HOH F 4 .   ? -58.49300 -6.43400  4.20400   1.000 42.80043  ? 608 HOH A O   1 
HETATM 7434 O O   . HOH F 4 .   ? 1.95700   12.83300  8.13700   1.000 54.31550  ? 609 HOH A O   1 
HETATM 7435 O O   . HOH F 4 .   ? -8.05800  1.81300   2.76000   1.000 46.85941  ? 610 HOH A O   1 
HETATM 7436 O O   . HOH F 4 .   ? -21.50300 10.88900  1.00900   1.000 34.53120  ? 611 HOH A O   1 
HETATM 7437 O O   . HOH F 4 .   ? -35.00500 -19.67200 1.32100   1.000 42.54546  ? 612 HOH A O   1 
HETATM 7438 O O   . HOH F 4 .   ? -14.99400 4.18400   -15.37100 1.000 54.17976  ? 613 HOH A O   1 
HETATM 7439 O O   . HOH F 4 .   ? -28.04500 -4.41700  2.12600   1.000 30.95638  ? 614 HOH A O   1 
HETATM 7440 O O   . HOH F 4 .   ? -77.07700 -26.46900 -33.08500 1.000 76.82475  ? 615 HOH A O   1 
HETATM 7441 O O   . HOH F 4 .   ? -39.57900 1.72100   16.69400  1.000 59.22488  ? 616 HOH A O   1 
HETATM 7442 O O   . HOH F 4 .   ? -17.87700 2.02700   5.15500   1.000 30.71955  ? 617 HOH A O   1 
HETATM 7443 O O   . HOH F 4 .   ? -41.29100 -33.35000 -6.82000  1.000 56.76018  ? 618 HOH A O   1 
HETATM 7444 O O   . HOH F 4 .   ? -43.20200 5.31000   -3.58300  1.000 53.04302  ? 619 HOH A O   1 
HETATM 7445 O O   . HOH F 4 .   ? -81.44600 -30.23800 -24.24000 1.000 57.79867  ? 620 HOH A O   1 
HETATM 7446 O O   . HOH F 4 .   ? -66.01500 -5.63700  1.16600   1.000 48.74970  ? 621 HOH A O   1 
HETATM 7447 O O   . HOH F 4 .   ? -67.43600 -8.02700  3.80500   1.000 46.43732  ? 622 HOH A O   1 
HETATM 7448 O O   . HOH F 4 .   ? -78.32800 -20.74400 -13.29800 1.000 54.43826  ? 623 HOH A O   1 
HETATM 7449 O O   . HOH F 4 .   ? -41.00400 -24.72900 -5.16500  1.000 73.44258  ? 624 HOH A O   1 
HETATM 7450 O O   . HOH F 4 .   ? -58.95300 -22.10900 -14.44400 1.000 43.80678  ? 625 HOH A O   1 
HETATM 7451 O O   . HOH F 4 .   ? -11.84800 5.00900   -20.51900 1.000 57.35910  ? 626 HOH A O   1 
HETATM 7452 O O   . HOH F 4 .   ? -39.77400 3.19800   6.84700   1.000 33.54236  ? 627 HOH A O   1 
HETATM 7453 O O   . HOH F 4 .   ? -39.18900 0.40300   -1.00700  1.000 31.30046  ? 628 HOH A O   1 
HETATM 7454 O O   . HOH F 4 .   ? -61.15300 -28.54700 -20.10300 1.000 58.66792  ? 629 HOH A O   1 
HETATM 7455 O O   . HOH F 4 .   ? -39.06800 -1.43000  1.22300   1.000 36.89335  ? 630 HOH A O   1 
HETATM 7456 O O   . HOH F 4 .   ? -13.79000 0.11400   9.02200   1.000 49.40798  ? 631 HOH A O   1 
HETATM 7457 O O   . HOH F 4 .   ? -7.18300  -17.55900 -4.49900  1.000 36.30467  ? 632 HOH A O   1 
HETATM 7458 O O   . HOH F 4 .   ? -37.29600 -21.07000 0.30700   1.000 47.15108  ? 633 HOH A O   1 
HETATM 7459 O O   . HOH F 4 .   ? -58.73300 -6.56700  -19.62200 1.000 47.99529  ? 634 HOH A O   1 
HETATM 7460 O O   . HOH F 4 .   ? -28.93800 -24.37100 0.21200   1.000 33.25611  ? 635 HOH A O   1 
HETATM 7461 O O   . HOH F 4 .   ? -47.74900 -15.18700 7.54500   1.000 57.29098  ? 636 HOH A O   1 
HETATM 7462 O O   . HOH F 4 .   ? -70.24300 2.88100   -18.50100 1.000 62.41464  ? 637 HOH A O   1 
HETATM 7463 O O   . HOH F 4 .   ? -18.70400 15.70300  -15.98900 1.000 40.21623  ? 638 HOH A O   1 
HETATM 7464 O O   . HOH F 4 .   ? -21.63100 -17.23500 4.87200   1.000 44.87907  ? 639 HOH A O   1 
HETATM 7465 O O   . HOH F 4 .   ? -22.72000 6.15700   -5.05100  1.000 25.65887  ? 640 HOH A O   1 
HETATM 7466 O O   . HOH F 4 .   ? -75.34500 -18.01700 -5.54800  1.000 46.58545  ? 641 HOH A O   1 
HETATM 7467 O O   . HOH F 4 .   ? -76.24500 -18.75300 -8.19600  1.000 47.11280  ? 642 HOH A O   1 
HETATM 7468 O O   . HOH F 4 .   ? -7.93500  -6.95300  -8.29700  1.000 45.80916  ? 643 HOH A O   1 
HETATM 7469 O O   . HOH F 4 .   ? -19.25400 18.47400  1.34400   1.000 38.17874  ? 644 HOH A O   1 
HETATM 7470 O O   . HOH F 4 .   ? -21.73800 14.28400  -2.29800  1.000 28.31720  ? 645 HOH A O   1 
HETATM 7471 O O   . HOH F 4 .   ? -33.11200 2.26100   5.67600   1.000 28.63997  ? 646 HOH A O   1 
HETATM 7472 O O   . HOH F 4 .   ? -36.28400 -25.41100 -16.29300 1.000 65.73292  ? 647 HOH A O   1 
HETATM 7473 O O   . HOH F 4 .   ? -75.57900 -4.34000  -6.03100  1.000 47.31630  ? 648 HOH A O   1 
HETATM 7474 O O   . HOH F 4 .   ? -23.50400 11.87900  -1.11100  1.000 30.57376  ? 649 HOH A O   1 
HETATM 7475 O O   . HOH F 4 .   ? -21.95100 -23.91500 -1.84300  1.000 63.81152  ? 650 HOH A O   1 
HETATM 7476 O O   . HOH F 4 .   ? -8.75300  6.37300   5.98500   1.000 28.31245  ? 651 HOH A O   1 
HETATM 7477 O O   . HOH F 4 .   ? -13.85700 21.42300  -16.55200 1.000 43.68115  ? 652 HOH A O   1 
HETATM 7478 O O   . HOH F 4 .   ? -14.20000 6.14400   -9.37800  1.000 37.27772  ? 653 HOH A O   1 
HETATM 7479 O O   . HOH F 4 .   ? -59.60200 -3.42600  -17.98700 1.000 50.80331  ? 654 HOH A O   1 
HETATM 7480 O O   . HOH F 4 .   ? -13.17100 2.28600   -20.67900 1.000 51.24770  ? 655 HOH A O   1 
HETATM 7481 O O   . HOH F 4 .   ? -30.36200 -7.44800  -15.18800 1.000 48.42963  ? 656 HOH A O   1 
HETATM 7482 O O   . HOH F 4 .   ? -20.22500 10.12600  -9.03000  1.000 28.85142  ? 657 HOH A O   1 
HETATM 7483 O O   . HOH F 4 .   ? -32.03900 -10.21200 14.25400  1.000 50.28714  ? 658 HOH A O   1 
HETATM 7484 O O   . HOH F 4 .   ? -24.20500 4.05700   -4.12000  1.000 32.17709  ? 659 HOH A O   1 
HETATM 7485 O O   . HOH F 4 .   ? -20.25900 1.36100   -2.94100  1.000 29.91280  ? 660 HOH A O   1 
HETATM 7486 O O   . HOH F 4 .   ? 5.19900   14.01200  -5.98700  1.000 59.36882  ? 661 HOH A O   1 
HETATM 7487 O O   . HOH F 4 .   ? -55.32500 -9.35200  -4.41100  1.000 42.87647  ? 662 HOH A O   1 
HETATM 7488 O O   . HOH F 4 .   ? -5.93100  -4.59400  -13.87800 1.000 42.33121  ? 663 HOH A O   1 
HETATM 7489 O O   . HOH F 4 .   ? -45.13500 -15.61900 -22.40200 1.000 35.32099  ? 664 HOH A O   1 
HETATM 7490 O O   . HOH F 4 .   ? -7.84100  4.56000   4.36300   1.000 41.48587  ? 665 HOH A O   1 
HETATM 7491 O O   . HOH F 4 .   ? -68.04500 -16.31100 -5.60000  1.000 33.70792  ? 666 HOH A O   1 
HETATM 7492 O O   . HOH F 4 .   ? -21.92500 6.09300   13.78000  1.000 55.96620  ? 667 HOH A O   1 
HETATM 7493 O O   . HOH F 4 .   ? -11.99900 18.26500  -16.17200 1.000 43.31827  ? 668 HOH A O   1 
HETATM 7494 O O   . HOH F 4 .   ? -19.41700 -11.98300 11.61600  1.000 47.55316  ? 669 HOH A O   1 
HETATM 7495 O O   . HOH F 4 .   ? -41.99800 -11.39800 -11.39500 1.000 63.27898  ? 670 HOH A O   1 
HETATM 7496 O O   . HOH F 4 .   ? -26.46100 2.29700   -5.56400  1.000 33.12529  ? 671 HOH A O   1 
HETATM 7497 O O   . HOH F 4 .   ? -1.873    26.099    -9.037    1.000 40.55450  ? 672 HOH A O   1 
HETATM 7498 O O   . HOH F 4 .   ? -45.58600 9.02700   14.50700  1.000 63.29061  ? 673 HOH A O   1 
HETATM 7499 O O   . HOH F 4 .   ? -64.34100 -6.08500  -1.02800  1.000 37.70094  ? 674 HOH A O   1 
HETATM 7500 O O   . HOH F 4 .   ? -45.74200 -13.04300 4.40800   1.000 51.70639  ? 675 HOH A O   1 
HETATM 7501 O O   . HOH F 4 .   ? -13.67600 11.44300  9.47300   1.000 41.59793  ? 676 HOH A O   1 
HETATM 7502 O O   . HOH F 4 .   ? -29.31300 -3.76200  4.13200   1.000 33.47398  ? 677 HOH A O   1 
HETATM 7503 O O   . HOH F 4 .   ? -46.61000 -14.41600 5.87700   1.000 60.39198  ? 678 HOH A O   1 
HETATM 7504 O O   . HOH F 4 .   ? -56.86900 -4.13500  -10.72700 1.000 45.74343  ? 679 HOH A O   1 
HETATM 7505 O O   . HOH F 4 .   ? -29.48800 -27.54500 -12.86700 1.000 80.84270  ? 680 HOH A O   1 
HETATM 7506 O O   . HOH F 4 .   ? -30.52800 -9.86100  -17.09200 1.000 46.16993  ? 681 HOH A O   1 
HETATM 7507 O O   . HOH F 4 .   ? -9.258    23.393    -8.576    1.000 48.77181  ? 682 HOH A O   1 
HETATM 7508 O O   . HOH F 4 .   ? -31.85700 -5.50200  16.79100  1.000 56.66396  ? 683 HOH A O   1 
HETATM 7509 O O   . HOH F 4 .   ? -7.45900  -6.67400  -13.01300 1.000 56.73988  ? 684 HOH A O   1 
HETATM 7510 O O   . HOH F 4 .   ? -33.74800 9.82400   3.90400   1.000 32.16515  ? 685 HOH A O   1 
HETATM 7511 O O   . HOH F 4 .   ? -81.14100 -14.85600 -7.14400  1.000 34.31240  ? 686 HOH A O   1 
HETATM 7512 O O   . HOH F 4 .   ? -66.90400 -7.01100  -1.39600  1.000 29.67630  ? 687 HOH A O   1 
HETATM 7513 O O   . HOH F 4 .   ? -41.86000 -12.22500 -8.77000  1.000 46.79739  ? 688 HOH A O   1 
HETATM 7514 O O   . HOH F 4 .   ? -40.89800 -17.54000 0.32300   1.000 40.29872  ? 689 HOH A O   1 
HETATM 7515 O O   . HOH F 4 .   ? -60.13000 -15.26600 -4.78200  1.000 33.73636  ? 690 HOH A O   1 
HETATM 7516 O O   . HOH F 4 .   ? -25.43200 -15.09800 15.77000  1.000 58.80115  ? 691 HOH A O   1 
HETATM 7517 O O   . HOH F 4 .   ? -5.68900  -13.68800 -10.73000 1.000 52.02650  ? 692 HOH A O   1 
HETATM 7518 O O   . HOH F 4 .   ? -8.00800  -11.94400 -8.67200  1.000 47.00931  ? 693 HOH A O   1 
HETATM 7519 O O   . HOH F 4 .   ? -20.28500 -12.95200 14.07500  1.000 65.57740  ? 694 HOH A O   1 
HETATM 7520 O O   . HOH F 4 .   ? -15.00800 1.82900   6.00800   1.000 30.51882  ? 695 HOH A O   1 
HETATM 7521 O O   . HOH F 4 .   ? -16.02300 -0.16800  13.63600  1.000 59.02201  ? 696 HOH A O   1 
HETATM 7522 O O   . HOH F 4 .   ? -36.19400 -8.22300  14.50300  1.000 60.89899  ? 697 HOH A O   1 
HETATM 7523 O O   . HOH F 4 .   ? -15.763   13.153    9.950     1.000 48.66993  ? 698 HOH A O   1 
HETATM 7524 O O   . HOH F 4 .   ? -64.36500 2.11600   -15.74800 1.000 65.61587  ? 699 HOH A O   1 
HETATM 7525 O O   . HOH F 4 .   ? -39.01200 12.56300  -7.37300  1.000 59.43814  ? 700 HOH A O   1 
HETATM 7526 O O   . HOH F 4 .   ? -13.37500 -2.78400  -13.33300 1.000 49.89589  ? 701 HOH A O   1 
HETATM 7527 O O   . HOH F 4 .   ? -26.69000 -4.96000  -13.02300 1.000 48.49402  ? 702 HOH A O   1 
HETATM 7528 O O   . HOH F 4 .   ? -1.29200  24.05900  -19.77900 1.000 51.55032  ? 703 HOH A O   1 
HETATM 7529 O O   . HOH F 4 .   ? -45.80500 0.50600   2.66200   1.000 39.09236  ? 704 HOH A O   1 
HETATM 7530 O O   . HOH F 4 .   ? -10.58500 -6.51200  0.27000   1.000 40.14809  ? 705 HOH A O   1 
HETATM 7531 O O   . HOH F 4 .   ? -77.33400 0.84500   -27.30700 1.000 57.83770  ? 706 HOH A O   1 
HETATM 7532 O O   . HOH F 4 .   ? -50.41500 -1.24300  7.78500   1.000 63.96251  ? 707 HOH A O   1 
HETATM 7533 O O   . HOH F 4 .   ? -48.88500 5.92200   9.06100   1.000 50.15210  ? 708 HOH A O   1 
HETATM 7534 O O   . HOH F 4 .   ? -43.600   18.903    -0.759    1.000 54.04249  ? 709 HOH A O   1 
HETATM 7535 O O   . HOH F 4 .   ? -19.52900 -2.46300  12.36800  1.000 51.60495  ? 710 HOH A O   1 
HETATM 7536 O O   . HOH F 4 .   ? -30.19200 -8.07500  -12.85900 1.000 46.61946  ? 711 HOH A O   1 
HETATM 7537 O O   . HOH F 4 .   ? -2.19700  -6.28900  -0.60700  1.000 45.14697  ? 712 HOH A O   1 
HETATM 7538 O O   . HOH F 4 .   ? -19.77600 -17.99600 3.03900   1.000 36.32317  ? 713 HOH A O   1 
HETATM 7539 O O   . HOH F 4 .   ? -9.76400  -8.80400  -1.06200  1.000 38.42940  ? 714 HOH A O   1 
HETATM 7540 O O   . HOH F 4 .   ? -74.157   -16.796   0.244     1.000 50.69384  ? 715 HOH A O   1 
HETATM 7541 O O   . HOH F 4 .   ? -23.85500 17.44900  4.09800   1.000 47.41057  ? 716 HOH A O   1 
HETATM 7542 O O   . HOH F 4 .   ? -34.53200 18.84400  8.14200   1.000 72.00519  ? 717 HOH A O   1 
HETATM 7543 O O   . HOH F 4 .   ? -48.63300 -0.82700  2.39600   1.000 52.43353  ? 718 HOH A O   1 
HETATM 7544 O O   . HOH F 4 .   ? -50.80000 -14.94600 -16.64100 1.000 45.56014  ? 719 HOH A O   1 
HETATM 7545 O O   . HOH F 4 .   ? -66.01600 0.31700   -26.67800 1.000 61.70635  ? 720 HOH A O   1 
HETATM 7546 O O   . HOH F 4 .   ? -10.01500 -5.63700  -7.33300  1.000 27.85495  ? 721 HOH A O   1 
HETATM 7547 O O   . HOH F 4 .   ? -10.85200 -7.55100  2.43200   1.000 41.83640  ? 722 HOH A O   1 
HETATM 7548 O O   . HOH F 4 .   ? -50.29700 -13.30000 -20.89200 1.000 56.21304  ? 723 HOH A O   1 
HETATM 7549 O O   . HOH F 4 .   ? -5.943    24.876    -0.470    1.000 46.83443  ? 724 HOH A O   1 
HETATM 7550 O O   . HOH F 4 .   ? -15.227   8.314     18.539    1.000 74.79223  ? 725 HOH A O   1 
HETATM 7551 O O   . HOH F 4 .   ? -81.64400 -17.26600 -18.70100 1.000 67.14471  ? 726 HOH A O   1 
HETATM 7552 O O   . HOH F 4 .   ? -35.22200 -11.36000 13.25500  1.000 55.12208  ? 727 HOH A O   1 
HETATM 7553 O O   . HOH F 4 .   ? -33.11900 -5.95400  15.15400  1.000 46.09944  ? 728 HOH A O   1 
HETATM 7554 O O   . HOH F 4 .   ? -61.86300 -11.89700 -29.00400 1.000 41.89195  ? 729 HOH A O   1 
HETATM 7555 O O   . HOH F 4 .   ? -46.74200 5.78600   8.25600   1.000 60.66718  ? 730 HOH A O   1 
HETATM 7556 O O   . HOH F 4 .   ? -57.54700 -7.23800  -9.43300  1.000 44.56059  ? 731 HOH A O   1 
HETATM 7557 O O   . HOH F 4 .   ? -22.64200 -14.99100 16.34300  1.000 59.92318  ? 732 HOH A O   1 
HETATM 7558 O O   . HOH F 4 .   ? -68.16200 -2.50400  -26.92300 1.000 65.58765  ? 733 HOH A O   1 
HETATM 7559 O O   . HOH F 4 .   ? -46.41600 4.31200   -3.42500  1.000 59.40758  ? 734 HOH A O   1 
HETATM 7560 O O   . HOH F 4 .   ? -36.53800 4.30300   20.91400  1.000 78.64415  ? 735 HOH A O   1 
HETATM 7561 O O   . HOH F 4 .   ? -3.12800  -11.26400 -6.61900  1.000 44.92451  ? 736 HOH A O   1 
HETATM 7562 O O   . HOH F 4 .   ? -53.63500 -1.79800  -1.43300  1.000 46.64382  ? 737 HOH A O   1 
HETATM 7563 O O   . HOH F 4 .   ? -42.601   18.677    -2.820    1.000 48.50457  ? 738 HOH A O   1 
HETATM 7564 O O   . HOH F 4 .   ? -41.31500 -14.45700 -10.98900 1.000 57.41887  ? 739 HOH A O   1 
HETATM 7565 O O   . HOH F 4 .   ? -22.09300 -5.18700  -17.19500 1.000 57.79435  ? 740 HOH A O   1 
HETATM 7566 O O   . HOH F 4 .   ? -5.13300  -11.00700 -8.08200  1.000 43.60524  ? 741 HOH A O   1 
HETATM 7567 O O   . HOH F 4 .   ? 6.12200   16.26000  -4.94300  1.000 52.42656  ? 742 HOH A O   1 
HETATM 7568 O O   . HOH F 4 .   ? -39.81400 0.23900   18.67500  1.000 69.81261  ? 743 HOH A O   1 
HETATM 7569 O O   . HOH F 4 .   ? -46.84400 3.37300   -5.75200  1.000 56.90537  ? 744 HOH A O   1 
HETATM 7570 O O   . HOH F 4 .   ? -45.45100 4.83600   -1.39000  1.000 62.66860  ? 745 HOH A O   1 
HETATM 7571 O O   . HOH F 4 .   ? -86.730   -10.670   -9.006    1.000 39.38605  ? 746 HOH A O   1 
HETATM 7572 O O   . HOH F 4 .   ? -24.66900 21.36100  -12.64300 1.000 53.54359  ? 747 HOH A O   1 
HETATM 7573 O O   . HOH F 4 .   ? -60.54900 -30.36900 -19.27500 1.000 57.19835  ? 748 HOH A O   1 
HETATM 7574 O O   . HOH F 4 .   ? -37.27400 10.63500  -7.06400  1.000 52.50069  ? 749 HOH A O   1 
HETATM 7575 O O   . HOH F 4 .   ? -57.62100 -31.53700 -21.60500 1.000 37.60016  ? 750 HOH A O   1 
HETATM 7576 O O   . HOH F 4 .   ? -26.99400 14.34300  7.04600   1.000 50.62685  ? 751 HOH A O   1 
HETATM 7577 O O   . HOH F 4 .   ? -26.69600 20.99200  -11.73800 1.000 61.57480  ? 752 HOH A O   1 
HETATM 7578 O O   . HOH F 4 .   ? -56.58400 -4.14700  -17.98000 1.000 55.94760  ? 753 HOH A O   1 
HETATM 7579 O O   . HOH F 4 .   ? -6.98000  0.97100   4.89500   1.000 59.11772  ? 754 HOH A O   1 
HETATM 7580 O O   . HOH F 4 .   ? 4.15700   15.62300  8.07600   1.000 64.12206  ? 755 HOH A O   1 
HETATM 7581 O O   . HOH F 4 .   ? -85.039   -8.489    -1.063    1.000 65.87397  ? 756 HOH A O   1 
HETATM 7582 O O   . HOH F 4 .   ? -33.53100 -8.33100  13.90800  1.000 44.11077  ? 757 HOH A O   1 
HETATM 7583 O O   . HOH F 4 .   ? -49.43400 -1.49200  5.10500   1.000 50.16730  ? 758 HOH A O   1 
HETATM 7584 O O   . HOH F 4 .   ? -60.32500 -17.72800 -5.36400  1.000 37.52883  ? 759 HOH A O   1 
HETATM 7585 O O   . HOH F 4 .   ? -46.68500 3.22400   2.25000   1.000 59.55247  ? 760 HOH A O   1 
HETATM 7586 O O   . HOH F 4 .   ? -74.93500 -22.40400 -35.08700 1.000 66.29402  ? 761 HOH A O   1 
HETATM 7587 O O   . HOH F 4 .   ? -40.06400 -20.45700 2.82700   1.000 56.64710  ? 762 HOH A O   1 
HETATM 7588 O O   . HOH F 4 .   ? -10.74900 -0.39500  6.99300   1.000 59.70978  ? 763 HOH A O   1 
HETATM 7589 O O   . HOH F 4 .   ? -58.66400 0.49200   -17.05000 1.000 45.76592  ? 764 HOH A O   1 
HETATM 7590 O O   . HOH F 4 .   ? 2.87600   9.89700   -18.49500 1.000 64.95663  ? 765 HOH A O   1 
HETATM 7591 O O   . HOH F 4 .   ? -56.19000 -1.51900  -9.95000  1.000 53.29718  ? 766 HOH A O   1 
HETATM 7592 O O   . HOH F 4 .   ? -56.65800 -0.80000  -15.81200 1.000 45.01668  ? 767 HOH A O   1 
HETATM 7593 O O   . HOH F 4 .   ? -49.40800 6.18600   6.58000   1.000 46.23945  ? 768 HOH A O   1 
HETATM 7594 O O   . HOH F 4 .   ? 3.96200   8.14700   -19.62800 1.000 60.14749  ? 769 HOH A O   1 
HETATM 7595 O O   . HOH F 4 .   ? -28.33300 15.55900  8.87500   1.000 52.43995  ? 770 HOH A O   1 
HETATM 7596 O O   . HOH F 4 .   ? -20.41700 -22.41000 12.77400  1.000 45.10470  ? 771 HOH A O   1 
HETATM 7597 O O   . HOH F 4 .   ? -19.59800 -21.51700 10.70500  1.000 58.27487  ? 772 HOH A O   1 
HETATM 7598 O O   . HOH F 4 .   ? -63.90900 1.44800   -28.34700 1.000 69.23271  ? 773 HOH A O   1 
HETATM 7599 O O   . HOH F 4 .   ? -16.24700 -24.09500 -5.31000  1.000 57.77948  ? 774 HOH A O   1 
HETATM 7600 O O   . HOH F 4 .   ? -22.39900 -23.92400 14.45200  1.000 62.69521  ? 775 HOH A O   1 
HETATM 7601 O O   . HOH F 4 .   ? -25.91200 17.44800  6.26300   1.000 59.69087  ? 776 HOH A O   1 
HETATM 7602 O O   . HOH F 4 .   ? -41.56500 1.41100   22.20000  1.000 59.99834  ? 777 HOH A O   1 
HETATM 7603 O O   . HOH F 4 .   ? -39.82100 2.53000   23.27600  1.000 56.79505  ? 778 HOH A O   1 
HETATM 7604 O O   . HOH F 4 .   ? -56.80400 -33.77800 -21.20000 1.000 45.67578  ? 779 HOH A O   1 
HETATM 7605 O O   . HOH F 4 .   ? -23.82200 16.95900  8.42300   1.000 68.56249  ? 780 HOH A O   1 
HETATM 7606 O O   . HOH F 4 .   ? -54.88300 0.71600   -13.34600 1.000 64.39503  ? 781 HOH A O   1 
HETATM 7607 O O   . HOH F 4 .   ? -27.96500 21.10300  9.08900   1.000 65.05099  ? 782 HOH A O   1 
HETATM 7608 O O   . HOH F 4 .   ? -54.99500 0.61500   -10.68800 1.000 42.00565  ? 783 HOH A O   1 
HETATM 7609 O O   . HOH F 4 .   ? -28.08200 19.66000  7.51400   1.000 55.46448  ? 784 HOH A O   1 
HETATM 7610 O O   . HOH G 4 .   ? -10.01000 -40.41500 -42.45900 1.000 51.37501  ? 601 HOH B O   1 
HETATM 7611 O O   . HOH G 4 .   ? -33.53800 -27.67300 -26.47600 1.000 53.38388  ? 602 HOH B O   1 
HETATM 7612 O O   . HOH G 4 .   ? -75.72000 -9.96400  -43.30900 1.000 90.27524  ? 603 HOH B O   1 
HETATM 7613 O O   . HOH G 4 .   ? 6.33900   -37.39100 -10.34900 1.000 42.08475  ? 604 HOH B O   1 
HETATM 7614 O O   . HOH G 4 .   ? -19.69800 -35.76500 -47.26300 1.000 35.93570  ? 605 HOH B O   1 
HETATM 7615 O O   . HOH G 4 .   ? -57.45200 -37.70000 -48.83800 1.000 66.87277  ? 606 HOH B O   1 
HETATM 7616 O O   . HOH G 4 .   ? -18.19200 -14.68600 -42.13000 1.000 44.12659  ? 607 HOH B O   1 
HETATM 7617 O O   . HOH G 4 .   ? -7.40700  -40.68800 0.64000   1.000 57.32202  ? 608 HOH B O   1 
HETATM 7618 O O   . HOH G 4 .   ? 5.44500   -40.43400 -7.49400  1.000 56.62976  ? 609 HOH B O   1 
HETATM 7619 O O   . HOH G 4 .   ? -11.48900 -49.89200 -8.76300  1.000 46.15523  ? 610 HOH B O   1 
HETATM 7620 O O   . HOH G 4 .   ? -3.897    -12.916   -19.800   1.000 79.73390  ? 611 HOH B O   1 
HETATM 7621 O O   . HOH G 4 .   ? -25.37100 -31.19200 -40.82100 1.000 39.06853  ? 612 HOH B O   1 
HETATM 7622 O O   . HOH G 4 .   ? -20.65800 -49.01200 -21.43700 1.000 30.48771  ? 613 HOH B O   1 
HETATM 7623 O O   . HOH G 4 .   ? -20.14900 -50.99300 -56.50100 1.000 45.80961  ? 614 HOH B O   1 
HETATM 7624 O O   . HOH G 4 .   ? -40.70100 -21.69000 -52.68700 1.000 49.23470  ? 615 HOH B O   1 
HETATM 7625 O O   . HOH G 4 .   ? -55.05900 -30.53800 -36.38200 1.000 54.17805  ? 616 HOH B O   1 
HETATM 7626 O O   . HOH G 4 .   ? -58.78300 -24.03300 -29.54200 1.000 58.25074  ? 617 HOH B O   1 
HETATM 7627 O O   . HOH G 4 .   ? -17.94600 -34.61700 -40.82200 1.000 34.19325  ? 618 HOH B O   1 
HETATM 7628 O O   . HOH G 4 .   ? 3.80300   -45.90800 -23.93200 1.000 41.35542  ? 619 HOH B O   1 
HETATM 7629 O O   . HOH G 4 .   ? -6.96800  -21.88600 -13.48900 1.000 51.05591  ? 620 HOH B O   1 
HETATM 7630 O O   . HOH G 4 .   ? -33.16700 -41.68200 -43.43300 1.000 59.34540  ? 621 HOH B O   1 
HETATM 7631 O O   . HOH G 4 .   ? -11.62300 -43.65100 -30.32100 1.000 23.86888  ? 622 HOH B O   1 
HETATM 7632 O O   . HOH G 4 .   ? -38.57800 -26.39100 -55.59300 1.000 52.67382  ? 623 HOH B O   1 
HETATM 7633 O O   . HOH G 4 .   ? -46.83600 -25.13200 -58.63400 1.000 42.03045  ? 624 HOH B O   1 
HETATM 7634 O O   . HOH G 4 .   ? -48.70500 -11.15300 -36.54300 1.000 50.21043  ? 625 HOH B O   1 
HETATM 7635 O O   . HOH G 4 .   ? -6.27800  -29.60200 -19.73200 1.000 35.37162  ? 626 HOH B O   1 
HETATM 7636 O O   . HOH G 4 .   ? -63.60400 -34.47100 -31.37400 1.000 73.35941  ? 627 HOH B O   1 
HETATM 7637 O O   . HOH G 4 .   ? -29.93900 -37.92400 -39.84400 1.000 49.52130  ? 628 HOH B O   1 
HETATM 7638 O O   . HOH G 4 .   ? 0.65900   -24.54500 -12.84000 1.000 56.43568  ? 629 HOH B O   1 
HETATM 7639 O O   . HOH G 4 .   ? -16.13300 -54.33100 -17.55800 1.000 37.23325  ? 630 HOH B O   1 
HETATM 7640 O O   . HOH G 4 .   ? -38.85200 -21.35400 -25.69000 1.000 66.01536  ? 631 HOH B O   1 
HETATM 7641 O O   . HOH G 4 .   ? -18.83200 -35.01200 -27.60600 1.000 31.82491  ? 632 HOH B O   1 
HETATM 7642 O O   . HOH G 4 .   ? -1.69600  -27.22800 -40.01000 1.000 46.30632  ? 633 HOH B O   1 
HETATM 7643 O O   . HOH G 4 .   ? -61.549   -12.772   -54.185   1.000 46.26464  ? 634 HOH B O   1 
HETATM 7644 O O   . HOH G 4 .   ? -16.60700 -42.68000 -21.26300 1.000 40.97785  ? 635 HOH B O   1 
HETATM 7645 O O   . HOH G 4 .   ? -13.63300 -51.05700 -10.78700 1.000 41.03315  ? 636 HOH B O   1 
HETATM 7646 O O   . HOH G 4 .   ? -46.098   -20.287   -59.427   1.000 47.22017  ? 637 HOH B O   1 
HETATM 7647 O O   . HOH G 4 .   ? -23.02700 -36.19000 -46.07100 1.000 40.04855  ? 638 HOH B O   1 
HETATM 7648 O O   . HOH G 4 .   ? -7.31000  -49.57900 -3.67200  1.000 47.17995  ? 639 HOH B O   1 
HETATM 7649 O O   . HOH G 4 .   ? -26.76200 -42.41000 -42.95400 1.000 49.34314  ? 640 HOH B O   1 
HETATM 7650 O O   . HOH G 4 .   ? -11.97100 -57.54800 -18.04800 1.000 36.78573  ? 641 HOH B O   1 
HETATM 7651 O O   . HOH G 4 .   ? -13.93200 -46.76400 -38.11800 1.000 45.20995  ? 642 HOH B O   1 
HETATM 7652 O O   . HOH G 4 .   ? -12.06000 -38.73900 -17.96300 1.000 28.69568  ? 643 HOH B O   1 
HETATM 7653 O O   . HOH G 4 .   ? -15.93200 -35.72300 -20.92100 1.000 44.37751  ? 644 HOH B O   1 
HETATM 7654 O O   . HOH G 4 .   ? -13.48300 -47.30600 -27.93100 1.000 25.72001  ? 645 HOH B O   1 
HETATM 7655 O O   . HOH G 4 .   ? -11.85500 -28.77500 -13.90100 1.000 51.60614  ? 646 HOH B O   1 
HETATM 7656 O O   . HOH G 4 .   ? -12.51400 -36.55400 0.47300   1.000 50.30206  ? 647 HOH B O   1 
HETATM 7657 O O   . HOH G 4 .   ? -33.22600 -11.46400 -35.09600 1.000 70.30840  ? 648 HOH B O   1 
HETATM 7658 O O   . HOH G 4 .   ? -17.66900 -8.52000  -34.73100 1.000 43.53656  ? 649 HOH B O   1 
HETATM 7659 O O   . HOH G 4 .   ? -36.43400 -10.02400 -23.82100 1.000 64.69562  ? 650 HOH B O   1 
HETATM 7660 O O   . HOH G 4 .   ? -33.20500 -48.10500 -49.39400 1.000 63.55474  ? 651 HOH B O   1 
HETATM 7661 O O   . HOH G 4 .   ? -9.22400  -50.92700 -28.96100 1.000 40.55162  ? 652 HOH B O   1 
HETATM 7662 O O   . HOH G 4 .   ? 0.99200   -34.32400 -24.10700 1.000 42.99852  ? 653 HOH B O   1 
HETATM 7663 O O   . HOH G 4 .   ? 0.73800   -38.82700 -35.74900 1.000 31.63243  ? 654 HOH B O   1 
HETATM 7664 O O   . HOH G 4 .   ? -59.46400 -27.96500 -56.32700 1.000 62.38510  ? 655 HOH B O   1 
HETATM 7665 O O   . HOH G 4 .   ? -53.48100 -27.11100 -60.31500 1.000 46.95345  ? 656 HOH B O   1 
HETATM 7666 O O   . HOH G 4 .   ? -26.82100 -33.05100 -39.07300 1.000 32.94709  ? 657 HOH B O   1 
HETATM 7667 O O   . HOH G 4 .   ? -9.84200  -51.62900 -25.47700 1.000 40.52198  ? 658 HOH B O   1 
HETATM 7668 O O   . HOH G 4 .   ? -38.59200 -26.73700 -48.28600 1.000 60.28209  ? 659 HOH B O   1 
HETATM 7669 O O   . HOH G 4 .   ? -19.74900 -8.27600  -34.24600 1.000 49.17806  ? 660 HOH B O   1 
HETATM 7670 O O   . HOH G 4 .   ? -33.02100 -25.09500 -58.16400 1.000 57.04423  ? 661 HOH B O   1 
HETATM 7671 O O   . HOH G 4 .   ? -20.04700 -47.32500 -19.36600 1.000 36.79601  ? 662 HOH B O   1 
HETATM 7672 O O   . HOH G 4 .   ? -22.97100 -7.12300  -18.46700 1.000 62.92009  ? 663 HOH B O   1 
HETATM 7673 O O   . HOH G 4 .   ? -25.738   -53.157   -44.501   1.000 59.32780  ? 664 HOH B O   1 
HETATM 7674 O O   . HOH G 4 .   ? -7.12300  -50.42000 -29.89200 1.000 34.01273  ? 665 HOH B O   1 
HETATM 7675 O O   . HOH G 4 .   ? -14.18800 -44.63800 -29.76600 1.000 26.98929  ? 666 HOH B O   1 
HETATM 7676 O O   . HOH G 4 .   ? -44.57100 -16.77800 -24.84200 1.000 32.08524  ? 667 HOH B O   1 
HETATM 7677 O O   . HOH G 4 .   ? -22.62100 -45.25100 -24.32100 1.000 45.43190  ? 668 HOH B O   1 
HETATM 7678 O O   . HOH G 4 .   ? -0.36300  -20.58500 -14.79800 1.000 57.43177  ? 669 HOH B O   1 
HETATM 7679 O O   . HOH G 4 .   ? -15.81400 -29.04500 -37.57800 1.000 38.69216  ? 670 HOH B O   1 
HETATM 7680 O O   . HOH G 4 .   ? -14.64200 -6.91800  -21.11600 1.000 62.47335  ? 671 HOH B O   1 
HETATM 7681 O O   . HOH G 4 .   ? -9.17100  -47.59000 -49.93700 1.000 54.07793  ? 672 HOH B O   1 
HETATM 7682 O O   . HOH G 4 .   ? -46.22500 -17.70800 -48.18000 1.000 35.15507  ? 673 HOH B O   1 
HETATM 7683 O O   . HOH G 4 .   ? -30.06400 -33.71600 -45.58300 1.000 44.10313  ? 674 HOH B O   1 
HETATM 7684 O O   . HOH G 4 .   ? -13.48200 -36.67100 -28.28900 1.000 39.32430  ? 675 HOH B O   1 
HETATM 7685 O O   . HOH G 4 .   ? -31.54300 -23.96500 -39.96200 1.000 44.82063  ? 676 HOH B O   1 
HETATM 7686 O O   . HOH G 4 .   ? -28.64700 -20.27400 -48.43700 1.000 45.44866  ? 677 HOH B O   1 
HETATM 7687 O O   . HOH G 4 .   ? -2.40900  -23.73200 -21.82100 1.000 39.30493  ? 678 HOH B O   1 
HETATM 7688 O O   . HOH G 4 .   ? -14.05500 -37.26800 -2.20400  1.000 56.42990  ? 679 HOH B O   1 
HETATM 7689 O O   . HOH G 4 .   ? -16.29100 -38.91600 -26.21200 1.000 28.45604  ? 680 HOH B O   1 
HETATM 7690 O O   . HOH G 4 .   ? -54.85700 -38.02700 -37.07000 1.000 64.54354  ? 681 HOH B O   1 
HETATM 7691 O O   . HOH G 4 .   ? -11.55200 -22.80600 -14.99900 1.000 44.64045  ? 682 HOH B O   1 
HETATM 7692 O O   . HOH G 4 .   ? -13.45700 -13.23600 -45.85600 1.000 53.17512  ? 683 HOH B O   1 
HETATM 7693 O O   . HOH G 4 .   ? -3.94000  -37.67600 -32.11500 1.000 41.20492  ? 684 HOH B O   1 
HETATM 7694 O O   . HOH G 4 .   ? -57.87300 -4.60800  -30.41600 1.000 55.81277  ? 685 HOH B O   1 
HETATM 7695 O O   . HOH G 4 .   ? -6.28800  -37.01000 -34.23200 1.000 38.37866  ? 686 HOH B O   1 
HETATM 7696 O O   . HOH G 4 .   ? -48.83400 -18.41600 -25.35600 1.000 54.84355  ? 687 HOH B O   1 
HETATM 7697 O O   . HOH G 4 .   ? -18.87400 -30.73700 -19.33400 1.000 57.52962  ? 688 HOH B O   1 
HETATM 7698 O O   . HOH G 4 .   ? -15.19000 -35.57800 -25.62400 1.000 42.97526  ? 689 HOH B O   1 
HETATM 7699 O O   . HOH G 4 .   ? -13.01600 -34.35600 -26.94900 1.000 29.84238  ? 690 HOH B O   1 
HETATM 7700 O O   . HOH G 4 .   ? -16.18700 -27.85200 -34.98000 1.000 31.21118  ? 691 HOH B O   1 
HETATM 7701 O O   . HOH G 4 .   ? -19.52900 -42.86200 -40.43100 1.000 40.55213  ? 692 HOH B O   1 
HETATM 7702 O O   . HOH G 4 .   ? -28.17400 -49.08100 -45.61000 1.000 67.20280  ? 693 HOH B O   1 
HETATM 7703 O O   . HOH G 4 .   ? -6.58400  -11.43400 -18.24400 1.000 64.15129  ? 694 HOH B O   1 
HETATM 7704 O O   . HOH G 4 .   ? -5.42100  -35.06700 -32.52600 1.000 31.16005  ? 695 HOH B O   1 
HETATM 7705 O O   . HOH G 4 .   ? 2.79700   -49.11600 -2.84500  1.000 61.01025  ? 696 HOH B O   1 
HETATM 7706 O O   . HOH G 4 .   ? -24.20900 -28.45800 -20.73400 1.000 64.45467  ? 697 HOH B O   1 
HETATM 7707 O O   . HOH G 4 .   ? -16.45100 -36.88100 -27.67800 1.000 35.39544  ? 698 HOH B O   1 
HETATM 7708 O O   . HOH G 4 .   ? -13.34700 -29.01800 -12.06700 1.000 63.03170  ? 699 HOH B O   1 
HETATM 7709 O O   . HOH G 4 .   ? -3.24100  -34.84000 -30.94400 1.000 34.70323  ? 700 HOH B O   1 
HETATM 7710 O O   . HOH G 4 .   ? -26.33800 -25.34400 -24.41800 1.000 38.07265  ? 701 HOH B O   1 
HETATM 7711 O O   . HOH G 4 .   ? -34.02700 -19.79800 -42.28800 1.000 62.92786  ? 702 HOH B O   1 
HETATM 7712 O O   . HOH G 4 .   ? -30.82300 -20.99400 -58.66600 1.000 58.75558  ? 703 HOH B O   1 
HETATM 7713 O O   . HOH G 4 .   ? -72.96900 -16.79500 -33.93300 1.000 52.84066  ? 704 HOH B O   1 
HETATM 7714 O O   . HOH G 4 .   ? -4.38900  -37.95000 -45.60700 1.000 57.49477  ? 705 HOH B O   1 
HETATM 7715 O O   . HOH G 4 .   ? -23.69200 -26.91700 -23.63300 1.000 43.59606  ? 706 HOH B O   1 
HETATM 7716 O O   . HOH G 4 .   ? -15.93400 -21.08000 -48.93300 1.000 48.52910  ? 707 HOH B O   1 
HETATM 7717 O O   . HOH G 4 .   ? -51.71000 -10.68100 -44.39500 1.000 44.25790  ? 708 HOH B O   1 
HETATM 7718 O O   . HOH G 4 .   ? -10.10900 -54.20300 -30.69700 1.000 42.68003  ? 709 HOH B O   1 
HETATM 7719 O O   . HOH G 4 .   ? -65.47300 -14.81200 -35.43600 1.000 72.61859  ? 710 HOH B O   1 
HETATM 7720 O O   . HOH G 4 .   ? -11.37300 -26.58900 -15.12500 1.000 37.29520  ? 711 HOH B O   1 
HETATM 7721 O O   . HOH G 4 .   ? -15.74800 -33.92300 -23.90300 1.000 35.46857  ? 712 HOH B O   1 
HETATM 7722 O O   . HOH G 4 .   ? -58.91000 -11.59000 -28.15300 1.000 40.51645  ? 713 HOH B O   1 
HETATM 7723 O O   . HOH G 4 .   ? -69.26200 0.60000   -40.31300 1.000 68.09095  ? 714 HOH B O   1 
HETATM 7724 O O   . HOH G 4 .   ? -66.19300 -27.07800 -34.79700 1.000 66.49190  ? 715 HOH B O   1 
HETATM 7725 O O   . HOH G 4 .   ? -5.06200  -20.94700 -14.98700 1.000 54.12723  ? 716 HOH B O   1 
HETATM 7726 O O   . HOH G 4 .   ? -18.33200 -54.57200 -17.55900 1.000 38.13651  ? 717 HOH B O   1 
HETATM 7727 O O   . HOH G 4 .   ? -29.47100 -37.81600 -52.81400 1.000 55.48070  ? 718 HOH B O   1 
HETATM 7728 O O   . HOH G 4 .   ? -20.72400 -52.29000 -19.06900 1.000 41.73634  ? 719 HOH B O   1 
HETATM 7729 O O   . HOH G 4 .   ? -34.27800 -28.85400 -50.08400 1.000 50.86452  ? 720 HOH B O   1 
HETATM 7730 O O   . HOH G 4 .   ? 6.40700   -53.68400 -23.63600 1.000 59.89416  ? 721 HOH B O   1 
HETATM 7731 O O   . HOH G 4 .   ? -14.14900 -20.08000 -51.59200 1.000 67.37922  ? 722 HOH B O   1 
HETATM 7732 O O   . HOH G 4 .   ? -19.01400 -36.02700 -20.50700 1.000 35.32771  ? 723 HOH B O   1 
HETATM 7733 O O   . HOH G 4 .   ? -2.66600  -26.42700 -23.15900 1.000 34.34104  ? 724 HOH B O   1 
HETATM 7734 O O   . HOH G 4 .   ? -5.21300  -19.62000 -27.44700 1.000 47.51440  ? 725 HOH B O   1 
HETATM 7735 O O   . HOH G 4 .   ? -8.26000  -14.65100 -32.07300 1.000 42.54537  ? 726 HOH B O   1 
HETATM 7736 O O   . HOH G 4 .   ? -7.89600  -58.79600 -6.78000  1.000 53.78882  ? 727 HOH B O   1 
HETATM 7737 O O   . HOH G 4 .   ? -21.87200 -24.87400 -58.81900 1.000 53.75739  ? 728 HOH B O   1 
HETATM 7738 O O   . HOH G 4 .   ? -46.39600 -26.05900 -42.32300 1.000 56.82138  ? 729 HOH B O   1 
HETATM 7739 O O   . HOH G 4 .   ? -2.63500  -22.97000 -11.17700 1.000 51.35562  ? 730 HOH B O   1 
HETATM 7740 O O   . HOH G 4 .   ? -7.71300  -57.32000 -2.15000  1.000 44.98626  ? 731 HOH B O   1 
HETATM 7741 O O   . HOH G 4 .   ? -18.49500 -48.92300 -11.22800 1.000 47.21461  ? 732 HOH B O   1 
HETATM 7742 O O   . HOH G 4 .   ? -14.44100 -55.18300 -9.87400  1.000 43.09069  ? 733 HOH B O   1 
HETATM 7743 O O   . HOH G 4 .   ? -51.85500 -5.73300  -39.33100 1.000 58.68544  ? 734 HOH B O   1 
HETATM 7744 O O   . HOH G 4 .   ? -56.55400 0.48500   -36.17300 1.000 76.21920  ? 735 HOH B O   1 
HETATM 7745 O O   . HOH G 4 .   ? -13.54200 -39.47200 -2.33400  1.000 54.70959  ? 736 HOH B O   1 
HETATM 7746 O O   . HOH G 4 .   ? -15.15900 -53.52200 -8.63200  1.000 45.45080  ? 737 HOH B O   1 
HETATM 7747 O O   . HOH G 4 .   ? 1.87000   -38.04700 -24.30000 1.000 50.26722  ? 738 HOH B O   1 
HETATM 7748 O O   . HOH G 4 .   ? -13.03600 -24.03700 -47.47300 1.000 52.73528  ? 739 HOH B O   1 
HETATM 7749 O O   . HOH G 4 .   ? -74.57500 -20.01800 -34.73900 1.000 69.01366  ? 740 HOH B O   1 
HETATM 7750 O O   . HOH G 4 .   ? -47.41900 -12.39800 -43.19400 1.000 51.65462  ? 741 HOH B O   1 
HETATM 7751 O O   . HOH G 4 .   ? -14.36800 -50.87700 -6.97400  1.000 42.48683  ? 742 HOH B O   1 
HETATM 7752 O O   . HOH G 4 .   ? -35.05000 -48.89700 -47.73900 1.000 48.08046  ? 743 HOH B O   1 
HETATM 7753 O O   . HOH G 4 .   ? -29.500   -1.960    -31.299   1.000 72.45673  ? 744 HOH B O   1 
HETATM 7754 O O   . HOH G 4 .   ? -4.85400  -22.40300 -12.34100 1.000 43.05024  ? 745 HOH B O   1 
HETATM 7755 O O   . HOH G 4 .   ? -73.13700 -18.11600 -36.43200 1.000 65.63123  ? 746 HOH B O   1 
HETATM 7756 O O   . HOH G 4 .   ? -53.85900 -8.73000  -45.49500 1.000 46.09049  ? 747 HOH B O   1 
HETATM 7757 O O   . HOH G 4 .   ? -24.04800 -22.59100 -58.74700 1.000 56.35792  ? 748 HOH B O   1 
HETATM 7758 O O   . HOH G 4 .   ? -11.913   -60.290   -16.829   1.000 43.88025  ? 749 HOH B O   1 
HETATM 7759 O O   . HOH G 4 .   ? -2.86400  -21.46600 -13.94700 1.000 42.60100  ? 750 HOH B O   1 
HETATM 7760 O O   . HOH G 4 .   ? -15.35400 -23.68600 -48.99000 1.000 52.54791  ? 751 HOH B O   1 
HETATM 7761 O O   . HOH G 4 .   ? -11.17200 -47.28000 -35.97800 1.000 41.25163  ? 752 HOH B O   1 
HETATM 7762 O O   . HOH G 4 .   ? -7.25200  -9.31900  -20.13400 1.000 54.05023  ? 753 HOH B O   1 
HETATM 7763 O O   . HOH G 4 .   ? -70.90200 0.76900   -38.79100 1.000 68.69121  ? 754 HOH B O   1 
HETATM 7764 O O   . HOH G 4 .   ? -23.32000 -5.10200  -19.77100 1.000 71.02582  ? 755 HOH B O   1 
HETATM 7765 O O   . HOH G 4 .   ? 8.36400   -37.99500 -23.72500 1.000 75.01875  ? 756 HOH B O   1 
HETATM 7766 O O   . HOH G 4 .   ? -34.91500 -24.58900 -59.98500 1.000 64.44221  ? 757 HOH B O   1 
HETATM 7767 O O   . HOH G 4 .   ? -28.70000 -39.23000 -51.34500 1.000 48.46639  ? 758 HOH B O   1 
HETATM 7768 O O   . HOH G 4 .   ? -34.17400 -48.09700 -42.20500 1.000 69.04642  ? 759 HOH B O   1 
HETATM 7769 O O   . HOH G 4 .   ? -9.27400  -29.55600 -3.50500  1.000 62.96559  ? 760 HOH B O   1 
HETATM 7770 O O   . HOH G 4 .   ? 3.19500   -38.94000 -26.41000 1.000 44.53417  ? 761 HOH B O   1 
HETATM 7771 O O   . HOH G 4 .   ? -56.987   -15.905   -61.585   1.000 62.02492  ? 762 HOH B O   1 
HETATM 7772 O O   . HOH G 4 .   ? 1.26800   -33.67300 -26.81400 1.000 47.93461  ? 763 HOH B O   1 
HETATM 7773 O O   . HOH G 4 .   ? -19.45400 -15.90600 -47.49400 1.000 58.11511  ? 764 HOH B O   1 
HETATM 7774 O O   . HOH G 4 .   ? -75.00900 -14.50600 -53.39200 1.000 64.71398  ? 765 HOH B O   1 
HETATM 7775 O O   . HOH G 4 .   ? -6.70600  -14.68200 -29.41700 1.000 56.31972  ? 766 HOH B O   1 
HETATM 7776 O O   . HOH G 4 .   ? -73.27100 -20.52100 -36.78200 1.000 61.94896  ? 767 HOH B O   1 
HETATM 7777 O O   . HOH G 4 .   ? -48.35000 -11.03200 -45.83200 1.000 49.87582  ? 768 HOH B O   1 
HETATM 7778 O O   . HOH G 4 .   ? -53.21800 -3.96400  -39.13300 1.000 69.96557  ? 769 HOH B O   1 
HETATM 7779 O O   . HOH G 4 .   ? -21.47800 -13.73800 -46.85700 1.000 56.48599  ? 770 HOH B O   1 
HETATM 7780 O O   . HOH G 4 .   ? -30.597   -1.260    -28.643   1.000 55.81048  ? 771 HOH B O   1 
HETATM 7781 O O   . HOH G 4 .   ? -36.43800 -28.13900 -47.94100 1.000 47.33521  ? 772 HOH B O   1 
HETATM 7782 O O   . HOH G 4 .   ? -12.465   -50.584   -35.018   1.000 54.08265  ? 773 HOH B O   1 
HETATM 7783 O O   . HOH G 4 .   ? -30.465   -0.078    -30.862   1.000 54.85455  ? 774 HOH B O   1 
HETATM 7784 O O   . HOH G 4 .   ? -45.94100 -14.71400 -48.04700 1.000 42.65416  ? 775 HOH B O   1 
HETATM 7785 O O   . HOH G 4 .   ? -35.67300 -17.38700 -40.55400 1.000 60.21142  ? 776 HOH B O   1 
HETATM 7786 O O   . HOH G 4 .   ? -14.99900 -25.88800 -4.67600  1.000 65.27153  ? 777 HOH B O   1 
HETATM 7787 O O   . HOH G 4 .   ? -49.67400 -10.07200 -42.51000 1.000 55.32939  ? 778 HOH B O   1 
HETATM 7788 O O   . HOH G 4 .   ? 8.12500   -39.69400 -25.28400 1.000 47.14790  ? 779 HOH B O   1 
HETATM 7789 O O   . HOH G 4 .   ? -26.46300 -29.72800 -19.87700 1.000 70.86892  ? 780 HOH B O   1 
HETATM 7790 O O   . HOH G 4 .   ? -33.90300 -46.48700 -51.75600 1.000 62.67954  ? 781 HOH B O   1 
HETATM 7791 O O   . HOH G 4 .   ? -29.46100 -41.08400 -53.48800 1.000 56.86140  ? 782 HOH B O   1 
HETATM 7792 O O   . HOH G 4 .   ? -22.58900 -25.67800 -61.29100 1.000 63.28582  ? 783 HOH B O   1 
HETATM 7793 O O   . HOH G 4 .   ? -34.62500 -42.59100 -40.11600 1.000 59.91371  ? 784 HOH B O   1 
HETATM 7794 O O   . HOH G 4 .   ? -4.72900  -16.56200 -27.81500 1.000 70.76221  ? 785 HOH B O   1 
HETATM 7795 O O   . HOH G 4 .   ? -77.05800 -21.74800 -40.72000 1.000 65.40585  ? 786 HOH B O   1 
HETATM 7796 O O   . HOH G 4 .   ? -75.15300 -12.97600 -51.55400 1.000 51.08305  ? 787 HOH B O   1 
HETATM 7797 O O   . HOH G 4 .   ? -49.20300 -8.77300  -44.25300 1.000 52.97088  ? 788 HOH B O   1 
HETATM 7798 O O   . HOH G 4 .   ? -36.35800 -40.21700 -37.53500 1.000 52.81645  ? 789 HOH B O   1 
HETATM 7799 O O   . HOH G 4 .   ? -77.41700 -23.71900 -38.90700 1.000 77.17937  ? 790 HOH B O   1 
HETATM 7800 O O   . HOH G 4 .   ? -31.80900 -39.15700 -50.93200 1.000 49.34790  ? 791 HOH B O   1 
HETATM 7801 O O   . HOH G 4 .   ? -37.51100 -33.55900 -30.00700 1.000 62.11648  ? 792 HOH B O   1 
HETATM 7802 O O   . HOH G 4 .   ? -53.58200 -41.86600 -44.65000 1.000 65.52274  ? 793 HOH B O   1 
HETATM 7803 O O   . HOH G 4 .   ? -46.42200 -9.10900  -44.97700 1.000 57.63986  ? 794 HOH B O   1 
HETATM 7804 O O   . HOH G 4 .   ? -44.29000 -12.84700 -47.79600 1.000 53.30633  ? 795 HOH B O   1 
HETATM 7805 O O   . HOH G 4 .   ? -54.55400 -43.02800 -41.48800 1.000 52.52764  ? 796 HOH B O   1 
HETATM 7806 O O   . HOH G 4 .   ? -39.82200 -35.06600 -30.80700 1.000 50.07255  ? 797 HOH B O   1 
# 
