data_9CRA
# 
_entry.id   9CRA 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CRA         pdb_00009cra 10.2210/pdb9cra/pdb 
WWPDB D_1000286115 ?            ?                   
EMDB  EMD-45856    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-08 
2 'Structure model' 1 1 2025-02-05 
3 'Structure model' 1 2 2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.journal_volume'          
6  2 'Structure model' '_citation.page_first'              
7  2 'Structure model' '_citation.page_last'               
8  2 'Structure model' '_citation.pdbx_database_id_DOI'    
9  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
10 2 'Structure model' '_citation.title'                   
11 2 'Structure model' '_citation.year'                    
12 2 'Structure model' '_em_admin.last_update'             
13 3 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CRA 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'CryoEM Structure of the C-terminally truncated form of human NAD Kinase'              EMD-45832 'other EM volume'      
EMDB 'CryoEM Structure of the human full length NAD Kinase'                                 EMD-45831 'other EM volume'      
EMDB 'CryoEM Structure of the C-terminally truncated form of human NAD Kinase bound to NAD' EMD-45856 'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 gerta.hoxhaj@utsouthwestern.edu Gerta  Hoxhaj  ? 'principal investigator/group leader' 0000-0001-6179-3583 
4 gilles.labesse@cbs.cnrs.fr      Gilles Labesse ? 'principal investigator/group leader' 0000-0002-6861-3300 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, Y.'      1 0000-0001-9601-4885 
'Chen, Z.'    2 0000-0002-1668-4051 
'Mary, C.'    3 0000-0003-3056-8839 
'Labesse, G.' 4 0000-0002-6861-3300 
'Hoxhaj, G.'  5 0000-0001-6179-3583 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Sci Adv' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2375-2548 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            11 
_citation.language                  ? 
_citation.page_first                eads2664 
_citation.page_last                 eads2664 
_citation.title                     'Cryo-EM structure and regulation of human NAD kinase.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/sciadv.ads2664 
_citation.pdbx_database_id_PubMed   39854463 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Praharaj, P.P.'  1  0000-0003-0425-5118 
primary 'Li, Y.'          2  0000-0001-9601-4885 
primary 'Mary, C.'        3  ?                   
primary 'Soflaee, M.H.'   4  0000-0003-4598-3955 
primary 'Ryu, K.'         5  0009-0005-8836-2720 
primary 'Kim, D.'         6  0000-0002-6060-0601 
primary 'Tran, D.H.'      7  0000-0003-3612-1464 
primary 'Dey, T.'         8  0000-0002-5504-2481 
primary 'Tom, H.J.'       9  0000-0001-9402-2371 
primary 'Rion, H.'        10 0000-0002-7827-6352 
primary 'Gelin, M.'       11 0000-0003-1320-8663 
primary 'Lemoff, A.'      12 ?                   
primary 'Zacharias, L.G.' 13 ?                   
primary 'Patricio, J.S.'  14 0000-0001-7045-4532 
primary 'Mathews, T.P.'   15 0000-0002-9355-8243 
primary 'Chen, Z.'        16 0000-0002-1668-4051 
primary 'Lionne, C.'      17 0000-0002-6348-5311 
primary 'Hoxhaj, G.'      18 0000-0001-6179-3583 
primary 'Labesse, G.'     19 0000-0002-6861-3300 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'NAD kinase'                      41069.910 4 2.7.1.23 ? 'C-terminal residues 91-437' ? 
2 non-polymer syn NICOTINAMIDE-ADENINE-DINUCLEOTIDE 663.425   4 ?        ? ?                            ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Poly(P)/ATP NAD kinase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPSPVTTFGPKATVETQDPASVRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESF
GAVKKKFTTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAV
VLRSRLKVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD
GVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGD
SISITTSTYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFELGLEHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPSPVTTFGPKATVETQDPASVRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESF
GAVKKKFTTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAV
VLRSRLKVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD
GVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGD
SISITTSTYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFELGLEHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        NICOTINAMIDE-ADENINE-DINUCLEOTIDE 
_pdbx_entity_nonpoly.comp_id     NAD 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   SER n 
1 4   PRO n 
1 5   VAL n 
1 6   THR n 
1 7   THR n 
1 8   PHE n 
1 9   GLY n 
1 10  PRO n 
1 11  LYS n 
1 12  ALA n 
1 13  THR n 
1 14  VAL n 
1 15  GLU n 
1 16  THR n 
1 17  GLN n 
1 18  ASP n 
1 19  PRO n 
1 20  ALA n 
1 21  SER n 
1 22  VAL n 
1 23  ARG n 
1 24  LEU n 
1 25  THR n 
1 26  TRP n 
1 27  ASN n 
1 28  LYS n 
1 29  SER n 
1 30  PRO n 
1 31  LYS n 
1 32  SER n 
1 33  VAL n 
1 34  LEU n 
1 35  VAL n 
1 36  ILE n 
1 37  LYS n 
1 38  LYS n 
1 39  MET n 
1 40  ARG n 
1 41  ASP n 
1 42  ALA n 
1 43  SER n 
1 44  LEU n 
1 45  LEU n 
1 46  GLN n 
1 47  PRO n 
1 48  PHE n 
1 49  LYS n 
1 50  GLU n 
1 51  LEU n 
1 52  CYS n 
1 53  THR n 
1 54  HIS n 
1 55  LEU n 
1 56  MET n 
1 57  GLU n 
1 58  GLU n 
1 59  ASN n 
1 60  MET n 
1 61  ILE n 
1 62  VAL n 
1 63  TYR n 
1 64  VAL n 
1 65  GLU n 
1 66  LYS n 
1 67  LYS n 
1 68  VAL n 
1 69  LEU n 
1 70  GLU n 
1 71  ASP n 
1 72  PRO n 
1 73  ALA n 
1 74  ILE n 
1 75  ALA n 
1 76  SER n 
1 77  ASP n 
1 78  GLU n 
1 79  SER n 
1 80  PHE n 
1 81  GLY n 
1 82  ALA n 
1 83  VAL n 
1 84  LYS n 
1 85  LYS n 
1 86  LYS n 
1 87  PHE n 
1 88  THR n 
1 89  THR n 
1 90  PHE n 
1 91  ARG n 
1 92  GLU n 
1 93  ASP n 
1 94  TYR n 
1 95  ASP n 
1 96  ASP n 
1 97  ILE n 
1 98  SER n 
1 99  ASN n 
1 100 GLN n 
1 101 ILE n 
1 102 ASP n 
1 103 PHE n 
1 104 ILE n 
1 105 ILE n 
1 106 CYS n 
1 107 LEU n 
1 108 GLY n 
1 109 GLY n 
1 110 ASP n 
1 111 GLY n 
1 112 THR n 
1 113 LEU n 
1 114 LEU n 
1 115 TYR n 
1 116 ALA n 
1 117 SER n 
1 118 SER n 
1 119 LEU n 
1 120 PHE n 
1 121 GLN n 
1 122 GLY n 
1 123 SER n 
1 124 VAL n 
1 125 PRO n 
1 126 PRO n 
1 127 VAL n 
1 128 MET n 
1 129 ALA n 
1 130 PHE n 
1 131 HIS n 
1 132 LEU n 
1 133 GLY n 
1 134 SER n 
1 135 LEU n 
1 136 GLY n 
1 137 PHE n 
1 138 LEU n 
1 139 THR n 
1 140 PRO n 
1 141 PHE n 
1 142 SER n 
1 143 PHE n 
1 144 GLU n 
1 145 ASN n 
1 146 PHE n 
1 147 GLN n 
1 148 SER n 
1 149 GLN n 
1 150 VAL n 
1 151 THR n 
1 152 GLN n 
1 153 VAL n 
1 154 ILE n 
1 155 GLU n 
1 156 GLY n 
1 157 ASN n 
1 158 ALA n 
1 159 ALA n 
1 160 VAL n 
1 161 VAL n 
1 162 LEU n 
1 163 ARG n 
1 164 SER n 
1 165 ARG n 
1 166 LEU n 
1 167 LYS n 
1 168 VAL n 
1 169 ARG n 
1 170 VAL n 
1 171 VAL n 
1 172 LYS n 
1 173 GLU n 
1 174 LEU n 
1 175 ARG n 
1 176 GLY n 
1 177 LYS n 
1 178 LYS n 
1 179 THR n 
1 180 ALA n 
1 181 VAL n 
1 182 HIS n 
1 183 ASN n 
1 184 GLY n 
1 185 LEU n 
1 186 GLY n 
1 187 GLU n 
1 188 ASN n 
1 189 GLY n 
1 190 SER n 
1 191 GLN n 
1 192 ALA n 
1 193 ALA n 
1 194 GLY n 
1 195 LEU n 
1 196 ASP n 
1 197 MET n 
1 198 ASP n 
1 199 VAL n 
1 200 GLY n 
1 201 LYS n 
1 202 GLN n 
1 203 ALA n 
1 204 MET n 
1 205 GLN n 
1 206 TYR n 
1 207 GLN n 
1 208 VAL n 
1 209 LEU n 
1 210 ASN n 
1 211 GLU n 
1 212 VAL n 
1 213 VAL n 
1 214 ILE n 
1 215 ASP n 
1 216 ARG n 
1 217 GLY n 
1 218 PRO n 
1 219 SER n 
1 220 SER n 
1 221 TYR n 
1 222 LEU n 
1 223 SER n 
1 224 ASN n 
1 225 VAL n 
1 226 ASP n 
1 227 VAL n 
1 228 TYR n 
1 229 LEU n 
1 230 ASP n 
1 231 GLY n 
1 232 HIS n 
1 233 LEU n 
1 234 ILE n 
1 235 THR n 
1 236 THR n 
1 237 VAL n 
1 238 GLN n 
1 239 GLY n 
1 240 ASP n 
1 241 GLY n 
1 242 VAL n 
1 243 ILE n 
1 244 VAL n 
1 245 SER n 
1 246 THR n 
1 247 PRO n 
1 248 THR n 
1 249 GLY n 
1 250 SER n 
1 251 THR n 
1 252 ALA n 
1 253 TYR n 
1 254 ALA n 
1 255 ALA n 
1 256 ALA n 
1 257 ALA n 
1 258 GLY n 
1 259 ALA n 
1 260 SER n 
1 261 MET n 
1 262 ILE n 
1 263 HIS n 
1 264 PRO n 
1 265 ASN n 
1 266 VAL n 
1 267 PRO n 
1 268 ALA n 
1 269 ILE n 
1 270 MET n 
1 271 ILE n 
1 272 THR n 
1 273 PRO n 
1 274 ILE n 
1 275 CYS n 
1 276 PRO n 
1 277 HIS n 
1 278 SER n 
1 279 LEU n 
1 280 SER n 
1 281 PHE n 
1 282 ARG n 
1 283 PRO n 
1 284 ILE n 
1 285 VAL n 
1 286 VAL n 
1 287 PRO n 
1 288 ALA n 
1 289 GLY n 
1 290 VAL n 
1 291 GLU n 
1 292 LEU n 
1 293 LYS n 
1 294 ILE n 
1 295 MET n 
1 296 LEU n 
1 297 SER n 
1 298 PRO n 
1 299 GLU n 
1 300 ALA n 
1 301 ARG n 
1 302 ASN n 
1 303 THR n 
1 304 ALA n 
1 305 TRP n 
1 306 VAL n 
1 307 SER n 
1 308 PHE n 
1 309 ASP n 
1 310 GLY n 
1 311 ARG n 
1 312 LYS n 
1 313 ARG n 
1 314 GLN n 
1 315 GLU n 
1 316 ILE n 
1 317 ARG n 
1 318 HIS n 
1 319 GLY n 
1 320 ASP n 
1 321 SER n 
1 322 ILE n 
1 323 SER n 
1 324 ILE n 
1 325 THR n 
1 326 THR n 
1 327 SER n 
1 328 THR n 
1 329 TYR n 
1 330 PRO n 
1 331 LEU n 
1 332 PRO n 
1 333 SER n 
1 334 ILE n 
1 335 CYS n 
1 336 VAL n 
1 337 ARG n 
1 338 ASP n 
1 339 PRO n 
1 340 VAL n 
1 341 SER n 
1 342 ASP n 
1 343 TRP n 
1 344 PHE n 
1 345 GLU n 
1 346 SER n 
1 347 LEU n 
1 348 ALA n 
1 349 GLN n 
1 350 CYS n 
1 351 LEU n 
1 352 HIS n 
1 353 TRP n 
1 354 ASN n 
1 355 VAL n 
1 356 ARG n 
1 357 LYS n 
1 358 LYS n 
1 359 GLN n 
1 360 ALA n 
1 361 HIS n 
1 362 PHE n 
1 363 GLU n 
1 364 LEU n 
1 365 GLY n 
1 366 LEU n 
1 367 GLU n 
1 368 HIS n 
1 369 HIS n 
1 370 HIS n 
1 371 HIS n 
1 372 HIS n 
1 373 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   373 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 NADK 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                          ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                          ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                           ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                         ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                        ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                           ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                            ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                        ? 'C5 H11 N O2 S'     149.211 
NAD non-polymer         . NICOTINAMIDE-ADENINE-DINUCLEOTIDE ? 'C21 H27 N7 O14 P2' 663.425 
PHE 'L-peptide linking' y PHENYLALANINE                     ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                           ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                            ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                         ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                          ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                            ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   67  ?   ?   ?   A . n 
A 1 2   PRO 2   68  ?   ?   ?   A . n 
A 1 3   SER 3   69  ?   ?   ?   A . n 
A 1 4   PRO 4   70  ?   ?   ?   A . n 
A 1 5   VAL 5   71  ?   ?   ?   A . n 
A 1 6   THR 6   72  ?   ?   ?   A . n 
A 1 7   THR 7   73  73  THR THR A . n 
A 1 8   PHE 8   74  74  PHE PHE A . n 
A 1 9   GLY 9   75  75  GLY GLY A . n 
A 1 10  PRO 10  76  76  PRO PRO A . n 
A 1 11  LYS 11  77  77  LYS LYS A . n 
A 1 12  ALA 12  78  78  ALA ALA A . n 
A 1 13  THR 13  79  79  THR THR A . n 
A 1 14  VAL 14  80  80  VAL VAL A . n 
A 1 15  GLU 15  89  ?   ?   ?   A . n 
A 1 16  THR 16  90  ?   ?   ?   A . n 
A 1 17  GLN 17  91  ?   ?   ?   A . n 
A 1 18  ASP 18  92  ?   ?   ?   A . n 
A 1 19  PRO 19  93  ?   ?   ?   A . n 
A 1 20  ALA 20  94  ?   ?   ?   A . n 
A 1 21  SER 21  95  ?   ?   ?   A . n 
A 1 22  VAL 22  96  96  VAL VAL A . n 
A 1 23  ARG 23  97  97  ARG ARG A . n 
A 1 24  LEU 24  98  98  LEU LEU A . n 
A 1 25  THR 25  99  99  THR THR A . n 
A 1 26  TRP 26  100 100 TRP TRP A . n 
A 1 27  ASN 27  101 101 ASN ASN A . n 
A 1 28  LYS 28  102 102 LYS LYS A . n 
A 1 29  SER 29  103 103 SER SER A . n 
A 1 30  PRO 30  104 104 PRO PRO A . n 
A 1 31  LYS 31  105 105 LYS LYS A . n 
A 1 32  SER 32  106 106 SER SER A . n 
A 1 33  VAL 33  107 107 VAL VAL A . n 
A 1 34  LEU 34  108 108 LEU LEU A . n 
A 1 35  VAL 35  109 109 VAL VAL A . n 
A 1 36  ILE 36  110 110 ILE ILE A . n 
A 1 37  LYS 37  111 111 LYS LYS A . n 
A 1 38  LYS 38  112 112 LYS LYS A . n 
A 1 39  MET 39  113 113 MET MET A . n 
A 1 40  ARG 40  114 114 ARG ARG A . n 
A 1 41  ASP 41  115 115 ASP ASP A . n 
A 1 42  ALA 42  116 116 ALA ALA A . n 
A 1 43  SER 43  117 117 SER SER A . n 
A 1 44  LEU 44  118 118 LEU LEU A . n 
A 1 45  LEU 45  119 119 LEU LEU A . n 
A 1 46  GLN 46  120 120 GLN GLN A . n 
A 1 47  PRO 47  121 121 PRO PRO A . n 
A 1 48  PHE 48  122 122 PHE PHE A . n 
A 1 49  LYS 49  123 123 LYS LYS A . n 
A 1 50  GLU 50  124 124 GLU GLU A . n 
A 1 51  LEU 51  125 125 LEU LEU A . n 
A 1 52  CYS 52  126 126 CYS CYS A . n 
A 1 53  THR 53  127 127 THR THR A . n 
A 1 54  HIS 54  128 128 HIS HIS A . n 
A 1 55  LEU 55  129 129 LEU LEU A . n 
A 1 56  MET 56  130 130 MET MET A . n 
A 1 57  GLU 57  131 131 GLU GLU A . n 
A 1 58  GLU 58  132 132 GLU GLU A . n 
A 1 59  ASN 59  133 133 ASN ASN A . n 
A 1 60  MET 60  134 134 MET MET A . n 
A 1 61  ILE 61  135 135 ILE ILE A . n 
A 1 62  VAL 62  136 136 VAL VAL A . n 
A 1 63  TYR 63  137 137 TYR TYR A . n 
A 1 64  VAL 64  138 138 VAL VAL A . n 
A 1 65  GLU 65  139 139 GLU GLU A . n 
A 1 66  LYS 66  140 140 LYS LYS A . n 
A 1 67  LYS 67  141 141 LYS LYS A . n 
A 1 68  VAL 68  142 142 VAL VAL A . n 
A 1 69  LEU 69  143 143 LEU LEU A . n 
A 1 70  GLU 70  144 144 GLU GLU A . n 
A 1 71  ASP 71  145 145 ASP ASP A . n 
A 1 72  PRO 72  146 146 PRO PRO A . n 
A 1 73  ALA 73  147 147 ALA ALA A . n 
A 1 74  ILE 74  148 148 ILE ILE A . n 
A 1 75  ALA 75  149 149 ALA ALA A . n 
A 1 76  SER 76  150 150 SER SER A . n 
A 1 77  ASP 77  151 151 ASP ASP A . n 
A 1 78  GLU 78  152 152 GLU GLU A . n 
A 1 79  SER 79  153 153 SER SER A . n 
A 1 80  PHE 80  154 154 PHE PHE A . n 
A 1 81  GLY 81  155 155 GLY GLY A . n 
A 1 82  ALA 82  156 156 ALA ALA A . n 
A 1 83  VAL 83  157 157 VAL VAL A . n 
A 1 84  LYS 84  158 158 LYS LYS A . n 
A 1 85  LYS 85  159 159 LYS LYS A . n 
A 1 86  LYS 86  160 160 LYS LYS A . n 
A 1 87  PHE 87  161 161 PHE PHE A . n 
A 1 88  THR 88  162 162 THR THR A . n 
A 1 89  THR 89  163 163 THR THR A . n 
A 1 90  PHE 90  164 164 PHE PHE A . n 
A 1 91  ARG 91  165 165 ARG ARG A . n 
A 1 92  GLU 92  166 166 GLU GLU A . n 
A 1 93  ASP 93  167 167 ASP ASP A . n 
A 1 94  TYR 94  168 168 TYR TYR A . n 
A 1 95  ASP 95  169 169 ASP ASP A . n 
A 1 96  ASP 96  170 170 ASP ASP A . n 
A 1 97  ILE 97  171 171 ILE ILE A . n 
A 1 98  SER 98  172 172 SER SER A . n 
A 1 99  ASN 99  173 173 ASN ASN A . n 
A 1 100 GLN 100 174 174 GLN GLN A . n 
A 1 101 ILE 101 175 175 ILE ILE A . n 
A 1 102 ASP 102 176 176 ASP ASP A . n 
A 1 103 PHE 103 177 177 PHE PHE A . n 
A 1 104 ILE 104 178 178 ILE ILE A . n 
A 1 105 ILE 105 179 179 ILE ILE A . n 
A 1 106 CYS 106 180 180 CYS CYS A . n 
A 1 107 LEU 107 181 181 LEU LEU A . n 
A 1 108 GLY 108 182 182 GLY GLY A . n 
A 1 109 GLY 109 183 183 GLY GLY A . n 
A 1 110 ASP 110 184 184 ASP ASP A . n 
A 1 111 GLY 111 185 185 GLY GLY A . n 
A 1 112 THR 112 186 186 THR THR A . n 
A 1 113 LEU 113 187 187 LEU LEU A . n 
A 1 114 LEU 114 188 188 LEU LEU A . n 
A 1 115 TYR 115 189 189 TYR TYR A . n 
A 1 116 ALA 116 190 190 ALA ALA A . n 
A 1 117 SER 117 191 191 SER SER A . n 
A 1 118 SER 118 192 192 SER SER A . n 
A 1 119 LEU 119 193 193 LEU LEU A . n 
A 1 120 PHE 120 194 194 PHE PHE A . n 
A 1 121 GLN 121 195 195 GLN GLN A . n 
A 1 122 GLY 122 196 196 GLY GLY A . n 
A 1 123 SER 123 197 197 SER SER A . n 
A 1 124 VAL 124 198 198 VAL VAL A . n 
A 1 125 PRO 125 199 199 PRO PRO A . n 
A 1 126 PRO 126 200 200 PRO PRO A . n 
A 1 127 VAL 127 201 201 VAL VAL A . n 
A 1 128 MET 128 202 202 MET MET A . n 
A 1 129 ALA 129 203 203 ALA ALA A . n 
A 1 130 PHE 130 204 204 PHE PHE A . n 
A 1 131 HIS 131 205 205 HIS HIS A . n 
A 1 132 LEU 132 206 206 LEU LEU A . n 
A 1 133 GLY 133 207 207 GLY GLY A . n 
A 1 134 SER 134 208 208 SER SER A . n 
A 1 135 LEU 135 209 209 LEU LEU A . n 
A 1 136 GLY 136 210 210 GLY GLY A . n 
A 1 137 PHE 137 211 211 PHE PHE A . n 
A 1 138 LEU 138 212 212 LEU LEU A . n 
A 1 139 THR 139 213 213 THR THR A . n 
A 1 140 PRO 140 214 214 PRO PRO A . n 
A 1 141 PHE 141 215 215 PHE PHE A . n 
A 1 142 SER 142 216 216 SER SER A . n 
A 1 143 PHE 143 217 217 PHE PHE A . n 
A 1 144 GLU 144 218 218 GLU GLU A . n 
A 1 145 ASN 145 219 219 ASN ASN A . n 
A 1 146 PHE 146 220 220 PHE PHE A . n 
A 1 147 GLN 147 221 221 GLN GLN A . n 
A 1 148 SER 148 222 222 SER SER A . n 
A 1 149 GLN 149 223 223 GLN GLN A . n 
A 1 150 VAL 150 224 224 VAL VAL A . n 
A 1 151 THR 151 225 225 THR THR A . n 
A 1 152 GLN 152 226 226 GLN GLN A . n 
A 1 153 VAL 153 227 227 VAL VAL A . n 
A 1 154 ILE 154 228 228 ILE ILE A . n 
A 1 155 GLU 155 229 229 GLU GLU A . n 
A 1 156 GLY 156 230 230 GLY GLY A . n 
A 1 157 ASN 157 231 231 ASN ASN A . n 
A 1 158 ALA 158 232 232 ALA ALA A . n 
A 1 159 ALA 159 233 233 ALA ALA A . n 
A 1 160 VAL 160 234 234 VAL VAL A . n 
A 1 161 VAL 161 235 235 VAL VAL A . n 
A 1 162 LEU 162 236 236 LEU LEU A . n 
A 1 163 ARG 163 237 237 ARG ARG A . n 
A 1 164 SER 164 238 238 SER SER A . n 
A 1 165 ARG 165 239 239 ARG ARG A . n 
A 1 166 LEU 166 240 240 LEU LEU A . n 
A 1 167 LYS 167 241 241 LYS LYS A . n 
A 1 168 VAL 168 242 242 VAL VAL A . n 
A 1 169 ARG 169 243 243 ARG ARG A . n 
A 1 170 VAL 170 244 244 VAL VAL A . n 
A 1 171 VAL 171 245 245 VAL VAL A . n 
A 1 172 LYS 172 246 246 LYS LYS A . n 
A 1 173 GLU 173 247 ?   ?   ?   A . n 
A 1 174 LEU 174 248 ?   ?   ?   A . n 
A 1 175 ARG 175 249 ?   ?   ?   A . n 
A 1 176 GLY 176 250 ?   ?   ?   A . n 
A 1 177 LYS 177 251 ?   ?   ?   A . n 
A 1 178 LYS 178 252 ?   ?   ?   A . n 
A 1 179 THR 179 253 ?   ?   ?   A . n 
A 1 180 ALA 180 254 ?   ?   ?   A . n 
A 1 181 VAL 181 255 ?   ?   ?   A . n 
A 1 182 HIS 182 256 ?   ?   ?   A . n 
A 1 183 ASN 183 257 ?   ?   ?   A . n 
A 1 184 GLY 184 258 ?   ?   ?   A . n 
A 1 185 LEU 185 259 ?   ?   ?   A . n 
A 1 186 GLY 186 260 ?   ?   ?   A . n 
A 1 187 GLU 187 261 ?   ?   ?   A . n 
A 1 188 ASN 188 262 ?   ?   ?   A . n 
A 1 189 GLY 189 263 ?   ?   ?   A . n 
A 1 190 SER 190 264 ?   ?   ?   A . n 
A 1 191 GLN 191 265 ?   ?   ?   A . n 
A 1 192 ALA 192 266 ?   ?   ?   A . n 
A 1 193 ALA 193 267 ?   ?   ?   A . n 
A 1 194 GLY 194 268 ?   ?   ?   A . n 
A 1 195 LEU 195 269 ?   ?   ?   A . n 
A 1 196 ASP 196 270 ?   ?   ?   A . n 
A 1 197 MET 197 271 ?   ?   ?   A . n 
A 1 198 ASP 198 272 ?   ?   ?   A . n 
A 1 199 VAL 199 273 ?   ?   ?   A . n 
A 1 200 GLY 200 274 ?   ?   ?   A . n 
A 1 201 LYS 201 275 ?   ?   ?   A . n 
A 1 202 GLN 202 276 ?   ?   ?   A . n 
A 1 203 ALA 203 277 277 ALA ALA A . n 
A 1 204 MET 204 278 278 MET MET A . n 
A 1 205 GLN 205 279 279 GLN GLN A . n 
A 1 206 TYR 206 280 280 TYR TYR A . n 
A 1 207 GLN 207 281 281 GLN GLN A . n 
A 1 208 VAL 208 282 282 VAL VAL A . n 
A 1 209 LEU 209 283 283 LEU LEU A . n 
A 1 210 ASN 210 284 284 ASN ASN A . n 
A 1 211 GLU 211 285 285 GLU GLU A . n 
A 1 212 VAL 212 286 286 VAL VAL A . n 
A 1 213 VAL 213 287 287 VAL VAL A . n 
A 1 214 ILE 214 288 288 ILE ILE A . n 
A 1 215 ASP 215 289 289 ASP ASP A . n 
A 1 216 ARG 216 290 290 ARG ARG A . n 
A 1 217 GLY 217 291 291 GLY GLY A . n 
A 1 218 PRO 218 292 292 PRO PRO A . n 
A 1 219 SER 219 293 293 SER SER A . n 
A 1 220 SER 220 294 294 SER SER A . n 
A 1 221 TYR 221 295 295 TYR TYR A . n 
A 1 222 LEU 222 296 296 LEU LEU A . n 
A 1 223 SER 223 297 297 SER SER A . n 
A 1 224 ASN 224 298 298 ASN ASN A . n 
A 1 225 VAL 225 299 299 VAL VAL A . n 
A 1 226 ASP 226 300 300 ASP ASP A . n 
A 1 227 VAL 227 301 301 VAL VAL A . n 
A 1 228 TYR 228 302 302 TYR TYR A . n 
A 1 229 LEU 229 303 303 LEU LEU A . n 
A 1 230 ASP 230 304 304 ASP ASP A . n 
A 1 231 GLY 231 305 305 GLY GLY A . n 
A 1 232 HIS 232 306 306 HIS HIS A . n 
A 1 233 LEU 233 307 307 LEU LEU A . n 
A 1 234 ILE 234 308 308 ILE ILE A . n 
A 1 235 THR 235 309 309 THR THR A . n 
A 1 236 THR 236 310 310 THR THR A . n 
A 1 237 VAL 237 311 311 VAL VAL A . n 
A 1 238 GLN 238 312 312 GLN GLN A . n 
A 1 239 GLY 239 313 313 GLY GLY A . n 
A 1 240 ASP 240 314 314 ASP ASP A . n 
A 1 241 GLY 241 315 315 GLY GLY A . n 
A 1 242 VAL 242 316 316 VAL VAL A . n 
A 1 243 ILE 243 317 317 ILE ILE A . n 
A 1 244 VAL 244 318 318 VAL VAL A . n 
A 1 245 SER 245 319 319 SER SER A . n 
A 1 246 THR 246 320 320 THR THR A . n 
A 1 247 PRO 247 321 321 PRO PRO A . n 
A 1 248 THR 248 322 322 THR THR A . n 
A 1 249 GLY 249 323 323 GLY GLY A . n 
A 1 250 SER 250 324 324 SER SER A . n 
A 1 251 THR 251 325 325 THR THR A . n 
A 1 252 ALA 252 326 326 ALA ALA A . n 
A 1 253 TYR 253 327 327 TYR TYR A . n 
A 1 254 ALA 254 328 328 ALA ALA A . n 
A 1 255 ALA 255 329 329 ALA ALA A . n 
A 1 256 ALA 256 330 330 ALA ALA A . n 
A 1 257 ALA 257 331 331 ALA ALA A . n 
A 1 258 GLY 258 332 332 GLY GLY A . n 
A 1 259 ALA 259 333 333 ALA ALA A . n 
A 1 260 SER 260 334 334 SER SER A . n 
A 1 261 MET 261 335 335 MET MET A . n 
A 1 262 ILE 262 336 336 ILE ILE A . n 
A 1 263 HIS 263 337 337 HIS HIS A . n 
A 1 264 PRO 264 338 338 PRO PRO A . n 
A 1 265 ASN 265 339 339 ASN ASN A . n 
A 1 266 VAL 266 340 340 VAL VAL A . n 
A 1 267 PRO 267 341 341 PRO PRO A . n 
A 1 268 ALA 268 342 342 ALA ALA A . n 
A 1 269 ILE 269 343 343 ILE ILE A . n 
A 1 270 MET 270 344 344 MET MET A . n 
A 1 271 ILE 271 345 345 ILE ILE A . n 
A 1 272 THR 272 346 346 THR THR A . n 
A 1 273 PRO 273 347 347 PRO PRO A . n 
A 1 274 ILE 274 348 348 ILE ILE A . n 
A 1 275 CYS 275 349 349 CYS CYS A . n 
A 1 276 PRO 276 350 350 PRO PRO A . n 
A 1 277 HIS 277 351 351 HIS HIS A . n 
A 1 278 SER 278 352 352 SER SER A . n 
A 1 279 LEU 279 353 353 LEU LEU A . n 
A 1 280 SER 280 354 354 SER SER A . n 
A 1 281 PHE 281 355 355 PHE PHE A . n 
A 1 282 ARG 282 356 356 ARG ARG A . n 
A 1 283 PRO 283 357 357 PRO PRO A . n 
A 1 284 ILE 284 358 358 ILE ILE A . n 
A 1 285 VAL 285 359 359 VAL VAL A . n 
A 1 286 VAL 286 360 360 VAL VAL A . n 
A 1 287 PRO 287 361 361 PRO PRO A . n 
A 1 288 ALA 288 362 362 ALA ALA A . n 
A 1 289 GLY 289 363 363 GLY GLY A . n 
A 1 290 VAL 290 364 364 VAL VAL A . n 
A 1 291 GLU 291 365 365 GLU GLU A . n 
A 1 292 LEU 292 366 366 LEU LEU A . n 
A 1 293 LYS 293 367 367 LYS LYS A . n 
A 1 294 ILE 294 368 368 ILE ILE A . n 
A 1 295 MET 295 369 369 MET MET A . n 
A 1 296 LEU 296 370 370 LEU LEU A . n 
A 1 297 SER 297 371 371 SER SER A . n 
A 1 298 PRO 298 372 372 PRO PRO A . n 
A 1 299 GLU 299 373 373 GLU GLU A . n 
A 1 300 ALA 300 374 374 ALA ALA A . n 
A 1 301 ARG 301 375 375 ARG ARG A . n 
A 1 302 ASN 302 376 376 ASN ASN A . n 
A 1 303 THR 303 377 377 THR THR A . n 
A 1 304 ALA 304 378 378 ALA ALA A . n 
A 1 305 TRP 305 379 379 TRP TRP A . n 
A 1 306 VAL 306 380 380 VAL VAL A . n 
A 1 307 SER 307 381 381 SER SER A . n 
A 1 308 PHE 308 382 382 PHE PHE A . n 
A 1 309 ASP 309 383 383 ASP ASP A . n 
A 1 310 GLY 310 384 384 GLY GLY A . n 
A 1 311 ARG 311 385 385 ARG ARG A . n 
A 1 312 LYS 312 386 386 LYS LYS A . n 
A 1 313 ARG 313 387 387 ARG ARG A . n 
A 1 314 GLN 314 388 388 GLN GLN A . n 
A 1 315 GLU 315 389 389 GLU GLU A . n 
A 1 316 ILE 316 390 390 ILE ILE A . n 
A 1 317 ARG 317 391 391 ARG ARG A . n 
A 1 318 HIS 318 392 392 HIS HIS A . n 
A 1 319 GLY 319 393 393 GLY GLY A . n 
A 1 320 ASP 320 394 394 ASP ASP A . n 
A 1 321 SER 321 395 395 SER SER A . n 
A 1 322 ILE 322 396 396 ILE ILE A . n 
A 1 323 SER 323 397 397 SER SER A . n 
A 1 324 ILE 324 398 398 ILE ILE A . n 
A 1 325 THR 325 399 399 THR THR A . n 
A 1 326 THR 326 400 400 THR THR A . n 
A 1 327 SER 327 401 401 SER SER A . n 
A 1 328 THR 328 402 402 THR THR A . n 
A 1 329 TYR 329 403 403 TYR TYR A . n 
A 1 330 PRO 330 404 404 PRO PRO A . n 
A 1 331 LEU 331 405 405 LEU LEU A . n 
A 1 332 PRO 332 406 406 PRO PRO A . n 
A 1 333 SER 333 407 407 SER SER A . n 
A 1 334 ILE 334 408 408 ILE ILE A . n 
A 1 335 CYS 335 409 409 CYS CYS A . n 
A 1 336 VAL 336 410 410 VAL VAL A . n 
A 1 337 ARG 337 411 411 ARG ARG A . n 
A 1 338 ASP 338 412 412 ASP ASP A . n 
A 1 339 PRO 339 413 413 PRO PRO A . n 
A 1 340 VAL 340 414 414 VAL VAL A . n 
A 1 341 SER 341 415 415 SER SER A . n 
A 1 342 ASP 342 416 416 ASP ASP A . n 
A 1 343 TRP 343 417 417 TRP TRP A . n 
A 1 344 PHE 344 418 418 PHE PHE A . n 
A 1 345 GLU 345 419 419 GLU GLU A . n 
A 1 346 SER 346 420 420 SER SER A . n 
A 1 347 LEU 347 421 421 LEU LEU A . n 
A 1 348 ALA 348 422 422 ALA ALA A . n 
A 1 349 GLN 349 423 423 GLN GLN A . n 
A 1 350 CYS 350 424 424 CYS CYS A . n 
A 1 351 LEU 351 425 425 LEU LEU A . n 
A 1 352 HIS 352 426 426 HIS HIS A . n 
A 1 353 TRP 353 427 427 TRP TRP A . n 
A 1 354 ASN 354 428 428 ASN ASN A . n 
A 1 355 VAL 355 429 429 VAL VAL A . n 
A 1 356 ARG 356 430 430 ARG ARG A . n 
A 1 357 LYS 357 431 ?   ?   ?   A . n 
A 1 358 LYS 358 432 ?   ?   ?   A . n 
A 1 359 GLN 359 433 ?   ?   ?   A . n 
A 1 360 ALA 360 434 ?   ?   ?   A . n 
A 1 361 HIS 361 435 ?   ?   ?   A . n 
A 1 362 PHE 362 436 ?   ?   ?   A . n 
A 1 363 GLU 363 437 ?   ?   ?   A . n 
A 1 364 LEU 364 438 ?   ?   ?   A . n 
A 1 365 GLY 365 439 ?   ?   ?   A . n 
A 1 366 LEU 366 440 ?   ?   ?   A . n 
A 1 367 GLU 367 441 ?   ?   ?   A . n 
A 1 368 HIS 368 442 ?   ?   ?   A . n 
A 1 369 HIS 369 443 ?   ?   ?   A . n 
A 1 370 HIS 370 444 ?   ?   ?   A . n 
A 1 371 HIS 371 445 ?   ?   ?   A . n 
A 1 372 HIS 372 446 ?   ?   ?   A . n 
A 1 373 HIS 373 447 ?   ?   ?   A . n 
B 1 1   MET 1   67  ?   ?   ?   B . n 
B 1 2   PRO 2   68  ?   ?   ?   B . n 
B 1 3   SER 3   69  ?   ?   ?   B . n 
B 1 4   PRO 4   70  ?   ?   ?   B . n 
B 1 5   VAL 5   71  ?   ?   ?   B . n 
B 1 6   THR 6   72  ?   ?   ?   B . n 
B 1 7   THR 7   73  73  THR THR B . n 
B 1 8   PHE 8   74  74  PHE PHE B . n 
B 1 9   GLY 9   75  75  GLY GLY B . n 
B 1 10  PRO 10  76  76  PRO PRO B . n 
B 1 11  LYS 11  77  77  LYS LYS B . n 
B 1 12  ALA 12  78  78  ALA ALA B . n 
B 1 13  THR 13  79  79  THR THR B . n 
B 1 14  VAL 14  80  80  VAL VAL B . n 
B 1 15  GLU 15  89  ?   ?   ?   B . n 
B 1 16  THR 16  90  ?   ?   ?   B . n 
B 1 17  GLN 17  91  ?   ?   ?   B . n 
B 1 18  ASP 18  92  ?   ?   ?   B . n 
B 1 19  PRO 19  93  ?   ?   ?   B . n 
B 1 20  ALA 20  94  ?   ?   ?   B . n 
B 1 21  SER 21  95  ?   ?   ?   B . n 
B 1 22  VAL 22  96  96  VAL VAL B . n 
B 1 23  ARG 23  97  97  ARG ARG B . n 
B 1 24  LEU 24  98  98  LEU LEU B . n 
B 1 25  THR 25  99  99  THR THR B . n 
B 1 26  TRP 26  100 100 TRP TRP B . n 
B 1 27  ASN 27  101 101 ASN ASN B . n 
B 1 28  LYS 28  102 102 LYS LYS B . n 
B 1 29  SER 29  103 103 SER SER B . n 
B 1 30  PRO 30  104 104 PRO PRO B . n 
B 1 31  LYS 31  105 105 LYS LYS B . n 
B 1 32  SER 32  106 106 SER SER B . n 
B 1 33  VAL 33  107 107 VAL VAL B . n 
B 1 34  LEU 34  108 108 LEU LEU B . n 
B 1 35  VAL 35  109 109 VAL VAL B . n 
B 1 36  ILE 36  110 110 ILE ILE B . n 
B 1 37  LYS 37  111 111 LYS LYS B . n 
B 1 38  LYS 38  112 112 LYS LYS B . n 
B 1 39  MET 39  113 113 MET MET B . n 
B 1 40  ARG 40  114 114 ARG ARG B . n 
B 1 41  ASP 41  115 115 ASP ASP B . n 
B 1 42  ALA 42  116 116 ALA ALA B . n 
B 1 43  SER 43  117 117 SER SER B . n 
B 1 44  LEU 44  118 118 LEU LEU B . n 
B 1 45  LEU 45  119 119 LEU LEU B . n 
B 1 46  GLN 46  120 120 GLN GLN B . n 
B 1 47  PRO 47  121 121 PRO PRO B . n 
B 1 48  PHE 48  122 122 PHE PHE B . n 
B 1 49  LYS 49  123 123 LYS LYS B . n 
B 1 50  GLU 50  124 124 GLU GLU B . n 
B 1 51  LEU 51  125 125 LEU LEU B . n 
B 1 52  CYS 52  126 126 CYS CYS B . n 
B 1 53  THR 53  127 127 THR THR B . n 
B 1 54  HIS 54  128 128 HIS HIS B . n 
B 1 55  LEU 55  129 129 LEU LEU B . n 
B 1 56  MET 56  130 130 MET MET B . n 
B 1 57  GLU 57  131 131 GLU GLU B . n 
B 1 58  GLU 58  132 132 GLU GLU B . n 
B 1 59  ASN 59  133 133 ASN ASN B . n 
B 1 60  MET 60  134 134 MET MET B . n 
B 1 61  ILE 61  135 135 ILE ILE B . n 
B 1 62  VAL 62  136 136 VAL VAL B . n 
B 1 63  TYR 63  137 137 TYR TYR B . n 
B 1 64  VAL 64  138 138 VAL VAL B . n 
B 1 65  GLU 65  139 139 GLU GLU B . n 
B 1 66  LYS 66  140 140 LYS LYS B . n 
B 1 67  LYS 67  141 141 LYS LYS B . n 
B 1 68  VAL 68  142 142 VAL VAL B . n 
B 1 69  LEU 69  143 143 LEU LEU B . n 
B 1 70  GLU 70  144 144 GLU GLU B . n 
B 1 71  ASP 71  145 145 ASP ASP B . n 
B 1 72  PRO 72  146 146 PRO PRO B . n 
B 1 73  ALA 73  147 147 ALA ALA B . n 
B 1 74  ILE 74  148 148 ILE ILE B . n 
B 1 75  ALA 75  149 149 ALA ALA B . n 
B 1 76  SER 76  150 150 SER SER B . n 
B 1 77  ASP 77  151 151 ASP ASP B . n 
B 1 78  GLU 78  152 152 GLU GLU B . n 
B 1 79  SER 79  153 153 SER SER B . n 
B 1 80  PHE 80  154 154 PHE PHE B . n 
B 1 81  GLY 81  155 155 GLY GLY B . n 
B 1 82  ALA 82  156 156 ALA ALA B . n 
B 1 83  VAL 83  157 157 VAL VAL B . n 
B 1 84  LYS 84  158 158 LYS LYS B . n 
B 1 85  LYS 85  159 159 LYS LYS B . n 
B 1 86  LYS 86  160 160 LYS LYS B . n 
B 1 87  PHE 87  161 161 PHE PHE B . n 
B 1 88  THR 88  162 162 THR THR B . n 
B 1 89  THR 89  163 163 THR THR B . n 
B 1 90  PHE 90  164 164 PHE PHE B . n 
B 1 91  ARG 91  165 165 ARG ARG B . n 
B 1 92  GLU 92  166 ?   ?   ?   B . n 
B 1 93  ASP 93  167 ?   ?   ?   B . n 
B 1 94  TYR 94  168 ?   ?   ?   B . n 
B 1 95  ASP 95  169 ?   ?   ?   B . n 
B 1 96  ASP 96  170 ?   ?   ?   B . n 
B 1 97  ILE 97  171 ?   ?   ?   B . n 
B 1 98  SER 98  172 172 SER SER B . n 
B 1 99  ASN 99  173 173 ASN ASN B . n 
B 1 100 GLN 100 174 174 GLN GLN B . n 
B 1 101 ILE 101 175 175 ILE ILE B . n 
B 1 102 ASP 102 176 176 ASP ASP B . n 
B 1 103 PHE 103 177 177 PHE PHE B . n 
B 1 104 ILE 104 178 178 ILE ILE B . n 
B 1 105 ILE 105 179 179 ILE ILE B . n 
B 1 106 CYS 106 180 180 CYS CYS B . n 
B 1 107 LEU 107 181 181 LEU LEU B . n 
B 1 108 GLY 108 182 182 GLY GLY B . n 
B 1 109 GLY 109 183 183 GLY GLY B . n 
B 1 110 ASP 110 184 184 ASP ASP B . n 
B 1 111 GLY 111 185 185 GLY GLY B . n 
B 1 112 THR 112 186 186 THR THR B . n 
B 1 113 LEU 113 187 187 LEU LEU B . n 
B 1 114 LEU 114 188 188 LEU LEU B . n 
B 1 115 TYR 115 189 189 TYR TYR B . n 
B 1 116 ALA 116 190 190 ALA ALA B . n 
B 1 117 SER 117 191 191 SER SER B . n 
B 1 118 SER 118 192 192 SER SER B . n 
B 1 119 LEU 119 193 193 LEU LEU B . n 
B 1 120 PHE 120 194 194 PHE PHE B . n 
B 1 121 GLN 121 195 195 GLN GLN B . n 
B 1 122 GLY 122 196 196 GLY GLY B . n 
B 1 123 SER 123 197 197 SER SER B . n 
B 1 124 VAL 124 198 198 VAL VAL B . n 
B 1 125 PRO 125 199 199 PRO PRO B . n 
B 1 126 PRO 126 200 200 PRO PRO B . n 
B 1 127 VAL 127 201 201 VAL VAL B . n 
B 1 128 MET 128 202 202 MET MET B . n 
B 1 129 ALA 129 203 203 ALA ALA B . n 
B 1 130 PHE 130 204 204 PHE PHE B . n 
B 1 131 HIS 131 205 205 HIS HIS B . n 
B 1 132 LEU 132 206 206 LEU LEU B . n 
B 1 133 GLY 133 207 207 GLY GLY B . n 
B 1 134 SER 134 208 208 SER SER B . n 
B 1 135 LEU 135 209 209 LEU LEU B . n 
B 1 136 GLY 136 210 210 GLY GLY B . n 
B 1 137 PHE 137 211 211 PHE PHE B . n 
B 1 138 LEU 138 212 212 LEU LEU B . n 
B 1 139 THR 139 213 213 THR THR B . n 
B 1 140 PRO 140 214 214 PRO PRO B . n 
B 1 141 PHE 141 215 215 PHE PHE B . n 
B 1 142 SER 142 216 216 SER SER B . n 
B 1 143 PHE 143 217 217 PHE PHE B . n 
B 1 144 GLU 144 218 218 GLU GLU B . n 
B 1 145 ASN 145 219 219 ASN ASN B . n 
B 1 146 PHE 146 220 220 PHE PHE B . n 
B 1 147 GLN 147 221 221 GLN GLN B . n 
B 1 148 SER 148 222 222 SER SER B . n 
B 1 149 GLN 149 223 223 GLN GLN B . n 
B 1 150 VAL 150 224 224 VAL VAL B . n 
B 1 151 THR 151 225 225 THR THR B . n 
B 1 152 GLN 152 226 226 GLN GLN B . n 
B 1 153 VAL 153 227 227 VAL VAL B . n 
B 1 154 ILE 154 228 228 ILE ILE B . n 
B 1 155 GLU 155 229 229 GLU GLU B . n 
B 1 156 GLY 156 230 230 GLY GLY B . n 
B 1 157 ASN 157 231 231 ASN ASN B . n 
B 1 158 ALA 158 232 232 ALA ALA B . n 
B 1 159 ALA 159 233 233 ALA ALA B . n 
B 1 160 VAL 160 234 234 VAL VAL B . n 
B 1 161 VAL 161 235 235 VAL VAL B . n 
B 1 162 LEU 162 236 236 LEU LEU B . n 
B 1 163 ARG 163 237 237 ARG ARG B . n 
B 1 164 SER 164 238 238 SER SER B . n 
B 1 165 ARG 165 239 239 ARG ARG B . n 
B 1 166 LEU 166 240 240 LEU LEU B . n 
B 1 167 LYS 167 241 241 LYS LYS B . n 
B 1 168 VAL 168 242 242 VAL VAL B . n 
B 1 169 ARG 169 243 243 ARG ARG B . n 
B 1 170 VAL 170 244 244 VAL VAL B . n 
B 1 171 VAL 171 245 245 VAL VAL B . n 
B 1 172 LYS 172 246 246 LYS LYS B . n 
B 1 173 GLU 173 247 247 GLU GLU B . n 
B 1 174 LEU 174 248 ?   ?   ?   B . n 
B 1 175 ARG 175 249 ?   ?   ?   B . n 
B 1 176 GLY 176 250 ?   ?   ?   B . n 
B 1 177 LYS 177 251 ?   ?   ?   B . n 
B 1 178 LYS 178 252 ?   ?   ?   B . n 
B 1 179 THR 179 253 ?   ?   ?   B . n 
B 1 180 ALA 180 254 ?   ?   ?   B . n 
B 1 181 VAL 181 255 ?   ?   ?   B . n 
B 1 182 HIS 182 256 ?   ?   ?   B . n 
B 1 183 ASN 183 257 ?   ?   ?   B . n 
B 1 184 GLY 184 258 ?   ?   ?   B . n 
B 1 185 LEU 185 259 ?   ?   ?   B . n 
B 1 186 GLY 186 260 ?   ?   ?   B . n 
B 1 187 GLU 187 261 ?   ?   ?   B . n 
B 1 188 ASN 188 262 ?   ?   ?   B . n 
B 1 189 GLY 189 263 ?   ?   ?   B . n 
B 1 190 SER 190 264 ?   ?   ?   B . n 
B 1 191 GLN 191 265 ?   ?   ?   B . n 
B 1 192 ALA 192 266 ?   ?   ?   B . n 
B 1 193 ALA 193 267 ?   ?   ?   B . n 
B 1 194 GLY 194 268 ?   ?   ?   B . n 
B 1 195 LEU 195 269 ?   ?   ?   B . n 
B 1 196 ASP 196 270 ?   ?   ?   B . n 
B 1 197 MET 197 271 ?   ?   ?   B . n 
B 1 198 ASP 198 272 ?   ?   ?   B . n 
B 1 199 VAL 199 273 ?   ?   ?   B . n 
B 1 200 GLY 200 274 ?   ?   ?   B . n 
B 1 201 LYS 201 275 ?   ?   ?   B . n 
B 1 202 GLN 202 276 276 GLN ALA B . n 
B 1 203 ALA 203 277 277 ALA ALA B . n 
B 1 204 MET 204 278 278 MET MET B . n 
B 1 205 GLN 205 279 279 GLN GLN B . n 
B 1 206 TYR 206 280 280 TYR TYR B . n 
B 1 207 GLN 207 281 281 GLN GLN B . n 
B 1 208 VAL 208 282 282 VAL VAL B . n 
B 1 209 LEU 209 283 283 LEU LEU B . n 
B 1 210 ASN 210 284 284 ASN ASN B . n 
B 1 211 GLU 211 285 285 GLU GLU B . n 
B 1 212 VAL 212 286 286 VAL VAL B . n 
B 1 213 VAL 213 287 287 VAL VAL B . n 
B 1 214 ILE 214 288 288 ILE ILE B . n 
B 1 215 ASP 215 289 289 ASP ASP B . n 
B 1 216 ARG 216 290 290 ARG ARG B . n 
B 1 217 GLY 217 291 291 GLY GLY B . n 
B 1 218 PRO 218 292 292 PRO PRO B . n 
B 1 219 SER 219 293 293 SER SER B . n 
B 1 220 SER 220 294 294 SER SER B . n 
B 1 221 TYR 221 295 295 TYR TYR B . n 
B 1 222 LEU 222 296 296 LEU LEU B . n 
B 1 223 SER 223 297 297 SER SER B . n 
B 1 224 ASN 224 298 298 ASN ASN B . n 
B 1 225 VAL 225 299 299 VAL VAL B . n 
B 1 226 ASP 226 300 300 ASP ASP B . n 
B 1 227 VAL 227 301 301 VAL VAL B . n 
B 1 228 TYR 228 302 302 TYR TYR B . n 
B 1 229 LEU 229 303 303 LEU LEU B . n 
B 1 230 ASP 230 304 304 ASP ASP B . n 
B 1 231 GLY 231 305 305 GLY GLY B . n 
B 1 232 HIS 232 306 306 HIS HIS B . n 
B 1 233 LEU 233 307 307 LEU LEU B . n 
B 1 234 ILE 234 308 308 ILE ILE B . n 
B 1 235 THR 235 309 309 THR THR B . n 
B 1 236 THR 236 310 310 THR THR B . n 
B 1 237 VAL 237 311 311 VAL VAL B . n 
B 1 238 GLN 238 312 312 GLN GLN B . n 
B 1 239 GLY 239 313 313 GLY GLY B . n 
B 1 240 ASP 240 314 314 ASP ASP B . n 
B 1 241 GLY 241 315 315 GLY GLY B . n 
B 1 242 VAL 242 316 316 VAL VAL B . n 
B 1 243 ILE 243 317 317 ILE ILE B . n 
B 1 244 VAL 244 318 318 VAL VAL B . n 
B 1 245 SER 245 319 319 SER SER B . n 
B 1 246 THR 246 320 320 THR THR B . n 
B 1 247 PRO 247 321 321 PRO PRO B . n 
B 1 248 THR 248 322 322 THR THR B . n 
B 1 249 GLY 249 323 323 GLY GLY B . n 
B 1 250 SER 250 324 324 SER SER B . n 
B 1 251 THR 251 325 325 THR THR B . n 
B 1 252 ALA 252 326 326 ALA ALA B . n 
B 1 253 TYR 253 327 327 TYR TYR B . n 
B 1 254 ALA 254 328 328 ALA ALA B . n 
B 1 255 ALA 255 329 329 ALA ALA B . n 
B 1 256 ALA 256 330 330 ALA ALA B . n 
B 1 257 ALA 257 331 331 ALA ALA B . n 
B 1 258 GLY 258 332 332 GLY GLY B . n 
B 1 259 ALA 259 333 333 ALA ALA B . n 
B 1 260 SER 260 334 334 SER SER B . n 
B 1 261 MET 261 335 335 MET MET B . n 
B 1 262 ILE 262 336 336 ILE ILE B . n 
B 1 263 HIS 263 337 337 HIS HIS B . n 
B 1 264 PRO 264 338 338 PRO PRO B . n 
B 1 265 ASN 265 339 339 ASN ASN B . n 
B 1 266 VAL 266 340 340 VAL VAL B . n 
B 1 267 PRO 267 341 341 PRO PRO B . n 
B 1 268 ALA 268 342 342 ALA ALA B . n 
B 1 269 ILE 269 343 343 ILE ILE B . n 
B 1 270 MET 270 344 344 MET MET B . n 
B 1 271 ILE 271 345 345 ILE ILE B . n 
B 1 272 THR 272 346 346 THR THR B . n 
B 1 273 PRO 273 347 347 PRO PRO B . n 
B 1 274 ILE 274 348 348 ILE ILE B . n 
B 1 275 CYS 275 349 349 CYS CYS B . n 
B 1 276 PRO 276 350 350 PRO PRO B . n 
B 1 277 HIS 277 351 351 HIS HIS B . n 
B 1 278 SER 278 352 352 SER SER B . n 
B 1 279 LEU 279 353 353 LEU LEU B . n 
B 1 280 SER 280 354 354 SER SER B . n 
B 1 281 PHE 281 355 355 PHE PHE B . n 
B 1 282 ARG 282 356 356 ARG ARG B . n 
B 1 283 PRO 283 357 357 PRO PRO B . n 
B 1 284 ILE 284 358 358 ILE ILE B . n 
B 1 285 VAL 285 359 359 VAL VAL B . n 
B 1 286 VAL 286 360 360 VAL VAL B . n 
B 1 287 PRO 287 361 361 PRO PRO B . n 
B 1 288 ALA 288 362 362 ALA ALA B . n 
B 1 289 GLY 289 363 363 GLY GLY B . n 
B 1 290 VAL 290 364 364 VAL VAL B . n 
B 1 291 GLU 291 365 365 GLU GLU B . n 
B 1 292 LEU 292 366 366 LEU LEU B . n 
B 1 293 LYS 293 367 367 LYS LYS B . n 
B 1 294 ILE 294 368 368 ILE ILE B . n 
B 1 295 MET 295 369 369 MET MET B . n 
B 1 296 LEU 296 370 370 LEU LEU B . n 
B 1 297 SER 297 371 371 SER SER B . n 
B 1 298 PRO 298 372 372 PRO PRO B . n 
B 1 299 GLU 299 373 373 GLU GLU B . n 
B 1 300 ALA 300 374 374 ALA ALA B . n 
B 1 301 ARG 301 375 375 ARG ARG B . n 
B 1 302 ASN 302 376 376 ASN ASN B . n 
B 1 303 THR 303 377 377 THR THR B . n 
B 1 304 ALA 304 378 378 ALA ALA B . n 
B 1 305 TRP 305 379 379 TRP TRP B . n 
B 1 306 VAL 306 380 380 VAL VAL B . n 
B 1 307 SER 307 381 381 SER SER B . n 
B 1 308 PHE 308 382 382 PHE PHE B . n 
B 1 309 ASP 309 383 383 ASP ASP B . n 
B 1 310 GLY 310 384 384 GLY GLY B . n 
B 1 311 ARG 311 385 385 ARG ARG B . n 
B 1 312 LYS 312 386 386 LYS LYS B . n 
B 1 313 ARG 313 387 387 ARG ARG B . n 
B 1 314 GLN 314 388 388 GLN GLN B . n 
B 1 315 GLU 315 389 389 GLU GLU B . n 
B 1 316 ILE 316 390 390 ILE ILE B . n 
B 1 317 ARG 317 391 391 ARG ARG B . n 
B 1 318 HIS 318 392 392 HIS HIS B . n 
B 1 319 GLY 319 393 393 GLY GLY B . n 
B 1 320 ASP 320 394 394 ASP ASP B . n 
B 1 321 SER 321 395 395 SER SER B . n 
B 1 322 ILE 322 396 396 ILE ILE B . n 
B 1 323 SER 323 397 397 SER SER B . n 
B 1 324 ILE 324 398 398 ILE ILE B . n 
B 1 325 THR 325 399 399 THR THR B . n 
B 1 326 THR 326 400 400 THR THR B . n 
B 1 327 SER 327 401 401 SER SER B . n 
B 1 328 THR 328 402 402 THR THR B . n 
B 1 329 TYR 329 403 403 TYR TYR B . n 
B 1 330 PRO 330 404 404 PRO PRO B . n 
B 1 331 LEU 331 405 405 LEU LEU B . n 
B 1 332 PRO 332 406 406 PRO PRO B . n 
B 1 333 SER 333 407 407 SER SER B . n 
B 1 334 ILE 334 408 408 ILE ILE B . n 
B 1 335 CYS 335 409 409 CYS CYS B . n 
B 1 336 VAL 336 410 410 VAL VAL B . n 
B 1 337 ARG 337 411 411 ARG ARG B . n 
B 1 338 ASP 338 412 412 ASP ASP B . n 
B 1 339 PRO 339 413 413 PRO PRO B . n 
B 1 340 VAL 340 414 414 VAL VAL B . n 
B 1 341 SER 341 415 415 SER SER B . n 
B 1 342 ASP 342 416 416 ASP ASP B . n 
B 1 343 TRP 343 417 417 TRP TRP B . n 
B 1 344 PHE 344 418 418 PHE PHE B . n 
B 1 345 GLU 345 419 419 GLU GLU B . n 
B 1 346 SER 346 420 420 SER SER B . n 
B 1 347 LEU 347 421 421 LEU LEU B . n 
B 1 348 ALA 348 422 422 ALA ALA B . n 
B 1 349 GLN 349 423 423 GLN GLN B . n 
B 1 350 CYS 350 424 424 CYS CYS B . n 
B 1 351 LEU 351 425 425 LEU LEU B . n 
B 1 352 HIS 352 426 426 HIS HIS B . n 
B 1 353 TRP 353 427 427 TRP TRP B . n 
B 1 354 ASN 354 428 428 ASN ASN B . n 
B 1 355 VAL 355 429 429 VAL VAL B . n 
B 1 356 ARG 356 430 430 ARG ARG B . n 
B 1 357 LYS 357 431 ?   ?   ?   B . n 
B 1 358 LYS 358 432 ?   ?   ?   B . n 
B 1 359 GLN 359 433 ?   ?   ?   B . n 
B 1 360 ALA 360 434 ?   ?   ?   B . n 
B 1 361 HIS 361 435 ?   ?   ?   B . n 
B 1 362 PHE 362 436 ?   ?   ?   B . n 
B 1 363 GLU 363 437 ?   ?   ?   B . n 
B 1 364 LEU 364 438 ?   ?   ?   B . n 
B 1 365 GLY 365 439 ?   ?   ?   B . n 
B 1 366 LEU 366 440 ?   ?   ?   B . n 
B 1 367 GLU 367 441 ?   ?   ?   B . n 
B 1 368 HIS 368 442 ?   ?   ?   B . n 
B 1 369 HIS 369 443 ?   ?   ?   B . n 
B 1 370 HIS 370 444 ?   ?   ?   B . n 
B 1 371 HIS 371 445 ?   ?   ?   B . n 
B 1 372 HIS 372 446 ?   ?   ?   B . n 
B 1 373 HIS 373 447 ?   ?   ?   B . n 
C 1 1   MET 1   67  ?   ?   ?   C . n 
C 1 2   PRO 2   68  ?   ?   ?   C . n 
C 1 3   SER 3   69  ?   ?   ?   C . n 
C 1 4   PRO 4   70  ?   ?   ?   C . n 
C 1 5   VAL 5   71  ?   ?   ?   C . n 
C 1 6   THR 6   72  ?   ?   ?   C . n 
C 1 7   THR 7   73  ?   ?   ?   C . n 
C 1 8   PHE 8   74  74  PHE PHE C . n 
C 1 9   GLY 9   75  75  GLY GLY C . n 
C 1 10  PRO 10  76  76  PRO PRO C . n 
C 1 11  LYS 11  77  77  LYS LYS C . n 
C 1 12  ALA 12  78  78  ALA ALA C . n 
C 1 13  THR 13  87  ?   ?   ?   C . n 
C 1 14  VAL 14  88  ?   ?   ?   C . n 
C 1 15  GLU 15  89  ?   ?   ?   C . n 
C 1 16  THR 16  90  ?   ?   ?   C . n 
C 1 17  GLN 17  91  ?   ?   ?   C . n 
C 1 18  ASP 18  92  ?   ?   ?   C . n 
C 1 19  PRO 19  93  ?   ?   ?   C . n 
C 1 20  ALA 20  94  ?   ?   ?   C . n 
C 1 21  SER 21  95  ?   ?   ?   C . n 
C 1 22  VAL 22  96  96  VAL VAL C . n 
C 1 23  ARG 23  97  97  ARG ARG C . n 
C 1 24  LEU 24  98  98  LEU LEU C . n 
C 1 25  THR 25  99  99  THR THR C . n 
C 1 26  TRP 26  100 100 TRP TRP C . n 
C 1 27  ASN 27  101 101 ASN ASN C . n 
C 1 28  LYS 28  102 102 LYS LYS C . n 
C 1 29  SER 29  103 103 SER SER C . n 
C 1 30  PRO 30  104 104 PRO PRO C . n 
C 1 31  LYS 31  105 105 LYS LYS C . n 
C 1 32  SER 32  106 106 SER SER C . n 
C 1 33  VAL 33  107 107 VAL VAL C . n 
C 1 34  LEU 34  108 108 LEU LEU C . n 
C 1 35  VAL 35  109 109 VAL VAL C . n 
C 1 36  ILE 36  110 110 ILE ILE C . n 
C 1 37  LYS 37  111 111 LYS LYS C . n 
C 1 38  LYS 38  112 112 LYS LYS C . n 
C 1 39  MET 39  113 113 MET MET C . n 
C 1 40  ARG 40  114 114 ARG ARG C . n 
C 1 41  ASP 41  115 115 ASP ASP C . n 
C 1 42  ALA 42  116 116 ALA ALA C . n 
C 1 43  SER 43  117 117 SER SER C . n 
C 1 44  LEU 44  118 118 LEU LEU C . n 
C 1 45  LEU 45  119 119 LEU LEU C . n 
C 1 46  GLN 46  120 120 GLN GLN C . n 
C 1 47  PRO 47  121 121 PRO PRO C . n 
C 1 48  PHE 48  122 122 PHE PHE C . n 
C 1 49  LYS 49  123 123 LYS LYS C . n 
C 1 50  GLU 50  124 124 GLU GLU C . n 
C 1 51  LEU 51  125 125 LEU LEU C . n 
C 1 52  CYS 52  126 126 CYS CYS C . n 
C 1 53  THR 53  127 127 THR THR C . n 
C 1 54  HIS 54  128 128 HIS HIS C . n 
C 1 55  LEU 55  129 129 LEU LEU C . n 
C 1 56  MET 56  130 130 MET MET C . n 
C 1 57  GLU 57  131 131 GLU GLU C . n 
C 1 58  GLU 58  132 132 GLU GLU C . n 
C 1 59  ASN 59  133 133 ASN ASN C . n 
C 1 60  MET 60  134 134 MET MET C . n 
C 1 61  ILE 61  135 135 ILE ILE C . n 
C 1 62  VAL 62  136 136 VAL VAL C . n 
C 1 63  TYR 63  137 137 TYR TYR C . n 
C 1 64  VAL 64  138 138 VAL VAL C . n 
C 1 65  GLU 65  139 139 GLU GLU C . n 
C 1 66  LYS 66  140 140 LYS LYS C . n 
C 1 67  LYS 67  141 141 LYS LYS C . n 
C 1 68  VAL 68  142 142 VAL VAL C . n 
C 1 69  LEU 69  143 143 LEU LEU C . n 
C 1 70  GLU 70  144 144 GLU GLU C . n 
C 1 71  ASP 71  145 145 ASP ASP C . n 
C 1 72  PRO 72  146 146 PRO PRO C . n 
C 1 73  ALA 73  147 147 ALA ALA C . n 
C 1 74  ILE 74  148 148 ILE ILE C . n 
C 1 75  ALA 75  149 149 ALA ALA C . n 
C 1 76  SER 76  150 150 SER SER C . n 
C 1 77  ASP 77  151 151 ASP ASP C . n 
C 1 78  GLU 78  152 152 GLU GLU C . n 
C 1 79  SER 79  153 153 SER SER C . n 
C 1 80  PHE 80  154 154 PHE PHE C . n 
C 1 81  GLY 81  155 155 GLY GLY C . n 
C 1 82  ALA 82  156 156 ALA ALA C . n 
C 1 83  VAL 83  157 157 VAL VAL C . n 
C 1 84  LYS 84  158 158 LYS LYS C . n 
C 1 85  LYS 85  159 159 LYS LYS C . n 
C 1 86  LYS 86  160 160 LYS LYS C . n 
C 1 87  PHE 87  161 161 PHE PHE C . n 
C 1 88  THR 88  162 162 THR THR C . n 
C 1 89  THR 89  163 163 THR THR C . n 
C 1 90  PHE 90  164 164 PHE PHE C . n 
C 1 91  ARG 91  165 165 ARG ARG C . n 
C 1 92  GLU 92  166 166 GLU GLU C . n 
C 1 93  ASP 93  167 167 ASP ASP C . n 
C 1 94  TYR 94  168 168 TYR TYR C . n 
C 1 95  ASP 95  169 169 ASP ASP C . n 
C 1 96  ASP 96  170 170 ASP ASP C . n 
C 1 97  ILE 97  171 171 ILE ILE C . n 
C 1 98  SER 98  172 172 SER SER C . n 
C 1 99  ASN 99  173 173 ASN ASN C . n 
C 1 100 GLN 100 174 174 GLN GLN C . n 
C 1 101 ILE 101 175 175 ILE ILE C . n 
C 1 102 ASP 102 176 176 ASP ASP C . n 
C 1 103 PHE 103 177 177 PHE PHE C . n 
C 1 104 ILE 104 178 178 ILE ILE C . n 
C 1 105 ILE 105 179 179 ILE ILE C . n 
C 1 106 CYS 106 180 180 CYS CYS C . n 
C 1 107 LEU 107 181 181 LEU LEU C . n 
C 1 108 GLY 108 182 182 GLY GLY C . n 
C 1 109 GLY 109 183 183 GLY GLY C . n 
C 1 110 ASP 110 184 184 ASP ASP C . n 
C 1 111 GLY 111 185 185 GLY GLY C . n 
C 1 112 THR 112 186 186 THR THR C . n 
C 1 113 LEU 113 187 187 LEU LEU C . n 
C 1 114 LEU 114 188 188 LEU LEU C . n 
C 1 115 TYR 115 189 189 TYR TYR C . n 
C 1 116 ALA 116 190 190 ALA ALA C . n 
C 1 117 SER 117 191 191 SER SER C . n 
C 1 118 SER 118 192 192 SER SER C . n 
C 1 119 LEU 119 193 193 LEU LEU C . n 
C 1 120 PHE 120 194 194 PHE PHE C . n 
C 1 121 GLN 121 195 195 GLN GLN C . n 
C 1 122 GLY 122 196 196 GLY GLY C . n 
C 1 123 SER 123 197 197 SER SER C . n 
C 1 124 VAL 124 198 198 VAL VAL C . n 
C 1 125 PRO 125 199 199 PRO PRO C . n 
C 1 126 PRO 126 200 200 PRO PRO C . n 
C 1 127 VAL 127 201 201 VAL VAL C . n 
C 1 128 MET 128 202 202 MET MET C . n 
C 1 129 ALA 129 203 203 ALA ALA C . n 
C 1 130 PHE 130 204 204 PHE PHE C . n 
C 1 131 HIS 131 205 205 HIS HIS C . n 
C 1 132 LEU 132 206 206 LEU LEU C . n 
C 1 133 GLY 133 207 207 GLY GLY C . n 
C 1 134 SER 134 208 208 SER SER C . n 
C 1 135 LEU 135 209 209 LEU LEU C . n 
C 1 136 GLY 136 210 210 GLY GLY C . n 
C 1 137 PHE 137 211 211 PHE PHE C . n 
C 1 138 LEU 138 212 212 LEU LEU C . n 
C 1 139 THR 139 213 213 THR THR C . n 
C 1 140 PRO 140 214 214 PRO PRO C . n 
C 1 141 PHE 141 215 215 PHE PHE C . n 
C 1 142 SER 142 216 216 SER SER C . n 
C 1 143 PHE 143 217 217 PHE PHE C . n 
C 1 144 GLU 144 218 218 GLU GLU C . n 
C 1 145 ASN 145 219 219 ASN ASN C . n 
C 1 146 PHE 146 220 220 PHE PHE C . n 
C 1 147 GLN 147 221 221 GLN GLN C . n 
C 1 148 SER 148 222 222 SER SER C . n 
C 1 149 GLN 149 223 223 GLN GLN C . n 
C 1 150 VAL 150 224 224 VAL VAL C . n 
C 1 151 THR 151 225 225 THR THR C . n 
C 1 152 GLN 152 226 226 GLN GLN C . n 
C 1 153 VAL 153 227 227 VAL VAL C . n 
C 1 154 ILE 154 228 228 ILE ILE C . n 
C 1 155 GLU 155 229 229 GLU GLU C . n 
C 1 156 GLY 156 230 230 GLY GLY C . n 
C 1 157 ASN 157 231 231 ASN ASN C . n 
C 1 158 ALA 158 232 232 ALA ALA C . n 
C 1 159 ALA 159 233 233 ALA ALA C . n 
C 1 160 VAL 160 234 234 VAL VAL C . n 
C 1 161 VAL 161 235 235 VAL VAL C . n 
C 1 162 LEU 162 236 236 LEU LEU C . n 
C 1 163 ARG 163 237 237 ARG ARG C . n 
C 1 164 SER 164 238 238 SER SER C . n 
C 1 165 ARG 165 239 239 ARG ARG C . n 
C 1 166 LEU 166 240 240 LEU LEU C . n 
C 1 167 LYS 167 241 241 LYS LYS C . n 
C 1 168 VAL 168 242 242 VAL VAL C . n 
C 1 169 ARG 169 243 243 ARG ARG C . n 
C 1 170 VAL 170 244 244 VAL VAL C . n 
C 1 171 VAL 171 245 245 VAL VAL C . n 
C 1 172 LYS 172 246 246 LYS LYS C . n 
C 1 173 GLU 173 247 247 GLU GLU C . n 
C 1 174 LEU 174 248 ?   ?   ?   C . n 
C 1 175 ARG 175 249 ?   ?   ?   C . n 
C 1 176 GLY 176 250 ?   ?   ?   C . n 
C 1 177 LYS 177 251 ?   ?   ?   C . n 
C 1 178 LYS 178 252 ?   ?   ?   C . n 
C 1 179 THR 179 253 ?   ?   ?   C . n 
C 1 180 ALA 180 254 ?   ?   ?   C . n 
C 1 181 VAL 181 255 ?   ?   ?   C . n 
C 1 182 HIS 182 256 ?   ?   ?   C . n 
C 1 183 ASN 183 257 ?   ?   ?   C . n 
C 1 184 GLY 184 258 ?   ?   ?   C . n 
C 1 185 LEU 185 259 ?   ?   ?   C . n 
C 1 186 GLY 186 260 ?   ?   ?   C . n 
C 1 187 GLU 187 261 ?   ?   ?   C . n 
C 1 188 ASN 188 262 ?   ?   ?   C . n 
C 1 189 GLY 189 263 ?   ?   ?   C . n 
C 1 190 SER 190 264 ?   ?   ?   C . n 
C 1 191 GLN 191 265 ?   ?   ?   C . n 
C 1 192 ALA 192 266 ?   ?   ?   C . n 
C 1 193 ALA 193 267 ?   ?   ?   C . n 
C 1 194 GLY 194 268 ?   ?   ?   C . n 
C 1 195 LEU 195 269 ?   ?   ?   C . n 
C 1 196 ASP 196 270 ?   ?   ?   C . n 
C 1 197 MET 197 271 ?   ?   ?   C . n 
C 1 198 ASP 198 272 ?   ?   ?   C . n 
C 1 199 VAL 199 273 ?   ?   ?   C . n 
C 1 200 GLY 200 274 ?   ?   ?   C . n 
C 1 201 LYS 201 275 ?   ?   ?   C . n 
C 1 202 GLN 202 276 ?   ?   ?   C . n 
C 1 203 ALA 203 277 277 ALA ALA C . n 
C 1 204 MET 204 278 278 MET MET C . n 
C 1 205 GLN 205 279 279 GLN GLN C . n 
C 1 206 TYR 206 280 280 TYR TYR C . n 
C 1 207 GLN 207 281 281 GLN GLN C . n 
C 1 208 VAL 208 282 282 VAL VAL C . n 
C 1 209 LEU 209 283 283 LEU LEU C . n 
C 1 210 ASN 210 284 284 ASN ASN C . n 
C 1 211 GLU 211 285 285 GLU GLU C . n 
C 1 212 VAL 212 286 286 VAL VAL C . n 
C 1 213 VAL 213 287 287 VAL VAL C . n 
C 1 214 ILE 214 288 288 ILE ILE C . n 
C 1 215 ASP 215 289 289 ASP ASP C . n 
C 1 216 ARG 216 290 290 ARG ARG C . n 
C 1 217 GLY 217 291 291 GLY GLY C . n 
C 1 218 PRO 218 292 292 PRO PRO C . n 
C 1 219 SER 219 293 293 SER SER C . n 
C 1 220 SER 220 294 294 SER SER C . n 
C 1 221 TYR 221 295 295 TYR TYR C . n 
C 1 222 LEU 222 296 296 LEU LEU C . n 
C 1 223 SER 223 297 297 SER SER C . n 
C 1 224 ASN 224 298 298 ASN ASN C . n 
C 1 225 VAL 225 299 299 VAL VAL C . n 
C 1 226 ASP 226 300 300 ASP ASP C . n 
C 1 227 VAL 227 301 301 VAL VAL C . n 
C 1 228 TYR 228 302 302 TYR TYR C . n 
C 1 229 LEU 229 303 303 LEU LEU C . n 
C 1 230 ASP 230 304 304 ASP ASP C . n 
C 1 231 GLY 231 305 305 GLY GLY C . n 
C 1 232 HIS 232 306 306 HIS HIS C . n 
C 1 233 LEU 233 307 307 LEU LEU C . n 
C 1 234 ILE 234 308 308 ILE ILE C . n 
C 1 235 THR 235 309 309 THR THR C . n 
C 1 236 THR 236 310 310 THR THR C . n 
C 1 237 VAL 237 311 311 VAL VAL C . n 
C 1 238 GLN 238 312 312 GLN GLN C . n 
C 1 239 GLY 239 313 313 GLY GLY C . n 
C 1 240 ASP 240 314 314 ASP ASP C . n 
C 1 241 GLY 241 315 315 GLY GLY C . n 
C 1 242 VAL 242 316 316 VAL VAL C . n 
C 1 243 ILE 243 317 317 ILE ILE C . n 
C 1 244 VAL 244 318 318 VAL VAL C . n 
C 1 245 SER 245 319 319 SER SER C . n 
C 1 246 THR 246 320 320 THR THR C . n 
C 1 247 PRO 247 321 321 PRO PRO C . n 
C 1 248 THR 248 322 322 THR THR C . n 
C 1 249 GLY 249 323 323 GLY GLY C . n 
C 1 250 SER 250 324 324 SER SER C . n 
C 1 251 THR 251 325 325 THR THR C . n 
C 1 252 ALA 252 326 326 ALA ALA C . n 
C 1 253 TYR 253 327 327 TYR TYR C . n 
C 1 254 ALA 254 328 328 ALA ALA C . n 
C 1 255 ALA 255 329 329 ALA ALA C . n 
C 1 256 ALA 256 330 330 ALA ALA C . n 
C 1 257 ALA 257 331 331 ALA ALA C . n 
C 1 258 GLY 258 332 332 GLY GLY C . n 
C 1 259 ALA 259 333 333 ALA ALA C . n 
C 1 260 SER 260 334 334 SER SER C . n 
C 1 261 MET 261 335 335 MET MET C . n 
C 1 262 ILE 262 336 336 ILE ILE C . n 
C 1 263 HIS 263 337 337 HIS HIS C . n 
C 1 264 PRO 264 338 338 PRO PRO C . n 
C 1 265 ASN 265 339 339 ASN ASN C . n 
C 1 266 VAL 266 340 340 VAL VAL C . n 
C 1 267 PRO 267 341 341 PRO PRO C . n 
C 1 268 ALA 268 342 342 ALA ALA C . n 
C 1 269 ILE 269 343 343 ILE ILE C . n 
C 1 270 MET 270 344 344 MET MET C . n 
C 1 271 ILE 271 345 345 ILE ILE C . n 
C 1 272 THR 272 346 346 THR THR C . n 
C 1 273 PRO 273 347 347 PRO PRO C . n 
C 1 274 ILE 274 348 348 ILE ILE C . n 
C 1 275 CYS 275 349 349 CYS CYS C . n 
C 1 276 PRO 276 350 350 PRO PRO C . n 
C 1 277 HIS 277 351 351 HIS HIS C . n 
C 1 278 SER 278 352 352 SER SER C . n 
C 1 279 LEU 279 353 353 LEU LEU C . n 
C 1 280 SER 280 354 354 SER SER C . n 
C 1 281 PHE 281 355 355 PHE PHE C . n 
C 1 282 ARG 282 356 356 ARG ARG C . n 
C 1 283 PRO 283 357 357 PRO PRO C . n 
C 1 284 ILE 284 358 358 ILE ILE C . n 
C 1 285 VAL 285 359 359 VAL VAL C . n 
C 1 286 VAL 286 360 360 VAL VAL C . n 
C 1 287 PRO 287 361 361 PRO PRO C . n 
C 1 288 ALA 288 362 362 ALA ALA C . n 
C 1 289 GLY 289 363 363 GLY GLY C . n 
C 1 290 VAL 290 364 364 VAL VAL C . n 
C 1 291 GLU 291 365 365 GLU GLU C . n 
C 1 292 LEU 292 366 366 LEU LEU C . n 
C 1 293 LYS 293 367 367 LYS LYS C . n 
C 1 294 ILE 294 368 368 ILE ILE C . n 
C 1 295 MET 295 369 369 MET MET C . n 
C 1 296 LEU 296 370 370 LEU LEU C . n 
C 1 297 SER 297 371 371 SER SER C . n 
C 1 298 PRO 298 372 372 PRO PRO C . n 
C 1 299 GLU 299 373 373 GLU GLU C . n 
C 1 300 ALA 300 374 374 ALA ALA C . n 
C 1 301 ARG 301 375 375 ARG ARG C . n 
C 1 302 ASN 302 376 376 ASN ASN C . n 
C 1 303 THR 303 377 377 THR THR C . n 
C 1 304 ALA 304 378 378 ALA ALA C . n 
C 1 305 TRP 305 379 379 TRP TRP C . n 
C 1 306 VAL 306 380 380 VAL VAL C . n 
C 1 307 SER 307 381 381 SER SER C . n 
C 1 308 PHE 308 382 382 PHE PHE C . n 
C 1 309 ASP 309 383 383 ASP ASP C . n 
C 1 310 GLY 310 384 384 GLY GLY C . n 
C 1 311 ARG 311 385 385 ARG ARG C . n 
C 1 312 LYS 312 386 386 LYS LYS C . n 
C 1 313 ARG 313 387 387 ARG ARG C . n 
C 1 314 GLN 314 388 388 GLN GLN C . n 
C 1 315 GLU 315 389 389 GLU GLU C . n 
C 1 316 ILE 316 390 390 ILE ILE C . n 
C 1 317 ARG 317 391 391 ARG ARG C . n 
C 1 318 HIS 318 392 392 HIS HIS C . n 
C 1 319 GLY 319 393 393 GLY GLY C . n 
C 1 320 ASP 320 394 394 ASP ASP C . n 
C 1 321 SER 321 395 395 SER SER C . n 
C 1 322 ILE 322 396 396 ILE ILE C . n 
C 1 323 SER 323 397 397 SER SER C . n 
C 1 324 ILE 324 398 398 ILE ILE C . n 
C 1 325 THR 325 399 399 THR THR C . n 
C 1 326 THR 326 400 400 THR THR C . n 
C 1 327 SER 327 401 401 SER SER C . n 
C 1 328 THR 328 402 402 THR THR C . n 
C 1 329 TYR 329 403 403 TYR TYR C . n 
C 1 330 PRO 330 404 404 PRO PRO C . n 
C 1 331 LEU 331 405 405 LEU LEU C . n 
C 1 332 PRO 332 406 406 PRO PRO C . n 
C 1 333 SER 333 407 407 SER SER C . n 
C 1 334 ILE 334 408 408 ILE ILE C . n 
C 1 335 CYS 335 409 409 CYS CYS C . n 
C 1 336 VAL 336 410 410 VAL VAL C . n 
C 1 337 ARG 337 411 411 ARG ARG C . n 
C 1 338 ASP 338 412 412 ASP ASP C . n 
C 1 339 PRO 339 413 413 PRO PRO C . n 
C 1 340 VAL 340 414 414 VAL VAL C . n 
C 1 341 SER 341 415 415 SER SER C . n 
C 1 342 ASP 342 416 416 ASP ASP C . n 
C 1 343 TRP 343 417 417 TRP TRP C . n 
C 1 344 PHE 344 418 418 PHE PHE C . n 
C 1 345 GLU 345 419 419 GLU GLU C . n 
C 1 346 SER 346 420 420 SER SER C . n 
C 1 347 LEU 347 421 421 LEU LEU C . n 
C 1 348 ALA 348 422 422 ALA ALA C . n 
C 1 349 GLN 349 423 423 GLN GLN C . n 
C 1 350 CYS 350 424 424 CYS CYS C . n 
C 1 351 LEU 351 425 425 LEU LEU C . n 
C 1 352 HIS 352 426 426 HIS HIS C . n 
C 1 353 TRP 353 427 427 TRP TRP C . n 
C 1 354 ASN 354 428 428 ASN ASN C . n 
C 1 355 VAL 355 429 429 VAL VAL C . n 
C 1 356 ARG 356 430 430 ARG ARG C . n 
C 1 357 LYS 357 431 ?   ?   ?   C . n 
C 1 358 LYS 358 432 ?   ?   ?   C . n 
C 1 359 GLN 359 433 ?   ?   ?   C . n 
C 1 360 ALA 360 434 ?   ?   ?   C . n 
C 1 361 HIS 361 435 ?   ?   ?   C . n 
C 1 362 PHE 362 436 ?   ?   ?   C . n 
C 1 363 GLU 363 437 ?   ?   ?   C . n 
C 1 364 LEU 364 438 ?   ?   ?   C . n 
C 1 365 GLY 365 439 ?   ?   ?   C . n 
C 1 366 LEU 366 440 ?   ?   ?   C . n 
C 1 367 GLU 367 441 ?   ?   ?   C . n 
C 1 368 HIS 368 442 ?   ?   ?   C . n 
C 1 369 HIS 369 443 ?   ?   ?   C . n 
C 1 370 HIS 370 444 ?   ?   ?   C . n 
C 1 371 HIS 371 445 ?   ?   ?   C . n 
C 1 372 HIS 372 446 ?   ?   ?   C . n 
C 1 373 HIS 373 447 ?   ?   ?   C . n 
D 1 1   MET 1   67  ?   ?   ?   D . n 
D 1 2   PRO 2   68  ?   ?   ?   D . n 
D 1 3   SER 3   69  ?   ?   ?   D . n 
D 1 4   PRO 4   70  ?   ?   ?   D . n 
D 1 5   VAL 5   71  ?   ?   ?   D . n 
D 1 6   THR 6   72  ?   ?   ?   D . n 
D 1 7   THR 7   73  73  THR THR D . n 
D 1 8   PHE 8   74  74  PHE PHE D . n 
D 1 9   GLY 9   75  75  GLY GLY D . n 
D 1 10  PRO 10  76  76  PRO PRO D . n 
D 1 11  LYS 11  77  77  LYS LYS D . n 
D 1 12  ALA 12  78  78  ALA ALA D . n 
D 1 13  THR 13  79  79  THR THR D . n 
D 1 14  VAL 14  80  80  VAL VAL D . n 
D 1 15  GLU 15  89  ?   ?   ?   D . n 
D 1 16  THR 16  90  ?   ?   ?   D . n 
D 1 17  GLN 17  91  ?   ?   ?   D . n 
D 1 18  ASP 18  92  ?   ?   ?   D . n 
D 1 19  PRO 19  93  ?   ?   ?   D . n 
D 1 20  ALA 20  94  ?   ?   ?   D . n 
D 1 21  SER 21  95  ?   ?   ?   D . n 
D 1 22  VAL 22  96  96  VAL VAL D . n 
D 1 23  ARG 23  97  97  ARG ARG D . n 
D 1 24  LEU 24  98  98  LEU LEU D . n 
D 1 25  THR 25  99  99  THR THR D . n 
D 1 26  TRP 26  100 100 TRP TRP D . n 
D 1 27  ASN 27  101 101 ASN ASN D . n 
D 1 28  LYS 28  102 102 LYS LYS D . n 
D 1 29  SER 29  103 103 SER SER D . n 
D 1 30  PRO 30  104 104 PRO PRO D . n 
D 1 31  LYS 31  105 105 LYS LYS D . n 
D 1 32  SER 32  106 106 SER SER D . n 
D 1 33  VAL 33  107 107 VAL VAL D . n 
D 1 34  LEU 34  108 108 LEU LEU D . n 
D 1 35  VAL 35  109 109 VAL VAL D . n 
D 1 36  ILE 36  110 110 ILE ILE D . n 
D 1 37  LYS 37  111 111 LYS LYS D . n 
D 1 38  LYS 38  112 112 LYS LYS D . n 
D 1 39  MET 39  113 113 MET MET D . n 
D 1 40  ARG 40  114 114 ARG ARG D . n 
D 1 41  ASP 41  115 115 ASP ASP D . n 
D 1 42  ALA 42  116 116 ALA ALA D . n 
D 1 43  SER 43  117 117 SER SER D . n 
D 1 44  LEU 44  118 118 LEU LEU D . n 
D 1 45  LEU 45  119 119 LEU LEU D . n 
D 1 46  GLN 46  120 120 GLN GLN D . n 
D 1 47  PRO 47  121 121 PRO PRO D . n 
D 1 48  PHE 48  122 122 PHE PHE D . n 
D 1 49  LYS 49  123 123 LYS LYS D . n 
D 1 50  GLU 50  124 124 GLU GLU D . n 
D 1 51  LEU 51  125 125 LEU LEU D . n 
D 1 52  CYS 52  126 126 CYS CYS D . n 
D 1 53  THR 53  127 127 THR THR D . n 
D 1 54  HIS 54  128 128 HIS HIS D . n 
D 1 55  LEU 55  129 129 LEU LEU D . n 
D 1 56  MET 56  130 130 MET MET D . n 
D 1 57  GLU 57  131 131 GLU GLU D . n 
D 1 58  GLU 58  132 132 GLU GLU D . n 
D 1 59  ASN 59  133 133 ASN ASN D . n 
D 1 60  MET 60  134 134 MET MET D . n 
D 1 61  ILE 61  135 135 ILE ILE D . n 
D 1 62  VAL 62  136 136 VAL VAL D . n 
D 1 63  TYR 63  137 137 TYR TYR D . n 
D 1 64  VAL 64  138 138 VAL VAL D . n 
D 1 65  GLU 65  139 139 GLU GLU D . n 
D 1 66  LYS 66  140 140 LYS LYS D . n 
D 1 67  LYS 67  141 141 LYS LYS D . n 
D 1 68  VAL 68  142 142 VAL VAL D . n 
D 1 69  LEU 69  143 143 LEU LEU D . n 
D 1 70  GLU 70  144 144 GLU GLU D . n 
D 1 71  ASP 71  145 145 ASP ASP D . n 
D 1 72  PRO 72  146 146 PRO PRO D . n 
D 1 73  ALA 73  147 147 ALA ALA D . n 
D 1 74  ILE 74  148 148 ILE ILE D . n 
D 1 75  ALA 75  149 149 ALA ALA D . n 
D 1 76  SER 76  150 150 SER SER D . n 
D 1 77  ASP 77  151 151 ASP ASP D . n 
D 1 78  GLU 78  152 152 GLU GLU D . n 
D 1 79  SER 79  153 153 SER SER D . n 
D 1 80  PHE 80  154 154 PHE PHE D . n 
D 1 81  GLY 81  155 155 GLY GLY D . n 
D 1 82  ALA 82  156 156 ALA ALA D . n 
D 1 83  VAL 83  157 157 VAL VAL D . n 
D 1 84  LYS 84  158 158 LYS LYS D . n 
D 1 85  LYS 85  159 159 LYS LYS D . n 
D 1 86  LYS 86  160 160 LYS LYS D . n 
D 1 87  PHE 87  161 161 PHE PHE D . n 
D 1 88  THR 88  162 162 THR THR D . n 
D 1 89  THR 89  163 163 THR THR D . n 
D 1 90  PHE 90  164 164 PHE PHE D . n 
D 1 91  ARG 91  165 165 ARG ARG D . n 
D 1 92  GLU 92  166 166 GLU GLU D . n 
D 1 93  ASP 93  167 167 ASP ASP D . n 
D 1 94  TYR 94  168 168 TYR TYR D . n 
D 1 95  ASP 95  169 169 ASP ASP D . n 
D 1 96  ASP 96  170 170 ASP ASP D . n 
D 1 97  ILE 97  171 171 ILE ILE D . n 
D 1 98  SER 98  172 172 SER SER D . n 
D 1 99  ASN 99  173 173 ASN ASN D . n 
D 1 100 GLN 100 174 174 GLN GLN D . n 
D 1 101 ILE 101 175 175 ILE ILE D . n 
D 1 102 ASP 102 176 176 ASP ASP D . n 
D 1 103 PHE 103 177 177 PHE PHE D . n 
D 1 104 ILE 104 178 178 ILE ILE D . n 
D 1 105 ILE 105 179 179 ILE ILE D . n 
D 1 106 CYS 106 180 180 CYS CYS D . n 
D 1 107 LEU 107 181 181 LEU LEU D . n 
D 1 108 GLY 108 182 182 GLY GLY D . n 
D 1 109 GLY 109 183 183 GLY GLY D . n 
D 1 110 ASP 110 184 184 ASP ASP D . n 
D 1 111 GLY 111 185 185 GLY GLY D . n 
D 1 112 THR 112 186 186 THR THR D . n 
D 1 113 LEU 113 187 187 LEU LEU D . n 
D 1 114 LEU 114 188 188 LEU LEU D . n 
D 1 115 TYR 115 189 189 TYR TYR D . n 
D 1 116 ALA 116 190 190 ALA ALA D . n 
D 1 117 SER 117 191 191 SER SER D . n 
D 1 118 SER 118 192 192 SER SER D . n 
D 1 119 LEU 119 193 193 LEU LEU D . n 
D 1 120 PHE 120 194 194 PHE PHE D . n 
D 1 121 GLN 121 195 195 GLN GLN D . n 
D 1 122 GLY 122 196 196 GLY GLY D . n 
D 1 123 SER 123 197 197 SER SER D . n 
D 1 124 VAL 124 198 198 VAL VAL D . n 
D 1 125 PRO 125 199 199 PRO PRO D . n 
D 1 126 PRO 126 200 200 PRO PRO D . n 
D 1 127 VAL 127 201 201 VAL VAL D . n 
D 1 128 MET 128 202 202 MET MET D . n 
D 1 129 ALA 129 203 203 ALA ALA D . n 
D 1 130 PHE 130 204 204 PHE PHE D . n 
D 1 131 HIS 131 205 205 HIS HIS D . n 
D 1 132 LEU 132 206 206 LEU LEU D . n 
D 1 133 GLY 133 207 207 GLY GLY D . n 
D 1 134 SER 134 208 208 SER SER D . n 
D 1 135 LEU 135 209 209 LEU LEU D . n 
D 1 136 GLY 136 210 210 GLY GLY D . n 
D 1 137 PHE 137 211 211 PHE PHE D . n 
D 1 138 LEU 138 212 212 LEU LEU D . n 
D 1 139 THR 139 213 213 THR THR D . n 
D 1 140 PRO 140 214 214 PRO PRO D . n 
D 1 141 PHE 141 215 215 PHE PHE D . n 
D 1 142 SER 142 216 216 SER SER D . n 
D 1 143 PHE 143 217 217 PHE PHE D . n 
D 1 144 GLU 144 218 218 GLU GLU D . n 
D 1 145 ASN 145 219 219 ASN ASN D . n 
D 1 146 PHE 146 220 220 PHE PHE D . n 
D 1 147 GLN 147 221 221 GLN GLN D . n 
D 1 148 SER 148 222 222 SER SER D . n 
D 1 149 GLN 149 223 223 GLN GLN D . n 
D 1 150 VAL 150 224 224 VAL VAL D . n 
D 1 151 THR 151 225 225 THR THR D . n 
D 1 152 GLN 152 226 226 GLN GLN D . n 
D 1 153 VAL 153 227 227 VAL VAL D . n 
D 1 154 ILE 154 228 228 ILE ILE D . n 
D 1 155 GLU 155 229 229 GLU GLU D . n 
D 1 156 GLY 156 230 230 GLY GLY D . n 
D 1 157 ASN 157 231 231 ASN ASN D . n 
D 1 158 ALA 158 232 232 ALA ALA D . n 
D 1 159 ALA 159 233 233 ALA ALA D . n 
D 1 160 VAL 160 234 234 VAL VAL D . n 
D 1 161 VAL 161 235 235 VAL VAL D . n 
D 1 162 LEU 162 236 236 LEU LEU D . n 
D 1 163 ARG 163 237 237 ARG ARG D . n 
D 1 164 SER 164 238 238 SER SER D . n 
D 1 165 ARG 165 239 239 ARG ARG D . n 
D 1 166 LEU 166 240 240 LEU LEU D . n 
D 1 167 LYS 167 241 241 LYS LYS D . n 
D 1 168 VAL 168 242 242 VAL VAL D . n 
D 1 169 ARG 169 243 243 ARG ARG D . n 
D 1 170 VAL 170 244 244 VAL VAL D . n 
D 1 171 VAL 171 245 245 VAL VAL D . n 
D 1 172 LYS 172 246 246 LYS LYS D . n 
D 1 173 GLU 173 247 247 GLU GLU D . n 
D 1 174 LEU 174 248 ?   ?   ?   D . n 
D 1 175 ARG 175 249 ?   ?   ?   D . n 
D 1 176 GLY 176 250 ?   ?   ?   D . n 
D 1 177 LYS 177 251 ?   ?   ?   D . n 
D 1 178 LYS 178 252 ?   ?   ?   D . n 
D 1 179 THR 179 253 ?   ?   ?   D . n 
D 1 180 ALA 180 254 ?   ?   ?   D . n 
D 1 181 VAL 181 255 ?   ?   ?   D . n 
D 1 182 HIS 182 256 ?   ?   ?   D . n 
D 1 183 ASN 183 257 ?   ?   ?   D . n 
D 1 184 GLY 184 258 ?   ?   ?   D . n 
D 1 185 LEU 185 259 ?   ?   ?   D . n 
D 1 186 GLY 186 260 ?   ?   ?   D . n 
D 1 187 GLU 187 261 ?   ?   ?   D . n 
D 1 188 ASN 188 262 ?   ?   ?   D . n 
D 1 189 GLY 189 263 ?   ?   ?   D . n 
D 1 190 SER 190 264 ?   ?   ?   D . n 
D 1 191 GLN 191 265 ?   ?   ?   D . n 
D 1 192 ALA 192 266 ?   ?   ?   D . n 
D 1 193 ALA 193 267 ?   ?   ?   D . n 
D 1 194 GLY 194 268 ?   ?   ?   D . n 
D 1 195 LEU 195 269 ?   ?   ?   D . n 
D 1 196 ASP 196 270 ?   ?   ?   D . n 
D 1 197 MET 197 271 ?   ?   ?   D . n 
D 1 198 ASP 198 272 ?   ?   ?   D . n 
D 1 199 VAL 199 273 ?   ?   ?   D . n 
D 1 200 GLY 200 274 ?   ?   ?   D . n 
D 1 201 LYS 201 275 ?   ?   ?   D . n 
D 1 202 GLN 202 276 ?   ?   ?   D . n 
D 1 203 ALA 203 277 277 ALA ALA D . n 
D 1 204 MET 204 278 278 MET MET D . n 
D 1 205 GLN 205 279 279 GLN GLN D . n 
D 1 206 TYR 206 280 280 TYR TYR D . n 
D 1 207 GLN 207 281 281 GLN GLN D . n 
D 1 208 VAL 208 282 282 VAL VAL D . n 
D 1 209 LEU 209 283 283 LEU LEU D . n 
D 1 210 ASN 210 284 284 ASN ASN D . n 
D 1 211 GLU 211 285 285 GLU GLU D . n 
D 1 212 VAL 212 286 286 VAL VAL D . n 
D 1 213 VAL 213 287 287 VAL VAL D . n 
D 1 214 ILE 214 288 288 ILE ILE D . n 
D 1 215 ASP 215 289 289 ASP ASP D . n 
D 1 216 ARG 216 290 290 ARG ARG D . n 
D 1 217 GLY 217 291 291 GLY GLY D . n 
D 1 218 PRO 218 292 292 PRO PRO D . n 
D 1 219 SER 219 293 293 SER SER D . n 
D 1 220 SER 220 294 294 SER SER D . n 
D 1 221 TYR 221 295 295 TYR TYR D . n 
D 1 222 LEU 222 296 296 LEU LEU D . n 
D 1 223 SER 223 297 297 SER SER D . n 
D 1 224 ASN 224 298 298 ASN ASN D . n 
D 1 225 VAL 225 299 299 VAL VAL D . n 
D 1 226 ASP 226 300 300 ASP ASP D . n 
D 1 227 VAL 227 301 301 VAL VAL D . n 
D 1 228 TYR 228 302 302 TYR TYR D . n 
D 1 229 LEU 229 303 303 LEU LEU D . n 
D 1 230 ASP 230 304 304 ASP ASP D . n 
D 1 231 GLY 231 305 305 GLY GLY D . n 
D 1 232 HIS 232 306 306 HIS HIS D . n 
D 1 233 LEU 233 307 307 LEU LEU D . n 
D 1 234 ILE 234 308 308 ILE ILE D . n 
D 1 235 THR 235 309 309 THR THR D . n 
D 1 236 THR 236 310 310 THR THR D . n 
D 1 237 VAL 237 311 311 VAL VAL D . n 
D 1 238 GLN 238 312 312 GLN GLN D . n 
D 1 239 GLY 239 313 313 GLY GLY D . n 
D 1 240 ASP 240 314 314 ASP ASP D . n 
D 1 241 GLY 241 315 315 GLY GLY D . n 
D 1 242 VAL 242 316 316 VAL VAL D . n 
D 1 243 ILE 243 317 317 ILE ILE D . n 
D 1 244 VAL 244 318 318 VAL VAL D . n 
D 1 245 SER 245 319 319 SER SER D . n 
D 1 246 THR 246 320 320 THR THR D . n 
D 1 247 PRO 247 321 321 PRO PRO D . n 
D 1 248 THR 248 322 322 THR THR D . n 
D 1 249 GLY 249 323 323 GLY GLY D . n 
D 1 250 SER 250 324 324 SER SER D . n 
D 1 251 THR 251 325 325 THR THR D . n 
D 1 252 ALA 252 326 326 ALA ALA D . n 
D 1 253 TYR 253 327 327 TYR TYR D . n 
D 1 254 ALA 254 328 328 ALA ALA D . n 
D 1 255 ALA 255 329 329 ALA ALA D . n 
D 1 256 ALA 256 330 330 ALA ALA D . n 
D 1 257 ALA 257 331 331 ALA ALA D . n 
D 1 258 GLY 258 332 332 GLY GLY D . n 
D 1 259 ALA 259 333 333 ALA ALA D . n 
D 1 260 SER 260 334 334 SER SER D . n 
D 1 261 MET 261 335 335 MET MET D . n 
D 1 262 ILE 262 336 336 ILE ILE D . n 
D 1 263 HIS 263 337 337 HIS HIS D . n 
D 1 264 PRO 264 338 338 PRO PRO D . n 
D 1 265 ASN 265 339 339 ASN ASN D . n 
D 1 266 VAL 266 340 340 VAL VAL D . n 
D 1 267 PRO 267 341 341 PRO PRO D . n 
D 1 268 ALA 268 342 342 ALA ALA D . n 
D 1 269 ILE 269 343 343 ILE ILE D . n 
D 1 270 MET 270 344 344 MET MET D . n 
D 1 271 ILE 271 345 345 ILE ILE D . n 
D 1 272 THR 272 346 346 THR THR D . n 
D 1 273 PRO 273 347 347 PRO PRO D . n 
D 1 274 ILE 274 348 348 ILE ILE D . n 
D 1 275 CYS 275 349 349 CYS CYS D . n 
D 1 276 PRO 276 350 350 PRO PRO D . n 
D 1 277 HIS 277 351 351 HIS HIS D . n 
D 1 278 SER 278 352 352 SER SER D . n 
D 1 279 LEU 279 353 353 LEU LEU D . n 
D 1 280 SER 280 354 354 SER SER D . n 
D 1 281 PHE 281 355 355 PHE PHE D . n 
D 1 282 ARG 282 356 356 ARG ARG D . n 
D 1 283 PRO 283 357 357 PRO PRO D . n 
D 1 284 ILE 284 358 358 ILE ILE D . n 
D 1 285 VAL 285 359 359 VAL VAL D . n 
D 1 286 VAL 286 360 360 VAL VAL D . n 
D 1 287 PRO 287 361 361 PRO PRO D . n 
D 1 288 ALA 288 362 362 ALA ALA D . n 
D 1 289 GLY 289 363 363 GLY GLY D . n 
D 1 290 VAL 290 364 364 VAL VAL D . n 
D 1 291 GLU 291 365 365 GLU GLU D . n 
D 1 292 LEU 292 366 366 LEU LEU D . n 
D 1 293 LYS 293 367 367 LYS LYS D . n 
D 1 294 ILE 294 368 368 ILE ILE D . n 
D 1 295 MET 295 369 369 MET MET D . n 
D 1 296 LEU 296 370 370 LEU LEU D . n 
D 1 297 SER 297 371 371 SER SER D . n 
D 1 298 PRO 298 372 372 PRO PRO D . n 
D 1 299 GLU 299 373 373 GLU GLU D . n 
D 1 300 ALA 300 374 374 ALA ALA D . n 
D 1 301 ARG 301 375 375 ARG ARG D . n 
D 1 302 ASN 302 376 376 ASN ASN D . n 
D 1 303 THR 303 377 377 THR THR D . n 
D 1 304 ALA 304 378 378 ALA ALA D . n 
D 1 305 TRP 305 379 379 TRP TRP D . n 
D 1 306 VAL 306 380 380 VAL VAL D . n 
D 1 307 SER 307 381 381 SER SER D . n 
D 1 308 PHE 308 382 382 PHE PHE D . n 
D 1 309 ASP 309 383 383 ASP ASP D . n 
D 1 310 GLY 310 384 384 GLY GLY D . n 
D 1 311 ARG 311 385 385 ARG ARG D . n 
D 1 312 LYS 312 386 386 LYS LYS D . n 
D 1 313 ARG 313 387 387 ARG ARG D . n 
D 1 314 GLN 314 388 388 GLN GLN D . n 
D 1 315 GLU 315 389 389 GLU GLU D . n 
D 1 316 ILE 316 390 390 ILE ILE D . n 
D 1 317 ARG 317 391 391 ARG ARG D . n 
D 1 318 HIS 318 392 392 HIS HIS D . n 
D 1 319 GLY 319 393 393 GLY GLY D . n 
D 1 320 ASP 320 394 394 ASP ASP D . n 
D 1 321 SER 321 395 395 SER SER D . n 
D 1 322 ILE 322 396 396 ILE ILE D . n 
D 1 323 SER 323 397 397 SER SER D . n 
D 1 324 ILE 324 398 398 ILE ILE D . n 
D 1 325 THR 325 399 399 THR THR D . n 
D 1 326 THR 326 400 400 THR THR D . n 
D 1 327 SER 327 401 401 SER SER D . n 
D 1 328 THR 328 402 402 THR THR D . n 
D 1 329 TYR 329 403 403 TYR TYR D . n 
D 1 330 PRO 330 404 404 PRO PRO D . n 
D 1 331 LEU 331 405 405 LEU LEU D . n 
D 1 332 PRO 332 406 406 PRO PRO D . n 
D 1 333 SER 333 407 407 SER SER D . n 
D 1 334 ILE 334 408 408 ILE ILE D . n 
D 1 335 CYS 335 409 409 CYS CYS D . n 
D 1 336 VAL 336 410 410 VAL VAL D . n 
D 1 337 ARG 337 411 411 ARG ARG D . n 
D 1 338 ASP 338 412 412 ASP ASP D . n 
D 1 339 PRO 339 413 413 PRO PRO D . n 
D 1 340 VAL 340 414 414 VAL VAL D . n 
D 1 341 SER 341 415 415 SER SER D . n 
D 1 342 ASP 342 416 416 ASP ASP D . n 
D 1 343 TRP 343 417 417 TRP TRP D . n 
D 1 344 PHE 344 418 418 PHE PHE D . n 
D 1 345 GLU 345 419 419 GLU GLU D . n 
D 1 346 SER 346 420 420 SER SER D . n 
D 1 347 LEU 347 421 421 LEU LEU D . n 
D 1 348 ALA 348 422 422 ALA ALA D . n 
D 1 349 GLN 349 423 423 GLN GLN D . n 
D 1 350 CYS 350 424 424 CYS CYS D . n 
D 1 351 LEU 351 425 425 LEU LEU D . n 
D 1 352 HIS 352 426 426 HIS HIS D . n 
D 1 353 TRP 353 427 427 TRP TRP D . n 
D 1 354 ASN 354 428 428 ASN ASN D . n 
D 1 355 VAL 355 429 429 VAL VAL D . n 
D 1 356 ARG 356 430 430 ARG ARG D . n 
D 1 357 LYS 357 431 ?   ?   ?   D . n 
D 1 358 LYS 358 432 ?   ?   ?   D . n 
D 1 359 GLN 359 433 ?   ?   ?   D . n 
D 1 360 ALA 360 434 ?   ?   ?   D . n 
D 1 361 HIS 361 435 ?   ?   ?   D . n 
D 1 362 PHE 362 436 ?   ?   ?   D . n 
D 1 363 GLU 363 437 ?   ?   ?   D . n 
D 1 364 LEU 364 438 ?   ?   ?   D . n 
D 1 365 GLY 365 439 ?   ?   ?   D . n 
D 1 366 LEU 366 440 ?   ?   ?   D . n 
D 1 367 GLU 367 441 ?   ?   ?   D . n 
D 1 368 HIS 368 442 ?   ?   ?   D . n 
D 1 369 HIS 369 443 ?   ?   ?   D . n 
D 1 370 HIS 370 444 ?   ?   ?   D . n 
D 1 371 HIS 371 445 ?   ?   ?   D . n 
D 1 372 HIS 372 446 ?   ?   ?   D . n 
D 1 373 HIS 373 447 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NAD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NAD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 NAD 1 501 501 NAD NAD A . 
F 2 NAD 1 501 501 NAD NAD B . 
G 2 NAD 1 501 501 NAD NAD C . 
H 2 NAD 1 501 501 NAD NAD D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B GLN 276 ? CG  ? B GLN 202 CG  
2 1 Y 1 B GLN 276 ? CD  ? B GLN 202 CD  
3 1 Y 1 B GLN 276 ? OE1 ? B GLN 202 OE1 
4 1 Y 1 B GLN 276 ? NE2 ? B GLN 202 NE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CRA 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CRA 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CRA 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9CRA 
_struct.title                        'CryoEM Structure of the C-terminally truncated form of human NAD Kinase bound to NAD' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CRA 
_struct_keywords.text            'catalyzes the reaction of ATP + NAD+ = ADP + H+ + NADP+, SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    NADK_HUMAN 
_struct_ref.pdbx_db_accession          O95544 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QDPASQRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESFGAVKKKFCTFREDYDD
ISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRG
KKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAA
AGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICV
RDPVSDWFESLAQCLHWNVRKKQAHFE
;
_struct_ref.pdbx_align_begin           91 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CRA A 17 ? 363 ? O95544 91 ? 437 ? 91 437 
2 1 9CRA B 17 ? 363 ? O95544 91 ? 437 ? 91 437 
3 1 9CRA C 17 ? 363 ? O95544 91 ? 437 ? 91 437 
4 1 9CRA D 17 ? 363 ? O95544 91 ? 437 ? 91 437 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CRA MET A 1   ? UNP O95544 ?   ?   'initiating methionine' 67  1   
1 9CRA PRO A 2   ? UNP O95544 ?   ?   'expression tag'        68  2   
1 9CRA SER A 3   ? UNP O95544 ?   ?   'expression tag'        69  3   
1 9CRA PRO A 4   ? UNP O95544 ?   ?   'expression tag'        70  4   
1 9CRA VAL A 5   ? UNP O95544 ?   ?   'expression tag'        71  5   
1 9CRA THR A 6   ? UNP O95544 ?   ?   'expression tag'        72  6   
1 9CRA THR A 7   ? UNP O95544 ?   ?   'expression tag'        73  7   
1 9CRA PHE A 8   ? UNP O95544 ?   ?   'expression tag'        74  8   
1 9CRA GLY A 9   ? UNP O95544 ?   ?   'expression tag'        75  9   
1 9CRA PRO A 10  ? UNP O95544 ?   ?   'expression tag'        76  10  
1 9CRA LYS A 11  ? UNP O95544 ?   ?   'expression tag'        77  11  
1 9CRA ALA A 12  ? UNP O95544 ?   ?   'expression tag'        78  12  
1 9CRA THR A 13  ? UNP O95544 ?   ?   'expression tag'        79  13  
1 9CRA VAL A 14  ? UNP O95544 ?   ?   'expression tag'        80  14  
1 9CRA GLU A 15  ? UNP O95544 ?   ?   'expression tag'        89  15  
1 9CRA THR A 16  ? UNP O95544 ?   ?   'expression tag'        90  16  
1 9CRA VAL A 22  ? UNP O95544 GLN 96  conflict                96  17  
1 9CRA THR A 88  ? UNP O95544 CYS 162 conflict                162 18  
1 9CRA THR A 328 ? UNP O95544 CYS 402 conflict                402 19  
1 9CRA LEU A 364 ? UNP O95544 ?   ?   'expression tag'        438 20  
1 9CRA GLY A 365 ? UNP O95544 ?   ?   'expression tag'        439 21  
1 9CRA LEU A 366 ? UNP O95544 ?   ?   'expression tag'        440 22  
1 9CRA GLU A 367 ? UNP O95544 ?   ?   'expression tag'        441 23  
1 9CRA HIS A 368 ? UNP O95544 ?   ?   'expression tag'        442 24  
1 9CRA HIS A 369 ? UNP O95544 ?   ?   'expression tag'        443 25  
1 9CRA HIS A 370 ? UNP O95544 ?   ?   'expression tag'        444 26  
1 9CRA HIS A 371 ? UNP O95544 ?   ?   'expression tag'        445 27  
1 9CRA HIS A 372 ? UNP O95544 ?   ?   'expression tag'        446 28  
1 9CRA HIS A 373 ? UNP O95544 ?   ?   'expression tag'        447 29  
2 9CRA MET B 1   ? UNP O95544 ?   ?   'initiating methionine' 67  30  
2 9CRA PRO B 2   ? UNP O95544 ?   ?   'expression tag'        68  31  
2 9CRA SER B 3   ? UNP O95544 ?   ?   'expression tag'        69  32  
2 9CRA PRO B 4   ? UNP O95544 ?   ?   'expression tag'        70  33  
2 9CRA VAL B 5   ? UNP O95544 ?   ?   'expression tag'        71  34  
2 9CRA THR B 6   ? UNP O95544 ?   ?   'expression tag'        72  35  
2 9CRA THR B 7   ? UNP O95544 ?   ?   'expression tag'        73  36  
2 9CRA PHE B 8   ? UNP O95544 ?   ?   'expression tag'        74  37  
2 9CRA GLY B 9   ? UNP O95544 ?   ?   'expression tag'        75  38  
2 9CRA PRO B 10  ? UNP O95544 ?   ?   'expression tag'        76  39  
2 9CRA LYS B 11  ? UNP O95544 ?   ?   'expression tag'        77  40  
2 9CRA ALA B 12  ? UNP O95544 ?   ?   'expression tag'        78  41  
2 9CRA THR B 13  ? UNP O95544 ?   ?   'expression tag'        79  42  
2 9CRA VAL B 14  ? UNP O95544 ?   ?   'expression tag'        80  43  
2 9CRA GLU B 15  ? UNP O95544 ?   ?   'expression tag'        89  44  
2 9CRA THR B 16  ? UNP O95544 ?   ?   'expression tag'        90  45  
2 9CRA VAL B 22  ? UNP O95544 GLN 96  conflict                96  46  
2 9CRA THR B 88  ? UNP O95544 CYS 162 conflict                162 47  
2 9CRA THR B 328 ? UNP O95544 CYS 402 conflict                402 48  
2 9CRA LEU B 364 ? UNP O95544 ?   ?   'expression tag'        438 49  
2 9CRA GLY B 365 ? UNP O95544 ?   ?   'expression tag'        439 50  
2 9CRA LEU B 366 ? UNP O95544 ?   ?   'expression tag'        440 51  
2 9CRA GLU B 367 ? UNP O95544 ?   ?   'expression tag'        441 52  
2 9CRA HIS B 368 ? UNP O95544 ?   ?   'expression tag'        442 53  
2 9CRA HIS B 369 ? UNP O95544 ?   ?   'expression tag'        443 54  
2 9CRA HIS B 370 ? UNP O95544 ?   ?   'expression tag'        444 55  
2 9CRA HIS B 371 ? UNP O95544 ?   ?   'expression tag'        445 56  
2 9CRA HIS B 372 ? UNP O95544 ?   ?   'expression tag'        446 57  
2 9CRA HIS B 373 ? UNP O95544 ?   ?   'expression tag'        447 58  
3 9CRA MET C 1   ? UNP O95544 ?   ?   'initiating methionine' 67  59  
3 9CRA PRO C 2   ? UNP O95544 ?   ?   'expression tag'        68  60  
3 9CRA SER C 3   ? UNP O95544 ?   ?   'expression tag'        69  61  
3 9CRA PRO C 4   ? UNP O95544 ?   ?   'expression tag'        70  62  
3 9CRA VAL C 5   ? UNP O95544 ?   ?   'expression tag'        71  63  
3 9CRA THR C 6   ? UNP O95544 ?   ?   'expression tag'        72  64  
3 9CRA THR C 7   ? UNP O95544 ?   ?   'expression tag'        73  65  
3 9CRA PHE C 8   ? UNP O95544 ?   ?   'expression tag'        74  66  
3 9CRA GLY C 9   ? UNP O95544 ?   ?   'expression tag'        75  67  
3 9CRA PRO C 10  ? UNP O95544 ?   ?   'expression tag'        76  68  
3 9CRA LYS C 11  ? UNP O95544 ?   ?   'expression tag'        77  69  
3 9CRA ALA C 12  ? UNP O95544 ?   ?   'expression tag'        78  70  
3 9CRA THR C 13  ? UNP O95544 ?   ?   'expression tag'        87  71  
3 9CRA VAL C 14  ? UNP O95544 ?   ?   'expression tag'        88  72  
3 9CRA GLU C 15  ? UNP O95544 ?   ?   'expression tag'        89  73  
3 9CRA THR C 16  ? UNP O95544 ?   ?   'expression tag'        90  74  
3 9CRA VAL C 22  ? UNP O95544 GLN 96  conflict                96  75  
3 9CRA THR C 88  ? UNP O95544 CYS 162 conflict                162 76  
3 9CRA THR C 328 ? UNP O95544 CYS 402 conflict                402 77  
3 9CRA LEU C 364 ? UNP O95544 ?   ?   'expression tag'        438 78  
3 9CRA GLY C 365 ? UNP O95544 ?   ?   'expression tag'        439 79  
3 9CRA LEU C 366 ? UNP O95544 ?   ?   'expression tag'        440 80  
3 9CRA GLU C 367 ? UNP O95544 ?   ?   'expression tag'        441 81  
3 9CRA HIS C 368 ? UNP O95544 ?   ?   'expression tag'        442 82  
3 9CRA HIS C 369 ? UNP O95544 ?   ?   'expression tag'        443 83  
3 9CRA HIS C 370 ? UNP O95544 ?   ?   'expression tag'        444 84  
3 9CRA HIS C 371 ? UNP O95544 ?   ?   'expression tag'        445 85  
3 9CRA HIS C 372 ? UNP O95544 ?   ?   'expression tag'        446 86  
3 9CRA HIS C 373 ? UNP O95544 ?   ?   'expression tag'        447 87  
4 9CRA MET D 1   ? UNP O95544 ?   ?   'initiating methionine' 67  88  
4 9CRA PRO D 2   ? UNP O95544 ?   ?   'expression tag'        68  89  
4 9CRA SER D 3   ? UNP O95544 ?   ?   'expression tag'        69  90  
4 9CRA PRO D 4   ? UNP O95544 ?   ?   'expression tag'        70  91  
4 9CRA VAL D 5   ? UNP O95544 ?   ?   'expression tag'        71  92  
4 9CRA THR D 6   ? UNP O95544 ?   ?   'expression tag'        72  93  
4 9CRA THR D 7   ? UNP O95544 ?   ?   'expression tag'        73  94  
4 9CRA PHE D 8   ? UNP O95544 ?   ?   'expression tag'        74  95  
4 9CRA GLY D 9   ? UNP O95544 ?   ?   'expression tag'        75  96  
4 9CRA PRO D 10  ? UNP O95544 ?   ?   'expression tag'        76  97  
4 9CRA LYS D 11  ? UNP O95544 ?   ?   'expression tag'        77  98  
4 9CRA ALA D 12  ? UNP O95544 ?   ?   'expression tag'        78  99  
4 9CRA THR D 13  ? UNP O95544 ?   ?   'expression tag'        79  100 
4 9CRA VAL D 14  ? UNP O95544 ?   ?   'expression tag'        80  101 
4 9CRA GLU D 15  ? UNP O95544 ?   ?   'expression tag'        89  102 
4 9CRA THR D 16  ? UNP O95544 ?   ?   'expression tag'        90  103 
4 9CRA VAL D 22  ? UNP O95544 GLN 96  conflict                96  104 
4 9CRA THR D 88  ? UNP O95544 CYS 162 conflict                162 105 
4 9CRA THR D 328 ? UNP O95544 CYS 402 conflict                402 106 
4 9CRA LEU D 364 ? UNP O95544 ?   ?   'expression tag'        438 107 
4 9CRA GLY D 365 ? UNP O95544 ?   ?   'expression tag'        439 108 
4 9CRA LEU D 366 ? UNP O95544 ?   ?   'expression tag'        440 109 
4 9CRA GLU D 367 ? UNP O95544 ?   ?   'expression tag'        441 110 
4 9CRA HIS D 368 ? UNP O95544 ?   ?   'expression tag'        442 111 
4 9CRA HIS D 369 ? UNP O95544 ?   ?   'expression tag'        443 112 
4 9CRA HIS D 370 ? UNP O95544 ?   ?   'expression tag'        444 113 
4 9CRA HIS D 371 ? UNP O95544 ?   ?   'expression tag'        445 114 
4 9CRA HIS D 372 ? UNP O95544 ?   ?   'expression tag'        446 115 
4 9CRA HIS D 373 ? UNP O95544 ?   ?   'expression tag'        447 116 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 44  ? MET A 56  ? LEU A 118 MET A 130 1 ? 13 
HELX_P HELX_P2  AA2 GLU A 65  ? GLU A 70  ? GLU A 139 GLU A 144 1 ? 6  
HELX_P HELX_P3  AA3 ASP A 71  ? SER A 76  ? ASP A 145 SER A 150 1 ? 6  
HELX_P HELX_P4  AA4 PHE A 80  ? LYS A 85  ? PHE A 154 LYS A 159 1 ? 6  
HELX_P HELX_P5  AA5 GLY A 109 ? PHE A 120 ? GLY A 183 PHE A 194 1 ? 12 
HELX_P HELX_P6  AA6 ASN A 145 ? GLY A 156 ? ASN A 219 GLY A 230 1 ? 12 
HELX_P HELX_P7  AA7 THR A 246 ? SER A 250 ? THR A 320 SER A 324 5 ? 5  
HELX_P HELX_P8  AA8 ALA A 252 ? ALA A 257 ? ALA A 326 ALA A 331 1 ? 6  
HELX_P HELX_P9  AA9 ASP A 338 ? CYS A 350 ? ASP A 412 CYS A 424 1 ? 13 
HELX_P HELX_P10 AB1 ASP B 41  ? SER B 43  ? ASP B 115 SER B 117 5 ? 3  
HELX_P HELX_P11 AB2 LEU B 44  ? MET B 56  ? LEU B 118 MET B 130 1 ? 13 
HELX_P HELX_P12 AB3 GLU B 65  ? GLU B 70  ? GLU B 139 GLU B 144 1 ? 6  
HELX_P HELX_P13 AB4 ASP B 71  ? SER B 76  ? ASP B 145 SER B 150 1 ? 6  
HELX_P HELX_P14 AB5 GLU B 78  ? LYS B 85  ? GLU B 152 LYS B 159 1 ? 8  
HELX_P HELX_P15 AB6 GLY B 109 ? PHE B 120 ? GLY B 183 PHE B 194 1 ? 12 
HELX_P HELX_P16 AB7 ASN B 145 ? GLY B 156 ? ASN B 219 GLY B 230 1 ? 12 
HELX_P HELX_P17 AB8 PRO B 247 ? THR B 251 ? PRO B 321 THR B 325 5 ? 5  
HELX_P HELX_P18 AB9 ALA B 252 ? ALA B 257 ? ALA B 326 ALA B 331 1 ? 6  
HELX_P HELX_P19 AC1 ASP B 338 ? CYS B 350 ? ASP B 412 CYS B 424 1 ? 13 
HELX_P HELX_P20 AC2 LEU C 44  ? MET C 56  ? LEU C 118 MET C 130 1 ? 13 
HELX_P HELX_P21 AC3 LYS C 66  ? GLU C 70  ? LYS C 140 GLU C 144 1 ? 5  
HELX_P HELX_P22 AC4 ASP C 71  ? SER C 76  ? ASP C 145 SER C 150 1 ? 6  
HELX_P HELX_P23 AC5 ASP C 77  ? LYS C 85  ? ASP C 151 LYS C 159 1 ? 9  
HELX_P HELX_P24 AC6 GLY C 109 ? PHE C 120 ? GLY C 183 PHE C 194 1 ? 12 
HELX_P HELX_P25 AC7 ASN C 145 ? GLY C 156 ? ASN C 219 GLY C 230 1 ? 12 
HELX_P HELX_P26 AC8 PRO C 247 ? THR C 251 ? PRO C 321 THR C 325 5 ? 5  
HELX_P HELX_P27 AC9 ALA C 252 ? ALA C 257 ? ALA C 326 ALA C 331 1 ? 6  
HELX_P HELX_P28 AD1 ASP C 338 ? CYS C 350 ? ASP C 412 CYS C 424 1 ? 13 
HELX_P HELX_P29 AD2 LEU D 45  ? MET D 56  ? LEU D 119 MET D 130 1 ? 12 
HELX_P HELX_P30 AD3 GLU D 65  ? GLU D 70  ? GLU D 139 GLU D 144 1 ? 6  
HELX_P HELX_P31 AD4 ASP D 71  ? SER D 76  ? ASP D 145 SER D 150 1 ? 6  
HELX_P HELX_P32 AD5 PHE D 80  ? LYS D 85  ? PHE D 154 LYS D 159 1 ? 6  
HELX_P HELX_P33 AD6 GLY D 109 ? LEU D 119 ? GLY D 183 LEU D 193 1 ? 11 
HELX_P HELX_P34 AD7 ASN D 145 ? GLY D 156 ? ASN D 219 GLY D 230 1 ? 12 
HELX_P HELX_P35 AD8 THR D 246 ? SER D 250 ? THR D 320 SER D 324 5 ? 5  
HELX_P HELX_P36 AD9 ALA D 252 ? ALA D 257 ? ALA D 326 ALA D 331 1 ? 6  
HELX_P HELX_P37 AE1 ASP D 338 ? CYS D 350 ? ASP D 412 CYS D 424 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 7 ? 
AA4 ? 9 ? 
AA5 ? 3 ? 
AA6 ? 5 ? 
AA7 ? 2 ? 
AA8 ? 6 ? 
AA9 ? 3 ? 
AB1 ? 2 ? 
AB2 ? 6 ? 
AB3 ? 2 ? 
AB4 ? 6 ? 
AB5 ? 3 ? 
AB6 ? 2 ? 
AB7 ? 3 ? 
AB8 ? 3 ? 
AB9 ? 5 ? 
AC1 ? 2 ? 
AC2 ? 6 ? 
AC3 ? 3 ? 
AC4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA4 7 8 ? anti-parallel 
AA4 8 9 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? parallel      
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
AA6 4 5 ? parallel      
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? parallel      
AB2 3 4 ? parallel      
AB2 4 5 ? parallel      
AB2 5 6 ? parallel      
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? parallel      
AB9 1 2 ? parallel      
AB9 2 3 ? parallel      
AB9 3 4 ? parallel      
AB9 4 5 ? parallel      
AC1 1 2 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? anti-parallel 
AC2 5 6 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 61  ? TYR A 63  ? ILE A 135 TYR A 137 
AA1 2 SER A 32  ? ILE A 36  ? SER A 106 ILE A 110 
AA1 3 PHE A 103 ? LEU A 107 ? PHE A 177 LEU A 181 
AA1 4 VAL A 127 ? HIS A 131 ? VAL A 201 HIS A 205 
AA1 5 PHE A 141 ? SER A 142 ? PHE A 215 SER A 216 
AA2 1 ALA A 159 ? ARG A 163 ? ALA A 233 ARG A 237 
AA2 2 LEU A 331 ? CYS A 335 ? LEU A 405 CYS A 409 
AA3 1 MET A 204 ? VAL A 208 ? MET A 278 VAL A 282 
AA3 2 LEU A 166 ? VAL A 171 ? LEU A 240 VAL A 245 
AA3 3 SER A 321 ? THR A 326 ? SER A 395 THR A 400 
AA3 4 LEU A 292 ? LEU A 296 ? LEU A 366 LEU A 370 
AA3 5 SER A 223 ? LEU A 229 ? SER A 297 LEU A 303 
AA3 6 HIS A 232 ? VAL A 242 ? HIS A 306 VAL A 316 
AA3 7 PRO A 273 ? PRO A 276 ? PRO A 347 PRO A 350 
AA4 1 MET A 204 ? VAL A 208 ? MET A 278 VAL A 282 
AA4 2 LEU A 166 ? VAL A 171 ? LEU A 240 VAL A 245 
AA4 3 SER A 321 ? THR A 326 ? SER A 395 THR A 400 
AA4 4 LEU A 292 ? LEU A 296 ? LEU A 366 LEU A 370 
AA4 5 SER A 223 ? LEU A 229 ? SER A 297 LEU A 303 
AA4 6 HIS A 232 ? VAL A 242 ? HIS A 306 VAL A 316 
AA4 7 VAL A 212 ? ASP A 215 ? VAL A 286 ASP A 289 
AA4 8 ALA A 304 ? PHE A 308 ? ALA A 378 PHE A 382 
AA4 9 ARG A 313 ? ILE A 316 ? ARG A 387 ILE A 390 
AA5 1 ALA A 268 ? ILE A 271 ? ALA A 342 ILE A 345 
AA5 2 ILE A 284 ? PRO A 287 ? ILE A 358 PRO A 361 
AA5 3 MET B 261 ? ILE B 262 ? MET B 335 ILE B 336 
AA6 1 ILE B 61  ? TYR B 63  ? ILE B 135 TYR B 137 
AA6 2 SER B 32  ? ILE B 36  ? SER B 106 ILE B 110 
AA6 3 PHE B 103 ? LEU B 107 ? PHE B 177 LEU B 181 
AA6 4 VAL B 127 ? HIS B 131 ? VAL B 201 HIS B 205 
AA6 5 PHE B 141 ? SER B 142 ? PHE B 215 SER B 216 
AA7 1 VAL B 160 ? ARG B 163 ? VAL B 234 ARG B 237 
AA7 2 LEU B 331 ? ILE B 334 ? LEU B 405 ILE B 408 
AA8 1 MET B 204 ? VAL B 208 ? MET B 278 VAL B 282 
AA8 2 LEU B 166 ? VAL B 171 ? LEU B 240 VAL B 245 
AA8 3 SER B 321 ? THR B 326 ? SER B 395 THR B 400 
AA8 4 LEU B 292 ? LEU B 296 ? LEU B 366 LEU B 370 
AA8 5 SER B 223 ? LEU B 229 ? SER B 297 LEU B 303 
AA8 6 HIS B 232 ? GLY B 239 ? HIS B 306 GLY B 313 
AA9 1 VAL B 212 ? ASP B 215 ? VAL B 286 ASP B 289 
AA9 2 ALA B 304 ? PHE B 308 ? ALA B 378 PHE B 382 
AA9 3 ARG B 313 ? ILE B 316 ? ARG B 387 ILE B 390 
AB1 1 ILE B 269 ? ILE B 271 ? ILE B 343 ILE B 345 
AB1 2 ILE B 284 ? VAL B 286 ? ILE B 358 VAL B 360 
AB2 1 THR C 88  ? PHE C 90  ? THR C 162 PHE C 164 
AB2 2 ILE C 61  ? GLU C 65  ? ILE C 135 GLU C 139 
AB2 3 SER C 32  ? ILE C 36  ? SER C 106 ILE C 110 
AB2 4 PHE C 103 ? LEU C 107 ? PHE C 177 LEU C 181 
AB2 5 VAL C 127 ? HIS C 131 ? VAL C 201 HIS C 205 
AB2 6 PHE C 141 ? SER C 142 ? PHE C 215 SER C 216 
AB3 1 VAL C 160 ? ARG C 163 ? VAL C 234 ARG C 237 
AB3 2 LEU C 331 ? ILE C 334 ? LEU C 405 ILE C 408 
AB4 1 TYR C 206 ? VAL C 208 ? TYR C 280 VAL C 282 
AB4 2 LEU C 166 ? VAL C 171 ? LEU C 240 VAL C 245 
AB4 3 SER C 321 ? THR C 326 ? SER C 395 THR C 400 
AB4 4 LEU C 292 ? LEU C 296 ? LEU C 366 LEU C 370 
AB4 5 SER C 223 ? LEU C 229 ? SER C 297 LEU C 303 
AB4 6 LEU C 233 ? GLY C 239 ? LEU C 307 GLY C 313 
AB5 1 VAL C 212 ? ASP C 215 ? VAL C 286 ASP C 289 
AB5 2 ALA C 304 ? PHE C 308 ? ALA C 378 PHE C 382 
AB5 3 ARG C 313 ? ILE C 316 ? ARG C 387 ILE C 390 
AB6 1 GLY C 241 ? VAL C 242 ? GLY C 315 VAL C 316 
AB6 2 PRO C 273 ? ILE C 274 ? PRO C 347 ILE C 348 
AB7 1 MET C 261 ? ILE C 262 ? MET C 335 ILE C 336 
AB7 2 ILE D 284 ? PRO D 287 ? ILE D 358 PRO D 361 
AB7 3 ALA D 268 ? ILE D 271 ? ALA D 342 ILE D 345 
AB8 1 ALA C 268 ? ILE C 271 ? ALA C 342 ILE C 345 
AB8 2 ILE C 284 ? PRO C 287 ? ILE C 358 PRO C 361 
AB8 3 MET D 261 ? ILE D 262 ? MET D 335 ILE D 336 
AB9 1 ILE D 61  ? TYR D 63  ? ILE D 135 TYR D 137 
AB9 2 SER D 32  ? ILE D 36  ? SER D 106 ILE D 110 
AB9 3 PHE D 103 ? LEU D 107 ? PHE D 177 LEU D 181 
AB9 4 VAL D 127 ? HIS D 131 ? VAL D 201 HIS D 205 
AB9 5 PHE D 141 ? SER D 142 ? PHE D 215 SER D 216 
AC1 1 ALA D 159 ? ARG D 163 ? ALA D 233 ARG D 237 
AC1 2 LEU D 331 ? CYS D 335 ? LEU D 405 CYS D 409 
AC2 1 TYR D 206 ? VAL D 208 ? TYR D 280 VAL D 282 
AC2 2 LEU D 166 ? VAL D 171 ? LEU D 240 VAL D 245 
AC2 3 SER D 321 ? THR D 326 ? SER D 395 THR D 400 
AC2 4 LEU D 292 ? LEU D 296 ? LEU D 366 LEU D 370 
AC2 5 SER D 223 ? LEU D 229 ? SER D 297 LEU D 303 
AC2 6 HIS D 232 ? GLY D 239 ? HIS D 306 GLY D 313 
AC3 1 VAL D 212 ? ASP D 215 ? VAL D 286 ASP D 289 
AC3 2 ALA D 304 ? PHE D 308 ? ALA D 378 PHE D 382 
AC3 3 ARG D 311 ? ILE D 316 ? ARG D 385 ILE D 390 
AC4 1 GLY D 241 ? VAL D 242 ? GLY D 315 VAL D 316 
AC4 2 PRO D 273 ? ILE D 274 ? PRO D 347 ILE D 348 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 61  ? O ILE A 135 N VAL A 33  ? N VAL A 107 
AA1 2 3 N LEU A 34  ? N LEU A 108 O ILE A 105 ? O ILE A 179 
AA1 3 4 N ILE A 104 ? N ILE A 178 O MET A 128 ? O MET A 202 
AA1 4 5 N HIS A 131 ? N HIS A 205 O PHE A 141 ? O PHE A 215 
AA2 1 2 N ARG A 163 ? N ARG A 237 O LEU A 331 ? O LEU A 405 
AA3 1 2 O TYR A 206 ? O TYR A 280 N VAL A 168 ? N VAL A 242 
AA3 2 3 N ARG A 169 ? N ARG A 243 O SER A 323 ? O SER A 397 
AA3 3 4 O ILE A 324 ? O ILE A 398 N LEU A 292 ? N LEU A 366 
AA3 4 5 O MET A 295 ? O MET A 369 N ASP A 226 ? N ASP A 300 
AA3 5 6 N VAL A 227 ? N VAL A 301 O THR A 235 ? O THR A 309 
AA3 6 7 N ASP A 240 ? N ASP A 314 O ILE A 274 ? O ILE A 348 
AA4 1 2 O TYR A 206 ? O TYR A 280 N VAL A 168 ? N VAL A 242 
AA4 2 3 N ARG A 169 ? N ARG A 243 O SER A 323 ? O SER A 397 
AA4 3 4 O ILE A 324 ? O ILE A 398 N LEU A 292 ? N LEU A 366 
AA4 4 5 O MET A 295 ? O MET A 369 N ASP A 226 ? N ASP A 300 
AA4 5 6 N VAL A 227 ? N VAL A 301 O THR A 235 ? O THR A 309 
AA4 6 7 O VAL A 242 ? O VAL A 316 N ILE A 214 ? N ILE A 288 
AA4 7 8 N ASP A 215 ? N ASP A 289 O TRP A 305 ? O TRP A 379 
AA4 8 9 N ALA A 304 ? N ALA A 378 O ILE A 316 ? O ILE A 390 
AA5 1 2 N ILE A 269 ? N ILE A 343 O VAL A 286 ? O VAL A 360 
AA5 2 3 N VAL A 285 ? N VAL A 359 O MET B 261 ? O MET B 335 
AA6 1 2 O TYR B 63  ? O TYR B 137 N VAL B 33  ? N VAL B 107 
AA6 2 3 N LEU B 34  ? N LEU B 108 O ILE B 105 ? O ILE B 179 
AA6 3 4 N ILE B 104 ? N ILE B 178 O MET B 128 ? O MET B 202 
AA6 4 5 N HIS B 131 ? N HIS B 205 O PHE B 141 ? O PHE B 215 
AA7 1 2 N ARG B 163 ? N ARG B 237 O LEU B 331 ? O LEU B 405 
AA8 1 2 O TYR B 206 ? O TYR B 280 N VAL B 168 ? N VAL B 242 
AA8 2 3 N VAL B 171 ? N VAL B 245 O SER B 321 ? O SER B 395 
AA8 3 4 O ILE B 324 ? O ILE B 398 N LEU B 292 ? N LEU B 366 
AA8 4 5 O MET B 295 ? O MET B 369 N ASP B 226 ? N ASP B 300 
AA8 5 6 N LEU B 229 ? N LEU B 303 O HIS B 232 ? O HIS B 306 
AA9 1 2 N ASP B 215 ? N ASP B 289 O TRP B 305 ? O TRP B 379 
AA9 2 3 N ALA B 304 ? N ALA B 378 O ILE B 316 ? O ILE B 390 
AB1 1 2 N ILE B 271 ? N ILE B 345 O ILE B 284 ? O ILE B 358 
AB2 1 2 O THR C 88  ? O THR C 162 N VAL C 64  ? N VAL C 138 
AB2 2 3 O ILE C 61  ? O ILE C 135 N VAL C 33  ? N VAL C 107 
AB2 3 4 N LEU C 34  ? N LEU C 108 O ILE C 105 ? O ILE C 179 
AB2 4 5 N CYS C 106 ? N CYS C 180 O MET C 128 ? O MET C 202 
AB2 5 6 N HIS C 131 ? N HIS C 205 O PHE C 141 ? O PHE C 215 
AB3 1 2 N ARG C 163 ? N ARG C 237 O LEU C 331 ? O LEU C 405 
AB4 1 2 O TYR C 206 ? O TYR C 280 N VAL C 168 ? N VAL C 242 
AB4 2 3 N ARG C 169 ? N ARG C 243 O SER C 323 ? O SER C 397 
AB4 3 4 O ILE C 324 ? O ILE C 398 N LEU C 292 ? N LEU C 366 
AB4 4 5 O MET C 295 ? O MET C 369 N ASP C 226 ? N ASP C 300 
AB4 5 6 N VAL C 225 ? N VAL C 299 O VAL C 237 ? O VAL C 311 
AB5 1 2 N ASP C 215 ? N ASP C 289 O TRP C 305 ? O TRP C 379 
AB5 2 3 N ALA C 304 ? N ALA C 378 O ILE C 316 ? O ILE C 390 
AB6 1 2 N GLY C 241 ? N GLY C 315 O ILE C 274 ? O ILE C 348 
AB7 1 2 N MET C 261 ? N MET C 335 O VAL D 285 ? O VAL D 359 
AB7 2 3 O VAL D 286 ? O VAL D 360 N ILE D 269 ? N ILE D 343 
AB8 1 2 N ILE C 269 ? N ILE C 343 O VAL C 286 ? O VAL C 360 
AB8 2 3 N VAL C 285 ? N VAL C 359 O MET D 261 ? O MET D 335 
AB9 1 2 O TYR D 63  ? O TYR D 137 N VAL D 33  ? N VAL D 107 
AB9 2 3 N LEU D 34  ? N LEU D 108 O ILE D 105 ? O ILE D 179 
AB9 3 4 N CYS D 106 ? N CYS D 180 O PHE D 130 ? O PHE D 204 
AB9 4 5 N HIS D 131 ? N HIS D 205 O PHE D 141 ? O PHE D 215 
AC1 1 2 N ARG D 163 ? N ARG D 237 O LEU D 331 ? O LEU D 405 
AC2 1 2 O TYR D 206 ? O TYR D 280 N VAL D 168 ? N VAL D 242 
AC2 2 3 N VAL D 171 ? N VAL D 245 O SER D 321 ? O SER D 395 
AC2 3 4 O ILE D 324 ? O ILE D 398 N LEU D 292 ? N LEU D 366 
AC2 4 5 O LYS D 293 ? O LYS D 367 N TYR D 228 ? N TYR D 302 
AC2 5 6 N LEU D 229 ? N LEU D 303 O HIS D 232 ? O HIS D 306 
AC3 1 2 N ASP D 215 ? N ASP D 289 O TRP D 305 ? O TRP D 379 
AC3 2 3 N PHE D 308 ? N PHE D 382 O ARG D 311 ? O ARG D 385 
AC4 1 2 N GLY D 241 ? N GLY D 315 O ILE D 274 ? O ILE D 348 
# 
_pdbx_entry_details.entry_id                   9CRA 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 101 ? ? 62.88   -70.29  
2  1 MET A 113 ? ? 61.73   -123.09 
3  1 ARG A 114 ? ? -68.41  98.99   
4  1 ALA A 147 ? ? -94.83  49.37   
5  1 ASP A 167 ? ? 68.54   -4.21   
6  1 SER A 172 ? ? 47.10   -121.22 
7  1 CYS A 349 ? ? 53.14   71.97   
8  1 HIS A 351 ? ? -88.50  49.84   
9  1 ASN A 376 ? ? 64.07   172.30  
10 1 ARG A 391 ? ? -104.28 -169.60 
11 1 ASN B 101 ? ? 61.49   -66.99  
12 1 MET B 113 ? ? 49.20   -122.03 
13 1 ALA B 147 ? ? -93.45  47.71   
14 1 LYS B 159 ? ? -66.06  2.31    
15 1 ASN B 173 ? ? 37.63   37.21   
16 1 ASN B 284 ? ? -94.90  -62.15  
17 1 ASP B 289 ? ? -126.24 -165.86 
18 1 ASN B 376 ? ? 63.84   171.76  
19 1 ASN C 101 ? ? 62.71   -70.35  
20 1 GLU C 166 ? ? 68.22   -3.84   
21 1 SER C 172 ? ? -140.26 -159.83 
22 1 SER C 208 ? ? 57.67   -153.41 
23 1 ASN C 284 ? ? -93.10  -61.34  
24 1 GLU C 373 ? ? -97.24  59.40   
25 1 ASN C 376 ? ? 65.86   164.80  
26 1 LYS C 386 ? ? -38.91  122.61  
27 1 ASN D 101 ? ? 61.45   -66.42  
28 1 MET D 113 ? ? 64.89   -126.36 
29 1 LYS D 160 ? ? -93.75  30.49   
30 1 GLU D 166 ? ? 71.05   -7.32   
31 1 SER D 208 ? ? 55.65   -155.10 
32 1 ASN D 376 ? ? 66.63   159.42  
33 1 ARG D 391 ? ? -103.16 -169.16 
34 1 ARG D 411 ? ? -120.72 -54.20  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9CRA 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9CRA 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.34 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               251813 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '50 mM Tris (pH 7.8), 50 mM NaCl, and 2 mM DTT.' 
_em_buffer.pH            7.8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'human NAD Kinase' 
_em_entity_assembly.details              'Tetramer of c-terminally truncated form of human NAD Kinase bound to NAD' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9CRA 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           165000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        C-flat-1.2/1.3 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9CRA 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   278 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9CRA 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9CRA 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        D2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 67  ? A MET 1   
2   1 Y 1 A PRO 68  ? A PRO 2   
3   1 Y 1 A SER 69  ? A SER 3   
4   1 Y 1 A PRO 70  ? A PRO 4   
5   1 Y 1 A VAL 71  ? A VAL 5   
6   1 Y 1 A THR 72  ? A THR 6   
7   1 Y 1 A GLU 89  ? A GLU 15  
8   1 Y 1 A THR 90  ? A THR 16  
9   1 Y 1 A GLN 91  ? A GLN 17  
10  1 Y 1 A ASP 92  ? A ASP 18  
11  1 Y 1 A PRO 93  ? A PRO 19  
12  1 Y 1 A ALA 94  ? A ALA 20  
13  1 Y 1 A SER 95  ? A SER 21  
14  1 Y 1 A GLU 247 ? A GLU 173 
15  1 Y 1 A LEU 248 ? A LEU 174 
16  1 Y 1 A ARG 249 ? A ARG 175 
17  1 Y 1 A GLY 250 ? A GLY 176 
18  1 Y 1 A LYS 251 ? A LYS 177 
19  1 Y 1 A LYS 252 ? A LYS 178 
20  1 Y 1 A THR 253 ? A THR 179 
21  1 Y 1 A ALA 254 ? A ALA 180 
22  1 Y 1 A VAL 255 ? A VAL 181 
23  1 Y 1 A HIS 256 ? A HIS 182 
24  1 Y 1 A ASN 257 ? A ASN 183 
25  1 Y 1 A GLY 258 ? A GLY 184 
26  1 Y 1 A LEU 259 ? A LEU 185 
27  1 Y 1 A GLY 260 ? A GLY 186 
28  1 Y 1 A GLU 261 ? A GLU 187 
29  1 Y 1 A ASN 262 ? A ASN 188 
30  1 Y 1 A GLY 263 ? A GLY 189 
31  1 Y 1 A SER 264 ? A SER 190 
32  1 Y 1 A GLN 265 ? A GLN 191 
33  1 Y 1 A ALA 266 ? A ALA 192 
34  1 Y 1 A ALA 267 ? A ALA 193 
35  1 Y 1 A GLY 268 ? A GLY 194 
36  1 Y 1 A LEU 269 ? A LEU 195 
37  1 Y 1 A ASP 270 ? A ASP 196 
38  1 Y 1 A MET 271 ? A MET 197 
39  1 Y 1 A ASP 272 ? A ASP 198 
40  1 Y 1 A VAL 273 ? A VAL 199 
41  1 Y 1 A GLY 274 ? A GLY 200 
42  1 Y 1 A LYS 275 ? A LYS 201 
43  1 Y 1 A GLN 276 ? A GLN 202 
44  1 Y 1 A LYS 431 ? A LYS 357 
45  1 Y 1 A LYS 432 ? A LYS 358 
46  1 Y 1 A GLN 433 ? A GLN 359 
47  1 Y 1 A ALA 434 ? A ALA 360 
48  1 Y 1 A HIS 435 ? A HIS 361 
49  1 Y 1 A PHE 436 ? A PHE 362 
50  1 Y 1 A GLU 437 ? A GLU 363 
51  1 Y 1 A LEU 438 ? A LEU 364 
52  1 Y 1 A GLY 439 ? A GLY 365 
53  1 Y 1 A LEU 440 ? A LEU 366 
54  1 Y 1 A GLU 441 ? A GLU 367 
55  1 Y 1 A HIS 442 ? A HIS 368 
56  1 Y 1 A HIS 443 ? A HIS 369 
57  1 Y 1 A HIS 444 ? A HIS 370 
58  1 Y 1 A HIS 445 ? A HIS 371 
59  1 Y 1 A HIS 446 ? A HIS 372 
60  1 Y 1 A HIS 447 ? A HIS 373 
61  1 Y 1 B MET 67  ? B MET 1   
62  1 Y 1 B PRO 68  ? B PRO 2   
63  1 Y 1 B SER 69  ? B SER 3   
64  1 Y 1 B PRO 70  ? B PRO 4   
65  1 Y 1 B VAL 71  ? B VAL 5   
66  1 Y 1 B THR 72  ? B THR 6   
67  1 Y 1 B GLU 89  ? B GLU 15  
68  1 Y 1 B THR 90  ? B THR 16  
69  1 Y 1 B GLN 91  ? B GLN 17  
70  1 Y 1 B ASP 92  ? B ASP 18  
71  1 Y 1 B PRO 93  ? B PRO 19  
72  1 Y 1 B ALA 94  ? B ALA 20  
73  1 Y 1 B SER 95  ? B SER 21  
74  1 Y 1 B GLU 166 ? B GLU 92  
75  1 Y 1 B ASP 167 ? B ASP 93  
76  1 Y 1 B TYR 168 ? B TYR 94  
77  1 Y 1 B ASP 169 ? B ASP 95  
78  1 Y 1 B ASP 170 ? B ASP 96  
79  1 Y 1 B ILE 171 ? B ILE 97  
80  1 Y 1 B LEU 248 ? B LEU 174 
81  1 Y 1 B ARG 249 ? B ARG 175 
82  1 Y 1 B GLY 250 ? B GLY 176 
83  1 Y 1 B LYS 251 ? B LYS 177 
84  1 Y 1 B LYS 252 ? B LYS 178 
85  1 Y 1 B THR 253 ? B THR 179 
86  1 Y 1 B ALA 254 ? B ALA 180 
87  1 Y 1 B VAL 255 ? B VAL 181 
88  1 Y 1 B HIS 256 ? B HIS 182 
89  1 Y 1 B ASN 257 ? B ASN 183 
90  1 Y 1 B GLY 258 ? B GLY 184 
91  1 Y 1 B LEU 259 ? B LEU 185 
92  1 Y 1 B GLY 260 ? B GLY 186 
93  1 Y 1 B GLU 261 ? B GLU 187 
94  1 Y 1 B ASN 262 ? B ASN 188 
95  1 Y 1 B GLY 263 ? B GLY 189 
96  1 Y 1 B SER 264 ? B SER 190 
97  1 Y 1 B GLN 265 ? B GLN 191 
98  1 Y 1 B ALA 266 ? B ALA 192 
99  1 Y 1 B ALA 267 ? B ALA 193 
100 1 Y 1 B GLY 268 ? B GLY 194 
101 1 Y 1 B LEU 269 ? B LEU 195 
102 1 Y 1 B ASP 270 ? B ASP 196 
103 1 Y 1 B MET 271 ? B MET 197 
104 1 Y 1 B ASP 272 ? B ASP 198 
105 1 Y 1 B VAL 273 ? B VAL 199 
106 1 Y 1 B GLY 274 ? B GLY 200 
107 1 Y 1 B LYS 275 ? B LYS 201 
108 1 Y 1 B LYS 431 ? B LYS 357 
109 1 Y 1 B LYS 432 ? B LYS 358 
110 1 Y 1 B GLN 433 ? B GLN 359 
111 1 Y 1 B ALA 434 ? B ALA 360 
112 1 Y 1 B HIS 435 ? B HIS 361 
113 1 Y 1 B PHE 436 ? B PHE 362 
114 1 Y 1 B GLU 437 ? B GLU 363 
115 1 Y 1 B LEU 438 ? B LEU 364 
116 1 Y 1 B GLY 439 ? B GLY 365 
117 1 Y 1 B LEU 440 ? B LEU 366 
118 1 Y 1 B GLU 441 ? B GLU 367 
119 1 Y 1 B HIS 442 ? B HIS 368 
120 1 Y 1 B HIS 443 ? B HIS 369 
121 1 Y 1 B HIS 444 ? B HIS 370 
122 1 Y 1 B HIS 445 ? B HIS 371 
123 1 Y 1 B HIS 446 ? B HIS 372 
124 1 Y 1 B HIS 447 ? B HIS 373 
125 1 Y 1 C MET 67  ? C MET 1   
126 1 Y 1 C PRO 68  ? C PRO 2   
127 1 Y 1 C SER 69  ? C SER 3   
128 1 Y 1 C PRO 70  ? C PRO 4   
129 1 Y 1 C VAL 71  ? C VAL 5   
130 1 Y 1 C THR 72  ? C THR 6   
131 1 Y 1 C THR 73  ? C THR 7   
132 1 Y 1 C THR 87  ? C THR 13  
133 1 Y 1 C VAL 88  ? C VAL 14  
134 1 Y 1 C GLU 89  ? C GLU 15  
135 1 Y 1 C THR 90  ? C THR 16  
136 1 Y 1 C GLN 91  ? C GLN 17  
137 1 Y 1 C ASP 92  ? C ASP 18  
138 1 Y 1 C PRO 93  ? C PRO 19  
139 1 Y 1 C ALA 94  ? C ALA 20  
140 1 Y 1 C SER 95  ? C SER 21  
141 1 Y 1 C LEU 248 ? C LEU 174 
142 1 Y 1 C ARG 249 ? C ARG 175 
143 1 Y 1 C GLY 250 ? C GLY 176 
144 1 Y 1 C LYS 251 ? C LYS 177 
145 1 Y 1 C LYS 252 ? C LYS 178 
146 1 Y 1 C THR 253 ? C THR 179 
147 1 Y 1 C ALA 254 ? C ALA 180 
148 1 Y 1 C VAL 255 ? C VAL 181 
149 1 Y 1 C HIS 256 ? C HIS 182 
150 1 Y 1 C ASN 257 ? C ASN 183 
151 1 Y 1 C GLY 258 ? C GLY 184 
152 1 Y 1 C LEU 259 ? C LEU 185 
153 1 Y 1 C GLY 260 ? C GLY 186 
154 1 Y 1 C GLU 261 ? C GLU 187 
155 1 Y 1 C ASN 262 ? C ASN 188 
156 1 Y 1 C GLY 263 ? C GLY 189 
157 1 Y 1 C SER 264 ? C SER 190 
158 1 Y 1 C GLN 265 ? C GLN 191 
159 1 Y 1 C ALA 266 ? C ALA 192 
160 1 Y 1 C ALA 267 ? C ALA 193 
161 1 Y 1 C GLY 268 ? C GLY 194 
162 1 Y 1 C LEU 269 ? C LEU 195 
163 1 Y 1 C ASP 270 ? C ASP 196 
164 1 Y 1 C MET 271 ? C MET 197 
165 1 Y 1 C ASP 272 ? C ASP 198 
166 1 Y 1 C VAL 273 ? C VAL 199 
167 1 Y 1 C GLY 274 ? C GLY 200 
168 1 Y 1 C LYS 275 ? C LYS 201 
169 1 Y 1 C GLN 276 ? C GLN 202 
170 1 Y 1 C LYS 431 ? C LYS 357 
171 1 Y 1 C LYS 432 ? C LYS 358 
172 1 Y 1 C GLN 433 ? C GLN 359 
173 1 Y 1 C ALA 434 ? C ALA 360 
174 1 Y 1 C HIS 435 ? C HIS 361 
175 1 Y 1 C PHE 436 ? C PHE 362 
176 1 Y 1 C GLU 437 ? C GLU 363 
177 1 Y 1 C LEU 438 ? C LEU 364 
178 1 Y 1 C GLY 439 ? C GLY 365 
179 1 Y 1 C LEU 440 ? C LEU 366 
180 1 Y 1 C GLU 441 ? C GLU 367 
181 1 Y 1 C HIS 442 ? C HIS 368 
182 1 Y 1 C HIS 443 ? C HIS 369 
183 1 Y 1 C HIS 444 ? C HIS 370 
184 1 Y 1 C HIS 445 ? C HIS 371 
185 1 Y 1 C HIS 446 ? C HIS 372 
186 1 Y 1 C HIS 447 ? C HIS 373 
187 1 Y 1 D MET 67  ? D MET 1   
188 1 Y 1 D PRO 68  ? D PRO 2   
189 1 Y 1 D SER 69  ? D SER 3   
190 1 Y 1 D PRO 70  ? D PRO 4   
191 1 Y 1 D VAL 71  ? D VAL 5   
192 1 Y 1 D THR 72  ? D THR 6   
193 1 Y 1 D GLU 89  ? D GLU 15  
194 1 Y 1 D THR 90  ? D THR 16  
195 1 Y 1 D GLN 91  ? D GLN 17  
196 1 Y 1 D ASP 92  ? D ASP 18  
197 1 Y 1 D PRO 93  ? D PRO 19  
198 1 Y 1 D ALA 94  ? D ALA 20  
199 1 Y 1 D SER 95  ? D SER 21  
200 1 Y 1 D LEU 248 ? D LEU 174 
201 1 Y 1 D ARG 249 ? D ARG 175 
202 1 Y 1 D GLY 250 ? D GLY 176 
203 1 Y 1 D LYS 251 ? D LYS 177 
204 1 Y 1 D LYS 252 ? D LYS 178 
205 1 Y 1 D THR 253 ? D THR 179 
206 1 Y 1 D ALA 254 ? D ALA 180 
207 1 Y 1 D VAL 255 ? D VAL 181 
208 1 Y 1 D HIS 256 ? D HIS 182 
209 1 Y 1 D ASN 257 ? D ASN 183 
210 1 Y 1 D GLY 258 ? D GLY 184 
211 1 Y 1 D LEU 259 ? D LEU 185 
212 1 Y 1 D GLY 260 ? D GLY 186 
213 1 Y 1 D GLU 261 ? D GLU 187 
214 1 Y 1 D ASN 262 ? D ASN 188 
215 1 Y 1 D GLY 263 ? D GLY 189 
216 1 Y 1 D SER 264 ? D SER 190 
217 1 Y 1 D GLN 265 ? D GLN 191 
218 1 Y 1 D ALA 266 ? D ALA 192 
219 1 Y 1 D ALA 267 ? D ALA 193 
220 1 Y 1 D GLY 268 ? D GLY 194 
221 1 Y 1 D LEU 269 ? D LEU 195 
222 1 Y 1 D ASP 270 ? D ASP 196 
223 1 Y 1 D MET 271 ? D MET 197 
224 1 Y 1 D ASP 272 ? D ASP 198 
225 1 Y 1 D VAL 273 ? D VAL 199 
226 1 Y 1 D GLY 274 ? D GLY 200 
227 1 Y 1 D LYS 275 ? D LYS 201 
228 1 Y 1 D GLN 276 ? D GLN 202 
229 1 Y 1 D LYS 431 ? D LYS 357 
230 1 Y 1 D LYS 432 ? D LYS 358 
231 1 Y 1 D GLN 433 ? D GLN 359 
232 1 Y 1 D ALA 434 ? D ALA 360 
233 1 Y 1 D HIS 435 ? D HIS 361 
234 1 Y 1 D PHE 436 ? D PHE 362 
235 1 Y 1 D GLU 437 ? D GLU 363 
236 1 Y 1 D LEU 438 ? D LEU 364 
237 1 Y 1 D GLY 439 ? D GLY 365 
238 1 Y 1 D LEU 440 ? D LEU 366 
239 1 Y 1 D GLU 441 ? D GLU 367 
240 1 Y 1 D HIS 442 ? D HIS 368 
241 1 Y 1 D HIS 443 ? D HIS 369 
242 1 Y 1 D HIS 444 ? D HIS 370 
243 1 Y 1 D HIS 445 ? D HIS 371 
244 1 Y 1 D HIS 446 ? D HIS 372 
245 1 Y 1 D HIS 447 ? D HIS 373 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAD PA   P N S 247 
NAD O1A  O N N 248 
NAD O2A  O N N 249 
NAD O5B  O N N 250 
NAD C5B  C N N 251 
NAD C4B  C N R 252 
NAD O4B  O N N 253 
NAD C3B  C N S 254 
NAD O3B  O N N 255 
NAD C2B  C N R 256 
NAD O2B  O N N 257 
NAD C1B  C N R 258 
NAD N9A  N Y N 259 
NAD C8A  C Y N 260 
NAD N7A  N Y N 261 
NAD C5A  C Y N 262 
NAD C6A  C Y N 263 
NAD N6A  N N N 264 
NAD N1A  N Y N 265 
NAD C2A  C Y N 266 
NAD N3A  N Y N 267 
NAD C4A  C Y N 268 
NAD O3   O N N 269 
NAD PN   P N N 270 
NAD O1N  O N N 271 
NAD O2N  O N N 272 
NAD O5D  O N N 273 
NAD C5D  C N N 274 
NAD C4D  C N R 275 
NAD O4D  O N N 276 
NAD C3D  C N S 277 
NAD O3D  O N N 278 
NAD C2D  C N R 279 
NAD O2D  O N N 280 
NAD C1D  C N R 281 
NAD N1N  N Y N 282 
NAD C2N  C Y N 283 
NAD C3N  C Y N 284 
NAD C7N  C N N 285 
NAD O7N  O N N 286 
NAD N7N  N N N 287 
NAD C4N  C Y N 288 
NAD C5N  C Y N 289 
NAD C6N  C Y N 290 
NAD HOA2 H N N 291 
NAD H51A H N N 292 
NAD H52A H N N 293 
NAD H4B  H N N 294 
NAD H3B  H N N 295 
NAD HO3A H N N 296 
NAD H2B  H N N 297 
NAD HO2A H N N 298 
NAD H1B  H N N 299 
NAD H8A  H N N 300 
NAD H61A H N N 301 
NAD H62A H N N 302 
NAD H2A  H N N 303 
NAD H51N H N N 304 
NAD H52N H N N 305 
NAD H4D  H N N 306 
NAD H3D  H N N 307 
NAD HO3N H N N 308 
NAD H2D  H N N 309 
NAD HO2N H N N 310 
NAD H1D  H N N 311 
NAD H2N  H N N 312 
NAD H71N H N N 313 
NAD H72N H N N 314 
NAD H4N  H N N 315 
NAD H5N  H N N 316 
NAD H6N  H N N 317 
PHE N    N N N 318 
PHE CA   C N S 319 
PHE C    C N N 320 
PHE O    O N N 321 
PHE CB   C N N 322 
PHE CG   C Y N 323 
PHE CD1  C Y N 324 
PHE CD2  C Y N 325 
PHE CE1  C Y N 326 
PHE CE2  C Y N 327 
PHE CZ   C Y N 328 
PHE OXT  O N N 329 
PHE H    H N N 330 
PHE H2   H N N 331 
PHE HA   H N N 332 
PHE HB2  H N N 333 
PHE HB3  H N N 334 
PHE HD1  H N N 335 
PHE HD2  H N N 336 
PHE HE1  H N N 337 
PHE HE2  H N N 338 
PHE HZ   H N N 339 
PHE HXT  H N N 340 
PRO N    N N N 341 
PRO CA   C N S 342 
PRO C    C N N 343 
PRO O    O N N 344 
PRO CB   C N N 345 
PRO CG   C N N 346 
PRO CD   C N N 347 
PRO OXT  O N N 348 
PRO H    H N N 349 
PRO HA   H N N 350 
PRO HB2  H N N 351 
PRO HB3  H N N 352 
PRO HG2  H N N 353 
PRO HG3  H N N 354 
PRO HD2  H N N 355 
PRO HD3  H N N 356 
PRO HXT  H N N 357 
SER N    N N N 358 
SER CA   C N S 359 
SER C    C N N 360 
SER O    O N N 361 
SER CB   C N N 362 
SER OG   O N N 363 
SER OXT  O N N 364 
SER H    H N N 365 
SER H2   H N N 366 
SER HA   H N N 367 
SER HB2  H N N 368 
SER HB3  H N N 369 
SER HG   H N N 370 
SER HXT  H N N 371 
THR N    N N N 372 
THR CA   C N S 373 
THR C    C N N 374 
THR O    O N N 375 
THR CB   C N R 376 
THR OG1  O N N 377 
THR CG2  C N N 378 
THR OXT  O N N 379 
THR H    H N N 380 
THR H2   H N N 381 
THR HA   H N N 382 
THR HB   H N N 383 
THR HG1  H N N 384 
THR HG21 H N N 385 
THR HG22 H N N 386 
THR HG23 H N N 387 
THR HXT  H N N 388 
TRP N    N N N 389 
TRP CA   C N S 390 
TRP C    C N N 391 
TRP O    O N N 392 
TRP CB   C N N 393 
TRP CG   C Y N 394 
TRP CD1  C Y N 395 
TRP CD2  C Y N 396 
TRP NE1  N Y N 397 
TRP CE2  C Y N 398 
TRP CE3  C Y N 399 
TRP CZ2  C Y N 400 
TRP CZ3  C Y N 401 
TRP CH2  C Y N 402 
TRP OXT  O N N 403 
TRP H    H N N 404 
TRP H2   H N N 405 
TRP HA   H N N 406 
TRP HB2  H N N 407 
TRP HB3  H N N 408 
TRP HD1  H N N 409 
TRP HE1  H N N 410 
TRP HE3  H N N 411 
TRP HZ2  H N N 412 
TRP HZ3  H N N 413 
TRP HH2  H N N 414 
TRP HXT  H N N 415 
TYR N    N N N 416 
TYR CA   C N S 417 
TYR C    C N N 418 
TYR O    O N N 419 
TYR CB   C N N 420 
TYR CG   C Y N 421 
TYR CD1  C Y N 422 
TYR CD2  C Y N 423 
TYR CE1  C Y N 424 
TYR CE2  C Y N 425 
TYR CZ   C Y N 426 
TYR OH   O N N 427 
TYR OXT  O N N 428 
TYR H    H N N 429 
TYR H2   H N N 430 
TYR HA   H N N 431 
TYR HB2  H N N 432 
TYR HB3  H N N 433 
TYR HD1  H N N 434 
TYR HD2  H N N 435 
TYR HE1  H N N 436 
TYR HE2  H N N 437 
TYR HH   H N N 438 
TYR HXT  H N N 439 
VAL N    N N N 440 
VAL CA   C N S 441 
VAL C    C N N 442 
VAL O    O N N 443 
VAL CB   C N N 444 
VAL CG1  C N N 445 
VAL CG2  C N N 446 
VAL OXT  O N N 447 
VAL H    H N N 448 
VAL H2   H N N 449 
VAL HA   H N N 450 
VAL HB   H N N 451 
VAL HG11 H N N 452 
VAL HG12 H N N 453 
VAL HG13 H N N 454 
VAL HG21 H N N 455 
VAL HG22 H N N 456 
VAL HG23 H N N 457 
VAL HXT  H N N 458 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAD PA  O1A  doub N N 235 
NAD PA  O2A  sing N N 236 
NAD PA  O5B  sing N N 237 
NAD PA  O3   sing N N 238 
NAD O2A HOA2 sing N N 239 
NAD O5B C5B  sing N N 240 
NAD C5B C4B  sing N N 241 
NAD C5B H51A sing N N 242 
NAD C5B H52A sing N N 243 
NAD C4B O4B  sing N N 244 
NAD C4B C3B  sing N N 245 
NAD C4B H4B  sing N N 246 
NAD O4B C1B  sing N N 247 
NAD C3B O3B  sing N N 248 
NAD C3B C2B  sing N N 249 
NAD C3B H3B  sing N N 250 
NAD O3B HO3A sing N N 251 
NAD C2B O2B  sing N N 252 
NAD C2B C1B  sing N N 253 
NAD C2B H2B  sing N N 254 
NAD O2B HO2A sing N N 255 
NAD C1B N9A  sing N N 256 
NAD C1B H1B  sing N N 257 
NAD N9A C8A  sing Y N 258 
NAD N9A C4A  sing Y N 259 
NAD C8A N7A  doub Y N 260 
NAD C8A H8A  sing N N 261 
NAD N7A C5A  sing Y N 262 
NAD C5A C6A  sing Y N 263 
NAD C5A C4A  doub Y N 264 
NAD C6A N6A  sing N N 265 
NAD C6A N1A  doub Y N 266 
NAD N6A H61A sing N N 267 
NAD N6A H62A sing N N 268 
NAD N1A C2A  sing Y N 269 
NAD C2A N3A  doub Y N 270 
NAD C2A H2A  sing N N 271 
NAD N3A C4A  sing Y N 272 
NAD O3  PN   sing N N 273 
NAD PN  O1N  doub N N 274 
NAD PN  O2N  sing N N 275 
NAD PN  O5D  sing N N 276 
NAD O5D C5D  sing N N 277 
NAD C5D C4D  sing N N 278 
NAD C5D H51N sing N N 279 
NAD C5D H52N sing N N 280 
NAD C4D O4D  sing N N 281 
NAD C4D C3D  sing N N 282 
NAD C4D H4D  sing N N 283 
NAD O4D C1D  sing N N 284 
NAD C3D O3D  sing N N 285 
NAD C3D C2D  sing N N 286 
NAD C3D H3D  sing N N 287 
NAD O3D HO3N sing N N 288 
NAD C2D O2D  sing N N 289 
NAD C2D C1D  sing N N 290 
NAD C2D H2D  sing N N 291 
NAD O2D HO2N sing N N 292 
NAD C1D N1N  sing N N 293 
NAD C1D H1D  sing N N 294 
NAD N1N C2N  sing Y N 295 
NAD N1N C6N  doub Y N 296 
NAD C2N C3N  doub Y N 297 
NAD C2N H2N  sing N N 298 
NAD C3N C7N  sing N N 299 
NAD C3N C4N  sing Y N 300 
NAD C7N O7N  doub N N 301 
NAD C7N N7N  sing N N 302 
NAD N7N H71N sing N N 303 
NAD N7N H72N sing N N 304 
NAD C4N C5N  doub Y N 305 
NAD C4N H4N  sing N N 306 
NAD C5N C6N  sing Y N 307 
NAD C5N H5N  sing N N 308 
NAD C6N H6N  sing N N 309 
PHE N   CA   sing N N 310 
PHE N   H    sing N N 311 
PHE N   H2   sing N N 312 
PHE CA  C    sing N N 313 
PHE CA  CB   sing N N 314 
PHE CA  HA   sing N N 315 
PHE C   O    doub N N 316 
PHE C   OXT  sing N N 317 
PHE CB  CG   sing N N 318 
PHE CB  HB2  sing N N 319 
PHE CB  HB3  sing N N 320 
PHE CG  CD1  doub Y N 321 
PHE CG  CD2  sing Y N 322 
PHE CD1 CE1  sing Y N 323 
PHE CD1 HD1  sing N N 324 
PHE CD2 CE2  doub Y N 325 
PHE CD2 HD2  sing N N 326 
PHE CE1 CZ   doub Y N 327 
PHE CE1 HE1  sing N N 328 
PHE CE2 CZ   sing Y N 329 
PHE CE2 HE2  sing N N 330 
PHE CZ  HZ   sing N N 331 
PHE OXT HXT  sing N N 332 
PRO N   CA   sing N N 333 
PRO N   CD   sing N N 334 
PRO N   H    sing N N 335 
PRO CA  C    sing N N 336 
PRO CA  CB   sing N N 337 
PRO CA  HA   sing N N 338 
PRO C   O    doub N N 339 
PRO C   OXT  sing N N 340 
PRO CB  CG   sing N N 341 
PRO CB  HB2  sing N N 342 
PRO CB  HB3  sing N N 343 
PRO CG  CD   sing N N 344 
PRO CG  HG2  sing N N 345 
PRO CG  HG3  sing N N 346 
PRO CD  HD2  sing N N 347 
PRO CD  HD3  sing N N 348 
PRO OXT HXT  sing N N 349 
SER N   CA   sing N N 350 
SER N   H    sing N N 351 
SER N   H2   sing N N 352 
SER CA  C    sing N N 353 
SER CA  CB   sing N N 354 
SER CA  HA   sing N N 355 
SER C   O    doub N N 356 
SER C   OXT  sing N N 357 
SER CB  OG   sing N N 358 
SER CB  HB2  sing N N 359 
SER CB  HB3  sing N N 360 
SER OG  HG   sing N N 361 
SER OXT HXT  sing N N 362 
THR N   CA   sing N N 363 
THR N   H    sing N N 364 
THR N   H2   sing N N 365 
THR CA  C    sing N N 366 
THR CA  CB   sing N N 367 
THR CA  HA   sing N N 368 
THR C   O    doub N N 369 
THR C   OXT  sing N N 370 
THR CB  OG1  sing N N 371 
THR CB  CG2  sing N N 372 
THR CB  HB   sing N N 373 
THR OG1 HG1  sing N N 374 
THR CG2 HG21 sing N N 375 
THR CG2 HG22 sing N N 376 
THR CG2 HG23 sing N N 377 
THR OXT HXT  sing N N 378 
TRP N   CA   sing N N 379 
TRP N   H    sing N N 380 
TRP N   H2   sing N N 381 
TRP CA  C    sing N N 382 
TRP CA  CB   sing N N 383 
TRP CA  HA   sing N N 384 
TRP C   O    doub N N 385 
TRP C   OXT  sing N N 386 
TRP CB  CG   sing N N 387 
TRP CB  HB2  sing N N 388 
TRP CB  HB3  sing N N 389 
TRP CG  CD1  doub Y N 390 
TRP CG  CD2  sing Y N 391 
TRP CD1 NE1  sing Y N 392 
TRP CD1 HD1  sing N N 393 
TRP CD2 CE2  doub Y N 394 
TRP CD2 CE3  sing Y N 395 
TRP NE1 CE2  sing Y N 396 
TRP NE1 HE1  sing N N 397 
TRP CE2 CZ2  sing Y N 398 
TRP CE3 CZ3  doub Y N 399 
TRP CE3 HE3  sing N N 400 
TRP CZ2 CH2  doub Y N 401 
TRP CZ2 HZ2  sing N N 402 
TRP CZ3 CH2  sing Y N 403 
TRP CZ3 HZ3  sing N N 404 
TRP CH2 HH2  sing N N 405 
TRP OXT HXT  sing N N 406 
TYR N   CA   sing N N 407 
TYR N   H    sing N N 408 
TYR N   H2   sing N N 409 
TYR CA  C    sing N N 410 
TYR CA  CB   sing N N 411 
TYR CA  HA   sing N N 412 
TYR C   O    doub N N 413 
TYR C   OXT  sing N N 414 
TYR CB  CG   sing N N 415 
TYR CB  HB2  sing N N 416 
TYR CB  HB3  sing N N 417 
TYR CG  CD1  doub Y N 418 
TYR CG  CD2  sing Y N 419 
TYR CD1 CE1  sing Y N 420 
TYR CD1 HD1  sing N N 421 
TYR CD2 CE2  doub Y N 422 
TYR CD2 HD2  sing N N 423 
TYR CE1 CZ   doub Y N 424 
TYR CE1 HE1  sing N N 425 
TYR CE2 CZ   sing Y N 426 
TYR CE2 HE2  sing N N 427 
TYR CZ  OH   sing N N 428 
TYR OH  HH   sing N N 429 
TYR OXT HXT  sing N N 430 
VAL N   CA   sing N N 431 
VAL N   H    sing N N 432 
VAL N   H2   sing N N 433 
VAL CA  C    sing N N 434 
VAL CA  CB   sing N N 435 
VAL CA  HA   sing N N 436 
VAL C   O    doub N N 437 
VAL C   OXT  sing N N 438 
VAL CB  CG1  sing N N 439 
VAL CB  CG2  sing N N 440 
VAL CB  HB   sing N N 441 
VAL CG1 HG11 sing N N 442 
VAL CG1 HG12 sing N N 443 
VAL CG1 HG13 sing N N 444 
VAL CG2 HG21 sing N N 445 
VAL CG2 HG22 sing N N 446 
VAL CG2 HG23 sing N N 447 
VAL OXT HXT  sing N N 448 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-21 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9CRA 
_em_admin.last_update        2025-02-12 
_em_admin.map_release_date   2025-01-08 
_em_admin.title              'CryoEM Structure of the C-terminally truncated form of human NAD Kinase bound to NAD' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 50 mM ? 1 TRIS 
1 50 mM ? 2 NaCl 
1 2  mM ? 3 DTT  
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                49 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               'BL21(DE3)' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     9105 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    10 
_em_imaging_optics.energyfilter_name          'TFS Selectris X' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  'template based picking using a low resolution map' 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1716164 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? cryoSPARC       ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 SerialEM        4 
MASKING                         ? 3  ? ? ? ?               ? 
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC       ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?               ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?               ? 
'MODEL FITTING'                 ? 7  ? 1 ? 'UCSF ChimeraX' ? 
OTHER                           ? 8  ? ? ? ?               ? 
'MODEL REFINEMENT'              ? 9  ? 1 ? PHENIX          ? 
'MODEL REFINEMENT'              ? 10 ? 1 ? Coot            ? 
'INITIAL EULER ASSIGNMENT'      ? 11 1 ? ? cryoSPARC       ? 
'FINAL EULER ASSIGNMENT'        ? 12 1 ? ? cryoSPARC       ? 
CLASSIFICATION                  ? 13 1 ? ? cryoSPARC       ? 
RECONSTRUCTION                  ? 14 1 ? ? cryoSPARC       ? 
'VOLUME SELECTION'              ? 15 1 1 1 ?               ? 
'SERIES ALIGNMENT'              ? 16 1 1 1 ?               ? 
'MOLECULAR REPLACEMENT'         ? 17 1 1 1 ?               ? 
'LATTICE DISTORTION CORRECTION' ? 18 1 1 1 ?               ? 
'SYMMETRY DETERMINATION'        ? 19 1 1 1 ?               ? 
'CRYSTALLOGRAPHY MERGING'       ? 20 1 1 1 ?               ? 
# 
_em_specimen.concentration           0.3 
_em_specimen.details                 'Purified by FPLC. Monodispersed.' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Cancer Institute (NIH/NCI)' 'United States' R01GM143236      1 
'Welch Foundation'                                                  'United States' I-2067-20210327  2 
'Welch Foundation'                                                  'United States' I-2067-20240404  3 
'Agence Nationale de la Recherche (ANR)'                            France          ANR-20-CE18-0025 4 
'Fondation pour la Recherche Medicale (FRM)'                        France          EQU202303016265  5 
# 
_atom_sites.entry_id                    9CRA 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR A 1 7   ? 163.090 137.987 133.551 1.00 78.48  ? 73  THR A N   1 
ATOM   2    C CA  . THR A 1 7   ? 163.001 138.963 134.630 1.00 80.61  ? 73  THR A CA  1 
ATOM   3    C C   . THR A 1 7   ? 161.603 139.566 134.711 1.00 80.60  ? 73  THR A C   1 
ATOM   4    O O   . THR A 1 7   ? 160.954 139.794 133.690 1.00 81.32  ? 73  THR A O   1 
ATOM   5    C CB  . THR A 1 7   ? 164.030 140.096 134.454 1.00 81.85  ? 73  THR A CB  1 
ATOM   6    O OG1 . THR A 1 7   ? 163.844 140.719 133.177 1.00 83.25  ? 73  THR A OG1 1 
ATOM   7    C CG2 . THR A 1 7   ? 165.446 139.549 134.546 1.00 78.45  ? 73  THR A CG2 1 
ATOM   8    N N   . PHE A 1 8   ? 161.145 139.825 135.937 1.00 70.69  ? 74  PHE A N   1 
ATOM   9    C CA  . PHE A 1 8   ? 159.824 140.411 136.185 1.00 69.56  ? 74  PHE A CA  1 
ATOM   10   C C   . PHE A 1 8   ? 160.003 141.488 137.253 1.00 69.97  ? 74  PHE A C   1 
ATOM   11   O O   . PHE A 1 8   ? 159.932 141.207 138.452 1.00 71.77  ? 74  PHE A O   1 
ATOM   12   C CB  . PHE A 1 8   ? 158.817 139.351 136.611 1.00 68.85  ? 74  PHE A CB  1 
ATOM   13   C CG  . PHE A 1 8   ? 158.632 138.254 135.603 1.00 71.49  ? 74  PHE A CG  1 
ATOM   14   C CD1 . PHE A 1 8   ? 157.807 138.435 134.506 1.00 70.02  ? 74  PHE A CD1 1 
ATOM   15   C CD2 . PHE A 1 8   ? 159.284 137.042 135.752 1.00 70.42  ? 74  PHE A CD2 1 
ATOM   16   C CE1 . PHE A 1 8   ? 157.635 137.427 133.577 1.00 69.73  ? 74  PHE A CE1 1 
ATOM   17   C CE2 . PHE A 1 8   ? 159.116 136.030 134.826 1.00 71.04  ? 74  PHE A CE2 1 
ATOM   18   C CZ  . PHE A 1 8   ? 158.290 136.224 133.737 1.00 70.98  ? 74  PHE A CZ  1 
ATOM   19   N N   . GLY A 1 9   ? 160.229 142.720 136.809 1.00 69.45  ? 75  GLY A N   1 
ATOM   20   C CA  . GLY A 1 9   ? 160.486 143.816 137.711 1.00 70.03  ? 75  GLY A CA  1 
ATOM   21   C C   . GLY A 1 9   ? 161.968 144.034 137.934 1.00 72.29  ? 75  GLY A C   1 
ATOM   22   O O   . GLY A 1 9   ? 162.813 143.294 137.422 1.00 71.75  ? 75  GLY A O   1 
ATOM   23   N N   . PRO A 1 10  ? 162.310 145.074 138.699 1.00 70.72  ? 76  PRO A N   1 
ATOM   24   C CA  . PRO A 1 10  ? 163.732 145.376 138.933 1.00 70.79  ? 76  PRO A CA  1 
ATOM   25   C C   . PRO A 1 10  ? 164.505 144.250 139.600 1.00 71.98  ? 76  PRO A C   1 
ATOM   26   O O   . PRO A 1 10  ? 165.689 144.064 139.292 1.00 70.23  ? 76  PRO A O   1 
ATOM   27   C CB  . PRO A 1 10  ? 163.678 146.624 139.826 1.00 68.15  ? 76  PRO A CB  1 
ATOM   28   C CG  . PRO A 1 10  ? 162.358 147.245 139.527 1.00 65.77  ? 76  PRO A CG  1 
ATOM   29   C CD  . PRO A 1 10  ? 161.423 146.105 139.262 1.00 66.48  ? 76  PRO A CD  1 
ATOM   30   N N   . LYS A 1 11  ? 163.882 143.494 140.499 1.00 72.39  ? 77  LYS A N   1 
ATOM   31   C CA  . LYS A 1 11  ? 164.597 142.482 141.269 1.00 70.87  ? 77  LYS A CA  1 
ATOM   32   C C   . LYS A 1 11  ? 164.015 141.085 141.137 1.00 70.43  ? 77  LYS A C   1 
ATOM   33   O O   . LYS A 1 11  ? 164.773 140.112 141.106 1.00 71.61  ? 77  LYS A O   1 
ATOM   34   C CB  . LYS A 1 11  ? 164.630 142.878 142.753 1.00 70.31  ? 77  LYS A CB  1 
ATOM   35   C CG  . LYS A 1 11  ? 165.442 144.131 143.041 1.00 70.87  ? 77  LYS A CG  1 
ATOM   36   C CD  . LYS A 1 11  ? 165.454 144.455 144.526 1.00 70.27  ? 77  LYS A CD  1 
ATOM   37   C CE  . LYS A 1 11  ? 166.340 145.654 144.823 1.00 69.80  ? 77  LYS A CE  1 
ATOM   38   N NZ  . LYS A 1 11  ? 165.785 146.909 144.246 1.00 69.83  ? 77  LYS A NZ  1 
ATOM   39   N N   . ALA A 1 12  ? 162.694 140.952 141.064 1.00 73.73  ? 78  ALA A N   1 
ATOM   40   C CA  . ALA A 1 12  ? 162.078 139.633 141.012 1.00 74.09  ? 78  ALA A CA  1 
ATOM   41   C C   . ALA A 1 12  ? 162.382 138.941 139.689 1.00 75.46  ? 78  ALA A C   1 
ATOM   42   O O   . ALA A 1 12  ? 162.454 139.579 138.635 1.00 75.14  ? 78  ALA A O   1 
ATOM   43   C CB  . ALA A 1 12  ? 160.569 139.742 141.213 1.00 73.79  ? 78  ALA A CB  1 
ATOM   44   N N   . THR A 1 13  ? 162.558 137.623 139.752 1.00 76.42  ? 79  THR A N   1 
ATOM   45   C CA  . THR A 1 13  ? 162.862 136.825 138.572 1.00 77.84  ? 79  THR A CA  1 
ATOM   46   C C   . THR A 1 13  ? 162.451 135.385 138.843 1.00 78.58  ? 79  THR A C   1 
ATOM   47   O O   . THR A 1 13  ? 162.202 134.992 139.985 1.00 78.62  ? 79  THR A O   1 
ATOM   48   C CB  . THR A 1 13  ? 164.357 136.908 138.212 1.00 76.95  ? 79  THR A CB  1 
ATOM   49   O OG1 . THR A 1 13  ? 165.143 136.443 139.314 1.00 76.09  ? 79  THR A OG1 1 
ATOM   50   C CG2 . THR A 1 13  ? 164.790 138.359 138.061 1.00 76.39  ? 79  THR A CG2 1 
ATOM   51   N N   . VAL A 1 14  ? 162.378 134.601 137.772 1.00 81.79  ? 80  VAL A N   1 
ATOM   52   C CA  . VAL A 1 14  ? 162.029 133.190 137.883 1.00 80.88  ? 80  VAL A CA  1 
ATOM   53   C C   . VAL A 1 14  ? 163.234 132.321 137.543 1.00 80.71  ? 80  VAL A C   1 
ATOM   54   O O   . VAL A 1 14  ? 164.210 132.796 136.963 1.00 81.26  ? 80  VAL A O   1 
ATOM   55   C CB  . VAL A 1 14  ? 160.834 132.836 136.982 1.00 79.90  ? 80  VAL A CB  1 
ATOM   56   C CG1 . VAL A 1 14  ? 159.589 133.583 137.435 1.00 79.12  ? 80  VAL A CG1 1 
ATOM   57   C CG2 . VAL A 1 14  ? 161.155 133.149 135.529 1.00 79.67  ? 80  VAL A CG2 1 
ATOM   58   N N   . VAL A 1 22  ? 156.932 126.546 138.553 1.00 52.27  ? 96  VAL A N   1 
ATOM   59   C CA  . VAL A 1 22  ? 157.580 127.848 138.463 1.00 54.28  ? 96  VAL A CA  1 
ATOM   60   C C   . VAL A 1 22  ? 157.691 128.475 139.847 1.00 56.97  ? 96  VAL A C   1 
ATOM   61   O O   . VAL A 1 22  ? 156.683 128.798 140.475 1.00 55.57  ? 96  VAL A O   1 
ATOM   62   C CB  . VAL A 1 22  ? 156.825 128.780 137.501 1.00 55.47  ? 96  VAL A CB  1 
ATOM   63   C CG1 . VAL A 1 22  ? 157.451 130.165 137.504 1.00 53.49  ? 96  VAL A CG1 1 
ATOM   64   C CG2 . VAL A 1 22  ? 156.814 128.196 136.098 1.00 55.56  ? 96  VAL A CG2 1 
ATOM   65   N N   . ARG A 1 23  ? 158.923 128.645 140.316 1.00 66.28  ? 97  ARG A N   1 
ATOM   66   C CA  . ARG A 1 23  ? 159.198 129.208 141.628 1.00 63.46  ? 97  ARG A CA  1 
ATOM   67   C C   . ARG A 1 23  ? 159.693 130.641 141.492 1.00 65.32  ? 97  ARG A C   1 
ATOM   68   O O   . ARG A 1 23  ? 160.258 131.028 140.465 1.00 66.92  ? 97  ARG A O   1 
ATOM   69   C CB  . ARG A 1 23  ? 160.233 128.369 142.382 1.00 63.62  ? 97  ARG A CB  1 
ATOM   70   C CG  . ARG A 1 23  ? 159.737 126.991 142.783 1.00 64.32  ? 97  ARG A CG  1 
ATOM   71   C CD  . ARG A 1 23  ? 160.810 126.210 143.522 1.00 66.26  ? 97  ARG A CD  1 
ATOM   72   N NE  . ARG A 1 23  ? 160.338 124.894 143.934 1.00 69.94  ? 97  ARG A NE  1 
ATOM   73   C CZ  . ARG A 1 23  ? 160.454 123.794 143.201 1.00 69.22  ? 97  ARG A CZ  1 
ATOM   74   N NH1 . ARG A 1 23  ? 161.022 123.816 142.007 1.00 66.43  ? 97  ARG A NH1 1 
ATOM   75   N NH2 . ARG A 1 23  ? 159.986 122.644 143.679 1.00 66.10  ? 97  ARG A NH2 1 
ATOM   76   N N   . LEU A 1 24  ? 159.474 131.427 142.542 1.00 60.88  ? 98  LEU A N   1 
ATOM   77   C CA  . LEU A 1 24  ? 159.847 132.834 142.567 1.00 59.08  ? 98  LEU A CA  1 
ATOM   78   C C   . LEU A 1 24  ? 161.185 132.986 143.281 1.00 59.25  ? 98  LEU A C   1 
ATOM   79   O O   . LEU A 1 24  ? 161.333 132.556 144.430 1.00 62.18  ? 98  LEU A O   1 
ATOM   80   C CB  . LEU A 1 24  ? 158.768 133.665 143.260 1.00 56.12  ? 98  LEU A CB  1 
ATOM   81   C CG  . LEU A 1 24  ? 159.039 135.159 143.437 1.00 58.02  ? 98  LEU A CG  1 
ATOM   82   C CD1 . LEU A 1 24  ? 159.209 135.837 142.086 1.00 59.33  ? 98  LEU A CD1 1 
ATOM   83   C CD2 . LEU A 1 24  ? 157.917 135.810 144.230 1.00 58.53  ? 98  LEU A CD2 1 
ATOM   84   N N   . THR A 1 25  ? 162.152 133.596 142.600 1.00 63.64  ? 99  THR A N   1 
ATOM   85   C CA  . THR A 1 25  ? 163.473 133.857 143.154 1.00 62.04  ? 99  THR A CA  1 
ATOM   86   C C   . THR A 1 25  ? 163.686 135.362 143.226 1.00 61.27  ? 99  THR A C   1 
ATOM   87   O O   . THR A 1 25  ? 163.465 136.071 142.239 1.00 64.89  ? 99  THR A O   1 
ATOM   88   C CB  . THR A 1 25  ? 164.569 133.202 142.308 1.00 66.36  ? 99  THR A CB  1 
ATOM   89   O OG1 . THR A 1 25  ? 164.419 131.777 142.350 1.00 66.98  ? 99  THR A OG1 1 
ATOM   90   C CG2 . THR A 1 25  ? 165.948 133.574 142.833 1.00 64.57  ? 99  THR A CG2 1 
ATOM   91   N N   . TRP A 1 26  ? 164.115 135.845 144.390 1.00 56.91  ? 100 TRP A N   1 
ATOM   92   C CA  . TRP A 1 26  ? 164.235 137.279 144.614 1.00 58.94  ? 100 TRP A CA  1 
ATOM   93   C C   . TRP A 1 26  ? 165.586 137.842 144.200 1.00 57.95  ? 100 TRP A C   1 
ATOM   94   O O   . TRP A 1 26  ? 165.661 139.015 143.814 1.00 60.70  ? 100 TRP A O   1 
ATOM   95   C CB  . TRP A 1 26  ? 163.985 137.603 146.089 1.00 58.37  ? 100 TRP A CB  1 
ATOM   96   C CG  . TRP A 1 26  ? 162.536 137.618 146.465 1.00 54.93  ? 100 TRP A CG  1 
ATOM   97   C CD1 . TRP A 1 26  ? 161.924 136.826 147.391 1.00 54.98  ? 100 TRP A CD1 1 
ATOM   98   C CD2 . TRP A 1 26  ? 161.516 138.471 145.931 1.00 48.04  ? 100 TRP A CD2 1 
ATOM   99   N NE1 . TRP A 1 26  ? 160.587 137.128 147.463 1.00 57.14  ? 100 TRP A NE1 1 
ATOM   100  C CE2 . TRP A 1 26  ? 160.312 138.135 146.577 1.00 53.06  ? 100 TRP A CE2 1 
ATOM   101  C CE3 . TRP A 1 26  ? 161.505 139.485 144.969 1.00 51.09  ? 100 TRP A CE3 1 
ATOM   102  C CZ2 . TRP A 1 26  ? 159.109 138.776 146.293 1.00 55.32  ? 100 TRP A CZ2 1 
ATOM   103  C CZ3 . TRP A 1 26  ? 160.310 140.119 144.689 1.00 54.49  ? 100 TRP A CZ3 1 
ATOM   104  C CH2 . TRP A 1 26  ? 159.130 139.762 145.347 1.00 55.02  ? 100 TRP A CH2 1 
ATOM   105  N N   . ASN A 1 27  ? 166.653 137.043 144.293 1.00 68.62  ? 101 ASN A N   1 
ATOM   106  C CA  . ASN A 1 27  ? 168.015 137.488 144.006 1.00 72.66  ? 101 ASN A CA  1 
ATOM   107  C C   . ASN A 1 27  ? 168.424 138.582 144.985 1.00 71.07  ? 101 ASN A C   1 
ATOM   108  O O   . ASN A 1 27  ? 169.272 138.361 145.855 1.00 69.37  ? 101 ASN A O   1 
ATOM   109  C CB  . ASN A 1 27  ? 168.149 137.969 142.557 1.00 71.70  ? 101 ASN A CB  1 
ATOM   110  C CG  . ASN A 1 27  ? 169.489 138.625 142.282 1.00 72.62  ? 101 ASN A CG  1 
ATOM   111  O OD1 . ASN A 1 27  ? 169.647 139.835 142.448 1.00 73.64  ? 101 ASN A OD1 1 
ATOM   112  N ND2 . ASN A 1 27  ? 170.463 137.828 141.858 1.00 69.46  ? 101 ASN A ND2 1 
ATOM   113  N N   . LYS A 1 28  ? 167.827 139.761 144.849 1.00 67.50  ? 102 LYS A N   1 
ATOM   114  C CA  . LYS A 1 28  ? 167.998 140.846 145.802 1.00 67.17  ? 102 LYS A CA  1 
ATOM   115  C C   . LYS A 1 28  ? 166.770 140.937 146.699 1.00 66.08  ? 102 LYS A C   1 
ATOM   116  O O   . LYS A 1 28  ? 165.643 140.684 146.266 1.00 65.77  ? 102 LYS A O   1 
ATOM   117  C CB  . LYS A 1 28  ? 168.234 142.174 145.080 1.00 66.83  ? 102 LYS A CB  1 
ATOM   118  C CG  . LYS A 1 28  ? 169.481 142.196 144.211 1.00 67.57  ? 102 LYS A CG  1 
ATOM   119  C CD  . LYS A 1 28  ? 170.740 142.034 145.045 1.00 68.63  ? 102 LYS A CD  1 
ATOM   120  C CE  . LYS A 1 28  ? 171.990 142.129 144.186 1.00 67.96  ? 102 LYS A CE  1 
ATOM   121  N NZ  . LYS A 1 28  ? 173.231 141.949 144.988 1.00 67.26  ? 102 LYS A NZ  1 
ATOM   122  N N   . SER A 1 29  ? 167.001 141.293 147.957 1.00 61.99  ? 103 SER A N   1 
ATOM   123  C CA  . SER A 1 29  ? 165.917 141.341 148.928 1.00 61.55  ? 103 SER A CA  1 
ATOM   124  C C   . SER A 1 29  ? 164.911 142.420 148.538 1.00 63.31  ? 103 SER A C   1 
ATOM   125  O O   . SER A 1 29  ? 165.306 143.568 148.289 1.00 64.49  ? 103 SER A O   1 
ATOM   126  C CB  . SER A 1 29  ? 166.464 141.611 150.328 1.00 60.30  ? 103 SER A CB  1 
ATOM   127  O OG  . SER A 1 29  ? 167.436 140.646 150.691 1.00 62.98  ? 103 SER A OG  1 
ATOM   128  N N   . PRO A 1 30  ? 163.620 142.099 148.463 1.00 49.07  ? 104 PRO A N   1 
ATOM   129  C CA  . PRO A 1 30  ? 162.630 143.116 148.096 1.00 43.12  ? 104 PRO A CA  1 
ATOM   130  C C   . PRO A 1 30  ? 162.539 144.213 149.146 1.00 43.04  ? 104 PRO A C   1 
ATOM   131  O O   . PRO A 1 30  ? 162.574 143.953 150.351 1.00 48.84  ? 104 PRO A O   1 
ATOM   132  C CB  . PRO A 1 30  ? 161.326 142.317 147.999 1.00 44.15  ? 104 PRO A CB  1 
ATOM   133  C CG  . PRO A 1 30  ? 161.550 141.147 148.900 1.00 44.69  ? 104 PRO A CG  1 
ATOM   134  C CD  . PRO A 1 30  ? 162.995 140.790 148.711 1.00 47.06  ? 104 PRO A CD  1 
ATOM   135  N N   . LYS A 1 31  ? 162.418 145.451 148.672 1.00 46.96  ? 105 LYS A N   1 
ATOM   136  C CA  . LYS A 1 31  ? 162.271 146.608 149.545 1.00 49.20  ? 105 LYS A CA  1 
ATOM   137  C C   . LYS A 1 31  ? 161.159 147.556 149.129 1.00 50.89  ? 105 LYS A C   1 
ATOM   138  O O   . LYS A 1 31  ? 160.696 148.334 149.972 1.00 56.91  ? 105 LYS A O   1 
ATOM   139  C CB  . LYS A 1 31  ? 163.592 147.376 149.612 1.00 53.15  ? 105 LYS A CB  1 
ATOM   140  C CG  . LYS A 1 31  ? 164.724 146.608 150.277 1.00 53.48  ? 105 LYS A CG  1 
ATOM   141  C CD  . LYS A 1 31  ? 166.010 147.417 150.288 1.00 54.32  ? 105 LYS A CD  1 
ATOM   142  C CE  . LYS A 1 31  ? 167.135 146.659 150.973 1.00 55.64  ? 105 LYS A CE  1 
ATOM   143  N NZ  . LYS A 1 31  ? 168.408 147.431 150.969 1.00 52.64  ? 105 LYS A NZ  1 
ATOM   144  N N   . SER A 1 32  ? 160.716 147.522 147.877 1.00 40.99  ? 106 SER A N   1 
ATOM   145  C CA  . SER A 1 32  ? 159.653 148.384 147.382 1.00 34.35  ? 106 SER A CA  1 
ATOM   146  C C   . SER A 1 32  ? 158.415 147.543 147.111 1.00 39.29  ? 106 SER A C   1 
ATOM   147  O O   . SER A 1 32  ? 158.483 146.547 146.384 1.00 48.75  ? 106 SER A O   1 
ATOM   148  C CB  . SER A 1 32  ? 160.091 149.110 146.110 1.00 43.51  ? 106 SER A CB  1 
ATOM   149  O OG  . SER A 1 32  ? 159.263 150.227 145.849 1.00 46.89  ? 106 SER A OG  1 
ATOM   150  N N   . VAL A 1 33  ? 157.288 147.947 147.689 1.00 26.77  ? 107 VAL A N   1 
ATOM   151  C CA  . VAL A 1 33  ? 156.034 147.217 147.563 1.00 22.35  ? 107 VAL A CA  1 
ATOM   152  C C   . VAL A 1 33  ? 154.924 148.199 147.217 1.00 30.31  ? 107 VAL A C   1 
ATOM   153  O O   . VAL A 1 33  ? 154.894 149.325 147.726 1.00 43.52  ? 107 VAL A O   1 
ATOM   154  C CB  . VAL A 1 33  ? 155.705 146.428 148.850 1.00 24.97  ? 107 VAL A CB  1 
ATOM   155  C CG1 . VAL A 1 33  ? 155.516 147.367 150.030 1.00 36.97  ? 107 VAL A CG1 1 
ATOM   156  C CG2 . VAL A 1 33  ? 154.474 145.560 148.649 1.00 34.76  ? 107 VAL A CG2 1 
ATOM   157  N N   . LEU A 1 34  ? 154.029 147.781 146.328 1.00 33.84  ? 108 LEU A N   1 
ATOM   158  C CA  . LEU A 1 34  ? 152.881 148.577 145.921 1.00 26.31  ? 108 LEU A CA  1 
ATOM   159  C C   . LEU A 1 34  ? 151.609 147.931 146.446 1.00 31.72  ? 108 LEU A C   1 
ATOM   160  O O   . LEU A 1 34  ? 151.376 146.739 146.222 1.00 42.49  ? 108 LEU A O   1 
ATOM   161  C CB  . LEU A 1 34  ? 152.810 148.703 144.399 1.00 32.30  ? 108 LEU A CB  1 
ATOM   162  C CG  . LEU A 1 34  ? 151.590 149.420 143.816 1.00 35.03  ? 108 LEU A CG  1 
ATOM   163  C CD1 . LEU A 1 34  ? 151.555 150.869 144.259 1.00 37.18  ? 108 LEU A CD1 1 
ATOM   164  C CD2 . LEU A 1 34  ? 151.573 149.321 142.300 1.00 36.19  ? 108 LEU A CD2 1 
ATOM   165  N N   . VAL A 1 35  ? 150.796 148.714 147.147 1.00 24.09  ? 109 VAL A N   1 
ATOM   166  C CA  . VAL A 1 35  ? 149.482 148.283 147.602 1.00 16.27  ? 109 VAL A CA  1 
ATOM   167  C C   . VAL A 1 35  ? 148.433 149.050 146.810 1.00 22.43  ? 109 VAL A C   1 
ATOM   168  O O   . VAL A 1 35  ? 148.472 150.285 146.741 1.00 35.52  ? 109 VAL A O   1 
ATOM   169  C CB  . VAL A 1 35  ? 149.311 148.475 149.120 1.00 18.27  ? 109 VAL A CB  1 
ATOM   170  C CG1 . VAL A 1 35  ? 150.237 147.536 149.869 1.00 27.62  ? 109 VAL A CG1 1 
ATOM   171  C CG2 . VAL A 1 35  ? 149.610 149.908 149.524 1.00 35.95  ? 109 VAL A CG2 1 
ATOM   172  N N   . ILE A 1 36  ? 147.518 148.318 146.183 1.00 32.56  ? 110 ILE A N   1 
ATOM   173  C CA  . ILE A 1 36  ? 146.481 148.901 145.342 1.00 29.44  ? 110 ILE A CA  1 
ATOM   174  C C   . ILE A 1 36  ? 145.137 148.605 145.988 1.00 34.63  ? 110 ILE A C   1 
ATOM   175  O O   . ILE A 1 36  ? 144.792 147.438 146.213 1.00 37.02  ? 110 ILE A O   1 
ATOM   176  C CB  . ILE A 1 36  ? 146.533 148.361 143.905 1.00 30.11  ? 110 ILE A CB  1 
ATOM   177  C CG1 . ILE A 1 36  ? 147.846 148.764 143.235 1.00 28.97  ? 110 ILE A CG1 1 
ATOM   178  C CG2 . ILE A 1 36  ? 145.366 148.898 143.101 1.00 37.52  ? 110 ILE A CG2 1 
ATOM   179  C CD1 . ILE A 1 36  ? 147.922 148.403 141.769 1.00 36.91  ? 110 ILE A CD1 1 
ATOM   180  N N   . LYS A 1 37  ? 144.385 149.657 146.284 1.00 40.41  ? 111 LYS A N   1 
ATOM   181  C CA  . LYS A 1 37  ? 143.098 149.553 146.951 1.00 40.57  ? 111 LYS A CA  1 
ATOM   182  C C   . LYS A 1 37  ? 141.977 149.672 145.921 1.00 44.08  ? 111 LYS A C   1 
ATOM   183  O O   . LYS A 1 37  ? 142.174 150.165 144.808 1.00 45.35  ? 111 LYS A O   1 
ATOM   184  C CB  . LYS A 1 37  ? 142.980 150.638 148.029 1.00 43.55  ? 111 LYS A CB  1 
ATOM   185  C CG  . LYS A 1 37  ? 141.720 150.602 148.878 1.00 44.28  ? 111 LYS A CG  1 
ATOM   186  C CD  . LYS A 1 37  ? 141.748 151.687 149.939 1.00 41.56  ? 111 LYS A CD  1 
ATOM   187  C CE  . LYS A 1 37  ? 140.537 151.599 150.849 1.00 45.24  ? 111 LYS A CE  1 
ATOM   188  N NZ  . LYS A 1 37  ? 139.280 151.926 150.123 1.00 47.18  ? 111 LYS A NZ  1 
ATOM   189  N N   . LYS A 1 38  ? 140.786 149.213 146.308 1.00 52.60  ? 112 LYS A N   1 
ATOM   190  C CA  . LYS A 1 38  ? 139.632 149.164 145.420 1.00 53.54  ? 112 LYS A CA  1 
ATOM   191  C C   . LYS A 1 38  ? 138.899 150.503 145.326 1.00 62.98  ? 112 LYS A C   1 
ATOM   192  O O   . LYS A 1 38  ? 137.705 150.521 144.998 1.00 62.94  ? 112 LYS A O   1 
ATOM   193  C CB  . LYS A 1 38  ? 138.670 148.063 145.877 1.00 53.62  ? 112 LYS A CB  1 
ATOM   194  C CG  . LYS A 1 38  ? 137.838 147.444 144.764 1.00 54.88  ? 112 LYS A CG  1 
ATOM   195  C CD  . LYS A 1 38  ? 136.527 146.895 145.301 1.00 57.15  ? 112 LYS A CD  1 
ATOM   196  C CE  . LYS A 1 38  ? 135.638 146.391 144.176 1.00 60.63  ? 112 LYS A CE  1 
ATOM   197  N NZ  . LYS A 1 38  ? 134.988 147.511 143.442 1.00 59.36  ? 112 LYS A NZ  1 
ATOM   198  N N   . MET A 1 39  ? 139.577 151.600 145.563 1.00 68.50  ? 113 MET A N   1 
ATOM   199  C CA  . MET A 1 39  ? 139.050 152.961 145.386 1.00 64.55  ? 113 MET A CA  1 
ATOM   200  C C   . MET A 1 39  ? 137.863 153.126 146.334 1.00 67.22  ? 113 MET A C   1 
ATOM   201  O O   . MET A 1 39  ? 138.031 152.930 147.549 1.00 67.53  ? 113 MET A O   1 
ATOM   202  C CB  . MET A 1 39  ? 138.758 153.206 143.910 1.00 64.11  ? 113 MET A CB  1 
ATOM   203  C CG  . MET A 1 39  ? 139.998 153.241 143.032 1.00 68.57  ? 113 MET A CG  1 
ATOM   204  S SD  . MET A 1 39  ? 139.614 153.517 141.293 1.00 79.58  ? 113 MET A SD  1 
ATOM   205  C CE  . MET A 1 39  ? 141.246 153.397 140.564 1.00 67.35  ? 113 MET A CE  1 
ATOM   206  N N   . ARG A 1 40  ? 136.687 153.461 145.872 1.00 71.91  ? 114 ARG A N   1 
ATOM   207  C CA  . ARG A 1 40  ? 135.502 153.768 146.669 1.00 70.74  ? 114 ARG A CA  1 
ATOM   208  C C   . ARG A 1 40  ? 135.017 152.498 147.354 1.00 68.14  ? 114 ARG A C   1 
ATOM   209  O O   . ARG A 1 40  ? 134.331 151.670 146.751 1.00 68.55  ? 114 ARG A O   1 
ATOM   210  C CB  . ARG A 1 40  ? 134.395 154.368 145.799 1.00 72.76  ? 114 ARG A CB  1 
ATOM   211  C CG  . ARG A 1 40  ? 134.715 155.751 145.255 1.00 72.02  ? 114 ARG A CG  1 
ATOM   212  C CD  . ARG A 1 40  ? 133.597 156.367 144.430 1.00 70.78  ? 114 ARG A CD  1 
ATOM   213  N NE  . ARG A 1 40  ? 133.977 157.662 143.874 1.00 73.06  ? 114 ARG A NE  1 
ATOM   214  C CZ  . ARG A 1 40  ? 133.231 158.356 143.026 1.00 72.78  ? 114 ARG A CZ  1 
ATOM   215  N NH1 . ARG A 1 40  ? 132.055 157.884 142.632 1.00 70.56  ? 114 ARG A NH1 1 
ATOM   216  N NH2 . ARG A 1 40  ? 133.657 159.527 142.569 1.00 73.25  ? 114 ARG A NH2 1 
ATOM   217  N N   . ASP A 1 41  ? 135.377 152.343 148.625 1.00 60.93  ? 115 ASP A N   1 
ATOM   218  C CA  . ASP A 1 41  ? 134.954 151.201 149.422 1.00 60.95  ? 115 ASP A CA  1 
ATOM   219  C C   . ASP A 1 41  ? 135.079 151.587 150.889 1.00 63.24  ? 115 ASP A C   1 
ATOM   220  O O   . ASP A 1 41  ? 135.717 152.583 151.235 1.00 62.66  ? 115 ASP A O   1 
ATOM   221  C CB  . ASP A 1 41  ? 135.780 149.951 149.097 1.00 62.99  ? 115 ASP A CB  1 
ATOM   222  C CG  . ASP A 1 41  ? 135.141 148.675 149.615 1.00 66.64  ? 115 ASP A CG  1 
ATOM   223  O OD1 . ASP A 1 41  ? 134.882 148.586 150.834 1.00 63.94  ? 115 ASP A OD1 1 
ATOM   224  O OD2 . ASP A 1 41  ? 134.896 147.760 148.801 1.00 66.73  ? 115 ASP A OD2 1 
ATOM   225  N N   . ALA A 1 42  ? 134.455 150.789 151.748 1.00 55.54  ? 116 ALA A N   1 
ATOM   226  C CA  . ALA A 1 42  ? 134.456 151.048 153.182 1.00 56.27  ? 116 ALA A CA  1 
ATOM   227  C C   . ALA A 1 42  ? 135.022 149.903 154.002 1.00 54.30  ? 116 ALA A C   1 
ATOM   228  O O   . ALA A 1 42  ? 135.716 150.146 154.993 1.00 56.96  ? 116 ALA A O   1 
ATOM   229  C CB  . ALA A 1 42  ? 133.031 151.361 153.663 1.00 57.88  ? 116 ALA A CB  1 
ATOM   230  N N   . SER A 1 43  ? 134.747 148.655 153.618 1.00 49.52  ? 117 SER A N   1 
ATOM   231  C CA  . SER A 1 43  ? 135.235 147.508 154.373 1.00 51.07  ? 117 SER A CA  1 
ATOM   232  C C   . SER A 1 43  ? 136.733 147.288 154.220 1.00 51.44  ? 117 SER A C   1 
ATOM   233  O O   . SER A 1 43  ? 137.298 146.471 154.954 1.00 52.99  ? 117 SER A O   1 
ATOM   234  C CB  . SER A 1 43  ? 134.486 146.244 153.947 1.00 51.11  ? 117 SER A CB  1 
ATOM   235  O OG  . SER A 1 43  ? 135.000 145.100 154.606 1.00 51.43  ? 117 SER A OG  1 
ATOM   236  N N   . LEU A 1 44  ? 137.385 147.986 153.293 1.00 47.93  ? 118 LEU A N   1 
ATOM   237  C CA  . LEU A 1 44  ? 138.798 147.770 153.020 1.00 43.57  ? 118 LEU A CA  1 
ATOM   238  C C   . LEU A 1 44  ? 139.716 148.735 153.757 1.00 48.30  ? 118 LEU A C   1 
ATOM   239  O O   . LEU A 1 44  ? 140.937 148.575 153.679 1.00 51.31  ? 118 LEU A O   1 
ATOM   240  C CB  . LEU A 1 44  ? 139.067 147.879 151.516 1.00 46.07  ? 118 LEU A CB  1 
ATOM   241  C CG  . LEU A 1 44  ? 139.091 146.586 150.701 1.00 43.81  ? 118 LEU A CG  1 
ATOM   242  C CD1 . LEU A 1 44  ? 137.801 145.800 150.871 1.00 46.60  ? 118 LEU A CD1 1 
ATOM   243  C CD2 . LEU A 1 44  ? 139.340 146.903 149.242 1.00 44.02  ? 118 LEU A CD2 1 
ATOM   244  N N   . LEU A 1 45  ? 139.170 149.725 154.467 1.00 50.51  ? 119 LEU A N   1 
ATOM   245  C CA  . LEU A 1 45  ? 140.021 150.720 155.116 1.00 40.41  ? 119 LEU A CA  1 
ATOM   246  C C   . LEU A 1 45  ? 140.828 150.106 156.253 1.00 44.42  ? 119 LEU A C   1 
ATOM   247  O O   . LEU A 1 45  ? 142.040 150.327 156.355 1.00 49.10  ? 119 LEU A O   1 
ATOM   248  C CB  . LEU A 1 45  ? 139.180 151.892 155.626 1.00 39.71  ? 119 LEU A CB  1 
ATOM   249  C CG  . LEU A 1 45  ? 138.803 153.006 154.644 1.00 50.94  ? 119 LEU A CG  1 
ATOM   250  C CD1 . LEU A 1 45  ? 140.052 153.726 154.154 1.00 47.26  ? 119 LEU A CD1 1 
ATOM   251  C CD2 . LEU A 1 45  ? 137.981 152.492 153.473 1.00 50.08  ? 119 LEU A CD2 1 
ATOM   252  N N   . GLN A 1 46  ? 140.172 149.339 157.122 1.00 44.07  ? 120 GLN A N   1 
ATOM   253  C CA  . GLN A 1 46  ? 140.889 148.706 158.228 1.00 43.66  ? 120 GLN A CA  1 
ATOM   254  C C   . GLN A 1 46  ? 141.945 147.717 157.752 1.00 42.56  ? 120 GLN A C   1 
ATOM   255  O O   . GLN A 1 46  ? 143.086 147.787 158.242 1.00 50.64  ? 120 GLN A O   1 
ATOM   256  C CB  . GLN A 1 46  ? 139.887 148.049 159.185 1.00 44.00  ? 120 GLN A CB  1 
ATOM   257  C CG  . GLN A 1 46  ? 140.511 147.458 160.442 1.00 48.06  ? 120 GLN A CG  1 
ATOM   258  C CD  . GLN A 1 46  ? 141.245 148.486 161.284 1.00 50.72  ? 120 GLN A CD  1 
ATOM   259  O OE1 . GLN A 1 46  ? 140.967 149.683 161.212 1.00 50.14  ? 120 GLN A OE1 1 
ATOM   260  N NE2 . GLN A 1 46  ? 142.191 148.018 162.091 1.00 47.73  ? 120 GLN A NE2 1 
ATOM   261  N N   . PRO A 1 47  ? 141.657 146.779 156.838 1.00 39.78  ? 121 PRO A N   1 
ATOM   262  C CA  . PRO A 1 47  ? 142.737 145.908 156.349 1.00 41.13  ? 121 PRO A CA  1 
ATOM   263  C C   . PRO A 1 47  ? 143.843 146.661 155.632 1.00 36.52  ? 121 PRO A C   1 
ATOM   264  O O   . PRO A 1 47  ? 145.017 146.295 155.764 1.00 44.82  ? 121 PRO A O   1 
ATOM   265  C CB  . PRO A 1 47  ? 142.001 144.945 155.411 1.00 39.38  ? 121 PRO A CB  1 
ATOM   266  C CG  . PRO A 1 47  ? 140.602 144.949 155.902 1.00 40.07  ? 121 PRO A CG  1 
ATOM   267  C CD  . PRO A 1 47  ? 140.358 146.371 156.275 1.00 42.20  ? 121 PRO A CD  1 
ATOM   268  N N   . PHE A 1 48  ? 143.502 147.705 154.874 1.00 29.40  ? 122 PHE A N   1 
ATOM   269  C CA  . PHE A 1 48  ? 144.525 148.511 154.214 1.00 29.62  ? 122 PHE A CA  1 
ATOM   270  C C   . PHE A 1 48  ? 145.448 149.156 155.236 1.00 42.40  ? 122 PHE A C   1 
ATOM   271  O O   . PHE A 1 48  ? 146.677 149.120 155.095 1.00 51.44  ? 122 PHE A O   1 
ATOM   272  C CB  . PHE A 1 48  ? 143.863 149.577 153.341 1.00 36.96  ? 122 PHE A CB  1 
ATOM   273  C CG  . PHE A 1 48  ? 144.830 150.527 152.695 1.00 35.08  ? 122 PHE A CG  1 
ATOM   274  C CD1 . PHE A 1 48  ? 145.756 150.076 151.773 1.00 38.58  ? 122 PHE A CD1 1 
ATOM   275  C CD2 . PHE A 1 48  ? 144.813 151.873 153.016 1.00 38.30  ? 122 PHE A CD2 1 
ATOM   276  C CE1 . PHE A 1 48  ? 146.642 150.951 151.178 1.00 36.56  ? 122 PHE A CE1 1 
ATOM   277  C CE2 . PHE A 1 48  ? 145.700 152.751 152.427 1.00 34.57  ? 122 PHE A CE2 1 
ATOM   278  C CZ  . PHE A 1 48  ? 146.615 152.289 151.508 1.00 36.53  ? 122 PHE A CZ  1 
ATOM   279  N N   . LYS A 1 49  ? 144.866 149.744 156.283 1.00 48.36  ? 123 LYS A N   1 
ATOM   280  C CA  . LYS A 1 49  ? 145.668 150.364 157.331 1.00 43.26  ? 123 LYS A CA  1 
ATOM   281  C C   . LYS A 1 49  ? 146.541 149.336 158.036 1.00 43.23  ? 123 LYS A C   1 
ATOM   282  O O   . LYS A 1 49  ? 147.724 149.588 158.289 1.00 51.95  ? 123 LYS A O   1 
ATOM   283  C CB  . LYS A 1 49  ? 144.758 151.071 158.334 1.00 48.56  ? 123 LYS A CB  1 
ATOM   284  C CG  . LYS A 1 49  ? 144.232 152.413 157.860 1.00 51.57  ? 123 LYS A CG  1 
ATOM   285  C CD  . LYS A 1 49  ? 143.224 152.982 158.841 1.00 52.07  ? 123 LYS A CD  1 
ATOM   286  C CE  . LYS A 1 49  ? 142.099 153.702 158.118 1.00 52.47  ? 123 LYS A CE  1 
ATOM   287  N NZ  . LYS A 1 49  ? 140.841 153.701 158.913 1.00 52.11  ? 123 LYS A NZ  1 
ATOM   288  N N   . GLU A 1 50  ? 145.975 148.172 158.363 1.00 32.65  ? 124 GLU A N   1 
ATOM   289  C CA  . GLU A 1 50  ? 146.748 147.145 159.053 1.00 28.23  ? 124 GLU A CA  1 
ATOM   290  C C   . GLU A 1 50  ? 147.914 146.665 158.198 1.00 39.53  ? 124 GLU A C   1 
ATOM   291  O O   . GLU A 1 50  ? 149.041 146.527 158.690 1.00 49.11  ? 124 GLU A O   1 
ATOM   292  C CB  . GLU A 1 50  ? 145.841 145.975 159.432 1.00 36.33  ? 124 GLU A CB  1 
ATOM   293  C CG  . GLU A 1 50  ? 146.428 145.044 160.476 1.00 45.22  ? 124 GLU A CG  1 
ATOM   294  C CD  . GLU A 1 50  ? 145.411 144.053 161.009 1.00 50.71  ? 124 GLU A CD  1 
ATOM   295  O OE1 . GLU A 1 50  ? 144.205 144.378 161.009 1.00 51.01  ? 124 GLU A OE1 1 
ATOM   296  O OE2 . GLU A 1 50  ? 145.818 142.949 161.429 1.00 52.63  ? 124 GLU A OE2 1 
ATOM   297  N N   . LEU A 1 51  ? 147.664 146.419 156.910 1.00 44.07  ? 125 LEU A N   1 
ATOM   298  C CA  . LEU A 1 51  ? 148.724 145.963 156.019 1.00 38.56  ? 125 LEU A CA  1 
ATOM   299  C C   . LEU A 1 51  ? 149.802 147.025 155.854 1.00 34.03  ? 125 LEU A C   1 
ATOM   300  O O   . LEU A 1 51  ? 150.996 146.707 155.835 1.00 40.73  ? 125 LEU A O   1 
ATOM   301  C CB  . LEU A 1 51  ? 148.136 145.576 154.662 1.00 40.76  ? 125 LEU A CB  1 
ATOM   302  C CG  . LEU A 1 51  ? 149.130 145.178 153.571 1.00 40.00  ? 125 LEU A CG  1 
ATOM   303  C CD1 . LEU A 1 51  ? 149.719 143.808 153.858 1.00 36.95  ? 125 LEU A CD1 1 
ATOM   304  C CD2 . LEU A 1 51  ? 148.461 145.201 152.208 1.00 41.42  ? 125 LEU A CD2 1 
ATOM   305  N N   . CYS A 1 52  ? 149.405 148.294 155.733 1.00 37.36  ? 126 CYS A N   1 
ATOM   306  C CA  . CYS A 1 52  ? 150.393 149.356 155.578 1.00 41.51  ? 126 CYS A CA  1 
ATOM   307  C C   . CYS A 1 52  ? 151.238 149.522 156.835 1.00 46.90  ? 126 CYS A C   1 
ATOM   308  O O   . CYS A 1 52  ? 152.455 149.722 156.746 1.00 51.62  ? 126 CYS A O   1 
ATOM   309  C CB  . CYS A 1 52  ? 149.701 150.668 155.215 1.00 45.87  ? 126 CYS A CB  1 
ATOM   310  S SG  . CYS A 1 52  ? 149.182 150.765 153.491 1.00 61.86  ? 126 CYS A SG  1 
ATOM   311  N N   . THR A 1 53  ? 150.615 149.448 158.014 1.00 43.43  ? 127 THR A N   1 
ATOM   312  C CA  . THR A 1 53  ? 151.384 149.541 159.252 1.00 37.14  ? 127 THR A CA  1 
ATOM   313  C C   . THR A 1 53  ? 152.329 148.357 159.408 1.00 37.37  ? 127 THR A C   1 
ATOM   314  O O   . THR A 1 53  ? 153.468 148.524 159.858 1.00 47.53  ? 127 THR A O   1 
ATOM   315  C CB  . THR A 1 53  ? 150.454 149.644 160.462 1.00 43.88  ? 127 THR A CB  1 
ATOM   316  O OG1 . THR A 1 53  ? 149.633 148.472 160.545 1.00 46.31  ? 127 THR A OG1 1 
ATOM   317  C CG2 . THR A 1 53  ? 149.583 150.890 160.376 1.00 47.28  ? 127 THR A CG2 1 
ATOM   318  N N   . HIS A 1 54  ? 151.879 147.152 159.049 1.00 39.15  ? 128 HIS A N   1 
ATOM   319  C CA  . HIS A 1 54  ? 152.751 145.991 159.178 1.00 36.99  ? 128 HIS A CA  1 
ATOM   320  C C   . HIS A 1 54  ? 153.891 146.018 158.169 1.00 37.55  ? 128 HIS A C   1 
ATOM   321  O O   . HIS A 1 54  ? 154.994 145.559 158.478 1.00 43.67  ? 128 HIS A O   1 
ATOM   322  C CB  . HIS A 1 54  ? 151.950 144.699 159.028 1.00 32.27  ? 128 HIS A CB  1 
ATOM   323  C CG  . HIS A 1 54  ? 152.803 143.485 158.824 1.00 36.42  ? 128 HIS A CG  1 
ATOM   324  N ND1 . HIS A 1 54  ? 153.255 143.091 157.584 1.00 44.74  ? 128 HIS A ND1 1 
ATOM   325  C CD2 . HIS A 1 54  ? 153.308 142.594 159.709 1.00 40.96  ? 128 HIS A CD2 1 
ATOM   326  C CE1 . HIS A 1 54  ? 153.989 142.000 157.711 1.00 40.54  ? 128 HIS A CE1 1 
ATOM   327  N NE2 . HIS A 1 54  ? 154.037 141.678 158.990 1.00 36.78  ? 128 HIS A NE2 1 
ATOM   328  N N   . LEU A 1 55  ? 153.651 146.541 156.965 1.00 43.58  ? 129 LEU A N   1 
ATOM   329  C CA  . LEU A 1 55  ? 154.661 146.465 155.914 1.00 40.87  ? 129 LEU A CA  1 
ATOM   330  C C   . LEU A 1 55  ? 155.909 147.260 156.276 1.00 43.67  ? 129 LEU A C   1 
ATOM   331  O O   . LEU A 1 55  ? 157.027 146.862 155.931 1.00 52.63  ? 129 LEU A O   1 
ATOM   332  C CB  . LEU A 1 55  ? 154.078 146.954 154.589 1.00 43.23  ? 129 LEU A CB  1 
ATOM   333  C CG  . LEU A 1 55  ? 153.314 145.909 153.773 1.00 41.79  ? 129 LEU A CG  1 
ATOM   334  C CD1 . LEU A 1 55  ? 152.935 146.454 152.408 1.00 45.18  ? 129 LEU A CD1 1 
ATOM   335  C CD2 . LEU A 1 55  ? 154.129 144.633 153.636 1.00 43.50  ? 129 LEU A CD2 1 
ATOM   336  N N   . MET A 1 56  ? 155.745 148.380 156.974 1.00 48.62  ? 130 MET A N   1 
ATOM   337  C CA  . MET A 1 56  ? 156.867 149.250 157.295 1.00 50.92  ? 130 MET A CA  1 
ATOM   338  C C   . MET A 1 56  ? 157.488 148.964 158.656 1.00 49.46  ? 130 MET A C   1 
ATOM   339  O O   . MET A 1 56  ? 158.329 149.747 159.111 1.00 53.97  ? 130 MET A O   1 
ATOM   340  C CB  . MET A 1 56  ? 156.443 150.717 157.203 1.00 45.59  ? 130 MET A CB  1 
ATOM   341  C CG  . MET A 1 56  ? 156.106 151.142 155.788 1.00 50.20  ? 130 MET A CG  1 
ATOM   342  S SD  . MET A 1 56  ? 155.665 152.876 155.634 1.00 59.24  ? 130 MET A SD  1 
ATOM   343  C CE  . MET A 1 56  ? 154.032 152.850 156.350 1.00 52.75  ? 130 MET A CE  1 
ATOM   344  N N   . GLU A 1 57  ? 157.106 147.874 159.316 1.00 46.59  ? 131 GLU A N   1 
ATOM   345  C CA  . GLU A 1 57  ? 157.858 147.413 160.474 1.00 44.93  ? 131 GLU A CA  1 
ATOM   346  C C   . GLU A 1 57  ? 158.979 146.458 160.085 1.00 50.75  ? 131 GLU A C   1 
ATOM   347  O O   . GLU A 1 57  ? 159.763 146.056 160.952 1.00 57.63  ? 131 GLU A O   1 
ATOM   348  C CB  . GLU A 1 57  ? 156.931 146.752 161.502 1.00 45.95  ? 131 GLU A CB  1 
ATOM   349  C CG  . GLU A 1 57  ? 156.514 145.331 161.177 1.00 51.59  ? 131 GLU A CG  1 
ATOM   350  C CD  . GLU A 1 57  ? 155.508 144.783 162.172 1.00 56.17  ? 131 GLU A CD  1 
ATOM   351  O OE1 . GLU A 1 57  ? 154.624 145.550 162.609 1.00 58.51  ? 131 GLU A OE1 1 
ATOM   352  O OE2 . GLU A 1 57  ? 155.600 143.586 162.516 1.00 54.46  ? 131 GLU A OE2 1 
ATOM   353  N N   . GLU A 1 58  ? 159.070 146.086 158.806 1.00 44.12  ? 132 GLU A N   1 
ATOM   354  C CA  . GLU A 1 58  ? 160.246 145.429 158.251 1.00 47.68  ? 132 GLU A CA  1 
ATOM   355  C C   . GLU A 1 58  ? 161.031 146.358 157.330 1.00 49.37  ? 132 GLU A C   1 
ATOM   356  O O   . GLU A 1 58  ? 161.845 145.888 156.529 1.00 53.59  ? 132 GLU A O   1 
ATOM   357  C CB  . GLU A 1 58  ? 159.864 144.151 157.501 1.00 47.58  ? 132 GLU A CB  1 
ATOM   358  C CG  . GLU A 1 58  ? 159.317 143.035 158.376 1.00 49.28  ? 132 GLU A CG  1 
ATOM   359  C CD  . GLU A 1 58  ? 157.845 143.200 158.674 1.00 52.10  ? 132 GLU A CD  1 
ATOM   360  O OE1 . GLU A 1 58  ? 157.243 144.153 158.143 1.00 53.07  ? 132 GLU A OE1 1 
ATOM   361  O OE2 . GLU A 1 58  ? 157.292 142.380 159.436 1.00 51.53  ? 132 GLU A OE2 1 
ATOM   362  N N   . ASN A 1 59  ? 160.792 147.667 157.429 1.00 50.88  ? 133 ASN A N   1 
ATOM   363  C CA  . ASN A 1 59  ? 161.493 148.681 156.642 1.00 53.70  ? 133 ASN A CA  1 
ATOM   364  C C   . ASN A 1 59  ? 161.307 148.444 155.141 1.00 55.05  ? 133 ASN A C   1 
ATOM   365  O O   . ASN A 1 59  ? 162.265 148.336 154.373 1.00 60.31  ? 133 ASN A O   1 
ATOM   366  C CB  . ASN A 1 59  ? 162.978 148.734 157.018 1.00 55.34  ? 133 ASN A CB  1 
ATOM   367  C CG  . ASN A 1 59  ? 163.611 150.077 156.713 1.00 57.38  ? 133 ASN A CG  1 
ATOM   368  O OD1 . ASN A 1 59  ? 163.188 150.782 155.797 1.00 57.74  ? 133 ASN A OD1 1 
ATOM   369  N ND2 . ASN A 1 59  ? 164.630 150.439 157.484 1.00 56.63  ? 133 ASN A ND2 1 
ATOM   370  N N   . MET A 1 60  ? 160.043 148.363 154.736 1.00 51.80  ? 134 MET A N   1 
ATOM   371  C CA  . MET A 1 60  ? 159.665 148.203 153.338 1.00 48.70  ? 134 MET A CA  1 
ATOM   372  C C   . MET A 1 60  ? 159.101 149.514 152.811 1.00 49.70  ? 134 MET A C   1 
ATOM   373  O O   . MET A 1 60  ? 158.238 150.125 153.450 1.00 56.97  ? 134 MET A O   1 
ATOM   374  C CB  . MET A 1 60  ? 158.635 147.086 153.170 1.00 52.36  ? 134 MET A CB  1 
ATOM   375  C CG  . MET A 1 60  ? 159.159 145.700 153.484 1.00 52.54  ? 134 MET A CG  1 
ATOM   376  S SD  . MET A 1 60  ? 157.874 144.447 153.346 1.00 66.52  ? 134 MET A SD  1 
ATOM   377  C CE  . MET A 1 60  ? 157.625 144.407 151.574 1.00 55.38  ? 134 MET A CE  1 
ATOM   378  N N   . ILE A 1 61  ? 159.589 149.943 151.652 1.00 39.89  ? 135 ILE A N   1 
ATOM   379  C CA  . ILE A 1 61  ? 159.071 151.140 151.000 1.00 39.82  ? 135 ILE A CA  1 
ATOM   380  C C   . ILE A 1 61  ? 157.720 150.801 150.384 1.00 47.33  ? 135 ILE A C   1 
ATOM   381  O O   . ILE A 1 61  ? 157.609 149.865 149.585 1.00 52.83  ? 135 ILE A O   1 
ATOM   382  C CB  . ILE A 1 61  ? 160.050 151.661 149.940 1.00 38.76  ? 135 ILE A CB  1 
ATOM   383  C CG1 . ILE A 1 61  ? 161.482 151.625 150.477 1.00 45.85  ? 135 ILE A CG1 1 
ATOM   384  C CG2 . ILE A 1 61  ? 159.676 153.070 149.519 1.00 41.14  ? 135 ILE A CG2 1 
ATOM   385  C CD1 . ILE A 1 61  ? 162.541 151.776 149.406 1.00 46.79  ? 135 ILE A CD1 1 
ATOM   386  N N   . VAL A 1 62  ? 156.691 151.560 150.751 1.00 32.68  ? 136 VAL A N   1 
ATOM   387  C CA  . VAL A 1 62  ? 155.320 151.284 150.341 1.00 24.13  ? 136 VAL A CA  1 
ATOM   388  C C   . VAL A 1 62  ? 154.844 152.406 149.430 1.00 33.56  ? 136 VAL A C   1 
ATOM   389  O O   . VAL A 1 62  ? 154.970 153.588 149.770 1.00 43.43  ? 136 VAL A O   1 
ATOM   390  C CB  . VAL A 1 62  ? 154.387 151.127 151.553 1.00 29.55  ? 136 VAL A CB  1 
ATOM   391  C CG1 . VAL A 1 62  ? 153.010 150.673 151.102 1.00 37.16  ? 136 VAL A CG1 1 
ATOM   392  C CG2 . VAL A 1 62  ? 154.973 150.136 152.538 1.00 36.24  ? 136 VAL A CG2 1 
ATOM   393  N N   . TYR A 1 63  ? 154.299 152.031 148.278 1.00 37.80  ? 137 TYR A N   1 
ATOM   394  C CA  . TYR A 1 63  ? 153.769 152.970 147.302 1.00 33.07  ? 137 TYR A CA  1 
ATOM   395  C C   . TYR A 1 63  ? 152.249 152.897 147.296 1.00 37.29  ? 137 TYR A C   1 
ATOM   396  O O   . TYR A 1 63  ? 151.670 151.807 147.331 1.00 46.96  ? 137 TYR A O   1 
ATOM   397  C CB  . TYR A 1 63  ? 154.315 152.675 145.902 1.00 40.83  ? 137 TYR A CB  1 
ATOM   398  C CG  . TYR A 1 63  ? 155.739 153.133 145.687 1.00 39.40  ? 137 TYR A CG  1 
ATOM   399  C CD1 . TYR A 1 63  ? 156.783 152.589 146.422 1.00 40.86  ? 137 TYR A CD1 1 
ATOM   400  C CD2 . TYR A 1 63  ? 156.041 154.104 144.742 1.00 42.80  ? 137 TYR A CD2 1 
ATOM   401  C CE1 . TYR A 1 63  ? 158.083 153.005 146.229 1.00 41.45  ? 137 TYR A CE1 1 
ATOM   402  C CE2 . TYR A 1 63  ? 157.341 154.523 144.539 1.00 43.10  ? 137 TYR A CE2 1 
ATOM   403  C CZ  . TYR A 1 63  ? 158.358 153.969 145.286 1.00 41.99  ? 137 TYR A CZ  1 
ATOM   404  O OH  . TYR A 1 63  ? 159.656 154.382 145.092 1.00 42.25  ? 137 TYR A OH  1 
ATOM   405  N N   . VAL A 1 64  ? 151.609 154.062 147.269 1.00 40.72  ? 138 VAL A N   1 
ATOM   406  C CA  . VAL A 1 64  ? 150.155 154.168 147.294 1.00 40.52  ? 138 VAL A CA  1 
ATOM   407  C C   . VAL A 1 64  ? 149.733 155.181 146.238 1.00 49.95  ? 138 VAL A C   1 
ATOM   408  O O   . VAL A 1 64  ? 150.424 156.180 146.013 1.00 56.24  ? 138 VAL A O   1 
ATOM   409  C CB  . VAL A 1 64  ? 149.641 154.578 148.692 1.00 48.94  ? 138 VAL A CB  1 
ATOM   410  C CG1 . VAL A 1 64  ? 148.132 154.767 148.687 1.00 53.27  ? 138 VAL A CG1 1 
ATOM   411  C CG2 . VAL A 1 64  ? 150.042 153.550 149.739 1.00 50.69  ? 138 VAL A CG2 1 
ATOM   412  N N   . GLU A 1 65  ? 148.607 154.913 145.580 1.00 65.81  ? 139 GLU A N   1 
ATOM   413  C CA  . GLU A 1 65  ? 148.039 155.875 144.645 1.00 69.90  ? 139 GLU A CA  1 
ATOM   414  C C   . GLU A 1 65  ? 147.726 157.188 145.354 1.00 75.95  ? 139 GLU A C   1 
ATOM   415  O O   . GLU A 1 65  ? 147.291 157.201 146.509 1.00 74.95  ? 139 GLU A O   1 
ATOM   416  C CB  . GLU A 1 65  ? 146.772 155.301 144.005 1.00 70.89  ? 139 GLU A CB  1 
ATOM   417  C CG  . GLU A 1 65  ? 146.014 156.278 143.116 1.00 72.91  ? 139 GLU A CG  1 
ATOM   418  C CD  . GLU A 1 65  ? 146.800 156.692 141.888 1.00 74.75  ? 139 GLU A CD  1 
ATOM   419  O OE1 . GLU A 1 65  ? 147.633 155.892 141.413 1.00 74.35  ? 139 GLU A OE1 1 
ATOM   420  O OE2 . GLU A 1 65  ? 146.590 157.823 141.403 1.00 72.90  ? 139 GLU A OE2 1 
ATOM   421  N N   . LYS A 1 66  ? 147.961 158.300 144.652 1.00 76.02  ? 140 LYS A N   1 
ATOM   422  C CA  . LYS A 1 66  ? 147.738 159.617 145.242 1.00 70.40  ? 140 LYS A CA  1 
ATOM   423  C C   . LYS A 1 66  ? 146.274 159.814 145.616 1.00 70.92  ? 140 LYS A C   1 
ATOM   424  O O   . LYS A 1 66  ? 145.967 160.388 146.668 1.00 74.28  ? 140 LYS A O   1 
ATOM   425  C CB  . LYS A 1 66  ? 148.205 160.707 144.275 1.00 71.55  ? 140 LYS A CB  1 
ATOM   426  C CG  . LYS A 1 66  ? 148.231 162.117 144.858 1.00 76.20  ? 140 LYS A CG  1 
ATOM   427  C CD  . LYS A 1 66  ? 146.951 162.886 144.564 1.00 76.22  ? 140 LYS A CD  1 
ATOM   428  C CE  . LYS A 1 66  ? 147.034 164.311 145.085 1.00 74.44  ? 140 LYS A CE  1 
ATOM   429  N NZ  . LYS A 1 66  ? 145.777 165.069 144.838 1.00 74.71  ? 140 LYS A NZ  1 
ATOM   430  N N   . LYS A 1 67  ? 145.356 159.350 144.765 1.00 72.33  ? 141 LYS A N   1 
ATOM   431  C CA  . LYS A 1 67  ? 143.934 159.504 145.048 1.00 73.06  ? 141 LYS A CA  1 
ATOM   432  C C   . LYS A 1 67  ? 143.500 158.730 146.286 1.00 74.42  ? 141 LYS A C   1 
ATOM   433  O O   . LYS A 1 67  ? 142.479 159.074 146.891 1.00 76.62  ? 141 LYS A O   1 
ATOM   434  C CB  . LYS A 1 67  ? 143.108 159.063 143.839 1.00 74.95  ? 141 LYS A CB  1 
ATOM   435  C CG  . LYS A 1 67  ? 143.256 159.967 142.626 1.00 75.96  ? 141 LYS A CG  1 
ATOM   436  C CD  . LYS A 1 67  ? 142.386 159.494 141.473 1.00 76.83  ? 141 LYS A CD  1 
ATOM   437  C CE  . LYS A 1 67  ? 142.553 160.388 140.255 1.00 76.33  ? 141 LYS A CE  1 
ATOM   438  N NZ  . LYS A 1 67  ? 141.717 159.930 139.111 1.00 75.70  ? 141 LYS A NZ  1 
ATOM   439  N N   . VAL A 1 68  ? 144.240 157.688 146.670 1.00 69.85  ? 142 VAL A N   1 
ATOM   440  C CA  . VAL A 1 68  ? 143.897 156.948 147.880 1.00 71.85  ? 142 VAL A CA  1 
ATOM   441  C C   . VAL A 1 68  ? 144.188 157.784 149.120 1.00 73.56  ? 142 VAL A C   1 
ATOM   442  O O   . VAL A 1 68  ? 143.395 157.809 150.069 1.00 74.65  ? 142 VAL A O   1 
ATOM   443  C CB  . VAL A 1 68  ? 144.643 155.602 147.911 1.00 72.05  ? 142 VAL A CB  1 
ATOM   444  C CG1 . VAL A 1 68  ? 144.367 154.868 149.214 1.00 70.94  ? 142 VAL A CG1 1 
ATOM   445  C CG2 . VAL A 1 68  ? 144.244 154.748 146.719 1.00 71.75  ? 142 VAL A CG2 1 
ATOM   446  N N   . LEU A 1 69  ? 145.323 158.487 149.132 1.00 70.11  ? 143 LEU A N   1 
ATOM   447  C CA  . LEU A 1 69  ? 145.712 159.277 150.294 1.00 69.93  ? 143 LEU A CA  1 
ATOM   448  C C   . LEU A 1 69  ? 144.895 160.553 150.454 1.00 72.20  ? 143 LEU A C   1 
ATOM   449  O O   . LEU A 1 69  ? 144.981 161.190 151.509 1.00 72.57  ? 143 LEU A O   1 
ATOM   450  C CB  . LEU A 1 69  ? 147.199 159.624 150.219 1.00 68.42  ? 143 LEU A CB  1 
ATOM   451  C CG  . LEU A 1 69  ? 148.150 158.437 150.375 1.00 70.33  ? 143 LEU A CG  1 
ATOM   452  C CD1 . LEU A 1 69  ? 149.594 158.906 150.413 1.00 70.25  ? 143 LEU A CD1 1 
ATOM   453  C CD2 . LEU A 1 69  ? 147.806 157.642 151.625 1.00 70.29  ? 143 LEU A CD2 1 
ATOM   454  N N   . GLU A 1 70  ? 144.121 160.949 149.445 1.00 71.99  ? 144 GLU A N   1 
ATOM   455  C CA  . GLU A 1 70  ? 143.236 162.099 149.554 1.00 68.62  ? 144 GLU A CA  1 
ATOM   456  C C   . GLU A 1 70  ? 141.803 161.698 149.876 1.00 69.91  ? 144 GLU A C   1 
ATOM   457  O O   . GLU A 1 70  ? 140.901 162.537 149.796 1.00 71.80  ? 144 GLU A O   1 
ATOM   458  C CB  . GLU A 1 70  ? 143.276 162.930 148.269 1.00 70.88  ? 144 GLU A CB  1 
ATOM   459  C CG  . GLU A 1 70  ? 142.674 162.245 147.058 1.00 74.36  ? 144 GLU A CG  1 
ATOM   460  C CD  . GLU A 1 70  ? 142.792 163.080 145.799 1.00 76.93  ? 144 GLU A CD  1 
ATOM   461  O OE1 . GLU A 1 70  ? 143.366 164.187 145.870 1.00 78.11  ? 144 GLU A OE1 1 
ATOM   462  O OE2 . GLU A 1 70  ? 142.313 162.629 144.737 1.00 76.84  ? 144 GLU A OE2 1 
ATOM   463  N N   . ASP A 1 71  ? 141.577 160.437 150.229 1.00 69.84  ? 145 ASP A N   1 
ATOM   464  C CA  . ASP A 1 71  ? 140.247 159.997 150.619 1.00 71.62  ? 145 ASP A CA  1 
ATOM   465  C C   . ASP A 1 71  ? 139.822 160.716 151.897 1.00 71.88  ? 145 ASP A C   1 
ATOM   466  O O   . ASP A 1 71  ? 140.659 160.973 152.771 1.00 71.61  ? 145 ASP A O   1 
ATOM   467  C CB  . ASP A 1 71  ? 140.231 158.483 150.834 1.00 73.74  ? 145 ASP A CB  1 
ATOM   468  C CG  . ASP A 1 71  ? 138.842 157.944 151.108 1.00 75.31  ? 145 ASP A CG  1 
ATOM   469  O OD1 . ASP A 1 71  ? 138.036 157.860 150.157 1.00 74.09  ? 145 ASP A OD1 1 
ATOM   470  O OD2 . ASP A 1 71  ? 138.555 157.604 152.275 1.00 75.11  ? 145 ASP A OD2 1 
ATOM   471  N N   . PRO A 1 72  ? 138.544 161.082 152.030 1.00 75.83  ? 146 PRO A N   1 
ATOM   472  C CA  . PRO A 1 72  ? 138.114 161.752 153.269 1.00 75.59  ? 146 PRO A CA  1 
ATOM   473  C C   . PRO A 1 72  ? 138.369 160.933 154.522 1.00 72.77  ? 146 PRO A C   1 
ATOM   474  O O   . PRO A 1 72  ? 138.775 161.493 155.547 1.00 74.62  ? 146 PRO A O   1 
ATOM   475  C CB  . PRO A 1 72  ? 136.612 161.988 153.035 1.00 74.99  ? 146 PRO A CB  1 
ATOM   476  C CG  . PRO A 1 72  ? 136.240 161.076 151.899 1.00 74.85  ? 146 PRO A CG  1 
ATOM   477  C CD  . PRO A 1 72  ? 137.458 161.009 151.041 1.00 76.04  ? 146 PRO A CD  1 
ATOM   478  N N   . ALA A 1 73  ? 138.144 159.623 154.473 1.00 64.49  ? 147 ALA A N   1 
ATOM   479  C CA  . ALA A 1 73  ? 138.360 158.770 155.642 1.00 65.98  ? 147 ALA A CA  1 
ATOM   480  C C   . ALA A 1 73  ? 139.743 158.125 155.638 1.00 65.21  ? 147 ALA A C   1 
ATOM   481  O O   . ALA A 1 73  ? 139.882 156.918 155.828 1.00 65.34  ? 147 ALA A O   1 
ATOM   482  C CB  . ALA A 1 73  ? 137.265 157.713 155.718 1.00 64.99  ? 147 ALA A CB  1 
ATOM   483  N N   . ILE A 1 74  ? 140.784 158.927 155.422 1.00 62.32  ? 148 ILE A N   1 
ATOM   484  C CA  . ILE A 1 74  ? 142.153 158.464 155.631 1.00 62.78  ? 148 ILE A CA  1 
ATOM   485  C C   . ILE A 1 74  ? 142.992 159.440 156.438 1.00 65.41  ? 148 ILE A C   1 
ATOM   486  O O   . ILE A 1 74  ? 144.012 159.034 157.026 1.00 67.12  ? 148 ILE A O   1 
ATOM   487  C CB  . ILE A 1 74  ? 142.839 158.155 154.280 1.00 65.71  ? 148 ILE A CB  1 
ATOM   488  C CG1 . ILE A 1 74  ? 144.049 157.242 154.485 1.00 64.04  ? 148 ILE A CG1 1 
ATOM   489  C CG2 . ILE A 1 74  ? 143.277 159.434 153.595 1.00 65.28  ? 148 ILE A CG2 1 
ATOM   490  C CD1 . ILE A 1 74  ? 143.690 155.855 154.967 1.00 63.94  ? 148 ILE A CD1 1 
ATOM   491  N N   . ALA A 1 75  ? 142.613 160.713 156.523 1.00 67.73  ? 149 ALA A N   1 
ATOM   492  C CA  . ALA A 1 75  ? 143.315 161.678 157.356 1.00 66.96  ? 149 ALA A CA  1 
ATOM   493  C C   . ALA A 1 75  ? 142.478 162.117 158.553 1.00 65.03  ? 149 ALA A C   1 
ATOM   494  O O   . ALA A 1 75  ? 143.039 162.681 159.506 1.00 65.58  ? 149 ALA A O   1 
ATOM   495  C CB  . ALA A 1 75  ? 143.723 162.887 156.528 1.00 63.88  ? 149 ALA A CB  1 
ATOM   496  N N   . SER A 1 76  ? 141.168 161.859 158.548 1.00 67.25  ? 150 SER A N   1 
ATOM   497  C CA  . SER A 1 76  ? 140.339 162.172 159.705 1.00 69.80  ? 150 SER A CA  1 
ATOM   498  C C   . SER A 1 76  ? 140.755 161.380 160.937 1.00 70.92  ? 150 SER A C   1 
ATOM   499  O O   . SER A 1 76  ? 140.440 161.789 162.060 1.00 74.14  ? 150 SER A O   1 
ATOM   500  C CB  . SER A 1 76  ? 138.868 161.907 159.383 1.00 71.26  ? 150 SER A CB  1 
ATOM   501  O OG  . SER A 1 76  ? 138.636 160.526 159.162 1.00 71.46  ? 150 SER A OG  1 
ATOM   502  N N   . ASP A 1 77  ? 141.452 160.262 160.754 1.00 66.43  ? 151 ASP A N   1 
ATOM   503  C CA  . ASP A 1 77  ? 141.995 159.480 161.856 1.00 69.62  ? 151 ASP A CA  1 
ATOM   504  C C   . ASP A 1 77  ? 143.465 159.839 162.026 1.00 68.95  ? 151 ASP A C   1 
ATOM   505  O O   . ASP A 1 77  ? 144.270 159.628 161.112 1.00 68.90  ? 151 ASP A O   1 
ATOM   506  C CB  . ASP A 1 77  ? 141.829 157.982 161.596 1.00 68.60  ? 151 ASP A CB  1 
ATOM   507  C CG  . ASP A 1 77  ? 142.583 157.129 162.598 1.00 71.60  ? 151 ASP A CG  1 
ATOM   508  O OD1 . ASP A 1 77  ? 142.667 157.526 163.780 1.00 70.61  ? 151 ASP A OD1 1 
ATOM   509  O OD2 . ASP A 1 77  ? 143.092 156.059 162.204 1.00 73.02  ? 151 ASP A OD2 1 
ATOM   510  N N   . GLU A 1 78  ? 143.812 160.381 163.193 1.00 70.33  ? 152 GLU A N   1 
ATOM   511  C CA  . GLU A 1 78  ? 145.185 160.783 163.467 1.00 70.44  ? 152 GLU A CA  1 
ATOM   512  C C   . GLU A 1 78  ? 146.074 159.619 163.879 1.00 71.05  ? 152 GLU A C   1 
ATOM   513  O O   . GLU A 1 78  ? 147.301 159.770 163.876 1.00 74.03  ? 152 GLU A O   1 
ATOM   514  C CB  . GLU A 1 78  ? 145.213 161.861 164.555 1.00 70.71  ? 152 GLU A CB  1 
ATOM   515  C CG  . GLU A 1 78  ? 144.764 161.380 165.928 1.00 72.67  ? 152 GLU A CG  1 
ATOM   516  C CD  . GLU A 1 78  ? 143.255 161.347 166.074 1.00 76.38  ? 152 GLU A CD  1 
ATOM   517  O OE1 . GLU A 1 78  ? 142.558 161.897 165.195 1.00 77.59  ? 152 GLU A OE1 1 
ATOM   518  O OE2 . GLU A 1 78  ? 142.765 160.770 167.068 1.00 73.93  ? 152 GLU A OE2 1 
ATOM   519  N N   . SER A 1 79  ? 145.492 158.472 164.237 1.00 59.84  ? 153 SER A N   1 
ATOM   520  C CA  . SER A 1 79  ? 146.304 157.305 164.563 1.00 62.88  ? 153 SER A CA  1 
ATOM   521  C C   . SER A 1 79  ? 147.079 156.822 163.345 1.00 63.01  ? 153 SER A C   1 
ATOM   522  O O   . SER A 1 79  ? 148.246 156.427 163.456 1.00 62.36  ? 153 SER A O   1 
ATOM   523  C CB  . SER A 1 79  ? 145.419 156.188 165.117 1.00 62.48  ? 153 SER A CB  1 
ATOM   524  O OG  . SER A 1 79  ? 146.182 155.030 165.408 1.00 63.89  ? 153 SER A OG  1 
ATOM   525  N N   . PHE A 1 80  ? 146.448 156.847 162.175 1.00 59.83  ? 154 PHE A N   1 
ATOM   526  C CA  . PHE A 1 80  ? 147.085 156.457 160.927 1.00 57.72  ? 154 PHE A CA  1 
ATOM   527  C C   . PHE A 1 80  ? 147.859 157.600 160.282 1.00 57.94  ? 154 PHE A C   1 
ATOM   528  O O   . PHE A 1 80  ? 148.521 157.383 159.261 1.00 64.18  ? 154 PHE A O   1 
ATOM   529  C CB  . PHE A 1 80  ? 146.029 155.928 159.949 1.00 58.34  ? 154 PHE A CB  1 
ATOM   530  C CG  . PHE A 1 80  ? 146.594 155.103 158.830 1.00 54.73  ? 154 PHE A CG  1 
ATOM   531  C CD1 . PHE A 1 80  ? 147.233 153.905 159.092 1.00 55.45  ? 154 PHE A CD1 1 
ATOM   532  C CD2 . PHE A 1 80  ? 146.483 155.524 157.516 1.00 54.48  ? 154 PHE A CD2 1 
ATOM   533  C CE1 . PHE A 1 80  ? 147.750 153.141 158.067 1.00 58.66  ? 154 PHE A CE1 1 
ATOM   534  C CE2 . PHE A 1 80  ? 147.001 154.765 156.485 1.00 56.72  ? 154 PHE A CE2 1 
ATOM   535  C CZ  . PHE A 1 80  ? 147.635 153.572 156.761 1.00 58.21  ? 154 PHE A CZ  1 
ATOM   536  N N   . GLY A 1 81  ? 147.791 158.805 160.850 1.00 51.95  ? 155 GLY A N   1 
ATOM   537  C CA  . GLY A 1 81  ? 148.493 159.934 160.260 1.00 53.29  ? 155 GLY A CA  1 
ATOM   538  C C   . GLY A 1 81  ? 150.000 159.773 160.290 1.00 53.70  ? 155 GLY A C   1 
ATOM   539  O O   . GLY A 1 81  ? 150.694 160.177 159.353 1.00 56.36  ? 155 GLY A O   1 
ATOM   540  N N   . ALA A 1 82  ? 150.529 159.184 161.364 1.00 47.70  ? 156 ALA A N   1 
ATOM   541  C CA  . ALA A 1 82  ? 151.964 158.937 161.446 1.00 49.86  ? 156 ALA A CA  1 
ATOM   542  C C   . ALA A 1 82  ? 152.426 157.900 160.433 1.00 50.51  ? 156 ALA A C   1 
ATOM   543  O O   . ALA A 1 82  ? 153.632 157.780 160.192 1.00 48.70  ? 156 ALA A O   1 
ATOM   544  C CB  . ALA A 1 82  ? 152.344 158.491 162.858 1.00 49.47  ? 156 ALA A CB  1 
ATOM   545  N N   . VAL A 1 83  ? 151.499 157.154 159.842 1.00 55.49  ? 157 VAL A N   1 
ATOM   546  C CA  . VAL A 1 83  ? 151.837 156.146 158.844 1.00 51.32  ? 157 VAL A CA  1 
ATOM   547  C C   . VAL A 1 83  ? 151.842 156.734 157.438 1.00 50.95  ? 157 VAL A C   1 
ATOM   548  O O   . VAL A 1 83  ? 152.698 156.389 156.620 1.00 52.80  ? 157 VAL A O   1 
ATOM   549  C CB  . VAL A 1 83  ? 150.858 154.961 158.963 1.00 51.21  ? 157 VAL A CB  1 
ATOM   550  C CG1 . VAL A 1 83  ? 151.081 153.967 157.844 1.00 52.85  ? 157 VAL A CG1 1 
ATOM   551  C CG2 . VAL A 1 83  ? 151.011 154.288 160.317 1.00 52.20  ? 157 VAL A CG2 1 
ATOM   552  N N   . LYS A 1 84  ? 150.901 157.634 157.139 1.00 51.84  ? 158 LYS A N   1 
ATOM   553  C CA  . LYS A 1 84  ? 150.801 158.196 155.797 1.00 51.53  ? 158 LYS A CA  1 
ATOM   554  C C   . LYS A 1 84  ? 152.016 159.033 155.420 1.00 53.14  ? 158 LYS A C   1 
ATOM   555  O O   . LYS A 1 84  ? 152.242 159.275 154.230 1.00 57.45  ? 158 LYS A O   1 
ATOM   556  C CB  . LYS A 1 84  ? 149.537 159.047 155.670 1.00 51.66  ? 158 LYS A CB  1 
ATOM   557  C CG  . LYS A 1 84  ? 148.249 158.303 155.974 1.00 54.32  ? 158 LYS A CG  1 
ATOM   558  C CD  . LYS A 1 84  ? 147.023 159.182 155.759 1.00 53.41  ? 158 LYS A CD  1 
ATOM   559  C CE  . LYS A 1 84  ? 147.269 160.249 154.701 1.00 54.80  ? 158 LYS A CE  1 
ATOM   560  N NZ  . LYS A 1 84  ? 146.206 161.289 154.696 1.00 57.17  ? 158 LYS A NZ  1 
ATOM   561  N N   . LYS A 1 85  ? 152.799 159.484 156.401 1.00 52.75  ? 159 LYS A N   1 
ATOM   562  C CA  . LYS A 1 85  ? 153.980 160.286 156.112 1.00 53.71  ? 159 LYS A CA  1 
ATOM   563  C C   . LYS A 1 85  ? 155.109 159.476 155.489 1.00 56.09  ? 159 LYS A C   1 
ATOM   564  O O   . LYS A 1 85  ? 156.094 160.070 155.037 1.00 56.79  ? 159 LYS A O   1 
ATOM   565  C CB  . LYS A 1 85  ? 154.478 160.963 157.390 1.00 53.06  ? 159 LYS A CB  1 
ATOM   566  C CG  . LYS A 1 85  ? 153.511 161.982 157.971 1.00 53.48  ? 159 LYS A CG  1 
ATOM   567  C CD  . LYS A 1 85  ? 154.068 162.614 159.236 1.00 57.10  ? 159 LYS A CD  1 
ATOM   568  C CE  . LYS A 1 85  ? 153.081 163.597 159.844 1.00 58.01  ? 159 LYS A CE  1 
ATOM   569  N NZ  . LYS A 1 85  ? 152.805 164.742 158.934 1.00 56.44  ? 159 LYS A NZ  1 
ATOM   570  N N   . LYS A 1 86  ? 154.996 158.148 155.452 1.00 46.65  ? 160 LYS A N   1 
ATOM   571  C CA  . LYS A 1 86  ? 156.048 157.283 154.936 1.00 45.40  ? 160 LYS A CA  1 
ATOM   572  C C   . LYS A 1 86  ? 155.619 156.543 153.670 1.00 49.70  ? 160 LYS A C   1 
ATOM   573  O O   . LYS A 1 86  ? 156.046 155.411 153.431 1.00 52.05  ? 160 LYS A O   1 
ATOM   574  C CB  . LYS A 1 86  ? 156.489 156.289 156.009 1.00 45.89  ? 160 LYS A CB  1 
ATOM   575  C CG  . LYS A 1 86  ? 156.826 156.930 157.344 1.00 47.18  ? 160 LYS A CG  1 
ATOM   576  C CD  . LYS A 1 86  ? 156.931 155.891 158.448 1.00 47.04  ? 160 LYS A CD  1 
ATOM   577  C CE  . LYS A 1 86  ? 157.929 154.803 158.092 1.00 46.33  ? 160 LYS A CE  1 
ATOM   578  N NZ  . LYS A 1 86  ? 157.988 153.743 159.136 1.00 44.67  ? 160 LYS A NZ  1 
ATOM   579  N N   . PHE A 1 87  ? 154.776 157.168 152.853 1.00 45.39  ? 161 PHE A N   1 
ATOM   580  C CA  . PHE A 1 87  ? 154.335 156.602 151.585 1.00 41.36  ? 161 PHE A CA  1 
ATOM   581  C C   . PHE A 1 87  ? 155.001 157.340 150.434 1.00 45.72  ? 161 PHE A C   1 
ATOM   582  O O   . PHE A 1 87  ? 155.021 158.575 150.410 1.00 53.21  ? 161 PHE A O   1 
ATOM   583  C CB  . PHE A 1 87  ? 152.813 156.680 151.441 1.00 42.52  ? 161 PHE A CB  1 
ATOM   584  C CG  . PHE A 1 87  ? 152.067 155.716 152.316 1.00 41.38  ? 161 PHE A CG  1 
ATOM   585  C CD1 . PHE A 1 87  ? 152.655 154.533 152.726 1.00 49.80  ? 161 PHE A CD1 1 
ATOM   586  C CD2 . PHE A 1 87  ? 150.769 155.986 152.712 1.00 41.34  ? 161 PHE A CD2 1 
ATOM   587  C CE1 . PHE A 1 87  ? 151.965 153.643 153.527 1.00 52.09  ? 161 PHE A CE1 1 
ATOM   588  C CE2 . PHE A 1 87  ? 150.075 155.100 153.511 1.00 42.33  ? 161 PHE A CE2 1 
ATOM   589  C CZ  . PHE A 1 87  ? 150.674 153.928 153.919 1.00 45.93  ? 161 PHE A CZ  1 
ATOM   590  N N   . THR A 1 88  ? 155.544 156.582 149.483 1.00 43.50  ? 162 THR A N   1 
ATOM   591  C CA  . THR A 1 88  ? 156.103 157.152 148.258 1.00 42.42  ? 162 THR A CA  1 
ATOM   592  C C   . THR A 1 88  ? 154.952 157.372 147.286 1.00 44.55  ? 162 THR A C   1 
ATOM   593  O O   . THR A 1 88  ? 154.644 156.526 146.444 1.00 49.63  ? 162 THR A O   1 
ATOM   594  C CB  . THR A 1 88  ? 157.176 156.232 147.646 1.00 46.47  ? 162 THR A CB  1 
ATOM   595  O OG1 . THR A 1 88  ? 158.252 156.065 148.575 1.00 50.39  ? 162 THR A OG1 1 
ATOM   596  C CG2 . THR A 1 88  ? 157.842 156.907 146.456 1.00 49.73  ? 162 THR A CG2 1 
ATOM   597  N N   . THR A 1 89  ? 154.307 158.528 147.410 1.00 61.77  ? 163 THR A N   1 
ATOM   598  C CA  . THR A 1 89  ? 153.090 158.806 146.660 1.00 64.87  ? 163 THR A CA  1 
ATOM   599  C C   . THR A 1 89  ? 153.386 158.980 145.175 1.00 65.91  ? 163 THR A C   1 
ATOM   600  O O   . THR A 1 89  ? 154.383 159.597 144.789 1.00 69.14  ? 163 THR A O   1 
ATOM   601  C CB  . THR A 1 89  ? 152.414 160.062 147.213 1.00 65.30  ? 163 THR A CB  1 
ATOM   602  O OG1 . THR A 1 89  ? 152.113 159.871 148.600 1.00 63.44  ? 163 THR A OG1 1 
ATOM   603  C CG2 . THR A 1 89  ? 151.126 160.359 146.466 1.00 64.33  ? 163 THR A CG2 1 
ATOM   604  N N   . PHE A 1 90  ? 152.508 158.426 144.339 1.00 74.59  ? 164 PHE A N   1 
ATOM   605  C CA  . PHE A 1 90  ? 152.583 158.578 142.894 1.00 76.70  ? 164 PHE A CA  1 
ATOM   606  C C   . PHE A 1 90  ? 151.197 158.898 142.353 1.00 76.95  ? 164 PHE A C   1 
ATOM   607  O O   . PHE A 1 90  ? 150.182 158.527 142.948 1.00 74.53  ? 164 PHE A O   1 
ATOM   608  C CB  . PHE A 1 90  ? 153.145 157.313 142.223 1.00 71.17  ? 164 PHE A CB  1 
ATOM   609  C CG  . PHE A 1 90  ? 152.177 156.163 142.178 1.00 72.47  ? 164 PHE A CG  1 
ATOM   610  C CD1 . PHE A 1 90  ? 152.072 155.290 143.247 1.00 74.47  ? 164 PHE A CD1 1 
ATOM   611  C CD2 . PHE A 1 90  ? 151.395 155.938 141.056 1.00 73.36  ? 164 PHE A CD2 1 
ATOM   612  C CE1 . PHE A 1 90  ? 151.189 154.228 143.207 1.00 75.04  ? 164 PHE A CE1 1 
ATOM   613  C CE2 . PHE A 1 90  ? 150.513 154.878 141.010 1.00 73.70  ? 164 PHE A CE2 1 
ATOM   614  C CZ  . PHE A 1 90  ? 150.409 154.021 142.087 1.00 73.91  ? 164 PHE A CZ  1 
ATOM   615  N N   . ARG A 1 91  ? 151.163 159.588 141.216 1.00 84.36  ? 165 ARG A N   1 
ATOM   616  C CA  . ARG A 1 91  ? 149.920 160.041 140.608 1.00 83.45  ? 165 ARG A CA  1 
ATOM   617  C C   . ARG A 1 91  ? 149.774 159.454 139.211 1.00 84.97  ? 165 ARG A C   1 
ATOM   618  O O   . ARG A 1 91  ? 150.760 159.310 138.481 1.00 84.39  ? 165 ARG A O   1 
ATOM   619  C CB  . ARG A 1 91  ? 149.869 161.569 140.551 1.00 83.73  ? 165 ARG A CB  1 
ATOM   620  C CG  . ARG A 1 91  ? 149.773 162.237 141.913 1.00 83.37  ? 165 ARG A CG  1 
ATOM   621  C CD  . ARG A 1 91  ? 149.674 163.753 141.856 1.00 83.25  ? 165 ARG A CD  1 
ATOM   622  N NE  . ARG A 1 91  ? 149.653 164.352 143.187 1.00 84.62  ? 165 ARG A NE  1 
ATOM   623  C CZ  . ARG A 1 91  ? 149.688 165.656 143.418 1.00 85.00  ? 165 ARG A CZ  1 
ATOM   624  N NH1 . ARG A 1 91  ? 149.741 166.511 142.404 1.00 83.42  ? 165 ARG A NH1 1 
ATOM   625  N NH2 . ARG A 1 91  ? 149.666 166.113 144.664 1.00 83.46  ? 165 ARG A NH2 1 
ATOM   626  N N   . GLU A 1 92  ? 148.539 159.116 138.848 1.00 89.37  ? 166 GLU A N   1 
ATOM   627  C CA  . GLU A 1 92  ? 148.263 158.568 137.528 1.00 89.12  ? 166 GLU A CA  1 
ATOM   628  C C   . GLU A 1 92  ? 148.449 159.630 136.450 1.00 90.13  ? 166 GLU A C   1 
ATOM   629  O O   . GLU A 1 92  ? 148.183 160.817 136.661 1.00 89.76  ? 166 GLU A O   1 
ATOM   630  C CB  . GLU A 1 92  ? 146.840 158.015 137.463 1.00 88.07  ? 166 GLU A CB  1 
ATOM   631  C CG  . GLU A 1 92  ? 146.600 156.785 138.321 1.00 87.56  ? 166 GLU A CG  1 
ATOM   632  C CD  . GLU A 1 92  ? 145.195 156.743 138.890 1.00 88.34  ? 166 GLU A CD  1 
ATOM   633  O OE1 . GLU A 1 92  ? 144.449 157.728 138.708 1.00 87.19  ? 166 GLU A OE1 1 
ATOM   634  O OE2 . GLU A 1 92  ? 144.837 155.727 139.522 1.00 87.39  ? 166 GLU A OE2 1 
ATOM   635  N N   . ASP A 1 93  ? 148.931 159.188 135.287 1.00 98.49  ? 167 ASP A N   1 
ATOM   636  C CA  . ASP A 1 93  ? 149.087 159.971 134.063 1.00 100.19 ? 167 ASP A CA  1 
ATOM   637  C C   . ASP A 1 93  ? 150.170 161.040 134.186 1.00 100.20 ? 167 ASP A C   1 
ATOM   638  O O   . ASP A 1 93  ? 150.484 161.704 133.190 1.00 99.38  ? 167 ASP A O   1 
ATOM   639  C CB  . ASP A 1 93  ? 147.762 160.622 133.628 1.00 99.41  ? 167 ASP A CB  1 
ATOM   640  C CG  . ASP A 1 93  ? 147.841 161.263 132.254 1.00 99.75  ? 167 ASP A CG  1 
ATOM   641  O OD1 . ASP A 1 93  ? 147.859 160.521 131.250 1.00 99.10  ? 167 ASP A OD1 1 
ATOM   642  O OD2 . ASP A 1 93  ? 147.883 162.509 132.179 1.00 98.76  ? 167 ASP A OD2 1 
ATOM   643  N N   . TYR A 1 94  ? 150.776 161.210 135.359 1.00 100.55 ? 168 TYR A N   1 
ATOM   644  C CA  . TYR A 1 94  ? 151.821 162.205 135.568 1.00 100.25 ? 168 TYR A CA  1 
ATOM   645  C C   . TYR A 1 94  ? 153.175 161.581 135.864 1.00 100.72 ? 168 TYR A C   1 
ATOM   646  O O   . TYR A 1 94  ? 154.164 161.903 135.198 1.00 101.20 ? 168 TYR A O   1 
ATOM   647  C CB  . TYR A 1 94  ? 151.429 163.149 136.705 1.00 100.78 ? 168 TYR A CB  1 
ATOM   648  C CG  . TYR A 1 94  ? 150.202 163.984 136.415 1.00 101.40 ? 168 TYR A CG  1 
ATOM   649  C CD1 . TYR A 1 94  ? 150.308 165.201 135.753 1.00 101.34 ? 168 TYR A CD1 1 
ATOM   650  C CD2 . TYR A 1 94  ? 148.941 163.554 136.802 1.00 100.34 ? 168 TYR A CD2 1 
ATOM   651  C CE1 . TYR A 1 94  ? 149.190 165.967 135.486 1.00 101.54 ? 168 TYR A CE1 1 
ATOM   652  C CE2 . TYR A 1 94  ? 147.815 164.314 136.538 1.00 100.48 ? 168 TYR A CE2 1 
ATOM   653  C CZ  . TYR A 1 94  ? 147.946 165.518 135.881 1.00 101.18 ? 168 TYR A CZ  1 
ATOM   654  O OH  . TYR A 1 94  ? 146.830 166.280 135.617 1.00 100.25 ? 168 TYR A OH  1 
ATOM   655  N N   . ASP A 1 95  ? 153.247 160.691 136.849 1.00 98.91  ? 169 ASP A N   1 
ATOM   656  C CA  . ASP A 1 95  ? 154.486 160.028 137.230 1.00 99.77  ? 169 ASP A CA  1 
ATOM   657  C C   . ASP A 1 95  ? 154.388 158.545 136.902 1.00 99.90  ? 169 ASP A C   1 
ATOM   658  O O   . ASP A 1 95  ? 153.434 157.876 137.313 1.00 99.91  ? 169 ASP A O   1 
ATOM   659  C CB  . ASP A 1 95  ? 154.776 160.222 138.720 1.00 98.33  ? 169 ASP A CB  1 
ATOM   660  C CG  . ASP A 1 95  ? 155.981 159.431 139.187 1.00 99.55  ? 169 ASP A CG  1 
ATOM   661  O OD1 . ASP A 1 95  ? 157.087 159.659 138.654 1.00 99.65  ? 169 ASP A OD1 1 
ATOM   662  O OD2 . ASP A 1 95  ? 155.822 158.580 140.088 1.00 98.92  ? 169 ASP A OD2 1 
ATOM   663  N N   . ASP A 1 96  ? 155.371 158.039 136.163 1.00 91.34  ? 170 ASP A N   1 
ATOM   664  C CA  . ASP A 1 96  ? 155.420 156.630 135.797 1.00 90.37  ? 170 ASP A CA  1 
ATOM   665  C C   . ASP A 1 96  ? 156.253 155.872 136.824 1.00 89.46  ? 170 ASP A C   1 
ATOM   666  O O   . ASP A 1 96  ? 157.457 156.120 136.963 1.00 89.63  ? 170 ASP A O   1 
ATOM   667  C CB  . ASP A 1 96  ? 155.990 156.455 134.389 1.00 91.30  ? 170 ASP A CB  1 
ATOM   668  C CG  . ASP A 1 96  ? 157.325 157.152 134.206 1.00 93.27  ? 170 ASP A CG  1 
ATOM   669  O OD1 . ASP A 1 96  ? 157.377 158.390 134.361 1.00 94.12  ? 170 ASP A OD1 1 
ATOM   670  O OD2 . ASP A 1 96  ? 158.321 156.460 133.908 1.00 90.37  ? 170 ASP A OD2 1 
ATOM   671  N N   . ILE A 1 97  ? 155.608 154.959 137.551 1.00 76.60  ? 171 ILE A N   1 
ATOM   672  C CA  . ILE A 1 97  ? 156.320 154.169 138.551 1.00 76.78  ? 171 ILE A CA  1 
ATOM   673  C C   . ILE A 1 97  ? 157.274 153.184 137.883 1.00 78.00  ? 171 ILE A C   1 
ATOM   674  O O   . ILE A 1 97  ? 158.428 153.041 138.304 1.00 78.48  ? 171 ILE A O   1 
ATOM   675  C CB  . ILE A 1 97  ? 155.313 153.475 139.488 1.00 76.61  ? 171 ILE A CB  1 
ATOM   676  C CG1 . ILE A 1 97  ? 154.318 152.626 138.695 1.00 74.50  ? 171 ILE A CG1 1 
ATOM   677  C CG2 . ILE A 1 97  ? 154.587 154.502 140.338 1.00 77.52  ? 171 ILE A CG2 1 
ATOM   678  C CD1 . ILE A 1 97  ? 153.392 151.806 139.557 1.00 72.71  ? 171 ILE A CD1 1 
ATOM   679  N N   . SER A 1 98  ? 156.817 152.509 136.825 1.00 78.39  ? 172 SER A N   1 
ATOM   680  C CA  . SER A 1 98  ? 157.645 151.637 135.996 1.00 76.39  ? 172 SER A CA  1 
ATOM   681  C C   . SER A 1 98  ? 158.512 150.681 136.807 1.00 74.98  ? 172 SER A C   1 
ATOM   682  O O   . SER A 1 98  ? 158.001 149.878 137.594 1.00 75.93  ? 172 SER A O   1 
ATOM   683  C CB  . SER A 1 98  ? 158.528 152.478 135.072 1.00 77.44  ? 172 SER A CB  1 
ATOM   684  O OG  . SER A 1 98  ? 157.747 153.180 134.120 1.00 76.68  ? 172 SER A OG  1 
ATOM   685  N N   . ASN A 1 99  ? 159.829 150.767 136.617 1.00 73.48  ? 173 ASN A N   1 
ATOM   686  C CA  . ASN A 1 99  ? 160.779 149.849 137.249 1.00 74.92  ? 173 ASN A CA  1 
ATOM   687  C C   . ASN A 1 99  ? 161.249 150.414 138.592 1.00 76.02  ? 173 ASN A C   1 
ATOM   688  O O   . ASN A 1 99  ? 162.409 150.778 138.793 1.00 78.17  ? 173 ASN A O   1 
ATOM   689  C CB  . ASN A 1 99  ? 161.945 149.568 136.309 1.00 74.23  ? 173 ASN A CB  1 
ATOM   690  C CG  . ASN A 1 99  ? 162.634 150.836 135.829 1.00 76.13  ? 173 ASN A CG  1 
ATOM   691  O OD1 . ASN A 1 99  ? 162.299 151.942 136.253 1.00 77.24  ? 173 ASN A OD1 1 
ATOM   692  N ND2 . ASN A 1 99  ? 163.605 150.677 134.937 1.00 75.67  ? 173 ASN A ND2 1 
ATOM   693  N N   . GLN A 1 100 ? 160.306 150.468 139.533 1.00 70.42  ? 174 GLN A N   1 
ATOM   694  C CA  . GLN A 1 100 ? 160.613 150.906 140.887 1.00 66.16  ? 174 GLN A CA  1 
ATOM   695  C C   . GLN A 1 100 ? 159.972 150.044 141.964 1.00 63.56  ? 174 GLN A C   1 
ATOM   696  O O   . GLN A 1 100 ? 160.107 150.372 143.146 1.00 63.32  ? 174 GLN A O   1 
ATOM   697  C CB  . GLN A 1 100 ? 160.178 152.367 141.093 1.00 64.35  ? 174 GLN A CB  1 
ATOM   698  C CG  . GLN A 1 100 ? 161.152 153.396 140.545 1.00 66.35  ? 174 GLN A CG  1 
ATOM   699  C CD  . GLN A 1 100 ? 160.570 154.796 140.530 1.00 68.37  ? 174 GLN A CD  1 
ATOM   700  O OE1 . GLN A 1 100 ? 159.418 154.998 140.146 1.00 67.42  ? 174 GLN A OE1 1 
ATOM   701  N NE2 . GLN A 1 100 ? 161.365 155.773 140.952 1.00 67.77  ? 174 GLN A NE2 1 
ATOM   702  N N   . ILE A 1 101 ? 159.284 148.963 141.604 1.00 51.93  ? 175 ILE A N   1 
ATOM   703  C CA  . ILE A 1 101 ? 158.485 148.183 142.541 1.00 46.13  ? 175 ILE A CA  1 
ATOM   704  C C   . ILE A 1 101 ? 158.899 146.722 142.443 1.00 45.57  ? 175 ILE A C   1 
ATOM   705  O O   . ILE A 1 101 ? 158.998 146.174 141.341 1.00 54.00  ? 175 ILE A O   1 
ATOM   706  C CB  . ILE A 1 101 ? 156.980 148.343 142.260 1.00 43.78  ? 175 ILE A CB  1 
ATOM   707  C CG1 . ILE A 1 101 ? 156.622 149.829 142.198 1.00 48.23  ? 175 ILE A CG1 1 
ATOM   708  C CG2 . ILE A 1 101 ? 156.161 147.628 143.322 1.00 48.14  ? 175 ILE A CG2 1 
ATOM   709  C CD1 . ILE A 1 101 ? 155.151 150.111 142.193 1.00 51.39  ? 175 ILE A CD1 1 
ATOM   710  N N   . ASP A 1 102 ? 159.130 146.092 143.597 1.00 34.81  ? 176 ASP A N   1 
ATOM   711  C CA  . ASP A 1 102 ? 159.577 144.703 143.609 1.00 33.16  ? 176 ASP A CA  1 
ATOM   712  C C   . ASP A 1 102 ? 158.412 143.729 143.472 1.00 42.66  ? 176 ASP A C   1 
ATOM   713  O O   . ASP A 1 102 ? 158.511 142.747 142.729 1.00 50.28  ? 176 ASP A O   1 
ATOM   714  C CB  . ASP A 1 102 ? 160.362 144.417 144.888 1.00 41.92  ? 176 ASP A CB  1 
ATOM   715  C CG  . ASP A 1 102 ? 161.559 145.329 145.050 1.00 50.96  ? 176 ASP A CG  1 
ATOM   716  O OD1 . ASP A 1 102 ? 162.417 145.349 144.144 1.00 54.98  ? 176 ASP A OD1 1 
ATOM   717  O OD2 . ASP A 1 102 ? 161.636 146.035 146.077 1.00 52.76  ? 176 ASP A OD2 1 
ATOM   718  N N   . PHE A 1 103 ? 157.315 143.970 144.187 1.00 34.27  ? 177 PHE A N   1 
ATOM   719  C CA  . PHE A 1 103 ? 156.119 143.150 144.042 1.00 32.83  ? 177 PHE A CA  1 
ATOM   720  C C   . PHE A 1 103 ? 154.918 143.936 144.545 1.00 30.24  ? 177 PHE A C   1 
ATOM   721  O O   . PHE A 1 103 ? 155.054 144.891 145.314 1.00 40.56  ? 177 PHE A O   1 
ATOM   722  C CB  . PHE A 1 103 ? 156.257 141.808 144.774 1.00 32.72  ? 177 PHE A CB  1 
ATOM   723  C CG  . PHE A 1 103 ? 156.002 141.882 146.251 1.00 25.07  ? 177 PHE A CG  1 
ATOM   724  C CD1 . PHE A 1 103 ? 156.938 142.443 147.101 1.00 32.95  ? 177 PHE A CD1 1 
ATOM   725  C CD2 . PHE A 1 103 ? 154.840 141.361 146.793 1.00 28.60  ? 177 PHE A CD2 1 
ATOM   726  C CE1 . PHE A 1 103 ? 156.710 142.502 148.460 1.00 30.22  ? 177 PHE A CE1 1 
ATOM   727  C CE2 . PHE A 1 103 ? 154.608 141.417 148.151 1.00 32.42  ? 177 PHE A CE2 1 
ATOM   728  C CZ  . PHE A 1 103 ? 155.544 141.989 148.985 1.00 31.12  ? 177 PHE A CZ  1 
ATOM   729  N N   . ILE A 1 104 ? 153.737 143.517 144.097 1.00 27.95  ? 178 ILE A N   1 
ATOM   730  C CA  . ILE A 1 104 ? 152.495 144.241 144.338 1.00 21.30  ? 178 ILE A CA  1 
ATOM   731  C C   . ILE A 1 104 ? 151.596 143.421 145.252 1.00 29.15  ? 178 ILE A C   1 
ATOM   732  O O   . ILE A 1 104 ? 151.590 142.186 145.212 1.00 37.21  ? 178 ILE A O   1 
ATOM   733  C CB  . ILE A 1 104 ? 151.768 144.564 143.015 1.00 20.22  ? 178 ILE A CB  1 
ATOM   734  C CG1 . ILE A 1 104 ? 152.759 145.064 141.968 1.00 30.28  ? 178 ILE A CG1 1 
ATOM   735  C CG2 . ILE A 1 104 ? 150.679 145.601 143.233 1.00 30.10  ? 178 ILE A CG2 1 
ATOM   736  C CD1 . ILE A 1 104 ? 152.159 145.191 140.592 1.00 29.47  ? 178 ILE A CD1 1 
ATOM   737  N N   . ILE A 1 105 ? 150.832 144.124 146.085 1.00 20.66  ? 179 ILE A N   1 
ATOM   738  C CA  . ILE A 1 105 ? 149.772 143.535 146.892 1.00 14.57  ? 179 ILE A CA  1 
ATOM   739  C C   . ILE A 1 105 ? 148.468 144.226 146.521 1.00 27.56  ? 179 ILE A C   1 
ATOM   740  O O   . ILE A 1 105 ? 148.376 145.457 146.578 1.00 38.35  ? 179 ILE A O   1 
ATOM   741  C CB  . ILE A 1 105 ? 150.055 143.672 148.399 1.00 14.14  ? 179 ILE A CB  1 
ATOM   742  C CG1 . ILE A 1 105 ? 151.415 143.068 148.746 1.00 21.22  ? 179 ILE A CG1 1 
ATOM   743  C CG2 . ILE A 1 105 ? 148.956 143.005 149.206 1.00 25.86  ? 179 ILE A CG2 1 
ATOM   744  C CD1 . ILE A 1 105 ? 151.769 143.167 150.210 1.00 25.49  ? 179 ILE A CD1 1 
ATOM   745  N N   . CYS A 1 106 ? 147.467 143.439 146.142 1.00 33.04  ? 180 CYS A N   1 
ATOM   746  C CA  . CYS A 1 106 ? 146.183 143.960 145.697 1.00 30.09  ? 180 CYS A CA  1 
ATOM   747  C C   . CYS A 1 106 ? 145.093 143.624 146.704 1.00 37.68  ? 180 CYS A C   1 
ATOM   748  O O   . CYS A 1 106 ? 145.074 142.527 147.272 1.00 38.26  ? 180 CYS A O   1 
ATOM   749  C CB  . CYS A 1 106 ? 145.810 143.405 144.321 1.00 31.68  ? 180 CYS A CB  1 
ATOM   750  S SG  . CYS A 1 106 ? 146.863 143.988 142.977 1.00 54.10  ? 180 CYS A SG  1 
ATOM   751  N N   . LEU A 1 107 ? 144.189 144.576 146.920 1.00 32.57  ? 181 LEU A N   1 
ATOM   752  C CA  . LEU A 1 107 ? 143.087 144.430 147.860 1.00 19.01  ? 181 LEU A CA  1 
ATOM   753  C C   . LEU A 1 107 ? 141.783 144.767 147.156 1.00 27.73  ? 181 LEU A C   1 
ATOM   754  O O   . LEU A 1 107 ? 141.683 145.810 146.502 1.00 40.54  ? 181 LEU A O   1 
ATOM   755  C CB  . LEU A 1 107 ? 143.274 145.350 149.071 1.00 24.44  ? 181 LEU A CB  1 
ATOM   756  C CG  . LEU A 1 107 ? 144.481 145.127 149.982 1.00 24.60  ? 181 LEU A CG  1 
ATOM   757  C CD1 . LEU A 1 107 ? 144.581 146.244 151.004 1.00 30.36  ? 181 LEU A CD1 1 
ATOM   758  C CD2 . LEU A 1 107 ? 144.392 143.784 150.677 1.00 38.55  ? 181 LEU A CD2 1 
ATOM   759  N N   . GLY A 1 108 ? 140.789 143.892 147.286 1.00 33.58  ? 182 GLY A N   1 
ATOM   760  C CA  . GLY A 1 108 ? 139.445 144.244 146.870 1.00 41.68  ? 182 GLY A CA  1 
ATOM   761  C C   . GLY A 1 108 ? 138.717 143.273 145.963 1.00 42.17  ? 182 GLY A C   1 
ATOM   762  O O   . GLY A 1 108 ? 137.515 143.055 146.142 1.00 50.68  ? 182 GLY A O   1 
ATOM   763  N N   . GLY A 1 109 ? 139.404 142.684 145.000 1.00 29.45  ? 183 GLY A N   1 
ATOM   764  C CA  . GLY A 1 109 ? 138.761 141.769 144.082 1.00 34.89  ? 183 GLY A CA  1 
ATOM   765  C C   . GLY A 1 109 ? 139.523 141.670 142.777 1.00 37.83  ? 183 GLY A C   1 
ATOM   766  O O   . GLY A 1 109 ? 140.662 142.112 142.662 1.00 45.96  ? 183 GLY A O   1 
ATOM   767  N N   . ASP A 1 110 ? 138.853 141.068 141.791 1.00 31.40  ? 184 ASP A N   1 
ATOM   768  C CA  . ASP A 1 110 ? 139.491 140.776 140.511 1.00 25.89  ? 184 ASP A CA  1 
ATOM   769  C C   . ASP A 1 110 ? 139.854 142.050 139.758 1.00 31.54  ? 184 ASP A C   1 
ATOM   770  O O   . ASP A 1 110 ? 140.952 142.153 139.197 1.00 43.19  ? 184 ASP A O   1 
ATOM   771  C CB  . ASP A 1 110 ? 138.569 139.902 139.663 1.00 34.34  ? 184 ASP A CB  1 
ATOM   772  C CG  . ASP A 1 110 ? 138.579 138.454 140.097 1.00 40.54  ? 184 ASP A CG  1 
ATOM   773  O OD1 . ASP A 1 110 ? 139.660 137.947 140.455 1.00 41.19  ? 184 ASP A OD1 1 
ATOM   774  O OD2 . ASP A 1 110 ? 137.503 137.820 140.083 1.00 43.68  ? 184 ASP A OD2 1 
ATOM   775  N N   . GLY A 1 111 ? 138.950 143.032 139.746 1.00 35.13  ? 185 GLY A N   1 
ATOM   776  C CA  . GLY A 1 111 ? 139.182 144.232 138.957 1.00 31.17  ? 185 GLY A CA  1 
ATOM   777  C C   . GLY A 1 111 ? 140.444 144.965 139.362 1.00 29.23  ? 185 GLY A C   1 
ATOM   778  O O   . GLY A 1 111 ? 141.143 145.530 138.517 1.00 37.07  ? 185 GLY A O   1 
ATOM   779  N N   . THR A 1 112 ? 140.758 144.954 140.659 1.00 26.78  ? 186 THR A N   1 
ATOM   780  C CA  . THR A 1 112 ? 142.002 145.547 141.135 1.00 28.03  ? 186 THR A CA  1 
ATOM   781  C C   . THR A 1 112 ? 143.198 144.967 140.391 1.00 33.66  ? 186 THR A C   1 
ATOM   782  O O   . THR A 1 112 ? 144.059 145.707 139.900 1.00 43.53  ? 186 THR A O   1 
ATOM   783  C CB  . THR A 1 112 ? 142.143 145.325 142.641 1.00 33.60  ? 186 THR A CB  1 
ATOM   784  O OG1 . THR A 1 112 ? 141.074 145.989 143.326 1.00 37.24  ? 186 THR A OG1 1 
ATOM   785  C CG2 . THR A 1 112 ? 143.466 145.869 143.138 1.00 35.60  ? 186 THR A CG2 1 
ATOM   786  N N   . LEU A 1 113 ? 143.242 143.637 140.263 1.00 35.26  ? 187 LEU A N   1 
ATOM   787  C CA  . LEU A 1 113 ? 144.310 143.007 139.493 1.00 31.92  ? 187 LEU A CA  1 
ATOM   788  C C   . LEU A 1 113 ? 144.349 143.544 138.071 1.00 31.24  ? 187 LEU A C   1 
ATOM   789  O O   . LEU A 1 113 ? 145.428 143.830 137.537 1.00 37.48  ? 187 LEU A O   1 
ATOM   790  C CB  . LEU A 1 113 ? 144.136 141.490 139.488 1.00 28.23  ? 187 LEU A CB  1 
ATOM   791  C CG  . LEU A 1 113 ? 145.325 140.712 138.922 1.00 35.01  ? 187 LEU A CG  1 
ATOM   792  C CD1 . LEU A 1 113 ? 146.610 141.142 139.588 1.00 37.55  ? 187 LEU A CD1 1 
ATOM   793  C CD2 . LEU A 1 113 ? 145.120 139.218 139.080 1.00 36.99  ? 187 LEU A CD2 1 
ATOM   794  N N   . LEU A 1 114 ? 143.178 143.712 137.452 1.00 33.86  ? 188 LEU A N   1 
ATOM   795  C CA  . LEU A 1 114 ? 143.130 144.304 136.122 1.00 36.04  ? 188 LEU A CA  1 
ATOM   796  C C   . LEU A 1 114 ? 143.759 145.689 136.129 1.00 33.57  ? 188 LEU A C   1 
ATOM   797  O O   . LEU A 1 114 ? 144.574 146.015 135.257 1.00 39.24  ? 188 LEU A O   1 
ATOM   798  C CB  . LEU A 1 114 ? 141.684 144.369 135.631 1.00 36.73  ? 188 LEU A CB  1 
ATOM   799  C CG  . LEU A 1 114 ? 141.189 143.207 134.769 1.00 34.08  ? 188 LEU A CG  1 
ATOM   800  C CD1 . LEU A 1 114 ? 141.512 141.872 135.418 1.00 37.09  ? 188 LEU A CD1 1 
ATOM   801  C CD2 . LEU A 1 114 ? 139.696 143.332 134.524 1.00 36.07  ? 188 LEU A CD2 1 
ATOM   802  N N   . TYR A 1 115 ? 143.426 146.500 137.136 1.00 34.45  ? 189 TYR A N   1 
ATOM   803  C CA  . TYR A 1 115 ? 144.051 147.811 137.262 1.00 32.52  ? 189 TYR A CA  1 
ATOM   804  C C   . TYR A 1 115 ? 145.556 147.673 137.443 1.00 34.86  ? 189 TYR A C   1 
ATOM   805  O O   . TYR A 1 115 ? 146.330 148.479 136.913 1.00 40.58  ? 189 TYR A O   1 
ATOM   806  C CB  . TYR A 1 115 ? 143.426 148.576 138.428 1.00 36.40  ? 189 TYR A CB  1 
ATOM   807  C CG  . TYR A 1 115 ? 144.038 149.934 138.681 1.00 35.74  ? 189 TYR A CG  1 
ATOM   808  C CD1 . TYR A 1 115 ? 143.774 151.003 137.835 1.00 38.81  ? 189 TYR A CD1 1 
ATOM   809  C CD2 . TYR A 1 115 ? 144.869 150.150 139.770 1.00 39.00  ? 189 TYR A CD2 1 
ATOM   810  C CE1 . TYR A 1 115 ? 144.327 152.246 138.064 1.00 40.37  ? 189 TYR A CE1 1 
ATOM   811  C CE2 . TYR A 1 115 ? 145.425 151.389 140.007 1.00 41.63  ? 189 TYR A CE2 1 
ATOM   812  C CZ  . TYR A 1 115 ? 145.152 152.433 139.151 1.00 41.89  ? 189 TYR A CZ  1 
ATOM   813  O OH  . TYR A 1 115 ? 145.707 153.669 139.385 1.00 46.07  ? 189 TYR A OH  1 
ATOM   814  N N   . ALA A 1 116 ? 145.989 146.638 138.169 1.00 36.70  ? 190 ALA A N   1 
ATOM   815  C CA  . ALA A 1 116 ? 147.417 146.391 138.324 1.00 33.12  ? 190 ALA A CA  1 
ATOM   816  C C   . ALA A 1 116 ? 148.084 146.127 136.982 1.00 34.71  ? 190 ALA A C   1 
ATOM   817  O O   . ALA A 1 116 ? 149.255 146.475 136.792 1.00 41.69  ? 190 ALA A O   1 
ATOM   818  C CB  . ALA A 1 116 ? 147.649 145.218 139.276 1.00 37.19  ? 190 ALA A CB  1 
ATOM   819  N N   . SER A 1 117 ? 147.362 145.515 136.041 1.00 34.86  ? 191 SER A N   1 
ATOM   820  C CA  . SER A 1 117 ? 147.925 145.311 134.712 1.00 31.50  ? 191 SER A CA  1 
ATOM   821  C C   . SER A 1 117 ? 147.949 146.606 133.913 1.00 36.85  ? 191 SER A C   1 
ATOM   822  O O   . SER A 1 117 ? 148.769 146.755 133.000 1.00 40.79  ? 191 SER A O   1 
ATOM   823  C CB  . SER A 1 117 ? 147.136 144.238 133.963 1.00 39.31  ? 191 SER A CB  1 
ATOM   824  O OG  . SER A 1 117 ? 147.636 144.062 132.649 1.00 44.69  ? 191 SER A OG  1 
ATOM   825  N N   . SER A 1 118 ? 147.062 147.550 134.238 1.00 35.13  ? 192 SER A N   1 
ATOM   826  C CA  . SER A 1 118 ? 147.004 148.799 133.486 1.00 28.67  ? 192 SER A CA  1 
ATOM   827  C C   . SER A 1 118 ? 148.201 149.691 133.791 1.00 33.53  ? 192 SER A C   1 
ATOM   828  O O   . SER A 1 118 ? 148.694 150.400 132.907 1.00 38.78  ? 192 SER A O   1 
ATOM   829  C CB  . SER A 1 118 ? 145.698 149.532 133.790 1.00 39.36  ? 192 SER A CB  1 
ATOM   830  O OG  . SER A 1 118 ? 144.580 148.781 133.350 1.00 44.91  ? 192 SER A OG  1 
ATOM   831  N N   . LEU A 1 119 ? 148.681 149.671 135.036 1.00 38.83  ? 193 LEU A N   1 
ATOM   832  C CA  . LEU A 1 119 ? 149.780 150.548 135.422 1.00 38.79  ? 193 LEU A CA  1 
ATOM   833  C C   . LEU A 1 119 ? 151.121 150.085 134.871 1.00 40.21  ? 193 LEU A C   1 
ATOM   834  O O   . LEU A 1 119 ? 152.060 150.885 134.811 1.00 45.03  ? 193 LEU A O   1 
ATOM   835  C CB  . LEU A 1 119 ? 149.859 150.651 136.945 1.00 38.13  ? 193 LEU A CB  1 
ATOM   836  C CG  . LEU A 1 119 ? 148.680 151.315 137.656 1.00 37.11  ? 193 LEU A CG  1 
ATOM   837  C CD1 . LEU A 1 119 ? 148.850 151.211 139.162 1.00 40.83  ? 193 LEU A CD1 1 
ATOM   838  C CD2 . LEU A 1 119 ? 148.539 152.766 137.227 1.00 42.50  ? 193 LEU A CD2 1 
ATOM   839  N N   . PHE A 1 120 ? 151.234 148.822 134.470 1.00 38.07  ? 194 PHE A N   1 
ATOM   840  C CA  . PHE A 1 120 ? 152.490 148.245 133.996 1.00 36.96  ? 194 PHE A CA  1 
ATOM   841  C C   . PHE A 1 120 ? 152.287 147.744 132.571 1.00 39.49  ? 194 PHE A C   1 
ATOM   842  O O   . PHE A 1 120 ? 151.835 146.614 132.361 1.00 43.44  ? 194 PHE A O   1 
ATOM   843  C CB  . PHE A 1 120 ? 152.952 147.122 134.919 1.00 36.36  ? 194 PHE A CB  1 
ATOM   844  C CG  . PHE A 1 120 ? 153.344 147.589 136.289 1.00 36.47  ? 194 PHE A CG  1 
ATOM   845  C CD1 . PHE A 1 120 ? 154.600 148.123 136.521 1.00 40.91  ? 194 PHE A CD1 1 
ATOM   846  C CD2 . PHE A 1 120 ? 152.453 147.505 137.344 1.00 40.89  ? 194 PHE A CD2 1 
ATOM   847  C CE1 . PHE A 1 120 ? 154.962 148.555 137.780 1.00 43.93  ? 194 PHE A CE1 1 
ATOM   848  C CE2 . PHE A 1 120 ? 152.809 147.940 138.603 1.00 40.77  ? 194 PHE A CE2 1 
ATOM   849  C CZ  . PHE A 1 120 ? 154.065 148.462 138.822 1.00 42.90  ? 194 PHE A CZ  1 
ATOM   850  N N   . GLN A 1 121 ? 152.620 148.585 131.593 1.00 39.30  ? 195 GLN A N   1 
ATOM   851  C CA  . GLN A 1 121 ? 152.517 148.195 130.193 1.00 40.68  ? 195 GLN A CA  1 
ATOM   852  C C   . GLN A 1 121 ? 153.724 147.401 129.713 1.00 40.43  ? 195 GLN A C   1 
ATOM   853  O O   . GLN A 1 121 ? 153.701 146.890 128.589 1.00 43.04  ? 195 GLN A O   1 
ATOM   854  C CB  . GLN A 1 121 ? 152.328 149.436 129.313 1.00 38.01  ? 195 GLN A CB  1 
ATOM   855  C CG  . GLN A 1 121 ? 151.076 150.296 129.594 1.00 42.00  ? 195 GLN A CG  1 
ATOM   856  C CD  . GLN A 1 121 ? 149.738 149.544 129.620 1.00 42.71  ? 195 GLN A CD  1 
ATOM   857  O OE1 . GLN A 1 121 ? 149.675 148.316 129.583 1.00 42.54  ? 195 GLN A OE1 1 
ATOM   858  N NE2 . GLN A 1 121 ? 148.653 150.307 129.686 1.00 41.97  ? 195 GLN A NE2 1 
ATOM   859  N N   . GLY A 1 122 ? 154.766 147.288 130.532 1.00 36.62  ? 196 GLY A N   1 
ATOM   860  C CA  . GLY A 1 122 ? 155.914 146.469 130.204 1.00 33.41  ? 196 GLY A CA  1 
ATOM   861  C C   . GLY A 1 122 ? 156.079 145.326 131.183 1.00 37.83  ? 196 GLY A C   1 
ATOM   862  O O   . GLY A 1 122 ? 155.113 144.619 131.482 1.00 43.31  ? 196 GLY A O   1 
ATOM   863  N N   . SER A 1 123 ? 157.294 145.131 131.688 1.00 38.21  ? 197 SER A N   1 
ATOM   864  C CA  . SER A 1 123 ? 157.521 144.104 132.694 1.00 35.80  ? 197 SER A CA  1 
ATOM   865  C C   . SER A 1 123 ? 156.801 144.467 133.986 1.00 40.52  ? 197 SER A C   1 
ATOM   866  O O   . SER A 1 123 ? 156.829 145.618 134.430 1.00 47.01  ? 197 SER A O   1 
ATOM   867  C CB  . SER A 1 123 ? 159.016 143.928 132.951 1.00 44.17  ? 197 SER A CB  1 
ATOM   868  O OG  . SER A 1 123 ? 159.262 142.809 133.784 1.00 46.40  ? 197 SER A OG  1 
ATOM   869  N N   . VAL A 1 124 ? 156.152 143.477 134.590 1.00 39.11  ? 198 VAL A N   1 
ATOM   870  C CA  . VAL A 1 124 ? 155.324 143.706 135.771 1.00 40.56  ? 198 VAL A CA  1 
ATOM   871  C C   . VAL A 1 124 ? 155.805 142.822 136.918 1.00 41.59  ? 198 VAL A C   1 
ATOM   872  O O   . VAL A 1 124 ? 156.116 141.640 136.709 1.00 39.27  ? 198 VAL A O   1 
ATOM   873  C CB  . VAL A 1 124 ? 153.837 143.480 135.446 1.00 36.18  ? 198 VAL A CB  1 
ATOM   874  C CG1 . VAL A 1 124 ? 153.578 142.040 135.058 1.00 30.99  ? 198 VAL A CG1 1 
ATOM   875  C CG2 . VAL A 1 124 ? 152.957 143.881 136.621 1.00 39.23  ? 198 VAL A CG2 1 
ATOM   876  N N   . PRO A 1 125 ? 155.918 143.357 138.130 1.00 37.09  ? 199 PRO A N   1 
ATOM   877  C CA  . PRO A 1 125 ? 156.366 142.549 139.268 1.00 29.68  ? 199 PRO A CA  1 
ATOM   878  C C   . PRO A 1 125 ? 155.286 141.579 139.713 1.00 36.87  ? 199 PRO A C   1 
ATOM   879  O O   . PRO A 1 125 ? 154.112 141.734 139.343 1.00 47.55  ? 199 PRO A O   1 
ATOM   880  C CB  . PRO A 1 125 ? 156.653 143.603 140.348 1.00 33.67  ? 199 PRO A CB  1 
ATOM   881  C CG  . PRO A 1 125 ? 155.779 144.746 139.985 1.00 34.65  ? 199 PRO A CG  1 
ATOM   882  C CD  . PRO A 1 125 ? 155.795 144.780 138.489 1.00 33.59  ? 199 PRO A CD  1 
ATOM   883  N N   . PRO A 1 126 ? 155.644 140.560 140.496 1.00 15.92  ? 200 PRO A N   1 
ATOM   884  C CA  . PRO A 1 126 ? 154.635 139.603 140.968 1.00 24.98  ? 200 PRO A CA  1 
ATOM   885  C C   . PRO A 1 126 ? 153.580 140.278 141.831 1.00 23.37  ? 200 PRO A C   1 
ATOM   886  O O   . PRO A 1 126 ? 153.843 141.268 142.517 1.00 35.84  ? 200 PRO A O   1 
ATOM   887  C CB  . PRO A 1 126 ? 155.447 138.583 141.777 1.00 27.92  ? 200 PRO A CB  1 
ATOM   888  C CG  . PRO A 1 126 ? 156.814 139.143 141.916 1.00 28.52  ? 200 PRO A CG  1 
ATOM   889  C CD  . PRO A 1 126 ? 157.014 140.159 140.851 1.00 21.09  ? 200 PRO A CD  1 
ATOM   890  N N   . VAL A 1 127 ? 152.370 139.728 141.784 1.00 16.28  ? 201 VAL A N   1 
ATOM   891  C CA  . VAL A 1 127 ? 151.214 140.292 142.467 1.00 19.71  ? 201 VAL A CA  1 
ATOM   892  C C   . VAL A 1 127 ? 150.701 139.280 143.481 1.00 27.10  ? 201 VAL A C   1 
ATOM   893  O O   . VAL A 1 127 ? 150.546 138.096 143.161 1.00 33.09  ? 201 VAL A O   1 
ATOM   894  C CB  . VAL A 1 127 ? 150.100 140.675 141.477 1.00 19.99  ? 201 VAL A CB  1 
ATOM   895  C CG1 . VAL A 1 127 ? 148.902 141.213 142.230 1.00 30.22  ? 201 VAL A CG1 1 
ATOM   896  C CG2 . VAL A 1 127 ? 150.610 141.693 140.470 1.00 28.17  ? 201 VAL A CG2 1 
ATOM   897  N N   . MET A 1 128 ? 150.439 139.748 144.698 1.00 25.49  ? 202 MET A N   1 
ATOM   898  C CA  . MET A 1 128 ? 149.879 138.932 145.772 1.00 15.00  ? 202 MET A CA  1 
ATOM   899  C C   . MET A 1 128 ? 148.469 139.455 146.041 1.00 26.36  ? 202 MET A C   1 
ATOM   900  O O   . MET A 1 128 ? 148.260 140.305 146.908 1.00 37.87  ? 202 MET A O   1 
ATOM   901  C CB  . MET A 1 128 ? 150.761 138.995 147.015 1.00 18.18  ? 202 MET A CB  1 
ATOM   902  C CG  . MET A 1 128 ? 150.405 137.995 148.095 1.00 19.91  ? 202 MET A CG  1 
ATOM   903  S SD  . MET A 1 128 ? 151.620 138.006 149.425 1.00 28.34  ? 202 MET A SD  1 
ATOM   904  C CE  . MET A 1 128 ? 150.569 137.986 150.868 1.00 30.14  ? 202 MET A CE  1 
ATOM   905  N N   . ALA A 1 129 ? 147.502 138.939 145.287 1.00 19.40  ? 203 ALA A N   1 
ATOM   906  C CA  . ALA A 1 129 ? 146.136 139.436 145.349 1.00 15.41  ? 203 ALA A CA  1 
ATOM   907  C C   . ALA A 1 129 ? 145.424 138.939 146.599 1.00 26.13  ? 203 ALA A C   1 
ATOM   908  O O   . ALA A 1 129 ? 145.598 137.792 147.018 1.00 33.43  ? 203 ALA A O   1 
ATOM   909  C CB  . ALA A 1 129 ? 145.358 139.011 144.104 1.00 26.68  ? 203 ALA A CB  1 
ATOM   910  N N   . PHE A 1 130 ? 144.613 139.813 147.190 1.00 28.17  ? 204 PHE A N   1 
ATOM   911  C CA  . PHE A 1 130 ? 143.829 139.506 148.377 1.00 11.83  ? 204 PHE A CA  1 
ATOM   912  C C   . PHE A 1 130 ? 142.351 139.706 148.079 1.00 17.51  ? 204 PHE A C   1 
ATOM   913  O O   . PHE A 1 130 ? 141.970 140.666 147.402 1.00 34.39  ? 204 PHE A O   1 
ATOM   914  C CB  . PHE A 1 130 ? 144.232 140.393 149.555 1.00 17.68  ? 204 PHE A CB  1 
ATOM   915  C CG  . PHE A 1 130 ? 145.345 139.836 150.388 1.00 17.90  ? 204 PHE A CG  1 
ATOM   916  C CD1 . PHE A 1 130 ? 145.118 138.784 151.256 1.00 23.88  ? 204 PHE A CD1 1 
ATOM   917  C CD2 . PHE A 1 130 ? 146.614 140.380 150.320 1.00 14.99  ? 204 PHE A CD2 1 
ATOM   918  C CE1 . PHE A 1 130 ? 146.140 138.275 152.028 1.00 20.47  ? 204 PHE A CE1 1 
ATOM   919  C CE2 . PHE A 1 130 ? 147.637 139.876 151.091 1.00 13.71  ? 204 PHE A CE2 1 
ATOM   920  C CZ  . PHE A 1 130 ? 147.399 138.823 151.946 1.00 11.65  ? 204 PHE A CZ  1 
ATOM   921  N N   . HIS A 1 131 ? 141.519 138.799 148.583 1.00 23.30  ? 205 HIS A N   1 
ATOM   922  C CA  . HIS A 1 131 ? 140.072 138.911 148.460 1.00 21.81  ? 205 HIS A CA  1 
ATOM   923  C C   . HIS A 1 131 ? 139.485 139.336 149.800 1.00 35.02  ? 205 HIS A C   1 
ATOM   924  O O   . HIS A 1 131 ? 139.769 138.722 150.834 1.00 45.74  ? 205 HIS A O   1 
ATOM   925  C CB  . HIS A 1 131 ? 139.454 137.596 147.970 1.00 22.72  ? 205 HIS A CB  1 
ATOM   926  C CG  . HIS A 1 131 ? 139.488 136.485 148.973 1.00 19.55  ? 205 HIS A CG  1 
ATOM   927  N ND1 . HIS A 1 131 ? 140.520 135.574 149.035 1.00 27.89  ? 205 HIS A ND1 1 
ATOM   928  C CD2 . HIS A 1 131 ? 138.607 136.122 149.934 1.00 30.69  ? 205 HIS A CD2 1 
ATOM   929  C CE1 . HIS A 1 131 ? 140.279 134.706 150.001 1.00 30.88  ? 205 HIS A CE1 1 
ATOM   930  N NE2 . HIS A 1 131 ? 139.126 135.017 150.564 1.00 33.15  ? 205 HIS A NE2 1 
ATOM   931  N N   . LEU A 1 132 ? 138.695 140.408 149.778 1.00 32.96  ? 206 LEU A N   1 
ATOM   932  C CA  . LEU A 1 132 ? 138.145 141.023 150.983 1.00 31.48  ? 206 LEU A CA  1 
ATOM   933  C C   . LEU A 1 132 ? 136.670 141.313 150.745 1.00 43.31  ? 206 LEU A C   1 
ATOM   934  O O   . LEU A 1 132 ? 136.329 142.245 150.009 1.00 42.71  ? 206 LEU A O   1 
ATOM   935  C CB  . LEU A 1 132 ? 138.892 142.308 151.336 1.00 34.47  ? 206 LEU A CB  1 
ATOM   936  C CG  . LEU A 1 132 ? 140.235 142.254 152.061 1.00 32.86  ? 206 LEU A CG  1 
ATOM   937  C CD1 . LEU A 1 132 ? 141.342 141.734 151.172 1.00 37.61  ? 206 LEU A CD1 1 
ATOM   938  C CD2 . LEU A 1 132 ? 140.571 143.645 152.533 1.00 41.16  ? 206 LEU A CD2 1 
ATOM   939  N N   . GLY A 1 133 ? 135.798 140.522 151.364 1.00 51.28  ? 207 GLY A N   1 
ATOM   940  C CA  . GLY A 1 133 ? 134.373 140.677 151.169 1.00 51.67  ? 207 GLY A CA  1 
ATOM   941  C C   . GLY A 1 133 ? 133.866 140.217 149.823 1.00 52.02  ? 207 GLY A C   1 
ATOM   942  O O   . GLY A 1 133 ? 132.658 140.303 149.571 1.00 52.36  ? 207 GLY A O   1 
ATOM   943  N N   . SER A 1 134 ? 134.748 139.733 148.954 1.00 46.65  ? 208 SER A N   1 
ATOM   944  C CA  . SER A 1 134 ? 134.377 139.188 147.659 1.00 42.90  ? 208 SER A CA  1 
ATOM   945  C C   . SER A 1 134 ? 135.153 137.899 147.448 1.00 38.97  ? 208 SER A C   1 
ATOM   946  O O   . SER A 1 134 ? 136.254 137.729 147.977 1.00 42.14  ? 208 SER A O   1 
ATOM   947  C CB  . SER A 1 134 ? 134.664 140.176 146.520 1.00 39.91  ? 208 SER A CB  1 
ATOM   948  O OG  . SER A 1 134 ? 136.040 140.177 146.184 1.00 42.12  ? 208 SER A OG  1 
ATOM   949  N N   . LEU A 1 135 ? 134.570 136.987 146.674 1.00 35.38  ? 209 LEU A N   1 
ATOM   950  C CA  . LEU A 1 135 ? 135.203 135.688 146.483 1.00 37.83  ? 209 LEU A CA  1 
ATOM   951  C C   . LEU A 1 135 ? 136.374 135.790 145.510 1.00 42.95  ? 209 LEU A C   1 
ATOM   952  O O   . LEU A 1 135 ? 137.524 135.527 145.876 1.00 44.84  ? 209 LEU A O   1 
ATOM   953  C CB  . LEU A 1 135 ? 134.167 134.671 146.003 1.00 41.09  ? 209 LEU A CB  1 
ATOM   954  C CG  . LEU A 1 135 ? 134.625 133.220 145.891 1.00 42.85  ? 209 LEU A CG  1 
ATOM   955  C CD1 . LEU A 1 135 ? 135.103 132.711 147.239 1.00 39.27  ? 209 LEU A CD1 1 
ATOM   956  C CD2 . LEU A 1 135 ? 133.476 132.375 145.390 1.00 42.06  ? 209 LEU A CD2 1 
ATOM   957  N N   . GLY A 1 136 ? 136.099 136.174 144.266 1.00 35.89  ? 210 GLY A N   1 
ATOM   958  C CA  . GLY A 1 136 ? 137.159 136.469 143.323 1.00 31.26  ? 210 GLY A CA  1 
ATOM   959  C C   . GLY A 1 136 ? 137.791 135.247 142.692 1.00 30.71  ? 210 GLY A C   1 
ATOM   960  O O   . GLY A 1 136 ? 138.081 134.263 143.379 1.00 40.78  ? 210 GLY A O   1 
ATOM   961  N N   . PHE A 1 137 ? 138.019 135.301 141.381 1.00 26.49  ? 211 PHE A N   1 
ATOM   962  C CA  . PHE A 1 137 ? 138.669 134.206 140.674 1.00 24.12  ? 211 PHE A CA  1 
ATOM   963  C C   . PHE A 1 137 ? 140.185 134.343 140.656 1.00 35.04  ? 211 PHE A C   1 
ATOM   964  O O   . PHE A 1 137 ? 140.891 133.331 140.727 1.00 34.72  ? 211 PHE A O   1 
ATOM   965  C CB  . PHE A 1 137 ? 138.140 134.124 139.239 1.00 28.94  ? 211 PHE A CB  1 
ATOM   966  C CG  . PHE A 1 137 ? 138.165 132.739 138.659 1.00 26.54  ? 211 PHE A CG  1 
ATOM   967  C CD1 . PHE A 1 137 ? 139.354 132.171 138.234 1.00 30.94  ? 211 PHE A CD1 1 
ATOM   968  C CD2 . PHE A 1 137 ? 136.999 132.005 138.538 1.00 26.88  ? 211 PHE A CD2 1 
ATOM   969  C CE1 . PHE A 1 137 ? 139.378 130.898 137.701 1.00 30.96  ? 211 PHE A CE1 1 
ATOM   970  C CE2 . PHE A 1 137 ? 137.017 130.732 138.006 1.00 33.81  ? 211 PHE A CE2 1 
ATOM   971  C CZ  . PHE A 1 137 ? 138.208 130.178 137.587 1.00 31.63  ? 211 PHE A CZ  1 
ATOM   972  N N   . LEU A 1 138 ? 140.699 135.568 140.569 1.00 35.61  ? 212 LEU A N   1 
ATOM   973  C CA  . LEU A 1 138 ? 142.132 135.825 140.533 1.00 29.21  ? 212 LEU A CA  1 
ATOM   974  C C   . LEU A 1 138 ? 142.678 136.298 141.875 1.00 35.63  ? 212 LEU A C   1 
ATOM   975  O O   . LEU A 1 138 ? 143.813 136.780 141.934 1.00 39.90  ? 212 LEU A O   1 
ATOM   976  C CB  . LEU A 1 138 ? 142.453 136.855 139.449 1.00 30.05  ? 212 LEU A CB  1 
ATOM   977  C CG  . LEU A 1 138 ? 141.851 136.609 138.064 1.00 26.76  ? 212 LEU A CG  1 
ATOM   978  C CD1 . LEU A 1 138 ? 142.246 137.716 137.103 1.00 29.04  ? 212 LEU A CD1 1 
ATOM   979  C CD2 . LEU A 1 138 ? 142.277 135.252 137.528 1.00 35.87  ? 212 LEU A CD2 1 
ATOM   980  N N   . THR A 1 139 ? 141.899 136.174 142.951 1.00 37.79  ? 213 THR A N   1 
ATOM   981  C CA  . THR A 1 139 ? 142.295 136.613 144.289 1.00 30.27  ? 213 THR A CA  1 
ATOM   982  C C   . THR A 1 139 ? 142.261 135.410 145.221 1.00 28.54  ? 213 THR A C   1 
ATOM   983  O O   . THR A 1 139 ? 141.226 135.121 145.843 1.00 38.93  ? 213 THR A O   1 
ATOM   984  C CB  . THR A 1 139 ? 141.382 137.728 144.795 1.00 31.36  ? 213 THR A CB  1 
ATOM   985  O OG1 . THR A 1 139 ? 140.029 137.257 144.834 1.00 38.79  ? 213 THR A OG1 1 
ATOM   986  C CG2 . THR A 1 139 ? 141.466 138.940 143.882 1.00 29.98  ? 213 THR A CG2 1 
ATOM   987  N N   . PRO A 1 140 ? 143.370 134.676 145.350 1.00 18.57  ? 214 PRO A N   1 
ATOM   988  C CA  . PRO A 1 140 ? 143.359 133.428 146.121 1.00 18.34  ? 214 PRO A CA  1 
ATOM   989  C C   . PRO A 1 140 ? 143.748 133.546 147.586 1.00 24.94  ? 214 PRO A C   1 
ATOM   990  O O   . PRO A 1 140 ? 143.620 132.550 148.312 1.00 31.54  ? 214 PRO A O   1 
ATOM   991  C CB  . PRO A 1 140 ? 144.390 132.580 145.368 1.00 23.39  ? 214 PRO A CB  1 
ATOM   992  C CG  . PRO A 1 140 ? 145.399 133.585 144.928 1.00 24.27  ? 214 PRO A CG  1 
ATOM   993  C CD  . PRO A 1 140 ? 144.623 134.840 144.593 1.00 23.52  ? 214 PRO A CD  1 
ATOM   994  N N   . PHE A 1 141 ? 144.210 134.704 148.047 1.00 28.82  ? 215 PHE A N   1 
ATOM   995  C CA  . PHE A 1 141 ? 144.729 134.852 149.401 1.00 21.15  ? 215 PHE A CA  1 
ATOM   996  C C   . PHE A 1 141 ? 143.651 135.397 150.328 1.00 27.48  ? 215 PHE A C   1 
ATOM   997  O O   . PHE A 1 141 ? 143.006 136.404 150.017 1.00 36.78  ? 215 PHE A O   1 
ATOM   998  C CB  . PHE A 1 141 ? 145.947 135.776 149.417 1.00 16.34  ? 215 PHE A CB  1 
ATOM   999  C CG  . PHE A 1 141 ? 147.234 135.090 149.065 1.00 16.71  ? 215 PHE A CG  1 
ATOM   1000 C CD1 . PHE A 1 141 ? 147.894 134.309 149.995 1.00 30.16  ? 215 PHE A CD1 1 
ATOM   1001 C CD2 . PHE A 1 141 ? 147.783 135.228 147.803 1.00 22.18  ? 215 PHE A CD2 1 
ATOM   1002 C CE1 . PHE A 1 141 ? 149.079 133.678 149.673 1.00 27.00  ? 215 PHE A CE1 1 
ATOM   1003 C CE2 . PHE A 1 141 ? 148.967 134.600 147.476 1.00 25.17  ? 215 PHE A CE2 1 
ATOM   1004 C CZ  . PHE A 1 141 ? 149.615 133.824 148.412 1.00 23.10  ? 215 PHE A CZ  1 
ATOM   1005 N N   . SER A 1 142 ? 143.461 134.728 151.462 1.00 27.68  ? 216 SER A N   1 
ATOM   1006 C CA  . SER A 1 142 ? 142.570 135.206 152.508 1.00 30.64  ? 216 SER A CA  1 
ATOM   1007 C C   . SER A 1 142 ? 143.332 136.137 153.440 1.00 37.60  ? 216 SER A C   1 
ATOM   1008 O O   . SER A 1 142 ? 144.501 135.897 153.757 1.00 40.61  ? 216 SER A O   1 
ATOM   1009 C CB  . SER A 1 142 ? 141.983 134.035 153.297 1.00 37.88  ? 216 SER A CB  1 
ATOM   1010 O OG  . SER A 1 142 ? 142.978 133.070 153.592 1.00 34.65  ? 216 SER A OG  1 
ATOM   1011 N N   . PHE A 1 143 ? 142.663 137.206 153.878 1.00 34.27  ? 217 PHE A N   1 
ATOM   1012 C CA  . PHE A 1 143 ? 143.342 138.207 154.691 1.00 27.86  ? 217 PHE A CA  1 
ATOM   1013 C C   . PHE A 1 143 ? 143.676 137.706 156.089 1.00 28.28  ? 217 PHE A C   1 
ATOM   1014 O O   . PHE A 1 143 ? 144.516 138.313 156.762 1.00 42.02  ? 217 PHE A O   1 
ATOM   1015 C CB  . PHE A 1 143 ? 142.503 139.479 154.793 1.00 29.57  ? 217 PHE A CB  1 
ATOM   1016 C CG  . PHE A 1 143 ? 143.293 140.683 155.212 1.00 29.25  ? 217 PHE A CG  1 
ATOM   1017 C CD1 . PHE A 1 143 ? 144.233 141.239 154.362 1.00 32.30  ? 217 PHE A CD1 1 
ATOM   1018 C CD2 . PHE A 1 143 ? 143.116 141.244 156.464 1.00 33.76  ? 217 PHE A CD2 1 
ATOM   1019 C CE1 . PHE A 1 143 ? 144.969 142.340 154.747 1.00 33.76  ? 217 PHE A CE1 1 
ATOM   1020 C CE2 . PHE A 1 143 ? 143.852 142.345 156.855 1.00 34.81  ? 217 PHE A CE2 1 
ATOM   1021 C CZ  . PHE A 1 143 ? 144.779 142.893 155.995 1.00 35.84  ? 217 PHE A CZ  1 
ATOM   1022 N N   . GLU A 1 144 ? 143.044 136.629 156.545 1.00 34.08  ? 218 GLU A N   1 
ATOM   1023 C CA  . GLU A 1 144 ? 143.366 136.087 157.856 1.00 31.29  ? 218 GLU A CA  1 
ATOM   1024 C C   . GLU A 1 144 ? 144.791 135.548 157.871 1.00 28.32  ? 218 GLU A C   1 
ATOM   1025 O O   . GLU A 1 144 ? 145.237 134.896 156.923 1.00 43.75  ? 218 GLU A O   1 
ATOM   1026 C CB  . GLU A 1 144 ? 142.370 134.991 158.243 1.00 40.66  ? 218 GLU A CB  1 
ATOM   1027 C CG  . GLU A 1 144 ? 142.412 133.746 157.371 1.00 44.37  ? 218 GLU A CG  1 
ATOM   1028 C CD  . GLU A 1 144 ? 141.362 132.724 157.761 1.00 47.23  ? 218 GLU A CD  1 
ATOM   1029 O OE1 . GLU A 1 144 ? 140.584 132.998 158.700 1.00 46.39  ? 218 GLU A OE1 1 
ATOM   1030 O OE2 . GLU A 1 144 ? 141.314 131.648 157.129 1.00 47.50  ? 218 GLU A OE2 1 
ATOM   1031 N N   . ASN A 1 145 ? 145.511 135.845 158.955 1.00 31.06  ? 219 ASN A N   1 
ATOM   1032 C CA  . ASN A 1 145 ? 146.902 135.421 159.122 1.00 31.89  ? 219 ASN A CA  1 
ATOM   1033 C C   . ASN A 1 145 ? 147.766 135.878 157.949 1.00 40.71  ? 219 ASN A C   1 
ATOM   1034 O O   . ASN A 1 145 ? 148.604 135.132 157.438 1.00 44.73  ? 219 ASN A O   1 
ATOM   1035 C CB  . ASN A 1 145 ? 146.996 133.906 159.312 1.00 30.44  ? 219 ASN A CB  1 
ATOM   1036 C CG  . ASN A 1 145 ? 148.146 133.502 160.210 1.00 38.94  ? 219 ASN A CG  1 
ATOM   1037 O OD1 . ASN A 1 145 ? 149.227 134.086 160.155 1.00 40.22  ? 219 ASN A OD1 1 
ATOM   1038 N ND2 . ASN A 1 145 ? 147.918 132.495 161.045 1.00 40.94  ? 219 ASN A ND2 1 
ATOM   1039 N N   . PHE A 1 146 ? 147.559 137.124 157.517 1.00 38.17  ? 220 PHE A N   1 
ATOM   1040 C CA  . PHE A 1 146 ? 148.293 137.640 156.368 1.00 24.53  ? 220 PHE A CA  1 
ATOM   1041 C C   . PHE A 1 146 ? 149.762 137.889 156.677 1.00 30.54  ? 220 PHE A C   1 
ATOM   1042 O O   . PHE A 1 146 ? 150.569 137.973 155.745 1.00 45.63  ? 220 PHE A O   1 
ATOM   1043 C CB  . PHE A 1 146 ? 147.639 138.924 155.851 1.00 25.68  ? 220 PHE A CB  1 
ATOM   1044 C CG  . PHE A 1 146 ? 147.929 140.142 156.684 1.00 31.97  ? 220 PHE A CG  1 
ATOM   1045 C CD1 . PHE A 1 146 ? 147.177 140.421 157.812 1.00 37.30  ? 220 PHE A CD1 1 
ATOM   1046 C CD2 . PHE A 1 146 ? 148.940 141.018 156.327 1.00 35.38  ? 220 PHE A CD2 1 
ATOM   1047 C CE1 . PHE A 1 146 ? 147.437 141.542 158.573 1.00 35.79  ? 220 PHE A CE1 1 
ATOM   1048 C CE2 . PHE A 1 146 ? 149.205 142.139 157.086 1.00 34.75  ? 220 PHE A CE2 1 
ATOM   1049 C CZ  . PHE A 1 146 ? 148.452 142.401 158.208 1.00 34.61  ? 220 PHE A CZ  1 
ATOM   1050 N N   . GLN A 1 147 ? 150.125 138.003 157.957 1.00 28.87  ? 221 GLN A N   1 
ATOM   1051 C CA  . GLN A 1 147 ? 151.519 138.247 158.315 1.00 27.78  ? 221 GLN A CA  1 
ATOM   1052 C C   . GLN A 1 147 ? 152.412 137.104 157.850 1.00 38.47  ? 221 GLN A C   1 
ATOM   1053 O O   . GLN A 1 147 ? 153.445 137.327 157.207 1.00 44.09  ? 221 GLN A O   1 
ATOM   1054 C CB  . GLN A 1 147 ? 151.643 138.438 159.827 1.00 33.57  ? 221 GLN A CB  1 
ATOM   1055 C CG  . GLN A 1 147 ? 151.412 139.857 160.311 1.00 35.26  ? 221 GLN A CG  1 
ATOM   1056 C CD  . GLN A 1 147 ? 149.995 140.085 160.795 1.00 37.58  ? 221 GLN A CD  1 
ATOM   1057 O OE1 . GLN A 1 147 ? 149.242 139.138 161.016 1.00 41.78  ? 221 GLN A OE1 1 
ATOM   1058 N NE2 . GLN A 1 147 ? 149.628 141.348 160.978 1.00 37.11  ? 221 GLN A NE2 1 
ATOM   1059 N N   . SER A 1 148 ? 152.021 135.866 158.159 1.00 34.84  ? 222 SER A N   1 
ATOM   1060 C CA  . SER A 1 148 ? 152.828 134.716 157.767 1.00 32.83  ? 222 SER A CA  1 
ATOM   1061 C C   . SER A 1 148 ? 152.900 134.585 156.252 1.00 43.10  ? 222 SER A C   1 
ATOM   1062 O O   . SER A 1 148 ? 153.958 134.263 155.700 1.00 47.59  ? 222 SER A O   1 
ATOM   1063 C CB  . SER A 1 148 ? 152.262 133.441 158.391 1.00 38.77  ? 222 SER A CB  1 
ATOM   1064 O OG  . SER A 1 148 ? 152.806 132.287 157.775 1.00 46.84  ? 222 SER A OG  1 
ATOM   1065 N N   . GLN A 1 149 ? 151.786 134.839 155.562 1.00 37.91  ? 223 GLN A N   1 
ATOM   1066 C CA  . GLN A 1 149 ? 151.769 134.718 154.108 1.00 31.37  ? 223 GLN A CA  1 
ATOM   1067 C C   . GLN A 1 149 ? 152.687 135.746 153.455 1.00 37.50  ? 223 GLN A C   1 
ATOM   1068 O O   . GLN A 1 149 ? 153.481 135.412 152.565 1.00 44.61  ? 223 GLN A O   1 
ATOM   1069 C CB  . GLN A 1 149 ? 150.337 134.864 153.593 1.00 31.37  ? 223 GLN A CB  1 
ATOM   1070 C CG  . GLN A 1 149 ? 149.506 133.600 153.726 1.00 30.72  ? 223 GLN A CG  1 
ATOM   1071 C CD  . GLN A 1 149 ? 148.018 133.871 153.664 1.00 30.74  ? 223 GLN A CD  1 
ATOM   1072 O OE1 . GLN A 1 149 ? 147.584 135.022 153.695 1.00 39.86  ? 223 GLN A OE1 1 
ATOM   1073 N NE2 . GLN A 1 149 ? 147.226 132.810 153.573 1.00 32.22  ? 223 GLN A NE2 1 
ATOM   1074 N N   . VAL A 1 150 ? 152.598 137.006 153.890 1.00 30.64  ? 224 VAL A N   1 
ATOM   1075 C CA  . VAL A 1 150 ? 153.442 138.036 153.293 1.00 24.77  ? 224 VAL A CA  1 
ATOM   1076 C C   . VAL A 1 150 ? 154.905 137.792 153.641 1.00 34.01  ? 224 VAL A C   1 
ATOM   1077 O O   . VAL A 1 150 ? 155.795 138.028 152.816 1.00 44.65  ? 224 VAL A O   1 
ATOM   1078 C CB  . VAL A 1 150 ? 152.970 139.445 153.707 1.00 20.65  ? 224 VAL A CB  1 
ATOM   1079 C CG1 . VAL A 1 150 ? 153.179 139.694 155.190 1.00 37.07  ? 224 VAL A CG1 1 
ATOM   1080 C CG2 . VAL A 1 150 ? 153.682 140.505 152.881 1.00 31.12  ? 224 VAL A CG2 1 
ATOM   1081 N N   . THR A 1 151 ? 155.183 137.290 154.849 1.00 30.57  ? 225 THR A N   1 
ATOM   1082 C CA  . THR A 1 151 ? 156.561 136.969 155.204 1.00 33.79  ? 225 THR A CA  1 
ATOM   1083 C C   . THR A 1 151 ? 157.106 135.842 154.335 1.00 41.86  ? 225 THR A C   1 
ATOM   1084 O O   . THR A 1 151 ? 158.248 135.909 153.864 1.00 46.94  ? 225 THR A O   1 
ATOM   1085 C CB  . THR A 1 151 ? 156.650 136.598 156.684 1.00 37.75  ? 225 THR A CB  1 
ATOM   1086 O OG1 . THR A 1 151 ? 155.867 137.517 157.455 1.00 43.28  ? 225 THR A OG1 1 
ATOM   1087 C CG2 . THR A 1 151 ? 158.094 136.649 157.157 1.00 40.78  ? 225 THR A CG2 1 
ATOM   1088 N N   . GLN A 1 152 ? 156.301 134.802 154.104 1.00 40.98  ? 226 GLN A N   1 
ATOM   1089 C CA  . GLN A 1 152 ? 156.739 133.695 153.261 1.00 37.86  ? 226 GLN A CA  1 
ATOM   1090 C C   . GLN A 1 152 ? 156.986 134.157 151.832 1.00 39.00  ? 226 GLN A C   1 
ATOM   1091 O O   . GLN A 1 152 ? 157.937 133.707 151.181 1.00 41.77  ? 226 GLN A O   1 
ATOM   1092 C CB  . GLN A 1 152 ? 155.704 132.571 153.290 1.00 35.26  ? 226 GLN A CB  1 
ATOM   1093 C CG  . GLN A 1 152 ? 155.847 131.624 154.468 1.00 44.21  ? 226 GLN A CG  1 
ATOM   1094 C CD  . GLN A 1 152 ? 157.291 131.258 154.748 1.00 50.81  ? 226 GLN A CD  1 
ATOM   1095 O OE1 . GLN A 1 152 ? 157.926 130.549 153.968 1.00 54.12  ? 226 GLN A OE1 1 
ATOM   1096 N NE2 . GLN A 1 152 ? 157.818 131.741 155.867 1.00 48.16  ? 226 GLN A NE2 1 
ATOM   1097 N N   . VAL A 1 153 ? 156.137 135.051 151.324 1.00 38.02  ? 227 VAL A N   1 
ATOM   1098 C CA  . VAL A 1 153 ? 156.347 135.580 149.980 1.00 32.09  ? 227 VAL A CA  1 
ATOM   1099 C C   . VAL A 1 153 ? 157.617 136.422 149.924 1.00 36.72  ? 227 VAL A C   1 
ATOM   1100 O O   . VAL A 1 153 ? 158.380 136.355 148.953 1.00 47.32  ? 227 VAL A O   1 
ATOM   1101 C CB  . VAL A 1 153 ? 155.109 136.370 149.521 1.00 29.06  ? 227 VAL A CB  1 
ATOM   1102 C CG1 . VAL A 1 153 ? 155.426 137.184 148.281 1.00 32.85  ? 227 VAL A CG1 1 
ATOM   1103 C CG2 . VAL A 1 153 ? 153.961 135.414 149.248 1.00 39.62  ? 227 VAL A CG2 1 
ATOM   1104 N N   . ILE A 1 154 ? 157.870 137.221 150.964 1.00 37.41  ? 228 ILE A N   1 
ATOM   1105 C CA  . ILE A 1 154 ? 159.076 138.045 151.000 1.00 33.77  ? 228 ILE A CA  1 
ATOM   1106 C C   . ILE A 1 154 ? 160.324 137.170 151.023 1.00 35.91  ? 228 ILE A C   1 
ATOM   1107 O O   . ILE A 1 154 ? 161.319 137.468 150.349 1.00 40.05  ? 228 ILE A O   1 
ATOM   1108 C CB  . ILE A 1 154 ? 159.031 139.004 152.203 1.00 34.54  ? 228 ILE A CB  1 
ATOM   1109 C CG1 . ILE A 1 154 ? 158.001 140.108 151.967 1.00 37.53  ? 228 ILE A CG1 1 
ATOM   1110 C CG2 . ILE A 1 154 ? 160.401 139.611 152.464 1.00 43.00  ? 228 ILE A CG2 1 
ATOM   1111 C CD1 . ILE A 1 154 ? 157.672 140.900 153.207 1.00 39.02  ? 228 ILE A CD1 1 
ATOM   1112 N N   . GLU A 1 155 ? 160.295 136.081 151.796 1.00 37.65  ? 229 GLU A N   1 
ATOM   1113 C CA  . GLU A 1 155 ? 161.461 135.204 151.875 1.00 39.81  ? 229 GLU A CA  1 
ATOM   1114 C C   . GLU A 1 155 ? 161.805 134.609 150.515 1.00 43.47  ? 229 GLU A C   1 
ATOM   1115 O O   . GLU A 1 155 ? 162.980 134.550 150.135 1.00 43.12  ? 229 GLU A O   1 
ATOM   1116 C CB  . GLU A 1 155 ? 161.225 134.095 152.900 1.00 39.82  ? 229 GLU A CB  1 
ATOM   1117 C CG  . GLU A 1 155 ? 161.025 134.589 154.321 1.00 45.94  ? 229 GLU A CG  1 
ATOM   1118 C CD  . GLU A 1 155 ? 162.071 135.603 154.738 1.00 50.33  ? 229 GLU A CD  1 
ATOM   1119 O OE1 . GLU A 1 155 ? 163.270 135.254 154.747 1.00 48.90  ? 229 GLU A OE1 1 
ATOM   1120 O OE2 . GLU A 1 155 ? 161.695 136.750 155.059 1.00 49.80  ? 229 GLU A OE2 1 
ATOM   1121 N N   . GLY A 1 156 ? 160.798 134.164 149.768 1.00 48.84  ? 230 GLY A N   1 
ATOM   1122 C CA  . GLY A 1 156 ? 161.033 133.643 148.437 1.00 43.71  ? 230 GLY A CA  1 
ATOM   1123 C C   . GLY A 1 156 ? 160.577 132.213 148.239 1.00 37.34  ? 230 GLY A C   1 
ATOM   1124 O O   . GLY A 1 156 ? 161.044 131.529 147.324 1.00 40.27  ? 230 GLY A O   1 
ATOM   1125 N N   . ASN A 1 157 ? 159.667 131.747 149.087 1.00 41.56  ? 231 ASN A N   1 
ATOM   1126 C CA  . ASN A 1 157 ? 159.110 130.400 148.996 1.00 47.22  ? 231 ASN A CA  1 
ATOM   1127 C C   . ASN A 1 157 ? 157.648 130.531 148.574 1.00 52.45  ? 231 ASN A C   1 
ATOM   1128 O O   . ASN A 1 157 ? 156.745 130.558 149.412 1.00 58.47  ? 231 ASN A O   1 
ATOM   1129 C CB  . ASN A 1 157 ? 159.249 129.656 150.322 1.00 49.89  ? 231 ASN A CB  1 
ATOM   1130 C CG  . ASN A 1 157 ? 160.679 129.623 150.825 1.00 53.93  ? 231 ASN A CG  1 
ATOM   1131 O OD1 . ASN A 1 157 ? 161.616 129.928 150.088 1.00 57.71  ? 231 ASN A OD1 1 
ATOM   1132 N ND2 . ASN A 1 157 ? 160.853 129.252 152.087 1.00 52.39  ? 231 ASN A ND2 1 
ATOM   1133 N N   . ALA A 1 158 ? 157.422 130.605 147.265 1.00 45.15  ? 232 ALA A N   1 
ATOM   1134 C CA  . ALA A 1 158 ? 156.078 130.758 146.729 1.00 41.53  ? 232 ALA A CA  1 
ATOM   1135 C C   . ALA A 1 158 ? 156.087 130.402 145.251 1.00 43.74  ? 232 ALA A C   1 
ATOM   1136 O O   . ALA A 1 158 ? 157.055 130.680 144.539 1.00 48.65  ? 232 ALA A O   1 
ATOM   1137 C CB  . ALA A 1 158 ? 155.551 132.182 146.931 1.00 39.77  ? 232 ALA A CB  1 
ATOM   1138 N N   . ALA A 1 159 ? 154.999 129.786 144.801 1.00 37.45  ? 233 ALA A N   1 
ATOM   1139 C CA  . ALA A 1 159 ? 154.836 129.430 143.400 1.00 36.01  ? 233 ALA A CA  1 
ATOM   1140 C C   . ALA A 1 159 ? 154.115 130.544 142.651 1.00 34.04  ? 233 ALA A C   1 
ATOM   1141 O O   . ALA A 1 159 ? 153.327 131.299 143.227 1.00 42.52  ? 233 ALA A O   1 
ATOM   1142 C CB  . ALA A 1 159 ? 154.067 128.117 143.258 1.00 34.03  ? 233 ALA A CB  1 
ATOM   1143 N N   . VAL A 1 160 ? 154.394 130.639 141.354 1.00 30.72  ? 234 VAL A N   1 
ATOM   1144 C CA  . VAL A 1 160 ? 153.918 131.734 140.518 1.00 27.35  ? 234 VAL A CA  1 
ATOM   1145 C C   . VAL A 1 160 ? 153.255 131.165 139.271 1.00 32.13  ? 234 VAL A C   1 
ATOM   1146 O O   . VAL A 1 160 ? 153.760 130.212 138.668 1.00 45.11  ? 234 VAL A O   1 
ATOM   1147 C CB  . VAL A 1 160 ? 155.071 132.686 140.134 1.00 27.10  ? 234 VAL A CB  1 
ATOM   1148 C CG1 . VAL A 1 160 ? 154.599 133.726 139.142 1.00 31.09  ? 234 VAL A CG1 1 
ATOM   1149 C CG2 . VAL A 1 160 ? 155.640 133.358 141.372 1.00 35.84  ? 234 VAL A CG2 1 
ATOM   1150 N N   . VAL A 1 161 ? 152.123 131.751 138.889 1.00 24.24  ? 235 VAL A N   1 
ATOM   1151 C CA  . VAL A 1 161 ? 151.436 131.429 137.643 1.00 17.16  ? 235 VAL A CA  1 
ATOM   1152 C C   . VAL A 1 161 ? 151.646 132.595 136.688 1.00 23.25  ? 235 VAL A C   1 
ATOM   1153 O O   . VAL A 1 161 ? 151.198 133.716 136.959 1.00 30.59  ? 235 VAL A O   1 
ATOM   1154 C CB  . VAL A 1 161 ? 149.940 131.168 137.869 1.00 20.61  ? 235 VAL A CB  1 
ATOM   1155 C CG1 . VAL A 1 161 ? 149.284 130.693 136.583 1.00 26.08  ? 235 VAL A CG1 1 
ATOM   1156 C CG2 . VAL A 1 161 ? 149.736 130.167 138.990 1.00 31.36  ? 235 VAL A CG2 1 
ATOM   1157 N N   . LEU A 1 162 ? 152.326 132.336 135.572 1.00 22.71  ? 236 LEU A N   1 
ATOM   1158 C CA  . LEU A 1 162 ? 152.625 133.372 134.583 1.00 21.06  ? 236 LEU A CA  1 
ATOM   1159 C C   . LEU A 1 162 ? 151.431 133.507 133.647 1.00 26.47  ? 236 LEU A C   1 
ATOM   1160 O O   . LEU A 1 162 ? 151.293 132.775 132.667 1.00 34.32  ? 236 LEU A O   1 
ATOM   1161 C CB  . LEU A 1 162 ? 153.901 133.039 133.822 1.00 25.59  ? 236 LEU A CB  1 
ATOM   1162 C CG  . LEU A 1 162 ? 155.196 133.053 134.634 1.00 28.68  ? 236 LEU A CG  1 
ATOM   1163 C CD1 . LEU A 1 162 ? 156.360 132.557 133.793 1.00 33.57  ? 236 LEU A CD1 1 
ATOM   1164 C CD2 . LEU A 1 162 ? 155.474 134.447 135.169 1.00 32.93  ? 236 LEU A CD2 1 
ATOM   1165 N N   . ARG A 1 163 ? 150.557 134.463 133.952 1.00 27.65  ? 237 ARG A N   1 
ATOM   1166 C CA  . ARG A 1 163 ? 149.372 134.698 133.139 1.00 21.90  ? 237 ARG A CA  1 
ATOM   1167 C C   . ARG A 1 163 ? 149.733 135.515 131.905 1.00 28.59  ? 237 ARG A C   1 
ATOM   1168 O O   . ARG A 1 163 ? 150.317 136.597 132.015 1.00 35.50  ? 237 ARG A O   1 
ATOM   1169 C CB  . ARG A 1 163 ? 148.302 135.423 133.952 1.00 21.93  ? 237 ARG A CB  1 
ATOM   1170 C CG  . ARG A 1 163 ? 148.090 134.860 135.342 1.00 19.99  ? 237 ARG A CG  1 
ATOM   1171 C CD  . ARG A 1 163 ? 146.815 135.400 135.957 1.00 21.49  ? 237 ARG A CD  1 
ATOM   1172 N NE  . ARG A 1 163 ? 146.367 134.587 137.080 1.00 22.75  ? 237 ARG A NE  1 
ATOM   1173 C CZ  . ARG A 1 163 ? 145.422 133.661 137.002 1.00 21.43  ? 237 ARG A CZ  1 
ATOM   1174 N NH1 . ARG A 1 163 ? 144.802 133.400 135.863 1.00 26.41  ? 237 ARG A NH1 1 
ATOM   1175 N NH2 . ARG A 1 163 ? 145.091 132.978 138.094 1.00 22.43  ? 237 ARG A NH2 1 
ATOM   1176 N N   . SER A 1 164 ? 149.377 134.999 130.733 1.00 30.53  ? 238 SER A N   1 
ATOM   1177 C CA  . SER A 1 164 ? 149.670 135.692 129.491 1.00 19.49  ? 238 SER A CA  1 
ATOM   1178 C C   . SER A 1 164 ? 148.747 136.895 129.311 1.00 28.55  ? 238 SER A C   1 
ATOM   1179 O O   . SER A 1 164 ? 147.647 136.961 129.864 1.00 34.92  ? 238 SER A O   1 
ATOM   1180 C CB  . SER A 1 164 ? 149.532 134.743 128.301 1.00 28.62  ? 238 SER A CB  1 
ATOM   1181 O OG  . SER A 1 164 ? 148.188 134.326 128.135 1.00 37.77  ? 238 SER A OG  1 
ATOM   1182 N N   . ARG A 1 165 ? 149.217 137.855 128.519 1.00 25.30  ? 239 ARG A N   1 
ATOM   1183 C CA  . ARG A 1 165 ? 148.460 139.054 128.196 1.00 23.39  ? 239 ARG A CA  1 
ATOM   1184 C C   . ARG A 1 165 ? 148.478 139.267 126.690 1.00 26.92  ? 239 ARG A C   1 
ATOM   1185 O O   . ARG A 1 165 ? 149.353 138.762 125.982 1.00 35.01  ? 239 ARG A O   1 
ATOM   1186 C CB  . ARG A 1 165 ? 149.025 140.292 128.905 1.00 29.78  ? 239 ARG A CB  1 
ATOM   1187 C CG  . ARG A 1 165 ? 149.039 140.198 130.419 1.00 26.96  ? 239 ARG A CG  1 
ATOM   1188 C CD  . ARG A 1 165 ? 149.317 141.552 131.046 1.00 28.94  ? 239 ARG A CD  1 
ATOM   1189 N NE  . ARG A 1 165 ? 150.636 142.059 130.689 1.00 27.40  ? 239 ARG A NE  1 
ATOM   1190 C CZ  . ARG A 1 165 ? 151.117 143.233 131.073 1.00 24.10  ? 239 ARG A CZ  1 
ATOM   1191 N NH1 . ARG A 1 165 ? 150.411 144.054 131.831 1.00 23.45  ? 239 ARG A NH1 1 
ATOM   1192 N NH2 . ARG A 1 165 ? 152.338 143.591 130.687 1.00 34.18  ? 239 ARG A NH2 1 
ATOM   1193 N N   . LEU A 1 166 ? 147.499 140.022 126.201 1.00 30.15  ? 240 LEU A N   1 
ATOM   1194 C CA  . LEU A 1 166 ? 147.405 140.340 124.783 1.00 21.48  ? 240 LEU A CA  1 
ATOM   1195 C C   . LEU A 1 166 ? 147.884 141.763 124.536 1.00 25.79  ? 240 LEU A C   1 
ATOM   1196 O O   . LEU A 1 166 ? 147.459 142.698 125.223 1.00 35.62  ? 240 LEU A O   1 
ATOM   1197 C CB  . LEU A 1 166 ? 145.976 140.176 124.264 1.00 21.79  ? 240 LEU A CB  1 
ATOM   1198 C CG  . LEU A 1 166 ? 145.411 138.763 124.132 1.00 28.54  ? 240 LEU A CG  1 
ATOM   1199 C CD1 . LEU A 1 166 ? 143.903 138.809 123.954 1.00 29.37  ? 240 LEU A CD1 1 
ATOM   1200 C CD2 . LEU A 1 166 ? 146.070 138.021 122.983 1.00 27.85  ? 240 LEU A CD2 1 
ATOM   1201 N N   . LYS A 1 167 ? 148.767 141.916 123.555 1.00 27.57  ? 241 LYS A N   1 
ATOM   1202 C CA  . LYS A 1 167 ? 149.226 143.221 123.103 1.00 25.05  ? 241 LYS A CA  1 
ATOM   1203 C C   . LYS A 1 167 ? 148.373 143.644 121.915 1.00 32.26  ? 241 LYS A C   1 
ATOM   1204 O O   . LYS A 1 167 ? 148.313 142.935 120.902 1.00 37.73  ? 241 LYS A O   1 
ATOM   1205 C CB  . LYS A 1 167 ? 150.704 143.170 122.723 1.00 27.52  ? 241 LYS A CB  1 
ATOM   1206 C CG  . LYS A 1 167 ? 151.298 144.503 122.312 1.00 30.74  ? 241 LYS A CG  1 
ATOM   1207 C CD  . LYS A 1 167 ? 152.686 144.315 121.724 1.00 32.07  ? 241 LYS A CD  1 
ATOM   1208 C CE  . LYS A 1 167 ? 152.657 144.350 120.207 1.00 34.27  ? 241 LYS A CE  1 
ATOM   1209 N NZ  . LYS A 1 167 ? 152.676 145.744 119.692 1.00 35.79  ? 241 LYS A NZ  1 
ATOM   1210 N N   . VAL A 1 168 ? 147.708 144.790 122.041 1.00 28.58  ? 242 VAL A N   1 
ATOM   1211 C CA  . VAL A 1 168 ? 146.759 145.263 121.042 1.00 19.15  ? 242 VAL A CA  1 
ATOM   1212 C C   . VAL A 1 168 ? 147.158 146.666 120.601 1.00 27.41  ? 242 VAL A C   1 
ATOM   1213 O O   . VAL A 1 168 ? 147.480 147.520 121.434 1.00 40.42  ? 242 VAL A O   1 
ATOM   1214 C CB  . VAL A 1 168 ? 145.312 145.232 121.577 1.00 26.00  ? 242 VAL A CB  1 
ATOM   1215 C CG1 . VAL A 1 168 ? 145.170 146.088 122.820 1.00 35.33  ? 242 VAL A CG1 1 
ATOM   1216 C CG2 . VAL A 1 168 ? 144.344 145.693 120.510 1.00 30.89  ? 242 VAL A CG2 1 
ATOM   1217 N N   . ARG A 1 169 ? 147.167 146.887 119.291 1.00 30.70  ? 243 ARG A N   1 
ATOM   1218 C CA  . ARG A 1 169 ? 147.436 148.189 118.699 1.00 31.87  ? 243 ARG A CA  1 
ATOM   1219 C C   . ARG A 1 169 ? 146.231 148.623 117.881 1.00 36.27  ? 243 ARG A C   1 
ATOM   1220 O O   . ARG A 1 169 ? 145.694 147.835 117.095 1.00 38.52  ? 243 ARG A O   1 
ATOM   1221 C CB  . ARG A 1 169 ? 148.683 148.158 117.813 1.00 35.37  ? 243 ARG A CB  1 
ATOM   1222 C CG  . ARG A 1 169 ? 149.821 147.311 118.347 1.00 39.07  ? 243 ARG A CG  1 
ATOM   1223 C CD  . ARG A 1 169 ? 150.829 146.992 117.252 1.00 40.54  ? 243 ARG A CD  1 
ATOM   1224 N NE  . ARG A 1 169 ? 151.739 148.103 116.998 1.00 41.66  ? 243 ARG A NE  1 
ATOM   1225 C CZ  . ARG A 1 169 ? 151.565 149.017 116.054 1.00 45.24  ? 243 ARG A CZ  1 
ATOM   1226 N NH1 . ARG A 1 169 ? 150.524 148.980 115.238 1.00 41.62  ? 243 ARG A NH1 1 
ATOM   1227 N NH2 . ARG A 1 169 ? 152.460 149.992 115.921 1.00 44.28  ? 243 ARG A NH2 1 
ATOM   1228 N N   . VAL A 1 170 ? 145.810 149.870 118.061 1.00 38.71  ? 244 VAL A N   1 
ATOM   1229 C CA  . VAL A 1 170 ? 144.706 150.448 117.306 1.00 33.92  ? 244 VAL A CA  1 
ATOM   1230 C C   . VAL A 1 170 ? 145.293 151.436 116.310 1.00 39.52  ? 244 VAL A C   1 
ATOM   1231 O O   . VAL A 1 170 ? 145.939 152.415 116.704 1.00 43.88  ? 244 VAL A O   1 
ATOM   1232 C CB  . VAL A 1 170 ? 143.683 151.131 118.226 1.00 31.20  ? 244 VAL A CB  1 
ATOM   1233 C CG1 . VAL A 1 170 ? 142.507 151.651 117.416 1.00 41.63  ? 244 VAL A CG1 1 
ATOM   1234 C CG2 . VAL A 1 170 ? 143.211 150.165 119.299 1.00 36.06  ? 244 VAL A CG2 1 
ATOM   1235 N N   . VAL A 1 171 ? 145.071 151.184 115.023 1.00 44.53  ? 245 VAL A N   1 
ATOM   1236 C CA  . VAL A 1 171 ? 145.574 152.036 113.953 1.00 38.51  ? 245 VAL A CA  1 
ATOM   1237 C C   . VAL A 1 171 ? 144.393 152.788 113.360 1.00 44.15  ? 245 VAL A C   1 
ATOM   1238 O O   . VAL A 1 171 ? 143.430 152.172 112.882 1.00 48.89  ? 245 VAL A O   1 
ATOM   1239 C CB  . VAL A 1 171 ? 146.314 151.226 112.879 1.00 42.30  ? 245 VAL A CB  1 
ATOM   1240 C CG1 . VAL A 1 171 ? 146.779 152.139 111.756 1.00 45.78  ? 245 VAL A CG1 1 
ATOM   1241 C CG2 . VAL A 1 171 ? 147.492 150.487 113.492 1.00 42.66  ? 245 VAL A CG2 1 
ATOM   1242 N N   . LYS A 1 172 ? 144.468 154.115 113.392 1.00 49.61  ? 246 LYS A N   1 
ATOM   1243 C CA  . LYS A 1 172 ? 143.406 154.986 112.914 1.00 49.20  ? 246 LYS A CA  1 
ATOM   1244 C C   . LYS A 1 172 ? 143.879 155.760 111.691 1.00 52.71  ? 246 LYS A C   1 
ATOM   1245 O O   . LYS A 1 172 ? 145.027 156.214 111.637 1.00 52.43  ? 246 LYS A O   1 
ATOM   1246 C CB  . LYS A 1 172 ? 142.961 155.960 114.008 1.00 47.44  ? 246 LYS A CB  1 
ATOM   1247 C CG  . LYS A 1 172 ? 142.277 155.294 115.192 1.00 48.13  ? 246 LYS A CG  1 
ATOM   1248 C CD  . LYS A 1 172 ? 141.802 156.317 116.208 1.00 50.37  ? 246 LYS A CD  1 
ATOM   1249 C CE  . LYS A 1 172 ? 141.186 155.642 117.422 1.00 53.19  ? 246 LYS A CE  1 
ATOM   1250 N NZ  . LYS A 1 172 ? 139.909 154.954 117.086 1.00 51.58  ? 246 LYS A NZ  1 
ATOM   1251 N N   . ALA A 1 203 ? 148.268 155.055 116.541 1.00 54.40  ? 277 ALA A N   1 
ATOM   1252 C CA  . ALA A 1 203 ? 149.366 154.235 117.038 1.00 56.44  ? 277 ALA A CA  1 
ATOM   1253 C C   . ALA A 1 203 ? 149.299 154.093 118.555 1.00 56.00  ? 277 ALA A C   1 
ATOM   1254 O O   . ALA A 1 203 ? 150.261 154.395 119.259 1.00 58.20  ? 277 ALA A O   1 
ATOM   1255 C CB  . ALA A 1 203 ? 150.702 154.828 116.620 1.00 57.53  ? 277 ALA A CB  1 
ATOM   1256 N N   . MET A 1 204 ? 148.156 153.629 119.052 1.00 51.61  ? 278 MET A N   1 
ATOM   1257 C CA  . MET A 1 204 ? 147.941 153.428 120.478 1.00 50.41  ? 278 MET A CA  1 
ATOM   1258 C C   . MET A 1 204 ? 148.140 151.957 120.817 1.00 52.55  ? 278 MET A C   1 
ATOM   1259 O O   . MET A 1 204 ? 147.629 151.080 120.114 1.00 55.48  ? 278 MET A O   1 
ATOM   1260 C CB  . MET A 1 204 ? 146.539 153.881 120.888 1.00 48.90  ? 278 MET A CB  1 
ATOM   1261 C CG  . MET A 1 204 ? 146.284 155.376 120.737 1.00 54.75  ? 278 MET A CG  1 
ATOM   1262 S SD  . MET A 1 204 ? 147.359 156.409 121.755 1.00 70.10  ? 278 MET A SD  1 
ATOM   1263 C CE  . MET A 1 204 ? 148.546 156.983 120.542 1.00 56.03  ? 278 MET A CE  1 
ATOM   1264 N N   . GLN A 1 205 ? 148.878 151.692 121.892 1.00 47.56  ? 279 GLN A N   1 
ATOM   1265 C CA  . GLN A 1 205 ? 149.192 150.336 122.318 1.00 43.15  ? 279 GLN A CA  1 
ATOM   1266 C C   . GLN A 1 205 ? 148.628 150.081 123.708 1.00 44.54  ? 279 GLN A C   1 
ATOM   1267 O O   . GLN A 1 205 ? 148.701 150.945 124.588 1.00 50.79  ? 279 GLN A O   1 
ATOM   1268 C CB  . GLN A 1 205 ? 150.704 150.090 122.322 1.00 43.69  ? 279 GLN A CB  1 
ATOM   1269 C CG  . GLN A 1 205 ? 151.342 150.112 120.944 1.00 47.96  ? 279 GLN A CG  1 
ATOM   1270 C CD  . GLN A 1 205 ? 152.839 149.885 120.992 1.00 56.49  ? 279 GLN A CD  1 
ATOM   1271 O OE1 . GLN A 1 205 ? 153.427 149.772 122.068 1.00 54.68  ? 279 GLN A OE1 1 
ATOM   1272 N NE2 . GLN A 1 205 ? 153.467 149.819 119.824 1.00 55.69  ? 279 GLN A NE2 1 
ATOM   1273 N N   . TYR A 1 206 ? 148.065 148.890 123.897 1.00 37.17  ? 280 TYR A N   1 
ATOM   1274 C CA  . TYR A 1 206 ? 147.524 148.473 125.180 1.00 30.59  ? 280 TYR A CA  1 
ATOM   1275 C C   . TYR A 1 206 ? 147.929 147.032 125.453 1.00 36.11  ? 280 TYR A C   1 
ATOM   1276 O O   . TYR A 1 206 ? 148.145 146.243 124.528 1.00 44.17  ? 280 TYR A O   1 
ATOM   1277 C CB  . TYR A 1 206 ? 145.994 148.584 125.225 1.00 34.73  ? 280 TYR A CB  1 
ATOM   1278 C CG  . TYR A 1 206 ? 145.444 149.947 124.871 1.00 39.42  ? 280 TYR A CG  1 
ATOM   1279 C CD1 . TYR A 1 206 ? 145.338 150.945 125.829 1.00 40.61  ? 280 TYR A CD1 1 
ATOM   1280 C CD2 . TYR A 1 206 ? 145.018 150.229 123.580 1.00 38.89  ? 280 TYR A CD2 1 
ATOM   1281 C CE1 . TYR A 1 206 ? 144.830 152.190 125.509 1.00 41.20  ? 280 TYR A CE1 1 
ATOM   1282 C CE2 . TYR A 1 206 ? 144.510 151.470 123.251 1.00 35.96  ? 280 TYR A CE2 1 
ATOM   1283 C CZ  . TYR A 1 206 ? 144.418 152.446 124.218 1.00 37.21  ? 280 TYR A CZ  1 
ATOM   1284 O OH  . TYR A 1 206 ? 143.912 153.683 123.892 1.00 45.85  ? 280 TYR A OH  1 
ATOM   1285 N N   . GLN A 1 207 ? 148.038 146.700 126.736 1.00 32.47  ? 281 GLN A N   1 
ATOM   1286 C CA  . GLN A 1 207 ? 148.202 145.326 127.191 1.00 29.26  ? 281 GLN A CA  1 
ATOM   1287 C C   . GLN A 1 207 ? 146.973 144.958 128.007 1.00 31.08  ? 281 GLN A C   1 
ATOM   1288 O O   . GLN A 1 207 ? 146.672 145.616 129.008 1.00 42.29  ? 281 GLN A O   1 
ATOM   1289 C CB  . GLN A 1 207 ? 149.475 145.161 128.023 1.00 31.36  ? 281 GLN A CB  1 
ATOM   1290 C CG  . GLN A 1 207 ? 150.648 146.000 127.549 1.00 35.73  ? 281 GLN A CG  1 
ATOM   1291 C CD  . GLN A 1 207 ? 151.471 145.300 126.487 1.00 36.37  ? 281 GLN A CD  1 
ATOM   1292 O OE1 . GLN A 1 207 ? 151.606 144.077 126.498 1.00 40.06  ? 281 GLN A OE1 1 
ATOM   1293 N NE2 . GLN A 1 207 ? 152.026 146.073 125.562 1.00 39.50  ? 281 GLN A NE2 1 
ATOM   1294 N N   . VAL A 1 208 ? 146.269 143.914 127.583 1.00 25.52  ? 282 VAL A N   1 
ATOM   1295 C CA  . VAL A 1 208 ? 145.027 143.495 128.222 1.00 20.97  ? 282 VAL A CA  1 
ATOM   1296 C C   . VAL A 1 208 ? 145.235 142.134 128.867 1.00 22.98  ? 282 VAL A C   1 
ATOM   1297 O O   . VAL A 1 208 ? 145.989 141.297 128.356 1.00 30.26  ? 282 VAL A O   1 
ATOM   1298 C CB  . VAL A 1 208 ? 143.854 143.458 127.223 1.00 27.87  ? 282 VAL A CB  1 
ATOM   1299 C CG1 . VAL A 1 208 ? 143.425 144.867 126.870 1.00 32.81  ? 282 VAL A CG1 1 
ATOM   1300 C CG2 . VAL A 1 208 ? 144.240 142.698 125.976 1.00 35.34  ? 282 VAL A CG2 1 
ATOM   1301 N N   . LEU A 1 209 ? 144.558 141.918 129.995 1.00 29.50  ? 283 LEU A N   1 
ATOM   1302 C CA  . LEU A 1 209 ? 144.694 140.686 130.766 1.00 30.68  ? 283 LEU A CA  1 
ATOM   1303 C C   . LEU A 1 209 ? 143.586 139.688 130.442 1.00 36.00  ? 283 LEU A C   1 
ATOM   1304 O O   . LEU A 1 209 ? 143.864 138.555 130.037 1.00 44.77  ? 283 LEU A O   1 
ATOM   1305 C CB  . LEU A 1 209 ? 144.702 141.006 132.264 1.00 38.52  ? 283 LEU A CB  1 
ATOM   1306 C CG  . LEU A 1 209 ? 144.962 139.831 133.208 1.00 35.09  ? 283 LEU A CG  1 
ATOM   1307 C CD1 . LEU A 1 209 ? 146.249 139.109 132.837 1.00 37.34  ? 283 LEU A CD1 1 
ATOM   1308 C CD2 . LEU A 1 209 ? 144.994 140.298 134.651 1.00 32.84  ? 283 LEU A CD2 1 
ATOM   1309 N N   . ASN A 1 210 ? 142.325 140.088 130.620 1.00 34.08  ? 284 ASN A N   1 
ATOM   1310 C CA  . ASN A 1 210 ? 141.227 139.156 130.389 1.00 31.46  ? 284 ASN A CA  1 
ATOM   1311 C C   . ASN A 1 210 ? 140.874 139.054 128.906 1.00 39.12  ? 284 ASN A C   1 
ATOM   1312 O O   . ASN A 1 210 ? 141.022 137.989 128.298 1.00 41.82  ? 284 ASN A O   1 
ATOM   1313 C CB  . ASN A 1 210 ? 140.002 139.563 131.213 1.00 31.35  ? 284 ASN A CB  1 
ATOM   1314 C CG  . ASN A 1 210 ? 140.141 139.222 132.678 1.00 36.86  ? 284 ASN A CG  1 
ATOM   1315 O OD1 . ASN A 1 210 ? 140.681 138.176 133.036 1.00 41.87  ? 284 ASN A OD1 1 
ATOM   1316 N ND2 . ASN A 1 210 ? 139.620 140.087 133.536 1.00 39.93  ? 284 ASN A ND2 1 
ATOM   1317 N N   . GLU A 1 211 ? 140.413 140.149 128.303 1.00 36.16  ? 285 GLU A N   1 
ATOM   1318 C CA  . GLU A 1 211 ? 140.144 140.149 126.870 1.00 27.88  ? 285 GLU A CA  1 
ATOM   1319 C C   . GLU A 1 211 ? 140.120 141.580 126.358 1.00 29.90  ? 285 GLU A C   1 
ATOM   1320 O O   . GLU A 1 211 ? 140.226 142.544 127.120 1.00 44.02  ? 285 GLU A O   1 
ATOM   1321 C CB  . GLU A 1 211 ? 138.810 139.481 126.509 1.00 38.65  ? 285 GLU A CB  1 
ATOM   1322 C CG  . GLU A 1 211 ? 137.557 140.243 126.933 1.00 41.65  ? 285 GLU A CG  1 
ATOM   1323 C CD  . GLU A 1 211 ? 137.122 139.972 128.352 1.00 41.32  ? 285 GLU A CD  1 
ATOM   1324 O OE1 . GLU A 1 211 ? 137.920 139.428 129.129 1.00 48.75  ? 285 GLU A OE1 1 
ATOM   1325 O OE2 . GLU A 1 211 ? 135.970 140.311 128.693 1.00 44.13  ? 285 GLU A OE2 1 
ATOM   1326 N N   . VAL A 1 212 ? 139.976 141.695 125.041 1.00 27.62  ? 286 VAL A N   1 
ATOM   1327 C CA  . VAL A 1 212 ? 139.575 142.927 124.375 1.00 30.61  ? 286 VAL A CA  1 
ATOM   1328 C C   . VAL A 1 212 ? 138.306 142.625 123.586 1.00 31.90  ? 286 VAL A C   1 
ATOM   1329 O O   . VAL A 1 212 ? 138.238 141.619 122.870 1.00 32.72  ? 286 VAL A O   1 
ATOM   1330 C CB  . VAL A 1 212 ? 140.694 143.486 123.474 1.00 24.27  ? 286 VAL A CB  1 
ATOM   1331 C CG1 . VAL A 1 212 ? 141.090 142.491 122.397 1.00 26.57  ? 286 VAL A CG1 1 
ATOM   1332 C CG2 . VAL A 1 212 ? 140.260 144.795 122.846 1.00 38.33  ? 286 VAL A CG2 1 
ATOM   1333 N N   . VAL A 1 213 ? 137.291 143.468 123.750 1.00 30.33  ? 287 VAL A N   1 
ATOM   1334 C CA  . VAL A 1 213 ? 135.961 143.210 123.206 1.00 27.47  ? 287 VAL A CA  1 
ATOM   1335 C C   . VAL A 1 213 ? 135.672 144.236 122.121 1.00 33.32  ? 287 VAL A C   1 
ATOM   1336 O O   . VAL A 1 213 ? 135.701 145.445 122.374 1.00 42.47  ? 287 VAL A O   1 
ATOM   1337 C CB  . VAL A 1 213 ? 134.883 143.251 124.300 1.00 31.50  ? 287 VAL A CB  1 
ATOM   1338 C CG1 . VAL A 1 213 ? 133.500 143.351 123.679 1.00 35.67  ? 287 VAL A CG1 1 
ATOM   1339 C CG2 . VAL A 1 213 ? 134.977 142.022 125.183 1.00 35.27  ? 287 VAL A CG2 1 
ATOM   1340 N N   . ILE A 1 214 ? 135.383 143.753 120.918 1.00 36.02  ? 288 ILE A N   1 
ATOM   1341 C CA  . ILE A 1 214 ? 134.942 144.588 119.808 1.00 32.31  ? 288 ILE A CA  1 
ATOM   1342 C C   . ILE A 1 214 ? 133.466 144.290 119.596 1.00 29.60  ? 288 ILE A C   1 
ATOM   1343 O O   . ILE A 1 214 ? 133.106 143.198 119.143 1.00 39.09  ? 288 ILE A O   1 
ATOM   1344 C CB  . ILE A 1 214 ? 135.754 144.328 118.534 1.00 27.89  ? 288 ILE A CB  1 
ATOM   1345 C CG1 . ILE A 1 214 ? 137.246 144.513 118.809 1.00 40.10  ? 288 ILE A CG1 1 
ATOM   1346 C CG2 . ILE A 1 214 ? 135.295 145.246 117.413 1.00 35.49  ? 288 ILE A CG2 1 
ATOM   1347 C CD1 . ILE A 1 214 ? 137.989 143.217 119.039 1.00 37.67  ? 288 ILE A CD1 1 
ATOM   1348 N N   . ASP A 1 215 ? 132.611 145.258 119.913 1.00 40.85  ? 289 ASP A N   1 
ATOM   1349 C CA  . ASP A 1 215 ? 131.174 145.034 119.958 1.00 40.07  ? 289 ASP A CA  1 
ATOM   1350 C C   . ASP A 1 215 ? 130.449 146.253 119.393 1.00 45.14  ? 289 ASP A C   1 
ATOM   1351 O O   . ASP A 1 215 ? 131.047 147.121 118.750 1.00 52.85  ? 289 ASP A O   1 
ATOM   1352 C CB  . ASP A 1 215 ? 130.745 144.663 121.389 1.00 43.41  ? 289 ASP A CB  1 
ATOM   1353 C CG  . ASP A 1 215 ? 130.784 145.841 122.372 1.00 51.39  ? 289 ASP A CG  1 
ATOM   1354 O OD1 . ASP A 1 215 ? 130.784 147.023 121.969 1.00 52.24  ? 289 ASP A OD1 1 
ATOM   1355 O OD2 . ASP A 1 215 ? 130.826 145.568 123.589 1.00 51.99  ? 289 ASP A OD2 1 
ATOM   1356 N N   . ARG A 1 216 ? 129.141 146.294 119.628 1.00 49.41  ? 290 ARG A N   1 
ATOM   1357 C CA  . ARG A 1 216 ? 128.285 147.411 119.259 1.00 48.31  ? 290 ARG A CA  1 
ATOM   1358 C C   . ARG A 1 216 ? 127.603 147.951 120.508 1.00 49.16  ? 290 ARG A C   1 
ATOM   1359 O O   . ARG A 1 216 ? 127.163 147.182 121.369 1.00 54.92  ? 290 ARG A O   1 
ATOM   1360 C CB  . ARG A 1 216 ? 127.264 146.984 118.185 1.00 49.07  ? 290 ARG A CB  1 
ATOM   1361 C CG  . ARG A 1 216 ? 126.323 145.833 118.558 1.00 51.25  ? 290 ARG A CG  1 
ATOM   1362 C CD  . ARG A 1 216 ? 125.052 146.281 119.260 1.00 53.88  ? 290 ARG A CD  1 
ATOM   1363 N NE  . ARG A 1 216 ? 124.129 145.170 119.454 1.00 52.45  ? 290 ARG A NE  1 
ATOM   1364 C CZ  . ARG A 1 216 ? 123.001 145.243 120.147 1.00 53.53  ? 290 ARG A CZ  1 
ATOM   1365 N NH1 . ARG A 1 216 ? 122.620 146.368 120.730 1.00 53.71  ? 290 ARG A NH1 1 
ATOM   1366 N NH2 . ARG A 1 216 ? 122.236 144.161 120.259 1.00 51.11  ? 290 ARG A NH2 1 
ATOM   1367 N N   . GLY A 1 217 ? 127.539 149.274 120.614 1.00 54.75  ? 291 GLY A N   1 
ATOM   1368 C CA  . GLY A 1 217 ? 127.043 149.917 121.808 1.00 57.67  ? 291 GLY A CA  1 
ATOM   1369 C C   . GLY A 1 217 ? 125.628 150.432 121.659 1.00 58.57  ? 291 GLY A C   1 
ATOM   1370 O O   . GLY A 1 217 ? 124.653 149.679 121.753 1.00 60.86  ? 291 GLY A O   1 
ATOM   1371 N N   . PRO A 1 218 ? 125.489 151.740 121.432 1.00 55.83  ? 292 PRO A N   1 
ATOM   1372 C CA  . PRO A 1 218 ? 124.145 152.323 121.291 1.00 59.14  ? 292 PRO A CA  1 
ATOM   1373 C C   . PRO A 1 218 ? 123.366 151.783 120.107 1.00 58.58  ? 292 PRO A C   1 
ATOM   1374 O O   . PRO A 1 218 ? 122.135 151.907 120.088 1.00 60.39  ? 292 PRO A O   1 
ATOM   1375 C CB  . PRO A 1 218 ? 124.432 153.824 121.139 1.00 62.19  ? 292 PRO A CB  1 
ATOM   1376 C CG  . PRO A 1 218 ? 125.827 153.878 120.597 1.00 60.06  ? 292 PRO A CG  1 
ATOM   1377 C CD  . PRO A 1 218 ? 126.546 152.753 121.278 1.00 57.75  ? 292 PRO A CD  1 
ATOM   1378 N N   . SER A 1 219 ? 124.037 151.196 119.119 1.00 56.89  ? 293 SER A N   1 
ATOM   1379 C CA  . SER A 1 219 ? 123.341 150.623 117.976 1.00 54.61  ? 293 SER A CA  1 
ATOM   1380 C C   . SER A 1 219 ? 122.477 149.447 118.411 1.00 57.45  ? 293 SER A C   1 
ATOM   1381 O O   . SER A 1 219 ? 122.881 148.630 119.243 1.00 59.99  ? 293 SER A O   1 
ATOM   1382 C CB  . SER A 1 219 ? 124.343 150.174 116.914 1.00 56.03  ? 293 SER A CB  1 
ATOM   1383 O OG  . SER A 1 219 ? 123.707 149.416 115.900 1.00 58.48  ? 293 SER A OG  1 
ATOM   1384 N N   . SER A 1 220 ? 121.274 149.369 117.848 1.00 66.77  ? 294 SER A N   1 
ATOM   1385 C CA  . SER A 1 220 ? 120.352 148.275 118.113 1.00 68.70  ? 294 SER A CA  1 
ATOM   1386 C C   . SER A 1 220 ? 120.348 147.233 117.003 1.00 66.64  ? 294 SER A C   1 
ATOM   1387 O O   . SER A 1 220 ? 119.538 146.301 117.043 1.00 68.36  ? 294 SER A O   1 
ATOM   1388 C CB  . SER A 1 220 ? 118.937 148.817 118.327 1.00 68.57  ? 294 SER A CB  1 
ATOM   1389 O OG  . SER A 1 220 ? 118.874 149.642 119.477 1.00 67.31  ? 294 SER A OG  1 
ATOM   1390 N N   . TYR A 1 221 ? 121.231 147.367 116.020 1.00 66.33  ? 295 TYR A N   1 
ATOM   1391 C CA  . TYR A 1 221 ? 121.301 146.468 114.880 1.00 68.74  ? 295 TYR A CA  1 
ATOM   1392 C C   . TYR A 1 221 ? 122.507 145.543 115.015 1.00 67.86  ? 295 TYR A C   1 
ATOM   1393 O O   . TYR A 1 221 ? 123.329 145.675 115.926 1.00 64.53  ? 295 TYR A O   1 
ATOM   1394 C CB  . TYR A 1 221 ? 121.364 147.263 113.574 1.00 68.97  ? 295 TYR A CB  1 
ATOM   1395 C CG  . TYR A 1 221 ? 120.316 148.348 113.466 1.00 72.17  ? 295 TYR A CG  1 
ATOM   1396 C CD1 . TYR A 1 221 ? 118.968 148.031 113.368 1.00 70.77  ? 295 TYR A CD1 1 
ATOM   1397 C CD2 . TYR A 1 221 ? 120.676 149.689 113.462 1.00 71.44  ? 295 TYR A CD2 1 
ATOM   1398 C CE1 . TYR A 1 221 ? 118.007 149.019 113.269 1.00 70.11  ? 295 TYR A CE1 1 
ATOM   1399 C CE2 . TYR A 1 221 ? 119.723 150.684 113.364 1.00 71.95  ? 295 TYR A CE2 1 
ATOM   1400 C CZ  . TYR A 1 221 ? 118.390 150.344 113.267 1.00 73.31  ? 295 TYR A CZ  1 
ATOM   1401 O OH  . TYR A 1 221 ? 117.438 151.332 113.169 1.00 70.53  ? 295 TYR A OH  1 
ATOM   1402 N N   . LEU A 1 222 ? 122.600 144.593 114.090 1.00 56.45  ? 296 LEU A N   1 
ATOM   1403 C CA  . LEU A 1 222 ? 123.719 143.665 114.067 1.00 53.18  ? 296 LEU A CA  1 
ATOM   1404 C C   . LEU A 1 222 ? 125.018 144.386 113.725 1.00 52.33  ? 296 LEU A C   1 
ATOM   1405 O O   . LEU A 1 222 ? 125.027 145.406 113.031 1.00 57.90  ? 296 LEU A O   1 
ATOM   1406 C CB  . LEU A 1 222 ? 123.459 142.547 113.059 1.00 53.21  ? 296 LEU A CB  1 
ATOM   1407 C CG  . LEU A 1 222 ? 122.341 141.582 113.446 1.00 50.96  ? 296 LEU A CG  1 
ATOM   1408 C CD1 . LEU A 1 222 ? 122.018 140.630 112.314 1.00 54.03  ? 296 LEU A CD1 1 
ATOM   1409 C CD2 . LEU A 1 222 ? 122.778 140.810 114.668 1.00 51.78  ? 296 LEU A CD2 1 
ATOM   1410 N N   . SER A 1 223 ? 126.122 143.842 114.225 1.00 48.65  ? 297 SER A N   1 
ATOM   1411 C CA  . SER A 1 223 ? 127.455 144.358 113.949 1.00 49.19  ? 297 SER A CA  1 
ATOM   1412 C C   . SER A 1 223 ? 128.203 143.359 113.080 1.00 54.20  ? 297 SER A C   1 
ATOM   1413 O O   . SER A 1 223 ? 128.265 142.170 113.410 1.00 52.92  ? 297 SER A O   1 
ATOM   1414 C CB  . SER A 1 223 ? 128.226 144.617 115.245 1.00 50.21  ? 297 SER A CB  1 
ATOM   1415 O OG  . SER A 1 223 ? 128.628 143.401 115.852 1.00 52.63  ? 297 SER A OG  1 
ATOM   1416 N N   . ASN A 1 224 ? 128.754 143.843 111.969 1.00 57.50  ? 298 ASN A N   1 
ATOM   1417 C CA  . ASN A 1 224 ? 129.523 143.036 111.027 1.00 50.81  ? 298 ASN A CA  1 
ATOM   1418 C C   . ASN A 1 224 ? 130.986 143.436 111.146 1.00 49.59  ? 298 ASN A C   1 
ATOM   1419 O O   . ASN A 1 224 ? 131.353 144.560 110.789 1.00 49.76  ? 298 ASN A O   1 
ATOM   1420 C CB  . ASN A 1 224 ? 129.032 143.246 109.596 1.00 49.28  ? 298 ASN A CB  1 
ATOM   1421 C CG  . ASN A 1 224 ? 127.671 142.645 109.351 1.00 56.67  ? 298 ASN A CG  1 
ATOM   1422 O OD1 . ASN A 1 224 ? 127.387 141.537 109.794 1.00 56.31  ? 298 ASN A OD1 1 
ATOM   1423 N ND2 . ASN A 1 224 ? 126.819 143.373 108.640 1.00 56.37  ? 298 ASN A ND2 1 
ATOM   1424 N N   . VAL A 1 225 ? 131.826 142.527 111.641 1.00 44.42  ? 299 VAL A N   1 
ATOM   1425 C CA  . VAL A 1 225 ? 133.259 142.806 111.663 1.00 38.71  ? 299 VAL A CA  1 
ATOM   1426 C C   . VAL A 1 225 ? 134.028 141.619 111.100 1.00 40.67  ? 299 VAL A C   1 
ATOM   1427 O O   . VAL A 1 225 ? 133.629 140.459 111.247 1.00 46.24  ? 299 VAL A O   1 
ATOM   1428 C CB  . VAL A 1 225 ? 133.789 143.186 113.071 1.00 41.40  ? 299 VAL A CB  1 
ATOM   1429 C CG1 . VAL A 1 225 ? 133.092 144.432 113.598 1.00 43.15  ? 299 VAL A CG1 1 
ATOM   1430 C CG2 . VAL A 1 225 ? 133.656 142.051 114.043 1.00 42.61  ? 299 VAL A CG2 1 
ATOM   1431 N N   . ASP A 1 226 ? 135.150 141.929 110.453 1.00 46.22  ? 300 ASP A N   1 
ATOM   1432 C CA  . ASP A 1 226 ? 135.982 140.956 109.761 1.00 39.73  ? 300 ASP A CA  1 
ATOM   1433 C C   . ASP A 1 226 ? 137.230 140.665 110.582 1.00 38.56  ? 300 ASP A C   1 
ATOM   1434 O O   . ASP A 1 226 ? 137.839 141.581 111.148 1.00 44.72  ? 300 ASP A O   1 
ATOM   1435 C CB  . ASP A 1 226 ? 136.391 141.478 108.382 1.00 45.27  ? 300 ASP A CB  1 
ATOM   1436 C CG  . ASP A 1 226 ? 135.382 141.144 107.306 1.00 54.00  ? 300 ASP A CG  1 
ATOM   1437 O OD1 . ASP A 1 226 ? 134.210 140.896 107.650 1.00 52.47  ? 300 ASP A OD1 1 
ATOM   1438 O OD2 . ASP A 1 226 ? 135.760 141.130 106.116 1.00 56.97  ? 300 ASP A OD2 1 
ATOM   1439 N N   . VAL A 1 227 ? 137.619 139.390 110.628 1.00 32.83  ? 301 VAL A N   1 
ATOM   1440 C CA  . VAL A 1 227 ? 138.777 138.938 111.391 1.00 30.84  ? 301 VAL A CA  1 
ATOM   1441 C C   . VAL A 1 227 ? 139.778 138.308 110.432 1.00 32.43  ? 301 VAL A C   1 
ATOM   1442 O O   . VAL A 1 227 ? 139.412 137.448 109.622 1.00 39.76  ? 301 VAL A O   1 
ATOM   1443 C CB  . VAL A 1 227 ? 138.373 137.938 112.490 1.00 30.07  ? 301 VAL A CB  1 
ATOM   1444 C CG1 . VAL A 1 227 ? 139.602 137.415 113.215 1.00 34.32  ? 301 VAL A CG1 1 
ATOM   1445 C CG2 . VAL A 1 227 ? 137.403 138.583 113.466 1.00 35.41  ? 301 VAL A CG2 1 
ATOM   1446 N N   . TYR A 1 228 ? 141.035 138.735 110.525 1.00 32.42  ? 302 TYR A N   1 
ATOM   1447 C CA  . TYR A 1 228 ? 142.140 138.170 109.765 1.00 28.33  ? 302 TYR A CA  1 
ATOM   1448 C C   . TYR A 1 228 ? 143.082 137.457 110.722 1.00 35.59  ? 302 TYR A C   1 
ATOM   1449 O O   . TYR A 1 228 ? 143.449 138.013 111.763 1.00 42.43  ? 302 TYR A O   1 
ATOM   1450 C CB  . TYR A 1 228 ? 142.923 139.251 109.014 1.00 30.76  ? 302 TYR A CB  1 
ATOM   1451 C CG  . TYR A 1 228 ? 142.191 139.953 107.894 1.00 28.13  ? 302 TYR A CG  1 
ATOM   1452 C CD1 . TYR A 1 228 ? 140.980 139.481 107.416 1.00 39.81  ? 302 TYR A CD1 1 
ATOM   1453 C CD2 . TYR A 1 228 ? 142.736 141.080 107.294 1.00 36.59  ? 302 TYR A CD2 1 
ATOM   1454 C CE1 . TYR A 1 228 ? 140.323 140.126 106.386 1.00 39.30  ? 302 TYR A CE1 1 
ATOM   1455 C CE2 . TYR A 1 228 ? 142.089 141.725 106.263 1.00 38.48  ? 302 TYR A CE2 1 
ATOM   1456 C CZ  . TYR A 1 228 ? 140.882 141.245 105.814 1.00 35.16  ? 302 TYR A CZ  1 
ATOM   1457 O OH  . TYR A 1 228 ? 140.229 141.887 104.787 1.00 42.05  ? 302 TYR A OH  1 
ATOM   1458 N N   . LEU A 1 229 ? 143.482 136.240 110.363 1.00 31.96  ? 303 LEU A N   1 
ATOM   1459 C CA  . LEU A 1 229 ? 144.508 135.498 111.089 1.00 21.24  ? 303 LEU A CA  1 
ATOM   1460 C C   . LEU A 1 229 ? 145.687 135.311 110.144 1.00 28.49  ? 303 LEU A C   1 
ATOM   1461 O O   . LEU A 1 229 ? 145.571 134.609 109.134 1.00 42.29  ? 303 LEU A O   1 
ATOM   1462 C CB  . LEU A 1 229 ? 143.971 134.158 111.594 1.00 32.34  ? 303 LEU A CB  1 
ATOM   1463 C CG  . LEU A 1 229 ? 144.818 133.340 112.575 1.00 35.13  ? 303 LEU A CG  1 
ATOM   1464 C CD1 . LEU A 1 229 ? 143.917 132.479 113.441 1.00 35.66  ? 303 LEU A CD1 1 
ATOM   1465 C CD2 . LEU A 1 229 ? 145.836 132.468 111.854 1.00 39.18  ? 303 LEU A CD2 1 
ATOM   1466 N N   . ASP A 1 230 ? 146.815 135.941 110.475 1.00 32.85  ? 304 ASP A N   1 
ATOM   1467 C CA  . ASP A 1 230 ? 148.018 135.915 109.641 1.00 30.40  ? 304 ASP A CA  1 
ATOM   1468 C C   . ASP A 1 230 ? 147.731 136.432 108.232 1.00 34.38  ? 304 ASP A C   1 
ATOM   1469 O O   . ASP A 1 230 ? 148.231 135.898 107.240 1.00 43.60  ? 304 ASP A O   1 
ATOM   1470 C CB  . ASP A 1 230 ? 148.630 134.513 109.593 1.00 37.67  ? 304 ASP A CB  1 
ATOM   1471 C CG  . ASP A 1 230 ? 149.443 134.190 110.831 1.00 41.61  ? 304 ASP A CG  1 
ATOM   1472 O OD1 . ASP A 1 230 ? 149.503 135.040 111.744 1.00 39.29  ? 304 ASP A OD1 1 
ATOM   1473 O OD2 . ASP A 1 230 ? 150.022 133.085 110.893 1.00 41.72  ? 304 ASP A OD2 1 
ATOM   1474 N N   . GLY A 1 231 ? 146.920 137.483 108.144 1.00 32.48  ? 305 GLY A N   1 
ATOM   1475 C CA  . GLY A 1 231 ? 146.633 138.120 106.875 1.00 28.01  ? 305 GLY A CA  1 
ATOM   1476 C C   . GLY A 1 231 ? 145.589 137.439 106.022 1.00 27.41  ? 305 GLY A C   1 
ATOM   1477 O O   . GLY A 1 231 ? 145.423 137.820 104.858 1.00 38.76  ? 305 GLY A O   1 
ATOM   1478 N N   . HIS A 1 232 ? 144.878 136.450 106.554 1.00 31.03  ? 306 HIS A N   1 
ATOM   1479 C CA  . HIS A 1 232 ? 143.884 135.698 105.802 1.00 30.26  ? 306 HIS A CA  1 
ATOM   1480 C C   . HIS A 1 232 ? 142.517 135.887 106.442 1.00 32.63  ? 306 HIS A C   1 
ATOM   1481 O O   . HIS A 1 232 ? 142.375 135.742 107.660 1.00 41.37  ? 306 HIS A O   1 
ATOM   1482 C CB  . HIS A 1 232 ? 144.241 134.210 105.758 1.00 35.89  ? 306 HIS A CB  1 
ATOM   1483 C CG  . HIS A 1 232 ? 145.413 133.894 104.883 1.00 38.63  ? 306 HIS A CG  1 
ATOM   1484 N ND1 . HIS A 1 232 ? 145.933 134.795 103.980 1.00 44.00  ? 306 HIS A ND1 1 
ATOM   1485 C CD2 . HIS A 1 232 ? 146.172 132.777 104.778 1.00 36.99  ? 306 HIS A CD2 1 
ATOM   1486 C CE1 . HIS A 1 232 ? 146.959 134.247 103.354 1.00 40.15  ? 306 HIS A CE1 1 
ATOM   1487 N NE2 . HIS A 1 232 ? 147.124 133.022 103.820 1.00 39.99  ? 306 HIS A NE2 1 
ATOM   1488 N N   . LEU A 1 233 ? 141.517 136.203 105.623 1.00 28.07  ? 307 LEU A N   1 
ATOM   1489 C CA  . LEU A 1 233 ? 140.144 136.316 106.106 1.00 21.66  ? 307 LEU A CA  1 
ATOM   1490 C C   . LEU A 1 233 ? 139.661 134.950 106.573 1.00 25.58  ? 307 LEU A C   1 
ATOM   1491 O O   . LEU A 1 233 ? 139.427 134.052 105.758 1.00 41.57  ? 307 LEU A O   1 
ATOM   1492 C CB  . LEU A 1 233 ? 139.238 136.869 105.011 1.00 30.20  ? 307 LEU A CB  1 
ATOM   1493 C CG  . LEU A 1 233 ? 137.765 137.085 105.372 1.00 30.76  ? 307 LEU A CG  1 
ATOM   1494 C CD1 . LEU A 1 233 ? 137.593 138.107 106.480 1.00 29.22  ? 307 LEU A CD1 1 
ATOM   1495 C CD2 . LEU A 1 233 ? 136.973 137.497 104.140 1.00 35.72  ? 307 LEU A CD2 1 
ATOM   1496 N N   . ILE A 1 234 ? 139.511 134.790 107.886 1.00 26.26  ? 308 ILE A N   1 
ATOM   1497 C CA  . ILE A 1 234 ? 139.075 133.519 108.448 1.00 31.01  ? 308 ILE A CA  1 
ATOM   1498 C C   . ILE A 1 234 ? 137.580 133.562 108.723 1.00 33.07  ? 308 ILE A C   1 
ATOM   1499 O O   . ILE A 1 234 ? 136.896 132.537 108.628 1.00 40.58  ? 308 ILE A O   1 
ATOM   1500 C CB  . ILE A 1 234 ? 139.866 133.165 109.721 1.00 31.14  ? 308 ILE A CB  1 
ATOM   1501 C CG1 . ILE A 1 234 ? 139.656 134.224 110.806 1.00 36.34  ? 308 ILE A CG1 1 
ATOM   1502 C CG2 . ILE A 1 234 ? 141.341 132.998 109.398 1.00 37.08  ? 308 ILE A CG2 1 
ATOM   1503 C CD1 . ILE A 1 234 ? 140.193 133.824 112.160 1.00 36.92  ? 308 ILE A CD1 1 
ATOM   1504 N N   . THR A 1 235 ? 137.056 134.742 109.051 1.00 33.73  ? 309 THR A N   1 
ATOM   1505 C CA  . THR A 1 235 ? 135.643 134.838 109.382 1.00 34.74  ? 309 THR A CA  1 
ATOM   1506 C C   . THR A 1 235 ? 135.176 136.286 109.340 1.00 31.92  ? 309 THR A C   1 
ATOM   1507 O O   . THR A 1 235 ? 135.965 137.226 109.495 1.00 41.73  ? 309 THR A O   1 
ATOM   1508 C CB  . THR A 1 235 ? 135.346 134.239 110.763 1.00 41.84  ? 309 THR A CB  1 
ATOM   1509 O OG1 . THR A 1 235 ? 133.929 134.195 110.973 1.00 42.54  ? 309 THR A OG1 1 
ATOM   1510 C CG2 . THR A 1 235 ? 135.993 135.068 111.863 1.00 41.56  ? 309 THR A CG2 1 
ATOM   1511 N N   . THR A 1 236 ? 133.879 136.439 109.097 1.00 34.39  ? 310 THR A N   1 
ATOM   1512 C CA  . THR A 1 236 ? 133.144 137.668 109.345 1.00 38.89  ? 310 THR A CA  1 
ATOM   1513 C C   . THR A 1 236 ? 132.019 137.337 110.313 1.00 38.84  ? 310 THR A C   1 
ATOM   1514 O O   . THR A 1 236 ? 131.295 136.355 110.117 1.00 42.11  ? 310 THR A O   1 
ATOM   1515 C CB  . THR A 1 236 ? 132.596 138.273 108.044 1.00 42.94  ? 310 THR A CB  1 
ATOM   1516 O OG1 . THR A 1 236 ? 131.826 139.445 108.343 1.00 43.49  ? 310 THR A OG1 1 
ATOM   1517 C CG2 . THR A 1 236 ? 131.741 137.273 107.271 1.00 44.43  ? 310 THR A CG2 1 
ATOM   1518 N N   . VAL A 1 237 ? 131.889 138.126 111.373 1.00 42.64  ? 311 VAL A N   1 
ATOM   1519 C CA  . VAL A 1 237 ? 130.907 137.850 112.412 1.00 39.06  ? 311 VAL A CA  1 
ATOM   1520 C C   . VAL A 1 237 ? 129.830 138.923 112.374 1.00 43.08  ? 311 VAL A C   1 
ATOM   1521 O O   . VAL A 1 237 ? 130.118 140.122 112.230 1.00 48.91  ? 311 VAL A O   1 
ATOM   1522 C CB  . VAL A 1 237 ? 131.543 137.735 113.812 1.00 41.65  ? 311 VAL A CB  1 
ATOM   1523 C CG1 . VAL A 1 237 ? 132.528 136.577 113.847 1.00 44.92  ? 311 VAL A CG1 1 
ATOM   1524 C CG2 . VAL A 1 237 ? 132.221 139.008 114.202 1.00 39.77  ? 311 VAL A CG2 1 
ATOM   1525 N N   . GLN A 1 238 ? 128.583 138.465 112.475 1.00 42.63  ? 312 GLN A N   1 
ATOM   1526 C CA  . GLN A 1 238 ? 127.364 139.261 112.395 1.00 43.74  ? 312 GLN A CA  1 
ATOM   1527 C C   . GLN A 1 238 ? 126.613 139.057 113.706 1.00 46.38  ? 312 GLN A C   1 
ATOM   1528 O O   . GLN A 1 238 ? 125.853 138.098 113.860 1.00 49.04  ? 312 GLN A O   1 
ATOM   1529 C CB  . GLN A 1 238 ? 126.520 138.839 111.192 1.00 47.54  ? 312 GLN A CB  1 
ATOM   1530 C CG  . GLN A 1 238 ? 125.266 139.666 110.969 1.00 52.56  ? 312 GLN A CG  1 
ATOM   1531 C CD  . GLN A 1 238 ? 124.505 139.237 109.729 1.00 54.83  ? 312 GLN A CD  1 
ATOM   1532 O OE1 . GLN A 1 238 ? 124.895 138.290 109.047 1.00 55.34  ? 312 GLN A OE1 1 
ATOM   1533 N NE2 . GLN A 1 238 ? 123.420 139.939 109.427 1.00 53.53  ? 312 GLN A NE2 1 
ATOM   1534 N N   . GLY A 1 239 ? 126.834 139.962 114.651 1.00 48.10  ? 313 GLY A N   1 
ATOM   1535 C CA  . GLY A 1 239 ? 126.180 139.875 115.939 1.00 42.47  ? 313 GLY A CA  1 
ATOM   1536 C C   . GLY A 1 239 ? 126.579 140.994 116.873 1.00 46.49  ? 313 GLY A C   1 
ATOM   1537 O O   . GLY A 1 239 ? 126.862 142.110 116.426 1.00 56.34  ? 313 GLY A O   1 
ATOM   1538 N N   . ASP A 1 240 ? 126.604 140.714 118.176 1.00 36.16  ? 314 ASP A N   1 
ATOM   1539 C CA  . ASP A 1 240 ? 126.986 141.748 119.131 1.00 36.46  ? 314 ASP A CA  1 
ATOM   1540 C C   . ASP A 1 240 ? 128.481 142.036 119.068 1.00 37.57  ? 314 ASP A C   1 
ATOM   1541 O O   . ASP A 1 240 ? 128.886 143.202 119.040 1.00 46.25  ? 314 ASP A O   1 
ATOM   1542 C CB  . ASP A 1 240 ? 126.567 141.344 120.541 1.00 40.61  ? 314 ASP A CB  1 
ATOM   1543 C CG  . ASP A 1 240 ? 125.066 141.182 120.679 1.00 43.81  ? 314 ASP A CG  1 
ATOM   1544 O OD1 . ASP A 1 240 ? 124.383 141.067 119.640 1.00 48.26  ? 314 ASP A OD1 1 
ATOM   1545 O OD2 . ASP A 1 240 ? 124.571 141.164 121.825 1.00 45.18  ? 314 ASP A OD2 1 
ATOM   1546 N N   . GLY A 1 241 ? 129.314 141.001 119.027 1.00 28.36  ? 315 GLY A N   1 
ATOM   1547 C CA  . GLY A 1 241 ? 130.743 141.218 118.929 1.00 29.83  ? 315 GLY A CA  1 
ATOM   1548 C C   . GLY A 1 241 ? 131.527 139.949 119.206 1.00 27.20  ? 315 GLY A C   1 
ATOM   1549 O O   . GLY A 1 241 ? 130.977 138.846 119.230 1.00 38.07  ? 315 GLY A O   1 
ATOM   1550 N N   . VAL A 1 242 ? 132.834 140.137 119.412 1.00 23.96  ? 316 VAL A N   1 
ATOM   1551 C CA  . VAL A 1 242 ? 133.775 139.052 119.664 1.00 24.79  ? 316 VAL A CA  1 
ATOM   1552 C C   . VAL A 1 242 ? 134.532 139.330 120.957 1.00 30.57  ? 316 VAL A C   1 
ATOM   1553 O O   . VAL A 1 242 ? 134.708 140.483 121.361 1.00 38.99  ? 316 VAL A O   1 
ATOM   1554 C CB  . VAL A 1 242 ? 134.760 138.857 118.490 1.00 22.13  ? 316 VAL A CB  1 
ATOM   1555 C CG1 . VAL A 1 242 ? 134.021 138.393 117.254 1.00 28.13  ? 316 VAL A CG1 1 
ATOM   1556 C CG2 . VAL A 1 242 ? 135.508 140.147 118.205 1.00 29.98  ? 316 VAL A CG2 1 
ATOM   1557 N N   . ILE A 1 243 ? 134.981 138.255 121.608 1.00 28.24  ? 317 ILE A N   1 
ATOM   1558 C CA  . ILE A 1 243 ? 135.547 138.331 122.952 1.00 22.23  ? 317 ILE A CA  1 
ATOM   1559 C C   . ILE A 1 243 ? 136.957 137.742 122.930 1.00 30.41  ? 317 ILE A C   1 
ATOM   1560 O O   . ILE A 1 243 ? 137.334 136.978 123.826 1.00 42.85  ? 317 ILE A O   1 
ATOM   1561 C CB  . ILE A 1 243 ? 134.650 137.611 123.977 1.00 25.53  ? 317 ILE A CB  1 
ATOM   1562 C CG1 . ILE A 1 243 ? 133.268 138.233 124.018 1.00 28.50  ? 317 ILE A CG1 1 
ATOM   1563 C CG2 . ILE A 1 243 ? 135.138 137.844 125.401 1.00 33.82  ? 317 ILE A CG2 1 
ATOM   1564 C CD1 . ILE A 1 243 ? 132.289 137.396 124.808 1.00 35.84  ? 317 ILE A CD1 1 
ATOM   1565 N N   . VAL A 1 244 ? 137.713 137.998 121.860 1.00 21.86  ? 318 VAL A N   1 
ATOM   1566 C CA  . VAL A 1 244 ? 139.079 137.482 121.756 1.00 29.17  ? 318 VAL A CA  1 
ATOM   1567 C C   . VAL A 1 244 ? 139.830 137.725 123.063 1.00 28.39  ? 318 VAL A C   1 
ATOM   1568 O O   . VAL A 1 244 ? 139.914 138.858 123.548 1.00 32.50  ? 318 VAL A O   1 
ATOM   1569 C CB  . VAL A 1 244 ? 139.816 138.098 120.550 1.00 26.05  ? 318 VAL A CB  1 
ATOM   1570 C CG1 . VAL A 1 244 ? 139.774 139.615 120.601 1.00 31.24  ? 318 VAL A CG1 1 
ATOM   1571 C CG2 . VAL A 1 244 ? 141.254 137.616 120.516 1.00 30.03  ? 318 VAL A CG2 1 
ATOM   1572 N N   . SER A 1 245 ? 140.364 136.654 123.652 1.00 28.14  ? 319 SER A N   1 
ATOM   1573 C CA  . SER A 1 245 ? 140.727 136.674 125.062 1.00 17.99  ? 319 SER A CA  1 
ATOM   1574 C C   . SER A 1 245 ? 141.968 135.833 125.323 1.00 28.19  ? 319 SER A C   1 
ATOM   1575 O O   . SER A 1 245 ? 142.340 134.964 124.531 1.00 32.35  ? 319 SER A O   1 
ATOM   1576 C CB  . SER A 1 245 ? 139.578 136.158 125.936 1.00 24.63  ? 319 SER A CB  1 
ATOM   1577 O OG  . SER A 1 245 ? 139.515 134.743 125.913 1.00 32.79  ? 319 SER A OG  1 
ATOM   1578 N N   . THR A 1 246 ? 142.601 136.115 126.457 1.00 31.52  ? 320 THR A N   1 
ATOM   1579 C CA  . THR A 1 246 ? 143.667 135.293 127.006 1.00 24.97  ? 320 THR A CA  1 
ATOM   1580 C C   . THR A 1 246 ? 143.079 134.079 127.712 1.00 29.55  ? 320 THR A C   1 
ATOM   1581 O O   . THR A 1 246 ? 141.877 134.024 127.985 1.00 33.37  ? 320 THR A O   1 
ATOM   1582 C CB  . THR A 1 246 ? 144.505 136.115 127.983 1.00 23.06  ? 320 THR A CB  1 
ATOM   1583 O OG1 . THR A 1 246 ? 143.664 136.604 129.033 1.00 31.03  ? 320 THR A OG1 1 
ATOM   1584 C CG2 . THR A 1 246 ? 145.161 137.283 127.285 1.00 27.88  ? 320 THR A CG2 1 
ATOM   1585 N N   . PRO A 1 247 ? 143.902 133.066 128.006 1.00 23.65  ? 321 PRO A N   1 
ATOM   1586 C CA  . PRO A 1 247 ? 143.408 131.958 128.841 1.00 15.62  ? 321 PRO A CA  1 
ATOM   1587 C C   . PRO A 1 247 ? 142.855 132.409 130.183 1.00 27.02  ? 321 PRO A C   1 
ATOM   1588 O O   . PRO A 1 247 ? 141.811 131.904 130.617 1.00 31.66  ? 321 PRO A O   1 
ATOM   1589 C CB  . PRO A 1 247 ? 144.650 131.075 129.005 1.00 19.15  ? 321 PRO A CB  1 
ATOM   1590 C CG  . PRO A 1 247 ? 145.436 131.326 127.775 1.00 22.76  ? 321 PRO A CG  1 
ATOM   1591 C CD  . PRO A 1 247 ? 145.236 132.778 127.450 1.00 27.55  ? 321 PRO A CD  1 
ATOM   1592 N N   . THR A 1 248 ? 143.510 133.367 130.845 1.00 31.22  ? 322 THR A N   1 
ATOM   1593 C CA  . THR A 1 248 ? 143.021 133.837 132.137 1.00 27.87  ? 322 THR A CA  1 
ATOM   1594 C C   . THR A 1 248 ? 141.713 134.604 132.012 1.00 28.52  ? 322 THR A C   1 
ATOM   1595 O O   . THR A 1 248 ? 141.014 134.781 133.015 1.00 39.74  ? 322 THR A O   1 
ATOM   1596 C CB  . THR A 1 248 ? 144.075 134.708 132.827 1.00 26.98  ? 322 THR A CB  1 
ATOM   1597 O OG1 . THR A 1 248 ? 143.647 135.012 134.161 1.00 32.63  ? 322 THR A OG1 1 
ATOM   1598 C CG2 . THR A 1 248 ? 144.286 136.004 132.070 1.00 31.08  ? 322 THR A CG2 1 
ATOM   1599 N N   . GLY A 1 249 ? 141.370 135.063 130.814 1.00 24.73  ? 323 GLY A N   1 
ATOM   1600 C CA  . GLY A 1 249 ? 140.082 135.653 130.535 1.00 20.99  ? 323 GLY A CA  1 
ATOM   1601 C C   . GLY A 1 249 ? 139.044 134.675 130.036 1.00 25.71  ? 323 GLY A C   1 
ATOM   1602 O O   . GLY A 1 249 ? 137.946 135.095 129.657 1.00 35.14  ? 323 GLY A O   1 
ATOM   1603 N N   . SER A 1 250 ? 139.363 133.378 130.011 1.00 31.68  ? 324 SER A N   1 
ATOM   1604 C CA  . SER A 1 250 ? 138.394 132.387 129.556 1.00 26.93  ? 324 SER A CA  1 
ATOM   1605 C C   . SER A 1 250 ? 137.196 132.311 130.492 1.00 28.48  ? 324 SER A C   1 
ATOM   1606 O O   . SER A 1 250 ? 136.052 132.207 130.038 1.00 38.90  ? 324 SER A O   1 
ATOM   1607 C CB  . SER A 1 250 ? 139.061 131.020 129.436 1.00 31.09  ? 324 SER A CB  1 
ATOM   1608 O OG  . SER A 1 250 ? 139.461 130.536 130.705 1.00 34.08  ? 324 SER A OG  1 
ATOM   1609 N N   . THR A 1 251 ? 137.440 132.362 131.801 1.00 34.08  ? 325 THR A N   1 
ATOM   1610 C CA  . THR A 1 251 ? 136.370 132.328 132.789 1.00 31.19  ? 325 THR A CA  1 
ATOM   1611 C C   . THR A 1 251 ? 135.674 133.673 132.942 1.00 29.50  ? 325 THR A C   1 
ATOM   1612 O O   . THR A 1 251 ? 134.681 133.764 133.672 1.00 35.94  ? 325 THR A O   1 
ATOM   1613 C CB  . THR A 1 251 ? 136.925 131.872 134.140 1.00 30.34  ? 325 THR A CB  1 
ATOM   1614 O OG1 . THR A 1 251 ? 137.871 132.834 134.618 1.00 38.06  ? 325 THR A OG1 1 
ATOM   1615 C CG2 . THR A 1 251 ? 137.621 130.530 133.997 1.00 27.08  ? 325 THR A CG2 1 
ATOM   1616 N N   . ALA A 1 252 ? 136.174 134.707 132.271 1.00 33.42  ? 326 ALA A N   1 
ATOM   1617 C CA  . ALA A 1 252 ? 135.568 136.031 132.230 1.00 30.27  ? 326 ALA A CA  1 
ATOM   1618 C C   . ALA A 1 252 ? 134.424 136.065 131.226 1.00 34.33  ? 326 ALA A C   1 
ATOM   1619 O O   . ALA A 1 252 ? 133.876 135.019 130.862 1.00 40.64  ? 326 ALA A O   1 
ATOM   1620 C CB  . ALA A 1 252 ? 136.613 137.093 131.886 1.00 33.34  ? 326 ALA A CB  1 
ATOM   1621 N N   . TYR A 1 253 ? 134.048 137.270 130.797 1.00 31.70  ? 327 TYR A N   1 
ATOM   1622 C CA  . TYR A 1 253 ? 132.963 137.527 129.852 1.00 25.53  ? 327 TYR A CA  1 
ATOM   1623 C C   . TYR A 1 253 ? 132.961 136.567 128.666 1.00 29.23  ? 327 TYR A C   1 
ATOM   1624 O O   . TYR A 1 253 ? 131.915 136.347 128.047 1.00 41.85  ? 327 TYR A O   1 
ATOM   1625 C CB  . TYR A 1 253 ? 133.060 138.982 129.378 1.00 32.83  ? 327 TYR A CB  1 
ATOM   1626 C CG  . TYR A 1 253 ? 132.026 139.433 128.373 1.00 34.14  ? 327 TYR A CG  1 
ATOM   1627 C CD1 . TYR A 1 253 ? 130.675 139.410 128.678 1.00 39.97  ? 327 TYR A CD1 1 
ATOM   1628 C CD2 . TYR A 1 253 ? 132.409 139.967 127.152 1.00 34.68  ? 327 TYR A CD2 1 
ATOM   1629 C CE1 . TYR A 1 253 ? 129.729 139.846 127.775 1.00 35.30  ? 327 TYR A CE1 1 
ATOM   1630 C CE2 . TYR A 1 253 ? 131.470 140.412 126.242 1.00 36.26  ? 327 TYR A CE2 1 
ATOM   1631 C CZ  . TYR A 1 253 ? 130.132 140.347 126.558 1.00 37.49  ? 327 TYR A CZ  1 
ATOM   1632 O OH  . TYR A 1 253 ? 129.191 140.788 125.658 1.00 43.98  ? 327 TYR A OH  1 
ATOM   1633 N N   . ALA A 1 254 ? 134.122 135.996 128.336 1.00 31.35  ? 328 ALA A N   1 
ATOM   1634 C CA  . ALA A 1 254 ? 134.161 134.924 127.346 1.00 25.69  ? 328 ALA A CA  1 
ATOM   1635 C C   . ALA A 1 254 ? 133.348 133.718 127.802 1.00 29.89  ? 328 ALA A C   1 
ATOM   1636 O O   . ALA A 1 254 ? 132.606 133.126 127.009 1.00 35.09  ? 328 ALA A O   1 
ATOM   1637 C CB  . ALA A 1 254 ? 135.608 134.521 127.067 1.00 32.22  ? 328 ALA A CB  1 
ATOM   1638 N N   . ALA A 1 255 ? 133.466 133.344 129.080 1.00 33.14  ? 329 ALA A N   1 
ATOM   1639 C CA  . ALA A 1 255 ? 132.722 132.196 129.594 1.00 25.74  ? 329 ALA A CA  1 
ATOM   1640 C C   . ALA A 1 255 ? 131.220 132.414 129.513 1.00 32.28  ? 329 ALA A C   1 
ATOM   1641 O O   . ALA A 1 255 ? 130.469 131.470 129.243 1.00 40.76  ? 329 ALA A O   1 
ATOM   1642 C CB  . ALA A 1 255 ? 133.123 131.903 131.038 1.00 31.51  ? 329 ALA A CB  1 
ATOM   1643 N N   . ALA A 1 256 ? 130.762 133.644 129.753 1.00 34.07  ? 330 ALA A N   1 
ATOM   1644 C CA  . ALA A 1 256 ? 129.336 133.933 129.679 1.00 25.36  ? 330 ALA A CA  1 
ATOM   1645 C C   . ALA A 1 256 ? 128.788 133.710 128.277 1.00 31.42  ? 330 ALA A C   1 
ATOM   1646 O O   . ALA A 1 256 ? 127.595 133.433 128.112 1.00 37.63  ? 330 ALA A O   1 
ATOM   1647 C CB  . ALA A 1 256 ? 129.070 135.367 130.133 1.00 31.46  ? 330 ALA A CB  1 
ATOM   1648 N N   . ALA A 1 257 ? 129.641 133.806 127.260 1.00 31.14  ? 331 ALA A N   1 
ATOM   1649 C CA  . ALA A 1 257 ? 129.227 133.665 125.873 1.00 28.23  ? 331 ALA A CA  1 
ATOM   1650 C C   . ALA A 1 257 ? 129.338 132.236 125.359 1.00 30.18  ? 331 ALA A C   1 
ATOM   1651 O O   . ALA A 1 257 ? 129.139 132.006 124.161 1.00 37.29  ? 331 ALA A O   1 
ATOM   1652 C CB  . ALA A 1 257 ? 130.048 134.599 124.986 1.00 31.07  ? 331 ALA A CB  1 
ATOM   1653 N N   . GLY A 1 258 ? 129.650 131.277 126.223 1.00 26.24  ? 332 GLY A N   1 
ATOM   1654 C CA  . GLY A 1 258 ? 129.748 129.891 125.823 1.00 28.29  ? 332 GLY A CA  1 
ATOM   1655 C C   . GLY A 1 258 ? 131.150 129.354 125.644 1.00 30.87  ? 332 GLY A C   1 
ATOM   1656 O O   . GLY A 1 258 ? 131.303 128.238 125.136 1.00 35.21  ? 332 GLY A O   1 
ATOM   1657 N N   . ALA A 1 259 ? 132.173 130.106 126.039 1.00 31.44  ? 333 ALA A N   1 
ATOM   1658 C CA  . ALA A 1 259 ? 133.543 129.649 125.883 1.00 28.69  ? 333 ALA A CA  1 
ATOM   1659 C C   . ALA A 1 259 ? 133.865 128.539 126.880 1.00 34.54  ? 333 ALA A C   1 
ATOM   1660 O O   . ALA A 1 259 ? 133.257 128.425 127.948 1.00 43.65  ? 333 ALA A O   1 
ATOM   1661 C CB  . ALA A 1 259 ? 134.518 130.811 126.067 1.00 34.89  ? 333 ALA A CB  1 
ATOM   1662 N N   . SER A 1 260 ? 134.839 127.712 126.512 1.00 31.38  ? 334 SER A N   1 
ATOM   1663 C CA  . SER A 1 260 ? 135.299 126.642 127.381 1.00 26.42  ? 334 SER A CA  1 
ATOM   1664 C C   . SER A 1 260 ? 136.235 127.194 128.455 1.00 32.97  ? 334 SER A C   1 
ATOM   1665 O O   . SER A 1 260 ? 136.740 128.316 128.366 1.00 36.16  ? 334 SER A O   1 
ATOM   1666 C CB  . SER A 1 260 ? 136.002 125.557 126.567 1.00 30.37  ? 334 SER A CB  1 
ATOM   1667 O OG  . SER A 1 260 ? 135.108 124.938 125.660 1.00 38.00  ? 334 SER A OG  1 
ATOM   1668 N N   . MET A 1 261 ? 136.466 126.383 129.484 1.00 37.64  ? 335 MET A N   1 
ATOM   1669 C CA  . MET A 1 261 ? 137.349 126.756 130.580 1.00 28.44  ? 335 MET A CA  1 
ATOM   1670 C C   . MET A 1 261 ? 138.786 126.477 130.156 1.00 31.15  ? 335 MET A C   1 
ATOM   1671 O O   . MET A 1 261 ? 139.135 125.331 129.856 1.00 33.87  ? 335 MET A O   1 
ATOM   1672 C CB  . MET A 1 261 ? 137.002 125.974 131.846 1.00 35.16  ? 335 MET A CB  1 
ATOM   1673 C CG  . MET A 1 261 ? 135.625 126.270 132.431 1.00 32.90  ? 335 MET A CG  1 
ATOM   1674 S SD  . MET A 1 261 ? 135.374 127.973 132.950 1.00 54.23  ? 335 MET A SD  1 
ATOM   1675 C CE  . MET A 1 261 ? 134.398 128.596 131.588 1.00 35.79  ? 335 MET A CE  1 
ATOM   1676 N N   . ILE A 1 262 ? 139.614 127.517 130.131 1.00 37.26  ? 336 ILE A N   1 
ATOM   1677 C CA  . ILE A 1 262 ? 140.976 127.422 129.618 1.00 34.10  ? 336 ILE A CA  1 
ATOM   1678 C C   . ILE A 1 262 ? 141.934 127.638 130.782 1.00 35.75  ? 336 ILE A C   1 
ATOM   1679 O O   . ILE A 1 262 ? 141.886 128.679 131.449 1.00 42.02  ? 336 ILE A O   1 
ATOM   1680 C CB  . ILE A 1 262 ? 141.232 128.446 128.503 1.00 32.54  ? 336 ILE A CB  1 
ATOM   1681 C CG1 . ILE A 1 262 ? 140.254 128.249 127.342 1.00 34.51  ? 336 ILE A CG1 1 
ATOM   1682 C CG2 . ILE A 1 262 ? 142.645 128.317 127.987 1.00 29.62  ? 336 ILE A CG2 1 
ATOM   1683 C CD1 . ILE A 1 262 ? 140.327 126.919 126.658 1.00 36.17  ? 336 ILE A CD1 1 
ATOM   1684 N N   . HIS A 1 263 ? 142.798 126.658 131.029 1.00 26.12  ? 337 HIS A N   1 
ATOM   1685 C CA  . HIS A 1 263 ? 143.771 126.779 132.104 1.00 22.83  ? 337 HIS A CA  1 
ATOM   1686 C C   . HIS A 1 263 ? 144.843 127.801 131.726 1.00 31.13  ? 337 HIS A C   1 
ATOM   1687 O O   . HIS A 1 263 ? 145.304 127.823 130.581 1.00 41.24  ? 337 HIS A O   1 
ATOM   1688 C CB  . HIS A 1 263 ? 144.409 125.420 132.397 1.00 24.45  ? 337 HIS A CB  1 
ATOM   1689 C CG  . HIS A 1 263 ? 145.110 125.347 133.718 1.00 27.90  ? 337 HIS A CG  1 
ATOM   1690 N ND1 . HIS A 1 263 ? 146.265 126.047 133.991 1.00 31.13  ? 337 HIS A ND1 1 
ATOM   1691 C CD2 . HIS A 1 263 ? 144.817 124.653 134.843 1.00 24.83  ? 337 HIS A CD2 1 
ATOM   1692 C CE1 . HIS A 1 263 ? 146.651 125.790 135.227 1.00 26.93  ? 337 HIS A CE1 1 
ATOM   1693 N NE2 . HIS A 1 263 ? 145.790 124.946 135.766 1.00 26.30  ? 337 HIS A NE2 1 
ATOM   1694 N N   . PRO A 1 264 ? 145.261 128.660 132.662 1.00 26.09  ? 338 PRO A N   1 
ATOM   1695 C CA  . PRO A 1 264 ? 146.232 129.712 132.325 1.00 19.69  ? 338 PRO A CA  1 
ATOM   1696 C C   . PRO A 1 264 ? 147.630 129.211 131.994 1.00 21.16  ? 338 PRO A C   1 
ATOM   1697 O O   . PRO A 1 264 ? 148.501 130.035 131.694 1.00 29.25  ? 338 PRO A O   1 
ATOM   1698 C CB  . PRO A 1 264 ? 146.249 130.584 133.591 1.00 21.54  ? 338 PRO A CB  1 
ATOM   1699 C CG  . PRO A 1 264 ? 145.769 129.681 134.674 1.00 20.68  ? 338 PRO A CG  1 
ATOM   1700 C CD  . PRO A 1 264 ? 144.725 128.834 134.022 1.00 32.37  ? 338 PRO A CD  1 
ATOM   1701 N N   . ASN A 1 265 ? 147.887 127.905 132.034 1.00 21.80  ? 339 ASN A N   1 
ATOM   1702 C CA  . ASN A 1 265 ? 149.196 127.365 131.692 1.00 24.76  ? 339 ASN A CA  1 
ATOM   1703 C C   . ASN A 1 265 ? 149.259 126.799 130.279 1.00 29.24  ? 339 ASN A C   1 
ATOM   1704 O O   . ASN A 1 265 ? 150.260 126.171 129.921 1.00 37.19  ? 339 ASN A O   1 
ATOM   1705 C CB  . ASN A 1 265 ? 149.614 126.292 132.700 1.00 31.11  ? 339 ASN A CB  1 
ATOM   1706 C CG  . ASN A 1 265 ? 150.072 126.878 134.020 1.00 32.70  ? 339 ASN A CG  1 
ATOM   1707 O OD1 . ASN A 1 265 ? 149.749 126.356 135.086 1.00 40.93  ? 339 ASN A OD1 1 
ATOM   1708 N ND2 . ASN A 1 265 ? 150.813 127.977 133.957 1.00 32.41  ? 339 ASN A ND2 1 
ATOM   1709 N N   . VAL A 1 266 ? 148.222 126.998 129.471 1.00 28.81  ? 340 VAL A N   1 
ATOM   1710 C CA  . VAL A 1 266 ? 148.273 126.592 128.068 1.00 24.46  ? 340 VAL A CA  1 
ATOM   1711 C C   . VAL A 1 266 ? 148.497 127.836 127.215 1.00 31.13  ? 340 VAL A C   1 
ATOM   1712 O O   . VAL A 1 266 ? 147.866 128.877 127.451 1.00 34.83  ? 340 VAL A O   1 
ATOM   1713 C CB  . VAL A 1 266 ? 147.008 125.819 127.652 1.00 17.11  ? 340 VAL A CB  1 
ATOM   1714 C CG1 . VAL A 1 266 ? 146.751 124.673 128.613 1.00 24.83  ? 340 VAL A CG1 1 
ATOM   1715 C CG2 . VAL A 1 266 ? 145.796 126.725 127.581 1.00 24.97  ? 340 VAL A CG2 1 
ATOM   1716 N N   . PRO A 1 267 ? 149.421 127.799 126.256 1.00 23.18  ? 341 PRO A N   1 
ATOM   1717 C CA  . PRO A 1 267 ? 149.619 128.945 125.357 1.00 26.62  ? 341 PRO A CA  1 
ATOM   1718 C C   . PRO A 1 267 ? 148.579 128.951 124.248 1.00 28.99  ? 341 PRO A C   1 
ATOM   1719 O O   . PRO A 1 267 ? 148.619 128.125 123.331 1.00 34.21  ? 341 PRO A O   1 
ATOM   1720 C CB  . PRO A 1 267 ? 151.037 128.713 124.815 1.00 28.52  ? 341 PRO A CB  1 
ATOM   1721 C CG  . PRO A 1 267 ? 151.200 127.232 124.860 1.00 29.74  ? 341 PRO A CG  1 
ATOM   1722 C CD  . PRO A 1 267 ? 150.476 126.783 126.098 1.00 21.29  ? 341 PRO A CD  1 
ATOM   1723 N N   . ALA A 1 268 ? 147.642 129.894 124.326 1.00 24.05  ? 342 ALA A N   1 
ATOM   1724 C CA  . ALA A 1 268 ? 146.551 129.938 123.365 1.00 15.41  ? 342 ALA A CA  1 
ATOM   1725 C C   . ALA A 1 268 ? 145.912 131.318 123.374 1.00 24.84  ? 342 ALA A C   1 
ATOM   1726 O O   . ALA A 1 268 ? 146.089 132.101 124.311 1.00 36.91  ? 342 ALA A O   1 
ATOM   1727 C CB  . ALA A 1 268 ? 145.502 128.865 123.670 1.00 26.24  ? 342 ALA A CB  1 
ATOM   1728 N N   . ILE A 1 269 ? 145.168 131.603 122.308 1.00 26.34  ? 343 ILE A N   1 
ATOM   1729 C CA  . ILE A 1 269 ? 144.328 132.791 122.207 1.00 20.42  ? 343 ILE A CA  1 
ATOM   1730 C C   . ILE A 1 269 ? 142.929 132.335 121.823 1.00 26.27  ? 343 ILE A C   1 
ATOM   1731 O O   . ILE A 1 269 ? 142.761 131.590 120.852 1.00 31.62  ? 343 ILE A O   1 
ATOM   1732 C CB  . ILE A 1 269 ? 144.866 133.797 121.171 1.00 18.08  ? 343 ILE A CB  1 
ATOM   1733 C CG1 . ILE A 1 269 ? 146.254 134.301 121.567 1.00 27.07  ? 343 ILE A CG1 1 
ATOM   1734 C CG2 . ILE A 1 269 ? 143.907 134.964 121.015 1.00 27.50  ? 343 ILE A CG2 1 
ATOM   1735 C CD1 . ILE A 1 269 ? 146.841 135.276 120.572 1.00 25.79  ? 343 ILE A CD1 1 
ATOM   1736 N N   . MET A 1 270 ? 141.929 132.778 122.572 1.00 25.09  ? 344 MET A N   1 
ATOM   1737 C CA  . MET A 1 270 ? 140.559 132.390 122.282 1.00 16.30  ? 344 MET A CA  1 
ATOM   1738 C C   . MET A 1 270 ? 139.892 133.402 121.363 1.00 26.29  ? 344 MET A C   1 
ATOM   1739 O O   . MET A 1 270 ? 140.261 134.578 121.328 1.00 36.02  ? 344 MET A O   1 
ATOM   1740 C CB  . MET A 1 270 ? 139.738 132.258 123.563 1.00 27.89  ? 344 MET A CB  1 
ATOM   1741 C CG  . MET A 1 270 ? 140.105 131.079 124.428 1.00 33.62  ? 344 MET A CG  1 
ATOM   1742 S SD  . MET A 1 270 ? 138.727 130.686 125.510 1.00 54.29  ? 344 MET A SD  1 
ATOM   1743 C CE  . MET A 1 270 ? 137.503 130.236 124.284 1.00 38.32  ? 344 MET A CE  1 
ATOM   1744 N N   . ILE A 1 271 ? 138.905 132.926 120.605 1.00 28.35  ? 345 ILE A N   1 
ATOM   1745 C CA  . ILE A 1 271 ? 138.016 133.782 119.830 1.00 17.58  ? 345 ILE A CA  1 
ATOM   1746 C C   . ILE A 1 271 ? 136.606 133.253 120.052 1.00 21.70  ? 345 ILE A C   1 
ATOM   1747 O O   . ILE A 1 271 ? 136.253 132.184 119.538 1.00 28.84  ? 345 ILE A O   1 
ATOM   1748 C CB  . ILE A 1 271 ? 138.356 133.801 118.333 1.00 16.54  ? 345 ILE A CB  1 
ATOM   1749 C CG1 . ILE A 1 271 ? 139.758 134.368 118.105 1.00 22.06  ? 345 ILE A CG1 1 
ATOM   1750 C CG2 . ILE A 1 271 ? 137.331 134.621 117.568 1.00 24.42  ? 345 ILE A CG2 1 
ATOM   1751 C CD1 . ILE A 1 271 ? 140.269 134.174 116.698 1.00 29.12  ? 345 ILE A CD1 1 
ATOM   1752 N N   . THR A 1 272 ? 135.806 133.984 120.826 1.00 30.90  ? 346 THR A N   1 
ATOM   1753 C CA  . THR A 1 272 ? 134.437 133.591 121.104 1.00 30.53  ? 346 THR A CA  1 
ATOM   1754 C C   . THR A 1 272 ? 133.500 134.764 120.851 1.00 25.67  ? 346 THR A C   1 
ATOM   1755 O O   . THR A 1 272 ? 133.848 135.919 121.130 1.00 33.29  ? 346 THR A O   1 
ATOM   1756 C CB  . THR A 1 272 ? 134.286 133.077 122.550 1.00 27.45  ? 346 THR A CB  1 
ATOM   1757 O OG1 . THR A 1 272 ? 132.943 132.630 122.774 1.00 34.72  ? 346 THR A OG1 1 
ATOM   1758 C CG2 . THR A 1 272 ? 134.647 134.142 123.561 1.00 31.63  ? 346 THR A CG2 1 
ATOM   1759 N N   . PRO A 1 273 ? 132.315 134.500 120.305 1.00 25.69  ? 347 PRO A N   1 
ATOM   1760 C CA  . PRO A 1 273 ? 131.423 135.589 119.891 1.00 29.23  ? 347 PRO A CA  1 
ATOM   1761 C C   . PRO A 1 273 ? 130.578 136.157 121.014 1.00 31.71  ? 347 PRO A C   1 
ATOM   1762 O O   . PRO A 1 273 ? 130.773 135.831 122.188 1.00 38.27  ? 347 PRO A O   1 
ATOM   1763 C CB  . PRO A 1 273 ? 130.532 134.911 118.852 1.00 29.51  ? 347 PRO A CB  1 
ATOM   1764 C CG  . PRO A 1 273 ? 130.428 133.513 119.372 1.00 32.40  ? 347 PRO A CG  1 
ATOM   1765 C CD  . PRO A 1 273 ? 131.805 133.187 119.874 1.00 33.77  ? 347 PRO A CD  1 
ATOM   1766 N N   . ILE A 1 274 ? 129.635 137.023 120.649 1.00 27.73  ? 348 ILE A N   1 
ATOM   1767 C CA  . ILE A 1 274 ? 128.597 137.503 121.559 1.00 24.75  ? 348 ILE A CA  1 
ATOM   1768 C C   . ILE A 1 274 ? 127.281 137.369 120.797 1.00 37.36  ? 348 ILE A C   1 
ATOM   1769 O O   . ILE A 1 274 ? 126.896 138.262 120.035 1.00 46.25  ? 348 ILE A O   1 
ATOM   1770 C CB  . ILE A 1 274 ? 128.822 138.947 122.014 1.00 32.04  ? 348 ILE A CB  1 
ATOM   1771 C CG1 . ILE A 1 274 ? 130.229 139.129 122.567 1.00 28.08  ? 348 ILE A CG1 1 
ATOM   1772 C CG2 . ILE A 1 274 ? 127.823 139.308 123.100 1.00 37.62  ? 348 ILE A CG2 1 
ATOM   1773 C CD1 . ILE A 1 274 ? 130.642 140.574 122.722 1.00 33.90  ? 348 ILE A CD1 1 
ATOM   1774 N N   . CYS A 1 275 ? 126.587 136.249 120.993 1.00 32.50  ? 349 CYS A N   1 
ATOM   1775 C CA  . CYS A 1 275 ? 125.276 136.003 120.403 1.00 29.96  ? 349 CYS A CA  1 
ATOM   1776 C C   . CYS A 1 275 ? 125.275 136.200 118.889 1.00 34.68  ? 349 CYS A C   1 
ATOM   1777 O O   . CYS A 1 275 ? 124.714 137.186 118.395 1.00 38.52  ? 349 CYS A O   1 
ATOM   1778 C CB  . CYS A 1 275 ? 124.229 136.915 121.048 1.00 33.10  ? 349 CYS A CB  1 
ATOM   1779 S SG  . CYS A 1 275 ? 124.379 137.070 122.840 1.00 39.95  ? 349 CYS A SG  1 
ATOM   1780 N N   . PRO A 1 276 ? 125.888 135.300 118.124 1.00 29.60  ? 350 PRO A N   1 
ATOM   1781 C CA  . PRO A 1 276 ? 125.866 135.438 116.665 1.00 30.66  ? 350 PRO A CA  1 
ATOM   1782 C C   . PRO A 1 276 ? 124.503 135.079 116.098 1.00 37.50  ? 350 PRO A C   1 
ATOM   1783 O O   . PRO A 1 276 ? 123.724 134.334 116.695 1.00 42.56  ? 350 PRO A O   1 
ATOM   1784 C CB  . PRO A 1 276 ? 126.929 134.438 116.190 1.00 32.33  ? 350 PRO A CB  1 
ATOM   1785 C CG  . PRO A 1 276 ? 127.533 133.854 117.435 1.00 35.96  ? 350 PRO A CG  1 
ATOM   1786 C CD  . PRO A 1 276 ? 126.546 134.052 118.531 1.00 31.70  ? 350 PRO A CD  1 
ATOM   1787 N N   . HIS A 1 277 ? 124.228 135.607 114.910 1.00 38.45  ? 351 HIS A N   1 
ATOM   1788 C CA  . HIS A 1 277 ? 123.043 135.185 114.166 1.00 35.22  ? 351 HIS A CA  1 
ATOM   1789 C C   . HIS A 1 277 ? 123.354 133.980 113.285 1.00 35.57  ? 351 HIS A C   1 
ATOM   1790 O O   . HIS A 1 277 ? 123.049 133.944 112.094 1.00 41.44  ? 351 HIS A O   1 
ATOM   1791 C CB  . HIS A 1 277 ? 122.489 136.341 113.344 1.00 40.79  ? 351 HIS A CB  1 
ATOM   1792 C CG  . HIS A 1 277 ? 121.016 136.243 113.092 1.00 47.50  ? 351 HIS A CG  1 
ATOM   1793 N ND1 . HIS A 1 277 ? 120.091 136.173 114.111 1.00 43.49  ? 351 HIS A ND1 1 
ATOM   1794 C CD2 . HIS A 1 277 ? 120.309 136.193 111.939 1.00 46.00  ? 351 HIS A CD2 1 
ATOM   1795 C CE1 . HIS A 1 277 ? 118.878 136.088 113.597 1.00 43.73  ? 351 HIS A CE1 1 
ATOM   1796 N NE2 . HIS A 1 277 ? 118.982 136.099 112.281 1.00 48.11  ? 351 HIS A NE2 1 
ATOM   1797 N N   . SER A 1 278 ? 123.972 132.973 113.896 1.00 33.93  ? 352 SER A N   1 
ATOM   1798 C CA  . SER A 1 278 ? 124.300 131.727 113.219 1.00 31.11  ? 352 SER A CA  1 
ATOM   1799 C C   . SER A 1 278 ? 124.461 130.652 114.279 1.00 35.06  ? 352 SER A C   1 
ATOM   1800 O O   . SER A 1 278 ? 125.124 130.880 115.295 1.00 43.41  ? 352 SER A O   1 
ATOM   1801 C CB  . SER A 1 278 ? 125.580 131.860 112.389 1.00 32.20  ? 352 SER A CB  1 
ATOM   1802 O OG  . SER A 1 278 ? 126.686 132.199 113.207 1.00 42.69  ? 352 SER A OG  1 
ATOM   1803 N N   . LEU A 1 279 ? 123.859 129.490 114.045 1.00 32.33  ? 353 LEU A N   1 
ATOM   1804 C CA  . LEU A 1 279 ? 123.913 128.413 115.022 1.00 37.92  ? 353 LEU A CA  1 
ATOM   1805 C C   . LEU A 1 279 ? 125.232 127.652 115.000 1.00 40.42  ? 353 LEU A C   1 
ATOM   1806 O O   . LEU A 1 279 ? 125.451 126.808 115.875 1.00 41.59  ? 353 LEU A O   1 
ATOM   1807 C CB  . LEU A 1 279 ? 122.756 127.439 114.792 1.00 40.16  ? 353 LEU A CB  1 
ATOM   1808 C CG  . LEU A 1 279 ? 121.417 128.042 114.361 1.00 38.17  ? 353 LEU A CG  1 
ATOM   1809 C CD1 . LEU A 1 279 ? 120.433 126.947 113.983 1.00 41.53  ? 353 LEU A CD1 1 
ATOM   1810 C CD2 . LEU A 1 279 ? 120.844 128.920 115.460 1.00 38.29  ? 353 LEU A CD2 1 
ATOM   1811 N N   . SER A 1 280 ? 126.118 127.938 114.046 1.00 41.73  ? 354 SER A N   1 
ATOM   1812 C CA  . SER A 1 280 ? 127.316 127.136 113.836 1.00 38.62  ? 354 SER A CA  1 
ATOM   1813 C C   . SER A 1 280 ? 128.593 127.772 114.369 1.00 40.30  ? 354 SER A C   1 
ATOM   1814 O O   . SER A 1 280 ? 129.607 127.074 114.475 1.00 45.99  ? 354 SER A O   1 
ATOM   1815 C CB  . SER A 1 280 ? 127.503 126.847 112.341 1.00 43.75  ? 354 SER A CB  1 
ATOM   1816 O OG  . SER A 1 280 ? 126.451 126.053 111.829 1.00 44.30  ? 354 SER A OG  1 
ATOM   1817 N N   . PHE A 1 281 ? 128.582 129.061 114.709 1.00 36.98  ? 355 PHE A N   1 
ATOM   1818 C CA  . PHE A 1 281 ? 129.827 129.768 115.007 1.00 36.49  ? 355 PHE A CA  1 
ATOM   1819 C C   . PHE A 1 281 ? 130.234 129.445 116.444 1.00 33.51  ? 355 PHE A C   1 
ATOM   1820 O O   . PHE A 1 281 ? 130.040 130.224 117.381 1.00 37.87  ? 355 PHE A O   1 
ATOM   1821 C CB  . PHE A 1 281 ? 129.673 131.266 114.775 1.00 32.91  ? 355 PHE A CB  1 
ATOM   1822 C CG  . PHE A 1 281 ? 130.935 132.049 115.012 1.00 40.48  ? 355 PHE A CG  1 
ATOM   1823 C CD1 . PHE A 1 281 ? 131.958 132.024 114.083 1.00 43.61  ? 355 PHE A CD1 1 
ATOM   1824 C CD2 . PHE A 1 281 ? 131.098 132.812 116.147 1.00 40.59  ? 355 PHE A CD2 1 
ATOM   1825 C CE1 . PHE A 1 281 ? 133.118 132.743 114.285 1.00 40.71  ? 355 PHE A CE1 1 
ATOM   1826 C CE2 . PHE A 1 281 ? 132.264 133.530 116.354 1.00 38.44  ? 355 PHE A CE2 1 
ATOM   1827 C CZ  . PHE A 1 281 ? 133.271 133.494 115.423 1.00 37.34  ? 355 PHE A CZ  1 
ATOM   1828 N N   . ARG A 1 282 ? 130.796 128.252 116.610 1.00 34.70  ? 356 ARG A N   1 
ATOM   1829 C CA  . ARG A 1 282 ? 131.312 127.824 117.898 1.00 27.87  ? 356 ARG A CA  1 
ATOM   1830 C C   . ARG A 1 282 ? 132.631 128.539 118.196 1.00 34.94  ? 356 ARG A C   1 
ATOM   1831 O O   . ARG A 1 282 ? 133.412 128.818 117.283 1.00 44.48  ? 356 ARG A O   1 
ATOM   1832 C CB  . ARG A 1 282 ? 131.517 126.310 117.895 1.00 27.43  ? 356 ARG A CB  1 
ATOM   1833 C CG  . ARG A 1 282 ? 131.741 125.665 119.250 1.00 35.77  ? 356 ARG A CG  1 
ATOM   1834 C CD  . ARG A 1 282 ? 131.281 124.220 119.244 1.00 35.28  ? 356 ARG A CD  1 
ATOM   1835 N NE  . ARG A 1 282 ? 129.830 124.106 119.190 1.00 32.74  ? 356 ARG A NE  1 
ATOM   1836 C CZ  . ARG A 1 282 ? 129.170 122.956 119.188 1.00 34.02  ? 356 ARG A CZ  1 
ATOM   1837 N NH1 . ARG A 1 282 ? 129.804 121.796 119.237 1.00 35.73  ? 356 ARG A NH1 1 
ATOM   1838 N NH2 . ARG A 1 282 ? 127.842 122.970 119.135 1.00 39.67  ? 356 ARG A NH2 1 
ATOM   1839 N N   . PRO A 1 283 ? 132.898 128.859 119.465 1.00 32.62  ? 357 PRO A N   1 
ATOM   1840 C CA  . PRO A 1 283 ? 134.170 129.509 119.805 1.00 31.09  ? 357 PRO A CA  1 
ATOM   1841 C C   . PRO A 1 283 ? 135.366 128.643 119.440 1.00 28.53  ? 357 PRO A C   1 
ATOM   1842 O O   . PRO A 1 283 ? 135.306 127.412 119.474 1.00 31.54  ? 357 PRO A O   1 
ATOM   1843 C CB  . PRO A 1 283 ? 134.070 129.716 121.322 1.00 33.81  ? 357 PRO A CB  1 
ATOM   1844 C CG  . PRO A 1 283 ? 132.954 128.824 121.773 1.00 31.97  ? 357 PRO A CG  1 
ATOM   1845 C CD  . PRO A 1 283 ? 132.001 128.782 120.629 1.00 34.23  ? 357 PRO A CD  1 
ATOM   1846 N N   . ILE A 1 284 ? 136.467 129.308 119.083 1.00 24.87  ? 358 ILE A N   1 
ATOM   1847 C CA  . ILE A 1 284 ? 137.663 128.634 118.595 1.00 24.84  ? 358 ILE A CA  1 
ATOM   1848 C C   . ILE A 1 284 ? 138.864 129.042 119.438 1.00 31.18  ? 358 ILE A C   1 
ATOM   1849 O O   . ILE A 1 284 ? 138.858 130.063 120.130 1.00 39.64  ? 358 ILE A O   1 
ATOM   1850 C CB  . ILE A 1 284 ? 137.936 128.930 117.104 1.00 23.79  ? 358 ILE A CB  1 
ATOM   1851 C CG1 . ILE A 1 284 ? 138.432 130.365 116.925 1.00 25.60  ? 358 ILE A CG1 1 
ATOM   1852 C CG2 . ILE A 1 284 ? 136.690 128.681 116.268 1.00 29.40  ? 358 ILE A CG2 1 
ATOM   1853 C CD1 . ILE A 1 284 ? 138.839 130.697 115.509 1.00 32.60  ? 358 ILE A CD1 1 
ATOM   1854 N N   . VAL A 1 285 ? 139.903 128.212 119.375 1.00 29.35  ? 359 VAL A N   1 
ATOM   1855 C CA  . VAL A 1 285 ? 141.155 128.431 120.089 1.00 26.30  ? 359 VAL A CA  1 
ATOM   1856 C C   . VAL A 1 285 ? 142.296 128.345 119.084 1.00 28.96  ? 359 VAL A C   1 
ATOM   1857 O O   . VAL A 1 285 ? 142.380 127.379 118.318 1.00 41.00  ? 359 VAL A O   1 
ATOM   1858 C CB  . VAL A 1 285 ? 141.351 127.407 121.224 1.00 25.26  ? 359 VAL A CB  1 
ATOM   1859 C CG1 . VAL A 1 285 ? 142.622 127.700 121.987 1.00 31.45  ? 359 VAL A CG1 1 
ATOM   1860 C CG2 . VAL A 1 285 ? 140.154 127.416 122.162 1.00 29.72  ? 359 VAL A CG2 1 
ATOM   1861 N N   . VAL A 1 286 ? 143.171 129.346 119.089 1.00 23.80  ? 360 VAL A N   1 
ATOM   1862 C CA  . VAL A 1 286 ? 144.243 129.455 118.102 1.00 20.01  ? 360 VAL A CA  1 
ATOM   1863 C C   . VAL A 1 286 ? 145.575 129.526 118.837 1.00 25.96  ? 360 VAL A C   1 
ATOM   1864 O O   . VAL A 1 286 ? 145.625 129.861 120.032 1.00 35.94  ? 360 VAL A O   1 
ATOM   1865 C CB  . VAL A 1 286 ? 144.048 130.684 117.182 1.00 19.03  ? 360 VAL A CB  1 
ATOM   1866 C CG1 . VAL A 1 286 ? 142.649 130.693 116.592 1.00 23.37  ? 360 VAL A CG1 1 
ATOM   1867 C CG2 . VAL A 1 286 ? 144.314 131.969 117.946 1.00 29.21  ? 360 VAL A CG2 1 
ATOM   1868 N N   . PRO A 1 287 ? 146.675 129.193 118.157 1.00 23.16  ? 361 PRO A N   1 
ATOM   1869 C CA  . PRO A 1 287 ? 147.991 129.279 118.802 1.00 26.59  ? 361 PRO A CA  1 
ATOM   1870 C C   . PRO A 1 287 ? 148.329 130.705 119.207 1.00 25.96  ? 361 PRO A C   1 
ATOM   1871 O O   . PRO A 1 287 ? 147.882 131.675 118.592 1.00 34.55  ? 361 PRO A O   1 
ATOM   1872 C CB  . PRO A 1 287 ? 148.952 128.762 117.725 1.00 24.55  ? 361 PRO A CB  1 
ATOM   1873 C CG  . PRO A 1 287 ? 148.111 127.943 116.822 1.00 20.68  ? 361 PRO A CG  1 
ATOM   1874 C CD  . PRO A 1 287 ? 146.755 128.570 116.824 1.00 23.99  ? 361 PRO A CD  1 
ATOM   1875 N N   . ALA A 1 288 ? 149.133 130.822 120.266 1.00 24.90  ? 362 ALA A N   1 
ATOM   1876 C CA  . ALA A 1 288 ? 149.460 132.129 120.822 1.00 25.61  ? 362 ALA A CA  1 
ATOM   1877 C C   . ALA A 1 288 ? 150.424 132.922 119.949 1.00 22.03  ? 362 ALA A C   1 
ATOM   1878 O O   . ALA A 1 288 ? 150.605 134.121 120.183 1.00 34.21  ? 362 ALA A O   1 
ATOM   1879 C CB  . ALA A 1 288 ? 150.049 131.969 122.224 1.00 29.60  ? 362 ALA A CB  1 
ATOM   1880 N N   . GLY A 1 289 ? 151.041 132.294 118.954 1.00 24.20  ? 363 GLY A N   1 
ATOM   1881 C CA  . GLY A 1 289 ? 152.038 132.971 118.149 1.00 24.53  ? 363 GLY A CA  1 
ATOM   1882 C C   . GLY A 1 289 ? 151.513 133.548 116.851 1.00 29.09  ? 363 GLY A C   1 
ATOM   1883 O O   . GLY A 1 289 ? 152.288 133.797 115.923 1.00 36.41  ? 363 GLY A O   1 
ATOM   1884 N N   . VAL A 1 290 ? 150.206 133.770 116.769 1.00 28.80  ? 364 VAL A N   1 
ATOM   1885 C CA  . VAL A 1 290 ? 149.574 134.197 115.533 1.00 26.04  ? 364 VAL A CA  1 
ATOM   1886 C C   . VAL A 1 290 ? 149.276 135.689 115.591 1.00 21.14  ? 364 VAL A C   1 
ATOM   1887 O O   . VAL A 1 290 ? 149.320 136.327 116.646 1.00 34.15  ? 364 VAL A O   1 
ATOM   1888 C CB  . VAL A 1 290 ? 148.286 133.393 115.240 1.00 24.50  ? 364 VAL A CB  1 
ATOM   1889 C CG1 . VAL A 1 290 ? 148.581 131.903 115.225 1.00 31.00  ? 364 VAL A CG1 1 
ATOM   1890 C CG2 . VAL A 1 290 ? 147.215 133.724 116.259 1.00 25.13  ? 364 VAL A CG2 1 
ATOM   1891 N N   . GLU A 1 291 ? 148.968 136.251 114.425 1.00 32.41  ? 365 GLU A N   1 
ATOM   1892 C CA  . GLU A 1 291 ? 148.586 137.648 114.273 1.00 22.40  ? 365 GLU A CA  1 
ATOM   1893 C C   . GLU A 1 291 ? 147.084 137.733 114.041 1.00 29.40  ? 365 GLU A C   1 
ATOM   1894 O O   . GLU A 1 291 ? 146.554 137.065 113.148 1.00 41.61  ? 365 GLU A O   1 
ATOM   1895 C CB  . GLU A 1 291 ? 149.326 138.283 113.093 1.00 31.73  ? 365 GLU A CB  1 
ATOM   1896 C CG  . GLU A 1 291 ? 148.994 139.747 112.846 1.00 33.64  ? 365 GLU A CG  1 
ATOM   1897 C CD  . GLU A 1 291 ? 149.619 140.673 113.864 1.00 40.48  ? 365 GLU A CD  1 
ATOM   1898 O OE1 . GLU A 1 291 ? 150.703 140.334 114.378 1.00 39.33  ? 365 GLU A OE1 1 
ATOM   1899 O OE2 . GLU A 1 291 ? 149.028 141.735 114.152 1.00 41.63  ? 365 GLU A OE2 1 
ATOM   1900 N N   . LEU A 1 292 ? 146.401 138.550 114.838 1.00 22.69  ? 366 LEU A N   1 
ATOM   1901 C CA  . LEU A 1 292 ? 144.984 138.813 114.631 1.00 16.03  ? 366 LEU A CA  1 
ATOM   1902 C C   . LEU A 1 292 ? 144.793 140.257 114.193 1.00 24.82  ? 366 LEU A C   1 
ATOM   1903 O O   . LEU A 1 292 ? 145.465 141.158 114.699 1.00 34.73  ? 366 LEU A O   1 
ATOM   1904 C CB  . LEU A 1 292 ? 144.174 138.535 115.899 1.00 26.96  ? 366 LEU A CB  1 
ATOM   1905 C CG  . LEU A 1 292 ? 143.473 137.177 115.959 1.00 22.50  ? 366 LEU A CG  1 
ATOM   1906 C CD1 . LEU A 1 292 ? 144.480 136.046 115.924 1.00 27.23  ? 366 LEU A CD1 1 
ATOM   1907 C CD2 . LEU A 1 292 ? 142.602 137.078 117.196 1.00 28.90  ? 366 LEU A CD2 1 
ATOM   1908 N N   . LYS A 1 293 ? 143.883 140.479 113.248 1.00 22.33  ? 367 LYS A N   1 
ATOM   1909 C CA  . LYS A 1 293 ? 143.622 141.838 112.777 1.00 22.06  ? 367 LYS A CA  1 
ATOM   1910 C C   . LYS A 1 293 ? 142.132 141.965 112.492 1.00 23.15  ? 367 LYS A C   1 
ATOM   1911 O O   . LYS A 1 293 ? 141.611 141.307 111.591 1.00 38.50  ? 367 LYS A O   1 
ATOM   1912 C CB  . LYS A 1 293 ? 144.457 142.159 111.541 1.00 27.59  ? 367 LYS A CB  1 
ATOM   1913 C CG  . LYS A 1 293 ? 144.318 143.587 111.041 1.00 28.77  ? 367 LYS A CG  1 
ATOM   1914 C CD  . LYS A 1 293 ? 145.225 143.832 109.845 1.00 31.74  ? 367 LYS A CD  1 
ATOM   1915 C CE  . LYS A 1 293 ? 145.177 145.282 109.391 1.00 35.82  ? 367 LYS A CE  1 
ATOM   1916 N NZ  . LYS A 1 293 ? 143.863 145.669 108.822 1.00 37.76  ? 367 LYS A NZ  1 
ATOM   1917 N N   . ILE A 1 294 ? 141.456 142.820 113.249 1.00 23.08  ? 368 ILE A N   1 
ATOM   1918 C CA  . ILE A 1 294 ? 140.008 142.968 113.186 1.00 23.24  ? 368 ILE A CA  1 
ATOM   1919 C C   . ILE A 1 294 ? 139.682 144.336 112.604 1.00 30.00  ? 368 ILE A C   1 
ATOM   1920 O O   . ILE A 1 294 ? 140.277 145.349 113.000 1.00 36.09  ? 368 ILE A O   1 
ATOM   1921 C CB  . ILE A 1 294 ? 139.366 142.782 114.572 1.00 23.98  ? 368 ILE A CB  1 
ATOM   1922 C CG1 . ILE A 1 294 ? 139.617 141.359 115.075 1.00 27.29  ? 368 ILE A CG1 1 
ATOM   1923 C CG2 . ILE A 1 294 ? 137.876 143.077 114.520 1.00 31.04  ? 368 ILE A CG2 1 
ATOM   1924 C CD1 . ILE A 1 294 ? 138.845 140.996 116.319 1.00 28.11  ? 368 ILE A CD1 1 
ATOM   1925 N N   . MET A 1 295 ? 138.753 144.357 111.646 1.00 36.58  ? 369 MET A N   1 
ATOM   1926 C CA  . MET A 1 295 ? 138.306 145.594 111.019 1.00 28.96  ? 369 MET A CA  1 
ATOM   1927 C C   . MET A 1 295 ? 136.798 145.541 110.824 1.00 36.41  ? 369 MET A C   1 
ATOM   1928 O O   . MET A 1 295 ? 136.141 144.548 111.148 1.00 43.79  ? 369 MET A O   1 
ATOM   1929 C CB  . MET A 1 295 ? 138.986 145.829 109.666 1.00 32.18  ? 369 MET A CB  1 
ATOM   1930 C CG  . MET A 1 295 ? 140.395 146.367 109.733 1.00 39.68  ? 369 MET A CG  1 
ATOM   1931 S SD  . MET A 1 295 ? 141.106 146.419 108.080 1.00 50.28  ? 369 MET A SD  1 
ATOM   1932 C CE  . MET A 1 295 ? 141.057 144.683 107.654 1.00 39.99  ? 369 MET A CE  1 
ATOM   1933 N N   . LEU A 1 296 ? 136.249 146.623 110.279 1.00 40.90  ? 370 LEU A N   1 
ATOM   1934 C CA  . LEU A 1 296 ? 134.873 146.639 109.806 1.00 41.45  ? 370 LEU A CA  1 
ATOM   1935 C C   . LEU A 1 296 ? 134.834 146.235 108.339 1.00 48.54  ? 370 LEU A C   1 
ATOM   1936 O O   . LEU A 1 296 ? 135.668 146.671 107.541 1.00 55.54  ? 370 LEU A O   1 
ATOM   1937 C CB  . LEU A 1 296 ? 134.247 148.024 109.978 1.00 40.01  ? 370 LEU A CB  1 
ATOM   1938 C CG  . LEU A 1 296 ? 133.942 148.518 111.391 1.00 41.16  ? 370 LEU A CG  1 
ATOM   1939 C CD1 . LEU A 1 296 ? 133.477 149.960 111.354 1.00 46.02  ? 370 LEU A CD1 1 
ATOM   1940 C CD2 . LEU A 1 296 ? 132.886 147.646 112.036 1.00 44.28  ? 370 LEU A CD2 1 
ATOM   1941 N N   . SER A 1 297 ? 133.864 145.395 107.991 1.00 46.30  ? 371 SER A N   1 
ATOM   1942 C CA  . SER A 1 297 ? 133.713 144.980 106.608 1.00 45.27  ? 371 SER A CA  1 
ATOM   1943 C C   . SER A 1 297 ? 133.322 146.176 105.741 1.00 44.99  ? 371 SER A C   1 
ATOM   1944 O O   . SER A 1 297 ? 132.677 147.113 106.219 1.00 53.04  ? 371 SER A O   1 
ATOM   1945 C CB  . SER A 1 297 ? 132.663 143.879 106.490 1.00 50.18  ? 371 SER A CB  1 
ATOM   1946 O OG  . SER A 1 297 ? 131.377 144.356 106.839 1.00 54.32  ? 371 SER A OG  1 
ATOM   1947 N N   . PRO A 1 298 ? 133.727 146.182 104.467 1.00 38.57  ? 372 PRO A N   1 
ATOM   1948 C CA  . PRO A 1 298 ? 133.374 147.320 103.601 1.00 47.39  ? 372 PRO A CA  1 
ATOM   1949 C C   . PRO A 1 298 ? 131.878 147.556 103.495 1.00 53.51  ? 372 PRO A C   1 
ATOM   1950 O O   . PRO A 1 298 ? 131.438 148.711 103.443 1.00 54.54  ? 372 PRO A O   1 
ATOM   1951 C CB  . PRO A 1 298 ? 133.989 146.929 102.250 1.00 54.01  ? 372 PRO A CB  1 
ATOM   1952 C CG  . PRO A 1 298 ? 135.089 145.982 102.598 1.00 50.47  ? 372 PRO A CG  1 
ATOM   1953 C CD  . PRO A 1 298 ? 134.588 145.207 103.777 1.00 46.65  ? 372 PRO A CD  1 
ATOM   1954 N N   . GLU A 1 299 ? 131.082 146.493 103.462 1.00 59.35  ? 373 GLU A N   1 
ATOM   1955 C CA  . GLU A 1 299 ? 129.625 146.609 103.407 1.00 59.88  ? 373 GLU A CA  1 
ATOM   1956 C C   . GLU A 1 299 ? 129.022 146.425 104.798 1.00 60.72  ? 373 GLU A C   1 
ATOM   1957 O O   . GLU A 1 299 ? 128.282 145.480 105.070 1.00 62.56  ? 373 GLU A O   1 
ATOM   1958 C CB  . GLU A 1 299 ? 129.038 145.584 102.434 1.00 62.06  ? 373 GLU A CB  1 
ATOM   1959 C CG  . GLU A 1 299 ? 129.396 145.836 100.977 1.00 63.68  ? 373 GLU A CG  1 
ATOM   1960 C CD  . GLU A 1 299 ? 128.857 144.760 100.053 1.00 64.88  ? 373 GLU A CD  1 
ATOM   1961 O OE1 . GLU A 1 299 ? 128.373 143.727 100.560 1.00 65.09  ? 373 GLU A OE1 1 
ATOM   1962 O OE2 . GLU A 1 299 ? 128.920 144.948 98.820  1.00 62.94  ? 373 GLU A OE2 1 
ATOM   1963 N N   . ALA A 1 300 ? 129.351 147.356 105.691 1.00 57.75  ? 374 ALA A N   1 
ATOM   1964 C CA  . ALA A 1 300 ? 128.894 147.307 107.071 1.00 59.77  ? 374 ALA A CA  1 
ATOM   1965 C C   . ALA A 1 300 ? 128.240 148.624 107.454 1.00 60.53  ? 374 ALA A C   1 
ATOM   1966 O O   . ALA A 1 300 ? 128.767 149.700 107.156 1.00 58.95  ? 374 ALA A O   1 
ATOM   1967 C CB  . ALA A 1 300 ? 130.046 147.008 108.036 1.00 59.40  ? 374 ALA A CB  1 
ATOM   1968 N N   . ARG A 1 301 ? 127.091 148.530 108.113 1.00 69.58  ? 375 ARG A N   1 
ATOM   1969 C CA  . ARG A 1 301 ? 126.423 149.694 108.671 1.00 67.61  ? 375 ARG A CA  1 
ATOM   1970 C C   . ARG A 1 301 ? 126.934 149.954 110.082 1.00 68.07  ? 375 ARG A C   1 
ATOM   1971 O O   . ARG A 1 301 ? 127.375 149.037 110.781 1.00 70.30  ? 375 ARG A O   1 
ATOM   1972 C CB  . ARG A 1 301 ? 124.907 149.494 108.691 1.00 67.70  ? 375 ARG A CB  1 
ATOM   1973 C CG  . ARG A 1 301 ? 124.255 149.555 107.320 1.00 67.54  ? 375 ARG A CG  1 
ATOM   1974 C CD  . ARG A 1 301 ? 123.020 148.671 107.258 1.00 70.05  ? 375 ARG A CD  1 
ATOM   1975 N NE  . ARG A 1 301 ? 121.919 149.213 108.044 1.00 72.19  ? 375 ARG A NE  1 
ATOM   1976 C CZ  . ARG A 1 301 ? 120.743 148.618 108.196 1.00 71.63  ? 375 ARG A CZ  1 
ATOM   1977 N NH1 . ARG A 1 301 ? 120.479 147.454 107.625 1.00 70.83  ? 375 ARG A NH1 1 
ATOM   1978 N NH2 . ARG A 1 301 ? 119.809 149.205 108.938 1.00 70.89  ? 375 ARG A NH2 1 
ATOM   1979 N N   . ASN A 1 302 ? 126.886 151.226 110.485 1.00 60.68  ? 376 ASN A N   1 
ATOM   1980 C CA  . ASN A 1 302 ? 127.311 151.668 111.810 1.00 60.38  ? 376 ASN A CA  1 
ATOM   1981 C C   . ASN A 1 302 ? 128.802 151.442 112.036 1.00 58.60  ? 376 ASN A C   1 
ATOM   1982 O O   . ASN A 1 302 ? 129.482 150.824 111.211 1.00 61.23  ? 376 ASN A O   1 
ATOM   1983 C CB  . ASN A 1 302 ? 126.500 150.962 112.902 1.00 59.93  ? 376 ASN A CB  1 
ATOM   1984 C CG  . ASN A 1 302 ? 125.024 151.295 112.841 1.00 64.77  ? 376 ASN A CG  1 
ATOM   1985 O OD1 . ASN A 1 302 ? 124.191 150.429 112.576 1.00 64.89  ? 376 ASN A OD1 1 
ATOM   1986 N ND2 . ASN A 1 302 ? 124.692 152.557 113.089 1.00 63.84  ? 376 ASN A ND2 1 
ATOM   1987 N N   . THR A 1 303 ? 129.318 151.954 113.148 1.00 46.89  ? 377 THR A N   1 
ATOM   1988 C CA  . THR A 1 303 ? 130.700 151.751 113.547 1.00 43.89  ? 377 THR A CA  1 
ATOM   1989 C C   . THR A 1 303 ? 130.753 150.722 114.672 1.00 45.16  ? 377 THR A C   1 
ATOM   1990 O O   . THR A 1 303 ? 129.727 150.221 115.137 1.00 48.27  ? 377 THR A O   1 
ATOM   1991 C CB  . THR A 1 303 ? 131.336 153.074 113.974 1.00 47.04  ? 377 THR A CB  1 
ATOM   1992 O OG1 . THR A 1 303 ? 130.742 153.515 115.201 1.00 48.30  ? 377 THR A OG1 1 
ATOM   1993 C CG2 . THR A 1 303 ? 131.125 154.134 112.906 1.00 48.13  ? 377 THR A CG2 1 
ATOM   1994 N N   . ALA A 1 304 ? 131.963 150.399 115.120 1.00 43.61  ? 378 ALA A N   1 
ATOM   1995 C CA  . ALA A 1 304 ? 132.120 149.440 116.202 1.00 38.87  ? 378 ALA A CA  1 
ATOM   1996 C C   . ALA A 1 304 ? 132.826 150.100 117.379 1.00 44.46  ? 378 ALA A C   1 
ATOM   1997 O O   . ALA A 1 304 ? 133.406 151.179 117.253 1.00 50.62  ? 378 ALA A O   1 
ATOM   1998 C CB  . ALA A 1 304 ? 132.891 148.197 115.745 1.00 44.15  ? 378 ALA A CB  1 
ATOM   1999 N N   . TRP A 1 305 ? 132.773 149.439 118.533 1.00 40.41  ? 379 TRP A N   1 
ATOM   2000 C CA  . TRP A 1 305 ? 133.347 149.969 119.761 1.00 40.25  ? 379 TRP A CA  1 
ATOM   2001 C C   . TRP A 1 305 ? 134.272 148.929 120.370 1.00 41.82  ? 379 TRP A C   1 
ATOM   2002 O O   . TRP A 1 305 ? 133.885 147.769 120.536 1.00 50.12  ? 379 TRP A O   1 
ATOM   2003 C CB  . TRP A 1 305 ? 132.248 150.357 120.753 1.00 43.88  ? 379 TRP A CB  1 
ATOM   2004 C CG  . TRP A 1 305 ? 131.448 151.541 120.309 1.00 43.25  ? 379 TRP A CG  1 
ATOM   2005 C CD1 . TRP A 1 305 ? 130.302 151.523 119.572 1.00 47.34  ? 379 TRP A CD1 1 
ATOM   2006 C CD2 . TRP A 1 305 ? 131.733 152.918 120.575 1.00 45.24  ? 379 TRP A CD2 1 
ATOM   2007 N NE1 . TRP A 1 305 ? 129.855 152.804 119.360 1.00 49.69  ? 379 TRP A NE1 1 
ATOM   2008 C CE2 . TRP A 1 305 ? 130.716 153.679 119.967 1.00 44.35  ? 379 TRP A CE2 1 
ATOM   2009 C CE3 . TRP A 1 305 ? 132.748 153.582 121.269 1.00 46.52  ? 379 TRP A CE3 1 
ATOM   2010 C CZ2 . TRP A 1 305 ? 130.685 155.069 120.031 1.00 43.06  ? 379 TRP A CZ2 1 
ATOM   2011 C CZ3 . TRP A 1 305 ? 132.716 154.962 121.331 1.00 45.66  ? 379 TRP A CZ3 1 
ATOM   2012 C CH2 . TRP A 1 305 ? 131.692 155.690 120.716 1.00 44.66  ? 379 TRP A CH2 1 
ATOM   2013 N N   . VAL A 1 306 ? 135.486 149.349 120.711 1.00 33.91  ? 380 VAL A N   1 
ATOM   2014 C CA  . VAL A 1 306 ? 136.504 148.470 121.273 1.00 23.84  ? 380 VAL A CA  1 
ATOM   2015 C C   . VAL A 1 306 ? 136.721 148.846 122.733 1.00 34.40  ? 380 VAL A C   1 
ATOM   2016 O O   . VAL A 1 306 ? 136.846 150.030 123.072 1.00 44.20  ? 380 VAL A O   1 
ATOM   2017 C CB  . VAL A 1 306 ? 137.815 148.535 120.465 1.00 31.20  ? 380 VAL A CB  1 
ATOM   2018 C CG1 . VAL A 1 306 ? 138.406 149.938 120.475 1.00 40.91  ? 380 VAL A CG1 1 
ATOM   2019 C CG2 . VAL A 1 306 ? 138.815 147.529 120.999 1.00 28.36  ? 380 VAL A CG2 1 
ATOM   2020 N N   . SER A 1 307 ? 136.730 147.835 123.598 1.00 34.23  ? 381 SER A N   1 
ATOM   2021 C CA  . SER A 1 307 ? 136.924 148.000 125.030 1.00 30.87  ? 381 SER A CA  1 
ATOM   2022 C C   . SER A 1 307 ? 138.046 147.084 125.490 1.00 31.28  ? 381 SER A C   1 
ATOM   2023 O O   . SER A 1 307 ? 138.109 145.917 125.094 1.00 28.80  ? 381 SER A O   1 
ATOM   2024 C CB  . SER A 1 307 ? 135.641 147.689 125.807 1.00 34.36  ? 381 SER A CB  1 
ATOM   2025 O OG  . SER A 1 307 ? 135.889 147.645 127.201 1.00 41.32  ? 381 SER A OG  1 
ATOM   2026 N N   . PHE A 1 308 ? 138.925 147.618 126.331 1.00 37.80  ? 382 PHE A N   1 
ATOM   2027 C CA  . PHE A 1 308 ? 140.117 146.914 126.796 1.00 27.20  ? 382 PHE A CA  1 
ATOM   2028 C C   . PHE A 1 308 ? 139.946 146.597 128.278 1.00 31.09  ? 382 PHE A C   1 
ATOM   2029 O O   . PHE A 1 308 ? 140.082 147.481 129.128 1.00 42.76  ? 382 PHE A O   1 
ATOM   2030 C CB  . PHE A 1 308 ? 141.368 147.751 126.545 1.00 32.39  ? 382 PHE A CB  1 
ATOM   2031 C CG  . PHE A 1 308 ? 141.468 148.289 125.147 1.00 31.59  ? 382 PHE A CG  1 
ATOM   2032 C CD1 . PHE A 1 308 ? 142.095 147.557 124.155 1.00 31.78  ? 382 PHE A CD1 1 
ATOM   2033 C CD2 . PHE A 1 308 ? 140.944 149.529 124.824 1.00 36.18  ? 382 PHE A CD2 1 
ATOM   2034 C CE1 . PHE A 1 308 ? 142.190 148.046 122.869 1.00 31.81  ? 382 PHE A CE1 1 
ATOM   2035 C CE2 . PHE A 1 308 ? 141.037 150.023 123.539 1.00 37.07  ? 382 PHE A CE2 1 
ATOM   2036 C CZ  . PHE A 1 308 ? 141.662 149.280 122.561 1.00 36.40  ? 382 PHE A CZ  1 
ATOM   2037 N N   . ASP A 1 309 ? 139.655 145.330 128.580 1.00 34.99  ? 383 ASP A N   1 
ATOM   2038 C CA  . ASP A 1 309 ? 139.496 144.855 129.957 1.00 33.05  ? 383 ASP A CA  1 
ATOM   2039 C C   . ASP A 1 309 ? 138.395 145.616 130.693 1.00 36.52  ? 383 ASP A C   1 
ATOM   2040 O O   . ASP A 1 309 ? 138.514 145.915 131.882 1.00 40.13  ? 383 ASP A O   1 
ATOM   2041 C CB  . ASP A 1 309 ? 140.815 144.941 130.728 1.00 36.65  ? 383 ASP A CB  1 
ATOM   2042 C CG  . ASP A 1 309 ? 141.606 143.652 130.676 1.00 45.54  ? 383 ASP A CG  1 
ATOM   2043 O OD1 . ASP A 1 309 ? 140.982 142.572 130.654 1.00 49.16  ? 383 ASP A OD1 1 
ATOM   2044 O OD2 . ASP A 1 309 ? 142.853 143.719 130.664 1.00 46.72  ? 383 ASP A OD2 1 
ATOM   2045 N N   . GLY A 1 310 ? 137.310 145.923 129.986 1.00 40.38  ? 384 GLY A N   1 
ATOM   2046 C CA  . GLY A 1 310 ? 136.212 146.657 130.586 1.00 40.20  ? 384 GLY A CA  1 
ATOM   2047 C C   . GLY A 1 310 ? 136.605 148.053 131.021 1.00 39.35  ? 384 GLY A C   1 
ATOM   2048 O O   . GLY A 1 310 ? 136.297 148.476 132.139 1.00 46.87  ? 384 GLY A O   1 
ATOM   2049 N N   . ARG A 1 311 ? 137.285 148.777 130.141 1.00 38.45  ? 385 ARG A N   1 
ATOM   2050 C CA  . ARG A 1 311 ? 137.835 150.090 130.460 1.00 38.68  ? 385 ARG A CA  1 
ATOM   2051 C C   . ARG A 1 311 ? 137.580 150.997 129.262 1.00 43.51  ? 385 ARG A C   1 
ATOM   2052 O O   . ARG A 1 311 ? 136.708 150.717 128.431 1.00 50.42  ? 385 ARG A O   1 
ATOM   2053 C CB  . ARG A 1 311 ? 139.317 149.980 130.844 1.00 44.81  ? 385 ARG A CB  1 
ATOM   2054 C CG  . ARG A 1 311 ? 139.546 149.796 132.334 1.00 44.46  ? 385 ARG A CG  1 
ATOM   2055 C CD  . ARG A 1 311 ? 140.569 148.707 132.610 1.00 46.51  ? 385 ARG A CD  1 
ATOM   2056 N NE  . ARG A 1 311 ? 140.916 148.634 134.024 1.00 50.21  ? 385 ARG A NE  1 
ATOM   2057 C CZ  . ARG A 1 311 ? 140.427 147.736 134.868 1.00 51.42  ? 385 ARG A CZ  1 
ATOM   2058 N NH1 . ARG A 1 311 ? 139.565 146.814 134.474 1.00 46.91  ? 385 ARG A NH1 1 
ATOM   2059 N NH2 . ARG A 1 311 ? 140.812 147.765 136.141 1.00 49.15  ? 385 ARG A NH2 1 
ATOM   2060 N N   . LYS A 1 312 ? 138.323 152.103 129.193 1.00 52.22  ? 386 LYS A N   1 
ATOM   2061 C CA  . LYS A 1 312 ? 138.120 153.171 128.217 1.00 57.44  ? 386 LYS A CA  1 
ATOM   2062 C C   . LYS A 1 312 ? 137.782 152.627 126.836 1.00 53.05  ? 386 LYS A C   1 
ATOM   2063 O O   . LYS A 1 312 ? 138.543 151.847 126.255 1.00 51.42  ? 386 LYS A O   1 
ATOM   2064 C CB  . LYS A 1 312 ? 139.378 154.040 128.140 1.00 55.89  ? 386 LYS A CB  1 
ATOM   2065 C CG  . LYS A 1 312 ? 139.714 154.768 129.430 1.00 56.01  ? 386 LYS A CG  1 
ATOM   2066 C CD  . LYS A 1 312 ? 140.934 155.659 129.256 1.00 55.01  ? 386 LYS A CD  1 
ATOM   2067 C CE  . LYS A 1 312 ? 142.201 154.835 129.094 1.00 55.20  ? 386 LYS A CE  1 
ATOM   2068 N NZ  . LYS A 1 312 ? 142.532 154.075 130.331 1.00 55.53  ? 386 LYS A NZ  1 
ATOM   2069 N N   . ARG A 1 313 ? 136.632 153.044 126.316 1.00 45.59  ? 387 ARG A N   1 
ATOM   2070 C CA  . ARG A 1 313 ? 136.091 152.525 125.069 1.00 45.93  ? 387 ARG A CA  1 
ATOM   2071 C C   . ARG A 1 313 ? 136.401 153.483 123.928 1.00 48.08  ? 387 ARG A C   1 
ATOM   2072 O O   . ARG A 1 313 ? 136.190 154.693 124.051 1.00 54.07  ? 387 ARG A O   1 
ATOM   2073 C CB  . ARG A 1 313 ? 134.581 152.314 125.181 1.00 42.63  ? 387 ARG A CB  1 
ATOM   2074 C CG  . ARG A 1 313 ? 134.174 151.296 126.228 1.00 44.31  ? 387 ARG A CG  1 
ATOM   2075 C CD  . ARG A 1 313 ? 133.105 150.358 125.696 1.00 47.01  ? 387 ARG A CD  1 
ATOM   2076 N NE  . ARG A 1 313 ? 131.975 151.084 125.132 1.00 47.53  ? 387 ARG A NE  1 
ATOM   2077 C CZ  . ARG A 1 313 ? 130.901 150.508 124.609 1.00 50.95  ? 387 ARG A CZ  1 
ATOM   2078 N NH1 . ARG A 1 313 ? 130.777 149.192 124.560 1.00 51.68  ? 387 ARG A NH1 1 
ATOM   2079 N NH2 . ARG A 1 313 ? 129.927 151.272 124.122 1.00 53.29  ? 387 ARG A NH2 1 
ATOM   2080 N N   . GLN A 1 314 ? 136.900 152.937 122.826 1.00 36.93  ? 388 GLN A N   1 
ATOM   2081 C CA  . GLN A 1 314 ? 137.166 153.706 121.622 1.00 36.98  ? 388 GLN A CA  1 
ATOM   2082 C C   . GLN A 1 314 ? 136.209 153.277 120.519 1.00 45.36  ? 388 GLN A C   1 
ATOM   2083 O O   . GLN A 1 314 ? 135.585 152.217 120.588 1.00 50.20  ? 388 GLN A O   1 
ATOM   2084 C CB  . GLN A 1 314 ? 138.616 153.529 121.161 1.00 42.28  ? 388 GLN A CB  1 
ATOM   2085 C CG  . GLN A 1 314 ? 139.643 153.694 122.266 1.00 43.73  ? 388 GLN A CG  1 
ATOM   2086 C CD  . GLN A 1 314 ? 141.064 153.688 121.742 1.00 49.45  ? 388 GLN A CD  1 
ATOM   2087 O OE1 . GLN A 1 314 ? 142.022 153.685 122.514 1.00 49.96  ? 388 GLN A OE1 1 
ATOM   2088 N NE2 . GLN A 1 314 ? 141.208 153.688 120.422 1.00 49.98  ? 388 GLN A NE2 1 
ATOM   2089 N N   . GLU A 1 315 ? 136.095 154.117 119.497 1.00 49.99  ? 389 GLU A N   1 
ATOM   2090 C CA  . GLU A 1 315 ? 135.235 153.850 118.354 1.00 43.51  ? 389 GLU A CA  1 
ATOM   2091 C C   . GLU A 1 315 ? 136.094 153.586 117.127 1.00 46.49  ? 389 GLU A C   1 
ATOM   2092 O O   . GLU A 1 315 ? 136.968 154.392 116.791 1.00 52.04  ? 389 GLU A O   1 
ATOM   2093 C CB  . GLU A 1 315 ? 134.286 155.021 118.093 1.00 45.93  ? 389 GLU A CB  1 
ATOM   2094 C CG  . GLU A 1 315 ? 133.199 154.718 117.077 1.00 48.24  ? 389 GLU A CG  1 
ATOM   2095 C CD  . GLU A 1 315 ? 132.390 155.943 116.705 1.00 50.52  ? 389 GLU A CD  1 
ATOM   2096 O OE1 . GLU A 1 315 ? 132.799 157.063 117.078 1.00 51.15  ? 389 GLU A OE1 1 
ATOM   2097 O OE2 . GLU A 1 315 ? 131.345 155.787 116.039 1.00 53.16  ? 389 GLU A OE2 1 
ATOM   2098 N N   . ILE A 1 316 ? 135.847 152.460 116.463 1.00 46.01  ? 390 ILE A N   1 
ATOM   2099 C CA  . ILE A 1 316 ? 136.552 152.087 115.245 1.00 44.43  ? 390 ILE A CA  1 
ATOM   2100 C C   . ILE A 1 316 ? 135.591 152.208 114.069 1.00 46.73  ? 390 ILE A C   1 
ATOM   2101 O O   . ILE A 1 316 ? 134.453 151.715 114.119 1.00 51.67  ? 390 ILE A O   1 
ATOM   2102 C CB  . ILE A 1 316 ? 137.167 150.677 115.343 1.00 38.90  ? 390 ILE A CB  1 
ATOM   2103 C CG1 . ILE A 1 316 ? 136.093 149.601 115.488 1.00 43.52  ? 390 ILE A CG1 1 
ATOM   2104 C CG2 . ILE A 1 316 ? 138.150 150.607 116.501 1.00 43.17  ? 390 ILE A CG2 1 
ATOM   2105 C CD1 . ILE A 1 316 ? 136.630 148.190 115.414 1.00 48.06  ? 390 ILE A CD1 1 
ATOM   2106 N N   . ARG A 1 317 ? 136.044 152.912 113.035 1.00 51.00  ? 391 ARG A N   1 
ATOM   2107 C CA  . ARG A 1 317 ? 135.324 153.175 111.804 1.00 45.92  ? 391 ARG A CA  1 
ATOM   2108 C C   . ARG A 1 317 ? 135.880 152.289 110.689 1.00 51.47  ? 391 ARG A C   1 
ATOM   2109 O O   . ARG A 1 317 ? 136.662 151.364 110.931 1.00 58.31  ? 391 ARG A O   1 
ATOM   2110 C CB  . ARG A 1 317 ? 135.421 154.663 111.468 1.00 46.99  ? 391 ARG A CB  1 
ATOM   2111 C CG  . ARG A 1 317 ? 134.685 155.555 112.452 1.00 51.03  ? 391 ARG A CG  1 
ATOM   2112 C CD  . ARG A 1 317 ? 134.815 157.022 112.088 1.00 52.21  ? 391 ARG A CD  1 
ATOM   2113 N NE  . ARG A 1 317 ? 134.085 157.873 113.019 1.00 55.19  ? 391 ARG A NE  1 
ATOM   2114 C CZ  . ARG A 1 317 ? 134.606 158.397 114.121 1.00 56.79  ? 391 ARG A CZ  1 
ATOM   2115 N NH1 . ARG A 1 317 ? 135.864 158.174 114.464 1.00 55.36  ? 391 ARG A NH1 1 
ATOM   2116 N NH2 . ARG A 1 317 ? 133.845 159.161 114.899 1.00 54.05  ? 391 ARG A NH2 1 
ATOM   2117 N N   . HIS A 1 318 ? 135.467 152.567 109.449 1.00 53.58  ? 392 HIS A N   1 
ATOM   2118 C CA  . HIS A 1 318 ? 135.888 151.741 108.321 1.00 57.74  ? 392 HIS A CA  1 
ATOM   2119 C C   . HIS A 1 318 ? 137.396 151.790 108.106 1.00 57.45  ? 392 HIS A C   1 
ATOM   2120 O O   . HIS A 1 318 ? 137.995 150.788 107.699 1.00 59.16  ? 392 HIS A O   1 
ATOM   2121 C CB  . HIS A 1 318 ? 135.163 152.181 107.049 1.00 54.95  ? 392 HIS A CB  1 
ATOM   2122 C CG  . HIS A 1 318 ? 133.689 151.927 107.076 1.00 58.12  ? 392 HIS A CG  1 
ATOM   2123 N ND1 . HIS A 1 318 ? 132.786 152.836 107.584 1.00 64.58  ? 392 HIS A ND1 1 
ATOM   2124 C CD2 . HIS A 1 318 ? 132.960 150.866 106.657 1.00 57.07  ? 392 HIS A CD2 1 
ATOM   2125 C CE1 . HIS A 1 318 ? 131.564 152.346 107.478 1.00 63.65  ? 392 HIS A CE1 1 
ATOM   2126 N NE2 . HIS A 1 318 ? 131.642 151.152 106.919 1.00 62.15  ? 392 HIS A NE2 1 
ATOM   2127 N N   . GLY A 1 319 ? 138.023 152.930 108.368 1.00 48.91  ? 393 GLY A N   1 
ATOM   2128 C CA  . GLY A 1 319 ? 139.448 153.085 108.174 1.00 52.45  ? 393 GLY A CA  1 
ATOM   2129 C C   . GLY A 1 319 ? 140.316 152.636 109.328 1.00 57.82  ? 393 GLY A C   1 
ATOM   2130 O O   . GLY A 1 319 ? 141.537 152.820 109.274 1.00 58.17  ? 393 GLY A O   1 
ATOM   2131 N N   . ASP A 1 320 ? 139.733 152.053 110.369 1.00 54.26  ? 394 ASP A N   1 
ATOM   2132 C CA  . ASP A 1 320 ? 140.465 151.662 111.564 1.00 44.48  ? 394 ASP A CA  1 
ATOM   2133 C C   . ASP A 1 320 ? 140.789 150.173 111.531 1.00 44.90  ? 394 ASP A C   1 
ATOM   2134 O O   . ASP A 1 320 ? 140.124 149.383 110.857 1.00 52.52  ? 394 ASP A O   1 
ATOM   2135 C CB  . ASP A 1 320 ? 139.656 151.992 112.820 1.00 48.79  ? 394 ASP A CB  1 
ATOM   2136 C CG  . ASP A 1 320 ? 139.379 153.474 112.958 1.00 54.93  ? 394 ASP A CG  1 
ATOM   2137 O OD1 . ASP A 1 320 ? 140.344 154.260 112.970 1.00 55.57  ? 394 ASP A OD1 1 
ATOM   2138 O OD2 . ASP A 1 320 ? 138.195 153.858 113.034 1.00 57.84  ? 394 ASP A OD2 1 
ATOM   2139 N N   . SER A 1 321 ? 141.830 149.796 112.273 1.00 35.18  ? 395 SER A N   1 
ATOM   2140 C CA  . SER A 1 321 ? 142.232 148.401 112.378 1.00 34.06  ? 395 SER A CA  1 
ATOM   2141 C C   . SER A 1 321 ? 142.701 148.110 113.796 1.00 38.00  ? 395 SER A C   1 
ATOM   2142 O O   . SER A 1 321 ? 143.234 148.987 114.481 1.00 44.60  ? 395 SER A O   1 
ATOM   2143 C CB  . SER A 1 321 ? 143.342 148.054 111.378 1.00 39.43  ? 395 SER A CB  1 
ATOM   2144 O OG  . SER A 1 321 ? 144.544 148.732 111.696 1.00 46.19  ? 395 SER A OG  1 
ATOM   2145 N N   . ILE A 1 322 ? 142.502 146.866 114.230 1.00 30.89  ? 396 ILE A N   1 
ATOM   2146 C CA  . ILE A 1 322 ? 142.927 146.414 115.551 1.00 27.80  ? 396 ILE A CA  1 
ATOM   2147 C C   . ILE A 1 322 ? 143.833 145.204 115.372 1.00 34.15  ? 396 ILE A C   1 
ATOM   2148 O O   . ILE A 1 322 ? 143.407 144.185 114.820 1.00 38.30  ? 396 ILE A O   1 
ATOM   2149 C CB  . ILE A 1 322 ? 141.724 146.072 116.444 1.00 28.65  ? 396 ILE A CB  1 
ATOM   2150 C CG1 . ILE A 1 322 ? 140.909 147.330 116.748 1.00 27.45  ? 396 ILE A CG1 1 
ATOM   2151 C CG2 . ILE A 1 322 ? 142.177 145.393 117.720 1.00 30.17  ? 396 ILE A CG2 1 
ATOM   2152 C CD1 . ILE A 1 322 ? 139.572 147.050 117.387 1.00 34.03  ? 396 ILE A CD1 1 
ATOM   2153 N N   . SER A 1 323 ? 145.070 145.307 115.851 1.00 23.93  ? 397 SER A N   1 
ATOM   2154 C CA  . SER A 1 323 ? 146.054 144.238 115.733 1.00 17.40  ? 397 SER A CA  1 
ATOM   2155 C C   . SER A 1 323 ? 146.310 143.634 117.106 1.00 26.02  ? 397 SER A C   1 
ATOM   2156 O O   . SER A 1 323 ? 146.606 144.358 118.060 1.00 39.82  ? 397 SER A O   1 
ATOM   2157 C CB  . SER A 1 323 ? 147.360 144.760 115.131 1.00 32.15  ? 397 SER A CB  1 
ATOM   2158 O OG  . SER A 1 323 ? 147.161 145.224 113.807 1.00 40.70  ? 397 SER A OG  1 
ATOM   2159 N N   . ILE A 1 324 ? 146.201 142.312 117.201 1.00 24.92  ? 398 ILE A N   1 
ATOM   2160 C CA  . ILE A 1 324 ? 146.258 141.594 118.468 1.00 18.52  ? 398 ILE A CA  1 
ATOM   2161 C C   . ILE A 1 324 ? 147.305 140.494 118.369 1.00 19.41  ? 398 ILE A C   1 
ATOM   2162 O O   . ILE A 1 324 ? 147.294 139.702 117.417 1.00 35.07  ? 398 ILE A O   1 
ATOM   2163 C CB  . ILE A 1 324 ? 144.887 141.000 118.845 1.00 19.50  ? 398 ILE A CB  1 
ATOM   2164 C CG1 . ILE A 1 324 ? 143.859 142.114 119.036 1.00 28.31  ? 398 ILE A CG1 1 
ATOM   2165 C CG2 . ILE A 1 324 ? 144.997 140.156 120.103 1.00 27.92  ? 398 ILE A CG2 1 
ATOM   2166 C CD1 . ILE A 1 324 ? 142.437 141.622 119.112 1.00 30.52  ? 398 ILE A CD1 1 
ATOM   2167 N N   . THR A 1 325 ? 148.206 140.450 119.353 1.00 29.34  ? 399 THR A N   1 
ATOM   2168 C CA  . THR A 1 325 ? 149.221 139.411 119.473 1.00 25.00  ? 399 THR A CA  1 
ATOM   2169 C C   . THR A 1 325 ? 149.355 139.027 120.941 1.00 30.81  ? 399 THR A C   1 
ATOM   2170 O O   . THR A 1 325 ? 148.721 139.618 121.818 1.00 39.02  ? 399 THR A O   1 
ATOM   2171 C CB  . THR A 1 325 ? 150.575 139.875 118.924 1.00 29.42  ? 399 THR A CB  1 
ATOM   2172 O OG1 . THR A 1 325 ? 150.872 141.186 119.419 1.00 34.28  ? 399 THR A OG1 1 
ATOM   2173 C CG2 . THR A 1 325 ? 150.559 139.898 117.415 1.00 34.22  ? 399 THR A CG2 1 
ATOM   2174 N N   . THR A 1 326 ? 150.205 138.040 121.212 1.00 30.04  ? 400 THR A N   1 
ATOM   2175 C CA  . THR A 1 326 ? 150.510 137.642 122.580 1.00 19.49  ? 400 THR A CA  1 
ATOM   2176 C C   . THR A 1 326 ? 151.721 138.421 123.077 1.00 28.60  ? 400 THR A C   1 
ATOM   2177 O O   . THR A 1 326 ? 152.779 138.409 122.440 1.00 39.40  ? 400 THR A O   1 
ATOM   2178 C CB  . THR A 1 326 ? 150.779 136.140 122.671 1.00 25.99  ? 400 THR A CB  1 
ATOM   2179 O OG1 . THR A 1 326 ? 149.668 135.418 122.126 1.00 38.64  ? 400 THR A OG1 1 
ATOM   2180 C CG2 . THR A 1 326 ? 150.983 135.723 124.118 1.00 26.64  ? 400 THR A CG2 1 
ATOM   2181 N N   . SER A 1 327 ? 151.560 139.093 124.213 1.00 29.00  ? 401 SER A N   1 
ATOM   2182 C CA  . SER A 1 327 ? 152.619 139.933 124.747 1.00 27.83  ? 401 SER A CA  1 
ATOM   2183 C C   . SER A 1 327 ? 153.768 139.088 125.289 1.00 34.26  ? 401 SER A C   1 
ATOM   2184 O O   . SER A 1 327 ? 153.607 137.917 125.647 1.00 40.20  ? 401 SER A O   1 
ATOM   2185 C CB  . SER A 1 327 ? 152.078 140.840 125.853 1.00 32.46  ? 401 SER A CB  1 
ATOM   2186 O OG  . SER A 1 327 ? 150.871 141.465 125.458 1.00 38.48  ? 401 SER A OG  1 
ATOM   2187 N N   . THR A 1 328 ? 154.945 139.705 125.345 1.00 33.78  ? 402 THR A N   1 
ATOM   2188 C CA  . THR A 1 328 ? 156.131 139.095 125.926 1.00 37.33  ? 402 THR A CA  1 
ATOM   2189 C C   . THR A 1 328 ? 156.283 139.416 127.407 1.00 42.76  ? 402 THR A C   1 
ATOM   2190 O O   . THR A 1 328 ? 157.298 139.051 128.008 1.00 40.89  ? 402 THR A O   1 
ATOM   2191 C CB  . THR A 1 328 ? 157.384 139.544 125.170 1.00 37.15  ? 402 THR A CB  1 
ATOM   2192 O OG1 . THR A 1 328 ? 157.524 140.966 125.275 1.00 34.14  ? 402 THR A OG1 1 
ATOM   2193 C CG2 . THR A 1 328 ? 157.286 139.159 123.702 1.00 37.84  ? 402 THR A CG2 1 
ATOM   2194 N N   . TYR A 1 329 ? 155.299 140.089 128.005 1.00 41.47  ? 403 TYR A N   1 
ATOM   2195 C CA  . TYR A 1 329 ? 155.345 140.517 129.402 1.00 31.56  ? 403 TYR A CA  1 
ATOM   2196 C C   . TYR A 1 329 ? 154.139 139.937 130.128 1.00 30.68  ? 403 TYR A C   1 
ATOM   2197 O O   . TYR A 1 329 ? 153.097 140.600 130.251 1.00 38.50  ? 403 TYR A O   1 
ATOM   2198 C CB  . TYR A 1 329 ? 155.364 142.040 129.505 1.00 32.52  ? 403 TYR A CB  1 
ATOM   2199 C CG  . TYR A 1 329 ? 156.540 142.692 128.814 1.00 35.58  ? 403 TYR A CG  1 
ATOM   2200 C CD1 . TYR A 1 329 ? 157.842 142.318 129.114 1.00 37.66  ? 403 TYR A CD1 1 
ATOM   2201 C CD2 . TYR A 1 329 ? 156.346 143.680 127.859 1.00 36.59  ? 403 TYR A CD2 1 
ATOM   2202 C CE1 . TYR A 1 329 ? 158.919 142.911 128.484 1.00 37.88  ? 403 TYR A CE1 1 
ATOM   2203 C CE2 . TYR A 1 329 ? 157.416 144.279 127.224 1.00 32.03  ? 403 TYR A CE2 1 
ATOM   2204 C CZ  . TYR A 1 329 ? 158.699 143.891 127.540 1.00 36.44  ? 403 TYR A CZ  1 
ATOM   2205 O OH  . TYR A 1 329 ? 159.769 144.484 126.909 1.00 40.01  ? 403 TYR A OH  1 
ATOM   2206 N N   . PRO A 1 330 ? 154.232 138.707 130.624 1.00 25.30  ? 404 PRO A N   1 
ATOM   2207 C CA  . PRO A 1 330 ? 153.110 138.117 131.360 1.00 23.98  ? 404 PRO A CA  1 
ATOM   2208 C C   . PRO A 1 330 ? 152.981 138.724 132.749 1.00 36.49  ? 404 PRO A C   1 
ATOM   2209 O O   . PRO A 1 330 ? 153.859 139.436 133.239 1.00 44.25  ? 404 PRO A O   1 
ATOM   2210 C CB  . PRO A 1 330 ? 153.476 136.633 131.427 1.00 32.14  ? 404 PRO A CB  1 
ATOM   2211 C CG  . PRO A 1 330 ? 154.961 136.622 131.373 1.00 32.22  ? 404 PRO A CG  1 
ATOM   2212 C CD  . PRO A 1 330 ? 155.352 137.762 130.473 1.00 32.26  ? 404 PRO A CD  1 
ATOM   2213 N N   . LEU A 1 331 ? 151.850 138.425 133.390 1.00 32.09  ? 405 LEU A N   1 
ATOM   2214 C CA  . LEU A 1 331 ? 151.581 138.906 134.737 1.00 17.80  ? 405 LEU A CA  1 
ATOM   2215 C C   . LEU A 1 331 ? 151.835 137.785 135.731 1.00 32.94  ? 405 LEU A C   1 
ATOM   2216 O O   . LEU A 1 331 ? 151.030 136.845 135.805 1.00 38.05  ? 405 LEU A O   1 
ATOM   2217 C CB  . LEU A 1 331 ? 150.142 139.403 134.855 1.00 28.24  ? 405 LEU A CB  1 
ATOM   2218 C CG  . LEU A 1 331 ? 149.701 139.940 136.220 1.00 24.83  ? 405 LEU A CG  1 
ATOM   2219 C CD1 . LEU A 1 331 ? 150.467 141.191 136.601 1.00 33.88  ? 405 LEU A CD1 1 
ATOM   2220 C CD2 . LEU A 1 331 ? 148.208 140.203 136.243 1.00 29.19  ? 405 LEU A CD2 1 
ATOM   2221 N N   . PRO A 1 332 ? 152.917 137.831 136.507 1.00 30.93  ? 406 PRO A N   1 
ATOM   2222 C CA  . PRO A 1 332 ? 153.151 136.796 137.525 1.00 22.11  ? 406 PRO A CA  1 
ATOM   2223 C C   . PRO A 1 332 ? 152.197 136.966 138.698 1.00 29.84  ? 406 PRO A C   1 
ATOM   2224 O O   . PRO A 1 332 ? 152.152 138.023 139.330 1.00 44.63  ? 406 PRO A O   1 
ATOM   2225 C CB  . PRO A 1 332 ? 154.609 137.029 137.938 1.00 26.10  ? 406 PRO A CB  1 
ATOM   2226 C CG  . PRO A 1 332 ? 154.878 138.449 137.585 1.00 26.03  ? 406 PRO A CG  1 
ATOM   2227 C CD  . PRO A 1 332 ? 154.075 138.727 136.357 1.00 30.37  ? 406 PRO A CD  1 
ATOM   2228 N N   . SER A 1 333 ? 151.430 135.917 138.985 1.00 21.15  ? 407 SER A N   1 
ATOM   2229 C CA  . SER A 1 333 ? 150.469 135.915 140.080 1.00 17.64  ? 407 SER A CA  1 
ATOM   2230 C C   . SER A 1 333 ? 150.849 134.817 141.063 1.00 27.01  ? 407 SER A C   1 
ATOM   2231 O O   . SER A 1 333 ? 150.891 133.638 140.696 1.00 38.37  ? 407 SER A O   1 
ATOM   2232 C CB  . SER A 1 333 ? 149.045 135.707 139.564 1.00 18.90  ? 407 SER A CB  1 
ATOM   2233 O OG  . SER A 1 333 ? 148.858 134.380 139.106 1.00 36.01  ? 407 SER A OG  1 
ATOM   2234 N N   . ILE A 1 334 ? 151.124 135.207 142.307 1.00 21.74  ? 408 ILE A N   1 
ATOM   2235 C CA  . ILE A 1 334 ? 151.487 134.240 143.334 1.00 18.26  ? 408 ILE A CA  1 
ATOM   2236 C C   . ILE A 1 334 ? 150.258 133.442 143.744 1.00 31.86  ? 408 ILE A C   1 
ATOM   2237 O O   . ILE A 1 334 ? 149.158 133.991 143.901 1.00 42.41  ? 408 ILE A O   1 
ATOM   2238 C CB  . ILE A 1 334 ? 152.123 134.955 144.539 1.00 22.82  ? 408 ILE A CB  1 
ATOM   2239 C CG1 . ILE A 1 334 ? 153.200 135.931 144.064 1.00 19.58  ? 408 ILE A CG1 1 
ATOM   2240 C CG2 . ILE A 1 334 ? 152.706 133.947 145.512 1.00 31.69  ? 408 ILE A CG2 1 
ATOM   2241 C CD1 . ILE A 1 334 ? 153.624 136.932 145.110 1.00 26.33  ? 408 ILE A CD1 1 
ATOM   2242 N N   . CYS A 1 335 ? 150.439 132.137 143.923 1.00 26.88  ? 409 CYS A N   1 
ATOM   2243 C CA  . CYS A 1 335 ? 149.351 131.223 144.230 1.00 24.40  ? 409 CYS A CA  1 
ATOM   2244 C C   . CYS A 1 335 ? 149.571 130.588 145.597 1.00 33.26  ? 409 CYS A C   1 
ATOM   2245 O O   . CYS A 1 335 ? 150.710 130.408 146.039 1.00 40.11  ? 409 CYS A O   1 
ATOM   2246 C CB  . CYS A 1 335 ? 149.227 130.138 143.156 1.00 32.11  ? 409 CYS A CB  1 
ATOM   2247 S SG  . CYS A 1 335 ? 150.663 129.059 143.025 1.00 50.73  ? 409 CYS A SG  1 
ATOM   2248 N N   . VAL A 1 336 ? 148.465 130.253 146.266 1.00 31.42  ? 410 VAL A N   1 
ATOM   2249 C CA  . VAL A 1 336 ? 148.549 129.770 147.642 1.00 20.72  ? 410 VAL A CA  1 
ATOM   2250 C C   . VAL A 1 336 ? 149.163 128.372 147.695 1.00 27.88  ? 410 VAL A C   1 
ATOM   2251 O O   . VAL A 1 336 ? 150.044 128.101 148.518 1.00 36.19  ? 410 VAL A O   1 
ATOM   2252 C CB  . VAL A 1 336 ? 147.167 129.824 148.322 1.00 21.04  ? 410 VAL A CB  1 
ATOM   2253 C CG1 . VAL A 1 336 ? 146.712 131.263 148.463 1.00 29.90  ? 410 VAL A CG1 1 
ATOM   2254 C CG2 . VAL A 1 336 ? 146.133 129.044 147.535 1.00 29.61  ? 410 VAL A CG2 1 
ATOM   2255 N N   . ARG A 1 337 ? 148.713 127.464 146.827 1.00 28.41  ? 411 ARG A N   1 
ATOM   2256 C CA  . ARG A 1 337 ? 149.255 126.108 146.804 1.00 28.51  ? 411 ARG A CA  1 
ATOM   2257 C C   . ARG A 1 337 ? 149.962 125.789 145.494 1.00 33.97  ? 411 ARG A C   1 
ATOM   2258 O O   . ARG A 1 337 ? 151.156 125.472 145.507 1.00 40.21  ? 411 ARG A O   1 
ATOM   2259 C CB  . ARG A 1 337 ? 148.139 125.089 147.068 1.00 26.83  ? 411 ARG A CB  1 
ATOM   2260 C CG  . ARG A 1 337 ? 147.093 125.543 148.067 1.00 31.50  ? 411 ARG A CG  1 
ATOM   2261 C CD  . ARG A 1 337 ? 146.179 124.394 148.459 1.00 36.01  ? 411 ARG A CD  1 
ATOM   2262 N NE  . ARG A 1 337 ? 145.105 124.190 147.494 1.00 41.99  ? 411 ARG A NE  1 
ATOM   2263 C CZ  . ARG A 1 337 ? 144.012 124.936 147.416 1.00 41.67  ? 411 ARG A CZ  1 
ATOM   2264 N NH1 . ARG A 1 337 ? 143.808 125.952 148.238 1.00 40.42  ? 411 ARG A NH1 1 
ATOM   2265 N NH2 . ARG A 1 337 ? 143.097 124.653 146.493 1.00 39.57  ? 411 ARG A NH2 1 
ATOM   2266 N N   . ASP A 1 338 ? 149.268 125.884 144.368 1.00 35.42  ? 412 ASP A N   1 
ATOM   2267 C CA  . ASP A 1 338 ? 149.806 125.554 143.054 1.00 35.05  ? 412 ASP A CA  1 
ATOM   2268 C C   . ASP A 1 338 ? 148.754 125.919 142.007 1.00 37.43  ? 412 ASP A C   1 
ATOM   2269 O O   . ASP A 1 338 ? 147.576 126.068 142.343 1.00 41.88  ? 412 ASP A O   1 
ATOM   2270 C CB  . ASP A 1 338 ? 150.192 124.066 142.959 1.00 33.09  ? 412 ASP A CB  1 
ATOM   2271 C CG  . ASP A 1 338 ? 150.776 123.697 141.616 1.00 39.65  ? 412 ASP A CG  1 
ATOM   2272 O OD1 . ASP A 1 338 ? 151.863 124.203 141.283 1.00 47.90  ? 412 ASP A OD1 1 
ATOM   2273 O OD2 . ASP A 1 338 ? 150.146 122.898 140.893 1.00 38.03  ? 412 ASP A OD2 1 
ATOM   2274 N N   . PRO A 1 339 ? 149.161 126.089 140.743 1.00 30.43  ? 413 PRO A N   1 
ATOM   2275 C CA  . PRO A 1 339 ? 148.202 126.572 139.733 1.00 32.30  ? 413 PRO A CA  1 
ATOM   2276 C C   . PRO A 1 339 ? 146.958 125.712 139.577 1.00 33.95  ? 413 PRO A C   1 
ATOM   2277 O O   . PRO A 1 339 ? 145.846 126.252 139.520 1.00 43.85  ? 413 PRO A O   1 
ATOM   2278 C CB  . PRO A 1 339 ? 149.032 126.587 138.442 1.00 35.58  ? 413 PRO A CB  1 
ATOM   2279 C CG  . PRO A 1 339 ? 150.441 126.675 138.882 1.00 35.04  ? 413 PRO A CG  1 
ATOM   2280 C CD  . PRO A 1 339 ? 150.541 126.038 140.227 1.00 30.22  ? 413 PRO A CD  1 
ATOM   2281 N N   . VAL A 1 340 ? 147.107 124.387 139.518 1.00 28.74  ? 414 VAL A N   1 
ATOM   2282 C CA  . VAL A 1 340 ? 145.980 123.530 139.156 1.00 28.96  ? 414 VAL A CA  1 
ATOM   2283 C C   . VAL A 1 340 ? 144.926 123.519 140.256 1.00 30.40  ? 414 VAL A C   1 
ATOM   2284 O O   . VAL A 1 340 ? 143.730 123.707 139.994 1.00 38.49  ? 414 VAL A O   1 
ATOM   2285 C CB  . VAL A 1 340 ? 146.470 122.107 138.839 1.00 36.77  ? 414 VAL A CB  1 
ATOM   2286 C CG1 . VAL A 1 340 ? 145.285 121.200 138.569 1.00 37.43  ? 414 VAL A CG1 1 
ATOM   2287 C CG2 . VAL A 1 340 ? 147.417 122.125 137.652 1.00 34.40  ? 414 VAL A CG2 1 
ATOM   2288 N N   . SER A 1 341 ? 145.347 123.285 141.501 1.00 26.66  ? 415 SER A N   1 
ATOM   2289 C CA  . SER A 1 341 ? 144.380 123.189 142.588 1.00 30.63  ? 415 SER A CA  1 
ATOM   2290 C C   . SER A 1 341 ? 143.702 124.527 142.836 1.00 35.83  ? 415 SER A C   1 
ATOM   2291 O O   . SER A 1 341 ? 142.500 124.575 143.114 1.00 46.29  ? 415 SER A O   1 
ATOM   2292 C CB  . SER A 1 341 ? 145.053 122.684 143.863 1.00 35.60  ? 415 SER A CB  1 
ATOM   2293 O OG  . SER A 1 341 ? 145.959 123.643 144.375 1.00 41.78  ? 415 SER A OG  1 
ATOM   2294 N N   . ASP A 1 342 ? 144.454 125.624 142.741 1.00 29.04  ? 416 ASP A N   1 
ATOM   2295 C CA  . ASP A 1 342 ? 143.854 126.943 142.906 1.00 30.93  ? 416 ASP A CA  1 
ATOM   2296 C C   . ASP A 1 342 ? 142.860 127.241 141.791 1.00 34.07  ? 416 ASP A C   1 
ATOM   2297 O O   . ASP A 1 342 ? 141.781 127.790 142.046 1.00 39.83  ? 416 ASP A O   1 
ATOM   2298 C CB  . ASP A 1 342 ? 144.943 128.010 142.961 1.00 33.66  ? 416 ASP A CB  1 
ATOM   2299 C CG  . ASP A 1 342 ? 145.766 127.927 144.226 1.00 44.59  ? 416 ASP A CG  1 
ATOM   2300 O OD1 . ASP A 1 342 ? 145.439 127.088 145.091 1.00 43.92  ? 416 ASP A OD1 1 
ATOM   2301 O OD2 . ASP A 1 342 ? 146.735 128.700 144.359 1.00 42.57  ? 416 ASP A OD2 1 
ATOM   2302 N N   . TRP A 1 343 ? 143.198 126.879 140.550 1.00 34.37  ? 417 TRP A N   1 
ATOM   2303 C CA  . TRP A 1 343 ? 142.270 127.078 139.442 1.00 27.20  ? 417 TRP A CA  1 
ATOM   2304 C C   . TRP A 1 343 ? 140.985 126.288 139.649 1.00 31.64  ? 417 TRP A C   1 
ATOM   2305 O O   . TRP A 1 343 ? 139.882 126.814 139.447 1.00 37.79  ? 417 TRP A O   1 
ATOM   2306 C CB  . TRP A 1 343 ? 142.938 126.679 138.125 1.00 30.76  ? 417 TRP A CB  1 
ATOM   2307 C CG  . TRP A 1 343 ? 142.160 127.068 136.906 1.00 31.07  ? 417 TRP A CG  1 
ATOM   2308 C CD1 . TRP A 1 343 ? 141.864 128.331 136.490 1.00 27.83  ? 417 TRP A CD1 1 
ATOM   2309 C CD2 . TRP A 1 343 ? 141.576 126.182 135.943 1.00 34.68  ? 417 TRP A CD2 1 
ATOM   2310 N NE1 . TRP A 1 343 ? 141.133 128.289 135.328 1.00 32.75  ? 417 TRP A NE1 1 
ATOM   2311 C CE2 . TRP A 1 343 ? 140.943 126.980 134.972 1.00 32.84  ? 417 TRP A CE2 1 
ATOM   2312 C CE3 . TRP A 1 343 ? 141.528 124.791 135.809 1.00 34.46  ? 417 TRP A CE3 1 
ATOM   2313 C CZ2 . TRP A 1 343 ? 140.270 126.435 133.882 1.00 32.68  ? 417 TRP A CZ2 1 
ATOM   2314 C CZ3 . TRP A 1 343 ? 140.861 124.253 134.727 1.00 32.58  ? 417 TRP A CZ3 1 
ATOM   2315 C CH2 . TRP A 1 343 ? 140.240 125.072 133.778 1.00 32.04  ? 417 TRP A CH2 1 
ATOM   2316 N N   . PHE A 1 344 ? 141.103 125.027 140.069 1.00 32.47  ? 418 PHE A N   1 
ATOM   2317 C CA  . PHE A 1 344 ? 139.904 124.214 140.247 1.00 21.98  ? 418 PHE A CA  1 
ATOM   2318 C C   . PHE A 1 344 ? 139.094 124.658 141.459 1.00 25.76  ? 418 PHE A C   1 
ATOM   2319 O O   . PHE A 1 344 ? 137.860 124.594 141.433 1.00 38.13  ? 418 PHE A O   1 
ATOM   2320 C CB  . PHE A 1 344 ? 140.278 122.737 140.350 1.00 20.48  ? 418 PHE A CB  1 
ATOM   2321 C CG  . PHE A 1 344 ? 140.426 122.064 139.016 1.00 30.60  ? 418 PHE A CG  1 
ATOM   2322 C CD1 . PHE A 1 344 ? 139.321 121.551 138.359 1.00 30.50  ? 418 PHE A CD1 1 
ATOM   2323 C CD2 . PHE A 1 344 ? 141.666 121.955 138.413 1.00 33.59  ? 418 PHE A CD2 1 
ATOM   2324 C CE1 . PHE A 1 344 ? 139.453 120.937 137.128 1.00 34.19  ? 418 PHE A CE1 1 
ATOM   2325 C CE2 . PHE A 1 344 ? 141.804 121.342 137.184 1.00 29.77  ? 418 PHE A CE2 1 
ATOM   2326 C CZ  . PHE A 1 344 ? 140.696 120.833 136.541 1.00 32.26  ? 418 PHE A CZ  1 
ATOM   2327 N N   . GLU A 1 345 ? 139.757 125.128 142.518 1.00 23.26  ? 419 GLU A N   1 
ATOM   2328 C CA  . GLU A 1 345 ? 139.034 125.688 143.654 1.00 24.63  ? 419 GLU A CA  1 
ATOM   2329 C C   . GLU A 1 345 ? 138.281 126.949 143.254 1.00 32.91  ? 419 GLU A C   1 
ATOM   2330 O O   . GLU A 1 345 ? 137.138 127.159 143.674 1.00 36.67  ? 419 GLU A O   1 
ATOM   2331 C CB  . GLU A 1 345 ? 140.001 125.976 144.802 1.00 29.55  ? 419 GLU A CB  1 
ATOM   2332 C CG  . GLU A 1 345 ? 139.515 127.037 145.776 1.00 34.43  ? 419 GLU A CG  1 
ATOM   2333 C CD  . GLU A 1 345 ? 140.594 127.481 146.743 1.00 43.99  ? 419 GLU A CD  1 
ATOM   2334 O OE1 . GLU A 1 345 ? 141.498 126.673 147.040 1.00 46.75  ? 419 GLU A OE1 1 
ATOM   2335 O OE2 . GLU A 1 345 ? 140.537 128.640 147.208 1.00 46.73  ? 419 GLU A OE2 1 
ATOM   2336 N N   . SER A 1 346 ? 138.908 127.804 142.442 1.00 31.65  ? 420 SER A N   1 
ATOM   2337 C CA  . SER A 1 346 ? 138.218 128.988 141.945 1.00 21.37  ? 420 SER A CA  1 
ATOM   2338 C C   . SER A 1 346 ? 137.020 128.602 141.089 1.00 26.14  ? 420 SER A C   1 
ATOM   2339 O O   . SER A 1 346 ? 135.957 129.224 141.179 1.00 29.64  ? 420 SER A O   1 
ATOM   2340 C CB  . SER A 1 346 ? 139.185 129.866 141.153 1.00 24.47  ? 420 SER A CB  1 
ATOM   2341 O OG  . SER A 1 346 ? 140.081 130.543 142.017 1.00 31.29  ? 420 SER A OG  1 
ATOM   2342 N N   . LEU A 1 347 ? 137.174 127.575 140.251 1.00 32.50  ? 421 LEU A N   1 
ATOM   2343 C CA  . LEU A 1 347 ? 136.048 127.104 139.450 1.00 30.36  ? 421 LEU A CA  1 
ATOM   2344 C C   . LEU A 1 347 ? 134.916 126.591 140.332 1.00 30.83  ? 421 LEU A C   1 
ATOM   2345 O O   . LEU A 1 347 ? 133.739 126.852 140.061 1.00 40.83  ? 421 LEU A O   1 
ATOM   2346 C CB  . LEU A 1 347 ? 136.511 126.011 138.487 1.00 34.02  ? 421 LEU A CB  1 
ATOM   2347 C CG  . LEU A 1 347 ? 137.018 126.466 137.118 1.00 26.77  ? 421 LEU A CG  1 
ATOM   2348 C CD1 . LEU A 1 347 ? 137.301 125.268 136.231 1.00 31.35  ? 421 LEU A CD1 1 
ATOM   2349 C CD2 . LEU A 1 347 ? 136.020 127.401 136.462 1.00 34.90  ? 421 LEU A CD2 1 
ATOM   2350 N N   . ALA A 1 348 ? 135.255 125.856 141.393 1.00 29.43  ? 422 ALA A N   1 
ATOM   2351 C CA  . ALA A 1 348 ? 134.231 125.285 142.263 1.00 24.89  ? 422 ALA A CA  1 
ATOM   2352 C C   . ALA A 1 348 ? 133.507 126.361 143.065 1.00 26.75  ? 422 ALA A C   1 
ATOM   2353 O O   . ALA A 1 348 ? 132.283 126.300 143.228 1.00 38.92  ? 422 ALA A O   1 
ATOM   2354 C CB  . ALA A 1 348 ? 134.857 124.252 143.198 1.00 31.38  ? 422 ALA A CB  1 
ATOM   2355 N N   . GLN A 1 349 ? 134.239 127.352 143.577 1.00 27.51  ? 423 GLN A N   1 
ATOM   2356 C CA  . GLN A 1 349 ? 133.623 128.351 144.446 1.00 24.76  ? 423 GLN A CA  1 
ATOM   2357 C C   . GLN A 1 349 ? 132.941 129.457 143.649 1.00 29.62  ? 423 GLN A C   1 
ATOM   2358 O O   . GLN A 1 349 ? 131.773 129.775 143.893 1.00 40.48  ? 423 GLN A O   1 
ATOM   2359 C CB  . GLN A 1 349 ? 134.667 128.943 145.396 1.00 28.26  ? 423 GLN A CB  1 
ATOM   2360 C CG  . GLN A 1 349 ? 135.479 127.917 146.165 1.00 34.34  ? 423 GLN A CG  1 
ATOM   2361 C CD  . GLN A 1 349 ? 134.811 127.494 147.457 1.00 38.16  ? 423 GLN A CD  1 
ATOM   2362 O OE1 . GLN A 1 349 ? 134.415 128.332 148.267 1.00 40.59  ? 423 GLN A OE1 1 
ATOM   2363 N NE2 . GLN A 1 349 ? 134.683 126.188 147.657 1.00 36.68  ? 423 GLN A NE2 1 
ATOM   2364 N N   . CYS A 1 350 ? 133.654 130.060 142.696 1.00 31.67  ? 424 CYS A N   1 
ATOM   2365 C CA  . CYS A 1 350 ? 133.118 131.214 141.982 1.00 31.87  ? 424 CYS A CA  1 
ATOM   2366 C C   . CYS A 1 350 ? 132.045 130.801 140.983 1.00 34.54  ? 424 CYS A C   1 
ATOM   2367 O O   . CYS A 1 350 ? 130.893 131.240 141.071 1.00 40.74  ? 424 CYS A O   1 
ATOM   2368 C CB  . CYS A 1 350 ? 134.251 131.960 141.274 1.00 31.20  ? 424 CYS A CB  1 
ATOM   2369 S SG  . CYS A 1 350 ? 135.482 132.681 142.375 1.00 47.60  ? 424 CYS A SG  1 
ATOM   2370 N N   . LEU A 1 351 ? 132.407 129.955 140.022 1.00 34.57  ? 425 LEU A N   1 
ATOM   2371 C CA  . LEU A 1 351 ? 131.519 129.621 138.919 1.00 26.65  ? 425 LEU A CA  1 
ATOM   2372 C C   . LEU A 1 351 ? 130.647 128.402 139.188 1.00 33.36  ? 425 LEU A C   1 
ATOM   2373 O O   . LEU A 1 351 ? 129.784 128.090 138.360 1.00 42.88  ? 425 LEU A O   1 
ATOM   2374 C CB  . LEU A 1 351 ? 132.336 129.392 137.644 1.00 31.34  ? 425 LEU A CB  1 
ATOM   2375 C CG  . LEU A 1 351 ? 132.777 130.656 136.904 1.00 31.27  ? 425 LEU A CG  1 
ATOM   2376 C CD1 . LEU A 1 351 ? 133.771 130.315 135.809 1.00 32.00  ? 425 LEU A CD1 1 
ATOM   2377 C CD2 . LEU A 1 351 ? 131.575 131.391 136.332 1.00 38.19  ? 425 LEU A CD2 1 
ATOM   2378 N N   . HIS A 1 352 ? 130.839 127.721 140.318 1.00 29.14  ? 426 HIS A N   1 
ATOM   2379 C CA  . HIS A 1 352 ? 130.080 126.519 140.663 1.00 24.78  ? 426 HIS A CA  1 
ATOM   2380 C C   . HIS A 1 352 ? 130.145 125.489 139.538 1.00 32.26  ? 426 HIS A C   1 
ATOM   2381 O O   . HIS A 1 352 ? 129.128 124.989 139.051 1.00 40.77  ? 426 HIS A O   1 
ATOM   2382 C CB  . HIS A 1 352 ? 128.633 126.865 141.015 1.00 29.14  ? 426 HIS A CB  1 
ATOM   2383 C CG  . HIS A 1 352 ? 128.505 127.924 142.063 1.00 34.13  ? 426 HIS A CG  1 
ATOM   2384 N ND1 . HIS A 1 352 ? 128.351 127.631 143.401 1.00 34.89  ? 426 HIS A ND1 1 
ATOM   2385 C CD2 . HIS A 1 352 ? 128.512 129.275 141.973 1.00 34.28  ? 426 HIS A CD2 1 
ATOM   2386 C CE1 . HIS A 1 352 ? 128.267 128.755 144.089 1.00 36.17  ? 426 HIS A CE1 1 
ATOM   2387 N NE2 . HIS A 1 352 ? 128.362 129.767 143.246 1.00 37.94  ? 426 HIS A NE2 1 
ATOM   2388 N N   . TRP A 1 353 ? 131.368 125.174 139.126 1.00 27.81  ? 427 TRP A N   1 
ATOM   2389 C CA  . TRP A 1 353 ? 131.598 124.247 138.027 1.00 22.07  ? 427 TRP A CA  1 
ATOM   2390 C C   . TRP A 1 353 ? 131.360 122.819 138.505 1.00 31.82  ? 427 TRP A C   1 
ATOM   2391 O O   . TRP A 1 353 ? 132.087 122.319 139.370 1.00 42.16  ? 427 TRP A O   1 
ATOM   2392 C CB  . TRP A 1 353 ? 133.016 124.423 137.490 1.00 30.90  ? 427 TRP A CB  1 
ATOM   2393 C CG  . TRP A 1 353 ? 133.396 123.483 136.390 1.00 31.26  ? 427 TRP A CG  1 
ATOM   2394 C CD1 . TRP A 1 353 ? 133.020 123.560 135.082 1.00 32.03  ? 427 TRP A CD1 1 
ATOM   2395 C CD2 . TRP A 1 353 ? 134.254 122.342 136.496 1.00 25.37  ? 427 TRP A CD2 1 
ATOM   2396 N NE1 . TRP A 1 353 ? 133.579 122.529 134.369 1.00 29.86  ? 427 TRP A NE1 1 
ATOM   2397 C CE2 . TRP A 1 353 ? 134.342 121.767 135.214 1.00 28.70  ? 427 TRP A CE2 1 
ATOM   2398 C CE3 . TRP A 1 353 ? 134.950 121.747 137.551 1.00 29.08  ? 427 TRP A CE3 1 
ATOM   2399 C CZ2 . TRP A 1 353 ? 135.099 120.629 134.959 1.00 33.70  ? 427 TRP A CZ2 1 
ATOM   2400 C CZ3 . TRP A 1 353 ? 135.700 120.615 137.295 1.00 27.55  ? 427 TRP A CZ3 1 
ATOM   2401 C CH2 . TRP A 1 353 ? 135.768 120.068 136.010 1.00 30.12  ? 427 TRP A CH2 1 
ATOM   2402 N N   . ASN A 1 354 ? 130.337 122.173 137.943 1.00 33.78  ? 428 ASN A N   1 
ATOM   2403 C CA  . ASN A 1 354 ? 129.981 120.788 138.253 1.00 29.68  ? 428 ASN A CA  1 
ATOM   2404 C C   . ASN A 1 354 ? 129.662 120.618 139.740 1.00 37.40  ? 428 ASN A C   1 
ATOM   2405 O O   . ASN A 1 354 ? 130.356 119.921 140.482 1.00 42.05  ? 428 ASN A O   1 
ATOM   2406 C CB  . ASN A 1 354 ? 131.089 119.826 137.812 1.00 30.52  ? 428 ASN A CB  1 
ATOM   2407 C CG  . ASN A 1 354 ? 130.680 118.366 137.917 1.00 36.39  ? 428 ASN A CG  1 
ATOM   2408 O OD1 . ASN A 1 354 ? 131.445 117.464 137.577 1.00 38.94  ? 428 ASN A OD1 1 
ATOM   2409 N ND2 . ASN A 1 354 ? 129.463 118.129 138.392 1.00 42.85  ? 428 ASN A ND2 1 
ATOM   2410 N N   . VAL A 1 355 ? 128.592 121.278 140.167 1.00 41.20  ? 429 VAL A N   1 
ATOM   2411 C CA  . VAL A 1 355 ? 128.075 121.119 141.521 1.00 41.09  ? 429 VAL A CA  1 
ATOM   2412 C C   . VAL A 1 355 ? 126.991 120.049 141.508 1.00 46.57  ? 429 VAL A C   1 
ATOM   2413 O O   . VAL A 1 355 ? 126.114 120.047 140.636 1.00 49.02  ? 429 VAL A O   1 
ATOM   2414 C CB  . VAL A 1 355 ? 127.546 122.454 142.074 1.00 41.67  ? 429 VAL A CB  1 
ATOM   2415 C CG1 . VAL A 1 355 ? 128.691 123.435 142.248 1.00 41.32  ? 429 VAL A CG1 1 
ATOM   2416 C CG2 . VAL A 1 355 ? 126.490 123.045 141.151 1.00 45.07  ? 429 VAL A CG2 1 
ATOM   2417 N N   . ARG A 1 356 ? 127.071 119.123 142.462 1.00 55.02  ? 430 ARG A N   1 
ATOM   2418 C CA  . ARG A 1 356 ? 126.149 117.992 142.554 1.00 56.13  ? 430 ARG A CA  1 
ATOM   2419 C C   . ARG A 1 356 ? 126.109 117.189 141.257 1.00 57.27  ? 430 ARG A C   1 
ATOM   2420 O O   . ARG A 1 356 ? 127.146 116.762 140.747 1.00 54.99  ? 430 ARG A O   1 
ATOM   2421 C CB  . ARG A 1 356 ? 124.741 118.469 142.918 1.00 56.02  ? 430 ARG A CB  1 
ATOM   2422 C CG  . ARG A 1 356 ? 123.738 117.343 143.111 1.00 54.82  ? 430 ARG A CG  1 
ATOM   2423 C CD  . ARG A 1 356 ? 122.375 117.879 143.515 1.00 54.70  ? 430 ARG A CD  1 
ATOM   2424 N NE  . ARG A 1 356 ? 121.413 116.808 143.745 1.00 58.66  ? 430 ARG A NE  1 
ATOM   2425 C CZ  . ARG A 1 356 ? 120.631 116.289 142.808 1.00 59.66  ? 430 ARG A CZ  1 
ATOM   2426 N NH1 . ARG A 1 356 ? 120.670 116.722 141.559 1.00 55.10  ? 430 ARG A NH1 1 
ATOM   2427 N NH2 . ARG A 1 356 ? 119.790 115.312 143.133 1.00 57.75  ? 430 ARG A NH2 1 
ATOM   2428 N N   . THR B 1 7   ? 163.111 112.964 115.223 1.00 77.43  ? 73  THR B N   1 
ATOM   2429 C CA  . THR B 1 7   ? 163.019 111.982 114.150 1.00 78.79  ? 73  THR B CA  1 
ATOM   2430 C C   . THR B 1 7   ? 161.612 111.403 114.055 1.00 78.39  ? 73  THR B C   1 
ATOM   2431 O O   . THR B 1 7   ? 160.966 111.144 115.071 1.00 78.66  ? 73  THR B O   1 
ATOM   2432 C CB  . THR B 1 7   ? 164.024 110.833 114.347 1.00 79.71  ? 73  THR B CB  1 
ATOM   2433 O OG1 . THR B 1 7   ? 163.815 110.227 115.629 1.00 79.95  ? 73  THR B OG1 1 
ATOM   2434 C CG2 . THR B 1 7   ? 165.451 111.353 114.263 1.00 76.70  ? 73  THR B CG2 1 
ATOM   2435 N N   . PHE B 1 8   ? 161.141 111.203 112.825 1.00 70.00  ? 74  PHE B N   1 
ATOM   2436 C CA  . PHE B 1 8   ? 159.812 110.654 112.552 1.00 68.71  ? 74  PHE B CA  1 
ATOM   2437 C C   . PHE B 1 8   ? 159.975 109.595 111.467 1.00 68.47  ? 74  PHE B C   1 
ATOM   2438 O O   . PHE B 1 8   ? 159.930 109.903 110.273 1.00 71.82  ? 74  PHE B O   1 
ATOM   2439 C CB  . PHE B 1 8   ? 158.839 111.752 112.137 1.00 68.51  ? 74  PHE B CB  1 
ATOM   2440 C CG  . PHE B 1 8   ? 158.722 112.864 113.138 1.00 71.03  ? 74  PHE B CG  1 
ATOM   2441 C CD1 . PHE B 1 8   ? 157.905 112.733 114.247 1.00 69.83  ? 74  PHE B CD1 1 
ATOM   2442 C CD2 . PHE B 1 8   ? 159.437 114.039 112.973 1.00 69.96  ? 74  PHE B CD2 1 
ATOM   2443 C CE1 . PHE B 1 8   ? 157.799 113.754 115.172 1.00 69.53  ? 74  PHE B CE1 1 
ATOM   2444 C CE2 . PHE B 1 8   ? 159.335 115.063 113.894 1.00 70.71  ? 74  PHE B CE2 1 
ATOM   2445 C CZ  . PHE B 1 8   ? 158.516 114.920 114.995 1.00 70.64  ? 74  PHE B CZ  1 
ATOM   2446 N N   . GLY B 1 9   ? 160.161 108.347 111.884 1.00 65.98  ? 75  GLY B N   1 
ATOM   2447 C CA  . GLY B 1 9   ? 160.420 107.269 110.962 1.00 67.37  ? 75  GLY B CA  1 
ATOM   2448 C C   . GLY B 1 9   ? 161.904 107.031 110.775 1.00 69.69  ? 75  GLY B C   1 
ATOM   2449 O O   . GLY B 1 9   ? 162.747 107.759 111.309 1.00 67.94  ? 75  GLY B O   1 
ATOM   2450 N N   . PRO B 1 10  ? 162.251 105.988 110.017 1.00 70.27  ? 76  PRO B N   1 
ATOM   2451 C CA  . PRO B 1 10  ? 163.675 105.675 109.809 1.00 69.21  ? 76  PRO B CA  1 
ATOM   2452 C C   . PRO B 1 10  ? 164.467 106.795 109.159 1.00 71.35  ? 76  PRO B C   1 
ATOM   2453 O O   . PRO B 1 10  ? 165.646 106.974 109.487 1.00 69.97  ? 76  PRO B O   1 
ATOM   2454 C CB  . PRO B 1 10  ? 163.627 104.431 108.910 1.00 67.52  ? 76  PRO B CB  1 
ATOM   2455 C CG  . PRO B 1 10  ? 162.298 103.821 109.179 1.00 65.72  ? 76  PRO B CG  1 
ATOM   2456 C CD  . PRO B 1 10  ? 161.367 104.965 109.436 1.00 65.98  ? 76  PRO B CD  1 
ATOM   2457 N N   . LYS B 1 11  ? 163.864 107.555 108.250 1.00 71.81  ? 77  LYS B N   1 
ATOM   2458 C CA  . LYS B 1 11  ? 164.596 108.556 107.482 1.00 70.89  ? 77  LYS B CA  1 
ATOM   2459 C C   . LYS B 1 11  ? 164.023 109.958 107.598 1.00 70.92  ? 77  LYS B C   1 
ATOM   2460 O O   . LYS B 1 11  ? 164.788 110.926 107.633 1.00 71.51  ? 77  LYS B O   1 
ATOM   2461 C CB  . LYS B 1 11  ? 164.642 108.148 106.002 1.00 70.20  ? 77  LYS B CB  1 
ATOM   2462 C CG  . LYS B 1 11  ? 165.444 106.884 105.734 1.00 70.47  ? 77  LYS B CG  1 
ATOM   2463 C CD  . LYS B 1 11  ? 165.465 106.544 104.254 1.00 70.82  ? 77  LYS B CD  1 
ATOM   2464 C CE  . LYS B 1 11  ? 166.339 105.331 103.979 1.00 69.78  ? 77  LYS B CE  1 
ATOM   2465 N NZ  . LYS B 1 11  ? 165.766 104.090 104.570 1.00 69.89  ? 77  LYS B NZ  1 
ATOM   2466 N N   . ALA B 1 12  ? 162.702 110.100 107.653 1.00 71.16  ? 78  ALA B N   1 
ATOM   2467 C CA  . ALA B 1 12  ? 162.094 111.423 107.679 1.00 71.32  ? 78  ALA B CA  1 
ATOM   2468 C C   . ALA B 1 12  ? 162.386 112.133 108.996 1.00 74.35  ? 78  ALA B C   1 
ATOM   2469 O O   . ALA B 1 12  ? 162.443 111.509 110.059 1.00 74.80  ? 78  ALA B O   1 
ATOM   2470 C CB  . ALA B 1 12  ? 160.586 111.320 107.461 1.00 71.06  ? 78  ALA B CB  1 
ATOM   2471 N N   . THR B 1 13  ? 162.568 113.448 108.917 1.00 74.12  ? 79  THR B N   1 
ATOM   2472 C CA  . THR B 1 13  ? 162.867 114.260 110.089 1.00 75.04  ? 79  THR B CA  1 
ATOM   2473 C C   . THR B 1 13  ? 162.457 115.697 109.800 1.00 76.12  ? 79  THR B C   1 
ATOM   2474 O O   . THR B 1 13  ? 162.206 116.076 108.654 1.00 76.75  ? 79  THR B O   1 
ATOM   2475 C CB  . THR B 1 13  ? 164.360 114.181 110.456 1.00 75.91  ? 79  THR B CB  1 
ATOM   2476 O OG1 . THR B 1 13  ? 164.578 114.814 111.722 1.00 74.46  ? 79  THR B OG1 1 
ATOM   2477 C CG2 . THR B 1 13  ? 165.191 115.020 109.497 1.00 73.39  ? 79  THR B CG2 1 
ATOM   2478 N N   . VAL B 1 14  ? 162.386 116.494 110.861 1.00 83.60  ? 80  VAL B N   1 
ATOM   2479 C CA  . VAL B 1 14  ? 162.038 117.903 110.733 1.00 83.98  ? 80  VAL B CA  1 
ATOM   2480 C C   . VAL B 1 14  ? 163.251 118.774 111.035 1.00 81.99  ? 80  VAL B C   1 
ATOM   2481 O O   . VAL B 1 14  ? 164.254 118.297 111.566 1.00 82.26  ? 80  VAL B O   1 
ATOM   2482 C CB  . VAL B 1 14  ? 160.862 118.274 111.651 1.00 82.28  ? 80  VAL B CB  1 
ATOM   2483 C CG1 . VAL B 1 14  ? 159.611 117.512 111.244 1.00 79.91  ? 80  VAL B CG1 1 
ATOM   2484 C CG2 . VAL B 1 14  ? 161.216 118.000 113.104 1.00 81.31  ? 80  VAL B CG2 1 
ATOM   2485 N N   . VAL B 1 22  ? 157.029 124.498 110.150 1.00 55.71  ? 96  VAL B N   1 
ATOM   2486 C CA  . VAL B 1 22  ? 157.629 123.180 110.313 1.00 58.41  ? 96  VAL B CA  1 
ATOM   2487 C C   . VAL B 1 22  ? 157.741 122.485 108.962 1.00 59.97  ? 96  VAL B C   1 
ATOM   2488 O O   . VAL B 1 22  ? 156.740 122.050 108.392 1.00 58.49  ? 96  VAL B O   1 
ATOM   2489 C CB  . VAL B 1 22  ? 156.825 122.321 111.304 1.00 60.34  ? 96  VAL B CB  1 
ATOM   2490 C CG1 . VAL B 1 22  ? 157.434 120.933 111.420 1.00 59.89  ? 96  VAL B CG1 1 
ATOM   2491 C CG2 . VAL B 1 22  ? 156.764 122.999 112.664 1.00 59.32  ? 96  VAL B CG2 1 
ATOM   2492 N N   . ARG B 1 23  ? 158.963 122.384 108.453 1.00 69.71  ? 97  ARG B N   1 
ATOM   2493 C CA  . ARG B 1 23  ? 159.231 121.765 107.165 1.00 68.39  ? 97  ARG B CA  1 
ATOM   2494 C C   . ARG B 1 23  ? 159.658 120.314 107.346 1.00 69.78  ? 97  ARG B C   1 
ATOM   2495 O O   . ARG B 1 23  ? 160.035 119.880 108.438 1.00 71.54  ? 97  ARG B O   1 
ATOM   2496 C CB  . ARG B 1 23  ? 160.311 122.537 106.399 1.00 66.95  ? 97  ARG B CB  1 
ATOM   2497 C CG  . ARG B 1 23  ? 159.807 123.777 105.670 1.00 67.57  ? 97  ARG B CG  1 
ATOM   2498 C CD  . ARG B 1 23  ? 159.564 124.936 106.624 1.00 71.13  ? 97  ARG B CD  1 
ATOM   2499 N NE  . ARG B 1 23  ? 159.143 126.143 105.922 1.00 71.89  ? 97  ARG B NE  1 
ATOM   2500 C CZ  . ARG B 1 23  ? 159.974 127.050 105.427 1.00 72.71  ? 97  ARG B CZ  1 
ATOM   2501 N NH1 . ARG B 1 23  ? 161.286 126.920 105.540 1.00 72.58  ? 97  ARG B NH1 1 
ATOM   2502 N NH2 . ARG B 1 23  ? 159.477 128.114 104.804 1.00 71.62  ? 97  ARG B NH2 1 
ATOM   2503 N N   . LEU B 1 24  ? 159.596 119.564 106.251 1.00 63.01  ? 98  LEU B N   1 
ATOM   2504 C CA  . LEU B 1 24  ? 159.923 118.145 106.239 1.00 62.68  ? 98  LEU B CA  1 
ATOM   2505 C C   . LEU B 1 24  ? 161.206 117.926 105.449 1.00 63.25  ? 98  LEU B C   1 
ATOM   2506 O O   . LEU B 1 24  ? 161.303 118.338 104.288 1.00 65.50  ? 98  LEU B O   1 
ATOM   2507 C CB  . LEU B 1 24  ? 158.776 117.331 105.637 1.00 60.01  ? 98  LEU B CB  1 
ATOM   2508 C CG  . LEU B 1 24  ? 159.092 115.926 105.125 1.00 60.71  ? 98  LEU B CG  1 
ATOM   2509 C CD1 . LEU B 1 24  ? 159.360 114.979 106.283 1.00 61.75  ? 98  LEU B CD1 1 
ATOM   2510 C CD2 . LEU B 1 24  ? 157.950 115.414 104.262 1.00 60.46  ? 98  LEU B CD2 1 
ATOM   2511 N N   . THR B 1 25  ? 162.183 117.278 106.079 1.00 62.09  ? 99  THR B N   1 
ATOM   2512 C CA  . THR B 1 25  ? 163.471 116.986 105.464 1.00 59.95  ? 99  THR B CA  1 
ATOM   2513 C C   . THR B 1 25  ? 163.708 115.484 105.500 1.00 61.65  ? 99  THR B C   1 
ATOM   2514 O O   . THR B 1 25  ? 163.544 114.851 106.548 1.00 66.37  ? 99  THR B O   1 
ATOM   2515 C CB  . THR B 1 25  ? 164.606 117.723 106.181 1.00 65.29  ? 99  THR B CB  1 
ATOM   2516 O OG1 . THR B 1 25  ? 164.409 119.137 106.061 1.00 65.47  ? 99  THR B OG1 1 
ATOM   2517 C CG2 . THR B 1 25  ? 165.952 117.353 105.576 1.00 64.50  ? 99  THR B CG2 1 
ATOM   2518 N N   . TRP B 1 26  ? 164.095 114.917 104.358 1.00 57.07  ? 100 TRP B N   1 
ATOM   2519 C CA  . TRP B 1 26  ? 164.235 113.472 104.238 1.00 58.25  ? 100 TRP B CA  1 
ATOM   2520 C C   . TRP B 1 26  ? 165.616 112.964 104.623 1.00 58.00  ? 100 TRP B C   1 
ATOM   2521 O O   . TRP B 1 26  ? 165.746 111.792 104.997 1.00 61.20  ? 100 TRP B O   1 
ATOM   2522 C CB  . TRP B 1 26  ? 163.923 113.029 102.806 1.00 58.64  ? 100 TRP B CB  1 
ATOM   2523 C CG  . TRP B 1 26  ? 162.493 113.213 102.418 1.00 55.89  ? 100 TRP B CG  1 
ATOM   2524 C CD1 . TRP B 1 26  ? 161.992 114.139 101.552 1.00 55.91  ? 100 TRP B CD1 1 
ATOM   2525 C CD2 . TRP B 1 26  ? 161.375 112.448 102.880 1.00 49.01  ? 100 TRP B CD2 1 
ATOM   2526 N NE1 . TRP B 1 26  ? 160.630 114.000 101.448 1.00 57.50  ? 100 TRP B NE1 1 
ATOM   2527 C CE2 . TRP B 1 26  ? 160.227 112.968 102.254 1.00 53.84  ? 100 TRP B CE2 1 
ATOM   2528 C CE3 . TRP B 1 26  ? 161.233 111.375 103.764 1.00 53.18  ? 100 TRP B CE3 1 
ATOM   2529 C CZ2 . TRP B 1 26  ? 158.955 112.452 102.482 1.00 57.23  ? 100 TRP B CZ2 1 
ATOM   2530 C CZ3 . TRP B 1 26  ? 159.970 110.864 103.988 1.00 56.13  ? 100 TRP B CZ3 1 
ATOM   2531 C CH2 . TRP B 1 26  ? 158.848 111.404 103.351 1.00 57.57  ? 100 TRP B CH2 1 
ATOM   2532 N N   . ASN B 1 27  ? 166.646 113.808 104.523 1.00 68.82  ? 101 ASN B N   1 
ATOM   2533 C CA  . ASN B 1 27  ? 168.034 113.407 104.745 1.00 72.77  ? 101 ASN B CA  1 
ATOM   2534 C C   . ASN B 1 27  ? 168.438 112.341 103.732 1.00 70.18  ? 101 ASN B C   1 
ATOM   2535 O O   . ASN B 1 27  ? 169.283 112.586 102.866 1.00 68.29  ? 101 ASN B O   1 
ATOM   2536 C CB  . ASN B 1 27  ? 168.245 112.910 106.180 1.00 71.09  ? 101 ASN B CB  1 
ATOM   2537 C CG  . ASN B 1 27  ? 169.620 112.304 106.395 1.00 71.82  ? 101 ASN B CG  1 
ATOM   2538 O OD1 . ASN B 1 27  ? 169.853 111.135 106.086 1.00 72.56  ? 101 ASN B OD1 1 
ATOM   2539 N ND2 . ASN B 1 27  ? 170.540 113.100 106.929 1.00 69.62  ? 101 ASN B ND2 1 
ATOM   2540 N N   . LYS B 1 28  ? 167.838 111.159 103.833 1.00 68.49  ? 102 LYS B N   1 
ATOM   2541 C CA  . LYS B 1 28  ? 167.986 110.109 102.837 1.00 67.72  ? 102 LYS B CA  1 
ATOM   2542 C C   . LYS B 1 28  ? 166.716 110.030 102.002 1.00 67.52  ? 102 LYS B C   1 
ATOM   2543 O O   . LYS B 1 28  ? 165.609 110.194 102.524 1.00 68.64  ? 102 LYS B O   1 
ATOM   2544 C CB  . LYS B 1 28  ? 168.280 108.762 103.499 1.00 68.43  ? 102 LYS B CB  1 
ATOM   2545 C CG  . LYS B 1 28  ? 169.642 108.684 104.171 1.00 69.85  ? 102 LYS B CG  1 
ATOM   2546 C CD  . LYS B 1 28  ? 169.858 107.331 104.827 1.00 70.79  ? 102 LYS B CD  1 
ATOM   2547 C CE  . LYS B 1 28  ? 171.229 107.244 105.478 1.00 70.27  ? 102 LYS B CE  1 
ATOM   2548 N NZ  . LYS B 1 28  ? 171.445 105.932 106.146 1.00 68.92  ? 102 LYS B NZ  1 
ATOM   2549 N N   . SER B 1 29  ? 166.881 109.789 100.707 1.00 59.08  ? 103 SER B N   1 
ATOM   2550 C CA  . SER B 1 29  ? 165.741 109.773 99.801  1.00 60.81  ? 103 SER B CA  1 
ATOM   2551 C C   . SER B 1 29  ? 164.781 108.651 100.186 1.00 62.02  ? 103 SER B C   1 
ATOM   2552 O O   . SER B 1 29  ? 165.220 107.512 100.398 1.00 64.52  ? 103 SER B O   1 
ATOM   2553 C CB  . SER B 1 29  ? 166.207 109.596 98.356  1.00 60.19  ? 103 SER B CB  1 
ATOM   2554 O OG  . SER B 1 29  ? 165.110 109.627 97.460  1.00 59.70  ? 103 SER B OG  1 
ATOM   2555 N N   . PRO B 1 30  ? 163.483 108.928 100.302 1.00 50.47  ? 104 PRO B N   1 
ATOM   2556 C CA  . PRO B 1 30  ? 162.537 107.876 100.691 1.00 47.02  ? 104 PRO B CA  1 
ATOM   2557 C C   . PRO B 1 30  ? 162.487 106.759 99.660  1.00 45.96  ? 104 PRO B C   1 
ATOM   2558 O O   . PRO B 1 30  ? 162.557 106.995 98.453  1.00 50.20  ? 104 PRO B O   1 
ATOM   2559 C CB  . PRO B 1 30  ? 161.201 108.620 100.784 1.00 46.81  ? 104 PRO B CB  1 
ATOM   2560 C CG  . PRO B 1 30  ? 161.373 109.809 99.898  1.00 47.31  ? 104 PRO B CG  1 
ATOM   2561 C CD  . PRO B 1 30  ? 162.808 110.212 100.053 1.00 49.01  ? 104 PRO B CD  1 
ATOM   2562 N N   . LYS B 1 31  ? 162.360 105.528 100.154 1.00 48.30  ? 105 LYS B N   1 
ATOM   2563 C CA  . LYS B 1 31  ? 162.293 104.351 99.299  1.00 50.31  ? 105 LYS B CA  1 
ATOM   2564 C C   . LYS B 1 31  ? 161.176 103.386 99.657  1.00 50.87  ? 105 LYS B C   1 
ATOM   2565 O O   . LYS B 1 31  ? 160.799 102.574 98.804  1.00 57.16  ? 105 LYS B O   1 
ATOM   2566 C CB  . LYS B 1 31  ? 163.631 103.611 99.336  1.00 55.73  ? 105 LYS B CB  1 
ATOM   2567 C CG  . LYS B 1 31  ? 164.789 104.390 98.733  1.00 56.04  ? 105 LYS B CG  1 
ATOM   2568 C CD  . LYS B 1 31  ? 166.089 103.608 98.824  1.00 54.00  ? 105 LYS B CD  1 
ATOM   2569 C CE  . LYS B 1 31  ? 167.242 104.377 98.201  1.00 54.60  ? 105 LYS B CE  1 
ATOM   2570 N NZ  . LYS B 1 31  ? 168.527 103.633 98.305  1.00 54.75  ? 105 LYS B NZ  1 
ATOM   2571 N N   . SER B 1 32  ? 160.644 103.430 100.875 1.00 41.82  ? 106 SER B N   1 
ATOM   2572 C CA  . SER B 1 32  ? 159.558 102.557 101.298 1.00 38.17  ? 106 SER B CA  1 
ATOM   2573 C C   . SER B 1 32  ? 158.350 103.406 101.661 1.00 44.13  ? 106 SER B C   1 
ATOM   2574 O O   . SER B 1 32  ? 158.461 104.340 102.462 1.00 49.30  ? 106 SER B O   1 
ATOM   2575 C CB  . SER B 1 32  ? 159.977 101.691 102.487 1.00 44.49  ? 106 SER B CB  1 
ATOM   2576 O OG  . SER B 1 32  ? 161.026 100.808 102.131 1.00 50.08  ? 106 SER B OG  1 
ATOM   2577 N N   . VAL B 1 33  ? 157.201 103.078 101.077 1.00 34.09  ? 107 VAL B N   1 
ATOM   2578 C CA  . VAL B 1 33  ? 155.961 103.808 101.306 1.00 27.14  ? 107 VAL B CA  1 
ATOM   2579 C C   . VAL B 1 33  ? 154.852 102.805 101.589 1.00 35.22  ? 107 VAL B C   1 
ATOM   2580 O O   . VAL B 1 33  ? 154.802 101.729 100.982 1.00 44.86  ? 107 VAL B O   1 
ATOM   2581 C CB  . VAL B 1 33  ? 155.605 104.714 100.106 1.00 28.93  ? 107 VAL B CB  1 
ATOM   2582 C CG1 . VAL B 1 33  ? 155.382 103.889 98.857  1.00 34.70  ? 107 VAL B CG1 1 
ATOM   2583 C CG2 . VAL B 1 33  ? 154.381 105.561 100.413 1.00 38.98  ? 107 VAL B CG2 1 
ATOM   2584 N N   . LEU B 1 34  ? 153.980 103.144 102.533 1.00 33.80  ? 108 LEU B N   1 
ATOM   2585 C CA  . LEU B 1 34  ? 152.856 102.300 102.910 1.00 24.37  ? 108 LEU B CA  1 
ATOM   2586 C C   . LEU B 1 34  ? 151.560 102.958 102.463 1.00 32.49  ? 108 LEU B C   1 
ATOM   2587 O O   . LEU B 1 34  ? 151.311 104.126 102.780 1.00 41.86  ? 108 LEU B O   1 
ATOM   2588 C CB  . LEU B 1 34  ? 152.834 102.060 104.421 1.00 31.16  ? 108 LEU B CB  1 
ATOM   2589 C CG  . LEU B 1 34  ? 151.563 101.430 104.992 1.00 34.56  ? 108 LEU B CG  1 
ATOM   2590 C CD1 . LEU B 1 34  ? 151.370 100.020 104.460 1.00 38.29  ? 108 LEU B CD1 1 
ATOM   2591 C CD2 . LEU B 1 34  ? 151.599 101.432 106.509 1.00 36.50  ? 108 LEU B CD2 1 
ATOM   2592 N N   . VAL B 1 35  ? 150.743 102.212 101.726 1.00 33.38  ? 109 VAL B N   1 
ATOM   2593 C CA  . VAL B 1 35  ? 149.439 102.675 101.268 1.00 22.94  ? 109 VAL B CA  1 
ATOM   2594 C C   . VAL B 1 35  ? 148.367 101.932 102.050 1.00 27.66  ? 109 VAL B C   1 
ATOM   2595 O O   . VAL B 1 35  ? 148.398 100.699 102.145 1.00 40.11  ? 109 VAL B O   1 
ATOM   2596 C CB  . VAL B 1 35  ? 149.268 102.480 99.751  1.00 21.90  ? 109 VAL B CB  1 
ATOM   2597 C CG1 . VAL B 1 35  ? 150.101 103.498 98.996  1.00 28.40  ? 109 VAL B CG1 1 
ATOM   2598 C CG2 . VAL B 1 35  ? 149.671 101.076 99.342  1.00 35.67  ? 109 VAL B CG2 1 
ATOM   2599 N N   . ILE B 1 36  ? 147.432 102.681 102.627 1.00 31.73  ? 110 ILE B N   1 
ATOM   2600 C CA  . ILE B 1 36  ? 146.363 102.123 103.445 1.00 29.29  ? 110 ILE B CA  1 
ATOM   2601 C C   . ILE B 1 36  ? 145.039 102.393 102.747 1.00 32.90  ? 110 ILE B C   1 
ATOM   2602 O O   . ILE B 1 36  ? 144.727 103.542 102.416 1.00 39.06  ? 110 ILE B O   1 
ATOM   2603 C CB  . ILE B 1 36  ? 146.364 102.713 104.867 1.00 31.70  ? 110 ILE B CB  1 
ATOM   2604 C CG1 . ILE B 1 36  ? 147.662 102.352 105.590 1.00 31.36  ? 110 ILE B CG1 1 
ATOM   2605 C CG2 . ILE B 1 36  ? 145.174 102.195 105.653 1.00 36.89  ? 110 ILE B CG2 1 
ATOM   2606 C CD1 . ILE B 1 36  ? 147.864 103.098 106.889 1.00 38.91  ? 110 ILE B CD1 1 
ATOM   2607 N N   . LYS B 1 37  ? 144.266 101.335 102.527 1.00 40.59  ? 111 LYS B N   1 
ATOM   2608 C CA  . LYS B 1 37  ? 142.989 101.415 101.837 1.00 45.79  ? 111 LYS B CA  1 
ATOM   2609 C C   . LYS B 1 37  ? 141.847 101.249 102.833 1.00 50.14  ? 111 LYS B C   1 
ATOM   2610 O O   . LYS B 1 37  ? 141.956 100.509 103.813 1.00 52.38  ? 111 LYS B O   1 
ATOM   2611 C CB  . LYS B 1 37  ? 142.905 100.344 100.746 1.00 47.87  ? 111 LYS B CB  1 
ATOM   2612 C CG  . LYS B 1 37  ? 141.646 100.388 99.898  1.00 47.64  ? 111 LYS B CG  1 
ATOM   2613 C CD  . LYS B 1 37  ? 141.687 99.323  98.816  1.00 46.68  ? 111 LYS B CD  1 
ATOM   2614 C CE  . LYS B 1 37  ? 140.477 99.416  97.905  1.00 48.88  ? 111 LYS B CE  1 
ATOM   2615 N NZ  . LYS B 1 37  ? 139.222 99.061  98.621  1.00 51.49  ? 111 LYS B NZ  1 
ATOM   2616 N N   . LYS B 1 38  ? 140.742 101.950 102.571 1.00 52.79  ? 112 LYS B N   1 
ATOM   2617 C CA  . LYS B 1 38  ? 139.591 101.959 103.475 1.00 54.02  ? 112 LYS B CA  1 
ATOM   2618 C C   . LYS B 1 38  ? 138.782 100.666 103.322 1.00 60.84  ? 112 LYS B C   1 
ATOM   2619 O O   . LYS B 1 38  ? 137.622 100.655 102.910 1.00 61.59  ? 112 LYS B O   1 
ATOM   2620 C CB  . LYS B 1 38  ? 138.740 103.197 103.218 1.00 54.96  ? 112 LYS B CB  1 
ATOM   2621 C CG  . LYS B 1 38  ? 137.552 103.381 104.155 1.00 54.75  ? 112 LYS B CG  1 
ATOM   2622 C CD  . LYS B 1 38  ? 136.806 104.668 103.845 1.00 56.75  ? 112 LYS B CD  1 
ATOM   2623 C CE  . LYS B 1 38  ? 135.676 104.905 104.833 1.00 59.65  ? 112 LYS B CE  1 
ATOM   2624 N NZ  . LYS B 1 38  ? 134.591 103.896 104.685 1.00 59.18  ? 112 LYS B NZ  1 
ATOM   2625 N N   . MET B 1 39  ? 139.442 99.555  103.658 1.00 68.92  ? 113 MET B N   1 
ATOM   2626 C CA  . MET B 1 39  ? 138.834 98.228  103.678 1.00 67.19  ? 113 MET B CA  1 
ATOM   2627 C C   . MET B 1 39  ? 138.069 97.921  102.396 1.00 68.68  ? 113 MET B C   1 
ATOM   2628 O O   . MET B 1 39  ? 138.639 97.954  101.300 1.00 68.03  ? 113 MET B O   1 
ATOM   2629 C CB  . MET B 1 39  ? 137.908 98.091  104.889 1.00 68.03  ? 113 MET B CB  1 
ATOM   2630 C CG  . MET B 1 39  ? 138.586 97.501  106.116 1.00 69.25  ? 113 MET B CG  1 
ATOM   2631 S SD  . MET B 1 39  ? 137.458 97.284  107.506 1.00 84.52  ? 113 MET B SD  1 
ATOM   2632 C CE  . MET B 1 39  ? 136.795 95.659  107.152 1.00 70.35  ? 113 MET B CE  1 
ATOM   2633 N N   . ARG B 1 40  ? 136.778 97.622  102.525 1.00 66.68  ? 114 ARG B N   1 
ATOM   2634 C CA  . ARG B 1 40  ? 135.930 97.290  101.382 1.00 66.67  ? 114 ARG B CA  1 
ATOM   2635 C C   . ARG B 1 40  ? 135.230 98.558  100.911 1.00 63.99  ? 114 ARG B C   1 
ATOM   2636 O O   . ARG B 1 40  ? 134.197 98.953  101.456 1.00 64.64  ? 114 ARG B O   1 
ATOM   2637 C CB  . ARG B 1 40  ? 134.909 96.210  101.746 1.00 67.74  ? 114 ARG B CB  1 
ATOM   2638 C CG  . ARG B 1 40  ? 135.521 94.845  102.018 1.00 69.74  ? 114 ARG B CG  1 
ATOM   2639 C CD  . ARG B 1 40  ? 134.504 93.760  102.334 1.00 68.81  ? 114 ARG B CD  1 
ATOM   2640 N NE  . ARG B 1 40  ? 135.143 92.487  102.655 1.00 69.23  ? 114 ARG B NE  1 
ATOM   2641 C CZ  . ARG B 1 40  ? 134.492 91.413  103.077 1.00 69.13  ? 114 ARG B CZ  1 
ATOM   2642 N NH1 . ARG B 1 40  ? 133.174 91.450  103.228 1.00 68.55  ? 114 ARG B NH1 1 
ATOM   2643 N NH2 . ARG B 1 40  ? 135.155 90.296  103.347 1.00 66.53  ? 114 ARG B NH2 1 
ATOM   2644 N N   . ASP B 1 41  ? 135.796 99.200  99.891  1.00 60.48  ? 115 ASP B N   1 
ATOM   2645 C CA  . ASP B 1 41  ? 135.204 100.388 99.282  1.00 61.12  ? 115 ASP B CA  1 
ATOM   2646 C C   . ASP B 1 41  ? 135.428 100.293 97.780  1.00 61.05  ? 115 ASP B C   1 
ATOM   2647 O O   . ASP B 1 41  ? 136.563 100.427 97.312  1.00 61.83  ? 115 ASP B O   1 
ATOM   2648 C CB  . ASP B 1 41  ? 135.813 101.669 99.852  1.00 63.85  ? 115 ASP B CB  1 
ATOM   2649 C CG  . ASP B 1 41  ? 134.939 102.887 99.617  1.00 65.37  ? 115 ASP B CG  1 
ATOM   2650 O OD1 . ASP B 1 41  ? 134.665 103.208 98.441  1.00 64.28  ? 115 ASP B OD1 1 
ATOM   2651 O OD2 . ASP B 1 41  ? 134.525 103.523 100.609 1.00 66.92  ? 115 ASP B OD2 1 
ATOM   2652 N N   . ALA B 1 42  ? 134.348 100.066 97.029  1.00 56.97  ? 116 ALA B N   1 
ATOM   2653 C CA  . ALA B 1 42  ? 134.476 99.814  95.597  1.00 59.03  ? 116 ALA B CA  1 
ATOM   2654 C C   . ALA B 1 42  ? 134.992 101.032 94.843  1.00 55.35  ? 116 ALA B C   1 
ATOM   2655 O O   . ALA B 1 42  ? 135.558 100.891 93.753  1.00 60.86  ? 116 ALA B O   1 
ATOM   2656 C CB  . ALA B 1 42  ? 133.131 99.367  95.022  1.00 59.99  ? 116 ALA B CB  1 
ATOM   2657 N N   . SER B 1 43  ? 134.812 102.229 95.398  1.00 46.15  ? 117 SER B N   1 
ATOM   2658 C CA  . SER B 1 43  ? 135.228 103.446 94.715  1.00 51.34  ? 117 SER B CA  1 
ATOM   2659 C C   . SER B 1 43  ? 136.732 103.679 94.765  1.00 53.00  ? 117 SER B C   1 
ATOM   2660 O O   . SER B 1 43  ? 137.235 104.512 94.004  1.00 54.04  ? 117 SER B O   1 
ATOM   2661 C CB  . SER B 1 43  ? 134.507 104.657 95.312  1.00 52.71  ? 117 SER B CB  1 
ATOM   2662 O OG  . SER B 1 43  ? 134.985 105.865 94.746  1.00 52.34  ? 117 SER B OG  1 
ATOM   2663 N N   . LEU B 1 44  ? 137.457 102.975 95.631  1.00 51.50  ? 118 LEU B N   1 
ATOM   2664 C CA  . LEU B 1 44  ? 138.883 103.202 95.810  1.00 46.49  ? 118 LEU B CA  1 
ATOM   2665 C C   . LEU B 1 44  ? 139.756 102.225 95.036  1.00 51.26  ? 118 LEU B C   1 
ATOM   2666 O O   . LEU B 1 44  ? 140.983 102.326 95.115  1.00 56.91  ? 118 LEU B O   1 
ATOM   2667 C CB  . LEU B 1 44  ? 139.248 103.136 97.297  1.00 48.18  ? 118 LEU B CB  1 
ATOM   2668 C CG  . LEU B 1 44  ? 138.332 103.846 98.293  1.00 49.70  ? 118 LEU B CG  1 
ATOM   2669 C CD1 . LEU B 1 44  ? 138.939 103.802 99.680  1.00 50.32  ? 118 LEU B CD1 1 
ATOM   2670 C CD2 . LEU B 1 44  ? 138.072 105.278 97.872  1.00 46.48  ? 118 LEU B CD2 1 
ATOM   2671 N N   . LEU B 1 45  ? 139.166 101.285 94.294  1.00 50.66  ? 119 LEU B N   1 
ATOM   2672 C CA  . LEU B 1 45  ? 139.975 100.298 93.583  1.00 44.00  ? 119 LEU B CA  1 
ATOM   2673 C C   . LEU B 1 45  ? 140.802 100.949 92.481  1.00 47.06  ? 119 LEU B C   1 
ATOM   2674 O O   . LEU B 1 45  ? 142.016 100.734 92.393  1.00 50.32  ? 119 LEU B O   1 
ATOM   2675 C CB  . LEU B 1 45  ? 139.090 99.190  93.010  1.00 44.33  ? 119 LEU B CB  1 
ATOM   2676 C CG  . LEU B 1 45  ? 138.673 98.032  93.925  1.00 51.68  ? 119 LEU B CG  1 
ATOM   2677 C CD1 . LEU B 1 45  ? 139.897 97.239  94.363  1.00 50.18  ? 119 LEU B CD1 1 
ATOM   2678 C CD2 . LEU B 1 45  ? 137.872 98.496  95.130  1.00 50.33  ? 119 LEU B CD2 1 
ATOM   2679 N N   . GLN B 1 46  ? 140.162 101.749 91.630  1.00 45.98  ? 120 GLN B N   1 
ATOM   2680 C CA  . GLN B 1 46  ? 140.896 102.418 90.558  1.00 43.38  ? 120 GLN B CA  1 
ATOM   2681 C C   . GLN B 1 46  ? 141.956 103.379 91.083  1.00 45.24  ? 120 GLN B C   1 
ATOM   2682 O O   . GLN B 1 46  ? 143.101 103.322 90.598  1.00 51.58  ? 120 GLN B O   1 
ATOM   2683 C CB  . GLN B 1 46  ? 139.911 103.121 89.617  1.00 43.65  ? 120 GLN B CB  1 
ATOM   2684 C CG  . GLN B 1 46  ? 140.563 103.780 88.414  1.00 48.64  ? 120 GLN B CG  1 
ATOM   2685 C CD  . GLN B 1 46  ? 141.265 102.785 87.513  1.00 52.05  ? 120 GLN B CD  1 
ATOM   2686 O OE1 . GLN B 1 46  ? 142.493 102.698 87.504  1.00 51.00  ? 120 GLN B OE1 1 
ATOM   2687 N NE2 . GLN B 1 46  ? 140.488 102.028 86.748  1.00 54.43  ? 120 GLN B NE2 1 
ATOM   2688 N N   . PRO B 1 47  ? 141.667 104.276 92.038  1.00 43.23  ? 121 PRO B N   1 
ATOM   2689 C CA  . PRO B 1 47  ? 142.752 105.106 92.586  1.00 43.23  ? 121 PRO B CA  1 
ATOM   2690 C C   . PRO B 1 47  ? 143.865 104.295 93.223  1.00 39.85  ? 121 PRO B C   1 
ATOM   2691 O O   . PRO B 1 47  ? 145.039 104.657 93.086  1.00 44.68  ? 121 PRO B O   1 
ATOM   2692 C CB  . PRO B 1 47  ? 142.027 105.987 93.611  1.00 41.49  ? 121 PRO B CB  1 
ATOM   2693 C CG  . PRO B 1 47  ? 140.631 106.044 93.123  1.00 43.72  ? 121 PRO B CG  1 
ATOM   2694 C CD  . PRO B 1 47  ? 140.366 104.665 92.611  1.00 45.73  ? 121 PRO B CD  1 
ATOM   2695 N N   . PHE B 1 48  ? 143.531 103.200 93.909  1.00 30.18  ? 122 PHE B N   1 
ATOM   2696 C CA  . PHE B 1 48  ? 144.559 102.373 94.534  1.00 28.42  ? 122 PHE B CA  1 
ATOM   2697 C C   . PHE B 1 48  ? 145.482 101.765 93.487  1.00 44.42  ? 122 PHE B C   1 
ATOM   2698 O O   . PHE B 1 48  ? 146.710 101.806 93.626  1.00 51.82  ? 122 PHE B O   1 
ATOM   2699 C CB  . PHE B 1 48  ? 143.909 101.276 95.376  1.00 36.00  ? 122 PHE B CB  1 
ATOM   2700 C CG  . PHE B 1 48  ? 144.892 100.368 96.056  1.00 31.64  ? 122 PHE B CG  1 
ATOM   2701 C CD1 . PHE B 1 48  ? 145.751 100.855 97.023  1.00 36.19  ? 122 PHE B CD1 1 
ATOM   2702 C CD2 . PHE B 1 48  ? 144.958 99.026  95.724  1.00 36.50  ? 122 PHE B CD2 1 
ATOM   2703 C CE1 . PHE B 1 48  ? 146.653 100.021 97.650  1.00 38.81  ? 122 PHE B CE1 1 
ATOM   2704 C CE2 . PHE B 1 48  ? 145.861 98.188  96.345  1.00 33.43  ? 122 PHE B CE2 1 
ATOM   2705 C CZ  . PHE B 1 48  ? 146.709 98.686  97.309  1.00 38.54  ? 122 PHE B CZ  1 
ATOM   2706 N N   . LYS B 1 49  ? 144.903 101.197 92.426  1.00 49.98  ? 123 LYS B N   1 
ATOM   2707 C CA  . LYS B 1 49  ? 145.717 100.609 91.368  1.00 47.47  ? 123 LYS B CA  1 
ATOM   2708 C C   . LYS B 1 49  ? 146.569 101.664 90.676  1.00 44.32  ? 123 LYS B C   1 
ATOM   2709 O O   . LYS B 1 49  ? 147.752 101.433 90.405  1.00 53.41  ? 123 LYS B O   1 
ATOM   2710 C CB  . LYS B 1 49  ? 144.831 99.889  90.352  1.00 51.93  ? 123 LYS B CB  1 
ATOM   2711 C CG  . LYS B 1 49  ? 144.003 98.757  90.931  1.00 51.50  ? 123 LYS B CG  1 
ATOM   2712 C CD  . LYS B 1 49  ? 142.973 98.267  89.928  1.00 53.78  ? 123 LYS B CD  1 
ATOM   2713 C CE  . LYS B 1 49  ? 142.076 97.201  90.533  1.00 53.82  ? 123 LYS B CE  1 
ATOM   2714 N NZ  . LYS B 1 49  ? 140.723 97.201  89.913  1.00 52.76  ? 123 LYS B NZ  1 
ATOM   2715 N N   . GLU B 1 50  ? 145.988 102.831 90.387  1.00 34.17  ? 124 GLU B N   1 
ATOM   2716 C CA  . GLU B 1 50  ? 146.747 103.886 89.723  1.00 33.05  ? 124 GLU B CA  1 
ATOM   2717 C C   . GLU B 1 50  ? 147.913 104.351 90.587  1.00 44.88  ? 124 GLU B C   1 
ATOM   2718 O O   . GLU B 1 50  ? 149.043 104.502 90.102  1.00 52.45  ? 124 GLU B O   1 
ATOM   2719 C CB  . GLU B 1 50  ? 145.826 105.057 89.384  1.00 39.28  ? 124 GLU B CB  1 
ATOM   2720 C CG  . GLU B 1 50  ? 146.367 105.985 88.312  1.00 46.52  ? 124 GLU B CG  1 
ATOM   2721 C CD  . GLU B 1 50  ? 145.325 106.965 87.811  1.00 51.15  ? 124 GLU B CD  1 
ATOM   2722 O OE1 . GLU B 1 50  ? 144.126 106.615 87.818  1.00 48.91  ? 124 GLU B OE1 1 
ATOM   2723 O OE2 . GLU B 1 50  ? 145.705 108.085 87.410  1.00 54.32  ? 124 GLU B OE2 1 
ATOM   2724 N N   . LEU B 1 51  ? 147.660 104.567 91.880  1.00 46.54  ? 125 LEU B N   1 
ATOM   2725 C CA  . LEU B 1 51  ? 148.710 105.035 92.775  1.00 40.41  ? 125 LEU B CA  1 
ATOM   2726 C C   . LEU B 1 51  ? 149.799 103.986 92.950  1.00 36.57  ? 125 LEU B C   1 
ATOM   2727 O O   . LEU B 1 51  ? 150.988 104.320 92.965  1.00 42.76  ? 125 LEU B O   1 
ATOM   2728 C CB  . LEU B 1 51  ? 148.110 105.423 94.126  1.00 41.27  ? 125 LEU B CB  1 
ATOM   2729 C CG  . LEU B 1 51  ? 149.090 105.864 95.213  1.00 39.23  ? 125 LEU B CG  1 
ATOM   2730 C CD1 . LEU B 1 51  ? 149.557 107.287 94.966  1.00 38.52  ? 125 LEU B CD1 1 
ATOM   2731 C CD2 . LEU B 1 51  ? 148.449 105.740 96.584  1.00 42.62  ? 125 LEU B CD2 1 
ATOM   2732 N N   . CYS B 1 52  ? 149.420 102.712 93.079  1.00 39.04  ? 126 CYS B N   1 
ATOM   2733 C CA  . CYS B 1 52  ? 150.424 101.665 93.236  1.00 42.67  ? 126 CYS B CA  1 
ATOM   2734 C C   . CYS B 1 52  ? 151.243 101.489 91.965  1.00 50.68  ? 126 CYS B C   1 
ATOM   2735 O O   . CYS B 1 52  ? 152.449 101.222 92.030  1.00 56.36  ? 126 CYS B O   1 
ATOM   2736 C CB  . CYS B 1 52  ? 149.755 100.351 93.634  1.00 46.40  ? 126 CYS B CB  1 
ATOM   2737 S SG  . CYS B 1 52  ? 149.234 100.284 95.360  1.00 60.42  ? 126 CYS B SG  1 
ATOM   2738 N N   . THR B 1 53  ? 150.608 101.629 90.798  1.00 44.50  ? 127 THR B N   1 
ATOM   2739 C CA  . THR B 1 53  ? 151.348 101.560 89.544  1.00 36.01  ? 127 THR B CA  1 
ATOM   2740 C C   . THR B 1 53  ? 152.333 102.715 89.425  1.00 37.31  ? 127 THR B C   1 
ATOM   2741 O O   . THR B 1 53  ? 153.477 102.523 88.997  1.00 46.37  ? 127 THR B O   1 
ATOM   2742 C CB  . THR B 1 53  ? 150.378 101.557 88.363  1.00 43.43  ? 127 THR B CB  1 
ATOM   2743 O OG1 . THR B 1 53  ? 149.502 100.428 88.466  1.00 48.61  ? 127 THR B OG1 1 
ATOM   2744 C CG2 . THR B 1 53  ? 151.137 101.480 87.048  1.00 47.55  ? 127 THR B CG2 1 
ATOM   2745 N N   . HIS B 1 54  ? 151.909 103.924 89.801  1.00 39.69  ? 128 HIS B N   1 
ATOM   2746 C CA  . HIS B 1 54  ? 152.812 105.069 89.719  1.00 39.62  ? 128 HIS B CA  1 
ATOM   2747 C C   . HIS B 1 54  ? 153.963 104.952 90.711  1.00 42.82  ? 128 HIS B C   1 
ATOM   2748 O O   . HIS B 1 54  ? 155.112 105.248 90.368  1.00 46.78  ? 128 HIS B O   1 
ATOM   2749 C CB  . HIS B 1 54  ? 152.049 106.371 89.946  1.00 34.87  ? 128 HIS B CB  1 
ATOM   2750 C CG  . HIS B 1 54  ? 152.921 107.587 89.913  1.00 38.29  ? 128 HIS B CG  1 
ATOM   2751 N ND1 . HIS B 1 54  ? 153.444 108.096 88.744  1.00 45.00  ? 128 HIS B ND1 1 
ATOM   2752 C CD2 . HIS B 1 54  ? 153.374 108.387 90.907  1.00 43.45  ? 128 HIS B CD2 1 
ATOM   2753 C CE1 . HIS B 1 54  ? 154.178 109.160 89.020  1.00 43.43  ? 128 HIS B CE1 1 
ATOM   2754 N NE2 . HIS B 1 54  ? 154.150 109.359 90.325  1.00 40.44  ? 128 HIS B NE2 1 
ATOM   2755 N N   . LEU B 1 55  ? 153.678 104.526 91.944  1.00 46.65  ? 129 LEU B N   1 
ATOM   2756 C CA  . LEU B 1 55  ? 154.713 104.501 92.974  1.00 41.24  ? 129 LEU B CA  1 
ATOM   2757 C C   . LEU B 1 55  ? 155.831 103.523 92.635  1.00 44.86  ? 129 LEU B C   1 
ATOM   2758 O O   . LEU B 1 55  ? 156.970 103.712 93.077  1.00 53.23  ? 129 LEU B O   1 
ATOM   2759 C CB  . LEU B 1 55  ? 154.102 104.160 94.333  1.00 40.95  ? 129 LEU B CB  1 
ATOM   2760 C CG  . LEU B 1 55  ? 153.203 105.222 94.971  1.00 42.51  ? 129 LEU B CG  1 
ATOM   2761 C CD1 . LEU B 1 55  ? 152.851 104.845 96.401  1.00 46.49  ? 129 LEU B CD1 1 
ATOM   2762 C CD2 . LEU B 1 55  ? 153.845 106.598 94.914  1.00 44.81  ? 129 LEU B CD2 1 
ATOM   2763 N N   . MET B 1 56  ? 155.535 102.478 91.862  1.00 48.44  ? 130 MET B N   1 
ATOM   2764 C CA  . MET B 1 56  ? 156.546 101.526 91.420  1.00 47.22  ? 130 MET B CA  1 
ATOM   2765 C C   . MET B 1 56  ? 157.017 101.794 89.995  1.00 46.52  ? 130 MET B C   1 
ATOM   2766 O O   . MET B 1 56  ? 157.428 100.866 89.291  1.00 53.33  ? 130 MET B O   1 
ATOM   2767 C CB  . MET B 1 56  ? 156.036 100.093 91.560  1.00 42.83  ? 130 MET B CB  1 
ATOM   2768 C CG  . MET B 1 56  ? 155.829 99.667  93.002  1.00 47.40  ? 130 MET B CG  1 
ATOM   2769 S SD  . MET B 1 56  ? 155.290 97.958  93.171  1.00 55.04  ? 130 MET B SD  1 
ATOM   2770 C CE  . MET B 1 56  ? 153.590 98.099  92.643  1.00 50.53  ? 130 MET B CE  1 
ATOM   2771 N N   . GLU B 1 57  ? 156.963 103.051 89.554  1.00 46.72  ? 131 GLU B N   1 
ATOM   2772 C CA  . GLU B 1 57  ? 157.646 103.469 88.341  1.00 45.46  ? 131 GLU B CA  1 
ATOM   2773 C C   . GLU B 1 57  ? 158.885 104.304 88.629  1.00 50.58  ? 131 GLU B C   1 
ATOM   2774 O O   . GLU B 1 57  ? 159.681 104.538 87.713  1.00 58.76  ? 131 GLU B O   1 
ATOM   2775 C CB  . GLU B 1 57  ? 156.696 104.254 87.422  1.00 47.20  ? 131 GLU B CB  1 
ATOM   2776 C CG  . GLU B 1 57  ? 156.653 105.749 87.677  1.00 52.26  ? 131 GLU B CG  1 
ATOM   2777 C CD  . GLU B 1 57  ? 155.761 106.481 86.694  1.00 57.88  ? 131 GLU B CD  1 
ATOM   2778 O OE1 . GLU B 1 57  ? 154.868 105.836 86.105  1.00 59.52  ? 131 GLU B OE1 1 
ATOM   2779 O OE2 . GLU B 1 57  ? 155.951 107.702 86.511  1.00 57.29  ? 131 GLU B OE2 1 
ATOM   2780 N N   . GLU B 1 58  ? 159.069 104.754 89.871  1.00 44.56  ? 132 GLU B N   1 
ATOM   2781 C CA  . GLU B 1 58  ? 160.317 105.356 90.319  1.00 48.77  ? 132 GLU B CA  1 
ATOM   2782 C C   . GLU B 1 58  ? 161.162 104.382 91.132  1.00 49.48  ? 132 GLU B C   1 
ATOM   2783 O O   . GLU B 1 58  ? 162.035 104.816 91.892  1.00 52.05  ? 132 GLU B O   1 
ATOM   2784 C CB  . GLU B 1 58  ? 160.049 106.621 91.137  1.00 46.42  ? 132 GLU B CB  1 
ATOM   2785 C CG  . GLU B 1 58  ? 159.451 107.778 90.353  1.00 49.21  ? 132 GLU B CG  1 
ATOM   2786 C CD  . GLU B 1 58  ? 157.952 107.664 90.199  1.00 51.45  ? 132 GLU B CD  1 
ATOM   2787 O OE1 . GLU B 1 58  ? 157.372 106.713 90.760  1.00 52.21  ? 132 GLU B OE1 1 
ATOM   2788 O OE2 . GLU B 1 58  ? 157.353 108.522 89.518  1.00 51.88  ? 132 GLU B OE2 1 
ATOM   2789 N N   . ASN B 1 59  ? 160.913 103.078 90.987  1.00 54.41  ? 133 ASN B N   1 
ATOM   2790 C CA  . ASN B 1 59  ? 161.667 102.036 91.685  1.00 56.73  ? 133 ASN B CA  1 
ATOM   2791 C C   . ASN B 1 59  ? 161.645 102.256 93.197  1.00 56.50  ? 133 ASN B C   1 
ATOM   2792 O O   . ASN B 1 59  ? 162.671 102.181 93.877  1.00 61.24  ? 133 ASN B O   1 
ATOM   2793 C CB  . ASN B 1 59  ? 163.103 101.954 91.160  1.00 57.66  ? 133 ASN B CB  1 
ATOM   2794 C CG  . ASN B 1 59  ? 163.700 100.568 91.308  1.00 60.55  ? 133 ASN B CG  1 
ATOM   2795 O OD1 . ASN B 1 59  ? 163.485 99.890  92.313  1.00 59.21  ? 133 ASN B OD1 1 
ATOM   2796 N ND2 . ASN B 1 59  ? 164.455 100.140 90.303  1.00 60.59  ? 133 ASN B ND2 1 
ATOM   2797 N N   . MET B 1 60  ? 160.456 102.535 93.724  1.00 51.71  ? 134 MET B N   1 
ATOM   2798 C CA  . MET B 1 60  ? 160.269 102.824 95.138  1.00 49.56  ? 134 MET B CA  1 
ATOM   2799 C C   . MET B 1 60  ? 159.406 101.737 95.763  1.00 44.41  ? 134 MET B C   1 
ATOM   2800 O O   . MET B 1 60  ? 158.315 101.441 95.266  1.00 50.78  ? 134 MET B O   1 
ATOM   2801 C CB  . MET B 1 60  ? 159.640 104.208 95.329  1.00 50.13  ? 134 MET B CB  1 
ATOM   2802 C CG  . MET B 1 60  ? 159.455 104.623 96.775  1.00 49.50  ? 134 MET B CG  1 
ATOM   2803 S SD  . MET B 1 60  ? 158.741 106.270 96.922  1.00 61.32  ? 134 MET B SD  1 
ATOM   2804 C CE  . MET B 1 60  ? 157.063 105.957 96.395  1.00 54.77  ? 134 MET B CE  1 
ATOM   2805 N N   . ILE B 1 61  ? 159.904 101.143 96.849  1.00 40.97  ? 135 ILE B N   1 
ATOM   2806 C CA  . ILE B 1 61  ? 159.245 99.999  97.466  1.00 38.18  ? 135 ILE B CA  1 
ATOM   2807 C C   . ILE B 1 61  ? 157.931 100.435 98.101  1.00 45.33  ? 135 ILE B C   1 
ATOM   2808 O O   . ILE B 1 61  ? 157.845 101.496 98.734  1.00 52.65  ? 135 ILE B O   1 
ATOM   2809 C CB  . ILE B 1 61  ? 160.177 99.346  98.501  1.00 39.03  ? 135 ILE B CB  1 
ATOM   2810 C CG1 . ILE B 1 61  ? 161.455 98.848  97.825  1.00 45.17  ? 135 ILE B CG1 1 
ATOM   2811 C CG2 . ILE B 1 61  ? 159.484 98.192  99.202  1.00 41.00  ? 135 ILE B CG2 1 
ATOM   2812 C CD1 . ILE B 1 61  ? 162.534 98.426  98.797  1.00 47.73  ? 135 ILE B CD1 1 
ATOM   2813 N N   . VAL B 1 62  ? 156.895 99.616  97.930  1.00 30.48  ? 136 VAL B N   1 
ATOM   2814 C CA  . VAL B 1 62  ? 155.567 99.904  98.454  1.00 26.90  ? 136 VAL B CA  1 
ATOM   2815 C C   . VAL B 1 62  ? 155.142 98.777  99.386  1.00 34.00  ? 136 VAL B C   1 
ATOM   2816 O O   . VAL B 1 62  ? 155.510 97.613  99.197  1.00 41.93  ? 136 VAL B O   1 
ATOM   2817 C CB  . VAL B 1 62  ? 154.537 100.098 97.322  1.00 24.76  ? 136 VAL B CB  1 
ATOM   2818 C CG1 . VAL B 1 62  ? 154.923 101.277 96.452  1.00 38.25  ? 136 VAL B CG1 1 
ATOM   2819 C CG2 . VAL B 1 62  ? 154.443 98.849  96.484  1.00 37.70  ? 136 VAL B CG2 1 
ATOM   2820 N N   . TYR B 1 63  ? 154.367 99.135  100.408 1.00 39.51  ? 137 TYR B N   1 
ATOM   2821 C CA  . TYR B 1 63  ? 153.855 98.189  101.389 1.00 33.64  ? 137 TYR B CA  1 
ATOM   2822 C C   . TYR B 1 63  ? 152.333 98.229  101.395 1.00 39.44  ? 137 TYR B C   1 
ATOM   2823 O O   . TYR B 1 63  ? 151.731 99.304  101.308 1.00 49.68  ? 137 TYR B O   1 
ATOM   2824 C CB  . TYR B 1 63  ? 154.385 98.492  102.795 1.00 40.02  ? 137 TYR B CB  1 
ATOM   2825 C CG  . TYR B 1 63  ? 155.817 98.066  103.031 1.00 40.90  ? 137 TYR B CG  1 
ATOM   2826 C CD1 . TYR B 1 63  ? 156.854 98.582  102.267 1.00 41.18  ? 137 TYR B CD1 1 
ATOM   2827 C CD2 . TYR B 1 63  ? 156.130 97.145  104.021 1.00 42.18  ? 137 TYR B CD2 1 
ATOM   2828 C CE1 . TYR B 1 63  ? 158.161 98.194  102.483 1.00 42.76  ? 137 TYR B CE1 1 
ATOM   2829 C CE2 . TYR B 1 63  ? 157.434 96.750  104.244 1.00 41.89  ? 137 TYR B CE2 1 
ATOM   2830 C CZ  . TYR B 1 63  ? 158.445 97.278  103.472 1.00 42.27  ? 137 TYR B CZ  1 
ATOM   2831 O OH  . TYR B 1 63  ? 159.746 96.889  103.689 1.00 44.27  ? 137 TYR B OH  1 
ATOM   2832 N N   . VAL B 1 64  ? 151.716 97.053  101.492 1.00 41.43  ? 138 VAL B N   1 
ATOM   2833 C CA  . VAL B 1 64  ? 150.264 96.914  101.457 1.00 40.02  ? 138 VAL B CA  1 
ATOM   2834 C C   . VAL B 1 64  ? 149.846 95.903  102.518 1.00 45.99  ? 138 VAL B C   1 
ATOM   2835 O O   . VAL B 1 64  ? 150.550 94.918  102.763 1.00 51.89  ? 138 VAL B O   1 
ATOM   2836 C CB  . VAL B 1 64  ? 149.769 96.477  100.059 1.00 47.32  ? 138 VAL B CB  1 
ATOM   2837 C CG1 . VAL B 1 64  ? 148.264 96.260  100.054 1.00 49.74  ? 138 VAL B CG1 1 
ATOM   2838 C CG2 . VAL B 1 64  ? 150.152 97.500  99.003  1.00 47.55  ? 138 VAL B CG2 1 
ATOM   2839 N N   . GLU B 1 65  ? 148.704 96.157  103.157 1.00 54.79  ? 139 GLU B N   1 
ATOM   2840 C CA  . GLU B 1 65  ? 148.107 95.179  104.057 1.00 56.24  ? 139 GLU B CA  1 
ATOM   2841 C C   . GLU B 1 65  ? 147.822 93.878  103.315 1.00 64.35  ? 139 GLU B C   1 
ATOM   2842 O O   . GLU B 1 65  ? 147.435 93.884  102.143 1.00 67.42  ? 139 GLU B O   1 
ATOM   2843 C CB  . GLU B 1 65  ? 146.812 95.738  104.653 1.00 60.83  ? 139 GLU B CB  1 
ATOM   2844 C CG  . GLU B 1 65  ? 146.094 94.810  105.628 1.00 64.39  ? 139 GLU B CG  1 
ATOM   2845 C CD  . GLU B 1 65  ? 146.879 94.552  106.896 1.00 67.32  ? 139 GLU B CD  1 
ATOM   2846 O OE1 . GLU B 1 65  ? 147.699 95.413  107.274 1.00 67.02  ? 139 GLU B OE1 1 
ATOM   2847 O OE2 . GLU B 1 65  ? 146.676 93.487  107.517 1.00 66.31  ? 139 GLU B OE2 1 
ATOM   2848 N N   . LYS B 1 66  ? 148.025 92.753  104.007 1.00 66.58  ? 140 LYS B N   1 
ATOM   2849 C CA  . LYS B 1 66  ? 147.808 91.450  103.384 1.00 61.14  ? 140 LYS B CA  1 
ATOM   2850 C C   . LYS B 1 66  ? 146.351 91.263  102.979 1.00 61.44  ? 140 LYS B C   1 
ATOM   2851 O O   . LYS B 1 66  ? 146.063 90.688  101.923 1.00 67.65  ? 140 LYS B O   1 
ATOM   2852 C CB  . LYS B 1 66  ? 148.246 90.333  104.331 1.00 62.18  ? 140 LYS B CB  1 
ATOM   2853 C CG  . LYS B 1 66  ? 148.138 88.939  103.735 1.00 67.27  ? 140 LYS B CG  1 
ATOM   2854 C CD  . LYS B 1 66  ? 148.638 87.881  104.704 1.00 67.86  ? 140 LYS B CD  1 
ATOM   2855 C CE  . LYS B 1 66  ? 148.616 86.498  104.073 1.00 64.98  ? 140 LYS B CE  1 
ATOM   2856 N NZ  . LYS B 1 66  ? 147.228 86.027  103.815 1.00 63.81  ? 140 LYS B NZ  1 
ATOM   2857 N N   . LYS B 1 67  ? 145.419 91.740  103.806 1.00 60.06  ? 141 LYS B N   1 
ATOM   2858 C CA  . LYS B 1 67  ? 144.002 91.558  103.513 1.00 62.69  ? 141 LYS B CA  1 
ATOM   2859 C C   . LYS B 1 67  ? 143.560 92.321  102.272 1.00 63.83  ? 141 LYS B C   1 
ATOM   2860 O O   . LYS B 1 67  ? 142.545 91.960  101.667 1.00 67.29  ? 141 LYS B O   1 
ATOM   2861 C CB  . LYS B 1 67  ? 143.159 91.984  104.716 1.00 65.32  ? 141 LYS B CB  1 
ATOM   2862 C CG  . LYS B 1 67  ? 143.284 91.061  105.917 1.00 67.10  ? 141 LYS B CG  1 
ATOM   2863 C CD  . LYS B 1 67  ? 142.485 91.581  107.101 1.00 67.58  ? 141 LYS B CD  1 
ATOM   2864 C CE  . LYS B 1 67  ? 140.990 91.448  106.859 1.00 67.42  ? 141 LYS B CE  1 
ATOM   2865 N NZ  . LYS B 1 67  ? 140.559 90.023  106.827 1.00 65.13  ? 141 LYS B NZ  1 
ATOM   2866 N N   . VAL B 1 68  ? 144.290 93.368  101.879 1.00 59.96  ? 142 VAL B N   1 
ATOM   2867 C CA  . VAL B 1 68  ? 143.939 94.096  100.664 1.00 61.11  ? 142 VAL B CA  1 
ATOM   2868 C C   . VAL B 1 68  ? 144.170 93.227  99.434  1.00 64.24  ? 142 VAL B C   1 
ATOM   2869 O O   . VAL B 1 68  ? 143.350 93.207  98.509  1.00 66.90  ? 142 VAL B O   1 
ATOM   2870 C CB  . VAL B 1 68  ? 144.727 95.416  100.583 1.00 64.48  ? 142 VAL B CB  1 
ATOM   2871 C CG1 . VAL B 1 68  ? 144.261 96.237  99.393  1.00 63.15  ? 142 VAL B CG1 1 
ATOM   2872 C CG2 . VAL B 1 68  ? 144.563 96.206  101.869 1.00 64.41  ? 142 VAL B CG2 1 
ATOM   2873 N N   . LEU B 1 69  ? 145.288 92.501  99.399  1.00 60.04  ? 143 LEU B N   1 
ATOM   2874 C CA  . LEU B 1 69  ? 145.537 91.574  98.302  1.00 63.36  ? 143 LEU B CA  1 
ATOM   2875 C C   . LEU B 1 69  ? 144.611 90.366  98.348  1.00 64.54  ? 143 LEU B C   1 
ATOM   2876 O O   . LEU B 1 69  ? 144.388 89.729  97.313  1.00 63.22  ? 143 LEU B O   1 
ATOM   2877 C CB  . LEU B 1 69  ? 146.996 91.120  98.320  1.00 62.43  ? 143 LEU B CB  1 
ATOM   2878 C CG  . LEU B 1 69  ? 148.025 92.248  98.399  1.00 62.16  ? 143 LEU B CG  1 
ATOM   2879 C CD1 . LEU B 1 69  ? 149.439 91.702  98.286  1.00 61.71  ? 143 LEU B CD1 1 
ATOM   2880 C CD2 . LEU B 1 69  ? 147.756 93.287  97.322  1.00 62.25  ? 143 LEU B CD2 1 
ATOM   2881 N N   . GLU B 1 70  ? 144.072 90.036  99.524  1.00 67.42  ? 144 GLU B N   1 
ATOM   2882 C CA  . GLU B 1 70  ? 143.115 88.945  99.656  1.00 64.03  ? 144 GLU B CA  1 
ATOM   2883 C C   . GLU B 1 70  ? 141.741 89.310  99.100  1.00 65.12  ? 144 GLU B C   1 
ATOM   2884 O O   . GLU B 1 70  ? 140.887 88.426  98.968  1.00 67.91  ? 144 GLU B O   1 
ATOM   2885 C CB  . GLU B 1 70  ? 143.021 88.538  101.133 1.00 67.19  ? 144 GLU B CB  1 
ATOM   2886 C CG  . GLU B 1 70  ? 142.134 87.338  101.438 1.00 68.60  ? 144 GLU B CG  1 
ATOM   2887 C CD  . GLU B 1 70  ? 142.134 86.974  102.910 1.00 72.63  ? 144 GLU B CD  1 
ATOM   2888 O OE1 . GLU B 1 70  ? 142.811 87.670  103.695 1.00 72.57  ? 144 GLU B OE1 1 
ATOM   2889 O OE2 . GLU B 1 70  ? 141.459 85.991  103.280 1.00 72.02  ? 144 GLU B OE2 1 
ATOM   2890 N N   . ASP B 1 71  ? 141.524 90.575  98.753  1.00 64.34  ? 145 ASP B N   1 
ATOM   2891 C CA  . ASP B 1 71  ? 140.239 91.013  98.225  1.00 65.33  ? 145 ASP B CA  1 
ATOM   2892 C C   . ASP B 1 71  ? 139.896 90.213  96.971  1.00 66.15  ? 145 ASP B C   1 
ATOM   2893 O O   . ASP B 1 71  ? 140.735 90.096  96.069  1.00 66.85  ? 145 ASP B O   1 
ATOM   2894 C CB  . ASP B 1 71  ? 140.298 92.510  97.905  1.00 67.07  ? 145 ASP B CB  1 
ATOM   2895 C CG  . ASP B 1 71  ? 138.944 93.103  97.545  1.00 69.64  ? 145 ASP B CG  1 
ATOM   2896 O OD1 . ASP B 1 71  ? 137.939 92.367  97.504  1.00 69.55  ? 145 ASP B OD1 1 
ATOM   2897 O OD2 . ASP B 1 71  ? 138.887 94.326  97.298  1.00 70.69  ? 145 ASP B OD2 1 
ATOM   2898 N N   . PRO B 1 72  ? 138.701 89.621  96.888  1.00 70.18  ? 146 PRO B N   1 
ATOM   2899 C CA  . PRO B 1 72  ? 138.334 88.909  95.653  1.00 68.25  ? 146 PRO B CA  1 
ATOM   2900 C C   . PRO B 1 72  ? 138.401 89.777  94.408  1.00 67.37  ? 146 PRO B C   1 
ATOM   2901 O O   . PRO B 1 72  ? 138.816 89.292  93.348  1.00 69.86  ? 146 PRO B O   1 
ATOM   2902 C CB  . PRO B 1 72  ? 136.905 88.434  95.945  1.00 69.03  ? 146 PRO B CB  1 
ATOM   2903 C CG  . PRO B 1 72  ? 136.883 88.256  97.424  1.00 69.88  ? 146 PRO B CG  1 
ATOM   2904 C CD  . PRO B 1 72  ? 137.739 89.366  97.976  1.00 71.17  ? 146 PRO B CD  1 
ATOM   2905 N N   . ALA B 1 73  ? 138.008 91.045  94.498  1.00 60.07  ? 147 ALA B N   1 
ATOM   2906 C CA  . ALA B 1 73  ? 138.057 91.932  93.336  1.00 62.12  ? 147 ALA B CA  1 
ATOM   2907 C C   . ALA B 1 73  ? 139.360 92.725  93.277  1.00 60.04  ? 147 ALA B C   1 
ATOM   2908 O O   . ALA B 1 73  ? 139.364 93.937  93.072  1.00 58.08  ? 147 ALA B O   1 
ATOM   2909 C CB  . ALA B 1 73  ? 136.851 92.863  93.346  1.00 61.79  ? 147 ALA B CB  1 
ATOM   2910 N N   . ILE B 1 74  ? 140.485 92.034  93.453  1.00 60.55  ? 148 ILE B N   1 
ATOM   2911 C CA  . ILE B 1 74  ? 141.792 92.613  93.156  1.00 59.75  ? 148 ILE B CA  1 
ATOM   2912 C C   . ILE B 1 74  ? 142.674 91.690  92.332  1.00 62.03  ? 148 ILE B C   1 
ATOM   2913 O O   . ILE B 1 74  ? 143.640 92.161  91.704  1.00 62.46  ? 148 ILE B O   1 
ATOM   2914 C CB  . ILE B 1 74  ? 142.517 93.032  94.458  1.00 61.96  ? 148 ILE B CB  1 
ATOM   2915 C CG1 . ILE B 1 74  ? 143.612 94.059  94.163  1.00 58.04  ? 148 ILE B CG1 1 
ATOM   2916 C CG2 . ILE B 1 74  ? 143.118 91.830  95.156  1.00 62.12  ? 148 ILE B CG2 1 
ATOM   2917 C CD1 . ILE B 1 74  ? 143.087 95.391  93.682  1.00 58.49  ? 148 ILE B CD1 1 
ATOM   2918 N N   . ALA B 1 75  ? 142.388 90.386  92.279  1.00 65.86  ? 149 ALA B N   1 
ATOM   2919 C CA  . ALA B 1 75  ? 143.141 89.454  91.444  1.00 65.83  ? 149 ALA B CA  1 
ATOM   2920 C C   . ALA B 1 75  ? 142.385 89.085  90.174  1.00 64.82  ? 149 ALA B C   1 
ATOM   2921 O O   . ALA B 1 75  ? 142.983 88.495  89.259  1.00 65.88  ? 149 ALA B O   1 
ATOM   2922 C CB  . ALA B 1 75  ? 143.484 88.201  92.235  1.00 63.46  ? 149 ALA B CB  1 
ATOM   2923 N N   . SER B 1 76  ? 141.098 89.427  90.080  1.00 67.57  ? 150 SER B N   1 
ATOM   2924 C CA  . SER B 1 76  ? 140.342 89.149  88.864  1.00 69.81  ? 150 SER B CA  1 
ATOM   2925 C C   . SER B 1 76  ? 140.923 89.899  87.673  1.00 71.80  ? 150 SER B C   1 
ATOM   2926 O O   . SER B 1 76  ? 141.007 89.355  86.566  1.00 73.30  ? 150 SER B O   1 
ATOM   2927 C CB  . SER B 1 76  ? 138.872 89.514  89.065  1.00 70.97  ? 150 SER B CB  1 
ATOM   2928 O OG  . SER B 1 76  ? 138.308 88.784  90.140  1.00 72.14  ? 150 SER B OG  1 
ATOM   2929 N N   . ASP B 1 77  ? 141.329 91.150  87.880  1.00 70.49  ? 151 ASP B N   1 
ATOM   2930 C CA  . ASP B 1 77  ? 141.956 91.941  86.827  1.00 71.48  ? 151 ASP B CA  1 
ATOM   2931 C C   . ASP B 1 77  ? 143.411 91.509  86.697  1.00 68.70  ? 151 ASP B C   1 
ATOM   2932 O O   . ASP B 1 77  ? 144.233 91.795  87.573  1.00 68.53  ? 151 ASP B O   1 
ATOM   2933 C CB  . ASP B 1 77  ? 141.848 93.430  87.142  1.00 72.02  ? 151 ASP B CB  1 
ATOM   2934 C CG  . ASP B 1 77  ? 142.620 94.292  86.162  1.00 74.27  ? 151 ASP B CG  1 
ATOM   2935 O OD1 . ASP B 1 77  ? 142.715 93.910  84.977  1.00 73.39  ? 151 ASP B OD1 1 
ATOM   2936 O OD2 . ASP B 1 77  ? 143.134 95.351  86.578  1.00 72.85  ? 151 ASP B OD2 1 
ATOM   2937 N N   . GLU B 1 78  ? 143.731 90.816  85.603  1.00 72.35  ? 152 GLU B N   1 
ATOM   2938 C CA  . GLU B 1 78  ? 145.090 90.339  85.383  1.00 72.91  ? 152 GLU B CA  1 
ATOM   2939 C C   . GLU B 1 78  ? 146.043 91.449  84.964  1.00 72.63  ? 152 GLU B C   1 
ATOM   2940 O O   . GLU B 1 78  ? 147.261 91.247  85.007  1.00 75.87  ? 152 GLU B O   1 
ATOM   2941 C CB  . GLU B 1 78  ? 145.095 89.229  84.329  1.00 73.97  ? 152 GLU B CB  1 
ATOM   2942 C CG  . GLU B 1 78  ? 144.772 89.701  82.919  1.00 76.82  ? 152 GLU B CG  1 
ATOM   2943 C CD  . GLU B 1 78  ? 143.281 89.739  82.639  1.00 78.71  ? 152 GLU B CD  1 
ATOM   2944 O OE1 . GLU B 1 78  ? 142.487 89.687  83.602  1.00 77.64  ? 152 GLU B OE1 1 
ATOM   2945 O OE2 . GLU B 1 78  ? 142.902 89.820  81.451  1.00 76.82  ? 152 GLU B OE2 1 
ATOM   2946 N N   . SER B 1 79  ? 145.520 92.607  84.555  1.00 61.36  ? 153 SER B N   1 
ATOM   2947 C CA  . SER B 1 79  ? 146.389 93.727  84.210  1.00 65.07  ? 153 SER B CA  1 
ATOM   2948 C C   . SER B 1 79  ? 147.167 94.211  85.427  1.00 66.06  ? 153 SER B C   1 
ATOM   2949 O O   . SER B 1 79  ? 148.356 94.537  85.326  1.00 65.46  ? 153 SER B O   1 
ATOM   2950 C CB  . SER B 1 79  ? 145.565 94.866  83.610  1.00 65.93  ? 153 SER B CB  1 
ATOM   2951 O OG  . SER B 1 79  ? 146.383 95.980  83.301  1.00 68.18  ? 153 SER B OG  1 
ATOM   2952 N N   . PHE B 1 80  ? 146.512 94.265  86.586  1.00 61.47  ? 154 PHE B N   1 
ATOM   2953 C CA  . PHE B 1 80  ? 147.162 94.675  87.823  1.00 59.64  ? 154 PHE B CA  1 
ATOM   2954 C C   . PHE B 1 80  ? 147.965 93.554  88.469  1.00 60.87  ? 154 PHE B C   1 
ATOM   2955 O O   . PHE B 1 80  ? 148.708 93.818  89.421  1.00 68.13  ? 154 PHE B O   1 
ATOM   2956 C CB  . PHE B 1 80  ? 146.111 95.196  88.809  1.00 61.29  ? 154 PHE B CB  1 
ATOM   2957 C CG  . PHE B 1 80  ? 146.690 95.925  89.988  1.00 57.78  ? 154 PHE B CG  1 
ATOM   2958 C CD1 . PHE B 1 80  ? 147.505 97.029  89.805  1.00 58.64  ? 154 PHE B CD1 1 
ATOM   2959 C CD2 . PHE B 1 80  ? 146.418 95.507  91.279  1.00 59.06  ? 154 PHE B CD2 1 
ATOM   2960 C CE1 . PHE B 1 80  ? 148.037 97.701  90.888  1.00 60.78  ? 154 PHE B CE1 1 
ATOM   2961 C CE2 . PHE B 1 80  ? 146.948 96.174  92.366  1.00 61.91  ? 154 PHE B CE2 1 
ATOM   2962 C CZ  . PHE B 1 80  ? 147.758 97.273  92.170  1.00 61.82  ? 154 PHE B CZ  1 
ATOM   2963 N N   . GLY B 1 81  ? 147.837 92.319  87.979  1.00 54.36  ? 155 GLY B N   1 
ATOM   2964 C CA  . GLY B 1 81  ? 148.545 91.210  88.598  1.00 53.82  ? 155 GLY B CA  1 
ATOM   2965 C C   . GLY B 1 81  ? 150.053 91.334  88.489  1.00 53.53  ? 155 GLY B C   1 
ATOM   2966 O O   . GLY B 1 81  ? 150.780 91.026  89.436  1.00 56.17  ? 155 GLY B O   1 
ATOM   2967 N N   . ALA B 1 82  ? 150.544 91.777  87.329  1.00 50.81  ? 156 ALA B N   1 
ATOM   2968 C CA  . ALA B 1 82  ? 151.981 91.977  87.167  1.00 52.11  ? 156 ALA B CA  1 
ATOM   2969 C C   . ALA B 1 82  ? 152.486 93.075  88.091  1.00 49.12  ? 156 ALA B C   1 
ATOM   2970 O O   . ALA B 1 82  ? 153.566 92.955  88.681  1.00 50.37  ? 156 ALA B O   1 
ATOM   2971 C CB  . ALA B 1 82  ? 152.306 92.306  85.710  1.00 53.41  ? 156 ALA B CB  1 
ATOM   2972 N N   . VAL B 1 83  ? 151.717 94.157  88.225  1.00 54.46  ? 157 VAL B N   1 
ATOM   2973 C CA  . VAL B 1 83  ? 152.069 95.220  89.159  1.00 54.50  ? 157 VAL B CA  1 
ATOM   2974 C C   . VAL B 1 83  ? 151.950 94.729  90.597  1.00 52.31  ? 157 VAL B C   1 
ATOM   2975 O O   . VAL B 1 83  ? 152.710 95.159  91.474  1.00 54.11  ? 157 VAL B O   1 
ATOM   2976 C CB  . VAL B 1 83  ? 151.182 96.452  88.893  1.00 52.97  ? 157 VAL B CB  1 
ATOM   2977 C CG1 . VAL B 1 83  ? 151.478 97.560  89.882  1.00 51.07  ? 157 VAL B CG1 1 
ATOM   2978 C CG2 . VAL B 1 83  ? 151.374 96.943  87.465  1.00 55.04  ? 157 VAL B CG2 1 
ATOM   2979 N N   . LYS B 1 84  ? 151.014 93.814  90.859  1.00 53.48  ? 158 LYS B N   1 
ATOM   2980 C CA  . LYS B 1 84  ? 150.788 93.325  92.216  1.00 51.06  ? 158 LYS B CA  1 
ATOM   2981 C C   . LYS B 1 84  ? 151.994 92.578  92.772  1.00 50.79  ? 158 LYS B C   1 
ATOM   2982 O O   . LYS B 1 84  ? 152.295 92.691  93.965  1.00 54.31  ? 158 LYS B O   1 
ATOM   2983 C CB  . LYS B 1 84  ? 149.563 92.414  92.244  1.00 51.18  ? 158 LYS B CB  1 
ATOM   2984 C CG  . LYS B 1 84  ? 149.168 91.956  93.632  1.00 53.40  ? 158 LYS B CG  1 
ATOM   2985 C CD  . LYS B 1 84  ? 147.993 91.004  93.568  1.00 52.74  ? 158 LYS B CD  1 
ATOM   2986 C CE  . LYS B 1 84  ? 146.710 91.738  93.246  1.00 55.22  ? 158 LYS B CE  1 
ATOM   2987 N NZ  . LYS B 1 84  ? 145.552 90.813  93.302  1.00 57.45  ? 158 LYS B NZ  1 
ATOM   2988 N N   . LYS B 1 85  ? 152.693 91.813  91.933  1.00 55.47  ? 159 LYS B N   1 
ATOM   2989 C CA  . LYS B 1 85  ? 153.722 90.892  92.407  1.00 54.40  ? 159 LYS B CA  1 
ATOM   2990 C C   . LYS B 1 85  ? 154.928 91.588  93.029  1.00 54.53  ? 159 LYS B C   1 
ATOM   2991 O O   . LYS B 1 85  ? 155.873 90.896  93.423  1.00 55.94  ? 159 LYS B O   1 
ATOM   2992 C CB  . LYS B 1 85  ? 154.188 90.000  91.256  1.00 53.93  ? 159 LYS B CB  1 
ATOM   2993 C CG  . LYS B 1 85  ? 155.213 88.950  91.659  1.00 55.45  ? 159 LYS B CG  1 
ATOM   2994 C CD  . LYS B 1 85  ? 155.595 88.070  90.481  1.00 56.95  ? 159 LYS B CD  1 
ATOM   2995 C CE  . LYS B 1 85  ? 156.636 87.037  90.878  1.00 58.02  ? 159 LYS B CE  1 
ATOM   2996 N NZ  . LYS B 1 85  ? 157.020 86.166  89.732  1.00 52.94  ? 159 LYS B NZ  1 
ATOM   2997 N N   . LYS B 1 86  ? 154.930 92.917  93.132  1.00 43.78  ? 160 LYS B N   1 
ATOM   2998 C CA  . LYS B 1 86  ? 156.036 93.653  93.733  1.00 44.37  ? 160 LYS B CA  1 
ATOM   2999 C C   . LYS B 1 86  ? 155.607 94.361  95.015  1.00 49.73  ? 160 LYS B C   1 
ATOM   3000 O O   . LYS B 1 86  ? 156.098 95.448  95.327  1.00 51.93  ? 160 LYS B O   1 
ATOM   3001 C CB  . LYS B 1 86  ? 156.624 94.649  92.735  1.00 46.97  ? 160 LYS B CB  1 
ATOM   3002 C CG  . LYS B 1 86  ? 156.830 94.077  91.343  1.00 47.74  ? 160 LYS B CG  1 
ATOM   3003 C CD  . LYS B 1 86  ? 156.828 95.166  90.284  1.00 46.24  ? 160 LYS B CD  1 
ATOM   3004 C CE  . LYS B 1 86  ? 157.878 96.224  90.578  1.00 47.62  ? 160 LYS B CE  1 
ATOM   3005 N NZ  . LYS B 1 86  ? 157.875 97.309  89.558  1.00 46.64  ? 160 LYS B NZ  1 
ATOM   3006 N N   . PHE B 1 87  ? 154.691 93.756  95.765  1.00 42.05  ? 161 PHE B N   1 
ATOM   3007 C CA  . PHE B 1 87  ? 154.209 94.311  97.023  1.00 31.48  ? 161 PHE B CA  1 
ATOM   3008 C C   . PHE B 1 87  ? 154.978 93.693  98.183  1.00 39.29  ? 161 PHE B C   1 
ATOM   3009 O O   . PHE B 1 87  ? 155.082 92.466  98.280  1.00 50.14  ? 161 PHE B O   1 
ATOM   3010 C CB  . PHE B 1 87  ? 152.711 94.054  97.200  1.00 35.55  ? 161 PHE B CB  1 
ATOM   3011 C CG  . PHE B 1 87  ? 151.833 95.001  96.434  1.00 34.05  ? 161 PHE B CG  1 
ATOM   3012 C CD1 . PHE B 1 87  ? 152.166 96.336  96.319  1.00 41.68  ? 161 PHE B CD1 1 
ATOM   3013 C CD2 . PHE B 1 87  ? 150.665 94.557  95.843  1.00 41.35  ? 161 PHE B CD2 1 
ATOM   3014 C CE1 . PHE B 1 87  ? 151.357 97.210  95.618  1.00 41.63  ? 161 PHE B CE1 1 
ATOM   3015 C CE2 . PHE B 1 87  ? 149.851 95.425  95.143  1.00 41.05  ? 161 PHE B CE2 1 
ATOM   3016 C CZ  . PHE B 1 87  ? 150.198 96.754  95.031  1.00 40.08  ? 161 PHE B CZ  1 
ATOM   3017 N N   . THR B 1 88  ? 155.512 94.543  99.060  1.00 40.00  ? 162 THR B N   1 
ATOM   3018 C CA  . THR B 1 88  ? 156.157 94.081  100.291 1.00 38.75  ? 162 THR B CA  1 
ATOM   3019 C C   . THR B 1 88  ? 155.091 93.921  101.375 1.00 41.03  ? 162 THR B C   1 
ATOM   3020 O O   . THR B 1 88  ? 155.002 94.683  102.339 1.00 46.07  ? 162 THR B O   1 
ATOM   3021 C CB  . THR B 1 88  ? 157.254 95.061  100.746 1.00 45.30  ? 162 THR B CB  1 
ATOM   3022 O OG1 . THR B 1 88  ? 158.263 95.156  99.734  1.00 47.79  ? 162 THR B OG1 1 
ATOM   3023 C CG2 . THR B 1 88  ? 158.009 94.500  101.942 1.00 45.20  ? 162 THR B CG2 1 
ATOM   3024 N N   . THR B 1 89  ? 154.269 92.893  101.191 1.00 52.27  ? 163 THR B N   1 
ATOM   3025 C CA  . THR B 1 89  ? 153.085 92.712  102.018 1.00 52.79  ? 163 THR B CA  1 
ATOM   3026 C C   . THR B 1 89  ? 153.454 92.297  103.438 1.00 51.59  ? 163 THR B C   1 
ATOM   3027 O O   . THR B 1 89  ? 154.529 91.752  103.698 1.00 55.56  ? 163 THR B O   1 
ATOM   3028 C CB  . THR B 1 89  ? 152.155 91.667  101.399 1.00 54.72  ? 163 THR B CB  1 
ATOM   3029 O OG1 . THR B 1 89  ? 150.925 91.625  102.132 1.00 55.80  ? 163 THR B OG1 1 
ATOM   3030 C CG2 . THR B 1 89  ? 152.802 90.290  101.421 1.00 53.44  ? 163 THR B CG2 1 
ATOM   3031 N N   . PHE B 1 90  ? 152.540 92.579  104.364 1.00 62.78  ? 164 PHE B N   1 
ATOM   3032 C CA  . PHE B 1 90  ? 152.664 92.183  105.757 1.00 66.51  ? 164 PHE B CA  1 
ATOM   3033 C C   . PHE B 1 90  ? 151.297 91.755  106.273 1.00 66.94  ? 164 PHE B C   1 
ATOM   3034 O O   . PHE B 1 90  ? 150.264 92.265  105.832 1.00 63.36  ? 164 PHE B O   1 
ATOM   3035 C CB  . PHE B 1 90  ? 153.239 93.319  106.618 1.00 59.73  ? 164 PHE B CB  1 
ATOM   3036 C CG  . PHE B 1 90  ? 152.372 94.544  106.668 1.00 59.37  ? 164 PHE B CG  1 
ATOM   3037 C CD1 . PHE B 1 90  ? 152.500 95.536  105.710 1.00 62.01  ? 164 PHE B CD1 1 
ATOM   3038 C CD2 . PHE B 1 90  ? 151.437 94.711  107.676 1.00 61.28  ? 164 PHE B CD2 1 
ATOM   3039 C CE1 . PHE B 1 90  ? 151.709 96.667  105.753 1.00 63.34  ? 164 PHE B CE1 1 
ATOM   3040 C CE2 . PHE B 1 90  ? 150.646 95.840  107.725 1.00 63.13  ? 164 PHE B CE2 1 
ATOM   3041 C CZ  . PHE B 1 90  ? 150.780 96.819  106.762 1.00 63.99  ? 164 PHE B CZ  1 
ATOM   3042 N N   . ARG B 1 91  ? 151.301 90.821  107.221 1.00 76.05  ? 165 ARG B N   1 
ATOM   3043 C CA  . ARG B 1 91  ? 150.083 90.167  107.680 1.00 75.61  ? 165 ARG B CA  1 
ATOM   3044 C C   . ARG B 1 91  ? 149.538 90.753  108.976 1.00 75.02  ? 165 ARG B C   1 
ATOM   3045 O O   . ARG B 1 91  ? 148.661 90.140  109.593 1.00 76.47  ? 165 ARG B O   1 
ATOM   3046 C CB  . ARG B 1 91  ? 150.332 88.668  107.861 1.00 76.08  ? 165 ARG B CB  1 
ATOM   3047 C CG  . ARG B 1 91  ? 149.110 87.887  108.317 1.00 76.69  ? 165 ARG B CG  1 
ATOM   3048 C CD  . ARG B 1 91  ? 149.337 86.388  108.428 1.00 76.96  ? 165 ARG B CD  1 
ATOM   3049 N NE  . ARG B 1 91  ? 150.308 86.056  109.467 1.00 78.40  ? 165 ARG B NE  1 
ATOM   3050 C CZ  . ARG B 1 91  ? 150.014 85.949  110.754 1.00 79.06  ? 165 ARG B CZ  1 
ATOM   3051 N NH1 . ARG B 1 91  ? 148.769 86.143  111.171 1.00 77.18  ? 165 ARG B NH1 1 
ATOM   3052 N NH2 . ARG B 1 91  ? 150.962 85.644  111.631 1.00 78.29  ? 165 ARG B NH2 1 
ATOM   3053 N N   . SER B 1 98  ? 157.038 98.770  112.061 1.00 73.10  ? 172 SER B N   1 
ATOM   3054 C CA  . SER B 1 98  ? 157.902 99.840  112.532 1.00 72.79  ? 172 SER B CA  1 
ATOM   3055 C C   . SER B 1 98  ? 159.229 99.811  111.778 1.00 72.37  ? 172 SER B C   1 
ATOM   3056 O O   . SER B 1 98  ? 159.517 98.884  111.018 1.00 72.49  ? 172 SER B O   1 
ATOM   3057 C CB  . SER B 1 98  ? 158.142 99.714  114.036 1.00 75.95  ? 172 SER B CB  1 
ATOM   3058 O OG  . SER B 1 98  ? 158.975 100.760 114.507 1.00 77.49  ? 172 SER B OG  1 
ATOM   3059 N N   . ASN B 1 99  ? 159.996 100.894 111.942 1.00 71.90  ? 173 ASN B N   1 
ATOM   3060 C CA  . ASN B 1 99  ? 161.343 101.110 111.403 1.00 72.26  ? 173 ASN B CA  1 
ATOM   3061 C C   . ASN B 1 99  ? 161.529 100.543 109.998 1.00 75.72  ? 173 ASN B C   1 
ATOM   3062 O O   . ASN B 1 99  ? 162.603 100.028 109.672 1.00 78.20  ? 173 ASN B O   1 
ATOM   3063 C CB  . ASN B 1 99  ? 162.449 100.604 112.354 1.00 71.18  ? 173 ASN B CB  1 
ATOM   3064 C CG  . ASN B 1 99  ? 162.473 99.086  112.545 1.00 75.17  ? 173 ASN B CG  1 
ATOM   3065 O OD1 . ASN B 1 99  ? 161.784 98.331  111.871 1.00 75.53  ? 173 ASN B OD1 1 
ATOM   3066 N ND2 . ASN B 1 99  ? 163.292 98.641  113.490 1.00 73.94  ? 173 ASN B ND2 1 
ATOM   3067 N N   . GLN B 1 100 ? 160.501 100.635 109.154 1.00 65.03  ? 174 GLN B N   1 
ATOM   3068 C CA  . GLN B 1 100 ? 160.586 100.171 107.772 1.00 60.59  ? 174 GLN B CA  1 
ATOM   3069 C C   . GLN B 1 100 ? 159.926 101.094 106.760 1.00 60.35  ? 174 GLN B C   1 
ATOM   3070 O O   . GLN B 1 100 ? 160.162 100.916 105.560 1.00 60.00  ? 174 GLN B O   1 
ATOM   3071 C CB  . GLN B 1 100 ? 159.967 98.774  107.633 1.00 60.21  ? 174 GLN B CB  1 
ATOM   3072 C CG  . GLN B 1 100 ? 160.801 97.648  108.223 1.00 62.12  ? 174 GLN B CG  1 
ATOM   3073 C CD  . GLN B 1 100 ? 160.076 96.316  108.203 1.00 62.86  ? 174 GLN B CD  1 
ATOM   3074 O OE1 . GLN B 1 100 ? 158.933 96.226  107.756 1.00 63.29  ? 174 GLN B OE1 1 
ATOM   3075 N NE2 . GLN B 1 100 ? 160.741 95.273  108.685 1.00 63.29  ? 174 GLN B NE2 1 
ATOM   3076 N N   . ILE B 1 101 ? 159.118 102.065 107.177 1.00 52.51  ? 175 ILE B N   1 
ATOM   3077 C CA  . ILE B 1 101 ? 158.318 102.883 106.272 1.00 45.52  ? 175 ILE B CA  1 
ATOM   3078 C C   . ILE B 1 101 ? 158.798 104.324 106.361 1.00 44.95  ? 175 ILE B C   1 
ATOM   3079 O O   . ILE B 1 101 ? 158.894 104.887 107.458 1.00 51.78  ? 175 ILE B O   1 
ATOM   3080 C CB  . ILE B 1 101 ? 156.820 102.784 106.607 1.00 43.60  ? 175 ILE B CB  1 
ATOM   3081 C CG1 . ILE B 1 101 ? 156.343 101.337 106.488 1.00 45.88  ? 175 ILE B CG1 1 
ATOM   3082 C CG2 . ILE B 1 101 ? 156.009 103.690 105.696 1.00 48.10  ? 175 ILE B CG2 1 
ATOM   3083 C CD1 . ILE B 1 101 ? 156.566 100.737 105.123 1.00 48.69  ? 175 ILE B CD1 1 
ATOM   3084 N N   . ASP B 1 102 ? 159.087 104.925 105.205 1.00 33.25  ? 176 ASP B N   1 
ATOM   3085 C CA  . ASP B 1 102 ? 159.541 106.310 105.181 1.00 34.01  ? 176 ASP B CA  1 
ATOM   3086 C C   . ASP B 1 102 ? 158.375 107.282 105.329 1.00 43.49  ? 176 ASP B C   1 
ATOM   3087 O O   . ASP B 1 102 ? 158.454 108.241 106.104 1.00 50.19  ? 176 ASP B O   1 
ATOM   3088 C CB  . ASP B 1 102 ? 160.311 106.587 103.890 1.00 41.96  ? 176 ASP B CB  1 
ATOM   3089 C CG  . ASP B 1 102 ? 161.460 105.624 103.682 1.00 52.23  ? 176 ASP B CG  1 
ATOM   3090 O OD1 . ASP B 1 102 ? 162.389 105.617 104.516 1.00 53.50  ? 176 ASP B OD1 1 
ATOM   3091 O OD2 . ASP B 1 102 ? 161.433 104.868 102.688 1.00 53.99  ? 176 ASP B OD2 1 
ATOM   3092 N N   . PHE B 1 103 ? 157.290 107.055 104.592 1.00 34.44  ? 177 PHE B N   1 
ATOM   3093 C CA  . PHE B 1 103 ? 156.092 107.873 104.731 1.00 30.63  ? 177 PHE B CA  1 
ATOM   3094 C C   . PHE B 1 103 ? 154.893 107.080 104.233 1.00 29.04  ? 177 PHE B C   1 
ATOM   3095 O O   . PHE B 1 103 ? 155.037 106.072 103.538 1.00 40.59  ? 177 PHE B O   1 
ATOM   3096 C CB  . PHE B 1 103 ? 156.225 109.211 103.990 1.00 34.88  ? 177 PHE B CB  1 
ATOM   3097 C CG  . PHE B 1 103 ? 156.022 109.117 102.506 1.00 28.11  ? 177 PHE B CG  1 
ATOM   3098 C CD1 . PHE B 1 103 ? 156.982 108.536 101.697 1.00 35.97  ? 177 PHE B CD1 1 
ATOM   3099 C CD2 . PHE B 1 103 ? 154.883 109.637 101.917 1.00 32.47  ? 177 PHE B CD2 1 
ATOM   3100 C CE1 . PHE B 1 103 ? 156.801 108.459 100.332 1.00 33.82  ? 177 PHE B CE1 1 
ATOM   3101 C CE2 . PHE B 1 103 ? 154.697 109.563 100.553 1.00 34.24  ? 177 PHE B CE2 1 
ATOM   3102 C CZ  . PHE B 1 103 ? 155.657 108.972 99.759  1.00 34.61  ? 177 PHE B CZ  1 
ATOM   3103 N N   . ILE B 1 104 ? 153.705 107.550 104.608 1.00 29.45  ? 178 ILE B N   1 
ATOM   3104 C CA  . ILE B 1 104 ? 152.458 106.826 104.400 1.00 20.38  ? 178 ILE B CA  1 
ATOM   3105 C C   . ILE B 1 104 ? 151.545 107.645 103.499 1.00 26.58  ? 178 ILE B C   1 
ATOM   3106 O O   . ILE B 1 104 ? 151.443 108.868 103.648 1.00 38.04  ? 178 ILE B O   1 
ATOM   3107 C CB  . ILE B 1 104 ? 151.759 106.520 105.740 1.00 21.96  ? 178 ILE B CB  1 
ATOM   3108 C CG1 . ILE B 1 104 ? 152.662 105.674 106.634 1.00 30.72  ? 178 ILE B CG1 1 
ATOM   3109 C CG2 . ILE B 1 104 ? 150.437 105.805 105.514 1.00 29.74  ? 178 ILE B CG2 1 
ATOM   3110 C CD1 . ILE B 1 104 ? 152.199 105.621 108.066 1.00 33.97  ? 178 ILE B CD1 1 
ATOM   3111 N N   . ILE B 1 105 ? 150.888 106.969 102.560 1.00 21.60  ? 179 ILE B N   1 
ATOM   3112 C CA  . ILE B 1 105 ? 149.831 107.554 101.743 1.00 19.64  ? 179 ILE B CA  1 
ATOM   3113 C C   . ILE B 1 105 ? 148.523 106.875 102.121 1.00 24.44  ? 179 ILE B C   1 
ATOM   3114 O O   . ILE B 1 105 ? 148.425 105.643 102.086 1.00 34.90  ? 179 ILE B O   1 
ATOM   3115 C CB  . ILE B 1 105 ? 150.120 107.399 100.241 1.00 13.91  ? 179 ILE B CB  1 
ATOM   3116 C CG1 . ILE B 1 105 ? 151.515 107.927 99.907  1.00 23.55  ? 179 ILE B CG1 1 
ATOM   3117 C CG2 . ILE B 1 105 ? 149.065 108.120 99.423  1.00 22.35  ? 179 ILE B CG2 1 
ATOM   3118 C CD1 . ILE B 1 105 ? 151.851 107.868 98.436  1.00 23.70  ? 179 ILE B CD1 1 
ATOM   3119 N N   . CYS B 1 106 ? 147.523 107.672 102.481 1.00 31.04  ? 180 CYS B N   1 
ATOM   3120 C CA  . CYS B 1 106 ? 146.252 107.164 102.976 1.00 26.94  ? 180 CYS B CA  1 
ATOM   3121 C C   . CYS B 1 106 ? 145.132 107.480 101.994 1.00 34.41  ? 180 CYS B C   1 
ATOM   3122 O O   . CYS B 1 106 ? 145.054 108.591 101.462 1.00 38.91  ? 180 CYS B O   1 
ATOM   3123 C CB  . CYS B 1 106 ? 145.922 107.758 104.348 1.00 29.96  ? 180 CYS B CB  1 
ATOM   3124 S SG  . CYS B 1 106 ? 146.799 106.983 105.723 1.00 49.05  ? 180 CYS B SG  1 
ATOM   3125 N N   . LEU B 1 107 ? 144.271 106.492 101.758 1.00 32.73  ? 181 LEU B N   1 
ATOM   3126 C CA  . LEU B 1 107 ? 143.123 106.633 100.872 1.00 24.66  ? 181 LEU B CA  1 
ATOM   3127 C C   . LEU B 1 107 ? 141.866 106.200 101.610 1.00 32.72  ? 181 LEU B C   1 
ATOM   3128 O O   . LEU B 1 107 ? 141.838 105.120 102.208 1.00 42.06  ? 181 LEU B O   1 
ATOM   3129 C CB  . LEU B 1 107 ? 143.296 105.789 99.604  1.00 24.18  ? 181 LEU B CB  1 
ATOM   3130 C CG  . LEU B 1 107 ? 144.546 106.018 98.754  1.00 26.33  ? 181 LEU B CG  1 
ATOM   3131 C CD1 . LEU B 1 107 ? 144.844 104.790 97.915  1.00 27.29  ? 181 LEU B CD1 1 
ATOM   3132 C CD2 . LEU B 1 107 ? 144.371 107.236 97.868  1.00 34.95  ? 181 LEU B CD2 1 
ATOM   3133 N N   . GLY B 1 108 ? 140.832 107.038 101.570 1.00 38.18  ? 182 GLY B N   1 
ATOM   3134 C CA  . GLY B 1 108 ? 139.530 106.620 102.051 1.00 43.12  ? 182 GLY B CA  1 
ATOM   3135 C C   . GLY B 1 108 ? 138.777 107.601 102.927 1.00 41.81  ? 182 GLY B C   1 
ATOM   3136 O O   . GLY B 1 108 ? 137.549 107.686 102.836 1.00 52.36  ? 182 GLY B O   1 
ATOM   3137 N N   . GLY B 1 109 ? 139.477 108.347 103.768 1.00 27.92  ? 183 GLY B N   1 
ATOM   3138 C CA  . GLY B 1 109 ? 138.819 109.296 104.635 1.00 35.57  ? 183 GLY B CA  1 
ATOM   3139 C C   . GLY B 1 109 ? 139.505 109.373 105.981 1.00 37.56  ? 183 GLY B C   1 
ATOM   3140 O O   . GLY B 1 109 ? 140.633 108.913 106.148 1.00 45.59  ? 183 GLY B O   1 
ATOM   3141 N N   . ASP B 1 110 ? 138.796 109.972 106.942 1.00 33.01  ? 184 ASP B N   1 
ATOM   3142 C CA  . ASP B 1 110 ? 139.376 110.226 108.257 1.00 29.24  ? 184 ASP B CA  1 
ATOM   3143 C C   . ASP B 1 110 ? 139.685 108.931 108.997 1.00 34.10  ? 184 ASP B C   1 
ATOM   3144 O O   . ASP B 1 110 ? 140.758 108.795 109.597 1.00 40.39  ? 184 ASP B O   1 
ATOM   3145 C CB  . ASP B 1 110 ? 138.429 111.094 109.084 1.00 37.73  ? 184 ASP B CB  1 
ATOM   3146 C CG  . ASP B 1 110 ? 138.513 112.560 108.719 1.00 42.50  ? 184 ASP B CG  1 
ATOM   3147 O OD1 . ASP B 1 110 ? 139.630 113.042 108.443 1.00 41.87  ? 184 ASP B OD1 1 
ATOM   3148 O OD2 . ASP B 1 110 ? 137.461 113.233 108.708 1.00 44.95  ? 184 ASP B OD2 1 
ATOM   3149 N N   . GLY B 1 111 ? 138.763 107.966 108.956 1.00 35.93  ? 185 GLY B N   1 
ATOM   3150 C CA  . GLY B 1 111 ? 138.941 106.746 109.726 1.00 31.23  ? 185 GLY B CA  1 
ATOM   3151 C C   . GLY B 1 111 ? 140.174 105.959 109.332 1.00 32.02  ? 185 GLY B C   1 
ATOM   3152 O O   . GLY B 1 111 ? 140.701 105.182 110.132 1.00 34.04  ? 185 GLY B O   1 
ATOM   3153 N N   . THR B 1 112 ? 140.647 106.141 108.098 1.00 29.81  ? 186 THR B N   1 
ATOM   3154 C CA  . THR B 1 112 ? 141.896 105.510 107.688 1.00 28.22  ? 186 THR B CA  1 
ATOM   3155 C C   . THR B 1 112 ? 143.072 106.052 108.490 1.00 35.55  ? 186 THR B C   1 
ATOM   3156 O O   . THR B 1 112 ? 143.904 105.280 108.985 1.00 43.93  ? 186 THR B O   1 
ATOM   3157 C CB  . THR B 1 112 ? 142.120 105.718 106.190 1.00 34.68  ? 186 THR B CB  1 
ATOM   3158 O OG1 . THR B 1 112 ? 141.254 104.848 105.450 1.00 40.62  ? 186 THR B OG1 1 
ATOM   3159 C CG2 . THR B 1 112 ? 143.558 105.422 105.816 1.00 36.88  ? 186 THR B CG2 1 
ATOM   3160 N N   . LEU B 1 113 ? 143.135 107.376 108.663 1.00 34.87  ? 187 LEU B N   1 
ATOM   3161 C CA  . LEU B 1 113 ? 144.255 107.985 109.376 1.00 27.41  ? 187 LEU B CA  1 
ATOM   3162 C C   . LEU B 1 113 ? 144.367 107.437 110.791 1.00 30.85  ? 187 LEU B C   1 
ATOM   3163 O O   . LEU B 1 113 ? 145.461 107.079 111.247 1.00 38.02  ? 187 LEU B O   1 
ATOM   3164 C CB  . LEU B 1 113 ? 144.096 109.504 109.401 1.00 27.08  ? 187 LEU B CB  1 
ATOM   3165 C CG  . LEU B 1 113 ? 145.333 110.274 109.862 1.00 35.65  ? 187 LEU B CG  1 
ATOM   3166 C CD1 . LEU B 1 113 ? 146.500 109.978 108.955 1.00 38.44  ? 187 LEU B CD1 1 
ATOM   3167 C CD2 . LEU B 1 113 ? 145.063 111.765 109.909 1.00 37.07  ? 187 LEU B CD2 1 
ATOM   3168 N N   . LEU B 1 114 ? 143.236 107.348 111.494 1.00 31.39  ? 188 LEU B N   1 
ATOM   3169 C CA  . LEU B 1 114 ? 143.221 106.739 112.819 1.00 33.73  ? 188 LEU B CA  1 
ATOM   3170 C C   . LEU B 1 114 ? 143.836 105.348 112.777 1.00 30.61  ? 188 LEU B C   1 
ATOM   3171 O O   . LEU B 1 114 ? 144.693 105.006 113.601 1.00 38.72  ? 188 LEU B O   1 
ATOM   3172 C CB  . LEU B 1 114 ? 141.787 106.677 113.349 1.00 33.78  ? 188 LEU B CB  1 
ATOM   3173 C CG  . LEU B 1 114 ? 141.155 107.938 113.945 1.00 26.19  ? 188 LEU B CG  1 
ATOM   3174 C CD1 . LEU B 1 114 ? 140.859 108.972 112.870 1.00 34.07  ? 188 LEU B CD1 1 
ATOM   3175 C CD2 . LEU B 1 114 ? 139.887 107.576 114.695 1.00 33.50  ? 188 LEU B CD2 1 
ATOM   3176 N N   . TYR B 1 115 ? 143.434 104.546 111.786 1.00 27.66  ? 189 TYR B N   1 
ATOM   3177 C CA  . TYR B 1 115 ? 143.980 103.201 111.655 1.00 26.60  ? 189 TYR B CA  1 
ATOM   3178 C C   . TYR B 1 115 ? 145.492 103.241 111.491 1.00 25.64  ? 189 TYR B C   1 
ATOM   3179 O O   . TYR B 1 115 ? 146.206 102.394 112.042 1.00 32.82  ? 189 TYR B O   1 
ATOM   3180 C CB  . TYR B 1 115 ? 143.323 102.483 110.476 1.00 32.49  ? 189 TYR B CB  1 
ATOM   3181 C CG  . TYR B 1 115 ? 143.939 101.143 110.146 1.00 26.61  ? 189 TYR B CG  1 
ATOM   3182 C CD1 . TYR B 1 115 ? 143.713 100.037 110.953 1.00 29.56  ? 189 TYR B CD1 1 
ATOM   3183 C CD2 . TYR B 1 115 ? 144.737 100.982 109.023 1.00 27.13  ? 189 TYR B CD2 1 
ATOM   3184 C CE1 . TYR B 1 115 ? 144.270 98.811  110.655 1.00 30.67  ? 189 TYR B CE1 1 
ATOM   3185 C CE2 . TYR B 1 115 ? 145.298 99.759  108.715 1.00 31.53  ? 189 TYR B CE2 1 
ATOM   3186 C CZ  . TYR B 1 115 ? 145.061 98.677  109.535 1.00 31.29  ? 189 TYR B CZ  1 
ATOM   3187 O OH  . TYR B 1 115 ? 145.619 97.457  109.233 1.00 37.69  ? 189 TYR B OH  1 
ATOM   3188 N N   . ALA B 1 116 ? 146.002 104.236 110.759 1.00 27.12  ? 190 ALA B N   1 
ATOM   3189 C CA  . ALA B 1 116 ? 147.446 104.385 110.634 1.00 26.82  ? 190 ALA B CA  1 
ATOM   3190 C C   . ALA B 1 116 ? 148.089 104.577 111.999 1.00 30.84  ? 190 ALA B C   1 
ATOM   3191 O O   . ALA B 1 116 ? 149.091 103.925 112.321 1.00 40.12  ? 190 ALA B O   1 
ATOM   3192 C CB  . ALA B 1 116 ? 147.778 105.557 109.711 1.00 29.85  ? 190 ALA B CB  1 
ATOM   3193 N N   . SER B 1 117 ? 147.501 105.440 112.834 1.00 23.35  ? 191 SER B N   1 
ATOM   3194 C CA  . SER B 1 117 ? 148.016 105.628 114.184 1.00 26.86  ? 191 SER B CA  1 
ATOM   3195 C C   . SER B 1 117 ? 147.956 104.343 114.994 1.00 33.96  ? 191 SER B C   1 
ATOM   3196 O O   . SER B 1 117 ? 148.745 104.174 115.930 1.00 37.96  ? 191 SER B O   1 
ATOM   3197 C CB  . SER B 1 117 ? 147.239 106.735 114.896 1.00 34.17  ? 191 SER B CB  1 
ATOM   3198 O OG  . SER B 1 117 ? 147.363 106.623 116.302 1.00 39.89  ? 191 SER B OG  1 
ATOM   3199 N N   . SER B 1 118 ? 147.038 103.434 114.654 1.00 31.15  ? 192 SER B N   1 
ATOM   3200 C CA  . SER B 1 118 ? 146.992 102.148 115.337 1.00 26.04  ? 192 SER B CA  1 
ATOM   3201 C C   . SER B 1 118 ? 148.189 101.279 114.976 1.00 30.89  ? 192 SER B C   1 
ATOM   3202 O O   . SER B 1 118 ? 148.671 100.512 115.817 1.00 37.96  ? 192 SER B O   1 
ATOM   3203 C CB  . SER B 1 118 ? 145.689 101.423 115.005 1.00 31.29  ? 192 SER B CB  1 
ATOM   3204 O OG  . SER B 1 118 ? 144.569 102.140 115.494 1.00 38.40  ? 192 SER B OG  1 
ATOM   3205 N N   . LEU B 1 119 ? 148.681 101.381 113.739 1.00 32.14  ? 193 LEU B N   1 
ATOM   3206 C CA  . LEU B 1 119 ? 149.774 100.520 113.306 1.00 28.91  ? 193 LEU B CA  1 
ATOM   3207 C C   . LEU B 1 119 ? 151.128 100.959 113.844 1.00 30.74  ? 193 LEU B C   1 
ATOM   3208 O O   . LEU B 1 119 ? 152.045 100.135 113.918 1.00 38.16  ? 193 LEU B O   1 
ATOM   3209 C CB  . LEU B 1 119 ? 149.829 100.462 111.778 1.00 27.56  ? 193 LEU B CB  1 
ATOM   3210 C CG  . LEU B 1 119 ? 148.526 100.147 111.046 1.00 28.43  ? 193 LEU B CG  1 
ATOM   3211 C CD1 . LEU B 1 119 ? 148.688 100.385 109.556 1.00 32.78  ? 193 LEU B CD1 1 
ATOM   3212 C CD2 . LEU B 1 119 ? 148.098 98.716  111.320 1.00 34.73  ? 193 LEU B CD2 1 
ATOM   3213 N N   . PHE B 1 120 ? 151.274 102.225 114.223 1.00 29.00  ? 194 PHE B N   1 
ATOM   3214 C CA  . PHE B 1 120 ? 152.546 102.776 114.683 1.00 32.55  ? 194 PHE B CA  1 
ATOM   3215 C C   . PHE B 1 120 ? 152.365 103.267 116.116 1.00 36.39  ? 194 PHE B C   1 
ATOM   3216 O O   . PHE B 1 120 ? 152.028 104.430 116.351 1.00 41.33  ? 194 PHE B O   1 
ATOM   3217 C CB  . PHE B 1 120 ? 153.017 103.890 113.756 1.00 31.90  ? 194 PHE B CB  1 
ATOM   3218 C CG  . PHE B 1 120 ? 153.482 103.401 112.416 1.00 31.29  ? 194 PHE B CG  1 
ATOM   3219 C CD1 . PHE B 1 120 ? 154.762 102.902 112.254 1.00 37.62  ? 194 PHE B CD1 1 
ATOM   3220 C CD2 . PHE B 1 120 ? 152.634 103.422 111.324 1.00 31.56  ? 194 PHE B CD2 1 
ATOM   3221 C CE1 . PHE B 1 120 ? 155.191 102.446 111.024 1.00 39.78  ? 194 PHE B CE1 1 
ATOM   3222 C CE2 . PHE B 1 120 ? 153.057 102.963 110.094 1.00 32.54  ? 194 PHE B CE2 1 
ATOM   3223 C CZ  . PHE B 1 120 ? 154.337 102.477 109.943 1.00 39.17  ? 194 PHE B CZ  1 
ATOM   3224 N N   . GLN B 1 121 ? 152.592 102.370 117.075 1.00 35.18  ? 195 GLN B N   1 
ATOM   3225 C CA  . GLN B 1 121 ? 152.500 102.719 118.485 1.00 35.99  ? 195 GLN B CA  1 
ATOM   3226 C C   . GLN B 1 121 ? 153.691 103.535 118.966 1.00 37.38  ? 195 GLN B C   1 
ATOM   3227 O O   . GLN B 1 121 ? 153.652 104.059 120.084 1.00 38.67  ? 195 GLN B O   1 
ATOM   3228 C CB  . GLN B 1 121 ? 152.366 101.449 119.328 1.00 34.45  ? 195 GLN B CB  1 
ATOM   3229 C CG  . GLN B 1 121 ? 151.093 100.663 119.054 1.00 39.75  ? 195 GLN B CG  1 
ATOM   3230 C CD  . GLN B 1 121 ? 149.841 101.410 119.467 1.00 39.49  ? 195 GLN B CD  1 
ATOM   3231 O OE1 . GLN B 1 121 ? 149.817 102.084 120.496 1.00 42.15  ? 195 GLN B OE1 1 
ATOM   3232 N NE2 . GLN B 1 121 ? 148.792 101.299 118.661 1.00 36.39  ? 195 GLN B NE2 1 
ATOM   3233 N N   . GLY B 1 122 ? 154.739 103.653 118.155 1.00 39.01  ? 196 GLY B N   1 
ATOM   3234 C CA  . GLY B 1 122 ? 155.878 104.485 118.486 1.00 32.98  ? 196 GLY B CA  1 
ATOM   3235 C C   . GLY B 1 122 ? 156.013 105.655 117.535 1.00 35.79  ? 196 GLY B C   1 
ATOM   3236 O O   . GLY B 1 122 ? 155.050 106.396 117.319 1.00 41.95  ? 196 GLY B O   1 
ATOM   3237 N N   . SER B 1 123 ? 157.198 105.831 116.957 1.00 34.79  ? 197 SER B N   1 
ATOM   3238 C CA  . SER B 1 123 ? 157.407 106.911 116.004 1.00 35.14  ? 197 SER B CA  1 
ATOM   3239 C C   . SER B 1 123 ? 156.595 106.666 114.738 1.00 39.85  ? 197 SER B C   1 
ATOM   3240 O O   . SER B 1 123 ? 156.543 105.547 114.219 1.00 44.96  ? 197 SER B O   1 
ATOM   3241 C CB  . SER B 1 123 ? 158.890 107.043 115.664 1.00 41.43  ? 197 SER B CB  1 
ATOM   3242 O OG  . SER B 1 123 ? 159.106 108.077 114.720 1.00 46.11  ? 197 SER B OG  1 
ATOM   3243 N N   . VAL B 1 124 ? 155.959 107.719 114.243 1.00 37.13  ? 198 VAL B N   1 
ATOM   3244 C CA  . VAL B 1 124 ? 155.042 107.646 113.111 1.00 31.78  ? 198 VAL B CA  1 
ATOM   3245 C C   . VAL B 1 124 ? 155.667 108.400 111.943 1.00 35.53  ? 198 VAL B C   1 
ATOM   3246 O O   . VAL B 1 124 ? 156.000 109.584 112.086 1.00 37.49  ? 198 VAL B O   1 
ATOM   3247 C CB  . VAL B 1 124 ? 153.661 108.223 113.461 1.00 28.61  ? 198 VAL B CB  1 
ATOM   3248 C CG1 . VAL B 1 124 ? 152.750 108.195 112.245 1.00 33.59  ? 198 VAL B CG1 1 
ATOM   3249 C CG2 . VAL B 1 124 ? 153.043 107.458 114.617 1.00 33.55  ? 198 VAL B CG2 1 
ATOM   3250 N N   . PRO B 1 125 ? 155.852 107.769 110.787 1.00 36.48  ? 199 PRO B N   1 
ATOM   3251 C CA  . PRO B 1 125 ? 156.339 108.492 109.612 1.00 32.19  ? 199 PRO B CA  1 
ATOM   3252 C C   . PRO B 1 125 ? 155.283 109.451 109.093 1.00 39.33  ? 199 PRO B C   1 
ATOM   3253 O O   . PRO B 1 125 ? 154.091 109.293 109.398 1.00 46.31  ? 199 PRO B O   1 
ATOM   3254 C CB  . PRO B 1 125 ? 156.622 107.368 108.605 1.00 31.04  ? 199 PRO B CB  1 
ATOM   3255 C CG  . PRO B 1 125 ? 155.699 106.279 109.011 1.00 30.93  ? 199 PRO B CG  1 
ATOM   3256 C CD  . PRO B 1 125 ? 155.665 106.335 110.510 1.00 35.25  ? 199 PRO B CD  1 
ATOM   3257 N N   . PRO B 1 126 ? 155.678 110.465 108.322 1.00 23.66  ? 200 PRO B N   1 
ATOM   3258 C CA  . PRO B 1 126 ? 154.694 111.427 107.811 1.00 26.95  ? 200 PRO B CA  1 
ATOM   3259 C C   . PRO B 1 126 ? 153.652 110.747 106.936 1.00 29.47  ? 200 PRO B C   1 
ATOM   3260 O O   . PRO B 1 126 ? 153.930 109.765 106.246 1.00 39.32  ? 200 PRO B O   1 
ATOM   3261 C CB  . PRO B 1 126 ? 155.542 112.418 107.003 1.00 31.00  ? 200 PRO B CB  1 
ATOM   3262 C CG  . PRO B 1 126 ? 156.859 111.753 106.799 1.00 34.03  ? 200 PRO B CG  1 
ATOM   3263 C CD  . PRO B 1 126 ? 157.055 110.823 107.947 1.00 25.24  ? 200 PRO B CD  1 
ATOM   3264 N N   . VAL B 1 127 ? 152.435 111.282 106.977 1.00 23.61  ? 201 VAL B N   1 
ATOM   3265 C CA  . VAL B 1 127 ? 151.288 110.689 106.301 1.00 22.02  ? 201 VAL B CA  1 
ATOM   3266 C C   . VAL B 1 127 ? 150.725 111.697 105.310 1.00 28.82  ? 201 VAL B C   1 
ATOM   3267 O O   . VAL B 1 127 ? 150.545 112.873 105.647 1.00 31.29  ? 201 VAL B O   1 
ATOM   3268 C CB  . VAL B 1 127 ? 150.205 110.247 107.301 1.00 18.51  ? 201 VAL B CB  1 
ATOM   3269 C CG1 . VAL B 1 127 ? 149.024 109.655 106.557 1.00 29.70  ? 201 VAL B CG1 1 
ATOM   3270 C CG2 . VAL B 1 127 ? 150.773 109.252 108.298 1.00 30.00  ? 201 VAL B CG2 1 
ATOM   3271 N N   . MET B 1 128 ? 150.450 111.235 104.094 1.00 27.78  ? 202 MET B N   1 
ATOM   3272 C CA  . MET B 1 128 ? 149.846 112.040 103.036 1.00 18.36  ? 202 MET B CA  1 
ATOM   3273 C C   . MET B 1 128 ? 148.451 111.474 102.777 1.00 25.39  ? 202 MET B C   1 
ATOM   3274 O O   . MET B 1 128 ? 148.280 110.540 101.993 1.00 36.42  ? 202 MET B O   1 
ATOM   3275 C CB  . MET B 1 128 ? 150.707 112.018 101.778 1.00 18.69  ? 202 MET B CB  1 
ATOM   3276 C CG  . MET B 1 128 ? 150.208 112.912 100.662 1.00 25.62  ? 202 MET B CG  1 
ATOM   3277 S SD  . MET B 1 128 ? 151.331 112.915 99.255  1.00 30.63  ? 202 MET B SD  1 
ATOM   3278 C CE  . MET B 1 128 ? 150.474 114.021 98.142  1.00 29.62  ? 202 MET B CE  1 
ATOM   3279 N N   . ALA B 1 129 ? 147.454 112.047 103.444 1.00 22.51  ? 203 ALA B N   1 
ATOM   3280 C CA  . ALA B 1 129 ? 146.095 111.530 103.370 1.00 19.34  ? 203 ALA B CA  1 
ATOM   3281 C C   . ALA B 1 129 ? 145.368 112.067 102.144 1.00 28.45  ? 203 ALA B C   1 
ATOM   3282 O O   . ALA B 1 129 ? 145.443 113.257 101.829 1.00 35.71  ? 203 ALA B O   1 
ATOM   3283 C CB  . ALA B 1 129 ? 145.318 111.893 104.636 1.00 29.26  ? 203 ALA B CB  1 
ATOM   3284 N N   . PHE B 1 130 ? 144.657 111.176 101.456 1.00 31.57  ? 204 PHE B N   1 
ATOM   3285 C CA  . PHE B 1 130 ? 143.869 111.515 100.280 1.00 19.75  ? 204 PHE B CA  1 
ATOM   3286 C C   . PHE B 1 130 ? 142.394 111.290 100.577 1.00 23.88  ? 204 PHE B C   1 
ATOM   3287 O O   . PHE B 1 130 ? 142.028 110.311 101.234 1.00 35.39  ? 204 PHE B O   1 
ATOM   3288 C CB  . PHE B 1 130 ? 144.283 110.672 99.070  1.00 20.84  ? 204 PHE B CB  1 
ATOM   3289 C CG  . PHE B 1 130 ? 145.451 111.228 98.310  1.00 15.76  ? 204 PHE B CG  1 
ATOM   3290 C CD1 . PHE B 1 130 ? 145.292 112.305 97.458  1.00 21.47  ? 204 PHE B CD1 1 
ATOM   3291 C CD2 . PHE B 1 130 ? 146.708 110.666 98.441  1.00 18.17  ? 204 PHE B CD2 1 
ATOM   3292 C CE1 . PHE B 1 130 ? 146.366 112.814 96.757  1.00 21.94  ? 204 PHE B CE1 1 
ATOM   3293 C CE2 . PHE B 1 130 ? 147.783 111.171 97.743  1.00 17.56  ? 204 PHE B CE2 1 
ATOM   3294 C CZ  . PHE B 1 130 ? 147.612 112.246 96.900  1.00 17.69  ? 204 PHE B CZ  1 
ATOM   3295 N N   . HIS B 1 131 ? 141.548 112.197 100.093 1.00 30.85  ? 205 HIS B N   1 
ATOM   3296 C CA  . HIS B 1 131 ? 140.102 112.092 100.264 1.00 29.23  ? 205 HIS B CA  1 
ATOM   3297 C C   . HIS B 1 131 ? 139.487 111.646 98.941  1.00 39.79  ? 205 HIS B C   1 
ATOM   3298 O O   . HIS B 1 131 ? 139.430 112.419 97.978  1.00 46.50  ? 205 HIS B O   1 
ATOM   3299 C CB  . HIS B 1 131 ? 139.506 113.413 100.754 1.00 25.16  ? 205 HIS B CB  1 
ATOM   3300 C CG  . HIS B 1 131 ? 139.738 114.573 99.835  1.00 29.87  ? 205 HIS B CG  1 
ATOM   3301 N ND1 . HIS B 1 131 ? 139.008 114.767 98.683  1.00 36.47  ? 205 HIS B ND1 1 
ATOM   3302 C CD2 . HIS B 1 131 ? 140.608 115.607 99.908  1.00 34.52  ? 205 HIS B CD2 1 
ATOM   3303 C CE1 . HIS B 1 131 ? 139.424 115.867 98.080  1.00 33.66  ? 205 HIS B CE1 1 
ATOM   3304 N NE2 . HIS B 1 131 ? 140.395 116.395 98.803  1.00 35.73  ? 205 HIS B NE2 1 
ATOM   3305 N N   . LEU B 1 132 ? 139.043 110.393 98.894  1.00 36.00  ? 206 LEU B N   1 
ATOM   3306 C CA  . LEU B 1 132 ? 138.410 109.814 97.715  1.00 31.12  ? 206 LEU B CA  1 
ATOM   3307 C C   . LEU B 1 132 ? 136.976 109.447 98.066  1.00 43.39  ? 206 LEU B C   1 
ATOM   3308 O O   . LEU B 1 132 ? 136.745 108.604 98.939  1.00 45.44  ? 206 LEU B O   1 
ATOM   3309 C CB  . LEU B 1 132 ? 139.173 108.581 97.227  1.00 30.72  ? 206 LEU B CB  1 
ATOM   3310 C CG  . LEU B 1 132 ? 140.344 108.758 96.258  1.00 32.32  ? 206 LEU B CG  1 
ATOM   3311 C CD1 . LEU B 1 132 ? 139.854 109.336 94.939  1.00 40.52  ? 206 LEU B CD1 1 
ATOM   3312 C CD2 . LEU B 1 132 ? 141.447 109.616 96.858  1.00 38.75  ? 206 LEU B CD2 1 
ATOM   3313 N N   . GLY B 1 133 ? 136.019 110.076 97.387  1.00 52.26  ? 207 GLY B N   1 
ATOM   3314 C CA  . GLY B 1 133 ? 134.620 109.819 97.662  1.00 54.34  ? 207 GLY B CA  1 
ATOM   3315 C C   . GLY B 1 133 ? 134.120 110.356 98.982  1.00 54.53  ? 207 GLY B C   1 
ATOM   3316 O O   . GLY B 1 133 ? 132.969 110.097 99.345  1.00 54.48  ? 207 GLY B O   1 
ATOM   3317 N N   . SER B 1 134 ? 134.950 111.097 99.711  1.00 51.11  ? 208 SER B N   1 
ATOM   3318 C CA  . SER B 1 134 ? 134.565 111.690 100.981 1.00 49.51  ? 208 SER B CA  1 
ATOM   3319 C C   . SER B 1 134 ? 135.270 113.029 101.116 1.00 47.36  ? 208 SER B C   1 
ATOM   3320 O O   . SER B 1 134 ? 136.322 113.253 100.511 1.00 48.83  ? 208 SER B O   1 
ATOM   3321 C CB  . SER B 1 134 ? 134.915 110.778 102.163 1.00 47.27  ? 208 SER B CB  1 
ATOM   3322 O OG  . SER B 1 134 ? 134.563 111.383 103.395 1.00 48.07  ? 208 SER B OG  1 
ATOM   3323 N N   . LEU B 1 135 ? 134.682 113.922 101.911 1.00 39.63  ? 209 LEU B N   1 
ATOM   3324 C CA  . LEU B 1 135 ? 135.265 115.250 102.065 1.00 40.80  ? 209 LEU B CA  1 
ATOM   3325 C C   . LEU B 1 135 ? 136.391 115.223 103.094 1.00 46.86  ? 209 LEU B C   1 
ATOM   3326 O O   . LEU B 1 135 ? 137.544 115.539 102.779 1.00 49.34  ? 209 LEU B O   1 
ATOM   3327 C CB  . LEU B 1 135 ? 134.177 116.258 102.448 1.00 44.35  ? 209 LEU B CB  1 
ATOM   3328 C CG  . LEU B 1 135 ? 134.474 117.746 102.232 1.00 45.66  ? 209 LEU B CG  1 
ATOM   3329 C CD1 . LEU B 1 135 ? 133.177 118.508 101.988 1.00 47.03  ? 209 LEU B CD1 1 
ATOM   3330 C CD2 . LEU B 1 135 ? 135.236 118.358 103.389 1.00 43.56  ? 209 LEU B CD2 1 
ATOM   3331 N N   . GLY B 1 136 ? 136.074 114.846 104.331 1.00 37.66  ? 210 GLY B N   1 
ATOM   3332 C CA  . GLY B 1 136 ? 137.089 114.585 105.334 1.00 34.76  ? 210 GLY B CA  1 
ATOM   3333 C C   . GLY B 1 136 ? 137.720 115.813 105.958 1.00 36.74  ? 210 GLY B C   1 
ATOM   3334 O O   . GLY B 1 136 ? 137.928 116.827 105.286 1.00 44.13  ? 210 GLY B O   1 
ATOM   3335 N N   . PHE B 1 137 ? 138.036 115.726 107.250 1.00 30.93  ? 211 PHE B N   1 
ATOM   3336 C CA  . PHE B 1 137 ? 138.709 116.803 107.966 1.00 29.21  ? 211 PHE B CA  1 
ATOM   3337 C C   . PHE B 1 137 ? 140.226 116.656 107.926 1.00 38.03  ? 211 PHE B C   1 
ATOM   3338 O O   . PHE B 1 137 ? 140.941 117.629 107.670 1.00 38.80  ? 211 PHE B O   1 
ATOM   3339 C CB  . PHE B 1 137 ? 138.222 116.851 109.418 1.00 31.58  ? 211 PHE B CB  1 
ATOM   3340 C CG  . PHE B 1 137 ? 138.339 118.207 110.053 1.00 32.19  ? 211 PHE B CG  1 
ATOM   3341 C CD1 . PHE B 1 137 ? 139.560 118.663 110.521 1.00 33.69  ? 211 PHE B CD1 1 
ATOM   3342 C CD2 . PHE B 1 137 ? 137.230 119.023 110.189 1.00 28.79  ? 211 PHE B CD2 1 
ATOM   3343 C CE1 . PHE B 1 137 ? 139.674 119.908 111.105 1.00 33.77  ? 211 PHE B CE1 1 
ATOM   3344 C CE2 . PHE B 1 137 ? 137.338 120.269 110.774 1.00 34.28  ? 211 PHE B CE2 1 
ATOM   3345 C CZ  . PHE B 1 137 ? 138.562 120.712 111.231 1.00 32.93  ? 211 PHE B CZ  1 
ATOM   3346 N N   . LEU B 1 138 ? 140.730 115.450 108.176 1.00 38.95  ? 212 LEU B N   1 
ATOM   3347 C CA  . LEU B 1 138 ? 142.162 115.189 108.233 1.00 31.39  ? 212 LEU B CA  1 
ATOM   3348 C C   . LEU B 1 138 ? 142.730 114.710 106.903 1.00 39.82  ? 212 LEU B C   1 
ATOM   3349 O O   . LEU B 1 138 ? 143.893 114.298 106.853 1.00 42.45  ? 212 LEU B O   1 
ATOM   3350 C CB  . LEU B 1 138 ? 142.465 114.162 109.327 1.00 34.27  ? 212 LEU B CB  1 
ATOM   3351 C CG  . LEU B 1 138 ? 141.814 114.399 110.691 1.00 29.21  ? 212 LEU B CG  1 
ATOM   3352 C CD1 . LEU B 1 138 ? 142.188 113.295 111.665 1.00 31.76  ? 212 LEU B CD1 1 
ATOM   3353 C CD2 . LEU B 1 138 ? 142.209 115.759 111.243 1.00 39.21  ? 212 LEU B CD2 1 
ATOM   3354 N N   . THR B 1 139 ? 141.940 114.752 105.829 1.00 37.99  ? 213 THR B N   1 
ATOM   3355 C CA  . THR B 1 139 ? 142.363 114.317 104.498 1.00 30.69  ? 213 THR B CA  1 
ATOM   3356 C C   . THR B 1 139 ? 142.271 115.507 103.553 1.00 29.21  ? 213 THR B C   1 
ATOM   3357 O O   . THR B 1 139 ? 141.224 115.736 102.926 1.00 41.31  ? 213 THR B O   1 
ATOM   3358 C CB  . THR B 1 139 ? 141.509 113.153 104.003 1.00 34.18  ? 213 THR B CB  1 
ATOM   3359 O OG1 . THR B 1 139 ? 140.153 113.588 103.853 1.00 37.52  ? 213 THR B OG1 1 
ATOM   3360 C CG2 . THR B 1 139 ? 141.559 111.999 104.990 1.00 33.20  ? 213 THR B CG2 1 
ATOM   3361 N N   . PRO B 1 140 ? 143.341 116.296 103.421 1.00 21.85  ? 214 PRO B N   1 
ATOM   3362 C CA  . PRO B 1 140 ? 143.272 117.526 102.625 1.00 21.59  ? 214 PRO B CA  1 
ATOM   3363 C C   . PRO B 1 140 ? 143.678 117.399 101.165 1.00 31.02  ? 214 PRO B C   1 
ATOM   3364 O O   . PRO B 1 140 ? 143.452 118.350 100.405 1.00 35.42  ? 214 PRO B O   1 
ATOM   3365 C CB  . PRO B 1 140 ? 144.252 118.439 103.370 1.00 24.39  ? 214 PRO B CB  1 
ATOM   3366 C CG  . PRO B 1 140 ? 145.312 117.496 103.823 1.00 24.72  ? 214 PRO B CG  1 
ATOM   3367 C CD  . PRO B 1 140 ? 144.600 116.209 104.181 1.00 25.52  ? 214 PRO B CD  1 
ATOM   3368 N N   . PHE B 1 141 ? 144.258 116.277 100.746 1.00 30.81  ? 215 PHE B N   1 
ATOM   3369 C CA  . PHE B 1 141 ? 144.808 116.149 99.401  1.00 28.59  ? 215 PHE B CA  1 
ATOM   3370 C C   . PHE B 1 141 ? 143.750 115.603 98.449  1.00 33.26  ? 215 PHE B C   1 
ATOM   3371 O O   . PHE B 1 141 ? 143.181 114.533 98.691  1.00 36.25  ? 215 PHE B O   1 
ATOM   3372 C CB  . PHE B 1 141 ? 146.036 115.242 99.405  1.00 22.50  ? 215 PHE B CB  1 
ATOM   3373 C CG  . PHE B 1 141 ? 147.308 115.944 99.777  1.00 22.66  ? 215 PHE B CG  1 
ATOM   3374 C CD1 . PHE B 1 141 ? 147.975 116.732 98.856  1.00 34.20  ? 215 PHE B CD1 1 
ATOM   3375 C CD2 . PHE B 1 141 ? 147.841 115.810 101.046 1.00 27.81  ? 215 PHE B CD2 1 
ATOM   3376 C CE1 . PHE B 1 141 ? 149.147 117.376 99.196  1.00 32.55  ? 215 PHE B CE1 1 
ATOM   3377 C CE2 . PHE B 1 141 ? 149.013 116.452 101.391 1.00 32.99  ? 215 PHE B CE2 1 
ATOM   3378 C CZ  . PHE B 1 141 ? 149.666 117.236 100.464 1.00 29.63  ? 215 PHE B CZ  1 
ATOM   3379 N N   . SER B 1 142 ? 143.496 116.336 97.368  1.00 35.09  ? 216 SER B N   1 
ATOM   3380 C CA  . SER B 1 142 ? 142.617 115.858 96.311  1.00 33.59  ? 216 SER B CA  1 
ATOM   3381 C C   . SER B 1 142 ? 143.377 114.911 95.393  1.00 39.59  ? 216 SER B C   1 
ATOM   3382 O O   . SER B 1 142 ? 144.563 115.110 95.118  1.00 42.78  ? 216 SER B O   1 
ATOM   3383 C CB  . SER B 1 142 ? 142.056 117.032 95.509  1.00 40.01  ? 216 SER B CB  1 
ATOM   3384 O OG  . SER B 1 142 ? 143.099 117.794 94.927  1.00 39.65  ? 216 SER B OG  1 
ATOM   3385 N N   . PHE B 1 143 ? 142.686 113.872 94.918  1.00 33.98  ? 217 PHE B N   1 
ATOM   3386 C CA  . PHE B 1 143 ? 143.354 112.858 94.112  1.00 30.30  ? 217 PHE B CA  1 
ATOM   3387 C C   . PHE B 1 143 ? 143.703 113.349 92.714  1.00 32.20  ? 217 PHE B C   1 
ATOM   3388 O O   . PHE B 1 143 ? 144.551 112.738 92.055  1.00 43.69  ? 217 PHE B O   1 
ATOM   3389 C CB  . PHE B 1 143 ? 142.493 111.602 94.009  1.00 33.96  ? 217 PHE B CB  1 
ATOM   3390 C CG  . PHE B 1 143 ? 143.263 110.380 93.600  1.00 32.58  ? 217 PHE B CG  1 
ATOM   3391 C CD1 . PHE B 1 143 ? 144.168 109.796 94.468  1.00 34.09  ? 217 PHE B CD1 1 
ATOM   3392 C CD2 . PHE B 1 143 ? 143.093 109.825 92.345  1.00 34.87  ? 217 PHE B CD2 1 
ATOM   3393 C CE1 . PHE B 1 143 ? 144.883 108.677 94.095  1.00 33.59  ? 217 PHE B CE1 1 
ATOM   3394 C CE2 . PHE B 1 143 ? 143.807 108.705 91.966  1.00 38.70  ? 217 PHE B CE2 1 
ATOM   3395 C CZ  . PHE B 1 143 ? 144.703 108.131 92.843  1.00 36.83  ? 217 PHE B CZ  1 
ATOM   3396 N N   . GLU B 1 144 ? 143.073 114.420 92.243  1.00 37.27  ? 218 GLU B N   1 
ATOM   3397 C CA  . GLU B 1 144 ? 143.403 114.948 90.927  1.00 35.54  ? 218 GLU B CA  1 
ATOM   3398 C C   . GLU B 1 144 ? 144.830 115.482 90.913  1.00 33.36  ? 218 GLU B C   1 
ATOM   3399 O O   . GLU B 1 144 ? 145.285 116.114 91.871  1.00 44.36  ? 218 GLU B O   1 
ATOM   3400 C CB  . GLU B 1 144 ? 142.409 116.040 90.523  1.00 44.04  ? 218 GLU B CB  1 
ATOM   3401 C CG  . GLU B 1 144 ? 142.546 117.351 91.283  1.00 45.91  ? 218 GLU B CG  1 
ATOM   3402 C CD  . GLU B 1 144 ? 141.814 118.494 90.608  1.00 48.83  ? 218 GLU B CD  1 
ATOM   3403 O OE1 . GLU B 1 144 ? 140.581 118.394 90.437  1.00 46.82  ? 218 GLU B OE1 1 
ATOM   3404 O OE2 . GLU B 1 144 ? 142.473 119.493 90.248  1.00 50.82  ? 218 GLU B OE2 1 
ATOM   3405 N N   . ASN B 1 145 ? 145.543 115.199 89.822  1.00 30.92  ? 219 ASN B N   1 
ATOM   3406 C CA  . ASN B 1 145 ? 146.937 115.614 89.659  1.00 33.11  ? 219 ASN B CA  1 
ATOM   3407 C C   . ASN B 1 145 ? 147.801 115.129 90.820  1.00 44.60  ? 219 ASN B C   1 
ATOM   3408 O O   . ASN B 1 145 ? 148.642 115.861 91.347  1.00 48.88  ? 219 ASN B O   1 
ATOM   3409 C CB  . ASN B 1 145 ? 147.043 117.132 89.497  1.00 32.92  ? 219 ASN B CB  1 
ATOM   3410 C CG  . ASN B 1 145 ? 148.077 117.537 88.468  1.00 40.76  ? 219 ASN B CG  1 
ATOM   3411 O OD1 . ASN B 1 145 ? 149.093 116.864 88.293  1.00 44.57  ? 219 ASN B OD1 1 
ATOM   3412 N ND2 . ASN B 1 145 ? 147.824 118.643 87.779  1.00 40.56  ? 219 ASN B ND2 1 
ATOM   3413 N N   . PHE B 1 146 ? 147.590 113.875 91.228  1.00 40.45  ? 220 PHE B N   1 
ATOM   3414 C CA  . PHE B 1 146 ? 148.323 113.342 92.370  1.00 23.92  ? 220 PHE B CA  1 
ATOM   3415 C C   . PHE B 1 146 ? 149.785 113.075 92.049  1.00 31.09  ? 220 PHE B C   1 
ATOM   3416 O O   . PHE B 1 146 ? 150.600 112.994 92.973  1.00 47.18  ? 220 PHE B O   1 
ATOM   3417 C CB  . PHE B 1 146 ? 147.657 112.063 92.885  1.00 28.97  ? 220 PHE B CB  1 
ATOM   3418 C CG  . PHE B 1 146 ? 147.869 110.862 92.006  1.00 33.70  ? 220 PHE B CG  1 
ATOM   3419 C CD1 . PHE B 1 146 ? 147.069 110.646 90.898  1.00 39.07  ? 220 PHE B CD1 1 
ATOM   3420 C CD2 . PHE B 1 146 ? 148.856 109.937 92.304  1.00 35.17  ? 220 PHE B CD2 1 
ATOM   3421 C CE1 . PHE B 1 146 ? 147.260 109.538 90.096  1.00 37.63  ? 220 PHE B CE1 1 
ATOM   3422 C CE2 . PHE B 1 146 ? 149.050 108.830 91.506  1.00 35.13  ? 220 PHE B CE2 1 
ATOM   3423 C CZ  . PHE B 1 146 ? 148.251 108.629 90.403  1.00 36.26  ? 220 PHE B CZ  1 
ATOM   3424 N N   . GLN B 1 147 ? 150.136 112.940 90.768  1.00 27.95  ? 221 GLN B N   1 
ATOM   3425 C CA  . GLN B 1 147 ? 151.528 112.700 90.401  1.00 30.16  ? 221 GLN B CA  1 
ATOM   3426 C C   . GLN B 1 147 ? 152.426 113.824 90.899  1.00 40.10  ? 221 GLN B C   1 
ATOM   3427 O O   . GLN B 1 147 ? 153.440 113.580 91.565  1.00 44.80  ? 221 GLN B O   1 
ATOM   3428 C CB  . GLN B 1 147 ? 151.652 112.555 88.884  1.00 35.59  ? 221 GLN B CB  1 
ATOM   3429 C CG  . GLN B 1 147 ? 151.485 111.141 88.358  1.00 37.36  ? 221 GLN B CG  1 
ATOM   3430 C CD  . GLN B 1 147 ? 150.054 110.823 87.978  1.00 37.25  ? 221 GLN B CD  1 
ATOM   3431 O OE1 . GLN B 1 147 ? 149.227 111.721 87.821  1.00 41.23  ? 221 GLN B OE1 1 
ATOM   3432 N NE2 . GLN B 1 147 ? 149.758 109.540 87.809  1.00 38.21  ? 221 GLN B NE2 1 
ATOM   3433 N N   . SER B 1 148 ? 152.057 115.071 90.593  1.00 36.34  ? 222 SER B N   1 
ATOM   3434 C CA  . SER B 1 148 ? 152.875 116.211 90.990  1.00 35.42  ? 222 SER B CA  1 
ATOM   3435 C C   . SER B 1 148 ? 152.931 116.355 92.505  1.00 43.75  ? 222 SER B C   1 
ATOM   3436 O O   . SER B 1 148 ? 153.981 116.690 93.062  1.00 47.73  ? 222 SER B O   1 
ATOM   3437 C CB  . SER B 1 148 ? 152.339 117.489 90.346  1.00 37.18  ? 222 SER B CB  1 
ATOM   3438 O OG  . SER B 1 148 ? 152.923 118.639 90.933  1.00 44.61  ? 222 SER B OG  1 
ATOM   3439 N N   . GLN B 1 149 ? 151.811 116.109 93.189  1.00 36.83  ? 223 GLN B N   1 
ATOM   3440 C CA  . GLN B 1 149 ? 151.787 116.240 94.643  1.00 29.45  ? 223 GLN B CA  1 
ATOM   3441 C C   . GLN B 1 149 ? 152.685 115.201 95.307  1.00 35.94  ? 223 GLN B C   1 
ATOM   3442 O O   . GLN B 1 149 ? 153.462 115.526 96.216  1.00 46.03  ? 223 GLN B O   1 
ATOM   3443 C CB  . GLN B 1 149 ? 150.349 116.124 95.148  1.00 29.56  ? 223 GLN B CB  1 
ATOM   3444 C CG  . GLN B 1 149 ? 149.419 117.188 94.589  1.00 28.42  ? 223 GLN B CG  1 
ATOM   3445 C CD  . GLN B 1 149 ? 148.018 117.096 95.154  1.00 30.92  ? 223 GLN B CD  1 
ATOM   3446 O OE1 . GLN B 1 149 ? 147.477 118.075 95.665  1.00 32.93  ? 223 GLN B OE1 1 
ATOM   3447 N NE2 . GLN B 1 149 ? 147.421 115.913 95.067  1.00 37.17  ? 223 GLN B NE2 1 
ATOM   3448 N N   . VAL B 1 150 ? 152.603 113.947 94.858  1.00 28.70  ? 224 VAL B N   1 
ATOM   3449 C CA  . VAL B 1 150 ? 153.463 112.907 95.415  1.00 23.25  ? 224 VAL B CA  1 
ATOM   3450 C C   . VAL B 1 150 ? 154.924 113.195 95.097  1.00 34.19  ? 224 VAL B C   1 
ATOM   3451 O O   . VAL B 1 150 ? 155.806 112.978 95.936  1.00 45.53  ? 224 VAL B O   1 
ATOM   3452 C CB  . VAL B 1 150 ? 153.031 111.518 94.911  1.00 23.39  ? 224 VAL B CB  1 
ATOM   3453 C CG1 . VAL B 1 150 ? 153.955 110.446 95.456  1.00 29.72  ? 224 VAL B CG1 1 
ATOM   3454 C CG2 . VAL B 1 150 ? 151.605 111.226 95.338  1.00 30.27  ? 224 VAL B CG2 1 
ATOM   3455 N N   . THR B 1 151 ? 155.208 113.692 93.890  1.00 32.06  ? 225 THR B N   1 
ATOM   3456 C CA  . THR B 1 151 ? 156.584 114.034 93.547  1.00 37.12  ? 225 THR B CA  1 
ATOM   3457 C C   . THR B 1 151 ? 157.114 115.150 94.441  1.00 41.26  ? 225 THR B C   1 
ATOM   3458 O O   . THR B 1 151 ? 158.252 115.083 94.920  1.00 46.82  ? 225 THR B O   1 
ATOM   3459 C CB  . THR B 1 151 ? 156.673 114.435 92.075  1.00 38.69  ? 225 THR B CB  1 
ATOM   3460 O OG1 . THR B 1 151 ? 156.244 113.340 91.256  1.00 43.95  ? 225 THR B OG1 1 
ATOM   3461 C CG2 . THR B 1 151 ? 158.103 114.803 91.707  1.00 40.77  ? 225 THR B CG2 1 
ATOM   3462 N N   . GLN B 1 152 ? 156.298 116.177 94.687  1.00 40.39  ? 226 GLN B N   1 
ATOM   3463 C CA  . GLN B 1 152 ? 156.719 117.274 95.552  1.00 38.85  ? 226 GLN B CA  1 
ATOM   3464 C C   . GLN B 1 152 ? 156.956 116.792 96.976  1.00 41.16  ? 226 GLN B C   1 
ATOM   3465 O O   . GLN B 1 152 ? 157.896 117.238 97.643  1.00 45.96  ? 226 GLN B O   1 
ATOM   3466 C CB  . GLN B 1 152 ? 155.674 118.389 95.530  1.00 35.64  ? 226 GLN B CB  1 
ATOM   3467 C CG  . GLN B 1 152 ? 155.815 119.358 94.367  1.00 43.13  ? 226 GLN B CG  1 
ATOM   3468 C CD  . GLN B 1 152 ? 157.256 119.741 94.095  1.00 48.34  ? 226 GLN B CD  1 
ATOM   3469 O OE1 . GLN B 1 152 ? 157.850 120.530 94.830  1.00 52.62  ? 226 GLN B OE1 1 
ATOM   3470 N NE2 . GLN B 1 152 ? 157.826 119.186 93.031  1.00 48.75  ? 226 GLN B NE2 1 
ATOM   3471 N N   . VAL B 1 153 ? 156.107 115.884 97.462  1.00 39.85  ? 227 VAL B N   1 
ATOM   3472 C CA  . VAL B 1 153 ? 156.312 115.320 98.794  1.00 35.23  ? 227 VAL B CA  1 
ATOM   3473 C C   . VAL B 1 153 ? 157.610 114.524 98.845  1.00 39.24  ? 227 VAL B C   1 
ATOM   3474 O O   . VAL B 1 153 ? 158.378 114.621 99.810  1.00 49.91  ? 227 VAL B O   1 
ATOM   3475 C CB  . VAL B 1 153 ? 155.099 114.465 99.203  1.00 37.31  ? 227 VAL B CB  1 
ATOM   3476 C CG1 . VAL B 1 153 ? 155.442 113.591 100.396 1.00 38.44  ? 227 VAL B CG1 1 
ATOM   3477 C CG2 . VAL B 1 153 ? 153.915 115.360 99.522  1.00 42.27  ? 227 VAL B CG2 1 
ATOM   3478 N N   . ILE B 1 154 ? 157.879 113.728 97.807  1.00 36.37  ? 228 ILE B N   1 
ATOM   3479 C CA  . ILE B 1 154 ? 159.093 112.915 97.780  1.00 35.83  ? 228 ILE B CA  1 
ATOM   3480 C C   . ILE B 1 154 ? 160.334 113.800 97.753  1.00 36.65  ? 228 ILE B C   1 
ATOM   3481 O O   . ILE B 1 154 ? 161.336 113.506 98.417  1.00 38.70  ? 228 ILE B O   1 
ATOM   3482 C CB  . ILE B 1 154 ? 159.060 111.943 96.584  1.00 36.98  ? 228 ILE B CB  1 
ATOM   3483 C CG1 . ILE B 1 154 ? 158.017 110.849 96.814  1.00 38.73  ? 228 ILE B CG1 1 
ATOM   3484 C CG2 . ILE B 1 154 ? 160.428 111.323 96.351  1.00 42.41  ? 228 ILE B CG2 1 
ATOM   3485 C CD1 . ILE B 1 154 ? 157.726 110.017 95.586  1.00 40.26  ? 228 ILE B CD1 1 
ATOM   3486 N N   . GLU B 1 155 ? 160.288 114.897 96.991  1.00 37.51  ? 229 GLU B N   1 
ATOM   3487 C CA  . GLU B 1 155 ? 161.445 115.786 96.909  1.00 38.92  ? 229 GLU B CA  1 
ATOM   3488 C C   . GLU B 1 155 ? 161.799 116.367 98.272  1.00 44.83  ? 229 GLU B C   1 
ATOM   3489 O O   . GLU B 1 155 ? 162.978 116.437 98.637  1.00 45.14  ? 229 GLU B O   1 
ATOM   3490 C CB  . GLU B 1 155 ? 161.182 116.906 95.902  1.00 39.74  ? 229 GLU B CB  1 
ATOM   3491 C CG  . GLU B 1 155 ? 161.035 116.439 94.464  1.00 42.41  ? 229 GLU B CG  1 
ATOM   3492 C CD  . GLU B 1 155 ? 162.086 115.421 94.068  1.00 48.83  ? 229 GLU B CD  1 
ATOM   3493 O OE1 . GLU B 1 155 ? 163.221 115.831 93.749  1.00 49.04  ? 229 GLU B OE1 1 
ATOM   3494 O OE2 . GLU B 1 155 ? 161.776 114.210 94.070  1.00 49.27  ? 229 GLU B OE2 1 
ATOM   3495 N N   . GLY B 1 156 ? 160.797 116.788 99.038  1.00 50.47  ? 230 GLY B N   1 
ATOM   3496 C CA  . GLY B 1 156 ? 161.040 117.310 100.368 1.00 44.32  ? 230 GLY B CA  1 
ATOM   3497 C C   . GLY B 1 156 ? 160.563 118.733 100.561 1.00 39.68  ? 230 GLY B C   1 
ATOM   3498 O O   . GLY B 1 156 ? 160.895 119.375 101.562 1.00 44.84  ? 230 GLY B O   1 
ATOM   3499 N N   . ASN B 1 157 ? 159.783 119.242 99.607  1.00 45.23  ? 231 ASN B N   1 
ATOM   3500 C CA  . ASN B 1 157 ? 159.230 120.592 99.689  1.00 52.29  ? 231 ASN B CA  1 
ATOM   3501 C C   . ASN B 1 157 ? 157.772 120.484 100.126 1.00 58.41  ? 231 ASN B C   1 
ATOM   3502 O O   . ASN B 1 157 ? 156.844 120.505 99.318  1.00 61.35  ? 231 ASN B O   1 
ATOM   3503 C CB  . ASN B 1 157 ? 159.374 121.314 98.353  1.00 53.64  ? 231 ASN B CB  1 
ATOM   3504 C CG  . ASN B 1 157 ? 160.815 121.639 98.018  1.00 59.17  ? 231 ASN B CG  1 
ATOM   3505 O OD1 . ASN B 1 157 ? 161.584 122.065 98.880  1.00 59.48  ? 231 ASN B OD1 1 
ATOM   3506 N ND2 . ASN B 1 157 ? 161.190 121.438 96.760  1.00 57.36  ? 231 ASN B ND2 1 
ATOM   3507 N N   . ALA B 1 158 ? 157.577 120.371 101.438 1.00 51.75  ? 232 ALA B N   1 
ATOM   3508 C CA  . ALA B 1 158 ? 156.242 120.235 102.002 1.00 46.00  ? 232 ALA B CA  1 
ATOM   3509 C C   . ALA B 1 158 ? 156.289 120.568 103.485 1.00 50.41  ? 232 ALA B C   1 
ATOM   3510 O O   . ALA B 1 158 ? 157.319 120.392 104.141 1.00 54.91  ? 232 ALA B O   1 
ATOM   3511 C CB  . ALA B 1 158 ? 155.684 118.825 101.788 1.00 47.89  ? 232 ALA B CB  1 
ATOM   3512 N N   . ALA B 1 159 ? 155.163 121.049 104.001 1.00 41.16  ? 233 ALA B N   1 
ATOM   3513 C CA  . ALA B 1 159 ? 155.012 121.375 105.410 1.00 38.50  ? 233 ALA B CA  1 
ATOM   3514 C C   . ALA B 1 159 ? 154.103 120.358 106.087 1.00 38.27  ? 233 ALA B C   1 
ATOM   3515 O O   . ALA B 1 159 ? 153.228 119.763 105.451 1.00 41.62  ? 233 ALA B O   1 
ATOM   3516 C CB  . ALA B 1 159 ? 154.448 122.786 105.594 1.00 36.00  ? 233 ALA B CB  1 
ATOM   3517 N N   . VAL B 1 160 ? 154.320 120.160 107.387 1.00 30.58  ? 234 VAL B N   1 
ATOM   3518 C CA  . VAL B 1 160 ? 153.577 119.180 108.165 1.00 35.06  ? 234 VAL B CA  1 
ATOM   3519 C C   . VAL B 1 160 ? 153.086 119.825 109.453 1.00 34.51  ? 234 VAL B C   1 
ATOM   3520 O O   . VAL B 1 160 ? 153.579 120.870 109.883 1.00 42.30  ? 234 VAL B O   1 
ATOM   3521 C CB  . VAL B 1 160 ? 154.419 117.926 108.489 1.00 31.72  ? 234 VAL B CB  1 
ATOM   3522 C CG1 . VAL B 1 160 ? 154.832 117.211 107.212 1.00 37.26  ? 234 VAL B CG1 1 
ATOM   3523 C CG2 . VAL B 1 160 ? 155.636 118.303 109.315 1.00 32.76  ? 234 VAL B CG2 1 
ATOM   3524 N N   . VAL B 1 161 ? 152.097 119.182 110.068 1.00 24.80  ? 235 VAL B N   1 
ATOM   3525 C CA  . VAL B 1 161 ? 151.611 119.550 111.391 1.00 19.99  ? 235 VAL B CA  1 
ATOM   3526 C C   . VAL B 1 161 ? 151.862 118.379 112.331 1.00 26.85  ? 235 VAL B C   1 
ATOM   3527 O O   . VAL B 1 161 ? 151.601 117.222 111.984 1.00 34.11  ? 235 VAL B O   1 
ATOM   3528 C CB  . VAL B 1 161 ? 150.119 119.948 111.380 1.00 22.67  ? 235 VAL B CB  1 
ATOM   3529 C CG1 . VAL B 1 161 ? 149.906 121.140 110.479 1.00 30.63  ? 235 VAL B CG1 1 
ATOM   3530 C CG2 . VAL B 1 161 ? 149.243 118.797 110.925 1.00 30.99  ? 235 VAL B CG2 1 
ATOM   3531 N N   . LEU B 1 162 ? 152.408 118.679 113.507 1.00 25.92  ? 236 LEU B N   1 
ATOM   3532 C CA  . LEU B 1 162 ? 152.730 117.649 114.493 1.00 20.75  ? 236 LEU B CA  1 
ATOM   3533 C C   . LEU B 1 162 ? 151.509 117.452 115.381 1.00 26.84  ? 236 LEU B C   1 
ATOM   3534 O O   . LEU B 1 162 ? 151.345 118.111 116.408 1.00 36.35  ? 236 LEU B O   1 
ATOM   3535 C CB  . LEU B 1 162 ? 153.964 118.039 115.295 1.00 28.91  ? 236 LEU B CB  1 
ATOM   3536 C CG  . LEU B 1 162 ? 155.248 118.180 114.476 1.00 28.97  ? 236 LEU B CG  1 
ATOM   3537 C CD1 . LEU B 1 162 ? 156.329 118.890 115.278 1.00 36.62  ? 236 LEU B CD1 1 
ATOM   3538 C CD2 . LEU B 1 162 ? 155.729 116.825 113.990 1.00 31.13  ? 236 LEU B CD2 1 
ATOM   3539 N N   . ARG B 1 163 ? 150.642 116.528 114.977 1.00 23.84  ? 237 ARG B N   1 
ATOM   3540 C CA  . ARG B 1 163 ? 149.414 116.258 115.710 1.00 23.68  ? 237 ARG B CA  1 
ATOM   3541 C C   . ARG B 1 163 ? 149.735 115.453 116.962 1.00 27.99  ? 237 ARG B C   1 
ATOM   3542 O O   . ARG B 1 163 ? 150.310 114.363 116.877 1.00 34.87  ? 237 ARG B O   1 
ATOM   3543 C CB  . ARG B 1 163 ? 148.422 115.506 114.827 1.00 22.27  ? 237 ARG B CB  1 
ATOM   3544 C CG  . ARG B 1 163 ? 148.011 116.260 113.579 1.00 19.60  ? 237 ARG B CG  1 
ATOM   3545 C CD  . ARG B 1 163 ? 146.845 115.581 112.888 1.00 24.93  ? 237 ARG B CD  1 
ATOM   3546 N NE  . ARG B 1 163 ? 146.364 116.353 111.751 1.00 21.84  ? 237 ARG B NE  1 
ATOM   3547 C CZ  . ARG B 1 163 ? 145.444 117.304 111.828 1.00 18.19  ? 237 ARG B CZ  1 
ATOM   3548 N NH1 . ARG B 1 163 ? 144.880 117.629 112.979 1.00 23.53  ? 237 ARG B NH1 1 
ATOM   3549 N NH2 . ARG B 1 163 ? 145.081 117.946 110.722 1.00 21.66  ? 237 ARG B NH2 1 
ATOM   3550 N N   . SER B 1 164 ? 149.359 115.986 118.120 1.00 24.41  ? 238 SER B N   1 
ATOM   3551 C CA  . SER B 1 164 ? 149.637 115.310 119.377 1.00 20.15  ? 238 SER B CA  1 
ATOM   3552 C C   . SER B 1 164 ? 148.748 114.083 119.540 1.00 27.02  ? 238 SER B C   1 
ATOM   3553 O O   . SER B 1 164 ? 147.637 114.013 119.008 1.00 32.19  ? 238 SER B O   1 
ATOM   3554 C CB  . SER B 1 164 ? 149.433 116.264 120.553 1.00 27.44  ? 238 SER B CB  1 
ATOM   3555 O OG  . SER B 1 164 ? 150.356 117.338 120.502 1.00 37.22  ? 238 SER B OG  1 
ATOM   3556 N N   . ARG B 1 165 ? 149.254 113.108 120.289 1.00 26.11  ? 239 ARG B N   1 
ATOM   3557 C CA  . ARG B 1 165 ? 148.531 111.884 120.589 1.00 21.57  ? 239 ARG B CA  1 
ATOM   3558 C C   . ARG B 1 165 ? 148.531 111.667 122.095 1.00 28.57  ? 239 ARG B C   1 
ATOM   3559 O O   . ARG B 1 165 ? 149.379 112.196 122.817 1.00 38.46  ? 239 ARG B O   1 
ATOM   3560 C CB  . ARG B 1 165 ? 149.151 110.672 119.881 1.00 27.22  ? 239 ARG B CB  1 
ATOM   3561 C CG  . ARG B 1 165 ? 149.162 110.772 118.367 1.00 25.35  ? 239 ARG B CG  1 
ATOM   3562 C CD  . ARG B 1 165 ? 149.403 109.414 117.733 1.00 23.03  ? 239 ARG B CD  1 
ATOM   3563 N NE  . ARG B 1 165 ? 150.685 108.847 118.132 1.00 27.92  ? 239 ARG B NE  1 
ATOM   3564 C CZ  . ARG B 1 165 ? 151.160 107.688 117.699 1.00 23.03  ? 239 ARG B CZ  1 
ATOM   3565 N NH1 . ARG B 1 165 ? 150.481 106.939 116.846 1.00 24.02  ? 239 ARG B NH1 1 
ATOM   3566 N NH2 . ARG B 1 165 ? 152.345 107.270 118.131 1.00 31.30  ? 239 ARG B NH2 1 
ATOM   3567 N N   . LEU B 1 166 ? 147.568 110.882 122.567 1.00 29.35  ? 240 LEU B N   1 
ATOM   3568 C CA  . LEU B 1 166 ? 147.450 110.579 123.986 1.00 16.49  ? 240 LEU B CA  1 
ATOM   3569 C C   . LEU B 1 166 ? 147.944 109.165 124.258 1.00 25.46  ? 240 LEU B C   1 
ATOM   3570 O O   . LEU B 1 166 ? 147.514 108.211 123.599 1.00 34.61  ? 240 LEU B O   1 
ATOM   3571 C CB  . LEU B 1 166 ? 146.009 110.732 124.472 1.00 23.51  ? 240 LEU B CB  1 
ATOM   3572 C CG  . LEU B 1 166 ? 145.408 112.136 124.490 1.00 29.17  ? 240 LEU B CG  1 
ATOM   3573 C CD1 . LEU B 1 166 ? 143.899 112.065 124.655 1.00 28.47  ? 240 LEU B CD1 1 
ATOM   3574 C CD2 . LEU B 1 166 ? 146.033 112.977 125.590 1.00 27.37  ? 240 LEU B CD2 1 
ATOM   3575 N N   . LYS B 1 167 ? 148.851 109.047 125.223 1.00 27.46  ? 241 LYS B N   1 
ATOM   3576 C CA  . LYS B 1 167 ? 149.320 107.762 125.722 1.00 14.74  ? 241 LYS B CA  1 
ATOM   3577 C C   . LYS B 1 167 ? 148.410 107.330 126.864 1.00 28.85  ? 241 LYS B C   1 
ATOM   3578 O O   . LYS B 1 167 ? 148.273 108.048 127.862 1.00 36.82  ? 241 LYS B O   1 
ATOM   3579 C CB  . LYS B 1 167 ? 150.769 107.866 126.194 1.00 24.46  ? 241 LYS B CB  1 
ATOM   3580 C CG  . LYS B 1 167 ? 151.436 106.535 126.489 1.00 28.62  ? 241 LYS B CG  1 
ATOM   3581 C CD  . LYS B 1 167 ? 152.532 106.699 127.529 1.00 27.56  ? 241 LYS B CD  1 
ATOM   3582 C CE  . LYS B 1 167 ? 152.690 105.446 128.370 1.00 34.46  ? 241 LYS B CE  1 
ATOM   3583 N NZ  . LYS B 1 167 ? 152.681 104.219 127.530 1.00 36.39  ? 241 LYS B NZ  1 
ATOM   3584 N N   . VAL B 1 168 ? 147.788 106.164 126.715 1.00 28.27  ? 242 VAL B N   1 
ATOM   3585 C CA  . VAL B 1 168 ? 146.784 105.673 127.648 1.00 19.91  ? 242 VAL B CA  1 
ATOM   3586 C C   . VAL B 1 168 ? 147.226 104.314 128.170 1.00 29.80  ? 242 VAL B C   1 
ATOM   3587 O O   . VAL B 1 168 ? 147.564 103.421 127.386 1.00 41.73  ? 242 VAL B O   1 
ATOM   3588 C CB  . VAL B 1 168 ? 145.399 105.581 126.985 1.00 28.96  ? 242 VAL B CB  1 
ATOM   3589 C CG1 . VAL B 1 168 ? 144.389 105.001 127.950 1.00 31.69  ? 242 VAL B CG1 1 
ATOM   3590 C CG2 . VAL B 1 168 ? 144.960 106.951 126.507 1.00 32.40  ? 242 VAL B CG2 1 
ATOM   3591 N N   . ARG B 1 169 ? 147.218 104.162 129.489 1.00 38.29  ? 243 ARG B N   1 
ATOM   3592 C CA  . ARG B 1 169 ? 147.600 102.925 130.155 1.00 38.71  ? 243 ARG B CA  1 
ATOM   3593 C C   . ARG B 1 169 ? 146.429 102.456 131.005 1.00 40.83  ? 243 ARG B C   1 
ATOM   3594 O O   . ARG B 1 169 ? 145.950 103.198 131.869 1.00 44.71  ? 243 ARG B O   1 
ATOM   3595 C CB  . ARG B 1 169 ? 148.850 103.134 131.012 1.00 44.08  ? 243 ARG B CB  1 
ATOM   3596 C CG  . ARG B 1 169 ? 149.383 101.879 131.678 1.00 47.33  ? 243 ARG B CG  1 
ATOM   3597 C CD  . ARG B 1 169 ? 150.668 102.178 132.432 1.00 46.84  ? 243 ARG B CD  1 
ATOM   3598 N NE  . ARG B 1 169 ? 151.194 101.002 133.116 1.00 52.39  ? 243 ARG B NE  1 
ATOM   3599 C CZ  . ARG B 1 169 ? 152.311 100.990 133.830 1.00 51.90  ? 243 ARG B CZ  1 
ATOM   3600 N NH1 . ARG B 1 169 ? 153.049 102.078 133.977 1.00 49.51  ? 243 ARG B NH1 1 
ATOM   3601 N NH2 . ARG B 1 169 ? 152.696 99.858  134.413 1.00 49.66  ? 243 ARG B NH2 1 
ATOM   3602 N N   . VAL B 1 170 ? 145.968 101.235 130.759 1.00 41.39  ? 244 VAL B N   1 
ATOM   3603 C CA  . VAL B 1 170 ? 144.850 100.653 131.492 1.00 41.35  ? 244 VAL B CA  1 
ATOM   3604 C C   . VAL B 1 170 ? 145.411 99.650  132.489 1.00 46.60  ? 244 VAL B C   1 
ATOM   3605 O O   . VAL B 1 170 ? 146.092 98.693  132.102 1.00 49.77  ? 244 VAL B O   1 
ATOM   3606 C CB  . VAL B 1 170 ? 143.840 99.989  130.544 1.00 37.03  ? 244 VAL B CB  1 
ATOM   3607 C CG1 . VAL B 1 170 ? 142.564 99.640  131.291 1.00 44.28  ? 244 VAL B CG1 1 
ATOM   3608 C CG2 . VAL B 1 170 ? 143.540 100.901 129.368 1.00 41.76  ? 244 VAL B CG2 1 
ATOM   3609 N N   . VAL B 1 171 ? 145.127 99.864  133.770 1.00 51.71  ? 245 VAL B N   1 
ATOM   3610 C CA  . VAL B 1 171 ? 145.617 99.008  134.843 1.00 52.07  ? 245 VAL B CA  1 
ATOM   3611 C C   . VAL B 1 171 ? 144.434 98.237  135.409 1.00 55.99  ? 245 VAL B C   1 
ATOM   3612 O O   . VAL B 1 171 ? 143.441 98.836  135.845 1.00 58.04  ? 245 VAL B O   1 
ATOM   3613 C CB  . VAL B 1 171 ? 146.326 99.819  135.938 1.00 53.22  ? 245 VAL B CB  1 
ATOM   3614 C CG1 . VAL B 1 171 ? 146.625 98.937  137.140 1.00 55.56  ? 245 VAL B CG1 1 
ATOM   3615 C CG2 . VAL B 1 171 ? 147.604 100.434 135.393 1.00 51.87  ? 245 VAL B CG2 1 
ATOM   3616 N N   . LYS B 1 172 ? 144.543 96.911  135.400 1.00 63.00  ? 246 LYS B N   1 
ATOM   3617 C CA  . LYS B 1 172 ? 143.500 96.021  135.885 1.00 63.92  ? 246 LYS B CA  1 
ATOM   3618 C C   . LYS B 1 172 ? 143.977 95.289  137.132 1.00 69.83  ? 246 LYS B C   1 
ATOM   3619 O O   . LYS B 1 172 ? 145.114 94.810  137.187 1.00 68.96  ? 246 LYS B O   1 
ATOM   3620 C CB  . LYS B 1 172 ? 143.096 95.007  134.810 1.00 59.92  ? 246 LYS B CB  1 
ATOM   3621 C CG  . LYS B 1 172 ? 142.378 95.614  133.615 1.00 60.59  ? 246 LYS B CG  1 
ATOM   3622 C CD  . LYS B 1 172 ? 141.951 94.543  132.624 1.00 64.08  ? 246 LYS B CD  1 
ATOM   3623 C CE  . LYS B 1 172 ? 141.292 95.151  131.397 1.00 64.65  ? 246 LYS B CE  1 
ATOM   3624 N NZ  . LYS B 1 172 ? 139.980 95.775  131.722 1.00 63.46  ? 246 LYS B NZ  1 
ATOM   3625 N N   . GLU B 1 173 ? 143.102 95.205  138.129 1.00 72.76  ? 247 GLU B N   1 
ATOM   3626 C CA  . GLU B 1 173 ? 143.424 94.519  139.375 1.00 68.89  ? 247 GLU B CA  1 
ATOM   3627 C C   . GLU B 1 173 ? 143.037 93.046  139.302 1.00 67.59  ? 247 GLU B C   1 
ATOM   3628 O O   . GLU B 1 173 ? 142.182 92.659  138.506 1.00 68.91  ? 247 GLU B O   1 
ATOM   3629 C CB  . GLU B 1 173 ? 142.720 95.192  140.555 1.00 67.51  ? 247 GLU B CB  1 
ATOM   3630 C CG  . GLU B 1 173 ? 143.057 94.585  141.908 1.00 69.96  ? 247 GLU B CG  1 
ATOM   3631 C CD  . GLU B 1 173 ? 142.379 95.309  143.055 1.00 71.48  ? 247 GLU B CD  1 
ATOM   3632 O OE1 . GLU B 1 173 ? 141.616 96.261  142.791 1.00 70.45  ? 247 GLU B OE1 1 
ATOM   3633 O OE2 . GLU B 1 173 ? 142.611 94.927  144.222 1.00 70.70  ? 247 GLU B OE2 1 
ATOM   3634 N N   . GLN B 1 202 ? 147.547 93.739  134.833 1.00 65.19  ? 276 GLN B N   1 
ATOM   3635 C CA  . GLN B 1 202 ? 147.643 93.596  133.385 1.00 65.45  ? 276 GLN B CA  1 
ATOM   3636 C C   . GLN B 1 202 ? 147.667 94.959  132.702 1.00 65.47  ? 276 GLN B C   1 
ATOM   3637 O O   . GLN B 1 202 ? 146.621 95.515  132.368 1.00 66.56  ? 276 GLN B O   1 
ATOM   3638 C CB  . GLN B 1 202 ? 146.489 92.758  132.858 1.00 65.97  ? 276 GLN B CB  1 
ATOM   3639 N N   . ALA B 1 203 ? 148.868 95.492  132.497 1.00 61.95  ? 277 ALA B N   1 
ATOM   3640 C CA  . ALA B 1 203 ? 149.024 96.788  131.854 1.00 63.72  ? 277 ALA B CA  1 
ATOM   3641 C C   . ALA B 1 203 ? 148.864 96.660  130.345 1.00 62.71  ? 277 ALA B C   1 
ATOM   3642 O O   . ALA B 1 203 ? 149.343 95.702  129.732 1.00 64.52  ? 277 ALA B O   1 
ATOM   3643 C CB  . ALA B 1 203 ? 150.390 97.389  132.186 1.00 61.72  ? 277 ALA B CB  1 
ATOM   3644 N N   . MET B 1 204 ? 148.184 97.637  129.748 1.00 53.38  ? 278 MET B N   1 
ATOM   3645 C CA  . MET B 1 204 ? 147.952 97.664  128.306 1.00 49.66  ? 278 MET B CA  1 
ATOM   3646 C C   . MET B 1 204 ? 148.101 99.101  127.828 1.00 52.82  ? 278 MET B C   1 
ATOM   3647 O O   . MET B 1 204 ? 147.301 99.965  128.200 1.00 56.91  ? 278 MET B O   1 
ATOM   3648 C CB  . MET B 1 204 ? 146.572 97.110  127.955 1.00 50.58  ? 278 MET B CB  1 
ATOM   3649 C CG  . MET B 1 204 ? 146.555 95.615  127.683 1.00 56.89  ? 278 MET B CG  1 
ATOM   3650 S SD  . MET B 1 204 ? 147.859 95.101  126.549 1.00 70.56  ? 278 MET B SD  1 
ATOM   3651 C CE  . MET B 1 204 ? 147.239 95.757  125.002 1.00 54.97  ? 278 MET B CE  1 
ATOM   3652 N N   . GLN B 1 205 ? 149.117 99.354  127.010 1.00 49.39  ? 279 GLN B N   1 
ATOM   3653 C CA  . GLN B 1 205 ? 149.387 100.691 126.506 1.00 43.23  ? 279 GLN B CA  1 
ATOM   3654 C C   . GLN B 1 205 ? 148.687 100.920 125.172 1.00 44.87  ? 279 GLN B C   1 
ATOM   3655 O O   . GLN B 1 205 ? 148.465 99.989  124.393 1.00 47.68  ? 279 GLN B O   1 
ATOM   3656 C CB  . GLN B 1 205 ? 150.891 100.917 126.353 1.00 45.24  ? 279 GLN B CB  1 
ATOM   3657 C CG  . GLN B 1 205 ? 151.648 100.933 127.670 1.00 51.09  ? 279 GLN B CG  1 
ATOM   3658 C CD  . GLN B 1 205 ? 153.139 101.129 127.484 1.00 58.41  ? 279 GLN B CD  1 
ATOM   3659 O OE1 . GLN B 1 205 ? 153.634 101.191 126.358 1.00 56.48  ? 279 GLN B OE1 1 
ATOM   3660 N NE2 . GLN B 1 205 ? 153.865 101.230 128.591 1.00 56.53  ? 279 GLN B NE2 1 
ATOM   3661 N N   . TYR B 1 206 ? 148.344 102.180 124.919 1.00 42.71  ? 280 TYR B N   1 
ATOM   3662 C CA  . TYR B 1 206 ? 147.654 102.584 123.705 1.00 32.95  ? 280 TYR B CA  1 
ATOM   3663 C C   . TYR B 1 206 ? 148.079 104.001 123.355 1.00 40.17  ? 280 TYR B C   1 
ATOM   3664 O O   . TYR B 1 206 ? 148.385 104.806 124.238 1.00 45.14  ? 280 TYR B O   1 
ATOM   3665 C CB  . TYR B 1 206 ? 146.130 102.532 123.869 1.00 34.74  ? 280 TYR B CB  1 
ATOM   3666 C CG  . TYR B 1 206 ? 145.552 101.145 124.023 1.00 39.47  ? 280 TYR B CG  1 
ATOM   3667 C CD1 . TYR B 1 206 ? 145.631 100.217 122.994 1.00 44.59  ? 280 TYR B CD1 1 
ATOM   3668 C CD2 . TYR B 1 206 ? 144.918 100.766 125.198 1.00 41.56  ? 280 TYR B CD2 1 
ATOM   3669 C CE1 . TYR B 1 206 ? 145.099 98.949  123.133 1.00 45.23  ? 280 TYR B CE1 1 
ATOM   3670 C CE2 . TYR B 1 206 ? 144.383 99.502  125.347 1.00 39.42  ? 280 TYR B CE2 1 
ATOM   3671 C CZ  . TYR B 1 206 ? 144.476 98.598  124.313 1.00 42.25  ? 280 TYR B CZ  1 
ATOM   3672 O OH  . TYR B 1 206 ? 143.945 97.338  124.458 1.00 47.76  ? 280 TYR B OH  1 
ATOM   3673 N N   . GLN B 1 207 ? 148.094 104.300 122.061 1.00 34.50  ? 281 GLN B N   1 
ATOM   3674 C CA  . GLN B 1 207 ? 148.289 105.658 121.569 1.00 25.90  ? 281 GLN B CA  1 
ATOM   3675 C C   . GLN B 1 207 ? 147.076 106.034 120.734 1.00 29.39  ? 281 GLN B C   1 
ATOM   3676 O O   . GLN B 1 207 ? 146.798 105.392 119.715 1.00 43.27  ? 281 GLN B O   1 
ATOM   3677 C CB  . GLN B 1 207 ? 149.573 105.779 120.747 1.00 26.61  ? 281 GLN B CB  1 
ATOM   3678 C CG  . GLN B 1 207 ? 150.747 104.994 121.301 1.00 32.31  ? 281 GLN B CG  1 
ATOM   3679 C CD  . GLN B 1 207 ? 151.546 105.782 122.318 1.00 34.98  ? 281 GLN B CD  1 
ATOM   3680 O OE1 . GLN B 1 207 ? 151.583 107.011 122.277 1.00 38.37  ? 281 GLN B OE1 1 
ATOM   3681 N NE2 . GLN B 1 207 ? 152.192 105.077 123.239 1.00 37.02  ? 281 GLN B NE2 1 
ATOM   3682 N N   . VAL B 1 208 ? 146.357 107.066 121.163 1.00 20.88  ? 282 VAL B N   1 
ATOM   3683 C CA  . VAL B 1 208 ? 145.135 107.483 120.488 1.00 16.12  ? 282 VAL B CA  1 
ATOM   3684 C C   . VAL B 1 208 ? 145.354 108.850 119.860 1.00 16.25  ? 282 VAL B C   1 
ATOM   3685 O O   . VAL B 1 208 ? 146.173 109.651 120.324 1.00 27.66  ? 282 VAL B O   1 
ATOM   3686 C CB  . VAL B 1 208 ? 143.923 107.512 121.441 1.00 24.71  ? 282 VAL B CB  1 
ATOM   3687 C CG1 . VAL B 1 208 ? 143.674 106.132 122.022 1.00 32.56  ? 282 VAL B CG1 1 
ATOM   3688 C CG2 . VAL B 1 208 ? 144.138 108.527 122.534 1.00 32.34  ? 282 VAL B CG2 1 
ATOM   3689 N N   . LEU B 1 209 ? 144.605 109.114 118.793 1.00 25.09  ? 283 LEU B N   1 
ATOM   3690 C CA  . LEU B 1 209 ? 144.723 110.350 118.031 1.00 24.75  ? 283 LEU B CA  1 
ATOM   3691 C C   . LEU B 1 209 ? 143.581 111.324 118.268 1.00 32.65  ? 283 LEU B C   1 
ATOM   3692 O O   . LEU B 1 209 ? 143.824 112.525 118.396 1.00 41.13  ? 283 LEU B O   1 
ATOM   3693 C CB  . LEU B 1 209 ? 144.815 110.036 116.533 1.00 33.29  ? 283 LEU B CB  1 
ATOM   3694 C CG  . LEU B 1 209 ? 145.129 111.203 115.593 1.00 32.43  ? 283 LEU B CG  1 
ATOM   3695 C CD1 . LEU B 1 209 ? 146.359 111.961 116.065 1.00 35.07  ? 283 LEU B CD1 1 
ATOM   3696 C CD2 . LEU B 1 209 ? 145.318 110.707 114.170 1.00 30.08  ? 283 LEU B CD2 1 
ATOM   3697 N N   . ASN B 1 210 ? 142.336 110.848 118.331 1.00 32.05  ? 284 ASN B N   1 
ATOM   3698 C CA  . ASN B 1 210 ? 141.204 111.755 118.504 1.00 31.48  ? 284 ASN B CA  1 
ATOM   3699 C C   . ASN B 1 210 ? 140.791 111.904 119.970 1.00 39.57  ? 284 ASN B C   1 
ATOM   3700 O O   . ASN B 1 210 ? 140.865 113.005 120.523 1.00 42.61  ? 284 ASN B O   1 
ATOM   3701 C CB  . ASN B 1 210 ? 140.026 111.290 117.640 1.00 30.39  ? 284 ASN B CB  1 
ATOM   3702 C CG  . ASN B 1 210 ? 140.227 111.583 116.170 1.00 34.84  ? 284 ASN B CG  1 
ATOM   3703 O OD1 . ASN B 1 210 ? 139.903 110.764 115.313 1.00 43.66  ? 284 ASN B OD1 1 
ATOM   3704 N ND2 . ASN B 1 210 ? 140.763 112.759 115.870 1.00 37.66  ? 284 ASN B ND2 1 
ATOM   3705 N N   . GLU B 1 211 ? 140.364 110.817 120.616 1.00 35.70  ? 285 GLU B N   1 
ATOM   3706 C CA  . GLU B 1 211 ? 140.032 110.886 122.037 1.00 27.66  ? 285 GLU B CA  1 
ATOM   3707 C C   . GLU B 1 211 ? 140.037 109.484 122.635 1.00 26.11  ? 285 GLU B C   1 
ATOM   3708 O O   . GLU B 1 211 ? 140.271 108.487 121.948 1.00 39.66  ? 285 GLU B O   1 
ATOM   3709 C CB  . GLU B 1 211 ? 138.662 111.523 122.302 1.00 38.18  ? 285 GLU B CB  1 
ATOM   3710 C CG  . GLU B 1 211 ? 137.454 110.695 121.870 1.00 38.78  ? 285 GLU B CG  1 
ATOM   3711 C CD  . GLU B 1 211 ? 137.069 110.868 120.424 1.00 36.13  ? 285 GLU B CD  1 
ATOM   3712 O OE1 . GLU B 1 211 ? 137.879 111.394 119.647 1.00 42.55  ? 285 GLU B OE1 1 
ATOM   3713 O OE2 . GLU B 1 211 ? 135.943 110.472 120.061 1.00 41.29  ? 285 GLU B OE2 1 
ATOM   3714 N N   . VAL B 1 212 ? 139.769 109.431 123.939 1.00 25.41  ? 286 VAL B N   1 
ATOM   3715 C CA  . VAL B 1 212 ? 139.399 108.216 124.656 1.00 27.11  ? 286 VAL B CA  1 
ATOM   3716 C C   . VAL B 1 212 ? 138.049 108.467 125.312 1.00 26.38  ? 286 VAL B C   1 
ATOM   3717 O O   . VAL B 1 212 ? 137.880 109.466 126.022 1.00 29.89  ? 286 VAL B O   1 
ATOM   3718 C CB  . VAL B 1 212 ? 140.448 107.829 125.712 1.00 19.62  ? 286 VAL B CB  1 
ATOM   3719 C CG1 . VAL B 1 212 ? 140.109 106.488 126.332 1.00 35.08  ? 286 VAL B CG1 1 
ATOM   3720 C CG2 . VAL B 1 212 ? 141.820 107.791 125.095 1.00 28.43  ? 286 VAL B CG2 1 
ATOM   3721 N N   . VAL B 1 213 ? 137.095 107.569 125.082 1.00 24.27  ? 287 VAL B N   1 
ATOM   3722 C CA  . VAL B 1 213 ? 135.726 107.744 125.556 1.00 24.51  ? 287 VAL B CA  1 
ATOM   3723 C C   . VAL B 1 213 ? 135.452 106.719 126.647 1.00 31.77  ? 287 VAL B C   1 
ATOM   3724 O O   . VAL B 1 213 ? 135.550 105.509 126.412 1.00 40.63  ? 287 VAL B O   1 
ATOM   3725 C CB  . VAL B 1 213 ? 134.710 107.614 124.412 1.00 26.90  ? 287 VAL B CB  1 
ATOM   3726 C CG1 . VAL B 1 213 ? 133.301 107.510 124.966 1.00 32.73  ? 287 VAL B CG1 1 
ATOM   3727 C CG2 . VAL B 1 213 ? 134.821 108.797 123.473 1.00 31.37  ? 287 VAL B CG2 1 
ATOM   3728 N N   . ILE B 1 214 ? 135.098 107.200 127.833 1.00 30.06  ? 288 ILE B N   1 
ATOM   3729 C CA  . ILE B 1 214 ? 134.717 106.343 128.948 1.00 30.80  ? 288 ILE B CA  1 
ATOM   3730 C C   . ILE B 1 214 ? 133.222 106.538 129.158 1.00 31.25  ? 288 ILE B C   1 
ATOM   3731 O O   . ILE B 1 214 ? 132.793 107.488 129.818 1.00 35.49  ? 288 ILE B O   1 
ATOM   3732 C CB  . ILE B 1 214 ? 135.512 106.656 130.220 1.00 26.04  ? 288 ILE B CB  1 
ATOM   3733 C CG1 . ILE B 1 214 ? 137.008 106.421 129.990 1.00 34.11  ? 288 ILE B CG1 1 
ATOM   3734 C CG2 . ILE B 1 214 ? 135.025 105.799 131.379 1.00 35.71  ? 288 ILE B CG2 1 
ATOM   3735 C CD1 . ILE B 1 214 ? 137.769 107.667 129.592 1.00 33.51  ? 288 ILE B CD1 1 
ATOM   3736 N N   . ASP B 1 215 ? 132.421 105.631 128.607 1.00 40.64  ? 289 ASP B N   1 
ATOM   3737 C CA  . ASP B 1 215 ? 130.973 105.792 128.624 1.00 38.50  ? 289 ASP B CA  1 
ATOM   3738 C C   . ASP B 1 215 ? 130.260 104.581 129.210 1.00 45.84  ? 289 ASP B C   1 
ATOM   3739 O O   . ASP B 1 215 ? 130.892 103.728 129.842 1.00 52.12  ? 289 ASP B O   1 
ATOM   3740 C CB  . ASP B 1 215 ? 130.464 106.096 127.208 1.00 43.50  ? 289 ASP B CB  1 
ATOM   3741 C CG  . ASP B 1 215 ? 130.592 104.907 126.243 1.00 50.82  ? 289 ASP B CG  1 
ATOM   3742 O OD1 . ASP B 1 215 ? 130.621 103.737 126.669 1.00 51.13  ? 289 ASP B OD1 1 
ATOM   3743 O OD2 . ASP B 1 215 ? 130.672 105.159 125.021 1.00 51.83  ? 289 ASP B OD2 1 
ATOM   3744 N N   . ARG B 1 216 ? 128.945 104.499 129.009 1.00 51.00  ? 290 ARG B N   1 
ATOM   3745 C CA  . ARG B 1 216 ? 128.190 103.310 129.378 1.00 50.15  ? 290 ARG B CA  1 
ATOM   3746 C C   . ARG B 1 216 ? 127.873 102.500 128.124 1.00 51.54  ? 290 ARG B C   1 
ATOM   3747 O O   . ARG B 1 216 ? 127.707 103.056 127.034 1.00 53.03  ? 290 ARG B O   1 
ATOM   3748 C CB  . ARG B 1 216 ? 126.879 103.636 130.102 1.00 52.32  ? 290 ARG B CB  1 
ATOM   3749 C CG  . ARG B 1 216 ? 125.826 104.336 129.263 1.00 56.14  ? 290 ARG B CG  1 
ATOM   3750 C CD  . ARG B 1 216 ? 124.619 104.698 130.112 1.00 57.58  ? 290 ARG B CD  1 
ATOM   3751 N NE  . ARG B 1 216 ? 123.530 105.291 129.345 1.00 57.30  ? 290 ARG B NE  1 
ATOM   3752 C CZ  . ARG B 1 216 ? 123.424 106.582 129.079 1.00 56.34  ? 290 ARG B CZ  1 
ATOM   3753 N NH1 . ARG B 1 216 ? 124.359 107.433 129.452 1.00 58.04  ? 290 ARG B NH1 1 
ATOM   3754 N NH2 . ARG B 1 216 ? 122.353 107.026 128.426 1.00 54.57  ? 290 ARG B NH2 1 
ATOM   3755 N N   . GLY B 1 217 ? 127.814 101.180 128.280 1.00 60.68  ? 291 GLY B N   1 
ATOM   3756 C CA  . GLY B 1 217 ? 127.440 100.307 127.194 1.00 59.61  ? 291 GLY B CA  1 
ATOM   3757 C C   . GLY B 1 217 ? 125.950 100.031 127.174 1.00 58.13  ? 291 GLY B C   1 
ATOM   3758 O O   . GLY B 1 217 ? 125.129 100.919 126.920 1.00 59.28  ? 291 GLY B O   1 
ATOM   3759 N N   . PRO B 1 218 ? 125.571 98.779  127.442 1.00 57.07  ? 292 PRO B N   1 
ATOM   3760 C CA  . PRO B 1 218 ? 124.143 98.426  127.459 1.00 60.90  ? 292 PRO B CA  1 
ATOM   3761 C C   . PRO B 1 218 ? 123.369 99.051  128.608 1.00 61.14  ? 292 PRO B C   1 
ATOM   3762 O O   . PRO B 1 218 ? 122.132 99.021  128.577 1.00 61.31  ? 292 PRO B O   1 
ATOM   3763 C CB  . PRO B 1 218 ? 124.163 96.897  127.575 1.00 63.13  ? 292 PRO B CB  1 
ATOM   3764 C CG  . PRO B 1 218 ? 125.459 96.601  128.224 1.00 63.20  ? 292 PRO B CG  1 
ATOM   3765 C CD  . PRO B 1 218 ? 126.427 97.610  127.692 1.00 58.03  ? 292 PRO B CD  1 
ATOM   3766 N N   . SER B 1 219 ? 124.045 99.606  129.612 1.00 59.40  ? 293 SER B N   1 
ATOM   3767 C CA  . SER B 1 219 ? 123.357 100.196 130.754 1.00 55.73  ? 293 SER B CA  1 
ATOM   3768 C C   . SER B 1 219 ? 122.505 101.384 130.322 1.00 56.93  ? 293 SER B C   1 
ATOM   3769 O O   . SER B 1 219 ? 122.890 102.161 129.445 1.00 58.62  ? 293 SER B O   1 
ATOM   3770 C CB  . SER B 1 219 ? 124.371 100.635 131.810 1.00 56.26  ? 293 SER B CB  1 
ATOM   3771 O OG  . SER B 1 219 ? 123.753 101.406 132.823 1.00 56.36  ? 293 SER B OG  1 
ATOM   3772 N N   . SER B 1 220 ? 121.321 101.504 130.923 1.00 69.38  ? 294 SER B N   1 
ATOM   3773 C CA  . SER B 1 220 ? 120.425 102.621 130.659 1.00 71.13  ? 294 SER B CA  1 
ATOM   3774 C C   . SER B 1 220 ? 120.431 103.662 131.769 1.00 69.54  ? 294 SER B C   1 
ATOM   3775 O O   . SER B 1 220 ? 119.731 104.674 131.653 1.00 68.93  ? 294 SER B O   1 
ATOM   3776 C CB  . SER B 1 220 ? 118.995 102.113 130.444 1.00 69.53  ? 294 SER B CB  1 
ATOM   3777 O OG  . SER B 1 220 ? 118.931 101.265 129.312 1.00 68.45  ? 294 SER B OG  1 
ATOM   3778 N N   . TYR B 1 221 ? 121.197 103.444 132.830 1.00 69.55  ? 295 TYR B N   1 
ATOM   3779 C CA  . TYR B 1 221 ? 121.272 104.394 133.926 1.00 71.17  ? 295 TYR B CA  1 
ATOM   3780 C C   . TYR B 1 221 ? 122.492 105.299 133.764 1.00 70.45  ? 295 TYR B C   1 
ATOM   3781 O O   . TYR B 1 221 ? 123.364 105.072 132.925 1.00 68.69  ? 295 TYR B O   1 
ATOM   3782 C CB  . TYR B 1 221 ? 121.312 103.657 135.266 1.00 71.39  ? 295 TYR B CB  1 
ATOM   3783 C CG  . TYR B 1 221 ? 120.230 102.608 135.416 1.00 75.53  ? 295 TYR B CG  1 
ATOM   3784 C CD1 . TYR B 1 221 ? 118.892 102.970 135.532 1.00 73.94  ? 295 TYR B CD1 1 
ATOM   3785 C CD2 . TYR B 1 221 ? 120.545 101.256 135.433 1.00 72.58  ? 295 TYR B CD2 1 
ATOM   3786 C CE1 . TYR B 1 221 ? 117.898 102.012 135.666 1.00 73.51  ? 295 TYR B CE1 1 
ATOM   3787 C CE2 . TYR B 1 221 ? 119.559 100.293 135.566 1.00 71.40  ? 295 TYR B CE2 1 
ATOM   3788 C CZ  . TYR B 1 221 ? 118.238 100.677 135.682 1.00 74.62  ? 295 TYR B CZ  1 
ATOM   3789 O OH  . TYR B 1 221 ? 117.254 99.723  135.814 1.00 72.87  ? 295 TYR B OH  1 
ATOM   3790 N N   . LEU B 1 222 ? 122.543 106.342 134.586 1.00 59.41  ? 296 LEU B N   1 
ATOM   3791 C CA  . LEU B 1 222 ? 123.661 107.274 134.542 1.00 56.40  ? 296 LEU B CA  1 
ATOM   3792 C C   . LEU B 1 222 ? 124.956 106.578 134.953 1.00 56.60  ? 296 LEU B C   1 
ATOM   3793 O O   . LEU B 1 222 ? 124.959 105.645 135.760 1.00 59.36  ? 296 LEU B O   1 
ATOM   3794 C CB  . LEU B 1 222 ? 123.395 108.472 135.459 1.00 55.38  ? 296 LEU B CB  1 
ATOM   3795 C CG  . LEU B 1 222 ? 122.462 109.593 134.981 1.00 52.15  ? 296 LEU B CG  1 
ATOM   3796 C CD1 . LEU B 1 222 ? 121.014 109.123 134.896 1.00 55.37  ? 296 LEU B CD1 1 
ATOM   3797 C CD2 . LEU B 1 222 ? 122.574 110.818 135.883 1.00 54.22  ? 296 LEU B CD2 1 
ATOM   3798 N N   . SER B 1 223 ? 126.068 107.042 134.388 1.00 52.05  ? 297 SER B N   1 
ATOM   3799 C CA  . SER B 1 223 ? 127.391 106.517 134.702 1.00 50.60  ? 297 SER B CA  1 
ATOM   3800 C C   . SER B 1 223 ? 128.106 107.507 135.605 1.00 52.39  ? 297 SER B C   1 
ATOM   3801 O O   . SER B 1 223 ? 128.089 108.717 135.347 1.00 49.40  ? 297 SER B O   1 
ATOM   3802 C CB  . SER B 1 223 ? 128.229 106.274 133.445 1.00 52.97  ? 297 SER B CB  1 
ATOM   3803 O OG  . SER B 1 223 ? 129.528 105.807 133.768 1.00 55.15  ? 297 SER B OG  1 
ATOM   3804 N N   . ASN B 1 224 ? 128.741 106.989 136.648 1.00 56.46  ? 298 ASN B N   1 
ATOM   3805 C CA  . ASN B 1 224 ? 129.350 107.797 137.695 1.00 48.73  ? 298 ASN B CA  1 
ATOM   3806 C C   . ASN B 1 224 ? 130.842 107.504 137.672 1.00 46.81  ? 298 ASN B C   1 
ATOM   3807 O O   . ASN B 1 224 ? 131.263 106.439 138.136 1.00 50.28  ? 298 ASN B O   1 
ATOM   3808 C CB  . ASN B 1 224 ? 128.765 107.422 139.053 1.00 45.81  ? 298 ASN B CB  1 
ATOM   3809 C CG  . ASN B 1 224 ? 127.291 107.122 138.986 1.00 56.28  ? 298 ASN B CG  1 
ATOM   3810 O OD1 . ASN B 1 224 ? 126.860 105.997 139.224 1.00 58.02  ? 298 ASN B OD1 1 
ATOM   3811 N ND2 . ASN B 1 224 ? 126.517 108.104 138.591 1.00 54.91  ? 298 ASN B ND2 1 
ATOM   3812 N N   . VAL B 1 225 ? 131.655 108.420 137.142 1.00 39.15  ? 299 VAL B N   1 
ATOM   3813 C CA  . VAL B 1 225 ? 133.095 108.154 137.103 1.00 31.89  ? 299 VAL B CA  1 
ATOM   3814 C C   . VAL B 1 225 ? 133.887 109.348 137.620 1.00 34.12  ? 299 VAL B C   1 
ATOM   3815 O O   . VAL B 1 225 ? 133.550 110.505 137.348 1.00 38.59  ? 299 VAL B O   1 
ATOM   3816 C CB  . VAL B 1 225 ? 133.594 107.733 135.699 1.00 32.92  ? 299 VAL B CB  1 
ATOM   3817 C CG1 . VAL B 1 225 ? 132.930 106.442 135.256 1.00 39.67  ? 299 VAL B CG1 1 
ATOM   3818 C CG2 . VAL B 1 225 ? 133.363 108.797 134.687 1.00 36.05  ? 299 VAL B CG2 1 
ATOM   3819 N N   . ASP B 1 226 ? 134.956 109.052 138.361 1.00 40.17  ? 300 ASP B N   1 
ATOM   3820 C CA  . ASP B 1 226 ? 135.808 110.049 138.993 1.00 36.91  ? 300 ASP B CA  1 
ATOM   3821 C C   . ASP B 1 226 ? 137.033 110.298 138.122 1.00 36.42  ? 300 ASP B C   1 
ATOM   3822 O O   . ASP B 1 226 ? 137.609 109.356 137.563 1.00 43.18  ? 300 ASP B O   1 
ATOM   3823 C CB  . ASP B 1 226 ? 136.261 109.577 140.376 1.00 39.00  ? 300 ASP B CB  1 
ATOM   3824 C CG  . ASP B 1 226 ? 135.212 109.793 141.440 1.00 49.12  ? 300 ASP B CG  1 
ATOM   3825 O OD1 . ASP B 1 226 ? 134.027 109.947 141.083 1.00 49.39  ? 300 ASP B OD1 1 
ATOM   3826 O OD2 . ASP B 1 226 ? 135.579 109.816 142.633 1.00 49.42  ? 300 ASP B OD2 1 
ATOM   3827 N N   . VAL B 1 227 ? 137.433 111.566 138.006 1.00 29.80  ? 301 VAL B N   1 
ATOM   3828 C CA  . VAL B 1 227 ? 138.627 111.940 137.257 1.00 29.05  ? 301 VAL B CA  1 
ATOM   3829 C C   . VAL B 1 227 ? 139.585 112.668 138.193 1.00 30.99  ? 301 VAL B C   1 
ATOM   3830 O O   . VAL B 1 227 ? 139.166 113.522 138.983 1.00 36.69  ? 301 VAL B O   1 
ATOM   3831 C CB  . VAL B 1 227 ? 138.285 112.792 136.018 1.00 28.01  ? 301 VAL B CB  1 
ATOM   3832 C CG1 . VAL B 1 227 ? 137.587 114.078 136.412 1.00 32.57  ? 301 VAL B CG1 1 
ATOM   3833 C CG2 . VAL B 1 227 ? 139.545 113.088 135.209 1.00 32.33  ? 301 VAL B CG2 1 
ATOM   3834 N N   . TYR B 1 228 ? 140.862 112.300 138.125 1.00 30.26  ? 302 TYR B N   1 
ATOM   3835 C CA  . TYR B 1 228 ? 141.928 112.878 138.928 1.00 26.07  ? 302 TYR B CA  1 
ATOM   3836 C C   . TYR B 1 228 ? 142.937 113.534 137.998 1.00 33.09  ? 302 TYR B C   1 
ATOM   3837 O O   . TYR B 1 228 ? 143.223 113.010 136.918 1.00 41.16  ? 302 TYR B O   1 
ATOM   3838 C CB  . TYR B 1 228 ? 142.651 111.809 139.763 1.00 23.16  ? 302 TYR B CB  1 
ATOM   3839 C CG  . TYR B 1 228 ? 141.813 111.087 140.796 1.00 21.21  ? 302 TYR B CG  1 
ATOM   3840 C CD1 . TYR B 1 228 ? 140.760 110.264 140.418 1.00 32.91  ? 302 TYR B CD1 1 
ATOM   3841 C CD2 . TYR B 1 228 ? 142.094 111.207 142.148 1.00 29.28  ? 302 TYR B CD2 1 
ATOM   3842 C CE1 . TYR B 1 228 ? 140.002 109.595 141.358 1.00 33.71  ? 302 TYR B CE1 1 
ATOM   3843 C CE2 . TYR B 1 228 ? 141.341 110.544 143.095 1.00 29.63  ? 302 TYR B CE2 1 
ATOM   3844 C CZ  . TYR B 1 228 ? 140.297 109.739 142.696 1.00 33.25  ? 302 TYR B CZ  1 
ATOM   3845 O OH  . TYR B 1 228 ? 139.548 109.078 143.642 1.00 37.97  ? 302 TYR B OH  1 
ATOM   3846 N N   . LEU B 1 229 ? 143.489 114.668 138.418 1.00 31.82  ? 303 LEU B N   1 
ATOM   3847 C CA  . LEU B 1 229 ? 144.563 115.323 137.683 1.00 24.20  ? 303 LEU B CA  1 
ATOM   3848 C C   . LEU B 1 229 ? 145.731 115.515 138.638 1.00 26.43  ? 303 LEU B C   1 
ATOM   3849 O O   . LEU B 1 229 ? 145.592 116.196 139.660 1.00 37.90  ? 303 LEU B O   1 
ATOM   3850 C CB  . LEU B 1 229 ? 144.100 116.659 137.091 1.00 30.08  ? 303 LEU B CB  1 
ATOM   3851 C CG  . LEU B 1 229 ? 145.042 117.463 136.183 1.00 35.24  ? 303 LEU B CG  1 
ATOM   3852 C CD1 . LEU B 1 229 ? 144.226 118.438 135.354 1.00 30.35  ? 303 LEU B CD1 1 
ATOM   3853 C CD2 . LEU B 1 229 ? 146.135 118.208 136.936 1.00 36.38  ? 303 LEU B CD2 1 
ATOM   3854 N N   . ASP B 1 230 ? 146.875 114.917 138.301 1.00 31.28  ? 304 ASP B N   1 
ATOM   3855 C CA  . ASP B 1 230 ? 148.084 114.991 139.122 1.00 30.11  ? 304 ASP B CA  1 
ATOM   3856 C C   . ASP B 1 230 ? 147.825 114.498 140.543 1.00 32.86  ? 304 ASP B C   1 
ATOM   3857 O O   . ASP B 1 230 ? 148.346 115.046 141.516 1.00 40.05  ? 304 ASP B O   1 
ATOM   3858 C CB  . ASP B 1 230 ? 148.659 116.409 139.133 1.00 38.14  ? 304 ASP B CB  1 
ATOM   3859 C CG  . ASP B 1 230 ? 149.528 116.695 137.925 1.00 44.23  ? 304 ASP B CG  1 
ATOM   3860 O OD1 . ASP B 1 230 ? 150.208 115.763 137.448 1.00 42.72  ? 304 ASP B OD1 1 
ATOM   3861 O OD2 . ASP B 1 230 ? 149.531 117.850 137.452 1.00 40.71  ? 304 ASP B OD2 1 
ATOM   3862 N N   . GLY B 1 231 ? 147.016 113.448 140.664 1.00 28.04  ? 305 GLY B N   1 
ATOM   3863 C CA  . GLY B 1 231 ? 146.697 112.871 141.950 1.00 27.22  ? 305 GLY B CA  1 
ATOM   3864 C C   . GLY B 1 231 ? 145.624 113.590 142.734 1.00 22.74  ? 305 GLY B C   1 
ATOM   3865 O O   . GLY B 1 231 ? 145.348 113.197 143.875 1.00 31.96  ? 305 GLY B O   1 
ATOM   3866 N N   . HIS B 1 232 ? 145.008 114.622 142.169 1.00 26.24  ? 306 HIS B N   1 
ATOM   3867 C CA  . HIS B 1 232 ? 143.995 115.412 142.855 1.00 25.50  ? 306 HIS B CA  1 
ATOM   3868 C C   . HIS B 1 232 ? 142.643 115.176 142.199 1.00 30.55  ? 306 HIS B C   1 
ATOM   3869 O O   . HIS B 1 232 ? 142.510 115.308 140.978 1.00 38.48  ? 306 HIS B O   1 
ATOM   3870 C CB  . HIS B 1 232 ? 144.347 116.900 142.816 1.00 31.38  ? 306 HIS B CB  1 
ATOM   3871 C CG  . HIS B 1 232 ? 145.470 117.280 143.730 1.00 35.34  ? 306 HIS B CG  1 
ATOM   3872 N ND1 . HIS B 1 232 ? 145.984 116.419 144.675 1.00 39.05  ? 306 HIS B ND1 1 
ATOM   3873 C CD2 . HIS B 1 232 ? 146.181 118.427 143.840 1.00 36.81  ? 306 HIS B CD2 1 
ATOM   3874 C CE1 . HIS B 1 232 ? 146.962 117.019 145.329 1.00 35.57  ? 306 HIS B CE1 1 
ATOM   3875 N NE2 . HIS B 1 232 ? 147.102 118.239 144.841 1.00 39.81  ? 306 HIS B NE2 1 
ATOM   3876 N N   . LEU B 1 233 ? 141.645 114.837 143.009 1.00 23.87  ? 307 LEU B N   1 
ATOM   3877 C CA  . LEU B 1 233 ? 140.295 114.593 142.509 1.00 23.30  ? 307 LEU B CA  1 
ATOM   3878 C C   . LEU B 1 233 ? 139.686 115.920 142.083 1.00 24.76  ? 307 LEU B C   1 
ATOM   3879 O O   . LEU B 1 233 ? 139.274 116.726 142.920 1.00 37.74  ? 307 LEU B O   1 
ATOM   3880 C CB  . LEU B 1 233 ? 139.445 113.914 143.577 1.00 28.23  ? 307 LEU B CB  1 
ATOM   3881 C CG  . LEU B 1 233 ? 138.022 113.516 143.181 1.00 28.30  ? 307 LEU B CG  1 
ATOM   3882 C CD1 . LEU B 1 233 ? 138.035 112.629 141.948 1.00 31.55  ? 307 LEU B CD1 1 
ATOM   3883 C CD2 . LEU B 1 233 ? 137.316 112.825 144.336 1.00 29.83  ? 307 LEU B CD2 1 
ATOM   3884 N N   . ILE B 1 234 ? 139.627 116.157 140.774 1.00 25.40  ? 308 ILE B N   1 
ATOM   3885 C CA  . ILE B 1 234 ? 139.087 117.420 140.284 1.00 27.25  ? 308 ILE B CA  1 
ATOM   3886 C C   . ILE B 1 234 ? 137.566 117.382 140.258 1.00 32.28  ? 308 ILE B C   1 
ATOM   3887 O O   . ILE B 1 234 ? 136.904 118.327 140.703 1.00 41.00  ? 308 ILE B O   1 
ATOM   3888 C CB  . ILE B 1 234 ? 139.677 117.765 138.904 1.00 26.69  ? 308 ILE B CB  1 
ATOM   3889 C CG1 . ILE B 1 234 ? 139.691 116.540 137.991 1.00 36.50  ? 308 ILE B CG1 1 
ATOM   3890 C CG2 . ILE B 1 234 ? 141.081 118.322 139.055 1.00 37.65  ? 308 ILE B CG2 1 
ATOM   3891 C CD1 . ILE B 1 234 ? 140.077 116.854 136.564 1.00 37.39  ? 308 ILE B CD1 1 
ATOM   3892 N N   . THR B 1 235 ? 136.984 116.295 139.754 1.00 31.01  ? 309 THR B N   1 
ATOM   3893 C CA  . THR B 1 235 ? 135.532 116.180 139.738 1.00 33.56  ? 309 THR B CA  1 
ATOM   3894 C C   . THR B 1 235 ? 135.118 114.735 139.496 1.00 26.11  ? 309 THR B C   1 
ATOM   3895 O O   . THR B 1 235 ? 135.932 113.863 139.171 1.00 41.43  ? 309 THR B O   1 
ATOM   3896 C CB  . THR B 1 235 ? 134.900 117.092 138.680 1.00 41.51  ? 309 THR B CB  1 
ATOM   3897 O OG1 . THR B 1 235 ? 133.477 117.105 138.852 1.00 47.67  ? 309 THR B OG1 1 
ATOM   3898 C CG2 . THR B 1 235 ? 135.225 116.599 137.282 1.00 35.39  ? 309 THR B CG2 1 
ATOM   3899 N N   . THR B 1 236 ? 133.826 114.502 139.697 1.00 27.93  ? 310 THR B N   1 
ATOM   3900 C CA  . THR B 1 236 ? 133.137 113.288 139.293 1.00 35.86  ? 310 THR B CA  1 
ATOM   3901 C C   . THR B 1 236 ? 132.050 113.667 138.301 1.00 35.56  ? 310 THR B C   1 
ATOM   3902 O O   . THR B 1 236 ? 131.371 114.685 138.471 1.00 39.37  ? 310 THR B O   1 
ATOM   3903 C CB  . THR B 1 236 ? 132.530 112.557 140.496 1.00 39.08  ? 310 THR B CB  1 
ATOM   3904 O OG1 . THR B 1 236 ? 131.808 111.403 140.046 1.00 38.81  ? 310 THR B OG1 1 
ATOM   3905 C CG2 . THR B 1 236 ? 131.602 113.468 141.288 1.00 41.30  ? 310 THR B CG2 1 
ATOM   3906 N N   . VAL B 1 237 ? 131.891 112.865 137.255 1.00 41.32  ? 311 VAL B N   1 
ATOM   3907 C CA  . VAL B 1 237 ? 130.912 113.153 136.219 1.00 38.51  ? 311 VAL B CA  1 
ATOM   3908 C C   . VAL B 1 237 ? 129.779 112.143 136.311 1.00 42.32  ? 311 VAL B C   1 
ATOM   3909 O O   . VAL B 1 237 ? 129.997 110.944 136.558 1.00 47.47  ? 311 VAL B O   1 
ATOM   3910 C CB  . VAL B 1 237 ? 131.523 113.185 134.803 1.00 40.56  ? 311 VAL B CB  1 
ATOM   3911 C CG1 . VAL B 1 237 ? 132.563 114.287 134.708 1.00 43.96  ? 311 VAL B CG1 1 
ATOM   3912 C CG2 . VAL B 1 237 ? 132.125 111.875 134.453 1.00 39.99  ? 311 VAL B CG2 1 
ATOM   3913 N N   . GLN B 1 238 ? 128.568 112.665 136.115 1.00 45.11  ? 312 GLN B N   1 
ATOM   3914 C CA  . GLN B 1 238 ? 127.281 112.040 136.396 1.00 45.67  ? 312 GLN B CA  1 
ATOM   3915 C C   . GLN B 1 238 ? 126.519 112.035 135.077 1.00 49.75  ? 312 GLN B C   1 
ATOM   3916 O O   . GLN B 1 238 ? 125.666 112.897 134.851 1.00 53.64  ? 312 GLN B O   1 
ATOM   3917 C CB  . GLN B 1 238 ? 126.516 112.857 137.452 1.00 48.77  ? 312 GLN B CB  1 
ATOM   3918 C CG  . GLN B 1 238 ? 127.175 112.979 138.814 1.00 51.52  ? 312 GLN B CG  1 
ATOM   3919 C CD  . GLN B 1 238 ? 127.177 111.693 139.590 1.00 54.24  ? 312 GLN B CD  1 
ATOM   3920 O OE1 . GLN B 1 238 ? 126.205 110.942 139.566 1.00 53.93  ? 312 GLN B OE1 1 
ATOM   3921 N NE2 . GLN B 1 238 ? 128.276 111.423 140.286 1.00 52.04  ? 312 GLN B NE2 1 
ATOM   3922 N N   . GLY B 1 239 ? 126.815 111.079 134.206 1.00 50.70  ? 313 GLY B N   1 
ATOM   3923 C CA  . GLY B 1 239 ? 126.144 111.068 132.915 1.00 44.74  ? 313 GLY B CA  1 
ATOM   3924 C C   . GLY B 1 239 ? 126.666 109.980 132.009 1.00 48.36  ? 313 GLY B C   1 
ATOM   3925 O O   . GLY B 1 239 ? 127.063 108.906 132.466 1.00 58.23  ? 313 GLY B O   1 
ATOM   3926 N N   . ASP B 1 240 ? 126.648 110.271 130.709 1.00 39.30  ? 314 ASP B N   1 
ATOM   3927 C CA  . ASP B 1 240 ? 127.061 109.278 129.725 1.00 35.40  ? 314 ASP B CA  1 
ATOM   3928 C C   . ASP B 1 240 ? 128.554 108.984 129.824 1.00 37.83  ? 314 ASP B C   1 
ATOM   3929 O O   . ASP B 1 240 ? 128.962 107.819 129.863 1.00 47.74  ? 314 ASP B O   1 
ATOM   3930 C CB  . ASP B 1 240 ? 126.691 109.751 128.319 1.00 40.72  ? 314 ASP B CB  1 
ATOM   3931 C CG  . ASP B 1 240 ? 125.192 109.803 128.089 1.00 44.11  ? 314 ASP B CG  1 
ATOM   3932 O OD1 . ASP B 1 240 ? 124.444 109.820 129.092 1.00 45.04  ? 314 ASP B OD1 1 
ATOM   3933 O OD2 . ASP B 1 240 ? 124.766 109.823 126.906 1.00 45.29  ? 314 ASP B OD2 1 
ATOM   3934 N N   . GLY B 1 241 ? 129.385 110.021 129.870 1.00 31.18  ? 315 GLY B N   1 
ATOM   3935 C CA  . GLY B 1 241 ? 130.815 109.805 129.987 1.00 31.74  ? 315 GLY B CA  1 
ATOM   3936 C C   . GLY B 1 241 ? 131.608 111.054 129.658 1.00 31.76  ? 315 GLY B C   1 
ATOM   3937 O O   . GLY B 1 241 ? 131.076 112.166 129.649 1.00 39.93  ? 315 GLY B O   1 
ATOM   3938 N N   . VAL B 1 242 ? 132.897 110.842 129.396 1.00 28.08  ? 316 VAL B N   1 
ATOM   3939 C CA  . VAL B 1 242 ? 133.851 111.908 129.125 1.00 28.45  ? 316 VAL B CA  1 
ATOM   3940 C C   . VAL B 1 242 ? 134.554 111.638 127.801 1.00 35.70  ? 316 VAL B C   1 
ATOM   3941 O O   . VAL B 1 242 ? 134.660 110.492 127.353 1.00 42.17  ? 316 VAL B O   1 
ATOM   3942 C CB  . VAL B 1 242 ? 134.883 112.055 130.261 1.00 29.54  ? 316 VAL B CB  1 
ATOM   3943 C CG1 . VAL B 1 242 ? 134.207 112.496 131.539 1.00 30.30  ? 316 VAL B CG1 1 
ATOM   3944 C CG2 . VAL B 1 242 ? 135.605 110.740 130.478 1.00 33.43  ? 316 VAL B CG2 1 
ATOM   3945 N N   . ILE B 1 243 ? 135.033 112.714 127.174 1.00 30.45  ? 317 ILE B N   1 
ATOM   3946 C CA  . ILE B 1 243 ? 135.620 112.662 125.836 1.00 23.95  ? 317 ILE B CA  1 
ATOM   3947 C C   . ILE B 1 243 ? 137.038 113.223 125.868 1.00 34.56  ? 317 ILE B C   1 
ATOM   3948 O O   . ILE B 1 243 ? 137.416 114.006 124.989 1.00 49.04  ? 317 ILE B O   1 
ATOM   3949 C CB  . ILE B 1 243 ? 134.761 113.413 124.801 1.00 26.63  ? 317 ILE B CB  1 
ATOM   3950 C CG1 . ILE B 1 243 ? 133.305 113.004 124.913 1.00 29.75  ? 317 ILE B CG1 1 
ATOM   3951 C CG2 . ILE B 1 243 ? 135.167 113.041 123.377 1.00 35.29  ? 317 ILE B CG2 1 
ATOM   3952 C CD1 . ILE B 1 243 ? 132.388 113.886 124.113 1.00 38.50  ? 317 ILE B CD1 1 
ATOM   3953 N N   . VAL B 1 244 ? 137.797 112.920 126.923 1.00 24.67  ? 318 VAL B N   1 
ATOM   3954 C CA  . VAL B 1 244 ? 139.178 113.391 127.023 1.00 29.06  ? 318 VAL B CA  1 
ATOM   3955 C C   . VAL B 1 244 ? 139.896 113.161 125.696 1.00 26.06  ? 318 VAL B C   1 
ATOM   3956 O O   . VAL B 1 244 ? 139.932 112.041 125.176 1.00 30.96  ? 318 VAL B O   1 
ATOM   3957 C CB  . VAL B 1 244 ? 139.914 112.718 128.200 1.00 26.06  ? 318 VAL B CB  1 
ATOM   3958 C CG1 . VAL B 1 244 ? 139.888 111.204 128.074 1.00 30.11  ? 318 VAL B CG1 1 
ATOM   3959 C CG2 . VAL B 1 244 ? 141.348 113.211 128.276 1.00 30.22  ? 318 VAL B CG2 1 
ATOM   3960 N N   . SER B 1 245 ? 140.452 114.231 125.127 1.00 26.71  ? 319 SER B N   1 
ATOM   3961 C CA  . SER B 1 245 ? 140.788 114.244 123.710 1.00 18.61  ? 319 SER B CA  1 
ATOM   3962 C C   . SER B 1 245 ? 142.043 115.071 123.468 1.00 28.81  ? 319 SER B C   1 
ATOM   3963 O O   . SER B 1 245 ? 142.597 115.692 124.380 1.00 32.77  ? 319 SER B O   1 
ATOM   3964 C CB  . SER B 1 245 ? 139.627 114.801 122.881 1.00 22.60  ? 319 SER B CB  1 
ATOM   3965 O OG  . SER B 1 245 ? 139.691 116.213 122.794 1.00 33.37  ? 319 SER B OG  1 
ATOM   3966 N N   . THR B 1 246 ? 142.477 115.069 122.219 1.00 28.88  ? 320 THR B N   1 
ATOM   3967 C CA  . THR B 1 246 ? 143.548 115.896 121.690 1.00 20.55  ? 320 THR B CA  1 
ATOM   3968 C C   . THR B 1 246 ? 142.965 117.098 120.966 1.00 30.57  ? 320 THR B C   1 
ATOM   3969 O O   . THR B 1 246 ? 141.756 117.168 120.723 1.00 37.54  ? 320 THR B O   1 
ATOM   3970 C CB  . THR B 1 246 ? 144.415 115.076 120.731 1.00 25.71  ? 320 THR B CB  1 
ATOM   3971 O OG1 . THR B 1 246 ? 143.617 114.627 119.629 1.00 30.75  ? 320 THR B OG1 1 
ATOM   3972 C CG2 . THR B 1 246 ? 145.009 113.877 121.436 1.00 26.54  ? 320 THR B CG2 1 
ATOM   3973 N N   . PRO B 1 247 ? 143.795 118.087 120.617 1.00 23.26  ? 321 PRO B N   1 
ATOM   3974 C CA  . PRO B 1 247 ? 143.305 119.147 119.721 1.00 17.03  ? 321 PRO B CA  1 
ATOM   3975 C C   . PRO B 1 247 ? 142.787 118.613 118.398 1.00 29.46  ? 321 PRO B C   1 
ATOM   3976 O O   . PRO B 1 247 ? 141.797 119.134 117.868 1.00 30.94  ? 321 PRO B O   1 
ATOM   3977 C CB  . PRO B 1 247 ? 144.539 120.038 119.539 1.00 18.24  ? 321 PRO B CB  1 
ATOM   3978 C CG  . PRO B 1 247 ? 145.293 119.861 120.802 1.00 21.42  ? 321 PRO B CG  1 
ATOM   3979 C CD  . PRO B 1 247 ? 145.121 118.416 121.171 1.00 23.69  ? 321 PRO B CD  1 
ATOM   3980 N N   . THR B 1 248 ? 143.426 117.573 117.855 1.00 30.86  ? 322 THR B N   1 
ATOM   3981 C CA  . THR B 1 248 ? 142.938 116.955 116.626 1.00 23.02  ? 322 THR B CA  1 
ATOM   3982 C C   . THR B 1 248 ? 141.531 116.404 116.814 1.00 24.44  ? 322 THR B C   1 
ATOM   3983 O O   . THR B 1 248 ? 140.698 116.478 115.903 1.00 35.86  ? 322 THR B O   1 
ATOM   3984 C CB  . THR B 1 248 ? 143.896 115.849 116.180 1.00 24.72  ? 322 THR B CB  1 
ATOM   3985 O OG1 . THR B 1 248 ? 145.199 116.403 115.961 1.00 26.26  ? 322 THR B OG1 1 
ATOM   3986 C CG2 . THR B 1 248 ? 143.408 115.196 114.895 1.00 26.75  ? 322 THR B CG2 1 
ATOM   3987 N N   . GLY B 1 249 ? 141.244 115.863 117.992 1.00 12.87  ? 323 GLY B N   1 
ATOM   3988 C CA  . GLY B 1 249 ? 139.914 115.403 118.322 1.00 16.50  ? 323 GLY B CA  1 
ATOM   3989 C C   . GLY B 1 249 ? 138.968 116.479 118.792 1.00 23.53  ? 323 GLY B C   1 
ATOM   3990 O O   . GLY B 1 249 ? 137.838 116.170 119.179 1.00 32.13  ? 323 GLY B O   1 
ATOM   3991 N N   . SER B 1 250 ? 139.403 117.742 118.781 1.00 29.80  ? 324 SER B N   1 
ATOM   3992 C CA  . SER B 1 250 ? 138.520 118.835 119.174 1.00 25.47  ? 324 SER B CA  1 
ATOM   3993 C C   . SER B 1 250 ? 137.335 118.966 118.228 1.00 31.60  ? 324 SER B C   1 
ATOM   3994 O O   . SER B 1 250 ? 136.236 119.329 118.660 1.00 44.09  ? 324 SER B O   1 
ATOM   3995 C CB  . SER B 1 250 ? 139.300 120.147 119.231 1.00 32.53  ? 324 SER B CB  1 
ATOM   3996 O OG  . SER B 1 250 ? 139.544 120.650 117.930 1.00 34.06  ? 324 SER B OG  1 
ATOM   3997 N N   . THR B 1 251 ? 137.537 118.685 116.943 1.00 35.03  ? 325 THR B N   1 
ATOM   3998 C CA  . THR B 1 251 ? 136.470 118.700 115.950 1.00 32.23  ? 325 THR B CA  1 
ATOM   3999 C C   . THR B 1 251 ? 135.735 117.370 115.863 1.00 30.38  ? 325 THR B C   1 
ATOM   4000 O O   . THR B 1 251 ? 134.738 117.270 115.141 1.00 37.48  ? 325 THR B O   1 
ATOM   4001 C CB  . THR B 1 251 ? 137.037 119.060 114.575 1.00 28.12  ? 325 THR B CB  1 
ATOM   4002 O OG1 . THR B 1 251 ? 138.230 118.304 114.339 1.00 38.71  ? 325 THR B OG1 1 
ATOM   4003 C CG2 . THR B 1 251 ? 137.372 120.535 114.515 1.00 30.23  ? 325 THR B CG2 1 
ATOM   4004 N N   . ALA B 1 252 ? 136.209 116.356 116.582 1.00 32.52  ? 326 ALA B N   1 
ATOM   4005 C CA  . ALA B 1 252 ? 135.610 115.029 116.619 1.00 29.25  ? 326 ALA B CA  1 
ATOM   4006 C C   . ALA B 1 252 ? 134.446 114.989 117.599 1.00 35.12  ? 326 ALA B C   1 
ATOM   4007 O O   . ALA B 1 252 ? 133.883 116.030 117.950 1.00 40.80  ? 326 ALA B O   1 
ATOM   4008 C CB  . ALA B 1 252 ? 136.655 113.976 116.989 1.00 34.37  ? 326 ALA B CB  1 
ATOM   4009 N N   . TYR B 1 253 ? 134.070 113.780 118.018 1.00 31.76  ? 327 TYR B N   1 
ATOM   4010 C CA  . TYR B 1 253 ? 132.991 113.514 118.966 1.00 26.33  ? 327 TYR B CA  1 
ATOM   4011 C C   . TYR B 1 253 ? 132.967 114.490 120.138 1.00 29.97  ? 327 TYR B C   1 
ATOM   4012 O O   . TYR B 1 253 ? 131.905 114.736 120.720 1.00 40.88  ? 327 TYR B O   1 
ATOM   4013 C CB  . TYR B 1 253 ? 133.123 112.074 119.468 1.00 33.04  ? 327 TYR B CB  1 
ATOM   4014 C CG  . TYR B 1 253 ? 132.077 111.617 120.457 1.00 33.22  ? 327 TYR B CG  1 
ATOM   4015 C CD1 . TYR B 1 253 ? 130.743 111.533 120.096 1.00 41.05  ? 327 TYR B CD1 1 
ATOM   4016 C CD2 . TYR B 1 253 ? 132.436 111.204 121.730 1.00 35.06  ? 327 TYR B CD2 1 
ATOM   4017 C CE1 . TYR B 1 253 ? 129.787 111.095 120.985 1.00 36.56  ? 327 TYR B CE1 1 
ATOM   4018 C CE2 . TYR B 1 253 ? 131.487 110.761 122.627 1.00 36.07  ? 327 TYR B CE2 1 
ATOM   4019 C CZ  . TYR B 1 253 ? 130.164 110.709 122.249 1.00 38.13  ? 327 TYR B CZ  1 
ATOM   4020 O OH  . TYR B 1 253 ? 129.209 110.269 123.134 1.00 43.63  ? 327 TYR B OH  1 
ATOM   4021 N N   . ALA B 1 254 ? 134.126 115.043 120.501 1.00 34.50  ? 328 ALA B N   1 
ATOM   4022 C CA  . ALA B 1 254 ? 134.154 116.109 121.497 1.00 29.83  ? 328 ALA B CA  1 
ATOM   4023 C C   . ALA B 1 254 ? 133.362 117.325 121.030 1.00 32.42  ? 328 ALA B C   1 
ATOM   4024 O O   . ALA B 1 254 ? 132.611 117.921 121.810 1.00 38.19  ? 328 ALA B O   1 
ATOM   4025 C CB  . ALA B 1 254 ? 135.598 116.497 121.811 1.00 35.41  ? 328 ALA B CB  1 
ATOM   4026 N N   . ALA B 1 255 ? 133.511 117.707 119.757 1.00 27.79  ? 329 ALA B N   1 
ATOM   4027 C CA  . ALA B 1 255 ? 132.764 118.847 119.233 1.00 22.80  ? 329 ALA B CA  1 
ATOM   4028 C C   . ALA B 1 255 ? 131.266 118.585 119.228 1.00 31.26  ? 329 ALA B C   1 
ATOM   4029 O O   . ALA B 1 255 ? 130.472 119.525 119.345 1.00 39.02  ? 329 ALA B O   1 
ATOM   4030 C CB  . ALA B 1 255 ? 133.236 119.192 117.821 1.00 28.86  ? 329 ALA B CB  1 
ATOM   4031 N N   . ALA B 1 256 ? 130.861 117.322 119.088 1.00 33.39  ? 330 ALA B N   1 
ATOM   4032 C CA  . ALA B 1 256 ? 129.441 116.997 119.108 1.00 25.04  ? 330 ALA B CA  1 
ATOM   4033 C C   . ALA B 1 256 ? 128.821 117.263 120.472 1.00 33.84  ? 330 ALA B C   1 
ATOM   4034 O O   . ALA B 1 256 ? 127.630 117.581 120.559 1.00 40.79  ? 330 ALA B O   1 
ATOM   4035 C CB  . ALA B 1 256 ? 129.232 115.538 118.705 1.00 30.43  ? 330 ALA B CB  1 
ATOM   4036 N N   . ALA B 1 257 ? 129.608 117.156 121.539 1.00 33.24  ? 331 ALA B N   1 
ATOM   4037 C CA  . ALA B 1 257 ? 129.115 117.355 122.894 1.00 33.85  ? 331 ALA B CA  1 
ATOM   4038 C C   . ALA B 1 257 ? 129.229 118.798 123.368 1.00 34.31  ? 331 ALA B C   1 
ATOM   4039 O O   . ALA B 1 257 ? 128.933 119.075 124.535 1.00 40.68  ? 331 ALA B O   1 
ATOM   4040 C CB  . ALA B 1 257 ? 129.861 116.437 123.863 1.00 34.87  ? 331 ALA B CB  1 
ATOM   4041 N N   . GLY B 1 258 ? 129.648 119.717 122.504 1.00 30.46  ? 332 GLY B N   1 
ATOM   4042 C CA  . GLY B 1 258 ? 129.740 121.118 122.854 1.00 30.45  ? 332 GLY B CA  1 
ATOM   4043 C C   . GLY B 1 258 ? 131.137 121.654 123.084 1.00 31.48  ? 332 GLY B C   1 
ATOM   4044 O O   . GLY B 1 258 ? 131.271 122.803 123.521 1.00 38.53  ? 332 GLY B O   1 
ATOM   4045 N N   . ALA B 1 259 ? 132.175 120.871 122.811 1.00 34.62  ? 333 ALA B N   1 
ATOM   4046 C CA  . ALA B 1 259 ? 133.537 121.349 122.994 1.00 30.09  ? 333 ALA B CA  1 
ATOM   4047 C C   . ALA B 1 259 ? 133.919 122.331 121.892 1.00 34.71  ? 333 ALA B C   1 
ATOM   4048 O O   . ALA B 1 259 ? 133.420 122.265 120.766 1.00 43.91  ? 333 ALA B O   1 
ATOM   4049 C CB  . ALA B 1 259 ? 134.516 120.177 123.012 1.00 34.82  ? 333 ALA B CB  1 
ATOM   4050 N N   . SER B 1 260 ? 134.819 123.250 122.230 1.00 33.99  ? 334 SER B N   1 
ATOM   4051 C CA  . SER B 1 260 ? 135.299 124.236 121.277 1.00 27.08  ? 334 SER B CA  1 
ATOM   4052 C C   . SER B 1 260 ? 136.354 123.628 120.357 1.00 34.11  ? 334 SER B C   1 
ATOM   4053 O O   . SER B 1 260 ? 136.977 122.610 120.669 1.00 36.88  ? 334 SER B O   1 
ATOM   4054 C CB  . SER B 1 260 ? 135.879 125.449 122.005 1.00 30.43  ? 334 SER B CB  1 
ATOM   4055 O OG  . SER B 1 260 ? 135.010 125.890 123.033 1.00 40.37  ? 334 SER B OG  1 
ATOM   4056 N N   . MET B 1 261 ? 136.548 124.266 119.206 1.00 35.21  ? 335 MET B N   1 
ATOM   4057 C CA  . MET B 1 261 ? 137.591 123.844 118.282 1.00 30.33  ? 335 MET B CA  1 
ATOM   4058 C C   . MET B 1 261 ? 138.933 124.417 118.716 1.00 34.64  ? 335 MET B C   1 
ATOM   4059 O O   . MET B 1 261 ? 139.056 125.621 118.960 1.00 33.04  ? 335 MET B O   1 
ATOM   4060 C CB  . MET B 1 261 ? 137.276 124.284 116.853 1.00 36.00  ? 335 MET B CB  1 
ATOM   4061 C CG  . MET B 1 261 ? 136.224 123.449 116.149 1.00 43.98  ? 335 MET B CG  1 
ATOM   4062 S SD  . MET B 1 261 ? 134.557 123.748 116.741 1.00 46.57  ? 335 MET B SD  1 
ATOM   4063 C CE  . MET B 1 261 ? 134.266 125.344 115.990 1.00 36.72  ? 335 MET B CE  1 
ATOM   4064 N N   . ILE B 1 262 ? 139.938 123.551 118.810 1.00 36.04  ? 336 ILE B N   1 
ATOM   4065 C CA  . ILE B 1 262 ? 141.300 123.949 119.142 1.00 30.13  ? 336 ILE B CA  1 
ATOM   4066 C C   . ILE B 1 262 ? 142.207 123.561 117.985 1.00 30.98  ? 336 ILE B C   1 
ATOM   4067 O O   . ILE B 1 262 ? 142.174 122.417 117.520 1.00 38.58  ? 336 ILE B O   1 
ATOM   4068 C CB  . ILE B 1 262 ? 141.780 123.309 120.458 1.00 27.61  ? 336 ILE B CB  1 
ATOM   4069 C CG1 . ILE B 1 262 ? 140.952 123.827 121.632 1.00 31.25  ? 336 ILE B CG1 1 
ATOM   4070 C CG2 . ILE B 1 262 ? 143.254 123.587 120.683 1.00 32.53  ? 336 ILE B CG2 1 
ATOM   4071 C CD1 . ILE B 1 262 ? 141.222 123.111 122.926 1.00 36.20  ? 336 ILE B CD1 1 
ATOM   4072 N N   . HIS B 1 263 ? 143.004 124.517 117.521 1.00 27.99  ? 337 HIS B N   1 
ATOM   4073 C CA  . HIS B 1 263 ? 143.928 124.257 116.430 1.00 19.72  ? 337 HIS B CA  1 
ATOM   4074 C C   . HIS B 1 263 ? 144.946 123.200 116.855 1.00 26.86  ? 337 HIS B C   1 
ATOM   4075 O O   . HIS B 1 263 ? 145.403 123.206 118.004 1.00 38.67  ? 337 HIS B O   1 
ATOM   4076 C CB  . HIS B 1 263 ? 144.635 125.552 116.025 1.00 25.14  ? 337 HIS B CB  1 
ATOM   4077 C CG  . HIS B 1 263 ? 145.354 125.473 114.714 1.00 23.60  ? 337 HIS B CG  1 
ATOM   4078 N ND1 . HIS B 1 263 ? 146.538 124.785 114.553 1.00 31.36  ? 337 HIS B ND1 1 
ATOM   4079 C CD2 . HIS B 1 263 ? 145.059 126.000 113.503 1.00 21.00  ? 337 HIS B CD2 1 
ATOM   4080 C CE1 . HIS B 1 263 ? 146.938 124.890 113.299 1.00 31.72  ? 337 HIS B CE1 1 
ATOM   4081 N NE2 . HIS B 1 263 ? 146.059 125.622 112.641 1.00 32.87  ? 337 HIS B NE2 1 
ATOM   4082 N N   . PRO B 1 264 ? 145.318 122.277 115.963 1.00 27.52  ? 338 PRO B N   1 
ATOM   4083 C CA  . PRO B 1 264 ? 146.262 121.214 116.348 1.00 25.82  ? 338 PRO B CA  1 
ATOM   4084 C C   . PRO B 1 264 ? 147.643 121.715 116.743 1.00 23.85  ? 338 PRO B C   1 
ATOM   4085 O O   . PRO B 1 264 ? 148.469 120.902 117.177 1.00 32.33  ? 338 PRO B O   1 
ATOM   4086 C CB  . PRO B 1 264 ? 146.329 120.333 115.092 1.00 26.24  ? 338 PRO B CB  1 
ATOM   4087 C CG  . PRO B 1 264 ? 145.857 121.219 113.982 1.00 19.57  ? 338 PRO B CG  1 
ATOM   4088 C CD  . PRO B 1 264 ? 144.797 122.069 114.603 1.00 31.10  ? 338 PRO B CD  1 
ATOM   4089 N N   . ASN B 1 265 ? 147.922 123.008 116.610 1.00 20.78  ? 339 ASN B N   1 
ATOM   4090 C CA  . ASN B 1 265 ? 149.195 123.577 117.030 1.00 23.15  ? 339 ASN B CA  1 
ATOM   4091 C C   . ASN B 1 265 ? 149.162 124.112 118.456 1.00 29.37  ? 339 ASN B C   1 
ATOM   4092 O O   . ASN B 1 265 ? 150.156 124.688 118.908 1.00 35.21  ? 339 ASN B O   1 
ATOM   4093 C CB  . ASN B 1 265 ? 149.613 124.694 116.070 1.00 32.29  ? 339 ASN B CB  1 
ATOM   4094 C CG  . ASN B 1 265 ? 150.527 124.203 114.966 1.00 30.74  ? 339 ASN B CG  1 
ATOM   4095 O OD1 . ASN B 1 265 ? 150.859 123.020 114.899 1.00 34.15  ? 339 ASN B OD1 1 
ATOM   4096 N ND2 . ASN B 1 265 ? 150.939 125.112 114.091 1.00 32.62  ? 339 ASN B ND2 1 
ATOM   4097 N N   . VAL B 1 266 ? 148.052 123.938 119.168 1.00 31.64  ? 340 VAL B N   1 
ATOM   4098 C CA  . VAL B 1 266 ? 147.906 124.415 120.540 1.00 21.79  ? 340 VAL B CA  1 
ATOM   4099 C C   . VAL B 1 266 ? 148.101 123.220 121.471 1.00 32.92  ? 340 VAL B C   1 
ATOM   4100 O O   . VAL B 1 266 ? 147.273 122.294 121.451 1.00 41.58  ? 340 VAL B O   1 
ATOM   4101 C CB  . VAL B 1 266 ? 146.540 125.073 120.766 1.00 18.31  ? 340 VAL B CB  1 
ATOM   4102 C CG1 . VAL B 1 266 ? 146.449 125.640 122.171 1.00 26.91  ? 340 VAL B CG1 1 
ATOM   4103 C CG2 . VAL B 1 266 ? 146.294 126.154 119.729 1.00 26.47  ? 340 VAL B CG2 1 
ATOM   4104 N N   . PRO B 1 267 ? 149.154 123.191 122.288 1.00 28.68  ? 341 PRO B N   1 
ATOM   4105 C CA  . PRO B 1 267 ? 149.358 122.048 123.189 1.00 26.78  ? 341 PRO B CA  1 
ATOM   4106 C C   . PRO B 1 267 ? 148.409 122.052 124.379 1.00 27.04  ? 341 PRO B C   1 
ATOM   4107 O O   . PRO B 1 267 ? 148.558 122.862 125.299 1.00 33.06  ? 341 PRO B O   1 
ATOM   4108 C CB  . PRO B 1 267 ? 150.816 122.216 123.632 1.00 25.37  ? 341 PRO B CB  1 
ATOM   4109 C CG  . PRO B 1 267 ? 151.055 123.687 123.534 1.00 22.28  ? 341 PRO B CG  1 
ATOM   4110 C CD  . PRO B 1 267 ? 150.290 124.128 122.321 1.00 24.11  ? 341 PRO B CD  1 
ATOM   4111 N N   . ALA B 1 268 ? 147.433 121.146 124.372 1.00 21.85  ? 342 ALA B N   1 
ATOM   4112 C CA  . ALA B 1 268 ? 146.480 121.039 125.467 1.00 14.94  ? 342 ALA B CA  1 
ATOM   4113 C C   . ALA B 1 268 ? 145.797 119.682 125.403 1.00 24.21  ? 342 ALA B C   1 
ATOM   4114 O O   . ALA B 1 268 ? 145.843 118.990 124.383 1.00 34.42  ? 342 ALA B O   1 
ATOM   4115 C CB  . ALA B 1 268 ? 145.441 122.164 125.423 1.00 26.74  ? 342 ALA B CB  1 
ATOM   4116 N N   . ILE B 1 269 ? 145.162 119.312 126.512 1.00 29.02  ? 343 ILE B N   1 
ATOM   4117 C CA  . ILE B 1 269 ? 144.330 118.118 126.600 1.00 21.56  ? 343 ILE B CA  1 
ATOM   4118 C C   . ILE B 1 269 ? 142.929 118.557 126.996 1.00 30.52  ? 343 ILE B C   1 
ATOM   4119 O O   . ILE B 1 269 ? 142.757 119.277 127.985 1.00 38.38  ? 343 ILE B O   1 
ATOM   4120 C CB  . ILE B 1 269 ? 144.885 117.100 127.613 1.00 21.24  ? 343 ILE B CB  1 
ATOM   4121 C CG1 . ILE B 1 269 ? 146.317 116.701 127.256 1.00 32.09  ? 343 ILE B CG1 1 
ATOM   4122 C CG2 . ILE B 1 269 ? 143.995 115.871 127.674 1.00 29.75  ? 343 ILE B CG2 1 
ATOM   4123 C CD1 . ILE B 1 269 ? 146.946 115.766 128.262 1.00 28.65  ? 343 ILE B CD1 1 
ATOM   4124 N N   . MET B 1 270 ? 141.932 118.122 126.237 1.00 29.81  ? 344 MET B N   1 
ATOM   4125 C CA  . MET B 1 270 ? 140.563 118.552 126.470 1.00 20.52  ? 344 MET B CA  1 
ATOM   4126 C C   . MET B 1 270 ? 139.822 117.539 127.331 1.00 26.81  ? 344 MET B C   1 
ATOM   4127 O O   . MET B 1 270 ? 140.102 116.340 127.290 1.00 36.58  ? 344 MET B O   1 
ATOM   4128 C CB  . MET B 1 270 ? 139.825 118.737 125.145 1.00 30.10  ? 344 MET B CB  1 
ATOM   4129 C CG  . MET B 1 270 ? 140.124 120.048 124.453 1.00 37.81  ? 344 MET B CG  1 
ATOM   4130 S SD  . MET B 1 270 ? 139.179 120.251 122.935 1.00 60.71  ? 344 MET B SD  1 
ATOM   4131 C CE  . MET B 1 270 ? 137.853 121.297 123.523 1.00 38.63  ? 344 MET B CE  1 
ATOM   4132 N N   . ILE B 1 271 ? 138.878 118.037 128.125 1.00 25.57  ? 345 ILE B N   1 
ATOM   4133 C CA  . ILE B 1 271 ? 137.948 117.202 128.875 1.00 22.71  ? 345 ILE B CA  1 
ATOM   4134 C C   . ILE B 1 271 ? 136.544 117.708 128.582 1.00 29.83  ? 345 ILE B C   1 
ATOM   4135 O O   . ILE B 1 271 ? 136.213 118.856 128.905 1.00 33.87  ? 345 ILE B O   1 
ATOM   4136 C CB  . ILE B 1 271 ? 138.229 117.221 130.387 1.00 24.18  ? 345 ILE B CB  1 
ATOM   4137 C CG1 . ILE B 1 271 ? 139.604 116.623 130.687 1.00 25.38  ? 345 ILE B CG1 1 
ATOM   4138 C CG2 . ILE B 1 271 ? 137.149 116.458 131.136 1.00 30.93  ? 345 ILE B CG2 1 
ATOM   4139 C CD1 . ILE B 1 271 ? 140.254 117.188 131.926 1.00 31.84  ? 345 ILE B CD1 1 
ATOM   4140 N N   . THR B 1 272 ? 135.723 116.855 127.969 1.00 33.60  ? 346 THR B N   1 
ATOM   4141 C CA  . THR B 1 272 ? 134.377 117.210 127.550 1.00 31.59  ? 346 THR B CA  1 
ATOM   4142 C C   . THR B 1 272 ? 133.415 116.119 128.004 1.00 30.59  ? 346 THR B C   1 
ATOM   4143 O O   . THR B 1 272 ? 133.719 114.923 127.848 1.00 34.81  ? 346 THR B O   1 
ATOM   4144 C CB  . THR B 1 272 ? 134.304 117.387 126.025 1.00 29.67  ? 346 THR B CB  1 
ATOM   4145 O OG1 . THR B 1 272 ? 135.446 118.124 125.571 1.00 36.77  ? 346 THR B OG1 1 
ATOM   4146 C CG2 . THR B 1 272 ? 133.037 118.127 125.623 1.00 32.31  ? 346 THR B CG2 1 
ATOM   4147 N N   . PRO B 1 273 ? 132.264 116.473 128.561 1.00 30.09  ? 347 PRO B N   1 
ATOM   4148 C CA  . PRO B 1 273 ? 131.285 115.469 128.983 1.00 31.55  ? 347 PRO B CA  1 
ATOM   4149 C C   . PRO B 1 273 ? 130.527 114.902 127.790 1.00 31.95  ? 347 PRO B C   1 
ATOM   4150 O O   . PRO B 1 273 ? 130.798 115.219 126.635 1.00 41.12  ? 347 PRO B O   1 
ATOM   4151 C CB  . PRO B 1 273 ? 130.348 116.266 129.884 1.00 31.71  ? 347 PRO B CB  1 
ATOM   4152 C CG  . PRO B 1 273 ? 130.383 117.634 129.293 1.00 33.91  ? 347 PRO B CG  1 
ATOM   4153 C CD  . PRO B 1 273 ? 131.822 117.836 128.902 1.00 33.63  ? 347 PRO B CD  1 
ATOM   4154 N N   . ILE B 1 274 ? 129.559 114.045 128.099 1.00 29.03  ? 348 ILE B N   1 
ATOM   4155 C CA  . ILE B 1 274 ? 128.594 113.549 127.120 1.00 29.14  ? 348 ILE B CA  1 
ATOM   4156 C C   . ILE B 1 274 ? 127.230 113.696 127.788 1.00 36.74  ? 348 ILE B C   1 
ATOM   4157 O O   . ILE B 1 274 ? 126.793 112.817 128.536 1.00 44.63  ? 348 ILE B O   1 
ATOM   4158 C CB  . ILE B 1 274 ? 128.851 112.097 126.713 1.00 33.04  ? 348 ILE B CB  1 
ATOM   4159 C CG1 . ILE B 1 274 ? 130.247 111.937 126.131 1.00 30.92  ? 348 ILE B CG1 1 
ATOM   4160 C CG2 . ILE B 1 274 ? 127.843 111.676 125.659 1.00 39.45  ? 348 ILE B CG2 1 
ATOM   4161 C CD1 . ILE B 1 274 ? 130.692 110.500 126.012 1.00 34.65  ? 348 ILE B CD1 1 
ATOM   4162 N N   . CYS B 1 275 ? 126.555 114.813 127.529 1.00 37.53  ? 349 CYS B N   1 
ATOM   4163 C CA  . CYS B 1 275 ? 125.249 115.095 128.113 1.00 35.37  ? 349 CYS B CA  1 
ATOM   4164 C C   . CYS B 1 275 ? 125.286 114.941 129.630 1.00 34.93  ? 349 CYS B C   1 
ATOM   4165 O O   . CYS B 1 275 ? 124.632 114.042 130.175 1.00 40.67  ? 349 CYS B O   1 
ATOM   4166 C CB  . CYS B 1 275 ? 124.186 114.173 127.513 1.00 33.75  ? 349 CYS B CB  1 
ATOM   4167 S SG  . CYS B 1 275 ? 124.189 114.109 125.708 1.00 47.48  ? 349 CYS B SG  1 
ATOM   4168 N N   . PRO B 1 276 ? 126.039 115.775 130.343 1.00 31.85  ? 350 PRO B N   1 
ATOM   4169 C CA  . PRO B 1 276 ? 126.104 115.636 131.800 1.00 27.81  ? 350 PRO B CA  1 
ATOM   4170 C C   . PRO B 1 276 ? 124.785 116.009 132.453 1.00 36.88  ? 350 PRO B C   1 
ATOM   4171 O O   . PRO B 1 276 ? 124.043 116.866 131.967 1.00 45.06  ? 350 PRO B O   1 
ATOM   4172 C CB  . PRO B 1 276 ? 127.216 116.610 132.196 1.00 33.75  ? 350 PRO B CB  1 
ATOM   4173 C CG  . PRO B 1 276 ? 127.152 117.665 131.154 1.00 36.74  ? 350 PRO B CG  1 
ATOM   4174 C CD  . PRO B 1 276 ? 126.756 116.973 129.875 1.00 37.78  ? 350 PRO B CD  1 
ATOM   4175 N N   . HIS B 1 277 ? 124.498 115.359 133.580 1.00 40.63  ? 351 HIS B N   1 
ATOM   4176 C CA  . HIS B 1 277 ? 123.285 115.671 134.324 1.00 38.88  ? 351 HIS B CA  1 
ATOM   4177 C C   . HIS B 1 277 ? 123.543 116.865 135.234 1.00 39.42  ? 351 HIS B C   1 
ATOM   4178 O O   . HIS B 1 277 ? 123.273 116.817 136.438 1.00 41.01  ? 351 HIS B O   1 
ATOM   4179 C CB  . HIS B 1 277 ? 122.813 114.460 135.130 1.00 44.36  ? 351 HIS B CB  1 
ATOM   4180 C CG  . HIS B 1 277 ? 121.428 114.602 135.679 1.00 51.99  ? 351 HIS B CG  1 
ATOM   4181 N ND1 . HIS B 1 277 ? 120.924 113.768 136.654 1.00 54.01  ? 351 HIS B ND1 1 
ATOM   4182 C CD2 . HIS B 1 277 ? 120.439 115.480 135.386 1.00 46.89  ? 351 HIS B CD2 1 
ATOM   4183 C CE1 . HIS B 1 277 ? 119.685 114.128 136.940 1.00 49.18  ? 351 HIS B CE1 1 
ATOM   4184 N NE2 . HIS B 1 277 ? 119.367 115.163 136.184 1.00 47.63  ? 351 HIS B NE2 1 
ATOM   4185 N N   . SER B 1 278 ? 124.073 117.939 134.655 1.00 40.88  ? 352 SER B N   1 
ATOM   4186 C CA  . SER B 1 278 ? 124.378 119.163 135.378 1.00 34.96  ? 352 SER B CA  1 
ATOM   4187 C C   . SER B 1 278 ? 124.456 120.293 134.366 1.00 38.75  ? 352 SER B C   1 
ATOM   4188 O O   . SER B 1 278 ? 124.981 120.109 133.266 1.00 46.88  ? 352 SER B O   1 
ATOM   4189 C CB  . SER B 1 278 ? 125.692 119.048 136.157 1.00 35.09  ? 352 SER B CB  1 
ATOM   4190 O OG  . SER B 1 278 ? 126.000 120.263 136.817 1.00 40.67  ? 352 SER B OG  1 
ATOM   4191 N N   . LEU B 1 279 ? 123.933 121.455 134.742 1.00 28.40  ? 353 LEU B N   1 
ATOM   4192 C CA  . LEU B 1 279 ? 123.892 122.590 133.835 1.00 33.14  ? 353 LEU B CA  1 
ATOM   4193 C C   . LEU B 1 279 ? 125.193 123.380 133.798 1.00 37.33  ? 353 LEU B C   1 
ATOM   4194 O O   . LEU B 1 279 ? 125.335 124.262 132.944 1.00 38.36  ? 353 LEU B O   1 
ATOM   4195 C CB  . LEU B 1 279 ? 122.742 123.528 134.219 1.00 37.34  ? 353 LEU B CB  1 
ATOM   4196 C CG  . LEU B 1 279 ? 121.380 122.877 134.475 1.00 35.11  ? 353 LEU B CG  1 
ATOM   4197 C CD1 . LEU B 1 279 ? 120.359 123.917 134.906 1.00 38.81  ? 353 LEU B CD1 1 
ATOM   4198 C CD2 . LEU B 1 279 ? 120.894 122.125 133.249 1.00 34.49  ? 353 LEU B CD2 1 
ATOM   4199 N N   . SER B 1 280 ? 126.151 123.083 134.680 1.00 41.61  ? 354 SER B N   1 
ATOM   4200 C CA  . SER B 1 280 ? 127.342 123.912 134.830 1.00 36.31  ? 354 SER B CA  1 
ATOM   4201 C C   . SER B 1 280 ? 128.644 123.143 134.639 1.00 38.61  ? 354 SER B C   1 
ATOM   4202 O O   . SER B 1 280 ? 129.685 123.579 135.139 1.00 44.60  ? 354 SER B O   1 
ATOM   4203 C CB  . SER B 1 280 ? 127.348 124.593 136.199 1.00 39.11  ? 354 SER B CB  1 
ATOM   4204 O OG  . SER B 1 280 ? 127.433 123.642 137.239 1.00 41.64  ? 354 SER B OG  1 
ATOM   4205 N N   . PHE B 1 281 ? 128.626 122.014 133.933 1.00 35.45  ? 355 PHE B N   1 
ATOM   4206 C CA  . PHE B 1 281 ? 129.859 121.266 133.697 1.00 33.88  ? 355 PHE B CA  1 
ATOM   4207 C C   . PHE B 1 281 ? 130.357 121.637 132.302 1.00 32.97  ? 355 PHE B C   1 
ATOM   4208 O O   . PHE B 1 281 ? 130.220 120.890 131.334 1.00 41.12  ? 355 PHE B O   1 
ATOM   4209 C CB  . PHE B 1 281 ? 129.636 119.765 133.856 1.00 32.42  ? 355 PHE B CB  1 
ATOM   4210 C CG  . PHE B 1 281 ? 130.885 118.947 133.679 1.00 39.23  ? 355 PHE B CG  1 
ATOM   4211 C CD1 . PHE B 1 281 ? 131.836 118.898 134.680 1.00 43.32  ? 355 PHE B CD1 1 
ATOM   4212 C CD2 . PHE B 1 281 ? 131.114 118.234 132.525 1.00 40.48  ? 355 PHE B CD2 1 
ATOM   4213 C CE1 . PHE B 1 281 ? 132.984 118.148 134.534 1.00 39.91  ? 355 PHE B CE1 1 
ATOM   4214 C CE2 . PHE B 1 281 ? 132.267 117.486 132.372 1.00 37.63  ? 355 PHE B CE2 1 
ATOM   4215 C CZ  . PHE B 1 281 ? 133.201 117.445 133.376 1.00 36.57  ? 355 PHE B CZ  1 
ATOM   4216 N N   . ARG B 1 282 ? 130.929 122.833 132.209 1.00 32.32  ? 356 ARG B N   1 
ATOM   4217 C CA  . ARG B 1 282 ? 131.481 123.307 130.950 1.00 21.83  ? 356 ARG B CA  1 
ATOM   4218 C C   . ARG B 1 282 ? 132.758 122.539 130.615 1.00 35.33  ? 356 ARG B C   1 
ATOM   4219 O O   . ARG B 1 282 ? 133.562 122.252 131.508 1.00 46.33  ? 356 ARG B O   1 
ATOM   4220 C CB  . ARG B 1 282 ? 131.768 124.807 131.036 1.00 26.02  ? 356 ARG B CB  1 
ATOM   4221 C CG  . ARG B 1 282 ? 132.047 125.487 129.708 1.00 35.26  ? 356 ARG B CG  1 
ATOM   4222 C CD  . ARG B 1 282 ? 130.766 125.791 128.950 1.00 38.16  ? 356 ARG B CD  1 
ATOM   4223 N NE  . ARG B 1 282 ? 129.827 126.584 129.734 1.00 37.27  ? 356 ARG B NE  1 
ATOM   4224 C CZ  . ARG B 1 282 ? 129.673 127.895 129.613 1.00 31.94  ? 356 ARG B CZ  1 
ATOM   4225 N NH1 . ARG B 1 282 ? 130.408 128.603 128.773 1.00 33.81  ? 356 ARG B NH1 1 
ATOM   4226 N NH2 . ARG B 1 282 ? 128.757 128.512 130.355 1.00 36.24  ? 356 ARG B NH2 1 
ATOM   4227 N N   . PRO B 1 283 ? 132.967 122.179 129.346 1.00 33.18  ? 357 PRO B N   1 
ATOM   4228 C CA  . PRO B 1 283 ? 134.207 121.489 128.973 1.00 30.34  ? 357 PRO B CA  1 
ATOM   4229 C C   . PRO B 1 283 ? 135.432 122.344 129.262 1.00 26.90  ? 357 PRO B C   1 
ATOM   4230 O O   . PRO B 1 283 ? 135.401 123.571 129.156 1.00 28.40  ? 357 PRO B O   1 
ATOM   4231 C CB  . PRO B 1 283 ? 134.035 121.240 127.469 1.00 32.23  ? 357 PRO B CB  1 
ATOM   4232 C CG  . PRO B 1 283 ? 133.006 122.236 127.035 1.00 27.97  ? 357 PRO B CG  1 
ATOM   4233 C CD  . PRO B 1 283 ? 132.067 122.337 128.193 1.00 30.89  ? 357 PRO B CD  1 
ATOM   4234 N N   . ILE B 1 284 ? 136.522 121.675 129.633 1.00 26.75  ? 358 ILE B N   1 
ATOM   4235 C CA  . ILE B 1 284 ? 137.726 122.344 130.106 1.00 25.74  ? 358 ILE B CA  1 
ATOM   4236 C C   . ILE B 1 284 ? 138.913 121.891 129.262 1.00 29.40  ? 358 ILE B C   1 
ATOM   4237 O O   . ILE B 1 284 ? 138.853 120.894 128.544 1.00 36.00  ? 358 ILE B O   1 
ATOM   4238 C CB  . ILE B 1 284 ? 137.995 122.072 131.598 1.00 26.23  ? 358 ILE B CB  1 
ATOM   4239 C CG1 . ILE B 1 284 ? 138.263 120.586 131.824 1.00 27.97  ? 358 ILE B CG1 1 
ATOM   4240 C CG2 . ILE B 1 284 ? 136.811 122.507 132.442 1.00 30.55  ? 358 ILE B CG2 1 
ATOM   4241 C CD1 . ILE B 1 284 ? 138.362 120.195 133.280 1.00 32.34  ? 358 ILE B CD1 1 
ATOM   4242 N N   . VAL B 1 285 ? 140.005 122.653 129.353 1.00 29.96  ? 359 VAL B N   1 
ATOM   4243 C CA  . VAL B 1 285 ? 141.284 122.236 128.798 1.00 33.51  ? 359 VAL B CA  1 
ATOM   4244 C C   . VAL B 1 285 ? 142.315 122.274 129.917 1.00 34.91  ? 359 VAL B C   1 
ATOM   4245 O O   . VAL B 1 285 ? 142.178 123.006 130.901 1.00 41.09  ? 359 VAL B O   1 
ATOM   4246 C CB  . VAL B 1 285 ? 141.757 123.110 127.616 1.00 25.78  ? 359 VAL B CB  1 
ATOM   4247 C CG1 . VAL B 1 285 ? 140.668 123.234 126.560 1.00 26.37  ? 359 VAL B CG1 1 
ATOM   4248 C CG2 . VAL B 1 285 ? 142.254 124.455 128.103 1.00 31.38  ? 359 VAL B CG2 1 
ATOM   4249 N N   . VAL B 1 286 ? 143.351 121.459 129.758 1.00 27.08  ? 360 VAL B N   1 
ATOM   4250 C CA  . VAL B 1 286 ? 144.433 121.356 130.734 1.00 21.36  ? 360 VAL B CA  1 
ATOM   4251 C C   . VAL B 1 286 ? 145.759 121.323 129.993 1.00 26.91  ? 360 VAL B C   1 
ATOM   4252 O O   . VAL B 1 286 ? 145.816 120.974 128.805 1.00 36.90  ? 360 VAL B O   1 
ATOM   4253 C CB  . VAL B 1 286 ? 144.288 120.104 131.625 1.00 24.26  ? 360 VAL B CB  1 
ATOM   4254 C CG1 . VAL B 1 286 ? 142.977 120.142 132.393 1.00 23.51  ? 360 VAL B CG1 1 
ATOM   4255 C CG2 . VAL B 1 286 ? 144.367 118.846 130.784 1.00 33.38  ? 360 VAL B CG2 1 
ATOM   4256 N N   . PRO B 1 287 ? 146.846 121.706 130.664 1.00 24.93  ? 361 PRO B N   1 
ATOM   4257 C CA  . PRO B 1 287 ? 148.161 121.659 130.015 1.00 25.87  ? 361 PRO B CA  1 
ATOM   4258 C C   . PRO B 1 287 ? 148.524 120.245 129.591 1.00 25.74  ? 361 PRO B C   1 
ATOM   4259 O O   . PRO B 1 287 ? 148.132 119.262 130.221 1.00 33.41  ? 361 PRO B O   1 
ATOM   4260 C CB  . PRO B 1 287 ? 149.109 122.180 131.100 1.00 25.33  ? 361 PRO B CB  1 
ATOM   4261 C CG  . PRO B 1 287 ? 148.249 123.032 131.959 1.00 18.89  ? 361 PRO B CG  1 
ATOM   4262 C CD  . PRO B 1 287 ? 146.917 122.349 131.988 1.00 22.62  ? 361 PRO B CD  1 
ATOM   4263 N N   . ALA B 1 288 ? 149.280 120.154 128.495 1.00 25.23  ? 362 ALA B N   1 
ATOM   4264 C CA  . ALA B 1 288 ? 149.646 118.854 127.948 1.00 21.26  ? 362 ALA B CA  1 
ATOM   4265 C C   . ALA B 1 288 ? 150.534 118.052 128.890 1.00 24.25  ? 362 ALA B C   1 
ATOM   4266 O O   . ALA B 1 288 ? 150.602 116.826 128.764 1.00 37.03  ? 362 ALA B O   1 
ATOM   4267 C CB  . ALA B 1 288 ? 150.346 119.030 126.601 1.00 28.66  ? 362 ALA B CB  1 
ATOM   4268 N N   . GLY B 1 289 ? 151.206 118.708 129.831 1.00 25.92  ? 363 GLY B N   1 
ATOM   4269 C CA  . GLY B 1 289 ? 152.115 118.024 130.725 1.00 24.30  ? 363 GLY B CA  1 
ATOM   4270 C C   . GLY B 1 289 ? 151.495 117.359 131.931 1.00 25.84  ? 363 GLY B C   1 
ATOM   4271 O O   . GLY B 1 289 ? 152.223 116.772 132.736 1.00 36.25  ? 363 GLY B O   1 
ATOM   4272 N N   . VAL B 1 290 ? 150.175 117.428 132.091 1.00 28.15  ? 364 VAL B N   1 
ATOM   4273 C CA  . VAL B 1 290 ? 149.519 116.861 133.265 1.00 26.58  ? 364 VAL B CA  1 
ATOM   4274 C C   . VAL B 1 290 ? 149.221 115.387 133.028 1.00 19.87  ? 364 VAL B C   1 
ATOM   4275 O O   . VAL B 1 290 ? 149.274 114.903 131.892 1.00 31.49  ? 364 VAL B O   1 
ATOM   4276 C CB  . VAL B 1 290 ? 148.228 117.623 133.616 1.00 23.48  ? 364 VAL B CB  1 
ATOM   4277 C CG1 . VAL B 1 290 ? 148.516 119.104 133.817 1.00 29.85  ? 364 VAL B CG1 1 
ATOM   4278 C CG2 . VAL B 1 290 ? 147.172 117.399 132.552 1.00 22.89  ? 364 VAL B CG2 1 
ATOM   4279 N N   . GLU B 1 291 ? 148.908 114.668 134.102 1.00 25.64  ? 365 GLU B N   1 
ATOM   4280 C CA  . GLU B 1 291 ? 148.523 113.265 134.039 1.00 23.22  ? 365 GLU B CA  1 
ATOM   4281 C C   . GLU B 1 291 ? 147.095 113.117 134.541 1.00 25.37  ? 365 GLU B C   1 
ATOM   4282 O O   . GLU B 1 291 ? 146.776 113.549 135.654 1.00 37.01  ? 365 GLU B O   1 
ATOM   4283 C CB  . GLU B 1 291 ? 149.469 112.396 134.871 1.00 25.50  ? 365 GLU B CB  1 
ATOM   4284 C CG  . GLU B 1 291 ? 149.115 110.919 134.874 1.00 31.60  ? 365 GLU B CG  1 
ATOM   4285 C CD  . GLU B 1 291 ? 150.340 110.026 134.863 1.00 38.41  ? 365 GLU B CD  1 
ATOM   4286 O OE1 . GLU B 1 291 ? 151.262 110.271 135.668 1.00 40.36  ? 365 GLU B OE1 1 
ATOM   4287 O OE2 . GLU B 1 291 ? 150.379 109.078 134.052 1.00 35.76  ? 365 GLU B OE2 1 
ATOM   4288 N N   . LEU B 1 292 ? 146.242 112.510 133.724 1.00 20.71  ? 366 LEU B N   1 
ATOM   4289 C CA  . LEU B 1 292 ? 144.855 112.259 134.083 1.00 14.99  ? 366 LEU B CA  1 
ATOM   4290 C C   . LEU B 1 292 ? 144.683 110.804 134.496 1.00 23.71  ? 366 LEU B C   1 
ATOM   4291 O O   . LEU B 1 292 ? 145.339 109.909 133.962 1.00 34.56  ? 366 LEU B O   1 
ATOM   4292 C CB  . LEU B 1 292 ? 143.919 112.583 132.917 1.00 23.21  ? 366 LEU B CB  1 
ATOM   4293 C CG  . LEU B 1 292 ? 143.280 113.973 132.890 1.00 18.14  ? 366 LEU B CG  1 
ATOM   4294 C CD1 . LEU B 1 292 ? 144.336 115.063 132.927 1.00 25.33  ? 366 LEU B CD1 1 
ATOM   4295 C CD2 . LEU B 1 292 ? 142.398 114.126 131.665 1.00 26.74  ? 366 LEU B CD2 1 
ATOM   4296 N N   . LYS B 1 293 ? 143.792 110.572 135.458 1.00 24.29  ? 367 LYS B N   1 
ATOM   4297 C CA  . LYS B 1 293 ? 143.545 109.226 135.969 1.00 19.46  ? 367 LYS B CA  1 
ATOM   4298 C C   . LYS B 1 293 ? 142.051 109.075 136.219 1.00 24.90  ? 367 LYS B C   1 
ATOM   4299 O O   . LYS B 1 293 ? 141.497 109.728 137.104 1.00 36.13  ? 367 LYS B O   1 
ATOM   4300 C CB  . LYS B 1 293 ? 144.350 108.968 137.242 1.00 25.97  ? 367 LYS B CB  1 
ATOM   4301 C CG  . LYS B 1 293 ? 144.224 107.561 137.796 1.00 27.31  ? 367 LYS B CG  1 
ATOM   4302 C CD  . LYS B 1 293 ? 145.101 107.390 139.024 1.00 31.04  ? 367 LYS B CD  1 
ATOM   4303 C CE  . LYS B 1 293 ? 145.065 105.964 139.541 1.00 31.36  ? 367 LYS B CE  1 
ATOM   4304 N NZ  . LYS B 1 293 ? 143.730 105.609 140.087 1.00 34.98  ? 367 LYS B NZ  1 
ATOM   4305 N N   . ILE B 1 294 ? 141.405 108.206 135.452 1.00 25.73  ? 368 ILE B N   1 
ATOM   4306 C CA  . ILE B 1 294 ? 139.959 108.032 135.488 1.00 25.58  ? 368 ILE B CA  1 
ATOM   4307 C C   . ILE B 1 294 ? 139.650 106.671 136.093 1.00 28.87  ? 368 ILE B C   1 
ATOM   4308 O O   . ILE B 1 294 ? 140.230 105.653 135.686 1.00 35.08  ? 368 ILE B O   1 
ATOM   4309 C CB  . ILE B 1 294 ? 139.342 108.176 134.087 1.00 25.11  ? 368 ILE B CB  1 
ATOM   4310 C CG1 . ILE B 1 294 ? 139.283 109.653 133.691 1.00 22.81  ? 368 ILE B CG1 1 
ATOM   4311 C CG2 . ILE B 1 294 ? 137.953 107.562 134.043 1.00 31.41  ? 368 ILE B CG2 1 
ATOM   4312 C CD1 . ILE B 1 294 ? 138.936 109.887 132.242 1.00 28.54  ? 368 ILE B CD1 1 
ATOM   4313 N N   . MET B 1 295 ? 138.758 106.660 137.088 1.00 35.80  ? 369 MET B N   1 
ATOM   4314 C CA  . MET B 1 295 ? 138.328 105.434 137.746 1.00 33.62  ? 369 MET B CA  1 
ATOM   4315 C C   . MET B 1 295 ? 136.824 105.492 137.982 1.00 38.00  ? 369 MET B C   1 
ATOM   4316 O O   . MET B 1 295 ? 136.165 106.498 137.702 1.00 49.13  ? 369 MET B O   1 
ATOM   4317 C CB  . MET B 1 295 ? 139.052 105.209 139.081 1.00 35.78  ? 369 MET B CB  1 
ATOM   4318 C CG  . MET B 1 295 ? 140.509 105.625 139.122 1.00 41.62  ? 369 MET B CG  1 
ATOM   4319 S SD  . MET B 1 295 ? 141.148 105.600 140.808 1.00 54.20  ? 369 MET B SD  1 
ATOM   4320 C CE  . MET B 1 295 ? 141.143 103.840 141.141 1.00 41.92  ? 369 MET B CE  1 
ATOM   4321 N N   . LEU B 1 296 ? 136.283 104.394 138.502 1.00 35.96  ? 370 LEU B N   1 
ATOM   4322 C CA  . LEU B 1 296 ? 134.907 104.351 138.972 1.00 37.07  ? 370 LEU B CA  1 
ATOM   4323 C C   . LEU B 1 296 ? 134.851 104.775 140.432 1.00 44.42  ? 370 LEU B C   1 
ATOM   4324 O O   . LEU B 1 296 ? 135.708 104.395 141.235 1.00 52.97  ? 370 LEU B O   1 
ATOM   4325 C CB  . LEU B 1 296 ? 134.317 102.948 138.819 1.00 38.13  ? 370 LEU B CB  1 
ATOM   4326 C CG  . LEU B 1 296 ? 134.037 102.407 137.418 1.00 38.32  ? 370 LEU B CG  1 
ATOM   4327 C CD1 . LEU B 1 296 ? 133.619 100.953 137.499 1.00 43.83  ? 370 LEU B CD1 1 
ATOM   4328 C CD2 . LEU B 1 296 ? 132.951 103.220 136.748 1.00 42.07  ? 370 LEU B CD2 1 
ATOM   4329 N N   . SER B 1 297 ? 133.840 105.570 140.771 1.00 38.51  ? 371 SER B N   1 
ATOM   4330 C CA  . SER B 1 297 ? 133.662 105.981 142.152 1.00 39.14  ? 371 SER B CA  1 
ATOM   4331 C C   . SER B 1 297 ? 133.292 104.774 143.013 1.00 41.52  ? 371 SER B C   1 
ATOM   4332 O O   . SER B 1 297 ? 132.682 103.819 142.525 1.00 49.81  ? 371 SER B O   1 
ATOM   4333 C CB  . SER B 1 297 ? 132.582 107.054 142.257 1.00 43.84  ? 371 SER B CB  1 
ATOM   4334 O OG  . SER B 1 297 ? 131.314 106.544 141.890 1.00 45.81  ? 371 SER B OG  1 
ATOM   4335 N N   . PRO B 1 298 ? 133.677 104.778 144.292 1.00 38.52  ? 372 PRO B N   1 
ATOM   4336 C CA  . PRO B 1 298 ? 133.329 103.635 145.155 1.00 45.34  ? 372 PRO B CA  1 
ATOM   4337 C C   . PRO B 1 298 ? 131.834 103.385 145.250 1.00 51.74  ? 372 PRO B C   1 
ATOM   4338 O O   . PRO B 1 298 ? 131.405 102.226 145.298 1.00 53.18  ? 372 PRO B O   1 
ATOM   4339 C CB  . PRO B 1 298 ? 133.931 104.030 146.511 1.00 50.47  ? 372 PRO B CB  1 
ATOM   4340 C CG  . PRO B 1 298 ? 135.018 104.997 146.175 1.00 50.34  ? 372 PRO B CG  1 
ATOM   4341 C CD  . PRO B 1 298 ? 134.518 105.764 144.991 1.00 45.88  ? 372 PRO B CD  1 
ATOM   4342 N N   . GLU B 1 299 ? 131.027 104.443 145.279 1.00 55.21  ? 373 GLU B N   1 
ATOM   4343 C CA  . GLU B 1 299 ? 129.572 104.308 145.314 1.00 55.81  ? 373 GLU B CA  1 
ATOM   4344 C C   . GLU B 1 299 ? 129.001 104.513 143.911 1.00 55.49  ? 373 GLU B C   1 
ATOM   4345 O O   . GLU B 1 299 ? 128.298 105.481 143.620 1.00 58.98  ? 373 GLU B O   1 
ATOM   4346 C CB  . GLU B 1 299 ? 128.956 105.307 146.295 1.00 58.77  ? 373 GLU B CB  1 
ATOM   4347 C CG  . GLU B 1 299 ? 129.289 105.033 147.753 1.00 57.48  ? 373 GLU B CG  1 
ATOM   4348 C CD  . GLU B 1 299 ? 128.721 106.085 148.687 1.00 60.88  ? 373 GLU B CD  1 
ATOM   4349 O OE1 . GLU B 1 299 ? 128.234 107.122 148.191 1.00 62.61  ? 373 GLU B OE1 1 
ATOM   4350 O OE2 . GLU B 1 299 ? 128.764 105.874 149.918 1.00 59.88  ? 373 GLU B OE2 1 
ATOM   4351 N N   . ALA B 1 300 ? 129.322 103.568 143.031 1.00 52.03  ? 374 ALA B N   1 
ATOM   4352 C CA  . ALA B 1 300 ? 128.893 103.615 141.639 1.00 53.59  ? 374 ALA B CA  1 
ATOM   4353 C C   . ALA B 1 300 ? 128.168 102.329 141.276 1.00 56.85  ? 374 ALA B C   1 
ATOM   4354 O O   . ALA B 1 300 ? 128.660 101.232 141.559 1.00 55.35  ? 374 ALA B O   1 
ATOM   4355 C CB  . ALA B 1 300 ? 130.082 103.826 140.698 1.00 53.87  ? 374 ALA B CB  1 
ATOM   4356 N N   . ARG B 1 301 ? 127.004 102.471 140.653 1.00 68.37  ? 375 ARG B N   1 
ATOM   4357 C CA  . ARG B 1 301 ? 126.279 101.339 140.100 1.00 65.38  ? 375 ARG B CA  1 
ATOM   4358 C C   . ARG B 1 301 ? 126.722 101.093 138.665 1.00 66.43  ? 375 ARG B C   1 
ATOM   4359 O O   . ARG B 1 301 ? 127.097 102.022 137.944 1.00 69.62  ? 375 ARG B O   1 
ATOM   4360 C CB  . ARG B 1 301 ? 124.770 101.582 140.148 1.00 66.20  ? 375 ARG B CB  1 
ATOM   4361 C CG  . ARG B 1 301 ? 124.165 101.461 141.536 1.00 67.21  ? 375 ARG B CG  1 
ATOM   4362 C CD  . ARG B 1 301 ? 122.884 102.271 141.648 1.00 68.91  ? 375 ARG B CD  1 
ATOM   4363 N NE  . ARG B 1 301 ? 121.868 101.821 140.704 1.00 70.94  ? 375 ARG B NE  1 
ATOM   4364 C CZ  . ARG B 1 301 ? 120.671 102.375 140.571 1.00 70.59  ? 375 ARG B CZ  1 
ATOM   4365 N NH1 . ARG B 1 301 ? 120.303 103.410 141.309 1.00 69.20  ? 375 ARG B NH1 1 
ATOM   4366 N NH2 . ARG B 1 301 ? 119.822 101.879 139.676 1.00 69.36  ? 375 ARG B NH2 1 
ATOM   4367 N N   . ASN B 1 302 ? 126.691 99.819  138.264 1.00 56.83  ? 376 ASN B N   1 
ATOM   4368 C CA  . ASN B 1 302 ? 127.082 99.388  136.924 1.00 57.75  ? 376 ASN B CA  1 
ATOM   4369 C C   . ASN B 1 302 ? 128.558 99.659  136.653 1.00 55.49  ? 376 ASN B C   1 
ATOM   4370 O O   . ASN B 1 302 ? 129.241 100.306 137.454 1.00 57.75  ? 376 ASN B O   1 
ATOM   4371 C CB  . ASN B 1 302 ? 126.214 100.065 135.858 1.00 57.34  ? 376 ASN B CB  1 
ATOM   4372 C CG  . ASN B 1 302 ? 124.753 99.679  135.964 1.00 62.38  ? 376 ASN B CG  1 
ATOM   4373 O OD1 . ASN B 1 302 ? 123.898 100.514 136.258 1.00 63.33  ? 376 ASN B OD1 1 
ATOM   4374 N ND2 . ASN B 1 302 ? 124.458 98.406  135.723 1.00 61.58  ? 376 ASN B ND2 1 
ATOM   4375 N N   . THR B 1 303 ? 129.061 99.156  135.533 1.00 46.91  ? 377 THR B N   1 
ATOM   4376 C CA  . THR B 1 303 ? 130.442 99.350  135.123 1.00 41.81  ? 377 THR B CA  1 
ATOM   4377 C C   . THR B 1 303 ? 130.506 100.379 133.999 1.00 46.55  ? 377 THR B C   1 
ATOM   4378 O O   . THR B 1 303 ? 129.492 100.938 133.572 1.00 52.53  ? 377 THR B O   1 
ATOM   4379 C CB  . THR B 1 303 ? 131.069 98.023  134.691 1.00 45.00  ? 377 THR B CB  1 
ATOM   4380 O OG1 . THR B 1 303 ? 130.357 97.501  133.563 1.00 48.84  ? 377 THR B OG1 1 
ATOM   4381 C CG2 . THR B 1 303 ? 131.013 97.015  135.829 1.00 46.83  ? 377 THR B CG2 1 
ATOM   4382 N N   . ALA B 1 304 ? 131.721 100.629 133.518 1.00 43.40  ? 378 ALA B N   1 
ATOM   4383 C CA  . ALA B 1 304 ? 131.958 101.583 132.448 1.00 39.44  ? 378 ALA B CA  1 
ATOM   4384 C C   . ALA B 1 304 ? 132.780 100.920 131.352 1.00 47.27  ? 378 ALA B C   1 
ATOM   4385 O O   . ALA B 1 304 ? 133.469 99.922  131.579 1.00 52.83  ? 378 ALA B O   1 
ATOM   4386 C CB  . ALA B 1 304 ? 132.672 102.841 132.959 1.00 42.70  ? 378 ALA B CB  1 
ATOM   4387 N N   . TRP B 1 305 ? 132.693 101.486 130.150 1.00 42.59  ? 379 TRP B N   1 
ATOM   4388 C CA  . TRP B 1 305 ? 133.358 100.947 128.974 1.00 39.79  ? 379 TRP B CA  1 
ATOM   4389 C C   . TRP B 1 305 ? 134.265 102.011 128.375 1.00 39.23  ? 379 TRP B C   1 
ATOM   4390 O O   . TRP B 1 305 ? 133.836 103.147 128.149 1.00 45.59  ? 379 TRP B O   1 
ATOM   4391 C CB  . TRP B 1 305 ? 132.338 100.467 127.940 1.00 43.00  ? 379 TRP B CB  1 
ATOM   4392 C CG  . TRP B 1 305 ? 131.503 99.321  128.421 1.00 42.30  ? 379 TRP B CG  1 
ATOM   4393 C CD1 . TRP B 1 305 ? 130.380 99.392  129.191 1.00 45.73  ? 379 TRP B CD1 1 
ATOM   4394 C CD2 . TRP B 1 305 ? 131.731 97.929  128.172 1.00 44.82  ? 379 TRP B CD2 1 
ATOM   4395 N NE1 . TRP B 1 305 ? 129.891 98.131  129.433 1.00 48.29  ? 379 TRP B NE1 1 
ATOM   4396 C CE2 . TRP B 1 305 ? 130.703 97.215  128.818 1.00 45.22  ? 379 TRP B CE2 1 
ATOM   4397 C CE3 . TRP B 1 305 ? 132.703 97.217  127.463 1.00 44.57  ? 379 TRP B CE3 1 
ATOM   4398 C CZ2 . TRP B 1 305 ? 130.620 95.826  128.777 1.00 44.55  ? 379 TRP B CZ2 1 
ATOM   4399 C CZ3 . TRP B 1 305 ? 132.619 95.838  127.424 1.00 41.98  ? 379 TRP B CZ3 1 
ATOM   4400 C CH2 . TRP B 1 305 ? 131.585 95.158  128.077 1.00 43.76  ? 379 TRP B CH2 1 
ATOM   4401 N N   . VAL B 1 306 ? 135.509 101.632 128.110 1.00 35.37  ? 380 VAL B N   1 
ATOM   4402 C CA  . VAL B 1 306 ? 136.513 102.524 127.545 1.00 25.99  ? 380 VAL B CA  1 
ATOM   4403 C C   . VAL B 1 306 ? 136.722 102.166 126.079 1.00 36.07  ? 380 VAL B C   1 
ATOM   4404 O O   . VAL B 1 306 ? 136.818 100.983 125.721 1.00 45.83  ? 380 VAL B O   1 
ATOM   4405 C CB  . VAL B 1 306 ? 137.829 102.459 128.343 1.00 32.63  ? 380 VAL B CB  1 
ATOM   4406 C CG1 . VAL B 1 306 ? 138.418 101.059 128.323 1.00 41.09  ? 380 VAL B CG1 1 
ATOM   4407 C CG2 . VAL B 1 306 ? 138.829 103.458 127.797 1.00 30.95  ? 380 VAL B CG2 1 
ATOM   4408 N N   . SER B 1 307 ? 136.754 103.190 125.228 1.00 35.58  ? 381 SER B N   1 
ATOM   4409 C CA  . SER B 1 307 ? 136.934 103.042 123.792 1.00 32.18  ? 381 SER B CA  1 
ATOM   4410 C C   . SER B 1 307 ? 138.031 103.987 123.328 1.00 34.03  ? 381 SER B C   1 
ATOM   4411 O O   . SER B 1 307 ? 138.079 105.151 123.743 1.00 35.70  ? 381 SER B O   1 
ATOM   4412 C CB  . SER B 1 307 ? 135.633 103.331 123.032 1.00 37.30  ? 381 SER B CB  1 
ATOM   4413 O OG  . SER B 1 307 ? 135.822 103.217 121.633 1.00 44.61  ? 381 SER B OG  1 
ATOM   4414 N N   . PHE B 1 308 ? 138.908 103.480 122.465 1.00 37.67  ? 382 PHE B N   1 
ATOM   4415 C CA  . PHE B 1 308 ? 140.077 104.210 121.986 1.00 28.72  ? 382 PHE B CA  1 
ATOM   4416 C C   . PHE B 1 308 ? 139.887 104.511 120.505 1.00 33.37  ? 382 PHE B C   1 
ATOM   4417 O O   . PHE B 1 308 ? 139.968 103.606 119.669 1.00 43.61  ? 382 PHE B O   1 
ATOM   4418 C CB  . PHE B 1 308 ? 141.351 103.403 122.221 1.00 33.05  ? 382 PHE B CB  1 
ATOM   4419 C CG  . PHE B 1 308 ? 141.489 102.877 123.620 1.00 33.94  ? 382 PHE B CG  1 
ATOM   4420 C CD1 . PHE B 1 308 ? 142.096 103.637 124.604 1.00 35.39  ? 382 PHE B CD1 1 
ATOM   4421 C CD2 . PHE B 1 308 ? 141.015 101.619 123.951 1.00 34.52  ? 382 PHE B CD2 1 
ATOM   4422 C CE1 . PHE B 1 308 ? 142.222 103.154 125.890 1.00 36.13  ? 382 PHE B CE1 1 
ATOM   4423 C CE2 . PHE B 1 308 ? 141.140 101.132 125.236 1.00 36.15  ? 382 PHE B CE2 1 
ATOM   4424 C CZ  . PHE B 1 308 ? 141.745 101.900 126.206 1.00 36.45  ? 382 PHE B CZ  1 
ATOM   4425 N N   . ASP B 1 309 ? 139.627 105.780 120.188 1.00 35.70  ? 383 ASP B N   1 
ATOM   4426 C CA  . ASP B 1 309 ? 139.470 106.259 118.815 1.00 32.81  ? 383 ASP B CA  1 
ATOM   4427 C C   . ASP B 1 309 ? 138.309 105.590 118.087 1.00 34.22  ? 383 ASP B C   1 
ATOM   4428 O O   . ASP B 1 309 ? 138.265 105.595 116.853 1.00 39.77  ? 383 ASP B O   1 
ATOM   4429 C CB  . ASP B 1 309 ? 140.761 106.072 118.010 1.00 33.10  ? 383 ASP B CB  1 
ATOM   4430 C CG  . ASP B 1 309 ? 141.691 107.259 118.115 1.00 42.32  ? 383 ASP B CG  1 
ATOM   4431 O OD1 . ASP B 1 309 ? 141.195 108.402 118.152 1.00 46.51  ? 383 ASP B OD1 1 
ATOM   4432 O OD2 . ASP B 1 309 ? 142.920 107.047 118.161 1.00 44.99  ? 383 ASP B OD2 1 
ATOM   4433 N N   . GLY B 1 310 ? 137.357 105.019 118.819 1.00 39.36  ? 384 GLY B N   1 
ATOM   4434 C CA  . GLY B 1 310 ? 136.276 104.286 118.191 1.00 41.63  ? 384 GLY B CA  1 
ATOM   4435 C C   . GLY B 1 310 ? 136.704 102.900 117.754 1.00 43.30  ? 384 GLY B C   1 
ATOM   4436 O O   . GLY B 1 310 ? 136.477 102.500 116.608 1.00 49.55  ? 384 GLY B O   1 
ATOM   4437 N N   . ARG B 1 311 ? 137.323 102.161 118.666 1.00 39.61  ? 385 ARG B N   1 
ATOM   4438 C CA  . ARG B 1 311 ? 137.869 100.838 118.378 1.00 38.11  ? 385 ARG B CA  1 
ATOM   4439 C C   . ARG B 1 311 ? 137.538 99.938  119.563 1.00 46.67  ? 385 ARG B C   1 
ATOM   4440 O O   . ARG B 1 311 ? 136.631 100.233 120.349 1.00 54.07  ? 385 ARG B O   1 
ATOM   4441 C CB  . ARG B 1 311 ? 139.375 100.904 118.076 1.00 45.48  ? 385 ARG B CB  1 
ATOM   4442 C CG  . ARG B 1 311 ? 139.715 101.305 116.646 1.00 46.22  ? 385 ARG B CG  1 
ATOM   4443 C CD  . ARG B 1 311 ? 139.807 102.811 116.480 1.00 48.69  ? 385 ARG B CD  1 
ATOM   4444 N NE  . ARG B 1 311 ? 140.328 103.186 115.171 1.00 51.83  ? 385 ARG B NE  1 
ATOM   4445 C CZ  . ARG B 1 311 ? 139.572 103.448 114.113 1.00 51.60  ? 385 ARG B CZ  1 
ATOM   4446 N NH1 . ARG B 1 311 ? 138.252 103.391 114.175 1.00 47.79  ? 385 ARG B NH1 1 
ATOM   4447 N NH2 . ARG B 1 311 ? 140.156 103.776 112.964 1.00 48.90  ? 385 ARG B NH2 1 
ATOM   4448 N N   . LYS B 1 312 ? 138.256 98.818  119.667 1.00 56.80  ? 386 LYS B N   1 
ATOM   4449 C CA  . LYS B 1 312 ? 138.004 97.766  120.647 1.00 58.71  ? 386 LYS B CA  1 
ATOM   4450 C C   . LYS B 1 312 ? 137.638 98.330  122.012 1.00 56.14  ? 386 LYS B C   1 
ATOM   4451 O O   . LYS B 1 312 ? 138.393 99.110  122.602 1.00 55.78  ? 386 LYS B O   1 
ATOM   4452 C CB  . LYS B 1 312 ? 139.242 96.874  120.768 1.00 58.10  ? 386 LYS B CB  1 
ATOM   4453 C CG  . LYS B 1 312 ? 139.595 96.120  119.497 1.00 59.10  ? 386 LYS B CG  1 
ATOM   4454 C CD  . LYS B 1 312 ? 140.795 95.212  119.713 1.00 57.85  ? 386 LYS B CD  1 
ATOM   4455 C CE  . LYS B 1 312 ? 142.073 96.018  119.887 1.00 59.83  ? 386 LYS B CE  1 
ATOM   4456 N NZ  . LYS B 1 312 ? 142.444 96.748  118.643 1.00 58.00  ? 386 LYS B NZ  1 
ATOM   4457 N N   . ARG B 1 313 ? 136.472 97.930  122.509 1.00 49.85  ? 387 ARG B N   1 
ATOM   4458 C CA  . ARG B 1 313 ? 135.918 98.446  123.752 1.00 49.03  ? 387 ARG B CA  1 
ATOM   4459 C C   . ARG B 1 313 ? 136.258 97.503  124.897 1.00 51.66  ? 387 ARG B C   1 
ATOM   4460 O O   . ARG B 1 313 ? 136.036 96.292  124.798 1.00 57.20  ? 387 ARG B O   1 
ATOM   4461 C CB  . ARG B 1 313 ? 134.402 98.609  123.640 1.00 46.83  ? 387 ARG B CB  1 
ATOM   4462 C CG  . ARG B 1 313 ? 133.959 99.902  122.983 1.00 45.54  ? 387 ARG B CG  1 
ATOM   4463 C CD  . ARG B 1 313 ? 132.447 99.949  122.840 1.00 49.66  ? 387 ARG B CD  1 
ATOM   4464 N NE  . ARG B 1 313 ? 131.789 100.385 124.066 1.00 50.38  ? 387 ARG B NE  1 
ATOM   4465 C CZ  . ARG B 1 313 ? 130.866 101.334 124.122 1.00 55.73  ? 387 ARG B CZ  1 
ATOM   4466 N NH1 . ARG B 1 313 ? 130.462 101.971 123.035 1.00 53.80  ? 387 ARG B NH1 1 
ATOM   4467 N NH2 . ARG B 1 313 ? 130.332 101.652 125.298 1.00 57.54  ? 387 ARG B NH2 1 
ATOM   4468 N N   . GLN B 1 314 ? 136.793 98.060  125.977 1.00 39.30  ? 388 GLN B N   1 
ATOM   4469 C CA  . GLN B 1 314 ? 137.093 97.298  127.178 1.00 40.82  ? 388 GLN B CA  1 
ATOM   4470 C C   . GLN B 1 314 ? 136.156 97.721  128.301 1.00 49.80  ? 388 GLN B C   1 
ATOM   4471 O O   . GLN B 1 314 ? 135.519 98.773  128.241 1.00 50.65  ? 388 GLN B O   1 
ATOM   4472 C CB  . GLN B 1 314 ? 138.552 97.492  127.604 1.00 45.11  ? 388 GLN B CB  1 
ATOM   4473 C CG  . GLN B 1 314 ? 139.558 97.225  126.499 1.00 46.87  ? 388 GLN B CG  1 
ATOM   4474 C CD  . GLN B 1 314 ? 140.990 97.246  126.994 1.00 52.00  ? 388 GLN B CD  1 
ATOM   4475 O OE1 . GLN B 1 314 ? 141.932 97.259  126.203 1.00 53.82  ? 388 GLN B OE1 1 
ATOM   4476 N NE2 . GLN B 1 314 ? 141.161 97.245  128.311 1.00 52.75  ? 388 GLN B NE2 1 
ATOM   4477 N N   . GLU B 1 315 ? 136.077 96.886  129.331 1.00 51.03  ? 389 GLU B N   1 
ATOM   4478 C CA  . GLU B 1 315 ? 135.227 97.139  130.487 1.00 44.35  ? 389 GLU B CA  1 
ATOM   4479 C C   . GLU B 1 315 ? 136.101 97.362  131.712 1.00 48.68  ? 389 GLU B C   1 
ATOM   4480 O O   . GLU B 1 315 ? 137.063 96.620  131.934 1.00 53.05  ? 389 GLU B O   1 
ATOM   4481 C CB  . GLU B 1 315 ? 134.268 95.972  130.724 1.00 47.22  ? 389 GLU B CB  1 
ATOM   4482 C CG  . GLU B 1 315 ? 133.186 96.257  131.748 1.00 50.48  ? 389 GLU B CG  1 
ATOM   4483 C CD  . GLU B 1 315 ? 132.411 95.015  132.136 1.00 51.92  ? 389 GLU B CD  1 
ATOM   4484 O OE1 . GLU B 1 315 ? 132.842 93.903  131.766 1.00 53.67  ? 389 GLU B OE1 1 
ATOM   4485 O OE2 . GLU B 1 315 ? 131.368 95.150  132.810 1.00 54.52  ? 389 GLU B OE2 1 
ATOM   4486 N N   . ILE B 1 316 ? 135.770 98.381  132.503 1.00 49.18  ? 390 ILE B N   1 
ATOM   4487 C CA  . ILE B 1 316 ? 136.528 98.722  133.701 1.00 48.36  ? 390 ILE B CA  1 
ATOM   4488 C C   . ILE B 1 316 ? 135.644 98.508  134.922 1.00 48.49  ? 390 ILE B C   1 
ATOM   4489 O O   . ILE B 1 316 ? 134.521 99.025  134.985 1.00 50.01  ? 390 ILE B O   1 
ATOM   4490 C CB  . ILE B 1 316 ? 137.063 100.165 133.646 1.00 42.27  ? 390 ILE B CB  1 
ATOM   4491 C CG1 . ILE B 1 316 ? 135.986 101.131 133.151 1.00 45.33  ? 390 ILE B CG1 1 
ATOM   4492 C CG2 . ILE B 1 316 ? 138.292 100.242 132.755 1.00 44.17  ? 390 ILE B CG2 1 
ATOM   4493 C CD1 . ILE B 1 316 ? 136.304 102.583 133.429 1.00 49.86  ? 390 ILE B CD1 1 
ATOM   4494 N N   . ARG B 1 317 ? 136.147 97.737  135.881 1.00 50.49  ? 391 ARG B N   1 
ATOM   4495 C CA  . ARG B 1 317 ? 135.470 97.499  137.145 1.00 46.80  ? 391 ARG B CA  1 
ATOM   4496 C C   . ARG B 1 317 ? 135.944 98.532  138.167 1.00 52.44  ? 391 ARG B C   1 
ATOM   4497 O O   . ARG B 1 317 ? 136.598 99.521  137.825 1.00 57.28  ? 391 ARG B O   1 
ATOM   4498 C CB  . ARG B 1 317 ? 135.720 96.070  137.626 1.00 50.17  ? 391 ARG B CB  1 
ATOM   4499 C CG  . ARG B 1 317 ? 134.860 95.006  136.954 1.00 51.67  ? 391 ARG B CG  1 
ATOM   4500 C CD  . ARG B 1 317 ? 135.369 94.663  135.564 1.00 48.14  ? 391 ARG B CD  1 
ATOM   4501 N NE  . ARG B 1 317 ? 134.591 93.598  134.943 1.00 53.45  ? 391 ARG B NE  1 
ATOM   4502 C CZ  . ARG B 1 317 ? 134.846 92.305  135.081 1.00 54.78  ? 391 ARG B CZ  1 
ATOM   4503 N NH1 . ARG B 1 317 ? 135.858 91.875  135.817 1.00 53.11  ? 391 ARG B NH1 1 
ATOM   4504 N NH2 . ARG B 1 317 ? 134.067 91.420  134.465 1.00 54.98  ? 391 ARG B NH2 1 
ATOM   4505 N N   . HIS B 1 318 ? 135.615 98.313  139.442 1.00 49.77  ? 392 HIS B N   1 
ATOM   4506 C CA  . HIS B 1 318 ? 136.019 99.256  140.480 1.00 54.45  ? 392 HIS B CA  1 
ATOM   4507 C C   . HIS B 1 318 ? 137.527 99.254  140.696 1.00 54.90  ? 392 HIS B C   1 
ATOM   4508 O O   . HIS B 1 318 ? 138.092 100.271 141.113 1.00 57.38  ? 392 HIS B O   1 
ATOM   4509 C CB  . HIS B 1 318 ? 135.296 98.941  141.788 1.00 54.16  ? 392 HIS B CB  1 
ATOM   4510 C CG  . HIS B 1 318 ? 133.832 99.249  141.758 1.00 55.05  ? 392 HIS B CG  1 
ATOM   4511 N ND1 . HIS B 1 318 ? 132.890 98.348  141.312 1.00 61.25  ? 392 HIS B ND1 1 
ATOM   4512 C CD2 . HIS B 1 318 ? 133.148 100.361 142.117 1.00 52.69  ? 392 HIS B CD2 1 
ATOM   4513 C CE1 . HIS B 1 318 ? 131.689 98.891  141.397 1.00 59.98  ? 392 HIS B CE1 1 
ATOM   4514 N NE2 . HIS B 1 318 ? 131.817 100.112 141.883 1.00 57.83  ? 392 HIS B NE2 1 
ATOM   4515 N N   . GLY B 1 319 ? 138.192 98.136  140.422 1.00 48.61  ? 393 GLY B N   1 
ATOM   4516 C CA  . GLY B 1 319 ? 139.622 98.029  140.601 1.00 53.03  ? 393 GLY B CA  1 
ATOM   4517 C C   . GLY B 1 319 ? 140.470 98.465  139.429 1.00 59.04  ? 393 GLY B C   1 
ATOM   4518 O O   . GLY B 1 319 ? 141.698 98.355  139.494 1.00 59.54  ? 393 GLY B O   1 
ATOM   4519 N N   . ASP B 1 320 ? 139.861 98.958  138.355 1.00 56.02  ? 394 ASP B N   1 
ATOM   4520 C CA  . ASP B 1 320 ? 140.586 99.337  137.153 1.00 48.66  ? 394 ASP B CA  1 
ATOM   4521 C C   . ASP B 1 320 ? 140.812 100.843 137.119 1.00 47.17  ? 394 ASP B C   1 
ATOM   4522 O O   . ASP B 1 320 ? 140.027 101.620 137.668 1.00 52.80  ? 394 ASP B O   1 
ATOM   4523 C CB  . ASP B 1 320 ? 139.826 98.900  135.899 1.00 51.64  ? 394 ASP B CB  1 
ATOM   4524 C CG  . ASP B 1 320 ? 139.511 97.419  135.898 1.00 57.43  ? 394 ASP B CG  1 
ATOM   4525 O OD1 . ASP B 1 320 ? 140.453 96.607  135.881 1.00 59.44  ? 394 ASP B OD1 1 
ATOM   4526 O OD2 . ASP B 1 320 ? 138.318 97.063  135.903 1.00 59.00  ? 394 ASP B OD2 1 
ATOM   4527 N N   . SER B 1 321 ? 141.899 101.250 136.465 1.00 39.95  ? 395 SER B N   1 
ATOM   4528 C CA  . SER B 1 321 ? 142.229 102.661 136.333 1.00 39.29  ? 395 SER B CA  1 
ATOM   4529 C C   . SER B 1 321 ? 142.719 102.941 134.921 1.00 41.51  ? 395 SER B C   1 
ATOM   4530 O O   . SER B 1 321 ? 143.297 102.070 134.265 1.00 47.68  ? 395 SER B O   1 
ATOM   4531 C CB  . SER B 1 321 ? 143.295 103.089 137.350 1.00 42.96  ? 395 SER B CB  1 
ATOM   4532 O OG  . SER B 1 321 ? 144.533 102.453 137.087 1.00 48.56  ? 395 SER B OG  1 
ATOM   4533 N N   . ILE B 1 322 ? 142.483 104.167 134.456 1.00 33.64  ? 396 ILE B N   1 
ATOM   4534 C CA  . ILE B 1 322 ? 142.941 104.614 133.144 1.00 28.83  ? 396 ILE B CA  1 
ATOM   4535 C C   . ILE B 1 322 ? 143.830 105.833 133.347 1.00 32.16  ? 396 ILE B C   1 
ATOM   4536 O O   . ILE B 1 322 ? 143.397 106.825 133.941 1.00 36.32  ? 396 ILE B O   1 
ATOM   4537 C CB  . ILE B 1 322 ? 141.764 104.942 132.213 1.00 24.35  ? 396 ILE B CB  1 
ATOM   4538 C CG1 . ILE B 1 322 ? 140.691 103.856 132.305 1.00 28.44  ? 396 ILE B CG1 1 
ATOM   4539 C CG2 . ILE B 1 322 ? 142.240 105.102 130.786 1.00 28.72  ? 396 ILE B CG2 1 
ATOM   4540 C CD1 . ILE B 1 322 ? 139.508 104.087 131.396 1.00 34.76  ? 396 ILE B CD1 1 
ATOM   4541 N N   . SER B 1 323 ? 145.061 105.769 132.846 1.00 23.76  ? 397 SER B N   1 
ATOM   4542 C CA  . SER B 1 323 ? 146.025 106.855 132.986 1.00 18.22  ? 397 SER B CA  1 
ATOM   4543 C C   . SER B 1 323 ? 146.320 107.436 131.611 1.00 25.51  ? 397 SER B C   1 
ATOM   4544 O O   . SER B 1 323 ? 146.741 106.711 130.706 1.00 40.02  ? 397 SER B O   1 
ATOM   4545 C CB  . SER B 1 323 ? 147.310 106.363 133.651 1.00 32.83  ? 397 SER B CB  1 
ATOM   4546 O OG  . SER B 1 323 ? 147.063 105.926 134.976 1.00 42.29  ? 397 SER B OG  1 
ATOM   4547 N N   . ILE B 1 324 ? 146.111 108.740 131.461 1.00 22.95  ? 398 ILE B N   1 
ATOM   4548 C CA  . ILE B 1 324 ? 146.230 109.427 130.181 1.00 16.38  ? 398 ILE B CA  1 
ATOM   4549 C C   . ILE B 1 324 ? 147.271 110.529 130.309 1.00 17.07  ? 398 ILE B C   1 
ATOM   4550 O O   . ILE B 1 324 ? 147.206 111.348 131.233 1.00 34.11  ? 398 ILE B O   1 
ATOM   4551 C CB  . ILE B 1 324 ? 144.879 110.004 129.722 1.00 19.24  ? 398 ILE B CB  1 
ATOM   4552 C CG1 . ILE B 1 324 ? 143.805 108.915 129.730 1.00 26.88  ? 398 ILE B CG1 1 
ATOM   4553 C CG2 . ILE B 1 324 ? 145.005 110.624 128.341 1.00 29.48  ? 398 ILE B CG2 1 
ATOM   4554 C CD1 . ILE B 1 324 ? 142.411 109.436 129.963 1.00 29.61  ? 398 ILE B CD1 1 
ATOM   4555 N N   . THR B 1 325 ? 148.227 110.543 129.382 1.00 26.46  ? 399 THR B N   1 
ATOM   4556 C CA  . THR B 1 325 ? 149.241 111.586 129.299 1.00 25.16  ? 399 THR B CA  1 
ATOM   4557 C C   . THR B 1 325 ? 149.415 111.971 127.836 1.00 28.39  ? 399 THR B C   1 
ATOM   4558 O O   . THR B 1 325 ? 148.831 111.357 126.940 1.00 35.24  ? 399 THR B O   1 
ATOM   4559 C CB  . THR B 1 325 ? 150.575 111.128 129.904 1.00 28.70  ? 399 THR B CB  1 
ATOM   4560 O OG1 . THR B 1 325 ? 150.919 109.837 129.386 1.00 35.61  ? 399 THR B OG1 1 
ATOM   4561 C CG2 . THR B 1 325 ? 150.485 111.058 131.419 1.00 31.36  ? 399 THR B CG2 1 
ATOM   4562 N N   . THR B 1 326 ? 150.230 112.992 127.590 1.00 31.74  ? 400 THR B N   1 
ATOM   4563 C CA  . THR B 1 326 ? 150.541 113.416 126.230 1.00 20.32  ? 400 THR B CA  1 
ATOM   4564 C C   . THR B 1 326 ? 151.713 112.594 125.711 1.00 27.17  ? 400 THR B C   1 
ATOM   4565 O O   . THR B 1 326 ? 152.788 112.580 126.320 1.00 38.05  ? 400 THR B O   1 
ATOM   4566 C CB  . THR B 1 326 ? 150.867 114.907 126.178 1.00 27.49  ? 400 THR B CB  1 
ATOM   4567 O OG1 . THR B 1 326 ? 149.926 115.632 126.978 1.00 40.27  ? 400 THR B OG1 1 
ATOM   4568 C CG2 . THR B 1 326 ? 150.801 115.414 124.747 1.00 26.40  ? 400 THR B CG2 1 
ATOM   4569 N N   . SER B 1 327 ? 151.503 111.912 124.589 1.00 28.54  ? 401 SER B N   1 
ATOM   4570 C CA  . SER B 1 327 ? 152.528 111.041 124.035 1.00 26.18  ? 401 SER B CA  1 
ATOM   4571 C C   . SER B 1 327 ? 153.684 111.853 123.461 1.00 34.29  ? 401 SER B C   1 
ATOM   4572 O O   . SER B 1 327 ? 153.520 112.999 123.033 1.00 38.01  ? 401 SER B O   1 
ATOM   4573 C CB  . SER B 1 327 ? 151.934 110.142 122.952 1.00 30.81  ? 401 SER B CB  1 
ATOM   4574 O OG  . SER B 1 327 ? 152.953 109.485 122.220 1.00 35.82  ? 401 SER B OG  1 
ATOM   4575 N N   . THR B 1 328 ? 154.864 111.241 123.457 1.00 36.76  ? 402 THR B N   1 
ATOM   4576 C CA  . THR B 1 328 ? 156.063 111.849 122.899 1.00 36.82  ? 402 THR B CA  1 
ATOM   4577 C C   . THR B 1 328 ? 156.246 111.540 121.419 1.00 42.22  ? 402 THR B C   1 
ATOM   4578 O O   . THR B 1 328 ? 157.260 111.939 120.838 1.00 38.62  ? 402 THR B O   1 
ATOM   4579 C CB  . THR B 1 328 ? 157.302 111.387 123.673 1.00 38.19  ? 402 THR B CB  1 
ATOM   4580 O OG1 . THR B 1 328 ? 157.437 109.966 123.561 1.00 35.49  ? 402 THR B OG1 1 
ATOM   4581 C CG2 . THR B 1 328 ? 157.182 111.765 125.141 1.00 39.11  ? 402 THR B CG2 1 
ATOM   4582 N N   . TYR B 1 329 ? 155.294 110.840 120.799 1.00 42.24  ? 403 TYR B N   1 
ATOM   4583 C CA  . TYR B 1 329 ? 155.369 110.451 119.392 1.00 34.34  ? 403 TYR B CA  1 
ATOM   4584 C C   . TYR B 1 329 ? 154.167 111.032 118.659 1.00 34.17  ? 403 TYR B C   1 
ATOM   4585 O O   . TYR B 1 329 ? 153.121 110.374 118.544 1.00 38.01  ? 403 TYR B O   1 
ATOM   4586 C CB  . TYR B 1 329 ? 155.415 108.933 119.246 1.00 33.03  ? 403 TYR B CB  1 
ATOM   4587 C CG  . TYR B 1 329 ? 156.564 108.274 119.973 1.00 39.12  ? 403 TYR B CG  1 
ATOM   4588 C CD1 . TYR B 1 329 ? 157.877 108.493 119.580 1.00 40.68  ? 403 TYR B CD1 1 
ATOM   4589 C CD2 . TYR B 1 329 ? 156.335 107.429 121.050 1.00 35.84  ? 403 TYR B CD2 1 
ATOM   4590 C CE1 . TYR B 1 329 ? 158.930 107.890 120.240 1.00 39.03  ? 403 TYR B CE1 1 
ATOM   4591 C CE2 . TYR B 1 329 ? 157.381 106.822 121.717 1.00 33.84  ? 403 TYR B CE2 1 
ATOM   4592 C CZ  . TYR B 1 329 ? 158.676 107.057 121.308 1.00 38.47  ? 403 TYR B CZ  1 
ATOM   4593 O OH  . TYR B 1 329 ? 159.721 106.455 121.969 1.00 42.60  ? 403 TYR B OH  1 
ATOM   4594 N N   . PRO B 1 330 ? 154.269 112.255 118.149 1.00 29.99  ? 404 PRO B N   1 
ATOM   4595 C CA  . PRO B 1 330 ? 153.156 112.838 117.394 1.00 31.46  ? 404 PRO B CA  1 
ATOM   4596 C C   . PRO B 1 330 ? 153.022 112.194 116.022 1.00 38.10  ? 404 PRO B C   1 
ATOM   4597 O O   . PRO B 1 330 ? 153.888 111.452 115.556 1.00 44.72  ? 404 PRO B O   1 
ATOM   4598 C CB  . PRO B 1 330 ? 153.542 114.315 117.285 1.00 33.45  ? 404 PRO B CB  1 
ATOM   4599 C CG  . PRO B 1 330 ? 155.028 114.305 117.351 1.00 34.47  ? 404 PRO B CG  1 
ATOM   4600 C CD  . PRO B 1 330 ? 155.378 113.209 118.318 1.00 33.31  ? 404 PRO B CD  1 
ATOM   4601 N N   . LEU B 1 331 ? 151.898 112.492 115.371 1.00 30.65  ? 405 LEU B N   1 
ATOM   4602 C CA  . LEU B 1 331 ? 151.625 111.992 114.027 1.00 16.64  ? 405 LEU B CA  1 
ATOM   4603 C C   . LEU B 1 331 ? 151.761 113.137 113.035 1.00 26.40  ? 405 LEU B C   1 
ATOM   4604 O O   . LEU B 1 331 ? 150.864 113.990 112.944 1.00 35.64  ? 405 LEU B O   1 
ATOM   4605 C CB  . LEU B 1 331 ? 150.224 111.374 113.953 1.00 24.99  ? 405 LEU B CB  1 
ATOM   4606 C CG  . LEU B 1 331 ? 149.811 110.607 112.692 1.00 18.27  ? 405 LEU B CG  1 
ATOM   4607 C CD1 . LEU B 1 331 ? 148.822 109.515 113.049 1.00 25.57  ? 405 LEU B CD1 1 
ATOM   4608 C CD2 . LEU B 1 331 ? 149.204 111.525 111.643 1.00 29.76  ? 405 LEU B CD2 1 
ATOM   4609 N N   . PRO B 1 332 ? 152.857 113.214 112.277 1.00 24.61  ? 406 PRO B N   1 
ATOM   4610 C CA  . PRO B 1 332 ? 153.006 114.285 111.281 1.00 19.88  ? 406 PRO B CA  1 
ATOM   4611 C C   . PRO B 1 332 ? 152.146 114.005 110.058 1.00 31.54  ? 406 PRO B C   1 
ATOM   4612 O O   . PRO B 1 332 ? 152.304 112.978 109.394 1.00 42.74  ? 406 PRO B O   1 
ATOM   4613 C CB  . PRO B 1 332 ? 154.501 114.244 110.941 1.00 25.27  ? 406 PRO B CB  1 
ATOM   4614 C CG  . PRO B 1 332 ? 154.909 112.844 111.242 1.00 23.88  ? 406 PRO B CG  1 
ATOM   4615 C CD  . PRO B 1 332 ? 154.088 112.418 112.422 1.00 29.48  ? 406 PRO B CD  1 
ATOM   4616 N N   . SER B 1 333 ? 151.230 114.921 109.762 1.00 22.79  ? 407 SER B N   1 
ATOM   4617 C CA  . SER B 1 333 ? 150.384 114.833 108.579 1.00 26.73  ? 407 SER B CA  1 
ATOM   4618 C C   . SER B 1 333 ? 150.720 115.996 107.656 1.00 27.35  ? 407 SER B C   1 
ATOM   4619 O O   . SER B 1 333 ? 150.603 117.161 108.051 1.00 33.33  ? 407 SER B O   1 
ATOM   4620 C CB  . SER B 1 333 ? 148.903 114.843 108.953 1.00 29.14  ? 407 SER B CB  1 
ATOM   4621 O OG  . SER B 1 333 ? 148.521 116.088 109.506 1.00 33.67  ? 407 SER B OG  1 
ATOM   4622 N N   . ILE B 1 334 ? 151.136 115.674 106.431 1.00 27.57  ? 408 ILE B N   1 
ATOM   4623 C CA  . ILE B 1 334 ? 151.532 116.697 105.475 1.00 20.84  ? 408 ILE B CA  1 
ATOM   4624 C C   . ILE B 1 334 ? 150.319 117.522 105.071 1.00 31.29  ? 408 ILE B C   1 
ATOM   4625 O O   . ILE B 1 334 ? 149.230 116.986 104.826 1.00 41.91  ? 408 ILE B O   1 
ATOM   4626 C CB  . ILE B 1 334 ? 152.202 116.051 104.252 1.00 25.20  ? 408 ILE B CB  1 
ATOM   4627 C CG1 . ILE B 1 334 ? 153.112 114.905 104.696 1.00 22.16  ? 408 ILE B CG1 1 
ATOM   4628 C CG2 . ILE B 1 334 ? 152.982 117.085 103.463 1.00 32.68  ? 408 ILE B CG2 1 
ATOM   4629 C CD1 . ILE B 1 334 ? 153.794 114.191 103.560 1.00 25.05  ? 408 ILE B CD1 1 
ATOM   4630 N N   . CYS B 1 335 ? 150.504 118.836 104.998 1.00 30.94  ? 409 CYS B N   1 
ATOM   4631 C CA  . CYS B 1 335 ? 149.437 119.765 104.666 1.00 28.65  ? 409 CYS B CA  1 
ATOM   4632 C C   . CYS B 1 335 ? 149.576 120.233 103.224 1.00 36.78  ? 409 CYS B C   1 
ATOM   4633 O O   . CYS B 1 335 ? 150.649 120.152 102.620 1.00 40.89  ? 409 CYS B O   1 
ATOM   4634 C CB  . CYS B 1 335 ? 149.446 120.970 105.613 1.00 36.84  ? 409 CYS B CB  1 
ATOM   4635 S SG  . CYS B 1 335 ? 150.921 122.004 105.491 1.00 57.63  ? 409 CYS B SG  1 
ATOM   4636 N N   . VAL B 1 336 ? 148.468 120.726 102.676 1.00 40.18  ? 410 VAL B N   1 
ATOM   4637 C CA  . VAL B 1 336 ? 148.456 121.171 101.285 1.00 32.60  ? 410 VAL B CA  1 
ATOM   4638 C C   . VAL B 1 336 ? 149.214 122.483 101.132 1.00 34.83  ? 410 VAL B C   1 
ATOM   4639 O O   . VAL B 1 336 ? 150.207 122.564 100.399 1.00 39.21  ? 410 VAL B O   1 
ATOM   4640 C CB  . VAL B 1 336 ? 147.011 121.294 100.770 1.00 30.51  ? 410 VAL B CB  1 
ATOM   4641 C CG1 . VAL B 1 336 ? 146.998 121.870 99.365  1.00 38.13  ? 410 VAL B CG1 1 
ATOM   4642 C CG2 . VAL B 1 336 ? 146.327 119.941 100.795 1.00 35.23  ? 410 VAL B CG2 1 
ATOM   4643 N N   . ARG B 1 337 ? 148.760 123.530 101.818 1.00 38.52  ? 411 ARG B N   1 
ATOM   4644 C CA  . ARG B 1 337 ? 149.371 124.849 101.704 1.00 42.83  ? 411 ARG B CA  1 
ATOM   4645 C C   . ARG B 1 337 ? 149.968 125.359 103.009 1.00 45.77  ? 411 ARG B C   1 
ATOM   4646 O O   . ARG B 1 337 ? 151.136 125.761 103.026 1.00 50.94  ? 411 ARG B O   1 
ATOM   4647 C CB  . ARG B 1 337 ? 148.344 125.844 101.133 1.00 42.99  ? 411 ARG B CB  1 
ATOM   4648 C CG  . ARG B 1 337 ? 147.117 126.088 101.986 1.00 45.11  ? 411 ARG B CG  1 
ATOM   4649 C CD  . ARG B 1 337 ? 146.179 127.086 101.329 1.00 46.71  ? 411 ARG B CD  1 
ATOM   4650 N NE  . ARG B 1 337 ? 145.631 126.576 100.078 1.00 50.01  ? 411 ARG B NE  1 
ATOM   4651 C CZ  . ARG B 1 337 ? 144.529 125.845 99.987  1.00 53.67  ? 411 ARG B CZ  1 
ATOM   4652 N NH1 . ARG B 1 337 ? 143.829 125.514 101.059 1.00 52.73  ? 411 ARG B NH1 1 
ATOM   4653 N NH2 . ARG B 1 337 ? 144.118 125.437 98.790  1.00 52.53  ? 411 ARG B NH2 1 
ATOM   4654 N N   . ASP B 1 338 ? 149.218 125.351 104.105 1.00 42.16  ? 412 ASP B N   1 
ATOM   4655 C CA  . ASP B 1 338 ? 149.738 125.737 105.411 1.00 40.00  ? 412 ASP B CA  1 
ATOM   4656 C C   . ASP B 1 338 ? 148.743 125.279 106.477 1.00 44.05  ? 412 ASP B C   1 
ATOM   4657 O O   . ASP B 1 338 ? 147.573 125.037 106.166 1.00 49.17  ? 412 ASP B O   1 
ATOM   4658 C CB  . ASP B 1 338 ? 149.979 127.256 105.499 1.00 42.15  ? 412 ASP B CB  1 
ATOM   4659 C CG  . ASP B 1 338 ? 148.738 128.065 105.213 1.00 48.89  ? 412 ASP B CG  1 
ATOM   4660 O OD1 . ASP B 1 338 ? 147.864 128.135 106.100 1.00 52.37  ? 412 ASP B OD1 1 
ATOM   4661 O OD2 . ASP B 1 338 ? 148.633 128.630 104.104 1.00 52.87  ? 412 ASP B OD2 1 
ATOM   4662 N N   . PRO B 1 339 ? 149.191 125.147 107.731 1.00 37.44  ? 413 PRO B N   1 
ATOM   4663 C CA  . PRO B 1 339 ? 148.300 124.584 108.765 1.00 36.87  ? 413 PRO B CA  1 
ATOM   4664 C C   . PRO B 1 339 ? 147.012 125.362 108.988 1.00 38.32  ? 413 PRO B C   1 
ATOM   4665 O O   . PRO B 1 339 ? 145.924 124.772 108.943 1.00 45.04  ? 413 PRO B O   1 
ATOM   4666 C CB  . PRO B 1 339 ? 149.186 124.590 110.017 1.00 37.17  ? 413 PRO B CB  1 
ATOM   4667 C CG  . PRO B 1 339 ? 150.573 124.532 109.503 1.00 38.83  ? 413 PRO B CG  1 
ATOM   4668 C CD  . PRO B 1 339 ? 150.579 125.278 108.207 1.00 39.51  ? 413 PRO B CD  1 
ATOM   4669 N N   . VAL B 1 340 ? 147.102 126.669 109.247 1.00 32.59  ? 414 VAL B N   1 
ATOM   4670 C CA  . VAL B 1 340 ? 145.929 127.423 109.685 1.00 35.61  ? 414 VAL B CA  1 
ATOM   4671 C C   . VAL B 1 340 ? 144.875 127.497 108.583 1.00 38.86  ? 414 VAL B C   1 
ATOM   4672 O O   . VAL B 1 340 ? 143.674 127.336 108.844 1.00 43.88  ? 414 VAL B O   1 
ATOM   4673 C CB  . VAL B 1 340 ? 146.347 128.820 110.186 1.00 40.45  ? 414 VAL B CB  1 
ATOM   4674 C CG1 . VAL B 1 340 ? 147.267 128.691 111.387 1.00 37.34  ? 414 VAL B CG1 1 
ATOM   4675 C CG2 . VAL B 1 340 ? 147.042 129.614 109.090 1.00 39.45  ? 414 VAL B CG2 1 
ATOM   4676 N N   . SER B 1 341 ? 145.295 127.737 107.339 1.00 33.56  ? 415 SER B N   1 
ATOM   4677 C CA  . SER B 1 341 ? 144.325 127.848 106.255 1.00 33.52  ? 415 SER B CA  1 
ATOM   4678 C C   . SER B 1 341 ? 143.664 126.507 105.970 1.00 37.75  ? 415 SER B C   1 
ATOM   4679 O O   . SER B 1 341 ? 142.465 126.454 105.686 1.00 44.94  ? 415 SER B O   1 
ATOM   4680 C CB  . SER B 1 341 ? 144.991 128.395 104.996 1.00 36.67  ? 415 SER B CB  1 
ATOM   4681 O OG  . SER B 1 341 ? 145.936 127.471 104.497 1.00 42.86  ? 415 SER B OG  1 
ATOM   4682 N N   . ASP B 1 342 ? 144.427 125.414 106.040 1.00 31.10  ? 416 ASP B N   1 
ATOM   4683 C CA  . ASP B 1 342 ? 143.830 124.092 105.877 1.00 35.46  ? 416 ASP B CA  1 
ATOM   4684 C C   . ASP B 1 342 ? 142.840 123.792 106.996 1.00 39.23  ? 416 ASP B C   1 
ATOM   4685 O O   . ASP B 1 342 ? 141.775 123.212 106.754 1.00 41.46  ? 416 ASP B O   1 
ATOM   4686 C CB  . ASP B 1 342 ? 144.919 123.021 105.820 1.00 37.15  ? 416 ASP B CB  1 
ATOM   4687 C CG  . ASP B 1 342 ? 145.748 123.101 104.555 1.00 45.95  ? 416 ASP B CG  1 
ATOM   4688 O OD1 . ASP B 1 342 ? 145.211 123.547 103.519 1.00 47.98  ? 416 ASP B OD1 1 
ATOM   4689 O OD2 . ASP B 1 342 ? 146.933 122.712 104.594 1.00 48.03  ? 416 ASP B OD2 1 
ATOM   4690 N N   . TRP B 1 343 ? 143.173 124.181 108.229 1.00 35.87  ? 417 TRP B N   1 
ATOM   4691 C CA  . TRP B 1 343 ? 142.256 123.968 109.345 1.00 28.49  ? 417 TRP B CA  1 
ATOM   4692 C C   . TRP B 1 343 ? 140.957 124.740 109.148 1.00 34.11  ? 417 TRP B C   1 
ATOM   4693 O O   . TRP B 1 343 ? 139.865 124.202 109.368 1.00 37.55  ? 417 TRP B O   1 
ATOM   4694 C CB  . TRP B 1 343 ? 142.927 124.371 110.658 1.00 32.14  ? 417 TRP B CB  1 
ATOM   4695 C CG  . TRP B 1 343 ? 142.155 123.971 111.877 1.00 32.55  ? 417 TRP B CG  1 
ATOM   4696 C CD1 . TRP B 1 343 ? 141.870 122.703 112.286 1.00 28.41  ? 417 TRP B CD1 1 
ATOM   4697 C CD2 . TRP B 1 343 ? 141.571 124.847 112.848 1.00 36.61  ? 417 TRP B CD2 1 
ATOM   4698 N NE1 . TRP B 1 343 ? 141.143 122.733 113.450 1.00 31.38  ? 417 TRP B NE1 1 
ATOM   4699 C CE2 . TRP B 1 343 ? 140.947 124.038 113.816 1.00 32.66  ? 417 TRP B CE2 1 
ATOM   4700 C CE3 . TRP B 1 343 ? 141.516 126.236 112.992 1.00 35.85  ? 417 TRP B CE3 1 
ATOM   4701 C CZ2 . TRP B 1 343 ? 140.275 124.572 114.913 1.00 32.35  ? 417 TRP B CZ2 1 
ATOM   4702 C CZ3 . TRP B 1 343 ? 140.850 126.763 114.081 1.00 33.17  ? 417 TRP B CZ3 1 
ATOM   4703 C CH2 . TRP B 1 343 ? 140.238 125.933 115.027 1.00 32.54  ? 417 TRP B CH2 1 
ATOM   4704 N N   . PHE B 1 344 ? 141.052 126.002 108.722 1.00 37.49  ? 418 PHE B N   1 
ATOM   4705 C CA  . PHE B 1 344 ? 139.838 126.788 108.517 1.00 29.69  ? 418 PHE B CA  1 
ATOM   4706 C C   . PHE B 1 344 ? 139.054 126.311 107.299 1.00 28.36  ? 418 PHE B C   1 
ATOM   4707 O O   . PHE B 1 344 ? 137.822 126.377 107.295 1.00 37.78  ? 418 PHE B O   1 
ATOM   4708 C CB  . PHE B 1 344 ? 140.184 128.271 108.400 1.00 27.98  ? 418 PHE B CB  1 
ATOM   4709 C CG  . PHE B 1 344 ? 140.330 128.957 109.727 1.00 34.27  ? 418 PHE B CG  1 
ATOM   4710 C CD1 . PHE B 1 344 ? 139.230 129.506 110.362 1.00 36.23  ? 418 PHE B CD1 1 
ATOM   4711 C CD2 . PHE B 1 344 ? 141.564 129.040 110.347 1.00 34.80  ? 418 PHE B CD2 1 
ATOM   4712 C CE1 . PHE B 1 344 ? 139.361 130.132 111.586 1.00 38.39  ? 418 PHE B CE1 1 
ATOM   4713 C CE2 . PHE B 1 344 ? 141.701 129.664 111.569 1.00 33.28  ? 418 PHE B CE2 1 
ATOM   4714 C CZ  . PHE B 1 344 ? 140.598 130.211 112.190 1.00 36.81  ? 418 PHE B CZ  1 
ATOM   4715 N N   . GLU B 1 345 ? 139.744 125.819 106.270 1.00 22.75  ? 419 GLU B N   1 
ATOM   4716 C CA  . GLU B 1 345 ? 139.083 125.184 105.133 1.00 23.32  ? 419 GLU B CA  1 
ATOM   4717 C C   . GLU B 1 345 ? 138.297 123.950 105.563 1.00 30.02  ? 419 GLU B C   1 
ATOM   4718 O O   . GLU B 1 345 ? 137.152 123.743 105.130 1.00 35.76  ? 419 GLU B O   1 
ATOM   4719 C CB  . GLU B 1 345 ? 140.153 124.844 104.091 1.00 28.74  ? 419 GLU B CB  1 
ATOM   4720 C CG  . GLU B 1 345 ? 139.692 124.370 102.731 1.00 33.93  ? 419 GLU B CG  1 
ATOM   4721 C CD  . GLU B 1 345 ? 139.401 122.885 102.716 1.00 40.20  ? 419 GLU B CD  1 
ATOM   4722 O OE1 . GLU B 1 345 ? 140.026 122.151 103.509 1.00 41.72  ? 419 GLU B OE1 1 
ATOM   4723 O OE2 . GLU B 1 345 ? 138.589 122.441 101.884 1.00 39.41  ? 419 GLU B OE2 1 
ATOM   4724 N N   . SER B 1 346 ? 138.896 123.120 106.419 1.00 32.17  ? 420 SER B N   1 
ATOM   4725 C CA  . SER B 1 346 ? 138.192 121.958 106.946 1.00 23.97  ? 420 SER B CA  1 
ATOM   4726 C C   . SER B 1 346 ? 137.001 122.378 107.797 1.00 28.41  ? 420 SER B C   1 
ATOM   4727 O O   . SER B 1 346 ? 135.932 121.767 107.722 1.00 31.99  ? 420 SER B O   1 
ATOM   4728 C CB  . SER B 1 346 ? 139.152 121.085 107.752 1.00 27.58  ? 420 SER B CB  1 
ATOM   4729 O OG  . SER B 1 346 ? 140.179 120.564 106.927 1.00 31.74  ? 420 SER B OG  1 
ATOM   4730 N N   . LEU B 1 347 ? 137.163 123.420 108.613 1.00 33.96  ? 421 LEU B N   1 
ATOM   4731 C CA  . LEU B 1 347 ? 136.029 123.924 109.385 1.00 33.60  ? 421 LEU B CA  1 
ATOM   4732 C C   . LEU B 1 347 ? 134.918 124.422 108.470 1.00 35.23  ? 421 LEU B C   1 
ATOM   4733 O O   . LEU B 1 347 ? 133.731 124.229 108.757 1.00 41.93  ? 421 LEU B O   1 
ATOM   4734 C CB  . LEU B 1 347 ? 136.481 125.039 110.328 1.00 34.35  ? 421 LEU B CB  1 
ATOM   4735 C CG  . LEU B 1 347 ? 137.389 124.649 111.493 1.00 32.05  ? 421 LEU B CG  1 
ATOM   4736 C CD1 . LEU B 1 347 ? 137.851 125.887 112.240 1.00 32.20  ? 421 LEU B CD1 1 
ATOM   4737 C CD2 . LEU B 1 347 ? 136.677 123.692 112.430 1.00 33.37  ? 421 LEU B CD2 1 
ATOM   4738 N N   . ALA B 1 348 ? 135.285 125.070 107.363 1.00 35.34  ? 422 ALA B N   1 
ATOM   4739 C CA  . ALA B 1 348 ? 134.293 125.657 106.472 1.00 26.93  ? 422 ALA B CA  1 
ATOM   4740 C C   . ALA B 1 348 ? 133.491 124.589 105.741 1.00 29.73  ? 422 ALA B C   1 
ATOM   4741 O O   . ALA B 1 348 ? 132.262 124.684 105.646 1.00 44.60  ? 422 ALA B O   1 
ATOM   4742 C CB  . ALA B 1 348 ? 134.974 126.594 105.475 1.00 33.20  ? 422 ALA B CB  1 
ATOM   4743 N N   . GLN B 1 349 ? 134.159 123.563 105.208 1.00 31.05  ? 423 GLN B N   1 
ATOM   4744 C CA  . GLN B 1 349 ? 133.427 122.610 104.377 1.00 27.26  ? 423 GLN B CA  1 
ATOM   4745 C C   . GLN B 1 349 ? 133.017 121.324 105.086 1.00 29.67  ? 423 GLN B C   1 
ATOM   4746 O O   . GLN B 1 349 ? 132.081 120.664 104.624 1.00 42.25  ? 423 GLN B O   1 
ATOM   4747 C CB  . GLN B 1 349 ? 134.218 122.255 103.114 1.00 29.97  ? 423 GLN B CB  1 
ATOM   4748 C CG  . GLN B 1 349 ? 134.827 123.446 102.405 1.00 34.46  ? 423 GLN B CG  1 
ATOM   4749 C CD  . GLN B 1 349 ? 135.833 123.032 101.359 1.00 37.68  ? 423 GLN B CD  1 
ATOM   4750 O OE1 . GLN B 1 349 ? 136.054 121.842 101.134 1.00 39.79  ? 423 GLN B OE1 1 
ATOM   4751 N NE2 . GLN B 1 349 ? 136.454 124.011 100.711 1.00 36.82  ? 423 GLN B NE2 1 
ATOM   4752 N N   . CYS B 1 350 ? 133.676 120.941 106.179 1.00 32.37  ? 424 CYS B N   1 
ATOM   4753 C CA  . CYS B 1 350 ? 133.239 119.765 106.924 1.00 31.90  ? 424 CYS B CA  1 
ATOM   4754 C C   . CYS B 1 350 ? 132.113 120.111 107.892 1.00 36.87  ? 424 CYS B C   1 
ATOM   4755 O O   . CYS B 1 350 ? 131.001 119.584 107.784 1.00 44.05  ? 424 CYS B O   1 
ATOM   4756 C CB  . CYS B 1 350 ? 134.415 119.143 107.685 1.00 35.38  ? 424 CYS B CB  1 
ATOM   4757 S SG  . CYS B 1 350 ? 135.917 118.876 106.722 1.00 50.56  ? 424 CYS B SG  1 
ATOM   4758 N N   . LEU B 1 351 ? 132.386 120.999 108.844 1.00 34.77  ? 425 LEU B N   1 
ATOM   4759 C CA  . LEU B 1 351 ? 131.446 121.322 109.908 1.00 28.37  ? 425 LEU B CA  1 
ATOM   4760 C C   . LEU B 1 351 ? 130.588 122.544 109.607 1.00 34.31  ? 425 LEU B C   1 
ATOM   4761 O O   . LEU B 1 351 ? 129.714 122.875 110.415 1.00 46.03  ? 425 LEU B O   1 
ATOM   4762 C CB  . LEU B 1 351 ? 132.194 121.537 111.229 1.00 32.37  ? 425 LEU B CB  1 
ATOM   4763 C CG  . LEU B 1 351 ? 132.683 120.311 112.008 1.00 33.96  ? 425 LEU B CG  1 
ATOM   4764 C CD1 . LEU B 1 351 ? 133.856 119.624 111.325 1.00 32.81  ? 425 LEU B CD1 1 
ATOM   4765 C CD2 . LEU B 1 351 ? 133.048 120.701 113.432 1.00 37.69  ? 425 LEU B CD2 1 
ATOM   4766 N N   . HIS B 1 352 ? 130.807 123.209 108.472 1.00 29.39  ? 426 HIS B N   1 
ATOM   4767 C CA  . HIS B 1 352 ? 130.070 124.419 108.104 1.00 29.99  ? 426 HIS B CA  1 
ATOM   4768 C C   . HIS B 1 352 ? 130.143 125.467 109.212 1.00 32.22  ? 426 HIS B C   1 
ATOM   4769 O O   . HIS B 1 352 ? 129.137 126.036 109.639 1.00 41.76  ? 426 HIS B O   1 
ATOM   4770 C CB  . HIS B 1 352 ? 128.621 124.092 107.744 1.00 32.11  ? 426 HIS B CB  1 
ATOM   4771 C CG  . HIS B 1 352 ? 128.486 123.028 106.702 1.00 34.39  ? 426 HIS B CG  1 
ATOM   4772 N ND1 . HIS B 1 352 ? 128.409 123.312 105.355 1.00 33.15  ? 426 HIS B ND1 1 
ATOM   4773 C CD2 . HIS B 1 352 ? 128.418 121.680 106.806 1.00 37.48  ? 426 HIS B CD2 1 
ATOM   4774 C CE1 . HIS B 1 352 ? 128.298 122.185 104.675 1.00 36.26  ? 426 HIS B CE1 1 
ATOM   4775 N NE2 . HIS B 1 352 ? 128.301 121.180 105.532 1.00 38.15  ? 426 HIS B NE2 1 
ATOM   4776 N N   . TRP B 1 353 ? 131.363 125.717 109.677 1.00 32.96  ? 427 TRP B N   1 
ATOM   4777 C CA  . TRP B 1 353 ? 131.594 126.670 110.755 1.00 27.27  ? 427 TRP B CA  1 
ATOM   4778 C C   . TRP B 1 353 ? 131.380 128.093 110.252 1.00 33.57  ? 427 TRP B C   1 
ATOM   4779 O O   . TRP B 1 353 ? 132.115 128.568 109.379 1.00 44.51  ? 427 TRP B O   1 
ATOM   4780 C CB  . TRP B 1 353 ? 133.007 126.486 111.303 1.00 32.72  ? 427 TRP B CB  1 
ATOM   4781 C CG  . TRP B 1 353 ? 133.456 127.533 112.271 1.00 34.56  ? 427 TRP B CG  1 
ATOM   4782 C CD1 . TRP B 1 353 ? 133.138 127.621 113.593 1.00 32.38  ? 427 TRP B CD1 1 
ATOM   4783 C CD2 . TRP B 1 353 ? 134.341 128.625 111.998 1.00 29.80  ? 427 TRP B CD2 1 
ATOM   4784 N NE1 . TRP B 1 353 ? 133.755 128.709 114.157 1.00 29.15  ? 427 TRP B NE1 1 
ATOM   4785 C CE2 . TRP B 1 353 ? 134.501 129.343 113.198 1.00 25.80  ? 427 TRP B CE2 1 
ATOM   4786 C CE3 . TRP B 1 353 ? 135.007 129.070 110.853 1.00 35.62  ? 427 TRP B CE3 1 
ATOM   4787 C CZ2 . TRP B 1 353 ? 135.300 130.478 113.286 1.00 28.96  ? 427 TRP B CZ2 1 
ATOM   4788 C CZ3 . TRP B 1 353 ? 135.797 130.199 110.943 1.00 33.32  ? 427 TRP B CZ3 1 
ATOM   4789 C CH2 . TRP B 1 353 ? 135.936 130.891 112.150 1.00 30.63  ? 427 TRP B CH2 1 
ATOM   4790 N N   . ASN B 1 354 ? 130.368 128.766 110.802 1.00 34.59  ? 428 ASN B N   1 
ATOM   4791 C CA  . ASN B 1 354 ? 130.049 130.159 110.482 1.00 31.79  ? 428 ASN B CA  1 
ATOM   4792 C C   . ASN B 1 354 ? 129.745 130.338 108.993 1.00 41.30  ? 428 ASN B C   1 
ATOM   4793 O O   . ASN B 1 354 ? 130.459 131.027 108.261 1.00 46.92  ? 428 ASN B O   1 
ATOM   4794 C CB  . ASN B 1 354 ? 131.176 131.094 110.928 1.00 32.14  ? 428 ASN B CB  1 
ATOM   4795 C CG  . ASN B 1 354 ? 130.748 132.547 110.966 1.00 37.90  ? 428 ASN B CG  1 
ATOM   4796 O OD1 . ASN B 1 354 ? 129.855 132.923 111.725 1.00 35.92  ? 428 ASN B OD1 1 
ATOM   4797 N ND2 . ASN B 1 354 ? 131.384 133.374 110.145 1.00 43.70  ? 428 ASN B ND2 1 
ATOM   4798 N N   . VAL B 1 355 ? 128.663 129.703 108.552 1.00 42.37  ? 429 VAL B N   1 
ATOM   4799 C CA  . VAL B 1 355 ? 128.179 129.833 107.183 1.00 42.10  ? 429 VAL B CA  1 
ATOM   4800 C C   . VAL B 1 355 ? 127.107 130.914 107.143 1.00 49.03  ? 429 VAL B C   1 
ATOM   4801 O O   . VAL B 1 355 ? 126.225 130.961 108.011 1.00 50.11  ? 429 VAL B O   1 
ATOM   4802 C CB  . VAL B 1 355 ? 127.648 128.493 106.643 1.00 44.81  ? 429 VAL B CB  1 
ATOM   4803 C CG1 . VAL B 1 355 ? 128.786 127.498 106.513 1.00 45.43  ? 429 VAL B CG1 1 
ATOM   4804 C CG2 . VAL B 1 355 ? 126.562 127.934 107.550 1.00 47.00  ? 429 VAL B CG2 1 
ATOM   4805 N N   . ARG B 1 356 ? 127.200 131.795 106.149 1.00 56.70  ? 430 ARG B N   1 
ATOM   4806 C CA  . ARG B 1 356 ? 126.273 132.913 105.977 1.00 52.99  ? 430 ARG B CA  1 
ATOM   4807 C C   . ARG B 1 356 ? 126.186 133.777 107.232 1.00 57.20  ? 430 ARG B C   1 
ATOM   4808 O O   . ARG B 1 356 ? 127.200 134.077 107.863 1.00 57.48  ? 430 ARG B O   1 
ATOM   4809 C CB  . ARG B 1 356 ? 124.881 132.408 105.592 1.00 54.96  ? 430 ARG B CB  1 
ATOM   4810 C CG  . ARG B 1 356 ? 123.852 133.513 105.411 1.00 55.94  ? 430 ARG B CG  1 
ATOM   4811 C CD  . ARG B 1 356 ? 122.500 133.115 105.977 1.00 55.22  ? 430 ARG B CD  1 
ATOM   4812 N NE  . ARG B 1 356 ? 121.444 134.030 105.561 1.00 57.82  ? 430 ARG B NE  1 
ATOM   4813 C CZ  . ARG B 1 356 ? 120.450 134.432 106.342 1.00 60.59  ? 430 ARG B CZ  1 
ATOM   4814 N NH1 . ARG B 1 356 ? 120.343 134.017 107.594 1.00 57.79  ? 430 ARG B NH1 1 
ATOM   4815 N NH2 . ARG B 1 356 ? 119.541 135.271 105.854 1.00 56.69  ? 430 ARG B NH2 1 
ATOM   4816 N N   . PHE C 1 8   ? 89.238  139.847 112.183 1.00 71.17  ? 74  PHE C N   1 
ATOM   4817 C CA  . PHE C 1 8   ? 90.552  140.423 112.442 1.00 71.41  ? 74  PHE C CA  1 
ATOM   4818 C C   . PHE C 1 8   ? 90.531  141.925 112.183 1.00 71.51  ? 74  PHE C C   1 
ATOM   4819 O O   . PHE C 1 8   ? 90.570  142.726 113.116 1.00 73.00  ? 74  PHE C O   1 
ATOM   4820 C CB  . PHE C 1 8   ? 91.617  139.747 111.575 1.00 70.77  ? 74  PHE C CB  1 
ATOM   4821 C CG  . PHE C 1 8   ? 91.862  138.307 111.929 1.00 73.87  ? 74  PHE C CG  1 
ATOM   4822 C CD1 . PHE C 1 8   ? 91.423  137.790 113.137 1.00 73.03  ? 74  PHE C CD1 1 
ATOM   4823 C CD2 . PHE C 1 8   ? 92.525  137.468 111.049 1.00 72.78  ? 74  PHE C CD2 1 
ATOM   4824 C CE1 . PHE C 1 8   ? 91.643  136.466 113.463 1.00 71.26  ? 74  PHE C CE1 1 
ATOM   4825 C CE2 . PHE C 1 8   ? 92.749  136.142 111.369 1.00 72.40  ? 74  PHE C CE2 1 
ATOM   4826 C CZ  . PHE C 1 8   ? 92.306  135.642 112.577 1.00 71.86  ? 74  PHE C CZ  1 
ATOM   4827 N N   . GLY C 1 9   ? 90.464  142.299 110.909 1.00 78.02  ? 75  GLY C N   1 
ATOM   4828 C CA  . GLY C 1 9   ? 90.351  143.686 110.531 1.00 79.94  ? 75  GLY C CA  1 
ATOM   4829 C C   . GLY C 1 9   ? 88.905  144.135 110.493 1.00 82.09  ? 75  GLY C C   1 
ATOM   4830 O O   . GLY C 1 9   ? 88.032  143.543 111.136 1.00 80.43  ? 75  GLY C O   1 
ATOM   4831 N N   . PRO C 1 10  ? 88.630  145.214 109.754 1.00 83.68  ? 76  PRO C N   1 
ATOM   4832 C CA  . PRO C 1 10  ? 87.231  145.649 109.599 1.00 83.18  ? 76  PRO C CA  1 
ATOM   4833 C C   . PRO C 1 10  ? 86.322  144.559 109.062 1.00 83.87  ? 76  PRO C C   1 
ATOM   4834 O O   . PRO C 1 10  ? 85.169  144.445 109.499 1.00 81.92  ? 76  PRO C O   1 
ATOM   4835 C CB  . PRO C 1 10  ? 87.332  146.823 108.614 1.00 81.25  ? 76  PRO C CB  1 
ATOM   4836 C CG  . PRO C 1 10  ? 88.751  147.270 108.646 1.00 79.22  ? 76  PRO C CG  1 
ATOM   4837 C CD  . PRO C 1 10  ? 89.595  146.245 109.340 1.00 78.77  ? 76  PRO C CD  1 
ATOM   4838 N N   . LYS C 1 11  ? 86.810  143.749 108.123 1.00 84.52  ? 77  LYS C N   1 
ATOM   4839 C CA  . LYS C 1 11  ? 86.014  142.681 107.532 1.00 84.01  ? 77  LYS C CA  1 
ATOM   4840 C C   . LYS C 1 11  ? 86.675  141.313 107.578 1.00 83.08  ? 77  LYS C C   1 
ATOM   4841 O O   . LYS C 1 11  ? 85.972  140.310 107.406 1.00 82.42  ? 77  LYS C O   1 
ATOM   4842 C CB  . LYS C 1 11  ? 85.673  143.012 106.071 1.00 82.32  ? 77  LYS C CB  1 
ATOM   4843 C CG  . LYS C 1 11  ? 84.873  144.294 105.897 1.00 81.91  ? 77  LYS C CG  1 
ATOM   4844 C CD  . LYS C 1 11  ? 83.493  144.175 106.520 1.00 82.03  ? 77  LYS C CD  1 
ATOM   4845 C CE  . LYS C 1 11  ? 82.638  145.391 106.200 1.00 82.31  ? 77  LYS C CE  1 
ATOM   4846 N NZ  . LYS C 1 11  ? 83.133  146.613 106.891 1.00 82.44  ? 77  LYS C NZ  1 
ATOM   4847 N N   . ALA C 1 12  ? 87.983  141.230 107.801 1.00 81.66  ? 78  ALA C N   1 
ATOM   4848 C CA  . ALA C 1 12  ? 88.674  139.947 107.846 1.00 83.20  ? 78  ALA C CA  1 
ATOM   4849 C C   . ALA C 1 12  ? 88.323  139.178 109.116 1.00 83.30  ? 78  ALA C C   1 
ATOM   4850 O O   . ALA C 1 12  ? 87.840  139.756 110.089 1.00 82.45  ? 78  ALA C O   1 
ATOM   4851 C CB  . ALA C 1 12  ? 90.177  140.152 107.750 1.00 81.84  ? 78  ALA C CB  1 
ATOM   4852 N N   . VAL C 1 22  ? 94.094  126.401 110.215 1.00 52.22  ? 96  VAL C N   1 
ATOM   4853 C CA  . VAL C 1 22  ? 93.410  127.679 110.364 1.00 52.33  ? 96  VAL C CA  1 
ATOM   4854 C C   . VAL C 1 22  ? 93.352  128.399 109.023 1.00 53.90  ? 96  VAL C C   1 
ATOM   4855 O O   . VAL C 1 22  ? 94.374  128.841 108.501 1.00 54.89  ? 96  VAL C O   1 
ATOM   4856 C CB  . VAL C 1 22  ? 94.094  128.556 111.426 1.00 54.31  ? 96  VAL C CB  1 
ATOM   4857 C CG1 . VAL C 1 22  ? 93.413  129.912 111.514 1.00 53.46  ? 96  VAL C CG1 1 
ATOM   4858 C CG2 . VAL C 1 22  ? 94.081  127.858 112.777 1.00 53.37  ? 96  VAL C CG2 1 
ATOM   4859 N N   . ARG C 1 23  ? 92.150  128.515 108.471 1.00 58.59  ? 97  ARG C N   1 
ATOM   4860 C CA  . ARG C 1 23  ? 91.937  129.146 107.178 1.00 56.93  ? 97  ARG C CA  1 
ATOM   4861 C C   . ARG C 1 23  ? 91.576  130.617 107.353 1.00 59.08  ? 97  ARG C C   1 
ATOM   4862 O O   . ARG C 1 23  ? 91.391  131.115 108.465 1.00 63.21  ? 97  ARG C O   1 
ATOM   4863 C CB  . ARG C 1 23  ? 90.840  128.416 106.397 1.00 57.00  ? 97  ARG C CB  1 
ATOM   4864 C CG  . ARG C 1 23  ? 90.991  126.904 106.380 1.00 59.32  ? 97  ARG C CG  1 
ATOM   4865 C CD  . ARG C 1 23  ? 92.267  126.483 105.673 1.00 57.92  ? 97  ARG C CD  1 
ATOM   4866 N NE  . ARG C 1 23  ? 92.379  127.077 104.346 1.00 57.74  ? 97  ARG C NE  1 
ATOM   4867 C CZ  . ARG C 1 23  ? 93.149  126.602 103.377 1.00 59.73  ? 97  ARG C CZ  1 
ATOM   4868 N NH1 . ARG C 1 23  ? 93.893  125.522 103.551 1.00 58.56  ? 97  ARG C NH1 1 
ATOM   4869 N NH2 . ARG C 1 23  ? 93.173  127.226 102.202 1.00 58.72  ? 97  ARG C NH2 1 
ATOM   4870 N N   . LEU C 1 24  ? 91.477  131.313 106.225 1.00 56.31  ? 98  LEU C N   1 
ATOM   4871 C CA  . LEU C 1 24  ? 91.142  132.730 106.193 1.00 54.87  ? 98  LEU C CA  1 
ATOM   4872 C C   . LEU C 1 24  ? 89.805  132.919 105.491 1.00 57.22  ? 98  LEU C C   1 
ATOM   4873 O O   . LEU C 1 24  ? 89.618  132.447 104.365 1.00 57.70  ? 98  LEU C O   1 
ATOM   4874 C CB  . LEU C 1 24  ? 92.237  133.531 105.485 1.00 52.25  ? 98  LEU C CB  1 
ATOM   4875 C CG  . LEU C 1 24  ? 92.110  135.054 105.504 1.00 52.41  ? 98  LEU C CG  1 
ATOM   4876 C CD1 . LEU C 1 24  ? 92.439  135.603 106.883 1.00 53.85  ? 98  LEU C CD1 1 
ATOM   4877 C CD2 . LEU C 1 24  ? 93.015  135.671 104.451 1.00 53.17  ? 98  LEU C CD2 1 
ATOM   4878 N N   . THR C 1 25  ? 88.883  133.610 106.156 1.00 61.19  ? 99  THR C N   1 
ATOM   4879 C CA  . THR C 1 25  ? 87.562  133.899 105.617 1.00 60.37  ? 99  THR C CA  1 
ATOM   4880 C C   . THR C 1 25  ? 87.370  135.407 105.550 1.00 59.76  ? 99  THR C C   1 
ATOM   4881 O O   . THR C 1 25  ? 87.688  136.126 106.503 1.00 64.03  ? 99  THR C O   1 
ATOM   4882 C CB  . THR C 1 25  ? 86.460  133.262 106.473 1.00 63.35  ? 99  THR C CB  1 
ATOM   4883 O OG1 . THR C 1 25  ? 86.666  131.846 106.543 1.00 62.04  ? 99  THR C OG1 1 
ATOM   4884 C CG2 . THR C 1 25  ? 85.088  133.537 105.875 1.00 61.23  ? 99  THR C CG2 1 
ATOM   4885 N N   . TRP C 1 26  ? 86.849  135.884 104.421 1.00 57.90  ? 100 TRP C N   1 
ATOM   4886 C CA  . TRP C 1 26  ? 86.744  137.315 104.167 1.00 59.86  ? 100 TRP C CA  1 
ATOM   4887 C C   . TRP C 1 26  ? 85.398  137.911 104.548 1.00 60.89  ? 100 TRP C C   1 
ATOM   4888 O O   . TRP C 1 26  ? 85.343  139.095 104.897 1.00 64.56  ? 100 TRP C O   1 
ATOM   4889 C CB  . TRP C 1 26  ? 87.010  137.611 102.686 1.00 59.93  ? 100 TRP C CB  1 
ATOM   4890 C CG  . TRP C 1 26  ? 88.462  137.618 102.321 1.00 57.86  ? 100 TRP C CG  1 
ATOM   4891 C CD1 . TRP C 1 26  ? 89.073  136.836 101.387 1.00 56.76  ? 100 TRP C CD1 1 
ATOM   4892 C CD2 . TRP C 1 26  ? 89.485  138.451 102.878 1.00 53.44  ? 100 TRP C CD2 1 
ATOM   4893 N NE1 . TRP C 1 26  ? 90.414  137.127 101.329 1.00 59.19  ? 100 TRP C NE1 1 
ATOM   4894 C CE2 . TRP C 1 26  ? 90.692  138.116 102.235 1.00 56.53  ? 100 TRP C CE2 1 
ATOM   4895 C CE3 . TRP C 1 26  ? 89.498  139.447 103.859 1.00 55.42  ? 100 TRP C CE3 1 
ATOM   4896 C CZ2 . TRP C 1 26  ? 91.898  138.741 102.540 1.00 58.22  ? 100 TRP C CZ2 1 
ATOM   4897 C CZ3 . TRP C 1 26  ? 90.695  140.064 104.160 1.00 57.52  ? 100 TRP C CZ3 1 
ATOM   4898 C CH2 . TRP C 1 26  ? 91.879  139.709 103.504 1.00 57.23  ? 100 TRP C CH2 1 
ATOM   4899 N N   . ASN C 1 27  ? 84.316  137.132 104.464 1.00 71.96  ? 101 ASN C N   1 
ATOM   4900 C CA  . ASN C 1 27  ? 82.960  137.620 104.704 1.00 74.14  ? 101 ASN C CA  1 
ATOM   4901 C C   . ASN C 1 27  ? 82.603  138.685 103.674 1.00 72.54  ? 101 ASN C C   1 
ATOM   4902 O O   . ASN C 1 27  ? 81.770  138.452 102.792 1.00 71.57  ? 101 ASN C O   1 
ATOM   4903 C CB  . ASN C 1 27  ? 82.807  138.160 106.131 1.00 72.82  ? 101 ASN C CB  1 
ATOM   4904 C CG  . ASN C 1 27  ? 81.471  138.842 106.360 1.00 74.22  ? 101 ASN C CG  1 
ATOM   4905 O OD1 . ASN C 1 27  ? 81.302  140.022 106.051 1.00 74.64  ? 101 ASN C OD1 1 
ATOM   4906 N ND2 . ASN C 1 27  ? 80.514  138.101 106.906 1.00 72.85  ? 101 ASN C ND2 1 
ATOM   4907 N N   . LYS C 1 28  ? 83.227  139.854 103.779 1.00 71.30  ? 102 LYS C N   1 
ATOM   4908 C CA  . LYS C 1 28  ? 83.115  140.901 102.777 1.00 71.19  ? 102 LYS C CA  1 
ATOM   4909 C C   . LYS C 1 28  ? 84.378  140.933 101.925 1.00 69.49  ? 102 LYS C C   1 
ATOM   4910 O O   . LYS C 1 28  ? 85.481  140.671 102.410 1.00 69.95  ? 102 LYS C O   1 
ATOM   4911 C CB  . LYS C 1 28  ? 82.878  142.261 103.434 1.00 72.19  ? 102 LYS C CB  1 
ATOM   4912 C CG  . LYS C 1 28  ? 81.599  142.342 104.252 1.00 73.08  ? 102 LYS C CG  1 
ATOM   4913 C CD  . LYS C 1 28  ? 80.370  142.170 103.376 1.00 73.45  ? 102 LYS C CD  1 
ATOM   4914 C CE  . LYS C 1 28  ? 79.090  142.324 104.181 1.00 72.09  ? 102 LYS C CE  1 
ATOM   4915 N NZ  . LYS C 1 28  ? 77.878  142.133 103.339 1.00 71.84  ? 102 LYS C NZ  1 
ATOM   4916 N N   . SER C 1 29  ? 84.203  141.245 100.647 1.00 64.20  ? 103 SER C N   1 
ATOM   4917 C CA  . SER C 1 29  ? 85.331  141.257 99.723  1.00 65.77  ? 103 SER C CA  1 
ATOM   4918 C C   . SER C 1 29  ? 86.323  142.345 100.123 1.00 66.35  ? 103 SER C C   1 
ATOM   4919 O O   . SER C 1 29  ? 85.917  143.488 100.363 1.00 68.24  ? 103 SER C O   1 
ATOM   4920 C CB  . SER C 1 29  ? 84.847  141.482 98.293  1.00 63.65  ? 103 SER C CB  1 
ATOM   4921 O OG  . SER C 1 29  ? 85.932  141.474 97.381  1.00 63.28  ? 103 SER C OG  1 
ATOM   4922 N N   . PRO C 1 30  ? 87.615  142.033 100.217 1.00 52.86  ? 104 PRO C N   1 
ATOM   4923 C CA  . PRO C 1 30  ? 88.593  143.055 100.604 1.00 50.09  ? 104 PRO C CA  1 
ATOM   4924 C C   . PRO C 1 30  ? 88.677  144.169 99.571  1.00 49.22  ? 104 PRO C C   1 
ATOM   4925 O O   . PRO C 1 30  ? 88.651  143.927 98.363  1.00 52.32  ? 104 PRO C O   1 
ATOM   4926 C CB  . PRO C 1 30  ? 89.905  142.269 100.697 1.00 51.25  ? 104 PRO C CB  1 
ATOM   4927 C CG  . PRO C 1 30  ? 89.698  141.099 99.792  1.00 52.24  ? 104 PRO C CG  1 
ATOM   4928 C CD  . PRO C 1 30  ? 88.253  140.732 99.957  1.00 51.89  ? 104 PRO C CD  1 
ATOM   4929 N N   . LYS C 1 31  ? 88.779  145.403 100.064 1.00 52.01  ? 105 LYS C N   1 
ATOM   4930 C CA  . LYS C 1 31  ? 88.867  146.575 99.203  1.00 52.88  ? 105 LYS C CA  1 
ATOM   4931 C C   . LYS C 1 31  ? 89.902  147.598 99.642  1.00 53.32  ? 105 LYS C C   1 
ATOM   4932 O O   . LYS C 1 31  ? 90.211  148.502 98.856  1.00 58.76  ? 105 LYS C O   1 
ATOM   4933 C CB  . LYS C 1 31  ? 87.498  147.250 99.113  1.00 56.74  ? 105 LYS C CB  1 
ATOM   4934 C CG  . LYS C 1 31  ? 86.434  146.411 98.422  1.00 56.10  ? 105 LYS C CG  1 
ATOM   4935 C CD  . LYS C 1 31  ? 85.097  147.130 98.390  1.00 55.70  ? 105 LYS C CD  1 
ATOM   4936 C CE  . LYS C 1 31  ? 84.040  146.301 97.679  1.00 56.61  ? 105 LYS C CE  1 
ATOM   4937 N NZ  . LYS C 1 31  ? 82.717  146.984 97.661  1.00 56.93  ? 105 LYS C NZ  1 
ATOM   4938 N N   . SER C 1 32  ? 90.441  147.502 100.854 1.00 44.67  ? 106 SER C N   1 
ATOM   4939 C CA  . SER C 1 32  ? 91.403  148.468 101.375 1.00 40.77  ? 106 SER C CA  1 
ATOM   4940 C C   . SER C 1 32  ? 92.661  147.722 101.796 1.00 44.33  ? 106 SER C C   1 
ATOM   4941 O O   . SER C 1 32  ? 92.661  147.022 102.814 1.00 52.86  ? 106 SER C O   1 
ATOM   4942 C CB  . SER C 1 32  ? 90.808  149.251 102.543 1.00 49.52  ? 106 SER C CB  1 
ATOM   4943 O OG  . SER C 1 32  ? 91.760  150.140 103.098 1.00 51.16  ? 106 SER C OG  1 
ATOM   4944 N N   . VAL C 1 33  ? 93.733  147.881 101.026 1.00 32.55  ? 107 VAL C N   1 
ATOM   4945 C CA  . VAL C 1 33  ? 94.993  147.195 101.275 1.00 28.75  ? 107 VAL C CA  1 
ATOM   4946 C C   . VAL C 1 33  ? 96.066  148.232 101.578 1.00 34.93  ? 107 VAL C C   1 
ATOM   4947 O O   . VAL C 1 33  ? 96.103  149.303 100.964 1.00 45.07  ? 107 VAL C O   1 
ATOM   4948 C CB  . VAL C 1 33  ? 95.399  146.301 100.083 1.00 33.34  ? 107 VAL C CB  1 
ATOM   4949 C CG1 . VAL C 1 33  ? 95.619  147.130 98.834  1.00 39.49  ? 107 VAL C CG1 1 
ATOM   4950 C CG2 . VAL C 1 33  ? 96.645  145.494 100.415 1.00 40.10  ? 107 VAL C CG2 1 
ATOM   4951 N N   . LEU C 1 34  ? 96.919  147.925 102.550 1.00 34.06  ? 108 LEU C N   1 
ATOM   4952 C CA  . LEU C 1 34  ? 98.046  148.772 102.907 1.00 30.01  ? 108 LEU C CA  1 
ATOM   4953 C C   . LEU C 1 34  ? 99.334  148.103 102.453 1.00 33.58  ? 108 LEU C C   1 
ATOM   4954 O O   . LEU C 1 34  ? 99.603  146.954 102.818 1.00 40.10  ? 108 LEU C O   1 
ATOM   4955 C CB  . LEU C 1 34  ? 98.087  149.032 104.414 1.00 36.07  ? 108 LEU C CB  1 
ATOM   4956 C CG  . LEU C 1 34  ? 99.417  149.518 104.994 1.00 37.92  ? 108 LEU C CG  1 
ATOM   4957 C CD1 . LEU C 1 34  ? 99.729  150.923 104.513 1.00 41.65  ? 108 LEU C CD1 1 
ATOM   4958 C CD2 . LEU C 1 34  ? 99.398  149.461 106.511 1.00 39.18  ? 108 LEU C CD2 1 
ATOM   4959 N N   . VAL C 1 35  ? 100.121 148.819 101.657 1.00 32.09  ? 109 VAL C N   1 
ATOM   4960 C CA  . VAL C 1 35  ? 101.401 148.331 101.160 1.00 26.68  ? 109 VAL C CA  1 
ATOM   4961 C C   . VAL C 1 35  ? 102.497 149.067 101.915 1.00 29.95  ? 109 VAL C C   1 
ATOM   4962 O O   . VAL C 1 35  ? 102.615 150.294 101.814 1.00 40.04  ? 109 VAL C O   1 
ATOM   4963 C CB  . VAL C 1 35  ? 101.538 148.534 99.644  1.00 26.80  ? 109 VAL C CB  1 
ATOM   4964 C CG1 . VAL C 1 35  ? 102.976 148.315 99.209  1.00 35.78  ? 109 VAL C CG1 1 
ATOM   4965 C CG2 . VAL C 1 35  ? 100.603 147.599 98.899  1.00 32.73  ? 109 VAL C CG2 1 
ATOM   4966 N N   . ILE C 1 36  ? 103.295 148.321 102.673 1.00 38.92  ? 110 ILE C N   1 
ATOM   4967 C CA  . ILE C 1 36  ? 104.355 148.884 103.498 1.00 34.47  ? 110 ILE C CA  1 
ATOM   4968 C C   . ILE C 1 36  ? 105.682 148.589 102.815 1.00 35.09  ? 110 ILE C C   1 
ATOM   4969 O O   . ILE C 1 36  ? 106.023 147.423 102.579 1.00 40.14  ? 110 ILE C O   1 
ATOM   4970 C CB  . ILE C 1 36  ? 104.326 148.320 104.926 1.00 35.68  ? 110 ILE C CB  1 
ATOM   4971 C CG1 . ILE C 1 36  ? 103.023 148.713 105.621 1.00 34.23  ? 110 ILE C CG1 1 
ATOM   4972 C CG2 . ILE C 1 36  ? 105.502 148.849 105.723 1.00 40.87  ? 110 ILE C CG2 1 
ATOM   4973 C CD1 . ILE C 1 36  ? 102.967 148.327 107.082 1.00 39.05  ? 110 ILE C CD1 1 
ATOM   4974 N N   . LYS C 1 37  ? 106.424 149.642 102.497 1.00 45.57  ? 111 LYS C N   1 
ATOM   4975 C CA  . LYS C 1 37  ? 107.680 149.543 101.773 1.00 48.18  ? 111 LYS C CA  1 
ATOM   4976 C C   . LYS C 1 37  ? 108.854 149.757 102.720 1.00 53.71  ? 111 LYS C C   1 
ATOM   4977 O O   . LYS C 1 37  ? 108.777 150.544 103.666 1.00 56.62  ? 111 LYS C O   1 
ATOM   4978 C CB  . LYS C 1 37  ? 107.725 150.571 100.640 1.00 49.47  ? 111 LYS C CB  1 
ATOM   4979 C CG  . LYS C 1 37  ? 108.961 150.499 99.762  1.00 50.22  ? 111 LYS C CG  1 
ATOM   4980 C CD  . LYS C 1 37  ? 108.890 151.518 98.639  1.00 50.98  ? 111 LYS C CD  1 
ATOM   4981 C CE  . LYS C 1 37  ? 110.078 151.391 97.704  1.00 52.60  ? 111 LYS C CE  1 
ATOM   4982 N NZ  . LYS C 1 37  ? 111.347 151.779 98.378  1.00 53.30  ? 111 LYS C NZ  1 
ATOM   4983 N N   . LYS C 1 38  ? 109.944 149.040 102.459 1.00 60.37  ? 112 LYS C N   1 
ATOM   4984 C CA  . LYS C 1 38  ? 111.164 149.215 103.236 1.00 61.00  ? 112 LYS C CA  1 
ATOM   4985 C C   . LYS C 1 38  ? 111.837 150.524 102.841 1.00 67.84  ? 112 LYS C C   1 
ATOM   4986 O O   . LYS C 1 38  ? 112.247 150.696 101.689 1.00 69.04  ? 112 LYS C O   1 
ATOM   4987 C CB  . LYS C 1 38  ? 112.104 148.034 103.013 1.00 60.48  ? 112 LYS C CB  1 
ATOM   4988 C CG  . LYS C 1 38  ? 113.371 148.077 103.847 1.00 60.36  ? 112 LYS C CG  1 
ATOM   4989 C CD  . LYS C 1 38  ? 114.227 146.846 103.604 1.00 62.99  ? 112 LYS C CD  1 
ATOM   4990 C CE  . LYS C 1 38  ? 115.451 146.838 104.503 1.00 66.64  ? 112 LYS C CE  1 
ATOM   4991 N NZ  . LYS C 1 38  ? 116.402 147.930 104.153 1.00 66.31  ? 112 LYS C NZ  1 
ATOM   4992 N N   . MET C 1 39  ? 111.947 151.445 103.794 1.00 76.10  ? 113 MET C N   1 
ATOM   4993 C CA  . MET C 1 39  ? 112.510 152.755 103.513 1.00 74.30  ? 113 MET C CA  1 
ATOM   4994 C C   . MET C 1 39  ? 114.008 152.656 103.235 1.00 77.97  ? 113 MET C C   1 
ATOM   4995 O O   . MET C 1 39  ? 114.685 151.707 103.643 1.00 79.94  ? 113 MET C O   1 
ATOM   4996 C CB  . MET C 1 39  ? 112.260 153.712 104.679 1.00 74.38  ? 113 MET C CB  1 
ATOM   4997 C CG  . MET C 1 39  ? 110.847 154.266 104.748 1.00 76.99  ? 113 MET C CG  1 
ATOM   4998 S SD  . MET C 1 39  ? 109.639 153.060 105.327 1.00 85.07  ? 113 MET C SD  1 
ATOM   4999 C CE  . MET C 1 39  ? 110.031 152.994 107.073 1.00 75.10  ? 113 MET C CE  1 
ATOM   5000 N N   . ARG C 1 40  ? 114.520 153.665 102.526 1.00 81.88  ? 114 ARG C N   1 
ATOM   5001 C CA  . ARG C 1 40  ? 115.943 153.776 102.201 1.00 82.61  ? 114 ARG C CA  1 
ATOM   5002 C C   . ARG C 1 40  ? 116.440 152.545 101.444 1.00 81.48  ? 114 ARG C C   1 
ATOM   5003 O O   . ARG C 1 40  ? 117.487 151.974 101.755 1.00 82.12  ? 114 ARG C O   1 
ATOM   5004 C CB  . ARG C 1 40  ? 116.768 153.977 103.474 1.00 82.15  ? 114 ARG C CB  1 
ATOM   5005 C CG  . ARG C 1 40  ? 116.520 155.305 104.170 1.00 81.66  ? 114 ARG C CG  1 
ATOM   5006 C CD  . ARG C 1 40  ? 117.374 155.526 105.409 1.00 82.43  ? 114 ARG C CD  1 
ATOM   5007 N NE  . ARG C 1 40  ? 117.052 156.782 106.080 1.00 83.11  ? 114 ARG C NE  1 
ATOM   5008 C CZ  . ARG C 1 40  ? 117.566 157.159 107.241 1.00 83.66  ? 114 ARG C CZ  1 
ATOM   5009 N NH1 . ARG C 1 40  ? 118.437 156.379 107.868 1.00 84.86  ? 114 ARG C NH1 1 
ATOM   5010 N NH2 . ARG C 1 40  ? 117.215 158.320 107.779 1.00 81.24  ? 114 ARG C NH2 1 
ATOM   5011 N N   . ASP C 1 41  ? 115.673 152.137 100.437 1.00 68.44  ? 115 ASP C N   1 
ATOM   5012 C CA  . ASP C 1 41  ? 116.036 151.021 99.578  1.00 69.24  ? 115 ASP C CA  1 
ATOM   5013 C C   . ASP C 1 41  ? 115.800 151.420 98.129  1.00 69.97  ? 115 ASP C C   1 
ATOM   5014 O O   . ASP C 1 41  ? 114.955 152.269 97.833  1.00 69.53  ? 115 ASP C O   1 
ATOM   5015 C CB  . ASP C 1 41  ? 115.231 149.757 99.928  1.00 71.63  ? 115 ASP C CB  1 
ATOM   5016 C CG  . ASP C 1 41  ? 115.766 148.510 99.243  1.00 73.70  ? 115 ASP C CG  1 
ATOM   5017 O OD1 . ASP C 1 41  ? 115.884 148.503 98.000  1.00 72.45  ? 115 ASP C OD1 1 
ATOM   5018 O OD2 . ASP C 1 41  ? 116.072 147.531 99.956  1.00 74.19  ? 115 ASP C OD2 1 
ATOM   5019 N N   . ALA C 1 42  ? 116.560 150.800 97.226  1.00 61.84  ? 116 ALA C N   1 
ATOM   5020 C CA  . ALA C 1 42  ? 116.491 151.118 95.806  1.00 61.32  ? 116 ALA C CA  1 
ATOM   5021 C C   . ALA C 1 42  ? 115.981 149.977 94.943  1.00 60.90  ? 116 ALA C C   1 
ATOM   5022 O O   . ALA C 1 42  ? 115.360 150.235 93.910  1.00 65.15  ? 116 ALA C O   1 
ATOM   5023 C CB  . ALA C 1 42  ? 117.870 151.549 95.290  1.00 64.66  ? 116 ALA C CB  1 
ATOM   5024 N N   . SER C 1 43  ? 116.223 148.727 95.335  1.00 55.48  ? 117 SER C N   1 
ATOM   5025 C CA  . SER C 1 43  ? 115.765 147.585 94.555  1.00 56.23  ? 117 SER C CA  1 
ATOM   5026 C C   . SER C 1 43  ? 114.268 147.343 94.680  1.00 56.44  ? 117 SER C C   1 
ATOM   5027 O O   . SER C 1 43  ? 113.724 146.534 93.921  1.00 57.38  ? 117 SER C O   1 
ATOM   5028 C CB  . SER C 1 43  ? 116.521 146.323 94.976  1.00 55.84  ? 117 SER C CB  1 
ATOM   5029 O OG  . SER C 1 43  ? 116.061 145.191 94.259  1.00 57.82  ? 117 SER C OG  1 
ATOM   5030 N N   . LEU C 1 44  ? 113.594 148.017 95.609  1.00 53.87  ? 118 LEU C N   1 
ATOM   5031 C CA  . LEU C 1 44  ? 112.175 147.799 95.846  1.00 50.43  ? 118 LEU C CA  1 
ATOM   5032 C C   . LEU C 1 44  ? 111.276 148.729 95.045  1.00 54.33  ? 118 LEU C C   1 
ATOM   5033 O O   . LEU C 1 44  ? 110.056 148.539 95.060  1.00 58.15  ? 118 LEU C O   1 
ATOM   5034 C CB  . LEU C 1 44  ? 111.859 147.966 97.336  1.00 52.20  ? 118 LEU C CB  1 
ATOM   5035 C CG  . LEU C 1 44  ? 111.864 146.715 98.214  1.00 48.97  ? 118 LEU C CG  1 
ATOM   5036 C CD1 . LEU C 1 44  ? 113.250 146.096 98.286  1.00 49.95  ? 118 LEU C CD1 1 
ATOM   5037 C CD2 . LEU C 1 44  ? 111.348 147.051 99.600  1.00 52.77  ? 118 LEU C CD2 1 
ATOM   5038 N N   . LEU C 1 45  ? 111.836 149.723 94.351  1.00 54.28  ? 119 LEU C N   1 
ATOM   5039 C CA  . LEU C 1 45  ? 111.001 150.711 93.670  1.00 48.89  ? 119 LEU C CA  1 
ATOM   5040 C C   . LEU C 1 45  ? 110.183 150.076 92.553  1.00 52.58  ? 119 LEU C C   1 
ATOM   5041 O O   . LEU C 1 45  ? 108.958 150.230 92.504  1.00 55.45  ? 119 LEU C O   1 
ATOM   5042 C CB  . LEU C 1 45  ? 111.862 151.851 93.123  1.00 47.15  ? 119 LEU C CB  1 
ATOM   5043 C CG  . LEU C 1 45  ? 112.257 152.990 94.070  1.00 56.31  ? 119 LEU C CG  1 
ATOM   5044 C CD1 . LEU C 1 45  ? 111.019 153.745 94.535  1.00 54.95  ? 119 LEU C CD1 1 
ATOM   5045 C CD2 . LEU C 1 45  ? 113.071 152.502 95.258  1.00 57.11  ? 119 LEU C CD2 1 
ATOM   5046 N N   . GLN C 1 46  ? 110.842 149.352 91.649  1.00 51.17  ? 120 GLN C N   1 
ATOM   5047 C CA  . GLN C 1 46  ? 110.123 148.739 90.532  1.00 49.70  ? 120 GLN C CA  1 
ATOM   5048 C C   . GLN C 1 46  ? 109.068 147.740 90.990  1.00 49.99  ? 120 GLN C C   1 
ATOM   5049 O O   . GLN C 1 46  ? 107.925 147.817 90.502  1.00 54.35  ? 120 GLN C O   1 
ATOM   5050 C CB  . GLN C 1 46  ? 111.123 148.103 89.561  1.00 48.66  ? 120 GLN C CB  1 
ATOM   5051 C CG  . GLN C 1 46  ? 110.485 147.491 88.325  1.00 52.61  ? 120 GLN C CG  1 
ATOM   5052 C CD  . GLN C 1 46  ? 109.757 148.514 87.478  1.00 57.18  ? 120 GLN C CD  1 
ATOM   5053 O OE1 . GLN C 1 46  ? 108.527 148.575 87.478  1.00 55.30  ? 120 GLN C OE1 1 
ATOM   5054 N NE2 . GLN C 1 46  ? 110.514 149.326 86.749  1.00 56.95  ? 120 GLN C NE2 1 
ATOM   5055 N N   . PRO C 1 47  ? 109.357 146.792 91.891  1.00 45.43  ? 121 PRO C N   1 
ATOM   5056 C CA  . PRO C 1 47  ? 108.275 145.931 92.390  1.00 46.63  ? 121 PRO C CA  1 
ATOM   5057 C C   . PRO C 1 47  ? 107.177 146.696 93.101  1.00 44.50  ? 121 PRO C C   1 
ATOM   5058 O O   . PRO C 1 47  ? 106.006 146.313 92.996  1.00 49.55  ? 121 PRO C O   1 
ATOM   5059 C CB  . PRO C 1 47  ? 109.005 144.974 93.340  1.00 44.42  ? 121 PRO C CB  1 
ATOM   5060 C CG  . PRO C 1 47  ? 110.402 144.959 92.848  1.00 47.08  ? 121 PRO C CG  1 
ATOM   5061 C CD  . PRO C 1 47  ? 110.658 146.374 92.442  1.00 48.18  ? 121 PRO C CD  1 
ATOM   5062 N N   . PHE C 1 48  ? 107.514 147.770 93.819  1.00 37.31  ? 122 PHE C N   1 
ATOM   5063 C CA  . PHE C 1 48  ? 106.488 148.562 94.489  1.00 33.24  ? 122 PHE C CA  1 
ATOM   5064 C C   . PHE C 1 48  ? 105.539 149.192 93.478  1.00 46.56  ? 122 PHE C C   1 
ATOM   5065 O O   . PHE C 1 48  ? 104.315 149.136 93.642  1.00 54.47  ? 122 PHE C O   1 
ATOM   5066 C CB  . PHE C 1 48  ? 107.137 149.637 95.362  1.00 40.89  ? 122 PHE C CB  1 
ATOM   5067 C CG  . PHE C 1 48  ? 106.159 150.601 95.972  1.00 39.00  ? 122 PHE C CG  1 
ATOM   5068 C CD1 . PHE C 1 48  ? 105.421 150.247 97.087  1.00 40.35  ? 122 PHE C CD1 1 
ATOM   5069 C CD2 . PHE C 1 48  ? 105.987 151.866 95.437  1.00 39.99  ? 122 PHE C CD2 1 
ATOM   5070 C CE1 . PHE C 1 48  ? 104.525 151.133 97.651  1.00 39.23  ? 122 PHE C CE1 1 
ATOM   5071 C CE2 . PHE C 1 48  ? 105.092 152.755 95.998  1.00 36.19  ? 122 PHE C CE2 1 
ATOM   5072 C CZ  . PHE C 1 48  ? 104.361 152.387 97.106  1.00 39.17  ? 122 PHE C CZ  1 
ATOM   5073 N N   . LYS C 1 49  ? 106.088 149.793 92.419  1.00 54.31  ? 123 LYS C N   1 
ATOM   5074 C CA  . LYS C 1 49  ? 105.240 150.380 91.386  1.00 52.24  ? 123 LYS C CA  1 
ATOM   5075 C C   . LYS C 1 49  ? 104.409 149.317 90.682  1.00 49.89  ? 123 LYS C C   1 
ATOM   5076 O O   . LYS C 1 49  ? 103.222 149.530 90.413  1.00 57.32  ? 123 LYS C O   1 
ATOM   5077 C CB  . LYS C 1 49  ? 106.084 151.156 90.374  1.00 53.77  ? 123 LYS C CB  1 
ATOM   5078 C CG  . LYS C 1 49  ? 107.047 152.155 90.987  1.00 54.30  ? 123 LYS C CG  1 
ATOM   5079 C CD  . LYS C 1 49  ? 108.063 152.631 89.963  1.00 54.77  ? 123 LYS C CD  1 
ATOM   5080 C CE  . LYS C 1 49  ? 108.907 153.770 90.508  1.00 57.59  ? 123 LYS C CE  1 
ATOM   5081 N NZ  . LYS C 1 49  ? 110.319 153.680 90.046  1.00 56.33  ? 123 LYS C NZ  1 
ATOM   5082 N N   . GLU C 1 50  ? 105.014 148.168 90.368  1.00 36.83  ? 124 GLU C N   1 
ATOM   5083 C CA  . GLU C 1 50  ? 104.267 147.104 89.703  1.00 34.35  ? 124 GLU C CA  1 
ATOM   5084 C C   . GLU C 1 50  ? 103.102 146.632 90.565  1.00 45.92  ? 124 GLU C C   1 
ATOM   5085 O O   . GLU C 1 50  ? 101.967 146.503 90.087  1.00 52.85  ? 124 GLU C O   1 
ATOM   5086 C CB  . GLU C 1 50  ? 105.199 145.939 89.373  1.00 42.29  ? 124 GLU C CB  1 
ATOM   5087 C CG  . GLU C 1 50  ? 104.891 145.245 88.058  1.00 47.77  ? 124 GLU C CG  1 
ATOM   5088 C CD  . GLU C 1 50  ? 105.896 144.161 87.723  1.00 52.12  ? 124 GLU C CD  1 
ATOM   5089 O OE1 . GLU C 1 50  ? 107.112 144.416 87.845  1.00 52.87  ? 124 GLU C OE1 1 
ATOM   5090 O OE2 . GLU C 1 50  ? 105.469 143.051 87.339  1.00 52.51  ? 124 GLU C OE2 1 
ATOM   5091 N N   . LEU C 1 51  ? 103.364 146.387 91.851  1.00 48.93  ? 125 LEU C N   1 
ATOM   5092 C CA  . LEU C 1 51  ? 102.316 145.928 92.755  1.00 44.64  ? 125 LEU C CA  1 
ATOM   5093 C C   . LEU C 1 51  ? 101.234 146.983 92.929  1.00 40.54  ? 125 LEU C C   1 
ATOM   5094 O O   . LEU C 1 51  ? 100.045 146.656 92.968  1.00 46.77  ? 125 LEU C O   1 
ATOM   5095 C CB  . LEU C 1 51  ? 102.918 145.551 94.107  1.00 45.99  ? 125 LEU C CB  1 
ATOM   5096 C CG  . LEU C 1 51  ? 101.930 145.051 95.161  1.00 43.83  ? 125 LEU C CG  1 
ATOM   5097 C CD1 . LEU C 1 51  ? 101.629 143.575 94.962  1.00 42.84  ? 125 LEU C CD1 1 
ATOM   5098 C CD2 . LEU C 1 51  ? 102.462 145.312 96.559  1.00 47.35  ? 125 LEU C CD2 1 
ATOM   5099 N N   . CYS C 1 52  ? 101.624 148.254 93.044  1.00 44.84  ? 126 CYS C N   1 
ATOM   5100 C CA  . CYS C 1 52  ? 100.633 149.309 93.223  1.00 47.06  ? 126 CYS C CA  1 
ATOM   5101 C C   . CYS C 1 52  ? 99.757  149.463 91.986  1.00 52.30  ? 126 CYS C C   1 
ATOM   5102 O O   . CYS C 1 52  ? 98.538  149.634 92.102  1.00 56.89  ? 126 CYS C O   1 
ATOM   5103 C CB  . CYS C 1 52  ? 101.329 150.624 93.566  1.00 50.63  ? 126 CYS C CB  1 
ATOM   5104 S SG  . CYS C 1 52  ? 101.693 150.818 95.325  1.00 62.65  ? 126 CYS C SG  1 
ATOM   5105 N N   . THR C 1 53  ? 100.355 149.404 90.793  1.00 46.60  ? 127 THR C N   1 
ATOM   5106 C CA  . THR C 1 53  ? 99.562  149.481 89.571  1.00 39.21  ? 127 THR C CA  1 
ATOM   5107 C C   . THR C 1 53  ? 98.622  148.291 89.447  1.00 39.73  ? 127 THR C C   1 
ATOM   5108 O O   . THR C 1 53  ? 97.472  148.445 89.019  1.00 48.30  ? 127 THR C O   1 
ATOM   5109 C CB  . THR C 1 53  ? 100.470 149.576 88.343  1.00 44.49  ? 127 THR C CB  1 
ATOM   5110 O OG1 . THR C 1 53  ? 101.348 148.444 88.299  1.00 50.61  ? 127 THR C OG1 1 
ATOM   5111 C CG2 . THR C 1 53  ? 101.280 150.864 88.368  1.00 50.19  ? 127 THR C CG2 1 
ATOM   5112 N N   . HIS C 1 54  ? 99.090  147.093 89.806  1.00 42.22  ? 128 HIS C N   1 
ATOM   5113 C CA  . HIS C 1 54  ? 98.213  145.929 89.732  1.00 40.63  ? 128 HIS C CA  1 
ATOM   5114 C C   . HIS C 1 54  ? 97.074  146.015 90.742  1.00 43.15  ? 128 HIS C C   1 
ATOM   5115 O O   . HIS C 1 54  ? 95.932  145.671 90.423  1.00 47.48  ? 128 HIS C O   1 
ATOM   5116 C CB  . HIS C 1 54  ? 99.005  144.642 89.940  1.00 37.72  ? 128 HIS C CB  1 
ATOM   5117 C CG  . HIS C 1 54  ? 98.155  143.411 89.909  1.00 39.60  ? 128 HIS C CG  1 
ATOM   5118 N ND1 . HIS C 1 54  ? 97.625  142.903 88.743  1.00 46.33  ? 128 HIS C ND1 1 
ATOM   5119 C CD2 . HIS C 1 54  ? 97.733  142.593 90.901  1.00 45.54  ? 128 HIS C CD2 1 
ATOM   5120 C CE1 . HIS C 1 54  ? 96.914  141.824 89.018  1.00 46.10  ? 128 HIS C CE1 1 
ATOM   5121 N NE2 . HIS C 1 54  ? 96.966  141.613 90.320  1.00 44.46  ? 128 HIS C NE2 1 
ATOM   5122 N N   . LEU C 1 55  ? 97.360  146.463 91.966  1.00 50.26  ? 129 LEU C N   1 
ATOM   5123 C CA  . LEU C 1 55  ? 96.334  146.491 93.002  1.00 44.66  ? 129 LEU C CA  1 
ATOM   5124 C C   . LEU C 1 55  ? 95.231  147.499 92.704  1.00 47.80  ? 129 LEU C C   1 
ATOM   5125 O O   . LEU C 1 55  ? 94.142  147.393 93.279  1.00 56.12  ? 129 LEU C O   1 
ATOM   5126 C CB  . LEU C 1 55  ? 96.960  146.797 94.364  1.00 43.90  ? 129 LEU C CB  1 
ATOM   5127 C CG  . LEU C 1 55  ? 97.853  145.721 94.990  1.00 45.92  ? 129 LEU C CG  1 
ATOM   5128 C CD1 . LEU C 1 55  ? 98.311  146.147 96.375  1.00 48.79  ? 129 LEU C CD1 1 
ATOM   5129 C CD2 . LEU C 1 55  ? 97.168  144.366 95.029  1.00 49.22  ? 129 LEU C CD2 1 
ATOM   5130 N N   . MET C 1 56  ? 95.485  148.473 91.829  1.00 52.07  ? 130 MET C N   1 
ATOM   5131 C CA  . MET C 1 56  ? 94.500  149.488 91.479  1.00 51.13  ? 130 MET C CA  1 
ATOM   5132 C C   . MET C 1 56  ? 93.908  149.286 90.087  1.00 49.82  ? 130 MET C C   1 
ATOM   5133 O O   . MET C 1 56  ? 93.380  150.236 89.501  1.00 58.46  ? 130 MET C O   1 
ATOM   5134 C CB  . MET C 1 56  ? 95.104  150.887 91.610  1.00 48.22  ? 130 MET C CB  1 
ATOM   5135 C CG  . MET C 1 56  ? 95.440  151.270 93.044  1.00 51.93  ? 130 MET C CG  1 
ATOM   5136 S SD  . MET C 1 56  ? 96.097  152.939 93.227  1.00 62.19  ? 130 MET C SD  1 
ATOM   5137 C CE  . MET C 1 56  ? 97.751  152.727 92.581  1.00 55.84  ? 130 MET C CE  1 
ATOM   5138 N N   . GLU C 1 57  ? 93.980  148.071 89.543  1.00 49.65  ? 131 GLU C N   1 
ATOM   5139 C CA  . GLU C 1 57  ? 93.224  147.725 88.348  1.00 49.87  ? 131 GLU C CA  1 
ATOM   5140 C C   . GLU C 1 57  ? 92.046  146.810 88.653  1.00 54.45  ? 131 GLU C C   1 
ATOM   5141 O O   . GLU C 1 57  ? 91.285  146.476 87.738  1.00 61.31  ? 131 GLU C O   1 
ATOM   5142 C CB  . GLU C 1 57  ? 94.128  147.082 87.289  1.00 50.26  ? 131 GLU C CB  1 
ATOM   5143 C CG  . GLU C 1 57  ? 94.656  145.706 87.638  1.00 54.18  ? 131 GLU C CG  1 
ATOM   5144 C CD  . GLU C 1 57  ? 95.596  145.163 86.579  1.00 59.80  ? 131 GLU C CD  1 
ATOM   5145 O OE1 . GLU C 1 57  ? 95.842  145.874 85.582  1.00 62.62  ? 131 GLU C OE1 1 
ATOM   5146 O OE2 . GLU C 1 57  ? 96.088  144.026 86.741  1.00 59.03  ? 131 GLU C OE2 1 
ATOM   5147 N N   . GLU C 1 58  ? 91.879  146.393 89.909  1.00 47.11  ? 132 GLU C N   1 
ATOM   5148 C CA  . GLU C 1 58  ? 90.644  145.778 90.377  1.00 50.97  ? 132 GLU C CA  1 
ATOM   5149 C C   . GLU C 1 58  ? 89.800  146.745 91.197  1.00 51.19  ? 132 GLU C C   1 
ATOM   5150 O O   . GLU C 1 58  ? 88.951  146.305 91.980  1.00 51.83  ? 132 GLU C O   1 
ATOM   5151 C CB  . GLU C 1 58  ? 90.932  144.517 91.196  1.00 49.87  ? 132 GLU C CB  1 
ATOM   5152 C CG  . GLU C 1 58  ? 91.526  143.366 90.405  1.00 50.84  ? 132 GLU C CG  1 
ATOM   5153 C CD  . GLU C 1 58  ? 93.019  143.492 90.230  1.00 53.43  ? 132 GLU C CD  1 
ATOM   5154 O OE1 . GLU C 1 58  ? 93.596  144.448 90.783  1.00 54.22  ? 132 GLU C OE1 1 
ATOM   5155 O OE2 . GLU C 1 58  ? 93.613  142.641 89.537  1.00 53.91  ? 132 GLU C OE2 1 
ATOM   5156 N N   . ASN C 1 59  ? 90.021  148.049 91.032  1.00 56.68  ? 133 ASN C N   1 
ATOM   5157 C CA  . ASN C 1 59  ? 89.263  149.087 91.729  1.00 58.55  ? 133 ASN C CA  1 
ATOM   5158 C C   . ASN C 1 59  ? 89.308  148.882 93.243  1.00 59.99  ? 133 ASN C C   1 
ATOM   5159 O O   . ASN C 1 59  ? 88.304  149.012 93.947  1.00 62.28  ? 133 ASN C O   1 
ATOM   5160 C CB  . ASN C 1 59  ? 87.821  149.139 91.221  1.00 58.81  ? 133 ASN C CB  1 
ATOM   5161 C CG  . ASN C 1 59  ? 87.227  150.533 91.290  1.00 61.99  ? 133 ASN C CG  1 
ATOM   5162 O OD1 . ASN C 1 59  ? 87.594  151.335 92.148  1.00 61.03  ? 133 ASN C OD1 1 
ATOM   5163 N ND2 . ASN C 1 59  ? 86.304  150.828 90.381  1.00 62.20  ? 133 ASN C ND2 1 
ATOM   5164 N N   . MET C 1 60  ? 90.496  148.557 93.745  1.00 51.19  ? 134 MET C N   1 
ATOM   5165 C CA  . MET C 1 60  ? 90.710  148.269 95.157  1.00 48.03  ? 134 MET C CA  1 
ATOM   5166 C C   . MET C 1 60  ? 91.589  149.347 95.776  1.00 41.66  ? 134 MET C C   1 
ATOM   5167 O O   . MET C 1 60  ? 92.684  149.626 95.277  1.00 48.30  ? 134 MET C O   1 
ATOM   5168 C CB  . MET C 1 60  ? 91.336  146.884 95.334  1.00 47.03  ? 134 MET C CB  1 
ATOM   5169 C CG  . MET C 1 60  ? 91.550  146.468 96.774  1.00 48.12  ? 134 MET C CG  1 
ATOM   5170 S SD  . MET C 1 60  ? 92.257  144.819 96.892  1.00 53.99  ? 134 MET C SD  1 
ATOM   5171 C CE  . MET C 1 60  ? 93.918  145.145 96.323  1.00 51.40  ? 134 MET C CE  1 
ATOM   5172 N N   . ILE C 1 61  ? 91.105  149.942 96.867  1.00 37.44  ? 135 ILE C N   1 
ATOM   5173 C CA  . ILE C 1 61  ? 91.779  151.081 97.481  1.00 35.98  ? 135 ILE C CA  1 
ATOM   5174 C C   . ILE C 1 61  ? 93.079  150.622 98.128  1.00 41.60  ? 135 ILE C C   1 
ATOM   5175 O O   . ILE C 1 61  ? 93.124  149.586 98.805  1.00 53.01  ? 135 ILE C O   1 
ATOM   5176 C CB  . ILE C 1 61  ? 90.853  151.758 98.503  1.00 37.37  ? 135 ILE C CB  1 
ATOM   5177 C CG1 . ILE C 1 61  ? 89.596  152.284 97.809  1.00 43.48  ? 135 ILE C CG1 1 
ATOM   5178 C CG2 . ILE C 1 61  ? 91.567  152.901 99.202  1.00 39.09  ? 135 ILE C CG2 1 
ATOM   5179 C CD1 . ILE C 1 61  ? 88.515  152.729 98.765  1.00 46.41  ? 135 ILE C CD1 1 
ATOM   5180 N N   . VAL C 1 62  ? 94.147  151.390 97.918  1.00 27.13  ? 136 VAL C N   1 
ATOM   5181 C CA  . VAL C 1 62  ? 95.461  151.074 98.462  1.00 27.46  ? 136 VAL C CA  1 
ATOM   5182 C C   . VAL C 1 62  ? 95.920  152.215 99.360  1.00 35.28  ? 136 VAL C C   1 
ATOM   5183 O O   . VAL C 1 62  ? 95.558  153.379 99.158  1.00 42.01  ? 136 VAL C O   1 
ATOM   5184 C CB  . VAL C 1 62  ? 96.493  150.798 97.347  1.00 26.80  ? 136 VAL C CB  1 
ATOM   5185 C CG1 . VAL C 1 62  ? 95.972  149.743 96.390  1.00 38.46  ? 136 VAL C CG1 1 
ATOM   5186 C CG2 . VAL C 1 62  ? 96.805  152.064 96.593  1.00 37.47  ? 136 VAL C CG2 1 
ATOM   5187 N N   . TYR C 1 63  ? 96.709  151.868 100.376 1.00 41.25  ? 137 TYR C N   1 
ATOM   5188 C CA  . TYR C 1 63  ? 97.228  152.821 101.348 1.00 35.55  ? 137 TYR C CA  1 
ATOM   5189 C C   . TYR C 1 63  ? 98.750  152.776 101.358 1.00 41.61  ? 137 TYR C C   1 
ATOM   5190 O O   . TYR C 1 63  ? 99.348  151.696 101.317 1.00 49.39  ? 137 TYR C O   1 
ATOM   5191 C CB  . TYR C 1 63  ? 96.700  152.527 102.756 1.00 40.23  ? 137 TYR C CB  1 
ATOM   5192 C CG  . TYR C 1 63  ? 95.288  153.002 103.014 1.00 39.31  ? 137 TYR C CG  1 
ATOM   5193 C CD1 . TYR C 1 63  ? 94.231  152.567 102.228 1.00 40.43  ? 137 TYR C CD1 1 
ATOM   5194 C CD2 . TYR C 1 63  ? 95.011  153.870 104.061 1.00 43.60  ? 137 TYR C CD2 1 
ATOM   5195 C CE1 . TYR C 1 63  ? 92.941  152.994 102.468 1.00 41.17  ? 137 TYR C CE1 1 
ATOM   5196 C CE2 . TYR C 1 63  ? 93.724  154.299 104.311 1.00 41.33  ? 137 TYR C CE2 1 
ATOM   5197 C CZ  . TYR C 1 63  ? 92.694  153.859 103.510 1.00 40.17  ? 137 TYR C CZ  1 
ATOM   5198 O OH  . TYR C 1 63  ? 91.411  154.288 103.756 1.00 42.89  ? 137 TYR C OH  1 
ATOM   5199 N N   . VAL C 1 64  ? 99.372  153.951 101.413 1.00 45.81  ? 138 VAL C N   1 
ATOM   5200 C CA  . VAL C 1 64  ? 100.825 154.076 101.437 1.00 45.56  ? 138 VAL C CA  1 
ATOM   5201 C C   . VAL C 1 64  ? 101.203 155.166 102.433 1.00 53.18  ? 138 VAL C C   1 
ATOM   5202 O O   . VAL C 1 64  ? 100.545 156.209 102.505 1.00 58.65  ? 138 VAL C O   1 
ATOM   5203 C CB  . VAL C 1 64  ? 101.391 154.386 100.032 1.00 51.30  ? 138 VAL C CB  1 
ATOM   5204 C CG1 . VAL C 1 64  ? 102.838 154.833 100.116 1.00 53.94  ? 138 VAL C CG1 1 
ATOM   5205 C CG2 . VAL C 1 64  ? 101.267 153.172 99.123  1.00 52.54  ? 138 VAL C CG2 1 
ATOM   5206 N N   . GLU C 1 65  ? 102.259 154.917 103.207 1.00 66.25  ? 139 GLU C N   1 
ATOM   5207 C CA  . GLU C 1 65  ? 102.755 155.909 104.154 1.00 69.83  ? 139 GLU C CA  1 
ATOM   5208 C C   . GLU C 1 65  ? 103.218 157.165 103.422 1.00 75.11  ? 139 GLU C C   1 
ATOM   5209 O O   . GLU C 1 65  ? 103.752 157.096 102.311 1.00 75.62  ? 139 GLU C O   1 
ATOM   5210 C CB  . GLU C 1 65  ? 103.898 155.311 104.982 1.00 70.87  ? 139 GLU C CB  1 
ATOM   5211 C CG  . GLU C 1 65  ? 104.944 156.305 105.473 1.00 73.18  ? 139 GLU C CG  1 
ATOM   5212 C CD  . GLU C 1 65  ? 104.455 157.153 106.633 1.00 74.84  ? 139 GLU C CD  1 
ATOM   5213 O OE1 . GLU C 1 65  ? 103.394 156.829 107.207 1.00 75.85  ? 139 GLU C OE1 1 
ATOM   5214 O OE2 . GLU C 1 65  ? 105.133 158.145 106.973 1.00 73.33  ? 139 GLU C OE2 1 
ATOM   5215 N N   . LYS C 1 66  ? 103.001 158.324 104.055 1.00 75.57  ? 140 LYS C N   1 
ATOM   5216 C CA  . LYS C 1 66  ? 103.297 159.601 103.409 1.00 70.68  ? 140 LYS C CA  1 
ATOM   5217 C C   . LYS C 1 66  ? 104.778 159.735 103.076 1.00 71.06  ? 140 LYS C C   1 
ATOM   5218 O O   . LYS C 1 66  ? 105.137 160.276 102.023 1.00 74.41  ? 140 LYS C O   1 
ATOM   5219 C CB  . LYS C 1 66  ? 102.847 160.757 104.301 1.00 71.16  ? 140 LYS C CB  1 
ATOM   5220 C CG  . LYS C 1 66  ? 103.058 162.131 103.683 1.00 76.26  ? 140 LYS C CG  1 
ATOM   5221 C CD  . LYS C 1 66  ? 102.490 163.232 104.563 1.00 78.20  ? 140 LYS C CD  1 
ATOM   5222 C CE  . LYS C 1 66  ? 102.832 164.609 104.016 1.00 75.94  ? 140 LYS C CE  1 
ATOM   5223 N NZ  . LYS C 1 66  ? 102.171 164.865 102.707 1.00 73.87  ? 140 LYS C NZ  1 
ATOM   5224 N N   . LYS C 1 67  ? 105.654 159.258 103.964 1.00 72.56  ? 141 LYS C N   1 
ATOM   5225 C CA  . LYS C 1 67  ? 107.090 159.393 103.735 1.00 73.81  ? 141 LYS C CA  1 
ATOM   5226 C C   . LYS C 1 67  ? 107.535 158.665 102.473 1.00 73.88  ? 141 LYS C C   1 
ATOM   5227 O O   . LYS C 1 67  ? 108.558 159.024 101.879 1.00 75.10  ? 141 LYS C O   1 
ATOM   5228 C CB  . LYS C 1 67  ? 107.865 158.878 104.947 1.00 74.26  ? 141 LYS C CB  1 
ATOM   5229 C CG  . LYS C 1 67  ? 108.209 159.953 105.966 1.00 74.83  ? 141 LYS C CG  1 
ATOM   5230 C CD  . LYS C 1 67  ? 108.294 159.380 107.371 1.00 75.16  ? 141 LYS C CD  1 
ATOM   5231 C CE  . LYS C 1 67  ? 108.085 160.460 108.420 1.00 75.12  ? 141 LYS C CE  1 
ATOM   5232 N NZ  . LYS C 1 67  ? 107.567 159.901 109.699 1.00 76.09  ? 141 LYS C NZ  1 
ATOM   5233 N N   . VAL C 1 68  ? 106.792 157.640 102.052 1.00 70.70  ? 142 VAL C N   1 
ATOM   5234 C CA  . VAL C 1 68  ? 107.135 156.930 100.824 1.00 72.34  ? 142 VAL C CA  1 
ATOM   5235 C C   . VAL C 1 68  ? 106.861 157.803 99.604  1.00 74.64  ? 142 VAL C C   1 
ATOM   5236 O O   . VAL C 1 68  ? 107.636 157.808 98.640  1.00 75.08  ? 142 VAL C O   1 
ATOM   5237 C CB  . VAL C 1 68  ? 106.373 155.595 100.752 1.00 73.42  ? 142 VAL C CB  1 
ATOM   5238 C CG1 . VAL C 1 68  ? 106.717 154.851 99.470  1.00 71.11  ? 142 VAL C CG1 1 
ATOM   5239 C CG2 . VAL C 1 68  ? 106.685 154.740 101.970 1.00 73.37  ? 142 VAL C CG2 1 
ATOM   5240 N N   . LEU C 1 69  ? 105.759 158.557 99.626  1.00 72.49  ? 143 LEU C N   1 
ATOM   5241 C CA  . LEU C 1 69  ? 105.368 159.350 98.466  1.00 71.22  ? 143 LEU C CA  1 
ATOM   5242 C C   . LEU C 1 69  ? 106.258 160.567 98.253  1.00 72.39  ? 143 LEU C C   1 
ATOM   5243 O O   . LEU C 1 69  ? 106.336 161.070 97.127  1.00 72.70  ? 143 LEU C O   1 
ATOM   5244 C CB  . LEU C 1 69  ? 103.912 159.794 98.602  1.00 69.09  ? 143 LEU C CB  1 
ATOM   5245 C CG  . LEU C 1 69  ? 102.916 158.658 98.818  1.00 69.44  ? 143 LEU C CG  1 
ATOM   5246 C CD1 . LEU C 1 69  ? 101.489 159.178 98.773  1.00 70.53  ? 143 LEU C CD1 1 
ATOM   5247 C CD2 . LEU C 1 69  ? 103.135 157.573 97.780  1.00 69.56  ? 143 LEU C CD2 1 
ATOM   5248 N N   . GLU C 1 70  ? 106.924 161.052 99.297  1.00 71.57  ? 144 GLU C N   1 
ATOM   5249 C CA  . GLU C 1 70  ? 107.798 162.211 99.189  1.00 68.90  ? 144 GLU C CA  1 
ATOM   5250 C C   . GLU C 1 70  ? 109.219 161.838 98.791  1.00 69.86  ? 144 GLU C C   1 
ATOM   5251 O O   . GLU C 1 70  ? 110.088 162.715 98.743  1.00 70.81  ? 144 GLU C O   1 
ATOM   5252 C CB  . GLU C 1 70  ? 107.809 162.988 100.509 1.00 71.91  ? 144 GLU C CB  1 
ATOM   5253 C CG  . GLU C 1 70  ? 108.442 162.243 101.671 1.00 74.24  ? 144 GLU C CG  1 
ATOM   5254 C CD  . GLU C 1 70  ? 108.383 163.026 102.970 1.00 76.77  ? 144 GLU C CD  1 
ATOM   5255 O OE1 . GLU C 1 70  ? 107.823 164.142 102.968 1.00 76.18  ? 144 GLU C OE1 1 
ATOM   5256 O OE2 . GLU C 1 70  ? 108.894 162.524 103.993 1.00 76.11  ? 144 GLU C OE2 1 
ATOM   5257 N N   . ASP C 1 71  ? 109.470 160.567 98.506  1.00 71.48  ? 145 ASP C N   1 
ATOM   5258 C CA  . ASP C 1 71  ? 110.805 160.128 98.125  1.00 72.33  ? 145 ASP C CA  1 
ATOM   5259 C C   . ASP C 1 71  ? 111.156 160.754 96.778  1.00 73.27  ? 145 ASP C C   1 
ATOM   5260 O O   . ASP C 1 71  ? 110.336 160.722 95.854  1.00 72.69  ? 145 ASP C O   1 
ATOM   5261 C CB  . ASP C 1 71  ? 110.836 158.591 98.076  1.00 73.85  ? 145 ASP C CB  1 
ATOM   5262 C CG  . ASP C 1 71  ? 112.138 158.008 97.511  1.00 75.63  ? 145 ASP C CG  1 
ATOM   5263 O OD1 . ASP C 1 71  ? 112.803 158.606 96.643  1.00 76.72  ? 145 ASP C OD1 1 
ATOM   5264 O OD2 . ASP C 1 71  ? 112.501 156.900 97.957  1.00 74.72  ? 145 ASP C OD2 1 
ATOM   5265 N N   . PRO C 1 72  ? 112.337 161.362 96.638  1.00 76.96  ? 146 PRO C N   1 
ATOM   5266 C CA  . PRO C 1 72  ? 112.707 161.946 95.337  1.00 75.95  ? 146 PRO C CA  1 
ATOM   5267 C C   . PRO C 1 72  ? 112.679 160.951 94.188  1.00 74.56  ? 146 PRO C C   1 
ATOM   5268 O O   . PRO C 1 72  ? 112.331 161.332 93.064  1.00 75.83  ? 146 PRO C O   1 
ATOM   5269 C CB  . PRO C 1 72  ? 114.129 162.477 95.574  1.00 75.74  ? 146 PRO C CB  1 
ATOM   5270 C CG  . PRO C 1 72  ? 114.307 162.555 97.049  1.00 75.60  ? 146 PRO C CG  1 
ATOM   5271 C CD  . PRO C 1 72  ? 113.213 161.802 97.737  1.00 77.51  ? 146 PRO C CD  1 
ATOM   5272 N N   . ALA C 1 73  ? 113.026 159.686 94.433  1.00 70.64  ? 147 ALA C N   1 
ATOM   5273 C CA  . ALA C 1 73  ? 113.105 158.713 93.350  1.00 71.85  ? 147 ALA C CA  1 
ATOM   5274 C C   . ALA C 1 73  ? 111.736 158.281 92.839  1.00 71.88  ? 147 ALA C C   1 
ATOM   5275 O O   . ALA C 1 73  ? 111.657 157.657 91.776  1.00 71.73  ? 147 ALA C O   1 
ATOM   5276 C CB  . ALA C 1 73  ? 113.899 157.487 93.802  1.00 70.42  ? 147 ALA C CB  1 
ATOM   5277 N N   . ILE C 1 74  ? 110.661 158.593 93.563  1.00 72.03  ? 148 ILE C N   1 
ATOM   5278 C CA  . ILE C 1 74  ? 109.322 158.218 93.125  1.00 71.45  ? 148 ILE C CA  1 
ATOM   5279 C C   . ILE C 1 74  ? 108.554 159.405 92.548  1.00 71.77  ? 148 ILE C C   1 
ATOM   5280 O O   . ILE C 1 74  ? 107.601 159.197 91.781  1.00 73.02  ? 148 ILE C O   1 
ATOM   5281 C CB  . ILE C 1 74  ? 108.527 157.566 94.279  1.00 72.84  ? 148 ILE C CB  1 
ATOM   5282 C CG1 . ILE C 1 74  ? 107.307 156.813 93.746  1.00 71.51  ? 148 ILE C CG1 1 
ATOM   5283 C CG2 . ILE C 1 74  ? 108.088 158.606 95.293  1.00 73.28  ? 148 ILE C CG2 1 
ATOM   5284 C CD1 . ILE C 1 74  ? 106.678 155.880 94.758  1.00 71.88  ? 148 ILE C CD1 1 
ATOM   5285 N N   . ALA C 1 75  ? 108.947 160.637 92.877  1.00 74.99  ? 149 ALA C N   1 
ATOM   5286 C CA  . ALA C 1 75  ? 108.317 161.812 92.283  1.00 75.78  ? 149 ALA C CA  1 
ATOM   5287 C C   . ALA C 1 75  ? 108.923 162.157 90.927  1.00 75.73  ? 149 ALA C C   1 
ATOM   5288 O O   . ALA C 1 75  ? 108.273 162.829 90.117  1.00 73.54  ? 149 ALA C O   1 
ATOM   5289 C CB  . ALA C 1 75  ? 108.425 163.000 93.227  1.00 74.00  ? 149 ALA C CB  1 
ATOM   5290 N N   . SER C 1 76  ? 110.147 161.701 90.650  1.00 80.17  ? 150 SER C N   1 
ATOM   5291 C CA  . SER C 1 76  ? 110.825 162.064 89.411  1.00 79.53  ? 150 SER C CA  1 
ATOM   5292 C C   . SER C 1 76  ? 110.233 161.372 88.190  1.00 79.22  ? 150 SER C C   1 
ATOM   5293 O O   . SER C 1 76  ? 110.457 161.834 87.066  1.00 80.67  ? 150 SER C O   1 
ATOM   5294 C CB  . SER C 1 76  ? 112.315 161.737 89.514  1.00 80.22  ? 150 SER C CB  1 
ATOM   5295 O OG  . SER C 1 76  ? 112.925 161.727 88.235  1.00 82.87  ? 150 SER C OG  1 
ATOM   5296 N N   . ASP C 1 77  ? 109.488 160.287 88.376  1.00 77.79  ? 151 ASP C N   1 
ATOM   5297 C CA  . ASP C 1 77  ? 108.917 159.530 87.270  1.00 80.27  ? 151 ASP C CA  1 
ATOM   5298 C C   . ASP C 1 77  ? 107.462 159.939 87.083  1.00 80.26  ? 151 ASP C C   1 
ATOM   5299 O O   . ASP C 1 77  ? 106.645 159.777 87.995  1.00 79.58  ? 151 ASP C O   1 
ATOM   5300 C CB  . ASP C 1 77  ? 109.026 158.026 87.525  1.00 80.35  ? 151 ASP C CB  1 
ATOM   5301 C CG  . ASP C 1 77  ? 108.243 157.206 86.518  1.00 81.62  ? 151 ASP C CG  1 
ATOM   5302 O OD1 . ASP C 1 77  ? 108.236 157.574 85.325  1.00 79.56  ? 151 ASP C OD1 1 
ATOM   5303 O OD2 . ASP C 1 77  ? 107.634 156.192 86.921  1.00 81.69  ? 151 ASP C OD2 1 
ATOM   5304 N N   . GLU C 1 78  ? 107.143 160.469 85.900  1.00 81.74  ? 152 GLU C N   1 
ATOM   5305 C CA  . GLU C 1 78  ? 105.776 160.874 85.604  1.00 79.90  ? 152 GLU C CA  1 
ATOM   5306 C C   . GLU C 1 78  ? 104.914 159.721 85.110  1.00 79.52  ? 152 GLU C C   1 
ATOM   5307 O O   . GLU C 1 78  ? 103.685 159.849 85.092  1.00 81.26  ? 152 GLU C O   1 
ATOM   5308 C CB  . GLU C 1 78  ? 105.773 162.001 84.567  1.00 80.19  ? 152 GLU C CB  1 
ATOM   5309 C CG  . GLU C 1 78  ? 105.808 161.527 83.121  1.00 82.16  ? 152 GLU C CG  1 
ATOM   5310 C CD  . GLU C 1 78  ? 107.120 160.860 82.753  1.00 84.81  ? 152 GLU C CD  1 
ATOM   5311 O OE1 . GLU C 1 78  ? 108.156 161.203 83.362  1.00 85.28  ? 152 GLU C OE1 1 
ATOM   5312 O OE2 . GLU C 1 78  ? 107.116 159.993 81.854  1.00 84.31  ? 152 GLU C OE2 1 
ATOM   5313 N N   . SER C 1 79  ? 105.525 158.604 84.707  1.00 69.86  ? 153 SER C N   1 
ATOM   5314 C CA  . SER C 1 79  ? 104.741 157.445 84.291  1.00 72.38  ? 153 SER C CA  1 
ATOM   5315 C C   . SER C 1 79  ? 103.971 156.851 85.463  1.00 73.29  ? 153 SER C C   1 
ATOM   5316 O O   . SER C 1 79  ? 102.795 156.494 85.326  1.00 72.08  ? 153 SER C O   1 
ATOM   5317 C CB  . SER C 1 79  ? 105.652 156.395 83.656  1.00 72.59  ? 153 SER C CB  1 
ATOM   5318 O OG  . SER C 1 79  ? 104.916 155.246 83.274  1.00 74.03  ? 153 SER C OG  1 
ATOM   5319 N N   . PHE C 1 80  ? 104.618 156.737 86.624  1.00 69.15  ? 154 PHE C N   1 
ATOM   5320 C CA  . PHE C 1 80  ? 103.953 156.230 87.816  1.00 68.44  ? 154 PHE C CA  1 
ATOM   5321 C C   . PHE C 1 80  ? 103.066 157.275 88.478  1.00 68.75  ? 154 PHE C C   1 
ATOM   5322 O O   . PHE C 1 80  ? 102.182 156.911 89.262  1.00 72.34  ? 154 PHE C O   1 
ATOM   5323 C CB  . PHE C 1 80  ? 104.992 155.723 88.819  1.00 67.26  ? 154 PHE C CB  1 
ATOM   5324 C CG  . PHE C 1 80  ? 104.401 155.001 89.996  1.00 64.88  ? 154 PHE C CG  1 
ATOM   5325 C CD1 . PHE C 1 80  ? 103.547 153.929 89.810  1.00 64.97  ? 154 PHE C CD1 1 
ATOM   5326 C CD2 . PHE C 1 80  ? 104.701 155.396 91.288  1.00 65.23  ? 154 PHE C CD2 1 
ATOM   5327 C CE1 . PHE C 1 80  ? 103.002 153.263 90.891  1.00 67.61  ? 154 PHE C CE1 1 
ATOM   5328 C CE2 . PHE C 1 80  ? 104.159 154.735 92.373  1.00 67.58  ? 154 PHE C CE2 1 
ATOM   5329 C CZ  . PHE C 1 80  ? 103.309 153.667 92.174  1.00 68.17  ? 154 PHE C CZ  1 
ATOM   5330 N N   . GLY C 1 81  ? 103.275 158.559 88.178  1.00 62.87  ? 155 GLY C N   1 
ATOM   5331 C CA  . GLY C 1 81  ? 102.490 159.609 88.801  1.00 62.76  ? 155 GLY C CA  1 
ATOM   5332 C C   . GLY C 1 81  ? 101.034 159.624 88.390  1.00 63.82  ? 155 GLY C C   1 
ATOM   5333 O O   . GLY C 1 81  ? 100.195 160.124 89.145  1.00 65.23  ? 155 GLY C O   1 
ATOM   5334 N N   . ALA C 1 82  ? 100.716 159.094 87.206  1.00 60.17  ? 156 ALA C N   1 
ATOM   5335 C CA  . ALA C 1 82  ? 99.325  159.054 86.767  1.00 62.24  ? 156 ALA C CA  1 
ATOM   5336 C C   . ALA C 1 82  ? 98.486  158.170 87.679  1.00 59.97  ? 156 ALA C C   1 
ATOM   5337 O O   . ALA C 1 82  ? 97.348  158.515 88.019  1.00 59.26  ? 156 ALA C O   1 
ATOM   5338 C CB  . ALA C 1 82  ? 99.244  158.565 85.321  1.00 61.82  ? 156 ALA C CB  1 
ATOM   5339 N N   . VAL C 1 83  ? 99.033  157.022 88.088  1.00 62.37  ? 157 VAL C N   1 
ATOM   5340 C CA  . VAL C 1 83  ? 98.328  156.120 88.994  1.00 63.75  ? 157 VAL C CA  1 
ATOM   5341 C C   . VAL C 1 83  ? 98.681  156.391 90.450  1.00 61.37  ? 157 VAL C C   1 
ATOM   5342 O O   . VAL C 1 83  ? 98.015  155.860 91.353  1.00 62.90  ? 157 VAL C O   1 
ATOM   5343 C CB  . VAL C 1 83  ? 98.634  154.655 88.615  1.00 62.25  ? 157 VAL C CB  1 
ATOM   5344 C CG1 . VAL C 1 83  ? 100.051 154.279 89.026  1.00 59.89  ? 157 VAL C CG1 1 
ATOM   5345 C CG2 . VAL C 1 83  ? 97.595  153.700 89.188  1.00 60.86  ? 157 VAL C CG2 1 
ATOM   5346 N N   . LYS C 1 84  ? 99.701  157.214 90.708  1.00 60.54  ? 158 LYS C N   1 
ATOM   5347 C CA  . LYS C 1 84  ? 100.071 157.556 92.077  1.00 59.21  ? 158 LYS C CA  1 
ATOM   5348 C C   . LYS C 1 84  ? 99.002  158.401 92.761  1.00 56.81  ? 158 LYS C C   1 
ATOM   5349 O O   . LYS C 1 84  ? 98.865  158.350 93.988  1.00 58.36  ? 158 LYS C O   1 
ATOM   5350 C CB  . LYS C 1 84  ? 101.409 158.297 92.079  1.00 60.28  ? 158 LYS C CB  1 
ATOM   5351 C CG  . LYS C 1 84  ? 101.959 158.617 93.456  1.00 60.25  ? 158 LYS C CG  1 
ATOM   5352 C CD  . LYS C 1 84  ? 103.324 159.277 93.360  1.00 58.01  ? 158 LYS C CD  1 
ATOM   5353 C CE  . LYS C 1 84  ? 103.873 159.606 94.738  1.00 63.05  ? 158 LYS C CE  1 
ATOM   5354 N NZ  . LYS C 1 84  ? 105.209 160.255 94.662  1.00 63.56  ? 158 LYS C NZ  1 
ATOM   5355 N N   . LYS C 1 85  ? 98.235  159.173 91.989  1.00 58.99  ? 159 LYS C N   1 
ATOM   5356 C CA  . LYS C 1 85  ? 97.261  160.096 92.559  1.00 58.35  ? 159 LYS C CA  1 
ATOM   5357 C C   . LYS C 1 85  ? 96.106  159.392 93.260  1.00 59.57  ? 159 LYS C C   1 
ATOM   5358 O O   . LYS C 1 85  ? 95.359  160.052 93.990  1.00 61.45  ? 159 LYS C O   1 
ATOM   5359 C CB  . LYS C 1 85  ? 96.712  161.015 91.467  1.00 59.06  ? 159 LYS C CB  1 
ATOM   5360 C CG  . LYS C 1 85  ? 95.738  162.068 91.971  1.00 60.02  ? 159 LYS C CG  1 
ATOM   5361 C CD  . LYS C 1 85  ? 95.271  162.975 90.846  1.00 60.29  ? 159 LYS C CD  1 
ATOM   5362 C CE  . LYS C 1 85  ? 94.278  164.011 91.345  1.00 61.61  ? 159 LYS C CE  1 
ATOM   5363 N NZ  . LYS C 1 85  ? 93.812  164.907 90.252  1.00 61.30  ? 159 LYS C NZ  1 
ATOM   5364 N N   . LYS C 1 86  ? 95.939  158.088 93.062  1.00 50.48  ? 160 LYS C N   1 
ATOM   5365 C CA  . LYS C 1 86  ? 94.868  157.341 93.707  1.00 51.95  ? 160 LYS C CA  1 
ATOM   5366 C C   . LYS C 1 86  ? 95.274  156.768 95.058  1.00 54.78  ? 160 LYS C C   1 
ATOM   5367 O O   . LYS C 1 86  ? 94.477  156.057 95.679  1.00 56.09  ? 160 LYS C O   1 
ATOM   5368 C CB  . LYS C 1 86  ? 94.382  156.215 92.789  1.00 53.99  ? 160 LYS C CB  1 
ATOM   5369 C CG  . LYS C 1 86  ? 93.692  156.707 91.527  1.00 54.46  ? 160 LYS C CG  1 
ATOM   5370 C CD  . LYS C 1 86  ? 93.086  155.560 90.735  1.00 54.82  ? 160 LYS C CD  1 
ATOM   5371 C CE  . LYS C 1 86  ? 94.155  154.746 90.027  1.00 51.94  ? 160 LYS C CE  1 
ATOM   5372 N NZ  . LYS C 1 86  ? 93.559  153.690 89.162  1.00 51.42  ? 160 LYS C NZ  1 
ATOM   5373 N N   . PHE C 1 87  ? 96.488  157.051 95.521  1.00 51.89  ? 161 PHE C N   1 
ATOM   5374 C CA  . PHE C 1 87  ? 96.928  156.587 96.827  1.00 44.87  ? 161 PHE C CA  1 
ATOM   5375 C C   . PHE C 1 87  ? 96.135  157.266 97.937  1.00 47.64  ? 161 PHE C C   1 
ATOM   5376 O O   . PHE C 1 87  ? 95.729  158.426 97.824  1.00 52.66  ? 161 PHE C O   1 
ATOM   5377 C CB  . PHE C 1 87  ? 98.417  156.872 97.021  1.00 46.91  ? 161 PHE C CB  1 
ATOM   5378 C CG  . PHE C 1 87  ? 99.322  155.933 96.277  1.00 45.43  ? 161 PHE C CG  1 
ATOM   5379 C CD1 . PHE C 1 87  ? 98.938  154.632 96.025  1.00 48.74  ? 161 PHE C CD1 1 
ATOM   5380 C CD2 . PHE C 1 87  ? 100.560 156.356 95.832  1.00 49.41  ? 161 PHE C CD2 1 
ATOM   5381 C CE1 . PHE C 1 87  ? 99.771  153.769 95.342  1.00 49.76  ? 161 PHE C CE1 1 
ATOM   5382 C CE2 . PHE C 1 87  ? 101.398 155.499 95.149  1.00 48.64  ? 161 PHE C CE2 1 
ATOM   5383 C CZ  . PHE C 1 87  ? 101.002 154.204 94.904  1.00 48.56  ? 161 PHE C CZ  1 
ATOM   5384 N N   . THR C 1 88  ? 95.912  156.528 99.020  1.00 51.32  ? 162 THR C N   1 
ATOM   5385 C CA  . THR C 1 88  ? 95.377  157.090 100.253 1.00 49.28  ? 162 THR C CA  1 
ATOM   5386 C C   . THR C 1 88  ? 96.537  157.248 101.228 1.00 54.03  ? 162 THR C C   1 
ATOM   5387 O O   . THR C 1 88  ? 97.238  156.276 101.527 1.00 59.31  ? 162 THR C O   1 
ATOM   5388 C CB  . THR C 1 88  ? 94.283  156.204 100.845 1.00 50.31  ? 162 THR C CB  1 
ATOM   5389 O OG1 . THR C 1 88  ? 93.295  155.932 99.845  1.00 54.41  ? 162 THR C OG1 1 
ATOM   5390 C CG2 . THR C 1 88  ? 93.618  156.910 102.013 1.00 53.68  ? 162 THR C CG2 1 
ATOM   5391 N N   . THR C 1 89  ? 96.735  158.466 101.719 1.00 66.52  ? 163 THR C N   1 
ATOM   5392 C CA  . THR C 1 89  ? 97.973  158.857 102.379 1.00 68.55  ? 163 THR C CA  1 
ATOM   5393 C C   . THR C 1 89  ? 97.758  159.018 103.878 1.00 71.30  ? 163 THR C C   1 
ATOM   5394 O O   . THR C 1 89  ? 96.785  159.646 104.308 1.00 74.10  ? 163 THR C O   1 
ATOM   5395 C CB  . THR C 1 89  ? 98.508  160.161 101.781 1.00 69.40  ? 163 THR C CB  1 
ATOM   5396 O OG1 . THR C 1 89  ? 98.747  159.981 100.380 1.00 68.75  ? 163 THR C OG1 1 
ATOM   5397 C CG2 . THR C 1 89  ? 99.802  160.570 102.457 1.00 68.33  ? 163 THR C CG2 1 
ATOM   5398 N N   . PHE C 1 90  ? 98.670  158.447 104.664 1.00 78.89  ? 164 PHE C N   1 
ATOM   5399 C CA  . PHE C 1 90  ? 98.724  158.653 106.103 1.00 79.80  ? 164 PHE C CA  1 
ATOM   5400 C C   . PHE C 1 90  ? 100.154 159.001 106.495 1.00 79.12  ? 164 PHE C C   1 
ATOM   5401 O O   . PHE C 1 90  ? 101.114 158.505 105.900 1.00 77.33  ? 164 PHE C O   1 
ATOM   5402 C CB  . PHE C 1 90  ? 98.231  157.414 106.871 1.00 74.43  ? 164 PHE C CB  1 
ATOM   5403 C CG  . PHE C 1 90  ? 99.175  156.245 106.823 1.00 74.66  ? 164 PHE C CG  1 
ATOM   5404 C CD1 . PHE C 1 90  ? 99.142  155.358 105.761 1.00 76.35  ? 164 PHE C CD1 1 
ATOM   5405 C CD2 . PHE C 1 90  ? 100.078 156.020 107.849 1.00 76.85  ? 164 PHE C CD2 1 
ATOM   5406 C CE1 . PHE C 1 90  ? 100.002 154.278 105.715 1.00 78.20  ? 164 PHE C CE1 1 
ATOM   5407 C CE2 . PHE C 1 90  ? 100.940 154.942 107.809 1.00 77.06  ? 164 PHE C CE2 1 
ATOM   5408 C CZ  . PHE C 1 90  ? 100.902 154.070 106.740 1.00 77.72  ? 164 PHE C CZ  1 
ATOM   5409 N N   . ARG C 1 91  ? 100.289 159.861 107.507 1.00 89.70  ? 165 ARG C N   1 
ATOM   5410 C CA  . ARG C 1 91  ? 101.580 160.439 107.866 1.00 91.28  ? 165 ARG C CA  1 
ATOM   5411 C C   . ARG C 1 91  ? 102.078 159.977 109.232 1.00 92.95  ? 165 ARG C C   1 
ATOM   5412 O O   . ARG C 1 91  ? 103.132 160.436 109.684 1.00 91.88  ? 165 ARG C O   1 
ATOM   5413 C CB  . ARG C 1 91  ? 101.496 161.966 107.839 1.00 91.19  ? 165 ARG C CB  1 
ATOM   5414 C CG  . ARG C 1 91  ? 102.803 162.665 108.177 1.00 91.62  ? 165 ARG C CG  1 
ATOM   5415 C CD  . ARG C 1 91  ? 102.739 164.181 108.081 1.00 92.08  ? 165 ARG C CD  1 
ATOM   5416 N NE  . ARG C 1 91  ? 104.022 164.804 108.392 1.00 94.09  ? 165 ARG C NE  1 
ATOM   5417 C CZ  . ARG C 1 91  ? 104.293 166.087 108.200 1.00 93.75  ? 165 ARG C CZ  1 
ATOM   5418 N NH1 . ARG C 1 91  ? 103.368 166.896 107.699 1.00 92.24  ? 165 ARG C NH1 1 
ATOM   5419 N NH2 . ARG C 1 91  ? 105.490 166.569 108.511 1.00 92.89  ? 165 ARG C NH2 1 
ATOM   5420 N N   . GLU C 1 92  ? 101.322 159.109 109.912 1.00 92.33  ? 166 GLU C N   1 
ATOM   5421 C CA  . GLU C 1 92  ? 101.716 158.517 111.190 1.00 93.45  ? 166 GLU C CA  1 
ATOM   5422 C C   . GLU C 1 92  ? 101.748 159.558 112.308 1.00 94.40  ? 166 GLU C C   1 
ATOM   5423 O O   . GLU C 1 92  ? 101.973 159.218 113.475 1.00 92.35  ? 166 GLU C O   1 
ATOM   5424 C CB  . GLU C 1 92  ? 103.076 157.816 111.060 1.00 92.61  ? 166 GLU C CB  1 
ATOM   5425 C CG  . GLU C 1 92  ? 103.435 156.874 112.203 1.00 92.14  ? 166 GLU C CG  1 
ATOM   5426 C CD  . GLU C 1 92  ? 104.723 156.115 111.949 1.00 93.19  ? 166 GLU C CD  1 
ATOM   5427 O OE1 . GLU C 1 92  ? 105.777 156.767 111.791 1.00 93.74  ? 166 GLU C OE1 1 
ATOM   5428 O OE2 . GLU C 1 92  ? 104.685 154.868 111.910 1.00 91.24  ? 166 GLU C OE2 1 
ATOM   5429 N N   . ASP C 1 93  ? 101.504 160.826 111.972 1.00 105.13 ? 167 ASP C N   1 
ATOM   5430 C CA  . ASP C 1 93  ? 101.505 161.873 112.989 1.00 105.34 ? 167 ASP C CA  1 
ATOM   5431 C C   . ASP C 1 93  ? 100.140 161.988 113.654 1.00 104.16 ? 167 ASP C C   1 
ATOM   5432 O O   . ASP C 1 93  ? 100.013 161.834 114.874 1.00 102.82 ? 167 ASP C O   1 
ATOM   5433 C CB  . ASP C 1 93  ? 101.918 163.207 112.367 1.00 104.67 ? 167 ASP C CB  1 
ATOM   5434 C CG  . ASP C 1 93  ? 101.814 164.362 113.343 1.00 104.60 ? 167 ASP C CG  1 
ATOM   5435 O OD1 . ASP C 1 93  ? 102.494 164.321 114.390 1.00 103.58 ? 167 ASP C OD1 1 
ATOM   5436 O OD2 . ASP C 1 93  ? 101.052 165.311 113.063 1.00 105.30 ? 167 ASP C OD2 1 
ATOM   5437 N N   . TYR C 1 94  ? 99.104  162.258 112.862 1.00 108.07 ? 168 TYR C N   1 
ATOM   5438 C CA  . TYR C 1 94  ? 97.740  162.315 113.369 1.00 108.67 ? 168 TYR C CA  1 
ATOM   5439 C C   . TYR C 1 94  ? 96.853  161.383 112.556 1.00 108.55 ? 168 TYR C C   1 
ATOM   5440 O O   . TYR C 1 94  ? 95.782  160.971 113.015 1.00 108.78 ? 168 TYR C O   1 
ATOM   5441 C CB  . TYR C 1 94  ? 97.199  163.744 113.324 1.00 108.11 ? 168 TYR C CB  1 
ATOM   5442 C CG  . TYR C 1 94  ? 95.751  163.866 113.747 1.00 109.46 ? 168 TYR C CG  1 
ATOM   5443 C CD1 . TYR C 1 94  ? 95.395  163.820 115.090 1.00 109.57 ? 168 TYR C CD1 1 
ATOM   5444 C CD2 . TYR C 1 94  ? 94.746  164.028 112.805 1.00 109.16 ? 168 TYR C CD2 1 
ATOM   5445 C CE1 . TYR C 1 94  ? 94.074  163.931 115.480 1.00 109.75 ? 168 TYR C CE1 1 
ATOM   5446 C CE2 . TYR C 1 94  ? 93.421  164.139 113.187 1.00 109.70 ? 168 TYR C CE2 1 
ATOM   5447 C CZ  . TYR C 1 94  ? 93.091  164.091 114.525 1.00 110.28 ? 168 TYR C CZ  1 
ATOM   5448 O OH  . TYR C 1 94  ? 91.775  164.199 114.911 1.00 110.61 ? 168 TYR C OH  1 
ATOM   5449 N N   . ASP C 1 95  ? 97.297  161.046 111.346 1.00 98.18  ? 169 ASP C N   1 
ATOM   5450 C CA  . ASP C 1 95  ? 96.571  160.117 110.491 1.00 97.41  ? 169 ASP C CA  1 
ATOM   5451 C C   . ASP C 1 95  ? 96.951  158.682 110.825 1.00 97.73  ? 169 ASP C C   1 
ATOM   5452 O O   . ASP C 1 95  ? 97.417  157.939 109.954 1.00 97.81  ? 169 ASP C O   1 
ATOM   5453 C CB  . ASP C 1 95  ? 96.852  160.412 109.016 1.00 96.90  ? 169 ASP C CB  1 
ATOM   5454 C CG  . ASP C 1 95  ? 96.255  161.728 108.560 1.00 97.01  ? 169 ASP C CG  1 
ATOM   5455 O OD1 . ASP C 1 95  ? 95.218  162.138 109.122 1.00 97.16  ? 169 ASP C OD1 1 
ATOM   5456 O OD2 . ASP C 1 95  ? 96.822  162.352 107.639 1.00 96.34  ? 169 ASP C OD2 1 
ATOM   5457 N N   . ASP C 1 96  ? 96.765  158.286 112.081 1.00 93.61  ? 170 ASP C N   1 
ATOM   5458 C CA  . ASP C 1 96  ? 97.099  156.930 112.494 1.00 92.34  ? 170 ASP C CA  1 
ATOM   5459 C C   . ASP C 1 96  ? 96.171  155.934 111.813 1.00 91.83  ? 170 ASP C C   1 
ATOM   5460 O O   . ASP C 1 96  ? 94.947  156.106 111.820 1.00 91.11  ? 170 ASP C O   1 
ATOM   5461 C CB  . ASP C 1 96  ? 97.002  156.802 114.014 1.00 90.85  ? 170 ASP C CB  1 
ATOM   5462 C CG  . ASP C 1 96  ? 95.621  157.142 114.542 1.00 91.76  ? 170 ASP C CG  1 
ATOM   5463 O OD1 . ASP C 1 96  ? 95.171  158.290 114.341 1.00 92.58  ? 170 ASP C OD1 1 
ATOM   5464 O OD2 . ASP C 1 96  ? 94.983  156.260 115.155 1.00 90.52  ? 170 ASP C OD2 1 
ATOM   5465 N N   . ILE C 1 97  ? 96.754  154.897 111.212 1.00 79.96  ? 171 ILE C N   1 
ATOM   5466 C CA  . ILE C 1 97  ? 95.947  153.868 110.573 1.00 78.54  ? 171 ILE C CA  1 
ATOM   5467 C C   . ILE C 1 97  ? 95.223  153.056 111.638 1.00 79.78  ? 171 ILE C C   1 
ATOM   5468 O O   . ILE C 1 97  ? 95.769  152.764 112.711 1.00 79.09  ? 171 ILE C O   1 
ATOM   5469 C CB  . ILE C 1 97  ? 96.813  152.987 109.657 1.00 76.27  ? 171 ILE C CB  1 
ATOM   5470 C CG1 . ILE C 1 97  ? 97.951  152.331 110.436 1.00 74.67  ? 171 ILE C CG1 1 
ATOM   5471 C CG2 . ILE C 1 97  ? 97.355  153.799 108.494 1.00 76.19  ? 171 ILE C CG2 1 
ATOM   5472 C CD1 . ILE C 1 97  ? 98.721  151.332 109.615 1.00 74.72  ? 171 ILE C CD1 1 
ATOM   5473 N N   . SER C 1 98  ? 93.982  152.695 111.340 1.00 77.42  ? 172 SER C N   1 
ATOM   5474 C CA  . SER C 1 98  ? 93.044  152.163 112.321 1.00 77.45  ? 172 SER C CA  1 
ATOM   5475 C C   . SER C 1 98  ? 92.272  151.041 111.639 1.00 74.69  ? 172 SER C C   1 
ATOM   5476 O O   . SER C 1 98  ? 92.712  150.481 110.629 1.00 75.32  ? 172 SER C O   1 
ATOM   5477 C CB  . SER C 1 98  ? 92.140  153.278 112.868 1.00 80.47  ? 172 SER C CB  1 
ATOM   5478 O OG  . SER C 1 98  ? 92.907  154.314 113.458 1.00 78.53  ? 172 SER C OG  1 
ATOM   5479 N N   . ASN C 1 99  ? 91.108  150.696 112.186 1.00 78.90  ? 173 ASN C N   1 
ATOM   5480 C CA  . ASN C 1 99  ? 90.308  149.629 111.601 1.00 80.93  ? 173 ASN C CA  1 
ATOM   5481 C C   . ASN C 1 99  ? 89.710  150.085 110.274 1.00 82.42  ? 173 ASN C C   1 
ATOM   5482 O O   . ASN C 1 99  ? 88.487  150.129 110.102 1.00 84.33  ? 173 ASN C O   1 
ATOM   5483 C CB  . ASN C 1 99  ? 89.214  149.183 112.578 1.00 81.09  ? 173 ASN C CB  1 
ATOM   5484 C CG  . ASN C 1 99  ? 88.334  150.332 113.046 1.00 81.59  ? 173 ASN C CG  1 
ATOM   5485 O OD1 . ASN C 1 99  ? 88.471  151.467 112.587 1.00 80.33  ? 173 ASN C OD1 1 
ATOM   5486 N ND2 . ASN C 1 99  ? 87.420  150.039 113.964 1.00 81.67  ? 173 ASN C ND2 1 
ATOM   5487 N N   . GLN C 1 100 ? 90.590  150.422 109.330 1.00 75.20  ? 174 GLN C N   1 
ATOM   5488 C CA  . GLN C 1 100 ? 90.227  150.777 107.970 1.00 71.70  ? 174 GLN C CA  1 
ATOM   5489 C C   . GLN C 1 100 ? 90.906  149.899 106.932 1.00 69.07  ? 174 GLN C C   1 
ATOM   5490 O O   . GLN C 1 100 ? 90.545  149.973 105.752 1.00 68.31  ? 174 GLN C O   1 
ATOM   5491 C CB  . GLN C 1 100 ? 90.583  152.246 107.686 1.00 67.85  ? 174 GLN C CB  1 
ATOM   5492 C CG  . GLN C 1 100 ? 89.785  153.255 108.494 1.00 70.95  ? 174 GLN C CG  1 
ATOM   5493 C CD  . GLN C 1 100 ? 90.216  154.684 108.224 1.00 73.37  ? 174 GLN C CD  1 
ATOM   5494 O OE1 . GLN C 1 100 ? 91.168  154.927 107.481 1.00 73.22  ? 174 GLN C OE1 1 
ATOM   5495 N NE2 . GLN C 1 100 ? 89.518  155.637 108.828 1.00 73.08  ? 174 GLN C NE2 1 
ATOM   5496 N N   . ILE C 1 101 ? 91.874  149.077 107.334 1.00 57.74  ? 175 ILE C N   1 
ATOM   5497 C CA  . ILE C 1 101 ? 92.635  148.222 106.432 1.00 48.65  ? 175 ILE C CA  1 
ATOM   5498 C C   . ILE C 1 101 ? 92.327  146.774 106.779 1.00 51.49  ? 175 ILE C C   1 
ATOM   5499 O O   . ILE C 1 101 ? 92.440  146.375 107.944 1.00 57.84  ? 175 ILE C O   1 
ATOM   5500 C CB  . ILE C 1 101 ? 94.146  148.486 106.540 1.00 46.78  ? 175 ILE C CB  1 
ATOM   5501 C CG1 . ILE C 1 101 ? 94.429  149.987 106.545 1.00 50.63  ? 175 ILE C CG1 1 
ATOM   5502 C CG2 . ILE C 1 101 ? 94.881  147.800 105.404 1.00 54.19  ? 175 ILE C CG2 1 
ATOM   5503 C CD1 . ILE C 1 101 ? 94.109  150.664 105.243 1.00 55.00  ? 175 ILE C CD1 1 
ATOM   5504 N N   . ASP C 1 102 ? 91.951  145.988 105.772 1.00 37.83  ? 176 ASP C N   1 
ATOM   5505 C CA  . ASP C 1 102 ? 91.632  144.582 105.975 1.00 45.97  ? 176 ASP C CA  1 
ATOM   5506 C C   . ASP C 1 102 ? 92.601  143.642 105.266 1.00 46.20  ? 176 ASP C C   1 
ATOM   5507 O O   . ASP C 1 102 ? 92.327  142.442 105.176 1.00 50.15  ? 176 ASP C O   1 
ATOM   5508 C CB  . ASP C 1 102 ? 90.192  144.299 105.537 1.00 50.96  ? 176 ASP C CB  1 
ATOM   5509 C CG  . ASP C 1 102 ? 89.962  144.549 104.056 1.00 51.29  ? 176 ASP C CG  1 
ATOM   5510 O OD1 . ASP C 1 102 ? 90.900  144.981 103.357 1.00 48.96  ? 176 ASP C OD1 1 
ATOM   5511 O OD2 . ASP C 1 102 ? 88.827  144.315 103.591 1.00 54.40  ? 176 ASP C OD2 1 
ATOM   5512 N N   . PHE C 1 103 ? 93.730  144.152 104.776 1.00 37.73  ? 177 PHE C N   1 
ATOM   5513 C CA  . PHE C 1 103 ? 94.706  143.324 104.079 1.00 32.56  ? 177 PHE C CA  1 
ATOM   5514 C C   . PHE C 1 103 ? 96.011  144.101 103.992 1.00 34.91  ? 177 PHE C C   1 
ATOM   5515 O O   . PHE C 1 103 ? 96.006  145.275 103.612 1.00 45.69  ? 177 PHE C O   1 
ATOM   5516 C CB  . PHE C 1 103 ? 94.198  142.941 102.682 1.00 41.03  ? 177 PHE C CB  1 
ATOM   5517 C CG  . PHE C 1 103 ? 95.146  142.079 101.900 1.00 29.21  ? 177 PHE C CG  1 
ATOM   5518 C CD1 . PHE C 1 103 ? 95.953  141.152 102.537 1.00 37.01  ? 177 PHE C CD1 1 
ATOM   5519 C CD2 . PHE C 1 103 ? 95.222  142.190 100.523 1.00 28.66  ? 177 PHE C CD2 1 
ATOM   5520 C CE1 . PHE C 1 103 ? 96.824  140.359 101.816 1.00 44.01  ? 177 PHE C CE1 1 
ATOM   5521 C CE2 . PHE C 1 103 ? 96.090  141.401 99.797  1.00 40.74  ? 177 PHE C CE2 1 
ATOM   5522 C CZ  . PHE C 1 103 ? 96.891  140.484 100.444 1.00 43.62  ? 177 PHE C CZ  1 
ATOM   5523 N N   . ILE C 1 104 ? 97.117  143.455 104.351 1.00 31.99  ? 178 ILE C N   1 
ATOM   5524 C CA  . ILE C 1 104 ? 98.429  144.090 104.395 1.00 24.80  ? 178 ILE C CA  1 
ATOM   5525 C C   . ILE C 1 104 ? 99.373  143.331 103.473 1.00 35.00  ? 178 ILE C C   1 
ATOM   5526 O O   . ILE C 1 104 ? 99.438  142.097 103.523 1.00 40.68  ? 178 ILE C O   1 
ATOM   5527 C CB  . ILE C 1 104 ? 98.991  144.126 105.828 1.00 29.05  ? 178 ILE C CB  1 
ATOM   5528 C CG1 . ILE C 1 104 ? 98.272  145.183 106.662 1.00 34.35  ? 178 ILE C CG1 1 
ATOM   5529 C CG2 . ILE C 1 104 ? 100.485 144.404 105.813 1.00 35.94  ? 178 ILE C CG2 1 
ATOM   5530 C CD1 . ILE C 1 104 ? 98.822  145.303 108.058 1.00 36.38  ? 178 ILE C CD1 1 
ATOM   5531 N N   . ILE C 1 105 ? 100.098 144.066 102.633 1.00 32.84  ? 179 ILE C N   1 
ATOM   5532 C CA  . ILE C 1 105 ? 101.175 143.517 101.819 1.00 27.25  ? 179 ILE C CA  1 
ATOM   5533 C C   . ILE C 1 105 ? 102.468 144.212 102.220 1.00 33.89  ? 179 ILE C C   1 
ATOM   5534 O O   . ILE C 1 105 ? 102.541 145.447 102.219 1.00 43.07  ? 179 ILE C O   1 
ATOM   5535 C CB  . ILE C 1 105 ? 100.903 143.687 100.314 1.00 26.76  ? 179 ILE C CB  1 
ATOM   5536 C CG1 . ILE C 1 105 ? 99.592  143.003 99.930  1.00 30.76  ? 179 ILE C CG1 1 
ATOM   5537 C CG2 . ILE C 1 105 ? 102.054 143.122 99.502  1.00 32.16  ? 179 ILE C CG2 1 
ATOM   5538 C CD1 . ILE C 1 105 ? 99.184  143.231 98.496  1.00 34.36  ? 179 ILE C CD1 1 
ATOM   5539 N N   . CYS C 1 106 ? 103.482 143.423 102.562 1.00 36.77  ? 180 CYS C N   1 
ATOM   5540 C CA  . CYS C 1 106 ? 104.751 143.934 103.059 1.00 32.40  ? 180 CYS C CA  1 
ATOM   5541 C C   . CYS C 1 106 ? 105.864 143.642 102.062 1.00 41.42  ? 180 CYS C C   1 
ATOM   5542 O O   . CYS C 1 106 ? 105.934 142.547 101.496 1.00 45.15  ? 180 CYS C O   1 
ATOM   5543 C CB  . CYS C 1 106 ? 105.095 143.318 104.417 1.00 36.55  ? 180 CYS C CB  1 
ATOM   5544 S SG  . CYS C 1 106 ? 104.286 144.113 105.822 1.00 55.29  ? 180 CYS C SG  1 
ATOM   5545 N N   . LEU C 1 107 ? 106.733 144.629 101.854 1.00 37.80  ? 181 LEU C N   1 
ATOM   5546 C CA  . LEU C 1 107 ? 107.856 144.518 100.934 1.00 29.63  ? 181 LEU C CA  1 
ATOM   5547 C C   . LEU C 1 107 ? 109.142 144.864 101.667 1.00 38.13  ? 181 LEU C C   1 
ATOM   5548 O O   . LEU C 1 107 ? 109.208 145.886 102.358 1.00 47.71  ? 181 LEU C O   1 
ATOM   5549 C CB  . LEU C 1 107 ? 107.680 145.452 99.731  1.00 31.63  ? 181 LEU C CB  1 
ATOM   5550 C CG  . LEU C 1 107 ? 106.535 145.183 98.755  1.00 32.64  ? 181 LEU C CG  1 
ATOM   5551 C CD1 . LEU C 1 107 ? 106.550 146.203 97.633  1.00 37.26  ? 181 LEU C CD1 1 
ATOM   5552 C CD2 . LEU C 1 107 ? 106.624 143.778 98.194  1.00 42.10  ? 181 LEU C CD2 1 
ATOM   5553 N N   . GLY C 1 108 ? 110.160 144.019 101.520 1.00 41.28  ? 182 GLY C N   1 
ATOM   5554 C CA  . GLY C 1 108 ? 111.487 144.377 101.983 1.00 47.53  ? 182 GLY C CA  1 
ATOM   5555 C C   . GLY C 1 108 ? 112.217 143.365 102.842 1.00 46.45  ? 182 GLY C C   1 
ATOM   5556 O O   . GLY C 1 108 ? 113.428 143.188 102.684 1.00 54.66  ? 182 GLY C O   1 
ATOM   5557 N N   . GLY C 1 109 ? 111.518 142.696 103.744 1.00 34.77  ? 183 GLY C N   1 
ATOM   5558 C CA  . GLY C 1 109 ? 112.163 141.728 104.604 1.00 42.57  ? 183 GLY C CA  1 
ATOM   5559 C C   . GLY C 1 109 ? 111.467 141.643 105.948 1.00 42.23  ? 183 GLY C C   1 
ATOM   5560 O O   . GLY C 1 109 ? 110.316 142.042 106.093 1.00 49.62  ? 183 GLY C O   1 
ATOM   5561 N N   . ASP C 1 110 ? 112.206 141.105 106.921 1.00 36.04  ? 184 ASP C N   1 
ATOM   5562 C CA  . ASP C 1 110 ? 111.635 140.819 108.234 1.00 35.64  ? 184 ASP C CA  1 
ATOM   5563 C C   . ASP C 1 110 ? 111.248 142.099 108.964 1.00 38.26  ? 184 ASP C C   1 
ATOM   5564 O O   . ASP C 1 110 ? 110.133 142.214 109.488 1.00 42.15  ? 184 ASP C O   1 
ATOM   5565 C CB  . ASP C 1 110 ? 112.631 140.010 109.064 1.00 40.98  ? 184 ASP C CB  1 
ATOM   5566 C CG  . ASP C 1 110 ? 112.601 138.533 108.732 1.00 45.08  ? 184 ASP C CG  1 
ATOM   5567 O OD1 . ASP C 1 110 ? 111.498 137.956 108.690 1.00 43.28  ? 184 ASP C OD1 1 
ATOM   5568 O OD2 . ASP C 1 110 ? 113.681 137.949 108.509 1.00 50.61  ? 184 ASP C OD2 1 
ATOM   5569 N N   . GLY C 1 111 ? 112.154 143.079 108.998 1.00 42.39  ? 185 GLY C N   1 
ATOM   5570 C CA  . GLY C 1 111 ? 111.912 144.301 109.746 1.00 37.53  ? 185 GLY C CA  1 
ATOM   5571 C C   . GLY C 1 111 ? 110.705 145.082 109.279 1.00 37.95  ? 185 GLY C C   1 
ATOM   5572 O O   . GLY C 1 111 ? 110.150 145.870 110.051 1.00 38.42  ? 185 GLY C O   1 
ATOM   5573 N N   . THR C 1 112 ? 110.289 144.888 108.027 1.00 37.46  ? 186 THR C N   1 
ATOM   5574 C CA  . THR C 1 112 ? 109.051 145.498 107.557 1.00 32.52  ? 186 THR C CA  1 
ATOM   5575 C C   . THR C 1 112 ? 107.856 144.960 108.333 1.00 38.04  ? 186 THR C C   1 
ATOM   5576 O O   . THR C 1 112 ? 107.022 145.730 108.825 1.00 48.29  ? 186 THR C O   1 
ATOM   5577 C CB  . THR C 1 112 ? 108.882 145.244 106.059 1.00 38.67  ? 186 THR C CB  1 
ATOM   5578 O OG1 . THR C 1 112 ? 110.130 145.469 105.391 1.00 44.09  ? 186 THR C OG1 1 
ATOM   5579 C CG2 . THR C 1 112 ? 107.834 146.167 105.477 1.00 41.62  ? 186 THR C CG2 1 
ATOM   5580 N N   . LEU C 1 113 ? 107.782 143.635 108.486 1.00 39.62  ? 187 LEU C N   1 
ATOM   5581 C CA  . LEU C 1 113 ? 106.653 143.030 109.185 1.00 37.85  ? 187 LEU C CA  1 
ATOM   5582 C C   . LEU C 1 113 ? 106.575 143.521 110.623 1.00 39.25  ? 187 LEU C C   1 
ATOM   5583 O O   . LEU C 1 113 ? 105.484 143.807 111.132 1.00 45.34  ? 187 LEU C O   1 
ATOM   5584 C CB  . LEU C 1 113 ? 106.764 141.508 109.143 1.00 33.29  ? 187 LEU C CB  1 
ATOM   5585 C CG  . LEU C 1 113 ? 105.530 140.757 109.636 1.00 38.51  ? 187 LEU C CG  1 
ATOM   5586 C CD1 . LEU C 1 113 ? 104.370 141.011 108.697 1.00 43.38  ? 187 LEU C CD1 1 
ATOM   5587 C CD2 . LEU C 1 113 ? 105.808 139.270 109.754 1.00 41.16  ? 187 LEU C CD2 1 
ATOM   5588 N N   . LEU C 1 114 ? 107.727 143.633 111.288 1.00 39.66  ? 188 LEU C N   1 
ATOM   5589 C CA  . LEU C 1 114 ? 107.762 144.212 112.626 1.00 38.40  ? 188 LEU C CA  1 
ATOM   5590 C C   . LEU C 1 114 ? 107.140 145.600 112.631 1.00 35.71  ? 188 LEU C C   1 
ATOM   5591 O O   . LEU C 1 114 ? 106.325 145.921 113.504 1.00 42.80  ? 188 LEU C O   1 
ATOM   5592 C CB  . LEU C 1 114 ? 109.204 144.270 113.128 1.00 36.81  ? 188 LEU C CB  1 
ATOM   5593 C CG  . LEU C 1 114 ? 109.690 143.103 113.987 1.00 35.41  ? 188 LEU C CG  1 
ATOM   5594 C CD1 . LEU C 1 114 ? 109.537 141.794 113.234 1.00 41.35  ? 188 LEU C CD1 1 
ATOM   5595 C CD2 . LEU C 1 114 ? 111.136 143.319 114.396 1.00 35.24  ? 188 LEU C CD2 1 
ATOM   5596 N N   . TYR C 1 115 ? 107.493 146.427 111.643 1.00 34.97  ? 189 TYR C N   1 
ATOM   5597 C CA  . TYR C 1 115 ? 106.893 147.751 111.538 1.00 31.53  ? 189 TYR C CA  1 
ATOM   5598 C C   . TYR C 1 115 ? 105.383 147.647 111.374 1.00 35.01  ? 189 TYR C C   1 
ATOM   5599 O O   . TYR C 1 115 ? 104.632 148.458 111.929 1.00 40.82  ? 189 TYR C O   1 
ATOM   5600 C CB  . TYR C 1 115 ? 107.521 148.513 110.371 1.00 34.99  ? 189 TYR C CB  1 
ATOM   5601 C CG  . TYR C 1 115 ? 106.976 149.907 110.163 1.00 34.12  ? 189 TYR C CG  1 
ATOM   5602 C CD1 . TYR C 1 115 ? 107.112 150.879 111.145 1.00 40.48  ? 189 TYR C CD1 1 
ATOM   5603 C CD2 . TYR C 1 115 ? 106.341 150.256 108.980 1.00 38.67  ? 189 TYR C CD2 1 
ATOM   5604 C CE1 . TYR C 1 115 ? 106.622 152.156 110.959 1.00 42.63  ? 189 TYR C CE1 1 
ATOM   5605 C CE2 . TYR C 1 115 ? 105.847 151.531 108.784 1.00 41.63  ? 189 TYR C CE2 1 
ATOM   5606 C CZ  . TYR C 1 115 ? 105.990 152.476 109.777 1.00 41.87  ? 189 TYR C CZ  1 
ATOM   5607 O OH  . TYR C 1 115 ? 105.500 153.747 109.586 1.00 45.78  ? 189 TYR C OH  1 
ATOM   5608 N N   . ALA C 1 116 ? 104.920 146.634 110.635 1.00 33.82  ? 190 ALA C N   1 
ATOM   5609 C CA  . ALA C 1 116 ? 103.485 146.418 110.491 1.00 31.48  ? 190 ALA C CA  1 
ATOM   5610 C C   . ALA C 1 116 ? 102.824 146.158 111.836 1.00 36.41  ? 190 ALA C C   1 
ATOM   5611 O O   . ALA C 1 116 ? 101.676 146.564 112.051 1.00 44.68  ? 190 ALA C O   1 
ATOM   5612 C CB  . ALA C 1 116 ? 103.220 145.257 109.533 1.00 37.36  ? 190 ALA C CB  1 
ATOM   5613 N N   . SER C 1 117 ? 103.525 145.486 112.752 1.00 31.49  ? 191 SER C N   1 
ATOM   5614 C CA  . SER C 1 117 ? 102.974 145.292 114.088 1.00 30.29  ? 191 SER C CA  1 
ATOM   5615 C C   . SER C 1 117 ? 103.036 146.575 114.905 1.00 38.92  ? 191 SER C C   1 
ATOM   5616 O O   . SER C 1 117 ? 102.217 146.771 115.810 1.00 42.44  ? 191 SER C O   1 
ATOM   5617 C CB  . SER C 1 117 ? 103.714 144.166 114.807 1.00 38.25  ? 191 SER C CB  1 
ATOM   5618 O OG  . SER C 1 117 ? 105.113 144.389 114.803 1.00 44.41  ? 191 SER C OG  1 
ATOM   5619 N N   . SER C 1 118 ? 103.994 147.454 114.605 1.00 38.31  ? 192 SER C N   1 
ATOM   5620 C CA  . SER C 1 118 ? 104.100 148.710 115.340 1.00 32.72  ? 192 SER C CA  1 
ATOM   5621 C C   . SER C 1 118 ? 102.946 149.645 115.005 1.00 38.17  ? 192 SER C C   1 
ATOM   5622 O O   . SER C 1 118 ? 102.481 150.402 115.865 1.00 43.56  ? 192 SER C O   1 
ATOM   5623 C CB  . SER C 1 118 ? 105.439 149.381 115.041 1.00 39.85  ? 192 SER C CB  1 
ATOM   5624 O OG  . SER C 1 118 ? 105.552 150.619 115.721 1.00 45.30  ? 192 SER C OG  1 
ATOM   5625 N N   . LEU C 1 119 ? 102.471 149.608 113.759 1.00 41.07  ? 193 LEU C N   1 
ATOM   5626 C CA  . LEU C 1 119 ? 101.416 150.521 113.337 1.00 39.66  ? 193 LEU C CA  1 
ATOM   5627 C C   . LEU C 1 119 ? 100.060 150.133 113.913 1.00 40.65  ? 193 LEU C C   1 
ATOM   5628 O O   . LEU C 1 119 ? 99.221  151.007 114.156 1.00 45.85  ? 193 LEU C O   1 
ATOM   5629 C CB  . LEU C 1 119 ? 101.351 150.568 111.813 1.00 38.56  ? 193 LEU C CB  1 
ATOM   5630 C CG  . LEU C 1 119 ? 102.429 151.386 111.104 1.00 39.09  ? 193 LEU C CG  1 
ATOM   5631 C CD1 . LEU C 1 119 ? 102.417 151.103 109.614 1.00 41.30  ? 193 LEU C CD1 1 
ATOM   5632 C CD2 . LEU C 1 119 ? 102.222 152.866 111.371 1.00 44.56  ? 193 LEU C CD2 1 
ATOM   5633 N N   . PHE C 1 120 ? 99.826  148.843 114.135 1.00 38.56  ? 194 PHE C N   1 
ATOM   5634 C CA  . PHE C 1 120 ? 98.567  148.345 114.677 1.00 38.09  ? 194 PHE C CA  1 
ATOM   5635 C C   . PHE C 1 120 ? 98.804  147.861 116.101 1.00 39.31  ? 194 PHE C C   1 
ATOM   5636 O O   . PHE C 1 120 ? 99.381  146.788 116.311 1.00 43.41  ? 194 PHE C O   1 
ATOM   5637 C CB  . PHE C 1 120 ? 98.000  147.226 113.808 1.00 36.35  ? 194 PHE C CB  1 
ATOM   5638 C CG  . PHE C 1 120 ? 97.569  147.674 112.444 1.00 36.67  ? 194 PHE C CG  1 
ATOM   5639 C CD1 . PHE C 1 120 ? 96.341  148.285 112.260 1.00 43.35  ? 194 PHE C CD1 1 
ATOM   5640 C CD2 . PHE C 1 120 ? 98.390  147.490 111.347 1.00 36.80  ? 194 PHE C CD2 1 
ATOM   5641 C CE1 . PHE C 1 120 ? 95.938  148.698 111.008 1.00 45.02  ? 194 PHE C CE1 1 
ATOM   5642 C CE2 . PHE C 1 120 ? 97.992  147.906 110.095 1.00 38.18  ? 194 PHE C CE2 1 
ATOM   5643 C CZ  . PHE C 1 120 ? 96.764  148.507 109.924 1.00 41.74  ? 194 PHE C CZ  1 
ATOM   5644 N N   . GLN C 1 121 ? 98.357  148.649 117.074 1.00 36.76  ? 195 GLN C N   1 
ATOM   5645 C CA  . GLN C 1 121 ? 98.468  148.291 118.480 1.00 40.49  ? 195 GLN C CA  1 
ATOM   5646 C C   . GLN C 1 121 ? 97.286  147.465 118.969 1.00 41.43  ? 195 GLN C C   1 
ATOM   5647 O O   . GLN C 1 121 ? 97.304  146.998 120.112 1.00 44.22  ? 195 GLN C O   1 
ATOM   5648 C CB  . GLN C 1 121 ? 98.610  149.555 119.333 1.00 38.97  ? 195 GLN C CB  1 
ATOM   5649 C CG  . GLN C 1 121 ? 99.878  150.346 119.048 1.00 42.53  ? 195 GLN C CG  1 
ATOM   5650 C CD  . GLN C 1 121 ? 101.137 149.596 119.439 1.00 43.12  ? 195 GLN C CD  1 
ATOM   5651 O OE1 . GLN C 1 121 ? 101.173 148.915 120.463 1.00 43.79  ? 195 GLN C OE1 1 
ATOM   5652 N NE2 . GLN C 1 121 ? 102.176 149.715 118.622 1.00 39.93  ? 195 GLN C NE2 1 
ATOM   5653 N N   . GLY C 1 122 ? 96.268  147.276 118.134 1.00 34.94  ? 196 GLY C N   1 
ATOM   5654 C CA  . GLY C 1 122 ? 95.138  146.436 118.476 1.00 28.95  ? 196 GLY C CA  1 
ATOM   5655 C C   . GLY C 1 122 ? 95.002  145.260 117.533 1.00 36.10  ? 196 GLY C C   1 
ATOM   5656 O O   . GLY C 1 122 ? 95.986  144.571 117.249 1.00 43.57  ? 196 GLY C O   1 
ATOM   5657 N N   . SER C 1 123 ? 93.790  145.018 117.041 1.00 33.52  ? 197 SER C N   1 
ATOM   5658 C CA  . SER C 1 123 ? 93.579  143.943 116.083 1.00 31.83  ? 197 SER C CA  1 
ATOM   5659 C C   . SER C 1 123 ? 94.259  144.278 114.761 1.00 35.77  ? 197 SER C C   1 
ATOM   5660 O O   . SER C 1 123 ? 94.210  145.417 114.290 1.00 45.28  ? 197 SER C O   1 
ATOM   5661 C CB  . SER C 1 123 ? 92.086  143.704 115.869 1.00 38.39  ? 197 SER C CB  1 
ATOM   5662 O OG  . SER C 1 123 ? 91.867  142.668 114.929 1.00 42.37  ? 197 SER C OG  1 
ATOM   5663 N N   . VAL C 1 124 ? 94.896  143.277 114.162 1.00 39.77  ? 198 VAL C N   1 
ATOM   5664 C CA  . VAL C 1 124 ? 95.738  143.457 112.987 1.00 37.14  ? 198 VAL C CA  1 
ATOM   5665 C C   . VAL C 1 124 ? 95.131  142.657 111.842 1.00 39.27  ? 198 VAL C C   1 
ATOM   5666 O O   . VAL C 1 124 ? 94.792  141.488 112.032 1.00 39.70  ? 198 VAL C O   1 
ATOM   5667 C CB  . VAL C 1 124 ? 97.191  143.014 113.231 1.00 31.89  ? 198 VAL C CB  1 
ATOM   5668 C CG1 . VAL C 1 124 ? 98.039  143.278 112.000 1.00 36.99  ? 198 VAL C CG1 1 
ATOM   5669 C CG2 . VAL C 1 124 ? 97.766  143.710 114.452 1.00 38.49  ? 198 VAL C CG2 1 
ATOM   5670 N N   . PRO C 1 125 ? 94.976  143.234 110.654 1.00 38.03  ? 199 PRO C N   1 
ATOM   5671 C CA  . PRO C 1 125 ? 94.506  142.460 109.502 1.00 35.75  ? 199 PRO C CA  1 
ATOM   5672 C C   . PRO C 1 125 ? 95.572  141.488 109.032 1.00 37.49  ? 199 PRO C C   1 
ATOM   5673 O O   . PRO C 1 125 ? 96.749  141.626 109.397 1.00 47.10  ? 199 PRO C O   1 
ATOM   5674 C CB  . PRO C 1 125 ? 94.229  143.542 108.447 1.00 36.48  ? 199 PRO C CB  1 
ATOM   5675 C CG  . PRO C 1 125 ? 95.140  144.656 108.824 1.00 33.70  ? 199 PRO C CG  1 
ATOM   5676 C CD  . PRO C 1 125 ? 95.150  144.658 110.323 1.00 36.48  ? 199 PRO C CD  1 
ATOM   5677 N N   . PRO C 1 126 ? 95.202  140.484 108.235 1.00 21.14  ? 200 PRO C N   1 
ATOM   5678 C CA  . PRO C 1 126 ? 96.206  139.536 107.735 1.00 29.25  ? 200 PRO C CA  1 
ATOM   5679 C C   . PRO C 1 126 ? 97.270  140.235 106.903 1.00 28.92  ? 200 PRO C C   1 
ATOM   5680 O O   . PRO C 1 126 ? 97.003  141.216 106.205 1.00 41.68  ? 200 PRO C O   1 
ATOM   5681 C CB  . PRO C 1 126 ? 95.388  138.553 106.888 1.00 33.50  ? 200 PRO C CB  1 
ATOM   5682 C CG  . PRO C 1 126 ? 94.057  139.188 106.688 1.00 36.06  ? 200 PRO C CG  1 
ATOM   5683 C CD  . PRO C 1 126 ? 93.836  140.119 107.828 1.00 28.76  ? 200 PRO C CD  1 
ATOM   5684 N N   . VAL C 1 127 ? 98.491  139.716 106.988 1.00 25.66  ? 201 VAL C N   1 
ATOM   5685 C CA  . VAL C 1 127 ? 99.660  140.333 106.377 1.00 25.28  ? 201 VAL C CA  1 
ATOM   5686 C C   . VAL C 1 127 ? 100.260 139.378 105.355 1.00 32.75  ? 201 VAL C C   1 
ATOM   5687 O O   . VAL C 1 127 ? 100.323 138.164 105.579 1.00 37.22  ? 201 VAL C O   1 
ATOM   5688 C CB  . VAL C 1 127 ? 100.708 140.733 107.438 1.00 27.06  ? 201 VAL C CB  1 
ATOM   5689 C CG1 . VAL C 1 127 ? 100.124 141.754 108.397 1.00 37.02  ? 201 VAL C CG1 1 
ATOM   5690 C CG2 . VAL C 1 127 ? 101.184 139.514 108.207 1.00 36.77  ? 201 VAL C CG2 1 
ATOM   5691 N N   . MET C 1 128 ? 100.672 139.931 104.218 1.00 37.41  ? 202 MET C N   1 
ATOM   5692 C CA  . MET C 1 128 ? 101.417 139.207 103.196 1.00 28.07  ? 202 MET C CA  1 
ATOM   5693 C C   . MET C 1 128 ? 102.831 139.767 103.154 1.00 36.38  ? 202 MET C C   1 
ATOM   5694 O O   . MET C 1 128 ? 103.021 140.958 102.885 1.00 49.03  ? 202 MET C O   1 
ATOM   5695 C CB  . MET C 1 128 ? 100.754 139.345 101.828 1.00 32.06  ? 202 MET C CB  1 
ATOM   5696 C CG  . MET C 1 128 ? 101.411 138.517 100.741 1.00 38.80  ? 202 MET C CG  1 
ATOM   5697 S SD  . MET C 1 128 ? 100.590 138.713 99.153  1.00 53.77  ? 202 MET C SD  1 
ATOM   5698 C CE  . MET C 1 128 ? 99.079  137.822 99.454  1.00 32.87  ? 202 MET C CE  1 
ATOM   5699 N N   . ALA C 1 129 ? 103.817 138.916 103.412 1.00 23.38  ? 203 ALA C N   1 
ATOM   5700 C CA  . ALA C 1 129 ? 105.212 139.328 103.432 1.00 23.60  ? 203 ALA C CA  1 
ATOM   5701 C C   . ALA C 1 129 ? 105.916 138.826 102.180 1.00 32.57  ? 203 ALA C C   1 
ATOM   5702 O O   . ALA C 1 129 ? 105.842 137.636 101.855 1.00 39.32  ? 203 ALA C O   1 
ATOM   5703 C CB  . ALA C 1 129 ? 105.915 138.807 104.686 1.00 32.98  ? 203 ALA C CB  1 
ATOM   5704 N N   . PHE C 1 130 ? 106.600 139.731 101.486 1.00 30.41  ? 204 PHE C N   1 
ATOM   5705 C CA  . PHE C 1 130 ? 107.338 139.414 100.272 1.00 19.81  ? 204 PHE C CA  1 
ATOM   5706 C C   . PHE C 1 130 ? 108.829 139.571 100.532 1.00 27.16  ? 204 PHE C C   1 
ATOM   5707 O O   . PHE C 1 130 ? 109.265 140.601 101.056 1.00 37.97  ? 204 PHE C O   1 
ATOM   5708 C CB  . PHE C 1 130 ? 106.921 140.326 99.117  1.00 27.22  ? 204 PHE C CB  1 
ATOM   5709 C CG  . PHE C 1 130 ? 105.697 139.866 98.384  1.00 23.55  ? 204 PHE C CG  1 
ATOM   5710 C CD1 . PHE C 1 130 ? 105.748 138.776 97.535  1.00 21.89  ? 204 PHE C CD1 1 
ATOM   5711 C CD2 . PHE C 1 130 ? 104.500 140.541 98.526  1.00 22.55  ? 204 PHE C CD2 1 
ATOM   5712 C CE1 . PHE C 1 130 ? 104.623 138.358 96.856  1.00 20.85  ? 204 PHE C CE1 1 
ATOM   5713 C CE2 . PHE C 1 130 ? 103.375 140.130 97.848  1.00 21.48  ? 204 PHE C CE2 1 
ATOM   5714 C CZ  . PHE C 1 130 ? 103.435 139.037 97.013  1.00 16.58  ? 204 PHE C CZ  1 
ATOM   5715 N N   . HIS C 1 131 ? 109.605 138.554 100.165 1.00 35.36  ? 205 HIS C N   1 
ATOM   5716 C CA  . HIS C 1 131 ? 111.062 138.611 100.252 1.00 30.03  ? 205 HIS C CA  1 
ATOM   5717 C C   . HIS C 1 131 ? 111.599 139.038 98.889  1.00 42.39  ? 205 HIS C C   1 
ATOM   5718 O O   . HIS C 1 131 ? 111.755 138.222 97.977  1.00 48.13  ? 205 HIS C O   1 
ATOM   5719 C CB  . HIS C 1 131 ? 111.637 137.275 100.720 1.00 32.95  ? 205 HIS C CB  1 
ATOM   5720 C CG  . HIS C 1 131 ? 111.350 136.127 99.803  1.00 33.61  ? 205 HIS C CG  1 
ATOM   5721 N ND1 . HIS C 1 131 ? 112.083 135.885 98.661  1.00 38.37  ? 205 HIS C ND1 1 
ATOM   5722 C CD2 . HIS C 1 131 ? 110.417 135.148 99.865  1.00 37.97  ? 205 HIS C CD2 1 
ATOM   5723 C CE1 . HIS C 1 131 ? 111.610 134.811 98.056  1.00 39.39  ? 205 HIS C CE1 1 
ATOM   5724 N NE2 . HIS C 1 131 ? 110.599 134.344 98.766  1.00 44.53  ? 205 HIS C NE2 1 
ATOM   5725 N N   . LEU C 1 132 ? 111.869 140.336 98.749  1.00 38.78  ? 206 LEU C N   1 
ATOM   5726 C CA  . LEU C 1 132 ? 112.387 140.897 97.502  1.00 34.53  ? 206 LEU C CA  1 
ATOM   5727 C C   . LEU C 1 132 ? 113.909 140.816 97.542  1.00 42.35  ? 206 LEU C C   1 
ATOM   5728 O O   . LEU C 1 132 ? 114.617 141.796 97.783  1.00 45.76  ? 206 LEU C O   1 
ATOM   5729 C CB  . LEU C 1 132 ? 111.895 142.324 97.314  1.00 37.41  ? 206 LEU C CB  1 
ATOM   5730 C CG  . LEU C 1 132 ? 110.654 142.522 96.447  1.00 38.42  ? 206 LEU C CG  1 
ATOM   5731 C CD1 . LEU C 1 132 ? 109.491 141.701 96.964  1.00 40.92  ? 206 LEU C CD1 1 
ATOM   5732 C CD2 . LEU C 1 132 ? 110.290 143.989 96.434  1.00 44.87  ? 206 LEU C CD2 1 
ATOM   5733 N N   . GLY C 1 133 ? 114.415 139.612 97.296  1.00 50.38  ? 207 GLY C N   1 
ATOM   5734 C CA  . GLY C 1 133 ? 115.830 139.349 97.439  1.00 50.67  ? 207 GLY C CA  1 
ATOM   5735 C C   . GLY C 1 133 ? 116.196 139.051 98.879  1.00 53.94  ? 207 GLY C C   1 
ATOM   5736 O O   . GLY C 1 133 ? 115.383 139.150 99.801  1.00 54.11  ? 207 GLY C O   1 
ATOM   5737 N N   . SER C 1 134 ? 117.458 138.679 99.067  1.00 63.23  ? 208 SER C N   1 
ATOM   5738 C CA  . SER C 1 134 ? 117.992 138.298 100.381 1.00 63.40  ? 208 SER C CA  1 
ATOM   5739 C C   . SER C 1 134 ? 117.154 137.132 100.917 1.00 62.54  ? 208 SER C C   1 
ATOM   5740 O O   . SER C 1 134 ? 116.574 136.360 100.141 1.00 63.01  ? 208 SER C O   1 
ATOM   5741 C CB  . SER C 1 134 ? 118.049 139.514 101.292 1.00 60.79  ? 208 SER C CB  1 
ATOM   5742 O OG  . SER C 1 134 ? 118.190 139.131 102.649 1.00 62.10  ? 208 SER C OG  1 
ATOM   5743 N N   . LEU C 1 135 ? 117.085 136.985 102.238 1.00 52.97  ? 209 LEU C N   1 
ATOM   5744 C CA  . LEU C 1 135 ? 116.314 135.921 102.862 1.00 50.21  ? 209 LEU C CA  1 
ATOM   5745 C C   . LEU C 1 135 ? 115.625 136.460 104.104 1.00 53.61  ? 209 LEU C C   1 
ATOM   5746 O O   . LEU C 1 135 ? 116.184 137.292 104.824 1.00 55.41  ? 209 LEU C O   1 
ATOM   5747 C CB  . LEU C 1 135 ? 117.201 134.725 103.236 1.00 54.14  ? 209 LEU C CB  1 
ATOM   5748 C CG  . LEU C 1 135 ? 117.807 133.919 102.086 1.00 55.71  ? 209 LEU C CG  1 
ATOM   5749 C CD1 . LEU C 1 135 ? 118.782 132.879 102.614 1.00 53.40  ? 209 LEU C CD1 1 
ATOM   5750 C CD2 . LEU C 1 135 ? 116.714 133.261 101.257 1.00 53.29  ? 209 LEU C CD2 1 
ATOM   5751 N N   . GLY C 1 136 ? 114.408 135.983 104.348 1.00 43.44  ? 210 GLY C N   1 
ATOM   5752 C CA  . GLY C 1 136 ? 113.659 136.389 105.519 1.00 34.53  ? 210 GLY C CA  1 
ATOM   5753 C C   . GLY C 1 136 ? 112.912 135.240 106.162 1.00 35.59  ? 210 GLY C C   1 
ATOM   5754 O O   . GLY C 1 136 ? 112.258 134.453 105.472 1.00 41.90  ? 210 GLY C O   1 
ATOM   5755 N N   . PHE C 1 137 ? 113.004 135.133 107.488 1.00 30.72  ? 211 PHE C N   1 
ATOM   5756 C CA  . PHE C 1 137 ? 112.313 134.060 108.193 1.00 30.58  ? 211 PHE C CA  1 
ATOM   5757 C C   . PHE C 1 137 ? 110.802 134.255 108.178 1.00 39.96  ? 211 PHE C C   1 
ATOM   5758 O O   . PHE C 1 137 ? 110.053 133.274 108.121 1.00 42.26  ? 211 PHE C O   1 
ATOM   5759 C CB  . PHE C 1 137 ? 112.826 133.968 109.630 1.00 32.65  ? 211 PHE C CB  1 
ATOM   5760 C CG  . PHE C 1 137 ? 112.759 132.586 110.211 1.00 28.96  ? 211 PHE C CG  1 
ATOM   5761 C CD1 . PHE C 1 137 ? 111.554 132.061 110.643 1.00 35.29  ? 211 PHE C CD1 1 
ATOM   5762 C CD2 . PHE C 1 137 ? 113.899 131.812 110.322 1.00 30.79  ? 211 PHE C CD2 1 
ATOM   5763 C CE1 . PHE C 1 137 ? 111.488 130.792 111.176 1.00 36.54  ? 211 PHE C CE1 1 
ATOM   5764 C CE2 . PHE C 1 137 ? 113.839 130.541 110.854 1.00 37.29  ? 211 PHE C CE2 1 
ATOM   5765 C CZ  . PHE C 1 137 ? 112.631 130.031 111.281 1.00 37.89  ? 211 PHE C CZ  1 
ATOM   5766 N N   . LEU C 1 138 ? 110.339 135.503 108.226 1.00 40.63  ? 212 LEU C N   1 
ATOM   5767 C CA  . LEU C 1 138 ? 108.917 135.814 108.284 1.00 33.78  ? 212 LEU C CA  1 
ATOM   5768 C C   . LEU C 1 138 ? 108.357 136.257 106.939 1.00 40.56  ? 212 LEU C C   1 
ATOM   5769 O O   . LEU C 1 138 ? 107.206 136.702 106.875 1.00 42.61  ? 212 LEU C O   1 
ATOM   5770 C CB  . LEU C 1 138 ? 108.652 136.892 109.342 1.00 35.80  ? 212 LEU C CB  1 
ATOM   5771 C CG  . LEU C 1 138 ? 108.644 136.559 110.842 1.00 33.99  ? 212 LEU C CG  1 
ATOM   5772 C CD1 . LEU C 1 138 ? 109.819 135.692 111.281 1.00 38.67  ? 212 LEU C CD1 1 
ATOM   5773 C CD2 . LEU C 1 138 ? 108.609 137.841 111.659 1.00 33.21  ? 212 LEU C CD2 1 
ATOM   5774 N N   . THR C 1 139 ? 109.140 136.147 105.863 1.00 42.08  ? 213 THR C N   1 
ATOM   5775 C CA  . THR C 1 139 ? 108.732 136.568 104.522 1.00 32.23  ? 213 THR C CA  1 
ATOM   5776 C C   . THR C 1 139 ? 108.752 135.356 103.599 1.00 31.85  ? 213 THR C C   1 
ATOM   5777 O O   . THR C 1 139 ? 109.796 135.027 103.013 1.00 42.34  ? 213 THR C O   1 
ATOM   5778 C CB  . THR C 1 139 ? 109.641 137.674 103.993 1.00 31.32  ? 213 THR C CB  1 
ATOM   5779 O OG1 . THR C 1 139 ? 110.971 137.165 103.835 1.00 39.53  ? 213 THR C OG1 1 
ATOM   5780 C CG2 . THR C 1 139 ? 109.665 138.847 104.956 1.00 35.49  ? 213 THR C CG2 1 
ATOM   5781 N N   . PRO C 1 140 ? 107.622 134.662 103.439 1.00 22.40  ? 214 PRO C N   1 
ATOM   5782 C CA  . PRO C 1 140 ? 107.611 133.418 102.662 1.00 25.08  ? 214 PRO C CA  1 
ATOM   5783 C C   . PRO C 1 140 ? 107.224 133.547 101.196 1.00 30.81  ? 214 PRO C C   1 
ATOM   5784 O O   . PRO C 1 140 ? 107.338 132.552 100.467 1.00 37.12  ? 214 PRO C O   1 
ATOM   5785 C CB  . PRO C 1 140 ? 106.567 132.584 103.412 1.00 25.85  ? 214 PRO C CB  1 
ATOM   5786 C CG  . PRO C 1 140 ? 105.574 133.603 103.865 1.00 25.28  ? 214 PRO C CG  1 
ATOM   5787 C CD  . PRO C 1 140 ? 106.350 134.873 104.150 1.00 25.30  ? 214 PRO C CD  1 
ATOM   5788 N N   . PHE C 1 141 ? 106.779 134.714 100.738 1.00 33.98  ? 215 PHE C N   1 
ATOM   5789 C CA  . PHE C 1 141 ? 106.239 134.868 99.392  1.00 26.69  ? 215 PHE C CA  1 
ATOM   5790 C C   . PHE C 1 141 ? 107.309 135.422 98.459  1.00 32.17  ? 215 PHE C C   1 
ATOM   5791 O O   . PHE C 1 141 ? 107.883 136.483 98.726  1.00 39.60  ? 215 PHE C O   1 
ATOM   5792 C CB  . PHE C 1 141 ? 105.017 135.784 99.398  1.00 25.16  ? 215 PHE C CB  1 
ATOM   5793 C CG  . PHE C 1 141 ? 103.735 135.084 99.742  1.00 26.14  ? 215 PHE C CG  1 
ATOM   5794 C CD1 . PHE C 1 141 ? 103.014 134.415 98.770  1.00 33.94  ? 215 PHE C CD1 1 
ATOM   5795 C CD2 . PHE C 1 141 ? 103.249 135.101 101.036 1.00 29.07  ? 215 PHE C CD2 1 
ATOM   5796 C CE1 . PHE C 1 141 ? 101.833 133.773 99.084  1.00 32.44  ? 215 PHE C CE1 1 
ATOM   5797 C CE2 . PHE C 1 141 ? 102.069 134.461 101.356 1.00 33.25  ? 215 PHE C CE2 1 
ATOM   5798 C CZ  . PHE C 1 141 ? 101.361 133.796 100.378 1.00 30.35  ? 215 PHE C CZ  1 
ATOM   5799 N N   . SER C 1 142 ? 107.569 134.705 97.369  1.00 32.17  ? 216 SER C N   1 
ATOM   5800 C CA  . SER C 1 142 ? 108.446 135.200 96.319  1.00 32.50  ? 216 SER C CA  1 
ATOM   5801 C C   . SER C 1 142 ? 107.676 136.142 95.404  1.00 38.84  ? 216 SER C C   1 
ATOM   5802 O O   . SER C 1 142 ? 106.504 135.909 95.096  1.00 44.42  ? 216 SER C O   1 
ATOM   5803 C CB  . SER C 1 142 ? 109.026 134.038 95.513  1.00 38.77  ? 216 SER C CB  1 
ATOM   5804 O OG  . SER C 1 142 ? 108.008 133.356 94.802  1.00 42.17  ? 216 SER C OG  1 
ATOM   5805 N N   . PHE C 1 143 ? 108.340 137.216 94.971  1.00 34.41  ? 217 PHE C N   1 
ATOM   5806 C CA  . PHE C 1 143 ? 107.652 138.225 94.176  1.00 33.30  ? 217 PHE C CA  1 
ATOM   5807 C C   . PHE C 1 143 ? 107.313 137.743 92.772  1.00 34.13  ? 217 PHE C C   1 
ATOM   5808 O O   . PHE C 1 143 ? 106.450 138.342 92.121  1.00 44.51  ? 217 PHE C O   1 
ATOM   5809 C CB  . PHE C 1 143 ? 108.485 139.503 94.089  1.00 35.92  ? 217 PHE C CB  1 
ATOM   5810 C CG  . PHE C 1 143 ? 107.694 140.701 93.653  1.00 32.88  ? 217 PHE C CG  1 
ATOM   5811 C CD1 . PHE C 1 143 ? 106.773 141.284 94.505  1.00 33.29  ? 217 PHE C CD1 1 
ATOM   5812 C CD2 . PHE C 1 143 ? 107.856 141.231 92.385  1.00 33.84  ? 217 PHE C CD2 1 
ATOM   5813 C CE1 . PHE C 1 143 ? 106.038 142.382 94.106  1.00 35.96  ? 217 PHE C CE1 1 
ATOM   5814 C CE2 . PHE C 1 143 ? 107.122 142.328 91.980  1.00 36.71  ? 217 PHE C CE2 1 
ATOM   5815 C CZ  . PHE C 1 143 ? 106.212 142.904 92.841  1.00 38.17  ? 217 PHE C CZ  1 
ATOM   5816 N N   . GLU C 1 144 ? 107.967 136.692 92.287  1.00 38.02  ? 218 GLU C N   1 
ATOM   5817 C CA  . GLU C 1 144 ? 107.648 136.171 90.966  1.00 36.37  ? 218 GLU C CA  1 
ATOM   5818 C C   . GLU C 1 144 ? 106.233 135.606 90.947  1.00 32.56  ? 218 GLU C C   1 
ATOM   5819 O O   . GLU C 1 144 ? 105.796 134.946 91.895  1.00 42.40  ? 218 GLU C O   1 
ATOM   5820 C CB  . GLU C 1 144 ? 108.660 135.100 90.554  1.00 42.41  ? 218 GLU C CB  1 
ATOM   5821 C CG  . GLU C 1 144 ? 108.664 133.855 91.428  1.00 43.70  ? 218 GLU C CG  1 
ATOM   5822 C CD  . GLU C 1 144 ? 109.730 132.857 91.020  1.00 46.30  ? 218 GLU C CD  1 
ATOM   5823 O OE1 . GLU C 1 144 ? 110.486 133.147 90.068  1.00 45.00  ? 218 GLU C OE1 1 
ATOM   5824 O OE2 . GLU C 1 144 ? 109.813 131.782 91.651  1.00 47.70  ? 218 GLU C OE2 1 
ATOM   5825 N N   . ASN C 1 145 ? 105.510 135.886 89.860  1.00 30.11  ? 219 ASN C N   1 
ATOM   5826 C CA  . ASN C 1 145 ? 104.126 135.438 89.690  1.00 32.12  ? 219 ASN C CA  1 
ATOM   5827 C C   . ASN C 1 145 ? 103.247 135.890 90.855  1.00 43.77  ? 219 ASN C C   1 
ATOM   5828 O O   . ASN C 1 145 ? 102.435 135.123 91.377  1.00 48.60  ? 219 ASN C O   1 
ATOM   5829 C CB  . ASN C 1 145 ? 104.054 133.920 89.512  1.00 32.17  ? 219 ASN C CB  1 
ATOM   5830 C CG  . ASN C 1 145 ? 103.004 133.501 88.504  1.00 38.59  ? 219 ASN C CG  1 
ATOM   5831 O OD1 . ASN C 1 145 ? 101.967 134.148 88.365  1.00 43.36  ? 219 ASN C OD1 1 
ATOM   5832 N ND2 . ASN C 1 145 ? 103.269 132.412 87.792  1.00 40.60  ? 219 ASN C ND2 1 
ATOM   5833 N N   . PHE C 1 146 ? 103.410 137.149 91.268  1.00 41.36  ? 220 PHE C N   1 
ATOM   5834 C CA  . PHE C 1 146 ? 102.668 137.649 92.419  1.00 29.20  ? 220 PHE C CA  1 
ATOM   5835 C C   . PHE C 1 146 ? 101.199 137.895 92.108  1.00 33.52  ? 220 PHE C C   1 
ATOM   5836 O O   . PHE C 1 146 ? 100.386 137.941 93.038  1.00 44.65  ? 220 PHE C O   1 
ATOM   5837 C CB  . PHE C 1 146 ? 103.315 138.931 92.952  1.00 31.66  ? 220 PHE C CB  1 
ATOM   5838 C CG  . PHE C 1 146 ? 103.103 140.137 92.079  1.00 35.48  ? 220 PHE C CG  1 
ATOM   5839 C CD1 . PHE C 1 146 ? 103.919 140.370 90.985  1.00 40.18  ? 220 PHE C CD1 1 
ATOM   5840 C CD2 . PHE C 1 146 ? 102.099 141.047 92.363  1.00 37.04  ? 220 PHE C CD2 1 
ATOM   5841 C CE1 . PHE C 1 146 ? 103.731 141.481 90.188  1.00 39.04  ? 220 PHE C CE1 1 
ATOM   5842 C CE2 . PHE C 1 146 ? 101.905 142.158 91.569  1.00 37.57  ? 220 PHE C CE2 1 
ATOM   5843 C CZ  . PHE C 1 146 ? 102.723 142.376 90.481  1.00 38.96  ? 220 PHE C CZ  1 
ATOM   5844 N N   . GLN C 1 147 ? 100.842 138.048 90.830  1.00 32.55  ? 221 GLN C N   1 
ATOM   5845 C CA  . GLN C 1 147 ? 99.448  138.299 90.474  1.00 35.15  ? 221 GLN C CA  1 
ATOM   5846 C C   . GLN C 1 147 ? 98.553  137.151 90.919  1.00 41.35  ? 221 GLN C C   1 
ATOM   5847 O O   . GLN C 1 147 ? 97.520  137.366 91.566  1.00 45.43  ? 221 GLN C O   1 
ATOM   5848 C CB  . GLN C 1 147 ? 99.322  138.517 88.966  1.00 36.90  ? 221 GLN C CB  1 
ATOM   5849 C CG  . GLN C 1 147 ? 99.661  139.917 88.487  1.00 37.70  ? 221 GLN C CG  1 
ATOM   5850 C CD  . GLN C 1 147 ? 101.082 140.035 87.980  1.00 38.08  ? 221 GLN C CD  1 
ATOM   5851 O OE1 . GLN C 1 147 ? 101.756 139.031 87.748  1.00 43.86  ? 221 GLN C OE1 1 
ATOM   5852 N NE2 . GLN C 1 147 ? 101.540 141.265 87.783  1.00 38.16  ? 221 GLN C NE2 1 
ATOM   5853 N N   . SER C 1 148 ? 98.941  135.918 90.588  1.00 36.10  ? 222 SER C N   1 
ATOM   5854 C CA  . SER C 1 148 ? 98.130  134.761 90.953  1.00 34.13  ? 222 SER C CA  1 
ATOM   5855 C C   . SER C 1 148 ? 98.036  134.610 92.465  1.00 43.46  ? 222 SER C C   1 
ATOM   5856 O O   . SER C 1 148 ? 96.971  134.279 92.998  1.00 48.23  ? 222 SER C O   1 
ATOM   5857 C CB  . SER C 1 148 ? 98.707  133.496 90.320  1.00 37.88  ? 222 SER C CB  1 
ATOM   5858 O OG  . SER C 1 148 ? 98.270  132.337 91.006  1.00 45.01  ? 222 SER C OG  1 
ATOM   5859 N N   . GLN C 1 149 ? 99.139  134.859 93.174  1.00 37.43  ? 223 GLN C N   1 
ATOM   5860 C CA  . GLN C 1 149 ? 99.141  134.706 94.625  1.00 30.12  ? 223 GLN C CA  1 
ATOM   5861 C C   . GLN C 1 149 ? 98.225  135.727 95.292  1.00 34.66  ? 223 GLN C C   1 
ATOM   5862 O O   . GLN C 1 149 ? 97.409  135.374 96.156  1.00 45.82  ? 223 GLN C O   1 
ATOM   5863 C CB  . GLN C 1 149 ? 100.569 134.826 95.154  1.00 31.01  ? 223 GLN C CB  1 
ATOM   5864 C CG  . GLN C 1 149 ? 101.527 133.811 94.551  1.00 27.68  ? 223 GLN C CG  1 
ATOM   5865 C CD  . GLN C 1 149 ? 102.903 133.857 95.177  1.00 29.70  ? 223 GLN C CD  1 
ATOM   5866 O OE1 . GLN C 1 149 ? 103.412 132.846 95.660  1.00 32.65  ? 223 GLN C OE1 1 
ATOM   5867 N NE2 . GLN C 1 149 ? 103.517 135.033 95.171  1.00 38.51  ? 223 GLN C NE2 1 
ATOM   5868 N N   . VAL C 1 150 ? 98.336  136.999 94.899  1.00 29.65  ? 224 VAL C N   1 
ATOM   5869 C CA  . VAL C 1 150 ? 97.481  138.016 95.502  1.00 29.16  ? 224 VAL C CA  1 
ATOM   5870 C C   . VAL C 1 150 ? 96.024  137.777 95.127  1.00 37.69  ? 224 VAL C C   1 
ATOM   5871 O O   . VAL C 1 150 ? 95.122  138.003 95.940  1.00 47.36  ? 224 VAL C O   1 
ATOM   5872 C CB  . VAL C 1 150 ? 97.950  139.436 95.128  1.00 22.99  ? 224 VAL C CB  1 
ATOM   5873 C CG1 . VAL C 1 150 ? 99.382  139.661 95.585  1.00 35.70  ? 224 VAL C CG1 1 
ATOM   5874 C CG2 . VAL C 1 150 ? 97.807  139.699 93.638  1.00 38.57  ? 224 VAL C CG2 1 
ATOM   5875 N N   . THR C 1 151 ? 95.766  137.295 93.906  1.00 32.15  ? 225 THR C N   1 
ATOM   5876 C CA  . THR C 1 151 ? 94.393  136.984 93.522  1.00 35.27  ? 225 THR C CA  1 
ATOM   5877 C C   . THR C 1 151 ? 93.826  135.854 94.373  1.00 43.15  ? 225 THR C C   1 
ATOM   5878 O O   . THR C 1 151 ? 92.688  135.936 94.850  1.00 46.01  ? 225 THR C O   1 
ATOM   5879 C CB  . THR C 1 151 ? 94.333  136.622 92.039  1.00 38.20  ? 225 THR C CB  1 
ATOM   5880 O OG1 . THR C 1 151 ? 94.801  137.728 91.257  1.00 45.81  ? 225 THR C OG1 1 
ATOM   5881 C CG2 . THR C 1 151 ? 92.908  136.286 91.628  1.00 40.84  ? 225 THR C CG2 1 
ATOM   5882 N N   . GLN C 1 152 ? 94.614  134.797 94.587  1.00 41.53  ? 226 GLN C N   1 
ATOM   5883 C CA  . GLN C 1 152 ? 94.150  133.676 95.396  1.00 37.49  ? 226 GLN C CA  1 
ATOM   5884 C C   . GLN C 1 152 ? 93.881  134.107 96.830  1.00 40.27  ? 226 GLN C C   1 
ATOM   5885 O O   . GLN C 1 152 ? 92.907  133.663 97.448  1.00 45.05  ? 226 GLN C O   1 
ATOM   5886 C CB  . GLN C 1 152 ? 95.176  132.544 95.361  1.00 33.89  ? 226 GLN C CB  1 
ATOM   5887 C CG  . GLN C 1 152 ? 95.097  131.670 94.121  1.00 45.14  ? 226 GLN C CG  1 
ATOM   5888 C CD  . GLN C 1 152 ? 93.682  131.223 93.812  1.00 50.22  ? 226 GLN C CD  1 
ATOM   5889 O OE1 . GLN C 1 152 ? 93.100  130.420 94.541  1.00 54.11  ? 226 GLN C OE1 1 
ATOM   5890 N NE2 . GLN C 1 152 ? 93.121  131.742 92.726  1.00 48.64  ? 226 GLN C NE2 1 
ATOM   5891 N N   . VAL C 1 153 ? 94.734  134.973 97.378  1.00 39.28  ? 227 VAL C N   1 
ATOM   5892 C CA  . VAL C 1 153 ? 94.519  135.445 98.743  1.00 35.42  ? 227 VAL C CA  1 
ATOM   5893 C C   . VAL C 1 153 ? 93.295  136.351 98.820  1.00 37.98  ? 227 VAL C C   1 
ATOM   5894 O O   . VAL C 1 153 ? 92.537  136.307 99.797  1.00 48.32  ? 227 VAL C O   1 
ATOM   5895 C CB  . VAL C 1 153 ? 95.787  136.133 99.273  1.00 38.05  ? 227 VAL C CB  1 
ATOM   5896 C CG1 . VAL C 1 153 ? 95.536  136.722 100.645 1.00 39.40  ? 227 VAL C CG1 1 
ATOM   5897 C CG2 . VAL C 1 153 ? 96.915  135.119 99.342  1.00 44.20  ? 227 VAL C CG2 1 
ATOM   5898 N N   . ILE C 1 154 ? 93.074  137.181 97.798  1.00 38.15  ? 228 ILE C N   1 
ATOM   5899 C CA  . ILE C 1 154 ? 91.885  138.030 97.774  1.00 33.24  ? 228 ILE C CA  1 
ATOM   5900 C C   . ILE C 1 154 ? 90.623  137.178 97.718  1.00 37.15  ? 228 ILE C C   1 
ATOM   5901 O O   . ILE C 1 154 ? 89.617  137.488 98.369  1.00 43.20  ? 228 ILE C O   1 
ATOM   5902 C CB  . ILE C 1 154 ? 91.957  139.023 96.599  1.00 35.86  ? 228 ILE C CB  1 
ATOM   5903 C CG1 . ILE C 1 154 ? 93.000  140.106 96.877  1.00 38.99  ? 228 ILE C CG1 1 
ATOM   5904 C CG2 . ILE C 1 154 ? 90.599  139.657 96.338  1.00 42.21  ? 228 ILE C CG2 1 
ATOM   5905 C CD1 . ILE C 1 154 ? 93.318  140.967 95.675  1.00 39.57  ? 228 ILE C CD1 1 
ATOM   5906 N N   . GLU C 1 155 ? 90.655  136.087 96.947  1.00 39.62  ? 229 GLU C N   1 
ATOM   5907 C CA  . GLU C 1 155 ? 89.490  135.209 96.866  1.00 40.10  ? 229 GLU C CA  1 
ATOM   5908 C C   . GLU C 1 155 ? 89.144  134.618 98.228  1.00 44.19  ? 229 GLU C C   1 
ATOM   5909 O O   . GLU C 1 155 ? 87.967  134.555 98.603  1.00 47.40  ? 229 GLU C O   1 
ATOM   5910 C CB  . GLU C 1 155 ? 89.732  134.097 95.847  1.00 41.64  ? 229 GLU C CB  1 
ATOM   5911 C CG  . GLU C 1 155 ? 89.902  134.585 94.420  1.00 48.65  ? 229 GLU C CG  1 
ATOM   5912 C CD  . GLU C 1 155 ? 88.860  135.614 94.029  1.00 52.56  ? 229 GLU C CD  1 
ATOM   5913 O OE1 . GLU C 1 155 ? 87.655  135.290 94.078  1.00 50.45  ? 229 GLU C OE1 1 
ATOM   5914 O OE2 . GLU C 1 155 ? 89.246  136.747 93.672  1.00 51.98  ? 229 GLU C OE2 1 
ATOM   5915 N N   . GLY C 1 156 ? 90.150  134.183 98.981  1.00 49.13  ? 230 GLY C N   1 
ATOM   5916 C CA  . GLY C 1 156 ? 89.913  133.657 100.311 1.00 46.87  ? 230 GLY C CA  1 
ATOM   5917 C C   . GLY C 1 156 ? 90.382  132.231 100.503 1.00 42.73  ? 230 GLY C C   1 
ATOM   5918 O O   . GLY C 1 156 ? 89.914  131.535 101.409 1.00 45.03  ? 230 GLY C O   1 
ATOM   5919 N N   . ASN C 1 157 ? 91.306  131.783 99.661  1.00 45.46  ? 231 ASN C N   1 
ATOM   5920 C CA  . ASN C 1 157 ? 91.867  130.436 99.739  1.00 51.60  ? 231 ASN C CA  1 
ATOM   5921 C C   . ASN C 1 157 ? 93.326  130.563 100.172 1.00 56.38  ? 231 ASN C C   1 
ATOM   5922 O O   . ASN C 1 157 ? 94.235  130.595 99.342  1.00 60.80  ? 231 ASN C O   1 
ATOM   5923 C CB  . ASN C 1 157 ? 91.738  129.712 98.402  1.00 53.75  ? 231 ASN C CB  1 
ATOM   5924 C CG  . ASN C 1 157 ? 90.302  129.366 98.062  1.00 59.84  ? 231 ASN C CG  1 
ATOM   5925 O OD1 . ASN C 1 157 ? 89.536  128.931 98.922  1.00 60.52  ? 231 ASN C OD1 1 
ATOM   5926 N ND2 . ASN C 1 157 ? 89.929  129.560 96.803  1.00 56.53  ? 231 ASN C ND2 1 
ATOM   5927 N N   . ALA C 1 158 ? 93.542  130.625 101.485 1.00 49.78  ? 232 ALA C N   1 
ATOM   5928 C CA  . ALA C 1 158 ? 94.879  130.766 102.043 1.00 46.69  ? 232 ALA C CA  1 
ATOM   5929 C C   . ALA C 1 158 ? 94.825  130.482 103.535 1.00 46.92  ? 232 ALA C C   1 
ATOM   5930 O O   . ALA C 1 158 ? 93.884  130.897 104.214 1.00 52.18  ? 232 ALA C O   1 
ATOM   5931 C CB  . ALA C 1 158 ? 95.443  132.171 101.793 1.00 46.50  ? 232 ALA C CB  1 
ATOM   5932 N N   . ALA C 1 159 ? 95.834  129.775 104.033 1.00 39.57  ? 233 ALA C N   1 
ATOM   5933 C CA  . ALA C 1 159 ? 95.958  129.500 105.456 1.00 43.01  ? 233 ALA C CA  1 
ATOM   5934 C C   . ALA C 1 159 ? 96.822  130.562 106.124 1.00 39.56  ? 233 ALA C C   1 
ATOM   5935 O O   . ALA C 1 159 ? 97.665  131.197 105.485 1.00 44.63  ? 233 ALA C O   1 
ATOM   5936 C CB  . ALA C 1 159 ? 96.553  128.112 105.692 1.00 43.39  ? 233 ALA C CB  1 
ATOM   5937 N N   . VAL C 1 160 ? 96.602  130.751 107.425 1.00 31.93  ? 234 VAL C N   1 
ATOM   5938 C CA  . VAL C 1 160 ? 97.287  131.784 108.189 1.00 32.33  ? 234 VAL C CA  1 
ATOM   5939 C C   . VAL C 1 160 ? 97.896  131.169 109.441 1.00 33.09  ? 234 VAL C C   1 
ATOM   5940 O O   . VAL C 1 160 ? 97.489  130.101 109.902 1.00 40.08  ? 234 VAL C O   1 
ATOM   5941 C CB  . VAL C 1 160 ? 96.348  132.950 108.571 1.00 30.82  ? 234 VAL C CB  1 
ATOM   5942 C CG1 . VAL C 1 160 ? 95.815  133.639 107.325 1.00 37.25  ? 234 VAL C CG1 1 
ATOM   5943 C CG2 . VAL C 1 160 ? 95.208  132.450 109.442 1.00 36.10  ? 234 VAL C CG2 1 
ATOM   5944 N N   . VAL C 1 161 ? 98.889  131.866 109.987 1.00 31.30  ? 235 VAL C N   1 
ATOM   5945 C CA  . VAL C 1 161 ? 99.532  131.494 111.242 1.00 22.27  ? 235 VAL C CA  1 
ATOM   5946 C C   . VAL C 1 161 ? 99.319  132.638 112.221 1.00 27.80  ? 235 VAL C C   1 
ATOM   5947 O O   . VAL C 1 161 ? 99.771  133.763 111.976 1.00 36.36  ? 235 VAL C O   1 
ATOM   5948 C CB  . VAL C 1 161 ? 101.030 131.206 111.057 1.00 22.93  ? 235 VAL C CB  1 
ATOM   5949 C CG1 . VAL C 1 161 ? 101.644 130.729 112.362 1.00 31.00  ? 235 VAL C CG1 1 
ATOM   5950 C CG2 . VAL C 1 161 ? 101.244 130.186 109.953 1.00 32.49  ? 235 VAL C CG2 1 
ATOM   5951 N N   . LEU C 1 162 ? 98.634  132.354 113.327 1.00 23.44  ? 236 LEU C N   1 
ATOM   5952 C CA  . LEU C 1 162 ? 98.323  133.371 114.331 1.00 20.67  ? 236 LEU C CA  1 
ATOM   5953 C C   . LEU C 1 162 ? 99.524  133.519 115.255 1.00 27.70  ? 236 LEU C C   1 
ATOM   5954 O O   . LEU C 1 162 ? 99.626  132.862 116.291 1.00 36.95  ? 236 LEU C O   1 
ATOM   5955 C CB  . LEU C 1 162 ? 97.063  133.002 115.101 1.00 28.30  ? 236 LEU C CB  1 
ATOM   5956 C CG  . LEU C 1 162 ? 95.796  132.828 114.264 1.00 30.44  ? 236 LEU C CG  1 
ATOM   5957 C CD1 . LEU C 1 162 ? 94.808  131.910 114.966 1.00 33.20  ? 236 LEU C CD1 1 
ATOM   5958 C CD2 . LEU C 1 162 ? 95.169  134.178 113.974 1.00 31.89  ? 236 LEU C CD2 1 
ATOM   5959 N N   . ARG C 1 163 ? 100.447 134.398 114.874 1.00 25.66  ? 237 ARG C N   1 
ATOM   5960 C CA  . ARG C 1 163 ? 101.623 134.648 115.694 1.00 22.36  ? 237 ARG C CA  1 
ATOM   5961 C C   . ARG C 1 163 ? 101.246 135.471 116.918 1.00 29.25  ? 237 ARG C C   1 
ATOM   5962 O O   . ARG C 1 163 ? 100.631 136.534 116.799 1.00 36.94  ? 237 ARG C O   1 
ATOM   5963 C CB  . ARG C 1 163 ? 102.693 135.373 114.882 1.00 21.84  ? 237 ARG C CB  1 
ATOM   5964 C CG  . ARG C 1 163 ? 102.851 134.863 113.465 1.00 20.89  ? 237 ARG C CG  1 
ATOM   5965 C CD  . ARG C 1 163 ? 104.074 135.467 112.805 1.00 20.63  ? 237 ARG C CD  1 
ATOM   5966 N NE  . ARG C 1 163 ? 104.564 134.643 111.709 1.00 20.05  ? 237 ARG C NE  1 
ATOM   5967 C CZ  . ARG C 1 163 ? 105.545 133.759 111.818 1.00 22.54  ? 237 ARG C CZ  1 
ATOM   5968 N NH1 . ARG C 1 163 ? 106.166 133.554 112.968 1.00 25.91  ? 237 ARG C NH1 1 
ATOM   5969 N NH2 . ARG C 1 163 ? 105.912 133.061 110.748 1.00 25.06  ? 237 ARG C NH2 1 
ATOM   5970 N N   . SER C 1 164 ? 101.618 134.979 118.095 1.00 21.69  ? 238 SER C N   1 
ATOM   5971 C CA  . SER C 1 164 ? 101.308 135.679 119.328 1.00 19.80  ? 238 SER C CA  1 
ATOM   5972 C C   . SER C 1 164 ? 102.214 136.895 119.502 1.00 26.56  ? 238 SER C C   1 
ATOM   5973 O O   . SER C 1 164 ? 103.317 136.969 118.954 1.00 30.47  ? 238 SER C O   1 
ATOM   5974 C CB  . SER C 1 164 ? 101.447 134.744 120.529 1.00 30.25  ? 238 SER C CB  1 
ATOM   5975 O OG  . SER C 1 164 ? 102.794 134.349 120.716 1.00 34.17  ? 238 SER C OG  1 
ATOM   5976 N N   . ARG C 1 165 ? 101.727 137.856 120.280 1.00 27.49  ? 239 ARG C N   1 
ATOM   5977 C CA  . ARG C 1 165 ? 102.459 139.074 120.586 1.00 22.28  ? 239 ARG C CA  1 
ATOM   5978 C C   . ARG C 1 165 ? 102.455 139.290 122.092 1.00 28.35  ? 239 ARG C C   1 
ATOM   5979 O O   . ARG C 1 165 ? 101.638 138.717 122.817 1.00 41.08  ? 239 ARG C O   1 
ATOM   5980 C CB  . ARG C 1 165 ? 101.852 140.291 119.876 1.00 27.88  ? 239 ARG C CB  1 
ATOM   5981 C CG  . ARG C 1 165 ? 101.931 140.234 118.361 1.00 24.39  ? 239 ARG C CG  1 
ATOM   5982 C CD  . ARG C 1 165 ? 101.639 141.590 117.748 1.00 24.11  ? 239 ARG C CD  1 
ATOM   5983 N NE  . ARG C 1 165 ? 100.316 142.079 118.115 1.00 28.53  ? 239 ARG C NE  1 
ATOM   5984 C CZ  . ARG C 1 165 ? 99.816  143.246 117.734 1.00 26.50  ? 239 ARG C CZ  1 
ATOM   5985 N NH1 . ARG C 1 165 ? 100.505 144.076 116.969 1.00 26.72  ? 239 ARG C NH1 1 
ATOM   5986 N NH2 . ARG C 1 165 ? 98.595  143.589 118.132 1.00 33.53  ? 239 ARG C NH2 1 
ATOM   5987 N N   . LEU C 1 166 ? 103.379 140.122 122.563 1.00 33.54  ? 240 LEU C N   1 
ATOM   5988 C CA  . LEU C 1 166 ? 103.496 140.418 123.985 1.00 21.54  ? 240 LEU C CA  1 
ATOM   5989 C C   . LEU C 1 166 ? 102.998 141.828 124.271 1.00 28.55  ? 240 LEU C C   1 
ATOM   5990 O O   . LEU C 1 166 ? 103.399 142.785 123.599 1.00 38.08  ? 240 LEU C O   1 
ATOM   5991 C CB  . LEU C 1 166 ? 104.936 140.263 124.475 1.00 23.29  ? 240 LEU C CB  1 
ATOM   5992 C CG  . LEU C 1 166 ? 105.560 138.870 124.441 1.00 32.05  ? 240 LEU C CG  1 
ATOM   5993 C CD1 . LEU C 1 166 ? 107.071 138.963 124.553 1.00 31.68  ? 240 LEU C CD1 1 
ATOM   5994 C CD2 . LEU C 1 166 ? 104.990 137.999 125.549 1.00 29.39  ? 240 LEU C CD2 1 
ATOM   5995 N N   . LYS C 1 167 ? 102.123 141.936 125.266 1.00 29.20  ? 241 LYS C N   1 
ATOM   5996 C CA  . LYS C 1 167 ? 101.646 143.209 125.789 1.00 22.10  ? 241 LYS C CA  1 
ATOM   5997 C C   . LYS C 1 167 ? 102.586 143.661 126.900 1.00 32.10  ? 241 LYS C C   1 
ATOM   5998 O O   . LYS C 1 167 ? 102.773 142.942 127.888 1.00 38.92  ? 241 LYS C O   1 
ATOM   5999 C CB  . LYS C 1 167 ? 100.221 143.055 126.318 1.00 30.29  ? 241 LYS C CB  1 
ATOM   6000 C CG  . LYS C 1 167 ? 99.567  144.326 126.821 1.00 29.28  ? 241 LYS C CG  1 
ATOM   6001 C CD  . LYS C 1 167 ? 98.141  144.035 127.267 1.00 33.11  ? 241 LYS C CD  1 
ATOM   6002 C CE  . LYS C 1 167 ? 97.413  145.294 127.696 1.00 37.84  ? 241 LYS C CE  1 
ATOM   6003 N NZ  . LYS C 1 167 ? 97.993  145.865 128.942 1.00 37.83  ? 241 LYS C NZ  1 
ATOM   6004 N N   . VAL C 1 168 ? 103.174 144.844 126.740 1.00 33.69  ? 242 VAL C N   1 
ATOM   6005 C CA  . VAL C 1 168 ? 104.182 145.360 127.657 1.00 25.52  ? 242 VAL C CA  1 
ATOM   6006 C C   . VAL C 1 168 ? 103.724 146.716 128.174 1.00 32.73  ? 242 VAL C C   1 
ATOM   6007 O O   . VAL C 1 168 ? 103.343 147.590 127.388 1.00 43.68  ? 242 VAL C O   1 
ATOM   6008 C CB  . VAL C 1 168 ? 105.557 145.474 126.977 1.00 29.53  ? 242 VAL C CB  1 
ATOM   6009 C CG1 . VAL C 1 168 ? 106.640 145.712 128.011 1.00 30.83  ? 242 VAL C CG1 1 
ATOM   6010 C CG2 . VAL C 1 168 ? 105.849 144.225 126.171 1.00 34.50  ? 242 VAL C CG2 1 
ATOM   6011 N N   . ARG C 1 169 ? 103.760 146.884 129.491 1.00 36.86  ? 243 ARG C N   1 
ATOM   6012 C CA  . ARG C 1 169 ? 103.456 148.150 130.143 1.00 34.51  ? 243 ARG C CA  1 
ATOM   6013 C C   . ARG C 1 169 ? 104.664 148.597 130.951 1.00 38.99  ? 243 ARG C C   1 
ATOM   6014 O O   . ARG C 1 169 ? 105.182 147.833 131.771 1.00 41.19  ? 243 ARG C O   1 
ATOM   6015 C CB  . ARG C 1 169 ? 102.232 148.029 131.053 1.00 40.80  ? 243 ARG C CB  1 
ATOM   6016 C CG  . ARG C 1 169 ? 101.025 147.380 130.405 1.00 44.08  ? 243 ARG C CG  1 
ATOM   6017 C CD  . ARG C 1 169 ? 99.837  147.389 131.350 1.00 43.13  ? 243 ARG C CD  1 
ATOM   6018 N NE  . ARG C 1 169 ? 99.791  148.608 132.148 1.00 46.09  ? 243 ARG C NE  1 
ATOM   6019 C CZ  . ARG C 1 169 ? 99.241  148.695 133.352 1.00 48.86  ? 243 ARG C CZ  1 
ATOM   6020 N NH1 . ARG C 1 169 ? 98.678  147.648 133.932 1.00 46.51  ? 243 ARG C NH1 1 
ATOM   6021 N NH2 . ARG C 1 169 ? 99.258  149.862 133.990 1.00 46.94  ? 243 ARG C NH2 1 
ATOM   6022 N N   . VAL C 1 170 ? 105.106 149.828 130.726 1.00 41.92  ? 244 VAL C N   1 
ATOM   6023 C CA  . VAL C 1 170 ? 106.223 150.407 131.461 1.00 37.49  ? 244 VAL C CA  1 
ATOM   6024 C C   . VAL C 1 170 ? 105.661 151.411 132.456 1.00 43.07  ? 244 VAL C C   1 
ATOM   6025 O O   . VAL C 1 170 ? 105.023 152.395 132.064 1.00 47.51  ? 244 VAL C O   1 
ATOM   6026 C CB  . VAL C 1 170 ? 107.238 151.070 130.517 1.00 33.83  ? 244 VAL C CB  1 
ATOM   6027 C CG1 . VAL C 1 170 ? 108.451 151.550 131.296 1.00 41.95  ? 244 VAL C CG1 1 
ATOM   6028 C CG2 . VAL C 1 170 ? 107.651 150.103 129.422 1.00 38.58  ? 244 VAL C CG2 1 
ATOM   6029 N N   . VAL C 1 171 ? 105.893 151.166 133.743 1.00 48.49  ? 245 VAL C N   1 
ATOM   6030 C CA  . VAL C 1 171 ? 105.408 152.029 134.812 1.00 45.30  ? 245 VAL C CA  1 
ATOM   6031 C C   . VAL C 1 171 ? 106.604 152.762 135.400 1.00 48.34  ? 245 VAL C C   1 
ATOM   6032 O O   . VAL C 1 171 ? 107.566 152.131 135.856 1.00 54.34  ? 245 VAL C O   1 
ATOM   6033 C CB  . VAL C 1 171 ? 104.660 151.233 135.892 1.00 48.63  ? 245 VAL C CB  1 
ATOM   6034 C CG1 . VAL C 1 171 ? 104.004 152.177 136.886 1.00 50.52  ? 245 VAL C CG1 1 
ATOM   6035 C CG2 . VAL C 1 171 ? 103.627 150.318 135.255 1.00 48.18  ? 245 VAL C CG2 1 
ATOM   6036 N N   . LYS C 1 172 ? 106.543 154.091 135.389 1.00 53.61  ? 246 LYS C N   1 
ATOM   6037 C CA  . LYS C 1 172 ? 107.619 154.939 135.881 1.00 56.82  ? 246 LYS C CA  1 
ATOM   6038 C C   . LYS C 1 172 ? 107.138 155.714 137.098 1.00 63.04  ? 246 LYS C C   1 
ATOM   6039 O O   . LYS C 1 172 ? 106.036 156.274 137.087 1.00 61.39  ? 246 LYS C O   1 
ATOM   6040 C CB  . LYS C 1 172 ? 108.104 155.902 134.795 1.00 52.62  ? 246 LYS C CB  1 
ATOM   6041 C CG  . LYS C 1 172 ? 108.792 155.221 133.625 1.00 52.75  ? 246 LYS C CG  1 
ATOM   6042 C CD  . LYS C 1 172 ? 109.306 156.238 132.620 1.00 56.09  ? 246 LYS C CD  1 
ATOM   6043 C CE  . LYS C 1 172 ? 109.921 155.555 131.409 1.00 58.30  ? 246 LYS C CE  1 
ATOM   6044 N NZ  . LYS C 1 172 ? 111.176 154.834 131.754 1.00 58.17  ? 246 LYS C NZ  1 
ATOM   6045 N N   . GLU C 1 173 ? 107.962 155.744 138.139 1.00 72.59  ? 247 GLU C N   1 
ATOM   6046 C CA  . GLU C 1 173 ? 107.627 156.459 139.365 1.00 70.30  ? 247 GLU C CA  1 
ATOM   6047 C C   . GLU C 1 173 ? 108.178 157.880 139.336 1.00 70.28  ? 247 GLU C C   1 
ATOM   6048 O O   . GLU C 1 173 ? 109.263 158.124 138.810 1.00 72.14  ? 247 GLU C O   1 
ATOM   6049 C CB  . GLU C 1 173 ? 108.164 155.710 140.586 1.00 68.72  ? 247 GLU C CB  1 
ATOM   6050 C CG  . GLU C 1 173 ? 107.797 156.348 141.917 1.00 71.58  ? 247 GLU C CG  1 
ATOM   6051 C CD  . GLU C 1 173 ? 108.306 155.550 143.103 1.00 74.01  ? 247 GLU C CD  1 
ATOM   6052 O OE1 . GLU C 1 173 ? 108.976 154.520 142.885 1.00 72.43  ? 247 GLU C OE1 1 
ATOM   6053 O OE2 . GLU C 1 173 ? 108.032 155.953 144.254 1.00 73.13  ? 247 GLU C OE2 1 
ATOM   6054 N N   . ALA C 1 203 ? 102.131 154.772 132.074 1.00 51.44  ? 277 ALA C N   1 
ATOM   6055 C CA  . ALA C 1 203 ? 101.989 153.591 131.231 1.00 56.65  ? 277 ALA C CA  1 
ATOM   6056 C C   . ALA C 1 203 ? 102.442 153.882 129.805 1.00 53.28  ? 277 ALA C C   1 
ATOM   6057 O O   . ALA C 1 203 ? 102.393 155.023 129.349 1.00 53.98  ? 277 ALA C O   1 
ATOM   6058 C CB  . ALA C 1 203 ? 100.549 153.103 131.241 1.00 55.67  ? 277 ALA C CB  1 
ATOM   6059 N N   . MET C 1 204 ? 102.883 152.842 129.105 1.00 50.99  ? 278 MET C N   1 
ATOM   6060 C CA  . MET C 1 204 ? 103.348 152.967 127.729 1.00 51.45  ? 278 MET C CA  1 
ATOM   6061 C C   . MET C 1 204 ? 102.556 152.115 126.751 1.00 55.93  ? 278 MET C C   1 
ATOM   6062 O O   . MET C 1 204 ? 102.280 152.568 125.636 1.00 59.76  ? 278 MET C O   1 
ATOM   6063 C CB  . MET C 1 204 ? 104.838 152.603 127.643 1.00 51.80  ? 278 MET C CB  1 
ATOM   6064 C CG  . MET C 1 204 ? 105.790 153.613 128.291 1.00 55.71  ? 278 MET C CG  1 
ATOM   6065 S SD  . MET C 1 204 ? 105.408 155.374 128.102 1.00 66.88  ? 278 MET C SD  1 
ATOM   6066 C CE  . MET C 1 204 ? 105.142 155.535 126.333 1.00 55.25  ? 278 MET C CE  1 
ATOM   6067 N N   . GLN C 1 205 ? 102.183 150.894 127.140 1.00 46.67  ? 279 GLN C N   1 
ATOM   6068 C CA  . GLN C 1 205 ? 101.249 150.051 126.390 1.00 40.31  ? 279 GLN C CA  1 
ATOM   6069 C C   . GLN C 1 205 ? 101.767 149.766 124.974 1.00 41.75  ? 279 GLN C C   1 
ATOM   6070 O O   . GLN C 1 205 ? 101.214 150.208 123.965 1.00 49.51  ? 279 GLN C O   1 
ATOM   6071 C CB  . GLN C 1 205 ? 99.854  150.690 126.368 1.00 46.03  ? 279 GLN C CB  1 
ATOM   6072 C CG  . GLN C 1 205 ? 98.774  149.823 125.747 1.00 48.95  ? 279 GLN C CG  1 
ATOM   6073 C CD  . GLN C 1 205 ? 98.581  148.523 126.496 1.00 45.73  ? 279 GLN C CD  1 
ATOM   6074 O OE1 . GLN C 1 205 ? 99.004  147.464 126.037 1.00 49.78  ? 279 GLN C OE1 1 
ATOM   6075 N NE2 . GLN C 1 205 ? 97.944  148.597 127.658 1.00 45.78  ? 279 GLN C NE2 1 
ATOM   6076 N N   . TYR C 1 206 ? 102.871 149.027 124.933 1.00 38.85  ? 280 TYR C N   1 
ATOM   6077 C CA  . TYR C 1 206 ? 103.422 148.535 123.679 1.00 34.08  ? 280 TYR C CA  1 
ATOM   6078 C C   . TYR C 1 206 ? 102.958 147.109 123.402 1.00 40.14  ? 280 TYR C C   1 
ATOM   6079 O O   . TYR C 1 206 ? 102.664 146.338 124.319 1.00 44.20  ? 280 TYR C O   1 
ATOM   6080 C CB  . TYR C 1 206 ? 104.952 148.569 123.697 1.00 35.63  ? 280 TYR C CB  1 
ATOM   6081 C CG  . TYR C 1 206 ? 105.558 149.950 123.784 1.00 39.16  ? 280 TYR C CG  1 
ATOM   6082 C CD1 . TYR C 1 206 ? 105.517 150.816 122.701 1.00 43.56  ? 280 TYR C CD1 1 
ATOM   6083 C CD2 . TYR C 1 206 ? 106.196 150.376 124.940 1.00 40.37  ? 280 TYR C CD2 1 
ATOM   6084 C CE1 . TYR C 1 206 ? 106.077 152.077 122.773 1.00 44.02  ? 280 TYR C CE1 1 
ATOM   6085 C CE2 . TYR C 1 206 ? 106.762 151.632 125.020 1.00 36.42  ? 280 TYR C CE2 1 
ATOM   6086 C CZ  . TYR C 1 206 ? 106.698 152.479 123.936 1.00 43.02  ? 280 TYR C CZ  1 
ATOM   6087 O OH  . TYR C 1 206 ? 107.260 153.732 124.015 1.00 45.45  ? 280 TYR C OH  1 
ATOM   6088 N N   . GLN C 1 207 ? 102.883 146.770 122.118 1.00 37.72  ? 281 GLN C N   1 
ATOM   6089 C CA  . GLN C 1 207 ? 102.727 145.395 121.663 1.00 26.87  ? 281 GLN C CA  1 
ATOM   6090 C C   . GLN C 1 207 ? 103.944 145.027 120.831 1.00 30.05  ? 281 GLN C C   1 
ATOM   6091 O O   . GLN C 1 207 ? 104.295 145.746 119.889 1.00 43.05  ? 281 GLN C O   1 
ATOM   6092 C CB  . GLN C 1 207 ? 101.447 145.205 120.844 1.00 29.16  ? 281 GLN C CB  1 
ATOM   6093 C CG  . GLN C 1 207 ? 100.263 146.021 121.318 1.00 35.52  ? 281 GLN C CG  1 
ATOM   6094 C CD  . GLN C 1 207 ? 99.504  145.342 122.439 1.00 38.42  ? 281 GLN C CD  1 
ATOM   6095 O OE1 . GLN C 1 207 ? 99.323  144.125 122.430 1.00 38.07  ? 281 GLN C OE1 1 
ATOM   6096 N NE2 . GLN C 1 207 ? 99.058  146.125 123.413 1.00 41.40  ? 281 GLN C NE2 1 
ATOM   6097 N N   . VAL C 1 208 ? 104.587 143.916 121.175 1.00 25.85  ? 282 VAL C N   1 
ATOM   6098 C CA  . VAL C 1 208 ? 105.812 143.508 120.501 1.00 20.65  ? 282 VAL C CA  1 
ATOM   6099 C C   . VAL C 1 208 ? 105.604 142.153 119.845 1.00 21.86  ? 282 VAL C C   1 
ATOM   6100 O O   . VAL C 1 208 ? 104.804 141.329 120.302 1.00 30.17  ? 282 VAL C O   1 
ATOM   6101 C CB  . VAL C 1 208 ? 107.018 143.462 121.461 1.00 26.58  ? 282 VAL C CB  1 
ATOM   6102 C CG1 . VAL C 1 208 ? 107.330 144.850 121.981 1.00 33.26  ? 282 VAL C CG1 1 
ATOM   6103 C CG2 . VAL C 1 208 ? 106.749 142.509 122.593 1.00 32.81  ? 282 VAL C CG2 1 
ATOM   6104 N N   . LEU C 1 209 ? 106.352 141.924 118.766 1.00 30.43  ? 283 LEU C N   1 
ATOM   6105 C CA  . LEU C 1 209 ? 106.250 140.720 117.951 1.00 29.90  ? 283 LEU C CA  1 
ATOM   6106 C C   . LEU C 1 209 ? 107.342 139.701 118.255 1.00 33.97  ? 283 LEU C C   1 
ATOM   6107 O O   . LEU C 1 209 ? 107.043 138.523 118.467 1.00 40.30  ? 283 LEU C O   1 
ATOM   6108 C CB  . LEU C 1 209 ? 106.293 141.094 116.465 1.00 35.91  ? 283 LEU C CB  1 
ATOM   6109 C CG  . LEU C 1 209 ? 106.122 139.956 115.457 1.00 33.20  ? 283 LEU C CG  1 
ATOM   6110 C CD1 . LEU C 1 209 ? 104.843 139.178 115.723 1.00 34.58  ? 283 LEU C CD1 1 
ATOM   6111 C CD2 . LEU C 1 209 ? 106.149 140.495 114.038 1.00 34.18  ? 283 LEU C CD2 1 
ATOM   6112 N N   . ASN C 1 210 ? 108.606 140.125 118.282 1.00 33.99  ? 284 ASN C N   1 
ATOM   6113 C CA  . ASN C 1 210 ? 109.699 139.181 118.493 1.00 33.52  ? 284 ASN C CA  1 
ATOM   6114 C C   . ASN C 1 210 ? 110.088 139.062 119.967 1.00 40.28  ? 284 ASN C C   1 
ATOM   6115 O O   . ASN C 1 210 ? 109.979 137.979 120.551 1.00 44.12  ? 284 ASN C O   1 
ATOM   6116 C CB  . ASN C 1 210 ? 110.911 139.574 117.641 1.00 32.83  ? 284 ASN C CB  1 
ATOM   6117 C CG  . ASN C 1 210 ? 110.738 139.233 116.181 1.00 38.74  ? 284 ASN C CG  1 
ATOM   6118 O OD1 . ASN C 1 210 ? 110.180 138.193 115.834 1.00 43.01  ? 284 ASN C OD1 1 
ATOM   6119 N ND2 . ASN C 1 210 ? 111.256 140.090 115.313 1.00 42.48  ? 284 ASN C ND2 1 
ATOM   6120 N N   . GLU C 1 211 ? 110.533 140.156 120.587 1.00 39.73  ? 285 GLU C N   1 
ATOM   6121 C CA  . GLU C 1 211 ? 110.852 140.118 122.010 1.00 32.02  ? 285 GLU C CA  1 
ATOM   6122 C C   . GLU C 1 211 ? 110.841 141.531 122.579 1.00 29.93  ? 285 GLU C C   1 
ATOM   6123 O O   . GLU C 1 211 ? 110.636 142.517 121.867 1.00 40.58  ? 285 GLU C O   1 
ATOM   6124 C CB  . GLU C 1 211 ? 112.220 139.489 122.300 1.00 39.96  ? 285 GLU C CB  1 
ATOM   6125 C CG  . GLU C 1 211 ? 113.425 140.313 121.859 1.00 39.74  ? 285 GLU C CG  1 
ATOM   6126 C CD  . GLU C 1 211 ? 113.822 140.110 120.420 1.00 39.94  ? 285 GLU C CD  1 
ATOM   6127 O OE1 . GLU C 1 211 ? 113.021 139.562 119.652 1.00 45.54  ? 285 GLU C OE1 1 
ATOM   6128 O OE2 . GLU C 1 211 ? 114.948 140.506 120.056 1.00 45.49  ? 285 GLU C OE2 1 
ATOM   6129 N N   . VAL C 1 212 ? 111.069 141.606 123.889 1.00 32.99  ? 286 VAL C N   1 
ATOM   6130 C CA  . VAL C 1 212 ? 111.461 142.824 124.587 1.00 33.67  ? 286 VAL C CA  1 
ATOM   6131 C C   . VAL C 1 212 ? 112.806 142.559 125.244 1.00 32.75  ? 286 VAL C C   1 
ATOM   6132 O O   . VAL C 1 212 ? 112.947 141.596 126.006 1.00 34.35  ? 286 VAL C O   1 
ATOM   6133 C CB  . VAL C 1 212 ? 110.420 143.246 125.638 1.00 27.02  ? 286 VAL C CB  1 
ATOM   6134 C CG1 . VAL C 1 212 ? 110.916 144.446 126.418 1.00 38.06  ? 286 VAL C CG1 1 
ATOM   6135 C CG2 . VAL C 1 212 ? 109.113 143.569 124.968 1.00 34.27  ? 286 VAL C CG2 1 
ATOM   6136 N N   . VAL C 1 213 ? 113.790 143.406 124.955 1.00 32.77  ? 287 VAL C N   1 
ATOM   6137 C CA  . VAL C 1 213 ? 115.157 143.200 125.421 1.00 29.62  ? 287 VAL C CA  1 
ATOM   6138 C C   . VAL C 1 213 ? 115.467 144.232 126.495 1.00 35.63  ? 287 VAL C C   1 
ATOM   6139 O O   . VAL C 1 213 ? 115.391 145.441 126.247 1.00 44.29  ? 287 VAL C O   1 
ATOM   6140 C CB  . VAL C 1 213 ? 116.171 143.290 124.271 1.00 34.01  ? 287 VAL C CB  1 
ATOM   6141 C CG1 . VAL C 1 213 ? 117.582 143.420 124.821 1.00 35.51  ? 287 VAL C CG1 1 
ATOM   6142 C CG2 . VAL C 1 213 ? 116.068 142.074 123.378 1.00 36.46  ? 287 VAL C CG2 1 
ATOM   6143 N N   . ILE C 1 214 ? 115.827 143.756 127.681 1.00 37.94  ? 288 ILE C N   1 
ATOM   6144 C CA  . ILE C 1 214 ? 116.413 144.593 128.719 1.00 35.86  ? 288 ILE C CA  1 
ATOM   6145 C C   . ILE C 1 214 ? 117.911 144.328 128.732 1.00 35.09  ? 288 ILE C C   1 
ATOM   6146 O O   . ILE C 1 214 ? 118.348 143.173 128.656 1.00 40.82  ? 288 ILE C O   1 
ATOM   6147 C CB  . ILE C 1 214 ? 115.774 144.329 130.094 1.00 25.95  ? 288 ILE C CB  1 
ATOM   6148 C CG1 . ILE C 1 214 ? 116.289 145.338 131.120 1.00 38.86  ? 288 ILE C CG1 1 
ATOM   6149 C CG2 . ILE C 1 214 ? 116.020 142.909 130.562 1.00 38.21  ? 288 ILE C CG2 1 
ATOM   6150 C CD1 . ILE C 1 214 ? 115.518 145.333 132.409 1.00 42.19  ? 288 ILE C CD1 1 
ATOM   6151 N N   . ASP C 1 215 ? 118.699 145.395 128.772 1.00 42.08  ? 289 ASP C N   1 
ATOM   6152 C CA  . ASP C 1 215 ? 120.144 145.269 128.645 1.00 40.36  ? 289 ASP C CA  1 
ATOM   6153 C C   . ASP C 1 215 ? 120.805 146.510 129.231 1.00 48.18  ? 289 ASP C C   1 
ATOM   6154 O O   . ASP C 1 215 ? 120.171 147.306 129.933 1.00 55.43  ? 289 ASP C O   1 
ATOM   6155 C CB  . ASP C 1 215 ? 120.542 145.038 127.182 1.00 45.81  ? 289 ASP C CB  1 
ATOM   6156 C CG  . ASP C 1 215 ? 120.245 146.234 126.294 1.00 53.40  ? 289 ASP C CG  1 
ATOM   6157 O OD1 . ASP C 1 215 ? 119.453 147.109 126.704 1.00 54.45  ? 289 ASP C OD1 1 
ATOM   6158 O OD2 . ASP C 1 215 ? 120.807 146.299 125.181 1.00 54.37  ? 289 ASP C OD2 1 
ATOM   6159 N N   . ARG C 1 216 ? 122.093 146.665 128.944 1.00 51.11  ? 290 ARG C N   1 
ATOM   6160 C CA  . ARG C 1 216 ? 122.875 147.819 129.355 1.00 48.66  ? 290 ARG C CA  1 
ATOM   6161 C C   . ARG C 1 216 ? 123.265 148.621 128.123 1.00 49.79  ? 290 ARG C C   1 
ATOM   6162 O O   . ARG C 1 216 ? 123.522 148.053 127.057 1.00 52.29  ? 290 ARG C O   1 
ATOM   6163 C CB  . ARG C 1 216 ? 124.134 147.392 130.113 1.00 51.34  ? 290 ARG C CB  1 
ATOM   6164 C CG  . ARG C 1 216 ? 124.723 146.073 129.643 1.00 52.22  ? 290 ARG C CG  1 
ATOM   6165 C CD  . ARG C 1 216 ? 126.157 145.920 130.120 1.00 55.37  ? 290 ARG C CD  1 
ATOM   6166 N NE  . ARG C 1 216 ? 126.760 144.667 129.685 1.00 54.84  ? 290 ARG C NE  1 
ATOM   6167 C CZ  . ARG C 1 216 ? 127.594 144.555 128.660 1.00 53.41  ? 290 ARG C CZ  1 
ATOM   6168 N NH1 . ARG C 1 216 ? 127.937 145.604 127.931 1.00 54.61  ? 290 ARG C NH1 1 
ATOM   6169 N NH2 . ARG C 1 216 ? 128.100 143.362 128.361 1.00 53.63  ? 290 ARG C NH2 1 
ATOM   6170 N N   . GLY C 1 217 ? 123.309 149.940 128.271 1.00 63.37  ? 291 GLY C N   1 
ATOM   6171 C CA  . GLY C 1 217 ? 123.664 150.809 127.177 1.00 63.42  ? 291 GLY C CA  1 
ATOM   6172 C C   . GLY C 1 217 ? 125.142 151.134 127.182 1.00 61.96  ? 291 GLY C C   1 
ATOM   6173 O O   . GLY C 1 217 ? 125.990 150.283 126.895 1.00 61.31  ? 291 GLY C O   1 
ATOM   6174 N N   . PRO C 1 218 ? 125.481 152.382 127.506 1.00 63.70  ? 292 PRO C N   1 
ATOM   6175 C CA  . PRO C 1 218 ? 126.901 152.754 127.599 1.00 66.04  ? 292 PRO C CA  1 
ATOM   6176 C C   . PRO C 1 218 ? 127.643 152.037 128.713 1.00 64.29  ? 292 PRO C C   1 
ATOM   6177 O O   . PRO C 1 218 ? 128.881 152.032 128.707 1.00 64.37  ? 292 PRO C O   1 
ATOM   6178 C CB  . PRO C 1 218 ? 126.852 154.269 127.842 1.00 66.16  ? 292 PRO C CB  1 
ATOM   6179 C CG  . PRO C 1 218 ? 125.504 154.507 128.447 1.00 66.06  ? 292 PRO C CG  1 
ATOM   6180 C CD  . PRO C 1 218 ? 124.589 153.520 127.783 1.00 63.11  ? 292 PRO C CD  1 
ATOM   6181 N N   . SER C 1 219 ? 126.932 151.439 129.667 1.00 60.48  ? 293 SER C N   1 
ATOM   6182 C CA  . SER C 1 219 ? 127.583 150.775 130.787 1.00 59.33  ? 293 SER C CA  1 
ATOM   6183 C C   . SER C 1 219 ? 128.391 149.573 130.314 1.00 59.04  ? 293 SER C C   1 
ATOM   6184 O O   . SER C 1 219 ? 127.940 148.787 129.477 1.00 60.34  ? 293 SER C O   1 
ATOM   6185 C CB  . SER C 1 219 ? 126.541 150.332 131.815 1.00 59.07  ? 293 SER C CB  1 
ATOM   6186 O OG  . SER C 1 219 ? 127.115 149.479 132.788 1.00 59.53  ? 293 SER C OG  1 
ATOM   6187 N N   . SER C 1 220 ? 129.598 149.438 130.859 1.00 71.22  ? 294 SER C N   1 
ATOM   6188 C CA  . SER C 1 220 ? 130.466 148.304 130.577 1.00 74.65  ? 294 SER C CA  1 
ATOM   6189 C C   . SER C 1 220 ? 130.514 147.301 131.721 1.00 71.87  ? 294 SER C C   1 
ATOM   6190 O O   . SER C 1 220 ? 131.198 146.280 131.604 1.00 72.36  ? 294 SER C O   1 
ATOM   6191 C CB  . SER C 1 220 ? 131.884 148.790 130.257 1.00 72.37  ? 294 SER C CB  1 
ATOM   6192 O OG  . SER C 1 220 ? 131.902 149.568 129.073 1.00 71.74  ? 294 SER C OG  1 
ATOM   6193 N N   . TYR C 1 221 ? 129.808 147.566 132.817 1.00 68.68  ? 295 TYR C N   1 
ATOM   6194 C CA  . TYR C 1 221 ? 129.768 146.658 133.949 1.00 69.72  ? 295 TYR C CA  1 
ATOM   6195 C C   . TYR C 1 221 ? 128.583 145.705 133.815 1.00 68.70  ? 295 TYR C C   1 
ATOM   6196 O O   . TYR C 1 221 ? 127.751 145.824 132.913 1.00 66.13  ? 295 TYR C O   1 
ATOM   6197 C CB  . TYR C 1 221 ? 129.698 147.440 135.260 1.00 70.22  ? 295 TYR C CB  1 
ATOM   6198 C CG  . TYR C 1 221 ? 130.729 148.538 135.376 1.00 75.12  ? 295 TYR C CG  1 
ATOM   6199 C CD1 . TYR C 1 221 ? 132.072 148.238 135.566 1.00 73.31  ? 295 TYR C CD1 1 
ATOM   6200 C CD2 . TYR C 1 221 ? 130.361 149.874 135.297 1.00 72.50  ? 295 TYR C CD2 1 
ATOM   6201 C CE1 . TYR C 1 221 ? 133.019 149.238 135.673 1.00 72.96  ? 295 TYR C CE1 1 
ATOM   6202 C CE2 . TYR C 1 221 ? 131.301 150.881 135.403 1.00 71.99  ? 295 TYR C CE2 1 
ATOM   6203 C CZ  . TYR C 1 221 ? 132.628 150.558 135.591 1.00 74.47  ? 295 TYR C CZ  1 
ATOM   6204 O OH  . TYR C 1 221 ? 133.567 151.557 135.698 1.00 71.30  ? 295 TYR C OH  1 
ATOM   6205 N N   . LEU C 1 222 ? 128.506 144.741 134.726 1.00 59.52  ? 296 LEU C N   1 
ATOM   6206 C CA  . LEU C 1 222 ? 127.431 143.765 134.689 1.00 55.40  ? 296 LEU C CA  1 
ATOM   6207 C C   . LEU C 1 222 ? 126.112 144.414 135.101 1.00 55.00  ? 296 LEU C C   1 
ATOM   6208 O O   . LEU C 1 222 ? 126.076 145.420 135.815 1.00 58.94  ? 296 LEU C O   1 
ATOM   6209 C CB  . LEU C 1 222 ? 127.749 142.579 135.600 1.00 54.15  ? 296 LEU C CB  1 
ATOM   6210 C CG  . LEU C 1 222 ? 128.625 141.472 135.003 1.00 51.37  ? 296 LEU C CG  1 
ATOM   6211 C CD1 . LEU C 1 222 ? 130.054 141.955 134.810 1.00 55.69  ? 296 LEU C CD1 1 
ATOM   6212 C CD2 . LEU C 1 222 ? 128.602 140.224 135.865 1.00 54.34  ? 296 LEU C CD2 1 
ATOM   6213 N N   . SER C 1 223 ? 125.016 143.822 134.637 1.00 51.31  ? 297 SER C N   1 
ATOM   6214 C CA  . SER C 1 223 ? 123.674 144.329 134.885 1.00 50.63  ? 297 SER C CA  1 
ATOM   6215 C C   . SER C 1 223 ? 122.906 143.332 135.738 1.00 52.38  ? 297 SER C C   1 
ATOM   6216 O O   . SER C 1 223 ? 122.874 142.138 135.424 1.00 52.33  ? 297 SER C O   1 
ATOM   6217 C CB  . SER C 1 223 ? 122.934 144.583 133.570 1.00 51.43  ? 297 SER C CB  1 
ATOM   6218 O OG  . SER C 1 223 ? 121.615 145.044 133.806 1.00 55.28  ? 297 SER C OG  1 
ATOM   6219 N N   . ASN C 1 224 ? 122.293 143.827 136.813 1.00 54.22  ? 298 ASN C N   1 
ATOM   6220 C CA  . ASN C 1 224 ? 121.499 143.025 137.739 1.00 48.99  ? 298 ASN C CA  1 
ATOM   6221 C C   . ASN C 1 224 ? 120.043 143.448 137.605 1.00 46.46  ? 298 ASN C C   1 
ATOM   6222 O O   . ASN C 1 224 ? 119.695 144.584 137.943 1.00 48.49  ? 298 ASN C O   1 
ATOM   6223 C CB  . ASN C 1 224 ? 121.972 143.222 139.178 1.00 45.09  ? 298 ASN C CB  1 
ATOM   6224 C CG  . ASN C 1 224 ? 123.315 142.591 139.445 1.00 51.05  ? 298 ASN C CG  1 
ATOM   6225 O OD1 . ASN C 1 224 ? 123.578 141.473 139.016 1.00 52.44  ? 298 ASN C OD1 1 
ATOM   6226 N ND2 . ASN C 1 224 ? 124.176 143.306 140.159 1.00 52.52  ? 298 ASN C ND2 1 
ATOM   6227 N N   . VAL C 1 225 ? 119.187 142.547 137.124 1.00 40.95  ? 299 VAL C N   1 
ATOM   6228 C CA  . VAL C 1 225 ? 117.754 142.835 137.091 1.00 38.36  ? 299 VAL C CA  1 
ATOM   6229 C C   . VAL C 1 225 ? 116.974 141.650 137.646 1.00 41.71  ? 299 VAL C C   1 
ATOM   6230 O O   . VAL C 1 225 ? 117.300 140.488 137.376 1.00 44.93  ? 299 VAL C O   1 
ATOM   6231 C CB  . VAL C 1 225 ? 117.248 143.223 135.679 1.00 38.33  ? 299 VAL C CB  1 
ATOM   6232 C CG1 . VAL C 1 225 ? 117.935 144.487 135.186 1.00 43.38  ? 299 VAL C CG1 1 
ATOM   6233 C CG2 . VAL C 1 225 ? 117.439 142.114 134.691 1.00 40.44  ? 299 VAL C CG2 1 
ATOM   6234 N N   . ASP C 1 226 ? 115.947 141.959 138.438 1.00 42.62  ? 300 ASP C N   1 
ATOM   6235 C CA  . ASP C 1 226 ? 115.088 140.965 139.066 1.00 36.34  ? 300 ASP C CA  1 
ATOM   6236 C C   . ASP C 1 226 ? 113.883 140.702 138.175 1.00 35.21  ? 300 ASP C C   1 
ATOM   6237 O O   . ASP C 1 226 ? 113.337 141.631 137.565 1.00 43.39  ? 300 ASP C O   1 
ATOM   6238 C CB  . ASP C 1 226 ? 114.601 141.461 140.430 1.00 42.80  ? 300 ASP C CB  1 
ATOM   6239 C CG  . ASP C 1 226 ? 115.564 141.142 141.551 1.00 51.45  ? 300 ASP C CG  1 
ATOM   6240 O OD1 . ASP C 1 226 ? 116.748 140.891 141.262 1.00 50.85  ? 300 ASP C OD1 1 
ATOM   6241 O OD2 . ASP C 1 226 ? 115.135 141.142 142.724 1.00 52.58  ? 300 ASP C OD2 1 
ATOM   6242 N N   . VAL C 1 227 ? 113.452 139.440 138.109 1.00 29.83  ? 301 VAL C N   1 
ATOM   6243 C CA  . VAL C 1 227 ? 112.253 139.084 137.358 1.00 29.01  ? 301 VAL C CA  1 
ATOM   6244 C C   . VAL C 1 227 ? 111.256 138.404 138.289 1.00 31.76  ? 301 VAL C C   1 
ATOM   6245 O O   . VAL C 1 227 ? 111.623 137.545 139.098 1.00 37.89  ? 301 VAL C O   1 
ATOM   6246 C CB  . VAL C 1 227 ? 112.576 138.199 136.133 1.00 29.47  ? 301 VAL C CB  1 
ATOM   6247 C CG1 . VAL C 1 227 ? 113.485 138.945 135.171 1.00 35.78  ? 301 VAL C CG1 1 
ATOM   6248 C CG2 . VAL C 1 227 ? 113.228 136.908 136.550 1.00 32.46  ? 301 VAL C CG2 1 
ATOM   6249 N N   . TYR C 1 228 ? 109.996 138.823 138.189 1.00 30.74  ? 302 TYR C N   1 
ATOM   6250 C CA  . TYR C 1 228 ? 108.883 138.265 138.939 1.00 24.04  ? 302 TYR C CA  1 
ATOM   6251 C C   . TYR C 1 228 ? 107.994 137.480 137.987 1.00 28.43  ? 302 TYR C C   1 
ATOM   6252 O O   . TYR C 1 228 ? 107.688 137.952 136.887 1.00 39.99  ? 302 TYR C O   1 
ATOM   6253 C CB  . TYR C 1 228 ? 108.029 139.360 139.589 1.00 28.67  ? 302 TYR C CB  1 
ATOM   6254 C CG  . TYR C 1 228 ? 108.692 140.197 140.657 1.00 23.14  ? 302 TYR C CG  1 
ATOM   6255 C CD1 . TYR C 1 228 ? 109.890 139.817 141.236 1.00 27.71  ? 302 TYR C CD1 1 
ATOM   6256 C CD2 . TYR C 1 228 ? 108.101 141.378 141.091 1.00 33.63  ? 302 TYR C CD2 1 
ATOM   6257 C CE1 . TYR C 1 228 ? 110.483 140.594 142.212 1.00 28.24  ? 302 TYR C CE1 1 
ATOM   6258 C CE2 . TYR C 1 228 ? 108.686 142.156 142.066 1.00 38.64  ? 302 TYR C CE2 1 
ATOM   6259 C CZ  . TYR C 1 228 ? 109.878 141.759 142.624 1.00 34.44  ? 302 TYR C CZ  1 
ATOM   6260 O OH  . TYR C 1 228 ? 110.470 142.530 143.597 1.00 38.14  ? 302 TYR C OH  1 
ATOM   6261 N N   . LEU C 1 229 ? 107.558 136.300 138.417 1.00 32.35  ? 303 LEU C N   1 
ATOM   6262 C CA  . LEU C 1 229 ? 106.562 135.520 137.691 1.00 25.98  ? 303 LEU C CA  1 
ATOM   6263 C C   . LEU C 1 229 ? 105.374 135.319 138.622 1.00 30.54  ? 303 LEU C C   1 
ATOM   6264 O O   . LEU C 1 229 ? 105.487 134.622 139.635 1.00 41.26  ? 303 LEU C O   1 
ATOM   6265 C CB  . LEU C 1 229 ? 107.140 134.186 137.214 1.00 35.19  ? 303 LEU C CB  1 
ATOM   6266 C CG  . LEU C 1 229 ? 106.305 133.302 136.281 1.00 37.86  ? 303 LEU C CG  1 
ATOM   6267 C CD1 . LEU C 1 229 ? 107.224 132.438 135.436 1.00 36.87  ? 303 LEU C CD1 1 
ATOM   6268 C CD2 . LEU C 1 229 ? 105.328 132.421 137.047 1.00 41.90  ? 303 LEU C CD2 1 
ATOM   6269 N N   . ASP C 1 230 ? 104.241 135.930 138.272 1.00 36.98  ? 304 ASP C N   1 
ATOM   6270 C CA  . ASP C 1 230 ? 103.029 135.889 139.092 1.00 34.31  ? 304 ASP C CA  1 
ATOM   6271 C C   . ASP C 1 230 ? 103.299 136.397 140.507 1.00 35.15  ? 304 ASP C C   1 
ATOM   6272 O O   . ASP C 1 230 ? 102.855 135.808 141.495 1.00 42.25  ? 304 ASP C O   1 
ATOM   6273 C CB  . ASP C 1 230 ? 102.426 134.483 139.121 1.00 42.09  ? 304 ASP C CB  1 
ATOM   6274 C CG  . ASP C 1 230 ? 101.440 134.249 137.994 1.00 45.15  ? 304 ASP C CG  1 
ATOM   6275 O OD1 . ASP C 1 230 ? 101.402 135.073 137.056 1.00 43.33  ? 304 ASP C OD1 1 
ATOM   6276 O OD2 . ASP C 1 230 ? 100.704 133.242 138.045 1.00 42.90  ? 304 ASP C OD2 1 
ATOM   6277 N N   . GLY C 1 231 ? 104.031 137.502 140.604 1.00 35.59  ? 305 GLY C N   1 
ATOM   6278 C CA  . GLY C 1 231 ? 104.357 138.087 141.893 1.00 33.59  ? 305 GLY C CA  1 
ATOM   6279 C C   . GLY C 1 231 ? 105.266 137.237 142.753 1.00 27.79  ? 305 GLY C C   1 
ATOM   6280 O O   . GLY C 1 231 ? 105.049 137.139 143.967 1.00 36.70  ? 305 GLY C O   1 
ATOM   6281 N N   . HIS C 1 232 ? 106.281 136.620 142.156 1.00 33.33  ? 306 HIS C N   1 
ATOM   6282 C CA  . HIS C 1 232 ? 107.203 135.759 142.881 1.00 27.99  ? 306 HIS C CA  1 
ATOM   6283 C C   . HIS C 1 232 ? 108.601 135.915 142.307 1.00 34.73  ? 306 HIS C C   1 
ATOM   6284 O O   . HIS C 1 232 ? 108.784 135.886 141.087 1.00 42.35  ? 306 HIS C O   1 
ATOM   6285 C CB  . HIS C 1 232 ? 106.775 134.288 142.802 1.00 36.21  ? 306 HIS C CB  1 
ATOM   6286 C CG  . HIS C 1 232 ? 105.639 133.937 143.711 1.00 41.35  ? 306 HIS C CG  1 
ATOM   6287 N ND1 . HIS C 1 232 ? 105.199 134.775 144.712 1.00 47.12  ? 306 HIS C ND1 1 
ATOM   6288 C CD2 . HIS C 1 232 ? 104.850 132.838 143.767 1.00 38.29  ? 306 HIS C CD2 1 
ATOM   6289 C CE1 . HIS C 1 232 ? 104.189 134.207 145.347 1.00 42.09  ? 306 HIS C CE1 1 
ATOM   6290 N NE2 . HIS C 1 232 ? 103.957 133.031 144.792 1.00 42.38  ? 306 HIS C NE2 1 
ATOM   6291 N N   . LEU C 1 233 ? 109.584 136.072 143.190 1.00 28.24  ? 307 LEU C N   1 
ATOM   6292 C CA  . LEU C 1 233 ? 110.982 136.094 142.774 1.00 23.96  ? 307 LEU C CA  1 
ATOM   6293 C C   . LEU C 1 233 ? 111.357 134.739 142.194 1.00 29.64  ? 307 LEU C C   1 
ATOM   6294 O O   . LEU C 1 233 ? 111.513 133.761 142.933 1.00 45.15  ? 307 LEU C O   1 
ATOM   6295 C CB  . LEU C 1 233 ? 111.886 136.440 143.953 1.00 35.76  ? 307 LEU C CB  1 
ATOM   6296 C CG  . LEU C 1 233 ? 113.204 137.160 143.648 1.00 37.18  ? 307 LEU C CG  1 
ATOM   6297 C CD1 . LEU C 1 233 ? 112.979 138.570 143.164 1.00 33.02  ? 307 LEU C CD1 1 
ATOM   6298 C CD2 . LEU C 1 233 ? 114.110 137.152 144.872 1.00 40.00  ? 307 LEU C CD2 1 
ATOM   6299 N N   . ILE C 1 234 ? 111.503 134.672 140.875 1.00 25.19  ? 308 ILE C N   1 
ATOM   6300 C CA  . ILE C 1 234 ? 112.003 133.451 140.257 1.00 27.58  ? 308 ILE C CA  1 
ATOM   6301 C C   . ILE C 1 234 ? 113.515 133.500 140.101 1.00 33.81  ? 308 ILE C C   1 
ATOM   6302 O O   . ILE C 1 234 ? 114.201 132.518 140.393 1.00 41.97  ? 308 ILE C O   1 
ATOM   6303 C CB  . ILE C 1 234 ? 111.300 133.192 138.910 1.00 27.23  ? 308 ILE C CB  1 
ATOM   6304 C CG1 . ILE C 1 234 ? 111.164 134.481 138.105 1.00 39.65  ? 308 ILE C CG1 1 
ATOM   6305 C CG2 . ILE C 1 234 ? 109.932 132.577 139.144 1.00 35.63  ? 308 ILE C CG2 1 
ATOM   6306 C CD1 . ILE C 1 234 ? 110.721 134.255 136.677 1.00 37.49  ? 308 ILE C CD1 1 
ATOM   6307 N N   . THR C 1 235 ? 114.060 134.633 139.658 1.00 28.91  ? 309 THR C N   1 
ATOM   6308 C CA  . THR C 1 235 ? 115.506 134.789 139.618 1.00 31.71  ? 309 THR C CA  1 
ATOM   6309 C C   . THR C 1 235 ? 115.882 136.256 139.460 1.00 25.88  ? 309 THR C C   1 
ATOM   6310 O O   . THR C 1 235 ? 115.051 137.116 139.136 1.00 40.78  ? 309 THR C O   1 
ATOM   6311 C CB  . THR C 1 235 ? 116.141 133.963 138.490 1.00 39.76  ? 309 THR C CB  1 
ATOM   6312 O OG1 . THR C 1 235 ? 117.567 133.974 138.637 1.00 46.77  ? 309 THR C OG1 1 
ATOM   6313 C CG2 . THR C 1 235 ? 115.782 134.535 137.132 1.00 36.75  ? 309 THR C CG2 1 
ATOM   6314 N N   . THR C 1 236 ? 117.156 136.520 139.736 1.00 27.12  ? 310 THR C N   1 
ATOM   6315 C CA  . THR C 1 236 ? 117.837 137.752 139.373 1.00 34.60  ? 310 THR C CA  1 
ATOM   6316 C C   . THR C 1 236 ? 118.920 137.385 138.370 1.00 33.05  ? 310 THR C C   1 
ATOM   6317 O O   . THR C 1 236 ? 119.670 136.427 138.586 1.00 36.37  ? 310 THR C O   1 
ATOM   6318 C CB  . THR C 1 236 ? 118.430 138.450 140.602 1.00 37.80  ? 310 THR C CB  1 
ATOM   6319 O OG1 . THR C 1 236 ? 119.108 139.648 140.201 1.00 37.41  ? 310 THR C OG1 1 
ATOM   6320 C CG2 . THR C 1 236 ? 119.387 137.539 141.369 1.00 39.81  ? 310 THR C CG2 1 
ATOM   6321 N N   . VAL C 1 237 ? 118.978 138.108 137.260 1.00 39.93  ? 311 VAL C N   1 
ATOM   6322 C CA  . VAL C 1 237 ? 119.947 137.815 136.214 1.00 38.17  ? 311 VAL C CA  1 
ATOM   6323 C C   . VAL C 1 237 ? 121.039 138.873 136.240 1.00 41.83  ? 311 VAL C C   1 
ATOM   6324 O O   . VAL C 1 237 ? 120.764 140.076 136.394 1.00 47.94  ? 311 VAL C O   1 
ATOM   6325 C CB  . VAL C 1 237 ? 119.284 137.706 134.830 1.00 41.21  ? 311 VAL C CB  1 
ATOM   6326 C CG1 . VAL C 1 237 ? 118.282 136.562 134.819 1.00 45.01  ? 311 VAL C CG1 1 
ATOM   6327 C CG2 . VAL C 1 237 ? 118.612 138.984 134.451 1.00 37.20  ? 311 VAL C CG2 1 
ATOM   6328 N N   . GLN C 1 238 ? 122.282 138.404 136.126 1.00 43.70  ? 312 GLN C N   1 
ATOM   6329 C CA  . GLN C 1 238 ? 123.495 139.208 136.195 1.00 43.31  ? 312 GLN C CA  1 
ATOM   6330 C C   . GLN C 1 238 ? 124.273 138.993 134.905 1.00 49.36  ? 312 GLN C C   1 
ATOM   6331 O O   . GLN C 1 238 ? 124.795 137.899 134.662 1.00 53.06  ? 312 GLN C O   1 
ATOM   6332 C CB  . GLN C 1 238 ? 124.336 138.819 137.410 1.00 46.58  ? 312 GLN C CB  1 
ATOM   6333 C CG  . GLN C 1 238 ? 125.579 139.664 137.609 1.00 50.56  ? 312 GLN C CG  1 
ATOM   6334 C CD  . GLN C 1 238 ? 126.348 139.280 138.857 1.00 57.75  ? 312 GLN C CD  1 
ATOM   6335 O OE1 . GLN C 1 238 ? 125.973 138.348 139.569 1.00 57.13  ? 312 GLN C OE1 1 
ATOM   6336 N NE2 . GLN C 1 238 ? 127.431 139.997 139.129 1.00 55.56  ? 312 GLN C NE2 1 
ATOM   6337 N N   . GLY C 1 239 ? 124.349 140.033 134.086 1.00 50.76  ? 313 GLY C N   1 
ATOM   6338 C CA  . GLY C 1 239 ? 125.035 139.957 132.813 1.00 41.79  ? 313 GLY C CA  1 
ATOM   6339 C C   . GLY C 1 239 ? 124.620 141.071 131.878 1.00 45.93  ? 313 GLY C C   1 
ATOM   6340 O O   . GLY C 1 239 ? 124.492 142.223 132.301 1.00 54.20  ? 313 GLY C O   1 
ATOM   6341 N N   . ASP C 1 240 ? 124.403 140.751 130.604 1.00 36.51  ? 314 ASP C N   1 
ATOM   6342 C CA  . ASP C 1 240 ? 123.949 141.778 129.677 1.00 35.84  ? 314 ASP C CA  1 
ATOM   6343 C C   . ASP C 1 240 ? 122.449 142.014 129.814 1.00 38.14  ? 314 ASP C C   1 
ATOM   6344 O O   . ASP C 1 240 ? 122.005 143.159 129.934 1.00 48.61  ? 314 ASP C O   1 
ATOM   6345 C CB  . ASP C 1 240 ? 124.313 141.394 128.244 1.00 41.49  ? 314 ASP C CB  1 
ATOM   6346 C CG  . ASP C 1 240 ? 125.810 141.277 128.035 1.00 44.84  ? 314 ASP C CG  1 
ATOM   6347 O OD1 . ASP C 1 240 ? 126.544 141.171 129.040 1.00 45.96  ? 314 ASP C OD1 1 
ATOM   6348 O OD2 . ASP C 1 240 ? 126.253 141.288 126.868 1.00 45.94  ? 314 ASP C OD2 1 
ATOM   6349 N N   . GLY C 1 241 ? 121.657 140.946 129.821 1.00 29.52  ? 315 GLY C N   1 
ATOM   6350 C CA  . GLY C 1 241 ? 120.224 141.091 130.002 1.00 28.83  ? 315 GLY C CA  1 
ATOM   6351 C C   . GLY C 1 241 ? 119.493 139.814 129.638 1.00 29.53  ? 315 GLY C C   1 
ATOM   6352 O O   . GLY C 1 241 ? 120.102 138.750 129.518 1.00 39.15  ? 315 GLY C O   1 
ATOM   6353 N N   . VAL C 1 242 ? 118.173 139.939 129.467 1.00 24.37  ? 316 VAL C N   1 
ATOM   6354 C CA  . VAL C 1 242 ? 117.323 138.822 129.078 1.00 27.78  ? 316 VAL C CA  1 
ATOM   6355 C C   . VAL C 1 242 ? 116.472 139.225 127.879 1.00 32.09  ? 316 VAL C C   1 
ATOM   6356 O O   . VAL C 1 242 ? 116.237 140.406 127.618 1.00 36.87  ? 316 VAL C O   1 
ATOM   6357 C CB  . VAL C 1 242 ? 116.427 138.321 130.234 1.00 31.65  ? 316 VAL C CB  1 
ATOM   6358 C CG1 . VAL C 1 242 ? 117.277 137.741 131.349 1.00 36.53  ? 316 VAL C CG1 1 
ATOM   6359 C CG2 . VAL C 1 242 ? 115.549 139.436 130.755 1.00 26.61  ? 316 VAL C CG2 1 
ATOM   6360 N N   . ILE C 1 243 ? 116.009 138.210 127.148 1.00 32.48  ? 317 ILE C N   1 
ATOM   6361 C CA  . ILE C 1 243 ? 115.408 138.382 125.827 1.00 26.71  ? 317 ILE C CA  1 
ATOM   6362 C C   . ILE C 1 243 ? 113.990 137.821 125.810 1.00 35.58  ? 317 ILE C C   1 
ATOM   6363 O O   . ILE C 1 243 ? 113.601 137.147 124.850 1.00 47.74  ? 317 ILE C O   1 
ATOM   6364 C CB  . ILE C 1 243 ? 116.264 137.720 124.730 1.00 25.30  ? 317 ILE C CB  1 
ATOM   6365 C CG1 . ILE C 1 243 ? 117.739 138.021 124.937 1.00 30.22  ? 317 ILE C CG1 1 
ATOM   6366 C CG2 . ILE C 1 243 ? 115.899 138.255 123.355 1.00 33.04  ? 317 ILE C CG2 1 
ATOM   6367 C CD1 . ILE C 1 243 ? 118.644 137.164 124.085 1.00 35.16  ? 317 ILE C CD1 1 
ATOM   6368 N N   . VAL C 1 244 ? 113.238 138.015 126.897 1.00 25.73  ? 318 VAL C N   1 
ATOM   6369 C CA  . VAL C 1 244 ? 111.867 137.509 126.994 1.00 31.98  ? 318 VAL C CA  1 
ATOM   6370 C C   . VAL C 1 244 ? 111.119 137.759 125.687 1.00 31.10  ? 318 VAL C C   1 
ATOM   6371 O O   . VAL C 1 244 ? 111.067 138.889 125.189 1.00 36.38  ? 318 VAL C O   1 
ATOM   6372 C CB  . VAL C 1 244 ? 111.134 138.133 128.199 1.00 29.96  ? 318 VAL C CB  1 
ATOM   6373 C CG1 . VAL C 1 244 ? 111.138 139.652 128.116 1.00 31.19  ? 318 VAL C CG1 1 
ATOM   6374 C CG2 . VAL C 1 244 ? 109.707 137.617 128.273 1.00 33.17  ? 318 VAL C CG2 1 
ATOM   6375 N N   . SER C 1 245 ? 110.551 136.698 125.114 1.00 29.36  ? 319 SER C N   1 
ATOM   6376 C CA  . SER C 1 245 ? 110.194 136.705 123.702 1.00 22.39  ? 319 SER C CA  1 
ATOM   6377 C C   . SER C 1 245 ? 108.957 135.857 123.451 1.00 32.38  ? 319 SER C C   1 
ATOM   6378 O O   . SER C 1 245 ? 108.448 135.169 124.339 1.00 35.27  ? 319 SER C O   1 
ATOM   6379 C CB  . SER C 1 245 ? 111.350 136.189 122.839 1.00 27.18  ? 319 SER C CB  1 
ATOM   6380 O OG  . SER C 1 245 ? 111.419 134.774 122.872 1.00 35.45  ? 319 SER C OG  1 
ATOM   6381 N N   . THR C 1 246 ? 108.486 135.921 122.215 1.00 29.47  ? 320 THR C N   1 
ATOM   6382 C CA  . THR C 1 246 ? 107.427 135.090 121.668 1.00 22.21  ? 320 THR C CA  1 
ATOM   6383 C C   . THR C 1 246 ? 108.025 133.896 120.942 1.00 32.43  ? 320 THR C C   1 
ATOM   6384 O O   . THR C 1 246 ? 109.235 133.835 120.706 1.00 37.05  ? 320 THR C O   1 
ATOM   6385 C CB  . THR C 1 246 ? 106.565 135.911 120.704 1.00 25.65  ? 320 THR C CB  1 
ATOM   6386 O OG1 . THR C 1 246 ? 107.374 136.383 119.620 1.00 35.21  ? 320 THR C OG1 1 
ATOM   6387 C CG2 . THR C 1 246 ? 105.944 137.094 121.412 1.00 26.47  ? 320 THR C CG2 1 
ATOM   6388 N N   . PRO C 1 247 ? 107.203 132.903 120.582 1.00 24.76  ? 321 PRO C N   1 
ATOM   6389 C CA  . PRO C 1 247 ? 107.706 131.852 119.682 1.00 18.89  ? 321 PRO C CA  1 
ATOM   6390 C C   . PRO C 1 247 ? 108.224 132.397 118.363 1.00 25.63  ? 321 PRO C C   1 
ATOM   6391 O O   . PRO C 1 247 ? 109.208 131.875 117.825 1.00 30.19  ? 321 PRO C O   1 
ATOM   6392 C CB  . PRO C 1 247 ? 106.482 130.949 119.492 1.00 22.16  ? 321 PRO C CB  1 
ATOM   6393 C CG  . PRO C 1 247 ? 105.709 131.124 120.744 1.00 23.26  ? 321 PRO C CG  1 
ATOM   6394 C CD  . PRO C 1 247 ? 105.877 132.564 121.128 1.00 26.73  ? 321 PRO C CD  1 
ATOM   6395 N N   . THR C 1 248 ? 107.588 133.445 117.830 1.00 31.63  ? 322 THR C N   1 
ATOM   6396 C CA  . THR C 1 248 ? 108.092 134.087 116.620 1.00 24.84  ? 322 THR C CA  1 
ATOM   6397 C C   . THR C 1 248 ? 109.503 134.620 116.832 1.00 29.10  ? 322 THR C C   1 
ATOM   6398 O O   . THR C 1 248 ? 110.342 134.565 115.925 1.00 39.87  ? 322 THR C O   1 
ATOM   6399 C CB  . THR C 1 248 ? 107.150 135.214 116.193 1.00 26.20  ? 322 THR C CB  1 
ATOM   6400 O OG1 . THR C 1 248 ? 105.848 134.675 115.932 1.00 32.08  ? 322 THR C OG1 1 
ATOM   6401 C CG2 . THR C 1 248 ? 107.664 135.905 114.939 1.00 30.09  ? 322 THR C CG2 1 
ATOM   6402 N N   . GLY C 1 249 ? 109.788 135.124 118.028 1.00 20.91  ? 323 GLY C N   1 
ATOM   6403 C CA  . GLY C 1 249 ? 111.118 135.566 118.381 1.00 24.24  ? 323 GLY C CA  1 
ATOM   6404 C C   . GLY C 1 249 ? 112.059 134.471 118.818 1.00 27.18  ? 323 GLY C C   1 
ATOM   6405 O O   . GLY C 1 249 ? 113.194 134.762 119.204 1.00 33.93  ? 323 GLY C O   1 
ATOM   6406 N N   . SER C 1 250 ? 111.614 133.212 118.776 1.00 31.69  ? 324 SER C N   1 
ATOM   6407 C CA  . SER C 1 250 ? 112.482 132.103 119.161 1.00 27.51  ? 324 SER C CA  1 
ATOM   6408 C C   . SER C 1 250 ? 113.681 131.979 118.232 1.00 28.78  ? 324 SER C C   1 
ATOM   6409 O O   . SER C 1 250 ? 114.768 131.593 118.673 1.00 40.19  ? 324 SER C O   1 
ATOM   6410 C CB  . SER C 1 250 ? 111.689 130.797 119.172 1.00 33.82  ? 324 SER C CB  1 
ATOM   6411 O OG  . SER C 1 250 ? 111.265 130.449 117.865 1.00 36.74  ? 324 SER C OG  1 
ATOM   6412 N N   . THR C 1 251 ? 113.504 132.296 116.952 1.00 34.89  ? 325 THR C N   1 
ATOM   6413 C CA  . THR C 1 251 ? 114.582 132.276 115.974 1.00 34.49  ? 325 THR C CA  1 
ATOM   6414 C C   . THR C 1 251 ? 115.258 133.633 115.827 1.00 31.40  ? 325 THR C C   1 
ATOM   6415 O O   . THR C 1 251 ? 116.169 133.775 115.005 1.00 34.50  ? 325 THR C O   1 
ATOM   6416 C CB  . THR C 1 251 ? 114.048 131.810 114.618 1.00 29.35  ? 325 THR C CB  1 
ATOM   6417 O OG1 . THR C 1 251 ? 113.134 132.785 114.104 1.00 39.63  ? 325 THR C OG1 1 
ATOM   6418 C CG2 . THR C 1 251 ? 113.317 130.489 114.767 1.00 29.05  ? 325 THR C CG2 1 
ATOM   6419 N N   . ALA C 1 252 ? 114.830 134.618 116.603 1.00 33.47  ? 326 ALA C N   1 
ATOM   6420 C CA  . ALA C 1 252 ? 115.381 135.965 116.609 1.00 30.41  ? 326 ALA C CA  1 
ATOM   6421 C C   . ALA C 1 252 ? 116.538 136.028 117.608 1.00 34.36  ? 326 ALA C C   1 
ATOM   6422 O O   . ALA C 1 252 ? 117.117 135.000 117.969 1.00 41.28  ? 326 ALA C O   1 
ATOM   6423 C CB  . ALA C 1 252 ? 114.276 136.980 116.915 1.00 36.42  ? 326 ALA C CB  1 
ATOM   6424 N N   . TYR C 1 253 ? 116.901 137.238 118.036 1.00 31.61  ? 327 TYR C N   1 
ATOM   6425 C CA  . TYR C 1 253 ? 117.977 137.506 118.988 1.00 23.70  ? 327 TYR C CA  1 
ATOM   6426 C C   . TYR C 1 253 ? 117.980 136.547 120.174 1.00 28.71  ? 327 TYR C C   1 
ATOM   6427 O O   . TYR C 1 253 ? 119.026 136.326 120.793 1.00 38.62  ? 327 TYR C O   1 
ATOM   6428 C CB  . TYR C 1 253 ? 117.859 138.955 119.469 1.00 31.76  ? 327 TYR C CB  1 
ATOM   6429 C CG  . TYR C 1 253 ? 118.895 139.416 120.469 1.00 30.40  ? 327 TYR C CG  1 
ATOM   6430 C CD1 . TYR C 1 253 ? 120.235 139.487 120.127 1.00 37.44  ? 327 TYR C CD1 1 
ATOM   6431 C CD2 . TYR C 1 253 ? 118.521 139.849 121.732 1.00 33.47  ? 327 TYR C CD2 1 
ATOM   6432 C CE1 . TYR C 1 253 ? 121.180 139.929 121.026 1.00 35.16  ? 327 TYR C CE1 1 
ATOM   6433 C CE2 . TYR C 1 253 ? 119.460 140.296 122.639 1.00 34.65  ? 327 TYR C CE2 1 
ATOM   6434 C CZ  . TYR C 1 253 ? 120.788 140.333 122.279 1.00 38.07  ? 327 TYR C CZ  1 
ATOM   6435 O OH  . TYR C 1 253 ? 121.731 140.778 123.173 1.00 43.34  ? 327 TYR C OH  1 
ATOM   6436 N N   . ALA C 1 254 ? 116.819 135.977 120.504 1.00 31.57  ? 328 ALA C N   1 
ATOM   6437 C CA  . ALA C 1 254 ? 116.781 134.906 121.495 1.00 28.11  ? 328 ALA C CA  1 
ATOM   6438 C C   . ALA C 1 254 ? 117.592 133.701 121.034 1.00 31.51  ? 328 ALA C C   1 
ATOM   6439 O O   . ALA C 1 254 ? 118.336 133.107 121.823 1.00 36.95  ? 328 ALA C O   1 
ATOM   6440 C CB  . ALA C 1 254 ? 115.334 134.504 121.777 1.00 35.30  ? 328 ALA C CB  1 
ATOM   6441 N N   . ALA C 1 255 ? 117.467 133.328 119.757 1.00 32.52  ? 329 ALA C N   1 
ATOM   6442 C CA  . ALA C 1 255 ? 118.242 132.208 119.229 1.00 20.70  ? 329 ALA C CA  1 
ATOM   6443 C C   . ALA C 1 255 ? 119.734 132.500 119.244 1.00 31.04  ? 329 ALA C C   1 
ATOM   6444 O O   . ALA C 1 255 ? 120.545 131.577 119.369 1.00 38.37  ? 329 ALA C O   1 
ATOM   6445 C CB  . ALA C 1 255 ? 117.792 131.873 117.809 1.00 27.09  ? 329 ALA C CB  1 
ATOM   6446 N N   . ALA C 1 256 ? 120.115 133.771 119.107 1.00 33.96  ? 330 ALA C N   1 
ATOM   6447 C CA  . ALA C 1 256 ? 121.529 134.124 119.132 1.00 22.43  ? 330 ALA C CA  1 
ATOM   6448 C C   . ALA C 1 256 ? 122.164 133.802 120.477 1.00 26.16  ? 330 ALA C C   1 
ATOM   6449 O O   . ALA C 1 256 ? 123.358 133.491 120.542 1.00 33.90  ? 330 ALA C O   1 
ATOM   6450 C CB  . ALA C 1 256 ? 121.702 135.605 118.801 1.00 28.68  ? 330 ALA C CB  1 
ATOM   6451 N N   . ALA C 1 257 ? 121.383 133.849 121.553 1.00 32.35  ? 331 ALA C N   1 
ATOM   6452 C CA  . ALA C 1 257 ? 121.895 133.639 122.899 1.00 34.90  ? 331 ALA C CA  1 
ATOM   6453 C C   . ALA C 1 257 ? 121.806 132.190 123.356 1.00 32.98  ? 331 ALA C C   1 
ATOM   6454 O O   . ALA C 1 257 ? 122.167 131.896 124.500 1.00 37.39  ? 331 ALA C O   1 
ATOM   6455 C CB  . ALA C 1 257 ? 121.146 134.534 123.888 1.00 34.11  ? 331 ALA C CB  1 
ATOM   6456 N N   . GLY C 1 258 ? 121.343 131.283 122.501 1.00 29.28  ? 332 GLY C N   1 
ATOM   6457 C CA  . GLY C 1 258 ? 121.274 129.876 122.834 1.00 31.53  ? 332 GLY C CA  1 
ATOM   6458 C C   . GLY C 1 258 ? 119.887 129.321 123.071 1.00 33.23  ? 332 GLY C C   1 
ATOM   6459 O O   . GLY C 1 258 ? 119.769 128.176 123.521 1.00 37.51  ? 332 GLY C O   1 
ATOM   6460 N N   . ALA C 1 259 ? 118.838 130.085 122.787 1.00 34.76  ? 333 ALA C N   1 
ATOM   6461 C CA  . ALA C 1 259 ? 117.483 129.596 122.987 1.00 31.26  ? 333 ALA C CA  1 
ATOM   6462 C C   . ALA C 1 259 ? 117.128 128.538 121.947 1.00 36.14  ? 333 ALA C C   1 
ATOM   6463 O O   . ALA C 1 259 ? 117.713 128.476 120.862 1.00 42.58  ? 333 ALA C O   1 
ATOM   6464 C CB  . ALA C 1 259 ? 116.488 130.751 122.925 1.00 37.34  ? 333 ALA C CB  1 
ATOM   6465 N N   . SER C 1 260 ? 116.157 127.696 122.293 1.00 35.49  ? 334 SER C N   1 
ATOM   6466 C CA  . SER C 1 260 ? 115.725 126.620 121.416 1.00 28.93  ? 334 SER C CA  1 
ATOM   6467 C C   . SER C 1 260 ? 114.815 127.159 120.313 1.00 36.94  ? 334 SER C C   1 
ATOM   6468 O O   . SER C 1 260 ? 114.517 128.354 120.237 1.00 40.77  ? 334 SER C O   1 
ATOM   6469 C CB  . SER C 1 260 ? 115.018 125.533 122.220 1.00 31.25  ? 334 SER C CB  1 
ATOM   6470 O OG  . SER C 1 260 ? 115.775 125.169 123.359 1.00 41.17  ? 334 SER C OG  1 
ATOM   6471 N N   . MET C 1 261 ? 114.367 126.257 119.445 1.00 42.07  ? 335 MET C N   1 
ATOM   6472 C CA  . MET C 1 261 ? 113.484 126.592 118.335 1.00 30.65  ? 335 MET C CA  1 
ATOM   6473 C C   . MET C 1 261 ? 112.059 126.217 118.722 1.00 35.15  ? 335 MET C C   1 
ATOM   6474 O O   . MET C 1 261 ? 111.782 125.048 119.012 1.00 35.97  ? 335 MET C O   1 
ATOM   6475 C CB  . MET C 1 261 ? 113.905 125.849 117.067 1.00 37.97  ? 335 MET C CB  1 
ATOM   6476 C CG  . MET C 1 261 ? 115.272 126.230 116.512 1.00 36.72  ? 335 MET C CG  1 
ATOM   6477 S SD  . MET C 1 261 ? 115.436 127.950 116.013 1.00 57.72  ? 335 MET C SD  1 
ATOM   6478 C CE  . MET C 1 261 ? 116.348 128.617 117.399 1.00 35.57  ? 335 MET C CE  1 
ATOM   6479 N N   . ILE C 1 262 ? 111.159 127.196 118.731 1.00 37.59  ? 336 ILE C N   1 
ATOM   6480 C CA  . ILE C 1 262 ? 109.763 126.971 119.087 1.00 33.03  ? 336 ILE C CA  1 
ATOM   6481 C C   . ILE C 1 262 ? 108.879 127.372 117.915 1.00 32.86  ? 336 ILE C C   1 
ATOM   6482 O O   . ILE C 1 262 ? 108.991 128.489 117.396 1.00 39.95  ? 336 ILE C O   1 
ATOM   6483 C CB  . ILE C 1 262 ? 109.365 127.733 120.365 1.00 29.89  ? 336 ILE C CB  1 
ATOM   6484 C CG1 . ILE C 1 262 ? 110.350 127.424 121.493 1.00 36.20  ? 336 ILE C CG1 1 
ATOM   6485 C CG2 . ILE C 1 262 ? 107.953 127.374 120.780 1.00 32.12  ? 336 ILE C CG2 1 
ATOM   6486 C CD1 . ILE C 1 262 ? 110.008 128.087 122.804 1.00 37.72  ? 336 ILE C CD1 1 
ATOM   6487 N N   . HIS C 1 263 ? 108.008 126.455 117.501 1.00 29.61  ? 337 HIS C N   1 
ATOM   6488 C CA  . HIS C 1 263 ? 107.068 126.726 116.424 1.00 23.07  ? 337 HIS C CA  1 
ATOM   6489 C C   . HIS C 1 263 ? 106.078 127.806 116.854 1.00 31.28  ? 337 HIS C C   1 
ATOM   6490 O O   . HIS C 1 263 ? 105.650 127.831 118.013 1.00 41.60  ? 337 HIS C O   1 
ATOM   6491 C CB  . HIS C 1 263 ? 106.330 125.439 116.048 1.00 24.74  ? 337 HIS C CB  1 
ATOM   6492 C CG  . HIS C 1 263 ? 105.594 125.509 114.745 1.00 24.69  ? 337 HIS C CG  1 
ATOM   6493 N ND1 . HIS C 1 263 ? 104.436 126.238 114.581 1.00 35.29  ? 337 HIS C ND1 1 
ATOM   6494 C CD2 . HIS C 1 263 ? 105.850 124.936 113.546 1.00 24.16  ? 337 HIS C CD2 1 
ATOM   6495 C CE1 . HIS C 1 263 ? 104.012 126.114 113.336 1.00 31.68  ? 337 HIS C CE1 1 
ATOM   6496 N NE2 . HIS C 1 263 ? 104.853 125.328 112.687 1.00 33.70  ? 337 HIS C NE2 1 
ATOM   6497 N N   . PRO C 1 264 ? 105.693 128.717 115.947 1.00 28.17  ? 338 PRO C N   1 
ATOM   6498 C CA  . PRO C 1 264 ? 104.778 129.804 116.328 1.00 20.40  ? 338 PRO C CA  1 
ATOM   6499 C C   . PRO C 1 264 ? 103.389 129.338 116.739 1.00 23.12  ? 338 PRO C C   1 
ATOM   6500 O O   . PRO C 1 264 ? 102.553 130.157 117.133 1.00 36.17  ? 338 PRO C O   1 
ATOM   6501 C CB  . PRO C 1 264 ? 104.721 130.667 115.059 1.00 22.52  ? 338 PRO C CB  1 
ATOM   6502 C CG  . PRO C 1 264 ? 105.158 129.758 113.959 1.00 21.15  ? 338 PRO C CG  1 
ATOM   6503 C CD  . PRO C 1 264 ? 106.207 128.899 114.581 1.00 33.21  ? 338 PRO C CD  1 
ATOM   6504 N N   . ASN C 1 265 ? 103.126 128.036 116.655 1.00 20.03  ? 339 ASN C N   1 
ATOM   6505 C CA  . ASN C 1 265 ? 101.853 127.467 117.073 1.00 24.58  ? 339 ASN C CA  1 
ATOM   6506 C C   . ASN C 1 265 ? 101.891 126.928 118.498 1.00 29.57  ? 339 ASN C C   1 
ATOM   6507 O O   . ASN C 1 265 ? 100.908 126.333 118.951 1.00 31.57  ? 339 ASN C O   1 
ATOM   6508 C CB  . ASN C 1 265 ? 101.427 126.360 116.106 1.00 29.55  ? 339 ASN C CB  1 
ATOM   6509 C CG  . ASN C 1 265 ? 100.506 126.864 115.013 1.00 30.19  ? 339 ASN C CG  1 
ATOM   6510 O OD1 . ASN C 1 265 ? 100.141 128.038 114.985 1.00 35.73  ? 339 ASN C OD1 1 
ATOM   6511 N ND2 . ASN C 1 265 ? 100.126 125.974 114.105 1.00 31.28  ? 339 ASN C ND2 1 
ATOM   6512 N N   . VAL C 1 266 ? 102.996 127.121 119.212 1.00 33.68  ? 340 VAL C N   1 
ATOM   6513 C CA  . VAL C 1 266 ? 103.141 126.659 120.590 1.00 22.80  ? 340 VAL C CA  1 
ATOM   6514 C C   . VAL C 1 266 ? 102.870 127.848 121.508 1.00 31.69  ? 340 VAL C C   1 
ATOM   6515 O O   . VAL C 1 266 ? 103.654 128.812 121.502 1.00 38.66  ? 340 VAL C O   1 
ATOM   6516 C CB  . VAL C 1 266 ? 104.532 126.066 120.844 1.00 17.44  ? 340 VAL C CB  1 
ATOM   6517 C CG1 . VAL C 1 266 ? 104.602 125.452 122.230 1.00 26.81  ? 340 VAL C CG1 1 
ATOM   6518 C CG2 . VAL C 1 266 ? 104.869 125.034 119.781 1.00 22.83  ? 340 VAL C CG2 1 
ATOM   6519 N N   . PRO C 1 267 ? 101.797 127.833 122.300 1.00 28.89  ? 341 PRO C N   1 
ATOM   6520 C CA  . PRO C 1 267 ? 101.428 128.974 123.171 1.00 30.58  ? 341 PRO C CA  1 
ATOM   6521 C C   . PRO C 1 267 ? 102.266 129.088 124.444 1.00 28.67  ? 341 PRO C C   1 
ATOM   6522 O O   . PRO C 1 267 ? 101.912 128.612 125.522 1.00 32.44  ? 341 PRO C O   1 
ATOM   6523 C CB  . PRO C 1 267 ? 99.960  128.686 123.489 1.00 28.57  ? 341 PRO C CB  1 
ATOM   6524 C CG  . PRO C 1 267 ? 99.867  127.199 123.439 1.00 25.66  ? 341 PRO C CG  1 
ATOM   6525 C CD  . PRO C 1 267 ? 100.770 126.777 122.316 1.00 24.05  ? 341 PRO C CD  1 
ATOM   6526 N N   . ALA C 1 268 ? 103.423 129.737 124.330 1.00 22.03  ? 342 ALA C N   1 
ATOM   6527 C CA  . ALA C 1 268 ? 104.304 129.890 125.478 1.00 16.98  ? 342 ALA C CA  1 
ATOM   6528 C C   . ALA C 1 268 ? 105.137 131.156 125.338 1.00 25.04  ? 342 ALA C C   1 
ATOM   6529 O O   . ALA C 1 268 ? 105.289 131.709 124.246 1.00 35.90  ? 342 ALA C O   1 
ATOM   6530 C CB  . ALA C 1 268 ? 105.215 128.672 125.648 1.00 27.25  ? 342 ALA C CB  1 
ATOM   6531 N N   . ILE C 1 269 ? 105.675 131.607 126.470 1.00 25.92  ? 343 ILE C N   1 
ATOM   6532 C CA  . ILE C 1 269 ? 106.577 132.750 126.533 1.00 19.30  ? 343 ILE C CA  1 
ATOM   6533 C C   . ILE C 1 269 ? 107.971 132.235 126.862 1.00 29.07  ? 343 ILE C C   1 
ATOM   6534 O O   . ILE C 1 269 ? 108.134 131.226 127.555 1.00 32.31  ? 343 ILE C O   1 
ATOM   6535 C CB  . ILE C 1 269 ? 106.110 133.790 127.575 1.00 19.43  ? 343 ILE C CB  1 
ATOM   6536 C CG1 . ILE C 1 269 ? 104.629 134.118 127.381 1.00 29.18  ? 343 ILE C CG1 1 
ATOM   6537 C CG2 . ILE C 1 269 ? 106.936 135.063 127.485 1.00 26.24  ? 343 ILE C CG2 1 
ATOM   6538 C CD1 . ILE C 1 269 ? 104.097 135.130 128.373 1.00 30.19  ? 343 ILE C CD1 1 
ATOM   6539 N N   . MET C 1 270 ? 108.985 132.922 126.349 1.00 32.85  ? 344 MET C N   1 
ATOM   6540 C CA  . MET C 1 270 ? 110.368 132.505 126.511 1.00 23.38  ? 344 MET C CA  1 
ATOM   6541 C C   . MET C 1 270 ? 111.105 133.460 127.439 1.00 30.02  ? 344 MET C C   1 
ATOM   6542 O O   . MET C 1 270 ? 110.746 134.634 127.554 1.00 41.88  ? 344 MET C O   1 
ATOM   6543 C CB  . MET C 1 270 ? 111.069 132.452 125.156 1.00 33.24  ? 344 MET C CB  1 
ATOM   6544 C CG  . MET C 1 270 ? 110.521 131.379 124.245 1.00 40.82  ? 344 MET C CG  1 
ATOM   6545 S SD  . MET C 1 270 ? 111.306 131.398 122.631 1.00 62.83  ? 344 MET C SD  1 
ATOM   6546 C CE  . MET C 1 270 ? 112.928 130.797 123.069 1.00 38.40  ? 344 MET C CE  1 
ATOM   6547 N N   . ILE C 1 271 ? 112.131 132.944 128.117 1.00 27.83  ? 345 ILE C N   1 
ATOM   6548 C CA  . ILE C 1 271 ? 113.039 133.762 128.917 1.00 23.11  ? 345 ILE C CA  1 
ATOM   6549 C C   . ILE C 1 271 ? 114.446 133.230 128.677 1.00 29.51  ? 345 ILE C C   1 
ATOM   6550 O O   . ILE C 1 271 ? 114.791 132.146 129.160 1.00 34.52  ? 345 ILE C O   1 
ATOM   6551 C CB  . ILE C 1 271 ? 112.707 133.735 130.416 1.00 19.88  ? 345 ILE C CB  1 
ATOM   6552 C CG1 . ILE C 1 271 ? 111.303 134.279 130.681 1.00 24.49  ? 345 ILE C CG1 1 
ATOM   6553 C CG2 . ILE C 1 271 ? 113.734 134.534 131.203 1.00 29.76  ? 345 ILE C CG2 1 
ATOM   6554 C CD1 . ILE C 1 271 ? 110.815 134.015 132.086 1.00 32.05  ? 345 ILE C CD1 1 
ATOM   6555 N N   . THR C 1 272 ? 115.257 133.984 127.938 1.00 32.65  ? 346 THR C N   1 
ATOM   6556 C CA  . THR C 1 272 ? 116.630 133.591 127.672 1.00 29.89  ? 346 THR C CA  1 
ATOM   6557 C C   . THR C 1 272 ? 117.571 134.750 127.970 1.00 26.13  ? 346 THR C C   1 
ATOM   6558 O O   . THR C 1 272 ? 117.221 135.915 127.743 1.00 34.08  ? 346 THR C O   1 
ATOM   6559 C CB  . THR C 1 272 ? 116.795 133.115 126.215 1.00 28.65  ? 346 THR C CB  1 
ATOM   6560 O OG1 . THR C 1 272 ? 118.128 132.632 126.004 1.00 36.14  ? 346 THR C OG1 1 
ATOM   6561 C CG2 . THR C 1 272 ? 116.494 134.227 125.232 1.00 29.12  ? 346 THR C CG2 1 
ATOM   6562 N N   . PRO C 1 273 ? 118.766 134.466 128.498 1.00 29.21  ? 347 PRO C N   1 
ATOM   6563 C CA  . PRO C 1 273 ? 119.678 135.544 128.902 1.00 25.99  ? 347 PRO C CA  1 
ATOM   6564 C C   . PRO C 1 273 ? 120.454 136.151 127.749 1.00 29.16  ? 347 PRO C C   1 
ATOM   6565 O O   . PRO C 1 273 ? 120.220 135.823 126.583 1.00 39.21  ? 347 PRO C O   1 
ATOM   6566 C CB  . PRO C 1 273 ? 120.630 134.837 129.867 1.00 30.99  ? 347 PRO C CB  1 
ATOM   6567 C CG  . PRO C 1 273 ? 120.706 133.454 129.309 1.00 34.72  ? 347 PRO C CG  1 
ATOM   6568 C CD  . PRO C 1 273 ? 119.305 133.140 128.850 1.00 36.34  ? 347 PRO C CD  1 
ATOM   6569 N N   . ILE C 1 274 ? 121.382 137.047 128.078 1.00 28.24  ? 348 ILE C N   1 
ATOM   6570 C CA  . ILE C 1 274 ? 122.379 137.546 127.132 1.00 27.76  ? 348 ILE C CA  1 
ATOM   6571 C C   . ILE C 1 274 ? 123.726 137.398 127.834 1.00 38.15  ? 348 ILE C C   1 
ATOM   6572 O O   . ILE C 1 274 ? 124.157 138.290 128.572 1.00 46.91  ? 348 ILE C O   1 
ATOM   6573 C CB  . ILE C 1 274 ? 122.137 138.998 126.715 1.00 33.01  ? 348 ILE C CB  1 
ATOM   6574 C CG1 . ILE C 1 274 ? 120.711 139.191 126.217 1.00 28.94  ? 348 ILE C CG1 1 
ATOM   6575 C CG2 . ILE C 1 274 ? 123.114 139.388 125.621 1.00 37.26  ? 348 ILE C CG2 1 
ATOM   6576 C CD1 . ILE C 1 274 ? 120.293 140.640 126.111 1.00 35.97  ? 348 ILE C CD1 1 
ATOM   6577 N N   . CYS C 1 275 ? 124.397 136.271 127.607 1.00 31.95  ? 349 CYS C N   1 
ATOM   6578 C CA  . CYS C 1 275 ? 125.702 135.987 128.193 1.00 30.08  ? 349 CYS C CA  1 
ATOM   6579 C C   . CYS C 1 275 ? 125.695 136.201 129.703 1.00 32.45  ? 349 CYS C C   1 
ATOM   6580 O O   . CYS C 1 275 ? 126.315 137.151 130.196 1.00 39.74  ? 349 CYS C O   1 
ATOM   6581 C CB  . CYS C 1 275 ? 126.779 136.859 127.544 1.00 34.38  ? 349 CYS C CB  1 
ATOM   6582 S SG  . CYS C 1 275 ? 126.612 137.039 125.756 1.00 46.26  ? 349 CYS C SG  1 
ATOM   6583 N N   . PRO C 1 276 ? 125.009 135.356 130.467 1.00 30.11  ? 350 PRO C N   1 
ATOM   6584 C CA  . PRO C 1 276 ? 124.999 135.524 131.921 1.00 29.88  ? 350 PRO C CA  1 
ATOM   6585 C C   . PRO C 1 276 ? 126.271 134.991 132.556 1.00 36.33  ? 350 PRO C C   1 
ATOM   6586 O O   . PRO C 1 276 ? 126.887 134.038 132.074 1.00 41.02  ? 350 PRO C O   1 
ATOM   6587 C CB  . PRO C 1 276 ? 123.782 134.702 132.354 1.00 33.97  ? 350 PRO C CB  1 
ATOM   6588 C CG  . PRO C 1 276 ? 123.727 133.603 131.355 1.00 33.38  ? 350 PRO C CG  1 
ATOM   6589 C CD  . PRO C 1 276 ? 124.246 134.167 130.049 1.00 33.30  ? 350 PRO C CD  1 
ATOM   6590 N N   . HIS C 1 277 ? 126.656 135.617 133.667 1.00 38.39  ? 351 HIS C N   1 
ATOM   6591 C CA  . HIS C 1 277 ? 127.838 135.170 134.394 1.00 35.77  ? 351 HIS C CA  1 
ATOM   6592 C C   . HIS C 1 277 ? 127.492 133.994 135.297 1.00 36.63  ? 351 HIS C C   1 
ATOM   6593 O O   . HIS C 1 277 ? 127.789 134.008 136.495 1.00 41.39  ? 351 HIS C O   1 
ATOM   6594 C CB  . HIS C 1 277 ? 128.442 136.312 135.212 1.00 41.61  ? 351 HIS C CB  1 
ATOM   6595 C CG  . HIS C 1 277 ? 129.905 136.148 135.480 1.00 48.63  ? 351 HIS C CG  1 
ATOM   6596 N ND1 . HIS C 1 277 ? 130.838 136.044 134.470 1.00 43.84  ? 351 HIS C ND1 1 
ATOM   6597 C CD2 . HIS C 1 277 ? 130.596 136.061 136.641 1.00 45.78  ? 351 HIS C CD2 1 
ATOM   6598 C CE1 . HIS C 1 277 ? 132.041 135.904 134.998 1.00 42.64  ? 351 HIS C CE1 1 
ATOM   6599 N NE2 . HIS C 1 277 ? 131.922 135.911 136.314 1.00 45.25  ? 351 HIS C NE2 1 
ATOM   6600 N N   . SER C 1 278 ? 126.864 132.972 134.720 1.00 37.99  ? 352 SER C N   1 
ATOM   6601 C CA  . SER C 1 278 ? 126.493 131.769 135.450 1.00 31.48  ? 352 SER C CA  1 
ATOM   6602 C C   . SER C 1 278 ? 126.337 130.644 134.443 1.00 36.86  ? 352 SER C C   1 
ATOM   6603 O O   . SER C 1 278 ? 125.623 130.799 133.448 1.00 43.27  ? 352 SER C O   1 
ATOM   6604 C CB  . SER C 1 278 ? 125.194 131.971 136.237 1.00 30.61  ? 352 SER C CB  1 
ATOM   6605 O OG  . SER C 1 278 ? 124.816 130.784 136.912 1.00 40.01  ? 352 SER C OG  1 
ATOM   6606 N N   . LEU C 1 279 ? 127.005 129.521 134.697 1.00 28.79  ? 353 LEU C N   1 
ATOM   6607 C CA  . LEU C 1 279 ? 126.954 128.406 133.764 1.00 34.85  ? 353 LEU C CA  1 
ATOM   6608 C C   . LEU C 1 279 ? 125.614 127.681 133.784 1.00 37.35  ? 353 LEU C C   1 
ATOM   6609 O O   . LEU C 1 279 ? 125.297 126.973 132.824 1.00 39.47  ? 353 LEU C O   1 
ATOM   6610 C CB  . LEU C 1 279 ? 128.078 127.414 134.071 1.00 37.23  ? 353 LEU C CB  1 
ATOM   6611 C CG  . LEU C 1 279 ? 129.437 127.989 134.481 1.00 35.32  ? 353 LEU C CG  1 
ATOM   6612 C CD1 . LEU C 1 279 ? 130.385 126.875 134.896 1.00 39.21  ? 353 LEU C CD1 1 
ATOM   6613 C CD2 . LEU C 1 279 ? 130.045 128.820 133.366 1.00 32.55  ? 353 LEU C CD2 1 
ATOM   6614 N N   . SER C 1 280 ? 124.817 127.857 134.838 1.00 41.38  ? 354 SER C N   1 
ATOM   6615 C CA  . SER C 1 280 ? 123.609 127.066 135.038 1.00 38.10  ? 354 SER C CA  1 
ATOM   6616 C C   . SER C 1 280 ? 122.348 127.694 134.463 1.00 41.57  ? 354 SER C C   1 
ATOM   6617 O O   . SER C 1 280 ? 121.314 127.019 134.415 1.00 47.95  ? 354 SER C O   1 
ATOM   6618 C CB  . SER C 1 280 ? 123.380 126.820 136.533 1.00 42.87  ? 354 SER C CB  1 
ATOM   6619 O OG  . SER C 1 280 ? 124.403 126.021 137.096 1.00 49.19  ? 354 SER C OG  1 
ATOM   6620 N N   . PHE C 1 281 ? 122.389 128.951 134.022 1.00 36.76  ? 355 PHE C N   1 
ATOM   6621 C CA  . PHE C 1 281 ? 121.153 129.673 133.725 1.00 35.25  ? 355 PHE C CA  1 
ATOM   6622 C C   . PHE C 1 281 ? 120.700 129.293 132.316 1.00 34.01  ? 355 PHE C C   1 
ATOM   6623 O O   . PHE C 1 281 ? 120.886 130.023 131.339 1.00 38.35  ? 355 PHE C O   1 
ATOM   6624 C CB  . PHE C 1 281 ? 121.347 131.175 133.883 1.00 32.20  ? 355 PHE C CB  1 
ATOM   6625 C CG  . PHE C 1 281 ? 120.099 131.976 133.646 1.00 39.65  ? 355 PHE C CG  1 
ATOM   6626 C CD1 . PHE C 1 281 ? 119.102 132.019 134.602 1.00 42.76  ? 355 PHE C CD1 1 
ATOM   6627 C CD2 . PHE C 1 281 ? 119.918 132.688 132.481 1.00 42.07  ? 355 PHE C CD2 1 
ATOM   6628 C CE1 . PHE C 1 281 ? 117.954 132.757 134.400 1.00 39.40  ? 355 PHE C CE1 1 
ATOM   6629 C CE2 . PHE C 1 281 ? 118.765 133.424 132.273 1.00 40.54  ? 355 PHE C CE2 1 
ATOM   6630 C CZ  . PHE C 1 281 ? 117.785 133.456 133.231 1.00 36.44  ? 355 PHE C CZ  1 
ATOM   6631 N N   . ARG C 1 282 ? 120.108 128.107 132.220 1.00 34.34  ? 356 ARG C N   1 
ATOM   6632 C CA  . ARG C 1 282 ? 119.540 127.646 130.964 1.00 21.90  ? 356 ARG C CA  1 
ATOM   6633 C C   . ARG C 1 282 ? 118.294 128.462 130.623 1.00 34.74  ? 356 ARG C C   1 
ATOM   6634 O O   . ARG C 1 282 ? 117.532 128.835 131.521 1.00 44.79  ? 356 ARG C O   1 
ATOM   6635 C CB  . ARG C 1 282 ? 119.187 126.161 131.061 1.00 26.56  ? 356 ARG C CB  1 
ATOM   6636 C CG  . ARG C 1 282 ? 118.972 125.459 129.732 1.00 36.77  ? 356 ARG C CG  1 
ATOM   6637 C CD  . ARG C 1 282 ? 120.276 125.273 128.978 1.00 39.10  ? 356 ARG C CD  1 
ATOM   6638 N NE  . ARG C 1 282 ? 121.199 124.385 129.675 1.00 36.82  ? 356 ARG C NE  1 
ATOM   6639 C CZ  . ARG C 1 282 ? 121.234 123.069 129.519 1.00 32.06  ? 356 ARG C CZ  1 
ATOM   6640 N NH1 . ARG C 1 282 ? 120.384 122.446 128.719 1.00 34.37  ? 356 ARG C NH1 1 
ATOM   6641 N NH2 . ARG C 1 282 ? 122.143 122.361 130.181 1.00 36.67  ? 356 ARG C NH2 1 
ATOM   6642 N N   . PRO C 1 283 ? 118.066 128.767 129.344 1.00 31.04  ? 357 PRO C N   1 
ATOM   6643 C CA  . PRO C 1 283 ? 116.824 129.452 128.966 1.00 27.67  ? 357 PRO C CA  1 
ATOM   6644 C C   . PRO C 1 283 ? 115.603 128.618 129.322 1.00 28.03  ? 357 PRO C C   1 
ATOM   6645 O O   . PRO C 1 283 ? 115.622 127.387 129.259 1.00 27.12  ? 357 PRO C O   1 
ATOM   6646 C CB  . PRO C 1 283 ? 116.958 129.631 127.448 1.00 30.52  ? 357 PRO C CB  1 
ATOM   6647 C CG  . PRO C 1 283 ? 118.086 128.743 127.030 1.00 28.82  ? 357 PRO C CG  1 
ATOM   6648 C CD  . PRO C 1 283 ? 118.988 128.623 128.208 1.00 32.16  ? 357 PRO C CD  1 
ATOM   6649 N N   . ILE C 1 284 ? 114.528 129.308 129.701 1.00 29.31  ? 358 ILE C N   1 
ATOM   6650 C CA  . ILE C 1 284 ? 113.330 128.653 130.205 1.00 24.94  ? 358 ILE C CA  1 
ATOM   6651 C C   . ILE C 1 284 ? 112.129 129.054 129.357 1.00 29.84  ? 358 ILE C C   1 
ATOM   6652 O O   . ILE C 1 284 ? 112.128 130.075 128.663 1.00 37.99  ? 358 ILE C O   1 
ATOM   6653 C CB  . ILE C 1 284 ? 113.071 128.972 131.692 1.00 22.28  ? 358 ILE C CB  1 
ATOM   6654 C CG1 . ILE C 1 284 ? 112.707 130.445 131.868 1.00 27.01  ? 358 ILE C CG1 1 
ATOM   6655 C CG2 . ILE C 1 284 ? 114.287 128.621 132.533 1.00 28.81  ? 358 ILE C CG2 1 
ATOM   6656 C CD1 . ILE C 1 284 ? 112.617 130.885 133.311 1.00 33.16  ? 358 ILE C CD1 1 
ATOM   6657 N N   . VAL C 1 285 ? 111.095 128.218 129.423 1.00 29.70  ? 359 VAL C N   1 
ATOM   6658 C CA  . VAL C 1 285 ? 109.845 128.420 128.701 1.00 22.77  ? 359 VAL C CA  1 
ATOM   6659 C C   . VAL C 1 285 ? 108.703 128.338 129.706 1.00 27.16  ? 359 VAL C C   1 
ATOM   6660 O O   . VAL C 1 285 ? 108.627 127.384 130.487 1.00 37.67  ? 359 VAL C O   1 
ATOM   6661 C CB  . VAL C 1 285 ? 109.664 127.380 127.579 1.00 20.94  ? 359 VAL C CB  1 
ATOM   6662 C CG1 . VAL C 1 285 ? 108.315 127.543 126.917 1.00 28.38  ? 359 VAL C CG1 1 
ATOM   6663 C CG2 . VAL C 1 285 ? 110.779 127.505 126.554 1.00 29.50  ? 359 VAL C CG2 1 
ATOM   6664 N N   . VAL C 1 286 ? 107.821 129.327 129.680 1.00 24.56  ? 360 VAL C N   1 
ATOM   6665 C CA  . VAL C 1 286 ? 106.773 129.478 130.687 1.00 20.18  ? 360 VAL C CA  1 
ATOM   6666 C C   . VAL C 1 286 ? 105.435 129.541 129.964 1.00 24.79  ? 360 VAL C C   1 
ATOM   6667 O O   . VAL C 1 286 ? 105.373 129.854 128.762 1.00 33.76  ? 360 VAL C O   1 
ATOM   6668 C CB  . VAL C 1 286 ? 107.003 130.727 131.570 1.00 17.10  ? 360 VAL C CB  1 
ATOM   6669 C CG1 . VAL C 1 286 ? 108.303 130.598 132.343 1.00 25.98  ? 360 VAL C CG1 1 
ATOM   6670 C CG2 . VAL C 1 286 ? 107.008 131.984 130.719 1.00 28.07  ? 360 VAL C CG2 1 
ATOM   6671 N N   . PRO C 1 287 ? 104.339 129.229 130.659 1.00 25.38  ? 361 PRO C N   1 
ATOM   6672 C CA  . PRO C 1 287 ? 103.018 129.302 130.024 1.00 23.93  ? 361 PRO C CA  1 
ATOM   6673 C C   . PRO C 1 287 ? 102.675 130.715 129.579 1.00 24.56  ? 361 PRO C C   1 
ATOM   6674 O O   . PRO C 1 287 ? 103.140 131.704 130.148 1.00 34.61  ? 361 PRO C O   1 
ATOM   6675 C CB  . PRO C 1 287 ? 102.068 128.818 131.124 1.00 23.19  ? 361 PRO C CB  1 
ATOM   6676 C CG  . PRO C 1 287 ? 102.914 127.974 132.003 1.00 17.04  ? 361 PRO C CG  1 
ATOM   6677 C CD  . PRO C 1 287 ? 104.271 128.606 131.992 1.00 26.02  ? 361 PRO C CD  1 
ATOM   6678 N N   . ALA C 1 288 ? 101.851 130.799 128.532 1.00 24.27  ? 362 ALA C N   1 
ATOM   6679 C CA  . ALA C 1 288 ? 101.477 132.091 127.971 1.00 24.74  ? 362 ALA C CA  1 
ATOM   6680 C C   . ALA C 1 288 ? 100.573 132.896 128.895 1.00 25.29  ? 362 ALA C C   1 
ATOM   6681 O O   . ALA C 1 288 ? 100.472 134.116 128.730 1.00 33.61  ? 362 ALA C O   1 
ATOM   6682 C CB  . ALA C 1 288 ? 100.790 131.896 126.619 1.00 25.77  ? 362 ALA C CB  1 
ATOM   6683 N N   . GLY C 1 289 ? 99.919  132.253 129.857 1.00 28.23  ? 363 GLY C N   1 
ATOM   6684 C CA  . GLY C 1 289 ? 98.992  132.944 130.726 1.00 23.11  ? 363 GLY C CA  1 
ATOM   6685 C C   . GLY C 1 289 ? 99.588  133.622 131.937 1.00 26.74  ? 363 GLY C C   1 
ATOM   6686 O O   . GLY C 1 289 ? 98.843  134.197 132.735 1.00 35.10  ? 363 GLY C O   1 
ATOM   6687 N N   . VAL C 1 290 ? 100.908 133.576 132.107 1.00 28.97  ? 364 VAL C N   1 
ATOM   6688 C CA  . VAL C 1 290 ? 101.549 134.156 133.282 1.00 27.12  ? 364 VAL C CA  1 
ATOM   6689 C C   . VAL C 1 290 ? 101.844 135.630 133.038 1.00 21.21  ? 364 VAL C C   1 
ATOM   6690 O O   . VAL C 1 290 ? 101.801 136.105 131.898 1.00 31.42  ? 364 VAL C O   1 
ATOM   6691 C CB  . VAL C 1 290 ? 102.838 133.399 133.652 1.00 25.21  ? 364 VAL C CB  1 
ATOM   6692 C CG1 . VAL C 1 290 ? 102.536 131.932 133.921 1.00 31.82  ? 364 VAL C CG1 1 
ATOM   6693 C CG2 . VAL C 1 290 ? 103.882 133.558 132.563 1.00 22.56  ? 364 VAL C CG2 1 
ATOM   6694 N N   . GLU C 1 291 ? 102.142 136.359 134.110 1.00 27.45  ? 365 GLU C N   1 
ATOM   6695 C CA  . GLU C 1 291 ? 102.525 137.761 134.043 1.00 26.80  ? 365 GLU C CA  1 
ATOM   6696 C C   . GLU C 1 291 ? 103.951 137.911 134.552 1.00 28.13  ? 365 GLU C C   1 
ATOM   6697 O O   . GLU C 1 291 ? 104.274 137.443 135.648 1.00 34.36  ? 365 GLU C O   1 
ATOM   6698 C CB  . GLU C 1 291 ? 101.574 138.635 134.866 1.00 26.67  ? 365 GLU C CB  1 
ATOM   6699 C CG  . GLU C 1 291 ? 101.932 140.112 134.865 1.00 32.26  ? 365 GLU C CG  1 
ATOM   6700 C CD  . GLU C 1 291 ? 100.710 141.008 134.862 1.00 36.95  ? 365 GLU C CD  1 
ATOM   6701 O OE1 . GLU C 1 291 ? 99.581  140.475 134.862 1.00 40.50  ? 365 GLU C OE1 1 
ATOM   6702 O OE2 . GLU C 1 291 ? 100.878 142.246 134.860 1.00 32.30  ? 365 GLU C OE2 1 
ATOM   6703 N N   . LEU C 1 292 ? 104.797 138.559 133.758 1.00 20.45  ? 366 LEU C N   1 
ATOM   6704 C CA  . LEU C 1 292 ? 106.188 138.799 134.113 1.00 14.41  ? 366 LEU C CA  1 
ATOM   6705 C C   . LEU C 1 292 ? 106.361 140.250 134.537 1.00 21.75  ? 366 LEU C C   1 
ATOM   6706 O O   . LEU C 1 292 ? 105.718 141.146 133.984 1.00 33.31  ? 366 LEU C O   1 
ATOM   6707 C CB  . LEU C 1 292 ? 107.125 138.484 132.944 1.00 23.77  ? 366 LEU C CB  1 
ATOM   6708 C CG  . LEU C 1 292 ? 107.488 137.023 132.672 1.00 14.04  ? 366 LEU C CG  1 
ATOM   6709 C CD1 . LEU C 1 292 ? 106.313 136.255 132.096 1.00 25.93  ? 366 LEU C CD1 1 
ATOM   6710 C CD2 . LEU C 1 292 ? 108.679 136.951 131.737 1.00 25.03  ? 366 LEU C CD2 1 
ATOM   6711 N N   . LYS C 1 293 ? 107.234 140.477 135.514 1.00 24.11  ? 367 LYS C N   1 
ATOM   6712 C CA  . LYS C 1 293 ? 107.468 141.818 136.046 1.00 22.22  ? 367 LYS C CA  1 
ATOM   6713 C C   . LYS C 1 293 ? 108.965 141.994 136.261 1.00 26.24  ? 367 LYS C C   1 
ATOM   6714 O O   . LYS C 1 293 ? 109.526 141.443 137.209 1.00 37.13  ? 367 LYS C O   1 
ATOM   6715 C CB  . LYS C 1 293 ? 106.697 142.032 137.348 1.00 31.82  ? 367 LYS C CB  1 
ATOM   6716 C CG  . LYS C 1 293 ? 106.830 143.420 137.947 1.00 29.20  ? 367 LYS C CG  1 
ATOM   6717 C CD  . LYS C 1 293 ? 105.941 143.562 139.171 1.00 33.33  ? 367 LYS C CD  1 
ATOM   6718 C CE  . LYS C 1 293 ? 106.163 144.887 139.875 1.00 34.32  ? 367 LYS C CE  1 
ATOM   6719 N NZ  . LYS C 1 293 ? 105.734 146.035 139.033 1.00 39.72  ? 367 LYS C NZ  1 
ATOM   6720 N N   . ILE C 1 294 ? 109.607 142.762 135.392 1.00 24.86  ? 368 ILE C N   1 
ATOM   6721 C CA  . ILE C 1 294 ? 111.049 142.969 135.437 1.00 25.18  ? 368 ILE C CA  1 
ATOM   6722 C C   . ILE C 1 294 ? 111.331 144.322 136.074 1.00 29.95  ? 368 ILE C C   1 
ATOM   6723 O O   . ILE C 1 294 ? 110.750 145.342 135.675 1.00 37.95  ? 368 ILE C O   1 
ATOM   6724 C CB  . ILE C 1 294 ? 111.670 142.877 134.034 1.00 26.52  ? 368 ILE C CB  1 
ATOM   6725 C CG1 . ILE C 1 294 ? 111.445 141.483 133.446 1.00 26.62  ? 368 ILE C CG1 1 
ATOM   6726 C CG2 . ILE C 1 294 ? 113.152 143.186 134.090 1.00 29.20  ? 368 ILE C CG2 1 
ATOM   6727 C CD1 . ILE C 1 294 ? 111.834 141.364 131.991 1.00 29.50  ? 368 ILE C CD1 1 
ATOM   6728 N N   . MET C 1 295 ? 112.207 144.326 137.082 1.00 35.00  ? 369 MET C N   1 
ATOM   6729 C CA  . MET C 1 295 ? 112.614 145.549 137.763 1.00 28.93  ? 369 MET C CA  1 
ATOM   6730 C C   . MET C 1 295 ? 114.117 145.506 138.005 1.00 35.99  ? 369 MET C C   1 
ATOM   6731 O O   . MET C 1 295 ? 114.784 144.504 137.735 1.00 44.59  ? 369 MET C O   1 
ATOM   6732 C CB  . MET C 1 295 ? 111.872 145.740 139.093 1.00 28.93  ? 369 MET C CB  1 
ATOM   6733 C CG  . MET C 1 295 ? 110.423 145.292 139.105 1.00 37.47  ? 369 MET C CG  1 
ATOM   6734 S SD  . MET C 1 295 ? 109.727 145.322 140.767 1.00 49.09  ? 369 MET C SD  1 
ATOM   6735 C CE  . MET C 1 295 ? 109.763 147.077 141.115 1.00 39.75  ? 369 MET C CE  1 
ATOM   6736 N N   . LEU C 1 296 ? 114.652 146.609 138.521 1.00 35.32  ? 370 LEU C N   1 
ATOM   6737 C CA  . LEU C 1 296 ? 116.028 146.652 138.992 1.00 33.91  ? 370 LEU C CA  1 
ATOM   6738 C C   . LEU C 1 296 ? 116.083 146.255 140.460 1.00 44.47  ? 370 LEU C C   1 
ATOM   6739 O O   . LEU C 1 296 ? 115.254 146.689 141.265 1.00 51.45  ? 370 LEU C O   1 
ATOM   6740 C CB  . LEU C 1 296 ? 116.633 148.045 138.811 1.00 34.62  ? 370 LEU C CB  1 
ATOM   6741 C CG  . LEU C 1 296 ? 116.942 148.527 137.394 1.00 36.64  ? 370 LEU C CG  1 
ATOM   6742 C CD1 . LEU C 1 296 ? 117.389 149.973 137.418 1.00 40.55  ? 370 LEU C CD1 1 
ATOM   6743 C CD2 . LEU C 1 296 ? 118.017 147.664 136.773 1.00 40.75  ? 370 LEU C CD2 1 
ATOM   6744 N N   . SER C 1 297 ? 117.062 145.423 140.802 1.00 38.49  ? 371 SER C N   1 
ATOM   6745 C CA  . SER C 1 297 ? 117.238 145.022 142.186 1.00 37.96  ? 371 SER C CA  1 
ATOM   6746 C C   . SER C 1 297 ? 117.671 146.222 143.029 1.00 39.43  ? 371 SER C C   1 
ATOM   6747 O O   . SER C 1 297 ? 118.320 147.141 142.524 1.00 47.91  ? 371 SER C O   1 
ATOM   6748 C CB  . SER C 1 297 ? 118.270 143.904 142.292 1.00 43.90  ? 371 SER C CB  1 
ATOM   6749 O OG  . SER C 1 297 ? 119.555 144.351 141.903 1.00 45.56  ? 371 SER C OG  1 
ATOM   6750 N N   . PRO C 1 298 ? 117.298 146.251 144.312 1.00 34.37  ? 372 PRO C N   1 
ATOM   6751 C CA  . PRO C 1 298 ? 117.701 147.391 145.155 1.00 43.01  ? 372 PRO C CA  1 
ATOM   6752 C C   . PRO C 1 298 ? 119.206 147.569 145.249 1.00 48.01  ? 372 PRO C C   1 
ATOM   6753 O O   . PRO C 1 298 ? 119.689 148.706 145.305 1.00 49.68  ? 372 PRO C O   1 
ATOM   6754 C CB  . PRO C 1 298 ? 117.076 147.057 146.518 1.00 48.42  ? 372 PRO C CB  1 
ATOM   6755 C CG  . PRO C 1 298 ? 116.817 145.584 146.480 1.00 48.52  ? 372 PRO C CG  1 
ATOM   6756 C CD  . PRO C 1 298 ? 116.497 145.265 145.056 1.00 41.10  ? 372 PRO C CD  1 
ATOM   6757 N N   . GLU C 1 299 ? 119.961 146.476 145.268 1.00 54.82  ? 373 GLU C N   1 
ATOM   6758 C CA  . GLU C 1 299 ? 121.422 146.536 145.311 1.00 55.73  ? 373 GLU C CA  1 
ATOM   6759 C C   . GLU C 1 299 ? 122.008 146.382 143.908 1.00 56.21  ? 373 GLU C C   1 
ATOM   6760 O O   . GLU C 1 299 ? 122.781 145.467 143.623 1.00 60.07  ? 373 GLU C O   1 
ATOM   6761 C CB  . GLU C 1 299 ? 121.978 145.455 146.240 1.00 57.96  ? 373 GLU C CB  1 
ATOM   6762 C CG  . GLU C 1 299 ? 123.490 145.491 146.400 1.00 61.31  ? 373 GLU C CG  1 
ATOM   6763 C CD  . GLU C 1 299 ? 123.998 144.436 147.365 1.00 63.40  ? 373 GLU C CD  1 
ATOM   6764 O OE1 . GLU C 1 299 ? 123.173 143.653 147.879 1.00 62.87  ? 373 GLU C OE1 1 
ATOM   6765 O OE2 . GLU C 1 299 ? 125.222 144.393 147.611 1.00 63.50  ? 373 GLU C OE2 1 
ATOM   6766 N N   . ALA C 1 300 ? 121.627 147.298 143.021 1.00 51.17  ? 374 ALA C N   1 
ATOM   6767 C CA  . ALA C 1 300 ? 122.067 147.265 141.632 1.00 52.17  ? 374 ALA C CA  1 
ATOM   6768 C C   . ALA C 1 300 ? 122.715 148.588 141.263 1.00 53.58  ? 374 ALA C C   1 
ATOM   6769 O O   . ALA C 1 300 ? 122.157 149.656 141.537 1.00 51.07  ? 374 ALA C O   1 
ATOM   6770 C CB  . ALA C 1 300 ? 120.900 146.976 140.682 1.00 52.60  ? 374 ALA C CB  1 
ATOM   6771 N N   . ARG C 1 301 ? 123.888 148.513 140.645 1.00 66.43  ? 375 ARG C N   1 
ATOM   6772 C CA  . ARG C 1 301 ? 124.550 149.683 140.093 1.00 63.44  ? 375 ARG C CA  1 
ATOM   6773 C C   . ARG C 1 301 ? 124.066 149.927 138.670 1.00 66.04  ? 375 ARG C C   1 
ATOM   6774 O O   . ARG C 1 301 ? 123.701 148.992 137.951 1.00 69.00  ? 375 ARG C O   1 
ATOM   6775 C CB  . ARG C 1 301 ? 126.069 149.505 140.106 1.00 64.07  ? 375 ARG C CB  1 
ATOM   6776 C CG  . ARG C 1 301 ? 126.700 149.638 141.482 1.00 65.94  ? 375 ARG C CG  1 
ATOM   6777 C CD  . ARG C 1 301 ? 127.954 148.787 141.598 1.00 67.36  ? 375 ARG C CD  1 
ATOM   6778 N NE  . ARG C 1 301 ? 129.027 149.275 140.740 1.00 70.96  ? 375 ARG C NE  1 
ATOM   6779 C CZ  . ARG C 1 301 ? 130.227 148.718 140.652 1.00 70.01  ? 375 ARG C CZ  1 
ATOM   6780 N NH1 . ARG C 1 301 ? 130.545 147.645 141.358 1.00 67.63  ? 375 ARG C NH1 1 
ATOM   6781 N NH2 . ARG C 1 301 ? 131.131 149.250 139.834 1.00 70.32  ? 375 ARG C NH2 1 
ATOM   6782 N N   . ASN C 1 302 ? 124.049 151.204 138.280 1.00 59.57  ? 376 ASN C N   1 
ATOM   6783 C CA  . ASN C 1 302 ? 123.645 151.640 136.945 1.00 56.05  ? 376 ASN C CA  1 
ATOM   6784 C C   . ASN C 1 302 ? 122.169 151.370 136.673 1.00 54.91  ? 376 ASN C C   1 
ATOM   6785 O O   . ASN C 1 302 ? 121.517 150.612 137.399 1.00 57.85  ? 376 ASN C O   1 
ATOM   6786 C CB  . ASN C 1 302 ? 124.509 150.971 135.870 1.00 56.27  ? 376 ASN C CB  1 
ATOM   6787 C CG  . ASN C 1 302 ? 125.969 151.363 135.967 1.00 62.66  ? 376 ASN C CG  1 
ATOM   6788 O OD1 . ASN C 1 302 ? 126.829 150.530 136.251 1.00 64.78  ? 376 ASN C OD1 1 
ATOM   6789 N ND2 . ASN C 1 302 ? 126.256 152.637 135.729 1.00 61.69  ? 376 ASN C ND2 1 
ATOM   6790 N N   . THR C 1 303 ? 121.633 151.999 135.632 1.00 46.73  ? 377 THR C N   1 
ATOM   6791 C CA  . THR C 1 303 ? 120.254 151.816 135.216 1.00 42.17  ? 377 THR C CA  1 
ATOM   6792 C C   . THR C 1 303 ? 120.194 150.799 134.080 1.00 43.63  ? 377 THR C C   1 
ATOM   6793 O O   . THR C 1 303 ? 121.217 150.349 133.561 1.00 50.19  ? 377 THR C O   1 
ATOM   6794 C CB  . THR C 1 303 ? 119.644 153.153 134.793 1.00 44.63  ? 377 THR C CB  1 
ATOM   6795 O OG1 . THR C 1 303 ? 120.206 153.558 133.539 1.00 46.96  ? 377 THR C OG1 1 
ATOM   6796 C CG2 . THR C 1 303 ? 119.932 154.220 135.837 1.00 46.36  ? 377 THR C CG2 1 
ATOM   6797 N N   . ALA C 1 304 ? 118.978 150.427 133.686 1.00 43.85  ? 378 ALA C N   1 
ATOM   6798 C CA  . ALA C 1 304 ? 118.805 149.451 132.621 1.00 39.05  ? 378 ALA C CA  1 
ATOM   6799 C C   . ALA C 1 304 ? 118.138 150.106 131.420 1.00 45.11  ? 378 ALA C C   1 
ATOM   6800 O O   . ALA C 1 304 ? 117.568 151.195 131.521 1.00 50.36  ? 378 ALA C O   1 
ATOM   6801 C CB  . ALA C 1 304 ? 117.984 148.244 133.092 1.00 44.21  ? 378 ALA C CB  1 
ATOM   6802 N N   . TRP C 1 305 ? 118.210 149.434 130.272 1.00 43.12  ? 379 TRP C N   1 
ATOM   6803 C CA  . TRP C 1 305 ? 117.643 149.954 129.036 1.00 42.88  ? 379 TRP C CA  1 
ATOM   6804 C C   . TRP C 1 305 ? 116.719 148.911 128.427 1.00 40.41  ? 379 TRP C C   1 
ATOM   6805 O O   . TRP C 1 305 ? 117.095 147.744 128.296 1.00 48.00  ? 379 TRP C O   1 
ATOM   6806 C CB  . TRP C 1 305 ? 118.744 150.336 128.045 1.00 42.65  ? 379 TRP C CB  1 
ATOM   6807 C CG  . TRP C 1 305 ? 119.514 151.547 128.460 1.00 40.77  ? 379 TRP C CG  1 
ATOM   6808 C CD1 . TRP C 1 305 ? 120.620 151.581 129.256 1.00 45.59  ? 379 TRP C CD1 1 
ATOM   6809 C CD2 . TRP C 1 305 ? 119.232 152.905 128.107 1.00 44.84  ? 379 TRP C CD2 1 
ATOM   6810 N NE1 . TRP C 1 305 ? 121.047 152.876 129.418 1.00 49.01  ? 379 TRP C NE1 1 
ATOM   6811 C CE2 . TRP C 1 305 ? 120.212 153.708 128.722 1.00 44.35  ? 379 TRP C CE2 1 
ATOM   6812 C CE3 . TRP C 1 305 ? 118.248 153.520 127.328 1.00 46.61  ? 379 TRP C CE3 1 
ATOM   6813 C CZ2 . TRP C 1 305 ? 120.235 155.093 128.584 1.00 43.46  ? 379 TRP C CZ2 1 
ATOM   6814 C CZ3 . TRP C 1 305 ? 118.273 154.895 127.192 1.00 44.38  ? 379 TRP C CZ3 1 
ATOM   6815 C CH2 . TRP C 1 305 ? 119.259 155.666 127.816 1.00 43.44  ? 379 TRP C CH2 1 
ATOM   6816 N N   . VAL C 1 306 ? 115.518 149.340 128.050 1.00 32.30  ? 380 VAL C N   1 
ATOM   6817 C CA  . VAL C 1 306 ? 114.496 148.466 127.487 1.00 26.56  ? 380 VAL C CA  1 
ATOM   6818 C C   . VAL C 1 306 ? 114.275 148.848 126.029 1.00 35.77  ? 380 VAL C C   1 
ATOM   6819 O O   . VAL C 1 306 ? 114.173 150.036 125.694 1.00 48.10  ? 380 VAL C O   1 
ATOM   6820 C CB  . VAL C 1 306 ? 113.188 148.534 128.297 1.00 32.43  ? 380 VAL C CB  1 
ATOM   6821 C CG1 . VAL C 1 306 ? 112.615 149.944 128.304 1.00 39.92  ? 380 VAL C CG1 1 
ATOM   6822 C CG2 . VAL C 1 306 ? 112.174 147.554 127.743 1.00 30.47  ? 380 VAL C CG2 1 
ATOM   6823 N N   . SER C 1 307 ? 114.236 147.839 125.162 1.00 34.54  ? 381 SER C N   1 
ATOM   6824 C CA  . SER C 1 307 ? 114.008 148.013 123.736 1.00 35.20  ? 381 SER C CA  1 
ATOM   6825 C C   . SER C 1 307 ? 112.920 147.052 123.285 1.00 36.19  ? 381 SER C C   1 
ATOM   6826 O O   . SER C 1 307 ? 112.879 145.895 123.718 1.00 35.66  ? 381 SER C O   1 
ATOM   6827 C CB  . SER C 1 307 ? 115.290 147.773 122.931 1.00 38.09  ? 381 SER C CB  1 
ATOM   6828 O OG  . SER C 1 307 ? 115.496 146.391 122.702 1.00 43.19  ? 381 SER C OG  1 
ATOM   6829 N N   . PHE C 1 308 ? 112.040 147.539 122.414 1.00 39.76  ? 382 PHE C N   1 
ATOM   6830 C CA  . PHE C 1 308 ? 110.881 146.789 121.944 1.00 29.37  ? 382 PHE C CA  1 
ATOM   6831 C C   . PHE C 1 308 ? 111.058 146.494 120.460 1.00 36.18  ? 382 PHE C C   1 
ATOM   6832 O O   . PHE C 1 308 ? 110.919 147.392 119.624 1.00 47.93  ? 382 PHE C O   1 
ATOM   6833 C CB  . PHE C 1 308 ? 109.594 147.570 122.199 1.00 35.36  ? 382 PHE C CB  1 
ATOM   6834 C CG  . PHE C 1 308 ? 109.452 148.061 123.611 1.00 32.96  ? 382 PHE C CG  1 
ATOM   6835 C CD1 . PHE C 1 308 ? 108.850 147.271 124.574 1.00 35.87  ? 382 PHE C CD1 1 
ATOM   6836 C CD2 . PHE C 1 308 ? 109.911 149.315 123.974 1.00 34.10  ? 382 PHE C CD2 1 
ATOM   6837 C CE1 . PHE C 1 308 ? 108.715 147.718 125.872 1.00 37.73  ? 382 PHE C CE1 1 
ATOM   6838 C CE2 . PHE C 1 308 ? 109.778 149.767 125.271 1.00 36.30  ? 382 PHE C CE2 1 
ATOM   6839 C CZ  . PHE C 1 308 ? 109.179 148.968 126.220 1.00 37.63  ? 382 PHE C CZ  1 
ATOM   6840 N N   . ASP C 1 309 ? 111.358 145.234 120.139 1.00 38.88  ? 383 ASP C N   1 
ATOM   6841 C CA  . ASP C 1 309 ? 111.542 144.786 118.757 1.00 36.34  ? 383 ASP C CA  1 
ATOM   6842 C C   . ASP C 1 309 ? 112.651 145.565 118.054 1.00 37.77  ? 383 ASP C C   1 
ATOM   6843 O O   . ASP C 1 309 ? 112.545 145.899 116.872 1.00 42.59  ? 383 ASP C O   1 
ATOM   6844 C CB  . ASP C 1 309 ? 110.235 144.880 117.966 1.00 39.15  ? 383 ASP C CB  1 
ATOM   6845 C CG  . ASP C 1 309 ? 109.346 143.670 118.161 1.00 46.60  ? 383 ASP C CG  1 
ATOM   6846 O OD1 . ASP C 1 309 ? 109.883 142.553 118.298 1.00 50.65  ? 383 ASP C OD1 1 
ATOM   6847 O OD2 . ASP C 1 309 ? 108.109 143.837 118.171 1.00 47.67  ? 383 ASP C OD2 1 
ATOM   6848 N N   . GLY C 1 310 ? 113.729 145.851 118.781 1.00 41.70  ? 384 GLY C N   1 
ATOM   6849 C CA  . GLY C 1 310 ? 114.840 146.591 118.213 1.00 42.30  ? 384 GLY C CA  1 
ATOM   6850 C C   . GLY C 1 310 ? 114.460 147.996 117.794 1.00 44.43  ? 384 GLY C C   1 
ATOM   6851 O O   . GLY C 1 310 ? 114.790 148.435 116.688 1.00 52.84  ? 384 GLY C O   1 
ATOM   6852 N N   . ARG C 1 311 ? 113.768 148.709 118.673 1.00 45.00  ? 385 ARG C N   1 
ATOM   6853 C CA  . ARG C 1 311 ? 113.216 150.022 118.360 1.00 43.69  ? 385 ARG C CA  1 
ATOM   6854 C C   . ARG C 1 311 ? 113.443 150.917 119.573 1.00 51.44  ? 385 ARG C C   1 
ATOM   6855 O O   . ARG C 1 311 ? 114.298 150.631 120.418 1.00 58.85  ? 385 ARG C O   1 
ATOM   6856 C CB  . ARG C 1 311 ? 111.742 149.907 117.945 1.00 47.96  ? 385 ARG C CB  1 
ATOM   6857 C CG  . ARG C 1 311 ? 111.559 149.517 116.488 1.00 50.51  ? 385 ARG C CG  1 
ATOM   6858 C CD  . ARG C 1 311 ? 110.287 148.715 116.272 1.00 51.50  ? 385 ARG C CD  1 
ATOM   6859 N NE  . ARG C 1 311 ? 109.912 148.668 114.863 1.00 53.79  ? 385 ARG C NE  1 
ATOM   6860 C CZ  . ARG C 1 311 ? 110.466 147.863 113.967 1.00 55.89  ? 385 ARG C CZ  1 
ATOM   6861 N NH1 . ARG C 1 311 ? 111.424 147.013 114.300 1.00 53.25  ? 385 ARG C NH1 1 
ATOM   6862 N NH2 . ARG C 1 311 ? 110.051 147.913 112.705 1.00 55.07  ? 385 ARG C NH2 1 
ATOM   6863 N N   . LYS C 1 312 ? 112.691 152.018 119.640 1.00 57.31  ? 386 LYS C N   1 
ATOM   6864 C CA  . LYS C 1 312 ? 112.893 153.102 120.599 1.00 61.10  ? 386 LYS C CA  1 
ATOM   6865 C C   . LYS C 1 312 ? 113.285 152.587 121.976 1.00 59.61  ? 386 LYS C C   1 
ATOM   6866 O O   . LYS C 1 312 ? 112.564 151.793 122.588 1.00 58.29  ? 386 LYS C O   1 
ATOM   6867 C CB  . LYS C 1 312 ? 111.613 153.936 120.702 1.00 59.20  ? 386 LYS C CB  1 
ATOM   6868 C CG  . LYS C 1 312 ? 111.218 154.640 119.416 1.00 60.38  ? 386 LYS C CG  1 
ATOM   6869 C CD  . LYS C 1 312 ? 109.981 155.500 119.619 1.00 59.58  ? 386 LYS C CD  1 
ATOM   6870 C CE  . LYS C 1 312 ? 108.741 154.643 119.820 1.00 60.44  ? 386 LYS C CE  1 
ATOM   6871 N NZ  . LYS C 1 312 ? 108.396 153.870 118.595 1.00 60.69  ? 386 LYS C NZ  1 
ATOM   6872 N N   . ARG C 1 313 ? 114.436 153.046 122.458 1.00 50.64  ? 387 ARG C N   1 
ATOM   6873 C CA  . ARG C 1 313 ? 115.033 152.560 123.692 1.00 47.88  ? 387 ARG C CA  1 
ATOM   6874 C C   . ARG C 1 313 ? 114.694 153.507 124.833 1.00 48.87  ? 387 ARG C C   1 
ATOM   6875 O O   . ARG C 1 313 ? 114.861 154.724 124.707 1.00 56.17  ? 387 ARG C O   1 
ATOM   6876 C CB  . ARG C 1 313 ? 116.549 152.436 123.542 1.00 47.31  ? 387 ARG C CB  1 
ATOM   6877 C CG  . ARG C 1 313 ? 116.990 151.376 122.550 1.00 47.61  ? 387 ARG C CG  1 
ATOM   6878 C CD  . ARG C 1 313 ? 118.503 151.351 122.400 1.00 52.24  ? 387 ARG C CD  1 
ATOM   6879 N NE  . ARG C 1 313 ? 119.181 150.957 123.628 1.00 48.47  ? 387 ARG C NE  1 
ATOM   6880 C CZ  . ARG C 1 313 ? 119.445 149.703 123.968 1.00 54.46  ? 387 ARG C CZ  1 
ATOM   6881 N NH1 . ARG C 1 313 ? 119.092 148.689 123.195 1.00 53.99  ? 387 ARG C NH1 1 
ATOM   6882 N NH2 . ARG C 1 313 ? 120.081 149.460 125.110 1.00 57.53  ? 387 ARG C NH2 1 
ATOM   6883 N N   . GLN C 1 314 ? 114.220 152.947 125.941 1.00 39.11  ? 388 GLN C N   1 
ATOM   6884 C CA  . GLN C 1 314 ? 113.920 153.719 127.134 1.00 41.23  ? 388 GLN C CA  1 
ATOM   6885 C C   . GLN C 1 314 ? 114.851 153.294 128.260 1.00 49.42  ? 388 GLN C C   1 
ATOM   6886 O O   . GLN C 1 314 ? 115.423 152.203 128.242 1.00 51.42  ? 388 GLN C O   1 
ATOM   6887 C CB  . GLN C 1 314 ? 112.457 153.546 127.563 1.00 43.46  ? 388 GLN C CB  1 
ATOM   6888 C CG  . GLN C 1 314 ? 111.458 153.681 126.429 1.00 45.94  ? 388 GLN C CG  1 
ATOM   6889 C CD  . GLN C 1 314 ? 110.024 153.673 126.914 1.00 52.67  ? 388 GLN C CD  1 
ATOM   6890 O OE1 . GLN C 1 314 ? 109.086 153.671 126.116 1.00 52.90  ? 388 GLN C OE1 1 
ATOM   6891 N NE2 . GLN C 1 314 ? 109.844 153.668 128.229 1.00 52.58  ? 388 GLN C NE2 1 
ATOM   6892 N N   . GLU C 1 315 ? 115.007 154.175 129.242 1.00 49.28  ? 389 GLU C N   1 
ATOM   6893 C CA  . GLU C 1 315 ? 115.851 153.917 130.400 1.00 41.55  ? 389 GLU C CA  1 
ATOM   6894 C C   . GLU C 1 315 ? 114.974 153.713 131.625 1.00 44.80  ? 389 GLU C C   1 
ATOM   6895 O O   . GLU C 1 315 ? 114.081 154.523 131.895 1.00 49.95  ? 389 GLU C O   1 
ATOM   6896 C CB  . GLU C 1 315 ? 116.830 155.068 130.634 1.00 47.27  ? 389 GLU C CB  1 
ATOM   6897 C CG  . GLU C 1 315 ? 117.856 154.791 131.717 1.00 50.15  ? 389 GLU C CG  1 
ATOM   6898 C CD  . GLU C 1 315 ? 118.645 156.025 132.103 1.00 49.72  ? 389 GLU C CD  1 
ATOM   6899 O OE1 . GLU C 1 315 ? 118.229 157.140 131.727 1.00 50.19  ? 389 GLU C OE1 1 
ATOM   6900 O OE2 . GLU C 1 315 ? 119.682 155.879 132.783 1.00 52.11  ? 389 GLU C OE2 1 
ATOM   6901 N N   . ILE C 1 316 ? 115.227 152.634 132.360 1.00 46.43  ? 390 ILE C N   1 
ATOM   6902 C CA  . ILE C 1 316 ? 114.493 152.322 133.578 1.00 47.71  ? 390 ILE C CA  1 
ATOM   6903 C C   . ILE C 1 316 ? 115.449 152.408 134.761 1.00 47.30  ? 390 ILE C C   1 
ATOM   6904 O O   . ILE C 1 316 ? 116.569 151.876 134.713 1.00 50.93  ? 390 ILE C O   1 
ATOM   6905 C CB  . ILE C 1 316 ? 113.804 150.945 133.506 1.00 42.03  ? 390 ILE C CB  1 
ATOM   6906 C CG1 . ILE C 1 316 ? 114.819 149.816 133.351 1.00 43.62  ? 390 ILE C CG1 1 
ATOM   6907 C CG2 . ILE C 1 316 ? 112.799 150.913 132.365 1.00 44.30  ? 390 ILE C CG2 1 
ATOM   6908 C CD1 . ILE C 1 316 ? 114.223 148.449 133.560 1.00 47.43  ? 390 ILE C CD1 1 
ATOM   6909 N N   . ARG C 1 317 ? 115.011 153.115 135.800 1.00 51.16  ? 391 ARG C N   1 
ATOM   6910 C CA  . ARG C 1 317 ? 115.720 153.308 137.051 1.00 48.48  ? 391 ARG C CA  1 
ATOM   6911 C C   . ARG C 1 317 ? 115.125 152.395 138.122 1.00 51.56  ? 391 ARG C C   1 
ATOM   6912 O O   . ARG C 1 317 ? 114.316 151.507 137.835 1.00 59.50  ? 391 ARG C O   1 
ATOM   6913 C CB  . ARG C 1 317 ? 115.670 154.782 137.463 1.00 52.05  ? 391 ARG C CB  1 
ATOM   6914 C CG  . ARG C 1 317 ? 116.625 155.688 136.698 1.00 54.02  ? 391 ARG C CG  1 
ATOM   6915 C CD  . ARG C 1 317 ? 116.052 156.118 135.357 1.00 52.10  ? 391 ARG C CD  1 
ATOM   6916 N NE  . ARG C 1 317 ? 114.780 156.815 135.502 1.00 54.83  ? 391 ARG C NE  1 
ATOM   6917 C CZ  . ARG C 1 317 ? 114.660 158.110 135.758 1.00 57.97  ? 391 ARG C CZ  1 
ATOM   6918 N NH1 . ARG C 1 317 ? 115.721 158.886 135.908 1.00 55.64  ? 391 ARG C NH1 1 
ATOM   6919 N NH2 . ARG C 1 317 ? 113.445 158.641 135.867 1.00 58.42  ? 391 ARG C NH2 1 
ATOM   6920 N N   . HIS C 1 318 ? 115.538 152.606 139.375 1.00 46.14  ? 392 HIS C N   1 
ATOM   6921 C CA  . HIS C 1 318 ? 115.131 151.715 140.457 1.00 52.11  ? 392 HIS C CA  1 
ATOM   6922 C C   . HIS C 1 318 ? 113.624 151.737 140.685 1.00 52.96  ? 392 HIS C C   1 
ATOM   6923 O O   . HIS C 1 318 ? 113.049 150.732 141.117 1.00 55.68  ? 392 HIS C O   1 
ATOM   6924 C CB  . HIS C 1 318 ? 115.862 152.092 141.746 1.00 50.83  ? 392 HIS C CB  1 
ATOM   6925 C CG  . HIS C 1 318 ? 117.267 151.582 141.813 1.00 52.31  ? 392 HIS C CG  1 
ATOM   6926 N ND1 . HIS C 1 318 ? 118.334 152.271 141.279 1.00 57.45  ? 392 HIS C ND1 1 
ATOM   6927 C CD2 . HIS C 1 318 ? 117.781 150.451 142.350 1.00 52.81  ? 392 HIS C CD2 1 
ATOM   6928 C CE1 . HIS C 1 318 ? 119.445 151.587 141.484 1.00 57.03  ? 392 HIS C CE1 1 
ATOM   6929 N NE2 . HIS C 1 318 ? 119.137 150.478 142.132 1.00 56.08  ? 392 HIS C NE2 1 
ATOM   6930 N N   . GLY C 1 319 ? 112.971 152.859 140.407 1.00 48.38  ? 393 GLY C N   1 
ATOM   6931 C CA  . GLY C 1 319 ? 111.545 152.988 140.618 1.00 52.98  ? 393 GLY C CA  1 
ATOM   6932 C C   . GLY C 1 319 ? 110.671 152.582 139.453 1.00 57.88  ? 393 GLY C C   1 
ATOM   6933 O O   . GLY C 1 319 ? 109.454 152.785 139.511 1.00 57.97  ? 393 GLY C O   1 
ATOM   6934 N N   . ASP C 1 320 ? 111.245 152.015 138.397 1.00 54.38  ? 394 ASP C N   1 
ATOM   6935 C CA  . ASP C 1 320 ? 110.512 151.674 137.188 1.00 45.14  ? 394 ASP C CA  1 
ATOM   6936 C C   . ASP C 1 320 ? 110.273 150.171 137.120 1.00 46.50  ? 394 ASP C C   1 
ATOM   6937 O O   . ASP C 1 320 ? 111.047 149.378 137.663 1.00 53.76  ? 394 ASP C O   1 
ATOM   6938 C CB  . ASP C 1 320 ? 111.272 152.141 135.943 1.00 50.85  ? 394 ASP C CB  1 
ATOM   6939 C CG  . ASP C 1 320 ? 111.473 153.644 135.916 1.00 56.49  ? 394 ASP C CG  1 
ATOM   6940 O OD1 . ASP C 1 320 ? 110.628 154.367 136.479 1.00 58.21  ? 394 ASP C OD1 1 
ATOM   6941 O OD2 . ASP C 1 320 ? 112.484 154.104 135.346 1.00 57.21  ? 394 ASP C OD2 1 
ATOM   6942 N N   . SER C 1 321 ? 109.190 149.786 136.447 1.00 37.87  ? 395 SER C N   1 
ATOM   6943 C CA  . SER C 1 321 ? 108.820 148.384 136.317 1.00 36.74  ? 395 SER C CA  1 
ATOM   6944 C C   . SER C 1 321 ? 108.329 148.109 134.904 1.00 37.83  ? 395 SER C C   1 
ATOM   6945 O O   . SER C 1 321 ? 107.766 148.987 134.244 1.00 43.81  ? 395 SER C O   1 
ATOM   6946 C CB  . SER C 1 321 ? 107.737 147.990 137.327 1.00 39.58  ? 395 SER C CB  1 
ATOM   6947 O OG  . SER C 1 321 ? 106.516 148.654 137.051 1.00 43.48  ? 395 SER C OG  1 
ATOM   6948 N N   . ILE C 1 322 ? 108.545 146.876 134.446 1.00 32.30  ? 396 ILE C N   1 
ATOM   6949 C CA  . ILE C 1 322 ? 108.090 146.429 133.133 1.00 28.17  ? 396 ILE C CA  1 
ATOM   6950 C C   . ILE C 1 322 ? 107.203 145.210 133.335 1.00 30.96  ? 396 ILE C C   1 
ATOM   6951 O O   . ILE C 1 322 ? 107.637 144.216 133.925 1.00 38.19  ? 396 ILE C O   1 
ATOM   6952 C CB  . ILE C 1 322 ? 109.273 146.101 132.209 1.00 23.90  ? 396 ILE C CB  1 
ATOM   6953 C CG1 . ILE C 1 322 ? 110.103 147.357 131.940 1.00 26.79  ? 396 ILE C CG1 1 
ATOM   6954 C CG2 . ILE C 1 322 ? 108.784 145.487 130.911 1.00 28.03  ? 396 ILE C CG2 1 
ATOM   6955 C CD1 . ILE C 1 322 ? 111.431 147.078 131.283 1.00 32.62  ? 396 ILE C CD1 1 
ATOM   6956 N N   . SER C 1 323 ? 105.971 145.275 132.838 1.00 25.32  ? 397 SER C N   1 
ATOM   6957 C CA  . SER C 1 323 ? 105.007 144.191 132.980 1.00 18.78  ? 397 SER C CA  1 
ATOM   6958 C C   . SER C 1 323 ? 104.703 143.601 131.611 1.00 25.83  ? 397 SER C C   1 
ATOM   6959 O O   . SER C 1 323 ? 104.306 144.326 130.694 1.00 38.45  ? 397 SER C O   1 
ATOM   6960 C CB  . SER C 1 323 ? 103.720 144.685 133.643 1.00 33.66  ? 397 SER C CB  1 
ATOM   6961 O OG  . SER C 1 323 ? 103.967 145.133 134.964 1.00 42.14  ? 397 SER C OG  1 
ATOM   6962 N N   . ILE C 1 324 ? 104.882 142.290 131.479 1.00 24.07  ? 398 ILE C N   1 
ATOM   6963 C CA  . ILE C 1 324 ? 104.764 141.591 130.205 1.00 19.87  ? 398 ILE C CA  1 
ATOM   6964 C C   . ILE C 1 324 ? 103.725 140.487 130.341 1.00 19.20  ? 398 ILE C C   1 
ATOM   6965 O O   . ILE C 1 324 ? 103.788 139.678 131.274 1.00 35.04  ? 398 ILE C O   1 
ATOM   6966 C CB  . ILE C 1 324 ? 106.116 141.011 129.750 1.00 17.13  ? 398 ILE C CB  1 
ATOM   6967 C CG1 . ILE C 1 324 ? 107.186 142.103 129.734 1.00 24.89  ? 398 ILE C CG1 1 
ATOM   6968 C CG2 . ILE C 1 324 ? 105.986 140.365 128.381 1.00 27.52  ? 398 ILE C CG2 1 
ATOM   6969 C CD1 . ILE C 1 324 ? 108.592 141.579 129.857 1.00 27.48  ? 398 ILE C CD1 1 
ATOM   6970 N N   . THR C 1 325 ? 102.775 140.457 129.408 1.00 28.20  ? 399 THR C N   1 
ATOM   6971 C CA  . THR C 1 325 ? 101.764 139.411 129.330 1.00 25.85  ? 399 THR C CA  1 
ATOM   6972 C C   . THR C 1 325 ? 101.592 139.020 127.868 1.00 30.20  ? 399 THR C C   1 
ATOM   6973 O O   . THR C 1 325 ? 102.189 139.621 126.972 1.00 38.66  ? 399 THR C O   1 
ATOM   6974 C CB  . THR C 1 325 ? 100.431 139.869 129.936 1.00 28.33  ? 399 THR C CB  1 
ATOM   6975 O OG1 . THR C 1 325 ? 100.148 141.210 129.518 1.00 34.11  ? 399 THR C OG1 1 
ATOM   6976 C CG2 . THR C 1 325 ? 100.485 139.815 131.454 1.00 33.33  ? 399 THR C CG2 1 
ATOM   6977 N N   . THR C 1 326 ? 100.764 138.009 127.621 1.00 30.74  ? 400 THR C N   1 
ATOM   6978 C CA  . THR C 1 326 ? 100.462 137.586 126.260 1.00 21.38  ? 400 THR C CA  1 
ATOM   6979 C C   . THR C 1 326 ? 99.285  138.391 125.725 1.00 29.17  ? 400 THR C C   1 
ATOM   6980 O O   . THR C 1 326 ? 98.207  138.402 126.327 1.00 40.15  ? 400 THR C O   1 
ATOM   6981 C CB  . THR C 1 326 ? 100.148 136.091 126.205 1.00 28.54  ? 400 THR C CB  1 
ATOM   6982 O OG1 . THR C 1 326 ? 101.284 135.345 126.657 1.00 35.19  ? 400 THR C OG1 1 
ATOM   6983 C CG2 . THR C 1 326 ? 99.811  135.673 124.784 1.00 29.68  ? 400 THR C CG2 1 
ATOM   6984 N N   . SER C 1 327 ? 99.497  139.060 124.596 1.00 26.81  ? 401 SER C N   1 
ATOM   6985 C CA  . SER C 1 327 ? 98.474  139.924 124.027 1.00 26.46  ? 401 SER C CA  1 
ATOM   6986 C C   . SER C 1 327 ? 97.325  139.105 123.451 1.00 35.30  ? 401 SER C C   1 
ATOM   6987 O O   . SER C 1 327 ? 97.500  137.969 123.003 1.00 40.98  ? 401 SER C O   1 
ATOM   6988 C CB  . SER C 1 327 ? 99.075  140.815 122.941 1.00 31.56  ? 401 SER C CB  1 
ATOM   6989 O OG  . SER C 1 327 ? 98.219  141.905 122.645 1.00 42.52  ? 401 SER C OG  1 
ATOM   6990 N N   . THR C 1 328 ? 96.135  139.701 123.467 1.00 32.80  ? 402 THR C N   1 
ATOM   6991 C CA  . THR C 1 328 ? 94.941  139.089 122.902 1.00 30.92  ? 402 THR C CA  1 
ATOM   6992 C C   . THR C 1 328 ? 94.776  139.381 121.417 1.00 37.84  ? 402 THR C C   1 
ATOM   6993 O O   . THR C 1 328 ? 93.804  138.917 120.813 1.00 38.95  ? 402 THR C O   1 
ATOM   6994 C CB  . THR C 1 328 ? 93.695  139.562 123.656 1.00 31.58  ? 402 THR C CB  1 
ATOM   6995 O OG1 . THR C 1 328 ? 93.572  140.984 123.533 1.00 31.73  ? 402 THR C OG1 1 
ATOM   6996 C CG2 . THR C 1 328 ? 93.793  139.194 125.127 1.00 34.31  ? 402 THR C CG2 1 
ATOM   6997 N N   . TYR C 1 329 ? 95.697  140.137 120.818 1.00 38.58  ? 403 TYR C N   1 
ATOM   6998 C CA  . TYR C 1 329 ? 95.641  140.507 119.404 1.00 30.25  ? 403 TYR C CA  1 
ATOM   6999 C C   . TYR C 1 329 ? 96.853  139.913 118.701 1.00 30.46  ? 403 TYR C C   1 
ATOM   7000 O O   . TYR C 1 329 ? 97.935  140.521 118.686 1.00 37.43  ? 403 TYR C O   1 
ATOM   7001 C CB  . TYR C 1 329 ? 95.600  142.024 119.238 1.00 30.03  ? 403 TYR C CB  1 
ATOM   7002 C CG  . TYR C 1 329 ? 94.456  142.692 119.965 1.00 32.12  ? 403 TYR C CG  1 
ATOM   7003 C CD1 . TYR C 1 329 ? 93.150  142.252 119.799 1.00 36.25  ? 403 TYR C CD1 1 
ATOM   7004 C CD2 . TYR C 1 329 ? 94.683  143.759 120.823 1.00 35.70  ? 403 TYR C CD2 1 
ATOM   7005 C CE1 . TYR C 1 329 ? 92.102  142.860 120.462 1.00 35.58  ? 403 TYR C CE1 1 
ATOM   7006 C CE2 . TYR C 1 329 ? 93.642  144.372 121.490 1.00 31.09  ? 403 TYR C CE2 1 
ATOM   7007 C CZ  . TYR C 1 329 ? 92.354  143.919 121.306 1.00 33.14  ? 403 TYR C CZ  1 
ATOM   7008 O OH  . TYR C 1 329 ? 91.314  144.527 121.970 1.00 37.76  ? 403 TYR C OH  1 
ATOM   7009 N N   . PRO C 1 330 ? 96.722  138.735 118.107 1.00 22.35  ? 404 PRO C N   1 
ATOM   7010 C CA  . PRO C 1 330 ? 97.845  138.111 117.404 1.00 25.94  ? 404 PRO C CA  1 
ATOM   7011 C C   . PRO C 1 330 ? 98.071  138.765 116.044 1.00 32.19  ? 404 PRO C C   1 
ATOM   7012 O O   . PRO C 1 330 ? 97.319  139.633 115.606 1.00 39.93  ? 404 PRO C O   1 
ATOM   7013 C CB  . PRO C 1 330 ? 97.395  136.657 117.260 1.00 30.84  ? 404 PRO C CB  1 
ATOM   7014 C CG  . PRO C 1 330 ? 95.912  136.741 117.212 1.00 31.55  ? 404 PRO C CG  1 
ATOM   7015 C CD  . PRO C 1 330 ? 95.542  137.854 118.151 1.00 28.18  ? 404 PRO C CD  1 
ATOM   7016 N N   . LEU C 1 331 ? 99.137  138.326 115.377 1.00 28.96  ? 405 LEU C N   1 
ATOM   7017 C CA  . LEU C 1 331 ? 99.470  138.793 114.034 1.00 16.73  ? 405 LEU C CA  1 
ATOM   7018 C C   . LEU C 1 331 ? 99.187  137.684 113.031 1.00 31.75  ? 405 LEU C C   1 
ATOM   7019 O O   . LEU C 1 331 ? 99.964  136.722 112.935 1.00 40.64  ? 405 LEU C O   1 
ATOM   7020 C CB  . LEU C 1 331 ? 100.939 139.216 113.959 1.00 27.90  ? 405 LEU C CB  1 
ATOM   7021 C CG  . LEU C 1 331 ? 101.425 139.741 112.605 1.00 25.70  ? 405 LEU C CG  1 
ATOM   7022 C CD1 . LEU C 1 331 ? 100.762 141.055 112.262 1.00 27.95  ? 405 LEU C CD1 1 
ATOM   7023 C CD2 . LEU C 1 331 ? 102.933 139.882 112.581 1.00 29.97  ? 405 LEU C CD2 1 
ATOM   7024 N N   . PRO C 1 332 ? 98.101  137.763 112.264 1.00 29.33  ? 406 PRO C N   1 
ATOM   7025 C CA  . PRO C 1 332 ? 97.842  136.728 111.255 1.00 22.37  ? 406 PRO C CA  1 
ATOM   7026 C C   . PRO C 1 332 ? 98.752  136.860 110.046 1.00 29.05  ? 406 PRO C C   1 
ATOM   7027 O O   . PRO C 1 332 ? 98.627  137.806 109.262 1.00 41.02  ? 406 PRO C O   1 
ATOM   7028 C CB  . PRO C 1 332 ? 96.372  136.961 110.886 1.00 29.76  ? 406 PRO C CB  1 
ATOM   7029 C CG  . PRO C 1 332 ? 96.133  138.398 111.200 1.00 26.70  ? 406 PRO C CG  1 
ATOM   7030 C CD  . PRO C 1 332 ? 96.971  138.697 112.405 1.00 30.75  ? 406 PRO C CD  1 
ATOM   7031 N N   . SER C 1 333 ? 99.670  135.912 109.885 1.00 26.20  ? 407 SER C N   1 
ATOM   7032 C CA  . SER C 1 333 ? 100.613 135.899 108.774 1.00 23.25  ? 407 SER C CA  1 
ATOM   7033 C C   . SER C 1 333 ? 100.200 134.808 107.796 1.00 29.98  ? 407 SER C C   1 
ATOM   7034 O O   . SER C 1 333 ? 100.109 133.634 108.172 1.00 40.99  ? 407 SER C O   1 
ATOM   7035 C CB  . SER C 1 333 ? 102.040 135.669 109.269 1.00 27.99  ? 407 SER C CB  1 
ATOM   7036 O OG  . SER C 1 333 ? 102.290 134.291 109.480 1.00 38.42  ? 407 SER C OG  1 
ATOM   7037 N N   . ILE C 1 334 ? 99.954  135.196 106.550 1.00 27.81  ? 408 ILE C N   1 
ATOM   7038 C CA  . ILE C 1 334 ? 99.508  134.257 105.529 1.00 25.11  ? 408 ILE C CA  1 
ATOM   7039 C C   . ILE C 1 334 ? 100.690 133.411 105.078 1.00 34.48  ? 408 ILE C C   1 
ATOM   7040 O O   . ILE C 1 334 ? 101.766 133.936 104.767 1.00 44.53  ? 408 ILE C O   1 
ATOM   7041 C CB  . ILE C 1 334 ? 98.871  135.003 104.348 1.00 25.59  ? 408 ILE C CB  1 
ATOM   7042 C CG1 . ILE C 1 334 ? 97.869  136.038 104.862 1.00 28.72  ? 408 ILE C CG1 1 
ATOM   7043 C CG2 . ILE C 1 334 ? 98.195  134.026 103.402 1.00 35.36  ? 408 ILE C CG2 1 
ATOM   7044 C CD1 . ILE C 1 334 ? 97.294  136.921 103.787 1.00 31.88  ? 408 ILE C CD1 1 
ATOM   7045 N N   . CYS C 1 335 ? 100.492 132.098 105.040 1.00 30.79  ? 409 CYS C N   1 
ATOM   7046 C CA  . CYS C 1 335 ? 101.531 131.149 104.672 1.00 30.28  ? 409 CYS C CA  1 
ATOM   7047 C C   . CYS C 1 335 ? 101.324 130.671 103.241 1.00 39.59  ? 409 CYS C C   1 
ATOM   7048 O O   . CYS C 1 335 ? 100.197 130.626 102.740 1.00 42.81  ? 409 CYS C O   1 
ATOM   7049 C CB  . CYS C 1 335 ? 101.534 129.957 105.629 1.00 38.33  ? 409 CYS C CB  1 
ATOM   7050 S SG  . CYS C 1 335 ? 100.035 128.956 105.569 1.00 56.71  ? 409 CYS C SG  1 
ATOM   7051 N N   . VAL C 1 336 ? 102.429 130.317 102.579 1.00 40.79  ? 410 VAL C N   1 
ATOM   7052 C CA  . VAL C 1 336 ? 102.347 129.928 101.174 1.00 33.40  ? 410 VAL C CA  1 
ATOM   7053 C C   . VAL C 1 336 ? 101.609 128.601 101.022 1.00 38.76  ? 410 VAL C C   1 
ATOM   7054 O O   . VAL C 1 336 ? 100.680 128.484 100.213 1.00 45.83  ? 410 VAL C O   1 
ATOM   7055 C CB  . VAL C 1 336 ? 103.749 129.885 100.535 1.00 31.22  ? 410 VAL C CB  1 
ATOM   7056 C CG1 . VAL C 1 336 ? 104.265 131.296 100.309 1.00 38.34  ? 410 VAL C CG1 1 
ATOM   7057 C CG2 . VAL C 1 336 ? 104.724 129.110 101.398 1.00 39.17  ? 410 VAL C CG2 1 
ATOM   7058 N N   . ARG C 1 337 ? 102.002 127.582 101.786 1.00 38.79  ? 411 ARG C N   1 
ATOM   7059 C CA  . ARG C 1 337 ? 101.302 126.303 101.736 1.00 42.96  ? 411 ARG C CA  1 
ATOM   7060 C C   . ARG C 1 337 ? 100.757 125.851 103.082 1.00 45.53  ? 411 ARG C C   1 
ATOM   7061 O O   . ARG C 1 337 ? 99.576  125.490 103.168 1.00 51.62  ? 411 ARG C O   1 
ATOM   7062 C CB  . ARG C 1 337 ? 102.213 125.228 101.111 1.00 43.96  ? 411 ARG C CB  1 
ATOM   7063 C CG  . ARG C 1 337 ? 103.501 124.909 101.845 1.00 43.62  ? 411 ARG C CG  1 
ATOM   7064 C CD  . ARG C 1 337 ? 104.324 123.938 101.011 1.00 47.56  ? 411 ARG C CD  1 
ATOM   7065 N NE  . ARG C 1 337 ? 105.556 123.520 101.668 1.00 52.90  ? 411 ARG C NE  1 
ATOM   7066 C CZ  . ARG C 1 337 ? 106.707 124.171 101.580 1.00 51.53  ? 411 ARG C CZ  1 
ATOM   7067 N NH1 . ARG C 1 337 ? 106.818 125.289 100.881 1.00 50.14  ? 411 ARG C NH1 1 
ATOM   7068 N NH2 . ARG C 1 337 ? 107.776 123.687 102.205 1.00 51.11  ? 411 ARG C NH2 1 
ATOM   7069 N N   . ASP C 1 338 ? 101.561 125.870 104.139 1.00 40.98  ? 412 ASP C N   1 
ATOM   7070 C CA  . ASP C 1 338 ? 101.104 125.492 105.471 1.00 42.41  ? 412 ASP C CA  1 
ATOM   7071 C C   . ASP C 1 338 ? 102.150 125.944 106.495 1.00 43.72  ? 412 ASP C C   1 
ATOM   7072 O O   . ASP C 1 338 ? 103.290 126.236 106.125 1.00 46.41  ? 412 ASP C O   1 
ATOM   7073 C CB  . ASP C 1 338 ? 100.817 123.976 105.563 1.00 40.69  ? 412 ASP C CB  1 
ATOM   7074 C CG  . ASP C 1 338 ? 102.068 123.111 105.519 1.00 47.94  ? 412 ASP C CG  1 
ATOM   7075 O OD1 . ASP C 1 338 ? 103.193 123.636 105.467 1.00 51.84  ? 412 ASP C OD1 1 
ATOM   7076 O OD2 . ASP C 1 338 ? 101.914 121.872 105.497 1.00 47.08  ? 412 ASP C OD2 1 
ATOM   7077 N N   . PRO C 1 339 ? 101.772 126.037 107.775 1.00 37.34  ? 413 PRO C N   1 
ATOM   7078 C CA  . PRO C 1 339 ? 102.721 126.573 108.772 1.00 36.99  ? 413 PRO C CA  1 
ATOM   7079 C C   . PRO C 1 339 ? 103.990 125.752 108.942 1.00 40.52  ? 413 PRO C C   1 
ATOM   7080 O O   . PRO C 1 339 ? 105.092 126.318 108.954 1.00 47.80  ? 413 PRO C O   1 
ATOM   7081 C CB  . PRO C 1 339 ? 101.887 126.596 110.060 1.00 37.20  ? 413 PRO C CB  1 
ATOM   7082 C CG  . PRO C 1 339 ? 100.481 126.661 109.607 1.00 40.62  ? 413 PRO C CG  1 
ATOM   7083 C CD  . PRO C 1 339 ? 100.414 125.892 108.330 1.00 38.07  ? 413 PRO C CD  1 
ATOM   7084 N N   . VAL C 1 340 ? 103.867 124.431 109.083 1.00 35.83  ? 414 VAL C N   1 
ATOM   7085 C CA  . VAL C 1 340 ? 105.009 123.611 109.481 1.00 36.01  ? 414 VAL C CA  1 
ATOM   7086 C C   . VAL C 1 340 ? 106.080 123.604 108.398 1.00 38.30  ? 414 VAL C C   1 
ATOM   7087 O O   . VAL C 1 340 ? 107.272 123.787 108.679 1.00 43.76  ? 414 VAL C O   1 
ATOM   7088 C CB  . VAL C 1 340 ? 104.549 122.182 109.820 1.00 39.63  ? 414 VAL C CB  1 
ATOM   7089 C CG1 . VAL C 1 340 ? 105.736 121.346 110.251 1.00 42.72  ? 414 VAL C CG1 1 
ATOM   7090 C CG2 . VAL C 1 340 ? 103.487 122.209 110.906 1.00 36.44  ? 414 VAL C CG2 1 
ATOM   7091 N N   . SER C 1 341 ? 105.679 123.368 107.148 1.00 33.22  ? 415 SER C N   1 
ATOM   7092 C CA  . SER C 1 341 ? 106.659 123.295 106.070 1.00 32.84  ? 415 SER C CA  1 
ATOM   7093 C C   . SER C 1 341 ? 107.332 124.641 105.845 1.00 35.90  ? 415 SER C C   1 
ATOM   7094 O O   . SER C 1 341 ? 108.534 124.697 105.570 1.00 45.66  ? 415 SER C O   1 
ATOM   7095 C CB  . SER C 1 341 ? 106.002 122.796 104.785 1.00 37.27  ? 415 SER C CB  1 
ATOM   7096 O OG  . SER C 1 341 ? 105.181 121.670 105.037 1.00 43.76  ? 415 SER C OG  1 
ATOM   7097 N N   . ASP C 1 342 ? 106.576 125.736 105.954 1.00 31.28  ? 416 ASP C N   1 
ATOM   7098 C CA  . ASP C 1 342 ? 107.181 127.058 105.829 1.00 36.66  ? 416 ASP C CA  1 
ATOM   7099 C C   . ASP C 1 342 ? 108.179 127.318 106.950 1.00 39.36  ? 416 ASP C C   1 
ATOM   7100 O O   . ASP C 1 342 ? 109.265 127.859 106.711 1.00 43.78  ? 416 ASP C O   1 
ATOM   7101 C CB  . ASP C 1 342 ? 106.100 128.136 105.818 1.00 38.43  ? 416 ASP C CB  1 
ATOM   7102 C CG  . ASP C 1 342 ? 105.161 128.001 104.643 1.00 48.94  ? 416 ASP C CG  1 
ATOM   7103 O OD1 . ASP C 1 342 ? 105.352 127.069 103.833 1.00 50.90  ? 416 ASP C OD1 1 
ATOM   7104 O OD2 . ASP C 1 342 ? 104.233 128.826 104.528 1.00 46.92  ? 416 ASP C OD2 1 
ATOM   7105 N N   . TRP C 1 343 ? 107.832 126.932 108.181 1.00 36.70  ? 417 TRP C N   1 
ATOM   7106 C CA  . TRP C 1 343 ? 108.753 127.111 109.298 1.00 31.79  ? 417 TRP C CA  1 
ATOM   7107 C C   . TRP C 1 343 ? 110.036 126.317 109.088 1.00 33.41  ? 417 TRP C C   1 
ATOM   7108 O O   . TRP C 1 343 ? 111.140 126.826 109.322 1.00 38.98  ? 417 TRP C O   1 
ATOM   7109 C CB  . TRP C 1 343 ? 108.075 126.698 110.605 1.00 34.34  ? 417 TRP C CB  1 
ATOM   7110 C CG  . TRP C 1 343 ? 108.834 127.097 111.832 1.00 35.00  ? 417 TRP C CG  1 
ATOM   7111 C CD1 . TRP C 1 343 ? 109.125 128.365 112.239 1.00 32.48  ? 417 TRP C CD1 1 
ATOM   7112 C CD2 . TRP C 1 343 ? 109.399 126.220 112.814 1.00 39.53  ? 417 TRP C CD2 1 
ATOM   7113 N NE1 . TRP C 1 343 ? 109.836 128.333 113.413 1.00 35.28  ? 417 TRP C NE1 1 
ATOM   7114 C CE2 . TRP C 1 343 ? 110.017 127.028 113.787 1.00 35.78  ? 417 TRP C CE2 1 
ATOM   7115 C CE3 . TRP C 1 343 ? 109.441 124.831 112.964 1.00 38.79  ? 417 TRP C CE3 1 
ATOM   7116 C CZ2 . TRP C 1 343 ? 110.671 126.493 114.894 1.00 35.05  ? 417 TRP C CZ2 1 
ATOM   7117 C CZ3 . TRP C 1 343 ? 110.088 124.303 114.063 1.00 32.61  ? 417 TRP C CZ3 1 
ATOM   7118 C CH2 . TRP C 1 343 ? 110.695 125.132 115.013 1.00 33.11  ? 417 TRP C CH2 1 
ATOM   7119 N N   . PHE C 1 344 ? 109.914 125.070 108.630 1.00 34.64  ? 418 PHE C N   1 
ATOM   7120 C CA  . PHE C 1 344 ? 111.107 124.252 108.443 1.00 27.13  ? 418 PHE C CA  1 
ATOM   7121 C C   . PHE C 1 344 ? 111.932 124.714 107.247 1.00 30.58  ? 418 PHE C C   1 
ATOM   7122 O O   . PHE C 1 344 ? 113.165 124.639 107.285 1.00 38.87  ? 418 PHE C O   1 
ATOM   7123 C CB  . PHE C 1 344 ? 110.724 122.780 108.312 1.00 26.88  ? 418 PHE C CB  1 
ATOM   7124 C CG  . PHE C 1 344 ? 110.558 122.087 109.633 1.00 34.66  ? 418 PHE C CG  1 
ATOM   7125 C CD1 . PHE C 1 344 ? 111.651 121.550 110.291 1.00 34.53  ? 418 PHE C CD1 1 
ATOM   7126 C CD2 . PHE C 1 344 ? 109.311 121.981 110.224 1.00 36.93  ? 418 PHE C CD2 1 
ATOM   7127 C CE1 . PHE C 1 344 ? 111.502 120.918 111.509 1.00 34.93  ? 418 PHE C CE1 1 
ATOM   7128 C CE2 . PHE C 1 344 ? 109.157 121.349 111.441 1.00 32.13  ? 418 PHE C CE2 1 
ATOM   7129 C CZ  . PHE C 1 344 ? 110.253 120.817 112.084 1.00 32.48  ? 418 PHE C CZ  1 
ATOM   7130 N N   . GLU C 1 345 ? 111.285 125.207 106.187 1.00 27.38  ? 419 GLU C N   1 
ATOM   7131 C CA  . GLU C 1 345 ? 112.033 125.801 105.085 1.00 25.91  ? 419 GLU C CA  1 
ATOM   7132 C C   . GLU C 1 345 ? 112.774 127.051 105.535 1.00 34.41  ? 419 GLU C C   1 
ATOM   7133 O O   . GLU C 1 345 ? 113.909 127.292 105.112 1.00 40.75  ? 419 GLU C O   1 
ATOM   7134 C CB  . GLU C 1 345 ? 111.104 126.123 103.916 1.00 30.74  ? 419 GLU C CB  1 
ATOM   7135 C CG  . GLU C 1 345 ? 110.853 124.952 102.984 1.00 41.46  ? 419 GLU C CG  1 
ATOM   7136 C CD  . GLU C 1 345 ? 110.403 125.394 101.606 1.00 45.76  ? 419 GLU C CD  1 
ATOM   7137 O OE1 . GLU C 1 345 ? 110.844 126.472 101.155 1.00 43.98  ? 419 GLU C OE1 1 
ATOM   7138 O OE2 . GLU C 1 345 ? 109.618 124.661 100.969 1.00 46.39  ? 419 GLU C OE2 1 
ATOM   7139 N N   . SER C 1 346 ? 112.145 127.866 106.384 1.00 34.74  ? 420 SER C N   1 
ATOM   7140 C CA  . SER C 1 346 ? 112.834 129.030 106.928 1.00 27.71  ? 420 SER C CA  1 
ATOM   7141 C C   . SER C 1 346 ? 114.038 128.611 107.761 1.00 31.94  ? 420 SER C C   1 
ATOM   7142 O O   . SER C 1 346 ? 115.112 129.214 107.658 1.00 35.54  ? 420 SER C O   1 
ATOM   7143 C CB  . SER C 1 346 ? 111.867 129.870 107.761 1.00 30.62  ? 420 SER C CB  1 
ATOM   7144 O OG  . SER C 1 346 ? 110.825 130.395 106.957 1.00 35.75  ? 420 SER C OG  1 
ATOM   7145 N N   . LEU C 1 347 ? 113.879 127.572 108.584 1.00 35.78  ? 421 LEU C N   1 
ATOM   7146 C CA  . LEU C 1 347 ? 115.008 127.068 109.363 1.00 33.39  ? 421 LEU C CA  1 
ATOM   7147 C C   . LEU C 1 347 ? 116.133 126.577 108.458 1.00 35.97  ? 421 LEU C C   1 
ATOM   7148 O O   . LEU C 1 347 ? 117.312 126.838 108.724 1.00 45.10  ? 421 LEU C O   1 
ATOM   7149 C CB  . LEU C 1 347 ? 114.552 125.946 110.295 1.00 34.88  ? 421 LEU C CB  1 
ATOM   7150 C CG  . LEU C 1 347 ? 113.650 126.308 111.475 1.00 30.27  ? 421 LEU C CG  1 
ATOM   7151 C CD1 . LEU C 1 347 ? 113.179 125.051 112.182 1.00 32.73  ? 421 LEU C CD1 1 
ATOM   7152 C CD2 . LEU C 1 347 ? 114.389 127.213 112.441 1.00 36.15  ? 421 LEU C CD2 1 
ATOM   7153 N N   . ALA C 1 348 ? 115.788 125.862 107.385 1.00 33.58  ? 422 ALA C N   1 
ATOM   7154 C CA  . ALA C 1 348 ? 116.811 125.289 106.516 1.00 26.83  ? 422 ALA C CA  1 
ATOM   7155 C C   . ALA C 1 348 ? 117.501 126.345 105.661 1.00 27.68  ? 422 ALA C C   1 
ATOM   7156 O O   . ALA C 1 348 ? 118.693 126.212 105.363 1.00 40.96  ? 422 ALA C O   1 
ATOM   7157 C CB  . ALA C 1 348 ? 116.196 124.210 105.625 1.00 31.54  ? 422 ALA C CB  1 
ATOM   7158 N N   . GLN C 1 349 ? 116.782 127.392 105.258 1.00 30.25  ? 423 GLN C N   1 
ATOM   7159 C CA  . GLN C 1 349 ? 117.326 128.363 104.317 1.00 26.91  ? 423 GLN C CA  1 
ATOM   7160 C C   . GLN C 1 349 ? 117.989 129.550 105.004 1.00 28.71  ? 423 GLN C C   1 
ATOM   7161 O O   . GLN C 1 349 ? 119.032 130.023 104.543 1.00 39.61  ? 423 GLN C O   1 
ATOM   7162 C CB  . GLN C 1 349 ? 116.218 128.859 103.384 1.00 30.37  ? 423 GLN C CB  1 
ATOM   7163 C CG  . GLN C 1 349 ? 116.058 128.034 102.119 1.00 34.81  ? 423 GLN C CG  1 
ATOM   7164 C CD  . GLN C 1 349 ? 115.025 128.613 101.172 1.00 42.19  ? 423 GLN C CD  1 
ATOM   7165 O OE1 . GLN C 1 349 ? 114.276 129.520 101.533 1.00 45.14  ? 423 GLN C OE1 1 
ATOM   7166 N NE2 . GLN C 1 349 ? 114.982 128.090 99.952  1.00 40.96  ? 423 GLN C NE2 1 
ATOM   7167 N N   . CYS C 1 350 ? 117.407 130.049 106.093 1.00 38.69  ? 424 CYS C N   1 
ATOM   7168 C CA  . CYS C 1 350 ? 117.945 131.222 106.768 1.00 39.16  ? 424 CYS C CA  1 
ATOM   7169 C C   . CYS C 1 350 ? 118.967 130.852 107.837 1.00 41.70  ? 424 CYS C C   1 
ATOM   7170 O O   . CYS C 1 350 ? 120.090 131.365 107.830 1.00 47.51  ? 424 CYS C O   1 
ATOM   7171 C CB  . CYS C 1 350 ? 116.805 132.037 107.388 1.00 37.09  ? 424 CYS C CB  1 
ATOM   7172 S SG  . CYS C 1 350 ? 115.649 132.740 106.192 1.00 55.66  ? 424 CYS C SG  1 
ATOM   7173 N N   . LEU C 1 351 ? 118.594 129.969 108.760 1.00 37.67  ? 425 LEU C N   1 
ATOM   7174 C CA  . LEU C 1 351 ? 119.452 129.621 109.884 1.00 31.21  ? 425 LEU C CA  1 
ATOM   7175 C C   . LEU C 1 351 ? 120.339 128.412 109.618 1.00 35.88  ? 425 LEU C C   1 
ATOM   7176 O O   . LEU C 1 351 ? 121.201 128.109 110.450 1.00 43.83  ? 425 LEU C O   1 
ATOM   7177 C CB  . LEU C 1 351 ? 118.601 129.364 111.131 1.00 34.44  ? 425 LEU C CB  1 
ATOM   7178 C CG  . LEU C 1 351 ? 118.141 130.607 111.893 1.00 34.29  ? 425 LEU C CG  1 
ATOM   7179 C CD1 . LEU C 1 351 ? 117.207 130.223 113.027 1.00 37.02  ? 425 LEU C CD1 1 
ATOM   7180 C CD2 . LEU C 1 351 ? 119.335 131.389 112.417 1.00 38.56  ? 425 LEU C CD2 1 
ATOM   7181 N N   . HIS C 1 352 ? 120.158 127.729 108.487 1.00 33.16  ? 426 HIS C N   1 
ATOM   7182 C CA  . HIS C 1 352 ? 120.934 126.536 108.143 1.00 28.29  ? 426 HIS C CA  1 
ATOM   7183 C C   . HIS C 1 352 ? 120.877 125.500 109.263 1.00 32.20  ? 426 HIS C C   1 
ATOM   7184 O O   . HIS C 1 352 ? 121.897 124.998 109.739 1.00 45.15  ? 426 HIS C O   1 
ATOM   7185 C CB  . HIS C 1 352 ? 122.378 126.902 107.798 1.00 34.39  ? 426 HIS C CB  1 
ATOM   7186 C CG  . HIS C 1 352 ? 122.496 127.964 106.751 1.00 38.48  ? 426 HIS C CG  1 
ATOM   7187 N ND1 . HIS C 1 352 ? 122.638 127.673 105.412 1.00 32.99  ? 426 HIS C ND1 1 
ATOM   7188 C CD2 . HIS C 1 352 ? 122.487 129.314 106.844 1.00 38.54  ? 426 HIS C CD2 1 
ATOM   7189 C CE1 . HIS C 1 352 ? 122.715 128.798 104.725 1.00 34.00  ? 426 HIS C CE1 1 
ATOM   7190 N NE2 . HIS C 1 352 ? 122.626 129.809 105.571 1.00 38.56  ? 426 HIS C NE2 1 
ATOM   7191 N N   . TRP C 1 353 ? 119.657 125.182 109.683 1.00 29.08  ? 427 TRP C N   1 
ATOM   7192 C CA  . TRP C 1 353 ? 119.427 124.245 110.776 1.00 24.27  ? 427 TRP C CA  1 
ATOM   7193 C C   . TRP C 1 353 ? 119.663 122.826 110.272 1.00 30.31  ? 427 TRP C C   1 
ATOM   7194 O O   . TRP C 1 353 ? 118.914 122.327 109.425 1.00 40.47  ? 427 TRP C O   1 
ATOM   7195 C CB  . TRP C 1 353 ? 118.013 124.424 111.321 1.00 30.89  ? 427 TRP C CB  1 
ATOM   7196 C CG  . TRP C 1 353 ? 117.617 123.449 112.382 1.00 29.52  ? 427 TRP C CG  1 
ATOM   7197 C CD1 . TRP C 1 353 ? 118.006 123.457 113.688 1.00 31.03  ? 427 TRP C CD1 1 
ATOM   7198 C CD2 . TRP C 1 353 ? 116.725 122.340 112.235 1.00 23.79  ? 427 TRP C CD2 1 
ATOM   7199 N NE1 . TRP C 1 353 ? 117.423 122.412 114.360 1.00 29.19  ? 427 TRP C NE1 1 
ATOM   7200 C CE2 . TRP C 1 353 ? 116.631 121.711 113.490 1.00 24.72  ? 427 TRP C CE2 1 
ATOM   7201 C CE3 . TRP C 1 353 ? 116.002 121.814 111.161 1.00 30.79  ? 427 TRP C CE3 1 
ATOM   7202 C CZ2 . TRP C 1 353 ? 115.842 120.585 113.701 1.00 32.89  ? 427 TRP C CZ2 1 
ATOM   7203 C CZ3 . TRP C 1 353 ? 115.222 120.694 111.373 1.00 30.28  ? 427 TRP C CZ3 1 
ATOM   7204 C CH2 . TRP C 1 353 ? 115.148 120.092 112.632 1.00 33.11  ? 427 TRP C CH2 1 
ATOM   7205 N N   . ASN C 1 354 ? 120.710 122.182 110.791 1.00 31.20  ? 428 ASN C N   1 
ATOM   7206 C CA  . ASN C 1 354 ? 121.077 120.808 110.443 1.00 30.82  ? 428 ASN C CA  1 
ATOM   7207 C C   . ASN C 1 354 ? 121.354 120.661 108.945 1.00 40.85  ? 428 ASN C C   1 
ATOM   7208 O O   . ASN C 1 354 ? 120.649 119.959 108.217 1.00 45.17  ? 428 ASN C O   1 
ATOM   7209 C CB  . ASN C 1 354 ? 120.002 119.818 110.897 1.00 30.07  ? 428 ASN C CB  1 
ATOM   7210 C CG  . ASN C 1 354 ? 120.541 118.411 111.060 1.00 35.81  ? 428 ASN C CG  1 
ATOM   7211 O OD1 . ASN C 1 354 ? 121.686 118.218 111.468 1.00 39.53  ? 428 ASN C OD1 1 
ATOM   7212 N ND2 . ASN C 1 354 ? 119.719 117.420 110.742 1.00 39.74  ? 428 ASN C ND2 1 
ATOM   7213 N N   . VAL C 1 355 ? 122.400 121.338 108.495 1.00 43.93  ? 429 VAL C N   1 
ATOM   7214 C CA  . VAL C 1 355 ? 122.888 121.188 107.130 1.00 42.06  ? 429 VAL C CA  1 
ATOM   7215 C C   . VAL C 1 355 ? 123.950 120.098 107.105 1.00 49.40  ? 429 VAL C C   1 
ATOM   7216 O O   . VAL C 1 355 ? 124.828 120.042 107.975 1.00 50.84  ? 429 VAL C O   1 
ATOM   7217 C CB  . VAL C 1 355 ? 123.428 122.524 106.584 1.00 44.27  ? 429 VAL C CB  1 
ATOM   7218 C CG1 . VAL C 1 355 ? 122.297 123.525 106.444 1.00 46.08  ? 429 VAL C CG1 1 
ATOM   7219 C CG2 . VAL C 1 355 ? 124.515 123.081 107.492 1.00 46.33  ? 429 VAL C CG2 1 
ATOM   7220 N N   . ARG C 1 356 ? 123.852 119.213 106.114 1.00 55.22  ? 430 ARG C N   1 
ATOM   7221 C CA  . ARG C 1 356 ? 124.751 118.068 105.978 1.00 53.41  ? 430 ARG C CA  1 
ATOM   7222 C C   . ARG C 1 356 ? 124.768 117.210 107.241 1.00 56.10  ? 430 ARG C C   1 
ATOM   7223 O O   . ARG C 1 356 ? 123.729 116.978 107.860 1.00 55.06  ? 430 ARG C O   1 
ATOM   7224 C CB  . ARG C 1 356 ? 126.171 118.530 105.640 1.00 53.22  ? 430 ARG C CB  1 
ATOM   7225 C CG  . ARG C 1 356 ? 127.153 117.393 105.413 1.00 53.99  ? 430 ARG C CG  1 
ATOM   7226 C CD  . ARG C 1 356 ? 128.525 117.918 105.028 1.00 55.12  ? 430 ARG C CD  1 
ATOM   7227 N NE  . ARG C 1 356 ? 129.471 116.840 104.767 1.00 55.10  ? 430 ARG C NE  1 
ATOM   7228 C CZ  . ARG C 1 356 ? 130.242 116.282 105.690 1.00 56.93  ? 430 ARG C CZ  1 
ATOM   7229 N NH1 . ARG C 1 356 ? 130.206 116.677 106.952 1.00 55.62  ? 430 ARG C NH1 1 
ATOM   7230 N NH2 . ARG C 1 356 ? 131.071 115.304 105.338 1.00 55.36  ? 430 ARG C NH2 1 
ATOM   7231 N N   . THR D 1 7   ? 88.152  112.945 133.474 1.00 80.07  ? 73  THR D N   1 
ATOM   7232 C CA  . THR D 1 7   ? 88.153  112.016 134.597 1.00 80.93  ? 73  THR D CA  1 
ATOM   7233 C C   . THR D 1 7   ? 89.496  111.304 134.718 1.00 80.75  ? 73  THR D C   1 
ATOM   7234 O O   . THR D 1 7   ? 90.113  110.946 133.714 1.00 81.19  ? 73  THR D O   1 
ATOM   7235 C CB  . THR D 1 7   ? 87.035  110.965 134.463 1.00 81.96  ? 73  THR D CB  1 
ATOM   7236 O OG1 . THR D 1 7   ? 87.168  110.279 133.212 1.00 82.04  ? 73  THR D OG1 1 
ATOM   7237 C CG2 . THR D 1 7   ? 85.669  111.630 134.529 1.00 78.42  ? 73  THR D CG2 1 
ATOM   7238 N N   . PHE D 1 8   ? 89.945  111.101 135.955 1.00 72.00  ? 74  PHE D N   1 
ATOM   7239 C CA  . PHE D 1 8   ? 91.213  110.431 136.242 1.00 70.98  ? 74  PHE D CA  1 
ATOM   7240 C C   . PHE D 1 8   ? 90.957  109.392 137.328 1.00 71.51  ? 74  PHE D C   1 
ATOM   7241 O O   . PHE D 1 8   ? 90.924  109.723 138.517 1.00 73.78  ? 74  PHE D O   1 
ATOM   7242 C CB  . PHE D 1 8   ? 92.280  111.434 136.667 1.00 69.10  ? 74  PHE D CB  1 
ATOM   7243 C CG  . PHE D 1 8   ? 92.554  112.495 135.643 1.00 71.97  ? 74  PHE D CG  1 
ATOM   7244 C CD1 . PHE D 1 8   ? 93.380  112.238 134.563 1.00 71.26  ? 74  PHE D CD1 1 
ATOM   7245 C CD2 . PHE D 1 8   ? 91.979  113.750 135.756 1.00 71.32  ? 74  PHE D CD2 1 
ATOM   7246 C CE1 . PHE D 1 8   ? 93.632  113.212 133.617 1.00 71.00  ? 74  PHE D CE1 1 
ATOM   7247 C CE2 . PHE D 1 8   ? 92.227  114.728 134.813 1.00 71.24  ? 74  PHE D CE2 1 
ATOM   7248 C CZ  . PHE D 1 8   ? 93.053  114.458 133.742 1.00 71.42  ? 74  PHE D CZ  1 
ATOM   7249 N N   . GLY D 1 9   ? 90.785  108.139 136.921 1.00 73.17  ? 75  GLY D N   1 
ATOM   7250 C CA  . GLY D 1 9   ? 90.476  107.076 137.845 1.00 73.75  ? 75  GLY D CA  1 
ATOM   7251 C C   . GLY D 1 9   ? 88.983  106.886 138.013 1.00 76.22  ? 75  GLY D C   1 
ATOM   7252 O O   . GLY D 1 9   ? 88.171  107.659 137.495 1.00 74.69  ? 75  GLY D O   1 
ATOM   7253 N N   . PRO D 1 10  ? 88.592  105.833 138.737 1.00 77.88  ? 76  PRO D N   1 
ATOM   7254 C CA  . PRO D 1 10  ? 87.157  105.569 138.930 1.00 76.11  ? 76  PRO D CA  1 
ATOM   7255 C C   . PRO D 1 10  ? 86.410  106.692 139.630 1.00 76.33  ? 76  PRO D C   1 
ATOM   7256 O O   . PRO D 1 10  ? 85.227  106.908 139.338 1.00 74.76  ? 76  PRO D O   1 
ATOM   7257 C CB  . PRO D 1 10  ? 87.151  104.283 139.769 1.00 74.53  ? 76  PRO D CB  1 
ATOM   7258 C CG  . PRO D 1 10  ? 88.460  103.632 139.474 1.00 71.89  ? 76  PRO D CG  1 
ATOM   7259 C CD  . PRO D 1 10  ? 89.434  104.753 139.277 1.00 72.84  ? 76  PRO D CD  1 
ATOM   7260 N N   . LYS D 1 11  ? 87.055  107.414 140.541 1.00 77.87  ? 77  LYS D N   1 
ATOM   7261 C CA  . LYS D 1 11  ? 86.372  108.420 141.346 1.00 77.10  ? 77  LYS D CA  1 
ATOM   7262 C C   . LYS D 1 11  ? 86.938  109.821 141.189 1.00 76.58  ? 77  LYS D C   1 
ATOM   7263 O O   . LYS D 1 11  ? 86.169  110.784 141.126 1.00 76.54  ? 77  LYS D O   1 
ATOM   7264 C CB  . LYS D 1 11  ? 86.416  108.022 142.829 1.00 76.04  ? 77  LYS D CB  1 
ATOM   7265 C CG  . LYS D 1 11  ? 85.633  106.761 143.157 1.00 75.49  ? 77  LYS D CG  1 
ATOM   7266 C CD  . LYS D 1 11  ? 85.710  106.433 144.639 1.00 74.74  ? 77  LYS D CD  1 
ATOM   7267 C CE  . LYS D 1 11  ? 84.851  105.226 144.981 1.00 74.85  ? 77  LYS D CE  1 
ATOM   7268 N NZ  . LYS D 1 11  ? 85.376  103.978 144.362 1.00 74.16  ? 77  LYS D NZ  1 
ATOM   7269 N N   . ALA D 1 12  ? 88.258  109.966 141.125 1.00 79.01  ? 78  ALA D N   1 
ATOM   7270 C CA  . ALA D 1 12  ? 88.862  111.289 141.065 1.00 78.76  ? 78  ALA D CA  1 
ATOM   7271 C C   . ALA D 1 12  ? 88.602  111.952 139.716 1.00 81.67  ? 78  ALA D C   1 
ATOM   7272 O O   . ALA D 1 12  ? 88.524  111.292 138.676 1.00 80.95  ? 78  ALA D O   1 
ATOM   7273 C CB  . ALA D 1 12  ? 90.365  111.203 141.324 1.00 78.00  ? 78  ALA D CB  1 
ATOM   7274 N N   . THR D 1 13  ? 88.467  113.275 139.746 1.00 83.54  ? 79  THR D N   1 
ATOM   7275 C CA  . THR D 1 13  ? 88.224  114.054 138.540 1.00 83.91  ? 79  THR D CA  1 
ATOM   7276 C C   . THR D 1 13  ? 88.651  115.492 138.792 1.00 83.52  ? 79  THR D C   1 
ATOM   7277 O O   . THR D 1 13  ? 88.852  115.908 139.936 1.00 82.58  ? 79  THR D O   1 
ATOM   7278 C CB  . THR D 1 13  ? 86.742  113.990 138.125 1.00 83.56  ? 79  THR D CB  1 
ATOM   7279 O OG1 . THR D 1 13  ? 85.922  114.469 139.197 1.00 81.24  ? 79  THR D OG1 1 
ATOM   7280 C CG2 . THR D 1 13  ? 86.296  112.545 137.961 1.00 82.43  ? 79  THR D CG2 1 
ATOM   7281 N N   . VAL D 1 14  ? 88.790  116.244 137.706 1.00 86.65  ? 80  VAL D N   1 
ATOM   7282 C CA  . VAL D 1 14  ? 89.175  117.647 137.794 1.00 86.87  ? 80  VAL D CA  1 
ATOM   7283 C C   . VAL D 1 14  ? 88.011  118.541 137.385 1.00 85.08  ? 80  VAL D C   1 
ATOM   7284 O O   . VAL D 1 14  ? 86.950  118.055 136.993 1.00 86.40  ? 80  VAL D O   1 
ATOM   7285 C CB  . VAL D 1 14  ? 90.415  117.943 136.932 1.00 85.92  ? 80  VAL D CB  1 
ATOM   7286 C CG1 . VAL D 1 14  ? 91.617  117.167 137.447 1.00 84.35  ? 80  VAL D CG1 1 
ATOM   7287 C CG2 . VAL D 1 14  ? 90.138  117.608 135.474 1.00 85.47  ? 80  VAL D CG2 1 
ATOM   7288 N N   . VAL D 1 22  ? 93.817  124.656 138.557 1.00 56.04  ? 96  VAL D N   1 
ATOM   7289 C CA  . VAL D 1 22  ? 93.411  123.268 138.385 1.00 56.51  ? 96  VAL D CA  1 
ATOM   7290 C C   . VAL D 1 22  ? 93.384  122.559 139.733 1.00 57.49  ? 96  VAL D C   1 
ATOM   7291 O O   . VAL D 1 22  ? 94.424  122.162 140.256 1.00 58.20  ? 96  VAL D O   1 
ATOM   7292 C CB  . VAL D 1 22  ? 94.337  122.534 137.402 1.00 56.95  ? 96  VAL D CB  1 
ATOM   7293 C CG1 . VAL D 1 22  ? 93.726  121.206 136.986 1.00 57.55  ? 96  VAL D CG1 1 
ATOM   7294 C CG2 . VAL D 1 22  ? 94.615  123.404 136.185 1.00 55.62  ? 96  VAL D CG2 1 
ATOM   7295 N N   . ARG D 1 23  ? 92.188  122.402 140.289 1.00 66.19  ? 97  ARG D N   1 
ATOM   7296 C CA  . ARG D 1 23  ? 92.001  121.767 141.584 1.00 65.15  ? 97  ARG D CA  1 
ATOM   7297 C C   . ARG D 1 23  ? 91.598  120.306 141.410 1.00 67.10  ? 97  ARG D C   1 
ATOM   7298 O O   . ARG D 1 23  ? 91.317  119.834 140.307 1.00 70.54  ? 97  ARG D O   1 
ATOM   7299 C CB  . ARG D 1 23  ? 90.948  122.517 142.408 1.00 65.27  ? 97  ARG D CB  1 
ATOM   7300 C CG  . ARG D 1 23  ? 91.457  123.787 143.078 1.00 65.88  ? 97  ARG D CG  1 
ATOM   7301 C CD  . ARG D 1 23  ? 91.471  124.965 142.116 1.00 68.93  ? 97  ARG D CD  1 
ATOM   7302 N NE  . ARG D 1 23  ? 90.127  125.337 141.688 1.00 70.33  ? 97  ARG D NE  1 
ATOM   7303 C CZ  . ARG D 1 23  ? 89.863  126.153 140.677 1.00 70.64  ? 97  ARG D CZ  1 
ATOM   7304 N NH1 . ARG D 1 23  ? 90.831  126.702 139.961 1.00 69.56  ? 97  ARG D NH1 1 
ATOM   7305 N NH2 . ARG D 1 23  ? 88.596  126.423 140.375 1.00 68.48  ? 97  ARG D NH2 1 
ATOM   7306 N N   . LEU D 1 24  ? 91.575  119.589 142.530 1.00 63.74  ? 98  LEU D N   1 
ATOM   7307 C CA  . LEU D 1 24  ? 91.248  118.171 142.557 1.00 63.60  ? 98  LEU D CA  1 
ATOM   7308 C C   . LEU D 1 24  ? 89.931  117.963 143.292 1.00 66.11  ? 98  LEU D C   1 
ATOM   7309 O O   . LEU D 1 24  ? 89.764  118.436 144.422 1.00 67.55  ? 98  LEU D O   1 
ATOM   7310 C CB  . LEU D 1 24  ? 92.364  117.370 143.230 1.00 60.37  ? 98  LEU D CB  1 
ATOM   7311 C CG  . LEU D 1 24  ? 92.172  115.855 143.304 1.00 60.90  ? 98  LEU D CG  1 
ATOM   7312 C CD1 . LEU D 1 24  ? 92.419  115.215 141.948 1.00 62.32  ? 98  LEU D CD1 1 
ATOM   7313 C CD2 . LEU D 1 24  ? 93.090  115.258 144.357 1.00 62.00  ? 98  LEU D CD2 1 
ATOM   7314 N N   . THR D 1 25  ? 89.004  117.258 142.650 1.00 71.05  ? 99  THR D N   1 
ATOM   7315 C CA  . THR D 1 25  ? 87.710  116.933 143.230 1.00 69.79  ? 99  THR D CA  1 
ATOM   7316 C C   . THR D 1 25  ? 87.524  115.422 143.246 1.00 70.97  ? 99  THR D C   1 
ATOM   7317 O O   . THR D 1 25  ? 87.983  114.715 142.344 1.00 73.99  ? 99  THR D O   1 
ATOM   7318 C CB  . THR D 1 25  ? 86.561  117.589 142.453 1.00 70.80  ? 99  THR D CB  1 
ATOM   7319 O OG1 . THR D 1 25  ? 86.506  117.049 141.127 1.00 72.52  ? 99  THR D OG1 1 
ATOM   7320 C CG2 . THR D 1 25  ? 86.760  119.096 142.375 1.00 69.38  ? 99  THR D CG2 1 
ATOM   7321 N N   . TRP D 1 26  ? 86.847  114.931 144.282 1.00 62.49  ? 100 TRP D N   1 
ATOM   7322 C CA  . TRP D 1 26  ? 86.676  113.496 144.473 1.00 63.15  ? 100 TRP D CA  1 
ATOM   7323 C C   . TRP D 1 26  ? 85.286  112.991 144.118 1.00 62.78  ? 100 TRP D C   1 
ATOM   7324 O O   . TRP D 1 26  ? 85.155  111.834 143.706 1.00 64.22  ? 100 TRP D O   1 
ATOM   7325 C CB  . TRP D 1 26  ? 86.981  113.112 145.925 1.00 61.77  ? 100 TRP D CB  1 
ATOM   7326 C CG  . TRP D 1 26  ? 88.416  113.283 146.307 1.00 60.29  ? 100 TRP D CG  1 
ATOM   7327 C CD1 . TRP D 1 26  ? 88.934  114.231 147.138 1.00 58.72  ? 100 TRP D CD1 1 
ATOM   7328 C CD2 . TRP D 1 26  ? 89.519  112.481 145.875 1.00 56.42  ? 100 TRP D CD2 1 
ATOM   7329 N NE1 . TRP D 1 26  ? 90.293  114.069 147.250 1.00 60.93  ? 100 TRP D NE1 1 
ATOM   7330 C CE2 . TRP D 1 26  ? 90.677  113.001 146.483 1.00 58.38  ? 100 TRP D CE2 1 
ATOM   7331 C CE3 . TRP D 1 26  ? 89.641  111.373 145.031 1.00 58.57  ? 100 TRP D CE3 1 
ATOM   7332 C CZ2 . TRP D 1 26  ? 91.939  112.452 146.275 1.00 59.37  ? 100 TRP D CZ2 1 
ATOM   7333 C CZ3 . TRP D 1 26  ? 90.894  110.830 144.827 1.00 59.68  ? 100 TRP D CZ3 1 
ATOM   7334 C CH2 . TRP D 1 26  ? 92.027  111.371 145.445 1.00 59.37  ? 100 TRP D CH2 1 
ATOM   7335 N N   . ASN D 1 27  ? 84.251  113.819 144.286 1.00 72.74  ? 101 ASN D N   1 
ATOM   7336 C CA  . ASN D 1 27  ? 82.861  113.413 144.092 1.00 76.30  ? 101 ASN D CA  1 
ATOM   7337 C C   . ASN D 1 27  ? 82.500  112.301 145.071 1.00 74.79  ? 101 ASN D C   1 
ATOM   7338 O O   . ASN D 1 27  ? 81.672  112.498 145.966 1.00 72.36  ? 101 ASN D O   1 
ATOM   7339 C CB  . ASN D 1 27  ? 82.608  112.976 142.644 1.00 75.55  ? 101 ASN D CB  1 
ATOM   7340 C CG  . ASN D 1 27  ? 81.212  112.420 142.435 1.00 74.89  ? 101 ASN D CG  1 
ATOM   7341 O OD1 . ASN D 1 27  ? 80.941  111.257 142.735 1.00 74.70  ? 101 ASN D OD1 1 
ATOM   7342 N ND2 . ASN D 1 27  ? 80.316  113.253 141.918 1.00 73.07  ? 101 ASN D ND2 1 
ATOM   7343 N N   . LYS D 1 28  ? 83.115  111.134 144.909 1.00 73.61  ? 102 LYS D N   1 
ATOM   7344 C CA  . LYS D 1 28  ? 82.997  110.041 145.862 1.00 72.27  ? 102 LYS D CA  1 
ATOM   7345 C C   . LYS D 1 28  ? 84.249  109.991 146.727 1.00 70.49  ? 102 LYS D C   1 
ATOM   7346 O O   . LYS D 1 28  ? 85.359  110.236 146.244 1.00 70.38  ? 102 LYS D O   1 
ATOM   7347 C CB  . LYS D 1 28  ? 82.786  108.708 145.143 1.00 72.20  ? 102 LYS D CB  1 
ATOM   7348 C CG  . LYS D 1 28  ? 81.446  108.588 144.435 1.00 72.82  ? 102 LYS D CG  1 
ATOM   7349 C CD  . LYS D 1 28  ? 81.313  107.253 143.723 1.00 73.35  ? 102 LYS D CD  1 
ATOM   7350 C CE  . LYS D 1 28  ? 79.964  107.124 143.035 1.00 74.44  ? 102 LYS D CE  1 
ATOM   7351 N NZ  . LYS D 1 28  ? 79.830  105.829 142.313 1.00 72.59  ? 102 LYS D NZ  1 
ATOM   7352 N N   . SER D 1 29  ? 84.064  109.683 148.005 1.00 64.21  ? 103 SER D N   1 
ATOM   7353 C CA  . SER D 1 29  ? 85.181  109.680 148.939 1.00 66.38  ? 103 SER D CA  1 
ATOM   7354 C C   . SER D 1 29  ? 86.186  108.599 148.553 1.00 66.30  ? 103 SER D C   1 
ATOM   7355 O O   . SER D 1 29  ? 85.790  107.449 148.312 1.00 68.54  ? 103 SER D O   1 
ATOM   7356 C CB  . SER D 1 29  ? 84.684  109.453 150.366 1.00 64.48  ? 103 SER D CB  1 
ATOM   7357 O OG  . SER D 1 29  ? 83.857  110.521 150.795 1.00 65.95  ? 103 SER D OG  1 
ATOM   7358 N N   . PRO D 1 30  ? 87.477  108.920 148.472 1.00 50.35  ? 104 PRO D N   1 
ATOM   7359 C CA  . PRO D 1 30  ? 88.465  107.901 148.103 1.00 45.79  ? 104 PRO D CA  1 
ATOM   7360 C C   . PRO D 1 30  ? 88.557  106.805 149.154 1.00 46.26  ? 104 PRO D C   1 
ATOM   7361 O O   . PRO D 1 30  ? 88.550  107.067 150.358 1.00 49.95  ? 104 PRO D O   1 
ATOM   7362 C CB  . PRO D 1 30  ? 89.772  108.696 148.003 1.00 47.54  ? 104 PRO D CB  1 
ATOM   7363 C CG  . PRO D 1 30  ? 89.547  109.900 148.855 1.00 48.95  ? 104 PRO D CG  1 
ATOM   7364 C CD  . PRO D 1 30  ? 88.095  110.235 148.701 1.00 50.86  ? 104 PRO D CD  1 
ATOM   7365 N N   . LYS D 1 31  ? 88.647  105.563 148.681 1.00 48.97  ? 105 LYS D N   1 
ATOM   7366 C CA  . LYS D 1 31  ? 88.780  104.404 149.554 1.00 49.92  ? 105 LYS D CA  1 
ATOM   7367 C C   . LYS D 1 31  ? 89.847  103.418 149.112 1.00 51.45  ? 105 LYS D C   1 
ATOM   7368 O O   . LYS D 1 31  ? 90.193  102.527 149.895 1.00 57.67  ? 105 LYS D O   1 
ATOM   7369 C CB  . LYS D 1 31  ? 87.436  103.681 149.661 1.00 55.31  ? 105 LYS D CB  1 
ATOM   7370 C CG  . LYS D 1 31  ? 86.349  104.489 150.353 1.00 53.95  ? 105 LYS D CG  1 
ATOM   7371 C CD  . LYS D 1 31  ? 85.038  103.723 150.403 1.00 54.36  ? 105 LYS D CD  1 
ATOM   7372 C CE  . LYS D 1 31  ? 83.959  104.521 151.116 1.00 55.95  ? 105 LYS D CE  1 
ATOM   7373 N NZ  . LYS D 1 31  ? 82.661  103.792 151.151 1.00 56.10  ? 105 LYS D NZ  1 
ATOM   7374 N N   . SER D 1 32  ? 90.369  103.534 147.895 1.00 37.44  ? 106 SER D N   1 
ATOM   7375 C CA  . SER D 1 32  ? 91.411  102.654 147.388 1.00 31.81  ? 106 SER D CA  1 
ATOM   7376 C C   . SER D 1 32  ? 92.648  103.481 147.075 1.00 37.61  ? 106 SER D C   1 
ATOM   7377 O O   . SER D 1 32  ? 92.575  104.449 146.313 1.00 47.36  ? 106 SER D O   1 
ATOM   7378 C CB  . SER D 1 32  ? 90.936  101.912 146.138 1.00 41.36  ? 106 SER D CB  1 
ATOM   7379 O OG  . SER D 1 32  ? 91.860  100.912 145.756 1.00 47.89  ? 106 SER D OG  1 
ATOM   7380 N N   . VAL D 1 33  ? 93.779  103.101 147.661 1.00 23.21  ? 107 VAL D N   1 
ATOM   7381 C CA  . VAL D 1 33  ? 95.039  103.802 147.457 1.00 17.65  ? 107 VAL D CA  1 
ATOM   7382 C C   . VAL D 1 33  ? 96.122  102.781 147.141 1.00 26.53  ? 107 VAL D C   1 
ATOM   7383 O O   . VAL D 1 33  ? 96.152  101.690 147.721 1.00 39.30  ? 107 VAL D O   1 
ATOM   7384 C CB  . VAL D 1 33  ? 95.419  104.662 148.683 1.00 23.78  ? 107 VAL D CB  1 
ATOM   7385 C CG1 . VAL D 1 33  ? 95.624  103.797 149.907 1.00 34.58  ? 107 VAL D CG1 1 
ATOM   7386 C CG2 . VAL D 1 33  ? 96.662  105.488 148.398 1.00 34.55  ? 107 VAL D CG2 1 
ATOM   7387 N N   . LEU D 1 34  ? 96.993  103.124 146.198 1.00 30.80  ? 108 LEU D N   1 
ATOM   7388 C CA  . LEU D 1 34  ? 98.122  102.286 145.819 1.00 26.63  ? 108 LEU D CA  1 
ATOM   7389 C C   . LEU D 1 34  ? 99.406  102.968 146.266 1.00 31.53  ? 108 LEU D C   1 
ATOM   7390 O O   . LEU D 1 34  ? 99.668  104.115 145.887 1.00 42.88  ? 108 LEU D O   1 
ATOM   7391 C CB  . LEU D 1 34  ? 98.138  102.038 144.311 1.00 31.04  ? 108 LEU D CB  1 
ATOM   7392 C CG  . LEU D 1 34  ? 99.426  101.449 143.732 1.00 33.41  ? 108 LEU D CG  1 
ATOM   7393 C CD1 . LEU D 1 34  ? 99.677  100.062 144.290 1.00 37.35  ? 108 LEU D CD1 1 
ATOM   7394 C CD2 . LEU D 1 34  ? 99.372  101.415 142.215 1.00 36.99  ? 108 LEU D CD2 1 
ATOM   7395 N N   . VAL D 1 35  ? 100.199 102.267 147.070 1.00 25.33  ? 109 VAL D N   1 
ATOM   7396 C CA  . VAL D 1 35  ? 101.498 102.747 147.521 1.00 19.92  ? 109 VAL D CA  1 
ATOM   7397 C C   . VAL D 1 35  ? 102.573 101.970 146.776 1.00 26.21  ? 109 VAL D C   1 
ATOM   7398 O O   . VAL D 1 35  ? 102.557 100.733 146.758 1.00 37.80  ? 109 VAL D O   1 
ATOM   7399 C CB  . VAL D 1 35  ? 101.657 102.615 149.046 1.00 16.96  ? 109 VAL D CB  1 
ATOM   7400 C CG1 . VAL D 1 35  ? 100.808 103.658 149.751 1.00 29.22  ? 109 VAL D CG1 1 
ATOM   7401 C CG2 . VAL D 1 35  ? 101.258 101.226 149.511 1.00 35.17  ? 109 VAL D CG2 1 
ATOM   7402 N N   . ILE D 1 36  ? 103.492 102.693 146.143 1.00 35.28  ? 110 ILE D N   1 
ATOM   7403 C CA  . ILE D 1 36  ? 104.545 102.095 145.331 1.00 33.25  ? 110 ILE D CA  1 
ATOM   7404 C C   . ILE D 1 36  ? 105.877 102.388 146.003 1.00 38.31  ? 110 ILE D C   1 
ATOM   7405 O O   . ILE D 1 36  ? 106.218 103.553 146.240 1.00 41.90  ? 110 ILE D O   1 
ATOM   7406 C CB  . ILE D 1 36  ? 104.528 102.623 143.889 1.00 35.29  ? 110 ILE D CB  1 
ATOM   7407 C CG1 . ILE D 1 36  ? 103.217 102.244 143.200 1.00 34.85  ? 110 ILE D CG1 1 
ATOM   7408 C CG2 . ILE D 1 36  ? 105.697 102.055 143.108 1.00 40.09  ? 110 ILE D CG2 1 
ATOM   7409 C CD1 . ILE D 1 36  ? 103.004 102.937 141.873 1.00 38.96  ? 110 ILE D CD1 1 
ATOM   7410 N N   . LYS D 1 37  ? 106.624 101.333 146.308 1.00 43.23  ? 111 LYS D N   1 
ATOM   7411 C CA  . LYS D 1 37  ? 107.917 101.441 146.960 1.00 43.44  ? 111 LYS D CA  1 
ATOM   7412 C C   . LYS D 1 37  ? 109.026 101.369 145.910 1.00 48.79  ? 111 LYS D C   1 
ATOM   7413 O O   . LYS D 1 37  ? 108.809 100.945 144.773 1.00 49.49  ? 111 LYS D O   1 
ATOM   7414 C CB  . LYS D 1 37  ? 108.063 100.331 148.008 1.00 47.89  ? 111 LYS D CB  1 
ATOM   7415 C CG  . LYS D 1 37  ? 109.331 100.360 148.846 1.00 48.70  ? 111 LYS D CG  1 
ATOM   7416 C CD  . LYS D 1 37  ? 109.325 99.246  149.877 1.00 45.88  ? 111 LYS D CD  1 
ATOM   7417 C CE  . LYS D 1 37  ? 110.544 99.323  150.778 1.00 48.26  ? 111 LYS D CE  1 
ATOM   7418 N NZ  . LYS D 1 37  ? 111.798 99.029  150.032 1.00 51.71  ? 111 LYS D NZ  1 
ATOM   7419 N N   . LYS D 1 38  ? 110.227 101.795 146.304 1.00 54.63  ? 112 LYS D N   1 
ATOM   7420 C CA  . LYS D 1 38  ? 111.366 101.895 145.400 1.00 54.78  ? 112 LYS D CA  1 
ATOM   7421 C C   . LYS D 1 38  ? 112.095 100.545 145.230 1.00 60.77  ? 112 LYS D C   1 
ATOM   7422 O O   . LYS D 1 38  ? 113.272 100.506 144.849 1.00 61.52  ? 112 LYS D O   1 
ATOM   7423 C CB  . LYS D 1 38  ? 112.311 102.996 145.905 1.00 53.69  ? 112 LYS D CB  1 
ATOM   7424 C CG  . LYS D 1 38  ? 113.508 103.348 145.023 1.00 55.80  ? 112 LYS D CG  1 
ATOM   7425 C CD  . LYS D 1 38  ? 114.078 104.709 145.383 1.00 58.27  ? 112 LYS D CD  1 
ATOM   7426 C CE  . LYS D 1 38  ? 115.590 104.730 145.234 1.00 60.92  ? 112 LYS D CE  1 
ATOM   7427 N NZ  . LYS D 1 38  ? 116.008 104.606 143.811 1.00 59.15  ? 112 LYS D NZ  1 
ATOM   7428 N N   . MET D 1 39  ? 111.406 99.441  145.508 1.00 65.99  ? 113 MET D N   1 
ATOM   7429 C CA  . MET D 1 39  ? 111.931 98.076  145.336 1.00 63.82  ? 113 MET D CA  1 
ATOM   7430 C C   . MET D 1 39  ? 113.093 97.904  146.313 1.00 66.07  ? 113 MET D C   1 
ATOM   7431 O O   . MET D 1 39  ? 112.910 98.144  147.518 1.00 66.86  ? 113 MET D O   1 
ATOM   7432 C CB  . MET D 1 39  ? 112.260 97.823  143.867 1.00 63.92  ? 113 MET D CB  1 
ATOM   7433 C CG  . MET D 1 39  ? 111.052 97.539  142.989 1.00 66.80  ? 113 MET D CG  1 
ATOM   7434 S SD  . MET D 1 39  ? 110.058 99.004  142.650 1.00 71.10  ? 113 MET D SD  1 
ATOM   7435 C CE  . MET D 1 39  ? 111.104 99.861  141.475 1.00 63.77  ? 113 MET D CE  1 
ATOM   7436 N N   . ARG D 1 40  ? 114.277 97.497  145.861 1.00 73.56  ? 114 ARG D N   1 
ATOM   7437 C CA  . ARG D 1 40  ? 115.390 97.213  146.761 1.00 73.87  ? 114 ARG D CA  1 
ATOM   7438 C C   . ARG D 1 40  ? 115.894 98.508  147.385 1.00 70.90  ? 114 ARG D C   1 
ATOM   7439 O O   . ARG D 1 40  ? 116.574 99.303  146.729 1.00 72.57  ? 114 ARG D O   1 
ATOM   7440 C CB  . ARG D 1 40  ? 116.523 96.501  146.019 1.00 75.90  ? 114 ARG D CB  1 
ATOM   7441 C CG  . ARG D 1 40  ? 116.175 95.094  145.560 1.00 75.21  ? 114 ARG D CG  1 
ATOM   7442 C CD  . ARG D 1 40  ? 117.316 94.368  144.865 1.00 73.93  ? 114 ARG D CD  1 
ATOM   7443 N NE  . ARG D 1 40  ? 116.913 93.050  144.383 1.00 75.92  ? 114 ARG D NE  1 
ATOM   7444 C CZ  . ARG D 1 40  ? 117.680 92.261  143.644 1.00 76.21  ? 114 ARG D CZ  1 
ATOM   7445 N NH1 . ARG D 1 40  ? 118.901 92.651  143.300 1.00 75.08  ? 114 ARG D NH1 1 
ATOM   7446 N NH2 . ARG D 1 40  ? 117.231 91.077  143.249 1.00 74.96  ? 114 ARG D NH2 1 
ATOM   7447 N N   . ASP D 1 41  ? 115.560 98.718  148.655 1.00 61.90  ? 115 ASP D N   1 
ATOM   7448 C CA  . ASP D 1 41  ? 116.015 99.885  149.397 1.00 62.51  ? 115 ASP D CA  1 
ATOM   7449 C C   . ASP D 1 41  ? 115.969 99.539  150.879 1.00 64.92  ? 115 ASP D C   1 
ATOM   7450 O O   . ASP D 1 41  ? 115.352 98.553  151.286 1.00 66.23  ? 115 ASP D O   1 
ATOM   7451 C CB  . ASP D 1 41  ? 115.161 101.118 149.080 1.00 64.79  ? 115 ASP D CB  1 
ATOM   7452 C CG  . ASP D 1 41  ? 115.811 102.412 149.533 1.00 68.04  ? 115 ASP D CG  1 
ATOM   7453 O OD1 . ASP D 1 41  ? 116.045 102.571 150.750 1.00 67.80  ? 115 ASP D OD1 1 
ATOM   7454 O OD2 . ASP D 1 41  ? 116.087 103.272 148.671 1.00 67.87  ? 115 ASP D OD2 1 
ATOM   7455 N N   . ALA D 1 42  ? 116.640 100.358 151.680 1.00 57.07  ? 116 ALA D N   1 
ATOM   7456 C CA  . ALA D 1 42  ? 116.726 100.132 153.118 1.00 57.42  ? 116 ALA D CA  1 
ATOM   7457 C C   . ALA D 1 42  ? 116.084 101.233 153.943 1.00 56.13  ? 116 ALA D C   1 
ATOM   7458 O O   . ALA D 1 42  ? 115.472 100.946 154.974 1.00 60.50  ? 116 ALA D O   1 
ATOM   7459 C CB  . ALA D 1 42  ? 118.194 99.971  153.540 1.00 59.66  ? 116 ALA D CB  1 
ATOM   7460 N N   . SER D 1 43  ? 116.203 102.489 153.517 1.00 53.58  ? 117 SER D N   1 
ATOM   7461 C CA  . SER D 1 43  ? 115.649 103.610 154.264 1.00 53.88  ? 117 SER D CA  1 
ATOM   7462 C C   . SER D 1 43  ? 114.151 103.780 154.058 1.00 53.44  ? 117 SER D C   1 
ATOM   7463 O O   . SER D 1 43  ? 113.547 104.638 154.711 1.00 56.55  ? 117 SER D O   1 
ATOM   7464 C CB  . SER D 1 43  ? 116.370 104.904 153.880 1.00 52.87  ? 117 SER D CB  1 
ATOM   7465 O OG  . SER D 1 43  ? 115.810 106.018 154.552 1.00 55.14  ? 117 SER D OG  1 
ATOM   7466 N N   . LEU D 1 44  ? 113.540 102.994 153.173 1.00 49.23  ? 118 LEU D N   1 
ATOM   7467 C CA  . LEU D 1 44  ? 112.125 103.120 152.856 1.00 47.25  ? 118 LEU D CA  1 
ATOM   7468 C C   . LEU D 1 44  ? 111.279 102.020 153.486 1.00 51.96  ? 118 LEU D C   1 
ATOM   7469 O O   . LEU D 1 44  ? 110.153 101.786 153.038 1.00 52.64  ? 118 LEU D O   1 
ATOM   7470 C CB  . LEU D 1 44  ? 111.918 103.132 151.342 1.00 48.37  ? 118 LEU D CB  1 
ATOM   7471 C CG  . LEU D 1 44  ? 111.880 104.493 150.646 1.00 43.28  ? 118 LEU D CG  1 
ATOM   7472 C CD1 . LEU D 1 44  ? 113.207 105.224 150.779 1.00 47.02  ? 118 LEU D CD1 1 
ATOM   7473 C CD2 . LEU D 1 44  ? 111.506 104.314 149.190 1.00 47.21  ? 118 LEU D CD2 1 
ATOM   7474 N N   . LEU D 1 45  ? 111.797 101.331 154.502 1.00 51.65  ? 119 LEU D N   1 
ATOM   7475 C CA  . LEU D 1 45  ? 111.011 100.303 155.178 1.00 44.40  ? 119 LEU D CA  1 
ATOM   7476 C C   . LEU D 1 45  ? 110.181 100.881 156.318 1.00 46.27  ? 119 LEU D C   1 
ATOM   7477 O O   . LEU D 1 45  ? 108.970 100.654 156.383 1.00 49.65  ? 119 LEU D O   1 
ATOM   7478 C CB  . LEU D 1 45  ? 111.921 99.186  155.700 1.00 43.73  ? 119 LEU D CB  1 
ATOM   7479 C CG  . LEU D 1 45  ? 112.343 98.079  154.728 1.00 53.25  ? 119 LEU D CG  1 
ATOM   7480 C CD1 . LEU D 1 45  ? 111.127 97.288  154.266 1.00 51.56  ? 119 LEU D CD1 1 
ATOM   7481 C CD2 . LEU D 1 45  ? 113.119 98.619  153.538 1.00 52.34  ? 119 LEU D CD2 1 
ATOM   7482 N N   . GLN D 1 46  ? 110.818 101.621 157.225 1.00 48.16  ? 120 GLN D N   1 
ATOM   7483 C CA  . GLN D 1 46  ? 110.077 102.253 158.314 1.00 48.89  ? 120 GLN D CA  1 
ATOM   7484 C C   . GLN D 1 46  ? 109.037 103.249 157.817 1.00 49.56  ? 120 GLN D C   1 
ATOM   7485 O O   . GLN D 1 46  ? 107.886 103.188 158.285 1.00 53.32  ? 120 GLN D O   1 
ATOM   7486 C CB  . GLN D 1 46  ? 111.057 102.904 159.296 1.00 48.95  ? 120 GLN D CB  1 
ATOM   7487 C CG  . GLN D 1 46  ? 110.442 103.993 160.158 1.00 52.11  ? 120 GLN D CG  1 
ATOM   7488 C CD  . GLN D 1 46  ? 109.516 103.440 161.223 1.00 54.61  ? 120 GLN D CD  1 
ATOM   7489 O OE1 . GLN D 1 46  ? 109.756 102.365 161.773 1.00 55.46  ? 120 GLN D OE1 1 
ATOM   7490 N NE2 . GLN D 1 46  ? 108.449 104.173 161.518 1.00 52.32  ? 120 GLN D NE2 1 
ATOM   7491 N N   . PRO D 1 47  ? 109.349 104.185 156.909 1.00 45.78  ? 121 PRO D N   1 
ATOM   7492 C CA  . PRO D 1 47  ? 108.282 105.064 156.400 1.00 46.21  ? 121 PRO D CA  1 
ATOM   7493 C C   . PRO D 1 47  ? 107.177 104.320 155.672 1.00 42.00  ? 121 PRO D C   1 
ATOM   7494 O O   . PRO D 1 47  ? 106.007 104.699 155.795 1.00 48.46  ? 121 PRO D O   1 
ATOM   7495 C CB  . PRO D 1 47  ? 109.040 106.021 155.471 1.00 43.59  ? 121 PRO D CB  1 
ATOM   7496 C CG  . PRO D 1 47  ? 110.258 105.276 155.084 1.00 45.15  ? 121 PRO D CG  1 
ATOM   7497 C CD  . PRO D 1 47  ? 110.652 104.547 156.324 1.00 46.55  ? 121 PRO D CD  1 
ATOM   7498 N N   . PHE D 1 48  ? 107.510 103.271 154.916 1.00 32.21  ? 122 PHE D N   1 
ATOM   7499 C CA  . PHE D 1 48  ? 106.478 102.486 154.244 1.00 32.80  ? 122 PHE D CA  1 
ATOM   7500 C C   . PHE D 1 48  ? 105.550 101.832 155.256 1.00 44.26  ? 122 PHE D C   1 
ATOM   7501 O O   . PHE D 1 48  ? 104.322 101.865 155.106 1.00 52.70  ? 122 PHE D O   1 
ATOM   7502 C CB  . PHE D 1 48  ? 107.124 101.430 153.348 1.00 40.30  ? 122 PHE D CB  1 
ATOM   7503 C CG  . PHE D 1 48  ? 106.141 100.517 152.670 1.00 36.70  ? 122 PHE D CG  1 
ATOM   7504 C CD1 . PHE D 1 48  ? 105.388 100.960 151.598 1.00 41.36  ? 122 PHE D CD1 1 
ATOM   7505 C CD2 . PHE D 1 48  ? 105.976 99.213  153.104 1.00 38.42  ? 122 PHE D CD2 1 
ATOM   7506 C CE1 . PHE D 1 48  ? 104.489 100.120 150.973 1.00 40.28  ? 122 PHE D CE1 1 
ATOM   7507 C CE2 . PHE D 1 48  ? 105.077 98.371  152.484 1.00 33.94  ? 122 PHE D CE2 1 
ATOM   7508 C CZ  . PHE D 1 48  ? 104.333 98.824  151.417 1.00 40.07  ? 122 PHE D CZ  1 
ATOM   7509 N N   . LYS D 1 49  ? 106.125 101.232 156.301 1.00 49.33  ? 123 LYS D N   1 
ATOM   7510 C CA  . LYS D 1 49  ? 105.312 100.601 157.334 1.00 47.65  ? 123 LYS D CA  1 
ATOM   7511 C C   . LYS D 1 49  ? 104.438 101.623 158.045 1.00 45.14  ? 123 LYS D C   1 
ATOM   7512 O O   . LYS D 1 49  ? 103.252 101.374 158.285 1.00 54.57  ? 123 LYS D O   1 
ATOM   7513 C CB  . LYS D 1 49  ? 106.210 99.876  158.336 1.00 51.01  ? 123 LYS D CB  1 
ATOM   7514 C CG  . LYS D 1 49  ? 106.720 98.530  157.856 1.00 53.39  ? 123 LYS D CG  1 
ATOM   7515 C CD  . LYS D 1 49  ? 107.711 97.937  158.843 1.00 55.00  ? 123 LYS D CD  1 
ATOM   7516 C CE  . LYS D 1 49  ? 108.833 97.207  158.126 1.00 55.95  ? 123 LYS D CE  1 
ATOM   7517 N NZ  . LYS D 1 49  ? 110.086 97.188  158.930 1.00 54.48  ? 123 LYS D NZ  1 
ATOM   7518 N N   . GLU D 1 50  ? 105.004 102.785 158.381 1.00 36.75  ? 124 GLU D N   1 
ATOM   7519 C CA  . GLU D 1 50  ? 104.228 103.818 159.059 1.00 36.91  ? 124 GLU D CA  1 
ATOM   7520 C C   . GLU D 1 50  ? 103.081 104.310 158.186 1.00 45.30  ? 124 GLU D C   1 
ATOM   7521 O O   . GLU D 1 50  ? 101.948 104.463 158.661 1.00 50.44  ? 124 GLU D O   1 
ATOM   7522 C CB  . GLU D 1 50  ? 105.136 104.982 159.452 1.00 42.65  ? 124 GLU D CB  1 
ATOM   7523 C CG  . GLU D 1 50  ? 104.555 105.891 160.519 1.00 48.65  ? 124 GLU D CG  1 
ATOM   7524 C CD  . GLU D 1 50  ? 105.559 106.908 161.028 1.00 52.62  ? 124 GLU D CD  1 
ATOM   7525 O OE1 . GLU D 1 50  ? 106.769 106.602 161.030 1.00 51.06  ? 124 GLU D OE1 1 
ATOM   7526 O OE2 . GLU D 1 50  ? 105.137 108.015 161.424 1.00 53.81  ? 124 GLU D OE2 1 
ATOM   7527 N N   . LEU D 1 51  ? 103.355 104.559 156.903 1.00 46.49  ? 125 LEU D N   1 
ATOM   7528 C CA  . LEU D 1 51  ? 102.320 105.051 156.003 1.00 38.82  ? 125 LEU D CA  1 
ATOM   7529 C C   . LEU D 1 51  ? 101.221 104.016 155.805 1.00 36.06  ? 125 LEU D C   1 
ATOM   7530 O O   . LEU D 1 51  ? 100.035 104.359 155.811 1.00 44.11  ? 125 LEU D O   1 
ATOM   7531 C CB  . LEU D 1 51  ? 102.938 105.448 154.663 1.00 42.39  ? 125 LEU D CB  1 
ATOM   7532 C CG  . LEU D 1 51  ? 101.960 105.729 153.521 1.00 41.53  ? 125 LEU D CG  1 
ATOM   7533 C CD1 . LEU D 1 51  ? 101.223 107.035 153.761 1.00 39.39  ? 125 LEU D CD1 1 
ATOM   7534 C CD2 . LEU D 1 51  ? 102.688 105.758 152.189 1.00 42.38  ? 125 LEU D CD2 1 
ATOM   7535 N N   . CYS D 1 52  ? 101.590 102.744 155.633 1.00 38.88  ? 126 CYS D N   1 
ATOM   7536 C CA  . CYS D 1 52  ? 100.576 101.709 155.461 1.00 40.38  ? 126 CYS D CA  1 
ATOM   7537 C C   . CYS D 1 52  ? 99.752  101.521 156.728 1.00 46.92  ? 126 CYS D C   1 
ATOM   7538 O O   . CYS D 1 52  ? 98.535  101.318 156.657 1.00 53.27  ? 126 CYS D O   1 
ATOM   7539 C CB  . CYS D 1 52  ? 101.230 100.394 155.042 1.00 44.04  ? 126 CYS D CB  1 
ATOM   7540 S SG  . CYS D 1 52  ? 101.998 100.442 153.410 1.00 56.97  ? 126 CYS D SG  1 
ATOM   7541 N N   . THR D 1 53  ? 100.395 101.584 157.897 1.00 42.47  ? 127 THR D N   1 
ATOM   7542 C CA  . THR D 1 53  ? 99.660  101.460 159.150 1.00 37.77  ? 127 THR D CA  1 
ATOM   7543 C C   . THR D 1 53  ? 98.685  102.615 159.332 1.00 40.20  ? 127 THR D C   1 
ATOM   7544 O O   . THR D 1 53  ? 97.545  102.413 159.767 1.00 49.96  ? 127 THR D O   1 
ATOM   7545 C CB  . THR D 1 53  ? 100.635 101.388 160.325 1.00 44.00  ? 127 THR D CB  1 
ATOM   7546 O OG1 . THR D 1 53  ? 101.560 100.313 160.114 1.00 50.06  ? 127 THR D OG1 1 
ATOM   7547 C CG2 . THR D 1 53  ? 99.887  101.153 161.627 1.00 47.37  ? 127 THR D CG2 1 
ATOM   7548 N N   . HIS D 1 54  ? 99.113  103.837 159.002 1.00 42.04  ? 128 HIS D N   1 
ATOM   7549 C CA  . HIS D 1 54  ? 98.225  104.987 159.141 1.00 38.33  ? 128 HIS D CA  1 
ATOM   7550 C C   . HIS D 1 54  ? 97.081  104.938 158.136 1.00 38.73  ? 128 HIS D C   1 
ATOM   7551 O O   . HIS D 1 54  ? 95.938  105.254 158.480 1.00 43.76  ? 128 HIS D O   1 
ATOM   7552 C CB  . HIS D 1 54  ? 99.010  106.288 158.989 1.00 34.69  ? 128 HIS D CB  1 
ATOM   7553 C CG  . HIS D 1 54  ? 98.143  107.491 158.784 1.00 37.14  ? 128 HIS D CG  1 
ATOM   7554 N ND1 . HIS D 1 54  ? 97.708  107.892 157.539 1.00 46.97  ? 128 HIS D ND1 1 
ATOM   7555 C CD2 . HIS D 1 54  ? 97.614  108.370 159.668 1.00 40.69  ? 128 HIS D CD2 1 
ATOM   7556 C CE1 . HIS D 1 54  ? 96.957  108.972 157.664 1.00 41.54  ? 128 HIS D CE1 1 
ATOM   7557 N NE2 . HIS D 1 54  ? 96.885  109.283 158.945 1.00 37.16  ? 128 HIS D NE2 1 
ATOM   7558 N N   . LEU D 1 55  ? 97.363  104.550 156.890 1.00 44.76  ? 129 LEU D N   1 
ATOM   7559 C CA  . LEU D 1 55  ? 96.337  104.580 155.853 1.00 38.59  ? 129 LEU D CA  1 
ATOM   7560 C C   . LEU D 1 55  ? 95.197  103.609 156.134 1.00 40.31  ? 129 LEU D C   1 
ATOM   7561 O O   . LEU D 1 55  ? 94.105  103.779 155.582 1.00 49.58  ? 129 LEU D O   1 
ATOM   7562 C CB  . LEU D 1 55  ? 96.952  104.276 154.485 1.00 38.87  ? 129 LEU D CB  1 
ATOM   7563 C CG  . LEU D 1 55  ? 97.812  105.368 153.840 1.00 40.66  ? 129 LEU D CG  1 
ATOM   7564 C CD1 . LEU D 1 55  ? 98.291  104.929 152.464 1.00 43.62  ? 129 LEU D CD1 1 
ATOM   7565 C CD2 . LEU D 1 55  ? 97.085  106.698 153.770 1.00 44.47  ? 129 LEU D CD2 1 
ATOM   7566 N N   . MET D 1 56  ? 95.423  102.600 156.973 1.00 43.12  ? 130 MET D N   1 
ATOM   7567 C CA  . MET D 1 56  ? 94.385  101.656 157.361 1.00 44.63  ? 130 MET D CA  1 
ATOM   7568 C C   . MET D 1 56  ? 93.810  101.936 158.745 1.00 44.88  ? 130 MET D C   1 
ATOM   7569 O O   . MET D 1 56  ? 93.065  101.104 159.272 1.00 52.95  ? 130 MET D O   1 
ATOM   7570 C CB  . MET D 1 56  ? 94.920  100.224 157.284 1.00 41.06  ? 130 MET D CB  1 
ATOM   7571 C CG  . MET D 1 56  ? 95.234  99.773  155.867 1.00 44.89  ? 130 MET D CG  1 
ATOM   7572 S SD  . MET D 1 56  ? 95.808  98.070  155.751 1.00 54.43  ? 130 MET D SD  1 
ATOM   7573 C CE  . MET D 1 56  ? 97.471  98.235  156.389 1.00 50.22  ? 130 MET D CE  1 
ATOM   7574 N N   . GLU D 1 57  ? 94.130  103.083 159.346 1.00 45.19  ? 131 GLU D N   1 
ATOM   7575 C CA  . GLU D 1 57  ? 93.475  103.486 160.583 1.00 45.93  ? 131 GLU D CA  1 
ATOM   7576 C C   . GLU D 1 57  ? 92.180  104.248 160.335 1.00 51.06  ? 131 GLU D C   1 
ATOM   7577 O O   . GLU D 1 57  ? 91.395  104.427 161.273 1.00 59.33  ? 131 GLU D O   1 
ATOM   7578 C CB  . GLU D 1 57  ? 94.413  104.339 161.447 1.00 47.72  ? 131 GLU D CB  1 
ATOM   7579 C CG  . GLU D 1 57  ? 94.400  105.823 161.122 1.00 53.86  ? 131 GLU D CG  1 
ATOM   7580 C CD  . GLU D 1 57  ? 95.366  106.617 161.980 1.00 56.62  ? 131 GLU D CD  1 
ATOM   7581 O OE1 . GLU D 1 57  ? 96.458  106.094 162.289 1.00 56.40  ? 131 GLU D OE1 1 
ATOM   7582 O OE2 . GLU D 1 57  ? 95.032  107.763 162.349 1.00 54.73  ? 131 GLU D OE2 1 
ATOM   7583 N N   . GLU D 1 58  ? 91.939  104.699 159.101 1.00 44.72  ? 132 GLU D N   1 
ATOM   7584 C CA  . GLU D 1 58  ? 90.655  105.268 158.707 1.00 50.93  ? 132 GLU D CA  1 
ATOM   7585 C C   . GLU D 1 58  ? 89.901  104.367 157.734 1.00 52.20  ? 132 GLU D C   1 
ATOM   7586 O O   . GLU D 1 58  ? 89.060  104.851 156.969 1.00 51.62  ? 132 GLU D O   1 
ATOM   7587 C CB  . GLU D 1 58  ? 90.840  106.667 158.111 1.00 48.12  ? 132 GLU D CB  1 
ATOM   7588 C CG  . GLU D 1 58  ? 91.540  106.711 156.761 1.00 52.84  ? 132 GLU D CG  1 
ATOM   7589 C CD  . GLU D 1 58  ? 93.047  106.719 156.894 1.00 55.36  ? 132 GLU D CD  1 
ATOM   7590 O OE1 . GLU D 1 58  ? 93.544  106.395 157.991 1.00 54.26  ? 132 GLU D OE1 1 
ATOM   7591 O OE2 . GLU D 1 58  ? 93.736  107.041 155.903 1.00 57.47  ? 132 GLU D OE2 1 
ATOM   7592 N N   . ASN D 1 59  ? 90.176  103.061 157.763 1.00 55.69  ? 133 ASN D N   1 
ATOM   7593 C CA  . ASN D 1 59  ? 89.433  102.059 156.997 1.00 56.97  ? 133 ASN D CA  1 
ATOM   7594 C C   . ASN D 1 59  ? 89.422  102.390 155.502 1.00 57.87  ? 133 ASN D C   1 
ATOM   7595 O O   . ASN D 1 59  ? 88.374  102.609 154.891 1.00 62.28  ? 133 ASN D O   1 
ATOM   7596 C CB  . ASN D 1 59  ? 88.008  101.914 157.544 1.00 56.74  ? 133 ASN D CB  1 
ATOM   7597 C CG  . ASN D 1 59  ? 87.417  100.542 157.282 1.00 60.49  ? 133 ASN D CG  1 
ATOM   7598 O OD1 . ASN D 1 59  ? 87.724  99.901  156.277 1.00 59.63  ? 133 ASN D OD1 1 
ATOM   7599 N ND2 . ASN D 1 59  ? 86.565  100.082 158.192 1.00 62.22  ? 133 ASN D ND2 1 
ATOM   7600 N N   . MET D 1 60  ? 90.618  102.418 154.919 1.00 49.17  ? 134 MET D N   1 
ATOM   7601 C CA  . MET D 1 60  ? 90.791  102.725 153.505 1.00 44.80  ? 134 MET D CA  1 
ATOM   7602 C C   . MET D 1 60  ? 91.659  101.654 152.860 1.00 41.04  ? 134 MET D C   1 
ATOM   7603 O O   . MET D 1 60  ? 92.756  101.364 153.348 1.00 48.64  ? 134 MET D O   1 
ATOM   7604 C CB  . MET D 1 60  ? 91.402  104.119 153.325 1.00 44.73  ? 134 MET D CB  1 
ATOM   7605 C CG  . MET D 1 60  ? 91.574  104.555 151.886 1.00 47.91  ? 134 MET D CG  1 
ATOM   7606 S SD  . MET D 1 60  ? 92.264  106.212 151.767 1.00 53.64  ? 134 MET D SD  1 
ATOM   7607 C CE  . MET D 1 60  ? 93.942  105.894 152.286 1.00 50.65  ? 134 MET D CE  1 
ATOM   7608 N N   . ILE D 1 61  ? 91.164  101.072 151.766 1.00 36.01  ? 135 ILE D N   1 
ATOM   7609 C CA  . ILE D 1 61  ? 91.841  99.950  151.126 1.00 32.50  ? 135 ILE D CA  1 
ATOM   7610 C C   . ILE D 1 61  ? 93.180  100.399 150.559 1.00 39.50  ? 135 ILE D C   1 
ATOM   7611 O O   . ILE D 1 61  ? 93.292  101.468 149.942 1.00 49.64  ? 135 ILE D O   1 
ATOM   7612 C CB  . ILE D 1 61  ? 90.950  99.341  150.031 1.00 32.88  ? 135 ILE D CB  1 
ATOM   7613 C CG1 . ILE D 1 61  ? 89.504  99.249  150.516 1.00 42.41  ? 135 ILE D CG1 1 
ATOM   7614 C CG2 . ILE D 1 61  ? 91.454  97.965  149.637 1.00 36.80  ? 135 ILE D CG2 1 
ATOM   7615 C CD1 . ILE D 1 61  ? 88.569  98.596  149.526 1.00 43.49  ? 135 ILE D CD1 1 
ATOM   7616 N N   . VAL D 1 62  ? 94.207  99.579  150.769 1.00 23.77  ? 136 VAL D N   1 
ATOM   7617 C CA  . VAL D 1 62  ? 95.566  99.867  150.331 1.00 22.64  ? 136 VAL D CA  1 
ATOM   7618 C C   . VAL D 1 62  ? 96.044  98.732  149.434 1.00 31.17  ? 136 VAL D C   1 
ATOM   7619 O O   . VAL D 1 62  ? 95.757  97.559  149.694 1.00 38.86  ? 136 VAL D O   1 
ATOM   7620 C CB  . VAL D 1 62  ? 96.516  100.066 151.530 1.00 22.05  ? 136 VAL D CB  1 
ATOM   7621 C CG1 . VAL D 1 62  ? 96.092  101.268 152.346 1.00 34.17  ? 136 VAL D CG1 1 
ATOM   7622 C CG2 . VAL D 1 62  ? 96.505  98.846  152.409 1.00 36.02  ? 136 VAL D CG2 1 
ATOM   7623 N N   . TYR D 1 63  ? 96.750  99.087  148.363 1.00 39.85  ? 137 TYR D N   1 
ATOM   7624 C CA  . TYR D 1 63  ? 97.272  98.123  147.405 1.00 32.37  ? 137 TYR D CA  1 
ATOM   7625 C C   . TYR D 1 63  ? 98.793  98.151  147.419 1.00 40.85  ? 137 TYR D C   1 
ATOM   7626 O O   . TYR D 1 63  ? 99.403  99.222  147.494 1.00 50.26  ? 137 TYR D O   1 
ATOM   7627 C CB  . TYR D 1 63  ? 96.756  98.405  145.990 1.00 38.69  ? 137 TYR D CB  1 
ATOM   7628 C CG  . TYR D 1 63  ? 95.323  97.983  145.759 1.00 39.15  ? 137 TYR D CG  1 
ATOM   7629 C CD1 . TYR D 1 63  ? 94.289  98.519  146.512 1.00 38.01  ? 137 TYR D CD1 1 
ATOM   7630 C CD2 . TYR D 1 63  ? 95.005  97.053  144.779 1.00 43.43  ? 137 TYR D CD2 1 
ATOM   7631 C CE1 . TYR D 1 63  ? 92.981  98.134  146.303 1.00 39.84  ? 137 TYR D CE1 1 
ATOM   7632 C CE2 . TYR D 1 63  ? 93.699  96.665  144.561 1.00 40.21  ? 137 TYR D CE2 1 
ATOM   7633 C CZ  . TYR D 1 63  ? 92.692  97.210  145.325 1.00 37.32  ? 137 TYR D CZ  1 
ATOM   7634 O OH  . TYR D 1 63  ? 91.389  96.825  145.110 1.00 39.78  ? 137 TYR D OH  1 
ATOM   7635 N N   . VAL D 1 64  ? 99.400  96.970  147.352 1.00 41.40  ? 138 VAL D N   1 
ATOM   7636 C CA  . VAL D 1 64  ? 100.849 96.823  147.412 1.00 37.22  ? 138 VAL D CA  1 
ATOM   7637 C C   . VAL D 1 64  ? 101.278 95.800  146.367 1.00 47.46  ? 138 VAL D C   1 
ATOM   7638 O O   . VAL D 1 64  ? 100.600 94.787  146.162 1.00 54.32  ? 138 VAL D O   1 
ATOM   7639 C CB  . VAL D 1 64  ? 101.307 96.409  148.829 1.00 47.95  ? 138 VAL D CB  1 
ATOM   7640 C CG1 . VAL D 1 64  ? 102.683 95.766  148.801 1.00 53.98  ? 138 VAL D CG1 1 
ATOM   7641 C CG2 . VAL D 1 64  ? 101.299 97.608  149.762 1.00 47.35  ? 138 VAL D CG2 1 
ATOM   7642 N N   . GLU D 1 65  ? 102.395 96.075  145.696 1.00 58.94  ? 139 GLU D N   1 
ATOM   7643 C CA  . GLU D 1 65  ? 102.962 95.126  144.746 1.00 61.98  ? 139 GLU D CA  1 
ATOM   7644 C C   . GLU D 1 65  ? 103.307 93.810  145.434 1.00 69.20  ? 139 GLU D C   1 
ATOM   7645 O O   . GLU D 1 65  ? 103.772 93.790  146.577 1.00 70.19  ? 139 GLU D O   1 
ATOM   7646 C CB  . GLU D 1 65  ? 104.212 95.721  144.093 1.00 65.18  ? 139 GLU D CB  1 
ATOM   7647 C CG  . GLU D 1 65  ? 104.913 94.805  143.098 1.00 67.49  ? 139 GLU D CG  1 
ATOM   7648 C CD  . GLU D 1 65  ? 104.080 94.513  141.867 1.00 71.51  ? 139 GLU D CD  1 
ATOM   7649 O OE1 . GLU D 1 65  ? 103.229 95.353  141.511 1.00 70.82  ? 139 GLU D OE1 1 
ATOM   7650 O OE2 . GLU D 1 65  ? 104.275 93.440  141.258 1.00 71.37  ? 139 GLU D OE2 1 
ATOM   7651 N N   . LYS D 1 66  ? 103.075 92.701  144.724 1.00 69.33  ? 140 LYS D N   1 
ATOM   7652 C CA  . LYS D 1 66  ? 103.369 91.383  145.279 1.00 65.28  ? 140 LYS D CA  1 
ATOM   7653 C C   . LYS D 1 66  ? 104.847 91.240  145.617 1.00 65.66  ? 140 LYS D C   1 
ATOM   7654 O O   . LYS D 1 66  ? 105.205 90.606  146.617 1.00 69.91  ? 140 LYS D O   1 
ATOM   7655 C CB  . LYS D 1 66  ? 102.934 90.293  144.298 1.00 66.33  ? 140 LYS D CB  1 
ATOM   7656 C CG  . LYS D 1 66  ? 103.224 88.872  144.763 1.00 70.60  ? 140 LYS D CG  1 
ATOM   7657 C CD  . LYS D 1 66  ? 102.351 88.484  145.947 1.00 72.07  ? 140 LYS D CD  1 
ATOM   7658 C CE  . LYS D 1 66  ? 102.561 87.031  146.343 1.00 69.37  ? 140 LYS D CE  1 
ATOM   7659 N NZ  . LYS D 1 66  ? 101.756 86.660  147.541 1.00 68.10  ? 140 LYS D NZ  1 
ATOM   7660 N N   . LYS D 1 67  ? 105.722 91.823  144.795 1.00 65.47  ? 141 LYS D N   1 
ATOM   7661 C CA  . LYS D 1 67  ? 107.156 91.727  145.039 1.00 65.11  ? 141 LYS D CA  1 
ATOM   7662 C C   . LYS D 1 67  ? 107.587 92.472  146.296 1.00 66.18  ? 141 LYS D C   1 
ATOM   7663 O O   . LYS D 1 67  ? 108.700 92.247  146.782 1.00 69.06  ? 141 LYS D O   1 
ATOM   7664 C CB  . LYS D 1 67  ? 107.927 92.258  143.829 1.00 67.19  ? 141 LYS D CB  1 
ATOM   7665 C CG  . LYS D 1 67  ? 108.141 91.227  142.734 1.00 67.93  ? 141 LYS D CG  1 
ATOM   7666 C CD  . LYS D 1 67  ? 108.925 91.806  141.569 1.00 69.83  ? 141 LYS D CD  1 
ATOM   7667 C CE  . LYS D 1 67  ? 109.521 90.706  140.706 1.00 69.08  ? 141 LYS D CE  1 
ATOM   7668 N NZ  . LYS D 1 67  ? 109.412 91.020  139.254 1.00 68.76  ? 141 LYS D NZ  1 
ATOM   7669 N N   . VAL D 1 68  ? 106.738 93.349  146.832 1.00 62.27  ? 142 VAL D N   1 
ATOM   7670 C CA  . VAL D 1 68  ? 107.095 94.081  148.043 1.00 63.94  ? 142 VAL D CA  1 
ATOM   7671 C C   . VAL D 1 68  ? 106.835 93.234  149.283 1.00 67.44  ? 142 VAL D C   1 
ATOM   7672 O O   . VAL D 1 68  ? 107.621 93.252  150.236 1.00 69.54  ? 142 VAL D O   1 
ATOM   7673 C CB  . VAL D 1 68  ? 106.333 95.418  148.096 1.00 66.20  ? 142 VAL D CB  1 
ATOM   7674 C CG1 . VAL D 1 68  ? 106.707 96.197  149.347 1.00 65.24  ? 142 VAL D CG1 1 
ATOM   7675 C CG2 . VAL D 1 68  ? 106.618 96.238  146.850 1.00 66.42  ? 142 VAL D CG2 1 
ATOM   7676 N N   . LEU D 1 69  ? 105.736 92.476  149.290 1.00 67.62  ? 143 LEU D N   1 
ATOM   7677 C CA  . LEU D 1 69  ? 105.402 91.659  150.450 1.00 68.89  ? 143 LEU D CA  1 
ATOM   7678 C C   . LEU D 1 69  ? 106.291 90.430  150.579 1.00 71.09  ? 143 LEU D C   1 
ATOM   7679 O O   . LEU D 1 69  ? 106.401 89.875  151.677 1.00 70.62  ? 143 LEU D O   1 
ATOM   7680 C CB  . LEU D 1 69  ? 103.935 91.239  150.389 1.00 67.14  ? 143 LEU D CB  1 
ATOM   7681 C CG  . LEU D 1 69  ? 102.956 92.407  150.478 1.00 66.66  ? 143 LEU D CG  1 
ATOM   7682 C CD1 . LEU D 1 69  ? 101.542 91.910  150.718 1.00 67.76  ? 143 LEU D CD1 1 
ATOM   7683 C CD2 . LEU D 1 69  ? 103.395 93.364  151.574 1.00 66.28  ? 143 LEU D CD2 1 
ATOM   7684 N N   . GLU D 1 70  ? 106.924 89.993  149.493 1.00 69.28  ? 144 GLU D N   1 
ATOM   7685 C CA  . GLU D 1 70  ? 107.826 88.851  149.547 1.00 66.79  ? 144 GLU D CA  1 
ATOM   7686 C C   . GLU D 1 70  ? 109.237 89.237  149.968 1.00 68.41  ? 144 GLU D C   1 
ATOM   7687 O O   . GLU D 1 70  ? 110.113 88.367  150.010 1.00 71.01  ? 144 GLU D O   1 
ATOM   7688 C CB  . GLU D 1 70  ? 107.867 88.143  148.191 1.00 68.96  ? 144 GLU D CB  1 
ATOM   7689 C CG  . GLU D 1 70  ? 108.505 88.960  147.082 1.00 71.48  ? 144 GLU D CG  1 
ATOM   7690 C CD  . GLU D 1 70  ? 108.492 88.241  145.748 1.00 73.91  ? 144 GLU D CD  1 
ATOM   7691 O OE1 . GLU D 1 70  ? 107.959 87.113  145.686 1.00 73.37  ? 144 GLU D OE1 1 
ATOM   7692 O OE2 . GLU D 1 70  ? 109.015 88.802  144.762 1.00 73.81  ? 144 GLU D OE2 1 
ATOM   7693 N N   . ASP D 1 71  ? 109.475 90.508  150.268 1.00 65.55  ? 145 ASP D N   1 
ATOM   7694 C CA  . ASP D 1 71  ? 110.796 90.945  150.692 1.00 66.12  ? 145 ASP D CA  1 
ATOM   7695 C C   . ASP D 1 71  ? 111.149 90.311  152.035 1.00 67.47  ? 145 ASP D C   1 
ATOM   7696 O O   . ASP D 1 71  ? 110.293 90.244  152.928 1.00 67.67  ? 145 ASP D O   1 
ATOM   7697 C CB  . ASP D 1 71  ? 110.842 92.468  150.795 1.00 67.76  ? 145 ASP D CB  1 
ATOM   7698 C CG  . ASP D 1 71  ? 112.231 92.991  151.096 1.00 69.49  ? 145 ASP D CG  1 
ATOM   7699 O OD1 . ASP D 1 71  ? 113.083 92.981  150.183 1.00 68.80  ? 145 ASP D OD1 1 
ATOM   7700 O OD2 . ASP D 1 71  ? 112.470 93.417  152.244 1.00 69.97  ? 145 ASP D OD2 1 
ATOM   7701 N N   . PRO D 1 72  ? 112.377 89.818  152.212 1.00 71.38  ? 146 PRO D N   1 
ATOM   7702 C CA  . PRO D 1 72  ? 112.746 89.211  153.502 1.00 69.64  ? 146 PRO D CA  1 
ATOM   7703 C C   . PRO D 1 72  ? 112.652 90.164  154.682 1.00 68.17  ? 146 PRO D C   1 
ATOM   7704 O O   . PRO D 1 72  ? 112.399 89.708  155.804 1.00 71.04  ? 146 PRO D O   1 
ATOM   7705 C CB  . PRO D 1 72  ? 114.192 88.753  153.271 1.00 69.68  ? 146 PRO D CB  1 
ATOM   7706 C CG  . PRO D 1 72  ? 114.294 88.562  151.795 1.00 70.59  ? 146 PRO D CG  1 
ATOM   7707 C CD  . PRO D 1 72  ? 113.416 89.620  151.188 1.00 71.21  ? 146 PRO D CD  1 
ATOM   7708 N N   . ALA D 1 73  ? 112.844 91.465  154.471 1.00 61.02  ? 147 ALA D N   1 
ATOM   7709 C CA  . ALA D 1 73  ? 112.870 92.423  155.569 1.00 60.74  ? 147 ALA D CA  1 
ATOM   7710 C C   . ALA D 1 73  ? 111.484 92.880  156.003 1.00 60.24  ? 147 ALA D C   1 
ATOM   7711 O O   . ALA D 1 73  ? 111.381 93.644  156.969 1.00 62.17  ? 147 ALA D O   1 
ATOM   7712 C CB  . ALA D 1 73  ? 113.716 93.640  155.186 1.00 60.03  ? 147 ALA D CB  1 
ATOM   7713 N N   . ILE D 1 74  ? 110.424 92.442  155.326 1.00 60.75  ? 148 ILE D N   1 
ATOM   7714 C CA  . ILE D 1 74  ? 109.071 92.797  155.717 1.00 61.23  ? 148 ILE D CA  1 
ATOM   7715 C C   . ILE D 1 74  ? 108.298 91.605  156.275 1.00 62.52  ? 148 ILE D C   1 
ATOM   7716 O O   . ILE D 1 74  ? 107.406 91.798  157.110 1.00 65.46  ? 148 ILE D O   1 
ATOM   7717 C CB  . ILE D 1 74  ? 108.309 93.444  154.538 1.00 62.95  ? 148 ILE D CB  1 
ATOM   7718 C CG1 . ILE D 1 74  ? 106.988 94.052  155.009 1.00 62.22  ? 148 ILE D CG1 1 
ATOM   7719 C CG2 . ILE D 1 74  ? 108.058 92.435  153.431 1.00 64.76  ? 148 ILE D CG2 1 
ATOM   7720 C CD1 . ILE D 1 74  ? 106.348 94.971  153.992 1.00 64.00  ? 148 ILE D CD1 1 
ATOM   7721 N N   . ALA D 1 75  ? 108.623 90.380  155.855 1.00 65.44  ? 149 ALA D N   1 
ATOM   7722 C CA  . ALA D 1 75  ? 108.019 89.197  156.458 1.00 64.78  ? 149 ALA D CA  1 
ATOM   7723 C C   . ALA D 1 75  ? 108.675 88.847  157.789 1.00 65.05  ? 149 ALA D C   1 
ATOM   7724 O O   . ALA D 1 75  ? 108.032 88.225  158.644 1.00 63.74  ? 149 ALA D O   1 
ATOM   7725 C CB  . ALA D 1 75  ? 108.101 88.017  155.501 1.00 64.28  ? 149 ALA D CB  1 
ATOM   7726 N N   . SER D 1 76  ? 109.935 89.241  157.992 1.00 68.79  ? 150 SER D N   1 
ATOM   7727 C CA  . SER D 1 76  ? 110.622 88.927  159.240 1.00 68.11  ? 150 SER D CA  1 
ATOM   7728 C C   . SER D 1 76  ? 109.966 89.621  160.426 1.00 68.54  ? 150 SER D C   1 
ATOM   7729 O O   . SER D 1 76  ? 109.801 89.018  161.494 1.00 70.64  ? 150 SER D O   1 
ATOM   7730 C CB  . SER D 1 76  ? 112.096 89.319  159.138 1.00 68.43  ? 150 SER D CB  1 
ATOM   7731 O OG  . SER D 1 76  ? 112.680 88.808  157.953 1.00 70.54  ? 150 SER D OG  1 
ATOM   7732 N N   . ASP D 1 77  ? 109.588 90.886  160.263 1.00 65.55  ? 151 ASP D N   1 
ATOM   7733 C CA  . ASP D 1 77  ? 108.960 91.622  161.350 1.00 68.43  ? 151 ASP D CA  1 
ATOM   7734 C C   . ASP D 1 77  ? 107.538 91.121  161.568 1.00 68.14  ? 151 ASP D C   1 
ATOM   7735 O O   . ASP D 1 77  ? 106.749 91.026  160.623 1.00 68.61  ? 151 ASP D O   1 
ATOM   7736 C CB  . ASP D 1 77  ? 108.956 93.119  161.045 1.00 68.67  ? 151 ASP D CB  1 
ATOM   7737 C CG  . ASP D 1 77  ? 108.294 93.938  162.138 1.00 71.29  ? 151 ASP D CG  1 
ATOM   7738 O OD1 . ASP D 1 77  ? 108.255 93.471  163.296 1.00 69.10  ? 151 ASP D OD1 1 
ATOM   7739 O OD2 . ASP D 1 77  ? 107.814 95.051  161.838 1.00 71.83  ? 151 ASP D OD2 1 
ATOM   7740 N N   . GLU D 1 78  ? 107.213 90.798  162.820 1.00 69.41  ? 152 GLU D N   1 
ATOM   7741 C CA  . GLU D 1 78  ? 105.888 90.302  163.164 1.00 69.51  ? 152 GLU D CA  1 
ATOM   7742 C C   . GLU D 1 78  ? 104.949 91.391  163.662 1.00 69.11  ? 152 GLU D C   1 
ATOM   7743 O O   . GLU D 1 78  ? 103.728 91.203  163.608 1.00 72.40  ? 152 GLU D O   1 
ATOM   7744 C CB  . GLU D 1 78  ? 105.991 89.201  164.228 1.00 69.83  ? 152 GLU D CB  1 
ATOM   7745 C CG  . GLU D 1 78  ? 106.427 89.689  165.602 1.00 72.74  ? 152 GLU D CG  1 
ATOM   7746 C CD  . GLU D 1 78  ? 107.936 89.750  165.754 1.00 75.79  ? 152 GLU D CD  1 
ATOM   7747 O OE1 . GLU D 1 78  ? 108.645 89.700  164.727 1.00 76.89  ? 152 GLU D OE1 1 
ATOM   7748 O OE2 . GLU D 1 78  ? 108.414 89.848  166.904 1.00 72.87  ? 152 GLU D OE2 1 
ATOM   7749 N N   . SER D 1 79  ? 105.482 92.514  164.149 1.00 59.31  ? 153 SER D N   1 
ATOM   7750 C CA  . SER D 1 79  ? 104.622 93.617  164.563 1.00 63.60  ? 153 SER D CA  1 
ATOM   7751 C C   . SER D 1 79  ? 103.863 94.195  163.376 1.00 64.09  ? 153 SER D C   1 
ATOM   7752 O O   . SER D 1 79  ? 102.664 94.481  163.474 1.00 62.49  ? 153 SER D O   1 
ATOM   7753 C CB  . SER D 1 79  ? 105.451 94.699  165.253 1.00 63.85  ? 153 SER D CB  1 
ATOM   7754 O OG  . SER D 1 79  ? 106.355 95.304  164.346 1.00 66.29  ? 153 SER D OG  1 
ATOM   7755 N N   . PHE D 1 80  ? 104.547 94.374  162.245 1.00 60.86  ? 154 PHE D N   1 
ATOM   7756 C CA  . PHE D 1 80  ? 103.896 94.860  161.036 1.00 59.27  ? 154 PHE D CA  1 
ATOM   7757 C C   . PHE D 1 80  ? 103.088 93.779  160.332 1.00 60.34  ? 154 PHE D C   1 
ATOM   7758 O O   . PHE D 1 80  ? 102.198 94.106  159.540 1.00 66.63  ? 154 PHE D O   1 
ATOM   7759 C CB  . PHE D 1 80  ? 104.939 95.433  160.074 1.00 59.17  ? 154 PHE D CB  1 
ATOM   7760 C CG  . PHE D 1 80  ? 104.348 96.086  158.858 1.00 57.89  ? 154 PHE D CG  1 
ATOM   7761 C CD1 . PHE D 1 80  ? 103.508 97.178  158.982 1.00 59.54  ? 154 PHE D CD1 1 
ATOM   7762 C CD2 . PHE D 1 80  ? 104.628 95.603  157.592 1.00 57.44  ? 154 PHE D CD2 1 
ATOM   7763 C CE1 . PHE D 1 80  ? 102.961 97.780  157.867 1.00 59.90  ? 154 PHE D CE1 1 
ATOM   7764 C CE2 . PHE D 1 80  ? 104.084 96.201  156.472 1.00 59.28  ? 154 PHE D CE2 1 
ATOM   7765 C CZ  . PHE D 1 80  ? 103.250 97.291  156.610 1.00 59.60  ? 154 PHE D CZ  1 
ATOM   7766 N N   . GLY D 1 81  ? 103.372 92.504  160.606 1.00 53.44  ? 155 GLY D N   1 
ATOM   7767 C CA  . GLY D 1 81  ? 102.658 91.433  159.934 1.00 52.96  ? 155 GLY D CA  1 
ATOM   7768 C C   . GLY D 1 81  ? 101.198 91.345  160.325 1.00 52.74  ? 155 GLY D C   1 
ATOM   7769 O O   . GLY D 1 81  ? 100.379 90.824  159.562 1.00 54.38  ? 155 GLY D O   1 
ATOM   7770 N N   . ALA D 1 82  ? 100.850 91.842  161.514 1.00 51.08  ? 156 ALA D N   1 
ATOM   7771 C CA  . ALA D 1 82  ? 99.455  91.821  161.943 1.00 54.69  ? 156 ALA D CA  1 
ATOM   7772 C C   . ALA D 1 82  ? 98.590  92.701  161.050 1.00 51.18  ? 156 ALA D C   1 
ATOM   7773 O O   . ALA D 1 82  ? 97.455  92.337  160.722 1.00 51.10  ? 156 ALA D O   1 
ATOM   7774 C CB  . ALA D 1 82  ? 99.347  92.263  163.402 1.00 54.66  ? 156 ALA D CB  1 
ATOM   7775 N N   . VAL D 1 83  ? 99.110  93.863  160.647 1.00 52.89  ? 157 VAL D N   1 
ATOM   7776 C CA  . VAL D 1 83  ? 98.357  94.777  159.795 1.00 54.43  ? 157 VAL D CA  1 
ATOM   7777 C C   . VAL D 1 83  ? 98.678  94.579  158.319 1.00 50.63  ? 157 VAL D C   1 
ATOM   7778 O O   . VAL D 1 83  ? 97.958  95.110  157.459 1.00 53.37  ? 157 VAL D O   1 
ATOM   7779 C CB  . VAL D 1 83  ? 98.628  96.235  160.224 1.00 54.06  ? 157 VAL D CB  1 
ATOM   7780 C CG1 . VAL D 1 83  ? 100.015 96.682  159.778 1.00 51.05  ? 157 VAL D CG1 1 
ATOM   7781 C CG2 . VAL D 1 83  ? 97.533  97.174  159.737 1.00 52.82  ? 157 VAL D CG2 1 
ATOM   7782 N N   . LYS D 1 84  ? 99.726  93.818  157.996 1.00 50.73  ? 158 LYS D N   1 
ATOM   7783 C CA  . LYS D 1 84  ? 100.084 93.563  156.605 1.00 49.95  ? 158 LYS D CA  1 
ATOM   7784 C C   . LYS D 1 84  ? 99.077  92.663  155.899 1.00 47.74  ? 158 LYS D C   1 
ATOM   7785 O O   . LYS D 1 84  ? 98.953  92.733  154.672 1.00 51.50  ? 158 LYS D O   1 
ATOM   7786 C CB  . LYS D 1 84  ? 101.483 92.943  156.539 1.00 48.41  ? 158 LYS D CB  1 
ATOM   7787 C CG  . LYS D 1 84  ? 101.991 92.667  155.133 1.00 51.81  ? 158 LYS D CG  1 
ATOM   7788 C CD  . LYS D 1 84  ? 103.427 92.180  155.149 1.00 51.33  ? 158 LYS D CD  1 
ATOM   7789 C CE  . LYS D 1 84  ? 103.520 90.756  155.660 1.00 51.08  ? 158 LYS D CE  1 
ATOM   7790 N NZ  . LYS D 1 84  ? 104.910 90.239  155.565 1.00 55.89  ? 158 LYS D NZ  1 
ATOM   7791 N N   . LYS D 1 85  ? 98.341  91.837  156.645 1.00 49.30  ? 159 LYS D N   1 
ATOM   7792 C CA  . LYS D 1 85  ? 97.399  90.902  156.042 1.00 48.92  ? 159 LYS D CA  1 
ATOM   7793 C C   . LYS D 1 85  ? 96.218  91.593  155.375 1.00 49.35  ? 159 LYS D C   1 
ATOM   7794 O O   . LYS D 1 85  ? 95.469  90.932  154.648 1.00 54.24  ? 159 LYS D O   1 
ATOM   7795 C CB  . LYS D 1 85  ? 96.889  89.920  157.098 1.00 51.18  ? 159 LYS D CB  1 
ATOM   7796 C CG  . LYS D 1 85  ? 95.951  88.854  156.554 1.00 52.98  ? 159 LYS D CG  1 
ATOM   7797 C CD  . LYS D 1 85  ? 95.522  87.886  157.644 1.00 52.44  ? 159 LYS D CD  1 
ATOM   7798 C CE  . LYS D 1 85  ? 94.566  86.835  157.106 1.00 54.09  ? 159 LYS D CE  1 
ATOM   7799 N NZ  . LYS D 1 85  ? 94.138  85.880  158.164 1.00 54.42  ? 159 LYS D NZ  1 
ATOM   7800 N N   . LYS D 1 86  ? 96.030  92.895  155.601 1.00 39.22  ? 160 LYS D N   1 
ATOM   7801 C CA  . LYS D 1 86  ? 94.939  93.648  154.995 1.00 41.72  ? 160 LYS D CA  1 
ATOM   7802 C C   . LYS D 1 86  ? 95.351  94.336  153.698 1.00 46.59  ? 160 LYS D C   1 
ATOM   7803 O O   . LYS D 1 86  ? 94.814  95.401  153.366 1.00 48.94  ? 160 LYS D O   1 
ATOM   7804 C CB  . LYS D 1 86  ? 94.393  94.669  155.992 1.00 45.41  ? 160 LYS D CB  1 
ATOM   7805 C CG  . LYS D 1 86  ? 94.078  94.086  157.359 1.00 47.21  ? 160 LYS D CG  1 
ATOM   7806 C CD  . LYS D 1 86  ? 94.077  95.159  158.433 1.00 45.11  ? 160 LYS D CD  1 
ATOM   7807 C CE  . LYS D 1 86  ? 93.019  96.213  158.157 1.00 46.06  ? 160 LYS D CE  1 
ATOM   7808 N NZ  . LYS D 1 86  ? 93.037  97.297  159.177 1.00 45.26  ? 160 LYS D NZ  1 
ATOM   7809 N N   . PHE D 1 87  ? 96.291  93.757  152.958 1.00 42.44  ? 161 PHE D N   1 
ATOM   7810 C CA  . PHE D 1 87  ? 96.776  94.323  151.708 1.00 33.53  ? 161 PHE D CA  1 
ATOM   7811 C C   . PHE D 1 87  ? 96.037  93.689  150.536 1.00 41.09  ? 161 PHE D C   1 
ATOM   7812 O O   . PHE D 1 87  ? 95.954  92.460  150.442 1.00 50.04  ? 161 PHE D O   1 
ATOM   7813 C CB  . PHE D 1 87  ? 98.281  94.099  151.557 1.00 38.24  ? 161 PHE D CB  1 
ATOM   7814 C CG  . PHE D 1 87  ? 99.124  95.054  152.352 1.00 36.06  ? 161 PHE D CG  1 
ATOM   7815 C CD1 . PHE D 1 87  ? 98.592  96.230  152.841 1.00 45.08  ? 161 PHE D CD1 1 
ATOM   7816 C CD2 . PHE D 1 87  ? 100.453 94.775  152.607 1.00 39.70  ? 161 PHE D CD2 1 
ATOM   7817 C CE1 . PHE D 1 87  ? 99.369  97.110  153.570 1.00 45.57  ? 161 PHE D CE1 1 
ATOM   7818 C CE2 . PHE D 1 87  ? 101.235 95.650  153.334 1.00 42.01  ? 161 PHE D CE2 1 
ATOM   7819 C CZ  . PHE D 1 87  ? 100.692 96.818  153.817 1.00 42.61  ? 161 PHE D CZ  1 
ATOM   7820 N N   . THR D 1 88  ? 95.505  94.528  149.646 1.00 38.53  ? 162 THR D N   1 
ATOM   7821 C CA  . THR D 1 88  ? 94.872  94.055  148.415 1.00 38.48  ? 162 THR D CA  1 
ATOM   7822 C C   . THR D 1 88  ? 95.973  93.840  147.380 1.00 40.68  ? 162 THR D C   1 
ATOM   7823 O O   . THR D 1 88  ? 96.202  94.649  146.478 1.00 48.17  ? 162 THR D O   1 
ATOM   7824 C CB  . THR D 1 88  ? 93.819  95.055  147.902 1.00 45.84  ? 162 THR D CB  1 
ATOM   7825 O OG1 . THR D 1 88  ? 92.790  95.215  148.884 1.00 49.16  ? 162 THR D OG1 1 
ATOM   7826 C CG2 . THR D 1 88  ? 93.076  94.481  146.705 1.00 46.32  ? 162 THR D CG2 1 
ATOM   7827 N N   . THR D 1 89  ? 96.666  92.715  147.525 1.00 55.10  ? 163 THR D N   1 
ATOM   7828 C CA  . THR D 1 89  ? 97.873  92.462  146.752 1.00 56.09  ? 163 THR D CA  1 
ATOM   7829 C C   . THR D 1 89  ? 97.543  92.130  145.301 1.00 57.95  ? 163 THR D C   1 
ATOM   7830 O O   . THR D 1 89  ? 96.566  91.434  145.010 1.00 62.71  ? 163 THR D O   1 
ATOM   7831 C CB  . THR D 1 89  ? 98.664  91.317  147.388 1.00 58.90  ? 163 THR D CB  1 
ATOM   7832 O OG1 . THR D 1 89  ? 98.982  91.654  148.743 1.00 59.46  ? 163 THR D OG1 1 
ATOM   7833 C CG2 . THR D 1 89  ? 99.955  91.067  146.632 1.00 58.35  ? 163 THR D CG2 1 
ATOM   7834 N N   . PHE D 1 90  ? 98.368  92.640  144.388 1.00 71.10  ? 164 PHE D N   1 
ATOM   7835 C CA  . PHE D 1 90  ? 98.296  92.309  142.973 1.00 74.04  ? 164 PHE D CA  1 
ATOM   7836 C C   . PHE D 1 90  ? 99.687  91.927  142.485 1.00 74.96  ? 164 PHE D C   1 
ATOM   7837 O O   . PHE D 1 90  ? 100.692 92.499  142.916 1.00 71.56  ? 164 PHE D O   1 
ATOM   7838 C CB  . PHE D 1 90  ? 97.726  93.478  142.152 1.00 67.21  ? 164 PHE D CB  1 
ATOM   7839 C CG  . PHE D 1 90  ? 98.609  94.692  142.124 1.00 66.01  ? 164 PHE D CG  1 
ATOM   7840 C CD1 . PHE D 1 90  ? 98.536  95.639  143.131 1.00 69.58  ? 164 PHE D CD1 1 
ATOM   7841 C CD2 . PHE D 1 90  ? 99.495  94.899  141.080 1.00 68.28  ? 164 PHE D CD2 1 
ATOM   7842 C CE1 . PHE D 1 90  ? 99.343  96.758  143.109 1.00 72.35  ? 164 PHE D CE1 1 
ATOM   7843 C CE2 . PHE D 1 90  ? 100.302 96.018  141.051 1.00 71.51  ? 164 PHE D CE2 1 
ATOM   7844 C CZ  . PHE D 1 90  ? 100.227 96.948  142.067 1.00 72.66  ? 164 PHE D CZ  1 
ATOM   7845 N N   . ARG D 1 91  ? 99.737  90.950  141.579 1.00 86.52  ? 165 ARG D N   1 
ATOM   7846 C CA  . ARG D 1 91  ? 100.997 90.336  141.176 1.00 85.70  ? 165 ARG D CA  1 
ATOM   7847 C C   . ARG D 1 91  ? 101.583 90.912  139.893 1.00 86.15  ? 165 ARG D C   1 
ATOM   7848 O O   . ARG D 1 91  ? 102.697 90.526  139.521 1.00 86.43  ? 165 ARG D O   1 
ATOM   7849 C CB  . ARG D 1 91  ? 100.808 88.826  141.014 1.00 86.06  ? 165 ARG D CB  1 
ATOM   7850 C CG  . ARG D 1 91  ? 100.542 88.091  142.317 1.00 85.68  ? 165 ARG D CG  1 
ATOM   7851 C CD  . ARG D 1 91  ? 100.188 86.623  142.141 1.00 86.81  ? 165 ARG D CD  1 
ATOM   7852 N NE  . ARG D 1 91  ? 98.934  86.445  141.415 1.00 88.41  ? 165 ARG D NE  1 
ATOM   7853 C CZ  . ARG D 1 91  ? 98.401  85.267  141.128 1.00 88.28  ? 165 ARG D CZ  1 
ATOM   7854 N NH1 . ARG D 1 91  ? 99.008  84.150  141.510 1.00 86.27  ? 165 ARG D NH1 1 
ATOM   7855 N NH2 . ARG D 1 91  ? 97.255  85.199  140.462 1.00 87.80  ? 165 ARG D NH2 1 
ATOM   7856 N N   . GLU D 1 92  ? 100.850 91.782  139.193 1.00 80.81  ? 166 GLU D N   1 
ATOM   7857 C CA  . GLU D 1 92  ? 101.331 92.501  138.013 1.00 80.91  ? 166 GLU D CA  1 
ATOM   7858 C C   . GLU D 1 92  ? 101.494 91.579  136.806 1.00 83.92  ? 166 GLU D C   1 
ATOM   7859 O O   . GLU D 1 92  ? 101.746 92.050  135.691 1.00 83.19  ? 166 GLU D O   1 
ATOM   7860 C CB  . GLU D 1 92  ? 102.653 93.221  138.318 1.00 80.78  ? 166 GLU D CB  1 
ATOM   7861 C CG  . GLU D 1 92  ? 103.059 94.278  137.298 1.00 81.32  ? 166 GLU D CG  1 
ATOM   7862 C CD  . GLU D 1 92  ? 104.280 95.067  137.727 1.00 81.14  ? 166 GLU D CD  1 
ATOM   7863 O OE1 . GLU D 1 92  ? 104.831 94.775  138.809 1.00 81.47  ? 166 GLU D OE1 1 
ATOM   7864 O OE2 . GLU D 1 92  ? 104.695 95.976  136.978 1.00 79.45  ? 166 GLU D OE2 1 
ATOM   7865 N N   . ASP D 1 93  ? 101.337 90.268  137.003 1.00 98.44  ? 167 ASP D N   1 
ATOM   7866 C CA  . ASP D 1 93  ? 101.460 89.342  135.881 1.00 98.59  ? 167 ASP D CA  1 
ATOM   7867 C C   . ASP D 1 93  ? 100.272 89.468  134.935 1.00 97.57  ? 167 ASP D C   1 
ATOM   7868 O O   . ASP D 1 93  ? 100.443 89.558  133.714 1.00 96.72  ? 167 ASP D O   1 
ATOM   7869 C CB  . ASP D 1 93  ? 101.596 87.907  136.393 1.00 97.02  ? 167 ASP D CB  1 
ATOM   7870 C CG  . ASP D 1 93  ? 102.645 87.772  137.478 1.00 97.26  ? 167 ASP D CG  1 
ATOM   7871 O OD1 . ASP D 1 93  ? 103.823 88.093  137.212 1.00 96.53  ? 167 ASP D OD1 1 
ATOM   7872 O OD2 . ASP D 1 93  ? 102.295 87.337  138.595 1.00 96.78  ? 167 ASP D OD2 1 
ATOM   7873 N N   . TYR D 1 94  ? 99.056  89.477  135.484 1.00 100.99 ? 168 TYR D N   1 
ATOM   7874 C CA  . TYR D 1 94  ? 97.858  89.647  134.673 1.00 101.32 ? 168 TYR D CA  1 
ATOM   7875 C C   . TYR D 1 94  ? 96.818  90.534  135.348 1.00 101.60 ? 168 TYR D C   1 
ATOM   7876 O O   . TYR D 1 94  ? 95.691  90.630  134.846 1.00 101.35 ? 168 TYR D O   1 
ATOM   7877 C CB  . TYR D 1 94  ? 97.243  88.285  134.348 1.00 101.31 ? 168 TYR D CB  1 
ATOM   7878 C CG  . TYR D 1 94  ? 98.127  87.400  133.497 1.00 102.53 ? 168 TYR D CG  1 
ATOM   7879 C CD1 . TYR D 1 94  ? 98.835  87.922  132.422 1.00 102.31 ? 168 TYR D CD1 1 
ATOM   7880 C CD2 . TYR D 1 94  ? 98.252  86.046  133.771 1.00 102.29 ? 168 TYR D CD2 1 
ATOM   7881 C CE1 . TYR D 1 94  ? 99.643  87.117  131.643 1.00 102.67 ? 168 TYR D CE1 1 
ATOM   7882 C CE2 . TYR D 1 94  ? 99.059  85.232  132.996 1.00 102.79 ? 168 TYR D CE2 1 
ATOM   7883 C CZ  . TYR D 1 94  ? 99.752  85.773  131.934 1.00 103.47 ? 168 TYR D CZ  1 
ATOM   7884 O OH  . TYR D 1 94  ? 100.555 84.968  131.159 1.00 101.34 ? 168 TYR D OH  1 
ATOM   7885 N N   . ASP D 1 95  ? 97.156  91.182  136.461 1.00 91.80  ? 169 ASP D N   1 
ATOM   7886 C CA  . ASP D 1 95  ? 96.194  91.986  137.204 1.00 90.69  ? 169 ASP D CA  1 
ATOM   7887 C C   . ASP D 1 95  ? 96.095  93.376  136.588 1.00 87.58  ? 169 ASP D C   1 
ATOM   7888 O O   . ASP D 1 95  ? 97.112  94.046  136.383 1.00 86.19  ? 169 ASP D O   1 
ATOM   7889 C CB  . ASP D 1 95  ? 96.601  92.076  138.672 1.00 89.95  ? 169 ASP D CB  1 
ATOM   7890 C CG  . ASP D 1 95  ? 96.479  90.748  139.393 1.00 89.75  ? 169 ASP D CG  1 
ATOM   7891 O OD1 . ASP D 1 95  ? 95.613  89.937  139.004 1.00 88.98  ? 169 ASP D OD1 1 
ATOM   7892 O OD2 . ASP D 1 95  ? 97.249  90.516  140.348 1.00 89.04  ? 169 ASP D OD2 1 
ATOM   7893 N N   . ASP D 1 96  ? 94.870  93.807  136.293 1.00 82.74  ? 170 ASP D N   1 
ATOM   7894 C CA  . ASP D 1 96  ? 94.607  95.146  135.768 1.00 84.03  ? 170 ASP D CA  1 
ATOM   7895 C C   . ASP D 1 96  ? 94.038  95.988  136.907 1.00 84.34  ? 170 ASP D C   1 
ATOM   7896 O O   . ASP D 1 96  ? 92.859  95.895  137.251 1.00 84.36  ? 170 ASP D O   1 
ATOM   7897 C CB  . ASP D 1 96  ? 93.668  95.086  134.566 1.00 83.41  ? 170 ASP D CB  1 
ATOM   7898 C CG  . ASP D 1 96  ? 92.405  94.295  134.846 1.00 84.04  ? 170 ASP D CG  1 
ATOM   7899 O OD1 . ASP D 1 96  ? 92.513  93.091  135.161 1.00 85.37  ? 170 ASP D OD1 1 
ATOM   7900 O OD2 . ASP D 1 96  ? 91.305  94.878  134.753 1.00 81.05  ? 170 ASP D OD2 1 
ATOM   7901 N N   . ILE D 1 97  ? 94.895  96.816  137.500 1.00 72.76  ? 171 ILE D N   1 
ATOM   7902 C CA  . ILE D 1 97  ? 94.509  97.667  138.620 1.00 71.88  ? 171 ILE D CA  1 
ATOM   7903 C C   . ILE D 1 97  ? 94.131  99.048  138.102 1.00 70.45  ? 171 ILE D C   1 
ATOM   7904 O O   . ILE D 1 97  ? 94.058  100.013 138.871 1.00 69.08  ? 171 ILE D O   1 
ATOM   7905 C CB  . ILE D 1 97  ? 95.636  97.760  139.664 1.00 71.38  ? 171 ILE D CB  1 
ATOM   7906 C CG1 . ILE D 1 97  ? 96.888  98.378  139.039 1.00 68.04  ? 171 ILE D CG1 1 
ATOM   7907 C CG2 . ILE D 1 97  ? 95.943  96.385  140.239 1.00 71.97  ? 171 ILE D CG2 1 
ATOM   7908 C CD1 . ILE D 1 97  ? 97.956  98.737  140.042 1.00 67.36  ? 171 ILE D CD1 1 
ATOM   7909 N N   . SER D 1 98  ? 93.895  99.149  136.791 1.00 70.84  ? 172 SER D N   1 
ATOM   7910 C CA  . SER D 1 98  ? 93.595  100.443 136.185 1.00 71.07  ? 172 SER D CA  1 
ATOM   7911 C C   . SER D 1 98  ? 92.301  101.032 136.734 1.00 71.63  ? 172 SER D C   1 
ATOM   7912 O O   . SER D 1 98  ? 92.217  102.241 136.981 1.00 75.57  ? 172 SER D O   1 
ATOM   7913 C CB  . SER D 1 98  ? 93.519  100.304 134.665 1.00 73.25  ? 172 SER D CB  1 
ATOM   7914 O OG  . SER D 1 98  ? 94.736  99.802  134.139 1.00 70.81  ? 172 SER D OG  1 
ATOM   7915 N N   . ASN D 1 99  ? 91.283  100.198 136.934 1.00 71.93  ? 173 ASN D N   1 
ATOM   7916 C CA  . ASN D 1 99  ? 89.989  100.682 137.400 1.00 73.31  ? 173 ASN D CA  1 
ATOM   7917 C C   . ASN D 1 99  ? 89.733  100.269 138.844 1.00 75.84  ? 173 ASN D C   1 
ATOM   7918 O O   . ASN D 1 99  ? 88.603  99.926  139.206 1.00 77.51  ? 173 ASN D O   1 
ATOM   7919 C CB  . ASN D 1 99  ? 88.870  100.164 136.493 1.00 73.11  ? 173 ASN D CB  1 
ATOM   7920 C CG  . ASN D 1 99  ? 88.998  98.683  136.198 1.00 77.00  ? 173 ASN D CG  1 
ATOM   7921 O OD1 . ASN D 1 99  ? 89.933  98.025  136.654 1.00 78.07  ? 173 ASN D OD1 1 
ATOM   7922 N ND2 . ASN D 1 99  ? 88.056  98.149  135.428 1.00 73.74  ? 173 ASN D ND2 1 
ATOM   7923 N N   . GLN D 1 100 ? 90.775  100.297 139.673 1.00 66.20  ? 174 GLN D N   1 
ATOM   7924 C CA  . GLN D 1 100 ? 90.628  99.894  141.066 1.00 61.05  ? 174 GLN D CA  1 
ATOM   7925 C C   . GLN D 1 100 ? 91.316  100.824 142.055 1.00 60.01  ? 174 GLN D C   1 
ATOM   7926 O O   . GLN D 1 100 ? 91.283  100.534 143.254 1.00 60.33  ? 174 GLN D O   1 
ATOM   7927 C CB  . GLN D 1 100 ? 91.161  98.462  141.255 1.00 61.32  ? 174 GLN D CB  1 
ATOM   7928 C CG  . GLN D 1 100 ? 90.351  97.388  140.547 1.00 63.85  ? 174 GLN D CG  1 
ATOM   7929 C CD  . GLN D 1 100 ? 90.935  96.003  140.738 1.00 64.88  ? 174 GLN D CD  1 
ATOM   7930 O OE1 . GLN D 1 100 ? 91.992  95.841  141.346 1.00 64.18  ? 174 GLN D OE1 1 
ATOM   7931 N NE2 . GLN D 1 100 ? 90.247  94.994  140.217 1.00 63.29  ? 174 GLN D NE2 1 
ATOM   7932 N N   . ILE D 1 101 ? 91.935  101.917 141.615 1.00 48.95  ? 175 ILE D N   1 
ATOM   7933 C CA  . ILE D 1 101 ? 92.726  102.784 142.481 1.00 38.47  ? 175 ILE D CA  1 
ATOM   7934 C C   . ILE D 1 101 ? 92.191  104.204 142.369 1.00 40.60  ? 175 ILE D C   1 
ATOM   7935 O O   . ILE D 1 101 ? 91.968  104.703 141.260 1.00 49.73  ? 175 ILE D O   1 
ATOM   7936 C CB  . ILE D 1 101 ? 94.221  102.733 142.115 1.00 39.15  ? 175 ILE D CB  1 
ATOM   7937 C CG1 . ILE D 1 101 ? 94.749  101.303 142.234 1.00 43.28  ? 175 ILE D CG1 1 
ATOM   7938 C CG2 . ILE D 1 101 ? 95.022  103.672 143.002 1.00 47.19  ? 175 ILE D CG2 1 
ATOM   7939 C CD1 . ILE D 1 101 ? 94.644  100.729 143.628 1.00 46.87  ? 175 ILE D CD1 1 
ATOM   7940 N N   . ASP D 1 102 ? 91.993  104.855 143.516 1.00 29.44  ? 176 ASP D N   1 
ATOM   7941 C CA  . ASP D 1 102 ? 91.500  106.226 143.544 1.00 34.44  ? 176 ASP D CA  1 
ATOM   7942 C C   . ASP D 1 102 ? 92.627  107.251 143.466 1.00 43.10  ? 176 ASP D C   1 
ATOM   7943 O O   . ASP D 1 102 ? 92.504  108.245 142.743 1.00 50.61  ? 176 ASP D O   1 
ATOM   7944 C CB  . ASP D 1 102 ? 90.671  106.462 144.808 1.00 43.30  ? 176 ASP D CB  1 
ATOM   7945 C CG  . ASP D 1 102 ? 89.337  105.746 144.770 1.00 53.37  ? 176 ASP D CG  1 
ATOM   7946 O OD1 . ASP D 1 102 ? 88.876  105.404 143.661 1.00 55.40  ? 176 ASP D OD1 1 
ATOM   7947 O OD2 . ASP D 1 102 ? 88.749  105.520 145.848 1.00 52.48  ? 176 ASP D OD2 1 
ATOM   7948 N N   . PHE D 1 103 ? 93.715  107.039 144.204 1.00 31.89  ? 177 PHE D N   1 
ATOM   7949 C CA  . PHE D 1 103 ? 94.892  107.890 144.088 1.00 25.67  ? 177 PHE D CA  1 
ATOM   7950 C C   . PHE D 1 103 ? 96.104  107.119 144.591 1.00 28.37  ? 177 PHE D C   1 
ATOM   7951 O O   . PHE D 1 103 ? 95.976  106.111 145.288 1.00 39.94  ? 177 PHE D O   1 
ATOM   7952 C CB  . PHE D 1 103 ? 94.714  109.218 144.837 1.00 31.54  ? 177 PHE D CB  1 
ATOM   7953 C CG  . PHE D 1 103 ? 95.042  109.153 146.300 1.00 23.41  ? 177 PHE D CG  1 
ATOM   7954 C CD1 . PHE D 1 103 ? 94.147  108.603 147.199 1.00 28.93  ? 177 PHE D CD1 1 
ATOM   7955 C CD2 . PHE D 1 103 ? 96.229  109.677 146.780 1.00 28.22  ? 177 PHE D CD2 1 
ATOM   7956 C CE1 . PHE D 1 103 ? 94.440  108.555 148.545 1.00 26.54  ? 177 PHE D CE1 1 
ATOM   7957 C CE2 . PHE D 1 103 ? 96.527  109.632 148.126 1.00 33.12  ? 177 PHE D CE2 1 
ATOM   7958 C CZ  . PHE D 1 103 ? 95.631  109.069 149.009 1.00 32.53  ? 177 PHE D CZ  1 
ATOM   7959 N N   . ILE D 1 104 ? 97.285  107.607 144.216 1.00 27.69  ? 178 ILE D N   1 
ATOM   7960 C CA  . ILE D 1 104 ? 98.540  106.887 144.399 1.00 19.71  ? 178 ILE D CA  1 
ATOM   7961 C C   . ILE D 1 104 ? 99.460  107.697 145.301 1.00 28.75  ? 178 ILE D C   1 
ATOM   7962 O O   . ILE D 1 104 ? 99.545  108.924 145.177 1.00 41.00  ? 178 ILE D O   1 
ATOM   7963 C CB  . ILE D 1 104 ? 99.222  106.606 143.044 1.00 21.82  ? 178 ILE D CB  1 
ATOM   7964 C CG1 . ILE D 1 104 ? 98.308  105.773 142.150 1.00 27.52  ? 178 ILE D CG1 1 
ATOM   7965 C CG2 . ILE D 1 104 ? 100.549 105.893 143.240 1.00 29.62  ? 178 ILE D CG2 1 
ATOM   7966 C CD1 . ILE D 1 104 ? 98.813  105.647 140.739 1.00 29.04  ? 178 ILE D CD1 1 
ATOM   7967 N N   . ILE D 1 105 ? 100.144 107.008 146.211 1.00 19.07  ? 179 ILE D N   1 
ATOM   7968 C CA  . ILE D 1 105 ? 101.219 107.585 147.009 1.00 16.40  ? 179 ILE D CA  1 
ATOM   7969 C C   . ILE D 1 105 ? 102.512 106.894 146.601 1.00 26.73  ? 179 ILE D C   1 
ATOM   7970 O O   . ILE D 1 105 ? 102.608 105.662 146.651 1.00 37.03  ? 179 ILE D O   1 
ATOM   7971 C CB  . ILE D 1 105 ? 100.960 107.431 148.515 1.00 14.37  ? 179 ILE D CB  1 
ATOM   7972 C CG1 . ILE D 1 105 ? 99.538  107.871 148.860 1.00 19.82  ? 179 ILE D CG1 1 
ATOM   7973 C CG2 . ILE D 1 105 ? 101.975 108.229 149.312 1.00 27.07  ? 179 ILE D CG2 1 
ATOM   7974 C CD1 . ILE D 1 105 ? 99.231  107.833 150.337 1.00 23.42  ? 179 ILE D CD1 1 
ATOM   7975 N N   . CYS D 1 106 ? 103.505 107.681 146.197 1.00 33.94  ? 180 CYS D N   1 
ATOM   7976 C CA  . CYS D 1 106 ? 104.768 107.162 145.690 1.00 29.76  ? 180 CYS D CA  1 
ATOM   7977 C C   . CYS D 1 106 ? 105.887 107.482 146.670 1.00 38.81  ? 180 CYS D C   1 
ATOM   7978 O O   . CYS D 1 106 ? 105.971 108.605 147.179 1.00 39.91  ? 180 CYS D O   1 
ATOM   7979 C CB  . CYS D 1 106 ? 105.088 107.748 144.314 1.00 30.03  ? 180 CYS D CB  1 
ATOM   7980 S SG  . CYS D 1 106 ? 104.178 106.987 142.951 1.00 53.90  ? 180 CYS D SG  1 
ATOM   7981 N N   . LEU D 1 107 ? 106.741 106.496 146.931 1.00 30.53  ? 181 LEU D N   1 
ATOM   7982 C CA  . LEU D 1 107 ? 107.859 106.634 147.854 1.00 20.32  ? 181 LEU D CA  1 
ATOM   7983 C C   . LEU D 1 107 ? 109.158 106.319 147.127 1.00 27.39  ? 181 LEU D C   1 
ATOM   7984 O O   . LEU D 1 107 ? 109.278 105.263 146.498 1.00 40.86  ? 181 LEU D O   1 
ATOM   7985 C CB  . LEU D 1 107 ? 107.696 105.696 149.053 1.00 24.29  ? 181 LEU D CB  1 
ATOM   7986 C CG  . LEU D 1 107 ? 106.443 105.833 149.918 1.00 24.99  ? 181 LEU D CG  1 
ATOM   7987 C CD1 . LEU D 1 107 ? 106.329 104.657 150.870 1.00 31.21  ? 181 LEU D CD1 1 
ATOM   7988 C CD2 . LEU D 1 107 ? 106.449 107.140 150.686 1.00 35.30  ? 181 LEU D CD2 1 
ATOM   7989 N N   . GLY D 1 108 ? 110.126 107.229 147.214 1.00 32.65  ? 182 GLY D N   1 
ATOM   7990 C CA  . GLY D 1 108 ? 111.473 106.914 146.778 1.00 40.92  ? 182 GLY D CA  1 
ATOM   7991 C C   . GLY D 1 108 ? 112.161 107.893 145.849 1.00 39.53  ? 182 GLY D C   1 
ATOM   7992 O O   . GLY D 1 108 ? 113.360 108.144 146.007 1.00 50.29  ? 182 GLY D O   1 
ATOM   7993 N N   . GLY D 1 109 ? 111.446 108.455 144.891 1.00 30.08  ? 183 GLY D N   1 
ATOM   7994 C CA  . GLY D 1 109 ? 112.050 109.382 143.959 1.00 36.46  ? 183 GLY D CA  1 
ATOM   7995 C C   . GLY D 1 109 ? 111.315 109.387 142.634 1.00 40.94  ? 183 GLY D C   1 
ATOM   7996 O O   . GLY D 1 109 ? 110.222 108.843 142.503 1.00 48.61  ? 183 GLY D O   1 
ATOM   7997 N N   . ASP D 1 110 ? 111.952 110.026 141.650 1.00 29.76  ? 184 ASP D N   1 
ATOM   7998 C CA  . ASP D 1 110 ? 111.335 110.197 140.339 1.00 31.57  ? 184 ASP D CA  1 
ATOM   7999 C C   . ASP D 1 110 ? 111.126 108.861 139.637 1.00 34.59  ? 184 ASP D C   1 
ATOM   8000 O O   . ASP D 1 110 ? 110.095 108.652 138.986 1.00 42.95  ? 184 ASP D O   1 
ATOM   8001 C CB  . ASP D 1 110 ? 112.191 111.125 139.478 1.00 39.04  ? 184 ASP D CB  1 
ATOM   8002 C CG  . ASP D 1 110 ? 112.362 112.497 140.097 1.00 43.32  ? 184 ASP D CG  1 
ATOM   8003 O OD1 . ASP D 1 110 ? 111.368 113.046 140.614 1.00 44.95  ? 184 ASP D OD1 1 
ATOM   8004 O OD2 . ASP D 1 110 ? 113.492 113.027 140.067 1.00 45.02  ? 184 ASP D OD2 1 
ATOM   8005 N N   . GLY D 1 111 ? 112.092 107.946 139.756 1.00 33.65  ? 185 GLY D N   1 
ATOM   8006 C CA  . GLY D 1 111 ? 111.974 106.661 139.088 1.00 32.23  ? 185 GLY D CA  1 
ATOM   8007 C C   . GLY D 1 111 ? 110.753 105.874 139.515 1.00 30.18  ? 185 GLY D C   1 
ATOM   8008 O O   . GLY D 1 111 ? 110.233 105.062 138.746 1.00 36.85  ? 185 GLY D O   1 
ATOM   8009 N N   . THR D 1 112 ? 110.282 106.095 140.743 1.00 29.28  ? 186 THR D N   1 
ATOM   8010 C CA  . THR D 1 112 ? 109.029 105.487 141.177 1.00 26.81  ? 186 THR D CA  1 
ATOM   8011 C C   . THR D 1 112 ? 107.856 106.027 140.368 1.00 36.18  ? 186 THR D C   1 
ATOM   8012 O O   . THR D 1 112 ? 107.029 105.259 139.861 1.00 44.95  ? 186 THR D O   1 
ATOM   8013 C CB  . THR D 1 112 ? 108.815 105.738 142.670 1.00 34.33  ? 186 THR D CB  1 
ATOM   8014 O OG1 . THR D 1 112 ? 109.892 105.155 143.415 1.00 38.19  ? 186 THR D OG1 1 
ATOM   8015 C CG2 . THR D 1 112 ? 107.499 105.141 143.131 1.00 38.41  ? 186 THR D CG2 1 
ATOM   8016 N N   . LEU D 1 113 ? 107.792 107.352 140.208 1.00 35.59  ? 187 LEU D N   1 
ATOM   8017 C CA  . LEU D 1 113 ? 106.678 107.964 139.492 1.00 31.41  ? 187 LEU D CA  1 
ATOM   8018 C C   . LEU D 1 113 ? 106.595 107.451 138.063 1.00 33.02  ? 187 LEU D C   1 
ATOM   8019 O O   . LEU D 1 113 ? 105.503 107.151 137.565 1.00 40.72  ? 187 LEU D O   1 
ATOM   8020 C CB  . LEU D 1 113 ? 106.820 109.484 139.505 1.00 28.46  ? 187 LEU D CB  1 
ATOM   8021 C CG  . LEU D 1 113 ? 105.542 110.239 139.155 1.00 35.40  ? 187 LEU D CG  1 
ATOM   8022 C CD1 . LEU D 1 113 ? 104.466 109.878 140.153 1.00 39.70  ? 187 LEU D CD1 1 
ATOM   8023 C CD2 . LEU D 1 113 ? 105.780 111.737 139.136 1.00 37.65  ? 187 LEU D CD2 1 
ATOM   8024 N N   . LEU D 1 114 ? 107.743 107.335 137.394 1.00 35.94  ? 188 LEU D N   1 
ATOM   8025 C CA  . LEU D 1 114 ? 107.775 106.748 136.060 1.00 35.93  ? 188 LEU D CA  1 
ATOM   8026 C C   . LEU D 1 114 ? 107.161 105.355 136.073 1.00 32.41  ? 188 LEU D C   1 
ATOM   8027 O O   . LEU D 1 114 ? 106.329 105.021 135.220 1.00 40.79  ? 188 LEU D O   1 
ATOM   8028 C CB  . LEU D 1 114 ? 109.216 106.698 135.553 1.00 36.06  ? 188 LEU D CB  1 
ATOM   8029 C CG  . LEU D 1 114 ? 109.728 107.886 134.738 1.00 30.94  ? 188 LEU D CG  1 
ATOM   8030 C CD1 . LEU D 1 114 ? 109.522 109.188 135.491 1.00 34.89  ? 188 LEU D CD1 1 
ATOM   8031 C CD2 . LEU D 1 114 ? 111.195 107.690 134.402 1.00 35.68  ? 188 LEU D CD2 1 
ATOM   8032 N N   . TYR D 1 115 ? 107.539 104.539 137.059 1.00 30.99  ? 189 TYR D N   1 
ATOM   8033 C CA  . TYR D 1 115 ? 106.950 103.211 137.185 1.00 28.20  ? 189 TYR D CA  1 
ATOM   8034 C C   . TYR D 1 115 ? 105.449 103.307 137.417 1.00 33.31  ? 189 TYR D C   1 
ATOM   8035 O O   . TYR D 1 115 ? 104.681 102.475 136.918 1.00 39.53  ? 189 TYR D O   1 
ATOM   8036 C CB  . TYR D 1 115 ? 107.635 102.445 138.317 1.00 32.74  ? 189 TYR D CB  1 
ATOM   8037 C CG  . TYR D 1 115 ? 107.025 101.097 138.623 1.00 32.44  ? 189 TYR D CG  1 
ATOM   8038 C CD1 . TYR D 1 115 ? 107.313 99.990  137.837 1.00 38.26  ? 189 TYR D CD1 1 
ATOM   8039 C CD2 . TYR D 1 115 ? 106.176 100.927 139.707 1.00 36.91  ? 189 TYR D CD2 1 
ATOM   8040 C CE1 . TYR D 1 115 ? 106.763 98.755  138.114 1.00 38.01  ? 189 TYR D CE1 1 
ATOM   8041 C CE2 . TYR D 1 115 ? 105.623 99.695  139.993 1.00 40.44  ? 189 TYR D CE2 1 
ATOM   8042 C CZ  . TYR D 1 115 ? 105.919 98.614  139.193 1.00 39.98  ? 189 TYR D CZ  1 
ATOM   8043 O OH  . TYR D 1 115 ? 105.370 97.385  139.475 1.00 45.60  ? 189 TYR D OH  1 
ATOM   8044 N N   . ALA D 1 116 ? 105.010 104.330 138.156 1.00 37.57  ? 190 ALA D N   1 
ATOM   8045 C CA  . ALA D 1 116 ? 103.580 104.544 138.346 1.00 34.12  ? 190 ALA D CA  1 
ATOM   8046 C C   . ALA D 1 116 ? 102.875 104.793 137.021 1.00 38.12  ? 190 ALA D C   1 
ATOM   8047 O O   . ALA D 1 116 ? 101.714 104.405 136.854 1.00 46.86  ? 190 ALA D O   1 
ATOM   8048 C CB  . ALA D 1 116 ? 103.344 105.711 139.304 1.00 38.03  ? 190 ALA D CB  1 
ATOM   8049 N N   . SER D 1 117 ? 103.555 105.437 136.069 1.00 34.61  ? 191 SER D N   1 
ATOM   8050 C CA  . SER D 1 117 ? 102.969 105.624 134.749 1.00 33.27  ? 191 SER D CA  1 
ATOM   8051 C C   . SER D 1 117 ? 102.992 104.344 133.926 1.00 37.87  ? 191 SER D C   1 
ATOM   8052 O O   . SER D 1 117 ? 102.209 104.216 132.979 1.00 40.84  ? 191 SER D O   1 
ATOM   8053 C CB  . SER D 1 117 ? 103.698 106.739 134.000 1.00 38.05  ? 191 SER D CB  1 
ATOM   8054 O OG  . SER D 1 117 ? 103.513 106.619 132.601 1.00 46.39  ? 191 SER D OG  1 
ATOM   8055 N N   . SER D 1 118 ? 103.870 103.396 134.265 1.00 37.68  ? 192 SER D N   1 
ATOM   8056 C CA  . SER D 1 118 ? 103.939 102.151 133.506 1.00 31.64  ? 192 SER D CA  1 
ATOM   8057 C C   . SER D 1 118 ? 102.735 101.261 133.789 1.00 36.70  ? 192 SER D C   1 
ATOM   8058 O O   . SER D 1 118 ? 102.230 100.586 132.885 1.00 40.62  ? 192 SER D O   1 
ATOM   8059 C CB  . SER D 1 118 ? 105.239 101.414 133.824 1.00 39.01  ? 192 SER D CB  1 
ATOM   8060 O OG  . SER D 1 118 ? 106.365 102.167 133.411 1.00 43.91  ? 192 SER D OG  1 
ATOM   8061 N N   . LEU D 1 119 ? 102.264 101.243 135.037 1.00 40.65  ? 193 LEU D N   1 
ATOM   8062 C CA  . LEU D 1 119 ? 101.150 100.382 135.411 1.00 38.32  ? 193 LEU D CA  1 
ATOM   8063 C C   . LEU D 1 119 ? 99.814  100.870 134.871 1.00 41.42  ? 193 LEU D C   1 
ATOM   8064 O O   . LEU D 1 119 ? 98.849  100.098 134.869 1.00 45.94  ? 193 LEU D O   1 
ATOM   8065 C CB  . LEU D 1 119 ? 101.066 100.263 136.933 1.00 40.54  ? 193 LEU D CB  1 
ATOM   8066 C CG  . LEU D 1 119 ? 102.355 99.918  137.679 1.00 40.19  ? 193 LEU D CG  1 
ATOM   8067 C CD1 . LEU D 1 119 ? 102.274 100.400 139.117 1.00 42.98  ? 193 LEU D CD1 1 
ATOM   8068 C CD2 . LEU D 1 119 ? 102.619 98.425  137.625 1.00 43.64  ? 193 LEU D CD2 1 
ATOM   8069 N N   . PHE D 1 120 ? 99.730  102.120 134.416 1.00 42.21  ? 194 PHE D N   1 
ATOM   8070 C CA  . PHE D 1 120 ? 98.473  102.726 133.974 1.00 41.21  ? 194 PHE D CA  1 
ATOM   8071 C C   . PHE D 1 120 ? 98.664  103.246 132.553 1.00 41.77  ? 194 PHE D C   1 
ATOM   8072 O O   . PHE D 1 120 ? 99.058  104.398 132.351 1.00 46.16  ? 194 PHE D O   1 
ATOM   8073 C CB  . PHE D 1 120 ? 98.046  103.830 134.933 1.00 38.84  ? 194 PHE D CB  1 
ATOM   8074 C CG  . PHE D 1 120 ? 97.705  103.335 136.307 1.00 39.83  ? 194 PHE D CG  1 
ATOM   8075 C CD1 . PHE D 1 120 ? 96.493  102.714 136.554 1.00 43.82  ? 194 PHE D CD1 1 
ATOM   8076 C CD2 . PHE D 1 120 ? 98.606  103.468 137.347 1.00 42.76  ? 194 PHE D CD2 1 
ATOM   8077 C CE1 . PHE D 1 120 ? 96.181  102.253 137.817 1.00 45.78  ? 194 PHE D CE1 1 
ATOM   8078 C CE2 . PHE D 1 120 ? 98.300  103.003 138.609 1.00 41.98  ? 194 PHE D CE2 1 
ATOM   8079 C CZ  . PHE D 1 120 ? 97.086  102.397 138.845 1.00 44.75  ? 194 PHE D CZ  1 
ATOM   8080 N N   . GLN D 1 121 ? 98.383  102.392 131.569 1.00 35.83  ? 195 GLN D N   1 
ATOM   8081 C CA  . GLN D 1 121 ? 98.470  102.790 130.172 1.00 37.48  ? 195 GLN D CA  1 
ATOM   8082 C C   . GLN D 1 121 ? 97.245  103.562 129.704 1.00 40.81  ? 195 GLN D C   1 
ATOM   8083 O O   . GLN D 1 121 ? 97.255  104.090 128.587 1.00 45.44  ? 195 GLN D O   1 
ATOM   8084 C CB  . GLN D 1 121 ? 98.678  101.557 129.285 1.00 36.71  ? 195 GLN D CB  1 
ATOM   8085 C CG  . GLN D 1 121 ? 99.909  100.684 129.604 1.00 40.41  ? 195 GLN D CG  1 
ATOM   8086 C CD  . GLN D 1 121 ? 101.256 101.417 129.617 1.00 40.51  ? 195 GLN D CD  1 
ATOM   8087 O OE1 . GLN D 1 121 ? 101.333 102.645 129.596 1.00 38.75  ? 195 GLN D OE1 1 
ATOM   8088 N NE2 . GLN D 1 121 ? 102.332 100.640 129.654 1.00 41.58  ? 195 GLN D NE2 1 
ATOM   8089 N N   . GLY D 1 122 ? 96.202  103.639 130.524 1.00 36.68  ? 196 GLY D N   1 
ATOM   8090 C CA  . GLY D 1 122 ? 95.038  104.444 130.217 1.00 28.17  ? 196 GLY D CA  1 
ATOM   8091 C C   . GLY D 1 122 ? 94.909  105.614 131.168 1.00 34.27  ? 196 GLY D C   1 
ATOM   8092 O O   . GLY D 1 122 ? 95.899  106.292 131.459 1.00 42.40  ? 196 GLY D O   1 
ATOM   8093 N N   . SER D 1 123 ? 93.700  105.866 131.658 1.00 33.16  ? 197 SER D N   1 
ATOM   8094 C CA  . SER D 1 123 ? 93.505  106.920 132.642 1.00 30.67  ? 197 SER D CA  1 
ATOM   8095 C C   . SER D 1 123 ? 94.175  106.539 133.956 1.00 38.20  ? 197 SER D C   1 
ATOM   8096 O O   . SER D 1 123 ? 94.073  105.399 134.417 1.00 47.00  ? 197 SER D O   1 
ATOM   8097 C CB  . SER D 1 123 ? 92.016  107.180 132.860 1.00 37.50  ? 197 SER D CB  1 
ATOM   8098 O OG  . SER D 1 123 ? 91.813  108.191 133.832 1.00 40.89  ? 197 SER D OG  1 
ATOM   8099 N N   . VAL D 1 124 ? 94.863  107.502 134.561 1.00 38.73  ? 198 VAL D N   1 
ATOM   8100 C CA  . VAL D 1 124 ? 95.661  107.246 135.757 1.00 38.99  ? 198 VAL D CA  1 
ATOM   8101 C C   . VAL D 1 124 ? 95.152  108.108 136.908 1.00 36.55  ? 198 VAL D C   1 
ATOM   8102 O O   . VAL D 1 124 ? 94.843  109.292 136.710 1.00 37.54  ? 198 VAL D O   1 
ATOM   8103 C CB  . VAL D 1 124 ? 97.156  107.481 135.475 1.00 35.74  ? 198 VAL D CB  1 
ATOM   8104 C CG1 . VAL D 1 124 ? 97.409  108.916 135.066 1.00 30.28  ? 198 VAL D CG1 1 
ATOM   8105 C CG2 . VAL D 1 124 ? 98.004  107.109 136.683 1.00 39.90  ? 198 VAL D CG2 1 
ATOM   8106 N N   . PRO D 1 125 ? 95.019  107.556 138.110 1.00 31.68  ? 199 PRO D N   1 
ATOM   8107 C CA  . PRO D 1 125 ? 94.579  108.355 139.255 1.00 30.13  ? 199 PRO D CA  1 
ATOM   8108 C C   . PRO D 1 125 ? 95.654  109.337 139.683 1.00 38.33  ? 199 PRO D C   1 
ATOM   8109 O O   . PRO D 1 125 ? 96.834  109.164 139.343 1.00 47.48  ? 199 PRO D O   1 
ATOM   8110 C CB  . PRO D 1 125 ? 94.321  107.297 140.338 1.00 33.96  ? 199 PRO D CB  1 
ATOM   8111 C CG  . PRO D 1 125 ? 95.199  106.162 139.956 1.00 34.25  ? 199 PRO D CG  1 
ATOM   8112 C CD  . PRO D 1 125 ? 95.140  106.131 138.460 1.00 32.84  ? 199 PRO D CD  1 
ATOM   8113 N N   . PRO D 1 126 ? 95.285  110.388 140.417 1.00 18.63  ? 200 PRO D N   1 
ATOM   8114 C CA  . PRO D 1 126 ? 96.290  111.356 140.873 1.00 26.64  ? 200 PRO D CA  1 
ATOM   8115 C C   . PRO D 1 126 ? 97.324  110.705 141.778 1.00 22.78  ? 200 PRO D C   1 
ATOM   8116 O O   . PRO D 1 126 ? 97.034  109.763 142.517 1.00 35.29  ? 200 PRO D O   1 
ATOM   8117 C CB  . PRO D 1 126 ? 95.468  112.407 141.630 1.00 28.11  ? 200 PRO D CB  1 
ATOM   8118 C CG  . PRO D 1 126 ? 94.123  111.816 141.835 1.00 26.88  ? 200 PRO D CG  1 
ATOM   8119 C CD  . PRO D 1 126 ? 93.916  110.772 140.796 1.00 19.89  ? 200 PRO D CD  1 
ATOM   8120 N N   . VAL D 1 127 ? 98.547  111.220 141.707 1.00 19.15  ? 201 VAL D N   1 
ATOM   8121 C CA  . VAL D 1 127 ? 99.674  110.671 142.447 1.00 19.68  ? 201 VAL D CA  1 
ATOM   8122 C C   . VAL D 1 127 ? 100.160 111.695 143.462 1.00 27.39  ? 201 VAL D C   1 
ATOM   8123 O O   . VAL D 1 127 ? 100.034 112.908 143.267 1.00 32.29  ? 201 VAL D O   1 
ATOM   8124 C CB  . VAL D 1 127 ? 100.819 110.245 141.504 1.00 18.11  ? 201 VAL D CB  1 
ATOM   8125 C CG1 . VAL D 1 127 ? 100.307 109.267 140.465 1.00 31.47  ? 201 VAL D CG1 1 
ATOM   8126 C CG2 . VAL D 1 127 ? 101.416 111.460 140.828 1.00 32.17  ? 201 VAL D CG2 1 
ATOM   8127 N N   . MET D 1 128 ? 100.715 111.190 144.565 1.00 28.48  ? 202 MET D N   1 
ATOM   8128 C CA  . MET D 1 128 ? 101.264 112.012 145.644 1.00 18.33  ? 202 MET D CA  1 
ATOM   8129 C C   . MET D 1 128 ? 102.672 111.496 145.925 1.00 28.44  ? 202 MET D C   1 
ATOM   8130 O O   . MET D 1 128 ? 102.867 110.625 146.777 1.00 39.68  ? 202 MET D O   1 
ATOM   8131 C CB  . MET D 1 128 ? 100.377 111.956 146.884 1.00 17.12  ? 202 MET D CB  1 
ATOM   8132 C CG  . MET D 1 128 ? 100.808 112.881 148.008 1.00 22.83  ? 202 MET D CG  1 
ATOM   8133 S SD  . MET D 1 128 ? 99.649  112.868 149.388 1.00 25.73  ? 202 MET D SD  1 
ATOM   8134 C CE  . MET D 1 128 ? 100.497 113.927 150.554 1.00 28.91  ? 202 MET D CE  1 
ATOM   8135 N N   . ALA D 1 129 ? 103.652 112.035 145.205 1.00 20.71  ? 203 ALA D N   1 
ATOM   8136 C CA  . ALA D 1 129 ? 105.024 111.563 145.316 1.00 18.14  ? 203 ALA D CA  1 
ATOM   8137 C C   . ALA D 1 129 ? 105.674 112.074 146.594 1.00 26.80  ? 203 ALA D C   1 
ATOM   8138 O O   . ALA D 1 129 ? 105.546 113.249 146.948 1.00 34.64  ? 203 ALA D O   1 
ATOM   8139 C CB  . ALA D 1 129 ? 105.839 112.005 144.102 1.00 30.22  ? 203 ALA D CB  1 
ATOM   8140 N N   . PHE D 1 130 ? 106.381 111.181 147.281 1.00 31.64  ? 204 PHE D N   1 
ATOM   8141 C CA  . PHE D 1 130 ? 107.100 111.501 148.506 1.00 15.18  ? 204 PHE D CA  1 
ATOM   8142 C C   . PHE D 1 130 ? 108.588 111.285 148.277 1.00 22.13  ? 204 PHE D C   1 
ATOM   8143 O O   . PHE D 1 130 ? 108.993 110.239 147.762 1.00 36.48  ? 204 PHE D O   1 
ATOM   8144 C CB  . PHE D 1 130 ? 106.619 110.633 149.671 1.00 20.62  ? 204 PHE D CB  1 
ATOM   8145 C CG  . PHE D 1 130 ? 105.528 111.258 150.490 1.00 20.74  ? 204 PHE D CG  1 
ATOM   8146 C CD1 . PHE D 1 130 ? 105.791 112.339 151.312 1.00 26.14  ? 204 PHE D CD1 1 
ATOM   8147 C CD2 . PHE D 1 130 ? 104.239 110.761 150.441 1.00 20.49  ? 204 PHE D CD2 1 
ATOM   8148 C CE1 . PHE D 1 130 ? 104.787 112.912 152.067 1.00 27.62  ? 204 PHE D CE1 1 
ATOM   8149 C CE2 . PHE D 1 130 ? 103.232 111.330 151.193 1.00 17.32  ? 204 PHE D CE2 1 
ATOM   8150 C CZ  . PHE D 1 130 ? 103.506 112.406 152.006 1.00 18.62  ? 204 PHE D CZ  1 
ATOM   8151 N N   . HIS D 1 131 ? 109.397 112.270 148.656 1.00 29.98  ? 205 HIS D N   1 
ATOM   8152 C CA  . HIS D 1 131 ? 110.847 112.163 148.564 1.00 25.25  ? 205 HIS D CA  1 
ATOM   8153 C C   . HIS D 1 131 ? 111.416 111.811 149.931 1.00 40.52  ? 205 HIS D C   1 
ATOM   8154 O O   . HIS D 1 131 ? 111.141 112.496 150.922 1.00 45.15  ? 205 HIS D O   1 
ATOM   8155 C CB  . HIS D 1 131 ? 111.470 113.457 148.033 1.00 23.90  ? 205 HIS D CB  1 
ATOM   8156 C CG  . HIS D 1 131 ? 111.334 114.628 148.955 1.00 24.81  ? 205 HIS D CG  1 
ATOM   8157 N ND1 . HIS D 1 131 ? 112.153 114.816 150.048 1.00 32.17  ? 205 HIS D ND1 1 
ATOM   8158 C CD2 . HIS D 1 131 ? 110.483 115.681 148.939 1.00 33.46  ? 205 HIS D CD2 1 
ATOM   8159 C CE1 . HIS D 1 131 ? 111.806 115.928 150.670 1.00 31.82  ? 205 HIS D CE1 1 
ATOM   8160 N NE2 . HIS D 1 131 ? 110.795 116.472 150.017 1.00 35.30  ? 205 HIS D NE2 1 
ATOM   8161 N N   . LEU D 1 132 ? 112.191 110.729 149.983 1.00 34.91  ? 206 LEU D N   1 
ATOM   8162 C CA  . LEU D 1 132 ? 112.799 110.239 151.219 1.00 33.39  ? 206 LEU D CA  1 
ATOM   8163 C C   . LEU D 1 132 ? 114.279 110.015 150.930 1.00 44.75  ? 206 LEU D C   1 
ATOM   8164 O O   . LEU D 1 132 ? 114.687 108.922 150.529 1.00 46.65  ? 206 LEU D O   1 
ATOM   8165 C CB  . LEU D 1 132 ? 112.110 108.970 151.702 1.00 34.10  ? 206 LEU D CB  1 
ATOM   8166 C CG  . LEU D 1 132 ? 110.610 109.124 151.950 1.00 34.58  ? 206 LEU D CG  1 
ATOM   8167 C CD1 . LEU D 1 132 ? 109.814 108.524 150.803 1.00 41.54  ? 206 LEU D CD1 1 
ATOM   8168 C CD2 . LEU D 1 132 ? 110.211 108.508 153.271 1.00 37.92  ? 206 LEU D CD2 1 
ATOM   8169 N N   . GLY D 1 133 ? 115.079 111.053 151.135 1.00 54.31  ? 207 GLY D N   1 
ATOM   8170 C CA  . GLY D 1 133 ? 116.480 111.019 150.780 1.00 53.72  ? 207 GLY D CA  1 
ATOM   8171 C C   . GLY D 1 133 ? 116.727 111.528 149.371 1.00 58.55  ? 207 GLY D C   1 
ATOM   8172 O O   . GLY D 1 133 ? 115.870 111.460 148.490 1.00 58.07  ? 207 GLY D O   1 
ATOM   8173 N N   . SER D 1 134 ? 117.938 112.051 149.168 1.00 69.94  ? 208 SER D N   1 
ATOM   8174 C CA  . SER D 1 134 ? 118.337 112.654 147.900 1.00 69.39  ? 208 SER D CA  1 
ATOM   8175 C C   . SER D 1 134 ? 117.373 113.763 147.495 1.00 66.47  ? 208 SER D C   1 
ATOM   8176 O O   . SER D 1 134 ? 116.713 114.363 148.350 1.00 66.00  ? 208 SER D O   1 
ATOM   8177 C CB  . SER D 1 134 ? 118.426 111.592 146.799 1.00 67.08  ? 208 SER D CB  1 
ATOM   8178 O OG  . SER D 1 134 ? 118.895 112.153 145.585 1.00 68.14  ? 208 SER D OG  1 
ATOM   8179 N N   . LEU D 1 135 ? 117.287 114.046 146.198 1.00 60.21  ? 209 LEU D N   1 
ATOM   8180 C CA  . LEU D 1 135 ? 116.406 115.086 145.690 1.00 57.58  ? 209 LEU D CA  1 
ATOM   8181 C C   . LEU D 1 135 ? 115.655 114.567 144.474 1.00 57.96  ? 209 LEU D C   1 
ATOM   8182 O O   . LEU D 1 135 ? 116.217 113.841 143.650 1.00 57.49  ? 209 LEU D O   1 
ATOM   8183 C CB  . LEU D 1 135 ? 117.188 116.354 145.321 1.00 59.64  ? 209 LEU D CB  1 
ATOM   8184 C CG  . LEU D 1 135 ? 117.821 117.122 146.482 1.00 61.50  ? 209 LEU D CG  1 
ATOM   8185 C CD1 . LEU D 1 135 ? 118.692 118.258 145.966 1.00 59.87  ? 209 LEU D CD1 1 
ATOM   8186 C CD2 . LEU D 1 135 ? 116.749 117.648 147.424 1.00 58.54  ? 209 LEU D CD2 1 
ATOM   8187 N N   . GLY D 1 136 ? 114.383 114.943 144.371 1.00 43.88  ? 210 GLY D N   1 
ATOM   8188 C CA  . GLY D 1 136 ? 113.567 114.549 143.241 1.00 38.89  ? 210 GLY D CA  1 
ATOM   8189 C C   . GLY D 1 136 ? 112.886 115.725 142.574 1.00 39.58  ? 210 GLY D C   1 
ATOM   8190 O O   . GLY D 1 136 ? 112.327 116.593 143.251 1.00 46.43  ? 210 GLY D O   1 
ATOM   8191 N N   . PHE D 1 137 ? 112.927 115.764 141.241 1.00 35.23  ? 211 PHE D N   1 
ATOM   8192 C CA  . PHE D 1 137 ? 112.303 116.865 140.517 1.00 33.38  ? 211 PHE D CA  1 
ATOM   8193 C C   . PHE D 1 137 ? 110.784 116.734 140.503 1.00 42.11  ? 211 PHE D C   1 
ATOM   8194 O O   . PHE D 1 137 ? 110.076 117.747 140.479 1.00 44.36  ? 211 PHE D O   1 
ATOM   8195 C CB  . PHE D 1 137 ? 112.850 116.923 139.090 1.00 35.54  ? 211 PHE D CB  1 
ATOM   8196 C CG  . PHE D 1 137 ? 112.302 118.055 138.272 1.00 37.54  ? 211 PHE D CG  1 
ATOM   8197 C CD1 . PHE D 1 137 ? 112.749 119.348 138.472 1.00 32.38  ? 211 PHE D CD1 1 
ATOM   8198 C CD2 . PHE D 1 137 ? 111.337 117.828 137.307 1.00 46.35  ? 211 PHE D CD2 1 
ATOM   8199 C CE1 . PHE D 1 137 ? 112.247 120.395 137.726 1.00 36.06  ? 211 PHE D CE1 1 
ATOM   8200 C CE2 . PHE D 1 137 ? 110.828 118.871 136.557 1.00 46.29  ? 211 PHE D CE2 1 
ATOM   8201 C CZ  . PHE D 1 137 ? 111.286 120.156 136.766 1.00 43.80  ? 211 PHE D CZ  1 
ATOM   8202 N N   . LEU D 1 138 ? 110.269 115.505 140.519 1.00 38.30  ? 212 LEU D N   1 
ATOM   8203 C CA  . LEU D 1 138 ? 108.837 115.239 140.490 1.00 32.26  ? 212 LEU D CA  1 
ATOM   8204 C C   . LEU D 1 138 ? 108.283 114.812 141.845 1.00 39.13  ? 212 LEU D C   1 
ATOM   8205 O O   . LEU D 1 138 ? 107.133 114.367 141.917 1.00 44.48  ? 212 LEU D O   1 
ATOM   8206 C CB  . LEU D 1 138 ? 108.522 114.167 139.444 1.00 34.05  ? 212 LEU D CB  1 
ATOM   8207 C CG  . LEU D 1 138 ? 109.102 114.354 138.043 1.00 30.19  ? 212 LEU D CG  1 
ATOM   8208 C CD1 . LEU D 1 138 ? 108.724 113.187 137.150 1.00 35.54  ? 212 LEU D CD1 1 
ATOM   8209 C CD2 . LEU D 1 138 ? 108.610 115.658 137.444 1.00 38.75  ? 212 LEU D CD2 1 
ATOM   8210 N N   . THR D 1 139 ? 109.067 114.936 142.916 1.00 40.49  ? 213 THR D N   1 
ATOM   8211 C CA  . THR D 1 139 ? 108.676 114.492 144.255 1.00 33.26  ? 213 THR D CA  1 
ATOM   8212 C C   . THR D 1 139 ? 108.709 115.684 145.202 1.00 32.87  ? 213 THR D C   1 
ATOM   8213 O O   . THR D 1 139 ? 109.740 115.958 145.837 1.00 42.13  ? 213 THR D O   1 
ATOM   8214 C CB  . THR D 1 139 ? 109.592 113.375 144.749 1.00 36.11  ? 213 THR D CB  1 
ATOM   8215 O OG1 . THR D 1 139 ? 110.897 113.907 145.005 1.00 41.08  ? 213 THR D OG1 1 
ATOM   8216 C CG2 . THR D 1 139 ? 109.694 112.270 143.711 1.00 34.06  ? 213 THR D CG2 1 
ATOM   8217 N N   . PRO D 1 140 ? 107.603 116.422 145.331 1.00 24.16  ? 214 PRO D N   1 
ATOM   8218 C CA  . PRO D 1 140 ? 107.608 117.646 146.139 1.00 24.06  ? 214 PRO D CA  1 
ATOM   8219 C C   . PRO D 1 140 ? 107.237 117.479 147.605 1.00 27.26  ? 214 PRO D C   1 
ATOM   8220 O O   . PRO D 1 140 ? 107.414 118.437 148.371 1.00 33.58  ? 214 PRO D O   1 
ATOM   8221 C CB  . PRO D 1 140 ? 106.556 118.502 145.424 1.00 28.99  ? 214 PRO D CB  1 
ATOM   8222 C CG  . PRO D 1 140 ? 105.555 117.493 144.984 1.00 24.80  ? 214 PRO D CG  1 
ATOM   8223 C CD  . PRO D 1 140 ? 106.370 116.304 144.532 1.00 25.52  ? 214 PRO D CD  1 
ATOM   8224 N N   . PHE D 1 141 ? 106.740 116.319 148.024 1.00 27.95  ? 215 PHE D N   1 
ATOM   8225 C CA  . PHE D 1 141 ? 106.228 116.147 149.378 1.00 23.98  ? 215 PHE D CA  1 
ATOM   8226 C C   . PHE D 1 141 ? 107.303 115.579 150.295 1.00 29.12  ? 215 PHE D C   1 
ATOM   8227 O O   . PHE D 1 141 ? 107.890 114.532 150.003 1.00 35.18  ? 215 PHE D O   1 
ATOM   8228 C CB  . PHE D 1 141 ? 105.007 115.228 149.378 1.00 18.28  ? 215 PHE D CB  1 
ATOM   8229 C CG  . PHE D 1 141 ? 103.723 115.923 149.033 1.00 17.91  ? 215 PHE D CG  1 
ATOM   8230 C CD1 . PHE D 1 141 ? 102.991 116.575 150.008 1.00 30.91  ? 215 PHE D CD1 1 
ATOM   8231 C CD2 . PHE D 1 141 ? 103.245 115.917 147.735 1.00 21.54  ? 215 PHE D CD2 1 
ATOM   8232 C CE1 . PHE D 1 141 ? 101.808 117.212 149.694 1.00 28.66  ? 215 PHE D CE1 1 
ATOM   8233 C CE2 . PHE D 1 141 ? 102.063 116.552 147.416 1.00 27.76  ? 215 PHE D CE2 1 
ATOM   8234 C CZ  . PHE D 1 141 ? 101.344 117.200 148.397 1.00 23.90  ? 215 PHE D CZ  1 
ATOM   8235 N N   . SER D 1 142 ? 107.548 116.268 151.406 1.00 30.95  ? 216 SER D N   1 
ATOM   8236 C CA  . SER D 1 142 ? 108.442 115.779 152.445 1.00 32.62  ? 216 SER D CA  1 
ATOM   8237 C C   . SER D 1 142 ? 107.677 114.856 153.383 1.00 38.27  ? 216 SER D C   1 
ATOM   8238 O O   . SER D 1 142 ? 106.503 115.091 153.683 1.00 43.37  ? 216 SER D O   1 
ATOM   8239 C CB  . SER D 1 142 ? 109.049 116.942 153.230 1.00 37.76  ? 216 SER D CB  1 
ATOM   8240 O OG  . SER D 1 142 ? 108.053 117.637 153.961 1.00 40.52  ? 216 SER D OG  1 
ATOM   8241 N N   . PHE D 1 143 ? 108.350 113.800 153.847 1.00 33.40  ? 217 PHE D N   1 
ATOM   8242 C CA  . PHE D 1 143 ? 107.664 112.795 154.650 1.00 29.45  ? 217 PHE D CA  1 
ATOM   8243 C C   . PHE D 1 143 ? 107.338 113.283 156.055 1.00 27.87  ? 217 PHE D C   1 
ATOM   8244 O O   . PHE D 1 143 ? 106.498 112.674 156.726 1.00 41.24  ? 217 PHE D O   1 
ATOM   8245 C CB  . PHE D 1 143 ? 108.495 111.516 154.733 1.00 32.71  ? 217 PHE D CB  1 
ATOM   8246 C CG  . PHE D 1 143 ? 107.705 110.317 155.168 1.00 28.97  ? 217 PHE D CG  1 
ATOM   8247 C CD1 . PHE D 1 143 ? 106.776 109.741 154.319 1.00 29.78  ? 217 PHE D CD1 1 
ATOM   8248 C CD2 . PHE D 1 143 ? 107.878 109.775 156.429 1.00 32.05  ? 217 PHE D CD2 1 
ATOM   8249 C CE1 . PHE D 1 143 ? 106.042 108.643 154.716 1.00 31.74  ? 217 PHE D CE1 1 
ATOM   8250 C CE2 . PHE D 1 143 ? 107.145 108.677 156.831 1.00 33.71  ? 217 PHE D CE2 1 
ATOM   8251 C CZ  . PHE D 1 143 ? 106.226 108.110 155.973 1.00 33.80  ? 217 PHE D CZ  1 
ATOM   8252 N N   . GLU D 1 144 ? 107.978 114.351 156.520 1.00 30.04  ? 218 GLU D N   1 
ATOM   8253 C CA  . GLU D 1 144 ? 107.668 114.880 157.840 1.00 31.00  ? 218 GLU D CA  1 
ATOM   8254 C C   . GLU D 1 144 ? 106.247 115.429 157.870 1.00 25.04  ? 218 GLU D C   1 
ATOM   8255 O O   . GLU D 1 144 ? 105.801 116.095 156.932 1.00 38.22  ? 218 GLU D O   1 
ATOM   8256 C CB  . GLU D 1 144 ? 108.675 115.963 158.235 1.00 41.72  ? 218 GLU D CB  1 
ATOM   8257 C CG  . GLU D 1 144 ? 108.646 117.212 157.368 1.00 42.85  ? 218 GLU D CG  1 
ATOM   8258 C CD  . GLU D 1 144 ? 109.705 118.222 157.764 1.00 45.64  ? 218 GLU D CD  1 
ATOM   8259 O OE1 . GLU D 1 144 ? 110.481 117.937 158.701 1.00 42.22  ? 218 GLU D OE1 1 
ATOM   8260 O OE2 . GLU D 1 144 ? 109.763 119.301 157.138 1.00 44.63  ? 218 GLU D OE2 1 
ATOM   8261 N N   . ASN D 1 145 ? 105.532 115.129 158.956 1.00 29.77  ? 219 ASN D N   1 
ATOM   8262 C CA  . ASN D 1 145 ? 104.142 115.551 159.129 1.00 30.00  ? 219 ASN D CA  1 
ATOM   8263 C C   . ASN D 1 145 ? 103.276 115.093 157.958 1.00 41.56  ? 219 ASN D C   1 
ATOM   8264 O O   . ASN D 1 145 ? 102.456 115.846 157.429 1.00 46.25  ? 219 ASN D O   1 
ATOM   8265 C CB  . ASN D 1 145 ? 104.047 117.066 159.319 1.00 32.46  ? 219 ASN D CB  1 
ATOM   8266 C CG  . ASN D 1 145 ? 102.792 117.484 160.057 1.00 39.21  ? 219 ASN D CG  1 
ATOM   8267 O OD1 . ASN D 1 145 ? 101.895 116.674 160.288 1.00 43.36  ? 219 ASN D OD1 1 
ATOM   8268 N ND2 . ASN D 1 145 ? 102.722 118.755 160.431 1.00 40.72  ? 219 ASN D ND2 1 
ATOM   8269 N N   . PHE D 1 146 ? 103.462 113.836 157.548 1.00 37.91  ? 220 PHE D N   1 
ATOM   8270 C CA  . PHE D 1 146 ? 102.738 113.322 156.392 1.00 20.46  ? 220 PHE D CA  1 
ATOM   8271 C C   . PHE D 1 146 ? 101.264 113.087 156.685 1.00 27.27  ? 220 PHE D C   1 
ATOM   8272 O O   . PHE D 1 146 ? 100.462 113.043 155.746 1.00 43.58  ? 220 PHE D O   1 
ATOM   8273 C CB  . PHE D 1 146 ? 103.395 112.031 155.888 1.00 26.00  ? 220 PHE D CB  1 
ATOM   8274 C CG  . PHE D 1 146 ? 103.095 110.815 156.724 1.00 30.05  ? 220 PHE D CG  1 
ATOM   8275 C CD1 . PHE D 1 146 ? 101.994 110.018 156.451 1.00 34.19  ? 220 PHE D CD1 1 
ATOM   8276 C CD2 . PHE D 1 146 ? 103.924 110.460 157.773 1.00 34.78  ? 220 PHE D CD2 1 
ATOM   8277 C CE1 . PHE D 1 146 ? 101.722 108.901 157.213 1.00 34.64  ? 220 PHE D CE1 1 
ATOM   8278 C CE2 . PHE D 1 146 ? 103.656 109.342 158.538 1.00 33.89  ? 220 PHE D CE2 1 
ATOM   8279 C CZ  . PHE D 1 146 ? 102.554 108.563 158.256 1.00 34.60  ? 220 PHE D CZ  1 
ATOM   8280 N N   . GLN D 1 147 ? 100.890 112.937 157.958 1.00 28.20  ? 221 GLN D N   1 
ATOM   8281 C CA  . GLN D 1 147 ? 99.494  112.681 158.296 1.00 29.04  ? 221 GLN D CA  1 
ATOM   8282 C C   . GLN D 1 147 ? 98.598  113.820 157.827 1.00 37.54  ? 221 GLN D C   1 
ATOM   8283 O O   . GLN D 1 147 ? 97.571  113.592 157.176 1.00 43.26  ? 221 GLN D O   1 
ATOM   8284 C CB  . GLN D 1 147 ? 99.350  112.476 159.804 1.00 33.96  ? 221 GLN D CB  1 
ATOM   8285 C CG  . GLN D 1 147 ? 99.591  111.055 160.280 1.00 35.80  ? 221 GLN D CG  1 
ATOM   8286 C CD  . GLN D 1 147 ? 101.000 110.842 160.796 1.00 36.82  ? 221 GLN D CD  1 
ATOM   8287 O OE1 . GLN D 1 147 ? 101.750 111.796 160.998 1.00 42.25  ? 221 GLN D OE1 1 
ATOM   8288 N NE2 . GLN D 1 147 ? 101.361 109.586 161.027 1.00 35.16  ? 221 GLN D NE2 1 
ATOM   8289 N N   . SER D 1 148 ? 98.981  115.059 158.142 1.00 34.82  ? 222 SER D N   1 
ATOM   8290 C CA  . SER D 1 148 ? 98.165  116.208 157.767 1.00 31.85  ? 222 SER D CA  1 
ATOM   8291 C C   . SER D 1 148 ? 98.085  116.364 156.254 1.00 42.70  ? 222 SER D C   1 
ATOM   8292 O O   . SER D 1 148 ? 97.016  116.665 155.712 1.00 46.46  ? 222 SER D O   1 
ATOM   8293 C CB  . SER D 1 148 ? 98.722  117.478 158.409 1.00 36.80  ? 222 SER D CB  1 
ATOM   8294 O OG  . SER D 1 148 ? 98.049  118.629 157.929 1.00 44.49  ? 222 SER D OG  1 
ATOM   8295 N N   . GLN D 1 149 ? 99.205  116.165 155.555 1.00 37.56  ? 223 GLN D N   1 
ATOM   8296 C CA  . GLN D 1 149 ? 99.204  116.301 154.101 1.00 30.55  ? 223 GLN D CA  1 
ATOM   8297 C C   . GLN D 1 149 ? 98.319  115.247 153.445 1.00 33.58  ? 223 GLN D C   1 
ATOM   8298 O O   . GLN D 1 149 ? 97.536  115.561 152.538 1.00 41.41  ? 223 GLN D O   1 
ATOM   8299 C CB  . GLN D 1 149 ? 100.634 116.218 153.572 1.00 29.10  ? 223 GLN D CB  1 
ATOM   8300 C CG  . GLN D 1 149 ? 101.621 117.083 154.340 1.00 29.91  ? 223 GLN D CG  1 
ATOM   8301 C CD  . GLN D 1 149 ? 102.943 117.245 153.618 1.00 31.73  ? 223 GLN D CD  1 
ATOM   8302 O OE1 . GLN D 1 149 ? 103.112 118.154 152.806 1.00 33.03  ? 223 GLN D OE1 1 
ATOM   8303 N NE2 . GLN D 1 149 ? 103.889 116.363 153.913 1.00 35.33  ? 223 GLN D NE2 1 
ATOM   8304 N N   . VAL D 1 150 ? 98.421  113.994 153.895 1.00 30.14  ? 224 VAL D N   1 
ATOM   8305 C CA  . VAL D 1 150 ? 97.577  112.938 153.343 1.00 25.31  ? 224 VAL D CA  1 
ATOM   8306 C C   . VAL D 1 150 ? 96.111  113.216 153.645 1.00 34.30  ? 224 VAL D C   1 
ATOM   8307 O O   . VAL D 1 150 ? 95.236  112.994 152.799 1.00 44.44  ? 224 VAL D O   1 
ATOM   8308 C CB  . VAL D 1 150 ? 98.020  111.561 153.873 1.00 26.13  ? 224 VAL D CB  1 
ATOM   8309 C CG1 . VAL D 1 150 ? 97.050  110.482 153.427 1.00 31.33  ? 224 VAL D CG1 1 
ATOM   8310 C CG2 . VAL D 1 150 ? 99.419  111.235 153.383 1.00 32.29  ? 224 VAL D CG2 1 
ATOM   8311 N N   . THR D 1 151 ? 95.816  113.714 154.849 1.00 30.61  ? 225 THR D N   1 
ATOM   8312 C CA  . THR D 1 151 ? 94.434  114.033 155.190 1.00 31.91  ? 225 THR D CA  1 
ATOM   8313 C C   . THR D 1 151 ? 93.886  115.145 154.304 1.00 38.92  ? 225 THR D C   1 
ATOM   8314 O O   . THR D 1 151 ? 92.747  115.067 153.831 1.00 43.12  ? 225 THR D O   1 
ATOM   8315 C CB  . THR D 1 151 ? 94.333  114.423 156.664 1.00 33.70  ? 225 THR D CB  1 
ATOM   8316 O OG1 . THR D 1 151 ? 95.134  113.532 157.449 1.00 42.10  ? 225 THR D OG1 1 
ATOM   8317 C CG2 . THR D 1 151 ? 92.890  114.346 157.136 1.00 37.77  ? 225 THR D CG2 1 
ATOM   8318 N N   . GLN D 1 152 ? 94.685  116.188 154.064 1.00 40.49  ? 226 GLN D N   1 
ATOM   8319 C CA  . GLN D 1 152 ? 94.240  117.277 153.198 1.00 33.79  ? 226 GLN D CA  1 
ATOM   8320 C C   . GLN D 1 152 ? 94.029  116.794 151.769 1.00 36.52  ? 226 GLN D C   1 
ATOM   8321 O O   . GLN D 1 152 ? 93.096  117.236 151.089 1.00 43.30  ? 226 GLN D O   1 
ATOM   8322 C CB  . GLN D 1 152 ? 95.243  118.430 153.232 1.00 31.68  ? 226 GLN D CB  1 
ATOM   8323 C CG  . GLN D 1 152 ? 95.386  119.094 154.591 1.00 42.29  ? 226 GLN D CG  1 
ATOM   8324 C CD  . GLN D 1 152 ? 94.123  119.810 155.025 1.00 45.72  ? 226 GLN D CD  1 
ATOM   8325 O OE1 . GLN D 1 152 ? 93.438  120.433 154.214 1.00 49.18  ? 226 GLN D OE1 1 
ATOM   8326 N NE2 . GLN D 1 152 ? 93.808  119.726 156.313 1.00 43.98  ? 226 GLN D NE2 1 
ATOM   8327 N N   . VAL D 1 153 ? 94.892  115.895 151.292 1.00 37.40  ? 227 VAL D N   1 
ATOM   8328 C CA  . VAL D 1 153 ? 94.704  115.330 149.958 1.00 29.83  ? 227 VAL D CA  1 
ATOM   8329 C C   . VAL D 1 153 ? 93.414  114.520 149.897 1.00 31.59  ? 227 VAL D C   1 
ATOM   8330 O O   . VAL D 1 153 ? 92.653  114.610 148.925 1.00 44.92  ? 227 VAL D O   1 
ATOM   8331 C CB  . VAL D 1 153 ? 95.927  114.486 149.558 1.00 30.65  ? 227 VAL D CB  1 
ATOM   8332 C CG1 . VAL D 1 153 ? 95.618  113.655 148.328 1.00 32.85  ? 227 VAL D CG1 1 
ATOM   8333 C CG2 . VAL D 1 153 ? 97.120  115.390 149.300 1.00 37.69  ? 227 VAL D CG2 1 
ATOM   8334 N N   . ILE D 1 154 ? 93.145  113.722 150.932 1.00 33.59  ? 228 ILE D N   1 
ATOM   8335 C CA  . ILE D 1 154 ? 91.939  112.897 150.950 1.00 32.63  ? 228 ILE D CA  1 
ATOM   8336 C C   . ILE D 1 154 ? 90.690  113.769 150.978 1.00 38.27  ? 228 ILE D C   1 
ATOM   8337 O O   . ILE D 1 154 ? 89.697  113.476 150.301 1.00 40.36  ? 228 ILE D O   1 
ATOM   8338 C CB  . ILE D 1 154 ? 91.977  111.918 152.138 1.00 35.13  ? 228 ILE D CB  1 
ATOM   8339 C CG1 . ILE D 1 154 ? 93.055  110.856 151.923 1.00 37.61  ? 228 ILE D CG1 1 
ATOM   8340 C CG2 . ILE D 1 154 ? 90.622  111.258 152.338 1.00 41.70  ? 228 ILE D CG2 1 
ATOM   8341 C CD1 . ILE D 1 154 ? 93.232  109.921 153.098 1.00 40.23  ? 228 ILE D CD1 1 
ATOM   8342 N N   . GLU D 1 155 ? 90.717  114.854 151.758 1.00 41.14  ? 229 GLU D N   1 
ATOM   8343 C CA  . GLU D 1 155 ? 89.544  115.720 151.861 1.00 42.03  ? 229 GLU D CA  1 
ATOM   8344 C C   . GLU D 1 155 ? 89.172  116.319 150.510 1.00 45.87  ? 229 GLU D C   1 
ATOM   8345 O O   . GLU D 1 155 ? 87.990  116.368 150.150 1.00 47.00  ? 229 GLU D O   1 
ATOM   8346 C CB  . GLU D 1 155 ? 89.791  116.827 152.886 1.00 43.19  ? 229 GLU D CB  1 
ATOM   8347 C CG  . GLU D 1 155 ? 89.914  116.336 154.318 1.00 47.19  ? 229 GLU D CG  1 
ATOM   8348 C CD  . GLU D 1 155 ? 88.852  115.317 154.677 1.00 52.69  ? 229 GLU D CD  1 
ATOM   8349 O OE1 . GLU D 1 155 ? 87.661  115.690 154.725 1.00 50.49  ? 229 GLU D OE1 1 
ATOM   8350 O OE2 . GLU D 1 155 ? 89.207  114.143 154.913 1.00 50.48  ? 229 GLU D OE2 1 
ATOM   8351 N N   . GLY D 1 156 ? 90.161  116.777 149.748 1.00 49.44  ? 230 GLY D N   1 
ATOM   8352 C CA  . GLY D 1 156 ? 89.895  117.303 148.424 1.00 45.06  ? 230 GLY D CA  1 
ATOM   8353 C C   . GLY D 1 156 ? 90.358  118.730 148.220 1.00 38.38  ? 230 GLY D C   1 
ATOM   8354 O O   . GLY D 1 156 ? 89.925  119.398 147.277 1.00 43.49  ? 230 GLY D O   1 
ATOM   8355 N N   . ASN D 1 157 ? 91.237  119.209 149.093 1.00 40.39  ? 231 ASN D N   1 
ATOM   8356 C CA  . ASN D 1 157 ? 91.793  120.557 149.002 1.00 47.38  ? 231 ASN D CA  1 
ATOM   8357 C C   . ASN D 1 157 ? 93.253  120.425 148.574 1.00 51.60  ? 231 ASN D C   1 
ATOM   8358 O O   . ASN D 1 157 ? 94.160  120.402 149.407 1.00 56.93  ? 231 ASN D O   1 
ATOM   8359 C CB  . ASN D 1 157 ? 91.661  121.299 150.330 1.00 50.70  ? 231 ASN D CB  1 
ATOM   8360 C CG  . ASN D 1 157 ? 90.251  121.254 150.885 1.00 55.14  ? 231 ASN D CG  1 
ATOM   8361 O OD1 . ASN D 1 157 ? 89.306  120.892 150.185 1.00 57.31  ? 231 ASN D OD1 1 
ATOM   8362 N ND2 . ASN D 1 157 ? 90.103  121.623 152.152 1.00 54.08  ? 231 ASN D ND2 1 
ATOM   8363 N N   . ALA D 1 158 ? 93.471  120.349 147.263 1.00 46.71  ? 232 ALA D N   1 
ATOM   8364 C CA  . ALA D 1 158 ? 94.811  120.187 146.718 1.00 41.31  ? 232 ALA D CA  1 
ATOM   8365 C C   . ALA D 1 158 ? 94.786  120.512 145.233 1.00 44.27  ? 232 ALA D C   1 
ATOM   8366 O O   . ALA D 1 158 ? 93.788  120.272 144.549 1.00 51.90  ? 232 ALA D O   1 
ATOM   8367 C CB  . ALA D 1 158 ? 95.341  118.768 146.945 1.00 42.87  ? 232 ALA D CB  1 
ATOM   8368 N N   . ALA D 1 159 ? 95.895  121.058 144.746 1.00 37.78  ? 233 ALA D N   1 
ATOM   8369 C CA  . ALA D 1 159 ? 96.053  121.396 143.340 1.00 39.06  ? 233 ALA D CA  1 
ATOM   8370 C C   . ALA D 1 159 ? 96.943  120.372 142.647 1.00 38.36  ? 233 ALA D C   1 
ATOM   8371 O O   . ALA D 1 159 ? 97.816  119.759 143.267 1.00 44.38  ? 233 ALA D O   1 
ATOM   8372 C CB  . ALA D 1 159 ? 96.641  122.798 143.177 1.00 37.69  ? 233 ALA D CB  1 
ATOM   8373 N N   . VAL D 1 160 ? 96.711  120.191 141.346 1.00 31.91  ? 234 VAL D N   1 
ATOM   8374 C CA  . VAL D 1 160 ? 97.426  119.204 140.550 1.00 32.62  ? 234 VAL D CA  1 
ATOM   8375 C C   . VAL D 1 160 ? 97.918  119.855 139.266 1.00 33.10  ? 234 VAL D C   1 
ATOM   8376 O O   . VAL D 1 160 ? 97.447  120.918 138.856 1.00 45.22  ? 234 VAL D O   1 
ATOM   8377 C CB  . VAL D 1 160 ? 96.552  117.974 140.218 1.00 32.11  ? 234 VAL D CB  1 
ATOM   8378 C CG1 . VAL D 1 160 ? 96.133  117.253 141.489 1.00 39.50  ? 234 VAL D CG1 1 
ATOM   8379 C CG2 . VAL D 1 160 ? 95.337  118.391 139.407 1.00 35.77  ? 234 VAL D CG2 1 
ATOM   8380 N N   . VAL D 1 161 ? 98.886  119.199 138.631 1.00 26.18  ? 235 VAL D N   1 
ATOM   8381 C CA  . VAL D 1 161 ? 99.359  119.571 137.305 1.00 24.45  ? 235 VAL D CA  1 
ATOM   8382 C C   . VAL D 1 161 ? 99.078  118.413 136.359 1.00 30.46  ? 235 VAL D C   1 
ATOM   8383 O O   . VAL D 1 161 ? 99.320  117.248 136.694 1.00 37.48  ? 235 VAL D O   1 
ATOM   8384 C CB  . VAL D 1 161 ? 100.858 119.947 137.297 1.00 21.61  ? 235 VAL D CB  1 
ATOM   8385 C CG1 . VAL D 1 161 ? 101.105 121.117 138.214 1.00 29.56  ? 235 VAL D CG1 1 
ATOM   8386 C CG2 . VAL D 1 161 ? 101.724 118.776 137.710 1.00 29.26  ? 235 VAL D CG2 1 
ATOM   8387 N N   . LEU D 1 162 ? 98.528  118.731 135.190 1.00 27.79  ? 236 LEU D N   1 
ATOM   8388 C CA  . LEU D 1 162 ? 98.184  117.716 134.198 1.00 24.48  ? 236 LEU D CA  1 
ATOM   8389 C C   . LEU D 1 162 ? 99.409  117.483 133.325 1.00 30.34  ? 236 LEU D C   1 
ATOM   8390 O O   . LEU D 1 162 ? 99.568  118.083 132.261 1.00 39.42  ? 236 LEU D O   1 
ATOM   8391 C CB  . LEU D 1 162 ? 96.974  118.150 133.381 1.00 32.88  ? 236 LEU D CB  1 
ATOM   8392 C CG  . LEU D 1 162 ? 95.645  118.150 134.138 1.00 32.28  ? 236 LEU D CG  1 
ATOM   8393 C CD1 . LEU D 1 162 ? 94.487  118.475 133.206 1.00 35.53  ? 236 LEU D CD1 1 
ATOM   8394 C CD2 . LEU D 1 162 ? 95.424  116.822 134.842 1.00 33.76  ? 236 LEU D CD2 1 
ATOM   8395 N N   . ARG D 1 163 ? 100.289 116.597 133.784 1.00 24.04  ? 237 ARG D N   1 
ATOM   8396 C CA  . ARG D 1 163 ? 101.518 116.314 133.056 1.00 24.74  ? 237 ARG D CA  1 
ATOM   8397 C C   . ARG D 1 163 ? 101.212 115.512 131.798 1.00 31.56  ? 237 ARG D C   1 
ATOM   8398 O O   . ARG D 1 163 ? 100.577 114.456 131.861 1.00 35.89  ? 237 ARG D O   1 
ATOM   8399 C CB  . ARG D 1 163 ? 102.495 115.550 133.945 1.00 25.35  ? 237 ARG D CB  1 
ATOM   8400 C CG  . ARG D 1 163 ? 102.961 116.323 135.164 1.00 25.10  ? 237 ARG D CG  1 
ATOM   8401 C CD  . ARG D 1 163 ? 104.102 115.610 135.863 1.00 24.08  ? 237 ARG D CD  1 
ATOM   8402 N NE  . ARG D 1 163 ? 104.553 116.334 137.044 1.00 24.28  ? 237 ARG D NE  1 
ATOM   8403 C CZ  . ARG D 1 163 ? 105.486 117.276 137.034 1.00 23.50  ? 237 ARG D CZ  1 
ATOM   8404 N NH1 . ARG D 1 163 ? 106.090 117.638 135.916 1.00 25.39  ? 237 ARG D NH1 1 
ATOM   8405 N NH2 . ARG D 1 163 ? 105.819 117.871 138.176 1.00 23.49  ? 237 ARG D NH2 1 
ATOM   8406 N N   . SER D 1 164 ? 101.673 116.013 130.657 1.00 27.51  ? 238 SER D N   1 
ATOM   8407 C CA  . SER D 1 164 ? 101.417 115.344 129.391 1.00 19.20  ? 238 SER D CA  1 
ATOM   8408 C C   . SER D 1 164 ? 102.270 114.087 129.260 1.00 27.77  ? 238 SER D C   1 
ATOM   8409 O O   . SER D 1 164 ? 103.355 113.977 129.836 1.00 34.83  ? 238 SER D O   1 
ATOM   8410 C CB  . SER D 1 164 ? 101.695 116.288 128.223 1.00 30.85  ? 238 SER D CB  1 
ATOM   8411 O OG  . SER D 1 164 ? 100.919 117.468 128.325 1.00 41.30  ? 238 SER D OG  1 
ATOM   8412 N N   . ARG D 1 165 ? 101.761 113.133 128.486 1.00 27.55  ? 239 ARG D N   1 
ATOM   8413 C CA  . ARG D 1 165 ? 102.459 111.894 128.191 1.00 20.76  ? 239 ARG D CA  1 
ATOM   8414 C C   . ARG D 1 165 ? 102.448 111.671 126.686 1.00 27.18  ? 239 ARG D C   1 
ATOM   8415 O O   . ARG D 1 165 ? 101.601 112.208 125.967 1.00 38.92  ? 239 ARG D O   1 
ATOM   8416 C CB  . ARG D 1 165 ? 101.818 110.697 128.905 1.00 27.35  ? 239 ARG D CB  1 
ATOM   8417 C CG  . ARG D 1 165 ? 101.890 110.759 130.419 1.00 25.30  ? 239 ARG D CG  1 
ATOM   8418 C CD  . ARG D 1 165 ? 101.653 109.392 131.034 1.00 26.18  ? 239 ARG D CD  1 
ATOM   8419 N NE  . ARG D 1 165 ? 100.342 108.859 130.688 1.00 25.96  ? 239 ARG D NE  1 
ATOM   8420 C CZ  . ARG D 1 165 ? 99.877  107.688 131.099 1.00 24.96  ? 239 ARG D CZ  1 
ATOM   8421 N NH1 . ARG D 1 165 ? 100.591 106.897 131.881 1.00 25.97  ? 239 ARG D NH1 1 
ATOM   8422 N NH2 . ARG D 1 165 ? 98.663  107.303 130.718 1.00 32.07  ? 239 ARG D NH2 1 
ATOM   8423 N N   . LEU D 1 166 ? 103.398 110.874 126.209 1.00 31.82  ? 240 LEU D N   1 
ATOM   8424 C CA  . LEU D 1 166 ? 103.500 110.571 124.788 1.00 21.26  ? 240 LEU D CA  1 
ATOM   8425 C C   . LEU D 1 166 ? 102.999 109.160 124.513 1.00 29.17  ? 240 LEU D C   1 
ATOM   8426 O O   . LEU D 1 166 ? 103.428 108.199 125.162 1.00 38.55  ? 240 LEU D O   1 
ATOM   8427 C CB  . LEU D 1 166 ? 104.934 110.725 124.283 1.00 21.19  ? 240 LEU D CB  1 
ATOM   8428 C CG  . LEU D 1 166 ? 105.493 112.142 124.156 1.00 30.50  ? 240 LEU D CG  1 
ATOM   8429 C CD1 . LEU D 1 166 ? 106.989 112.100 123.892 1.00 32.92  ? 240 LEU D CD1 1 
ATOM   8430 C CD2 . LEU D 1 166 ? 104.772 112.921 123.069 1.00 29.55  ? 240 LEU D CD2 1 
ATOM   8431 N N   . LYS D 1 167 ? 102.084 109.055 123.555 1.00 29.57  ? 241 LYS D N   1 
ATOM   8432 C CA  . LYS D 1 167 ? 101.607 107.784 123.025 1.00 24.84  ? 241 LYS D CA  1 
ATOM   8433 C C   . LYS D 1 167 ? 102.548 107.366 121.902 1.00 34.30  ? 241 LYS D C   1 
ATOM   8434 O O   . LYS D 1 167 ? 102.660 108.065 120.888 1.00 38.06  ? 241 LYS D O   1 
ATOM   8435 C CB  . LYS D 1 167 ? 100.175 107.935 122.522 1.00 30.72  ? 241 LYS D CB  1 
ATOM   8436 C CG  . LYS D 1 167 ? 99.514  106.672 122.012 1.00 31.72  ? 241 LYS D CG  1 
ATOM   8437 C CD  . LYS D 1 167 ? 98.080  106.972 121.598 1.00 34.55  ? 241 LYS D CD  1 
ATOM   8438 C CE  . LYS D 1 167 ? 97.336  105.725 121.160 1.00 37.95  ? 241 LYS D CE  1 
ATOM   8439 N NZ  . LYS D 1 167 ? 97.891  105.180 119.892 1.00 38.73  ? 241 LYS D NZ  1 
ATOM   8440 N N   . VAL D 1 168 ? 103.230 106.237 122.079 1.00 35.07  ? 242 VAL D N   1 
ATOM   8441 C CA  . VAL D 1 168 ? 104.220 105.762 121.122 1.00 23.99  ? 242 VAL D CA  1 
ATOM   8442 C C   . VAL D 1 168 ? 103.825 104.367 120.657 1.00 31.83  ? 242 VAL D C   1 
ATOM   8443 O O   . VAL D 1 168 ? 103.461 103.510 121.471 1.00 43.24  ? 242 VAL D O   1 
ATOM   8444 C CB  . VAL D 1 168 ? 105.641 105.788 121.719 1.00 32.23  ? 242 VAL D CB  1 
ATOM   8445 C CG1 . VAL D 1 168 ? 105.723 104.938 122.967 1.00 41.56  ? 242 VAL D CG1 1 
ATOM   8446 C CG2 . VAL D 1 168 ? 106.658 105.323 120.694 1.00 35.45  ? 242 VAL D CG2 1 
ATOM   8447 N N   . ARG D 1 169 ? 103.865 104.158 119.344 1.00 37.24  ? 243 ARG D N   1 
ATOM   8448 C CA  . ARG D 1 169 ? 103.516 102.892 118.716 1.00 38.21  ? 243 ARG D CA  1 
ATOM   8449 C C   . ARG D 1 169 ? 104.684 102.428 117.861 1.00 41.27  ? 243 ARG D C   1 
ATOM   8450 O O   . ARG D 1 169 ? 105.190 103.191 117.032 1.00 44.64  ? 243 ARG D O   1 
ATOM   8451 C CB  . ARG D 1 169 ? 102.258 103.032 117.854 1.00 41.22  ? 243 ARG D CB  1 
ATOM   8452 C CG  . ARG D 1 169 ? 100.996 103.357 118.631 1.00 45.33  ? 243 ARG D CG  1 
ATOM   8453 C CD  . ARG D 1 169 ? 99.808  103.500 117.696 1.00 45.69  ? 243 ARG D CD  1 
ATOM   8454 N NE  . ARG D 1 169 ? 99.465  102.237 117.054 1.00 49.06  ? 243 ARG D NE  1 
ATOM   8455 C CZ  . ARG D 1 169 ? 99.655  101.978 115.768 1.00 50.92  ? 243 ARG D CZ  1 
ATOM   8456 N NH1 . ARG D 1 169 ? 100.185 102.875 114.953 1.00 49.62  ? 243 ARG D NH1 1 
ATOM   8457 N NH2 . ARG D 1 169 ? 99.305  100.788 115.287 1.00 48.65  ? 243 ARG D NH2 1 
ATOM   8458 N N   . VAL D 1 170 ? 105.107 101.183 118.053 1.00 41.09  ? 244 VAL D N   1 
ATOM   8459 C CA  . VAL D 1 170 ? 106.216 100.602 117.306 1.00 38.49  ? 244 VAL D CA  1 
ATOM   8460 C C   . VAL D 1 170 ? 105.644 99.585  116.329 1.00 43.47  ? 244 VAL D C   1 
ATOM   8461 O O   . VAL D 1 170 ? 104.989 98.619  116.740 1.00 48.77  ? 244 VAL D O   1 
ATOM   8462 C CB  . VAL D 1 170 ? 107.251 99.954  118.237 1.00 34.87  ? 244 VAL D CB  1 
ATOM   8463 C CG1 . VAL D 1 170 ? 108.521 99.627  117.471 1.00 44.27  ? 244 VAL D CG1 1 
ATOM   8464 C CG2 . VAL D 1 170 ? 107.554 100.872 119.409 1.00 38.00  ? 244 VAL D CG2 1 
ATOM   8465 N N   . VAL D 1 171 ? 105.892 99.798  115.040 1.00 45.50  ? 245 VAL D N   1 
ATOM   8466 C CA  . VAL D 1 171 ? 105.416 98.912  113.984 1.00 42.14  ? 245 VAL D CA  1 
ATOM   8467 C C   . VAL D 1 171 ? 106.617 98.166  113.422 1.00 47.62  ? 245 VAL D C   1 
ATOM   8468 O O   . VAL D 1 171 ? 107.571 98.787  112.933 1.00 51.77  ? 245 VAL D O   1 
ATOM   8469 C CB  . VAL D 1 171 ? 104.679 99.686  112.881 1.00 45.70  ? 245 VAL D CB  1 
ATOM   8470 C CG1 . VAL D 1 171 ? 104.265 98.744  111.761 1.00 47.56  ? 245 VAL D CG1 1 
ATOM   8471 C CG2 . VAL D 1 171 ? 103.469 100.402 113.455 1.00 45.94  ? 245 VAL D CG2 1 
ATOM   8472 N N   . LYS D 1 172 ? 106.570 96.839  113.490 1.00 54.32  ? 246 LYS D N   1 
ATOM   8473 C CA  . LYS D 1 172 ? 107.648 95.979  113.025 1.00 52.98  ? 246 LYS D CA  1 
ATOM   8474 C C   . LYS D 1 172 ? 107.177 95.166  111.828 1.00 57.89  ? 246 LYS D C   1 
ATOM   8475 O O   . LYS D 1 172 ? 106.073 94.610  111.844 1.00 57.14  ? 246 LYS D O   1 
ATOM   8476 C CB  . LYS D 1 172 ? 108.128 95.047  114.140 1.00 49.88  ? 246 LYS D CB  1 
ATOM   8477 C CG  . LYS D 1 172 ? 108.843 95.757  115.278 1.00 53.24  ? 246 LYS D CG  1 
ATOM   8478 C CD  . LYS D 1 172 ? 109.331 94.774  116.327 1.00 55.42  ? 246 LYS D CD  1 
ATOM   8479 C CE  . LYS D 1 172 ? 110.029 95.492  117.470 1.00 54.80  ? 246 LYS D CE  1 
ATOM   8480 N NZ  . LYS D 1 172 ? 110.502 94.547  118.518 1.00 53.85  ? 246 LYS D NZ  1 
ATOM   8481 N N   . GLU D 1 173 ? 108.013 95.101  110.796 1.00 63.30  ? 247 GLU D N   1 
ATOM   8482 C CA  . GLU D 1 173 ? 107.691 94.344  109.593 1.00 61.24  ? 247 GLU D CA  1 
ATOM   8483 C C   . GLU D 1 173 ? 108.399 92.993  109.593 1.00 61.47  ? 247 GLU D C   1 
ATOM   8484 O O   . GLU D 1 173 ? 108.803 92.494  110.643 1.00 61.49  ? 247 GLU D O   1 
ATOM   8485 C CB  . GLU D 1 173 ? 108.070 95.139  108.342 1.00 58.75  ? 247 GLU D CB  1 
ATOM   8486 C CG  . GLU D 1 173 ? 107.702 94.453  107.035 1.00 62.17  ? 247 GLU D CG  1 
ATOM   8487 C CD  . GLU D 1 173 ? 108.050 95.293  105.820 1.00 65.58  ? 247 GLU D CD  1 
ATOM   8488 O OE1 . GLU D 1 173 ? 108.612 96.393  105.998 1.00 64.07  ? 247 GLU D OE1 1 
ATOM   8489 O OE2 . GLU D 1 173 ? 107.758 94.853  104.688 1.00 64.02  ? 247 GLU D OE2 1 
ATOM   8490 N N   . ALA D 1 203 ? 102.186 96.381  116.614 1.00 53.27  ? 277 ALA D N   1 
ATOM   8491 C CA  . ALA D 1 203 ? 101.995 97.484  117.549 1.00 58.02  ? 277 ALA D CA  1 
ATOM   8492 C C   . ALA D 1 203 ? 102.313 97.046  118.974 1.00 56.33  ? 277 ALA D C   1 
ATOM   8493 O O   . ALA D 1 203 ? 102.113 95.887  119.334 1.00 58.10  ? 277 ALA D O   1 
ATOM   8494 C CB  . ALA D 1 203 ? 100.574 98.015  117.460 1.00 56.98  ? 277 ALA D CB  1 
ATOM   8495 N N   . MET D 1 204 ? 102.810 97.981  119.783 1.00 50.35  ? 278 MET D N   1 
ATOM   8496 C CA  . MET D 1 204 ? 103.151 97.673  121.166 1.00 52.39  ? 278 MET D CA  1 
ATOM   8497 C C   . MET D 1 204 ? 102.474 98.652  122.120 1.00 59.17  ? 278 MET D C   1 
ATOM   8498 O O   . MET D 1 204 ? 102.187 98.303  123.270 1.00 61.27  ? 278 MET D O   1 
ATOM   8499 C CB  . MET D 1 204 ? 104.667 97.682  121.355 1.00 53.01  ? 278 MET D CB  1 
ATOM   8500 C CG  . MET D 1 204 ? 105.390 96.584  120.591 1.00 56.76  ? 278 MET D CG  1 
ATOM   8501 S SD  . MET D 1 204 ? 104.883 94.927  121.090 1.00 69.18  ? 278 MET D SD  1 
ATOM   8502 C CE  . MET D 1 204 ? 105.568 94.839  122.742 1.00 55.40  ? 278 MET D CE  1 
ATOM   8503 N N   . GLN D 1 205 ? 102.218 99.875  121.649 1.00 48.20  ? 279 GLN D N   1 
ATOM   8504 C CA  . GLN D 1 205 ? 101.330 100.829 122.317 1.00 42.45  ? 279 GLN D CA  1 
ATOM   8505 C C   . GLN D 1 205 ? 101.822 101.162 123.732 1.00 43.79  ? 279 GLN D C   1 
ATOM   8506 O O   . GLN D 1 205 ? 101.214 100.802 124.743 1.00 50.06  ? 279 GLN D O   1 
ATOM   8507 C CB  . GLN D 1 205 ? 99.894  100.287 122.327 1.00 47.60  ? 279 GLN D CB  1 
ATOM   8508 C CG  . GLN D 1 205 ? 98.855  101.228 122.912 1.00 47.01  ? 279 GLN D CG  1 
ATOM   8509 C CD  . GLN D 1 205 ? 98.740  102.513 122.128 1.00 46.89  ? 279 GLN D CD  1 
ATOM   8510 O OE1 . GLN D 1 205 ? 99.219  103.559 122.561 1.00 50.95  ? 279 GLN D OE1 1 
ATOM   8511 N NE2 . GLN D 1 205 ? 98.106  102.442 120.965 1.00 48.26  ? 279 GLN D NE2 1 
ATOM   8512 N N   . TYR D 1 206 ? 102.966 101.837 123.780 1.00 41.43  ? 280 TYR D N   1 
ATOM   8513 C CA  . TYR D 1 206 ? 103.484 102.318 125.052 1.00 35.47  ? 280 TYR D CA  1 
ATOM   8514 C C   . TYR D 1 206 ? 103.034 103.753 125.327 1.00 40.79  ? 280 TYR D C   1 
ATOM   8515 O O   . TYR D 1 206 ? 102.746 104.536 124.416 1.00 48.19  ? 280 TYR D O   1 
ATOM   8516 C CB  . TYR D 1 206 ? 105.011 102.263 125.099 1.00 39.19  ? 280 TYR D CB  1 
ATOM   8517 C CG  . TYR D 1 206 ? 105.632 100.927 124.774 1.00 41.84  ? 280 TYR D CG  1 
ATOM   8518 C CD1 . TYR D 1 206 ? 105.725 99.930  125.734 1.00 44.83  ? 280 TYR D CD1 1 
ATOM   8519 C CD2 . TYR D 1 206 ? 106.178 100.684 123.523 1.00 42.66  ? 280 TYR D CD2 1 
ATOM   8520 C CE1 . TYR D 1 206 ? 106.310 98.712  125.443 1.00 46.74  ? 280 TYR D CE1 1 
ATOM   8521 C CE2 . TYR D 1 206 ? 106.771 99.476  123.227 1.00 42.25  ? 280 TYR D CE2 1 
ATOM   8522 C CZ  . TYR D 1 206 ? 106.831 98.492  124.187 1.00 44.13  ? 280 TYR D CZ  1 
ATOM   8523 O OH  . TYR D 1 206 ? 107.419 97.284  123.890 1.00 48.67  ? 280 TYR D OH  1 
ATOM   8524 N N   . GLN D 1 207 ? 102.980 104.087 126.615 1.00 38.51  ? 281 GLN D N   1 
ATOM   8525 C CA  . GLN D 1 207 ? 102.781 105.448 127.094 1.00 31.87  ? 281 GLN D CA  1 
ATOM   8526 C C   . GLN D 1 207 ? 104.011 105.848 127.895 1.00 35.40  ? 281 GLN D C   1 
ATOM   8527 O O   . GLN D 1 207 ? 104.400 105.139 128.828 1.00 46.78  ? 281 GLN D O   1 
ATOM   8528 C CB  . GLN D 1 207 ? 101.530 105.557 127.970 1.00 31.75  ? 281 GLN D CB  1 
ATOM   8529 C CG  . GLN D 1 207 ? 100.267 104.975 127.360 1.00 35.89  ? 281 GLN D CG  1 
ATOM   8530 C CD  . GLN D 1 207 ? 99.678  105.858 126.282 1.00 39.66  ? 281 GLN D CD  1 
ATOM   8531 O OE1 . GLN D 1 207 ? 99.468  107.052 126.491 1.00 40.94  ? 281 GLN D OE1 1 
ATOM   8532 N NE2 . GLN D 1 207 ? 99.403  105.275 125.122 1.00 43.98  ? 281 GLN D NE2 1 
ATOM   8533 N N   . VAL D 1 208 ? 104.622 106.975 127.538 1.00 26.76  ? 282 VAL D N   1 
ATOM   8534 C CA  . VAL D 1 208 ? 105.849 107.407 128.196 1.00 20.54  ? 282 VAL D CA  1 
ATOM   8535 C C   . VAL D 1 208 ? 105.627 108.764 128.846 1.00 21.97  ? 282 VAL D C   1 
ATOM   8536 O O   . VAL D 1 208 ? 104.795 109.564 128.405 1.00 30.40  ? 282 VAL D O   1 
ATOM   8537 C CB  . VAL D 1 208 ? 107.048 107.456 127.224 1.00 22.46  ? 282 VAL D CB  1 
ATOM   8538 C CG1 . VAL D 1 208 ? 107.302 106.083 126.631 1.00 34.63  ? 282 VAL D CG1 1 
ATOM   8539 C CG2 . VAL D 1 208 ? 106.812 108.470 126.133 1.00 31.26  ? 282 VAL D CG2 1 
ATOM   8540 N N   . LEU D 1 209 ? 106.391 109.018 129.910 1.00 31.23  ? 283 LEU D N   1 
ATOM   8541 C CA  . LEU D 1 209 ? 106.275 110.233 130.708 1.00 31.52  ? 283 LEU D CA  1 
ATOM   8542 C C   . LEU D 1 209 ? 107.371 111.248 130.409 1.00 36.70  ? 283 LEU D C   1 
ATOM   8543 O O   . LEU D 1 209 ? 107.071 112.406 130.103 1.00 43.96  ? 283 LEU D O   1 
ATOM   8544 C CB  . LEU D 1 209 ? 106.292 109.884 132.200 1.00 37.75  ? 283 LEU D CB  1 
ATOM   8545 C CG  . LEU D 1 209 ? 106.036 111.044 133.164 1.00 35.26  ? 283 LEU D CG  1 
ATOM   8546 C CD1 . LEU D 1 209 ? 104.752 111.780 132.811 1.00 38.52  ? 283 LEU D CD1 1 
ATOM   8547 C CD2 . LEU D 1 209 ? 106.008 110.553 134.600 1.00 34.51  ? 283 LEU D CD2 1 
ATOM   8548 N N   . ASN D 1 210 ? 108.640 110.848 130.499 1.00 35.21  ? 284 ASN D N   1 
ATOM   8549 C CA  . ASN D 1 210 ? 109.731 111.794 130.284 1.00 34.35  ? 284 ASN D CA  1 
ATOM   8550 C C   . ASN D 1 210 ? 110.107 111.910 128.808 1.00 40.04  ? 284 ASN D C   1 
ATOM   8551 O O   . ASN D 1 210 ? 109.987 112.989 128.219 1.00 43.51  ? 284 ASN D O   1 
ATOM   8552 C CB  . ASN D 1 210 ? 110.950 111.397 131.124 1.00 34.43  ? 284 ASN D CB  1 
ATOM   8553 C CG  . ASN D 1 210 ? 110.790 111.735 132.588 1.00 41.79  ? 284 ASN D CG  1 
ATOM   8554 O OD1 . ASN D 1 210 ? 110.231 112.773 132.941 1.00 44.62  ? 284 ASN D OD1 1 
ATOM   8555 N ND2 . ASN D 1 210 ? 111.316 110.878 133.450 1.00 42.94  ? 284 ASN D ND2 1 
ATOM   8556 N N   . GLU D 1 211 ? 110.552 110.815 128.193 1.00 36.47  ? 285 GLU D N   1 
ATOM   8557 C CA  . GLU D 1 211 ? 110.824 110.824 126.761 1.00 32.65  ? 285 GLU D CA  1 
ATOM   8558 C C   . GLU D 1 211 ? 110.833 109.394 126.242 1.00 29.76  ? 285 GLU D C   1 
ATOM   8559 O O   . GLU D 1 211 ? 110.713 108.429 127.001 1.00 45.14  ? 285 GLU D O   1 
ATOM   8560 C CB  . GLU D 1 211 ? 112.163 111.485 126.410 1.00 40.75  ? 285 GLU D CB  1 
ATOM   8561 C CG  . GLU D 1 211 ? 113.410 110.714 126.830 1.00 40.28  ? 285 GLU D CG  1 
ATOM   8562 C CD  . GLU D 1 211 ? 114.167 111.342 127.973 1.00 40.87  ? 285 GLU D CD  1 
ATOM   8563 O OE1 . GLU D 1 211 ? 113.613 112.223 128.648 1.00 47.23  ? 285 GLU D OE1 1 
ATOM   8564 O OE2 . GLU D 1 211 ? 115.330 110.949 128.195 1.00 46.14  ? 285 GLU D OE2 1 
ATOM   8565 N N   . VAL D 1 212 ? 110.983 109.277 124.927 1.00 26.10  ? 286 VAL D N   1 
ATOM   8566 C CA  . VAL D 1 212 ? 111.376 108.042 124.262 1.00 29.91  ? 286 VAL D CA  1 
ATOM   8567 C C   . VAL D 1 212 ? 112.667 108.327 123.503 1.00 26.73  ? 286 VAL D C   1 
ATOM   8568 O O   . VAL D 1 212 ? 112.763 109.327 122.782 1.00 29.11  ? 286 VAL D O   1 
ATOM   8569 C CB  . VAL D 1 212 ? 110.265 107.510 123.336 1.00 23.28  ? 286 VAL D CB  1 
ATOM   8570 C CG1 . VAL D 1 212 ? 109.890 108.529 122.274 1.00 22.88  ? 286 VAL D CG1 1 
ATOM   8571 C CG2 . VAL D 1 212 ? 110.698 106.212 122.688 1.00 37.02  ? 286 VAL D CG2 1 
ATOM   8572 N N   . VAL D 1 213 ? 113.670 107.475 123.695 1.00 30.76  ? 287 VAL D N   1 
ATOM   8573 C CA  . VAL D 1 213 ? 115.020 107.725 123.200 1.00 28.40  ? 287 VAL D CA  1 
ATOM   8574 C C   . VAL D 1 213 ? 115.338 106.708 122.114 1.00 37.29  ? 287 VAL D C   1 
ATOM   8575 O O   . VAL D 1 213 ? 115.256 105.497 122.344 1.00 45.94  ? 287 VAL D O   1 
ATOM   8576 C CB  . VAL D 1 213 ? 116.060 107.663 124.330 1.00 28.24  ? 287 VAL D CB  1 
ATOM   8577 C CG1 . VAL D 1 213 ? 117.455 107.475 123.759 1.00 34.23  ? 287 VAL D CG1 1 
ATOM   8578 C CG2 . VAL D 1 213 ? 116.003 108.919 125.173 1.00 34.30  ? 287 VAL D CG2 1 
ATOM   8579 N N   . ILE D 1 214 ? 115.711 107.201 120.937 1.00 38.22  ? 288 ILE D N   1 
ATOM   8580 C CA  . ILE D 1 214 ? 116.184 106.368 119.838 1.00 32.98  ? 288 ILE D CA  1 
ATOM   8581 C C   . ILE D 1 214 ? 117.666 106.656 119.662 1.00 31.90  ? 288 ILE D C   1 
ATOM   8582 O O   . ILE D 1 214 ? 118.043 107.763 119.261 1.00 37.76  ? 288 ILE D O   1 
ATOM   8583 C CB  . ILE D 1 214 ? 115.408 106.636 118.538 1.00 28.34  ? 288 ILE D CB  1 
ATOM   8584 C CG1 . ILE D 1 214 ? 113.924 106.302 118.713 1.00 38.44  ? 288 ILE D CG1 1 
ATOM   8585 C CG2 . ILE D 1 214 ? 116.001 105.836 117.390 1.00 37.49  ? 288 ILE D CG2 1 
ATOM   8586 C CD1 . ILE D 1 214 ? 113.071 107.467 119.172 1.00 39.18  ? 288 ILE D CD1 1 
ATOM   8587 N N   . ASP D 1 215 ? 118.502 105.667 119.950 1.00 39.97  ? 289 ASP D N   1 
ATOM   8588 C CA  . ASP D 1 215 ? 119.943 105.871 120.014 1.00 41.04  ? 289 ASP D CA  1 
ATOM   8589 C C   . ASP D 1 215 ? 120.649 104.623 119.491 1.00 47.34  ? 289 ASP D C   1 
ATOM   8590 O O   . ASP D 1 215 ? 120.042 103.784 118.818 1.00 51.85  ? 289 ASP D O   1 
ATOM   8591 C CB  . ASP D 1 215 ? 120.352 106.285 121.443 1.00 46.16  ? 289 ASP D CB  1 
ATOM   8592 C CG  . ASP D 1 215 ? 120.253 105.147 122.463 1.00 51.67  ? 289 ASP D CG  1 
ATOM   8593 O OD1 . ASP D 1 215 ? 120.178 103.957 122.091 1.00 51.93  ? 289 ASP D OD1 1 
ATOM   8594 O OD2 . ASP D 1 215 ? 120.231 105.461 123.670 1.00 52.52  ? 289 ASP D OD2 1 
ATOM   8595 N N   . ARG D 1 216 ? 121.941 104.514 119.786 1.00 49.98  ? 290 ARG D N   1 
ATOM   8596 C CA  . ARG D 1 216 ? 122.758 103.373 119.407 1.00 46.73  ? 290 ARG D CA  1 
ATOM   8597 C C   . ARG D 1 216 ? 123.183 102.614 120.656 1.00 48.33  ? 290 ARG D C   1 
ATOM   8598 O O   . ARG D 1 216 ? 123.430 103.217 121.705 1.00 50.72  ? 290 ARG D O   1 
ATOM   8599 C CB  . ARG D 1 216 ? 123.997 103.818 118.628 1.00 48.80  ? 290 ARG D CB  1 
ATOM   8600 C CG  . ARG D 1 216 ? 124.682 105.040 119.215 1.00 52.75  ? 290 ARG D CG  1 
ATOM   8601 C CD  . ARG D 1 216 ? 126.036 105.268 118.572 1.00 54.87  ? 290 ARG D CD  1 
ATOM   8602 N NE  . ARG D 1 216 ? 126.734 106.414 119.144 1.00 52.44  ? 290 ARG D NE  1 
ATOM   8603 C CZ  . ARG D 1 216 ? 127.565 106.343 120.175 1.00 52.82  ? 290 ARG D CZ  1 
ATOM   8604 N NH1 . ARG D 1 216 ? 127.823 105.195 120.778 1.00 52.81  ? 290 ARG D NH1 1 
ATOM   8605 N NH2 . ARG D 1 216 ? 128.155 107.453 120.610 1.00 54.27  ? 290 ARG D NH2 1 
ATOM   8606 N N   . GLY D 1 217 ? 123.267 101.293 120.541 1.00 58.54  ? 291 GLY D N   1 
ATOM   8607 C CA  . GLY D 1 217 ? 123.660 100.463 121.653 1.00 61.51  ? 291 GLY D CA  1 
ATOM   8608 C C   . GLY D 1 217 ? 125.132 100.111 121.611 1.00 60.41  ? 291 GLY D C   1 
ATOM   8609 O O   . GLY D 1 217 ? 126.003 100.948 121.867 1.00 60.13  ? 291 GLY D O   1 
ATOM   8610 N N   . PRO D 1 218 ? 125.439 98.851  121.289 1.00 59.13  ? 292 PRO D N   1 
ATOM   8611 C CA  . PRO D 1 218 ? 126.849 98.445  121.187 1.00 62.76  ? 292 PRO D CA  1 
ATOM   8612 C C   . PRO D 1 218 ? 127.602 99.128  120.060 1.00 61.35  ? 292 PRO D C   1 
ATOM   8613 O O   . PRO D 1 218 ? 128.840 99.122  120.075 1.00 61.39  ? 292 PRO D O   1 
ATOM   8614 C CB  . PRO D 1 218 ? 126.761 96.929  120.962 1.00 64.82  ? 292 PRO D CB  1 
ATOM   8615 C CG  . PRO D 1 218 ? 125.414 96.727  120.345 1.00 63.56  ? 292 PRO D CG  1 
ATOM   8616 C CD  . PRO D 1 218 ? 124.521 97.734  121.014 1.00 59.80  ? 292 PRO D CD  1 
ATOM   8617 N N   . SER D 1 219 ? 126.904 99.707  119.086 1.00 57.30  ? 293 SER D N   1 
ATOM   8618 C CA  . SER D 1 219 ? 127.569 100.352 117.962 1.00 56.02  ? 293 SER D CA  1 
ATOM   8619 C C   . SER D 1 219 ? 128.362 101.567 118.426 1.00 58.45  ? 293 SER D C   1 
ATOM   8620 O O   . SER D 1 219 ? 127.911 102.339 119.276 1.00 59.84  ? 293 SER D O   1 
ATOM   8621 C CB  . SER D 1 219 ? 126.544 100.768 116.908 1.00 56.97  ? 293 SER D CB  1 
ATOM   8622 O OG  . SER D 1 219 ? 127.129 101.615 115.935 1.00 57.52  ? 293 SER D OG  1 
ATOM   8623 N N   . SER D 1 220 ? 129.557 101.730 117.860 1.00 70.10  ? 294 SER D N   1 
ATOM   8624 C CA  . SER D 1 220 ? 130.425 102.859 118.164 1.00 71.47  ? 294 SER D CA  1 
ATOM   8625 C C   . SER D 1 220 ? 130.502 103.860 117.019 1.00 70.79  ? 294 SER D C   1 
ATOM   8626 O O   . SER D 1 220 ? 131.324 104.782 117.068 1.00 72.71  ? 294 SER D O   1 
ATOM   8627 C CB  . SER D 1 220 ? 131.828 102.365 118.524 1.00 70.83  ? 294 SER D CB  1 
ATOM   8628 O OG  . SER D 1 220 ? 131.795 101.515 119.658 1.00 71.16  ? 294 SER D OG  1 
ATOM   8629 N N   . TYR D 1 221 ? 129.671 103.704 115.994 1.00 70.59  ? 295 TYR D N   1 
ATOM   8630 C CA  . TYR D 1 221 ? 129.661 104.593 114.845 1.00 70.97  ? 295 TYR D CA  1 
ATOM   8631 C C   . TYR D 1 221 ? 128.487 105.563 114.943 1.00 69.27  ? 295 TYR D C   1 
ATOM   8632 O O   . TYR D 1 221 ? 127.699 105.539 115.891 1.00 66.18  ? 295 TYR D O   1 
ATOM   8633 C CB  . TYR D 1 221 ? 129.599 103.786 113.546 1.00 70.69  ? 295 TYR D CB  1 
ATOM   8634 C CG  . TYR D 1 221 ? 130.832 102.955 113.278 1.00 75.03  ? 295 TYR D CG  1 
ATOM   8635 C CD1 . TYR D 1 221 ? 131.973 103.527 112.732 1.00 71.79  ? 295 TYR D CD1 1 
ATOM   8636 C CD2 . TYR D 1 221 ? 130.854 101.598 113.570 1.00 73.82  ? 295 TYR D CD2 1 
ATOM   8637 C CE1 . TYR D 1 221 ? 133.103 102.771 112.485 1.00 70.68  ? 295 TYR D CE1 1 
ATOM   8638 C CE2 . TYR D 1 221 ? 131.980 100.833 113.326 1.00 73.95  ? 295 TYR D CE2 1 
ATOM   8639 C CZ  . TYR D 1 221 ? 133.101 101.425 112.783 1.00 73.64  ? 295 TYR D CZ  1 
ATOM   8640 O OH  . TYR D 1 221 ? 134.223 100.667 112.539 1.00 70.81  ? 295 TYR D OH  1 
ATOM   8641 N N   . LEU D 1 222 ? 128.374 106.432 113.943 1.00 62.10  ? 296 LEU D N   1 
ATOM   8642 C CA  . LEU D 1 222 ? 127.266 107.373 113.890 1.00 59.78  ? 296 LEU D CA  1 
ATOM   8643 C C   . LEU D 1 222 ? 125.950 106.642 113.656 1.00 58.22  ? 296 LEU D C   1 
ATOM   8644 O O   . LEU D 1 222 ? 125.907 105.560 113.065 1.00 60.93  ? 296 LEU D O   1 
ATOM   8645 C CB  . LEU D 1 222 ? 127.490 108.403 112.783 1.00 59.31  ? 296 LEU D CB  1 
ATOM   8646 C CG  . LEU D 1 222 ? 128.778 109.219 112.866 1.00 57.52  ? 296 LEU D CG  1 
ATOM   8647 C CD1 . LEU D 1 222 ? 128.845 110.238 111.743 1.00 57.48  ? 296 LEU D CD1 1 
ATOM   8648 C CD2 . LEU D 1 222 ? 128.858 109.908 114.208 1.00 53.57  ? 296 LEU D CD2 1 
ATOM   8649 N N   . SER D 1 223 ? 124.868 107.247 114.133 1.00 52.84  ? 297 SER D N   1 
ATOM   8650 C CA  . SER D 1 223 ? 123.519 106.738 113.932 1.00 51.77  ? 297 SER D CA  1 
ATOM   8651 C C   . SER D 1 223 ? 122.757 107.703 113.036 1.00 56.48  ? 297 SER D C   1 
ATOM   8652 O O   . SER D 1 223 ? 122.691 108.901 113.330 1.00 55.00  ? 297 SER D O   1 
ATOM   8653 C CB  . SER D 1 223 ? 122.794 106.561 115.267 1.00 52.94  ? 297 SER D CB  1 
ATOM   8654 O OG  . SER D 1 223 ? 121.388 106.563 115.089 1.00 57.87  ? 297 SER D OG  1 
ATOM   8655 N N   . ASN D 1 224 ? 122.199 107.180 111.945 1.00 55.07  ? 298 ASN D N   1 
ATOM   8656 C CA  . ASN D 1 224 ? 121.434 107.959 110.977 1.00 48.75  ? 298 ASN D CA  1 
ATOM   8657 C C   . ASN D 1 224 ? 119.963 107.599 111.132 1.00 49.65  ? 298 ASN D C   1 
ATOM   8658 O O   . ASN D 1 224 ? 119.558 106.476 110.814 1.00 51.46  ? 298 ASN D O   1 
ATOM   8659 C CB  . ASN D 1 224 ? 121.914 107.687 109.553 1.00 47.62  ? 298 ASN D CB  1 
ATOM   8660 C CG  . ASN D 1 224 ? 123.345 108.124 109.326 1.00 54.61  ? 298 ASN D CG  1 
ATOM   8661 O OD1 . ASN D 1 224 ? 123.658 109.312 109.376 1.00 53.30  ? 298 ASN D OD1 1 
ATOM   8662 N ND2 . ASN D 1 224 ? 124.226 107.162 109.075 1.00 56.60  ? 298 ASN D ND2 1 
ATOM   8663 N N   . VAL D 1 225 ? 119.165 108.548 111.617 1.00 40.84  ? 299 VAL D N   1 
ATOM   8664 C CA  . VAL D 1 225 ? 117.745 108.322 111.865 1.00 33.28  ? 299 VAL D CA  1 
ATOM   8665 C C   . VAL D 1 225 ? 116.942 109.425 111.192 1.00 37.14  ? 299 VAL D C   1 
ATOM   8666 O O   . VAL D 1 225 ? 117.187 110.611 111.434 1.00 40.43  ? 299 VAL D O   1 
ATOM   8667 C CB  . VAL D 1 225 ? 117.431 108.267 113.373 1.00 35.35  ? 299 VAL D CB  1 
ATOM   8668 C CG1 . VAL D 1 225 ? 115.938 108.170 113.598 1.00 40.49  ? 299 VAL D CG1 1 
ATOM   8669 C CG2 . VAL D 1 225 ? 118.148 107.096 114.023 1.00 39.66  ? 299 VAL D CG2 1 
ATOM   8670 N N   . ASP D 1 226 ? 115.975 109.038 110.364 1.00 43.94  ? 300 ASP D N   1 
ATOM   8671 C CA  . ASP D 1 226 ? 115.113 109.990 109.677 1.00 37.72  ? 300 ASP D CA  1 
ATOM   8672 C C   . ASP D 1 226 ? 113.889 110.273 110.538 1.00 38.34  ? 300 ASP D C   1 
ATOM   8673 O O   . ASP D 1 226 ? 113.259 109.339 111.051 1.00 43.93  ? 300 ASP D O   1 
ATOM   8674 C CB  . ASP D 1 226 ? 114.676 109.441 108.319 1.00 42.30  ? 300 ASP D CB  1 
ATOM   8675 C CG  . ASP D 1 226 ? 115.687 109.710 107.226 1.00 50.50  ? 300 ASP D CG  1 
ATOM   8676 O OD1 . ASP D 1 226 ? 116.879 109.881 107.549 1.00 53.01  ? 300 ASP D OD1 1 
ATOM   8677 O OD2 . ASP D 1 226 ? 115.289 109.751 106.043 1.00 52.04  ? 300 ASP D OD2 1 
ATOM   8678 N N   . VAL D 1 227 ? 113.547 111.553 110.697 1.00 32.49  ? 301 VAL D N   1 
ATOM   8679 C CA  . VAL D 1 227 ? 112.372 111.939 111.470 1.00 29.02  ? 301 VAL D CA  1 
ATOM   8680 C C   . VAL D 1 227 ? 111.411 112.698 110.563 1.00 32.64  ? 301 VAL D C   1 
ATOM   8681 O O   . VAL D 1 227 ? 111.818 113.602 109.824 1.00 39.48  ? 301 VAL D O   1 
ATOM   8682 C CB  . VAL D 1 227 ? 112.746 112.760 112.721 1.00 30.85  ? 301 VAL D CB  1 
ATOM   8683 C CG1 . VAL D 1 227 ? 113.450 114.041 112.351 1.00 36.16  ? 301 VAL D CG1 1 
ATOM   8684 C CG2 . VAL D 1 227 ? 111.507 113.053 113.553 1.00 35.94  ? 301 VAL D CG2 1 
ATOM   8685 N N   . TYR D 1 228 ? 110.143 112.297 110.597 1.00 29.48  ? 302 TYR D N   1 
ATOM   8686 C CA  . TYR D 1 228 ? 109.074 112.893 109.814 1.00 27.55  ? 302 TYR D CA  1 
ATOM   8687 C C   . TYR D 1 228 ? 108.093 113.572 110.759 1.00 31.35  ? 302 TYR D C   1 
ATOM   8688 O O   . TYR D 1 228 ? 107.806 113.052 111.842 1.00 37.13  ? 302 TYR D O   1 
ATOM   8689 C CB  . TYR D 1 228 ? 108.320 111.836 108.998 1.00 27.24  ? 302 TYR D CB  1 
ATOM   8690 C CG  . TYR D 1 228 ? 109.133 111.095 107.959 1.00 24.41  ? 302 TYR D CG  1 
ATOM   8691 C CD1 . TYR D 1 228 ? 110.402 111.521 107.595 1.00 36.75  ? 302 TYR D CD1 1 
ATOM   8692 C CD2 . TYR D 1 228 ? 108.621 109.966 107.336 1.00 31.12  ? 302 TYR D CD2 1 
ATOM   8693 C CE1 . TYR D 1 228 ? 111.138 110.840 106.646 1.00 35.73  ? 302 TYR D CE1 1 
ATOM   8694 C CE2 . TYR D 1 228 ? 109.348 109.280 106.385 1.00 31.44  ? 302 TYR D CE2 1 
ATOM   8695 C CZ  . TYR D 1 228 ? 110.605 109.722 106.043 1.00 30.78  ? 302 TYR D CZ  1 
ATOM   8696 O OH  . TYR D 1 228 ? 111.335 109.040 105.096 1.00 37.18  ? 302 TYR D OH  1 
ATOM   8697 N N   . LEU D 1 229 ? 107.569 114.723 110.352 1.00 34.48  ? 303 LEU D N   1 
ATOM   8698 C CA  . LEU D 1 229 ? 106.512 115.394 111.097 1.00 24.86  ? 303 LEU D CA  1 
ATOM   8699 C C   . LEU D 1 229 ? 105.329 115.581 110.160 1.00 29.29  ? 303 LEU D C   1 
ATOM   8700 O O   . LEU D 1 229 ? 105.440 116.284 109.150 1.00 41.24  ? 303 LEU D O   1 
ATOM   8701 C CB  . LEU D 1 229 ? 106.990 116.734 111.663 1.00 33.59  ? 303 LEU D CB  1 
ATOM   8702 C CG  . LEU D 1 229 ? 106.066 117.489 112.628 1.00 37.70  ? 303 LEU D CG  1 
ATOM   8703 C CD1 . LEU D 1 229 ? 106.895 118.370 113.551 1.00 35.86  ? 303 LEU D CD1 1 
ATOM   8704 C CD2 . LEU D 1 229 ? 105.006 118.318 111.919 1.00 40.91  ? 303 LEU D CD2 1 
ATOM   8705 N N   . ASP D 1 230 ? 104.203 114.952 110.500 1.00 34.91  ? 304 ASP D N   1 
ATOM   8706 C CA  . ASP D 1 230 ? 102.984 115.005 109.691 1.00 33.68  ? 304 ASP D CA  1 
ATOM   8707 C C   . ASP D 1 230 ? 103.234 114.511 108.268 1.00 35.38  ? 304 ASP D C   1 
ATOM   8708 O O   . ASP D 1 230 ? 102.720 115.068 107.297 1.00 42.83  ? 304 ASP D O   1 
ATOM   8709 C CB  . ASP D 1 230 ? 102.386 116.413 109.683 1.00 40.52  ? 304 ASP D CB  1 
ATOM   8710 C CG  . ASP D 1 230 ? 101.414 116.639 110.823 1.00 44.60  ? 304 ASP D CG  1 
ATOM   8711 O OD1 . ASP D 1 230 ? 100.796 115.656 111.283 1.00 45.96  ? 304 ASP D OD1 1 
ATOM   8712 O OD2 . ASP D 1 230 ? 101.265 117.800 111.259 1.00 43.55  ? 304 ASP D OD2 1 
ATOM   8713 N N   . GLY D 1 231 ? 104.031 113.451 108.143 1.00 35.68  ? 305 GLY D N   1 
ATOM   8714 C CA  . GLY D 1 231 ? 104.281 112.835 106.857 1.00 32.61  ? 305 GLY D CA  1 
ATOM   8715 C C   . GLY D 1 231 ? 105.325 113.512 106.000 1.00 27.93  ? 305 GLY D C   1 
ATOM   8716 O O   . GLY D 1 231 ? 105.518 113.099 104.851 1.00 38.53  ? 305 GLY D O   1 
ATOM   8717 N N   . HIS D 1 232 ? 106.007 114.531 106.514 1.00 29.90  ? 306 HIS D N   1 
ATOM   8718 C CA  . HIS D 1 232 ? 107.008 115.272 105.760 1.00 29.22  ? 306 HIS D CA  1 
ATOM   8719 C C   . HIS D 1 232 ? 108.360 115.112 106.437 1.00 34.25  ? 306 HIS D C   1 
ATOM   8720 O O   . HIS D 1 232 ? 108.464 115.245 107.660 1.00 40.62  ? 306 HIS D O   1 
ATOM   8721 C CB  . HIS D 1 232 ? 106.637 116.754 105.665 1.00 35.86  ? 306 HIS D CB  1 
ATOM   8722 C CG  . HIS D 1 232 ? 105.531 117.040 104.698 1.00 41.07  ? 306 HIS D CG  1 
ATOM   8723 N ND1 . HIS D 1 232 ? 104.750 118.173 104.775 1.00 38.45  ? 306 HIS D ND1 1 
ATOM   8724 C CD2 . HIS D 1 232 ? 105.072 116.338 103.635 1.00 42.83  ? 306 HIS D CD2 1 
ATOM   8725 C CE1 . HIS D 1 232 ? 103.859 118.158 103.801 1.00 39.46  ? 306 HIS D CE1 1 
ATOM   8726 N NE2 . HIS D 1 232 ? 104.033 117.056 103.094 1.00 43.74  ? 306 HIS D NE2 1 
ATOM   8727 N N   . LEU D 1 233 ? 109.390 114.833 105.643 1.00 30.12  ? 307 LEU D N   1 
ATOM   8728 C CA  . LEU D 1 233 ? 110.733 114.676 106.185 1.00 22.92  ? 307 LEU D CA  1 
ATOM   8729 C C   . LEU D 1 233 ? 111.263 116.034 106.621 1.00 28.12  ? 307 LEU D C   1 
ATOM   8730 O O   . LEU D 1 233 ? 111.437 116.934 105.794 1.00 44.08  ? 307 LEU D O   1 
ATOM   8731 C CB  . LEU D 1 233 ? 111.654 114.038 105.145 1.00 30.78  ? 307 LEU D CB  1 
ATOM   8732 C CG  . LEU D 1 233 ? 113.073 113.612 105.542 1.00 33.21  ? 307 LEU D CG  1 
ATOM   8733 C CD1 . LEU D 1 233 ? 113.539 112.477 104.647 1.00 31.92  ? 307 LEU D CD1 1 
ATOM   8734 C CD2 . LEU D 1 233 ? 114.065 114.765 105.464 1.00 37.70  ? 307 LEU D CD2 1 
ATOM   8735 N N   . ILE D 1 234 ? 111.524 116.183 107.916 1.00 29.90  ? 308 ILE D N   1 
ATOM   8736 C CA  . ILE D 1 234 ? 112.021 117.437 108.459 1.00 33.94  ? 308 ILE D CA  1 
ATOM   8737 C C   . ILE D 1 234 ? 113.536 117.420 108.623 1.00 39.31  ? 308 ILE D C   1 
ATOM   8738 O O   . ILE D 1 234 ? 114.189 118.437 108.382 1.00 42.17  ? 308 ILE D O   1 
ATOM   8739 C CB  . ILE D 1 234 ? 111.307 117.782 109.785 1.00 32.18  ? 308 ILE D CB  1 
ATOM   8740 C CG1 . ILE D 1 234 ? 111.776 116.881 110.929 1.00 38.78  ? 308 ILE D CG1 1 
ATOM   8741 C CG2 . ILE D 1 234 ? 109.801 117.698 109.611 1.00 40.01  ? 308 ILE D CG2 1 
ATOM   8742 C CD1 . ILE D 1 234 ? 111.034 117.104 112.228 1.00 38.85  ? 308 ILE D CD1 1 
ATOM   8743 N N   . THR D 1 235 ? 114.117 116.282 109.003 1.00 36.51  ? 309 THR D N   1 
ATOM   8744 C CA  . THR D 1 235 ? 115.569 116.172 109.082 1.00 35.73  ? 309 THR D CA  1 
ATOM   8745 C C   . THR D 1 235 ? 115.974 114.717 109.290 1.00 33.35  ? 309 THR D C   1 
ATOM   8746 O O   . THR D 1 235 ? 115.146 113.836 109.560 1.00 43.56  ? 309 THR D O   1 
ATOM   8747 C CB  . THR D 1 235 ? 116.159 117.047 110.196 1.00 43.98  ? 309 THR D CB  1 
ATOM   8748 O OG1 . THR D 1 235 ? 117.587 117.066 110.082 1.00 51.88  ? 309 THR D OG1 1 
ATOM   8749 C CG2 . THR D 1 235 ? 115.783 116.515 111.562 1.00 38.06  ? 309 THR D CG2 1 
ATOM   8750 N N   . THR D 1 236 ? 117.275 114.486 109.130 1.00 33.58  ? 310 THR D N   1 
ATOM   8751 C CA  . THR D 1 236 ? 117.933 113.227 109.444 1.00 39.81  ? 310 THR D CA  1 
ATOM   8752 C C   . THR D 1 236 ? 119.011 113.517 110.476 1.00 38.91  ? 310 THR D C   1 
ATOM   8753 O O   . THR D 1 236 ? 119.939 114.287 110.209 1.00 41.84  ? 310 THR D O   1 
ATOM   8754 C CB  . THR D 1 236 ? 118.549 112.596 108.194 1.00 41.71  ? 310 THR D CB  1 
ATOM   8755 O OG1 . THR D 1 236 ? 117.510 112.089 107.348 1.00 47.98  ? 310 THR D OG1 1 
ATOM   8756 C CG2 . THR D 1 236 ? 119.490 111.463 108.575 1.00 39.60  ? 310 THR D CG2 1 
ATOM   8757 N N   . VAL D 1 237 ? 118.889 112.908 111.647 1.00 43.10  ? 311 VAL D N   1 
ATOM   8758 C CA  . VAL D 1 237 ? 119.858 113.093 112.717 1.00 39.74  ? 311 VAL D CA  1 
ATOM   8759 C C   . VAL D 1 237 ? 121.005 112.113 112.514 1.00 45.02  ? 311 VAL D C   1 
ATOM   8760 O O   . VAL D 1 237 ? 120.787 110.928 112.224 1.00 50.17  ? 311 VAL D O   1 
ATOM   8761 C CB  . VAL D 1 237 ? 119.201 112.920 114.097 1.00 41.95  ? 311 VAL D CB  1 
ATOM   8762 C CG1 . VAL D 1 237 ? 118.125 113.975 114.293 1.00 44.82  ? 311 VAL D CG1 1 
ATOM   8763 C CG2 . VAL D 1 237 ? 118.605 111.535 114.247 1.00 44.02  ? 311 VAL D CG2 1 
ATOM   8764 N N   . GLN D 1 238 ? 122.228 112.621 112.632 1.00 48.09  ? 312 GLN D N   1 
ATOM   8765 C CA  . GLN D 1 238 ? 123.453 111.858 112.414 1.00 47.54  ? 312 GLN D CA  1 
ATOM   8766 C C   . GLN D 1 238 ? 124.303 112.007 113.670 1.00 48.69  ? 312 GLN D C   1 
ATOM   8767 O O   . GLN D 1 238 ? 125.127 112.919 113.778 1.00 52.05  ? 312 GLN D O   1 
ATOM   8768 C CB  . GLN D 1 238 ? 124.187 112.344 111.166 1.00 48.69  ? 312 GLN D CB  1 
ATOM   8769 C CG  . GLN D 1 238 ? 125.429 111.545 110.815 1.00 53.51  ? 312 GLN D CG  1 
ATOM   8770 C CD  . GLN D 1 238 ? 126.086 112.031 109.538 1.00 58.52  ? 312 GLN D CD  1 
ATOM   8771 O OE1 . GLN D 1 238 ? 125.634 112.998 108.924 1.00 58.17  ? 312 GLN D OE1 1 
ATOM   8772 N NE2 . GLN D 1 238 ? 127.155 111.359 109.128 1.00 58.30  ? 312 GLN D NE2 1 
ATOM   8773 N N   . GLY D 1 239 ? 124.092 111.106 114.622 1.00 50.10  ? 313 GLY D N   1 
ATOM   8774 C CA  . GLY D 1 239 ? 124.822 111.143 115.873 1.00 45.37  ? 313 GLY D CA  1 
ATOM   8775 C C   . GLY D 1 239 ? 124.421 110.031 116.817 1.00 46.68  ? 313 GLY D C   1 
ATOM   8776 O O   . GLY D 1 239 ? 124.126 108.916 116.378 1.00 55.33  ? 313 GLY D O   1 
ATOM   8777 N N   . ASP D 1 240 ? 124.404 110.317 118.120 1.00 39.28  ? 314 ASP D N   1 
ATOM   8778 C CA  . ASP D 1 240 ? 124.045 109.280 119.081 1.00 37.97  ? 314 ASP D CA  1 
ATOM   8779 C C   . ASP D 1 240 ? 122.550 108.986 119.050 1.00 38.03  ? 314 ASP D C   1 
ATOM   8780 O O   . ASP D 1 240 ? 122.148 107.819 119.077 1.00 46.20  ? 314 ASP D O   1 
ATOM   8781 C CB  . ASP D 1 240 ? 124.492 109.681 120.485 1.00 41.46  ? 314 ASP D CB  1 
ATOM   8782 C CG  . ASP D 1 240 ? 125.998 109.772 120.613 1.00 45.00  ? 314 ASP D CG  1 
ATOM   8783 O OD1 . ASP D 1 240 ? 126.688 109.725 119.574 1.00 47.15  ? 314 ASP D OD1 1 
ATOM   8784 O OD2 . ASP D 1 240 ? 126.494 109.890 121.753 1.00 47.46  ? 314 ASP D OD2 1 
ATOM   8785 N N   . GLY D 1 241 ? 121.713 110.015 118.977 1.00 30.89  ? 315 GLY D N   1 
ATOM   8786 C CA  . GLY D 1 241 ? 120.287 109.784 118.876 1.00 30.85  ? 315 GLY D CA  1 
ATOM   8787 C C   . GLY D 1 241 ? 119.484 111.033 119.187 1.00 31.97  ? 315 GLY D C   1 
ATOM   8788 O O   . GLY D 1 241 ? 120.013 112.146 119.219 1.00 39.58  ? 315 GLY D O   1 
ATOM   8789 N N   . VAL D 1 242 ? 118.186 110.815 119.414 1.00 30.16  ? 316 VAL D N   1 
ATOM   8790 C CA  . VAL D 1 242 ? 117.220 111.878 119.663 1.00 29.80  ? 316 VAL D CA  1 
ATOM   8791 C C   . VAL D 1 242 ? 116.551 111.649 121.013 1.00 35.06  ? 316 VAL D C   1 
ATOM   8792 O O   . VAL D 1 242 ? 116.462 110.523 121.510 1.00 41.86  ? 316 VAL D O   1 
ATOM   8793 C CB  . VAL D 1 242 ? 116.160 111.975 118.547 1.00 27.90  ? 316 VAL D CB  1 
ATOM   8794 C CG1 . VAL D 1 242 ? 116.806 112.357 117.239 1.00 26.98  ? 316 VAL D CG1 1 
ATOM   8795 C CG2 . VAL D 1 242 ? 115.412 110.659 118.409 1.00 36.92  ? 316 VAL D CG2 1 
ATOM   8796 N N   . ILE D 1 243 ? 116.076 112.745 121.607 1.00 34.70  ? 317 ILE D N   1 
ATOM   8797 C CA  . ILE D 1 243 ? 115.504 112.720 122.950 1.00 24.86  ? 317 ILE D CA  1 
ATOM   8798 C C   . ILE D 1 243 ? 114.083 113.279 122.887 1.00 32.40  ? 317 ILE D C   1 
ATOM   8799 O O   . ILE D 1 243 ? 113.673 114.057 123.756 1.00 46.69  ? 317 ILE D O   1 
ATOM   8800 C CB  . ILE D 1 243 ? 116.377 113.501 123.950 1.00 26.36  ? 317 ILE D CB  1 
ATOM   8801 C CG1 . ILE D 1 243 ? 117.772 112.909 124.011 1.00 26.94  ? 317 ILE D CG1 1 
ATOM   8802 C CG2 . ILE D 1 243 ? 115.891 113.291 125.374 1.00 33.34  ? 317 ILE D CG2 1 
ATOM   8803 C CD1 . ILE D 1 243 ? 118.744 113.782 124.767 1.00 35.88  ? 317 ILE D CD1 1 
ATOM   8804 N N   . VAL D 1 244 ? 113.352 112.972 121.814 1.00 24.31  ? 318 VAL D N   1 
ATOM   8805 C CA  . VAL D 1 244 ? 111.977 113.450 121.674 1.00 28.75  ? 318 VAL D CA  1 
ATOM   8806 C C   . VAL D 1 244 ? 111.206 113.189 122.965 1.00 27.98  ? 318 VAL D C   1 
ATOM   8807 O O   . VAL D 1 244 ? 111.103 112.048 123.428 1.00 34.27  ? 318 VAL D O   1 
ATOM   8808 C CB  . VAL D 1 244 ? 111.287 112.813 120.453 1.00 26.42  ? 318 VAL D CB  1 
ATOM   8809 C CG1 . VAL D 1 244 ? 111.375 111.298 120.501 1.00 30.48  ? 318 VAL D CG1 1 
ATOM   8810 C CG2 . VAL D 1 244 ? 109.835 113.248 120.390 1.00 29.39  ? 318 VAL D CG2 1 
ATOM   8811 N N   . SER D 1 245 ? 110.674 114.256 123.566 1.00 27.96  ? 319 SER D N   1 
ATOM   8812 C CA  . SER D 1 245 ? 110.269 114.229 124.965 1.00 19.75  ? 319 SER D CA  1 
ATOM   8813 C C   . SER D 1 245 ? 108.995 115.037 125.171 1.00 28.30  ? 319 SER D C   1 
ATOM   8814 O O   . SER D 1 245 ? 108.401 115.569 124.229 1.00 34.56  ? 319 SER D O   1 
ATOM   8815 C CB  . SER D 1 245 ? 111.381 114.776 125.869 1.00 27.90  ? 319 SER D CB  1 
ATOM   8816 O OG  . SER D 1 245 ? 111.476 116.184 125.771 1.00 36.55  ? 319 SER D OG  1 
ATOM   8817 N N   . THR D 1 246 ? 108.588 115.117 126.429 1.00 28.10  ? 320 THR D N   1 
ATOM   8818 C CA  . THR D 1 246 ? 107.469 115.895 126.926 1.00 23.80  ? 320 THR D CA  1 
ATOM   8819 C C   . THR D 1 246 ? 107.978 117.076 127.745 1.00 29.21  ? 320 THR D C   1 
ATOM   8820 O O   . THR D 1 246 ? 109.161 117.138 128.098 1.00 36.48  ? 320 THR D O   1 
ATOM   8821 C CB  . THR D 1 246 ? 106.563 115.015 127.794 1.00 23.03  ? 320 THR D CB  1 
ATOM   8822 O OG1 . THR D 1 246 ? 107.142 114.881 129.095 1.00 28.87  ? 320 THR D OG1 1 
ATOM   8823 C CG2 . THR D 1 246 ? 106.415 113.641 127.187 1.00 28.53  ? 320 THR D CG2 1 
ATOM   8824 N N   . PRO D 1 247 ? 107.113 118.052 128.050 1.00 22.81  ? 321 PRO D N   1 
ATOM   8825 C CA  . PRO D 1 247 ? 107.554 119.147 128.931 1.00 13.77  ? 321 PRO D CA  1 
ATOM   8826 C C   . PRO D 1 247 ? 108.074 118.678 130.280 1.00 26.80  ? 321 PRO D C   1 
ATOM   8827 O O   . PRO D 1 247 ? 109.094 119.195 130.754 1.00 28.16  ? 321 PRO D O   1 
ATOM   8828 C CB  . PRO D 1 247 ? 106.289 120.002 129.071 1.00 14.79  ? 321 PRO D CB  1 
ATOM   8829 C CG  . PRO D 1 247 ? 105.559 119.774 127.805 1.00 20.91  ? 321 PRO D CG  1 
ATOM   8830 C CD  . PRO D 1 247 ? 105.798 118.334 127.448 1.00 26.30  ? 321 PRO D CD  1 
ATOM   8831 N N   . THR D 1 248 ? 107.424 117.691 130.904 1.00 33.28  ? 322 THR D N   1 
ATOM   8832 C CA  . THR D 1 248 ? 107.896 117.212 132.199 1.00 29.03  ? 322 THR D CA  1 
ATOM   8833 C C   . THR D 1 248 ? 109.199 116.434 132.079 1.00 28.80  ? 322 THR D C   1 
ATOM   8834 O O   . THR D 1 248 ? 109.851 116.179 133.097 1.00 39.79  ? 322 THR D O   1 
ATOM   8835 C CB  . THR D 1 248 ? 106.831 116.350 132.882 1.00 28.18  ? 322 THR D CB  1 
ATOM   8836 O OG1 . THR D 1 248 ? 107.235 116.071 134.228 1.00 39.93  ? 322 THR D OG1 1 
ATOM   8837 C CG2 . THR D 1 248 ? 106.644 115.038 132.149 1.00 29.19  ? 322 THR D CG2 1 
ATOM   8838 N N   . GLY D 1 249 ? 109.586 116.051 130.868 1.00 22.95  ? 323 GLY D N   1 
ATOM   8839 C CA  . GLY D 1 249 ? 110.887 115.487 130.592 1.00 19.97  ? 323 GLY D CA  1 
ATOM   8840 C C   . GLY D 1 249 ? 111.890 116.484 130.061 1.00 24.63  ? 323 GLY D C   1 
ATOM   8841 O O   . GLY D 1 249 ? 112.982 116.085 129.644 1.00 30.43  ? 323 GLY D O   1 
ATOM   8842 N N   . SER D 1 250 ? 111.548 117.776 130.055 1.00 32.16  ? 324 SER D N   1 
ATOM   8843 C CA  . SER D 1 250 ? 112.477 118.788 129.564 1.00 26.67  ? 324 SER D CA  1 
ATOM   8844 C C   . SER D 1 250 ? 113.708 118.887 130.456 1.00 31.55  ? 324 SER D C   1 
ATOM   8845 O O   . SER D 1 250 ? 114.822 119.102 129.966 1.00 39.55  ? 324 SER D O   1 
ATOM   8846 C CB  . SER D 1 250 ? 111.774 120.142 129.468 1.00 32.38  ? 324 SER D CB  1 
ATOM   8847 O OG  . SER D 1 250 ? 111.323 120.572 130.740 1.00 34.98  ? 324 SER D OG  1 
ATOM   8848 N N   . THR D 1 251 ? 113.526 118.736 131.765 1.00 37.46  ? 325 THR D N   1 
ATOM   8849 C CA  . THR D 1 251 ? 114.623 118.765 132.723 1.00 36.28  ? 325 THR D CA  1 
ATOM   8850 C C   . THR D 1 251 ? 115.297 117.410 132.885 1.00 33.77  ? 325 THR D C   1 
ATOM   8851 O O   . THR D 1 251 ? 116.258 117.294 133.651 1.00 38.77  ? 325 THR D O   1 
ATOM   8852 C CB  . THR D 1 251 ? 114.120 119.260 134.080 1.00 32.70  ? 325 THR D CB  1 
ATOM   8853 O OG1 . THR D 1 251 ? 113.194 118.311 134.620 1.00 38.92  ? 325 THR D OG1 1 
ATOM   8854 C CG2 . THR D 1 251 ? 113.425 120.603 133.927 1.00 33.19  ? 325 THR D CG2 1 
ATOM   8855 N N   . ALA D 1 252 ? 114.810 116.391 132.181 1.00 37.41  ? 326 ALA D N   1 
ATOM   8856 C CA  . ALA D 1 252 ? 115.400 115.059 132.162 1.00 34.51  ? 326 ALA D CA  1 
ATOM   8857 C C   . ALA D 1 252 ? 116.564 115.010 131.181 1.00 36.03  ? 326 ALA D C   1 
ATOM   8858 O O   . ALA D 1 252 ? 117.128 116.049 130.827 1.00 42.31  ? 326 ALA D O   1 
ATOM   8859 C CB  . ALA D 1 252 ? 114.351 114.006 131.801 1.00 38.12  ? 326 ALA D CB  1 
ATOM   8860 N N   . TYR D 1 253 ? 116.939 113.799 130.767 1.00 29.62  ? 327 TYR D N   1 
ATOM   8861 C CA  . TYR D 1 253 ? 118.018 113.532 129.819 1.00 24.97  ? 327 TYR D CA  1 
ATOM   8862 C C   . TYR D 1 253 ? 118.033 114.507 128.645 1.00 31.35  ? 327 TYR D C   1 
ATOM   8863 O O   . TYR D 1 253 ? 119.090 114.752 128.055 1.00 42.95  ? 327 TYR D O   1 
ATOM   8864 C CB  . TYR D 1 253 ? 117.890 112.086 129.329 1.00 32.63  ? 327 TYR D CB  1 
ATOM   8865 C CG  . TYR D 1 253 ? 118.930 111.614 128.340 1.00 33.58  ? 327 TYR D CG  1 
ATOM   8866 C CD1 . TYR D 1 253 ? 120.269 111.542 128.691 1.00 40.76  ? 327 TYR D CD1 1 
ATOM   8867 C CD2 . TYR D 1 253 ? 118.560 111.161 127.083 1.00 35.00  ? 327 TYR D CD2 1 
ATOM   8868 C CE1 . TYR D 1 253 ? 121.218 111.087 127.800 1.00 35.79  ? 327 TYR D CE1 1 
ATOM   8869 C CE2 . TYR D 1 253 ? 119.502 110.699 126.186 1.00 35.63  ? 327 TYR D CE2 1 
ATOM   8870 C CZ  . TYR D 1 253 ? 120.830 110.666 126.550 1.00 35.42  ? 327 TYR D CZ  1 
ATOM   8871 O OH  . TYR D 1 253 ? 121.773 110.208 125.661 1.00 41.63  ? 327 TYR D OH  1 
ATOM   8872 N N   . ALA D 1 254 ? 116.870 115.059 128.292 1.00 33.74  ? 328 ALA D N   1 
ATOM   8873 C CA  . ALA D 1 254 ? 116.831 116.132 127.302 1.00 29.75  ? 328 ALA D CA  1 
ATOM   8874 C C   . ALA D 1 254 ? 117.627 117.346 127.766 1.00 33.74  ? 328 ALA D C   1 
ATOM   8875 O O   . ALA D 1 254 ? 118.356 117.957 126.975 1.00 39.17  ? 328 ALA D O   1 
ATOM   8876 C CB  . ALA D 1 254 ? 115.383 116.522 127.007 1.00 35.53  ? 328 ALA D CB  1 
ATOM   8877 N N   . ALA D 1 255 ? 117.501 117.714 129.045 1.00 32.42  ? 329 ALA D N   1 
ATOM   8878 C CA  . ALA D 1 255 ? 118.251 118.853 129.565 1.00 26.93  ? 329 ALA D CA  1 
ATOM   8879 C C   . ALA D 1 255 ? 119.750 118.601 129.534 1.00 33.99  ? 329 ALA D C   1 
ATOM   8880 O O   . ALA D 1 255 ? 120.536 119.544 129.387 1.00 41.85  ? 329 ALA D O   1 
ATOM   8881 C CB  . ALA D 1 255 ? 117.810 119.175 130.992 1.00 32.33  ? 329 ALA D CB  1 
ATOM   8882 N N   . ALA D 1 256 ? 120.165 117.341 129.678 1.00 33.92  ? 330 ALA D N   1 
ATOM   8883 C CA  . ALA D 1 256 ? 121.587 117.024 129.646 1.00 26.57  ? 330 ALA D CA  1 
ATOM   8884 C C   . ALA D 1 256 ? 122.194 117.309 128.280 1.00 30.56  ? 330 ALA D C   1 
ATOM   8885 O O   . ALA D 1 256 ? 123.364 117.695 128.189 1.00 37.51  ? 330 ALA D O   1 
ATOM   8886 C CB  . ALA D 1 256 ? 121.804 115.562 130.031 1.00 30.54  ? 330 ALA D CB  1 
ATOM   8887 N N   . ALA D 1 257 ? 121.417 117.142 127.214 1.00 29.37  ? 331 ALA D N   1 
ATOM   8888 C CA  . ALA D 1 257 ? 121.903 117.342 125.857 1.00 29.44  ? 331 ALA D CA  1 
ATOM   8889 C C   . ALA D 1 257 ? 121.788 118.785 125.381 1.00 30.87  ? 331 ALA D C   1 
ATOM   8890 O O   . ALA D 1 257 ? 122.185 119.079 124.249 1.00 36.21  ? 331 ALA D O   1 
ATOM   8891 C CB  . ALA D 1 257 ? 121.151 116.425 124.891 1.00 32.43  ? 331 ALA D CB  1 
ATOM   8892 N N   . GLY D 1 258 ? 121.261 119.686 126.204 1.00 27.85  ? 332 GLY D N   1 
ATOM   8893 C CA  . GLY D 1 258 ? 121.169 121.086 125.850 1.00 26.02  ? 332 GLY D CA  1 
ATOM   8894 C C   . GLY D 1 258 ? 119.774 121.626 125.617 1.00 30.40  ? 332 GLY D C   1 
ATOM   8895 O O   . GLY D 1 258 ? 119.645 122.751 125.120 1.00 32.91  ? 332 GLY D O   1 
ATOM   8896 N N   . ALA D 1 259 ? 118.730 120.875 125.954 1.00 31.64  ? 333 ALA D N   1 
ATOM   8897 C CA  . ALA D 1 259 ? 117.374 121.367 125.776 1.00 24.91  ? 333 ALA D CA  1 
ATOM   8898 C C   . ALA D 1 259 ? 117.049 122.438 126.814 1.00 32.13  ? 333 ALA D C   1 
ATOM   8899 O O   . ALA D 1 259 ? 117.642 122.501 127.894 1.00 38.80  ? 333 ALA D O   1 
ATOM   8900 C CB  . ALA D 1 259 ? 116.367 120.221 125.870 1.00 34.91  ? 333 ALA D CB  1 
ATOM   8901 N N   . SER D 1 260 ? 116.088 123.290 126.469 1.00 30.76  ? 334 SER D N   1 
ATOM   8902 C CA  . SER D 1 260 ? 115.667 124.364 127.353 1.00 25.56  ? 334 SER D CA  1 
ATOM   8903 C C   . SER D 1 260 ? 114.733 123.833 128.438 1.00 31.24  ? 334 SER D C   1 
ATOM   8904 O O   . SER D 1 260 ? 114.258 122.695 128.391 1.00 33.88  ? 334 SER D O   1 
ATOM   8905 C CB  . SER D 1 260 ? 114.981 125.473 126.557 1.00 26.66  ? 334 SER D CB  1 
ATOM   8906 O OG  . SER D 1 260 ? 115.880 126.082 125.648 1.00 40.03  ? 334 SER D OG  1 
ATOM   8907 N N   . MET D 1 261 ? 114.471 124.680 129.429 1.00 34.90  ? 335 MET D N   1 
ATOM   8908 C CA  . MET D 1 261 ? 113.574 124.340 130.525 1.00 26.76  ? 335 MET D CA  1 
ATOM   8909 C C   . MET D 1 261 ? 112.152 124.711 130.122 1.00 30.85  ? 335 MET D C   1 
ATOM   8910 O O   . MET D 1 261 ? 111.874 125.874 129.814 1.00 33.91  ? 335 MET D O   1 
ATOM   8911 C CB  . MET D 1 261 ? 113.980 125.070 131.804 1.00 33.71  ? 335 MET D CB  1 
ATOM   8912 C CG  . MET D 1 261 ? 115.452 124.934 132.228 1.00 33.84  ? 335 MET D CG  1 
ATOM   8913 S SD  . MET D 1 261 ? 116.023 123.331 132.846 1.00 47.20  ? 335 MET D SD  1 
ATOM   8914 C CE  . MET D 1 261 ? 116.240 122.374 131.350 1.00 34.68  ? 335 MET D CE  1 
ATOM   8915 N N   . ILE D 1 262 ? 111.257 123.728 130.119 1.00 36.45  ? 336 ILE D N   1 
ATOM   8916 C CA  . ILE D 1 262 ? 109.884 123.916 129.667 1.00 31.49  ? 336 ILE D CA  1 
ATOM   8917 C C   . ILE D 1 262 ? 108.931 123.532 130.789 1.00 30.09  ? 336 ILE D C   1 
ATOM   8918 O O   . ILE D 1 262 ? 108.997 122.415 131.315 1.00 36.64  ? 336 ILE D O   1 
ATOM   8919 C CB  . ILE D 1 262 ? 109.596 123.110 128.387 1.00 24.08  ? 336 ILE D CB  1 
ATOM   8920 C CG1 . ILE D 1 262 ? 110.329 123.734 127.199 1.00 31.70  ? 336 ILE D CG1 1 
ATOM   8921 C CG2 . ILE D 1 262 ? 108.116 123.029 128.126 1.00 25.88  ? 336 ILE D CG2 1 
ATOM   8922 C CD1 . ILE D 1 262 ? 110.211 122.944 125.927 1.00 34.50  ? 336 ILE D CD1 1 
ATOM   8923 N N   . HIS D 1 263 ? 108.054 124.463 131.152 1.00 25.39  ? 337 HIS D N   1 
ATOM   8924 C CA  . HIS D 1 263 ? 107.098 124.227 132.222 1.00 18.58  ? 337 HIS D CA  1 
ATOM   8925 C C   . HIS D 1 263 ? 106.060 123.197 131.778 1.00 28.18  ? 337 HIS D C   1 
ATOM   8926 O O   . HIS D 1 263 ? 105.649 123.190 130.614 1.00 38.57  ? 337 HIS D O   1 
ATOM   8927 C CB  . HIS D 1 263 ? 106.418 125.541 132.610 1.00 22.62  ? 337 HIS D CB  1 
ATOM   8928 C CG  . HIS D 1 263 ? 105.745 125.509 133.947 1.00 23.78  ? 337 HIS D CG  1 
ATOM   8929 N ND1 . HIS D 1 263 ? 104.574 124.821 134.179 1.00 30.59  ? 337 HIS D ND1 1 
ATOM   8930 C CD2 . HIS D 1 263 ? 106.082 126.085 135.125 1.00 23.04  ? 337 HIS D CD2 1 
ATOM   8931 C CE1 . HIS D 1 263 ? 104.221 124.971 135.443 1.00 27.66  ? 337 HIS D CE1 1 
ATOM   8932 N NE2 . HIS D 1 263 ? 105.118 125.735 136.038 1.00 29.41  ? 337 HIS D NE2 1 
ATOM   8933 N N   . PRO D 1 264 ? 105.618 122.314 132.679 1.00 25.08  ? 338 PRO D N   1 
ATOM   8934 C CA  . PRO D 1 264 ? 104.666 121.265 132.283 1.00 25.41  ? 338 PRO D CA  1 
ATOM   8935 C C   . PRO D 1 264 ? 103.259 121.759 131.974 1.00 24.44  ? 338 PRO D C   1 
ATOM   8936 O O   . PRO D 1 264 ? 102.369 120.943 131.716 1.00 34.06  ? 338 PRO D O   1 
ATOM   8937 C CB  . PRO D 1 264 ? 104.667 120.325 133.497 1.00 25.62  ? 338 PRO D CB  1 
ATOM   8938 C CG  . PRO D 1 264 ? 105.127 121.177 134.630 1.00 20.73  ? 338 PRO D CG  1 
ATOM   8939 C CD  . PRO D 1 264 ? 106.156 122.074 134.027 1.00 31.09  ? 338 PRO D CD  1 
ATOM   8940 N N   . ASN D 1 265 ? 103.033 123.072 131.993 1.00 24.56  ? 339 ASN D N   1 
ATOM   8941 C CA  . ASN D 1 265 ? 101.723 123.633 131.684 1.00 23.43  ? 339 ASN D CA  1 
ATOM   8942 C C   . ASN D 1 265 ? 101.646 124.228 130.282 1.00 29.85  ? 339 ASN D C   1 
ATOM   8943 O O   . ASN D 1 265 ? 100.756 125.041 130.012 1.00 36.70  ? 339 ASN D O   1 
ATOM   8944 C CB  . ASN D 1 265 ? 101.326 124.685 132.722 1.00 31.66  ? 339 ASN D CB  1 
ATOM   8945 C CG  . ASN D 1 265 ? 100.860 124.071 134.027 1.00 33.95  ? 339 ASN D CG  1 
ATOM   8946 O OD1 . ASN D 1 265 ? 100.160 123.060 134.032 1.00 34.43  ? 339 ASN D OD1 1 
ATOM   8947 N ND2 . ASN D 1 265 ? 101.224 124.694 135.140 1.00 39.92  ? 339 ASN D ND2 1 
ATOM   8948 N N   . VAL D 1 266 ? 102.555 123.851 129.388 1.00 28.60  ? 340 VAL D N   1 
ATOM   8949 C CA  . VAL D 1 266 ? 102.446 124.257 127.989 1.00 30.03  ? 340 VAL D CA  1 
ATOM   8950 C C   . VAL D 1 266 ? 102.259 123.010 127.131 1.00 32.86  ? 340 VAL D C   1 
ATOM   8951 O O   . VAL D 1 266 ? 102.883 121.972 127.398 1.00 34.82  ? 340 VAL D O   1 
ATOM   8952 C CB  . VAL D 1 266 ? 103.668 125.072 127.534 1.00 25.50  ? 340 VAL D CB  1 
ATOM   8953 C CG1 . VAL D 1 266 ? 103.823 126.310 128.386 1.00 28.41  ? 340 VAL D CG1 1 
ATOM   8954 C CG2 . VAL D 1 266 ? 104.923 124.241 127.586 1.00 23.57  ? 340 VAL D CG2 1 
ATOM   8955 N N   . PRO D 1 267 ? 101.393 123.048 126.123 1.00 23.03  ? 341 PRO D N   1 
ATOM   8956 C CA  . PRO D 1 267 ? 101.271 121.918 125.193 1.00 30.49  ? 341 PRO D CA  1 
ATOM   8957 C C   . PRO D 1 267 ? 102.376 121.960 124.148 1.00 29.53  ? 341 PRO D C   1 
ATOM   8958 O O   . PRO D 1 267 ? 102.370 122.804 123.247 1.00 35.31  ? 341 PRO D O   1 
ATOM   8959 C CB  . PRO D 1 267 ? 99.883  122.132 124.573 1.00 33.63  ? 341 PRO D CB  1 
ATOM   8960 C CG  . PRO D 1 267 ? 99.687  123.609 124.633 1.00 30.47  ? 341 PRO D CG  1 
ATOM   8961 C CD  . PRO D 1 267 ? 100.331 124.049 125.919 1.00 20.78  ? 341 PRO D CD  1 
ATOM   8962 N N   . ALA D 1 268 ? 103.330 121.041 124.266 1.00 25.53  ? 342 ALA D N   1 
ATOM   8963 C CA  . ALA D 1 268 ? 104.475 121.043 123.368 1.00 19.31  ? 342 ALA D CA  1 
ATOM   8964 C C   . ALA D 1 268 ? 105.130 119.671 123.370 1.00 26.64  ? 342 ALA D C   1 
ATOM   8965 O O   . ALA D 1 268 ? 104.938 118.870 124.288 1.00 36.64  ? 342 ALA D O   1 
ATOM   8966 C CB  . ALA D 1 268 ? 105.489 122.119 123.764 1.00 28.59  ? 342 ALA D CB  1 
ATOM   8967 N N   . ILE D 1 269 ? 105.905 119.413 122.319 1.00 30.01  ? 343 ILE D N   1 
ATOM   8968 C CA  . ILE D 1 269 ? 106.742 118.225 122.211 1.00 21.85  ? 343 ILE D CA  1 
ATOM   8969 C C   . ILE D 1 269 ? 108.152 118.677 121.860 1.00 29.94  ? 343 ILE D C   1 
ATOM   8970 O O   . ILE D 1 269 ? 108.339 119.480 120.940 1.00 34.65  ? 343 ILE D O   1 
ATOM   8971 C CB  . ILE D 1 269 ? 106.214 117.236 121.153 1.00 19.60  ? 343 ILE D CB  1 
ATOM   8972 C CG1 . ILE D 1 269 ? 104.805 116.763 121.507 1.00 28.73  ? 343 ILE D CG1 1 
ATOM   8973 C CG2 . ILE D 1 269 ? 107.149 116.047 121.020 1.00 30.35  ? 343 ILE D CG2 1 
ATOM   8974 C CD1 . ILE D 1 269 ? 104.197 115.847 120.469 1.00 28.10  ? 343 ILE D CD1 1 
ATOM   8975 N N   . MET D 1 270 ? 109.137 118.172 122.593 1.00 30.20  ? 344 MET D N   1 
ATOM   8976 C CA  . MET D 1 270 ? 110.529 118.506 122.339 1.00 23.34  ? 344 MET D CA  1 
ATOM   8977 C C   . MET D 1 270 ? 111.162 117.497 121.393 1.00 31.68  ? 344 MET D C   1 
ATOM   8978 O O   . MET D 1 270 ? 110.777 116.326 121.354 1.00 40.69  ? 344 MET D O   1 
ATOM   8979 C CB  . MET D 1 270 ? 111.328 118.542 123.641 1.00 34.54  ? 344 MET D CB  1 
ATOM   8980 C CG  . MET D 1 270 ? 110.874 119.574 124.648 1.00 40.26  ? 344 MET D CG  1 
ATOM   8981 S SD  . MET D 1 270 ? 112.273 120.162 125.621 1.00 57.67  ? 344 MET D SD  1 
ATOM   8982 C CE  . MET D 1 270 ? 113.107 121.193 124.417 1.00 38.87  ? 344 MET D CE  1 
ATOM   8983 N N   . ILE D 1 271 ? 112.131 117.970 120.615 1.00 28.38  ? 345 ILE D N   1 
ATOM   8984 C CA  . ILE D 1 271 ? 113.046 117.108 119.876 1.00 21.77  ? 345 ILE D CA  1 
ATOM   8985 C C   . ILE D 1 271 ? 114.458 117.596 120.163 1.00 28.70  ? 345 ILE D C   1 
ATOM   8986 O O   . ILE D 1 271 ? 114.816 118.722 119.795 1.00 31.89  ? 345 ILE D O   1 
ATOM   8987 C CB  . ILE D 1 271 ? 112.762 117.105 118.365 1.00 21.90  ? 345 ILE D CB  1 
ATOM   8988 C CG1 . ILE D 1 271 ? 111.347 116.593 118.091 1.00 27.04  ? 345 ILE D CG1 1 
ATOM   8989 C CG2 . ILE D 1 271 ? 113.784 116.251 117.635 1.00 30.53  ? 345 ILE D CG2 1 
ATOM   8990 C CD1 . ILE D 1 271 ? 110.721 117.160 116.842 1.00 34.96  ? 345 ILE D CD1 1 
ATOM   8991 N N   . THR D 1 272 ? 115.255 116.756 120.822 1.00 36.04  ? 346 THR D N   1 
ATOM   8992 C CA  . THR D 1 272 ? 116.591 117.122 121.260 1.00 32.04  ? 346 THR D CA  1 
ATOM   8993 C C   . THR D 1 272 ? 117.567 116.028 120.845 1.00 29.07  ? 346 THR D C   1 
ATOM   8994 O O   . THR D 1 272 ? 117.307 114.838 121.097 1.00 35.00  ? 346 THR D O   1 
ATOM   8995 C CB  . THR D 1 272 ? 116.631 117.330 122.782 1.00 29.88  ? 346 THR D CB  1 
ATOM   8996 O OG1 . THR D 1 272 ? 115.716 118.370 123.148 1.00 36.08  ? 346 THR D OG1 1 
ATOM   8997 C CG2 . THR D 1 272 ? 118.029 117.714 123.239 1.00 32.47  ? 346 THR D CG2 1 
ATOM   8998 N N   . PRO D 1 273 ? 118.683 116.374 120.219 1.00 28.16  ? 347 PRO D N   1 
ATOM   8999 C CA  . PRO D 1 273 ? 119.660 115.368 119.796 1.00 32.77  ? 347 PRO D CA  1 
ATOM   9000 C C   . PRO D 1 273 ? 120.450 114.827 120.982 1.00 35.35  ? 347 PRO D C   1 
ATOM   9001 O O   . PRO D 1 273 ? 120.228 115.191 122.133 1.00 40.25  ? 347 PRO D O   1 
ATOM   9002 C CB  . PRO D 1 273 ? 120.569 116.151 118.854 1.00 28.77  ? 347 PRO D CB  1 
ATOM   9003 C CG  . PRO D 1 273 ? 120.511 117.541 119.388 1.00 35.31  ? 347 PRO D CG  1 
ATOM   9004 C CD  . PRO D 1 273 ? 119.079 117.727 119.796 1.00 33.75  ? 347 PRO D CD  1 
ATOM   9005 N N   . ILE D 1 274 ? 121.385 113.934 120.671 1.00 30.03  ? 348 ILE D N   1 
ATOM   9006 C CA  . ILE D 1 274 ? 122.373 113.446 121.625 1.00 28.47  ? 348 ILE D CA  1 
ATOM   9007 C C   . ILE D 1 274 ? 123.722 113.609 120.940 1.00 38.54  ? 348 ILE D C   1 
ATOM   9008 O O   . ILE D 1 274 ? 124.144 112.735 120.175 1.00 45.62  ? 348 ILE D O   1 
ATOM   9009 C CB  . ILE D 1 274 ? 122.140 111.988 122.032 1.00 34.44  ? 348 ILE D CB  1 
ATOM   9010 C CG1 . ILE D 1 274 ? 120.721 111.792 122.553 1.00 35.23  ? 348 ILE D CG1 1 
ATOM   9011 C CG2 . ILE D 1 274 ? 123.127 111.588 123.113 1.00 40.12  ? 348 ILE D CG2 1 
ATOM   9012 C CD1 . ILE D 1 274 ? 120.310 110.343 122.674 1.00 38.72  ? 348 ILE D CD1 1 
ATOM   9013 N N   . CYS D 1 275 ? 124.397 114.725 121.203 1.00 37.69  ? 349 CYS D N   1 
ATOM   9014 C CA  . CYS D 1 275 ? 125.699 115.024 120.617 1.00 36.64  ? 349 CYS D CA  1 
ATOM   9015 C C   . CYS D 1 275 ? 125.670 114.881 119.099 1.00 37.93  ? 349 CYS D C   1 
ATOM   9016 O O   . CYS D 1 275 ? 126.343 113.999 118.550 1.00 44.28  ? 349 CYS D O   1 
ATOM   9017 C CB  . CYS D 1 275 ? 126.773 114.110 121.210 1.00 38.89  ? 349 CYS D CB  1 
ATOM   9018 S SG  . CYS D 1 275 ? 126.732 113.977 123.010 1.00 52.90  ? 349 CYS D SG  1 
ATOM   9019 N N   . PRO D 1 276 ? 124.904 115.706 118.388 1.00 32.45  ? 350 PRO D N   1 
ATOM   9020 C CA  . PRO D 1 276 ? 124.871 115.595 116.928 1.00 31.48  ? 350 PRO D CA  1 
ATOM   9021 C C   . PRO D 1 276 ? 126.198 116.005 116.313 1.00 36.60  ? 350 PRO D C   1 
ATOM   9022 O O   . PRO D 1 276 ? 126.917 116.858 116.838 1.00 42.84  ? 350 PRO D O   1 
ATOM   9023 C CB  . PRO D 1 276 ? 123.754 116.563 116.530 1.00 33.97  ? 350 PRO D CB  1 
ATOM   9024 C CG  . PRO D 1 276 ? 123.807 117.601 117.592 1.00 35.76  ? 350 PRO D CG  1 
ATOM   9025 C CD  . PRO D 1 276 ? 124.089 116.838 118.860 1.00 37.15  ? 350 PRO D CD  1 
ATOM   9026 N N   . HIS D 1 277 ? 126.520 115.388 115.180 1.00 39.52  ? 351 HIS D N   1 
ATOM   9027 C CA  . HIS D 1 277 ? 127.728 115.755 114.442 1.00 35.66  ? 351 HIS D CA  1 
ATOM   9028 C C   . HIS D 1 277 ? 127.446 116.916 113.494 1.00 38.14  ? 351 HIS D C   1 
ATOM   9029 O O   . HIS D 1 277 ? 127.723 116.875 112.297 1.00 40.74  ? 351 HIS D O   1 
ATOM   9030 C CB  . HIS D 1 277 ? 128.279 114.545 113.697 1.00 41.37  ? 351 HIS D CB  1 
ATOM   9031 C CG  . HIS D 1 277 ? 129.616 114.782 113.065 1.00 50.13  ? 351 HIS D CG  1 
ATOM   9032 N ND1 . HIS D 1 277 ? 130.775 114.897 113.801 1.00 45.64  ? 351 HIS D ND1 1 
ATOM   9033 C CD2 . HIS D 1 277 ? 129.979 114.922 111.768 1.00 47.57  ? 351 HIS D CD2 1 
ATOM   9034 C CE1 . HIS D 1 277 ? 131.794 115.101 112.986 1.00 43.99  ? 351 HIS D CE1 1 
ATOM   9035 N NE2 . HIS D 1 277 ? 131.338 115.120 111.746 1.00 46.86  ? 351 HIS D NE2 1 
ATOM   9036 N N   . SER D 1 278 ? 126.864 117.973 114.055 1.00 40.06  ? 352 SER D N   1 
ATOM   9037 C CA  . SER D 1 278 ? 126.532 119.177 113.307 1.00 34.14  ? 352 SER D CA  1 
ATOM   9038 C C   . SER D 1 278 ? 126.476 120.333 114.290 1.00 38.36  ? 352 SER D C   1 
ATOM   9039 O O   . SER D 1 278 ? 125.837 120.222 115.341 1.00 45.51  ? 352 SER D O   1 
ATOM   9040 C CB  . SER D 1 278 ? 125.195 119.028 112.573 1.00 34.62  ? 352 SER D CB  1 
ATOM   9041 O OG  . SER D 1 278 ? 124.726 120.281 112.109 1.00 38.94  ? 352 SER D OG  1 
ATOM   9042 N N   . LEU D 1 279 ? 127.146 121.433 113.952 1.00 32.85  ? 353 LEU D N   1 
ATOM   9043 C CA  . LEU D 1 279 ? 127.212 122.567 114.863 1.00 35.97  ? 353 LEU D CA  1 
ATOM   9044 C C   . LEU D 1 279 ? 125.895 123.323 114.967 1.00 39.55  ? 353 LEU D C   1 
ATOM   9045 O O   . LEU D 1 279 ? 125.737 124.122 115.895 1.00 40.71  ? 353 LEU D O   1 
ATOM   9046 C CB  . LEU D 1 279 ? 128.320 123.525 114.421 1.00 38.42  ? 353 LEU D CB  1 
ATOM   9047 C CG  . LEU D 1 279 ? 129.747 122.974 114.439 1.00 33.86  ? 353 LEU D CG  1 
ATOM   9048 C CD1 . LEU D 1 279 ? 130.722 123.998 113.882 1.00 36.44  ? 353 LEU D CD1 1 
ATOM   9049 C CD2 . LEU D 1 279 ? 130.151 122.554 115.841 1.00 35.23  ? 353 LEU D CD2 1 
ATOM   9050 N N   . SER D 1 280 ? 124.946 123.082 114.065 1.00 41.91  ? 354 SER D N   1 
ATOM   9051 C CA  . SER D 1 280 ? 123.736 123.891 113.952 1.00 37.12  ? 354 SER D CA  1 
ATOM   9052 C C   . SER D 1 280 ? 122.488 123.019 113.980 1.00 39.94  ? 354 SER D C   1 
ATOM   9053 O O   . SER D 1 280 ? 121.586 123.157 113.152 1.00 48.25  ? 354 SER D O   1 
ATOM   9054 C CB  . SER D 1 280 ? 123.763 124.730 112.679 1.00 39.30  ? 354 SER D CB  1 
ATOM   9055 O OG  . SER D 1 280 ? 123.725 123.908 111.526 1.00 47.67  ? 354 SER D OG  1 
ATOM   9056 N N   . PHE D 1 281 ? 122.414 122.102 114.940 1.00 35.34  ? 355 PHE D N   1 
ATOM   9057 C CA  . PHE D 1 281 ? 121.209 121.303 115.154 1.00 33.13  ? 355 PHE D CA  1 
ATOM   9058 C C   . PHE D 1 281 ? 120.791 121.500 116.607 1.00 32.91  ? 355 PHE D C   1 
ATOM   9059 O O   . PHE D 1 281 ? 121.168 120.724 117.488 1.00 39.37  ? 355 PHE D O   1 
ATOM   9060 C CB  . PHE D 1 281 ? 121.439 119.831 114.824 1.00 31.96  ? 355 PHE D CB  1 
ATOM   9061 C CG  . PHE D 1 281 ? 120.212 118.976 114.986 1.00 37.55  ? 355 PHE D CG  1 
ATOM   9062 C CD1 . PHE D 1 281 ? 119.200 119.014 114.046 1.00 43.41  ? 355 PHE D CD1 1 
ATOM   9063 C CD2 . PHE D 1 281 ? 120.073 118.130 116.065 1.00 39.03  ? 355 PHE D CD2 1 
ATOM   9064 C CE1 . PHE D 1 281 ? 118.075 118.228 114.181 1.00 41.24  ? 355 PHE D CE1 1 
ATOM   9065 C CE2 . PHE D 1 281 ? 118.943 117.344 116.205 1.00 37.57  ? 355 PHE D CE2 1 
ATOM   9066 C CZ  . PHE D 1 281 ? 117.946 117.395 115.264 1.00 36.96  ? 355 PHE D CZ  1 
ATOM   9067 N N   . ARG D 1 282 ? 120.015 122.552 116.852 1.00 31.43  ? 356 ARG D N   1 
ATOM   9068 C CA  . ARG D 1 282 ? 119.505 122.868 118.175 1.00 27.81  ? 356 ARG D CA  1 
ATOM   9069 C C   . ARG D 1 282 ? 118.181 122.157 118.430 1.00 36.83  ? 356 ARG D C   1 
ATOM   9070 O O   . ARG D 1 282 ? 117.450 121.836 117.487 1.00 46.95  ? 356 ARG D O   1 
ATOM   9071 C CB  . ARG D 1 282 ? 119.317 124.374 118.327 1.00 25.17  ? 356 ARG D CB  1 
ATOM   9072 C CG  . ARG D 1 282 ? 120.545 125.079 118.864 1.00 37.49  ? 356 ARG D CG  1 
ATOM   9073 C CD  . ARG D 1 282 ? 120.233 126.494 119.299 1.00 34.50  ? 356 ARG D CD  1 
ATOM   9074 N NE  . ARG D 1 282 ? 121.399 127.358 119.176 1.00 31.73  ? 356 ARG D NE  1 
ATOM   9075 C CZ  . ARG D 1 282 ? 121.346 128.681 119.126 1.00 36.53  ? 356 ARG D CZ  1 
ATOM   9076 N NH1 . ARG D 1 282 ? 120.195 129.329 119.182 1.00 41.07  ? 356 ARG D NH1 1 
ATOM   9077 N NH2 . ARG D 1 282 ? 122.478 129.371 119.017 1.00 39.92  ? 356 ARG D NH2 1 
ATOM   9078 N N   . PRO D 1 283 ? 117.857 121.893 119.696 1.00 29.77  ? 357 PRO D N   1 
ATOM   9079 C CA  . PRO D 1 283 ? 116.566 121.271 120.008 1.00 33.36  ? 357 PRO D CA  1 
ATOM   9080 C C   . PRO D 1 283 ? 115.411 122.154 119.561 1.00 31.00  ? 357 PRO D C   1 
ATOM   9081 O O   . PRO D 1 283 ? 115.486 123.383 119.616 1.00 31.90  ? 357 PRO D O   1 
ATOM   9082 C CB  . PRO D 1 283 ? 116.605 121.115 121.533 1.00 38.04  ? 357 PRO D CB  1 
ATOM   9083 C CG  . PRO D 1 283 ? 117.636 122.097 121.992 1.00 33.04  ? 357 PRO D CG  1 
ATOM   9084 C CD  . PRO D 1 283 ? 118.663 122.118 120.908 1.00 30.17  ? 357 PRO D CD  1 
ATOM   9085 N N   . ILE D 1 284 ? 114.335 121.512 119.113 1.00 31.02  ? 358 ILE D N   1 
ATOM   9086 C CA  . ILE D 1 284 ? 113.177 122.223 118.594 1.00 25.14  ? 358 ILE D CA  1 
ATOM   9087 C C   . ILE D 1 284 ? 111.956 121.865 119.429 1.00 33.76  ? 358 ILE D C   1 
ATOM   9088 O O   . ILE D 1 284 ? 111.888 120.811 120.068 1.00 41.09  ? 358 ILE D O   1 
ATOM   9089 C CB  . ILE D 1 284 ? 112.922 121.924 117.102 1.00 24.96  ? 358 ILE D CB  1 
ATOM   9090 C CG1 . ILE D 1 284 ? 112.619 120.441 116.894 1.00 30.99  ? 358 ILE D CG1 1 
ATOM   9091 C CG2 . ILE D 1 284 ? 114.118 122.340 116.265 1.00 30.33  ? 358 ILE D CG2 1 
ATOM   9092 C CD1 . ILE D 1 284 ? 112.509 120.042 115.440 1.00 36.63  ? 358 ILE D CD1 1 
ATOM   9093 N N   . VAL D 1 285 ? 110.986 122.774 119.426 1.00 31.69  ? 359 VAL D N   1 
ATOM   9094 C CA  . VAL D 1 285 ? 109.729 122.612 120.145 1.00 25.08  ? 359 VAL D CA  1 
ATOM   9095 C C   . VAL D 1 285 ? 108.598 122.681 119.131 1.00 26.99  ? 359 VAL D C   1 
ATOM   9096 O O   . VAL D 1 285 ? 108.505 123.647 118.364 1.00 37.64  ? 359 VAL D O   1 
ATOM   9097 C CB  . VAL D 1 285 ? 109.559 123.684 121.237 1.00 21.62  ? 359 VAL D CB  1 
ATOM   9098 C CG1 . VAL D 1 285 ? 108.351 123.380 122.093 1.00 31.20  ? 359 VAL D CG1 1 
ATOM   9099 C CG2 . VAL D 1 285 ? 110.811 123.772 122.095 1.00 30.24  ? 359 VAL D CG2 1 
ATOM   9100 N N   . VAL D 1 286 ? 107.742 121.668 119.128 1.00 25.62  ? 360 VAL D N   1 
ATOM   9101 C CA  . VAL D 1 286 ? 106.688 121.543 118.125 1.00 25.58  ? 360 VAL D CA  1 
ATOM   9102 C C   . VAL D 1 286 ? 105.356 121.461 118.855 1.00 27.47  ? 360 VAL D C   1 
ATOM   9103 O O   . VAL D 1 286 ? 105.302 121.101 120.044 1.00 36.16  ? 360 VAL D O   1 
ATOM   9104 C CB  . VAL D 1 286 ? 106.914 120.320 117.205 1.00 19.64  ? 360 VAL D CB  1 
ATOM   9105 C CG1 . VAL D 1 286 ? 108.219 120.463 116.442 1.00 22.29  ? 360 VAL D CG1 1 
ATOM   9106 C CG2 . VAL D 1 286 ? 106.903 119.036 118.011 1.00 29.67  ? 360 VAL D CG2 1 
ATOM   9107 N N   . PRO D 1 287 ? 104.256 121.808 118.183 1.00 25.31  ? 361 PRO D N   1 
ATOM   9108 C CA  . PRO D 1 287 ? 102.941 121.717 118.827 1.00 27.05  ? 361 PRO D CA  1 
ATOM   9109 C C   . PRO D 1 287 ? 102.608 120.289 119.229 1.00 27.45  ? 361 PRO D C   1 
ATOM   9110 O O   . PRO D 1 287 ? 103.059 119.323 118.611 1.00 35.53  ? 361 PRO D O   1 
ATOM   9111 C CB  . PRO D 1 287 ? 101.982 122.232 117.748 1.00 25.88  ? 361 PRO D CB  1 
ATOM   9112 C CG  . PRO D 1 287 ? 102.824 123.096 116.884 1.00 20.51  ? 361 PRO D CG  1 
ATOM   9113 C CD  . PRO D 1 287 ? 104.171 122.445 116.857 1.00 23.37  ? 361 PRO D CD  1 
ATOM   9114 N N   . ALA D 1 288 ? 101.811 120.164 120.291 1.00 24.09  ? 362 ALA D N   1 
ATOM   9115 C CA  . ALA D 1 288 ? 101.478 118.850 120.827 1.00 23.04  ? 362 ALA D CA  1 
ATOM   9116 C C   . ALA D 1 288 ? 100.539 118.063 119.923 1.00 26.63  ? 362 ALA D C   1 
ATOM   9117 O O   . ALA D 1 288 ? 100.422 116.844 120.087 1.00 35.60  ? 362 ALA D O   1 
ATOM   9118 C CB  . ALA D 1 288 ? 100.857 118.994 122.216 1.00 28.99  ? 362 ALA D CB  1 
ATOM   9119 N N   . GLY D 1 289 ? 99.876  118.717 118.976 1.00 32.02  ? 363 GLY D N   1 
ATOM   9120 C CA  . GLY D 1 289 ? 98.877  118.049 118.165 1.00 27.36  ? 363 GLY D CA  1 
ATOM   9121 C C   . GLY D 1 289 ? 99.384  117.490 116.852 1.00 30.20  ? 363 GLY D C   1 
ATOM   9122 O O   . GLY D 1 289 ? 98.590  117.229 115.943 1.00 35.55  ? 363 GLY D O   1 
ATOM   9123 N N   . VAL D 1 290 ? 100.693 117.298 116.731 1.00 32.55  ? 364 VAL D N   1 
ATOM   9124 C CA  . VAL D 1 290 ? 101.293 116.878 115.476 1.00 33.63  ? 364 VAL D CA  1 
ATOM   9125 C C   . VAL D 1 290 ? 101.617 115.391 115.531 1.00 26.58  ? 364 VAL D C   1 
ATOM   9126 O O   . VAL D 1 290 ? 101.664 114.768 116.595 1.00 37.37  ? 364 VAL D O   1 
ATOM   9127 C CB  . VAL D 1 290 ? 102.557 117.699 115.136 1.00 31.45  ? 364 VAL D CB  1 
ATOM   9128 C CG1 . VAL D 1 290 ? 102.220 119.178 115.022 1.00 34.86  ? 364 VAL D CG1 1 
ATOM   9129 C CG2 . VAL D 1 290 ? 103.637 117.463 116.170 1.00 26.02  ? 364 VAL D CG2 1 
ATOM   9130 N N   . GLU D 1 291 ? 101.844 114.817 114.353 1.00 34.60  ? 365 GLU D N   1 
ATOM   9131 C CA  . GLU D 1 291 ? 102.259 113.431 114.192 1.00 25.92  ? 365 GLU D CA  1 
ATOM   9132 C C   . GLU D 1 291 ? 103.773 113.378 114.042 1.00 28.97  ? 365 GLU D C   1 
ATOM   9133 O O   . GLU D 1 291 ? 104.338 114.075 113.193 1.00 39.78  ? 365 GLU D O   1 
ATOM   9134 C CB  . GLU D 1 291 ? 101.598 112.812 112.958 1.00 34.43  ? 365 GLU D CB  1 
ATOM   9135 C CG  . GLU D 1 291 ? 101.931 111.346 112.712 1.00 38.33  ? 365 GLU D CG  1 
ATOM   9136 C CD  . GLU D 1 291 ? 101.404 110.429 113.791 1.00 40.47  ? 365 GLU D CD  1 
ATOM   9137 O OE1 . GLU D 1 291 ? 100.406 110.798 114.440 1.00 40.60  ? 365 GLU D OE1 1 
ATOM   9138 O OE2 . GLU D 1 291 ? 101.986 109.342 113.992 1.00 40.81  ? 365 GLU D OE2 1 
ATOM   9139 N N   . LEU D 1 292 ? 104.429 112.558 114.859 1.00 21.68  ? 366 LEU D N   1 
ATOM   9140 C CA  . LEU D 1 292 ? 105.856 112.316 114.705 1.00 16.32  ? 366 LEU D CA  1 
ATOM   9141 C C   . LEU D 1 292 ? 106.094 110.879 114.266 1.00 20.33  ? 366 LEU D C   1 
ATOM   9142 O O   . LEU D 1 292 ? 105.449 109.954 114.762 1.00 31.58  ? 366 LEU D O   1 
ATOM   9143 C CB  . LEU D 1 292 ? 106.621 112.602 115.999 1.00 23.45  ? 366 LEU D CB  1 
ATOM   9144 C CG  . LEU D 1 292 ? 107.316 113.964 116.053 1.00 15.90  ? 366 LEU D CG  1 
ATOM   9145 C CD1 . LEU D 1 292 ? 106.303 115.089 116.060 1.00 28.42  ? 366 LEU D CD1 1 
ATOM   9146 C CD2 . LEU D 1 292 ? 108.223 114.054 117.262 1.00 26.10  ? 366 LEU D CD2 1 
ATOM   9147 N N   . LYS D 1 293 ? 107.017 110.700 113.328 1.00 22.38  ? 367 LYS D N   1 
ATOM   9148 C CA  . LYS D 1 293 ? 107.411 109.381 112.864 1.00 15.19  ? 367 LYS D CA  1 
ATOM   9149 C C   . LYS D 1 293 ? 108.929 109.316 112.828 1.00 23.20  ? 367 LYS D C   1 
ATOM   9150 O O   . LYS D 1 293 ? 109.600 110.311 112.558 1.00 39.49  ? 367 LYS D O   1 
ATOM   9151 C CB  . LYS D 1 293 ? 106.821 109.078 111.481 1.00 25.65  ? 367 LYS D CB  1 
ATOM   9152 C CG  . LYS D 1 293 ? 106.641 107.601 111.184 1.00 27.73  ? 367 LYS D CG  1 
ATOM   9153 C CD  . LYS D 1 293 ? 106.641 107.338 109.690 1.00 33.09  ? 367 LYS D CD  1 
ATOM   9154 C CE  . LYS D 1 293 ? 106.643 105.850 109.396 1.00 33.17  ? 367 LYS D CE  1 
ATOM   9155 N NZ  . LYS D 1 293 ? 105.353 105.211 109.776 1.00 35.97  ? 367 LYS D NZ  1 
ATOM   9156 N N   . ILE D 1 294 ? 109.467 108.139 113.120 1.00 20.04  ? 368 ILE D N   1 
ATOM   9157 C CA  . ILE D 1 294 ? 110.909 107.947 113.206 1.00 24.05  ? 368 ILE D CA  1 
ATOM   9158 C C   . ILE D 1 294 ? 111.255 106.611 112.567 1.00 28.69  ? 368 ILE D C   1 
ATOM   9159 O O   . ILE D 1 294 ? 110.671 105.578 112.918 1.00 34.71  ? 368 ILE D O   1 
ATOM   9160 C CB  . ILE D 1 294 ? 111.405 108.014 114.663 1.00 25.60  ? 368 ILE D CB  1 
ATOM   9161 C CG1 . ILE D 1 294 ? 111.547 109.475 115.098 1.00 22.47  ? 368 ILE D CG1 1 
ATOM   9162 C CG2 . ILE D 1 294 ? 112.715 107.268 114.826 1.00 31.10  ? 368 ILE D CG2 1 
ATOM   9163 C CD1 . ILE D 1 294 ? 111.958 109.655 116.535 1.00 27.47  ? 368 ILE D CD1 1 
ATOM   9164 N N   . MET D 1 295 ? 112.188 106.637 111.614 1.00 31.67  ? 369 MET D N   1 
ATOM   9165 C CA  . MET D 1 295 ? 112.616 105.436 110.914 1.00 29.79  ? 369 MET D CA  1 
ATOM   9166 C C   . MET D 1 295 ? 114.125 105.467 110.730 1.00 35.46  ? 369 MET D C   1 
ATOM   9167 O O   . MET D 1 295 ? 114.793 106.465 111.011 1.00 44.71  ? 369 MET D O   1 
ATOM   9168 C CB  . MET D 1 295 ? 111.939 105.290 109.543 1.00 29.77  ? 369 MET D CB  1 
ATOM   9169 C CG  . MET D 1 295 ? 110.457 105.610 109.505 1.00 38.14  ? 369 MET D CG  1 
ATOM   9170 S SD  . MET D 1 295 ? 109.817 105.594 107.821 1.00 50.16  ? 369 MET D SD  1 
ATOM   9171 C CE  . MET D 1 295 ? 109.758 103.834 107.500 1.00 41.39  ? 369 MET D CE  1 
ATOM   9172 N N   . LEU D 1 296 ? 114.658 104.349 110.245 1.00 40.16  ? 370 LEU D N   1 
ATOM   9173 C CA  . LEU D 1 296 ? 116.048 104.267 109.826 1.00 41.13  ? 370 LEU D CA  1 
ATOM   9174 C C   . LEU D 1 296 ? 116.145 104.666 108.360 1.00 46.69  ? 370 LEU D C   1 
ATOM   9175 O O   . LEU D 1 296 ? 115.354 104.203 107.533 1.00 53.69  ? 370 LEU D O   1 
ATOM   9176 C CB  . LEU D 1 296 ? 116.594 102.854 110.029 1.00 41.77  ? 370 LEU D CB  1 
ATOM   9177 C CG  . LEU D 1 296 ? 117.116 102.490 111.419 1.00 40.13  ? 370 LEU D CG  1 
ATOM   9178 C CD1 . LEU D 1 296 ? 117.841 101.156 111.378 1.00 43.02  ? 370 LEU D CD1 1 
ATOM   9179 C CD2 . LEU D 1 296 ? 118.029 103.582 111.951 1.00 45.69  ? 370 LEU D CD2 1 
ATOM   9180 N N   . SER D 1 297 ? 117.107 105.529 108.045 1.00 42.91  ? 371 SER D N   1 
ATOM   9181 C CA  . SER D 1 297 ? 117.282 105.963 106.670 1.00 43.98  ? 371 SER D CA  1 
ATOM   9182 C C   . SER D 1 297 ? 117.696 104.777 105.799 1.00 46.46  ? 371 SER D C   1 
ATOM   9183 O O   . SER D 1 297 ? 118.368 103.856 106.273 1.00 54.39  ? 371 SER D O   1 
ATOM   9184 C CB  . SER D 1 297 ? 118.328 107.073 106.589 1.00 49.78  ? 371 SER D CB  1 
ATOM   9185 O OG  . SER D 1 297 ? 119.610 106.600 106.955 1.00 51.17  ? 371 SER D OG  1 
ATOM   9186 N N   . PRO D 1 298 ? 117.287 104.759 104.528 1.00 39.79  ? 372 PRO D N   1 
ATOM   9187 C CA  . PRO D 1 298 ? 117.642 103.618 103.669 1.00 48.50  ? 372 PRO D CA  1 
ATOM   9188 C C   . PRO D 1 298 ? 119.139 103.427 103.505 1.00 52.80  ? 372 PRO D C   1 
ATOM   9189 O O   . PRO D 1 298 ? 119.599 102.284 103.390 1.00 52.25  ? 372 PRO D O   1 
ATOM   9190 C CB  . PRO D 1 298 ? 116.958 103.958 102.338 1.00 53.23  ? 372 PRO D CB  1 
ATOM   9191 C CG  . PRO D 1 298 ? 116.836 105.442 102.345 1.00 52.03  ? 372 PRO D CG  1 
ATOM   9192 C CD  . PRO D 1 298 ? 116.602 105.826 103.778 1.00 47.64  ? 372 PRO D CD  1 
ATOM   9193 N N   . GLU D 1 299 ? 119.912 104.506 103.489 1.00 59.26  ? 373 GLU D N   1 
ATOM   9194 C CA  . GLU D 1 299 ? 121.370 104.421 103.409 1.00 59.19  ? 373 GLU D CA  1 
ATOM   9195 C C   . GLU D 1 299 ? 121.992 104.585 104.795 1.00 60.56  ? 373 GLU D C   1 
ATOM   9196 O O   . GLU D 1 299 ? 122.715 105.541 105.076 1.00 63.35  ? 373 GLU D O   1 
ATOM   9197 C CB  . GLU D 1 299 ? 121.920 105.480 102.451 1.00 62.16  ? 373 GLU D CB  1 
ATOM   9198 C CG  . GLU D 1 299 ? 121.545 105.255 100.995 1.00 64.09  ? 373 GLU D CG  1 
ATOM   9199 C CD  . GLU D 1 299 ? 122.047 106.362 100.088 1.00 66.64  ? 373 GLU D CD  1 
ATOM   9200 O OE1 . GLU D 1 299 ? 122.519 107.393 100.611 1.00 65.79  ? 373 GLU D OE1 1 
ATOM   9201 O OE2 . GLU D 1 299 ? 121.968 106.202 98.851  1.00 65.61  ? 373 GLU D OE2 1 
ATOM   9202 N N   . ALA D 1 300 ? 121.697 103.628 105.672 1.00 56.02  ? 374 ALA D N   1 
ATOM   9203 C CA  . ALA D 1 300 ? 122.172 103.661 107.047 1.00 57.67  ? 374 ALA D CA  1 
ATOM   9204 C C   . ALA D 1 300 ? 122.819 102.335 107.412 1.00 60.18  ? 374 ALA D C   1 
ATOM   9205 O O   . ALA D 1 300 ? 122.317 101.266 107.052 1.00 60.80  ? 374 ALA D O   1 
ATOM   9206 C CB  . ALA D 1 300 ? 121.036 103.960 108.030 1.00 57.81  ? 374 ALA D CB  1 
ATOM   9207 N N   . ARG D 1 301 ? 123.935 102.414 108.128 1.00 69.42  ? 375 ARG D N   1 
ATOM   9208 C CA  . ARG D 1 301 ? 124.603 101.247 108.679 1.00 68.03  ? 375 ARG D CA  1 
ATOM   9209 C C   . ARG D 1 301 ? 124.185 101.055 110.130 1.00 69.48  ? 375 ARG D C   1 
ATOM   9210 O O   . ARG D 1 301 ? 123.901 102.021 110.844 1.00 71.90  ? 375 ARG D O   1 
ATOM   9211 C CB  . ARG D 1 301 ? 126.123 101.388 108.584 1.00 68.96  ? 375 ARG D CB  1 
ATOM   9212 C CG  . ARG D 1 301 ? 126.658 101.360 107.163 1.00 69.61  ? 375 ARG D CG  1 
ATOM   9213 C CD  . ARG D 1 301 ? 128.170 101.498 107.139 1.00 70.34  ? 375 ARG D CD  1 
ATOM   9214 N NE  . ARG D 1 301 ? 128.694 101.493 105.778 1.00 73.01  ? 375 ARG D NE  1 
ATOM   9215 C CZ  . ARG D 1 301 ? 129.973 101.651 105.468 1.00 72.17  ? 375 ARG D CZ  1 
ATOM   9216 N NH1 . ARG D 1 301 ? 130.894 101.829 106.400 1.00 70.10  ? 375 ARG D NH1 1 
ATOM   9217 N NH2 . ARG D 1 301 ? 130.338 101.630 104.189 1.00 69.98  ? 375 ARG D NH2 1 
ATOM   9218 N N   . ASN D 1 302 ? 124.129 99.788  110.549 1.00 60.02  ? 376 ASN D N   1 
ATOM   9219 C CA  . ASN D 1 302 ? 123.725 99.390  111.896 1.00 57.65  ? 376 ASN D CA  1 
ATOM   9220 C C   . ASN D 1 302 ? 122.255 99.701  112.159 1.00 54.98  ? 376 ASN D C   1 
ATOM   9221 O O   . ASN D 1 302 ? 121.651 100.535 111.477 1.00 59.44  ? 376 ASN D O   1 
ATOM   9222 C CB  . ASN D 1 302 ? 124.605 100.063 112.955 1.00 58.61  ? 376 ASN D CB  1 
ATOM   9223 C CG  . ASN D 1 302 ? 126.057 99.641  112.864 1.00 64.62  ? 376 ASN D CG  1 
ATOM   9224 O OD1 . ASN D 1 302 ? 126.933 100.451 112.561 1.00 64.69  ? 376 ASN D OD1 1 
ATOM   9225 N ND2 . ASN D 1 302 ? 126.322 98.366  113.128 1.00 64.94  ? 376 ASN D ND2 1 
ATOM   9226 N N   . THR D 1 303 ? 121.671 99.028  113.146 1.00 47.79  ? 377 THR D N   1 
ATOM   9227 C CA  . THR D 1 303 ? 120.288 99.240  113.535 1.00 45.18  ? 377 THR D CA  1 
ATOM   9228 C C   . THR D 1 303 ? 120.224 100.268 114.662 1.00 46.23  ? 377 THR D C   1 
ATOM   9229 O O   . THR D 1 303 ? 121.245 100.772 115.136 1.00 50.39  ? 377 THR D O   1 
ATOM   9230 C CB  . THR D 1 303 ? 119.642 97.920  113.957 1.00 46.00  ? 377 THR D CB  1 
ATOM   9231 O OG1 . THR D 1 303 ? 120.519 97.223  114.849 1.00 47.42  ? 377 THR D OG1 1 
ATOM   9232 C CG2 . THR D 1 303 ? 119.377 97.049  112.740 1.00 46.85  ? 377 THR D CG2 1 
ATOM   9233 N N   . ALA D 1 304 ? 119.008 100.586 115.096 1.00 45.20  ? 378 ALA D N   1 
ATOM   9234 C CA  . ALA D 1 304 ? 118.812 101.555 116.163 1.00 40.20  ? 378 ALA D CA  1 
ATOM   9235 C C   . ALA D 1 304 ? 118.155 100.882 117.359 1.00 47.37  ? 378 ALA D C   1 
ATOM   9236 O O   . ALA D 1 304 ? 117.608 99.782  117.255 1.00 50.72  ? 378 ALA D O   1 
ATOM   9237 C CB  . ALA D 1 304 ? 117.967 102.745 115.692 1.00 45.02  ? 378 ALA D CB  1 
ATOM   9238 N N   . TRP D 1 305 ? 118.209 101.556 118.505 1.00 44.82  ? 379 TRP D N   1 
ATOM   9239 C CA  . TRP D 1 305 ? 117.695 101.015 119.754 1.00 43.95  ? 379 TRP D CA  1 
ATOM   9240 C C   . TRP D 1 305 ? 116.788 102.047 120.404 1.00 41.07  ? 379 TRP D C   1 
ATOM   9241 O O   . TRP D 1 305 ? 117.197 103.192 120.612 1.00 46.89  ? 379 TRP D O   1 
ATOM   9242 C CB  . TRP D 1 305 ? 118.849 100.641 120.687 1.00 44.43  ? 379 TRP D CB  1 
ATOM   9243 C CG  . TRP D 1 305 ? 119.589 99.414  120.254 1.00 44.50  ? 379 TRP D CG  1 
ATOM   9244 C CD1 . TRP D 1 305 ? 120.713 99.366  119.485 1.00 49.44  ? 379 TRP D CD1 1 
ATOM   9245 C CD2 . TRP D 1 305 ? 119.274 98.058  120.589 1.00 46.23  ? 379 TRP D CD2 1 
ATOM   9246 N NE1 . TRP D 1 305 ? 121.108 98.064  119.304 1.00 50.74  ? 379 TRP D NE1 1 
ATOM   9247 C CE2 . TRP D 1 305 ? 120.243 97.241  119.975 1.00 46.21  ? 379 TRP D CE2 1 
ATOM   9248 C CE3 . TRP D 1 305 ? 118.266 97.455  121.344 1.00 46.60  ? 379 TRP D CE3 1 
ATOM   9249 C CZ2 . TRP D 1 305 ? 120.231 95.854  120.092 1.00 45.03  ? 379 TRP D CZ2 1 
ATOM   9250 C CZ3 . TRP D 1 305 ? 118.255 96.079  121.459 1.00 44.66  ? 379 TRP D CZ3 1 
ATOM   9251 C CH2 . TRP D 1 305 ? 119.230 95.293  120.836 1.00 44.61  ? 379 TRP D CH2 1 
ATOM   9252 N N   . VAL D 1 306 ? 115.566 101.641 120.733 1.00 32.24  ? 380 VAL D N   1 
ATOM   9253 C CA  . VAL D 1 306 ? 114.551 102.535 121.278 1.00 25.61  ? 380 VAL D CA  1 
ATOM   9254 C C   . VAL D 1 306 ? 114.256 102.135 122.719 1.00 34.49  ? 380 VAL D C   1 
ATOM   9255 O O   . VAL D 1 306 ? 114.069 100.949 123.023 1.00 44.04  ? 380 VAL D O   1 
ATOM   9256 C CB  . VAL D 1 306 ? 113.278 102.537 120.411 1.00 33.82  ? 380 VAL D CB  1 
ATOM   9257 C CG1 . VAL D 1 306 ? 112.689 101.146 120.293 1.00 39.98  ? 380 VAL D CG1 1 
ATOM   9258 C CG2 . VAL D 1 306 ? 112.256 103.499 120.979 1.00 32.19  ? 380 VAL D CG2 1 
ATOM   9259 N N   . SER D 1 307 ? 114.239 103.130 123.605 1.00 36.69  ? 381 SER D N   1 
ATOM   9260 C CA  . SER D 1 307 ? 113.984 102.947 125.025 1.00 35.66  ? 381 SER D CA  1 
ATOM   9261 C C   . SER D 1 307 ? 112.878 103.892 125.471 1.00 32.64  ? 381 SER D C   1 
ATOM   9262 O O   . SER D 1 307 ? 112.765 105.019 124.980 1.00 32.25  ? 381 SER D O   1 
ATOM   9263 C CB  . SER D 1 307 ? 115.242 103.203 125.863 1.00 36.51  ? 381 SER D CB  1 
ATOM   9264 O OG  . SER D 1 307 ? 115.641 104.560 125.783 1.00 43.77  ? 381 SER D OG  1 
ATOM   9265 N N   . PHE D 1 308 ? 112.069 103.421 126.417 1.00 36.31  ? 382 PHE D N   1 
ATOM   9266 C CA  . PHE D 1 308 ? 110.910 104.153 126.918 1.00 30.51  ? 382 PHE D CA  1 
ATOM   9267 C C   . PHE D 1 308 ? 111.114 104.424 128.403 1.00 37.03  ? 382 PHE D C   1 
ATOM   9268 O O   . PHE D 1 308 ? 110.985 103.512 129.227 1.00 48.87  ? 382 PHE D O   1 
ATOM   9269 C CB  . PHE D 1 308 ? 109.625 103.366 126.671 1.00 37.65  ? 382 PHE D CB  1 
ATOM   9270 C CG  . PHE D 1 308 ? 109.484 102.867 125.261 1.00 36.85  ? 382 PHE D CG  1 
ATOM   9271 C CD1 . PHE D 1 308 ? 108.865 103.642 124.298 1.00 35.40  ? 382 PHE D CD1 1 
ATOM   9272 C CD2 . PHE D 1 308 ? 109.971 101.623 124.899 1.00 38.12  ? 382 PHE D CD2 1 
ATOM   9273 C CE1 . PHE D 1 308 ? 108.737 103.188 123.002 1.00 35.20  ? 382 PHE D CE1 1 
ATOM   9274 C CE2 . PHE D 1 308 ? 109.845 101.166 123.604 1.00 37.28  ? 382 PHE D CE2 1 
ATOM   9275 C CZ  . PHE D 1 308 ? 109.228 101.950 122.655 1.00 36.67  ? 382 PHE D CZ  1 
ATOM   9276 N N   . ASP D 1 309 ? 111.433 105.677 128.738 1.00 38.88  ? 383 ASP D N   1 
ATOM   9277 C CA  . ASP D 1 309 ? 111.695 106.097 130.116 1.00 34.84  ? 383 ASP D CA  1 
ATOM   9278 C C   . ASP D 1 309 ? 112.817 105.284 130.756 1.00 37.72  ? 383 ASP D C   1 
ATOM   9279 O O   . ASP D 1 309 ? 112.818 105.053 131.967 1.00 46.12  ? 383 ASP D O   1 
ATOM   9280 C CB  . ASP D 1 309 ? 110.430 106.025 130.977 1.00 38.05  ? 383 ASP D CB  1 
ATOM   9281 C CG  . ASP D 1 309 ? 109.409 107.078 130.602 1.00 44.16  ? 383 ASP D CG  1 
ATOM   9282 O OD1 . ASP D 1 309 ? 109.808 108.239 130.374 1.00 49.17  ? 383 ASP D OD1 1 
ATOM   9283 O OD2 . ASP D 1 309 ? 108.207 106.748 130.539 1.00 46.62  ? 383 ASP D OD2 1 
ATOM   9284 N N   . GLY D 1 310 ? 113.784 104.848 129.952 1.00 41.30  ? 384 GLY D N   1 
ATOM   9285 C CA  . GLY D 1 310 ? 114.895 104.065 130.445 1.00 40.40  ? 384 GLY D CA  1 
ATOM   9286 C C   . GLY D 1 310 ? 114.658 102.572 130.513 1.00 40.63  ? 384 GLY D C   1 
ATOM   9287 O O   . GLY D 1 310 ? 115.585 101.832 130.865 1.00 50.00  ? 384 GLY D O   1 
ATOM   9288 N N   . ARG D 1 311 ? 113.458 102.105 130.190 1.00 40.98  ? 385 ARG D N   1 
ATOM   9289 C CA  . ARG D 1 311 ? 113.126 100.687 130.200 1.00 39.92  ? 385 ARG D CA  1 
ATOM   9290 C C   . ARG D 1 311 ? 112.580 100.281 128.835 1.00 45.38  ? 385 ARG D C   1 
ATOM   9291 O O   . ARG D 1 311 ? 112.403 101.110 127.939 1.00 46.81  ? 385 ARG D O   1 
ATOM   9292 C CB  . ARG D 1 311 ? 112.115 100.364 131.305 1.00 45.50  ? 385 ARG D CB  1 
ATOM   9293 C CG  . ARG D 1 311 ? 112.722 100.222 132.692 1.00 49.63  ? 385 ARG D CG  1 
ATOM   9294 C CD  . ARG D 1 311 ? 112.830 101.568 133.387 1.00 50.54  ? 385 ARG D CD  1 
ATOM   9295 N NE  . ARG D 1 311 ? 111.514 102.125 133.677 1.00 51.37  ? 385 ARG D NE  1 
ATOM   9296 C CZ  . ARG D 1 311 ? 111.296 103.374 134.062 1.00 53.81  ? 385 ARG D CZ  1 
ATOM   9297 N NH1 . ARG D 1 311 ? 112.289 104.235 134.214 1.00 52.85  ? 385 ARG D NH1 1 
ATOM   9298 N NH2 . ARG D 1 311 ? 110.049 103.771 134.299 1.00 49.97  ? 385 ARG D NH2 1 
ATOM   9299 N N   . LYS D 1 312 ? 112.301 98.985  128.694 1.00 48.60  ? 386 LYS D N   1 
ATOM   9300 C CA  . LYS D 1 312 ? 111.789 98.401  127.455 1.00 49.81  ? 386 LYS D CA  1 
ATOM   9301 C C   . LYS D 1 312 ? 112.683 98.774  126.271 1.00 53.07  ? 386 LYS D C   1 
ATOM   9302 O O   . LYS D 1 312 ? 112.242 99.320  125.258 1.00 55.11  ? 386 LYS D O   1 
ATOM   9303 C CB  . LYS D 1 312 ? 110.333 98.813  127.217 1.00 47.95  ? 386 LYS D CB  1 
ATOM   9304 C CG  . LYS D 1 312 ? 109.515 98.960  128.496 1.00 51.99  ? 386 LYS D CG  1 
ATOM   9305 C CD  . LYS D 1 312 ? 108.228 99.731  128.256 1.00 51.48  ? 386 LYS D CD  1 
ATOM   9306 C CE  . LYS D 1 312 ? 107.695 100.338 129.545 1.00 54.89  ? 386 LYS D CE  1 
ATOM   9307 N NZ  . LYS D 1 312 ? 107.290 99.299  130.532 1.00 54.10  ? 386 LYS D NZ  1 
ATOM   9308 N N   . ARG D 1 313 ? 113.966 98.462  126.428 1.00 48.19  ? 387 ARG D N   1 
ATOM   9309 C CA  . ARG D 1 313 ? 114.998 98.803  125.452 1.00 46.24  ? 387 ARG D CA  1 
ATOM   9310 C C   . ARG D 1 313 ? 114.999 97.735  124.366 1.00 47.21  ? 387 ARG D C   1 
ATOM   9311 O O   . ARG D 1 313 ? 115.526 96.637  124.560 1.00 54.04  ? 387 ARG D O   1 
ATOM   9312 C CB  . ARG D 1 313 ? 116.354 98.898  126.144 1.00 47.21  ? 387 ARG D CB  1 
ATOM   9313 C CG  . ARG D 1 313 ? 117.534 99.236  125.254 1.00 45.01  ? 387 ARG D CG  1 
ATOM   9314 C CD  . ARG D 1 313 ? 117.422 100.649 124.723 1.00 50.27  ? 387 ARG D CD  1 
ATOM   9315 N NE  . ARG D 1 313 ? 118.540 101.008 123.860 1.00 56.70  ? 387 ARG D NE  1 
ATOM   9316 C CZ  . ARG D 1 313 ? 119.671 101.552 124.290 1.00 55.59  ? 387 ARG D CZ  1 
ATOM   9317 N NH1 . ARG D 1 313 ? 119.878 101.788 125.575 1.00 51.19  ? 387 ARG D NH1 1 
ATOM   9318 N NH2 . ARG D 1 313 ? 120.616 101.866 123.410 1.00 57.01  ? 387 ARG D NH2 1 
ATOM   9319 N N   . GLN D 1 314 ? 114.410 98.046  123.217 1.00 40.56  ? 388 GLN D N   1 
ATOM   9320 C CA  . GLN D 1 314 ? 114.307 97.095  122.115 1.00 40.51  ? 388 GLN D CA  1 
ATOM   9321 C C   . GLN D 1 314 ? 114.987 97.667  120.873 1.00 44.84  ? 388 GLN D C   1 
ATOM   9322 O O   . GLN D 1 314 ? 115.508 98.781  120.883 1.00 47.98  ? 388 GLN D O   1 
ATOM   9323 C CB  . GLN D 1 314 ? 112.845 96.730  121.837 1.00 41.23  ? 388 GLN D CB  1 
ATOM   9324 C CG  . GLN D 1 314 ? 112.001 97.865  121.301 1.00 43.62  ? 388 GLN D CG  1 
ATOM   9325 C CD  . GLN D 1 314 ? 110.523 97.536  121.289 1.00 47.86  ? 388 GLN D CD  1 
ATOM   9326 O OE1 . GLN D 1 314 ? 109.933 97.240  122.328 1.00 47.28  ? 388 GLN D OE1 1 
ATOM   9327 N NE2 . GLN D 1 314 ? 109.914 97.587  120.110 1.00 48.69  ? 388 GLN D NE2 1 
ATOM   9328 N N   . GLU D 1 315 ? 114.983 96.887  119.795 1.00 48.47  ? 389 GLU D N   1 
ATOM   9329 C CA  . GLU D 1 315 ? 115.756 97.192  118.599 1.00 45.03  ? 389 GLU D CA  1 
ATOM   9330 C C   . GLU D 1 315 ? 114.837 97.417  117.406 1.00 46.84  ? 389 GLU D C   1 
ATOM   9331 O O   . GLU D 1 315 ? 113.878 96.667  117.198 1.00 52.38  ? 389 GLU D O   1 
ATOM   9332 C CB  . GLU D 1 315 ? 116.743 96.062  118.289 1.00 46.54  ? 389 GLU D CB  1 
ATOM   9333 C CG  . GLU D 1 315 ? 117.464 96.201  116.962 1.00 49.06  ? 389 GLU D CG  1 
ATOM   9334 C CD  . GLU D 1 315 ? 118.343 95.007  116.652 1.00 49.75  ? 389 GLU D CD  1 
ATOM   9335 O OE1 . GLU D 1 315 ? 117.991 93.884  117.069 1.00 52.80  ? 389 GLU D OE1 1 
ATOM   9336 O OE2 . GLU D 1 315 ? 119.387 95.192  115.993 1.00 51.62  ? 389 GLU D OE2 1 
ATOM   9337 N N   . ILE D 1 316 ? 115.137 98.453  116.626 1.00 46.69  ? 390 ILE D N   1 
ATOM   9338 C CA  . ILE D 1 316 ? 114.420 98.759  115.394 1.00 47.12  ? 390 ILE D CA  1 
ATOM   9339 C C   . ILE D 1 316 ? 115.397 98.674  114.228 1.00 47.68  ? 390 ILE D C   1 
ATOM   9340 O O   . ILE D 1 316 ? 116.499 99.239  114.282 1.00 50.70  ? 390 ILE D O   1 
ATOM   9341 C CB  . ILE D 1 316 ? 113.733 100.137 115.452 1.00 42.64  ? 390 ILE D CB  1 
ATOM   9342 C CG1 . ILE D 1 316 ? 114.734 101.242 115.787 1.00 42.98  ? 390 ILE D CG1 1 
ATOM   9343 C CG2 . ILE D 1 316 ? 112.599 100.123 116.465 1.00 45.19  ? 390 ILE D CG2 1 
ATOM   9344 C CD1 . ILE D 1 316 ? 114.273 102.623 115.378 1.00 47.43  ? 390 ILE D CD1 1 
ATOM   9345 N N   . ARG D 1 317 ? 114.999 97.937  113.194 1.00 50.46  ? 391 ARG D N   1 
ATOM   9346 C CA  . ARG D 1 317 ? 115.759 97.726  111.975 1.00 46.22  ? 391 ARG D CA  1 
ATOM   9347 C C   . ARG D 1 317 ? 115.184 98.591  110.853 1.00 50.56  ? 391 ARG D C   1 
ATOM   9348 O O   . ARG D 1 317 ? 114.357 99.479  111.083 1.00 56.95  ? 391 ARG D O   1 
ATOM   9349 C CB  . ARG D 1 317 ? 115.755 96.239  111.615 1.00 46.45  ? 391 ARG D CB  1 
ATOM   9350 C CG  . ARG D 1 317 ? 116.105 95.330  112.780 1.00 47.44  ? 391 ARG D CG  1 
ATOM   9351 C CD  . ARG D 1 317 ? 115.420 93.981  112.664 1.00 45.55  ? 391 ARG D CD  1 
ATOM   9352 N NE  . ARG D 1 317 ? 116.148 92.937  113.374 1.00 49.52  ? 391 ARG D NE  1 
ATOM   9353 C CZ  . ARG D 1 317 ? 116.133 92.774  114.690 1.00 55.25  ? 391 ARG D CZ  1 
ATOM   9354 N NH1 . ARG D 1 317 ? 115.426 93.568  115.477 1.00 54.09  ? 391 ARG D NH1 1 
ATOM   9355 N NH2 . ARG D 1 317 ? 116.843 91.787  115.230 1.00 55.47  ? 391 ARG D NH2 1 
ATOM   9356 N N   . HIS D 1 318 ? 115.636 98.337  109.621 1.00 52.59  ? 392 HIS D N   1 
ATOM   9357 C CA  . HIS D 1 318 ? 115.237 99.166  108.487 1.00 54.91  ? 392 HIS D CA  1 
ATOM   9358 C C   . HIS D 1 318 ? 113.734 99.123  108.239 1.00 54.85  ? 392 HIS D C   1 
ATOM   9359 O O   . HIS D 1 318 ? 113.156 100.110 107.771 1.00 57.88  ? 392 HIS D O   1 
ATOM   9360 C CB  . HIS D 1 318 ? 115.984 98.721  107.230 1.00 52.68  ? 392 HIS D CB  1 
ATOM   9361 C CG  . HIS D 1 318 ? 117.323 99.366  107.061 1.00 55.36  ? 392 HIS D CG  1 
ATOM   9362 N ND1 . HIS D 1 318 ? 118.482 98.820  107.570 1.00 60.59  ? 392 HIS D ND1 1 
ATOM   9363 C CD2 . HIS D 1 318 ? 117.689 100.513 106.440 1.00 55.62  ? 392 HIS D CD2 1 
ATOM   9364 C CE1 . HIS D 1 318 ? 119.503 99.602  107.270 1.00 59.42  ? 392 HIS D CE1 1 
ATOM   9365 N NE2 . HIS D 1 318 ? 119.049 100.636 106.585 1.00 58.00  ? 392 HIS D NE2 1 
ATOM   9366 N N   . GLY D 1 319 ? 113.087 98.003  108.540 1.00 50.49  ? 393 GLY D N   1 
ATOM   9367 C CA  . GLY D 1 319 ? 111.674 97.841  108.274 1.00 55.15  ? 393 GLY D CA  1 
ATOM   9368 C C   . GLY D 1 319 ? 110.738 98.289  109.374 1.00 58.95  ? 393 GLY D C   1 
ATOM   9369 O O   . GLY D 1 319 ? 109.525 98.084  109.253 1.00 58.21  ? 393 GLY D O   1 
ATOM   9370 N N   . ASP D 1 320 ? 111.250 98.893  110.440 1.00 54.63  ? 394 ASP D N   1 
ATOM   9371 C CA  . ASP D 1 320 ? 110.437 99.278  111.583 1.00 46.30  ? 394 ASP D CA  1 
ATOM   9372 C C   . ASP D 1 320 ? 110.173 100.779 111.577 1.00 47.02  ? 394 ASP D C   1 
ATOM   9373 O O   . ASP D 1 320 ? 110.898 101.561 110.957 1.00 54.14  ? 394 ASP D O   1 
ATOM   9374 C CB  . ASP D 1 320 ? 111.120 98.872  112.891 1.00 51.93  ? 394 ASP D CB  1 
ATOM   9375 C CG  . ASP D 1 320 ? 111.586 97.431  112.880 1.00 57.55  ? 394 ASP D CG  1 
ATOM   9376 O OD1 . ASP D 1 320 ? 110.732 96.525  112.864 1.00 57.49  ? 394 ASP D OD1 1 
ATOM   9377 O OD2 . ASP D 1 320 ? 112.810 97.201  112.868 1.00 59.25  ? 394 ASP D OD2 1 
ATOM   9378 N N   . SER D 1 321 ? 109.114 101.175 112.281 1.00 37.19  ? 395 SER D N   1 
ATOM   9379 C CA  . SER D 1 321 ? 108.740 102.577 112.390 1.00 31.72  ? 395 SER D CA  1 
ATOM   9380 C C   . SER D 1 321 ? 108.264 102.871 113.804 1.00 35.52  ? 395 SER D C   1 
ATOM   9381 O O   . SER D 1 321 ? 107.715 102.000 114.485 1.00 42.95  ? 395 SER D O   1 
ATOM   9382 C CB  . SER D 1 321 ? 107.645 102.949 111.383 1.00 35.55  ? 395 SER D CB  1 
ATOM   9383 O OG  . SER D 1 321 ? 106.433 102.276 111.676 1.00 43.39  ? 395 SER D OG  1 
ATOM   9384 N N   . ILE D 1 322 ? 108.477 104.111 114.240 1.00 29.87  ? 396 ILE D N   1 
ATOM   9385 C CA  . ILE D 1 322 ? 108.025 104.581 115.545 1.00 30.02  ? 396 ILE D CA  1 
ATOM   9386 C C   . ILE D 1 322 ? 107.117 105.783 115.330 1.00 33.51  ? 396 ILE D C   1 
ATOM   9387 O O   . ILE D 1 322 ? 107.492 106.728 114.630 1.00 39.92  ? 396 ILE D O   1 
ATOM   9388 C CB  . ILE D 1 322 ? 109.212 104.944 116.456 1.00 26.87  ? 396 ILE D CB  1 
ATOM   9389 C CG1 . ILE D 1 322 ? 110.042 103.698 116.769 1.00 25.25  ? 396 ILE D CG1 1 
ATOM   9390 C CG2 . ILE D 1 322 ? 108.727 105.599 117.735 1.00 30.84  ? 396 ILE D CG2 1 
ATOM   9391 C CD1 . ILE D 1 322 ? 111.366 103.998 117.425 1.00 35.05  ? 396 ILE D CD1 1 
ATOM   9392 N N   . SER D 1 323 ? 105.929 105.750 115.929 1.00 20.88  ? 397 SER D N   1 
ATOM   9393 C CA  . SER D 1 323 ? 104.953 106.825 115.801 1.00 19.58  ? 397 SER D CA  1 
ATOM   9394 C C   . SER D 1 323 ? 104.694 107.430 117.172 1.00 24.70  ? 397 SER D C   1 
ATOM   9395 O O   . SER D 1 323 ? 104.379 106.709 118.122 1.00 39.43  ? 397 SER D O   1 
ATOM   9396 C CB  . SER D 1 323 ? 103.647 106.314 115.188 1.00 36.58  ? 397 SER D CB  1 
ATOM   9397 O OG  . SER D 1 323 ? 103.851 105.856 113.864 1.00 43.95  ? 397 SER D OG  1 
ATOM   9398 N N   . ILE D 1 324 ? 104.819 108.751 117.268 1.00 24.42  ? 398 ILE D N   1 
ATOM   9399 C CA  . ILE D 1 324 ? 104.733 109.475 118.530 1.00 19.44  ? 398 ILE D CA  1 
ATOM   9400 C C   . ILE D 1 324 ? 103.661 110.548 118.411 1.00 18.56  ? 398 ILE D C   1 
ATOM   9401 O O   . ILE D 1 324 ? 103.660 111.332 117.451 1.00 36.37  ? 398 ILE D O   1 
ATOM   9402 C CB  . ILE D 1 324 ? 106.087 110.097 118.918 1.00 18.39  ? 398 ILE D CB  1 
ATOM   9403 C CG1 . ILE D 1 324 ? 107.147 109.008 119.087 1.00 26.02  ? 398 ILE D CG1 1 
ATOM   9404 C CG2 . ILE D 1 324 ? 105.955 110.909 120.194 1.00 25.80  ? 398 ILE D CG2 1 
ATOM   9405 C CD1 . ILE D 1 324 ? 108.560 109.506 118.929 1.00 28.11  ? 398 ILE D CD1 1 
ATOM   9406 N N   . THR D 1 325 ? 102.752 110.573 119.386 1.00 28.01  ? 399 THR D N   1 
ATOM   9407 C CA  . THR D 1 325 ? 101.714 111.587 119.500 1.00 25.76  ? 399 THR D CA  1 
ATOM   9408 C C   . THR D 1 325 ? 101.591 111.996 120.960 1.00 30.24  ? 399 THR D C   1 
ATOM   9409 O O   . THR D 1 325 ? 102.174 111.375 121.850 1.00 37.71  ? 399 THR D O   1 
ATOM   9410 C CB  . THR D 1 325 ? 100.359 111.082 118.992 1.00 27.92  ? 399 THR D CB  1 
ATOM   9411 O OG1 . THR D 1 325 ? 100.093 109.786 119.543 1.00 36.15  ? 399 THR D OG1 1 
ATOM   9412 C CG2 . THR D 1 325 ? 100.355 110.993 117.487 1.00 32.99  ? 399 THR D CG2 1 
ATOM   9413 N N   . THR D 1 326 ? 100.808 113.042 121.208 1.00 28.47  ? 400 THR D N   1 
ATOM   9414 C CA  . THR D 1 326 ? 100.495 113.454 122.569 1.00 21.68  ? 400 THR D CA  1 
ATOM   9415 C C   . THR D 1 326 ? 99.297  112.659 123.071 1.00 29.25  ? 400 THR D C   1 
ATOM   9416 O O   . THR D 1 326 ? 98.230  112.670 122.448 1.00 40.31  ? 400 THR D O   1 
ATOM   9417 C CB  . THR D 1 326 ? 100.202 114.952 122.641 1.00 29.44  ? 400 THR D CB  1 
ATOM   9418 O OG1 . THR D 1 326 ? 101.333 115.686 122.159 1.00 36.61  ? 400 THR D OG1 1 
ATOM   9419 C CG2 . THR D 1 326 ? 99.911  115.368 124.074 1.00 28.46  ? 400 THR D CG2 1 
ATOM   9420 N N   . SER D 1 327 ? 99.478  111.972 124.194 1.00 29.85  ? 401 SER D N   1 
ATOM   9421 C CA  . SER D 1 327 ? 98.442  111.101 124.721 1.00 27.98  ? 401 SER D CA  1 
ATOM   9422 C C   . SER D 1 327 ? 97.281  111.913 125.290 1.00 36.28  ? 401 SER D C   1 
ATOM   9423 O O   . SER D 1 327 ? 97.423  113.079 125.667 1.00 43.60  ? 401 SER D O   1 
ATOM   9424 C CB  . SER D 1 327 ? 99.014  110.182 125.800 1.00 32.99  ? 401 SER D CB  1 
ATOM   9425 O OG  . SER D 1 327 ? 98.018  109.316 126.314 1.00 40.04  ? 401 SER D OG  1 
ATOM   9426 N N   . THR D 1 328 ? 96.117  111.272 125.345 1.00 34.12  ? 402 THR D N   1 
ATOM   9427 C CA  . THR D 1 328 ? 94.915  111.869 125.909 1.00 33.71  ? 402 THR D CA  1 
ATOM   9428 C C   . THR D 1 328 ? 94.738  111.548 127.386 1.00 40.09  ? 402 THR D C   1 
ATOM   9429 O O   . THR D 1 328 ? 93.703  111.899 127.963 1.00 40.42  ? 402 THR D O   1 
ATOM   9430 C CB  . THR D 1 328 ? 93.678  111.403 125.134 1.00 35.38  ? 402 THR D CB  1 
ATOM   9431 O OG1 . THR D 1 328 ? 93.564  109.978 125.223 1.00 33.31  ? 402 THR D OG1 1 
ATOM   9432 C CG2 . THR D 1 328 ? 93.783  111.806 123.673 1.00 38.43  ? 402 THR D CG2 1 
ATOM   9433 N N   . TYR D 1 329 ? 95.718  110.892 128.010 1.00 38.47  ? 403 TYR D N   1 
ATOM   9434 C CA  . TYR D 1 329 ? 95.644  110.471 129.408 1.00 29.20  ? 403 TYR D CA  1 
ATOM   9435 C C   . TYR D 1 329 ? 96.818  111.080 130.163 1.00 30.57  ? 403 TYR D C   1 
ATOM   9436 O O   . TYR D 1 329 ? 97.883  110.454 130.284 1.00 34.82  ? 403 TYR D O   1 
ATOM   9437 C CB  . TYR D 1 329 ? 95.652  108.949 129.518 1.00 28.45  ? 403 TYR D CB  1 
ATOM   9438 C CG  . TYR D 1 329 ? 94.506  108.276 128.799 1.00 31.81  ? 403 TYR D CG  1 
ATOM   9439 C CD1 . TYR D 1 329 ? 93.203  108.727 128.953 1.00 35.70  ? 403 TYR D CD1 1 
ATOM   9440 C CD2 . TYR D 1 329 ? 94.729  107.194 127.959 1.00 34.26  ? 403 TYR D CD2 1 
ATOM   9441 C CE1 . TYR D 1 329 ? 92.153  108.115 128.298 1.00 34.16  ? 403 TYR D CE1 1 
ATOM   9442 C CE2 . TYR D 1 329 ? 93.687  106.576 127.299 1.00 27.81  ? 403 TYR D CE2 1 
ATOM   9443 C CZ  . TYR D 1 329 ? 92.402  107.040 127.471 1.00 29.31  ? 403 TYR D CZ  1 
ATOM   9444 O OH  . TYR D 1 329 ? 91.360  106.427 126.814 1.00 37.78  ? 403 TYR D OH  1 
ATOM   9445 N N   . PRO D 1 330 ? 96.672  112.295 130.684 1.00 32.22  ? 404 PRO D N   1 
ATOM   9446 C CA  . PRO D 1 330 ? 97.765  112.916 131.439 1.00 32.29  ? 404 PRO D CA  1 
ATOM   9447 C C   . PRO D 1 330 ? 97.948  112.254 132.796 1.00 36.77  ? 404 PRO D C   1 
ATOM   9448 O O   . PRO D 1 330 ? 97.101  111.501 133.279 1.00 43.19  ? 404 PRO D O   1 
ATOM   9449 C CB  . PRO D 1 330 ? 97.311  114.372 131.587 1.00 35.53  ? 404 PRO D CB  1 
ATOM   9450 C CG  . PRO D 1 330 ? 96.248  114.555 130.541 1.00 34.85  ? 404 PRO D CG  1 
ATOM   9451 C CD  . PRO D 1 330 ? 95.560  113.232 130.473 1.00 33.99  ? 404 PRO D CD  1 
ATOM   9452 N N   . LEU D 1 331 ? 99.087  112.557 133.418 1.00 30.72  ? 405 LEU D N   1 
ATOM   9453 C CA  . LEU D 1 331 ? 99.396  112.080 134.763 1.00 18.23  ? 405 LEU D CA  1 
ATOM   9454 C C   . LEU D 1 331 ? 99.246  113.227 135.752 1.00 32.33  ? 405 LEU D C   1 
ATOM   9455 O O   . LEU D 1 331 ? 100.126 114.098 135.831 1.00 38.70  ? 405 LEU D O   1 
ATOM   9456 C CB  . LEU D 1 331 ? 100.815 111.507 134.822 1.00 26.04  ? 405 LEU D CB  1 
ATOM   9457 C CG  . LEU D 1 331 ? 101.299 110.988 136.180 1.00 22.98  ? 405 LEU D CG  1 
ATOM   9458 C CD1 . LEU D 1 331 ? 100.482 109.800 136.647 1.00 33.63  ? 405 LEU D CD1 1 
ATOM   9459 C CD2 . LEU D 1 331 ? 102.770 110.630 136.126 1.00 27.64  ? 405 LEU D CD2 1 
ATOM   9460 N N   . PRO D 1 332 ? 98.159  113.280 136.525 1.00 30.82  ? 406 PRO D N   1 
ATOM   9461 C CA  . PRO D 1 332 ? 97.999  114.352 137.520 1.00 23.52  ? 406 PRO D CA  1 
ATOM   9462 C C   . PRO D 1 332 ? 98.862  114.081 138.744 1.00 30.06  ? 406 PRO D C   1 
ATOM   9463 O O   . PRO D 1 332 ? 98.708  113.056 139.412 1.00 42.64  ? 406 PRO D O   1 
ATOM   9464 C CB  . PRO D 1 332 ? 96.505  114.299 137.859 1.00 29.57  ? 406 PRO D CB  1 
ATOM   9465 C CG  . PRO D 1 332 ? 96.105  112.897 137.551 1.00 28.41  ? 406 PRO D CG  1 
ATOM   9466 C CD  . PRO D 1 332 ? 96.935  112.475 136.377 1.00 30.48  ? 406 PRO D CD  1 
ATOM   9467 N N   . SER D 1 333 ? 99.773  115.003 139.037 1.00 21.74  ? 407 SER D N   1 
ATOM   9468 C CA  . SER D 1 333 ? 100.626 114.919 140.215 1.00 23.75  ? 407 SER D CA  1 
ATOM   9469 C C   . SER D 1 333 ? 100.281 116.071 141.147 1.00 27.88  ? 407 SER D C   1 
ATOM   9470 O O   . SER D 1 333 ? 100.345 117.239 140.747 1.00 37.01  ? 407 SER D O   1 
ATOM   9471 C CB  . SER D 1 333 ? 102.106 114.948 139.834 1.00 28.82  ? 407 SER D CB  1 
ATOM   9472 O OG  . SER D 1 333 ? 102.471 116.197 139.282 1.00 33.43  ? 407 SER D OG  1 
ATOM   9473 N N   . ILE D 1 334 ? 99.916  115.739 142.384 1.00 23.96  ? 408 ILE D N   1 
ATOM   9474 C CA  . ILE D 1 334 ? 99.496  116.750 143.344 1.00 20.43  ? 408 ILE D CA  1 
ATOM   9475 C C   . ILE D 1 334 ? 100.698 117.579 143.771 1.00 31.54  ? 408 ILE D C   1 
ATOM   9476 O O   . ILE D 1 334 ? 101.756 117.039 144.120 1.00 42.34  ? 408 ILE D O   1 
ATOM   9477 C CB  . ILE D 1 334 ? 98.812  116.090 144.549 1.00 22.98  ? 408 ILE D CB  1 
ATOM   9478 C CG1 . ILE D 1 334 ? 97.775  115.071 144.075 1.00 20.97  ? 408 ILE D CG1 1 
ATOM   9479 C CG2 . ILE D 1 334 ? 98.172  117.140 145.437 1.00 34.46  ? 408 ILE D CG2 1 
ATOM   9480 C CD1 . ILE D 1 334 ? 97.308  114.126 145.152 1.00 28.54  ? 408 ILE D CD1 1 
ATOM   9481 N N   . CYS D 1 335 ? 100.539 118.897 143.745 1.00 29.42  ? 409 CYS D N   1 
ATOM   9482 C CA  . CYS D 1 335 ? 101.595 119.830 144.106 1.00 26.83  ? 409 CYS D CA  1 
ATOM   9483 C C   . CYS D 1 335 ? 101.384 120.336 145.526 1.00 36.06  ? 409 CYS D C   1 
ATOM   9484 O O   . CYS D 1 335 ? 100.251 120.455 146.000 1.00 42.26  ? 409 CYS D O   1 
ATOM   9485 C CB  . CYS D 1 335 ? 101.634 121.006 143.128 1.00 36.42  ? 409 CYS D CB  1 
ATOM   9486 S SG  . CYS D 1 335 ? 100.155 122.039 143.145 1.00 54.97  ? 409 CYS D SG  1 
ATOM   9487 N N   . VAL D 1 336 ? 102.492 120.630 146.209 1.00 34.08  ? 410 VAL D N   1 
ATOM   9488 C CA  . VAL D 1 336 ? 102.407 121.005 147.618 1.00 27.13  ? 410 VAL D CA  1 
ATOM   9489 C C   . VAL D 1 336 ? 101.755 122.377 147.779 1.00 30.02  ? 410 VAL D C   1 
ATOM   9490 O O   . VAL D 1 336 ? 100.839 122.546 148.593 1.00 38.91  ? 410 VAL D O   1 
ATOM   9491 C CB  . VAL D 1 336 ? 103.793 120.935 148.288 1.00 24.05  ? 410 VAL D CB  1 
ATOM   9492 C CG1 . VAL D 1 336 ? 104.274 119.497 148.337 1.00 34.32  ? 410 VAL D CG1 1 
ATOM   9493 C CG2 . VAL D 1 336 ? 104.807 121.777 147.549 1.00 30.40  ? 410 VAL D CG2 1 
ATOM   9494 N N   . ARG D 1 337 ? 102.205 123.376 147.018 1.00 28.45  ? 411 ARG D N   1 
ATOM   9495 C CA  . ARG D 1 337 ? 101.582 124.693 147.100 1.00 36.42  ? 411 ARG D CA  1 
ATOM   9496 C C   . ARG D 1 337 ? 101.002 125.182 145.780 1.00 37.62  ? 411 ARG D C   1 
ATOM   9497 O O   . ARG D 1 337 ? 99.815  125.529 145.734 1.00 44.11  ? 411 ARG D O   1 
ATOM   9498 C CB  . ARG D 1 337 ? 102.573 125.717 147.687 1.00 36.05  ? 411 ARG D CB  1 
ATOM   9499 C CG  . ARG D 1 337 ? 103.889 125.894 146.959 1.00 37.69  ? 411 ARG D CG  1 
ATOM   9500 C CD  . ARG D 1 337 ? 104.761 126.880 147.719 1.00 42.23  ? 411 ARG D CD  1 
ATOM   9501 N NE  . ARG D 1 337 ? 106.016 127.168 147.036 1.00 45.82  ? 411 ARG D NE  1 
ATOM   9502 C CZ  . ARG D 1 337 ? 107.133 126.472 147.189 1.00 47.31  ? 411 ARG D CZ  1 
ATOM   9503 N NH1 . ARG D 1 337 ? 107.190 125.425 147.995 1.00 44.48  ? 411 ARG D NH1 1 
ATOM   9504 N NH2 . ARG D 1 337 ? 108.222 126.839 146.520 1.00 45.71  ? 411 ARG D NH2 1 
ATOM   9505 N N   . ASP D 1 338 ? 101.782 125.220 144.701 1.00 37.90  ? 412 ASP D N   1 
ATOM   9506 C CA  . ASP D 1 338 ? 101.260 125.609 143.396 1.00 35.88  ? 412 ASP D CA  1 
ATOM   9507 C C   . ASP D 1 338 ? 102.238 125.147 142.325 1.00 38.37  ? 412 ASP D C   1 
ATOM   9508 O O   . ASP D 1 338 ? 103.404 124.865 142.626 1.00 43.13  ? 412 ASP D O   1 
ATOM   9509 C CB  . ASP D 1 338 ? 101.026 127.130 143.305 1.00 37.10  ? 412 ASP D CB  1 
ATOM   9510 C CG  . ASP D 1 338 ? 102.241 127.938 143.690 1.00 45.21  ? 412 ASP D CG  1 
ATOM   9511 O OD1 . ASP D 1 338 ? 102.885 127.600 144.697 1.00 48.89  ? 412 ASP D OD1 1 
ATOM   9512 O OD2 . ASP D 1 338 ? 102.550 128.918 142.980 1.00 44.82  ? 412 ASP D OD2 1 
ATOM   9513 N N   . PRO D 1 339 ? 101.792 125.052 141.065 1.00 32.89  ? 413 PRO D N   1 
ATOM   9514 C CA  . PRO D 1 339 ? 102.679 124.505 140.018 1.00 31.87  ? 413 PRO D CA  1 
ATOM   9515 C C   . PRO D 1 339 ? 103.960 125.294 139.796 1.00 36.38  ? 413 PRO D C   1 
ATOM   9516 O O   . PRO D 1 339 ? 105.052 124.711 139.832 1.00 43.56  ? 413 PRO D O   1 
ATOM   9517 C CB  . PRO D 1 339 ? 101.784 124.522 138.772 1.00 33.30  ? 413 PRO D CB  1 
ATOM   9518 C CG  . PRO D 1 339 ? 100.401 124.471 139.292 1.00 34.40  ? 413 PRO D CG  1 
ATOM   9519 C CD  . PRO D 1 339 ? 100.407 125.210 140.589 1.00 36.14  ? 413 PRO D CD  1 
ATOM   9520 N N   . VAL D 1 340 ? 103.859 126.601 139.543 1.00 34.14  ? 414 VAL D N   1 
ATOM   9521 C CA  . VAL D 1 340 ? 105.031 127.371 139.133 1.00 32.63  ? 414 VAL D CA  1 
ATOM   9522 C C   . VAL D 1 340 ? 106.068 127.430 140.251 1.00 35.15  ? 414 VAL D C   1 
ATOM   9523 O O   . VAL D 1 340 ? 107.273 127.277 140.007 1.00 42.64  ? 414 VAL D O   1 
ATOM   9524 C CB  . VAL D 1 340 ? 104.611 128.774 138.653 1.00 38.95  ? 414 VAL D CB  1 
ATOM   9525 C CG1 . VAL D 1 340 ? 103.706 128.661 137.439 1.00 37.38  ? 414 VAL D CG1 1 
ATOM   9526 C CG2 . VAL D 1 340 ? 103.898 129.544 139.754 1.00 35.83  ? 414 VAL D CG2 1 
ATOM   9527 N N   . SER D 1 341 ? 105.625 127.647 141.492 1.00 33.56  ? 415 SER D N   1 
ATOM   9528 C CA  . SER D 1 341 ? 106.565 127.731 142.604 1.00 34.49  ? 415 SER D CA  1 
ATOM   9529 C C   . SER D 1 341 ? 107.273 126.403 142.827 1.00 36.91  ? 415 SER D C   1 
ATOM   9530 O O   . SER D 1 341 ? 108.479 126.371 143.097 1.00 46.00  ? 415 SER D O   1 
ATOM   9531 C CB  . SER D 1 341 ? 105.842 128.175 143.874 1.00 39.72  ? 415 SER D CB  1 
ATOM   9532 O OG  . SER D 1 341 ? 105.322 129.485 143.733 1.00 43.69  ? 415 SER D OG  1 
ATOM   9533 N N   . ASP D 1 342 ? 106.539 125.293 142.720 1.00 28.09  ? 416 ASP D N   1 
ATOM   9534 C CA  . ASP D 1 342 ? 107.160 123.985 142.889 1.00 30.72  ? 416 ASP D CA  1 
ATOM   9535 C C   . ASP D 1 342 ? 108.141 123.689 141.763 1.00 33.83  ? 416 ASP D C   1 
ATOM   9536 O O   . ASP D 1 342 ? 109.222 123.139 142.004 1.00 37.97  ? 416 ASP D O   1 
ATOM   9537 C CB  . ASP D 1 342 ? 106.088 122.903 142.977 1.00 35.92  ? 416 ASP D CB  1 
ATOM   9538 C CG  . ASP D 1 342 ? 105.258 123.023 144.232 1.00 47.39  ? 416 ASP D CG  1 
ATOM   9539 O OD1 . ASP D 1 342 ? 105.775 123.575 145.225 1.00 48.58  ? 416 ASP D OD1 1 
ATOM   9540 O OD2 . ASP D 1 342 ? 104.099 122.565 144.233 1.00 45.44  ? 416 ASP D OD2 1 
ATOM   9541 N N   . TRP D 1 343 ? 107.791 124.061 140.530 1.00 33.94  ? 417 TRP D N   1 
ATOM   9542 C CA  . TRP D 1 343 ? 108.717 123.883 139.417 1.00 28.14  ? 417 TRP D CA  1 
ATOM   9543 C C   . TRP D 1 343 ? 110.000 124.670 139.642 1.00 33.69  ? 417 TRP D C   1 
ATOM   9544 O O   . TRP D 1 343 ? 111.105 124.152 139.430 1.00 40.29  ? 417 TRP D O   1 
ATOM   9545 C CB  . TRP D 1 343 ? 108.049 124.309 138.110 1.00 32.28  ? 417 TRP D CB  1 
ATOM   9546 C CG  . TRP D 1 343 ? 108.816 123.928 136.881 1.00 32.69  ? 417 TRP D CG  1 
ATOM   9547 C CD1 . TRP D 1 343 ? 109.071 122.667 136.434 1.00 29.81  ? 417 TRP D CD1 1 
ATOM   9548 C CD2 . TRP D 1 343 ? 109.425 124.818 135.938 1.00 37.07  ? 417 TRP D CD2 1 
ATOM   9549 N NE1 . TRP D 1 343 ? 109.802 122.714 135.273 1.00 32.77  ? 417 TRP D NE1 1 
ATOM   9550 C CE2 . TRP D 1 343 ? 110.033 124.025 134.947 1.00 30.96  ? 417 TRP D CE2 1 
ATOM   9551 C CE3 . TRP D 1 343 ? 109.516 126.210 135.837 1.00 37.57  ? 417 TRP D CE3 1 
ATOM   9552 C CZ2 . TRP D 1 343 ? 110.722 124.575 133.870 1.00 31.84  ? 417 TRP D CZ2 1 
ATOM   9553 C CZ3 . TRP D 1 343 ? 110.199 126.753 134.767 1.00 33.63  ? 417 TRP D CZ3 1 
ATOM   9554 C CH2 . TRP D 1 343 ? 110.794 125.938 133.798 1.00 32.80  ? 417 TRP D CH2 1 
ATOM   9555 N N   . PHE D 1 344 ? 109.878 125.916 140.102 1.00 33.56  ? 418 PHE D N   1 
ATOM   9556 C CA  . PHE D 1 344 ? 111.067 126.744 140.266 1.00 25.83  ? 418 PHE D CA  1 
ATOM   9557 C C   . PHE D 1 344 ? 111.906 126.299 141.460 1.00 28.19  ? 418 PHE D C   1 
ATOM   9558 O O   . PHE D 1 344 ? 113.140 126.341 141.402 1.00 37.14  ? 418 PHE D O   1 
ATOM   9559 C CB  . PHE D 1 344 ? 110.672 128.214 140.380 1.00 24.90  ? 418 PHE D CB  1 
ATOM   9560 C CG  . PHE D 1 344 ? 110.538 128.898 139.049 1.00 30.78  ? 418 PHE D CG  1 
ATOM   9561 C CD1 . PHE D 1 344 ? 111.653 129.389 138.393 1.00 34.06  ? 418 PHE D CD1 1 
ATOM   9562 C CD2 . PHE D 1 344 ? 109.301 129.028 138.444 1.00 32.91  ? 418 PHE D CD2 1 
ATOM   9563 C CE1 . PHE D 1 344 ? 111.533 130.010 137.165 1.00 35.86  ? 418 PHE D CE1 1 
ATOM   9564 C CE2 . PHE D 1 344 ? 109.175 129.647 137.216 1.00 31.11  ? 418 PHE D CE2 1 
ATOM   9565 C CZ  . PHE D 1 344 ? 110.293 130.138 136.576 1.00 32.78  ? 418 PHE D CZ  1 
ATOM   9566 N N   . GLU D 1 345 ? 111.270 125.843 142.545 1.00 26.08  ? 419 GLU D N   1 
ATOM   9567 C CA  . GLU D 1 345 ? 112.064 125.325 143.655 1.00 28.60  ? 419 GLU D CA  1 
ATOM   9568 C C   . GLU D 1 345 ? 112.746 124.016 143.280 1.00 33.23  ? 419 GLU D C   1 
ATOM   9569 O O   . GLU D 1 345 ? 113.870 123.761 143.723 1.00 38.84  ? 419 GLU D O   1 
ATOM   9570 C CB  . GLU D 1 345 ? 111.218 125.128 144.915 1.00 32.03  ? 419 GLU D CB  1 
ATOM   9571 C CG  . GLU D 1 345 ? 110.143 124.067 144.816 1.00 38.26  ? 419 GLU D CG  1 
ATOM   9572 C CD  . GLU D 1 345 ? 109.307 123.964 146.074 1.00 44.89  ? 419 GLU D CD  1 
ATOM   9573 O OE1 . GLU D 1 345 ? 109.556 124.742 147.018 1.00 45.55  ? 419 GLU D OE1 1 
ATOM   9574 O OE2 . GLU D 1 345 ? 108.404 123.102 146.121 1.00 40.50  ? 419 GLU D OE2 1 
ATOM   9575 N N   . SER D 1 346 ? 112.091 123.175 142.475 1.00 33.78  ? 420 SER D N   1 
ATOM   9576 C CA  . SER D 1 346 ? 112.750 121.970 141.989 1.00 25.01  ? 420 SER D CA  1 
ATOM   9577 C C   . SER D 1 346 ? 113.944 122.322 141.114 1.00 29.04  ? 420 SER D C   1 
ATOM   9578 O O   . SER D 1 346 ? 115.002 121.691 141.211 1.00 36.23  ? 420 SER D O   1 
ATOM   9579 C CB  . SER D 1 346 ? 111.752 121.101 141.226 1.00 28.69  ? 420 SER D CB  1 
ATOM   9580 O OG  . SER D 1 346 ? 110.563 120.916 141.973 1.00 37.09  ? 420 SER D OG  1 
ATOM   9581 N N   . LEU D 1 347 ? 113.796 123.338 140.261 1.00 34.35  ? 421 LEU D N   1 
ATOM   9582 C CA  . LEU D 1 347 ? 114.924 123.799 139.457 1.00 31.41  ? 421 LEU D CA  1 
ATOM   9583 C C   . LEU D 1 347 ? 116.060 124.304 140.339 1.00 32.79  ? 421 LEU D C   1 
ATOM   9584 O O   . LEU D 1 347 ? 117.237 124.057 140.052 1.00 43.74  ? 421 LEU D O   1 
ATOM   9585 C CB  . LEU D 1 347 ? 114.470 124.896 138.495 1.00 34.30  ? 421 LEU D CB  1 
ATOM   9586 C CG  . LEU D 1 347 ? 113.960 124.463 137.120 1.00 34.38  ? 421 LEU D CG  1 
ATOM   9587 C CD1 . LEU D 1 347 ? 113.440 125.662 136.350 1.00 32.49  ? 421 LEU D CD1 1 
ATOM   9588 C CD2 . LEU D 1 347 ? 115.055 123.757 136.342 1.00 38.83  ? 421 LEU D CD2 1 
ATOM   9589 N N   . ALA D 1 348 ? 115.725 125.016 141.417 1.00 33.32  ? 422 ALA D N   1 
ATOM   9590 C CA  . ALA D 1 348 ? 116.753 125.593 142.279 1.00 27.14  ? 422 ALA D CA  1 
ATOM   9591 C C   . ALA D 1 348 ? 117.494 124.519 143.069 1.00 29.71  ? 422 ALA D C   1 
ATOM   9592 O O   . ALA D 1 348 ? 118.727 124.545 143.161 1.00 40.01  ? 422 ALA D O   1 
ATOM   9593 C CB  . ALA D 1 348 ? 116.126 126.619 143.222 1.00 31.41  ? 422 ALA D CB  1 
ATOM   9594 N N   . GLN D 1 349 ? 116.763 123.567 143.652 1.00 29.48  ? 423 GLN D N   1 
ATOM   9595 C CA  . GLN D 1 349 ? 117.401 122.584 144.525 1.00 26.63  ? 423 GLN D CA  1 
ATOM   9596 C C   . GLN D 1 349 ? 118.036 121.439 143.743 1.00 28.57  ? 423 GLN D C   1 
ATOM   9597 O O   . GLN D 1 349 ? 119.146 121.008 144.070 1.00 38.56  ? 423 GLN D O   1 
ATOM   9598 C CB  . GLN D 1 349 ? 116.395 122.033 145.537 1.00 30.75  ? 423 GLN D CB  1 
ATOM   9599 C CG  . GLN D 1 349 ? 115.520 123.081 146.198 1.00 33.98  ? 423 GLN D CG  1 
ATOM   9600 C CD  . GLN D 1 349 ? 116.128 123.628 147.473 1.00 37.11  ? 423 GLN D CD  1 
ATOM   9601 O OE1 . GLN D 1 349 ? 116.622 122.874 148.311 1.00 40.38  ? 423 GLN D OE1 1 
ATOM   9602 N NE2 . GLN D 1 349 ? 116.097 124.946 147.626 1.00 37.55  ? 423 GLN D NE2 1 
ATOM   9603 N N   . CYS D 1 350 ? 117.356 120.930 142.716 1.00 35.47  ? 424 CYS D N   1 
ATOM   9604 C CA  . CYS D 1 350 ? 117.862 119.761 142.007 1.00 35.17  ? 424 CYS D CA  1 
ATOM   9605 C C   . CYS D 1 350 ? 118.896 120.144 140.956 1.00 34.71  ? 424 CYS D C   1 
ATOM   9606 O O   . CYS D 1 350 ? 120.012 119.614 140.950 1.00 44.10  ? 424 CYS D O   1 
ATOM   9607 C CB  . CYS D 1 350 ? 116.704 118.997 141.363 1.00 33.46  ? 424 CYS D CB  1 
ATOM   9608 S SG  . CYS D 1 350 ? 115.509 118.319 142.535 1.00 48.48  ? 424 CYS D SG  1 
ATOM   9609 N N   . LEU D 1 351 ? 118.544 121.063 140.060 1.00 32.45  ? 425 LEU D N   1 
ATOM   9610 C CA  . LEU D 1 351 ? 119.404 121.410 138.938 1.00 28.92  ? 425 LEU D CA  1 
ATOM   9611 C C   . LEU D 1 351 ? 120.304 122.608 139.211 1.00 32.57  ? 425 LEU D C   1 
ATOM   9612 O O   . LEU D 1 351 ? 121.152 122.923 138.368 1.00 43.06  ? 425 LEU D O   1 
ATOM   9613 C CB  . LEU D 1 351 ? 118.552 121.686 137.695 1.00 33.05  ? 425 LEU D CB  1 
ATOM   9614 C CG  . LEU D 1 351 ? 118.145 120.459 136.878 1.00 30.89  ? 425 LEU D CG  1 
ATOM   9615 C CD1 . LEU D 1 351 ? 117.362 120.873 135.645 1.00 33.75  ? 425 LEU D CD1 1 
ATOM   9616 C CD2 . LEU D 1 351 ? 119.367 119.642 136.492 1.00 36.30  ? 425 LEU D CD2 1 
ATOM   9617 N N   . HIS D 1 352 ? 120.149 123.269 140.360 1.00 28.99  ? 426 HIS D N   1 
ATOM   9618 C CA  . HIS D 1 352 ? 120.934 124.458 140.703 1.00 23.34  ? 426 HIS D CA  1 
ATOM   9619 C C   . HIS D 1 352 ? 120.853 125.512 139.603 1.00 31.37  ? 426 HIS D C   1 
ATOM   9620 O O   . HIS D 1 352 ? 121.855 126.112 139.209 1.00 41.69  ? 426 HIS D O   1 
ATOM   9621 C CB  . HIS D 1 352 ? 122.387 124.092 141.008 1.00 30.14  ? 426 HIS D CB  1 
ATOM   9622 C CG  . HIS D 1 352 ? 122.534 123.026 142.047 1.00 34.84  ? 426 HIS D CG  1 
ATOM   9623 N ND1 . HIS D 1 352 ? 122.437 123.286 143.397 1.00 33.43  ? 426 HIS D ND1 1 
ATOM   9624 C CD2 . HIS D 1 352 ? 122.768 121.697 141.936 1.00 35.77  ? 426 HIS D CD2 1 
ATOM   9625 C CE1 . HIS D 1 352 ? 122.606 122.165 144.073 1.00 32.54  ? 426 HIS D CE1 1 
ATOM   9626 N NE2 . HIS D 1 352 ? 122.809 121.185 143.210 1.00 35.61  ? 426 HIS D NE2 1 
ATOM   9627 N N   . TRP D 1 353 ? 119.641 125.740 139.107 1.00 29.07  ? 427 TRP D N   1 
ATOM   9628 C CA  . TRP D 1 353 ? 119.422 126.690 138.024 1.00 25.79  ? 427 TRP D CA  1 
ATOM   9629 C C   . TRP D 1 353 ? 119.615 128.115 138.531 1.00 33.79  ? 427 TRP D C   1 
ATOM   9630 O O   . TRP D 1 353 ? 118.890 128.569 139.423 1.00 45.16  ? 427 TRP D O   1 
ATOM   9631 C CB  . TRP D 1 353 ? 118.022 126.493 137.449 1.00 33.08  ? 427 TRP D CB  1 
ATOM   9632 C CG  . TRP D 1 353 ? 117.615 127.495 136.419 1.00 34.30  ? 427 TRP D CG  1 
ATOM   9633 C CD1 . TRP D 1 353 ? 117.982 127.519 135.107 1.00 33.97  ? 427 TRP D CD1 1 
ATOM   9634 C CD2 . TRP D 1 353 ? 116.727 128.602 136.608 1.00 29.01  ? 427 TRP D CD2 1 
ATOM   9635 N NE1 . TRP D 1 353 ? 117.392 128.584 134.470 1.00 28.87  ? 427 TRP D NE1 1 
ATOM   9636 C CE2 . TRP D 1 353 ? 116.615 129.263 135.371 1.00 27.82  ? 427 TRP D CE2 1 
ATOM   9637 C CE3 . TRP D 1 353 ? 116.023 129.102 137.706 1.00 33.31  ? 427 TRP D CE3 1 
ATOM   9638 C CZ2 . TRP D 1 353 ? 115.826 130.396 135.201 1.00 33.76  ? 427 TRP D CZ2 1 
ATOM   9639 C CZ3 . TRP D 1 353 ? 115.242 130.228 137.535 1.00 32.35  ? 427 TRP D CZ3 1 
ATOM   9640 C CH2 . TRP D 1 353 ? 115.150 130.863 136.293 1.00 32.40  ? 427 TRP D CH2 1 
ATOM   9641 N N   . ASN D 1 354 ? 120.599 128.813 137.975 1.00 33.88  ? 428 ASN D N   1 
ATOM   9642 C CA  . ASN D 1 354 ? 120.937 130.190 138.340 1.00 30.04  ? 428 ASN D CA  1 
ATOM   9643 C C   . ASN D 1 354 ? 121.286 130.307 139.825 1.00 40.29  ? 428 ASN D C   1 
ATOM   9644 O O   . ASN D 1 354 ? 120.599 130.966 140.608 1.00 44.93  ? 428 ASN D O   1 
ATOM   9645 C CB  . ASN D 1 354 ? 119.812 131.158 137.964 1.00 32.14  ? 428 ASN D CB  1 
ATOM   9646 C CG  . ASN D 1 354 ? 120.333 132.526 137.570 1.00 34.93  ? 428 ASN D CG  1 
ATOM   9647 O OD1 . ASN D 1 354 ? 121.539 132.724 137.426 1.00 37.36  ? 428 ASN D OD1 1 
ATOM   9648 N ND2 . ASN D 1 354 ? 119.427 133.479 137.397 1.00 37.81  ? 428 ASN D ND2 1 
ATOM   9649 N N   . VAL D 1 355 ? 122.377 129.648 140.188 1.00 40.60  ? 429 VAL D N   1 
ATOM   9650 C CA  . VAL D 1 355 ? 122.931 129.771 141.531 1.00 37.74  ? 429 VAL D CA  1 
ATOM   9651 C C   . VAL D 1 355 ? 124.023 130.832 141.511 1.00 47.20  ? 429 VAL D C   1 
ATOM   9652 O O   . VAL D 1 355 ? 124.923 130.797 140.662 1.00 51.19  ? 429 VAL D O   1 
ATOM   9653 C CB  . VAL D 1 355 ? 123.467 128.421 142.036 1.00 41.43  ? 429 VAL D CB  1 
ATOM   9654 C CG1 . VAL D 1 355 ? 122.313 127.504 142.403 1.00 41.51  ? 429 VAL D CG1 1 
ATOM   9655 C CG2 . VAL D 1 355 ? 124.345 127.762 140.982 1.00 46.22  ? 429 VAL D CG2 1 
ATOM   9656 N N   . ARG D 1 356 ? 123.932 131.785 142.436 1.00 51.21  ? 430 ARG D N   1 
ATOM   9657 C CA  . ARG D 1 356 ? 124.853 132.919 142.504 1.00 49.72  ? 430 ARG D CA  1 
ATOM   9658 C C   . ARG D 1 356 ? 124.910 133.678 141.181 1.00 53.02  ? 430 ARG D C   1 
ATOM   9659 O O   . ARG D 1 356 ? 123.893 134.170 140.692 1.00 52.79  ? 430 ARG D O   1 
ATOM   9660 C CB  . ARG D 1 356 ? 126.257 132.458 142.904 1.00 52.37  ? 430 ARG D CB  1 
ATOM   9661 C CG  . ARG D 1 356 ? 127.255 133.593 143.065 1.00 50.70  ? 430 ARG D CG  1 
ATOM   9662 C CD  . ARG D 1 356 ? 128.614 133.078 143.509 1.00 51.22  ? 430 ARG D CD  1 
ATOM   9663 N NE  . ARG D 1 356 ? 129.570 134.161 143.704 1.00 53.90  ? 430 ARG D NE  1 
ATOM   9664 C CZ  . ARG D 1 356 ? 130.366 134.636 142.756 1.00 56.77  ? 430 ARG D CZ  1 
ATOM   9665 N NH1 . ARG D 1 356 ? 130.348 134.146 141.528 1.00 54.81  ? 430 ARG D NH1 1 
ATOM   9666 N NH2 . ARG D 1 356 ? 131.202 135.629 143.048 1.00 55.37  ? 430 ARG D NH2 1 
HETATM 9667 P PA  . NAD E 2 .   ? 134.751 143.613 138.671 1.00 48.66  ? 501 NAD A PA  1 
HETATM 9668 O O1A . NAD E 2 .   ? 133.673 144.534 139.149 1.00 48.15  ? 501 NAD A O1A 1 
HETATM 9669 O O2A . NAD E 2 .   ? 136.096 143.555 139.308 1.00 43.09  ? 501 NAD A O2A 1 
HETATM 9670 O O5B . NAD E 2 .   ? 134.208 142.070 138.662 1.00 43.26  ? 501 NAD A O5B 1 
HETATM 9671 C C5B . NAD E 2 .   ? 133.010 141.734 138.003 1.00 42.02  ? 501 NAD A C5B 1 
HETATM 9672 C C4B . NAD E 2 .   ? 132.772 140.230 138.066 1.00 38.27  ? 501 NAD A C4B 1 
HETATM 9673 O O4B . NAD E 2 .   ? 133.579 139.583 137.074 1.00 37.91  ? 501 NAD A O4B 1 
HETATM 9674 C C3B . NAD E 2 .   ? 133.122 139.580 139.402 1.00 43.16  ? 501 NAD A C3B 1 
HETATM 9675 O O3B . NAD E 2 .   ? 132.200 138.542 139.632 1.00 48.68  ? 501 NAD A O3B 1 
HETATM 9676 C C2B . NAD E 2 .   ? 134.518 139.026 139.136 1.00 36.71  ? 501 NAD A C2B 1 
HETATM 9677 O O2B . NAD E 2 .   ? 134.836 137.979 140.000 1.00 44.59  ? 501 NAD A O2B 1 
HETATM 9678 C C1B . NAD E 2 .   ? 134.388 138.607 137.669 1.00 40.12  ? 501 NAD A C1B 1 
HETATM 9679 N N9A . NAD E 2 .   ? 135.638 138.519 136.960 1.00 39.46  ? 501 NAD A N9A 1 
HETATM 9680 C C8A . NAD E 2 .   ? 136.446 139.546 136.553 1.00 39.33  ? 501 NAD A C8A 1 
HETATM 9681 N N7A . NAD E 2 .   ? 137.513 139.150 135.931 1.00 32.90  ? 501 NAD A N7A 1 
HETATM 9682 C C5A . NAD E 2 .   ? 137.412 137.783 135.922 1.00 30.07  ? 501 NAD A C5A 1 
HETATM 9683 C C6A . NAD E 2 .   ? 138.235 136.765 135.410 1.00 38.30  ? 501 NAD A C6A 1 
HETATM 9684 N N6A . NAD E 2 .   ? 139.381 137.007 134.775 1.00 44.47  ? 501 NAD A N6A 1 
HETATM 9685 N N1A . NAD E 2 .   ? 137.839 135.501 135.574 1.00 32.84  ? 501 NAD A N1A 1 
HETATM 9686 C C2A . NAD E 2 .   ? 136.696 135.255 136.205 1.00 35.37  ? 501 NAD A C2A 1 
HETATM 9687 N N3A . NAD E 2 .   ? 135.845 136.118 136.728 1.00 37.72  ? 501 NAD A N3A 1 
HETATM 9688 C C4A . NAD E 2 .   ? 136.254 137.370 136.556 1.00 32.09  ? 501 NAD A C4A 1 
HETATM 9689 O O3  . NAD E 2 .   ? 134.878 143.926 137.054 1.00 35.51  ? 501 NAD A O3  1 
HETATM 9690 P PN  . NAD E 2 .   ? 135.588 145.221 136.360 1.00 37.61  ? 501 NAD A PN  1 
HETATM 9691 O O1N . NAD E 2 .   ? 136.604 145.806 137.304 1.00 43.00  ? 501 NAD A O1N 1 
HETATM 9692 O O2N . NAD E 2 .   ? 134.573 146.103 135.709 1.00 46.79  ? 501 NAD A O2N 1 
HETATM 9693 O O5D . NAD E 2 .   ? 136.456 144.416 135.231 1.00 46.80  ? 501 NAD A O5D 1 
HETATM 9694 C C5D . NAD E 2 .   ? 135.920 144.130 133.959 1.00 41.82  ? 501 NAD A C5D 1 
HETATM 9695 C C4D . NAD E 2 .   ? 135.732 142.639 133.807 1.00 37.99  ? 501 NAD A C4D 1 
HETATM 9696 O O4D . NAD E 2 .   ? 134.328 142.312 133.735 1.00 44.10  ? 501 NAD A O4D 1 
HETATM 9697 C C3D . NAD E 2 .   ? 136.380 142.023 132.565 1.00 37.20  ? 501 NAD A C3D 1 
HETATM 9698 O O3D . NAD E 2 .   ? 137.088 140.878 132.968 1.00 49.59  ? 501 NAD A O3D 1 
HETATM 9699 C C2D . NAD E 2 .   ? 135.178 141.628 131.703 1.00 32.46  ? 501 NAD A C2D 1 
HETATM 9700 O O2D . NAD E 2 .   ? 135.387 140.507 130.906 1.00 43.07  ? 501 NAD A O2D 1 
HETATM 9701 C C1D . NAD E 2 .   ? 134.143 141.334 132.788 1.00 37.67  ? 501 NAD A C1D 1 
HETATM 9702 N N1N . NAD E 2 .   ? 132.764 141.379 132.249 1.00 38.99  ? 501 NAD A N1N 1 
HETATM 9703 C C2N . NAD E 2 .   ? 131.941 140.323 132.313 1.00 42.53  ? 501 NAD A C2N 1 
HETATM 9704 C C3N . NAD E 2 .   ? 130.661 140.412 131.802 1.00 39.23  ? 501 NAD A C3N 1 
HETATM 9705 C C7N . NAD E 2 .   ? 129.690 139.261 131.842 1.00 40.76  ? 501 NAD A C7N 1 
HETATM 9706 O O7N . NAD E 2 .   ? 129.936 138.310 132.570 1.00 46.37  ? 501 NAD A O7N 1 
HETATM 9707 N N7N . NAD E 2 .   ? 128.617 139.381 131.070 1.00 35.98  ? 501 NAD A N7N 1 
HETATM 9708 C C4N . NAD E 2 .   ? 130.249 141.607 131.224 1.00 37.54  ? 501 NAD A C4N 1 
HETATM 9709 C C5N . NAD E 2 .   ? 131.121 142.681 131.172 1.00 38.04  ? 501 NAD A C5N 1 
HETATM 9710 C C6N . NAD E 2 .   ? 132.380 142.540 131.698 1.00 38.28  ? 501 NAD A C6N 1 
HETATM 9711 P PA  . NAD F 2 .   ? 134.882 107.699 110.316 1.00 39.78  ? 501 NAD B PA  1 
HETATM 9712 O O1A . NAD F 2 .   ? 133.896 106.606 110.053 1.00 44.51  ? 501 NAD B O1A 1 
HETATM 9713 O O2A . NAD F 2 .   ? 135.546 108.459 109.220 1.00 39.13  ? 501 NAD B O2A 1 
HETATM 9714 O O5B . NAD F 2 .   ? 134.228 108.833 111.300 1.00 43.60  ? 501 NAD B O5B 1 
HETATM 9715 C C5B . NAD F 2 .   ? 132.872 109.193 111.177 1.00 41.57  ? 501 NAD B C5B 1 
HETATM 9716 C C4B . NAD F 2 .   ? 132.734 110.673 110.838 1.00 36.56  ? 501 NAD B C4B 1 
HETATM 9717 O O4B . NAD F 2 .   ? 133.528 111.441 111.752 1.00 34.51  ? 501 NAD B O4B 1 
HETATM 9718 C C3B . NAD F 2 .   ? 133.191 111.058 109.433 1.00 43.09  ? 501 NAD B C3B 1 
HETATM 9719 O O3B . NAD F 2 .   ? 132.334 112.071 108.965 1.00 45.93  ? 501 NAD B O3B 1 
HETATM 9720 C C2B . NAD F 2 .   ? 134.591 111.603 109.687 1.00 37.78  ? 501 NAD B C2B 1 
HETATM 9721 O O2B . NAD F 2 .   ? 135.002 112.464 108.672 1.00 46.87  ? 501 NAD B O2B 1 
HETATM 9722 C C1B . NAD F 2 .   ? 134.384 112.291 111.039 1.00 36.05  ? 501 NAD B C1B 1 
HETATM 9723 N N9A . NAD F 2 .   ? 135.597 112.518 111.783 1.00 38.05  ? 501 NAD B N9A 1 
HETATM 9724 C C8A . NAD F 2 .   ? 136.460 111.585 112.291 1.00 36.69  ? 501 NAD B C8A 1 
HETATM 9725 N N7A . NAD F 2 .   ? 137.472 112.104 112.914 1.00 30.28  ? 501 NAD B N7A 1 
HETATM 9726 C C5A . NAD F 2 .   ? 137.275 113.457 112.818 1.00 28.35  ? 501 NAD B C5A 1 
HETATM 9727 C C6A . NAD F 2 .   ? 138.003 114.568 113.277 1.00 32.54  ? 501 NAD B C6A 1 
HETATM 9728 N N6A . NAD F 2 .   ? 139.138 114.455 113.966 1.00 40.26  ? 501 NAD B N6A 1 
HETATM 9729 N N1A . NAD F 2 .   ? 137.525 115.786 113.007 1.00 34.73  ? 501 NAD B N1A 1 
HETATM 9730 C C2A . NAD F 2 .   ? 136.392 115.901 112.321 1.00 38.96  ? 501 NAD B C2A 1 
HETATM 9731 N N3A . NAD F 2 .   ? 135.626 114.940 111.839 1.00 41.19  ? 501 NAD B N3A 1 
HETATM 9732 C C4A . NAD F 2 .   ? 136.115 113.736 112.116 1.00 34.28  ? 501 NAD B C4A 1 
HETATM 9733 O O3  . NAD F 2 .   ? 136.013 107.013 111.308 1.00 34.96  ? 501 NAD B O3  1 
HETATM 9734 P PN  . NAD F 2 .   ? 135.759 105.859 112.434 1.00 37.28  ? 501 NAD B PN  1 
HETATM 9735 O O1N . NAD F 2 .   ? 136.554 104.633 112.073 1.00 41.05  ? 501 NAD B O1N 1 
HETATM 9736 O O2N . NAD F 2 .   ? 134.307 105.733 112.762 1.00 43.61  ? 501 NAD B O2N 1 
HETATM 9737 O O5D . NAD F 2 .   ? 136.567 106.543 113.683 1.00 46.96  ? 501 NAD B O5D 1 
HETATM 9738 C C5D . NAD F 2 .   ? 135.898 106.911 114.868 1.00 39.48  ? 501 NAD B C5D 1 
HETATM 9739 C C4D . NAD F 2 .   ? 135.748 108.410 114.956 1.00 35.31  ? 501 NAD B C4D 1 
HETATM 9740 O O4D . NAD F 2 .   ? 134.351 108.767 115.009 1.00 43.82  ? 501 NAD B O4D 1 
HETATM 9741 C C3D . NAD F 2 .   ? 136.398 109.052 116.185 1.00 35.30  ? 501 NAD B C3D 1 
HETATM 9742 O O3D . NAD F 2 .   ? 137.066 110.216 115.767 1.00 49.24  ? 501 NAD B O3D 1 
HETATM 9743 C C2D . NAD F 2 .   ? 135.194 109.416 117.058 1.00 29.08  ? 501 NAD B C2D 1 
HETATM 9744 O O2D . NAD F 2 .   ? 135.391 110.524 117.874 1.00 39.92  ? 501 NAD B O2D 1 
HETATM 9745 C C1D . NAD F 2 .   ? 134.157 109.720 115.979 1.00 35.96  ? 501 NAD B C1D 1 
HETATM 9746 N N1N . NAD F 2 .   ? 132.778 109.644 116.517 1.00 37.69  ? 501 NAD B N1N 1 
HETATM 9747 C C2N . NAD F 2 .   ? 131.948 110.696 116.497 1.00 41.18  ? 501 NAD B C2N 1 
HETATM 9748 C C3N . NAD F 2 .   ? 130.670 110.577 117.004 1.00 37.16  ? 501 NAD B C3N 1 
HETATM 9749 C C7N . NAD F 2 .   ? 129.691 111.723 117.012 1.00 39.02  ? 501 NAD B C7N 1 
HETATM 9750 O O7N . NAD F 2 .   ? 129.941 112.715 116.344 1.00 43.09  ? 501 NAD B O7N 1 
HETATM 9751 N N7N . NAD F 2 .   ? 128.606 111.552 117.759 1.00 34.81  ? 501 NAD B N7N 1 
HETATM 9752 C C4N . NAD F 2 .   ? 130.266 109.357 117.533 1.00 34.58  ? 501 NAD B C4N 1 
HETATM 9753 C C5N . NAD F 2 .   ? 131.145 108.288 117.540 1.00 35.62  ? 501 NAD B C5N 1 
HETATM 9754 C C6N . NAD F 2 .   ? 132.403 108.459 117.020 1.00 38.51  ? 501 NAD B C6N 1 
HETATM 9755 P PA  . NAD G 2 .   ? 116.282 143.406 110.410 1.00 45.53  ? 501 NAD C PA  1 
HETATM 9756 O O1A . NAD G 2 .   ? 117.284 144.008 109.477 1.00 46.83  ? 501 NAD C O1A 1 
HETATM 9757 O O2A . NAD G 2 .   ? 114.848 143.236 110.050 1.00 38.78  ? 501 NAD C O2A 1 
HETATM 9758 O O5B . NAD G 2 .   ? 116.776 141.924 110.892 1.00 44.06  ? 501 NAD C O5B 1 
HETATM 9759 C C5B . NAD G 2 .   ? 118.146 141.608 110.972 1.00 41.70  ? 501 NAD C C5B 1 
HETATM 9760 C C4B . NAD G 2 .   ? 118.346 140.114 110.752 1.00 37.48  ? 501 NAD C C4B 1 
HETATM 9761 O O4B . NAD G 2 .   ? 117.545 139.401 111.702 1.00 37.53  ? 501 NAD C O4B 1 
HETATM 9762 C C3B . NAD G 2 .   ? 117.941 139.603 109.373 1.00 44.50  ? 501 NAD C C3B 1 
HETATM 9763 O O3B . NAD G 2 .   ? 118.809 138.550 109.030 1.00 50.28  ? 501 NAD C O3B 1 
HETATM 9764 C C2B . NAD G 2 .   ? 116.528 139.088 109.620 1.00 39.96  ? 501 NAD C C2B 1 
HETATM 9765 O O2B . NAD G 2 .   ? 116.148 138.136 108.676 1.00 44.96  ? 501 NAD C O2B 1 
HETATM 9766 C C1B . NAD G 2 .   ? 116.661 138.536 111.043 1.00 38.53  ? 501 NAD C C1B 1 
HETATM 9767 N N9A . NAD G 2 .   ? 115.420 138.464 111.771 1.00 37.88  ? 501 NAD C N9A 1 
HETATM 9768 C C8A . NAD G 2 .   ? 114.630 139.501 112.189 1.00 38.19  ? 501 NAD C C8A 1 
HETATM 9769 N N7A . NAD G 2 .   ? 113.567 139.118 112.825 1.00 32.53  ? 501 NAD C N7A 1 
HETATM 9770 C C5A . NAD G 2 .   ? 113.650 137.750 112.831 1.00 31.06  ? 501 NAD C C5A 1 
HETATM 9771 C C6A . NAD G 2 .   ? 112.822 136.743 113.353 1.00 36.23  ? 501 NAD C C6A 1 
HETATM 9772 N N6A . NAD G 2 .   ? 111.688 137.000 114.004 1.00 41.88  ? 501 NAD C N6A 1 
HETATM 9773 N N1A . NAD G 2 .   ? 113.200 135.474 113.183 1.00 30.38  ? 501 NAD C N1A 1 
HETATM 9774 C C2A . NAD G 2 .   ? 114.331 135.214 112.537 1.00 36.38  ? 501 NAD C C2A 1 
HETATM 9775 N N3A . NAD G 2 .   ? 115.185 136.066 112.002 1.00 37.58  ? 501 NAD C N3A 1 
HETATM 9776 C C4A . NAD G 2 .   ? 114.795 137.323 112.180 1.00 34.37  ? 501 NAD C C4A 1 
HETATM 9777 O O3  . NAD G 2 .   ? 116.445 144.266 111.813 1.00 35.47  ? 501 NAD C O3  1 
HETATM 9778 P PN  . NAD G 2 .   ? 115.408 145.369 112.422 1.00 33.81  ? 501 NAD C PN  1 
HETATM 9779 O O1N . NAD G 2 .   ? 114.428 145.790 111.361 1.00 40.76  ? 501 NAD C O1N 1 
HETATM 9780 O O2N . NAD G 2 .   ? 116.133 146.402 113.224 1.00 49.48  ? 501 NAD C O2N 1 
HETATM 9781 O O5D . NAD G 2 .   ? 114.578 144.361 113.406 1.00 44.56  ? 501 NAD C O5D 1 
HETATM 9782 C C5D . NAD G 2 .   ? 114.990 144.121 114.733 1.00 42.09  ? 501 NAD C C5D 1 
HETATM 9783 C C4D . NAD G 2 .   ? 115.202 142.641 114.943 1.00 38.27  ? 501 NAD C C4D 1 
HETATM 9784 O O4D . NAD G 2 .   ? 116.610 142.331 115.016 1.00 45.31  ? 501 NAD C O4D 1 
HETATM 9785 C C3D . NAD G 2 .   ? 114.572 142.065 116.215 1.00 37.85  ? 501 NAD C C3D 1 
HETATM 9786 O O3D . NAD G 2 .   ? 113.853 140.912 115.859 1.00 47.88  ? 501 NAD C O3D 1 
HETATM 9787 C C2D . NAD G 2 .   ? 115.787 141.689 117.068 1.00 32.39  ? 501 NAD C C2D 1 
HETATM 9788 O O2D . NAD G 2 .   ? 115.591 140.591 117.899 1.00 41.72  ? 501 NAD C O2D 1 
HETATM 9789 C C1D . NAD G 2 .   ? 116.794 141.359 115.969 1.00 38.07  ? 501 NAD C C1D 1 
HETATM 9790 N N1N . NAD G 2 .   ? 118.182 141.366 116.486 1.00 42.02  ? 501 NAD C N1N 1 
HETATM 9791 C C2N . NAD G 2 .   ? 118.938 140.259 116.492 1.00 44.48  ? 501 NAD C C2N 1 
HETATM 9792 C C3N . NAD G 2 .   ? 120.229 140.305 116.978 1.00 38.51  ? 501 NAD C C3N 1 
HETATM 9793 C C7N . NAD G 2 .   ? 121.121 139.092 117.013 1.00 40.43  ? 501 NAD C C7N 1 
HETATM 9794 O O7N . NAD G 2 .   ? 120.770 138.085 116.414 1.00 44.31  ? 501 NAD C O7N 1 
HETATM 9795 N N7N . NAD G 2 .   ? 122.249 139.222 117.702 1.00 35.84  ? 501 NAD C N7N 1 
HETATM 9796 C C4N . NAD G 2 .   ? 120.722 141.511 117.460 1.00 34.43  ? 501 NAD C C4N 1 
HETATM 9797 C C5N . NAD G 2 .   ? 119.920 142.638 117.442 1.00 38.95  ? 501 NAD C C5N 1 
HETATM 9798 C C6N . NAD G 2 .   ? 118.645 142.539 116.944 1.00 40.49  ? 501 NAD C C6N 1 
HETATM 9799 P PA  . NAD H 2 .   ? 116.060 107.662 138.870 1.00 46.99  ? 501 NAD D PA  1 
HETATM 9800 O O1A . NAD H 2 .   ? 117.269 106.948 139.385 1.00 46.70  ? 501 NAD D O1A 1 
HETATM 9801 O O2A . NAD H 2 .   ? 115.098 108.365 139.763 1.00 46.06  ? 501 NAD D O2A 1 
HETATM 9802 O O5B . NAD H 2 .   ? 116.509 108.772 137.752 1.00 41.92  ? 501 NAD D O5B 1 
HETATM 9803 C C5B . NAD H 2 .   ? 117.874 109.062 137.552 1.00 42.46  ? 501 NAD D C5B 1 
HETATM 9804 C C4B . NAD H 2 .   ? 118.173 110.526 137.853 1.00 37.38  ? 501 NAD D C4B 1 
HETATM 9805 O O4B . NAD H 2 .   ? 117.420 111.349 136.952 1.00 37.79  ? 501 NAD D O4B 1 
HETATM 9806 C C3B . NAD H 2 .   ? 117.820 110.990 139.263 1.00 44.17  ? 501 NAD D C3B 1 
HETATM 9807 O O3B . NAD H 2 .   ? 118.773 111.949 139.652 1.00 47.81  ? 501 NAD D O3B 1 
HETATM 9808 C C2B . NAD H 2 .   ? 116.452 111.631 139.062 1.00 39.68  ? 501 NAD D C2B 1 
HETATM 9809 O O2B . NAD H 2 .   ? 116.162 112.561 140.059 1.00 45.72  ? 501 NAD D O2B 1 
HETATM 9810 C C1B . NAD H 2 .   ? 116.614 112.243 137.667 1.00 41.03  ? 501 NAD D C1B 1 
HETATM 9811 N N9A . NAD H 2 .   ? 115.373 112.441 136.964 1.00 41.22  ? 501 NAD D N9A 1 
HETATM 9812 C C8A . NAD H 2 .   ? 114.488 111.484 136.545 1.00 39.29  ? 501 NAD D C8A 1 
HETATM 9813 N N7A . NAD H 2 .   ? 113.452 111.969 135.934 1.00 36.75  ? 501 NAD D N7A 1 
HETATM 9814 C C5A . NAD H 2 .   ? 113.657 113.324 135.945 1.00 31.87  ? 501 NAD D C5A 1 
HETATM 9815 C C6A . NAD H 2 .   ? 112.912 114.409 135.452 1.00 36.58  ? 501 NAD D C6A 1 
HETATM 9816 N N6A . NAD H 2 .   ? 111.749 114.259 134.818 1.00 43.84  ? 501 NAD D N6A 1 
HETATM 9817 N N1A . NAD H 2 .   ? 113.403 115.638 135.632 1.00 34.47  ? 501 NAD D N1A 1 
HETATM 9818 C C2A . NAD H 2 .   ? 114.563 115.788 136.261 1.00 39.52  ? 501 NAD D C2A 1 
HETATM 9819 N N3A . NAD H 2 .   ? 115.347 114.855 136.769 1.00 42.47  ? 501 NAD D N3A 1 
HETATM 9820 C C4A . NAD H 2 .   ? 114.845 113.639 136.581 1.00 35.59  ? 501 NAD D C4A 1 
HETATM 9821 O O3  . NAD H 2 .   ? 115.277 106.538 137.945 1.00 38.51  ? 501 NAD D O3  1 
HETATM 9822 P PN  . NAD H 2 .   ? 115.727 105.998 136.471 1.00 39.14  ? 501 NAD D PN  1 
HETATM 9823 O O1N . NAD H 2 .   ? 115.007 104.715 136.154 1.00 40.73  ? 501 NAD D O1N 1 
HETATM 9824 O O2N . NAD H 2 .   ? 117.206 106.096 136.281 1.00 46.31  ? 501 NAD D O2N 1 
HETATM 9825 O O5D . NAD H 2 .   ? 114.953 107.138 135.593 1.00 43.50  ? 501 NAD D O5D 1 
HETATM 9826 C C5D . NAD H 2 .   ? 114.991 107.159 134.185 1.00 39.52  ? 501 NAD D C5D 1 
HETATM 9827 C C4D . NAD H 2 .   ? 115.200 108.583 133.732 1.00 39.51  ? 501 NAD D C4D 1 
HETATM 9828 O O4D . NAD H 2 .   ? 116.608 108.895 133.688 1.00 45.38  ? 501 NAD D O4D 1 
HETATM 9829 C C3D . NAD H 2 .   ? 114.634 108.929 132.353 1.00 36.20  ? 501 NAD D C3D 1 
HETATM 9830 O O3D . NAD H 2 .   ? 113.802 110.052 132.499 1.00 47.31  ? 501 NAD D O3D 1 
HETATM 9831 C C2D . NAD H 2 .   ? 115.877 109.299 131.540 1.00 33.31  ? 501 NAD D C2D 1 
HETATM 9832 O O2D . NAD H 2 .   ? 115.667 110.326 130.628 1.00 44.65  ? 501 NAD D O2D 1 
HETATM 9833 C C1D . NAD H 2 .   ? 116.834 109.751 132.641 1.00 38.56  ? 501 NAD D C1D 1 
HETATM 9834 N N1N . NAD H 2 .   ? 118.241 109.673 132.185 1.00 41.47  ? 501 NAD D N1N 1 
HETATM 9835 C C2N . NAD H 2 .   ? 119.071 110.724 132.255 1.00 45.41  ? 501 NAD D C2N 1 
HETATM 9836 C C3N . NAD H 2 .   ? 120.376 110.605 131.820 1.00 39.23  ? 501 NAD D C3N 1 
HETATM 9837 C C7N . NAD H 2 .   ? 121.353 111.749 131.871 1.00 41.80  ? 501 NAD D C7N 1 
HETATM 9838 O O7N . NAD H 2 .   ? 121.145 112.664 132.655 1.00 47.64  ? 501 NAD D O7N 1 
HETATM 9839 N N7N . NAD H 2 .   ? 122.387 111.665 131.043 1.00 39.36  ? 501 NAD D N7N 1 
HETATM 9840 C C4N . NAD H 2 .   ? 120.807 109.386 131.312 1.00 36.93  ? 501 NAD D C4N 1 
HETATM 9841 C C5N . NAD H 2 .   ? 119.929 108.318 131.253 1.00 37.16  ? 501 NAD D C5N 1 
HETATM 9842 C C6N . NAD H 2 .   ? 118.644 108.489 131.701 1.00 38.98  ? 501 NAD D C6N 1 
# 
