data_9CR4
# 
_entry.id   9CR4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CR4         pdb_00009cr4 10.2210/pdb9cr4/pdb 
WWPDB D_1000286114 ?            ?                   
EMDB  EMD-45832    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-08 
2 'Structure model' 1 1 2025-02-05 
3 'Structure model' 1 2 2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.journal_volume'          
6  2 'Structure model' '_citation.page_first'              
7  2 'Structure model' '_citation.page_last'               
8  2 'Structure model' '_citation.pdbx_database_id_DOI'    
9  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
10 2 'Structure model' '_citation.title'                   
11 2 'Structure model' '_citation.year'                    
12 2 'Structure model' '_em_admin.last_update'             
13 3 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CR4 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'CryoEM Structure of the human full length NAD Kinase'                                 EMD-45831 'other EM volume'      
EMDB 'CryoEM Structure of the C-terminally truncated form of human NAD Kinase'              EMD-45832 'associated EM volume' 
EMDB 'CryoEM Structure of the C-terminally truncated form of human NAD Kinase bound to NAD' EMD-45856 'other EM volume'      
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 gerta.hoxhaj@utsouthwestern.edu Gerta  Hoxhaj  ? 'principal investigator/group leader' 0000-0001-6179-3583 
4 gilles.labesse@cbs.cnrs.fr      Gilles Labesse ? 'principal investigator/group leader' 0000-0002-6861-3300 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, Y.'      1 0000-0001-9601-4885 
'Chen, Z.'    2 0000-0002-1668-4051 
'Mary, C.'    3 0000-0003-3056-8839 
'Labesse, G.' 4 0000-0002-6861-3300 
'Hoxhaj, G.'  5 0000-0001-6179-3583 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Sci Adv' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2375-2548 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            11 
_citation.language                  ? 
_citation.page_first                eads2664 
_citation.page_last                 eads2664 
_citation.title                     'Cryo-EM structure and regulation of human NAD kinase.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/sciadv.ads2664 
_citation.pdbx_database_id_PubMed   39854463 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Praharaj, P.P.'  1  0000-0003-0425-5118 
primary 'Li, Y.'          2  0000-0001-9601-4885 
primary 'Mary, C.'        3  ?                   
primary 'Soflaee, M.H.'   4  0000-0003-4598-3955 
primary 'Ryu, K.'         5  0009-0005-8836-2720 
primary 'Kim, D.'         6  0000-0002-6060-0601 
primary 'Tran, D.H.'      7  0000-0003-3612-1464 
primary 'Dey, T.'         8  0000-0002-5504-2481 
primary 'Tom, H.J.'       9  0000-0001-9402-2371 
primary 'Rion, H.'        10 0000-0002-7827-6352 
primary 'Gelin, M.'       11 0000-0003-1320-8663 
primary 'Lemoff, A.'      12 ?                   
primary 'Zacharias, L.G.' 13 ?                   
primary 'Patricio, J.S.'  14 0000-0001-7045-4532 
primary 'Mathews, T.P.'   15 0000-0002-9355-8243 
primary 'Chen, Z.'        16 0000-0002-1668-4051 
primary 'Lionne, C.'      17 0000-0002-6348-5311 
primary 'Hoxhaj, G.'      18 0000-0001-6179-3583 
primary 'Labesse, G.'     19 0000-0002-6861-3300 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'NAD kinase' 
_entity.formula_weight             41069.910 
_entity.pdbx_number_of_molecules   4 
_entity.pdbx_ec                    2.7.1.23 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              'C-terminal residues 91-437' 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Poly(P)/ATP NAD kinase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPSPVTTFGPKATVETQDPASVRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESF
GAVKKKFTTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAV
VLRSRLKVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD
GVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGD
SISITTSTYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFELGLEHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPSPVTTFGPKATVETQDPASVRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESF
GAVKKKFTTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAV
VLRSRLKVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD
GVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGD
SISITTSTYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFELGLEHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   SER n 
1 4   PRO n 
1 5   VAL n 
1 6   THR n 
1 7   THR n 
1 8   PHE n 
1 9   GLY n 
1 10  PRO n 
1 11  LYS n 
1 12  ALA n 
1 13  THR n 
1 14  VAL n 
1 15  GLU n 
1 16  THR n 
1 17  GLN n 
1 18  ASP n 
1 19  PRO n 
1 20  ALA n 
1 21  SER n 
1 22  VAL n 
1 23  ARG n 
1 24  LEU n 
1 25  THR n 
1 26  TRP n 
1 27  ASN n 
1 28  LYS n 
1 29  SER n 
1 30  PRO n 
1 31  LYS n 
1 32  SER n 
1 33  VAL n 
1 34  LEU n 
1 35  VAL n 
1 36  ILE n 
1 37  LYS n 
1 38  LYS n 
1 39  MET n 
1 40  ARG n 
1 41  ASP n 
1 42  ALA n 
1 43  SER n 
1 44  LEU n 
1 45  LEU n 
1 46  GLN n 
1 47  PRO n 
1 48  PHE n 
1 49  LYS n 
1 50  GLU n 
1 51  LEU n 
1 52  CYS n 
1 53  THR n 
1 54  HIS n 
1 55  LEU n 
1 56  MET n 
1 57  GLU n 
1 58  GLU n 
1 59  ASN n 
1 60  MET n 
1 61  ILE n 
1 62  VAL n 
1 63  TYR n 
1 64  VAL n 
1 65  GLU n 
1 66  LYS n 
1 67  LYS n 
1 68  VAL n 
1 69  LEU n 
1 70  GLU n 
1 71  ASP n 
1 72  PRO n 
1 73  ALA n 
1 74  ILE n 
1 75  ALA n 
1 76  SER n 
1 77  ASP n 
1 78  GLU n 
1 79  SER n 
1 80  PHE n 
1 81  GLY n 
1 82  ALA n 
1 83  VAL n 
1 84  LYS n 
1 85  LYS n 
1 86  LYS n 
1 87  PHE n 
1 88  THR n 
1 89  THR n 
1 90  PHE n 
1 91  ARG n 
1 92  GLU n 
1 93  ASP n 
1 94  TYR n 
1 95  ASP n 
1 96  ASP n 
1 97  ILE n 
1 98  SER n 
1 99  ASN n 
1 100 GLN n 
1 101 ILE n 
1 102 ASP n 
1 103 PHE n 
1 104 ILE n 
1 105 ILE n 
1 106 CYS n 
1 107 LEU n 
1 108 GLY n 
1 109 GLY n 
1 110 ASP n 
1 111 GLY n 
1 112 THR n 
1 113 LEU n 
1 114 LEU n 
1 115 TYR n 
1 116 ALA n 
1 117 SER n 
1 118 SER n 
1 119 LEU n 
1 120 PHE n 
1 121 GLN n 
1 122 GLY n 
1 123 SER n 
1 124 VAL n 
1 125 PRO n 
1 126 PRO n 
1 127 VAL n 
1 128 MET n 
1 129 ALA n 
1 130 PHE n 
1 131 HIS n 
1 132 LEU n 
1 133 GLY n 
1 134 SER n 
1 135 LEU n 
1 136 GLY n 
1 137 PHE n 
1 138 LEU n 
1 139 THR n 
1 140 PRO n 
1 141 PHE n 
1 142 SER n 
1 143 PHE n 
1 144 GLU n 
1 145 ASN n 
1 146 PHE n 
1 147 GLN n 
1 148 SER n 
1 149 GLN n 
1 150 VAL n 
1 151 THR n 
1 152 GLN n 
1 153 VAL n 
1 154 ILE n 
1 155 GLU n 
1 156 GLY n 
1 157 ASN n 
1 158 ALA n 
1 159 ALA n 
1 160 VAL n 
1 161 VAL n 
1 162 LEU n 
1 163 ARG n 
1 164 SER n 
1 165 ARG n 
1 166 LEU n 
1 167 LYS n 
1 168 VAL n 
1 169 ARG n 
1 170 VAL n 
1 171 VAL n 
1 172 LYS n 
1 173 GLU n 
1 174 LEU n 
1 175 ARG n 
1 176 GLY n 
1 177 LYS n 
1 178 LYS n 
1 179 THR n 
1 180 ALA n 
1 181 VAL n 
1 182 HIS n 
1 183 ASN n 
1 184 GLY n 
1 185 LEU n 
1 186 GLY n 
1 187 GLU n 
1 188 ASN n 
1 189 GLY n 
1 190 SER n 
1 191 GLN n 
1 192 ALA n 
1 193 ALA n 
1 194 GLY n 
1 195 LEU n 
1 196 ASP n 
1 197 MET n 
1 198 ASP n 
1 199 VAL n 
1 200 GLY n 
1 201 LYS n 
1 202 GLN n 
1 203 ALA n 
1 204 MET n 
1 205 GLN n 
1 206 TYR n 
1 207 GLN n 
1 208 VAL n 
1 209 LEU n 
1 210 ASN n 
1 211 GLU n 
1 212 VAL n 
1 213 VAL n 
1 214 ILE n 
1 215 ASP n 
1 216 ARG n 
1 217 GLY n 
1 218 PRO n 
1 219 SER n 
1 220 SER n 
1 221 TYR n 
1 222 LEU n 
1 223 SER n 
1 224 ASN n 
1 225 VAL n 
1 226 ASP n 
1 227 VAL n 
1 228 TYR n 
1 229 LEU n 
1 230 ASP n 
1 231 GLY n 
1 232 HIS n 
1 233 LEU n 
1 234 ILE n 
1 235 THR n 
1 236 THR n 
1 237 VAL n 
1 238 GLN n 
1 239 GLY n 
1 240 ASP n 
1 241 GLY n 
1 242 VAL n 
1 243 ILE n 
1 244 VAL n 
1 245 SER n 
1 246 THR n 
1 247 PRO n 
1 248 THR n 
1 249 GLY n 
1 250 SER n 
1 251 THR n 
1 252 ALA n 
1 253 TYR n 
1 254 ALA n 
1 255 ALA n 
1 256 ALA n 
1 257 ALA n 
1 258 GLY n 
1 259 ALA n 
1 260 SER n 
1 261 MET n 
1 262 ILE n 
1 263 HIS n 
1 264 PRO n 
1 265 ASN n 
1 266 VAL n 
1 267 PRO n 
1 268 ALA n 
1 269 ILE n 
1 270 MET n 
1 271 ILE n 
1 272 THR n 
1 273 PRO n 
1 274 ILE n 
1 275 CYS n 
1 276 PRO n 
1 277 HIS n 
1 278 SER n 
1 279 LEU n 
1 280 SER n 
1 281 PHE n 
1 282 ARG n 
1 283 PRO n 
1 284 ILE n 
1 285 VAL n 
1 286 VAL n 
1 287 PRO n 
1 288 ALA n 
1 289 GLY n 
1 290 VAL n 
1 291 GLU n 
1 292 LEU n 
1 293 LYS n 
1 294 ILE n 
1 295 MET n 
1 296 LEU n 
1 297 SER n 
1 298 PRO n 
1 299 GLU n 
1 300 ALA n 
1 301 ARG n 
1 302 ASN n 
1 303 THR n 
1 304 ALA n 
1 305 TRP n 
1 306 VAL n 
1 307 SER n 
1 308 PHE n 
1 309 ASP n 
1 310 GLY n 
1 311 ARG n 
1 312 LYS n 
1 313 ARG n 
1 314 GLN n 
1 315 GLU n 
1 316 ILE n 
1 317 ARG n 
1 318 HIS n 
1 319 GLY n 
1 320 ASP n 
1 321 SER n 
1 322 ILE n 
1 323 SER n 
1 324 ILE n 
1 325 THR n 
1 326 THR n 
1 327 SER n 
1 328 THR n 
1 329 TYR n 
1 330 PRO n 
1 331 LEU n 
1 332 PRO n 
1 333 SER n 
1 334 ILE n 
1 335 CYS n 
1 336 VAL n 
1 337 ARG n 
1 338 ASP n 
1 339 PRO n 
1 340 VAL n 
1 341 SER n 
1 342 ASP n 
1 343 TRP n 
1 344 PHE n 
1 345 GLU n 
1 346 SER n 
1 347 LEU n 
1 348 ALA n 
1 349 GLN n 
1 350 CYS n 
1 351 LEU n 
1 352 HIS n 
1 353 TRP n 
1 354 ASN n 
1 355 VAL n 
1 356 ARG n 
1 357 LYS n 
1 358 LYS n 
1 359 GLN n 
1 360 ALA n 
1 361 HIS n 
1 362 PHE n 
1 363 GLU n 
1 364 LEU n 
1 365 GLY n 
1 366 LEU n 
1 367 GLU n 
1 368 HIS n 
1 369 HIS n 
1 370 HIS n 
1 371 HIS n 
1 372 HIS n 
1 373 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   373 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 NADK 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   75  ?   ?   ?   A . n 
A 1 2   PRO 2   76  ?   ?   ?   A . n 
A 1 3   SER 3   77  ?   ?   ?   A . n 
A 1 4   PRO 4   78  ?   ?   ?   A . n 
A 1 5   VAL 5   79  ?   ?   ?   A . n 
A 1 6   THR 6   80  ?   ?   ?   A . n 
A 1 7   THR 7   81  ?   ?   ?   A . n 
A 1 8   PHE 8   82  ?   ?   ?   A . n 
A 1 9   GLY 9   83  ?   ?   ?   A . n 
A 1 10  PRO 10  84  ?   ?   ?   A . n 
A 1 11  LYS 11  85  ?   ?   ?   A . n 
A 1 12  ALA 12  86  ?   ?   ?   A . n 
A 1 13  THR 13  87  ?   ?   ?   A . n 
A 1 14  VAL 14  88  ?   ?   ?   A . n 
A 1 15  GLU 15  89  ?   ?   ?   A . n 
A 1 16  THR 16  90  ?   ?   ?   A . n 
A 1 17  GLN 17  91  ?   ?   ?   A . n 
A 1 18  ASP 18  92  ?   ?   ?   A . n 
A 1 19  PRO 19  93  ?   ?   ?   A . n 
A 1 20  ALA 20  94  ?   ?   ?   A . n 
A 1 21  SER 21  95  95  SER SER A . n 
A 1 22  VAL 22  96  96  VAL VAL A . n 
A 1 23  ARG 23  97  97  ARG ARG A . n 
A 1 24  LEU 24  98  98  LEU LEU A . n 
A 1 25  THR 25  99  99  THR THR A . n 
A 1 26  TRP 26  100 100 TRP TRP A . n 
A 1 27  ASN 27  101 101 ASN ASN A . n 
A 1 28  LYS 28  102 102 LYS LYS A . n 
A 1 29  SER 29  103 103 SER SER A . n 
A 1 30  PRO 30  104 104 PRO PRO A . n 
A 1 31  LYS 31  105 105 LYS LYS A . n 
A 1 32  SER 32  106 106 SER SER A . n 
A 1 33  VAL 33  107 107 VAL VAL A . n 
A 1 34  LEU 34  108 108 LEU LEU A . n 
A 1 35  VAL 35  109 109 VAL VAL A . n 
A 1 36  ILE 36  110 110 ILE ILE A . n 
A 1 37  LYS 37  111 111 LYS LYS A . n 
A 1 38  LYS 38  112 112 LYS LYS A . n 
A 1 39  MET 39  113 113 MET MET A . n 
A 1 40  ARG 40  114 114 ARG ARG A . n 
A 1 41  ASP 41  115 115 ASP ASP A . n 
A 1 42  ALA 42  116 116 ALA ALA A . n 
A 1 43  SER 43  117 117 SER SER A . n 
A 1 44  LEU 44  118 118 LEU LEU A . n 
A 1 45  LEU 45  119 119 LEU LEU A . n 
A 1 46  GLN 46  120 120 GLN GLN A . n 
A 1 47  PRO 47  121 121 PRO PRO A . n 
A 1 48  PHE 48  122 122 PHE PHE A . n 
A 1 49  LYS 49  123 123 LYS LYS A . n 
A 1 50  GLU 50  124 124 GLU GLU A . n 
A 1 51  LEU 51  125 125 LEU LEU A . n 
A 1 52  CYS 52  126 126 CYS CYS A . n 
A 1 53  THR 53  127 127 THR THR A . n 
A 1 54  HIS 54  128 128 HIS HIS A . n 
A 1 55  LEU 55  129 129 LEU LEU A . n 
A 1 56  MET 56  130 130 MET MET A . n 
A 1 57  GLU 57  131 131 GLU GLU A . n 
A 1 58  GLU 58  132 132 GLU GLU A . n 
A 1 59  ASN 59  133 133 ASN ASN A . n 
A 1 60  MET 60  134 134 MET MET A . n 
A 1 61  ILE 61  135 135 ILE ILE A . n 
A 1 62  VAL 62  136 136 VAL VAL A . n 
A 1 63  TYR 63  137 137 TYR TYR A . n 
A 1 64  VAL 64  138 138 VAL VAL A . n 
A 1 65  GLU 65  139 139 GLU GLU A . n 
A 1 66  LYS 66  140 140 LYS LYS A . n 
A 1 67  LYS 67  141 141 LYS LYS A . n 
A 1 68  VAL 68  142 142 VAL VAL A . n 
A 1 69  LEU 69  143 143 LEU LEU A . n 
A 1 70  GLU 70  144 144 GLU GLU A . n 
A 1 71  ASP 71  145 145 ASP ASP A . n 
A 1 72  PRO 72  146 146 PRO PRO A . n 
A 1 73  ALA 73  147 147 ALA ALA A . n 
A 1 74  ILE 74  148 148 ILE ILE A . n 
A 1 75  ALA 75  149 149 ALA ALA A . n 
A 1 76  SER 76  150 150 SER SER A . n 
A 1 77  ASP 77  151 151 ASP ASP A . n 
A 1 78  GLU 78  152 152 GLU GLU A . n 
A 1 79  SER 79  153 153 SER SER A . n 
A 1 80  PHE 80  154 154 PHE PHE A . n 
A 1 81  GLY 81  155 155 GLY GLY A . n 
A 1 82  ALA 82  156 156 ALA ALA A . n 
A 1 83  VAL 83  157 157 VAL VAL A . n 
A 1 84  LYS 84  158 158 LYS LYS A . n 
A 1 85  LYS 85  159 159 LYS LYS A . n 
A 1 86  LYS 86  160 160 LYS LYS A . n 
A 1 87  PHE 87  161 161 PHE PHE A . n 
A 1 88  THR 88  162 162 THR THR A . n 
A 1 89  THR 89  163 ?   ?   ?   A . n 
A 1 90  PHE 90  164 ?   ?   ?   A . n 
A 1 91  ARG 91  165 ?   ?   ?   A . n 
A 1 92  GLU 92  166 ?   ?   ?   A . n 
A 1 93  ASP 93  167 ?   ?   ?   A . n 
A 1 94  TYR 94  168 ?   ?   ?   A . n 
A 1 95  ASP 95  169 ?   ?   ?   A . n 
A 1 96  ASP 96  170 ?   ?   ?   A . n 
A 1 97  ILE 97  171 ?   ?   ?   A . n 
A 1 98  SER 98  172 172 SER ALA A . n 
A 1 99  ASN 99  173 173 ASN ASN A . n 
A 1 100 GLN 100 174 174 GLN GLN A . n 
A 1 101 ILE 101 175 175 ILE ILE A . n 
A 1 102 ASP 102 176 176 ASP ASP A . n 
A 1 103 PHE 103 177 177 PHE PHE A . n 
A 1 104 ILE 104 178 178 ILE ILE A . n 
A 1 105 ILE 105 179 179 ILE ILE A . n 
A 1 106 CYS 106 180 180 CYS CYS A . n 
A 1 107 LEU 107 181 181 LEU LEU A . n 
A 1 108 GLY 108 182 182 GLY GLY A . n 
A 1 109 GLY 109 183 183 GLY GLY A . n 
A 1 110 ASP 110 184 184 ASP ASP A . n 
A 1 111 GLY 111 185 185 GLY GLY A . n 
A 1 112 THR 112 186 186 THR THR A . n 
A 1 113 LEU 113 187 187 LEU LEU A . n 
A 1 114 LEU 114 188 188 LEU LEU A . n 
A 1 115 TYR 115 189 189 TYR TYR A . n 
A 1 116 ALA 116 190 190 ALA ALA A . n 
A 1 117 SER 117 191 191 SER SER A . n 
A 1 118 SER 118 192 192 SER SER A . n 
A 1 119 LEU 119 193 193 LEU LEU A . n 
A 1 120 PHE 120 194 194 PHE PHE A . n 
A 1 121 GLN 121 195 195 GLN GLN A . n 
A 1 122 GLY 122 196 196 GLY GLY A . n 
A 1 123 SER 123 197 197 SER SER A . n 
A 1 124 VAL 124 198 198 VAL VAL A . n 
A 1 125 PRO 125 199 199 PRO PRO A . n 
A 1 126 PRO 126 200 200 PRO PRO A . n 
A 1 127 VAL 127 201 201 VAL VAL A . n 
A 1 128 MET 128 202 202 MET MET A . n 
A 1 129 ALA 129 203 203 ALA ALA A . n 
A 1 130 PHE 130 204 204 PHE PHE A . n 
A 1 131 HIS 131 205 205 HIS HIS A . n 
A 1 132 LEU 132 206 206 LEU LEU A . n 
A 1 133 GLY 133 207 207 GLY GLY A . n 
A 1 134 SER 134 208 208 SER SER A . n 
A 1 135 LEU 135 209 209 LEU LEU A . n 
A 1 136 GLY 136 210 210 GLY GLY A . n 
A 1 137 PHE 137 211 211 PHE PHE A . n 
A 1 138 LEU 138 212 212 LEU LEU A . n 
A 1 139 THR 139 213 213 THR THR A . n 
A 1 140 PRO 140 214 214 PRO PRO A . n 
A 1 141 PHE 141 215 215 PHE PHE A . n 
A 1 142 SER 142 216 216 SER SER A . n 
A 1 143 PHE 143 217 217 PHE PHE A . n 
A 1 144 GLU 144 218 218 GLU GLU A . n 
A 1 145 ASN 145 219 219 ASN ASN A . n 
A 1 146 PHE 146 220 220 PHE PHE A . n 
A 1 147 GLN 147 221 221 GLN GLN A . n 
A 1 148 SER 148 222 222 SER SER A . n 
A 1 149 GLN 149 223 223 GLN GLN A . n 
A 1 150 VAL 150 224 224 VAL VAL A . n 
A 1 151 THR 151 225 225 THR THR A . n 
A 1 152 GLN 152 226 226 GLN GLN A . n 
A 1 153 VAL 153 227 227 VAL VAL A . n 
A 1 154 ILE 154 228 228 ILE ILE A . n 
A 1 155 GLU 155 229 229 GLU GLU A . n 
A 1 156 GLY 156 230 230 GLY GLY A . n 
A 1 157 ASN 157 231 231 ASN ASN A . n 
A 1 158 ALA 158 232 232 ALA ALA A . n 
A 1 159 ALA 159 233 233 ALA ALA A . n 
A 1 160 VAL 160 234 234 VAL VAL A . n 
A 1 161 VAL 161 235 235 VAL VAL A . n 
A 1 162 LEU 162 236 236 LEU LEU A . n 
A 1 163 ARG 163 237 237 ARG ARG A . n 
A 1 164 SER 164 238 238 SER SER A . n 
A 1 165 ARG 165 239 239 ARG ARG A . n 
A 1 166 LEU 166 240 240 LEU LEU A . n 
A 1 167 LYS 167 241 241 LYS LYS A . n 
A 1 168 VAL 168 242 242 VAL VAL A . n 
A 1 169 ARG 169 243 243 ARG ARG A . n 
A 1 170 VAL 170 244 244 VAL VAL A . n 
A 1 171 VAL 171 245 245 VAL VAL A . n 
A 1 172 LYS 172 246 246 LYS LYS A . n 
A 1 173 GLU 173 247 247 GLU GLU A . n 
A 1 174 LEU 174 248 ?   ?   ?   A . n 
A 1 175 ARG 175 249 ?   ?   ?   A . n 
A 1 176 GLY 176 250 ?   ?   ?   A . n 
A 1 177 LYS 177 251 ?   ?   ?   A . n 
A 1 178 LYS 178 252 ?   ?   ?   A . n 
A 1 179 THR 179 253 ?   ?   ?   A . n 
A 1 180 ALA 180 254 ?   ?   ?   A . n 
A 1 181 VAL 181 255 ?   ?   ?   A . n 
A 1 182 HIS 182 256 ?   ?   ?   A . n 
A 1 183 ASN 183 257 ?   ?   ?   A . n 
A 1 184 GLY 184 258 ?   ?   ?   A . n 
A 1 185 LEU 185 259 ?   ?   ?   A . n 
A 1 186 GLY 186 260 ?   ?   ?   A . n 
A 1 187 GLU 187 261 ?   ?   ?   A . n 
A 1 188 ASN 188 262 ?   ?   ?   A . n 
A 1 189 GLY 189 263 ?   ?   ?   A . n 
A 1 190 SER 190 264 ?   ?   ?   A . n 
A 1 191 GLN 191 265 ?   ?   ?   A . n 
A 1 192 ALA 192 266 ?   ?   ?   A . n 
A 1 193 ALA 193 267 ?   ?   ?   A . n 
A 1 194 GLY 194 268 ?   ?   ?   A . n 
A 1 195 LEU 195 269 ?   ?   ?   A . n 
A 1 196 ASP 196 270 ?   ?   ?   A . n 
A 1 197 MET 197 271 ?   ?   ?   A . n 
A 1 198 ASP 198 272 ?   ?   ?   A . n 
A 1 199 VAL 199 273 ?   ?   ?   A . n 
A 1 200 GLY 200 274 ?   ?   ?   A . n 
A 1 201 LYS 201 275 ?   ?   ?   A . n 
A 1 202 GLN 202 276 ?   ?   ?   A . n 
A 1 203 ALA 203 277 277 ALA ALA A . n 
A 1 204 MET 204 278 278 MET MET A . n 
A 1 205 GLN 205 279 279 GLN GLN A . n 
A 1 206 TYR 206 280 280 TYR TYR A . n 
A 1 207 GLN 207 281 281 GLN GLN A . n 
A 1 208 VAL 208 282 282 VAL VAL A . n 
A 1 209 LEU 209 283 283 LEU LEU A . n 
A 1 210 ASN 210 284 284 ASN ASN A . n 
A 1 211 GLU 211 285 285 GLU GLU A . n 
A 1 212 VAL 212 286 286 VAL VAL A . n 
A 1 213 VAL 213 287 287 VAL VAL A . n 
A 1 214 ILE 214 288 288 ILE ILE A . n 
A 1 215 ASP 215 289 289 ASP ASP A . n 
A 1 216 ARG 216 290 290 ARG ARG A . n 
A 1 217 GLY 217 291 291 GLY GLY A . n 
A 1 218 PRO 218 292 292 PRO PRO A . n 
A 1 219 SER 219 293 293 SER SER A . n 
A 1 220 SER 220 294 294 SER SER A . n 
A 1 221 TYR 221 295 295 TYR TYR A . n 
A 1 222 LEU 222 296 296 LEU LEU A . n 
A 1 223 SER 223 297 297 SER SER A . n 
A 1 224 ASN 224 298 298 ASN ASN A . n 
A 1 225 VAL 225 299 299 VAL VAL A . n 
A 1 226 ASP 226 300 300 ASP ASP A . n 
A 1 227 VAL 227 301 301 VAL VAL A . n 
A 1 228 TYR 228 302 302 TYR TYR A . n 
A 1 229 LEU 229 303 303 LEU LEU A . n 
A 1 230 ASP 230 304 304 ASP ASP A . n 
A 1 231 GLY 231 305 305 GLY GLY A . n 
A 1 232 HIS 232 306 306 HIS HIS A . n 
A 1 233 LEU 233 307 307 LEU LEU A . n 
A 1 234 ILE 234 308 308 ILE ILE A . n 
A 1 235 THR 235 309 309 THR THR A . n 
A 1 236 THR 236 310 310 THR THR A . n 
A 1 237 VAL 237 311 311 VAL VAL A . n 
A 1 238 GLN 238 312 312 GLN GLN A . n 
A 1 239 GLY 239 313 313 GLY GLY A . n 
A 1 240 ASP 240 314 314 ASP ASP A . n 
A 1 241 GLY 241 315 315 GLY GLY A . n 
A 1 242 VAL 242 316 316 VAL VAL A . n 
A 1 243 ILE 243 317 317 ILE ILE A . n 
A 1 244 VAL 244 318 318 VAL VAL A . n 
A 1 245 SER 245 319 319 SER SER A . n 
A 1 246 THR 246 320 320 THR THR A . n 
A 1 247 PRO 247 321 321 PRO PRO A . n 
A 1 248 THR 248 322 322 THR THR A . n 
A 1 249 GLY 249 323 323 GLY GLY A . n 
A 1 250 SER 250 324 324 SER SER A . n 
A 1 251 THR 251 325 325 THR THR A . n 
A 1 252 ALA 252 326 326 ALA ALA A . n 
A 1 253 TYR 253 327 327 TYR TYR A . n 
A 1 254 ALA 254 328 328 ALA ALA A . n 
A 1 255 ALA 255 329 329 ALA ALA A . n 
A 1 256 ALA 256 330 330 ALA ALA A . n 
A 1 257 ALA 257 331 331 ALA ALA A . n 
A 1 258 GLY 258 332 332 GLY GLY A . n 
A 1 259 ALA 259 333 333 ALA ALA A . n 
A 1 260 SER 260 334 334 SER SER A . n 
A 1 261 MET 261 335 335 MET MET A . n 
A 1 262 ILE 262 336 336 ILE ILE A . n 
A 1 263 HIS 263 337 337 HIS HIS A . n 
A 1 264 PRO 264 338 338 PRO PRO A . n 
A 1 265 ASN 265 339 339 ASN ASN A . n 
A 1 266 VAL 266 340 340 VAL VAL A . n 
A 1 267 PRO 267 341 341 PRO PRO A . n 
A 1 268 ALA 268 342 342 ALA ALA A . n 
A 1 269 ILE 269 343 343 ILE ILE A . n 
A 1 270 MET 270 344 344 MET MET A . n 
A 1 271 ILE 271 345 345 ILE ILE A . n 
A 1 272 THR 272 346 346 THR THR A . n 
A 1 273 PRO 273 347 347 PRO PRO A . n 
A 1 274 ILE 274 348 348 ILE ILE A . n 
A 1 275 CYS 275 349 349 CYS CYS A . n 
A 1 276 PRO 276 350 350 PRO PRO A . n 
A 1 277 HIS 277 351 351 HIS HIS A . n 
A 1 278 SER 278 352 352 SER SER A . n 
A 1 279 LEU 279 353 353 LEU LEU A . n 
A 1 280 SER 280 354 354 SER SER A . n 
A 1 281 PHE 281 355 355 PHE PHE A . n 
A 1 282 ARG 282 356 356 ARG ARG A . n 
A 1 283 PRO 283 357 357 PRO PRO A . n 
A 1 284 ILE 284 358 358 ILE ILE A . n 
A 1 285 VAL 285 359 359 VAL VAL A . n 
A 1 286 VAL 286 360 360 VAL VAL A . n 
A 1 287 PRO 287 361 361 PRO PRO A . n 
A 1 288 ALA 288 362 362 ALA ALA A . n 
A 1 289 GLY 289 363 363 GLY GLY A . n 
A 1 290 VAL 290 364 364 VAL VAL A . n 
A 1 291 GLU 291 365 365 GLU GLU A . n 
A 1 292 LEU 292 366 366 LEU LEU A . n 
A 1 293 LYS 293 367 367 LYS LYS A . n 
A 1 294 ILE 294 368 368 ILE ILE A . n 
A 1 295 MET 295 369 369 MET MET A . n 
A 1 296 LEU 296 370 370 LEU LEU A . n 
A 1 297 SER 297 371 371 SER SER A . n 
A 1 298 PRO 298 372 372 PRO PRO A . n 
A 1 299 GLU 299 373 373 GLU GLU A . n 
A 1 300 ALA 300 374 374 ALA ALA A . n 
A 1 301 ARG 301 375 375 ARG ARG A . n 
A 1 302 ASN 302 376 376 ASN ASN A . n 
A 1 303 THR 303 377 377 THR THR A . n 
A 1 304 ALA 304 378 378 ALA ALA A . n 
A 1 305 TRP 305 379 379 TRP TRP A . n 
A 1 306 VAL 306 380 380 VAL VAL A . n 
A 1 307 SER 307 381 381 SER SER A . n 
A 1 308 PHE 308 382 382 PHE PHE A . n 
A 1 309 ASP 309 383 383 ASP ASP A . n 
A 1 310 GLY 310 384 384 GLY GLY A . n 
A 1 311 ARG 311 385 385 ARG ARG A . n 
A 1 312 LYS 312 386 386 LYS LYS A . n 
A 1 313 ARG 313 387 387 ARG ARG A . n 
A 1 314 GLN 314 388 388 GLN GLN A . n 
A 1 315 GLU 315 389 389 GLU GLU A . n 
A 1 316 ILE 316 390 390 ILE ILE A . n 
A 1 317 ARG 317 391 391 ARG ARG A . n 
A 1 318 HIS 318 392 392 HIS HIS A . n 
A 1 319 GLY 319 393 393 GLY GLY A . n 
A 1 320 ASP 320 394 394 ASP ASP A . n 
A 1 321 SER 321 395 395 SER SER A . n 
A 1 322 ILE 322 396 396 ILE ILE A . n 
A 1 323 SER 323 397 397 SER SER A . n 
A 1 324 ILE 324 398 398 ILE ILE A . n 
A 1 325 THR 325 399 399 THR THR A . n 
A 1 326 THR 326 400 400 THR THR A . n 
A 1 327 SER 327 401 401 SER SER A . n 
A 1 328 THR 328 402 402 THR THR A . n 
A 1 329 TYR 329 403 403 TYR TYR A . n 
A 1 330 PRO 330 404 404 PRO PRO A . n 
A 1 331 LEU 331 405 405 LEU LEU A . n 
A 1 332 PRO 332 406 406 PRO PRO A . n 
A 1 333 SER 333 407 407 SER SER A . n 
A 1 334 ILE 334 408 408 ILE ILE A . n 
A 1 335 CYS 335 409 409 CYS CYS A . n 
A 1 336 VAL 336 410 410 VAL VAL A . n 
A 1 337 ARG 337 411 411 ARG ARG A . n 
A 1 338 ASP 338 412 412 ASP ASP A . n 
A 1 339 PRO 339 413 413 PRO PRO A . n 
A 1 340 VAL 340 414 414 VAL VAL A . n 
A 1 341 SER 341 415 415 SER SER A . n 
A 1 342 ASP 342 416 416 ASP ASP A . n 
A 1 343 TRP 343 417 417 TRP TRP A . n 
A 1 344 PHE 344 418 418 PHE PHE A . n 
A 1 345 GLU 345 419 419 GLU GLU A . n 
A 1 346 SER 346 420 420 SER SER A . n 
A 1 347 LEU 347 421 421 LEU LEU A . n 
A 1 348 ALA 348 422 422 ALA ALA A . n 
A 1 349 GLN 349 423 423 GLN GLN A . n 
A 1 350 CYS 350 424 424 CYS CYS A . n 
A 1 351 LEU 351 425 425 LEU LEU A . n 
A 1 352 HIS 352 426 426 HIS HIS A . n 
A 1 353 TRP 353 427 427 TRP TRP A . n 
A 1 354 ASN 354 428 428 ASN ASN A . n 
A 1 355 VAL 355 429 429 VAL VAL A . n 
A 1 356 ARG 356 430 ?   ?   ?   A . n 
A 1 357 LYS 357 431 ?   ?   ?   A . n 
A 1 358 LYS 358 432 ?   ?   ?   A . n 
A 1 359 GLN 359 433 ?   ?   ?   A . n 
A 1 360 ALA 360 434 ?   ?   ?   A . n 
A 1 361 HIS 361 435 ?   ?   ?   A . n 
A 1 362 PHE 362 436 ?   ?   ?   A . n 
A 1 363 GLU 363 437 ?   ?   ?   A . n 
A 1 364 LEU 364 438 ?   ?   ?   A . n 
A 1 365 GLY 365 439 ?   ?   ?   A . n 
A 1 366 LEU 366 440 ?   ?   ?   A . n 
A 1 367 GLU 367 441 ?   ?   ?   A . n 
A 1 368 HIS 368 442 ?   ?   ?   A . n 
A 1 369 HIS 369 443 ?   ?   ?   A . n 
A 1 370 HIS 370 444 ?   ?   ?   A . n 
A 1 371 HIS 371 445 ?   ?   ?   A . n 
A 1 372 HIS 372 446 ?   ?   ?   A . n 
A 1 373 HIS 373 447 ?   ?   ?   A . n 
B 1 1   MET 1   75  ?   ?   ?   B . n 
B 1 2   PRO 2   76  ?   ?   ?   B . n 
B 1 3   SER 3   77  ?   ?   ?   B . n 
B 1 4   PRO 4   78  ?   ?   ?   B . n 
B 1 5   VAL 5   79  ?   ?   ?   B . n 
B 1 6   THR 6   80  ?   ?   ?   B . n 
B 1 7   THR 7   81  ?   ?   ?   B . n 
B 1 8   PHE 8   82  ?   ?   ?   B . n 
B 1 9   GLY 9   83  ?   ?   ?   B . n 
B 1 10  PRO 10  84  ?   ?   ?   B . n 
B 1 11  LYS 11  85  ?   ?   ?   B . n 
B 1 12  ALA 12  86  ?   ?   ?   B . n 
B 1 13  THR 13  87  ?   ?   ?   B . n 
B 1 14  VAL 14  88  ?   ?   ?   B . n 
B 1 15  GLU 15  89  ?   ?   ?   B . n 
B 1 16  THR 16  90  ?   ?   ?   B . n 
B 1 17  GLN 17  91  ?   ?   ?   B . n 
B 1 18  ASP 18  92  ?   ?   ?   B . n 
B 1 19  PRO 19  93  ?   ?   ?   B . n 
B 1 20  ALA 20  94  ?   ?   ?   B . n 
B 1 21  SER 21  95  95  SER SER B . n 
B 1 22  VAL 22  96  96  VAL VAL B . n 
B 1 23  ARG 23  97  97  ARG ARG B . n 
B 1 24  LEU 24  98  98  LEU LEU B . n 
B 1 25  THR 25  99  99  THR THR B . n 
B 1 26  TRP 26  100 100 TRP TRP B . n 
B 1 27  ASN 27  101 101 ASN ASN B . n 
B 1 28  LYS 28  102 102 LYS LYS B . n 
B 1 29  SER 29  103 103 SER SER B . n 
B 1 30  PRO 30  104 104 PRO PRO B . n 
B 1 31  LYS 31  105 105 LYS LYS B . n 
B 1 32  SER 32  106 106 SER SER B . n 
B 1 33  VAL 33  107 107 VAL VAL B . n 
B 1 34  LEU 34  108 108 LEU LEU B . n 
B 1 35  VAL 35  109 109 VAL VAL B . n 
B 1 36  ILE 36  110 110 ILE ILE B . n 
B 1 37  LYS 37  111 111 LYS LYS B . n 
B 1 38  LYS 38  112 112 LYS LYS B . n 
B 1 39  MET 39  113 113 MET MET B . n 
B 1 40  ARG 40  114 114 ARG ARG B . n 
B 1 41  ASP 41  115 115 ASP ASP B . n 
B 1 42  ALA 42  116 116 ALA ALA B . n 
B 1 43  SER 43  117 117 SER SER B . n 
B 1 44  LEU 44  118 118 LEU LEU B . n 
B 1 45  LEU 45  119 119 LEU LEU B . n 
B 1 46  GLN 46  120 120 GLN GLN B . n 
B 1 47  PRO 47  121 121 PRO PRO B . n 
B 1 48  PHE 48  122 122 PHE PHE B . n 
B 1 49  LYS 49  123 123 LYS LYS B . n 
B 1 50  GLU 50  124 124 GLU GLU B . n 
B 1 51  LEU 51  125 125 LEU LEU B . n 
B 1 52  CYS 52  126 126 CYS CYS B . n 
B 1 53  THR 53  127 127 THR THR B . n 
B 1 54  HIS 54  128 128 HIS HIS B . n 
B 1 55  LEU 55  129 129 LEU LEU B . n 
B 1 56  MET 56  130 130 MET MET B . n 
B 1 57  GLU 57  131 131 GLU GLU B . n 
B 1 58  GLU 58  132 132 GLU GLU B . n 
B 1 59  ASN 59  133 133 ASN ASN B . n 
B 1 60  MET 60  134 134 MET MET B . n 
B 1 61  ILE 61  135 135 ILE ILE B . n 
B 1 62  VAL 62  136 136 VAL VAL B . n 
B 1 63  TYR 63  137 137 TYR TYR B . n 
B 1 64  VAL 64  138 138 VAL VAL B . n 
B 1 65  GLU 65  139 139 GLU GLU B . n 
B 1 66  LYS 66  140 140 LYS LYS B . n 
B 1 67  LYS 67  141 141 LYS LYS B . n 
B 1 68  VAL 68  142 142 VAL VAL B . n 
B 1 69  LEU 69  143 143 LEU LEU B . n 
B 1 70  GLU 70  144 144 GLU GLU B . n 
B 1 71  ASP 71  145 145 ASP ASP B . n 
B 1 72  PRO 72  146 146 PRO PRO B . n 
B 1 73  ALA 73  147 147 ALA ALA B . n 
B 1 74  ILE 74  148 148 ILE ILE B . n 
B 1 75  ALA 75  149 149 ALA ALA B . n 
B 1 76  SER 76  150 150 SER SER B . n 
B 1 77  ASP 77  151 151 ASP ASP B . n 
B 1 78  GLU 78  152 152 GLU GLU B . n 
B 1 79  SER 79  153 153 SER SER B . n 
B 1 80  PHE 80  154 154 PHE PHE B . n 
B 1 81  GLY 81  155 155 GLY GLY B . n 
B 1 82  ALA 82  156 156 ALA ALA B . n 
B 1 83  VAL 83  157 157 VAL VAL B . n 
B 1 84  LYS 84  158 158 LYS LYS B . n 
B 1 85  LYS 85  159 159 LYS LYS B . n 
B 1 86  LYS 86  160 160 LYS LYS B . n 
B 1 87  PHE 87  161 161 PHE PHE B . n 
B 1 88  THR 88  162 162 THR THR B . n 
B 1 89  THR 89  163 ?   ?   ?   B . n 
B 1 90  PHE 90  164 ?   ?   ?   B . n 
B 1 91  ARG 91  165 ?   ?   ?   B . n 
B 1 92  GLU 92  166 ?   ?   ?   B . n 
B 1 93  ASP 93  167 ?   ?   ?   B . n 
B 1 94  TYR 94  168 ?   ?   ?   B . n 
B 1 95  ASP 95  169 ?   ?   ?   B . n 
B 1 96  ASP 96  170 ?   ?   ?   B . n 
B 1 97  ILE 97  171 ?   ?   ?   B . n 
B 1 98  SER 98  172 ?   ?   ?   B . n 
B 1 99  ASN 99  173 ?   ?   ?   B . n 
B 1 100 GLN 100 174 174 GLN GLN B . n 
B 1 101 ILE 101 175 175 ILE ILE B . n 
B 1 102 ASP 102 176 176 ASP ASP B . n 
B 1 103 PHE 103 177 177 PHE PHE B . n 
B 1 104 ILE 104 178 178 ILE ILE B . n 
B 1 105 ILE 105 179 179 ILE ILE B . n 
B 1 106 CYS 106 180 180 CYS CYS B . n 
B 1 107 LEU 107 181 181 LEU LEU B . n 
B 1 108 GLY 108 182 182 GLY GLY B . n 
B 1 109 GLY 109 183 183 GLY GLY B . n 
B 1 110 ASP 110 184 184 ASP ASP B . n 
B 1 111 GLY 111 185 185 GLY GLY B . n 
B 1 112 THR 112 186 186 THR THR B . n 
B 1 113 LEU 113 187 187 LEU LEU B . n 
B 1 114 LEU 114 188 188 LEU LEU B . n 
B 1 115 TYR 115 189 189 TYR TYR B . n 
B 1 116 ALA 116 190 190 ALA ALA B . n 
B 1 117 SER 117 191 191 SER SER B . n 
B 1 118 SER 118 192 192 SER SER B . n 
B 1 119 LEU 119 193 193 LEU LEU B . n 
B 1 120 PHE 120 194 194 PHE PHE B . n 
B 1 121 GLN 121 195 195 GLN GLN B . n 
B 1 122 GLY 122 196 196 GLY GLY B . n 
B 1 123 SER 123 197 197 SER SER B . n 
B 1 124 VAL 124 198 198 VAL VAL B . n 
B 1 125 PRO 125 199 199 PRO PRO B . n 
B 1 126 PRO 126 200 200 PRO PRO B . n 
B 1 127 VAL 127 201 201 VAL VAL B . n 
B 1 128 MET 128 202 202 MET MET B . n 
B 1 129 ALA 129 203 203 ALA ALA B . n 
B 1 130 PHE 130 204 204 PHE PHE B . n 
B 1 131 HIS 131 205 205 HIS HIS B . n 
B 1 132 LEU 132 206 206 LEU LEU B . n 
B 1 133 GLY 133 207 207 GLY GLY B . n 
B 1 134 SER 134 208 208 SER SER B . n 
B 1 135 LEU 135 209 209 LEU LEU B . n 
B 1 136 GLY 136 210 210 GLY GLY B . n 
B 1 137 PHE 137 211 211 PHE PHE B . n 
B 1 138 LEU 138 212 212 LEU LEU B . n 
B 1 139 THR 139 213 213 THR THR B . n 
B 1 140 PRO 140 214 214 PRO PRO B . n 
B 1 141 PHE 141 215 215 PHE PHE B . n 
B 1 142 SER 142 216 216 SER SER B . n 
B 1 143 PHE 143 217 217 PHE PHE B . n 
B 1 144 GLU 144 218 218 GLU GLU B . n 
B 1 145 ASN 145 219 219 ASN ASN B . n 
B 1 146 PHE 146 220 220 PHE PHE B . n 
B 1 147 GLN 147 221 221 GLN GLN B . n 
B 1 148 SER 148 222 222 SER SER B . n 
B 1 149 GLN 149 223 223 GLN GLN B . n 
B 1 150 VAL 150 224 224 VAL VAL B . n 
B 1 151 THR 151 225 225 THR THR B . n 
B 1 152 GLN 152 226 226 GLN GLN B . n 
B 1 153 VAL 153 227 227 VAL VAL B . n 
B 1 154 ILE 154 228 228 ILE ILE B . n 
B 1 155 GLU 155 229 229 GLU GLU B . n 
B 1 156 GLY 156 230 230 GLY GLY B . n 
B 1 157 ASN 157 231 231 ASN ASN B . n 
B 1 158 ALA 158 232 232 ALA ALA B . n 
B 1 159 ALA 159 233 233 ALA ALA B . n 
B 1 160 VAL 160 234 234 VAL VAL B . n 
B 1 161 VAL 161 235 235 VAL VAL B . n 
B 1 162 LEU 162 236 236 LEU LEU B . n 
B 1 163 ARG 163 237 237 ARG ARG B . n 
B 1 164 SER 164 238 238 SER SER B . n 
B 1 165 ARG 165 239 239 ARG ARG B . n 
B 1 166 LEU 166 240 240 LEU LEU B . n 
B 1 167 LYS 167 241 241 LYS LYS B . n 
B 1 168 VAL 168 242 242 VAL VAL B . n 
B 1 169 ARG 169 243 243 ARG ARG B . n 
B 1 170 VAL 170 244 244 VAL VAL B . n 
B 1 171 VAL 171 245 245 VAL VAL B . n 
B 1 172 LYS 172 246 246 LYS LYS B . n 
B 1 173 GLU 173 247 ?   ?   ?   B . n 
B 1 174 LEU 174 248 ?   ?   ?   B . n 
B 1 175 ARG 175 249 ?   ?   ?   B . n 
B 1 176 GLY 176 250 ?   ?   ?   B . n 
B 1 177 LYS 177 251 ?   ?   ?   B . n 
B 1 178 LYS 178 252 ?   ?   ?   B . n 
B 1 179 THR 179 253 ?   ?   ?   B . n 
B 1 180 ALA 180 254 ?   ?   ?   B . n 
B 1 181 VAL 181 255 ?   ?   ?   B . n 
B 1 182 HIS 182 256 ?   ?   ?   B . n 
B 1 183 ASN 183 257 ?   ?   ?   B . n 
B 1 184 GLY 184 258 ?   ?   ?   B . n 
B 1 185 LEU 185 259 ?   ?   ?   B . n 
B 1 186 GLY 186 260 ?   ?   ?   B . n 
B 1 187 GLU 187 261 ?   ?   ?   B . n 
B 1 188 ASN 188 262 ?   ?   ?   B . n 
B 1 189 GLY 189 263 ?   ?   ?   B . n 
B 1 190 SER 190 264 ?   ?   ?   B . n 
B 1 191 GLN 191 265 ?   ?   ?   B . n 
B 1 192 ALA 192 266 ?   ?   ?   B . n 
B 1 193 ALA 193 267 ?   ?   ?   B . n 
B 1 194 GLY 194 268 ?   ?   ?   B . n 
B 1 195 LEU 195 269 ?   ?   ?   B . n 
B 1 196 ASP 196 270 ?   ?   ?   B . n 
B 1 197 MET 197 271 ?   ?   ?   B . n 
B 1 198 ASP 198 272 ?   ?   ?   B . n 
B 1 199 VAL 199 273 ?   ?   ?   B . n 
B 1 200 GLY 200 274 ?   ?   ?   B . n 
B 1 201 LYS 201 275 ?   ?   ?   B . n 
B 1 202 GLN 202 276 ?   ?   ?   B . n 
B 1 203 ALA 203 277 277 ALA ALA B . n 
B 1 204 MET 204 278 278 MET MET B . n 
B 1 205 GLN 205 279 279 GLN GLN B . n 
B 1 206 TYR 206 280 280 TYR TYR B . n 
B 1 207 GLN 207 281 281 GLN GLN B . n 
B 1 208 VAL 208 282 282 VAL VAL B . n 
B 1 209 LEU 209 283 283 LEU LEU B . n 
B 1 210 ASN 210 284 284 ASN ASN B . n 
B 1 211 GLU 211 285 285 GLU GLU B . n 
B 1 212 VAL 212 286 286 VAL VAL B . n 
B 1 213 VAL 213 287 287 VAL VAL B . n 
B 1 214 ILE 214 288 288 ILE ILE B . n 
B 1 215 ASP 215 289 289 ASP ASP B . n 
B 1 216 ARG 216 290 290 ARG ARG B . n 
B 1 217 GLY 217 291 291 GLY GLY B . n 
B 1 218 PRO 218 292 292 PRO PRO B . n 
B 1 219 SER 219 293 293 SER SER B . n 
B 1 220 SER 220 294 294 SER SER B . n 
B 1 221 TYR 221 295 ?   ?   ?   B . n 
B 1 222 LEU 222 296 296 LEU LEU B . n 
B 1 223 SER 223 297 297 SER SER B . n 
B 1 224 ASN 224 298 298 ASN ASN B . n 
B 1 225 VAL 225 299 299 VAL VAL B . n 
B 1 226 ASP 226 300 300 ASP ASP B . n 
B 1 227 VAL 227 301 301 VAL VAL B . n 
B 1 228 TYR 228 302 302 TYR TYR B . n 
B 1 229 LEU 229 303 303 LEU LEU B . n 
B 1 230 ASP 230 304 304 ASP ASP B . n 
B 1 231 GLY 231 305 305 GLY GLY B . n 
B 1 232 HIS 232 306 306 HIS HIS B . n 
B 1 233 LEU 233 307 307 LEU LEU B . n 
B 1 234 ILE 234 308 308 ILE ILE B . n 
B 1 235 THR 235 309 309 THR THR B . n 
B 1 236 THR 236 310 310 THR THR B . n 
B 1 237 VAL 237 311 311 VAL VAL B . n 
B 1 238 GLN 238 312 312 GLN GLN B . n 
B 1 239 GLY 239 313 313 GLY GLY B . n 
B 1 240 ASP 240 314 314 ASP ASP B . n 
B 1 241 GLY 241 315 315 GLY GLY B . n 
B 1 242 VAL 242 316 316 VAL VAL B . n 
B 1 243 ILE 243 317 317 ILE ILE B . n 
B 1 244 VAL 244 318 318 VAL VAL B . n 
B 1 245 SER 245 319 319 SER SER B . n 
B 1 246 THR 246 320 320 THR THR B . n 
B 1 247 PRO 247 321 321 PRO PRO B . n 
B 1 248 THR 248 322 322 THR THR B . n 
B 1 249 GLY 249 323 323 GLY GLY B . n 
B 1 250 SER 250 324 324 SER SER B . n 
B 1 251 THR 251 325 325 THR THR B . n 
B 1 252 ALA 252 326 326 ALA ALA B . n 
B 1 253 TYR 253 327 327 TYR TYR B . n 
B 1 254 ALA 254 328 328 ALA ALA B . n 
B 1 255 ALA 255 329 329 ALA ALA B . n 
B 1 256 ALA 256 330 330 ALA ALA B . n 
B 1 257 ALA 257 331 331 ALA ALA B . n 
B 1 258 GLY 258 332 332 GLY GLY B . n 
B 1 259 ALA 259 333 333 ALA ALA B . n 
B 1 260 SER 260 334 334 SER SER B . n 
B 1 261 MET 261 335 335 MET MET B . n 
B 1 262 ILE 262 336 336 ILE ILE B . n 
B 1 263 HIS 263 337 337 HIS HIS B . n 
B 1 264 PRO 264 338 338 PRO PRO B . n 
B 1 265 ASN 265 339 339 ASN ASN B . n 
B 1 266 VAL 266 340 340 VAL VAL B . n 
B 1 267 PRO 267 341 341 PRO PRO B . n 
B 1 268 ALA 268 342 342 ALA ALA B . n 
B 1 269 ILE 269 343 343 ILE ILE B . n 
B 1 270 MET 270 344 344 MET MET B . n 
B 1 271 ILE 271 345 345 ILE ILE B . n 
B 1 272 THR 272 346 346 THR THR B . n 
B 1 273 PRO 273 347 347 PRO PRO B . n 
B 1 274 ILE 274 348 348 ILE ILE B . n 
B 1 275 CYS 275 349 349 CYS CYS B . n 
B 1 276 PRO 276 350 350 PRO PRO B . n 
B 1 277 HIS 277 351 351 HIS HIS B . n 
B 1 278 SER 278 352 352 SER SER B . n 
B 1 279 LEU 279 353 353 LEU LEU B . n 
B 1 280 SER 280 354 354 SER SER B . n 
B 1 281 PHE 281 355 355 PHE PHE B . n 
B 1 282 ARG 282 356 356 ARG ARG B . n 
B 1 283 PRO 283 357 357 PRO PRO B . n 
B 1 284 ILE 284 358 358 ILE ILE B . n 
B 1 285 VAL 285 359 359 VAL VAL B . n 
B 1 286 VAL 286 360 360 VAL VAL B . n 
B 1 287 PRO 287 361 361 PRO PRO B . n 
B 1 288 ALA 288 362 362 ALA ALA B . n 
B 1 289 GLY 289 363 363 GLY GLY B . n 
B 1 290 VAL 290 364 364 VAL VAL B . n 
B 1 291 GLU 291 365 365 GLU GLU B . n 
B 1 292 LEU 292 366 366 LEU LEU B . n 
B 1 293 LYS 293 367 367 LYS LYS B . n 
B 1 294 ILE 294 368 368 ILE ILE B . n 
B 1 295 MET 295 369 369 MET MET B . n 
B 1 296 LEU 296 370 370 LEU LEU B . n 
B 1 297 SER 297 371 371 SER SER B . n 
B 1 298 PRO 298 372 372 PRO PRO B . n 
B 1 299 GLU 299 373 373 GLU GLU B . n 
B 1 300 ALA 300 374 374 ALA ALA B . n 
B 1 301 ARG 301 375 375 ARG ARG B . n 
B 1 302 ASN 302 376 376 ASN ASN B . n 
B 1 303 THR 303 377 377 THR THR B . n 
B 1 304 ALA 304 378 378 ALA ALA B . n 
B 1 305 TRP 305 379 379 TRP TRP B . n 
B 1 306 VAL 306 380 380 VAL VAL B . n 
B 1 307 SER 307 381 381 SER SER B . n 
B 1 308 PHE 308 382 382 PHE PHE B . n 
B 1 309 ASP 309 383 383 ASP ASP B . n 
B 1 310 GLY 310 384 384 GLY GLY B . n 
B 1 311 ARG 311 385 385 ARG ARG B . n 
B 1 312 LYS 312 386 386 LYS LYS B . n 
B 1 313 ARG 313 387 387 ARG ARG B . n 
B 1 314 GLN 314 388 388 GLN GLN B . n 
B 1 315 GLU 315 389 389 GLU GLU B . n 
B 1 316 ILE 316 390 390 ILE ILE B . n 
B 1 317 ARG 317 391 391 ARG ARG B . n 
B 1 318 HIS 318 392 392 HIS HIS B . n 
B 1 319 GLY 319 393 393 GLY GLY B . n 
B 1 320 ASP 320 394 394 ASP ASP B . n 
B 1 321 SER 321 395 395 SER SER B . n 
B 1 322 ILE 322 396 396 ILE ILE B . n 
B 1 323 SER 323 397 397 SER SER B . n 
B 1 324 ILE 324 398 398 ILE ILE B . n 
B 1 325 THR 325 399 399 THR THR B . n 
B 1 326 THR 326 400 400 THR THR B . n 
B 1 327 SER 327 401 401 SER SER B . n 
B 1 328 THR 328 402 402 THR THR B . n 
B 1 329 TYR 329 403 403 TYR TYR B . n 
B 1 330 PRO 330 404 404 PRO PRO B . n 
B 1 331 LEU 331 405 405 LEU LEU B . n 
B 1 332 PRO 332 406 406 PRO PRO B . n 
B 1 333 SER 333 407 407 SER SER B . n 
B 1 334 ILE 334 408 408 ILE ILE B . n 
B 1 335 CYS 335 409 409 CYS CYS B . n 
B 1 336 VAL 336 410 410 VAL VAL B . n 
B 1 337 ARG 337 411 411 ARG ARG B . n 
B 1 338 ASP 338 412 412 ASP ASP B . n 
B 1 339 PRO 339 413 413 PRO PRO B . n 
B 1 340 VAL 340 414 414 VAL VAL B . n 
B 1 341 SER 341 415 415 SER SER B . n 
B 1 342 ASP 342 416 416 ASP ASP B . n 
B 1 343 TRP 343 417 417 TRP TRP B . n 
B 1 344 PHE 344 418 418 PHE PHE B . n 
B 1 345 GLU 345 419 419 GLU GLU B . n 
B 1 346 SER 346 420 420 SER SER B . n 
B 1 347 LEU 347 421 421 LEU LEU B . n 
B 1 348 ALA 348 422 422 ALA ALA B . n 
B 1 349 GLN 349 423 423 GLN GLN B . n 
B 1 350 CYS 350 424 424 CYS CYS B . n 
B 1 351 LEU 351 425 425 LEU LEU B . n 
B 1 352 HIS 352 426 426 HIS HIS B . n 
B 1 353 TRP 353 427 427 TRP TRP B . n 
B 1 354 ASN 354 428 428 ASN ASN B . n 
B 1 355 VAL 355 429 429 VAL VAL B . n 
B 1 356 ARG 356 430 ?   ?   ?   B . n 
B 1 357 LYS 357 431 ?   ?   ?   B . n 
B 1 358 LYS 358 432 ?   ?   ?   B . n 
B 1 359 GLN 359 433 ?   ?   ?   B . n 
B 1 360 ALA 360 434 ?   ?   ?   B . n 
B 1 361 HIS 361 435 ?   ?   ?   B . n 
B 1 362 PHE 362 436 ?   ?   ?   B . n 
B 1 363 GLU 363 437 ?   ?   ?   B . n 
B 1 364 LEU 364 438 ?   ?   ?   B . n 
B 1 365 GLY 365 439 ?   ?   ?   B . n 
B 1 366 LEU 366 440 ?   ?   ?   B . n 
B 1 367 GLU 367 441 ?   ?   ?   B . n 
B 1 368 HIS 368 442 ?   ?   ?   B . n 
B 1 369 HIS 369 443 ?   ?   ?   B . n 
B 1 370 HIS 370 444 ?   ?   ?   B . n 
B 1 371 HIS 371 445 ?   ?   ?   B . n 
B 1 372 HIS 372 446 ?   ?   ?   B . n 
B 1 373 HIS 373 447 ?   ?   ?   B . n 
C 1 1   MET 1   75  ?   ?   ?   C . n 
C 1 2   PRO 2   76  ?   ?   ?   C . n 
C 1 3   SER 3   77  ?   ?   ?   C . n 
C 1 4   PRO 4   78  ?   ?   ?   C . n 
C 1 5   VAL 5   79  ?   ?   ?   C . n 
C 1 6   THR 6   80  ?   ?   ?   C . n 
C 1 7   THR 7   81  ?   ?   ?   C . n 
C 1 8   PHE 8   82  ?   ?   ?   C . n 
C 1 9   GLY 9   83  ?   ?   ?   C . n 
C 1 10  PRO 10  84  ?   ?   ?   C . n 
C 1 11  LYS 11  85  ?   ?   ?   C . n 
C 1 12  ALA 12  86  ?   ?   ?   C . n 
C 1 13  THR 13  87  ?   ?   ?   C . n 
C 1 14  VAL 14  88  ?   ?   ?   C . n 
C 1 15  GLU 15  89  ?   ?   ?   C . n 
C 1 16  THR 16  90  ?   ?   ?   C . n 
C 1 17  GLN 17  91  ?   ?   ?   C . n 
C 1 18  ASP 18  92  ?   ?   ?   C . n 
C 1 19  PRO 19  93  ?   ?   ?   C . n 
C 1 20  ALA 20  94  ?   ?   ?   C . n 
C 1 21  SER 21  95  ?   ?   ?   C . n 
C 1 22  VAL 22  96  96  VAL VAL C . n 
C 1 23  ARG 23  97  97  ARG ARG C . n 
C 1 24  LEU 24  98  98  LEU LEU C . n 
C 1 25  THR 25  99  99  THR THR C . n 
C 1 26  TRP 26  100 100 TRP TRP C . n 
C 1 27  ASN 27  101 101 ASN ASN C . n 
C 1 28  LYS 28  102 102 LYS LYS C . n 
C 1 29  SER 29  103 103 SER SER C . n 
C 1 30  PRO 30  104 104 PRO PRO C . n 
C 1 31  LYS 31  105 105 LYS LYS C . n 
C 1 32  SER 32  106 106 SER SER C . n 
C 1 33  VAL 33  107 107 VAL VAL C . n 
C 1 34  LEU 34  108 108 LEU LEU C . n 
C 1 35  VAL 35  109 109 VAL VAL C . n 
C 1 36  ILE 36  110 110 ILE ILE C . n 
C 1 37  LYS 37  111 111 LYS LYS C . n 
C 1 38  LYS 38  112 112 LYS LYS C . n 
C 1 39  MET 39  113 113 MET MET C . n 
C 1 40  ARG 40  114 114 ARG ARG C . n 
C 1 41  ASP 41  115 115 ASP ASP C . n 
C 1 42  ALA 42  116 116 ALA ALA C . n 
C 1 43  SER 43  117 117 SER SER C . n 
C 1 44  LEU 44  118 118 LEU LEU C . n 
C 1 45  LEU 45  119 119 LEU LEU C . n 
C 1 46  GLN 46  120 120 GLN GLN C . n 
C 1 47  PRO 47  121 121 PRO PRO C . n 
C 1 48  PHE 48  122 122 PHE PHE C . n 
C 1 49  LYS 49  123 123 LYS LYS C . n 
C 1 50  GLU 50  124 124 GLU GLU C . n 
C 1 51  LEU 51  125 125 LEU LEU C . n 
C 1 52  CYS 52  126 126 CYS CYS C . n 
C 1 53  THR 53  127 127 THR THR C . n 
C 1 54  HIS 54  128 128 HIS HIS C . n 
C 1 55  LEU 55  129 129 LEU LEU C . n 
C 1 56  MET 56  130 130 MET MET C . n 
C 1 57  GLU 57  131 131 GLU GLU C . n 
C 1 58  GLU 58  132 132 GLU GLU C . n 
C 1 59  ASN 59  133 133 ASN ASN C . n 
C 1 60  MET 60  134 134 MET MET C . n 
C 1 61  ILE 61  135 135 ILE ILE C . n 
C 1 62  VAL 62  136 136 VAL VAL C . n 
C 1 63  TYR 63  137 137 TYR TYR C . n 
C 1 64  VAL 64  138 138 VAL VAL C . n 
C 1 65  GLU 65  139 139 GLU GLU C . n 
C 1 66  LYS 66  140 140 LYS LYS C . n 
C 1 67  LYS 67  141 141 LYS LYS C . n 
C 1 68  VAL 68  142 142 VAL VAL C . n 
C 1 69  LEU 69  143 143 LEU LEU C . n 
C 1 70  GLU 70  144 144 GLU GLU C . n 
C 1 71  ASP 71  145 145 ASP ASP C . n 
C 1 72  PRO 72  146 146 PRO PRO C . n 
C 1 73  ALA 73  147 147 ALA ALA C . n 
C 1 74  ILE 74  148 148 ILE ILE C . n 
C 1 75  ALA 75  149 149 ALA ALA C . n 
C 1 76  SER 76  150 150 SER SER C . n 
C 1 77  ASP 77  151 151 ASP ASP C . n 
C 1 78  GLU 78  152 152 GLU GLU C . n 
C 1 79  SER 79  153 153 SER SER C . n 
C 1 80  PHE 80  154 154 PHE PHE C . n 
C 1 81  GLY 81  155 155 GLY GLY C . n 
C 1 82  ALA 82  156 156 ALA ALA C . n 
C 1 83  VAL 83  157 157 VAL VAL C . n 
C 1 84  LYS 84  158 158 LYS LYS C . n 
C 1 85  LYS 85  159 159 LYS LYS C . n 
C 1 86  LYS 86  160 160 LYS LYS C . n 
C 1 87  PHE 87  161 161 PHE PHE C . n 
C 1 88  THR 88  162 162 THR THR C . n 
C 1 89  THR 89  163 ?   ?   ?   C . n 
C 1 90  PHE 90  164 ?   ?   ?   C . n 
C 1 91  ARG 91  165 ?   ?   ?   C . n 
C 1 92  GLU 92  166 ?   ?   ?   C . n 
C 1 93  ASP 93  167 ?   ?   ?   C . n 
C 1 94  TYR 94  168 ?   ?   ?   C . n 
C 1 95  ASP 95  169 ?   ?   ?   C . n 
C 1 96  ASP 96  170 ?   ?   ?   C . n 
C 1 97  ILE 97  171 ?   ?   ?   C . n 
C 1 98  SER 98  172 ?   ?   ?   C . n 
C 1 99  ASN 99  173 ?   ?   ?   C . n 
C 1 100 GLN 100 174 174 GLN GLN C . n 
C 1 101 ILE 101 175 175 ILE ILE C . n 
C 1 102 ASP 102 176 176 ASP ASP C . n 
C 1 103 PHE 103 177 177 PHE PHE C . n 
C 1 104 ILE 104 178 178 ILE ILE C . n 
C 1 105 ILE 105 179 179 ILE ILE C . n 
C 1 106 CYS 106 180 180 CYS CYS C . n 
C 1 107 LEU 107 181 181 LEU LEU C . n 
C 1 108 GLY 108 182 182 GLY GLY C . n 
C 1 109 GLY 109 183 183 GLY GLY C . n 
C 1 110 ASP 110 184 184 ASP ASP C . n 
C 1 111 GLY 111 185 185 GLY GLY C . n 
C 1 112 THR 112 186 186 THR THR C . n 
C 1 113 LEU 113 187 187 LEU LEU C . n 
C 1 114 LEU 114 188 188 LEU LEU C . n 
C 1 115 TYR 115 189 189 TYR TYR C . n 
C 1 116 ALA 116 190 190 ALA ALA C . n 
C 1 117 SER 117 191 191 SER SER C . n 
C 1 118 SER 118 192 192 SER SER C . n 
C 1 119 LEU 119 193 193 LEU LEU C . n 
C 1 120 PHE 120 194 194 PHE PHE C . n 
C 1 121 GLN 121 195 195 GLN GLN C . n 
C 1 122 GLY 122 196 196 GLY GLY C . n 
C 1 123 SER 123 197 197 SER SER C . n 
C 1 124 VAL 124 198 198 VAL VAL C . n 
C 1 125 PRO 125 199 199 PRO PRO C . n 
C 1 126 PRO 126 200 200 PRO PRO C . n 
C 1 127 VAL 127 201 201 VAL VAL C . n 
C 1 128 MET 128 202 202 MET MET C . n 
C 1 129 ALA 129 203 203 ALA ALA C . n 
C 1 130 PHE 130 204 204 PHE PHE C . n 
C 1 131 HIS 131 205 205 HIS HIS C . n 
C 1 132 LEU 132 206 206 LEU LEU C . n 
C 1 133 GLY 133 207 207 GLY GLY C . n 
C 1 134 SER 134 208 208 SER SER C . n 
C 1 135 LEU 135 209 209 LEU LEU C . n 
C 1 136 GLY 136 210 210 GLY GLY C . n 
C 1 137 PHE 137 211 211 PHE PHE C . n 
C 1 138 LEU 138 212 212 LEU LEU C . n 
C 1 139 THR 139 213 213 THR THR C . n 
C 1 140 PRO 140 214 214 PRO PRO C . n 
C 1 141 PHE 141 215 215 PHE PHE C . n 
C 1 142 SER 142 216 216 SER SER C . n 
C 1 143 PHE 143 217 217 PHE PHE C . n 
C 1 144 GLU 144 218 218 GLU GLU C . n 
C 1 145 ASN 145 219 219 ASN ASN C . n 
C 1 146 PHE 146 220 220 PHE PHE C . n 
C 1 147 GLN 147 221 221 GLN GLN C . n 
C 1 148 SER 148 222 222 SER SER C . n 
C 1 149 GLN 149 223 223 GLN GLN C . n 
C 1 150 VAL 150 224 224 VAL VAL C . n 
C 1 151 THR 151 225 225 THR THR C . n 
C 1 152 GLN 152 226 226 GLN GLN C . n 
C 1 153 VAL 153 227 227 VAL VAL C . n 
C 1 154 ILE 154 228 228 ILE ILE C . n 
C 1 155 GLU 155 229 229 GLU GLU C . n 
C 1 156 GLY 156 230 230 GLY GLY C . n 
C 1 157 ASN 157 231 231 ASN ASN C . n 
C 1 158 ALA 158 232 232 ALA ALA C . n 
C 1 159 ALA 159 233 233 ALA ALA C . n 
C 1 160 VAL 160 234 234 VAL VAL C . n 
C 1 161 VAL 161 235 235 VAL VAL C . n 
C 1 162 LEU 162 236 236 LEU LEU C . n 
C 1 163 ARG 163 237 237 ARG ARG C . n 
C 1 164 SER 164 238 238 SER SER C . n 
C 1 165 ARG 165 239 239 ARG ARG C . n 
C 1 166 LEU 166 240 240 LEU LEU C . n 
C 1 167 LYS 167 241 241 LYS LYS C . n 
C 1 168 VAL 168 242 242 VAL VAL C . n 
C 1 169 ARG 169 243 243 ARG ARG C . n 
C 1 170 VAL 170 244 244 VAL VAL C . n 
C 1 171 VAL 171 245 245 VAL VAL C . n 
C 1 172 LYS 172 246 246 LYS LYS C . n 
C 1 173 GLU 173 247 247 GLU GLU C . n 
C 1 174 LEU 174 248 ?   ?   ?   C . n 
C 1 175 ARG 175 249 ?   ?   ?   C . n 
C 1 176 GLY 176 250 ?   ?   ?   C . n 
C 1 177 LYS 177 251 ?   ?   ?   C . n 
C 1 178 LYS 178 252 ?   ?   ?   C . n 
C 1 179 THR 179 253 ?   ?   ?   C . n 
C 1 180 ALA 180 254 ?   ?   ?   C . n 
C 1 181 VAL 181 255 ?   ?   ?   C . n 
C 1 182 HIS 182 256 ?   ?   ?   C . n 
C 1 183 ASN 183 257 ?   ?   ?   C . n 
C 1 184 GLY 184 258 ?   ?   ?   C . n 
C 1 185 LEU 185 259 ?   ?   ?   C . n 
C 1 186 GLY 186 260 ?   ?   ?   C . n 
C 1 187 GLU 187 261 ?   ?   ?   C . n 
C 1 188 ASN 188 262 ?   ?   ?   C . n 
C 1 189 GLY 189 263 ?   ?   ?   C . n 
C 1 190 SER 190 264 ?   ?   ?   C . n 
C 1 191 GLN 191 265 ?   ?   ?   C . n 
C 1 192 ALA 192 266 ?   ?   ?   C . n 
C 1 193 ALA 193 267 ?   ?   ?   C . n 
C 1 194 GLY 194 268 ?   ?   ?   C . n 
C 1 195 LEU 195 269 ?   ?   ?   C . n 
C 1 196 ASP 196 270 ?   ?   ?   C . n 
C 1 197 MET 197 271 ?   ?   ?   C . n 
C 1 198 ASP 198 272 ?   ?   ?   C . n 
C 1 199 VAL 199 273 ?   ?   ?   C . n 
C 1 200 GLY 200 274 ?   ?   ?   C . n 
C 1 201 LYS 201 275 ?   ?   ?   C . n 
C 1 202 GLN 202 276 ?   ?   ?   C . n 
C 1 203 ALA 203 277 277 ALA ALA C . n 
C 1 204 MET 204 278 278 MET MET C . n 
C 1 205 GLN 205 279 279 GLN GLN C . n 
C 1 206 TYR 206 280 280 TYR TYR C . n 
C 1 207 GLN 207 281 281 GLN GLN C . n 
C 1 208 VAL 208 282 282 VAL VAL C . n 
C 1 209 LEU 209 283 283 LEU LEU C . n 
C 1 210 ASN 210 284 284 ASN ASN C . n 
C 1 211 GLU 211 285 285 GLU GLU C . n 
C 1 212 VAL 212 286 286 VAL VAL C . n 
C 1 213 VAL 213 287 287 VAL VAL C . n 
C 1 214 ILE 214 288 288 ILE ILE C . n 
C 1 215 ASP 215 289 289 ASP ASP C . n 
C 1 216 ARG 216 290 290 ARG ARG C . n 
C 1 217 GLY 217 291 291 GLY GLY C . n 
C 1 218 PRO 218 292 292 PRO PRO C . n 
C 1 219 SER 219 293 293 SER SER C . n 
C 1 220 SER 220 294 294 SER SER C . n 
C 1 221 TYR 221 295 295 TYR TYR C . n 
C 1 222 LEU 222 296 296 LEU LEU C . n 
C 1 223 SER 223 297 297 SER SER C . n 
C 1 224 ASN 224 298 298 ASN ASN C . n 
C 1 225 VAL 225 299 299 VAL VAL C . n 
C 1 226 ASP 226 300 300 ASP ASP C . n 
C 1 227 VAL 227 301 301 VAL VAL C . n 
C 1 228 TYR 228 302 302 TYR TYR C . n 
C 1 229 LEU 229 303 303 LEU LEU C . n 
C 1 230 ASP 230 304 304 ASP ASP C . n 
C 1 231 GLY 231 305 305 GLY GLY C . n 
C 1 232 HIS 232 306 306 HIS HIS C . n 
C 1 233 LEU 233 307 307 LEU LEU C . n 
C 1 234 ILE 234 308 308 ILE ILE C . n 
C 1 235 THR 235 309 309 THR THR C . n 
C 1 236 THR 236 310 310 THR THR C . n 
C 1 237 VAL 237 311 311 VAL VAL C . n 
C 1 238 GLN 238 312 312 GLN GLN C . n 
C 1 239 GLY 239 313 313 GLY GLY C . n 
C 1 240 ASP 240 314 314 ASP ASP C . n 
C 1 241 GLY 241 315 315 GLY GLY C . n 
C 1 242 VAL 242 316 316 VAL VAL C . n 
C 1 243 ILE 243 317 317 ILE ILE C . n 
C 1 244 VAL 244 318 318 VAL VAL C . n 
C 1 245 SER 245 319 319 SER SER C . n 
C 1 246 THR 246 320 320 THR THR C . n 
C 1 247 PRO 247 321 321 PRO PRO C . n 
C 1 248 THR 248 322 322 THR THR C . n 
C 1 249 GLY 249 323 323 GLY GLY C . n 
C 1 250 SER 250 324 324 SER SER C . n 
C 1 251 THR 251 325 325 THR THR C . n 
C 1 252 ALA 252 326 326 ALA ALA C . n 
C 1 253 TYR 253 327 327 TYR TYR C . n 
C 1 254 ALA 254 328 328 ALA ALA C . n 
C 1 255 ALA 255 329 329 ALA ALA C . n 
C 1 256 ALA 256 330 330 ALA ALA C . n 
C 1 257 ALA 257 331 331 ALA ALA C . n 
C 1 258 GLY 258 332 332 GLY GLY C . n 
C 1 259 ALA 259 333 333 ALA ALA C . n 
C 1 260 SER 260 334 334 SER SER C . n 
C 1 261 MET 261 335 335 MET MET C . n 
C 1 262 ILE 262 336 336 ILE ILE C . n 
C 1 263 HIS 263 337 337 HIS HIS C . n 
C 1 264 PRO 264 338 338 PRO PRO C . n 
C 1 265 ASN 265 339 339 ASN ASN C . n 
C 1 266 VAL 266 340 340 VAL VAL C . n 
C 1 267 PRO 267 341 341 PRO PRO C . n 
C 1 268 ALA 268 342 342 ALA ALA C . n 
C 1 269 ILE 269 343 343 ILE ILE C . n 
C 1 270 MET 270 344 344 MET MET C . n 
C 1 271 ILE 271 345 345 ILE ILE C . n 
C 1 272 THR 272 346 346 THR THR C . n 
C 1 273 PRO 273 347 347 PRO PRO C . n 
C 1 274 ILE 274 348 348 ILE ILE C . n 
C 1 275 CYS 275 349 349 CYS CYS C . n 
C 1 276 PRO 276 350 350 PRO PRO C . n 
C 1 277 HIS 277 351 351 HIS HIS C . n 
C 1 278 SER 278 352 352 SER SER C . n 
C 1 279 LEU 279 353 353 LEU LEU C . n 
C 1 280 SER 280 354 354 SER SER C . n 
C 1 281 PHE 281 355 355 PHE PHE C . n 
C 1 282 ARG 282 356 356 ARG ARG C . n 
C 1 283 PRO 283 357 357 PRO PRO C . n 
C 1 284 ILE 284 358 358 ILE ILE C . n 
C 1 285 VAL 285 359 359 VAL VAL C . n 
C 1 286 VAL 286 360 360 VAL VAL C . n 
C 1 287 PRO 287 361 361 PRO PRO C . n 
C 1 288 ALA 288 362 362 ALA ALA C . n 
C 1 289 GLY 289 363 363 GLY GLY C . n 
C 1 290 VAL 290 364 364 VAL VAL C . n 
C 1 291 GLU 291 365 365 GLU GLU C . n 
C 1 292 LEU 292 366 366 LEU LEU C . n 
C 1 293 LYS 293 367 367 LYS LYS C . n 
C 1 294 ILE 294 368 368 ILE ILE C . n 
C 1 295 MET 295 369 369 MET MET C . n 
C 1 296 LEU 296 370 370 LEU LEU C . n 
C 1 297 SER 297 371 371 SER SER C . n 
C 1 298 PRO 298 372 372 PRO PRO C . n 
C 1 299 GLU 299 373 373 GLU GLU C . n 
C 1 300 ALA 300 374 374 ALA ALA C . n 
C 1 301 ARG 301 375 375 ARG ARG C . n 
C 1 302 ASN 302 376 376 ASN ASN C . n 
C 1 303 THR 303 377 377 THR THR C . n 
C 1 304 ALA 304 378 378 ALA ALA C . n 
C 1 305 TRP 305 379 379 TRP TRP C . n 
C 1 306 VAL 306 380 380 VAL VAL C . n 
C 1 307 SER 307 381 381 SER SER C . n 
C 1 308 PHE 308 382 382 PHE PHE C . n 
C 1 309 ASP 309 383 383 ASP ASP C . n 
C 1 310 GLY 310 384 384 GLY GLY C . n 
C 1 311 ARG 311 385 385 ARG ARG C . n 
C 1 312 LYS 312 386 386 LYS LYS C . n 
C 1 313 ARG 313 387 387 ARG ARG C . n 
C 1 314 GLN 314 388 388 GLN GLN C . n 
C 1 315 GLU 315 389 389 GLU GLU C . n 
C 1 316 ILE 316 390 390 ILE ILE C . n 
C 1 317 ARG 317 391 391 ARG ARG C . n 
C 1 318 HIS 318 392 392 HIS HIS C . n 
C 1 319 GLY 319 393 393 GLY GLY C . n 
C 1 320 ASP 320 394 394 ASP ASP C . n 
C 1 321 SER 321 395 395 SER SER C . n 
C 1 322 ILE 322 396 396 ILE ILE C . n 
C 1 323 SER 323 397 397 SER SER C . n 
C 1 324 ILE 324 398 398 ILE ILE C . n 
C 1 325 THR 325 399 399 THR THR C . n 
C 1 326 THR 326 400 400 THR THR C . n 
C 1 327 SER 327 401 401 SER SER C . n 
C 1 328 THR 328 402 402 THR THR C . n 
C 1 329 TYR 329 403 403 TYR TYR C . n 
C 1 330 PRO 330 404 404 PRO PRO C . n 
C 1 331 LEU 331 405 405 LEU LEU C . n 
C 1 332 PRO 332 406 406 PRO PRO C . n 
C 1 333 SER 333 407 407 SER SER C . n 
C 1 334 ILE 334 408 408 ILE ILE C . n 
C 1 335 CYS 335 409 409 CYS CYS C . n 
C 1 336 VAL 336 410 410 VAL VAL C . n 
C 1 337 ARG 337 411 411 ARG ARG C . n 
C 1 338 ASP 338 412 412 ASP ASP C . n 
C 1 339 PRO 339 413 413 PRO PRO C . n 
C 1 340 VAL 340 414 414 VAL VAL C . n 
C 1 341 SER 341 415 415 SER SER C . n 
C 1 342 ASP 342 416 416 ASP ASP C . n 
C 1 343 TRP 343 417 417 TRP TRP C . n 
C 1 344 PHE 344 418 418 PHE PHE C . n 
C 1 345 GLU 345 419 419 GLU GLU C . n 
C 1 346 SER 346 420 420 SER SER C . n 
C 1 347 LEU 347 421 421 LEU LEU C . n 
C 1 348 ALA 348 422 422 ALA ALA C . n 
C 1 349 GLN 349 423 423 GLN GLN C . n 
C 1 350 CYS 350 424 424 CYS CYS C . n 
C 1 351 LEU 351 425 425 LEU LEU C . n 
C 1 352 HIS 352 426 426 HIS HIS C . n 
C 1 353 TRP 353 427 427 TRP TRP C . n 
C 1 354 ASN 354 428 428 ASN ASN C . n 
C 1 355 VAL 355 429 429 VAL VAL C . n 
C 1 356 ARG 356 430 ?   ?   ?   C . n 
C 1 357 LYS 357 431 ?   ?   ?   C . n 
C 1 358 LYS 358 432 ?   ?   ?   C . n 
C 1 359 GLN 359 433 ?   ?   ?   C . n 
C 1 360 ALA 360 434 ?   ?   ?   C . n 
C 1 361 HIS 361 435 ?   ?   ?   C . n 
C 1 362 PHE 362 436 ?   ?   ?   C . n 
C 1 363 GLU 363 437 ?   ?   ?   C . n 
C 1 364 LEU 364 438 ?   ?   ?   C . n 
C 1 365 GLY 365 439 ?   ?   ?   C . n 
C 1 366 LEU 366 440 ?   ?   ?   C . n 
C 1 367 GLU 367 441 ?   ?   ?   C . n 
C 1 368 HIS 368 442 ?   ?   ?   C . n 
C 1 369 HIS 369 443 ?   ?   ?   C . n 
C 1 370 HIS 370 444 ?   ?   ?   C . n 
C 1 371 HIS 371 445 ?   ?   ?   C . n 
C 1 372 HIS 372 446 ?   ?   ?   C . n 
C 1 373 HIS 373 447 ?   ?   ?   C . n 
D 1 1   MET 1   75  ?   ?   ?   D . n 
D 1 2   PRO 2   76  ?   ?   ?   D . n 
D 1 3   SER 3   77  ?   ?   ?   D . n 
D 1 4   PRO 4   78  ?   ?   ?   D . n 
D 1 5   VAL 5   79  ?   ?   ?   D . n 
D 1 6   THR 6   80  ?   ?   ?   D . n 
D 1 7   THR 7   81  ?   ?   ?   D . n 
D 1 8   PHE 8   82  ?   ?   ?   D . n 
D 1 9   GLY 9   83  ?   ?   ?   D . n 
D 1 10  PRO 10  84  ?   ?   ?   D . n 
D 1 11  LYS 11  85  ?   ?   ?   D . n 
D 1 12  ALA 12  86  ?   ?   ?   D . n 
D 1 13  THR 13  87  ?   ?   ?   D . n 
D 1 14  VAL 14  88  ?   ?   ?   D . n 
D 1 15  GLU 15  89  ?   ?   ?   D . n 
D 1 16  THR 16  90  ?   ?   ?   D . n 
D 1 17  GLN 17  91  ?   ?   ?   D . n 
D 1 18  ASP 18  92  ?   ?   ?   D . n 
D 1 19  PRO 19  93  ?   ?   ?   D . n 
D 1 20  ALA 20  94  ?   ?   ?   D . n 
D 1 21  SER 21  95  95  SER SER D . n 
D 1 22  VAL 22  96  96  VAL VAL D . n 
D 1 23  ARG 23  97  97  ARG ARG D . n 
D 1 24  LEU 24  98  98  LEU LEU D . n 
D 1 25  THR 25  99  99  THR THR D . n 
D 1 26  TRP 26  100 100 TRP TRP D . n 
D 1 27  ASN 27  101 101 ASN ASN D . n 
D 1 28  LYS 28  102 102 LYS LYS D . n 
D 1 29  SER 29  103 103 SER SER D . n 
D 1 30  PRO 30  104 104 PRO PRO D . n 
D 1 31  LYS 31  105 105 LYS LYS D . n 
D 1 32  SER 32  106 106 SER SER D . n 
D 1 33  VAL 33  107 107 VAL VAL D . n 
D 1 34  LEU 34  108 108 LEU LEU D . n 
D 1 35  VAL 35  109 109 VAL VAL D . n 
D 1 36  ILE 36  110 110 ILE ILE D . n 
D 1 37  LYS 37  111 111 LYS LYS D . n 
D 1 38  LYS 38  112 112 LYS LYS D . n 
D 1 39  MET 39  113 113 MET MET D . n 
D 1 40  ARG 40  114 114 ARG ARG D . n 
D 1 41  ASP 41  115 115 ASP ASP D . n 
D 1 42  ALA 42  116 116 ALA ALA D . n 
D 1 43  SER 43  117 117 SER SER D . n 
D 1 44  LEU 44  118 118 LEU LEU D . n 
D 1 45  LEU 45  119 119 LEU LEU D . n 
D 1 46  GLN 46  120 120 GLN GLN D . n 
D 1 47  PRO 47  121 121 PRO PRO D . n 
D 1 48  PHE 48  122 122 PHE PHE D . n 
D 1 49  LYS 49  123 123 LYS LYS D . n 
D 1 50  GLU 50  124 124 GLU GLU D . n 
D 1 51  LEU 51  125 125 LEU LEU D . n 
D 1 52  CYS 52  126 126 CYS CYS D . n 
D 1 53  THR 53  127 127 THR THR D . n 
D 1 54  HIS 54  128 128 HIS HIS D . n 
D 1 55  LEU 55  129 129 LEU LEU D . n 
D 1 56  MET 56  130 130 MET MET D . n 
D 1 57  GLU 57  131 131 GLU GLU D . n 
D 1 58  GLU 58  132 132 GLU GLU D . n 
D 1 59  ASN 59  133 133 ASN ASN D . n 
D 1 60  MET 60  134 134 MET MET D . n 
D 1 61  ILE 61  135 135 ILE ILE D . n 
D 1 62  VAL 62  136 136 VAL VAL D . n 
D 1 63  TYR 63  137 137 TYR TYR D . n 
D 1 64  VAL 64  138 138 VAL VAL D . n 
D 1 65  GLU 65  139 139 GLU GLU D . n 
D 1 66  LYS 66  140 140 LYS LYS D . n 
D 1 67  LYS 67  141 141 LYS LYS D . n 
D 1 68  VAL 68  142 142 VAL VAL D . n 
D 1 69  LEU 69  143 143 LEU LEU D . n 
D 1 70  GLU 70  144 144 GLU GLU D . n 
D 1 71  ASP 71  145 145 ASP ASP D . n 
D 1 72  PRO 72  146 146 PRO PRO D . n 
D 1 73  ALA 73  147 147 ALA ALA D . n 
D 1 74  ILE 74  148 148 ILE ILE D . n 
D 1 75  ALA 75  149 149 ALA ALA D . n 
D 1 76  SER 76  150 150 SER SER D . n 
D 1 77  ASP 77  151 151 ASP ASP D . n 
D 1 78  GLU 78  152 152 GLU GLU D . n 
D 1 79  SER 79  153 153 SER SER D . n 
D 1 80  PHE 80  154 154 PHE PHE D . n 
D 1 81  GLY 81  155 155 GLY GLY D . n 
D 1 82  ALA 82  156 156 ALA ALA D . n 
D 1 83  VAL 83  157 157 VAL VAL D . n 
D 1 84  LYS 84  158 158 LYS LYS D . n 
D 1 85  LYS 85  159 159 LYS LYS D . n 
D 1 86  LYS 86  160 160 LYS LYS D . n 
D 1 87  PHE 87  161 161 PHE PHE D . n 
D 1 88  THR 88  162 162 THR THR D . n 
D 1 89  THR 89  163 ?   ?   ?   D . n 
D 1 90  PHE 90  164 ?   ?   ?   D . n 
D 1 91  ARG 91  165 ?   ?   ?   D . n 
D 1 92  GLU 92  166 ?   ?   ?   D . n 
D 1 93  ASP 93  167 ?   ?   ?   D . n 
D 1 94  TYR 94  168 ?   ?   ?   D . n 
D 1 95  ASP 95  169 ?   ?   ?   D . n 
D 1 96  ASP 96  170 ?   ?   ?   D . n 
D 1 97  ILE 97  171 ?   ?   ?   D . n 
D 1 98  SER 98  172 ?   ?   ?   D . n 
D 1 99  ASN 99  173 173 ASN ASN D . n 
D 1 100 GLN 100 174 174 GLN GLN D . n 
D 1 101 ILE 101 175 175 ILE ILE D . n 
D 1 102 ASP 102 176 176 ASP ASP D . n 
D 1 103 PHE 103 177 177 PHE PHE D . n 
D 1 104 ILE 104 178 178 ILE ILE D . n 
D 1 105 ILE 105 179 179 ILE ILE D . n 
D 1 106 CYS 106 180 180 CYS CYS D . n 
D 1 107 LEU 107 181 181 LEU LEU D . n 
D 1 108 GLY 108 182 182 GLY GLY D . n 
D 1 109 GLY 109 183 183 GLY GLY D . n 
D 1 110 ASP 110 184 184 ASP ASP D . n 
D 1 111 GLY 111 185 185 GLY GLY D . n 
D 1 112 THR 112 186 186 THR THR D . n 
D 1 113 LEU 113 187 187 LEU LEU D . n 
D 1 114 LEU 114 188 188 LEU LEU D . n 
D 1 115 TYR 115 189 189 TYR TYR D . n 
D 1 116 ALA 116 190 190 ALA ALA D . n 
D 1 117 SER 117 191 191 SER SER D . n 
D 1 118 SER 118 192 192 SER SER D . n 
D 1 119 LEU 119 193 193 LEU LEU D . n 
D 1 120 PHE 120 194 194 PHE PHE D . n 
D 1 121 GLN 121 195 195 GLN GLN D . n 
D 1 122 GLY 122 196 196 GLY GLY D . n 
D 1 123 SER 123 197 197 SER SER D . n 
D 1 124 VAL 124 198 198 VAL VAL D . n 
D 1 125 PRO 125 199 199 PRO PRO D . n 
D 1 126 PRO 126 200 200 PRO PRO D . n 
D 1 127 VAL 127 201 201 VAL VAL D . n 
D 1 128 MET 128 202 202 MET MET D . n 
D 1 129 ALA 129 203 203 ALA ALA D . n 
D 1 130 PHE 130 204 204 PHE PHE D . n 
D 1 131 HIS 131 205 205 HIS HIS D . n 
D 1 132 LEU 132 206 206 LEU LEU D . n 
D 1 133 GLY 133 207 207 GLY GLY D . n 
D 1 134 SER 134 208 208 SER SER D . n 
D 1 135 LEU 135 209 209 LEU LEU D . n 
D 1 136 GLY 136 210 210 GLY GLY D . n 
D 1 137 PHE 137 211 211 PHE PHE D . n 
D 1 138 LEU 138 212 212 LEU LEU D . n 
D 1 139 THR 139 213 213 THR THR D . n 
D 1 140 PRO 140 214 214 PRO PRO D . n 
D 1 141 PHE 141 215 215 PHE PHE D . n 
D 1 142 SER 142 216 216 SER SER D . n 
D 1 143 PHE 143 217 217 PHE PHE D . n 
D 1 144 GLU 144 218 218 GLU GLU D . n 
D 1 145 ASN 145 219 219 ASN ASN D . n 
D 1 146 PHE 146 220 220 PHE PHE D . n 
D 1 147 GLN 147 221 221 GLN GLN D . n 
D 1 148 SER 148 222 222 SER SER D . n 
D 1 149 GLN 149 223 223 GLN GLN D . n 
D 1 150 VAL 150 224 224 VAL VAL D . n 
D 1 151 THR 151 225 225 THR THR D . n 
D 1 152 GLN 152 226 226 GLN GLN D . n 
D 1 153 VAL 153 227 227 VAL VAL D . n 
D 1 154 ILE 154 228 228 ILE ILE D . n 
D 1 155 GLU 155 229 229 GLU GLU D . n 
D 1 156 GLY 156 230 230 GLY GLY D . n 
D 1 157 ASN 157 231 231 ASN ASN D . n 
D 1 158 ALA 158 232 232 ALA ALA D . n 
D 1 159 ALA 159 233 233 ALA ALA D . n 
D 1 160 VAL 160 234 234 VAL VAL D . n 
D 1 161 VAL 161 235 235 VAL VAL D . n 
D 1 162 LEU 162 236 236 LEU LEU D . n 
D 1 163 ARG 163 237 237 ARG ARG D . n 
D 1 164 SER 164 238 238 SER SER D . n 
D 1 165 ARG 165 239 239 ARG ARG D . n 
D 1 166 LEU 166 240 240 LEU LEU D . n 
D 1 167 LYS 167 241 241 LYS LYS D . n 
D 1 168 VAL 168 242 242 VAL VAL D . n 
D 1 169 ARG 169 243 243 ARG ARG D . n 
D 1 170 VAL 170 244 244 VAL VAL D . n 
D 1 171 VAL 171 245 245 VAL VAL D . n 
D 1 172 LYS 172 246 246 LYS LYS D . n 
D 1 173 GLU 173 247 247 GLU GLU D . n 
D 1 174 LEU 174 248 ?   ?   ?   D . n 
D 1 175 ARG 175 249 ?   ?   ?   D . n 
D 1 176 GLY 176 250 ?   ?   ?   D . n 
D 1 177 LYS 177 251 ?   ?   ?   D . n 
D 1 178 LYS 178 252 ?   ?   ?   D . n 
D 1 179 THR 179 253 ?   ?   ?   D . n 
D 1 180 ALA 180 254 ?   ?   ?   D . n 
D 1 181 VAL 181 255 ?   ?   ?   D . n 
D 1 182 HIS 182 256 ?   ?   ?   D . n 
D 1 183 ASN 183 257 ?   ?   ?   D . n 
D 1 184 GLY 184 258 ?   ?   ?   D . n 
D 1 185 LEU 185 259 ?   ?   ?   D . n 
D 1 186 GLY 186 260 ?   ?   ?   D . n 
D 1 187 GLU 187 261 ?   ?   ?   D . n 
D 1 188 ASN 188 262 ?   ?   ?   D . n 
D 1 189 GLY 189 263 ?   ?   ?   D . n 
D 1 190 SER 190 264 ?   ?   ?   D . n 
D 1 191 GLN 191 265 ?   ?   ?   D . n 
D 1 192 ALA 192 266 ?   ?   ?   D . n 
D 1 193 ALA 193 267 ?   ?   ?   D . n 
D 1 194 GLY 194 268 ?   ?   ?   D . n 
D 1 195 LEU 195 269 ?   ?   ?   D . n 
D 1 196 ASP 196 270 ?   ?   ?   D . n 
D 1 197 MET 197 271 ?   ?   ?   D . n 
D 1 198 ASP 198 272 ?   ?   ?   D . n 
D 1 199 VAL 199 273 ?   ?   ?   D . n 
D 1 200 GLY 200 274 ?   ?   ?   D . n 
D 1 201 LYS 201 275 ?   ?   ?   D . n 
D 1 202 GLN 202 276 ?   ?   ?   D . n 
D 1 203 ALA 203 277 277 ALA ALA D . n 
D 1 204 MET 204 278 278 MET MET D . n 
D 1 205 GLN 205 279 279 GLN GLN D . n 
D 1 206 TYR 206 280 280 TYR TYR D . n 
D 1 207 GLN 207 281 281 GLN GLN D . n 
D 1 208 VAL 208 282 282 VAL VAL D . n 
D 1 209 LEU 209 283 283 LEU LEU D . n 
D 1 210 ASN 210 284 284 ASN ASN D . n 
D 1 211 GLU 211 285 285 GLU GLU D . n 
D 1 212 VAL 212 286 286 VAL VAL D . n 
D 1 213 VAL 213 287 287 VAL VAL D . n 
D 1 214 ILE 214 288 288 ILE ILE D . n 
D 1 215 ASP 215 289 289 ASP ASP D . n 
D 1 216 ARG 216 290 290 ARG ARG D . n 
D 1 217 GLY 217 291 291 GLY GLY D . n 
D 1 218 PRO 218 292 292 PRO PRO D . n 
D 1 219 SER 219 293 293 SER SER D . n 
D 1 220 SER 220 294 294 SER SER D . n 
D 1 221 TYR 221 295 295 TYR TYR D . n 
D 1 222 LEU 222 296 296 LEU LEU D . n 
D 1 223 SER 223 297 297 SER SER D . n 
D 1 224 ASN 224 298 298 ASN ASN D . n 
D 1 225 VAL 225 299 299 VAL VAL D . n 
D 1 226 ASP 226 300 300 ASP ASP D . n 
D 1 227 VAL 227 301 301 VAL VAL D . n 
D 1 228 TYR 228 302 302 TYR TYR D . n 
D 1 229 LEU 229 303 303 LEU LEU D . n 
D 1 230 ASP 230 304 304 ASP ASP D . n 
D 1 231 GLY 231 305 305 GLY GLY D . n 
D 1 232 HIS 232 306 306 HIS HIS D . n 
D 1 233 LEU 233 307 307 LEU LEU D . n 
D 1 234 ILE 234 308 308 ILE ILE D . n 
D 1 235 THR 235 309 309 THR THR D . n 
D 1 236 THR 236 310 310 THR THR D . n 
D 1 237 VAL 237 311 311 VAL VAL D . n 
D 1 238 GLN 238 312 312 GLN GLN D . n 
D 1 239 GLY 239 313 313 GLY GLY D . n 
D 1 240 ASP 240 314 314 ASP ASP D . n 
D 1 241 GLY 241 315 315 GLY GLY D . n 
D 1 242 VAL 242 316 316 VAL VAL D . n 
D 1 243 ILE 243 317 317 ILE ILE D . n 
D 1 244 VAL 244 318 318 VAL VAL D . n 
D 1 245 SER 245 319 319 SER SER D . n 
D 1 246 THR 246 320 320 THR THR D . n 
D 1 247 PRO 247 321 321 PRO PRO D . n 
D 1 248 THR 248 322 322 THR THR D . n 
D 1 249 GLY 249 323 323 GLY GLY D . n 
D 1 250 SER 250 324 324 SER SER D . n 
D 1 251 THR 251 325 325 THR THR D . n 
D 1 252 ALA 252 326 326 ALA ALA D . n 
D 1 253 TYR 253 327 327 TYR TYR D . n 
D 1 254 ALA 254 328 328 ALA ALA D . n 
D 1 255 ALA 255 329 329 ALA ALA D . n 
D 1 256 ALA 256 330 330 ALA ALA D . n 
D 1 257 ALA 257 331 331 ALA ALA D . n 
D 1 258 GLY 258 332 332 GLY GLY D . n 
D 1 259 ALA 259 333 333 ALA ALA D . n 
D 1 260 SER 260 334 334 SER SER D . n 
D 1 261 MET 261 335 335 MET MET D . n 
D 1 262 ILE 262 336 336 ILE ILE D . n 
D 1 263 HIS 263 337 337 HIS HIS D . n 
D 1 264 PRO 264 338 338 PRO PRO D . n 
D 1 265 ASN 265 339 339 ASN ASN D . n 
D 1 266 VAL 266 340 340 VAL VAL D . n 
D 1 267 PRO 267 341 341 PRO PRO D . n 
D 1 268 ALA 268 342 342 ALA ALA D . n 
D 1 269 ILE 269 343 343 ILE ILE D . n 
D 1 270 MET 270 344 344 MET MET D . n 
D 1 271 ILE 271 345 345 ILE ILE D . n 
D 1 272 THR 272 346 346 THR THR D . n 
D 1 273 PRO 273 347 347 PRO PRO D . n 
D 1 274 ILE 274 348 348 ILE ILE D . n 
D 1 275 CYS 275 349 349 CYS CYS D . n 
D 1 276 PRO 276 350 350 PRO PRO D . n 
D 1 277 HIS 277 351 351 HIS HIS D . n 
D 1 278 SER 278 352 352 SER SER D . n 
D 1 279 LEU 279 353 353 LEU LEU D . n 
D 1 280 SER 280 354 354 SER SER D . n 
D 1 281 PHE 281 355 355 PHE PHE D . n 
D 1 282 ARG 282 356 356 ARG ARG D . n 
D 1 283 PRO 283 357 357 PRO PRO D . n 
D 1 284 ILE 284 358 358 ILE ILE D . n 
D 1 285 VAL 285 359 359 VAL VAL D . n 
D 1 286 VAL 286 360 360 VAL VAL D . n 
D 1 287 PRO 287 361 361 PRO PRO D . n 
D 1 288 ALA 288 362 362 ALA ALA D . n 
D 1 289 GLY 289 363 363 GLY GLY D . n 
D 1 290 VAL 290 364 364 VAL VAL D . n 
D 1 291 GLU 291 365 365 GLU GLU D . n 
D 1 292 LEU 292 366 366 LEU LEU D . n 
D 1 293 LYS 293 367 367 LYS LYS D . n 
D 1 294 ILE 294 368 368 ILE ILE D . n 
D 1 295 MET 295 369 369 MET MET D . n 
D 1 296 LEU 296 370 370 LEU LEU D . n 
D 1 297 SER 297 371 371 SER SER D . n 
D 1 298 PRO 298 372 372 PRO PRO D . n 
D 1 299 GLU 299 373 373 GLU GLU D . n 
D 1 300 ALA 300 374 374 ALA ALA D . n 
D 1 301 ARG 301 375 375 ARG ARG D . n 
D 1 302 ASN 302 376 376 ASN ASN D . n 
D 1 303 THR 303 377 377 THR THR D . n 
D 1 304 ALA 304 378 378 ALA ALA D . n 
D 1 305 TRP 305 379 379 TRP TRP D . n 
D 1 306 VAL 306 380 380 VAL VAL D . n 
D 1 307 SER 307 381 381 SER SER D . n 
D 1 308 PHE 308 382 382 PHE PHE D . n 
D 1 309 ASP 309 383 383 ASP ASP D . n 
D 1 310 GLY 310 384 384 GLY GLY D . n 
D 1 311 ARG 311 385 385 ARG ARG D . n 
D 1 312 LYS 312 386 386 LYS LYS D . n 
D 1 313 ARG 313 387 387 ARG ARG D . n 
D 1 314 GLN 314 388 388 GLN GLN D . n 
D 1 315 GLU 315 389 389 GLU GLU D . n 
D 1 316 ILE 316 390 390 ILE ILE D . n 
D 1 317 ARG 317 391 391 ARG ARG D . n 
D 1 318 HIS 318 392 392 HIS HIS D . n 
D 1 319 GLY 319 393 393 GLY GLY D . n 
D 1 320 ASP 320 394 394 ASP ASP D . n 
D 1 321 SER 321 395 395 SER SER D . n 
D 1 322 ILE 322 396 396 ILE ILE D . n 
D 1 323 SER 323 397 397 SER SER D . n 
D 1 324 ILE 324 398 398 ILE ILE D . n 
D 1 325 THR 325 399 399 THR THR D . n 
D 1 326 THR 326 400 400 THR THR D . n 
D 1 327 SER 327 401 401 SER SER D . n 
D 1 328 THR 328 402 402 THR THR D . n 
D 1 329 TYR 329 403 403 TYR TYR D . n 
D 1 330 PRO 330 404 404 PRO PRO D . n 
D 1 331 LEU 331 405 405 LEU LEU D . n 
D 1 332 PRO 332 406 406 PRO PRO D . n 
D 1 333 SER 333 407 407 SER SER D . n 
D 1 334 ILE 334 408 408 ILE ILE D . n 
D 1 335 CYS 335 409 409 CYS CYS D . n 
D 1 336 VAL 336 410 410 VAL VAL D . n 
D 1 337 ARG 337 411 411 ARG ARG D . n 
D 1 338 ASP 338 412 412 ASP ASP D . n 
D 1 339 PRO 339 413 413 PRO PRO D . n 
D 1 340 VAL 340 414 414 VAL VAL D . n 
D 1 341 SER 341 415 415 SER SER D . n 
D 1 342 ASP 342 416 416 ASP ASP D . n 
D 1 343 TRP 343 417 417 TRP TRP D . n 
D 1 344 PHE 344 418 418 PHE PHE D . n 
D 1 345 GLU 345 419 419 GLU GLU D . n 
D 1 346 SER 346 420 420 SER SER D . n 
D 1 347 LEU 347 421 421 LEU LEU D . n 
D 1 348 ALA 348 422 422 ALA ALA D . n 
D 1 349 GLN 349 423 423 GLN GLN D . n 
D 1 350 CYS 350 424 424 CYS CYS D . n 
D 1 351 LEU 351 425 425 LEU LEU D . n 
D 1 352 HIS 352 426 426 HIS HIS D . n 
D 1 353 TRP 353 427 427 TRP TRP D . n 
D 1 354 ASN 354 428 428 ASN ASN D . n 
D 1 355 VAL 355 429 ?   ?   ?   D . n 
D 1 356 ARG 356 430 ?   ?   ?   D . n 
D 1 357 LYS 357 431 ?   ?   ?   D . n 
D 1 358 LYS 358 432 ?   ?   ?   D . n 
D 1 359 GLN 359 433 ?   ?   ?   D . n 
D 1 360 ALA 360 434 ?   ?   ?   D . n 
D 1 361 HIS 361 435 ?   ?   ?   D . n 
D 1 362 PHE 362 436 ?   ?   ?   D . n 
D 1 363 GLU 363 437 ?   ?   ?   D . n 
D 1 364 LEU 364 438 ?   ?   ?   D . n 
D 1 365 GLY 365 439 ?   ?   ?   D . n 
D 1 366 LEU 366 440 ?   ?   ?   D . n 
D 1 367 GLU 367 441 ?   ?   ?   D . n 
D 1 368 HIS 368 442 ?   ?   ?   D . n 
D 1 369 HIS 369 443 ?   ?   ?   D . n 
D 1 370 HIS 370 444 ?   ?   ?   D . n 
D 1 371 HIS 371 445 ?   ?   ?   D . n 
D 1 372 HIS 372 446 ?   ?   ?   D . n 
D 1 373 HIS 373 447 ?   ?   ?   D . n 
# 
_pdbx_unobs_or_zero_occ_atoms.id               1 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id     SER 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id      172 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id     OG 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id     ? 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id    A 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id    SER 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id     98 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id    OG 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CR4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CR4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CR4 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9CR4 
_struct.title                        'CryoEM Structure of the C-terminally truncated form of human NAD Kinase' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CR4 
_struct_keywords.text            'catalyzes the reaction of ATP + NAD+ = ADP + H+ + NADP+, SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    NADK_HUMAN 
_struct_ref.pdbx_db_accession          O95544 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QDPASQRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESFGAVKKKFCTFREDYDD
ISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRG
KKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAA
AGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICV
RDPVSDWFESLAQCLHWNVRKKQAHFE
;
_struct_ref.pdbx_align_begin           91 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CR4 A 17 ? 363 ? O95544 91 ? 437 ? 91 437 
2 1 9CR4 B 17 ? 363 ? O95544 91 ? 437 ? 91 437 
3 1 9CR4 C 17 ? 363 ? O95544 91 ? 437 ? 91 437 
4 1 9CR4 D 17 ? 363 ? O95544 91 ? 437 ? 91 437 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CR4 MET A 1   ? UNP O95544 ?   ?   'initiating methionine' 75  1   
1 9CR4 PRO A 2   ? UNP O95544 ?   ?   'expression tag'        76  2   
1 9CR4 SER A 3   ? UNP O95544 ?   ?   'expression tag'        77  3   
1 9CR4 PRO A 4   ? UNP O95544 ?   ?   'expression tag'        78  4   
1 9CR4 VAL A 5   ? UNP O95544 ?   ?   'expression tag'        79  5   
1 9CR4 THR A 6   ? UNP O95544 ?   ?   'expression tag'        80  6   
1 9CR4 THR A 7   ? UNP O95544 ?   ?   'expression tag'        81  7   
1 9CR4 PHE A 8   ? UNP O95544 ?   ?   'expression tag'        82  8   
1 9CR4 GLY A 9   ? UNP O95544 ?   ?   'expression tag'        83  9   
1 9CR4 PRO A 10  ? UNP O95544 ?   ?   'expression tag'        84  10  
1 9CR4 LYS A 11  ? UNP O95544 ?   ?   'expression tag'        85  11  
1 9CR4 ALA A 12  ? UNP O95544 ?   ?   'expression tag'        86  12  
1 9CR4 THR A 13  ? UNP O95544 ?   ?   'expression tag'        87  13  
1 9CR4 VAL A 14  ? UNP O95544 ?   ?   'expression tag'        88  14  
1 9CR4 GLU A 15  ? UNP O95544 ?   ?   'expression tag'        89  15  
1 9CR4 THR A 16  ? UNP O95544 ?   ?   'expression tag'        90  16  
1 9CR4 VAL A 22  ? UNP O95544 GLN 96  conflict                96  17  
1 9CR4 THR A 88  ? UNP O95544 CYS 162 conflict                162 18  
1 9CR4 THR A 328 ? UNP O95544 CYS 402 conflict                402 19  
1 9CR4 LEU A 364 ? UNP O95544 ?   ?   'expression tag'        438 20  
1 9CR4 GLY A 365 ? UNP O95544 ?   ?   'expression tag'        439 21  
1 9CR4 LEU A 366 ? UNP O95544 ?   ?   'expression tag'        440 22  
1 9CR4 GLU A 367 ? UNP O95544 ?   ?   'expression tag'        441 23  
1 9CR4 HIS A 368 ? UNP O95544 ?   ?   'expression tag'        442 24  
1 9CR4 HIS A 369 ? UNP O95544 ?   ?   'expression tag'        443 25  
1 9CR4 HIS A 370 ? UNP O95544 ?   ?   'expression tag'        444 26  
1 9CR4 HIS A 371 ? UNP O95544 ?   ?   'expression tag'        445 27  
1 9CR4 HIS A 372 ? UNP O95544 ?   ?   'expression tag'        446 28  
1 9CR4 HIS A 373 ? UNP O95544 ?   ?   'expression tag'        447 29  
2 9CR4 MET B 1   ? UNP O95544 ?   ?   'initiating methionine' 75  30  
2 9CR4 PRO B 2   ? UNP O95544 ?   ?   'expression tag'        76  31  
2 9CR4 SER B 3   ? UNP O95544 ?   ?   'expression tag'        77  32  
2 9CR4 PRO B 4   ? UNP O95544 ?   ?   'expression tag'        78  33  
2 9CR4 VAL B 5   ? UNP O95544 ?   ?   'expression tag'        79  34  
2 9CR4 THR B 6   ? UNP O95544 ?   ?   'expression tag'        80  35  
2 9CR4 THR B 7   ? UNP O95544 ?   ?   'expression tag'        81  36  
2 9CR4 PHE B 8   ? UNP O95544 ?   ?   'expression tag'        82  37  
2 9CR4 GLY B 9   ? UNP O95544 ?   ?   'expression tag'        83  38  
2 9CR4 PRO B 10  ? UNP O95544 ?   ?   'expression tag'        84  39  
2 9CR4 LYS B 11  ? UNP O95544 ?   ?   'expression tag'        85  40  
2 9CR4 ALA B 12  ? UNP O95544 ?   ?   'expression tag'        86  41  
2 9CR4 THR B 13  ? UNP O95544 ?   ?   'expression tag'        87  42  
2 9CR4 VAL B 14  ? UNP O95544 ?   ?   'expression tag'        88  43  
2 9CR4 GLU B 15  ? UNP O95544 ?   ?   'expression tag'        89  44  
2 9CR4 THR B 16  ? UNP O95544 ?   ?   'expression tag'        90  45  
2 9CR4 VAL B 22  ? UNP O95544 GLN 96  conflict                96  46  
2 9CR4 THR B 88  ? UNP O95544 CYS 162 conflict                162 47  
2 9CR4 THR B 328 ? UNP O95544 CYS 402 conflict                402 48  
2 9CR4 LEU B 364 ? UNP O95544 ?   ?   'expression tag'        438 49  
2 9CR4 GLY B 365 ? UNP O95544 ?   ?   'expression tag'        439 50  
2 9CR4 LEU B 366 ? UNP O95544 ?   ?   'expression tag'        440 51  
2 9CR4 GLU B 367 ? UNP O95544 ?   ?   'expression tag'        441 52  
2 9CR4 HIS B 368 ? UNP O95544 ?   ?   'expression tag'        442 53  
2 9CR4 HIS B 369 ? UNP O95544 ?   ?   'expression tag'        443 54  
2 9CR4 HIS B 370 ? UNP O95544 ?   ?   'expression tag'        444 55  
2 9CR4 HIS B 371 ? UNP O95544 ?   ?   'expression tag'        445 56  
2 9CR4 HIS B 372 ? UNP O95544 ?   ?   'expression tag'        446 57  
2 9CR4 HIS B 373 ? UNP O95544 ?   ?   'expression tag'        447 58  
3 9CR4 MET C 1   ? UNP O95544 ?   ?   'initiating methionine' 75  59  
3 9CR4 PRO C 2   ? UNP O95544 ?   ?   'expression tag'        76  60  
3 9CR4 SER C 3   ? UNP O95544 ?   ?   'expression tag'        77  61  
3 9CR4 PRO C 4   ? UNP O95544 ?   ?   'expression tag'        78  62  
3 9CR4 VAL C 5   ? UNP O95544 ?   ?   'expression tag'        79  63  
3 9CR4 THR C 6   ? UNP O95544 ?   ?   'expression tag'        80  64  
3 9CR4 THR C 7   ? UNP O95544 ?   ?   'expression tag'        81  65  
3 9CR4 PHE C 8   ? UNP O95544 ?   ?   'expression tag'        82  66  
3 9CR4 GLY C 9   ? UNP O95544 ?   ?   'expression tag'        83  67  
3 9CR4 PRO C 10  ? UNP O95544 ?   ?   'expression tag'        84  68  
3 9CR4 LYS C 11  ? UNP O95544 ?   ?   'expression tag'        85  69  
3 9CR4 ALA C 12  ? UNP O95544 ?   ?   'expression tag'        86  70  
3 9CR4 THR C 13  ? UNP O95544 ?   ?   'expression tag'        87  71  
3 9CR4 VAL C 14  ? UNP O95544 ?   ?   'expression tag'        88  72  
3 9CR4 GLU C 15  ? UNP O95544 ?   ?   'expression tag'        89  73  
3 9CR4 THR C 16  ? UNP O95544 ?   ?   'expression tag'        90  74  
3 9CR4 VAL C 22  ? UNP O95544 GLN 96  conflict                96  75  
3 9CR4 THR C 88  ? UNP O95544 CYS 162 conflict                162 76  
3 9CR4 THR C 328 ? UNP O95544 CYS 402 conflict                402 77  
3 9CR4 LEU C 364 ? UNP O95544 ?   ?   'expression tag'        438 78  
3 9CR4 GLY C 365 ? UNP O95544 ?   ?   'expression tag'        439 79  
3 9CR4 LEU C 366 ? UNP O95544 ?   ?   'expression tag'        440 80  
3 9CR4 GLU C 367 ? UNP O95544 ?   ?   'expression tag'        441 81  
3 9CR4 HIS C 368 ? UNP O95544 ?   ?   'expression tag'        442 82  
3 9CR4 HIS C 369 ? UNP O95544 ?   ?   'expression tag'        443 83  
3 9CR4 HIS C 370 ? UNP O95544 ?   ?   'expression tag'        444 84  
3 9CR4 HIS C 371 ? UNP O95544 ?   ?   'expression tag'        445 85  
3 9CR4 HIS C 372 ? UNP O95544 ?   ?   'expression tag'        446 86  
3 9CR4 HIS C 373 ? UNP O95544 ?   ?   'expression tag'        447 87  
4 9CR4 MET D 1   ? UNP O95544 ?   ?   'initiating methionine' 75  88  
4 9CR4 PRO D 2   ? UNP O95544 ?   ?   'expression tag'        76  89  
4 9CR4 SER D 3   ? UNP O95544 ?   ?   'expression tag'        77  90  
4 9CR4 PRO D 4   ? UNP O95544 ?   ?   'expression tag'        78  91  
4 9CR4 VAL D 5   ? UNP O95544 ?   ?   'expression tag'        79  92  
4 9CR4 THR D 6   ? UNP O95544 ?   ?   'expression tag'        80  93  
4 9CR4 THR D 7   ? UNP O95544 ?   ?   'expression tag'        81  94  
4 9CR4 PHE D 8   ? UNP O95544 ?   ?   'expression tag'        82  95  
4 9CR4 GLY D 9   ? UNP O95544 ?   ?   'expression tag'        83  96  
4 9CR4 PRO D 10  ? UNP O95544 ?   ?   'expression tag'        84  97  
4 9CR4 LYS D 11  ? UNP O95544 ?   ?   'expression tag'        85  98  
4 9CR4 ALA D 12  ? UNP O95544 ?   ?   'expression tag'        86  99  
4 9CR4 THR D 13  ? UNP O95544 ?   ?   'expression tag'        87  100 
4 9CR4 VAL D 14  ? UNP O95544 ?   ?   'expression tag'        88  101 
4 9CR4 GLU D 15  ? UNP O95544 ?   ?   'expression tag'        89  102 
4 9CR4 THR D 16  ? UNP O95544 ?   ?   'expression tag'        90  103 
4 9CR4 VAL D 22  ? UNP O95544 GLN 96  conflict                96  104 
4 9CR4 THR D 88  ? UNP O95544 CYS 162 conflict                162 105 
4 9CR4 THR D 328 ? UNP O95544 CYS 402 conflict                402 106 
4 9CR4 LEU D 364 ? UNP O95544 ?   ?   'expression tag'        438 107 
4 9CR4 GLY D 365 ? UNP O95544 ?   ?   'expression tag'        439 108 
4 9CR4 LEU D 366 ? UNP O95544 ?   ?   'expression tag'        440 109 
4 9CR4 GLU D 367 ? UNP O95544 ?   ?   'expression tag'        441 110 
4 9CR4 HIS D 368 ? UNP O95544 ?   ?   'expression tag'        442 111 
4 9CR4 HIS D 369 ? UNP O95544 ?   ?   'expression tag'        443 112 
4 9CR4 HIS D 370 ? UNP O95544 ?   ?   'expression tag'        444 113 
4 9CR4 HIS D 371 ? UNP O95544 ?   ?   'expression tag'        445 114 
4 9CR4 HIS D 372 ? UNP O95544 ?   ?   'expression tag'        446 115 
4 9CR4 HIS D 373 ? UNP O95544 ?   ?   'expression tag'        447 116 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 41  ? SER A 43  ? ASP A 115 SER A 117 5 ? 3  
HELX_P HELX_P2  AA2 LEU A 44  ? GLU A 58  ? LEU A 118 GLU A 132 1 ? 15 
HELX_P HELX_P3  AA3 LYS A 67  ? GLU A 70  ? LYS A 141 GLU A 144 5 ? 4  
HELX_P HELX_P4  AA4 ASP A 71  ? ASP A 77  ? ASP A 145 ASP A 151 1 ? 7  
HELX_P HELX_P5  AA5 PHE A 80  ? LYS A 85  ? PHE A 154 LYS A 159 1 ? 6  
HELX_P HELX_P6  AA6 THR A 112 ? PHE A 120 ? THR A 186 PHE A 194 1 ? 9  
HELX_P HELX_P7  AA7 ASN A 145 ? GLY A 156 ? ASN A 219 GLY A 230 1 ? 12 
HELX_P HELX_P8  AA8 THR A 246 ? ALA A 252 ? THR A 320 ALA A 326 5 ? 7  
HELX_P HELX_P9  AA9 ALA A 254 ? GLY A 258 ? ALA A 328 GLY A 332 5 ? 5  
HELX_P HELX_P10 AB1 ASP A 338 ? LEU A 351 ? ASP A 412 LEU A 425 1 ? 14 
HELX_P HELX_P11 AB2 ASP B 41  ? SER B 43  ? ASP B 115 SER B 117 5 ? 3  
HELX_P HELX_P12 AB3 LEU B 44  ? GLU B 58  ? LEU B 118 GLU B 132 1 ? 15 
HELX_P HELX_P13 AB4 LYS B 67  ? GLU B 70  ? LYS B 141 GLU B 144 5 ? 4  
HELX_P HELX_P14 AB5 ASP B 71  ? ASP B 77  ? ASP B 145 ASP B 151 1 ? 7  
HELX_P HELX_P15 AB6 PHE B 80  ? LYS B 85  ? PHE B 154 LYS B 159 1 ? 6  
HELX_P HELX_P16 AB7 THR B 112 ? PHE B 120 ? THR B 186 PHE B 194 1 ? 9  
HELX_P HELX_P17 AB8 ASN B 145 ? GLY B 156 ? ASN B 219 GLY B 230 1 ? 12 
HELX_P HELX_P18 AB9 PRO B 247 ? THR B 251 ? PRO B 321 THR B 325 5 ? 5  
HELX_P HELX_P19 AC1 ALA B 252 ? ALA B 257 ? ALA B 326 ALA B 331 1 ? 6  
HELX_P HELX_P20 AC2 ASP B 338 ? LEU B 351 ? ASP B 412 LEU B 425 1 ? 14 
HELX_P HELX_P21 AC3 ASP C 41  ? SER C 43  ? ASP C 115 SER C 117 5 ? 3  
HELX_P HELX_P22 AC4 LEU C 44  ? GLU C 58  ? LEU C 118 GLU C 132 1 ? 15 
HELX_P HELX_P23 AC5 LYS C 67  ? GLU C 70  ? LYS C 141 GLU C 144 5 ? 4  
HELX_P HELX_P24 AC6 ASP C 71  ? ASP C 77  ? ASP C 145 ASP C 151 1 ? 7  
HELX_P HELX_P25 AC7 PHE C 80  ? LYS C 85  ? PHE C 154 LYS C 159 1 ? 6  
HELX_P HELX_P26 AC8 GLY C 111 ? PHE C 120 ? GLY C 185 PHE C 194 1 ? 10 
HELX_P HELX_P27 AC9 ASN C 145 ? GLY C 156 ? ASN C 219 GLY C 230 1 ? 12 
HELX_P HELX_P28 AD1 THR C 246 ? ALA C 252 ? THR C 320 ALA C 326 5 ? 7  
HELX_P HELX_P29 AD2 ALA C 254 ? GLY C 258 ? ALA C 328 GLY C 332 5 ? 5  
HELX_P HELX_P30 AD3 VAL C 340 ? CYS C 350 ? VAL C 414 CYS C 424 1 ? 11 
HELX_P HELX_P31 AD4 ASP D 41  ? SER D 43  ? ASP D 115 SER D 117 5 ? 3  
HELX_P HELX_P32 AD5 LEU D 44  ? GLU D 58  ? LEU D 118 GLU D 132 1 ? 15 
HELX_P HELX_P33 AD6 LYS D 67  ? GLU D 70  ? LYS D 141 GLU D 144 5 ? 4  
HELX_P HELX_P34 AD7 ASP D 71  ? ASP D 77  ? ASP D 145 ASP D 151 1 ? 7  
HELX_P HELX_P35 AD8 PHE D 80  ? LYS D 85  ? PHE D 154 LYS D 159 1 ? 6  
HELX_P HELX_P36 AD9 GLY D 111 ? PHE D 120 ? GLY D 185 PHE D 194 1 ? 10 
HELX_P HELX_P37 AE1 ASN D 145 ? GLY D 156 ? ASN D 219 GLY D 230 1 ? 12 
HELX_P HELX_P38 AE2 THR D 246 ? THR D 251 ? THR D 320 THR D 325 5 ? 6  
HELX_P HELX_P39 AE3 ALA D 252 ? ALA D 257 ? ALA D 326 ALA D 331 1 ? 6  
HELX_P HELX_P40 AE4 VAL D 340 ? CYS D 350 ? VAL D 414 CYS D 424 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 7 ? 
AA4 ? 9 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
AA7 ? 4 ? 
AA8 ? 2 ? 
AA9 ? 7 ? 
AB1 ? 9 ? 
AB2 ? 5 ? 
AB3 ? 2 ? 
AB4 ? 6 ? 
AB5 ? 5 ? 
AB6 ? 3 ? 
AB7 ? 3 ? 
AB8 ? 5 ? 
AB9 ? 2 ? 
AC1 ? 6 ? 
AC2 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA4 7 8 ? anti-parallel 
AA4 8 9 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? parallel      
AA7 3 4 ? parallel      
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 6 7 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB1 6 7 ? anti-parallel 
AB1 7 8 ? anti-parallel 
AB1 8 9 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? parallel      
AB2 3 4 ? parallel      
AB2 4 5 ? parallel      
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? parallel      
AB8 1 2 ? parallel      
AB8 2 3 ? parallel      
AB8 3 4 ? parallel      
AB8 4 5 ? parallel      
AB9 1 2 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC1 4 5 ? anti-parallel 
AC1 5 6 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 61  ? VAL A 64  ? ILE A 135 VAL A 138 
AA1 2 SER A 32  ? LYS A 37  ? SER A 106 LYS A 111 
AA1 3 PHE A 103 ? LEU A 107 ? PHE A 177 LEU A 181 
AA1 4 VAL A 127 ? HIS A 131 ? VAL A 201 HIS A 205 
AA1 5 PHE A 141 ? SER A 142 ? PHE A 215 SER A 216 
AA2 1 VAL A 160 ? ARG A 163 ? VAL A 234 ARG A 237 
AA2 2 LEU A 331 ? ILE A 334 ? LEU A 405 ILE A 408 
AA3 1 GLN A 205 ? VAL A 208 ? GLN A 279 VAL A 282 
AA3 2 LEU A 166 ? VAL A 171 ? LEU A 240 VAL A 245 
AA3 3 SER A 321 ? THR A 326 ? SER A 395 THR A 400 
AA3 4 LEU A 292 ? LEU A 296 ? LEU A 366 LEU A 370 
AA3 5 SER A 223 ? LEU A 229 ? SER A 297 LEU A 303 
AA3 6 THR A 235 ? VAL A 242 ? THR A 309 VAL A 316 
AA3 7 PRO A 273 ? PRO A 276 ? PRO A 347 PRO A 350 
AA4 1 GLN A 205 ? VAL A 208 ? GLN A 279 VAL A 282 
AA4 2 LEU A 166 ? VAL A 171 ? LEU A 240 VAL A 245 
AA4 3 SER A 321 ? THR A 326 ? SER A 395 THR A 400 
AA4 4 LEU A 292 ? LEU A 296 ? LEU A 366 LEU A 370 
AA4 5 SER A 223 ? LEU A 229 ? SER A 297 LEU A 303 
AA4 6 THR A 235 ? VAL A 242 ? THR A 309 VAL A 316 
AA4 7 VAL A 212 ? ASP A 215 ? VAL A 286 ASP A 289 
AA4 8 ALA A 304 ? PHE A 308 ? ALA A 378 PHE A 382 
AA4 9 GLN A 314 ? ILE A 316 ? GLN A 388 ILE A 390 
AA5 1 MET A 261 ? ILE A 262 ? MET A 335 ILE A 336 
AA5 2 ILE B 284 ? PRO B 287 ? ILE B 358 PRO B 361 
AA5 3 ALA B 268 ? ILE B 271 ? ALA B 342 ILE B 345 
AA6 1 ALA A 268 ? MET A 270 ? ALA A 342 MET A 344 
AA6 2 VAL A 285 ? PRO A 287 ? VAL A 359 PRO A 361 
AA7 1 ILE B 61  ? VAL B 64  ? ILE B 135 VAL B 138 
AA7 2 SER B 32  ? LYS B 37  ? SER B 106 LYS B 111 
AA7 3 PHE B 103 ? LEU B 107 ? PHE B 177 LEU B 181 
AA7 4 VAL B 127 ? PHE B 130 ? VAL B 201 PHE B 204 
AA8 1 VAL B 160 ? ARG B 163 ? VAL B 234 ARG B 237 
AA8 2 LEU B 331 ? ILE B 334 ? LEU B 405 ILE B 408 
AA9 1 MET B 204 ? VAL B 208 ? MET B 278 VAL B 282 
AA9 2 LEU B 166 ? VAL B 171 ? LEU B 240 VAL B 245 
AA9 3 SER B 321 ? THR B 326 ? SER B 395 THR B 400 
AA9 4 LEU B 292 ? LEU B 296 ? LEU B 366 LEU B 370 
AA9 5 SER B 223 ? LEU B 229 ? SER B 297 LEU B 303 
AA9 6 HIS B 232 ? VAL B 242 ? HIS B 306 VAL B 316 
AA9 7 PRO B 273 ? PRO B 276 ? PRO B 347 PRO B 350 
AB1 1 MET B 204 ? VAL B 208 ? MET B 278 VAL B 282 
AB1 2 LEU B 166 ? VAL B 171 ? LEU B 240 VAL B 245 
AB1 3 SER B 321 ? THR B 326 ? SER B 395 THR B 400 
AB1 4 LEU B 292 ? LEU B 296 ? LEU B 366 LEU B 370 
AB1 5 SER B 223 ? LEU B 229 ? SER B 297 LEU B 303 
AB1 6 HIS B 232 ? VAL B 242 ? HIS B 306 VAL B 316 
AB1 7 VAL B 212 ? ASP B 215 ? VAL B 286 ASP B 289 
AB1 8 ALA B 304 ? PHE B 308 ? ALA B 378 PHE B 382 
AB1 9 GLN B 314 ? ILE B 316 ? GLN B 388 ILE B 390 
AB2 1 ILE C 61  ? VAL C 64  ? ILE C 135 VAL C 138 
AB2 2 SER C 32  ? ILE C 36  ? SER C 106 ILE C 110 
AB2 3 PHE C 103 ? LEU C 107 ? PHE C 177 LEU C 181 
AB2 4 VAL C 127 ? HIS C 131 ? VAL C 201 HIS C 205 
AB2 5 PHE C 141 ? SER C 142 ? PHE C 215 SER C 216 
AB3 1 ALA C 159 ? ARG C 163 ? ALA C 233 ARG C 237 
AB3 2 LEU C 331 ? CYS C 335 ? LEU C 405 CYS C 409 
AB4 1 MET C 204 ? VAL C 208 ? MET C 278 VAL C 282 
AB4 2 LEU C 166 ? VAL C 171 ? LEU C 240 VAL C 245 
AB4 3 SER C 321 ? THR C 326 ? SER C 395 THR C 400 
AB4 4 LEU C 292 ? LEU C 296 ? LEU C 366 LEU C 370 
AB4 5 SER C 223 ? LEU C 229 ? SER C 297 LEU C 303 
AB4 6 THR C 235 ? GLY C 239 ? THR C 309 GLY C 313 
AB5 1 PRO C 273 ? ILE C 274 ? PRO C 347 ILE C 348 
AB5 2 GLY C 241 ? VAL C 242 ? GLY C 315 VAL C 316 
AB5 3 VAL C 212 ? ASP C 215 ? VAL C 286 ASP C 289 
AB5 4 ALA C 304 ? PHE C 308 ? ALA C 378 PHE C 382 
AB5 5 GLN C 314 ? ILE C 316 ? GLN C 388 ILE C 390 
AB6 1 MET C 261 ? ILE C 262 ? MET C 335 ILE C 336 
AB6 2 ILE D 284 ? PRO D 287 ? ILE D 358 PRO D 361 
AB6 3 ALA D 268 ? ILE D 271 ? ALA D 342 ILE D 345 
AB7 1 ALA C 268 ? ILE C 271 ? ALA C 342 ILE C 345 
AB7 2 ILE C 284 ? PRO C 287 ? ILE C 358 PRO C 361 
AB7 3 MET D 261 ? ILE D 262 ? MET D 335 ILE D 336 
AB8 1 ILE D 61  ? VAL D 64  ? ILE D 135 VAL D 138 
AB8 2 SER D 32  ? ILE D 36  ? SER D 106 ILE D 110 
AB8 3 PHE D 103 ? LEU D 107 ? PHE D 177 LEU D 181 
AB8 4 VAL D 127 ? HIS D 131 ? VAL D 201 HIS D 205 
AB8 5 PHE D 141 ? SER D 142 ? PHE D 215 SER D 216 
AB9 1 VAL D 160 ? ARG D 163 ? VAL D 234 ARG D 237 
AB9 2 LEU D 331 ? ILE D 334 ? LEU D 405 ILE D 408 
AC1 1 MET D 204 ? VAL D 208 ? MET D 278 VAL D 282 
AC1 2 LEU D 166 ? VAL D 171 ? LEU D 240 VAL D 245 
AC1 3 SER D 321 ? THR D 325 ? SER D 395 THR D 399 
AC1 4 GLU D 291 ? LEU D 296 ? GLU D 365 LEU D 370 
AC1 5 SER D 223 ? LEU D 229 ? SER D 297 LEU D 303 
AC1 6 HIS D 232 ? GLY D 239 ? HIS D 306 GLY D 313 
AC2 1 PRO D 273 ? ILE D 274 ? PRO D 347 ILE D 348 
AC2 2 GLY D 241 ? VAL D 242 ? GLY D 315 VAL D 316 
AC2 3 VAL D 212 ? ASP D 215 ? VAL D 286 ASP D 289 
AC2 4 ALA D 304 ? PHE D 308 ? ALA D 378 PHE D 382 
AC2 5 GLN D 314 ? ILE D 316 ? GLN D 388 ILE D 390 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O TYR A 63  ? O TYR A 137 N VAL A 33  ? N VAL A 107 
AA1 2 3 N ILE A 36  ? N ILE A 110 O LEU A 107 ? O LEU A 181 
AA1 3 4 N CYS A 106 ? N CYS A 180 O MET A 128 ? O MET A 202 
AA1 4 5 N HIS A 131 ? N HIS A 205 O PHE A 141 ? O PHE A 215 
AA2 1 2 N ARG A 163 ? N ARG A 237 O LEU A 331 ? O LEU A 405 
AA3 1 2 O VAL A 208 ? O VAL A 282 N LEU A 166 ? N LEU A 240 
AA3 2 3 N LYS A 167 ? N LYS A 241 O THR A 325 ? O THR A 399 
AA3 3 4 O ILE A 322 ? O ILE A 396 N ILE A 294 ? N ILE A 368 
AA3 4 5 O LYS A 293 ? O LYS A 367 N TYR A 228 ? N TYR A 302 
AA3 5 6 N SER A 223 ? N SER A 297 O GLY A 239 ? O GLY A 313 
AA3 6 7 N GLY A 241 ? N GLY A 315 O ILE A 274 ? O ILE A 348 
AA4 1 2 O VAL A 208 ? O VAL A 282 N LEU A 166 ? N LEU A 240 
AA4 2 3 N LYS A 167 ? N LYS A 241 O THR A 325 ? O THR A 399 
AA4 3 4 O ILE A 322 ? O ILE A 396 N ILE A 294 ? N ILE A 368 
AA4 4 5 O LYS A 293 ? O LYS A 367 N TYR A 228 ? N TYR A 302 
AA4 5 6 N SER A 223 ? N SER A 297 O GLY A 239 ? O GLY A 313 
AA4 6 7 O VAL A 242 ? O VAL A 316 N ILE A 214 ? N ILE A 288 
AA4 7 8 N VAL A 213 ? N VAL A 287 O SER A 307 ? O SER A 381 
AA4 8 9 N ALA A 304 ? N ALA A 378 O ILE A 316 ? O ILE A 390 
AA5 1 2 N MET A 261 ? N MET A 335 O VAL B 285 ? O VAL B 359 
AA5 2 3 O ILE B 284 ? O ILE B 358 N ILE B 271 ? N ILE B 345 
AA6 1 2 N ILE A 269 ? N ILE A 343 O VAL A 286 ? O VAL A 360 
AA7 1 2 O TYR B 63  ? O TYR B 137 N VAL B 33  ? N VAL B 107 
AA7 2 3 N LEU B 34  ? N LEU B 108 O PHE B 103 ? O PHE B 177 
AA7 3 4 N CYS B 106 ? N CYS B 180 O MET B 128 ? O MET B 202 
AA8 1 2 N ARG B 163 ? N ARG B 237 O LEU B 331 ? O LEU B 405 
AA9 1 2 O TYR B 206 ? O TYR B 280 N VAL B 168 ? N VAL B 242 
AA9 2 3 N VAL B 171 ? N VAL B 245 O SER B 321 ? O SER B 395 
AA9 3 4 O ILE B 324 ? O ILE B 398 N LEU B 292 ? N LEU B 366 
AA9 4 5 O MET B 295 ? O MET B 369 N ASP B 226 ? N ASP B 300 
AA9 5 6 N LEU B 229 ? N LEU B 303 O HIS B 232 ? O HIS B 306 
AA9 6 7 N GLY B 241 ? N GLY B 315 O ILE B 274 ? O ILE B 348 
AB1 1 2 O TYR B 206 ? O TYR B 280 N VAL B 168 ? N VAL B 242 
AB1 2 3 N VAL B 171 ? N VAL B 245 O SER B 321 ? O SER B 395 
AB1 3 4 O ILE B 324 ? O ILE B 398 N LEU B 292 ? N LEU B 366 
AB1 4 5 O MET B 295 ? O MET B 369 N ASP B 226 ? N ASP B 300 
AB1 5 6 N LEU B 229 ? N LEU B 303 O HIS B 232 ? O HIS B 306 
AB1 6 7 O VAL B 242 ? O VAL B 316 N ILE B 214 ? N ILE B 288 
AB1 7 8 N VAL B 213 ? N VAL B 287 O SER B 307 ? O SER B 381 
AB1 8 9 N ALA B 304 ? N ALA B 378 O ILE B 316 ? O ILE B 390 
AB2 1 2 O TYR C 63  ? O TYR C 137 N VAL C 33  ? N VAL C 107 
AB2 2 3 N LEU C 34  ? N LEU C 108 O PHE C 103 ? O PHE C 177 
AB2 3 4 N CYS C 106 ? N CYS C 180 O PHE C 130 ? O PHE C 204 
AB2 4 5 N HIS C 131 ? N HIS C 205 O PHE C 141 ? O PHE C 215 
AB3 1 2 N ARG C 163 ? N ARG C 237 O LEU C 331 ? O LEU C 405 
AB4 1 2 O TYR C 206 ? O TYR C 280 N VAL C 168 ? N VAL C 242 
AB4 2 3 N LYS C 167 ? N LYS C 241 O THR C 325 ? O THR C 399 
AB4 3 4 O ILE C 324 ? O ILE C 398 N LEU C 292 ? N LEU C 366 
AB4 4 5 O LYS C 293 ? O LYS C 367 N TYR C 228 ? N TYR C 302 
AB4 5 6 N VAL C 227 ? N VAL C 301 O THR C 235 ? O THR C 309 
AB5 1 2 O ILE C 274 ? O ILE C 348 N GLY C 241 ? N GLY C 315 
AB5 2 3 O VAL C 242 ? O VAL C 316 N ILE C 214 ? N ILE C 288 
AB5 3 4 N ASP C 215 ? N ASP C 289 O TRP C 305 ? O TRP C 379 
AB5 4 5 N ALA C 304 ? N ALA C 378 O ILE C 316 ? O ILE C 390 
AB6 1 2 N MET C 261 ? N MET C 335 O VAL D 285 ? O VAL D 359 
AB6 2 3 O VAL D 286 ? O VAL D 360 N ILE D 269 ? N ILE D 343 
AB7 1 2 N ILE C 269 ? N ILE C 343 O VAL C 286 ? O VAL C 360 
AB7 2 3 N VAL C 285 ? N VAL C 359 O MET D 261 ? O MET D 335 
AB8 1 2 O TYR D 63  ? O TYR D 137 N VAL D 33  ? N VAL D 107 
AB8 2 3 N ILE D 36  ? N ILE D 110 O LEU D 107 ? O LEU D 181 
AB8 3 4 N CYS D 106 ? N CYS D 180 O MET D 128 ? O MET D 202 
AB8 4 5 N HIS D 131 ? N HIS D 205 O PHE D 141 ? O PHE D 215 
AB9 1 2 N ARG D 163 ? N ARG D 237 O LEU D 331 ? O LEU D 405 
AC1 1 2 O VAL D 208 ? O VAL D 282 N LEU D 166 ? N LEU D 240 
AC1 2 3 N LYS D 167 ? N LYS D 241 O THR D 325 ? O THR D 399 
AC1 3 4 O ILE D 324 ? O ILE D 398 N LEU D 292 ? N LEU D 366 
AC1 4 5 O LYS D 293 ? O LYS D 367 N TYR D 228 ? N TYR D 302 
AC1 5 6 N LEU D 229 ? N LEU D 303 O HIS D 232 ? O HIS D 306 
AC2 1 2 O ILE D 274 ? O ILE D 348 N GLY D 241 ? N GLY D 315 
AC2 2 3 O VAL D 242 ? O VAL D 316 N ILE D 214 ? N ILE D 288 
AC2 3 4 N VAL D 213 ? N VAL D 287 O SER D 307 ? O SER D 381 
AC2 4 5 N ALA D 304 ? N ALA D 378 O ILE D 316 ? O ILE D 390 
# 
_pdbx_entry_details.entry_id                   9CR4 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OD1 
_pdbx_validate_close_contact.auth_asym_id_1   D 
_pdbx_validate_close_contact.auth_comp_id_1   ASP 
_pdbx_validate_close_contact.auth_seq_id_1    412 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OG 
_pdbx_validate_close_contact.auth_asym_id_2   D 
_pdbx_validate_close_contact.auth_comp_id_2   SER 
_pdbx_validate_close_contact.auth_seq_id_2    415 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 98  ? ? 177.83  161.68  
2  1 ASN A 101 ? ? 62.99   -68.02  
3  1 MET A 113 ? ? 63.12   172.64  
4  1 PHE A 161 ? ? -79.95  -169.60 
5  1 ASN A 284 ? ? -94.07  -62.55  
6  1 LEU A 307 ? ? -35.39  122.76  
7  1 ASN A 376 ? ? 64.49   166.84  
8  1 ARG A 385 ? ? -125.30 -167.28 
9  1 LYS A 386 ? ? -37.68  124.78  
10 1 ARG A 391 ? ? -118.53 -169.73 
11 1 ASN B 101 ? ? 62.88   -69.58  
12 1 MET B 113 ? ? 64.09   174.62  
13 1 ASP B 184 ? ? 67.38   -3.29   
14 1 ASN B 284 ? ? -93.51  -61.69  
15 1 SER B 293 ? ? -160.42 -168.10 
16 1 PRO B 338 ? ? -68.49  0.87    
17 1 ARG B 385 ? ? -79.95  -165.35 
18 1 ASN C 101 ? ? 62.58   -70.09  
19 1 MET C 113 ? ? 65.91   164.21  
20 1 LEU C 143 ? ? -83.56  49.61   
21 1 ASN C 284 ? ? -93.39  -61.31  
22 1 LEU C 307 ? ? -35.99  128.11  
23 1 PRO C 338 ? ? -69.90  3.89    
24 1 ASN C 376 ? ? 59.65   -173.01 
25 1 ARG C 385 ? ? -117.51 -168.68 
26 1 LYS C 386 ? ? -38.10  128.44  
27 1 ARG C 391 ? ? -102.95 -169.57 
28 1 VAL C 414 ? ? -92.03  -63.40  
29 1 ARG D 97  ? ? -94.05  -64.06  
30 1 ASN D 101 ? ? 63.29   -71.26  
31 1 MET D 113 ? ? 66.74   164.98  
32 1 LEU D 143 ? ? -82.09  47.83   
33 1 GLU D 144 ? ? -148.34 10.35   
34 1 ASN D 284 ? ? -92.06  -61.04  
35 1 PRO D 292 ? ? -68.46  65.06   
36 1 SER D 293 ? ? -164.96 -169.93 
37 1 TYR D 295 ? ? 69.29   160.92  
38 1 PRO D 338 ? ? -69.63  1.22    
39 1 ARG D 385 ? ? -125.19 -166.26 
40 1 LYS D 386 ? ? -38.05  127.45  
41 1 ARG D 391 ? ? -102.57 -169.39 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9CR4 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9CR4 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.81 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               316309 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '50 mM Tris (pH 7.8), 50 mM NaCl, and 2 mM DTT.' 
_em_buffer.pH            7.8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'human NAD Kinase' 
_em_entity_assembly.details              'Tetramer of c-terminally truncated form of human NAD Kinase' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9CR4 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9CR4 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   278 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9CR4 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9CR4 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        D2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 75  ? A MET 1   
2   1 Y 1 A PRO 76  ? A PRO 2   
3   1 Y 1 A SER 77  ? A SER 3   
4   1 Y 1 A PRO 78  ? A PRO 4   
5   1 Y 1 A VAL 79  ? A VAL 5   
6   1 Y 1 A THR 80  ? A THR 6   
7   1 Y 1 A THR 81  ? A THR 7   
8   1 Y 1 A PHE 82  ? A PHE 8   
9   1 Y 1 A GLY 83  ? A GLY 9   
10  1 Y 1 A PRO 84  ? A PRO 10  
11  1 Y 1 A LYS 85  ? A LYS 11  
12  1 Y 1 A ALA 86  ? A ALA 12  
13  1 Y 1 A THR 87  ? A THR 13  
14  1 Y 1 A VAL 88  ? A VAL 14  
15  1 Y 1 A GLU 89  ? A GLU 15  
16  1 Y 1 A THR 90  ? A THR 16  
17  1 Y 1 A GLN 91  ? A GLN 17  
18  1 Y 1 A ASP 92  ? A ASP 18  
19  1 Y 1 A PRO 93  ? A PRO 19  
20  1 Y 1 A ALA 94  ? A ALA 20  
21  1 Y 1 A THR 163 ? A THR 89  
22  1 Y 1 A PHE 164 ? A PHE 90  
23  1 Y 1 A ARG 165 ? A ARG 91  
24  1 Y 1 A GLU 166 ? A GLU 92  
25  1 Y 1 A ASP 167 ? A ASP 93  
26  1 Y 1 A TYR 168 ? A TYR 94  
27  1 Y 1 A ASP 169 ? A ASP 95  
28  1 Y 1 A ASP 170 ? A ASP 96  
29  1 Y 1 A ILE 171 ? A ILE 97  
30  1 Y 1 A LEU 248 ? A LEU 174 
31  1 Y 1 A ARG 249 ? A ARG 175 
32  1 Y 1 A GLY 250 ? A GLY 176 
33  1 Y 1 A LYS 251 ? A LYS 177 
34  1 Y 1 A LYS 252 ? A LYS 178 
35  1 Y 1 A THR 253 ? A THR 179 
36  1 Y 1 A ALA 254 ? A ALA 180 
37  1 Y 1 A VAL 255 ? A VAL 181 
38  1 Y 1 A HIS 256 ? A HIS 182 
39  1 Y 1 A ASN 257 ? A ASN 183 
40  1 Y 1 A GLY 258 ? A GLY 184 
41  1 Y 1 A LEU 259 ? A LEU 185 
42  1 Y 1 A GLY 260 ? A GLY 186 
43  1 Y 1 A GLU 261 ? A GLU 187 
44  1 Y 1 A ASN 262 ? A ASN 188 
45  1 Y 1 A GLY 263 ? A GLY 189 
46  1 Y 1 A SER 264 ? A SER 190 
47  1 Y 1 A GLN 265 ? A GLN 191 
48  1 Y 1 A ALA 266 ? A ALA 192 
49  1 Y 1 A ALA 267 ? A ALA 193 
50  1 Y 1 A GLY 268 ? A GLY 194 
51  1 Y 1 A LEU 269 ? A LEU 195 
52  1 Y 1 A ASP 270 ? A ASP 196 
53  1 Y 1 A MET 271 ? A MET 197 
54  1 Y 1 A ASP 272 ? A ASP 198 
55  1 Y 1 A VAL 273 ? A VAL 199 
56  1 Y 1 A GLY 274 ? A GLY 200 
57  1 Y 1 A LYS 275 ? A LYS 201 
58  1 Y 1 A GLN 276 ? A GLN 202 
59  1 Y 1 A ARG 430 ? A ARG 356 
60  1 Y 1 A LYS 431 ? A LYS 357 
61  1 Y 1 A LYS 432 ? A LYS 358 
62  1 Y 1 A GLN 433 ? A GLN 359 
63  1 Y 1 A ALA 434 ? A ALA 360 
64  1 Y 1 A HIS 435 ? A HIS 361 
65  1 Y 1 A PHE 436 ? A PHE 362 
66  1 Y 1 A GLU 437 ? A GLU 363 
67  1 Y 1 A LEU 438 ? A LEU 364 
68  1 Y 1 A GLY 439 ? A GLY 365 
69  1 Y 1 A LEU 440 ? A LEU 366 
70  1 Y 1 A GLU 441 ? A GLU 367 
71  1 Y 1 A HIS 442 ? A HIS 368 
72  1 Y 1 A HIS 443 ? A HIS 369 
73  1 Y 1 A HIS 444 ? A HIS 370 
74  1 Y 1 A HIS 445 ? A HIS 371 
75  1 Y 1 A HIS 446 ? A HIS 372 
76  1 Y 1 A HIS 447 ? A HIS 373 
77  1 Y 1 B MET 75  ? B MET 1   
78  1 Y 1 B PRO 76  ? B PRO 2   
79  1 Y 1 B SER 77  ? B SER 3   
80  1 Y 1 B PRO 78  ? B PRO 4   
81  1 Y 1 B VAL 79  ? B VAL 5   
82  1 Y 1 B THR 80  ? B THR 6   
83  1 Y 1 B THR 81  ? B THR 7   
84  1 Y 1 B PHE 82  ? B PHE 8   
85  1 Y 1 B GLY 83  ? B GLY 9   
86  1 Y 1 B PRO 84  ? B PRO 10  
87  1 Y 1 B LYS 85  ? B LYS 11  
88  1 Y 1 B ALA 86  ? B ALA 12  
89  1 Y 1 B THR 87  ? B THR 13  
90  1 Y 1 B VAL 88  ? B VAL 14  
91  1 Y 1 B GLU 89  ? B GLU 15  
92  1 Y 1 B THR 90  ? B THR 16  
93  1 Y 1 B GLN 91  ? B GLN 17  
94  1 Y 1 B ASP 92  ? B ASP 18  
95  1 Y 1 B PRO 93  ? B PRO 19  
96  1 Y 1 B ALA 94  ? B ALA 20  
97  1 Y 1 B THR 163 ? B THR 89  
98  1 Y 1 B PHE 164 ? B PHE 90  
99  1 Y 1 B ARG 165 ? B ARG 91  
100 1 Y 1 B GLU 166 ? B GLU 92  
101 1 Y 1 B ASP 167 ? B ASP 93  
102 1 Y 1 B TYR 168 ? B TYR 94  
103 1 Y 1 B ASP 169 ? B ASP 95  
104 1 Y 1 B ASP 170 ? B ASP 96  
105 1 Y 1 B ILE 171 ? B ILE 97  
106 1 Y 1 B SER 172 ? B SER 98  
107 1 Y 1 B ASN 173 ? B ASN 99  
108 1 Y 1 B GLU 247 ? B GLU 173 
109 1 Y 1 B LEU 248 ? B LEU 174 
110 1 Y 1 B ARG 249 ? B ARG 175 
111 1 Y 1 B GLY 250 ? B GLY 176 
112 1 Y 1 B LYS 251 ? B LYS 177 
113 1 Y 1 B LYS 252 ? B LYS 178 
114 1 Y 1 B THR 253 ? B THR 179 
115 1 Y 1 B ALA 254 ? B ALA 180 
116 1 Y 1 B VAL 255 ? B VAL 181 
117 1 Y 1 B HIS 256 ? B HIS 182 
118 1 Y 1 B ASN 257 ? B ASN 183 
119 1 Y 1 B GLY 258 ? B GLY 184 
120 1 Y 1 B LEU 259 ? B LEU 185 
121 1 Y 1 B GLY 260 ? B GLY 186 
122 1 Y 1 B GLU 261 ? B GLU 187 
123 1 Y 1 B ASN 262 ? B ASN 188 
124 1 Y 1 B GLY 263 ? B GLY 189 
125 1 Y 1 B SER 264 ? B SER 190 
126 1 Y 1 B GLN 265 ? B GLN 191 
127 1 Y 1 B ALA 266 ? B ALA 192 
128 1 Y 1 B ALA 267 ? B ALA 193 
129 1 Y 1 B GLY 268 ? B GLY 194 
130 1 Y 1 B LEU 269 ? B LEU 195 
131 1 Y 1 B ASP 270 ? B ASP 196 
132 1 Y 1 B MET 271 ? B MET 197 
133 1 Y 1 B ASP 272 ? B ASP 198 
134 1 Y 1 B VAL 273 ? B VAL 199 
135 1 Y 1 B GLY 274 ? B GLY 200 
136 1 Y 1 B LYS 275 ? B LYS 201 
137 1 Y 1 B GLN 276 ? B GLN 202 
138 1 Y 1 B TYR 295 ? B TYR 221 
139 1 Y 1 B ARG 430 ? B ARG 356 
140 1 Y 1 B LYS 431 ? B LYS 357 
141 1 Y 1 B LYS 432 ? B LYS 358 
142 1 Y 1 B GLN 433 ? B GLN 359 
143 1 Y 1 B ALA 434 ? B ALA 360 
144 1 Y 1 B HIS 435 ? B HIS 361 
145 1 Y 1 B PHE 436 ? B PHE 362 
146 1 Y 1 B GLU 437 ? B GLU 363 
147 1 Y 1 B LEU 438 ? B LEU 364 
148 1 Y 1 B GLY 439 ? B GLY 365 
149 1 Y 1 B LEU 440 ? B LEU 366 
150 1 Y 1 B GLU 441 ? B GLU 367 
151 1 Y 1 B HIS 442 ? B HIS 368 
152 1 Y 1 B HIS 443 ? B HIS 369 
153 1 Y 1 B HIS 444 ? B HIS 370 
154 1 Y 1 B HIS 445 ? B HIS 371 
155 1 Y 1 B HIS 446 ? B HIS 372 
156 1 Y 1 B HIS 447 ? B HIS 373 
157 1 Y 1 C MET 75  ? C MET 1   
158 1 Y 1 C PRO 76  ? C PRO 2   
159 1 Y 1 C SER 77  ? C SER 3   
160 1 Y 1 C PRO 78  ? C PRO 4   
161 1 Y 1 C VAL 79  ? C VAL 5   
162 1 Y 1 C THR 80  ? C THR 6   
163 1 Y 1 C THR 81  ? C THR 7   
164 1 Y 1 C PHE 82  ? C PHE 8   
165 1 Y 1 C GLY 83  ? C GLY 9   
166 1 Y 1 C PRO 84  ? C PRO 10  
167 1 Y 1 C LYS 85  ? C LYS 11  
168 1 Y 1 C ALA 86  ? C ALA 12  
169 1 Y 1 C THR 87  ? C THR 13  
170 1 Y 1 C VAL 88  ? C VAL 14  
171 1 Y 1 C GLU 89  ? C GLU 15  
172 1 Y 1 C THR 90  ? C THR 16  
173 1 Y 1 C GLN 91  ? C GLN 17  
174 1 Y 1 C ASP 92  ? C ASP 18  
175 1 Y 1 C PRO 93  ? C PRO 19  
176 1 Y 1 C ALA 94  ? C ALA 20  
177 1 Y 1 C SER 95  ? C SER 21  
178 1 Y 1 C THR 163 ? C THR 89  
179 1 Y 1 C PHE 164 ? C PHE 90  
180 1 Y 1 C ARG 165 ? C ARG 91  
181 1 Y 1 C GLU 166 ? C GLU 92  
182 1 Y 1 C ASP 167 ? C ASP 93  
183 1 Y 1 C TYR 168 ? C TYR 94  
184 1 Y 1 C ASP 169 ? C ASP 95  
185 1 Y 1 C ASP 170 ? C ASP 96  
186 1 Y 1 C ILE 171 ? C ILE 97  
187 1 Y 1 C SER 172 ? C SER 98  
188 1 Y 1 C ASN 173 ? C ASN 99  
189 1 Y 1 C LEU 248 ? C LEU 174 
190 1 Y 1 C ARG 249 ? C ARG 175 
191 1 Y 1 C GLY 250 ? C GLY 176 
192 1 Y 1 C LYS 251 ? C LYS 177 
193 1 Y 1 C LYS 252 ? C LYS 178 
194 1 Y 1 C THR 253 ? C THR 179 
195 1 Y 1 C ALA 254 ? C ALA 180 
196 1 Y 1 C VAL 255 ? C VAL 181 
197 1 Y 1 C HIS 256 ? C HIS 182 
198 1 Y 1 C ASN 257 ? C ASN 183 
199 1 Y 1 C GLY 258 ? C GLY 184 
200 1 Y 1 C LEU 259 ? C LEU 185 
201 1 Y 1 C GLY 260 ? C GLY 186 
202 1 Y 1 C GLU 261 ? C GLU 187 
203 1 Y 1 C ASN 262 ? C ASN 188 
204 1 Y 1 C GLY 263 ? C GLY 189 
205 1 Y 1 C SER 264 ? C SER 190 
206 1 Y 1 C GLN 265 ? C GLN 191 
207 1 Y 1 C ALA 266 ? C ALA 192 
208 1 Y 1 C ALA 267 ? C ALA 193 
209 1 Y 1 C GLY 268 ? C GLY 194 
210 1 Y 1 C LEU 269 ? C LEU 195 
211 1 Y 1 C ASP 270 ? C ASP 196 
212 1 Y 1 C MET 271 ? C MET 197 
213 1 Y 1 C ASP 272 ? C ASP 198 
214 1 Y 1 C VAL 273 ? C VAL 199 
215 1 Y 1 C GLY 274 ? C GLY 200 
216 1 Y 1 C LYS 275 ? C LYS 201 
217 1 Y 1 C GLN 276 ? C GLN 202 
218 1 Y 1 C ARG 430 ? C ARG 356 
219 1 Y 1 C LYS 431 ? C LYS 357 
220 1 Y 1 C LYS 432 ? C LYS 358 
221 1 Y 1 C GLN 433 ? C GLN 359 
222 1 Y 1 C ALA 434 ? C ALA 360 
223 1 Y 1 C HIS 435 ? C HIS 361 
224 1 Y 1 C PHE 436 ? C PHE 362 
225 1 Y 1 C GLU 437 ? C GLU 363 
226 1 Y 1 C LEU 438 ? C LEU 364 
227 1 Y 1 C GLY 439 ? C GLY 365 
228 1 Y 1 C LEU 440 ? C LEU 366 
229 1 Y 1 C GLU 441 ? C GLU 367 
230 1 Y 1 C HIS 442 ? C HIS 368 
231 1 Y 1 C HIS 443 ? C HIS 369 
232 1 Y 1 C HIS 444 ? C HIS 370 
233 1 Y 1 C HIS 445 ? C HIS 371 
234 1 Y 1 C HIS 446 ? C HIS 372 
235 1 Y 1 C HIS 447 ? C HIS 373 
236 1 Y 1 D MET 75  ? D MET 1   
237 1 Y 1 D PRO 76  ? D PRO 2   
238 1 Y 1 D SER 77  ? D SER 3   
239 1 Y 1 D PRO 78  ? D PRO 4   
240 1 Y 1 D VAL 79  ? D VAL 5   
241 1 Y 1 D THR 80  ? D THR 6   
242 1 Y 1 D THR 81  ? D THR 7   
243 1 Y 1 D PHE 82  ? D PHE 8   
244 1 Y 1 D GLY 83  ? D GLY 9   
245 1 Y 1 D PRO 84  ? D PRO 10  
246 1 Y 1 D LYS 85  ? D LYS 11  
247 1 Y 1 D ALA 86  ? D ALA 12  
248 1 Y 1 D THR 87  ? D THR 13  
249 1 Y 1 D VAL 88  ? D VAL 14  
250 1 Y 1 D GLU 89  ? D GLU 15  
251 1 Y 1 D THR 90  ? D THR 16  
252 1 Y 1 D GLN 91  ? D GLN 17  
253 1 Y 1 D ASP 92  ? D ASP 18  
254 1 Y 1 D PRO 93  ? D PRO 19  
255 1 Y 1 D ALA 94  ? D ALA 20  
256 1 Y 1 D THR 163 ? D THR 89  
257 1 Y 1 D PHE 164 ? D PHE 90  
258 1 Y 1 D ARG 165 ? D ARG 91  
259 1 Y 1 D GLU 166 ? D GLU 92  
260 1 Y 1 D ASP 167 ? D ASP 93  
261 1 Y 1 D TYR 168 ? D TYR 94  
262 1 Y 1 D ASP 169 ? D ASP 95  
263 1 Y 1 D ASP 170 ? D ASP 96  
264 1 Y 1 D ILE 171 ? D ILE 97  
265 1 Y 1 D SER 172 ? D SER 98  
266 1 Y 1 D LEU 248 ? D LEU 174 
267 1 Y 1 D ARG 249 ? D ARG 175 
268 1 Y 1 D GLY 250 ? D GLY 176 
269 1 Y 1 D LYS 251 ? D LYS 177 
270 1 Y 1 D LYS 252 ? D LYS 178 
271 1 Y 1 D THR 253 ? D THR 179 
272 1 Y 1 D ALA 254 ? D ALA 180 
273 1 Y 1 D VAL 255 ? D VAL 181 
274 1 Y 1 D HIS 256 ? D HIS 182 
275 1 Y 1 D ASN 257 ? D ASN 183 
276 1 Y 1 D GLY 258 ? D GLY 184 
277 1 Y 1 D LEU 259 ? D LEU 185 
278 1 Y 1 D GLY 260 ? D GLY 186 
279 1 Y 1 D GLU 261 ? D GLU 187 
280 1 Y 1 D ASN 262 ? D ASN 188 
281 1 Y 1 D GLY 263 ? D GLY 189 
282 1 Y 1 D SER 264 ? D SER 190 
283 1 Y 1 D GLN 265 ? D GLN 191 
284 1 Y 1 D ALA 266 ? D ALA 192 
285 1 Y 1 D ALA 267 ? D ALA 193 
286 1 Y 1 D GLY 268 ? D GLY 194 
287 1 Y 1 D LEU 269 ? D LEU 195 
288 1 Y 1 D ASP 270 ? D ASP 196 
289 1 Y 1 D MET 271 ? D MET 197 
290 1 Y 1 D ASP 272 ? D ASP 198 
291 1 Y 1 D VAL 273 ? D VAL 199 
292 1 Y 1 D GLY 274 ? D GLY 200 
293 1 Y 1 D LYS 275 ? D LYS 201 
294 1 Y 1 D GLN 276 ? D GLN 202 
295 1 Y 1 D VAL 429 ? D VAL 355 
296 1 Y 1 D ARG 430 ? D ARG 356 
297 1 Y 1 D LYS 431 ? D LYS 357 
298 1 Y 1 D LYS 432 ? D LYS 358 
299 1 Y 1 D GLN 433 ? D GLN 359 
300 1 Y 1 D ALA 434 ? D ALA 360 
301 1 Y 1 D HIS 435 ? D HIS 361 
302 1 Y 1 D PHE 436 ? D PHE 362 
303 1 Y 1 D GLU 437 ? D GLU 363 
304 1 Y 1 D LEU 438 ? D LEU 364 
305 1 Y 1 D GLY 439 ? D GLY 365 
306 1 Y 1 D LEU 440 ? D LEU 366 
307 1 Y 1 D GLU 441 ? D GLU 367 
308 1 Y 1 D HIS 442 ? D HIS 368 
309 1 Y 1 D HIS 443 ? D HIS 369 
310 1 Y 1 D HIS 444 ? D HIS 370 
311 1 Y 1 D HIS 445 ? D HIS 371 
312 1 Y 1 D HIS 446 ? D HIS 372 
313 1 Y 1 D HIS 447 ? D HIS 373 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-20 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9CR4 
_em_admin.last_update        2025-02-12 
_em_admin.map_release_date   2025-01-08 
_em_admin.title              'CryoEM Structure of the C-terminally truncated form of human NAD Kinase' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 50 mM ? 1 TRIS 
1 50 mM ? 2 NaCl 
1 2  mM ? 3 DTT  
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                49 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               'BL21(DE3)' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     6732 
# 
_em_particle_selection.details                  'template based picking using a low resolution map' 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   4587353 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC       ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 SerialEM        4 
MASKING                    ? 3  ? ? ? ?               ? 
'CTF CORRECTION'           ? 4  1 ? ? cryoSPARC       ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?               ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?               ? 
'MODEL FITTING'            ? 7  ? 1 ? 'UCSF ChimeraX' ? 
OTHER                      ? 8  ? ? ? ?               ? 
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX          ? 
'MODEL REFINEMENT'         ? 10 ? 1 ? Coot            ? 
'INITIAL EULER ASSIGNMENT' ? 11 1 ? ? cryoSPARC       ? 
'FINAL EULER ASSIGNMENT'   ? 12 1 ? ? cryoSPARC       ? 
CLASSIFICATION             ? 13 1 ? ? cryoSPARC       ? 
RECONSTRUCTION             ? 14 1 ? ? cryoSPARC       ? 
# 
_em_specimen.concentration           0.3 
_em_specimen.details                 'Purified by FPLC. Monodispersed.' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Cancer Institute (NIH/NCI)' 'United States' R01GM143236      1 
'Welch Foundation'                                                  'United States' I-2067-20210327  2 
'Welch Foundation'                                                  'United States' I-2067-20240404  3 
'Agence Nationale de la Recherche (ANR)'                            France          ANR-20-CE18-0025 4 
'Fondation pour la Recherche Medicale (FRM)'                        France          EQU202303016265  5 
# 
_atom_sites.entry_id                    9CR4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . SER A 1 21  ? 137.458 94.443  126.175 1.00 117.17 ? 95  SER A N   1 
ATOM 2    C CA  . SER A 1 21  ? 138.896 94.207  126.139 1.00 116.99 ? 95  SER A CA  1 
ATOM 3    C C   . SER A 1 21  ? 139.247 93.088  125.164 1.00 115.12 ? 95  SER A C   1 
ATOM 4    O O   . SER A 1 21  ? 140.048 92.208  125.480 1.00 114.21 ? 95  SER A O   1 
ATOM 5    C CB  . SER A 1 21  ? 139.419 93.868  127.536 1.00 118.14 ? 95  SER A CB  1 
ATOM 6    O OG  . SER A 1 21  ? 138.804 92.696  128.041 1.00 119.57 ? 95  SER A OG  1 
ATOM 7    N N   . VAL A 1 22  ? 138.636 93.124  123.980 1.00 116.18 ? 96  VAL A N   1 
ATOM 8    C CA  . VAL A 1 22  ? 138.915 92.145  122.935 1.00 119.05 ? 96  VAL A CA  1 
ATOM 9    C C   . VAL A 1 22  ? 140.363 92.306  122.496 1.00 120.51 ? 96  VAL A C   1 
ATOM 10   O O   . VAL A 1 22  ? 140.777 93.392  122.077 1.00 120.07 ? 96  VAL A O   1 
ATOM 11   C CB  . VAL A 1 22  ? 137.952 92.304  121.745 1.00 120.86 ? 96  VAL A CB  1 
ATOM 12   C CG1 . VAL A 1 22  ? 138.260 91.270  120.671 1.00 120.20 ? 96  VAL A CG1 1 
ATOM 13   C CG2 . VAL A 1 22  ? 136.509 92.190  122.211 1.00 118.63 ? 96  VAL A CG2 1 
ATOM 14   N N   . ARG A 1 23  ? 141.143 91.229  122.584 1.00 119.14 ? 97  ARG A N   1 
ATOM 15   C CA  . ARG A 1 23  ? 142.574 91.344  122.342 1.00 117.87 ? 97  ARG A CA  1 
ATOM 16   C C   . ARG A 1 23  ? 142.901 91.331  120.854 1.00 116.82 ? 97  ARG A C   1 
ATOM 17   O O   . ARG A 1 23  ? 143.329 92.352  120.308 1.00 117.22 ? 97  ARG A O   1 
ATOM 18   C CB  . ARG A 1 23  ? 143.319 90.212  123.054 1.00 116.66 ? 97  ARG A CB  1 
ATOM 19   C CG  . ARG A 1 23  ? 144.794 90.485  123.294 1.00 116.29 ? 97  ARG A CG  1 
ATOM 20   C CD  . ARG A 1 23  ? 145.016 91.857  123.911 1.00 117.09 ? 97  ARG A CD  1 
ATOM 21   N NE  . ARG A 1 23  ? 146.431 92.203  123.971 1.00 118.33 ? 97  ARG A NE  1 
ATOM 22   C CZ  . ARG A 1 23  ? 146.905 93.343  124.455 1.00 117.32 ? 97  ARG A CZ  1 
ATOM 23   N NH1 . ARG A 1 23  ? 146.100 94.281  124.927 1.00 114.98 ? 97  ARG A NH1 1 
ATOM 24   N NH2 . ARG A 1 23  ? 148.219 93.547  124.465 1.00 117.63 ? 97  ARG A NH2 1 
ATOM 25   N N   . LEU A 1 24  ? 142.655 90.205  120.185 1.00 117.49 ? 98  LEU A N   1 
ATOM 26   C CA  . LEU A 1 24  ? 142.993 90.034  118.775 1.00 119.31 ? 98  LEU A CA  1 
ATOM 27   C C   . LEU A 1 24  ? 142.625 88.620  118.352 1.00 119.42 ? 98  LEU A C   1 
ATOM 28   O O   . LEU A 1 24  ? 142.449 87.736  119.195 1.00 119.13 ? 98  LEU A O   1 
ATOM 29   C CB  . LEU A 1 24  ? 144.484 90.297  118.515 1.00 118.10 ? 98  LEU A CB  1 
ATOM 30   C CG  . LEU A 1 24  ? 144.941 90.462  117.065 1.00 117.48 ? 98  LEU A CG  1 
ATOM 31   C CD1 . LEU A 1 24  ? 144.097 91.509  116.357 1.00 116.53 ? 98  LEU A CD1 1 
ATOM 32   C CD2 . LEU A 1 24  ? 146.411 90.839  117.016 1.00 116.14 ? 98  LEU A CD2 1 
ATOM 33   N N   . THR A 1 25  ? 142.512 88.418  117.039 1.00 119.36 ? 99  THR A N   1 
ATOM 34   C CA  . THR A 1 25  ? 142.294 87.094  116.464 1.00 118.80 ? 99  THR A CA  1 
ATOM 35   C C   . THR A 1 25  ? 142.793 87.101  115.027 1.00 117.25 ? 99  THR A C   1 
ATOM 36   O O   . THR A 1 25  ? 142.207 87.769  114.171 1.00 116.20 ? 99  THR A O   1 
ATOM 37   C CB  . THR A 1 25  ? 140.816 86.696  116.513 1.00 118.77 ? 99  THR A CB  1 
ATOM 38   O OG1 . THR A 1 25  ? 140.371 86.660  117.875 1.00 117.68 ? 99  THR A OG1 1 
ATOM 39   C CG2 . THR A 1 25  ? 140.616 85.325  115.887 1.00 117.07 ? 99  THR A CG2 1 
ATOM 40   N N   . TRP A 1 26  ? 143.870 86.359  114.763 1.00 108.17 ? 100 TRP A N   1 
ATOM 41   C CA  . TRP A 1 26  ? 144.438 86.261  113.422 1.00 106.93 ? 100 TRP A CA  1 
ATOM 42   C C   . TRP A 1 26  ? 144.066 84.973  112.702 1.00 106.35 ? 100 TRP A C   1 
ATOM 43   O O   . TRP A 1 26  ? 143.980 84.970  111.470 1.00 105.53 ? 100 TRP A O   1 
ATOM 44   C CB  . TRP A 1 26  ? 145.966 86.372  113.470 1.00 103.75 ? 100 TRP A CB  1 
ATOM 45   C CG  . TRP A 1 26  ? 146.487 87.774  113.542 1.00 104.21 ? 100 TRP A CG  1 
ATOM 46   C CD1 . TRP A 1 26  ? 147.340 88.281  114.476 1.00 103.81 ? 100 TRP A CD1 1 
ATOM 47   C CD2 . TRP A 1 26  ? 146.189 88.852  112.645 1.00 105.54 ? 100 TRP A CD2 1 
ATOM 48   N NE1 . TRP A 1 26  ? 147.595 89.604  114.216 1.00 102.32 ? 100 TRP A NE1 1 
ATOM 49   C CE2 . TRP A 1 26  ? 146.898 89.980  113.099 1.00 105.02 ? 100 TRP A CE2 1 
ATOM 50   C CE3 . TRP A 1 26  ? 145.391 88.973  111.504 1.00 106.02 ? 100 TRP A CE3 1 
ATOM 51   C CZ2 . TRP A 1 26  ? 146.833 91.212  112.454 1.00 106.44 ? 100 TRP A CZ2 1 
ATOM 52   C CZ3 . TRP A 1 26  ? 145.328 90.197  110.865 1.00 104.71 ? 100 TRP A CZ3 1 
ATOM 53   C CH2 . TRP A 1 26  ? 146.044 91.300  111.341 1.00 104.10 ? 100 TRP A CH2 1 
ATOM 54   N N   . ASN A 1 27  ? 143.871 83.877  113.440 1.00 111.51 ? 101 ASN A N   1 
ATOM 55   C CA  . ASN A 1 27  ? 143.589 82.564  112.866 1.00 111.78 ? 101 ASN A CA  1 
ATOM 56   C C   . ASN A 1 27  ? 144.767 82.095  112.021 1.00 111.55 ? 101 ASN A C   1 
ATOM 57   O O   . ASN A 1 27  ? 145.455 81.134  112.382 1.00 112.19 ? 101 ASN A O   1 
ATOM 58   C CB  . ASN A 1 27  ? 142.296 82.586  112.043 1.00 111.30 ? 101 ASN A CB  1 
ATOM 59   C CG  . ASN A 1 27  ? 142.063 81.293  111.287 1.00 111.06 ? 101 ASN A CG  1 
ATOM 60   O OD1 . ASN A 1 27  ? 141.949 81.291  110.061 1.00 111.21 ? 101 ASN A OD1 1 
ATOM 61   N ND2 . ASN A 1 27  ? 141.991 80.185  112.015 1.00 110.57 ? 101 ASN A ND2 1 
ATOM 62   N N   . LYS A 1 28  ? 145.008 82.766  110.898 1.00 106.21 ? 102 LYS A N   1 
ATOM 63   C CA  . LYS A 1 28  ? 146.170 82.521  110.055 1.00 106.05 ? 102 LYS A CA  1 
ATOM 64   C C   . LYS A 1 28  ? 147.063 83.752  110.089 1.00 105.99 ? 102 LYS A C   1 
ATOM 65   O O   . LYS A 1 28  ? 146.566 84.878  110.206 1.00 105.28 ? 102 LYS A O   1 
ATOM 66   C CB  . LYS A 1 28  ? 145.757 82.198  108.616 1.00 105.62 ? 102 LYS A CB  1 
ATOM 67   C CG  . LYS A 1 28  ? 144.873 80.969  108.482 1.00 105.38 ? 102 LYS A CG  1 
ATOM 68   C CD  . LYS A 1 28  ? 144.443 80.756  107.039 1.00 106.04 ? 102 LYS A CD  1 
ATOM 69   C CE  . LYS A 1 28  ? 143.513 79.559  106.909 1.00 104.85 ? 102 LYS A CE  1 
ATOM 70   N NZ  . LYS A 1 28  ? 144.142 78.308  107.413 1.00 104.84 ? 102 LYS A NZ  1 
ATOM 71   N N   . SER A 1 29  ? 148.375 83.536  109.995 1.00 100.14 ? 103 SER A N   1 
ATOM 72   C CA  . SER A 1 29  ? 149.346 84.621  110.058 1.00 97.93  ? 103 SER A CA  1 
ATOM 73   C C   . SER A 1 29  ? 149.082 85.619  108.938 1.00 96.20  ? 103 SER A C   1 
ATOM 74   O O   . SER A 1 29  ? 148.725 85.217  107.823 1.00 95.25  ? 103 SER A O   1 
ATOM 75   C CB  . SER A 1 29  ? 150.772 84.075  109.963 1.00 95.61  ? 103 SER A CB  1 
ATOM 76   O OG  . SER A 1 29  ? 150.990 83.437  108.717 1.00 95.82  ? 103 SER A OG  1 
ATOM 77   N N   . PRO A 1 30  ? 149.227 86.918  109.195 1.00 90.54  ? 104 PRO A N   1 
ATOM 78   C CA  . PRO A 1 30  ? 148.916 87.909  108.160 1.00 90.61  ? 104 PRO A CA  1 
ATOM 79   C C   . PRO A 1 30  ? 149.857 87.794  106.971 1.00 95.70  ? 104 PRO A C   1 
ATOM 80   O O   . PRO A 1 30  ? 151.051 87.521  107.114 1.00 96.14  ? 104 PRO A O   1 
ATOM 81   C CB  . PRO A 1 30  ? 149.091 89.245  108.888 1.00 87.05  ? 104 PRO A CB  1 
ATOM 82   C CG  . PRO A 1 30  ? 150.089 88.953  109.945 1.00 85.36  ? 104 PRO A CG  1 
ATOM 83   C CD  . PRO A 1 30  ? 149.835 87.536  110.385 1.00 88.58  ? 104 PRO A CD  1 
ATOM 84   N N   . LYS A 1 31  ? 149.296 88.001  105.781 1.00 98.52  ? 105 LYS A N   1 
ATOM 85   C CA  . LYS A 1 31  ? 150.063 87.962  104.542 1.00 95.28  ? 105 LYS A CA  1 
ATOM 86   C C   . LYS A 1 31  ? 149.778 89.120  103.600 1.00 94.29  ? 105 LYS A C   1 
ATOM 87   O O   . LYS A 1 31  ? 150.620 89.403  102.739 1.00 92.07  ? 105 LYS A O   1 
ATOM 88   C CB  . LYS A 1 31  ? 149.801 86.642  103.815 1.00 94.17  ? 105 LYS A CB  1 
ATOM 89   C CG  . LYS A 1 31  ? 150.335 85.417  104.538 1.00 94.39  ? 105 LYS A CG  1 
ATOM 90   C CD  . LYS A 1 31  ? 150.020 84.142  103.775 1.00 95.08  ? 105 LYS A CD  1 
ATOM 91   C CE  . LYS A 1 31  ? 150.575 82.919  104.486 1.00 94.60  ? 105 LYS A CE  1 
ATOM 92   N NZ  . LYS A 1 31  ? 150.252 81.660  103.760 1.00 95.06  ? 105 LYS A NZ  1 
ATOM 93   N N   . SER A 1 32  ? 148.638 89.793  103.723 1.00 84.84  ? 106 SER A N   1 
ATOM 94   C CA  . SER A 1 32  ? 148.271 90.897  102.847 1.00 80.99  ? 106 SER A CA  1 
ATOM 95   C C   . SER A 1 32  ? 148.119 92.164  103.673 1.00 77.34  ? 106 SER A C   1 
ATOM 96   O O   . SER A 1 32  ? 147.456 92.155  104.716 1.00 82.07  ? 106 SER A O   1 
ATOM 97   C CB  . SER A 1 32  ? 146.972 90.596  102.093 1.00 85.25  ? 106 SER A CB  1 
ATOM 98   O OG  . SER A 1 32  ? 146.534 91.727  101.361 1.00 86.30  ? 106 SER A OG  1 
ATOM 99   N N   . VAL A 1 33  ? 148.733 93.247  103.208 1.00 62.39  ? 107 VAL A N   1 
ATOM 100  C CA  . VAL A 1 33  ? 148.685 94.539  103.879 1.00 68.65  ? 107 VAL A CA  1 
ATOM 101  C C   . VAL A 1 33  ? 148.257 95.587  102.865 1.00 69.94  ? 107 VAL A C   1 
ATOM 102  O O   . VAL A 1 33  ? 148.860 95.700  101.792 1.00 74.44  ? 107 VAL A O   1 
ATOM 103  C CB  . VAL A 1 33  ? 150.045 94.911  104.500 1.00 69.00  ? 107 VAL A CB  1 
ATOM 104  C CG1 . VAL A 1 33  ? 150.024 96.340  105.007 1.00 70.99  ? 107 VAL A CG1 1 
ATOM 105  C CG2 . VAL A 1 33  ? 150.394 93.953  105.625 1.00 70.81  ? 107 VAL A CG2 1 
ATOM 106  N N   . LEU A 1 34  ? 147.222 96.351  103.201 1.00 56.24  ? 108 LEU A N   1 
ATOM 107  C CA  . LEU A 1 34  ? 146.747 97.439  102.358 1.00 45.03  ? 108 LEU A CA  1 
ATOM 108  C C   . LEU A 1 34  ? 147.142 98.764  102.995 1.00 50.60  ? 108 LEU A C   1 
ATOM 109  O O   . LEU A 1 34  ? 146.547 99.177  103.996 1.00 59.28  ? 108 LEU A O   1 
ATOM 110  C CB  . LEU A 1 34  ? 145.235 97.366  102.165 1.00 43.12  ? 108 LEU A CB  1 
ATOM 111  C CG  . LEU A 1 34  ? 144.629 98.512  101.358 1.00 58.56  ? 108 LEU A CG  1 
ATOM 112  C CD1 . LEU A 1 34  ? 145.208 98.541  99.953  1.00 59.76  ? 108 LEU A CD1 1 
ATOM 113  C CD2 . LEU A 1 34  ? 143.116 98.391  101.312 1.00 60.63  ? 108 LEU A CD2 1 
ATOM 114  N N   . VAL A 1 35  ? 148.139 99.425  102.417 1.00 51.09  ? 109 VAL A N   1 
ATOM 115  C CA  . VAL A 1 35  ? 148.646 100.691 102.932 1.00 46.49  ? 109 VAL A CA  1 
ATOM 116  C C   . VAL A 1 35  ? 147.964 101.820 102.177 1.00 52.42  ? 109 VAL A C   1 
ATOM 117  O O   . VAL A 1 35  ? 148.034 101.888 100.943 1.00 66.55  ? 109 VAL A O   1 
ATOM 118  C CB  . VAL A 1 35  ? 150.172 100.783 102.801 1.00 55.99  ? 109 VAL A CB  1 
ATOM 119  C CG1 . VAL A 1 35  ? 150.666 102.095 103.382 1.00 60.09  ? 109 VAL A CG1 1 
ATOM 120  C CG2 . VAL A 1 35  ? 150.829 99.608  103.495 1.00 58.14  ? 109 VAL A CG2 1 
ATOM 121  N N   . ILE A 1 36  ? 147.305 102.705 102.917 1.00 51.11  ? 110 ILE A N   1 
ATOM 122  C CA  . ILE A 1 36  ? 146.549 103.814 102.355 1.00 51.59  ? 110 ILE A CA  1 
ATOM 123  C C   . ILE A 1 36  ? 147.082 105.101 102.964 1.00 55.71  ? 110 ILE A C   1 
ATOM 124  O O   . ILE A 1 36  ? 147.154 105.228 104.191 1.00 62.29  ? 110 ILE A O   1 
ATOM 125  C CB  . ILE A 1 36  ? 145.043 103.662 102.629 1.00 49.34  ? 110 ILE A CB  1 
ATOM 126  C CG1 . ILE A 1 36  ? 144.512 102.388 101.976 1.00 49.48  ? 110 ILE A CG1 1 
ATOM 127  C CG2 . ILE A 1 36  ? 144.287 104.875 102.127 1.00 57.01  ? 110 ILE A CG2 1 
ATOM 128  C CD1 . ILE A 1 36  ? 143.120 102.021 102.406 1.00 51.09  ? 110 ILE A CD1 1 
ATOM 129  N N   . LYS A 1 37  ? 147.453 106.047 102.111 1.00 75.84  ? 111 LYS A N   1 
ATOM 130  C CA  . LYS A 1 37  ? 148.010 107.319 102.539 1.00 79.16  ? 111 LYS A CA  1 
ATOM 131  C C   . LYS A 1 37  ? 147.041 108.438 102.180 1.00 86.99  ? 111 LYS A C   1 
ATOM 132  O O   . LYS A 1 37  ? 146.246 108.314 101.245 1.00 89.69  ? 111 LYS A O   1 
ATOM 133  C CB  . LYS A 1 37  ? 149.378 107.560 101.891 1.00 86.78  ? 111 LYS A CB  1 
ATOM 134  C CG  . LYS A 1 37  ? 150.191 108.684 102.507 1.00 88.47  ? 111 LYS A CG  1 
ATOM 135  C CD  . LYS A 1 37  ? 151.565 108.766 101.863 1.00 88.58  ? 111 LYS A CD  1 
ATOM 136  C CE  . LYS A 1 37  ? 151.457 109.066 100.377 1.00 84.78  ? 111 LYS A CE  1 
ATOM 137  N NZ  . LYS A 1 37  ? 152.793 109.166 99.733  1.00 86.66  ? 111 LYS A NZ  1 
ATOM 138  N N   . LYS A 1 38  ? 147.106 109.533 102.943 1.00 100.33 ? 112 LYS A N   1 
ATOM 139  C CA  . LYS A 1 38  ? 146.182 110.643 102.729 1.00 103.94 ? 112 LYS A CA  1 
ATOM 140  C C   . LYS A 1 38  ? 146.387 111.299 101.368 1.00 102.82 ? 112 LYS A C   1 
ATOM 141  O O   . LYS A 1 38  ? 145.462 111.926 100.838 1.00 101.97 ? 112 LYS A O   1 
ATOM 142  C CB  . LYS A 1 38  ? 146.338 111.673 103.852 1.00 102.49 ? 112 LYS A CB  1 
ATOM 143  C CG  . LYS A 1 38  ? 145.365 112.842 103.783 1.00 101.75 ? 112 LYS A CG  1 
ATOM 144  C CD  . LYS A 1 38  ? 145.621 113.847 104.893 1.00 100.88 ? 112 LYS A CD  1 
ATOM 145  C CE  . LYS A 1 38  ? 145.415 113.218 106.261 1.00 99.93  ? 112 LYS A CE  1 
ATOM 146  N NZ  . LYS A 1 38  ? 145.664 114.184 107.365 1.00 98.79  ? 112 LYS A NZ  1 
ATOM 147  N N   . MET A 1 39  ? 147.583 111.161 100.789 1.00 111.35 ? 113 MET A N   1 
ATOM 148  C CA  . MET A 1 39  ? 147.939 111.744 99.496  1.00 112.57 ? 113 MET A CA  1 
ATOM 149  C C   . MET A 1 39  ? 147.894 113.267 99.527  1.00 113.32 ? 113 MET A C   1 
ATOM 150  O O   . MET A 1 39  ? 147.464 113.866 100.519 1.00 112.69 ? 113 MET A O   1 
ATOM 151  C CB  . MET A 1 39  ? 147.029 111.217 98.379  1.00 111.05 ? 113 MET A CB  1 
ATOM 152  C CG  . MET A 1 39  ? 146.812 109.712 98.390  1.00 110.72 ? 113 MET A CG  1 
ATOM 153  S SD  . MET A 1 39  ? 148.315 108.777 98.727  1.00 118.93 ? 113 MET A SD  1 
ATOM 154  C CE  . MET A 1 39  ? 149.345 109.252 97.340  1.00 111.25 ? 113 MET A CE  1 
ATOM 155  N N   . ARG A 1 40  ? 148.349 113.897 98.441  1.00 113.48 ? 114 ARG A N   1 
ATOM 156  C CA  . ARG A 1 40  ? 148.366 115.355 98.315  1.00 113.79 ? 114 ARG A CA  1 
ATOM 157  C C   . ARG A 1 40  ? 149.128 116.006 99.467  1.00 112.66 ? 114 ARG A C   1 
ATOM 158  O O   . ARG A 1 40  ? 148.770 117.085 99.943  1.00 112.91 ? 114 ARG A O   1 
ATOM 159  C CB  . ARG A 1 40  ? 146.947 115.920 98.218  1.00 114.03 ? 114 ARG A CB  1 
ATOM 160  C CG  . ARG A 1 40  ? 146.209 115.540 96.946  1.00 113.23 ? 114 ARG A CG  1 
ATOM 161  C CD  . ARG A 1 40  ? 144.830 116.178 96.904  1.00 112.71 ? 114 ARG A CD  1 
ATOM 162  N NE  . ARG A 1 40  ? 144.077 115.770 95.724  1.00 114.53 ? 114 ARG A NE  1 
ATOM 163  C CZ  . ARG A 1 40  ? 142.810 116.085 95.496  1.00 115.74 ? 114 ARG A CZ  1 
ATOM 164  N NH1 . ARG A 1 40  ? 142.116 116.818 96.352  1.00 115.57 ? 114 ARG A NH1 1 
ATOM 165  N NH2 . ARG A 1 40  ? 142.224 115.656 94.382  1.00 114.03 ? 114 ARG A NH2 1 
ATOM 166  N N   . ASP A 1 41  ? 150.190 115.345 99.921  1.00 102.50 ? 115 ASP A N   1 
ATOM 167  C CA  . ASP A 1 41  ? 150.995 115.858 101.024 1.00 102.19 ? 115 ASP A CA  1 
ATOM 168  C C   . ASP A 1 41  ? 152.430 115.400 100.831 1.00 105.12 ? 115 ASP A C   1 
ATOM 169  O O   . ASP A 1 41  ? 152.710 114.198 100.884 1.00 105.95 ? 115 ASP A O   1 
ATOM 170  C CB  . ASP A 1 41  ? 150.450 115.381 102.372 1.00 102.97 ? 115 ASP A CB  1 
ATOM 171  C CG  . ASP A 1 41  ? 151.104 116.082 103.547 1.00 104.76 ? 115 ASP A CG  1 
ATOM 172  O OD1 . ASP A 1 41  ? 151.886 117.029 103.321 1.00 103.46 ? 115 ASP A OD1 1 
ATOM 173  O OD2 . ASP A 1 41  ? 150.834 115.685 104.701 1.00 103.93 ? 115 ASP A OD2 1 
ATOM 174  N N   . ALA A 1 42  ? 153.333 116.356 100.606 1.00 104.02 ? 116 ALA A N   1 
ATOM 175  C CA  . ALA A 1 42  ? 154.743 116.018 100.443 1.00 104.00 ? 116 ALA A CA  1 
ATOM 176  C C   . ALA A 1 42  ? 155.331 115.464 101.734 1.00 102.38 ? 116 ALA A C   1 
ATOM 177  O O   . ALA A 1 42  ? 156.224 114.610 101.700 1.00 100.93 ? 116 ALA A O   1 
ATOM 178  C CB  . ALA A 1 42  ? 155.527 117.244 99.977  1.00 102.64 ? 116 ALA A CB  1 
ATOM 179  N N   . SER A 1 43  ? 154.840 115.937 102.882 1.00 98.68  ? 117 SER A N   1 
ATOM 180  C CA  . SER A 1 43  ? 155.368 115.487 104.164 1.00 99.85  ? 117 SER A CA  1 
ATOM 181  C C   . SER A 1 43  ? 155.157 113.997 104.389 1.00 100.48 ? 117 SER A C   1 
ATOM 182  O O   . SER A 1 43  ? 155.914 113.384 105.148 1.00 101.76 ? 117 SER A O   1 
ATOM 183  C CB  . SER A 1 43  ? 154.724 116.278 105.304 1.00 100.56 ? 117 SER A CB  1 
ATOM 184  O OG  . SER A 1 43  ? 155.213 115.848 106.562 1.00 98.95  ? 117 SER A OG  1 
ATOM 185  N N   . LEU A 1 44  ? 154.149 113.402 103.754 1.00 98.51  ? 118 LEU A N   1 
ATOM 186  C CA  . LEU A 1 44  ? 153.890 111.977 103.895 1.00 98.45  ? 118 LEU A CA  1 
ATOM 187  C C   . LEU A 1 44  ? 154.602 111.132 102.848 1.00 100.22 ? 118 LEU A C   1 
ATOM 188  O O   . LEU A 1 44  ? 154.537 109.900 102.925 1.00 103.31 ? 118 LEU A O   1 
ATOM 189  C CB  . LEU A 1 44  ? 152.384 111.704 103.825 1.00 98.76  ? 118 LEU A CB  1 
ATOM 190  C CG  . LEU A 1 44  ? 151.512 112.425 104.853 1.00 101.94 ? 118 LEU A CG  1 
ATOM 191  C CD1 . LEU A 1 44  ? 150.046 112.074 104.653 1.00 99.96  ? 118 LEU A CD1 1 
ATOM 192  C CD2 . LEU A 1 44  ? 151.960 112.085 106.265 1.00 99.06  ? 118 LEU A CD2 1 
ATOM 193  N N   . LEU A 1 45  ? 155.271 111.755 101.875 1.00 103.03 ? 119 LEU A N   1 
ATOM 194  C CA  . LEU A 1 45  ? 155.938 110.985 100.829 1.00 104.18 ? 119 LEU A CA  1 
ATOM 195  C C   . LEU A 1 45  ? 157.108 110.185 101.390 1.00 104.40 ? 119 LEU A C   1 
ATOM 196  O O   . LEU A 1 45  ? 157.211 108.975 101.158 1.00 103.19 ? 119 LEU A O   1 
ATOM 197  C CB  . LEU A 1 45  ? 156.413 111.918 99.714  1.00 104.50 ? 119 LEU A CB  1 
ATOM 198  C CG  . LEU A 1 45  ? 155.343 112.699 98.950  1.00 105.73 ? 119 LEU A CG  1 
ATOM 199  C CD1 . LEU A 1 45  ? 155.982 113.574 97.883  1.00 103.21 ? 119 LEU A CD1 1 
ATOM 200  C CD2 . LEU A 1 45  ? 154.325 111.756 98.330  1.00 105.30 ? 119 LEU A CD2 1 
ATOM 201  N N   . GLN A 1 46  ? 157.999 110.844 102.129 1.00 106.05 ? 120 GLN A N   1 
ATOM 202  C CA  . GLN A 1 46  ? 159.178 110.156 102.654 1.00 105.75 ? 120 GLN A CA  1 
ATOM 203  C C   . GLN A 1 46  ? 158.833 109.064 103.661 1.00 104.54 ? 120 GLN A C   1 
ATOM 204  O O   . GLN A 1 46  ? 159.352 107.943 103.518 1.00 102.03 ? 120 GLN A O   1 
ATOM 205  C CB  . GLN A 1 46  ? 160.153 111.181 103.243 1.00 103.77 ? 120 GLN A CB  1 
ATOM 206  C CG  . GLN A 1 46  ? 161.383 110.566 103.887 1.00 104.19 ? 120 GLN A CG  1 
ATOM 207  C CD  . GLN A 1 46  ? 162.280 111.602 104.533 1.00 105.49 ? 120 GLN A CD  1 
ATOM 208  O OE1 . GLN A 1 46  ? 162.057 112.804 104.396 1.00 104.08 ? 120 GLN A OE1 1 
ATOM 209  N NE2 . GLN A 1 46  ? 163.303 111.139 105.243 1.00 106.03 ? 120 GLN A NE2 1 
ATOM 210  N N   . PRO A 1 47  ? 157.999 109.298 104.683 1.00 104.45 ? 121 PRO A N   1 
ATOM 211  C CA  . PRO A 1 47  ? 157.676 108.198 105.608 1.00 103.40 ? 121 PRO A CA  1 
ATOM 212  C C   . PRO A 1 47  ? 156.966 107.037 104.940 1.00 100.65 ? 121 PRO A C   1 
ATOM 213  O O   . PRO A 1 47  ? 157.051 105.905 105.431 1.00 101.61 ? 121 PRO A O   1 
ATOM 214  C CB  . PRO A 1 47  ? 156.786 108.875 106.660 1.00 103.25 ? 121 PRO A CB  1 
ATOM 215  C CG  . PRO A 1 47  ? 157.122 110.319 106.571 1.00 102.33 ? 121 PRO A CG  1 
ATOM 216  C CD  . PRO A 1 47  ? 157.387 110.564 105.124 1.00 103.61 ? 121 PRO A CD  1 
ATOM 217  N N   . PHE A 1 48  ? 156.262 107.284 103.834 1.00 92.38  ? 122 PHE A N   1 
ATOM 218  C CA  . PHE A 1 48  ? 155.624 106.194 103.105 1.00 95.28  ? 122 PHE A CA  1 
ATOM 219  C C   . PHE A 1 48  ? 156.659 105.222 102.556 1.00 96.71  ? 122 PHE A C   1 
ATOM 220  O O   . PHE A 1 48  ? 156.440 104.005 102.554 1.00 97.05  ? 122 PHE A O   1 
ATOM 221  C CB  . PHE A 1 48  ? 154.758 106.757 101.977 1.00 95.47  ? 122 PHE A CB  1 
ATOM 222  C CG  . PHE A 1 48  ? 154.110 105.704 101.124 1.00 90.39  ? 122 PHE A CG  1 
ATOM 223  C CD1 . PHE A 1 48  ? 152.979 105.042 101.561 1.00 90.57  ? 122 PHE A CD1 1 
ATOM 224  C CD2 . PHE A 1 48  ? 154.626 105.387 99.881  1.00 93.46  ? 122 PHE A CD2 1 
ATOM 225  C CE1 . PHE A 1 48  ? 152.381 104.078 100.781 1.00 88.99  ? 122 PHE A CE1 1 
ATOM 226  C CE2 . PHE A 1 48  ? 154.030 104.423 99.095  1.00 95.96  ? 122 PHE A CE2 1 
ATOM 227  C CZ  . PHE A 1 48  ? 152.904 103.770 99.546  1.00 92.54  ? 122 PHE A CZ  1 
ATOM 228  N N   . LYS A 1 49  ? 157.791 105.743 102.077 1.00 102.23 ? 123 LYS A N   1 
ATOM 229  C CA  . LYS A 1 49  ? 158.821 104.883 101.504 1.00 103.18 ? 123 LYS A CA  1 
ATOM 230  C C   . LYS A 1 49  ? 159.423 103.956 102.553 1.00 102.10 ? 123 LYS A C   1 
ATOM 231  O O   . LYS A 1 49  ? 159.646 102.769 102.288 1.00 100.69 ? 123 LYS A O   1 
ATOM 232  C CB  . LYS A 1 49  ? 159.910 105.735 100.853 1.00 104.01 ? 123 LYS A CB  1 
ATOM 233  C CG  . LYS A 1 49  ? 159.381 106.855 99.968  1.00 103.28 ? 123 LYS A CG  1 
ATOM 234  C CD  . LYS A 1 49  ? 158.491 106.316 98.858  1.00 103.19 ? 123 LYS A CD  1 
ATOM 235  C CE  . LYS A 1 49  ? 157.993 107.430 97.951  1.00 102.70 ? 123 LYS A CE  1 
ATOM 236  N NZ  . LYS A 1 49  ? 157.235 108.465 98.705  1.00 102.87 ? 123 LYS A NZ  1 
ATOM 237  N N   . GLU A 1 50  ? 159.699 104.480 103.750 1.00 100.66 ? 124 GLU A N   1 
ATOM 238  C CA  . GLU A 1 50  ? 160.351 103.674 104.778 1.00 99.35  ? 124 GLU A CA  1 
ATOM 239  C C   . GLU A 1 50  ? 159.469 102.513 105.220 1.00 98.87  ? 124 GLU A C   1 
ATOM 240  O O   . GLU A 1 50  ? 159.951 101.387 105.386 1.00 97.10  ? 124 GLU A O   1 
ATOM 241  C CB  . GLU A 1 50  ? 160.720 104.549 105.975 1.00 99.16  ? 124 GLU A CB  1 
ATOM 242  C CG  . GLU A 1 50  ? 161.670 105.685 105.643 1.00 100.88 ? 124 GLU A CG  1 
ATOM 243  C CD  . GLU A 1 50  ? 161.997 106.541 106.851 1.00 102.93 ? 124 GLU A CD  1 
ATOM 244  O OE1 . GLU A 1 50  ? 161.489 106.238 107.951 1.00 101.96 ? 124 GLU A OE1 1 
ATOM 245  O OE2 . GLU A 1 50  ? 162.760 107.518 106.700 1.00 102.64 ? 124 GLU A OE2 1 
ATOM 246  N N   . LEU A 1 51  ? 158.173 102.769 105.418 1.00 99.96  ? 125 LEU A N   1 
ATOM 247  C CA  . LEU A 1 51  ? 157.271 101.714 105.867 1.00 101.71 ? 125 LEU A CA  1 
ATOM 248  C C   . LEU A 1 51  ? 157.139 100.614 104.822 1.00 99.68  ? 125 LEU A C   1 
ATOM 249  O O   . LEU A 1 51  ? 157.140 99.425  105.160 1.00 100.52 ? 125 LEU A O   1 
ATOM 250  C CB  . LEU A 1 51  ? 155.899 102.301 106.201 1.00 103.43 ? 125 LEU A CB  1 
ATOM 251  C CG  . LEU A 1 51  ? 154.838 101.308 106.682 1.00 99.57  ? 125 LEU A CG  1 
ATOM 252  C CD1 . LEU A 1 51  ? 155.300 100.593 107.942 1.00 97.68  ? 125 LEU A CD1 1 
ATOM 253  C CD2 . LEU A 1 51  ? 153.514 102.013 106.918 1.00 95.91  ? 125 LEU A CD2 1 
ATOM 254  N N   . CYS A 1 52  ? 157.023 100.991 103.547 1.00 93.69  ? 126 CYS A N   1 
ATOM 255  C CA  . CYS A 1 52  ? 156.849 99.992  102.499 1.00 93.10  ? 126 CYS A CA  1 
ATOM 256  C C   . CYS A 1 52  ? 158.072 99.092  102.383 1.00 99.62  ? 126 CYS A C   1 
ATOM 257  O O   . CYS A 1 52  ? 157.941 97.893  102.113 1.00 101.40 ? 126 CYS A O   1 
ATOM 258  C CB  . CYS A 1 52  ? 156.553 100.674 101.165 1.00 92.52  ? 126 CYS A CB  1 
ATOM 259  S SG  . CYS A 1 52  ? 155.004 101.591 101.136 1.00 85.22  ? 126 CYS A SG  1 
ATOM 260  N N   . THR A 1 53  ? 159.268 99.651  102.581 1.00 102.07 ? 127 THR A N   1 
ATOM 261  C CA  . THR A 1 53  ? 160.478 98.838  102.530 1.00 97.79  ? 127 THR A CA  1 
ATOM 262  C C   . THR A 1 53  ? 160.476 97.778  103.623 1.00 96.60  ? 127 THR A C   1 
ATOM 263  O O   . THR A 1 53  ? 160.787 96.609  103.364 1.00 95.87  ? 127 THR A O   1 
ATOM 264  C CB  . THR A 1 53  ? 161.716 99.724  102.653 1.00 96.44  ? 127 THR A CB  1 
ATOM 265  O OG1 . THR A 1 53  ? 161.558 100.615 103.763 1.00 98.51  ? 127 THR A OG1 1 
ATOM 266  C CG2 . THR A 1 53  ? 161.917 100.535 101.384 1.00 95.32  ? 127 THR A CG2 1 
ATOM 267  N N   . HIS A 1 54  ? 160.126 98.164  104.852 1.00 103.83 ? 128 HIS A N   1 
ATOM 268  C CA  . HIS A 1 54  ? 160.106 97.199  105.946 1.00 106.91 ? 128 HIS A CA  1 
ATOM 269  C C   . HIS A 1 54  ? 159.010 96.160  105.750 1.00 108.01 ? 128 HIS A C   1 
ATOM 270  O O   . HIS A 1 54  ? 159.230 94.967  105.989 1.00 108.51 ? 128 HIS A O   1 
ATOM 271  C CB  . HIS A 1 54  ? 159.927 97.916  107.283 1.00 108.61 ? 128 HIS A CB  1 
ATOM 272  C CG  . HIS A 1 54  ? 159.833 96.987  108.454 1.00 108.78 ? 128 HIS A CG  1 
ATOM 273  N ND1 . HIS A 1 54  ? 158.629 96.575  108.983 1.00 106.62 ? 128 HIS A ND1 1 
ATOM 274  C CD2 . HIS A 1 54  ? 160.795 96.386  109.194 1.00 107.61 ? 128 HIS A CD2 1 
ATOM 275  C CE1 . HIS A 1 54  ? 158.853 95.761  109.999 1.00 105.48 ? 128 HIS A CE1 1 
ATOM 276  N NE2 . HIS A 1 54  ? 160.159 95.630  110.148 1.00 105.35 ? 128 HIS A NE2 1 
ATOM 277  N N   . LEU A 1 55  ? 157.821 96.593  105.325 1.00 103.11 ? 129 LEU A N   1 
ATOM 278  C CA  . LEU A 1 55  ? 156.740 95.645  105.074 1.00 100.65 ? 129 LEU A CA  1 
ATOM 279  C C   . LEU A 1 55  ? 157.104 94.690  103.947 1.00 97.77  ? 129 LEU A C   1 
ATOM 280  O O   . LEU A 1 55  ? 156.795 93.494  104.012 1.00 99.44  ? 129 LEU A O   1 
ATOM 281  C CB  . LEU A 1 55  ? 155.446 96.392  104.751 1.00 100.26 ? 129 LEU A CB  1 
ATOM 282  C CG  . LEU A 1 55  ? 154.851 97.234  105.880 1.00 103.29 ? 129 LEU A CG  1 
ATOM 283  C CD1 . LEU A 1 55  ? 153.590 97.945  105.415 1.00 100.59 ? 129 LEU A CD1 1 
ATOM 284  C CD2 . LEU A 1 55  ? 154.565 96.369  107.099 1.00 101.69 ? 129 LEU A CD2 1 
ATOM 285  N N   . MET A 1 56  ? 157.760 95.198  102.903 1.00 99.76  ? 130 MET A N   1 
ATOM 286  C CA  . MET A 1 56  ? 158.216 94.333  101.825 1.00 103.29 ? 130 MET A CA  1 
ATOM 287  C C   . MET A 1 56  ? 159.402 93.477  102.247 1.00 103.51 ? 130 MET A C   1 
ATOM 288  O O   . MET A 1 56  ? 159.611 92.402  101.674 1.00 104.55 ? 130 MET A O   1 
ATOM 289  C CB  . MET A 1 56  ? 158.583 95.168  100.597 1.00 103.94 ? 130 MET A CB  1 
ATOM 290  C CG  . MET A 1 56  ? 158.762 94.359  99.327  1.00 103.67 ? 130 MET A CG  1 
ATOM 291  S SD  . MET A 1 56  ? 157.210 93.614  98.797  1.00 108.90 ? 130 MET A SD  1 
ATOM 292  C CE  . MET A 1 56  ? 156.241 95.080  98.449  1.00 100.79 ? 130 MET A CE  1 
ATOM 293  N N   . GLU A 1 57  ? 160.178 93.928  103.237 1.00 102.74 ? 131 GLU A N   1 
ATOM 294  C CA  . GLU A 1 57  ? 161.288 93.121  103.731 1.00 102.74 ? 131 GLU A CA  1 
ATOM 295  C C   . GLU A 1 57  ? 160.789 91.811  104.324 1.00 103.48 ? 131 GLU A C   1 
ATOM 296  O O   . GLU A 1 57  ? 161.368 90.747  104.076 1.00 105.09 ? 131 GLU A O   1 
ATOM 297  C CB  . GLU A 1 57  ? 162.088 93.911  104.765 1.00 103.99 ? 131 GLU A CB  1 
ATOM 298  C CG  . GLU A 1 57  ? 163.312 93.185  105.292 1.00 105.78 ? 131 GLU A CG  1 
ATOM 299  C CD  . GLU A 1 57  ? 164.061 93.990  106.334 1.00 106.03 ? 131 GLU A CD  1 
ATOM 300  O OE1 . GLU A 1 57  ? 163.700 95.166  106.552 1.00 104.25 ? 131 GLU A OE1 1 
ATOM 301  O OE2 . GLU A 1 57  ? 165.013 93.448  106.935 1.00 105.48 ? 131 GLU A OE2 1 
ATOM 302  N N   . GLU A 1 58  ? 159.717 91.866  105.106 1.00 105.86 ? 132 GLU A N   1 
ATOM 303  C CA  . GLU A 1 58  ? 159.085 90.653  105.593 1.00 106.43 ? 132 GLU A CA  1 
ATOM 304  C C   . GLU A 1 58  ? 158.307 89.980  104.466 1.00 109.68 ? 132 GLU A C   1 
ATOM 305  O O   . GLU A 1 58  ? 157.887 90.618  103.497 1.00 111.97 ? 132 GLU A O   1 
ATOM 306  C CB  . GLU A 1 58  ? 158.161 90.961  106.770 1.00 106.94 ? 132 GLU A CB  1 
ATOM 307  C CG  . GLU A 1 58  ? 158.855 91.650  107.936 1.00 108.95 ? 132 GLU A CG  1 
ATOM 308  C CD  . GLU A 1 58  ? 157.902 91.999  109.062 1.00 110.51 ? 132 GLU A CD  1 
ATOM 309  O OE1 . GLU A 1 58  ? 156.703 91.665  108.955 1.00 111.68 ? 132 GLU A OE1 1 
ATOM 310  O OE2 . GLU A 1 58  ? 158.352 92.610  110.054 1.00 109.03 ? 132 GLU A OE2 1 
ATOM 311  N N   . ASN A 1 59  ? 158.116 88.668  104.604 1.00 115.68 ? 133 ASN A N   1 
ATOM 312  C CA  . ASN A 1 59  ? 157.438 87.874  103.580 1.00 114.99 ? 133 ASN A CA  1 
ATOM 313  C C   . ASN A 1 59  ? 155.926 88.111  103.630 1.00 115.35 ? 133 ASN A C   1 
ATOM 314  O O   . ASN A 1 59  ? 155.127 87.222  103.921 1.00 116.38 ? 133 ASN A O   1 
ATOM 315  C CB  . ASN A 1 59  ? 157.781 86.398  103.746 1.00 115.52 ? 133 ASN A CB  1 
ATOM 316  C CG  . ASN A 1 59  ? 157.620 85.917  105.176 1.00 118.37 ? 133 ASN A CG  1 
ATOM 317  O OD1 . ASN A 1 59  ? 157.029 86.599  106.013 1.00 118.70 ? 133 ASN A OD1 1 
ATOM 318  N ND2 . ASN A 1 59  ? 158.148 84.732  105.463 1.00 117.42 ? 133 ASN A ND2 1 
ATOM 319  N N   . MET A 1 60  ? 155.543 89.351  103.333 1.00 100.54 ? 134 MET A N   1 
ATOM 320  C CA  . MET A 1 60  ? 154.152 89.776  103.382 1.00 100.09 ? 134 MET A CA  1 
ATOM 321  C C   . MET A 1 60  ? 153.804 90.493  102.087 1.00 97.81  ? 134 MET A C   1 
ATOM 322  O O   . MET A 1 60  ? 154.496 91.436  101.692 1.00 95.82  ? 134 MET A O   1 
ATOM 323  C CB  . MET A 1 60  ? 153.903 90.694  104.584 1.00 97.48  ? 134 MET A CB  1 
ATOM 324  C CG  . MET A 1 60  ? 152.459 90.743  105.046 1.00 93.13  ? 134 MET A CG  1 
ATOM 325  S SD  . MET A 1 60  ? 152.327 91.126  106.801 1.00 100.30 ? 134 MET A SD  1 
ATOM 326  C CE  . MET A 1 60  ? 153.301 89.803  107.509 1.00 97.43  ? 134 MET A CE  1 
ATOM 327  N N   . ILE A 1 61  ? 152.733 90.045  101.431 1.00 90.05  ? 135 ILE A N   1 
ATOM 328  C CA  . ILE A 1 61  ? 152.276 90.694  100.208 1.00 87.63  ? 135 ILE A CA  1 
ATOM 329  C C   . ILE A 1 61  ? 151.707 92.062  100.551 1.00 85.79  ? 135 ILE A C   1 
ATOM 330  O O   . ILE A 1 61  ? 150.896 92.201  101.476 1.00 90.53  ? 135 ILE A O   1 
ATOM 331  C CB  . ILE A 1 61  ? 151.238 89.819  99.491  1.00 88.29  ? 135 ILE A CB  1 
ATOM 332  C CG1 . ILE A 1 61  ? 151.800 88.417  99.245  1.00 88.99  ? 135 ILE A CG1 1 
ATOM 333  C CG2 . ILE A 1 61  ? 150.811 90.463  98.181  1.00 85.61  ? 135 ILE A CG2 1 
ATOM 334  C CD1 . ILE A 1 61  ? 153.051 88.400  98.393  1.00 85.12  ? 135 ILE A CD1 1 
ATOM 335  N N   . VAL A 1 62  ? 152.131 93.081  99.812  1.00 64.33  ? 136 VAL A N   1 
ATOM 336  C CA  . VAL A 1 62  ? 151.749 94.461  100.081 1.00 62.86  ? 136 VAL A CA  1 
ATOM 337  C C   . VAL A 1 62  ? 150.805 94.928  98.985  1.00 66.97  ? 136 VAL A C   1 
ATOM 338  O O   . VAL A 1 62  ? 151.143 94.876  97.796  1.00 74.09  ? 136 VAL A O   1 
ATOM 339  C CB  . VAL A 1 62  ? 152.975 95.381  100.174 1.00 67.45  ? 136 VAL A CB  1 
ATOM 340  C CG1 . VAL A 1 62  ? 152.537 96.824  100.343 1.00 71.07  ? 136 VAL A CG1 1 
ATOM 341  C CG2 . VAL A 1 62  ? 153.865 94.953  101.326 1.00 70.19  ? 136 VAL A CG2 1 
ATOM 342  N N   . TYR A 1 63  ? 149.624 95.386  99.386  1.00 66.29  ? 137 TYR A N   1 
ATOM 343  C CA  . TYR A 1 63  ? 148.682 96.042  98.493  1.00 54.81  ? 137 TYR A CA  1 
ATOM 344  C C   . TYR A 1 63  ? 148.740 97.541  98.738  1.00 56.69  ? 137 TYR A C   1 
ATOM 345  O O   . TYR A 1 63  ? 148.749 97.987  99.889  1.00 76.05  ? 137 TYR A O   1 
ATOM 346  C CB  . TYR A 1 63  ? 147.257 95.539  98.721  1.00 66.04  ? 137 TYR A CB  1 
ATOM 347  C CG  . TYR A 1 63  ? 146.899 94.276  97.980  1.00 66.63  ? 137 TYR A CG  1 
ATOM 348  C CD1 . TYR A 1 63  ? 147.515 93.072  98.282  1.00 69.92  ? 137 TYR A CD1 1 
ATOM 349  C CD2 . TYR A 1 63  ? 145.931 94.285  96.987  1.00 64.07  ? 137 TYR A CD2 1 
ATOM 350  C CE1 . TYR A 1 63  ? 147.183 91.913  97.610  1.00 72.06  ? 137 TYR A CE1 1 
ATOM 351  C CE2 . TYR A 1 63  ? 145.591 93.134  96.311  1.00 66.53  ? 137 TYR A CE2 1 
ATOM 352  C CZ  . TYR A 1 63  ? 146.220 91.950  96.625  1.00 72.37  ? 137 TYR A CZ  1 
ATOM 353  O OH  . TYR A 1 63  ? 145.886 90.799  95.950  1.00 75.98  ? 137 TYR A OH  1 
ATOM 354  N N   . VAL A 1 64  ? 148.788 98.312  97.661  1.00 44.91  ? 138 VAL A N   1 
ATOM 355  C CA  . VAL A 1 64  ? 148.726 99.763  97.732  1.00 56.93  ? 138 VAL A CA  1 
ATOM 356  C C   . VAL A 1 64  ? 147.691 100.214 96.712  1.00 64.66  ? 138 VAL A C   1 
ATOM 357  O O   . VAL A 1 64  ? 147.435 99.523  95.721  1.00 68.89  ? 138 VAL A O   1 
ATOM 358  C CB  . VAL A 1 64  ? 150.112 100.406 97.474  1.00 67.73  ? 138 VAL A CB  1 
ATOM 359  C CG1 . VAL A 1 64  ? 150.037 101.927 97.456  1.00 69.94  ? 138 VAL A CG1 1 
ATOM 360  C CG2 . VAL A 1 64  ? 151.113 99.944  98.521  1.00 62.74  ? 138 VAL A CG2 1 
ATOM 361  N N   . GLU A 1 65  ? 147.078 101.367 96.969  1.00 74.19  ? 139 GLU A N   1 
ATOM 362  C CA  . GLU A 1 65  ? 146.036 101.872 96.085  1.00 75.51  ? 139 GLU A CA  1 
ATOM 363  C C   . GLU A 1 65  ? 146.568 102.035 94.667  1.00 76.94  ? 139 GLU A C   1 
ATOM 364  O O   . GLU A 1 65  ? 147.726 102.404 94.456  1.00 79.56  ? 139 GLU A O   1 
ATOM 365  C CB  . GLU A 1 65  ? 145.496 103.202 96.606  1.00 73.25  ? 139 GLU A CB  1 
ATOM 366  C CG  . GLU A 1 65  ? 144.164 103.607 96.003  1.00 74.30  ? 139 GLU A CG  1 
ATOM 367  C CD  . GLU A 1 65  ? 143.021 102.721 96.462  1.00 81.24  ? 139 GLU A CD  1 
ATOM 368  O OE1 . GLU A 1 65  ? 143.161 102.057 97.511  1.00 80.53  ? 139 GLU A OE1 1 
ATOM 369  O OE2 . GLU A 1 65  ? 141.982 102.686 95.770  1.00 82.42  ? 139 GLU A OE2 1 
ATOM 370  N N   . LYS A 1 66  ? 145.705 101.743 93.692  1.00 69.83  ? 140 LYS A N   1 
ATOM 371  C CA  . LYS A 1 66  ? 146.129 101.705 92.296  1.00 67.67  ? 140 LYS A CA  1 
ATOM 372  C C   . LYS A 1 66  ? 146.618 103.069 91.825  1.00 62.44  ? 140 LYS A C   1 
ATOM 373  O O   . LYS A 1 66  ? 147.618 103.165 91.106  1.00 64.08  ? 140 LYS A O   1 
ATOM 374  C CB  . LYS A 1 66  ? 144.978 101.210 91.417  1.00 67.96  ? 140 LYS A CB  1 
ATOM 375  C CG  . LYS A 1 66  ? 144.768 99.695  91.437  1.00 68.43  ? 140 LYS A CG  1 
ATOM 376  C CD  . LYS A 1 66  ? 144.136 99.220  92.739  1.00 61.04  ? 140 LYS A CD  1 
ATOM 377  C CE  . LYS A 1 66  ? 143.869 97.727  92.724  1.00 60.56  ? 140 LYS A CE  1 
ATOM 378  N NZ  . LYS A 1 66  ? 143.371 97.247  94.042  1.00 63.76  ? 140 LYS A NZ  1 
ATOM 379  N N   . LYS A 1 67  ? 145.926 104.137 92.222  1.00 72.76  ? 141 LYS A N   1 
ATOM 380  C CA  . LYS A 1 67  ? 146.320 105.479 91.814  1.00 75.88  ? 141 LYS A CA  1 
ATOM 381  C C   . LYS A 1 67  ? 147.582 105.955 92.524  1.00 73.98  ? 141 LYS A C   1 
ATOM 382  O O   . LYS A 1 67  ? 148.308 106.787 91.973  1.00 73.61  ? 141 LYS A O   1 
ATOM 383  C CB  . LYS A 1 67  ? 145.160 106.450 92.062  1.00 79.39  ? 141 LYS A CB  1 
ATOM 384  C CG  . LYS A 1 67  ? 145.352 107.861 91.510  1.00 79.71  ? 141 LYS A CG  1 
ATOM 385  C CD  . LYS A 1 67  ? 145.941 108.807 92.550  1.00 78.96  ? 141 LYS A CD  1 
ATOM 386  C CE  . LYS A 1 67  ? 146.064 110.219 92.012  1.00 77.56  ? 141 LYS A CE  1 
ATOM 387  N NZ  . LYS A 1 67  ? 146.682 111.131 93.012  1.00 76.65  ? 141 LYS A NZ  1 
ATOM 388  N N   . VAL A 1 68  ? 147.863 105.444 93.724  1.00 78.65  ? 142 VAL A N   1 
ATOM 389  C CA  . VAL A 1 68  ? 148.990 105.948 94.504  1.00 78.04  ? 142 VAL A CA  1 
ATOM 390  C C   . VAL A 1 68  ? 150.311 105.645 93.809  1.00 79.61  ? 142 VAL A C   1 
ATOM 391  O O   . VAL A 1 68  ? 151.218 106.485 93.777  1.00 82.44  ? 142 VAL A O   1 
ATOM 392  C CB  . VAL A 1 68  ? 148.951 105.363 95.927  1.00 82.94  ? 142 VAL A CB  1 
ATOM 393  C CG1 . VAL A 1 68  ? 150.246 105.661 96.667  1.00 83.67  ? 142 VAL A CG1 1 
ATOM 394  C CG2 . VAL A 1 68  ? 147.763 105.922 96.690  1.00 83.26  ? 142 VAL A CG2 1 
ATOM 395  N N   . LEU A 1 69  ? 150.439 104.453 93.232  1.00 86.81  ? 143 LEU A N   1 
ATOM 396  C CA  . LEU A 1 69  ? 151.688 104.006 92.616  1.00 88.53  ? 143 LEU A CA  1 
ATOM 397  C C   . LEU A 1 69  ? 151.965 104.680 91.277  1.00 90.75  ? 143 LEU A C   1 
ATOM 398  O O   . LEU A 1 69  ? 152.943 104.342 90.603  1.00 90.39  ? 143 LEU A O   1 
ATOM 399  C CB  . LEU A 1 69  ? 151.663 102.487 92.469  1.00 89.12  ? 143 LEU A CB  1 
ATOM 400  C CG  . LEU A 1 69  ? 150.533 101.835 91.659  1.00 89.00  ? 143 LEU A CG  1 
ATOM 401  C CD1 . LEU A 1 69  ? 150.841 101.783 90.165  1.00 89.67  ? 143 LEU A CD1 1 
ATOM 402  C CD2 . LEU A 1 69  ? 150.217 100.444 92.192  1.00 85.61  ? 143 LEU A CD2 1 
ATOM 403  N N   . GLU A 1 70  ? 151.133 105.640 90.861  1.00 91.75  ? 144 GLU A N   1 
ATOM 404  C CA  . GLU A 1 70  ? 151.344 106.308 89.583  1.00 86.65  ? 144 GLU A CA  1 
ATOM 405  C C   . GLU A 1 70  ? 151.330 107.828 89.695  1.00 86.36  ? 144 GLU A C   1 
ATOM 406  O O   . GLU A 1 70  ? 151.177 108.505 88.670  1.00 88.33  ? 144 GLU A O   1 
ATOM 407  C CB  . GLU A 1 70  ? 150.298 105.853 88.556  1.00 88.65  ? 144 GLU A CB  1 
ATOM 408  C CG  . GLU A 1 70  ? 148.870 106.238 88.896  1.00 93.09  ? 144 GLU A CG  1 
ATOM 409  C CD  . GLU A 1 70  ? 147.874 105.752 87.861  1.00 94.74  ? 144 GLU A CD  1 
ATOM 410  O OE1 . GLU A 1 70  ? 148.301 105.110 86.879  1.00 91.68  ? 144 GLU A OE1 1 
ATOM 411  O OE2 . GLU A 1 70  ? 146.664 106.012 88.030  1.00 96.80  ? 144 GLU A OE2 1 
ATOM 412  N N   . ASP A 1 71  ? 151.476 108.386 90.892  1.00 97.09  ? 145 ASP A N   1 
ATOM 413  C CA  . ASP A 1 71  ? 151.616 109.826 91.025  1.00 98.29  ? 145 ASP A CA  1 
ATOM 414  C C   . ASP A 1 71  ? 152.981 110.275 90.506  1.00 99.36  ? 145 ASP A C   1 
ATOM 415  O O   . ASP A 1 71  ? 153.950 109.512 90.544  1.00 100.62 ? 145 ASP A O   1 
ATOM 416  C CB  . ASP A 1 71  ? 151.449 110.253 92.481  1.00 98.06  ? 145 ASP A CB  1 
ATOM 417  C CG  . ASP A 1 71  ? 150.114 109.836 93.060  1.00 99.12  ? 145 ASP A CG  1 
ATOM 418  O OD1 . ASP A 1 71  ? 149.272 109.318 92.299  1.00 100.20 ? 145 ASP A OD1 1 
ATOM 419  O OD2 . ASP A 1 71  ? 149.906 110.030 94.275  1.00 99.64  ? 145 ASP A OD2 1 
ATOM 420  N N   . PRO A 1 72  ? 153.080 111.508 90.003  1.00 109.54 ? 146 PRO A N   1 
ATOM 421  C CA  . PRO A 1 72  ? 154.384 111.993 89.523  1.00 109.33 ? 146 PRO A CA  1 
ATOM 422  C C   . PRO A 1 72  ? 155.450 112.028 90.602  1.00 106.88 ? 146 PRO A C   1 
ATOM 423  O O   . PRO A 1 72  ? 156.633 111.833 90.296  1.00 107.95 ? 146 PRO A O   1 
ATOM 424  C CB  . PRO A 1 72  ? 154.063 113.400 88.997  1.00 110.62 ? 146 PRO A CB  1 
ATOM 425  C CG  . PRO A 1 72  ? 152.791 113.787 89.686  1.00 110.47 ? 146 PRO A CG  1 
ATOM 426  C CD  . PRO A 1 72  ? 152.019 112.513 89.827  1.00 109.33 ? 146 PRO A CD  1 
ATOM 427  N N   . ALA A 1 73  ? 155.069 112.275 91.857  1.00 99.71  ? 147 ALA A N   1 
ATOM 428  C CA  . ALA A 1 73  ? 156.052 112.312 92.934  1.00 102.04 ? 147 ALA A CA  1 
ATOM 429  C C   . ALA A 1 73  ? 156.691 110.946 93.150  1.00 103.08 ? 147 ALA A C   1 
ATOM 430  O O   . ALA A 1 73  ? 157.903 110.849 93.376  1.00 100.20 ? 147 ALA A O   1 
ATOM 431  C CB  . ALA A 1 73  ? 155.400 112.810 94.223  1.00 102.99 ? 147 ALA A CB  1 
ATOM 432  N N   . ILE A 1 74  ? 155.894 109.878 93.089  1.00 106.92 ? 148 ILE A N   1 
ATOM 433  C CA  . ILE A 1 74  ? 156.439 108.546 93.328  1.00 105.16 ? 148 ILE A CA  1 
ATOM 434  C C   . ILE A 1 74  ? 157.092 107.982 92.069  1.00 105.76 ? 148 ILE A C   1 
ATOM 435  O O   . ILE A 1 74  ? 157.987 107.135 92.158  1.00 107.13 ? 148 ILE A O   1 
ATOM 436  C CB  . ILE A 1 74  ? 155.344 107.609 93.869  1.00 104.70 ? 148 ILE A CB  1 
ATOM 437  C CG1 . ILE A 1 74  ? 155.971 106.434 94.624  1.00 106.64 ? 148 ILE A CG1 1 
ATOM 438  C CG2 . ILE A 1 74  ? 154.443 107.108 92.747  1.00 101.18 ? 148 ILE A CG2 1 
ATOM 439  C CD1 . ILE A 1 74  ? 154.958 105.471 95.204  1.00 107.08 ? 148 ILE A CD1 1 
ATOM 440  N N   . ALA A 1 75  ? 156.667 108.432 90.887  1.00 111.20 ? 149 ALA A N   1 
ATOM 441  C CA  . ALA A 1 75  ? 157.276 107.959 89.651  1.00 111.74 ? 149 ALA A CA  1 
ATOM 442  C C   . ALA A 1 75  ? 158.624 108.616 89.385  1.00 113.30 ? 149 ALA A C   1 
ATOM 443  O O   . ALA A 1 75  ? 159.525 107.969 88.839  1.00 111.70 ? 149 ALA A O   1 
ATOM 444  C CB  . ALA A 1 75  ? 156.333 108.203 88.472  1.00 112.85 ? 149 ALA A CB  1 
ATOM 445  N N   . SER A 1 76  ? 158.778 109.889 89.758  1.00 120.78 ? 150 SER A N   1 
ATOM 446  C CA  . SER A 1 76  ? 160.015 110.607 89.467  1.00 119.59 ? 150 SER A CA  1 
ATOM 447  C C   . SER A 1 76  ? 161.202 110.001 90.205  1.00 118.98 ? 150 SER A C   1 
ATOM 448  O O   . SER A 1 76  ? 162.294 109.876 89.638  1.00 117.94 ? 150 SER A O   1 
ATOM 449  C CB  . SER A 1 76  ? 159.860 112.085 89.827  1.00 119.15 ? 150 SER A CB  1 
ATOM 450  O OG  . SER A 1 76  ? 158.793 112.676 89.106  1.00 118.77 ? 150 SER A OG  1 
ATOM 451  N N   . ASP A 1 77  ? 161.012 109.620 91.465  1.00 122.87 ? 151 ASP A N   1 
ATOM 452  C CA  . ASP A 1 77  ? 162.095 109.068 92.276  1.00 124.67 ? 151 ASP A CA  1 
ATOM 453  C C   . ASP A 1 77  ? 162.410 107.660 91.789  1.00 124.46 ? 151 ASP A C   1 
ATOM 454  O O   . ASP A 1 77  ? 161.703 106.703 92.112  1.00 124.52 ? 151 ASP A O   1 
ATOM 455  C CB  . ASP A 1 77  ? 161.708 109.069 93.751  1.00 122.78 ? 151 ASP A CB  1 
ATOM 456  C CG  . ASP A 1 77  ? 162.863 108.689 94.660  1.00 122.28 ? 151 ASP A CG  1 
ATOM 457  O OD1 . ASP A 1 77  ? 164.005 108.582 94.166  1.00 120.96 ? 151 ASP A OD1 1 
ATOM 458  O OD2 . ASP A 1 77  ? 162.626 108.497 95.871  1.00 122.62 ? 151 ASP A OD2 1 
ATOM 459  N N   . GLU A 1 78  ? 163.479 107.528 91.001  1.00 121.51 ? 152 GLU A N   1 
ATOM 460  C CA  . GLU A 1 78  ? 163.894 106.221 90.509  1.00 121.36 ? 152 GLU A CA  1 
ATOM 461  C C   . GLU A 1 78  ? 164.493 105.349 91.603  1.00 119.12 ? 152 GLU A C   1 
ATOM 462  O O   . GLU A 1 78  ? 164.576 104.129 91.427  1.00 118.96 ? 152 GLU A O   1 
ATOM 463  C CB  . GLU A 1 78  ? 164.905 106.374 89.368  1.00 121.63 ? 152 GLU A CB  1 
ATOM 464  C CG  . GLU A 1 78  ? 166.198 107.081 89.753  1.00 120.63 ? 152 GLU A CG  1 
ATOM 465  C CD  . GLU A 1 78  ? 166.070 108.592 89.751  1.00 121.27 ? 152 GLU A CD  1 
ATOM 466  O OE1 . GLU A 1 78  ? 165.019 109.101 89.308  1.00 122.28 ? 152 GLU A OE1 1 
ATOM 467  O OE2 . GLU A 1 78  ? 167.020 109.272 90.193  1.00 120.38 ? 152 GLU A OE2 1 
ATOM 468  N N   . SER A 1 79  ? 164.916 105.945 92.720  1.00 105.78 ? 153 SER A N   1 
ATOM 469  C CA  . SER A 1 79  ? 165.471 105.156 93.814  1.00 106.12 ? 153 SER A CA  1 
ATOM 470  C C   . SER A 1 79  ? 164.430 104.206 94.390  1.00 107.79 ? 153 SER A C   1 
ATOM 471  O O   . SER A 1 79  ? 164.733 103.045 94.688  1.00 106.53 ? 153 SER A O   1 
ATOM 472  C CB  . SER A 1 79  ? 166.016 106.080 94.902  1.00 106.10 ? 153 SER A CB  1 
ATOM 473  O OG  . SER A 1 79  ? 166.551 105.333 95.980  1.00 108.05 ? 153 SER A OG  1 
ATOM 474  N N   . PHE A 1 80  ? 163.193 104.677 94.546  1.00 107.09 ? 154 PHE A N   1 
ATOM 475  C CA  . PHE A 1 80  ? 162.124 103.855 95.096  1.00 106.62 ? 154 PHE A CA  1 
ATOM 476  C C   . PHE A 1 80  ? 161.566 102.854 94.094  1.00 104.67 ? 154 PHE A C   1 
ATOM 477  O O   . PHE A 1 80  ? 160.755 102.005 94.479  1.00 104.58 ? 154 PHE A O   1 
ATOM 478  C CB  . PHE A 1 80  ? 160.994 104.744 95.620  1.00 103.58 ? 154 PHE A CB  1 
ATOM 479  C CG  . PHE A 1 80  ? 160.037 104.030 96.530  1.00 105.44 ? 154 PHE A CG  1 
ATOM 480  C CD1 . PHE A 1 80  ? 160.442 103.598 97.781  1.00 105.98 ? 154 PHE A CD1 1 
ATOM 481  C CD2 . PHE A 1 80  ? 158.730 103.798 96.137  1.00 105.79 ? 154 PHE A CD2 1 
ATOM 482  C CE1 . PHE A 1 80  ? 159.564 102.940 98.620  1.00 107.46 ? 154 PHE A CE1 1 
ATOM 483  C CE2 . PHE A 1 80  ? 157.846 103.142 96.972  1.00 104.09 ? 154 PHE A CE2 1 
ATOM 484  C CZ  . PHE A 1 80  ? 158.264 102.714 98.216  1.00 105.59 ? 154 PHE A CZ  1 
ATOM 485  N N   . GLY A 1 81  ? 161.984 102.920 92.831  1.00 96.74  ? 155 GLY A N   1 
ATOM 486  C CA  . GLY A 1 81  ? 161.477 102.001 91.829  1.00 97.81  ? 155 GLY A CA  1 
ATOM 487  C C   . GLY A 1 81  ? 161.850 100.553 92.057  1.00 96.99  ? 155 GLY A C   1 
ATOM 488  O O   . GLY A 1 81  ? 161.291 99.678  91.387  1.00 98.54  ? 155 GLY A O   1 
ATOM 489  N N   . ALA A 1 82  ? 162.779 100.280 92.977  1.00 87.07  ? 156 ALA A N   1 
ATOM 490  C CA  . ALA A 1 82  ? 163.178 98.902  93.239  1.00 89.87  ? 156 ALA A CA  1 
ATOM 491  C C   . ALA A 1 82  ? 162.014 98.080  93.775  1.00 91.59  ? 156 ALA A C   1 
ATOM 492  O O   . ALA A 1 82  ? 161.810 96.933  93.359  1.00 94.18  ? 156 ALA A O   1 
ATOM 493  C CB  . ALA A 1 82  ? 164.351 98.873  94.218  1.00 91.38  ? 156 ALA A CB  1 
ATOM 494  N N   . VAL A 1 83  ? 161.233 98.650  94.698  1.00 95.32  ? 157 VAL A N   1 
ATOM 495  C CA  . VAL A 1 83  ? 160.129 97.918  95.313  1.00 97.56  ? 157 VAL A CA  1 
ATOM 496  C C   . VAL A 1 83  ? 158.781 98.230  94.682  1.00 94.63  ? 157 VAL A C   1 
ATOM 497  O O   . VAL A 1 83  ? 157.792 97.550  94.998  1.00 94.39  ? 157 VAL A O   1 
ATOM 498  C CB  . VAL A 1 83  ? 160.055 98.204  96.825  1.00 99.16  ? 157 VAL A CB  1 
ATOM 499  C CG1 . VAL A 1 83  ? 161.280 97.642  97.530  1.00 96.95  ? 157 VAL A CG1 1 
ATOM 500  C CG2 . VAL A 1 83  ? 159.928 99.699  97.074  1.00 98.12  ? 157 VAL A CG2 1 
ATOM 501  N N   . LYS A 1 84  ? 158.706 99.233  93.805  1.00 90.98  ? 158 LYS A N   1 
ATOM 502  C CA  . LYS A 1 84  ? 157.427 99.599  93.203  1.00 92.76  ? 158 LYS A CA  1 
ATOM 503  C C   . LYS A 1 84  ? 156.832 98.442  92.412  1.00 93.47  ? 158 LYS A C   1 
ATOM 504  O O   . LYS A 1 84  ? 155.607 98.287  92.351  1.00 95.53  ? 158 LYS A O   1 
ATOM 505  C CB  . LYS A 1 84  ? 157.600 100.825 92.307  1.00 95.36  ? 158 LYS A CB  1 
ATOM 506  C CG  . LYS A 1 84  ? 157.808 102.122 93.067  1.00 96.29  ? 158 LYS A CG  1 
ATOM 507  C CD  . LYS A 1 84  ? 157.871 103.313 92.125  1.00 96.00  ? 158 LYS A CD  1 
ATOM 508  C CE  . LYS A 1 84  ? 156.558 103.500 91.381  1.00 95.69  ? 158 LYS A CE  1 
ATOM 509  N NZ  . LYS A 1 84  ? 156.588 104.697 90.495  1.00 96.02  ? 158 LYS A NZ  1 
ATOM 510  N N   . LYS A 1 85  ? 157.682 97.617  91.802  1.00 100.92 ? 159 LYS A N   1 
ATOM 511  C CA  . LYS A 1 85  ? 157.199 96.495  91.008  1.00 103.59 ? 159 LYS A CA  1 
ATOM 512  C C   . LYS A 1 85  ? 156.611 95.377  91.858  1.00 101.87 ? 159 LYS A C   1 
ATOM 513  O O   . LYS A 1 85  ? 156.003 94.457  91.301  1.00 102.47 ? 159 LYS A O   1 
ATOM 514  C CB  . LYS A 1 85  ? 158.331 95.940  90.142  1.00 103.33 ? 159 LYS A CB  1 
ATOM 515  C CG  . LYS A 1 85  ? 158.805 96.892  89.055  1.00 102.70 ? 159 LYS A CG  1 
ATOM 516  C CD  . LYS A 1 85  ? 159.945 96.289  88.251  1.00 102.49 ? 159 LYS A CD  1 
ATOM 517  C CE  . LYS A 1 85  ? 160.402 97.229  87.148  1.00 102.34 ? 159 LYS A CE  1 
ATOM 518  N NZ  . LYS A 1 85  ? 161.535 96.661  86.367  1.00 101.74 ? 159 LYS A NZ  1 
ATOM 519  N N   . LYS A 1 86  ? 156.772 95.430  93.177  1.00 88.55  ? 160 LYS A N   1 
ATOM 520  C CA  . LYS A 1 86  ? 156.319 94.360  94.054  1.00 91.04  ? 160 LYS A CA  1 
ATOM 521  C C   . LYS A 1 86  ? 154.978 94.656  94.717  1.00 95.40  ? 160 LYS A C   1 
ATOM 522  O O   . LYS A 1 86  ? 154.594 93.939  95.648  1.00 96.78  ? 160 LYS A O   1 
ATOM 523  C CB  . LYS A 1 86  ? 157.381 94.077  95.120  1.00 91.13  ? 160 LYS A CB  1 
ATOM 524  C CG  . LYS A 1 86  ? 158.752 93.762  94.541  1.00 90.69  ? 160 LYS A CG  1 
ATOM 525  C CD  . LYS A 1 86  ? 159.755 93.404  95.623  1.00 91.17  ? 160 LYS A CD  1 
ATOM 526  C CE  . LYS A 1 86  ? 159.352 92.129  96.344  1.00 92.17  ? 160 LYS A CE  1 
ATOM 527  N NZ  . LYS A 1 86  ? 160.306 91.780  97.433  1.00 91.18  ? 160 LYS A NZ  1 
ATOM 528  N N   . PHE A 1 87  ? 154.261 95.682  94.266  1.00 74.95  ? 161 PHE A N   1 
ATOM 529  C CA  . PHE A 1 87  ? 152.942 95.983  94.800  1.00 59.32  ? 161 PHE A CA  1 
ATOM 530  C C   . PHE A 1 87  ? 151.899 95.060  94.175  1.00 62.10  ? 161 PHE A C   1 
ATOM 531  O O   . PHE A 1 87  ? 152.215 94.084  93.491  1.00 70.98  ? 161 PHE A O   1 
ATOM 532  C CB  . PHE A 1 87  ? 152.583 97.443  94.542  1.00 59.17  ? 161 PHE A CB  1 
ATOM 533  C CG  . PHE A 1 87  ? 153.405 98.418  95.324  1.00 67.78  ? 161 PHE A CG  1 
ATOM 534  C CD1 . PHE A 1 87  ? 153.996 98.045  96.518  1.00 74.57  ? 161 PHE A CD1 1 
ATOM 535  C CD2 . PHE A 1 87  ? 153.580 99.713  94.873  1.00 69.49  ? 161 PHE A CD2 1 
ATOM 536  C CE1 . PHE A 1 87  ? 154.751 98.944  97.244  1.00 73.94  ? 161 PHE A CE1 1 
ATOM 537  C CE2 . PHE A 1 87  ? 154.333 100.617 95.594  1.00 69.93  ? 161 PHE A CE2 1 
ATOM 538  C CZ  . PHE A 1 87  ? 154.919 100.232 96.781  1.00 71.55  ? 161 PHE A CZ  1 
ATOM 539  N N   . THR A 1 88  ? 150.632 95.376  94.418  1.00 55.32  ? 162 THR A N   1 
ATOM 540  C CA  . THR A 1 88  ? 149.535 94.624  93.822  1.00 60.01  ? 162 THR A CA  1 
ATOM 541  C C   . THR A 1 88  ? 148.295 95.496  93.661  1.00 60.19  ? 162 THR A C   1 
ATOM 542  O O   . THR A 1 88  ? 148.245 96.371  92.795  1.00 57.60  ? 162 THR A O   1 
ATOM 543  C CB  . THR A 1 88  ? 149.203 93.385  94.674  1.00 61.22  ? 162 THR A CB  1 
ATOM 544  O OG1 . THR A 1 88  ? 150.347 92.526  94.737  1.00 62.70  ? 162 THR A OG1 1 
ATOM 545  C CG2 . THR A 1 88  ? 148.157 92.525  93.980  1.00 57.12  ? 162 THR A CG2 1 
ATOM 546  N N   . SER A 1 98  ? 140.047 94.239  98.372  1.00 78.67  ? 172 SER A N   1 
ATOM 547  C CA  . SER A 1 98  ? 138.642 93.941  98.127  1.00 78.46  ? 172 SER A CA  1 
ATOM 548  C C   . SER A 1 98  ? 138.135 92.868  99.085  1.00 78.33  ? 172 SER A C   1 
ATOM 549  O O   . SER A 1 98  ? 137.293 93.134  99.941  1.00 76.69  ? 172 SER A O   1 
ATOM 550  C CB  . SER A 1 98  ? 138.437 93.507  96.684  1.00 76.12  ? 172 SER A CB  1 
ATOM 551  N N   . ASN A 1 99  ? 138.656 91.648  98.936  1.00 81.44  ? 173 ASN A N   1 
ATOM 552  C CA  . ASN A 1 99  ? 138.250 90.544  99.796  1.00 82.96  ? 173 ASN A CA  1 
ATOM 553  C C   . ASN A 1 99  ? 139.427 89.694  100.258 1.00 80.07  ? 173 ASN A C   1 
ATOM 554  O O   . ASN A 1 99  ? 139.207 88.656  100.895 1.00 76.92  ? 173 ASN A O   1 
ATOM 555  C CB  . ASN A 1 99  ? 137.219 89.667  99.084  1.00 30.00  ? 173 ASN A CB  1 
ATOM 556  C CG  . ASN A 1 99  ? 135.872 90.348  98.942  1.00 30.00  ? 173 ASN A CG  1 
ATOM 557  O OD1 . ASN A 1 99  ? 135.111 90.449  99.904  1.00 30.00  ? 173 ASN A OD1 1 
ATOM 558  N ND2 . ASN A 1 99  ? 135.571 90.820  97.738  1.00 30.00  ? 173 ASN A ND2 1 
ATOM 559  N N   . GLN A 1 100 ? 140.662 90.094  99.960  1.00 85.72  ? 174 GLN A N   1 
ATOM 560  C CA  . GLN A 1 100 ? 141.844 89.362  100.388 1.00 91.40  ? 174 GLN A CA  1 
ATOM 561  C C   . GLN A 1 100 ? 142.757 90.182  101.290 1.00 95.22  ? 174 GLN A C   1 
ATOM 562  O O   . GLN A 1 100 ? 143.845 89.712  101.637 1.00 96.21  ? 174 GLN A O   1 
ATOM 563  C CB  . GLN A 1 100 ? 142.632 88.861  99.170  1.00 91.44  ? 174 GLN A CB  1 
ATOM 564  C CG  . GLN A 1 100 ? 143.277 89.955  98.328  1.00 92.59  ? 174 GLN A CG  1 
ATOM 565  C CD  . GLN A 1 100 ? 142.310 90.600  97.352  1.00 94.15  ? 174 GLN A CD  1 
ATOM 566  O OE1 . GLN A 1 100 ? 141.098 90.397  97.431  1.00 94.61  ? 174 GLN A OE1 1 
ATOM 567  N NE2 . GLN A 1 100 ? 142.845 91.377  96.418  1.00 91.67  ? 174 GLN A NE2 1 
ATOM 568  N N   . ILE A 1 101 ? 142.348 91.387  101.675 1.00 84.59  ? 175 ILE A N   1 
ATOM 569  C CA  . ILE A 1 101 ? 143.137 92.211  102.583 1.00 81.73  ? 175 ILE A CA  1 
ATOM 570  C C   . ILE A 1 101 ? 143.018 91.651  103.993 1.00 77.01  ? 175 ILE A C   1 
ATOM 571  O O   . ILE A 1 101 ? 141.913 91.375  104.474 1.00 80.09  ? 175 ILE A O   1 
ATOM 572  C CB  . ILE A 1 101 ? 142.678 93.677  102.528 1.00 80.49  ? 175 ILE A CB  1 
ATOM 573  C CG1 . ILE A 1 101 ? 142.828 94.229  101.110 1.00 79.13  ? 175 ILE A CG1 1 
ATOM 574  C CG2 . ILE A 1 101 ? 143.461 94.520  103.523 1.00 80.81  ? 175 ILE A CG2 1 
ATOM 575  C CD1 . ILE A 1 101 ? 144.247 94.208  100.598 1.00 76.87  ? 175 ILE A CD1 1 
ATOM 576  N N   . ASP A 1 102 ? 144.157 91.477  104.659 1.00 66.29  ? 176 ASP A N   1 
ATOM 577  C CA  . ASP A 1 102 ? 144.179 90.923  106.005 1.00 71.14  ? 176 ASP A CA  1 
ATOM 578  C C   . ASP A 1 102 ? 144.457 91.958  107.082 1.00 73.13  ? 176 ASP A C   1 
ATOM 579  O O   . ASP A 1 102 ? 144.144 91.712  108.251 1.00 78.89  ? 176 ASP A O   1 
ATOM 580  C CB  . ASP A 1 102 ? 145.228 89.811  106.103 1.00 76.91  ? 176 ASP A CB  1 
ATOM 581  C CG  . ASP A 1 102 ? 144.895 88.618  105.232 1.00 79.95  ? 176 ASP A CG  1 
ATOM 582  O OD1 . ASP A 1 102 ? 143.693 88.368  105.002 1.00 78.87  ? 176 ASP A OD1 1 
ATOM 583  O OD2 . ASP A 1 102 ? 145.833 87.928  104.782 1.00 81.52  ? 176 ASP A OD2 1 
ATOM 584  N N   . PHE A 1 103 ? 145.029 93.104  106.725 1.00 59.38  ? 177 PHE A N   1 
ATOM 585  C CA  . PHE A 1 103 ? 145.383 94.112  107.712 1.00 59.60  ? 177 PHE A CA  1 
ATOM 586  C C   . PHE A 1 103 ? 145.638 95.428  106.994 1.00 64.64  ? 177 PHE A C   1 
ATOM 587  O O   . PHE A 1 103 ? 146.216 95.451  105.904 1.00 73.34  ? 177 PHE A O   1 
ATOM 588  C CB  . PHE A 1 103 ? 146.607 93.680  108.525 1.00 63.52  ? 177 PHE A CB  1 
ATOM 589  C CG  . PHE A 1 103 ? 147.111 94.725  109.471 1.00 65.47  ? 177 PHE A CG  1 
ATOM 590  C CD1 . PHE A 1 103 ? 146.310 95.189  110.501 1.00 70.08  ? 177 PHE A CD1 1 
ATOM 591  C CD2 . PHE A 1 103 ? 148.394 95.226  109.348 1.00 66.48  ? 177 PHE A CD2 1 
ATOM 592  C CE1 . PHE A 1 103 ? 146.774 96.147  111.379 1.00 73.10  ? 177 PHE A CE1 1 
ATOM 593  C CE2 . PHE A 1 103 ? 148.864 96.180  110.223 1.00 70.36  ? 177 PHE A CE2 1 
ATOM 594  C CZ  . PHE A 1 103 ? 148.052 96.644  111.240 1.00 75.04  ? 177 PHE A CZ  1 
ATOM 595  N N   . ILE A 1 104 ? 145.199 96.521  107.614 1.00 58.88  ? 178 ILE A N   1 
ATOM 596  C CA  . ILE A 1 104 ? 145.211 97.842  106.998 1.00 57.03  ? 178 ILE A CA  1 
ATOM 597  C C   . ILE A 1 104 ? 146.086 98.770  107.827 1.00 59.57  ? 178 ILE A C   1 
ATOM 598  O O   . ILE A 1 104 ? 145.947 98.832  109.054 1.00 66.53  ? 178 ILE A O   1 
ATOM 599  C CB  . ILE A 1 104 ? 143.788 98.415  106.864 1.00 51.57  ? 178 ILE A CB  1 
ATOM 600  C CG1 . ILE A 1 104 ? 142.933 97.518  105.972 1.00 56.02  ? 178 ILE A CG1 1 
ATOM 601  C CG2 . ILE A 1 104 ? 143.827 99.825  106.313 1.00 56.80  ? 178 ILE A CG2 1 
ATOM 602  C CD1 . ILE A 1 104 ? 141.522 98.023  105.783 1.00 60.36  ? 178 ILE A CD1 1 
ATOM 603  N N   . ILE A 1 105 ? 146.988 99.483  107.157 1.00 56.47  ? 179 ILE A N   1 
ATOM 604  C CA  . ILE A 1 105 ? 147.795 100.533 107.766 1.00 49.10  ? 179 ILE A CA  1 
ATOM 605  C C   . ILE A 1 105 ? 147.438 101.846 107.087 1.00 54.76  ? 179 ILE A C   1 
ATOM 606  O O   . ILE A 1 105 ? 147.472 101.940 105.855 1.00 68.34  ? 179 ILE A O   1 
ATOM 607  C CB  . ILE A 1 105 ? 149.301 100.248 107.638 1.00 61.12  ? 179 ILE A CB  1 
ATOM 608  C CG1 . ILE A 1 105 ? 149.669 98.972  108.391 1.00 67.20  ? 179 ILE A CG1 1 
ATOM 609  C CG2 . ILE A 1 105 ? 150.104 101.423 108.159 1.00 62.93  ? 179 ILE A CG2 1 
ATOM 610  C CD1 . ILE A 1 105 ? 151.139 98.622  108.319 1.00 68.21  ? 179 ILE A CD1 1 
ATOM 611  N N   . CYS A 1 106 ? 147.098 102.852 107.886 1.00 58.89  ? 180 CYS A N   1 
ATOM 612  C CA  . CYS A 1 106 ? 146.640 104.136 107.377 1.00 60.14  ? 180 CYS A CA  1 
ATOM 613  C C   . CYS A 1 106 ? 147.582 105.237 107.835 1.00 65.47  ? 180 CYS A C   1 
ATOM 614  O O   . CYS A 1 106 ? 148.001 105.259 108.996 1.00 71.12  ? 180 CYS A O   1 
ATOM 615  C CB  . CYS A 1 106 ? 145.215 104.431 107.847 1.00 67.43  ? 180 CYS A CB  1 
ATOM 616  S SG  . CYS A 1 106 ? 143.937 103.501 106.977 1.00 83.79  ? 180 CYS A SG  1 
ATOM 617  N N   . LEU A 1 107 ? 147.912 106.143 106.921 1.00 87.23  ? 181 LEU A N   1 
ATOM 618  C CA  . LEU A 1 107 ? 148.726 107.314 107.216 1.00 89.46  ? 181 LEU A CA  1 
ATOM 619  C C   . LEU A 1 107 ? 147.865 108.561 107.075 1.00 91.06  ? 181 LEU A C   1 
ATOM 620  O O   . LEU A 1 107 ? 147.241 108.774 106.029 1.00 90.71  ? 181 LEU A O   1 
ATOM 621  C CB  . LEU A 1 107 ? 149.934 107.390 106.281 1.00 88.66  ? 181 LEU A CB  1 
ATOM 622  C CG  . LEU A 1 107 ? 150.908 106.212 106.341 1.00 88.18  ? 181 LEU A CG  1 
ATOM 623  C CD1 . LEU A 1 107 ? 152.049 106.408 105.357 1.00 85.58  ? 181 LEU A CD1 1 
ATOM 624  C CD2 . LEU A 1 107 ? 151.436 106.025 107.754 1.00 88.19  ? 181 LEU A CD2 1 
ATOM 625  N N   . GLY A 1 108 ? 147.831 109.379 108.123 1.00 97.33  ? 182 GLY A N   1 
ATOM 626  C CA  . GLY A 1 108 ? 147.005 110.571 108.125 1.00 96.12  ? 182 GLY A CA  1 
ATOM 627  C C   . GLY A 1 108 ? 146.063 110.619 109.311 1.00 97.04  ? 182 GLY A C   1 
ATOM 628  O O   . GLY A 1 108 ? 145.840 109.599 109.968 1.00 97.37  ? 182 GLY A O   1 
ATOM 629  N N   . GLY A 1 109 ? 145.500 111.792 109.593 1.00 101.05 ? 183 GLY A N   1 
ATOM 630  C CA  . GLY A 1 109 ? 144.670 111.959 110.772 1.00 102.33 ? 183 GLY A CA  1 
ATOM 631  C C   . GLY A 1 109 ? 143.187 112.124 110.506 1.00 103.62 ? 183 GLY A C   1 
ATOM 632  O O   . GLY A 1 109 ? 142.749 113.170 110.018 1.00 104.39 ? 183 GLY A O   1 
ATOM 633  N N   . ASP A 1 110 ? 142.411 111.080 110.810 1.00 98.58  ? 184 ASP A N   1 
ATOM 634  C CA  . ASP A 1 110 ? 140.950 111.118 110.803 1.00 96.60  ? 184 ASP A CA  1 
ATOM 635  C C   . ASP A 1 110 ? 140.360 111.368 109.420 1.00 96.26  ? 184 ASP A C   1 
ATOM 636  O O   . ASP A 1 110 ? 139.136 111.449 109.272 1.00 98.92  ? 184 ASP A O   1 
ATOM 637  C CB  . ASP A 1 110 ? 140.434 112.178 111.782 1.00 96.77  ? 184 ASP A CB  1 
ATOM 638  C CG  . ASP A 1 110 ? 140.755 111.846 113.224 1.00 97.33  ? 184 ASP A CG  1 
ATOM 639  O OD1 . ASP A 1 110 ? 141.356 110.780 113.472 1.00 94.83  ? 184 ASP A OD1 1 
ATOM 640  O OD2 . ASP A 1 110 ? 140.399 112.650 114.112 1.00 98.70  ? 184 ASP A OD2 1 
ATOM 641  N N   . GLY A 1 111 ? 141.207 111.493 108.404 1.00 76.33  ? 185 GLY A N   1 
ATOM 642  C CA  . GLY A 1 111 ? 140.719 111.684 107.054 1.00 70.79  ? 185 GLY A CA  1 
ATOM 643  C C   . GLY A 1 111 ? 140.954 110.462 106.197 1.00 70.26  ? 185 GLY A C   1 
ATOM 644  O O   . GLY A 1 111 ? 140.385 110.331 105.110 1.00 70.47  ? 185 GLY A O   1 
ATOM 645  N N   . THR A 1 112 ? 141.793 109.554 106.689 1.00 70.06  ? 186 THR A N   1 
ATOM 646  C CA  . THR A 1 112 ? 142.153 108.352 105.952 1.00 71.37  ? 186 THR A CA  1 
ATOM 647  C C   . THR A 1 112 ? 141.302 107.155 106.355 1.00 70.84  ? 186 THR A C   1 
ATOM 648  O O   . THR A 1 112 ? 140.921 106.350 105.498 1.00 70.88  ? 186 THR A O   1 
ATOM 649  C CB  . THR A 1 112 ? 143.636 108.036 106.160 1.00 70.46  ? 186 THR A CB  1 
ATOM 650  O OG1 . THR A 1 112 ? 144.426 109.146 105.718 1.00 72.77  ? 186 THR A OG1 1 
ATOM 651  C CG2 . THR A 1 112 ? 144.038 106.804 105.368 1.00 70.60  ? 186 THR A CG2 1 
ATOM 652  N N   . LEU A 1 113 ? 140.988 107.026 107.647 1.00 72.52  ? 187 LEU A N   1 
ATOM 653  C CA  . LEU A 1 113 ? 140.175 105.902 108.098 1.00 71.69  ? 187 LEU A CA  1 
ATOM 654  C C   . LEU A 1 113 ? 138.771 105.953 107.507 1.00 73.95  ? 187 LEU A C   1 
ATOM 655  O O   . LEU A 1 113 ? 138.149 104.904 107.303 1.00 74.54  ? 187 LEU A O   1 
ATOM 656  C CB  . LEU A 1 113 ? 140.118 105.874 109.626 1.00 61.84  ? 187 LEU A CB  1 
ATOM 657  C CG  . LEU A 1 113 ? 139.389 104.685 110.256 1.00 64.73  ? 187 LEU A CG  1 
ATOM 658  C CD1 . LEU A 1 113 ? 139.871 103.379 109.652 1.00 66.83  ? 187 LEU A CD1 1 
ATOM 659  C CD2 . LEU A 1 113 ? 139.576 104.672 111.762 1.00 71.43  ? 187 LEU A CD2 1 
ATOM 660  N N   . LEU A 1 114 ? 138.259 107.153 107.225 1.00 69.16  ? 188 LEU A N   1 
ATOM 661  C CA  . LEU A 1 114 ? 136.993 107.260 106.509 1.00 64.55  ? 188 LEU A CA  1 
ATOM 662  C C   . LEU A 1 114 ? 137.100 106.660 105.115 1.00 63.44  ? 188 LEU A C   1 
ATOM 663  O O   . LEU A 1 114 ? 136.194 105.951 104.664 1.00 64.55  ? 188 LEU A O   1 
ATOM 664  C CB  . LEU A 1 114 ? 136.553 108.720 106.434 1.00 65.53  ? 188 LEU A CB  1 
ATOM 665  C CG  . LEU A 1 114 ? 135.984 109.296 107.727 1.00 64.79  ? 188 LEU A CG  1 
ATOM 666  C CD1 . LEU A 1 114 ? 135.598 110.751 107.539 1.00 62.33  ? 188 LEU A CD1 1 
ATOM 667  C CD2 . LEU A 1 114 ? 134.787 108.470 108.159 1.00 65.93  ? 188 LEU A CD2 1 
ATOM 668  N N   . TYR A 1 115 ? 138.202 106.936 104.415 1.00 52.15  ? 189 TYR A N   1 
ATOM 669  C CA  . TYR A 1 115 ? 138.411 106.336 103.103 1.00 52.71  ? 189 TYR A CA  1 
ATOM 670  C C   . TYR A 1 115 ? 138.612 104.831 103.204 1.00 58.64  ? 189 TYR A C   1 
ATOM 671  O O   . TYR A 1 115 ? 138.201 104.092 102.302 1.00 63.92  ? 189 TYR A O   1 
ATOM 672  C CB  . TYR A 1 115 ? 139.607 106.986 102.411 1.00 54.15  ? 189 TYR A CB  1 
ATOM 673  C CG  . TYR A 1 115 ? 139.921 106.400 101.055 1.00 53.11  ? 189 TYR A CG  1 
ATOM 674  C CD1 . TYR A 1 115 ? 139.201 106.777 99.933  1.00 56.54  ? 189 TYR A CD1 1 
ATOM 675  C CD2 . TYR A 1 115 ? 140.941 105.478 100.898 1.00 51.17  ? 189 TYR A CD2 1 
ATOM 676  C CE1 . TYR A 1 115 ? 139.486 106.246 98.693  1.00 59.71  ? 189 TYR A CE1 1 
ATOM 677  C CE2 . TYR A 1 115 ? 141.233 104.942 99.665  1.00 51.86  ? 189 TYR A CE2 1 
ATOM 678  C CZ  . TYR A 1 115 ? 140.504 105.328 98.566  1.00 59.38  ? 189 TYR A CZ  1 
ATOM 679  O OH  . TYR A 1 115 ? 140.794 104.794 97.331  1.00 62.99  ? 189 TYR A OH  1 
ATOM 680  N N   . ALA A 1 116 ? 139.245 104.361 104.281 1.00 56.69  ? 190 ALA A N   1 
ATOM 681  C CA  . ALA A 1 116 ? 139.446 102.926 104.452 1.00 57.64  ? 190 ALA A CA  1 
ATOM 682  C C   . ALA A 1 116 ? 138.117 102.194 104.585 1.00 56.94  ? 190 ALA A C   1 
ATOM 683  O O   . ALA A 1 116 ? 137.940 101.108 104.021 1.00 58.21  ? 190 ALA A O   1 
ATOM 684  C CB  . ALA A 1 116 ? 140.331 102.661 105.668 1.00 58.85  ? 190 ALA A CB  1 
ATOM 685  N N   . SER A 1 117 ? 137.171 102.770 105.330 1.00 61.85  ? 191 SER A N   1 
ATOM 686  C CA  . SER A 1 117 ? 135.860 102.144 105.465 1.00 61.53  ? 191 SER A CA  1 
ATOM 687  C C   . SER A 1 117 ? 135.093 102.163 104.152 1.00 64.17  ? 191 SER A C   1 
ATOM 688  O O   . SER A 1 117 ? 134.257 101.284 103.913 1.00 67.26  ? 191 SER A O   1 
ATOM 689  C CB  . SER A 1 117 ? 135.049 102.840 106.556 1.00 56.08  ? 191 SER A CB  1 
ATOM 690  O OG  . SER A 1 117 ? 134.860 104.209 106.253 1.00 59.79  ? 191 SER A OG  1 
ATOM 691  N N   . SER A 1 118 ? 135.353 103.155 103.298 1.00 62.64  ? 192 SER A N   1 
ATOM 692  C CA  . SER A 1 118 ? 134.635 103.246 102.032 1.00 61.80  ? 192 SER A CA  1 
ATOM 693  C C   . SER A 1 118 ? 134.932 102.049 101.141 1.00 61.16  ? 192 SER A C   1 
ATOM 694  O O   . SER A 1 118 ? 134.030 101.517 100.482 1.00 66.56  ? 192 SER A O   1 
ATOM 695  C CB  . SER A 1 118 ? 134.994 104.546 101.315 1.00 64.93  ? 192 SER A CB  1 
ATOM 696  O OG  . SER A 1 118 ? 136.376 104.593 101.015 1.00 67.12  ? 192 SER A OG  1 
ATOM 697  N N   . LEU A 1 119 ? 136.190 101.608 101.105 1.00 57.00  ? 193 LEU A N   1 
ATOM 698  C CA  . LEU A 1 119 ? 136.551 100.499 100.232 1.00 62.48  ? 193 LEU A CA  1 
ATOM 699  C C   . LEU A 1 119 ? 136.105 99.152  100.781 1.00 61.03  ? 193 LEU A C   1 
ATOM 700  O O   . LEU A 1 119 ? 136.155 98.156  100.053 1.00 61.65  ? 193 LEU A O   1 
ATOM 701  C CB  . LEU A 1 119 ? 138.060 100.485 99.990  1.00 58.01  ? 193 LEU A CB  1 
ATOM 702  C CG  . LEU A 1 119 ? 138.663 101.768 99.422  1.00 58.49  ? 193 LEU A CG  1 
ATOM 703  C CD1 . LEU A 1 119 ? 140.156 101.601 99.223  1.00 61.56  ? 193 LEU A CD1 1 
ATOM 704  C CD2 . LEU A 1 119 ? 137.984 102.142 98.117  1.00 61.04  ? 193 LEU A CD2 1 
ATOM 705  N N   . PHE A 1 120 ? 135.666 99.095  102.035 1.00 55.24  ? 194 PHE A N   1 
ATOM 706  C CA  . PHE A 1 120 ? 135.268 97.843  102.672 1.00 60.63  ? 194 PHE A CA  1 
ATOM 707  C C   . PHE A 1 120 ? 133.846 97.995  103.204 1.00 64.79  ? 194 PHE A C   1 
ATOM 708  O O   . PHE A 1 120 ? 133.639 98.377  104.358 1.00 58.56  ? 194 PHE A O   1 
ATOM 709  C CB  . PHE A 1 120 ? 136.242 97.460  103.780 1.00 60.87  ? 194 PHE A CB  1 
ATOM 710  C CG  . PHE A 1 120 ? 137.615 97.117  103.287 1.00 60.43  ? 194 PHE A CG  1 
ATOM 711  C CD1 . PHE A 1 120 ? 138.533 98.112  103.006 1.00 62.22  ? 194 PHE A CD1 1 
ATOM 712  C CD2 . PHE A 1 120 ? 137.989 95.799  103.106 1.00 58.09  ? 194 PHE A CD2 1 
ATOM 713  C CE1 . PHE A 1 120 ? 139.795 97.799  102.552 1.00 58.00  ? 194 PHE A CE1 1 
ATOM 714  C CE2 . PHE A 1 120 ? 139.250 95.481  102.653 1.00 61.53  ? 194 PHE A CE2 1 
ATOM 715  C CZ  . PHE A 1 120 ? 140.155 96.483  102.375 1.00 59.89  ? 194 PHE A CZ  1 
ATOM 716  N N   . GLN A 1 121 ? 132.865 97.694  102.353 1.00 66.51  ? 195 GLN A N   1 
ATOM 717  C CA  . GLN A 1 121 ? 131.475 97.676  102.785 1.00 64.14  ? 195 GLN A CA  1 
ATOM 718  C C   . GLN A 1 121 ? 131.129 96.424  103.578 1.00 61.29  ? 195 GLN A C   1 
ATOM 719  O O   . GLN A 1 121 ? 130.138 96.427  104.316 1.00 66.35  ? 195 GLN A O   1 
ATOM 720  C CB  . GLN A 1 121 ? 130.545 97.791  101.575 1.00 64.78  ? 195 GLN A CB  1 
ATOM 721  C CG  . GLN A 1 121 ? 130.700 99.082  100.790 1.00 64.65  ? 195 GLN A CG  1 
ATOM 722  C CD  . GLN A 1 121 ? 130.350 100.309 101.605 1.00 65.26  ? 195 GLN A CD  1 
ATOM 723  O OE1 . GLN A 1 121 ? 129.183 100.685 101.712 1.00 64.74  ? 195 GLN A OE1 1 
ATOM 724  N NE2 . GLN A 1 121 ? 131.363 100.946 102.180 1.00 62.44  ? 195 GLN A NE2 1 
ATOM 725  N N   . GLY A 1 122 ? 131.913 95.365  103.444 1.00 50.70  ? 196 GLY A N   1 
ATOM 726  C CA  . GLY A 1 122 ? 131.719 94.130  104.180 1.00 54.76  ? 196 GLY A CA  1 
ATOM 727  C C   . GLY A 1 122 ? 132.491 94.126  105.481 1.00 64.20  ? 196 GLY A C   1 
ATOM 728  O O   . GLY A 1 122 ? 132.518 95.121  106.213 1.00 68.68  ? 196 GLY A O   1 
ATOM 729  N N   . SER A 1 123 ? 133.132 92.997  105.772 1.00 66.36  ? 197 SER A N   1 
ATOM 730  C CA  . SER A 1 123 ? 133.931 92.870  106.984 1.00 61.88  ? 197 SER A CA  1 
ATOM 731  C C   . SER A 1 123 ? 135.293 93.512  106.759 1.00 65.93  ? 197 SER A C   1 
ATOM 732  O O   . SER A 1 123 ? 136.115 92.989  105.998 1.00 72.89  ? 197 SER A O   1 
ATOM 733  C CB  . SER A 1 123 ? 134.081 91.403  107.374 1.00 63.17  ? 197 SER A CB  1 
ATOM 734  O OG  . SER A 1 123 ? 134.714 90.664  106.345 1.00 71.10  ? 197 SER A OG  1 
ATOM 735  N N   . VAL A 1 124 ? 135.533 94.641  107.417 1.00 54.78  ? 198 VAL A N   1 
ATOM 736  C CA  . VAL A 1 124 ? 136.788 95.373  107.270 1.00 59.50  ? 198 VAL A CA  1 
ATOM 737  C C   . VAL A 1 124 ? 137.821 94.798  108.235 1.00 60.89  ? 198 VAL A C   1 
ATOM 738  O O   . VAL A 1 124 ? 137.508 94.549  109.408 1.00 62.41  ? 198 VAL A O   1 
ATOM 739  C CB  . VAL A 1 124 ? 136.572 96.884  107.470 1.00 48.80  ? 198 VAL A CB  1 
ATOM 740  C CG1 . VAL A 1 124 ? 136.078 97.182  108.866 1.00 51.50  ? 198 VAL A CG1 1 
ATOM 741  C CG2 . VAL A 1 124 ? 137.850 97.653  107.187 1.00 51.99  ? 198 VAL A CG2 1 
ATOM 742  N N   . PRO A 1 125 ? 139.041 94.532  107.779 1.00 58.73  ? 199 PRO A N   1 
ATOM 743  C CA  . PRO A 1 125 ? 140.069 93.977  108.667 1.00 55.54  ? 199 PRO A CA  1 
ATOM 744  C C   . PRO A 1 125 ? 140.538 95.017  109.668 1.00 57.38  ? 199 PRO A C   1 
ATOM 745  O O   . PRO A 1 125 ? 140.173 96.198  109.558 1.00 64.97  ? 199 PRO A O   1 
ATOM 746  C CB  . PRO A 1 125 ? 141.193 93.583  107.696 1.00 63.49  ? 199 PRO A CB  1 
ATOM 747  C CG  . PRO A 1 125 ? 140.980 94.438  106.502 1.00 61.73  ? 199 PRO A CG  1 
ATOM 748  C CD  . PRO A 1 125 ? 139.501 94.615  106.383 1.00 59.34  ? 199 PRO A CD  1 
ATOM 749  N N   . PRO A 1 126 ? 141.333 94.624  110.665 1.00 51.18  ? 200 PRO A N   1 
ATOM 750  C CA  . PRO A 1 126 ? 141.844 95.610  111.624 1.00 55.94  ? 200 PRO A CA  1 
ATOM 751  C C   . PRO A 1 126 ? 142.664 96.691  110.936 1.00 59.00  ? 200 PRO A C   1 
ATOM 752  O O   . PRO A 1 126 ? 143.405 96.428  109.987 1.00 65.51  ? 200 PRO A O   1 
ATOM 753  C CB  . PRO A 1 126 ? 142.704 94.770  112.576 1.00 60.85  ? 200 PRO A CB  1 
ATOM 754  C CG  . PRO A 1 126 ? 142.946 93.485  111.860 1.00 60.75  ? 200 PRO A CG  1 
ATOM 755  C CD  . PRO A 1 126 ? 141.724 93.257  111.040 1.00 56.71  ? 200 PRO A CD  1 
ATOM 756  N N   . VAL A 1 127 ? 142.518 97.918  111.426 1.00 59.90  ? 201 VAL A N   1 
ATOM 757  C CA  . VAL A 1 127 ? 143.148 99.091  110.835 1.00 58.44  ? 201 VAL A CA  1 
ATOM 758  C C   . VAL A 1 127 ? 144.007 99.763  111.893 1.00 56.94  ? 201 VAL A C   1 
ATOM 759  O O   . VAL A 1 127 ? 143.537 100.027 113.005 1.00 70.40  ? 201 VAL A O   1 
ATOM 760  C CB  . VAL A 1 127 ? 142.106 100.079 110.282 1.00 67.37  ? 201 VAL A CB  1 
ATOM 761  C CG1 . VAL A 1 127 ? 142.799 101.274 109.653 1.00 68.15  ? 201 VAL A CG1 1 
ATOM 762  C CG2 . VAL A 1 127 ? 141.195 99.391  109.279 1.00 68.34  ? 201 VAL A CG2 1 
ATOM 763  N N   . MET A 1 128 ? 145.259 100.038 111.547 1.00 55.97  ? 202 MET A N   1 
ATOM 764  C CA  . MET A 1 128 ? 146.179 100.760 112.413 1.00 64.66  ? 202 MET A CA  1 
ATOM 765  C C   . MET A 1 128 ? 146.508 102.089 111.752 1.00 62.64  ? 202 MET A C   1 
ATOM 766  O O   . MET A 1 128 ? 146.990 102.116 110.615 1.00 74.16  ? 202 MET A O   1 
ATOM 767  C CB  . MET A 1 128 ? 147.447 99.946  112.667 1.00 72.39  ? 202 MET A CB  1 
ATOM 768  C CG  . MET A 1 128 ? 148.511 100.681 113.461 1.00 76.87  ? 202 MET A CG  1 
ATOM 769  S SD  . MET A 1 128 ? 149.917 99.632  113.880 1.00 89.48  ? 202 MET A SD  1 
ATOM 770  C CE  . MET A 1 128 ? 150.413 99.061  112.259 1.00 70.33  ? 202 MET A CE  1 
ATOM 771  N N   . ALA A 1 129 ? 146.255 103.183 112.461 1.00 45.89  ? 203 ALA A N   1 
ATOM 772  C CA  . ALA A 1 129 ? 146.392 104.521 111.906 1.00 52.13  ? 203 ALA A CA  1 
ATOM 773  C C   . ALA A 1 129 ? 147.538 105.250 112.588 1.00 59.45  ? 203 ALA A C   1 
ATOM 774  O O   . ALA A 1 129 ? 147.645 105.237 113.819 1.00 64.21  ? 203 ALA A O   1 
ATOM 775  C CB  . ALA A 1 129 ? 145.094 105.312 112.059 1.00 59.87  ? 203 ALA A CB  1 
ATOM 776  N N   . PHE A 1 130 ? 148.387 105.882 111.785 1.00 63.85  ? 204 PHE A N   1 
ATOM 777  C CA  . PHE A 1 130 ? 149.524 106.651 112.267 1.00 63.08  ? 204 PHE A CA  1 
ATOM 778  C C   . PHE A 1 130 ? 149.272 108.136 112.052 1.00 66.56  ? 204 PHE A C   1 
ATOM 779  O O   . PHE A 1 130 ? 148.760 108.541 111.004 1.00 68.03  ? 204 PHE A O   1 
ATOM 780  C CB  . PHE A 1 130 ? 150.811 106.233 111.553 1.00 65.04  ? 204 PHE A CB  1 
ATOM 781  C CG  . PHE A 1 130 ? 151.240 104.825 111.844 1.00 63.99  ? 204 PHE A CG  1 
ATOM 782  C CD1 . PHE A 1 130 ? 150.730 103.764 111.121 1.00 66.78  ? 204 PHE A CD1 1 
ATOM 783  C CD2 . PHE A 1 130 ? 152.164 104.566 112.839 1.00 67.49  ? 204 PHE A CD2 1 
ATOM 784  C CE1 . PHE A 1 130 ? 151.130 102.471 111.393 1.00 67.50  ? 204 PHE A CE1 1 
ATOM 785  C CE2 . PHE A 1 130 ? 152.565 103.278 113.113 1.00 66.63  ? 204 PHE A CE2 1 
ATOM 786  C CZ  . PHE A 1 130 ? 152.049 102.230 112.390 1.00 64.80  ? 204 PHE A CZ  1 
ATOM 787  N N   . HIS A 1 131 ? 149.630 108.944 113.047 1.00 86.63  ? 205 HIS A N   1 
ATOM 788  C CA  . HIS A 1 131 ? 149.467 110.395 112.975 1.00 88.60  ? 205 HIS A CA  1 
ATOM 789  C C   . HIS A 1 131 ? 150.842 111.019 112.770 1.00 88.81  ? 205 HIS A C   1 
ATOM 790  O O   . HIS A 1 131 ? 151.737 110.875 113.607 1.00 86.52  ? 205 HIS A O   1 
ATOM 791  C CB  . HIS A 1 131 ? 148.785 110.938 114.227 1.00 87.62  ? 205 HIS A CB  1 
ATOM 792  C CG  . HIS A 1 131 ? 149.534 110.671 115.494 1.00 87.80  ? 205 HIS A CG  1 
ATOM 793  N ND1 . HIS A 1 131 ? 149.549 109.436 116.105 1.00 91.23  ? 205 HIS A ND1 1 
ATOM 794  C CD2 . HIS A 1 131 ? 150.296 111.482 116.266 1.00 89.67  ? 205 HIS A CD2 1 
ATOM 795  C CE1 . HIS A 1 131 ? 150.285 109.498 117.200 1.00 90.61  ? 205 HIS A CE1 1 
ATOM 796  N NE2 . HIS A 1 131 ? 150.752 110.728 117.319 1.00 89.96  ? 205 HIS A NE2 1 
ATOM 797  N N   . LEU A 1 132 ? 151.009 111.709 111.645 1.00 103.11 ? 206 LEU A N   1 
ATOM 798  C CA  . LEU A 1 132 ? 152.266 112.382 111.320 1.00 102.74 ? 206 LEU A CA  1 
ATOM 799  C C   . LEU A 1 132 ? 152.026 113.881 111.424 1.00 104.45 ? 206 LEU A C   1 
ATOM 800  O O   . LEU A 1 132 ? 151.639 114.542 110.459 1.00 104.01 ? 206 LEU A O   1 
ATOM 801  C CB  . LEU A 1 132 ? 152.756 111.976 109.936 1.00 102.22 ? 206 LEU A CB  1 
ATOM 802  C CG  . LEU A 1 132 ? 153.135 110.504 109.747 1.00 100.75 ? 206 LEU A CG  1 
ATOM 803  C CD1 . LEU A 1 132 ? 151.926 109.653 109.378 1.00 100.49 ? 206 LEU A CD1 1 
ATOM 804  C CD2 . LEU A 1 132 ? 154.221 110.369 108.701 1.00 100.19 ? 206 LEU A CD2 1 
ATOM 805  N N   . GLY A 1 133 ? 152.261 114.426 112.615 1.00 110.90 ? 207 GLY A N   1 
ATOM 806  C CA  . GLY A 1 133 ? 151.973 115.822 112.875 1.00 110.39 ? 207 GLY A CA  1 
ATOM 807  C C   . GLY A 1 133 ? 150.735 115.996 113.728 1.00 111.78 ? 207 GLY A C   1 
ATOM 808  O O   . GLY A 1 133 ? 150.777 115.786 114.944 1.00 111.04 ? 207 GLY A O   1 
ATOM 809  N N   . SER A 1 134 ? 149.628 116.387 113.104 1.00 110.54 ? 208 SER A N   1 
ATOM 810  C CA  . SER A 1 134 ? 148.368 116.508 113.821 1.00 109.40 ? 208 SER A CA  1 
ATOM 811  C C   . SER A 1 134 ? 147.875 115.138 114.273 1.00 107.97 ? 208 SER A C   1 
ATOM 812  O O   . SER A 1 134 ? 147.976 114.144 113.549 1.00 108.28 ? 208 SER A O   1 
ATOM 813  C CB  . SER A 1 134 ? 147.314 117.178 112.939 1.00 108.64 ? 208 SER A CB  1 
ATOM 814  O OG  . SER A 1 134 ? 147.096 116.436 111.752 1.00 109.13 ? 208 SER A OG  1 
ATOM 815  N N   . LEU A 1 135 ? 147.337 115.093 115.488 1.00 98.62  ? 209 LEU A N   1 
ATOM 816  C CA  . LEU A 1 135 ? 146.841 113.862 116.088 1.00 99.84  ? 209 LEU A CA  1 
ATOM 817  C C   . LEU A 1 135 ? 145.319 113.895 116.108 1.00 100.74 ? 209 LEU A C   1 
ATOM 818  O O   . LEU A 1 135 ? 144.721 114.872 116.571 1.00 100.29 ? 209 LEU A O   1 
ATOM 819  C CB  . LEU A 1 135 ? 147.403 113.682 117.502 1.00 101.36 ? 209 LEU A CB  1 
ATOM 820  C CG  . LEU A 1 135 ? 147.161 112.365 118.247 1.00 101.44 ? 209 LEU A CG  1 
ATOM 821  C CD1 . LEU A 1 135 ? 148.311 112.093 119.201 1.00 100.12 ? 209 LEU A CD1 1 
ATOM 822  C CD2 . LEU A 1 135 ? 145.849 112.392 119.018 1.00 99.60  ? 209 LEU A CD2 1 
ATOM 823  N N   . GLY A 1 136 ? 144.700 112.826 115.608 1.00 92.56  ? 210 GLY A N   1 
ATOM 824  C CA  . GLY A 1 136 ? 143.263 112.724 115.533 1.00 90.69  ? 210 GLY A CA  1 
ATOM 825  C C   . GLY A 1 136 ? 142.689 111.727 116.521 1.00 92.07  ? 210 GLY A C   1 
ATOM 826  O O   . GLY A 1 136 ? 143.395 111.122 117.330 1.00 93.47  ? 210 GLY A O   1 
ATOM 827  N N   . PHE A 1 137 ? 141.370 111.560 116.439 1.00 86.18  ? 211 PHE A N   1 
ATOM 828  C CA  . PHE A 1 137 ? 140.658 110.660 117.336 1.00 83.87  ? 211 PHE A CA  1 
ATOM 829  C C   . PHE A 1 137 ? 140.747 109.203 116.908 1.00 84.24  ? 211 PHE A C   1 
ATOM 830  O O   . PHE A 1 137 ? 140.384 108.321 117.694 1.00 86.11  ? 211 PHE A O   1 
ATOM 831  C CB  . PHE A 1 137 ? 139.188 111.071 117.434 1.00 82.38  ? 211 PHE A CB  1 
ATOM 832  C CG  . PHE A 1 137 ? 138.972 112.369 118.151 1.00 82.75  ? 211 PHE A CG  1 
ATOM 833  C CD1 . PHE A 1 137 ? 138.856 112.405 119.527 1.00 84.54  ? 211 PHE A CD1 1 
ATOM 834  C CD2 . PHE A 1 137 ? 138.884 113.556 117.445 1.00 83.41  ? 211 PHE A CD2 1 
ATOM 835  C CE1 . PHE A 1 137 ? 138.659 113.600 120.187 1.00 86.63  ? 211 PHE A CE1 1 
ATOM 836  C CE2 . PHE A 1 137 ? 138.685 114.754 118.098 1.00 84.25  ? 211 PHE A CE2 1 
ATOM 837  C CZ  . PHE A 1 137 ? 138.572 114.776 119.472 1.00 85.17  ? 211 PHE A CZ  1 
ATOM 838  N N   . LEU A 1 138 ? 141.214 108.929 115.692 1.00 79.41  ? 212 LEU A N   1 
ATOM 839  C CA  . LEU A 1 138 ? 141.284 107.572 115.170 1.00 80.77  ? 212 LEU A CA  1 
ATOM 840  C C   . LEU A 1 138 ? 142.714 107.120 114.901 1.00 86.83  ? 212 LEU A C   1 
ATOM 841  O O   . LEU A 1 138 ? 142.914 106.045 114.324 1.00 87.66  ? 212 LEU A O   1 
ATOM 842  C CB  . LEU A 1 138 ? 140.452 107.464 113.890 1.00 82.03  ? 212 LEU A CB  1 
ATOM 843  C CG  . LEU A 1 138 ? 139.054 108.080 113.964 1.00 82.38  ? 212 LEU A CG  1 
ATOM 844  C CD1 . LEU A 1 138 ? 138.352 108.007 112.617 1.00 83.75  ? 212 LEU A CD1 1 
ATOM 845  C CD2 . LEU A 1 138 ? 138.225 107.400 115.040 1.00 83.03  ? 212 LEU A CD2 1 
ATOM 846  N N   . THR A 1 139 ? 143.713 107.904 115.308 1.00 87.71  ? 213 THR A N   1 
ATOM 847  C CA  . THR A 1 139 ? 145.117 107.653 114.978 1.00 82.55  ? 213 THR A CA  1 
ATOM 848  C C   . THR A 1 139 ? 145.936 107.633 116.261 1.00 76.34  ? 213 THR A C   1 
ATOM 849  O O   . THR A 1 139 ? 146.565 108.635 116.627 1.00 79.24  ? 213 THR A O   1 
ATOM 850  C CB  . THR A 1 139 ? 145.654 108.712 114.016 1.00 84.77  ? 213 THR A CB  1 
ATOM 851  O OG1 . THR A 1 139 ? 145.717 109.976 114.688 1.00 86.97  ? 213 THR A OG1 1 
ATOM 852  C CG2 . THR A 1 139 ? 144.743 108.845 112.812 1.00 81.50  ? 213 THR A CG2 1 
ATOM 853  N N   . PRO A 1 140 ? 145.950 106.511 116.972 1.00 74.34  ? 214 PRO A N   1 
ATOM 854  C CA  . PRO A 1 140 ? 146.665 106.462 118.254 1.00 82.56  ? 214 PRO A CA  1 
ATOM 855  C C   . PRO A 1 140 ? 148.169 106.275 118.122 1.00 85.95  ? 214 PRO A C   1 
ATOM 856  O O   . PRO A 1 140 ? 148.935 106.825 118.920 1.00 86.65  ? 214 PRO A O   1 
ATOM 857  C CB  . PRO A 1 140 ? 146.019 105.264 118.958 1.00 82.93  ? 214 PRO A CB  1 
ATOM 858  C CG  . PRO A 1 140 ? 145.610 104.371 117.840 1.00 83.53  ? 214 PRO A CG  1 
ATOM 859  C CD  . PRO A 1 140 ? 145.196 105.274 116.709 1.00 78.23  ? 214 PRO A CD  1 
ATOM 860  N N   . PHE A 1 141 ? 148.607 105.508 117.127 1.00 79.91  ? 215 PHE A N   1 
ATOM 861  C CA  . PHE A 1 141 ? 150.006 105.110 117.036 1.00 75.57  ? 215 PHE A CA  1 
ATOM 862  C C   . PHE A 1 141 ? 150.880 106.246 116.522 1.00 75.19  ? 215 PHE A C   1 
ATOM 863  O O   . PHE A 1 141 ? 150.536 106.927 115.553 1.00 78.63  ? 215 PHE A O   1 
ATOM 864  C CB  . PHE A 1 141 ? 150.156 103.891 116.129 1.00 74.64  ? 215 PHE A CB  1 
ATOM 865  C CG  . PHE A 1 141 ? 149.701 102.610 116.760 1.00 71.95  ? 215 PHE A CG  1 
ATOM 866  C CD1 . PHE A 1 141 ? 148.392 102.190 116.638 1.00 71.75  ? 215 PHE A CD1 1 
ATOM 867  C CD2 . PHE A 1 141 ? 150.586 101.829 117.480 1.00 77.57  ? 215 PHE A CD2 1 
ATOM 868  C CE1 . PHE A 1 141 ? 147.972 101.012 117.217 1.00 75.38  ? 215 PHE A CE1 1 
ATOM 869  C CE2 . PHE A 1 141 ? 150.172 100.650 118.065 1.00 79.01  ? 215 PHE A CE2 1 
ATOM 870  C CZ  . PHE A 1 141 ? 148.863 100.241 117.933 1.00 80.18  ? 215 PHE A CZ  1 
ATOM 871  N N   . SER A 1 142 ? 152.020 106.438 117.178 1.00 77.85  ? 216 SER A N   1 
ATOM 872  C CA  . SER A 1 142 ? 153.010 107.415 116.756 1.00 82.19  ? 216 SER A CA  1 
ATOM 873  C C   . SER A 1 142 ? 153.990 106.779 115.779 1.00 85.15  ? 216 SER A C   1 
ATOM 874  O O   . SER A 1 142 ? 154.253 105.575 115.829 1.00 85.95  ? 216 SER A O   1 
ATOM 875  C CB  . SER A 1 142 ? 153.763 107.978 117.962 1.00 85.83  ? 216 SER A CB  1 
ATOM 876  O OG  . SER A 1 142 ? 154.667 108.997 117.571 1.00 88.64  ? 216 SER A OG  1 
ATOM 877  N N   . PHE A 1 143 ? 154.533 107.604 114.883 1.00 95.72  ? 217 PHE A N   1 
ATOM 878  C CA  . PHE A 1 143 ? 155.396 107.087 113.829 1.00 95.17  ? 217 PHE A CA  1 
ATOM 879  C C   . PHE A 1 143 ? 156.800 106.751 114.315 1.00 97.51  ? 217 PHE A C   1 
ATOM 880  O O   . PHE A 1 143 ? 157.503 105.988 113.644 1.00 98.96  ? 217 PHE A O   1 
ATOM 881  C CB  . PHE A 1 143 ? 155.481 108.086 112.673 1.00 96.46  ? 217 PHE A CB  1 
ATOM 882  C CG  . PHE A 1 143 ? 156.082 107.508 111.425 1.00 98.09  ? 217 PHE A CG  1 
ATOM 883  C CD1 . PHE A 1 143 ? 155.343 106.667 110.612 1.00 95.78  ? 217 PHE A CD1 1 
ATOM 884  C CD2 . PHE A 1 143 ? 157.388 107.800 111.069 1.00 97.76  ? 217 PHE A CD2 1 
ATOM 885  C CE1 . PHE A 1 143 ? 155.893 106.129 109.466 1.00 96.15  ? 217 PHE A CE1 1 
ATOM 886  C CE2 . PHE A 1 143 ? 157.944 107.265 109.923 1.00 96.83  ? 217 PHE A CE2 1 
ATOM 887  C CZ  . PHE A 1 143 ? 157.194 106.428 109.121 1.00 96.71  ? 217 PHE A CZ  1 
ATOM 888  N N   . GLU A 1 144 ? 157.224 107.291 115.454 1.00 103.17 ? 218 GLU A N   1 
ATOM 889  C CA  . GLU A 1 144 ? 158.552 106.983 115.967 1.00 102.48 ? 218 GLU A CA  1 
ATOM 890  C C   . GLU A 1 144 ? 158.637 105.518 116.375 1.00 102.11 ? 218 GLU A C   1 
ATOM 891  O O   . GLU A 1 144 ? 157.706 104.966 116.968 1.00 102.48 ? 218 GLU A O   1 
ATOM 892  C CB  . GLU A 1 144 ? 158.890 107.892 117.150 1.00 102.52 ? 218 GLU A CB  1 
ATOM 893  C CG  . GLU A 1 144 ? 157.843 107.921 118.256 1.00 103.80 ? 218 GLU A CG  1 
ATOM 894  C CD  . GLU A 1 144 ? 158.075 106.859 119.314 1.00 104.46 ? 218 GLU A CD  1 
ATOM 895  O OE1 . GLU A 1 144 ? 159.187 106.291 119.355 1.00 104.52 ? 218 GLU A OE1 1 
ATOM 896  O OE2 . GLU A 1 144 ? 157.146 106.593 120.105 1.00 101.73 ? 218 GLU A OE2 1 
ATOM 897  N N   . ASN A 1 145 ? 159.766 104.888 116.045 1.00 95.78  ? 219 ASN A N   1 
ATOM 898  C CA  . ASN A 1 145 ? 159.980 103.462 116.286 1.00 95.88  ? 219 ASN A CA  1 
ATOM 899  C C   . ASN A 1 145 ? 158.842 102.632 115.695 1.00 94.81  ? 219 ASN A C   1 
ATOM 900  O O   . ASN A 1 145 ? 158.288 101.737 116.336 1.00 94.54  ? 219 ASN A O   1 
ATOM 901  C CB  . ASN A 1 145 ? 160.155 103.176 117.778 1.00 96.46  ? 219 ASN A CB  1 
ATOM 902  C CG  . ASN A 1 145 ? 160.737 101.800 118.044 1.00 97.31  ? 219 ASN A CG  1 
ATOM 903  O OD1 . ASN A 1 145 ? 161.271 101.155 117.143 1.00 96.69  ? 219 ASN A OD1 1 
ATOM 904  N ND2 . ASN A 1 145 ? 160.634 101.344 119.287 1.00 97.40  ? 219 ASN A ND2 1 
ATOM 905  N N   . PHE A 1 146 ? 158.489 102.946 114.447 1.00 93.89  ? 220 PHE A N   1 
ATOM 906  C CA  . PHE A 1 146 ? 157.373 102.259 113.807 1.00 94.53  ? 220 PHE A CA  1 
ATOM 907  C C   . PHE A 1 146 ? 157.678 100.788 113.557 1.00 95.73  ? 220 PHE A C   1 
ATOM 908  O O   . PHE A 1 146 ? 156.756 99.967  113.537 1.00 97.11  ? 220 PHE A O   1 
ATOM 909  C CB  . PHE A 1 146 ? 156.996 102.959 112.500 1.00 95.13  ? 220 PHE A CB  1 
ATOM 910  C CG  . PHE A 1 146 ? 158.006 102.793 111.401 1.00 95.75  ? 220 PHE A CG  1 
ATOM 911  C CD1 . PHE A 1 146 ? 159.100 103.636 111.315 1.00 97.03  ? 220 PHE A CD1 1 
ATOM 912  C CD2 . PHE A 1 146 ? 157.852 101.805 110.443 1.00 96.10  ? 220 PHE A CD2 1 
ATOM 913  C CE1 . PHE A 1 146 ? 160.026 103.491 110.301 1.00 98.27  ? 220 PHE A CE1 1 
ATOM 914  C CE2 . PHE A 1 146 ? 158.775 101.653 109.428 1.00 97.26  ? 220 PHE A CE2 1 
ATOM 915  C CZ  . PHE A 1 146 ? 159.864 102.497 109.356 1.00 97.81  ? 220 PHE A CZ  1 
ATOM 916  N N   . GLN A 1 147 ? 158.952 100.435 113.368 1.00 99.21  ? 221 GLN A N   1 
ATOM 917  C CA  . GLN A 1 147 ? 159.296 99.038  113.116 1.00 98.39  ? 221 GLN A CA  1 
ATOM 918  C C   . GLN A 1 147 ? 158.891 98.155  114.290 1.00 97.36  ? 221 GLN A C   1 
ATOM 919  O O   . GLN A 1 147 ? 158.308 97.082  114.102 1.00 99.21  ? 221 GLN A O   1 
ATOM 920  C CB  . GLN A 1 147 ? 160.792 98.899  112.834 1.00 96.03  ? 221 GLN A CB  1 
ATOM 921  C CG  . GLN A 1 147 ? 161.282 99.631  111.595 1.00 94.91  ? 221 GLN A CG  1 
ATOM 922  C CD  . GLN A 1 147 ? 161.725 101.049 111.892 1.00 97.89  ? 221 GLN A CD  1 
ATOM 923  O OE1 . GLN A 1 147 ? 161.358 101.626 112.915 1.00 98.60  ? 221 GLN A OE1 1 
ATOM 924  N NE2 . GLN A 1 147 ? 162.530 101.614 111.000 1.00 98.57  ? 221 GLN A NE2 1 
ATOM 925  N N   . SER A 1 148 ? 159.189 98.597  115.513 1.00 96.81  ? 222 SER A N   1 
ATOM 926  C CA  . SER A 1 148 ? 158.823 97.812  116.688 1.00 98.35  ? 222 SER A CA  1 
ATOM 927  C C   . SER A 1 148 ? 157.311 97.707  116.835 1.00 98.49  ? 222 SER A C   1 
ATOM 928  O O   . SER A 1 148 ? 156.786 96.639  117.174 1.00 98.75  ? 222 SER A O   1 
ATOM 929  C CB  . SER A 1 148 ? 159.444 98.426  117.942 1.00 97.07  ? 222 SER A CB  1 
ATOM 930  O OG  . SER A 1 148 ? 159.098 97.683  119.098 1.00 96.47  ? 222 SER A OG  1 
ATOM 931  N N   . GLN A 1 149 ? 156.595 98.805  116.587 1.00 91.16  ? 223 GLN A N   1 
ATOM 932  C CA  . GLN A 1 149 ? 155.143 98.797  116.734 1.00 89.40  ? 223 GLN A CA  1 
ATOM 933  C C   . GLN A 1 149 ? 154.483 97.890  115.702 1.00 90.97  ? 223 GLN A C   1 
ATOM 934  O O   . GLN A 1 149 ? 153.529 97.171  116.021 1.00 92.16  ? 223 GLN A O   1 
ATOM 935  C CB  . GLN A 1 149 ? 154.605 100.222 116.625 1.00 86.43  ? 223 GLN A CB  1 
ATOM 936  C CG  . GLN A 1 149 ? 155.190 101.177 117.648 1.00 83.93  ? 223 GLN A CG  1 
ATOM 937  C CD  . GLN A 1 149 ? 154.637 102.579 117.517 1.00 89.29  ? 223 GLN A CD  1 
ATOM 938  O OE1 . GLN A 1 149 ? 153.744 102.832 116.709 1.00 93.10  ? 223 GLN A OE1 1 
ATOM 939  N NE2 . GLN A 1 149 ? 155.167 103.501 118.310 1.00 90.24  ? 223 GLN A NE2 1 
ATOM 940  N N   . VAL A 1 150 ? 154.972 97.912  114.460 1.00 84.87  ? 224 VAL A N   1 
ATOM 941  C CA  . VAL A 1 150 ? 154.378 97.081  113.417 1.00 85.97  ? 224 VAL A CA  1 
ATOM 942  C C   . VAL A 1 150 ? 154.637 95.606  113.690 1.00 82.57  ? 224 VAL A C   1 
ATOM 943  O O   . VAL A 1 150 ? 153.759 94.760  113.485 1.00 85.10  ? 224 VAL A O   1 
ATOM 944  C CB  . VAL A 1 150 ? 154.900 97.506  112.032 1.00 90.29  ? 224 VAL A CB  1 
ATOM 945  C CG1 . VAL A 1 150 ? 154.418 96.542  110.963 1.00 89.98  ? 224 VAL A CG1 1 
ATOM 946  C CG2 . VAL A 1 150 ? 154.439 98.916  111.705 1.00 91.27  ? 224 VAL A CG2 1 
ATOM 947  N N   . THR A 1 151 ? 155.840 95.271  114.162 1.00 85.48  ? 225 THR A N   1 
ATOM 948  C CA  . THR A 1 151 ? 156.148 93.877  114.467 1.00 90.45  ? 225 THR A CA  1 
ATOM 949  C C   . THR A 1 151 ? 155.260 93.345  115.584 1.00 92.98  ? 225 THR A C   1 
ATOM 950  O O   . THR A 1 151 ? 154.862 92.175  115.566 1.00 93.73  ? 225 THR A O   1 
ATOM 951  C CB  . THR A 1 151 ? 157.623 93.727  114.838 1.00 93.77  ? 225 THR A CB  1 
ATOM 952  O OG1 . THR A 1 151 ? 157.954 94.652  115.882 1.00 91.78  ? 225 THR A OG1 1 
ATOM 953  C CG2 . THR A 1 151 ? 158.511 93.973  113.626 1.00 94.41  ? 225 THR A CG2 1 
ATOM 954  N N   . GLN A 1 152 ? 154.946 94.187  116.571 1.00 98.08  ? 226 GLN A N   1 
ATOM 955  C CA  . GLN A 1 152 ? 154.079 93.751  117.661 1.00 96.97  ? 226 GLN A CA  1 
ATOM 956  C C   . GLN A 1 152 ? 152.678 93.423  117.158 1.00 98.18  ? 226 GLN A C   1 
ATOM 957  O O   . GLN A 1 152 ? 152.071 92.438  117.592 1.00 99.77  ? 226 GLN A O   1 
ATOM 958  C CB  . GLN A 1 152 ? 154.023 94.821  118.750 1.00 94.02  ? 226 GLN A CB  1 
ATOM 959  C CG  . GLN A 1 152 ? 153.327 94.367  120.022 1.00 96.62  ? 226 GLN A CG  1 
ATOM 960  C CD  . GLN A 1 152 ? 153.365 95.415  121.116 1.00 99.68  ? 226 GLN A CD  1 
ATOM 961  O OE1 . GLN A 1 152 ? 153.913 96.502  120.932 1.00 99.14  ? 226 GLN A OE1 1 
ATOM 962  N NE2 . GLN A 1 152 ? 152.782 95.092  122.264 1.00 99.81  ? 226 GLN A NE2 1 
ATOM 963  N N   . VAL A 1 153 ? 152.145 94.239  116.247 1.00 83.85  ? 227 VAL A N   1 
ATOM 964  C CA  . VAL A 1 153 ? 150.812 93.978  115.711 1.00 77.43  ? 227 VAL A CA  1 
ATOM 965  C C   . VAL A 1 153 ? 150.808 92.705  114.874 1.00 78.44  ? 227 VAL A C   1 
ATOM 966  O O   . VAL A 1 153 ? 149.889 91.883  114.974 1.00 75.67  ? 227 VAL A O   1 
ATOM 967  C CB  . VAL A 1 153 ? 150.319 95.188  114.900 1.00 76.18  ? 227 VAL A CB  1 
ATOM 968  C CG1 . VAL A 1 153 ? 149.052 94.837  114.150 1.00 78.05  ? 227 VAL A CG1 1 
ATOM 969  C CG2 . VAL A 1 153 ? 150.091 96.377  115.815 1.00 81.91  ? 227 VAL A CG2 1 
ATOM 970  N N   . ILE A 1 154 ? 151.828 92.522  114.035 1.00 95.90  ? 228 ILE A N   1 
ATOM 971  C CA  . ILE A 1 154 ? 151.895 91.335  113.188 1.00 94.29  ? 228 ILE A CA  1 
ATOM 972  C C   . ILE A 1 154 ? 152.093 90.081  114.031 1.00 93.63  ? 228 ILE A C   1 
ATOM 973  O O   . ILE A 1 154 ? 151.396 89.076  113.850 1.00 95.88  ? 228 ILE A O   1 
ATOM 974  C CB  . ILE A 1 154 ? 153.010 91.489  112.138 1.00 93.18  ? 228 ILE A CB  1 
ATOM 975  C CG1 . ILE A 1 154 ? 152.764 92.724  111.271 1.00 91.14  ? 228 ILE A CG1 1 
ATOM 976  C CG2 . ILE A 1 154 ? 153.129 90.234  111.288 1.00 94.55  ? 228 ILE A CG2 1 
ATOM 977  C CD1 . ILE A 1 154 ? 153.859 92.985  110.269 1.00 92.11  ? 228 ILE A CD1 1 
ATOM 978  N N   . GLU A 1 155 ? 153.040 90.120  114.968 1.00 100.80 ? 229 GLU A N   1 
ATOM 979  C CA  . GLU A 1 155 ? 153.378 88.918  115.724 1.00 102.90 ? 229 GLU A CA  1 
ATOM 980  C C   . GLU A 1 155 ? 152.518 88.784  116.976 1.00 105.83 ? 229 GLU A C   1 
ATOM 981  O O   . GLU A 1 155 ? 151.799 87.794  117.145 1.00 106.61 ? 229 GLU A O   1 
ATOM 982  C CB  . GLU A 1 155 ? 154.866 88.930  116.086 1.00 103.41 ? 229 GLU A CB  1 
ATOM 983  C CG  . GLU A 1 155 ? 155.793 88.906  114.882 1.00 105.74 ? 229 GLU A CG  1 
ATOM 984  C CD  . GLU A 1 155 ? 157.258 88.896  115.271 1.00 106.81 ? 229 GLU A CD  1 
ATOM 985  O OE1 . GLU A 1 155 ? 157.555 89.009  116.479 1.00 105.75 ? 229 GLU A OE1 1 
ATOM 986  O OE2 . GLU A 1 155 ? 158.113 88.776  114.369 1.00 107.00 ? 229 GLU A OE2 1 
ATOM 987  N N   . GLY A 1 156 ? 152.576 89.774  117.860 1.00 109.30 ? 230 GLY A N   1 
ATOM 988  C CA  . GLY A 1 156 ? 151.845 89.726  119.107 1.00 108.23 ? 230 GLY A CA  1 
ATOM 989  C C   . GLY A 1 156 ? 150.408 90.186  118.950 1.00 108.98 ? 230 GLY A C   1 
ATOM 990  O O   . GLY A 1 156 ? 149.888 90.367  117.848 1.00 110.00 ? 230 GLY A O   1 
ATOM 991  N N   . ASN A 1 157 ? 149.758 90.374  120.094 1.00 113.08 ? 231 ASN A N   1 
ATOM 992  C CA  . ASN A 1 157 ? 148.369 90.804  120.153 1.00 115.36 ? 231 ASN A CA  1 
ATOM 993  C C   . ASN A 1 157 ? 148.298 92.229  120.684 1.00 113.43 ? 231 ASN A C   1 
ATOM 994  O O   . ASN A 1 157 ? 148.957 92.560  121.675 1.00 111.75 ? 231 ASN A O   1 
ATOM 995  C CB  . ASN A 1 157 ? 147.543 89.867  121.037 1.00 115.44 ? 231 ASN A CB  1 
ATOM 996  C CG  . ASN A 1 157 ? 147.456 88.462  120.476 1.00 116.60 ? 231 ASN A CG  1 
ATOM 997  O OD1 . ASN A 1 157 ? 148.253 88.070  119.624 1.00 116.98 ? 231 ASN A OD1 1 
ATOM 998  N ND2 . ASN A 1 157 ? 146.483 87.693  120.953 1.00 115.84 ? 231 ASN A ND2 1 
ATOM 999  N N   . ALA A 1 158 ? 147.503 93.066  120.022 1.00 104.51 ? 232 ALA A N   1 
ATOM 1000 C CA  . ALA A 1 158 ? 147.267 94.438  120.445 1.00 104.35 ? 232 ALA A CA  1 
ATOM 1001 C C   . ALA A 1 158 ? 145.769 94.694  120.521 1.00 106.57 ? 232 ALA A C   1 
ATOM 1002 O O   . ALA A 1 158 ? 145.021 94.320  119.613 1.00 107.91 ? 232 ALA A O   1 
ATOM 1003 C CB  . ALA A 1 158 ? 147.927 95.433  119.491 1.00 101.83 ? 232 ALA A CB  1 
ATOM 1004 N N   . ALA A 1 159 ? 145.340 95.347  121.599 1.00 98.88  ? 233 ALA A N   1 
ATOM 1005 C CA  . ALA A 1 159 ? 143.921 95.540  121.859 1.00 93.06  ? 233 ALA A CA  1 
ATOM 1006 C C   . ALA A 1 159 ? 143.277 96.408  120.784 1.00 95.44  ? 233 ALA A C   1 
ATOM 1007 O O   . ALA A 1 159 ? 143.919 97.274  120.183 1.00 97.83  ? 233 ALA A O   1 
ATOM 1008 C CB  . ALA A 1 159 ? 143.713 96.175  123.234 1.00 90.96  ? 233 ALA A CB  1 
ATOM 1009 N N   . VAL A 1 160 ? 141.986 96.169  120.547 1.00 81.21  ? 234 VAL A N   1 
ATOM 1010 C CA  . VAL A 1 160 ? 141.249 96.826  119.478 1.00 81.83  ? 234 VAL A CA  1 
ATOM 1011 C C   . VAL A 1 160 ? 139.944 97.388  120.023 1.00 80.53  ? 234 VAL A C   1 
ATOM 1012 O O   . VAL A 1 160 ? 139.462 96.995  121.087 1.00 78.97  ? 234 VAL A O   1 
ATOM 1013 C CB  . VAL A 1 160 ? 140.960 95.870  118.301 1.00 78.51  ? 234 VAL A CB  1 
ATOM 1014 C CG1 . VAL A 1 160 ? 142.249 95.489  117.594 1.00 80.75  ? 234 VAL A CG1 1 
ATOM 1015 C CG2 . VAL A 1 160 ? 140.232 94.635  118.795 1.00 76.24  ? 234 VAL A CG2 1 
ATOM 1016 N N   . VAL A 1 161 ? 139.378 98.329  119.271 1.00 75.89  ? 235 VAL A N   1 
ATOM 1017 C CA  . VAL A 1 161 ? 138.061 98.894  119.543 1.00 72.83  ? 235 VAL A CA  1 
ATOM 1018 C C   . VAL A 1 161 ? 137.173 98.594  118.345 1.00 72.56  ? 235 VAL A C   1 
ATOM 1019 O O   . VAL A 1 161 ? 137.475 99.018  117.222 1.00 74.03  ? 235 VAL A O   1 
ATOM 1020 C CB  . VAL A 1 161 ? 138.126 100.406 119.803 1.00 70.85  ? 235 VAL A CB  1 
ATOM 1021 C CG1 . VAL A 1 161 ? 136.730 101.001 119.807 1.00 70.00  ? 235 VAL A CG1 1 
ATOM 1022 C CG2 . VAL A 1 161 ? 138.810 100.680 121.117 1.00 71.16  ? 235 VAL A CG2 1 
ATOM 1023 N N   . LEU A 1 162 ? 136.082 97.870  118.579 1.00 59.00  ? 236 LEU A N   1 
ATOM 1024 C CA  . LEU A 1 162 ? 135.142 97.536  117.512 1.00 55.75  ? 236 LEU A CA  1 
ATOM 1025 C C   . LEU A 1 162 ? 134.203 98.719  117.321 1.00 58.37  ? 236 LEU A C   1 
ATOM 1026 O O   . LEU A 1 162 ? 133.121 98.788  117.905 1.00 60.96  ? 236 LEU A O   1 
ATOM 1027 C CB  . LEU A 1 162 ? 134.379 96.259  117.838 1.00 59.44  ? 236 LEU A CB  1 
ATOM 1028 C CG  . LEU A 1 162 ? 135.211 94.982  117.932 1.00 60.51  ? 236 LEU A CG  1 
ATOM 1029 C CD1 . LEU A 1 162 ? 134.315 93.785  118.195 1.00 58.08  ? 236 LEU A CD1 1 
ATOM 1030 C CD2 . LEU A 1 162 ? 136.016 94.781  116.663 1.00 59.47  ? 236 LEU A CD2 1 
ATOM 1031 N N   . ARG A 1 163 ? 134.629 99.662  116.488 1.00 58.81  ? 237 ARG A N   1 
ATOM 1032 C CA  . ARG A 1 163 ? 133.848 100.865 116.247 1.00 62.64  ? 237 ARG A CA  1 
ATOM 1033 C C   . ARG A 1 163 ? 132.608 100.536 115.427 1.00 63.94  ? 237 ARG A C   1 
ATOM 1034 O O   . ARG A 1 163 ? 132.665 99.735  114.489 1.00 67.56  ? 237 ARG A O   1 
ATOM 1035 C CB  . ARG A 1 163 ? 134.701 101.906 115.529 1.00 65.33  ? 237 ARG A CB  1 
ATOM 1036 C CG  . ARG A 1 163 ? 136.129 101.984 116.036 1.00 66.40  ? 237 ARG A CG  1 
ATOM 1037 C CD  . ARG A 1 163 ? 136.863 103.174 115.449 1.00 64.48  ? 237 ARG A CD  1 
ATOM 1038 N NE  . ARG A 1 163 ? 136.643 104.388 116.222 1.00 62.96  ? 237 ARG A NE  1 
ATOM 1039 C CZ  . ARG A 1 163 ? 137.407 104.780 117.231 1.00 62.84  ? 237 ARG A CZ  1 
ATOM 1040 N NH1 . ARG A 1 163 ? 138.456 104.073 117.618 1.00 67.64  ? 237 ARG A NH1 1 
ATOM 1041 N NH2 . ARG A 1 163 ? 137.111 105.907 117.870 1.00 65.28  ? 237 ARG A NH2 1 
ATOM 1042 N N   . SER A 1 164 ? 131.488 101.159 115.777 1.00 50.97  ? 238 SER A N   1 
ATOM 1043 C CA  . SER A 1 164 ? 130.226 100.879 115.113 1.00 49.02  ? 238 SER A CA  1 
ATOM 1044 C C   . SER A 1 164 ? 130.098 101.681 113.825 1.00 55.37  ? 238 SER A C   1 
ATOM 1045 O O   . SER A 1 164 ? 130.708 102.741 113.663 1.00 65.42  ? 238 SER A O   1 
ATOM 1046 C CB  . SER A 1 164 ? 129.054 101.196 116.039 1.00 56.78  ? 238 SER A CB  1 
ATOM 1047 O OG  . SER A 1 164 ? 129.138 100.450 117.240 1.00 60.81  ? 238 SER A OG  1 
ATOM 1048 N N   . ARG A 1 165 ? 129.288 101.163 112.904 1.00 49.25  ? 239 ARG A N   1 
ATOM 1049 C CA  . ARG A 1 165 ? 129.004 101.832 111.645 1.00 40.96  ? 239 ARG A CA  1 
ATOM 1050 C C   . ARG A 1 165 ? 127.512 101.763 111.353 1.00 48.04  ? 239 ARG A C   1 
ATOM 1051 O O   . ARG A 1 165 ? 126.801 100.885 111.845 1.00 55.08  ? 239 ARG A O   1 
ATOM 1052 C CB  . ARG A 1 165 ? 129.795 101.220 110.482 1.00 43.58  ? 239 ARG A CB  1 
ATOM 1053 C CG  . ARG A 1 165 ? 131.295 101.413 110.585 1.00 52.40  ? 239 ARG A CG  1 
ATOM 1054 C CD  . ARG A 1 165 ? 131.976 101.193 109.249 1.00 48.10  ? 239 ARG A CD  1 
ATOM 1055 N NE  . ARG A 1 165 ? 131.844 99.818  108.787 1.00 44.68  ? 239 ARG A NE  1 
ATOM 1056 C CZ  . ARG A 1 165 ? 132.342 99.363  107.647 1.00 55.25  ? 239 ARG A CZ  1 
ATOM 1057 N NH1 . ARG A 1 165 ? 133.012 100.151 106.822 1.00 59.08  ? 239 ARG A NH1 1 
ATOM 1058 N NH2 . ARG A 1 165 ? 132.164 98.086  107.326 1.00 57.81  ? 239 ARG A NH2 1 
ATOM 1059 N N   . LEU A 1 166 ? 127.046 102.708 110.543 1.00 54.99  ? 240 LEU A N   1 
ATOM 1060 C CA  . LEU A 1 166 ? 125.646 102.809 110.155 1.00 56.08  ? 240 LEU A CA  1 
ATOM 1061 C C   . LEU A 1 166 ? 125.482 102.390 108.703 1.00 56.18  ? 240 LEU A C   1 
ATOM 1062 O O   . LEU A 1 166 ? 126.256 102.817 107.840 1.00 57.28  ? 240 LEU A O   1 
ATOM 1063 C CB  . LEU A 1 166 ? 125.124 104.235 110.335 1.00 48.78  ? 240 LEU A CB  1 
ATOM 1064 C CG  . LEU A 1 166 ? 125.104 104.832 111.737 1.00 50.26  ? 240 LEU A CG  1 
ATOM 1065 C CD1 . LEU A 1 166 ? 124.657 106.278 111.680 1.00 53.67  ? 240 LEU A CD1 1 
ATOM 1066 C CD2 . LEU A 1 166 ? 124.203 104.023 112.653 1.00 52.62  ? 240 LEU A CD2 1 
ATOM 1067 N N   . LYS A 1 167 ? 124.477 101.562 108.435 1.00 52.96  ? 241 LYS A N   1 
ATOM 1068 C CA  . LYS A 1 167 ? 124.067 101.255 107.071 1.00 45.50  ? 241 LYS A CA  1 
ATOM 1069 C C   . LYS A 1 167 ? 122.863 102.132 106.747 1.00 50.59  ? 241 LYS A C   1 
ATOM 1070 O O   . LYS A 1 167 ? 121.859 102.116 107.468 1.00 60.13  ? 241 LYS A O   1 
ATOM 1071 C CB  . LYS A 1 167 ? 123.755 99.768  106.895 1.00 48.25  ? 241 LYS A CB  1 
ATOM 1072 C CG  . LYS A 1 167 ? 122.595 99.232  107.714 1.00 53.63  ? 241 LYS A CG  1 
ATOM 1073 C CD  . LYS A 1 167 ? 122.338 97.765  107.413 1.00 55.38  ? 241 LYS A CD  1 
ATOM 1074 C CE  . LYS A 1 167 ? 123.415 96.878  108.016 1.00 61.10  ? 241 LYS A CE  1 
ATOM 1075 N NZ  . LYS A 1 167 ? 123.108 95.431  107.845 1.00 60.41  ? 241 LYS A NZ  1 
ATOM 1076 N N   . VAL A 1 168 ? 122.977 102.925 105.689 1.00 43.97  ? 242 VAL A N   1 
ATOM 1077 C CA  . VAL A 1 168 ? 121.918 103.833 105.272 1.00 47.98  ? 242 VAL A CA  1 
ATOM 1078 C C   . VAL A 1 168 ? 121.456 103.434 103.879 1.00 54.61  ? 242 VAL A C   1 
ATOM 1079 O O   . VAL A 1 168 ? 122.276 103.147 102.999 1.00 55.27  ? 242 VAL A O   1 
ATOM 1080 C CB  . VAL A 1 168 ? 122.374 105.302 105.318 1.00 48.21  ? 242 VAL A CB  1 
ATOM 1081 C CG1 . VAL A 1 168 ? 122.688 105.704 106.748 1.00 51.11  ? 242 VAL A CG1 1 
ATOM 1082 C CG2 . VAL A 1 168 ? 123.590 105.512 104.451 1.00 55.19  ? 242 VAL A CG2 1 
ATOM 1083 N N   . ARG A 1 169 ? 120.141 103.387 103.692 1.00 55.50  ? 243 ARG A N   1 
ATOM 1084 C CA  . ARG A 1 169 ? 119.530 103.056 102.414 1.00 46.69  ? 243 ARG A CA  1 
ATOM 1085 C C   . ARG A 1 169 ? 118.721 104.256 101.952 1.00 51.45  ? 243 ARG A C   1 
ATOM 1086 O O   . ARG A 1 169 ? 117.826 104.714 102.670 1.00 59.90  ? 243 ARG A O   1 
ATOM 1087 C CB  . ARG A 1 169 ? 118.633 101.826 102.539 1.00 55.45  ? 243 ARG A CB  1 
ATOM 1088 C CG  . ARG A 1 169 ? 119.378 100.522 102.725 1.00 60.16  ? 243 ARG A CG  1 
ATOM 1089 C CD  . ARG A 1 169 ? 118.431 99.330  102.689 1.00 57.16  ? 243 ARG A CD  1 
ATOM 1090 N NE  . ARG A 1 169 ? 117.749 99.202  101.406 1.00 61.30  ? 243 ARG A NE  1 
ATOM 1091 C CZ  . ARG A 1 169 ? 116.501 99.587  101.176 1.00 62.10  ? 243 ARG A CZ  1 
ATOM 1092 N NH1 . ARG A 1 169 ? 115.759 100.130 102.127 1.00 59.92  ? 243 ARG A NH1 1 
ATOM 1093 N NH2 . ARG A 1 169 ? 115.985 99.422  99.962  1.00 61.85  ? 243 ARG A NH2 1 
ATOM 1094 N N   . VAL A 1 170 ? 119.029 104.760 100.764 1.00 46.41  ? 244 VAL A N   1 
ATOM 1095 C CA  . VAL A 1 170 ? 118.287 105.862 100.167 1.00 39.74  ? 244 VAL A CA  1 
ATOM 1096 C C   . VAL A 1 170 ? 117.376 105.278 99.100  1.00 47.17  ? 244 VAL A C   1 
ATOM 1097 O O   . VAL A 1 170 ? 117.850 104.766 98.079  1.00 57.61  ? 244 VAL A O   1 
ATOM 1098 C CB  . VAL A 1 170 ? 119.227 106.923 99.578  1.00 43.43  ? 244 VAL A CB  1 
ATOM 1099 C CG1 . VAL A 1 170 ? 118.426 108.075 99.002  1.00 48.93  ? 244 VAL A CG1 1 
ATOM 1100 C CG2 . VAL A 1 170 ? 120.192 107.420 100.637 1.00 49.94  ? 244 VAL A CG2 1 
ATOM 1101 N N   . VAL A 1 171 ? 116.071 105.349 99.335  1.00 56.99  ? 245 VAL A N   1 
ATOM 1102 C CA  . VAL A 1 171 ? 115.076 104.767 98.445  1.00 61.18  ? 245 VAL A CA  1 
ATOM 1103 C C   . VAL A 1 171 ? 114.521 105.866 97.556  1.00 65.90  ? 245 VAL A C   1 
ATOM 1104 O O   . VAL A 1 171 ? 114.026 106.887 98.049  1.00 65.18  ? 245 VAL A O   1 
ATOM 1105 C CB  . VAL A 1 171 ? 113.954 104.078 99.238  1.00 59.16  ? 245 VAL A CB  1 
ATOM 1106 C CG1 . VAL A 1 171 ? 112.932 103.473 98.289  1.00 59.85  ? 245 VAL A CG1 1 
ATOM 1107 C CG2 . VAL A 1 171 ? 114.534 103.013 100.153 1.00 56.64  ? 245 VAL A CG2 1 
ATOM 1108 N N   . LYS A 1 172 ? 114.600 105.658 96.246  1.00 64.18  ? 246 LYS A N   1 
ATOM 1109 C CA  . LYS A 1 172 ? 114.140 106.626 95.265  1.00 52.64  ? 246 LYS A CA  1 
ATOM 1110 C C   . LYS A 1 172 ? 112.797 106.185 94.699  1.00 57.75  ? 246 LYS A C   1 
ATOM 1111 O O   . LYS A 1 172 ? 112.577 104.996 94.452  1.00 62.02  ? 246 LYS A O   1 
ATOM 1112 C CB  . LYS A 1 172 ? 115.159 106.777 94.138  1.00 53.13  ? 246 LYS A CB  1 
ATOM 1113 C CG  . LYS A 1 172 ? 116.427 107.493 94.550  1.00 57.18  ? 246 LYS A CG  1 
ATOM 1114 C CD  . LYS A 1 172 ? 116.168 108.955 94.830  1.00 54.13  ? 246 LYS A CD  1 
ATOM 1115 C CE  . LYS A 1 172 ? 117.466 109.695 95.087  1.00 57.12  ? 246 LYS A CE  1 
ATOM 1116 N NZ  . LYS A 1 172 ? 117.237 111.147 95.310  1.00 62.06  ? 246 LYS A NZ  1 
ATOM 1117 N N   . GLU A 1 173 ? 111.903 107.148 94.501  1.00 78.42  ? 247 GLU A N   1 
ATOM 1118 C CA  . GLU A 1 173 ? 110.568 106.861 93.987  1.00 85.14  ? 247 GLU A CA  1 
ATOM 1119 C C   . GLU A 1 173 ? 110.624 106.340 92.554  1.00 89.19  ? 247 GLU A C   1 
ATOM 1120 O O   . GLU A 1 173 ? 109.913 105.400 92.197  1.00 91.90  ? 247 GLU A O   1 
ATOM 1121 C CB  . GLU A 1 173 ? 109.685 108.111 94.068  1.00 83.60  ? 247 GLU A CB  1 
ATOM 1122 C CG  . GLU A 1 173 ? 110.189 109.302 93.262  1.00 87.50  ? 247 GLU A CG  1 
ATOM 1123 C CD  . GLU A 1 173 ? 109.716 109.283 91.820  1.00 94.09  ? 247 GLU A CD  1 
ATOM 1124 O OE1 . GLU A 1 173 ? 108.720 108.588 91.529  1.00 90.87  ? 247 GLU A OE1 1 
ATOM 1125 O OE2 . GLU A 1 173 ? 110.342 109.962 90.979  1.00 99.08  ? 247 GLU A OE2 1 
ATOM 1126 N N   . ALA A 1 203 ? 118.103 100.407 97.480  1.00 84.17  ? 277 ALA A N   1 
ATOM 1127 C CA  . ALA A 1 203 ? 118.506 100.694 96.109  1.00 86.92  ? 277 ALA A CA  1 
ATOM 1128 C C   . ALA A 1 203 ? 119.976 101.094 96.045  1.00 85.62  ? 277 ALA A C   1 
ATOM 1129 O O   . ALA A 1 203 ? 120.687 100.732 95.108  1.00 83.58  ? 277 ALA A O   1 
ATOM 1130 C CB  . ALA A 1 203 ? 117.631 101.789 95.517  1.00 81.46  ? 277 ALA A CB  1 
ATOM 1131 N N   . MET A 1 204 ? 120.427 101.844 97.051  1.00 70.00  ? 278 MET A N   1 
ATOM 1132 C CA  . MET A 1 204 ? 121.815 102.299 97.103  1.00 65.80  ? 278 MET A CA  1 
ATOM 1133 C C   . MET A 1 204 ? 122.227 102.366 98.571  1.00 71.84  ? 278 MET A C   1 
ATOM 1134 O O   . MET A 1 204 ? 121.958 103.362 99.248  1.00 74.58  ? 278 MET A O   1 
ATOM 1135 C CB  . MET A 1 204 ? 121.975 103.646 96.414  1.00 65.20  ? 278 MET A CB  1 
ATOM 1136 C CG  . MET A 1 204 ? 123.416 104.029 96.105  1.00 70.11  ? 278 MET A CG  1 
ATOM 1137 S SD  . MET A 1 204 ? 124.174 103.011 94.822  1.00 82.73  ? 278 MET A SD  1 
ATOM 1138 C CE  . MET A 1 204 ? 125.148 101.873 95.807  1.00 70.02  ? 278 MET A CE  1 
ATOM 1139 N N   . GLN A 1 205 ? 122.876 101.309 99.050  1.00 60.25  ? 279 GLN A N   1 
ATOM 1140 C CA  . GLN A 1 205 ? 123.333 101.259 100.428 1.00 49.34  ? 279 GLN A CA  1 
ATOM 1141 C C   . GLN A 1 205 ? 124.624 102.047 100.600 1.00 53.60  ? 279 GLN A C   1 
ATOM 1142 O O   . GLN A 1 205 ? 125.344 102.326 99.638  1.00 58.92  ? 279 GLN A O   1 
ATOM 1143 C CB  . GLN A 1 205 ? 123.561 99.815  100.873 1.00 48.01  ? 279 GLN A CB  1 
ATOM 1144 C CG  . GLN A 1 205 ? 122.296 99.026  101.122 1.00 52.19  ? 279 GLN A CG  1 
ATOM 1145 C CD  . GLN A 1 205 ? 122.565 97.727  101.849 1.00 57.83  ? 279 GLN A CD  1 
ATOM 1146 O OE1 . GLN A 1 205 ? 123.714 97.379  102.118 1.00 59.84  ? 279 GLN A OE1 1 
ATOM 1147 N NE2 . GLN A 1 205 ? 121.503 96.999  102.174 1.00 56.70  ? 279 GLN A NE2 1 
ATOM 1148 N N   . TYR A 1 206 ? 124.911 102.405 101.848 1.00 51.92  ? 280 TYR A N   1 
ATOM 1149 C CA  . TYR A 1 206 ? 126.183 103.001 102.221 1.00 47.45  ? 280 TYR A CA  1 
ATOM 1150 C C   . TYR A 1 206 ? 126.546 102.536 103.622 1.00 57.49  ? 280 TYR A C   1 
ATOM 1151 O O   . TYR A 1 206 ? 125.673 102.194 104.424 1.00 65.69  ? 280 TYR A O   1 
ATOM 1152 C CB  . TYR A 1 206 ? 126.143 104.531 102.192 1.00 46.07  ? 280 TYR A CB  1 
ATOM 1153 C CG  . TYR A 1 206 ? 125.770 105.137 100.863 1.00 50.46  ? 280 TYR A CG  1 
ATOM 1154 C CD1 . TYR A 1 206 ? 126.711 105.284 99.856  1.00 56.51  ? 280 TYR A CD1 1 
ATOM 1155 C CD2 . TYR A 1 206 ? 124.479 105.578 100.621 1.00 54.81  ? 280 TYR A CD2 1 
ATOM 1156 C CE1 . TYR A 1 206 ? 126.375 105.848 98.640  1.00 55.61  ? 280 TYR A CE1 1 
ATOM 1157 C CE2 . TYR A 1 206 ? 124.131 106.141 99.412  1.00 59.16  ? 280 TYR A CE2 1 
ATOM 1158 C CZ  . TYR A 1 206 ? 125.082 106.274 98.425  1.00 58.82  ? 280 TYR A CZ  1 
ATOM 1159 O OH  . TYR A 1 206 ? 124.735 106.836 97.218  1.00 57.32  ? 280 TYR A OH  1 
ATOM 1160 N N   . GLN A 1 207 ? 127.842 102.522 103.910 1.00 50.86  ? 281 GLN A N   1 
ATOM 1161 C CA  . GLN A 1 207 ? 128.349 102.267 105.251 1.00 46.25  ? 281 GLN A CA  1 
ATOM 1162 C C   . GLN A 1 207 ? 129.037 103.534 105.739 1.00 44.45  ? 281 GLN A C   1 
ATOM 1163 O O   . GLN A 1 207 ? 129.959 104.033 105.087 1.00 55.00  ? 281 GLN A O   1 
ATOM 1164 C CB  . GLN A 1 207 ? 129.311 101.081 105.262 1.00 48.38  ? 281 GLN A CB  1 
ATOM 1165 C CG  . GLN A 1 207 ? 128.683 99.775  104.811 1.00 49.63  ? 281 GLN A CG  1 
ATOM 1166 C CD  . GLN A 1 207 ? 127.661 99.244  105.792 1.00 58.58  ? 281 GLN A CD  1 
ATOM 1167 O OE1 . GLN A 1 207 ? 127.655 99.619  106.964 1.00 58.33  ? 281 GLN A OE1 1 
ATOM 1168 N NE2 . GLN A 1 207 ? 126.789 98.364  105.317 1.00 57.99  ? 281 GLN A NE2 1 
ATOM 1169 N N   . VAL A 1 208 ? 128.587 104.048 106.876 1.00 45.52  ? 282 VAL A N   1 
ATOM 1170 C CA  . VAL A 1 208 ? 129.006 105.347 107.385 1.00 45.30  ? 282 VAL A CA  1 
ATOM 1171 C C   . VAL A 1 208 ? 129.643 105.155 108.752 1.00 50.35  ? 282 VAL A C   1 
ATOM 1172 O O   . VAL A 1 208 ? 129.060 104.508 109.629 1.00 59.89  ? 282 VAL A O   1 
ATOM 1173 C CB  . VAL A 1 208 ? 127.821 106.323 107.467 1.00 53.35  ? 282 VAL A CB  1 
ATOM 1174 C CG1 . VAL A 1 208 ? 128.249 107.612 108.119 1.00 54.50  ? 282 VAL A CG1 1 
ATOM 1175 C CG2 . VAL A 1 208 ? 127.257 106.585 106.080 1.00 57.21  ? 282 VAL A CG2 1 
ATOM 1176 N N   . LEU A 1 209 ? 130.835 105.721 108.931 1.00 50.31  ? 283 LEU A N   1 
ATOM 1177 C CA  . LEU A 1 209 ? 131.574 105.579 110.179 1.00 48.07  ? 283 LEU A CA  1 
ATOM 1178 C C   . LEU A 1 209 ? 131.348 106.751 111.127 1.00 45.81  ? 283 LEU A C   1 
ATOM 1179 O O   . LEU A 1 209 ? 131.104 106.543 112.318 1.00 54.63  ? 283 LEU A O   1 
ATOM 1180 C CB  . LEU A 1 209 ? 133.068 105.425 109.890 1.00 52.25  ? 283 LEU A CB  1 
ATOM 1181 C CG  . LEU A 1 209 ? 133.968 105.235 111.110 1.00 48.33  ? 283 LEU A CG  1 
ATOM 1182 C CD1 . LEU A 1 209 ? 133.564 103.996 111.885 1.00 49.19  ? 283 LEU A CD1 1 
ATOM 1183 C CD2 . LEU A 1 209 ? 135.422 105.159 110.689 1.00 55.10  ? 283 LEU A CD2 1 
ATOM 1184 N N   . ASN A 1 210 ? 131.430 107.983 110.626 1.00 51.05  ? 284 ASN A N   1 
ATOM 1185 C CA  . ASN A 1 210 ? 131.353 109.155 111.508 1.00 59.51  ? 284 ASN A CA  1 
ATOM 1186 C C   . ASN A 1 210 ? 129.931 109.703 111.614 1.00 59.93  ? 284 ASN A C   1 
ATOM 1187 O O   . ASN A 1 210 ? 129.343 109.702 112.699 1.00 54.95  ? 284 ASN A O   1 
ATOM 1188 C CB  . ASN A 1 210 ? 132.337 110.229 111.040 1.00 53.42  ? 284 ASN A CB  1 
ATOM 1189 C CG  . ASN A 1 210 ? 133.770 109.905 111.405 1.00 60.32  ? 284 ASN A CG  1 
ATOM 1190 O OD1 . ASN A 1 210 ? 134.704 110.295 110.708 1.00 64.16  ? 284 ASN A OD1 1 
ATOM 1191 N ND2 . ASN A 1 210 ? 133.951 109.185 112.506 1.00 63.71  ? 284 ASN A ND2 1 
ATOM 1192 N N   . GLU A 1 211 ? 129.360 110.164 110.501 1.00 43.80  ? 285 GLU A N   1 
ATOM 1193 C CA  . GLU A 1 211 ? 127.984 110.643 110.546 1.00 38.48  ? 285 GLU A CA  1 
ATOM 1194 C C   . GLU A 1 211 ? 127.393 110.696 109.147 1.00 43.14  ? 285 GLU A C   1 
ATOM 1195 O O   . GLU A 1 211 ? 128.110 110.769 108.146 1.00 47.93  ? 285 GLU A O   1 
ATOM 1196 C CB  . GLU A 1 211 ? 127.866 112.035 111.182 1.00 46.57  ? 285 GLU A CB  1 
ATOM 1197 C CG  . GLU A 1 211 ? 128.376 113.187 110.325 1.00 54.75  ? 285 GLU A CG  1 
ATOM 1198 C CD  . GLU A 1 211 ? 129.850 113.466 110.498 1.00 56.63  ? 285 GLU A CD  1 
ATOM 1199 O OE1 . GLU A 1 211 ? 130.555 112.617 111.068 1.00 62.63  ? 285 GLU A OE1 1 
ATOM 1200 O OE2 . GLU A 1 211 ? 130.305 114.543 110.061 1.00 58.51  ? 285 GLU A OE2 1 
ATOM 1201 N N   . VAL A 1 212 ? 126.063 110.677 109.103 1.00 37.90  ? 286 VAL A N   1 
ATOM 1202 C CA  . VAL A 1 212 ? 125.288 111.041 107.923 1.00 26.07  ? 286 VAL A CA  1 
ATOM 1203 C C   . VAL A 1 212 ? 124.546 112.334 108.239 1.00 39.81  ? 286 VAL A C   1 
ATOM 1204 O O   . VAL A 1 212 ? 123.939 112.466 109.309 1.00 47.32  ? 286 VAL A O   1 
ATOM 1205 C CB  . VAL A 1 212 ? 124.325 109.916 107.500 1.00 25.77  ? 286 VAL A CB  1 
ATOM 1206 C CG1 . VAL A 1 212 ? 123.297 109.630 108.579 1.00 35.38  ? 286 VAL A CG1 1 
ATOM 1207 C CG2 . VAL A 1 212 ? 123.633 110.279 106.202 1.00 37.87  ? 286 VAL A CG2 1 
ATOM 1208 N N   . VAL A 1 213 ? 124.629 113.302 107.332 1.00 35.66  ? 287 VAL A N   1 
ATOM 1209 C CA  . VAL A 1 213 ? 124.075 114.633 107.544 1.00 25.05  ? 287 VAL A CA  1 
ATOM 1210 C C   . VAL A 1 213 ? 122.985 114.879 106.515 1.00 39.39  ? 287 VAL A C   1 
ATOM 1211 O O   . VAL A 1 213 ? 123.195 114.661 105.317 1.00 42.95  ? 287 VAL A O   1 
ATOM 1212 C CB  . VAL A 1 213 ? 125.158 115.722 107.453 1.00 31.25  ? 287 VAL A CB  1 
ATOM 1213 C CG1 . VAL A 1 213 ? 124.559 117.086 107.739 1.00 41.19  ? 287 VAL A CG1 1 
ATOM 1214 C CG2 . VAL A 1 213 ? 126.279 115.430 108.421 1.00 33.67  ? 287 VAL A CG2 1 
ATOM 1215 N N   . ILE A 1 214 ? 121.826 115.330 106.983 1.00 46.33  ? 288 ILE A N   1 
ATOM 1216 C CA  . ILE A 1 214 ? 120.718 115.725 106.122 1.00 37.95  ? 288 ILE A CA  1 
ATOM 1217 C C   . ILE A 1 214 ? 120.474 117.200 106.403 1.00 39.97  ? 288 ILE A C   1 
ATOM 1218 O O   . ILE A 1 214 ? 119.833 117.551 107.400 1.00 51.93  ? 288 ILE A O   1 
ATOM 1219 C CB  . ILE A 1 214 ? 119.455 114.894 106.369 1.00 39.53  ? 288 ILE A CB  1 
ATOM 1220 C CG1 . ILE A 1 214 ? 119.702 113.418 106.056 1.00 49.55  ? 288 ILE A CG1 1 
ATOM 1221 C CG2 . ILE A 1 214 ? 118.306 115.420 105.533 1.00 44.76  ? 288 ILE A CG2 1 
ATOM 1222 C CD1 . ILE A 1 214 ? 120.189 112.605 107.237 1.00 51.65  ? 288 ILE A CD1 1 
ATOM 1223 N N   . ASP A 1 215 ? 120.978 118.071 105.533 1.00 47.62  ? 289 ASP A N   1 
ATOM 1224 C CA  . ASP A 1 215 ? 120.930 119.503 105.772 1.00 44.32  ? 289 ASP A CA  1 
ATOM 1225 C C   . ASP A 1 215 ? 120.574 120.227 104.484 1.00 54.92  ? 289 ASP A C   1 
ATOM 1226 O O   . ASP A 1 215 ? 120.616 119.660 103.390 1.00 61.97  ? 289 ASP A O   1 
ATOM 1227 C CB  . ASP A 1 215 ? 122.261 120.029 106.318 1.00 43.95  ? 289 ASP A CB  1 
ATOM 1228 C CG  . ASP A 1 215 ? 123.402 119.847 105.341 1.00 61.70  ? 289 ASP A CG  1 
ATOM 1229 O OD1 . ASP A 1 215 ? 123.377 118.864 104.570 1.00 66.51  ? 289 ASP A OD1 1 
ATOM 1230 O OD2 . ASP A 1 215 ? 124.326 120.687 105.343 1.00 64.71  ? 289 ASP A OD2 1 
ATOM 1231 N N   . ARG A 1 216 ? 120.219 121.501 104.630 1.00 75.80  ? 290 ARG A N   1 
ATOM 1232 C CA  . ARG A 1 216 ? 119.915 122.350 103.487 1.00 74.51  ? 290 ARG A CA  1 
ATOM 1233 C C   . ARG A 1 216 ? 121.201 122.653 102.731 1.00 73.50  ? 290 ARG A C   1 
ATOM 1234 O O   . ARG A 1 216 ? 122.168 123.157 103.314 1.00 80.97  ? 290 ARG A O   1 
ATOM 1235 C CB  . ARG A 1 216 ? 119.245 123.642 103.944 1.00 74.85  ? 290 ARG A CB  1 
ATOM 1236 C CG  . ARG A 1 216 ? 119.778 124.185 105.258 1.00 76.77  ? 290 ARG A CG  1 
ATOM 1237 C CD  . ARG A 1 216 ? 119.127 125.511 105.609 1.00 79.06  ? 290 ARG A CD  1 
ATOM 1238 N NE  . ARG A 1 216 ? 119.635 126.603 104.786 1.00 85.24  ? 290 ARG A NE  1 
ATOM 1239 C CZ  . ARG A 1 216 ? 120.678 127.357 105.104 1.00 82.69  ? 290 ARG A CZ  1 
ATOM 1240 N NH1 . ARG A 1 216 ? 121.355 127.165 106.224 1.00 78.44  ? 290 ARG A NH1 1 
ATOM 1241 N NH2 . ARG A 1 216 ? 121.052 128.330 104.276 1.00 80.61  ? 290 ARG A NH2 1 
ATOM 1242 N N   . GLY A 1 217 ? 121.213 122.352 101.438 1.00 68.10  ? 291 GLY A N   1 
ATOM 1243 C CA  . GLY A 1 217 ? 122.361 122.618 100.609 1.00 74.49  ? 291 GLY A CA  1 
ATOM 1244 C C   . GLY A 1 217 ? 122.364 124.066 100.177 1.00 76.63  ? 291 GLY A C   1 
ATOM 1245 O O   . GLY A 1 217 ? 122.225 124.979 100.997 1.00 72.18  ? 291 GLY A O   1 
ATOM 1246 N N   . PRO A 1 218 ? 122.521 124.312 98.881  1.00 71.65  ? 292 PRO A N   1 
ATOM 1247 C CA  . PRO A 1 218 ? 122.379 125.687 98.394  1.00 68.86  ? 292 PRO A CA  1 
ATOM 1248 C C   . PRO A 1 218 ? 120.929 126.126 98.476  1.00 66.84  ? 292 PRO A C   1 
ATOM 1249 O O   . PRO A 1 218 ? 120.101 125.735 97.648  1.00 69.00  ? 292 PRO A O   1 
ATOM 1250 C CB  . PRO A 1 218 ? 122.874 125.603 96.945  1.00 64.83  ? 292 PRO A CB  1 
ATOM 1251 C CG  . PRO A 1 218 ? 122.675 124.173 96.561  1.00 63.56  ? 292 PRO A CG  1 
ATOM 1252 C CD  . PRO A 1 218 ? 122.886 123.370 97.810  1.00 62.68  ? 292 PRO A CD  1 
ATOM 1253 N N   . SER A 1 219 ? 120.621 126.950 99.470  1.00 69.35  ? 293 SER A N   1 
ATOM 1254 C CA  . SER A 1 219 ? 119.250 127.339 99.779  1.00 74.29  ? 293 SER A CA  1 
ATOM 1255 C C   . SER A 1 219 ? 119.299 128.430 100.839 1.00 77.27  ? 293 SER A C   1 
ATOM 1256 O O   . SER A 1 219 ? 120.367 128.782 101.349 1.00 79.30  ? 293 SER A O   1 
ATOM 1257 C CB  . SER A 1 219 ? 118.418 126.148 100.258 1.00 75.22  ? 293 SER A CB  1 
ATOM 1258 O OG  . SER A 1 219 ? 117.117 126.559 100.642 1.00 70.55  ? 293 SER A OG  1 
ATOM 1259 N N   . SER A 1 220 ? 118.136 128.962 101.161 1.00 84.61  ? 294 SER A N   1 
ATOM 1260 C CA  . SER A 1 220 ? 117.987 129.982 102.193 1.00 86.13  ? 294 SER A CA  1 
ATOM 1261 C C   . SER A 1 220 ? 116.937 129.621 103.232 1.00 84.76  ? 294 SER A C   1 
ATOM 1262 O O   . SER A 1 220 ? 117.095 129.972 104.403 1.00 86.96  ? 294 SER A O   1 
ATOM 1263 C CB  . SER A 1 220 ? 117.642 131.333 101.545 1.00 86.30  ? 294 SER A CB  1 
ATOM 1264 O OG  . SER A 1 220 ? 118.653 131.735 100.637 1.00 87.65  ? 294 SER A OG  1 
ATOM 1265 N N   . TYR A 1 221 ? 115.871 128.933 102.832 1.00 94.69  ? 295 TYR A N   1 
ATOM 1266 C CA  . TYR A 1 221 ? 114.787 128.615 103.749 1.00 96.28  ? 295 TYR A CA  1 
ATOM 1267 C C   . TYR A 1 221 ? 115.211 127.546 104.750 1.00 90.89  ? 295 TYR A C   1 
ATOM 1268 O O   . TYR A 1 221 ? 116.066 126.701 104.470 1.00 87.19  ? 295 TYR A O   1 
ATOM 1269 C CB  . TYR A 1 221 ? 113.558 128.140 102.975 1.00 97.34  ? 295 TYR A CB  1 
ATOM 1270 C CG  . TYR A 1 221 ? 112.839 129.240 102.231 1.00 104.68 ? 295 TYR A CG  1 
ATOM 1271 C CD1 . TYR A 1 221 ? 113.279 129.663 100.983 1.00 105.35 ? 295 TYR A CD1 1 
ATOM 1272 C CD2 . TYR A 1 221 ? 111.719 129.856 102.773 1.00 104.42 ? 295 TYR A CD2 1 
ATOM 1273 C CE1 . TYR A 1 221 ? 112.626 130.668 100.297 1.00 108.57 ? 295 TYR A CE1 1 
ATOM 1274 C CE2 . TYR A 1 221 ? 111.059 130.863 102.094 1.00 107.43 ? 295 TYR A CE2 1 
ATOM 1275 C CZ  . TYR A 1 221 ? 111.517 131.265 100.857 1.00 110.55 ? 295 TYR A CZ  1 
ATOM 1276 O OH  . TYR A 1 221 ? 110.863 132.266 100.177 1.00 114.55 ? 295 TYR A OH  1 
ATOM 1277 N N   . LEU A 1 222 ? 114.602 127.595 105.931 1.00 80.24  ? 296 LEU A N   1 
ATOM 1278 C CA  . LEU A 1 222 ? 114.843 126.578 106.943 1.00 82.10  ? 296 LEU A CA  1 
ATOM 1279 C C   . LEU A 1 222 ? 114.260 125.241 106.502 1.00 83.58  ? 296 LEU A C   1 
ATOM 1280 O O   . LEU A 1 222 ? 113.197 125.174 105.880 1.00 87.05  ? 296 LEU A O   1 
ATOM 1281 C CB  . LEU A 1 222 ? 114.234 127.000 108.278 1.00 80.82  ? 296 LEU A CB  1 
ATOM 1282 C CG  . LEU A 1 222 ? 114.742 128.316 108.866 1.00 81.24  ? 296 LEU A CG  1 
ATOM 1283 C CD1 . LEU A 1 222 ? 114.011 128.640 110.160 1.00 81.47  ? 296 LEU A CD1 1 
ATOM 1284 C CD2 . LEU A 1 222 ? 116.246 128.261 109.092 1.00 80.19  ? 296 LEU A CD2 1 
ATOM 1285 N N   . SER A 1 223 ? 114.972 124.167 106.829 1.00 81.57  ? 297 SER A N   1 
ATOM 1286 C CA  . SER A 1 223 ? 114.543 122.832 106.444 1.00 81.78  ? 297 SER A CA  1 
ATOM 1287 C C   . SER A 1 223 ? 113.377 122.365 107.307 1.00 84.63  ? 297 SER A C   1 
ATOM 1288 O O   . SER A 1 223 ? 113.216 122.785 108.456 1.00 81.51  ? 297 SER A O   1 
ATOM 1289 C CB  . SER A 1 223 ? 115.703 121.843 106.556 1.00 81.02  ? 297 SER A CB  1 
ATOM 1290 O OG  . SER A 1 223 ? 116.777 122.218 105.713 1.00 79.92  ? 297 SER A OG  1 
ATOM 1291 N N   . ASN A 1 224 ? 112.555 121.483 106.734 1.00 77.64  ? 298 ASN A N   1 
ATOM 1292 C CA  . ASN A 1 224 ? 111.430 120.862 107.441 1.00 71.23  ? 298 ASN A CA  1 
ATOM 1293 C C   . ASN A 1 224 ? 111.410 119.386 107.052 1.00 72.81  ? 298 ASN A C   1 
ATOM 1294 O O   . ASN A 1 224 ? 110.805 119.006 106.047 1.00 74.78  ? 298 ASN A O   1 
ATOM 1295 C CB  . ASN A 1 224 ? 110.115 121.551 107.111 1.00 67.69  ? 298 ASN A CB  1 
ATOM 1296 C CG  . ASN A 1 224 ? 109.851 122.750 107.990 1.00 73.71  ? 298 ASN A CG  1 
ATOM 1297 O OD1 . ASN A 1 224 ? 109.112 122.665 108.971 1.00 73.23  ? 298 ASN A OD1 1 
ATOM 1298 N ND2 . ASN A 1 224 ? 110.458 123.880 107.647 1.00 74.78  ? 298 ASN A ND2 1 
ATOM 1299 N N   . VAL A 1 225 ? 112.072 118.559 107.857 1.00 62.68  ? 299 VAL A N   1 
ATOM 1300 C CA  . VAL A 1 225 ? 112.212 117.136 107.582 1.00 58.97  ? 299 VAL A CA  1 
ATOM 1301 C C   . VAL A 1 225 ? 111.748 116.352 108.803 1.00 59.94  ? 299 VAL A C   1 
ATOM 1302 O O   . VAL A 1 225 ? 111.981 116.763 109.945 1.00 57.69  ? 299 VAL A O   1 
ATOM 1303 C CB  . VAL A 1 225 ? 113.664 116.779 107.195 1.00 56.91  ? 299 VAL A CB  1 
ATOM 1304 C CG1 . VAL A 1 225 ? 114.613 117.017 108.351 1.00 62.31  ? 299 VAL A CG1 1 
ATOM 1305 C CG2 . VAL A 1 225 ? 113.756 115.351 106.704 1.00 57.77  ? 299 VAL A CG2 1 
ATOM 1306 N N   . ASP A 1 226 ? 111.066 115.237 108.560 1.00 65.48  ? 300 ASP A N   1 
ATOM 1307 C CA  . ASP A 1 226 ? 110.504 114.406 109.613 1.00 61.77  ? 300 ASP A CA  1 
ATOM 1308 C C   . ASP A 1 226 ? 111.433 113.243 109.936 1.00 63.68  ? 300 ASP A C   1 
ATOM 1309 O O   . ASP A 1 226 ? 112.049 112.648 109.049 1.00 71.47  ? 300 ASP A O   1 
ATOM 1310 C CB  . ASP A 1 226 ? 109.130 113.869 109.212 1.00 68.45  ? 300 ASP A CB  1 
ATOM 1311 C CG  . ASP A 1 226 ? 108.073 114.954 109.158 1.00 74.34  ? 300 ASP A CG  1 
ATOM 1312 O OD1 . ASP A 1 226 ? 108.401 116.119 109.462 1.00 72.79  ? 300 ASP A OD1 1 
ATOM 1313 O OD2 . ASP A 1 226 ? 106.913 114.642 108.814 1.00 74.40  ? 300 ASP A OD2 1 
ATOM 1314 N N   . VAL A 1 227 ? 111.523 112.923 111.224 1.00 55.35  ? 301 VAL A N   1 
ATOM 1315 C CA  . VAL A 1 227 ? 112.367 111.843 111.721 1.00 51.95  ? 301 VAL A CA  1 
ATOM 1316 C C   . VAL A 1 227 ? 111.461 110.776 112.314 1.00 55.57  ? 301 VAL A C   1 
ATOM 1317 O O   . VAL A 1 227 ? 110.663 111.062 113.215 1.00 67.16  ? 301 VAL A O   1 
ATOM 1318 C CB  . VAL A 1 227 ? 113.377 112.340 112.765 1.00 51.29  ? 301 VAL A CB  1 
ATOM 1319 C CG1 . VAL A 1 227 ? 114.175 111.177 113.322 1.00 51.12  ? 301 VAL A CG1 1 
ATOM 1320 C CG2 . VAL A 1 227 ? 114.297 113.383 112.159 1.00 56.80  ? 301 VAL A CG2 1 
ATOM 1321 N N   . TYR A 1 228 ? 111.586 109.551 111.815 1.00 56.90  ? 302 TYR A N   1 
ATOM 1322 C CA  . TYR A 1 228 ? 110.803 108.420 112.289 1.00 56.32  ? 302 TYR A CA  1 
ATOM 1323 C C   . TYR A 1 228 ? 111.704 107.455 113.044 1.00 59.38  ? 302 TYR A C   1 
ATOM 1324 O O   . TYR A 1 228 ? 112.848 107.217 112.644 1.00 63.40  ? 302 TYR A O   1 
ATOM 1325 C CB  . TYR A 1 228 ? 110.128 107.683 111.130 1.00 59.67  ? 302 TYR A CB  1 
ATOM 1326 C CG  . TYR A 1 228 ? 109.019 108.448 110.450 1.00 62.58  ? 302 TYR A CG  1 
ATOM 1327 C CD1 . TYR A 1 228 ? 109.291 109.572 109.686 1.00 61.76  ? 302 TYR A CD1 1 
ATOM 1328 C CD2 . TYR A 1 228 ? 107.701 108.037 110.560 1.00 67.13  ? 302 TYR A CD2 1 
ATOM 1329 C CE1 . TYR A 1 228 ? 108.282 110.269 109.058 1.00 58.07  ? 302 TYR A CE1 1 
ATOM 1330 C CE2 . TYR A 1 228 ? 106.684 108.729 109.936 1.00 66.88  ? 302 TYR A CE2 1 
ATOM 1331 C CZ  . TYR A 1 228 ? 106.981 109.843 109.185 1.00 61.62  ? 302 TYR A CZ  1 
ATOM 1332 O OH  . TYR A 1 228 ? 105.970 110.538 108.562 1.00 64.38  ? 302 TYR A OH  1 
ATOM 1333 N N   . LEU A 1 229 ? 111.186 106.906 114.138 1.00 56.00  ? 303 LEU A N   1 
ATOM 1334 C CA  . LEU A 1 229 ? 111.895 105.903 114.929 1.00 56.64  ? 303 LEU A CA  1 
ATOM 1335 C C   . LEU A 1 229 ? 110.972 104.697 115.073 1.00 57.88  ? 303 LEU A C   1 
ATOM 1336 O O   . LEU A 1 229 ? 110.076 104.696 115.921 1.00 59.81  ? 303 LEU A O   1 
ATOM 1337 C CB  . LEU A 1 229 ? 112.304 106.459 116.288 1.00 56.91  ? 303 LEU A CB  1 
ATOM 1338 C CG  . LEU A 1 229 ? 113.579 105.866 116.885 1.00 56.31  ? 303 LEU A CG  1 
ATOM 1339 C CD1 . LEU A 1 229 ? 114.779 106.234 116.039 1.00 58.97  ? 303 LEU A CD1 1 
ATOM 1340 C CD2 . LEU A 1 229 ? 113.779 106.315 118.313 1.00 52.77  ? 303 LEU A CD2 1 
ATOM 1341 N N   . ASP A 1 230 ? 111.196 103.679 114.242 1.00 65.48  ? 304 ASP A N   1 
ATOM 1342 C CA  . ASP A 1 230 ? 110.366 102.473 114.221 1.00 64.49  ? 304 ASP A CA  1 
ATOM 1343 C C   . ASP A 1 230 ? 108.904 102.807 113.927 1.00 64.94  ? 304 ASP A C   1 
ATOM 1344 O O   . ASP A 1 230 ? 107.988 102.269 114.550 1.00 66.47  ? 304 ASP A O   1 
ATOM 1345 C CB  . ASP A 1 230 ? 110.493 101.692 115.531 1.00 65.71  ? 304 ASP A CB  1 
ATOM 1346 C CG  . ASP A 1 230 ? 111.872 101.092 115.719 1.00 69.79  ? 304 ASP A CG  1 
ATOM 1347 O OD1 . ASP A 1 230 ? 112.712 101.234 114.806 1.00 71.92  ? 304 ASP A OD1 1 
ATOM 1348 O OD2 . ASP A 1 230 ? 112.117 100.481 116.780 1.00 68.22  ? 304 ASP A OD2 1 
ATOM 1349 N N   . GLY A 1 231 ? 108.684 103.702 112.965 1.00 70.89  ? 305 GLY A N   1 
ATOM 1350 C CA  . GLY A 1 231 ? 107.334 104.094 112.605 1.00 71.89  ? 305 GLY A CA  1 
ATOM 1351 C C   . GLY A 1 231 ? 106.609 104.884 113.667 1.00 71.58  ? 305 GLY A C   1 
ATOM 1352 O O   . GLY A 1 231 ? 105.377 104.879 113.702 1.00 77.55  ? 305 GLY A O   1 
ATOM 1353 N N   . HIS A 1 232 ? 107.347 105.571 114.534 1.00 68.61  ? 306 HIS A N   1 
ATOM 1354 C CA  . HIS A 1 232 ? 106.807 106.240 115.713 1.00 72.64  ? 306 HIS A CA  1 
ATOM 1355 C C   . HIS A 1 232 ? 107.302 107.683 115.747 1.00 73.11  ? 306 HIS A C   1 
ATOM 1356 O O   . HIS A 1 232 ? 107.955 108.102 116.701 1.00 79.13  ? 306 HIS A O   1 
ATOM 1357 C CB  . HIS A 1 232 ? 107.161 105.504 117.004 1.00 73.77  ? 306 HIS A CB  1 
ATOM 1358 C CG  . HIS A 1 232 ? 106.475 104.183 117.152 1.00 75.89  ? 306 HIS A CG  1 
ATOM 1359 N ND1 . HIS A 1 232 ? 106.955 103.181 117.967 1.00 76.45  ? 306 HIS A ND1 1 
ATOM 1360 C CD2 . HIS A 1 232 ? 105.338 103.703 116.595 1.00 75.07  ? 306 HIS A CD2 1 
ATOM 1361 C CE1 . HIS A 1 232 ? 106.146 102.138 117.902 1.00 76.74  ? 306 HIS A CE1 1 
ATOM 1362 N NE2 . HIS A 1 232 ? 105.157 102.429 117.076 1.00 79.08  ? 306 HIS A NE2 1 
ATOM 1363 N N   . LEU A 1 233 ? 107.011 108.426 114.675 1.00 55.35  ? 307 LEU A N   1 
ATOM 1364 C CA  . LEU A 1 233 ? 107.571 109.748 114.408 1.00 57.02  ? 307 LEU A CA  1 
ATOM 1365 C C   . LEU A 1 233 ? 107.775 110.542 115.686 1.00 62.55  ? 307 LEU A C   1 
ATOM 1366 O O   . LEU A 1 233 ? 106.833 110.774 116.450 1.00 68.87  ? 307 LEU A O   1 
ATOM 1367 C CB  . LEU A 1 233 ? 106.634 110.514 113.467 1.00 59.91  ? 307 LEU A CB  1 
ATOM 1368 C CG  . LEU A 1 233 ? 107.049 111.883 112.912 1.00 65.45  ? 307 LEU A CG  1 
ATOM 1369 C CD1 . LEU A 1 233 ? 106.383 112.128 111.574 1.00 64.48  ? 307 LEU A CD1 1 
ATOM 1370 C CD2 . LEU A 1 233 ? 106.689 113.012 113.866 1.00 63.53  ? 307 LEU A CD2 1 
ATOM 1371 N N   . ILE A 1 234 ? 109.014 110.961 115.908 1.00 57.79  ? 308 ILE A N   1 
ATOM 1372 C CA  . ILE A 1 234 ? 109.412 111.528 117.187 1.00 65.47  ? 308 ILE A CA  1 
ATOM 1373 C C   . ILE A 1 234 ? 109.477 113.046 117.128 1.00 69.08  ? 308 ILE A C   1 
ATOM 1374 O O   . ILE A 1 234 ? 108.974 113.733 118.022 1.00 76.56  ? 308 ILE A O   1 
ATOM 1375 C CB  . ILE A 1 234 ? 110.756 110.914 117.635 1.00 65.64  ? 308 ILE A CB  1 
ATOM 1376 C CG1 . ILE A 1 234 ? 111.791 110.992 116.512 1.00 64.45  ? 308 ILE A CG1 1 
ATOM 1377 C CG2 . ILE A 1 234 ? 110.559 109.472 118.057 1.00 65.58  ? 308 ILE A CG2 1 
ATOM 1378 C CD1 . ILE A 1 234 ? 113.125 110.376 116.866 1.00 65.38  ? 308 ILE A CD1 1 
ATOM 1379 N N   . THR A 1 235 ? 110.082 113.598 116.081 1.00 56.68  ? 309 THR A N   1 
ATOM 1380 C CA  . THR A 1 235 ? 110.238 115.041 116.000 1.00 64.16  ? 309 THR A CA  1 
ATOM 1381 C C   . THR A 1 235 ? 110.424 115.449 114.549 1.00 66.96  ? 309 THR A C   1 
ATOM 1382 O O   . THR A 1 235 ? 110.874 114.662 113.712 1.00 73.42  ? 309 THR A O   1 
ATOM 1383 C CB  . THR A 1 235 ? 111.418 115.526 116.850 1.00 69.42  ? 309 THR A CB  1 
ATOM 1384 O OG1 . THR A 1 235 ? 111.399 116.956 116.928 1.00 73.35  ? 309 THR A OG1 1 
ATOM 1385 C CG2 . THR A 1 235 ? 112.740 115.071 116.250 1.00 68.33  ? 309 THR A CG2 1 
ATOM 1386 N N   . THR A 1 236 ? 110.051 116.691 114.265 1.00 66.53  ? 310 THR A N   1 
ATOM 1387 C CA  . THR A 1 236 ? 110.337 117.342 112.995 1.00 68.16  ? 310 THR A CA  1 
ATOM 1388 C C   . THR A 1 236 ? 111.321 118.468 113.267 1.00 69.89  ? 310 THR A C   1 
ATOM 1389 O O   . THR A 1 236 ? 110.975 119.450 113.931 1.00 66.51  ? 310 THR A O   1 
ATOM 1390 C CB  . THR A 1 236 ? 109.063 117.881 112.346 1.00 70.00  ? 310 THR A CB  1 
ATOM 1391 O OG1 . THR A 1 236 ? 108.230 116.788 111.941 1.00 73.27  ? 310 THR A OG1 1 
ATOM 1392 C CG2 . THR A 1 236 ? 109.404 118.732 111.131 1.00 70.05  ? 310 THR A CG2 1 
ATOM 1393 N N   . VAL A 1 237 ? 112.537 118.326 112.759 1.00 74.82  ? 311 VAL A N   1 
ATOM 1394 C CA  . VAL A 1 237 ? 113.608 119.268 113.054 1.00 73.54  ? 311 VAL A CA  1 
ATOM 1395 C C   . VAL A 1 237 ? 113.580 120.396 112.032 1.00 72.67  ? 311 VAL A C   1 
ATOM 1396 O O   . VAL A 1 237 ? 113.535 120.159 110.819 1.00 74.48  ? 311 VAL A O   1 
ATOM 1397 C CB  . VAL A 1 237 ? 114.975 118.560 113.089 1.00 74.91  ? 311 VAL A CB  1 
ATOM 1398 C CG1 . VAL A 1 237 ? 115.326 117.952 111.742 1.00 71.70  ? 311 VAL A CG1 1 
ATOM 1399 C CG2 . VAL A 1 237 ? 116.060 119.528 113.541 1.00 72.79  ? 311 VAL A CG2 1 
ATOM 1400 N N   . GLN A 1 238 ? 113.563 121.629 112.529 1.00 69.76  ? 312 GLN A N   1 
ATOM 1401 C CA  . GLN A 1 238 ? 113.593 122.821 111.696 1.00 69.87  ? 312 GLN A CA  1 
ATOM 1402 C C   . GLN A 1 238 ? 114.863 123.594 112.004 1.00 70.44  ? 312 GLN A C   1 
ATOM 1403 O O   . GLN A 1 238 ? 115.168 123.859 113.171 1.00 73.13  ? 312 GLN A O   1 
ATOM 1404 C CB  . GLN A 1 238 ? 112.359 123.694 111.931 1.00 72.49  ? 312 GLN A CB  1 
ATOM 1405 C CG  . GLN A 1 238 ? 111.056 123.021 111.549 1.00 73.88  ? 312 GLN A CG  1 
ATOM 1406 C CD  . GLN A 1 238 ? 109.850 123.892 111.825 1.00 77.48  ? 312 GLN A CD  1 
ATOM 1407 O OE1 . GLN A 1 238 ? 109.959 124.940 112.461 1.00 77.19  ? 312 GLN A OE1 1 
ATOM 1408 N NE2 . GLN A 1 238 ? 108.689 123.463 111.344 1.00 74.74  ? 312 GLN A NE2 1 
ATOM 1409 N N   . GLY A 1 239 ? 115.587 123.951 110.968 1.00 60.22  ? 313 GLY A N   1 
ATOM 1410 C CA  . GLY A 1 239 ? 116.892 124.550 111.101 1.00 60.76  ? 313 GLY A CA  1 
ATOM 1411 C C   . GLY A 1 239 ? 117.763 124.129 109.933 1.00 61.47  ? 313 GLY A C   1 
ATOM 1412 O O   . GLY A 1 239 ? 117.268 123.905 108.831 1.00 65.37  ? 313 GLY A O   1 
ATOM 1413 N N   . ASP A 1 240 ? 119.064 124.028 110.196 1.00 53.88  ? 314 ASP A N   1 
ATOM 1414 C CA  . ASP A 1 240 ? 119.976 123.653 109.125 1.00 57.04  ? 314 ASP A CA  1 
ATOM 1415 C C   . ASP A 1 240 ? 119.888 122.167 108.793 1.00 56.06  ? 314 ASP A C   1 
ATOM 1416 O O   . ASP A 1 240 ? 119.847 121.804 107.614 1.00 65.34  ? 314 ASP A O   1 
ATOM 1417 C CB  . ASP A 1 240 ? 121.403 124.045 109.489 1.00 60.09  ? 314 ASP A CB  1 
ATOM 1418 C CG  . ASP A 1 240 ? 121.591 125.546 109.559 1.00 64.62  ? 314 ASP A CG  1 
ATOM 1419 O OD1 . ASP A 1 240 ? 120.616 126.279 109.296 1.00 65.27  ? 314 ASP A OD1 1 
ATOM 1420 O OD2 . ASP A 1 240 ? 122.713 125.994 109.879 1.00 64.07  ? 314 ASP A OD2 1 
ATOM 1421 N N   . GLY A 1 241 ? 119.842 121.294 109.795 1.00 40.30  ? 315 GLY A N   1 
ATOM 1422 C CA  . GLY A 1 241 ? 119.749 119.873 109.509 1.00 42.93  ? 315 GLY A CA  1 
ATOM 1423 C C   . GLY A 1 241 ? 119.978 119.020 110.742 1.00 39.56  ? 315 GLY A C   1 
ATOM 1424 O O   . GLY A 1 241 ? 119.802 119.475 111.872 1.00 38.30  ? 315 GLY A O   1 
ATOM 1425 N N   . VAL A 1 242 ? 120.373 117.767 110.495 1.00 34.85  ? 316 VAL A N   1 
ATOM 1426 C CA  . VAL A 1 242 ? 120.553 116.759 111.533 1.00 30.79  ? 316 VAL A CA  1 
ATOM 1427 C C   . VAL A 1 242 ? 121.813 115.951 111.228 1.00 40.96  ? 316 VAL A C   1 
ATOM 1428 O O   . VAL A 1 242 ? 122.161 115.726 110.066 1.00 44.80  ? 316 VAL A O   1 
ATOM 1429 C CB  . VAL A 1 242 ? 119.305 115.851 111.644 1.00 29.50  ? 316 VAL A CB  1 
ATOM 1430 C CG1 . VAL A 1 242 ? 119.034 115.145 110.328 1.00 36.67  ? 316 VAL A CG1 1 
ATOM 1431 C CG2 . VAL A 1 242 ? 119.451 114.853 112.781 1.00 43.18  ? 316 VAL A CG2 1 
ATOM 1432 N N   . ILE A 1 243 ? 122.502 115.516 112.288 1.00 37.99  ? 317 ILE A N   1 
ATOM 1433 C CA  . ILE A 1 243 ? 123.835 114.923 112.187 1.00 27.92  ? 317 ILE A CA  1 
ATOM 1434 C C   . ILE A 1 243 ? 123.827 113.509 112.765 1.00 32.30  ? 317 ILE A C   1 
ATOM 1435 O O   . ILE A 1 243 ? 124.701 113.158 113.565 1.00 51.36  ? 317 ILE A O   1 
ATOM 1436 C CB  . ILE A 1 243 ? 124.906 115.788 112.880 1.00 33.74  ? 317 ILE A CB  1 
ATOM 1437 C CG1 . ILE A 1 243 ? 124.912 117.197 112.324 1.00 40.43  ? 317 ILE A CG1 1 
ATOM 1438 C CG2 . ILE A 1 243 ? 126.308 115.298 112.548 1.00 41.15  ? 317 ILE A CG2 1 
ATOM 1439 C CD1 . ILE A 1 243 ? 125.794 118.122 113.124 1.00 42.84  ? 317 ILE A CD1 1 
ATOM 1440 N N   . VAL A 1 244 ? 122.787 112.729 112.470 1.00 21.48  ? 318 VAL A N   1 
ATOM 1441 C CA  . VAL A 1 244 ? 122.714 111.344 112.936 1.00 23.39  ? 318 VAL A CA  1 
ATOM 1442 C C   . VAL A 1 244 ? 124.067 110.666 112.758 1.00 31.24  ? 318 VAL A C   1 
ATOM 1443 O O   . VAL A 1 244 ? 124.620 110.641 111.653 1.00 43.93  ? 318 VAL A O   1 
ATOM 1444 C CB  . VAL A 1 244 ? 121.616 110.563 112.197 1.00 28.31  ? 318 VAL A CB  1 
ATOM 1445 C CG1 . VAL A 1 244 ? 121.755 109.081 112.476 1.00 34.24  ? 318 VAL A CG1 1 
ATOM 1446 C CG2 . VAL A 1 244 ? 120.244 111.060 112.612 1.00 38.91  ? 318 VAL A CG2 1 
ATOM 1447 N N   . SER A 1 245 ? 124.608 110.111 113.842 1.00 37.83  ? 319 SER A N   1 
ATOM 1448 C CA  . SER A 1 245 ? 126.018 109.752 113.881 1.00 27.70  ? 319 SER A CA  1 
ATOM 1449 C C   . SER A 1 245 ? 126.245 108.556 114.791 1.00 39.82  ? 319 SER A C   1 
ATOM 1450 O O   . SER A 1 245 ? 125.416 108.223 115.641 1.00 50.35  ? 319 SER A O   1 
ATOM 1451 C CB  . SER A 1 245 ? 126.873 110.926 114.362 1.00 36.86  ? 319 SER A CB  1 
ATOM 1452 O OG  . SER A 1 245 ? 126.493 111.328 115.664 1.00 34.47  ? 319 SER A OG  1 
ATOM 1453 N N   . THR A 1 246 ? 127.394 107.915 114.595 1.00 48.03  ? 320 THR A N   1 
ATOM 1454 C CA  . THR A 1 246 ? 127.884 106.856 115.459 1.00 41.48  ? 320 THR A CA  1 
ATOM 1455 C C   . THR A 1 246 ? 128.623 107.450 116.654 1.00 50.13  ? 320 THR A C   1 
ATOM 1456 O O   . THR A 1 246 ? 128.956 108.638 116.661 1.00 57.38  ? 320 THR A O   1 
ATOM 1457 C CB  . THR A 1 246 ? 128.820 105.936 114.684 1.00 40.19  ? 320 THR A CB  1 
ATOM 1458 O OG1 . THR A 1 246 ? 129.947 106.687 114.219 1.00 48.91  ? 320 THR A OG1 1 
ATOM 1459 C CG2 . THR A 1 246 ? 128.111 105.325 113.500 1.00 50.64  ? 320 THR A CG2 1 
ATOM 1460 N N   . PRO A 1 247 ? 128.883 106.646 117.690 1.00 45.37  ? 321 PRO A N   1 
ATOM 1461 C CA  . PRO A 1 247 ? 129.717 107.138 118.795 1.00 38.77  ? 321 PRO A CA  1 
ATOM 1462 C C   . PRO A 1 247 ? 131.099 107.582 118.355 1.00 50.67  ? 321 PRO A C   1 
ATOM 1463 O O   . PRO A 1 247 ? 131.682 108.474 118.983 1.00 51.00  ? 321 PRO A O   1 
ATOM 1464 C CB  . PRO A 1 247 ? 129.786 105.932 119.736 1.00 44.57  ? 321 PRO A CB  1 
ATOM 1465 C CG  . PRO A 1 247 ? 128.525 105.211 119.488 1.00 51.83  ? 321 PRO A CG  1 
ATOM 1466 C CD  . PRO A 1 247 ? 128.246 105.360 118.022 1.00 51.67  ? 321 PRO A CD  1 
ATOM 1467 N N   . THR A 1 248 ? 131.648 106.980 117.298 1.00 57.78  ? 322 THR A N   1 
ATOM 1468 C CA  . THR A 1 248 ? 132.941 107.419 116.785 1.00 50.67  ? 322 THR A CA  1 
ATOM 1469 C C   . THR A 1 248 ? 132.865 108.829 116.219 1.00 52.82  ? 322 THR A C   1 
ATOM 1470 O O   . THR A 1 248 ? 133.840 109.585 116.302 1.00 57.12  ? 322 THR A O   1 
ATOM 1471 C CB  . THR A 1 248 ? 133.439 106.451 115.718 1.00 46.33  ? 322 THR A CB  1 
ATOM 1472 O OG1 . THR A 1 248 ? 132.697 106.650 114.509 1.00 56.89  ? 322 THR A OG1 1 
ATOM 1473 C CG2 . THR A 1 248 ? 133.245 105.029 116.184 1.00 52.37  ? 322 THR A CG2 1 
ATOM 1474 N N   . GLY A 1 249 ? 131.726 109.199 115.643 1.00 46.39  ? 323 GLY A N   1 
ATOM 1475 C CA  . GLY A 1 249 ? 131.511 110.537 115.142 1.00 43.53  ? 323 GLY A CA  1 
ATOM 1476 C C   . GLY A 1 249 ? 131.097 111.550 116.178 1.00 51.50  ? 323 GLY A C   1 
ATOM 1477 O O   . GLY A 1 249 ? 130.869 112.712 115.836 1.00 55.42  ? 323 GLY A O   1 
ATOM 1478 N N   . SER A 1 250 ? 130.983 111.139 117.444 1.00 57.67  ? 324 SER A N   1 
ATOM 1479 C CA  . SER A 1 250 ? 130.623 112.070 118.506 1.00 57.60  ? 324 SER A CA  1 
ATOM 1480 C C   . SER A 1 250 ? 131.664 113.163 118.688 1.00 61.20  ? 324 SER A C   1 
ATOM 1481 O O   . SER A 1 250 ? 131.322 114.261 119.140 1.00 64.18  ? 324 SER A O   1 
ATOM 1482 C CB  . SER A 1 250 ? 130.426 111.319 119.821 1.00 59.93  ? 324 SER A CB  1 
ATOM 1483 O OG  . SER A 1 250 ? 131.607 110.629 120.193 1.00 62.59  ? 324 SER A OG  1 
ATOM 1484 N N   . THR A 1 251 ? 132.924 112.886 118.362 1.00 58.26  ? 325 THR A N   1 
ATOM 1485 C CA  . THR A 1 251 ? 133.980 113.887 118.367 1.00 60.19  ? 325 THR A CA  1 
ATOM 1486 C C   . THR A 1 251 ? 134.172 114.532 117.002 1.00 61.28  ? 325 THR A C   1 
ATOM 1487 O O   . THR A 1 251 ? 135.043 115.393 116.851 1.00 64.32  ? 325 THR A O   1 
ATOM 1488 C CB  . THR A 1 251 ? 135.297 113.261 118.832 1.00 65.95  ? 325 THR A CB  1 
ATOM 1489 O OG1 . THR A 1 251 ? 135.696 112.244 117.906 1.00 63.15  ? 325 THR A OG1 1 
ATOM 1490 C CG2 . THR A 1 251 ? 135.126 112.640 120.209 1.00 61.90  ? 325 THR A CG2 1 
ATOM 1491 N N   . ALA A 1 252 ? 133.378 114.138 116.017 1.00 56.67  ? 326 ALA A N   1 
ATOM 1492 C CA  . ALA A 1 252 ? 133.440 114.672 114.666 1.00 56.89  ? 326 ALA A CA  1 
ATOM 1493 C C   . ALA A 1 252 ? 132.503 115.875 114.566 1.00 55.56  ? 326 ALA A C   1 
ATOM 1494 O O   . ALA A 1 252 ? 132.111 116.455 115.582 1.00 57.83  ? 326 ALA A O   1 
ATOM 1495 C CB  . ALA A 1 252 ? 133.110 113.572 113.653 1.00 53.60  ? 326 ALA A CB  1 
ATOM 1496 N N   . TYR A 1 253 ? 132.170 116.283 113.338 1.00 45.79  ? 327 TYR A N   1 
ATOM 1497 C CA  . TYR A 1 253 ? 131.294 117.425 113.091 1.00 44.32  ? 327 TYR A CA  1 
ATOM 1498 C C   . TYR A 1 253 ? 130.049 117.438 113.974 1.00 49.01  ? 327 TYR A C   1 
ATOM 1499 O O   . TYR A 1 253 ? 129.498 118.514 114.231 1.00 57.91  ? 327 TYR A O   1 
ATOM 1500 C CB  . TYR A 1 253 ? 130.894 117.434 111.613 1.00 50.00  ? 327 TYR A CB  1 
ATOM 1501 C CG  . TYR A 1 253 ? 129.873 118.478 111.233 1.00 50.98  ? 327 TYR A CG  1 
ATOM 1502 C CD1 . TYR A 1 253 ? 130.102 119.823 111.480 1.00 54.25  ? 327 TYR A CD1 1 
ATOM 1503 C CD2 . TYR A 1 253 ? 128.693 118.122 110.601 1.00 46.10  ? 327 TYR A CD2 1 
ATOM 1504 C CE1 . TYR A 1 253 ? 129.175 120.780 111.126 1.00 50.07  ? 327 TYR A CE1 1 
ATOM 1505 C CE2 . TYR A 1 253 ? 127.763 119.070 110.243 1.00 46.29  ? 327 TYR A CE2 1 
ATOM 1506 C CZ  . TYR A 1 253 ? 128.009 120.397 110.505 1.00 49.21  ? 327 TYR A CZ  1 
ATOM 1507 O OH  . TYR A 1 253 ? 127.081 121.346 110.149 1.00 56.35  ? 327 TYR A OH  1 
ATOM 1508 N N   . ALA A 1 254 ? 129.595 116.276 114.450 1.00 47.36  ? 328 ALA A N   1 
ATOM 1509 C CA  . ALA A 1 254 ? 128.485 116.250 115.396 1.00 43.81  ? 328 ALA A CA  1 
ATOM 1510 C C   . ALA A 1 254 ? 128.823 116.992 116.681 1.00 37.44  ? 328 ALA A C   1 
ATOM 1511 O O   . ALA A 1 254 ? 127.937 117.585 117.305 1.00 42.00  ? 328 ALA A O   1 
ATOM 1512 C CB  . ALA A 1 254 ? 128.091 114.808 115.710 1.00 41.13  ? 328 ALA A CB  1 
ATOM 1513 N N   . ALA A 1 255 ? 130.093 116.970 117.093 1.00 43.79  ? 329 ALA A N   1 
ATOM 1514 C CA  . ALA A 1 255 ? 130.492 117.673 118.307 1.00 41.30  ? 329 ALA A CA  1 
ATOM 1515 C C   . ALA A 1 255 ? 130.335 119.178 118.153 1.00 45.66  ? 329 ALA A C   1 
ATOM 1516 O O   . ALA A 1 255 ? 129.976 119.873 119.110 1.00 56.16  ? 329 ALA A O   1 
ATOM 1517 C CB  . ALA A 1 255 ? 131.934 117.325 118.672 1.00 45.45  ? 329 ALA A CB  1 
ATOM 1518 N N   . ALA A 1 256 ? 130.608 119.702 116.957 1.00 38.55  ? 330 ALA A N   1 
ATOM 1519 C CA  . ALA A 1 256 ? 130.499 121.137 116.732 1.00 40.60  ? 330 ALA A CA  1 
ATOM 1520 C C   . ALA A 1 256 ? 129.069 121.637 116.870 1.00 49.76  ? 330 ALA A C   1 
ATOM 1521 O O   . ALA A 1 256 ? 128.857 122.846 117.002 1.00 52.66  ? 330 ALA A O   1 
ATOM 1522 C CB  . ALA A 1 256 ? 131.044 121.494 115.350 1.00 37.50  ? 330 ALA A CB  1 
ATOM 1523 N N   . ALA A 1 257 ? 128.089 120.738 116.854 1.00 54.21  ? 331 ALA A N   1 
ATOM 1524 C CA  . ALA A 1 257 ? 126.686 121.102 116.963 1.00 43.85  ? 331 ALA A CA  1 
ATOM 1525 C C   . ALA A 1 257 ? 126.157 120.986 118.386 1.00 44.41  ? 331 ALA A C   1 
ATOM 1526 O O   . ALA A 1 257 ? 124.942 121.065 118.592 1.00 53.17  ? 331 ALA A O   1 
ATOM 1527 C CB  . ALA A 1 257 ? 125.849 120.241 116.021 1.00 43.22  ? 331 ALA A CB  1 
ATOM 1528 N N   . GLY A 1 258 ? 127.034 120.799 119.367 1.00 46.36  ? 332 GLY A N   1 
ATOM 1529 C CA  . GLY A 1 258 ? 126.625 120.703 120.751 1.00 50.97  ? 332 GLY A CA  1 
ATOM 1530 C C   . GLY A 1 258 ? 126.407 119.301 121.269 1.00 48.13  ? 332 GLY A C   1 
ATOM 1531 O O   . GLY A 1 258 ? 125.882 119.145 122.378 1.00 48.87  ? 332 GLY A O   1 
ATOM 1532 N N   . ALA A 1 259 ? 126.793 118.279 120.513 1.00 50.09  ? 333 ALA A N   1 
ATOM 1533 C CA  . ALA A 1 259 ? 126.581 116.907 120.944 1.00 49.13  ? 333 ALA A CA  1 
ATOM 1534 C C   . ALA A 1 259 ? 127.570 116.519 122.035 1.00 49.06  ? 333 ALA A C   1 
ATOM 1535 O O   . ALA A 1 259 ? 128.722 116.959 122.049 1.00 56.12  ? 333 ALA A O   1 
ATOM 1536 C CB  . ALA A 1 259 ? 126.710 115.948 119.762 1.00 51.15  ? 333 ALA A CB  1 
ATOM 1537 N N   . SER A 1 260 ? 127.104 115.684 122.958 1.00 49.85  ? 334 SER A N   1 
ATOM 1538 C CA  . SER A 1 260 ? 127.980 115.133 123.977 1.00 49.25  ? 334 SER A CA  1 
ATOM 1539 C C   . SER A 1 260 ? 128.927 114.111 123.357 1.00 53.21  ? 334 SER A C   1 
ATOM 1540 O O   . SER A 1 260 ? 128.665 113.543 122.294 1.00 59.69  ? 334 SER A O   1 
ATOM 1541 C CB  . SER A 1 260 ? 127.165 114.491 125.098 1.00 52.28  ? 334 SER A CB  1 
ATOM 1542 O OG  . SER A 1 260 ? 126.343 113.451 124.598 1.00 62.31  ? 334 SER A OG  1 
ATOM 1543 N N   . MET A 1 261 ? 130.041 113.876 124.040 1.00 48.69  ? 335 MET A N   1 
ATOM 1544 C CA  . MET A 1 261 ? 131.119 113.045 123.520 1.00 45.86  ? 335 MET A CA  1 
ATOM 1545 C C   . MET A 1 261 ? 130.962 111.629 124.060 1.00 42.82  ? 335 MET A C   1 
ATOM 1546 O O   . MET A 1 261 ? 131.088 111.400 125.267 1.00 58.84  ? 335 MET A O   1 
ATOM 1547 C CB  . MET A 1 261 ? 132.472 113.645 123.889 1.00 53.01  ? 335 MET A CB  1 
ATOM 1548 C CG  . MET A 1 261 ? 132.600 115.101 123.469 1.00 53.40  ? 335 MET A CG  1 
ATOM 1549 S SD  . MET A 1 261 ? 134.260 115.763 123.648 1.00 70.57  ? 335 MET A SD  1 
ATOM 1550 C CE  . MET A 1 261 ? 134.613 115.301 125.338 1.00 57.20  ? 335 MET A CE  1 
ATOM 1551 N N   . ILE A 1 262 ? 130.692 110.685 123.164 1.00 33.80  ? 336 ILE A N   1 
ATOM 1552 C CA  . ILE A 1 262 ? 130.391 109.306 123.527 1.00 41.04  ? 336 ILE A CA  1 
ATOM 1553 C C   . ILE A 1 262 ? 131.621 108.447 123.275 1.00 47.23  ? 336 ILE A C   1 
ATOM 1554 O O   . ILE A 1 262 ? 132.240 108.531 122.208 1.00 58.06  ? 336 ILE A O   1 
ATOM 1555 C CB  . ILE A 1 262 ? 129.184 108.776 122.736 1.00 51.78  ? 336 ILE A CB  1 
ATOM 1556 C CG1 . ILE A 1 262 ? 127.947 109.630 123.012 1.00 53.82  ? 336 ILE A CG1 1 
ATOM 1557 C CG2 . ILE A 1 262 ? 128.917 107.322 123.081 1.00 54.74  ? 336 ILE A CG2 1 
ATOM 1558 C CD1 . ILE A 1 262 ? 126.659 109.020 122.512 1.00 53.37  ? 336 ILE A CD1 1 
ATOM 1559 N N   . HIS A 1 263 ? 131.976 107.624 124.255 1.00 47.22  ? 337 HIS A N   1 
ATOM 1560 C CA  . HIS A 1 263 ? 133.068 106.679 124.080 1.00 47.40  ? 337 HIS A CA  1 
ATOM 1561 C C   . HIS A 1 263 ? 132.675 105.611 123.061 1.00 52.03  ? 337 HIS A C   1 
ATOM 1562 O O   . HIS A 1 263 ? 131.525 105.165 123.041 1.00 59.10  ? 337 HIS A O   1 
ATOM 1563 C CB  . HIS A 1 263 ? 133.423 106.033 125.417 1.00 50.10  ? 337 HIS A CB  1 
ATOM 1564 C CG  . HIS A 1 263 ? 134.649 105.177 125.373 1.00 54.20  ? 337 HIS A CG  1 
ATOM 1565 N ND1 . HIS A 1 263 ? 134.620 103.857 124.981 1.00 56.13  ? 337 HIS A ND1 1 
ATOM 1566 C CD2 . HIS A 1 263 ? 135.939 105.452 125.674 1.00 57.69  ? 337 HIS A CD2 1 
ATOM 1567 C CE1 . HIS A 1 263 ? 135.840 103.355 125.042 1.00 53.05  ? 337 HIS A CE1 1 
ATOM 1568 N NE2 . HIS A 1 263 ? 136.660 104.303 125.457 1.00 55.76  ? 337 HIS A NE2 1 
ATOM 1569 N N   . PRO A 1 264 ? 133.605 105.178 122.204 1.00 48.02  ? 338 PRO A N   1 
ATOM 1570 C CA  . PRO A 1 264 ? 133.243 104.252 121.120 1.00 47.74  ? 338 PRO A CA  1 
ATOM 1571 C C   . PRO A 1 264 ? 132.860 102.851 121.573 1.00 49.30  ? 338 PRO A C   1 
ATOM 1572 O O   . PRO A 1 264 ? 132.538 102.019 120.718 1.00 52.69  ? 338 PRO A O   1 
ATOM 1573 C CB  . PRO A 1 264 ? 134.509 104.224 120.252 1.00 51.19  ? 338 PRO A CB  1 
ATOM 1574 C CG  . PRO A 1 264 ? 135.602 104.637 121.155 1.00 51.37  ? 338 PRO A CG  1 
ATOM 1575 C CD  . PRO A 1 264 ? 134.999 105.636 122.088 1.00 50.05  ? 338 PRO A CD  1 
ATOM 1576 N N   . ASN A 1 265 ? 132.875 102.549 122.867 1.00 59.11  ? 339 ASN A N   1 
ATOM 1577 C CA  . ASN A 1 265 ? 132.386 101.267 123.356 1.00 59.58  ? 339 ASN A CA  1 
ATOM 1578 C C   . ASN A 1 265 ? 130.945 101.330 123.842 1.00 55.99  ? 339 ASN A C   1 
ATOM 1579 O O   . ASN A 1 265 ? 130.437 100.332 124.362 1.00 59.86  ? 339 ASN A O   1 
ATOM 1580 C CB  . ASN A 1 265 ? 133.286 100.744 124.479 1.00 58.43  ? 339 ASN A CB  1 
ATOM 1581 C CG  . ASN A 1 265 ? 134.570 100.135 123.959 1.00 63.99  ? 339 ASN A CG  1 
ATOM 1582 O OD1 . ASN A 1 265 ? 134.627 99.653  122.829 1.00 63.29  ? 339 ASN A OD1 1 
ATOM 1583 N ND2 . ASN A 1 265 ? 135.610 100.151 124.783 1.00 65.69  ? 339 ASN A ND2 1 
ATOM 1584 N N   . VAL A 1 266 ? 130.280 102.469 123.689 1.00 53.31  ? 340 VAL A N   1 
ATOM 1585 C CA  . VAL A 1 266 ? 128.877 102.619 124.061 1.00 49.35  ? 340 VAL A CA  1 
ATOM 1586 C C   . VAL A 1 266 ? 128.032 102.356 122.818 1.00 60.88  ? 340 VAL A C   1 
ATOM 1587 O O   . VAL A 1 266 ? 128.116 103.132 121.855 1.00 69.98  ? 340 VAL A O   1 
ATOM 1588 C CB  . VAL A 1 266 ? 128.595 104.015 124.623 1.00 47.84  ? 340 VAL A CB  1 
ATOM 1589 C CG1 . VAL A 1 266 ? 127.118 104.171 124.931 1.00 56.86  ? 340 VAL A CG1 1 
ATOM 1590 C CG2 . VAL A 1 266 ? 129.435 104.266 125.860 1.00 56.00  ? 340 VAL A CG2 1 
ATOM 1591 N N   . PRO A 1 267 ? 127.224 101.301 122.793 1.00 51.69  ? 341 PRO A N   1 
ATOM 1592 C CA  . PRO A 1 267 ? 126.372 101.033 121.626 1.00 47.04  ? 341 PRO A CA  1 
ATOM 1593 C C   . PRO A 1 267 ? 125.151 101.938 121.619 1.00 51.18  ? 341 PRO A C   1 
ATOM 1594 O O   . PRO A 1 267 ? 124.223 101.764 122.416 1.00 54.80  ? 341 PRO A O   1 
ATOM 1595 C CB  . PRO A 1 267 ? 125.995 99.557  121.808 1.00 47.69  ? 341 PRO A CB  1 
ATOM 1596 C CG  . PRO A 1 267 ? 126.061 99.336  123.271 1.00 45.91  ? 341 PRO A CG  1 
ATOM 1597 C CD  . PRO A 1 267 ? 127.139 100.234 123.803 1.00 47.56  ? 341 PRO A CD  1 
ATOM 1598 N N   . ALA A 1 268 ? 125.145 102.909 120.709 1.00 45.00  ? 342 ALA A N   1 
ATOM 1599 C CA  . ALA A 1 268 ? 124.057 103.874 120.627 1.00 44.46  ? 342 ALA A CA  1 
ATOM 1600 C C   . ALA A 1 268 ? 124.154 104.623 119.307 1.00 39.67  ? 342 ALA A C   1 
ATOM 1601 O O   . ALA A 1 268 ? 125.186 104.596 118.632 1.00 41.17  ? 342 ALA A O   1 
ATOM 1602 C CB  . ALA A 1 268 ? 124.091 104.851 121.803 1.00 43.33  ? 342 ALA A CB  1 
ATOM 1603 N N   . ILE A 1 269 ? 123.058 105.288 118.949 1.00 38.92  ? 343 ILE A N   1 
ATOM 1604 C CA  . ILE A 1 269 ? 122.981 106.137 117.766 1.00 37.13  ? 343 ILE A CA  1 
ATOM 1605 C C   . ILE A 1 269 ? 122.554 107.524 118.217 1.00 39.90  ? 343 ILE A C   1 
ATOM 1606 O O   . ILE A 1 269 ? 121.556 107.667 118.932 1.00 49.37  ? 343 ILE A O   1 
ATOM 1607 C CB  . ILE A 1 269 ? 121.992 105.583 116.724 1.00 33.89  ? 343 ILE A CB  1 
ATOM 1608 C CG1 . ILE A 1 269 ? 122.417 104.197 116.249 1.00 39.82  ? 343 ILE A CG1 1 
ATOM 1609 C CG2 . ILE A 1 269 ? 121.886 106.523 115.542 1.00 38.02  ? 343 ILE A CG2 1 
ATOM 1610 C CD1 . ILE A 1 269 ? 121.494 103.619 115.205 1.00 43.78  ? 343 ILE A CD1 1 
ATOM 1611 N N   . MET A 1 270 ? 123.294 108.539 117.794 1.00 31.75  ? 344 MET A N   1 
ATOM 1612 C CA  . MET A 1 270 ? 123.033 109.910 118.197 1.00 32.28  ? 344 MET A CA  1 
ATOM 1613 C C   . MET A 1 270 ? 122.213 110.638 117.141 1.00 43.47  ? 344 MET A C   1 
ATOM 1614 O O   . MET A 1 270 ? 122.318 110.359 115.945 1.00 51.33  ? 344 MET A O   1 
ATOM 1615 C CB  . MET A 1 270 ? 124.341 110.663 118.433 1.00 32.24  ? 344 MET A CB  1 
ATOM 1616 C CG  . MET A 1 270 ? 125.347 109.901 119.259 1.00 42.28  ? 344 MET A CG  1 
ATOM 1617 S SD  . MET A 1 270 ? 126.894 110.802 119.418 1.00 66.94  ? 344 MET A SD  1 
ATOM 1618 C CE  . MET A 1 270 ? 126.325 112.291 120.229 1.00 48.71  ? 344 MET A CE  1 
ATOM 1619 N N   . ILE A 1 271 ? 121.383 111.571 117.601 1.00 31.70  ? 345 ILE A N   1 
ATOM 1620 C CA  . ILE A 1 271 ? 120.656 112.489 116.732 1.00 22.89  ? 345 ILE A CA  1 
ATOM 1621 C C   . ILE A 1 271 ? 120.936 113.901 117.219 1.00 28.52  ? 345 ILE A C   1 
ATOM 1622 O O   . ILE A 1 271 ? 120.571 114.254 118.346 1.00 35.42  ? 345 ILE A O   1 
ATOM 1623 C CB  . ILE A 1 271 ? 119.146 112.206 116.718 1.00 18.93  ? 345 ILE A CB  1 
ATOM 1624 C CG1 . ILE A 1 271 ? 118.872 110.795 116.201 1.00 20.70  ? 345 ILE A CG1 1 
ATOM 1625 C CG2 . ILE A 1 271 ? 118.425 113.226 115.863 1.00 32.76  ? 345 ILE A CG2 1 
ATOM 1626 C CD1 . ILE A 1 271 ? 117.408 110.438 116.163 1.00 33.70  ? 345 ILE A CD1 1 
ATOM 1627 N N   . THR A 1 272 ? 121.581 114.707 116.377 1.00 36.01  ? 346 THR A N   1 
ATOM 1628 C CA  . THR A 1 272 ? 122.018 116.040 116.760 1.00 30.04  ? 346 THR A CA  1 
ATOM 1629 C C   . THR A 1 272 ? 121.628 117.039 115.678 1.00 41.61  ? 346 THR A C   1 
ATOM 1630 O O   . THR A 1 272 ? 121.938 116.824 114.494 1.00 49.21  ? 346 THR A O   1 
ATOM 1631 C CB  . THR A 1 272 ? 123.532 116.068 116.986 1.00 33.66  ? 346 THR A CB  1 
ATOM 1632 O OG1 . THR A 1 272 ? 123.888 115.076 117.956 1.00 43.60  ? 346 THR A OG1 1 
ATOM 1633 C CG2 . THR A 1 272 ? 123.969 117.430 117.488 1.00 34.13  ? 346 THR A CG2 1 
ATOM 1634 N N   . PRO A 1 273 ? 120.961 118.132 116.033 1.00 42.96  ? 347 PRO A N   1 
ATOM 1635 C CA  . PRO A 1 273 ? 120.577 119.137 115.039 1.00 43.66  ? 347 PRO A CA  1 
ATOM 1636 C C   . PRO A 1 273 ? 121.751 120.035 114.672 1.00 47.16  ? 347 PRO A C   1 
ATOM 1637 O O   . PRO A 1 273 ? 122.796 120.041 115.320 1.00 56.42  ? 347 PRO A O   1 
ATOM 1638 C CB  . PRO A 1 273 ? 119.496 119.938 115.759 1.00 37.80  ? 347 PRO A CB  1 
ATOM 1639 C CG  . PRO A 1 273 ? 119.892 119.844 117.189 1.00 40.40  ? 347 PRO A CG  1 
ATOM 1640 C CD  . PRO A 1 273 ? 120.456 118.466 117.374 1.00 38.99  ? 347 PRO A CD  1 
ATOM 1641 N N   . ILE A 1 274 ? 121.552 120.810 113.611 1.00 44.28  ? 348 ILE A N   1 
ATOM 1642 C CA  . ILE A 1 274 ? 122.479 121.864 113.219 1.00 45.31  ? 348 ILE A CA  1 
ATOM 1643 C C   . ILE A 1 274 ? 121.714 123.168 113.383 1.00 53.03  ? 348 ILE A C   1 
ATOM 1644 O O   . ILE A 1 274 ? 120.889 123.520 112.530 1.00 56.40  ? 348 ILE A O   1 
ATOM 1645 C CB  . ILE A 1 274 ? 122.984 121.705 111.783 1.00 48.46  ? 348 ILE A CB  1 
ATOM 1646 C CG1 . ILE A 1 274 ? 123.669 120.363 111.595 1.00 47.35  ? 348 ILE A CG1 1 
ATOM 1647 C CG2 . ILE A 1 274 ? 123.991 122.795 111.466 1.00 50.32  ? 348 ILE A CG2 1 
ATOM 1648 C CD1 . ILE A 1 274 ? 123.973 120.036 110.151 1.00 51.81  ? 348 ILE A CD1 1 
ATOM 1649 N N   . CYS A 1 275 ? 121.976 123.885 114.471 1.00 54.39  ? 349 CYS A N   1 
ATOM 1650 C CA  . CYS A 1 275 ? 121.313 125.151 114.754 1.00 51.97  ? 349 CYS A CA  1 
ATOM 1651 C C   . CYS A 1 275 ? 119.797 124.994 114.698 1.00 54.42  ? 349 CYS A C   1 
ATOM 1652 O O   . CYS A 1 275 ? 119.154 125.539 113.793 1.00 61.56  ? 349 CYS A O   1 
ATOM 1653 C CB  . CYS A 1 275 ? 121.770 126.227 113.768 1.00 56.71  ? 349 CYS A CB  1 
ATOM 1654 S SG  . CYS A 1 275 ? 123.540 126.569 113.804 1.00 58.95  ? 349 CYS A SG  1 
ATOM 1655 N N   . PRO A 1 276 ? 119.193 124.254 115.626 1.00 54.11  ? 350 PRO A N   1 
ATOM 1656 C CA  . PRO A 1 276 ? 117.740 124.075 115.585 1.00 52.45  ? 350 PRO A CA  1 
ATOM 1657 C C   . PRO A 1 276 ? 117.009 125.378 115.858 1.00 55.88  ? 350 PRO A C   1 
ATOM 1658 O O   . PRO A 1 276 ? 117.465 126.226 116.629 1.00 57.99  ? 350 PRO A O   1 
ATOM 1659 C CB  . PRO A 1 276 ? 117.480 123.053 116.696 1.00 57.92  ? 350 PRO A CB  1 
ATOM 1660 C CG  . PRO A 1 276 ? 118.595 123.264 117.648 1.00 58.36  ? 350 PRO A CG  1 
ATOM 1661 C CD  . PRO A 1 276 ? 119.790 123.618 116.812 1.00 59.13  ? 350 PRO A CD  1 
ATOM 1662 N N   . HIS A 1 277 ? 115.854 125.532 115.208 1.00 63.38  ? 351 HIS A N   1 
ATOM 1663 C CA  . HIS A 1 277 ? 115.044 126.723 115.435 1.00 64.56  ? 351 HIS A CA  1 
ATOM 1664 C C   . HIS A 1 277 ? 114.449 126.722 116.837 1.00 69.40  ? 351 HIS A C   1 
ATOM 1665 O O   . HIS A 1 277 ? 114.411 127.764 117.501 1.00 72.37  ? 351 HIS A O   1 
ATOM 1666 C CB  . HIS A 1 277 ? 113.943 126.821 114.382 1.00 65.85  ? 351 HIS A CB  1 
ATOM 1667 C CG  . HIS A 1 277 ? 113.136 128.078 114.470 1.00 74.20  ? 351 HIS A CG  1 
ATOM 1668 N ND1 . HIS A 1 277 ? 113.661 129.320 114.183 1.00 74.25  ? 351 HIS A ND1 1 
ATOM 1669 C CD2 . HIS A 1 277 ? 111.843 128.287 114.813 1.00 74.25  ? 351 HIS A CD2 1 
ATOM 1670 C CE1 . HIS A 1 277 ? 112.726 130.239 114.345 1.00 75.63  ? 351 HIS A CE1 1 
ATOM 1671 N NE2 . HIS A 1 277 ? 111.613 129.638 114.727 1.00 73.63  ? 351 HIS A NE2 1 
ATOM 1672 N N   . SER A 1 278 ? 113.980 125.567 117.302 1.00 65.16  ? 352 SER A N   1 
ATOM 1673 C CA  . SER A 1 278 ? 113.489 125.439 118.667 1.00 62.34  ? 352 SER A CA  1 
ATOM 1674 C C   . SER A 1 278 ? 114.666 125.388 119.629 1.00 60.12  ? 352 SER A C   1 
ATOM 1675 O O   . SER A 1 278 ? 115.609 124.616 119.430 1.00 64.97  ? 352 SER A O   1 
ATOM 1676 C CB  . SER A 1 278 ? 112.631 124.184 118.813 1.00 64.63  ? 352 SER A CB  1 
ATOM 1677 O OG  . SER A 1 278 ? 112.259 123.977 120.165 1.00 62.39  ? 352 SER A OG  1 
ATOM 1678 N N   . LEU A 1 279 ? 114.610 126.206 120.677 1.00 58.26  ? 353 LEU A N   1 
ATOM 1679 C CA  . LEU A 1 279 ? 115.731 126.305 121.600 1.00 61.88  ? 353 LEU A CA  1 
ATOM 1680 C C   . LEU A 1 279 ? 115.720 125.220 122.667 1.00 61.54  ? 353 LEU A C   1 
ATOM 1681 O O   . LEU A 1 279 ? 116.662 125.150 123.463 1.00 62.21  ? 353 LEU A O   1 
ATOM 1682 C CB  . LEU A 1 279 ? 115.755 127.684 122.265 1.00 63.29  ? 353 LEU A CB  1 
ATOM 1683 C CG  . LEU A 1 279 ? 116.419 128.813 121.468 1.00 66.84  ? 353 LEU A CG  1 
ATOM 1684 C CD1 . LEU A 1 279 ? 117.884 128.488 121.202 1.00 63.51  ? 353 LEU A CD1 1 
ATOM 1685 C CD2 . LEU A 1 279 ? 115.693 129.128 120.168 1.00 64.40  ? 353 LEU A CD2 1 
ATOM 1686 N N   . SER A 1 280 ? 114.689 124.382 122.705 1.00 60.59  ? 354 SER A N   1 
ATOM 1687 C CA  . SER A 1 280 ? 114.613 123.275 123.647 1.00 62.07  ? 354 SER A CA  1 
ATOM 1688 C C   . SER A 1 280 ? 114.965 121.934 123.020 1.00 62.12  ? 354 SER A C   1 
ATOM 1689 O O   . SER A 1 280 ? 114.809 120.901 123.679 1.00 61.92  ? 354 SER A O   1 
ATOM 1690 C CB  . SER A 1 280 ? 113.212 123.196 124.257 1.00 61.13  ? 354 SER A CB  1 
ATOM 1691 O OG  . SER A 1 280 ? 112.226 123.058 123.250 1.00 62.50  ? 354 SER A OG  1 
ATOM 1692 N N   . PHE A 1 281 ? 115.430 121.920 121.775 1.00 59.22  ? 355 PHE A N   1 
ATOM 1693 C CA  . PHE A 1 281 ? 115.718 120.667 121.092 1.00 57.42  ? 355 PHE A CA  1 
ATOM 1694 C C   . PHE A 1 281 ? 117.154 120.251 121.382 1.00 52.85  ? 355 PHE A C   1 
ATOM 1695 O O   . PHE A 1 281 ? 118.100 120.957 121.023 1.00 56.16  ? 355 PHE A O   1 
ATOM 1696 C CB  . PHE A 1 281 ? 115.481 120.819 119.589 1.00 53.82  ? 355 PHE A CB  1 
ATOM 1697 C CG  . PHE A 1 281 ? 115.626 119.541 118.814 1.00 59.25  ? 355 PHE A CG  1 
ATOM 1698 C CD1 . PHE A 1 281 ? 114.646 118.567 118.875 1.00 59.73  ? 355 PHE A CD1 1 
ATOM 1699 C CD2 . PHE A 1 281 ? 116.719 119.324 118.004 1.00 61.27  ? 355 PHE A CD2 1 
ATOM 1700 C CE1 . PHE A 1 281 ? 114.767 117.394 118.157 1.00 61.36  ? 355 PHE A CE1 1 
ATOM 1701 C CE2 . PHE A 1 281 ? 116.846 118.150 117.283 1.00 60.12  ? 355 PHE A CE2 1 
ATOM 1702 C CZ  . PHE A 1 281 ? 115.870 117.186 117.360 1.00 61.83  ? 355 PHE A CZ  1 
ATOM 1703 N N   . ARG A 1 282 ? 117.311 119.105 122.039 1.00 51.21  ? 356 ARG A N   1 
ATOM 1704 C CA  . ARG A 1 282 ? 118.593 118.649 122.543 1.00 50.71  ? 356 ARG A CA  1 
ATOM 1705 C C   . ARG A 1 282 ? 119.109 117.476 121.719 1.00 56.92  ? 356 ARG A C   1 
ATOM 1706 O O   . ARG A 1 282 ? 118.324 116.752 121.099 1.00 62.77  ? 356 ARG A O   1 
ATOM 1707 C CB  . ARG A 1 282 ? 118.482 118.224 124.013 1.00 54.71  ? 356 ARG A CB  1 
ATOM 1708 C CG  . ARG A 1 282 ? 117.939 119.303 124.927 1.00 60.95  ? 356 ARG A CG  1 
ATOM 1709 C CD  . ARG A 1 282 ? 118.949 120.408 125.146 1.00 59.83  ? 356 ARG A CD  1 
ATOM 1710 N NE  . ARG A 1 282 ? 120.128 119.933 125.857 1.00 57.10  ? 356 ARG A NE  1 
ATOM 1711 C CZ  . ARG A 1 282 ? 121.187 120.682 126.129 1.00 60.47  ? 356 ARG A CZ  1 
ATOM 1712 N NH1 . ARG A 1 282 ? 121.246 121.954 125.768 1.00 59.54  ? 356 ARG A NH1 1 
ATOM 1713 N NH2 . ARG A 1 282 ? 122.214 120.142 126.778 1.00 59.64  ? 356 ARG A NH2 1 
ATOM 1714 N N   . PRO A 1 283 ? 120.425 117.261 121.694 1.00 35.13  ? 357 PRO A N   1 
ATOM 1715 C CA  . PRO A 1 283 ? 120.974 116.135 120.930 1.00 35.09  ? 357 PRO A CA  1 
ATOM 1716 C C   . PRO A 1 283 ? 120.748 114.792 121.603 1.00 34.25  ? 357 PRO A C   1 
ATOM 1717 O O   . PRO A 1 283 ? 121.610 114.299 122.336 1.00 44.30  ? 357 PRO A O   1 
ATOM 1718 C CB  . PRO A 1 283 ? 122.466 116.475 120.836 1.00 33.88  ? 357 PRO A CB  1 
ATOM 1719 C CG  . PRO A 1 283 ? 122.723 117.347 122.003 1.00 34.99  ? 357 PRO A CG  1 
ATOM 1720 C CD  . PRO A 1 283 ? 121.483 118.157 122.188 1.00 37.94  ? 357 PRO A CD  1 
ATOM 1721 N N   . ILE A 1 284 ? 119.578 114.196 121.364 1.00 19.03  ? 358 ILE A N   1 
ATOM 1722 C CA  . ILE A 1 284 ? 119.249 112.916 121.977 1.00 25.62  ? 358 ILE A CA  1 
ATOM 1723 C C   . ILE A 1 284 ? 120.133 111.810 121.409 1.00 33.49  ? 358 ILE A C   1 
ATOM 1724 O O   . ILE A 1 284 ? 120.767 111.948 120.357 1.00 40.29  ? 358 ILE A O   1 
ATOM 1725 C CB  . ILE A 1 284 ? 117.764 112.586 121.770 1.00 30.34  ? 358 ILE A CB  1 
ATOM 1726 C CG1 . ILE A 1 284 ? 117.495 112.318 120.293 1.00 27.19  ? 358 ILE A CG1 1 
ATOM 1727 C CG2 . ILE A 1 284 ? 116.896 113.727 122.255 1.00 36.40  ? 358 ILE A CG2 1 
ATOM 1728 C CD1 . ILE A 1 284 ? 116.130 111.762 120.013 1.00 33.99  ? 358 ILE A CD1 1 
ATOM 1729 N N   . VAL A 1 285 ? 120.169 110.688 122.125 1.00 40.36  ? 359 VAL A N   1 
ATOM 1730 C CA  . VAL A 1 285 ? 120.843 109.479 121.672 1.00 29.31  ? 359 VAL A CA  1 
ATOM 1731 C C   . VAL A 1 285 ? 119.920 108.294 121.934 1.00 31.46  ? 359 VAL A C   1 
ATOM 1732 O O   . VAL A 1 285 ? 119.248 108.234 122.970 1.00 47.42  ? 359 VAL A O   1 
ATOM 1733 C CB  . VAL A 1 285 ? 122.216 109.295 122.354 1.00 17.97  ? 359 VAL A CB  1 
ATOM 1734 C CG1 . VAL A 1 285 ? 122.065 109.057 123.824 1.00 29.43  ? 359 VAL A CG1 1 
ATOM 1735 C CG2 . VAL A 1 285 ? 122.988 108.172 121.705 1.00 35.42  ? 359 VAL A CG2 1 
ATOM 1736 N N   . VAL A 1 286 ? 119.862 107.374 120.982 1.00 24.76  ? 360 VAL A N   1 
ATOM 1737 C CA  . VAL A 1 286 ? 118.862 106.310 120.975 1.00 17.42  ? 360 VAL A CA  1 
ATOM 1738 C C   . VAL A 1 286 ? 119.600 104.979 120.965 1.00 27.28  ? 360 VAL A C   1 
ATOM 1739 O O   . VAL A 1 286 ? 120.797 104.922 120.636 1.00 44.11  ? 360 VAL A O   1 
ATOM 1740 C CB  . VAL A 1 286 ? 117.896 106.442 119.775 1.00 31.07  ? 360 VAL A CB  1 
ATOM 1741 C CG1 . VAL A 1 286 ? 117.160 107.766 119.835 1.00 31.32  ? 360 VAL A CG1 1 
ATOM 1742 C CG2 . VAL A 1 286 ? 118.652 106.311 118.468 1.00 42.56  ? 360 VAL A CG2 1 
ATOM 1743 N N   . PRO A 1 287 ? 118.928 103.887 121.339 1.00 17.85  ? 361 PRO A N   1 
ATOM 1744 C CA  . PRO A 1 287 ? 119.603 102.584 121.367 1.00 26.28  ? 361 PRO A CA  1 
ATOM 1745 C C   . PRO A 1 287 ? 120.145 102.188 120.001 1.00 40.63  ? 361 PRO A C   1 
ATOM 1746 O O   . PRO A 1 287 ? 119.676 102.651 118.960 1.00 45.62  ? 361 PRO A O   1 
ATOM 1747 C CB  . PRO A 1 287 ? 118.501 101.625 121.827 1.00 26.10  ? 361 PRO A CB  1 
ATOM 1748 C CG  . PRO A 1 287 ? 117.578 102.472 122.597 1.00 32.45  ? 361 PRO A CG  1 
ATOM 1749 C CD  . PRO A 1 287 ? 117.576 103.805 121.918 1.00 25.53  ? 361 PRO A CD  1 
ATOM 1750 N N   . ALA A 1 288 ? 121.161 101.323 120.022 1.00 36.65  ? 362 ALA A N   1 
ATOM 1751 C CA  . ALA A 1 288 ? 121.874 100.979 118.797 1.00 29.99  ? 362 ALA A CA  1 
ATOM 1752 C C   . ALA A 1 288 ? 120.995 100.225 117.808 1.00 38.42  ? 362 ALA A C   1 
ATOM 1753 O O   . ALA A 1 288 ? 121.078 100.467 116.599 1.00 42.61  ? 362 ALA A O   1 
ATOM 1754 C CB  . ALA A 1 288 ? 123.116 100.153 119.130 1.00 40.11  ? 362 ALA A CB  1 
ATOM 1755 N N   . GLY A 1 289 ? 120.155 99.319  118.291 1.00 46.00  ? 363 GLY A N   1 
ATOM 1756 C CA  . GLY A 1 289 ? 119.413 98.424  117.430 1.00 47.52  ? 363 GLY A CA  1 
ATOM 1757 C C   . GLY A 1 289 ? 118.138 98.976  116.837 1.00 52.11  ? 363 GLY A C   1 
ATOM 1758 O O   . GLY A 1 289 ? 117.361 98.209  116.260 1.00 56.70  ? 363 GLY A O   1 
ATOM 1759 N N   . VAL A 1 290 ? 117.893 100.266 116.953 1.00 50.25  ? 364 VAL A N   1 
ATOM 1760 C CA  . VAL A 1 290 ? 116.654 100.860 116.469 1.00 47.81  ? 364 VAL A CA  1 
ATOM 1761 C C   . VAL A 1 290 ? 116.798 101.157 114.983 1.00 53.03  ? 364 VAL A C   1 
ATOM 1762 O O   . VAL A 1 290 ? 117.907 101.318 114.463 1.00 53.87  ? 364 VAL A O   1 
ATOM 1763 C CB  . VAL A 1 290 ? 116.304 102.128 117.278 1.00 47.84  ? 364 VAL A CB  1 
ATOM 1764 C CG1 . VAL A 1 290 ? 117.294 103.241 116.986 1.00 49.25  ? 364 VAL A CG1 1 
ATOM 1765 C CG2 . VAL A 1 290 ? 114.873 102.563 117.020 1.00 55.36  ? 364 VAL A CG2 1 
ATOM 1766 N N   . GLU A 1 291 ? 115.667 101.218 114.287 1.00 57.37  ? 365 GLU A N   1 
ATOM 1767 C CA  . GLU A 1 291 ? 115.626 101.513 112.861 1.00 54.92  ? 365 GLU A CA  1 
ATOM 1768 C C   . GLU A 1 291 ? 115.097 102.929 112.662 1.00 53.75  ? 365 GLU A C   1 
ATOM 1769 O O   . GLU A 1 291 ? 113.918 103.196 112.916 1.00 56.82  ? 365 GLU A O   1 
ATOM 1770 C CB  . GLU A 1 291 ? 114.747 100.497 112.131 1.00 55.55  ? 365 GLU A CB  1 
ATOM 1771 C CG  . GLU A 1 291 ? 115.009 100.377 110.639 1.00 61.34  ? 365 GLU A CG  1 
ATOM 1772 C CD  . GLU A 1 291 ? 114.378 101.497 109.837 1.00 65.82  ? 365 GLU A CD  1 
ATOM 1773 O OE1 . GLU A 1 291 ? 113.374 102.075 110.304 1.00 63.02  ? 365 GLU A OE1 1 
ATOM 1774 O OE2 . GLU A 1 291 ? 114.885 101.798 108.737 1.00 65.24  ? 365 GLU A OE2 1 
ATOM 1775 N N   . LEU A 1 292 ? 115.965 103.829 112.214 1.00 47.37  ? 366 LEU A N   1 
ATOM 1776 C CA  . LEU A 1 292 ? 115.592 105.206 111.927 1.00 48.04  ? 366 LEU A CA  1 
ATOM 1777 C C   . LEU A 1 292 ? 115.119 105.341 110.485 1.00 54.10  ? 366 LEU A C   1 
ATOM 1778 O O   . LEU A 1 292 ? 115.401 104.500 109.629 1.00 61.48  ? 366 LEU A O   1 
ATOM 1779 C CB  . LEU A 1 292 ? 116.759 106.164 112.175 1.00 43.59  ? 366 LEU A CB  1 
ATOM 1780 C CG  . LEU A 1 292 ? 117.342 106.289 113.580 1.00 50.13  ? 366 LEU A CG  1 
ATOM 1781 C CD1 . LEU A 1 292 ? 118.400 105.230 113.839 1.00 60.45  ? 366 LEU A CD1 1 
ATOM 1782 C CD2 . LEU A 1 292 ? 117.911 107.678 113.775 1.00 55.25  ? 366 LEU A CD2 1 
ATOM 1783 N N   . LYS A 1 293 ? 114.397 106.428 110.226 1.00 47.10  ? 367 LYS A N   1 
ATOM 1784 C CA  . LYS A 1 293 ? 113.886 106.714 108.891 1.00 43.29  ? 367 LYS A CA  1 
ATOM 1785 C C   . LYS A 1 293 ? 113.614 108.206 108.800 1.00 47.80  ? 367 LYS A C   1 
ATOM 1786 O O   . LYS A 1 293 ? 112.762 108.725 109.526 1.00 55.82  ? 367 LYS A O   1 
ATOM 1787 C CB  . LYS A 1 293 ? 112.620 105.908 108.604 1.00 46.29  ? 367 LYS A CB  1 
ATOM 1788 C CG  . LYS A 1 293 ? 112.101 106.036 107.190 1.00 46.12  ? 367 LYS A CG  1 
ATOM 1789 C CD  . LYS A 1 293 ? 110.924 105.106 106.966 1.00 49.15  ? 367 LYS A CD  1 
ATOM 1790 C CE  . LYS A 1 293 ? 110.408 105.198 105.542 1.00 53.96  ? 367 LYS A CE  1 
ATOM 1791 N NZ  . LYS A 1 293 ? 109.983 106.583 105.198 1.00 55.68  ? 367 LYS A NZ  1 
ATOM 1792 N N   . ILE A 1 294 ? 114.335 108.891 107.918 1.00 40.05  ? 368 ILE A N   1 
ATOM 1793 C CA  . ILE A 1 294 ? 114.259 110.340 107.778 1.00 39.87  ? 368 ILE A CA  1 
ATOM 1794 C C   . ILE A 1 294 ? 113.743 110.659 106.382 1.00 49.72  ? 368 ILE A C   1 
ATOM 1795 O O   . ILE A 1 294 ? 114.291 110.170 105.387 1.00 55.26  ? 368 ILE A O   1 
ATOM 1796 C CB  . ILE A 1 294 ? 115.628 111.000 108.025 1.00 29.05  ? 368 ILE A CB  1 
ATOM 1797 C CG1 . ILE A 1 294 ? 115.994 110.936 109.504 1.00 37.06  ? 368 ILE A CG1 1 
ATOM 1798 C CG2 . ILE A 1 294 ? 115.624 112.434 107.555 1.00 39.22  ? 368 ILE A CG2 1 
ATOM 1799 C CD1 . ILE A 1 294 ? 117.333 111.548 109.816 1.00 45.14  ? 368 ILE A CD1 1 
ATOM 1800 N N   . MET A 1 295 ? 112.692 111.473 106.309 1.00 56.19  ? 369 MET A N   1 
ATOM 1801 C CA  . MET A 1 295 ? 112.088 111.829 105.035 1.00 45.46  ? 369 MET A CA  1 
ATOM 1802 C C   . MET A 1 295 ? 111.488 113.222 105.136 1.00 47.12  ? 369 MET A C   1 
ATOM 1803 O O   . MET A 1 295 ? 111.101 113.668 106.218 1.00 53.74  ? 369 MET A O   1 
ATOM 1804 C CB  . MET A 1 295 ? 111.013 110.818 104.622 1.00 52.67  ? 369 MET A CB  1 
ATOM 1805 C CG  . MET A 1 295 ? 109.919 110.625 105.657 1.00 60.11  ? 369 MET A CG  1 
ATOM 1806 S SD  . MET A 1 295 ? 108.816 109.253 105.270 1.00 67.05  ? 369 MET A SD  1 
ATOM 1807 C CE  . MET A 1 295 ? 108.216 109.750 103.660 1.00 53.91  ? 369 MET A CE  1 
ATOM 1808 N N   . LEU A 1 296 ? 111.405 113.899 103.995 1.00 47.55  ? 370 LEU A N   1 
ATOM 1809 C CA  . LEU A 1 296 ? 110.897 115.263 103.966 1.00 53.29  ? 370 LEU A CA  1 
ATOM 1810 C C   . LEU A 1 296 ? 109.419 115.304 104.330 1.00 62.75  ? 370 LEU A C   1 
ATOM 1811 O O   . LEU A 1 296 ? 108.630 114.463 103.891 1.00 71.46  ? 370 LEU A O   1 
ATOM 1812 C CB  . LEU A 1 296 ? 111.105 115.881 102.586 1.00 52.98  ? 370 LEU A CB  1 
ATOM 1813 C CG  . LEU A 1 296 ? 112.536 116.256 102.203 1.00 58.59  ? 370 LEU A CG  1 
ATOM 1814 C CD1 . LEU A 1 296 ? 112.550 117.023 100.894 1.00 58.36  ? 370 LEU A CD1 1 
ATOM 1815 C CD2 . LEU A 1 296 ? 113.183 117.068 103.310 1.00 64.36  ? 370 LEU A CD2 1 
ATOM 1816 N N   . SER A 1 297 ? 109.051 116.288 105.142 1.00 62.38  ? 371 SER A N   1 
ATOM 1817 C CA  . SER A 1 297 ? 107.654 116.467 105.499 1.00 60.71  ? 371 SER A CA  1 
ATOM 1818 C C   . SER A 1 297 ? 106.859 116.924 104.278 1.00 65.98  ? 371 SER A C   1 
ATOM 1819 O O   . SER A 1 297 ? 107.353 117.730 103.483 1.00 67.58  ? 371 SER A O   1 
ATOM 1820 C CB  . SER A 1 297 ? 107.514 117.482 106.631 1.00 64.86  ? 371 SER A CB  1 
ATOM 1821 O OG  . SER A 1 297 ? 108.122 118.713 106.289 1.00 67.76  ? 371 SER A OG  1 
ATOM 1822 N N   . PRO A 1 298 ? 105.637 116.420 104.095 1.00 66.03  ? 372 PRO A N   1 
ATOM 1823 C CA  . PRO A 1 298 ? 104.871 116.783 102.891 1.00 62.76  ? 372 PRO A CA  1 
ATOM 1824 C C   . PRO A 1 298 ? 104.592 118.270 102.770 1.00 61.88  ? 372 PRO A C   1 
ATOM 1825 O O   . PRO A 1 298 ? 104.585 118.799 101.652 1.00 65.21  ? 372 PRO A O   1 
ATOM 1826 C CB  . PRO A 1 298 ? 103.576 115.974 103.047 1.00 68.51  ? 372 PRO A CB  1 
ATOM 1827 C CG  . PRO A 1 298 ? 103.474 115.696 104.511 1.00 69.45  ? 372 PRO A CG  1 
ATOM 1828 C CD  . PRO A 1 298 ? 104.881 115.530 104.989 1.00 66.02  ? 372 PRO A CD  1 
ATOM 1829 N N   . GLU A 1 299 ? 104.366 118.962 103.882 1.00 74.76  ? 373 GLU A N   1 
ATOM 1830 C CA  . GLU A 1 299 ? 104.109 120.399 103.858 1.00 79.70  ? 373 GLU A CA  1 
ATOM 1831 C C   . GLU A 1 299 ? 105.408 121.150 104.145 1.00 79.90  ? 373 GLU A C   1 
ATOM 1832 O O   . GLU A 1 299 ? 105.616 121.732 105.211 1.00 80.42  ? 373 GLU A O   1 
ATOM 1833 C CB  . GLU A 1 299 ? 103.012 120.758 104.857 1.00 80.90  ? 373 GLU A CB  1 
ATOM 1834 C CG  . GLU A 1 299 ? 102.481 122.179 104.724 1.00 82.85  ? 373 GLU A CG  1 
ATOM 1835 C CD  . GLU A 1 299 ? 101.628 122.375 103.484 1.00 84.23  ? 373 GLU A CD  1 
ATOM 1836 O OE1 . GLU A 1 299 ? 101.159 121.367 102.915 1.00 85.34  ? 373 GLU A OE1 1 
ATOM 1837 O OE2 . GLU A 1 299 ? 101.427 123.540 103.079 1.00 83.03  ? 373 GLU A OE2 1 
ATOM 1838 N N   . ALA A 1 300 ? 106.298 121.121 103.156 1.00 65.30  ? 374 ALA A N   1 
ATOM 1839 C CA  . ALA A 1 300 ? 107.605 121.754 103.288 1.00 62.37  ? 374 ALA A CA  1 
ATOM 1840 C C   . ALA A 1 300 ? 108.083 122.203 101.919 1.00 64.28  ? 374 ALA A C   1 
ATOM 1841 O O   . ALA A 1 300 ? 108.157 121.393 100.991 1.00 62.01  ? 374 ALA A O   1 
ATOM 1842 C CB  . ALA A 1 300 ? 108.617 120.798 103.919 1.00 66.73  ? 374 ALA A CB  1 
ATOM 1843 N N   . ARG A 1 301 ? 108.407 123.486 101.800 1.00 76.88  ? 375 ARG A N   1 
ATOM 1844 C CA  . ARG A 1 301 ? 108.981 124.012 100.574 1.00 80.83  ? 375 ARG A CA  1 
ATOM 1845 C C   . ARG A 1 301 ? 110.476 123.711 100.521 1.00 81.44  ? 375 ARG A C   1 
ATOM 1846 O O   . ARG A 1 301 ? 111.126 123.483 101.545 1.00 84.07  ? 375 ARG A O   1 
ATOM 1847 C CB  . ARG A 1 301 ? 108.739 125.519 100.464 1.00 80.74  ? 375 ARG A CB  1 
ATOM 1848 C CG  . ARG A 1 301 ? 107.340 125.900 99.998  1.00 80.20  ? 375 ARG A CG  1 
ATOM 1849 C CD  . ARG A 1 301 ? 106.334 125.879 101.140 1.00 83.32  ? 375 ARG A CD  1 
ATOM 1850 N NE  . ARG A 1 301 ? 106.629 126.889 102.150 1.00 84.41  ? 375 ARG A NE  1 
ATOM 1851 C CZ  . ARG A 1 301 ? 106.077 126.926 103.355 1.00 82.32  ? 375 ARG A CZ  1 
ATOM 1852 N NH1 . ARG A 1 301 ? 105.192 126.020 103.739 1.00 80.28  ? 375 ARG A NH1 1 
ATOM 1853 N NH2 . ARG A 1 301 ? 106.421 127.897 104.197 1.00 81.83  ? 375 ARG A NH2 1 
ATOM 1854 N N   . ASN A 1 302 ? 111.011 123.700 99.297  1.00 72.91  ? 376 ASN A N   1 
ATOM 1855 C CA  . ASN A 1 302 ? 112.420 123.424 99.028  1.00 68.93  ? 376 ASN A CA  1 
ATOM 1856 C C   . ASN A 1 302 ? 112.793 121.998 99.420  1.00 65.01  ? 376 ASN A C   1 
ATOM 1857 O O   . ASN A 1 302 ? 112.027 121.309 100.101 1.00 69.33  ? 376 ASN A O   1 
ATOM 1858 C CB  . ASN A 1 302 ? 113.319 124.435 99.748  1.00 68.93  ? 376 ASN A CB  1 
ATOM 1859 C CG  . ASN A 1 302 ? 114.678 124.580 99.090  1.00 75.50  ? 376 ASN A CG  1 
ATOM 1860 O OD1 . ASN A 1 302 ? 115.644 123.926 99.481  1.00 74.62  ? 376 ASN A OD1 1 
ATOM 1861 N ND2 . ASN A 1 302 ? 114.758 125.442 98.083  1.00 76.77  ? 376 ASN A ND2 1 
ATOM 1862 N N   . THR A 1 303 ? 113.959 121.540 98.983  1.00 53.05  ? 377 THR A N   1 
ATOM 1863 C CA  . THR A 1 303 ? 114.419 120.186 99.240  1.00 53.54  ? 377 THR A CA  1 
ATOM 1864 C C   . THR A 1 303 ? 115.680 120.211 100.092 1.00 61.15  ? 377 THR A C   1 
ATOM 1865 O O   . THR A 1 303 ? 116.246 121.267 100.383 1.00 67.40  ? 377 THR A O   1 
ATOM 1866 C CB  . THR A 1 303 ? 114.678 119.440 97.928  1.00 60.36  ? 377 THR A CB  1 
ATOM 1867 O OG1 . THR A 1 303 ? 115.658 120.147 97.160  1.00 62.52  ? 377 THR A OG1 1 
ATOM 1868 C CG2 . THR A 1 303 ? 113.396 119.329 97.124  1.00 62.38  ? 377 THR A CG2 1 
ATOM 1869 N N   . ALA A 1 304 ? 116.116 119.022 100.493 1.00 63.11  ? 378 ALA A N   1 
ATOM 1870 C CA  . ALA A 1 304 ? 117.266 118.852 101.366 1.00 59.90  ? 378 ALA A CA  1 
ATOM 1871 C C   . ALA A 1 304 ? 118.294 117.945 100.704 1.00 54.11  ? 378 ALA A C   1 
ATOM 1872 O O   . ALA A 1 304 ? 117.983 117.158 99.808  1.00 60.55  ? 378 ALA A O   1 
ATOM 1873 C CB  . ALA A 1 304 ? 116.846 118.279 102.725 1.00 58.45  ? 378 ALA A CB  1 
ATOM 1874 N N   . TRP A 1 305 ? 119.535 118.068 101.161 1.00 44.30  ? 379 TRP A N   1 
ATOM 1875 C CA  . TRP A 1 305 ? 120.653 117.304 100.635 1.00 52.05  ? 379 TRP A CA  1 
ATOM 1876 C C   . TRP A 1 305 ? 121.234 116.428 101.735 1.00 55.51  ? 379 TRP A C   1 
ATOM 1877 O O   . TRP A 1 305 ? 121.252 116.810 102.908 1.00 66.15  ? 379 TRP A O   1 
ATOM 1878 C CB  . TRP A 1 305 ? 121.737 118.231 100.076 1.00 58.44  ? 379 TRP A CB  1 
ATOM 1879 C CG  . TRP A 1 305 ? 121.299 119.014 98.874  1.00 60.86  ? 379 TRP A CG  1 
ATOM 1880 C CD1 . TRP A 1 305 ? 120.609 120.187 98.873  1.00 56.23  ? 379 TRP A CD1 1 
ATOM 1881 C CD2 . TRP A 1 305 ? 121.533 118.686 97.500  1.00 50.57  ? 379 TRP A CD2 1 
ATOM 1882 N NE1 . TRP A 1 305 ? 120.393 120.609 97.586  1.00 55.66  ? 379 TRP A NE1 1 
ATOM 1883 C CE2 . TRP A 1 305 ? 120.951 119.704 96.724  1.00 48.31  ? 379 TRP A CE2 1 
ATOM 1884 C CE3 . TRP A 1 305 ? 122.178 117.630 96.852  1.00 47.27  ? 379 TRP A CE3 1 
ATOM 1885 C CZ2 . TRP A 1 305 ? 120.993 119.697 95.334  1.00 53.98  ? 379 TRP A CZ2 1 
ATOM 1886 C CZ3 . TRP A 1 305 ? 122.217 117.624 95.472  1.00 54.61  ? 379 TRP A CZ3 1 
ATOM 1887 C CH2 . TRP A 1 305 ? 121.629 118.651 94.728  1.00 58.14  ? 379 TRP A CH2 1 
ATOM 1888 N N   . VAL A 1 306 ? 121.712 115.247 101.350 1.00 32.99  ? 380 VAL A N   1 
ATOM 1889 C CA  . VAL A 1 306 ? 122.255 114.274 102.288 1.00 22.43  ? 380 VAL A CA  1 
ATOM 1890 C C   . VAL A 1 306 ? 123.721 114.038 101.958 1.00 34.96  ? 380 VAL A C   1 
ATOM 1891 O O   . VAL A 1 306 ? 124.099 113.947 100.784 1.00 51.51  ? 380 VAL A O   1 
ATOM 1892 C CB  . VAL A 1 306 ? 121.461 112.951 102.268 1.00 29.09  ? 380 VAL A CB  1 
ATOM 1893 C CG1 . VAL A 1 306 ? 121.484 112.319 100.891 1.00 36.53  ? 380 VAL A CG1 1 
ATOM 1894 C CG2 . VAL A 1 306 ? 121.996 111.989 103.312 1.00 40.33  ? 380 VAL A CG2 1 
ATOM 1895 N N   . SER A 1 307 ? 124.551 113.961 102.996 1.00 39.24  ? 381 SER A N   1 
ATOM 1896 C CA  . SER A 1 307 ? 125.972 113.693 102.847 1.00 42.71  ? 381 SER A CA  1 
ATOM 1897 C C   . SER A 1 307 ? 126.363 112.520 103.731 1.00 43.59  ? 381 SER A C   1 
ATOM 1898 O O   . SER A 1 307 ? 125.783 112.307 104.799 1.00 53.10  ? 381 SER A O   1 
ATOM 1899 C CB  . SER A 1 307 ? 126.812 114.921 103.205 1.00 47.53  ? 381 SER A CB  1 
ATOM 1900 O OG  . SER A 1 307 ? 126.613 115.296 104.555 1.00 48.94  ? 381 SER A OG  1 
ATOM 1901 N N   . PHE A 1 308 ? 127.360 111.760 103.279 1.00 40.04  ? 382 PHE A N   1 
ATOM 1902 C CA  . PHE A 1 308 ? 127.824 110.556 103.972 1.00 45.06  ? 382 PHE A CA  1 
ATOM 1903 C C   . PHE A 1 308 ? 129.318 110.697 104.246 1.00 48.07  ? 382 PHE A C   1 
ATOM 1904 O O   . PHE A 1 308 ? 130.138 110.369 103.387 1.00 51.68  ? 382 PHE A O   1 
ATOM 1905 C CB  . PHE A 1 308 ? 127.526 109.312 103.150 1.00 44.57  ? 382 PHE A CB  1 
ATOM 1906 C CG  . PHE A 1 308 ? 126.120 109.247 102.637 1.00 45.70  ? 382 PHE A CG  1 
ATOM 1907 C CD1 . PHE A 1 308 ? 125.119 108.675 103.397 1.00 41.68  ? 382 PHE A CD1 1 
ATOM 1908 C CD2 . PHE A 1 308 ? 125.800 109.751 101.390 1.00 48.05  ? 382 PHE A CD2 1 
ATOM 1909 C CE1 . PHE A 1 308 ? 123.828 108.613 102.928 1.00 44.75  ? 382 PHE A CE1 1 
ATOM 1910 C CE2 . PHE A 1 308 ? 124.508 109.690 100.916 1.00 49.35  ? 382 PHE A CE2 1 
ATOM 1911 C CZ  . PHE A 1 308 ? 123.522 109.121 101.687 1.00 50.98  ? 382 PHE A CZ  1 
ATOM 1912 N N   . ASP A 1 309 ? 129.664 111.166 105.445 1.00 51.00  ? 383 ASP A N   1 
ATOM 1913 C CA  . ASP A 1 309 ? 131.059 111.346 105.851 1.00 51.81  ? 383 ASP A CA  1 
ATOM 1914 C C   . ASP A 1 309 ? 131.811 112.254 104.882 1.00 59.80  ? 383 ASP A C   1 
ATOM 1915 O O   . ASP A 1 309 ? 132.959 111.993 104.515 1.00 63.31  ? 383 ASP A O   1 
ATOM 1916 C CB  . ASP A 1 309 ? 131.775 110.001 105.990 1.00 56.34  ? 383 ASP A CB  1 
ATOM 1917 C CG  . ASP A 1 309 ? 131.241 109.171 107.133 1.00 61.85  ? 383 ASP A CG  1 
ATOM 1918 O OD1 . ASP A 1 309 ? 130.848 109.756 108.163 1.00 61.09  ? 383 ASP A OD1 1 
ATOM 1919 O OD2 . ASP A 1 309 ? 131.227 107.929 107.006 1.00 65.82  ? 383 ASP A OD2 1 
ATOM 1920 N N   . GLY A 1 310 ? 131.163 113.336 104.468 1.00 49.90  ? 384 GLY A N   1 
ATOM 1921 C CA  . GLY A 1 310 ? 131.775 114.241 103.511 1.00 47.40  ? 384 GLY A CA  1 
ATOM 1922 C C   . GLY A 1 310 ? 132.003 113.621 102.150 1.00 50.90  ? 384 GLY A C   1 
ATOM 1923 O O   . GLY A 1 310 ? 133.060 113.833 101.544 1.00 56.45  ? 384 GLY A O   1 
ATOM 1924 N N   . ARG A 1 311 ? 131.031 112.860 101.655 1.00 48.69  ? 385 ARG A N   1 
ATOM 1925 C CA  . ARG A 1 311 ? 131.125 112.206 100.357 1.00 45.38  ? 385 ARG A CA  1 
ATOM 1926 C C   . ARG A 1 311 ? 129.925 112.597 99.511  1.00 48.45  ? 385 ARG A C   1 
ATOM 1927 O O   . ARG A 1 311 ? 129.218 113.551 99.849  1.00 55.70  ? 385 ARG A O   1 
ATOM 1928 C CB  . ARG A 1 311 ? 131.215 110.688 100.507 1.00 45.20  ? 385 ARG A CB  1 
ATOM 1929 C CG  . ARG A 1 311 ? 132.475 110.221 101.214 1.00 51.72  ? 385 ARG A CG  1 
ATOM 1930 C CD  . ARG A 1 311 ? 133.245 109.212 100.376 1.00 51.39  ? 385 ARG A CD  1 
ATOM 1931 N NE  . ARG A 1 311 ? 132.403 108.114 99.918  1.00 53.22  ? 385 ARG A NE  1 
ATOM 1932 C CZ  . ARG A 1 311 ? 132.079 107.062 100.657 1.00 53.97  ? 385 ARG A CZ  1 
ATOM 1933 N NH1 . ARG A 1 311 ? 132.511 106.931 101.900 1.00 54.81  ? 385 ARG A NH1 1 
ATOM 1934 N NH2 . ARG A 1 311 ? 131.306 106.115 100.134 1.00 50.23  ? 385 ARG A NH2 1 
ATOM 1935 N N   . LYS A 1 312 ? 129.721 111.887 98.401  1.00 48.33  ? 386 LYS A N   1 
ATOM 1936 C CA  . LYS A 1 312 ? 128.725 112.228 97.390  1.00 54.54  ? 386 LYS A CA  1 
ATOM 1937 C C   . LYS A 1 312 ? 127.437 112.775 97.996  1.00 58.53  ? 386 LYS A C   1 
ATOM 1938 O O   . LYS A 1 312 ? 126.830 112.157 98.874  1.00 63.92  ? 386 LYS A O   1 
ATOM 1939 C CB  . LYS A 1 312 ? 128.435 110.992 96.529  1.00 58.66  ? 386 LYS A CB  1 
ATOM 1940 C CG  . LYS A 1 312 ? 127.802 109.818 97.267  1.00 56.85  ? 386 LYS A CG  1 
ATOM 1941 C CD  . LYS A 1 312 ? 127.658 108.606 96.359  1.00 62.53  ? 386 LYS A CD  1 
ATOM 1942 C CE  . LYS A 1 312 ? 126.573 108.816 95.314  1.00 64.44  ? 386 LYS A CE  1 
ATOM 1943 N NZ  . LYS A 1 312 ? 126.358 107.596 94.486  1.00 61.38  ? 386 LYS A NZ  1 
ATOM 1944 N N   . ARG A 1 313 ? 127.053 113.965 97.546  1.00 46.03  ? 387 ARG A N   1 
ATOM 1945 C CA  . ARG A 1 313 ? 125.840 114.629 98.000  1.00 32.71  ? 387 ARG A CA  1 
ATOM 1946 C C   . ARG A 1 313 ? 124.754 114.453 96.953  1.00 39.88  ? 387 ARG A C   1 
ATOM 1947 O O   . ARG A 1 313 ? 124.970 114.741 95.771  1.00 53.28  ? 387 ARG A O   1 
ATOM 1948 C CB  . ARG A 1 313 ? 126.081 116.115 98.252  1.00 34.09  ? 387 ARG A CB  1 
ATOM 1949 C CG  . ARG A 1 313 ? 127.125 116.409 99.297  1.00 38.49  ? 387 ARG A CG  1 
ATOM 1950 C CD  . ARG A 1 313 ? 127.409 117.894 99.356  1.00 41.39  ? 387 ARG A CD  1 
ATOM 1951 N NE  . ARG A 1 313 ? 126.186 118.667 99.532  1.00 41.84  ? 387 ARG A NE  1 
ATOM 1952 C CZ  . ARG A 1 313 ? 126.146 119.986 99.642  1.00 45.21  ? 387 ARG A CZ  1 
ATOM 1953 N NH1 . ARG A 1 313 ? 127.246 120.718 99.585  1.00 48.33  ? 387 ARG A NH1 1 
ATOM 1954 N NH2 . ARG A 1 313 ? 124.973 120.587 99.816  1.00 41.71  ? 387 ARG A NH2 1 
ATOM 1955 N N   . GLN A 1 314 ? 123.593 113.982 97.387  1.00 38.12  ? 388 GLN A N   1 
ATOM 1956 C CA  . GLN A 1 314 ? 122.473 113.757 96.493  1.00 49.39  ? 388 GLN A CA  1 
ATOM 1957 C C   . GLN A 1 314 ? 121.217 114.331 97.124  1.00 58.19  ? 388 GLN A C   1 
ATOM 1958 O O   . GLN A 1 314 ? 120.992 114.184 98.328  1.00 62.36  ? 388 GLN A O   1 
ATOM 1959 C CB  . GLN A 1 314 ? 122.311 112.263 96.176  1.00 51.35  ? 388 GLN A CB  1 
ATOM 1960 C CG  . GLN A 1 314 ? 121.993 111.387 97.368  1.00 50.63  ? 388 GLN A CG  1 
ATOM 1961 C CD  . GLN A 1 314 ? 121.930 109.920 97.005  1.00 51.50  ? 388 GLN A CD  1 
ATOM 1962 O OE1 . GLN A 1 314 ? 122.070 109.550 95.840  1.00 53.50  ? 388 GLN A OE1 1 
ATOM 1963 N NE2 . GLN A 1 314 ? 121.724 109.072 98.005  1.00 58.38  ? 388 GLN A NE2 1 
ATOM 1964 N N   . GLU A 1 315 ? 120.417 115.008 96.309  1.00 54.17  ? 389 GLU A N   1 
ATOM 1965 C CA  . GLU A 1 315 ? 119.233 115.685 96.809  1.00 54.53  ? 389 GLU A CA  1 
ATOM 1966 C C   . GLU A 1 315 ? 118.108 114.691 97.054  1.00 56.85  ? 389 GLU A C   1 
ATOM 1967 O O   . GLU A 1 315 ? 117.898 113.759 96.273  1.00 57.95  ? 389 GLU A O   1 
ATOM 1968 C CB  . GLU A 1 315 ? 118.781 116.762 95.826  1.00 56.91  ? 389 GLU A CB  1 
ATOM 1969 C CG  . GLU A 1 315 ? 118.661 116.281 94.391  1.00 63.23  ? 389 GLU A CG  1 
ATOM 1970 C CD  . GLU A 1 315 ? 118.368 117.410 93.423  1.00 67.41  ? 389 GLU A CD  1 
ATOM 1971 O OE1 . GLU A 1 315 ? 118.172 118.554 93.883  1.00 67.20  ? 389 GLU A OE1 1 
ATOM 1972 O OE2 . GLU A 1 315 ? 118.336 117.153 92.201  1.00 66.80  ? 389 GLU A OE2 1 
ATOM 1973 N N   . ILE A 1 316 ? 117.391 114.892 98.155  1.00 49.98  ? 390 ILE A N   1 
ATOM 1974 C CA  . ILE A 1 316 ? 116.215 114.105 98.493  1.00 50.38  ? 390 ILE A CA  1 
ATOM 1975 C C   . ILE A 1 316 ? 115.000 115.018 98.418  1.00 65.12  ? 390 ILE A C   1 
ATOM 1976 O O   . ILE A 1 316 ? 115.040 116.160 98.892  1.00 68.02  ? 390 ILE A O   1 
ATOM 1977 C CB  . ILE A 1 316 ? 116.348 113.443 99.876  1.00 50.58  ? 390 ILE A CB  1 
ATOM 1978 C CG1 . ILE A 1 316 ? 116.510 114.491 100.977 1.00 56.24  ? 390 ILE A CG1 1 
ATOM 1979 C CG2 . ILE A 1 316 ? 117.520 112.475 99.889  1.00 60.07  ? 390 ILE A CG2 1 
ATOM 1980 C CD1 . ILE A 1 316 ? 116.417 113.921 102.371 1.00 60.56  ? 390 ILE A CD1 1 
ATOM 1981 N N   . ARG A 1 317 ? 113.937 114.527 97.796  1.00 65.96  ? 391 ARG A N   1 
ATOM 1982 C CA  . ARG A 1 317 ? 112.721 115.282 97.553  1.00 54.96  ? 391 ARG A CA  1 
ATOM 1983 C C   . ARG A 1 317 ? 111.551 114.606 98.264  1.00 62.14  ? 391 ARG A C   1 
ATOM 1984 O O   . ARG A 1 317 ? 111.734 113.695 99.080  1.00 66.38  ? 391 ARG A O   1 
ATOM 1985 C CB  . ARG A 1 317 ? 112.490 115.430 96.048  1.00 50.26  ? 391 ARG A CB  1 
ATOM 1986 C CG  . ARG A 1 317 ? 112.555 114.128 95.279  1.00 56.10  ? 391 ARG A CG  1 
ATOM 1987 C CD  . ARG A 1 317 ? 112.556 114.378 93.784  1.00 58.44  ? 391 ARG A CD  1 
ATOM 1988 N NE  . ARG A 1 317 ? 113.699 115.182 93.371  1.00 55.52  ? 391 ARG A NE  1 
ATOM 1989 C CZ  . ARG A 1 317 ? 114.880 114.683 93.033  1.00 58.51  ? 391 ARG A CZ  1 
ATOM 1990 N NH1 . ARG A 1 317 ? 115.112 113.382 93.050  1.00 56.06  ? 391 ARG A NH1 1 
ATOM 1991 N NH2 . ARG A 1 317 ? 115.854 115.511 92.668  1.00 61.04  ? 391 ARG A NH2 1 
ATOM 1992 N N   . HIS A 1 318 ? 110.338 115.064 97.959  1.00 65.30  ? 392 HIS A N   1 
ATOM 1993 C CA  . HIS A 1 318 ? 109.142 114.677 98.701  1.00 66.74  ? 392 HIS A CA  1 
ATOM 1994 C C   . HIS A 1 318 ? 108.831 113.185 98.646  1.00 69.10  ? 392 HIS A C   1 
ATOM 1995 O O   . HIS A 1 318 ? 107.862 112.734 99.265  1.00 77.36  ? 392 HIS A O   1 
ATOM 1996 C CB  . HIS A 1 318 ? 107.937 115.463 98.183  1.00 68.74  ? 392 HIS A CB  1 
ATOM 1997 C CG  . HIS A 1 318 ? 107.984 116.922 98.506  1.00 74.37  ? 392 HIS A CG  1 
ATOM 1998 N ND1 . HIS A 1 318 ? 107.091 117.830 97.980  1.00 76.95  ? 392 HIS A ND1 1 
ATOM 1999 C CD2 . HIS A 1 318 ? 108.817 117.633 99.302  1.00 77.32  ? 392 HIS A CD2 1 
ATOM 2000 C CE1 . HIS A 1 318 ? 107.371 119.037 98.437  1.00 76.80  ? 392 HIS A CE1 1 
ATOM 2001 N NE2 . HIS A 1 318 ? 108.415 118.945 99.242  1.00 78.13  ? 392 HIS A NE2 1 
ATOM 2002 N N   . GLY A 1 319 ? 109.628 112.407 97.920  1.00 55.37  ? 393 GLY A N   1 
ATOM 2003 C CA  . GLY A 1 319 ? 109.366 110.986 97.811  1.00 56.26  ? 393 GLY A CA  1 
ATOM 2004 C C   . GLY A 1 319 ? 110.477 110.101 98.337  1.00 56.40  ? 393 GLY A C   1 
ATOM 2005 O O   . GLY A 1 319 ? 110.252 108.926 98.642  1.00 58.08  ? 393 GLY A O   1 
ATOM 2006 N N   . ASP A 1 320 ? 111.678 110.651 98.450  1.00 57.81  ? 394 ASP A N   1 
ATOM 2007 C CA  . ASP A 1 320 ? 112.837 109.884 98.876  1.00 54.21  ? 394 ASP A CA  1 
ATOM 2008 C C   . ASP A 1 320 ? 112.882 109.768 100.394 1.00 57.60  ? 394 ASP A C   1 
ATOM 2009 O O   . ASP A 1 320 ? 112.489 110.683 101.120 1.00 65.07  ? 394 ASP A O   1 
ATOM 2010 C CB  . ASP A 1 320 ? 114.123 110.534 98.365  1.00 59.97  ? 394 ASP A CB  1 
ATOM 2011 C CG  . ASP A 1 320 ? 114.091 110.785 96.873  1.00 64.99  ? 394 ASP A CG  1 
ATOM 2012 O OD1 . ASP A 1 320 ? 113.313 110.103 96.174  1.00 65.49  ? 394 ASP A OD1 1 
ATOM 2013 O OD2 . ASP A 1 320 ? 114.840 111.665 96.399  1.00 67.72  ? 394 ASP A OD2 1 
ATOM 2014 N N   . SER A 1 321 ? 113.370 108.623 100.866 1.00 48.83  ? 395 SER A N   1 
ATOM 2015 C CA  . SER A 1 321 ? 113.509 108.370 102.291 1.00 51.43  ? 395 SER A CA  1 
ATOM 2016 C C   . SER A 1 321 ? 114.825 107.656 102.553 1.00 51.47  ? 395 SER A C   1 
ATOM 2017 O O   . SER A 1 321 ? 115.234 106.779 101.788 1.00 53.05  ? 395 SER A O   1 
ATOM 2018 C CB  . SER A 1 321 ? 112.344 107.535 102.832 1.00 56.63  ? 395 SER A CB  1 
ATOM 2019 O OG  . SER A 1 321 ? 112.508 107.276 104.214 1.00 59.15  ? 395 SER A OG  1 
ATOM 2020 N N   . ILE A 1 322 ? 115.484 108.037 103.644 1.00 47.90  ? 396 ILE A N   1 
ATOM 2021 C CA  . ILE A 1 322 ? 116.734 107.421 104.071 1.00 45.48  ? 396 ILE A CA  1 
ATOM 2022 C C   . ILE A 1 322 ? 116.474 106.652 105.360 1.00 46.94  ? 396 ILE A C   1 
ATOM 2023 O O   . ILE A 1 322 ? 115.816 107.162 106.274 1.00 52.88  ? 396 ILE A O   1 
ATOM 2024 C CB  . ILE A 1 322 ? 117.860 108.463 104.240 1.00 38.53  ? 396 ILE A CB  1 
ATOM 2025 C CG1 . ILE A 1 322 ? 119.202 107.769 104.478 1.00 53.18  ? 396 ILE A CG1 1 
ATOM 2026 C CG2 . ILE A 1 322 ? 117.554 109.460 105.338 1.00 43.94  ? 396 ILE A CG2 1 
ATOM 2027 C CD1 . ILE A 1 322 ? 120.397 108.686 104.333 1.00 54.74  ? 396 ILE A CD1 1 
ATOM 2028 N N   . SER A 1 323 ? 116.950 105.411 105.412 1.00 46.69  ? 397 SER A N   1 
ATOM 2029 C CA  . SER A 1 323 ? 116.759 104.532 106.558 1.00 49.14  ? 397 SER A CA  1 
ATOM 2030 C C   . SER A 1 323 ? 118.112 104.196 107.166 1.00 52.97  ? 397 SER A C   1 
ATOM 2031 O O   . SER A 1 323 ? 119.021 103.757 106.456 1.00 55.77  ? 397 SER A O   1 
ATOM 2032 C CB  . SER A 1 323 ? 116.032 103.250 106.151 1.00 55.52  ? 397 SER A CB  1 
ATOM 2033 O OG  . SER A 1 323 ? 116.769 102.535 105.176 1.00 62.45  ? 397 SER A OG  1 
ATOM 2034 N N   . ILE A 1 324 ? 118.235 104.381 108.478 1.00 47.17  ? 398 ILE A N   1 
ATOM 2035 C CA  . ILE A 1 324 ? 119.506 104.261 109.184 1.00 41.43  ? 398 ILE A CA  1 
ATOM 2036 C C   . ILE A 1 324 ? 119.394 103.155 110.221 1.00 46.95  ? 398 ILE A C   1 
ATOM 2037 O O   . ILE A 1 324 ? 118.427 103.111 110.989 1.00 54.14  ? 398 ILE A O   1 
ATOM 2038 C CB  . ILE A 1 324 ? 119.910 105.590 109.845 1.00 39.69  ? 398 ILE A CB  1 
ATOM 2039 C CG1 . ILE A 1 324 ? 119.774 106.738 108.849 1.00 49.62  ? 398 ILE A CG1 1 
ATOM 2040 C CG2 . ILE A 1 324 ? 121.328 105.509 110.366 1.00 54.36  ? 398 ILE A CG2 1 
ATOM 2041 C CD1 . ILE A 1 324 ? 120.042 108.091 109.444 1.00 50.82  ? 398 ILE A CD1 1 
ATOM 2042 N N   . THR A 1 325 ? 120.382 102.263 110.237 1.00 48.92  ? 399 THR A N   1 
ATOM 2043 C CA  . THR A 1 325 ? 120.420 101.140 111.161 1.00 51.30  ? 399 THR A CA  1 
ATOM 2044 C C   . THR A 1 325 ? 121.878 100.807 111.441 1.00 47.59  ? 399 THR A C   1 
ATOM 2045 O O   . THR A 1 325 ? 122.725 100.935 110.553 1.00 50.55  ? 399 THR A O   1 
ATOM 2046 C CB  . THR A 1 325 ? 119.690 99.921  110.581 1.00 58.82  ? 399 THR A CB  1 
ATOM 2047 O OG1 . THR A 1 325 ? 118.326 100.264 110.311 1.00 60.44  ? 399 THR A OG1 1 
ATOM 2048 C CG2 . THR A 1 325 ? 119.719 98.752  111.555 1.00 57.36  ? 399 THR A CG2 1 
ATOM 2049 N N   . THR A 1 326 ? 122.170 100.394 112.673 1.00 45.09  ? 400 THR A N   1 
ATOM 2050 C CA  . THR A 1 326 ? 123.534 100.023 113.023 1.00 49.23  ? 400 THR A CA  1 
ATOM 2051 C C   . THR A 1 326 ? 123.971 98.804  112.222 1.00 56.41  ? 400 THR A C   1 
ATOM 2052 O O   . THR A 1 326 ? 123.257 97.799  112.155 1.00 56.70  ? 400 THR A O   1 
ATOM 2053 C CB  . THR A 1 326 ? 123.643 99.742  114.521 1.00 42.91  ? 400 THR A CB  1 
ATOM 2054 O OG1 . THR A 1 326 ? 123.292 100.919 115.256 1.00 49.98  ? 400 THR A OG1 1 
ATOM 2055 C CG2 . THR A 1 326 ? 125.058 99.335  114.886 1.00 43.96  ? 400 THR A CG2 1 
ATOM 2056 N N   . SER A 1 327 ? 125.150 98.897  111.612 1.00 57.54  ? 401 SER A N   1 
ATOM 2057 C CA  . SER A 1 327 ? 125.647 97.831  110.759 1.00 50.30  ? 401 SER A CA  1 
ATOM 2058 C C   . SER A 1 327 ? 126.141 96.651  111.589 1.00 53.03  ? 401 SER A C   1 
ATOM 2059 O O   . SER A 1 327 ? 126.497 96.782  112.763 1.00 53.56  ? 401 SER A O   1 
ATOM 2060 C CB  . SER A 1 327 ? 126.774 98.344  109.863 1.00 53.56  ? 401 SER A CB  1 
ATOM 2061 O OG  . SER A 1 327 ? 127.263 97.315  109.019 1.00 59.39  ? 401 SER A OG  1 
ATOM 2062 N N   . THR A 1 328 ? 126.159 95.482  110.955 1.00 61.78  ? 402 THR A N   1 
ATOM 2063 C CA  . THR A 1 328 ? 126.673 94.263  111.561 1.00 60.89  ? 402 THR A CA  1 
ATOM 2064 C C   . THR A 1 328 ? 128.148 94.038  111.258 1.00 61.14  ? 402 THR A C   1 
ATOM 2065 O O   . THR A 1 328 ? 128.699 93.006  111.654 1.00 59.92  ? 402 THR A O   1 
ATOM 2066 C CB  . THR A 1 328 ? 125.860 93.056  111.091 1.00 66.10  ? 402 THR A CB  1 
ATOM 2067 O OG1 . THR A 1 328 ? 125.932 92.958  109.664 1.00 64.82  ? 402 THR A OG1 1 
ATOM 2068 C CG2 . THR A 1 328 ? 124.406 93.198  111.511 1.00 64.05  ? 402 THR A CG2 1 
ATOM 2069 N N   . TYR A 1 329 ? 128.795 94.979  110.569 1.00 61.94  ? 403 TYR A N   1 
ATOM 2070 C CA  . TYR A 1 329 ? 130.200 94.871  110.178 1.00 60.79  ? 403 TYR A CA  1 
ATOM 2071 C C   . TYR A 1 329 ? 130.958 96.038  110.795 1.00 66.72  ? 403 TYR A C   1 
ATOM 2072 O O   . TYR A 1 329 ? 131.097 97.102  110.171 1.00 68.60  ? 403 TYR A O   1 
ATOM 2073 C CB  . TYR A 1 329 ? 130.345 94.864  108.659 1.00 56.70  ? 403 TYR A CB  1 
ATOM 2074 C CG  . TYR A 1 329 ? 129.581 93.755  107.977 1.00 58.97  ? 403 TYR A CG  1 
ATOM 2075 C CD1 . TYR A 1 329 ? 130.088 92.465  107.930 1.00 64.39  ? 403 TYR A CD1 1 
ATOM 2076 C CD2 . TYR A 1 329 ? 128.355 93.999  107.378 1.00 63.17  ? 403 TYR A CD2 1 
ATOM 2077 C CE1 . TYR A 1 329 ? 129.393 91.448  107.308 1.00 65.43  ? 403 TYR A CE1 1 
ATOM 2078 C CE2 . TYR A 1 329 ? 127.653 92.989  106.753 1.00 68.28  ? 403 TYR A CE2 1 
ATOM 2079 C CZ  . TYR A 1 329 ? 128.176 91.716  106.721 1.00 67.00  ? 403 TYR A CZ  1 
ATOM 2080 O OH  . TYR A 1 329 ? 127.478 90.706  106.099 1.00 64.05  ? 403 TYR A OH  1 
ATOM 2081 N N   . PRO A 1 330 ? 131.466 95.886  112.014 1.00 55.84  ? 404 PRO A N   1 
ATOM 2082 C CA  . PRO A 1 330 ? 132.161 96.997  112.669 1.00 52.16  ? 404 PRO A CA  1 
ATOM 2083 C C   . PRO A 1 330 ? 133.550 97.221  112.093 1.00 59.62  ? 404 PRO A C   1 
ATOM 2084 O O   . PRO A 1 330 ? 134.086 96.408  111.338 1.00 62.96  ? 404 PRO A O   1 
ATOM 2085 C CB  . PRO A 1 330 ? 132.233 96.550  114.131 1.00 49.93  ? 404 PRO A CB  1 
ATOM 2086 C CG  . PRO A 1 330 ? 132.245 95.066  114.053 1.00 48.59  ? 404 PRO A CG  1 
ATOM 2087 C CD  . PRO A 1 330 ? 131.378 94.700  112.882 1.00 49.81  ? 404 PRO A CD  1 
ATOM 2088 N N   . LEU A 1 331 ? 134.134 98.361  112.469 1.00 60.67  ? 405 LEU A N   1 
ATOM 2089 C CA  . LEU A 1 331 ? 135.477 98.722  112.042 1.00 52.57  ? 405 LEU A CA  1 
ATOM 2090 C C   . LEU A 1 331 ? 136.432 98.575  113.215 1.00 61.02  ? 405 LEU A C   1 
ATOM 2091 O O   . LEU A 1 331 ? 136.385 99.395  114.144 1.00 67.98  ? 405 LEU A O   1 
ATOM 2092 C CB  . LEU A 1 331 ? 135.504 100.153 111.510 1.00 52.78  ? 405 LEU A CB  1 
ATOM 2093 C CG  . LEU A 1 331 ? 136.817 100.663 110.916 1.00 58.63  ? 405 LEU A CG  1 
ATOM 2094 C CD1 . LEU A 1 331 ? 136.542 101.493 109.676 1.00 59.86  ? 405 LEU A CD1 1 
ATOM 2095 C CD2 . LEU A 1 331 ? 137.590 101.483 111.932 1.00 59.56  ? 405 LEU A CD2 1 
ATOM 2096 N N   . PRO A 1 332 ? 137.302 97.564  113.230 1.00 56.26  ? 406 PRO A N   1 
ATOM 2097 C CA  . PRO A 1 332 ? 138.241 97.417  114.350 1.00 53.22  ? 406 PRO A CA  1 
ATOM 2098 C C   . PRO A 1 332 ? 139.453 98.320  114.172 1.00 56.44  ? 406 PRO A C   1 
ATOM 2099 O O   . PRO A 1 332 ? 140.144 98.264  113.153 1.00 58.44  ? 406 PRO A O   1 
ATOM 2100 C CB  . PRO A 1 332 ? 138.629 95.936  114.294 1.00 52.32  ? 406 PRO A CB  1 
ATOM 2101 C CG  . PRO A 1 332 ? 138.450 95.559  112.873 1.00 49.15  ? 406 PRO A CG  1 
ATOM 2102 C CD  . PRO A 1 332 ? 137.338 96.408  112.319 1.00 55.22  ? 406 PRO A CD  1 
ATOM 2103 N N   . SER A 1 333 ? 139.705 99.158  115.174 1.00 63.74  ? 407 SER A N   1 
ATOM 2104 C CA  . SER A 1 333 ? 140.858 100.047 115.196 1.00 65.16  ? 407 SER A CA  1 
ATOM 2105 C C   . SER A 1 333 ? 141.745 99.677  116.375 1.00 70.48  ? 407 SER A C   1 
ATOM 2106 O O   . SER A 1 333 ? 141.265 99.567  117.508 1.00 73.16  ? 407 SER A O   1 
ATOM 2107 C CB  . SER A 1 333 ? 140.431 101.512 115.293 1.00 69.22  ? 407 SER A CB  1 
ATOM 2108 O OG  . SER A 1 333 ? 141.557 102.371 115.283 1.00 66.34  ? 407 SER A OG  1 
ATOM 2109 N N   . ILE A 1 334 ? 143.031 99.489  116.106 1.00 72.91  ? 408 ILE A N   1 
ATOM 2110 C CA  . ILE A 1 334 ? 143.981 99.074  117.131 1.00 73.21  ? 408 ILE A CA  1 
ATOM 2111 C C   . ILE A 1 334 ? 144.377 100.281 117.968 1.00 74.44  ? 408 ILE A C   1 
ATOM 2112 O O   . ILE A 1 334 ? 144.553 101.388 117.447 1.00 79.76  ? 408 ILE A O   1 
ATOM 2113 C CB  . ILE A 1 334 ? 145.208 98.410  116.483 1.00 74.59  ? 408 ILE A CB  1 
ATOM 2114 C CG1 . ILE A 1 334 ? 144.768 97.251  115.591 1.00 77.01  ? 408 ILE A CG1 1 
ATOM 2115 C CG2 . ILE A 1 334 ? 146.172 97.914  117.541 1.00 76.20  ? 408 ILE A CG2 1 
ATOM 2116 C CD1 . ILE A 1 334 ? 145.912 96.521  114.936 1.00 75.58  ? 408 ILE A CD1 1 
ATOM 2117 N N   . CYS A 1 335 ? 144.516 100.074 119.274 1.00 75.80  ? 409 CYS A N   1 
ATOM 2118 C CA  . CYS A 1 335 ? 144.880 101.133 120.201 1.00 77.51  ? 409 CYS A CA  1 
ATOM 2119 C C   . CYS A 1 335 ? 146.295 100.927 120.725 1.00 78.37  ? 409 CYS A C   1 
ATOM 2120 O O   . CYS A 1 335 ? 146.745 99.797  120.928 1.00 81.20  ? 409 CYS A O   1 
ATOM 2121 C CB  . CYS A 1 335 ? 143.897 101.196 121.370 1.00 82.73  ? 409 CYS A CB  1 
ATOM 2122 S SG  . CYS A 1 335 ? 142.187 101.464 120.874 1.00 92.79  ? 409 CYS A SG  1 
ATOM 2123 N N   . VAL A 1 336 ? 146.995 102.042 120.941 1.00 82.62  ? 410 VAL A N   1 
ATOM 2124 C CA  . VAL A 1 336 ? 148.388 101.968 121.369 1.00 85.07  ? 410 VAL A CA  1 
ATOM 2125 C C   . VAL A 1 336 ? 148.492 101.458 122.803 1.00 89.42  ? 410 VAL A C   1 
ATOM 2126 O O   . VAL A 1 336 ? 149.355 100.628 123.115 1.00 91.54  ? 410 VAL A O   1 
ATOM 2127 C CB  . VAL A 1 336 ? 149.082 103.332 121.181 1.00 86.30  ? 410 VAL A CB  1 
ATOM 2128 C CG1 . VAL A 1 336 ? 148.452 104.408 122.054 1.00 87.02  ? 410 VAL A CG1 1 
ATOM 2129 C CG2 . VAL A 1 336 ? 150.571 103.214 121.469 1.00 86.90  ? 410 VAL A CG2 1 
ATOM 2130 N N   . ARG A 1 337 ? 147.624 101.933 123.698 1.00 89.36  ? 411 ARG A N   1 
ATOM 2131 C CA  . ARG A 1 337 ? 147.672 101.523 125.097 1.00 85.76  ? 411 ARG A CA  1 
ATOM 2132 C C   . ARG A 1 337 ? 146.428 100.750 125.513 1.00 87.41  ? 411 ARG A C   1 
ATOM 2133 O O   . ARG A 1 337 ? 146.542 99.595  125.936 1.00 91.11  ? 411 ARG A O   1 
ATOM 2134 C CB  . ARG A 1 337 ? 147.867 102.753 125.993 1.00 84.39  ? 411 ARG A CB  1 
ATOM 2135 C CG  . ARG A 1 337 ? 149.286 103.290 126.018 1.00 86.94  ? 411 ARG A CG  1 
ATOM 2136 C CD  . ARG A 1 337 ? 150.243 102.287 126.642 1.00 90.00  ? 411 ARG A CD  1 
ATOM 2137 N NE  . ARG A 1 337 ? 149.755 101.790 127.922 1.00 92.21  ? 411 ARG A NE  1 
ATOM 2138 C CZ  . ARG A 1 337 ? 149.967 102.386 129.088 1.00 92.35  ? 411 ARG A CZ  1 
ATOM 2139 N NH1 . ARG A 1 337 ? 150.660 103.509 129.174 1.00 90.90  ? 411 ARG A NH1 1 
ATOM 2140 N NH2 . ARG A 1 337 ? 149.471 101.840 130.195 1.00 91.84  ? 411 ARG A NH2 1 
ATOM 2141 N N   . ASP A 1 338 ? 145.247 101.341 125.389 1.00 88.14  ? 412 ASP A N   1 
ATOM 2142 C CA  . ASP A 1 338 ? 143.991 100.697 125.748 1.00 88.75  ? 412 ASP A CA  1 
ATOM 2143 C C   . ASP A 1 338 ? 142.849 101.566 125.229 1.00 88.87  ? 412 ASP A C   1 
ATOM 2144 O O   . ASP A 1 338 ? 143.057 102.745 124.932 1.00 89.26  ? 412 ASP A O   1 
ATOM 2145 C CB  . ASP A 1 338 ? 143.869 100.497 127.270 1.00 90.76  ? 412 ASP A CB  1 
ATOM 2146 C CG  . ASP A 1 338 ? 144.227 101.738 128.058 1.00 95.06  ? 412 ASP A CG  1 
ATOM 2147 O OD1 . ASP A 1 338 ? 145.308 102.311 127.818 1.00 98.20  ? 412 ASP A OD1 1 
ATOM 2148 O OD2 . ASP A 1 338 ? 143.422 102.144 128.923 1.00 92.37  ? 412 ASP A OD2 1 
ATOM 2149 N N   . PRO A 1 339 ? 141.645 101.001 125.100 1.00 84.77  ? 413 PRO A N   1 
ATOM 2150 C CA  . PRO A 1 339 ? 140.522 101.797 124.578 1.00 85.12  ? 413 PRO A CA  1 
ATOM 2151 C C   . PRO A 1 339 ? 140.208 103.038 125.394 1.00 84.65  ? 413 PRO A C   1 
ATOM 2152 O O   . PRO A 1 339 ? 139.810 104.058 124.818 1.00 82.50  ? 413 PRO A O   1 
ATOM 2153 C CB  . PRO A 1 339 ? 139.350 100.803 124.598 1.00 84.53  ? 413 PRO A CB  1 
ATOM 2154 C CG  . PRO A 1 339 ? 139.812 99.648  125.430 1.00 84.45  ? 413 PRO A CG  1 
ATOM 2155 C CD  . PRO A 1 339 ? 141.283 99.582  125.227 1.00 85.43  ? 413 PRO A CD  1 
ATOM 2156 N N   . VAL A 1 340 ? 140.372 102.989 126.714 1.00 91.33  ? 414 VAL A N   1 
ATOM 2157 C CA  . VAL A 1 340 ? 139.932 104.098 127.554 1.00 94.02  ? 414 VAL A CA  1 
ATOM 2158 C C   . VAL A 1 340 ? 140.957 105.226 127.553 1.00 96.25  ? 414 VAL A C   1 
ATOM 2159 O O   . VAL A 1 340 ? 140.624 106.382 127.268 1.00 94.87  ? 414 VAL A O   1 
ATOM 2160 C CB  . VAL A 1 340 ? 139.642 103.602 128.981 1.00 91.84  ? 414 VAL A CB  1 
ATOM 2161 C CG1 . VAL A 1 340 ? 139.197 104.757 129.860 1.00 89.58  ? 414 VAL A CG1 1 
ATOM 2162 C CG2 . VAL A 1 340 ? 138.586 102.512 128.954 1.00 90.89  ? 414 VAL A CG2 1 
ATOM 2163 N N   . SER A 1 341 ? 142.216 104.912 127.866 1.00 96.08  ? 415 SER A N   1 
ATOM 2164 C CA  . SER A 1 341 ? 143.217 105.961 128.042 1.00 93.34  ? 415 SER A CA  1 
ATOM 2165 C C   . SER A 1 341 ? 143.471 106.715 126.744 1.00 91.10  ? 415 SER A C   1 
ATOM 2166 O O   . SER A 1 341 ? 143.648 107.938 126.753 1.00 92.78  ? 415 SER A O   1 
ATOM 2167 C CB  . SER A 1 341 ? 144.520 105.366 128.573 1.00 95.60  ? 415 SER A CB  1 
ATOM 2168 O OG  . SER A 1 341 ? 145.137 104.545 127.598 1.00 99.35  ? 415 SER A OG  1 
ATOM 2169 N N   . ASP A 1 342 ? 143.501 106.001 125.616 1.00 88.21  ? 416 ASP A N   1 
ATOM 2170 C CA  . ASP A 1 342 ? 143.781 106.651 124.341 1.00 92.93  ? 416 ASP A CA  1 
ATOM 2171 C C   . ASP A 1 342 ? 142.684 107.639 123.966 1.00 92.12  ? 416 ASP A C   1 
ATOM 2172 O O   . ASP A 1 342 ? 142.968 108.716 123.428 1.00 90.71  ? 416 ASP A O   1 
ATOM 2173 C CB  . ASP A 1 342 ? 143.961 105.602 123.245 1.00 91.81  ? 416 ASP A CB  1 
ATOM 2174 C CG  . ASP A 1 342 ? 145.098 104.647 123.540 1.00 94.12  ? 416 ASP A CG  1 
ATOM 2175 O OD1 . ASP A 1 342 ? 145.799 104.851 124.553 1.00 95.67  ? 416 ASP A OD1 1 
ATOM 2176 O OD2 . ASP A 1 342 ? 145.296 103.695 122.757 1.00 95.15  ? 416 ASP A OD2 1 
ATOM 2177 N N   . TRP A 1 343 ? 141.424 107.289 124.233 1.00 80.69  ? 417 TRP A N   1 
ATOM 2178 C CA  . TRP A 1 343 ? 140.326 108.190 123.901 1.00 77.43  ? 417 TRP A CA  1 
ATOM 2179 C C   . TRP A 1 343 ? 140.393 109.476 124.713 1.00 78.02  ? 417 TRP A C   1 
ATOM 2180 O O   . TRP A 1 343 ? 140.175 110.568 124.177 1.00 80.10  ? 417 TRP A O   1 
ATOM 2181 C CB  . TRP A 1 343 ? 138.985 107.489 124.109 1.00 75.26  ? 417 TRP A CB  1 
ATOM 2182 C CG  . TRP A 1 343 ? 137.822 108.317 123.678 1.00 75.87  ? 417 TRP A CG  1 
ATOM 2183 C CD1 . TRP A 1 343 ? 137.463 108.616 122.400 1.00 75.68  ? 417 TRP A CD1 1 
ATOM 2184 C CD2 . TRP A 1 343 ? 136.846 108.933 124.524 1.00 77.24  ? 417 TRP A CD2 1 
ATOM 2185 N NE1 . TRP A 1 343 ? 136.334 109.395 122.396 1.00 75.23  ? 417 TRP A NE1 1 
ATOM 2186 C CE2 . TRP A 1 343 ? 135.933 109.600 123.689 1.00 75.88  ? 417 TRP A CE2 1 
ATOM 2187 C CE3 . TRP A 1 343 ? 136.658 108.987 125.907 1.00 76.56  ? 417 TRP A CE3 1 
ATOM 2188 C CZ2 . TRP A 1 343 ? 134.851 110.315 124.189 1.00 73.78  ? 417 TRP A CZ2 1 
ATOM 2189 C CZ3 . TRP A 1 343 ? 135.583 109.695 126.401 1.00 73.06  ? 417 TRP A CZ3 1 
ATOM 2190 C CH2 . TRP A 1 343 ? 134.693 110.350 125.545 1.00 70.76  ? 417 TRP A CH2 1 
ATOM 2191 N N   . PHE A 1 344 ? 140.690 109.370 126.009 1.00 89.29  ? 418 PHE A N   1 
ATOM 2192 C CA  . PHE A 1 344 ? 140.788 110.570 126.833 1.00 89.36  ? 418 PHE A CA  1 
ATOM 2193 C C   . PHE A 1 344 ? 142.035 111.374 126.491 1.00 90.19  ? 418 PHE A C   1 
ATOM 2194 O O   . PHE A 1 344 ? 142.017 112.609 126.543 1.00 90.46  ? 418 PHE A O   1 
ATOM 2195 C CB  . PHE A 1 344 ? 140.764 110.192 128.312 1.00 88.49  ? 418 PHE A CB  1 
ATOM 2196 C CG  . PHE A 1 344 ? 139.405 109.790 128.805 1.00 90.14  ? 418 PHE A CG  1 
ATOM 2197 C CD1 . PHE A 1 344 ? 138.513 110.742 129.260 1.00 90.29  ? 418 PHE A CD1 1 
ATOM 2198 C CD2 . PHE A 1 344 ? 139.012 108.465 128.795 1.00 90.97  ? 418 PHE A CD2 1 
ATOM 2199 C CE1 . PHE A 1 344 ? 137.260 110.380 129.707 1.00 90.75  ? 418 PHE A CE1 1 
ATOM 2200 C CE2 . PHE A 1 344 ? 137.760 108.098 129.238 1.00 91.08  ? 418 PHE A CE2 1 
ATOM 2201 C CZ  . PHE A 1 344 ? 136.883 109.056 129.696 1.00 89.99  ? 418 PHE A CZ  1 
ATOM 2202 N N   . GLU A 1 345 ? 143.128 110.692 126.142 1.00 88.60  ? 419 GLU A N   1 
ATOM 2203 C CA  . GLU A 1 345 ? 144.317 111.398 125.675 1.00 82.91  ? 419 GLU A CA  1 
ATOM 2204 C C   . GLU A 1 345 ? 144.044 112.111 124.358 1.00 83.49  ? 419 GLU A C   1 
ATOM 2205 O O   . GLU A 1 345 ? 144.549 113.215 124.125 1.00 87.26  ? 419 GLU A O   1 
ATOM 2206 C CB  . GLU A 1 345 ? 145.483 110.422 125.527 1.00 83.20  ? 419 GLU A CB  1 
ATOM 2207 C CG  . GLU A 1 345 ? 146.748 111.049 124.968 1.00 88.26  ? 419 GLU A CG  1 
ATOM 2208 C CD  . GLU A 1 345 ? 147.830 110.026 124.684 1.00 89.87  ? 419 GLU A CD  1 
ATOM 2209 O OE1 . GLU A 1 345 ? 147.593 108.824 124.929 1.00 88.32  ? 419 GLU A OE1 1 
ATOM 2210 O OE2 . GLU A 1 345 ? 148.917 110.424 124.215 1.00 91.47  ? 419 GLU A OE2 1 
ATOM 2211 N N   . SER A 1 346 ? 143.247 111.493 123.485 1.00 85.76  ? 420 SER A N   1 
ATOM 2212 C CA  . SER A 1 346 ? 142.897 112.129 122.221 1.00 88.23  ? 420 SER A CA  1 
ATOM 2213 C C   . SER A 1 346 ? 142.062 113.384 122.443 1.00 91.45  ? 420 SER A C   1 
ATOM 2214 O O   . SER A 1 346 ? 142.231 114.381 121.732 1.00 94.20  ? 420 SER A O   1 
ATOM 2215 C CB  . SER A 1 346 ? 142.150 111.143 121.328 1.00 90.92  ? 420 SER A CB  1 
ATOM 2216 O OG  . SER A 1 346 ? 141.947 111.692 120.039 1.00 95.22  ? 420 SER A OG  1 
ATOM 2217 N N   . LEU A 1 347 ? 141.150 113.350 123.417 1.00 85.91  ? 421 LEU A N   1 
ATOM 2218 C CA  . LEU A 1 347 ? 140.280 114.497 123.659 1.00 83.95  ? 421 LEU A CA  1 
ATOM 2219 C C   . LEU A 1 347 ? 141.078 115.723 124.082 1.00 84.75  ? 421 LEU A C   1 
ATOM 2220 O O   . LEU A 1 347 ? 140.820 116.835 123.607 1.00 86.66  ? 421 LEU A O   1 
ATOM 2221 C CB  . LEU A 1 347 ? 139.240 114.150 124.721 1.00 84.09  ? 421 LEU A CB  1 
ATOM 2222 C CG  . LEU A 1 347 ? 138.150 113.154 124.334 1.00 82.87  ? 421 LEU A CG  1 
ATOM 2223 C CD1 . LEU A 1 347 ? 137.401 112.692 125.570 1.00 83.77  ? 421 LEU A CD1 1 
ATOM 2224 C CD2 . LEU A 1 347 ? 137.200 113.764 123.329 1.00 85.32  ? 421 LEU A CD2 1 
ATOM 2225 N N   . ALA A 1 348 ? 142.050 115.542 124.977 1.00 90.94  ? 422 ALA A N   1 
ATOM 2226 C CA  . ALA A 1 348 ? 142.816 116.681 125.471 1.00 92.68  ? 422 ALA A CA  1 
ATOM 2227 C C   . ALA A 1 348 ? 143.784 117.202 124.418 1.00 93.95  ? 422 ALA A C   1 
ATOM 2228 O O   . ALA A 1 348 ? 143.917 118.418 124.237 1.00 94.87  ? 422 ALA A O   1 
ATOM 2229 C CB  . ALA A 1 348 ? 143.566 116.294 126.744 1.00 92.00  ? 422 ALA A CB  1 
ATOM 2230 N N   . GLN A 1 349 ? 144.467 116.300 123.712 1.00 102.03 ? 423 GLN A N   1 
ATOM 2231 C CA  . GLN A 1 349 ? 145.504 116.720 122.777 1.00 103.07 ? 423 GLN A CA  1 
ATOM 2232 C C   . GLN A 1 349 ? 144.930 117.324 121.503 1.00 103.46 ? 423 GLN A C   1 
ATOM 2233 O O   . GLN A 1 349 ? 145.544 118.225 120.921 1.00 103.53 ? 423 GLN A O   1 
ATOM 2234 C CB  . GLN A 1 349 ? 146.410 115.535 122.437 1.00 103.37 ? 423 GLN A CB  1 
ATOM 2235 C CG  . GLN A 1 349 ? 147.661 115.908 121.659 1.00 104.36 ? 423 GLN A CG  1 
ATOM 2236 C CD  . GLN A 1 349 ? 148.642 114.759 121.549 1.00 104.41 ? 423 GLN A CD  1 
ATOM 2237 O OE1 . GLN A 1 349 ? 148.404 113.671 122.074 1.00 103.93 ? 423 GLN A OE1 1 
ATOM 2238 N NE2 . GLN A 1 349 ? 149.755 114.994 120.862 1.00 103.19 ? 423 GLN A NE2 1 
ATOM 2239 N N   . CYS A 1 350 ? 143.765 116.858 121.057 1.00 103.83 ? 424 CYS A N   1 
ATOM 2240 C CA  . CYS A 1 350 ? 143.179 117.324 119.806 1.00 105.23 ? 424 CYS A CA  1 
ATOM 2241 C C   . CYS A 1 350 ? 142.089 118.370 120.009 1.00 105.36 ? 424 CYS A C   1 
ATOM 2242 O O   . CYS A 1 350 ? 142.188 119.478 119.474 1.00 104.95 ? 424 CYS A O   1 
ATOM 2243 C CB  . CYS A 1 350 ? 142.616 116.136 119.016 1.00 103.13 ? 424 CYS A CB  1 
ATOM 2244 S SG  . CYS A 1 350 ? 141.653 116.603 117.560 1.00 103.21 ? 424 CYS A SG  1 
ATOM 2245 N N   . LEU A 1 351 ? 141.047 118.042 120.770 1.00 103.09 ? 425 LEU A N   1 
ATOM 2246 C CA  . LEU A 1 351 ? 139.877 118.900 120.900 1.00 101.07 ? 425 LEU A CA  1 
ATOM 2247 C C   . LEU A 1 351 ? 139.894 119.761 122.158 1.00 101.67 ? 425 LEU A C   1 
ATOM 2248 O O   . LEU A 1 351 ? 138.959 120.540 122.367 1.00 102.35 ? 425 LEU A O   1 
ATOM 2249 C CB  . LEU A 1 351 ? 138.603 118.049 120.868 1.00 101.43 ? 425 LEU A CB  1 
ATOM 2250 C CG  . LEU A 1 351 ? 137.322 118.719 120.372 1.00 102.83 ? 425 LEU A CG  1 
ATOM 2251 C CD1 . LEU A 1 351 ? 137.538 119.332 119.000 1.00 100.54 ? 425 LEU A CD1 1 
ATOM 2252 C CD2 . LEU A 1 351 ? 136.182 117.715 120.336 1.00 101.44 ? 425 LEU A CD2 1 
ATOM 2253 N N   . HIS A 1 352 ? 140.930 119.646 122.992 1.00 106.69 ? 426 HIS A N   1 
ATOM 2254 C CA  . HIS A 1 352 ? 141.064 120.437 124.217 1.00 105.49 ? 426 HIS A CA  1 
ATOM 2255 C C   . HIS A 1 352 ? 139.861 120.226 125.141 1.00 105.33 ? 426 HIS A C   1 
ATOM 2256 O O   . HIS A 1 352 ? 139.082 121.140 125.418 1.00 106.75 ? 426 HIS A O   1 
ATOM 2257 C CB  . HIS A 1 352 ? 141.263 121.922 123.892 1.00 106.39 ? 426 HIS A CB  1 
ATOM 2258 C CG  . HIS A 1 352 ? 142.409 122.191 122.967 1.00 106.98 ? 426 HIS A CG  1 
ATOM 2259 N ND1 . HIS A 1 352 ? 142.537 123.371 122.265 1.00 107.22 ? 426 HIS A ND1 1 
ATOM 2260 C CD2 . HIS A 1 352 ? 143.481 121.435 122.630 1.00 105.85 ? 426 HIS A CD2 1 
ATOM 2261 C CE1 . HIS A 1 352 ? 143.637 123.329 121.534 1.00 105.41 ? 426 HIS A CE1 1 
ATOM 2262 N NE2 . HIS A 1 352 ? 144.228 122.165 121.738 1.00 104.43 ? 426 HIS A NE2 1 
ATOM 2263 N N   . TRP A 1 353 ? 139.724 118.985 125.611 1.00 103.09 ? 427 TRP A N   1 
ATOM 2264 C CA  . TRP A 1 353 ? 138.564 118.612 126.415 1.00 104.63 ? 427 TRP A CA  1 
ATOM 2265 C C   . TRP A 1 353 ? 138.562 119.328 127.761 1.00 104.17 ? 427 TRP A C   1 
ATOM 2266 O O   . TRP A 1 353 ? 137.500 119.677 128.286 1.00 103.02 ? 427 TRP A O   1 
ATOM 2267 C CB  . TRP A 1 353 ? 138.533 117.099 126.620 1.00 105.69 ? 427 TRP A CB  1 
ATOM 2268 C CG  . TRP A 1 353 ? 137.488 116.642 127.593 1.00 105.69 ? 427 TRP A CG  1 
ATOM 2269 C CD1 . TRP A 1 353 ? 136.209 117.103 127.700 1.00 103.79 ? 427 TRP A CD1 1 
ATOM 2270 C CD2 . TRP A 1 353 ? 137.643 115.653 128.615 1.00 103.73 ? 427 TRP A CD2 1 
ATOM 2271 N NE1 . TRP A 1 353 ? 135.553 116.451 128.713 1.00 102.14 ? 427 TRP A NE1 1 
ATOM 2272 C CE2 . TRP A 1 353 ? 136.413 115.557 129.293 1.00 102.37 ? 427 TRP A CE2 1 
ATOM 2273 C CE3 . TRP A 1 353 ? 138.701 114.834 129.019 1.00 102.75 ? 427 TRP A CE3 1 
ATOM 2274 C CZ2 . TRP A 1 353 ? 136.211 114.677 130.352 1.00 102.84 ? 427 TRP A CZ2 1 
ATOM 2275 C CZ3 . TRP A 1 353 ? 138.499 113.962 130.071 1.00 103.51 ? 427 TRP A CZ3 1 
ATOM 2276 C CH2 . TRP A 1 353 ? 137.263 113.888 130.723 1.00 102.91 ? 427 TRP A CH2 1 
ATOM 2277 N N   . ASN A 1 354 ? 139.738 119.530 128.352 1.00 113.01 ? 428 ASN A N   1 
ATOM 2278 C CA  . ASN A 1 354 ? 139.830 120.133 129.674 1.00 112.47 ? 428 ASN A CA  1 
ATOM 2279 C C   . ASN A 1 354 ? 140.742 121.350 129.729 1.00 112.51 ? 428 ASN A C   1 
ATOM 2280 O O   . ASN A 1 354 ? 140.837 121.982 130.787 1.00 113.55 ? 428 ASN A O   1 
ATOM 2281 C CB  . ASN A 1 354 ? 140.307 119.094 130.699 1.00 113.47 ? 428 ASN A CB  1 
ATOM 2282 C CG  . ASN A 1 354 ? 141.678 118.538 130.371 1.00 116.13 ? 428 ASN A CG  1 
ATOM 2283 O OD1 . ASN A 1 354 ? 142.697 119.066 130.817 1.00 115.77 ? 428 ASN A OD1 1 
ATOM 2284 N ND2 . ASN A 1 354 ? 141.711 117.467 129.588 1.00 114.62 ? 428 ASN A ND2 1 
ATOM 2285 N N   . VAL A 1 355 ? 141.410 121.699 128.635 1.00 109.43 ? 429 VAL A N   1 
ATOM 2286 C CA  . VAL A 1 355 ? 142.290 122.860 128.622 1.00 111.29 ? 429 VAL A CA  1 
ATOM 2287 C C   . VAL A 1 355 ? 141.691 123.967 127.763 1.00 110.44 ? 429 VAL A C   1 
ATOM 2288 O O   . VAL A 1 355 ? 140.822 124.714 128.213 1.00 109.66 ? 429 VAL A O   1 
ATOM 2289 C CB  . VAL A 1 355 ? 143.699 122.489 128.127 1.00 109.45 ? 429 VAL A CB  1 
ATOM 2290 C CG1 . VAL A 1 355 ? 144.295 121.392 128.997 1.00 106.97 ? 429 VAL A CG1 1 
ATOM 2291 C CG2 . VAL A 1 355 ? 143.653 122.057 126.671 1.00 105.72 ? 429 VAL A CG2 1 
ATOM 2292 N N   . SER B 1 21  ? 113.159 90.536  123.047 1.00 122.77 ? 95  SER B N   1 
ATOM 2293 C CA  . SER B 1 21  ? 112.222 91.522  123.573 1.00 124.02 ? 95  SER B CA  1 
ATOM 2294 C C   . SER B 1 21  ? 111.430 90.955  124.746 1.00 121.78 ? 95  SER B C   1 
ATOM 2295 O O   . SER B 1 21  ? 110.256 90.612  124.607 1.00 119.75 ? 95  SER B O   1 
ATOM 2296 C CB  . SER B 1 21  ? 111.269 91.995  122.474 1.00 125.22 ? 95  SER B CB  1 
ATOM 2297 O OG  . SER B 1 21  ? 110.517 90.914  121.951 1.00 126.73 ? 95  SER B OG  1 
ATOM 2298 N N   . VAL B 1 22  ? 112.084 90.856  125.904 1.00 116.18 ? 96  VAL B N   1 
ATOM 2299 C CA  . VAL B 1 22  ? 111.425 90.346  127.099 1.00 119.05 ? 96  VAL B CA  1 
ATOM 2300 C C   . VAL B 1 22  ? 110.394 91.359  127.577 1.00 120.51 ? 96  VAL B C   1 
ATOM 2301 O O   . VAL B 1 22  ? 110.659 92.568  127.618 1.00 120.07 ? 96  VAL B O   1 
ATOM 2302 C CB  . VAL B 1 22  ? 112.458 90.040  128.194 1.00 120.86 ? 96  VAL B CB  1 
ATOM 2303 C CG1 . VAL B 1 22  ? 111.778 89.449  129.421 1.00 120.20 ? 96  VAL B CG1 1 
ATOM 2304 C CG2 . VAL B 1 22  ? 113.527 89.096  127.664 1.00 118.63 ? 96  VAL B CG2 1 
ATOM 2305 N N   . ARG B 1 23  ? 109.205 90.871  127.932 1.00 119.14 ? 97  ARG B N   1 
ATOM 2306 C CA  . ARG B 1 23  ? 108.130 91.723  128.428 1.00 117.87 ? 97  ARG B CA  1 
ATOM 2307 C C   . ARG B 1 23  ? 107.932 91.575  129.933 1.00 116.82 ? 97  ARG B C   1 
ATOM 2308 O O   . ARG B 1 23  ? 108.017 92.561  130.671 1.00 117.22 ? 97  ARG B O   1 
ATOM 2309 C CB  . ARG B 1 23  ? 106.826 91.406  127.683 1.00 116.66 ? 97  ARG B CB  1 
ATOM 2310 C CG  . ARG B 1 23  ? 106.940 91.486  126.170 1.00 116.29 ? 97  ARG B CG  1 
ATOM 2311 C CD  . ARG B 1 23  ? 105.616 91.155  125.501 1.00 117.09 ? 97  ARG B CD  1 
ATOM 2312 N NE  . ARG B 1 23  ? 104.594 92.155  125.786 1.00 118.33 ? 97  ARG B NE  1 
ATOM 2313 C CZ  . ARG B 1 23  ? 104.359 93.222  125.035 1.00 117.32 ? 97  ARG B CZ  1 
ATOM 2314 N NH1 . ARG B 1 23  ? 105.056 93.462  123.937 1.00 114.98 ? 97  ARG B NH1 1 
ATOM 2315 N NH2 . ARG B 1 23  ? 103.398 94.069  125.395 1.00 117.63 ? 97  ARG B NH2 1 
ATOM 2316 N N   . LEU B 1 24  ? 107.685 90.354  130.403 1.00 117.49 ? 98  LEU B N   1 
ATOM 2317 C CA  . LEU B 1 24  ? 107.448 90.096  131.818 1.00 119.31 ? 98  LEU B CA  1 
ATOM 2318 C C   . LEU B 1 24  ? 107.420 88.592  132.045 1.00 119.42 ? 98  LEU B C   1 
ATOM 2319 O O   . LEU B 1 24  ? 107.100 87.822  131.135 1.00 119.13 ? 98  LEU B O   1 
ATOM 2320 C CB  . LEU B 1 24  ? 106.134 90.729  132.295 1.00 118.10 ? 98  LEU B CB  1 
ATOM 2321 C CG  . LEU B 1 24  ? 105.948 90.881  133.807 1.00 117.48 ? 98  LEU B CG  1 
ATOM 2322 C CD1 . LEU B 1 24  ? 107.111 91.649  134.418 1.00 116.53 ? 98  LEU B CD1 1 
ATOM 2323 C CD2 . LEU B 1 24  ? 104.626 91.565  134.119 1.00 116.14 ? 98  LEU B CD2 1 
ATOM 2324 N N   . THR B 1 25  ? 107.758 88.186  133.270 1.00 119.36 ? 99  THR B N   1 
ATOM 2325 C CA  . THR B 1 25  ? 107.726 86.778  133.670 1.00 118.80 ? 99  THR B CA  1 
ATOM 2326 C C   . THR B 1 25  ? 107.395 86.727  135.159 1.00 117.25 ? 99  THR B C   1 
ATOM 2327 O O   . THR B 1 25  ? 108.280 86.902  136.003 1.00 116.20 ? 99  THR B O   1 
ATOM 2328 C CB  . THR B 1 25  ? 109.049 86.080  133.372 1.00 118.77 ? 99  THR B CB  1 
ATOM 2329 O OG1 . THR B 1 25  ? 109.345 86.187  131.974 1.00 117.68 ? 99  THR B OG1 1 
ATOM 2330 C CG2 . THR B 1 25  ? 108.973 84.609  133.755 1.00 117.07 ? 99  THR B CG2 1 
ATOM 2331 N N   . TRP B 1 26  ? 106.120 86.491  135.476 1.00 108.17 ? 100 TRP B N   1 
ATOM 2332 C CA  . TRP B 1 26  ? 105.696 86.434  136.871 1.00 106.93 ? 100 TRP B CA  1 
ATOM 2333 C C   . TRP B 1 26  ? 106.092 85.128  137.548 1.00 106.35 ? 100 TRP B C   1 
ATOM 2334 O O   . TRP B 1 26  ? 106.349 85.123  138.757 1.00 105.53 ? 100 TRP B O   1 
ATOM 2335 C CB  . TRP B 1 26  ? 104.181 86.625  136.978 1.00 103.75 ? 100 TRP B CB  1 
ATOM 2336 C CG  . TRP B 1 26  ? 103.728 88.056  136.934 1.00 104.21 ? 100 TRP B CG  1 
ATOM 2337 C CD1 . TRP B 1 26  ? 102.746 88.575  136.144 1.00 103.81 ? 100 TRP B CD1 1 
ATOM 2338 C CD2 . TRP B 1 26  ? 104.223 89.146  137.725 1.00 105.54 ? 100 TRP B CD2 1 
ATOM 2339 N NE1 . TRP B 1 26  ? 102.604 89.919  136.384 1.00 102.32 ? 100 TRP B NE1 1 
ATOM 2340 C CE2 . TRP B 1 26  ? 103.498 90.294  137.351 1.00 105.02 ? 100 TRP B CE2 1 
ATOM 2341 C CE3 . TRP B 1 26  ? 105.209 89.264  138.710 1.00 106.02 ? 100 TRP B CE3 1 
ATOM 2342 C CZ2 . TRP B 1 26  ? 103.729 91.542  137.924 1.00 106.44 ? 100 TRP B CZ2 1 
ATOM 2343 C CZ3 . TRP B 1 26  ? 105.436 90.504  139.276 1.00 104.71 ? 100 TRP B CZ3 1 
ATOM 2344 C CH2 . TRP B 1 26  ? 104.700 91.626  138.883 1.00 104.10 ? 100 TRP B CH2 1 
ATOM 2345 N N   . ASN B 1 27  ? 106.118 84.022  136.799 1.00 111.51 ? 101 ASN B N   1 
ATOM 2346 C CA  . ASN B 1 27  ? 106.393 82.693  137.339 1.00 111.78 ? 101 ASN B CA  1 
ATOM 2347 C C   . ASN B 1 27  ? 105.312 82.301  138.340 1.00 111.55 ? 101 ASN B C   1 
ATOM 2348 O O   . ASN B 1 27  ? 104.504 81.406  138.073 1.00 112.19 ? 101 ASN B O   1 
ATOM 2349 C CB  . ASN B 1 27  ? 107.782 82.631  137.982 1.00 111.30 ? 101 ASN B CB  1 
ATOM 2350 C CG  . ASN B 1 27  ? 108.049 81.305  138.668 1.00 111.06 ? 101 ASN B CG  1 
ATOM 2351 O OD1 . ASN B 1 27  ? 108.283 81.253  139.875 1.00 111.21 ? 101 ASN B OD1 1 
ATOM 2352 N ND2 . ASN B 1 27  ? 108.016 80.224  137.897 1.00 110.57 ? 101 ASN B ND2 1 
ATOM 2353 N N   . LYS B 1 28  ? 105.290 82.965  139.492 1.00 106.21 ? 102 LYS B N   1 
ATOM 2354 C CA  . LYS B 1 28  ? 104.233 82.801  140.480 1.00 106.05 ? 102 LYS B CA  1 
ATOM 2355 C C   . LYS B 1 28  ? 103.331 84.028  140.425 1.00 105.99 ? 102 LYS B C   1 
ATOM 2356 O O   . LYS B 1 28  ? 103.824 85.159  140.349 1.00 105.28 ? 102 LYS B O   1 
ATOM 2357 C CB  . LYS B 1 28  ? 104.816 82.616  141.881 1.00 105.62 ? 102 LYS B CB  1 
ATOM 2358 C CG  . LYS B 1 28  ? 103.774 82.570  142.988 1.00 105.38 ? 102 LYS B CG  1 
ATOM 2359 C CD  . LYS B 1 28  ? 104.305 83.181  144.274 1.00 106.04 ? 102 LYS B CD  1 
ATOM 2360 C CE  . LYS B 1 28  ? 104.659 84.646  144.082 1.00 104.85 ? 102 LYS B CE  1 
ATOM 2361 N NZ  . LYS B 1 28  ? 105.165 85.265  145.338 1.00 104.84 ? 102 LYS B NZ  1 
ATOM 2362 N N   . SER B 1 29  ? 102.016 83.803  140.452 1.00 100.14 ? 103 SER B N   1 
ATOM 2363 C CA  . SER B 1 29  ? 101.040 84.882  140.357 1.00 97.93  ? 103 SER B CA  1 
ATOM 2364 C C   . SER B 1 29  ? 101.238 85.866  141.503 1.00 96.20  ? 103 SER B C   1 
ATOM 2365 O O   . SER B 1 29  ? 101.523 85.452  142.633 1.00 95.25  ? 103 SER B O   1 
ATOM 2366 C CB  . SER B 1 29  ? 99.616  84.324  140.372 1.00 95.61  ? 103 SER B CB  1 
ATOM 2367 O OG  . SER B 1 29  ? 99.403  83.438  139.287 1.00 95.82  ? 103 SER B OG  1 
ATOM 2368 N N   . PRO B 1 30  ? 101.109 87.169  141.252 1.00 90.54  ? 104 PRO B N   1 
ATOM 2369 C CA  . PRO B 1 30  ? 101.365 88.148  142.312 1.00 90.61  ? 104 PRO B CA  1 
ATOM 2370 C C   . PRO B 1 30  ? 100.355 88.030  143.444 1.00 95.70  ? 104 PRO B C   1 
ATOM 2371 O O   . PRO B 1 30  ? 99.161  87.815  143.226 1.00 96.14  ? 104 PRO B O   1 
ATOM 2372 C CB  . PRO B 1 30  ? 101.244 89.491  141.588 1.00 87.05  ? 104 PRO B CB  1 
ATOM 2373 C CG  . PRO B 1 30  ? 100.306 89.217  140.472 1.00 85.36  ? 104 PRO B CG  1 
ATOM 2374 C CD  . PRO B 1 30  ? 100.577 87.802  140.033 1.00 88.58  ? 104 PRO B CD  1 
ATOM 2375 N N   . LYS B 1 31  ? 100.857 88.173  144.669 1.00 98.52  ? 105 LYS B N   1 
ATOM 2376 C CA  . LYS B 1 31  ? 100.011 88.107  145.853 1.00 95.28  ? 105 LYS B CA  1 
ATOM 2377 C C   . LYS B 1 31  ? 100.326 89.255  146.801 1.00 94.29  ? 105 LYS B C   1 
ATOM 2378 O O   . LYS B 1 31  ? 99.502  89.613  147.648 1.00 92.07  ? 105 LYS B O   1 
ATOM 2379 C CB  . LYS B 1 31  ? 100.188 86.767  146.568 1.00 94.17  ? 105 LYS B CB  1 
ATOM 2380 C CG  . LYS B 1 31  ? 99.677  85.570  145.781 1.00 94.39  ? 105 LYS B CG  1 
ATOM 2381 C CD  . LYS B 1 31  ? 99.906  84.272  146.537 1.00 95.08  ? 105 LYS B CD  1 
ATOM 2382 C CE  . LYS B 1 31  ? 99.373  83.079  145.762 1.00 94.60  ? 105 LYS B CE  1 
ATOM 2383 N NZ  . LYS B 1 31  ? 99.613  81.797  146.480 1.00 95.06  ? 105 LYS B NZ  1 
ATOM 2384 N N   . SER B 1 32  ? 101.516 89.836  146.670 1.00 84.84  ? 106 SER B N   1 
ATOM 2385 C CA  . SER B 1 32  ? 101.966 90.922  147.529 1.00 80.99  ? 106 SER B CA  1 
ATOM 2386 C C   . SER B 1 32  ? 102.171 92.174  146.691 1.00 77.34  ? 106 SER B C   1 
ATOM 2387 O O   . SER B 1 32  ? 102.806 92.120  145.633 1.00 82.07  ? 106 SER B O   1 
ATOM 2388 C CB  . SER B 1 32  ? 103.263 90.550  148.254 1.00 85.25  ? 106 SER B CB  1 
ATOM 2389 O OG  . SER B 1 32  ? 103.819 91.674  148.914 1.00 86.30  ? 106 SER B OG  1 
ATOM 2390 N N   . VAL B 1 33  ? 101.630 93.293  147.162 1.00 62.39  ? 107 VAL B N   1 
ATOM 2391 C CA  . VAL B 1 33  ? 101.750 94.579  146.489 1.00 68.65  ? 107 VAL B CA  1 
ATOM 2392 C C   . VAL B 1 33  ? 102.159 95.625  147.513 1.00 69.94  ? 107 VAL B C   1 
ATOM 2393 O O   . VAL B 1 33  ? 101.533 95.739  148.573 1.00 74.44  ? 107 VAL B O   1 
ATOM 2394 C CB  . VAL B 1 33  ? 100.436 94.987  145.796 1.00 69.00  ? 107 VAL B CB  1 
ATOM 2395 C CG1 . VAL B 1 33  ? 100.521 96.417  145.300 1.00 70.99  ? 107 VAL B CG1 1 
ATOM 2396 C CG2 . VAL B 1 33  ? 100.141 94.055  144.641 1.00 70.81  ? 107 VAL B CG2 1 
ATOM 2397 N N   . LEU B 1 34  ? 103.204 96.384  147.200 1.00 56.24  ? 108 LEU B N   1 
ATOM 2398 C CA  . LEU B 1 34  ? 103.636 97.504  148.024 1.00 45.03  ? 108 LEU B CA  1 
ATOM 2399 C C   . LEU B 1 34  ? 103.196 98.798  147.354 1.00 50.60  ? 108 LEU B C   1 
ATOM 2400 O O   . LEU B 1 34  ? 103.718 99.161  146.296 1.00 59.28  ? 108 LEU B O   1 
ATOM 2401 C CB  . LEU B 1 34  ? 105.149 97.492  148.221 1.00 43.12  ? 108 LEU B CB  1 
ATOM 2402 C CG  . LEU B 1 34  ? 105.711 98.673  149.012 1.00 58.56  ? 108 LEU B CG  1 
ATOM 2403 C CD1 . LEU B 1 34  ? 105.125 98.704  150.415 1.00 59.76  ? 108 LEU B CD1 1 
ATOM 2404 C CD2 . LEU B 1 34  ? 107.227 98.611  149.062 1.00 60.63  ? 108 LEU B CD2 1 
ATOM 2405 N N   . VAL B 1 35  ? 102.241 99.489  147.969 1.00 51.09  ? 109 VAL B N   1 
ATOM 2406 C CA  . VAL B 1 35  ? 101.713 100.742 147.445 1.00 46.49  ? 109 VAL B CA  1 
ATOM 2407 C C   . VAL B 1 35  ? 102.339 101.878 148.235 1.00 52.42  ? 109 VAL B C   1 
ATOM 2408 O O   . VAL B 1 35  ? 102.144 101.980 149.453 1.00 66.55  ? 109 VAL B O   1 
ATOM 2409 C CB  . VAL B 1 35  ? 100.181 100.795 147.527 1.00 55.99  ? 109 VAL B CB  1 
ATOM 2410 C CG1 . VAL B 1 35  ? 99.669  102.098 146.939 1.00 60.09  ? 109 VAL B CG1 1 
ATOM 2411 C CG2 . VAL B 1 35  ? 99.574  99.605  146.808 1.00 58.14  ? 109 VAL B CG2 1 
ATOM 2412 N N   . ILE B 1 36  ? 103.090 102.731 147.546 1.00 51.11  ? 110 ILE B N   1 
ATOM 2413 C CA  . ILE B 1 36  ? 103.761 103.867 148.159 1.00 51.59  ? 110 ILE B CA  1 
ATOM 2414 C C   . ILE B 1 36  ? 103.243 105.141 147.509 1.00 55.71  ? 110 ILE B C   1 
ATOM 2415 O O   . ILE B 1 36  ? 103.159 105.238 146.279 1.00 62.29  ? 110 ILE B O   1 
ATOM 2416 C CB  . ILE B 1 36  ? 105.296 103.751 148.048 1.00 49.34  ? 110 ILE B CB  1 
ATOM 2417 C CG1 . ILE B 1 36  ? 105.752 103.709 146.593 1.00 49.48  ? 110 ILE B CG1 1 
ATOM 2418 C CG2 . ILE B 1 36  ? 105.786 102.501 148.754 1.00 57.01  ? 110 ILE B CG2 1 
ATOM 2419 C CD1 . ILE B 1 36  ? 107.250 103.796 146.439 1.00 51.09  ? 110 ILE B CD1 1 
ATOM 2420 N N   . LYS B 1 37  ? 102.867 106.106 148.339 1.00 75.84  ? 111 LYS B N   1 
ATOM 2421 C CA  . LYS B 1 37  ? 102.264 107.349 147.889 1.00 79.16  ? 111 LYS B CA  1 
ATOM 2422 C C   . LYS B 1 37  ? 103.248 108.494 148.080 1.00 86.99  ? 111 LYS B C   1 
ATOM 2423 O O   . LYS B 1 37  ? 104.047 108.495 149.021 1.00 89.69  ? 111 LYS B O   1 
ATOM 2424 C CB  . LYS B 1 37  ? 100.964 107.633 148.652 1.00 86.78  ? 111 LYS B CB  1 
ATOM 2425 C CG  . LYS B 1 37  ? 100.176 108.830 148.149 1.00 88.47  ? 111 LYS B CG  1 
ATOM 2426 C CD  . LYS B 1 37  ? 98.876  108.982 148.920 1.00 88.58  ? 111 LYS B CD  1 
ATOM 2427 C CE  . LYS B 1 37  ? 99.143  109.214 150.398 1.00 84.78  ? 111 LYS B CE  1 
ATOM 2428 N NZ  . LYS B 1 37  ? 97.883  109.330 151.179 1.00 86.66  ? 111 LYS B NZ  1 
ATOM 2429 N N   . LYS B 1 38  ? 103.186 109.470 147.171 1.00 100.33 ? 112 LYS B N   1 
ATOM 2430 C CA  . LYS B 1 38  ? 104.090 110.614 147.238 1.00 103.94 ? 112 LYS B CA  1 
ATOM 2431 C C   . LYS B 1 38  ? 103.891 111.433 148.507 1.00 102.82 ? 112 LYS B C   1 
ATOM 2432 O O   . LYS B 1 38  ? 104.815 112.142 148.921 1.00 101.97 ? 112 LYS B O   1 
ATOM 2433 C CB  . LYS B 1 38  ? 103.901 111.496 146.001 1.00 102.49 ? 112 LYS B CB  1 
ATOM 2434 C CG  . LYS B 1 38  ? 105.017 112.502 145.767 1.00 101.75 ? 112 LYS B CG  1 
ATOM 2435 C CD  . LYS B 1 38  ? 104.802 113.272 144.473 1.00 100.88 ? 112 LYS B CD  1 
ATOM 2436 C CE  . LYS B 1 38  ? 105.935 114.252 144.217 1.00 99.93  ? 112 LYS B CE  1 
ATOM 2437 N NZ  . LYS B 1 38  ? 105.752 114.993 142.939 1.00 98.79  ? 112 LYS B NZ  1 
ATOM 2438 N N   . MET B 1 39  ? 102.708 111.356 149.122 1.00 111.35 ? 113 MET B N   1 
ATOM 2439 C CA  . MET B 1 39  ? 102.402 112.018 150.388 1.00 112.57 ? 113 MET B CA  1 
ATOM 2440 C C   . MET B 1 39  ? 102.458 113.537 150.269 1.00 113.32 ? 113 MET B C   1 
ATOM 2441 O O   . MET B 1 39  ? 102.822 114.074 149.217 1.00 112.69 ? 113 MET B O   1 
ATOM 2442 C CB  . MET B 1 39  ? 103.351 111.539 151.492 1.00 111.05 ? 113 MET B CB  1 
ATOM 2443 C CG  . MET B 1 39  ? 103.208 110.067 151.840 1.00 110.72 ? 113 MET B CG  1 
ATOM 2444 S SD  . MET B 1 39  ? 104.427 109.521 153.052 1.00 118.93 ? 113 MET B SD  1 
ATOM 2445 C CE  . MET B 1 39  ? 104.091 110.650 154.401 1.00 111.25 ? 113 MET B CE  1 
ATOM 2446 N N   . ARG B 1 40  ? 102.084 114.233 151.347 1.00 113.48 ? 114 ARG B N   1 
ATOM 2447 C CA  . ARG B 1 40  ? 102.098 115.696 151.394 1.00 113.79 ? 114 ARG B CA  1 
ATOM 2448 C C   . ARG B 1 40  ? 101.257 116.300 150.271 1.00 112.66 ? 114 ARG B C   1 
ATOM 2449 O O   . ARG B 1 40  ? 101.613 117.326 149.687 1.00 112.91 ? 114 ARG B O   1 
ATOM 2450 C CB  . ARG B 1 40  ? 103.529 116.239 151.349 1.00 114.03 ? 114 ARG B CB  1 
ATOM 2451 C CG  . ARG B 1 40  ? 104.362 115.915 152.577 1.00 113.23 ? 114 ARG B CG  1 
ATOM 2452 C CD  . ARG B 1 40  ? 105.749 116.531 152.473 1.00 112.71 ? 114 ARG B CD  1 
ATOM 2453 N NE  . ARG B 1 40  ? 106.593 116.176 153.608 1.00 114.53 ? 114 ARG B NE  1 
ATOM 2454 C CZ  . ARG B 1 40  ? 107.878 116.483 153.712 1.00 115.74 ? 114 ARG B CZ  1 
ATOM 2455 N NH1 . ARG B 1 40  ? 108.507 117.156 152.763 1.00 115.57 ? 114 ARG B NH1 1 
ATOM 2456 N NH2 . ARG B 1 40  ? 108.549 116.106 154.796 1.00 114.03 ? 114 ARG B NH2 1 
ATOM 2457 N N   . ASP B 1 41  ? 100.131 115.661 149.964 1.00 102.50 ? 115 ASP B N   1 
ATOM 2458 C CA  . ASP B 1 41  ? 99.249  116.140 148.905 1.00 102.19 ? 115 ASP B CA  1 
ATOM 2459 C C   . ASP B 1 41  ? 97.837  115.655 149.188 1.00 105.12 ? 115 ASP B C   1 
ATOM 2460 O O   . ASP B 1 41  ? 97.594  114.446 149.231 1.00 105.95 ? 115 ASP B O   1 
ATOM 2461 C CB  . ASP B 1 41  ? 99.722  115.657 147.533 1.00 102.97 ? 115 ASP B CB  1 
ATOM 2462 C CG  . ASP B 1 41  ? 98.976  116.322 146.390 1.00 104.76 ? 115 ASP B CG  1 
ATOM 2463 O OD1 . ASP B 1 41  ? 98.186  117.253 146.650 1.00 103.46 ? 115 ASP B OD1 1 
ATOM 2464 O OD2 . ASP B 1 41  ? 99.183  115.914 145.228 1.00 103.93 ? 115 ASP B OD2 1 
ATOM 2465 N N   . ALA B 1 42  ? 96.914  116.599 149.378 1.00 104.02 ? 116 ALA B N   1 
ATOM 2466 C CA  . ALA B 1 42  ? 95.517  116.235 149.586 1.00 104.00 ? 116 ALA B CA  1 
ATOM 2467 C C   . ALA B 1 42  ? 94.918  115.616 148.331 1.00 102.38 ? 116 ALA B C   1 
ATOM 2468 O O   . ALA B 1 42  ? 94.073  114.717 148.417 1.00 100.93 ? 116 ALA B O   1 
ATOM 2469 C CB  . ALA B 1 42  ? 94.713  117.460 150.019 1.00 102.64 ? 116 ALA B CB  1 
ATOM 2470 N N   . SER B 1 43  ? 95.346  116.082 147.155 1.00 98.68  ? 117 SER B N   1 
ATOM 2471 C CA  . SER B 1 43  ? 94.809  115.570 145.901 1.00 99.85  ? 117 SER B CA  1 
ATOM 2472 C C   . SER B 1 43  ? 95.072  114.083 145.719 1.00 100.48 ? 117 SER B C   1 
ATOM 2473 O O   . SER B 1 43  ? 94.321  113.417 144.999 1.00 101.76 ? 117 SER B O   1 
ATOM 2474 C CB  . SER B 1 43  ? 95.396  116.348 144.723 1.00 100.56 ? 117 SER B CB  1 
ATOM 2475 O OG  . SER B 1 43  ? 94.898  115.861 143.489 1.00 98.95  ? 117 SER B OG  1 
ATOM 2476 N N   . LEU B 1 44  ? 96.119  113.548 146.345 1.00 98.51  ? 118 LEU B N   1 
ATOM 2477 C CA  . LEU B 1 44  ? 96.422  112.127 146.251 1.00 98.45  ? 118 LEU B CA  1 
ATOM 2478 C C   . LEU B 1 44  ? 95.761  111.302 147.344 1.00 100.22 ? 118 LEU B C   1 
ATOM 2479 O O   . LEU B 1 44  ? 95.871  110.071 147.319 1.00 103.31 ? 118 LEU B O   1 
ATOM 2480 C CB  . LEU B 1 44  ? 97.938  111.904 146.297 1.00 98.76  ? 118 LEU B CB  1 
ATOM 2481 C CG  . LEU B 1 44  ? 98.768  112.660 145.259 1.00 101.94 ? 118 LEU B CG  1 
ATOM 2482 C CD1 . LEU B 1 44  ? 100.248 112.348 145.423 1.00 99.96  ? 118 LEU B CD1 1 
ATOM 2483 C CD2 . LEU B 1 44  ? 98.299  112.328 143.851 1.00 99.06  ? 118 LEU B CD2 1 
ATOM 2484 N N   . LEU B 1 45  ? 95.086  111.941 148.302 1.00 103.03 ? 119 LEU B N   1 
ATOM 2485 C CA  . LEU B 1 45  ? 94.455  111.192 149.385 1.00 104.18 ? 119 LEU B CA  1 
ATOM 2486 C C   . LEU B 1 45  ? 93.288  110.358 148.874 1.00 104.40 ? 119 LEU B C   1 
ATOM 2487 O O   . LEU B 1 45  ? 93.196  109.159 149.162 1.00 103.19 ? 119 LEU B O   1 
ATOM 2488 C CB  . LEU B 1 45  ? 93.990  112.148 150.484 1.00 104.50 ? 119 LEU B CB  1 
ATOM 2489 C CG  . LEU B 1 45  ? 95.069  112.957 151.208 1.00 105.73 ? 119 LEU B CG  1 
ATOM 2490 C CD1 . LEU B 1 45  ? 94.440  113.883 152.237 1.00 103.21 ? 119 LEU B CD1 1 
ATOM 2491 C CD2 . LEU B 1 45  ? 96.085  112.037 151.863 1.00 105.30 ? 119 LEU B CD2 1 
ATOM 2492 N N   . GLN B 1 46  ? 92.383  110.977 148.115 1.00 106.05 ? 120 GLN B N   1 
ATOM 2493 C CA  . GLN B 1 46  ? 91.207  110.256 147.630 1.00 105.75 ? 120 GLN B CA  1 
ATOM 2494 C C   . GLN B 1 46  ? 91.554  109.122 146.672 1.00 104.54 ? 120 GLN B C   1 
ATOM 2495 O O   . GLN B 1 46  ? 91.041  108.006 146.867 1.00 102.03 ? 120 GLN B O   1 
ATOM 2496 C CB  . GLN B 1 46  ? 90.220  111.245 147.000 1.00 103.77 ? 120 GLN B CB  1 
ATOM 2497 C CG  . GLN B 1 46  ? 88.933  110.606 146.507 1.00 104.19 ? 120 GLN B CG  1 
ATOM 2498 C CD  . GLN B 1 46  ? 87.991  111.610 145.876 1.00 105.49 ? 120 GLN B CD  1 
ATOM 2499 O OE1 . GLN B 1 46  ? 88.320  112.789 145.745 1.00 104.08 ? 120 GLN B OE1 1 
ATOM 2500 N NE2 . GLN B 1 46  ? 86.812  111.147 145.479 1.00 106.03 ? 120 GLN B NE2 1 
ATOM 2501 N N   . PRO B 1 47  ? 92.384  109.313 145.638 1.00 104.45 ? 121 PRO B N   1 
ATOM 2502 C CA  . PRO B 1 47  ? 92.694  108.180 144.750 1.00 103.40 ? 121 PRO B CA  1 
ATOM 2503 C C   . PRO B 1 47  ? 93.395  107.036 145.454 1.00 100.65 ? 121 PRO B C   1 
ATOM 2504 O O   . PRO B 1 47  ? 93.322  105.894 144.985 1.00 101.61 ? 121 PRO B O   1 
ATOM 2505 C CB  . PRO B 1 47  ? 93.587  108.812 143.673 1.00 103.25 ? 121 PRO B CB  1 
ATOM 2506 C CG  . PRO B 1 47  ? 93.252  110.258 143.704 1.00 102.33 ? 121 PRO B CG  1 
ATOM 2507 C CD  . PRO B 1 47  ? 92.993  110.560 145.143 1.00 103.61 ? 121 PRO B CD  1 
ATOM 2508 N N   . PHE B 1 48  ? 94.081  107.309 146.565 1.00 92.38  ? 122 PHE B N   1 
ATOM 2509 C CA  . PHE B 1 48  ? 94.707  106.233 147.326 1.00 95.28  ? 122 PHE B CA  1 
ATOM 2510 C C   . PHE B 1 48  ? 93.661  105.277 147.882 1.00 96.71  ? 122 PHE B C   1 
ATOM 2511 O O   . PHE B 1 48  ? 93.878  104.060 147.916 1.00 97.05  ? 122 PHE B O   1 
ATOM 2512 C CB  . PHE B 1 48  ? 95.560  106.816 148.452 1.00 95.47  ? 122 PHE B CB  1 
ATOM 2513 C CG  . PHE B 1 48  ? 96.239  105.779 149.299 1.00 90.39  ? 122 PHE B CG  1 
ATOM 2514 C CD1 . PHE B 1 48  ? 97.386  105.148 148.857 1.00 90.57  ? 122 PHE B CD1 1 
ATOM 2515 C CD2 . PHE B 1 48  ? 95.733  105.441 150.542 1.00 93.46  ? 122 PHE B CD2 1 
ATOM 2516 C CE1 . PHE B 1 48  ? 98.013  104.198 149.632 1.00 88.99  ? 122 PHE B CE1 1 
ATOM 2517 C CE2 . PHE B 1 48  ? 96.357  104.490 151.323 1.00 95.96  ? 122 PHE B CE2 1 
ATOM 2518 C CZ  . PHE B 1 48  ? 97.500  103.869 150.867 1.00 92.54  ? 122 PHE B CZ  1 
ATOM 2519 N N   . LYS B 1 49  ? 92.523  105.811 148.331 1.00 102.23 ? 123 LYS B N   1 
ATOM 2520 C CA  . LYS B 1 49  ? 91.471  104.960 148.879 1.00 103.18 ? 123 LYS B CA  1 
ATOM 2521 C C   . LYS B 1 49  ? 90.894  104.031 147.819 1.00 102.10 ? 123 LYS B C   1 
ATOM 2522 O O   . LYS B 1 49  ? 90.663  102.845 148.084 1.00 100.69 ? 123 LYS B O   1 
ATOM 2523 C CB  . LYS B 1 49  ? 90.365  105.820 149.492 1.00 104.01 ? 123 LYS B CB  1 
ATOM 2524 C CG  . LYS B 1 49  ? 90.854  107.089 150.169 1.00 103.28 ? 123 LYS B CG  1 
ATOM 2525 C CD  . LYS B 1 49  ? 91.513  106.779 151.503 1.00 103.19 ? 123 LYS B CD  1 
ATOM 2526 C CE  . LYS B 1 49  ? 91.798  108.047 152.292 1.00 102.70 ? 123 LYS B CE  1 
ATOM 2527 N NZ  . LYS B 1 49  ? 92.754  108.942 151.589 1.00 102.87 ? 123 LYS B NZ  1 
ATOM 2528 N N   . GLU B 1 50  ? 90.648  104.550 146.614 1.00 100.66 ? 124 GLU B N   1 
ATOM 2529 C CA  . GLU B 1 50  ? 89.997  103.748 145.584 1.00 99.35  ? 124 GLU B CA  1 
ATOM 2530 C C   . GLU B 1 50  ? 90.863  102.567 145.166 1.00 98.87  ? 124 GLU B C   1 
ATOM 2531 O O   . GLU B 1 50  ? 90.365  101.443 145.030 1.00 97.10  ? 124 GLU B O   1 
ATOM 2532 C CB  . GLU B 1 50  ? 89.662  104.618 144.374 1.00 99.16  ? 124 GLU B CB  1 
ATOM 2533 C CG  . GLU B 1 50  ? 88.728  105.775 144.680 1.00 100.88 ? 124 GLU B CG  1 
ATOM 2534 C CD  . GLU B 1 50  ? 88.450  106.634 143.463 1.00 102.93 ? 124 GLU B CD  1 
ATOM 2535 O OE1 . GLU B 1 50  ? 89.019  106.347 142.390 1.00 101.96 ? 124 GLU B OE1 1 
ATOM 2536 O OE2 . GLU B 1 50  ? 87.663  107.597 143.580 1.00 102.64 ? 124 GLU B OE2 1 
ATOM 2537 N N   . LEU B 1 51  ? 92.159  102.801 144.955 1.00 99.96  ? 125 LEU B N   1 
ATOM 2538 C CA  . LEU B 1 51  ? 93.042  101.725 144.516 1.00 101.71 ? 125 LEU B CA  1 
ATOM 2539 C C   . LEU B 1 51  ? 93.182  100.648 145.583 1.00 99.68  ? 125 LEU B C   1 
ATOM 2540 O O   . LEU B 1 51  ? 93.141  99.452  145.273 1.00 100.52 ? 125 LEU B O   1 
ATOM 2541 C CB  . LEU B 1 51  ? 94.411  102.291 144.142 1.00 103.43 ? 125 LEU B CB  1 
ATOM 2542 C CG  . LEU B 1 51  ? 95.443  101.289 143.621 1.00 99.57  ? 125 LEU B CG  1 
ATOM 2543 C CD1 . LEU B 1 51  ? 94.932  100.588 142.373 1.00 97.68  ? 125 LEU B CD1 1 
ATOM 2544 C CD2 . LEU B 1 51  ? 96.767  101.980 143.347 1.00 95.91  ? 125 LEU B CD2 1 
ATOM 2545 N N   . CYS B 1 52  ? 93.347  101.050 146.845 1.00 93.69  ? 126 CYS B N   1 
ATOM 2546 C CA  . CYS B 1 52  ? 93.576  100.074 147.905 1.00 93.10  ? 126 CYS B CA  1 
ATOM 2547 C C   . CYS B 1 52  ? 92.369  99.165  148.094 1.00 99.62  ? 126 CYS B C   1 
ATOM 2548 O O   . CYS B 1 52  ? 92.522  97.958  148.315 1.00 101.40 ? 126 CYS B O   1 
ATOM 2549 C CB  . CYS B 1 52  ? 93.925  100.787 149.209 1.00 92.52  ? 126 CYS B CB  1 
ATOM 2550 S SG  . CYS B 1 52  ? 95.471  101.706 149.146 1.00 85.22  ? 126 CYS B SG  1 
ATOM 2551 N N   . THR B 1 53  ? 91.160  99.726  148.014 1.00 102.07 ? 127 THR B N   1 
ATOM 2552 C CA  . THR B 1 53  ? 89.961  98.901  148.121 1.00 97.79  ? 127 THR B CA  1 
ATOM 2553 C C   . THR B 1 53  ? 89.889  97.891  146.984 1.00 96.60  ? 127 THR B C   1 
ATOM 2554 O O   . THR B 1 53  ? 89.556  96.721  147.202 1.00 95.87  ? 127 THR B O   1 
ATOM 2555 C CB  . THR B 1 53  ? 88.711  99.781  148.130 1.00 96.44  ? 127 THR B CB  1 
ATOM 2556 O OG1 . THR B 1 53  ? 88.757  100.690 147.024 1.00 98.51  ? 127 THR B OG1 1 
ATOM 2557 C CG2 . THR B 1 53  ? 88.627  100.572 149.426 1.00 95.32  ? 127 THR B CG2 1 
ATOM 2558 N N   . HIS B 1 54  ? 90.200  98.326  145.763 1.00 103.83 ? 128 HIS B N   1 
ATOM 2559 C CA  . HIS B 1 54  ? 90.146  97.421  144.621 1.00 106.91 ? 128 HIS B CA  1 
ATOM 2560 C C   . HIS B 1 54  ? 91.243  96.366  144.690 1.00 108.01 ? 128 HIS B C   1 
ATOM 2561 O O   . HIS B 1 54  ? 90.998  95.191  144.395 1.00 108.51 ? 128 HIS B O   1 
ATOM 2562 C CB  . HIS B 1 54  ? 90.242  98.215  143.321 1.00 108.61 ? 128 HIS B CB  1 
ATOM 2563 C CG  . HIS B 1 54  ? 89.081  99.131  143.087 1.00 108.78 ? 128 HIS B CG  1 
ATOM 2564 N ND1 . HIS B 1 54  ? 89.139  100.485 143.335 1.00 106.62 ? 128 HIS B ND1 1 
ATOM 2565 C CD2 . HIS B 1 54  ? 87.830  98.885  142.630 1.00 107.61 ? 128 HIS B CD2 1 
ATOM 2566 C CE1 . HIS B 1 54  ? 87.974  101.035 143.040 1.00 105.48 ? 128 HIS B CE1 1 
ATOM 2567 N NE2 . HIS B 1 54  ? 87.163  100.086 142.610 1.00 105.35 ? 128 HIS B NE2 1 
ATOM 2568 N N   . LEU B 1 55  ? 92.461  96.765  145.065 1.00 103.11 ? 129 LEU B N   1 
ATOM 2569 C CA  . LEU B 1 55  ? 93.539  95.790  145.200 1.00 100.65 ? 129 LEU B CA  1 
ATOM 2570 C C   . LEU B 1 55  ? 93.225  94.777  146.290 1.00 97.77  ? 129 LEU B C   1 
ATOM 2571 O O   . LEU B 1 55  ? 93.483  93.579  146.129 1.00 99.44  ? 129 LEU B O   1 
ATOM 2572 C CB  . LEU B 1 55  ? 94.864  96.495  145.492 1.00 100.26 ? 129 LEU B CB  1 
ATOM 2573 C CG  . LEU B 1 55  ? 95.448  97.379  144.390 1.00 103.29 ? 129 LEU B CG  1 
ATOM 2574 C CD1 . LEU B 1 55  ? 96.707  98.074  144.881 1.00 100.59 ? 129 LEU B CD1 1 
ATOM 2575 C CD2 . LEU B 1 55  ? 95.734  96.561  143.140 1.00 101.69 ? 129 LEU B CD2 1 
ATOM 2576 N N   . MET B 1 56  ? 92.667  95.241  147.409 1.00 99.76  ? 130 MET B N   1 
ATOM 2577 C CA  . MET B 1 56  ? 92.285  94.330  148.479 1.00 103.29 ? 130 MET B CA  1 
ATOM 2578 C C   . MET B 1 56  ? 91.049  93.517  148.119 1.00 103.51 ? 130 MET B C   1 
ATOM 2579 O O   . MET B 1 56  ? 90.830  92.452  148.706 1.00 104.55 ? 130 MET B O   1 
ATOM 2580 C CB  . MET B 1 56  ? 92.051  95.114  149.772 1.00 103.94 ? 130 MET B CB  1 
ATOM 2581 C CG  . MET B 1 56  ? 91.871  94.251  151.008 1.00 103.67 ? 130 MET B CG  1 
ATOM 2582 S SD  . MET B 1 56  ? 93.408  93.463  151.519 1.00 108.90 ? 130 MET B SD  1 
ATOM 2583 C CE  . MET B 1 56  ? 94.338  94.881  152.093 1.00 100.79 ? 130 MET B CE  1 
ATOM 2584 N N   . GLU B 1 57  ? 90.246  93.990  147.162 1.00 102.74 ? 131 GLU B N   1 
ATOM 2585 C CA  . GLU B 1 57  ? 89.078  93.227  146.735 1.00 102.74 ? 131 GLU B CA  1 
ATOM 2586 C C   . GLU B 1 57  ? 89.488  91.880  146.157 1.00 103.48 ? 131 GLU B C   1 
ATOM 2587 O O   . GLU B 1 57  ? 88.865  90.853  146.452 1.00 105.09 ? 131 GLU B O   1 
ATOM 2588 C CB  . GLU B 1 57  ? 88.271  94.030  145.716 1.00 103.99 ? 131 GLU B CB  1 
ATOM 2589 C CG  . GLU B 1 57  ? 86.966  93.375  145.305 1.00 105.78 ? 131 GLU B CG  1 
ATOM 2590 C CD  . GLU B 1 57  ? 86.176  94.219  144.326 1.00 106.03 ? 131 GLU B CD  1 
ATOM 2591 O OE1 . GLU B 1 57  ? 86.552  95.391  144.110 1.00 104.25 ? 131 GLU B OE1 1 
ATOM 2592 O OE2 . GLU B 1 57  ? 85.178  93.712  143.772 1.00 105.48 ? 131 GLU B OE2 1 
ATOM 2593 N N   . GLU B 1 58  ? 90.530  91.862  145.334 1.00 105.86 ? 132 GLU B N   1 
ATOM 2594 C CA  . GLU B 1 58  ? 91.094  90.608  144.869 1.00 106.43 ? 132 GLU B CA  1 
ATOM 2595 C C   . GLU B 1 58  ? 91.903  89.954  145.986 1.00 109.68 ? 132 GLU B C   1 
ATOM 2596 O O   . GLU B 1 58  ? 92.401  90.615  146.902 1.00 111.97 ? 132 GLU B O   1 
ATOM 2597 C CB  . GLU B 1 58  ? 91.962  90.838  143.633 1.00 106.94 ? 132 GLU B CB  1 
ATOM 2598 C CG  . GLU B 1 58  ? 91.238  91.543  142.496 1.00 108.95 ? 132 GLU B CG  1 
ATOM 2599 C CD  . GLU B 1 58  ? 92.152  91.867  141.331 1.00 110.51 ? 132 GLU B CD  1 
ATOM 2600 O OE1 . GLU B 1 58  ? 93.348  91.513  141.393 1.00 111.68 ? 132 GLU B OE1 1 
ATOM 2601 O OE2 . GLU B 1 58  ? 91.674  92.479  140.352 1.00 109.03 ? 132 GLU B OE2 1 
ATOM 2602 N N   . ASN B 1 59  ? 92.034  88.629  145.905 1.00 115.68 ? 133 ASN B N   1 
ATOM 2603 C CA  . ASN B 1 59  ? 92.749  87.859  146.924 1.00 114.99 ? 133 ASN B CA  1 
ATOM 2604 C C   . ASN B 1 59  ? 94.253  88.102  146.776 1.00 115.35 ? 133 ASN B C   1 
ATOM 2605 O O   . ASN B 1 59  ? 95.022  87.262  146.306 1.00 116.38 ? 133 ASN B O   1 
ATOM 2606 C CB  . ASN B 1 59  ? 92.396  86.381  146.823 1.00 115.52 ? 133 ASN B CB  1 
ATOM 2607 C CG  . ASN B 1 59  ? 92.479  85.851  145.401 1.00 118.37 ? 133 ASN B CG  1 
ATOM 2608 O OD1 . ASN B 1 59  ? 93.029  86.501  144.512 1.00 118.70 ? 133 ASN B OD1 1 
ATOM 2609 N ND2 . ASN B 1 59  ? 91.931  84.662  145.183 1.00 117.42 ? 133 ASN B ND2 1 
ATOM 2610 N N   . MET B 1 60  ? 94.667  89.293  147.204 1.00 100.54 ? 134 MET B N   1 
ATOM 2611 C CA  . MET B 1 60  ? 96.040  89.744  147.031 1.00 100.09 ? 134 MET B CA  1 
ATOM 2612 C C   . MET B 1 60  ? 96.436  90.603  148.221 1.00 97.81  ? 134 MET B C   1 
ATOM 2613 O O   . MET B 1 60  ? 95.807  91.632  148.482 1.00 95.82  ? 134 MET B O   1 
ATOM 2614 C CB  . MET B 1 60  ? 96.186  90.528  145.722 1.00 97.48  ? 134 MET B CB  1 
ATOM 2615 C CG  . MET B 1 60  ? 97.601  90.926  145.364 1.00 93.13  ? 134 MET B CG  1 
ATOM 2616 S SD  . MET B 1 60  ? 97.641  91.782  143.780 1.00 100.30 ? 134 MET B SD  1 
ATOM 2617 C CE  . MET B 1 60  ? 97.321  90.426  142.657 1.00 97.43  ? 134 MET B CE  1 
ATOM 2618 N N   . ILE B 1 61  ? 97.476  90.174  148.940 1.00 90.05  ? 135 ILE B N   1 
ATOM 2619 C CA  . ILE B 1 61  ? 97.925  90.894  150.126 1.00 87.63  ? 135 ILE B CA  1 
ATOM 2620 C C   . ILE B 1 61  ? 98.505  92.241  149.721 1.00 85.79  ? 135 ILE B C   1 
ATOM 2621 O O   . ILE B 1 61  ? 99.229  92.355  148.722 1.00 90.53  ? 135 ILE B O   1 
ATOM 2622 C CB  . ILE B 1 61  ? 98.952  90.054  150.903 1.00 88.29  ? 135 ILE B CB  1 
ATOM 2623 C CG1 . ILE B 1 61  ? 98.392  88.658  151.183 1.00 88.99  ? 135 ILE B CG1 1 
ATOM 2624 C CG2 . ILE B 1 61  ? 99.338  90.743  152.204 1.00 85.61  ? 135 ILE B CG2 1 
ATOM 2625 C CD1 . ILE B 1 61  ? 97.142  88.661  152.036 1.00 85.12  ? 135 ILE B CD1 1 
ATOM 2626 N N   . VAL B 1 62  ? 98.187  93.274  150.496 1.00 64.33  ? 136 VAL B N   1 
ATOM 2627 C CA  . VAL B 1 62  ? 98.615  94.639  150.217 1.00 62.86  ? 136 VAL B CA  1 
ATOM 2628 C C   . VAL B 1 62  ? 99.535  95.102  151.336 1.00 66.97  ? 136 VAL B C   1 
ATOM 2629 O O   . VAL B 1 62  ? 99.183  95.011  152.518 1.00 74.09  ? 136 VAL B O   1 
ATOM 2630 C CB  . VAL B 1 62  ? 97.412  95.586  150.073 1.00 67.45  ? 136 VAL B CB  1 
ATOM 2631 C CG1 . VAL B 1 62  ? 97.885  97.007  149.821 1.00 71.07  ? 136 VAL B CG1 1 
ATOM 2632 C CG2 . VAL B 1 62  ? 96.500  95.114  148.954 1.00 70.19  ? 136 VAL B CG2 1 
ATOM 2633 N N   . TYR B 1 63  ? 100.709 95.598  150.963 1.00 66.29  ? 137 TYR B N   1 
ATOM 2634 C CA  . TYR B 1 63  ? 101.642 96.210  151.896 1.00 54.81  ? 137 TYR B CA  1 
ATOM 2635 C C   . TYR B 1 63  ? 101.576 97.723  151.764 1.00 56.69  ? 137 TYR B C   1 
ATOM 2636 O O   . TYR B 1 63  ? 101.455 98.257  150.658 1.00 76.05  ? 137 TYR B O   1 
ATOM 2637 C CB  . TYR B 1 63  ? 103.073 95.739  151.636 1.00 66.04  ? 137 TYR B CB  1 
ATOM 2638 C CG  . TYR B 1 63  ? 103.435 94.421  152.275 1.00 66.63  ? 137 TYR B CG  1 
ATOM 2639 C CD1 . TYR B 1 63  ? 102.810 93.245  151.892 1.00 69.92  ? 137 TYR B CD1 1 
ATOM 2640 C CD2 . TYR B 1 63  ? 104.419 94.353  153.250 1.00 64.07  ? 137 TYR B CD2 1 
ATOM 2641 C CE1 . TYR B 1 63  ? 103.147 92.037  152.471 1.00 72.06  ? 137 TYR B CE1 1 
ATOM 2642 C CE2 . TYR B 1 63  ? 104.764 93.153  153.833 1.00 66.53  ? 137 TYR B CE2 1 
ATOM 2643 C CZ  . TYR B 1 63  ? 104.125 91.998  153.442 1.00 72.37  ? 137 TYR B CZ  1 
ATOM 2644 O OH  . TYR B 1 63  ? 104.466 90.798  154.023 1.00 75.98  ? 137 TYR B OH  1 
ATOM 2645 N N   . VAL B 1 64  ? 101.651 98.409  152.897 1.00 44.91  ? 138 VAL B N   1 
ATOM 2646 C CA  . VAL B 1 64  ? 101.695 99.865  152.943 1.00 56.93  ? 138 VAL B CA  1 
ATOM 2647 C C   . VAL B 1 64  ? 102.761 100.258 153.954 1.00 64.66  ? 138 VAL B C   1 
ATOM 2648 O O   . VAL B 1 64  ? 102.959 99.563  154.957 1.00 68.89  ? 138 VAL B O   1 
ATOM 2649 C CB  . VAL B 1 64  ? 100.320 100.468 153.314 1.00 67.73  ? 138 VAL B CB  1 
ATOM 2650 C CG1 . VAL B 1 64  ? 100.405 101.981 153.463 1.00 69.94  ? 138 VAL B CG1 1 
ATOM 2651 C CG2 . VAL B 1 64  ? 99.275  100.101 152.271 1.00 62.74  ? 138 VAL B CG2 1 
ATOM 2652 N N   . GLU B 1 65  ? 103.464 101.355 153.681 1.00 74.19  ? 139 GLU B N   1 
ATOM 2653 C CA  . GLU B 1 65  ? 104.461 101.847 154.621 1.00 75.51  ? 139 GLU B CA  1 
ATOM 2654 C C   . GLU B 1 65  ? 103.817 102.108 155.977 1.00 76.94  ? 139 GLU B C   1 
ATOM 2655 O O   . GLU B 1 65  ? 102.726 102.678 156.066 1.00 79.56  ? 139 GLU B O   1 
ATOM 2656 C CB  . GLU B 1 65  ? 105.114 103.121 154.086 1.00 73.25  ? 139 GLU B CB  1 
ATOM 2657 C CG  . GLU B 1 65  ? 106.430 103.472 154.758 1.00 74.30  ? 139 GLU B CG  1 
ATOM 2658 C CD  . GLU B 1 65  ? 107.546 102.508 154.401 1.00 81.24  ? 139 GLU B CD  1 
ATOM 2659 O OE1 . GLU B 1 65  ? 107.437 101.824 153.361 1.00 80.53  ? 139 GLU B OE1 1 
ATOM 2660 O OE2 . GLU B 1 65  ? 108.534 102.433 155.161 1.00 82.42  ? 139 GLU B OE2 1 
ATOM 2661 N N   . LYS B 1 66  ? 104.500 101.673 157.039 1.00 69.83  ? 140 LYS B N   1 
ATOM 2662 C CA  . LYS B 1 66  ? 103.911 101.725 158.374 1.00 67.67  ? 140 LYS B CA  1 
ATOM 2663 C C   . LYS B 1 66  ? 103.636 103.158 158.811 1.00 62.44  ? 140 LYS B C   1 
ATOM 2664 O O   . LYS B 1 66  ? 102.713 103.408 159.594 1.00 64.08  ? 140 LYS B O   1 
ATOM 2665 C CB  . LYS B 1 66  ? 104.824 101.015 159.375 1.00 67.96  ? 140 LYS B CB  1 
ATOM 2666 C CG  . LYS B 1 66  ? 106.166 101.693 159.603 1.00 68.43  ? 140 LYS B CG  1 
ATOM 2667 C CD  . LYS B 1 66  ? 107.020 100.907 160.586 1.00 61.04  ? 140 LYS B CD  1 
ATOM 2668 C CE  . LYS B 1 66  ? 108.381 101.556 160.781 1.00 60.56  ? 140 LYS B CE  1 
ATOM 2669 N NZ  . LYS B 1 66  ? 108.277 102.878 161.459 1.00 63.76  ? 140 LYS B NZ  1 
ATOM 2670 N N   . LYS B 1 67  ? 104.422 104.114 158.317 1.00 72.76  ? 141 LYS B N   1 
ATOM 2671 C CA  . LYS B 1 67  ? 104.209 105.509 158.676 1.00 75.88  ? 141 LYS B CA  1 
ATOM 2672 C C   . LYS B 1 67  ? 103.129 106.175 157.834 1.00 73.98  ? 141 LYS B C   1 
ATOM 2673 O O   . LYS B 1 67  ? 102.686 107.275 158.180 1.00 73.61  ? 141 LYS B O   1 
ATOM 2674 C CB  . LYS B 1 67  ? 105.519 106.292 158.553 1.00 79.39  ? 141 LYS B CB  1 
ATOM 2675 C CG  . LYS B 1 67  ? 106.034 106.433 157.131 1.00 79.71  ? 141 LYS B CG  1 
ATOM 2676 C CD  . LYS B 1 67  ? 107.349 107.195 157.097 1.00 78.96  ? 141 LYS B CD  1 
ATOM 2677 C CE  . LYS B 1 67  ? 107.890 107.301 155.681 1.00 77.56  ? 141 LYS B CE  1 
ATOM 2678 N NZ  . LYS B 1 67  ? 107.018 108.146 154.818 1.00 76.65  ? 141 LYS B NZ  1 
ATOM 2679 N N   . VAL B 1 68  ? 102.701 105.544 156.739 1.00 78.65  ? 142 VAL B N   1 
ATOM 2680 C CA  . VAL B 1 68  ? 101.639 106.125 155.924 1.00 78.04  ? 142 VAL B CA  1 
ATOM 2681 C C   . VAL B 1 68  ? 100.304 106.052 156.653 1.00 79.61  ? 142 VAL B C   1 
ATOM 2682 O O   . VAL B 1 68  ? 99.544  107.027 156.683 1.00 82.44  ? 142 VAL B O   1 
ATOM 2683 C CB  . VAL B 1 68  ? 101.577 105.434 154.550 1.00 82.94  ? 142 VAL B CB  1 
ATOM 2684 C CG1 . VAL B 1 68  ? 100.272 105.765 153.844 1.00 83.67  ? 142 VAL B CG1 1 
ATOM 2685 C CG2 . VAL B 1 68  ? 102.764 105.853 153.697 1.00 83.26  ? 142 VAL B CG2 1 
ATOM 2686 N N   . LEU B 1 69  ? 99.999  104.907 157.263 1.00 86.81  ? 143 LEU B N   1 
ATOM 2687 C CA  . LEU B 1 69  ? 98.731  104.731 157.972 1.00 88.53  ? 143 LEU B CA  1 
ATOM 2688 C C   . LEU B 1 69  ? 98.751  105.285 159.396 1.00 90.75  ? 143 LEU B C   1 
ATOM 2689 O O   . LEU B 1 69  ? 98.333  104.623 160.346 1.00 90.39  ? 143 LEU B O   1 
ATOM 2690 C CB  . LEU B 1 69  ? 98.358  103.247 157.937 1.00 89.12  ? 143 LEU B CB  1 
ATOM 2691 C CG  . LEU B 1 69  ? 99.282  102.127 158.452 1.00 89.00  ? 143 LEU B CG  1 
ATOM 2692 C CD1 . LEU B 1 69  ? 99.164  101.814 159.942 1.00 89.67  ? 143 LEU B CD1 1 
ATOM 2693 C CD2 . LEU B 1 69  ? 99.070  100.862 157.626 1.00 85.61  ? 143 LEU B CD2 1 
ATOM 2694 N N   . GLU B 1 70  ? 99.190  106.536 159.555 1.00 91.75  ? 144 GLU B N   1 
ATOM 2695 C CA  . GLU B 1 70  ? 99.113  107.212 160.843 1.00 86.65  ? 144 GLU B CA  1 
ATOM 2696 C C   . GLU B 1 70  ? 98.880  108.709 160.694 1.00 86.36  ? 144 GLU B C   1 
ATOM 2697 O O   . GLU B 1 70  ? 98.878  109.423 161.705 1.00 88.33  ? 144 GLU B O   1 
ATOM 2698 C CB  . GLU B 1 70  ? 100.382 106.970 161.669 1.00 88.65  ? 144 GLU B CB  1 
ATOM 2699 C CG  . GLU B 1 70  ? 101.613 107.696 161.155 1.00 93.09  ? 144 GLU B CG  1 
ATOM 2700 C CD  . GLU B 1 70  ? 102.838 107.439 162.011 1.00 94.74  ? 144 GLU B CD  1 
ATOM 2701 O OE1 . GLU B 1 70  ? 102.726 106.673 162.991 1.00 91.68  ? 144 GLU B OE1 1 
ATOM 2702 O OE2 . GLU B 1 70  ? 103.909 108.006 161.709 1.00 96.80  ? 144 GLU B OE2 1 
ATOM 2703 N N   . ASP B 1 71  ? 98.694  109.207 159.475 1.00 97.09  ? 145 ASP B N   1 
ATOM 2704 C CA  . ASP B 1 71  ? 98.464  110.626 159.272 1.00 98.29  ? 145 ASP B CA  1 
ATOM 2705 C C   . ASP B 1 71  ? 97.091  111.027 159.807 1.00 99.36  ? 145 ASP B C   1 
ATOM 2706 O O   . ASP B 1 71  ? 96.181  110.199 159.890 1.00 100.62 ? 145 ASP B O   1 
ATOM 2707 C CB  . ASP B 1 71  ? 98.565  110.977 157.790 1.00 98.06  ? 145 ASP B CB  1 
ATOM 2708 C CG  . ASP B 1 71  ? 99.904  110.598 157.191 1.00 99.12  ? 145 ASP B CG  1 
ATOM 2709 O OD1 . ASP B 1 71  ? 100.762 110.074 157.932 1.00 100.20 ? 145 ASP B OD1 1 
ATOM 2710 O OD2 . ASP B 1 71  ? 100.099 110.827 155.979 1.00 99.64  ? 145 ASP B OD2 1 
ATOM 2711 N N   . PRO B 1 72  ? 96.923  112.293 160.199 1.00 109.54 ? 146 PRO B N   1 
ATOM 2712 C CA  . PRO B 1 72  ? 95.587  112.744 160.624 1.00 109.33 ? 146 PRO B CA  1 
ATOM 2713 C C   . PRO B 1 72  ? 94.535  112.593 159.541 1.00 106.88 ? 146 PRO B C   1 
ATOM 2714 O O   . PRO B 1 72  ? 93.370  112.317 159.850 1.00 107.95 ? 146 PRO B O   1 
ATOM 2715 C CB  . PRO B 1 72  ? 95.816  114.217 160.999 1.00 110.62 ? 146 PRO B CB  1 
ATOM 2716 C CG  . PRO B 1 72  ? 97.104  114.598 160.331 1.00 110.47 ? 146 PRO B CG  1 
ATOM 2717 C CD  . PRO B 1 72  ? 97.933  113.356 160.329 1.00 109.33 ? 146 PRO B CD  1 
ATOM 2718 N N   . ALA B 1 73  ? 94.914  112.769 158.273 1.00 99.71  ? 147 ALA B N   1 
ATOM 2719 C CA  . ALA B 1 73  ? 93.952  112.630 157.185 1.00 102.04 ? 147 ALA B CA  1 
ATOM 2720 C C   . ALA B 1 73  ? 93.439  111.199 157.071 1.00 103.08 ? 147 ALA B C   1 
ATOM 2721 O O   . ALA B 1 73  ? 92.240  110.980 156.866 1.00 100.20 ? 147 ALA B O   1 
ATOM 2722 C CB  . ALA B 1 73  ? 94.582  113.080 155.867 1.00 102.99 ? 147 ALA B CB  1 
ATOM 2723 N N   . ILE B 1 74  ? 94.329  110.214 157.197 1.00 106.92 ? 148 ILE B N   1 
ATOM 2724 C CA  . ILE B 1 74  ? 93.905  108.825 157.055 1.00 105.16 ? 148 ILE B CA  1 
ATOM 2725 C C   . ILE B 1 74  ? 93.222  108.324 158.325 1.00 105.76 ? 148 ILE B C   1 
ATOM 2726 O O   . ILE B 1 74  ? 92.349  107.451 158.260 1.00 107.13 ? 148 ILE B O   1 
ATOM 2727 C CB  . ILE B 1 74  ? 95.101  107.938 156.660 1.00 104.70 ? 148 ILE B CB  1 
ATOM 2728 C CG1 . ILE B 1 74  ? 94.621  106.564 156.189 1.00 106.64 ? 148 ILE B CG1 1 
ATOM 2729 C CG2 . ILE B 1 74  ? 96.085  107.792 157.810 1.00 101.18 ? 148 ILE B CG2 1 
ATOM 2730 C CD1 . ILE B 1 74  ? 93.828  106.602 154.908 1.00 107.08 ? 148 ILE B CD1 1 
ATOM 2731 N N   . ALA B 1 75  ? 93.594  108.858 159.490 1.00 111.20 ? 149 ALA B N   1 
ATOM 2732 C CA  . ALA B 1 75  ? 92.961  108.437 160.735 1.00 111.74 ? 149 ALA B CA  1 
ATOM 2733 C C   . ALA B 1 75  ? 91.577  109.054 160.903 1.00 113.30 ? 149 ALA B C   1 
ATOM 2734 O O   . ALA B 1 75  ? 90.656  108.391 161.393 1.00 111.70 ? 149 ALA B O   1 
ATOM 2735 C CB  . ALA B 1 75  ? 93.852  108.794 161.925 1.00 112.85 ? 149 ALA B CB  1 
ATOM 2736 N N   . SER B 1 76  ? 91.415  110.319 160.507 1.00 120.78 ? 150 SER B N   1 
ATOM 2737 C CA  . SER B 1 76  ? 90.137  111.000 160.695 1.00 119.59 ? 150 SER B CA  1 
ATOM 2738 C C   . SER B 1 76  ? 89.033  110.360 159.862 1.00 118.98 ? 150 SER B C   1 
ATOM 2739 O O   . SER B 1 76  ? 87.898  110.219 160.332 1.00 117.94 ? 150 SER B O   1 
ATOM 2740 C CB  . SER B 1 76  ? 90.273  112.483 160.349 1.00 119.15 ? 150 SER B CB  1 
ATOM 2741 O OG  . SER B 1 76  ? 91.266  113.104 161.146 1.00 118.77 ? 150 SER B OG  1 
ATOM 2742 N N   . ASP B 1 77  ? 89.342  109.969 158.629 1.00 122.87 ? 151 ASP B N   1 
ATOM 2743 C CA  . ASP B 1 77  ? 88.344  109.400 157.727 1.00 124.67 ? 151 ASP B CA  1 
ATOM 2744 C C   . ASP B 1 77  ? 87.945  108.022 158.238 1.00 124.46 ? 151 ASP B C   1 
ATOM 2745 O O   . ASP B 1 77  ? 88.678  107.045 158.073 1.00 124.52 ? 151 ASP B O   1 
ATOM 2746 C CB  . ASP B 1 77  ? 88.894  109.325 156.307 1.00 122.78 ? 151 ASP B CB  1 
ATOM 2747 C CG  . ASP B 1 77  ? 87.829  108.972 155.285 1.00 122.28 ? 151 ASP B CG  1 
ATOM 2748 O OD1 . ASP B 1 77  ? 86.638  108.914 155.655 1.00 120.96 ? 151 ASP B OD1 1 
ATOM 2749 O OD2 . ASP B 1 77  ? 88.185  108.752 154.108 1.00 122.62 ? 151 ASP B OD2 1 
ATOM 2750 N N   . GLU B 1 78  ? 86.770  107.940 158.865 1.00 121.51 ? 152 GLU B N   1 
ATOM 2751 C CA  . GLU B 1 78  ? 86.268  106.668 159.366 1.00 121.36 ? 152 GLU B CA  1 
ATOM 2752 C C   . GLU B 1 78  ? 85.696  105.790 158.262 1.00 119.12 ? 152 GLU B C   1 
ATOM 2753 O O   . GLU B 1 78  ? 85.549  104.580 158.466 1.00 118.96 ? 152 GLU B O   1 
ATOM 2754 C CB  . GLU B 1 78  ? 85.202  106.901 160.441 1.00 121.63 ? 152 GLU B CB  1 
ATOM 2755 C CG  . GLU B 1 78  ? 83.932  107.581 159.941 1.00 120.63 ? 152 GLU B CG  1 
ATOM 2756 C CD  . GLU B 1 78  ? 84.085  109.083 159.788 1.00 121.27 ? 152 GLU B CD  1 
ATOM 2757 O OE1 . GLU B 1 78  ? 85.108  109.629 160.250 1.00 122.28 ? 152 GLU B OE1 1 
ATOM 2758 O OE2 . GLU B 1 78  ? 83.181  109.717 159.204 1.00 120.38 ? 152 GLU B OE2 1 
ATOM 2759 N N   . SER B 1 79  ? 85.367  106.369 157.106 1.00 105.78 ? 153 SER B N   1 
ATOM 2760 C CA  . SER B 1 79  ? 84.830  105.573 156.007 1.00 106.12 ? 153 SER B CA  1 
ATOM 2761 C C   . SER B 1 79  ? 85.855  104.568 155.501 1.00 107.79 ? 153 SER B C   1 
ATOM 2762 O O   . SER B 1 79  ? 85.515  103.415 155.211 1.00 106.53 ? 153 SER B O   1 
ATOM 2763 C CB  . SER B 1 79  ? 84.369  106.489 154.874 1.00 106.10 ? 153 SER B CB  1 
ATOM 2764 O OG  . SER B 1 79  ? 83.834  105.737 153.800 1.00 108.05 ? 153 SER B OG  1 
ATOM 2765 N N   . PHE B 1 80  ? 87.116  104.983 155.393 1.00 107.09 ? 154 PHE B N   1 
ATOM 2766 C CA  . PHE B 1 80  ? 88.180  104.106 154.923 1.00 106.62 ? 154 PHE B CA  1 
ATOM 2767 C C   . PHE B 1 80  ? 88.697  103.164 156.002 1.00 104.67 ? 154 PHE B C   1 
ATOM 2768 O O   . PHE B 1 80  ? 89.523  102.296 155.699 1.00 104.58 ? 154 PHE B O   1 
ATOM 2769 C CB  . PHE B 1 80  ? 89.339  104.935 154.363 1.00 103.58 ? 154 PHE B CB  1 
ATOM 2770 C CG  . PHE B 1 80  ? 90.300  104.142 153.526 1.00 105.44 ? 154 PHE B CG  1 
ATOM 2771 C CD1 . PHE B 1 80  ? 89.895  103.581 152.327 1.00 105.98 ? 154 PHE B CD1 1 
ATOM 2772 C CD2 . PHE B 1 80  ? 91.609  103.957 153.938 1.00 105.79 ? 154 PHE B CD2 1 
ATOM 2773 C CE1 . PHE B 1 80  ? 90.777  102.847 151.558 1.00 107.46 ? 154 PHE B CE1 1 
ATOM 2774 C CE2 . PHE B 1 80  ? 92.495  103.228 153.173 1.00 104.09 ? 154 PHE B CE2 1 
ATOM 2775 C CZ  . PHE B 1 80  ? 92.080  102.673 151.980 1.00 105.59 ? 154 PHE B CZ  1 
ATOM 2776 N N   . GLY B 1 81  ? 88.229  103.301 157.242 1.00 96.74  ? 155 GLY B N   1 
ATOM 2777 C CA  . GLY B 1 81  ? 88.684  102.434 158.312 1.00 97.81  ? 155 GLY B CA  1 
ATOM 2778 C C   . GLY B 1 81  ? 88.296  100.980 158.152 1.00 96.99  ? 155 GLY B C   1 
ATOM 2779 O O   . GLY B 1 81  ? 88.808  100.138 158.898 1.00 98.54  ? 155 GLY B O   1 
ATOM 2780 N N   . ALA B 1 82  ? 87.406  100.668 157.207 1.00 87.07  ? 156 ALA B N   1 
ATOM 2781 C CA  . ALA B 1 82  ? 86.997  99.284  157.003 1.00 89.87  ? 156 ALA B CA  1 
ATOM 2782 C C   . ALA B 1 82  ? 88.170  98.415  156.568 1.00 91.59  ? 156 ALA B C   1 
ATOM 2783 O O   . ALA B 1 82  ? 88.328  97.287  157.049 1.00 94.18  ? 156 ALA B O   1 
ATOM 2784 C CB  . ALA B 1 82  ? 85.869  99.217  155.974 1.00 91.38  ? 156 ALA B CB  1 
ATOM 2785 N N   . VAL B 1 83  ? 89.008  98.923  155.662 1.00 95.32  ? 157 VAL B N   1 
ATOM 2786 C CA  . VAL B 1 83  ? 90.127  98.147  155.136 1.00 97.56  ? 157 VAL B CA  1 
ATOM 2787 C C   . VAL B 1 83  ? 91.467  98.556  155.730 1.00 94.63  ? 157 VAL B C   1 
ATOM 2788 O O   . VAL B 1 83  ? 92.481  97.899  155.440 1.00 94.39  ? 157 VAL B O   1 
ATOM 2789 C CB  . VAL B 1 83  ? 90.196  98.240  153.597 1.00 99.16  ? 157 VAL B CB  1 
ATOM 2790 C CG1 . VAL B 1 83  ? 88.958  97.613  152.974 1.00 96.95  ? 157 VAL B CG1 1 
ATOM 2791 C CG2 . VAL B 1 83  ? 90.349  99.687  153.161 1.00 98.12  ? 157 VAL B CG2 1 
ATOM 2792 N N   . LYS B 1 84  ? 91.511  99.612  156.545 1.00 90.98  ? 158 LYS B N   1 
ATOM 2793 C CA  . LYS B 1 84  ? 92.777  100.049 157.125 1.00 92.76  ? 158 LYS B CA  1 
ATOM 2794 C C   . LYS B 1 84  ? 93.399  98.958  157.987 1.00 93.47  ? 158 LYS B C   1 
ATOM 2795 O O   . LYS B 1 84  ? 94.627  98.885  158.119 1.00 95.53  ? 158 LYS B O   1 
ATOM 2796 C CB  . LYS B 1 84  ? 92.569  101.323 157.944 1.00 95.36  ? 158 LYS B CB  1 
ATOM 2797 C CG  . LYS B 1 84  ? 92.483  102.590 157.110 1.00 96.29  ? 158 LYS B CG  1 
ATOM 2798 C CD  . LYS B 1 84  ? 92.599  103.836 157.974 1.00 96.00  ? 158 LYS B CD  1 
ATOM 2799 C CE  . LYS B 1 84  ? 93.965  103.927 158.637 1.00 95.69  ? 158 LYS B CE  1 
ATOM 2800 N NZ  . LYS B 1 84  ? 94.132  105.199 159.394 1.00 96.02  ? 158 LYS B NZ  1 
ATOM 2801 N N   . LYS B 1 85  ? 92.569  98.100  158.581 1.00 100.92 ? 159 LYS B N   1 
ATOM 2802 C CA  . LYS B 1 85  ? 93.094  97.028  159.419 1.00 103.59 ? 159 LYS B CA  1 
ATOM 2803 C C   . LYS B 1 85  ? 93.760  95.941  158.584 1.00 101.87 ? 159 LYS B C   1 
ATOM 2804 O O   . LYS B 1 85  ? 94.670  95.258  159.069 1.00 102.47 ? 159 LYS B O   1 
ATOM 2805 C CB  . LYS B 1 85  ? 91.968  96.442  160.276 1.00 103.33 ? 159 LYS B CB  1 
ATOM 2806 C CG  . LYS B 1 85  ? 92.376  95.286  161.184 1.00 102.70 ? 159 LYS B CG  1 
ATOM 2807 C CD  . LYS B 1 85  ? 91.974  93.938  160.601 1.00 102.49 ? 159 LYS B CD  1 
ATOM 2808 C CE  . LYS B 1 85  ? 92.483  92.791  161.460 1.00 102.34 ? 159 LYS B CE  1 
ATOM 2809 N NZ  . LYS B 1 85  ? 92.150  91.463  160.873 1.00 101.74 ? 159 LYS B NZ  1 
ATOM 2810 N N   . LYS B 1 86  ? 93.340  95.777  157.330 1.00 88.55  ? 160 LYS B N   1 
ATOM 2811 C CA  . LYS B 1 86  ? 93.828  94.677  156.509 1.00 91.04  ? 160 LYS B CA  1 
ATOM 2812 C C   . LYS B 1 86  ? 95.190  94.949  155.882 1.00 95.40  ? 160 LYS B C   1 
ATOM 2813 O O   . LYS B 1 86  ? 95.751  94.045  155.254 1.00 96.78  ? 160 LYS B O   1 
ATOM 2814 C CB  . LYS B 1 86  ? 92.808  94.351  155.417 1.00 91.13  ? 160 LYS B CB  1 
ATOM 2815 C CG  . LYS B 1 86  ? 91.397  94.156  155.947 1.00 90.69  ? 160 LYS B CG  1 
ATOM 2816 C CD  . LYS B 1 86  ? 90.401  93.940  154.824 1.00 91.17  ? 160 LYS B CD  1 
ATOM 2817 C CE  . LYS B 1 86  ? 90.709  92.666  154.058 1.00 92.17  ? 160 LYS B CE  1 
ATOM 2818 N NZ  . LYS B 1 86  ? 89.752  92.447  152.938 1.00 91.18  ? 160 LYS B NZ  1 
ATOM 2819 N N   . PHE B 1 87  ? 95.731  96.156  156.028 1.00 74.95  ? 161 PHE B N   1 
ATOM 2820 C CA  . PHE B 1 87  ? 97.070  96.438  155.531 1.00 59.32  ? 161 PHE B CA  1 
ATOM 2821 C C   . PHE B 1 87  ? 98.104  95.645  156.319 1.00 62.10  ? 161 PHE B C   1 
ATOM 2822 O O   . PHE B 1 87  ? 97.935  95.390  157.515 1.00 70.98  ? 161 PHE B O   1 
ATOM 2823 C CB  . PHE B 1 87  ? 97.377  97.931  155.633 1.00 59.17  ? 161 PHE B CB  1 
ATOM 2824 C CG  . PHE B 1 87  ? 96.573  98.784  154.697 1.00 67.78  ? 161 PHE B CG  1 
ATOM 2825 C CD1 . PHE B 1 87  ? 96.015  98.246  153.551 1.00 74.57  ? 161 PHE B CD1 1 
ATOM 2826 C CD2 . PHE B 1 87  ? 96.382  100.129 154.963 1.00 69.49  ? 161 PHE B CD2 1 
ATOM 2827 C CE1 . PHE B 1 87  ? 95.276  99.034  152.689 1.00 73.94  ? 161 PHE B CE1 1 
ATOM 2828 C CE2 . PHE B 1 87  ? 95.646  100.921 154.107 1.00 69.93  ? 161 PHE B CE2 1 
ATOM 2829 C CZ  . PHE B 1 87  ? 95.091  100.373 152.968 1.00 71.55  ? 161 PHE B CZ  1 
ATOM 2830 N N   . THR B 1 88  ? 99.180  95.255  155.646 1.00 55.32  ? 162 THR B N   1 
ATOM 2831 C CA  . THR B 1 88  ? 100.256 94.521  156.301 1.00 60.01  ? 162 THR B CA  1 
ATOM 2832 C C   . THR B 1 88  ? 101.526 95.362  156.376 1.00 60.19  ? 162 THR B C   1 
ATOM 2833 O O   . THR B 1 88  ? 101.758 96.070  157.356 1.00 57.60  ? 162 THR B O   1 
ATOM 2834 C CB  . THR B 1 88  ? 100.538 93.200  155.562 1.00 61.22  ? 162 THR B CB  1 
ATOM 2835 O OG1 . THR B 1 88  ? 99.366  92.379  155.581 1.00 62.70  ? 162 THR B OG1 1 
ATOM 2836 C CG2 . THR B 1 88  ? 101.560 92.370  156.324 1.00 57.12  ? 162 THR B CG2 1 
ATOM 2837 N N   . GLN B 1 100 ? 110.038 90.658  150.375 1.00 85.72  ? 174 GLN B N   1 
ATOM 2838 C CA  . GLN B 1 100 ? 108.857 89.840  150.142 1.00 91.40  ? 174 GLN B CA  1 
ATOM 2839 C C   . GLN B 1 100 ? 107.851 90.500  149.210 1.00 95.22  ? 174 GLN B C   1 
ATOM 2840 O O   . GLN B 1 100 ? 106.760 89.954  149.013 1.00 96.21  ? 174 GLN B O   1 
ATOM 2841 C CB  . GLN B 1 100 ? 108.178 89.497  151.475 1.00 91.44  ? 174 GLN B CB  1 
ATOM 2842 C CG  . GLN B 1 100 ? 107.570 90.690  152.200 1.00 92.59  ? 174 GLN B CG  1 
ATOM 2843 C CD  . GLN B 1 100 ? 108.592 91.481  152.996 1.00 94.15  ? 174 GLN B CD  1 
ATOM 2844 O OE1 . GLN B 1 100 ? 109.790 91.204  152.941 1.00 94.61  ? 174 GLN B OE1 1 
ATOM 2845 N NE2 . GLN B 1 100 ? 108.120 92.472  153.744 1.00 91.67  ? 174 GLN B NE2 1 
ATOM 2846 N N   . ILE B 1 101 ? 108.183 91.651  148.635 1.00 84.59  ? 175 ILE B N   1 
ATOM 2847 C CA  . ILE B 1 101 ? 107.270 92.356  147.742 1.00 81.73  ? 175 ILE B CA  1 
ATOM 2848 C C   . ILE B 1 101 ? 107.381 91.763  146.344 1.00 77.01  ? 175 ILE B C   1 
ATOM 2849 O O   . ILE B 1 101 ? 108.485 91.534  145.838 1.00 80.09  ? 175 ILE B O   1 
ATOM 2850 C CB  . ILE B 1 101 ? 107.572 93.862  147.735 1.00 80.49  ? 175 ILE B CB  1 
ATOM 2851 C CG1 . ILE B 1 101 ? 107.374 94.446  149.134 1.00 79.13  ? 175 ILE B CG1 1 
ATOM 2852 C CG2 . ILE B 1 101 ? 106.694 94.582  146.721 1.00 80.81  ? 175 ILE B CG2 1 
ATOM 2853 C CD1 . ILE B 1 101 ? 105.971 94.278  149.668 1.00 76.87  ? 175 ILE B CD1 1 
ATOM 2854 N N   . ASP B 1 102 ? 106.233 91.511  145.718 1.00 66.29  ? 176 ASP B N   1 
ATOM 2855 C CA  . ASP B 1 102 ? 106.193 90.939  144.380 1.00 71.14  ? 176 ASP B CA  1 
ATOM 2856 C C   . ASP B 1 102 ? 105.930 91.965  143.290 1.00 73.13  ? 176 ASP B C   1 
ATOM 2857 O O   . ASP B 1 102 ? 106.310 91.736  142.138 1.00 78.89  ? 176 ASP B O   1 
ATOM 2858 C CB  . ASP B 1 102 ? 105.122 89.847  144.302 1.00 76.91  ? 176 ASP B CB  1 
ATOM 2859 C CG  . ASP B 1 102 ? 105.411 88.682  145.225 1.00 79.95  ? 176 ASP B CG  1 
ATOM 2860 O OD1 . ASP B 1 102 ? 106.601 88.413  145.489 1.00 78.87  ? 176 ASP B OD1 1 
ATOM 2861 O OD2 . ASP B 1 102 ? 104.448 88.033  145.685 1.00 81.52  ? 176 ASP B OD2 1 
ATOM 2862 N N   . PHE B 1 103 ? 105.292 93.085  143.618 1.00 59.38  ? 177 PHE B N   1 
ATOM 2863 C CA  . PHE B 1 103 ? 104.969 94.092  142.618 1.00 59.60  ? 177 PHE B CA  1 
ATOM 2864 C C   . PHE B 1 103 ? 104.707 95.413  143.325 1.00 64.64  ? 177 PHE B C   1 
ATOM 2865 O O   . PHE B 1 103 ? 104.118 95.444  144.408 1.00 73.34  ? 177 PHE B O   1 
ATOM 2866 C CB  . PHE B 1 103 ? 103.760 93.662  141.779 1.00 63.52  ? 177 PHE B CB  1 
ATOM 2867 C CG  . PHE B 1 103 ? 103.263 94.716  140.837 1.00 65.47  ? 177 PHE B CG  1 
ATOM 2868 C CD1 . PHE B 1 103 ? 104.053 95.150  139.786 1.00 70.08  ? 177 PHE B CD1 1 
ATOM 2869 C CD2 . PHE B 1 103 ? 101.996 95.251  140.983 1.00 66.48  ? 177 PHE B CD2 1 
ATOM 2870 C CE1 . PHE B 1 103 ? 103.595 96.115  138.911 1.00 73.10  ? 177 PHE B CE1 1 
ATOM 2871 C CE2 . PHE B 1 103 ? 101.533 96.213  140.111 1.00 70.36  ? 177 PHE B CE2 1 
ATOM 2872 C CZ  . PHE B 1 103 ? 102.334 96.646  139.073 1.00 75.04  ? 177 PHE B CZ  1 
ATOM 2873 N N   . ILE B 1 104 ? 105.152 96.502  142.702 1.00 58.88  ? 178 ILE B N   1 
ATOM 2874 C CA  . ILE B 1 104 ? 105.137 97.827  143.310 1.00 57.03  ? 178 ILE B CA  1 
ATOM 2875 C C   . ILE B 1 104 ? 104.238 98.740  142.489 1.00 59.57  ? 178 ILE B C   1 
ATOM 2876 O O   . ILE B 1 104 ? 104.342 98.780  141.257 1.00 66.53  ? 178 ILE B O   1 
ATOM 2877 C CB  . ILE B 1 104 ? 106.555 98.417  143.415 1.00 51.57  ? 178 ILE B CB  1 
ATOM 2878 C CG1 . ILE B 1 104 ? 107.449 97.512  144.259 1.00 56.02  ? 178 ILE B CG1 1 
ATOM 2879 C CG2 . ILE B 1 104 ? 106.514 99.811  144.004 1.00 56.80  ? 178 ILE B CG2 1 
ATOM 2880 C CD1 . ILE B 1 104 ? 108.848 98.050  144.448 1.00 60.36  ? 178 ILE B CD1 1 
ATOM 2881 N N   . ILE B 1 105 ? 103.357 99.467  143.172 1.00 56.47  ? 179 ILE B N   1 
ATOM 2882 C CA  . ILE B 1 105 ? 102.530 100.504 142.567 1.00 49.10  ? 179 ILE B CA  1 
ATOM 2883 C C   . ILE B 1 105 ? 102.912 101.832 143.199 1.00 54.76  ? 179 ILE B C   1 
ATOM 2884 O O   . ILE B 1 105 ? 102.943 101.952 144.430 1.00 68.34  ? 179 ILE B O   1 
ATOM 2885 C CB  . ILE B 1 105 ? 101.029 100.224 142.753 1.00 61.12  ? 179 ILE B CB  1 
ATOM 2886 C CG1 . ILE B 1 105 ? 100.637 98.921  142.058 1.00 67.20  ? 179 ILE B CG1 1 
ATOM 2887 C CG2 . ILE B 1 105 ? 100.207 101.381 142.219 1.00 62.93  ? 179 ILE B CG2 1 
ATOM 2888 C CD1 . ILE B 1 105 ? 99.155  98.623  142.107 1.00 68.21  ? 179 ILE B CD1 1 
ATOM 2889 N N   . CYS B 1 106 ? 103.199 102.825 142.365 1.00 58.89  ? 180 CYS B N   1 
ATOM 2890 C CA  . CYS B 1 106 ? 103.689 104.116 142.823 1.00 60.14  ? 180 CYS B CA  1 
ATOM 2891 C C   . CYS B 1 106 ? 102.728 105.222 142.414 1.00 65.47  ? 180 CYS B C   1 
ATOM 2892 O O   . CYS B 1 106 ? 102.178 105.206 141.308 1.00 71.12  ? 180 CYS B O   1 
ATOM 2893 C CB  . CYS B 1 106 ? 105.080 104.405 142.256 1.00 67.43  ? 180 CYS B CB  1 
ATOM 2894 S SG  . CYS B 1 106 ? 106.399 103.414 142.985 1.00 83.79  ? 180 CYS B SG  1 
ATOM 2895 N N   . LEU B 1 107 ? 102.528 106.179 143.316 1.00 87.23  ? 181 LEU B N   1 
ATOM 2896 C CA  . LEU B 1 107 ? 101.722 107.363 143.058 1.00 89.46  ? 181 LEU B CA  1 
ATOM 2897 C C   . LEU B 1 107 ? 102.596 108.597 143.232 1.00 91.06  ? 181 LEU B C   1 
ATOM 2898 O O   . LEU B 1 107 ? 103.278 108.740 144.253 1.00 90.71  ? 181 LEU B O   1 
ATOM 2899 C CB  . LEU B 1 107 ? 100.516 107.423 143.998 1.00 88.66  ? 181 LEU B CB  1 
ATOM 2900 C CG  . LEU B 1 107 ? 99.568  106.224 143.944 1.00 88.18  ? 181 LEU B CG  1 
ATOM 2901 C CD1 . LEU B 1 107 ? 98.430  106.396 144.933 1.00 85.58  ? 181 LEU B CD1 1 
ATOM 2902 C CD2 . LEU B 1 107 ? 99.035  106.024 142.535 1.00 88.19  ? 181 LEU B CD2 1 
ATOM 2903 N N   . GLY B 1 108 ? 102.576 109.482 142.239 1.00 97.33  ? 182 GLY B N   1 
ATOM 2904 C CA  . GLY B 1 108 ? 103.414 110.666 142.261 1.00 96.12  ? 182 GLY B CA  1 
ATOM 2905 C C   . GLY B 1 108 ? 104.314 110.756 141.046 1.00 97.04  ? 182 GLY B C   1 
ATOM 2906 O O   . GLY B 1 108 ? 104.527 109.755 140.358 1.00 97.37  ? 182 GLY B O   1 
ATOM 2907 N N   . GLY B 1 109 ? 104.851 111.944 140.772 1.00 101.05 ? 183 GLY B N   1 
ATOM 2908 C CA  . GLY B 1 109 ? 105.644 112.145 139.574 1.00 102.33 ? 183 GLY B CA  1 
ATOM 2909 C C   . GLY B 1 109 ? 107.131 112.332 139.804 1.00 103.62 ? 183 GLY B C   1 
ATOM 2910 O O   . GLY B 1 109 ? 107.562 113.377 140.303 1.00 104.39 ? 183 GLY B O   1 
ATOM 2911 N N   . ASP B 1 110 ? 107.917 111.306 139.466 1.00 98.58  ? 184 ASP B N   1 
ATOM 2912 C CA  . ASP B 1 110 ? 109.377 111.367 139.429 1.00 96.60  ? 184 ASP B CA  1 
ATOM 2913 C C   . ASP B 1 110 ? 110.001 111.536 140.810 1.00 96.26  ? 184 ASP B C   1 
ATOM 2914 O O   . ASP B 1 110 ? 111.229 111.542 140.942 1.00 98.92  ? 184 ASP B O   1 
ATOM 2915 C CB  . ASP B 1 110 ? 109.848 112.494 138.504 1.00 96.77  ? 184 ASP B CB  1 
ATOM 2916 C CG  . ASP B 1 110 ? 109.546 112.214 137.046 1.00 97.33  ? 184 ASP B CG  1 
ATOM 2917 O OD1 . ASP B 1 110 ? 108.977 111.142 136.751 1.00 94.83  ? 184 ASP B OD1 1 
ATOM 2918 O OD2 . ASP B 1 110 ? 109.881 113.065 136.195 1.00 98.70  ? 184 ASP B OD2 1 
ATOM 2919 N N   . GLY B 1 111 ? 109.174 111.673 141.841 1.00 76.33  ? 185 GLY B N   1 
ATOM 2920 C CA  . GLY B 1 111 ? 109.645 111.749 143.204 1.00 70.79  ? 185 GLY B CA  1 
ATOM 2921 C C   . GLY B 1 111 ? 109.386 110.511 144.021 1.00 70.26  ? 185 GLY B C   1 
ATOM 2922 O O   . GLY B 1 111 ? 109.837 110.434 145.168 1.00 70.47  ? 185 GLY B O   1 
ATOM 2923 N N   . THR B 1 112 ? 108.675 109.533 143.466 1.00 70.06  ? 186 THR B N   1 
ATOM 2924 C CA  . THR B 1 112 ? 108.274 108.336 144.189 1.00 71.37  ? 186 THR B CA  1 
ATOM 2925 C C   . THR B 1 112 ? 109.157 107.134 143.883 1.00 70.84  ? 186 THR B C   1 
ATOM 2926 O O   . THR B 1 112 ? 109.474 106.360 144.791 1.00 70.88  ? 186 THR B O   1 
ATOM 2927 C CB  . THR B 1 112 ? 106.815 107.999 143.865 1.00 70.46  ? 186 THR B CB  1 
ATOM 2928 O OG1 . THR B 1 112 ? 105.981 109.106 144.224 1.00 72.77  ? 186 THR B OG1 1 
ATOM 2929 C CG2 . THR B 1 112 ? 106.362 106.782 144.644 1.00 70.60  ? 186 THR B CG2 1 
ATOM 2930 N N   . LEU B 1 113 ? 109.573 106.963 142.625 1.00 72.52  ? 187 LEU B N   1 
ATOM 2931 C CA  . LEU B 1 113 ? 110.432 105.833 142.285 1.00 71.69  ? 187 LEU B CA  1 
ATOM 2932 C C   . LEU B 1 113 ? 111.803 105.951 142.936 1.00 73.95  ? 187 LEU B C   1 
ATOM 2933 O O   . LEU B 1 113 ? 112.459 104.932 143.181 1.00 74.54  ? 187 LEU B O   1 
ATOM 2934 C CB  . LEU B 1 113 ? 110.577 105.707 140.769 1.00 61.84  ? 187 LEU B CB  1 
ATOM 2935 C CG  . LEU B 1 113 ? 109.389 105.075 140.046 1.00 64.73  ? 187 LEU B CG  1 
ATOM 2936 C CD1 . LEU B 1 113 ? 108.347 106.125 139.699 1.00 66.83  ? 187 LEU B CD1 1 
ATOM 2937 C CD2 . LEU B 1 113 ? 109.847 104.321 138.810 1.00 71.43  ? 187 LEU B CD2 1 
ATOM 2938 N N   . LEU B 1 114 ? 112.255 107.174 143.215 1.00 69.16  ? 188 LEU B N   1 
ATOM 2939 C CA  . LEU B 1 114 ? 113.478 107.341 143.990 1.00 64.55  ? 188 LEU B CA  1 
ATOM 2940 C C   . LEU B 1 114 ? 113.315 106.762 145.388 1.00 63.44  ? 188 LEU B C   1 
ATOM 2941 O O   . LEU B 1 114 ? 114.230 106.116 145.913 1.00 64.55  ? 188 LEU B O   1 
ATOM 2942 C CB  . LEU B 1 114 ? 113.860 108.819 144.056 1.00 65.53  ? 188 LEU B CB  1 
ATOM 2943 C CG  . LEU B 1 114 ? 114.309 109.415 142.724 1.00 64.79  ? 188 LEU B CG  1 
ATOM 2944 C CD1 . LEU B 1 114 ? 114.693 110.875 142.883 1.00 62.33  ? 188 LEU B CD1 1 
ATOM 2945 C CD2 . LEU B 1 114 ? 115.471 108.606 142.173 1.00 65.93  ? 188 LEU B CD2 1 
ATOM 2946 N N   . TYR B 1 115 ? 112.154 106.983 146.005 1.00 52.15  ? 189 TYR B N   1 
ATOM 2947 C CA  . TYR B 1 115 ? 111.871 106.356 147.290 1.00 52.71  ? 189 TYR B CA  1 
ATOM 2948 C C   . TYR B 1 115 ? 111.716 104.849 147.142 1.00 58.64  ? 189 TYR B C   1 
ATOM 2949 O O   . TYR B 1 115 ? 112.090 104.089 148.044 1.00 63.92  ? 189 TYR B O   1 
ATOM 2950 C CB  . TYR B 1 115 ? 110.617 106.971 147.906 1.00 54.15  ? 189 TYR B CB  1 
ATOM 2951 C CG  . TYR B 1 115 ? 110.234 106.380 149.240 1.00 53.11  ? 189 TYR B CG  1 
ATOM 2952 C CD1 . TYR B 1 115 ? 110.875 106.772 150.403 1.00 56.54  ? 189 TYR B CD1 1 
ATOM 2953 C CD2 . TYR B 1 115 ? 109.222 105.438 149.338 1.00 51.17  ? 189 TYR B CD2 1 
ATOM 2954 C CE1 . TYR B 1 115 ? 110.526 106.237 151.624 1.00 59.71  ? 189 TYR B CE1 1 
ATOM 2955 C CE2 . TYR B 1 115 ? 108.866 104.898 150.551 1.00 51.86  ? 189 TYR B CE2 1 
ATOM 2956 C CZ  . TYR B 1 115 ? 109.520 105.300 151.692 1.00 59.38  ? 189 TYR B CZ  1 
ATOM 2957 O OH  . TYR B 1 115 ? 109.166 104.763 152.907 1.00 62.99  ? 189 TYR B OH  1 
ATOM 2958 N N   . ALA B 1 116 ? 111.160 104.398 146.015 1.00 56.69  ? 190 ALA B N   1 
ATOM 2959 C CA  . ALA B 1 116 ? 111.022 102.965 145.784 1.00 57.64  ? 190 ALA B CA  1 
ATOM 2960 C C   . ALA B 1 116 ? 112.382 102.291 145.668 1.00 56.94  ? 190 ALA B C   1 
ATOM 2961 O O   . ALA B 1 116 ? 112.578 101.180 146.173 1.00 58.21  ? 190 ALA B O   1 
ATOM 2962 C CB  . ALA B 1 116 ? 110.189 102.713 144.528 1.00 58.85  ? 190 ALA B CB  1 
ATOM 2963 N N   . SER B 1 117 ? 113.335 102.947 145.001 1.00 61.85  ? 191 SER B N   1 
ATOM 2964 C CA  . SER B 1 117 ? 114.675 102.383 144.879 1.00 61.53  ? 191 SER B CA  1 
ATOM 2965 C C   . SER B 1 117 ? 115.351 102.268 146.238 1.00 64.17  ? 191 SER B C   1 
ATOM 2966 O O   . SER B 1 117 ? 116.095 101.314 146.491 1.00 67.26  ? 191 SER B O   1 
ATOM 2967 C CB  . SER B 1 117 ? 115.523 103.236 143.938 1.00 56.08  ? 191 SER B CB  1 
ATOM 2968 O OG  . SER B 1 117 ? 114.952 103.296 142.644 1.00 59.79  ? 191 SER B OG  1 
ATOM 2969 N N   . SER B 1 118 ? 115.111 103.240 147.121 1.00 62.64  ? 192 SER B N   1 
ATOM 2970 C CA  . SER B 1 118 ? 115.781 103.249 148.415 1.00 61.80  ? 192 SER B CA  1 
ATOM 2971 C C   . SER B 1 118 ? 115.405 102.030 149.246 1.00 61.16  ? 192 SER B C   1 
ATOM 2972 O O   . SER B 1 118 ? 116.265 101.426 149.898 1.00 66.56  ? 192 SER B O   1 
ATOM 2973 C CB  . SER B 1 118 ? 115.444 104.534 149.169 1.00 64.93  ? 192 SER B CB  1 
ATOM 2974 O OG  . SER B 1 118 ? 114.051 104.633 149.400 1.00 67.12  ? 192 SER B OG  1 
ATOM 2975 N N   . LEU B 1 119 ? 114.127 101.651 149.236 1.00 57.00  ? 193 LEU B N   1 
ATOM 2976 C CA  . LEU B 1 119 ? 113.693 100.525 150.053 1.00 62.48  ? 193 LEU B CA  1 
ATOM 2977 C C   . LEU B 1 119 ? 114.154 99.185  149.497 1.00 61.03  ? 193 LEU B C   1 
ATOM 2978 O O   . LEU B 1 119 ? 114.109 98.183  150.218 1.00 61.65  ? 193 LEU B O   1 
ATOM 2979 C CB  . LEU B 1 119 ? 112.171 100.528 150.198 1.00 58.01  ? 193 LEU B CB  1 
ATOM 2980 C CG  . LEU B 1 119 ? 111.554 101.745 150.885 1.00 58.49  ? 193 LEU B CG  1 
ATOM 2981 C CD1 . LEU B 1 119 ? 110.046 101.602 150.952 1.00 61.56  ? 193 LEU B CD1 1 
ATOM 2982 C CD2 . LEU B 1 119 ? 112.141 101.926 152.274 1.00 61.04  ? 193 LEU B CD2 1 
ATOM 2983 N N   . PHE B 1 120 ? 114.599 99.140  148.245 1.00 55.24  ? 194 PHE B N   1 
ATOM 2984 C CA  . PHE B 1 120 ? 115.007 97.896  147.598 1.00 60.63  ? 194 PHE B CA  1 
ATOM 2985 C C   . PHE B 1 120 ? 116.424 98.066  147.058 1.00 64.79  ? 194 PHE B C   1 
ATOM 2986 O O   . PHE B 1 120 ? 116.620 98.473  145.911 1.00 58.56  ? 194 PHE B O   1 
ATOM 2987 C CB  . PHE B 1 120 ? 114.028 97.512  146.493 1.00 60.87  ? 194 PHE B CB  1 
ATOM 2988 C CG  . PHE B 1 120 ? 112.653 97.180  146.992 1.00 60.43  ? 194 PHE B CG  1 
ATOM 2989 C CD1 . PHE B 1 120 ? 111.728 98.180  147.229 1.00 62.22  ? 194 PHE B CD1 1 
ATOM 2990 C CD2 . PHE B 1 120 ? 112.284 95.867  147.220 1.00 58.09  ? 194 PHE B CD2 1 
ATOM 2991 C CE1 . PHE B 1 120 ? 110.464 97.878  147.688 1.00 58.00  ? 194 PHE B CE1 1 
ATOM 2992 C CE2 . PHE B 1 120 ? 111.021 95.559  147.677 1.00 61.53  ? 194 PHE B CE2 1 
ATOM 2993 C CZ  . PHE B 1 120 ? 110.110 96.567  147.912 1.00 59.89  ? 194 PHE B CZ  1 
ATOM 2994 N N   . GLN B 1 121 ? 117.413 97.750  147.894 1.00 66.51  ? 195 GLN B N   1 
ATOM 2995 C CA  . GLN B 1 121 ? 118.804 97.756  147.463 1.00 64.14  ? 195 GLN B CA  1 
ATOM 2996 C C   . GLN B 1 121 ? 119.191 96.492  146.709 1.00 61.29  ? 195 GLN B C   1 
ATOM 2997 O O   . GLN B 1 121 ? 120.235 96.480  146.049 1.00 66.35  ? 195 GLN B O   1 
ATOM 2998 C CB  . GLN B 1 121 ? 119.727 97.936  148.670 1.00 64.78  ? 195 GLN B CB  1 
ATOM 2999 C CG  . GLN B 1 121 ? 119.502 99.227  149.431 1.00 64.65  ? 195 GLN B CG  1 
ATOM 3000 C CD  . GLN B 1 121 ? 119.852 100.450 148.612 1.00 65.26  ? 195 GLN B CD  1 
ATOM 3001 O OE1 . GLN B 1 121 ? 121.021 100.815 148.491 1.00 64.74  ? 195 GLN B OE1 1 
ATOM 3002 N NE2 . GLN B 1 121 ? 118.840 101.091 148.041 1.00 62.44  ? 195 GLN B NE2 1 
ATOM 3003 N N   . GLY B 1 122 ? 118.387 95.443  146.788 1.00 50.70  ? 196 GLY B N   1 
ATOM 3004 C CA  . GLY B 1 122 ? 118.609 94.211  146.057 1.00 54.76  ? 196 GLY B CA  1 
ATOM 3005 C C   . GLY B 1 122 ? 117.800 94.166  144.780 1.00 64.20  ? 196 GLY B C   1 
ATOM 3006 O O   . GLY B 1 122 ? 117.717 95.152  144.039 1.00 68.68  ? 196 GLY B O   1 
ATOM 3007 N N   . SER B 1 123 ? 117.191 93.013  144.518 1.00 66.36  ? 197 SER B N   1 
ATOM 3008 C CA  . SER B 1 123 ? 116.356 92.848  143.334 1.00 61.88  ? 197 SER B CA  1 
ATOM 3009 C C   . SER B 1 123 ? 115.005 93.509  143.575 1.00 65.93  ? 197 SER B C   1 
ATOM 3010 O O   . SER B 1 123 ? 114.220 93.050  144.410 1.00 72.89  ? 197 SER B O   1 
ATOM 3011 C CB  . SER B 1 123 ? 116.190 91.368  143.007 1.00 63.17  ? 197 SER B CB  1 
ATOM 3012 O OG  . SER B 1 123 ? 115.594 90.672  144.087 1.00 71.10  ? 197 SER B OG  1 
ATOM 3013 N N   . VAL B 1 124 ? 114.729 94.586  142.846 1.00 54.78  ? 198 VAL B N   1 
ATOM 3014 C CA  . VAL B 1 124 ? 113.478 95.324  143.002 1.00 59.50  ? 198 VAL B CA  1 
ATOM 3015 C C   . VAL B 1 124 ? 112.436 94.747  142.049 1.00 60.89  ? 198 VAL B C   1 
ATOM 3016 O O   . VAL B 1 124 ? 112.739 94.485  140.876 1.00 62.41  ? 198 VAL B O   1 
ATOM 3017 C CB  . VAL B 1 124 ? 113.696 96.834  142.791 1.00 48.80  ? 198 VAL B CB  1 
ATOM 3018 C CG1 . VAL B 1 124 ? 114.168 97.127  141.385 1.00 51.50  ? 198 VAL B CG1 1 
ATOM 3019 C CG2 . VAL B 1 124 ? 112.427 97.611  143.097 1.00 51.99  ? 198 VAL B CG2 1 
ATOM 3020 N N   . PRO B 1 125 ? 111.217 94.492  142.515 1.00 58.73  ? 199 PRO B N   1 
ATOM 3021 C CA  . PRO B 1 125 ? 110.181 93.933  141.640 1.00 55.54  ? 199 PRO B CA  1 
ATOM 3022 C C   . PRO B 1 125 ? 109.715 94.962  140.626 1.00 57.38  ? 199 PRO B C   1 
ATOM 3023 O O   . PRO B 1 125 ? 110.125 96.131  140.689 1.00 64.97  ? 199 PRO B O   1 
ATOM 3024 C CB  . PRO B 1 125 ? 109.058 93.562  142.623 1.00 63.49  ? 199 PRO B CB  1 
ATOM 3025 C CG  . PRO B 1 125 ? 109.286 94.425  143.807 1.00 61.73  ? 199 PRO B CG  1 
ATOM 3026 C CD  . PRO B 1 125 ? 110.766 94.597  143.913 1.00 59.34  ? 199 PRO B CD  1 
ATOM 3027 N N   . PRO B 1 126 ? 108.875 94.569  139.665 1.00 51.18  ? 200 PRO B N   1 
ATOM 3028 C CA  . PRO B 1 126 ? 108.364 95.545  138.696 1.00 55.94  ? 200 PRO B CA  1 
ATOM 3029 C C   . PRO B 1 126 ? 107.634 96.689  139.383 1.00 59.00  ? 200 PRO B C   1 
ATOM 3030 O O   . PRO B 1 126 ? 106.913 96.494  140.363 1.00 65.51  ? 200 PRO B O   1 
ATOM 3031 C CB  . PRO B 1 126 ? 107.416 94.715  137.826 1.00 60.85  ? 200 PRO B CB  1 
ATOM 3032 C CG  . PRO B 1 126 ? 107.949 93.339  137.916 1.00 60.75  ? 200 PRO B CG  1 
ATOM 3033 C CD  . PRO B 1 126 ? 108.487 93.193  139.307 1.00 56.71  ? 200 PRO B CD  1 
ATOM 3034 N N   . VAL B 1 127 ? 107.831 97.892  138.854 1.00 59.90  ? 201 VAL B N   1 
ATOM 3035 C CA  . VAL B 1 127 ? 107.291 99.115  139.431 1.00 58.44  ? 201 VAL B CA  1 
ATOM 3036 C C   . VAL B 1 127 ? 106.391 99.778  138.402 1.00 56.94  ? 201 VAL B C   1 
ATOM 3037 O O   . VAL B 1 127 ? 106.818 100.039 137.272 1.00 70.40  ? 201 VAL B O   1 
ATOM 3038 C CB  . VAL B 1 127 ? 108.410 100.076 139.872 1.00 67.37  ? 201 VAL B CB  1 
ATOM 3039 C CG1 . VAL B 1 127 ? 107.821 101.393 140.342 1.00 68.15  ? 201 VAL B CG1 1 
ATOM 3040 C CG2 . VAL B 1 127 ? 109.252 99.443  140.967 1.00 68.34  ? 201 VAL B CG2 1 
ATOM 3041 N N   . MET B 1 128 ? 105.151 100.048 138.793 1.00 55.97  ? 202 MET B N   1 
ATOM 3042 C CA  . MET B 1 128 ? 104.192 100.751 137.956 1.00 64.66  ? 202 MET B CA  1 
ATOM 3043 C C   . MET B 1 128 ? 103.836 102.064 138.633 1.00 62.64  ? 202 MET B C   1 
ATOM 3044 O O   . MET B 1 128 ? 103.438 102.074 139.803 1.00 74.16  ? 202 MET B O   1 
ATOM 3045 C CB  . MET B 1 128 ? 102.940 99.904  137.722 1.00 72.39  ? 202 MET B CB  1 
ATOM 3046 C CG  . MET B 1 128 ? 101.867 100.590 136.897 1.00 76.87  ? 202 MET B CG  1 
ATOM 3047 S SD  . MET B 1 128 ? 100.482 99.500  136.513 1.00 89.48  ? 202 MET B SD  1 
ATOM 3048 C CE  . MET B 1 128 ? 99.910  99.083  138.157 1.00 70.33  ? 202 MET B CE  1 
ATOM 3049 N N   . ALA B 1 129 ? 103.979 103.164 137.903 1.00 45.89  ? 203 ALA B N   1 
ATOM 3050 C CA  . ALA B 1 129 ? 103.788 104.495 138.455 1.00 52.13  ? 203 ALA B CA  1 
ATOM 3051 C C   . ALA B 1 129 ? 102.670 105.216 137.718 1.00 59.45  ? 203 ALA B C   1 
ATOM 3052 O O   . ALA B 1 129 ? 102.557 105.121 136.493 1.00 64.21  ? 203 ALA B O   1 
ATOM 3053 C CB  . ALA B 1 129 ? 105.075 105.311 138.379 1.00 59.87  ? 203 ALA B CB  1 
ATOM 3054 N N   . PHE B 1 130 ? 101.850 105.937 138.476 1.00 63.85  ? 204 PHE B N   1 
ATOM 3055 C CA  . PHE B 1 130 ? 100.725 106.690 137.944 1.00 63.08  ? 204 PHE B CA  1 
ATOM 3056 C C   . PHE B 1 130 ? 100.987 108.179 138.117 1.00 66.56  ? 204 PHE B C   1 
ATOM 3057 O O   . PHE B 1 130 ? 101.439 108.613 139.181 1.00 68.03  ? 204 PHE B O   1 
ATOM 3058 C CB  . PHE B 1 130 ? 99.424  106.297 138.644 1.00 65.04  ? 204 PHE B CB  1 
ATOM 3059 C CG  . PHE B 1 130 ? 99.023  104.868 138.424 1.00 63.99  ? 204 PHE B CG  1 
ATOM 3060 C CD1 . PHE B 1 130 ? 99.538  103.857 139.213 1.00 66.78  ? 204 PHE B CD1 1 
ATOM 3061 C CD2 . PHE B 1 130 ? 98.122  104.538 137.428 1.00 67.49  ? 204 PHE B CD2 1 
ATOM 3062 C CE1 . PHE B 1 130 ? 99.164  102.544 139.007 1.00 67.50  ? 204 PHE B CE1 1 
ATOM 3063 C CE2 . PHE B 1 130 ? 97.747  103.229 137.220 1.00 66.63  ? 204 PHE B CE2 1 
ATOM 3064 C CZ  . PHE B 1 130 ? 98.267  102.232 138.008 1.00 64.80  ? 204 PHE B CZ  1 
ATOM 3065 N N   . HIS B 1 131 ? 100.706 108.958 137.070 1.00 86.63  ? 205 HIS B N   1 
ATOM 3066 C CA  . HIS B 1 131 ? 100.897 110.407 137.109 1.00 88.60  ? 205 HIS B CA  1 
ATOM 3067 C C   . HIS B 1 131 ? 99.534  111.071 137.292 1.00 88.81  ? 205 HIS B C   1 
ATOM 3068 O O   . HIS B 1 131 ? 98.736  111.205 136.366 1.00 86.52  ? 205 HIS B O   1 
ATOM 3069 C CB  . HIS B 1 131 ? 101.618 110.900 135.854 1.00 87.62  ? 205 HIS B CB  1 
ATOM 3070 C CG  . HIS B 1 131 ? 100.900 110.602 134.575 1.00 87.80  ? 205 HIS B CG  1 
ATOM 3071 N ND1 . HIS B 1 131 ? 100.881 109.349 134.003 1.00 91.23  ? 205 HIS B ND1 1 
ATOM 3072 C CD2 . HIS B 1 131 ? 100.183 111.402 133.750 1.00 89.67  ? 205 HIS B CD2 1 
ATOM 3073 C CE1 . HIS B 1 131 ? 100.181 109.388 132.884 1.00 90.61  ? 205 HIS B CE1 1 
ATOM 3074 N NE2 . HIS B 1 131 ? 99.745  110.623 132.708 1.00 89.96  ? 205 HIS B NE2 1 
ATOM 3075 N N   . LEU B 1 132 ? 99.269  111.481 138.528 1.00 103.11 ? 206 LEU B N   1 
ATOM 3076 C CA  . LEU B 1 132 ? 98.031  112.177 138.868 1.00 102.74 ? 206 LEU B CA  1 
ATOM 3077 C C   . LEU B 1 132 ? 98.295  113.675 138.791 1.00 104.45 ? 206 LEU B C   1 
ATOM 3078 O O   . LEU B 1 132 ? 98.675  114.304 139.781 1.00 104.01 ? 206 LEU B O   1 
ATOM 3079 C CB  . LEU B 1 132 ? 97.543  111.763 140.251 1.00 102.22 ? 206 LEU B CB  1 
ATOM 3080 C CG  . LEU B 1 132 ? 97.204  110.281 140.436 1.00 100.75 ? 206 LEU B CG  1 
ATOM 3081 C CD1 . LEU B 1 132 ? 98.418  109.485 140.900 1.00 100.49 ? 206 LEU B CD1 1 
ATOM 3082 C CD2 . LEU B 1 132 ? 96.054  110.117 141.407 1.00 100.19 ? 206 LEU B CD2 1 
ATOM 3083 N N   . GLY B 1 133 ? 98.093  114.252 137.610 1.00 110.90 ? 207 GLY B N   1 
ATOM 3084 C CA  . GLY B 1 133 ? 98.400  115.652 137.396 1.00 110.39 ? 207 GLY B CA  1 
ATOM 3085 C C   . GLY B 1 133 ? 99.644  115.852 136.556 1.00 111.78 ? 207 GLY B C   1 
ATOM 3086 O O   . GLY B 1 133 ? 99.607  115.692 135.332 1.00 111.04 ? 207 GLY B O   1 
ATOM 3087 N N   . SER B 1 134 ? 100.751 116.213 137.201 1.00 110.54 ? 208 SER B N   1 
ATOM 3088 C CA  . SER B 1 134 ? 102.008 116.398 136.491 1.00 109.40 ? 208 SER B CA  1 
ATOM 3089 C C   . SER B 1 134 ? 102.495 115.077 135.905 1.00 107.97 ? 208 SER B C   1 
ATOM 3090 O O   . SER B 1 134 ? 102.368 114.013 136.517 1.00 108.28 ? 208 SER B O   1 
ATOM 3091 C CB  . SER B 1 134 ? 103.068 116.979 137.426 1.00 108.64 ? 208 SER B CB  1 
ATOM 3092 O OG  . SER B 1 134 ? 103.297 116.124 138.531 1.00 109.13 ? 208 SER B OG  1 
ATOM 3093 N N   . LEU B 1 135 ? 103.062 115.156 134.705 1.00 98.62  ? 209 LEU B N   1 
ATOM 3094 C CA  . LEU B 1 135 ? 103.540 113.987 133.980 1.00 99.84  ? 209 LEU B CA  1 
ATOM 3095 C C   . LEU B 1 135 ? 105.064 113.980 134.007 1.00 100.74 ? 209 LEU B C   1 
ATOM 3096 O O   . LEU B 1 135 ? 105.700 114.949 133.578 1.00 100.29 ? 209 LEU B O   1 
ATOM 3097 C CB  . LEU B 1 135 ? 103.012 113.991 132.545 1.00 101.36 ? 209 LEU B CB  1 
ATOM 3098 C CG  . LEU B 1 135 ? 103.226 112.771 131.643 1.00 101.44 ? 209 LEU B CG  1 
ATOM 3099 C CD1 . LEU B 1 135 ? 102.098 112.677 130.629 1.00 100.12 ? 209 LEU B CD1 1 
ATOM 3100 C CD2 . LEU B 1 135 ? 104.563 112.837 130.921 1.00 99.60  ? 209 LEU B CD2 1 
ATOM 3101 N N   . GLY B 1 136 ? 105.641 112.893 134.508 1.00 92.56  ? 210 GLY B N   1 
ATOM 3102 C CA  . GLY B 1 136 ? 107.074 112.743 134.610 1.00 90.69  ? 210 GLY B CA  1 
ATOM 3103 C C   . GLY B 1 136 ? 107.638 111.791 133.577 1.00 92.07  ? 210 GLY B C   1 
ATOM 3104 O O   . GLY B 1 136 ? 107.041 111.541 132.523 1.00 93.47  ? 210 GLY B O   1 
ATOM 3105 N N   . PHE B 1 137 ? 108.813 111.248 133.886 1.00 86.18  ? 211 PHE B N   1 
ATOM 3106 C CA  . PHE B 1 137 ? 109.491 110.313 132.999 1.00 83.87  ? 211 PHE B CA  1 
ATOM 3107 C C   . PHE B 1 137 ? 109.368 108.867 133.444 1.00 84.24  ? 211 PHE B C   1 
ATOM 3108 O O   . PHE B 1 137 ? 109.432 107.964 132.603 1.00 86.11  ? 211 PHE B O   1 
ATOM 3109 C CB  . PHE B 1 137 ? 110.974 110.675 132.885 1.00 82.38  ? 211 PHE B CB  1 
ATOM 3110 C CG  . PHE B 1 137 ? 111.231 111.894 132.058 1.00 82.75  ? 211 PHE B CG  1 
ATOM 3111 C CD1 . PHE B 1 137 ? 111.247 111.818 130.678 1.00 84.54  ? 211 PHE B CD1 1 
ATOM 3112 C CD2 . PHE B 1 137 ? 111.436 113.120 132.660 1.00 83.41  ? 211 PHE B CD2 1 
ATOM 3113 C CE1 . PHE B 1 137 ? 111.475 112.941 129.915 1.00 86.63  ? 211 PHE B CE1 1 
ATOM 3114 C CE2 . PHE B 1 137 ? 111.663 114.245 131.903 1.00 84.25  ? 211 PHE B CE2 1 
ATOM 3115 C CZ  . PHE B 1 137 ? 111.684 114.158 130.528 1.00 85.17  ? 211 PHE B CZ  1 
ATOM 3116 N N   . LEU B 1 138 ? 109.195 108.626 134.739 1.00 79.41  ? 212 LEU B N   1 
ATOM 3117 C CA  . LEU B 1 138 ? 109.057 107.283 135.278 1.00 80.77  ? 212 LEU B CA  1 
ATOM 3118 C C   . LEU B 1 138 ? 107.605 106.908 135.546 1.00 86.83  ? 212 LEU B C   1 
ATOM 3119 O O   . LEU B 1 138 ? 107.348 105.864 136.154 1.00 87.66  ? 212 LEU B O   1 
ATOM 3120 C CB  . LEU B 1 138 ? 109.877 107.152 136.561 1.00 82.03  ? 212 LEU B CB  1 
ATOM 3121 C CG  . LEU B 1 138 ? 111.233 107.859 136.569 1.00 82.38  ? 212 LEU B CG  1 
ATOM 3122 C CD1 . LEU B 1 138 ? 111.863 107.796 137.952 1.00 83.75  ? 212 LEU B CD1 1 
ATOM 3123 C CD2 . LEU B 1 138 ? 112.161 107.258 135.528 1.00 83.03  ? 212 LEU B CD2 1 
ATOM 3124 N N   . THR B 1 139 ? 106.652 107.729 135.103 1.00 87.71  ? 213 THR B N   1 
ATOM 3125 C CA  . THR B 1 139 ? 105.232 107.554 135.411 1.00 82.55  ? 213 THR B CA  1 
ATOM 3126 C C   . THR B 1 139 ? 104.442 107.532 134.109 1.00 76.34  ? 213 THR B C   1 
ATOM 3127 O O   . THR B 1 139 ? 103.856 108.545 133.706 1.00 79.24  ? 213 THR B O   1 
ATOM 3128 C CB  . THR B 1 139 ? 104.724 108.668 136.326 1.00 84.77  ? 213 THR B CB  1 
ATOM 3129 O OG1 . THR B 1 139 ? 104.747 109.913 135.617 1.00 86.97  ? 213 THR B OG1 1 
ATOM 3130 C CG2 . THR B 1 139 ? 105.606 108.791 137.554 1.00 81.50  ? 213 THR B CG2 1 
ATOM 3131 N N   . PRO B 1 140 ? 104.406 106.393 133.425 1.00 74.34  ? 214 PRO B N   1 
ATOM 3132 C CA  . PRO B 1 140 ? 103.734 106.341 132.120 1.00 82.56  ? 214 PRO B CA  1 
ATOM 3133 C C   . PRO B 1 140 ? 102.223 106.181 132.201 1.00 85.95  ? 214 PRO B C   1 
ATOM 3134 O O   . PRO B 1 140 ? 101.501 106.672 131.328 1.00 86.65  ? 214 PRO B O   1 
ATOM 3135 C CB  . PRO B 1 140 ? 104.382 105.123 131.453 1.00 82.93  ? 214 PRO B CB  1 
ATOM 3136 C CG  . PRO B 1 140 ? 104.731 104.235 132.595 1.00 83.53  ? 214 PRO B CG  1 
ATOM 3137 C CD  . PRO B 1 140 ? 105.122 105.143 133.730 1.00 78.23  ? 214 PRO B CD  1 
ATOM 3138 N N   . PHE B 1 141 ? 101.730 105.503 133.234 1.00 79.91  ? 215 PHE B N   1 
ATOM 3139 C CA  . PHE B 1 141 ? 100.322 105.133 133.290 1.00 75.57  ? 215 PHE B CA  1 
ATOM 3140 C C   . PHE B 1 141 ? 99.455  106.289 133.771 1.00 75.19  ? 215 PHE B C   1 
ATOM 3141 O O   . PHE B 1 141 ? 99.807  107.003 134.714 1.00 78.63  ? 215 PHE B O   1 
ATOM 3142 C CB  . PHE B 1 141 ? 100.124 103.926 134.204 1.00 74.64  ? 215 PHE B CB  1 
ATOM 3143 C CG  . PHE B 1 141 ? 100.624 102.639 133.623 1.00 71.95  ? 215 PHE B CG  1 
ATOM 3144 C CD1 . PHE B 1 141 ? 101.932 102.241 133.813 1.00 71.75  ? 215 PHE B CD1 1 
ATOM 3145 C CD2 . PHE B 1 141 ? 99.782  101.827 132.886 1.00 77.57  ? 215 PHE B CD2 1 
ATOM 3146 C CE1 . PHE B 1 141 ? 102.392 101.056 133.283 1.00 75.38  ? 215 PHE B CE1 1 
ATOM 3147 C CE2 . PHE B 1 141 ? 100.236 100.641 132.351 1.00 79.01  ? 215 PHE B CE2 1 
ATOM 3148 C CZ  . PHE B 1 141 ? 101.544 100.256 132.549 1.00 80.18  ? 215 PHE B CZ  1 
ATOM 3149 N N   . SER B 1 142 ? 98.311  106.461 133.117 1.00 77.85  ? 216 SER B N   1 
ATOM 3150 C CA  . SER B 1 142 ? 97.328  107.460 133.504 1.00 82.19  ? 216 SER B CA  1 
ATOM 3151 C C   . SER B 1 142 ? 96.299  106.845 134.445 1.00 85.15  ? 216 SER B C   1 
ATOM 3152 O O   . SER B 1 142 ? 96.002  105.650 134.376 1.00 85.95  ? 216 SER B O   1 
ATOM 3153 C CB  . SER B 1 142 ? 96.631  108.041 132.273 1.00 85.83  ? 216 SER B CB  1 
ATOM 3154 O OG  . SER B 1 142 ? 95.768  109.106 132.631 1.00 88.64  ? 216 SER B OG  1 
ATOM 3155 N N   . PHE B 1 143 ? 95.754  107.679 135.331 1.00 95.72  ? 217 PHE B N   1 
ATOM 3156 C CA  . PHE B 1 143 ? 94.857  107.180 136.364 1.00 95.17  ? 217 PHE B CA  1 
ATOM 3157 C C   . PHE B 1 143 ? 93.460  106.866 135.846 1.00 97.51  ? 217 PHE B C   1 
ATOM 3158 O O   . PHE B 1 143 ? 92.724  106.126 136.507 1.00 98.96  ? 217 PHE B O   1 
ATOM 3159 C CB  . PHE B 1 143 ? 94.764  108.182 137.515 1.00 96.46  ? 217 PHE B CB  1 
ATOM 3160 C CG  . PHE B 1 143 ? 94.145  107.613 138.759 1.00 98.09  ? 217 PHE B CG  1 
ATOM 3161 C CD1 . PHE B 1 143 ? 94.867  106.764 139.579 1.00 95.78  ? 217 PHE B CD1 1 
ATOM 3162 C CD2 . PHE B 1 143 ? 92.840  107.920 139.104 1.00 97.76  ? 217 PHE B CD2 1 
ATOM 3163 C CE1 . PHE B 1 143 ? 94.303  106.234 140.720 1.00 96.15  ? 217 PHE B CE1 1 
ATOM 3164 C CE2 . PHE B 1 143 ? 92.269  107.393 140.247 1.00 96.83  ? 217 PHE B CE2 1 
ATOM 3165 C CZ  . PHE B 1 143 ? 93.003  106.548 141.055 1.00 96.71  ? 217 PHE B CZ  1 
ATOM 3166 N N   . GLU B 1 144 ? 93.075  107.401 134.691 1.00 103.17 ? 218 GLU B N   1 
ATOM 3167 C CA  . GLU B 1 144 ? 91.760  107.104 134.142 1.00 102.48 ? 218 GLU B CA  1 
ATOM 3168 C C   . GLU B 1 144 ? 91.670  105.634 133.750 1.00 102.11 ? 218 GLU B C   1 
ATOM 3169 O O   . GLU B 1 144 ? 92.614  105.064 133.194 1.00 102.48 ? 218 GLU B O   1 
ATOM 3170 C CB  . GLU B 1 144 ? 91.470  108.000 132.937 1.00 102.52 ? 218 GLU B CB  1 
ATOM 3171 C CG  . GLU B 1 144 ? 92.578  108.045 131.893 1.00 103.80 ? 218 GLU B CG  1 
ATOM 3172 C CD  . GLU B 1 144 ? 92.438  106.966 130.837 1.00 104.46 ? 218 GLU B CD  1 
ATOM 3173 O OE1 . GLU B 1 144 ? 91.349  106.361 130.743 1.00 104.52 ? 218 GLU B OE1 1 
ATOM 3174 O OE2 . GLU B 1 144 ? 93.417  106.723 130.101 1.00 101.73 ? 218 GLU B OE2 1 
ATOM 3175 N N   . ASN B 1 145 ? 90.523  105.022 134.049 1.00 95.78  ? 219 ASN B N   1 
ATOM 3176 C CA  . ASN B 1 145 ? 90.306  103.593 133.819 1.00 95.88  ? 219 ASN B CA  1 
ATOM 3177 C C   . ASN B 1 145 ? 91.415  102.764 134.459 1.00 94.81  ? 219 ASN B C   1 
ATOM 3178 O O   . ASN B 1 145 ? 91.965  101.842 133.852 1.00 94.54  ? 219 ASN B O   1 
ATOM 3179 C CB  . ASN B 1 145 ? 90.181  103.285 132.325 1.00 96.46  ? 219 ASN B CB  1 
ATOM 3180 C CG  . ASN B 1 145 ? 89.576  101.919 132.061 1.00 97.31  ? 219 ASN B CG  1 
ATOM 3181 O OD1 . ASN B 1 145 ? 88.989  101.304 132.951 1.00 96.69  ? 219 ASN B OD1 1 
ATOM 3182 N ND2 . ASN B 1 145 ? 89.717  101.437 130.832 1.00 97.40  ? 219 ASN B ND2 1 
ATOM 3183 N N   . PHE B 1 146 ? 91.752  103.104 135.704 1.00 93.89  ? 220 PHE B N   1 
ATOM 3184 C CA  . PHE B 1 146 ? 92.852  102.432 136.385 1.00 94.53  ? 220 PHE B CA  1 
ATOM 3185 C C   . PHE B 1 146 ? 92.574  100.950 136.591 1.00 95.73  ? 220 PHE B C   1 
ATOM 3186 O O   . PHE B 1 146 ? 93.494  100.132 136.487 1.00 97.11  ? 220 PHE B O   1 
ATOM 3187 C CB  . PHE B 1 146 ? 93.139  103.111 137.725 1.00 95.13  ? 220 PHE B CB  1 
ATOM 3188 C CG  . PHE B 1 146 ? 92.087  102.870 138.768 1.00 95.75  ? 220 PHE B CG  1 
ATOM 3189 C CD1 . PHE B 1 146 ? 90.918  103.612 138.778 1.00 97.03  ? 220 PHE B CD1 1 
ATOM 3190 C CD2 . PHE B 1 146 ? 92.267  101.903 139.742 1.00 96.10  ? 220 PHE B CD2 1 
ATOM 3191 C CE1 . PHE B 1 146 ? 89.949  103.393 139.738 1.00 98.27  ? 220 PHE B CE1 1 
ATOM 3192 C CE2 . PHE B 1 146 ? 91.302  101.678 140.703 1.00 97.26  ? 220 PHE B CE2 1 
ATOM 3193 C CZ  . PHE B 1 146 ? 90.142  102.424 140.702 1.00 97.81  ? 220 PHE B CZ  1 
ATOM 3194 N N   . GLN B 1 147 ? 91.321  100.584 136.875 1.00 99.21  ? 221 GLN B N   1 
ATOM 3195 C CA  . GLN B 1 147 ? 91.012  99.192  137.185 1.00 98.39  ? 221 GLN B CA  1 
ATOM 3196 C C   . GLN B 1 147 ? 91.328  98.278  136.009 1.00 97.36  ? 221 GLN B C   1 
ATOM 3197 O O   . GLN B 1 147 ? 91.894  97.194  136.192 1.00 99.21  ? 221 GLN B O   1 
ATOM 3198 C CB  . GLN B 1 147 ? 89.545  99.056  137.589 1.00 96.03  ? 221 GLN B CB  1 
ATOM 3199 C CG  . GLN B 1 147 ? 89.215  97.731  138.254 1.00 94.91  ? 221 GLN B CG  1 
ATOM 3200 C CD  . GLN B 1 147 ? 89.823  97.618  139.636 1.00 97.89  ? 221 GLN B CD  1 
ATOM 3201 O OE1 . GLN B 1 147 ? 90.189  98.623  140.245 1.00 98.60  ? 221 GLN B OE1 1 
ATOM 3202 N NE2 . GLN B 1 147 ? 89.937  96.394  140.139 1.00 98.57  ? 221 GLN B NE2 1 
ATOM 3203 N N   . SER B 1 148 ? 90.970  98.695  134.794 1.00 96.81  ? 222 SER B N   1 
ATOM 3204 C CA  . SER B 1 148 ? 91.289  97.891  133.620 1.00 98.35  ? 222 SER B CA  1 
ATOM 3205 C C   . SER B 1 148 ? 92.795  97.773  133.429 1.00 98.49  ? 222 SER B C   1 
ATOM 3206 O O   . SER B 1 148 ? 93.300  96.706  133.060 1.00 98.75  ? 222 SER B O   1 
ATOM 3207 C CB  . SER B 1 148 ? 90.632  98.491  132.378 1.00 97.07  ? 222 SER B CB  1 
ATOM 3208 O OG  . SER B 1 148 ? 90.946  97.735  131.221 1.00 96.47  ? 222 SER B OG  1 
ATOM 3209 N N   . GLN B 1 149 ? 93.527  98.861  133.676 1.00 91.16  ? 223 GLN B N   1 
ATOM 3210 C CA  . GLN B 1 149 ? 94.977  98.836  133.522 1.00 89.40  ? 223 GLN B CA  1 
ATOM 3211 C C   . GLN B 1 149 ? 95.629  97.921  134.551 1.00 90.97  ? 223 GLN B C   1 
ATOM 3212 O O   . GLN B 1 149 ? 96.592  97.212  134.236 1.00 92.16  ? 223 GLN B O   1 
ATOM 3213 C CB  . GLN B 1 149 ? 95.531  100.255 133.631 1.00 86.43  ? 223 GLN B CB  1 
ATOM 3214 C CG  . GLN B 1 149 ? 94.952  101.214 132.609 1.00 83.93  ? 223 GLN B CG  1 
ATOM 3215 C CD  . GLN B 1 149 ? 95.514  102.613 132.741 1.00 89.29  ? 223 GLN B CD  1 
ATOM 3216 O OE1 . GLN B 1 149 ? 96.425  102.855 133.531 1.00 93.10  ? 223 GLN B OE1 1 
ATOM 3217 N NE2 . GLN B 1 149 ? 94.967  103.545 131.971 1.00 90.24  ? 223 GLN B NE2 1 
ATOM 3218 N N   . VAL B 1 150 ? 95.124  97.924  135.786 1.00 84.87  ? 224 VAL B N   1 
ATOM 3219 C CA  . VAL B 1 150 ? 95.708  97.083  136.828 1.00 85.97  ? 224 VAL B CA  1 
ATOM 3220 C C   . VAL B 1 150 ? 95.476  95.610  136.521 1.00 82.57  ? 224 VAL B C   1 
ATOM 3221 O O   . VAL B 1 150 ? 96.341  94.765  136.780 1.00 85.10  ? 224 VAL B O   1 
ATOM 3222 C CB  . VAL B 1 150 ? 95.147  97.473  138.208 1.00 90.29  ? 224 VAL B CB  1 
ATOM 3223 C CG1 . VAL B 1 150 ? 95.674  96.535  139.281 1.00 89.98  ? 224 VAL B CG1 1 
ATOM 3224 C CG2 . VAL B 1 150 ? 95.518  98.906  138.543 1.00 91.27  ? 224 VAL B CG2 1 
ATOM 3225 N N   . THR B 1 151 ? 94.312  95.276  135.961 1.00 85.48  ? 225 THR B N   1 
ATOM 3226 C CA  . THR B 1 151 ? 94.029  93.885  135.626 1.00 90.45  ? 225 THR B CA  1 
ATOM 3227 C C   . THR B 1 151 ? 94.988  93.364  134.564 1.00 92.98  ? 225 THR B C   1 
ATOM 3228 O O   . THR B 1 151 ? 95.396  92.197  134.604 1.00 93.73  ? 225 THR B O   1 
ATOM 3229 C CB  . THR B 1 151 ? 92.582  93.738  135.156 1.00 93.77  ? 225 THR B CB  1 
ATOM 3230 O OG1 . THR B 1 151 ? 92.334  94.648  134.076 1.00 91.78  ? 225 THR B OG1 1 
ATOM 3231 C CG2 . THR B 1 151 ? 91.616  94.022  136.297 1.00 94.41  ? 225 THR B CG2 1 
ATOM 3232 N N   . GLN B 1 152 ? 95.354  94.212  133.600 1.00 98.08  ? 226 GLN B N   1 
ATOM 3233 C CA  . GLN B 1 152 ? 96.258  93.779  132.539 1.00 96.97  ? 226 GLN B CA  1 
ATOM 3234 C C   . GLN B 1 152 ? 97.637  93.430  133.090 1.00 98.18  ? 226 GLN B C   1 
ATOM 3235 O O   . GLN B 1 152 ? 98.237  92.427  132.688 1.00 99.77  ? 226 GLN B O   1 
ATOM 3236 C CB  . GLN B 1 152 ? 96.364  94.865  131.468 1.00 94.02  ? 226 GLN B CB  1 
ATOM 3237 C CG  . GLN B 1 152 ? 97.476  94.639  130.456 1.00 96.62  ? 226 GLN B CG  1 
ATOM 3238 C CD  . GLN B 1 152 ? 97.289  93.363  129.658 1.00 99.68  ? 226 GLN B CD  1 
ATOM 3239 O OE1 . GLN B 1 152 ? 96.167  92.988  129.318 1.00 99.14  ? 226 GLN B OE1 1 
ATOM 3240 N NE2 . GLN B 1 152 ? 98.392  92.688  129.356 1.00 99.81  ? 226 GLN B NE2 1 
ATOM 3241 N N   . VAL B 1 153 ? 98.156  94.246  134.009 1.00 83.85  ? 227 VAL B N   1 
ATOM 3242 C CA  . VAL B 1 153 ? 99.483  93.994  134.565 1.00 77.43  ? 227 VAL B CA  1 
ATOM 3243 C C   . VAL B 1 153 ? 99.491  92.704  135.375 1.00 78.44  ? 227 VAL B C   1 
ATOM 3244 O O   . VAL B 1 153 ? 100.414 91.889  135.267 1.00 75.67  ? 227 VAL B O   1 
ATOM 3245 C CB  . VAL B 1 153 ? 99.944  95.192  135.411 1.00 76.18  ? 227 VAL B CB  1 
ATOM 3246 C CG1 . VAL B 1 153 ? 101.259 94.876  136.091 1.00 78.05  ? 227 VAL B CG1 1 
ATOM 3247 C CG2 . VAL B 1 153 ? 100.071 96.430  134.544 1.00 81.91  ? 227 VAL B CG2 1 
ATOM 3248 N N   . ILE B 1 154 ? 98.468  92.505  136.207 1.00 95.90  ? 228 ILE B N   1 
ATOM 3249 C CA  . ILE B 1 154 ? 98.409  91.308  137.040 1.00 94.29  ? 228 ILE B CA  1 
ATOM 3250 C C   . ILE B 1 154 ? 98.232  90.063  136.180 1.00 93.63  ? 228 ILE B C   1 
ATOM 3251 O O   . ILE B 1 154 ? 98.954  89.072  136.339 1.00 95.88  ? 228 ILE B O   1 
ATOM 3252 C CB  . ILE B 1 154 ? 97.284  91.438  138.081 1.00 93.18  ? 228 ILE B CB  1 
ATOM 3253 C CG1 . ILE B 1 154 ? 97.477  92.699  138.925 1.00 91.14  ? 228 ILE B CG1 1 
ATOM 3254 C CG2 . ILE B 1 154 ? 97.212  90.195  138.953 1.00 94.55  ? 228 ILE B CG2 1 
ATOM 3255 C CD1 . ILE B 1 154 ? 96.366  92.942  139.916 1.00 92.11  ? 228 ILE B CD1 1 
ATOM 3256 N N   . GLU B 1 155 ? 97.272  90.093  135.257 1.00 100.80 ? 229 GLU B N   1 
ATOM 3257 C CA  . GLU B 1 155 ? 96.966  88.903  134.469 1.00 102.90 ? 229 GLU B CA  1 
ATOM 3258 C C   . GLU B 1 155 ? 97.897  88.770  133.269 1.00 105.83 ? 229 GLU B C   1 
ATOM 3259 O O   . GLU B 1 155 ? 98.640  87.790  133.151 1.00 106.61 ? 229 GLU B O   1 
ATOM 3260 C CB  . GLU B 1 155 ? 95.502  88.936  134.019 1.00 103.41 ? 229 GLU B CB  1 
ATOM 3261 C CG  . GLU B 1 155 ? 94.505  88.900  135.166 1.00 105.74 ? 229 GLU B CG  1 
ATOM 3262 C CD  . GLU B 1 155 ? 93.066  88.916  134.689 1.00 106.81 ? 229 GLU B CD  1 
ATOM 3263 O OE1 . GLU B 1 155 ? 92.843  89.119  133.477 1.00 105.75 ? 229 GLU B OE1 1 
ATOM 3264 O OE2 . GLU B 1 155 ? 92.158  88.728  135.526 1.00 107.00 ? 229 GLU B OE2 1 
ATOM 3265 N N   . GLY B 1 156 ? 97.870  89.749  132.370 1.00 109.30 ? 230 GLY B N   1 
ATOM 3266 C CA  . GLY B 1 156 ? 98.651  89.691  131.155 1.00 108.23 ? 230 GLY B CA  1 
ATOM 3267 C C   . GLY B 1 156 ? 100.076 90.172  131.355 1.00 108.98 ? 230 GLY B C   1 
ATOM 3268 O O   . GLY B 1 156 ? 100.532 90.446  132.466 1.00 110.00 ? 230 GLY B O   1 
ATOM 3269 N N   . ASN B 1 157 ? 100.788 90.272  130.238 1.00 113.08 ? 231 ASN B N   1 
ATOM 3270 C CA  . ASN B 1 157 ? 102.174 90.718  130.216 1.00 115.36 ? 231 ASN B CA  1 
ATOM 3271 C C   . ASN B 1 157 ? 102.237 92.137  129.671 1.00 113.43 ? 231 ASN B C   1 
ATOM 3272 O O   . ASN B 1 157 ? 101.510 92.479  128.733 1.00 111.75 ? 231 ASN B O   1 
ATOM 3273 C CB  . ASN B 1 157 ? 103.037 89.783  129.365 1.00 115.44 ? 231 ASN B CB  1 
ATOM 3274 C CG  . ASN B 1 157 ? 103.103 88.377  129.928 1.00 116.60 ? 231 ASN B CG  1 
ATOM 3275 O OD1 . ASN B 1 157 ? 102.260 87.976  130.730 1.00 116.98 ? 231 ASN B OD1 1 
ATOM 3276 N ND2 . ASN B 1 157 ? 104.109 87.618  129.507 1.00 115.84 ? 231 ASN B ND2 1 
ATOM 3277 N N   . ALA B 1 158 ? 103.099 92.958  130.264 1.00 104.51 ? 232 ALA B N   1 
ATOM 3278 C CA  . ALA B 1 158 ? 103.312 94.327  129.825 1.00 104.35 ? 232 ALA B CA  1 
ATOM 3279 C C   . ALA B 1 158 ? 104.801 94.585  129.639 1.00 106.57 ? 232 ALA B C   1 
ATOM 3280 O O   . ALA B 1 158 ? 105.635 94.066  130.386 1.00 107.91 ? 232 ALA B O   1 
ATOM 3281 C CB  . ALA B 1 158 ? 102.726 95.328  130.824 1.00 101.83 ? 232 ALA B CB  1 
ATOM 3282 N N   . ALA B 1 159 ? 105.126 95.391  128.632 1.00 98.88  ? 233 ALA B N   1 
ATOM 3283 C CA  . ALA B 1 159 ? 106.517 95.705  128.339 1.00 93.06  ? 233 ALA B CA  1 
ATOM 3284 C C   . ALA B 1 159 ? 107.136 96.516  129.471 1.00 95.44  ? 233 ALA B C   1 
ATOM 3285 O O   . ALA B 1 159 ? 106.467 97.316  130.131 1.00 97.83  ? 233 ALA B O   1 
ATOM 3286 C CB  . ALA B 1 159 ? 106.624 96.473  127.023 1.00 90.96  ? 233 ALA B CB  1 
ATOM 3287 N N   . VAL B 1 160 ? 108.434 96.303  129.692 1.00 81.21  ? 234 VAL B N   1 
ATOM 3288 C CA  . VAL B 1 160 ? 109.153 96.934  130.790 1.00 81.83  ? 234 VAL B CA  1 
ATOM 3289 C C   . VAL B 1 160 ? 110.452 97.536  130.274 1.00 80.53  ? 234 VAL B C   1 
ATOM 3290 O O   . VAL B 1 160 ? 110.945 97.191  129.198 1.00 78.97  ? 234 VAL B O   1 
ATOM 3291 C CB  . VAL B 1 160 ? 109.448 95.945  131.937 1.00 78.51  ? 234 VAL B CB  1 
ATOM 3292 C CG1 . VAL B 1 160 ? 108.155 95.461  132.573 1.00 80.75  ? 234 VAL B CG1 1 
ATOM 3293 C CG2 . VAL B 1 160 ? 110.267 94.775  131.425 1.00 76.24  ? 234 VAL B CG2 1 
ATOM 3294 N N   . VAL B 1 161 ? 111.000 98.455  131.064 1.00 75.89  ? 235 VAL B N   1 
ATOM 3295 C CA  . VAL B 1 161 ? 112.321 99.030  130.834 1.00 72.83  ? 235 VAL B CA  1 
ATOM 3296 C C   . VAL B 1 161 ? 113.200 98.645  132.014 1.00 72.56  ? 235 VAL B C   1 
ATOM 3297 O O   . VAL B 1 161 ? 112.899 99.003  133.160 1.00 74.03  ? 235 VAL B O   1 
ATOM 3298 C CB  . VAL B 1 161 ? 112.269 100.557 130.677 1.00 70.85  ? 235 VAL B CB  1 
ATOM 3299 C CG1 . VAL B 1 161 ? 113.675 101.134 130.664 1.00 70.00  ? 235 VAL B CG1 1 
ATOM 3300 C CG2 . VAL B 1 161 ? 111.536 100.935 129.416 1.00 71.16  ? 235 VAL B CG2 1 
ATOM 3301 N N   . LEU B 1 162 ? 114.282 97.919  131.739 1.00 59.00  ? 236 LEU B N   1 
ATOM 3302 C CA  . LEU B 1 162 ? 115.233 97.533  132.780 1.00 55.75  ? 236 LEU B CA  1 
ATOM 3303 C C   . LEU B 1 162 ? 116.189 98.699  133.006 1.00 58.37  ? 236 LEU B C   1 
ATOM 3304 O O   . LEU B 1 162 ? 117.310 98.745  132.493 1.00 60.96  ? 236 LEU B O   1 
ATOM 3305 C CB  . LEU B 1 162 ? 115.969 96.257  132.399 1.00 59.44  ? 236 LEU B CB  1 
ATOM 3306 C CG  . LEU B 1 162 ? 115.105 95.004  132.264 1.00 60.51  ? 236 LEU B CG  1 
ATOM 3307 C CD1 . LEU B 1 162 ? 115.964 93.800  131.922 1.00 58.08  ? 236 LEU B CD1 1 
ATOM 3308 C CD2 . LEU B 1 162 ? 114.325 94.762  133.542 1.00 59.47  ? 236 LEU B CD2 1 
ATOM 3309 N N   . ARG B 1 163 ? 115.723 99.663  133.793 1.00 58.81  ? 237 ARG B N   1 
ATOM 3310 C CA  . ARG B 1 163 ? 116.495 100.869 134.052 1.00 62.64  ? 237 ARG B CA  1 
ATOM 3311 C C   . ARG B 1 163 ? 117.746 100.541 134.856 1.00 63.94  ? 237 ARG B C   1 
ATOM 3312 O O   . ARG B 1 163 ? 117.699 99.754  135.805 1.00 67.56  ? 237 ARG B O   1 
ATOM 3313 C CB  . ARG B 1 163 ? 115.639 101.888 134.796 1.00 65.33  ? 237 ARG B CB  1 
ATOM 3314 C CG  . ARG B 1 163 ? 114.318 102.184 134.117 1.00 66.40  ? 237 ARG B CG  1 
ATOM 3315 C CD  . ARG B 1 163 ? 113.561 103.285 134.830 1.00 64.48  ? 237 ARG B CD  1 
ATOM 3316 N NE  . ARG B 1 163 ? 113.508 104.505 134.035 1.00 62.96  ? 237 ARG B NE  1 
ATOM 3317 C CZ  . ARG B 1 163 ? 112.585 104.760 133.119 1.00 62.84  ? 237 ARG B CZ  1 
ATOM 3318 N NH1 . ARG B 1 163 ? 111.619 103.896 132.852 1.00 67.64  ? 237 ARG B NH1 1 
ATOM 3319 N NH2 . ARG B 1 163 ? 112.632 105.909 132.453 1.00 65.28  ? 237 ARG B NH2 1 
ATOM 3320 N N   . SER B 1 164 ? 118.862 101.155 134.479 1.00 50.97  ? 238 SER B N   1 
ATOM 3321 C CA  . SER B 1 164 ? 120.129 100.888 135.138 1.00 49.02  ? 238 SER B CA  1 
ATOM 3322 C C   . SER B 1 164 ? 120.240 101.675 136.436 1.00 55.37  ? 238 SER B C   1 
ATOM 3323 O O   . SER B 1 164 ? 119.640 102.741 136.597 1.00 65.42  ? 238 SER B O   1 
ATOM 3324 C CB  . SER B 1 164 ? 121.295 101.240 134.216 1.00 56.78  ? 238 SER B CB  1 
ATOM 3325 O OG  . SER B 1 164 ? 121.216 100.521 132.998 1.00 60.81  ? 238 SER B OG  1 
ATOM 3326 N N   . ARG B 1 165 ? 121.022 101.136 137.368 1.00 49.25  ? 239 ARG B N   1 
ATOM 3327 C CA  . ARG B 1 165 ? 121.301 101.796 138.633 1.00 40.96  ? 239 ARG B CA  1 
ATOM 3328 C C   . ARG B 1 165 ? 122.789 101.706 138.937 1.00 48.04  ? 239 ARG B C   1 
ATOM 3329 O O   . ARG B 1 165 ? 123.497 100.831 138.433 1.00 55.08  ? 239 ARG B O   1 
ATOM 3330 C CB  . ARG B 1 165 ? 120.492 101.189 139.786 1.00 43.58  ? 239 ARG B CB  1 
ATOM 3331 C CG  . ARG B 1 165 ? 118.994 101.378 139.657 1.00 52.40  ? 239 ARG B CG  1 
ATOM 3332 C CD  . ARG B 1 165 ? 118.297 101.156 140.984 1.00 48.10  ? 239 ARG B CD  1 
ATOM 3333 N NE  . ARG B 1 165 ? 118.458 99.790  141.463 1.00 44.68  ? 239 ARG B NE  1 
ATOM 3334 C CZ  . ARG B 1 165 ? 117.966 99.338  142.608 1.00 55.25  ? 239 ARG B CZ  1 
ATOM 3335 N NH1 . ARG B 1 165 ? 117.277 100.122 143.421 1.00 59.08  ? 239 ARG B NH1 1 
ATOM 3336 N NH2 . ARG B 1 165 ? 118.170 98.069  142.945 1.00 57.81  ? 239 ARG B NH2 1 
ATOM 3337 N N   . LEU B 1 166 ? 123.258 102.630 139.770 1.00 54.99  ? 240 LEU B N   1 
ATOM 3338 C CA  . LEU B 1 166 ? 124.659 102.719 140.155 1.00 56.08  ? 240 LEU B CA  1 
ATOM 3339 C C   . LEU B 1 166 ? 124.827 102.292 141.605 1.00 56.18  ? 240 LEU B C   1 
ATOM 3340 O O   . LEU B 1 166 ? 124.135 102.806 142.490 1.00 57.28  ? 240 LEU B O   1 
ATOM 3341 C CB  . LEU B 1 166 ? 125.188 104.143 139.981 1.00 48.78  ? 240 LEU B CB  1 
ATOM 3342 C CG  . LEU B 1 166 ? 125.095 104.782 138.600 1.00 50.26  ? 240 LEU B CG  1 
ATOM 3343 C CD1 . LEU B 1 166 ? 125.550 106.225 138.650 1.00 53.67  ? 240 LEU B CD1 1 
ATOM 3344 C CD2 . LEU B 1 166 ? 125.909 103.996 137.586 1.00 52.62  ? 240 LEU B CD2 1 
ATOM 3345 N N   . LYS B 1 167 ? 125.748 101.366 141.848 1.00 52.96  ? 241 LYS B N   1 
ATOM 3346 C CA  . LYS B 1 167 ? 126.159 101.041 143.206 1.00 45.50  ? 241 LYS B CA  1 
ATOM 3347 C C   . LYS B 1 167 ? 127.326 101.948 143.576 1.00 50.59  ? 241 LYS B C   1 
ATOM 3348 O O   . LYS B 1 167 ? 128.292 102.074 142.815 1.00 60.13  ? 241 LYS B O   1 
ATOM 3349 C CB  . LYS B 1 167 ? 126.528 99.563  143.343 1.00 48.25  ? 241 LYS B CB  1 
ATOM 3350 C CG  . LYS B 1 167 ? 127.746 99.120  142.562 1.00 53.63  ? 241 LYS B CG  1 
ATOM 3351 C CD  . LYS B 1 167 ? 127.982 97.629  142.711 1.00 55.38  ? 241 LYS B CD  1 
ATOM 3352 C CE  . LYS B 1 167 ? 128.483 97.297  144.106 1.00 61.10  ? 241 LYS B CE  1 
ATOM 3353 N NZ  . LYS B 1 167 ? 128.824 95.856  144.251 1.00 60.41  ? 241 LYS B NZ  1 
ATOM 3354 N N   . VAL B 1 168 ? 127.218 102.605 144.724 1.00 43.97  ? 242 VAL B N   1 
ATOM 3355 C CA  . VAL B 1 168 ? 128.145 103.654 145.124 1.00 47.98  ? 242 VAL B CA  1 
ATOM 3356 C C   . VAL B 1 168 ? 128.714 103.299 146.487 1.00 54.61  ? 242 VAL B C   1 
ATOM 3357 O O   . VAL B 1 168 ? 127.959 103.080 147.442 1.00 55.27  ? 242 VAL B O   1 
ATOM 3358 C CB  . VAL B 1 168 ? 127.458 105.025 145.160 1.00 48.21  ? 242 VAL B CB  1 
ATOM 3359 C CG1 . VAL B 1 168 ? 128.399 106.058 145.702 1.00 51.11  ? 242 VAL B CG1 1 
ATOM 3360 C CG2 . VAL B 1 168 ? 126.981 105.415 143.770 1.00 55.19  ? 242 VAL B CG2 1 
ATOM 3361 N N   . ARG B 1 169 ? 130.039 103.256 146.582 1.00 55.50  ? 243 ARG B N   1 
ATOM 3362 C CA  . ARG B 1 169 ? 130.736 102.991 147.831 1.00 46.69  ? 243 ARG B CA  1 
ATOM 3363 C C   . ARG B 1 169 ? 131.508 104.231 148.251 1.00 51.45  ? 243 ARG B C   1 
ATOM 3364 O O   . ARG B 1 169 ? 132.288 104.776 147.463 1.00 59.90  ? 243 ARG B O   1 
ATOM 3365 C CB  . ARG B 1 169 ? 131.692 101.807 147.686 1.00 55.45  ? 243 ARG B CB  1 
ATOM 3366 C CG  . ARG B 1 169 ? 131.014 100.456 147.619 1.00 60.16  ? 243 ARG B CG  1 
ATOM 3367 C CD  . ARG B 1 169 ? 132.033 99.356  147.385 1.00 57.16  ? 243 ARG B CD  1 
ATOM 3368 N NE  . ARG B 1 169 ? 133.247 99.567  148.164 1.00 61.30  ? 243 ARG B NE  1 
ATOM 3369 C CZ  . ARG B 1 169 ? 133.421 99.148  149.410 1.00 62.10  ? 243 ARG B CZ  1 
ATOM 3370 N NH1 . ARG B 1 169 ? 132.475 98.484  150.053 1.00 59.92  ? 243 ARG B NH1 1 
ATOM 3371 N NH2 . ARG B 1 169 ? 134.572 99.402  150.025 1.00 61.85  ? 243 ARG B NH2 1 
ATOM 3372 N N   . VAL B 1 170 ? 131.295 104.671 149.486 1.00 46.41  ? 244 VAL B N   1 
ATOM 3373 C CA  . VAL B 1 170 ? 132.028 105.789 150.067 1.00 39.74  ? 244 VAL B CA  1 
ATOM 3374 C C   . VAL B 1 170 ? 132.925 105.231 151.160 1.00 47.17  ? 244 VAL B C   1 
ATOM 3375 O O   . VAL B 1 170 ? 132.436 104.684 152.156 1.00 57.61  ? 244 VAL B O   1 
ATOM 3376 C CB  . VAL B 1 170 ? 131.085 106.866 150.621 1.00 43.43  ? 244 VAL B CB  1 
ATOM 3377 C CG1 . VAL B 1 170 ? 131.882 108.035 151.163 1.00 48.93  ? 244 VAL B CG1 1 
ATOM 3378 C CG2 . VAL B 1 170 ? 130.122 107.331 149.543 1.00 49.94  ? 244 VAL B CG2 1 
ATOM 3379 N N   . VAL B 1 171 ? 134.234 105.366 150.975 1.00 56.99  ? 245 VAL B N   1 
ATOM 3380 C CA  . VAL B 1 171 ? 135.228 104.828 151.895 1.00 61.18  ? 245 VAL B CA  1 
ATOM 3381 C C   . VAL B 1 171 ? 135.915 105.991 152.592 1.00 65.90  ? 245 VAL B C   1 
ATOM 3382 O O   . VAL B 1 171 ? 136.438 106.898 151.933 1.00 65.18  ? 245 VAL B O   1 
ATOM 3383 C CB  . VAL B 1 171 ? 136.251 103.942 151.164 1.00 59.16  ? 245 VAL B CB  1 
ATOM 3384 C CG1 . VAL B 1 171 ? 137.241 103.351 152.155 1.00 59.85  ? 245 VAL B CG1 1 
ATOM 3385 C CG2 . VAL B 1 171 ? 135.540 102.843 150.395 1.00 56.64  ? 245 VAL B CG2 1 
ATOM 3386 N N   . LYS B 1 172 ? 135.915 105.963 153.920 1.00 64.18  ? 246 LYS B N   1 
ATOM 3387 C CA  . LYS B 1 172 ? 136.507 107.031 154.713 1.00 52.64  ? 246 LYS B CA  1 
ATOM 3388 C C   . LYS B 1 172 ? 137.994 106.785 154.941 1.00 57.75  ? 246 LYS B C   1 
ATOM 3389 O O   . LYS B 1 172 ? 138.450 105.641 154.939 1.00 62.02  ? 246 LYS B O   1 
ATOM 3390 C CB  . LYS B 1 172 ? 135.783 107.162 156.051 1.00 53.13  ? 246 LYS B CB  1 
ATOM 3391 C CG  . LYS B 1 172 ? 134.341 107.615 155.927 1.00 57.18  ? 246 LYS B CG  1 
ATOM 3392 C CD  . LYS B 1 172 ? 134.251 109.005 155.331 1.00 54.13  ? 246 LYS B CD  1 
ATOM 3393 C CE  . LYS B 1 172 ? 132.811 109.479 155.263 1.00 57.12  ? 246 LYS B CE  1 
ATOM 3394 N NZ  . LYS B 1 172 ? 132.712 110.886 154.786 1.00 62.06  ? 246 LYS B NZ  1 
ATOM 3395 N N   . ALA B 1 203 ? 132.420 101.490 154.606 1.00 84.17  ? 277 ALA B N   1 
ATOM 3396 C CA  . ALA B 1 203 ? 131.955 100.832 153.392 1.00 86.92  ? 277 ALA B CA  1 
ATOM 3397 C C   . ALA B 1 203 ? 130.437 100.910 153.277 1.00 85.62  ? 277 ALA B C   1 
ATOM 3398 O O   . ALA B 1 203 ? 129.764 99.891  153.123 1.00 83.58  ? 277 ALA B O   1 
ATOM 3399 C CB  . ALA B 1 203 ? 132.416 99.383  153.365 1.00 81.46  ? 277 ALA B CB  1 
ATOM 3400 N N   . MET B 1 204 ? 129.904 102.127 153.351 1.00 70.00  ? 278 MET B N   1 
ATOM 3401 C CA  . MET B 1 204 ? 128.465 102.346 153.257 1.00 65.80  ? 278 MET B CA  1 
ATOM 3402 C C   . MET B 1 204 ? 128.074 102.435 151.787 1.00 71.84  ? 278 MET B C   1 
ATOM 3403 O O   . MET B 1 204 ? 128.370 103.429 151.117 1.00 74.58  ? 278 MET B O   1 
ATOM 3404 C CB  . MET B 1 204 ? 128.070 103.612 154.010 1.00 65.20  ? 278 MET B CB  1 
ATOM 3405 C CG  . MET B 1 204 ? 126.572 103.866 154.048 1.00 70.11  ? 278 MET B CG  1 
ATOM 3406 S SD  . MET B 1 204 ? 125.648 102.490 154.756 1.00 82.73  ? 278 MET B SD  1 
ATOM 3407 C CE  . MET B 1 204 ? 123.968 103.084 154.576 1.00 70.02  ? 278 MET B CE  1 
ATOM 3408 N N   . GLN B 1 205 ? 127.408 101.401 151.285 1.00 60.25  ? 279 GLN B N   1 
ATOM 3409 C CA  . GLN B 1 205 ? 126.998 101.357 149.891 1.00 49.34  ? 279 GLN B CA  1 
ATOM 3410 C C   . GLN B 1 205 ? 125.670 102.074 149.690 1.00 53.60  ? 279 GLN B C   1 
ATOM 3411 O O   . GLN B 1 205 ? 124.915 102.307 150.637 1.00 58.92  ? 279 GLN B O   1 
ATOM 3412 C CB  . GLN B 1 205 ? 126.877 99.914  149.401 1.00 48.01  ? 279 GLN B CB  1 
ATOM 3413 C CG  . GLN B 1 205 ? 128.146 99.103  149.529 1.00 52.19  ? 279 GLN B CG  1 
ATOM 3414 C CD  . GLN B 1 205 ? 127.990 97.703  148.977 1.00 57.83  ? 279 GLN B CD  1 
ATOM 3415 O OE1 . GLN B 1 205 ? 126.963 97.368  148.389 1.00 59.84  ? 279 GLN B OE1 1 
ATOM 3416 N NE2 . GLN B 1 205 ? 129.012 96.876  149.163 1.00 56.70  ? 279 GLN B NE2 1 
ATOM 3417 N N   . TYR B 1 206 ? 125.397 102.424 148.437 1.00 51.92  ? 280 TYR B N   1 
ATOM 3418 C CA  . TYR B 1 206 ? 124.124 103.004 148.040 1.00 47.45  ? 280 TYR B CA  1 
ATOM 3419 C C   . TYR B 1 206 ? 123.773 102.514 146.644 1.00 57.49  ? 280 TYR B C   1 
ATOM 3420 O O   . TYR B 1 206 ? 124.652 102.172 145.850 1.00 65.69  ? 280 TYR B O   1 
ATOM 3421 C CB  . TYR B 1 206 ? 124.156 104.535 148.039 1.00 46.07  ? 280 TYR B CB  1 
ATOM 3422 C CG  . TYR B 1 206 ? 124.530 105.169 149.356 1.00 50.46  ? 280 TYR B CG  1 
ATOM 3423 C CD1 . TYR B 1 206 ? 123.575 105.395 150.336 1.00 56.51  ? 280 TYR B CD1 1 
ATOM 3424 C CD2 . TYR B 1 206 ? 125.834 105.562 149.612 1.00 54.81  ? 280 TYR B CD2 1 
ATOM 3425 C CE1 . TYR B 1 206 ? 123.910 105.984 151.539 1.00 55.61  ? 280 TYR B CE1 1 
ATOM 3426 C CE2 . TYR B 1 206 ? 126.181 106.152 150.811 1.00 59.16  ? 280 TYR B CE2 1 
ATOM 3427 C CZ  . TYR B 1 206 ? 125.215 106.362 151.770 1.00 58.82  ? 280 TYR B CZ  1 
ATOM 3428 O OH  . TYR B 1 206 ? 125.558 106.950 152.966 1.00 57.32  ? 280 TYR B OH  1 
ATOM 3429 N N   . GLN B 1 207 ? 122.477 102.483 146.353 1.00 50.86  ? 281 GLN B N   1 
ATOM 3430 C CA  . GLN B 1 207 ? 121.973 102.235 145.010 1.00 46.25  ? 281 GLN B CA  1 
ATOM 3431 C C   . GLN B 1 207 ? 121.258 103.494 144.544 1.00 44.45  ? 281 GLN B C   1 
ATOM 3432 O O   . GLN B 1 207 ? 120.342 103.976 145.217 1.00 55.00  ? 281 GLN B O   1 
ATOM 3433 C CB  . GLN B 1 207 ? 121.034 101.031 144.985 1.00 48.38  ? 281 GLN B CB  1 
ATOM 3434 C CG  . GLN B 1 207 ? 121.673 99.735  145.452 1.00 49.63  ? 281 GLN B CG  1 
ATOM 3435 C CD  . GLN B 1 207 ? 122.728 99.218  144.499 1.00 58.58  ? 281 GLN B CD  1 
ATOM 3436 O OE1 . GLN B 1 207 ? 122.770 99.603  143.331 1.00 58.33  ? 281 GLN B OE1 1 
ATOM 3437 N NE2 . GLN B 1 207 ? 123.587 98.335  144.992 1.00 57.99  ? 281 GLN B NE2 1 
ATOM 3438 N N   . VAL B 1 208 ? 121.677 104.025 143.401 1.00 45.52  ? 282 VAL B N   1 
ATOM 3439 C CA  . VAL B 1 208 ? 121.191 105.301 142.895 1.00 45.30  ? 282 VAL B CA  1 
ATOM 3440 C C   . VAL B 1 208 ? 120.556 105.077 141.532 1.00 50.35  ? 282 VAL B C   1 
ATOM 3441 O O   . VAL B 1 208 ? 121.168 104.467 140.647 1.00 59.89  ? 282 VAL B O   1 
ATOM 3442 C CB  . VAL B 1 208 ? 122.323 106.337 142.806 1.00 53.35  ? 282 VAL B CB  1 
ATOM 3443 C CG1 . VAL B 1 208 ? 121.824 107.601 142.148 1.00 54.50  ? 282 VAL B CG1 1 
ATOM 3444 C CG2 . VAL B 1 208 ? 122.871 106.637 144.191 1.00 57.21  ? 282 VAL B CG2 1 
ATOM 3445 N N   . LEU B 1 209 ? 119.331 105.575 141.363 1.00 50.31  ? 283 LEU B N   1 
ATOM 3446 C CA  . LEU B 1 209 ? 118.600 105.427 140.112 1.00 48.07  ? 283 LEU B CA  1 
ATOM 3447 C C   . LEU B 1 209 ? 118.845 106.590 139.160 1.00 45.81  ? 283 LEU B C   1 
ATOM 3448 O O   . LEU B 1 209 ? 119.080 106.376 137.967 1.00 54.63  ? 283 LEU B O   1 
ATOM 3449 C CB  . LEU B 1 209 ? 117.101 105.291 140.391 1.00 52.25  ? 283 LEU B CB  1 
ATOM 3450 C CG  . LEU B 1 209 ? 116.207 105.177 139.157 1.00 48.33  ? 283 LEU B CG  1 
ATOM 3451 C CD1 . LEU B 1 209 ? 116.566 103.942 138.350 1.00 49.19  ? 283 LEU B CD1 1 
ATOM 3452 C CD2 . LEU B 1 209 ? 114.745 105.153 139.560 1.00 55.10  ? 283 LEU B CD2 1 
ATOM 3453 N N   . ASN B 1 210 ? 118.792 107.823 139.662 1.00 51.05  ? 284 ASN B N   1 
ATOM 3454 C CA  . ASN B 1 210 ? 118.941 108.984 138.791 1.00 59.51  ? 284 ASN B CA  1 
ATOM 3455 C C   . ASN B 1 210 ? 120.384 109.475 138.718 1.00 59.93  ? 284 ASN B C   1 
ATOM 3456 O O   . ASN B 1 210 ? 120.993 109.460 137.644 1.00 54.95  ? 284 ASN B O   1 
ATOM 3457 C CB  . ASN B 1 210 ? 118.022 110.121 139.255 1.00 53.42  ? 284 ASN B CB  1 
ATOM 3458 C CG  . ASN B 1 210 ? 116.575 109.896 138.871 1.00 60.32  ? 284 ASN B CG  1 
ATOM 3459 O OD1 . ASN B 1 210 ? 115.661 110.351 139.557 1.00 64.16  ? 284 ASN B OD1 1 
ATOM 3460 N ND2 . ASN B 1 210 ? 116.359 109.191 137.767 1.00 63.71  ? 284 ASN B ND2 1 
ATOM 3461 N N   . GLU B 1 211 ? 120.949 109.894 139.846 1.00 43.80  ? 285 GLU B N   1 
ATOM 3462 C CA  . GLU B 1 211 ? 122.207 110.621 139.788 1.00 38.48  ? 285 GLU B CA  1 
ATOM 3463 C C   . GLU B 1 211 ? 122.846 110.703 141.165 1.00 43.14  ? 285 GLU B C   1 
ATOM 3464 O O   . GLU B 1 211 ? 122.156 110.763 142.186 1.00 47.93  ? 285 GLU B O   1 
ATOM 3465 C CB  . GLU B 1 211 ? 121.986 112.030 139.230 1.00 46.57  ? 285 GLU B CB  1 
ATOM 3466 C CG  . GLU B 1 211 ? 121.119 112.906 140.113 1.00 54.75  ? 285 GLU B CG  1 
ATOM 3467 C CD  . GLU B 1 211 ? 120.842 114.261 139.500 1.00 56.63  ? 285 GLU B CD  1 
ATOM 3468 O OE1 . GLU B 1 211 ? 121.306 114.509 138.368 1.00 62.63  ? 285 GLU B OE1 1 
ATOM 3469 O OE2 . GLU B 1 211 ? 120.159 115.080 140.151 1.00 58.51  ? 285 GLU B OE2 1 
ATOM 3470 N N   . VAL B 1 212 ? 124.176 110.707 141.174 1.00 37.90  ? 286 VAL B N   1 
ATOM 3471 C CA  . VAL B 1 212 ? 124.971 111.062 142.342 1.00 26.07  ? 286 VAL B CA  1 
ATOM 3472 C C   . VAL B 1 212 ? 125.712 112.354 142.022 1.00 39.81  ? 286 VAL B C   1 
ATOM 3473 O O   . VAL B 1 212 ? 126.315 112.484 140.951 1.00 47.32  ? 286 VAL B O   1 
ATOM 3474 C CB  . VAL B 1 212 ? 125.937 109.933 142.748 1.00 25.77  ? 286 VAL B CB  1 
ATOM 3475 C CG1 . VAL B 1 212 ? 126.941 109.642 141.649 1.00 35.38  ? 286 VAL B CG1 1 
ATOM 3476 C CG2 . VAL B 1 212 ? 126.655 110.292 144.035 1.00 37.87  ? 286 VAL B CG2 1 
ATOM 3477 N N   . VAL B 1 213 ? 125.630 113.323 142.929 1.00 35.66  ? 287 VAL B N   1 
ATOM 3478 C CA  . VAL B 1 213 ? 126.165 114.660 142.706 1.00 25.05  ? 287 VAL B CA  1 
ATOM 3479 C C   . VAL B 1 213 ? 127.242 114.934 143.743 1.00 39.39  ? 287 VAL B C   1 
ATOM 3480 O O   . VAL B 1 213 ? 127.022 114.733 144.942 1.00 42.95  ? 287 VAL B O   1 
ATOM 3481 C CB  . VAL B 1 213 ? 125.064 115.733 142.771 1.00 31.25  ? 287 VAL B CB  1 
ATOM 3482 C CG1 . VAL B 1 213 ? 125.613 117.080 142.347 1.00 41.19  ? 287 VAL B CG1 1 
ATOM 3483 C CG2 . VAL B 1 213 ? 123.894 115.341 141.891 1.00 33.67  ? 287 VAL B CG2 1 
ATOM 3484 N N   . ILE B 1 214 ? 128.400 115.392 143.279 1.00 46.33  ? 288 ILE B N   1 
ATOM 3485 C CA  . ILE B 1 214 ? 129.515 115.766 144.141 1.00 37.95  ? 288 ILE B CA  1 
ATOM 3486 C C   . ILE B 1 214 ? 129.762 117.247 143.898 1.00 39.97  ? 288 ILE B C   1 
ATOM 3487 O O   . ILE B 1 214 ? 130.397 117.624 142.907 1.00 51.93  ? 288 ILE B O   1 
ATOM 3488 C CB  . ILE B 1 214 ? 130.775 114.939 143.865 1.00 39.53  ? 288 ILE B CB  1 
ATOM 3489 C CG1 . ILE B 1 214 ? 130.526 113.456 144.146 1.00 49.55  ? 288 ILE B CG1 1 
ATOM 3490 C CG2 . ILE B 1 214 ? 131.931 115.441 144.706 1.00 44.76  ? 288 ILE B CG2 1 
ATOM 3491 C CD1 . ILE B 1 214 ? 130.023 112.670 142.950 1.00 51.65  ? 288 ILE B CD1 1 
ATOM 3492 N N   . ASP B 1 215 ? 129.270 118.095 144.798 1.00 47.62  ? 289 ASP B N   1 
ATOM 3493 C CA  . ASP B 1 215 ? 129.323 119.533 144.597 1.00 44.32  ? 289 ASP B CA  1 
ATOM 3494 C C   . ASP B 1 215 ? 129.611 120.229 145.916 1.00 54.92  ? 289 ASP B C   1 
ATOM 3495 O O   . ASP B 1 215 ? 129.452 119.658 146.998 1.00 61.97  ? 289 ASP B O   1 
ATOM 3496 C CB  . ASP B 1 215 ? 128.017 120.065 143.998 1.00 43.95  ? 289 ASP B CB  1 
ATOM 3497 C CG  . ASP B 1 215 ? 126.823 119.816 144.894 1.00 61.70  ? 289 ASP B CG  1 
ATOM 3498 O OD1 . ASP B 1 215 ? 126.829 118.806 145.629 1.00 66.51  ? 289 ASP B OD1 1 
ATOM 3499 O OD2 . ASP B 1 215 ? 125.878 120.632 144.866 1.00 64.71  ? 289 ASP B OD2 1 
ATOM 3500 N N   . ARG B 1 216 ? 130.052 121.479 145.809 1.00 75.80  ? 290 ARG B N   1 
ATOM 3501 C CA  . ARG B 1 216 ? 130.215 122.326 146.981 1.00 74.51  ? 290 ARG B CA  1 
ATOM 3502 C C   . ARG B 1 216 ? 128.865 122.544 147.652 1.00 73.50  ? 290 ARG B C   1 
ATOM 3503 O O   . ARG B 1 216 ? 127.849 122.747 146.981 1.00 80.97  ? 290 ARG B O   1 
ATOM 3504 C CB  . ARG B 1 216 ? 130.844 123.661 146.582 1.00 74.85  ? 290 ARG B CB  1 
ATOM 3505 C CG  . ARG B 1 216 ? 129.989 124.497 145.643 1.00 76.77  ? 290 ARG B CG  1 
ATOM 3506 C CD  . ARG B 1 216 ? 130.685 125.784 145.235 1.00 79.06  ? 290 ARG B CD  1 
ATOM 3507 N NE  . ARG B 1 216 ? 129.857 126.585 144.341 1.00 85.24  ? 290 ARG B NE  1 
ATOM 3508 C CZ  . ARG B 1 216 ? 130.209 127.763 143.845 1.00 82.69  ? 290 ARG B CZ  1 
ATOM 3509 N NH1 . ARG B 1 216 ? 131.375 128.315 144.137 1.00 78.44  ? 290 ARG B NH1 1 
ATOM 3510 N NH2 . ARG B 1 216 ? 129.370 128.403 143.036 1.00 80.61  ? 290 ARG B NH2 1 
ATOM 3511 N N   . GLY B 1 217 ? 128.849 122.475 148.978 1.00 68.10  ? 291 GLY B N   1 
ATOM 3512 C CA  . GLY B 1 217 ? 127.622 122.605 149.725 1.00 74.49  ? 291 GLY B CA  1 
ATOM 3513 C C   . GLY B 1 217 ? 127.577 123.888 150.525 1.00 76.63  ? 291 GLY B C   1 
ATOM 3514 O O   . GLY B 1 217 ? 127.652 124.993 149.979 1.00 72.18  ? 291 GLY B O   1 
ATOM 3515 N N   . PRO B 1 218 ? 127.456 123.764 151.844 1.00 71.65  ? 292 PRO B N   1 
ATOM 3516 C CA  . PRO B 1 218 ? 127.477 124.958 152.697 1.00 68.86  ? 292 PRO B CA  1 
ATOM 3517 C C   . PRO B 1 218 ? 128.859 125.585 152.742 1.00 66.84  ? 292 PRO B C   1 
ATOM 3518 O O   . PRO B 1 218 ? 129.517 125.588 153.787 1.00 69.00  ? 292 PRO B O   1 
ATOM 3519 C CB  . PRO B 1 218 ? 127.059 124.418 154.072 1.00 64.83  ? 292 PRO B CB  1 
ATOM 3520 C CG  . PRO B 1 218 ? 126.405 123.095 153.792 1.00 63.56  ? 292 PRO B CG  1 
ATOM 3521 C CD  . PRO B 1 218 ? 127.124 122.549 152.603 1.00 62.68  ? 292 PRO B CD  1 
ATOM 3522 N N   . SER B 1 219 ? 129.307 126.118 151.611 1.00 69.35  ? 293 SER B N   1 
ATOM 3523 C CA  . SER B 1 219 ? 130.644 126.681 151.487 1.00 74.29  ? 293 SER B CA  1 
ATOM 3524 C C   . SER B 1 219 ? 130.657 127.611 150.280 1.00 77.27  ? 293 SER B C   1 
ATOM 3525 O O   . SER B 1 219 ? 129.606 127.949 149.725 1.00 79.30  ? 293 SER B O   1 
ATOM 3526 C CB  . SER B 1 219 ? 131.697 125.573 151.370 1.00 75.22  ? 293 SER B CB  1 
ATOM 3527 O OG  . SER B 1 219 ? 131.829 124.859 152.587 1.00 70.55  ? 293 SER B OG  1 
ATOM 3528 N N   . SER B 1 220 ? 131.853 128.022 149.870 1.00 84.61  ? 294 SER B N   1 
ATOM 3529 C CA  . SER B 1 220 ? 132.020 128.960 148.770 1.00 86.13  ? 294 SER B CA  1 
ATOM 3530 C C   . SER B 1 220 ? 133.210 128.508 147.931 1.00 84.76  ? 294 SER B C   1 
ATOM 3531 O O   . SER B 1 220 ? 133.690 127.377 148.059 1.00 86.96  ? 294 SER B O   1 
ATOM 3532 C CB  . SER B 1 220 ? 132.189 130.391 149.299 1.00 86.30  ? 294 SER B CB  1 
ATOM 3533 O OG  . SER B 1 220 ? 133.312 130.488 150.158 1.00 87.65  ? 294 SER B OG  1 
ATOM 3534 N N   . LEU B 1 222 ? 135.553 127.578 144.480 1.00 80.24  ? 296 LEU B N   1 
ATOM 3535 C CA  . LEU B 1 222 ? 135.409 126.517 143.497 1.00 82.10  ? 296 LEU B CA  1 
ATOM 3536 C C   . LEU B 1 222 ? 135.661 125.164 144.162 1.00 83.58  ? 296 LEU B C   1 
ATOM 3537 O O   . LEU B 1 222 ? 135.920 125.076 145.365 1.00 87.05  ? 296 LEU B O   1 
ATOM 3538 C CB  . LEU B 1 222 ? 136.352 126.760 142.321 1.00 80.82  ? 296 LEU B CB  1 
ATOM 3539 C CG  . LEU B 1 222 ? 136.028 127.963 141.435 1.00 81.24  ? 296 LEU B CG  1 
ATOM 3540 C CD1 . LEU B 1 222 ? 137.042 128.090 140.309 1.00 81.47  ? 296 LEU B CD1 1 
ATOM 3541 C CD2 . LEU B 1 222 ? 134.617 127.853 140.879 1.00 80.19  ? 296 LEU B CD2 1 
ATOM 3542 N N   . SER B 1 223 ? 135.588 124.091 143.378 1.00 81.57  ? 297 SER B N   1 
ATOM 3543 C CA  . SER B 1 223 ? 135.833 122.741 143.870 1.00 81.78  ? 297 SER B CA  1 
ATOM 3544 C C   . SER B 1 223 ? 136.862 122.073 142.972 1.00 84.63  ? 297 SER B C   1 
ATOM 3545 O O   . SER B 1 223 ? 136.673 122.003 141.754 1.00 81.51  ? 297 SER B O   1 
ATOM 3546 C CB  . SER B 1 223 ? 134.540 121.922 143.907 1.00 81.02  ? 297 SER B CB  1 
ATOM 3547 O OG  . SER B 1 223 ? 133.573 122.536 144.741 1.00 79.92  ? 297 SER B OG  1 
ATOM 3548 N N   . ASN B 1 224 ? 137.942 121.580 143.571 1.00 77.64  ? 298 ASN B N   1 
ATOM 3549 C CA  . ASN B 1 224 ? 139.001 120.874 142.853 1.00 71.23  ? 298 ASN B CA  1 
ATOM 3550 C C   . ASN B 1 224 ? 138.952 119.411 143.284 1.00 72.81  ? 298 ASN B C   1 
ATOM 3551 O O   . ASN B 1 224 ? 139.531 119.028 144.302 1.00 74.78  ? 298 ASN B O   1 
ATOM 3552 C CB  . ASN B 1 224 ? 140.362 121.498 143.128 1.00 67.69  ? 298 ASN B CB  1 
ATOM 3553 C CG  . ASN B 1 224 ? 140.479 122.901 142.574 1.00 73.71  ? 298 ASN B CG  1 
ATOM 3554 O OD1 . ASN B 1 224 ? 140.957 123.102 141.458 1.00 73.23  ? 298 ASN B OD1 1 
ATOM 3555 N ND2 . ASN B 1 224 ? 140.039 123.884 143.351 1.00 74.78  ? 298 ASN B ND2 1 
ATOM 3556 N N   . VAL B 1 225 ? 138.257 118.594 142.498 1.00 62.68  ? 299 VAL B N   1 
ATOM 3557 C CA  . VAL B 1 225 ? 138.077 117.178 142.787 1.00 58.97  ? 299 VAL B CA  1 
ATOM 3558 C C   . VAL B 1 225 ? 138.498 116.376 141.562 1.00 59.94  ? 299 VAL B C   1 
ATOM 3559 O O   . VAL B 1 225 ? 138.252 116.786 140.423 1.00 57.69  ? 299 VAL B O   1 
ATOM 3560 C CB  . VAL B 1 225 ? 136.621 116.869 143.200 1.00 56.91  ? 299 VAL B CB  1 
ATOM 3561 C CG1 . VAL B 1 225 ? 135.659 117.123 142.056 1.00 62.31  ? 299 VAL B CG1 1 
ATOM 3562 C CG2 . VAL B 1 225 ? 136.495 115.450 143.713 1.00 57.77  ? 299 VAL B CG2 1 
ATOM 3563 N N   . ASP B 1 226 ? 139.160 115.247 141.800 1.00 65.48  ? 300 ASP B N   1 
ATOM 3564 C CA  . ASP B 1 226 ? 139.712 114.418 140.740 1.00 61.77  ? 300 ASP B CA  1 
ATOM 3565 C C   . ASP B 1 226 ? 138.775 113.264 140.409 1.00 63.68  ? 300 ASP B C   1 
ATOM 3566 O O   . ASP B 1 226 ? 138.096 112.719 141.283 1.00 71.47  ? 300 ASP B O   1 
ATOM 3567 C CB  . ASP B 1 226 ? 141.083 113.869 141.138 1.00 68.45  ? 300 ASP B CB  1 
ATOM 3568 C CG  . ASP B 1 226 ? 142.116 114.961 141.327 1.00 74.34  ? 300 ASP B CG  1 
ATOM 3569 O OD1 . ASP B 1 226 ? 141.770 116.147 141.143 1.00 72.79  ? 300 ASP B OD1 1 
ATOM 3570 O OD2 . ASP B 1 226 ? 143.276 114.635 141.658 1.00 74.40  ? 300 ASP B OD2 1 
ATOM 3571 N N   . VAL B 1 227 ? 138.747 112.896 139.132 1.00 55.35  ? 301 VAL B N   1 
ATOM 3572 C CA  . VAL B 1 227 ? 137.912 111.812 138.630 1.00 51.95  ? 301 VAL B CA  1 
ATOM 3573 C C   . VAL B 1 227 ? 138.826 110.770 138.004 1.00 55.57  ? 301 VAL B C   1 
ATOM 3574 O O   . VAL B 1 227 ? 139.607 111.087 137.098 1.00 67.16  ? 301 VAL B O   1 
ATOM 3575 C CB  . VAL B 1 227 ? 136.879 112.312 137.609 1.00 51.29  ? 301 VAL B CB  1 
ATOM 3576 C CG1 . VAL B 1 227 ? 136.077 111.149 137.058 1.00 51.12  ? 301 VAL B CG1 1 
ATOM 3577 C CG2 . VAL B 1 227 ? 135.966 113.348 138.238 1.00 56.80  ? 301 VAL B CG2 1 
ATOM 3578 N N   . TYR B 1 228 ? 138.729 109.533 138.480 1.00 56.90  ? 302 TYR B N   1 
ATOM 3579 C CA  . TYR B 1 228 ? 139.530 108.429 137.970 1.00 56.32  ? 302 TYR B CA  1 
ATOM 3580 C C   . TYR B 1 228 ? 138.637 107.411 137.277 1.00 59.38  ? 302 TYR B C   1 
ATOM 3581 O O   . TYR B 1 228 ? 137.553 107.082 137.769 1.00 63.40  ? 302 TYR B O   1 
ATOM 3582 C CB  . TYR B 1 228 ? 140.317 107.747 139.091 1.00 59.67  ? 302 TYR B CB  1 
ATOM 3583 C CG  . TYR B 1 228 ? 141.362 108.625 139.733 1.00 62.58  ? 302 TYR B CG  1 
ATOM 3584 C CD1 . TYR B 1 228 ? 141.032 109.491 140.765 1.00 61.76  ? 302 TYR B CD1 1 
ATOM 3585 C CD2 . TYR B 1 228 ? 142.680 108.592 139.304 1.00 67.13  ? 302 TYR B CD2 1 
ATOM 3586 C CE1 . TYR B 1 228 ? 141.985 110.295 141.353 1.00 58.07  ? 302 TYR B CE1 1 
ATOM 3587 C CE2 . TYR B 1 228 ? 143.640 109.394 139.886 1.00 66.88  ? 302 TYR B CE2 1 
ATOM 3588 C CZ  . TYR B 1 228 ? 143.287 110.244 140.909 1.00 61.62  ? 302 TYR B CZ  1 
ATOM 3589 O OH  . TYR B 1 228 ? 144.242 111.044 141.492 1.00 64.38  ? 302 TYR B OH  1 
ATOM 3590 N N   . LEU B 1 229 ? 139.098 106.917 136.132 1.00 56.00  ? 303 LEU B N   1 
ATOM 3591 C CA  . LEU B 1 229 ? 138.388 105.907 135.355 1.00 56.64  ? 303 LEU B CA  1 
ATOM 3592 C C   . LEU B 1 229 ? 139.314 104.714 135.166 1.00 57.88  ? 303 LEU B C   1 
ATOM 3593 O O   . LEU B 1 229 ? 140.297 104.800 134.421 1.00 59.81  ? 303 LEU B O   1 
ATOM 3594 C CB  . LEU B 1 229 ? 137.937 106.471 134.010 1.00 56.91  ? 303 LEU B CB  1 
ATOM 3595 C CG  . LEU B 1 229 ? 136.817 105.714 133.303 1.00 56.31  ? 303 LEU B CG  1 
ATOM 3596 C CD1 . LEU B 1 229 ? 135.570 105.752 134.144 1.00 58.97  ? 303 LEU B CD1 1 
ATOM 3597 C CD2 . LEU B 1 229 ? 136.546 106.296 131.936 1.00 52.77  ? 303 LEU B CD2 1 
ATOM 3598 N N   . ASP B 1 230 ? 138.997 103.606 135.835 1.00 65.48  ? 304 ASP B N   1 
ATOM 3599 C CA  . ASP B 1 230 ? 139.811 102.391 135.788 1.00 64.49  ? 304 ASP B CA  1 
ATOM 3600 C C   . ASP B 1 230 ? 141.256 102.673 136.190 1.00 64.94  ? 304 ASP B C   1 
ATOM 3601 O O   . ASP B 1 230 ? 142.204 102.155 135.595 1.00 66.47  ? 304 ASP B O   1 
ATOM 3602 C CB  . ASP B 1 230 ? 139.744 101.737 134.408 1.00 65.71  ? 304 ASP B CB  1 
ATOM 3603 C CG  . ASP B 1 230 ? 138.391 101.123 134.122 1.00 69.79  ? 304 ASP B CG  1 
ATOM 3604 O OD1 . ASP B 1 230 ? 137.529 101.142 135.024 1.00 71.92  ? 304 ASP B OD1 1 
ATOM 3605 O OD2 . ASP B 1 230 ? 138.188 100.621 132.996 1.00 68.22  ? 304 ASP B OD2 1 
ATOM 3606 N N   . GLY B 1 231 ? 141.426 103.505 137.214 1.00 70.89  ? 305 GLY B N   1 
ATOM 3607 C CA  . GLY B 1 231 ? 142.734 103.807 137.752 1.00 71.89  ? 305 GLY B CA  1 
ATOM 3608 C C   . GLY B 1 231 ? 143.485 104.923 137.061 1.00 71.58  ? 305 GLY B C   1 
ATOM 3609 O O   . GLY B 1 231 ? 144.593 105.260 137.498 1.00 77.55  ? 305 GLY B O   1 
ATOM 3610 N N   . HIS B 1 232 ? 142.930 105.507 136.006 1.00 68.61  ? 306 HIS B N   1 
ATOM 3611 C CA  . HIS B 1 232 ? 143.580 106.582 135.270 1.00 72.64  ? 306 HIS B CA  1 
ATOM 3612 C C   . HIS B 1 232 ? 142.846 107.891 135.519 1.00 73.11  ? 306 HIS B C   1 
ATOM 3613 O O   . HIS B 1 232 ? 141.617 107.950 135.409 1.00 79.13  ? 306 HIS B O   1 
ATOM 3614 C CB  . HIS B 1 232 ? 143.621 106.274 133.772 1.00 73.77  ? 306 HIS B CB  1 
ATOM 3615 C CG  . HIS B 1 232 ? 144.330 104.999 133.438 1.00 75.89  ? 306 HIS B CG  1 
ATOM 3616 N ND1 . HIS B 1 232 ? 144.198 104.372 132.218 1.00 76.45  ? 306 HIS B ND1 1 
ATOM 3617 C CD2 . HIS B 1 232 ? 145.185 104.239 134.162 1.00 75.07  ? 306 HIS B CD2 1 
ATOM 3618 C CE1 . HIS B 1 232 ? 144.937 103.276 132.207 1.00 76.74  ? 306 HIS B CE1 1 
ATOM 3619 N NE2 . HIS B 1 232 ? 145.546 103.173 133.375 1.00 79.08  ? 306 HIS B NE2 1 
ATOM 3620 N N   . LEU B 1 233 ? 143.602 108.934 135.850 1.00 55.35  ? 307 LEU B N   1 
ATOM 3621 C CA  . LEU B 1 233 ? 143.024 110.252 136.084 1.00 57.02  ? 307 LEU B CA  1 
ATOM 3622 C C   . LEU B 1 233 ? 142.584 110.847 134.754 1.00 62.55  ? 307 LEU B C   1 
ATOM 3623 O O   . LEU B 1 233 ? 143.405 111.385 134.004 1.00 68.87  ? 307 LEU B O   1 
ATOM 3624 C CB  . LEU B 1 233 ? 144.039 111.153 136.777 1.00 59.91  ? 307 LEU B CB  1 
ATOM 3625 C CG  . LEU B 1 233 ? 143.626 112.605 137.017 1.00 65.45  ? 307 LEU B CG  1 
ATOM 3626 C CD1 . LEU B 1 233 ? 142.408 112.672 137.923 1.00 64.48  ? 307 LEU B CD1 1 
ATOM 3627 C CD2 . LEU B 1 233 ? 144.780 113.398 137.608 1.00 63.53  ? 307 LEU B CD2 1 
ATOM 3628 N N   . ILE B 1 234 ? 141.291 110.749 134.454 1.00 57.79  ? 308 ILE B N   1 
ATOM 3629 C CA  . ILE B 1 234 ? 140.794 111.258 133.182 1.00 65.47  ? 308 ILE B CA  1 
ATOM 3630 C C   . ILE B 1 234 ? 140.709 112.778 133.201 1.00 69.08  ? 308 ILE B C   1 
ATOM 3631 O O   . ILE B 1 234 ? 141.093 113.445 132.234 1.00 76.56  ? 308 ILE B O   1 
ATOM 3632 C CB  . ILE B 1 234 ? 139.438 110.617 132.833 1.00 65.64  ? 308 ILE B CB  1 
ATOM 3633 C CG1 . ILE B 1 234 ? 138.495 110.641 134.036 1.00 64.45  ? 308 ILE B CG1 1 
ATOM 3634 C CG2 . ILE B 1 234 ? 139.638 109.197 132.330 1.00 65.58  ? 308 ILE B CG2 1 
ATOM 3635 C CD1 . ILE B 1 234 ? 137.148 110.011 133.761 1.00 65.38  ? 308 ILE B CD1 1 
ATOM 3636 N N   . THR B 1 235 ? 140.213 113.352 134.295 1.00 56.68  ? 309 THR B N   1 
ATOM 3637 C CA  . THR B 1 235 ? 140.013 114.793 134.340 1.00 64.16  ? 309 THR B CA  1 
ATOM 3638 C C   . THR B 1 235 ? 139.949 115.260 135.784 1.00 66.96  ? 309 THR B C   1 
ATOM 3639 O O   . THR B 1 235 ? 139.719 114.474 136.706 1.00 73.42  ? 309 THR B O   1 
ATOM 3640 C CB  . THR B 1 235 ? 138.739 115.208 133.599 1.00 69.42  ? 309 THR B CB  1 
ATOM 3641 O OG1 . THR B 1 235 ? 138.606 116.634 133.634 1.00 73.35  ? 309 THR B OG1 1 
ATOM 3642 C CG2 . THR B 1 235 ? 137.517 114.575 134.247 1.00 68.33  ? 309 THR B CG2 1 
ATOM 3643 N N   . THR B 1 236 ? 140.160 116.562 135.960 1.00 66.53  ? 310 THR B N   1 
ATOM 3644 C CA  . THR B 1 236 ? 139.959 117.253 137.229 1.00 68.16  ? 310 THR B CA  1 
ATOM 3645 C C   . THR B 1 236 ? 138.976 118.386 136.973 1.00 69.89  ? 310 THR B C   1 
ATOM 3646 O O   . THR B 1 236 ? 139.299 119.343 136.262 1.00 66.51  ? 310 THR B O   1 
ATOM 3647 C CB  . THR B 1 236 ? 141.276 117.783 137.790 1.00 70.00  ? 310 THR B CB  1 
ATOM 3648 O OG1 . THR B 1 236 ? 142.152 116.686 138.077 1.00 73.27  ? 310 THR B OG1 1 
ATOM 3649 C CG2 . THR B 1 236 ? 141.030 118.578 139.063 1.00 70.05  ? 310 THR B CG2 1 
ATOM 3650 N N   . VAL B 1 237 ? 137.785 118.282 137.548 1.00 74.82  ? 311 VAL B N   1 
ATOM 3651 C CA  . VAL B 1 237 ? 136.706 119.221 137.268 1.00 73.54  ? 311 VAL B CA  1 
ATOM 3652 C C   . VAL B 1 237 ? 136.741 120.354 138.286 1.00 72.67  ? 311 VAL B C   1 
ATOM 3653 O O   . VAL B 1 237 ? 136.854 120.121 139.495 1.00 74.48  ? 311 VAL B O   1 
ATOM 3654 C CB  . VAL B 1 237 ? 135.342 118.508 137.256 1.00 74.91  ? 311 VAL B CB  1 
ATOM 3655 C CG1 . VAL B 1 237 ? 135.016 117.908 138.612 1.00 71.70  ? 311 VAL B CG1 1 
ATOM 3656 C CG2 . VAL B 1 237 ? 134.246 119.468 136.815 1.00 72.79  ? 311 VAL B CG2 1 
ATOM 3657 N N   . GLN B 1 238 ? 136.684 121.586 137.789 1.00 69.76  ? 312 GLN B N   1 
ATOM 3658 C CA  . GLN B 1 238 ? 136.652 122.780 138.619 1.00 69.87  ? 312 GLN B CA  1 
ATOM 3659 C C   . GLN B 1 238 ? 135.378 123.553 138.318 1.00 70.44  ? 312 GLN B C   1 
ATOM 3660 O O   . GLN B 1 238 ? 135.077 123.833 137.153 1.00 73.13  ? 312 GLN B O   1 
ATOM 3661 C CB  . GLN B 1 238 ? 137.880 123.658 138.377 1.00 72.49  ? 312 GLN B CB  1 
ATOM 3662 C CG  . GLN B 1 238 ? 139.197 122.968 138.676 1.00 73.88  ? 312 GLN B CG  1 
ATOM 3663 C CD  . GLN B 1 238 ? 140.393 123.856 138.407 1.00 77.48  ? 312 GLN B CD  1 
ATOM 3664 O OE1 . GLN B 1 238 ? 140.248 125.050 138.148 1.00 77.19  ? 312 GLN B OE1 1 
ATOM 3665 N NE2 . GLN B 1 238 ? 141.586 123.276 138.469 1.00 74.74  ? 312 GLN B NE2 1 
ATOM 3666 N N   . GLY B 1 239 ? 134.647 123.893 139.356 1.00 60.22  ? 313 GLY B N   1 
ATOM 3667 C CA  . GLY B 1 239 ? 133.357 124.530 139.224 1.00 60.76  ? 313 GLY B CA  1 
ATOM 3668 C C   . GLY B 1 239 ? 132.462 124.115 140.377 1.00 61.47  ? 313 GLY B C   1 
ATOM 3669 O O   . GLY B 1 239 ? 132.937 123.872 141.483 1.00 65.37  ? 313 GLY B O   1 
ATOM 3670 N N   . ASP B 1 240 ? 131.161 124.046 140.093 1.00 53.88  ? 314 ASP B N   1 
ATOM 3671 C CA  . ASP B 1 240 ? 130.220 123.622 141.122 1.00 57.04  ? 314 ASP B CA  1 
ATOM 3672 C C   . ASP B 1 240 ? 130.405 122.150 141.470 1.00 56.06  ? 314 ASP B C   1 
ATOM 3673 O O   . ASP B 1 240 ? 130.434 121.790 142.651 1.00 65.34  ? 314 ASP B O   1 
ATOM 3674 C CB  . ASP B 1 240 ? 128.788 123.900 140.677 1.00 60.09  ? 314 ASP B CB  1 
ATOM 3675 C CG  . ASP B 1 240 ? 128.502 125.380 140.534 1.00 64.62  ? 314 ASP B CG  1 
ATOM 3676 O OD1 . ASP B 1 240 ? 129.409 126.190 140.813 1.00 65.27  ? 314 ASP B OD1 1 
ATOM 3677 O OD2 . ASP B 1 240 ? 127.369 125.735 140.144 1.00 64.07  ? 314 ASP B OD2 1 
ATOM 3678 N N   . GLY B 1 241 ? 130.541 121.289 140.469 1.00 40.30  ? 315 GLY B N   1 
ATOM 3679 C CA  . GLY B 1 241 ? 130.785 119.884 140.743 1.00 42.93  ? 315 GLY B CA  1 
ATOM 3680 C C   . GLY B 1 241 ? 130.465 119.018 139.535 1.00 39.56  ? 315 GLY B C   1 
ATOM 3681 O O   . GLY B 1 241 ? 130.358 119.506 138.413 1.00 38.30  ? 315 GLY B O   1 
ATOM 3682 N N   . VAL B 1 242 ? 130.317 117.722 139.807 1.00 34.85  ? 316 VAL B N   1 
ATOM 3683 C CA  . VAL B 1 242 ? 130.084 116.703 138.790 1.00 30.79  ? 316 VAL B CA  1 
ATOM 3684 C C   . VAL B 1 242 ? 128.818 115.938 139.158 1.00 40.96  ? 316 VAL B C   1 
ATOM 3685 O O   . VAL B 1 242 ? 128.544 115.703 140.339 1.00 44.80  ? 316 VAL B O   1 
ATOM 3686 C CB  . VAL B 1 242 ? 131.296 115.756 138.653 1.00 29.50  ? 316 VAL B CB  1 
ATOM 3687 C CG1 . VAL B 1 242 ? 131.603 115.074 139.975 1.00 36.67  ? 316 VAL B CG1 1 
ATOM 3688 C CG2 . VAL B 1 242 ? 131.062 114.730 137.556 1.00 43.18  ? 316 VAL B CG2 1 
ATOM 3689 N N   . ILE B 1 243 ? 128.037 115.568 138.144 1.00 37.99  ? 317 ILE B N   1 
ATOM 3690 C CA  . ILE B 1 243 ? 126.664 115.116 138.345 1.00 27.92  ? 317 ILE B CA  1 
ATOM 3691 C C   . ILE B 1 243 ? 126.460 113.718 137.760 1.00 32.30  ? 317 ILE B C   1 
ATOM 3692 O O   . ILE B 1 243 ? 125.407 113.417 137.186 1.00 51.36  ? 317 ILE B O   1 
ATOM 3693 C CB  . ILE B 1 243 ? 125.678 116.156 137.773 1.00 33.74  ? 317 ILE B CB  1 
ATOM 3694 C CG1 . ILE B 1 243 ? 124.248 115.890 138.229 1.00 40.43  ? 317 ILE B CG1 1 
ATOM 3695 C CG2 . ILE B 1 243 ? 125.741 116.231 136.266 1.00 41.15  ? 317 ILE B CG2 1 
ATOM 3696 C CD1 . ILE B 1 243 ? 123.345 117.030 137.930 1.00 42.84  ? 317 ILE B CD1 1 
ATOM 3697 N N   . VAL B 1 244 ? 127.475 112.859 137.887 1.00 21.48  ? 318 VAL B N   1 
ATOM 3698 C CA  . VAL B 1 244 ? 127.466 111.501 137.338 1.00 23.39  ? 318 VAL B CA  1 
ATOM 3699 C C   . VAL B 1 244 ? 126.115 110.825 137.541 1.00 31.24  ? 318 VAL B C   1 
ATOM 3700 O O   . VAL B 1 244 ? 125.594 110.774 138.661 1.00 43.93  ? 318 VAL B O   1 
ATOM 3701 C CB  . VAL B 1 244 ? 128.583 110.654 137.971 1.00 28.31  ? 318 VAL B CB  1 
ATOM 3702 C CG1 . VAL B 1 244 ? 128.364 109.186 137.670 1.00 34.24  ? 318 VAL B CG1 1 
ATOM 3703 C CG2 . VAL B 1 244 ? 129.940 111.110 137.470 1.00 38.91  ? 318 VAL B CG2 1 
ATOM 3704 N N   . SER B 1 245 ? 125.544 110.298 136.458 1.00 37.83  ? 319 SER B N   1 
ATOM 3705 C CA  . SER B 1 245 ? 124.149 109.884 136.452 1.00 27.70  ? 319 SER B CA  1 
ATOM 3706 C C   . SER B 1 245 ? 123.946 108.712 135.504 1.00 39.82  ? 319 SER B C   1 
ATOM 3707 O O   . SER B 1 245 ? 124.774 108.436 134.634 1.00 50.35  ? 319 SER B O   1 
ATOM 3708 C CB  . SER B 1 245 ? 123.236 111.043 136.044 1.00 36.86  ? 319 SER B CB  1 
ATOM 3709 O OG  . SER B 1 245 ? 123.560 111.505 134.746 1.00 34.47  ? 319 SER B OG  1 
ATOM 3710 N N   . THR B 1 246 ? 122.821 108.028 135.689 1.00 48.03  ? 320 THR B N   1 
ATOM 3711 C CA  . THR B 1 246 ? 122.388 106.952 134.809 1.00 41.48  ? 320 THR B CA  1 
ATOM 3712 C C   . THR B 1 246 ? 121.668 107.528 133.596 1.00 50.13  ? 320 THR B C   1 
ATOM 3713 O O   . THR B 1 246 ? 121.361 108.721 133.547 1.00 57.38  ? 320 THR B O   1 
ATOM 3714 C CB  . THR B 1 246 ? 121.468 106.002 135.570 1.00 40.19  ? 320 THR B CB  1 
ATOM 3715 O OG1 . THR B 1 246 ? 120.306 106.714 136.010 1.00 48.91  ? 320 THR B OG1 1 
ATOM 3716 C CG2 . THR B 1 246 ? 122.172 105.421 136.769 1.00 50.64  ? 320 THR B CG2 1 
ATOM 3717 N N   . PRO B 1 247 ? 121.394 106.702 132.580 1.00 45.37  ? 321 PRO B N   1 
ATOM 3718 C CA  . PRO B 1 247 ? 120.555 107.179 131.470 1.00 38.77  ? 321 PRO B CA  1 
ATOM 3719 C C   . PRO B 1 247 ? 119.178 107.639 131.909 1.00 50.67  ? 321 PRO B C   1 
ATOM 3720 O O   . PRO B 1 247 ? 118.620 108.559 131.300 1.00 51.00  ? 321 PRO B O   1 
ATOM 3721 C CB  . PRO B 1 247 ? 120.473 105.956 130.551 1.00 44.57  ? 321 PRO B CB  1 
ATOM 3722 C CG  . PRO B 1 247 ? 121.725 105.225 130.810 1.00 51.83  ? 321 PRO B CG  1 
ATOM 3723 C CD  . PRO B 1 247 ? 122.009 105.400 132.271 1.00 51.67  ? 321 PRO B CD  1 
ATOM 3724 N N   . THR B 1 248 ? 118.606 107.022 132.945 1.00 57.78  ? 322 THR B N   1 
ATOM 3725 C CA  . THR B 1 248 ? 117.319 107.479 133.456 1.00 50.67  ? 322 THR B CA  1 
ATOM 3726 C C   . THR B 1 248 ? 117.423 108.866 134.072 1.00 52.82  ? 322 THR B C   1 
ATOM 3727 O O   . THR B 1 248 ? 116.454 109.632 134.038 1.00 57.12  ? 322 THR B O   1 
ATOM 3728 C CB  . THR B 1 248 ? 116.775 106.489 134.482 1.00 46.33  ? 322 THR B CB  1 
ATOM 3729 O OG1 . THR B 1 248 ? 117.568 106.550 135.673 1.00 56.89  ? 322 THR B OG1 1 
ATOM 3730 C CG2 . THR B 1 248 ? 116.829 105.085 133.924 1.00 52.37  ? 322 THR B CG2 1 
ATOM 3731 N N   . GLY B 1 249 ? 118.578 109.204 134.636 1.00 46.39  ? 323 GLY B N   1 
ATOM 3732 C CA  . GLY B 1 249 ? 118.820 110.525 135.168 1.00 43.53  ? 323 GLY B CA  1 
ATOM 3733 C C   . GLY B 1 249 ? 119.229 111.559 134.151 1.00 51.50  ? 323 GLY B C   1 
ATOM 3734 O O   . GLY B 1 249 ? 119.459 112.714 134.516 1.00 55.42  ? 323 GLY B O   1 
ATOM 3735 N N   . SER B 1 250 ? 119.334 111.174 132.876 1.00 57.67  ? 324 SER B N   1 
ATOM 3736 C CA  . SER B 1 250 ? 119.690 112.134 131.837 1.00 57.60  ? 324 SER B CA  1 
ATOM 3737 C C   . SER B 1 250 ? 118.638 113.223 131.697 1.00 61.20  ? 324 SER B C   1 
ATOM 3738 O O   . SER B 1 250 ? 118.957 114.343 131.282 1.00 64.18  ? 324 SER B O   1 
ATOM 3739 C CB  . SER B 1 250 ? 119.882 111.416 130.502 1.00 59.93  ? 324 SER B CB  1 
ATOM 3740 O OG  . SER B 1 250 ? 118.697 110.745 130.112 1.00 62.59  ? 324 SER B OG  1 
ATOM 3741 N N   . THR B 1 251 ? 117.387 112.917 132.028 1.00 58.26  ? 325 THR B N   1 
ATOM 3742 C CA  . THR B 1 251 ? 116.308 113.893 132.016 1.00 60.19  ? 325 THR B CA  1 
ATOM 3743 C C   . THR B 1 251 ? 116.111 114.560 133.370 1.00 61.28  ? 325 THR B C   1 
ATOM 3744 O O   . THR B 1 251 ? 115.245 115.431 133.499 1.00 64.32  ? 325 THR B O   1 
ATOM 3745 C CB  . THR B 1 251 ? 115.005 113.225 131.575 1.00 65.95  ? 325 THR B CB  1 
ATOM 3746 O OG1 . THR B 1 251 ? 114.651 112.201 132.512 1.00 63.15  ? 325 THR B OG1 1 
ATOM 3747 C CG2 . THR B 1 251 ? 115.170 112.603 130.198 1.00 61.90  ? 325 THR B CG2 1 
ATOM 3748 N N   . ALA B 1 252 ? 116.891 114.172 134.369 1.00 56.67  ? 326 ALA B N   1 
ATOM 3749 C CA  . ALA B 1 252 ? 116.836 114.745 135.705 1.00 56.89  ? 326 ALA B CA  1 
ATOM 3750 C C   . ALA B 1 252 ? 117.734 115.982 135.750 1.00 55.56  ? 326 ALA B C   1 
ATOM 3751 O O   . ALA B 1 252 ? 118.093 116.539 134.710 1.00 57.83  ? 326 ALA B O   1 
ATOM 3752 C CB  . ALA B 1 252 ? 117.225 113.687 136.742 1.00 53.60  ? 326 ALA B CB  1 
ATOM 3753 N N   . TYR B 1 253 ? 118.079 116.443 136.956 1.00 45.79  ? 327 TYR B N   1 
ATOM 3754 C CA  . TYR B 1 253 ? 118.926 117.620 137.127 1.00 44.32  ? 327 TYR B CA  1 
ATOM 3755 C C   . TYR B 1 253 ? 120.222 117.543 136.321 1.00 49.01  ? 327 TYR B C   1 
ATOM 3756 O O   . TYR B 1 253 ? 120.872 118.572 136.111 1.00 57.91  ? 327 TYR B O   1 
ATOM 3757 C CB  . TYR B 1 253 ? 119.204 117.809 138.625 1.00 50.00  ? 327 TYR B CB  1 
ATOM 3758 C CG  . TYR B 1 253 ? 120.197 118.893 138.984 1.00 50.98  ? 327 TYR B CG  1 
ATOM 3759 C CD1 . TYR B 1 253 ? 120.058 120.186 138.499 1.00 54.25  ? 327 TYR B CD1 1 
ATOM 3760 C CD2 . TYR B 1 253 ? 121.240 118.634 139.858 1.00 46.10  ? 327 TYR B CD2 1 
ATOM 3761 C CE1 . TYR B 1 253 ? 120.961 121.175 138.838 1.00 50.07  ? 327 TYR B CE1 1 
ATOM 3762 C CE2 . TYR B 1 253 ? 122.146 119.611 140.200 1.00 46.29  ? 327 TYR B CE2 1 
ATOM 3763 C CZ  . TYR B 1 253 ? 122.002 120.880 139.693 1.00 49.21  ? 327 TYR B CZ  1 
ATOM 3764 O OH  . TYR B 1 253 ? 122.905 121.856 140.043 1.00 56.35  ? 327 TYR B OH  1 
ATOM 3765 N N   . ALA B 1 254 ? 120.604 116.355 135.844 1.00 47.36  ? 328 ALA B N   1 
ATOM 3766 C CA  . ALA B 1 254 ? 121.712 116.264 134.899 1.00 43.81  ? 328 ALA B CA  1 
ATOM 3767 C C   . ALA B 1 254 ? 121.399 116.985 133.596 1.00 37.44  ? 328 ALA B C   1 
ATOM 3768 O O   . ALA B 1 254 ? 122.310 117.496 132.937 1.00 42.00  ? 328 ALA B O   1 
ATOM 3769 C CB  . ALA B 1 254 ? 122.053 114.800 134.624 1.00 41.13  ? 328 ALA B CB  1 
ATOM 3770 N N   . ALA B 1 255 ? 120.124 117.029 133.204 1.00 43.79  ? 329 ALA B N   1 
ATOM 3771 C CA  . ALA B 1 255 ? 119.749 117.733 131.982 1.00 41.30  ? 329 ALA B CA  1 
ATOM 3772 C C   . ALA B 1 255 ? 119.947 119.235 132.125 1.00 45.66  ? 329 ALA B C   1 
ATOM 3773 O O   . ALA B 1 255 ? 120.324 119.911 131.162 1.00 56.16  ? 329 ALA B O   1 
ATOM 3774 C CB  . ALA B 1 255 ? 118.300 117.421 131.614 1.00 45.45  ? 329 ALA B CB  1 
ATOM 3775 N N   . ALA B 1 256 ? 119.694 119.775 133.318 1.00 38.55  ? 330 ALA B N   1 
ATOM 3776 C CA  . ALA B 1 256 ? 119.876 121.203 133.539 1.00 40.60  ? 330 ALA B CA  1 
ATOM 3777 C C   . ALA B 1 256 ? 121.334 121.623 133.440 1.00 49.76  ? 330 ALA B C   1 
ATOM 3778 O O   . ALA B 1 256 ? 121.612 122.810 133.249 1.00 52.66  ? 330 ALA B O   1 
ATOM 3779 C CB  . ALA B 1 256 ? 119.312 121.599 134.903 1.00 37.50  ? 330 ALA B CB  1 
ATOM 3780 N N   . ALA B 1 257 ? 122.264 120.681 133.551 1.00 54.21  ? 331 ALA B N   1 
ATOM 3781 C CA  . ALA B 1 257 ? 123.687 120.974 133.505 1.00 43.85  ? 331 ALA B CA  1 
ATOM 3782 C C   . ALA B 1 257 ? 124.257 120.930 132.095 1.00 44.41  ? 331 ALA B C   1 
ATOM 3783 O O   . ALA B 1 257 ? 125.471 121.083 131.928 1.00 53.17  ? 331 ALA B O   1 
ATOM 3784 C CB  . ALA B 1 257 ? 124.451 119.998 134.402 1.00 43.22  ? 331 ALA B CB  1 
ATOM 3785 N N   . GLY B 1 258 ? 123.421 120.727 131.083 1.00 46.36  ? 332 GLY B N   1 
ATOM 3786 C CA  . GLY B 1 258 ? 123.873 120.678 129.710 1.00 50.97  ? 332 GLY B CA  1 
ATOM 3787 C C   . GLY B 1 258 ? 124.055 119.295 129.130 1.00 48.13  ? 332 GLY B C   1 
ATOM 3788 O O   . GLY B 1 258 ? 124.569 119.178 128.012 1.00 48.87  ? 332 GLY B O   1 
ATOM 3789 N N   . ALA B 1 259 ? 123.645 118.249 129.840 1.00 50.09  ? 333 ALA B N   1 
ATOM 3790 C CA  . ALA B 1 259 ? 123.835 116.893 129.351 1.00 49.13  ? 333 ALA B CA  1 
ATOM 3791 C C   . ALA B 1 259 ? 122.813 116.552 128.274 1.00 49.06  ? 333 ALA B C   1 
ATOM 3792 O O   . ALA B 1 259 ? 121.696 117.073 128.254 1.00 56.12  ? 333 ALA B O   1 
ATOM 3793 C CB  . ALA B 1 259 ? 123.730 115.891 130.499 1.00 51.15  ? 333 ALA B CB  1 
ATOM 3794 N N   . SER B 1 260 ? 123.212 115.662 127.372 1.00 49.85  ? 334 SER B N   1 
ATOM 3795 C CA  . SER B 1 260 ? 122.306 115.150 126.360 1.00 49.25  ? 334 SER B CA  1 
ATOM 3796 C C   . SER B 1 260 ? 121.322 114.169 126.986 1.00 53.21  ? 334 SER B C   1 
ATOM 3797 O O   . SER B 1 260 ? 121.520 113.672 128.097 1.00 59.69  ? 334 SER B O   1 
ATOM 3798 C CB  . SER B 1 260 ? 123.083 114.474 125.233 1.00 52.28  ? 334 SER B CB  1 
ATOM 3799 O OG  . SER B 1 260 ? 123.938 115.396 124.582 1.00 62.31  ? 334 SER B OG  1 
ATOM 3800 N N   . MET B 1 261 ? 120.249 113.890 126.256 1.00 48.69  ? 335 MET B N   1 
ATOM 3801 C CA  . MET B 1 261 ? 119.155 113.063 126.757 1.00 45.86  ? 335 MET B CA  1 
ATOM 3802 C C   . MET B 1 261 ? 119.327 111.652 126.208 1.00 42.82  ? 335 MET B C   1 
ATOM 3803 O O   . MET B 1 261 ? 119.227 111.423 125.001 1.00 58.84  ? 335 MET B O   1 
ATOM 3804 C CB  . MET B 1 261 ? 117.812 113.674 126.375 1.00 53.01  ? 335 MET B CB  1 
ATOM 3805 C CG  . MET B 1 261 ? 117.666 115.110 126.853 1.00 53.40  ? 335 MET B CG  1 
ATOM 3806 S SD  . MET B 1 261 ? 115.975 115.721 126.833 1.00 70.57  ? 335 MET B SD  1 
ATOM 3807 C CE  . MET B 1 261 ? 115.584 115.562 125.095 1.00 57.20  ? 335 MET B CE  1 
ATOM 3808 N N   . ILE B 1 262 ? 119.585 110.708 127.106 1.00 33.80  ? 336 ILE B N   1 
ATOM 3809 C CA  . ILE B 1 262 ? 119.899 109.335 126.734 1.00 41.04  ? 336 ILE B CA  1 
ATOM 3810 C C   . ILE B 1 262 ? 118.683 108.456 126.985 1.00 47.23  ? 336 ILE B C   1 
ATOM 3811 O O   . ILE B 1 262 ? 118.071 108.516 128.057 1.00 58.06  ? 336 ILE B O   1 
ATOM 3812 C CB  . ILE B 1 262 ? 121.117 108.821 127.517 1.00 51.78  ? 336 ILE B CB  1 
ATOM 3813 C CG1 . ILE B 1 262 ? 122.345 109.684 127.222 1.00 53.82  ? 336 ILE B CG1 1 
ATOM 3814 C CG2 . ILE B 1 262 ? 121.392 107.366 127.181 1.00 54.74  ? 336 ILE B CG2 1 
ATOM 3815 C CD1 . ILE B 1 262 ? 123.648 109.067 127.669 1.00 53.37  ? 336 ILE B CD1 1 
ATOM 3816 N N   . HIS B 1 263 ? 118.327 107.646 125.994 1.00 47.22  ? 337 HIS B N   1 
ATOM 3817 C CA  . HIS B 1 263 ? 117.245 106.690 126.167 1.00 47.40  ? 337 HIS B CA  1 
ATOM 3818 C C   . HIS B 1 263 ? 117.646 105.626 127.186 1.00 52.03  ? 337 HIS B C   1 
ATOM 3819 O O   . HIS B 1 263 ? 118.796 105.180 127.199 1.00 59.10  ? 337 HIS B O   1 
ATOM 3820 C CB  . HIS B 1 263 ? 116.897 106.040 124.831 1.00 50.10  ? 337 HIS B CB  1 
ATOM 3821 C CG  . HIS B 1 263 ? 115.686 105.164 124.880 1.00 54.20  ? 337 HIS B CG  1 
ATOM 3822 N ND1 . HIS B 1 263 ? 115.737 103.847 125.279 1.00 56.13  ? 337 HIS B ND1 1 
ATOM 3823 C CD2 . HIS B 1 263 ? 114.390 105.415 124.578 1.00 57.69  ? 337 HIS B CD2 1 
ATOM 3824 C CE1 . HIS B 1 263 ? 114.526 103.324 125.222 1.00 53.05  ? 337 HIS B CE1 1 
ATOM 3825 N NE2 . HIS B 1 263 ? 113.690 104.255 124.801 1.00 55.76  ? 337 HIS B NE2 1 
ATOM 3826 N N   . PRO B 1 264 ? 116.722 105.196 128.052 1.00 48.02  ? 338 PRO B N   1 
ATOM 3827 C CA  . PRO B 1 264 ? 117.089 104.271 129.135 1.00 47.74  ? 338 PRO B CA  1 
ATOM 3828 C C   . PRO B 1 264 ? 117.475 102.871 128.680 1.00 49.30  ? 338 PRO B C   1 
ATOM 3829 O O   . PRO B 1 264 ? 117.780 102.033 129.535 1.00 52.69  ? 338 PRO B O   1 
ATOM 3830 C CB  . PRO B 1 264 ? 115.823 104.238 130.004 1.00 51.19  ? 338 PRO B CB  1 
ATOM 3831 C CG  . PRO B 1 264 ? 114.731 104.643 129.101 1.00 51.37  ? 338 PRO B CG  1 
ATOM 3832 C CD  . PRO B 1 264 ? 115.326 105.647 128.169 1.00 50.05  ? 338 PRO B CD  1 
ATOM 3833 N N   . ASN B 1 265 ? 117.477 102.578 127.384 1.00 59.11  ? 339 ASN B N   1 
ATOM 3834 C CA  . ASN B 1 265 ? 117.965 101.296 126.893 1.00 59.58  ? 339 ASN B CA  1 
ATOM 3835 C C   . ASN B 1 265 ? 119.410 101.357 126.416 1.00 55.99  ? 339 ASN B C   1 
ATOM 3836 O O   . ASN B 1 265 ? 119.917 100.359 125.895 1.00 59.86  ? 339 ASN B O   1 
ATOM 3837 C CB  . ASN B 1 265 ? 117.070 100.780 125.764 1.00 58.43  ? 339 ASN B CB  1 
ATOM 3838 C CG  . ASN B 1 265 ? 115.787 100.158 126.275 1.00 63.99  ? 339 ASN B CG  1 
ATOM 3839 O OD1 . ASN B 1 265 ? 115.722 99.685  127.409 1.00 63.29  ? 339 ASN B OD1 1 
ATOM 3840 N ND2 . ASN B 1 265 ? 114.758 100.151 125.438 1.00 65.69  ? 339 ASN B ND2 1 
ATOM 3841 N N   . VAL B 1 266 ? 120.079 102.493 126.577 1.00 53.31  ? 340 VAL B N   1 
ATOM 3842 C CA  . VAL B 1 266 ? 121.489 102.632 126.226 1.00 49.35  ? 340 VAL B CA  1 
ATOM 3843 C C   . VAL B 1 266 ? 122.314 102.302 127.467 1.00 60.88  ? 340 VAL B C   1 
ATOM 3844 O O   . VAL B 1 266 ? 122.234 103.040 128.461 1.00 69.98  ? 340 VAL B O   1 
ATOM 3845 C CB  . VAL B 1 266 ? 121.804 104.045 125.723 1.00 47.84  ? 340 VAL B CB  1 
ATOM 3846 C CG1 . VAL B 1 266 ? 123.269 104.157 125.339 1.00 56.86  ? 340 VAL B CG1 1 
ATOM 3847 C CG2 . VAL B 1 266 ? 120.910 104.397 124.548 1.00 56.00  ? 340 VAL B CG2 1 
ATOM 3848 N N   . PRO B 1 267 ? 123.103 101.233 127.455 1.00 51.69  ? 341 PRO B N   1 
ATOM 3849 C CA  . PRO B 1 267 ? 123.881 100.868 128.647 1.00 47.04  ? 341 PRO B CA  1 
ATOM 3850 C C   . PRO B 1 267 ? 125.138 101.704 128.820 1.00 51.18  ? 341 PRO B C   1 
ATOM 3851 O O   . PRO B 1 267 ? 126.219 101.301 128.379 1.00 54.80  ? 341 PRO B O   1 
ATOM 3852 C CB  . PRO B 1 267 ? 124.216 99.394  128.399 1.00 47.69  ? 341 PRO B CB  1 
ATOM 3853 C CG  . PRO B 1 267 ? 124.249 99.273  126.919 1.00 45.91  ? 341 PRO B CG  1 
ATOM 3854 C CD  . PRO B 1 267 ? 123.219 100.227 126.386 1.00 47.56  ? 341 PRO B CD  1 
ATOM 3855 N N   . ALA B 1 268 ? 125.018 102.870 129.452 1.00 45.00  ? 342 ALA B N   1 
ATOM 3856 C CA  . ALA B 1 268 ? 126.158 103.760 129.594 1.00 44.46  ? 342 ALA B CA  1 
ATOM 3857 C C   . ALA B 1 268 ? 126.034 104.576 130.873 1.00 39.67  ? 342 ALA B C   1 
ATOM 3858 O O   . ALA B 1 268 ? 124.965 104.654 131.483 1.00 41.17  ? 342 ALA B O   1 
ATOM 3859 C CB  . ALA B 1 268 ? 126.285 104.679 128.379 1.00 43.33  ? 342 ALA B CB  1 
ATOM 3860 N N   . ILE B 1 269 ? 127.151 105.178 131.276 1.00 38.92  ? 343 ILE B N   1 
ATOM 3861 C CA  . ILE B 1 269 ? 127.231 106.036 132.453 1.00 37.13  ? 343 ILE B CA  1 
ATOM 3862 C C   . ILE B 1 269 ? 127.656 107.423 131.998 1.00 39.90  ? 343 ILE B C   1 
ATOM 3863 O O   . ILE B 1 269 ? 128.638 107.564 131.260 1.00 49.37  ? 343 ILE B O   1 
ATOM 3864 C CB  . ILE B 1 269 ? 128.222 105.490 133.497 1.00 33.89  ? 343 ILE B CB  1 
ATOM 3865 C CG1 . ILE B 1 269 ? 127.769 104.132 134.023 1.00 39.82  ? 343 ILE B CG1 1 
ATOM 3866 C CG2 . ILE B 1 269 ? 128.377 106.465 134.644 1.00 38.02  ? 343 ILE B CG2 1 
ATOM 3867 C CD1 . ILE B 1 269 ? 128.681 103.578 135.090 1.00 43.78  ? 343 ILE B CD1 1 
ATOM 3868 N N   . MET B 1 270 ? 126.932 108.442 132.445 1.00 31.75  ? 344 MET B N   1 
ATOM 3869 C CA  . MET B 1 270 ? 127.185 109.816 132.041 1.00 32.28  ? 344 MET B CA  1 
ATOM 3870 C C   . MET B 1 270 ? 128.008 110.543 133.093 1.00 43.47  ? 344 MET B C   1 
ATOM 3871 O O   . MET B 1 270 ? 127.838 110.320 134.294 1.00 51.33  ? 344 MET B O   1 
ATOM 3872 C CB  . MET B 1 270 ? 125.873 110.565 131.817 1.00 32.24  ? 344 MET B CB  1 
ATOM 3873 C CG  . MET B 1 270 ? 124.853 109.801 131.011 1.00 42.28  ? 344 MET B CG  1 
ATOM 3874 S SD  . MET B 1 270 ? 123.341 110.747 130.798 1.00 66.94  ? 344 MET B SD  1 
ATOM 3875 C CE  . MET B 1 270 ? 123.966 112.180 129.928 1.00 48.71  ? 344 MET B CE  1 
ATOM 3876 N N   . ILE B 1 271 ? 128.907 111.411 132.634 1.00 31.70  ? 345 ILE B N   1 
ATOM 3877 C CA  . ILE B 1 271 ? 129.643 112.326 133.498 1.00 22.89  ? 345 ILE B CA  1 
ATOM 3878 C C   . ILE B 1 271 ? 129.439 113.732 132.959 1.00 28.52  ? 345 ILE B C   1 
ATOM 3879 O O   . ILE B 1 271 ? 129.843 114.030 131.829 1.00 35.42  ? 345 ILE B O   1 
ATOM 3880 C CB  . ILE B 1 271 ? 131.140 111.987 133.571 1.00 18.93  ? 345 ILE B CB  1 
ATOM 3881 C CG1 . ILE B 1 271 ? 131.343 110.563 134.079 1.00 20.70  ? 345 ILE B CG1 1 
ATOM 3882 C CG2 . ILE B 1 271 ? 131.859 112.968 134.470 1.00 32.76  ? 345 ILE B CG2 1 
ATOM 3883 C CD1 . ILE B 1 271 ? 132.786 110.135 134.098 1.00 33.70  ? 345 ILE B CD1 1 
ATOM 3884 N N   . THR B 1 272 ? 128.817 114.591 133.760 1.00 36.01  ? 346 THR B N   1 
ATOM 3885 C CA  . THR B 1 272 ? 128.497 115.942 133.341 1.00 30.04  ? 346 THR B CA  1 
ATOM 3886 C C   . THR B 1 272 ? 128.915 116.934 134.418 1.00 41.61  ? 346 THR B C   1 
ATOM 3887 O O   . THR B 1 272 ? 128.697 116.689 135.609 1.00 49.21  ? 346 THR B O   1 
ATOM 3888 C CB  . THR B 1 272 ? 126.995 116.077 133.052 1.00 33.66  ? 346 THR B CB  1 
ATOM 3889 O OG1 . THR B 1 272 ? 126.624 115.167 132.010 1.00 43.60  ? 346 THR B OG1 1 
ATOM 3890 C CG2 . THR B 1 272 ? 126.642 117.492 132.632 1.00 34.13  ? 346 THR B CG2 1 
ATOM 3891 N N   . PRO B 1 273 ? 129.550 118.037 134.038 1.00 42.96  ? 347 PRO B N   1 
ATOM 3892 C CA  . PRO B 1 273 ? 129.888 119.071 135.016 1.00 43.66  ? 347 PRO B CA  1 
ATOM 3893 C C   . PRO B 1 273 ? 128.685 119.937 135.353 1.00 47.16  ? 347 PRO B C   1 
ATOM 3894 O O   . PRO B 1 273 ? 127.689 119.984 134.629 1.00 56.42  ? 347 PRO B O   1 
ATOM 3895 C CB  . PRO B 1 273 ? 130.960 119.893 134.299 1.00 37.80  ? 347 PRO B CB  1 
ATOM 3896 C CG  . PRO B 1 273 ? 130.618 119.737 132.864 1.00 40.40  ? 347 PRO B CG  1 
ATOM 3897 C CD  . PRO B 1 273 ? 130.105 118.336 132.709 1.00 38.99  ? 347 PRO B CD  1 
ATOM 3898 N N   . ILE B 1 274 ? 128.796 120.630 136.477 1.00 44.28  ? 348 ILE B N   1 
ATOM 3899 C CA  . ILE B 1 274 ? 127.832 121.647 136.873 1.00 45.31  ? 348 ILE B CA  1 
ATOM 3900 C C   . ILE B 1 274 ? 128.570 122.977 136.828 1.00 53.03  ? 348 ILE B C   1 
ATOM 3901 O O   . ILE B 1 274 ? 129.379 123.279 137.712 1.00 56.40  ? 348 ILE B O   1 
ATOM 3902 C CB  . ILE B 1 274 ? 127.237 121.376 138.259 1.00 48.46  ? 348 ILE B CB  1 
ATOM 3903 C CG1 . ILE B 1 274 ? 126.611 119.983 138.307 1.00 47.35  ? 348 ILE B CG1 1 
ATOM 3904 C CG2 . ILE B 1 274 ? 126.198 122.427 138.603 1.00 50.32  ? 348 ILE B CG2 1 
ATOM 3905 C CD1 . ILE B 1 274 ? 126.001 119.638 139.646 1.00 51.81  ? 348 ILE B CD1 1 
ATOM 3906 N N   . CYS B 1 275 ? 128.301 123.768 135.792 1.00 54.39  ? 349 CYS B N   1 
ATOM 3907 C CA  . CYS B 1 275 ? 128.958 125.050 135.562 1.00 51.97  ? 349 CYS B CA  1 
ATOM 3908 C C   . CYS B 1 275 ? 130.475 124.906 135.613 1.00 54.42  ? 349 CYS B C   1 
ATOM 3909 O O   . CYS B 1 275 ? 131.114 125.432 136.532 1.00 61.56  ? 349 CYS B O   1 
ATOM 3910 C CB  . CYS B 1 275 ? 128.491 126.082 136.589 1.00 56.71  ? 349 CYS B CB  1 
ATOM 3911 S SG  . CYS B 1 275 ? 126.719 126.413 136.556 1.00 58.95  ? 349 CYS B SG  1 
ATOM 3912 N N   . PRO B 1 276 ? 131.086 124.202 134.662 1.00 54.11  ? 350 PRO B N   1 
ATOM 3913 C CA  . PRO B 1 276 ? 132.544 124.070 134.673 1.00 52.45  ? 350 PRO B CA  1 
ATOM 3914 C C   . PRO B 1 276 ? 133.224 125.401 134.401 1.00 55.88  ? 350 PRO B C   1 
ATOM 3915 O O   . PRO B 1 276 ? 132.702 126.258 133.684 1.00 57.99  ? 350 PRO B O   1 
ATOM 3916 C CB  . PRO B 1 276 ? 132.816 123.067 133.549 1.00 57.92  ? 350 PRO B CB  1 
ATOM 3917 C CG  . PRO B 1 276 ? 131.682 123.258 132.614 1.00 58.36  ? 350 PRO B CG  1 
ATOM 3918 C CD  . PRO B 1 276 ? 130.488 123.583 133.467 1.00 59.13  ? 350 PRO B CD  1 
ATOM 3919 N N   . HIS B 1 277 ? 134.409 125.568 134.991 1.00 63.38  ? 351 HIS B N   1 
ATOM 3920 C CA  . HIS B 1 277 ? 135.153 126.808 134.801 1.00 64.56  ? 351 HIS B CA  1 
ATOM 3921 C C   . HIS B 1 277 ? 135.621 126.961 133.359 1.00 69.40  ? 351 HIS B C   1 
ATOM 3922 O O   . HIS B 1 277 ? 135.540 128.054 132.787 1.00 72.37  ? 351 HIS B O   1 
ATOM 3923 C CB  . HIS B 1 277 ? 136.341 126.859 135.759 1.00 65.85  ? 351 HIS B CB  1 
ATOM 3924 C CG  . HIS B 1 277 ? 137.137 128.123 135.666 1.00 74.20  ? 351 HIS B CG  1 
ATOM 3925 N ND1 . HIS B 1 277 ? 136.638 129.346 136.058 1.00 74.25  ? 351 HIS B ND1 1 
ATOM 3926 C CD2 . HIS B 1 277 ? 138.396 128.353 135.225 1.00 74.25  ? 351 HIS B CD2 1 
ATOM 3927 C CE1 . HIS B 1 277 ? 137.556 130.276 135.863 1.00 75.63  ? 351 HIS B CE1 1 
ATOM 3928 N NE2 . HIS B 1 277 ? 138.632 129.700 135.358 1.00 73.63  ? 351 HIS B NE2 1 
ATOM 3929 N N   . SER B 1 278 ? 136.111 125.881 132.756 1.00 65.16  ? 352 SER B N   1 
ATOM 3930 C CA  . SER B 1 278 ? 136.592 125.944 131.384 1.00 62.34  ? 352 SER B CA  1 
ATOM 3931 C C   . SER B 1 278 ? 135.427 126.044 130.408 1.00 60.12  ? 352 SER B C   1 
ATOM 3932 O O   . SER B 1 278 ? 134.378 125.424 130.601 1.00 64.97  ? 352 SER B O   1 
ATOM 3933 C CB  . SER B 1 278 ? 137.438 124.716 131.062 1.00 64.63  ? 352 SER B CB  1 
ATOM 3934 O OG  . SER B 1 278 ? 136.671 123.533 131.174 1.00 62.39  ? 352 SER B OG  1 
ATOM 3935 N N   . LEU B 1 279 ? 135.619 126.835 129.351 1.00 58.26  ? 353 LEU B N   1 
ATOM 3936 C CA  . LEU B 1 279 ? 134.575 126.983 128.344 1.00 61.88  ? 353 LEU B CA  1 
ATOM 3937 C C   . LEU B 1 279 ? 134.377 125.700 127.549 1.00 61.54  ? 353 LEU B C   1 
ATOM 3938 O O   . LEU B 1 279 ? 133.252 125.388 127.146 1.00 62.21  ? 353 LEU B O   1 
ATOM 3939 C CB  . LEU B 1 279 ? 134.908 128.144 127.409 1.00 63.29  ? 353 LEU B CB  1 
ATOM 3940 C CG  . LEU B 1 279 ? 134.949 129.533 128.049 1.00 66.84  ? 353 LEU B CG  1 
ATOM 3941 C CD1 . LEU B 1 279 ? 135.061 130.610 126.983 1.00 63.51  ? 353 LEU B CD1 1 
ATOM 3942 C CD2 . LEU B 1 279 ? 133.722 129.763 128.915 1.00 64.40  ? 353 LEU B CD2 1 
ATOM 3943 N N   . SER B 1 280 ? 135.448 124.948 127.315 1.00 60.59  ? 354 SER B N   1 
ATOM 3944 C CA  . SER B 1 280 ? 135.383 123.675 126.604 1.00 62.07  ? 354 SER B CA  1 
ATOM 3945 C C   . SER B 1 280 ? 135.534 122.555 127.620 1.00 62.12  ? 354 SER B C   1 
ATOM 3946 O O   . SER B 1 280 ? 136.652 122.135 127.925 1.00 61.92  ? 354 SER B O   1 
ATOM 3947 C CB  . SER B 1 280 ? 136.466 123.574 125.536 1.00 61.13  ? 354 SER B CB  1 
ATOM 3948 O OG  . SER B 1 280 ? 137.758 123.607 126.117 1.00 62.50  ? 354 SER B OG  1 
ATOM 3949 N N   . PHE B 1 281 ? 134.411 122.092 128.163 1.00 59.22  ? 355 PHE B N   1 
ATOM 3950 C CA  . PHE B 1 281 ? 134.405 120.845 128.926 1.00 57.42  ? 355 PHE B CA  1 
ATOM 3951 C C   . PHE B 1 281 ? 133.024 120.226 128.712 1.00 52.85  ? 355 PHE B C   1 
ATOM 3952 O O   . PHE B 1 281 ? 132.082 120.496 129.459 1.00 56.16  ? 355 PHE B O   1 
ATOM 3953 C CB  . PHE B 1 281 ? 134.710 121.089 130.396 1.00 53.82  ? 355 PHE B CB  1 
ATOM 3954 C CG  . PHE B 1 281 ? 134.843 119.835 131.207 1.00 59.25  ? 355 PHE B CG  1 
ATOM 3955 C CD1 . PHE B 1 281 ? 135.973 119.042 131.097 1.00 59.73  ? 355 PHE B CD1 1 
ATOM 3956 C CD2 . PHE B 1 281 ? 133.855 119.459 132.093 1.00 61.27  ? 355 PHE B CD2 1 
ATOM 3957 C CE1 . PHE B 1 281 ? 136.102 117.889 131.847 1.00 61.36  ? 355 PHE B CE1 1 
ATOM 3958 C CE2 . PHE B 1 281 ? 133.977 118.308 132.846 1.00 60.12  ? 355 PHE B CE2 1 
ATOM 3959 C CZ  . PHE B 1 281 ? 135.101 117.522 132.724 1.00 61.83  ? 355 PHE B CZ  1 
ATOM 3960 N N   . ARG B 1 282 ? 132.926 119.393 127.693 1.00 51.21  ? 356 ARG B N   1 
ATOM 3961 C CA  . ARG B 1 282 ? 131.661 118.813 127.274 1.00 50.71  ? 356 ARG B CA  1 
ATOM 3962 C C   . ARG B 1 282 ? 131.308 117.630 128.172 1.00 56.92  ? 356 ARG B C   1 
ATOM 3963 O O   . ARG B 1 282 ? 132.203 116.927 128.650 1.00 62.77  ? 356 ARG B O   1 
ATOM 3964 C CB  . ARG B 1 282 ? 131.749 118.357 125.816 1.00 54.71  ? 356 ARG B CB  1 
ATOM 3965 C CG  . ARG B 1 282 ? 130.421 118.249 125.082 1.00 60.95  ? 356 ARG B CG  1 
ATOM 3966 C CD  . ARG B 1 282 ? 129.679 119.575 125.044 1.00 59.83  ? 356 ARG B CD  1 
ATOM 3967 N NE  . ARG B 1 282 ? 130.504 120.665 124.540 1.00 57.10  ? 356 ARG B NE  1 
ATOM 3968 C CZ  . ARG B 1 282 ? 130.510 121.080 123.281 1.00 60.47  ? 356 ARG B CZ  1 
ATOM 3969 N NH1 . ARG B 1 282 ? 129.758 120.503 122.359 1.00 59.54  ? 356 ARG B NH1 1 
ATOM 3970 N NH2 . ARG B 1 282 ? 131.287 122.103 122.939 1.00 59.64  ? 356 ARG B NH2 1 
ATOM 3971 N N   . PRO B 1 283 ? 130.023 117.398 128.436 1.00 35.13  ? 357 PRO B N   1 
ATOM 3972 C CA  . PRO B 1 283 ? 129.636 116.180 129.151 1.00 35.09  ? 357 PRO B CA  1 
ATOM 3973 C C   . PRO B 1 283 ? 130.057 114.944 128.374 1.00 34.25  ? 357 PRO B C   1 
ATOM 3974 O O   . PRO B 1 283 ? 129.983 114.906 127.144 1.00 44.30  ? 357 PRO B O   1 
ATOM 3975 C CB  . PRO B 1 283 ? 128.112 116.296 129.247 1.00 33.88  ? 357 PRO B CB  1 
ATOM 3976 C CG  . PRO B 1 283 ? 127.851 117.754 129.188 1.00 34.99  ? 357 PRO B CG  1 
ATOM 3977 C CD  . PRO B 1 283 ? 128.887 118.319 128.266 1.00 37.94  ? 357 PRO B CD  1 
ATOM 3978 N N   . ILE B 1 284 ? 130.508 113.930 129.102 1.00 19.03  ? 358 ILE B N   1 
ATOM 3979 C CA  . ILE B 1 284 ? 130.974 112.694 128.493 1.00 25.62  ? 358 ILE B CA  1 
ATOM 3980 C C   . ILE B 1 284 ? 130.129 111.545 129.016 1.00 33.49  ? 358 ILE B C   1 
ATOM 3981 O O   . ILE B 1 284 ? 129.598 111.593 130.130 1.00 40.29  ? 358 ILE B O   1 
ATOM 3982 C CB  . ILE B 1 284 ? 132.470 112.435 128.771 1.00 30.34  ? 358 ILE B CB  1 
ATOM 3983 C CG1 . ILE B 1 284 ? 132.715 112.265 130.266 1.00 27.19  ? 358 ILE B CG1 1 
ATOM 3984 C CG2 . ILE B 1 284 ? 133.313 113.573 128.236 1.00 36.40  ? 358 ILE B CG2 1 
ATOM 3985 C CD1 . ILE B 1 284 ? 134.103 111.782 130.600 1.00 33.99  ? 358 ILE B CD1 1 
ATOM 3986 N N   . VAL B 1 285 ? 130.000 110.507 128.197 1.00 40.36  ? 359 VAL B N   1 
ATOM 3987 C CA  . VAL B 1 285 ? 129.317 109.284 128.589 1.00 29.31  ? 359 VAL B CA  1 
ATOM 3988 C C   . VAL B 1 285 ? 130.254 108.114 128.314 1.00 31.46  ? 359 VAL B C   1 
ATOM 3989 O O   . VAL B 1 285 ? 130.919 108.064 127.274 1.00 47.42  ? 359 VAL B O   1 
ATOM 3990 C CB  . VAL B 1 285 ? 127.963 109.124 127.865 1.00 17.97  ? 359 VAL B CB  1 
ATOM 3991 C CG1 . VAL B 1 285 ? 128.149 108.913 126.391 1.00 29.43  ? 359 VAL B CG1 1 
ATOM 3992 C CG2 . VAL B 1 285 ? 127.158 108.008 128.481 1.00 35.42  ? 359 VAL B CG2 1 
ATOM 3993 N N   . VAL B 1 286 ? 130.336 107.198 129.267 1.00 24.76  ? 360 VAL B N   1 
ATOM 3994 C CA  . VAL B 1 286 ? 131.356 106.153 129.269 1.00 17.42  ? 360 VAL B CA  1 
ATOM 3995 C C   . VAL B 1 286 ? 130.642 104.810 129.276 1.00 27.28  ? 360 VAL B C   1 
ATOM 3996 O O   . VAL B 1 286 ? 129.439 104.735 129.578 1.00 44.11  ? 360 VAL B O   1 
ATOM 3997 C CB  . VAL B 1 286 ? 132.322 106.303 130.467 1.00 31.07  ? 360 VAL B CB  1 
ATOM 3998 C CG1 . VAL B 1 286 ? 133.085 107.605 130.366 1.00 31.32  ? 360 VAL B CG1 1 
ATOM 3999 C CG2 . VAL B 1 286 ? 131.559 106.232 131.775 1.00 42.56  ? 360 VAL B CG2 1 
ATOM 4000 N N   . PRO B 1 287 ? 131.342 103.725 128.934 1.00 17.85  ? 361 PRO B N   1 
ATOM 4001 C CA  . PRO B 1 287 ? 130.699 102.406 128.945 1.00 26.28  ? 361 PRO B CA  1 
ATOM 4002 C C   . PRO B 1 287 ? 130.173 102.045 130.326 1.00 40.63  ? 361 PRO B C   1 
ATOM 4003 O O   . PRO B 1 287 ? 130.687 102.496 131.351 1.00 45.62  ? 361 PRO B O   1 
ATOM 4004 C CB  . PRO B 1 287 ? 131.822 101.461 128.509 1.00 26.10  ? 361 PRO B CB  1 
ATOM 4005 C CG  . PRO B 1 287 ? 132.734 102.312 127.726 1.00 32.45  ? 361 PRO B CG  1 
ATOM 4006 C CD  . PRO B 1 287 ? 132.702 103.657 128.372 1.00 25.53  ? 361 PRO B CD  1 
ATOM 4007 N N   . ALA B 1 288 ? 129.119 101.226 130.337 1.00 36.65  ? 362 ALA B N   1 
ATOM 4008 C CA  . ALA B 1 288 ? 128.417 100.933 131.582 1.00 29.99  ? 362 ALA B CA  1 
ATOM 4009 C C   . ALA B 1 288 ? 129.301 100.184 132.571 1.00 38.42  ? 362 ALA B C   1 
ATOM 4010 O O   . ALA B 1 288 ? 129.270 100.461 133.775 1.00 42.61  ? 362 ALA B O   1 
ATOM 4011 C CB  . ALA B 1 288 ? 127.150 100.131 131.292 1.00 40.11  ? 362 ALA B CB  1 
ATOM 4012 N N   . GLY B 1 289 ? 130.097 99.236  132.087 1.00 46.00  ? 363 GLY B N   1 
ATOM 4013 C CA  . GLY B 1 289 ? 130.827 98.352  132.974 1.00 47.52  ? 363 GLY B CA  1 
ATOM 4014 C C   . GLY B 1 289 ? 132.150 98.895  133.470 1.00 52.11  ? 363 GLY B C   1 
ATOM 4015 O O   . GLY B 1 289 ? 133.021 98.125  133.885 1.00 56.70  ? 363 GLY B O   1 
ATOM 4016 N N   . VAL B 1 290 ? 132.319 100.208 133.434 1.00 50.25  ? 364 VAL B N   1 
ATOM 4017 C CA  . VAL B 1 290 ? 133.576 100.821 133.830 1.00 47.81  ? 364 VAL B CA  1 
ATOM 4018 C C   . VAL B 1 290 ? 133.512 101.154 135.317 1.00 53.03  ? 364 VAL B C   1 
ATOM 4019 O O   . VAL B 1 290 ? 132.439 101.201 135.923 1.00 53.87  ? 364 VAL B O   1 
ATOM 4020 C CB  . VAL B 1 290 ? 133.876 102.072 132.979 1.00 47.84  ? 364 VAL B CB  1 
ATOM 4021 C CG1 . VAL B 1 290 ? 132.960 103.222 133.362 1.00 49.25  ? 364 VAL B CG1 1 
ATOM 4022 C CG2 . VAL B 1 290 ? 135.346 102.441 133.039 1.00 55.36  ? 364 VAL B CG2 1 
ATOM 4023 N N   . GLU B 1 291 ? 134.678 101.382 135.917 1.00 57.37  ? 365 GLU B N   1 
ATOM 4024 C CA  . GLU B 1 291 ? 134.804 101.652 137.347 1.00 54.92  ? 365 GLU B CA  1 
ATOM 4025 C C   . GLU B 1 291 ? 135.190 103.115 137.543 1.00 53.75  ? 365 GLU B C   1 
ATOM 4026 O O   . GLU B 1 291 ? 136.302 103.521 137.193 1.00 56.82  ? 365 GLU B O   1 
ATOM 4027 C CB  . GLU B 1 291 ? 135.837 100.719 137.978 1.00 55.55  ? 365 GLU B CB  1 
ATOM 4028 C CG  . GLU B 1 291 ? 135.698 100.524 139.480 1.00 61.34  ? 365 GLU B CG  1 
ATOM 4029 C CD  . GLU B 1 291 ? 136.226 101.696 140.283 1.00 65.82  ? 365 GLU B CD  1 
ATOM 4030 O OE1 . GLU B 1 291 ? 137.130 102.401 139.788 1.00 63.02  ? 365 GLU B OE1 1 
ATOM 4031 O OE2 . GLU B 1 291 ? 135.740 101.909 141.414 1.00 65.24  ? 365 GLU B OE2 1 
ATOM 4032 N N   . LEU B 1 292 ? 134.270 103.900 138.097 1.00 47.37  ? 366 LEU B N   1 
ATOM 4033 C CA  . LEU B 1 292 ? 134.531 105.285 138.460 1.00 48.04  ? 366 LEU B CA  1 
ATOM 4034 C C   . LEU B 1 292 ? 135.132 105.373 139.856 1.00 54.10  ? 366 LEU B C   1 
ATOM 4035 O O   . LEU B 1 292 ? 134.919 104.501 140.702 1.00 61.48  ? 366 LEU B O   1 
ATOM 4036 C CB  . LEU B 1 292 ? 133.246 106.112 138.408 1.00 43.59  ? 366 LEU B CB  1 
ATOM 4037 C CG  . LEU B 1 292 ? 132.608 106.417 137.059 1.00 50.13  ? 366 LEU B CG  1 
ATOM 4038 C CD1 . LEU B 1 292 ? 131.245 107.036 137.260 1.00 60.45  ? 366 LEU B CD1 1 
ATOM 4039 C CD2 . LEU B 1 292 ? 133.487 107.394 136.340 1.00 55.25  ? 366 LEU B CD2 1 
ATOM 4040 N N   . LYS B 1 293 ? 135.878 106.448 140.093 1.00 47.10  ? 367 LYS B N   1 
ATOM 4041 C CA  . LYS B 1 293 ? 136.452 106.714 141.408 1.00 43.29  ? 367 LYS B CA  1 
ATOM 4042 C C   . LYS B 1 293 ? 136.759 108.199 141.498 1.00 47.80  ? 367 LYS B C   1 
ATOM 4043 O O   . LYS B 1 293 ? 137.668 108.686 140.819 1.00 55.82  ? 367 LYS B O   1 
ATOM 4044 C CB  . LYS B 1 293 ? 137.712 105.883 141.640 1.00 46.29  ? 367 LYS B CB  1 
ATOM 4045 C CG  . LYS B 1 293 ? 138.274 105.984 143.044 1.00 46.12  ? 367 LYS B CG  1 
ATOM 4046 C CD  . LYS B 1 293 ? 139.468 105.064 143.212 1.00 49.15  ? 367 LYS B CD  1 
ATOM 4047 C CE  . LYS B 1 293 ? 140.033 105.138 144.619 1.00 53.96  ? 367 LYS B CE  1 
ATOM 4048 N NZ  . LYS B 1 293 ? 140.460 106.519 144.974 1.00 55.68  ? 367 LYS B NZ  1 
ATOM 4049 N N   . ILE B 1 294 ? 136.010 108.912 142.334 1.00 40.05  ? 368 ILE B N   1 
ATOM 4050 C CA  . ILE B 1 294 ? 136.118 110.359 142.470 1.00 39.87  ? 368 ILE B CA  1 
ATOM 4051 C C   . ILE B 1 294 ? 136.645 110.668 143.864 1.00 49.72  ? 368 ILE B C   1 
ATOM 4052 O O   . ILE B 1 294 ? 136.148 110.123 144.856 1.00 55.26  ? 368 ILE B O   1 
ATOM 4053 C CB  . ILE B 1 294 ? 134.764 111.050 142.225 1.00 29.05  ? 368 ILE B CB  1 
ATOM 4054 C CG1 . ILE B 1 294 ? 134.305 110.836 140.786 1.00 37.06  ? 368 ILE B CG1 1 
ATOM 4055 C CG2 . ILE B 1 294 ? 134.852 112.526 142.529 1.00 39.22  ? 368 ILE B CG2 1 
ATOM 4056 C CD1 . ILE B 1 294 ? 133.004 111.525 140.464 1.00 45.14  ? 368 ILE B CD1 1 
ATOM 4057 N N   . MET B 1 295 ? 137.658 111.528 143.939 1.00 56.19  ? 369 MET B N   1 
ATOM 4058 C CA  . MET B 1 295 ? 138.256 111.888 145.215 1.00 45.46  ? 369 MET B CA  1 
ATOM 4059 C C   . MET B 1 295 ? 138.835 113.289 145.118 1.00 47.12  ? 369 MET B C   1 
ATOM 4060 O O   . MET B 1 295 ? 139.185 113.764 144.035 1.00 53.74  ? 369 MET B O   1 
ATOM 4061 C CB  . MET B 1 295 ? 139.339 110.887 145.629 1.00 52.67  ? 369 MET B CB  1 
ATOM 4062 C CG  . MET B 1 295 ? 140.452 110.725 144.607 1.00 60.11  ? 369 MET B CG  1 
ATOM 4063 S SD  . MET B 1 295 ? 141.600 109.401 145.024 1.00 67.05  ? 369 MET B SD  1 
ATOM 4064 C CE  . MET B 1 295 ? 142.146 109.928 146.645 1.00 53.91  ? 369 MET B CE  1 
ATOM 4065 N N   . LEU B 1 296 ? 138.944 113.944 146.270 1.00 47.55  ? 370 LEU B N   1 
ATOM 4066 C CA  . LEU B 1 296 ? 139.425 115.316 146.307 1.00 53.29  ? 370 LEU B CA  1 
ATOM 4067 C C   . LEU B 1 296 ? 140.897 115.395 145.925 1.00 62.75  ? 370 LEU B C   1 
ATOM 4068 O O   . LEU B 1 296 ? 141.693 114.503 146.229 1.00 71.46  ? 370 LEU B O   1 
ATOM 4069 C CB  . LEU B 1 296 ? 139.223 115.921 147.695 1.00 52.98  ? 370 LEU B CB  1 
ATOM 4070 C CG  . LEU B 1 296 ? 137.782 116.171 148.131 1.00 58.59  ? 370 LEU B CG  1 
ATOM 4071 C CD1 . LEU B 1 296 ? 137.754 116.745 149.535 1.00 58.36  ? 370 LEU B CD1 1 
ATOM 4072 C CD2 . LEU B 1 296 ? 137.088 117.103 147.155 1.00 64.36  ? 370 LEU B CD2 1 
ATOM 4073 N N   . SER B 1 297 ? 141.250 116.481 145.245 1.00 62.38  ? 371 SER B N   1 
ATOM 4074 C CA  . SER B 1 297 ? 142.635 116.713 144.882 1.00 60.71  ? 371 SER B CA  1 
ATOM 4075 C C   . SER B 1 297 ? 143.463 117.015 146.129 1.00 65.98  ? 371 SER B C   1 
ATOM 4076 O O   . SER B 1 297 ? 142.955 117.588 147.097 1.00 67.58  ? 371 SER B O   1 
ATOM 4077 C CB  . SER B 1 297 ? 142.740 117.871 143.895 1.00 64.86  ? 371 SER B CB  1 
ATOM 4078 O OG  . SER B 1 297 ? 142.270 119.076 144.473 1.00 67.76  ? 371 SER B OG  1 
ATOM 4079 N N   . PRO B 1 298 ? 144.738 116.623 146.138 1.00 66.03  ? 372 PRO B N   1 
ATOM 4080 C CA  . PRO B 1 298 ? 145.588 116.939 147.297 1.00 62.76  ? 372 PRO B CA  1 
ATOM 4081 C C   . PRO B 1 298 ? 145.723 118.429 147.555 1.00 61.88  ? 372 PRO B C   1 
ATOM 4082 O O   . PRO B 1 298 ? 145.897 118.837 148.709 1.00 65.21  ? 372 PRO B O   1 
ATOM 4083 C CB  . PRO B 1 298 ? 146.934 116.302 146.926 1.00 68.51  ? 372 PRO B CB  1 
ATOM 4084 C CG  . PRO B 1 298 ? 146.591 115.244 145.929 1.00 69.45  ? 372 PRO B CG  1 
ATOM 4085 C CD  . PRO B 1 298 ? 145.437 115.788 145.148 1.00 66.02  ? 372 PRO B CD  1 
ATOM 4086 N N   . GLU B 1 299 ? 145.650 119.250 146.514 1.00 74.76  ? 373 GLU B N   1 
ATOM 4087 C CA  . GLU B 1 299 ? 145.706 120.696 146.636 1.00 79.70  ? 373 GLU B CA  1 
ATOM 4088 C C   . GLU B 1 299 ? 144.280 121.236 146.769 1.00 79.90  ? 373 GLU B C   1 
ATOM 4089 O O   . GLU B 1 299 ? 143.299 120.505 146.615 1.00 80.42  ? 373 GLU B O   1 
ATOM 4090 C CB  . GLU B 1 299 ? 146.452 121.283 145.430 1.00 80.90  ? 373 GLU B CB  1 
ATOM 4091 C CG  . GLU B 1 299 ? 146.714 122.785 145.465 1.00 82.85  ? 373 GLU B CG  1 
ATOM 4092 C CD  . GLU B 1 299 ? 147.657 123.189 146.583 1.00 84.23  ? 373 GLU B CD  1 
ATOM 4093 O OE1 . GLU B 1 299 ? 148.475 122.346 147.009 1.00 85.34  ? 373 GLU B OE1 1 
ATOM 4094 O OE2 . GLU B 1 299 ? 147.580 124.350 147.037 1.00 83.03  ? 373 GLU B OE2 1 
ATOM 4095 N N   . ALA B 1 300 ? 144.167 122.533 147.071 1.00 65.30  ? 374 ALA B N   1 
ATOM 4096 C CA  . ALA B 1 300 ? 142.883 123.218 147.226 1.00 62.37  ? 374 ALA B CA  1 
ATOM 4097 C C   . ALA B 1 300 ? 142.050 122.558 148.330 1.00 64.28  ? 374 ALA B C   1 
ATOM 4098 O O   . ALA B 1 300 ? 140.980 121.992 148.103 1.00 62.01  ? 374 ALA B O   1 
ATOM 4099 C CB  . ALA B 1 300 ? 142.116 123.262 145.899 1.00 66.73  ? 374 ALA B CB  1 
ATOM 4100 N N   . ARG B 1 301 ? 142.588 122.650 149.545 1.00 76.88  ? 375 ARG B N   1 
ATOM 4101 C CA  . ARG B 1 301 ? 141.995 121.984 150.697 1.00 80.83  ? 375 ARG B CA  1 
ATOM 4102 C C   . ARG B 1 301 ? 140.686 122.641 151.118 1.00 81.44  ? 375 ARG B C   1 
ATOM 4103 O O   . ARG B 1 301 ? 140.681 123.585 151.916 1.00 84.07  ? 375 ARG B O   1 
ATOM 4104 C CB  . ARG B 1 301 ? 142.977 121.978 151.871 1.00 80.74  ? 375 ARG B CB  1 
ATOM 4105 C CG  . ARG B 1 301 ? 144.188 121.084 151.661 1.00 80.20  ? 375 ARG B CG  1 
ATOM 4106 C CD  . ARG B 1 301 ? 144.998 120.829 152.922 1.00 83.32  ? 375 ARG B CD  1 
ATOM 4107 N NE  . ARG B 1 301 ? 145.574 122.057 153.462 1.00 84.41  ? 375 ARG B NE  1 
ATOM 4108 C CZ  . ARG B 1 301 ? 146.732 122.569 153.074 1.00 82.32  ? 375 ARG B CZ  1 
ATOM 4109 N NH1 . ARG B 1 301 ? 147.447 121.963 152.134 1.00 80.28  ? 375 ARG B NH1 1 
ATOM 4110 N NH2 . ARG B 1 301 ? 147.181 123.692 153.621 1.00 81.83  ? 375 ARG B NH2 1 
ATOM 4111 N N   . ASN B 1 302 ? 139.574 122.141 150.587 1.00 72.91  ? 376 ASN B N   1 
ATOM 4112 C CA  . ASN B 1 302 ? 138.243 122.539 151.034 1.00 68.93  ? 376 ASN B CA  1 
ATOM 4113 C C   . ASN B 1 302 ? 137.284 121.385 150.780 1.00 65.01  ? 376 ASN B C   1 
ATOM 4114 O O   . ASN B 1 302 ? 137.297 120.785 149.702 1.00 69.33  ? 376 ASN B O   1 
ATOM 4115 C CB  . ASN B 1 302 ? 137.776 123.834 150.350 1.00 68.93  ? 376 ASN B CB  1 
ATOM 4116 C CG  . ASN B 1 302 ? 137.807 123.760 148.828 1.00 75.50  ? 376 ASN B CG  1 
ATOM 4117 O OD1 . ASN B 1 302 ? 138.120 122.729 148.238 1.00 74.62  ? 376 ASN B OD1 1 
ATOM 4118 N ND2 . ASN B 1 302 ? 137.478 124.875 148.187 1.00 76.77  ? 376 ASN B ND2 1 
ATOM 4119 N N   . THR B 1 303 ? 136.483 121.053 151.786 1.00 53.05  ? 377 THR B N   1 
ATOM 4120 C CA  . THR B 1 303 ? 135.651 119.863 151.713 1.00 53.54  ? 377 THR B CA  1 
ATOM 4121 C C   . THR B 1 303 ? 134.545 120.026 150.679 1.00 61.15  ? 377 THR B C   1 
ATOM 4122 O O   . THR B 1 303 ? 134.007 121.119 150.484 1.00 67.40  ? 377 THR B O   1 
ATOM 4123 C CB  . THR B 1 303 ? 135.044 119.557 153.080 1.00 60.36  ? 377 THR B CB  1 
ATOM 4124 O OG1 . THR B 1 303 ? 134.217 120.652 153.494 1.00 62.52  ? 377 THR B OG1 1 
ATOM 4125 C CG2 . THR B 1 303 ? 136.140 119.336 154.110 1.00 62.38  ? 377 THR B CG2 1 
ATOM 4126 N N   . ALA B 1 304 ? 134.216 118.927 150.009 1.00 63.11  ? 378 ALA B N   1 
ATOM 4127 C CA  . ALA B 1 304 ? 133.093 118.847 149.089 1.00 59.90  ? 378 ALA B CA  1 
ATOM 4128 C C   . ALA B 1 304 ? 132.004 117.971 149.691 1.00 54.11  ? 378 ALA B C   1 
ATOM 4129 O O   . ALA B 1 304 ? 132.215 117.265 150.680 1.00 60.55  ? 378 ALA B O   1 
ATOM 4130 C CB  . ALA B 1 304 ? 133.537 118.299 147.728 1.00 58.45  ? 378 ALA B CB  1 
ATOM 4131 N N   . TRP B 1 305 ? 130.823 118.022 149.085 1.00 44.30  ? 379 TRP B N   1 
ATOM 4132 C CA  . TRP B 1 305 ? 129.674 117.282 149.581 1.00 52.05  ? 379 TRP B CA  1 
ATOM 4133 C C   . TRP B 1 305 ? 129.103 116.404 148.479 1.00 55.51  ? 379 TRP B C   1 
ATOM 4134 O O   . TRP B 1 305 ? 129.160 116.746 147.296 1.00 66.15  ? 379 TRP B O   1 
ATOM 4135 C CB  . TRP B 1 305 ? 128.592 118.223 150.120 1.00 58.44  ? 379 TRP B CB  1 
ATOM 4136 C CG  . TRP B 1 305 ? 129.079 119.125 151.213 1.00 60.86  ? 379 TRP B CG  1 
ATOM 4137 C CD1 . TRP B 1 305 ? 129.804 120.267 151.069 1.00 56.23  ? 379 TRP B CD1 1 
ATOM 4138 C CD2 . TRP B 1 305 ? 128.886 118.946 152.620 1.00 50.57  ? 379 TRP B CD2 1 
ATOM 4139 N NE1 . TRP B 1 305 ? 130.066 120.819 152.298 1.00 55.66  ? 379 TRP B NE1 1 
ATOM 4140 C CE2 . TRP B 1 305 ? 129.513 120.025 153.267 1.00 48.31  ? 379 TRP B CE2 1 
ATOM 4141 C CE3 . TRP B 1 305 ? 128.238 117.981 153.395 1.00 47.27  ? 379 TRP B CE3 1 
ATOM 4142 C CZ2 . TRP B 1 305 ? 129.514 120.166 154.650 1.00 53.98  ? 379 TRP B CZ2 1 
ATOM 4143 C CZ3 . TRP B 1 305 ? 128.239 118.123 154.767 1.00 54.61  ? 379 TRP B CZ3 1 
ATOM 4144 C CH2 . TRP B 1 305 ? 128.874 119.206 155.381 1.00 58.14  ? 379 TRP B CH2 1 
ATOM 4145 N N   . VAL B 1 306 ? 128.548 115.265 148.884 1.00 32.99  ? 380 VAL B N   1 
ATOM 4146 C CA  . VAL B 1 306 ? 128.015 114.268 147.966 1.00 22.43  ? 380 VAL B CA  1 
ATOM 4147 C C   . VAL B 1 306 ? 126.547 114.031 148.289 1.00 34.96  ? 380 VAL B C   1 
ATOM 4148 O O   . VAL B 1 306 ? 126.166 113.936 149.460 1.00 51.51  ? 380 VAL B O   1 
ATOM 4149 C CB  . VAL B 1 306 ? 128.815 112.951 148.031 1.00 29.09  ? 380 VAL B CB  1 
ATOM 4150 C CG1 . VAL B 1 306 ? 128.833 112.396 149.443 1.00 36.53  ? 380 VAL B CG1 1 
ATOM 4151 C CG2 . VAL B 1 306 ? 128.234 111.934 147.073 1.00 40.33  ? 380 VAL B CG2 1 
ATOM 4152 N N   . SER B 1 307 ? 125.721 113.953 147.248 1.00 39.24  ? 381 SER B N   1 
ATOM 4153 C CA  . SER B 1 307 ? 124.301 113.682 147.392 1.00 42.71  ? 381 SER B CA  1 
ATOM 4154 C C   . SER B 1 307 ? 123.910 112.512 146.503 1.00 43.59  ? 381 SER B C   1 
ATOM 4155 O O   . SER B 1 307 ? 124.436 112.347 145.400 1.00 53.10  ? 381 SER B O   1 
ATOM 4156 C CB  . SER B 1 307 ? 123.457 114.909 147.039 1.00 47.53  ? 381 SER B CB  1 
ATOM 4157 O OG  . SER B 1 307 ? 123.672 115.304 145.696 1.00 48.94  ? 381 SER B OG  1 
ATOM 4158 N N   . PHE B 1 308 ? 122.975 111.702 146.992 1.00 40.04  ? 382 PHE B N   1 
ATOM 4159 C CA  . PHE B 1 308 ? 122.476 110.526 146.282 1.00 45.06  ? 382 PHE B CA  1 
ATOM 4160 C C   . PHE B 1 308 ? 120.979 110.709 146.055 1.00 48.07  ? 382 PHE B C   1 
ATOM 4161 O O   . PHE B 1 308 ? 120.169 110.347 146.909 1.00 51.68  ? 382 PHE B O   1 
ATOM 4162 C CB  . PHE B 1 308 ? 122.762 109.255 147.062 1.00 44.57  ? 382 PHE B CB  1 
ATOM 4163 C CG  . PHE B 1 308 ? 124.168 109.159 147.574 1.00 45.70  ? 382 PHE B CG  1 
ATOM 4164 C CD1 . PHE B 1 308 ? 125.164 108.608 146.791 1.00 41.68  ? 382 PHE B CD1 1 
ATOM 4165 C CD2 . PHE B 1 308 ? 124.492 109.614 148.838 1.00 48.05  ? 382 PHE B CD2 1 
ATOM 4166 C CE1 . PHE B 1 308 ? 126.454 108.516 147.258 1.00 44.75  ? 382 PHE B CE1 1 
ATOM 4167 C CE2 . PHE B 1 308 ? 125.783 109.524 149.308 1.00 49.35  ? 382 PHE B CE2 1 
ATOM 4168 C CZ  . PHE B 1 308 ? 126.764 108.974 148.517 1.00 50.98  ? 382 PHE B CZ  1 
ATOM 4169 N N   . ASP B 1 309 ? 120.618 111.264 144.897 1.00 51.00  ? 383 ASP B N   1 
ATOM 4170 C CA  . ASP B 1 309 ? 119.220 111.521 144.546 1.00 51.81  ? 383 ASP B CA  1 
ATOM 4171 C C   . ASP B 1 309 ? 118.547 112.433 145.570 1.00 59.80  ? 383 ASP B C   1 
ATOM 4172 O O   . ASP B 1 309 ? 117.365 112.281 145.880 1.00 63.31  ? 383 ASP B O   1 
ATOM 4173 C CB  . ASP B 1 309 ? 118.435 110.217 144.392 1.00 56.34  ? 383 ASP B CB  1 
ATOM 4174 C CG  . ASP B 1 309 ? 118.949 109.356 143.261 1.00 61.85  ? 383 ASP B CG  1 
ATOM 4175 O OD1 . ASP B 1 309 ? 119.409 109.917 142.246 1.00 61.09  ? 383 ASP B OD1 1 
ATOM 4176 O OD2 . ASP B 1 309 ? 118.886 108.116 143.387 1.00 65.82  ? 383 ASP B OD2 1 
ATOM 4177 N N   . GLY B 1 310 ? 119.304 113.390 146.098 1.00 49.90  ? 384 GLY B N   1 
ATOM 4178 C CA  . GLY B 1 310 ? 118.777 114.291 147.101 1.00 47.40  ? 384 GLY B CA  1 
ATOM 4179 C C   . GLY B 1 310 ? 118.723 113.730 148.502 1.00 50.90  ? 384 GLY B C   1 
ATOM 4180 O O   . GLY B 1 310 ? 118.203 114.401 149.400 1.00 56.45  ? 384 GLY B O   1 
ATOM 4181 N N   . ARG B 1 311 ? 119.246 112.526 148.721 1.00 48.69  ? 385 ARG B N   1 
ATOM 4182 C CA  . ARG B 1 311 ? 119.257 111.909 150.041 1.00 45.38  ? 385 ARG B CA  1 
ATOM 4183 C C   . ARG B 1 311 ? 120.393 112.474 150.881 1.00 48.45  ? 385 ARG B C   1 
ATOM 4184 O O   . ARG B 1 311 ? 120.953 113.522 150.544 1.00 55.70  ? 385 ARG B O   1 
ATOM 4185 C CB  . ARG B 1 311 ? 119.373 110.389 149.925 1.00 45.20  ? 385 ARG B CB  1 
ATOM 4186 C CG  . ARG B 1 311 ? 118.149 109.727 149.313 1.00 51.72  ? 385 ARG B CG  1 
ATOM 4187 C CD  . ARG B 1 311 ? 118.415 108.266 148.997 1.00 51.39  ? 385 ARG B CD  1 
ATOM 4188 N NE  . ARG B 1 311 ? 118.492 107.443 150.197 1.00 53.22  ? 385 ARG B NE  1 
ATOM 4189 C CZ  . ARG B 1 311 ? 118.616 106.123 150.189 1.00 53.97  ? 385 ARG B CZ  1 
ATOM 4190 N NH1 . ARG B 1 311 ? 118.693 105.444 149.057 1.00 54.81  ? 385 ARG B NH1 1 
ATOM 4191 N NH2 . ARG B 1 311 ? 118.669 105.469 151.346 1.00 50.23  ? 385 ARG B NH2 1 
ATOM 4192 N N   . LYS B 1 312 ? 120.712 111.800 151.986 1.00 48.33  ? 386 LYS B N   1 
ATOM 4193 C CA  . LYS B 1 312 ? 121.655 112.305 152.980 1.00 54.54  ? 386 LYS B CA  1 
ATOM 4194 C C   . LYS B 1 312 ? 122.930 112.830 152.336 1.00 58.53  ? 386 LYS B C   1 
ATOM 4195 O O   . LYS B 1 312 ? 123.644 112.092 151.652 1.00 63.92  ? 386 LYS B O   1 
ATOM 4196 C CB  . LYS B 1 312 ? 121.993 111.198 153.982 1.00 58.66  ? 386 LYS B CB  1 
ATOM 4197 C CG  . LYS B 1 312 ? 121.006 111.053 155.134 1.00 56.85  ? 386 LYS B CG  1 
ATOM 4198 C CD  . LYS B 1 312 ? 119.703 110.412 154.684 1.00 62.53  ? 386 LYS B CD  1 
ATOM 4199 C CE  . LYS B 1 312 ? 119.906 108.948 154.334 1.00 64.44  ? 386 LYS B CE  1 
ATOM 4200 N NZ  . LYS B 1 312 ? 118.629 108.285 153.953 1.00 61.38  ? 386 LYS B NZ  1 
ATOM 4201 N N   . ARG B 1 313 ? 123.212 114.111 152.564 1.00 46.03  ? 387 ARG B N   1 
ATOM 4202 C CA  . ARG B 1 313 ? 124.413 114.733 152.030 1.00 32.71  ? 387 ARG B CA  1 
ATOM 4203 C C   . ARG B 1 313 ? 125.570 114.556 152.999 1.00 39.88  ? 387 ARG B C   1 
ATOM 4204 O O   . ARG B 1 313 ? 125.529 115.050 154.129 1.00 53.28  ? 387 ARG B O   1 
ATOM 4205 C CB  . ARG B 1 313 ? 124.180 116.217 151.762 1.00 34.09  ? 387 ARG B CB  1 
ATOM 4206 C CG  . ARG B 1 313 ? 122.904 116.517 151.020 1.00 38.49  ? 387 ARG B CG  1 
ATOM 4207 C CD  . ARG B 1 313 ? 122.455 117.944 151.260 1.00 41.39  ? 387 ARG B CD  1 
ATOM 4208 N NE  . ARG B 1 313 ? 123.277 118.901 150.529 1.00 41.84  ? 387 ARG B NE  1 
ATOM 4209 C CZ  . ARG B 1 313 ? 124.263 119.607 151.062 1.00 45.21  ? 387 ARG B CZ  1 
ATOM 4210 N NH1 . ARG B 1 313 ? 124.564 119.515 152.346 1.00 48.33  ? 387 ARG B NH1 1 
ATOM 4211 N NH2 . ARG B 1 313 ? 124.964 120.430 150.287 1.00 41.71  ? 387 ARG B NH2 1 
ATOM 4212 N N   . GLN B 1 314 ? 126.604 113.861 152.551 1.00 38.12  ? 388 GLN B N   1 
ATOM 4213 C CA  . GLN B 1 314 ? 127.795 113.625 153.347 1.00 49.39  ? 388 GLN B CA  1 
ATOM 4214 C C   . GLN B 1 314 ? 128.883 114.614 152.950 1.00 58.19  ? 388 GLN B C   1 
ATOM 4215 O O   . GLN B 1 314 ? 128.805 115.284 151.920 1.00 62.36  ? 388 GLN B O   1 
ATOM 4216 C CB  . GLN B 1 314 ? 128.282 112.186 153.161 1.00 51.35  ? 388 GLN B CB  1 
ATOM 4217 C CG  . GLN B 1 314 ? 127.224 111.138 153.444 1.00 50.63  ? 388 GLN B CG  1 
ATOM 4218 C CD  . GLN B 1 314 ? 127.751 109.729 153.296 1.00 51.50  ? 388 GLN B CD  1 
ATOM 4219 O OE1 . GLN B 1 314 ? 126.984 108.769 153.248 1.00 53.50  ? 388 GLN B OE1 1 
ATOM 4220 N NE2 . GLN B 1 314 ? 129.068 109.597 153.221 1.00 58.38  ? 388 GLN B NE2 1 
ATOM 4221 N N   . GLU B 1 315 ? 129.911 114.698 153.787 1.00 54.17  ? 389 GLU B N   1 
ATOM 4222 C CA  . GLU B 1 315 ? 131.067 115.543 153.526 1.00 54.53  ? 389 GLU B CA  1 
ATOM 4223 C C   . GLU B 1 315 ? 132.269 114.656 153.249 1.00 56.85  ? 389 GLU B C   1 
ATOM 4224 O O   . GLU B 1 315 ? 132.581 113.764 154.044 1.00 57.95  ? 389 GLU B O   1 
ATOM 4225 C CB  . GLU B 1 315 ? 131.352 116.474 154.705 1.00 56.91  ? 389 GLU B CB  1 
ATOM 4226 C CG  . GLU B 1 315 ? 132.716 117.143 154.652 1.00 63.23  ? 389 GLU B CG  1 
ATOM 4227 C CD  . GLU B 1 315 ? 132.955 118.076 155.823 1.00 67.41  ? 389 GLU B CD  1 
ATOM 4228 O OE1 . GLU B 1 315 ? 132.109 118.964 156.060 1.00 67.20  ? 389 GLU B OE1 1 
ATOM 4229 O OE2 . GLU B 1 315 ? 133.989 117.923 156.507 1.00 66.80  ? 389 GLU B OE2 1 
ATOM 4230 N N   . ILE B 1 316 ? 132.936 114.896 152.125 1.00 49.98  ? 390 ILE B N   1 
ATOM 4231 C CA  . ILE B 1 316 ? 134.126 114.146 151.745 1.00 50.38  ? 390 ILE B CA  1 
ATOM 4232 C C   . ILE B 1 316 ? 135.353 115.002 152.027 1.00 65.12  ? 390 ILE B C   1 
ATOM 4233 O O   . ILE B 1 316 ? 135.406 116.180 151.651 1.00 68.02  ? 390 ILE B O   1 
ATOM 4234 C CB  . ILE B 1 316 ? 134.066 113.701 150.272 1.00 50.58  ? 390 ILE B CB  1 
ATOM 4235 C CG1 . ILE B 1 316 ? 134.004 114.900 149.325 1.00 56.24  ? 390 ILE B CG1 1 
ATOM 4236 C CG2 . ILE B 1 316 ? 132.874 112.789 150.043 1.00 60.07  ? 390 ILE B CG2 1 
ATOM 4237 C CD1 . ILE B 1 316 ? 134.177 114.533 147.869 1.00 60.56  ? 390 ILE B CD1 1 
ATOM 4238 N N   . ARG B 1 317 ? 136.314 114.425 152.737 1.00 65.96  ? 391 ARG B N   1 
ATOM 4239 C CA  . ARG B 1 317 ? 137.570 115.070 153.069 1.00 54.96  ? 391 ARG B CA  1 
ATOM 4240 C C   . ARG B 1 317 ? 138.679 114.512 152.178 1.00 62.14  ? 391 ARG B C   1 
ATOM 4241 O O   . ARG B 1 317 ? 138.425 113.782 151.215 1.00 66.38  ? 391 ARG B O   1 
ATOM 4242 C CB  . ARG B 1 317 ? 137.863 114.893 154.558 1.00 50.26  ? 391 ARG B CB  1 
ATOM 4243 C CG  . ARG B 1 317 ? 137.010 115.783 155.446 1.00 56.10  ? 391 ARG B CG  1 
ATOM 4244 C CD  . ARG B 1 317 ? 137.102 115.377 156.903 1.00 58.44  ? 391 ARG B CD  1 
ATOM 4245 N NE  . ARG B 1 317 ? 136.438 114.103 157.147 1.00 55.52  ? 391 ARG B NE  1 
ATOM 4246 C CZ  . ARG B 1 317 ? 135.150 113.973 157.433 1.00 58.51  ? 391 ARG B CZ  1 
ATOM 4247 N NH1 . ARG B 1 317 ? 134.351 115.025 157.515 1.00 56.06  ? 391 ARG B NH1 1 
ATOM 4248 N NH2 . ARG B 1 317 ? 134.649 112.759 157.639 1.00 61.04  ? 391 ARG B NH2 1 
ATOM 4249 N N   . HIS B 1 318 ? 139.926 114.866 152.494 1.00 65.30  ? 392 HIS B N   1 
ATOM 4250 C CA  . HIS B 1 318 ? 141.060 114.472 151.667 1.00 66.74  ? 392 HIS B CA  1 
ATOM 4251 C C   . HIS B 1 318 ? 141.248 112.964 151.577 1.00 69.10  ? 392 HIS B C   1 
ATOM 4252 O O   . HIS B 1 318 ? 141.844 112.492 150.602 1.00 77.36  ? 392 HIS B O   1 
ATOM 4253 C CB  . HIS B 1 318 ? 142.339 115.109 152.207 1.00 68.74  ? 392 HIS B CB  1 
ATOM 4254 C CG  . HIS B 1 318 ? 142.369 116.598 152.085 1.00 74.37  ? 392 HIS B CG  1 
ATOM 4255 N ND1 . HIS B 1 318 ? 141.865 117.435 153.056 1.00 76.95  ? 392 HIS B ND1 1 
ATOM 4256 C CD2 . HIS B 1 318 ? 142.847 117.403 151.106 1.00 77.32  ? 392 HIS B CD2 1 
ATOM 4257 C CE1 . HIS B 1 318 ? 142.028 118.691 152.681 1.00 76.80  ? 392 HIS B CE1 1 
ATOM 4258 N NE2 . HIS B 1 318 ? 142.622 118.699 151.501 1.00 78.13  ? 392 HIS B NE2 1 
ATOM 4259 N N   . GLY B 1 319 ? 140.767 112.200 152.552 1.00 55.37  ? 393 GLY B N   1 
ATOM 4260 C CA  . GLY B 1 319 ? 140.996 110.769 152.558 1.00 56.26  ? 393 GLY B CA  1 
ATOM 4261 C C   . GLY B 1 319 ? 139.805 109.939 152.130 1.00 56.40  ? 393 GLY B C   1 
ATOM 4262 O O   . GLY B 1 319 ? 139.866 108.707 152.138 1.00 58.08  ? 393 GLY B O   1 
ATOM 4263 N N   . ASP B 1 320 ? 138.715 110.598 151.754 1.00 57.81  ? 394 ASP B N   1 
ATOM 4264 C CA  . ASP B 1 320 ? 137.491 109.905 151.382 1.00 54.21  ? 394 ASP B CA  1 
ATOM 4265 C C   . ASP B 1 320 ? 137.427 109.696 149.875 1.00 57.60  ? 394 ASP B C   1 
ATOM 4266 O O   . ASP B 1 320 ? 137.758 110.593 149.095 1.00 65.07  ? 394 ASP B O   1 
ATOM 4267 C CB  . ASP B 1 320 ? 136.267 110.690 151.857 1.00 59.97  ? 394 ASP B CB  1 
ATOM 4268 C CG  . ASP B 1 320 ? 136.353 111.065 153.322 1.00 64.99  ? 394 ASP B CG  1 
ATOM 4269 O OD1 . ASP B 1 320 ? 137.005 110.323 154.086 1.00 65.49  ? 394 ASP B OD1 1 
ATOM 4270 O OD2 . ASP B 1 320 ? 135.769 112.098 153.711 1.00 67.72  ? 394 ASP B OD2 1 
ATOM 4271 N N   . SER B 1 321 ? 136.996 108.503 149.474 1.00 48.83  ? 395 SER B N   1 
ATOM 4272 C CA  . SER B 1 321 ? 136.885 108.138 148.072 1.00 51.43  ? 395 SER B CA  1 
ATOM 4273 C C   . SER B 1 321 ? 135.503 107.569 147.795 1.00 51.47  ? 395 SER B C   1 
ATOM 4274 O O   . SER B 1 321 ? 134.944 106.828 148.607 1.00 53.05  ? 395 SER B O   1 
ATOM 4275 C CB  . SER B 1 321 ? 137.953 107.115 147.672 1.00 56.63  ? 395 SER B CB  1 
ATOM 4276 O OG  . SER B 1 321 ? 137.827 106.761 146.307 1.00 59.15  ? 395 SER B OG  1 
ATOM 4277 N N   . ILE B 1 322 ? 134.958 107.922 146.635 1.00 47.90  ? 396 ILE B N   1 
ATOM 4278 C CA  . ILE B 1 322 ? 133.658 107.442 146.187 1.00 45.48  ? 396 ILE B CA  1 
ATOM 4279 C C   . ILE B 1 322 ? 133.857 106.671 144.888 1.00 46.94  ? 396 ILE B C   1 
ATOM 4280 O O   . ILE B 1 322 ? 134.539 107.147 143.974 1.00 52.88  ? 396 ILE B O   1 
ATOM 4281 C CB  . ILE B 1 322 ? 132.651 108.602 146.029 1.00 38.53  ? 396 ILE B CB  1 
ATOM 4282 C CG1 . ILE B 1 322 ? 131.246 108.077 145.761 1.00 53.18  ? 396 ILE B CG1 1 
ATOM 4283 C CG2 . ILE B 1 322 ? 133.060 109.580 144.957 1.00 43.94  ? 396 ILE B CG2 1 
ATOM 4284 C CD1 . ILE B 1 322 ? 130.185 109.137 145.900 1.00 54.74  ? 396 ILE B CD1 1 
ATOM 4285 N N   . SER B 1 323 ? 133.304 105.461 144.827 1.00 46.69  ? 397 SER B N   1 
ATOM 4286 C CA  . SER B 1 323 ? 133.458 104.577 143.679 1.00 49.14  ? 397 SER B CA  1 
ATOM 4287 C C   . SER B 1 323 ? 132.092 104.268 143.086 1.00 52.97  ? 397 SER B C   1 
ATOM 4288 O O   . SER B 1 323 ? 131.159 103.918 143.817 1.00 55.77  ? 397 SER B O   1 
ATOM 4289 C CB  . SER B 1 323 ? 134.168 103.281 144.069 1.00 55.52  ? 397 SER B CB  1 
ATOM 4290 O OG  . SER B 1 323 ? 133.445 102.585 145.068 1.00 62.45  ? 397 SER B OG  1 
ATOM 4291 N N   . ILE B 1 324 ? 131.978 104.391 141.765 1.00 47.17  ? 398 ILE B N   1 
ATOM 4292 C CA  . ILE B 1 324 ? 130.708 104.258 141.062 1.00 41.43  ? 398 ILE B CA  1 
ATOM 4293 C C   . ILE B 1 324 ? 130.855 103.200 139.979 1.00 46.95  ? 398 ILE B C   1 
ATOM 4294 O O   . ILE B 1 324 ? 131.734 103.311 139.115 1.00 54.14  ? 398 ILE B O   1 
ATOM 4295 C CB  . ILE B 1 324 ? 130.254 105.589 140.446 1.00 39.69  ? 398 ILE B CB  1 
ATOM 4296 C CG1 . ILE B 1 324 ? 130.434 106.733 141.440 1.00 49.62  ? 398 ILE B CG1 1 
ATOM 4297 C CG2 . ILE B 1 324 ? 128.810 105.498 140.003 1.00 54.36  ? 398 ILE B CG2 1 
ATOM 4298 C CD1 . ILE B 1 324 ? 130.102 108.083 140.867 1.00 50.82  ? 398 ILE B CD1 1 
ATOM 4299 N N   . THR B 1 325 ? 129.997 102.183 140.021 1.00 48.92  ? 399 THR B N   1 
ATOM 4300 C CA  . THR B 1 325 ? 129.908 101.175 138.975 1.00 51.30  ? 399 THR B CA  1 
ATOM 4301 C C   . THR B 1 325 ? 128.440 100.863 138.726 1.00 47.59  ? 399 THR B C   1 
ATOM 4302 O O   . THR B 1 325 ? 127.580 101.119 139.572 1.00 50.55  ? 399 THR B O   1 
ATOM 4303 C CB  . THR B 1 325 ? 130.657 99.882  139.334 1.00 58.82  ? 399 THR B CB  1 
ATOM 4304 O OG1 . THR B 1 325 ? 130.099 99.315  140.524 1.00 60.44  ? 399 THR B OG1 1 
ATOM 4305 C CG2 . THR B 1 325 ? 132.136 100.145 139.548 1.00 57.36  ? 399 THR B CG2 1 
ATOM 4306 N N   . THR B 1 326 ? 128.157 100.307 137.552 1.00 45.09  ? 400 THR B N   1 
ATOM 4307 C CA  . THR B 1 326 ? 126.786 99.950  137.216 1.00 49.23  ? 400 THR B CA  1 
ATOM 4308 C C   . THR B 1 326 ? 126.344 98.742  138.032 1.00 56.41  ? 400 THR B C   1 
ATOM 4309 O O   . THR B 1 326 ? 127.048 97.729  138.094 1.00 56.70  ? 400 THR B O   1 
ATOM 4310 C CB  . THR B 1 326 ? 126.658 99.656  135.723 1.00 42.91  ? 400 THR B CB  1 
ATOM 4311 O OG1 . THR B 1 326 ? 127.033 100.816 134.973 1.00 49.98  ? 400 THR B OG1 1 
ATOM 4312 C CG2 . THR B 1 326 ? 125.229 99.282  135.375 1.00 43.96  ? 400 THR B CG2 1 
ATOM 4313 N N   . SER B 1 327 ? 125.177 98.852  138.658 1.00 57.54  ? 401 SER B N   1 
ATOM 4314 C CA  . SER B 1 327 ? 124.660 97.789  139.503 1.00 50.30  ? 401 SER B CA  1 
ATOM 4315 C C   . SER B 1 327 ? 124.124 96.636  138.662 1.00 53.03  ? 401 SER B C   1 
ATOM 4316 O O   . SER B 1 327 ? 123.763 96.794  137.493 1.00 53.56  ? 401 SER B O   1 
ATOM 4317 C CB  . SER B 1 327 ? 123.560 98.319  140.422 1.00 53.56  ? 401 SER B CB  1 
ATOM 4318 O OG  . SER B 1 327 ? 123.057 97.293  141.259 1.00 59.39  ? 401 SER B OG  1 
ATOM 4319 N N   . THR B 1 328 ? 124.079 95.458  139.279 1.00 61.78  ? 402 THR B N   1 
ATOM 4320 C CA  . THR B 1 328 ? 123.548 94.258  138.652 1.00 60.89  ? 402 THR B CA  1 
ATOM 4321 C C   . THR B 1 328 ? 122.079 94.029  138.979 1.00 61.14  ? 402 THR B C   1 
ATOM 4322 O O   . THR B 1 328 ? 121.522 92.999  138.586 1.00 59.92  ? 402 THR B O   1 
ATOM 4323 C CB  . THR B 1 328 ? 124.367 93.037  139.073 1.00 66.10  ? 402 THR B CB  1 
ATOM 4324 O OG1 . THR B 1 328 ? 124.338 92.910  140.499 1.00 64.82  ? 402 THR B OG1 1 
ATOM 4325 C CG2 . THR B 1 328 ? 125.808 93.179  138.610 1.00 64.05  ? 402 THR B CG2 1 
ATOM 4326 N N   . TYR B 1 329 ? 121.442 94.964  139.685 1.00 61.94  ? 403 TYR B N   1 
ATOM 4327 C CA  . TYR B 1 329 ? 120.036 94.868  140.071 1.00 60.79  ? 403 TYR B CA  1 
ATOM 4328 C C   . TYR B 1 329 ? 119.293 96.043  139.450 1.00 66.72  ? 403 TYR B C   1 
ATOM 4329 O O   . TYR B 1 329 ? 119.177 97.114  140.068 1.00 68.60  ? 403 TYR B O   1 
ATOM 4330 C CB  . TYR B 1 329 ? 119.883 94.864  141.590 1.00 56.70  ? 403 TYR B CB  1 
ATOM 4331 C CG  . TYR B 1 329 ? 120.676 93.784  142.285 1.00 58.97  ? 403 TYR B CG  1 
ATOM 4332 C CD1 . TYR B 1 329 ? 120.213 92.476  142.329 1.00 64.39  ? 403 TYR B CD1 1 
ATOM 4333 C CD2 . TYR B 1 329 ? 121.885 94.072  142.899 1.00 63.17  ? 403 TYR B CD2 1 
ATOM 4334 C CE1 . TYR B 1 329 ? 120.935 91.486  142.964 1.00 65.43  ? 403 TYR B CE1 1 
ATOM 4335 C CE2 . TYR B 1 329 ? 122.614 93.089  143.536 1.00 68.28  ? 403 TYR B CE2 1 
ATOM 4336 C CZ  . TYR B 1 329 ? 122.135 91.797  143.566 1.00 67.00  ? 403 TYR B CZ  1 
ATOM 4337 O OH  . TYR B 1 329 ? 122.859 90.815  144.200 1.00 64.05  ? 403 TYR B OH  1 
ATOM 4338 N N   . PRO B 1 330 ? 118.775 95.893  138.235 1.00 55.84  ? 404 PRO B N   1 
ATOM 4339 C CA  . PRO B 1 330 ? 118.087 97.008  137.579 1.00 52.16  ? 404 PRO B CA  1 
ATOM 4340 C C   . PRO B 1 330 ? 116.696 97.225  138.156 1.00 59.62  ? 404 PRO B C   1 
ATOM 4341 O O   . PRO B 1 330 ? 116.163 96.412  138.913 1.00 62.96  ? 404 PRO B O   1 
ATOM 4342 C CB  . PRO B 1 330 ? 118.024 96.566  136.117 1.00 49.93  ? 404 PRO B CB  1 
ATOM 4343 C CG  . PRO B 1 330 ? 118.006 95.083  136.189 1.00 48.59  ? 404 PRO B CG  1 
ATOM 4344 C CD  . PRO B 1 330 ? 118.861 94.707  137.366 1.00 49.81  ? 404 PRO B CD  1 
ATOM 4345 N N   . LEU B 1 331 ? 116.104 98.360  137.778 1.00 60.67  ? 405 LEU B N   1 
ATOM 4346 C CA  . LEU B 1 331 ? 114.753 98.700  138.195 1.00 52.57  ? 405 LEU B CA  1 
ATOM 4347 C C   . LEU B 1 331 ? 113.802 98.502  137.026 1.00 61.02  ? 405 LEU B C   1 
ATOM 4348 O O   . LEU B 1 331 ? 113.848 99.286  136.066 1.00 67.98  ? 405 LEU B O   1 
ATOM 4349 C CB  . LEU B 1 331 ? 114.689 100.141 138.695 1.00 52.78  ? 405 LEU B CB  1 
ATOM 4350 C CG  . LEU B 1 331 ? 113.331 100.656 139.173 1.00 58.63  ? 405 LEU B CG  1 
ATOM 4351 C CD1 . LEU B 1 331 ? 113.498 101.473 140.438 1.00 59.86  ? 405 LEU B CD1 1 
ATOM 4352 C CD2 . LEU B 1 331 ? 112.656 101.494 138.101 1.00 59.56  ? 405 LEU B CD2 1 
ATOM 4353 N N   . PRO B 1 332 ? 112.944 97.486  137.045 1.00 56.26  ? 406 PRO B N   1 
ATOM 4354 C CA  . PRO B 1 332 ? 111.979 97.297  135.955 1.00 53.22  ? 406 PRO B CA  1 
ATOM 4355 C C   . PRO B 1 332 ? 110.771 98.205  136.125 1.00 56.44  ? 406 PRO B C   1 
ATOM 4356 O O   . PRO B 1 332 ? 109.956 98.021  137.034 1.00 58.44  ? 406 PRO B O   1 
ATOM 4357 C CB  . PRO B 1 332 ? 111.606 95.813  136.078 1.00 52.32  ? 406 PRO B CB  1 
ATOM 4358 C CG  . PRO B 1 332 ? 111.829 95.484  137.502 1.00 49.15  ? 406 PRO B CG  1 
ATOM 4359 C CD  . PRO B 1 332 ? 112.947 96.358  137.992 1.00 55.22  ? 406 PRO B CD  1 
ATOM 4360 N N   . SER B 1 333 ? 110.655 99.194  135.245 1.00 63.74  ? 407 SER B N   1 
ATOM 4361 C CA  . SER B 1 333 ? 109.504 100.086 135.210 1.00 65.16  ? 407 SER B CA  1 
ATOM 4362 C C   . SER B 1 333 ? 108.633 99.702  134.023 1.00 70.48  ? 407 SER B C   1 
ATOM 4363 O O   . SER B 1 333 ? 109.126 99.600  132.894 1.00 73.16  ? 407 SER B O   1 
ATOM 4364 C CB  . SER B 1 333 ? 109.939 101.547 135.110 1.00 69.22  ? 407 SER B CB  1 
ATOM 4365 O OG  . SER B 1 333 ? 108.815 102.410 135.094 1.00 66.34  ? 407 SER B OG  1 
ATOM 4366 N N   . ILE B 1 334 ? 107.347 99.492  134.278 1.00 72.91  ? 408 ILE B N   1 
ATOM 4367 C CA  . ILE B 1 334 ? 106.439 98.979  133.260 1.00 73.21  ? 408 ILE B CA  1 
ATOM 4368 C C   . ILE B 1 334 ? 106.058 100.100 132.306 1.00 74.44  ? 408 ILE B C   1 
ATOM 4369 O O   . ILE B 1 334 ? 105.625 101.176 132.732 1.00 79.76  ? 408 ILE B O   1 
ATOM 4370 C CB  . ILE B 1 334 ? 105.195 98.356  133.911 1.00 74.59  ? 408 ILE B CB  1 
ATOM 4371 C CG1 . ILE B 1 334 ? 105.598 97.178  134.797 1.00 77.01  ? 408 ILE B CG1 1 
ATOM 4372 C CG2 . ILE B 1 334 ? 104.206 97.913  132.852 1.00 76.20  ? 408 ILE B CG2 1 
ATOM 4373 C CD1 . ILE B 1 334 ? 104.432 96.469  135.432 1.00 75.58  ? 408 ILE B CD1 1 
ATOM 4374 N N   . CYS B 1 335 ? 106.222 99.851  131.010 1.00 75.80  ? 409 CYS B N   1 
ATOM 4375 C CA  . CYS B 1 335 ? 105.822 100.805 129.991 1.00 77.51  ? 409 CYS B CA  1 
ATOM 4376 C C   . CYS B 1 335 ? 104.307 100.810 129.833 1.00 78.37  ? 409 CYS B C   1 
ATOM 4377 O O   . CYS B 1 335 ? 103.618 99.840  130.160 1.00 81.20  ? 409 CYS B O   1 
ATOM 4378 C CB  . CYS B 1 335 ? 106.476 100.472 128.651 1.00 82.73  ? 409 CYS B CB  1 
ATOM 4379 S SG  . CYS B 1 335 ? 108.229 100.070 128.750 1.00 92.79  ? 409 CYS B SG  1 
ATOM 4380 N N   . VAL B 1 336 ? 103.788 101.919 129.317 1.00 82.62  ? 410 VAL B N   1 
ATOM 4381 C CA  . VAL B 1 336 ? 102.357 102.023 129.054 1.00 85.07  ? 410 VAL B CA  1 
ATOM 4382 C C   . VAL B 1 336 ? 101.993 101.411 127.705 1.00 89.42  ? 410 VAL B C   1 
ATOM 4383 O O   . VAL B 1 336 ? 101.067 100.602 127.612 1.00 91.54  ? 410 VAL B O   1 
ATOM 4384 C CB  . VAL B 1 336 ? 101.892 103.494 129.179 1.00 86.30  ? 410 VAL B CB  1 
ATOM 4385 C CG1 . VAL B 1 336 ? 102.574 104.398 128.157 1.00 87.02  ? 410 VAL B CG1 1 
ATOM 4386 C CG2 . VAL B 1 336 ? 100.381 103.583 129.048 1.00 86.90  ? 410 VAL B CG2 1 
ATOM 4387 N N   . ARG B 1 337 ? 102.702 101.774 126.636 1.00 89.36  ? 411 ARG B N   1 
ATOM 4388 C CA  . ARG B 1 337 ? 102.483 101.170 125.328 1.00 85.76  ? 411 ARG B CA  1 
ATOM 4389 C C   . ARG B 1 337 ? 103.732 100.520 124.749 1.00 87.41  ? 411 ARG B C   1 
ATOM 4390 O O   . ARG B 1 337 ? 103.664 99.371  124.296 1.00 91.11  ? 411 ARG B O   1 
ATOM 4391 C CB  . ARG B 1 337 ? 101.885 102.214 124.366 1.00 84.39  ? 411 ARG B CB  1 
ATOM 4392 C CG  . ARG B 1 337 ? 102.724 103.445 124.106 1.00 86.94  ? 411 ARG B CG  1 
ATOM 4393 C CD  . ARG B 1 337 ? 101.950 104.432 123.247 1.00 90.00  ? 411 ARG B CD  1 
ATOM 4394 N NE  . ARG B 1 337 ? 102.737 105.609 122.903 1.00 92.21  ? 411 ARG B NE  1 
ATOM 4395 C CZ  . ARG B 1 337 ? 102.820 106.699 123.652 1.00 92.35  ? 411 ARG B CZ  1 
ATOM 4396 N NH1 . ARG B 1 337 ? 102.179 106.797 124.805 1.00 90.90  ? 411 ARG B NH1 1 
ATOM 4397 N NH2 . ARG B 1 337 ? 103.564 107.719 123.233 1.00 91.84  ? 411 ARG B NH2 1 
ATOM 4398 N N   . ASP B 1 338 ? 104.875 101.207 124.754 1.00 88.14  ? 412 ASP B N   1 
ATOM 4399 C CA  . ASP B 1 338 ? 106.147 100.595 124.390 1.00 88.75  ? 412 ASP B CA  1 
ATOM 4400 C C   . ASP B 1 338 ? 107.266 101.493 124.890 1.00 88.87  ? 412 ASP B C   1 
ATOM 4401 O O   . ASP B 1 338 ? 107.059 102.701 125.041 1.00 89.26  ? 412 ASP B O   1 
ATOM 4402 C CB  . ASP B 1 338 ? 106.274 100.374 122.873 1.00 90.76  ? 412 ASP B CB  1 
ATOM 4403 C CG  . ASP B 1 338 ? 105.955 101.613 122.068 1.00 95.06  ? 412 ASP B CG  1 
ATOM 4404 O OD1 . ASP B 1 338 ? 104.975 102.306 122.399 1.00 98.20  ? 412 ASP B OD1 1 
ATOM 4405 O OD2 . ASP B 1 338 ? 106.689 101.895 121.098 1.00 92.37  ? 412 ASP B OD2 1 
ATOM 4406 N N   . PRO B 1 339 ? 108.451 100.940 125.163 1.00 84.77  ? 413 PRO B N   1 
ATOM 4407 C CA  . PRO B 1 339 ? 109.521 101.758 125.756 1.00 85.12  ? 413 PRO B CA  1 
ATOM 4408 C C   . PRO B 1 339 ? 109.952 102.937 124.903 1.00 84.65  ? 413 PRO B C   1 
ATOM 4409 O O   . PRO B 1 339 ? 110.290 103.993 125.453 1.00 82.50  ? 413 PRO B O   1 
ATOM 4410 C CB  . PRO B 1 339 ? 110.670 100.754 125.937 1.00 84.53  ? 413 PRO B CB  1 
ATOM 4411 C CG  . PRO B 1 339 ? 110.311 99.582  125.086 1.00 84.45  ? 413 PRO B CG  1 
ATOM 4412 C CD  . PRO B 1 339 ? 108.826 99.520  125.100 1.00 85.43  ? 413 PRO B CD  1 
ATOM 4413 N N   . VAL B 1 340 ? 109.952 102.797 123.579 1.00 91.33  ? 414 VAL B N   1 
ATOM 4414 C CA  . VAL B 1 340 ? 110.494 103.847 122.721 1.00 94.02  ? 414 VAL B CA  1 
ATOM 4415 C C   . VAL B 1 340 ? 109.537 105.030 122.644 1.00 96.25  ? 414 VAL B C   1 
ATOM 4416 O O   . VAL B 1 340 ? 109.915 106.174 122.919 1.00 94.87  ? 414 VAL B O   1 
ATOM 4417 C CB  . VAL B 1 340 ? 110.809 103.288 121.323 1.00 91.84  ? 414 VAL B CB  1 
ATOM 4418 C CG1 . VAL B 1 340 ? 111.328 104.392 120.419 1.00 89.58  ? 414 VAL B CG1 1 
ATOM 4419 C CG2 . VAL B 1 340 ? 111.815 102.155 121.423 1.00 90.89  ? 414 VAL B CG2 1 
ATOM 4420 N N   . SER B 1 341 ? 108.281 104.770 122.276 1.00 96.08  ? 415 SER B N   1 
ATOM 4421 C CA  . SER B 1 341 ? 107.326 105.859 122.094 1.00 93.34  ? 415 SER B CA  1 
ATOM 4422 C C   . SER B 1 341 ? 107.004 106.544 123.416 1.00 91.10  ? 415 SER B C   1 
ATOM 4423 O O   . SER B 1 341 ? 106.767 107.757 123.449 1.00 92.78  ? 415 SER B O   1 
ATOM 4424 C CB  . SER B 1 341 ? 106.049 105.339 121.438 1.00 95.60  ? 415 SER B CB  1 
ATOM 4425 O OG  . SER B 1 341 ? 105.310 104.531 122.336 1.00 99.35  ? 415 SER B OG  1 
ATOM 4426 N N   . ASP B 1 342 ? 106.983 105.784 124.513 1.00 88.21  ? 416 ASP B N   1 
ATOM 4427 C CA  . ASP B 1 342 ? 106.645 106.366 125.807 1.00 92.93  ? 416 ASP B CA  1 
ATOM 4428 C C   . ASP B 1 342 ? 107.683 107.391 126.243 1.00 92.12  ? 416 ASP B C   1 
ATOM 4429 O O   . ASP B 1 342 ? 107.338 108.421 126.833 1.00 90.71  ? 416 ASP B O   1 
ATOM 4430 C CB  . ASP B 1 342 ? 106.502 105.267 126.859 1.00 91.81  ? 416 ASP B CB  1 
ATOM 4431 C CG  . ASP B 1 342 ? 106.222 105.818 128.243 1.00 94.12  ? 416 ASP B CG  1 
ATOM 4432 O OD1 . ASP B 1 342 ? 105.162 106.451 128.430 1.00 95.67  ? 416 ASP B OD1 1 
ATOM 4433 O OD2 . ASP B 1 342 ? 107.063 105.620 129.145 1.00 95.15  ? 416 ASP B OD2 1 
ATOM 4434 N N   . TRP B 1 343 ? 108.961 107.122 125.972 1.00 80.69  ? 417 TRP B N   1 
ATOM 4435 C CA  . TRP B 1 343 ? 110.009 108.059 126.366 1.00 77.43  ? 417 TRP B CA  1 
ATOM 4436 C C   . TRP B 1 343 ? 109.899 109.371 125.601 1.00 78.02  ? 417 TRP B C   1 
ATOM 4437 O O   . TRP B 1 343 ? 110.090 110.448 126.177 1.00 80.10  ? 417 TRP B O   1 
ATOM 4438 C CB  . TRP B 1 343 ? 111.384 107.429 126.160 1.00 75.26  ? 417 TRP B CB  1 
ATOM 4439 C CG  . TRP B 1 343 ? 112.505 108.316 126.591 1.00 75.87  ? 417 TRP B CG  1 
ATOM 4440 C CD1 . TRP B 1 343 ? 112.846 108.637 127.869 1.00 75.68  ? 417 TRP B CD1 1 
ATOM 4441 C CD2 . TRP B 1 343 ? 113.449 108.979 125.745 1.00 77.24  ? 417 TRP B CD2 1 
ATOM 4442 N NE1 . TRP B 1 343 ? 113.935 109.471 127.873 1.00 75.23  ? 417 TRP B NE1 1 
ATOM 4443 C CE2 . TRP B 1 343 ? 114.326 109.694 126.579 1.00 75.88  ? 417 TRP B CE2 1 
ATOM 4444 C CE3 . TRP B 1 343 ? 113.635 109.040 124.362 1.00 76.56  ? 417 TRP B CE3 1 
ATOM 4445 C CZ2 . TRP B 1 343 ? 115.371 110.461 126.079 1.00 73.78  ? 417 TRP B CZ2 1 
ATOM 4446 C CZ3 . TRP B 1 343 ? 114.674 109.800 123.867 1.00 73.06  ? 417 TRP B CZ3 1 
ATOM 4447 C CH2 . TRP B 1 343 ? 115.529 110.501 124.723 1.00 70.76  ? 417 TRP B CH2 1 
ATOM 4448 N N   . PHE B 1 344 ? 109.596 109.304 124.305 1.00 89.29  ? 418 PHE B N   1 
ATOM 4449 C CA  . PHE B 1 344 ? 109.471 110.526 123.518 1.00 89.36  ? 418 PHE B CA  1 
ATOM 4450 C C   . PHE B 1 344 ? 108.221 111.307 123.888 1.00 90.19  ? 418 PHE B C   1 
ATOM 4451 O O   . PHE B 1 344 ? 108.223 112.541 123.826 1.00 90.46  ? 418 PHE B O   1 
ATOM 4452 C CB  . PHE B 1 344 ? 109.481 110.191 122.030 1.00 88.49  ? 418 PHE B CB  1 
ATOM 4453 C CG  . PHE B 1 344 ? 110.831 109.800 121.516 1.00 90.14  ? 418 PHE B CG  1 
ATOM 4454 C CD1 . PHE B 1 344 ? 111.770 110.763 121.203 1.00 90.29  ? 418 PHE B CD1 1 
ATOM 4455 C CD2 . PHE B 1 344 ? 111.173 108.469 121.374 1.00 90.97  ? 418 PHE B CD2 1 
ATOM 4456 C CE1 . PHE B 1 344 ? 113.017 110.407 120.739 1.00 90.75  ? 418 PHE B CE1 1 
ATOM 4457 C CE2 . PHE B 1 344 ? 112.419 108.108 120.914 1.00 91.08  ? 418 PHE B CE2 1 
ATOM 4458 C CZ  . PHE B 1 344 ? 113.342 109.078 120.595 1.00 89.99  ? 418 PHE B CZ  1 
ATOM 4459 N N   . GLU B 1 345 ? 107.146 110.613 124.266 1.00 88.60  ? 419 GLU B N   1 
ATOM 4460 C CA  . GLU B 1 345 ? 105.956 111.305 124.745 1.00 82.91  ? 419 GLU B CA  1 
ATOM 4461 C C   . GLU B 1 345 ? 106.252 112.074 126.024 1.00 83.49  ? 419 GLU B C   1 
ATOM 4462 O O   . GLU B 1 345 ? 105.754 113.188 126.219 1.00 87.26  ? 419 GLU B O   1 
ATOM 4463 C CB  . GLU B 1 345 ? 104.822 110.305 124.966 1.00 83.20  ? 419 GLU B CB  1 
ATOM 4464 C CG  . GLU B 1 345 ? 103.541 110.924 125.494 1.00 88.26  ? 419 GLU B CG  1 
ATOM 4465 C CD  . GLU B 1 345 ? 102.581 109.892 126.050 1.00 89.87  ? 419 GLU B CD  1 
ATOM 4466 O OE1 . GLU B 1 345 ? 103.028 108.766 126.354 1.00 88.32  ? 419 GLU B OE1 1 
ATOM 4467 O OE2 . GLU B 1 345 ? 101.380 110.206 126.185 1.00 91.47  ? 419 GLU B OE2 1 
ATOM 4468 N N   . SER B 1 346 ? 107.071 111.498 126.905 1.00 85.76  ? 420 SER B N   1 
ATOM 4469 C CA  . SER B 1 346 ? 107.407 112.174 128.151 1.00 88.23  ? 420 SER B CA  1 
ATOM 4470 C C   . SER B 1 346 ? 108.263 113.411 127.910 1.00 91.45  ? 420 SER B C   1 
ATOM 4471 O O   . SER B 1 346 ? 108.182 114.376 128.679 1.00 94.20  ? 420 SER B O   1 
ATOM 4472 C CB  . SER B 1 346 ? 108.122 111.210 129.094 1.00 90.92  ? 420 SER B CB  1 
ATOM 4473 O OG  . SER B 1 346 ? 108.141 111.721 130.414 1.00 95.22  ? 420 SER B OG  1 
ATOM 4474 N N   . LEU B 1 347 ? 109.086 113.402 126.861 1.00 85.91  ? 421 LEU B N   1 
ATOM 4475 C CA  . LEU B 1 347 ? 109.918 114.563 126.563 1.00 83.95  ? 421 LEU B CA  1 
ATOM 4476 C C   . LEU B 1 347 ? 109.073 115.765 126.159 1.00 84.75  ? 421 LEU B C   1 
ATOM 4477 O O   . LEU B 1 347 ? 109.398 116.905 126.508 1.00 86.66  ? 421 LEU B O   1 
ATOM 4478 C CB  . LEU B 1 347 ? 110.919 114.223 125.461 1.00 84.09  ? 421 LEU B CB  1 
ATOM 4479 C CG  . LEU B 1 347 ? 112.030 113.238 125.817 1.00 82.87  ? 421 LEU B CG  1 
ATOM 4480 C CD1 . LEU B 1 347 ? 112.833 112.881 124.582 1.00 83.77  ? 421 LEU B CD1 1 
ATOM 4481 C CD2 . LEU B 1 347 ? 112.928 113.821 126.885 1.00 85.32  ? 421 LEU B CD2 1 
ATOM 4482 N N   . ALA B 1 348 ? 107.991 115.530 125.416 1.00 90.94  ? 422 ALA B N   1 
ATOM 4483 C CA  . ALA B 1 348 ? 107.174 116.635 124.927 1.00 92.68  ? 422 ALA B CA  1 
ATOM 4484 C C   . ALA B 1 348 ? 106.462 117.358 126.064 1.00 93.95  ? 422 ALA B C   1 
ATOM 4485 O O   . ALA B 1 348 ? 106.341 118.588 126.043 1.00 94.87  ? 422 ALA B O   1 
ATOM 4486 C CB  . ALA B 1 348 ? 106.164 116.122 123.901 1.00 92.00  ? 422 ALA B CB  1 
ATOM 4487 N N   . GLN B 1 349 ? 105.978 116.618 127.062 1.00 102.03 ? 423 GLN B N   1 
ATOM 4488 C CA  . GLN B 1 349 ? 105.163 117.226 128.109 1.00 103.07 ? 423 GLN B CA  1 
ATOM 4489 C C   . GLN B 1 349 ? 105.975 117.714 129.303 1.00 103.46 ? 423 GLN B C   1 
ATOM 4490 O O   . GLN B 1 349 ? 105.608 118.718 129.923 1.00 103.53 ? 423 GLN B O   1 
ATOM 4491 C CB  . GLN B 1 349 ? 104.090 116.243 128.587 1.00 103.37 ? 423 GLN B CB  1 
ATOM 4492 C CG  . GLN B 1 349 ? 102.916 116.070 127.630 1.00 104.36 ? 423 GLN B CG  1 
ATOM 4493 C CD  . GLN B 1 349 ? 103.283 115.325 126.364 1.00 104.41 ? 423 GLN B CD  1 
ATOM 4494 O OE1 . GLN B 1 349 ? 103.167 115.858 125.261 1.00 103.93 ? 423 GLN B OE1 1 
ATOM 4495 N NE2 . GLN B 1 349 ? 103.719 114.082 126.517 1.00 103.19 ? 423 GLN B NE2 1 
ATOM 4496 N N   . CYS B 1 350 ? 107.069 117.036 129.648 1.00 103.83 ? 424 CYS B N   1 
ATOM 4497 C CA  . CYS B 1 350 ? 107.791 117.395 130.866 1.00 105.23 ? 424 CYS B CA  1 
ATOM 4498 C C   . CYS B 1 350 ? 108.717 118.587 130.640 1.00 105.36 ? 424 CYS B C   1 
ATOM 4499 O O   . CYS B 1 350 ? 108.540 119.647 131.251 1.00 104.95 ? 424 CYS B O   1 
ATOM 4500 C CB  . CYS B 1 350 ? 108.576 116.189 131.387 1.00 103.13 ? 424 CYS B CB  1 
ATOM 4501 S SG  . CYS B 1 350 ? 109.192 116.385 133.075 1.00 103.21 ? 424 CYS B SG  1 
ATOM 4502 N N   . LEU B 1 351 ? 109.710 118.435 129.765 1.00 103.09 ? 425 LEU B N   1 
ATOM 4503 C CA  . LEU B 1 351 ? 110.664 119.499 129.476 1.00 101.07 ? 425 LEU B CA  1 
ATOM 4504 C C   . LEU B 1 351 ? 110.406 120.198 128.149 1.00 101.67 ? 425 LEU B C   1 
ATOM 4505 O O   . LEU B 1 351 ? 111.207 121.051 127.753 1.00 102.35 ? 425 LEU B O   1 
ATOM 4506 C CB  . LEU B 1 351 ? 112.098 118.956 129.497 1.00 101.43 ? 425 LEU B CB  1 
ATOM 4507 C CG  . LEU B 1 351 ? 112.777 118.779 130.860 1.00 102.83 ? 425 LEU B CG  1 
ATOM 4508 C CD1 . LEU B 1 351 ? 112.192 117.622 131.641 1.00 100.54 ? 425 LEU B CD1 1 
ATOM 4509 C CD2 . LEU B 1 351 ? 114.276 118.594 130.688 1.00 101.44 ? 425 LEU B CD2 1 
ATOM 4510 N N   . HIS B 1 352 ? 109.314 119.864 127.460 1.00 106.69 ? 426 HIS B N   1 
ATOM 4511 C CA  . HIS B 1 352 ? 108.941 120.495 126.192 1.00 105.49 ? 426 HIS B CA  1 
ATOM 4512 C C   . HIS B 1 352 ? 110.071 120.382 125.166 1.00 105.33 ? 426 HIS B C   1 
ATOM 4513 O O   . HIS B 1 352 ? 110.545 121.371 124.604 1.00 106.75 ? 426 HIS B O   1 
ATOM 4514 C CB  . HIS B 1 352 ? 108.531 121.956 126.408 1.00 106.39 ? 426 HIS B CB  1 
ATOM 4515 C CG  . HIS B 1 352 ? 107.514 122.144 127.491 1.00 106.98 ? 426 HIS B CG  1 
ATOM 4516 N ND1 . HIS B 1 352 ? 107.425 123.301 128.234 1.00 107.22 ? 426 HIS B ND1 1 
ATOM 4517 C CD2 . HIS B 1 352 ? 106.541 121.324 127.953 1.00 105.85 ? 426 HIS B CD2 1 
ATOM 4518 C CE1 . HIS B 1 352 ? 106.442 123.185 129.110 1.00 105.41 ? 426 HIS B CE1 1 
ATOM 4519 N NE2 . HIS B 1 352 ? 105.890 121.994 128.960 1.00 104.43 ? 426 HIS B NE2 1 
ATOM 4520 N N   . TRP B 1 353 ? 110.497 119.143 124.933 1.00 103.09 ? 427 TRP B N   1 
ATOM 4521 C CA  . TRP B 1 353 ? 111.543 118.872 123.956 1.00 104.63 ? 427 TRP B CA  1 
ATOM 4522 C C   . TRP B 1 353 ? 111.015 119.143 122.552 1.00 104.17 ? 427 TRP B C   1 
ATOM 4523 O O   . TRP B 1 353 ? 110.114 118.445 122.075 1.00 103.02 ? 427 TRP B O   1 
ATOM 4524 C CB  . TRP B 1 353 ? 112.018 117.428 124.092 1.00 105.69 ? 427 TRP B CB  1 
ATOM 4525 C CG  . TRP B 1 353 ? 112.895 116.952 122.974 1.00 105.69 ? 427 TRP B CG  1 
ATOM 4526 C CD1 . TRP B 1 353 ? 114.135 117.417 122.649 1.00 103.79 ? 427 TRP B CD1 1 
ATOM 4527 C CD2 . TRP B 1 353 ? 112.600 115.907 122.040 1.00 103.73 ? 427 TRP B CD2 1 
ATOM 4528 N NE1 . TRP B 1 353 ? 114.630 116.727 121.570 1.00 102.14 ? 427 TRP B NE1 1 
ATOM 4529 C CE2 . TRP B 1 353 ? 113.706 115.796 121.176 1.00 102.37 ? 427 TRP B CE2 1 
ATOM 4530 C CE3 . TRP B 1 353 ? 111.507 115.057 121.850 1.00 102.75 ? 427 TRP B CE3 1 
ATOM 4531 C CZ2 . TRP B 1 353 ? 113.751 114.869 120.138 1.00 102.84 ? 427 TRP B CZ2 1 
ATOM 4532 C CZ3 . TRP B 1 353 ? 111.553 114.139 120.818 1.00 103.51 ? 427 TRP B CZ3 1 
ATOM 4533 C CH2 . TRP B 1 353 ? 112.667 114.052 119.975 1.00 102.91 ? 427 TRP B CH2 1 
ATOM 4534 N N   . ASN B 1 354 ? 111.576 120.161 121.897 1.00 113.01 ? 428 ASN B N   1 
ATOM 4535 C CA  . ASN B 1 354 ? 111.156 120.606 120.568 1.00 112.47 ? 428 ASN B CA  1 
ATOM 4536 C C   . ASN B 1 354 ? 109.670 120.981 120.570 1.00 112.51 ? 428 ASN B C   1 
ATOM 4537 O O   . ASN B 1 354 ? 108.834 120.357 119.912 1.00 113.55 ? 428 ASN B O   1 
ATOM 4538 C CB  . ASN B 1 354 ? 111.460 119.543 119.505 1.00 113.47 ? 428 ASN B CB  1 
ATOM 4539 C CG  . ASN B 1 354 ? 111.256 120.055 118.089 1.00 116.13 ? 428 ASN B CG  1 
ATOM 4540 O OD1 . ASN B 1 354 ? 110.859 121.201 117.878 1.00 115.77 ? 428 ASN B OD1 1 
ATOM 4541 N ND2 . ASN B 1 354 ? 111.535 119.205 117.109 1.00 114.62 ? 428 ASN B ND2 1 
ATOM 4542 N N   . VAL B 1 355 ? 109.381 122.030 121.341 1.00 99.08  ? 429 VAL B N   1 
ATOM 4543 C CA  . VAL B 1 355 ? 108.046 122.620 121.512 1.00 100.82 ? 429 VAL B CA  1 
ATOM 4544 C C   . VAL B 1 355 ? 106.927 121.582 121.505 1.00 98.87  ? 429 VAL B C   1 
ATOM 4545 O O   . VAL B 1 355 ? 106.903 120.674 122.336 1.00 97.09  ? 429 VAL B O   1 
ATOM 4546 C CB  . VAL B 1 355 ? 107.770 123.709 120.439 1.00 102.72 ? 429 VAL B CB  1 
ATOM 4547 C CG1 . VAL B 1 355 ? 108.808 124.820 120.526 1.00 99.68  ? 429 VAL B CG1 1 
ATOM 4548 C CG2 . VAL B 1 355 ? 107.691 123.121 119.033 1.00 101.89 ? 429 VAL B CG2 1 
ATOM 4549 N N   . VAL C 1 22  ? 141.451 156.835 128.417 1.00 116.18 ? 96  VAL C N   1 
ATOM 4550 C CA  . VAL C 1 22  ? 141.029 157.721 127.341 1.00 119.05 ? 96  VAL C CA  1 
ATOM 4551 C C   . VAL C 1 22  ? 141.036 159.167 127.822 1.00 120.51 ? 96  VAL C C   1 
ATOM 4552 O O   . VAL C 1 22  ? 140.089 159.616 128.471 1.00 120.07 ? 96  VAL C O   1 
ATOM 4553 C CB  . VAL C 1 22  ? 139.640 157.330 126.808 1.00 120.86 ? 96  VAL C CB  1 
ATOM 4554 C CG1 . VAL C 1 22  ? 139.251 158.217 125.635 1.00 120.20 ? 96  VAL C CG1 1 
ATOM 4555 C CG2 . VAL C 1 22  ? 139.621 155.864 126.405 1.00 118.63 ? 96  VAL C CG2 1 
ATOM 4556 N N   . ARG C 1 23  ? 142.113 159.886 127.500 1.00 119.14 ? 97  ARG C N   1 
ATOM 4557 C CA  . ARG C 1 23  ? 142.287 161.287 127.884 1.00 117.87 ? 97  ARG C CA  1 
ATOM 4558 C C   . ARG C 1 23  ? 142.178 161.454 129.401 1.00 116.82 ? 97  ARG C C   1 
ATOM 4559 O O   . ARG C 1 23  ? 141.295 162.140 129.921 1.00 117.22 ? 97  ARG C O   1 
ATOM 4560 C CB  . ARG C 1 23  ? 141.254 162.170 127.180 1.00 116.66 ? 97  ARG C CB  1 
ATOM 4561 C CG  . ARG C 1 23  ? 141.439 162.260 125.674 1.00 116.29 ? 97  ARG C CG  1 
ATOM 4562 C CD  . ARG C 1 23  ? 140.442 163.174 124.980 1.00 117.09 ? 97  ARG C CD  1 
ATOM 4563 N NE  . ARG C 1 23  ? 140.616 163.174 123.530 1.00 118.33 ? 97  ARG C NE  1 
ATOM 4564 C CZ  . ARG C 1 23  ? 139.807 163.793 122.683 1.00 117.32 ? 97  ARG C CZ  1 
ATOM 4565 N NH1 . ARG C 1 23  ? 138.762 164.474 123.137 1.00 114.98 ? 97  ARG C NH1 1 
ATOM 4566 N NH2 . ARG C 1 23  ? 140.041 163.739 121.378 1.00 117.63 ? 97  ARG C NH2 1 
ATOM 4567 N N   . LEU C 1 24  ? 143.101 160.807 130.107 1.00 117.49 ? 98  LEU C N   1 
ATOM 4568 C CA  . LEU C 1 24  ? 143.106 160.843 131.563 1.00 119.31 ? 98  LEU C CA  1 
ATOM 4569 C C   . LEU C 1 24  ? 143.772 162.121 132.055 1.00 119.42 ? 98  LEU C C   1 
ATOM 4570 O O   . LEU C 1 24  ? 144.917 162.414 131.698 1.00 119.13 ? 98  LEU C O   1 
ATOM 4571 C CB  . LEU C 1 24  ? 143.830 159.618 132.123 1.00 118.10 ? 98  LEU C CB  1 
ATOM 4572 C CG  . LEU C 1 24  ? 144.204 159.668 133.605 1.00 117.48 ? 98  LEU C CG  1 
ATOM 4573 C CD1 . LEU C 1 24  ? 142.958 159.662 134.477 1.00 116.53 ? 98  LEU C CD1 1 
ATOM 4574 C CD2 . LEU C 1 24  ? 145.122 158.511 133.966 1.00 116.14 ? 98  LEU C CD2 1 
ATOM 4575 N N   . THR C 1 25  ? 143.050 162.881 132.876 1.00 119.36 ? 99  THR C N   1 
ATOM 4576 C CA  . THR C 1 25  ? 143.557 164.115 133.458 1.00 118.80 ? 99  THR C CA  1 
ATOM 4577 C C   . THR C 1 25  ? 143.534 163.990 134.973 1.00 117.25 ? 99  THR C C   1 
ATOM 4578 O O   . THR C 1 25  ? 142.494 163.666 135.556 1.00 116.20 ? 99  THR C O   1 
ATOM 4579 C CB  . THR C 1 25  ? 142.729 165.326 133.015 1.00 118.77 ? 99  THR C CB  1 
ATOM 4580 O OG1 . THR C 1 25  ? 142.632 165.344 131.585 1.00 117.68 ? 99  THR C OG1 1 
ATOM 4581 C CG2 . THR C 1 25  ? 143.376 166.618 133.491 1.00 117.07 ? 99  THR C CG2 1 
ATOM 4582 N N   . TRP C 1 26  ? 144.677 164.246 135.606 1.00 108.17 ? 100 TRP C N   1 
ATOM 4583 C CA  . TRP C 1 26  ? 144.795 164.136 137.052 1.00 106.93 ? 100 TRP C CA  1 
ATOM 4584 C C   . TRP C 1 26  ? 144.350 165.390 137.790 1.00 106.35 ? 100 TRP C C   1 
ATOM 4585 O O   . TRP C 1 26  ? 144.228 165.348 139.019 1.00 105.53 ? 100 TRP C O   1 
ATOM 4586 C CB  . TRP C 1 26  ? 146.242 163.816 137.446 1.00 103.75 ? 100 TRP C CB  1 
ATOM 4587 C CG  . TRP C 1 26  ? 146.700 162.457 137.028 1.00 104.21 ? 100 TRP C CG  1 
ATOM 4588 C CD1 . TRP C 1 26  ? 147.489 162.153 135.960 1.00 103.81 ? 100 TRP C CD1 1 
ATOM 4589 C CD2 . TRP C 1 26  ? 146.394 161.214 137.668 1.00 105.54 ? 100 TRP C CD2 1 
ATOM 4590 N NE1 . TRP C 1 26  ? 147.698 160.797 135.896 1.00 102.32 ? 100 TRP C NE1 1 
ATOM 4591 C CE2 . TRP C 1 26  ? 147.035 160.198 136.934 1.00 105.02 ? 100 TRP C CE2 1 
ATOM 4592 C CE3 . TRP C 1 26  ? 145.641 160.861 138.791 1.00 106.02 ? 100 TRP C CE3 1 
ATOM 4593 C CZ2 . TRP C 1 26  ? 146.945 158.853 137.285 1.00 106.44 ? 100 TRP C CZ2 1 
ATOM 4594 C CZ3 . TRP C 1 26  ? 145.554 159.526 139.139 1.00 104.71 ? 100 TRP C CZ3 1 
ATOM 4595 C CH2 . TRP C 1 26  ? 146.202 158.539 138.389 1.00 104.10 ? 100 TRP C CH2 1 
ATOM 4596 N N   . ASN C 1 27  ? 144.125 166.498 137.078 1.00 111.51 ? 101 ASN C N   1 
ATOM 4597 C CA  . ASN C 1 27  ? 143.779 167.782 137.681 1.00 111.78 ? 101 ASN C CA  1 
ATOM 4598 C C   . ASN C 1 27  ? 144.921 168.261 138.568 1.00 111.55 ? 101 ASN C C   1 
ATOM 4599 O O   . ASN C 1 27  ? 145.611 169.232 138.238 1.00 112.19 ? 101 ASN C O   1 
ATOM 4600 C CB  . ASN C 1 27  ? 142.471 167.691 138.475 1.00 111.30 ? 101 ASN C CB  1 
ATOM 4601 C CG  . ASN C 1 27  ? 141.344 167.070 137.674 1.00 111.06 ? 101 ASN C CG  1 
ATOM 4602 O OD1 . ASN C 1 27  ? 140.963 167.578 136.620 1.00 111.21 ? 101 ASN C OD1 1 
ATOM 4603 N ND2 . ASN C 1 27  ? 140.806 165.962 138.171 1.00 110.57 ? 101 ASN C ND2 1 
ATOM 4604 N N   . LYS C 1 28  ? 145.126 167.585 139.694 1.00 106.21 ? 102 LYS C N   1 
ATOM 4605 C CA  . LYS C 1 28  ? 146.272 167.808 140.563 1.00 106.05 ? 102 LYS C CA  1 
ATOM 4606 C C   . LYS C 1 28  ? 147.157 166.571 140.514 1.00 105.99 ? 102 LYS C C   1 
ATOM 4607 O O   . LYS C 1 28  ? 146.649 165.445 140.466 1.00 105.28 ? 102 LYS C O   1 
ATOM 4608 C CB  . LYS C 1 28  ? 145.825 168.097 141.999 1.00 105.62 ? 102 LYS C CB  1 
ATOM 4609 C CG  . LYS C 1 28  ? 146.954 168.132 143.017 1.00 105.38 ? 102 LYS C CG  1 
ATOM 4610 C CD  . LYS C 1 28  ? 146.519 167.543 144.349 1.00 106.04 ? 102 LYS C CD  1 
ATOM 4611 C CE  . LYS C 1 28  ? 146.076 166.097 144.194 1.00 104.85 ? 102 LYS C CE  1 
ATOM 4612 N NZ  . LYS C 1 28  ? 145.701 165.487 145.499 1.00 104.84 ? 102 LYS C NZ  1 
ATOM 4613 N N   . SER C 1 29  ? 148.475 166.781 140.514 1.00 100.14 ? 103 SER C N   1 
ATOM 4614 C CA  . SER C 1 29  ? 149.437 165.691 140.412 1.00 97.93  ? 103 SER C CA  1 
ATOM 4615 C C   . SER C 1 29  ? 149.207 164.687 141.534 1.00 96.20  ? 103 SER C C   1 
ATOM 4616 O O   . SER C 1 29  ? 148.939 165.084 142.676 1.00 95.25  ? 103 SER C O   1 
ATOM 4617 C CB  . SER C 1 29  ? 150.869 166.227 140.461 1.00 95.61  ? 103 SER C CB  1 
ATOM 4618 O OG  . SER C 1 29  ? 151.115 167.123 139.391 1.00 95.82  ? 103 SER C OG  1 
ATOM 4619 N N   . PRO C 1 30  ? 149.285 163.387 141.250 1.00 90.54  ? 104 PRO C N   1 
ATOM 4620 C CA  . PRO C 1 30  ? 148.973 162.391 142.279 1.00 90.61  ? 104 PRO C CA  1 
ATOM 4621 C C   . PRO C 1 30  ? 149.938 162.466 143.452 1.00 95.70  ? 104 PRO C C   1 
ATOM 4622 O O   . PRO C 1 30  ? 151.139 162.690 143.288 1.00 96.14  ? 104 PRO C O   1 
ATOM 4623 C CB  . PRO C 1 30  ? 149.099 161.060 141.532 1.00 87.05  ? 104 PRO C CB  1 
ATOM 4624 C CG  . PRO C 1 30  ? 150.069 161.341 140.447 1.00 85.36  ? 104 PRO C CG  1 
ATOM 4625 C CD  . PRO C 1 30  ? 149.837 162.769 140.032 1.00 88.58  ? 104 PRO C CD  1 
ATOM 4626 N N   . LYS C 1 31  ? 149.390 162.281 144.652 1.00 98.52  ? 105 LYS C N   1 
ATOM 4627 C CA  . LYS C 1 31  ? 150.178 162.289 145.877 1.00 95.28  ? 105 LYS C CA  1 
ATOM 4628 C C   . LYS C 1 31  ? 149.865 161.141 146.822 1.00 94.29  ? 105 LYS C C   1 
ATOM 4629 O O   . LYS C 1 31  ? 150.696 160.844 147.688 1.00 92.07  ? 105 LYS C O   1 
ATOM 4630 C CB  . LYS C 1 31  ? 149.978 163.616 146.610 1.00 94.17  ? 105 LYS C CB  1 
ATOM 4631 C CG  . LYS C 1 31  ? 150.519 164.826 145.865 1.00 94.39  ? 105 LYS C CG  1 
ATOM 4632 C CD  . LYS C 1 31  ? 150.266 166.110 146.636 1.00 95.08  ? 105 LYS C CD  1 
ATOM 4633 C CE  . LYS C 1 31  ? 150.827 167.317 145.902 1.00 94.60  ? 105 LYS C CE  1 
ATOM 4634 N NZ  . LYS C 1 31  ? 150.565 168.585 146.635 1.00 95.06  ? 105 LYS C NZ  1 
ATOM 4635 N N   . SER C 1 32  ? 148.711 160.492 146.695 1.00 84.84  ? 106 SER C N   1 
ATOM 4636 C CA  . SER C 1 32  ? 148.322 159.389 147.562 1.00 80.99  ? 106 SER C CA  1 
ATOM 4637 C C   . SER C 1 32  ? 148.169 158.126 146.730 1.00 77.34  ? 106 SER C C   1 
ATOM 4638 O O   . SER C 1 32  ? 147.463 158.127 145.717 1.00 82.07  ? 106 SER C O   1 
ATOM 4639 C CB  . SER C 1 32  ? 147.017 159.702 148.300 1.00 85.25  ? 106 SER C CB  1 
ATOM 4640 O OG  . SER C 1 32  ? 146.574 158.584 149.049 1.00 86.30  ? 106 SER C OG  1 
ATOM 4641 N N   . VAL C 1 33  ? 148.832 157.056 147.158 1.00 62.39  ? 107 VAL C N   1 
ATOM 4642 C CA  . VAL C 1 33  ? 148.766 155.761 146.494 1.00 68.65  ? 107 VAL C CA  1 
ATOM 4643 C C   . VAL C 1 33  ? 148.315 154.725 147.512 1.00 69.94  ? 107 VAL C C   1 
ATOM 4644 O O   . VAL C 1 33  ? 148.928 154.587 148.576 1.00 74.44  ? 107 VAL C O   1 
ATOM 4645 C CB  . VAL C 1 33  ? 150.121 155.362 145.881 1.00 69.00  ? 107 VAL C CB  1 
ATOM 4646 C CG1 . VAL C 1 33  ? 150.080 153.925 145.395 1.00 70.99  ? 107 VAL C CG1 1 
ATOM 4647 C CG2 . VAL C 1 33  ? 150.480 156.298 144.742 1.00 70.81  ? 107 VAL C CG2 1 
ATOM 4648 N N   . LEU C 1 34  ? 147.248 154.000 147.187 1.00 56.24  ? 108 LEU C N   1 
ATOM 4649 C CA  . LEU C 1 34  ? 146.741 152.923 148.027 1.00 45.03  ? 108 LEU C CA  1 
ATOM 4650 C C   . LEU C 1 34  ? 147.080 151.596 147.364 1.00 50.60  ? 108 LEU C C   1 
ATOM 4651 O O   . LEU C 1 34  ? 146.582 151.300 146.273 1.00 59.28  ? 108 LEU C O   1 
ATOM 4652 C CB  . LEU C 1 34  ? 145.236 153.053 148.240 1.00 43.12  ? 108 LEU C CB  1 
ATOM 4653 C CG  . LEU C 1 34  ? 144.600 151.945 149.079 1.00 58.56  ? 108 LEU C CG  1 
ATOM 4654 C CD1 . LEU C 1 34  ? 145.184 151.932 150.483 1.00 59.76  ? 108 LEU C CD1 1 
ATOM 4655 C CD2 . LEU C 1 34  ? 143.091 152.105 149.125 1.00 60.63  ? 108 LEU C CD2 1 
ATOM 4656 N N   . VAL C 1 35  ? 147.919 150.802 148.023 1.00 51.09  ? 109 VAL C N   1 
ATOM 4657 C CA  . VAL C 1 35  ? 148.404 149.537 147.485 1.00 46.49  ? 109 VAL C CA  1 
ATOM 4658 C C   . VAL C 1 35  ? 147.724 148.400 148.230 1.00 52.42  ? 109 VAL C C   1 
ATOM 4659 O O   . VAL C 1 35  ? 147.774 148.340 149.464 1.00 66.55  ? 109 VAL C O   1 
ATOM 4660 C CB  . VAL C 1 35  ? 149.932 149.425 147.594 1.00 55.99  ? 109 VAL C CB  1 
ATOM 4661 C CG1 . VAL C 1 35  ? 150.407 148.117 146.991 1.00 60.09  ? 109 VAL C CG1 1 
ATOM 4662 C CG2 . VAL C 1 35  ? 150.595 150.604 146.909 1.00 58.14  ? 109 VAL C CG2 1 
ATOM 4663 N N   . ILE C 1 36  ? 147.094 147.501 147.481 1.00 51.11  ? 110 ILE C N   1 
ATOM 4664 C CA  . ILE C 1 36  ? 146.400 146.347 148.035 1.00 51.59  ? 110 ILE C CA  1 
ATOM 4665 C C   . ILE C 1 36  ? 147.065 145.090 147.496 1.00 55.71  ? 110 ILE C C   1 
ATOM 4666 O O   . ILE C 1 36  ? 147.234 144.944 146.280 1.00 62.29  ? 110 ILE C O   1 
ATOM 4667 C CB  . ILE C 1 36  ? 144.899 146.355 147.689 1.00 49.34  ? 110 ILE C CB  1 
ATOM 4668 C CG1 . ILE C 1 36  ? 144.200 147.575 148.290 1.00 49.48  ? 110 ILE C CG1 1 
ATOM 4669 C CG2 . ILE C 1 36  ? 144.238 145.077 148.169 1.00 57.01  ? 110 ILE C CG2 1 
ATOM 4670 C CD1 . ILE C 1 36  ? 144.160 148.776 147.383 1.00 51.09  ? 110 ILE C CD1 1 
ATOM 4671 N N   . LYS C 1 37  ? 147.438 144.190 148.396 1.00 75.84  ? 111 LYS C N   1 
ATOM 4672 C CA  . LYS C 1 37  ? 148.037 142.915 148.042 1.00 79.16  ? 111 LYS C CA  1 
ATOM 4673 C C   . LYS C 1 37  ? 147.002 141.807 148.194 1.00 86.99  ? 111 LYS C C   1 
ATOM 4674 O O   . LYS C 1 37  ? 146.075 141.910 149.002 1.00 89.69  ? 111 LYS C O   1 
ATOM 4675 C CB  . LYS C 1 37  ? 149.255 142.622 148.923 1.00 86.78  ? 111 LYS C CB  1 
ATOM 4676 C CG  . LYS C 1 37  ? 150.088 141.426 148.488 1.00 88.47  ? 111 LYS C CG  1 
ATOM 4677 C CD  . LYS C 1 37  ? 151.279 141.225 149.409 1.00 88.58  ? 111 LYS C CD  1 
ATOM 4678 C CE  . LYS C 1 37  ? 150.826 140.992 150.839 1.00 84.78  ? 111 LYS C CE  1 
ATOM 4679 N NZ  . LYS C 1 37  ? 151.971 140.792 151.765 1.00 86.66  ? 111 LYS C NZ  1 
ATOM 4680 N N   . LYS C 1 38  ? 147.167 140.744 147.404 1.00 100.33 ? 112 LYS C N   1 
ATOM 4681 C CA  . LYS C 1 38  ? 146.256 139.608 147.483 1.00 103.94 ? 112 LYS C CA  1 
ATOM 4682 C C   . LYS C 1 38  ? 146.304 138.926 148.845 1.00 102.82 ? 112 LYS C C   1 
ATOM 4683 O O   . LYS C 1 38  ? 145.330 138.269 149.230 1.00 101.97 ? 112 LYS C O   1 
ATOM 4684 C CB  . LYS C 1 38  ? 146.583 138.605 146.372 1.00 102.49 ? 112 LYS C CB  1 
ATOM 4685 C CG  . LYS C 1 38  ? 145.661 137.396 146.304 1.00 101.75 ? 112 LYS C CG  1 
ATOM 4686 C CD  . LYS C 1 38  ? 145.973 136.533 145.094 1.00 100.88 ? 112 LYS C CD  1 
ATOM 4687 C CE  . LYS C 1 38  ? 147.269 135.763 145.285 1.00 99.93  ? 112 LYS C CE  1 
ATOM 4688 N NZ  . LYS C 1 38  ? 147.530 134.825 144.159 1.00 98.79  ? 112 LYS C NZ  1 
ATOM 4689 N N   . MET C 1 39  ? 147.411 139.074 149.578 1.00 111.35 ? 113 MET C N   1 
ATOM 4690 C CA  . MET C 1 39  ? 147.601 138.503 150.910 1.00 112.57 ? 113 MET C CA  1 
ATOM 4691 C C   . MET C 1 39  ? 147.640 136.979 150.876 1.00 113.32 ? 113 MET C C   1 
ATOM 4692 O O   . MET C 1 39  ? 147.242 136.359 149.884 1.00 112.69 ? 113 MET C O   1 
ATOM 4693 C CB  . MET C 1 39  ? 146.508 138.980 151.872 1.00 111.05 ? 113 MET C CB  1 
ATOM 4694 C CG  . MET C 1 39  ? 146.432 140.488 152.031 1.00 110.72 ? 113 MET C CG  1 
ATOM 4695 S SD  . MET C 1 39  ? 147.874 141.157 152.877 1.00 118.93 ? 113 MET C SD  1 
ATOM 4696 C CE  . MET C 1 39  ? 147.696 140.401 154.491 1.00 111.25 ? 113 MET C CE  1 
ATOM 4697 N N   . ARG C 1 40  ? 148.127 136.373 151.961 1.00 113.48 ? 114 ARG C N   1 
ATOM 4698 C CA  . ARG C 1 40  ? 148.215 134.918 152.089 1.00 113.79 ? 114 ARG C CA  1 
ATOM 4699 C C   . ARG C 1 40  ? 148.988 134.299 150.927 1.00 112.66 ? 114 ARG C C   1 
ATOM 4700 O O   . ARG C 1 40  ? 148.636 133.232 150.421 1.00 112.91 ? 114 ARG C O   1 
ATOM 4701 C CB  . ARG C 1 40  ? 146.825 134.289 152.209 1.00 114.03 ? 114 ARG C CB  1 
ATOM 4702 C CG  . ARG C 1 40  ? 146.050 134.711 153.446 1.00 113.23 ? 114 ARG C CG  1 
ATOM 4703 C CD  . ARG C 1 40  ? 144.632 134.165 153.416 1.00 112.71 ? 114 ARG C CD  1 
ATOM 4704 N NE  . ARG C 1 40  ? 144.609 132.718 153.236 1.00 114.53 ? 114 ARG C NE  1 
ATOM 4705 C CZ  . ARG C 1 40  ? 143.504 131.995 153.114 1.00 115.74 ? 114 ARG C CZ  1 
ATOM 4706 N NH1 . ARG C 1 40  ? 142.305 132.554 153.148 1.00 115.57 ? 114 ARG C NH1 1 
ATOM 4707 N NH2 . ARG C 1 40  ? 143.604 130.679 152.955 1.00 114.03 ? 114 ARG C NH2 1 
ATOM 4708 N N   . ASP C 1 41  ? 150.053 134.972 150.498 1.00 102.50 ? 115 ASP C N   1 
ATOM 4709 C CA  . ASP C 1 41  ? 150.856 134.493 149.378 1.00 102.19 ? 115 ASP C CA  1 
ATOM 4710 C C   . ASP C 1 41  ? 152.297 134.927 149.589 1.00 105.12 ? 115 ASP C C   1 
ATOM 4711 O O   . ASP C 1 41  ? 152.593 136.125 149.575 1.00 105.95 ? 115 ASP C O   1 
ATOM 4712 C CB  . ASP C 1 41  ? 150.320 135.027 148.048 1.00 102.97 ? 115 ASP C CB  1 
ATOM 4713 C CG  . ASP C 1 41  ? 150.914 134.312 146.849 1.00 104.76 ? 115 ASP C CG  1 
ATOM 4714 O OD1 . ASP C 1 41  ? 151.732 133.390 147.046 1.00 103.46 ? 115 ASP C OD1 1 
ATOM 4715 O OD2 . ASP C 1 41  ? 150.561 134.674 145.707 1.00 103.93 ? 115 ASP C OD2 1 
ATOM 4716 N N   . ALA C 1 42  ? 153.187 133.952 149.784 1.00 104.02 ? 116 ALA C N   1 
ATOM 4717 C CA  . ALA C 1 42  ? 154.603 134.264 149.943 1.00 104.00 ? 116 ALA C CA  1 
ATOM 4718 C C   . ALA C 1 42  ? 155.211 134.795 148.652 1.00 102.38 ? 116 ALA C C   1 
ATOM 4719 O O   . ALA C 1 42  ? 156.121 135.630 148.695 1.00 100.93 ? 116 ALA C O   1 
ATOM 4720 C CB  . ALA C 1 42  ? 155.364 133.028 150.420 1.00 102.64 ? 116 ALA C CB  1 
ATOM 4721 N N   . SER C 1 43  ? 154.724 134.326 147.500 1.00 98.68  ? 117 SER C N   1 
ATOM 4722 C CA  . SER C 1 43  ? 155.281 134.750 146.221 1.00 99.85  ? 117 SER C CA  1 
ATOM 4723 C C   . SER C 1 43  ? 155.108 136.241 145.976 1.00 100.48 ? 117 SER C C   1 
ATOM 4724 O O   . SER C 1 43  ? 155.893 136.828 145.224 1.00 101.76 ? 117 SER C O   1 
ATOM 4725 C CB  . SER C 1 43  ? 154.636 133.959 145.082 1.00 100.56 ? 117 SER C CB  1 
ATOM 4726 O OG  . SER C 1 43  ? 155.164 134.351 143.827 1.00 98.95  ? 117 SER C OG  1 
ATOM 4727 N N   . LEU C 1 44  ? 154.104 136.866 146.585 1.00 98.51  ? 118 LEU C N   1 
ATOM 4728 C CA  . LEU C 1 44  ? 153.865 138.292 146.417 1.00 98.45  ? 118 LEU C CA  1 
ATOM 4729 C C   . LEU C 1 44  ? 154.542 139.137 147.486 1.00 100.22 ? 118 LEU C C   1 
ATOM 4730 O O   . LEU C 1 44  ? 154.392 140.363 147.471 1.00 103.31 ? 118 LEU C O   1 
ATOM 4731 C CB  . LEU C 1 44  ? 152.362 138.579 146.414 1.00 98.76  ? 118 LEU C CB  1 
ATOM 4732 C CG  . LEU C 1 44  ? 151.557 137.881 145.318 1.00 101.94 ? 118 LEU C CG  1 
ATOM 4733 C CD1 . LEU C 1 44  ? 150.088 138.254 145.410 1.00 99.96  ? 118 LEU C CD1 1 
ATOM 4734 C CD2 . LEU C 1 44  ? 152.115 138.220 143.946 1.00 99.06  ? 118 LEU C CD2 1 
ATOM 4735 N N   . LEU C 1 45  ? 155.277 138.519 148.412 1.00 103.03 ? 119 LEU C N   1 
ATOM 4736 C CA  . LEU C 1 45  ? 155.949 139.284 149.457 1.00 104.18 ? 119 LEU C CA  1 
ATOM 4737 C C   . LEU C 1 45  ? 157.092 140.111 148.882 1.00 104.40 ? 119 LEU C C   1 
ATOM 4738 O O   . LEU C 1 45  ? 157.138 141.334 149.052 1.00 103.19 ? 119 LEU C O   1 
ATOM 4739 C CB  . LEU C 1 45  ? 156.458 138.344 150.552 1.00 104.50 ? 119 LEU C CB  1 
ATOM 4740 C CG  . LEU C 1 45  ? 155.402 137.591 151.363 1.00 105.73 ? 119 LEU C CG  1 
ATOM 4741 C CD1 . LEU C 1 45  ? 156.066 136.656 152.361 1.00 103.21 ? 119 LEU C CD1 1 
ATOM 4742 C CD2 . LEU C 1 45  ? 154.475 138.564 152.071 1.00 105.30 ? 119 LEU C CD2 1 
ATOM 4743 N N   . GLN C 1 46  ? 158.028 139.455 148.196 1.00 106.05 ? 120 GLN C N   1 
ATOM 4744 C CA  . GLN C 1 46  ? 159.184 140.166 147.650 1.00 105.75 ? 120 GLN C CA  1 
ATOM 4745 C C   . GLN C 1 46  ? 158.804 141.229 146.626 1.00 104.54 ? 120 GLN C C   1 
ATOM 4746 O O   . GLN C 1 46  ? 159.314 142.358 146.730 1.00 102.03 ? 120 GLN C O   1 
ATOM 4747 C CB  . GLN C 1 46  ? 160.181 139.157 147.070 1.00 103.77 ? 120 GLN C CB  1 
ATOM 4748 C CG  . GLN C 1 46  ? 161.436 139.788 146.497 1.00 104.19 ? 120 GLN C CG  1 
ATOM 4749 C CD  . GLN C 1 46  ? 162.355 138.771 145.853 1.00 105.49 ? 120 GLN C CD  1 
ATOM 4750 O OE1 . GLN C 1 46  ? 161.987 137.610 145.676 1.00 104.08 ? 120 GLN C OE1 1 
ATOM 4751 N NE2 . GLN C 1 46  ? 163.559 139.203 145.497 1.00 106.03 ? 120 GLN C NE2 1 
ATOM 4752 N N   . PRO C 1 47  ? 157.951 140.961 145.627 1.00 104.45 ? 121 PRO C N   1 
ATOM 4753 C CA  . PRO C 1 47  ? 157.576 142.041 144.698 1.00 103.40 ? 121 PRO C CA  1 
ATOM 4754 C C   . PRO C 1 47  ? 156.893 143.211 145.378 1.00 100.65 ? 121 PRO C C   1 
ATOM 4755 O O   . PRO C 1 47  ? 157.011 144.348 144.904 1.00 101.61 ? 121 PRO C O   1 
ATOM 4756 C CB  . PRO C 1 47  ? 156.641 141.340 143.704 1.00 103.25 ? 121 PRO C CB  1 
ATOM 4757 C CG  . PRO C 1 47  ? 157.000 139.903 143.792 1.00 102.33 ? 121 PRO C CG  1 
ATOM 4758 C CD  . PRO C 1 47  ? 157.347 139.678 145.226 1.00 103.61 ? 121 PRO C CD  1 
ATOM 4759 N N   . PHE C 1 48  ? 156.174 142.966 146.475 1.00 92.38  ? 122 PHE C N   1 
ATOM 4760 C CA  . PHE C 1 48  ? 155.564 144.062 147.219 1.00 95.28  ? 122 PHE C CA  1 
ATOM 4761 C C   . PHE C 1 48  ? 156.625 144.999 147.781 1.00 96.71  ? 122 PHE C C   1 
ATOM 4762 O O   . PHE C 1 48  ? 156.436 146.221 147.805 1.00 97.05  ? 122 PHE C O   1 
ATOM 4763 C CB  . PHE C 1 48  ? 154.683 143.506 148.338 1.00 95.47  ? 122 PHE C CB  1 
ATOM 4764 C CG  . PHE C 1 48  ? 154.101 144.559 149.237 1.00 90.39  ? 122 PHE C CG  1 
ATOM 4765 C CD1 . PHE C 1 48  ? 153.004 145.299 148.839 1.00 90.57  ? 122 PHE C CD1 1 
ATOM 4766 C CD2 . PHE C 1 48  ? 154.643 144.796 150.488 1.00 93.46  ? 122 PHE C CD2 1 
ATOM 4767 C CE1 . PHE C 1 48  ? 152.465 146.262 149.664 1.00 88.99  ? 122 PHE C CE1 1 
ATOM 4768 C CE2 . PHE C 1 48  ? 154.108 145.759 151.318 1.00 95.96  ? 122 PHE C CE2 1 
ATOM 4769 C CZ  . PHE C 1 48  ? 153.016 146.492 150.905 1.00 92.54  ? 122 PHE C CZ  1 
ATOM 4770 N N   . LYS C 1 49  ? 157.745 144.442 148.247 1.00 102.23 ? 123 LYS C N   1 
ATOM 4771 C CA  . LYS C 1 49  ? 158.806 145.271 148.811 1.00 103.18 ? 123 LYS C CA  1 
ATOM 4772 C C   . LYS C 1 49  ? 159.423 146.184 147.758 1.00 102.10 ? 123 LYS C C   1 
ATOM 4773 O O   . LYS C 1 49  ? 159.685 147.363 148.026 1.00 100.69 ? 123 LYS C O   1 
ATOM 4774 C CB  . LYS C 1 49  ? 159.880 144.387 149.447 1.00 104.01 ? 123 LYS C CB  1 
ATOM 4775 C CG  . LYS C 1 49  ? 159.338 143.257 150.313 1.00 103.28 ? 123 LYS C CG  1 
ATOM 4776 C CD  . LYS C 1 49  ? 158.450 143.788 151.429 1.00 103.19 ? 123 LYS C CD  1 
ATOM 4777 C CE  . LYS C 1 49  ? 157.945 142.672 152.329 1.00 102.70 ? 123 LYS C CE  1 
ATOM 4778 N NZ  . LYS C 1 49  ? 157.130 141.675 151.586 1.00 102.87 ? 123 LYS C NZ  1 
ATOM 4779 N N   . GLU C 1 50  ? 159.668 145.658 146.555 1.00 100.66 ? 124 GLU C N   1 
ATOM 4780 C CA  . GLU C 1 50  ? 160.339 146.445 145.524 1.00 99.35  ? 124 GLU C CA  1 
ATOM 4781 C C   . GLU C 1 50  ? 159.498 147.640 145.095 1.00 98.87  ? 124 GLU C C   1 
ATOM 4782 O O   . GLU C 1 50  ? 160.023 148.746 144.924 1.00 97.10  ? 124 GLU C O   1 
ATOM 4783 C CB  . GLU C 1 50  ? 160.665 145.562 144.321 1.00 99.16  ? 124 GLU C CB  1 
ATOM 4784 C CG  . GLU C 1 50  ? 161.542 144.366 144.649 1.00 100.88 ? 124 GLU C CG  1 
ATOM 4785 C CD  . GLU C 1 50  ? 161.800 143.485 143.443 1.00 102.93 ? 124 GLU C CD  1 
ATOM 4786 O OE1 . GLU C 1 50  ? 161.303 143.816 142.346 1.00 101.96 ? 124 GLU C OE1 1 
ATOM 4787 O OE2 . GLU C 1 50  ? 162.499 142.460 143.592 1.00 102.64 ? 124 GLU C OE2 1 
ATOM 4788 N N   . LEU C 1 51  ? 158.191 147.436 144.909 1.00 99.96  ? 125 LEU C N   1 
ATOM 4789 C CA  . LEU C 1 51  ? 157.328 148.523 144.458 1.00 101.71 ? 125 LEU C CA  1 
ATOM 4790 C C   . LEU C 1 51  ? 157.218 149.623 145.506 1.00 99.68  ? 125 LEU C C   1 
ATOM 4791 O O   . LEU C 1 51  ? 157.282 150.812 145.174 1.00 100.52 ? 125 LEU C O   1 
ATOM 4792 C CB  . LEU C 1 51  ? 155.943 147.982 144.104 1.00 103.43 ? 125 LEU C CB  1 
ATOM 4793 C CG  . LEU C 1 51  ? 154.913 149.013 143.634 1.00 99.57  ? 125 LEU C CG  1 
ATOM 4794 C CD1 . LEU C 1 51  ? 155.400 149.731 142.386 1.00 97.68  ? 125 LEU C CD1 1 
ATOM 4795 C CD2 . LEU C 1 51  ? 153.568 148.353 143.386 1.00 95.91  ? 125 LEU C CD2 1 
ATOM 4796 N N   . CYS C 1 52  ? 157.051 149.246 146.776 1.00 93.69  ? 126 CYS C N   1 
ATOM 4797 C CA  . CYS C 1 52  ? 156.857 150.246 147.821 1.00 93.10  ? 126 CYS C CA  1 
ATOM 4798 C C   . CYS C 1 52  ? 158.092 151.120 147.987 1.00 99.62  ? 126 CYS C C   1 
ATOM 4799 O O   . CYS C 1 52  ? 157.978 152.319 148.266 1.00 101.40 ? 126 CYS C O   1 
ATOM 4800 C CB  . CYS C 1 52  ? 156.494 149.564 149.137 1.00 92.52  ? 126 CYS C CB  1 
ATOM 4801 S SG  . CYS C 1 52  ? 154.926 148.682 149.090 1.00 85.22  ? 126 CYS C SG  1 
ATOM 4802 N N   . THR C 1 53  ? 159.282 150.538 147.826 1.00 102.07 ? 127 THR C N   1 
ATOM 4803 C CA  . THR C 1 53  ? 160.503 151.334 147.889 1.00 97.79  ? 127 THR C CA  1 
ATOM 4804 C C   . THR C 1 53  ? 160.540 152.368 146.772 1.00 96.60  ? 127 THR C C   1 
ATOM 4805 O O   . THR C 1 53  ? 160.914 153.524 146.999 1.00 95.87  ? 127 THR C O   1 
ATOM 4806 C CB  . THR C 1 53  ? 161.730 150.427 147.815 1.00 96.44  ? 127 THR C CB  1 
ATOM 4807 O OG1 . THR C 1 53  ? 161.605 149.542 146.696 1.00 98.51  ? 127 THR C OG1 1 
ATOM 4808 C CG2 . THR C 1 53  ? 161.865 149.609 149.090 1.00 95.32  ? 127 THR C CG2 1 
ATOM 4809 N N   . HIS C 1 54  ? 160.152 151.972 145.558 1.00 103.83 ? 128 HIS C N   1 
ATOM 4810 C CA  . HIS C 1 54  ? 160.146 152.917 144.446 1.00 106.91 ? 128 HIS C CA  1 
ATOM 4811 C C   . HIS C 1 54  ? 159.061 153.972 144.621 1.00 108.01 ? 128 HIS C C   1 
ATOM 4812 O O   . HIS C 1 54  ? 159.293 155.156 144.352 1.00 108.51 ? 128 HIS C O   1 
ATOM 4813 C CB  . HIS C 1 54  ? 159.962 152.175 143.123 1.00 108.61 ? 128 HIS C CB  1 
ATOM 4814 C CG  . HIS C 1 54  ? 159.908 153.079 141.931 1.00 108.78 ? 128 HIS C CG  1 
ATOM 4815 N ND1 . HIS C 1 54  ? 158.725 153.440 141.323 1.00 106.62 ? 128 HIS C ND1 1 
ATOM 4816 C CD2 . HIS C 1 54  ? 160.891 153.697 141.236 1.00 107.61 ? 128 HIS C CD2 1 
ATOM 4817 C CE1 . HIS C 1 54  ? 158.982 154.241 140.305 1.00 105.48 ? 128 HIS C CE1 1 
ATOM 4818 N NE2 . HIS C 1 54  ? 160.289 154.413 140.230 1.00 105.35 ? 128 HIS C NE2 1 
ATOM 4819 N N   . LEU C 1 55  ? 157.867 153.562 145.057 1.00 103.11 ? 129 LEU C N   1 
ATOM 4820 C CA  . LEU C 1 55  ? 156.792 154.525 145.273 1.00 100.65 ? 129 LEU C CA  1 
ATOM 4821 C C   . LEU C 1 55  ? 157.154 155.514 146.371 1.00 97.77  ? 129 LEU C C   1 
ATOM 4822 O O   . LEU C 1 55  ? 156.882 156.714 146.252 1.00 99.44  ? 129 LEU C O   1 
ATOM 4823 C CB  . LEU C 1 55  ? 155.490 153.799 145.612 1.00 100.26 ? 129 LEU C CB  1 
ATOM 4824 C CG  . LEU C 1 55  ? 154.886 152.926 144.510 1.00 103.29 ? 129 LEU C CG  1 
ATOM 4825 C CD1 . LEU C 1 55  ? 153.619 152.244 145.000 1.00 100.59 ? 129 LEU C CD1 1 
ATOM 4826 C CD2 . LEU C 1 55  ? 154.608 153.752 143.263 1.00 101.69 ? 129 LEU C CD2 1 
ATOM 4827 N N   . MET C 1 56  ? 157.769 155.029 147.451 1.00 99.76  ? 130 MET C N   1 
ATOM 4828 C CA  . MET C 1 56  ? 158.201 155.918 148.522 1.00 103.29 ? 130 MET C CA  1 
ATOM 4829 C C   . MET C 1 56  ? 159.394 156.770 148.110 1.00 103.51 ? 130 MET C C   1 
ATOM 4830 O O   . MET C 1 56  ? 159.631 157.819 148.718 1.00 104.55 ? 130 MET C O   1 
ATOM 4831 C CB  . MET C 1 56  ? 158.539 155.105 149.773 1.00 103.94 ? 130 MET C CB  1 
ATOM 4832 C CG  . MET C 1 56  ? 158.667 155.930 151.042 1.00 103.67 ? 130 MET C CG  1 
ATOM 4833 S SD  . MET C 1 56  ? 157.077 156.574 151.596 1.00 108.90 ? 130 MET C SD  1 
ATOM 4834 C CE  . MET C 1 56  ? 156.206 155.052 151.958 1.00 100.79 ? 130 MET C CE  1 
ATOM 4835 N N   . GLU C 1 57  ? 160.145 156.344 147.090 1.00 102.74 ? 131 GLU C N   1 
ATOM 4836 C CA  . GLU C 1 57  ? 161.277 157.138 146.624 1.00 102.74 ? 131 GLU C CA  1 
ATOM 4837 C C   . GLU C 1 57  ? 160.819 158.490 146.096 1.00 103.48 ? 131 GLU C C   1 
ATOM 4838 O O   . GLU C 1 57  ? 161.437 159.521 146.386 1.00 105.09 ? 131 GLU C O   1 
ATOM 4839 C CB  . GLU C 1 57  ? 162.047 156.370 145.550 1.00 103.99 ? 131 GLU C CB  1 
ATOM 4840 C CG  . GLU C 1 57  ? 163.289 157.081 145.048 1.00 105.78 ? 131 GLU C CG  1 
ATOM 4841 C CD  . GLU C 1 57  ? 164.021 156.288 143.984 1.00 106.03 ? 131 GLU C CD  1 
ATOM 4842 O OE1 . GLU C 1 57  ? 163.638 155.125 143.738 1.00 104.25 ? 131 GLU C OE1 1 
ATOM 4843 O OE2 . GLU C 1 57  ? 164.980 156.827 143.393 1.00 105.48 ? 131 GLU C OE2 1 
ATOM 4844 N N   . GLU C 1 58  ? 159.739 158.508 145.322 1.00 105.86 ? 132 GLU C N   1 
ATOM 4845 C CA  . GLU C 1 58  ? 159.155 159.765 144.891 1.00 106.43 ? 132 GLU C CA  1 
ATOM 4846 C C   . GLU C 1 58  ? 158.400 160.417 146.046 1.00 109.68 ? 132 GLU C C   1 
ATOM 4847 O O   . GLU C 1 58  ? 157.990 159.759 147.006 1.00 111.97 ? 132 GLU C O   1 
ATOM 4848 C CB  . GLU C 1 58  ? 158.218 159.547 143.703 1.00 106.94 ? 132 GLU C CB  1 
ATOM 4849 C CG  . GLU C 1 58  ? 158.877 158.874 142.510 1.00 108.95 ? 132 GLU C CG  1 
ATOM 4850 C CD  . GLU C 1 58  ? 157.901 158.596 141.383 1.00 110.51 ? 132 GLU C CD  1 
ATOM 4851 O OE1 . GLU C 1 58  ? 156.712 158.952 141.521 1.00 111.68 ? 132 GLU C OE1 1 
ATOM 4852 O OE2 . GLU C 1 58  ? 158.323 158.020 140.358 1.00 109.03 ? 132 GLU C OE2 1 
ATOM 4853 N N   . ASN C 1 59  ? 158.220 161.734 145.943 1.00 115.68 ? 133 ASN C N   1 
ATOM 4854 C CA  . ASN C 1 59  ? 157.524 162.503 146.976 1.00 114.99 ? 133 ASN C CA  1 
ATOM 4855 C C   . ASN C 1 59  ? 156.020 162.240 146.873 1.00 115.35 ? 133 ASN C C   1 
ATOM 4856 O O   . ASN C 1 59  ? 155.219 163.097 146.494 1.00 116.38 ? 133 ASN C O   1 
ATOM 4857 C CB  . ASN C 1 59  ? 157.852 163.985 146.852 1.00 115.52 ? 133 ASN C CB  1 
ATOM 4858 C CG  . ASN C 1 59  ? 157.754 164.489 145.424 1.00 118.37 ? 133 ASN C CG  1 
ATOM 4859 O OD1 . ASN C 1 59  ? 157.189 163.826 144.554 1.00 118.70 ? 133 ASN C OD1 1 
ATOM 4860 N ND2 . ASN C 1 59  ? 158.307 165.671 145.176 1.00 117.42 ? 133 ASN C ND2 1 
ATOM 4861 N N   . MET C 1 60  ? 155.643 161.014 147.229 1.00 100.54 ? 134 MET C N   1 
ATOM 4862 C CA  . MET C 1 60  ? 154.263 160.565 147.122 1.00 100.09 ? 134 MET C CA  1 
ATOM 4863 C C   . MET C 1 60  ? 153.890 159.797 148.380 1.00 97.81  ? 134 MET C C   1 
ATOM 4864 O O   . MET C 1 60  ? 154.566 158.828 148.740 1.00 95.82  ? 134 MET C O   1 
ATOM 4865 C CB  . MET C 1 60  ? 154.069 159.684 145.882 1.00 97.48  ? 134 MET C CB  1 
ATOM 4866 C CG  . MET C 1 60  ? 152.628 159.531 145.436 1.00 93.13  ? 134 MET C CG  1 
ATOM 4867 S SD  . MET C 1 60  ? 152.505 159.069 143.699 1.00 100.30 ? 134 MET C SD  1 
ATOM 4868 C CE  . MET C 1 60  ? 153.393 160.417 142.927 1.00 97.43  ? 134 MET C CE  1 
ATOM 4869 N N   . ILE C 1 61  ? 152.819 160.230 149.044 1.00 90.05  ? 135 ILE C N   1 
ATOM 4870 C CA  . ILE C 1 61  ? 152.344 159.539 150.237 1.00 87.63  ? 135 ILE C CA  1 
ATOM 4871 C C   . ILE C 1 61  ? 151.764 158.191 149.837 1.00 85.79  ? 135 ILE C C   1 
ATOM 4872 O O   . ILE C 1 61  ? 150.977 158.092 148.887 1.00 90.53  ? 135 ILE C O   1 
ATOM 4873 C CB  . ILE C 1 61  ? 151.309 160.396 150.980 1.00 88.29  ? 135 ILE C CB  1 
ATOM 4874 C CG1 . ILE C 1 61  ? 151.886 161.780 151.288 1.00 88.99  ? 135 ILE C CG1 1 
ATOM 4875 C CG2 . ILE C 1 61  ? 150.862 159.705 152.259 1.00 85.61  ? 135 ILE C CG2 1 
ATOM 4876 C CD1 . ILE C 1 61  ? 153.110 161.746 152.178 1.00 85.12  ? 135 ILE C CD1 1 
ATOM 4877 N N   . VAL C 1 62  ? 152.152 157.143 150.557 1.00 64.33  ? 136 VAL C N   1 
ATOM 4878 C CA  . VAL C 1 62  ? 151.739 155.779 150.255 1.00 62.86  ? 136 VAL C CA  1 
ATOM 4879 C C   . VAL C 1 62  ? 150.805 155.294 151.352 1.00 66.97  ? 136 VAL C C   1 
ATOM 4880 O O   . VAL C 1 62  ? 151.155 155.329 152.538 1.00 74.09  ? 136 VAL C O   1 
ATOM 4881 C CB  . VAL C 1 62  ? 152.949 154.841 150.114 1.00 67.45  ? 136 VAL C CB  1 
ATOM 4882 C CG1 . VAL C 1 62  ? 152.484 153.419 149.855 1.00 71.07  ? 136 VAL C CG1 1 
ATOM 4883 C CG2 . VAL C 1 62  ? 153.859 155.320 148.996 1.00 70.19  ? 136 VAL C CG2 1 
ATOM 4884 N N   . TYR C 1 63  ? 149.621 154.841 150.955 1.00 66.29  ? 137 TYR C N   1 
ATOM 4885 C CA  . TYR C 1 63  ? 148.658 154.233 151.861 1.00 54.81  ? 137 TYR C CA  1 
ATOM 4886 C C   . TYR C 1 63  ? 148.668 152.727 151.650 1.00 56.69  ? 137 TYR C C   1 
ATOM 4887 O O   . TYR C 1 63  ? 148.629 152.255 150.510 1.00 76.05  ? 137 TYR C O   1 
ATOM 4888 C CB  . TYR C 1 63  ? 147.252 154.780 151.619 1.00 66.04  ? 137 TYR C CB  1 
ATOM 4889 C CG  . TYR C 1 63  ? 146.957 156.097 152.294 1.00 66.63  ? 137 TYR C CG  1 
ATOM 4890 C CD1 . TYR C 1 63  ? 147.641 157.250 151.939 1.00 69.92  ? 137 TYR C CD1 1 
ATOM 4891 C CD2 . TYR C 1 63  ? 145.980 156.190 153.273 1.00 64.07  ? 137 TYR C CD2 1 
ATOM 4892 C CE1 . TYR C 1 63  ? 147.368 158.458 152.551 1.00 72.06  ? 137 TYR C CE1 1 
ATOM 4893 C CE2 . TYR C 1 63  ? 145.699 157.390 153.890 1.00 66.53  ? 137 TYR C CE2 1 
ATOM 4894 C CZ  . TYR C 1 63  ? 146.396 158.522 153.527 1.00 72.37  ? 137 TYR C CZ  1 
ATOM 4895 O OH  . TYR C 1 63  ? 146.119 159.722 154.141 1.00 75.98  ? 137 TYR C OH  1 
ATOM 4896 N N   . VAL C 1 64  ? 148.734 151.980 152.743 1.00 44.91  ? 138 VAL C N   1 
ATOM 4897 C CA  . VAL C 1 64  ? 148.640 150.527 152.710 1.00 56.93  ? 138 VAL C CA  1 
ATOM 4898 C C   . VAL C 1 64  ? 147.674 150.112 153.809 1.00 64.66  ? 138 VAL C C   1 
ATOM 4899 O O   . VAL C 1 64  ? 147.587 150.774 154.849 1.00 68.89  ? 138 VAL C O   1 
ATOM 4900 C CB  . VAL C 1 64  ? 150.023 149.861 152.887 1.00 67.73  ? 138 VAL C CB  1 
ATOM 4901 C CG1 . VAL C 1 64  ? 149.904 148.344 152.949 1.00 69.94  ? 138 VAL C CG1 1 
ATOM 4902 C CG2 . VAL C 1 64  ? 150.959 150.269 151.760 1.00 62.74  ? 138 VAL C CG2 1 
ATOM 4903 N N   . GLU C 1 65  ? 146.929 149.034 153.570 1.00 74.19  ? 139 GLU C N   1 
ATOM 4904 C CA  . GLU C 1 65  ? 145.980 148.550 154.563 1.00 75.51  ? 139 GLU C CA  1 
ATOM 4905 C C   . GLU C 1 65  ? 146.689 148.273 155.882 1.00 76.94  ? 139 GLU C C   1 
ATOM 4906 O O   . GLU C 1 65  ? 147.776 147.689 155.913 1.00 79.56  ? 139 GLU C O   1 
ATOM 4907 C CB  . GLU C 1 65  ? 145.282 147.287 154.059 1.00 73.25  ? 139 GLU C CB  1 
ATOM 4908 C CG  . GLU C 1 65  ? 144.039 146.908 154.845 1.00 74.30  ? 139 GLU C CG  1 
ATOM 4909 C CD  . GLU C 1 65  ? 142.888 147.873 154.625 1.00 81.24  ? 139 GLU C CD  1 
ATOM 4910 O OE1 . GLU C 1 65  ? 142.899 148.596 153.606 1.00 80.53  ? 139 GLU C OE1 1 
ATOM 4911 O OE2 . GLU C 1 65  ? 141.972 147.908 155.473 1.00 82.42  ? 139 GLU C OE2 1 
ATOM 4912 N N   . LYS C 1 66  ? 146.066 148.710 156.980 1.00 69.83  ? 140 LYS C N   1 
ATOM 4913 C CA  . LYS C 1 66  ? 146.713 148.629 158.286 1.00 67.67  ? 140 LYS C CA  1 
ATOM 4914 C C   . LYS C 1 66  ? 146.987 147.189 158.698 1.00 62.44  ? 140 LYS C C   1 
ATOM 4915 O O   . LYS C 1 66  ? 147.943 146.929 159.438 1.00 64.08  ? 140 LYS C O   1 
ATOM 4916 C CB  . LYS C 1 66  ? 145.856 149.337 159.337 1.00 67.96  ? 140 LYS C CB  1 
ATOM 4917 C CG  . LYS C 1 66  ? 144.518 148.671 159.617 1.00 68.43  ? 140 LYS C CG  1 
ATOM 4918 C CD  . LYS C 1 66  ? 143.718 149.450 160.648 1.00 61.04  ? 140 LYS C CD  1 
ATOM 4919 C CE  . LYS C 1 66  ? 142.361 148.811 160.893 1.00 60.56  ? 140 LYS C CE  1 
ATOM 4920 N NZ  . LYS C 1 66  ? 142.483 147.479 161.549 1.00 63.76  ? 140 LYS C NZ  1 
ATOM 4921 N N   . LYS C 1 67  ? 146.173 146.243 158.235 1.00 72.76  ? 141 LYS C N   1 
ATOM 4922 C CA  . LYS C 1 67  ? 146.393 144.842 158.566 1.00 75.88  ? 141 LYS C CA  1 
ATOM 4923 C C   . LYS C 1 67  ? 147.421 144.174 157.664 1.00 73.98  ? 141 LYS C C   1 
ATOM 4924 O O   . LYS C 1 67  ? 147.841 143.050 157.960 1.00 73.61  ? 141 LYS C O   1 
ATOM 4925 C CB  . LYS C 1 67  ? 145.072 144.072 158.504 1.00 79.39  ? 141 LYS C CB  1 
ATOM 4926 C CG  . LYS C 1 67  ? 144.484 143.948 157.110 1.00 79.71  ? 141 LYS C CG  1 
ATOM 4927 C CD  . LYS C 1 67  ? 143.163 143.196 157.138 1.00 78.96  ? 141 LYS C CD  1 
ATOM 4928 C CE  . LYS C 1 67  ? 142.548 143.107 155.751 1.00 77.56  ? 141 LYS C CE  1 
ATOM 4929 N NZ  . LYS C 1 67  ? 143.365 142.261 154.837 1.00 76.65  ? 141 LYS C NZ  1 
ATOM 4930 N N   . VAL C 1 68  ? 147.830 144.824 156.573 1.00 78.65  ? 142 VAL C N   1 
ATOM 4931 C CA  . VAL C 1 68  ? 148.868 144.251 155.723 1.00 78.04  ? 142 VAL C CA  1 
ATOM 4932 C C   . VAL C 1 68  ? 150.215 144.289 156.430 1.00 79.61  ? 142 VAL C C   1 
ATOM 4933 O O   . VAL C 1 68  ? 150.953 143.297 156.445 1.00 82.44  ? 142 VAL C O   1 
ATOM 4934 C CB  . VAL C 1 68  ? 148.918 144.980 154.369 1.00 82.94  ? 142 VAL C CB  1 
ATOM 4935 C CG1 . VAL C 1 68  ? 150.180 144.603 153.607 1.00 83.67  ? 142 VAL C CG1 1 
ATOM 4936 C CG2 . VAL C 1 68  ? 147.680 144.660 153.549 1.00 83.26  ? 142 VAL C CG2 1 
ATOM 4937 N N   . LEU C 1 69  ? 150.555 145.425 157.038 1.00 86.81  ? 143 LEU C N   1 
ATOM 4938 C CA  . LEU C 1 69  ? 151.831 145.576 157.735 1.00 88.53  ? 143 LEU C CA  1 
ATOM 4939 C C   . LEU C 1 69  ? 151.809 145.037 159.164 1.00 90.75  ? 143 LEU C C   1 
ATOM 4940 O O   . LEU C 1 69  ? 152.276 145.689 160.099 1.00 90.39  ? 143 LEU C O   1 
ATOM 4941 C CB  . LEU C 1 69  ? 152.237 147.051 157.684 1.00 89.12  ? 143 LEU C CB  1 
ATOM 4942 C CG  . LEU C 1 69  ? 151.333 148.186 158.203 1.00 89.00  ? 143 LEU C CG  1 
ATOM 4943 C CD1 . LEU C 1 69  ? 151.462 148.498 159.692 1.00 89.67  ? 143 LEU C CD1 1 
ATOM 4944 C CD2 . LEU C 1 69  ? 151.561 149.449 157.378 1.00 85.61  ? 143 LEU C CD2 1 
ATOM 4945 N N   . GLU C 1 70  ? 151.325 143.807 159.345 1.00 91.75  ? 144 GLU C N   1 
ATOM 4946 C CA  . GLU C 1 70  ? 151.386 143.153 160.645 1.00 86.65  ? 144 GLU C CA  1 
ATOM 4947 C C   . GLU C 1 70  ? 151.604 141.651 160.522 1.00 86.36  ? 144 GLU C C   1 
ATOM 4948 O O   . GLU C 1 70  ? 151.553 140.948 161.539 1.00 88.33  ? 144 GLU C O   1 
ATOM 4949 C CB  . GLU C 1 70  ? 150.116 143.424 161.461 1.00 88.65  ? 144 GLU C CB  1 
ATOM 4950 C CG  . GLU C 1 70  ? 148.875 142.717 160.947 1.00 93.09  ? 144 GLU C CG  1 
ATOM 4951 C CD  . GLU C 1 70  ? 147.647 143.019 161.784 1.00 94.74  ? 144 GLU C CD  1 
ATOM 4952 O OE1 . GLU C 1 70  ? 147.778 143.753 162.786 1.00 91.68  ? 144 GLU C OE1 1 
ATOM 4953 O OE2 . GLU C 1 70  ? 146.553 142.523 161.442 1.00 96.80  ? 144 GLU C OE2 1 
ATOM 4954 N N   . ASP C 1 71  ? 151.834 141.138 159.319 1.00 97.09  ? 145 ASP C N   1 
ATOM 4955 C CA  . ASP C 1 71  ? 152.063 139.713 159.151 1.00 98.29  ? 145 ASP C CA  1 
ATOM 4956 C C   . ASP C 1 71  ? 153.413 139.328 159.750 1.00 99.36  ? 145 ASP C C   1 
ATOM 4957 O O   . ASP C 1 71  ? 154.341 140.146 159.768 1.00 100.62 ? 145 ASP C O   1 
ATOM 4958 C CB  . ASP C 1 71  ? 152.020 139.332 157.671 1.00 98.06  ? 145 ASP C CB  1 
ATOM 4959 C CG  . ASP C 1 71  ? 150.709 139.703 157.011 1.00 99.12  ? 145 ASP C CG  1 
ATOM 4960 O OD1 . ASP C 1 71  ? 149.791 140.162 157.724 1.00 100.20 ? 145 ASP C OD1 1 
ATOM 4961 O OD2 . ASP C 1 71  ? 150.595 139.535 155.779 1.00 99.64  ? 145 ASP C OD2 1 
ATOM 4962 N N   . PRO C 1 72  ? 153.555 138.103 160.261 1.00 109.54 ? 146 PRO C N   1 
ATOM 4963 C CA  . PRO C 1 72  ? 154.873 137.669 160.749 1.00 109.33 ? 146 PRO C CA  1 
ATOM 4964 C C   . PRO C 1 72  ? 155.945 137.691 159.675 1.00 106.88 ? 146 PRO C C   1 
ATOM 4965 O O   . PRO C 1 72  ? 157.115 137.949 159.986 1.00 107.95 ? 146 PRO C O   1 
ATOM 4966 C CB  . PRO C 1 72  ? 154.608 136.243 161.256 1.00 110.62 ? 146 PRO C CB  1 
ATOM 4967 C CG  . PRO C 1 72  ? 153.338 135.819 160.580 1.00 110.47 ? 146 PRO C CG  1 
ATOM 4968 C CD  . PRO C 1 72  ? 152.527 137.067 160.446 1.00 109.33 ? 146 PRO C CD  1 
ATOM 4969 N N   . ALA C 1 73  ? 155.582 137.422 158.419 1.00 99.71  ? 147 ALA C N   1 
ATOM 4970 C CA  . ALA C 1 73  ? 156.568 137.434 157.343 1.00 102.04 ? 147 ALA C CA  1 
ATOM 4971 C C   . ALA C 1 73  ? 157.141 138.829 157.125 1.00 103.08 ? 147 ALA C C   1 
ATOM 4972 O O   . ALA C 1 73  ? 158.353 138.984 156.934 1.00 100.20 ? 147 ALA C O   1 
ATOM 4973 C CB  . ALA C 1 73  ? 155.942 136.903 156.054 1.00 102.99 ? 147 ALA C CB  1 
ATOM 4974 N N   . ILE C 1 74  ? 156.290 139.856 157.147 1.00 106.92 ? 148 ILE C N   1 
ATOM 4975 C CA  . ILE C 1 74  ? 156.779 141.212 156.920 1.00 105.16 ? 148 ILE C CA  1 
ATOM 4976 C C   . ILE C 1 74  ? 157.424 141.782 158.180 1.00 105.76 ? 148 ILE C C   1 
ATOM 4977 O O   . ILE C 1 74  ? 158.294 142.656 158.093 1.00 107.13 ? 148 ILE C O   1 
ATOM 4978 C CB  . ILE C 1 74  ? 155.643 142.113 156.403 1.00 104.70 ? 148 ILE C CB  1 
ATOM 4979 C CG1 . ILE C 1 74  ? 156.216 143.353 155.712 1.00 106.64 ? 148 ILE C CG1 1 
ATOM 4980 C CG2 . ILE C 1 74  ? 154.701 142.513 157.530 1.00 101.18 ? 148 ILE C CG2 1 
ATOM 4981 C CD1 . ILE C 1 74  ? 155.161 144.291 155.166 1.00 107.08 ? 148 ILE C CD1 1 
ATOM 4982 N N   . ALA C 1 75  ? 157.021 141.307 159.361 1.00 111.20 ? 149 ALA C N   1 
ATOM 4983 C CA  . ALA C 1 75  ? 157.641 141.767 160.597 1.00 111.74 ? 149 ALA C CA  1 
ATOM 4984 C C   . ALA C 1 75  ? 159.000 141.121 160.832 1.00 113.30 ? 149 ALA C C   1 
ATOM 4985 O O   . ALA C 1 75  ? 159.904 141.771 161.370 1.00 111.70 ? 149 ALA C O   1 
ATOM 4986 C CB  . ALA C 1 75  ? 156.717 141.490 161.784 1.00 112.85 ? 149 ALA C CB  1 
ATOM 4987 N N   . SER C 1 76  ? 159.162 139.853 160.445 1.00 120.78 ? 150 SER C N   1 
ATOM 4988 C CA  . SER C 1 76  ? 160.422 139.156 160.683 1.00 119.59 ? 150 SER C CA  1 
ATOM 4989 C C   . SER C 1 76  ? 161.566 139.786 159.899 1.00 118.98 ? 150 SER C C   1 
ATOM 4990 O O   . SER C 1 76  ? 162.679 139.925 160.420 1.00 117.94 ? 150 SER C O   1 
ATOM 4991 C CB  . SER C 1 76  ? 160.280 137.676 160.325 1.00 119.15 ? 150 SER C CB  1 
ATOM 4992 O OG  . SER C 1 76  ? 159.254 137.063 161.087 1.00 118.77 ? 150 SER C OG  1 
ATOM 4993 N N   . ASP C 1 77  ? 161.317 140.169 158.650 1.00 122.87 ? 151 ASP C N   1 
ATOM 4994 C CA  . ASP C 1 77  ? 162.354 140.753 157.802 1.00 124.67 ? 151 ASP C CA  1 
ATOM 4995 C C   . ASP C 1 77  ? 162.651 142.163 158.295 1.00 124.46 ? 151 ASP C C   1 
ATOM 4996 O O   . ASP C 1 77  ? 161.898 143.102 158.028 1.00 124.52 ? 151 ASP C O   1 
ATOM 4997 C CB  . ASP C 1 77  ? 161.907 140.756 156.344 1.00 122.78 ? 151 ASP C CB  1 
ATOM 4998 C CG  . ASP C 1 77  ? 163.060 140.955 155.376 1.00 122.28 ? 151 ASP C CG  1 
ATOM 4999 O OD1 . ASP C 1 77  ? 164.018 141.678 155.719 1.00 120.96 ? 151 ASP C OD1 1 
ATOM 5000 O OD2 . ASP C 1 77  ? 163.008 140.385 154.266 1.00 122.62 ? 151 ASP C OD2 1 
ATOM 5001 N N   . GLU C 1 78  ? 163.759 142.317 159.021 1.00 121.51 ? 152 GLU C N   1 
ATOM 5002 C CA  . GLU C 1 78  ? 164.142 143.622 159.545 1.00 121.36 ? 152 GLU C CA  1 
ATOM 5003 C C   . GLU C 1 78  ? 164.679 144.552 158.466 1.00 119.12 ? 152 GLU C C   1 
ATOM 5004 O O   . GLU C 1 78  ? 164.713 145.769 158.680 1.00 118.96 ? 152 GLU C O   1 
ATOM 5005 C CB  . GLU C 1 78  ? 165.190 143.468 160.652 1.00 121.63 ? 152 GLU C CB  1 
ATOM 5006 C CG  . GLU C 1 78  ? 166.488 142.800 160.212 1.00 120.63 ? 152 GLU C CG  1 
ATOM 5007 C CD  . GLU C 1 78  ? 166.399 141.286 160.196 1.00 121.27 ? 152 GLU C CD  1 
ATOM 5008 O OE1 . GLU C 1 78  ? 165.377 140.743 160.663 1.00 122.28 ? 152 GLU C OE1 1 
ATOM 5009 O OE2 . GLU C 1 78  ? 167.353 140.639 159.715 1.00 120.38 ? 152 GLU C OE2 1 
ATOM 5010 N N   . SER C 1 79  ? 165.102 144.011 157.322 1.00 105.78 ? 153 SER C N   1 
ATOM 5011 C CA  . SER C 1 79  ? 165.627 144.858 156.256 1.00 106.12 ? 153 SER C CA  1 
ATOM 5012 C C   . SER C 1 79  ? 164.554 145.793 155.714 1.00 107.79 ? 153 SER C C   1 
ATOM 5013 O O   . SER C 1 79  ? 164.819 146.974 155.461 1.00 106.53 ? 153 SER C O   1 
ATOM 5014 C CB  . SER C 1 79  ? 166.203 143.994 155.135 1.00 106.10 ? 153 SER C CB  1 
ATOM 5015 O OG  . SER C 1 79  ? 166.714 144.798 154.086 1.00 108.05 ? 153 SER C OG  1 
ATOM 5016 N N   . PHE C 1 80  ? 163.335 145.285 155.534 1.00 107.09 ? 154 PHE C N   1 
ATOM 5017 C CA  . PHE C 1 80  ? 162.243 146.101 155.020 1.00 106.62 ? 154 PHE C CA  1 
ATOM 5018 C C   . PHE C 1 80  ? 161.645 147.025 156.071 1.00 104.67 ? 154 PHE C C   1 
ATOM 5019 O O   . PHE C 1 80  ? 160.840 147.895 155.721 1.00 104.58 ? 154 PHE C O   1 
ATOM 5020 C CB  . PHE C 1 80  ? 161.148 145.204 154.435 1.00 103.58 ? 154 PHE C CB  1 
ATOM 5021 C CG  . PHE C 1 80  ? 160.120 145.950 153.635 1.00 105.44 ? 154 PHE C CG  1 
ATOM 5022 C CD1 . PHE C 1 80  ? 160.444 146.492 152.403 1.00 105.98 ? 154 PHE C CD1 1 
ATOM 5023 C CD2 . PHE C 1 80  ? 158.829 146.103 154.110 1.00 105.79 ? 154 PHE C CD2 1 
ATOM 5024 C CE1 . PHE C 1 80  ? 159.502 147.179 151.663 1.00 107.46 ? 154 PHE C CE1 1 
ATOM 5025 C CE2 . PHE C 1 80  ? 157.881 146.788 153.374 1.00 104.09 ? 154 PHE C CE2 1 
ATOM 5026 C CZ  . PHE C 1 80  ? 158.218 147.326 152.149 1.00 105.59 ? 154 PHE C CZ  1 
ATOM 5027 N N   . GLY C 1 81  ? 162.024 146.872 157.341 1.00 96.74  ? 155 GLY C N   1 
ATOM 5028 C CA  . GLY C 1 81  ? 161.498 147.739 158.379 1.00 97.81  ? 155 GLY C CA  1 
ATOM 5029 C C   . GLY C 1 81  ? 161.904 149.189 158.237 1.00 96.99  ? 155 GLY C C   1 
ATOM 5030 O O   . GLY C 1 81  ? 161.315 150.053 158.895 1.00 98.54  ? 155 GLY C O   1 
ATOM 5031 N N   . ALA C 1 82  ? 162.902 149.475 157.398 1.00 87.07  ? 156 ALA C N   1 
ATOM 5032 C CA  . ALA C 1 82  ? 163.338 150.854 157.209 1.00 89.87  ? 156 ALA C CA  1 
ATOM 5033 C C   . ALA C 1 82  ? 162.229 151.711 156.614 1.00 91.59  ? 156 ALA C C   1 
ATOM 5034 O O   . ALA C 1 82  ? 162.010 152.847 157.050 1.00 94.18  ? 156 ALA C O   1 
ATOM 5035 C CB  . ALA C 1 82  ? 164.581 150.894 156.320 1.00 91.38  ? 156 ALA C CB  1 
ATOM 5036 N N   . VAL C 1 83  ? 161.512 151.182 155.618 1.00 95.32  ? 157 VAL C N   1 
ATOM 5037 C CA  . VAL C 1 83  ? 160.453 151.943 154.962 1.00 97.56  ? 157 VAL C CA  1 
ATOM 5038 C C   . VAL C 1 83  ? 159.066 151.611 155.492 1.00 94.63  ? 157 VAL C C   1 
ATOM 5039 O O   . VAL C 1 83  ? 158.090 152.262 155.087 1.00 94.39  ? 157 VAL C O   1 
ATOM 5040 C CB  . VAL C 1 83  ? 160.479 151.720 153.438 1.00 99.16  ? 157 VAL C CB  1 
ATOM 5041 C CG1 . VAL C 1 83  ? 161.792 152.218 152.853 1.00 96.95  ? 157 VAL C CG1 1 
ATOM 5042 C CG2 . VAL C 1 83  ? 160.272 150.252 153.117 1.00 98.12  ? 157 VAL C CG2 1 
ATOM 5043 N N   . LYS C 1 84  ? 158.943 150.621 156.379 1.00 90.98  ? 158 LYS C N   1 
ATOM 5044 C CA  . LYS C 1 84  ? 157.635 150.279 156.930 1.00 92.76  ? 158 LYS C CA  1 
ATOM 5045 C C   . LYS C 1 84  ? 157.046 151.442 157.717 1.00 93.47  ? 158 LYS C C   1 
ATOM 5046 O O   . LYS C 1 84  ? 155.830 151.667 157.691 1.00 95.53  ? 158 LYS C O   1 
ATOM 5047 C CB  . LYS C 1 84  ? 157.744 149.037 157.814 1.00 95.36  ? 158 LYS C CB  1 
ATOM 5048 C CG  . LYS C 1 84  ? 157.774 147.728 157.045 1.00 96.29  ? 158 LYS C CG  1 
ATOM 5049 C CD  . LYS C 1 84  ? 157.998 146.541 157.969 1.00 96.00  ? 158 LYS C CD  1 
ATOM 5050 C CE  . LYS C 1 84  ? 156.888 146.423 159.002 1.00 95.69  ? 158 LYS C CE  1 
ATOM 5051 N NZ  . LYS C 1 84  ? 157.102 145.268 159.918 1.00 96.02  ? 158 LYS C NZ  1 
ATOM 5052 N N   . LYS C 1 85  ? 157.893 152.191 158.426 1.00 100.92 ? 159 LYS C N   1 
ATOM 5053 C CA  . LYS C 1 85  ? 157.417 153.315 159.222 1.00 103.59 ? 159 LYS C CA  1 
ATOM 5054 C C   . LYS C 1 85  ? 156.818 154.419 158.361 1.00 101.87 ? 159 LYS C C   1 
ATOM 5055 O O   . LYS C 1 85  ? 155.972 155.179 158.845 1.00 102.47 ? 159 LYS C O   1 
ATOM 5056 C CB  . LYS C 1 85  ? 158.567 153.862 160.076 1.00 103.33 ? 159 LYS C CB  1 
ATOM 5057 C CG  . LYS C 1 85  ? 158.195 154.998 161.022 1.00 102.70 ? 159 LYS C CG  1 
ATOM 5058 C CD  . LYS C 1 85  ? 158.606 156.353 160.462 1.00 102.49 ? 159 LYS C CD  1 
ATOM 5059 C CE  . LYS C 1 85  ? 158.155 157.488 161.367 1.00 102.34 ? 159 LYS C CE  1 
ATOM 5060 N NZ  . LYS C 1 85  ? 158.518 158.821 160.810 1.00 101.74 ? 159 LYS C NZ  1 
ATOM 5061 N N   . LYS C 1 86  ? 157.216 154.514 157.094 1.00 88.55  ? 160 LYS C N   1 
ATOM 5062 C CA  . LYS C 1 86  ? 156.767 155.602 156.235 1.00 91.04  ? 160 LYS C CA  1 
ATOM 5063 C C   . LYS C 1 86  ? 155.406 155.347 155.599 1.00 95.40  ? 160 LYS C C   1 
ATOM 5064 O O   . LYS C 1 86  ? 154.913 156.213 154.869 1.00 96.78  ? 160 LYS C O   1 
ATOM 5065 C CB  . LYS C 1 86  ? 157.807 155.870 155.145 1.00 91.13  ? 160 LYS C CB  1 
ATOM 5066 C CG  . LYS C 1 86  ? 159.226 156.003 155.670 1.00 90.69  ? 160 LYS C CG  1 
ATOM 5067 C CD  . LYS C 1 86  ? 160.197 156.338 154.552 1.00 91.17  ? 160 LYS C CD  1 
ATOM 5068 C CE  . LYS C 1 86  ? 159.952 157.739 154.018 1.00 92.17  ? 160 LYS C CE  1 
ATOM 5069 N NZ  . LYS C 1 86  ? 160.891 158.084 152.915 1.00 91.18  ? 160 LYS C NZ  1 
ATOM 5070 N N   . PHE C 1 87  ? 154.789 154.194 155.851 1.00 74.95  ? 161 PHE C N   1 
ATOM 5071 C CA  . PHE C 1 87  ? 153.452 153.935 155.340 1.00 59.32  ? 161 PHE C CA  1 
ATOM 5072 C C   . PHE C 1 87  ? 152.423 154.792 156.073 1.00 62.10  ? 161 PHE C C   1 
ATOM 5073 O O   . PHE C 1 87  ? 152.741 155.533 157.007 1.00 70.98  ? 161 PHE C O   1 
ATOM 5074 C CB  . PHE C 1 87  ? 153.094 152.456 155.488 1.00 59.17  ? 161 PHE C CB  1 
ATOM 5075 C CG  . PHE C 1 87  ? 153.875 151.548 154.586 1.00 67.78  ? 161 PHE C CG  1 
ATOM 5076 C CD1 . PHE C 1 87  ? 154.481 152.037 153.442 1.00 74.57  ? 161 PHE C CD1 1 
ATOM 5077 C CD2 . PHE C 1 87  ? 154.000 150.201 154.880 1.00 69.49  ? 161 PHE C CD2 1 
ATOM 5078 C CE1 . PHE C 1 87  ? 155.199 151.200 152.609 1.00 73.94  ? 161 PHE C CE1 1 
ATOM 5079 C CE2 . PHE C 1 87  ? 154.715 149.360 154.054 1.00 69.93  ? 161 PHE C CE2 1 
ATOM 5080 C CZ  . PHE C 1 87  ? 155.316 149.859 152.916 1.00 71.55  ? 161 PHE C CZ  1 
ATOM 5081 N N   . THR C 1 88  ? 151.174 154.683 155.636 1.00 55.32  ? 162 THR C N   1 
ATOM 5082 C CA  . THR C 1 88  ? 150.084 155.411 156.275 1.00 60.01  ? 162 THR C CA  1 
ATOM 5083 C C   . THR C 1 88  ? 148.822 154.558 156.351 1.00 60.19  ? 162 THR C C   1 
ATOM 5084 O O   . THR C 1 88  ? 148.458 154.061 157.417 1.00 57.60  ? 162 THR C O   1 
ATOM 5085 C CB  . THR C 1 88  ? 149.793 156.721 155.519 1.00 61.22  ? 162 THR C CB  1 
ATOM 5086 O OG1 . THR C 1 88  ? 150.955 157.556 155.539 1.00 62.70  ? 162 THR C OG1 1 
ATOM 5087 C CG2 . THR C 1 88  ? 148.755 157.547 156.264 1.00 57.12  ? 162 THR C CG2 1 
ATOM 5088 N N   . GLN C 1 100 ? 140.333 160.134 150.217 1.00 85.72  ? 174 GLN C N   1 
ATOM 5089 C CA  . GLN C 1 100 ? 141.692 160.658 150.256 1.00 91.40  ? 174 GLN C CA  1 
ATOM 5090 C C   . GLN C 1 100 ? 142.652 159.863 149.379 1.00 95.22  ? 174 GLN C C   1 
ATOM 5091 O O   . GLN C 1 100 ? 143.867 160.082 149.452 1.00 96.21  ? 174 GLN C O   1 
ATOM 5092 C CB  . GLN C 1 100 ? 142.208 160.691 151.698 1.00 91.44  ? 174 GLN C CB  1 
ATOM 5093 C CG  . GLN C 1 100 ? 142.411 159.318 152.320 1.00 92.59  ? 174 GLN C CG  1 
ATOM 5094 C CD  . GLN C 1 100 ? 141.200 158.847 153.102 1.00 94.15  ? 174 GLN C CD  1 
ATOM 5095 O OE1 . GLN C 1 100 ? 140.130 159.453 153.038 1.00 94.61  ? 174 GLN C OE1 1 
ATOM 5096 N NE2 . GLN C 1 100 ? 141.364 157.760 153.847 1.00 91.67  ? 174 GLN C NE2 1 
ATOM 5097 N N   . ILE C 1 101 ? 142.143 158.952 148.554 1.00 84.59  ? 175 ILE C N   1 
ATOM 5098 C CA  . ILE C 1 101 ? 142.966 158.130 147.673 1.00 81.73  ? 175 ILE C CA  1 
ATOM 5099 C C   . ILE C 1 101 ? 142.893 158.699 146.265 1.00 77.01  ? 175 ILE C C   1 
ATOM 5100 O O   . ILE C 1 101 ? 141.801 158.986 145.757 1.00 80.09  ? 175 ILE C O   1 
ATOM 5101 C CB  . ILE C 1 101 ? 142.513 156.661 147.697 1.00 80.49  ? 175 ILE C CB  1 
ATOM 5102 C CG1 . ILE C 1 101 ? 142.500 156.131 149.132 1.00 79.13  ? 175 ILE C CG1 1 
ATOM 5103 C CG2 . ILE C 1 101 ? 143.409 155.811 146.810 1.00 80.81  ? 175 ILE C CG2 1 
ATOM 5104 C CD1 . ILE C 1 101 ? 143.847 156.193 149.816 1.00 76.87  ? 175 ILE C CD1 1 
ATOM 5105 N N   . ASP C 1 102 ? 144.053 158.866 145.633 1.00 66.29  ? 176 ASP C N   1 
ATOM 5106 C CA  . ASP C 1 102 ? 144.122 159.407 144.283 1.00 71.14  ? 176 ASP C CA  1 
ATOM 5107 C C   . ASP C 1 102 ? 144.393 158.353 143.221 1.00 73.13  ? 176 ASP C C   1 
ATOM 5108 O O   . ASP C 1 102 ? 144.015 158.550 142.062 1.00 78.89  ? 176 ASP C O   1 
ATOM 5109 C CB  . ASP C 1 102 ? 145.207 160.486 144.199 1.00 76.91  ? 176 ASP C CB  1 
ATOM 5110 C CG  . ASP C 1 102 ? 144.870 161.713 145.018 1.00 79.95  ? 176 ASP C CG  1 
ATOM 5111 O OD1 . ASP C 1 102 ? 143.668 162.004 145.188 1.00 78.87  ? 176 ASP C OD1 1 
ATOM 5112 O OD2 . ASP C 1 102 ? 145.808 162.389 145.491 1.00 81.52  ? 176 ASP C OD2 1 
ATOM 5113 N N   . PHE C 1 103 ? 145.034 157.244 143.581 1.00 59.38  ? 177 PHE C N   1 
ATOM 5114 C CA  . PHE C 1 103 ? 145.375 156.219 142.605 1.00 59.60  ? 177 PHE C CA  1 
ATOM 5115 C C   . PHE C 1 103 ? 145.606 154.906 143.339 1.00 64.64  ? 177 PHE C C   1 
ATOM 5116 O O   . PHE C 1 103 ? 146.129 154.890 144.456 1.00 73.34  ? 177 PHE C O   1 
ATOM 5117 C CB  . PHE C 1 103 ? 146.610 156.625 141.793 1.00 63.52  ? 177 PHE C CB  1 
ATOM 5118 C CG  . PHE C 1 103 ? 147.098 155.565 140.853 1.00 65.47  ? 177 PHE C CG  1 
ATOM 5119 C CD1 . PHE C 1 103 ? 146.278 155.081 139.848 1.00 70.08  ? 177 PHE C CD1 1 
ATOM 5120 C CD2 . PHE C 1 103 ? 148.384 155.067 140.959 1.00 66.48  ? 177 PHE C CD2 1 
ATOM 5121 C CE1 . PHE C 1 103 ? 146.726 154.110 138.977 1.00 73.10  ? 177 PHE C CE1 1 
ATOM 5122 C CE2 . PHE C 1 103 ? 148.839 154.099 140.091 1.00 70.36  ? 177 PHE C CE2 1 
ATOM 5123 C CZ  . PHE C 1 103 ? 148.009 153.619 139.098 1.00 75.04  ? 177 PHE C CZ  1 
ATOM 5124 N N   . ILE C 1 104 ? 145.210 153.807 142.699 1.00 58.88  ? 178 ILE C N   1 
ATOM 5125 C CA  . ILE C 1 104 ? 145.212 152.485 143.314 1.00 57.03  ? 178 ILE C CA  1 
ATOM 5126 C C   . ILE C 1 104 ? 146.096 151.556 142.493 1.00 59.57  ? 178 ILE C C   1 
ATOM 5127 O O   . ILE C 1 104 ? 145.972 151.498 141.265 1.00 66.53  ? 178 ILE C O   1 
ATOM 5128 C CB  . ILE C 1 104 ? 143.787 151.915 143.430 1.00 51.57  ? 178 ILE C CB  1 
ATOM 5129 C CG1 . ILE C 1 104 ? 142.950 152.752 144.393 1.00 56.02  ? 178 ILE C CG1 1 
ATOM 5130 C CG2 . ILE C 1 104 ? 143.823 150.472 143.890 1.00 56.80  ? 178 ILE C CG2 1 
ATOM 5131 C CD1 . ILE C 1 104 ? 141.541 152.236 144.572 1.00 60.36  ? 178 ILE C CD1 1 
ATOM 5132 N N   . ILE C 1 105 ? 146.984 150.836 143.174 1.00 56.47  ? 179 ILE C N   1 
ATOM 5133 C CA  . ILE C 1 105 ? 147.802 149.789 142.573 1.00 49.10  ? 179 ILE C CA  1 
ATOM 5134 C C   . ILE C 1 105 ? 147.426 148.471 143.230 1.00 54.76  ? 179 ILE C C   1 
ATOM 5135 O O   . ILE C 1 105 ? 147.407 148.371 144.462 1.00 68.34  ? 179 ILE C O   1 
ATOM 5136 C CB  . ILE C 1 105 ? 149.306 150.069 142.739 1.00 61.12  ? 179 ILE C CB  1 
ATOM 5137 C CG1 . ILE C 1 105 ? 149.691 151.363 142.023 1.00 67.20  ? 179 ILE C CG1 1 
ATOM 5138 C CG2 . ILE C 1 105 ? 150.122 148.905 142.211 1.00 62.93  ? 179 ILE C CG2 1 
ATOM 5139 C CD1 . ILE C 1 105 ? 151.162 151.702 142.125 1.00 68.21  ? 179 ILE C CD1 1 
ATOM 5140 N N   . CYS C 1 106 ? 147.128 147.464 142.414 1.00 58.89  ? 180 CYS C N   1 
ATOM 5141 C CA  . CYS C 1 106 ? 146.633 146.183 142.897 1.00 60.14  ? 180 CYS C CA  1 
ATOM 5142 C C   . CYS C 1 106 ? 147.571 145.064 142.476 1.00 65.47  ? 180 CYS C C   1 
ATOM 5143 O O   . CYS C 1 106 ? 148.070 145.056 141.346 1.00 71.12  ? 180 CYS C O   1 
ATOM 5144 C CB  . CYS C 1 106 ? 145.221 145.911 142.375 1.00 67.43  ? 180 CYS C CB  1 
ATOM 5145 S SG  . CYS C 1 106 ? 143.931 146.871 143.193 1.00 83.79  ? 180 CYS C SG  1 
ATOM 5146 N N   . LEU C 1 107 ? 147.805 144.124 143.387 1.00 87.23  ? 181 LEU C N   1 
ATOM 5147 C CA  . LEU C 1 107 ? 148.593 142.929 143.124 1.00 89.46  ? 181 LEU C CA  1 
ATOM 5148 C C   . LEU C 1 107 ? 147.713 141.708 143.346 1.00 91.06  ? 181 LEU C C   1 
ATOM 5149 O O   . LEU C 1 107 ? 147.041 141.602 144.378 1.00 90.71  ? 181 LEU C O   1 
ATOM 5150 C CB  . LEU C 1 107 ? 149.824 142.872 144.031 1.00 88.66  ? 181 LEU C CB  1 
ATOM 5151 C CG  . LEU C 1 107 ? 150.793 144.051 143.929 1.00 88.18  ? 181 LEU C CG  1 
ATOM 5152 C CD1 . LEU C 1 107 ? 151.974 143.854 144.862 1.00 85.58  ? 181 LEU C CD1 1 
ATOM 5153 C CD2 . LEU C 1 107 ? 151.263 144.236 142.495 1.00 88.19  ? 181 LEU C CD2 1 
ATOM 5154 N N   . GLY C 1 108 ? 147.716 140.794 142.384 1.00 97.33  ? 182 GLY C N   1 
ATOM 5155 C CA  . GLY C 1 108 ? 146.881 139.610 142.430 1.00 96.12  ? 182 GLY C CA  1 
ATOM 5156 C C   . GLY C 1 108 ? 146.023 139.482 141.187 1.00 97.04  ? 182 GLY C C   1 
ATOM 5157 O O   . GLY C 1 108 ? 145.907 140.396 140.373 1.00 97.37  ? 182 GLY C O   1 
ATOM 5158 N N   . GLY C 1 109 ? 145.412 138.306 141.060 1.00 101.05 ? 183 GLY C N   1 
ATOM 5159 C CA  . GLY C 1 109 ? 144.627 137.996 139.880 1.00 102.33 ? 183 GLY C CA  1 
ATOM 5160 C C   . GLY C 1 109 ? 143.140 137.826 140.117 1.00 103.62 ? 183 GLY C C   1 
ATOM 5161 O O   . GLY C 1 109 ? 142.713 136.854 140.748 1.00 104.39 ? 183 GLY C O   1 
ATOM 5162 N N   . ASP C 1 110 ? 142.345 138.780 139.625 1.00 98.58  ? 184 ASP C N   1 
ATOM 5163 C CA  . ASP C 1 110 ? 140.886 138.696 139.605 1.00 96.60  ? 184 ASP C CA  1 
ATOM 5164 C C   . ASP C 1 110 ? 140.268 138.620 140.997 1.00 96.26  ? 184 ASP C C   1 
ATOM 5165 O O   . ASP C 1 110 ? 139.050 138.463 141.127 1.00 98.92  ? 184 ASP C O   1 
ATOM 5166 C CB  . ASP C 1 110 ? 140.429 137.492 138.775 1.00 96.77  ? 184 ASP C CB  1 
ATOM 5167 C CG  . ASP C 1 110 ? 140.789 137.622 137.310 1.00 97.33  ? 184 ASP C CG  1 
ATOM 5168 O OD1 . ASP C 1 110 ? 140.908 138.767 136.824 1.00 94.83  ? 184 ASP C OD1 1 
ATOM 5169 O OD2 . ASP C 1 110 ? 140.944 136.578 136.643 1.00 98.70  ? 184 ASP C OD2 1 
ATOM 5170 N N   . GLY C 1 111 ? 141.086 138.729 142.039 1.00 76.33  ? 185 GLY C N   1 
ATOM 5171 C CA  . GLY C 1 111 ? 140.576 138.670 143.393 1.00 70.79  ? 185 GLY C CA  1 
ATOM 5172 C C   . GLY C 1 111 ? 140.860 139.938 144.166 1.00 70.26  ? 185 GLY C C   1 
ATOM 5173 O O   . GLY C 1 111 ? 140.217 140.217 145.182 1.00 70.47  ? 185 GLY C O   1 
ATOM 5174 N N   . THR C 1 112 ? 141.827 140.717 143.687 1.00 70.06  ? 186 THR C N   1 
ATOM 5175 C CA  . THR C 1 112 ? 142.224 141.947 144.355 1.00 71.37  ? 186 THR C CA  1 
ATOM 5176 C C   . THR C 1 112 ? 141.376 143.137 143.924 1.00 70.84  ? 186 THR C C   1 
ATOM 5177 O O   . THR C 1 112 ? 141.009 143.969 144.760 1.00 70.88  ? 186 THR C O   1 
ATOM 5178 C CB  . THR C 1 112 ? 143.704 142.234 144.087 1.00 70.46  ? 186 THR C CB  1 
ATOM 5179 O OG1 . THR C 1 112 ? 144.495 141.140 144.566 1.00 72.77  ? 186 THR C OG1 1 
ATOM 5180 C CG2 . THR C 1 112 ? 144.139 143.500 144.803 1.00 70.60  ? 186 THR C CG2 1 
ATOM 5181 N N   . LEU C 1 113 ? 141.050 143.231 142.632 1.00 72.52  ? 187 LEU C N   1 
ATOM 5182 C CA  . LEU C 1 113 ? 140.232 144.344 142.161 1.00 71.69  ? 187 LEU C CA  1 
ATOM 5183 C C   . LEU C 1 113 ? 138.831 144.300 142.757 1.00 73.95  ? 187 LEU C C   1 
ATOM 5184 O O   . LEU C 1 113 ? 138.221 145.353 142.979 1.00 74.54  ? 187 LEU C O   1 
ATOM 5185 C CB  . LEU C 1 113 ? 140.166 144.341 140.634 1.00 61.84  ? 187 LEU C CB  1 
ATOM 5186 C CG  . LEU C 1 113 ? 139.412 145.505 139.986 1.00 64.73  ? 187 LEU C CG  1 
ATOM 5187 C CD1 . LEU C 1 113 ? 139.864 146.832 140.573 1.00 66.83  ? 187 LEU C CD1 1 
ATOM 5188 C CD2 . LEU C 1 113 ? 139.590 145.500 138.478 1.00 71.43  ? 187 LEU C CD2 1 
ATOM 5189 N N   . LEU C 1 114 ? 138.305 143.102 143.022 1.00 69.16  ? 188 LEU C N   1 
ATOM 5190 C CA  . LEU C 1 114 ? 137.025 142.999 143.714 1.00 64.55  ? 188 LEU C CA  1 
ATOM 5191 C C   . LEU C 1 114 ? 137.111 143.593 145.112 1.00 63.44  ? 188 LEU C C   1 
ATOM 5192 O O   . LEU C 1 114 ? 136.200 144.305 145.550 1.00 64.55  ? 188 LEU C O   1 
ATOM 5193 C CB  . LEU C 1 114 ? 136.578 141.540 143.779 1.00 65.53  ? 188 LEU C CB  1 
ATOM 5194 C CG  . LEU C 1 114 ? 136.092 140.936 142.465 1.00 64.79  ? 188 LEU C CG  1 
ATOM 5195 C CD1 . LEU C 1 114 ? 135.638 139.502 142.672 1.00 62.33  ? 188 LEU C CD1 1 
ATOM 5196 C CD2 . LEU C 1 114 ? 134.967 141.784 141.898 1.00 65.93  ? 188 LEU C CD2 1 
ATOM 5197 N N   . TYR C 1 115 ? 138.199 143.309 145.830 1.00 52.15  ? 189 TYR C N   1 
ATOM 5198 C CA  . TYR C 1 115 ? 138.389 143.905 147.146 1.00 52.71  ? 189 TYR C CA  1 
ATOM 5199 C C   . TYR C 1 115 ? 138.606 145.407 147.051 1.00 58.64  ? 189 TYR C C   1 
ATOM 5200 O O   . TYR C 1 115 ? 138.208 146.148 147.957 1.00 63.92  ? 189 TYR C O   1 
ATOM 5201 C CB  . TYR C 1 115 ? 139.564 143.240 147.859 1.00 54.15  ? 189 TYR C CB  1 
ATOM 5202 C CG  . TYR C 1 115 ? 139.889 143.846 149.203 1.00 53.11  ? 189 TYR C CG  1 
ATOM 5203 C CD1 . TYR C 1 115 ? 139.148 143.522 150.328 1.00 56.54  ? 189 TYR C CD1 1 
ATOM 5204 C CD2 . TYR C 1 115 ? 140.941 144.736 149.347 1.00 51.17  ? 189 TYR C CD2 1 
ATOM 5205 C CE1 . TYR C 1 115 ? 139.444 144.072 151.558 1.00 59.71  ? 189 TYR C CE1 1 
ATOM 5206 C CE2 . TYR C 1 115 ? 141.244 145.289 150.569 1.00 51.86  ? 189 TYR C CE2 1 
ATOM 5207 C CZ  . TYR C 1 115 ? 140.494 144.955 151.671 1.00 59.38  ? 189 TYR C CZ  1 
ATOM 5208 O OH  . TYR C 1 115 ? 140.795 145.508 152.895 1.00 62.99  ? 189 TYR C OH  1 
ATOM 5209 N N   . ALA C 1 116 ? 139.239 145.875 145.972 1.00 56.69  ? 190 ALA C N   1 
ATOM 5210 C CA  . ALA C 1 116 ? 139.445 147.309 145.803 1.00 57.64  ? 190 ALA C CA  1 
ATOM 5211 C C   . ALA C 1 116 ? 138.118 148.044 145.670 1.00 56.94  ? 190 ALA C C   1 
ATOM 5212 O O   . ALA C 1 116 ? 137.941 149.128 146.237 1.00 58.21  ? 190 ALA C O   1 
ATOM 5213 C CB  . ALA C 1 116 ? 140.331 147.573 144.587 1.00 58.85  ? 190 ALA C CB  1 
ATOM 5214 N N   . SER C 1 117 ? 137.172 147.470 144.923 1.00 61.85  ? 191 SER C N   1 
ATOM 5215 C CA  . SER C 1 117 ? 135.860 148.095 144.790 1.00 61.53  ? 191 SER C CA  1 
ATOM 5216 C C   . SER C 1 117 ? 135.090 148.067 146.101 1.00 64.17  ? 191 SER C C   1 
ATOM 5217 O O   . SER C 1 117 ? 134.251 148.942 146.343 1.00 67.26  ? 191 SER C O   1 
ATOM 5218 C CB  . SER C 1 117 ? 135.052 147.404 143.694 1.00 56.08  ? 191 SER C CB  1 
ATOM 5219 O OG  . SER C 1 117 ? 134.852 146.037 143.999 1.00 59.79  ? 191 SER C OG  1 
ATOM 5220 N N   . SER C 1 118 ? 135.351 147.072 146.951 1.00 62.64  ? 192 SER C N   1 
ATOM 5221 C CA  . SER C 1 118 ? 134.629 146.972 148.215 1.00 61.80  ? 192 SER C CA  1 
ATOM 5222 C C   . SER C 1 118 ? 134.918 148.166 149.113 1.00 61.16  ? 192 SER C C   1 
ATOM 5223 O O   . SER C 1 118 ? 134.009 148.702 149.757 1.00 66.56  ? 192 SER C O   1 
ATOM 5224 C CB  . SER C 1 118 ? 134.992 145.671 148.927 1.00 64.93  ? 192 SER C CB  1 
ATOM 5225 O OG  . SER C 1 118 ? 136.374 145.628 149.232 1.00 67.12  ? 192 SER C OG  1 
ATOM 5226 N N   . LEU C 1 119 ? 136.179 148.599 149.171 1.00 57.00  ? 193 LEU C N   1 
ATOM 5227 C CA  . LEU C 1 119 ? 136.532 149.706 150.050 1.00 62.48  ? 193 LEU C CA  1 
ATOM 5228 C C   . LEU C 1 119 ? 136.077 151.052 149.506 1.00 61.03  ? 193 LEU C C   1 
ATOM 5229 O O   . LEU C 1 119 ? 136.089 152.040 150.247 1.00 61.65  ? 193 LEU C O   1 
ATOM 5230 C CB  . LEU C 1 119 ? 138.041 149.731 150.292 1.00 58.01  ? 193 LEU C CB  1 
ATOM 5231 C CG  . LEU C 1 119 ? 138.652 148.457 150.870 1.00 58.49  ? 193 LEU C CG  1 
ATOM 5232 C CD1 . LEU C 1 119 ? 140.145 148.635 151.072 1.00 61.56  ? 193 LEU C CD1 1 
ATOM 5233 C CD2 . LEU C 1 119 ? 137.972 148.085 152.176 1.00 61.04  ? 193 LEU C CD2 1 
ATOM 5234 N N   . PHE C 1 120 ? 135.674 151.117 148.240 1.00 55.24  ? 194 PHE C N   1 
ATOM 5235 C CA  . PHE C 1 120 ? 135.278 152.369 147.603 1.00 60.63  ? 194 PHE C CA  1 
ATOM 5236 C C   . PHE C 1 120 ? 133.857 152.218 147.070 1.00 64.79  ? 194 PHE C C   1 
ATOM 5237 O O   . PHE C 1 120 ? 133.649 151.782 145.935 1.00 58.56  ? 194 PHE C O   1 
ATOM 5238 C CB  . PHE C 1 120 ? 136.252 152.748 146.495 1.00 60.87  ? 194 PHE C CB  1 
ATOM 5239 C CG  . PHE C 1 120 ? 137.621 153.105 146.991 1.00 60.43  ? 194 PHE C CG  1 
ATOM 5240 C CD1 . PHE C 1 120 ? 138.543 152.117 147.287 1.00 62.22  ? 194 PHE C CD1 1 
ATOM 5241 C CD2 . PHE C 1 120 ? 137.986 154.426 147.162 1.00 58.09  ? 194 PHE C CD2 1 
ATOM 5242 C CE1 . PHE C 1 120 ? 139.801 152.442 147.744 1.00 58.00  ? 194 PHE C CE1 1 
ATOM 5243 C CE2 . PHE C 1 120 ? 139.243 154.756 147.618 1.00 61.53  ? 194 PHE C CE2 1 
ATOM 5244 C CZ  . PHE C 1 120 ? 140.152 153.762 147.909 1.00 59.89  ? 194 PHE C CZ  1 
ATOM 5245 N N   . GLN C 1 121 ? 132.879 152.581 147.898 1.00 66.51  ? 195 GLN C N   1 
ATOM 5246 C CA  . GLN C 1 121 ? 131.489 152.600 147.469 1.00 64.14  ? 195 GLN C CA  1 
ATOM 5247 C C   . GLN C 1 121 ? 131.133 153.857 146.688 1.00 61.29  ? 195 GLN C C   1 
ATOM 5248 O O   . GLN C 1 121 ? 130.087 153.883 146.031 1.00 66.35  ? 195 GLN C O   1 
ATOM 5249 C CB  . GLN C 1 121 ? 130.562 152.469 148.679 1.00 64.78  ? 195 GLN C CB  1 
ATOM 5250 C CG  . GLN C 1 121 ? 130.748 151.186 149.470 1.00 64.65  ? 195 GLN C CG  1 
ATOM 5251 C CD  . GLN C 1 121 ? 130.368 149.952 148.678 1.00 65.26  ? 195 GLN C CD  1 
ATOM 5252 O OE1 . GLN C 1 121 ? 129.204 149.555 148.649 1.00 64.74  ? 195 GLN C OE1 1 
ATOM 5253 N NE2 . GLN C 1 121 ? 131.352 149.334 148.036 1.00 62.44  ? 195 GLN C NE2 1 
ATOM 5254 N N   . GLY C 1 122 ? 131.970 154.889 146.741 1.00 50.70  ? 196 GLY C N   1 
ATOM 5255 C CA  . GLY C 1 122 ? 131.727 156.103 145.990 1.00 54.76  ? 196 GLY C CA  1 
ATOM 5256 C C   . GLY C 1 122 ? 132.532 156.155 144.710 1.00 64.20  ? 196 GLY C C   1 
ATOM 5257 O O   . GLY C 1 122 ? 132.584 155.171 143.965 1.00 68.68  ? 196 GLY C O   1 
ATOM 5258 N N   . SER C 1 123 ? 133.173 157.290 144.444 1.00 66.36  ? 197 SER C N   1 
ATOM 5259 C CA  . SER C 1 123 ? 133.977 157.454 143.238 1.00 61.88  ? 197 SER C CA  1 
ATOM 5260 C C   . SER C 1 123 ? 135.336 156.803 143.458 1.00 65.93  ? 197 SER C C   1 
ATOM 5261 O O   . SER C 1 123 ? 136.208 157.376 144.118 1.00 72.89  ? 197 SER C O   1 
ATOM 5262 C CB  . SER C 1 123 ? 134.124 158.932 142.890 1.00 63.17  ? 197 SER C CB  1 
ATOM 5263 O OG  . SER C 1 123 ? 134.751 159.643 143.943 1.00 71.10  ? 197 SER C OG  1 
ATOM 5264 N N   . VAL C 1 124 ? 135.518 155.610 142.910 1.00 54.78  ? 198 VAL C N   1 
ATOM 5265 C CA  . VAL C 1 124 ? 136.782 154.887 143.068 1.00 59.50  ? 198 VAL C CA  1 
ATOM 5266 C C   . VAL C 1 124 ? 137.819 155.490 142.122 1.00 60.89  ? 198 VAL C C   1 
ATOM 5267 O O   . VAL C 1 124 ? 137.491 155.790 140.962 1.00 62.41  ? 198 VAL C O   1 
ATOM 5268 C CB  . VAL C 1 124 ? 136.584 153.392 142.811 1.00 48.80  ? 198 VAL C CB  1 
ATOM 5269 C CG1 . VAL C 1 124 ? 136.130 153.132 141.391 1.00 51.50  ? 198 VAL C CG1 1 
ATOM 5270 C CG2 . VAL C 1 124 ? 137.858 152.620 143.109 1.00 51.99  ? 198 VAL C CG2 1 
ATOM 5271 N N   . PRO C 1 125 ? 139.044 155.727 142.580 1.00 58.73  ? 199 PRO C N   1 
ATOM 5272 C CA  . PRO C 1 125 ? 140.077 156.286 141.701 1.00 55.54  ? 199 PRO C CA  1 
ATOM 5273 C C   . PRO C 1 125 ? 140.536 155.259 140.682 1.00 57.38  ? 199 PRO C C   1 
ATOM 5274 O O   . PRO C 1 125 ? 140.178 154.076 140.783 1.00 64.97  ? 199 PRO C O   1 
ATOM 5275 C CB  . PRO C 1 125 ? 141.207 156.654 142.677 1.00 63.49  ? 199 PRO C CB  1 
ATOM 5276 C CG  . PRO C 1 125 ? 140.980 155.791 143.864 1.00 61.73  ? 199 PRO C CG  1 
ATOM 5277 C CD  . PRO C 1 125 ? 139.498 155.631 143.978 1.00 59.34  ? 199 PRO C CD  1 
ATOM 5278 N N   . PRO C 1 126 ? 141.312 155.669 139.676 1.00 51.18  ? 200 PRO C N   1 
ATOM 5279 C CA  . PRO C 1 126 ? 141.816 154.699 138.696 1.00 55.94  ? 200 PRO C CA  1 
ATOM 5280 C C   . PRO C 1 126 ? 142.646 153.612 139.360 1.00 59.00  ? 200 PRO C C   1 
ATOM 5281 O O   . PRO C 1 126 ? 143.403 153.865 140.299 1.00 65.51  ? 200 PRO C O   1 
ATOM 5282 C CB  . PRO C 1 126 ? 142.662 155.555 137.746 1.00 60.85  ? 200 PRO C CB  1 
ATOM 5283 C CG  . PRO C 1 126 ? 142.901 156.838 138.474 1.00 60.75  ? 200 PRO C CG  1 
ATOM 5284 C CD  . PRO C 1 126 ? 141.689 157.045 139.317 1.00 56.71  ? 200 PRO C CD  1 
ATOM 5285 N N   . VAL C 1 127 ? 142.492 152.389 138.861 1.00 59.90  ? 201 VAL C N   1 
ATOM 5286 C CA  . VAL C 1 127 ? 143.128 151.209 139.432 1.00 58.44  ? 201 VAL C CA  1 
ATOM 5287 C C   . VAL C 1 127 ? 144.003 150.566 138.368 1.00 56.94  ? 201 VAL C C   1 
ATOM 5288 O O   . VAL C 1 127 ? 143.542 150.309 137.250 1.00 70.40  ? 201 VAL C O   1 
ATOM 5289 C CB  . VAL C 1 127 ? 142.090 150.202 139.956 1.00 67.37  ? 201 VAL C CB  1 
ATOM 5290 C CG1 . VAL C 1 127 ? 142.786 148.988 140.542 1.00 68.15  ? 201 VAL C CG1 1 
ATOM 5291 C CG2 . VAL C 1 127 ? 141.187 150.856 140.989 1.00 68.34  ? 201 VAL C CG2 1 
ATOM 5292 N N   . MET C 1 128 ? 145.257 150.307 138.716 1.00 55.97  ? 202 MET C N   1 
ATOM 5293 C CA  . MET C 1 128 ? 146.191 149.603 137.850 1.00 64.66  ? 202 MET C CA  1 
ATOM 5294 C C   . MET C 1 128 ? 146.534 148.275 138.507 1.00 62.64  ? 202 MET C C   1 
ATOM 5295 O O   . MET C 1 128 ? 147.094 148.251 139.608 1.00 74.16  ? 202 MET C O   1 
ATOM 5296 C CB  . MET C 1 128 ? 147.449 150.437 137.608 1.00 72.39  ? 202 MET C CB  1 
ATOM 5297 C CG  . MET C 1 128 ? 148.524 149.726 136.807 1.00 76.87  ? 202 MET C CG  1 
ATOM 5298 S SD  . MET C 1 128 ? 149.932 150.786 136.427 1.00 89.48  ? 202 MET C SD  1 
ATOM 5299 C CE  . MET C 1 128 ? 150.434 151.290 138.069 1.00 70.33  ? 202 MET C CE  1 
ATOM 5300 N N   . ALA C 1 129 ? 146.205 147.178 137.834 1.00 45.89  ? 203 ALA C N   1 
ATOM 5301 C CA  . ALA C 1 129 ? 146.333 145.844 138.400 1.00 52.13  ? 203 ALA C CA  1 
ATOM 5302 C C   . ALA C 1 129 ? 147.477 145.104 137.726 1.00 59.45  ? 203 ALA C C   1 
ATOM 5303 O O   . ALA C 1 129 ? 147.570 145.082 136.495 1.00 64.21  ? 203 ALA C O   1 
ATOM 5304 C CB  . ALA C 1 129 ? 145.031 145.058 138.249 1.00 59.87  ? 203 ALA C CB  1 
ATOM 5305 N N   . PHE C 1 130 ? 148.341 144.501 138.537 1.00 63.85  ? 204 PHE C N   1 
ATOM 5306 C CA  . PHE C 1 130 ? 149.478 143.728 138.064 1.00 63.08  ? 204 PHE C CA  1 
ATOM 5307 C C   . PHE C 1 130 ? 149.221 142.245 138.285 1.00 66.56  ? 204 PHE C C   1 
ATOM 5308 O O   . PHE C 1 130 ? 148.658 141.851 139.310 1.00 68.03  ? 204 PHE C O   1 
ATOM 5309 C CB  . PHE C 1 130 ? 150.763 144.140 138.786 1.00 65.04  ? 204 PHE C CB  1 
ATOM 5310 C CG  . PHE C 1 130 ? 151.206 145.542 138.491 1.00 63.99  ? 204 PHE C CG  1 
ATOM 5311 C CD1 . PHE C 1 130 ? 150.683 146.613 139.190 1.00 66.78  ? 204 PHE C CD1 1 
ATOM 5312 C CD2 . PHE C 1 130 ? 152.161 145.785 137.522 1.00 67.49  ? 204 PHE C CD2 1 
ATOM 5313 C CE1 . PHE C 1 130 ? 151.098 147.900 138.918 1.00 67.50  ? 204 PHE C CE1 1 
ATOM 5314 C CE2 . PHE C 1 130 ? 152.577 147.068 137.247 1.00 66.63  ? 204 PHE C CE2 1 
ATOM 5315 C CZ  . PHE C 1 130 ? 152.047 148.127 137.944 1.00 64.80  ? 204 PHE C CZ  1 
ATOM 5316 N N   . HIS C 1 131 ? 149.632 141.424 137.320 1.00 86.63  ? 205 HIS C N   1 
ATOM 5317 C CA  . HIS C 1 131 ? 149.504 139.974 137.420 1.00 88.60  ? 205 HIS C CA  1 
ATOM 5318 C C   . HIS C 1 131 ? 150.895 139.375 137.587 1.00 88.81  ? 205 HIS C C   1 
ATOM 5319 O O   . HIS C 1 131 ? 151.791 139.626 136.773 1.00 86.52  ? 205 HIS C O   1 
ATOM 5320 C CB  . HIS C 1 131 ? 148.803 139.389 136.196 1.00 87.62  ? 205 HIS C CB  1 
ATOM 5321 C CG  . HIS C 1 131 ? 149.533 139.615 134.910 1.00 87.80  ? 205 HIS C CG  1 
ATOM 5322 N ND1 . HIS C 1 131 ? 149.554 140.835 134.269 1.00 91.23  ? 205 HIS C ND1 1 
ATOM 5323 C CD2 . HIS C 1 131 ? 150.271 138.776 134.147 1.00 89.67  ? 205 HIS C CD2 1 
ATOM 5324 C CE1 . HIS C 1 131 ? 150.270 140.735 133.163 1.00 90.61  ? 205 HIS C CE1 1 
ATOM 5325 N NE2 . HIS C 1 131 ? 150.719 139.497 133.067 1.00 89.96  ? 205 HIS C NE2 1 
ATOM 5326 N N   . LEU C 1 132 ? 151.076 138.592 138.645 1.00 103.11 ? 206 LEU C N   1 
ATOM 5327 C CA  . LEU C 1 132 ? 152.338 137.911 138.918 1.00 102.74 ? 206 LEU C CA  1 
ATOM 5328 C C   . LEU C 1 132 ? 152.070 136.411 138.877 1.00 104.45 ? 206 LEU C C   1 
ATOM 5329 O O   . LEU C 1 132 ? 151.651 135.815 139.872 1.00 104.01 ? 206 LEU C O   1 
ATOM 5330 C CB  . LEU C 1 132 ? 152.914 138.352 140.259 1.00 102.22 ? 206 LEU C CB  1 
ATOM 5331 C CG  . LEU C 1 132 ? 153.180 139.854 140.391 1.00 100.75 ? 206 LEU C CG  1 
ATOM 5332 C CD1 . LEU C 1 132 ? 152.014 140.566 141.066 1.00 100.49 ? 206 LEU C CD1 1 
ATOM 5333 C CD2 . LEU C 1 132 ? 154.475 140.108 141.137 1.00 100.19 ? 206 LEU C CD2 1 
ATOM 5334 N N   . GLY C 1 133 ? 152.314 135.803 137.719 1.00 110.90 ? 207 GLY C N   1 
ATOM 5335 C CA  . GLY C 1 133 ? 151.991 134.406 137.516 1.00 110.39 ? 207 GLY C CA  1 
ATOM 5336 C C   . GLY C 1 133 ? 150.773 134.230 136.633 1.00 111.78 ? 207 GLY C C   1 
ATOM 5337 O O   . GLY C 1 133 ? 150.854 134.396 135.413 1.00 111.04 ? 207 GLY C O   1 
ATOM 5338 N N   . SER C 1 134 ? 149.640 133.888 137.239 1.00 110.54 ? 208 SER C N   1 
ATOM 5339 C CA  . SER C 1 134 ? 148.398 133.775 136.490 1.00 109.40 ? 208 SER C CA  1 
ATOM 5340 C C   . SER C 1 134 ? 147.928 135.148 136.021 1.00 107.97 ? 208 SER C C   1 
ATOM 5341 O O   . SER C 1 134 ? 148.054 136.150 136.730 1.00 108.28 ? 208 SER C O   1 
ATOM 5342 C CB  . SER C 1 134 ? 147.316 133.116 137.345 1.00 108.64 ? 208 SER C CB  1 
ATOM 5343 O OG  . SER C 1 134 ? 147.072 133.864 138.524 1.00 109.13 ? 208 SER C OG  1 
ATOM 5344 N N   . LEU C 1 135 ? 147.382 135.186 134.809 1.00 98.62  ? 209 LEU C N   1 
ATOM 5345 C CA  . LEU C 1 135 ? 146.884 136.414 134.205 1.00 99.84  ? 209 LEU C CA  1 
ATOM 5346 C C   . LEU C 1 135 ? 145.364 136.372 134.181 1.00 100.74 ? 209 LEU C C   1 
ATOM 5347 O O   . LEU C 1 135 ? 144.772 135.381 133.742 1.00 100.29 ? 209 LEU C O   1 
ATOM 5348 C CB  . LEU C 1 135 ? 147.446 136.594 132.791 1.00 101.36 ? 209 LEU C CB  1 
ATOM 5349 C CG  . LEU C 1 135 ? 147.200 137.916 132.054 1.00 101.44 ? 209 LEU C CG  1 
ATOM 5350 C CD1 . LEU C 1 135 ? 148.344 138.196 131.096 1.00 100.12 ? 209 LEU C CD1 1 
ATOM 5351 C CD2 . LEU C 1 135 ? 145.881 137.901 131.293 1.00 99.60  ? 209 LEU C CD2 1 
ATOM 5352 N N   . GLY C 1 136 ? 144.736 137.449 134.652 1.00 92.56  ? 210 GLY C N   1 
ATOM 5353 C CA  . GLY C 1 136 ? 143.299 137.541 134.731 1.00 90.69  ? 210 GLY C CA  1 
ATOM 5354 C C   . GLY C 1 136 ? 142.718 138.575 133.780 1.00 92.07  ? 210 GLY C C   1 
ATOM 5355 O O   . GLY C 1 136 ? 143.416 139.240 133.018 1.00 93.47  ? 210 GLY C O   1 
ATOM 5356 N N   . PHE C 1 137 ? 141.393 138.695 133.846 1.00 86.18  ? 211 PHE C N   1 
ATOM 5357 C CA  . PHE C 1 137 ? 140.677 139.647 133.008 1.00 83.87  ? 211 PHE C CA  1 
ATOM 5358 C C   . PHE C 1 137 ? 140.760 141.069 133.539 1.00 84.24  ? 211 PHE C C   1 
ATOM 5359 O O   . PHE C 1 137 ? 140.420 142.009 132.813 1.00 86.11  ? 211 PHE C O   1 
ATOM 5360 C CB  . PHE C 1 137 ? 139.211 139.232 132.881 1.00 82.38  ? 211 PHE C CB  1 
ATOM 5361 C CG  . PHE C 1 137 ? 139.001 138.018 132.029 1.00 82.75  ? 211 PHE C CG  1 
ATOM 5362 C CD1 . PHE C 1 137 ? 138.881 138.131 130.657 1.00 84.54  ? 211 PHE C CD1 1 
ATOM 5363 C CD2 . PHE C 1 137 ? 138.929 136.760 132.602 1.00 83.41  ? 211 PHE C CD2 1 
ATOM 5364 C CE1 . PHE C 1 137 ? 138.691 137.013 129.872 1.00 86.63  ? 211 PHE C CE1 1 
ATOM 5365 C CE2 . PHE C 1 137 ? 138.738 135.638 131.822 1.00 84.25  ? 211 PHE C CE2 1 
ATOM 5366 C CZ  . PHE C 1 137 ? 138.618 135.765 130.455 1.00 85.17  ? 211 PHE C CZ  1 
ATOM 5367 N N   . LEU C 1 138 ? 141.200 141.245 134.782 1.00 79.41  ? 212 LEU C N   1 
ATOM 5368 C CA  . LEU C 1 138 ? 141.272 142.553 135.414 1.00 80.77  ? 212 LEU C CA  1 
ATOM 5369 C C   . LEU C 1 138 ? 142.695 143.080 135.529 1.00 86.83  ? 212 LEU C C   1 
ATOM 5370 O O   . LEU C 1 138 ? 142.883 144.225 135.954 1.00 87.66  ? 212 LEU C O   1 
ATOM 5371 C CB  . LEU C 1 138 ? 140.640 142.490 136.809 1.00 82.03  ? 212 LEU C CB  1 
ATOM 5372 C CG  . LEU C 1 138 ? 139.293 141.773 136.926 1.00 82.38  ? 212 LEU C CG  1 
ATOM 5373 C CD1 . LEU C 1 138 ? 138.817 141.754 138.371 1.00 83.75  ? 212 LEU C CD1 1 
ATOM 5374 C CD2 . LEU C 1 138 ? 138.253 142.409 136.026 1.00 83.03  ? 212 LEU C CD2 1 
ATOM 5375 N N   . THR C 1 139 ? 143.699 142.285 135.157 1.00 87.71  ? 213 THR C N   1 
ATOM 5376 C CA  . THR C 1 139 ? 145.105 142.591 135.423 1.00 82.55  ? 213 THR C CA  1 
ATOM 5377 C C   . THR C 1 139 ? 145.883 142.584 134.115 1.00 76.34  ? 213 THR C C   1 
ATOM 5378 O O   . THR C 1 139 ? 146.431 141.551 133.707 1.00 79.24  ? 213 THR C O   1 
ATOM 5379 C CB  . THR C 1 139 ? 145.704 141.588 136.408 1.00 84.77  ? 213 THR C CB  1 
ATOM 5380 O OG1 . THR C 1 139 ? 145.767 140.297 135.791 1.00 86.97  ? 213 THR C OG1 1 
ATOM 5381 C CG2 . THR C 1 139 ? 144.842 141.492 137.651 1.00 81.50  ? 213 THR C CG2 1 
ATOM 5382 N N   . PRO C 1 140 ? 145.950 143.718 133.429 1.00 74.34  ? 214 PRO C N   1 
ATOM 5383 C CA  . PRO C 1 140 ? 146.674 143.765 132.153 1.00 82.56  ? 214 PRO C CA  1 
ATOM 5384 C C   . PRO C 1 140 ? 148.179 143.940 132.296 1.00 85.95  ? 214 PRO C C   1 
ATOM 5385 O O   . PRO C 1 140 ? 148.943 143.448 131.459 1.00 86.65  ? 214 PRO C O   1 
ATOM 5386 C CB  . PRO C 1 140 ? 146.046 144.974 131.452 1.00 82.93  ? 214 PRO C CB  1 
ATOM 5387 C CG  . PRO C 1 140 ? 145.647 145.868 132.571 1.00 83.53  ? 214 PRO C CG  1 
ATOM 5388 C CD  . PRO C 1 140 ? 145.220 144.968 133.699 1.00 78.23  ? 214 PRO C CD  1 
ATOM 5389 N N   . PHE C 1 141 ? 148.619 144.630 133.344 1.00 79.91  ? 215 PHE C N   1 
ATOM 5390 C CA  . PHE C 1 141 ? 150.012 145.045 133.446 1.00 75.57  ? 215 PHE C CA  1 
ATOM 5391 C C   . PHE C 1 141 ? 150.909 143.905 133.907 1.00 75.19  ? 215 PHE C C   1 
ATOM 5392 O O   . PHE C 1 141 ? 150.592 143.186 134.858 1.00 78.63  ? 215 PHE C O   1 
ATOM 5393 C CB  . PHE C 1 141 ? 150.144 146.225 134.406 1.00 74.64  ? 215 PHE C CB  1 
ATOM 5394 C CG  . PHE C 1 141 ? 149.689 147.529 133.825 1.00 71.95  ? 215 PHE C CG  1 
ATOM 5395 C CD1 . PHE C 1 141 ? 148.354 147.878 133.836 1.00 71.75  ? 215 PHE C CD1 1 
ATOM 5396 C CD2 . PHE C 1 141 ? 150.602 148.408 133.275 1.00 77.57  ? 215 PHE C CD2 1 
ATOM 5397 C CE1 . PHE C 1 141 ? 147.935 149.078 133.306 1.00 75.38  ? 215 PHE C CE1 1 
ATOM 5398 C CE2 . PHE C 1 141 ? 150.190 149.609 132.743 1.00 79.01  ? 215 PHE C CE2 1 
ATOM 5399 C CZ  . PHE C 1 141 ? 148.855 149.945 132.758 1.00 80.18  ? 215 PHE C CZ  1 
ATOM 5400 N N   . SER C 1 142 ? 152.043 143.756 133.228 1.00 77.85  ? 216 SER C N   1 
ATOM 5401 C CA  . SER C 1 142 ? 153.055 142.780 133.602 1.00 82.19  ? 216 SER C CA  1 
ATOM 5402 C C   . SER C 1 142 ? 154.040 143.411 134.576 1.00 85.15  ? 216 SER C C   1 
ATOM 5403 O O   . SER C 1 142 ? 154.342 144.604 134.486 1.00 85.95  ? 216 SER C O   1 
ATOM 5404 C CB  . SER C 1 142 ? 153.794 142.264 132.367 1.00 85.83  ? 216 SER C CB  1 
ATOM 5405 O OG  . SER C 1 142 ? 154.721 141.250 132.713 1.00 88.64  ? 216 SER C OG  1 
ATOM 5406 N N   . PHE C 1 143 ? 154.540 142.602 135.512 1.00 95.72  ? 217 PHE C N   1 
ATOM 5407 C CA  . PHE C 1 143 ? 155.385 143.138 136.571 1.00 95.17  ? 217 PHE C CA  1 
ATOM 5408 C C   . PHE C 1 143 ? 156.790 143.479 136.091 1.00 97.51  ? 217 PHE C C   1 
ATOM 5409 O O   . PHE C 1 143 ? 157.485 144.251 136.760 1.00 98.96  ? 217 PHE C O   1 
ATOM 5410 C CB  . PHE C 1 143 ? 155.460 142.156 137.739 1.00 96.46  ? 217 PHE C CB  1 
ATOM 5411 C CG  . PHE C 1 143 ? 156.032 142.754 138.991 1.00 98.09  ? 217 PHE C CG  1 
ATOM 5412 C CD1 . PHE C 1 143 ? 155.263 143.584 139.788 1.00 95.78  ? 217 PHE C CD1 1 
ATOM 5413 C CD2 . PHE C 1 143 ? 157.338 142.491 139.369 1.00 97.76  ? 217 PHE C CD2 1 
ATOM 5414 C CE1 . PHE C 1 143 ? 155.784 144.140 140.939 1.00 96.15  ? 217 PHE C CE1 1 
ATOM 5415 C CE2 . PHE C 1 143 ? 157.865 143.045 140.520 1.00 96.83  ? 217 PHE C CE2 1 
ATOM 5416 C CZ  . PHE C 1 143 ? 157.086 143.871 141.305 1.00 96.71  ? 217 PHE C CZ  1 
ATOM 5417 N N   . GLU C 1 144 ? 157.225 142.929 134.961 1.00 103.17 ? 218 GLU C N   1 
ATOM 5418 C CA  . GLU C 1 144 ? 158.548 143.248 134.445 1.00 102.48 ? 218 GLU C CA  1 
ATOM 5419 C C   . GLU C 1 144 ? 158.620 144.714 134.036 1.00 102.11 ? 218 GLU C C   1 
ATOM 5420 O O   . GLU C 1 144 ? 157.679 145.259 133.452 1.00 102.48 ? 218 GLU C O   1 
ATOM 5421 C CB  . GLU C 1 144 ? 158.893 142.341 133.263 1.00 102.52 ? 218 GLU C CB  1 
ATOM 5422 C CG  . GLU C 1 144 ? 157.852 142.312 132.152 1.00 103.80 ? 218 GLU C CG  1 
ATOM 5423 C CD  . GLU C 1 144 ? 158.082 143.382 131.101 1.00 104.46 ? 218 GLU C CD  1 
ATOM 5424 O OE1 . GLU C 1 144 ? 159.198 143.941 131.054 1.00 104.52 ? 218 GLU C OE1 1 
ATOM 5425 O OE2 . GLU C 1 144 ? 157.147 143.664 130.323 1.00 101.73 ? 218 GLU C OE2 1 
ATOM 5426 N N   . ASN C 1 145 ? 159.747 145.352 134.355 1.00 95.78  ? 219 ASN C N   1 
ATOM 5427 C CA  . ASN C 1 145 ? 159.954 146.778 134.102 1.00 95.88  ? 219 ASN C CA  1 
ATOM 5428 C C   . ASN C 1 145 ? 158.819 147.609 134.696 1.00 94.81  ? 219 ASN C C   1 
ATOM 5429 O O   . ASN C 1 145 ? 158.262 148.503 134.056 1.00 94.54  ? 219 ASN C O   1 
ATOM 5430 C CB  . ASN C 1 145 ? 160.114 147.053 132.606 1.00 96.46  ? 219 ASN C CB  1 
ATOM 5431 C CG  . ASN C 1 145 ? 160.702 148.423 132.325 1.00 97.31  ? 219 ASN C CG  1 
ATOM 5432 O OD1 . ASN C 1 145 ? 161.246 149.072 133.218 1.00 96.69  ? 219 ASN C OD1 1 
ATOM 5433 N ND2 . ASN C 1 145 ? 160.594 148.869 131.079 1.00 97.40  ? 219 ASN C ND2 1 
ATOM 5434 N N   . PHE C 1 146 ? 158.471 147.297 135.947 1.00 93.89  ? 220 PHE C N   1 
ATOM 5435 C CA  . PHE C 1 146 ? 157.371 147.997 136.599 1.00 94.53  ? 220 PHE C CA  1 
ATOM 5436 C C   . PHE C 1 146 ? 157.698 149.464 136.848 1.00 95.73  ? 220 PHE C C   1 
ATOM 5437 O O   . PHE C 1 146 ? 156.787 150.297 136.887 1.00 97.11  ? 220 PHE C O   1 
ATOM 5438 C CB  . PHE C 1 146 ? 157.000 147.299 137.908 1.00 95.13  ? 220 PHE C CB  1 
ATOM 5439 C CG  . PHE C 1 146 ? 158.016 147.466 139.002 1.00 95.75  ? 220 PHE C CG  1 
ATOM 5440 C CD1 . PHE C 1 146 ? 159.111 146.623 139.081 1.00 97.03  ? 220 PHE C CD1 1 
ATOM 5441 C CD2 . PHE C 1 146 ? 157.869 148.456 139.960 1.00 96.10  ? 220 PHE C CD2 1 
ATOM 5442 C CE1 . PHE C 1 146 ? 160.044 146.768 140.090 1.00 98.27  ? 220 PHE C CE1 1 
ATOM 5443 C CE2 . PHE C 1 146 ? 158.800 148.608 140.969 1.00 97.26  ? 220 PHE C CE2 1 
ATOM 5444 C CZ  . PHE C 1 146 ? 159.889 147.763 141.034 1.00 97.81  ? 220 PHE C CZ  1 
ATOM 5445 N N   . GLN C 1 147 ? 158.979 149.800 137.019 1.00 99.21  ? 221 GLN C N   1 
ATOM 5446 C CA  . GLN C 1 147 ? 159.346 151.191 137.266 1.00 98.39  ? 221 GLN C CA  1 
ATOM 5447 C C   . GLN C 1 147 ? 158.947 152.079 136.095 1.00 97.36  ? 221 GLN C C   1 
ATOM 5448 O O   . GLN C 1 147 ? 158.376 153.159 136.285 1.00 99.21  ? 221 GLN C O   1 
ATOM 5449 C CB  . GLN C 1 147 ? 160.847 151.305 137.535 1.00 96.03  ? 221 GLN C CB  1 
ATOM 5450 C CG  . GLN C 1 147 ? 161.340 150.538 138.750 1.00 94.91  ? 221 GLN C CG  1 
ATOM 5451 C CD  . GLN C 1 147 ? 161.780 149.128 138.411 1.00 97.89  ? 221 GLN C CD  1 
ATOM 5452 O OE1 . GLN C 1 147 ? 161.406 148.580 137.373 1.00 98.60  ? 221 GLN C OE1 1 
ATOM 5453 N NE2 . GLN C 1 147 ? 162.589 148.536 139.281 1.00 98.57  ? 221 GLN C NE2 1 
ATOM 5454 N N   . SER C 1 148 ? 159.236 151.636 134.870 1.00 96.81  ? 222 SER C N   1 
ATOM 5455 C CA  . SER C 1 148 ? 158.885 152.430 133.697 1.00 98.35  ? 222 SER C CA  1 
ATOM 5456 C C   . SER C 1 148 ? 157.374 152.540 133.533 1.00 98.49  ? 222 SER C C   1 
ATOM 5457 O O   . SER C 1 148 ? 156.856 153.613 133.203 1.00 98.75  ? 222 SER C O   1 
ATOM 5458 C CB  . SER C 1 148 ? 159.519 151.825 132.446 1.00 97.07  ? 222 SER C CB  1 
ATOM 5459 O OG  . SER C 1 148 ? 159.177 152.570 131.289 1.00 96.47  ? 222 SER C OG  1 
ATOM 5460 N N   . GLN C 1 149 ? 156.653 151.439 133.756 1.00 91.16  ? 223 GLN C N   1 
ATOM 5461 C CA  . GLN C 1 149 ? 155.207 151.444 133.562 1.00 89.40  ? 223 GLN C CA  1 
ATOM 5462 C C   . GLN C 1 149 ? 154.511 152.341 134.578 1.00 90.97  ? 223 GLN C C   1 
ATOM 5463 O O   . GLN C 1 149 ? 153.573 153.068 134.231 1.00 92.16  ? 223 GLN C O   1 
ATOM 5464 C CB  . GLN C 1 149 ? 154.669 150.017 133.644 1.00 86.43  ? 223 GLN C CB  1 
ATOM 5465 C CG  . GLN C 1 149 ? 155.288 149.071 132.633 1.00 83.93  ? 223 GLN C CG  1 
ATOM 5466 C CD  . GLN C 1 149 ? 154.746 147.663 132.748 1.00 89.29  ? 223 GLN C CD  1 
ATOM 5467 O OE1 . GLN C 1 149 ? 153.866 147.390 133.563 1.00 93.10  ? 223 GLN C OE1 1 
ATOM 5468 N NE2 . GLN C 1 149 ? 155.273 146.757 131.934 1.00 90.24  ? 223 GLN C NE2 1 
ATOM 5469 N N   . VAL C 1 150 ? 154.951 152.303 135.837 1.00 84.87  ? 224 VAL C N   1 
ATOM 5470 C CA  . VAL C 1 150 ? 154.316 153.117 136.869 1.00 85.97  ? 224 VAL C CA  1 
ATOM 5471 C C   . VAL C 1 150 ? 154.571 154.598 136.617 1.00 82.57  ? 224 VAL C C   1 
ATOM 5472 O O   . VAL C 1 150 ? 153.674 155.432 136.789 1.00 85.10  ? 224 VAL C O   1 
ATOM 5473 C CB  . VAL C 1 150 ? 154.798 152.684 138.265 1.00 90.29  ? 224 VAL C CB  1 
ATOM 5474 C CG1 . VAL C 1 150 ? 154.305 153.655 139.323 1.00 89.98  ? 224 VAL C CG1 1 
ATOM 5475 C CG2 . VAL C 1 150 ? 154.309 151.280 138.578 1.00 91.27  ? 224 VAL C CG2 1 
ATOM 5476 N N   . THR C 1 151 ? 155.790 154.949 136.203 1.00 85.48  ? 225 THR C N   1 
ATOM 5477 C CA  . THR C 1 151 ? 156.102 156.350 135.936 1.00 90.45  ? 225 THR C CA  1 
ATOM 5478 C C   . THR C 1 151 ? 155.257 156.899 134.795 1.00 92.98  ? 225 THR C C   1 
ATOM 5479 O O   . THR C 1 151 ? 154.848 158.066 134.821 1.00 93.73  ? 225 THR C O   1 
ATOM 5480 C CB  . THR C 1 151 ? 157.590 156.512 135.625 1.00 93.77  ? 225 THR C CB  1 
ATOM 5481 O OG1 . THR C 1 151 ? 157.972 155.587 134.600 1.00 91.78  ? 225 THR C OG1 1 
ATOM 5482 C CG2 . THR C 1 151 ? 158.429 156.275 136.874 1.00 94.41  ? 225 THR C CG2 1 
ATOM 5483 N N   . GLN C 1 152 ? 154.990 156.076 133.779 1.00 98.08  ? 226 GLN C N   1 
ATOM 5484 C CA  . GLN C 1 152 ? 154.154 156.524 132.669 1.00 96.97  ? 226 GLN C CA  1 
ATOM 5485 C C   . GLN C 1 152 ? 152.734 156.824 133.133 1.00 98.18  ? 226 GLN C C   1 
ATOM 5486 O O   . GLN C 1 152 ? 152.126 157.808 132.697 1.00 99.77  ? 226 GLN C O   1 
ATOM 5487 C CB  . GLN C 1 152 ? 154.149 155.474 131.558 1.00 94.02  ? 226 GLN C CB  1 
ATOM 5488 C CG  . GLN C 1 152 ? 153.569 155.972 130.245 1.00 96.62  ? 226 GLN C CG  1 
ATOM 5489 C CD  . GLN C 1 152 ? 153.788 154.998 129.105 1.00 99.68  ? 226 GLN C CD  1 
ATOM 5490 O OE1 . GLN C 1 152 ? 154.318 153.905 129.300 1.00 99.14  ? 226 GLN C OE1 1 
ATOM 5491 N NE2 . GLN C 1 152 ? 153.379 155.392 127.904 1.00 99.81  ? 226 GLN C NE2 1 
ATOM 5492 N N   . VAL C 1 153 ? 152.184 155.983 134.011 1.00 83.85  ? 227 VAL C N   1 
ATOM 5493 C CA  . VAL C 1 153 ? 150.837 156.220 134.523 1.00 77.43  ? 227 VAL C CA  1 
ATOM 5494 C C   . VAL C 1 153 ? 150.798 157.487 135.369 1.00 78.44  ? 227 VAL C C   1 
ATOM 5495 O O   . VAL C 1 153 ? 149.872 158.299 135.254 1.00 75.67  ? 227 VAL C O   1 
ATOM 5496 C CB  . VAL C 1 153 ? 150.345 154.996 135.314 1.00 76.18  ? 227 VAL C CB  1 
ATOM 5497 C CG1 . VAL C 1 153 ? 149.087 155.337 136.089 1.00 78.05  ? 227 VAL C CG1 1 
ATOM 5498 C CG2 . VAL C 1 153 ? 150.099 153.828 134.377 1.00 81.91  ? 227 VAL C CG2 1 
ATOM 5499 N N   . ILE C 1 154 ? 151.797 157.676 136.231 1.00 95.90  ? 228 ILE C N   1 
ATOM 5500 C CA  . ILE C 1 154 ? 151.825 158.851 137.098 1.00 94.29  ? 228 ILE C CA  1 
ATOM 5501 C C   . ILE C 1 154 ? 151.980 160.123 136.275 1.00 93.63  ? 228 ILE C C   1 
ATOM 5502 O O   . ILE C 1 154 ? 151.252 161.103 136.473 1.00 95.88  ? 228 ILE C O   1 
ATOM 5503 C CB  . ILE C 1 154 ? 152.946 158.718 138.144 1.00 93.18  ? 228 ILE C CB  1 
ATOM 5504 C CG1 . ILE C 1 154 ? 152.716 157.489 139.026 1.00 91.14  ? 228 ILE C CG1 1 
ATOM 5505 C CG2 . ILE C 1 154 ? 153.051 159.980 138.984 1.00 94.55  ? 228 ILE C CG2 1 
ATOM 5506 C CD1 . ILE C 1 154 ? 153.831 157.234 140.010 1.00 92.11  ? 228 ILE C CD1 1 
ATOM 5507 N N   . GLU C 1 155 ? 152.924 160.128 135.335 1.00 100.80 ? 229 GLU C N   1 
ATOM 5508 C CA  . GLU C 1 155 ? 153.239 161.339 134.584 1.00 102.90 ? 229 GLU C CA  1 
ATOM 5509 C C   . GLU C 1 155 ? 152.388 161.465 133.324 1.00 105.83 ? 229 GLU C C   1 
ATOM 5510 O O   . GLU C 1 155 ? 151.653 162.444 133.159 1.00 106.61 ? 229 GLU C O   1 
ATOM 5511 C CB  . GLU C 1 155 ? 154.732 161.361 134.233 1.00 103.41 ? 229 GLU C CB  1 
ATOM 5512 C CG  . GLU C 1 155 ? 155.651 161.375 135.445 1.00 105.74 ? 229 GLU C CG  1 
ATOM 5513 C CD  . GLU C 1 155 ? 157.116 161.301 135.066 1.00 106.81 ? 229 GLU C CD  1 
ATOM 5514 O OE1 . GLU C 1 155 ? 157.414 161.002 133.891 1.00 105.75 ? 229 GLU C OE1 1 
ATOM 5515 O OE2 . GLU C 1 155 ? 157.972 161.541 135.944 1.00 107.00 ? 229 GLU C OE2 1 
ATOM 5516 N N   . GLY C 1 156 ? 152.475 160.483 132.431 1.00 109.30 ? 230 GLY C N   1 
ATOM 5517 C CA  . GLY C 1 156 ? 151.755 160.536 131.178 1.00 108.23 ? 230 GLY C CA  1 
ATOM 5518 C C   . GLY C 1 156 ? 150.306 160.114 131.316 1.00 108.98 ? 230 GLY C C   1 
ATOM 5519 O O   . GLY C 1 156 ? 149.806 159.807 132.398 1.00 110.00 ? 230 GLY C O   1 
ATOM 5520 N N   . ASN C 1 157 ? 149.620 160.101 130.178 1.00 113.08 ? 231 ASN C N   1 
ATOM 5521 C CA  . ASN C 1 157 ? 148.216 159.727 130.102 1.00 115.36 ? 231 ASN C CA  1 
ATOM 5522 C C   . ASN C 1 157 ? 148.102 158.302 129.581 1.00 113.43 ? 231 ASN C C   1 
ATOM 5523 O O   . ASN C 1 157 ? 148.768 157.939 128.606 1.00 111.75 ? 231 ASN C O   1 
ATOM 5524 C CB  . ASN C 1 157 ? 147.441 160.686 129.195 1.00 115.44 ? 231 ASN C CB  1 
ATOM 5525 C CG  . ASN C 1 157 ? 147.459 162.113 129.707 1.00 116.60 ? 231 ASN C CG  1 
ATOM 5526 O OD1 . ASN C 1 157 ? 148.314 162.487 130.510 1.00 116.98 ? 231 ASN C OD1 1 
ATOM 5527 N ND2 . ASN C 1 157 ? 146.514 162.921 129.240 1.00 115.84 ? 231 ASN C ND2 1 
ATOM 5528 N N   . ALA C 1 158 ? 147.268 157.501 130.234 1.00 104.51 ? 232 ALA C N   1 
ATOM 5529 C CA  . ALA C 1 158 ? 147.026 156.120 129.847 1.00 104.35 ? 232 ALA C CA  1 
ATOM 5530 C C   . ALA C 1 158 ? 145.552 155.926 129.504 1.00 106.57 ? 232 ALA C C   1 
ATOM 5531 O O   . ALA C 1 158 ? 144.703 156.777 129.783 1.00 107.91 ? 232 ALA C O   1 
ATOM 5532 C CB  . ALA C 1 158 ? 147.468 155.168 130.959 1.00 101.83 ? 232 ALA C CB  1 
ATOM 5533 N N   . ALA C 1 159 ? 145.251 154.785 128.890 1.00 98.88  ? 233 ALA C N   1 
ATOM 5534 C CA  . ALA C 1 159 ? 143.896 154.445 128.487 1.00 93.06  ? 233 ALA C CA  1 
ATOM 5535 C C   . ALA C 1 159 ? 143.201 153.682 129.606 1.00 95.44  ? 233 ALA C C   1 
ATOM 5536 O O   . ALA C 1 159 ? 143.822 152.865 130.292 1.00 97.83  ? 233 ALA C O   1 
ATOM 5537 C CB  . ALA C 1 159 ? 143.898 153.610 127.206 1.00 90.96  ? 233 ALA C CB  1 
ATOM 5538 N N   . VAL C 1 160 ? 141.908 153.953 129.785 1.00 81.21  ? 234 VAL C N   1 
ATOM 5539 C CA  . VAL C 1 160 ? 141.136 153.365 130.869 1.00 81.83  ? 234 VAL C CA  1 
ATOM 5540 C C   . VAL C 1 160 ? 139.852 152.762 130.316 1.00 80.53  ? 234 VAL C C   1 
ATOM 5541 O O   . VAL C 1 160 ? 139.367 153.138 129.248 1.00 78.97  ? 234 VAL C O   1 
ATOM 5542 C CB  . VAL C 1 160 ? 140.806 154.393 131.971 1.00 78.51  ? 234 VAL C CB  1 
ATOM 5543 C CG1 . VAL C 1 160 ? 142.060 154.765 132.744 1.00 80.75  ? 234 VAL C CG1 1 
ATOM 5544 C CG2 . VAL C 1 160 ? 140.162 155.626 131.365 1.00 76.24  ? 234 VAL C CG2 1 
ATOM 5545 N N   . VAL C 1 161 ? 139.309 151.809 131.068 1.00 75.89  ? 235 VAL C N   1 
ATOM 5546 C CA  . VAL C 1 161 ? 138.001 151.222 130.802 1.00 72.83  ? 235 VAL C CA  1 
ATOM 5547 C C   . VAL C 1 161 ? 137.124 151.494 132.014 1.00 72.56  ? 235 VAL C C   1 
ATOM 5548 O O   . VAL C 1 161 ? 137.441 151.055 133.126 1.00 74.03  ? 235 VAL C O   1 
ATOM 5549 C CB  . VAL C 1 161 ? 138.090 149.715 130.523 1.00 70.85  ? 235 VAL C CB  1 
ATOM 5550 C CG1 . VAL C 1 161 ? 136.700 149.122 130.389 1.00 70.00  ? 235 VAL C CG1 1 
ATOM 5551 C CG2 . VAL C 1 161 ? 138.893 149.460 129.270 1.00 71.16  ? 235 VAL C CG2 1 
ATOM 5552 N N   . LEU C 1 162 ? 136.025 152.214 131.802 1.00 59.00  ? 236 LEU C N   1 
ATOM 5553 C CA  . LEU C 1 162 ? 135.108 152.558 132.886 1.00 55.75  ? 236 LEU C CA  1 
ATOM 5554 C C   . LEU C 1 162 ? 134.204 151.361 133.146 1.00 58.37  ? 236 LEU C C   1 
ATOM 5555 O O   . LEU C 1 162 ? 133.132 151.220 132.557 1.00 60.96  ? 236 LEU C O   1 
ATOM 5556 C CB  . LEU C 1 162 ? 134.309 153.806 132.539 1.00 59.44  ? 236 LEU C CB  1 
ATOM 5557 C CG  . LEU C 1 162 ? 135.129 155.081 132.355 1.00 60.51  ? 236 LEU C CG  1 
ATOM 5558 C CD1 . LEU C 1 162 ? 134.220 156.261 132.061 1.00 58.08  ? 236 LEU C CD1 1 
ATOM 5559 C CD2 . LEU C 1 162 ? 135.975 155.349 133.586 1.00 59.47  ? 236 LEU C CD2 1 
ATOM 5560 N N   . ARG C 1 163 ? 134.648 150.488 134.045 1.00 58.81  ? 237 ARG C N   1 
ATOM 5561 C CA  . ARG C 1 163 ? 133.908 149.271 134.342 1.00 62.64  ? 237 ARG C CA  1 
ATOM 5562 C C   . ARG C 1 163 ? 132.606 149.611 135.054 1.00 63.94  ? 237 ARG C C   1 
ATOM 5563 O O   . ARG C 1 163 ? 132.596 150.385 136.015 1.00 67.56  ? 237 ARG C O   1 
ATOM 5564 C CB  . ARG C 1 163 ? 134.755 148.341 135.207 1.00 65.33  ? 237 ARG C CB  1 
ATOM 5565 C CG  . ARG C 1 163 ? 136.090 147.963 134.590 1.00 66.40  ? 237 ARG C CG  1 
ATOM 5566 C CD  . ARG C 1 163 ? 135.916 147.092 133.367 1.00 64.48  ? 237 ARG C CD  1 
ATOM 5567 N NE  . ARG C 1 163 ? 137.196 146.741 132.768 1.00 62.96  ? 237 ARG C NE  1 
ATOM 5568 C CZ  . ARG C 1 163 ? 137.903 145.669 133.093 1.00 62.84  ? 237 ARG C CZ  1 
ATOM 5569 N NH1 . ARG C 1 163 ? 137.485 144.823 134.017 1.00 67.64  ? 237 ARG C NH1 1 
ATOM 5570 N NH2 . ARG C 1 163 ? 139.059 145.442 132.476 1.00 65.28  ? 237 ARG C NH2 1 
ATOM 5571 N N   . SER C 1 164 ? 131.508 149.029 134.586 1.00 50.97  ? 238 SER C N   1 
ATOM 5572 C CA  . SER C 1 164 ? 130.210 149.286 135.187 1.00 49.02  ? 238 SER C CA  1 
ATOM 5573 C C   . SER C 1 164 ? 130.058 148.522 136.496 1.00 55.37  ? 238 SER C C   1 
ATOM 5574 O O   . SER C 1 164 ? 130.647 147.455 136.690 1.00 65.42  ? 238 SER C O   1 
ATOM 5575 C CB  . SER C 1 164 ? 129.089 148.899 134.225 1.00 56.78  ? 238 SER C CB  1 
ATOM 5576 O OG  . SER C 1 164 ? 129.205 149.603 133.000 1.00 60.81  ? 238 SER C OG  1 
ATOM 5577 N N   . ARG C 1 165 ? 129.255 149.080 137.398 1.00 49.25  ? 239 ARG C N   1 
ATOM 5578 C CA  . ARG C 1 165 ? 128.944 148.455 138.674 1.00 40.96  ? 239 ARG C CA  1 
ATOM 5579 C C   . ARG C 1 165 ? 127.450 148.567 138.946 1.00 48.04  ? 239 ARG C C   1 
ATOM 5580 O O   . ARG C 1 165 ? 126.733 149.336 138.301 1.00 55.08  ? 239 ARG C O   1 
ATOM 5581 C CB  . ARG C 1 165 ? 129.748 149.077 139.822 1.00 43.58  ? 239 ARG C CB  1 
ATOM 5582 C CG  . ARG C 1 165 ? 131.240 148.822 139.732 1.00 52.40  ? 239 ARG C CG  1 
ATOM 5583 C CD  . ARG C 1 165 ? 131.930 149.083 141.056 1.00 48.10  ? 239 ARG C CD  1 
ATOM 5584 N NE  . ARG C 1 165 ? 131.840 150.481 141.455 1.00 44.68  ? 239 ARG C NE  1 
ATOM 5585 C CZ  . ARG C 1 165 ? 132.363 150.973 142.569 1.00 55.25  ? 239 ARG C CZ  1 
ATOM 5586 N NH1 . ARG C 1 165 ? 133.018 150.205 143.423 1.00 59.08  ? 239 ARG C NH1 1 
ATOM 5587 N NH2 . ARG C 1 165 ? 132.224 152.269 142.833 1.00 57.81  ? 239 ARG C NH2 1 
ATOM 5588 N N   . LEU C 1 166 ? 126.982 147.785 139.916 1.00 54.99  ? 240 LEU C N   1 
ATOM 5589 C CA  . LEU C 1 166 ? 125.564 147.662 140.224 1.00 56.08  ? 240 LEU C CA  1 
ATOM 5590 C C   . LEU C 1 166 ? 125.287 148.148 141.640 1.00 56.18  ? 240 LEU C C   1 
ATOM 5591 O O   . LEU C 1 166 ? 125.953 147.720 142.588 1.00 57.28  ? 240 LEU C O   1 
ATOM 5592 C CB  . LEU C 1 166 ? 125.100 146.212 140.073 1.00 48.78  ? 240 LEU C CB  1 
ATOM 5593 C CG  . LEU C 1 166 ? 125.097 145.654 138.652 1.00 50.26  ? 240 LEU C CG  1 
ATOM 5594 C CD1 . LEU C 1 166 ? 124.757 144.178 138.654 1.00 53.67  ? 240 LEU C CD1 1 
ATOM 5595 C CD2 . LEU C 1 166 ? 124.130 146.431 137.774 1.00 52.62  ? 240 LEU C CD2 1 
ATOM 5596 N N   . LYS C 1 167 ? 124.301 149.031 141.780 1.00 52.96  ? 241 LYS C N   1 
ATOM 5597 C CA  . LYS C 1 167 ? 123.838 149.490 143.088 1.00 45.50  ? 241 LYS C CA  1 
ATOM 5598 C C   . LYS C 1 167 ? 122.762 148.526 143.567 1.00 50.59  ? 241 LYS C C   1 
ATOM 5599 O O   . LYS C 1 167 ? 121.596 148.634 143.180 1.00 60.13  ? 241 LYS C O   1 
ATOM 5600 C CB  . LYS C 1 167 ? 123.308 150.917 143.016 1.00 48.25  ? 241 LYS C CB  1 
ATOM 5601 C CG  . LYS C 1 167 ? 124.375 151.970 142.795 1.00 53.63  ? 241 LYS C CG  1 
ATOM 5602 C CD  . LYS C 1 167 ? 123.773 153.365 142.740 1.00 55.38  ? 241 LYS C CD  1 
ATOM 5603 C CE  . LYS C 1 167 ? 124.848 154.421 142.539 1.00 61.10  ? 241 LYS C CE  1 
ATOM 5604 N NZ  . LYS C 1 167 ? 125.808 154.453 143.676 1.00 60.41  ? 241 LYS C NZ  1 
ATOM 5605 N N   . VAL C 1 168 ? 123.153 147.582 144.413 1.00 43.97  ? 242 VAL C N   1 
ATOM 5606 C CA  . VAL C 1 168 ? 122.257 146.546 144.907 1.00 47.98  ? 242 VAL C CA  1 
ATOM 5607 C C   . VAL C 1 168 ? 121.745 146.964 146.277 1.00 54.61  ? 242 VAL C C   1 
ATOM 5608 O O   . VAL C 1 168 ? 122.536 147.251 147.183 1.00 55.27  ? 242 VAL C O   1 
ATOM 5609 C CB  . VAL C 1 168 ? 122.963 145.185 144.973 1.00 48.21  ? 242 VAL C CB  1 
ATOM 5610 C CG1 . VAL C 1 168 ? 122.057 144.168 145.607 1.00 51.11  ? 242 VAL C CG1 1 
ATOM 5611 C CG2 . VAL C 1 168 ? 123.383 144.739 143.582 1.00 55.19  ? 242 VAL C CG2 1 
ATOM 5612 N N   . ARG C 1 169 ? 120.425 146.998 146.430 1.00 55.50  ? 243 ARG C N   1 
ATOM 5613 C CA  . ARG C 1 169 ? 119.782 147.372 147.682 1.00 46.69  ? 243 ARG C CA  1 
ATOM 5614 C C   . ARG C 1 169 ? 118.884 146.236 148.145 1.00 51.45  ? 243 ARG C C   1 
ATOM 5615 O O   . ARG C 1 169 ? 118.036 145.759 147.384 1.00 59.90  ? 243 ARG C O   1 
ATOM 5616 C CB  . ARG C 1 169 ? 118.973 148.660 147.519 1.00 55.45  ? 243 ARG C CB  1 
ATOM 5617 C CG  . ARG C 1 169 ? 118.145 149.030 148.734 1.00 60.16  ? 243 ARG C CG  1 
ATOM 5618 C CD  . ARG C 1 169 ? 117.627 150.456 148.634 1.00 57.16  ? 243 ARG C CD  1 
ATOM 5619 N NE  . ARG C 1 169 ? 117.046 150.739 147.328 1.00 61.30  ? 243 ARG C NE  1 
ATOM 5620 C CZ  . ARG C 1 169 ? 115.766 150.571 147.025 1.00 62.10  ? 243 ARG C CZ  1 
ATOM 5621 N NH1 . ARG C 1 169 ? 114.898 150.122 147.916 1.00 59.92  ? 243 ARG C NH1 1 
ATOM 5622 N NH2 . ARG C 1 169 ? 115.347 150.863 145.797 1.00 61.85  ? 243 ARG C NH2 1 
ATOM 5623 N N   . VAL C 1 170 ? 119.069 145.807 149.390 1.00 46.41  ? 244 VAL C N   1 
ATOM 5624 C CA  . VAL C 1 170 ? 118.292 144.727 149.987 1.00 39.74  ? 244 VAL C CA  1 
ATOM 5625 C C   . VAL C 1 170 ? 117.390 145.333 151.051 1.00 47.17  ? 244 VAL C C   1 
ATOM 5626 O O   . VAL C 1 170 ? 117.868 146.012 151.967 1.00 57.61  ? 244 VAL C O   1 
ATOM 5627 C CB  . VAL C 1 170 ? 119.196 143.639 150.584 1.00 43.43  ? 244 VAL C CB  1 
ATOM 5628 C CG1 . VAL C 1 170 ? 118.357 142.516 151.162 1.00 48.93  ? 244 VAL C CG1 1 
ATOM 5629 C CG2 . VAL C 1 170 ? 120.150 143.107 149.531 1.00 49.94  ? 244 VAL C CG2 1 
ATOM 5630 N N   . VAL C 1 171 ? 116.089 145.090 150.930 1.00 56.99  ? 245 VAL C N   1 
ATOM 5631 C CA  . VAL C 1 171 ? 115.089 145.640 151.836 1.00 61.18  ? 245 VAL C CA  1 
ATOM 5632 C C   . VAL C 1 171 ? 114.441 144.491 152.591 1.00 65.90  ? 245 VAL C C   1 
ATOM 5633 O O   . VAL C 1 171 ? 113.988 143.515 151.981 1.00 65.18  ? 245 VAL C O   1 
ATOM 5634 C CB  . VAL C 1 171 ? 114.034 146.466 151.081 1.00 59.16  ? 245 VAL C CB  1 
ATOM 5635 C CG1 . VAL C 1 171 ? 113.042 147.077 152.056 1.00 59.85  ? 245 VAL C CG1 1 
ATOM 5636 C CG2 . VAL C 1 171 ? 114.706 147.547 150.251 1.00 56.64  ? 245 VAL C CG2 1 
ATOM 5637 N N   . LYS C 1 172 ? 114.398 144.608 153.913 1.00 64.18  ? 246 LYS C N   1 
ATOM 5638 C CA  . LYS C 1 172 ? 113.824 143.590 154.777 1.00 52.64  ? 246 LYS C CA  1 
ATOM 5639 C C   . LYS C 1 172 ? 112.430 144.002 155.234 1.00 57.75  ? 246 LYS C C   1 
ATOM 5640 O O   . LYS C 1 172 ? 112.028 145.162 155.118 1.00 62.02  ? 246 LYS C O   1 
ATOM 5641 C CB  . LYS C 1 172 ? 114.724 143.346 155.990 1.00 53.13  ? 246 LYS C CB  1 
ATOM 5642 C CG  . LYS C 1 172 ? 116.101 142.817 155.637 1.00 57.18  ? 246 LYS C CG  1 
ATOM 5643 C CD  . LYS C 1 172 ? 116.065 141.328 155.360 1.00 54.13  ? 246 LYS C CD  1 
ATOM 5644 C CE  . LYS C 1 172 ? 117.459 140.780 155.117 1.00 57.12  ? 246 LYS C CE  1 
ATOM 5645 N NZ  . LYS C 1 172 ? 117.456 139.298 154.983 1.00 62.06  ? 246 LYS C NZ  1 
ATOM 5646 N N   . GLU C 1 173 ? 111.692 143.029 155.758 1.00 89.84  ? 247 GLU C N   1 
ATOM 5647 C CA  . GLU C 1 173 ? 110.335 143.270 156.235 1.00 96.33  ? 247 GLU C CA  1 
ATOM 5648 C C   . GLU C 1 173 ? 110.344 144.069 157.534 1.00 100.00 ? 247 GLU C C   1 
ATOM 5649 O O   . GLU C 1 173 ? 109.435 144.858 157.795 1.00 103.31 ? 247 GLU C O   1 
ATOM 5650 C CB  . GLU C 1 173 ? 109.591 141.944 156.425 1.00 97.28  ? 247 GLU C CB  1 
ATOM 5651 C CG  . GLU C 1 173 ? 110.224 140.994 157.436 1.00 103.77 ? 247 GLU C CG  1 
ATOM 5652 C CD  . GLU C 1 173 ? 109.755 141.246 158.858 1.00 109.15 ? 247 GLU C CD  1 
ATOM 5653 O OE1 . GLU C 1 173 ? 108.691 141.875 159.032 1.00 108.32 ? 247 GLU C OE1 1 
ATOM 5654 O OE2 . GLU C 1 173 ? 110.453 140.816 159.800 1.00 110.13 ? 247 GLU C OE2 1 
ATOM 5655 N N   . ALA C 1 203 ? 117.951 148.799 155.717 1.00 84.17  ? 277 ALA C N   1 
ATOM 5656 C CA  . ALA C 1 203 ? 118.431 148.801 154.340 1.00 86.92  ? 277 ALA C CA  1 
ATOM 5657 C C   . ALA C 1 203 ? 119.949 148.669 154.289 1.00 85.62  ? 277 ALA C C   1 
ATOM 5658 O O   . ALA C 1 203 ? 120.666 149.344 155.028 1.00 83.58  ? 277 ALA C O   1 
ATOM 5659 C CB  . ALA C 1 203 ? 117.984 150.066 153.625 1.00 81.46  ? 277 ALA C CB  1 
ATOM 5660 N N   . MET C 1 204 ? 120.432 147.795 153.410 1.00 70.00  ? 278 MET C N   1 
ATOM 5661 C CA  . MET C 1 204 ? 121.864 147.563 153.240 1.00 65.80  ? 278 MET C CA  1 
ATOM 5662 C C   . MET C 1 204 ? 122.185 147.685 151.758 1.00 71.84  ? 278 MET C C   1 
ATOM 5663 O O   . MET C 1 204 ? 121.749 146.855 150.955 1.00 74.58  ? 278 MET C O   1 
ATOM 5664 C CB  . MET C 1 204 ? 122.272 146.192 153.780 1.00 65.20  ? 278 MET C CB  1 
ATOM 5665 C CG  . MET C 1 204 ? 122.635 146.190 155.256 1.00 70.11  ? 278 MET C CG  1 
ATOM 5666 S SD  . MET C 1 204 ? 124.009 147.293 155.641 1.00 82.73  ? 278 MET C SD  1 
ATOM 5667 C CE  . MET C 1 204 ? 125.282 146.636 154.566 1.00 70.02  ? 278 MET C CE  1 
ATOM 5668 N N   . GLN C 1 205 ? 122.943 148.715 151.400 1.00 60.25  ? 279 GLN C N   1 
ATOM 5669 C CA  . GLN C 1 205 ? 123.276 148.992 150.012 1.00 49.34  ? 279 GLN C CA  1 
ATOM 5670 C C   . GLN C 1 205 ? 124.684 148.503 149.700 1.00 53.60  ? 279 GLN C C   1 
ATOM 5671 O O   . GLN C 1 205 ? 125.603 148.662 150.509 1.00 58.92  ? 279 GLN C O   1 
ATOM 5672 C CB  . GLN C 1 205 ? 123.156 150.490 149.731 1.00 48.01  ? 279 GLN C CB  1 
ATOM 5673 C CG  . GLN C 1 205 ? 123.327 150.877 148.279 1.00 52.19  ? 279 GLN C CG  1 
ATOM 5674 C CD  . GLN C 1 205 ? 123.067 152.349 148.046 1.00 57.83  ? 279 GLN C CD  1 
ATOM 5675 O OE1 . GLN C 1 205 ? 122.671 153.072 148.959 1.00 59.84  ? 279 GLN C OE1 1 
ATOM 5676 N NE2 . GLN C 1 205 ? 123.287 152.803 146.817 1.00 56.70  ? 279 GLN C NE2 1 
ATOM 5677 N N   . TYR C 1 206 ? 124.848 147.904 148.523 1.00 51.92  ? 280 TYR C N   1 
ATOM 5678 C CA  . TYR C 1 206 ? 126.124 147.348 148.099 1.00 47.45  ? 280 TYR C CA  1 
ATOM 5679 C C   . TYR C 1 206 ? 126.463 147.825 146.695 1.00 57.49  ? 280 TYR C C   1 
ATOM 5680 O O   . TYR C 1 206 ? 125.580 148.186 145.912 1.00 65.69  ? 280 TYR C O   1 
ATOM 5681 C CB  . TYR C 1 206 ? 126.108 145.816 148.108 1.00 46.07  ? 280 TYR C CB  1 
ATOM 5682 C CG  . TYR C 1 206 ? 125.751 145.191 149.434 1.00 50.46  ? 280 TYR C CG  1 
ATOM 5683 C CD1 . TYR C 1 206 ? 126.691 145.077 150.447 1.00 56.51  ? 280 TYR C CD1 1 
ATOM 5684 C CD2 . TYR C 1 206 ? 124.476 144.698 149.666 1.00 54.81  ? 280 TYR C CD2 1 
ATOM 5685 C CE1 . TYR C 1 206 ? 126.368 144.497 151.658 1.00 55.61  ? 280 TYR C CE1 1 
ATOM 5686 C CE2 . TYR C 1 206 ? 124.143 144.117 150.872 1.00 59.16  ? 280 TYR C CE2 1 
ATOM 5687 C CZ  . TYR C 1 206 ? 125.092 144.019 151.865 1.00 58.82  ? 280 TYR C CZ  1 
ATOM 5688 O OH  . TYR C 1 206 ? 124.762 143.440 153.068 1.00 57.32  ? 280 TYR C OH  1 
ATOM 5689 N N   . GLN C 1 207 ? 127.756 147.820 146.386 1.00 50.86  ? 281 GLN C N   1 
ATOM 5690 C CA  . GLN C 1 207 ? 128.255 148.037 145.036 1.00 46.25  ? 281 GLN C CA  1 
ATOM 5691 C C   . GLN C 1 207 ? 128.947 146.766 144.568 1.00 44.45  ? 281 GLN C C   1 
ATOM 5692 O O   . GLN C 1 207 ? 129.856 146.266 145.240 1.00 55.00  ? 281 GLN C O   1 
ATOM 5693 C CB  . GLN C 1 207 ? 129.223 149.220 144.988 1.00 48.38  ? 281 GLN C CB  1 
ATOM 5694 C CG  . GLN C 1 207 ? 128.657 150.519 145.536 1.00 49.63  ? 281 GLN C CG  1 
ATOM 5695 C CD  . GLN C 1 207 ? 127.528 151.077 144.696 1.00 58.58  ? 281 GLN C CD  1 
ATOM 5696 O OE1 . GLN C 1 207 ? 126.649 151.773 145.203 1.00 58.33  ? 281 GLN C OE1 1 
ATOM 5697 N NE2 . GLN C 1 207 ? 127.551 150.785 143.401 1.00 57.99  ? 281 GLN C NE2 1 
ATOM 5698 N N   . VAL C 1 208 ? 128.519 146.246 143.424 1.00 45.52  ? 282 VAL C N   1 
ATOM 5699 C CA  . VAL C 1 208 ? 128.985 144.964 142.910 1.00 45.30  ? 282 VAL C CA  1 
ATOM 5700 C C   . VAL C 1 208 ? 129.628 145.187 141.549 1.00 50.35  ? 282 VAL C C   1 
ATOM 5701 O O   . VAL C 1 208 ? 129.028 145.814 140.669 1.00 59.89  ? 282 VAL C O   1 
ATOM 5702 C CB  . VAL C 1 208 ? 127.835 143.948 142.810 1.00 53.35  ? 282 VAL C CB  1 
ATOM 5703 C CG1 . VAL C 1 208 ? 128.315 142.679 142.150 1.00 54.50  ? 282 VAL C CG1 1 
ATOM 5704 C CG2 . VAL C 1 208 ? 127.270 143.654 144.191 1.00 57.21  ? 282 VAL C CG2 1 
ATOM 5705 N N   . LEU C 1 209 ? 130.843 144.668 141.379 1.00 50.31  ? 283 LEU C N   1 
ATOM 5706 C CA  . LEU C 1 209 ? 131.581 144.817 140.132 1.00 48.07  ? 283 LEU C CA  1 
ATOM 5707 C C   . LEU C 1 209 ? 131.354 143.648 139.181 1.00 45.81  ? 283 LEU C C   1 
ATOM 5708 O O   . LEU C 1 209 ? 131.115 143.857 137.989 1.00 54.63  ? 283 LEU C O   1 
ATOM 5709 C CB  . LEU C 1 209 ? 133.077 144.969 140.420 1.00 52.25  ? 283 LEU C CB  1 
ATOM 5710 C CG  . LEU C 1 209 ? 133.977 145.109 139.193 1.00 48.33  ? 283 LEU C CG  1 
ATOM 5711 C CD1 . LEU C 1 209 ? 133.587 146.327 138.379 1.00 49.19  ? 283 LEU C CD1 1 
ATOM 5712 C CD2 . LEU C 1 209 ? 135.434 145.182 139.609 1.00 55.10  ? 283 LEU C CD2 1 
ATOM 5713 N N   . ASN C 1 210 ? 131.427 142.417 139.684 1.00 51.05  ? 284 ASN C N   1 
ATOM 5714 C CA  . ASN C 1 210 ? 131.291 141.253 138.815 1.00 59.51  ? 284 ASN C CA  1 
ATOM 5715 C C   . ASN C 1 210 ? 129.854 140.743 138.747 1.00 59.93  ? 284 ASN C C   1 
ATOM 5716 O O   . ASN C 1 210 ? 129.246 140.740 137.673 1.00 54.95  ? 284 ASN C O   1 
ATOM 5717 C CB  . ASN C 1 210 ? 132.229 140.130 139.271 1.00 53.42  ? 284 ASN C CB  1 
ATOM 5718 C CG  . ASN C 1 210 ? 133.678 140.407 138.934 1.00 60.32  ? 284 ASN C CG  1 
ATOM 5719 O OD1 . ASN C 1 210 ? 133.985 141.315 138.162 1.00 64.16  ? 284 ASN C OD1 1 
ATOM 5720 N ND2 . ASN C 1 210 ? 134.578 139.606 139.492 1.00 63.71  ? 284 ASN C ND2 1 
ATOM 5721 N N   . GLU C 1 211 ? 129.294 140.325 139.879 1.00 43.80  ? 285 GLU C N   1 
ATOM 5722 C CA  . GLU C 1 211 ? 128.028 139.611 139.832 1.00 38.48  ? 285 GLU C CA  1 
ATOM 5723 C C   . GLU C 1 211 ? 127.386 139.570 141.210 1.00 43.14  ? 285 GLU C C   1 
ATOM 5724 O O   . GLU C 1 211 ? 128.075 139.506 142.231 1.00 47.93  ? 285 GLU C O   1 
ATOM 5725 C CB  . GLU C 1 211 ? 128.231 138.184 139.320 1.00 46.57  ? 285 GLU C CB  1 
ATOM 5726 C CG  . GLU C 1 211 ? 129.273 137.418 140.112 1.00 54.75  ? 285 GLU C CG  1 
ATOM 5727 C CD  . GLU C 1 211 ? 129.862 136.255 139.346 1.00 56.63  ? 285 GLU C CD  1 
ATOM 5728 O OE1 . GLU C 1 211 ? 129.490 136.062 138.170 1.00 62.63  ? 285 GLU C OE1 1 
ATOM 5729 O OE2 . GLU C 1 211 ? 130.706 135.538 139.922 1.00 58.51  ? 285 GLU C OE2 1 
ATOM 5730 N N   . VAL C 1 212 ? 126.057 139.599 141.219 1.00 37.90  ? 286 VAL C N   1 
ATOM 5731 C CA  . VAL C 1 212 ? 125.255 139.258 142.387 1.00 26.07  ? 286 VAL C CA  1 
ATOM 5732 C C   . VAL C 1 212 ? 124.502 137.971 142.070 1.00 39.81  ? 286 VAL C C   1 
ATOM 5733 O O   . VAL C 1 212 ? 123.875 137.854 141.010 1.00 47.32  ? 286 VAL C O   1 
ATOM 5734 C CB  . VAL C 1 212 ? 124.306 140.404 142.785 1.00 25.77  ? 286 VAL C CB  1 
ATOM 5735 C CG1 . VAL C 1 212 ? 123.296 140.701 141.690 1.00 35.38  ? 286 VAL C CG1 1 
ATOM 5736 C CG2 . VAL C 1 212 ? 123.598 140.077 144.085 1.00 37.87  ? 286 VAL C CG2 1 
ATOM 5737 N N   . VAL C 1 213 ? 124.602 136.991 142.963 1.00 35.66  ? 287 VAL C N   1 
ATOM 5738 C CA  . VAL C 1 213 ? 124.086 135.648 142.722 1.00 25.05  ? 287 VAL C CA  1 
ATOM 5739 C C   . VAL C 1 213 ? 123.021 135.336 143.760 1.00 39.39  ? 287 VAL C C   1 
ATOM 5740 O O   . VAL C 1 213 ? 123.242 135.525 144.961 1.00 42.95  ? 287 VAL C O   1 
ATOM 5741 C CB  . VAL C 1 213 ? 125.206 134.593 142.760 1.00 31.25  ? 287 VAL C CB  1 
ATOM 5742 C CG1 . VAL C 1 213 ? 124.648 133.219 142.442 1.00 41.19  ? 287 VAL C CG1 1 
ATOM 5743 C CG2 . VAL C 1 213 ? 126.304 134.955 141.781 1.00 33.67  ? 287 VAL C CG2 1 
ATOM 5744 N N   . ILE C 1 214 ? 121.873 134.855 143.295 1.00 46.33  ? 288 ILE C N   1 
ATOM 5745 C CA  . ILE C 1 214 ? 120.774 134.436 144.155 1.00 37.95  ? 288 ILE C CA  1 
ATOM 5746 C C   . ILE C 1 214 ? 120.576 132.945 143.928 1.00 39.97  ? 288 ILE C C   1 
ATOM 5747 O O   . ILE C 1 214 ? 120.092 132.532 142.869 1.00 51.93  ? 288 ILE C O   1 
ATOM 5748 C CB  . ILE C 1 214 ? 119.485 135.216 143.865 1.00 39.53  ? 288 ILE C CB  1 
ATOM 5749 C CG1 . ILE C 1 214 ? 119.671 136.707 144.153 1.00 49.55  ? 288 ILE C CG1 1 
ATOM 5750 C CG2 . ILE C 1 214 ? 118.336 134.661 144.684 1.00 44.76  ? 288 ILE C CG2 1 
ATOM 5751 C CD1 . ILE C 1 214 ? 120.148 137.517 142.965 1.00 51.65  ? 288 ILE C CD1 1 
ATOM 5752 N N   . ASP C 1 215 ? 120.934 132.134 144.919 1.00 47.62  ? 289 ASP C N   1 
ATOM 5753 C CA  . ASP C 1 215 ? 120.875 130.686 144.772 1.00 44.32  ? 289 ASP C CA  1 
ATOM 5754 C C   . ASP C 1 215 ? 120.709 130.058 146.147 1.00 54.92  ? 289 ASP C C   1 
ATOM 5755 O O   . ASP C 1 215 ? 120.829 130.726 147.177 1.00 61.97  ? 289 ASP C O   1 
ATOM 5756 C CB  . ASP C 1 215 ? 122.125 130.143 144.077 1.00 43.95  ? 289 ASP C CB  1 
ATOM 5757 C CG  . ASP C 1 215 ? 123.389 130.410 144.865 1.00 61.70  ? 289 ASP C CG  1 
ATOM 5758 O OD1 . ASP C 1 215 ? 123.445 131.436 145.575 1.00 66.51  ? 289 ASP C OD1 1 
ATOM 5759 O OD2 . ASP C 1 215 ? 124.329 129.591 144.777 1.00 64.71  ? 289 ASP C OD2 1 
ATOM 5760 N N   . ARG C 1 216 ? 120.422 128.759 146.148 1.00 75.80  ? 290 ARG C N   1 
ATOM 5761 C CA  . ARG C 1 216 ? 120.295 128.027 147.400 1.00 74.51  ? 290 ARG C CA  1 
ATOM 5762 C C   . ARG C 1 216 ? 121.644 127.940 148.104 1.00 73.50  ? 290 ARG C C   1 
ATOM 5763 O O   . ARG C 1 216 ? 122.697 127.879 147.463 1.00 80.97  ? 290 ARG C O   1 
ATOM 5764 C CB  . ARG C 1 216 ? 119.744 126.625 147.151 1.00 74.85  ? 290 ARG C CB  1 
ATOM 5765 C CG  . ARG C 1 216 ? 120.672 125.715 146.369 1.00 76.77  ? 290 ARG C CG  1 
ATOM 5766 C CD  . ARG C 1 216 ? 120.024 124.365 146.109 1.00 79.06  ? 290 ARG C CD  1 
ATOM 5767 N NE  . ARG C 1 216 ? 120.928 123.446 145.428 1.00 85.24  ? 290 ARG C NE  1 
ATOM 5768 C CZ  . ARG C 1 216 ? 121.058 123.365 144.112 1.00 82.69  ? 290 ARG C CZ  1 
ATOM 5769 N NH1 . ARG C 1 216 ? 120.350 124.133 143.300 1.00 78.44  ? 290 ARG C NH1 1 
ATOM 5770 N NH2 . ARG C 1 216 ? 121.917 122.490 143.597 1.00 80.61  ? 290 ARG C NH2 1 
ATOM 5771 N N   . GLY C 1 217 ? 121.608 127.944 149.433 1.00 68.10  ? 291 GLY C N   1 
ATOM 5772 C CA  . GLY C 1 217 ? 122.812 127.900 150.226 1.00 74.49  ? 291 GLY C CA  1 
ATOM 5773 C C   . GLY C 1 217 ? 122.924 126.625 151.032 1.00 76.63  ? 291 GLY C C   1 
ATOM 5774 O O   . GLY C 1 217 ? 122.971 125.518 150.486 1.00 72.18  ? 291 GLY C O   1 
ATOM 5775 N N   . PRO C 1 218 ? 122.964 126.754 152.357 1.00 71.65  ? 292 PRO C N   1 
ATOM 5776 C CA  . PRO C 1 218 ? 123.003 125.558 153.209 1.00 68.86  ? 292 PRO C CA  1 
ATOM 5777 C C   . PRO C 1 218 ? 121.682 124.807 153.193 1.00 66.84  ? 292 PRO C C   1 
ATOM 5778 O O   . PRO C 1 218 ? 121.052 124.603 154.236 1.00 69.00  ? 292 PRO C O   1 
ATOM 5779 C CB  . PRO C 1 218 ? 123.317 126.125 154.599 1.00 64.83  ? 292 PRO C CB  1 
ATOM 5780 C CG  . PRO C 1 218 ? 122.851 127.541 154.546 1.00 63.56  ? 292 PRO C CG  1 
ATOM 5781 C CD  . PRO C 1 218 ? 123.077 127.998 153.135 1.00 62.68  ? 292 PRO C CD  1 
ATOM 5782 N N   . SER C 1 219 ? 121.263 124.391 152.003 1.00 69.35  ? 293 SER C N   1 
ATOM 5783 C CA  . SER C 1 219 ? 120.031 123.640 151.809 1.00 74.29  ? 293 SER C CA  1 
ATOM 5784 C C   . SER C 1 219 ? 120.112 122.974 150.443 1.00 77.27  ? 293 SER C C   1 
ATOM 5785 O O   . SER C 1 219 ? 121.023 123.241 149.656 1.00 79.30  ? 293 SER C O   1 
ATOM 5786 C CB  . SER C 1 219 ? 118.802 124.545 151.930 1.00 75.22  ? 293 SER C CB  1 
ATOM 5787 O OG  . SER C 1 219 ? 118.850 125.600 150.986 1.00 70.55  ? 293 SER C OG  1 
ATOM 5788 N N   . SER C 1 220 ? 119.146 122.102 150.161 1.00 84.61  ? 294 SER C N   1 
ATOM 5789 C CA  . SER C 1 220 ? 119.154 121.358 148.904 1.00 86.13  ? 294 SER C CA  1 
ATOM 5790 C C   . SER C 1 220 ? 117.709 121.183 148.447 1.00 84.76  ? 294 SER C C   1 
ATOM 5791 O O   . SER C 1 220 ? 117.020 120.261 148.893 1.00 86.96  ? 294 SER C O   1 
ATOM 5792 C CB  . SER C 1 220 ? 119.856 120.016 149.064 1.00 86.30  ? 294 SER C CB  1 
ATOM 5793 O OG  . SER C 1 220 ? 121.227 120.197 149.373 1.00 87.65  ? 294 SER C OG  1 
ATOM 5794 N N   . TYR C 1 221 ? 117.270 122.065 147.559 1.00 77.81  ? 295 TYR C N   1 
ATOM 5795 C CA  . TYR C 1 221 ? 115.954 121.985 146.934 1.00 82.00  ? 295 TYR C CA  1 
ATOM 5796 C C   . TYR C 1 221 ? 115.966 122.952 145.755 1.00 82.56  ? 295 TYR C C   1 
ATOM 5797 O O   . TYR C 1 221 ? 116.850 123.807 145.641 1.00 80.26  ? 295 TYR C O   1 
ATOM 5798 C CB  . TYR C 1 221 ? 114.838 122.307 147.932 1.00 82.52  ? 295 TYR C CB  1 
ATOM 5799 C CG  . TYR C 1 221 ? 113.438 122.116 147.391 1.00 85.95  ? 295 TYR C CG  1 
ATOM 5800 C CD1 . TYR C 1 221 ? 112.902 120.845 147.233 1.00 87.36  ? 295 TYR C CD1 1 
ATOM 5801 C CD2 . TYR C 1 221 ? 112.652 123.206 147.041 1.00 86.74  ? 295 TYR C CD2 1 
ATOM 5802 C CE1 . TYR C 1 221 ? 111.623 120.665 146.741 1.00 91.03  ? 295 TYR C CE1 1 
ATOM 5803 C CE2 . TYR C 1 221 ? 111.373 123.036 146.548 1.00 88.62  ? 295 TYR C CE2 1 
ATOM 5804 C CZ  . TYR C 1 221 ? 110.863 121.764 146.400 1.00 91.65  ? 295 TYR C CZ  1 
ATOM 5805 O OH  . TYR C 1 221 ? 109.590 121.591 145.909 1.00 94.58  ? 295 TYR C OH  1 
ATOM 5806 N N   . LEU C 1 222 ? 114.978 122.812 144.876 1.00 80.24  ? 296 LEU C N   1 
ATOM 5807 C CA  . LEU C 1 222 ? 114.847 123.722 143.751 1.00 82.10  ? 296 LEU C CA  1 
ATOM 5808 C C   . LEU C 1 222 ? 114.513 125.124 144.257 1.00 83.58  ? 296 LEU C C   1 
ATOM 5809 O O   . LEU C 1 222 ? 114.210 125.337 145.434 1.00 87.05  ? 296 LEU C O   1 
ATOM 5810 C CB  . LEU C 1 222 ? 113.783 123.220 142.776 1.00 80.82  ? 296 LEU C CB  1 
ATOM 5811 C CG  . LEU C 1 222 ? 114.188 122.186 141.721 1.00 81.24  ? 296 LEU C CG  1 
ATOM 5812 C CD1 . LEU C 1 222 ? 115.224 122.770 140.773 1.00 81.47  ? 296 LEU C CD1 1 
ATOM 5813 C CD2 . LEU C 1 222 ? 114.691 120.889 142.345 1.00 80.19  ? 296 LEU C CD2 1 
ATOM 5814 N N   . SER C 1 223 ? 114.568 126.101 143.358 1.00 81.57  ? 297 SER C N   1 
ATOM 5815 C CA  . SER C 1 223 ? 114.287 127.480 143.720 1.00 81.78  ? 297 SER C CA  1 
ATOM 5816 C C   . SER C 1 223 ? 113.163 128.014 142.848 1.00 84.63  ? 297 SER C C   1 
ATOM 5817 O O   . SER C 1 223 ? 113.096 127.730 141.650 1.00 81.51  ? 297 SER C O   1 
ATOM 5818 C CB  . SER C 1 223 ? 115.531 128.366 143.579 1.00 81.02  ? 297 SER C CB  1 
ATOM 5819 O OG  . SER C 1 223 ? 116.573 127.918 144.427 1.00 79.92  ? 297 SER C OG  1 
ATOM 5820 N N   . ASN C 1 224 ? 112.273 128.790 143.466 1.00 77.64  ? 298 ASN C N   1 
ATOM 5821 C CA  . ASN C 1 224 ? 111.174 129.450 142.757 1.00 71.23  ? 298 ASN C CA  1 
ATOM 5822 C C   . ASN C 1 224 ? 111.196 130.918 143.177 1.00 72.81  ? 298 ASN C C   1 
ATOM 5823 O O   . ASN C 1 224 ? 110.543 131.309 144.147 1.00 74.78  ? 298 ASN C O   1 
ATOM 5824 C CB  . ASN C 1 224 ? 109.837 128.791 143.059 1.00 67.69  ? 298 ASN C CB  1 
ATOM 5825 C CG  . ASN C 1 224 ? 109.752 127.380 142.519 1.00 73.71  ? 298 ASN C CG  1 
ATOM 5826 O OD1 . ASN C 1 224 ? 109.323 127.161 141.386 1.00 73.23  ? 298 ASN C OD1 1 
ATOM 5827 N ND2 . ASN C 1 224 ? 110.162 126.411 143.329 1.00 74.78  ? 298 ASN C ND2 1 
ATOM 5828 N N   . VAL C 1 225 ? 111.953 131.723 142.437 1.00 62.68  ? 299 VAL C N   1 
ATOM 5829 C CA  . VAL C 1 225 ? 112.135 133.136 142.737 1.00 58.97  ? 299 VAL C CA  1 
ATOM 5830 C C   . VAL C 1 225 ? 111.734 133.947 141.512 1.00 59.94  ? 299 VAL C C   1 
ATOM 5831 O O   . VAL C 1 225 ? 112.021 133.558 140.374 1.00 57.69  ? 299 VAL C O   1 
ATOM 5832 C CB  . VAL C 1 225 ? 113.587 133.437 143.173 1.00 56.91  ? 299 VAL C CB  1 
ATOM 5833 C CG1 . VAL C 1 225 ? 114.565 133.168 142.050 1.00 62.31  ? 299 VAL C CG1 1 
ATOM 5834 C CG2 . VAL C 1 225 ? 113.714 134.860 143.670 1.00 57.77  ? 299 VAL C CG2 1 
ATOM 5835 N N   . ASP C 1 226 ? 111.041 135.057 141.745 1.00 65.48  ? 300 ASP C N   1 
ATOM 5836 C CA  . ASP C 1 226 ? 110.493 135.883 140.680 1.00 61.77  ? 300 ASP C CA  1 
ATOM 5837 C C   . ASP C 1 226 ? 111.427 137.043 140.367 1.00 63.68  ? 300 ASP C C   1 
ATOM 5838 O O   . ASP C 1 226 ? 111.985 137.669 141.273 1.00 71.47  ? 300 ASP C O   1 
ATOM 5839 C CB  . ASP C 1 226 ? 109.113 136.421 141.061 1.00 68.45  ? 300 ASP C CB  1 
ATOM 5840 C CG  . ASP C 1 226 ? 108.064 135.331 141.134 1.00 74.34  ? 300 ASP C CG  1 
ATOM 5841 O OD1 . ASP C 1 226 ? 108.389 134.170 140.808 1.00 72.79  ? 300 ASP C OD1 1 
ATOM 5842 O OD2 . ASP C 1 226 ? 106.914 135.634 141.516 1.00 74.40  ? 300 ASP C OD2 1 
ATOM 5843 N N   . VAL C 1 227 ? 111.592 137.323 139.078 1.00 55.35  ? 301 VAL C N   1 
ATOM 5844 C CA  . VAL C 1 227 ? 112.439 138.408 138.599 1.00 51.95  ? 301 VAL C CA  1 
ATOM 5845 C C   . VAL C 1 227 ? 111.537 139.486 138.019 1.00 55.57  ? 301 VAL C C   1 
ATOM 5846 O O   . VAL C 1 227 ? 110.863 139.263 137.005 1.00 67.16  ? 301 VAL C O   1 
ATOM 5847 C CB  . VAL C 1 227 ? 113.451 137.918 137.553 1.00 51.29  ? 301 VAL C CB  1 
ATOM 5848 C CG1 . VAL C 1 227 ? 114.253 139.085 137.010 1.00 51.12  ? 301 VAL C CG1 1 
ATOM 5849 C CG2 . VAL C 1 227 ? 114.366 136.866 138.151 1.00 56.80  ? 301 VAL C CG2 1 
ATOM 5850 N N   . TYR C 1 228 ? 111.527 140.651 138.655 1.00 56.90  ? 302 TYR C N   1 
ATOM 5851 C CA  . TYR C 1 228 ? 110.755 141.793 138.190 1.00 56.32  ? 302 TYR C CA  1 
ATOM 5852 C C   . TYR C 1 228 ? 111.671 142.763 137.459 1.00 59.38  ? 302 TYR C C   1 
ATOM 5853 O O   . TYR C 1 228 ? 112.804 143.006 137.884 1.00 63.40  ? 302 TYR C O   1 
ATOM 5854 C CB  . TYR C 1 228 ? 110.068 142.513 139.352 1.00 59.67  ? 302 TYR C CB  1 
ATOM 5855 C CG  . TYR C 1 228 ? 108.959 141.731 140.013 1.00 62.58  ? 302 TYR C CG  1 
ATOM 5856 C CD1 . TYR C 1 228 ? 109.233 140.613 140.787 1.00 61.76  ? 302 TYR C CD1 1 
ATOM 5857 C CD2 . TYR C 1 228 ? 107.637 142.124 139.879 1.00 67.13  ? 302 TYR C CD2 1 
ATOM 5858 C CE1 . TYR C 1 228 ? 108.221 139.902 141.396 1.00 58.07  ? 302 TYR C CE1 1 
ATOM 5859 C CE2 . TYR C 1 228 ? 106.620 141.422 140.487 1.00 66.88  ? 302 TYR C CE2 1 
ATOM 5860 C CZ  . TYR C 1 228 ? 106.917 140.310 141.242 1.00 61.62  ? 302 TYR C CZ  1 
ATOM 5861 O OH  . TYR C 1 228 ? 105.903 139.605 141.849 1.00 64.38  ? 302 TYR C OH  1 
ATOM 5862 N N   . LEU C 1 229 ? 111.174 143.314 136.356 1.00 56.00  ? 303 LEU C N   1 
ATOM 5863 C CA  . LEU C 1 229 ? 111.915 144.280 135.551 1.00 56.64  ? 303 LEU C CA  1 
ATOM 5864 C C   . LEU C 1 229 ? 110.980 145.458 135.293 1.00 57.88  ? 303 LEU C C   1 
ATOM 5865 O O   . LEU C 1 229 ? 110.083 145.370 134.450 1.00 59.81  ? 303 LEU C O   1 
ATOM 5866 C CB  . LEU C 1 229 ? 112.410 143.643 134.256 1.00 56.91  ? 303 LEU C CB  1 
ATOM 5867 C CG  . LEU C 1 229 ? 113.412 144.405 133.390 1.00 56.31  ? 303 LEU C CG  1 
ATOM 5868 C CD1 . LEU C 1 229 ? 114.289 143.434 132.627 1.00 58.97  ? 303 LEU C CD1 1 
ATOM 5869 C CD2 . LEU C 1 229 ? 112.689 145.314 132.429 1.00 52.77  ? 303 LEU C CD2 1 
ATOM 5870 N N   . ASP C 1 230 ? 111.195 146.553 136.023 1.00 65.48  ? 304 ASP C N   1 
ATOM 5871 C CA  . ASP C 1 230 ? 110.329 147.732 135.969 1.00 64.49  ? 304 ASP C CA  1 
ATOM 5872 C C   . ASP C 1 230 ? 108.880 147.377 136.300 1.00 64.94  ? 304 ASP C C   1 
ATOM 5873 O O   . ASP C 1 230 ? 107.941 147.877 135.677 1.00 66.47  ? 304 ASP C O   1 
ATOM 5874 C CB  . ASP C 1 230 ? 110.420 148.427 134.610 1.00 65.71  ? 304 ASP C CB  1 
ATOM 5875 C CG  . ASP C 1 230 ? 111.813 148.940 134.310 1.00 69.79  ? 304 ASP C CG  1 
ATOM 5876 O OD1 . ASP C 1 230 ? 112.573 149.193 135.268 1.00 71.92  ? 304 ASP C OD1 1 
ATOM 5877 O OD2 . ASP C 1 230 ? 112.146 149.093 133.117 1.00 68.22  ? 304 ASP C OD2 1 
ATOM 5878 N N   . GLY C 1 231 ? 108.695 146.507 137.290 1.00 70.89  ? 305 GLY C N   1 
ATOM 5879 C CA  . GLY C 1 231 ? 107.360 146.117 137.700 1.00 71.89  ? 305 GLY C CA  1 
ATOM 5880 C C   . GLY C 1 231 ? 106.609 145.284 136.692 1.00 71.58  ? 305 GLY C C   1 
ATOM 5881 O O   . GLY C 1 231 ? 105.379 145.213 136.750 1.00 77.55  ? 305 GLY C O   1 
ATOM 5882 N N   . HIS C 1 232 ? 107.317 144.644 135.770 1.00 68.61  ? 306 HIS C N   1 
ATOM 5883 C CA  . HIS C 1 232 ? 106.745 143.878 134.668 1.00 72.64  ? 306 HIS C CA  1 
ATOM 5884 C C   . HIS C 1 232 ? 107.334 142.479 134.644 1.00 73.11  ? 306 HIS C C   1 
ATOM 5885 O O   . HIS C 1 232 ? 107.903 142.046 133.640 1.00 79.13  ? 306 HIS C O   1 
ATOM 5886 C CB  . HIS C 1 232 ? 106.954 144.578 133.328 1.00 73.77  ? 306 HIS C CB  1 
ATOM 5887 C CG  . HIS C 1 232 ? 106.187 145.855 133.190 1.00 75.89  ? 306 HIS C CG  1 
ATOM 5888 N ND1 . HIS C 1 232 ? 106.512 146.824 132.266 1.00 76.45  ? 306 HIS C ND1 1 
ATOM 5889 C CD2 . HIS C 1 232 ? 105.104 146.320 133.856 1.00 75.07  ? 306 HIS C CD2 1 
ATOM 5890 C CE1 . HIS C 1 232 ? 105.665 147.831 132.371 1.00 76.74  ? 306 HIS C CE1 1 
ATOM 5891 N NE2 . HIS C 1 232 ? 104.800 147.551 133.329 1.00 79.08  ? 306 HIS C NE2 1 
ATOM 5892 N N   . LEU C 1 233 ? 107.235 141.783 135.781 1.00 55.35  ? 307 LEU C N   1 
ATOM 5893 C CA  . LEU C 1 233 ? 107.938 140.528 136.036 1.00 57.02  ? 307 LEU C CA  1 
ATOM 5894 C C   . LEU C 1 233 ? 108.041 139.677 134.780 1.00 62.55  ? 307 LEU C C   1 
ATOM 5895 O O   . LEU C 1 233 ? 107.050 139.438 134.087 1.00 68.87  ? 307 LEU C O   1 
ATOM 5896 C CB  . LEU C 1 233 ? 107.232 139.746 137.153 1.00 59.91  ? 307 LEU C CB  1 
ATOM 5897 C CG  . LEU C 1 233 ? 105.796 139.221 137.014 1.00 65.45  ? 307 LEU C CG  1 
ATOM 5898 C CD1 . LEU C 1 233 ? 105.752 137.843 136.360 1.00 64.48  ? 307 LEU C CD1 1 
ATOM 5899 C CD2 . LEU C 1 233 ? 105.088 139.186 138.360 1.00 63.53  ? 307 LEU C CD2 1 
ATOM 5900 N N   . ILE C 1 234 ? 109.260 139.254 134.476 1.00 57.79  ? 308 ILE C N   1 
ATOM 5901 C CA  . ILE C 1 234 ? 109.586 138.680 133.184 1.00 65.47  ? 308 ILE C CA  1 
ATOM 5902 C C   . ILE C 1 234 ? 109.616 137.161 133.235 1.00 69.08  ? 308 ILE C C   1 
ATOM 5903 O O   . ILE C 1 234 ? 109.103 136.494 132.337 1.00 76.56  ? 308 ILE C O   1 
ATOM 5904 C CB  . ILE C 1 234 ? 110.923 139.261 132.676 1.00 65.64  ? 308 ILE C CB  1 
ATOM 5905 C CG1 . ILE C 1 234 ? 111.995 139.174 133.762 1.00 64.45  ? 308 ILE C CG1 1 
ATOM 5906 C CG2 . ILE C 1 234 ? 110.736 140.708 132.266 1.00 65.58  ? 308 ILE C CG2 1 
ATOM 5907 C CD1 . ILE C 1 234 ? 113.330 139.754 133.353 1.00 65.38  ? 308 ILE C CD1 1 
ATOM 5908 N N   . THR C 1 235 ? 110.206 136.593 134.282 1.00 56.68  ? 309 THR C N   1 
ATOM 5909 C CA  . THR C 1 235 ? 110.281 135.146 134.389 1.00 64.16  ? 309 THR C CA  1 
ATOM 5910 C C   . THR C 1 235 ? 110.441 134.758 135.848 1.00 66.96  ? 309 THR C C   1 
ATOM 5911 O O   . THR C 1 235 ? 110.912 135.543 136.675 1.00 73.42  ? 309 THR C O   1 
ATOM 5912 C CB  . THR C 1 235 ? 111.433 134.574 133.553 1.00 69.42  ? 309 THR C CB  1 
ATOM 5913 O OG1 . THR C 1 235 ? 111.302 133.150 133.464 1.00 73.35  ? 309 THR C OG1 1 
ATOM 5914 C CG2 . THR C 1 235 ? 112.776 134.919 134.180 1.00 68.33  ? 309 THR C CG2 1 
ATOM 5915 N N   . THR C 1 236 ? 110.021 133.535 136.150 1.00 66.53  ? 310 THR C N   1 
ATOM 5916 C CA  . THR C 1 236 ? 110.280 132.894 137.432 1.00 68.16  ? 310 THR C CA  1 
ATOM 5917 C C   . THR C 1 236 ? 111.325 131.819 137.176 1.00 69.89  ? 310 THR C C   1 
ATOM 5918 O O   . THR C 1 236 ? 111.007 130.751 136.644 1.00 66.51  ? 310 THR C O   1 
ATOM 5919 C CB  . THR C 1 236 ? 109.005 132.301 138.026 1.00 70.00  ? 310 THR C CB  1 
ATOM 5920 O OG1 . THR C 1 236 ? 108.112 133.359 138.398 1.00 73.27  ? 310 THR C OG1 1 
ATOM 5921 C CG2 . THR C 1 236 ? 109.327 131.465 139.257 1.00 70.05  ? 310 THR C CG2 1 
ATOM 5922 N N   . VAL C 1 237 ? 112.570 132.106 137.535 1.00 74.82  ? 311 VAL C N   1 
ATOM 5923 C CA  . VAL C 1 237 ? 113.665 131.190 137.245 1.00 73.54  ? 311 VAL C CA  1 
ATOM 5924 C C   . VAL C 1 237 ? 113.625 130.034 138.235 1.00 72.67  ? 311 VAL C C   1 
ATOM 5925 O O   . VAL C 1 237 ? 113.569 130.235 139.454 1.00 74.48  ? 311 VAL C O   1 
ATOM 5926 C CB  . VAL C 1 237 ? 115.017 131.925 137.262 1.00 74.91  ? 311 VAL C CB  1 
ATOM 5927 C CG1 . VAL C 1 237 ? 115.326 132.500 138.632 1.00 71.70  ? 311 VAL C CG1 1 
ATOM 5928 C CG2 . VAL C 1 237 ? 116.131 130.990 136.811 1.00 72.79  ? 311 VAL C CG2 1 
ATOM 5929 N N   . GLN C 1 238 ? 113.610 128.816 137.706 1.00 69.76  ? 312 GLN C N   1 
ATOM 5930 C CA  . GLN C 1 238 ? 113.545 127.606 138.510 1.00 69.87  ? 312 GLN C CA  1 
ATOM 5931 C C   . GLN C 1 238 ? 114.776 126.765 138.219 1.00 70.44  ? 312 GLN C C   1 
ATOM 5932 O O   . GLN C 1 238 ? 115.055 126.442 137.060 1.00 73.13  ? 312 GLN C O   1 
ATOM 5933 C CB  . GLN C 1 238 ? 112.266 126.821 138.218 1.00 72.49  ? 312 GLN C CB  1 
ATOM 5934 C CG  . GLN C 1 238 ? 112.115 125.548 139.030 1.00 73.88  ? 312 GLN C CG  1 
ATOM 5935 C CD  . GLN C 1 238 ? 110.833 124.807 138.711 1.00 77.48  ? 312 GLN C CD  1 
ATOM 5936 O OE1 . GLN C 1 238 ? 110.025 125.261 137.901 1.00 77.19  ? 312 GLN C OE1 1 
ATOM 5937 N NE2 . GLN C 1 238 ? 110.639 123.659 139.349 1.00 74.74  ? 312 GLN C NE2 1 
ATOM 5938 N N   . GLY C 1 239 ? 115.499 126.417 139.261 1.00 60.22  ? 313 GLY C N   1 
ATOM 5939 C CA  . GLY C 1 239 ? 116.770 125.747 139.134 1.00 60.76  ? 313 GLY C CA  1 
ATOM 5940 C C   . GLY C 1 239 ? 117.673 126.142 140.289 1.00 61.47  ? 313 GLY C C   1 
ATOM 5941 O O   . GLY C 1 239 ? 117.211 126.323 141.413 1.00 65.37  ? 313 GLY C O   1 
ATOM 5942 N N   . ASP C 1 240 ? 118.965 126.263 139.987 1.00 53.88  ? 314 ASP C N   1 
ATOM 5943 C CA  . ASP C 1 240 ? 119.920 126.617 141.029 1.00 57.04  ? 314 ASP C CA  1 
ATOM 5944 C C   . ASP C 1 240 ? 119.834 128.096 141.393 1.00 56.06  ? 314 ASP C C   1 
ATOM 5945 O O   . ASP C 1 240 ? 119.832 128.443 142.579 1.00 65.34  ? 314 ASP C O   1 
ATOM 5946 C CB  . ASP C 1 240 ? 121.333 126.247 140.595 1.00 60.09  ? 314 ASP C CB  1 
ATOM 5947 C CG  . ASP C 1 240 ? 121.521 124.753 140.440 1.00 64.62  ? 314 ASP C CG  1 
ATOM 5948 O OD1 . ASP C 1 240 ? 120.741 123.989 141.045 1.00 65.27  ? 314 ASP C OD1 1 
ATOM 5949 O OD2 . ASP C 1 240 ? 122.449 124.341 139.713 1.00 64.07  ? 314 ASP C OD2 1 
ATOM 5950 N N   . GLY C 1 241 ? 119.757 128.979 140.404 1.00 40.30  ? 315 GLY C N   1 
ATOM 5951 C CA  . GLY C 1 241 ? 119.671 130.398 140.705 1.00 42.93  ? 315 GLY C CA  1 
ATOM 5952 C C   . GLY C 1 241 ? 119.933 131.254 139.476 1.00 39.56  ? 315 GLY C C   1 
ATOM 5953 O O   . GLY C 1 241 ? 119.748 130.814 138.345 1.00 38.30  ? 315 GLY C O   1 
ATOM 5954 N N   . VAL C 1 242 ? 120.365 132.490 139.740 1.00 34.85  ? 316 VAL C N   1 
ATOM 5955 C CA  . VAL C 1 242 ? 120.573 133.507 138.715 1.00 30.79  ? 316 VAL C CA  1 
ATOM 5956 C C   . VAL C 1 242 ? 121.842 134.292 139.041 1.00 40.96  ? 316 VAL C C   1 
ATOM 5957 O O   . VAL C 1 242 ? 122.193 134.483 140.209 1.00 44.80  ? 316 VAL C O   1 
ATOM 5958 C CB  . VAL C 1 242 ? 119.341 134.436 138.600 1.00 29.50  ? 316 VAL C CB  1 
ATOM 5959 C CG1 . VAL C 1 242 ? 119.087 135.156 139.913 1.00 36.67  ? 316 VAL C CG1 1 
ATOM 5960 C CG2 . VAL C 1 242 ? 119.503 135.425 137.457 1.00 43.18  ? 316 VAL C CG2 1 
ATOM 5961 N N   . ILE C 1 243 ? 122.536 134.747 137.993 1.00 37.99  ? 317 ILE C N   1 
ATOM 5962 C CA  . ILE C 1 243 ? 123.864 135.348 138.109 1.00 27.92  ? 317 ILE C CA  1 
ATOM 5963 C C   . ILE C 1 243 ? 123.842 136.769 137.550 1.00 32.30  ? 317 ILE C C   1 
ATOM 5964 O O   . ILE C 1 243 ? 124.716 137.143 136.761 1.00 51.36  ? 317 ILE C O   1 
ATOM 5965 C CB  . ILE C 1 243 ? 124.948 134.505 137.408 1.00 33.74  ? 317 ILE C CB  1 
ATOM 5966 C CG1 . ILE C 1 243 ? 124.971 133.088 137.940 1.00 40.43  ? 317 ILE C CG1 1 
ATOM 5967 C CG2 . ILE C 1 243 ? 126.344 135.008 137.749 1.00 41.15  ? 317 ILE C CG2 1 
ATOM 5968 C CD1 . ILE C 1 243 ? 125.867 132.183 137.126 1.00 42.84  ? 317 ILE C CD1 1 
ATOM 5969 N N   . VAL C 1 244 ? 122.790 137.532 137.849 1.00 21.48  ? 318 VAL C N   1 
ATOM 5970 C CA  . VAL C 1 244 ? 122.696 138.916 137.383 1.00 23.39  ? 318 VAL C CA  1 
ATOM 5971 C C   . VAL C 1 244 ? 124.029 139.623 137.596 1.00 31.24  ? 318 VAL C C   1 
ATOM 5972 O O   . VAL C 1 244 ? 124.541 139.681 138.720 1.00 43.93  ? 318 VAL C O   1 
ATOM 5973 C CB  . VAL C 1 244 ? 121.564 139.671 138.099 1.00 28.31  ? 318 VAL C CB  1 
ATOM 5974 C CG1 . VAL C 1 244 ? 121.654 141.152 137.795 1.00 34.24  ? 318 VAL C CG1 1 
ATOM 5975 C CG2 . VAL C 1 244 ? 120.213 139.118 137.684 1.00 38.91  ? 318 VAL C CG2 1 
ATOM 5976 N N   . SER C 1 245 ? 124.598 140.165 136.519 1.00 37.83  ? 319 SER C N   1 
ATOM 5977 C CA  . SER C 1 245 ? 126.001 140.552 136.515 1.00 27.70  ? 319 SER C CA  1 
ATOM 5978 C C   . SER C 1 245 ? 126.238 141.684 135.525 1.00 39.82  ? 319 SER C C   1 
ATOM 5979 O O   . SER C 1 245 ? 125.416 141.959 134.648 1.00 50.35  ? 319 SER C O   1 
ATOM 5980 C CB  . SER C 1 245 ? 126.896 139.363 136.165 1.00 36.86  ? 319 SER C CB  1 
ATOM 5981 O OG  . SER C 1 245 ? 126.569 138.849 134.888 1.00 34.47  ? 319 SER C OG  1 
ATOM 5982 N N   . THR C 1 246 ? 127.384 142.337 135.684 1.00 48.03  ? 320 THR C N   1 
ATOM 5983 C CA  . THR C 1 246 ? 127.837 143.384 134.781 1.00 41.48  ? 320 THR C CA  1 
ATOM 5984 C C   . THR C 1 246 ? 128.609 142.773 133.618 1.00 50.13  ? 320 THR C C   1 
ATOM 5985 O O   . THR C 1 246 ? 128.936 141.585 133.630 1.00 57.38  ? 320 THR C O   1 
ATOM 5986 C CB  . THR C 1 246 ? 128.714 144.376 135.541 1.00 40.19  ? 320 THR C CB  1 
ATOM 5987 O OG1 . THR C 1 246 ? 129.916 143.722 135.962 1.00 48.91  ? 320 THR C OG1 1 
ATOM 5988 C CG2 . THR C 1 246 ? 127.991 144.906 136.755 1.00 50.64  ? 320 THR C CG2 1 
ATOM 5989 N N   . PRO C 1 247 ? 128.908 143.563 132.580 1.00 45.37  ? 321 PRO C N   1 
ATOM 5990 C CA  . PRO C 1 247 ? 129.783 143.052 131.515 1.00 38.77  ? 321 PRO C CA  1 
ATOM 5991 C C   . PRO C 1 247 ? 131.146 142.616 132.013 1.00 50.67  ? 321 PRO C C   1 
ATOM 5992 O O   . PRO C 1 247 ? 131.736 141.689 131.445 1.00 51.00  ? 321 PRO C O   1 
ATOM 5993 C CB  . PRO C 1 247 ? 129.889 144.243 130.557 1.00 44.57  ? 321 PRO C CB  1 
ATOM 5994 C CG  . PRO C 1 247 ? 128.626 144.970 130.746 1.00 51.83  ? 321 PRO C CG  1 
ATOM 5995 C CD  . PRO C 1 247 ? 128.288 144.844 132.202 1.00 51.67  ? 321 PRO C CD  1 
ATOM 5996 N N   . THR C 1 248 ? 131.671 143.261 133.057 1.00 57.78  ? 322 THR C N   1 
ATOM 5997 C CA  . THR C 1 248 ? 132.950 142.853 133.623 1.00 50.67  ? 322 THR C CA  1 
ATOM 5998 C C   . THR C 1 248 ? 132.891 141.458 134.226 1.00 52.82  ? 322 THR C C   1 
ATOM 5999 O O   . THR C 1 248 ? 133.923 140.783 134.296 1.00 57.12  ? 322 THR C O   1 
ATOM 6000 C CB  . THR C 1 248 ? 133.393 143.850 134.690 1.00 46.33  ? 322 THR C CB  1 
ATOM 6001 O OG1 . THR C 1 248 ? 132.715 143.563 135.919 1.00 56.89  ? 322 THR C OG1 1 
ATOM 6002 C CG2 . THR C 1 248 ? 133.037 145.255 134.263 1.00 52.37  ? 322 THR C CG2 1 
ATOM 6003 N N   . GLY C 1 249 ? 131.716 141.017 134.663 1.00 46.39  ? 323 GLY C N   1 
ATOM 6004 C CA  . GLY C 1 249 ? 131.517 139.683 135.179 1.00 43.53  ? 323 GLY C CA  1 
ATOM 6005 C C   . GLY C 1 249 ? 131.147 138.651 134.144 1.00 51.50  ? 323 GLY C C   1 
ATOM 6006 O O   . GLY C 1 249 ? 130.940 137.487 134.499 1.00 55.42  ? 323 GLY C O   1 
ATOM 6007 N N   . SER C 1 250 ? 131.054 139.037 132.870 1.00 57.67  ? 324 SER C N   1 
ATOM 6008 C CA  . SER C 1 250 ? 130.764 138.086 131.805 1.00 57.60  ? 324 SER C CA  1 
ATOM 6009 C C   . SER C 1 250 ? 131.909 137.115 131.562 1.00 61.20  ? 324 SER C C   1 
ATOM 6010 O O   . SER C 1 250 ? 131.724 136.134 130.836 1.00 64.18  ? 324 SER C O   1 
ATOM 6011 C CB  . SER C 1 250 ? 130.437 138.831 130.511 1.00 59.93  ? 324 SER C CB  1 
ATOM 6012 O OG  . SER C 1 250 ? 131.510 139.669 130.122 1.00 62.59  ? 324 SER C OG  1 
ATOM 6013 N N   . THR C 1 251 ? 133.080 137.373 132.138 1.00 58.26  ? 325 THR C N   1 
ATOM 6014 C CA  . THR C 1 251 ? 134.224 136.471 132.090 1.00 60.19  ? 325 THR C CA  1 
ATOM 6015 C C   . THR C 1 251 ? 134.484 135.871 133.468 1.00 61.28  ? 325 THR C C   1 
ATOM 6016 O O   . THR C 1 251 ? 135.627 135.717 133.900 1.00 64.32  ? 325 THR C O   1 
ATOM 6017 C CB  . THR C 1 251 ? 135.461 137.196 131.571 1.00 65.95  ? 325 THR C CB  1 
ATOM 6018 O OG1 . THR C 1 251 ? 135.812 138.251 132.474 1.00 63.15  ? 325 THR C OG1 1 
ATOM 6019 C CG2 . THR C 1 251 ? 135.187 137.786 130.196 1.00 61.90  ? 325 THR C CG2 1 
ATOM 6020 N N   . ALA C 1 252 ? 133.407 135.532 134.166 1.00 56.67  ? 326 ALA C N   1 
ATOM 6021 C CA  . ALA C 1 252 ? 133.453 135.082 135.551 1.00 56.89  ? 326 ALA C CA  1 
ATOM 6022 C C   . ALA C 1 252 ? 132.439 133.952 135.692 1.00 55.56  ? 326 ALA C C   1 
ATOM 6023 O O   . ALA C 1 252 ? 132.043 133.324 134.705 1.00 57.83  ? 326 ALA C O   1 
ATOM 6024 C CB  . ALA C 1 252 ? 133.200 136.250 136.515 1.00 53.60  ? 326 ALA C CB  1 
ATOM 6025 N N   . TYR C 1 253 ? 132.042 133.661 136.935 1.00 45.79  ? 327 TYR C N   1 
ATOM 6026 C CA  . TYR C 1 253 ? 131.059 132.611 137.196 1.00 44.32  ? 327 TYR C CA  1 
ATOM 6027 C C   . TYR C 1 253 ? 129.824 132.731 136.309 1.00 49.01  ? 327 TYR C C   1 
ATOM 6028 O O   . TYR C 1 253 ? 129.141 131.730 136.061 1.00 57.91  ? 327 TYR C O   1 
ATOM 6029 C CB  . TYR C 1 253 ? 130.653 132.640 138.670 1.00 50.00  ? 327 TYR C CB  1 
ATOM 6030 C CG  . TYR C 1 253 ? 129.667 131.569 139.065 1.00 50.98  ? 327 TYR C CG  1 
ATOM 6031 C CD1 . TYR C 1 253 ? 129.917 130.232 138.791 1.00 54.25  ? 327 TYR C CD1 1 
ATOM 6032 C CD2 . TYR C 1 253 ? 128.493 131.892 139.725 1.00 46.10  ? 327 TYR C CD2 1 
ATOM 6033 C CE1 . TYR C 1 253 ? 129.019 129.250 139.155 1.00 50.07  ? 327 TYR C CE1 1 
ATOM 6034 C CE2 . TYR C 1 253 ? 127.592 130.919 140.094 1.00 46.29  ? 327 TYR C CE2 1 
ATOM 6035 C CZ  . TYR C 1 253 ? 127.859 129.600 139.807 1.00 49.21  ? 327 TYR C CZ  1 
ATOM 6036 O OH  . TYR C 1 253 ? 126.959 128.628 140.174 1.00 56.35  ? 327 TYR C OH  1 
ATOM 6037 N N   . ALA C 1 254 ? 129.518 133.935 135.823 1.00 47.36  ? 328 ALA C N   1 
ATOM 6038 C CA  . ALA C 1 254 ? 128.442 134.083 134.849 1.00 43.81  ? 328 ALA C CA  1 
ATOM 6039 C C   . ALA C 1 254 ? 128.759 133.330 133.565 1.00 37.44  ? 328 ALA C C   1 
ATOM 6040 O O   . ALA C 1 254 ? 127.869 132.726 132.955 1.00 42.00  ? 328 ALA C O   1 
ATOM 6041 C CB  . ALA C 1 254 ? 128.196 135.562 134.556 1.00 41.13  ? 328 ALA C CB  1 
ATOM 6042 N N   . ALA C 1 255 ? 130.024 133.355 133.138 1.00 43.79  ? 329 ALA C N   1 
ATOM 6043 C CA  . ALA C 1 255 ? 130.415 132.641 131.927 1.00 41.30  ? 329 ALA C CA  1 
ATOM 6044 C C   . ALA C 1 255 ? 130.309 131.134 132.100 1.00 45.66  ? 329 ALA C C   1 
ATOM 6045 O O   . ALA C 1 255 ? 129.990 130.424 131.139 1.00 56.16  ? 329 ALA C O   1 
ATOM 6046 C CB  . ALA C 1 255 ? 131.837 133.023 131.522 1.00 45.45  ? 329 ALA C CB  1 
ATOM 6047 N N   . ALA C 1 256 ? 130.574 130.626 133.303 1.00 38.55  ? 330 ALA C N   1 
ATOM 6048 C CA  . ALA C 1 256 ? 130.468 129.195 133.550 1.00 40.60  ? 330 ALA C CA  1 
ATOM 6049 C C   . ALA C 1 256 ? 129.043 128.680 133.422 1.00 49.76  ? 330 ALA C C   1 
ATOM 6050 O O   . ALA C 1 256 ? 128.851 127.464 133.318 1.00 52.66  ? 330 ALA C O   1 
ATOM 6051 C CB  . ALA C 1 256 ? 131.016 128.861 134.937 1.00 37.50  ? 330 ALA C CB  1 
ATOM 6052 N N   . ALA C 1 257 ? 128.048 129.564 133.425 1.00 54.21  ? 331 ALA C N   1 
ATOM 6053 C CA  . ALA C 1 257 ? 126.652 129.182 133.290 1.00 43.85  ? 331 ALA C CA  1 
ATOM 6054 C C   . ALA C 1 257 ? 126.156 129.266 131.853 1.00 44.41  ? 331 ALA C C   1 
ATOM 6055 O O   . ALA C 1 257 ? 124.960 129.080 131.609 1.00 53.17  ? 331 ALA C O   1 
ATOM 6056 C CB  . ALA C 1 257 ? 125.782 130.050 134.198 1.00 43.22  ? 331 ALA C CB  1 
ATOM 6057 N N   . GLY C 1 258 ? 127.043 129.535 130.900 1.00 46.36  ? 332 GLY C N   1 
ATOM 6058 C CA  . GLY C 1 258 ? 126.671 129.623 129.505 1.00 50.97  ? 332 GLY C CA  1 
ATOM 6059 C C   . GLY C 1 258 ? 126.445 131.018 128.971 1.00 48.13  ? 332 GLY C C   1 
ATOM 6060 O O   . GLY C 1 258 ? 125.928 131.156 127.857 1.00 48.87  ? 332 GLY C O   1 
ATOM 6061 N N   . ALA C 1 259 ? 126.812 132.051 129.720 1.00 50.09  ? 333 ALA C N   1 
ATOM 6062 C CA  . ALA C 1 259 ? 126.596 133.420 129.281 1.00 49.13  ? 333 ALA C CA  1 
ATOM 6063 C C   . ALA C 1 259 ? 127.598 133.816 128.207 1.00 49.06  ? 333 ALA C C   1 
ATOM 6064 O O   . ALA C 1 259 ? 128.772 133.440 128.250 1.00 56.12  ? 333 ALA C O   1 
ATOM 6065 C CB  . ALA C 1 259 ? 126.697 134.386 130.461 1.00 51.15  ? 333 ALA C CB  1 
ATOM 6066 N N   . SER C 1 260 ? 127.118 134.583 127.232 1.00 49.85  ? 334 SER C N   1 
ATOM 6067 C CA  . SER C 1 260 ? 127.998 135.146 126.224 1.00 49.25  ? 334 SER C CA  1 
ATOM 6068 C C   . SER C 1 260 ? 128.910 136.195 126.851 1.00 53.21  ? 334 SER C C   1 
ATOM 6069 O O   . SER C 1 260 ? 128.562 136.854 127.834 1.00 59.69  ? 334 SER C O   1 
ATOM 6070 C CB  . SER C 1 260 ? 127.187 135.761 125.085 1.00 52.28  ? 334 SER C CB  1 
ATOM 6071 O OG  . SER C 1 260 ? 126.330 136.783 125.564 1.00 62.31  ? 334 SER C OG  1 
ATOM 6072 N N   . MET C 1 261 ? 130.092 136.348 126.267 1.00 48.69  ? 335 MET C N   1 
ATOM 6073 C CA  . MET C 1 261 ? 131.138 137.195 126.826 1.00 45.86  ? 335 MET C CA  1 
ATOM 6074 C C   . MET C 1 261 ? 130.990 138.603 126.261 1.00 42.82  ? 335 MET C C   1 
ATOM 6075 O O   . MET C 1 261 ? 131.123 138.814 125.052 1.00 58.84  ? 335 MET C O   1 
ATOM 6076 C CB  . MET C 1 261 ? 132.514 136.605 126.531 1.00 53.01  ? 335 MET C CB  1 
ATOM 6077 C CG  . MET C 1 261 ? 132.687 135.208 127.109 1.00 53.40  ? 335 MET C CG  1 
ATOM 6078 S SD  . MET C 1 261 ? 134.316 134.496 126.841 1.00 70.57  ? 335 MET C SD  1 
ATOM 6079 C CE  . MET C 1 261 ? 134.465 134.669 125.069 1.00 57.20  ? 335 MET C CE  1 
ATOM 6080 N N   . ILE C 1 262 ? 130.715 139.559 127.141 1.00 33.80  ? 336 ILE C N   1 
ATOM 6081 C CA  . ILE C 1 262 ? 130.415 140.929 126.749 1.00 41.04  ? 336 ILE C CA  1 
ATOM 6082 C C   . ILE C 1 262 ? 131.644 141.797 126.981 1.00 47.23  ? 336 ILE C C   1 
ATOM 6083 O O   . ILE C 1 262 ? 132.277 141.723 128.041 1.00 58.06  ? 336 ILE C O   1 
ATOM 6084 C CB  . ILE C 1 262 ? 129.208 141.470 127.533 1.00 51.78  ? 336 ILE C CB  1 
ATOM 6085 C CG1 . ILE C 1 262 ? 127.968 140.618 127.264 1.00 53.82  ? 336 ILE C CG1 1 
ATOM 6086 C CG2 . ILE C 1 262 ? 128.949 142.924 127.183 1.00 54.74  ? 336 ILE C CG2 1 
ATOM 6087 C CD1 . ILE C 1 262 ? 126.682 141.232 127.768 1.00 53.37  ? 336 ILE C CD1 1 
ATOM 6088 N N   . HIS C 1 263 ? 131.985 142.613 125.991 1.00 47.22  ? 337 HIS C N   1 
ATOM 6089 C CA  . HIS C 1 263 ? 133.072 143.565 126.155 1.00 47.40  ? 337 HIS C CA  1 
ATOM 6090 C C   . HIS C 1 263 ? 132.681 144.621 127.186 1.00 52.03  ? 337 HIS C C   1 
ATOM 6091 O O   . HIS C 1 263 ? 131.529 145.068 127.209 1.00 59.10  ? 337 HIS C O   1 
ATOM 6092 C CB  . HIS C 1 263 ? 133.407 144.225 124.818 1.00 50.10  ? 337 HIS C CB  1 
ATOM 6093 C CG  . HIS C 1 263 ? 134.637 145.076 124.854 1.00 54.20  ? 337 HIS C CG  1 
ATOM 6094 N ND1 . HIS C 1 263 ? 134.625 146.383 125.290 1.00 56.13  ? 337 HIS C ND1 1 
ATOM 6095 C CD2 . HIS C 1 263 ? 135.916 144.809 124.503 1.00 57.69  ? 337 HIS C CD2 1 
ATOM 6096 C CE1 . HIS C 1 263 ? 135.844 146.884 125.209 1.00 53.05  ? 337 HIS C CE1 1 
ATOM 6097 N NE2 . HIS C 1 263 ? 136.647 145.949 124.736 1.00 55.76  ? 337 HIS C NE2 1 
ATOM 6098 N N   . PRO C 1 264 ? 133.609 145.048 128.049 1.00 48.02  ? 338 PRO C N   1 
ATOM 6099 C CA  . PRO C 1 264 ? 133.243 145.955 129.146 1.00 47.74  ? 338 PRO C CA  1 
ATOM 6100 C C   . PRO C 1 264 ? 132.873 147.366 128.715 1.00 49.30  ? 338 PRO C C   1 
ATOM 6101 O O   . PRO C 1 264 ? 132.624 148.207 129.586 1.00 52.69  ? 338 PRO C O   1 
ATOM 6102 C CB  . PRO C 1 264 ? 134.502 145.961 130.024 1.00 51.19  ? 338 PRO C CB  1 
ATOM 6103 C CG  . PRO C 1 264 ? 135.599 145.560 129.122 1.00 51.37  ? 338 PRO C CG  1 
ATOM 6104 C CD  . PRO C 1 264 ? 135.001 144.586 128.161 1.00 50.05  ? 338 PRO C CD  1 
ATOM 6105 N N   . ASN C 1 265 ? 132.824 147.668 127.421 1.00 59.11  ? 339 ASN C N   1 
ATOM 6106 C CA  . ASN C 1 265 ? 132.336 148.960 126.957 1.00 59.58  ? 339 ASN C CA  1 
ATOM 6107 C C   . ASN C 1 265 ? 130.892 148.909 126.476 1.00 55.99  ? 339 ASN C C   1 
ATOM 6108 O O   . ASN C 1 265 ? 130.398 149.906 125.941 1.00 59.86  ? 339 ASN C O   1 
ATOM 6109 C CB  . ASN C 1 265 ? 133.232 149.501 125.840 1.00 58.43  ? 339 ASN C CB  1 
ATOM 6110 C CG  . ASN C 1 265 ? 134.520 150.099 126.364 1.00 63.99  ? 339 ASN C CG  1 
ATOM 6111 O OD1 . ASN C 1 265 ? 134.580 150.573 127.497 1.00 63.29  ? 339 ASN C OD1 1 
ATOM 6112 N ND2 . ASN C 1 265 ? 135.560 150.081 125.540 1.00 65.69  ? 339 ASN C ND2 1 
ATOM 6113 N N   . VAL C 1 266 ? 130.210 147.782 126.648 1.00 53.31  ? 340 VAL C N   1 
ATOM 6114 C CA  . VAL C 1 266 ? 128.797 147.658 126.306 1.00 49.35  ? 340 VAL C CA  1 
ATOM 6115 C C   . VAL C 1 266 ? 127.983 147.988 127.553 1.00 60.88  ? 340 VAL C C   1 
ATOM 6116 O O   . VAL C 1 266 ? 128.080 147.257 128.550 1.00 69.98  ? 340 VAL C O   1 
ATOM 6117 C CB  . VAL C 1 266 ? 128.465 146.253 125.795 1.00 47.84  ? 340 VAL C CB  1 
ATOM 6118 C CG1 . VAL C 1 266 ? 126.979 146.132 125.507 1.00 56.86  ? 340 VAL C CG1 1 
ATOM 6119 C CG2 . VAL C 1 266 ? 129.280 145.937 124.556 1.00 56.00  ? 340 VAL C CG2 1 
ATOM 6120 N N   . PRO C 1 267 ? 127.185 149.049 127.543 1.00 51.69  ? 341 PRO C N   1 
ATOM 6121 C CA  . PRO C 1 267 ? 126.407 149.407 128.737 1.00 47.04  ? 341 PRO C CA  1 
ATOM 6122 C C   . PRO C 1 267 ? 125.130 148.596 128.891 1.00 51.18  ? 341 PRO C C   1 
ATOM 6123 O O   . PRO C 1 267 ? 124.063 149.029 128.447 1.00 54.80  ? 341 PRO C O   1 
ATOM 6124 C CB  . PRO C 1 267 ? 126.107 150.892 128.513 1.00 47.69  ? 341 PRO C CB  1 
ATOM 6125 C CG  . PRO C 1 267 ? 126.054 151.027 127.032 1.00 45.91  ? 341 PRO C CG  1 
ATOM 6126 C CD  . PRO C 1 267 ? 127.069 150.063 126.482 1.00 47.56  ? 341 PRO C CD  1 
ATOM 6127 N N   . ALA C 1 268 ? 125.220 147.417 129.505 1.00 45.00  ? 342 ALA C N   1 
ATOM 6128 C CA  . ALA C 1 268 ? 124.056 146.557 129.653 1.00 44.46  ? 342 ALA C CA  1 
ATOM 6129 C C   . ALA C 1 268 ? 124.201 145.699 130.904 1.00 39.67  ? 342 ALA C C   1 
ATOM 6130 O O   . ALA C 1 268 ? 125.280 145.588 131.487 1.00 41.17  ? 342 ALA C O   1 
ATOM 6131 C CB  . ALA C 1 268 ? 123.859 145.692 128.411 1.00 43.33  ? 342 ALA C CB  1 
ATOM 6132 N N   . ILE C 1 269 ? 123.086 145.094 131.313 1.00 38.92  ? 343 ILE C N   1 
ATOM 6133 C CA  . ILE C 1 269 ? 123.015 144.231 132.488 1.00 37.13  ? 343 ILE C CA  1 
ATOM 6134 C C   . ILE C 1 269 ? 122.593 142.841 132.033 1.00 39.90  ? 343 ILE C C   1 
ATOM 6135 O O   . ILE C 1 269 ? 121.626 142.700 131.277 1.00 49.37  ? 343 ILE C O   1 
ATOM 6136 C CB  . ILE C 1 269 ? 122.027 144.770 133.539 1.00 33.89  ? 343 ILE C CB  1 
ATOM 6137 C CG1 . ILE C 1 269 ? 122.481 146.122 134.079 1.00 39.82  ? 343 ILE C CG1 1 
ATOM 6138 C CG2 . ILE C 1 269 ? 121.871 143.784 134.679 1.00 38.02  ? 343 ILE C CG2 1 
ATOM 6139 C CD1 . ILE C 1 269 ? 121.544 146.681 135.121 1.00 43.78  ? 343 ILE C CD1 1 
ATOM 6140 N N   . MET C 1 270 ? 123.302 141.822 132.504 1.00 31.75  ? 344 MET C N   1 
ATOM 6141 C CA  . MET C 1 270 ? 123.051 140.444 132.116 1.00 32.28  ? 344 MET C CA  1 
ATOM 6142 C C   . MET C 1 270 ? 122.229 139.719 133.173 1.00 43.47  ? 344 MET C C   1 
ATOM 6143 O O   . MET C 1 270 ? 122.304 140.029 134.364 1.00 51.33  ? 344 MET C O   1 
ATOM 6144 C CB  . MET C 1 270 ? 124.364 139.695 131.897 1.00 32.24  ? 344 MET C CB  1 
ATOM 6145 C CG  . MET C 1 270 ? 125.382 140.457 131.083 1.00 42.28  ? 344 MET C CG  1 
ATOM 6146 S SD  . MET C 1 270 ? 126.901 139.519 130.877 1.00 66.94  ? 344 MET C SD  1 
ATOM 6147 C CE  . MET C 1 270 ? 126.276 138.054 130.065 1.00 48.71  ? 344 MET C CE  1 
ATOM 6148 N N   . ILE C 1 271 ? 121.437 138.749 132.722 1.00 31.70  ? 345 ILE C N   1 
ATOM 6149 C CA  . ILE C 1 271 ? 120.696 137.848 133.599 1.00 22.89  ? 345 ILE C CA  1 
ATOM 6150 C C   . ILE C 1 271 ? 120.943 136.432 133.101 1.00 28.52  ? 345 ILE C C   1 
ATOM 6151 O O   . ILE C 1 271 ? 120.445 136.049 132.035 1.00 35.42  ? 345 ILE C O   1 
ATOM 6152 C CB  . ILE C 1 271 ? 119.195 138.164 133.634 1.00 18.93  ? 345 ILE C CB  1 
ATOM 6153 C CG1 . ILE C 1 271 ? 118.956 139.555 134.219 1.00 20.70  ? 345 ILE C CG1 1 
ATOM 6154 C CG2 . ILE C 1 271 ? 118.453 137.124 134.443 1.00 32.76  ? 345 ILE C CG2 1 
ATOM 6155 C CD1 . ILE C 1 271 ? 117.501 139.939 134.294 1.00 33.70  ? 345 ILE C CD1 1 
ATOM 6156 N N   . THR C 1 272 ? 121.707 135.655 133.865 1.00 36.01  ? 346 THR C N   1 
ATOM 6157 C CA  . THR C 1 272 ? 122.124 134.317 133.457 1.00 30.04  ? 346 THR C CA  1 
ATOM 6158 C C   . THR C 1 272 ? 121.719 133.319 134.533 1.00 41.61  ? 346 THR C C   1 
ATOM 6159 O O   . THR C 1 272 ? 122.142 133.462 135.698 1.00 49.21  ? 346 THR C O   1 
ATOM 6160 C CB  . THR C 1 272 ? 123.631 134.265 133.215 1.00 33.66  ? 346 THR C CB  1 
ATOM 6161 O OG1 . THR C 1 272 ? 123.995 135.260 132.251 1.00 43.60  ? 346 THR C OG1 1 
ATOM 6162 C CG2 . THR C 1 272 ? 124.034 132.899 132.692 1.00 34.13  ? 346 THR C CG2 1 
ATOM 6163 N N   . PRO C 1 273 ? 120.920 132.310 134.207 1.00 42.96  ? 347 PRO C N   1 
ATOM 6164 C CA  . PRO C 1 273 ? 120.521 131.314 135.205 1.00 43.66  ? 347 PRO C CA  1 
ATOM 6165 C C   . PRO C 1 273 ? 121.629 130.301 135.461 1.00 47.16  ? 347 PRO C C   1 
ATOM 6166 O O   . PRO C 1 273 ? 122.585 130.171 134.696 1.00 56.42  ? 347 PRO C O   1 
ATOM 6167 C CB  . PRO C 1 273 ? 119.310 130.644 134.557 1.00 37.80  ? 347 PRO C CB  1 
ATOM 6168 C CG  . PRO C 1 273 ? 119.581 130.758 133.103 1.00 40.40  ? 347 PRO C CG  1 
ATOM 6169 C CD  . PRO C 1 273 ? 120.272 132.076 132.907 1.00 38.99  ? 347 PRO C CD  1 
ATOM 6170 N N   . ILE C 1 274 ? 121.481 129.574 136.564 1.00 44.28  ? 348 ILE C N   1 
ATOM 6171 C CA  . ILE C 1 274 ? 122.377 128.479 136.912 1.00 45.31  ? 348 ILE C CA  1 
ATOM 6172 C C   . ILE C 1 274 ? 121.580 127.194 136.767 1.00 53.03  ? 348 ILE C C   1 
ATOM 6173 O O   . ILE C 1 274 ? 120.693 126.914 137.583 1.00 56.40  ? 348 ILE C O   1 
ATOM 6174 C CB  . ILE C 1 274 ? 122.930 128.609 138.335 1.00 48.46  ? 348 ILE C CB  1 
ATOM 6175 C CG1 . ILE C 1 274 ? 123.668 129.923 138.514 1.00 47.35  ? 348 ILE C CG1 1 
ATOM 6176 C CG2 . ILE C 1 274 ? 123.906 127.483 138.614 1.00 50.32  ? 348 ILE C CG2 1 
ATOM 6177 C CD1 . ILE C 1 274 ? 124.019 130.225 139.952 1.00 51.81  ? 348 ILE C CD1 1 
ATOM 6178 N N   . CYS C 1 275 ? 121.897 126.409 135.742 1.00 54.39  ? 349 CYS C N   1 
ATOM 6179 C CA  . CYS C 1 275 ? 121.238 125.134 135.487 1.00 51.97  ? 349 CYS C CA  1 
ATOM 6180 C C   . CYS C 1 275 ? 119.720 125.276 135.522 1.00 54.42  ? 349 CYS C C   1 
ATOM 6181 O O   . CYS C 1 275 ? 119.070 124.710 136.411 1.00 61.56  ? 349 CYS C O   1 
ATOM 6182 C CB  . CYS C 1 275 ? 121.693 124.090 136.507 1.00 56.71  ? 349 CYS C CB  1 
ATOM 6183 S SG  . CYS C 1 275 ? 123.467 123.771 136.506 1.00 58.95  ? 349 CYS C SG  1 
ATOM 6184 N N   . PRO C 1 276 ? 119.119 126.023 134.597 1.00 54.11  ? 350 PRO C N   1 
ATOM 6185 C CA  . PRO C 1 276 ? 117.662 126.168 134.610 1.00 52.45  ? 350 PRO C CA  1 
ATOM 6186 C C   . PRO C 1 276 ? 116.971 124.843 134.333 1.00 55.88  ? 350 PRO C C   1 
ATOM 6187 O O   . PRO C 1 276 ? 117.468 124.001 133.582 1.00 57.99  ? 350 PRO C O   1 
ATOM 6188 C CB  . PRO C 1 276 ? 117.397 127.181 133.492 1.00 57.92  ? 350 PRO C CB  1 
ATOM 6189 C CG  . PRO C 1 276 ? 118.547 127.018 132.572 1.00 58.36  ? 350 PRO C CG  1 
ATOM 6190 C CD  . PRO C 1 276 ? 119.727 126.711 133.445 1.00 59.13  ? 350 PRO C CD  1 
ATOM 6191 N N   . HIS C 1 277 ? 115.804 124.664 134.953 1.00 63.38  ? 351 HIS C N   1 
ATOM 6192 C CA  . HIS C 1 277 ? 115.056 123.427 134.768 1.00 64.56  ? 351 HIS C CA  1 
ATOM 6193 C C   . HIS C 1 277 ? 114.507 123.307 133.353 1.00 69.40  ? 351 HIS C C   1 
ATOM 6194 O O   . HIS C 1 277 ? 114.456 122.202 132.802 1.00 72.37  ? 351 HIS C O   1 
ATOM 6195 C CB  . HIS C 1 277 ? 113.923 123.341 135.788 1.00 65.85  ? 351 HIS C CB  1 
ATOM 6196 C CG  . HIS C 1 277 ? 113.109 122.090 135.683 1.00 74.20  ? 351 HIS C CG  1 
ATOM 6197 N ND1 . HIS C 1 277 ? 113.641 120.835 135.887 1.00 74.25  ? 351 HIS C ND1 1 
ATOM 6198 C CD2 . HIS C 1 277 ? 111.799 121.900 135.394 1.00 74.25  ? 351 HIS C CD2 1 
ATOM 6199 C CE1 . HIS C 1 277 ? 112.695 119.927 135.729 1.00 75.63  ? 351 HIS C CE1 1 
ATOM 6200 N NE2 . HIS C 1 277 ? 111.568 120.547 135.429 1.00 73.63  ? 351 HIS C NE2 1 
ATOM 6201 N N   . SER C 1 278 ? 114.097 124.420 132.752 1.00 65.16  ? 352 SER C N   1 
ATOM 6202 C CA  . SER C 1 278 ? 113.555 124.418 131.400 1.00 62.34  ? 352 SER C CA  1 
ATOM 6203 C C   . SER C 1 278 ? 114.689 124.480 130.387 1.00 60.12  ? 352 SER C C   1 
ATOM 6204 O O   . SER C 1 278 ? 115.587 125.320 130.501 1.00 64.97  ? 352 SER C O   1 
ATOM 6205 C CB  . SER C 1 278 ? 112.601 125.594 131.200 1.00 64.63  ? 352 SER C CB  1 
ATOM 6206 O OG  . SER C 1 278 ? 113.280 126.825 131.355 1.00 62.39  ? 352 SER C OG  1 
ATOM 6207 N N   . LEU C 1 279 ? 114.639 123.590 129.395 1.00 58.26  ? 353 LEU C N   1 
ATOM 6208 C CA  . LEU C 1 279 ? 115.698 123.527 128.393 1.00 61.88  ? 353 LEU C CA  1 
ATOM 6209 C C   . LEU C 1 279 ? 115.765 124.798 127.558 1.00 61.54  ? 353 LEU C C   1 
ATOM 6210 O O   . LEU C 1 279 ? 116.859 125.245 127.197 1.00 62.21  ? 353 LEU C O   1 
ATOM 6211 C CB  . LEU C 1 279 ? 115.488 122.311 127.494 1.00 63.29  ? 353 LEU C CB  1 
ATOM 6212 C CG  . LEU C 1 279 ? 115.492 120.958 128.207 1.00 66.84  ? 353 LEU C CG  1 
ATOM 6213 C CD1 . LEU C 1 279 ? 115.207 119.834 127.228 1.00 63.51  ? 353 LEU C CD1 1 
ATOM 6214 C CD2 . LEU C 1 279 ? 116.820 120.733 128.910 1.00 64.40  ? 353 LEU C CD2 1 
ATOM 6215 N N   . SER C 1 280 ? 114.614 125.388 127.234 1.00 60.59  ? 354 SER C N   1 
ATOM 6216 C CA  . SER C 1 280 ? 114.561 126.601 126.422 1.00 62.07  ? 354 SER C CA  1 
ATOM 6217 C C   . SER C 1 280 ? 114.473 127.809 127.350 1.00 62.12  ? 354 SER C C   1 
ATOM 6218 O O   . SER C 1 280 ? 113.436 128.455 127.482 1.00 61.92  ? 354 SER C O   1 
ATOM 6219 C CB  . SER C 1 280 ? 113.386 126.549 125.452 1.00 61.13  ? 354 SER C CB  1 
ATOM 6220 O OG  . SER C 1 280 ? 113.362 127.693 124.617 1.00 62.50  ? 354 SER C OG  1 
ATOM 6221 N N   . PHE C 1 281 ? 115.591 128.105 128.008 1.00 59.22  ? 355 PHE C N   1 
ATOM 6222 C CA  . PHE C 1 281 ? 115.709 129.310 128.826 1.00 57.42  ? 355 PHE C CA  1 
ATOM 6223 C C   . PHE C 1 281 ? 117.167 129.729 128.807 1.00 52.85  ? 355 PHE C C   1 
ATOM 6224 O O   . PHE C 1 281 ? 118.016 129.035 129.376 1.00 56.16  ? 355 PHE C O   1 
ATOM 6225 C CB  . PHE C 1 281 ? 115.227 129.070 130.255 1.00 53.82  ? 355 PHE C CB  1 
ATOM 6226 C CG  . PHE C 1 281 ? 115.257 130.298 131.121 1.00 59.25  ? 355 PHE C CG  1 
ATOM 6227 C CD1 . PHE C 1 281 ? 114.308 131.294 130.964 1.00 59.73  ? 355 PHE C CD1 1 
ATOM 6228 C CD2 . PHE C 1 281 ? 116.220 130.452 132.100 1.00 61.27  ? 355 PHE C CD2 1 
ATOM 6229 C CE1 . PHE C 1 281 ? 114.328 132.424 131.759 1.00 61.36  ? 355 PHE C CE1 1 
ATOM 6230 C CE2 . PHE C 1 281 ? 116.244 131.579 132.899 1.00 60.12  ? 355 PHE C CE2 1 
ATOM 6231 C CZ  . PHE C 1 281 ? 115.299 132.565 132.729 1.00 61.83  ? 355 PHE C CZ  1 
ATOM 6232 N N   . ARG C 1 282 ? 117.456 130.847 128.164 1.00 51.21  ? 356 ARG C N   1 
ATOM 6233 C CA  . ARG C 1 282 ? 118.812 131.248 127.836 1.00 50.71  ? 356 ARG C CA  1 
ATOM 6234 C C   . ARG C 1 282 ? 119.124 132.581 128.492 1.00 56.92  ? 356 ARG C C   1 
ATOM 6235 O O   . ARG C 1 282 ? 118.213 133.347 128.824 1.00 62.77  ? 356 ARG C O   1 
ATOM 6236 C CB  . ARG C 1 282 ? 118.985 131.360 126.315 1.00 54.71  ? 356 ARG C CB  1 
ATOM 6237 C CG  . ARG C 1 282 ? 118.362 130.217 125.550 1.00 60.95  ? 356 ARG C CG  1 
ATOM 6238 C CD  . ARG C 1 282 ? 118.494 130.445 124.068 1.00 59.83  ? 356 ARG C CD  1 
ATOM 6239 N NE  . ARG C 1 282 ? 119.890 130.618 123.695 1.00 57.10  ? 356 ARG C NE  1 
ATOM 6240 C CZ  . ARG C 1 282 ? 120.715 129.616 123.429 1.00 60.47  ? 356 ARG C CZ  1 
ATOM 6241 N NH1 . ARG C 1 282 ? 120.306 128.359 123.456 1.00 59.54  ? 356 ARG C NH1 1 
ATOM 6242 N NH2 . ARG C 1 282 ? 121.984 129.881 123.136 1.00 59.64  ? 356 ARG C NH2 1 
ATOM 6243 N N   . PRO C 1 283 ? 120.404 132.881 128.710 1.00 35.13  ? 357 PRO C N   1 
ATOM 6244 C CA  . PRO C 1 283 ? 120.759 134.167 129.318 1.00 35.09  ? 357 PRO C CA  1 
ATOM 6245 C C   . PRO C 1 283 ? 120.285 135.330 128.465 1.00 34.25  ? 357 PRO C C   1 
ATOM 6246 O O   . PRO C 1 283 ? 120.338 135.286 127.235 1.00 44.30  ? 357 PRO C O   1 
ATOM 6247 C CB  . PRO C 1 283 ? 122.289 134.112 129.397 1.00 33.88  ? 357 PRO C CB  1 
ATOM 6248 C CG  . PRO C 1 283 ? 122.688 133.048 128.430 1.00 34.99  ? 357 PRO C CG  1 
ATOM 6249 C CD  . PRO C 1 283 ? 121.592 132.045 128.479 1.00 37.94  ? 357 PRO C CD  1 
ATOM 6250 N N   . ILE C 1 284 ? 119.815 136.377 129.131 1.00 19.03  ? 358 ILE C N   1 
ATOM 6251 C CA  . ILE C 1 284 ? 119.370 137.588 128.460 1.00 25.62  ? 358 ILE C CA  1 
ATOM 6252 C C   . ILE C 1 284 ? 120.202 138.749 128.975 1.00 33.49  ? 358 ILE C C   1 
ATOM 6253 O O   . ILE C 1 284 ? 120.775 138.692 130.068 1.00 40.29  ? 358 ILE C O   1 
ATOM 6254 C CB  . ILE C 1 284 ? 117.868 137.865 128.676 1.00 30.34  ? 358 ILE C CB  1 
ATOM 6255 C CG1 . ILE C 1 284 ? 117.589 138.190 130.140 1.00 27.19  ? 358 ILE C CG1 1 
ATOM 6256 C CG2 . ILE C 1 284 ? 117.039 136.674 128.243 1.00 36.40  ? 358 ILE C CG2 1 
ATOM 6257 C CD1 . ILE C 1 284 ? 116.169 138.619 130.402 1.00 33.99  ? 358 ILE C CD1 1 
ATOM 6258 N N   . VAL C 1 285 ? 120.276 139.805 128.175 1.00 40.36  ? 359 VAL C N   1 
ATOM 6259 C CA  . VAL C 1 285 ? 120.943 141.035 128.573 1.00 29.31  ? 359 VAL C CA  1 
ATOM 6260 C C   . VAL C 1 285 ? 119.991 142.195 128.308 1.00 31.46  ? 359 VAL C C   1 
ATOM 6261 O O   . VAL C 1 285 ? 119.316 142.238 127.274 1.00 47.42  ? 359 VAL C O   1 
ATOM 6262 C CB  . VAL C 1 285 ? 122.294 141.217 127.848 1.00 17.97  ? 359 VAL C CB  1 
ATOM 6263 C CG1 . VAL C 1 285 ? 122.103 141.432 126.375 1.00 29.43  ? 359 VAL C CG1 1 
ATOM 6264 C CG2 . VAL C 1 285 ? 123.085 142.340 128.468 1.00 35.42  ? 359 VAL C CG2 1 
ATOM 6265 N N   . VAL C 1 286 ? 119.908 143.109 129.263 1.00 24.76  ? 360 VAL C N   1 
ATOM 6266 C CA  . VAL C 1 286 ? 118.888 144.153 129.269 1.00 17.42  ? 360 VAL C CA  1 
ATOM 6267 C C   . VAL C 1 286 ? 119.605 145.495 129.283 1.00 27.28  ? 360 VAL C C   1 
ATOM 6268 O O   . VAL C 1 286 ? 120.804 145.567 129.601 1.00 44.11  ? 360 VAL C O   1 
ATOM 6269 C CB  . VAL C 1 286 ? 117.922 143.998 130.466 1.00 31.07  ? 360 VAL C CB  1 
ATOM 6270 C CG1 . VAL C 1 286 ? 117.188 142.676 130.380 1.00 31.32  ? 360 VAL C CG1 1 
ATOM 6271 C CG2 . VAL C 1 286 ? 118.682 144.098 131.773 1.00 42.56  ? 360 VAL C CG2 1 
ATOM 6272 N N   . PRO C 1 287 ? 118.912 146.580 128.929 1.00 17.85  ? 361 PRO C N   1 
ATOM 6273 C CA  . PRO C 1 287 ? 119.560 147.897 128.942 1.00 26.28  ? 361 PRO C CA  1 
ATOM 6274 C C   . PRO C 1 287 ? 120.082 148.254 130.324 1.00 40.63  ? 361 PRO C C   1 
ATOM 6275 O O   . PRO C 1 287 ? 119.551 147.819 131.346 1.00 45.62  ? 361 PRO C O   1 
ATOM 6276 C CB  . PRO C 1 287 ? 118.441 148.846 128.505 1.00 26.10  ? 361 PRO C CB  1 
ATOM 6277 C CG  . PRO C 1 287 ? 117.537 148.001 127.708 1.00 32.45  ? 361 PRO C CG  1 
ATOM 6278 C CD  . PRO C 1 287 ? 117.562 146.648 128.345 1.00 25.53  ? 361 PRO C CD  1 
ATOM 6279 N N   . ALA C 1 288 ? 121.156 149.048 130.342 1.00 36.65  ? 362 ALA C N   1 
ATOM 6280 C CA  . ALA C 1 288 ? 121.829 149.358 131.599 1.00 29.99  ? 362 ALA C CA  1 
ATOM 6281 C C   . ALA C 1 288 ? 120.931 150.125 132.559 1.00 38.42  ? 362 ALA C C   1 
ATOM 6282 O O   . ALA C 1 288 ? 120.919 149.833 133.761 1.00 42.61  ? 362 ALA C O   1 
ATOM 6283 C CB  . ALA C 1 288 ? 123.105 150.154 131.328 1.00 40.11  ? 362 ALA C CB  1 
ATOM 6284 N N   . GLY C 1 289 ? 120.178 151.099 132.061 1.00 46.00  ? 363 GLY C N   1 
ATOM 6285 C CA  . GLY C 1 289 ? 119.390 151.968 132.908 1.00 47.52  ? 363 GLY C CA  1 
ATOM 6286 C C   . GLY C 1 289 ? 118.097 151.394 133.435 1.00 52.11  ? 363 GLY C C   1 
ATOM 6287 O O   . GLY C 1 289 ? 117.182 152.158 133.750 1.00 56.70  ? 363 GLY C O   1 
ATOM 6288 N N   . VAL C 1 290 ? 117.986 150.083 133.545 1.00 50.25  ? 364 VAL C N   1 
ATOM 6289 C CA  . VAL C 1 290 ? 116.759 149.451 134.010 1.00 47.81  ? 364 VAL C CA  1 
ATOM 6290 C C   . VAL C 1 290 ? 116.890 149.162 135.498 1.00 53.03  ? 364 VAL C C   1 
ATOM 6291 O O   . VAL C 1 290 ? 117.995 149.027 136.033 1.00 53.87  ? 364 VAL C O   1 
ATOM 6292 C CB  . VAL C 1 290 ? 116.463 148.167 133.206 1.00 47.84  ? 364 VAL C CB  1 
ATOM 6293 C CG1 . VAL C 1 290 ? 117.482 147.091 133.524 1.00 49.25  ? 364 VAL C CG1 1 
ATOM 6294 C CG2 . VAL C 1 290 ? 115.056 147.684 133.465 1.00 55.36  ? 364 VAL C CG2 1 
ATOM 6295 N N   . GLU C 1 291 ? 115.751 149.078 136.181 1.00 57.37  ? 365 GLU C N   1 
ATOM 6296 C CA  . GLU C 1 291 ? 115.703 148.731 137.594 1.00 54.92  ? 365 GLU C CA  1 
ATOM 6297 C C   . GLU C 1 291 ? 115.174 147.309 137.730 1.00 53.75  ? 365 GLU C C   1 
ATOM 6298 O O   . GLU C 1 291 ? 113.996 147.053 137.462 1.00 56.82  ? 365 GLU C O   1 
ATOM 6299 C CB  . GLU C 1 291 ? 114.824 149.717 138.365 1.00 55.55  ? 365 GLU C CB  1 
ATOM 6300 C CG  . GLU C 1 291 ? 114.894 149.587 139.880 1.00 61.34  ? 365 GLU C CG  1 
ATOM 6301 C CD  . GLU C 1 291 ? 113.950 148.534 140.429 1.00 65.82  ? 365 GLU C CD  1 
ATOM 6302 O OE1 . GLU C 1 291 ? 112.900 148.288 139.799 1.00 63.02  ? 365 GLU C OE1 1 
ATOM 6303 O OE2 . GLU C 1 291 ? 114.256 147.955 141.492 1.00 65.24  ? 365 GLU C OE2 1 
ATOM 6304 N N   . LEU C 1 292 ? 116.042 146.390 138.140 1.00 47.37  ? 366 LEU C N   1 
ATOM 6305 C CA  . LEU C 1 292 ? 115.664 145.008 138.387 1.00 48.04  ? 366 LEU C CA  1 
ATOM 6306 C C   . LEU C 1 292 ? 115.226 144.835 139.834 1.00 54.10  ? 366 LEU C C   1 
ATOM 6307 O O   . LEU C 1 292 ? 115.639 145.584 140.722 1.00 61.48  ? 366 LEU C O   1 
ATOM 6308 C CB  . LEU C 1 292 ? 116.818 144.053 138.082 1.00 43.59  ? 366 LEU C CB  1 
ATOM 6309 C CG  . LEU C 1 292 ? 117.250 143.905 136.627 1.00 50.13  ? 366 LEU C CG  1 
ATOM 6310 C CD1 . LEU C 1 292 ? 118.406 142.932 136.523 1.00 60.45  ? 366 LEU C CD1 1 
ATOM 6311 C CD2 . LEU C 1 292 ? 116.084 143.438 135.783 1.00 55.25  ? 366 LEU C CD2 1 
ATOM 6312 N N   . LYS C 1 293 ? 114.386 143.830 140.063 1.00 47.10  ? 367 LYS C N   1 
ATOM 6313 C CA  . LYS C 1 293 ? 113.862 143.537 141.391 1.00 43.29  ? 367 LYS C CA  1 
ATOM 6314 C C   . LYS C 1 293 ? 113.590 142.044 141.474 1.00 47.80  ? 367 LYS C C   1 
ATOM 6315 O O   . LYS C 1 293 ? 112.759 141.523 140.726 1.00 55.82  ? 367 LYS C O   1 
ATOM 6316 C CB  . LYS C 1 293 ? 112.590 144.342 141.668 1.00 46.29  ? 367 LYS C CB  1 
ATOM 6317 C CG  . LYS C 1 293 ? 112.076 144.251 143.089 1.00 46.12  ? 367 LYS C CG  1 
ATOM 6318 C CD  . LYS C 1 293 ? 110.892 145.182 143.286 1.00 49.15  ? 367 LYS C CD  1 
ATOM 6319 C CE  . LYS C 1 293 ? 110.394 145.161 144.719 1.00 53.96  ? 367 LYS C CE  1 
ATOM 6320 N NZ  . LYS C 1 293 ? 109.971 143.797 145.140 1.00 55.68  ? 367 LYS C NZ  1 
ATOM 6321 N N   . ILE C 1 294 ? 114.288 141.360 142.374 1.00 40.05  ? 368 ILE C N   1 
ATOM 6322 C CA  . ILE C 1 294 ? 114.194 139.913 142.519 1.00 39.87  ? 368 ILE C CA  1 
ATOM 6323 C C   . ILE C 1 294 ? 113.670 139.607 143.915 1.00 49.72  ? 368 ILE C C   1 
ATOM 6324 O O   . ILE C 1 294 ? 114.180 140.141 144.906 1.00 55.26  ? 368 ILE C O   1 
ATOM 6325 C CB  . ILE C 1 294 ? 115.553 139.232 142.276 1.00 29.05  ? 368 ILE C CB  1 
ATOM 6326 C CG1 . ILE C 1 294 ? 115.995 139.420 140.827 1.00 37.06  ? 368 ILE C CG1 1 
ATOM 6327 C CG2 . ILE C 1 294 ? 115.485 137.763 142.613 1.00 39.22  ? 368 ILE C CG2 1 
ATOM 6328 C CD1 . ILE C 1 294 ? 117.308 138.756 140.509 1.00 45.14  ? 368 ILE C CD1 1 
ATOM 6329 N N   . MET C 1 295 ? 112.648 138.758 143.991 1.00 56.19  ? 369 MET C N   1 
ATOM 6330 C CA  . MET C 1 295 ? 112.042 138.405 145.265 1.00 45.46  ? 369 MET C CA  1 
ATOM 6331 C C   . MET C 1 295 ? 111.447 137.011 145.162 1.00 47.12  ? 369 MET C C   1 
ATOM 6332 O O   . MET C 1 295 ? 111.035 136.576 144.085 1.00 53.74  ? 369 MET C O   1 
ATOM 6333 C CB  . MET C 1 295 ? 110.964 139.416 145.671 1.00 52.67  ? 369 MET C CB  1 
ATOM 6334 C CG  . MET C 1 295 ? 109.869 139.603 144.634 1.00 60.11  ? 369 MET C CG  1 
ATOM 6335 S SD  . MET C 1 295 ? 108.745 140.952 145.035 1.00 67.05  ? 369 MET C SD  1 
ATOM 6336 C CE  . MET C 1 295 ? 108.125 140.413 146.625 1.00 53.91  ? 369 MET C CE  1 
ATOM 6337 N N   . LEU C 1 296 ? 111.404 136.317 146.296 1.00 47.55  ? 370 LEU C N   1 
ATOM 6338 C CA  . LEU C 1 296 ? 110.900 134.952 146.314 1.00 53.29  ? 370 LEU C CA  1 
ATOM 6339 C C   . LEU C 1 296 ? 109.423 134.916 145.949 1.00 62.75  ? 370 LEU C C   1 
ATOM 6340 O O   . LEU C 1 296 ? 108.632 135.748 146.402 1.00 71.46  ? 370 LEU C O   1 
ATOM 6341 C CB  . LEU C 1 296 ? 111.111 134.324 147.690 1.00 52.98  ? 370 LEU C CB  1 
ATOM 6342 C CG  . LEU C 1 296 ? 112.544 133.959 148.069 1.00 58.59  ? 370 LEU C CG  1 
ATOM 6343 C CD1 . LEU C 1 296 ? 112.559 133.189 149.377 1.00 58.36  ? 370 LEU C CD1 1 
ATOM 6344 C CD2 . LEU C 1 296 ? 113.199 133.152 146.963 1.00 64.36  ? 370 LEU C CD2 1 
ATOM 6345 N N   . SER C 1 297 ? 109.055 133.945 145.120 1.00 62.38  ? 371 SER C N   1 
ATOM 6346 C CA  . SER C 1 297 ? 107.661 133.784 144.745 1.00 60.71  ? 371 SER C CA  1 
ATOM 6347 C C   . SER C 1 297 ? 106.842 133.366 145.964 1.00 65.98  ? 371 SER C C   1 
ATOM 6348 O O   . SER C 1 297 ? 107.307 132.562 146.777 1.00 67.58  ? 371 SER C O   1 
ATOM 6349 C CB  . SER C 1 297 ? 107.520 132.748 143.633 1.00 64.86  ? 371 SER C CB  1 
ATOM 6350 O OG  . SER C 1 297 ? 108.073 131.505 144.022 1.00 67.76  ? 371 SER C OG  1 
ATOM 6351 N N   . PRO C 1 298 ? 105.632 133.903 146.126 1.00 66.03  ? 372 PRO C N   1 
ATOM 6352 C CA  . PRO C 1 298 ? 104.846 133.583 147.328 1.00 62.76  ? 372 PRO C CA  1 
ATOM 6353 C C   . PRO C 1 298 ? 104.536 132.106 147.479 1.00 61.88  ? 372 PRO C C   1 
ATOM 6354 O O   . PRO C 1 298 ? 104.498 131.603 148.608 1.00 65.21  ? 372 PRO C O   1 
ATOM 6355 C CB  . PRO C 1 298 ? 103.571 134.417 147.142 1.00 68.51  ? 372 PRO C CB  1 
ATOM 6356 C CG  . PRO C 1 298 ? 103.481 134.650 145.671 1.00 69.45  ? 372 PRO C CG  1 
ATOM 6357 C CD  . PRO C 1 298 ? 104.895 134.773 145.195 1.00 66.02  ? 372 PRO C CD  1 
ATOM 6358 N N   . GLU C 1 299 ? 104.315 131.391 146.377 1.00 74.76  ? 373 GLU C N   1 
ATOM 6359 C CA  . GLU C 1 299 ? 104.042 129.958 146.425 1.00 79.70  ? 373 GLU C CA  1 
ATOM 6360 C C   . GLU C 1 299 ? 105.361 129.232 146.172 1.00 79.90  ? 373 GLU C C   1 
ATOM 6361 O O   . GLU C 1 299 ? 105.657 128.776 145.069 1.00 80.42  ? 373 GLU C O   1 
ATOM 6362 C CB  . GLU C 1 299 ? 102.957 129.583 145.415 1.00 80.90  ? 373 GLU C CB  1 
ATOM 6363 C CG  . GLU C 1 299 ? 102.385 128.175 145.575 1.00 82.85  ? 373 GLU C CG  1 
ATOM 6364 C CD  . GLU C 1 299 ? 103.160 127.119 144.810 1.00 84.23  ? 373 GLU C CD  1 
ATOM 6365 O OE1 . GLU C 1 299 ? 103.726 127.444 143.746 1.00 85.34  ? 373 GLU C OE1 1 
ATOM 6366 O OE2 . GLU C 1 299 ? 103.200 125.959 145.274 1.00 83.03  ? 373 GLU C OE2 1 
ATOM 6367 N N   . ALA C 1 300 ? 106.174 129.152 147.223 1.00 65.30  ? 374 ALA C N   1 
ATOM 6368 C CA  . ALA C 1 300 ? 107.477 128.506 147.138 1.00 62.37  ? 374 ALA C CA  1 
ATOM 6369 C C   . ALA C 1 300 ? 107.977 128.218 148.543 1.00 64.28  ? 374 ALA C C   1 
ATOM 6370 O O   . ALA C 1 300 ? 108.018 129.120 149.384 1.00 62.01  ? 374 ALA C O   1 
ATOM 6371 C CB  . ALA C 1 300 ? 108.485 129.381 146.388 1.00 66.73  ? 374 ALA C CB  1 
ATOM 6372 N N   . ARG C 1 301 ? 108.356 126.968 148.790 1.00 76.88  ? 375 ARG C N   1 
ATOM 6373 C CA  . ARG C 1 301 ? 108.901 126.587 150.081 1.00 80.83  ? 375 ARG C CA  1 
ATOM 6374 C C   . ARG C 1 301 ? 110.378 126.964 150.167 1.00 81.44  ? 375 ARG C C   1 
ATOM 6375 O O   . ARG C 1 301 ? 111.020 127.312 149.172 1.00 84.07  ? 375 ARG C O   1 
ATOM 6376 C CB  . ARG C 1 301 ? 108.721 125.087 150.323 1.00 80.74  ? 375 ARG C CB  1 
ATOM 6377 C CG  . ARG C 1 301 ? 107.273 124.656 150.491 1.00 80.20  ? 375 ARG C CG  1 
ATOM 6378 C CD  . ARG C 1 301 ? 107.096 123.173 150.779 1.00 83.32  ? 375 ARG C CD  1 
ATOM 6379 N NE  . ARG C 1 301 ? 105.688 122.796 150.863 1.00 84.41  ? 375 ARG C NE  1 
ATOM 6380 C CZ  . ARG C 1 301 ? 105.258 121.549 150.990 1.00 82.32  ? 375 ARG C CZ  1 
ATOM 6381 N NH1 . ARG C 1 301 ? 106.127 120.548 151.053 1.00 80.28  ? 375 ARG C NH1 1 
ATOM 6382 N NH2 . ARG C 1 301 ? 103.957 121.297 151.058 1.00 81.83  ? 375 ARG C NH2 1 
ATOM 6383 N N   . ASN C 1 302 ? 110.911 126.898 151.389 1.00 72.91  ? 376 ASN C N   1 
ATOM 6384 C CA  . ASN C 1 302 ? 112.313 127.194 151.669 1.00 68.93  ? 376 ASN C CA  1 
ATOM 6385 C C   . ASN C 1 302 ? 112.686 128.617 151.274 1.00 65.01  ? 376 ASN C C   1 
ATOM 6386 O O   . ASN C 1 302 ? 111.819 129.420 150.915 1.00 69.33  ? 376 ASN C O   1 
ATOM 6387 C CB  . ASN C 1 302 ? 113.224 126.186 150.965 1.00 68.93  ? 376 ASN C CB  1 
ATOM 6388 C CG  . ASN C 1 302 ? 112.777 124.756 151.177 1.00 75.50  ? 376 ASN C CG  1 
ATOM 6389 O OD1 . ASN C 1 302 ? 112.509 124.338 152.303 1.00 74.62  ? 376 ASN C OD1 1 
ATOM 6390 N ND2 . ASN C 1 302 ? 112.694 123.995 150.094 1.00 76.77  ? 376 ASN C ND2 1 
ATOM 6391 N N   . THR C 1 303 ? 113.973 128.943 151.354 1.00 53.05  ? 377 THR C N   1 
ATOM 6392 C CA  . THR C 1 303 ? 114.451 130.290 151.091 1.00 53.54  ? 377 THR C CA  1 
ATOM 6393 C C   . THR C 1 303 ? 115.706 130.217 150.235 1.00 61.15  ? 377 THR C C   1 
ATOM 6394 O O   . THR C 1 303 ? 116.279 129.146 150.021 1.00 67.40  ? 377 THR C O   1 
ATOM 6395 C CB  . THR C 1 303 ? 114.738 131.052 152.389 1.00 60.36  ? 377 THR C CB  1 
ATOM 6396 O OG1 . THR C 1 303 ? 115.513 130.227 153.266 1.00 62.52  ? 377 THR C OG1 1 
ATOM 6397 C CG2 . THR C 1 303 ? 113.440 131.439 153.078 1.00 62.38  ? 377 THR C CG2 1 
ATOM 6398 N N   . ALA C 1 304 ? 116.130 131.377 149.744 1.00 63.11  ? 378 ALA C N   1 
ATOM 6399 C CA  . ALA C 1 304 ? 117.303 131.499 148.895 1.00 59.90  ? 378 ALA C CA  1 
ATOM 6400 C C   . ALA C 1 304 ? 118.338 132.391 149.567 1.00 54.11  ? 378 ALA C C   1 
ATOM 6401 O O   . ALA C 1 304 ? 118.039 133.143 150.497 1.00 60.55  ? 378 ALA C O   1 
ATOM 6402 C CB  . ALA C 1 304 ? 116.931 132.057 147.515 1.00 58.45  ? 378 ALA C CB  1 
ATOM 6403 N N   . TRP C 1 305 ? 119.571 132.296 149.080 1.00 44.30  ? 379 TRP C N   1 
ATOM 6404 C CA  . TRP C 1 305 ? 120.691 133.050 149.618 1.00 52.05  ? 379 TRP C CA  1 
ATOM 6405 C C   . TRP C 1 305 ? 121.292 133.918 148.524 1.00 55.51  ? 379 TRP C C   1 
ATOM 6406 O O   . TRP C 1 305 ? 121.313 133.540 147.350 1.00 66.15  ? 379 TRP C O   1 
ATOM 6407 C CB  . TRP C 1 305 ? 121.758 132.117 150.200 1.00 58.44  ? 379 TRP C CB  1 
ATOM 6408 C CG  . TRP C 1 305 ? 121.289 131.348 151.397 1.00 60.86  ? 379 TRP C CG  1 
ATOM 6409 C CD1 . TRP C 1 305 ? 120.556 130.202 151.396 1.00 56.23  ? 379 TRP C CD1 1 
ATOM 6410 C CD2 . TRP C 1 305 ? 121.541 131.662 152.771 1.00 50.57  ? 379 TRP C CD2 1 
ATOM 6411 N NE1 . TRP C 1 305 ? 120.325 129.787 152.683 1.00 55.66  ? 379 TRP C NE1 1 
ATOM 6412 C CE2 . TRP C 1 305 ? 120.922 130.666 153.546 1.00 48.31  ? 379 TRP C CE2 1 
ATOM 6413 C CE3 . TRP C 1 305 ? 122.230 132.690 153.419 1.00 47.27  ? 379 TRP C CE3 1 
ATOM 6414 C CZ2 . TRP C 1 305 ? 120.967 130.667 154.936 1.00 53.98  ? 379 TRP C CZ2 1 
ATOM 6415 C CZ3 . TRP C 1 305 ? 122.274 132.690 154.799 1.00 54.61  ? 379 TRP C CZ3 1 
ATOM 6416 C CH2 . TRP C 1 305 ? 121.647 131.685 155.543 1.00 58.14  ? 379 TRP C CH2 1 
ATOM 6417 N N   . VAL C 1 306 ? 121.784 135.089 148.919 1.00 32.99  ? 380 VAL C N   1 
ATOM 6418 C CA  . VAL C 1 306 ? 122.331 136.069 147.991 1.00 22.43  ? 380 VAL C CA  1 
ATOM 6419 C C   . VAL C 1 306 ? 123.802 136.289 148.311 1.00 34.96  ? 380 VAL C C   1 
ATOM 6420 O O   . VAL C 1 306 ? 124.190 136.370 149.482 1.00 51.51  ? 380 VAL C O   1 
ATOM 6421 C CB  . VAL C 1 306 ? 121.549 137.398 148.035 1.00 29.09  ? 380 VAL C CB  1 
ATOM 6422 C CG1 . VAL C 1 306 ? 121.595 138.013 149.418 1.00 36.53  ? 380 VAL C CG1 1 
ATOM 6423 C CG2 . VAL C 1 306 ? 122.095 138.366 147.009 1.00 40.33  ? 380 VAL C CG2 1 
ATOM 6424 N N   . SER C 1 307 ? 124.624 136.360 147.267 1.00 39.24  ? 381 SER C N   1 
ATOM 6425 C CA  . SER C 1 307 ? 126.047 136.622 147.401 1.00 42.71  ? 381 SER C CA  1 
ATOM 6426 C C   . SER C 1 307 ? 126.427 137.817 146.542 1.00 43.59  ? 381 SER C C   1 
ATOM 6427 O O   . SER C 1 307 ? 125.831 138.058 145.489 1.00 53.10  ? 381 SER C O   1 
ATOM 6428 C CB  . SER C 1 307 ? 126.882 135.403 147.000 1.00 47.53  ? 381 SER C CB  1 
ATOM 6429 O OG  . SER C 1 307 ? 126.623 135.029 145.659 1.00 48.94  ? 381 SER C OG  1 
ATOM 6430 N N   . PHE C 1 308 ? 127.429 138.566 147.001 1.00 40.04  ? 382 PHE C N   1 
ATOM 6431 C CA  . PHE C 1 308 ? 127.901 139.774 146.323 1.00 45.06  ? 382 PHE C CA  1 
ATOM 6432 C C   . PHE C 1 308 ? 129.394 139.620 146.051 1.00 48.07  ? 382 PHE C C   1 
ATOM 6433 O O   . PHE C 1 308 ? 130.218 139.959 146.903 1.00 51.68  ? 382 PHE C O   1 
ATOM 6434 C CB  . PHE C 1 308 ? 127.616 141.013 147.157 1.00 44.57  ? 382 PHE C CB  1 
ATOM 6435 C CG  . PHE C 1 308 ? 126.203 141.100 147.647 1.00 45.70  ? 382 PHE C CG  1 
ATOM 6436 C CD1 . PHE C 1 308 ? 125.226 141.695 146.873 1.00 41.68  ? 382 PHE C CD1 1 
ATOM 6437 C CD2 . PHE C 1 308 ? 125.853 140.596 148.886 1.00 48.05  ? 382 PHE C CD2 1 
ATOM 6438 C CE1 . PHE C 1 308 ? 123.928 141.779 147.321 1.00 44.75  ? 382 PHE C CE1 1 
ATOM 6439 C CE2 . PHE C 1 308 ? 124.555 140.679 149.339 1.00 49.35  ? 382 PHE C CE2 1 
ATOM 6440 C CZ  . PHE C 1 308 ? 123.592 141.271 148.555 1.00 50.98  ? 382 PHE C CZ  1 
ATOM 6441 N N   . ASP C 1 309 ? 129.734 139.122 144.862 1.00 51.00  ? 383 ASP C N   1 
ATOM 6442 C CA  . ASP C 1 309 ? 131.127 138.928 144.457 1.00 51.81  ? 383 ASP C CA  1 
ATOM 6443 C C   . ASP C 1 309 ? 131.869 138.017 145.432 1.00 59.80  ? 383 ASP C C   1 
ATOM 6444 O O   . ASP C 1 309 ? 133.023 138.265 145.786 1.00 63.31  ? 383 ASP C O   1 
ATOM 6445 C CB  . ASP C 1 309 ? 131.856 140.266 144.311 1.00 56.34  ? 383 ASP C CB  1 
ATOM 6446 C CG  . ASP C 1 309 ? 131.303 141.110 143.187 1.00 61.85  ? 383 ASP C CG  1 
ATOM 6447 O OD1 . ASP C 1 309 ? 130.847 140.535 142.177 1.00 61.09  ? 383 ASP C OD1 1 
ATOM 6448 O OD2 . ASP C 1 309 ? 131.331 142.352 143.311 1.00 65.82  ? 383 ASP C OD2 1 
ATOM 6449 N N   . GLY C 1 310 ? 131.206 136.953 145.867 1.00 49.90  ? 384 GLY C N   1 
ATOM 6450 C CA  . GLY C 1 310 ? 131.810 136.043 146.822 1.00 47.40  ? 384 GLY C CA  1 
ATOM 6451 C C   . GLY C 1 310 ? 132.046 136.656 148.184 1.00 50.90  ? 384 GLY C C   1 
ATOM 6452 O O   . GLY C 1 310 ? 133.055 136.352 148.832 1.00 56.45  ? 384 GLY C O   1 
ATOM 6453 N N   . ARG C 1 311 ? 131.138 137.510 148.634 1.00 48.69  ? 385 ARG C N   1 
ATOM 6454 C CA  . ARG C 1 311 ? 131.197 138.151 149.938 1.00 45.38  ? 385 ARG C CA  1 
ATOM 6455 C C   . ARG C 1 311 ? 129.985 137.716 150.754 1.00 48.45  ? 385 ARG C C   1 
ATOM 6456 O O   . ARG C 1 311 ? 129.281 136.769 150.394 1.00 55.70  ? 385 ARG C O   1 
ATOM 6457 C CB  . ARG C 1 311 ? 131.279 139.672 149.808 1.00 45.20  ? 385 ARG C CB  1 
ATOM 6458 C CG  . ARG C 1 311 ? 132.651 140.181 149.411 1.00 51.72  ? 385 ARG C CG  1 
ATOM 6459 C CD  . ARG C 1 311 ? 132.869 141.610 149.879 1.00 51.39  ? 385 ARG C CD  1 
ATOM 6460 N NE  . ARG C 1 311 ? 131.916 142.536 149.281 1.00 53.22  ? 385 ARG C NE  1 
ATOM 6461 C CZ  . ARG C 1 311 ? 131.749 143.793 149.669 1.00 53.97  ? 385 ARG C CZ  1 
ATOM 6462 N NH1 . ARG C 1 311 ? 132.452 144.308 150.664 1.00 54.81  ? 385 ARG C NH1 1 
ATOM 6463 N NH2 . ARG C 1 311 ? 130.856 144.552 149.042 1.00 50.23  ? 385 ARG C NH2 1 
ATOM 6464 N N   . LYS C 1 312 ? 129.779 138.402 151.879 1.00 48.33  ? 386 LYS C N   1 
ATOM 6465 C CA  . LYS C 1 312 ? 128.762 138.060 152.867 1.00 54.54  ? 386 LYS C CA  1 
ATOM 6466 C C   . LYS C 1 312 ? 127.467 137.567 152.231 1.00 58.53  ? 386 LYS C C   1 
ATOM 6467 O O   . LYS C 1 312 ? 126.918 138.198 151.323 1.00 63.92  ? 386 LYS C O   1 
ATOM 6468 C CB  . LYS C 1 312 ? 128.491 139.279 153.757 1.00 58.66  ? 386 LYS C CB  1 
ATOM 6469 C CG  . LYS C 1 312 ? 127.889 140.480 153.040 1.00 56.85  ? 386 LYS C CG  1 
ATOM 6470 C CD  . LYS C 1 312 ? 127.751 141.671 153.974 1.00 62.53  ? 386 LYS C CD  1 
ATOM 6471 C CE  . LYS C 1 312 ? 126.651 141.449 154.999 1.00 64.44  ? 386 LYS C CE  1 
ATOM 6472 N NZ  . LYS C 1 312 ? 126.439 142.647 155.858 1.00 61.38  ? 386 LYS C NZ  1 
ATOM 6473 N N   . ARG C 1 313 ? 127.005 136.411 152.697 1.00 46.03  ? 387 ARG C N   1 
ATOM 6474 C CA  . ARG C 1 313 ? 125.762 135.807 152.249 1.00 32.71  ? 387 ARG C CA  1 
ATOM 6475 C C   . ARG C 1 313 ? 124.696 135.990 153.317 1.00 39.88  ? 387 ARG C C   1 
ATOM 6476 O O   . ARG C 1 313 ? 124.948 135.760 154.504 1.00 53.28  ? 387 ARG C O   1 
ATOM 6477 C CB  . ARG C 1 313 ? 125.936 134.319 151.962 1.00 34.09  ? 387 ARG C CB  1 
ATOM 6478 C CG  . ARG C 1 313 ? 127.160 133.971 151.159 1.00 38.49  ? 387 ARG C CG  1 
ATOM 6479 C CD  . ARG C 1 313 ? 127.381 132.476 151.192 1.00 41.39  ? 387 ARG C CD  1 
ATOM 6480 N NE  . ARG C 1 313 ? 126.302 131.767 150.518 1.00 41.84  ? 387 ARG C NE  1 
ATOM 6481 C CZ  . ARG C 1 313 ? 126.251 130.452 150.367 1.00 45.21  ? 387 ARG C CZ  1 
ATOM 6482 N NH1 . ARG C 1 313 ? 127.191 129.662 150.859 1.00 48.33  ? 387 ARG C NH1 1 
ATOM 6483 N NH2 . ARG C 1 313 ? 125.234 129.916 149.701 1.00 41.71  ? 387 ARG C NH2 1 
ATOM 6484 N N   . GLN C 1 314 ? 123.508 136.401 152.893 1.00 38.12  ? 388 GLN C N   1 
ATOM 6485 C CA  . GLN C 1 314 ? 122.392 136.588 153.803 1.00 49.39  ? 388 GLN C CA  1 
ATOM 6486 C C   . GLN C 1 314 ? 121.144 135.984 153.183 1.00 58.19  ? 388 GLN C C   1 
ATOM 6487 O O   . GLN C 1 314 ? 120.866 136.192 151.999 1.00 62.36  ? 388 GLN C O   1 
ATOM 6488 C CB  . GLN C 1 314 ? 122.179 138.072 154.125 1.00 51.35  ? 388 GLN C CB  1 
ATOM 6489 C CG  . GLN C 1 314 ? 122.136 138.977 152.911 1.00 50.63  ? 388 GLN C CG  1 
ATOM 6490 C CD  . GLN C 1 314 ? 122.176 140.443 153.281 1.00 51.50  ? 388 GLN C CD  1 
ATOM 6491 O OE1 . GLN C 1 314 ? 123.228 141.078 153.229 1.00 53.50  ? 388 GLN C OE1 1 
ATOM 6492 N NE2 . GLN C 1 314 ? 121.028 140.989 153.659 1.00 58.38  ? 388 GLN C NE2 1 
ATOM 6493 N N   . GLU C 1 315 ? 120.404 135.227 153.985 1.00 54.17  ? 389 GLU C N   1 
ATOM 6494 C CA  . GLU C 1 315 ? 119.215 134.559 153.482 1.00 54.53  ? 389 GLU C CA  1 
ATOM 6495 C C   . GLU C 1 315 ? 118.105 135.569 153.233 1.00 56.85  ? 389 GLU C C   1 
ATOM 6496 O O   . GLU C 1 315 ? 117.903 136.503 154.014 1.00 57.95  ? 389 GLU C O   1 
ATOM 6497 C CB  . GLU C 1 315 ? 118.748 133.491 154.468 1.00 56.91  ? 389 GLU C CB  1 
ATOM 6498 C CG  . GLU C 1 315 ? 118.554 133.994 155.889 1.00 63.23  ? 389 GLU C CG  1 
ATOM 6499 C CD  . GLU C 1 315 ? 118.207 132.883 156.859 1.00 67.41  ? 389 GLU C CD  1 
ATOM 6500 O OE1 . GLU C 1 315 ? 117.930 131.755 156.399 1.00 67.20  ? 389 GLU C OE1 1 
ATOM 6501 O OE2 . GLU C 1 315 ? 118.208 133.138 158.082 1.00 66.80  ? 389 GLU C OE2 1 
ATOM 6502 N N   . ILE C 1 316 ? 117.390 135.385 152.128 1.00 49.98  ? 390 ILE C N   1 
ATOM 6503 C CA  . ILE C 1 316 ? 116.236 136.205 151.789 1.00 50.38  ? 390 ILE C CA  1 
ATOM 6504 C C   . ILE C 1 316 ? 114.988 135.341 151.902 1.00 65.12  ? 390 ILE C C   1 
ATOM 6505 O O   . ILE C 1 316 ? 114.910 134.259 151.307 1.00 68.02  ? 390 ILE C O   1 
ATOM 6506 C CB  . ILE C 1 316 ? 116.376 136.840 150.392 1.00 50.58  ? 390 ILE C CB  1 
ATOM 6507 C CG1 . ILE C 1 316 ? 116.513 135.779 149.299 1.00 56.24  ? 390 ILE C CG1 1 
ATOM 6508 C CG2 . ILE C 1 316 ? 117.563 137.789 150.359 1.00 60.07  ? 390 ILE C CG2 1 
ATOM 6509 C CD1 . ILE C 1 316 ? 116.423 136.338 147.900 1.00 60.56  ? 390 ILE C CD1 1 
ATOM 6510 N N   . ARG C 1 317 ? 114.037 135.797 152.707 1.00 65.96  ? 391 ARG C N   1 
ATOM 6511 C CA  . ARG C 1 317 ? 112.780 135.110 152.939 1.00 54.96  ? 391 ARG C CA  1 
ATOM 6512 C C   . ARG C 1 317 ? 111.670 135.797 152.147 1.00 62.14  ? 391 ARG C C   1 
ATOM 6513 O O   . ARG C 1 317 ? 111.925 136.645 151.286 1.00 66.38  ? 391 ARG C O   1 
ATOM 6514 C CB  . ARG C 1 317 ? 112.495 135.045 154.439 1.00 50.26  ? 391 ARG C CB  1 
ATOM 6515 C CG  . ARG C 1 317 ? 112.544 136.383 155.145 1.00 56.10  ? 391 ARG C CG  1 
ATOM 6516 C CD  . ARG C 1 317 ? 112.519 136.193 156.650 1.00 58.44  ? 391 ARG C CD  1 
ATOM 6517 N NE  . ARG C 1 317 ? 113.608 135.333 157.099 1.00 55.52  ? 391 ARG C NE  1 
ATOM 6518 C CZ  . ARG C 1 317 ? 114.821 135.764 157.416 1.00 58.51  ? 391 ARG C CZ  1 
ATOM 6519 N NH1 . ARG C 1 317 ? 115.139 137.046 157.349 1.00 56.06  ? 391 ARG C NH1 1 
ATOM 6520 N NH2 . ARG C 1 317 ? 115.739 134.886 157.809 1.00 61.04  ? 391 ARG C NH2 1 
ATOM 6521 N N   . HIS C 1 318 ? 110.421 135.414 152.425 1.00 65.30  ? 392 HIS C N   1 
ATOM 6522 C CA  . HIS C 1 318 ? 109.295 135.869 151.617 1.00 66.74  ? 392 HIS C CA  1 
ATOM 6523 C C   . HIS C 1 318 ? 109.186 137.388 151.574 1.00 69.10  ? 392 HIS C C   1 
ATOM 6524 O O   . HIS C 1 318 ? 108.852 137.954 150.528 1.00 77.36  ? 392 HIS C O   1 
ATOM 6525 C CB  . HIS C 1 318 ? 107.998 135.268 152.151 1.00 68.74  ? 392 HIS C CB  1 
ATOM 6526 C CG  . HIS C 1 318 ? 107.892 133.790 151.948 1.00 74.37  ? 392 HIS C CG  1 
ATOM 6527 N ND1 . HIS C 1 318 ? 106.892 133.031 152.517 1.00 76.95  ? 392 HIS C ND1 1 
ATOM 6528 C CD2 . HIS C 1 318 ? 108.659 132.930 151.238 1.00 77.32  ? 392 HIS C CD2 1 
ATOM 6529 C CE1 . HIS C 1 318 ? 107.049 131.767 152.167 1.00 76.80  ? 392 HIS C CE1 1 
ATOM 6530 N NE2 . HIS C 1 318 ? 108.114 131.679 151.391 1.00 78.13  ? 392 HIS C NE2 1 
ATOM 6531 N N   . GLY C 1 319 ? 109.461 138.064 152.685 1.00 55.37  ? 393 GLY C N   1 
ATOM 6532 C CA  . GLY C 1 319 ? 109.310 139.504 152.736 1.00 56.26  ? 393 GLY C CA  1 
ATOM 6533 C C   . GLY C 1 319 ? 110.485 140.314 152.243 1.00 56.40  ? 393 GLY C C   1 
ATOM 6534 O O   . GLY C 1 319 ? 110.411 141.545 152.226 1.00 58.08  ? 393 GLY C O   1 
ATOM 6535 N N   . ASP C 1 320 ? 111.569 139.664 151.836 1.00 57.81  ? 394 ASP C N   1 
ATOM 6536 C CA  . ASP C 1 320 ? 112.776 140.365 151.428 1.00 54.21  ? 394 ASP C CA  1 
ATOM 6537 C C   . ASP C 1 320 ? 112.823 140.517 149.915 1.00 57.60  ? 394 ASP C C   1 
ATOM 6538 O O   . ASP C 1 320 ? 112.475 139.595 149.173 1.00 65.07  ? 394 ASP C O   1 
ATOM 6539 C CB  . ASP C 1 320 ? 114.018 139.620 151.916 1.00 59.97  ? 394 ASP C CB  1 
ATOM 6540 C CG  . ASP C 1 320 ? 113.993 139.366 153.409 1.00 64.99  ? 394 ASP C CG  1 
ATOM 6541 O OD1 . ASP C 1 320 ? 113.234 140.062 154.116 1.00 65.49  ? 394 ASP C OD1 1 
ATOM 6542 O OD2 . ASP C 1 320 ? 114.731 138.473 153.874 1.00 67.72  ? 394 ASP C OD2 1 
ATOM 6543 N N   . SER C 1 321 ? 113.259 141.690 149.463 1.00 48.83  ? 395 SER C N   1 
ATOM 6544 C CA  . SER C 1 321 ? 113.395 141.982 148.047 1.00 51.43  ? 395 SER C CA  1 
ATOM 6545 C C   . SER C 1 321 ? 114.748 142.625 147.787 1.00 51.47  ? 395 SER C C   1 
ATOM 6546 O O   . SER C 1 321 ? 115.263 143.381 148.614 1.00 53.05  ? 395 SER C O   1 
ATOM 6547 C CB  . SER C 1 321 ? 112.279 142.906 147.551 1.00 56.63  ? 395 SER C CB  1 
ATOM 6548 O OG  . SER C 1 321 ? 112.426 143.174 146.169 1.00 59.15  ? 395 SER C OG  1 
ATOM 6549 N N   . ILE C 1 322 ? 115.318 142.318 146.625 1.00 47.90  ? 396 ILE C N   1 
ATOM 6550 C CA  . ILE C 1 322 ? 116.615 142.839 146.214 1.00 45.48  ? 396 ILE C CA  1 
ATOM 6551 C C   . ILE C 1 322 ? 116.426 143.627 144.924 1.00 46.94  ? 396 ILE C C   1 
ATOM 6552 O O   . ILE C 1 322 ? 115.765 143.157 143.991 1.00 52.88  ? 396 ILE C O   1 
ATOM 6553 C CB  . ILE C 1 322 ? 117.655 141.709 146.060 1.00 38.53  ? 396 ILE C CB  1 
ATOM 6554 C CG1 . ILE C 1 322 ? 119.055 142.274 145.852 1.00 53.18  ? 396 ILE C CG1 1 
ATOM 6555 C CG2 . ILE C 1 322 ? 117.305 140.753 144.946 1.00 43.94  ? 396 ILE C CG2 1 
ATOM 6556 C CD1 . ILE C 1 322 ? 120.133 141.232 146.004 1.00 54.74  ? 396 ILE C CD1 1 
ATOM 6557 N N   . SER C 1 323 ? 116.964 144.844 144.892 1.00 46.69  ? 397 SER C N   1 
ATOM 6558 C CA  . SER C 1 323 ? 116.833 145.740 143.750 1.00 49.14  ? 397 SER C CA  1 
ATOM 6559 C C   . SER C 1 323 ? 118.207 146.003 143.155 1.00 52.97  ? 397 SER C C   1 
ATOM 6560 O O   . SER C 1 323 ? 119.159 146.293 143.887 1.00 55.77  ? 397 SER C O   1 
ATOM 6561 C CB  . SER C 1 323 ? 116.171 147.058 144.153 1.00 55.52  ? 397 SER C CB  1 
ATOM 6562 O OG  . SER C 1 323 ? 116.932 147.727 145.142 1.00 62.45  ? 397 SER C OG  1 
ATOM 6563 N N   . ILE C 1 324 ? 118.306 145.909 141.831 1.00 47.17  ? 398 ILE C N   1 
ATOM 6564 C CA  . ILE C 1 324 ? 119.572 146.010 141.115 1.00 41.43  ? 398 ILE C CA  1 
ATOM 6565 C C   . ILE C 1 324 ? 119.459 147.114 140.074 1.00 46.95  ? 398 ILE C C   1 
ATOM 6566 O O   . ILE C 1 324 ? 118.483 147.162 139.317 1.00 54.14  ? 398 ILE C O   1 
ATOM 6567 C CB  . ILE C 1 324 ? 119.955 144.674 140.456 1.00 39.69  ? 398 ILE C CB  1 
ATOM 6568 C CG1 . ILE C 1 324 ? 119.788 143.527 141.451 1.00 49.62  ? 398 ILE C CG1 1 
ATOM 6569 C CG2 . ILE C 1 324 ? 121.379 144.726 139.947 1.00 54.36  ? 398 ILE C CG2 1 
ATOM 6570 C CD1 . ILE C 1 324 ? 120.019 142.166 140.855 1.00 50.82  ? 398 ILE C CD1 1 
ATOM 6571 N N   . THR C 1 325 ? 120.454 147.997 140.042 1.00 48.92  ? 399 THR C N   1 
ATOM 6572 C CA  . THR C 1 325 ? 120.477 149.124 139.122 1.00 51.30  ? 399 THR C CA  1 
ATOM 6573 C C   . THR C 1 325 ? 121.928 149.484 138.840 1.00 47.59  ? 399 THR C C   1 
ATOM 6574 O O   . THR C 1 325 ? 122.774 149.397 139.733 1.00 50.55  ? 399 THR C O   1 
ATOM 6575 C CB  . THR C 1 325 ? 119.727 150.331 139.703 1.00 58.82  ? 399 THR C CB  1 
ATOM 6576 O OG1 . THR C 1 325 ? 118.366 149.969 139.968 1.00 60.44  ? 399 THR C OG1 1 
ATOM 6577 C CG2 . THR C 1 325 ? 119.745 151.505 138.736 1.00 57.36  ? 399 THR C CG2 1 
ATOM 6578 N N   . THR C 1 326 ? 122.211 149.878 137.599 1.00 45.09  ? 400 THR C N   1 
ATOM 6579 C CA  . THR C 1 326 ? 123.570 150.253 137.229 1.00 49.23  ? 400 THR C CA  1 
ATOM 6580 C C   . THR C 1 326 ? 124.028 151.458 138.040 1.00 56.41  ? 400 THR C C   1 
ATOM 6581 O O   . THR C 1 326 ? 123.312 152.457 138.152 1.00 56.70  ? 400 THR C O   1 
ATOM 6582 C CB  . THR C 1 326 ? 123.649 150.559 135.734 1.00 42.91  ? 400 THR C CB  1 
ATOM 6583 O OG1 . THR C 1 326 ? 123.273 149.398 134.986 1.00 49.98  ? 400 THR C OG1 1 
ATOM 6584 C CG2 . THR C 1 326 ? 125.061 150.960 135.345 1.00 43.96  ? 400 THR C CG2 1 
ATOM 6585 N N   . SER C 1 327 ? 125.227 151.358 138.607 1.00 57.54  ? 401 SER C N   1 
ATOM 6586 C CA  . SER C 1 327 ? 125.754 152.409 139.460 1.00 50.30  ? 401 SER C CA  1 
ATOM 6587 C C   . SER C 1 327 ? 126.181 153.619 138.636 1.00 53.03  ? 401 SER C C   1 
ATOM 6588 O O   . SER C 1 327 ? 126.478 153.526 137.442 1.00 53.56  ? 401 SER C O   1 
ATOM 6589 C CB  . SER C 1 327 ? 126.940 151.894 140.273 1.00 53.56  ? 401 SER C CB  1 
ATOM 6590 O OG  . SER C 1 327 ? 127.482 152.917 141.090 1.00 59.39  ? 401 SER C OG  1 
ATOM 6591 N N   . THR C 1 328 ? 126.209 154.772 139.299 1.00 61.78  ? 402 THR C N   1 
ATOM 6592 C CA  . THR C 1 328 ? 126.716 156.004 138.715 1.00 60.89  ? 402 THR C CA  1 
ATOM 6593 C C   . THR C 1 328 ? 128.193 156.224 139.014 1.00 61.14  ? 402 THR C C   1 
ATOM 6594 O O   . THR C 1 328 ? 128.744 157.260 138.631 1.00 59.92  ? 402 THR C O   1 
ATOM 6595 C CB  . THR C 1 328 ? 125.904 157.201 139.217 1.00 66.10  ? 402 THR C CB  1 
ATOM 6596 O OG1 . THR C 1 328 ? 125.986 157.269 140.645 1.00 64.82  ? 402 THR C OG1 1 
ATOM 6597 C CG2 . THR C 1 328 ? 124.446 157.066 138.804 1.00 64.05  ? 402 THR C CG2 1 
ATOM 6598 N N   . TYR C 1 329 ? 128.841 155.271 139.687 1.00 61.94  ? 403 TYR C N   1 
ATOM 6599 C CA  . TYR C 1 329 ? 130.251 155.362 140.063 1.00 60.79  ? 403 TYR C CA  1 
ATOM 6600 C C   . TYR C 1 329 ? 130.991 154.184 139.445 1.00 66.72  ? 403 TYR C C   1 
ATOM 6601 O O   . TYR C 1 329 ? 131.120 153.120 140.071 1.00 68.60  ? 403 TYR C O   1 
ATOM 6602 C CB  . TYR C 1 329 ? 130.413 155.377 141.581 1.00 56.70  ? 403 TYR C CB  1 
ATOM 6603 C CG  . TYR C 1 329 ? 129.650 156.484 142.269 1.00 58.97  ? 403 TYR C CG  1 
ATOM 6604 C CD1 . TYR C 1 329 ? 130.153 157.777 142.312 1.00 64.39  ? 403 TYR C CD1 1 
ATOM 6605 C CD2 . TYR C 1 329 ? 128.429 156.237 142.877 1.00 63.17  ? 403 TYR C CD2 1 
ATOM 6606 C CE1 . TYR C 1 329 ? 129.460 158.793 142.941 1.00 65.43  ? 403 TYR C CE1 1 
ATOM 6607 C CE2 . TYR C 1 329 ? 127.728 157.246 143.508 1.00 68.28  ? 403 TYR C CE2 1 
ATOM 6608 C CZ  . TYR C 1 329 ? 128.248 158.522 143.537 1.00 67.00  ? 403 TYR C CZ  1 
ATOM 6609 O OH  . TYR C 1 329 ? 127.552 159.530 144.164 1.00 64.05  ? 403 TYR C OH  1 
ATOM 6610 N N   . PRO C 1 330 ? 131.494 154.326 138.222 1.00 55.84  ? 404 PRO C N   1 
ATOM 6611 C CA  . PRO C 1 330 ? 132.190 153.212 137.572 1.00 52.16  ? 404 PRO C CA  1 
ATOM 6612 C C   . PRO C 1 330 ? 133.581 153.005 138.149 1.00 59.62  ? 404 PRO C C   1 
ATOM 6613 O O   . PRO C 1 330 ? 134.113 153.825 138.899 1.00 62.96  ? 404 PRO C O   1 
ATOM 6614 C CB  . PRO C 1 330 ? 132.249 153.645 136.107 1.00 49.93  ? 404 PRO C CB  1 
ATOM 6615 C CG  . PRO C 1 330 ? 132.253 155.129 136.169 1.00 48.59  ? 404 PRO C CG  1 
ATOM 6616 C CD  . PRO C 1 330 ? 131.391 155.503 137.343 1.00 49.81  ? 404 PRO C CD  1 
ATOM 6617 N N   . LEU C 1 331 ? 134.174 151.868 137.780 1.00 60.67  ? 405 LEU C N   1 
ATOM 6618 C CA  . LEU C 1 331 ? 135.517 151.519 138.215 1.00 52.57  ? 405 LEU C CA  1 
ATOM 6619 C C   . LEU C 1 331 ? 136.481 151.699 137.055 1.00 61.02  ? 405 LEU C C   1 
ATOM 6620 O O   . LEU C 1 331 ? 136.456 150.892 136.113 1.00 67.98  ? 405 LEU C O   1 
ATOM 6621 C CB  . LEU C 1 331 ? 135.559 150.081 138.725 1.00 52.78  ? 405 LEU C CB  1 
ATOM 6622 C CG  . LEU C 1 331 ? 136.862 149.585 139.352 1.00 58.63  ? 405 LEU C CG  1 
ATOM 6623 C CD1 . LEU C 1 331 ? 136.562 148.696 140.545 1.00 59.86  ? 405 LEU C CD1 1 
ATOM 6624 C CD2 . LEU C 1 331 ? 137.704 148.832 138.337 1.00 59.56  ? 405 LEU C CD2 1 
ATOM 6625 N N   . PRO C 1 332 ? 137.336 152.721 137.063 1.00 56.26  ? 406 PRO C N   1 
ATOM 6626 C CA  . PRO C 1 332 ? 138.282 152.901 135.954 1.00 53.22  ? 406 PRO C CA  1 
ATOM 6627 C C   . PRO C 1 332 ? 139.507 152.013 136.127 1.00 56.44  ? 406 PRO C C   1 
ATOM 6628 O O   . PRO C 1 332 ? 140.238 152.123 137.113 1.00 58.44  ? 406 PRO C O   1 
ATOM 6629 C CB  . PRO C 1 332 ? 138.646 154.387 136.037 1.00 52.32  ? 406 PRO C CB  1 
ATOM 6630 C CG  . PRO C 1 332 ? 138.454 154.736 137.464 1.00 49.15  ? 406 PRO C CG  1 
ATOM 6631 C CD  . PRO C 1 332 ? 137.358 153.856 138.002 1.00 55.22  ? 406 PRO C CD  1 
ATOM 6632 N N   . SER C 1 333 ? 139.722 151.126 135.159 1.00 63.74  ? 407 SER C N   1 
ATOM 6633 C CA  . SER C 1 333 ? 140.872 150.233 135.141 1.00 65.16  ? 407 SER C CA  1 
ATOM 6634 C C   . SER C 1 333 ? 141.752 150.578 133.950 1.00 70.48  ? 407 SER C C   1 
ATOM 6635 O O   . SER C 1 333 ? 141.265 150.672 132.819 1.00 73.16  ? 407 SER C O   1 
ATOM 6636 C CB  . SER C 1 333 ? 140.437 148.768 135.073 1.00 69.22  ? 407 SER C CB  1 
ATOM 6637 O OG  . SER C 1 333 ? 141.559 147.904 135.089 1.00 66.34  ? 407 SER C OG  1 
ATOM 6638 N N   . ILE C 1 334 ? 143.043 150.761 134.206 1.00 72.91  ? 408 ILE C N   1 
ATOM 6639 C CA  . ILE C 1 334 ? 143.985 151.178 133.175 1.00 73.21  ? 408 ILE C CA  1 
ATOM 6640 C C   . ILE C 1 334 ? 144.422 149.967 132.364 1.00 74.44  ? 408 ILE C C   1 
ATOM 6641 O O   . ILE C 1 334 ? 144.709 148.900 132.919 1.00 79.76  ? 408 ILE C O   1 
ATOM 6642 C CB  . ILE C 1 334 ? 145.191 151.889 133.813 1.00 74.59  ? 408 ILE C CB  1 
ATOM 6643 C CG1 . ILE C 1 334 ? 144.728 153.111 134.604 1.00 77.01  ? 408 ILE C CG1 1 
ATOM 6644 C CG2 . ILE C 1 334 ? 146.195 152.299 132.754 1.00 76.20  ? 408 ILE C CG2 1 
ATOM 6645 C CD1 . ILE C 1 334 ? 145.845 153.833 135.314 1.00 75.58  ? 408 ILE C CD1 1 
ATOM 6646 N N   . CYS C 1 335 ? 144.472 150.126 131.045 1.00 75.80  ? 409 CYS C N   1 
ATOM 6647 C CA  . CYS C 1 335 ? 144.925 149.075 130.148 1.00 77.51  ? 409 CYS C CA  1 
ATOM 6648 C C   . CYS C 1 335 ? 146.311 149.392 129.598 1.00 78.37  ? 409 CYS C C   1 
ATOM 6649 O O   . CYS C 1 335 ? 146.702 150.553 129.456 1.00 81.20  ? 409 CYS C O   1 
ATOM 6650 C CB  . CYS C 1 335 ? 143.939 148.878 128.995 1.00 82.73  ? 409 CYS C CB  1 
ATOM 6651 S SG  . CYS C 1 335 ? 142.256 148.507 129.523 1.00 92.79  ? 409 CYS C SG  1 
ATOM 6652 N N   . VAL C 1 336 ? 147.052 148.332 129.287 1.00 82.62  ? 410 VAL C N   1 
ATOM 6653 C CA  . VAL C 1 336 ? 148.431 148.474 128.830 1.00 85.07  ? 410 VAL C CA  1 
ATOM 6654 C C   . VAL C 1 336 ? 148.508 149.022 127.410 1.00 89.42  ? 410 VAL C C   1 
ATOM 6655 O O   . VAL C 1 336 ? 149.328 149.897 127.125 1.00 91.54  ? 410 VAL C O   1 
ATOM 6656 C CB  . VAL C 1 336 ? 149.169 147.127 128.966 1.00 86.30  ? 410 VAL C CB  1 
ATOM 6657 C CG1 . VAL C 1 336 ? 149.269 146.744 130.421 1.00 87.02  ? 410 VAL C CG1 1 
ATOM 6658 C CG2 . VAL C 1 336 ? 148.441 146.030 128.212 1.00 86.90  ? 410 VAL C CG2 1 
ATOM 6659 N N   . ARG C 1 337 ? 147.670 148.533 126.496 1.00 89.36  ? 411 ARG C N   1 
ATOM 6660 C CA  . ARG C 1 337 ? 147.706 148.982 125.109 1.00 85.76  ? 411 ARG C CA  1 
ATOM 6661 C C   . ARG C 1 337 ? 146.437 149.721 124.711 1.00 87.41  ? 411 ARG C C   1 
ATOM 6662 O O   . ARG C 1 337 ? 146.514 150.876 124.282 1.00 91.11  ? 411 ARG C O   1 
ATOM 6663 C CB  . ARG C 1 337 ? 147.954 147.789 124.175 1.00 84.39  ? 411 ARG C CB  1 
ATOM 6664 C CG  . ARG C 1 337 ? 148.861 146.726 124.764 1.00 86.94  ? 411 ARG C CG  1 
ATOM 6665 C CD  . ARG C 1 337 ? 149.258 145.689 123.730 1.00 90.00  ? 411 ARG C CD  1 
ATOM 6666 N NE  . ARG C 1 337 ? 148.110 144.948 123.220 1.00 92.21  ? 411 ARG C NE  1 
ATOM 6667 C CZ  . ARG C 1 337 ? 147.708 143.778 123.695 1.00 92.35  ? 411 ARG C CZ  1 
ATOM 6668 N NH1 . ARG C 1 337 ? 148.334 143.187 124.699 1.00 90.90  ? 411 ARG C NH1 1 
ATOM 6669 N NH2 . ARG C 1 337 ? 146.652 143.184 123.147 1.00 91.84  ? 411 ARG C NH2 1 
ATOM 6670 N N   . ASP C 1 338 ? 145.272 149.098 124.848 1.00 88.14  ? 412 ASP C N   1 
ATOM 6671 C CA  . ASP C 1 338 ? 144.016 149.709 124.441 1.00 88.75  ? 412 ASP C CA  1 
ATOM 6672 C C   . ASP C 1 338 ? 142.876 148.956 125.110 1.00 88.87  ? 412 ASP C C   1 
ATOM 6673 O O   . ASP C 1 338 ? 143.064 147.824 125.571 1.00 89.26  ? 412 ASP C O   1 
ATOM 6674 C CB  . ASP C 1 338 ? 143.864 149.703 122.908 1.00 90.76  ? 412 ASP C CB  1 
ATOM 6675 C CG  . ASP C 1 338 ? 143.889 148.306 122.316 1.00 95.06  ? 412 ASP C CG  1 
ATOM 6676 O OD1 . ASP C 1 338 ? 144.093 147.333 123.070 1.00 98.20  ? 412 ASP C OD1 1 
ATOM 6677 O OD2 . ASP C 1 338 ? 143.705 148.182 121.087 1.00 92.37  ? 412 ASP C OD2 1 
ATOM 6678 N N   . PRO C 1 339 ? 141.691 149.563 125.200 1.00 84.77  ? 413 PRO C N   1 
ATOM 6679 C CA  . PRO C 1 339 ? 140.560 148.854 125.818 1.00 85.12  ? 413 PRO C CA  1 
ATOM 6680 C C   . PRO C 1 339 ? 140.163 147.583 125.091 1.00 84.65  ? 413 PRO C C   1 
ATOM 6681 O O   . PRO C 1 339 ? 139.583 146.683 125.710 1.00 82.50  ? 413 PRO C O   1 
ATOM 6682 C CB  . PRO C 1 339 ? 139.431 149.896 125.782 1.00 84.53  ? 413 PRO C CB  1 
ATOM 6683 C CG  . PRO C 1 339 ? 139.886 150.946 124.821 1.00 84.45  ? 413 PRO C CG  1 
ATOM 6684 C CD  . PRO C 1 339 ? 141.368 150.973 124.939 1.00 85.43  ? 413 PRO C CD  1 
ATOM 6685 N N   . VAL C 1 340 ? 140.458 147.477 123.797 1.00 91.33  ? 414 VAL C N   1 
ATOM 6686 C CA  . VAL C 1 340 ? 139.932 146.388 122.983 1.00 94.02  ? 414 VAL C CA  1 
ATOM 6687 C C   . VAL C 1 340 ? 140.882 145.199 122.950 1.00 96.25  ? 414 VAL C C   1 
ATOM 6688 O O   . VAL C 1 340 ? 140.538 144.106 123.415 1.00 94.87  ? 414 VAL C O   1 
ATOM 6689 C CB  . VAL C 1 340 ? 139.634 146.876 121.556 1.00 91.84  ? 414 VAL C CB  1 
ATOM 6690 C CG1 . VAL C 1 340 ? 139.233 145.709 120.693 1.00 89.58  ? 414 VAL C CG1 1 
ATOM 6691 C CG2 . VAL C 1 340 ? 138.540 147.927 121.577 1.00 90.89  ? 414 VAL C CG2 1 
ATOM 6692 N N   . SER C 1 341 ? 142.082 145.397 122.395 1.00 96.08  ? 415 SER C N   1 
ATOM 6693 C CA  . SER C 1 341 ? 143.001 144.280 122.204 1.00 93.34  ? 415 SER C CA  1 
ATOM 6694 C C   . SER C 1 341 ? 143.458 143.678 123.524 1.00 91.10  ? 415 SER C C   1 
ATOM 6695 O O   . SER C 1 341 ? 143.850 142.507 123.555 1.00 92.78  ? 415 SER C O   1 
ATOM 6696 C CB  . SER C 1 341 ? 144.212 144.721 121.381 1.00 95.60  ? 415 SER C CB  1 
ATOM 6697 O OG  . SER C 1 341 ? 145.129 145.454 122.175 1.00 99.35  ? 415 SER C OG  1 
ATOM 6698 N N   . ASP C 1 342 ? 143.423 144.451 124.610 1.00 88.21  ? 416 ASP C N   1 
ATOM 6699 C CA  . ASP C 1 342 ? 143.716 143.889 125.924 1.00 92.93  ? 416 ASP C CA  1 
ATOM 6700 C C   . ASP C 1 342 ? 142.679 142.844 126.314 1.00 92.12  ? 416 ASP C C   1 
ATOM 6701 O O   . ASP C 1 342 ? 143.021 141.799 126.879 1.00 90.71  ? 416 ASP C O   1 
ATOM 6702 C CB  . ASP C 1 342 ? 143.775 145.004 126.966 1.00 91.81  ? 416 ASP C CB  1 
ATOM 6703 C CG  . ASP C 1 342 ? 144.102 144.491 128.354 1.00 94.12  ? 416 ASP C CG  1 
ATOM 6704 O OD1 . ASP C 1 342 ? 144.746 143.427 128.467 1.00 95.67  ? 416 ASP C OD1 1 
ATOM 6705 O OD2 . ASP C 1 342 ? 143.702 145.152 129.335 1.00 95.15  ? 416 ASP C OD2 1 
ATOM 6706 N N   . TRP C 1 343 ? 141.404 143.112 126.024 1.00 80.69  ? 417 TRP C N   1 
ATOM 6707 C CA  . TRP C 1 343 ? 140.349 142.170 126.381 1.00 77.43  ? 417 TRP C CA  1 
ATOM 6708 C C   . TRP C 1 343 ? 140.443 140.887 125.568 1.00 78.02  ? 417 TRP C C   1 
ATOM 6709 O O   . TRP C 1 343 ? 140.269 139.789 126.111 1.00 80.10  ? 417 TRP C O   1 
ATOM 6710 C CB  . TRP C 1 343 ? 138.980 142.823 126.199 1.00 75.26  ? 417 TRP C CB  1 
ATOM 6711 C CG  . TRP C 1 343 ? 137.850 141.948 126.624 1.00 75.87  ? 417 TRP C CG  1 
ATOM 6712 C CD1 . TRP C 1 343 ? 137.536 141.581 127.895 1.00 75.68  ? 417 TRP C CD1 1 
ATOM 6713 C CD2 . TRP C 1 343 ? 136.862 141.352 125.778 1.00 77.24  ? 417 TRP C CD2 1 
ATOM 6714 N NE1 . TRP C 1 343 ? 136.425 140.777 127.895 1.00 75.23  ? 417 TRP C NE1 1 
ATOM 6715 C CE2 . TRP C 1 343 ? 135.990 140.624 126.606 1.00 75.88  ? 417 TRP C CE2 1 
ATOM 6716 C CE3 . TRP C 1 343 ? 136.635 141.359 124.400 1.00 76.56  ? 417 TRP C CE3 1 
ATOM 6717 C CZ2 . TRP C 1 343 ? 134.910 139.909 126.103 1.00 73.78  ? 417 TRP C CZ2 1 
ATOM 6718 C CZ3 . TRP C 1 343 ? 135.561 140.650 123.903 1.00 73.06  ? 417 TRP C CZ3 1 
ATOM 6719 C CH2 . TRP C 1 343 ? 134.712 139.935 124.752 1.00 70.76  ? 417 TRP C CH2 1 
ATOM 6720 N N   . PHE C 1 344 ? 140.712 140.999 124.267 1.00 89.29  ? 418 PHE C N   1 
ATOM 6721 C CA  . PHE C 1 344 ? 140.798 139.806 123.432 1.00 89.36  ? 418 PHE C CA  1 
ATOM 6722 C C   . PHE C 1 344 ? 142.021 138.972 123.787 1.00 90.19  ? 418 PHE C C   1 
ATOM 6723 O O   . PHE C 1 344 ? 141.968 137.738 123.753 1.00 90.46  ? 418 PHE C O   1 
ATOM 6724 C CB  . PHE C 1 344 ? 140.810 140.200 121.957 1.00 88.49  ? 418 PHE C CB  1 
ATOM 6725 C CG  . PHE C 1 344 ? 139.472 140.646 121.445 1.00 90.14  ? 418 PHE C CG  1 
ATOM 6726 C CD1 . PHE C 1 344 ? 138.519 139.718 121.065 1.00 90.29  ? 418 PHE C CD1 1 
ATOM 6727 C CD2 . PHE C 1 344 ? 139.161 141.991 121.359 1.00 90.97  ? 418 PHE C CD2 1 
ATOM 6728 C CE1 . PHE C 1 344 ? 137.285 140.123 120.600 1.00 90.75  ? 418 PHE C CE1 1 
ATOM 6729 C CE2 . PHE C 1 344 ? 137.927 142.401 120.894 1.00 91.08  ? 418 PHE C CE2 1 
ATOM 6730 C CZ  . PHE C 1 344 ? 136.989 141.466 120.515 1.00 89.99  ? 418 PHE C CZ  1 
ATOM 6731 N N   . GLU C 1 345 ? 143.133 139.627 124.127 1.00 88.60  ? 419 GLU C N   1 
ATOM 6732 C CA  . GLU C 1 345 ? 144.304 138.895 124.597 1.00 82.91  ? 419 GLU C CA  1 
ATOM 6733 C C   . GLU C 1 345 ? 144.008 138.178 125.906 1.00 83.49  ? 419 GLU C C   1 
ATOM 6734 O O   . GLU C 1 345 ? 144.492 137.064 126.138 1.00 87.26  ? 419 GLU C O   1 
ATOM 6735 C CB  . GLU C 1 345 ? 145.488 139.846 124.762 1.00 83.20  ? 419 GLU C CB  1 
ATOM 6736 C CG  . GLU C 1 345 ? 146.735 139.191 125.327 1.00 88.26  ? 419 GLU C CG  1 
ATOM 6737 C CD  . GLU C 1 345 ? 147.731 140.198 125.866 1.00 89.87  ? 419 GLU C CD  1 
ATOM 6738 O OE1 . GLU C 1 345 ? 147.358 141.380 126.021 1.00 88.32  ? 419 GLU C OE1 1 
ATOM 6739 O OE2 . GLU C 1 345 ? 148.886 139.807 126.135 1.00 91.47  ? 419 GLU C OE2 1 
ATOM 6740 N N   . SER C 1 346 ? 143.214 138.803 126.776 1.00 85.76  ? 420 SER C N   1 
ATOM 6741 C CA  . SER C 1 346 ? 142.853 138.169 128.038 1.00 88.23  ? 420 SER C CA  1 
ATOM 6742 C C   . SER C 1 346 ? 141.996 136.930 127.810 1.00 91.45  ? 420 SER C C   1 
ATOM 6743 O O   . SER C 1 346 ? 142.119 135.940 128.541 1.00 94.20  ? 420 SER C O   1 
ATOM 6744 C CB  . SER C 1 346 ? 142.125 139.167 128.936 1.00 90.92  ? 420 SER C CB  1 
ATOM 6745 O OG  . SER C 1 346 ? 141.923 138.624 130.227 1.00 95.22  ? 420 SER C OG  1 
ATOM 6746 N N   . LEU C 1 347 ? 141.115 136.971 126.809 1.00 85.91  ? 421 LEU C N   1 
ATOM 6747 C CA  . LEU C 1 347 ? 140.250 135.828 126.531 1.00 83.95  ? 421 LEU C CA  1 
ATOM 6748 C C   . LEU C 1 347 ? 141.063 134.602 126.136 1.00 84.75  ? 421 LEU C C   1 
ATOM 6749 O O   . LEU C 1 347 ? 140.801 133.489 126.606 1.00 86.66  ? 421 LEU C O   1 
ATOM 6750 C CB  . LEU C 1 347 ? 139.254 136.183 125.429 1.00 84.09  ? 421 LEU C CB  1 
ATOM 6751 C CG  . LEU C 1 347 ? 138.150 137.185 125.756 1.00 82.87  ? 421 LEU C CG  1 
ATOM 6752 C CD1 . LEU C 1 347 ? 137.406 137.573 124.493 1.00 83.77  ? 421 LEU C CD1 1 
ATOM 6753 C CD2 . LEU C 1 347 ? 137.196 136.595 126.769 1.00 85.32  ? 421 LEU C CD2 1 
ATOM 6754 N N   . ALA C 1 348 ? 142.056 134.787 125.266 1.00 90.94  ? 422 ALA C N   1 
ATOM 6755 C CA  . ALA C 1 348 ? 142.834 133.653 124.779 1.00 92.68  ? 422 ALA C CA  1 
ATOM 6756 C C   . ALA C 1 348 ? 143.782 133.128 125.850 1.00 93.95  ? 422 ALA C C   1 
ATOM 6757 O O   . ALA C 1 348 ? 143.900 131.914 126.047 1.00 94.87  ? 422 ALA C O   1 
ATOM 6758 C CB  . ALA C 1 348 ? 143.608 134.051 123.522 1.00 92.00  ? 422 ALA C CB  1 
ATOM 6759 N N   . GLN C 1 349 ? 144.466 134.031 126.554 1.00 102.03 ? 423 GLN C N   1 
ATOM 6760 C CA  . GLN C 1 349 ? 145.508 133.605 127.482 1.00 103.07 ? 423 GLN C CA  1 
ATOM 6761 C C   . GLN C 1 349 ? 144.929 132.999 128.754 1.00 103.46 ? 423 GLN C C   1 
ATOM 6762 O O   . GLN C 1 349 ? 145.542 132.100 129.342 1.00 103.53 ? 423 GLN C O   1 
ATOM 6763 C CB  . GLN C 1 349 ? 146.419 134.785 127.821 1.00 103.37 ? 423 GLN C CB  1 
ATOM 6764 C CG  . GLN C 1 349 ? 147.667 134.406 128.599 1.00 104.36 ? 423 GLN C CG  1 
ATOM 6765 C CD  . GLN C 1 349 ? 148.643 135.558 128.731 1.00 104.41 ? 423 GLN C CD  1 
ATOM 6766 O OE1 . GLN C 1 349 ? 148.415 136.643 128.197 1.00 103.93 ? 423 GLN C OE1 1 
ATOM 6767 N NE2 . GLN C 1 349 ? 149.737 135.328 129.447 1.00 103.19 ? 423 GLN C NE2 1 
ATOM 6768 N N   . CYS C 1 350 ? 143.761 133.463 129.193 1.00 103.83 ? 424 CYS C N   1 
ATOM 6769 C CA  . CYS C 1 350 ? 143.171 133.000 130.443 1.00 105.23 ? 424 CYS C CA  1 
ATOM 6770 C C   . CYS C 1 350 ? 142.032 132.008 130.235 1.00 105.36 ? 424 CYS C C   1 
ATOM 6771 O O   . CYS C 1 350 ? 142.069 130.901 130.781 1.00 104.95 ? 424 CYS C O   1 
ATOM 6772 C CB  . CYS C 1 350 ? 142.673 134.197 131.263 1.00 103.13 ? 424 CYS C CB  1 
ATOM 6773 S SG  . CYS C 1 350 ? 141.655 133.751 132.688 1.00 103.21 ? 424 CYS C SG  1 
ATOM 6774 N N   . LEU C 1 351 ? 141.019 132.380 129.456 1.00 103.09 ? 425 LEU C N   1 
ATOM 6775 C CA  . LEU C 1 351 ? 139.826 131.559 129.294 1.00 101.07 ? 425 LEU C CA  1 
ATOM 6776 C C   . LEU C 1 351 ? 139.878 130.654 128.069 1.00 101.67 ? 425 LEU C C   1 
ATOM 6777 O O   . LEU C 1 351 ? 138.960 129.849 127.878 1.00 102.35 ? 425 LEU C O   1 
ATOM 6778 C CB  . LEU C 1 351 ? 138.584 132.453 129.222 1.00 101.43 ? 425 LEU C CB  1 
ATOM 6779 C CG  . LEU C 1 351 ? 137.279 131.862 129.757 1.00 102.83 ? 425 LEU C CG  1 
ATOM 6780 C CD1 . LEU C 1 351 ? 137.497 131.222 131.118 1.00 100.54 ? 425 LEU C CD1 1 
ATOM 6781 C CD2 . LEU C 1 351 ? 136.199 132.930 129.832 1.00 101.44 ? 425 LEU C CD2 1 
ATOM 6782 N N   . HIS C 1 352 ? 140.921 130.762 127.244 1.00 106.69 ? 426 HIS C N   1 
ATOM 6783 C CA  . HIS C 1 352 ? 141.084 129.942 126.041 1.00 105.49 ? 426 HIS C CA  1 
ATOM 6784 C C   . HIS C 1 352 ? 139.887 130.102 125.100 1.00 105.33 ? 426 HIS C C   1 
ATOM 6785 O O   . HIS C 1 352 ? 139.153 129.156 124.809 1.00 106.75 ? 426 HIS C O   1 
ATOM 6786 C CB  . HIS C 1 352 ? 141.310 128.470 126.406 1.00 106.39 ? 426 HIS C CB  1 
ATOM 6787 C CG  . HIS C 1 352 ? 142.488 128.241 127.301 1.00 106.98 ? 426 HIS C CG  1 
ATOM 6788 N ND1 . HIS C 1 352 ? 142.682 127.062 127.988 1.00 107.22 ? 426 HIS C ND1 1 
ATOM 6789 C CD2 . HIS C 1 352 ? 143.535 129.039 127.620 1.00 105.85 ? 426 HIS C CD2 1 
ATOM 6790 C CE1 . HIS C 1 352 ? 143.797 127.144 128.693 1.00 105.41 ? 426 HIS C CE1 1 
ATOM 6791 N NE2 . HIS C 1 352 ? 144.334 128.333 128.487 1.00 104.43 ? 426 HIS C NE2 1 
ATOM 6792 N N   . TRP C 1 353 ? 139.704 131.336 124.625 1.00 103.09 ? 427 TRP C N   1 
ATOM 6793 C CA  . TRP C 1 353 ? 138.570 131.635 123.756 1.00 104.63 ? 427 TRP C CA  1 
ATOM 6794 C C   . TRP C 1 353 ? 138.779 131.103 122.343 1.00 104.17 ? 427 TRP C C   1 
ATOM 6795 O O   . TRP C 1 353 ? 137.805 130.865 121.622 1.00 103.02 ? 427 TRP C O   1 
ATOM 6796 C CB  . TRP C 1 353 ? 138.324 133.143 123.723 1.00 105.69 ? 427 TRP C CB  1 
ATOM 6797 C CG  . TRP C 1 353 ? 137.299 133.572 122.719 1.00 105.69 ? 427 TRP C CG  1 
ATOM 6798 C CD1 . TRP C 1 353 ? 136.050 133.053 122.549 1.00 103.79 ? 427 TRP C CD1 1 
ATOM 6799 C CD2 . TRP C 1 353 ? 137.444 134.597 121.730 1.00 103.73 ? 427 TRP C CD2 1 
ATOM 6800 N NE1 . TRP C 1 353 ? 135.403 133.699 121.525 1.00 102.14 ? 427 TRP C NE1 1 
ATOM 6801 C CE2 . TRP C 1 353 ? 136.239 134.650 121.004 1.00 102.37 ? 427 TRP C CE2 1 
ATOM 6802 C CE3 . TRP C 1 353 ? 138.475 135.478 121.391 1.00 102.75 ? 427 TRP C CE3 1 
ATOM 6803 C CZ2 . TRP C 1 353 ? 136.037 135.549 119.960 1.00 102.84 ? 427 TRP C CZ2 1 
ATOM 6804 C CZ3 . TRP C 1 353 ? 138.272 136.369 120.354 1.00 103.51 ? 427 TRP C CZ3 1 
ATOM 6805 C CH2 . TRP C 1 353 ? 137.062 136.398 119.652 1.00 102.91 ? 427 TRP C CH2 1 
ATOM 6806 N N   . ASN C 1 354 ? 140.028 130.916 121.923 1.00 113.01 ? 428 ASN C N   1 
ATOM 6807 C CA  . ASN C 1 354 ? 140.316 130.476 120.563 1.00 112.47 ? 428 ASN C CA  1 
ATOM 6808 C C   . ASN C 1 354 ? 140.759 129.022 120.485 1.00 112.51 ? 428 ASN C C   1 
ATOM 6809 O O   . ASN C 1 354 ? 140.242 128.268 119.655 1.00 113.55 ? 428 ASN C O   1 
ATOM 6810 C CB  . ASN C 1 354 ? 141.391 131.368 119.935 1.00 113.47 ? 428 ASN C CB  1 
ATOM 6811 C CG  . ASN C 1 354 ? 141.717 130.969 118.509 1.00 116.13 ? 428 ASN C CG  1 
ATOM 6812 O OD1 . ASN C 1 354 ? 140.948 131.236 117.585 1.00 115.77 ? 428 ASN C OD1 1 
ATOM 6813 N ND2 . ASN C 1 354 ? 142.864 130.325 118.322 1.00 114.62 ? 428 ASN C ND2 1 
ATOM 6814 N N   . VAL C 1 355 ? 141.702 128.610 121.325 1.00 113.24 ? 429 VAL C N   1 
ATOM 6815 C CA  . VAL C 1 355 ? 142.199 127.240 121.300 1.00 115.49 ? 429 VAL C CA  1 
ATOM 6816 C C   . VAL C 1 355 ? 141.160 126.289 121.880 1.00 113.09 ? 429 VAL C C   1 
ATOM 6817 O O   . VAL C 1 355 ? 140.483 125.571 121.144 1.00 111.87 ? 429 VAL C O   1 
ATOM 6818 C CB  . VAL C 1 355 ? 143.532 127.117 122.058 1.00 114.31 ? 429 VAL C CB  1 
ATOM 6819 C CG1 . VAL C 1 355 ? 144.527 128.151 121.554 1.00 112.51 ? 429 VAL C CG1 1 
ATOM 6820 C CG2 . VAL C 1 355 ? 143.307 127.269 123.554 1.00 109.09 ? 429 VAL C CG2 1 
ATOM 6821 N N   . SER D 1 21  ? 112.418 157.248 127.121 1.00 106.76 ? 95  SER D N   1 
ATOM 6822 C CA  . SER D 1 21  ? 111.603 156.630 126.082 1.00 110.27 ? 95  SER D CA  1 
ATOM 6823 C C   . SER D 1 21  ? 111.023 157.682 125.143 1.00 109.18 ? 95  SER D C   1 
ATOM 6824 O O   . SER D 1 21  ? 110.011 158.309 125.452 1.00 108.97 ? 95  SER D O   1 
ATOM 6825 C CB  . SER D 1 21  ? 110.476 155.804 126.705 1.00 108.78 ? 95  SER D CB  1 
ATOM 6826 O OG  . SER D 1 21  ? 109.667 155.207 125.706 1.00 104.52 ? 95  SER D OG  1 
ATOM 6827 N N   . VAL D 1 22  ? 111.676 157.873 123.997 1.00 116.18 ? 96  VAL D N   1 
ATOM 6828 C CA  . VAL D 1 22  ? 111.197 158.837 123.014 1.00 119.05 ? 96  VAL D CA  1 
ATOM 6829 C C   . VAL D 1 22  ? 109.872 158.355 122.441 1.00 120.51 ? 96  VAL D C   1 
ATOM 6830 O O   . VAL D 1 22  ? 109.702 157.167 122.136 1.00 120.07 ? 96  VAL D O   1 
ATOM 6831 C CB  . VAL D 1 22  ? 112.249 159.059 121.916 1.00 120.86 ? 96  VAL D CB  1 
ATOM 6832 C CG1 . VAL D 1 22  ? 113.507 159.673 122.510 1.00 120.20 ? 96  VAL D CG1 1 
ATOM 6833 C CG2 . VAL D 1 22  ? 112.586 157.750 121.214 1.00 118.63 ? 96  VAL D CG2 1 
ATOM 6834 N N   . ARG D 1 23  ? 108.911 159.271 122.319 1.00 119.14 ? 97  ARG D N   1 
ATOM 6835 C CA  . ARG D 1 23  ? 107.567 158.911 121.884 1.00 117.87 ? 97  ARG D CA  1 
ATOM 6836 C C   . ARG D 1 23  ? 107.374 159.077 120.380 1.00 116.82 ? 97  ARG D C   1 
ATOM 6837 O O   . ARG D 1 23  ? 107.188 158.088 119.666 1.00 117.22 ? 97  ARG D O   1 
ATOM 6838 C CB  . ARG D 1 23  ? 106.534 159.754 122.645 1.00 116.66 ? 97  ARG D CB  1 
ATOM 6839 C CG  . ARG D 1 23  ? 106.615 159.625 124.155 1.00 116.29 ? 97  ARG D CG  1 
ATOM 6840 C CD  . ARG D 1 23  ? 106.189 158.239 124.607 1.00 117.09 ? 97  ARG D CD  1 
ATOM 6841 N NE  . ARG D 1 23  ? 104.789 157.977 124.294 1.00 118.33 ? 97  ARG D NE  1 
ATOM 6842 C CZ  . ARG D 1 23  ? 104.154 156.850 124.583 1.00 117.32 ? 97  ARG D CZ  1 
ATOM 6843 N NH1 . ARG D 1 23  ? 104.765 155.849 125.195 1.00 114.98 ? 97  ARG D NH1 1 
ATOM 6844 N NH2 . ARG D 1 23  ? 102.873 156.723 124.249 1.00 117.63 ? 97  ARG D NH2 1 
ATOM 6845 N N   . LEU D 1 24  ? 107.467 160.306 119.878 1.00 117.49 ? 98  LEU D N   1 
ATOM 6846 C CA  . LEU D 1 24  ? 107.092 160.575 118.496 1.00 119.31 ? 98  LEU D CA  1 
ATOM 6847 C C   . LEU D 1 24  ? 107.390 162.032 118.174 1.00 119.42 ? 98  LEU D C   1 
ATOM 6848 O O   . LEU D 1 24  ? 107.403 162.885 119.066 1.00 119.13 ? 98  LEU D O   1 
ATOM 6849 C CB  . LEU D 1 24  ? 105.606 160.268 118.263 1.00 118.10 ? 98  LEU D CB  1 
ATOM 6850 C CG  . LEU D 1 24  ? 105.000 160.412 116.869 1.00 117.48 ? 98  LEU D CG  1 
ATOM 6851 C CD1 . LEU D 1 24  ? 105.670 159.462 115.891 1.00 116.53 ? 98  LEU D CD1 1 
ATOM 6852 C CD2 . LEU D 1 24  ? 103.507 160.146 116.944 1.00 116.14 ? 98  LEU D CD2 1 
ATOM 6853 N N   . THR D 1 25  ? 107.629 162.303 116.889 1.00 119.36 ? 99  THR D N   1 
ATOM 6854 C CA  . THR D 1 25  ? 107.820 163.672 116.407 1.00 118.80 ? 99  THR D CA  1 
ATOM 6855 C C   . THR D 1 25  ? 107.446 163.686 114.926 1.00 117.25 ? 99  THR D C   1 
ATOM 6856 O O   . THR D 1 25  ? 108.236 163.253 114.082 1.00 116.20 ? 99  THR D O   1 
ATOM 6857 C CB  . THR D 1 25  ? 109.250 164.149 116.625 1.00 118.77 ? 99  THR D CB  1 
ATOM 6858 O OG1 . THR D 1 25  ? 109.585 164.057 118.016 1.00 117.68 ? 99  THR D OG1 1 
ATOM 6859 C CG2 . THR D 1 25  ? 109.403 165.593 116.174 1.00 117.07 ? 99  THR D CG2 1 
ATOM 6860 N N   . TRP D 1 26  ? 106.245 164.182 114.621 1.00 108.17 ? 100 TRP D N   1 
ATOM 6861 C CA  . TRP D 1 26  ? 105.779 164.230 113.240 1.00 106.93 ? 100 TRP D CA  1 
ATOM 6862 C C   . TRP D 1 26  ? 106.151 165.517 112.520 1.00 106.35 ? 100 TRP D C   1 
ATOM 6863 O O   . TRP D 1 26  ? 106.258 165.511 111.287 1.00 105.53 ? 100 TRP D O   1 
ATOM 6864 C CB  . TRP D 1 26  ? 104.257 164.059 113.174 1.00 103.75 ? 100 TRP D CB  1 
ATOM 6865 C CG  . TRP D 1 26  ? 103.787 162.640 113.243 1.00 104.21 ? 100 TRP D CG  1 
ATOM 6866 C CD1 . TRP D 1 26  ? 102.897 162.117 114.130 1.00 103.81 ? 100 TRP D CD1 1 
ATOM 6867 C CD2 . TRP D 1 26  ? 104.187 161.558 112.392 1.00 105.54 ? 100 TRP D CD2 1 
ATOM 6868 N NE1 . TRP D 1 26  ? 102.710 160.780 113.882 1.00 102.32 ? 100 TRP D NE1 1 
ATOM 6869 C CE2 . TRP D 1 26  ? 103.494 160.412 112.822 1.00 105.02 ? 100 TRP D CE2 1 
ATOM 6870 C CE3 . TRP D 1 26  ? 105.062 161.448 111.307 1.00 106.02 ? 100 TRP D CE3 1 
ATOM 6871 C CZ2 . TRP D 1 26  ? 103.648 159.171 112.209 1.00 106.44 ? 100 TRP D CZ2 1 
ATOM 6872 C CZ3 . TRP D 1 26  ? 105.214 160.216 110.700 1.00 104.71 ? 100 TRP D CZ3 1 
ATOM 6873 C CH2 . TRP D 1 26  ? 104.511 159.095 111.152 1.00 104.10 ? 100 TRP D CH2 1 
ATOM 6874 N N   . ASN D 1 27  ? 106.324 166.620 113.254 1.00 111.51 ? 101 ASN D N   1 
ATOM 6875 C CA  . ASN D 1 27  ? 106.559 167.940 112.674 1.00 111.78 ? 101 ASN D CA  1 
ATOM 6876 C C   . ASN D 1 27  ? 105.346 168.364 111.854 1.00 111.55 ? 101 ASN D C   1 
ATOM 6877 O O   . ASN D 1 27  ? 104.598 169.261 112.255 1.00 112.19 ? 101 ASN D O   1 
ATOM 6878 C CB  . ASN D 1 27  ? 107.829 167.961 111.816 1.00 111.30 ? 101 ASN D CB  1 
ATOM 6879 C CG  . ASN D 1 27  ? 109.056 167.501 112.578 1.00 111.06 ? 101 ASN D CG  1 
ATOM 6880 O OD1 . ASN D 1 27  ? 109.139 166.352 113.010 1.00 111.21 ? 101 ASN D OD1 1 
ATOM 6881 N ND2 . ASN D 1 27  ? 110.020 168.400 112.744 1.00 110.57 ? 101 ASN D ND2 1 
ATOM 6882 N N   . LYS D 1 28  ? 105.146 167.721 110.708 1.00 106.21 ? 102 LYS D N   1 
ATOM 6883 C CA  . LYS D 1 28  ? 103.965 167.910 109.878 1.00 106.05 ? 102 LYS D CA  1 
ATOM 6884 C C   . LYS D 1 28  ? 103.126 166.641 109.944 1.00 105.99 ? 102 LYS D C   1 
ATOM 6885 O O   . LYS D 1 28  ? 103.676 165.535 109.978 1.00 105.28 ? 102 LYS D O   1 
ATOM 6886 C CB  . LYS D 1 28  ? 104.355 168.228 108.432 1.00 105.62 ? 102 LYS D CB  1 
ATOM 6887 C CG  . LYS D 1 28  ? 103.193 168.260 107.448 1.00 105.38 ? 102 LYS D CG  1 
ATOM 6888 C CD  . LYS D 1 28  ? 102.144 169.283 107.858 1.00 106.04 ? 102 LYS D CD  1 
ATOM 6889 C CE  . LYS D 1 28  ? 100.930 169.229 106.944 1.00 104.85 ? 102 LYS D CE  1 
ATOM 6890 N NZ  . LYS D 1 28  ? 101.291 169.479 105.522 1.00 104.84 ? 102 LYS D NZ  1 
ATOM 6891 N N   . SER D 1 29  ? 101.802 166.802 109.972 1.00 100.14 ? 103 SER D N   1 
ATOM 6892 C CA  . SER D 1 29  ? 100.881 165.678 110.089 1.00 97.93  ? 103 SER D CA  1 
ATOM 6893 C C   . SER D 1 29  ? 101.112 164.693 108.949 1.00 96.20  ? 103 SER D C   1 
ATOM 6894 O O   . SER D 1 29  ? 101.388 165.111 107.817 1.00 95.25  ? 103 SER D O   1 
ATOM 6895 C CB  . SER D 1 29  ? 99.432  166.168 110.088 1.00 95.61  ? 103 SER D CB  1 
ATOM 6896 O OG  . SER D 1 29  ? 99.118  166.825 108.873 1.00 95.82  ? 103 SER D OG  1 
ATOM 6897 N N   . PRO D 1 30  ? 101.025 163.389 109.208 1.00 90.54  ? 104 PRO D N   1 
ATOM 6898 C CA  . PRO D 1 30  ? 101.337 162.410 108.162 1.00 90.61  ? 104 PRO D CA  1 
ATOM 6899 C C   . PRO D 1 30  ? 100.377 162.509 106.987 1.00 95.70  ? 104 PRO D C   1 
ATOM 6900 O O   . PRO D 1 30  ? 99.180  162.755 107.148 1.00 96.14  ? 104 PRO D O   1 
ATOM 6901 C CB  . PRO D 1 30  ? 101.200 161.067 108.885 1.00 87.05  ? 104 PRO D CB  1 
ATOM 6902 C CG  . PRO D 1 30  ? 100.222 161.334 109.964 1.00 85.36  ? 104 PRO D CG  1 
ATOM 6903 C CD  . PRO D 1 30  ? 100.468 162.749 110.412 1.00 88.58  ? 104 PRO D CD  1 
ATOM 6904 N N   . LYS D 1 31  ? 100.926 162.320 105.788 1.00 98.52  ? 105 LYS D N   1 
ATOM 6905 C CA  . LYS D 1 31  ? 100.140 162.333 104.561 1.00 95.28  ? 105 LYS D CA  1 
ATOM 6906 C C   . LYS D 1 31  ? 100.451 161.186 103.614 1.00 94.29  ? 105 LYS D C   1 
ATOM 6907 O O   . LYS D 1 31  ? 99.621  160.894 102.745 1.00 92.07  ? 105 LYS D O   1 
ATOM 6908 C CB  . LYS D 1 31  ? 100.346 163.661 103.831 1.00 94.17  ? 105 LYS D CB  1 
ATOM 6909 C CG  . LYS D 1 31  ? 99.910  164.882 104.627 1.00 94.39  ? 105 LYS D CG  1 
ATOM 6910 C CD  . LYS D 1 31  ? 98.414  164.866 104.888 1.00 95.08  ? 105 LYS D CD  1 
ATOM 6911 C CE  . LYS D 1 31  ? 97.967  166.121 105.619 1.00 94.60  ? 105 LYS D CE  1 
ATOM 6912 N NZ  . LYS D 1 31  ? 96.506  166.108 105.904 1.00 95.06  ? 105 LYS D NZ  1 
ATOM 6913 N N   . SER D 1 32  ? 101.603 160.533 103.740 1.00 84.84  ? 106 SER D N   1 
ATOM 6914 C CA  . SER D 1 32  ? 101.997 159.441 102.861 1.00 80.99  ? 106 SER D CA  1 
ATOM 6915 C C   . SER D 1 32  ? 102.174 158.174 103.683 1.00 77.34  ? 106 SER D C   1 
ATOM 6916 O O   . SER D 1 32  ? 102.846 158.190 104.719 1.00 82.07  ? 106 SER D O   1 
ATOM 6917 C CB  . SER D 1 32  ? 103.291 159.774 102.113 1.00 85.25  ? 106 SER D CB  1 
ATOM 6918 O OG  . SER D 1 32  ? 103.770 158.648 101.397 1.00 86.30  ? 106 SER D OG  1 
ATOM 6919 N N   . VAL D 1 33  ? 101.568 157.083 103.222 1.00 62.39  ? 107 VAL D N   1 
ATOM 6920 C CA  . VAL D 1 33  ? 101.652 155.788 103.883 1.00 68.65  ? 107 VAL D CA  1 
ATOM 6921 C C   . VAL D 1 33  ? 102.098 154.756 102.860 1.00 69.94  ? 107 VAL D C   1 
ATOM 6922 O O   . VAL D 1 33  ? 101.485 154.630 101.794 1.00 74.44  ? 107 VAL D O   1 
ATOM 6923 C CB  . VAL D 1 33  ? 100.306 155.377 104.510 1.00 69.00  ? 107 VAL D CB  1 
ATOM 6924 C CG1 . VAL D 1 33  ? 100.384 153.964 105.056 1.00 70.99  ? 107 VAL D CG1 1 
ATOM 6925 C CG2 . VAL D 1 33  ? 99.916  156.349 105.608 1.00 70.81  ? 107 VAL D CG2 1 
ATOM 6926 N N   . LEU D 1 34  ? 103.158 154.021 103.180 1.00 56.24  ? 108 LEU D N   1 
ATOM 6927 C CA  . LEU D 1 34  ? 103.637 152.932 102.341 1.00 45.03  ? 108 LEU D CA  1 
ATOM 6928 C C   . LEU D 1 34  ? 103.281 151.611 103.008 1.00 50.60  ? 108 LEU D C   1 
ATOM 6929 O O   . LEU D 1 34  ? 103.746 151.327 104.116 1.00 59.28  ? 108 LEU D O   1 
ATOM 6930 C CB  . LEU D 1 34  ? 105.142 153.032 102.112 1.00 43.12  ? 108 LEU D CB  1 
ATOM 6931 C CG  . LEU D 1 34  ? 105.731 151.908 101.261 1.00 58.56  ? 108 LEU D CG  1 
ATOM 6932 C CD1 . LEU D 1 34  ? 105.085 151.888 99.884  1.00 59.76  ? 108 LEU D CD1 1 
ATOM 6933 C CD2 . LEU D 1 34  ? 107.236 152.058 101.144 1.00 60.63  ? 108 LEU D CD2 1 
ATOM 6934 N N   . VAL D 1 35  ? 102.466 150.806 102.333 1.00 51.09  ? 109 VAL D N   1 
ATOM 6935 C CA  . VAL D 1 35  ? 101.971 149.546 102.872 1.00 46.49  ? 109 VAL D CA  1 
ATOM 6936 C C   . VAL D 1 35  ? 102.612 148.403 102.102 1.00 52.42  ? 109 VAL D C   1 
ATOM 6937 O O   . VAL D 1 35  ? 102.526 148.350 100.869 1.00 66.55  ? 109 VAL D O   1 
ATOM 6938 C CB  . VAL D 1 35  ? 100.439 149.463 102.799 1.00 55.99  ? 109 VAL D CB  1 
ATOM 6939 C CG1 . VAL D 1 35  ? 99.955  148.166 103.416 1.00 60.09  ? 109 VAL D CG1 1 
ATOM 6940 C CG2 . VAL D 1 35  ? 99.814  150.657 103.493 1.00 58.14  ? 109 VAL D CG2 1 
ATOM 6941 N N   . ILE D 1 36  ? 103.253 147.493 102.827 1.00 51.11  ? 110 ILE D N   1 
ATOM 6942 C CA  . ILE D 1 36  ? 103.906 146.327 102.249 1.00 51.59  ? 110 ILE D CA  1 
ATOM 6943 C C   . ILE D 1 36  ? 103.221 145.085 102.796 1.00 55.71  ? 110 ILE D C   1 
ATOM 6944 O O   . ILE D 1 36  ? 103.090 144.928 104.015 1.00 62.29  ? 110 ILE D O   1 
ATOM 6945 C CB  . ILE D 1 36  ? 105.413 146.294 102.563 1.00 49.34  ? 110 ILE D CB  1 
ATOM 6946 C CG1 . ILE D 1 36  ? 106.133 147.502 101.962 1.00 49.48  ? 110 ILE D CG1 1 
ATOM 6947 C CG2 . ILE D 1 36  ? 106.033 145.004 102.054 1.00 57.01  ? 110 ILE D CG2 1 
ATOM 6948 C CD1 . ILE D 1 36  ? 106.225 148.688 102.881 1.00 51.09  ? 110 ILE D CD1 1 
ATOM 6949 N N   . LYS D 1 37  ? 102.788 144.207 101.900 1.00 75.84  ? 111 LYS D N   1 
ATOM 6950 C CA  . LYS D 1 37  ? 102.178 142.942 102.269 1.00 79.16  ? 111 LYS D CA  1 
ATOM 6951 C C   . LYS D 1 37  ? 103.209 141.828 102.142 1.00 86.99  ? 111 LYS D C   1 
ATOM 6952 O O   . LYS D 1 37  ? 104.126 141.901 101.320 1.00 89.69  ? 111 LYS D O   1 
ATOM 6953 C CB  . LYS D 1 37  ? 100.963 142.642 101.384 1.00 86.78  ? 111 LYS D CB  1 
ATOM 6954 C CG  . LYS D 1 37  ? 100.133 141.447 101.830 1.00 88.47  ? 111 LYS D CG  1 
ATOM 6955 C CD  . LYS D 1 37  ? 98.921  141.253 100.933 1.00 88.58  ? 111 LYS D CD  1 
ATOM 6956 C CE  . LYS D 1 37  ? 99.338  141.031 99.490  1.00 84.78  ? 111 LYS D CE  1 
ATOM 6957 N NZ  . LYS D 1 37  ? 98.168  140.837 98.594  1.00 86.66  ? 111 LYS D NZ  1 
ATOM 6958 N N   . LYS D 1 38  ? 103.055 140.794 102.973 1.00 100.33 ? 112 LYS D N   1 
ATOM 6959 C CA  . LYS D 1 38  ? 103.980 139.666 102.944 1.00 103.94 ? 112 LYS D CA  1 
ATOM 6960 C C   . LYS D 1 38  ? 103.938 138.921 101.615 1.00 102.82 ? 112 LYS D C   1 
ATOM 6961 O O   . LYS D 1 38  ? 104.898 138.217 101.282 1.00 101.97 ? 112 LYS D O   1 
ATOM 6962 C CB  . LYS D 1 38  ? 103.669 138.716 104.105 1.00 102.49 ? 112 LYS D CB  1 
ATOM 6963 C CG  . LYS D 1 38  ? 104.607 137.525 104.238 1.00 101.75 ? 112 LYS D CG  1 
ATOM 6964 C CD  . LYS D 1 38  ? 104.303 136.721 105.491 1.00 100.88 ? 112 LYS D CD  1 
ATOM 6965 C CE  . LYS D 1 38  ? 103.016 135.927 105.340 1.00 99.93  ? 112 LYS D CE  1 
ATOM 6966 N NZ  . LYS D 1 38  ? 102.766 135.044 106.513 1.00 98.79  ? 112 LYS D NZ  1 
ATOM 6967 N N   . MET D 1 39  ? 102.850 139.066 100.853 1.00 111.35 ? 113 MET D N   1 
ATOM 6968 C CA  . MET D 1 39  ? 102.675 138.450 99.539  1.00 112.57 ? 113 MET D CA  1 
ATOM 6969 C C   . MET D 1 39  ? 102.580 136.932 99.627  1.00 113.32 ? 113 MET D C   1 
ATOM 6970 O O   . MET D 1 39  ? 102.915 136.337 100.657 1.00 112.69 ? 113 MET D O   1 
ATOM 6971 C CB  . MET D 1 39  ? 103.813 138.849 98.591  1.00 111.05 ? 113 MET D CB  1 
ATOM 6972 C CG  . MET D 1 39  ? 104.004 140.346 98.436  1.00 110.72 ? 113 MET D CG  1 
ATOM 6973 S SD  . MET D 1 39  ? 102.509 141.168 97.865  1.00 118.93 ? 113 MET D SD  1 
ATOM 6974 C CE  . MET D 1 39  ? 102.252 140.338 96.300  1.00 111.25 ? 113 MET D CE  1 
ATOM 6975 N N   . ARG D 1 40  ? 102.115 136.303 98.544  1.00 113.48 ? 114 ARG D N   1 
ATOM 6976 C CA  . ARG D 1 40  ? 102.004 134.846 98.452  1.00 113.79 ? 114 ARG D CA  1 
ATOM 6977 C C   . ARG D 1 40  ? 101.176 134.270 99.599  1.00 112.66 ? 114 ARG D C   1 
ATOM 6978 O O   . ARG D 1 40  ? 101.498 133.218 100.154 1.00 112.91 ? 114 ARG D O   1 
ATOM 6979 C CB  . ARG D 1 40  ? 103.386 134.191 98.400  1.00 114.03 ? 114 ARG D CB  1 
ATOM 6980 C CG  . ARG D 1 40  ? 104.247 134.642 97.231  1.00 113.23 ? 114 ARG D CG  1 
ATOM 6981 C CD  . ARG D 1 40  ? 105.668 134.116 97.356  1.00 112.71 ? 114 ARG D CD  1 
ATOM 6982 N NE  . ARG D 1 40  ? 105.706 132.663 97.460  1.00 114.53 ? 114 ARG D NE  1 
ATOM 6983 C CZ  . ARG D 1 40  ? 106.814 131.951 97.618  1.00 115.74 ? 114 ARG D CZ  1 
ATOM 6984 N NH1 . ARG D 1 40  ? 108.001 132.529 97.694  1.00 115.57 ? 114 ARG D NH1 1 
ATOM 6985 N NH2 . ARG D 1 40  ? 106.728 130.626 97.701  1.00 114.03 ? 114 ARG D NH2 1 
ATOM 6986 N N   . ASP D 1 41  ? 100.098 134.964 99.958  1.00 102.50 ? 115 ASP D N   1 
ATOM 6987 C CA  . ASP D 1 41  ? 99.226  134.509 101.039 1.00 102.19 ? 115 ASP D CA  1 
ATOM 6988 C C   . ASP D 1 41  ? 97.827  135.046 100.778 1.00 105.12 ? 115 ASP D C   1 
ATOM 6989 O O   . ASP D 1 41  ? 97.604  136.259 100.845 1.00 105.95 ? 115 ASP D O   1 
ATOM 6990 C CB  . ASP D 1 41  ? 99.748  134.970 102.397 1.00 102.97 ? 115 ASP D CB  1 
ATOM 6991 C CG  . ASP D 1 41  ? 99.059  134.272 103.555 1.00 104.76 ? 115 ASP D CG  1 
ATOM 6992 O OD1 . ASP D 1 41  ? 98.186  133.414 103.304 1.00 103.46 ? 115 ASP D OD1 1 
ATOM 6993 O OD2 . ASP D 1 41  ? 99.391  134.582 104.718 1.00 103.93 ? 115 ASP D OD2 1 
ATOM 6994 N N   . ALA D 1 42  ? 96.889  134.144 100.481 1.00 104.02 ? 116 ALA D N   1 
ATOM 6995 C CA  . ALA D 1 42  ? 95.510  134.559 100.252 1.00 104.00 ? 116 ALA D CA  1 
ATOM 6996 C C   . ALA D 1 42  ? 94.850  135.053 101.532 1.00 102.38 ? 116 ALA D C   1 
ATOM 6997 O O   . ALA D 1 42  ? 93.944  135.890 101.477 1.00 100.93 ? 116 ALA D O   1 
ATOM 6998 C CB  . ALA D 1 42  ? 94.706  133.407 99.650  1.00 102.64 ? 116 ALA D CB  1 
ATOM 6999 N N   . SER D 1 43  ? 95.287  134.549 102.688 1.00 98.68  ? 117 SER D N   1 
ATOM 7000 C CA  . SER D 1 43  ? 94.710  134.977 103.956 1.00 99.85  ? 117 SER D CA  1 
ATOM 7001 C C   . SER D 1 43  ? 94.952  136.453 104.236 1.00 100.48 ? 117 SER D C   1 
ATOM 7002 O O   . SER D 1 43  ? 94.247  137.037 105.065 1.00 101.76 ? 117 SER D O   1 
ATOM 7003 C CB  . SER D 1 43  ? 95.273  134.135 105.101 1.00 100.56 ? 117 SER D CB  1 
ATOM 7004 O OG  . SER D 1 43  ? 94.736  134.544 106.347 1.00 98.95  ? 117 SER D OG  1 
ATOM 7005 N N   . LEU D 1 44  ? 95.925  137.065 103.568 1.00 98.51  ? 118 LEU D N   1 
ATOM 7006 C CA  . LEU D 1 44  ? 96.250  138.467 103.777 1.00 98.45  ? 118 LEU D CA  1 
ATOM 7007 C C   . LEU D 1 44  ? 95.527  139.397 102.813 1.00 100.22 ? 118 LEU D C   1 
ATOM 7008 O O   . LEU D 1 44  ? 95.785  140.604 102.834 1.00 103.31 ? 118 LEU D O   1 
ATOM 7009 C CB  . LEU D 1 44  ? 97.761  138.681 103.654 1.00 98.76  ? 118 LEU D CB  1 
ATOM 7010 C CG  . LEU D 1 44  ? 98.637  137.873 104.611 1.00 101.94 ? 118 LEU D CG  1 
ATOM 7011 C CD1 . LEU D 1 44  ? 100.091 138.292 104.483 1.00 99.96  ? 118 LEU D CD1 1 
ATOM 7012 C CD2 . LEU D 1 44  ? 98.157  138.027 106.043 1.00 99.06  ? 118 LEU D CD2 1 
ATOM 7013 N N   . LEU D 1 45  ? 94.633  138.874 101.972 1.00 103.03 ? 119 LEU D N   1 
ATOM 7014 C CA  . LEU D 1 45  ? 93.969  139.711 100.977 1.00 104.18 ? 119 LEU D CA  1 
ATOM 7015 C C   . LEU D 1 45  ? 92.892  140.588 101.608 1.00 104.40 ? 119 LEU D C   1 
ATOM 7016 O O   . LEU D 1 45  ? 92.939  141.818 101.501 1.00 103.19 ? 119 LEU D O   1 
ATOM 7017 C CB  . LEU D 1 45  ? 93.373  138.838 99.869  1.00 104.50 ? 119 LEU D CB  1 
ATOM 7018 C CG  . LEU D 1 45  ? 94.359  137.974 99.079  1.00 105.73 ? 119 LEU D CG  1 
ATOM 7019 C CD1 . LEU D 1 45  ? 93.631  137.148 98.030  1.00 103.21 ? 119 LEU D CD1 1 
ATOM 7020 C CD2 . LEU D 1 45  ? 95.433  138.837 98.436  1.00 105.30 ? 119 LEU D CD2 1 
ATOM 7021 N N   . GLN D 1 46  ? 91.906  139.969 102.257 1.00 106.05 ? 120 GLN D N   1 
ATOM 7022 C CA  . GLN D 1 46  ? 90.795  140.730 102.830 1.00 105.75 ? 120 GLN D CA  1 
ATOM 7023 C C   . GLN D 1 46  ? 91.235  141.731 103.894 1.00 104.54 ? 120 GLN D C   1 
ATOM 7024 O O   . GLN D 1 46  ? 90.743  142.874 103.871 1.00 102.03 ? 120 GLN D O   1 
ATOM 7025 C CB  . GLN D 1 46  ? 89.739  139.760 103.370 1.00 103.77 ? 120 GLN D CB  1 
ATOM 7026 C CG  . GLN D 1 46  ? 88.520  140.435 103.974 1.00 104.19 ? 120 GLN D CG  1 
ATOM 7027 C CD  . GLN D 1 46  ? 87.523  139.440 104.533 1.00 105.49 ? 120 GLN D CD  1 
ATOM 7028 O OE1 . GLN D 1 46  ? 87.775  138.235 104.550 1.00 104.08 ? 120 GLN D OE1 1 
ATOM 7029 N NE2 . GLN D 1 46  ? 86.383  139.940 104.996 1.00 106.03 ? 120 GLN D NE2 1 
ATOM 7030 N N   . PRO D 1 47  ? 92.095  141.384 104.862 1.00 104.45 ? 121 PRO D N   1 
ATOM 7031 C CA  . PRO D 1 47  ? 92.568  142.420 105.796 1.00 103.40 ? 121 PRO D CA  1 
ATOM 7032 C C   . PRO D 1 47  ? 93.309  143.551 105.107 1.00 100.65 ? 121 PRO D C   1 
ATOM 7033 O O   . PRO D 1 47  ? 93.178  144.713 105.513 1.00 101.61 ? 121 PRO D O   1 
ATOM 7034 C CB  . PRO D 1 47  ? 93.475  141.637 106.754 1.00 103.25 ? 121 PRO D CB  1 
ATOM 7035 C CG  . PRO D 1 47  ? 93.011  140.229 106.652 1.00 102.33 ? 121 PRO D CG  1 
ATOM 7036 C CD  . PRO D 1 47  ? 92.616  140.054 105.226 1.00 103.61 ? 121 PRO D CD  1 
ATOM 7037 N N   . PHE D 1 48  ? 94.084  143.240 104.066 1.00 92.38  ? 122 PHE D N   1 
ATOM 7038 C CA  . PHE D 1 48  ? 94.757  144.287 103.306 1.00 95.28  ? 122 PHE D CA  1 
ATOM 7039 C C   . PHE D 1 48  ? 93.745  145.209 102.643 1.00 96.71  ? 122 PHE D C   1 
ATOM 7040 O O   . PHE D 1 48  ? 93.915  146.433 102.641 1.00 97.05  ? 122 PHE D O   1 
ATOM 7041 C CB  . PHE D 1 48  ? 95.685  143.659 102.265 1.00 95.47  ? 122 PHE D CB  1 
ATOM 7042 C CG  . PHE D 1 48  ? 96.376  144.654 101.376 1.00 90.39  ? 122 PHE D CG  1 
ATOM 7043 C CD1 . PHE D 1 48  ? 97.469  145.366 101.831 1.00 90.57  ? 122 PHE D CD1 1 
ATOM 7044 C CD2 . PHE D 1 48  ? 95.947  144.857 100.078 1.00 93.46  ? 122 PHE D CD2 1 
ATOM 7045 C CE1 . PHE D 1 48  ? 98.111  146.272 101.015 1.00 88.99  ? 122 PHE D CE1 1 
ATOM 7046 C CE2 . PHE D 1 48  ? 96.586  145.763 99.257  1.00 95.96  ? 122 PHE D CE2 1 
ATOM 7047 C CZ  . PHE D 1 48  ? 97.671  146.469 99.727  1.00 92.54  ? 122 PHE D CZ  1 
ATOM 7048 N N   . LYS D 1 49  ? 92.676  144.635 102.086 1.00 102.23 ? 123 LYS D N   1 
ATOM 7049 C CA  . LYS D 1 49  ? 91.628  145.447 101.479 1.00 103.18 ? 123 LYS D CA  1 
ATOM 7050 C C   . LYS D 1 49  ? 90.962  146.347 102.510 1.00 102.10 ? 123 LYS D C   1 
ATOM 7051 O O   . LYS D 1 49  ? 90.720  147.531 102.248 1.00 100.69 ? 123 LYS D O   1 
ATOM 7052 C CB  . LYS D 1 49  ? 90.590  144.546 100.809 1.00 104.01 ? 123 LYS D CB  1 
ATOM 7053 C CG  . LYS D 1 49  ? 91.133  143.705 99.665  1.00 103.28 ? 123 LYS D CG  1 
ATOM 7054 C CD  . LYS D 1 49  ? 90.106  142.683 99.202  1.00 103.19 ? 123 LYS D CD  1 
ATOM 7055 C CE  . LYS D 1 49  ? 90.616  141.886 98.014  1.00 102.70 ? 123 LYS D CE  1 
ATOM 7056 N NZ  . LYS D 1 49  ? 90.768  142.737 96.802  1.00 102.87 ? 123 LYS D NZ  1 
ATOM 7057 N N   . GLU D 1 50  ? 90.657  145.800 103.688 1.00 100.66 ? 124 GLU D N   1 
ATOM 7058 C CA  . GLU D 1 50  ? 90.017  146.601 104.727 1.00 99.35  ? 124 GLU D CA  1 
ATOM 7059 C C   . GLU D 1 50  ? 90.917  147.746 105.171 1.00 98.87  ? 124 GLU D C   1 
ATOM 7060 O O   . GLU D 1 50  ? 90.463  148.890 105.306 1.00 97.10  ? 124 GLU D O   1 
ATOM 7061 C CB  . GLU D 1 50  ? 89.647  145.721 105.919 1.00 99.16  ? 124 GLU D CB  1 
ATOM 7062 C CG  . GLU D 1 50  ? 88.564  144.700 105.626 1.00 100.88 ? 124 GLU D CG  1 
ATOM 7063 C CD  . GLU D 1 50  ? 88.272  143.808 106.815 1.00 102.93 ? 124 GLU D CD  1 
ATOM 7064 O OE1 . GLU D 1 50  ? 88.838  144.058 107.899 1.00 101.96 ? 124 GLU D OE1 1 
ATOM 7065 O OE2 . GLU D 1 50  ? 87.478  142.856 106.665 1.00 102.64 ? 124 GLU D OE2 1 
ATOM 7066 N N   . LEU D 1 51  ? 92.202  147.459 105.393 1.00 99.96  ? 125 LEU D N   1 
ATOM 7067 C CA  . LEU D 1 51  ? 93.132  148.501 105.813 1.00 101.71 ? 125 LEU D CA  1 
ATOM 7068 C C   . LEU D 1 51  ? 93.285  149.568 104.739 1.00 99.68  ? 125 LEU D C   1 
ATOM 7069 O O   . LEU D 1 51  ? 93.334  150.764 105.048 1.00 100.52 ? 125 LEU D O   1 
ATOM 7070 C CB  . LEU D 1 51  ? 94.489  147.888 106.158 1.00 103.43 ? 125 LEU D CB  1 
ATOM 7071 C CG  . LEU D 1 51  ? 95.571  148.859 106.632 1.00 99.57  ? 125 LEU D CG  1 
ATOM 7072 C CD1 . LEU D 1 51  ? 95.122  149.603 107.879 1.00 97.68  ? 125 LEU D CD1 1 
ATOM 7073 C CD2 . LEU D 1 51  ? 96.869  148.117 106.890 1.00 95.91  ? 125 LEU D CD2 1 
ATOM 7074 N N   . CYS D 1 52  ? 93.370  149.158 103.472 1.00 93.69  ? 126 CYS D N   1 
ATOM 7075 C CA  . CYS D 1 52  ? 93.512  150.131 102.396 1.00 93.10  ? 126 CYS D CA  1 
ATOM 7076 C C   . CYS D 1 52  ? 92.274  151.008 102.280 1.00 99.62  ? 126 CYS D C   1 
ATOM 7077 O O   . CYS D 1 52  ? 92.384  152.222 102.075 1.00 101.40 ? 126 CYS D O   1 
ATOM 7078 C CB  . CYS D 1 52  ? 93.798  149.417 101.078 1.00 92.52  ? 126 CYS D CB  1 
ATOM 7079 S SG  . CYS D 1 52  ? 95.418  148.641 101.017 1.00 85.22  ? 126 CYS D SG  1 
ATOM 7080 N N   . THR D 1 53  ? 91.084  150.415 102.415 1.00 102.07 ? 127 THR D N   1 
ATOM 7081 C CA  . THR D 1 53  ? 89.862  151.213 102.380 1.00 97.79  ? 127 THR D CA  1 
ATOM 7082 C C   . THR D 1 53  ? 89.822  152.204 103.534 1.00 96.60  ? 127 THR D C   1 
ATOM 7083 O O   . THR D 1 53  ? 89.453  153.370 103.347 1.00 95.87  ? 127 THR D O   1 
ATOM 7084 C CB  . THR D 1 53  ? 88.631  150.308 102.414 1.00 96.44  ? 127 THR D CB  1 
ATOM 7085 O OG1 . THR D 1 53  ? 88.764  149.356 103.476 1.00 98.51  ? 127 THR D OG1 1 
ATOM 7086 C CG2 . THR D 1 53  ? 88.472  149.573 101.091 1.00 95.32  ? 127 THR D CG2 1 
ATOM 7087 N N   . HIS D 1 54  ? 90.204  151.763 104.736 1.00 103.83 ? 128 HIS D N   1 
ATOM 7088 C CA  . HIS D 1 54  ? 90.207  152.675 105.876 1.00 106.91 ? 128 HIS D CA  1 
ATOM 7089 C C   . HIS D 1 54  ? 91.199  153.812 105.673 1.00 108.01 ? 128 HIS D C   1 
ATOM 7090 O O   . HIS D 1 54  ? 90.891  154.973 105.967 1.00 108.51 ? 128 HIS D O   1 
ATOM 7091 C CB  . HIS D 1 54  ? 90.524  151.920 107.166 1.00 108.61 ? 128 HIS D CB  1 
ATOM 7092 C CG  . HIS D 1 54  ? 90.612  152.806 108.370 1.00 108.78 ? 128 HIS D CG  1 
ATOM 7093 N ND1 . HIS D 1 54  ? 91.813  153.225 108.899 1.00 106.62 ? 128 HIS D ND1 1 
ATOM 7094 C CD2 . HIS D 1 54  ? 89.647  153.364 109.139 1.00 107.61 ? 128 HIS D CD2 1 
ATOM 7095 C CE1 . HIS D 1 54  ? 91.585  153.998 109.946 1.00 105.48 ? 128 HIS D CE1 1 
ATOM 7096 N NE2 . HIS D 1 54  ? 90.279  154.098 110.113 1.00 105.35 ? 128 HIS D NE2 1 
ATOM 7097 N N   . LEU D 1 55  ? 92.398  153.498 105.179 1.00 103.11 ? 129 LEU D N   1 
ATOM 7098 C CA  . LEU D 1 55  ? 93.399  154.536 104.957 1.00 100.65 ? 129 LEU D CA  1 
ATOM 7099 C C   . LEU D 1 55  ? 92.949  155.514 103.882 1.00 97.77  ? 129 LEU D C   1 
ATOM 7100 O O   . LEU D 1 55  ? 93.186  156.722 103.995 1.00 99.44  ? 129 LEU D O   1 
ATOM 7101 C CB  . LEU D 1 55  ? 94.740  153.906 104.584 1.00 100.26 ? 129 LEU D CB  1 
ATOM 7102 C CG  . LEU D 1 55  ? 95.453  153.131 105.693 1.00 103.29 ? 129 LEU D CG  1 
ATOM 7103 C CD1 . LEU D 1 55  ? 96.765  152.548 105.190 1.00 100.59 ? 129 LEU D CD1 1 
ATOM 7104 C CD2 . LEU D 1 55  ? 95.685  154.019 106.906 1.00 101.69 ? 129 LEU D CD2 1 
ATOM 7105 N N   . MET D 1 56  ? 92.298  155.014 102.831 1.00 99.76  ? 130 MET D N   1 
ATOM 7106 C CA  . MET D 1 56  ? 91.816  155.891 101.774 1.00 103.29 ? 130 MET D CA  1 
ATOM 7107 C C   . MET D 1 56  ? 90.603  156.697 102.213 1.00 103.51 ? 130 MET D C   1 
ATOM 7108 O O   . MET D 1 56  ? 90.312  157.737 101.611 1.00 104.55 ? 130 MET D O   1 
ATOM 7109 C CB  . MET D 1 56  ? 91.487  155.072 100.525 1.00 103.94 ? 130 MET D CB  1 
ATOM 7110 C CG  . MET D 1 56  ? 91.347  155.897 99.260  1.00 103.67 ? 130 MET D CG  1 
ATOM 7111 S SD  . MET D 1 56  ? 92.918  156.646 98.791  1.00 108.90 ? 130 MET D SD  1 
ATOM 7112 C CE  . MET D 1 56  ? 93.916  155.185 98.514  1.00 100.79 ? 130 MET D CE  1 
ATOM 7113 N N   . GLU D 1 57  ? 89.891  156.242 103.247 1.00 102.74 ? 131 GLU D N   1 
ATOM 7114 C CA  . GLU D 1 57  ? 88.785  157.028 103.783 1.00 102.74 ? 131 GLU D CA  1 
ATOM 7115 C C   . GLU D 1 57  ? 89.275  158.370 104.308 1.00 103.48 ? 131 GLU D C   1 
ATOM 7116 O O   . GLU D 1 57  ? 88.642  159.406 104.076 1.00 105.09 ? 131 GLU D O   1 
ATOM 7117 C CB  . GLU D 1 57  ? 88.070  156.246 104.884 1.00 103.99 ? 131 GLU D CB  1 
ATOM 7118 C CG  . GLU D 1 57  ? 86.853  156.950 105.455 1.00 105.78 ? 131 GLU D CG  1 
ATOM 7119 C CD  . GLU D 1 57  ? 86.216  156.179 106.594 1.00 106.03 ? 131 GLU D CD  1 
ATOM 7120 O OE1 . GLU D 1 57  ? 86.651  155.038 106.856 1.00 104.25 ? 131 GLU D OE1 1 
ATOM 7121 O OE2 . GLU D 1 57  ? 85.281  156.713 107.227 1.00 105.48 ? 131 GLU D OE2 1 
ATOM 7122 N N   . GLU D 1 58  ? 90.400  158.372 105.016 1.00 105.86 ? 132 GLU D N   1 
ATOM 7123 C CA  . GLU D 1 58  ? 91.014  159.617 105.441 1.00 106.43 ? 132 GLU D CA  1 
ATOM 7124 C C   . GLU D 1 58  ? 91.770  160.253 104.278 1.00 109.68 ? 132 GLU D C   1 
ATOM 7125 O O   . GLU D 1 58  ? 92.142  159.590 103.306 1.00 111.97 ? 132 GLU D O   1 
ATOM 7126 C CB  . GLU D 1 58  ? 91.957  159.377 106.619 1.00 106.94 ? 132 GLU D CB  1 
ATOM 7127 C CG  . GLU D 1 58  ? 91.296  158.703 107.811 1.00 108.95 ? 132 GLU D CG  1 
ATOM 7128 C CD  . GLU D 1 58  ? 92.273  158.398 108.929 1.00 110.51 ? 132 GLU D CD  1 
ATOM 7129 O OE1 . GLU D 1 58  ? 93.467  158.735 108.786 1.00 111.68 ? 132 GLU D OE1 1 
ATOM 7130 O OE2 . GLU D 1 58  ? 91.846  157.821 109.951 1.00 109.03 ? 132 GLU D OE2 1 
ATOM 7131 N N   . ASN D 1 59  ? 91.995  161.562 104.387 1.00 115.68 ? 133 ASN D N   1 
ATOM 7132 C CA  . ASN D 1 59  ? 92.669  162.323 103.336 1.00 114.99 ? 133 ASN D CA  1 
ATOM 7133 C C   . ASN D 1 59  ? 94.185  162.127 103.421 1.00 115.35 ? 133 ASN D C   1 
ATOM 7134 O O   . ASN D 1 59  ? 94.959  163.054 103.662 1.00 116.38 ? 133 ASN D O   1 
ATOM 7135 C CB  . ASN D 1 59  ? 92.289  163.795 103.426 1.00 115.52 ? 133 ASN D CB  1 
ATOM 7136 C CG  . ASN D 1 59  ? 92.386  164.339 104.840 1.00 118.37 ? 133 ASN D CG  1 
ATOM 7137 O OD1 . ASN D 1 59  ? 92.996  163.723 105.715 1.00 118.70 ? 133 ASN D OD1 1 
ATOM 7138 N ND2 . ASN D 1 59  ? 91.784  165.500 105.069 1.00 117.42 ? 133 ASN D ND2 1 
ATOM 7139 N N   . MET D 1 60  ? 94.603  160.881 103.212 1.00 100.54 ? 134 MET D N   1 
ATOM 7140 C CA  . MET D 1 60  ? 96.005  160.499 103.298 1.00 100.09 ? 134 MET D CA  1 
ATOM 7141 C C   . MET D 1 60  ? 96.403  159.776 102.022 1.00 97.81  ? 134 MET D C   1 
ATOM 7142 O O   . MET D 1 60  ? 95.726  158.832 101.604 1.00 95.82  ? 134 MET D O   1 
ATOM 7143 C CB  . MET D 1 60  ? 96.255  159.608 104.520 1.00 97.48  ? 134 MET D CB  1 
ATOM 7144 C CG  . MET D 1 60  ? 97.709  159.522 104.946 1.00 93.13  ? 134 MET D CG  1 
ATOM 7145 S SD  . MET D 1 60  ? 97.882  159.088 106.686 1.00 100.30 ? 134 MET D SD  1 
ATOM 7146 C CE  . MET D 1 60  ? 96.977  160.424 107.459 1.00 97.43  ? 134 MET D CE  1 
ATOM 7147 N N   . ILE D 1 61  ? 97.500  160.220 101.407 1.00 90.05  ? 135 ILE D N   1 
ATOM 7148 C CA  . ILE D 1 61  ? 97.993  159.577 100.196 1.00 87.63  ? 135 ILE D CA  1 
ATOM 7149 C C   . ILE D 1 61  ? 98.566  158.213 100.551 1.00 85.79  ? 135 ILE D C   1 
ATOM 7150 O O   . ILE D 1 61  ? 99.365  158.082 101.487 1.00 90.53  ? 135 ILE D O   1 
ATOM 7151 C CB  . ILE D 1 61  ? 99.041  160.460 99.504  1.00 88.29  ? 135 ILE D CB  1 
ATOM 7152 C CG1 . ILE D 1 61  ? 98.480  161.865 99.267  1.00 88.99  ? 135 ILE D CG1 1 
ATOM 7153 C CG2 . ILE D 1 61  ? 99.488  159.831 98.195  1.00 85.61  ? 135 ILE D CG2 1 
ATOM 7154 C CD1 . ILE D 1 61  ? 97.238  161.889 98.402  1.00 85.12  ? 135 ILE D CD1 1 
ATOM 7155 N N   . VAL D 1 62  ? 98.158  157.189 99.808  1.00 64.33  ? 136 VAL D N   1 
ATOM 7156 C CA  . VAL D 1 62  ? 98.548  155.812 100.081 1.00 62.86  ? 136 VAL D CA  1 
ATOM 7157 C C   . VAL D 1 62  ? 99.507  155.353 98.994  1.00 66.97  ? 136 VAL D C   1 
ATOM 7158 O O   . VAL D 1 62  ? 99.168  155.373 97.804  1.00 74.09  ? 136 VAL D O   1 
ATOM 7159 C CB  . VAL D 1 62  ? 97.328  154.883 100.160 1.00 67.45  ? 136 VAL D CB  1 
ATOM 7160 C CG1 . VAL D 1 62  ? 97.774  153.444 100.335 1.00 71.07  ? 136 VAL D CG1 1 
ATOM 7161 C CG2 . VAL D 1 62  ? 96.420  155.304 101.302 1.00 70.19  ? 136 VAL D CG2 1 
ATOM 7162 N N   . TYR D 1 63  ? 100.701 154.938 99.404  1.00 66.29  ? 137 TYR D N   1 
ATOM 7163 C CA  . TYR D 1 63  ? 101.667 154.306 98.520  1.00 54.81  ? 137 TYR D CA  1 
ATOM 7164 C C   . TYR D 1 63  ? 101.639 152.805 98.763  1.00 56.69  ? 137 TYR D C   1 
ATOM 7165 O O   . TYR D 1 63  ? 101.687 152.357 99.912  1.00 76.05  ? 137 TYR D O   1 
ATOM 7166 C CB  . TYR D 1 63  ? 103.077 154.842 98.761  1.00 66.04  ? 137 TYR D CB  1 
ATOM 7167 C CG  . TYR D 1 63  ? 103.424 156.091 97.991  1.00 66.63  ? 137 TYR D CG  1 
ATOM 7168 C CD1 . TYR D 1 63  ? 102.783 157.293 98.252  1.00 69.92  ? 137 TYR D CD1 1 
ATOM 7169 C CD2 . TYR D 1 63  ? 104.405 156.071 97.010  1.00 64.07  ? 137 TYR D CD2 1 
ATOM 7170 C CE1 . TYR D 1 63  ? 103.104 158.439 97.551  1.00 72.06  ? 137 TYR D CE1 1 
ATOM 7171 C CE2 . TYR D 1 63  ? 104.733 157.209 96.305  1.00 66.53  ? 137 TYR D CE2 1 
ATOM 7172 C CZ  . TYR D 1 63  ? 104.080 158.391 96.579  1.00 72.37  ? 137 TYR D CZ  1 
ATOM 7173 O OH  . TYR D 1 63  ? 104.403 159.529 95.876  1.00 75.98  ? 137 TYR D OH  1 
ATOM 7174 N N   . VAL D 1 64  ? 101.545 152.038 97.689  1.00 44.91  ? 138 VAL D N   1 
ATOM 7175 C CA  . VAL D 1 64  ? 101.627 150.587 97.753  1.00 56.93  ? 138 VAL D CA  1 
ATOM 7176 C C   . VAL D 1 64  ? 102.623 150.152 96.691  1.00 64.66  ? 138 VAL D C   1 
ATOM 7177 O O   . VAL D 1 64  ? 102.788 150.819 95.665  1.00 68.89  ? 138 VAL D O   1 
ATOM 7178 C CB  . VAL D 1 64  ? 100.242 149.925 97.550  1.00 67.73  ? 138 VAL D CB  1 
ATOM 7179 C CG1 . VAL D 1 64  ? 100.346 148.406 97.523  1.00 69.94  ? 138 VAL D CG1 1 
ATOM 7180 C CG2 . VAL D 1 64  ? 99.278  150.368 98.639  1.00 62.74  ? 138 VAL D CG2 1 
ATOM 7181 N N   . GLU D 1 65  ? 103.310 149.041 96.951  1.00 74.19  ? 139 GLU D N   1 
ATOM 7182 C CA  . GLU D 1 65  ? 104.318 148.555 96.019  1.00 75.51  ? 139 GLU D CA  1 
ATOM 7183 C C   . GLU D 1 65  ? 103.709 148.356 94.637  1.00 76.94  ? 139 GLU D C   1 
ATOM 7184 O O   . GLU D 1 65  ? 102.592 147.851 94.497  1.00 79.56  ? 139 GLU D O   1 
ATOM 7185 C CB  . GLU D 1 65  ? 104.926 147.249 96.527  1.00 73.25  ? 139 GLU D CB  1 
ATOM 7186 C CG  . GLU D 1 65  ? 106.155 146.797 95.761  1.00 74.30  ? 139 GLU D CG  1 
ATOM 7187 C CD  . GLU D 1 65  ? 107.354 147.696 95.997  1.00 81.24  ? 139 GLU D CD  1 
ATOM 7188 O OE1 . GLU D 1 65  ? 107.374 148.410 97.022  1.00 80.53  ? 139 GLU D OE1 1 
ATOM 7189 O OE2 . GLU D 1 65  ? 108.277 147.689 95.156  1.00 82.42  ? 139 GLU D OE2 1 
ATOM 7190 N N   . LYS D 1 66  ? 104.455 148.776 93.613  1.00 69.83  ? 140 LYS D N   1 
ATOM 7191 C CA  . LYS D 1 66  ? 103.918 148.804 92.257  1.00 67.67  ? 140 LYS D CA  1 
ATOM 7192 C C   . LYS D 1 66  ? 103.528 147.412 91.776  1.00 62.44  ? 140 LYS D C   1 
ATOM 7193 O O   . LYS D 1 66  ? 102.481 147.238 91.144  1.00 64.08  ? 140 LYS D O   1 
ATOM 7194 C CB  . LYS D 1 66  ? 104.938 149.444 91.315  1.00 67.96  ? 140 LYS D CB  1 
ATOM 7195 C CG  . LYS D 1 66  ? 106.377 149.029 91.589  1.00 68.43  ? 140 LYS D CG  1 
ATOM 7196 C CD  . LYS D 1 66  ? 107.351 149.761 90.680  1.00 61.04  ? 140 LYS D CD  1 
ATOM 7197 C CE  . LYS D 1 66  ? 107.152 149.372 89.224  1.00 60.56  ? 140 LYS D CE  1 
ATOM 7198 N NZ  . LYS D 1 66  ? 107.371 147.916 89.001  1.00 63.76  ? 140 LYS D NZ  1 
ATOM 7199 N N   . LYS D 1 67  ? 104.350 146.405 92.072  1.00 72.76  ? 141 LYS D N   1 
ATOM 7200 C CA  . LYS D 1 67  ? 104.050 145.053 91.621  1.00 75.88  ? 141 LYS D CA  1 
ATOM 7201 C C   . LYS D 1 67  ? 103.018 144.350 92.492  1.00 73.98  ? 141 LYS D C   1 
ATOM 7202 O O   . LYS D 1 67  ? 102.585 143.249 92.139  1.00 73.61  ? 141 LYS D O   1 
ATOM 7203 C CB  . LYS D 1 67  ? 105.335 144.225 91.559  1.00 79.39  ? 141 LYS D CB  1 
ATOM 7204 C CG  . LYS D 1 67  ? 105.968 143.939 92.908  1.00 79.71  ? 141 LYS D CG  1 
ATOM 7205 C CD  . LYS D 1 67  ? 107.251 143.139 92.746  1.00 78.96  ? 141 LYS D CD  1 
ATOM 7206 C CE  . LYS D 1 67  ? 107.917 142.877 94.087  1.00 77.56  ? 141 LYS D CE  1 
ATOM 7207 N NZ  . LYS D 1 67  ? 107.102 141.976 94.948  1.00 76.65  ? 141 LYS D NZ  1 
ATOM 7208 N N   . VAL D 1 68  ? 102.623 144.942 93.620  1.00 78.65  ? 142 VAL D N   1 
ATOM 7209 C CA  . VAL D 1 68  ? 101.571 144.342 94.434  1.00 78.04  ? 142 VAL D CA  1 
ATOM 7210 C C   . VAL D 1 68  ? 100.224 144.463 93.736  1.00 79.61  ? 142 VAL D C   1 
ATOM 7211 O O   . VAL D 1 68  ? 99.446  143.503 93.687  1.00 82.44  ? 142 VAL D O   1 
ATOM 7212 C CB  . VAL D 1 68  ? 101.545 144.976 95.836  1.00 82.94  ? 142 VAL D CB  1 
ATOM 7213 C CG1 . VAL D 1 68  ? 100.248 144.631 96.552  1.00 83.67  ? 142 VAL D CG1 1 
ATOM 7214 C CG2 . VAL D 1 68  ? 102.736 144.503 96.646  1.00 83.26  ? 142 VAL D CG2 1 
ATOM 7215 N N   . LEU D 1 69  ? 99.930  145.633 93.174  1.00 86.81  ? 143 LEU D N   1 
ATOM 7216 C CA  . LEU D 1 69  ? 98.652  145.876 92.505  1.00 88.53  ? 143 LEU D CA  1 
ATOM 7217 C C   . LEU D 1 69  ? 98.626  145.353 91.073  1.00 90.75  ? 143 LEU D C   1 
ATOM 7218 O O   . LEU D 1 69  ? 98.158  146.021 90.148  1.00 90.39  ? 143 LEU D O   1 
ATOM 7219 C CB  . LEU D 1 69  ? 98.341  147.371 92.573  1.00 89.12  ? 143 LEU D CB  1 
ATOM 7220 C CG  . LEU D 1 69  ? 99.329  148.428 92.036  1.00 89.00  ? 143 LEU D CG  1 
ATOM 7221 C CD1 . LEU D 1 69  ? 99.206  148.753 90.548  1.00 89.67  ? 143 LEU D CD1 1 
ATOM 7222 C CD2 . LEU D 1 69  ? 99.236  149.706 92.864  1.00 85.61  ? 143 LEU D CD2 1 
ATOM 7223 N N   . GLU D 1 70  ? 99.068  144.109 90.877  1.00 91.75  ? 144 GLU D N   1 
ATOM 7224 C CA  . GLU D 1 70  ? 98.949  143.447 89.585  1.00 86.65  ? 144 GLU D CA  1 
ATOM 7225 C C   . GLU D 1 70  ? 98.769  141.942 89.734  1.00 86.36  ? 144 GLU D C   1 
ATOM 7226 O O   . GLU D 1 70  ? 98.858  141.221 88.733  1.00 88.33  ? 144 GLU D O   1 
ATOM 7227 C CB  . GLU D 1 70  ? 100.166 143.742 88.699  1.00 88.65  ? 144 GLU D CB  1 
ATOM 7228 C CG  . GLU D 1 70  ? 101.464 143.121 89.180  1.00 93.09  ? 144 GLU D CG  1 
ATOM 7229 C CD  . GLU D 1 70  ? 102.638 143.465 88.284  1.00 94.74  ? 144 GLU D CD  1 
ATOM 7230 O OE1 . GLU D 1 70  ? 102.431 144.183 87.283  1.00 91.68  ? 144 GLU D OE1 1 
ATOM 7231 O OE2 . GLU D 1 70  ? 103.767 143.019 88.580  1.00 96.80  ? 144 GLU D OE2 1 
ATOM 7232 N N   . ASP D 1 71  ? 98.533  141.450 90.944  1.00 97.09  ? 145 ASP D N   1 
ATOM 7233 C CA  . ASP D 1 71  ? 98.342  140.023 91.144  1.00 98.29  ? 145 ASP D CA  1 
ATOM 7234 C C   . ASP D 1 71  ? 97.024  139.581 90.514  1.00 99.36  ? 145 ASP D C   1 
ATOM 7235 O O   . ASP D 1 71  ? 96.087  140.381 90.410  1.00 100.62 ? 145 ASP D O   1 
ATOM 7236 C CB  . ASP D 1 71  ? 98.344  139.685 92.635  1.00 98.06  ? 145 ASP D CB  1 
ATOM 7237 C CG  . ASP D 1 71  ? 99.615  140.123 93.330  1.00 99.12  ? 145 ASP D CG  1 
ATOM 7238 O OD1 . ASP D 1 71  ? 100.674 140.163 92.670  1.00 100.20 ? 145 ASP D OD1 1 
ATOM 7239 O OD2 . ASP D 1 71  ? 99.553  140.429 94.539  1.00 99.64  ? 145 ASP D OD2 1 
ATOM 7240 N N   . PRO D 1 72  ? 96.919  138.325 90.071  1.00 109.54 ? 146 PRO D N   1 
ATOM 7241 C CA  . PRO D 1 72  ? 95.623  137.847 89.564  1.00 109.33 ? 146 PRO D CA  1 
ATOM 7242 C C   . PRO D 1 72  ? 94.517  137.929 90.599  1.00 106.88 ? 146 PRO D C   1 
ATOM 7243 O O   . PRO D 1 72  ? 93.365  138.208 90.249  1.00 107.95 ? 146 PRO D O   1 
ATOM 7244 C CB  . PRO D 1 72  ? 95.922  136.397 89.154  1.00 110.62 ? 146 PRO D CB  1 
ATOM 7245 C CG  . PRO D 1 72  ? 97.150  136.023 89.926  1.00 110.47 ? 146 PRO D CG  1 
ATOM 7246 C CD  . PRO D 1 72  ? 97.955  137.281 90.019  1.00 109.33 ? 146 PRO D CD  1 
ATOM 7247 N N   . ALA D 1 73  ? 94.840  137.700 91.874  1.00 99.71  ? 147 ALA D N   1 
ATOM 7248 C CA  . ALA D 1 73  ? 93.834  137.809 92.925  1.00 102.04 ? 147 ALA D CA  1 
ATOM 7249 C C   . ALA D 1 73  ? 93.341  139.242 93.077  1.00 103.08 ? 147 ALA D C   1 
ATOM 7250 O O   . ALA D 1 73  ? 92.144  139.474 93.282  1.00 100.20 ? 147 ALA D O   1 
ATOM 7251 C CB  . ALA D 1 73  ? 94.397  137.291 94.247  1.00 102.99 ? 147 ALA D CB  1 
ATOM 7252 N N   . ILE D 1 74  ? 94.247  140.217 92.986  1.00 106.92 ? 148 ILE D N   1 
ATOM 7253 C CA  . ILE D 1 74  ? 93.846  141.609 93.160  1.00 105.16 ? 148 ILE D CA  1 
ATOM 7254 C C   . ILE D 1 74  ? 93.231  142.171 91.883  1.00 105.76 ? 148 ILE D C   1 
ATOM 7255 O O   . ILE D 1 74  ? 92.517  143.179 91.927  1.00 107.13 ? 148 ILE D O   1 
ATOM 7256 C CB  . ILE D 1 74  ? 95.043  142.455 93.630  1.00 104.70 ? 148 ILE D CB  1 
ATOM 7257 C CG1 . ILE D 1 74  ? 94.566  143.604 94.520  1.00 106.64 ? 148 ILE D CG1 1 
ATOM 7258 C CG2 . ILE D 1 74  ? 95.831  142.992 92.443  1.00 101.18 ? 148 ILE D CG2 1 
ATOM 7259 C CD1 . ILE D 1 74  ? 94.019  143.153 95.856  1.00 107.08 ? 148 ILE D CD1 1 
ATOM 7260 N N   . ALA D 1 75  ? 93.490  141.544 90.734  1.00 111.20 ? 149 ALA D N   1 
ATOM 7261 C CA  . ALA D 1 75  ? 92.917  142.025 89.482  1.00 111.74 ? 149 ALA D CA  1 
ATOM 7262 C C   . ALA D 1 75  ? 91.537  141.429 89.228  1.00 113.30 ? 149 ALA D C   1 
ATOM 7263 O O   . ALA D 1 75  ? 90.655  142.108 88.691  1.00 111.70 ? 149 ALA D O   1 
ATOM 7264 C CB  . ALA D 1 75  ? 93.856  141.709 88.318  1.00 112.85 ? 149 ALA D CB  1 
ATOM 7265 N N   . SER D 1 76  ? 91.336  140.162 89.601  1.00 120.78 ? 150 SER D N   1 
ATOM 7266 C CA  . SER D 1 76  ? 90.055  139.506 89.357  1.00 119.59 ? 150 SER D CA  1 
ATOM 7267 C C   . SER D 1 76  ? 88.932  140.162 90.149  1.00 118.98 ? 150 SER D C   1 
ATOM 7268 O O   . SER D 1 76  ? 87.818  140.327 89.637  1.00 117.94 ? 150 SER D O   1 
ATOM 7269 C CB  . SER D 1 76  ? 90.155  138.019 89.700  1.00 119.15 ? 150 SER D CB  1 
ATOM 7270 O OG  . SER D 1 76  ? 91.181  137.390 88.951  1.00 118.77 ? 150 SER D OG  1 
ATOM 7271 N N   . ASP D 1 77  ? 89.201  140.542 91.394  1.00 122.87 ? 151 ASP D N   1 
ATOM 7272 C CA  . ASP D 1 77  ? 88.190  141.155 92.251  1.00 124.67 ? 151 ASP D CA  1 
ATOM 7273 C C   . ASP D 1 77  ? 87.940  142.576 91.764  1.00 124.46 ? 151 ASP D C   1 
ATOM 7274 O O   . ASP D 1 77  ? 88.690  143.500 92.086  1.00 124.52 ? 151 ASP D O   1 
ATOM 7275 C CB  . ASP D 1 77  ? 88.646  141.133 93.706  1.00 122.78 ? 151 ASP D CB  1 
ATOM 7276 C CG  . ASP D 1 77  ? 87.539  141.510 94.677  1.00 122.28 ? 151 ASP D CG  1 
ATOM 7277 O OD1 . ASP D 1 77  ? 86.926  142.584 94.509  1.00 120.96 ? 151 ASP D OD1 1 
ATOM 7278 O OD2 . ASP D 1 77  ? 87.281  140.724 95.613  1.00 122.62 ? 151 ASP D OD2 1 
ATOM 7279 N N   . GLU D 1 78  ? 86.876  142.756 90.979  1.00 121.51 ? 152 GLU D N   1 
ATOM 7280 C CA  . GLU D 1 78  ? 86.544  144.069 90.443  1.00 121.36 ? 152 GLU D CA  1 
ATOM 7281 C C   . GLU D 1 78  ? 85.958  145.003 91.492  1.00 119.12 ? 152 GLU D C   1 
ATOM 7282 O O   . GLU D 1 78  ? 85.921  146.218 91.266  1.00 118.96 ? 152 GLU D O   1 
ATOM 7283 C CB  . GLU D 1 78  ? 85.565  143.934 89.273  1.00 121.63 ? 152 GLU D CB  1 
ATOM 7284 C CG  . GLU D 1 78  ? 84.165  143.488 89.669  1.00 120.63 ? 152 GLU D CG  1 
ATOM 7285 C CD  . GLU D 1 78  ? 84.074  141.996 89.928  1.00 121.27 ? 152 GLU D CD  1 
ATOM 7286 O OE1 . GLU D 1 78  ? 85.016  141.267 89.552  1.00 122.28 ? 152 GLU D OE1 1 
ATOM 7287 O OE2 . GLU D 1 78  ? 83.060  141.553 90.507  1.00 120.38 ? 152 GLU D OE2 1 
ATOM 7288 N N   . SER D 1 79  ? 85.496  144.469 92.625  1.00 105.78 ? 153 SER D N   1 
ATOM 7289 C CA  . SER D 1 79  ? 84.974  145.329 93.682  1.00 106.12 ? 153 SER D CA  1 
ATOM 7290 C C   . SER D 1 79  ? 86.059  146.245 94.230  1.00 107.79 ? 153 SER D C   1 
ATOM 7291 O O   . SER D 1 79  ? 85.816  147.432 94.476  1.00 106.53 ? 153 SER D O   1 
ATOM 7292 C CB  . SER D 1 79  ? 84.370  144.480 94.799  1.00 106.10 ? 153 SER D CB  1 
ATOM 7293 O OG  . SER D 1 79  ? 83.854  145.298 95.834  1.00 108.05 ? 153 SER D OG  1 
ATOM 7294 N N   . PHE D 1 80  ? 87.269  145.714 94.419  1.00 107.09 ? 154 PHE D N   1 
ATOM 7295 C CA  . PHE D 1 80  ? 88.382  146.517 94.911  1.00 106.62 ? 154 PHE D CA  1 
ATOM 7296 C C   . PHE D 1 80  ? 88.891  147.514 93.879  1.00 104.67 ? 154 PHE D C   1 
ATOM 7297 O O   . PHE D 1 80  ? 89.699  148.384 94.228  1.00 104.58 ? 154 PHE D O   1 
ATOM 7298 C CB  . PHE D 1 80  ? 89.522  145.604 95.365  1.00 103.58 ? 154 PHE D CB  1 
ATOM 7299 C CG  . PHE D 1 80  ? 90.482  146.263 96.311  1.00 105.44 ? 154 PHE D CG  1 
ATOM 7300 C CD1 . PHE D 1 80  ? 90.125  146.500 97.627  1.00 105.98 ? 154 PHE D CD1 1 
ATOM 7301 C CD2 . PHE D 1 80  ? 91.747  146.630 95.891  1.00 105.79 ? 154 PHE D CD2 1 
ATOM 7302 C CE1 . PHE D 1 80  ? 91.008  147.107 98.498  1.00 107.46 ? 154 PHE D CE1 1 
ATOM 7303 C CE2 . PHE D 1 80  ? 92.635  147.233 96.758  1.00 104.09 ? 154 PHE D CE2 1 
ATOM 7304 C CZ  . PHE D 1 80  ? 92.265  147.470 98.064  1.00 105.59 ? 154 PHE D CZ  1 
ATOM 7305 N N   . GLY D 1 81  ? 88.441  147.415 92.627  1.00 96.74  ? 155 GLY D N   1 
ATOM 7306 C CA  . GLY D 1 81  ? 88.843  148.374 91.616  1.00 97.81  ? 155 GLY D CA  1 
ATOM 7307 C C   . GLY D 1 81  ? 88.390  149.789 91.901  1.00 96.99  ? 155 GLY D C   1 
ATOM 7308 O O   . GLY D 1 81  ? 88.920  150.730 91.302  1.00 98.54  ? 155 GLY D O   1 
ATOM 7309 N N   . ALA D 1 82  ? 87.418  149.960 92.799  1.00 87.07  ? 156 ALA D N   1 
ATOM 7310 C CA  . ALA D 1 82  ? 86.987  151.302 93.173  1.00 89.87  ? 156 ALA D CA  1 
ATOM 7311 C C   . ALA D 1 82  ? 88.120  152.076 93.830  1.00 91.59  ? 156 ALA D C   1 
ATOM 7312 O O   . ALA D 1 82  ? 88.308  153.268 93.561  1.00 94.18  ? 156 ALA D O   1 
ATOM 7313 C CB  . ALA D 1 82  ? 85.777  151.226 94.104  1.00 91.38  ? 156 ALA D CB  1 
ATOM 7314 N N   . VAL D 1 83  ? 88.892  151.412 94.695  1.00 95.32  ? 157 VAL D N   1 
ATOM 7315 C CA  . VAL D 1 83  ? 90.016  152.060 95.364  1.00 97.56  ? 157 VAL D CA  1 
ATOM 7316 C C   . VAL D 1 83  ? 91.357  151.710 94.740  1.00 94.63  ? 157 VAL D C   1 
ATOM 7317 O O   . VAL D 1 83  ? 92.369  152.341 95.083  1.00 94.39  ? 157 VAL D O   1 
ATOM 7318 C CB  . VAL D 1 83  ? 90.042  151.705 96.863  1.00 99.16  ? 157 VAL D CB  1 
ATOM 7319 C CG1 . VAL D 1 83  ? 88.785  152.217 97.549  1.00 96.95  ? 157 VAL D CG1 1 
ATOM 7320 C CG2 . VAL D 1 83  ? 90.179  150.204 97.045  1.00 98.12  ? 157 VAL D CG2 1 
ATOM 7321 N N   . LYS D 1 84  ? 91.404  150.722 93.840  1.00 90.98  ? 158 LYS D N   1 
ATOM 7322 C CA  . LYS D 1 84  ? 92.664  150.367 93.194  1.00 92.76  ? 158 LYS D CA  1 
ATOM 7323 C C   . LYS D 1 84  ? 93.265  151.554 92.452  1.00 93.47  ? 158 LYS D C   1 
ATOM 7324 O O   . LYS D 1 84  ? 94.491  151.693 92.377  1.00 95.53  ? 158 LYS D O   1 
ATOM 7325 C CB  . LYS D 1 84  ? 92.452  149.197 92.235  1.00 95.36  ? 158 LYS D CB  1 
ATOM 7326 C CG  . LYS D 1 84  ? 92.741  147.835 92.836  1.00 96.29  ? 158 LYS D CG  1 
ATOM 7327 C CD  . LYS D 1 84  ? 92.574  146.726 91.809  1.00 96.00  ? 158 LYS D CD  1 
ATOM 7328 C CE  . LYS D 1 84  ? 93.565  146.875 90.666  1.00 95.69  ? 158 LYS D CE  1 
ATOM 7329 N NZ  . LYS D 1 84  ? 93.427  145.778 89.668  1.00 96.02  ? 158 LYS D NZ  1 
ATOM 7330 N N   . LYS D 1 85  ? 92.417  152.420 91.896  1.00 100.92 ? 159 LYS D N   1 
ATOM 7331 C CA  . LYS D 1 85  ? 92.905  153.540 91.102  1.00 103.59 ? 159 LYS D CA  1 
ATOM 7332 C C   . LYS D 1 85  ? 93.598  154.596 91.952  1.00 101.87 ? 159 LYS D C   1 
ATOM 7333 O O   . LYS D 1 85  ? 94.409  155.366 91.425  1.00 102.47 ? 159 LYS D O   1 
ATOM 7334 C CB  . LYS D 1 85  ? 91.741  154.158 90.318  1.00 103.33 ? 159 LYS D CB  1 
ATOM 7335 C CG  . LYS D 1 85  ? 92.126  155.244 89.318  1.00 102.70 ? 159 LYS D CG  1 
ATOM 7336 C CD  . LYS D 1 85  ? 91.887  156.640 89.880  1.00 102.49 ? 159 LYS D CD  1 
ATOM 7337 C CE  . LYS D 1 85  ? 92.394  157.715 88.932  1.00 102.34 ? 159 LYS D CE  1 
ATOM 7338 N NZ  . LYS D 1 85  ? 92.247  159.080 89.509  1.00 101.74 ? 159 LYS D NZ  1 
ATOM 7339 N N   . LYS D 1 86  ? 93.323  154.638 93.252  1.00 88.55  ? 160 LYS D N   1 
ATOM 7340 C CA  . LYS D 1 86  ? 93.803  155.715 94.104  1.00 91.04  ? 160 LYS D CA  1 
ATOM 7341 C C   . LYS D 1 86  ? 95.157  155.427 94.742  1.00 95.40  ? 160 LYS D C   1 
ATOM 7342 O O   . LYS D 1 86  ? 95.578  156.179 95.627  1.00 96.78  ? 160 LYS D O   1 
ATOM 7343 C CB  . LYS D 1 86  ? 92.770  156.019 95.192  1.00 91.13  ? 160 LYS D CB  1 
ATOM 7344 C CG  . LYS D 1 86  ? 91.377  156.295 94.656  1.00 90.69  ? 160 LYS D CG  1 
ATOM 7345 C CD  . LYS D 1 86  ? 90.537  157.048 95.670  1.00 91.17  ? 160 LYS D CD  1 
ATOM 7346 C CE  . LYS D 1 86  ? 91.104  158.434 95.928  1.00 92.17  ? 160 LYS D CE  1 
ATOM 7347 N NZ  . LYS D 1 86  ? 90.264  159.208 96.883  1.00 91.18  ? 160 LYS D NZ  1 
ATOM 7348 N N   . PHE D 1 87  ? 95.846  154.370 94.322  1.00 74.95  ? 161 PHE D N   1 
ATOM 7349 C CA  . PHE D 1 87  ? 97.173  154.078 94.844  1.00 59.32  ? 161 PHE D CA  1 
ATOM 7350 C C   . PHE D 1 87  ? 98.208  154.988 94.187  1.00 62.10  ? 161 PHE D C   1 
ATOM 7351 O O   . PHE D 1 87  ? 97.881  155.926 93.454  1.00 70.98  ? 161 PHE D O   1 
ATOM 7352 C CB  . PHE D 1 87  ? 97.522  152.611 94.616  1.00 59.17  ? 161 PHE D CB  1 
ATOM 7353 C CG  . PHE D 1 87  ? 96.696  151.660 95.425  1.00 67.78  ? 161 PHE D CG  1 
ATOM 7354 C CD1 . PHE D 1 87  ? 96.150  152.053 96.634  1.00 74.57  ? 161 PHE D CD1 1 
ATOM 7355 C CD2 . PHE D 1 87  ? 96.468  150.370 94.981  1.00 69.49  ? 161 PHE D CD2 1 
ATOM 7356 C CE1 . PHE D 1 87  ? 95.389  151.178 97.383  1.00 73.94  ? 161 PHE D CE1 1 
ATOM 7357 C CE2 . PHE D 1 87  ? 95.710  149.490 95.725  1.00 69.93  ? 161 PHE D CE2 1 
ATOM 7358 C CZ  . PHE D 1 87  ? 95.169  149.894 96.927  1.00 71.55  ? 161 PHE D CZ  1 
ATOM 7359 N N   . THR D 1 88  ? 99.478  154.707 94.455  1.00 55.32  ? 162 THR D N   1 
ATOM 7360 C CA  . THR D 1 88  ? 100.567 155.465 93.850  1.00 60.01  ? 162 THR D CA  1 
ATOM 7361 C C   . THR D 1 88  ? 101.841 154.631 93.765  1.00 60.19  ? 162 THR D C   1 
ATOM 7362 O O   . THR D 1 88  ? 102.069 153.924 92.783  1.00 57.60  ? 162 THR D O   1 
ATOM 7363 C CB  . THR D 1 88  ? 100.833 156.756 94.646  1.00 61.22  ? 162 THR D CB  1 
ATOM 7364 O OG1 . THR D 1 88  ? 99.660  157.578 94.634  1.00 62.70  ? 162 THR D OG1 1 
ATOM 7365 C CG2 . THR D 1 88  ? 101.870 157.616 93.938  1.00 57.12  ? 162 THR D CG2 1 
ATOM 7366 N N   . ASN D 1 99  ? 112.102 158.712 100.060 1.00 94.41  ? 173 ASN D N   1 
ATOM 7367 C CA  . ASN D 1 99  ? 112.251 160.107 100.458 1.00 97.53  ? 173 ASN D CA  1 
ATOM 7368 C C   . ASN D 1 99  ? 110.904 160.819 100.484 1.00 95.56  ? 173 ASN D C   1 
ATOM 7369 O O   . ASN D 1 99  ? 110.813 161.981 100.877 1.00 94.55  ? 173 ASN D O   1 
ATOM 7370 C CB  . ASN D 1 99  ? 113.222 160.835 99.528  1.00 30.00  ? 173 ASN D CB  1 
ATOM 7371 C CG  . ASN D 1 99  ? 113.634 162.193 100.062 1.00 30.00  ? 173 ASN D CG  1 
ATOM 7372 O OD1 . ASN D 1 99  ? 113.706 162.401 101.273 1.00 30.00  ? 173 ASN D OD1 1 
ATOM 7373 N ND2 . ASN D 1 99  ? 113.908 163.127 99.158  1.00 30.00  ? 173 ASN D ND2 1 
ATOM 7374 N N   . GLN D 1 100 ? 109.856 160.112 100.063 1.00 85.72  ? 174 GLN D N   1 
ATOM 7375 C CA  . GLN D 1 100 ? 108.505 160.654 100.029 1.00 91.40  ? 174 GLN D CA  1 
ATOM 7376 C C   . GLN D 1 100 ? 107.541 159.885 100.924 1.00 95.22  ? 174 GLN D C   1 
ATOM 7377 O O   . GLN D 1 100 ? 106.330 160.123 100.864 1.00 96.21  ? 174 GLN D O   1 
ATOM 7378 C CB  . GLN D 1 100 ? 107.982 160.676 98.591  1.00 91.44  ? 174 GLN D CB  1 
ATOM 7379 C CG  . GLN D 1 100 ? 107.741 159.298 97.994  1.00 92.59  ? 174 GLN D CG  1 
ATOM 7380 C CD  . GLN D 1 100 ? 108.896 158.826 97.133  1.00 94.15  ? 174 GLN D CD  1 
ATOM 7381 O OE1 . GLN D 1 100 ? 109.970 159.426 97.130  1.00 94.61  ? 174 GLN D OE1 1 
ATOM 7382 N NE2 . GLN D 1 100 ? 108.679 157.743 96.395  1.00 91.67  ? 174 GLN D NE2 1 
ATOM 7383 N N   . ILE D 1 101 ? 108.046 158.972 101.750 1.00 84.59  ? 175 ILE D N   1 
ATOM 7384 C CA  . ILE D 1 101 ? 107.222 158.175 102.651 1.00 81.73  ? 175 ILE D CA  1 
ATOM 7385 C C   . ILE D 1 101 ? 107.376 158.717 104.064 1.00 77.01  ? 175 ILE D C   1 
ATOM 7386 O O   . ILE D 1 101 ? 108.498 158.953 104.529 1.00 80.09  ? 175 ILE D O   1 
ATOM 7387 C CB  . ILE D 1 101 ? 107.606 156.687 102.588 1.00 80.49  ? 175 ILE D CB  1 
ATOM 7388 C CG1 . ILE D 1 101 ? 107.497 156.167 101.154 1.00 79.13  ? 175 ILE D CG1 1 
ATOM 7389 C CG2 . ILE D 1 101 ? 106.742 155.872 103.538 1.00 80.81  ? 175 ILE D CG2 1 
ATOM 7390 C CD1 . ILE D 1 101 ? 106.110 156.283 100.568 1.00 76.87  ? 175 ILE D CD1 1 
ATOM 7391 N N   . ASP D 1 102 ? 106.250 158.917 104.746 1.00 66.29  ? 176 ASP D N   1 
ATOM 7392 C CA  . ASP D 1 102 ? 106.255 159.427 106.110 1.00 71.14  ? 176 ASP D CA  1 
ATOM 7393 C C   . ASP D 1 102 ? 105.994 158.355 107.156 1.00 73.13  ? 176 ASP D C   1 
ATOM 7394 O O   . ASP D 1 102 ? 106.421 158.514 108.304 1.00 78.89  ? 176 ASP D O   1 
ATOM 7395 C CB  . ASP D 1 102 ? 105.209 160.535 106.265 1.00 76.91  ? 176 ASP D CB  1 
ATOM 7396 C CG  . ASP D 1 102 ? 105.541 161.768 105.452 1.00 79.95  ? 176 ASP D CG  1 
ATOM 7397 O OD1 . ASP D 1 102 ? 106.741 162.023 105.221 1.00 78.87  ? 176 ASP D OD1 1 
ATOM 7398 O OD2 . ASP D 1 102 ? 104.602 162.486 105.049 1.00 81.52  ? 176 ASP D OD2 1 
ATOM 7399 N N   . PHE D 1 103 ? 105.311 157.273 106.796 1.00 59.38  ? 177 PHE D N   1 
ATOM 7400 C CA  . PHE D 1 103 ? 104.975 156.239 107.763 1.00 59.60  ? 177 PHE D CA  1 
ATOM 7401 C C   . PHE D 1 103 ? 104.742 154.931 107.022 1.00 64.64  ? 177 PHE D C   1 
ATOM 7402 O O   . PHE D 1 103 ? 104.202 154.920 105.913 1.00 73.34  ? 177 PHE D O   1 
ATOM 7403 C CB  . PHE D 1 103 ? 103.744 156.637 108.584 1.00 63.52  ? 177 PHE D CB  1 
ATOM 7404 C CG  . PHE D 1 103 ? 103.262 155.570 109.519 1.00 65.47  ? 177 PHE D CG  1 
ATOM 7405 C CD1 . PHE D 1 103 ? 104.073 155.112 110.543 1.00 70.08  ? 177 PHE D CD1 1 
ATOM 7406 C CD2 . PHE D 1 103 ? 101.992 155.041 109.388 1.00 66.48  ? 177 PHE D CD2 1 
ATOM 7407 C CE1 . PHE D 1 103 ? 103.630 154.134 111.410 1.00 73.10  ? 177 PHE D CE1 1 
ATOM 7408 C CE2 . PHE D 1 103 ? 101.543 154.065 110.252 1.00 70.36  ? 177 PHE D CE2 1 
ATOM 7409 C CZ  . PHE D 1 103 ? 102.364 153.610 111.264 1.00 75.04  ? 177 PHE D CZ  1 
ATOM 7410 N N   . ILE D 1 104 ? 105.153 153.829 107.647 1.00 58.88  ? 178 ILE D N   1 
ATOM 7411 C CA  . ILE D 1 104 ? 105.127 152.508 107.031 1.00 57.03  ? 178 ILE D CA  1 
ATOM 7412 C C   . ILE D 1 104 ? 104.216 151.599 107.842 1.00 59.57  ? 178 ILE D C   1 
ATOM 7413 O O   . ILE D 1 104 ? 104.330 151.533 109.071 1.00 66.53  ? 178 ILE D O   1 
ATOM 7414 C CB  . ILE D 1 104 ? 106.538 151.901 106.928 1.00 51.57  ? 178 ILE D CB  1 
ATOM 7415 C CG1 . ILE D 1 104 ? 107.443 152.788 106.080 1.00 56.02  ? 178 ILE D CG1 1 
ATOM 7416 C CG2 . ILE D 1 104 ? 106.481 150.507 106.340 1.00 56.80  ? 178 ILE D CG2 1 
ATOM 7417 C CD1 . ILE D 1 104 ? 108.841 152.243 105.922 1.00 60.36  ? 178 ILE D CD1 1 
ATOM 7418 N N   . ILE D 1 105 ? 103.314 150.905 107.154 1.00 56.47  ? 179 ILE D N   1 
ATOM 7419 C CA  . ILE D 1 105 ? 102.485 149.860 107.740 1.00 49.10  ? 179 ILE D CA  1 
ATOM 7420 C C   . ILE D 1 105 ? 102.874 148.544 107.086 1.00 54.76  ? 179 ILE D C   1 
ATOM 7421 O O   . ILE D 1 105 ? 102.918 148.450 105.854 1.00 68.34  ? 179 ILE D O   1 
ATOM 7422 C CB  . ILE D 1 105 ? 100.985 150.139 107.549 1.00 61.12  ? 179 ILE D CB  1 
ATOM 7423 C CG1 . ILE D 1 105 ? 100.600 151.463 108.208 1.00 67.20  ? 179 ILE D CG1 1 
ATOM 7424 C CG2 . ILE D 1 105 ? 100.163 149.004 108.125 1.00 62.93  ? 179 ILE D CG2 1 
ATOM 7425 C CD1 . ILE D 1 105 ? 99.129  151.799 108.088 1.00 68.21  ? 179 ILE D CD1 1 
ATOM 7426 N N   . CYS D 1 106 ? 103.152 147.534 107.902 1.00 58.89  ? 180 CYS D N   1 
ATOM 7427 C CA  . CYS D 1 106 ? 103.688 146.268 107.426 1.00 60.14  ? 180 CYS D CA  1 
ATOM 7428 C C   . CYS D 1 106 ? 102.736 145.136 107.778 1.00 65.47  ? 180 CYS D C   1 
ATOM 7429 O O   . CYS D 1 106 ? 102.186 145.101 108.883 1.00 71.12  ? 180 CYS D O   1 
ATOM 7430 C CB  . CYS D 1 106 ? 105.068 146.003 108.030 1.00 67.43  ? 180 CYS D CB  1 
ATOM 7431 S SG  . CYS D 1 106 ? 106.420 146.843 107.178 1.00 83.79  ? 180 CYS D SG  1 
ATOM 7432 N N   . LEU D 1 107 ? 102.545 144.219 106.835 1.00 87.23  ? 181 LEU D N   1 
ATOM 7433 C CA  . LEU D 1 107 ? 101.753 143.015 107.039 1.00 89.46  ? 181 LEU D CA  1 
ATOM 7434 C C   . LEU D 1 107 ? 102.640 141.803 106.796 1.00 91.06  ? 181 LEU D C   1 
ATOM 7435 O O   . LEU D 1 107 ? 103.303 141.715 105.757 1.00 90.71  ? 181 LEU D O   1 
ATOM 7436 C CB  . LEU D 1 107 ? 100.542 142.986 106.105 1.00 88.66  ? 181 LEU D CB  1 
ATOM 7437 C CG  . LEU D 1 107 ? 99.492  144.077 106.317 1.00 88.18  ? 181 LEU D CG  1 
ATOM 7438 C CD1 . LEU D 1 107 ? 98.304  143.858 105.397 1.00 85.58  ? 181 LEU D CD1 1 
ATOM 7439 C CD2 . LEU D 1 107 ? 99.049  144.120 107.770 1.00 88.19  ? 181 LEU D CD2 1 
ATOM 7440 N N   . GLY D 1 108 ? 102.653 140.879 107.745 1.00 97.33  ? 182 GLY D N   1 
ATOM 7441 C CA  . GLY D 1 108 ? 103.482 139.693 107.668 1.00 96.12  ? 182 GLY D CA  1 
ATOM 7442 C C   . GLY D 1 108 ? 104.345 139.522 108.906 1.00 97.04  ? 182 GLY D C   1 
ATOM 7443 O O   . GLY D 1 108 ? 104.394 140.369 109.795 1.00 97.37  ? 182 GLY D O   1 
ATOM 7444 N N   . GLY D 1 109 ? 105.035 138.385 108.938 1.00 101.05 ? 183 GLY D N   1 
ATOM 7445 C CA  . GLY D 1 109 ? 105.840 138.037 110.092 1.00 102.33 ? 183 GLY D CA  1 
ATOM 7446 C C   . GLY D 1 109 ? 107.337 137.998 109.859 1.00 103.62 ? 183 GLY D C   1 
ATOM 7447 O O   . GLY D 1 109 ? 107.843 137.104 109.174 1.00 104.39 ? 183 GLY D O   1 
ATOM 7448 N N   . ASP D 1 110 ? 108.049 138.983 110.413 1.00 98.58  ? 184 ASP D N   1 
ATOM 7449 C CA  . ASP D 1 110 ? 109.507 138.979 110.512 1.00 96.60  ? 184 ASP D CA  1 
ATOM 7450 C C   . ASP D 1 110 ? 110.216 139.010 109.162 1.00 96.26  ? 184 ASP D C   1 
ATOM 7451 O O   . ASP D 1 110 ? 111.450 138.995 109.110 1.00 98.92  ? 184 ASP D O   1 
ATOM 7452 C CB  . ASP D 1 110 ? 109.979 137.763 111.314 1.00 96.77  ? 184 ASP D CB  1 
ATOM 7453 C CG  . ASP D 1 110 ? 109.461 137.767 112.738 1.00 97.33  ? 184 ASP D CG  1 
ATOM 7454 O OD1 . ASP D 1 110 ? 109.239 138.866 113.288 1.00 94.83  ? 184 ASP D OD1 1 
ATOM 7455 O OD2 . ASP D 1 110 ? 109.278 136.671 113.308 1.00 98.70  ? 184 ASP D OD2 1 
ATOM 7456 N N   . GLY D 1 111 ? 109.462 139.055 108.068 1.00 76.33  ? 185 GLY D N   1 
ATOM 7457 C CA  . GLY D 1 111 ? 110.062 139.162 106.753 1.00 70.79  ? 185 GLY D CA  1 
ATOM 7458 C C   . GLY D 1 111 ? 109.694 140.470 106.093 1.00 70.26  ? 185 GLY D C   1 
ATOM 7459 O O   . GLY D 1 111 ? 110.462 141.032 105.302 1.00 70.47  ? 185 GLY D O   1 
ATOM 7460 N N   . THR D 1 112 ? 108.506 140.970 106.432 1.00 70.06  ? 186 THR D N   1 
ATOM 7461 C CA  . THR D 1 112 ? 108.039 142.220 105.851 1.00 71.37  ? 186 THR D CA  1 
ATOM 7462 C C   . THR D 1 112 ? 108.913 143.388 106.290 1.00 70.84  ? 186 THR D C   1 
ATOM 7463 O O   . THR D 1 112 ? 109.209 144.285 105.493 1.00 70.88  ? 186 THR D O   1 
ATOM 7464 C CB  . THR D 1 112 ? 106.579 142.460 106.230 1.00 70.46  ? 186 THR D CB  1 
ATOM 7465 O OG1 . THR D 1 112 ? 105.791 141.345 105.798 1.00 72.77  ? 186 THR D OG1 1 
ATOM 7466 C CG2 . THR D 1 112 ? 106.059 143.704 105.540 1.00 70.60  ? 186 THR D CG2 1 
ATOM 7467 N N   . LEU D 1 113 ? 109.351 143.392 107.553 1.00 72.52  ? 187 LEU D N   1 
ATOM 7468 C CA  . LEU D 1 113 ? 110.244 144.455 108.001 1.00 71.69  ? 187 LEU D CA  1 
ATOM 7469 C C   . LEU D 1 113 ? 111.621 144.334 107.368 1.00 73.95  ? 187 LEU D C   1 
ATOM 7470 O O   . LEU D 1 113 ? 112.273 145.352 107.116 1.00 74.54  ? 187 LEU D O   1 
ATOM 7471 C CB  . LEU D 1 113 ? 110.368 144.470 109.523 1.00 61.84  ? 187 LEU D CB  1 
ATOM 7472 C CG  . LEU D 1 113 ? 109.207 145.125 110.273 1.00 64.73  ? 187 LEU D CG  1 
ATOM 7473 C CD1 . LEU D 1 113 ? 107.982 144.224 110.286 1.00 66.83  ? 187 LEU D CD1 1 
ATOM 7474 C CD2 . LEU D 1 113 ? 109.610 145.543 111.677 1.00 71.43  ? 187 LEU D CD2 1 
ATOM 7475 N N   . LEU D 1 114 ? 112.083 143.111 107.107 1.00 69.16  ? 188 LEU D N   1 
ATOM 7476 C CA  . LEU D 1 114 ? 113.322 142.949 106.355 1.00 64.55  ? 188 LEU D CA  1 
ATOM 7477 C C   . LEU D 1 114 ? 113.192 143.545 104.961 1.00 63.44  ? 188 LEU D C   1 
ATOM 7478 O O   . LEU D 1 114 ? 114.095 144.248 104.491 1.00 64.55  ? 188 LEU D O   1 
ATOM 7479 C CB  . LEU D 1 114 ? 113.702 141.472 106.277 1.00 65.53  ? 188 LEU D CB  1 
ATOM 7480 C CG  . LEU D 1 114 ? 114.201 140.869 107.587 1.00 64.79  ? 188 LEU D CG  1 
ATOM 7481 C CD1 . LEU D 1 114 ? 114.553 139.404 107.405 1.00 62.33  ? 188 LEU D CD1 1 
ATOM 7482 C CD2 . LEU D 1 114 ? 115.399 141.658 108.081 1.00 65.93  ? 188 LEU D CD2 1 
ATOM 7483 N N   . TYR D 1 115 ? 112.067 143.288 104.291 1.00 52.15  ? 189 TYR D N   1 
ATOM 7484 C CA  . TYR D 1 115 ? 111.848 143.882 102.976 1.00 52.71  ? 189 TYR D CA  1 
ATOM 7485 C C   . TYR D 1 115 ? 111.787 145.403 103.062 1.00 58.64  ? 189 TYR D C   1 
ATOM 7486 O O   . TYR D 1 115 ? 112.336 146.104 102.203 1.00 63.92  ? 189 TYR D O   1 
ATOM 7487 C CB  . TYR D 1 115 ? 110.568 143.328 102.355 1.00 54.15  ? 189 TYR D CB  1 
ATOM 7488 C CG  . TYR D 1 115 ? 110.271 143.880 100.983 1.00 53.11  ? 189 TYR D CG  1 
ATOM 7489 C CD1 . TYR D 1 115 ? 110.886 143.359 99.857  1.00 56.54  ? 189 TYR D CD1 1 
ATOM 7490 C CD2 . TYR D 1 115 ? 109.376 144.924 100.814 1.00 51.17  ? 189 TYR D CD2 1 
ATOM 7491 C CE1 . TYR D 1 115 ? 110.617 143.862 98.602  1.00 59.71  ? 189 TYR D CE1 1 
ATOM 7492 C CE2 . TYR D 1 115 ? 109.102 145.434 99.568  1.00 51.86  ? 189 TYR D CE2 1 
ATOM 7493 C CZ  . TYR D 1 115 ? 109.723 144.900 98.464  1.00 59.38  ? 189 TYR D CZ  1 
ATOM 7494 O OH  . TYR D 1 115 ? 109.450 145.408 97.215  1.00 62.99  ? 189 TYR D OH  1 
ATOM 7495 N N   . ALA D 1 116 ? 111.120 145.930 104.092 1.00 56.69  ? 190 ALA D N   1 
ATOM 7496 C CA  . ALA D 1 116 ? 111.016 147.377 104.248 1.00 57.64  ? 190 ALA D CA  1 
ATOM 7497 C C   . ALA D 1 116 ? 112.383 148.010 104.479 1.00 56.94  ? 190 ALA D C   1 
ATOM 7498 O O   . ALA D 1 116 ? 112.691 149.064 103.911 1.00 58.21  ? 190 ALA D O   1 
ATOM 7499 C CB  . ALA D 1 116 ? 110.066 147.715 105.395 1.00 58.85  ? 190 ALA D CB  1 
ATOM 7500 N N   . SER D 1 117 ? 113.213 147.383 105.314 1.00 61.85  ? 191 SER D N   1 
ATOM 7501 C CA  . SER D 1 117 ? 114.562 147.889 105.540 1.00 61.53  ? 191 SER D CA  1 
ATOM 7502 C C   . SER D 1 117 ? 115.392 147.819 104.268 1.00 64.17  ? 191 SER D C   1 
ATOM 7503 O O   . SER D 1 117 ? 116.189 148.723 103.989 1.00 67.26  ? 191 SER D O   1 
ATOM 7504 C CB  . SER D 1 117 ? 115.240 147.106 106.662 1.00 56.08  ? 191 SER D CB  1 
ATOM 7505 O OG  . SER D 1 117 ? 115.354 145.735 106.326 1.00 59.79  ? 191 SER D OG  1 
ATOM 7506 N N   . SER D 1 118 ? 115.227 146.749 103.487 1.00 62.64  ? 192 SER D N   1 
ATOM 7507 C CA  . SER D 1 118 ? 115.933 146.654 102.215 1.00 61.80  ? 192 SER D CA  1 
ATOM 7508 C C   . SER D 1 118 ? 115.517 147.776 101.277 1.00 61.16  ? 192 SER D C   1 
ATOM 7509 O O   . SER D 1 118 ? 116.353 148.341 100.561 1.00 66.56  ? 192 SER D O   1 
ATOM 7510 C CB  . SER D 1 118 ? 115.672 145.297 101.566 1.00 64.93  ? 192 SER D CB  1 
ATOM 7511 O OG  . SER D 1 118 ? 114.303 145.151 101.235 1.00 67.12  ? 192 SER D OG  1 
ATOM 7512 N N   . LEU D 1 119 ? 114.228 148.115 101.267 1.00 57.00  ? 193 LEU D N   1 
ATOM 7513 C CA  . LEU D 1 119 ? 113.743 149.147 100.361 1.00 62.48  ? 193 LEU D CA  1 
ATOM 7514 C C   . LEU D 1 119 ? 114.144 150.548 100.811 1.00 61.03  ? 193 LEU D C   1 
ATOM 7515 O O   . LEU D 1 119 ? 114.180 151.464 99.982  1.00 61.65  ? 193 LEU D O   1 
ATOM 7516 C CB  . LEU D 1 119 ? 112.223 149.036 100.223 1.00 58.01  ? 193 LEU D CB  1 
ATOM 7517 C CG  . LEU D 1 119 ? 111.486 150.044 99.341  1.00 58.49  ? 193 LEU D CG  1 
ATOM 7518 C CD1 . LEU D 1 119 ? 111.920 149.903 97.892  1.00 61.56  ? 193 LEU D CD1 1 
ATOM 7519 C CD2 . LEU D 1 119 ? 109.983 149.869 99.473  1.00 61.04  ? 193 LEU D CD2 1 
ATOM 7520 N N   . PHE D 1 120 ? 114.471 150.732 102.088 1.00 55.24  ? 194 PHE D N   1 
ATOM 7521 C CA  . PHE D 1 120 ? 114.850 152.036 102.632 1.00 60.63  ? 194 PHE D CA  1 
ATOM 7522 C C   . PHE D 1 120 ? 116.280 151.956 103.159 1.00 64.79  ? 194 PHE D C   1 
ATOM 7523 O O   . PHE D 1 120 ? 116.510 151.511 104.288 1.00 58.56  ? 194 PHE D O   1 
ATOM 7524 C CB  . PHE D 1 120 ? 113.883 152.473 103.727 1.00 60.87  ? 194 PHE D CB  1 
ATOM 7525 C CG  . PHE D 1 120 ? 112.613 153.071 103.207 1.00 60.43  ? 194 PHE D CG  1 
ATOM 7526 C CD1 . PHE D 1 120 ? 112.595 154.360 102.708 1.00 62.22  ? 194 PHE D CD1 1 
ATOM 7527 C CD2 . PHE D 1 120 ? 111.439 152.343 103.207 1.00 58.09  ? 194 PHE D CD2 1 
ATOM 7528 C CE1 . PHE D 1 120 ? 111.429 154.911 102.226 1.00 58.00  ? 194 PHE D CE1 1 
ATOM 7529 C CE2 . PHE D 1 120 ? 110.272 152.889 102.723 1.00 61.53  ? 194 PHE D CE2 1 
ATOM 7530 C CZ  . PHE D 1 120 ? 110.266 154.173 102.233 1.00 59.89  ? 194 PHE D CZ  1 
ATOM 7531 N N   . GLN D 1 121 ? 117.237 152.396 102.344 1.00 66.51  ? 195 GLN D N   1 
ATOM 7532 C CA  . GLN D 1 121 ? 118.635 152.434 102.753 1.00 64.14  ? 195 GLN D CA  1 
ATOM 7533 C C   . GLN D 1 121 ? 118.997 153.702 103.514 1.00 61.29  ? 195 GLN D C   1 
ATOM 7534 O O   . GLN D 1 121 ? 120.091 153.768 104.086 1.00 66.35  ? 195 GLN D O   1 
ATOM 7535 C CB  . GLN D 1 121 ? 119.543 152.298 101.529 1.00 64.78  ? 195 GLN D CB  1 
ATOM 7536 C CG  . GLN D 1 121 ? 119.380 150.986 100.785 1.00 64.65  ? 195 GLN D CG  1 
ATOM 7537 C CD  . GLN D 1 121 ? 119.796 149.793 101.617 1.00 65.26  ? 195 GLN D CD  1 
ATOM 7538 O OE1 . GLN D 1 121 ? 120.985 149.525 101.785 1.00 64.74  ? 195 GLN D OE1 1 
ATOM 7539 N NE2 . GLN D 1 121 ? 118.817 149.071 102.148 1.00 62.44  ? 195 GLN D NE2 1 
ATOM 7540 N N   . GLY D 1 122 ? 118.120 154.700 103.535 1.00 50.70  ? 196 GLY D N   1 
ATOM 7541 C CA  . GLY D 1 122 ? 118.393 155.931 104.250 1.00 54.76  ? 196 GLY D CA  1 
ATOM 7542 C C   . GLY D 1 122 ? 117.644 156.022 105.562 1.00 64.20  ? 196 GLY D C   1 
ATOM 7543 O O   . GLY D 1 122 ? 117.566 155.040 106.306 1.00 68.68  ? 196 GLY D O   1 
ATOM 7544 N N   . SER D 1 123 ? 117.083 157.192 105.856 1.00 66.36  ? 197 SER D N   1 
ATOM 7545 C CA  . SER D 1 123 ? 116.330 157.404 107.090 1.00 61.88  ? 197 SER D CA  1 
ATOM 7546 C C   . SER D 1 123 ? 114.944 156.797 106.920 1.00 65.93  ? 197 SER D C   1 
ATOM 7547 O O   . SER D 1 123 ? 114.035 157.434 106.383 1.00 72.89  ? 197 SER D O   1 
ATOM 7548 C CB  . SER D 1 123 ? 116.251 158.889 107.422 1.00 63.17  ? 197 SER D CB  1 
ATOM 7549 O OG  . SER D 1 123 ? 115.603 159.608 106.387 1.00 71.10  ? 197 SER D OG  1 
ATOM 7550 N N   . VAL D 1 124 ? 114.780 155.563 107.377 1.00 54.78  ? 198 VAL D N   1 
ATOM 7551 C CA  . VAL D 1 124 ? 113.493 154.873 107.226 1.00 59.50  ? 198 VAL D CA  1 
ATOM 7552 C C   . VAL D 1 124 ? 112.473 155.495 108.174 1.00 60.89  ? 198 VAL D C   1 
ATOM 7553 O O   . VAL D 1 124 ? 112.813 155.808 109.329 1.00 62.41  ? 198 VAL D O   1 
ATOM 7554 C CB  . VAL D 1 124 ? 113.661 153.370 107.479 1.00 48.80  ? 198 VAL D CB  1 
ATOM 7555 C CG1 . VAL D 1 124 ? 114.110 153.102 108.897 1.00 51.50  ? 198 VAL D CG1 1 
ATOM 7556 C CG2 . VAL D 1 124 ? 112.373 152.623 107.182 1.00 51.99  ? 198 VAL D CG2 1 
ATOM 7557 N N   . PRO D 1 125 ? 111.243 155.736 107.730 1.00 58.73  ? 199 PRO D N   1 
ATOM 7558 C CA  . PRO D 1 125 ? 110.227 156.312 108.617 1.00 55.54  ? 199 PRO D CA  1 
ATOM 7559 C C   . PRO D 1 125 ? 109.753 155.290 109.635 1.00 57.38  ? 199 PRO D C   1 
ATOM 7560 O O   . PRO D 1 125 ? 110.148 154.116 109.570 1.00 64.97  ? 199 PRO D O   1 
ATOM 7561 C CB  . PRO D 1 125 ? 109.100 156.706 107.648 1.00 63.49  ? 199 PRO D CB  1 
ATOM 7562 C CG  . PRO D 1 125 ? 109.308 155.854 106.453 1.00 61.73  ? 199 PRO D CG  1 
ATOM 7563 C CD  . PRO D 1 125 ? 110.783 155.662 106.334 1.00 59.34  ? 199 PRO D CD  1 
ATOM 7564 N N   . PRO D 1 126 ? 108.925 155.695 110.600 1.00 51.18  ? 200 PRO D N   1 
ATOM 7565 C CA  . PRO D 1 126 ? 108.400 154.726 111.569 1.00 55.94  ? 200 PRO D CA  1 
ATOM 7566 C C   . PRO D 1 126 ? 107.648 153.595 110.886 1.00 59.00  ? 200 PRO D C   1 
ATOM 7567 O O   . PRO D 1 126 ? 106.925 153.802 109.909 1.00 65.51  ? 200 PRO D O   1 
ATOM 7568 C CB  . PRO D 1 126 ? 107.470 155.573 112.442 1.00 60.85  ? 200 PRO D CB  1 
ATOM 7569 C CG  . PRO D 1 126 ? 108.057 156.930 112.382 1.00 60.75  ? 200 PRO D CG  1 
ATOM 7570 C CD  . PRO D 1 126 ? 108.610 157.081 110.993 1.00 56.71  ? 200 PRO D CD  1 
ATOM 7571 N N   . VAL D 1 127 ? 107.825 152.389 111.415 1.00 59.90  ? 201 VAL D N   1 
ATOM 7572 C CA  . VAL D 1 127 ? 107.257 151.175 110.845 1.00 58.44  ? 201 VAL D CA  1 
ATOM 7573 C C   . VAL D 1 127 ? 106.369 150.519 111.889 1.00 56.94  ? 201 VAL D C   1 
ATOM 7574 O O   . VAL D 1 127 ? 106.812 150.261 113.014 1.00 70.40  ? 201 VAL D O   1 
ATOM 7575 C CB  . VAL D 1 127 ? 108.352 150.200 110.377 1.00 67.37  ? 201 VAL D CB  1 
ATOM 7576 C CG1 . VAL D 1 127 ? 107.731 149.007 109.680 1.00 68.15  ? 201 VAL D CG1 1 
ATOM 7577 C CG2 . VAL D 1 127 ? 109.333 150.904 109.455 1.00 68.34  ? 201 VAL D CG2 1 
ATOM 7578 N N   . MET D 1 128 ? 105.124 150.250 111.518 1.00 55.97  ? 202 MET D N   1 
ATOM 7579 C CA  . MET D 1 128 ? 104.181 149.540 112.367 1.00 64.66  ? 202 MET D CA  1 
ATOM 7580 C C   . MET D 1 128 ? 103.833 148.215 111.709 1.00 62.64  ? 202 MET D C   1 
ATOM 7581 O O   . MET D 1 128 ? 103.430 148.186 110.542 1.00 74.16  ? 202 MET D O   1 
ATOM 7582 C CB  . MET D 1 128 ? 102.916 150.368 112.599 1.00 72.39  ? 202 MET D CB  1 
ATOM 7583 C CG  . MET D 1 128 ? 101.866 149.663 113.439 1.00 76.87  ? 202 MET D CG  1 
ATOM 7584 S SD  . MET D 1 128 ? 100.475 150.727 113.867 1.00 89.48  ? 202 MET D SD  1 
ATOM 7585 C CE  . MET D 1 128 ? 99.927  151.239 112.243 1.00 70.33  ? 202 MET D CE  1 
ATOM 7586 N N   . ALA D 1 129 ? 103.985 147.127 112.453 1.00 45.89  ? 203 ALA D N   1 
ATOM 7587 C CA  . ALA D 1 129 ? 103.798 145.789 111.919 1.00 52.13  ? 203 ALA D CA  1 
ATOM 7588 C C   . ALA D 1 129 ? 102.618 145.108 112.592 1.00 59.45  ? 203 ALA D C   1 
ATOM 7589 O O   . ALA D 1 129 ? 102.432 145.221 113.808 1.00 64.21  ? 203 ALA D O   1 
ATOM 7590 C CB  . ALA D 1 129 ? 105.053 144.945 112.103 1.00 59.87  ? 203 ALA D CB  1 
ATOM 7591 N N   . PHE D 1 130 ? 101.825 144.402 111.792 1.00 63.85  ? 204 PHE D N   1 
ATOM 7592 C CA  . PHE D 1 130 ? 100.678 143.646 112.270 1.00 63.08  ? 204 PHE D CA  1 
ATOM 7593 C C   . PHE D 1 130 ? 100.937 142.164 112.052 1.00 66.56  ? 204 PHE D C   1 
ATOM 7594 O O   . PHE D 1 130 ? 101.408 141.766 110.982 1.00 68.03  ? 204 PHE D O   1 
ATOM 7595 C CB  . PHE D 1 130 ? 99.398  144.074 111.550 1.00 65.04  ? 204 PHE D CB  1 
ATOM 7596 C CG  . PHE D 1 130 ? 98.990  145.491 111.827 1.00 63.99  ? 204 PHE D CG  1 
ATOM 7597 C CD1 . PHE D 1 130 ? 99.520  146.537 111.096 1.00 66.78  ? 204 PHE D CD1 1 
ATOM 7598 C CD2 . PHE D 1 130 ? 98.071  145.775 112.820 1.00 67.49  ? 204 PHE D CD2 1 
ATOM 7599 C CE1 . PHE D 1 130 ? 99.143  147.839 111.354 1.00 67.50  ? 204 PHE D CE1 1 
ATOM 7600 C CE2 . PHE D 1 130 ? 97.691  147.074 113.080 1.00 66.63  ? 204 PHE D CE2 1 
ATOM 7601 C CZ  . PHE D 1 130 ? 98.227  148.106 112.348 1.00 64.80  ? 204 PHE D CZ  1 
ATOM 7602 N N   . HIS D 1 131 ? 100.634 141.351 113.062 1.00 86.63  ? 205 HIS D N   1 
ATOM 7603 C CA  . HIS D 1 131 ? 100.806 139.902 112.977 1.00 88.60  ? 205 HIS D CA  1 
ATOM 7604 C C   . HIS D 1 131 ? 99.434  139.276 112.752 1.00 88.81  ? 205 HIS D C   1 
ATOM 7605 O O   . HIS D 1 131 ? 98.557  139.335 113.617 1.00 86.52  ? 205 HIS D O   1 
ATOM 7606 C CB  . HIS D 1 131 ? 101.484 139.346 114.226 1.00 87.62  ? 205 HIS D CB  1 
ATOM 7607 C CG  . HIS D 1 131 ? 100.739 139.611 115.497 1.00 87.80  ? 205 HIS D CG  1 
ATOM 7608 N ND1 . HIS D 1 131 ? 100.762 140.833 116.134 1.00 91.23  ? 205 HIS D ND1 1 
ATOM 7609 C CD2 . HIS D 1 131 ? 99.956  138.807 116.252 1.00 89.67  ? 205 HIS D CD2 1 
ATOM 7610 C CE1 . HIS D 1 131 ? 100.023 140.769 117.228 1.00 90.61  ? 205 HIS D CE1 1 
ATOM 7611 N NE2 . HIS D 1 131 ? 99.520  139.552 117.321 1.00 89.96  ? 205 HIS D NE2 1 
ATOM 7612 N N   . LEU D 1 132 ? 99.247  138.684 111.572 1.00 103.11 ? 206 LEU D N   1 
ATOM 7613 C CA  . LEU D 1 132 ? 97.990  138.025 111.222 1.00 102.74 ? 206 LEU D CA  1 
ATOM 7614 C C   . LEU D 1 132 ? 98.184  136.521 111.382 1.00 104.45 ? 206 LEU D C   1 
ATOM 7615 O O   . LEU D 1 132 ? 98.494  135.790 110.438 1.00 104.01 ? 206 LEU D O   1 
ATOM 7616 C CB  . LEU D 1 132 ? 97.559  138.400 109.810 1.00 102.22 ? 206 LEU D CB  1 
ATOM 7617 C CG  . LEU D 1 132 ? 97.100  139.844 109.592 1.00 100.75 ? 206 LEU D CG  1 
ATOM 7618 C CD1 . LEU D 1 132 ? 98.278  140.783 109.367 1.00 100.49 ? 206 LEU D CD1 1 
ATOM 7619 C CD2 . LEU D 1 132 ? 96.131  139.917 108.432 1.00 100.19 ? 206 LEU D CD2 1 
ATOM 7620 N N   . GLY D 1 133 ? 97.990  136.055 112.613 1.00 110.90 ? 207 GLY D N   1 
ATOM 7621 C CA  . GLY D 1 133 ? 98.242  134.665 112.937 1.00 110.39 ? 207 GLY D CA  1 
ATOM 7622 C C   . GLY D 1 133 ? 99.507  134.489 113.751 1.00 111.78 ? 207 GLY D C   1 
ATOM 7623 O O   . GLY D 1 133 ? 99.518  134.756 114.957 1.00 111.04 ? 207 GLY D O   1 
ATOM 7624 N N   . SER D 1 134 ? 100.575 134.032 113.105 1.00 110.54 ? 208 SER D N   1 
ATOM 7625 C CA  . SER D 1 134 ? 101.852 133.873 113.786 1.00 109.40 ? 208 SER D CA  1 
ATOM 7626 C C   . SER D 1 134 ? 102.394 135.227 114.228 1.00 107.97 ? 208 SER D C   1 
ATOM 7627 O O   . SER D 1 134 ? 102.324 136.215 113.491 1.00 108.28 ? 208 SER D O   1 
ATOM 7628 C CB  . SER D 1 134 ? 102.859 133.177 112.872 1.00 108.64 ? 208 SER D CB  1 
ATOM 7629 O OG  . SER D 1 134 ? 103.055 133.913 111.676 1.00 109.13 ? 208 SER D OG  1 
ATOM 7630 N N   . LEU D 1 135 ? 102.939 135.267 115.439 1.00 98.62  ? 209 LEU D N   1 
ATOM 7631 C CA  . LEU D 1 135 ? 103.482 136.483 116.028 1.00 99.84  ? 209 LEU D CA  1 
ATOM 7632 C C   . LEU D 1 135 ? 105.000 136.395 116.042 1.00 100.74 ? 209 LEU D C   1 
ATOM 7633 O O   . LEU D 1 135 ? 105.562 135.380 116.466 1.00 100.29 ? 209 LEU D O   1 
ATOM 7634 C CB  . LEU D 1 135 ? 102.938 136.691 117.445 1.00 101.36 ? 209 LEU D CB  1 
ATOM 7635 C CG  . LEU D 1 135 ? 103.364 137.935 118.230 1.00 101.44 ? 209 LEU D CG  1 
ATOM 7636 C CD1 . LEU D 1 135 ? 102.202 138.449 119.062 1.00 100.12 ? 209 LEU D CD1 1 
ATOM 7637 C CD2 . LEU D 1 135 ? 104.557 137.636 119.127 1.00 99.60  ? 209 LEU D CD2 1 
ATOM 7638 N N   . GLY D 1 136 ? 105.660 137.456 115.574 1.00 92.56  ? 210 GLY D N   1 
ATOM 7639 C CA  . GLY D 1 136 ? 107.095 137.522 115.527 1.00 90.69  ? 210 GLY D CA  1 
ATOM 7640 C C   . GLY D 1 136 ? 107.671 138.500 116.529 1.00 92.07  ? 210 GLY D C   1 
ATOM 7641 O O   . GLY D 1 136 ? 106.970 139.039 117.395 1.00 93.47  ? 210 GLY D O   1 
ATOM 7642 N N   . PHE D 1 137 ? 108.977 138.735 116.409 1.00 86.18  ? 211 PHE D N   1 
ATOM 7643 C CA  . PHE D 1 137 ? 109.669 139.655 117.299 1.00 83.87  ? 211 PHE D CA  1 
ATOM 7644 C C   . PHE D 1 137 ? 109.538 141.106 116.870 1.00 84.24  ? 211 PHE D C   1 
ATOM 7645 O O   . PHE D 1 137 ? 109.840 142.003 117.665 1.00 86.11  ? 211 PHE D O   1 
ATOM 7646 C CB  . PHE D 1 137 ? 111.154 139.293 117.387 1.00 82.38  ? 211 PHE D CB  1 
ATOM 7647 C CG  . PHE D 1 137 ? 111.410 137.925 117.939 1.00 82.75  ? 211 PHE D CG  1 
ATOM 7648 C CD1 . PHE D 1 137 ? 111.461 137.712 119.304 1.00 84.54  ? 211 PHE D CD1 1 
ATOM 7649 C CD2 . PHE D 1 137 ? 111.601 136.850 117.090 1.00 83.41  ? 211 PHE D CD2 1 
ATOM 7650 C CE1 . PHE D 1 137 ? 111.694 136.451 119.812 1.00 86.63  ? 211 PHE D CE1 1 
ATOM 7651 C CE2 . PHE D 1 137 ? 111.837 135.588 117.591 1.00 84.25  ? 211 PHE D CE2 1 
ATOM 7652 C CZ  . PHE D 1 137 ? 111.883 135.389 118.952 1.00 85.17  ? 211 PHE D CZ  1 
ATOM 7653 N N   . LEU D 1 138 ? 109.102 141.357 115.639 1.00 79.41  ? 212 LEU D N   1 
ATOM 7654 C CA  . LEU D 1 138 ? 109.011 142.704 115.099 1.00 80.77  ? 212 LEU D CA  1 
ATOM 7655 C C   . LEU D 1 138 ? 107.581 143.109 114.766 1.00 86.83  ? 212 LEU D C   1 
ATOM 7656 O O   . LEU D 1 138 ? 107.374 144.155 114.143 1.00 87.66  ? 212 LEU D O   1 
ATOM 7657 C CB  . LEU D 1 138 ? 109.894 142.823 113.858 1.00 82.03  ? 212 LEU D CB  1 
ATOM 7658 C CG  . LEU D 1 138 ? 111.310 142.259 113.983 1.00 82.38  ? 212 LEU D CG  1 
ATOM 7659 C CD1 . LEU D 1 138 ? 112.030 142.310 112.645 1.00 83.75  ? 212 LEU D CD1 1 
ATOM 7660 C CD2 . LEU D 1 138 ? 112.093 143.009 115.046 1.00 83.03  ? 212 LEU D CD2 1 
ATOM 7661 N N   . THR D 1 139 ? 106.590 142.314 115.172 1.00 87.71  ? 213 THR D N   1 
ATOM 7662 C CA  . THR D 1 139 ? 105.185 142.546 114.834 1.00 82.55  ? 213 THR D CA  1 
ATOM 7663 C C   . THR D 1 139 ? 104.373 142.593 116.121 1.00 76.34  ? 213 THR D C   1 
ATOM 7664 O O   . THR D 1 139 ? 103.731 141.605 116.504 1.00 79.24  ? 213 THR D O   1 
ATOM 7665 C CB  . THR D 1 139 ? 104.653 141.460 113.897 1.00 84.77  ? 213 THR D CB  1 
ATOM 7666 O OG1 . THR D 1 139 ? 104.656 140.200 114.578 1.00 86.97  ? 213 THR D OG1 1 
ATOM 7667 C CG2 . THR D 1 139 ? 105.521 141.354 112.655 1.00 81.50  ? 213 THR D CG2 1 
ATOM 7668 N N   . PRO D 1 140 ? 104.379 143.726 116.815 1.00 74.34  ? 214 PRO D N   1 
ATOM 7669 C CA  . PRO D 1 140 ? 103.704 143.796 118.118 1.00 82.56  ? 214 PRO D CA  1 
ATOM 7670 C C   . PRO D 1 140 ? 102.195 143.976 118.036 1.00 85.95  ? 214 PRO D C   1 
ATOM 7671 O O   . PRO D 1 140 ? 101.463 143.440 118.874 1.00 86.65  ? 214 PRO D O   1 
ATOM 7672 C CB  . PRO D 1 140 ? 104.369 145.009 118.778 1.00 82.93  ? 214 PRO D CB  1 
ATOM 7673 C CG  . PRO D 1 140 ? 104.731 145.885 117.632 1.00 83.53  ? 214 PRO D CG  1 
ATOM 7674 C CD  . PRO D 1 140 ? 105.105 144.967 116.499 1.00 78.23  ? 214 PRO D CD  1 
ATOM 7675 N N   . PHE D 1 141 ? 101.714 144.719 117.044 1.00 79.91  ? 215 PHE D N   1 
ATOM 7676 C CA  . PHE D 1 141 ? 100.309 145.106 117.006 1.00 75.57  ? 215 PHE D CA  1 
ATOM 7677 C C   . PHE D 1 141 ? 99.428  143.969 116.506 1.00 75.19  ? 215 PHE D C   1 
ATOM 7678 O O   . PHE D 1 141 ? 99.772  143.268 115.551 1.00 78.63  ? 215 PHE D O   1 
ATOM 7679 C CB  . PHE D 1 141 ? 100.117 146.334 116.119 1.00 74.64  ? 215 PHE D CB  1 
ATOM 7680 C CG  . PHE D 1 141 ? 100.588 147.611 116.745 1.00 71.95  ? 215 PHE D CG  1 
ATOM 7681 C CD1 . PHE D 1 141 ? 101.888 148.042 116.574 1.00 71.75  ? 215 PHE D CD1 1 
ATOM 7682 C CD2 . PHE D 1 141 ? 99.727  148.380 117.506 1.00 77.57  ? 215 PHE D CD2 1 
ATOM 7683 C CE1 . PHE D 1 141 ? 102.323 149.217 117.146 1.00 75.38  ? 215 PHE D CE1 1 
ATOM 7684 C CE2 . PHE D 1 141 ? 100.155 149.556 118.083 1.00 79.01  ? 215 PHE D CE2 1 
ATOM 7685 C CZ  . PHE D 1 141 ? 101.455 149.975 117.903 1.00 80.18  ? 215 PHE D CZ  1 
ATOM 7686 N N   . SER D 1 142 ? 98.281  143.802 117.156 1.00 77.85  ? 216 SER D N   1 
ATOM 7687 C CA  . SER D 1 142 ? 97.285  142.824 116.748 1.00 82.19  ? 216 SER D CA  1 
ATOM 7688 C C   . SER D 1 142 ? 96.276  143.471 115.809 1.00 85.15  ? 216 SER D C   1 
ATOM 7689 O O   . SER D 1 142 ? 96.017  144.675 115.878 1.00 85.95  ? 216 SER D O   1 
ATOM 7690 C CB  . SER D 1 142 ? 96.567  142.240 117.966 1.00 85.83  ? 216 SER D CB  1 
ATOM 7691 O OG  . SER D 1 142 ? 95.685  141.198 117.587 1.00 88.64  ? 216 SER D OG  1 
ATOM 7692 N N   . PHE D 1 143 ? 95.703  142.655 114.923 1.00 95.72  ? 217 PHE D N   1 
ATOM 7693 C CA  . PHE D 1 143 ? 94.823  143.190 113.893 1.00 95.17  ? 217 PHE D CA  1 
ATOM 7694 C C   . PHE D 1 143 ? 93.425  143.509 114.404 1.00 97.51  ? 217 PHE D C   1 
ATOM 7695 O O   . PHE D 1 143 ? 92.692  144.247 113.737 1.00 98.96  ? 217 PHE D O   1 
ATOM 7696 C CB  . PHE D 1 143 ? 94.729  142.220 112.714 1.00 96.46  ? 217 PHE D CB  1 
ATOM 7697 C CG  . PHE D 1 143 ? 94.124  142.830 111.485 1.00 98.09  ? 217 PHE D CG  1 
ATOM 7698 C CD1 . PHE D 1 143 ? 94.858  143.700 110.697 1.00 95.78  ? 217 PHE D CD1 1 
ATOM 7699 C CD2 . PHE D 1 143 ? 92.818  142.545 111.122 1.00 97.76  ? 217 PHE D CD2 1 
ATOM 7700 C CE1 . PHE D 1 143 ? 94.305  144.270 109.571 1.00 96.15  ? 217 PHE D CE1 1 
ATOM 7701 C CE2 . PHE D 1 143 ? 92.259  143.114 109.994 1.00 96.83  ? 217 PHE D CE2 1 
ATOM 7702 C CZ  . PHE D 1 143 ? 93.005  143.978 109.219 1.00 96.71  ? 217 PHE D CZ  1 
ATOM 7703 N N   . GLU D 1 144 ? 93.036  142.983 115.562 1.00 103.17 ? 218 GLU D N   1 
ATOM 7704 C CA  . GLU D 1 144 ? 91.723  143.294 116.107 1.00 102.48 ? 218 GLU D CA  1 
ATOM 7705 C C   . GLU D 1 144 ? 91.646  144.768 116.488 1.00 102.11 ? 218 GLU D C   1 
ATOM 7706 O O   . GLU D 1 144 ? 92.588  145.329 117.056 1.00 102.48 ? 218 GLU D O   1 
ATOM 7707 C CB  . GLU D 1 144 ? 91.422  142.407 117.316 1.00 102.52 ? 218 GLU D CB  1 
ATOM 7708 C CG  . GLU D 1 144 ? 92.502  142.397 118.391 1.00 103.80 ? 218 GLU D CG  1 
ATOM 7709 C CD  . GLU D 1 144 ? 92.307  143.482 119.432 1.00 104.46 ? 218 GLU D CD  1 
ATOM 7710 O OE1 . GLU D 1 144 ? 91.197  144.052 119.500 1.00 104.52 ? 218 GLU D OE1 1 
ATOM 7711 O OE2 . GLU D 1 144 ? 93.263  143.765 120.183 1.00 101.73 ? 218 GLU D OE2 1 
ATOM 7712 N N   . ASN D 1 145 ? 90.516  145.394 116.161 1.00 95.78  ? 219 ASN D N   1 
ATOM 7713 C CA  . ASN D 1 145 ? 90.310  146.826 116.375 1.00 95.88  ? 219 ASN D CA  1 
ATOM 7714 C C   . ASN D 1 145 ? 91.439  147.638 115.745 1.00 94.81  ? 219 ASN D C   1 
ATOM 7715 O O   . ASN D 1 145 ? 92.013  148.540 116.358 1.00 94.54  ? 219 ASN D O   1 
ATOM 7716 C CB  . ASN D 1 145 ? 90.166  147.145 117.864 1.00 96.46  ? 219 ASN D CB  1 
ATOM 7717 C CG  . ASN D 1 145 ? 89.568  148.516 118.111 1.00 97.31  ? 219 ASN D CG  1 
ATOM 7718 O OD1 . ASN D 1 145 ? 88.993  149.126 117.210 1.00 96.69  ? 219 ASN D OD1 1 
ATOM 7719 N ND2 . ASN D 1 145 ? 89.701  149.008 119.337 1.00 97.40  ? 219 ASN D ND2 1 
ATOM 7720 N N   . PHE D 1 146 ? 91.762  147.301 114.494 1.00 93.89  ? 220 PHE D N   1 
ATOM 7721 C CA  . PHE D 1 146 ? 92.882  147.952 113.826 1.00 94.53  ? 220 PHE D CA  1 
ATOM 7722 C C   . PHE D 1 146 ? 92.615  149.428 113.568 1.00 95.73  ? 220 PHE D C   1 
ATOM 7723 O O   . PHE D 1 146 ? 93.559  150.226 113.548 1.00 97.11  ? 220 PHE D O   1 
ATOM 7724 C CB  . PHE D 1 146 ? 93.216  147.228 112.521 1.00 95.13  ? 220 PHE D CB  1 
ATOM 7725 C CG  . PHE D 1 146 ? 92.201  147.425 111.432 1.00 95.75  ? 220 PHE D CG  1 
ATOM 7726 C CD1 . PHE D 1 146 ? 91.077  146.620 111.364 1.00 97.03  ? 220 PHE D CD1 1 
ATOM 7727 C CD2 . PHE D 1 146 ? 92.377  148.403 110.469 1.00 96.10  ? 220 PHE D CD2 1 
ATOM 7728 C CE1 . PHE D 1 146 ? 90.145  146.791 110.360 1.00 98.27  ? 220 PHE D CE1 1 
ATOM 7729 C CE2 . PHE D 1 146 ? 91.447  148.582 109.465 1.00 97.26  ? 220 PHE D CE2 1 
ATOM 7730 C CZ  . PHE D 1 146 ? 90.329  147.775 109.410 1.00 97.81  ? 220 PHE D CZ  1 
ATOM 7731 N N   . GLN D 1 147 ? 91.353  149.814 113.366 1.00 99.21  ? 221 GLN D N   1 
ATOM 7732 C CA  . GLN D 1 147 ? 91.049  151.216 113.097 1.00 98.39  ? 221 GLN D CA  1 
ATOM 7733 C C   . GLN D 1 147 ? 91.469  152.100 114.264 1.00 97.36  ? 221 GLN D C   1 
ATOM 7734 O O   . GLN D 1 147 ? 92.097  153.148 114.070 1.00 99.21  ? 221 GLN D O   1 
ATOM 7735 C CB  . GLN D 1 147 ? 89.557  151.395 112.808 1.00 96.03  ? 221 GLN D CB  1 
ATOM 7736 C CG  . GLN D 1 147 ? 89.025  150.593 111.633 1.00 94.91  ? 221 GLN D CG  1 
ATOM 7737 C CD  . GLN D 1 147 ? 88.528  149.221 112.042 1.00 97.89  ? 221 GLN D CD  1 
ATOM 7738 O OE1 . GLN D 1 147 ? 88.880  148.712 113.107 1.00 98.60  ? 221 GLN D OE1 1 
ATOM 7739 N NE2 . GLN D 1 147 ? 87.692  148.621 111.203 1.00 98.57  ? 221 GLN D NE2 1 
ATOM 7740 N N   . SER D 1 148 ? 91.130  151.689 115.488 1.00 96.81  ? 222 SER D N   1 
ATOM 7741 C CA  . SER D 1 148 ? 91.474  152.489 116.658 1.00 98.35  ? 222 SER D CA  1 
ATOM 7742 C C   . SER D 1 148 ? 92.983  152.601 116.825 1.00 98.49  ? 222 SER D C   1 
ATOM 7743 O O   . SER D 1 148 ? 93.504  153.680 117.130 1.00 98.75  ? 222 SER D O   1 
ATOM 7744 C CB  . SER D 1 148 ? 90.838  151.886 117.910 1.00 97.07  ? 222 SER D CB  1 
ATOM 7745 O OG  . SER D 1 148 ? 91.164  152.643 119.063 1.00 96.47  ? 222 SER D OG  1 
ATOM 7746 N N   . GLN D 1 149 ? 93.702  151.495 116.624 1.00 91.16  ? 223 GLN D N   1 
ATOM 7747 C CA  . GLN D 1 149 ? 95.154  151.517 116.760 1.00 89.40  ? 223 GLN D CA  1 
ATOM 7748 C C   . GLN D 1 149 ? 95.793  152.417 115.710 1.00 90.97  ? 223 GLN D C   1 
ATOM 7749 O O   . GLN D 1 149 ? 96.721  153.178 116.014 1.00 92.16  ? 223 GLN D O   1 
ATOM 7750 C CB  . GLN D 1 149 ? 95.702  150.096 116.661 1.00 86.43  ? 223 GLN D CB  1 
ATOM 7751 C CG  . GLN D 1 149 ? 95.079  149.132 117.653 1.00 83.93  ? 223 GLN D CG  1 
ATOM 7752 C CD  . GLN D 1 149 ? 95.597  147.721 117.493 1.00 89.29  ? 223 GLN D CD  1 
ATOM 7753 O OE1 . GLN D 1 149 ? 96.485  147.463 116.681 1.00 93.10  ? 223 GLN D OE1 1 
ATOM 7754 N NE2 . GLN D 1 149 ? 95.041  146.795 118.264 1.00 90.24  ? 223 GLN D NE2 1 
ATOM 7755 N N   . VAL D 1 150 ? 95.310  152.348 114.468 1.00 84.87  ? 224 VAL D N   1 
ATOM 7756 C CA  . VAL D 1 150 ? 95.860  153.191 113.410 1.00 85.97  ? 224 VAL D CA  1 
ATOM 7757 C C   . VAL D 1 150 ? 95.583  154.659 113.700 1.00 82.57  ? 224 VAL D C   1 
ATOM 7758 O O   . VAL D 1 150 ? 96.455  155.517 113.514 1.00 85.10  ? 224 VAL D O   1 
ATOM 7759 C CB  . VAL D 1 150 ? 95.305  152.764 112.039 1.00 90.29  ? 224 VAL D CB  1 
ATOM 7760 C CG1 . VAL D 1 150 ? 95.720  153.756 110.967 1.00 89.98  ? 224 VAL D CG1 1 
ATOM 7761 C CG2 . VAL D 1 150 ? 95.803  151.374 111.680 1.00 91.27  ? 224 VAL D CG2 1 
ATOM 7762 N N   . THR D 1 151 ? 94.371  154.975 114.161 1.00 85.48  ? 225 THR D N   1 
ATOM 7763 C CA  . THR D 1 151 ? 94.055  156.359 114.498 1.00 90.45  ? 225 THR D CA  1 
ATOM 7764 C C   . THR D 1 151 ? 94.923  156.859 115.646 1.00 92.98  ? 225 THR D C   1 
ATOM 7765 O O   . THR D 1 151 ? 95.374  158.010 115.636 1.00 93.73  ? 225 THR D O   1 
ATOM 7766 C CB  . THR D 1 151 ? 92.574  156.501 114.846 1.00 93.77  ? 225 THR D CB  1 
ATOM 7767 O OG1 . THR D 1 151 ? 92.229  155.567 115.877 1.00 91.78  ? 225 THR D OG1 1 
ATOM 7768 C CG2 . THR D 1 151 ? 91.708  156.255 113.618 1.00 94.41  ? 225 THR D CG2 1 
ATOM 7769 N N   . GLN D 1 152 ? 95.161  156.010 116.648 1.00 98.08  ? 226 GLN D N   1 
ATOM 7770 C CA  . GLN D 1 152 ? 96.024  156.404 117.757 1.00 96.97  ? 226 GLN D CA  1 
ATOM 7771 C C   . GLN D 1 152 ? 97.455  156.642 117.287 1.00 98.18  ? 226 GLN D C   1 
ATOM 7772 O O   . GLN D 1 152 ? 98.109  157.590 117.735 1.00 99.77  ? 226 GLN D O   1 
ATOM 7773 C CB  . GLN D 1 152 ? 95.989  155.341 118.854 1.00 94.02  ? 226 GLN D CB  1 
ATOM 7774 C CG  . GLN D 1 152 ? 96.703  155.750 120.131 1.00 96.62  ? 226 GLN D CG  1 
ATOM 7775 C CD  . GLN D 1 152 ? 96.633  154.685 121.207 1.00 99.68  ? 226 GLN D CD  1 
ATOM 7776 O OE1 . GLN D 1 152 ? 96.135  153.583 120.975 1.00 99.14  ? 226 GLN D OE1 1 
ATOM 7777 N NE2 . GLN D 1 152 ? 97.133  155.009 122.394 1.00 99.81  ? 226 GLN D NE2 1 
ATOM 7778 N N   . VAL D 1 153 ? 97.960  155.789 116.394 1.00 83.85  ? 227 VAL D N   1 
ATOM 7779 C CA  . VAL D 1 153 ? 99.319  155.968 115.891 1.00 77.43  ? 227 VAL D CA  1 
ATOM 7780 C C   . VAL D 1 153 ? 99.428  157.253 115.079 1.00 78.44  ? 227 VAL D C   1 
ATOM 7781 O O   . VAL D 1 153 ? 100.391 158.016 115.224 1.00 75.67  ? 227 VAL D O   1 
ATOM 7782 C CB  . VAL D 1 153 ? 99.750  154.740 115.073 1.00 76.18  ? 227 VAL D CB  1 
ATOM 7783 C CG1 . VAL D 1 153 ? 100.942 155.079 114.197 1.00 78.05  ? 227 VAL D CG1 1 
ATOM 7784 C CG2 . VAL D 1 153 ? 100.077 153.583 115.999 1.00 81.91  ? 227 VAL D CG2 1 
ATOM 7785 N N   . ILE D 1 154 ? 98.448  157.515 114.213 1.00 95.90  ? 228 ILE D N   1 
ATOM 7786 C CA  . ILE D 1 154 ? 98.487  158.717 113.385 1.00 94.29  ? 228 ILE D CA  1 
ATOM 7787 C C   . ILE D 1 154 ? 98.340  159.968 114.243 1.00 93.63  ? 228 ILE D C   1 
ATOM 7788 O O   . ILE D 1 154 ? 99.116  160.922 114.114 1.00 95.88  ? 228 ILE D O   1 
ATOM 7789 C CB  . ILE D 1 154 ? 97.402  158.652 112.295 1.00 93.18  ? 228 ILE D CB  1 
ATOM 7790 C CG1 . ILE D 1 154 ? 97.662  157.481 111.347 1.00 91.14  ? 228 ILE D CG1 1 
ATOM 7791 C CG2 . ILE D 1 154 ? 97.322  159.967 111.537 1.00 94.55  ? 228 ILE D CG2 1 
ATOM 7792 C CD1 . ILE D 1 154 ? 96.571  157.276 110.326 1.00 92.11  ? 228 ILE D CD1 1 
ATOM 7793 N N   . GLU D 1 155 ? 97.350  159.982 115.135 1.00 100.80 ? 229 GLU D N   1 
ATOM 7794 C CA  . GLU D 1 155 ? 97.062  161.192 115.898 1.00 102.90 ? 229 GLU D CA  1 
ATOM 7795 C C   . GLU D 1 155 ? 97.904  161.266 117.166 1.00 105.83 ? 229 GLU D C   1 
ATOM 7796 O O   . GLU D 1 155 ? 98.669  162.216 117.363 1.00 106.61 ? 229 GLU D O   1 
ATOM 7797 C CB  . GLU D 1 155 ? 95.570  161.255 116.234 1.00 103.41 ? 229 GLU D CB  1 
ATOM 7798 C CG  . GLU D 1 155 ? 94.664  161.340 115.015 1.00 105.74 ? 229 GLU D CG  1 
ATOM 7799 C CD  . GLU D 1 155 ? 93.195  161.409 115.382 1.00 106.81 ? 229 GLU D CD  1 
ATOM 7800 O OE1 . GLU D 1 155 ? 92.875  161.294 116.584 1.00 105.75 ? 229 GLU D OE1 1 
ATOM 7801 O OE2 . GLU D 1 155 ? 92.360  161.577 114.469 1.00 107.00 ? 229 GLU D OE2 1 
ATOM 7802 N N   . GLY D 1 156 ? 97.780  160.268 118.037 1.00 109.30 ? 230 GLY D N   1 
ATOM 7803 C CA  . GLY D 1 156 ? 98.488  160.269 119.297 1.00 108.23 ? 230 GLY D CA  1 
ATOM 7804 C C   . GLY D 1 156 ? 99.934  159.836 119.157 1.00 108.98 ? 230 GLY D C   1 
ATOM 7805 O O   . GLY D 1 156 ? 100.438 159.553 118.070 1.00 110.00 ? 230 GLY D O   1 
ATOM 7806 N N   . ASN D 1 157 ? 100.612 159.788 120.299 1.00 113.08 ? 231 ASN D N   1 
ATOM 7807 C CA  . ASN D 1 157 ? 102.013 159.399 120.374 1.00 115.36 ? 231 ASN D CA  1 
ATOM 7808 C C   . ASN D 1 157 ? 102.118 157.994 120.951 1.00 113.43 ? 231 ASN D C   1 
ATOM 7809 O O   . ASN D 1 157 ? 101.513 157.697 121.986 1.00 111.75 ? 231 ASN D O   1 
ATOM 7810 C CB  . ASN D 1 157 ? 102.809 160.384 121.233 1.00 115.44 ? 231 ASN D CB  1 
ATOM 7811 C CG  . ASN D 1 157 ? 102.772 161.796 120.686 1.00 116.60 ? 231 ASN D CG  1 
ATOM 7812 O OD1 . ASN D 1 157 ? 101.889 162.148 119.904 1.00 116.98 ? 231 ASN D OD1 1 
ATOM 7813 N ND2 . ASN D 1 157 ? 103.732 162.616 121.097 1.00 115.84 ? 231 ASN D ND2 1 
ATOM 7814 N N   . ALA D 1 158 ? 102.884 157.139 120.282 1.00 104.51 ? 232 ALA D N   1 
ATOM 7815 C CA  . ALA D 1 158 ? 103.129 155.777 120.730 1.00 104.35 ? 232 ALA D CA  1 
ATOM 7816 C C   . ALA D 1 158 ? 104.630 155.527 120.817 1.00 106.57 ? 232 ALA D C   1 
ATOM 7817 O O   . ALA D 1 158 ? 105.422 156.092 120.061 1.00 107.91 ? 232 ALA D O   1 
ATOM 7818 C CB  . ALA D 1 158 ? 102.466 154.760 119.794 1.00 101.83 ? 232 ALA D CB  1 
ATOM 7819 N N   . ALA D 1 159 ? 105.014 154.663 121.752 1.00 98.88  ? 233 ALA D N   1 
ATOM 7820 C CA  . ALA D 1 159 ? 106.416 154.389 122.025 1.00 93.06  ? 233 ALA D CA  1 
ATOM 7821 C C   . ALA D 1 159 ? 107.063 153.649 120.861 1.00 95.44  ? 233 ALA D C   1 
ATOM 7822 O O   . ALA D 1 159 ? 106.417 152.867 120.159 1.00 97.83  ? 233 ALA D O   1 
ATOM 7823 C CB  . ALA D 1 159 ? 106.565 153.570 123.308 1.00 90.96  ? 233 ALA D CB  1 
ATOM 7824 N N   . VAL D 1 160 ? 108.358 153.906 120.662 1.00 81.21  ? 234 VAL D N   1 
ATOM 7825 C CA  . VAL D 1 160 ? 109.112 153.321 119.563 1.00 81.83  ? 234 VAL D CA  1 
ATOM 7826 C C   . VAL D 1 160 ? 110.423 152.749 120.086 1.00 80.53  ? 234 VAL D C   1 
ATOM 7827 O O   . VAL D 1 160 ? 110.922 153.134 121.145 1.00 78.97  ? 234 VAL D O   1 
ATOM 7828 C CB  . VAL D 1 160 ? 109.391 154.342 118.439 1.00 78.51  ? 234 VAL D CB  1 
ATOM 7829 C CG1 . VAL D 1 160 ? 108.098 154.744 117.751 1.00 80.75  ? 234 VAL D CG1 1 
ATOM 7830 C CG2 . VAL D 1 160 ? 110.102 155.560 118.998 1.00 76.24  ? 234 VAL D CG2 1 
ATOM 7831 N N   . VAL D 1 161 ? 110.975 151.811 119.320 1.00 75.89  ? 235 VAL D N   1 
ATOM 7832 C CA  . VAL D 1 161 ? 112.302 151.253 119.557 1.00 72.83  ? 235 VAL D CA  1 
ATOM 7833 C C   . VAL D 1 161 ? 113.165 151.591 118.352 1.00 72.56  ? 235 VAL D C   1 
ATOM 7834 O O   . VAL D 1 161 ? 112.835 151.213 117.221 1.00 74.03  ? 235 VAL D O   1 
ATOM 7835 C CB  . VAL D 1 161 ? 112.258 149.734 119.782 1.00 70.85  ? 235 VAL D CB  1 
ATOM 7836 C CG1 . VAL D 1 161 ? 113.663 149.155 119.740 1.00 70.00  ? 235 VAL D CG1 1 
ATOM 7837 C CG2 . VAL D 1 161 ? 111.602 149.413 121.103 1.00 71.16  ? 235 VAL D CG2 1 
ATOM 7838 N N   . LEU D 1 162 ? 114.269 152.296 118.589 1.00 59.00  ? 236 LEU D N   1 
ATOM 7839 C CA  . LEU D 1 162 ? 115.192 152.665 117.517 1.00 55.75  ? 236 LEU D CA  1 
ATOM 7840 C C   . LEU D 1 162 ? 116.141 151.496 117.293 1.00 58.37  ? 236 LEU D C   1 
ATOM 7841 O O   . LEU D 1 162 ? 117.245 151.446 117.837 1.00 60.96  ? 236 LEU D O   1 
ATOM 7842 C CB  . LEU D 1 162 ? 115.939 153.947 117.859 1.00 59.44  ? 236 LEU D CB  1 
ATOM 7843 C CG  . LEU D 1 162 ? 115.087 155.212 117.939 1.00 60.51  ? 236 LEU D CG  1 
ATOM 7844 C CD1 . LEU D 1 162 ? 115.948 156.411 118.292 1.00 58.08  ? 236 LEU D CD1 1 
ATOM 7845 C CD2 . LEU D 1 162 ? 114.354 155.441 116.630 1.00 59.47  ? 236 LEU D CD2 1 
ATOM 7846 N N   . ARG D 1 163 ? 115.700 150.544 116.477 1.00 58.81  ? 237 ARG D N   1 
ATOM 7847 C CA  . ARG D 1 163 ? 116.486 149.347 116.216 1.00 62.64  ? 237 ARG D CA  1 
ATOM 7848 C C   . ARG D 1 163 ? 117.709 149.683 115.374 1.00 63.94  ? 237 ARG D C   1 
ATOM 7849 O O   . ARG D 1 163 ? 117.626 150.465 114.423 1.00 67.56  ? 237 ARG D O   1 
ATOM 7850 C CB  . ARG D 1 163 ? 115.625 148.303 115.512 1.00 65.33  ? 237 ARG D CB  1 
ATOM 7851 C CG  . ARG D 1 163 ? 114.207 148.217 116.045 1.00 66.40  ? 237 ARG D CG  1 
ATOM 7852 C CD  . ARG D 1 163 ? 113.469 147.026 115.467 1.00 64.48  ? 237 ARG D CD  1 
ATOM 7853 N NE  . ARG D 1 163 ? 113.522 145.871 116.353 1.00 62.96  ? 237 ARG D NE  1 
ATOM 7854 C CZ  . ARG D 1 163 ? 112.636 145.619 117.306 1.00 62.84  ? 237 ARG D CZ  1 
ATOM 7855 N NH1 . ARG D 1 163 ? 111.612 146.426 117.528 1.00 67.64  ? 237 ARG D NH1 1 
ATOM 7856 N NH2 . ARG D 1 163 ? 112.781 144.531 118.055 1.00 65.28  ? 237 ARG D NH2 1 
ATOM 7857 N N   . SER D 1 164 ? 118.843 149.081 115.718 1.00 50.97  ? 238 SER D N   1 
ATOM 7858 C CA  . SER D 1 164 ? 120.092 149.378 115.036 1.00 49.02  ? 238 SER D CA  1 
ATOM 7859 C C   . SER D 1 164 ? 120.216 148.576 113.747 1.00 55.37  ? 238 SER D C   1 
ATOM 7860 O O   . SER D 1 164 ? 119.600 147.520 113.583 1.00 65.42  ? 238 SER D O   1 
ATOM 7861 C CB  . SER D 1 164 ? 121.281 149.080 115.948 1.00 56.78  ? 238 SER D CB  1 
ATOM 7862 O OG  . SER D 1 164 ? 121.193 149.816 117.155 1.00 60.81  ? 238 SER D OG  1 
ATOM 7863 N N   . ARG D 1 165 ? 121.027 149.093 112.827 1.00 49.25  ? 239 ARG D N   1 
ATOM 7864 C CA  . ARG D 1 165 ? 121.323 148.429 111.567 1.00 40.96  ? 239 ARG D CA  1 
ATOM 7865 C C   . ARG D 1 165 ? 122.820 148.500 111.297 1.00 48.04  ? 239 ARG D C   1 
ATOM 7866 O O   . ARG D 1 165 ? 123.558 149.245 111.946 1.00 55.08  ? 239 ARG D O   1 
ATOM 7867 C CB  . ARG D 1 165 ? 120.532 149.043 110.405 1.00 43.58  ? 239 ARG D CB  1 
ATOM 7868 C CG  . ARG D 1 165 ? 119.034 148.840 110.513 1.00 52.40  ? 239 ARG D CG  1 
ATOM 7869 C CD  . ARG D 1 165 ? 118.341 149.092 109.191 1.00 48.10  ? 239 ARG D CD  1 
ATOM 7870 N NE  . ARG D 1 165 ? 118.453 150.482 108.773 1.00 44.68  ? 239 ARG D NE  1 
ATOM 7871 C CZ  . ARG D 1 165 ? 117.945 150.967 107.650 1.00 55.25  ? 239 ARG D CZ  1 
ATOM 7872 N NH1 . ARG D 1 165 ? 117.287 150.196 106.800 1.00 59.08  ? 239 ARG D NH1 1 
ATOM 7873 N NH2 . ARG D 1 165 ? 118.101 152.258 107.371 1.00 57.81  ? 239 ARG D NH2 1 
ATOM 7874 N N   . LEU D 1 166 ? 123.267 147.707 110.326 1.00 54.99  ? 240 LEU D N   1 
ATOM 7875 C CA  . LEU D 1 166 ? 124.682 147.545 110.019 1.00 56.08  ? 240 LEU D CA  1 
ATOM 7876 C C   . LEU D 1 166 ? 124.978 148.034 108.609 1.00 56.18  ? 240 LEU D C   1 
ATOM 7877 O O   . LEU D 1 166 ? 124.270 147.677 107.662 1.00 57.28  ? 240 LEU D O   1 
ATOM 7878 C CB  . LEU D 1 166 ? 125.101 146.081 110.159 1.00 48.78  ? 240 LEU D CB  1 
ATOM 7879 C CG  . LEU D 1 166 ? 125.130 145.514 111.575 1.00 50.26  ? 240 LEU D CG  1 
ATOM 7880 C CD1 . LEU D 1 166 ? 125.438 144.033 111.547 1.00 53.67  ? 240 LEU D CD1 1 
ATOM 7881 C CD2 . LEU D 1 166 ? 126.137 146.257 112.434 1.00 52.62  ? 240 LEU D CD2 1 
ATOM 7882 N N   . LYS D 1 167 ? 126.030 148.838 108.472 1.00 52.96  ? 241 LYS D N   1 
ATOM 7883 C CA  . LYS D 1 167 ? 126.496 149.304 107.167 1.00 45.50  ? 241 LYS D CA  1 
ATOM 7884 C C   . LYS D 1 167 ? 127.617 148.384 106.709 1.00 50.59  ? 241 LYS D C   1 
ATOM 7885 O O   . LYS D 1 167 ? 128.794 148.619 106.983 1.00 60.13  ? 241 LYS D O   1 
ATOM 7886 C CB  . LYS D 1 167 ? 126.967 150.751 107.240 1.00 48.25  ? 241 LYS D CB  1 
ATOM 7887 C CG  . LYS D 1 167 ? 125.861 151.769 107.430 1.00 53.63  ? 241 LYS D CG  1 
ATOM 7888 C CD  . LYS D 1 167 ? 126.430 153.175 107.530 1.00 55.38  ? 241 LYS D CD  1 
ATOM 7889 C CE  . LYS D 1 167 ? 125.330 154.211 107.693 1.00 61.10  ? 241 LYS D CE  1 
ATOM 7890 N NZ  . LYS D 1 167 ? 124.431 154.254 106.506 1.00 60.41  ? 241 LYS D NZ  1 
ATOM 7891 N N   . VAL D 1 168 ? 127.255 147.323 106.000 1.00 43.97  ? 242 VAL D N   1 
ATOM 7892 C CA  . VAL D 1 168 ? 128.235 146.381 105.477 1.00 47.98  ? 242 VAL D CA  1 
ATOM 7893 C C   . VAL D 1 168 ? 128.678 146.840 104.096 1.00 54.61  ? 242 VAL D C   1 
ATOM 7894 O O   . VAL D 1 168 ? 127.853 147.231 103.260 1.00 55.27  ? 242 VAL D O   1 
ATOM 7895 C CB  . VAL D 1 168 ? 127.671 144.951 105.444 1.00 48.21  ? 242 VAL D CB  1 
ATOM 7896 C CG1 . VAL D 1 168 ? 127.382 144.473 106.856 1.00 51.11  ? 242 VAL D CG1 1 
ATOM 7897 C CG2 . VAL D 1 168 ? 126.408 144.893 104.619 1.00 55.19  ? 242 VAL D CG2 1 
ATOM 7898 N N   . ARG D 1 169 ? 129.987 146.824 103.866 1.00 55.50  ? 243 ARG D N   1 
ATOM 7899 C CA  . ARG D 1 169 ? 130.581 147.255 102.608 1.00 46.69  ? 243 ARG D CA  1 
ATOM 7900 C C   . ARG D 1 169 ? 131.502 146.156 102.102 1.00 51.45  ? 243 ARG D C   1 
ATOM 7901 O O   . ARG D 1 169 ? 132.469 145.792 102.779 1.00 59.90  ? 243 ARG D O   1 
ATOM 7902 C CB  . ARG D 1 169 ? 131.347 148.566 102.789 1.00 55.45  ? 243 ARG D CB  1 
ATOM 7903 C CG  . ARG D 1 169 ? 132.144 148.995 101.573 1.00 60.16  ? 243 ARG D CG  1 
ATOM 7904 C CD  . ARG D 1 169 ? 132.594 150.441 101.694 1.00 57.16  ? 243 ARG D CD  1 
ATOM 7905 N NE  . ARG D 1 169 ? 133.162 150.732 103.005 1.00 61.30  ? 243 ARG D NE  1 
ATOM 7906 C CZ  . ARG D 1 169 ? 134.448 150.621 103.306 1.00 62.10  ? 243 ARG D CZ  1 
ATOM 7907 N NH1 . ARG D 1 169 ? 135.336 150.228 102.408 1.00 59.92  ? 243 ARG D NH1 1 
ATOM 7908 N NH2 . ARG D 1 169 ? 134.854 150.913 104.538 1.00 61.85  ? 243 ARG D NH2 1 
ATOM 7909 N N   . VAL D 1 170 ? 131.205 145.635 100.916 1.00 46.41  ? 244 VAL D N   1 
ATOM 7910 C CA  . VAL D 1 170 ? 131.984 144.564 100.306 1.00 39.74  ? 244 VAL D CA  1 
ATOM 7911 C C   . VAL D 1 170 ? 132.879 145.180 99.242  1.00 47.17  ? 244 VAL D C   1 
ATOM 7912 O O   . VAL D 1 170 ? 132.391 145.824 98.305  1.00 57.61  ? 244 VAL D O   1 
ATOM 7913 C CB  . VAL D 1 170 ? 131.078 143.480 99.705  1.00 43.43  ? 244 VAL D CB  1 
ATOM 7914 C CG1 . VAL D 1 170 ? 131.914 142.364 99.111  1.00 48.93  ? 244 VAL D CG1 1 
ATOM 7915 C CG2 . VAL D 1 170 ? 130.132 142.937 100.760 1.00 49.94  ? 244 VAL D CG2 1 
ATOM 7916 N N   . VAL D 1 171 ? 134.186 144.985 99.383  1.00 56.99  ? 245 VAL D N   1 
ATOM 7917 C CA  . VAL D 1 171 ? 135.178 145.569 98.490  1.00 61.18  ? 245 VAL D CA  1 
ATOM 7918 C C   . VAL D 1 171 ? 135.765 144.457 97.635  1.00 65.90  ? 245 VAL D C   1 
ATOM 7919 O O   . VAL D 1 171 ? 136.207 143.428 98.160  1.00 65.18  ? 245 VAL D O   1 
ATOM 7920 C CB  . VAL D 1 171 ? 136.279 146.304 99.272  1.00 59.16  ? 245 VAL D CB  1 
ATOM 7921 C CG1 . VAL D 1 171 ? 137.263 146.954 98.315  1.00 59.85  ? 245 VAL D CG1 1 
ATOM 7922 C CG2 . VAL D 1 171 ? 135.664 147.340 100.196 1.00 56.64  ? 245 VAL D CG2 1 
ATOM 7923 N N   . LYS D 1 172 ? 135.769 144.666 96.324  1.00 64.18  ? 246 LYS D N   1 
ATOM 7924 C CA  . LYS D 1 172 ? 136.263 143.689 95.369  1.00 52.64  ? 246 LYS D CA  1 
ATOM 7925 C C   . LYS D 1 172 ? 137.632 144.107 94.849  1.00 57.75  ? 246 LYS D C   1 
ATOM 7926 O O   . LYS D 1 172 ? 137.925 145.297 94.705  1.00 62.02  ? 246 LYS D O   1 
ATOM 7927 C CB  . LYS D 1 172 ? 135.288 143.535 94.203  1.00 53.13  ? 246 LYS D CB  1 
ATOM 7928 C CG  . LYS D 1 172 ? 133.998 142.835 94.571  1.00 57.18  ? 246 LYS D CG  1 
ATOM 7929 C CD  . LYS D 1 172 ? 134.232 141.373 94.868  1.00 54.13  ? 246 LYS D CD  1 
ATOM 7930 C CE  . LYS D 1 172 ? 132.920 140.653 95.106  1.00 57.12  ? 246 LYS D CE  1 
ATOM 7931 N NZ  . LYS D 1 172 ? 133.125 139.203 95.364  1.00 62.06  ? 246 LYS D NZ  1 
ATOM 7932 N N   . GLU D 1 173 ? 138.470 143.114 94.570  1.00 84.17  ? 247 GLU D N   1 
ATOM 7933 C CA  . GLU D 1 173 ? 139.819 143.368 94.075  1.00 91.44  ? 247 GLU D CA  1 
ATOM 7934 C C   . GLU D 1 173 ? 139.788 143.951 92.665  1.00 93.47  ? 247 GLU D C   1 
ATOM 7935 O O   . GLU D 1 173 ? 140.596 144.815 92.324  1.00 93.35  ? 247 GLU D O   1 
ATOM 7936 C CB  . GLU D 1 173 ? 140.651 142.081 94.105  1.00 90.80  ? 247 GLU D CB  1 
ATOM 7937 C CG  . GLU D 1 173 ? 140.104 140.946 93.247  1.00 94.42  ? 247 GLU D CG  1 
ATOM 7938 C CD  . GLU D 1 173 ? 140.587 141.005 91.810  1.00 104.19 ? 247 GLU D CD  1 
ATOM 7939 O OE1 . GLU D 1 173 ? 141.611 141.671 91.552  1.00 103.09 ? 247 GLU D OE1 1 
ATOM 7940 O OE2 . GLU D 1 173 ? 139.940 140.387 90.938  1.00 107.53 ? 247 GLU D OE2 1 
ATOM 7941 N N   . ALA D 1 203 ? 132.359 149.341 97.322  1.00 84.17  ? 277 ALA D N   1 
ATOM 7942 C CA  . ALA D 1 203 ? 131.801 149.341 95.975  1.00 86.92  ? 277 ALA D CA  1 
ATOM 7943 C C   . ALA D 1 203 ? 130.309 149.027 96.001  1.00 85.62  ? 277 ALA D C   1 
ATOM 7944 O O   . ALA D 1 203 ? 129.561 149.455 95.122  1.00 83.58  ? 277 ALA D O   1 
ATOM 7945 C CB  . ALA D 1 203 ? 132.538 148.341 95.095  1.00 81.46  ? 277 ALA D CB  1 
ATOM 7946 N N   . MET D 1 204 ? 129.879 148.280 97.016  1.00 70.00  ? 278 MET D N   1 
ATOM 7947 C CA  . MET D 1 204 ? 128.477 147.888 97.161  1.00 65.80  ? 278 MET D CA  1 
ATOM 7948 C C   . MET D 1 204 ? 128.138 147.864 98.648  1.00 71.84  ? 278 MET D C   1 
ATOM 7949 O O   . MET D 1 204 ? 128.507 146.925 99.358  1.00 74.58  ? 278 MET D O   1 
ATOM 7950 C CB  . MET D 1 204 ? 128.215 146.535 96.511  1.00 65.20  ? 278 MET D CB  1 
ATOM 7951 C CG  . MET D 1 204 ? 127.938 146.608 95.020  1.00 70.11  ? 278 MET D CG  1 
ATOM 7952 S SD  . MET D 1 204 ? 126.545 147.682 94.626  1.00 82.73  ? 278 MET D SD  1 
ATOM 7953 C CE  . MET D 1 204 ? 125.232 146.883 95.545  1.00 70.02  ? 278 MET D CE  1 
ATOM 7954 N N   . GLN D 1 205 ? 127.437 148.895 99.111  1.00 60.25  ? 279 GLN D N   1 
ATOM 7955 C CA  . GLN D 1 205 ? 126.997 148.952 100.496 1.00 49.34  ? 279 GLN D CA  1 
ATOM 7956 C C   . GLN D 1 205 ? 125.646 148.271 100.653 1.00 53.60  ? 279 GLN D C   1 
ATOM 7957 O O   . GLN D 1 205 ? 124.867 148.172 99.701  1.00 58.92  ? 279 GLN D O   1 
ATOM 7958 C CB  . GLN D 1 205 ? 126.897 150.399 100.973 1.00 48.01  ? 279 GLN D CB  1 
ATOM 7959 C CG  . GLN D 1 205 ? 128.197 151.170 100.927 1.00 52.19  ? 279 GLN D CG  1 
ATOM 7960 C CD  . GLN D 1 205 ? 128.078 152.532 101.576 1.00 57.83  ? 279 GLN D CD  1 
ATOM 7961 O OE1 . GLN D 1 205 ? 127.055 152.857 102.177 1.00 59.84  ? 279 GLN D OE1 1 
ATOM 7962 N NE2 . GLN D 1 205 ? 129.125 153.340 101.456 1.00 56.70  ? 279 GLN D NE2 1 
ATOM 7963 N N   . TYR D 1 206 ? 125.373 147.798 101.864 1.00 51.92  ? 280 TYR D N   1 
ATOM 7964 C CA  . TYR D 1 206 ? 124.069 147.271 102.227 1.00 47.45  ? 280 TYR D CA  1 
ATOM 7965 C C   . TYR D 1 206 ? 123.722 147.724 103.636 1.00 57.49  ? 280 TYR D C   1 
ATOM 7966 O O   . TYR D 1 206 ? 124.606 148.014 104.447 1.00 65.69  ? 280 TYR D O   1 
ATOM 7967 C CB  . TYR D 1 206 ? 124.026 145.742 102.165 1.00 46.07  ? 280 TYR D CB  1 
ATOM 7968 C CG  . TYR D 1 206 ? 124.492 145.137 100.865 1.00 50.46  ? 280 TYR D CG  1 
ATOM 7969 C CD1 . TYR D 1 206 ? 123.624 144.990 99.794  1.00 56.51  ? 280 TYR D CD1 1 
ATOM 7970 C CD2 . TYR D 1 206 ? 125.796 144.691 100.715 1.00 54.81  ? 280 TYR D CD2 1 
ATOM 7971 C CE1 . TYR D 1 206 ? 124.044 144.426 98.605  1.00 55.61  ? 280 TYR D CE1 1 
ATOM 7972 C CE2 . TYR D 1 206 ? 126.227 144.126 99.531  1.00 59.16  ? 280 TYR D CE2 1 
ATOM 7973 C CZ  . TYR D 1 206 ? 125.347 143.996 98.480  1.00 58.82  ? 280 TYR D CZ  1 
ATOM 7974 O OH  . TYR D 1 206 ? 125.773 143.434 97.299  1.00 57.32  ? 280 TYR D OH  1 
ATOM 7975 N N   . GLN D 1 207 ? 122.427 147.786 103.919 1.00 50.86  ? 281 GLN D N   1 
ATOM 7976 C CA  . GLN D 1 207 ? 121.927 148.026 105.265 1.00 46.25  ? 281 GLN D CA  1 
ATOM 7977 C C   . GLN D 1 207 ? 121.252 146.750 105.750 1.00 44.45  ? 281 GLN D C   1 
ATOM 7978 O O   . GLN D 1 207 ? 120.324 146.252 105.105 1.00 55.00  ? 281 GLN D O   1 
ATOM 7979 C CB  . GLN D 1 207 ? 120.951 149.201 105.290 1.00 48.38  ? 281 GLN D CB  1 
ATOM 7980 C CG  . GLN D 1 207 ? 121.531 150.511 104.782 1.00 49.63  ? 281 GLN D CG  1 
ATOM 7981 C CD  . GLN D 1 207 ? 122.631 151.058 105.666 1.00 58.58  ? 281 GLN D CD  1 
ATOM 7982 O OE1 . GLN D 1 207 ? 123.509 151.783 105.201 1.00 58.33  ? 281 GLN D OE1 1 
ATOM 7983 N NE2 . GLN D 1 207 ? 122.580 150.728 106.951 1.00 57.99  ? 281 GLN D NE2 1 
ATOM 7984 N N   . VAL D 1 208 ? 121.719 146.225 106.876 1.00 45.52  ? 282 VAL D N   1 
ATOM 7985 C CA  . VAL D 1 208 ? 121.276 144.938 107.394 1.00 45.30  ? 282 VAL D CA  1 
ATOM 7986 C C   . VAL D 1 208 ? 120.634 145.153 108.754 1.00 50.35  ? 282 VAL D C   1 
ATOM 7987 O O   . VAL D 1 208 ? 121.233 145.776 109.638 1.00 59.89  ? 282 VAL D O   1 
ATOM 7988 C CB  . VAL D 1 208 ? 122.445 143.943 107.493 1.00 53.35  ? 282 VAL D CB  1 
ATOM 7989 C CG1 . VAL D 1 208 ? 121.990 142.673 108.162 1.00 54.50  ? 282 VAL D CG1 1 
ATOM 7990 C CG2 . VAL D 1 208 ? 123.003 143.649 106.110 1.00 57.21  ? 282 VAL D CG2 1 
ATOM 7991 N N   . LEU D 1 209 ? 119.420 144.631 108.922 1.00 50.31  ? 283 LEU D N   1 
ATOM 7992 C CA  . LEU D 1 209 ? 118.681 144.779 110.169 1.00 48.07  ? 283 LEU D CA  1 
ATOM 7993 C C   . LEU D 1 209 ? 118.909 143.608 111.116 1.00 45.81  ? 283 LEU D C   1 
ATOM 7994 O O   . LEU D 1 209 ? 119.141 143.812 112.311 1.00 54.63  ? 283 LEU D O   1 
ATOM 7995 C CB  . LEU D 1 209 ? 117.186 144.933 109.880 1.00 52.25  ? 283 LEU D CB  1 
ATOM 7996 C CG  . LEU D 1 209 ? 116.289 145.099 111.105 1.00 48.33  ? 283 LEU D CG  1 
ATOM 7997 C CD1 . LEU D 1 209 ? 116.686 146.332 111.891 1.00 49.19  ? 283 LEU D CD1 1 
ATOM 7998 C CD2 . LEU D 1 209 ? 114.833 145.173 110.688 1.00 55.10  ? 283 LEU D CD2 1 
ATOM 7999 N N   . ASN D 1 210 ? 118.844 142.379 110.607 1.00 51.05  ? 284 ASN D N   1 
ATOM 8000 C CA  . ASN D 1 210 ? 118.994 141.211 111.468 1.00 59.51  ? 284 ASN D CA  1 
ATOM 8001 C C   . ASN D 1 210 ? 120.441 140.733 111.551 1.00 59.93  ? 284 ASN D C   1 
ATOM 8002 O O   . ASN D 1 210 ? 121.034 140.727 112.633 1.00 54.95  ? 284 ASN D O   1 
ATOM 8003 C CB  . ASN D 1 210 ? 118.090 140.069 110.988 1.00 53.42  ? 284 ASN D CB  1 
ATOM 8004 C CG  . ASN D 1 210 ? 116.640 140.276 111.363 1.00 60.32  ? 284 ASN D CG  1 
ATOM 8005 O OD1 . ASN D 1 210 ? 115.736 139.871 110.635 1.00 64.16  ? 284 ASN D OD1 1 
ATOM 8006 N ND2 . ASN D 1 210 ? 116.409 140.909 112.507 1.00 63.71  ? 284 ASN D ND2 1 
ATOM 8007 N N   . GLU D 1 211 ? 121.025 140.343 110.420 1.00 43.80  ? 285 GLU D N   1 
ATOM 8008 C CA  . GLU D 1 211 ? 122.279 139.609 110.472 1.00 38.48  ? 285 GLU D CA  1 
ATOM 8009 C C   . GLU D 1 211 ? 122.929 139.565 109.099 1.00 43.14  ? 285 GLU D C   1 
ATOM 8010 O O   . GLU D 1 211 ? 122.246 139.524 108.073 1.00 47.93  ? 285 GLU D O   1 
ATOM 8011 C CB  . GLU D 1 211 ? 122.044 138.183 110.972 1.00 46.57  ? 285 GLU D CB  1 
ATOM 8012 C CG  . GLU D 1 211 ? 120.979 137.457 110.175 1.00 54.75  ? 285 GLU D CG  1 
ATOM 8013 C CD  . GLU D 1 211 ? 120.473 136.209 110.858 1.00 56.63  ? 285 GLU D CD  1 
ATOM 8014 O OE1 . GLU D 1 211 ? 120.832 135.978 112.032 1.00 62.63  ? 285 GLU D OE1 1 
ATOM 8015 O OE2 . GLU D 1 211 ? 119.709 135.460 110.216 1.00 58.51  ? 285 GLU D OE2 1 
ATOM 8016 N N   . VAL D 1 212 ? 124.260 139.559 109.097 1.00 37.90  ? 286 VAL D N   1 
ATOM 8017 C CA  . VAL D 1 212 ? 125.057 139.217 107.926 1.00 26.07  ? 286 VAL D CA  1 
ATOM 8018 C C   . VAL D 1 212 ? 125.798 137.921 108.233 1.00 39.81  ? 286 VAL D C   1 
ATOM 8019 O O   . VAL D 1 212 ? 126.425 137.790 109.290 1.00 47.32  ? 286 VAL D O   1 
ATOM 8020 C CB  . VAL D 1 212 ? 126.021 140.353 107.531 1.00 25.77  ? 286 VAL D CB  1 
ATOM 8021 C CG1 . VAL D 1 212 ? 127.030 140.633 108.628 1.00 35.38  ? 286 VAL D CG1 1 
ATOM 8022 C CG2 . VAL D 1 212 ? 126.734 140.013 106.236 1.00 37.87  ? 286 VAL D CG2 1 
ATOM 8023 N N   . VAL D 1 213 ? 125.689 136.950 107.331 1.00 35.66  ? 287 VAL D N   1 
ATOM 8024 C CA  . VAL D 1 213 ? 126.216 135.608 107.546 1.00 25.05  ? 287 VAL D CA  1 
ATOM 8025 C C   . VAL D 1 213 ? 127.281 135.325 106.499 1.00 39.39  ? 287 VAL D C   1 
ATOM 8026 O O   . VAL D 1 213 ? 127.052 135.529 105.302 1.00 42.95  ? 287 VAL D O   1 
ATOM 8027 C CB  . VAL D 1 213 ? 125.106 134.544 107.492 1.00 31.25  ? 287 VAL D CB  1 
ATOM 8028 C CG1 . VAL D 1 213 ? 125.662 133.183 107.862 1.00 41.19  ? 287 VAL D CG1 1 
ATOM 8029 C CG2 . VAL D 1 213 ? 123.972 134.919 108.421 1.00 33.67  ? 287 VAL D CG2 1 
ATOM 8030 N N   . ILE D 1 214 ? 128.439 134.854 106.951 1.00 46.33  ? 288 ILE D N   1 
ATOM 8031 C CA  . ILE D 1 214 ? 129.524 134.426 106.078 1.00 37.95  ? 288 ILE D CA  1 
ATOM 8032 C C   . ILE D 1 214 ? 129.734 132.942 106.331 1.00 39.97  ? 288 ILE D C   1 
ATOM 8033 O O   . ILE D 1 214 ? 130.324 132.559 107.348 1.00 51.93  ? 288 ILE D O   1 
ATOM 8034 C CB  . ILE D 1 214 ? 130.814 135.217 106.327 1.00 39.53  ? 288 ILE D CB  1 
ATOM 8035 C CG1 . ILE D 1 214 ? 130.614 136.702 106.024 1.00 49.55  ? 288 ILE D CG1 1 
ATOM 8036 C CG2 . ILE D 1 214 ? 131.942 134.663 105.480 1.00 44.76  ? 288 ILE D CG2 1 
ATOM 8037 C CD1 . ILE D 1 214 ? 130.161 137.524 107.210 1.00 51.65  ? 288 ILE D CD1 1 
ATOM 8038 N N   . ASP D 1 215 ? 129.273 132.100 105.409 1.00 47.62  ? 289 ASP D N   1 
ATOM 8039 C CA  . ASP D 1 215 ? 129.280 130.663 105.630 1.00 44.32  ? 289 ASP D CA  1 
ATOM 8040 C C   . ASP D 1 215 ? 129.691 129.939 104.358 1.00 54.92  ? 289 ASP D C   1 
ATOM 8041 O O   . ASP D 1 215 ? 129.752 130.520 103.271 1.00 61.97  ? 289 ASP D O   1 
ATOM 8042 C CB  . ASP D 1 215 ? 127.910 130.163 106.098 1.00 43.95  ? 289 ASP D CB  1 
ATOM 8043 C CG  . ASP D 1 215 ? 126.820 130.410 105.076 1.00 61.70  ? 289 ASP D CG  1 
ATOM 8044 O OD1 . ASP D 1 215 ? 126.918 131.401 104.321 1.00 66.51  ? 289 ASP D OD1 1 
ATOM 8045 O OD2 . ASP D 1 215 ? 125.862 129.609 105.026 1.00 64.71  ? 289 ASP D OD2 1 
ATOM 8046 N N   . ARG D 1 216 ? 129.976 128.648 104.512 1.00 75.80  ? 290 ARG D N   1 
ATOM 8047 C CA  . ARG D 1 216 ? 130.288 127.774 103.386 1.00 74.51  ? 290 ARG D CA  1 
ATOM 8048 C C   . ARG D 1 216 ? 129.008 127.526 102.594 1.00 73.50  ? 290 ARG D C   1 
ATOM 8049 O O   . ARG D 1 216 ? 128.072 126.883 103.080 1.00 80.97  ? 290 ARG D O   1 
ATOM 8050 C CB  . ARG D 1 216 ? 130.932 126.480 103.884 1.00 74.85  ? 290 ARG D CB  1 
ATOM 8051 C CG  . ARG D 1 216 ? 130.075 125.631 104.817 1.00 76.77  ? 290 ARG D CG  1 
ATOM 8052 C CD  . ARG D 1 216 ? 130.818 124.400 105.305 1.00 79.06  ? 290 ARG D CD  1 
ATOM 8053 N NE  . ARG D 1 216 ? 129.994 123.584 106.188 1.00 85.24  ? 290 ARG D NE  1 
ATOM 8054 C CZ  . ARG D 1 216 ? 130.387 122.446 106.744 1.00 82.69  ? 290 ARG D CZ  1 
ATOM 8055 N NH1 . ARG D 1 216 ? 131.595 121.953 106.527 1.00 78.44  ? 290 ARG D NH1 1 
ATOM 8056 N NH2 . ARG D 1 216 ? 129.547 121.786 107.536 1.00 80.61  ? 290 ARG D NH2 1 
ATOM 8057 N N   . GLY D 1 217 ? 128.952 128.067 101.383 1.00 68.10  ? 291 GLY D N   1 
ATOM 8058 C CA  . GLY D 1 217 ? 127.737 128.055 100.606 1.00 74.49  ? 291 GLY D CA  1 
ATOM 8059 C C   . GLY D 1 217 ? 127.576 126.801 99.777  1.00 76.63  ? 291 GLY D C   1 
ATOM 8060 O O   . GLY D 1 217 ? 127.687 125.676 100.277 1.00 72.18  ? 291 GLY D O   1 
ATOM 8061 N N   . PRO D 1 218 ? 127.311 126.973 98.482  1.00 71.65  ? 292 PRO D N   1 
ATOM 8062 C CA  . PRO D 1 218 ? 127.155 125.810 97.601  1.00 68.86  ? 292 PRO D CA  1 
ATOM 8063 C C   . PRO D 1 218 ? 128.469 125.076 97.407  1.00 66.84  ? 292 PRO D C   1 
ATOM 8064 O O   . PRO D 1 218 ? 129.011 125.022 96.299  1.00 69.00  ? 292 PRO D O   1 
ATOM 8065 C CB  . PRO D 1 218 ? 126.654 126.426 96.287  1.00 64.83  ? 292 PRO D CB  1 
ATOM 8066 C CG  . PRO D 1 218 ? 126.116 127.774 96.670  1.00 63.56  ? 292 PRO D CG  1 
ATOM 8067 C CD  . PRO D 1 218 ? 126.981 128.232 97.798  1.00 62.68  ? 292 PRO D CD  1 
ATOM 8068 N N   . SER D 1 219 ? 128.981 124.508 98.488  1.00 69.35  ? 293 SER D N   1 
ATOM 8069 C CA  . SER D 1 219 ? 130.265 123.817 98.509  1.00 74.29  ? 293 SER D CA  1 
ATOM 8070 C C   . SER D 1 219 ? 130.314 123.000 99.794  1.00 77.27  ? 293 SER D C   1 
ATOM 8071 O O   . SER D 1 219 ? 129.307 122.865 100.499 1.00 79.30  ? 293 SER D O   1 
ATOM 8072 C CB  . SER D 1 219 ? 131.431 124.803 98.404  1.00 75.22  ? 293 SER D CB  1 
ATOM 8073 O OG  . SER D 1 219 ? 132.673 124.123 98.379  1.00 70.55  ? 293 SER D OG  1 
ATOM 8074 N N   . SER D 1 220 ? 131.486 122.458 100.104 1.00 84.61  ? 294 SER D N   1 
ATOM 8075 C CA  . SER D 1 220 ? 131.664 121.606 101.270 1.00 86.13  ? 294 SER D CA  1 
ATOM 8076 C C   . SER D 1 220 ? 132.982 121.982 101.935 1.00 84.76  ? 294 SER D C   1 
ATOM 8077 O O   . SER D 1 220 ? 133.547 123.048 101.670 1.00 86.96  ? 294 SER D O   1 
ATOM 8078 C CB  . SER D 1 220 ? 131.606 120.125 100.873 1.00 86.30  ? 294 SER D CB  1 
ATOM 8079 O OG  . SER D 1 220 ? 130.344 119.797 100.317 1.00 87.65  ? 294 SER D OG  1 
ATOM 8080 N N   . TYR D 1 221 ? 133.448 121.107 102.832 1.00 81.00  ? 295 TYR D N   1 
ATOM 8081 C CA  . TYR D 1 221 ? 134.706 121.266 103.558 1.00 85.43  ? 295 TYR D CA  1 
ATOM 8082 C C   . TYR D 1 221 ? 134.609 122.415 104.558 1.00 85.14  ? 295 TYR D C   1 
ATOM 8083 O O   . TYR D 1 221 ? 133.727 123.273 104.448 1.00 81.65  ? 295 TYR D O   1 
ATOM 8084 C CB  . TYR D 1 221 ? 135.871 121.462 102.575 1.00 85.99  ? 295 TYR D CB  1 
ATOM 8085 C CG  . TYR D 1 221 ? 137.191 121.859 103.201 1.00 89.38  ? 295 TYR D CG  1 
ATOM 8086 C CD1 . TYR D 1 221 ? 137.901 120.969 103.997 1.00 90.77  ? 295 TYR D CD1 1 
ATOM 8087 C CD2 . TYR D 1 221 ? 137.729 123.121 102.989 1.00 90.02  ? 295 TYR D CD2 1 
ATOM 8088 C CE1 . TYR D 1 221 ? 139.108 121.328 104.569 1.00 92.98  ? 295 TYR D CE1 1 
ATOM 8089 C CE2 . TYR D 1 221 ? 138.935 123.489 103.556 1.00 91.96  ? 295 TYR D CE2 1 
ATOM 8090 C CZ  . TYR D 1 221 ? 139.620 122.589 104.345 1.00 92.43  ? 295 TYR D CZ  1 
ATOM 8091 O OH  . TYR D 1 221 ? 140.821 122.953 104.910 1.00 91.27  ? 295 TYR D OH  1 
ATOM 8092 N N   . LEU D 1 222 ? 135.503 122.435 105.543 1.00 80.24  ? 296 LEU D N   1 
ATOM 8093 C CA  . LEU D 1 222 ? 135.458 123.431 106.602 1.00 82.10  ? 296 LEU D CA  1 
ATOM 8094 C C   . LEU D 1 222 ? 135.784 124.815 106.038 1.00 83.58  ? 296 LEU D C   1 
ATOM 8095 O O   . LEU D 1 222 ? 136.103 124.981 104.857 1.00 87.05  ? 296 LEU D O   1 
ATOM 8096 C CB  . LEU D 1 222 ? 136.423 123.043 107.719 1.00 80.82  ? 296 LEU D CB  1 
ATOM 8097 C CG  . LEU D 1 222 ? 136.042 123.431 109.146 1.00 81.24  ? 296 LEU D CG  1 
ATOM 8098 C CD1 . LEU D 1 222 ? 134.681 122.856 109.499 1.00 81.47  ? 296 LEU D CD1 1 
ATOM 8099 C CD2 . LEU D 1 222 ? 137.099 122.952 110.126 1.00 80.19  ? 296 LEU D CD2 1 
ATOM 8100 N N   . SER D 1 223 ? 135.705 125.828 106.897 1.00 81.57  ? 297 SER D N   1 
ATOM 8101 C CA  . SER D 1 223 ? 135.965 127.203 106.498 1.00 81.78  ? 297 SER D CA  1 
ATOM 8102 C C   . SER D 1 223 ? 137.075 127.790 107.357 1.00 84.63  ? 297 SER D C   1 
ATOM 8103 O O   . SER D 1 223 ? 137.223 127.445 108.532 1.00 81.51  ? 297 SER D O   1 
ATOM 8104 C CB  . SER D 1 223 ? 134.706 128.073 106.614 1.00 81.02  ? 297 SER D CB  1 
ATOM 8105 O OG  . SER D 1 223 ? 133.674 127.591 105.773 1.00 79.92  ? 297 SER D OG  1 
ATOM 8106 N N   . ASN D 1 224 ? 137.862 128.683 106.751 1.00 77.64  ? 298 ASN D N   1 
ATOM 8107 C CA  . ASN D 1 224 ? 138.940 129.392 107.446 1.00 71.23  ? 298 ASN D CA  1 
ATOM 8108 C C   . ASN D 1 224 ? 138.885 130.851 107.000 1.00 72.81  ? 298 ASN D C   1 
ATOM 8109 O O   . ASN D 1 224 ? 139.460 131.220 105.973 1.00 74.78  ? 298 ASN D O   1 
ATOM 8110 C CB  . ASN D 1 224 ? 140.297 128.765 107.161 1.00 67.69  ? 298 ASN D CB  1 
ATOM 8111 C CG  . ASN D 1 224 ? 140.374 127.320 107.601 1.00 73.71  ? 298 ASN D CG  1 
ATOM 8112 O OD1 . ASN D 1 224 ? 140.778 127.022 108.725 1.00 73.23  ? 298 ASN D OD1 1 
ATOM 8113 N ND2 . ASN D 1 224 ? 139.987 126.410 106.715 1.00 74.78  ? 298 ASN D ND2 1 
ATOM 8114 N N   . VAL D 1 225 ? 138.193 131.677 107.780 1.00 62.68  ? 299 VAL D N   1 
ATOM 8115 C CA  . VAL D 1 225 ? 138.025 133.092 107.479 1.00 58.97  ? 299 VAL D CA  1 
ATOM 8116 C C   . VAL D 1 225 ? 138.468 133.902 108.690 1.00 59.94  ? 299 VAL D C   1 
ATOM 8117 O O   . VAL D 1 225 ? 138.205 133.523 109.836 1.00 57.69  ? 299 VAL D O   1 
ATOM 8118 C CB  . VAL D 1 225 ? 136.568 133.417 107.077 1.00 56.91  ? 299 VAL D CB  1 
ATOM 8119 C CG1 . VAL D 1 225 ? 135.613 133.167 108.222 1.00 62.31  ? 299 VAL D CG1 1 
ATOM 8120 C CG2 . VAL D 1 225 ? 136.453 134.842 106.581 1.00 57.77  ? 299 VAL D CG2 1 
ATOM 8121 N N   . ASP D 1 226 ? 139.173 135.001 108.434 1.00 65.48  ? 300 ASP D N   1 
ATOM 8122 C CA  . ASP D 1 226 ? 139.731 135.832 109.491 1.00 61.77  ? 300 ASP D CA  1 
ATOM 8123 C C   . ASP D 1 226 ? 138.793 136.983 109.823 1.00 63.68  ? 300 ASP D C   1 
ATOM 8124 O O   . ASP D 1 226 ? 138.144 137.549 108.938 1.00 71.47  ? 300 ASP D O   1 
ATOM 8125 C CB  . ASP D 1 226 ? 141.097 136.382 109.081 1.00 68.45  ? 300 ASP D CB  1 
ATOM 8126 C CG  . ASP D 1 226 ? 142.157 135.302 108.989 1.00 74.34  ? 300 ASP D CG  1 
ATOM 8127 O OD1 . ASP D 1 226 ? 141.854 134.142 109.335 1.00 72.79  ? 300 ASP D OD1 1 
ATOM 8128 O OD2 . ASP D 1 226 ? 143.292 135.615 108.575 1.00 74.40  ? 300 ASP D OD2 1 
ATOM 8129 N N   . VAL D 1 227 ? 138.729 137.326 111.106 1.00 55.35  ? 301 VAL D N   1 
ATOM 8130 C CA  . VAL D 1 227 ? 137.892 138.411 111.600 1.00 51.95  ? 301 VAL D CA  1 
ATOM 8131 C C   . VAL D 1 227 ? 138.804 139.464 112.210 1.00 55.57  ? 301 VAL D C   1 
ATOM 8132 O O   . VAL D 1 227 ? 139.505 139.191 113.192 1.00 67.16  ? 301 VAL D O   1 
ATOM 8133 C CB  . VAL D 1 227 ? 136.866 137.918 112.631 1.00 51.29  ? 301 VAL D CB  1 
ATOM 8134 C CG1 . VAL D 1 227 ? 136.072 139.083 113.183 1.00 51.12  ? 301 VAL D CG1 1 
ATOM 8135 C CG2 . VAL D 1 227 ? 135.944 136.885 112.010 1.00 56.80  ? 301 VAL D CG2 1 
ATOM 8136 N N   . TYR D 1 228 ? 138.794 140.661 111.635 1.00 56.90  ? 302 TYR D N   1 
ATOM 8137 C CA  . TYR D 1 228 ? 139.577 141.779 112.137 1.00 56.32  ? 302 TYR D CA  1 
ATOM 8138 C C   . TYR D 1 228 ? 138.653 142.809 112.767 1.00 59.38  ? 302 TYR D C   1 
ATOM 8139 O O   . TYR D 1 228 ? 137.630 143.181 112.185 1.00 63.40  ? 302 TYR D O   1 
ATOM 8140 C CB  . TYR D 1 228 ? 140.403 142.428 111.023 1.00 59.67  ? 302 TYR D CB  1 
ATOM 8141 C CG  . TYR D 1 228 ? 141.470 141.527 110.448 1.00 62.58  ? 302 TYR D CG  1 
ATOM 8142 C CD1 . TYR D 1 228 ? 141.184 140.656 109.408 1.00 61.76  ? 302 TYR D CD1 1 
ATOM 8143 C CD2 . TYR D 1 228 ? 142.762 141.545 110.949 1.00 67.13  ? 302 TYR D CD2 1 
ATOM 8144 C CE1 . TYR D 1 228 ? 142.156 139.831 108.881 1.00 58.07  ? 302 TYR D CE1 1 
ATOM 8145 C CE2 . TYR D 1 228 ? 143.741 140.723 110.429 1.00 66.88  ? 302 TYR D CE2 1 
ATOM 8146 C CZ  . TYR D 1 228 ? 143.432 139.868 109.396 1.00 61.62  ? 302 TYR D CZ  1 
ATOM 8147 O OH  . TYR D 1 228 ? 144.404 139.047 108.874 1.00 64.38  ? 302 TYR D OH  1 
ATOM 8148 N N   . LEU D 1 229 ? 139.020 143.265 113.961 1.00 56.00  ? 303 LEU D N   1 
ATOM 8149 C CA  . LEU D 1 229 ? 138.229 144.224 114.722 1.00 56.64  ? 303 LEU D CA  1 
ATOM 8150 C C   . LEU D 1 229 ? 139.135 145.393 115.085 1.00 57.88  ? 303 LEU D C   1 
ATOM 8151 O O   . LEU D 1 229 ? 140.059 145.238 115.889 1.00 59.81  ? 303 LEU D O   1 
ATOM 8152 C CB  . LEU D 1 229 ? 137.633 143.564 115.967 1.00 56.91  ? 303 LEU D CB  1 
ATOM 8153 C CG  . LEU D 1 229 ? 136.619 144.308 116.833 1.00 56.31  ? 303 LEU D CG  1 
ATOM 8154 C CD1 . LEU D 1 229 ? 135.699 143.323 117.521 1.00 58.97  ? 303 LEU D CD1 1 
ATOM 8155 C CD2 . LEU D 1 229 ? 137.332 145.132 117.868 1.00 52.77  ? 303 LEU D CD2 1 
ATOM 8156 N N   . ASP D 1 230 ? 138.866 146.556 114.491 1.00 65.48  ? 304 ASP D N   1 
ATOM 8157 C CA  . ASP D 1 230 ? 139.692 147.752 114.672 1.00 64.49  ? 304 ASP D CA  1 
ATOM 8158 C C   . ASP D 1 230 ? 141.147 147.490 114.293 1.00 64.94  ? 304 ASP D C   1 
ATOM 8159 O O   . ASP D 1 230 ? 142.075 147.948 114.962 1.00 66.47  ? 304 ASP D O   1 
ATOM 8160 C CB  . ASP D 1 230 ? 139.587 148.289 116.100 1.00 65.71  ? 304 ASP D CB  1 
ATOM 8161 C CG  . ASP D 1 230 ? 138.300 149.051 116.340 1.00 69.79  ? 304 ASP D CG  1 
ATOM 8162 O OD1 . ASP D 1 230 ? 137.431 149.044 115.444 1.00 71.92  ? 304 ASP D OD1 1 
ATOM 8163 O OD2 . ASP D 1 230 ? 138.158 149.656 117.423 1.00 68.22  ? 304 ASP D OD2 1 
ATOM 8164 N N   . GLY D 1 231 ? 141.349 146.745 113.209 1.00 70.89  ? 305 GLY D N   1 
ATOM 8165 C CA  . GLY D 1 231 ? 142.672 146.502 112.679 1.00 71.89  ? 305 GLY D CA  1 
ATOM 8166 C C   . GLY D 1 231 ? 143.444 145.378 113.333 1.00 71.58  ? 305 GLY D C   1 
ATOM 8167 O O   . GLY D 1 231 ? 144.568 145.093 112.902 1.00 77.55  ? 305 GLY D O   1 
ATOM 8168 N N   . HIS D 1 232 ? 142.888 144.728 114.349 1.00 68.61  ? 306 HIS D N   1 
ATOM 8169 C CA  . HIS D 1 232 ? 143.563 143.649 115.055 1.00 72.64  ? 306 HIS D CA  1 
ATOM 8170 C C   . HIS D 1 232 ? 142.822 142.342 114.819 1.00 73.11  ? 306 HIS D C   1 
ATOM 8171 O O   . HIS D 1 232 ? 141.596 142.286 114.951 1.00 79.13  ? 306 HIS D O   1 
ATOM 8172 C CB  . HIS D 1 232 ? 143.649 143.945 116.553 1.00 73.77  ? 306 HIS D CB  1 
ATOM 8173 C CG  . HIS D 1 232 ? 144.359 145.222 116.875 1.00 75.89  ? 306 HIS D CG  1 
ATOM 8174 N ND1 . HIS D 1 232 ? 144.243 145.852 118.095 1.00 76.45  ? 306 HIS D ND1 1 
ATOM 8175 C CD2 . HIS D 1 232 ? 145.202 145.983 116.138 1.00 75.07  ? 306 HIS D CD2 1 
ATOM 8176 C CE1 . HIS D 1 232 ? 144.979 146.949 118.094 1.00 76.74  ? 306 HIS D CE1 1 
ATOM 8177 N NE2 . HIS D 1 232 ? 145.572 147.051 116.919 1.00 79.08  ? 306 HIS D NE2 1 
ATOM 8178 N N   . LEU D 1 233 ? 143.569 141.296 114.475 1.00 55.35  ? 307 LEU D N   1 
ATOM 8179 C CA  . LEU D 1 233 ? 142.978 139.983 114.249 1.00 57.02  ? 307 LEU D CA  1 
ATOM 8180 C C   . LEU D 1 233 ? 142.541 139.399 115.584 1.00 62.55  ? 307 LEU D C   1 
ATOM 8181 O O   . LEU D 1 233 ? 143.359 138.850 116.329 1.00 68.87  ? 307 LEU D O   1 
ATOM 8182 C CB  . LEU D 1 233 ? 143.979 139.068 113.553 1.00 59.91  ? 307 LEU D CB  1 
ATOM 8183 C CG  . LEU D 1 233 ? 143.564 137.613 113.337 1.00 65.45  ? 307 LEU D CG  1 
ATOM 8184 C CD1 . LEU D 1 233 ? 142.333 137.531 112.448 1.00 64.48  ? 307 LEU D CD1 1 
ATOM 8185 C CD2 . LEU D 1 233 ? 144.711 136.814 112.741 1.00 63.53  ? 307 LEU D CD2 1 
ATOM 8186 N N   . ILE D 1 234 ? 141.253 139.525 115.898 1.00 57.79  ? 308 ILE D N   1 
ATOM 8187 C CA  . ILE D 1 234 ? 140.754 139.023 117.172 1.00 65.47  ? 308 ILE D CA  1 
ATOM 8188 C C   . ILE D 1 234 ? 140.705 137.501 117.171 1.00 69.08  ? 308 ILE D C   1 
ATOM 8189 O O   . ILE D 1 234 ? 141.112 136.853 118.141 1.00 76.56  ? 308 ILE D O   1 
ATOM 8190 C CB  . ILE D 1 234 ? 139.379 139.635 117.494 1.00 65.64  ? 308 ILE D CB  1 
ATOM 8191 C CG1 . ILE D 1 234 ? 138.441 139.531 116.292 1.00 64.45  ? 308 ILE D CG1 1 
ATOM 8192 C CG2 . ILE D 1 234 ? 139.535 141.085 117.913 1.00 65.58  ? 308 ILE D CG2 1 
ATOM 8193 C CD1 . ILE D 1 234 ? 137.054 140.060 116.561 1.00 65.38  ? 308 ILE D CD1 1 
ATOM 8194 N N   . THR D 1 235 ? 140.212 136.907 116.087 1.00 56.68  ? 309 THR D N   1 
ATOM 8195 C CA  . THR D 1 235 ? 140.039 135.463 116.039 1.00 64.16  ? 309 THR D CA  1 
ATOM 8196 C C   . THR D 1 235 ? 139.957 135.010 114.591 1.00 66.96  ? 309 THR D C   1 
ATOM 8197 O O   . THR D 1 235 ? 139.655 135.794 113.689 1.00 73.42  ? 309 THR D O   1 
ATOM 8198 C CB  . THR D 1 235 ? 138.786 135.021 116.805 1.00 69.42  ? 309 THR D CB  1 
ATOM 8199 O OG1 . THR D 1 235 ? 138.745 133.590 116.873 1.00 73.35  ? 309 THR D OG1 1 
ATOM 8200 C CG2 . THR D 1 235 ? 137.529 135.528 116.114 1.00 68.33  ? 309 THR D CG2 1 
ATOM 8201 N N   . THR D 1 236 ? 140.244 133.728 114.387 1.00 66.53  ? 310 THR D N   1 
ATOM 8202 C CA  . THR D 1 236 ? 140.043 133.051 113.111 1.00 68.16  ? 310 THR D CA  1 
ATOM 8203 C C   . THR D 1 236 ? 139.037 131.934 113.347 1.00 69.89  ? 310 THR D C   1 
ATOM 8204 O O   . THR D 1 236 ? 139.348 130.944 114.018 1.00 66.51  ? 310 THR D O   1 
ATOM 8205 C CB  . THR D 1 236 ? 141.356 132.502 112.559 1.00 70.00  ? 310 THR D CB  1 
ATOM 8206 O OG1 . THR D 1 236 ? 142.245 133.587 112.264 1.00 73.27  ? 310 THR D OG1 1 
ATOM 8207 C CG2 . THR D 1 236 ? 141.105 131.694 111.294 1.00 70.05  ? 310 THR D CG2 1 
ATOM 8208 N N   . VAL D 1 237 ? 137.840 132.089 112.799 1.00 74.82  ? 311 VAL D N   1 
ATOM 8209 C CA  . VAL D 1 237 ? 136.751 131.155 113.053 1.00 73.54  ? 311 VAL D CA  1 
ATOM 8210 C C   . VAL D 1 237 ? 136.818 130.016 112.044 1.00 72.67  ? 311 VAL D C   1 
ATOM 8211 O O   . VAL D 1 237 ? 137.011 130.238 110.842 1.00 74.48  ? 311 VAL D O   1 
ATOM 8212 C CB  . VAL D 1 237 ? 135.388 131.871 113.019 1.00 74.91  ? 311 VAL D CB  1 
ATOM 8213 C CG1 . VAL D 1 237 ? 135.399 133.057 113.967 1.00 71.70  ? 311 VAL D CG1 1 
ATOM 8214 C CG2 . VAL D 1 237 ? 135.041 132.340 111.622 1.00 72.79  ? 311 VAL D CG2 1 
ATOM 8215 N N   . GLN D 1 238 ? 136.710 128.789 112.544 1.00 69.76  ? 312 GLN D N   1 
ATOM 8216 C CA  . GLN D 1 238 ? 136.676 127.593 111.717 1.00 69.87  ? 312 GLN D CA  1 
ATOM 8217 C C   . GLN D 1 238 ? 135.421 126.806 112.054 1.00 70.44  ? 312 GLN D C   1 
ATOM 8218 O O   . GLN D 1 238 ? 135.134 126.559 113.230 1.00 73.13  ? 312 GLN D O   1 
ATOM 8219 C CB  . GLN D 1 238 ? 137.924 126.733 111.927 1.00 72.49  ? 312 GLN D CB  1 
ATOM 8220 C CG  . GLN D 1 238 ? 139.224 127.454 111.628 1.00 73.88  ? 312 GLN D CG  1 
ATOM 8221 C CD  . GLN D 1 238 ? 140.439 126.578 111.844 1.00 77.48  ? 312 GLN D CD  1 
ATOM 8222 O OE1 . GLN D 1 238 ? 140.318 125.373 112.062 1.00 77.19  ? 312 GLN D OE1 1 
ATOM 8223 N NE2 . GLN D 1 238 ? 141.621 127.179 111.782 1.00 74.74  ? 312 GLN D NE2 1 
ATOM 8224 N N   . GLY D 1 239 ? 134.690 126.418 111.034 1.00 60.22  ? 313 GLY D N   1 
ATOM 8225 C CA  . GLY D 1 239 ? 133.398 125.796 111.195 1.00 60.76  ? 313 GLY D CA  1 
ATOM 8226 C C   . GLY D 1 239 ? 132.520 126.142 110.007 1.00 61.47  ? 313 GLY D C   1 
ATOM 8227 O O   . GLY D 1 239 ? 133.008 126.298 108.890 1.00 65.37  ? 313 GLY D O   1 
ATOM 8228 N N   . ASP D 1 240 ? 131.220 126.254 110.269 1.00 53.88  ? 314 ASP D N   1 
ATOM 8229 C CA  . ASP D 1 240 ? 130.301 126.593 109.191 1.00 57.04  ? 314 ASP D CA  1 
ATOM 8230 C C   . ASP D 1 240 ? 130.349 128.077 108.842 1.00 56.06  ? 314 ASP D C   1 
ATOM 8231 O O   . ASP D 1 240 ? 130.286 128.432 107.660 1.00 65.34  ? 314 ASP D O   1 
ATOM 8232 C CB  . ASP D 1 240 ? 128.883 126.167 109.556 1.00 60.09  ? 314 ASP D CB  1 
ATOM 8233 C CG  . ASP D 1 240 ? 128.746 124.667 109.695 1.00 64.62  ? 314 ASP D CG  1 
ATOM 8234 O OD1 . ASP D 1 240 ? 129.746 123.956 109.465 1.00 65.27  ? 314 ASP D OD1 1 
ATOM 8235 O OD2 . ASP D 1 240 ? 127.640 124.196 110.032 1.00 64.07  ? 314 ASP D OD2 1 
ATOM 8236 N N   . GLY D 1 241 ? 130.465 128.957 109.831 1.00 40.30  ? 315 GLY D N   1 
ATOM 8237 C CA  . GLY D 1 241 ? 130.544 130.375 109.527 1.00 42.93  ? 315 GLY D CA  1 
ATOM 8238 C C   . GLY D 1 241 ? 130.314 131.233 110.762 1.00 39.56  ? 315 GLY D C   1 
ATOM 8239 O O   . GLY D 1 241 ? 130.480 130.778 111.890 1.00 38.30  ? 315 GLY D O   1 
ATOM 8240 N N   . VAL D 1 242 ? 129.935 132.488 110.506 1.00 34.85  ? 316 VAL D N   1 
ATOM 8241 C CA  . VAL D 1 242 ? 129.751 133.501 111.539 1.00 30.79  ? 316 VAL D CA  1 
ATOM 8242 C C   . VAL D 1 242 ? 128.500 134.316 111.222 1.00 40.96  ? 316 VAL D C   1 
ATOM 8243 O O   . VAL D 1 242 ? 128.168 134.549 110.056 1.00 44.80  ? 316 VAL D O   1 
ATOM 8244 C CB  . VAL D 1 242 ? 131.004 134.402 111.660 1.00 29.50  ? 316 VAL D CB  1 
ATOM 8245 C CG1 . VAL D 1 242 ? 131.288 135.109 110.346 1.00 36.67  ? 316 VAL D CG1 1 
ATOM 8246 C CG2 . VAL D 1 242 ? 130.853 135.401 112.796 1.00 43.18  ? 316 VAL D CG2 1 
ATOM 8247 N N   . ILE D 1 243 ? 127.796 134.746 112.274 1.00 37.99  ? 317 ILE D N   1 
ATOM 8248 C CA  . ILE D 1 243 ? 126.475 135.366 112.156 1.00 27.92  ? 317 ILE D CA  1 
ATOM 8249 C C   . ILE D 1 243 ? 126.496 136.770 112.756 1.00 32.30  ? 317 ILE D C   1 
ATOM 8250 O O   . ILE D 1 243 ? 125.609 137.128 113.538 1.00 51.36  ? 317 ILE D O   1 
ATOM 8251 C CB  . ILE D 1 243 ? 125.373 134.511 112.813 1.00 33.74  ? 317 ILE D CB  1 
ATOM 8252 C CG1 . ILE D 1 243 ? 125.348 133.111 112.237 1.00 40.43  ? 317 ILE D CG1 1 
ATOM 8253 C CG2 . ILE D 1 243 ? 123.985 135.035 112.464 1.00 41.15  ? 317 ILE D CG2 1 
ATOM 8254 C CD1 . ILE D 1 243 ? 124.424 132.199 113.002 1.00 42.84  ? 317 ILE D CD1 1 
ATOM 8255 N N   . VAL D 1 244 ? 127.559 137.534 112.500 1.00 21.48  ? 318 VAL D N   1 
ATOM 8256 C CA  . VAL D 1 244 ? 127.638 138.915 112.976 1.00 23.39  ? 318 VAL D CA  1 
ATOM 8257 C C   . VAL D 1 244 ? 126.304 139.618 112.749 1.00 31.24  ? 318 VAL D C   1 
ATOM 8258 O O   . VAL D 1 244 ? 125.802 139.666 111.622 1.00 43.93  ? 318 VAL D O   1 
ATOM 8259 C CB  . VAL D 1 244 ? 128.777 139.678 112.280 1.00 28.31  ? 318 VAL D CB  1 
ATOM 8260 C CG1 . VAL D 1 244 ? 128.691 141.154 112.606 1.00 34.24  ? 318 VAL D CG1 1 
ATOM 8261 C CG2 . VAL D 1 244 ? 130.123 139.112 112.695 1.00 38.91  ? 318 VAL D CG2 1 
ATOM 8262 N N   . SER D 1 245 ? 125.724 140.168 113.816 1.00 37.83  ? 319 SER D N   1 
ATOM 8263 C CA  . SER D 1 245 ? 124.320 140.555 113.793 1.00 27.70  ? 319 SER D CA  1 
ATOM 8264 C C   . SER D 1 245 ? 124.057 141.696 114.765 1.00 39.82  ? 319 SER D C   1 
ATOM 8265 O O   . SER D 1 245 ? 124.852 141.972 115.666 1.00 50.35  ? 319 SER D O   1 
ATOM 8266 C CB  . SER D 1 245 ? 123.419 139.368 114.143 1.00 36.86  ? 319 SER D CB  1 
ATOM 8267 O OG  . SER D 1 245 ? 123.708 138.884 115.441 1.00 34.47  ? 319 SER D OG  1 
ATOM 8268 N N   . THR D 1 246 ? 122.917 142.352 114.564 1.00 48.03  ? 320 THR D N   1 
ATOM 8269 C CA  . THR D 1 246 ? 122.427 143.405 115.439 1.00 41.48  ? 320 THR D CA  1 
ATOM 8270 C C   . THR D 1 246 ? 121.677 142.806 116.626 1.00 50.13  ? 320 THR D C   1 
ATOM 8271 O O   . THR D 1 246 ? 121.350 141.616 116.628 1.00 57.38  ? 320 THR D O   1 
ATOM 8272 C CB  . THR D 1 246 ? 121.502 144.341 114.668 1.00 40.19  ? 320 THR D CB  1 
ATOM 8273 O OG1 . THR D 1 246 ? 120.325 143.627 114.269 1.00 48.91  ? 320 THR D OG1 1 
ATOM 8274 C CG2 . THR D 1 246 ? 122.192 144.881 113.438 1.00 50.64  ? 320 THR D CG2 1 
ATOM 8275 N N   . PRO D 1 247 ? 121.403 143.607 117.662 1.00 45.37  ? 321 PRO D N   1 
ATOM 8276 C CA  . PRO D 1 247 ? 120.573 143.103 118.766 1.00 38.77  ? 321 PRO D CA  1 
ATOM 8277 C C   . PRO D 1 247 ? 119.201 142.628 118.327 1.00 50.67  ? 321 PRO D C   1 
ATOM 8278 O O   . PRO D 1 247 ? 118.641 141.722 118.956 1.00 51.00  ? 321 PRO D O   1 
ATOM 8279 C CB  . PRO D 1 247 ? 120.478 144.311 119.703 1.00 44.57  ? 321 PRO D CB  1 
ATOM 8280 C CG  . PRO D 1 247 ? 121.719 145.059 119.456 1.00 51.83  ? 321 PRO D CG  1 
ATOM 8281 C CD  . PRO D 1 247 ? 122.008 144.909 117.992 1.00 51.67  ? 321 PRO D CD  1 
ATOM 8282 N N   . THR D 1 248 ? 118.632 143.217 117.273 1.00 57.78  ? 322 THR D N   1 
ATOM 8283 C CA  . THR D 1 248 ? 117.345 142.746 116.775 1.00 50.67  ? 322 THR D CA  1 
ATOM 8284 C C   . THR D 1 248 ? 117.449 141.344 116.193 1.00 52.82  ? 322 THR D C   1 
ATOM 8285 O O   . THR D 1 248 ? 116.485 140.574 116.258 1.00 57.12  ? 322 THR D O   1 
ATOM 8286 C CB  . THR D 1 248 ? 116.800 143.709 115.726 1.00 46.33  ? 322 THR D CB  1 
ATOM 8287 O OG1 . THR D 1 248 ? 117.618 143.651 114.552 1.00 56.89  ? 322 THR D OG1 1 
ATOM 8288 C CG2 . THR D 1 248 ? 116.818 145.116 116.268 1.00 52.37  ? 322 THR D CG2 1 
ATOM 8289 N N   . GLY D 1 249 ? 118.599 140.998 115.624 1.00 46.39  ? 323 GLY D N   1 
ATOM 8290 C CA  . GLY D 1 249 ? 118.846 139.666 115.120 1.00 43.53  ? 323 GLY D CA  1 
ATOM 8291 C C   . GLY D 1 249 ? 119.252 138.654 116.161 1.00 51.50  ? 323 GLY D C   1 
ATOM 8292 O O   . GLY D 1 249 ? 119.457 137.484 115.826 1.00 55.42  ? 323 GLY D O   1 
ATOM 8293 N N   . SER D 1 250 ? 119.380 139.071 117.422 1.00 57.67  ? 324 SER D N   1 
ATOM 8294 C CA  . SER D 1 250 ? 119.709 138.150 118.502 1.00 57.60  ? 324 SER D CA  1 
ATOM 8295 C C   . SER D 1 250 ? 118.637 137.094 118.715 1.00 61.20  ? 324 SER D C   1 
ATOM 8296 O O   . SER D 1 250 ? 118.938 136.037 119.278 1.00 64.18  ? 324 SER D O   1 
ATOM 8297 C CB  . SER D 1 250 ? 119.926 138.920 119.804 1.00 59.93  ? 324 SER D CB  1 
ATOM 8298 O OG  . SER D 1 250 ? 118.763 139.641 120.167 1.00 62.59  ? 324 SER D OG  1 
ATOM 8299 N N   . THR D 1 251 ? 117.403 137.359 118.294 1.00 58.26  ? 325 THR D N   1 
ATOM 8300 C CA  . THR D 1 251 ? 116.333 136.375 118.316 1.00 60.19  ? 325 THR D CA  1 
ATOM 8301 C C   . THR D 1 251 ? 116.135 135.708 116.964 1.00 61.28  ? 325 THR D C   1 
ATOM 8302 O O   . THR D 1 251 ? 115.271 134.836 116.834 1.00 64.32  ? 325 THR D O   1 
ATOM 8303 C CB  . THR D 1 251 ? 115.026 137.033 118.767 1.00 65.95  ? 325 THR D CB  1 
ATOM 8304 O OG1 . THR D 1 251 ? 114.691 138.095 117.866 1.00 63.15  ? 325 THR D OG1 1 
ATOM 8305 C CG2 . THR D 1 251 ? 115.180 137.601 120.168 1.00 61.90  ? 325 THR D CG2 1 
ATOM 8306 N N   . ALA D 1 252 ? 116.914 136.096 115.964 1.00 56.67  ? 326 ALA D N   1 
ATOM 8307 C CA  . ALA D 1 252 ? 116.855 135.533 114.624 1.00 56.89  ? 326 ALA D CA  1 
ATOM 8308 C C   . ALA D 1 252 ? 117.792 134.326 114.551 1.00 55.56  ? 326 ALA D C   1 
ATOM 8309 O O   . ALA D 1 252 ? 118.186 133.771 115.580 1.00 57.83  ? 326 ALA D O   1 
ATOM 8310 C CB  . ALA D 1 252 ? 117.190 136.611 113.590 1.00 53.60  ? 326 ALA D CB  1 
ATOM 8311 N N   . TYR D 1 253 ? 118.124 133.890 113.333 1.00 45.79  ? 327 TYR D N   1 
ATOM 8312 C CA  . TYR D 1 253 ? 119.018 132.755 113.114 1.00 44.32  ? 327 TYR D CA  1 
ATOM 8313 C C   . TYR D 1 253 ? 120.275 132.796 113.977 1.00 49.01  ? 327 TYR D C   1 
ATOM 8314 O O   . TYR D 1 253 ? 120.865 131.743 114.241 1.00 57.91  ? 327 TYR D O   1 
ATOM 8315 C CB  . TYR D 1 253 ? 119.391 132.700 111.630 1.00 50.00  ? 327 TYR D CB  1 
ATOM 8316 C CG  . TYR D 1 253 ? 120.409 131.650 111.255 1.00 50.98  ? 327 TYR D CG  1 
ATOM 8317 C CD1 . TYR D 1 253 ? 120.182 130.307 111.520 1.00 54.25  ? 327 TYR D CD1 1 
ATOM 8318 C CD2 . TYR D 1 253 ? 121.582 131.999 110.604 1.00 46.10  ? 327 TYR D CD2 1 
ATOM 8319 C CE1 . TYR D 1 253 ? 121.107 129.347 111.168 1.00 50.07  ? 327 TYR D CE1 1 
ATOM 8320 C CE2 . TYR D 1 253 ? 122.508 131.047 110.247 1.00 46.29  ? 327 TYR D CE2 1 
ATOM 8321 C CZ  . TYR D 1 253 ? 122.267 129.723 110.530 1.00 49.21  ? 327 TYR D CZ  1 
ATOM 8322 O OH  . TYR D 1 253 ? 123.193 128.771 110.174 1.00 56.35  ? 327 TYR D OH  1 
ATOM 8323 N N   . ALA D 1 254 ? 120.699 133.979 114.428 1.00 47.36  ? 328 ALA D N   1 
ATOM 8324 C CA  . ALA D 1 254 ? 121.812 134.053 115.370 1.00 43.81  ? 328 ALA D CA  1 
ATOM 8325 C C   . ALA D 1 254 ? 121.487 133.322 116.666 1.00 37.44  ? 328 ALA D C   1 
ATOM 8326 O O   . ALA D 1 254 ? 122.378 132.756 117.307 1.00 42.00  ? 328 ALA D O   1 
ATOM 8327 C CB  . ALA D 1 254 ? 122.166 135.511 115.653 1.00 41.13  ? 328 ALA D CB  1 
ATOM 8328 N N   . ALA D 1 255 ? 120.214 133.327 117.069 1.00 43.79  ? 329 ALA D N   1 
ATOM 8329 C CA  . ALA D 1 255 ? 119.820 132.628 118.288 1.00 41.30  ? 329 ALA D CA  1 
ATOM 8330 C C   . ALA D 1 255 ? 119.958 131.121 118.144 1.00 45.66  ? 329 ALA D C   1 
ATOM 8331 O O   . ALA D 1 255 ? 120.306 130.435 119.111 1.00 56.16  ? 329 ALA D O   1 
ATOM 8332 C CB  . ALA D 1 255 ? 118.384 132.987 118.666 1.00 45.45  ? 329 ALA D CB  1 
ATOM 8333 N N   . ALA D 1 256 ? 119.688 130.586 116.953 1.00 38.55  ? 330 ALA D N   1 
ATOM 8334 C CA  . ALA D 1 256 ? 119.791 129.148 116.746 1.00 40.60  ? 330 ALA D CA  1 
ATOM 8335 C C   . ALA D 1 256 ? 121.225 128.648 116.844 1.00 49.76  ? 330 ALA D C   1 
ATOM 8336 O O   . ALA D 1 256 ? 121.437 127.441 116.995 1.00 52.66  ? 330 ALA D O   1 
ATOM 8337 C CB  . ALA D 1 256 ? 119.201 128.770 115.389 1.00 37.50  ? 330 ALA D CB  1 
ATOM 8338 N N   . ALA D 1 257 ? 122.208 129.541 116.774 1.00 54.21  ? 331 ALA D N   1 
ATOM 8339 C CA  . ALA D 1 257 ? 123.613 129.167 116.806 1.00 43.85  ? 331 ALA D CA  1 
ATOM 8340 C C   . ALA D 1 257 ? 124.221 129.268 118.197 1.00 44.41  ? 331 ALA D C   1 
ATOM 8341 O O   . ALA D 1 257 ? 125.437 129.109 118.342 1.00 53.17  ? 331 ALA D O   1 
ATOM 8342 C CB  . ALA D 1 257 ? 124.406 130.028 115.826 1.00 43.22  ? 331 ALA D CB  1 
ATOM 8343 N N   . GLY D 1 258 ? 123.412 129.522 119.218 1.00 46.36  ? 332 GLY D N   1 
ATOM 8344 C CA  . GLY D 1 258 ? 123.899 129.606 120.577 1.00 50.97  ? 332 GLY D CA  1 
ATOM 8345 C C   . GLY D 1 258 ? 124.059 131.000 121.138 1.00 48.13  ? 332 GLY D C   1 
ATOM 8346 O O   . GLY D 1 258 ? 124.574 131.140 122.253 1.00 48.87  ? 332 GLY D O   1 
ATOM 8347 N N   . ALA D 1 259 ? 123.637 132.032 120.414 1.00 50.09  ? 333 ALA D N   1 
ATOM 8348 C CA  . ALA D 1 259 ? 123.796 133.393 120.896 1.00 49.13  ? 333 ALA D CA  1 
ATOM 8349 C C   . ALA D 1 259 ? 122.778 133.709 121.986 1.00 49.06  ? 333 ALA D C   1 
ATOM 8350 O O   . ALA D 1 259 ? 121.689 133.134 122.048 1.00 56.12  ? 333 ALA D O   1 
ATOM 8351 C CB  . ALA D 1 259 ? 123.655 134.392 119.748 1.00 51.15  ? 333 ALA D CB  1 
ATOM 8352 N N   . SER D 1 260 ? 123.151 134.642 122.856 1.00 49.85  ? 334 SER D N   1 
ATOM 8353 C CA  . SER D 1 260 ? 122.247 135.131 123.881 1.00 49.25  ? 334 SER D CA  1 
ATOM 8354 C C   . SER D 1 260 ? 121.258 136.125 123.279 1.00 53.21  ? 334 SER D C   1 
ATOM 8355 O O   . SER D 1 260 ? 121.453 136.656 122.183 1.00 59.69  ? 334 SER D O   1 
ATOM 8356 C CB  . SER D 1 260 ? 123.028 135.775 125.023 1.00 52.28  ? 334 SER D CB  1 
ATOM 8357 O OG  . SER D 1 260 ? 123.873 134.831 125.654 1.00 62.31  ? 334 SER D OG  1 
ATOM 8358 N N   . MET D 1 261 ? 120.184 136.379 124.016 1.00 48.69  ? 335 MET D N   1 
ATOM 8359 C CA  . MET D 1 261 ? 119.088 137.215 123.544 1.00 45.86  ? 335 MET D CA  1 
ATOM 8360 C C   . MET D 1 261 ? 119.288 138.631 124.069 1.00 42.82  ? 335 MET D C   1 
ATOM 8361 O O   . MET D 1 261 ? 119.160 138.879 125.272 1.00 58.84  ? 335 MET D O   1 
ATOM 8362 C CB  . MET D 1 261 ? 117.749 136.633 123.985 1.00 53.01  ? 335 MET D CB  1 
ATOM 8363 C CG  . MET D 1 261 ? 117.381 135.359 123.242 1.00 53.40  ? 335 MET D CG  1 
ATOM 8364 S SD  . MET D 1 261 ? 116.085 134.414 124.053 1.00 70.57  ? 335 MET D SD  1 
ATOM 8365 C CE  . MET D 1 261 ? 116.838 134.138 125.650 1.00 57.20  ? 335 MET D CE  1 
ATOM 8366 N N   . ILE D 1 262 ? 119.599 139.555 123.165 1.00 33.80  ? 336 ILE D N   1 
ATOM 8367 C CA  . ILE D 1 262 ? 119.925 140.931 123.516 1.00 41.04  ? 336 ILE D CA  1 
ATOM 8368 C C   . ILE D 1 262 ? 118.705 141.806 123.271 1.00 47.23  ? 336 ILE D C   1 
ATOM 8369 O O   . ILE D 1 262 ? 118.079 141.729 122.207 1.00 58.06  ? 336 ILE D O   1 
ATOM 8370 C CB  . ILE D 1 262 ? 121.132 141.438 122.710 1.00 51.78  ? 336 ILE D CB  1 
ATOM 8371 C CG1 . ILE D 1 262 ? 122.369 140.595 123.015 1.00 53.82  ? 336 ILE D CG1 1 
ATOM 8372 C CG2 . ILE D 1 262 ? 121.398 142.902 123.013 1.00 54.74  ? 336 ILE D CG2 1 
ATOM 8373 C CD1 . ILE D 1 262 ? 123.663 141.220 122.561 1.00 53.37  ? 336 ILE D CD1 1 
ATOM 8374 N N   . HIS D 1 263 ? 118.365 142.632 124.253 1.00 47.22  ? 337 HIS D N   1 
ATOM 8375 C CA  . HIS D 1 263 ? 117.276 143.581 124.087 1.00 47.40  ? 337 HIS D CA  1 
ATOM 8376 C C   . HIS D 1 263 ? 117.659 144.639 123.054 1.00 52.03  ? 337 HIS D C   1 
ATOM 8377 O O   . HIS D 1 263 ? 118.813 145.076 123.012 1.00 59.10  ? 337 HIS D O   1 
ATOM 8378 C CB  . HIS D 1 263 ? 116.943 144.240 125.424 1.00 50.10  ? 337 HIS D CB  1 
ATOM 8379 C CG  . HIS D 1 263 ? 115.710 145.086 125.394 1.00 54.20  ? 337 HIS D CG  1 
ATOM 8380 N ND1 . HIS D 1 263 ? 115.722 146.404 124.994 1.00 56.13  ? 337 HIS D ND1 1 
ATOM 8381 C CD2 . HIS D 1 263 ? 114.427 144.805 125.719 1.00 57.69  ? 337 HIS D CD2 1 
ATOM 8382 C CE1 . HIS D 1 263 ? 114.500 146.898 125.072 1.00 53.05  ? 337 HIS D CE1 1 
ATOM 8383 N NE2 . HIS D 1 263 ? 113.695 145.947 125.508 1.00 55.76  ? 337 HIS D NE2 1 
ATOM 8384 N N   . PRO D 1 264 ? 116.719 145.073 122.209 1.00 48.02  ? 338 PRO D N   1 
ATOM 8385 C CA  . PRO D 1 264 ? 117.068 145.999 121.122 1.00 47.74  ? 338 PRO D CA  1 
ATOM 8386 C C   . PRO D 1 264 ? 117.441 147.403 121.572 1.00 49.30  ? 338 PRO D C   1 
ATOM 8387 O O   . PRO D 1 264 ? 117.727 148.245 120.713 1.00 52.69  ? 338 PRO D O   1 
ATOM 8388 C CB  . PRO D 1 264 ? 115.797 146.015 120.261 1.00 51.19  ? 338 PRO D CB  1 
ATOM 8389 C CG  . PRO D 1 264 ? 114.715 145.601 121.170 1.00 51.37  ? 338 PRO D CG  1 
ATOM 8390 C CD  . PRO D 1 264 ? 115.325 144.613 122.108 1.00 50.05  ? 338 PRO D CD  1 
ATOM 8391 N N   . ASN D 1 265 ? 117.455 147.696 122.868 1.00 59.11  ? 339 ASN D N   1 
ATOM 8392 C CA  . ASN D 1 265 ? 117.942 148.980 123.356 1.00 59.58  ? 339 ASN D CA  1 
ATOM 8393 C C   . ASN D 1 265 ? 119.390 148.925 123.824 1.00 55.99  ? 339 ASN D C   1 
ATOM 8394 O O   . ASN D 1 265 ? 119.905 149.936 124.312 1.00 59.86  ? 339 ASN D O   1 
ATOM 8395 C CB  . ASN D 1 265 ? 117.052 149.491 124.492 1.00 58.43  ? 339 ASN D CB  1 
ATOM 8396 C CG  . ASN D 1 265 ? 115.773 150.126 123.988 1.00 63.99  ? 339 ASN D CG  1 
ATOM 8397 O OD1 . ASN D 1 265 ? 115.722 150.644 122.875 1.00 63.29  ? 339 ASN D OD1 1 
ATOM 8398 N ND2 . ASN D 1 265 ? 114.732 150.091 124.810 1.00 65.69  ? 339 ASN D ND2 1 
ATOM 8399 N N   . VAL D 1 266 ? 120.052 147.782 123.690 1.00 53.31  ? 340 VAL D N   1 
ATOM 8400 C CA  . VAL D 1 266 ? 121.462 147.643 124.039 1.00 49.35  ? 340 VAL D CA  1 
ATOM 8401 C C   . VAL D 1 266 ? 122.288 147.997 122.806 1.00 60.88  ? 340 VAL D C   1 
ATOM 8402 O O   . VAL D 1 266 ? 122.179 147.301 121.785 1.00 69.98  ? 340 VAL D O   1 
ATOM 8403 C CB  . VAL D 1 266 ? 121.782 146.224 124.520 1.00 47.84  ? 340 VAL D CB  1 
ATOM 8404 C CG1 . VAL D 1 266 ? 123.249 146.112 124.892 1.00 56.86  ? 340 VAL D CG1 1 
ATOM 8405 C CG2 . VAL D 1 266 ? 120.898 145.853 125.696 1.00 56.00  ? 340 VAL D CG2 1 
ATOM 8406 N N   . PRO D 1 267 ? 123.108 149.041 122.853 1.00 51.69  ? 341 PRO D N   1 
ATOM 8407 C CA  . PRO D 1 267 ? 123.909 149.410 121.679 1.00 47.04  ? 341 PRO D CA  1 
ATOM 8408 C C   . PRO D 1 267 ? 125.165 148.568 121.521 1.00 51.18  ? 341 PRO D C   1 
ATOM 8409 O O   . PRO D 1 267 ? 126.239 148.962 121.987 1.00 54.80  ? 341 PRO D O   1 
ATOM 8410 C CB  . PRO D 1 267 ? 124.246 150.880 121.944 1.00 47.69  ? 341 PRO D CB  1 
ATOM 8411 C CG  . PRO D 1 267 ? 124.256 150.989 123.425 1.00 45.91  ? 341 PRO D CG  1 
ATOM 8412 C CD  . PRO D 1 267 ? 123.216 150.034 123.935 1.00 47.56  ? 341 PRO D CD  1 
ATOM 8413 N N   . ALA D 1 268 ? 125.051 147.408 120.877 1.00 45.00  ? 342 ALA D N   1 
ATOM 8414 C CA  . ALA D 1 268 ? 126.197 146.524 120.728 1.00 44.46  ? 342 ALA D CA  1 
ATOM 8415 C C   . ALA D 1 268 ? 126.048 145.678 119.470 1.00 39.67  ? 342 ALA D C   1 
ATOM 8416 O O   . ALA D 1 268 ? 124.959 145.557 118.904 1.00 41.17  ? 342 ALA D O   1 
ATOM 8417 C CB  . ALA D 1 268 ? 126.365 145.638 121.961 1.00 43.33  ? 342 ALA D CB  1 
ATOM 8418 N N   . ILE D 1 269 ? 127.166 145.096 119.037 1.00 38.92  ? 343 ILE D N   1 
ATOM 8419 C CA  . ILE D 1 269 ? 127.232 144.245 117.853 1.00 37.13  ? 343 ILE D CA  1 
ATOM 8420 C C   . ILE D 1 269 ? 127.675 142.857 118.293 1.00 39.90  ? 343 ILE D C   1 
ATOM 8421 O O   . ILE D 1 269 ? 128.647 142.723 119.044 1.00 49.37  ? 343 ILE D O   1 
ATOM 8422 C CB  . ILE D 1 269 ? 128.204 144.805 116.798 1.00 33.89  ? 343 ILE D CB  1 
ATOM 8423 C CG1 . ILE D 1 269 ? 127.774 146.194 116.339 1.00 39.82  ? 343 ILE D CG1 1 
ATOM 8424 C CG2 . ILE D 1 269 ? 128.288 143.876 115.605 1.00 38.02  ? 343 ILE D CG2 1 
ATOM 8425 C CD1 . ILE D 1 269 ? 128.701 146.784 115.305 1.00 43.78  ? 343 ILE D CD1 1 
ATOM 8426 N N   . MET D 1 270 ? 126.979 141.831 117.815 1.00 31.75  ? 344 MET D N   1 
ATOM 8427 C CA  . MET D 1 270 ? 127.237 140.458 118.222 1.00 32.28  ? 344 MET D CA  1 
ATOM 8428 C C   . MET D 1 270 ? 128.046 139.715 117.167 1.00 43.47  ? 344 MET D C   1 
ATOM 8429 O O   . MET D 1 270 ? 127.961 140.007 115.972 1.00 51.33  ? 344 MET D O   1 
ATOM 8430 C CB  . MET D 1 270 ? 125.929 139.710 118.471 1.00 32.24  ? 344 MET D CB  1 
ATOM 8431 C CG  . MET D 1 270 ? 124.908 140.496 119.254 1.00 42.28  ? 344 MET D CG  1 
ATOM 8432 S SD  . MET D 1 270 ? 123.361 139.596 119.403 1.00 66.94  ? 344 MET D SD  1 
ATOM 8433 C CE  . MET D 1 270 ? 123.914 138.119 120.248 1.00 48.71  ? 344 MET D CE  1 
ATOM 8434 N N   . ILE D 1 271 ? 128.840 138.750 117.626 1.00 31.70  ? 345 ILE D N   1 
ATOM 8435 C CA  . ILE D 1 271 ? 129.557 137.825 116.755 1.00 22.89  ? 345 ILE D CA  1 
ATOM 8436 C C   . ILE D 1 271 ? 129.270 136.412 117.240 1.00 28.52  ? 345 ILE D C   1 
ATOM 8437 O O   . ILE D 1 271 ? 129.620 136.059 118.372 1.00 35.42  ? 345 ILE D O   1 
ATOM 8438 C CB  . ILE D 1 271 ? 131.069 138.095 116.734 1.00 18.93  ? 345 ILE D CB  1 
ATOM 8439 C CG1 . ILE D 1 271 ? 131.352 139.483 116.161 1.00 20.70  ? 345 ILE D CG1 1 
ATOM 8440 C CG2 . ILE D 1 271 ? 131.783 137.038 115.921 1.00 32.76  ? 345 ILE D CG2 1 
ATOM 8441 C CD1 . ILE D 1 271 ? 132.815 139.830 116.109 1.00 33.70  ? 345 ILE D CD1 1 
ATOM 8442 N N   . THR D 1 272 ? 128.636 135.606 116.389 1.00 36.01  ? 346 THR D N   1 
ATOM 8443 C CA  . THR D 1 272 ? 128.206 134.268 116.760 1.00 30.04  ? 346 THR D CA  1 
ATOM 8444 C C   . THR D 1 272 ? 128.607 133.276 115.676 1.00 41.61  ? 346 THR D C   1 
ATOM 8445 O O   . THR D 1 272 ? 128.240 133.456 114.502 1.00 49.21  ? 346 THR D O   1 
ATOM 8446 C CB  . THR D 1 272 ? 126.692 134.224 116.981 1.00 33.66  ? 346 THR D CB  1 
ATOM 8447 O OG1 . THR D 1 272 ? 126.323 135.203 117.959 1.00 43.60  ? 346 THR D OG1 1 
ATOM 8448 C CG2 . THR D 1 272 ? 126.267 132.852 117.467 1.00 34.13  ? 346 THR D CG2 1 
ATOM 8449 N N   . PRO D 1 273 ? 129.345 132.226 116.018 1.00 42.96  ? 347 PRO D N   1 
ATOM 8450 C CA  . PRO D 1 273 ? 129.738 131.226 115.024 1.00 43.66  ? 347 PRO D CA  1 
ATOM 8451 C C   . PRO D 1 273 ? 128.601 130.259 114.720 1.00 47.16  ? 347 PRO D C   1 
ATOM 8452 O O   . PRO D 1 273 ? 127.601 130.182 115.432 1.00 56.42  ? 347 PRO D O   1 
ATOM 8453 C CB  . PRO D 1 273 ? 130.897 130.501 115.707 1.00 37.80  ? 347 PRO D CB  1 
ATOM 8454 C CG  . PRO D 1 273 ? 130.571 130.606 117.150 1.00 40.40  ? 347 PRO D CG  1 
ATOM 8455 C CD  . PRO D 1 273 ? 129.933 131.950 117.338 1.00 38.99  ? 347 PRO D CD  1 
ATOM 8456 N N   . ILE D 1 274 ? 128.779 129.509 113.636 1.00 44.28  ? 348 ILE D N   1 
ATOM 8457 C CA  . ILE D 1 274 ? 127.866 128.435 113.264 1.00 45.31  ? 348 ILE D CA  1 
ATOM 8458 C C   . ILE D 1 274 ? 128.654 127.143 113.412 1.00 53.03  ? 348 ILE D C   1 
ATOM 8459 O O   . ILE D 1 274 ? 129.526 126.845 112.587 1.00 56.40  ? 348 ILE D O   1 
ATOM 8460 C CB  . ILE D 1 274 ? 127.329 128.584 111.838 1.00 48.46  ? 348 ILE D CB  1 
ATOM 8461 C CG1 . ILE D 1 274 ? 126.610 129.909 111.667 1.00 47.35  ? 348 ILE D CG1 1 
ATOM 8462 C CG2 . ILE D 1 274 ? 126.339 127.474 111.542 1.00 50.32  ? 348 ILE D CG2 1 
ATOM 8463 C CD1 . ILE D 1 274 ? 126.261 130.224 110.231 1.00 51.81  ? 348 ILE D CD1 1 
ATOM 8464 N N   . CYS D 1 275 ? 128.351 126.373 114.452 1.00 54.39  ? 349 CYS D N   1 
ATOM 8465 C CA  . CYS D 1 275 ? 129.014 125.102 114.711 1.00 51.97  ? 349 CYS D CA  1 
ATOM 8466 C C   . CYS D 1 275 ? 130.531 125.256 114.695 1.00 54.42  ? 349 CYS D C   1 
ATOM 8467 O O   . CYS D 1 275 ? 131.196 124.702 113.811 1.00 61.56  ? 349 CYS D O   1 
ATOM 8468 C CB  . CYS D 1 275 ? 128.579 124.057 113.682 1.00 56.71  ? 349 CYS D CB  1 
ATOM 8469 S SG  . CYS D 1 275 ? 126.809 123.712 113.673 1.00 58.95  ? 349 CYS D SG  1 
ATOM 8470 N N   . PRO D 1 276 ? 131.113 126.001 115.632 1.00 54.11  ? 350 PRO D N   1 
ATOM 8471 C CA  . PRO D 1 276 ? 132.569 126.158 115.641 1.00 52.45  ? 350 PRO D CA  1 
ATOM 8472 C C   . PRO D 1 276 ? 133.271 124.843 115.933 1.00 55.88  ? 350 PRO D C   1 
ATOM 8473 O O   . PRO D 1 276 ? 132.774 123.996 116.678 1.00 57.99  ? 350 PRO D O   1 
ATOM 8474 C CB  . PRO D 1 276 ? 132.808 127.176 116.759 1.00 57.92  ? 350 PRO D CB  1 
ATOM 8475 C CG  . PRO D 1 276 ? 131.656 126.989 117.671 1.00 58.36  ? 350 PRO D CG  1 
ATOM 8476 C CD  . PRO D 1 276 ? 130.486 126.660 116.791 1.00 59.13  ? 350 PRO D CD  1 
ATOM 8477 N N   . HIS D 1 277 ? 134.450 124.680 115.331 1.00 63.38  ? 351 HIS D N   1 
ATOM 8478 C CA  . HIS D 1 277 ? 135.213 123.453 115.530 1.00 64.56  ? 351 HIS D CA  1 
ATOM 8479 C C   . HIS D 1 277 ? 135.742 123.354 116.955 1.00 69.40  ? 351 HIS D C   1 
ATOM 8480 O O   . HIS D 1 277 ? 135.768 122.264 117.539 1.00 72.37  ? 351 HIS D O   1 
ATOM 8481 C CB  . HIS D 1 277 ? 136.359 123.379 114.524 1.00 65.85  ? 351 HIS D CB  1 
ATOM 8482 C CG  . HIS D 1 277 ? 137.203 122.152 114.661 1.00 74.20  ? 351 HIS D CG  1 
ATOM 8483 N ND1 . HIS D 1 277 ? 136.731 120.888 114.379 1.00 74.25  ? 351 HIS D ND1 1 
ATOM 8484 C CD2 . HIS D 1 277 ? 138.490 121.994 115.053 1.00 74.25  ? 351 HIS D CD2 1 
ATOM 8485 C CE1 . HIS D 1 277 ? 137.691 120.004 114.589 1.00 75.63  ? 351 HIS D CE1 1 
ATOM 8486 N NE2 . HIS D 1 277 ? 138.768 120.649 114.998 1.00 73.63  ? 351 HIS D NE2 1 
ATOM 8487 N N   . SER D 1 278 ? 136.166 124.475 117.531 1.00 65.16  ? 352 SER D N   1 
ATOM 8488 C CA  . SER D 1 278 ? 136.687 124.499 118.891 1.00 62.34  ? 352 SER D CA  1 
ATOM 8489 C C   . SER D 1 278 ? 135.536 124.572 119.884 1.00 60.12  ? 352 SER D C   1 
ATOM 8490 O O   . SER D 1 278 ? 134.640 125.410 119.744 1.00 64.97  ? 352 SER D O   1 
ATOM 8491 C CB  . SER D 1 278 ? 137.630 125.685 119.086 1.00 64.63  ? 352 SER D CB  1 
ATOM 8492 O OG  . SER D 1 278 ? 136.945 126.911 118.904 1.00 62.39  ? 352 SER D OG  1 
ATOM 8493 N N   . LEU D 1 279 ? 135.567 123.694 120.888 1.00 58.26  ? 353 LEU D N   1 
ATOM 8494 C CA  . LEU D 1 279 ? 134.487 123.656 121.867 1.00 61.88  ? 353 LEU D CA  1 
ATOM 8495 C C   . LEU D 1 279 ? 134.462 124.910 122.730 1.00 61.54  ? 353 LEU D C   1 
ATOM 8496 O O   . LEU D 1 279 ? 133.394 125.312 123.205 1.00 62.21  ? 353 LEU D O   1 
ATOM 8497 C CB  . LEU D 1 279 ? 134.615 122.409 122.741 1.00 63.29  ? 353 LEU D CB  1 
ATOM 8498 C CG  . LEU D 1 279 ? 134.846 121.082 122.017 1.00 66.84  ? 353 LEU D CG  1 
ATOM 8499 C CD1 . LEU D 1 279 ? 134.941 119.943 123.017 1.00 63.51  ? 353 LEU D CD1 1 
ATOM 8500 C CD2 . LEU D 1 279 ? 133.742 120.818 121.007 1.00 64.40  ? 353 LEU D CD2 1 
ATOM 8501 N N   . SER D 1 280 ? 135.617 125.540 122.948 1.00 60.59  ? 354 SER D N   1 
ATOM 8502 C CA  . SER D 1 280 ? 135.695 126.778 123.721 1.00 62.07  ? 354 SER D CA  1 
ATOM 8503 C C   . SER D 1 280 ? 135.733 127.952 122.751 1.00 62.12  ? 354 SER D C   1 
ATOM 8504 O O   . SER D 1 280 ? 136.768 128.575 122.525 1.00 61.92  ? 354 SER D O   1 
ATOM 8505 C CB  . SER D 1 280 ? 136.918 126.780 124.632 1.00 61.13  ? 354 SER D CB  1 
ATOM 8506 O OG  . SER D 1 280 ? 138.114 126.680 123.880 1.00 62.50  ? 354 SER D OG  1 
ATOM 8507 N N   . PHE D 1 281 ? 134.575 128.253 122.165 1.00 59.22  ? 355 PHE D N   1 
ATOM 8508 C CA  . PHE D 1 281 ? 134.446 129.458 121.351 1.00 57.42  ? 355 PHE D CA  1 
ATOM 8509 C C   . PHE D 1 281 ? 133.002 129.933 121.501 1.00 52.85  ? 355 PHE D C   1 
ATOM 8510 O O   . PHE D 1 281 ? 132.125 129.500 120.750 1.00 56.16  ? 355 PHE D O   1 
ATOM 8511 C CB  . PHE D 1 281 ? 134.811 129.188 119.901 1.00 53.82  ? 355 PHE D CB  1 
ATOM 8512 C CG  . PHE D 1 281 ? 134.827 130.418 119.043 1.00 59.25  ? 355 PHE D CG  1 
ATOM 8513 C CD1 . PHE D 1 281 ? 135.859 131.333 119.148 1.00 59.73  ? 355 PHE D CD1 1 
ATOM 8514 C CD2 . PHE D 1 281 ? 133.824 130.654 118.125 1.00 61.27  ? 355 PHE D CD2 1 
ATOM 8515 C CE1 . PHE D 1 281 ? 135.882 132.466 118.360 1.00 61.36  ? 355 PHE D CE1 1 
ATOM 8516 C CE2 . PHE D 1 281 ? 133.842 131.786 117.334 1.00 60.12  ? 355 PHE D CE2 1 
ATOM 8517 C CZ  . PHE D 1 281 ? 134.870 132.692 117.451 1.00 61.83  ? 355 PHE D CZ  1 
ATOM 8518 N N   . ARG D 1 282 ? 132.784 130.799 122.439 1.00 51.21  ? 356 ARG D N   1 
ATOM 8519 C CA  . ARG D 1 282 ? 131.493 131.318 122.846 1.00 50.71  ? 356 ARG D CA  1 
ATOM 8520 C C   . ARG D 1 282 ? 131.184 132.612 122.106 1.00 56.92  ? 356 ARG D C   1 
ATOM 8521 O O   . ARG D 1 282 ? 132.096 133.379 121.784 1.00 62.77  ? 356 ARG D O   1 
ATOM 8522 C CB  . ARG D 1 282 ? 131.478 131.567 124.359 1.00 54.71  ? 356 ARG D CB  1 
ATOM 8523 C CG  . ARG D 1 282 ? 130.104 131.547 125.001 1.00 60.95  ? 356 ARG D CG  1 
ATOM 8524 C CD  . ARG D 1 282 ? 130.166 131.011 126.419 1.00 59.83  ? 356 ARG D CD  1 
ATOM 8525 N NE  . ARG D 1 282 ? 130.475 129.587 126.444 1.00 57.10  ? 356 ARG D NE  1 
ATOM 8526 C CZ  . ARG D 1 282 ? 130.444 128.834 127.534 1.00 60.47  ? 356 ARG D CZ  1 
ATOM 8527 N NH1 . ARG D 1 282 ? 130.128 129.340 128.715 1.00 59.54  ? 356 ARG D NH1 1 
ATOM 8528 N NH2 . ARG D 1 282 ? 130.738 127.541 127.438 1.00 59.64  ? 356 ARG D NH2 1 
ATOM 8529 N N   . PRO D 1 283 ? 129.914 132.871 121.799 1.00 35.13  ? 357 PRO D N   1 
ATOM 8530 C CA  . PRO D 1 283 ? 129.567 134.129 121.134 1.00 35.09  ? 357 PRO D CA  1 
ATOM 8531 C C   . PRO D 1 283 ? 129.985 135.327 121.971 1.00 34.25  ? 357 PRO D C   1 
ATOM 8532 O O   . PRO D 1 283 ? 129.873 135.323 123.198 1.00 44.30  ? 357 PRO D O   1 
ATOM 8533 C CB  . PRO D 1 283 ? 128.045 134.043 120.993 1.00 33.88  ? 357 PRO D CB  1 
ATOM 8534 C CG  . PRO D 1 283 ? 127.769 132.591 120.929 1.00 34.99  ? 357 PRO D CG  1 
ATOM 8535 C CD  . PRO D 1 283 ? 128.774 131.938 121.832 1.00 37.94  ? 357 PRO D CD  1 
ATOM 8536 N N   . ILE D 1 284 ? 130.476 136.356 121.292 1.00 19.03  ? 358 ILE D N   1 
ATOM 8537 C CA  . ILE D 1 284 ? 130.897 137.585 121.945 1.00 25.62  ? 358 ILE D CA  1 
ATOM 8538 C C   . ILE D 1 284 ? 130.073 138.730 121.384 1.00 33.49  ? 358 ILE D C   1 
ATOM 8539 O O   . ILE D 1 284 ? 129.557 138.661 120.265 1.00 40.29  ? 358 ILE D O   1 
ATOM 8540 C CB  . ILE D 1 284 ? 132.401 137.867 121.755 1.00 30.34  ? 358 ILE D CB  1 
ATOM 8541 C CG1 . ILE D 1 284 ? 132.723 138.057 120.276 1.00 27.19  ? 358 ILE D CG1 1 
ATOM 8542 C CG2 . ILE D 1 284 ? 133.229 136.733 122.324 1.00 36.40  ? 358 ILE D CG2 1 
ATOM 8543 C CD1 . ILE D 1 284 ? 134.128 138.538 120.019 1.00 33.99  ? 358 ILE D CD1 1 
ATOM 8544 N N   . VAL D 1 285 ? 129.947 139.790 122.175 1.00 40.36  ? 359 VAL D N   1 
ATOM 8545 C CA  . VAL D 1 285 ? 129.281 141.009 121.743 1.00 29.31  ? 359 VAL D CA  1 
ATOM 8546 C C   . VAL D 1 285 ? 130.223 142.177 122.004 1.00 31.46  ? 359 VAL D C   1 
ATOM 8547 O O   . VAL D 1 285 ? 130.870 142.247 123.055 1.00 47.42  ? 359 VAL D O   1 
ATOM 8548 C CB  . VAL D 1 285 ? 127.916 141.194 122.443 1.00 17.97  ? 359 VAL D CB  1 
ATOM 8549 C CG1 . VAL D 1 285 ? 128.080 141.448 123.913 1.00 29.43  ? 359 VAL D CG1 1 
ATOM 8550 C CG2 . VAL D 1 285 ? 127.121 142.290 121.781 1.00 35.42  ? 359 VAL D CG2 1 
ATOM 8551 N N   . VAL D 1 286 ? 130.330 143.069 121.031 1.00 24.76  ? 360 VAL D N   1 
ATOM 8552 C CA  . VAL D 1 286 ? 131.354 144.109 121.024 1.00 17.42  ? 360 VAL D CA  1 
ATOM 8553 C C   . VAL D 1 286 ? 130.642 145.453 120.997 1.00 27.28  ? 360 VAL D C   1 
ATOM 8554 O O   . VAL D 1 286 ? 129.451 145.530 120.652 1.00 44.11  ? 360 VAL D O   1 
ATOM 8555 C CB  . VAL D 1 286 ? 132.326 143.943 119.833 1.00 31.07  ? 360 VAL D CB  1 
ATOM 8556 C CG1 . VAL D 1 286 ? 133.019 142.599 119.907 1.00 31.32  ? 360 VAL D CG1 1 
ATOM 8557 C CG2 . VAL D 1 286 ? 131.582 144.084 118.520 1.00 42.56  ? 360 VAL D CG2 1 
ATOM 8558 N N   . PRO D 1 287 ? 131.329 146.535 121.374 1.00 17.85  ? 361 PRO D N   1 
ATOM 8559 C CA  . PRO D 1 287 ? 130.673 147.848 121.388 1.00 26.28  ? 361 PRO D CA  1 
ATOM 8560 C C   . PRO D 1 287 ? 130.156 148.235 120.011 1.00 40.63  ? 361 PRO D C   1 
ATOM 8561 O O   . PRO D 1 287 ? 130.688 147.817 118.982 1.00 45.62  ? 361 PRO D O   1 
ATOM 8562 C CB  . PRO D 1 287 ? 131.784 148.795 121.853 1.00 26.10  ? 361 PRO D CB  1 
ATOM 8563 C CG  . PRO D 1 287 ? 132.704 147.937 122.614 1.00 32.45  ? 361 PRO D CG  1 
ATOM 8564 C CD  . PRO D 1 287 ? 132.687 146.605 121.938 1.00 25.53  ? 361 PRO D CD  1 
ATOM 8565 N N   . ALA D 1 288 ? 129.088 149.035 120.006 1.00 36.65  ? 362 ALA D N   1 
ATOM 8566 C CA  . ALA D 1 288 ? 128.414 149.366 118.755 1.00 29.99  ? 362 ALA D CA  1 
ATOM 8567 C C   . ALA D 1 288 ? 129.311 150.151 117.808 1.00 38.42  ? 362 ALA D C   1 
ATOM 8568 O O   . ALA D 1 288 ? 129.303 149.899 116.598 1.00 42.61  ? 362 ALA D O   1 
ATOM 8569 C CB  . ALA D 1 288 ? 127.135 150.153 119.041 1.00 40.11  ? 362 ALA D CB  1 
ATOM 8570 N N   . GLY D 1 289 ? 130.087 151.097 118.329 1.00 46.00  ? 363 GLY D N   1 
ATOM 8571 C CA  . GLY D 1 289 ? 130.873 151.975 117.484 1.00 47.52  ? 363 GLY D CA  1 
ATOM 8572 C C   . GLY D 1 289 ? 132.184 151.388 117.008 1.00 52.11  ? 363 GLY D C   1 
ATOM 8573 O O   . GLY D 1 289 ? 133.173 152.112 116.858 1.00 56.70  ? 363 GLY D O   1 
ATOM 8574 N N   . VAL D 1 290 ? 132.210 150.085 116.763 1.00 50.25  ? 364 VAL D N   1 
ATOM 8575 C CA  . VAL D 1 290 ? 133.430 149.412 116.352 1.00 47.81  ? 364 VAL D CA  1 
ATOM 8576 C C   . VAL D 1 290 ? 133.381 149.174 114.847 1.00 53.03  ? 364 VAL D C   1 
ATOM 8577 O O   . VAL D 1 290 ? 132.312 149.118 114.234 1.00 53.87  ? 364 VAL D O   1 
ATOM 8578 C CB  . VAL D 1 290 ? 133.622 148.089 117.121 1.00 47.84  ? 364 VAL D CB  1 
ATOM 8579 C CG1 . VAL D 1 290 ? 132.600 147.058 116.675 1.00 49.25  ? 364 VAL D CG1 1 
ATOM 8580 C CG2 . VAL D 1 290 ? 135.030 147.577 116.970 1.00 55.36  ? 364 VAL D CG2 1 
ATOM 8581 N N   . GLU D 1 291 ? 134.557 149.044 114.240 1.00 57.37  ? 365 GLU D N   1 
ATOM 8582 C CA  . GLU D 1 291 ? 134.690 148.773 112.815 1.00 54.92  ? 365 GLU D CA  1 
ATOM 8583 C C   . GLU D 1 291 ? 135.192 147.347 112.629 1.00 53.75  ? 365 GLU D C   1 
ATOM 8584 O O   . GLU D 1 291 ? 136.375 147.069 112.849 1.00 56.82  ? 365 GLU D O   1 
ATOM 8585 C CB  . GLU D 1 291 ? 135.645 149.772 112.162 1.00 55.55  ? 365 GLU D CB  1 
ATOM 8586 C CG  . GLU D 1 291 ? 135.339 150.078 110.706 1.00 61.34  ? 365 GLU D CG  1 
ATOM 8587 C CD  . GLU D 1 291 ? 135.685 148.930 109.781 1.00 65.82  ? 365 GLU D CD  1 
ATOM 8588 O OE1 . GLU D 1 291 ? 136.657 148.202 110.070 1.00 63.02  ? 365 GLU D OE1 1 
ATOM 8589 O OE2 . GLU D 1 291 ? 134.983 148.755 108.763 1.00 65.24  ? 365 GLU D OE2 1 
ATOM 8590 N N   . LEU D 1 292 ? 134.296 146.451 112.230 1.00 47.37  ? 366 LEU D N   1 
ATOM 8591 C CA  . LEU D 1 292 ? 134.636 145.067 111.943 1.00 48.04  ? 366 LEU D CA  1 
ATOM 8592 C C   . LEU D 1 292 ? 135.112 144.920 110.504 1.00 54.10  ? 366 LEU D C   1 
ATOM 8593 O O   . LEU D 1 292 ? 134.828 145.753 109.641 1.00 61.48  ? 366 LEU D O   1 
ATOM 8594 C CB  . LEU D 1 292 ? 133.439 144.146 112.187 1.00 43.59  ? 366 LEU D CB  1 
ATOM 8595 C CG  . LEU D 1 292 ? 133.074 143.837 113.634 1.00 50.13  ? 366 LEU D CG  1 
ATOM 8596 C CD1 . LEU D 1 292 ? 131.749 143.109 113.691 1.00 60.45  ? 366 LEU D CD1 1 
ATOM 8597 C CD2 . LEU D 1 292 ? 134.161 142.999 114.268 1.00 55.25  ? 366 LEU D CD2 1 
ATOM 8598 N N   . LYS D 1 293 ? 135.844 143.838 110.256 1.00 47.10  ? 367 LYS D N   1 
ATOM 8599 C CA  . LYS D 1 293 ? 136.361 143.550 108.923 1.00 43.29  ? 367 LYS D CA  1 
ATOM 8600 C C   . LYS D 1 293 ? 136.640 142.059 108.832 1.00 47.80  ? 367 LYS D C   1 
ATOM 8601 O O   . LYS D 1 293 ? 137.528 141.551 109.521 1.00 55.82  ? 367 LYS D O   1 
ATOM 8602 C CB  . LYS D 1 293 ? 137.625 144.359 108.640 1.00 46.29  ? 367 LYS D CB  1 
ATOM 8603 C CG  . LYS D 1 293 ? 138.129 144.254 107.218 1.00 46.12  ? 367 LYS D CG  1 
ATOM 8604 C CD  . LYS D 1 293 ? 139.311 145.179 106.999 1.00 49.15  ? 367 LYS D CD  1 
ATOM 8605 C CE  . LYS D 1 293 ? 139.797 145.127 105.562 1.00 53.96  ? 367 LYS D CE  1 
ATOM 8606 N NZ  . LYS D 1 293 ? 140.217 143.754 105.169 1.00 55.68  ? 367 LYS D NZ  1 
ATOM 8607 N N   . ILE D 1 294 ? 135.885 141.364 107.986 1.00 40.05  ? 368 ILE D N   1 
ATOM 8608 C CA  . ILE D 1 294 ? 135.980 139.919 107.832 1.00 39.87  ? 368 ILE D CA  1 
ATOM 8609 C C   . ILE D 1 294 ? 136.508 139.621 106.436 1.00 49.72  ? 368 ILE D C   1 
ATOM 8610 O O   . ILE D 1 294 ? 135.958 140.110 105.443 1.00 55.26  ? 368 ILE D O   1 
ATOM 8611 C CB  . ILE D 1 294 ? 134.620 139.237 108.061 1.00 29.05  ? 368 ILE D CB  1 
ATOM 8612 C CG1 . ILE D 1 294 ? 134.184 139.384 109.515 1.00 37.06  ? 368 ILE D CG1 1 
ATOM 8613 C CG2 . ILE D 1 294 ? 134.684 137.777 107.682 1.00 39.22  ? 368 ILE D CG2 1 
ATOM 8614 C CD1 . ILE D 1 294 ? 132.881 138.699 109.822 1.00 45.14  ? 368 ILE D CD1 1 
ATOM 8615 N N   . MET D 1 295 ? 137.572 138.824 106.362 1.00 56.19  ? 369 MET D N   1 
ATOM 8616 C CA  . MET D 1 295 ? 138.178 138.476 105.087 1.00 45.46  ? 369 MET D CA  1 
ATOM 8617 C C   . MET D 1 295 ? 138.759 137.075 105.177 1.00 47.12  ? 369 MET D C   1 
ATOM 8618 O O   . MET D 1 295 ? 139.084 136.592 106.264 1.00 53.74  ? 369 MET D O   1 
ATOM 8619 C CB  . MET D 1 295 ? 139.266 139.479 104.690 1.00 52.67  ? 369 MET D CB  1 
ATOM 8620 C CG  . MET D 1 295 ? 140.383 139.617 105.711 1.00 60.11  ? 369 MET D CG  1 
ATOM 8621 S SD  . MET D 1 295 ? 141.554 140.921 105.293 1.00 67.05  ? 369 MET D SD  1 
ATOM 8622 C CE  . MET D 1 295 ? 142.085 140.389 103.669 1.00 53.91  ? 369 MET D CE  1 
ATOM 8623 N N   . LEU D 1 296 ? 138.896 136.432 104.020 1.00 47.55  ? 370 LEU D N   1 
ATOM 8624 C CA  . LEU D 1 296 ? 139.359 135.051 103.984 1.00 53.29  ? 370 LEU D CA  1 
ATOM 8625 C C   . LEU D 1 296 ? 140.806 134.945 104.440 1.00 62.75  ? 370 LEU D C   1 
ATOM 8626 O O   . LEU D 1 296 ? 141.636 135.810 104.147 1.00 71.46  ? 370 LEU D O   1 
ATOM 8627 C CB  . LEU D 1 296 ? 139.219 134.479 102.575 1.00 52.98  ? 370 LEU D CB  1 
ATOM 8628 C CG  . LEU D 1 296 ? 137.812 134.111 102.115 1.00 58.59  ? 370 LEU D CG  1 
ATOM 8629 C CD1 . LEU D 1 296 ? 137.874 133.368 100.793 1.00 58.36  ? 370 LEU D CD1 1 
ATOM 8630 C CD2 . LEU D 1 296 ? 137.112 133.275 103.169 1.00 64.36  ? 370 LEU D CD2 1 
ATOM 8631 N N   . SER D 1 297 ? 141.103 133.874 105.169 1.00 62.38  ? 371 SER D N   1 
ATOM 8632 C CA  . SER D 1 297 ? 142.471 133.613 105.579 1.00 60.71  ? 371 SER D CA  1 
ATOM 8633 C C   . SER D 1 297 ? 143.322 133.272 104.358 1.00 65.98  ? 371 SER D C   1 
ATOM 8634 O O   . SER D 1 297 ? 142.861 132.562 103.459 1.00 67.58  ? 371 SER D O   1 
ATOM 8635 C CB  . SER D 1 297 ? 142.520 132.469 106.588 1.00 64.86  ? 371 SER D CB  1 
ATOM 8636 O OG  . SER D 1 297 ? 142.012 131.273 106.022 1.00 67.76  ? 371 SER D OG  1 
ATOM 8637 N N   . PRO D 1 298 ? 144.558 133.768 104.291 1.00 66.03  ? 372 PRO D N   1 
ATOM 8638 C CA  . PRO D 1 298 ? 145.408 133.446 103.135 1.00 62.76  ? 372 PRO D CA  1 
ATOM 8639 C C   . PRO D 1 298 ? 145.700 131.964 102.990 1.00 61.88  ? 372 PRO D C   1 
ATOM 8640 O O   . PRO D 1 298 ? 145.884 131.486 101.863 1.00 65.21  ? 372 PRO D O   1 
ATOM 8641 C CB  . PRO D 1 298 ? 146.683 134.255 103.407 1.00 68.51  ? 372 PRO D CB  1 
ATOM 8642 C CG  . PRO D 1 298 ? 146.700 134.445 104.886 1.00 69.45  ? 372 PRO D CG  1 
ATOM 8643 C CD  . PRO D 1 298 ? 145.264 134.581 105.293 1.00 66.02  ? 372 PRO D CD  1 
ATOM 8644 N N   . GLU D 1 299 ? 145.746 131.218 104.092 1.00 74.76  ? 373 GLU D N   1 
ATOM 8645 C CA  . GLU D 1 299 ? 146.034 129.784 104.045 1.00 79.70  ? 373 GLU D CA  1 
ATOM 8646 C C   . GLU D 1 299 ? 144.720 129.001 104.020 1.00 79.90  ? 373 GLU D C   1 
ATOM 8647 O O   . GLU D 1 299 ? 144.367 128.262 104.941 1.00 80.42  ? 373 GLU D O   1 
ATOM 8648 C CB  . GLU D 1 299 ? 146.916 129.381 105.221 1.00 80.90  ? 373 GLU D CB  1 
ATOM 8649 C CG  . GLU D 1 299 ? 147.467 127.962 105.142 1.00 82.85  ? 373 GLU D CG  1 
ATOM 8650 C CD  . GLU D 1 299 ? 148.452 127.777 104.003 1.00 84.23  ? 373 GLU D CD  1 
ATOM 8651 O OE1 . GLU D 1 299 ? 149.079 128.773 103.586 1.00 85.34  ? 373 GLU D OE1 1 
ATOM 8652 O OE2 . GLU D 1 299 ? 148.599 126.632 103.524 1.00 83.03  ? 373 GLU D OE2 1 
ATOM 8653 N N   . ALA D 1 300 ? 143.985 129.191 102.929 1.00 65.30  ? 374 ALA D N   1 
ATOM 8654 C CA  . ALA D 1 300 ? 142.734 128.478 102.712 1.00 62.37  ? 374 ALA D CA  1 
ATOM 8655 C C   . ALA D 1 300 ? 142.455 128.443 101.218 1.00 64.28  ? 374 ALA D C   1 
ATOM 8656 O O   . ALA D 1 300 ? 142.883 129.323 100.468 1.00 62.01  ? 374 ALA D O   1 
ATOM 8657 C CB  . ALA D 1 300 ? 141.572 129.129 103.468 1.00 66.73  ? 374 ALA D CB  1 
ATOM 8658 N N   . ARG D 1 301 ? 141.722 127.414 100.797 1.00 76.88  ? 375 ARG D N   1 
ATOM 8659 C CA  . ARG D 1 301 ? 141.450 127.188 99.383  1.00 80.83  ? 375 ARG D CA  1 
ATOM 8660 C C   . ARG D 1 301 ? 139.996 127.431 99.016  1.00 81.44  ? 375 ARG D C   1 
ATOM 8661 O O   . ARG D 1 301 ? 139.717 128.222 98.106  1.00 84.07  ? 375 ARG D O   1 
ATOM 8662 C CB  . ARG D 1 301 ? 141.847 125.763 98.994  1.00 80.74  ? 375 ARG D CB  1 
ATOM 8663 C CG  . ARG D 1 301 ? 143.341 125.492 99.072  1.00 80.20  ? 375 ARG D CG  1 
ATOM 8664 C CD  . ARG D 1 301 ? 143.742 124.091 98.640  1.00 83.32  ? 375 ARG D CD  1 
ATOM 8665 N NE  . ARG D 1 301 ? 145.175 123.857 98.798  1.00 84.41  ? 375 ARG D NE  1 
ATOM 8666 C CZ  . ARG D 1 301 ? 145.764 122.687 98.604  1.00 82.32  ? 375 ARG D CZ  1 
ATOM 8667 N NH1 . ARG D 1 301 ? 145.047 121.632 98.237  1.00 80.28  ? 375 ARG D NH1 1 
ATOM 8668 N NH2 . ARG D 1 301 ? 147.075 122.566 98.772  1.00 81.83  ? 375 ARG D NH2 1 
ATOM 8669 N N   . ASN D 1 302 ? 139.059 126.774 99.692  1.00 72.91  ? 376 ASN D N   1 
ATOM 8670 C CA  . ASN D 1 302 ? 137.651 126.935 99.364  1.00 68.93  ? 376 ASN D CA  1 
ATOM 8671 C C   . ASN D 1 302 ? 137.169 128.329 99.740  1.00 65.01  ? 376 ASN D C   1 
ATOM 8672 O O   . ASN D 1 302 ? 137.430 128.821 100.840 1.00 69.33  ? 376 ASN D O   1 
ATOM 8673 C CB  . ASN D 1 302 ? 136.815 125.877 100.081 1.00 68.93  ? 376 ASN D CB  1 
ATOM 8674 C CG  . ASN D 1 302 ? 135.333 126.013 99.794  1.00 75.50  ? 376 ASN D CG  1 
ATOM 8675 O OD1 . ASN D 1 302 ? 134.852 125.596 98.740  1.00 74.62  ? 376 ASN D OD1 1 
ATOM 8676 N ND2 . ASN D 1 302 ? 134.598 126.595 100.735 1.00 76.77  ? 376 ASN D ND2 1 
ATOM 8677 N N   . THR D 1 303 ? 136.460 128.966 98.814  1.00 53.05  ? 377 THR D N   1 
ATOM 8678 C CA  . THR D 1 303 ? 135.933 130.300 99.040  1.00 53.54  ? 377 THR D CA  1 
ATOM 8679 C C   . THR D 1 303 ? 134.703 130.242 99.941  1.00 61.15  ? 377 THR D C   1 
ATOM 8680 O O   . THR D 1 303 ? 134.160 129.175 100.235 1.00 67.40  ? 377 THR D O   1 
ATOM 8681 C CB  . THR D 1 303 ? 135.587 130.972 97.715  1.00 60.36  ? 377 THR D CB  1 
ATOM 8682 O OG1 . THR D 1 303 ? 134.607 130.189 97.023  1.00 62.52  ? 377 THR D OG1 1 
ATOM 8683 C CG2 . THR D 1 303 ? 136.829 131.103 96.847  1.00 62.38  ? 377 THR D CG2 1 
ATOM 8684 N N   . ALA D 1 304 ? 134.266 131.417 100.384 1.00 63.11  ? 378 ALA D N   1 
ATOM 8685 C CA  . ALA D 1 304 ? 133.125 131.547 101.274 1.00 59.90  ? 378 ALA D CA  1 
ATOM 8686 C C   . ALA D 1 304 ? 132.047 132.399 100.620 1.00 54.11  ? 378 ALA D C   1 
ATOM 8687 O O   . ALA D 1 304 ? 132.308 133.165 99.689  1.00 60.55  ? 378 ALA D O   1 
ATOM 8688 C CB  . ALA D 1 304 ? 133.534 132.163 102.617 1.00 58.45  ? 378 ALA D CB  1 
ATOM 8689 N N   . TRP D 1 305 ? 130.826 132.256 101.123 1.00 44.30  ? 379 TRP D N   1 
ATOM 8690 C CA  . TRP D 1 305 ? 129.668 132.968 100.607 1.00 52.05  ? 379 TRP D CA  1 
ATOM 8691 C C   . TRP D 1 305 ? 129.081 133.837 101.707 1.00 55.51  ? 379 TRP D C   1 
ATOM 8692 O O   . TRP D 1 305 ? 129.040 133.432 102.872 1.00 66.15  ? 379 TRP D O   1 
ATOM 8693 C CB  . TRP D 1 305 ? 128.613 131.989 100.084 1.00 58.44  ? 379 TRP D CB  1 
ATOM 8694 C CG  . TRP D 1 305 ? 129.037 131.251 98.849  1.00 60.86  ? 379 TRP D CG  1 
ATOM 8695 C CD1 . TRP D 1 305 ? 129.763 130.102 98.794  1.00 56.23  ? 379 TRP D CD1 1 
ATOM 8696 C CD2 . TRP D 1 305 ? 128.740 131.603 97.493  1.00 50.57  ? 379 TRP D CD2 1 
ATOM 8697 N NE1 . TRP D 1 305 ? 129.947 129.720 97.490  1.00 55.66  ? 379 TRP D NE1 1 
ATOM 8698 C CE2 . TRP D 1 305 ? 129.326 130.624 96.671  1.00 48.31  ? 379 TRP D CE2 1 
ATOM 8699 C CE3 . TRP D 1 305 ? 128.035 132.650 96.895  1.00 47.27  ? 379 TRP D CE3 1 
ATOM 8700 C CZ2 . TRP D 1 305 ? 129.235 130.663 95.284  1.00 53.98  ? 379 TRP D CZ2 1 
ATOM 8701 C CZ3 . TRP D 1 305 ? 127.945 132.687 95.517  1.00 54.61  ? 379 TRP D CZ3 1 
ATOM 8702 C CH2 . TRP D 1 305 ? 128.541 131.700 94.727  1.00 58.14  ? 379 TRP D CH2 1 
ATOM 8703 N N   . VAL D 1 306 ? 128.623 135.030 101.335 1.00 32.99  ? 380 VAL D N   1 
ATOM 8704 C CA  . VAL D 1 306 ? 128.083 135.998 102.281 1.00 22.43  ? 380 VAL D CA  1 
ATOM 8705 C C   . VAL D 1 306 ? 126.618 136.244 101.950 1.00 34.96  ? 380 VAL D C   1 
ATOM 8706 O O   . VAL D 1 306 ? 126.241 136.331 100.776 1.00 51.51  ? 380 VAL D O   1 
ATOM 8707 C CB  . VAL D 1 306 ? 128.883 137.319 102.270 1.00 29.09  ? 380 VAL D CB  1 
ATOM 8708 C CG1 . VAL D 1 306 ? 128.854 137.965 100.899 1.00 36.53  ? 380 VAL D CG1 1 
ATOM 8709 C CG2 . VAL D 1 306 ? 128.353 138.272 103.324 1.00 40.33  ? 380 VAL D CG2 1 
ATOM 8710 N N   . SER D 1 307 ? 125.790 136.331 102.988 1.00 39.24  ? 381 SER D N   1 
ATOM 8711 C CA  . SER D 1 307 ? 124.370 136.608 102.841 1.00 42.71  ? 381 SER D CA  1 
ATOM 8712 C C   . SER D 1 307 ? 123.989 137.786 103.723 1.00 43.59  ? 381 SER D C   1 
ATOM 8713 O O   . SER D 1 307 ? 124.575 137.999 104.787 1.00 53.10  ? 381 SER D O   1 
ATOM 8714 C CB  . SER D 1 307 ? 123.522 135.388 103.205 1.00 47.53  ? 381 SER D CB  1 
ATOM 8715 O OG  . SER D 1 307 ? 123.738 135.004 104.550 1.00 48.94  ? 381 SER D OG  1 
ATOM 8716 N N   . PHE D 1 308 ? 122.996 138.550 103.274 1.00 40.04  ? 382 PHE D N   1 
ATOM 8717 C CA  . PHE D 1 308 ? 122.527 139.739 103.984 1.00 45.06  ? 382 PHE D CA  1 
ATOM 8718 C C   . PHE D 1 308 ? 121.031 139.598 104.245 1.00 48.07  ? 382 PHE D C   1 
ATOM 8719 O O   . PHE D 1 308 ? 120.214 139.944 103.388 1.00 51.68  ? 382 PHE D O   1 
ATOM 8720 C CB  . PHE D 1 308 ? 122.826 141.004 103.187 1.00 44.57  ? 382 PHE D CB  1 
ATOM 8721 C CG  . PHE D 1 308 ? 124.239 141.091 102.690 1.00 45.70  ? 382 PHE D CG  1 
ATOM 8722 C CD1 . PHE D 1 308 ? 124.586 140.582 101.453 1.00 41.68  ? 382 PHE D CD1 1 
ATOM 8723 C CD2 . PHE D 1 308 ? 125.217 141.693 103.457 1.00 48.05  ? 382 PHE D CD2 1 
ATOM 8724 C CE1 . PHE D 1 308 ? 125.884 140.665 100.996 1.00 44.75  ? 382 PHE D CE1 1 
ATOM 8725 C CE2 . PHE D 1 308 ? 126.513 141.778 103.005 1.00 49.35  ? 382 PHE D CE2 1 
ATOM 8726 C CZ  . PHE D 1 308 ? 126.848 141.264 101.774 1.00 50.98  ? 382 PHE D CZ  1 
ATOM 8727 N N   . ASP D 1 309 ? 120.676 139.108 105.434 1.00 51.00  ? 383 ASP D N   1 
ATOM 8728 C CA  . ASP D 1 309 ? 119.279 138.926 105.833 1.00 51.81  ? 383 ASP D CA  1 
ATOM 8729 C C   . ASP D 1 309 ? 118.533 138.010 104.867 1.00 59.80  ? 383 ASP D C   1 
ATOM 8730 O O   . ASP D 1 309 ? 117.383 138.266 104.504 1.00 63.31  ? 383 ASP D O   1 
ATOM 8731 C CB  . ASP D 1 309 ? 118.555 140.268 105.965 1.00 56.34  ? 383 ASP D CB  1 
ATOM 8732 C CG  . ASP D 1 309 ? 119.045 141.082 107.139 1.00 61.85  ? 383 ASP D CG  1 
ATOM 8733 O OD1 . ASP D 1 309 ? 119.510 140.480 108.128 1.00 61.09  ? 383 ASP D OD1 1 
ATOM 8734 O OD2 . ASP D 1 309 ? 118.957 142.326 107.076 1.00 65.82  ? 383 ASP D OD2 1 
ATOM 8735 N N   . GLY D 1 310 ? 119.185 136.929 104.452 1.00 49.90  ? 384 GLY D N   1 
ATOM 8736 C CA  . GLY D 1 310 ? 118.573 136.001 103.523 1.00 47.40  ? 384 GLY D CA  1 
ATOM 8737 C C   . GLY D 1 310 ? 118.308 136.622 102.168 1.00 50.90  ? 384 GLY D C   1 
ATOM 8738 O O   . GLY D 1 310 ? 117.247 136.417 101.572 1.00 56.45  ? 384 GLY D O   1 
ATOM 8739 N N   . ARG D 1 311 ? 119.277 137.387 101.675 1.00 48.69  ? 385 ARG D N   1 
ATOM 8740 C CA  . ARG D 1 311 ? 119.165 138.064 100.391 1.00 45.38  ? 385 ARG D CA  1 
ATOM 8741 C C   . ARG D 1 311 ? 120.348 137.682 99.518  1.00 48.45  ? 385 ARG D C   1 
ATOM 8742 O O   . ARG D 1 311 ? 121.043 136.705 99.813  1.00 55.70  ? 385 ARG D O   1 
ATOM 8743 C CB  . ARG D 1 311 ? 119.093 139.579 100.565 1.00 45.20  ? 385 ARG D CB  1 
ATOM 8744 C CG  . ARG D 1 311 ? 117.791 140.069 101.165 1.00 51.72  ? 385 ARG D CG  1 
ATOM 8745 C CD  . ARG D 1 311 ? 117.817 141.572 101.376 1.00 51.39  ? 385 ARG D CD  1 
ATOM 8746 N NE  . ARG D 1 311 ? 118.043 142.305 100.136 1.00 53.22  ? 385 ARG D NE  1 
ATOM 8747 C CZ  . ARG D 1 311 ? 118.471 143.558 100.078 1.00 53.97  ? 385 ARG D CZ  1 
ATOM 8748 N NH1 . ARG D 1 311 ? 118.765 144.238 101.174 1.00 54.81  ? 385 ARG D NH1 1 
ATOM 8749 N NH2 . ARG D 1 311 ? 118.615 144.141 98.892  1.00 50.23  ? 385 ARG D NH2 1 
ATOM 8750 N N   . LYS D 1 312 ? 120.546 138.426 98.430  1.00 48.33  ? 386 LYS D N   1 
ATOM 8751 C CA  . LYS D 1 312 ? 121.556 138.129 97.419  1.00 54.54  ? 386 LYS D CA  1 
ATOM 8752 C C   . LYS D 1 312 ? 122.849 137.598 98.028  1.00 58.53  ? 386 LYS D C   1 
ATOM 8753 O O   . LYS D 1 312 ? 123.410 138.188 98.955  1.00 63.92  ? 386 LYS D O   1 
ATOM 8754 C CB  . LYS D 1 312 ? 121.831 139.388 96.588  1.00 58.66  ? 386 LYS D CB  1 
ATOM 8755 C CG  . LYS D 1 312 ? 122.442 140.553 97.356  1.00 56.85  ? 386 LYS D CG  1 
ATOM 8756 C CD  . LYS D 1 312 ? 122.571 141.789 96.479  1.00 62.53  ? 386 LYS D CD  1 
ATOM 8757 C CE  . LYS D 1 312 ? 123.661 141.618 95.432  1.00 64.44  ? 386 LYS D CE  1 
ATOM 8758 N NZ  . LYS D 1 312 ? 123.866 142.856 94.629  1.00 61.38  ? 386 LYS D NZ  1 
ATOM 8759 N N   . ARG D 1 313 ? 123.293 136.454 97.520  1.00 46.03  ? 387 ARG D N   1 
ATOM 8760 C CA  . ARG D 1 313 ? 124.510 135.802 97.976  1.00 32.71  ? 387 ARG D CA  1 
ATOM 8761 C C   . ARG D 1 313 ? 125.600 135.973 96.931  1.00 39.88  ? 387 ARG D C   1 
ATOM 8762 O O   . ARG D 1 313 ? 125.372 135.753 95.738  1.00 53.28  ? 387 ARG D O   1 
ATOM 8763 C CB  . ARG D 1 313 ? 124.275 134.316 98.229  1.00 34.09  ? 387 ARG D CB  1 
ATOM 8764 C CG  . ARG D 1 313 ? 123.130 134.020 99.158  1.00 38.49  ? 387 ARG D CG  1 
ATOM 8765 C CD  . ARG D 1 313 ? 122.831 132.540 99.158  1.00 41.39  ? 387 ARG D CD  1 
ATOM 8766 N NE  . ARG D 1 313 ? 123.986 131.761 99.581  1.00 41.84  ? 387 ARG D NE  1 
ATOM 8767 C CZ  . ARG D 1 313 ? 124.003 130.439 99.671  1.00 45.21  ? 387 ARG D CZ  1 
ATOM 8768 N NH1 . ARG D 1 313 ? 122.946 129.712 99.351  1.00 48.33  ? 387 ARG D NH1 1 
ATOM 8769 N NH2 . ARG D 1 313 ? 125.106 129.833 100.094 1.00 41.71  ? 387 ARG D NH2 1 
ATOM 8770 N N   . GLN D 1 314 ? 126.785 136.364 97.384  1.00 38.12  ? 388 GLN D N   1 
ATOM 8771 C CA  . GLN D 1 314 ? 127.913 136.540 96.487  1.00 49.39  ? 388 GLN D CA  1 
ATOM 8772 C C   . GLN D 1 314 ? 129.143 135.920 97.124  1.00 58.19  ? 388 GLN D C   1 
ATOM 8773 O O   . GLN D 1 314 ? 129.407 136.123 98.311  1.00 62.36  ? 388 GLN D O   1 
ATOM 8774 C CB  . GLN D 1 314 ? 128.144 138.021 96.164  1.00 51.35  ? 388 GLN D CB  1 
ATOM 8775 C CG  . GLN D 1 314 ? 128.264 138.923 97.374  1.00 50.63  ? 388 GLN D CG  1 
ATOM 8776 C CD  . GLN D 1 314 ? 128.215 140.391 97.008  1.00 51.50  ? 388 GLN D CD  1 
ATOM 8777 O OE1 . GLN D 1 314 ? 127.144 140.992 96.953  1.00 53.50  ? 388 GLN D OE1 1 
ATOM 8778 N NE2 . GLN D 1 314 ? 129.379 140.978 96.760  1.00 58.38  ? 388 GLN D NE2 1 
ATOM 8779 N N   . GLU D 1 315 ? 129.881 135.150 96.332  1.00 54.17  ? 389 GLU D N   1 
ATOM 8780 C CA  . GLU D 1 315 ? 131.068 134.481 96.833  1.00 54.53  ? 389 GLU D CA  1 
ATOM 8781 C C   . GLU D 1 315 ? 132.188 135.487 97.040  1.00 56.85  ? 389 GLU D C   1 
ATOM 8782 O O   . GLU D 1 315 ? 132.399 136.384 96.220  1.00 57.95  ? 389 GLU D O   1 
ATOM 8783 C CB  . GLU D 1 315 ? 131.514 133.382 95.870  1.00 56.91  ? 389 GLU D CB  1 
ATOM 8784 C CG  . GLU D 1 315 ? 131.637 133.827 94.423  1.00 63.23  ? 389 GLU D CG  1 
ATOM 8785 C CD  . GLU D 1 315 ? 131.948 132.676 93.486  1.00 67.41  ? 389 GLU D CD  1 
ATOM 8786 O OE1 . GLU D 1 315 ? 132.234 131.565 93.981  1.00 67.20  ? 389 GLU D OE1 1 
ATOM 8787 O OE2 . GLU D 1 315 ? 131.908 132.882 92.255  1.00 66.80  ? 389 GLU D OE2 1 
ATOM 8788 N N   . ILE D 1 316 ? 132.899 135.341 98.152  1.00 49.98  ? 390 ILE D N   1 
ATOM 8789 C CA  . ILE D 1 316 ? 134.058 136.167 98.459  1.00 50.38  ? 390 ILE D CA  1 
ATOM 8790 C C   . ILE D 1 316 ? 135.296 135.286 98.363  1.00 65.12  ? 390 ILE D C   1 
ATOM 8791 O O   . ILE D 1 316 ? 135.365 134.217 98.983  1.00 68.02  ? 390 ILE D O   1 
ATOM 8792 C CB  . ILE D 1 316 ? 133.932 136.845 99.834  1.00 50.58  ? 390 ILE D CB  1 
ATOM 8793 C CG1 . ILE D 1 316 ? 133.805 135.819 100.960 1.00 56.24  ? 390 ILE D CG1 1 
ATOM 8794 C CG2 . ILE D 1 316 ? 132.746 137.795 99.848  1.00 60.07  ? 390 ILE D CG2 1 
ATOM 8795 C CD1 . ILE D 1 316 ? 133.912 136.423 102.338 1.00 60.56  ? 390 ILE D CD1 1 
ATOM 8796 N N   . ARG D 1 317 ? 136.247 135.711 97.544  1.00 65.96  ? 391 ARG D N   1 
ATOM 8797 C CA  . ARG D 1 317 ? 137.505 135.019 97.340  1.00 54.96  ? 391 ARG D CA  1 
ATOM 8798 C C   . ARG D 1 317 ? 138.606 135.738 98.117  1.00 62.14  ? 391 ARG D C   1 
ATOM 8799 O O   . ARG D 1 317 ? 138.339 136.607 98.953  1.00 66.38  ? 391 ARG D O   1 
ATOM 8800 C CB  . ARG D 1 317 ? 137.796 134.905 95.843  1.00 50.26  ? 391 ARG D CB  1 
ATOM 8801 C CG  . ARG D 1 317 ? 137.669 136.206 95.083  1.00 56.10  ? 391 ARG D CG  1 
ATOM 8802 C CD  . ARG D 1 317 ? 137.677 135.959 93.588  1.00 58.44  ? 391 ARG D CD  1 
ATOM 8803 N NE  . ARG D 1 317 ? 136.570 135.100 93.183  1.00 55.52  ? 391 ARG D NE  1 
ATOM 8804 C CZ  . ARG D 1 317 ? 135.360 135.539 92.868  1.00 58.51  ? 391 ARG D CZ  1 
ATOM 8805 N NH1 . ARG D 1 317 ? 135.060 136.826 92.904  1.00 56.06  ? 391 ARG D NH1 1 
ATOM 8806 N NH2 . ARG D 1 317 ? 134.425 134.664 92.511  1.00 61.04  ? 391 ARG D NH2 1 
ATOM 8807 N N   . HIS D 1 318 ? 139.859 135.355 97.858  1.00 65.30  ? 392 HIS D N   1 
ATOM 8808 C CA  . HIS D 1 318 ? 140.981 135.833 98.662  1.00 66.74  ? 392 HIS D CA  1 
ATOM 8809 C C   . HIS D 1 318 ? 141.048 137.355 98.714  1.00 69.10  ? 392 HIS D C   1 
ATOM 8810 O O   . HIS D 1 318 ? 141.317 137.935 99.772  1.00 77.36  ? 392 HIS D O   1 
ATOM 8811 C CB  . HIS D 1 318 ? 142.287 135.267 98.110  1.00 68.74  ? 392 HIS D CB  1 
ATOM 8812 C CG  . HIS D 1 318 ? 142.409 133.783 98.253  1.00 74.37  ? 392 HIS D CG  1 
ATOM 8813 N ND1 . HIS D 1 318 ? 141.933 132.903 97.305  1.00 76.95  ? 392 HIS D ND1 1 
ATOM 8814 C CD2 . HIS D 1 318 ? 142.954 133.023 99.232  1.00 77.32  ? 392 HIS D CD2 1 
ATOM 8815 C CE1 . HIS D 1 318 ? 142.179 131.665 97.694  1.00 76.80  ? 392 HIS D CE1 1 
ATOM 8816 N NE2 . HIS D 1 318 ? 142.798 131.710 98.860  1.00 78.13  ? 392 HIS D NE2 1 
ATOM 8817 N N   . GLY D 1 319 ? 140.810 138.020 97.587  1.00 55.37  ? 393 GLY D N   1 
ATOM 8818 C CA  . GLY D 1 319 ? 140.962 139.460 97.523  1.00 56.26  ? 393 GLY D CA  1 
ATOM 8819 C C   . GLY D 1 319 ? 139.805 140.284 98.038  1.00 56.40  ? 393 GLY D C   1 
ATOM 8820 O O   . GLY D 1 319 ? 139.892 141.514 98.045  1.00 58.08  ? 393 GLY D O   1 
ATOM 8821 N N   . ASP D 1 320 ? 138.724 139.649 98.474  1.00 57.81  ? 394 ASP D N   1 
ATOM 8822 C CA  . ASP D 1 320 ? 137.531 140.368 98.892  1.00 54.21  ? 394 ASP D CA  1 
ATOM 8823 C C   . ASP D 1 320 ? 137.468 140.484 100.410 1.00 57.60  ? 394 ASP D C   1 
ATOM 8824 O O   . ASP D 1 320 ? 137.897 139.589 101.141 1.00 65.07  ? 394 ASP D O   1 
ATOM 8825 C CB  . ASP D 1 320 ? 136.276 139.669 98.371  1.00 59.97  ? 394 ASP D CB  1 
ATOM 8826 C CG  . ASP D 1 320 ? 136.302 139.473 96.870  1.00 64.99  ? 394 ASP D CG  1 
ATOM 8827 O OD1 . ASP D 1 320 ? 137.050 140.206 96.190  1.00 65.49  ? 394 ASP D OD1 1 
ATOM 8828 O OD2 . ASP D 1 320 ? 135.579 138.586 96.371  1.00 67.72  ? 394 ASP D OD2 1 
ATOM 8829 N N   . SER D 1 321 ? 136.920 141.604 100.877 1.00 48.83  ? 395 SER D N   1 
ATOM 8830 C CA  . SER D 1 321 ? 136.764 141.858 102.300 1.00 51.43  ? 395 SER D CA  1 
ATOM 8831 C C   . SER D 1 321 ? 135.441 142.565 102.547 1.00 51.47  ? 395 SER D C   1 
ATOM 8832 O O   . SER D 1 321 ? 134.994 143.379 101.736 1.00 53.05  ? 395 SER D O   1 
ATOM 8833 C CB  . SER D 1 321 ? 137.918 142.704 102.850 1.00 56.63  ? 395 SER D CB  1 
ATOM 8834 O OG  . SER D 1 321 ? 137.765 142.925 104.241 1.00 59.15  ? 395 SER D OG  1 
ATOM 8835 N N   . ILE D 1 322 ? 134.820 142.250 103.681 1.00 47.90  ? 396 ILE D N   1 
ATOM 8836 C CA  . ILE D 1 322 ? 133.562 142.861 104.095 1.00 45.48  ? 396 ILE D CA  1 
ATOM 8837 C C   . ILE D 1 322 ? 133.805 143.627 105.389 1.00 46.94  ? 396 ILE D C   1 
ATOM 8838 O O   . ILE D 1 322 ? 134.459 143.118 106.306 1.00 52.88  ? 396 ILE D O   1 
ATOM 8839 C CB  . ILE D 1 322 ? 132.437 141.815 104.248 1.00 38.53  ? 396 ILE D CB  1 
ATOM 8840 C CG1 . ILE D 1 322 ? 131.090 142.506 104.466 1.00 53.18  ? 396 ILE D CG1 1 
ATOM 8841 C CG2 . ILE D 1 322 ? 132.728 140.823 105.356 1.00 43.94  ? 396 ILE D CG2 1 
ATOM 8842 C CD1 . ILE D 1 322 ? 129.901 141.584 104.311 1.00 54.74  ? 396 ILE D CD1 1 
ATOM 8843 N N   . SER D 1 323 ? 133.319 144.864 105.442 1.00 46.69  ? 397 SER D N   1 
ATOM 8844 C CA  . SER D 1 323 ? 133.491 145.738 106.595 1.00 49.14  ? 397 SER D CA  1 
ATOM 8845 C C   . SER D 1 323 ? 132.129 146.058 107.191 1.00 52.97  ? 397 SER D C   1 
ATOM 8846 O O   . SER D 1 323 ? 131.212 146.457 106.467 1.00 55.77  ? 397 SER D O   1 
ATOM 8847 C CB  . SER D 1 323 ? 134.213 147.027 106.203 1.00 55.52  ? 397 SER D CB  1 
ATOM 8848 O OG  . SER D 1 323 ? 133.479 147.743 105.226 1.00 62.45  ? 397 SER D OG  1 
ATOM 8849 N N   . ILE D 1 324 ? 132.005 145.901 108.506 1.00 47.17  ? 398 ILE D N   1 
ATOM 8850 C CA  . ILE D 1 324 ? 130.731 146.021 109.206 1.00 41.43  ? 398 ILE D CA  1 
ATOM 8851 C C   . ILE D 1 324 ? 130.847 147.125 110.247 1.00 46.95  ? 398 ILE D C   1 
ATOM 8852 O O   . ILE D 1 324 ? 131.813 147.161 111.017 1.00 54.14  ? 398 ILE D O   1 
ATOM 8853 C CB  . ILE D 1 324 ? 130.322 144.693 109.864 1.00 39.69  ? 398 ILE D CB  1 
ATOM 8854 C CG1 . ILE D 1 324 ? 130.432 143.551 108.857 1.00 49.62  ? 398 ILE D CG1 1 
ATOM 8855 C CG2 . ILE D 1 324 ? 128.909 144.783 110.403 1.00 54.36  ? 398 ILE D CG2 1 
ATOM 8856 C CD1 . ILE D 1 324 ? 130.175 142.196 109.451 1.00 50.82  ? 398 ILE D CD1 1 
ATOM 8857 N N   . THR D 1 325 ? 129.864 148.021 110.265 1.00 48.92  ? 399 THR D N   1 
ATOM 8858 C CA  . THR D 1 325 ? 129.848 149.152 111.180 1.00 51.30  ? 399 THR D CA  1 
ATOM 8859 C C   . THR D 1 325 ? 128.398 149.518 111.464 1.00 47.59  ? 399 THR D C   1 
ATOM 8860 O O   . THR D 1 325 ? 127.535 149.394 110.591 1.00 50.55  ? 399 THR D O   1 
ATOM 8861 C CB  . THR D 1 325 ? 130.606 150.351 110.593 1.00 58.82  ? 399 THR D CB  1 
ATOM 8862 O OG1 . THR D 1 325 ? 131.962 149.975 110.325 1.00 60.44  ? 399 THR D OG1 1 
ATOM 8863 C CG2 . THR D 1 325 ? 130.607 151.526 111.560 1.00 57.36  ? 399 THR D CG2 1 
ATOM 8864 N N   . THR D 1 326 ? 128.134 149.958 112.693 1.00 45.09  ? 400 THR D N   1 
ATOM 8865 C CA  . THR D 1 326 ? 126.780 150.343 113.071 1.00 49.23  ? 400 THR D CA  1 
ATOM 8866 C C   . THR D 1 326 ? 126.304 151.515 112.223 1.00 56.41  ? 400 THR D C   1 
ATOM 8867 O O   . THR D 1 326 ? 127.019 152.506 112.049 1.00 56.70  ? 400 THR D O   1 
ATOM 8868 C CB  . THR D 1 326 ? 126.726 150.708 114.553 1.00 42.91  ? 400 THR D CB  1 
ATOM 8869 O OG1 . THR D 1 326 ? 127.165 149.593 115.337 1.00 49.98  ? 400 THR D OG1 1 
ATOM 8870 C CG2 . THR D 1 326 ? 125.310 151.071 114.961 1.00 43.96  ? 400 THR D CG2 1 
ATOM 8871 N N   . SER D 1 327 ? 125.089 151.398 111.695 1.00 57.54  ? 401 SER D N   1 
ATOM 8872 C CA  . SER D 1 327 ? 124.521 152.421 110.835 1.00 50.30  ? 401 SER D CA  1 
ATOM 8873 C C   . SER D 1 327 ? 124.076 153.632 111.647 1.00 53.03  ? 401 SER D C   1 
ATOM 8874 O O   . SER D 1 327 ? 123.794 153.546 112.844 1.00 53.56  ? 401 SER D O   1 
ATOM 8875 C CB  . SER D 1 327 ? 123.336 151.862 110.047 1.00 53.56  ? 401 SER D CB  1 
ATOM 8876 O OG  . SER D 1 327 ? 122.773 152.849 109.201 1.00 59.39  ? 401 SER D OG  1 
ATOM 8877 N N   . THR D 1 328 ? 124.020 154.776 110.971 1.00 61.78  ? 402 THR D N   1 
ATOM 8878 C CA  . THR D 1 328 ? 123.506 156.008 111.550 1.00 60.89  ? 402 THR D CA  1 
ATOM 8879 C C   . THR D 1 328 ? 122.031 156.225 111.242 1.00 61.14  ? 402 THR D C   1 
ATOM 8880 O O   . THR D 1 328 ? 121.479 157.266 111.609 1.00 59.92  ? 402 THR D O   1 
ATOM 8881 C CB  . THR D 1 328 ? 124.319 157.206 111.054 1.00 66.10  ? 402 THR D CB  1 
ATOM 8882 O OG1 . THR D 1 328 ? 124.251 157.272 109.625 1.00 64.82  ? 402 THR D OG1 1 
ATOM 8883 C CG2 . THR D 1 328 ? 125.773 157.077 111.482 1.00 64.05  ? 402 THR D CG2 1 
ATOM 8884 N N   . TYR D 1 329 ? 121.384 155.265 110.581 1.00 61.94  ? 403 TYR D N   1 
ATOM 8885 C CA  . TYR D 1 329 ? 119.978 155.363 110.192 1.00 60.79  ? 403 TYR D CA  1 
ATOM 8886 C C   . TYR D 1 329 ? 119.233 154.181 110.794 1.00 66.72  ? 403 TYR D C   1 
ATOM 8887 O O   . TYR D 1 329 ? 119.080 153.132 110.153 1.00 68.60  ? 403 TYR D O   1 
ATOM 8888 C CB  . TYR D 1 329 ? 119.827 155.397 108.671 1.00 56.70  ? 403 TYR D CB  1 
ATOM 8889 C CG  . TYR D 1 329 ? 120.610 156.502 108.003 1.00 58.97  ? 403 TYR D CG  1 
ATOM 8890 C CD1 . TYR D 1 329 ? 120.113 157.796 107.948 1.00 64.39  ? 403 TYR D CD1 1 
ATOM 8891 C CD2 . TYR D 1 329 ? 121.846 156.250 107.425 1.00 63.17  ? 403 TYR D CD2 1 
ATOM 8892 C CE1 . TYR D 1 329 ? 120.825 158.809 107.338 1.00 65.43  ? 403 TYR D CE1 1 
ATOM 8893 C CE2 . TYR D 1 329 ? 122.565 157.257 106.813 1.00 68.28  ? 403 TYR D CE2 1 
ATOM 8894 C CZ  . TYR D 1 329 ? 122.051 158.534 106.772 1.00 67.00  ? 403 TYR D CZ  1 
ATOM 8895 O OH  . TYR D 1 329 ? 122.765 159.540 106.163 1.00 64.05  ? 403 TYR D OH  1 
ATOM 8896 N N   . PRO D 1 330 ? 118.752 154.315 112.027 1.00 55.84  ? 404 PRO D N   1 
ATOM 8897 C CA  . PRO D 1 330 ? 118.062 153.199 112.676 1.00 52.16  ? 404 PRO D CA  1 
ATOM 8898 C C   . PRO D 1 330 ? 116.657 153.003 112.127 1.00 59.62  ? 404 PRO D C   1 
ATOM 8899 O O   . PRO D 1 330 ? 116.107 153.847 111.418 1.00 62.96  ? 404 PRO D O   1 
ATOM 8900 C CB  . PRO D 1 330 ? 118.028 153.618 114.148 1.00 49.93  ? 404 PRO D CB  1 
ATOM 8901 C CG  . PRO D 1 330 ? 118.027 155.100 114.100 1.00 48.59  ? 404 PRO D CG  1 
ATOM 8902 C CD  . PRO D 1 330 ? 118.868 155.485 112.914 1.00 49.81  ? 404 PRO D CD  1 
ATOM 8903 N N   . LEU D 1 331 ? 116.078 151.851 112.471 1.00 60.67  ? 405 LEU D N   1 
ATOM 8904 C CA  . LEU D 1 331 ? 114.728 151.508 112.051 1.00 52.57  ? 405 LEU D CA  1 
ATOM 8905 C C   . LEU D 1 331 ? 113.787 151.635 113.237 1.00 61.02  ? 405 LEU D C   1 
ATOM 8906 O O   . LEU D 1 331 ? 113.853 150.805 114.157 1.00 67.98  ? 405 LEU D O   1 
ATOM 8907 C CB  . LEU D 1 331 ? 114.687 150.090 111.487 1.00 52.78  ? 405 LEU D CB  1 
ATOM 8908 C CG  . LEU D 1 331 ? 113.362 149.578 110.921 1.00 58.63  ? 405 LEU D CG  1 
ATOM 8909 C CD1 . LEU D 1 331 ? 113.612 148.770 109.661 1.00 59.86  ? 405 LEU D CD1 1 
ATOM 8910 C CD2 . LEU D 1 331 ? 112.624 148.733 111.944 1.00 59.56  ? 405 LEU D CD2 1 
ATOM 8911 N N   . PRO D 1 332 ? 112.910 152.638 113.275 1.00 56.26  ? 406 PRO D N   1 
ATOM 8912 C CA  . PRO D 1 332 ? 111.987 152.770 114.409 1.00 53.22  ? 406 PRO D CA  1 
ATOM 8913 C C   . PRO D 1 332 ? 110.765 151.879 114.232 1.00 56.44  ? 406 PRO D C   1 
ATOM 8914 O O   . PRO D 1 332 ? 110.064 151.956 113.221 1.00 58.44  ? 406 PRO D O   1 
ATOM 8915 C CB  . PRO D 1 332 ? 111.608 154.254 114.387 1.00 52.32  ? 406 PRO D CB  1 
ATOM 8916 C CG  . PRO D 1 332 ? 111.752 154.647 112.965 1.00 49.15  ? 406 PRO D CG  1 
ATOM 8917 C CD  . PRO D 1 332 ? 112.852 153.803 112.375 1.00 55.22  ? 406 PRO D CD  1 
ATOM 8918 N N   . SER D 1 333 ? 110.518 151.028 115.223 1.00 63.74  ? 407 SER D N   1 
ATOM 8919 C CA  . SER D 1 333 ? 109.349 150.160 115.252 1.00 65.16  ? 407 SER D CA  1 
ATOM 8920 C C   . SER D 1 333 ? 108.473 150.556 116.430 1.00 70.48  ? 407 SER D C   1 
ATOM 8921 O O   . SER D 1 333 ? 108.956 150.654 117.563 1.00 73.16  ? 407 SER D O   1 
ATOM 8922 C CB  . SER D 1 333 ? 109.750 148.688 115.357 1.00 69.22  ? 407 SER D CB  1 
ATOM 8923 O OG  . SER D 1 333 ? 108.609 147.849 115.356 1.00 66.34  ? 407 SER D OG  1 
ATOM 8924 N N   . ILE D 1 334 ? 107.192 150.778 116.161 1.00 72.91  ? 408 ILE D N   1 
ATOM 8925 C CA  . ILE D 1 334 ? 106.259 151.237 117.183 1.00 73.21  ? 408 ILE D CA  1 
ATOM 8926 C C   . ILE D 1 334 ? 105.877 150.064 118.075 1.00 74.44  ? 408 ILE D C   1 
ATOM 8927 O O   . ILE D 1 334 ? 105.667 148.945 117.593 1.00 79.76  ? 408 ILE D O   1 
ATOM 8928 C CB  . ILE D 1 334 ? 105.020 151.875 116.535 1.00 74.59  ? 408 ILE D CB  1 
ATOM 8929 C CG1 . ILE D 1 334 ? 105.438 153.017 115.611 1.00 77.01  ? 408 ILE D CG1 1 
ATOM 8930 C CG2 . ILE D 1 334 ? 104.062 152.385 117.593 1.00 76.20  ? 408 ILE D CG2 1 
ATOM 8931 C CD1 . ILE D 1 334 ? 104.277 153.743 114.976 1.00 75.58  ? 408 ILE D CD1 1 
ATOM 8932 N N   . CYS D 1 335 ? 105.791 150.316 119.377 1.00 75.80  ? 409 CYS D N   1 
ATOM 8933 C CA  . CYS D 1 335 ? 105.458 149.283 120.346 1.00 77.51  ? 409 CYS D CA  1 
ATOM 8934 C C   . CYS D 1 335 ? 103.999 149.389 120.768 1.00 78.37  ? 409 CYS D C   1 
ATOM 8935 O O   . CYS D 1 335 ? 103.452 150.484 120.918 1.00 81.20  ? 409 CYS D O   1 
ATOM 8936 C CB  . CYS D 1 335 ? 106.360 149.390 121.574 1.00 82.73  ? 409 CYS D CB  1 
ATOM 8937 S SG  . CYS D 1 335 ? 108.114 149.505 121.186 1.00 92.79  ? 409 CYS D SG  1 
ATOM 8938 N N   . VAL D 1 336 ? 103.370 148.228 120.959 1.00 82.62  ? 410 VAL D N   1 
ATOM 8939 C CA  . VAL D 1 336 ? 101.965 148.210 121.352 1.00 85.07  ? 410 VAL D CA  1 
ATOM 8940 C C   . VAL D 1 336 ? 101.793 148.718 122.780 1.00 89.42  ? 410 VAL D C   1 
ATOM 8941 O O   . VAL D 1 336 ? 100.870 149.489 123.068 1.00 91.54  ? 410 VAL D O   1 
ATOM 8942 C CB  . VAL D 1 336 ? 101.369 146.800 121.156 1.00 86.30  ? 410 VAL D CB  1 
ATOM 8943 C CG1 . VAL D 1 336 ? 102.056 145.773 122.046 1.00 87.02  ? 410 VAL D CG1 1 
ATOM 8944 C CG2 . VAL D 1 336 ? 99.871  146.817 121.418 1.00 86.90  ? 410 VAL D CG2 1 
ATOM 8945 N N   . ARG D 1 337 ? 102.671 148.305 123.696 1.00 89.36  ? 411 ARG D N   1 
ATOM 8946 C CA  . ARG D 1 337 ? 102.578 148.721 125.091 1.00 85.76  ? 411 ARG D CA  1 
ATOM 8947 C C   . ARG D 1 337 ? 103.773 149.560 125.522 1.00 87.41  ? 411 ARG D C   1 
ATOM 8948 O O   . ARG D 1 337 ? 103.591 150.702 125.958 1.00 91.11  ? 411 ARG D O   1 
ATOM 8949 C CB  . ARG D 1 337 ? 102.432 147.488 125.993 1.00 84.39  ? 411 ARG D CB  1 
ATOM 8950 C CG  . ARG D 1 337 ? 101.036 146.895 126.022 1.00 86.94  ? 411 ARG D CG  1 
ATOM 8951 C CD  . ARG D 1 337 ? 100.036 147.876 126.612 1.00 90.00  ? 411 ARG D CD  1 
ATOM 8952 N NE  . ARG D 1 337 ? 100.493 148.419 127.887 1.00 92.21  ? 411 ARG D NE  1 
ATOM 8953 C CZ  . ARG D 1 337 ? 100.321 147.824 129.060 1.00 92.35  ? 411 ARG D CZ  1 
ATOM 8954 N NH1 . ARG D 1 337 ? 99.700  146.660 129.161 1.00 90.90  ? 411 ARG D NH1 1 
ATOM 8955 N NH2 . ARG D 1 337 ? 100.783 148.413 130.159 1.00 91.84  ? 411 ARG D NH2 1 
ATOM 8956 N N   . ASP D 1 338 ? 104.988 149.035 125.404 1.00 88.14  ? 412 ASP D N   1 
ATOM 8957 C CA  . ASP D 1 338 ? 106.197 149.743 125.801 1.00 88.75  ? 412 ASP D CA  1 
ATOM 8958 C C   . ASP D 1 338 ? 107.388 149.021 125.190 1.00 88.87  ? 412 ASP D C   1 
ATOM 8959 O O   . ASP D 1 338 ? 107.268 147.858 124.787 1.00 89.26  ? 412 ASP D O   1 
ATOM 8960 C CB  . ASP D 1 338 ? 106.329 149.817 127.333 1.00 90.76  ? 412 ASP D CB  1 
ATOM 8961 C CG  . ASP D 1 338 ? 106.090 148.486 128.007 1.00 95.06  ? 412 ASP D CG  1 
ATOM 8962 O OD1 . ASP D 1 338 ? 105.135 147.786 127.617 1.00 98.20  ? 412 ASP D OD1 1 
ATOM 8963 O OD2 . ASP D 1 338 ? 106.857 148.138 128.929 1.00 92.37  ? 412 ASP D OD2 1 
ATOM 8964 N N   . PRO D 1 339 ? 108.546 149.680 125.100 1.00 84.77  ? 413 PRO D N   1 
ATOM 8965 C CA  . PRO D 1 339 ? 109.694 149.051 124.427 1.00 85.12  ? 413 PRO D CA  1 
ATOM 8966 C C   . PRO D 1 339 ? 110.164 147.757 125.064 1.00 84.65  ? 413 PRO D C   1 
ATOM 8967 O O   . PRO D 1 339 ? 110.830 146.964 124.387 1.00 82.50  ? 413 PRO D O   1 
ATOM 8968 C CB  . PRO D 1 339 ? 110.784 150.132 124.503 1.00 84.53  ? 413 PRO D CB  1 
ATOM 8969 C CG  . PRO D 1 339 ? 110.280 151.148 125.478 1.00 84.45  ? 413 PRO D CG  1 
ATOM 8970 C CD  . PRO D 1 339 ? 108.799 151.103 125.369 1.00 85.43  ? 413 PRO D CD  1 
ATOM 8971 N N   . VAL D 1 340 ? 109.851 147.511 126.330 1.00 91.33  ? 414 VAL D N   1 
ATOM 8972 C CA  . VAL D 1 340 ? 110.417 146.384 127.063 1.00 94.02  ? 414 VAL D CA  1 
ATOM 8973 C C   . VAL D 1 340 ? 109.453 145.207 127.135 1.00 96.25  ? 414 VAL D C   1 
ATOM 8974 O O   . VAL D 1 340 ? 109.817 144.080 126.800 1.00 94.87  ? 414 VAL D O   1 
ATOM 8975 C CB  . VAL D 1 340 ? 110.853 146.833 128.473 1.00 91.84  ? 414 VAL D CB  1 
ATOM 8976 C CG1 . VAL D 1 340 ? 111.415 145.657 129.228 1.00 89.58  ? 414 VAL D CG1 1 
ATOM 8977 C CG2 . VAL D 1 340 ? 111.876 147.949 128.378 1.00 90.89  ? 414 VAL D CG2 1 
ATOM 8978 N N   . SER D 1 341 ? 108.216 145.447 127.580 1.00 96.08  ? 415 SER D N   1 
ATOM 8979 C CA  . SER D 1 341 ? 107.299 144.340 127.838 1.00 93.34  ? 415 SER D CA  1 
ATOM 8980 C C   . SER D 1 341 ? 106.953 143.594 126.558 1.00 91.10  ? 415 SER D C   1 
ATOM 8981 O O   . SER D 1 341 ? 106.747 142.374 126.578 1.00 92.78  ? 415 SER D O   1 
ATOM 8982 C CB  . SER D 1 341 ? 106.029 144.850 128.516 1.00 95.60  ? 415 SER D CB  1 
ATOM 8983 O OG  . SER D 1 341 ? 105.236 145.598 127.613 1.00 99.35  ? 415 SER D OG  1 
ATOM 8984 N N   . ASP D 1 342 ? 106.875 144.310 125.434 1.00 88.21  ? 416 ASP D N   1 
ATOM 8985 C CA  . ASP D 1 342 ? 106.573 143.652 124.168 1.00 92.93  ? 416 ASP D CA  1 
ATOM 8986 C C   . ASP D 1 342 ? 107.663 142.657 123.795 1.00 92.12  ? 416 ASP D C   1 
ATOM 8987 O O   . ASP D 1 342 ? 107.376 141.583 123.256 1.00 90.71  ? 416 ASP D O   1 
ATOM 8988 C CB  . ASP D 1 342 ? 106.384 144.690 123.060 1.00 91.81  ? 416 ASP D CB  1 
ATOM 8989 C CG  . ASP D 1 342 ? 107.607 145.567 122.859 1.00 94.12  ? 416 ASP D CG  1 
ATOM 8990 O OD1 . ASP D 1 342 ? 108.590 145.418 123.615 1.00 95.67  ? 416 ASP D OD1 1 
ATOM 8991 O OD2 . ASP D 1 342 ? 107.587 146.405 121.933 1.00 95.15  ? 416 ASP D OD2 1 
ATOM 8992 N N   . TRP D 1 343 ? 108.923 142.996 124.081 1.00 80.69  ? 417 TRP D N   1 
ATOM 8993 C CA  . TRP D 1 343 ? 110.019 142.082 123.779 1.00 77.43  ? 417 TRP D CA  1 
ATOM 8994 C C   . TRP D 1 343 ? 109.901 140.794 124.580 1.00 78.02  ? 417 TRP D C   1 
ATOM 8995 O O   . TRP D 1 343 ? 110.105 139.699 124.044 1.00 80.10  ? 417 TRP D O   1 
ATOM 8996 C CB  . TRP D 1 343 ? 111.359 142.763 124.050 1.00 75.26  ? 417 TRP D CB  1 
ATOM 8997 C CG  . TRP D 1 343 ? 112.533 141.910 123.697 1.00 75.87  ? 417 TRP D CG  1 
ATOM 8998 C CD1 . TRP D 1 343 ? 112.900 141.504 122.452 1.00 75.68  ? 417 TRP D CD1 1 
ATOM 8999 C CD2 . TRP D 1 343 ? 113.508 141.376 124.598 1.00 77.24  ? 417 TRP D CD2 1 
ATOM 9000 N NE1 . TRP D 1 343 ? 114.035 140.738 122.520 1.00 75.23  ? 417 TRP D NE1 1 
ATOM 9001 C CE2 . TRP D 1 343 ? 114.430 140.647 123.827 1.00 75.88  ? 417 TRP D CE2 1 
ATOM 9002 C CE3 . TRP D 1 343 ? 113.689 141.441 125.981 1.00 76.56  ? 417 TRP D CE3 1 
ATOM 9003 C CZ2 . TRP D 1 343 ? 115.516 139.987 124.392 1.00 73.78  ? 417 TRP D CZ2 1 
ATOM 9004 C CZ3 . TRP D 1 343 ? 114.766 140.785 126.539 1.00 73.06  ? 417 TRP D CZ3 1 
ATOM 9005 C CH2 . TRP D 1 343 ? 115.666 140.069 125.746 1.00 70.76  ? 417 TRP D CH2 1 
ATOM 9006 N N   . PHE D 1 344 ? 109.558 140.900 125.864 1.00 89.29  ? 418 PHE D N   1 
ATOM 9007 C CA  . PHE D 1 344 ? 109.433 139.700 126.681 1.00 89.36  ? 418 PHE D CA  1 
ATOM 9008 C C   . PHE D 1 344 ? 108.202 138.889 126.303 1.00 90.19  ? 418 PHE D C   1 
ATOM 9009 O O   . PHE D 1 344 ? 108.240 137.656 126.344 1.00 90.46  ? 418 PHE D O   1 
ATOM 9010 C CB  . PHE D 1 344 ? 109.406 140.077 128.159 1.00 88.49  ? 418 PHE D CB  1 
ATOM 9011 C CG  . PHE D 1 344 ? 110.762 140.381 128.721 1.00 90.14  ? 418 PHE D CG  1 
ATOM 9012 C CD1 . PHE D 1 344 ? 111.605 139.360 129.118 1.00 90.29  ? 418 PHE D CD1 1 
ATOM 9013 C CD2 . PHE D 1 344 ? 111.201 141.688 128.837 1.00 90.97  ? 418 PHE D CD2 1 
ATOM 9014 C CE1 . PHE D 1 344 ? 112.857 139.635 129.628 1.00 90.75  ? 418 PHE D CE1 1 
ATOM 9015 C CE2 . PHE D 1 344 ? 112.452 141.970 129.347 1.00 91.08  ? 418 PHE D CE2 1 
ATOM 9016 C CZ  . PHE D 1 344 ? 113.280 140.943 129.743 1.00 89.99  ? 418 PHE D CZ  1 
ATOM 9017 N N   . GLU D 1 345 ? 107.110 139.555 125.923 1.00 88.60  ? 419 GLU D N   1 
ATOM 9018 C CA  . GLU D 1 345 ? 105.945 138.831 125.422 1.00 82.91  ? 419 GLU D CA  1 
ATOM 9019 C C   . GLU D 1 345 ? 106.279 138.080 124.139 1.00 83.49  ? 419 GLU D C   1 
ATOM 9020 O O   . GLU D 1 345 ? 105.843 136.937 123.939 1.00 87.26  ? 419 GLU D O   1 
ATOM 9021 C CB  . GLU D 1 345 ? 104.789 139.804 125.196 1.00 83.20  ? 419 GLU D CB  1 
ATOM 9022 C CG  . GLU D 1 345 ? 103.564 139.187 124.552 1.00 88.26  ? 419 GLU D CG  1 
ATOM 9023 C CD  . GLU D 1 345 ? 102.736 140.204 123.791 1.00 89.87  ? 419 GLU D CD  1 
ATOM 9024 O OE1 . GLU D 1 345 ? 103.209 141.346 123.617 1.00 88.32  ? 419 GLU D OE1 1 
ATOM 9025 O OE2 . GLU D 1 345 ? 101.612 139.860 123.368 1.00 91.47  ? 419 GLU D OE2 1 
ATOM 9026 N N   . SER D 1 346 ? 107.046 138.713 123.250 1.00 85.76  ? 420 SER D N   1 
ATOM 9027 C CA  . SER D 1 346 ? 107.469 138.039 122.031 1.00 88.23  ? 420 SER D CA  1 
ATOM 9028 C C   . SER D 1 346 ? 108.376 136.860 122.348 1.00 91.45  ? 420 SER D C   1 
ATOM 9029 O O   . SER D 1 346 ? 108.277 135.805 121.715 1.00 94.20  ? 420 SER D O   1 
ATOM 9030 C CB  . SER D 1 346 ? 108.172 139.022 121.102 1.00 90.92  ? 420 SER D CB  1 
ATOM 9031 O OG  . SER D 1 346 ? 108.535 138.378 119.897 1.00 95.22  ? 420 SER D OG  1 
ATOM 9032 N N   . LEU D 1 347 ? 109.266 137.017 123.327 1.00 85.91  ? 421 LEU D N   1 
ATOM 9033 C CA  . LEU D 1 347 ? 110.098 135.895 123.747 1.00 83.95  ? 421 LEU D CA  1 
ATOM 9034 C C   . LEU D 1 347 ? 109.246 134.757 124.294 1.00 84.75  ? 421 LEU D C   1 
ATOM 9035 O O   . LEU D 1 347 ? 109.539 133.580 124.057 1.00 86.66  ? 421 LEU D O   1 
ATOM 9036 C CB  . LEU D 1 347 ? 111.110 136.355 124.792 1.00 84.09  ? 421 LEU D CB  1 
ATOM 9037 C CG  . LEU D 1 347 ? 112.350 137.066 124.260 1.00 82.87  ? 421 LEU D CG  1 
ATOM 9038 C CD1 . LEU D 1 347 ? 113.255 137.470 125.408 1.00 83.77  ? 421 LEU D CD1 1 
ATOM 9039 C CD2 . LEU D 1 347 ? 113.087 136.183 123.272 1.00 85.32  ? 421 LEU D CD2 1 
ATOM 9040 N N   . ALA D 1 348 ? 108.186 135.092 125.028 1.00 90.94  ? 422 ALA D N   1 
ATOM 9041 C CA  . ALA D 1 348 ? 107.336 134.073 125.634 1.00 92.68  ? 422 ALA D CA  1 
ATOM 9042 C C   . ALA D 1 348 ? 106.574 133.284 124.576 1.00 93.95  ? 422 ALA D C   1 
ATOM 9043 O O   . ALA D 1 348 ? 106.703 132.058 124.486 1.00 94.87  ? 422 ALA D O   1 
ATOM 9044 C CB  . ALA D 1 348 ? 106.369 134.722 126.625 1.00 92.00  ? 422 ALA D CB  1 
ATOM 9045 N N   . GLN D 1 349 ? 105.763 133.966 123.765 1.00 102.03 ? 423 GLN D N   1 
ATOM 9046 C CA  . GLN D 1 349 ? 104.926 133.230 122.817 1.00 103.07 ? 423 GLN D CA  1 
ATOM 9047 C C   . GLN D 1 349 ? 105.665 132.881 121.528 1.00 103.46 ? 423 GLN D C   1 
ATOM 9048 O O   . GLN D 1 349 ? 105.607 131.736 121.067 1.00 103.53 ? 423 GLN D O   1 
ATOM 9049 C CB  . GLN D 1 349 ? 103.636 133.998 122.513 1.00 103.37 ? 423 GLN D CB  1 
ATOM 9050 C CG  . GLN D 1 349 ? 102.600 133.954 123.637 1.00 104.36 ? 423 GLN D CG  1 
ATOM 9051 C CD  . GLN D 1 349 ? 102.790 135.023 124.688 1.00 104.41 ? 423 GLN D CD  1 
ATOM 9052 O OE1 . GLN D 1 349 ? 103.451 136.027 124.454 1.00 103.93 ? 423 GLN D OE1 1 
ATOM 9053 N NE2 . GLN D 1 349 ? 102.206 134.808 125.861 1.00 103.19 ? 423 GLN D NE2 1 
ATOM 9054 N N   . CYS D 1 350 ? 106.354 133.850 120.924 1.00 103.83 ? 424 CYS D N   1 
ATOM 9055 C CA  . CYS D 1 350 ? 107.001 133.609 119.637 1.00 105.23 ? 424 CYS D CA  1 
ATOM 9056 C C   . CYS D 1 350 ? 108.101 132.557 119.736 1.00 105.36 ? 424 CYS D C   1 
ATOM 9057 O O   . CYS D 1 350 ? 108.230 131.703 118.852 1.00 104.95 ? 424 CYS D O   1 
ATOM 9058 C CB  . CYS D 1 350 ? 107.572 134.917 119.089 1.00 103.13 ? 424 CYS D CB  1 
ATOM 9059 S SG  . CYS D 1 350 ? 108.423 134.746 117.503 1.00 103.21 ? 424 CYS D SG  1 
ATOM 9060 N N   . LEU D 1 351 ? 108.906 132.602 120.798 1.00 103.09 ? 425 LEU D N   1 
ATOM 9061 C CA  . LEU D 1 351 ? 110.115 131.794 120.876 1.00 101.07 ? 425 LEU D CA  1 
ATOM 9062 C C   . LEU D 1 351 ? 110.118 130.802 122.032 1.00 101.67 ? 425 LEU D C   1 
ATOM 9063 O O   . LEU D 1 351 ? 110.994 129.931 122.073 1.00 102.35 ? 425 LEU D O   1 
ATOM 9064 C CB  . LEU D 1 351 ? 111.344 132.713 120.983 1.00 101.43 ? 425 LEU D CB  1 
ATOM 9065 C CG  . LEU D 1 351 ? 112.753 132.121 120.937 1.00 102.83 ? 425 LEU D CG  1 
ATOM 9066 C CD1 . LEU D 1 351 ? 112.984 131.455 119.593 1.00 100.54 ? 425 LEU D CD1 1 
ATOM 9067 C CD2 . LEU D 1 351 ? 113.799 133.193 121.193 1.00 101.44 ? 425 LEU D CD2 1 
ATOM 9068 N N   . HIS D 1 352 ? 109.154 130.891 122.951 1.00 106.69 ? 426 HIS D N   1 
ATOM 9069 C CA  . HIS D 1 352 ? 109.104 130.048 124.148 1.00 105.49 ? 426 HIS D CA  1 
ATOM 9070 C C   . HIS D 1 352 ? 110.363 130.234 124.997 1.00 105.33 ? 426 HIS D C   1 
ATOM 9071 O O   . HIS D 1 352 ? 111.162 129.317 125.194 1.00 106.75 ? 426 HIS D O   1 
ATOM 9072 C CB  . HIS D 1 352 ? 108.887 128.575 123.782 1.00 106.39 ? 426 HIS D CB  1 
ATOM 9073 C CG  . HIS D 1 352 ? 107.638 128.324 122.997 1.00 106.98 ? 426 HIS D CG  1 
ATOM 9074 N ND1 . HIS D 1 352 ? 107.385 127.126 122.365 1.00 107.22 ? 426 HIS D ND1 1 
ATOM 9075 C CD2 . HIS D 1 352 ? 106.570 129.116 122.741 1.00 105.85 ? 426 HIS D CD2 1 
ATOM 9076 C CE1 . HIS D 1 352 ? 106.216 127.190 121.753 1.00 105.41 ? 426 HIS D CE1 1 
ATOM 9077 N NE2 . HIS D 1 352 ? 105.701 128.388 121.965 1.00 104.43 ? 426 HIS D NE2 1 
ATOM 9078 N N   . TRP D 1 353 ? 110.523 131.460 125.499 1.00 103.09 ? 427 TRP D N   1 
ATOM 9079 C CA  . TRP D 1 353 ? 111.683 131.792 126.318 1.00 104.63 ? 427 TRP D CA  1 
ATOM 9080 C C   . TRP D 1 353 ? 111.661 131.061 127.655 1.00 104.17 ? 427 TRP D C   1 
ATOM 9081 O O   . TRP D 1 353 ? 112.708 130.911 128.294 1.00 103.02 ? 427 TRP D O   1 
ATOM 9082 C CB  . TRP D 1 353 ? 111.746 133.305 126.531 1.00 105.69 ? 427 TRP D CB  1 
ATOM 9083 C CG  . TRP D 1 353 ? 112.785 133.759 127.508 1.00 105.69 ? 427 TRP D CG  1 
ATOM 9084 C CD1 . TRP D 1 353 ? 114.103 133.413 127.523 1.00 103.79 ? 427 TRP D CD1 1 
ATOM 9085 C CD2 . TRP D 1 353 ? 112.594 134.653 128.610 1.00 103.73 ? 427 TRP D CD2 1 
ATOM 9086 N NE1 . TRP D 1 353 ? 114.744 134.032 128.567 1.00 102.14 ? 427 TRP D NE1 1 
ATOM 9087 C CE2 . TRP D 1 353 ? 113.839 134.799 129.251 1.00 102.37 ? 427 TRP D CE2 1 
ATOM 9088 C CE3 . TRP D 1 353 ? 111.489 135.343 129.118 1.00 102.75 ? 427 TRP D CE3 1 
ATOM 9089 C CZ2 . TRP D 1 353 ? 114.011 135.606 130.372 1.00 102.84 ? 427 TRP D CZ2 1 
ATOM 9090 C CZ3 . TRP D 1 353 ? 111.662 136.142 130.232 1.00 103.51 ? 427 TRP D CZ3 1 
ATOM 9091 C CH2 . TRP D 1 353 ? 112.914 136.269 130.845 1.00 102.91 ? 427 TRP D CH2 1 
ATOM 9092 N N   . ASN D 1 354 ? 110.493 130.601 128.091 1.00 113.01 ? 428 ASN D N   1 
ATOM 9093 C CA  . ASN D 1 354 ? 110.385 129.839 129.329 1.00 112.47 ? 428 ASN D CA  1 
ATOM 9094 C C   . ASN D 1 354 ? 109.071 129.067 129.380 1.00 112.51 ? 428 ASN D C   1 
ATOM 9095 O O   . ASN D 1 354 ? 109.055 127.841 129.270 1.00 113.55 ? 428 ASN D O   1 
ATOM 9096 C CB  . ASN D 1 354 ? 110.501 130.760 130.544 1.00 113.47 ? 428 ASN D CB  1 
ATOM 9097 C CG  . ASN D 1 354 ? 110.628 129.994 131.845 1.00 116.13 ? 428 ASN D CG  1 
ATOM 9098 O OD1 . ASN D 1 354 ? 109.635 129.724 132.520 1.00 115.77 ? 428 ASN D OD1 1 
ATOM 9099 N ND2 . ASN D 1 354 ? 111.856 129.637 132.203 1.00 114.62 ? 428 ASN D ND2 1 
# 
