data_9CPV
# 
_entry.id   9CPV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CPV         pdb_00009cpv 10.2210/pdb9cpv/pdb 
WWPDB D_1000285997 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CPV 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wilson@scripps.edu 
_pdbx_contact_author.name_first         Ian 
_pdbx_contact_author.name_last          Wilson 
_pdbx_contact_author.name_mi            A. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6469-2419 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Feng, Z.'     1 ? 
'Wilson, I.A.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structures of CR3022-like antibodies' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Feng, Z.'     1 ? 
primary 'Wilson, I.A.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man 'C03-0614 Fab heavy chain' 23420.504 1 ? ? ?                                                ? 
2 polymer  man 'C03-0614 Fab light chain' 24289.885 1 ? ? ?                                                ? 
3 polymer  man 'CC12.3 Fab heavy chain' 23377.150 1 ? ? ?                                                ? 
4 polymer  man 'CC12.3 Fab light chain' 23344.883 1 ? ? ?                                                ? 
5 polymer  man 'Spike protein S1' 23104.867 1 ? ? 'Receptor binding domain (UNP residues 333-530)' ? 
6 branched man 
'beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 586.542   1 ? 
? ?                                                ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVQLVQSGTEVKKPGESLKISCKGSGKSLIMYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSINTAY
LQWSSLKASDTAMYYCAGGSGIFTPMDVWGQGTAVAVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW
NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
;EVQLVQSGTEVKKPGESLKISCKGSGKSLIMYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSINTAY
LQWSSLKASDTAMYYCAGGSGIFTPMDVWGQGTAVAVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW
NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
H ? 
2 'polypeptide(L)' no no 
;DIQLTQSPDSLAVSLGERATINCKSSQSVLYSSINKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLT
ISSLQAEDVAVYYCQQYYSTPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;DIQLTQSPDSLAVSLGERATINCKSSQSVLYSSINKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLT
ISSLQAEDVAVYYCQQYYSTPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
3 'polypeptide(L)' no no 
;QVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTFYADSVKGRFTISRDNSKSTLYL
QMNSLRVEDTAVYYCARDFGDFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
;QVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTFYADSVKGRFTISRDNSKSTLYL
QMNSLRVEDTAVYYCARDFGDFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
C ? 
4 'polypeptide(L)' no no 
;EIVLTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEP
EDFAVYYCQQYGSSPRTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;EIVLTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEP
EDFAVYYCQQYGSSPRTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
D ? 
5 'polypeptide(L)' no no 
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSGHHHHHH
;
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSGHHHHHH
;
A ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLN n 
1 7   SER n 
1 8   GLY n 
1 9   THR n 
1 10  GLU n 
1 11  VAL n 
1 12  LYS n 
1 13  LYS n 
1 14  PRO n 
1 15  GLY n 
1 16  GLU n 
1 17  SER n 
1 18  LEU n 
1 19  LYS n 
1 20  ILE n 
1 21  SER n 
1 22  CYS n 
1 23  LYS n 
1 24  GLY n 
1 25  SER n 
1 26  GLY n 
1 27  LYS n 
1 28  SER n 
1 29  LEU n 
1 30  ILE n 
1 31  MET n 
1 32  TYR n 
1 33  TRP n 
1 34  ILE n 
1 35  GLY n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  MET n 
1 41  PRO n 
1 42  GLY n 
1 43  LYS n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  MET n 
1 49  GLY n 
1 50  ILE n 
1 51  ILE n 
1 52  TYR n 
1 53  PRO n 
1 54  GLY n 
1 55  ASP n 
1 56  SER n 
1 57  ASP n 
1 58  THR n 
1 59  ARG n 
1 60  TYR n 
1 61  SER n 
1 62  PRO n 
1 63  SER n 
1 64  PHE n 
1 65  GLN n 
1 66  GLY n 
1 67  GLN n 
1 68  VAL n 
1 69  THR n 
1 70  ILE n 
1 71  SER n 
1 72  ALA n 
1 73  ASP n 
1 74  LYS n 
1 75  SER n 
1 76  ILE n 
1 77  ASN n 
1 78  THR n 
1 79  ALA n 
1 80  TYR n 
1 81  LEU n 
1 82  GLN n 
1 83  TRP n 
1 84  SER n 
1 85  SER n 
1 86  LEU n 
1 87  LYS n 
1 88  ALA n 
1 89  SER n 
1 90  ASP n 
1 91  THR n 
1 92  ALA n 
1 93  MET n 
1 94  TYR n 
1 95  TYR n 
1 96  CYS n 
1 97  ALA n 
1 98  GLY n 
1 99  GLY n 
1 100 SER n 
1 101 GLY n 
1 102 ILE n 
1 103 PHE n 
1 104 THR n 
1 105 PRO n 
1 106 MET n 
1 107 ASP n 
1 108 VAL n 
1 109 TRP n 
1 110 GLY n 
1 111 GLN n 
1 112 GLY n 
1 113 THR n 
1 114 ALA n 
1 115 VAL n 
1 116 ALA n 
1 117 VAL n 
1 118 SER n 
1 119 SER n 
1 120 ALA n 
1 121 SER n 
1 122 THR n 
1 123 LYS n 
1 124 GLY n 
1 125 PRO n 
1 126 SER n 
1 127 VAL n 
1 128 PHE n 
1 129 PRO n 
1 130 LEU n 
1 131 ALA n 
1 132 PRO n 
1 133 SER n 
1 134 SER n 
1 135 LYS n 
1 136 SER n 
1 137 THR n 
1 138 SER n 
1 139 GLY n 
1 140 GLY n 
1 141 THR n 
1 142 ALA n 
1 143 ALA n 
1 144 LEU n 
1 145 GLY n 
1 146 CYS n 
1 147 LEU n 
1 148 VAL n 
1 149 LYS n 
1 150 ASP n 
1 151 TYR n 
1 152 PHE n 
1 153 PRO n 
1 154 GLU n 
1 155 PRO n 
1 156 VAL n 
1 157 THR n 
1 158 VAL n 
1 159 SER n 
1 160 TRP n 
1 161 ASN n 
1 162 SER n 
1 163 GLY n 
1 164 ALA n 
1 165 LEU n 
1 166 THR n 
1 167 SER n 
1 168 GLY n 
1 169 VAL n 
1 170 HIS n 
1 171 THR n 
1 172 PHE n 
1 173 PRO n 
1 174 ALA n 
1 175 VAL n 
1 176 LEU n 
1 177 GLN n 
1 178 SER n 
1 179 SER n 
1 180 GLY n 
1 181 LEU n 
1 182 TYR n 
1 183 SER n 
1 184 LEU n 
1 185 SER n 
1 186 SER n 
1 187 VAL n 
1 188 VAL n 
1 189 THR n 
1 190 VAL n 
1 191 PRO n 
1 192 SER n 
1 193 SER n 
1 194 SER n 
1 195 LEU n 
1 196 GLY n 
1 197 THR n 
1 198 GLN n 
1 199 THR n 
1 200 TYR n 
1 201 ILE n 
1 202 CYS n 
1 203 ASN n 
1 204 VAL n 
1 205 ASN n 
1 206 HIS n 
1 207 LYS n 
1 208 PRO n 
1 209 SER n 
1 210 ASN n 
1 211 THR n 
1 212 LYS n 
1 213 VAL n 
1 214 ASP n 
1 215 LYS n 
1 216 LYS n 
1 217 VAL n 
1 218 GLU n 
1 219 PRO n 
1 220 LYS n 
1 221 SER n 
1 222 CYS n 
2 1   ASP n 
2 2   ILE n 
2 3   GLN n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   ASP n 
2 10  SER n 
2 11  LEU n 
2 12  ALA n 
2 13  VAL n 
2 14  SER n 
2 15  LEU n 
2 16  GLY n 
2 17  GLU n 
2 18  ARG n 
2 19  ALA n 
2 20  THR n 
2 21  ILE n 
2 22  ASN n 
2 23  CYS n 
2 24  LYS n 
2 25  SER n 
2 26  SER n 
2 27  GLN n 
2 28  SER n 
2 29  VAL n 
2 30  LEU n 
2 31  TYR n 
2 32  SER n 
2 33  SER n 
2 34  ILE n 
2 35  ASN n 
2 36  LYS n 
2 37  ASN n 
2 38  TYR n 
2 39  LEU n 
2 40  ALA n 
2 41  TRP n 
2 42  TYR n 
2 43  GLN n 
2 44  GLN n 
2 45  LYS n 
2 46  PRO n 
2 47  GLY n 
2 48  GLN n 
2 49  PRO n 
2 50  PRO n 
2 51  LYS n 
2 52  LEU n 
2 53  LEU n 
2 54  ILE n 
2 55  TYR n 
2 56  TRP n 
2 57  ALA n 
2 58  SER n 
2 59  THR n 
2 60  ARG n 
2 61  GLU n 
2 62  SER n 
2 63  GLY n 
2 64  VAL n 
2 65  PRO n 
2 66  ASP n 
2 67  ARG n 
2 68  PHE n 
2 69  SER n 
2 70  GLY n 
2 71  SER n 
2 72  GLY n 
2 73  SER n 
2 74  GLY n 
2 75  THR n 
2 76  ASP n 
2 77  PHE n 
2 78  THR n 
2 79  LEU n 
2 80  THR n 
2 81  ILE n 
2 82  SER n 
2 83  SER n 
2 84  LEU n 
2 85  GLN n 
2 86  ALA n 
2 87  GLU n 
2 88  ASP n 
2 89  VAL n 
2 90  ALA n 
2 91  VAL n 
2 92  TYR n 
2 93  TYR n 
2 94  CYS n 
2 95  GLN n 
2 96  GLN n 
2 97  TYR n 
2 98  TYR n 
2 99  SER n 
2 100 THR n 
2 101 PRO n 
2 102 TYR n 
2 103 THR n 
2 104 PHE n 
2 105 GLY n 
2 106 GLN n 
2 107 GLY n 
2 108 THR n 
2 109 LYS n 
2 110 VAL n 
2 111 GLU n 
2 112 ILE n 
2 113 LYS n 
2 114 ARG n 
2 115 THR n 
2 116 VAL n 
2 117 ALA n 
2 118 ALA n 
2 119 PRO n 
2 120 SER n 
2 121 VAL n 
2 122 PHE n 
2 123 ILE n 
2 124 PHE n 
2 125 PRO n 
2 126 PRO n 
2 127 SER n 
2 128 ASP n 
2 129 GLU n 
2 130 GLN n 
2 131 LEU n 
2 132 LYS n 
2 133 SER n 
2 134 GLY n 
2 135 THR n 
2 136 ALA n 
2 137 SER n 
2 138 VAL n 
2 139 VAL n 
2 140 CYS n 
2 141 LEU n 
2 142 LEU n 
2 143 ASN n 
2 144 ASN n 
2 145 PHE n 
2 146 TYR n 
2 147 PRO n 
2 148 ARG n 
2 149 GLU n 
2 150 ALA n 
2 151 LYS n 
2 152 VAL n 
2 153 GLN n 
2 154 TRP n 
2 155 LYS n 
2 156 VAL n 
2 157 ASP n 
2 158 ASN n 
2 159 ALA n 
2 160 LEU n 
2 161 GLN n 
2 162 SER n 
2 163 GLY n 
2 164 ASN n 
2 165 SER n 
2 166 GLN n 
2 167 GLU n 
2 168 SER n 
2 169 VAL n 
2 170 THR n 
2 171 GLU n 
2 172 GLN n 
2 173 ASP n 
2 174 SER n 
2 175 LYS n 
2 176 ASP n 
2 177 SER n 
2 178 THR n 
2 179 TYR n 
2 180 SER n 
2 181 LEU n 
2 182 SER n 
2 183 SER n 
2 184 THR n 
2 185 LEU n 
2 186 THR n 
2 187 LEU n 
2 188 SER n 
2 189 LYS n 
2 190 ALA n 
2 191 ASP n 
2 192 TYR n 
2 193 GLU n 
2 194 LYS n 
2 195 HIS n 
2 196 LYS n 
2 197 VAL n 
2 198 TYR n 
2 199 ALA n 
2 200 CYS n 
2 201 GLU n 
2 202 VAL n 
2 203 THR n 
2 204 HIS n 
2 205 GLN n 
2 206 GLY n 
2 207 LEU n 
2 208 SER n 
2 209 SER n 
2 210 PRO n 
2 211 VAL n 
2 212 THR n 
2 213 LYS n 
2 214 SER n 
2 215 PHE n 
2 216 ASN n 
2 217 ARG n 
2 218 GLY n 
2 219 GLU n 
2 220 CYS n 
3 1   GLN n 
3 2   VAL n 
3 3   GLN n 
3 4   LEU n 
3 5   VAL n 
3 6   GLU n 
3 7   SER n 
3 8   GLY n 
3 9   GLY n 
3 10  GLY n 
3 11  LEU n 
3 12  ILE n 
3 13  GLN n 
3 14  PRO n 
3 15  GLY n 
3 16  GLY n 
3 17  SER n 
3 18  LEU n 
3 19  ARG n 
3 20  LEU n 
3 21  SER n 
3 22  CYS n 
3 23  ALA n 
3 24  ALA n 
3 25  SER n 
3 26  GLY n 
3 27  PHE n 
3 28  THR n 
3 29  VAL n 
3 30  SER n 
3 31  SER n 
3 32  ASN n 
3 33  TYR n 
3 34  MET n 
3 35  SER n 
3 36  TRP n 
3 37  VAL n 
3 38  ARG n 
3 39  GLN n 
3 40  ALA n 
3 41  PRO n 
3 42  GLY n 
3 43  LYS n 
3 44  GLY n 
3 45  LEU n 
3 46  GLU n 
3 47  TRP n 
3 48  VAL n 
3 49  SER n 
3 50  VAL n 
3 51  ILE n 
3 52  TYR n 
3 53  SER n 
3 54  GLY n 
3 55  GLY n 
3 56  SER n 
3 57  THR n 
3 58  PHE n 
3 59  TYR n 
3 60  ALA n 
3 61  ASP n 
3 62  SER n 
3 63  VAL n 
3 64  LYS n 
3 65  GLY n 
3 66  ARG n 
3 67  PHE n 
3 68  THR n 
3 69  ILE n 
3 70  SER n 
3 71  ARG n 
3 72  ASP n 
3 73  ASN n 
3 74  SER n 
3 75  LYS n 
3 76  SER n 
3 77  THR n 
3 78  LEU n 
3 79  TYR n 
3 80  LEU n 
3 81  GLN n 
3 82  MET n 
3 83  ASN n 
3 84  SER n 
3 85  LEU n 
3 86  ARG n 
3 87  VAL n 
3 88  GLU n 
3 89  ASP n 
3 90  THR n 
3 91  ALA n 
3 92  VAL n 
3 93  TYR n 
3 94  TYR n 
3 95  CYS n 
3 96  ALA n 
3 97  ARG n 
3 98  ASP n 
3 99  PHE n 
3 100 GLY n 
3 101 ASP n 
3 102 PHE n 
3 103 TYR n 
3 104 PHE n 
3 105 ASP n 
3 106 TYR n 
3 107 TRP n 
3 108 GLY n 
3 109 GLN n 
3 110 GLY n 
3 111 THR n 
3 112 LEU n 
3 113 VAL n 
3 114 THR n 
3 115 VAL n 
3 116 SER n 
3 117 SER n 
3 118 ALA n 
3 119 SER n 
3 120 THR n 
3 121 LYS n 
3 122 GLY n 
3 123 PRO n 
3 124 SER n 
3 125 VAL n 
3 126 PHE n 
3 127 PRO n 
3 128 LEU n 
3 129 ALA n 
3 130 PRO n 
3 131 SER n 
3 132 SER n 
3 133 LYS n 
3 134 SER n 
3 135 THR n 
3 136 SER n 
3 137 GLY n 
3 138 GLY n 
3 139 THR n 
3 140 ALA n 
3 141 ALA n 
3 142 LEU n 
3 143 GLY n 
3 144 CYS n 
3 145 LEU n 
3 146 VAL n 
3 147 LYS n 
3 148 ASP n 
3 149 TYR n 
3 150 PHE n 
3 151 PRO n 
3 152 GLU n 
3 153 PRO n 
3 154 VAL n 
3 155 THR n 
3 156 VAL n 
3 157 SER n 
3 158 TRP n 
3 159 ASN n 
3 160 SER n 
3 161 GLY n 
3 162 ALA n 
3 163 LEU n 
3 164 THR n 
3 165 SER n 
3 166 GLY n 
3 167 VAL n 
3 168 HIS n 
3 169 THR n 
3 170 PHE n 
3 171 PRO n 
3 172 ALA n 
3 173 VAL n 
3 174 LEU n 
3 175 GLN n 
3 176 SER n 
3 177 SER n 
3 178 GLY n 
3 179 LEU n 
3 180 TYR n 
3 181 SER n 
3 182 LEU n 
3 183 SER n 
3 184 SER n 
3 185 VAL n 
3 186 VAL n 
3 187 THR n 
3 188 VAL n 
3 189 PRO n 
3 190 SER n 
3 191 SER n 
3 192 SER n 
3 193 LEU n 
3 194 GLY n 
3 195 THR n 
3 196 GLN n 
3 197 THR n 
3 198 TYR n 
3 199 ILE n 
3 200 CYS n 
3 201 ASN n 
3 202 VAL n 
3 203 ASN n 
3 204 HIS n 
3 205 LYS n 
3 206 PRO n 
3 207 SER n 
3 208 ASN n 
3 209 THR n 
3 210 LYS n 
3 211 VAL n 
3 212 ASP n 
3 213 LYS n 
3 214 LYS n 
3 215 VAL n 
3 216 GLU n 
3 217 PRO n 
3 218 LYS n 
3 219 SER n 
3 220 CYS n 
4 1   GLU n 
4 2   ILE n 
4 3   VAL n 
4 4   LEU n 
4 5   THR n 
4 6   GLN n 
4 7   SER n 
4 8   PRO n 
4 9   GLY n 
4 10  THR n 
4 11  LEU n 
4 12  SER n 
4 13  LEU n 
4 14  SER n 
4 15  PRO n 
4 16  GLY n 
4 17  GLU n 
4 18  ARG n 
4 19  ALA n 
4 20  THR n 
4 21  LEU n 
4 22  SER n 
4 23  CYS n 
4 24  ARG n 
4 25  ALA n 
4 26  SER n 
4 27  GLN n 
4 28  SER n 
4 29  VAL n 
4 30  SER n 
4 31  SER n 
4 32  TYR n 
4 33  LEU n 
4 34  ALA n 
4 35  TRP n 
4 36  TYR n 
4 37  GLN n 
4 38  GLN n 
4 39  LYS n 
4 40  PRO n 
4 41  GLY n 
4 42  GLN n 
4 43  ALA n 
4 44  PRO n 
4 45  ARG n 
4 46  LEU n 
4 47  LEU n 
4 48  ILE n 
4 49  TYR n 
4 50  GLY n 
4 51  ALA n 
4 52  SER n 
4 53  SER n 
4 54  ARG n 
4 55  ALA n 
4 56  THR n 
4 57  GLY n 
4 58  ILE n 
4 59  PRO n 
4 60  ASP n 
4 61  ARG n 
4 62  PHE n 
4 63  SER n 
4 64  GLY n 
4 65  SER n 
4 66  GLY n 
4 67  SER n 
4 68  GLY n 
4 69  THR n 
4 70  ASP n 
4 71  PHE n 
4 72  THR n 
4 73  LEU n 
4 74  THR n 
4 75  ILE n 
4 76  SER n 
4 77  ARG n 
4 78  LEU n 
4 79  GLU n 
4 80  PRO n 
4 81  GLU n 
4 82  ASP n 
4 83  PHE n 
4 84  ALA n 
4 85  VAL n 
4 86  TYR n 
4 87  TYR n 
4 88  CYS n 
4 89  GLN n 
4 90  GLN n 
4 91  TYR n 
4 92  GLY n 
4 93  SER n 
4 94  SER n 
4 95  PRO n 
4 96  ARG n 
4 97  THR n 
4 98  PHE n 
4 99  GLY n 
4 100 GLN n 
4 101 GLY n 
4 102 THR n 
4 103 LYS n 
4 104 LEU n 
4 105 GLU n 
4 106 ILE n 
4 107 LYS n 
4 108 ARG n 
4 109 THR n 
4 110 VAL n 
4 111 ALA n 
4 112 ALA n 
4 113 PRO n 
4 114 SER n 
4 115 VAL n 
4 116 PHE n 
4 117 ILE n 
4 118 PHE n 
4 119 PRO n 
4 120 PRO n 
4 121 SER n 
4 122 ASP n 
4 123 GLU n 
4 124 GLN n 
4 125 LEU n 
4 126 LYS n 
4 127 SER n 
4 128 GLY n 
4 129 THR n 
4 130 ALA n 
4 131 SER n 
4 132 VAL n 
4 133 VAL n 
4 134 CYS n 
4 135 LEU n 
4 136 LEU n 
4 137 ASN n 
4 138 ASN n 
4 139 PHE n 
4 140 TYR n 
4 141 PRO n 
4 142 ARG n 
4 143 GLU n 
4 144 ALA n 
4 145 LYS n 
4 146 VAL n 
4 147 GLN n 
4 148 TRP n 
4 149 LYS n 
4 150 VAL n 
4 151 ASP n 
4 152 ASN n 
4 153 ALA n 
4 154 LEU n 
4 155 GLN n 
4 156 SER n 
4 157 GLY n 
4 158 ASN n 
4 159 SER n 
4 160 GLN n 
4 161 GLU n 
4 162 SER n 
4 163 VAL n 
4 164 THR n 
4 165 GLU n 
4 166 GLN n 
4 167 ASP n 
4 168 SER n 
4 169 LYS n 
4 170 ASP n 
4 171 SER n 
4 172 THR n 
4 173 TYR n 
4 174 SER n 
4 175 LEU n 
4 176 SER n 
4 177 SER n 
4 178 THR n 
4 179 LEU n 
4 180 THR n 
4 181 LEU n 
4 182 SER n 
4 183 LYS n 
4 184 ALA n 
4 185 ASP n 
4 186 TYR n 
4 187 GLU n 
4 188 LYS n 
4 189 HIS n 
4 190 LYS n 
4 191 VAL n 
4 192 TYR n 
4 193 ALA n 
4 194 CYS n 
4 195 GLU n 
4 196 VAL n 
4 197 THR n 
4 198 HIS n 
4 199 GLN n 
4 200 GLY n 
4 201 LEU n 
4 202 SER n 
4 203 SER n 
4 204 PRO n 
4 205 VAL n 
4 206 THR n 
4 207 LYS n 
4 208 SER n 
4 209 PHE n 
4 210 ASN n 
4 211 ARG n 
4 212 GLY n 
4 213 GLU n 
4 214 CYS n 
5 1   THR n 
5 2   ASN n 
5 3   LEU n 
5 4   CYS n 
5 5   PRO n 
5 6   PHE n 
5 7   GLY n 
5 8   GLU n 
5 9   VAL n 
5 10  PHE n 
5 11  ASN n 
5 12  ALA n 
5 13  THR n 
5 14  ARG n 
5 15  PHE n 
5 16  ALA n 
5 17  SER n 
5 18  VAL n 
5 19  TYR n 
5 20  ALA n 
5 21  TRP n 
5 22  ASN n 
5 23  ARG n 
5 24  LYS n 
5 25  ARG n 
5 26  ILE n 
5 27  SER n 
5 28  ASN n 
5 29  CYS n 
5 30  VAL n 
5 31  ALA n 
5 32  ASP n 
5 33  TYR n 
5 34  SER n 
5 35  VAL n 
5 36  LEU n 
5 37  TYR n 
5 38  ASN n 
5 39  SER n 
5 40  ALA n 
5 41  SER n 
5 42  PHE n 
5 43  SER n 
5 44  THR n 
5 45  PHE n 
5 46  LYS n 
5 47  CYS n 
5 48  TYR n 
5 49  GLY n 
5 50  VAL n 
5 51  SER n 
5 52  PRO n 
5 53  THR n 
5 54  LYS n 
5 55  LEU n 
5 56  ASN n 
5 57  ASP n 
5 58  LEU n 
5 59  CYS n 
5 60  PHE n 
5 61  THR n 
5 62  ASN n 
5 63  VAL n 
5 64  TYR n 
5 65  ALA n 
5 66  ASP n 
5 67  SER n 
5 68  PHE n 
5 69  VAL n 
5 70  ILE n 
5 71  ARG n 
5 72  GLY n 
5 73  ASP n 
5 74  GLU n 
5 75  VAL n 
5 76  ARG n 
5 77  GLN n 
5 78  ILE n 
5 79  ALA n 
5 80  PRO n 
5 81  GLY n 
5 82  GLN n 
5 83  THR n 
5 84  GLY n 
5 85  LYS n 
5 86  ILE n 
5 87  ALA n 
5 88  ASP n 
5 89  TYR n 
5 90  ASN n 
5 91  TYR n 
5 92  LYS n 
5 93  LEU n 
5 94  PRO n 
5 95  ASP n 
5 96  ASP n 
5 97  PHE n 
5 98  THR n 
5 99  GLY n 
5 100 CYS n 
5 101 VAL n 
5 102 ILE n 
5 103 ALA n 
5 104 TRP n 
5 105 ASN n 
5 106 SER n 
5 107 ASN n 
5 108 ASN n 
5 109 LEU n 
5 110 ASP n 
5 111 SER n 
5 112 LYS n 
5 113 VAL n 
5 114 GLY n 
5 115 GLY n 
5 116 ASN n 
5 117 TYR n 
5 118 ASN n 
5 119 TYR n 
5 120 LEU n 
5 121 TYR n 
5 122 ARG n 
5 123 LEU n 
5 124 PHE n 
5 125 ARG n 
5 126 LYS n 
5 127 SER n 
5 128 ASN n 
5 129 LEU n 
5 130 LYS n 
5 131 PRO n 
5 132 PHE n 
5 133 GLU n 
5 134 ARG n 
5 135 ASP n 
5 136 ILE n 
5 137 SER n 
5 138 THR n 
5 139 GLU n 
5 140 ILE n 
5 141 TYR n 
5 142 GLN n 
5 143 ALA n 
5 144 GLY n 
5 145 SER n 
5 146 THR n 
5 147 PRO n 
5 148 CYS n 
5 149 ASN n 
5 150 GLY n 
5 151 VAL n 
5 152 GLU n 
5 153 GLY n 
5 154 PHE n 
5 155 ASN n 
5 156 CYS n 
5 157 TYR n 
5 158 PHE n 
5 159 PRO n 
5 160 LEU n 
5 161 GLN n 
5 162 SER n 
5 163 TYR n 
5 164 GLY n 
5 165 PHE n 
5 166 GLN n 
5 167 PRO n 
5 168 THR n 
5 169 ASN n 
5 170 GLY n 
5 171 VAL n 
5 172 GLY n 
5 173 TYR n 
5 174 GLN n 
5 175 PRO n 
5 176 TYR n 
5 177 ARG n 
5 178 VAL n 
5 179 VAL n 
5 180 VAL n 
5 181 LEU n 
5 182 SER n 
5 183 PHE n 
5 184 GLU n 
5 185 LEU n 
5 186 LEU n 
5 187 HIS n 
5 188 ALA n 
5 189 PRO n 
5 190 ALA n 
5 191 THR n 
5 192 VAL n 
5 193 CYS n 
5 194 GLY n 
5 195 PRO n 
5 196 LYS n 
5 197 LYS n 
5 198 SER n 
5 199 GLY n 
5 200 HIS n 
5 201 HIS n 
5 202 HIS n 
5 203 HIS n 
5 204 HIS n 
5 205 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 222 mouse ? ? ? ? ? ? ? ? 'Mus musculus'                                    10090   ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 220 mouse ? ? ? ? ? ? ? ? 'Mus musculus'                                    10090   ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 220 human ? ? ? ? ? ? ? ? 'Homo sapiens'                                    9606    ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 214 human ? ? ? ? ? ? ? ? 'Homo sapiens'                                    9606    ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 205 ?     ? ? ? ? ? ? ? ? 'Severe acute respiratory syndrome coronavirus 2' 2697049 ? ? ? ? ? ? 
? 'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   6 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 6 DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH                                          'Glycam Condensed Sequence' GMML       1.0   
2 6 'WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5]/1-1-2/a4-b1_b4-c1' WURCS                       PDB2Glycan 1.1.0 
3 6 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}}'           LINUCS                      PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 6 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 6 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking' . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   GLN 3   3   3   GLN GLN H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLN 6   6   6   GLN GLN H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   THR 9   9   9   THR THR H . n 
A 1 10  GLU 10  10  10  GLU GLU H . n 
A 1 11  VAL 11  11  11  VAL VAL H . n 
A 1 12  LYS 12  12  12  LYS LYS H . n 
A 1 13  LYS 13  13  13  LYS LYS H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLU 16  16  16  GLU GLU H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  LYS 19  19  19  LYS LYS H . n 
A 1 20  ILE 20  20  20  ILE ILE H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  LYS 23  23  23  LYS LYS H . n 
A 1 24  GLY 24  24  24  GLY GLY H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  LYS 27  27  27  LYS LYS H . n 
A 1 28  SER 28  28  28  SER SER H . n 
A 1 29  LEU 29  29  29  LEU LEU H . n 
A 1 30  ILE 30  30  30  ILE ILE H . n 
A 1 31  MET 31  31  31  MET MET H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  TRP 33  33  33  TRP TRP H . n 
A 1 34  ILE 34  34  34  ILE ILE H . n 
A 1 35  GLY 35  35  35  GLY GLY H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  MET 40  40  40  MET MET H . n 
A 1 41  PRO 41  41  41  PRO PRO H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  GLY 44  44  44  GLY GLY H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  TRP 47  47  47  TRP TRP H . n 
A 1 48  MET 48  48  48  MET MET H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  ILE 50  50  50  ILE ILE H . n 
A 1 51  ILE 51  51  51  ILE ILE H . n 
A 1 52  TYR 52  52  52  TYR TYR H . n 
A 1 53  PRO 53  52  52  PRO PRO H A n 
A 1 54  GLY 54  53  53  GLY GLY H . n 
A 1 55  ASP 55  54  54  ASP ASP H . n 
A 1 56  SER 56  55  55  SER SER H . n 
A 1 57  ASP 57  56  56  ASP ASP H . n 
A 1 58  THR 58  57  57  THR THR H . n 
A 1 59  ARG 59  58  58  ARG ARG H . n 
A 1 60  TYR 60  59  59  TYR TYR H . n 
A 1 61  SER 61  60  60  SER SER H . n 
A 1 62  PRO 62  61  61  PRO PRO H . n 
A 1 63  SER 63  62  62  SER SER H . n 
A 1 64  PHE 64  63  63  PHE PHE H . n 
A 1 65  GLN 65  64  64  GLN GLN H . n 
A 1 66  GLY 66  65  65  GLY GLY H . n 
A 1 67  GLN 67  66  66  GLN GLN H . n 
A 1 68  VAL 68  67  67  VAL VAL H . n 
A 1 69  THR 69  68  68  THR THR H . n 
A 1 70  ILE 70  69  69  ILE ILE H . n 
A 1 71  SER 71  70  70  SER SER H . n 
A 1 72  ALA 72  71  71  ALA ALA H . n 
A 1 73  ASP 73  72  72  ASP ASP H . n 
A 1 74  LYS 74  73  73  LYS LYS H . n 
A 1 75  SER 75  74  74  SER SER H . n 
A 1 76  ILE 76  75  75  ILE ILE H . n 
A 1 77  ASN 77  76  76  ASN ASN H . n 
A 1 78  THR 78  77  77  THR THR H . n 
A 1 79  ALA 79  78  78  ALA ALA H . n 
A 1 80  TYR 80  79  79  TYR TYR H . n 
A 1 81  LEU 81  80  80  LEU LEU H . n 
A 1 82  GLN 82  81  81  GLN GLN H . n 
A 1 83  TRP 83  82  82  TRP TRP H . n 
A 1 84  SER 84  82  82  SER SER H A n 
A 1 85  SER 85  82  82  SER SER H B n 
A 1 86  LEU 86  82  82  LEU LEU H C n 
A 1 87  LYS 87  83  83  LYS LYS H . n 
A 1 88  ALA 88  84  84  ALA ALA H . n 
A 1 89  SER 89  85  85  SER SER H . n 
A 1 90  ASP 90  86  86  ASP ASP H . n 
A 1 91  THR 91  87  87  THR THR H . n 
A 1 92  ALA 92  88  88  ALA ALA H . n 
A 1 93  MET 93  89  89  MET MET H . n 
A 1 94  TYR 94  90  90  TYR TYR H . n 
A 1 95  TYR 95  91  91  TYR TYR H . n 
A 1 96  CYS 96  92  92  CYS CYS H . n 
A 1 97  ALA 97  93  93  ALA ALA H . n 
A 1 98  GLY 98  94  94  GLY GLY H . n 
A 1 99  GLY 99  95  95  GLY GLY H . n 
A 1 100 SER 100 96  96  SER SER H . n 
A 1 101 GLY 101 97  97  GLY GLY H . n 
A 1 102 ILE 102 98  98  ILE ILE H . n 
A 1 103 PHE 103 99  99  PHE PHE H . n 
A 1 104 THR 104 100 100 THR THR H . n 
A 1 105 PRO 105 100 100 PRO PRO H A n 
A 1 106 MET 106 100 100 MET MET H B n 
A 1 107 ASP 107 101 101 ASP ASP H . n 
A 1 108 VAL 108 102 102 VAL VAL H . n 
A 1 109 TRP 109 103 103 TRP TRP H . n 
A 1 110 GLY 110 104 104 GLY GLY H . n 
A 1 111 GLN 111 105 105 GLN GLN H . n 
A 1 112 GLY 112 106 106 GLY GLY H . n 
A 1 113 THR 113 107 107 THR THR H . n 
A 1 114 ALA 114 108 108 ALA ALA H . n 
A 1 115 VAL 115 109 109 VAL VAL H . n 
A 1 116 ALA 116 110 110 ALA ALA H . n 
A 1 117 VAL 117 111 111 VAL VAL H . n 
A 1 118 SER 118 112 112 SER SER H . n 
A 1 119 SER 119 113 113 SER SER H . n 
A 1 120 ALA 120 114 114 ALA ALA H . n 
A 1 121 SER 121 115 115 SER SER H . n 
A 1 122 THR 122 116 116 THR THR H . n 
A 1 123 LYS 123 117 117 LYS LYS H . n 
A 1 124 GLY 124 118 118 GLY GLY H . n 
A 1 125 PRO 125 119 119 PRO PRO H . n 
A 1 126 SER 126 120 120 SER SER H . n 
A 1 127 VAL 127 121 121 VAL VAL H . n 
A 1 128 PHE 128 122 122 PHE PHE H . n 
A 1 129 PRO 129 123 123 PRO PRO H . n 
A 1 130 LEU 130 124 124 LEU LEU H . n 
A 1 131 ALA 131 125 125 ALA ALA H . n 
A 1 132 PRO 132 126 126 PRO PRO H . n 
A 1 133 SER 133 127 127 SER SER H . n 
A 1 134 SER 134 128 128 SER SER H . n 
A 1 135 LYS 135 129 129 LYS LYS H . n 
A 1 136 SER 136 130 130 SER SER H . n 
A 1 137 THR 137 131 131 THR THR H . n 
A 1 138 SER 138 132 132 SER SER H . n 
A 1 139 GLY 139 133 133 GLY GLY H . n 
A 1 140 GLY 140 134 134 GLY GLY H . n 
A 1 141 THR 141 135 135 THR THR H . n 
A 1 142 ALA 142 136 136 ALA ALA H . n 
A 1 143 ALA 143 137 137 ALA ALA H . n 
A 1 144 LEU 144 138 138 LEU LEU H . n 
A 1 145 GLY 145 139 139 GLY GLY H . n 
A 1 146 CYS 146 140 140 CYS CYS H . n 
A 1 147 LEU 147 141 141 LEU LEU H . n 
A 1 148 VAL 148 142 142 VAL VAL H . n 
A 1 149 LYS 149 143 143 LYS LYS H . n 
A 1 150 ASP 150 144 144 ASP ASP H . n 
A 1 151 TYR 151 145 145 TYR TYR H . n 
A 1 152 PHE 152 146 146 PHE PHE H . n 
A 1 153 PRO 153 147 147 PRO PRO H . n 
A 1 154 GLU 154 148 148 GLU GLU H . n 
A 1 155 PRO 155 149 149 PRO PRO H . n 
A 1 156 VAL 156 150 150 VAL VAL H . n 
A 1 157 THR 157 151 151 THR THR H . n 
A 1 158 VAL 158 152 152 VAL VAL H . n 
A 1 159 SER 159 153 153 SER SER H . n 
A 1 160 TRP 160 154 154 TRP TRP H . n 
A 1 161 ASN 161 155 155 ASN ASN H . n 
A 1 162 SER 162 156 156 SER SER H . n 
A 1 163 GLY 163 157 157 GLY GLY H . n 
A 1 164 ALA 164 158 158 ALA ALA H . n 
A 1 165 LEU 165 159 159 LEU LEU H . n 
A 1 166 THR 166 160 160 THR THR H . n 
A 1 167 SER 167 161 161 SER SER H . n 
A 1 168 GLY 168 162 162 GLY GLY H . n 
A 1 169 VAL 169 163 163 VAL VAL H . n 
A 1 170 HIS 170 164 164 HIS HIS H . n 
A 1 171 THR 171 165 165 THR THR H . n 
A 1 172 PHE 172 166 166 PHE PHE H . n 
A 1 173 PRO 173 167 167 PRO PRO H . n 
A 1 174 ALA 174 168 168 ALA ALA H . n 
A 1 175 VAL 175 169 169 VAL VAL H . n 
A 1 176 LEU 176 170 170 LEU LEU H . n 
A 1 177 GLN 177 171 171 GLN GLN H . n 
A 1 178 SER 178 172 172 SER SER H . n 
A 1 179 SER 179 173 173 SER SER H . n 
A 1 180 GLY 180 174 174 GLY GLY H . n 
A 1 181 LEU 181 175 175 LEU LEU H . n 
A 1 182 TYR 182 176 176 TYR TYR H . n 
A 1 183 SER 183 177 177 SER SER H . n 
A 1 184 LEU 184 178 178 LEU LEU H . n 
A 1 185 SER 185 179 179 SER SER H . n 
A 1 186 SER 186 180 180 SER SER H . n 
A 1 187 VAL 187 181 181 VAL VAL H . n 
A 1 188 VAL 188 182 182 VAL VAL H . n 
A 1 189 THR 189 183 183 THR THR H . n 
A 1 190 VAL 190 184 184 VAL VAL H . n 
A 1 191 PRO 191 185 185 PRO PRO H . n 
A 1 192 SER 192 186 186 SER SER H . n 
A 1 193 SER 193 187 187 SER SER H . n 
A 1 194 SER 194 188 188 SER SER H . n 
A 1 195 LEU 195 189 189 LEU LEU H . n 
A 1 196 GLY 196 190 190 GLY GLY H . n 
A 1 197 THR 197 191 191 THR THR H . n 
A 1 198 GLN 198 192 192 GLN GLN H . n 
A 1 199 THR 199 193 193 THR THR H . n 
A 1 200 TYR 200 194 194 TYR TYR H . n 
A 1 201 ILE 201 195 195 ILE ILE H . n 
A 1 202 CYS 202 196 196 CYS CYS H . n 
A 1 203 ASN 203 197 197 ASN ASN H . n 
A 1 204 VAL 204 198 198 VAL VAL H . n 
A 1 205 ASN 205 199 199 ASN ASN H . n 
A 1 206 HIS 206 200 200 HIS HIS H . n 
A 1 207 LYS 207 201 201 LYS LYS H . n 
A 1 208 PRO 208 202 202 PRO PRO H . n 
A 1 209 SER 209 203 203 SER SER H . n 
A 1 210 ASN 210 204 204 ASN ASN H . n 
A 1 211 THR 211 205 205 THR THR H . n 
A 1 212 LYS 212 206 206 LYS LYS H . n 
A 1 213 VAL 213 207 207 VAL VAL H . n 
A 1 214 ASP 214 208 208 ASP ASP H . n 
A 1 215 LYS 215 209 209 LYS LYS H . n 
A 1 216 LYS 216 210 210 LYS LYS H . n 
A 1 217 VAL 217 211 211 VAL VAL H . n 
A 1 218 GLU 218 212 212 GLU GLU H . n 
A 1 219 PRO 219 213 213 PRO PRO H . n 
A 1 220 LYS 220 214 214 LYS LYS H . n 
A 1 221 SER 221 215 ?   ?   ?   H . n 
A 1 222 CYS 222 216 ?   ?   ?   H . n 
B 2 1   ASP 1   1   1   ASP ASP L . n 
B 2 2   ILE 2   2   2   ILE ILE L . n 
B 2 3   GLN 3   3   3   GLN GLN L . n 
B 2 4   LEU 4   4   4   LEU LEU L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   ASP 9   9   9   ASP ASP L . n 
B 2 10  SER 10  10  10  SER SER L . n 
B 2 11  LEU 11  11  11  LEU LEU L . n 
B 2 12  ALA 12  12  12  ALA ALA L . n 
B 2 13  VAL 13  13  13  VAL VAL L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  LEU 15  15  15  LEU LEU L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  GLU 17  17  17  GLU GLU L . n 
B 2 18  ARG 18  18  18  ARG ARG L . n 
B 2 19  ALA 19  19  19  ALA ALA L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  ILE 21  21  21  ILE ILE L . n 
B 2 22  ASN 22  22  22  ASN ASN L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  LYS 24  24  24  LYS LYS L . n 
B 2 25  SER 25  25  25  SER SER L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  GLN 27  27  27  GLN GLN L . n 
B 2 28  SER 28  27  27  SER SER L A n 
B 2 29  VAL 29  27  27  VAL VAL L B n 
B 2 30  LEU 30  27  27  LEU LEU L C n 
B 2 31  TYR 31  27  27  TYR TYR L D n 
B 2 32  SER 32  27  27  SER SER L E n 
B 2 33  SER 33  27  27  SER SER L F n 
B 2 34  ILE 34  28  28  ILE ILE L . n 
B 2 35  ASN 35  29  29  ASN ASN L . n 
B 2 36  LYS 36  30  30  LYS LYS L . n 
B 2 37  ASN 37  31  31  ASN ASN L . n 
B 2 38  TYR 38  32  32  TYR TYR L . n 
B 2 39  LEU 39  33  33  LEU LEU L . n 
B 2 40  ALA 40  34  34  ALA ALA L . n 
B 2 41  TRP 41  35  35  TRP TRP L . n 
B 2 42  TYR 42  36  36  TYR TYR L . n 
B 2 43  GLN 43  37  37  GLN GLN L . n 
B 2 44  GLN 44  38  38  GLN GLN L . n 
B 2 45  LYS 45  39  39  LYS LYS L . n 
B 2 46  PRO 46  40  40  PRO PRO L . n 
B 2 47  GLY 47  41  41  GLY GLY L . n 
B 2 48  GLN 48  42  42  GLN GLN L . n 
B 2 49  PRO 49  43  43  PRO PRO L . n 
B 2 50  PRO 50  44  44  PRO PRO L . n 
B 2 51  LYS 51  45  45  LYS LYS L . n 
B 2 52  LEU 52  46  46  LEU LEU L . n 
B 2 53  LEU 53  47  47  LEU LEU L . n 
B 2 54  ILE 54  48  48  ILE ILE L . n 
B 2 55  TYR 55  49  49  TYR TYR L . n 
B 2 56  TRP 56  50  50  TRP TRP L . n 
B 2 57  ALA 57  51  51  ALA ALA L . n 
B 2 58  SER 58  52  52  SER SER L . n 
B 2 59  THR 59  53  53  THR THR L . n 
B 2 60  ARG 60  54  54  ARG ARG L . n 
B 2 61  GLU 61  55  55  GLU GLU L . n 
B 2 62  SER 62  56  56  SER SER L . n 
B 2 63  GLY 63  57  57  GLY GLY L . n 
B 2 64  VAL 64  58  58  VAL VAL L . n 
B 2 65  PRO 65  59  59  PRO PRO L . n 
B 2 66  ASP 66  60  60  ASP ASP L . n 
B 2 67  ARG 67  61  61  ARG ARG L . n 
B 2 68  PHE 68  62  62  PHE PHE L . n 
B 2 69  SER 69  63  63  SER SER L . n 
B 2 70  GLY 70  64  64  GLY GLY L . n 
B 2 71  SER 71  65  65  SER SER L . n 
B 2 72  GLY 72  66  66  GLY GLY L . n 
B 2 73  SER 73  67  67  SER SER L . n 
B 2 74  GLY 74  68  68  GLY GLY L . n 
B 2 75  THR 75  69  69  THR THR L . n 
B 2 76  ASP 76  70  70  ASP ASP L . n 
B 2 77  PHE 77  71  71  PHE PHE L . n 
B 2 78  THR 78  72  72  THR THR L . n 
B 2 79  LEU 79  73  73  LEU LEU L . n 
B 2 80  THR 80  74  74  THR THR L . n 
B 2 81  ILE 81  75  75  ILE ILE L . n 
B 2 82  SER 82  76  76  SER SER L . n 
B 2 83  SER 83  77  77  SER SER L . n 
B 2 84  LEU 84  78  78  LEU LEU L . n 
B 2 85  GLN 85  79  79  GLN GLN L . n 
B 2 86  ALA 86  80  80  ALA ALA L . n 
B 2 87  GLU 87  81  81  GLU GLU L . n 
B 2 88  ASP 88  82  82  ASP ASP L . n 
B 2 89  VAL 89  83  83  VAL VAL L . n 
B 2 90  ALA 90  84  84  ALA ALA L . n 
B 2 91  VAL 91  85  85  VAL VAL L . n 
B 2 92  TYR 92  86  86  TYR TYR L . n 
B 2 93  TYR 93  87  87  TYR TYR L . n 
B 2 94  CYS 94  88  88  CYS CYS L . n 
B 2 95  GLN 95  89  89  GLN GLN L . n 
B 2 96  GLN 96  90  90  GLN GLN L . n 
B 2 97  TYR 97  91  91  TYR TYR L . n 
B 2 98  TYR 98  92  92  TYR TYR L . n 
B 2 99  SER 99  93  93  SER SER L . n 
B 2 100 THR 100 94  94  THR THR L . n 
B 2 101 PRO 101 95  95  PRO PRO L . n 
B 2 102 TYR 102 96  96  TYR TYR L . n 
B 2 103 THR 103 97  97  THR THR L . n 
B 2 104 PHE 104 98  98  PHE PHE L . n 
B 2 105 GLY 105 99  99  GLY GLY L . n 
B 2 106 GLN 106 100 100 GLN GLN L . n 
B 2 107 GLY 107 101 101 GLY GLY L . n 
B 2 108 THR 108 102 102 THR THR L . n 
B 2 109 LYS 109 103 103 LYS LYS L . n 
B 2 110 VAL 110 104 104 VAL VAL L . n 
B 2 111 GLU 111 105 105 GLU GLU L . n 
B 2 112 ILE 112 106 106 ILE ILE L . n 
B 2 113 LYS 113 107 107 LYS LYS L . n 
B 2 114 ARG 114 108 108 ARG ARG L . n 
B 2 115 THR 115 109 109 THR THR L . n 
B 2 116 VAL 116 110 110 VAL VAL L . n 
B 2 117 ALA 117 111 111 ALA ALA L . n 
B 2 118 ALA 118 112 112 ALA ALA L . n 
B 2 119 PRO 119 113 113 PRO PRO L . n 
B 2 120 SER 120 114 114 SER SER L . n 
B 2 121 VAL 121 115 115 VAL VAL L . n 
B 2 122 PHE 122 116 116 PHE PHE L . n 
B 2 123 ILE 123 117 117 ILE ILE L . n 
B 2 124 PHE 124 118 118 PHE PHE L . n 
B 2 125 PRO 125 119 119 PRO PRO L . n 
B 2 126 PRO 126 120 120 PRO PRO L . n 
B 2 127 SER 127 121 121 SER SER L . n 
B 2 128 ASP 128 122 122 ASP ASP L . n 
B 2 129 GLU 129 123 123 GLU GLU L . n 
B 2 130 GLN 130 124 124 GLN GLN L . n 
B 2 131 LEU 131 125 125 LEU LEU L . n 
B 2 132 LYS 132 126 126 LYS LYS L . n 
B 2 133 SER 133 127 127 SER SER L . n 
B 2 134 GLY 134 128 128 GLY GLY L . n 
B 2 135 THR 135 129 129 THR THR L . n 
B 2 136 ALA 136 130 130 ALA ALA L . n 
B 2 137 SER 137 131 131 SER SER L . n 
B 2 138 VAL 138 132 132 VAL VAL L . n 
B 2 139 VAL 139 133 133 VAL VAL L . n 
B 2 140 CYS 140 134 134 CYS CYS L . n 
B 2 141 LEU 141 135 135 LEU LEU L . n 
B 2 142 LEU 142 136 136 LEU LEU L . n 
B 2 143 ASN 143 137 137 ASN ASN L . n 
B 2 144 ASN 144 138 138 ASN ASN L . n 
B 2 145 PHE 145 139 139 PHE PHE L . n 
B 2 146 TYR 146 140 140 TYR TYR L . n 
B 2 147 PRO 147 141 141 PRO PRO L . n 
B 2 148 ARG 148 142 142 ARG ARG L . n 
B 2 149 GLU 149 143 143 GLU GLU L . n 
B 2 150 ALA 150 144 144 ALA ALA L . n 
B 2 151 LYS 151 145 145 LYS LYS L . n 
B 2 152 VAL 152 146 146 VAL VAL L . n 
B 2 153 GLN 153 147 147 GLN GLN L . n 
B 2 154 TRP 154 148 148 TRP TRP L . n 
B 2 155 LYS 155 149 149 LYS LYS L . n 
B 2 156 VAL 156 150 150 VAL VAL L . n 
B 2 157 ASP 157 151 151 ASP ASP L . n 
B 2 158 ASN 158 152 152 ASN ASN L . n 
B 2 159 ALA 159 153 153 ALA ALA L . n 
B 2 160 LEU 160 154 154 LEU LEU L . n 
B 2 161 GLN 161 155 155 GLN GLN L . n 
B 2 162 SER 162 156 156 SER SER L . n 
B 2 163 GLY 163 157 157 GLY GLY L . n 
B 2 164 ASN 164 158 158 ASN ASN L . n 
B 2 165 SER 165 159 159 SER SER L . n 
B 2 166 GLN 166 160 160 GLN GLN L . n 
B 2 167 GLU 167 161 161 GLU GLU L . n 
B 2 168 SER 168 162 162 SER SER L . n 
B 2 169 VAL 169 163 163 VAL VAL L . n 
B 2 170 THR 170 164 164 THR THR L . n 
B 2 171 GLU 171 165 165 GLU GLU L . n 
B 2 172 GLN 172 166 166 GLN GLN L . n 
B 2 173 ASP 173 167 167 ASP ASP L . n 
B 2 174 SER 174 168 168 SER SER L . n 
B 2 175 LYS 175 169 169 LYS LYS L . n 
B 2 176 ASP 176 170 170 ASP ASP L . n 
B 2 177 SER 177 171 171 SER SER L . n 
B 2 178 THR 178 172 172 THR THR L . n 
B 2 179 TYR 179 173 173 TYR TYR L . n 
B 2 180 SER 180 174 174 SER SER L . n 
B 2 181 LEU 181 175 175 LEU LEU L . n 
B 2 182 SER 182 176 176 SER SER L . n 
B 2 183 SER 183 177 177 SER SER L . n 
B 2 184 THR 184 178 178 THR THR L . n 
B 2 185 LEU 185 179 179 LEU LEU L . n 
B 2 186 THR 186 180 180 THR THR L . n 
B 2 187 LEU 187 181 181 LEU LEU L . n 
B 2 188 SER 188 182 182 SER SER L . n 
B 2 189 LYS 189 183 183 LYS LYS L . n 
B 2 190 ALA 190 184 184 ALA ALA L . n 
B 2 191 ASP 191 185 185 ASP ASP L . n 
B 2 192 TYR 192 186 186 TYR TYR L . n 
B 2 193 GLU 193 187 187 GLU GLU L . n 
B 2 194 LYS 194 188 188 LYS LYS L . n 
B 2 195 HIS 195 189 189 HIS HIS L . n 
B 2 196 LYS 196 190 190 LYS LYS L . n 
B 2 197 VAL 197 191 191 VAL VAL L . n 
B 2 198 TYR 198 192 192 TYR TYR L . n 
B 2 199 ALA 199 193 193 ALA ALA L . n 
B 2 200 CYS 200 194 194 CYS CYS L . n 
B 2 201 GLU 201 195 195 GLU GLU L . n 
B 2 202 VAL 202 196 196 VAL VAL L . n 
B 2 203 THR 203 197 197 THR THR L . n 
B 2 204 HIS 204 198 198 HIS HIS L . n 
B 2 205 GLN 205 199 199 GLN GLN L . n 
B 2 206 GLY 206 200 200 GLY GLY L . n 
B 2 207 LEU 207 201 201 LEU LEU L . n 
B 2 208 SER 208 202 202 SER SER L . n 
B 2 209 SER 209 203 203 SER SER L . n 
B 2 210 PRO 210 204 204 PRO PRO L . n 
B 2 211 VAL 211 205 205 VAL VAL L . n 
B 2 212 THR 212 206 206 THR THR L . n 
B 2 213 LYS 213 207 207 LYS LYS L . n 
B 2 214 SER 214 208 208 SER SER L . n 
B 2 215 PHE 215 209 209 PHE PHE L . n 
B 2 216 ASN 216 210 210 ASN ASN L . n 
B 2 217 ARG 217 211 211 ARG ARG L . n 
B 2 218 GLY 218 212 212 GLY GLY L . n 
B 2 219 GLU 219 213 ?   ?   ?   L . n 
B 2 220 CYS 220 214 ?   ?   ?   L . n 
C 3 1   GLN 1   1   1   GLN GLN C . n 
C 3 2   VAL 2   2   2   VAL VAL C . n 
C 3 3   GLN 3   3   3   GLN GLN C . n 
C 3 4   LEU 4   4   4   LEU LEU C . n 
C 3 5   VAL 5   5   5   VAL VAL C . n 
C 3 6   GLU 6   6   6   GLU GLU C . n 
C 3 7   SER 7   7   7   SER SER C . n 
C 3 8   GLY 8   8   8   GLY GLY C . n 
C 3 9   GLY 9   9   9   GLY GLY C . n 
C 3 10  GLY 10  10  10  GLY GLY C . n 
C 3 11  LEU 11  11  11  LEU LEU C . n 
C 3 12  ILE 12  12  12  ILE ILE C . n 
C 3 13  GLN 13  13  13  GLN GLN C . n 
C 3 14  PRO 14  14  14  PRO PRO C . n 
C 3 15  GLY 15  15  15  GLY GLY C . n 
C 3 16  GLY 16  16  16  GLY GLY C . n 
C 3 17  SER 17  17  17  SER SER C . n 
C 3 18  LEU 18  18  18  LEU LEU C . n 
C 3 19  ARG 19  19  19  ARG ARG C . n 
C 3 20  LEU 20  20  20  LEU LEU C . n 
C 3 21  SER 21  21  21  SER SER C . n 
C 3 22  CYS 22  22  22  CYS CYS C . n 
C 3 23  ALA 23  23  23  ALA ALA C . n 
C 3 24  ALA 24  24  24  ALA ALA C . n 
C 3 25  SER 25  25  25  SER SER C . n 
C 3 26  GLY 26  26  26  GLY GLY C . n 
C 3 27  PHE 27  27  27  PHE PHE C . n 
C 3 28  THR 28  28  28  THR THR C . n 
C 3 29  VAL 29  29  29  VAL VAL C . n 
C 3 30  SER 30  30  30  SER SER C . n 
C 3 31  SER 31  31  31  SER SER C . n 
C 3 32  ASN 32  32  32  ASN ASN C . n 
C 3 33  TYR 33  33  33  TYR TYR C . n 
C 3 34  MET 34  34  34  MET MET C . n 
C 3 35  SER 35  35  35  SER SER C . n 
C 3 36  TRP 36  36  36  TRP TRP C . n 
C 3 37  VAL 37  37  37  VAL VAL C . n 
C 3 38  ARG 38  38  38  ARG ARG C . n 
C 3 39  GLN 39  39  39  GLN GLN C . n 
C 3 40  ALA 40  40  40  ALA ALA C . n 
C 3 41  PRO 41  41  41  PRO PRO C . n 
C 3 42  GLY 42  42  42  GLY GLY C . n 
C 3 43  LYS 43  43  43  LYS LYS C . n 
C 3 44  GLY 44  44  44  GLY GLY C . n 
C 3 45  LEU 45  45  45  LEU LEU C . n 
C 3 46  GLU 46  46  46  GLU GLU C . n 
C 3 47  TRP 47  47  47  TRP TRP C . n 
C 3 48  VAL 48  48  48  VAL VAL C . n 
C 3 49  SER 49  49  49  SER SER C . n 
C 3 50  VAL 50  50  50  VAL VAL C . n 
C 3 51  ILE 51  51  51  ILE ILE C . n 
C 3 52  TYR 52  52  52  TYR TYR C . n 
C 3 53  SER 53  53  53  SER SER C . n 
C 3 54  GLY 54  54  54  GLY GLY C . n 
C 3 55  GLY 55  55  55  GLY GLY C . n 
C 3 56  SER 56  56  56  SER SER C . n 
C 3 57  THR 57  57  57  THR THR C . n 
C 3 58  PHE 58  58  58  PHE PHE C . n 
C 3 59  TYR 59  59  59  TYR TYR C . n 
C 3 60  ALA 60  60  60  ALA ALA C . n 
C 3 61  ASP 61  61  61  ASP ASP C . n 
C 3 62  SER 62  62  62  SER SER C . n 
C 3 63  VAL 63  63  63  VAL VAL C . n 
C 3 64  LYS 64  64  64  LYS LYS C . n 
C 3 65  GLY 65  65  65  GLY GLY C . n 
C 3 66  ARG 66  66  66  ARG ARG C . n 
C 3 67  PHE 67  67  67  PHE PHE C . n 
C 3 68  THR 68  68  68  THR THR C . n 
C 3 69  ILE 69  69  69  ILE ILE C . n 
C 3 70  SER 70  70  70  SER SER C . n 
C 3 71  ARG 71  71  71  ARG ARG C . n 
C 3 72  ASP 72  72  72  ASP ASP C . n 
C 3 73  ASN 73  73  73  ASN ASN C . n 
C 3 74  SER 74  74  74  SER SER C . n 
C 3 75  LYS 75  75  75  LYS LYS C . n 
C 3 76  SER 76  76  76  SER SER C . n 
C 3 77  THR 77  77  77  THR THR C . n 
C 3 78  LEU 78  78  78  LEU LEU C . n 
C 3 79  TYR 79  79  79  TYR TYR C . n 
C 3 80  LEU 80  80  80  LEU LEU C . n 
C 3 81  GLN 81  81  81  GLN GLN C . n 
C 3 82  MET 82  82  82  MET MET C . n 
C 3 83  ASN 83  82  82  ASN ASN C A n 
C 3 84  SER 84  82  82  SER SER C B n 
C 3 85  LEU 85  82  82  LEU LEU C C n 
C 3 86  ARG 86  83  83  ARG ARG C . n 
C 3 87  VAL 87  84  84  VAL VAL C . n 
C 3 88  GLU 88  85  85  GLU GLU C . n 
C 3 89  ASP 89  86  86  ASP ASP C . n 
C 3 90  THR 90  87  87  THR THR C . n 
C 3 91  ALA 91  88  88  ALA ALA C . n 
C 3 92  VAL 92  89  89  VAL VAL C . n 
C 3 93  TYR 93  90  90  TYR TYR C . n 
C 3 94  TYR 94  91  91  TYR TYR C . n 
C 3 95  CYS 95  92  92  CYS CYS C . n 
C 3 96  ALA 96  93  93  ALA ALA C . n 
C 3 97  ARG 97  94  94  ARG ARG C . n 
C 3 98  ASP 98  95  95  ASP ASP C . n 
C 3 99  PHE 99  96  96  PHE PHE C . n 
C 3 100 GLY 100 97  97  GLY GLY C . n 
C 3 101 ASP 101 98  98  ASP ASP C . n 
C 3 102 PHE 102 99  99  PHE PHE C . n 
C 3 103 TYR 103 100 100 TYR TYR C . n 
C 3 104 PHE 104 100 100 PHE PHE C A n 
C 3 105 ASP 105 101 101 ASP ASP C . n 
C 3 106 TYR 106 102 102 TYR TYR C . n 
C 3 107 TRP 107 103 103 TRP TRP C . n 
C 3 108 GLY 108 104 104 GLY GLY C . n 
C 3 109 GLN 109 105 105 GLN GLN C . n 
C 3 110 GLY 110 106 106 GLY GLY C . n 
C 3 111 THR 111 107 107 THR THR C . n 
C 3 112 LEU 112 108 108 LEU LEU C . n 
C 3 113 VAL 113 109 109 VAL VAL C . n 
C 3 114 THR 114 110 110 THR THR C . n 
C 3 115 VAL 115 111 111 VAL VAL C . n 
C 3 116 SER 116 112 112 SER SER C . n 
C 3 117 SER 117 113 113 SER SER C . n 
C 3 118 ALA 118 114 114 ALA ALA C . n 
C 3 119 SER 119 115 115 SER SER C . n 
C 3 120 THR 120 116 116 THR THR C . n 
C 3 121 LYS 121 117 117 LYS LYS C . n 
C 3 122 GLY 122 118 118 GLY GLY C . n 
C 3 123 PRO 123 119 119 PRO PRO C . n 
C 3 124 SER 124 120 120 SER SER C . n 
C 3 125 VAL 125 121 121 VAL VAL C . n 
C 3 126 PHE 126 122 122 PHE PHE C . n 
C 3 127 PRO 127 123 123 PRO PRO C . n 
C 3 128 LEU 128 124 124 LEU LEU C . n 
C 3 129 ALA 129 125 125 ALA ALA C . n 
C 3 130 PRO 130 126 126 PRO PRO C . n 
C 3 131 SER 131 127 127 SER SER C . n 
C 3 132 SER 132 128 128 SER SER C . n 
C 3 133 LYS 133 129 ?   ?   ?   C . n 
C 3 134 SER 134 130 ?   ?   ?   C . n 
C 3 135 THR 135 131 ?   ?   ?   C . n 
C 3 136 SER 136 132 ?   ?   ?   C . n 
C 3 137 GLY 137 133 ?   ?   ?   C . n 
C 3 138 GLY 138 134 134 GLY GLY C . n 
C 3 139 THR 139 135 135 THR THR C . n 
C 3 140 ALA 140 136 136 ALA ALA C . n 
C 3 141 ALA 141 137 137 ALA ALA C . n 
C 3 142 LEU 142 138 138 LEU LEU C . n 
C 3 143 GLY 143 139 139 GLY GLY C . n 
C 3 144 CYS 144 140 140 CYS CYS C . n 
C 3 145 LEU 145 141 141 LEU LEU C . n 
C 3 146 VAL 146 142 142 VAL VAL C . n 
C 3 147 LYS 147 143 143 LYS LYS C . n 
C 3 148 ASP 148 144 144 ASP ASP C . n 
C 3 149 TYR 149 145 145 TYR TYR C . n 
C 3 150 PHE 150 146 146 PHE PHE C . n 
C 3 151 PRO 151 147 147 PRO PRO C . n 
C 3 152 GLU 152 148 148 GLU GLU C . n 
C 3 153 PRO 153 149 149 PRO PRO C . n 
C 3 154 VAL 154 150 150 VAL VAL C . n 
C 3 155 THR 155 151 151 THR THR C . n 
C 3 156 VAL 156 152 152 VAL VAL C . n 
C 3 157 SER 157 153 153 SER SER C . n 
C 3 158 TRP 158 154 154 TRP TRP C . n 
C 3 159 ASN 159 155 155 ASN ASN C . n 
C 3 160 SER 160 156 156 SER SER C . n 
C 3 161 GLY 161 157 157 GLY GLY C . n 
C 3 162 ALA 162 158 158 ALA ALA C . n 
C 3 163 LEU 163 159 ?   ?   ?   C . n 
C 3 164 THR 164 160 160 THR THR C . n 
C 3 165 SER 165 161 161 SER SER C . n 
C 3 166 GLY 166 162 162 GLY GLY C . n 
C 3 167 VAL 167 163 163 VAL VAL C . n 
C 3 168 HIS 168 164 164 HIS HIS C . n 
C 3 169 THR 169 165 165 THR THR C . n 
C 3 170 PHE 170 166 166 PHE PHE C . n 
C 3 171 PRO 171 167 167 PRO PRO C . n 
C 3 172 ALA 172 168 168 ALA ALA C . n 
C 3 173 VAL 173 169 169 VAL VAL C . n 
C 3 174 LEU 174 170 170 LEU LEU C . n 
C 3 175 GLN 175 171 171 GLN GLN C . n 
C 3 176 SER 176 172 172 SER SER C . n 
C 3 177 SER 177 173 173 SER SER C . n 
C 3 178 GLY 178 174 174 GLY GLY C . n 
C 3 179 LEU 179 175 175 LEU LEU C . n 
C 3 180 TYR 180 176 176 TYR TYR C . n 
C 3 181 SER 181 177 177 SER SER C . n 
C 3 182 LEU 182 178 178 LEU LEU C . n 
C 3 183 SER 183 179 179 SER SER C . n 
C 3 184 SER 184 180 180 SER SER C . n 
C 3 185 VAL 185 181 181 VAL VAL C . n 
C 3 186 VAL 186 182 182 VAL VAL C . n 
C 3 187 THR 187 183 183 THR THR C . n 
C 3 188 VAL 188 184 184 VAL VAL C . n 
C 3 189 PRO 189 185 185 PRO PRO C . n 
C 3 190 SER 190 186 186 SER SER C . n 
C 3 191 SER 191 187 187 SER SER C . n 
C 3 192 SER 192 188 188 SER SER C . n 
C 3 193 LEU 193 189 189 LEU LEU C . n 
C 3 194 GLY 194 190 190 GLY GLY C . n 
C 3 195 THR 195 191 191 THR THR C . n 
C 3 196 GLN 196 192 192 GLN GLN C . n 
C 3 197 THR 197 193 193 THR THR C . n 
C 3 198 TYR 198 194 194 TYR TYR C . n 
C 3 199 ILE 199 195 195 ILE ILE C . n 
C 3 200 CYS 200 196 196 CYS CYS C . n 
C 3 201 ASN 201 197 197 ASN ASN C . n 
C 3 202 VAL 202 198 198 VAL VAL C . n 
C 3 203 ASN 203 199 199 ASN ASN C . n 
C 3 204 HIS 204 200 200 HIS HIS C . n 
C 3 205 LYS 205 201 201 LYS LYS C . n 
C 3 206 PRO 206 202 202 PRO PRO C . n 
C 3 207 SER 207 203 203 SER SER C . n 
C 3 208 ASN 208 204 204 ASN ASN C . n 
C 3 209 THR 209 205 205 THR THR C . n 
C 3 210 LYS 210 206 206 LYS LYS C . n 
C 3 211 VAL 211 207 207 VAL VAL C . n 
C 3 212 ASP 212 208 208 ASP ASP C . n 
C 3 213 LYS 213 209 209 LYS LYS C . n 
C 3 214 LYS 214 210 210 LYS LYS C . n 
C 3 215 VAL 215 211 211 VAL VAL C . n 
C 3 216 GLU 216 212 212 GLU GLU C . n 
C 3 217 PRO 217 213 213 PRO PRO C . n 
C 3 218 LYS 218 214 ?   ?   ?   C . n 
C 3 219 SER 219 215 ?   ?   ?   C . n 
C 3 220 CYS 220 216 ?   ?   ?   C . n 
D 4 1   GLU 1   1   1   GLU GLU D . n 
D 4 2   ILE 2   2   2   ILE ILE D . n 
D 4 3   VAL 3   3   3   VAL VAL D . n 
D 4 4   LEU 4   4   4   LEU LEU D . n 
D 4 5   THR 5   5   5   THR THR D . n 
D 4 6   GLN 6   6   6   GLN GLN D . n 
D 4 7   SER 7   7   7   SER SER D . n 
D 4 8   PRO 8   8   8   PRO PRO D . n 
D 4 9   GLY 9   9   9   GLY GLY D . n 
D 4 10  THR 10  10  10  THR THR D . n 
D 4 11  LEU 11  11  11  LEU LEU D . n 
D 4 12  SER 12  12  12  SER SER D . n 
D 4 13  LEU 13  13  13  LEU LEU D . n 
D 4 14  SER 14  14  14  SER SER D . n 
D 4 15  PRO 15  15  15  PRO PRO D . n 
D 4 16  GLY 16  16  16  GLY GLY D . n 
D 4 17  GLU 17  17  17  GLU GLU D . n 
D 4 18  ARG 18  18  18  ARG ARG D . n 
D 4 19  ALA 19  19  19  ALA ALA D . n 
D 4 20  THR 20  20  20  THR THR D . n 
D 4 21  LEU 21  21  21  LEU LEU D . n 
D 4 22  SER 22  22  22  SER SER D . n 
D 4 23  CYS 23  23  23  CYS CYS D . n 
D 4 24  ARG 24  24  24  ARG ARG D . n 
D 4 25  ALA 25  25  25  ALA ALA D . n 
D 4 26  SER 26  26  26  SER SER D . n 
D 4 27  GLN 27  27  27  GLN GLN D . n 
D 4 28  SER 28  28  28  SER SER D . n 
D 4 29  VAL 29  29  29  VAL VAL D . n 
D 4 30  SER 30  30  30  SER SER D . n 
D 4 31  SER 31  31  31  SER SER D . n 
D 4 32  TYR 32  32  32  TYR TYR D . n 
D 4 33  LEU 33  33  33  LEU LEU D . n 
D 4 34  ALA 34  34  34  ALA ALA D . n 
D 4 35  TRP 35  35  35  TRP TRP D . n 
D 4 36  TYR 36  36  36  TYR TYR D . n 
D 4 37  GLN 37  37  37  GLN GLN D . n 
D 4 38  GLN 38  38  38  GLN GLN D . n 
D 4 39  LYS 39  39  39  LYS LYS D . n 
D 4 40  PRO 40  40  40  PRO PRO D . n 
D 4 41  GLY 41  41  41  GLY GLY D . n 
D 4 42  GLN 42  42  42  GLN GLN D . n 
D 4 43  ALA 43  43  43  ALA ALA D . n 
D 4 44  PRO 44  44  44  PRO PRO D . n 
D 4 45  ARG 45  45  45  ARG ARG D . n 
D 4 46  LEU 46  46  46  LEU LEU D . n 
D 4 47  LEU 47  47  47  LEU LEU D . n 
D 4 48  ILE 48  48  48  ILE ILE D . n 
D 4 49  TYR 49  49  49  TYR TYR D . n 
D 4 50  GLY 50  50  50  GLY GLY D . n 
D 4 51  ALA 51  51  51  ALA ALA D . n 
D 4 52  SER 52  52  52  SER SER D . n 
D 4 53  SER 53  53  53  SER SER D . n 
D 4 54  ARG 54  54  54  ARG ARG D . n 
D 4 55  ALA 55  55  55  ALA ALA D . n 
D 4 56  THR 56  56  56  THR THR D . n 
D 4 57  GLY 57  57  57  GLY GLY D . n 
D 4 58  ILE 58  58  58  ILE ILE D . n 
D 4 59  PRO 59  59  59  PRO PRO D . n 
D 4 60  ASP 60  60  60  ASP ASP D . n 
D 4 61  ARG 61  61  61  ARG ARG D . n 
D 4 62  PHE 62  62  62  PHE PHE D . n 
D 4 63  SER 63  63  63  SER SER D . n 
D 4 64  GLY 64  64  64  GLY GLY D . n 
D 4 65  SER 65  65  65  SER SER D . n 
D 4 66  GLY 66  66  66  GLY GLY D . n 
D 4 67  SER 67  67  67  SER SER D . n 
D 4 68  GLY 68  68  68  GLY GLY D . n 
D 4 69  THR 69  69  69  THR THR D . n 
D 4 70  ASP 70  70  70  ASP ASP D . n 
D 4 71  PHE 71  71  71  PHE PHE D . n 
D 4 72  THR 72  72  72  THR THR D . n 
D 4 73  LEU 73  73  73  LEU LEU D . n 
D 4 74  THR 74  74  74  THR THR D . n 
D 4 75  ILE 75  75  75  ILE ILE D . n 
D 4 76  SER 76  76  76  SER SER D . n 
D 4 77  ARG 77  77  77  ARG ARG D . n 
D 4 78  LEU 78  78  78  LEU LEU D . n 
D 4 79  GLU 79  79  79  GLU GLU D . n 
D 4 80  PRO 80  80  80  PRO PRO D . n 
D 4 81  GLU 81  81  81  GLU GLU D . n 
D 4 82  ASP 82  82  82  ASP ASP D . n 
D 4 83  PHE 83  83  83  PHE PHE D . n 
D 4 84  ALA 84  84  84  ALA ALA D . n 
D 4 85  VAL 85  85  85  VAL VAL D . n 
D 4 86  TYR 86  86  86  TYR TYR D . n 
D 4 87  TYR 87  87  87  TYR TYR D . n 
D 4 88  CYS 88  88  88  CYS CYS D . n 
D 4 89  GLN 89  89  89  GLN GLN D . n 
D 4 90  GLN 90  90  90  GLN GLN D . n 
D 4 91  TYR 91  91  91  TYR TYR D . n 
D 4 92  GLY 92  92  92  GLY GLY D . n 
D 4 93  SER 93  93  93  SER SER D . n 
D 4 94  SER 94  94  94  SER SER D . n 
D 4 95  PRO 95  95  95  PRO PRO D . n 
D 4 96  ARG 96  96  96  ARG ARG D . n 
D 4 97  THR 97  97  97  THR THR D . n 
D 4 98  PHE 98  98  98  PHE PHE D . n 
D 4 99  GLY 99  99  99  GLY GLY D . n 
D 4 100 GLN 100 100 100 GLN GLN D . n 
D 4 101 GLY 101 101 101 GLY GLY D . n 
D 4 102 THR 102 102 102 THR THR D . n 
D 4 103 LYS 103 103 103 LYS LYS D . n 
D 4 104 LEU 104 104 104 LEU LEU D . n 
D 4 105 GLU 105 105 105 GLU GLU D . n 
D 4 106 ILE 106 106 106 ILE ILE D . n 
D 4 107 LYS 107 107 107 LYS LYS D . n 
D 4 108 ARG 108 108 108 ARG ARG D . n 
D 4 109 THR 109 109 109 THR THR D . n 
D 4 110 VAL 110 110 110 VAL VAL D . n 
D 4 111 ALA 111 111 111 ALA ALA D . n 
D 4 112 ALA 112 112 112 ALA ALA D . n 
D 4 113 PRO 113 113 113 PRO PRO D . n 
D 4 114 SER 114 114 114 SER SER D . n 
D 4 115 VAL 115 115 115 VAL VAL D . n 
D 4 116 PHE 116 116 116 PHE PHE D . n 
D 4 117 ILE 117 117 117 ILE ILE D . n 
D 4 118 PHE 118 118 118 PHE PHE D . n 
D 4 119 PRO 119 119 119 PRO PRO D . n 
D 4 120 PRO 120 120 120 PRO PRO D . n 
D 4 121 SER 121 121 121 SER SER D . n 
D 4 122 ASP 122 122 122 ASP ASP D . n 
D 4 123 GLU 123 123 123 GLU GLU D . n 
D 4 124 GLN 124 124 124 GLN GLN D . n 
D 4 125 LEU 125 125 125 LEU LEU D . n 
D 4 126 LYS 126 126 126 LYS LYS D . n 
D 4 127 SER 127 127 127 SER SER D . n 
D 4 128 GLY 128 128 128 GLY GLY D . n 
D 4 129 THR 129 129 129 THR THR D . n 
D 4 130 ALA 130 130 130 ALA ALA D . n 
D 4 131 SER 131 131 131 SER SER D . n 
D 4 132 VAL 132 132 132 VAL VAL D . n 
D 4 133 VAL 133 133 133 VAL VAL D . n 
D 4 134 CYS 134 134 134 CYS CYS D . n 
D 4 135 LEU 135 135 135 LEU LEU D . n 
D 4 136 LEU 136 136 136 LEU LEU D . n 
D 4 137 ASN 137 137 137 ASN ASN D . n 
D 4 138 ASN 138 138 138 ASN ASN D . n 
D 4 139 PHE 139 139 139 PHE PHE D . n 
D 4 140 TYR 140 140 140 TYR TYR D . n 
D 4 141 PRO 141 141 141 PRO PRO D . n 
D 4 142 ARG 142 142 142 ARG ARG D . n 
D 4 143 GLU 143 143 143 GLU GLU D . n 
D 4 144 ALA 144 144 144 ALA ALA D . n 
D 4 145 LYS 145 145 145 LYS LYS D . n 
D 4 146 VAL 146 146 146 VAL VAL D . n 
D 4 147 GLN 147 147 147 GLN GLN D . n 
D 4 148 TRP 148 148 148 TRP TRP D . n 
D 4 149 LYS 149 149 149 LYS LYS D . n 
D 4 150 VAL 150 150 150 VAL VAL D . n 
D 4 151 ASP 151 151 151 ASP ASP D . n 
D 4 152 ASN 152 152 152 ASN ASN D . n 
D 4 153 ALA 153 153 153 ALA ALA D . n 
D 4 154 LEU 154 154 154 LEU LEU D . n 
D 4 155 GLN 155 155 155 GLN GLN D . n 
D 4 156 SER 156 156 156 SER SER D . n 
D 4 157 GLY 157 157 157 GLY GLY D . n 
D 4 158 ASN 158 158 158 ASN ASN D . n 
D 4 159 SER 159 159 159 SER SER D . n 
D 4 160 GLN 160 160 160 GLN GLN D . n 
D 4 161 GLU 161 161 161 GLU GLU D . n 
D 4 162 SER 162 162 162 SER SER D . n 
D 4 163 VAL 163 163 163 VAL VAL D . n 
D 4 164 THR 164 164 164 THR THR D . n 
D 4 165 GLU 165 165 165 GLU GLU D . n 
D 4 166 GLN 166 166 166 GLN GLN D . n 
D 4 167 ASP 167 167 167 ASP ASP D . n 
D 4 168 SER 168 168 168 SER SER D . n 
D 4 169 LYS 169 169 169 LYS LYS D . n 
D 4 170 ASP 170 170 170 ASP ASP D . n 
D 4 171 SER 171 171 171 SER SER D . n 
D 4 172 THR 172 172 172 THR THR D . n 
D 4 173 TYR 173 173 173 TYR TYR D . n 
D 4 174 SER 174 174 174 SER SER D . n 
D 4 175 LEU 175 175 175 LEU LEU D . n 
D 4 176 SER 176 176 176 SER SER D . n 
D 4 177 SER 177 177 177 SER SER D . n 
D 4 178 THR 178 178 178 THR THR D . n 
D 4 179 LEU 179 179 179 LEU LEU D . n 
D 4 180 THR 180 180 180 THR THR D . n 
D 4 181 LEU 181 181 181 LEU LEU D . n 
D 4 182 SER 182 182 182 SER SER D . n 
D 4 183 LYS 183 183 183 LYS LYS D . n 
D 4 184 ALA 184 184 184 ALA ALA D . n 
D 4 185 ASP 185 185 185 ASP ASP D . n 
D 4 186 TYR 186 186 186 TYR TYR D . n 
D 4 187 GLU 187 187 187 GLU GLU D . n 
D 4 188 LYS 188 188 188 LYS LYS D . n 
D 4 189 HIS 189 189 189 HIS HIS D . n 
D 4 190 LYS 190 190 190 LYS LYS D . n 
D 4 191 VAL 191 191 191 VAL VAL D . n 
D 4 192 TYR 192 192 192 TYR TYR D . n 
D 4 193 ALA 193 193 193 ALA ALA D . n 
D 4 194 CYS 194 194 194 CYS CYS D . n 
D 4 195 GLU 195 195 195 GLU GLU D . n 
D 4 196 VAL 196 196 196 VAL VAL D . n 
D 4 197 THR 197 197 197 THR THR D . n 
D 4 198 HIS 198 198 198 HIS HIS D . n 
D 4 199 GLN 199 199 199 GLN GLN D . n 
D 4 200 GLY 200 200 200 GLY GLY D . n 
D 4 201 LEU 201 201 201 LEU LEU D . n 
D 4 202 SER 202 202 202 SER SER D . n 
D 4 203 SER 203 203 203 SER SER D . n 
D 4 204 PRO 204 204 204 PRO PRO D . n 
D 4 205 VAL 205 205 205 VAL VAL D . n 
D 4 206 THR 206 206 206 THR THR D . n 
D 4 207 LYS 207 207 207 LYS LYS D . n 
D 4 208 SER 208 208 208 SER SER D . n 
D 4 209 PHE 209 209 209 PHE PHE D . n 
D 4 210 ASN 210 210 210 ASN ASN D . n 
D 4 211 ARG 211 211 211 ARG ARG D . n 
D 4 212 GLY 212 212 212 GLY GLY D . n 
D 4 213 GLU 213 213 ?   ?   ?   D . n 
D 4 214 CYS 214 214 ?   ?   ?   D . n 
E 5 1   THR 1   333 ?   ?   ?   A . n 
E 5 2   ASN 2   334 334 ASN ASN A . n 
E 5 3   LEU 3   335 335 LEU LEU A . n 
E 5 4   CYS 4   336 336 CYS CYS A . n 
E 5 5   PRO 5   337 337 PRO PRO A . n 
E 5 6   PHE 6   338 338 PHE PHE A . n 
E 5 7   GLY 7   339 339 GLY GLY A . n 
E 5 8   GLU 8   340 340 GLU GLU A . n 
E 5 9   VAL 9   341 341 VAL VAL A . n 
E 5 10  PHE 10  342 342 PHE PHE A . n 
E 5 11  ASN 11  343 343 ASN ASN A . n 
E 5 12  ALA 12  344 344 ALA ALA A . n 
E 5 13  THR 13  345 345 THR THR A . n 
E 5 14  ARG 14  346 346 ARG ARG A . n 
E 5 15  PHE 15  347 347 PHE PHE A . n 
E 5 16  ALA 16  348 348 ALA ALA A . n 
E 5 17  SER 17  349 349 SER SER A . n 
E 5 18  VAL 18  350 350 VAL VAL A . n 
E 5 19  TYR 19  351 351 TYR TYR A . n 
E 5 20  ALA 20  352 352 ALA ALA A . n 
E 5 21  TRP 21  353 353 TRP TRP A . n 
E 5 22  ASN 22  354 354 ASN ASN A . n 
E 5 23  ARG 23  355 355 ARG ARG A . n 
E 5 24  LYS 24  356 356 LYS LYS A . n 
E 5 25  ARG 25  357 357 ARG ARG A . n 
E 5 26  ILE 26  358 358 ILE ILE A . n 
E 5 27  SER 27  359 359 SER SER A . n 
E 5 28  ASN 28  360 360 ASN ASN A . n 
E 5 29  CYS 29  361 361 CYS CYS A . n 
E 5 30  VAL 30  362 362 VAL VAL A . n 
E 5 31  ALA 31  363 363 ALA ALA A . n 
E 5 32  ASP 32  364 364 ASP ASP A . n 
E 5 33  TYR 33  365 365 TYR TYR A . n 
E 5 34  SER 34  366 366 SER SER A . n 
E 5 35  VAL 35  367 367 VAL VAL A . n 
E 5 36  LEU 36  368 368 LEU LEU A . n 
E 5 37  TYR 37  369 369 TYR TYR A . n 
E 5 38  ASN 38  370 370 ASN ASN A . n 
E 5 39  SER 39  371 371 SER SER A . n 
E 5 40  ALA 40  372 372 ALA ALA A . n 
E 5 41  SER 41  373 373 SER SER A . n 
E 5 42  PHE 42  374 374 PHE PHE A . n 
E 5 43  SER 43  375 375 SER SER A . n 
E 5 44  THR 44  376 376 THR THR A . n 
E 5 45  PHE 45  377 377 PHE PHE A . n 
E 5 46  LYS 46  378 378 LYS LYS A . n 
E 5 47  CYS 47  379 379 CYS CYS A . n 
E 5 48  TYR 48  380 380 TYR TYR A . n 
E 5 49  GLY 49  381 381 GLY GLY A . n 
E 5 50  VAL 50  382 382 VAL VAL A . n 
E 5 51  SER 51  383 383 SER SER A . n 
E 5 52  PRO 52  384 384 PRO PRO A . n 
E 5 53  THR 53  385 385 THR THR A . n 
E 5 54  LYS 54  386 386 LYS LYS A . n 
E 5 55  LEU 55  387 387 LEU LEU A . n 
E 5 56  ASN 56  388 388 ASN ASN A . n 
E 5 57  ASP 57  389 389 ASP ASP A . n 
E 5 58  LEU 58  390 390 LEU LEU A . n 
E 5 59  CYS 59  391 391 CYS CYS A . n 
E 5 60  PHE 60  392 392 PHE PHE A . n 
E 5 61  THR 61  393 393 THR THR A . n 
E 5 62  ASN 62  394 394 ASN ASN A . n 
E 5 63  VAL 63  395 395 VAL VAL A . n 
E 5 64  TYR 64  396 396 TYR TYR A . n 
E 5 65  ALA 65  397 397 ALA ALA A . n 
E 5 66  ASP 66  398 398 ASP ASP A . n 
E 5 67  SER 67  399 399 SER SER A . n 
E 5 68  PHE 68  400 400 PHE PHE A . n 
E 5 69  VAL 69  401 401 VAL VAL A . n 
E 5 70  ILE 70  402 402 ILE ILE A . n 
E 5 71  ARG 71  403 403 ARG ARG A . n 
E 5 72  GLY 72  404 404 GLY GLY A . n 
E 5 73  ASP 73  405 405 ASP ASP A . n 
E 5 74  GLU 74  406 406 GLU GLU A . n 
E 5 75  VAL 75  407 407 VAL VAL A . n 
E 5 76  ARG 76  408 408 ARG ARG A . n 
E 5 77  GLN 77  409 409 GLN GLN A . n 
E 5 78  ILE 78  410 410 ILE ILE A . n 
E 5 79  ALA 79  411 411 ALA ALA A . n 
E 5 80  PRO 80  412 412 PRO PRO A . n 
E 5 81  GLY 81  413 413 GLY GLY A . n 
E 5 82  GLN 82  414 414 GLN GLN A . n 
E 5 83  THR 83  415 415 THR THR A . n 
E 5 84  GLY 84  416 416 GLY GLY A . n 
E 5 85  LYS 85  417 417 LYS LYS A . n 
E 5 86  ILE 86  418 418 ILE ILE A . n 
E 5 87  ALA 87  419 419 ALA ALA A . n 
E 5 88  ASP 88  420 420 ASP ASP A . n 
E 5 89  TYR 89  421 421 TYR TYR A . n 
E 5 90  ASN 90  422 422 ASN ASN A . n 
E 5 91  TYR 91  423 423 TYR TYR A . n 
E 5 92  LYS 92  424 424 LYS LYS A . n 
E 5 93  LEU 93  425 425 LEU LEU A . n 
E 5 94  PRO 94  426 426 PRO PRO A . n 
E 5 95  ASP 95  427 427 ASP ASP A . n 
E 5 96  ASP 96  428 428 ASP ASP A . n 
E 5 97  PHE 97  429 429 PHE PHE A . n 
E 5 98  THR 98  430 430 THR THR A . n 
E 5 99  GLY 99  431 431 GLY GLY A . n 
E 5 100 CYS 100 432 432 CYS CYS A . n 
E 5 101 VAL 101 433 433 VAL VAL A . n 
E 5 102 ILE 102 434 434 ILE ILE A . n 
E 5 103 ALA 103 435 435 ALA ALA A . n 
E 5 104 TRP 104 436 436 TRP TRP A . n 
E 5 105 ASN 105 437 437 ASN ASN A . n 
E 5 106 SER 106 438 438 SER SER A . n 
E 5 107 ASN 107 439 439 ASN ASN A . n 
E 5 108 ASN 108 440 440 ASN ASN A . n 
E 5 109 LEU 109 441 441 LEU LEU A . n 
E 5 110 ASP 110 442 442 ASP ASP A . n 
E 5 111 SER 111 443 443 SER SER A . n 
E 5 112 LYS 112 444 444 LYS LYS A . n 
E 5 113 VAL 113 445 445 VAL VAL A . n 
E 5 114 GLY 114 446 446 GLY GLY A . n 
E 5 115 GLY 115 447 447 GLY GLY A . n 
E 5 116 ASN 116 448 448 ASN ASN A . n 
E 5 117 TYR 117 449 449 TYR TYR A . n 
E 5 118 ASN 118 450 450 ASN ASN A . n 
E 5 119 TYR 119 451 451 TYR TYR A . n 
E 5 120 LEU 120 452 452 LEU LEU A . n 
E 5 121 TYR 121 453 453 TYR TYR A . n 
E 5 122 ARG 122 454 454 ARG ARG A . n 
E 5 123 LEU 123 455 455 LEU LEU A . n 
E 5 124 PHE 124 456 456 PHE PHE A . n 
E 5 125 ARG 125 457 457 ARG ARG A . n 
E 5 126 LYS 126 458 458 LYS LYS A . n 
E 5 127 SER 127 459 459 SER SER A . n 
E 5 128 ASN 128 460 460 ASN ASN A . n 
E 5 129 LEU 129 461 461 LEU LEU A . n 
E 5 130 LYS 130 462 462 LYS LYS A . n 
E 5 131 PRO 131 463 463 PRO PRO A . n 
E 5 132 PHE 132 464 464 PHE PHE A . n 
E 5 133 GLU 133 465 465 GLU GLU A . n 
E 5 134 ARG 134 466 466 ARG ARG A . n 
E 5 135 ASP 135 467 467 ASP ASP A . n 
E 5 136 ILE 136 468 468 ILE ILE A . n 
E 5 137 SER 137 469 469 SER SER A . n 
E 5 138 THR 138 470 470 THR THR A . n 
E 5 139 GLU 139 471 471 GLU GLU A . n 
E 5 140 ILE 140 472 472 ILE ILE A . n 
E 5 141 TYR 141 473 473 TYR TYR A . n 
E 5 142 GLN 142 474 474 GLN GLN A . n 
E 5 143 ALA 143 475 475 ALA ALA A . n 
E 5 144 GLY 144 476 476 GLY GLY A . n 
E 5 145 SER 145 477 477 SER SER A . n 
E 5 146 THR 146 478 478 THR THR A . n 
E 5 147 PRO 147 479 479 PRO PRO A . n 
E 5 148 CYS 148 480 480 CYS CYS A . n 
E 5 149 ASN 149 481 481 ASN ASN A . n 
E 5 150 GLY 150 482 482 GLY GLY A . n 
E 5 151 VAL 151 483 483 VAL VAL A . n 
E 5 152 GLU 152 484 484 GLU GLU A . n 
E 5 153 GLY 153 485 485 GLY GLY A . n 
E 5 154 PHE 154 486 486 PHE PHE A . n 
E 5 155 ASN 155 487 487 ASN ASN A . n 
E 5 156 CYS 156 488 488 CYS CYS A . n 
E 5 157 TYR 157 489 489 TYR TYR A . n 
E 5 158 PHE 158 490 490 PHE PHE A . n 
E 5 159 PRO 159 491 491 PRO PRO A . n 
E 5 160 LEU 160 492 492 LEU LEU A . n 
E 5 161 GLN 161 493 493 GLN GLN A . n 
E 5 162 SER 162 494 494 SER SER A . n 
E 5 163 TYR 163 495 495 TYR TYR A . n 
E 5 164 GLY 164 496 496 GLY GLY A . n 
E 5 165 PHE 165 497 497 PHE PHE A . n 
E 5 166 GLN 166 498 498 GLN GLN A . n 
E 5 167 PRO 167 499 499 PRO PRO A . n 
E 5 168 THR 168 500 500 THR THR A . n 
E 5 169 ASN 169 501 501 ASN ASN A . n 
E 5 170 GLY 170 502 502 GLY GLY A . n 
E 5 171 VAL 171 503 503 VAL VAL A . n 
E 5 172 GLY 172 504 504 GLY GLY A . n 
E 5 173 TYR 173 505 505 TYR TYR A . n 
E 5 174 GLN 174 506 506 GLN GLN A . n 
E 5 175 PRO 175 507 507 PRO PRO A . n 
E 5 176 TYR 176 508 508 TYR TYR A . n 
E 5 177 ARG 177 509 509 ARG ARG A . n 
E 5 178 VAL 178 510 510 VAL VAL A . n 
E 5 179 VAL 179 511 511 VAL VAL A . n 
E 5 180 VAL 180 512 512 VAL VAL A . n 
E 5 181 LEU 181 513 513 LEU LEU A . n 
E 5 182 SER 182 514 514 SER SER A . n 
E 5 183 PHE 183 515 515 PHE PHE A . n 
E 5 184 GLU 184 516 516 GLU GLU A . n 
E 5 185 LEU 185 517 517 LEU LEU A . n 
E 5 186 LEU 186 518 518 LEU LEU A . n 
E 5 187 HIS 187 519 519 HIS HIS A . n 
E 5 188 ALA 188 520 520 ALA ALA A . n 
E 5 189 PRO 189 521 521 PRO PRO A . n 
E 5 190 ALA 190 522 522 ALA ALA A . n 
E 5 191 THR 191 523 523 THR THR A . n 
E 5 192 VAL 192 524 524 VAL VAL A . n 
E 5 193 CYS 193 525 525 CYS CYS A . n 
E 5 194 GLY 194 526 526 GLY GLY A . n 
E 5 195 PRO 195 527 527 PRO PRO A . n 
E 5 196 LYS 196 528 ?   ?   ?   A . n 
E 5 197 LYS 197 529 ?   ?   ?   A . n 
E 5 198 SER 198 530 ?   ?   ?   A . n 
E 5 199 GLY 199 531 ?   ?   ?   A . n 
E 5 200 HIS 200 532 ?   ?   ?   A . n 
E 5 201 HIS 201 533 ?   ?   ?   A . n 
E 5 202 HIS 202 534 ?   ?   ?   A . n 
E 5 203 HIS 203 535 ?   ?   ?   A . n 
E 5 204 HIS 204 536 ?   ?   ?   A . n 
E 5 205 HIS 205 537 ?   ?   ?   A . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
F 6 NAG 1 B NAG 1 B NAG 1 n 
F 6 NAG 2 B NAG 2 B NAG 2 n 
F 6 BMA 3 B BMA 3 B BMA 3 n 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.21rc1_5127: ???)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                     2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                     3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .                     4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CPV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     110.538 
_cell.length_a_esd                 ? 
_cell.length_b                     110.538 
_cell.length_b_esd                 ? 
_cell.length_c                     224.937 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CPV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                92 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 41 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CPV 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.92 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          57.89 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M sodium citrate / citric acid, pH 4.33, 25% v/v PEG200, 6% w/v PEG6000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-04-18 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97946 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97946 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9CPV 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.00 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     28903 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                12.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.968 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.109 
_reflns.pdbx_Rpim_I_all                                0.030 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.0 
_reflns.pdbx_CC_star                                   1.0 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.105 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
3.00 3.05  ? ? ? ? ? ? 1416 ? ? ? ? ? ? ? ? ? ? ? 12.6 0.825 ? ? 1.328 0.370 ? 1  1 0.743 0.923 ? 100.0 ? 1.274 ? ? ? ? ? ? ? ? ? 
3.05 3.11  ? ? ? ? ? ? 1394 ? ? ? ? ? ? ? ? ? ? ? 12.6 0.832 ? ? 1.104 0.309 ? 2  1 0.794 0.941 ? 100.0 ? 1.059 ? ? ? ? ? ? ? ? ? 
3.11 3.17  ? ? ? ? ? ? 1435 ? ? ? ? ? ? ? ? ? ? ? 12.4 0.855 ? ? 0.904 0.254 ? 3  1 0.852 0.959 ? 100.0 ? 0.867 ? ? ? ? ? ? ? ? ? 
3.17 3.23  ? ? ? ? ? ? 1392 ? ? ? ? ? ? ? ? ? ? ? 12.4 0.873 ? ? 0.737 0.208 ? 4  1 0.892 0.971 ? 99.9  ? 0.707 ? ? ? ? ? ? ? ? ? 
3.23 3.30  ? ? ? ? ? ? 1439 ? ? ? ? ? ? ? ? ? ? ? 12.2 0.885 ? ? 0.605 0.172 ? 5  1 0.915 0.978 ? 99.9  ? 0.580 ? ? ? ? ? ? ? ? ? 
3.30 3.38  ? ? ? ? ? ? 1405 ? ? ? ? ? ? ? ? ? ? ? 12.0 0.903 ? ? 0.483 0.138 ? 6  1 0.938 0.984 ? 100.0 ? 0.463 ? ? ? ? ? ? ? ? ? 
3.38 3.46  ? ? ? ? ? ? 1433 ? ? ? ? ? ? ? ? ? ? ? 11.7 1.045 ? ? 0.388 0.112 ? 7  1 0.954 0.988 ? 100.0 ? 0.371 ? ? ? ? ? ? ? ? ? 
3.46 3.56  ? ? ? ? ? ? 1425 ? ? ? ? ? ? ? ? ? ? ? 11.1 0.984 ? ? 0.308 0.092 ? 8  1 0.973 0.993 ? 100.0 ? 0.294 ? ? ? ? ? ? ? ? ? 
3.56 3.66  ? ? ? ? ? ? 1409 ? ? ? ? ? ? ? ? ? ? ? 9.7  1.031 ? ? 0.248 0.079 ? 9  1 0.978 0.994 ? 100.0 ? 0.235 ? ? ? ? ? ? ? ? ? 
3.66 3.78  ? ? ? ? ? ? 1413 ? ? ? ? ? ? ? ? ? ? ? 11.8 1.023 ? ? 0.225 0.065 ? 10 1 0.984 0.996 ? 100.0 ? 0.215 ? ? ? ? ? ? ? ? ? 
3.78 3.91  ? ? ? ? ? ? 1462 ? ? ? ? ? ? ? ? ? ? ? 13.0 1.068 ? ? 0.190 0.052 ? 11 1 0.990 0.998 ? 100.0 ? 0.182 ? ? ? ? ? ? ? ? ? 
3.91 4.07  ? ? ? ? ? ? 1419 ? ? ? ? ? ? ? ? ? ? ? 13.3 1.083 ? ? 0.153 0.042 ? 12 1 0.993 0.998 ? 100.0 ? 0.148 ? ? ? ? ? ? ? ? ? 
4.07 4.26  ? ? ? ? ? ? 1453 ? ? ? ? ? ? ? ? ? ? ? 13.4 1.084 ? ? 0.118 0.032 ? 13 1 0.995 0.999 ? 100.0 ? 0.114 ? ? ? ? ? ? ? ? ? 
4.26 4.48  ? ? ? ? ? ? 1437 ? ? ? ? ? ? ? ? ? ? ? 13.8 1.166 ? ? 0.097 0.026 ? 14 1 0.996 0.999 ? 100.0 ? 0.094 ? ? ? ? ? ? ? ? ? 
4.48 4.76  ? ? ? ? ? ? 1436 ? ? ? ? ? ? ? ? ? ? ? 14.0 1.143 ? ? 0.081 0.021 ? 15 1 0.998 0.999 ? 99.6  ? 0.078 ? ? ? ? ? ? ? ? ? 
4.76 5.13  ? ? ? ? ? ? 1450 ? ? ? ? ? ? ? ? ? ? ? 14.4 1.067 ? ? 0.073 0.019 ? 16 1 0.998 0.999 ? 99.9  ? 0.071 ? ? ? ? ? ? ? ? ? 
5.13 5.64  ? ? ? ? ? ? 1473 ? ? ? ? ? ? ? ? ? ? ? 14.3 0.983 ? ? 0.068 0.018 ? 17 1 0.998 0.999 ? 99.9  ? 0.065 ? ? ? ? ? ? ? ? ? 
5.64 6.46  ? ? ? ? ? ? 1481 ? ? ? ? ? ? ? ? ? ? ? 13.6 0.914 ? ? 0.063 0.017 ? 18 1 0.998 0.999 ? 99.7  ? 0.060 ? ? ? ? ? ? ? ? ? 
6.46 8.13  ? ? ? ? ? ? 1508 ? ? ? ? ? ? ? ? ? ? ? 12.3 0.839 ? ? 0.049 0.014 ? 19 1 0.999 1.000 ? 99.9  ? 0.047 ? ? ? ? ? ? ? ? ? 
8.13 50.00 ? ? ? ? ? ? 1623 ? ? ? ? ? ? ? ? ? ? ? 12.8 0.726 ? ? 0.037 0.010 ? 20 1 0.999 1.000 ? 99.3  ? 0.035 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CPV 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.00 
_refine.ls_d_res_low                             49.60 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     27562 
_refine.ls_number_reflns_R_free                  2000 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.54 
_refine.ls_percent_reflns_R_free                 7.26 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2113 
_refine.ls_R_factor_R_free                       0.2617 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2074 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 25.04 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.38 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.00 
_refine_hist.d_res_low                        49.60 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               8108 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8069 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         39 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.002  ? ?    ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.523  ? ?    ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 15.010 ? 2953 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.042  ? 1260 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.004  ? 1444 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.00 3.07  . . 104 1332 70.00  . . . . 0.3194 . . . . . . . . . . . 0.4117 
'X-RAY DIFFRACTION' 3.07 3.15  . . 117 1488 80.00  . . . . 0.2820 . . . . . . . . . . . 0.3275 
'X-RAY DIFFRACTION' 3.15 3.25  . . 132 1697 91.00  . . . . 0.2679 . . . . . . . . . . . 0.3577 
'X-RAY DIFFRACTION' 3.25 3.35  . . 143 1827 97.00  . . . . 0.2595 . . . . . . . . . . . 0.3049 
'X-RAY DIFFRACTION' 3.35 3.47  . . 147 1871 100.00 . . . . 0.2542 . . . . . . . . . . . 0.3330 
'X-RAY DIFFRACTION' 3.47 3.61  . . 145 1857 100.00 . . . . 0.2227 . . . . . . . . . . . 0.2915 
'X-RAY DIFFRACTION' 3.61 3.77  . . 148 1884 100.00 . . . . 0.2241 . . . . . . . . . . . 0.2704 
'X-RAY DIFFRACTION' 3.77 3.97  . . 148 1908 100.00 . . . . 0.2114 . . . . . . . . . . . 0.2881 
'X-RAY DIFFRACTION' 3.97 4.22  . . 149 1893 100.00 . . . . 0.1925 . . . . . . . . . . . 0.2557 
'X-RAY DIFFRACTION' 4.22 4.55  . . 149 1906 100.00 . . . . 0.1731 . . . . . . . . . . . 0.2442 
'X-RAY DIFFRACTION' 4.55 5.01  . . 151 1920 100.00 . . . . 0.1656 . . . . . . . . . . . 0.1905 
'X-RAY DIFFRACTION' 5.01 5.73  . . 149 1925 100.00 . . . . 0.1792 . . . . . . . . . . . 0.2298 
'X-RAY DIFFRACTION' 5.73 7.21  . . 155 1967 100.00 . . . . 0.2092 . . . . . . . . . . . 0.2652 
'X-RAY DIFFRACTION' 7.21 49.60 . . 163 2087 99.00  . . . . 0.1820 . . . . . . . . . . . 0.2070 
# 
_struct.entry_id                     9CPV 
_struct.title                        
'Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0614 and CC12.3' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CPV 
_struct_keywords.text            'COVID-19, SARS-CoV-2, Receptor binding domain, Antibody, VIRAL PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9CPV        9CPV   ? 1 ? 1   
2 PDB 9CPV        9CPV   ? 2 ? 1   
3 PDB 9CPV        9CPV   ? 3 ? 1   
4 PDB 9CPV        9CPV   ? 4 ? 1   
5 UNP SPIKE_SARS2 P0DTC2 ? 5 
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKS
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CPV H 1 ? 222 ? 9CPV   1   ? 216 ? 1   216 
2 2 9CPV L 1 ? 220 ? 9CPV   1   ? 214 ? 1   214 
3 3 9CPV C 1 ? 220 ? 9CPV   1   ? 216 ? 1   216 
4 4 9CPV D 1 ? 214 ? 9CPV   1   ? 214 ? 1   214 
5 5 9CPV A 1 ? 198 ? P0DTC2 333 ? 530 ? 333 530 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
5 9CPV GLY A 199 ? UNP P0DTC2 ? ? 'expression tag' 531 1 
5 9CPV HIS A 200 ? UNP P0DTC2 ? ? 'expression tag' 532 2 
5 9CPV HIS A 201 ? UNP P0DTC2 ? ? 'expression tag' 533 3 
5 9CPV HIS A 202 ? UNP P0DTC2 ? ? 'expression tag' 534 4 
5 9CPV HIS A 203 ? UNP P0DTC2 ? ? 'expression tag' 535 5 
5 9CPV HIS A 204 ? UNP P0DTC2 ? ? 'expression tag' 536 6 
5 9CPV HIS A 205 ? UNP P0DTC2 ? ? 'expression tag' 537 7 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 11410 ? 
1 MORE         -56   ? 
1 'SSA (A^2)'  45470 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 28  ? TYR A 32  ? SER H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2  AA2 LYS A 87  ? THR A 91  ? LYS H 83  THR H 87  5 ? 5 
HELX_P HELX_P3  AA3 SER A 133 ? THR A 137 ? SER H 127 THR H 131 5 ? 5 
HELX_P HELX_P4  AA4 PRO A 191 ? LEU A 195 ? PRO H 185 LEU H 189 5 ? 5 
HELX_P HELX_P5  AA5 LYS A 207 ? ASN A 210 ? LYS H 201 ASN H 204 5 ? 4 
HELX_P HELX_P6  AA6 GLN B 85  ? VAL B 89  ? GLN L 79  VAL L 83  5 ? 5 
HELX_P HELX_P7  AA7 SER B 127 ? SER B 133 ? SER L 121 SER L 127 1 ? 7 
HELX_P HELX_P8  AA8 LYS B 189 ? GLU B 193 ? LYS L 183 GLU L 187 1 ? 5 
HELX_P HELX_P9  AA9 ARG C 86  ? THR C 90  ? ARG C 83  THR C 87  5 ? 5 
HELX_P HELX_P10 AB1 SER C 191 ? LEU C 193 ? SER C 187 LEU C 189 5 ? 3 
HELX_P HELX_P11 AB2 LYS C 205 ? ASN C 208 ? LYS C 201 ASN C 204 5 ? 4 
HELX_P HELX_P12 AB3 SER D 121 ? SER D 127 ? SER D 121 SER D 127 1 ? 7 
HELX_P HELX_P13 AB4 LYS D 183 ? GLU D 187 ? LYS D 183 GLU D 187 1 ? 5 
HELX_P HELX_P14 AB5 PRO E 5   ? ASN E 11  ? PRO A 337 ASN A 343 1 ? 7 
HELX_P HELX_P15 AB6 SER E 17  ? TRP E 21  ? SER A 349 TRP A 353 5 ? 5 
HELX_P HELX_P16 AB7 TYR E 33  ? ASN E 38  ? TYR A 365 ASN A 370 1 ? 6 
HELX_P HELX_P17 AB8 SER E 51  ? LEU E 55  ? SER A 383 LEU A 387 5 ? 5 
HELX_P HELX_P18 AB9 GLU E 74  ? ILE E 78  ? GLU A 406 ILE A 410 5 ? 5 
HELX_P HELX_P19 AC1 GLY E 84  ? ASN E 90  ? GLY A 416 ASN A 422 1 ? 7 
HELX_P HELX_P20 AC2 SER E 106 ? SER E 111 ? SER A 438 SER A 443 1 ? 6 
HELX_P HELX_P21 AC3 GLY E 170 ? TYR E 173 ? GLY A 502 TYR A 505 5 ? 4 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 22  SG  ? ? ? 1_555 A CYS 96  SG ? ? H CYS 22  H CYS 92  1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf2  disulf ?    ? A CYS 146 SG  ? ? ? 1_555 A CYS 202 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf3  disulf ?    ? B CYS 23  SG  ? ? ? 1_555 B CYS 94  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf4  disulf ?    ? B CYS 140 SG  ? ? ? 1_555 B CYS 200 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf5  disulf ?    ? C CYS 22  SG  ? ? ? 1_555 C CYS 95  SG ? ? C CYS 22  C CYS 92  1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf6  disulf ?    ? C CYS 144 SG  ? ? ? 1_555 C CYS 200 SG ? ? C CYS 140 C CYS 196 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf7  disulf ?    ? D CYS 23  SG  ? ? ? 1_555 D CYS 88  SG ? ? D CYS 23  D CYS 88  1_555 ? ? ? ? ? ? ? 2.036 ? ?               
disulf8  disulf ?    ? D CYS 134 SG  ? ? ? 1_555 D CYS 194 SG ? ? D CYS 134 D CYS 194 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf9  disulf ?    ? E CYS 4   SG  ? ? ? 1_555 E CYS 29  SG ? ? A CYS 336 A CYS 361 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf10 disulf ?    ? E CYS 47  SG  ? ? ? 1_555 E CYS 100 SG ? ? A CYS 379 A CYS 432 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf11 disulf ?    ? E CYS 59  SG  ? ? ? 1_555 E CYS 193 SG ? ? A CYS 391 A CYS 525 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf12 disulf ?    ? E CYS 148 SG  ? ? ? 1_555 E CYS 156 SG ? ? A CYS 480 A CYS 488 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
covale1  covale one  ? E ASN 11  ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 343 B NAG 1   1_555 ? ? ? ? ? ? ? 1.447 ? N-Glycosylation 
covale2  covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? B NAG 1   B NAG 2   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale3  covale both ? F NAG .   O4  ? ? ? 1_555 F BMA .   C1 ? ? B NAG 2   B BMA 3   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG F .   ? ASN E 11  ? NAG B 1   ? 1_555 ASN A 343 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  CYS A 22  ? CYS A 96  ? CYS H 22  ? 1_555 CYS H 92  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
3  CYS A 146 ? CYS A 202 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4  CYS B 23  ? CYS B 94  ? CYS L 23  ? 1_555 CYS L 88  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS B 140 ? CYS B 200 ? CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS C 22  ? CYS C 95  ? CYS C 22  ? 1_555 CYS C 92  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS C 144 ? CYS C 200 ? CYS C 140 ? 1_555 CYS C 196 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS D 23  ? CYS D 88  ? CYS D 23  ? 1_555 CYS D 88  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS D 134 ? CYS D 194 ? CYS D 134 ? 1_555 CYS D 194 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS E 4   ? CYS E 29  ? CYS A 336 ? 1_555 CYS A 361 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS E 47  ? CYS E 100 ? CYS A 379 ? 1_555 CYS A 432 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS E 59  ? CYS E 193 ? CYS A 391 ? 1_555 CYS A 525 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS E 148 ? CYS E 156 ? CYS A 480 ? 1_555 CYS A 488 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1  PHE 152 A . ? PHE 146 H PRO 153 A ? PRO 147 H 1 -3.70 
2  GLU 154 A . ? GLU 148 H PRO 155 A ? PRO 149 H 1 -0.02 
3  SER 7   B . ? SER 7   L PRO 8   B ? PRO 8   L 1 -4.34 
4  THR 100 B . ? THR 94  L PRO 101 B ? PRO 95  L 1 -0.71 
5  TYR 146 B . ? TYR 140 L PRO 147 B ? PRO 141 L 1 2.42  
6  PHE 150 C . ? PHE 146 C PRO 151 C ? PRO 147 C 1 -3.99 
7  GLU 152 C . ? GLU 148 C PRO 153 C ? PRO 149 C 1 2.66  
8  SER 7   D . ? SER 7   D PRO 8   D ? PRO 8   D 1 -0.61 
9  SER 94  D . ? SER 94  D PRO 95  D ? PRO 95  D 1 -2.46 
10 TYR 140 D . ? TYR 140 D PRO 141 D ? PRO 141 D 1 1.93  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
AB5 ? 4 ? 
AB6 ? 4 ? 
AB7 ? 4 ? 
AB8 ? 3 ? 
AB9 ? 4 ? 
AC1 ? 2 ? 
AC2 ? 5 ? 
AC3 ? 4 ? 
AC4 ? 4 ? 
AC5 ? 5 ? 
AC6 ? 3 ? 
AC7 ? 2 ? 
AC8 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? parallel      
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC5 4 5 ? anti-parallel 
AC6 1 2 ? parallel      
AC6 2 3 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC8 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? GLN A 6   ? GLN H 3   GLN H 6   
AA1 2 LEU A 18  ? SER A 25  ? LEU H 18  SER H 25  
AA1 3 THR A 78  ? TRP A 83  ? THR H 77  TRP H 82  
AA1 4 THR A 69  ? ASP A 73  ? THR H 68  ASP H 72  
AA2 1 GLU A 10  ? LYS A 12  ? GLU H 10  LYS H 12  
AA2 2 THR A 113 ? VAL A 117 ? THR H 107 VAL H 111 
AA2 3 ALA A 92  ? GLY A 99  ? ALA H 88  GLY H 95  
AA2 4 TRP A 33  ? GLN A 39  ? TRP H 33  GLN H 39  
AA2 5 GLU A 46  ? TYR A 52  ? GLU H 46  TYR H 52  
AA2 6 ASP A 57  ? TYR A 60  ? ASP H 56  TYR H 59  
AA3 1 GLU A 10  ? LYS A 12  ? GLU H 10  LYS H 12  
AA3 2 THR A 113 ? VAL A 117 ? THR H 107 VAL H 111 
AA3 3 ALA A 92  ? GLY A 99  ? ALA H 88  GLY H 95  
AA3 4 VAL A 108 ? TRP A 109 ? VAL H 102 TRP H 103 
AA4 1 SER A 126 ? LEU A 130 ? SER H 120 LEU H 124 
AA4 2 ALA A 142 ? TYR A 151 ? ALA H 136 TYR H 145 
AA4 3 TYR A 182 ? VAL A 190 ? TYR H 176 VAL H 184 
AA4 4 HIS A 170 ? THR A 171 ? HIS H 164 THR H 165 
AA5 1 SER A 126 ? LEU A 130 ? SER H 120 LEU H 124 
AA5 2 ALA A 142 ? TYR A 151 ? ALA H 136 TYR H 145 
AA5 3 TYR A 182 ? VAL A 190 ? TYR H 176 VAL H 184 
AA5 4 VAL A 175 ? LEU A 176 ? VAL H 169 LEU H 170 
AA6 1 THR A 157 ? TRP A 160 ? THR H 151 TRP H 154 
AA6 2 TYR A 200 ? HIS A 206 ? TYR H 194 HIS H 200 
AA6 3 THR A 211 ? VAL A 217 ? THR H 205 VAL H 211 
AA7 1 LEU B 4   ? SER B 7   ? LEU L 4   SER L 7   
AA7 2 ALA B 19  ? SER B 25  ? ALA L 19  SER L 25  
AA7 3 ASP B 76  ? ILE B 81  ? ASP L 70  ILE L 75  
AA7 4 PHE B 68  ? SER B 73  ? PHE L 62  SER L 67  
AA8 1 SER B 10  ? VAL B 13  ? SER L 10  VAL L 13  
AA8 2 THR B 108 ? ILE B 112 ? THR L 102 ILE L 106 
AA8 3 VAL B 91  ? GLN B 96  ? VAL L 85  GLN L 90  
AA8 4 LEU B 39  ? GLN B 44  ? LEU L 33  GLN L 38  
AA8 5 LYS B 51  ? TYR B 55  ? LYS L 45  TYR L 49  
AA8 6 THR B 59  ? ARG B 60  ? THR L 53  ARG L 54  
AA9 1 SER B 10  ? VAL B 13  ? SER L 10  VAL L 13  
AA9 2 THR B 108 ? ILE B 112 ? THR L 102 ILE L 106 
AA9 3 VAL B 91  ? GLN B 96  ? VAL L 85  GLN L 90  
AA9 4 THR B 103 ? PHE B 104 ? THR L 97  PHE L 98  
AB1 1 SER B 120 ? PHE B 124 ? SER L 114 PHE L 118 
AB1 2 THR B 135 ? PHE B 145 ? THR L 129 PHE L 139 
AB1 3 TYR B 179 ? SER B 188 ? TYR L 173 SER L 182 
AB1 4 SER B 165 ? VAL B 169 ? SER L 159 VAL L 163 
AB2 1 ALA B 159 ? LEU B 160 ? ALA L 153 LEU L 154 
AB2 2 ALA B 150 ? VAL B 156 ? ALA L 144 VAL L 150 
AB2 3 VAL B 197 ? HIS B 204 ? VAL L 191 HIS L 198 
AB2 4 VAL B 211 ? ASN B 216 ? VAL L 205 ASN L 210 
AB3 1 GLN C 3   ? SER C 7   ? GLN C 3   SER C 7   
AB3 2 LEU C 18  ? SER C 25  ? LEU C 18  SER C 25  
AB3 3 THR C 77  ? MET C 82  ? THR C 77  MET C 82  
AB3 4 PHE C 67  ? ASP C 72  ? PHE C 67  ASP C 72  
AB4 1 LEU C 11  ? ILE C 12  ? LEU C 11  ILE C 12  
AB4 2 THR C 111 ? VAL C 115 ? THR C 107 VAL C 111 
AB4 3 ALA C 91  ? PHE C 99  ? ALA C 88  PHE C 96  
AB4 4 TYR C 33  ? GLN C 39  ? TYR C 33  GLN C 39  
AB4 5 LEU C 45  ? ILE C 51  ? LEU C 45  ILE C 51  
AB4 6 THR C 57  ? TYR C 59  ? THR C 57  TYR C 59  
AB5 1 LEU C 11  ? ILE C 12  ? LEU C 11  ILE C 12  
AB5 2 THR C 111 ? VAL C 115 ? THR C 107 VAL C 111 
AB5 3 ALA C 91  ? PHE C 99  ? ALA C 88  PHE C 96  
AB5 4 TYR C 103 ? TRP C 107 ? TYR C 100 TRP C 103 
AB6 1 SER C 124 ? LEU C 128 ? SER C 120 LEU C 124 
AB6 2 THR C 139 ? TYR C 149 ? THR C 135 TYR C 145 
AB6 3 TYR C 180 ? PRO C 189 ? TYR C 176 PRO C 185 
AB6 4 VAL C 167 ? THR C 169 ? VAL C 163 THR C 165 
AB7 1 SER C 124 ? LEU C 128 ? SER C 120 LEU C 124 
AB7 2 THR C 139 ? TYR C 149 ? THR C 135 TYR C 145 
AB7 3 TYR C 180 ? PRO C 189 ? TYR C 176 PRO C 185 
AB7 4 VAL C 173 ? LEU C 174 ? VAL C 169 LEU C 170 
AB8 1 THR C 155 ? TRP C 158 ? THR C 151 TRP C 154 
AB8 2 TYR C 198 ? HIS C 204 ? TYR C 194 HIS C 200 
AB8 3 THR C 209 ? VAL C 215 ? THR C 205 VAL C 211 
AB9 1 LEU D 4   ? SER D 7   ? LEU D 4   SER D 7   
AB9 2 ARG D 18  ? ALA D 25  ? ARG D 18  ALA D 25  
AB9 3 ASP D 70  ? SER D 76  ? ASP D 70  SER D 76  
AB9 4 PHE D 62  ? SER D 67  ? PHE D 62  SER D 67  
AC1 1 THR D 10  ? LEU D 13  ? THR D 10  LEU D 13  
AC1 2 LYS D 103 ? ILE D 106 ? LYS D 103 ILE D 106 
AC2 1 SER D 53  ? ARG D 54  ? SER D 53  ARG D 54  
AC2 2 ARG D 45  ? TYR D 49  ? ARG D 45  TYR D 49  
AC2 3 LEU D 33  ? GLN D 38  ? LEU D 33  GLN D 38  
AC2 4 VAL D 85  ? GLN D 90  ? VAL D 85  GLN D 90  
AC2 5 THR D 97  ? PHE D 98  ? THR D 97  PHE D 98  
AC3 1 SER D 114 ? PHE D 118 ? SER D 114 PHE D 118 
AC3 2 THR D 129 ? PHE D 139 ? THR D 129 PHE D 139 
AC3 3 TYR D 173 ? SER D 182 ? TYR D 173 SER D 182 
AC3 4 SER D 159 ? VAL D 163 ? SER D 159 VAL D 163 
AC4 1 ALA D 153 ? GLN D 155 ? ALA D 153 GLN D 155 
AC4 2 ALA D 144 ? VAL D 150 ? ALA D 144 VAL D 150 
AC4 3 TYR D 192 ? HIS D 198 ? TYR D 192 HIS D 198 
AC4 4 VAL D 205 ? PHE D 209 ? VAL D 205 PHE D 209 
AC5 1 ASN E 22  ? ILE E 26  ? ASN A 354 ILE A 358 
AC5 2 ASN E 62  ? ARG E 71  ? ASN A 394 ARG A 403 
AC5 3 PRO E 175 ? GLU E 184 ? PRO A 507 GLU A 516 
AC5 4 GLY E 99  ? ASN E 105 ? GLY A 431 ASN A 437 
AC5 5 THR E 44  ? TYR E 48  ? THR A 376 TYR A 380 
AC6 1 CYS E 29  ? VAL E 30  ? CYS A 361 VAL A 362 
AC6 2 VAL E 192 ? CYS E 193 ? VAL A 524 CYS A 525 
AC6 3 CYS E 59  ? PHE E 60  ? CYS A 391 PHE A 392 
AC7 1 LEU E 120 ? ARG E 122 ? LEU A 452 ARG A 454 
AC7 2 LEU E 160 ? SER E 162 ? LEU A 492 SER A 494 
AC8 1 TYR E 141 ? GLN E 142 ? TYR A 473 GLN A 474 
AC8 2 CYS E 156 ? TYR E 157 ? CYS A 488 TYR A 489 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 5   ? N VAL H 5   O LYS A 23  ? O LYS H 23  
AA1 2 3 N LEU A 18  ? N LEU H 18  O TRP A 83  ? O TRP H 82  
AA1 3 4 O THR A 78  ? O THR H 77  N ASP A 73  ? N ASP H 72  
AA2 1 2 N LYS A 12  ? N LYS H 12  O ALA A 116 ? O ALA H 110 
AA2 2 3 O THR A 113 ? O THR H 107 N TYR A 94  ? N TYR H 90  
AA2 3 4 O GLY A 99  ? O GLY H 95  N TRP A 33  ? N TRP H 33  
AA2 4 5 N ARG A 38  ? N ARG H 38  O GLU A 46  ? O GLU H 46  
AA2 5 6 N ILE A 50  ? N ILE H 50  O ARG A 59  ? O ARG H 58  
AA3 1 2 N LYS A 12  ? N LYS H 12  O ALA A 116 ? O ALA H 110 
AA3 2 3 O THR A 113 ? O THR H 107 N TYR A 94  ? N TYR H 90  
AA3 3 4 N GLY A 98  ? N GLY H 94  O VAL A 108 ? O VAL H 102 
AA4 1 2 N PHE A 128 ? N PHE H 122 O LEU A 147 ? O LEU H 141 
AA4 2 3 N VAL A 148 ? N VAL H 142 O LEU A 184 ? O LEU H 178 
AA4 3 4 O VAL A 187 ? O VAL H 181 N HIS A 170 ? N HIS H 164 
AA5 1 2 N PHE A 128 ? N PHE H 122 O LEU A 147 ? O LEU H 141 
AA5 2 3 N VAL A 148 ? N VAL H 142 O LEU A 184 ? O LEU H 178 
AA5 3 4 O SER A 183 ? O SER H 177 N VAL A 175 ? N VAL H 169 
AA6 1 2 N SER A 159 ? N SER H 153 O ASN A 203 ? O ASN H 197 
AA6 2 3 N HIS A 206 ? N HIS H 200 O THR A 211 ? O THR H 205 
AA7 1 2 N THR B 5   ? N THR L 5   O LYS B 24  ? O LYS L 24  
AA7 2 3 N CYS B 23  ? N CYS L 23  O PHE B 77  ? O PHE L 71  
AA7 3 4 O THR B 80  ? O THR L 74  N SER B 69  ? N SER L 63  
AA8 1 2 N LEU B 11  ? N LEU L 11  O LYS B 109 ? O LYS L 103 
AA8 2 3 O THR B 108 ? O THR L 102 N TYR B 92  ? N TYR L 86  
AA8 3 4 O TYR B 93  ? O TYR L 87  N TYR B 42  ? N TYR L 36  
AA8 4 5 N GLN B 43  ? N GLN L 37  O LYS B 51  ? O LYS L 45  
AA8 5 6 N TYR B 55  ? N TYR L 49  O THR B 59  ? O THR L 53  
AA9 1 2 N LEU B 11  ? N LEU L 11  O LYS B 109 ? O LYS L 103 
AA9 2 3 O THR B 108 ? O THR L 102 N TYR B 92  ? N TYR L 86  
AA9 3 4 N GLN B 96  ? N GLN L 90  O THR B 103 ? O THR L 97  
AB1 1 2 N PHE B 122 ? N PHE L 116 O LEU B 141 ? O LEU L 135 
AB1 2 3 N LEU B 142 ? N LEU L 136 O LEU B 181 ? O LEU L 175 
AB1 3 4 O THR B 184 ? O THR L 178 N GLN B 166 ? N GLN L 160 
AB2 1 2 O ALA B 159 ? O ALA L 153 N VAL B 156 ? N VAL L 150 
AB2 2 3 N LYS B 155 ? N LYS L 149 O ALA B 199 ? O ALA L 193 
AB2 3 4 N CYS B 200 ? N CYS L 194 O LYS B 213 ? O LYS L 207 
AB3 1 2 N GLN C 3   ? N GLN C 3   O SER C 25  ? O SER C 25  
AB3 2 3 N LEU C 18  ? N LEU C 18  O MET C 82  ? O MET C 82  
AB3 3 4 O TYR C 79  ? O TYR C 79  N SER C 70  ? N SER C 70  
AB4 1 2 N ILE C 12  ? N ILE C 12  O THR C 114 ? O THR C 110 
AB4 2 3 O THR C 111 ? O THR C 107 N TYR C 93  ? N TYR C 90  
AB4 3 4 O TYR C 94  ? O TYR C 91  N VAL C 37  ? N VAL C 37  
AB4 4 5 N MET C 34  ? N MET C 34  O ILE C 51  ? O ILE C 51  
AB4 5 6 N VAL C 50  ? N VAL C 50  O PHE C 58  ? O PHE C 58  
AB5 1 2 N ILE C 12  ? N ILE C 12  O THR C 114 ? O THR C 110 
AB5 2 3 O THR C 111 ? O THR C 107 N TYR C 93  ? N TYR C 90  
AB5 3 4 N PHE C 99  ? N PHE C 96  O TYR C 103 ? O TYR C 100 
AB6 1 2 N LEU C 128 ? N LEU C 124 O GLY C 143 ? O GLY C 139 
AB6 2 3 N VAL C 146 ? N VAL C 142 O LEU C 182 ? O LEU C 178 
AB6 3 4 O VAL C 185 ? O VAL C 181 N HIS C 168 ? N HIS C 164 
AB7 1 2 N LEU C 128 ? N LEU C 124 O GLY C 143 ? O GLY C 139 
AB7 2 3 N VAL C 146 ? N VAL C 142 O LEU C 182 ? O LEU C 178 
AB7 3 4 O SER C 181 ? O SER C 177 N VAL C 173 ? N VAL C 169 
AB8 1 2 N SER C 157 ? N SER C 153 O ASN C 201 ? O ASN C 197 
AB8 2 3 N HIS C 204 ? N HIS C 200 O THR C 209 ? O THR C 205 
AB9 1 2 N THR D 5   ? N THR D 5   O ARG D 24  ? O ARG D 24  
AB9 2 3 N LEU D 21  ? N LEU D 21  O LEU D 73  ? O LEU D 73  
AB9 3 4 O THR D 74  ? O THR D 74  N SER D 63  ? N SER D 63  
AC1 1 2 N LEU D 13  ? N LEU D 13  O GLU D 105 ? O GLU D 105 
AC2 1 2 O SER D 53  ? O SER D 53  N TYR D 49  ? N TYR D 49  
AC2 2 3 O ARG D 45  ? O ARG D 45  N GLN D 37  ? N GLN D 37  
AC2 3 4 N ALA D 34  ? N ALA D 34  O GLN D 89  ? O GLN D 89  
AC2 4 5 N GLN D 90  ? N GLN D 90  O THR D 97  ? O THR D 97  
AC3 1 2 N PHE D 116 ? N PHE D 116 O LEU D 135 ? O LEU D 135 
AC3 2 3 N VAL D 132 ? N VAL D 132 O LEU D 179 ? O LEU D 179 
AC3 3 4 O THR D 178 ? O THR D 178 N GLN D 160 ? N GLN D 160 
AC4 1 2 O GLN D 155 ? O GLN D 155 N TRP D 148 ? N TRP D 148 
AC4 2 3 N LYS D 149 ? N LYS D 149 O ALA D 193 ? O ALA D 193 
AC4 3 4 N VAL D 196 ? N VAL D 196 O VAL D 205 ? O VAL D 205 
AC5 1 2 N ILE E 26  ? N ILE A 358 O VAL E 63  ? O VAL A 395 
AC5 2 3 N PHE E 68  ? N PHE A 400 O VAL E 178 ? O VAL A 510 
AC5 3 4 O LEU E 181 ? O LEU A 513 N CYS E 100 ? N CYS A 432 
AC5 4 5 O GLY E 99  ? O GLY A 431 N TYR E 48  ? N TYR A 380 
AC6 1 2 N CYS E 29  ? N CYS A 361 O CYS E 193 ? O CYS A 525 
AC6 2 3 O VAL E 192 ? O VAL A 524 N PHE E 60  ? N PHE A 392 
AC7 1 2 N TYR E 121 ? N TYR A 453 O GLN E 161 ? O GLN A 493 
AC8 1 2 N TYR E 141 ? N TYR A 473 O TYR E 157 ? O TYR A 489 
# 
_pdbx_entry_details.entry_id                   9CPV 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP H 144 ? ? 60.09   65.81  
2  1 ASN H 204 ? ? 67.61   -4.79  
3  1 ALA L 51  ? ? 72.86   -6.38  
4  1 SER L 52  ? ? -143.38 -24.37 
5  1 ASP C 144 ? ? 60.45   66.76  
6  1 ALA D 51  ? ? 71.11   -4.05  
7  1 SER D 52  ? ? -131.49 -36.64 
8  1 THR D 69  ? ? -131.86 -32.51 
9  1 ASN A 360 ? ? 34.71   58.46  
10 1 ALA A 411 ? ? -171.68 149.99 
11 1 ASP A 428 ? ? -96.45  30.45  
12 1 ASN A 487 ? ? 56.00   18.89  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 H SER 215 ? A SER 221 
2  1 Y 1 H CYS 216 ? A CYS 222 
3  1 Y 1 L GLU 213 ? B GLU 219 
4  1 Y 1 L CYS 214 ? B CYS 220 
5  1 Y 1 C LYS 129 ? C LYS 133 
6  1 Y 1 C SER 130 ? C SER 134 
7  1 Y 1 C THR 131 ? C THR 135 
8  1 Y 1 C SER 132 ? C SER 136 
9  1 Y 1 C GLY 133 ? C GLY 137 
10 1 Y 1 C LEU 159 ? C LEU 163 
11 1 Y 1 C LYS 214 ? C LYS 218 
12 1 Y 1 C SER 215 ? C SER 219 
13 1 Y 1 C CYS 216 ? C CYS 220 
14 1 Y 1 D GLU 213 ? D GLU 213 
15 1 Y 1 D CYS 214 ? D CYS 214 
16 1 Y 1 A THR 333 ? E THR 1   
17 1 Y 1 A LYS 528 ? E LYS 196 
18 1 Y 1 A LYS 529 ? E LYS 197 
19 1 Y 1 A SER 530 ? E SER 198 
20 1 Y 1 A GLY 531 ? E GLY 199 
21 1 Y 1 A HIS 532 ? E HIS 200 
22 1 Y 1 A HIS 533 ? E HIS 201 
23 1 Y 1 A HIS 534 ? E HIS 202 
24 1 Y 1 A HIS 535 ? E HIS 203 
25 1 Y 1 A HIS 536 ? E HIS 204 
26 1 Y 1 A HIS 537 ? E HIS 205 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
ILE N    N N N 182 
ILE CA   C N S 183 
ILE C    C N N 184 
ILE O    O N N 185 
ILE CB   C N S 186 
ILE CG1  C N N 187 
ILE CG2  C N N 188 
ILE CD1  C N N 189 
ILE OXT  O N N 190 
ILE H    H N N 191 
ILE H2   H N N 192 
ILE HA   H N N 193 
ILE HB   H N N 194 
ILE HG12 H N N 195 
ILE HG13 H N N 196 
ILE HG21 H N N 197 
ILE HG22 H N N 198 
ILE HG23 H N N 199 
ILE HD11 H N N 200 
ILE HD12 H N N 201 
ILE HD13 H N N 202 
ILE HXT  H N N 203 
LEU N    N N N 204 
LEU CA   C N S 205 
LEU C    C N N 206 
LEU O    O N N 207 
LEU CB   C N N 208 
LEU CG   C N N 209 
LEU CD1  C N N 210 
LEU CD2  C N N 211 
LEU OXT  O N N 212 
LEU H    H N N 213 
LEU H2   H N N 214 
LEU HA   H N N 215 
LEU HB2  H N N 216 
LEU HB3  H N N 217 
LEU HG   H N N 218 
LEU HD11 H N N 219 
LEU HD12 H N N 220 
LEU HD13 H N N 221 
LEU HD21 H N N 222 
LEU HD22 H N N 223 
LEU HD23 H N N 224 
LEU HXT  H N N 225 
LYS N    N N N 226 
LYS CA   C N S 227 
LYS C    C N N 228 
LYS O    O N N 229 
LYS CB   C N N 230 
LYS CG   C N N 231 
LYS CD   C N N 232 
LYS CE   C N N 233 
LYS NZ   N N N 234 
LYS OXT  O N N 235 
LYS H    H N N 236 
LYS H2   H N N 237 
LYS HA   H N N 238 
LYS HB2  H N N 239 
LYS HB3  H N N 240 
LYS HG2  H N N 241 
LYS HG3  H N N 242 
LYS HD2  H N N 243 
LYS HD3  H N N 244 
LYS HE2  H N N 245 
LYS HE3  H N N 246 
LYS HZ1  H N N 247 
LYS HZ2  H N N 248 
LYS HZ3  H N N 249 
LYS HXT  H N N 250 
MET N    N N N 251 
MET CA   C N S 252 
MET C    C N N 253 
MET O    O N N 254 
MET CB   C N N 255 
MET CG   C N N 256 
MET SD   S N N 257 
MET CE   C N N 258 
MET OXT  O N N 259 
MET H    H N N 260 
MET H2   H N N 261 
MET HA   H N N 262 
MET HB2  H N N 263 
MET HB3  H N N 264 
MET HG2  H N N 265 
MET HG3  H N N 266 
MET HE1  H N N 267 
MET HE2  H N N 268 
MET HE3  H N N 269 
MET HXT  H N N 270 
NAG C1   C N R 271 
NAG C2   C N R 272 
NAG C3   C N R 273 
NAG C4   C N S 274 
NAG C5   C N R 275 
NAG C6   C N N 276 
NAG C7   C N N 277 
NAG C8   C N N 278 
NAG N2   N N N 279 
NAG O1   O N N 280 
NAG O3   O N N 281 
NAG O4   O N N 282 
NAG O5   O N N 283 
NAG O6   O N N 284 
NAG O7   O N N 285 
NAG H1   H N N 286 
NAG H2   H N N 287 
NAG H3   H N N 288 
NAG H4   H N N 289 
NAG H5   H N N 290 
NAG H61  H N N 291 
NAG H62  H N N 292 
NAG H81  H N N 293 
NAG H82  H N N 294 
NAG H83  H N N 295 
NAG HN2  H N N 296 
NAG HO1  H N N 297 
NAG HO3  H N N 298 
NAG HO4  H N N 299 
NAG HO6  H N N 300 
PHE N    N N N 301 
PHE CA   C N S 302 
PHE C    C N N 303 
PHE O    O N N 304 
PHE CB   C N N 305 
PHE CG   C Y N 306 
PHE CD1  C Y N 307 
PHE CD2  C Y N 308 
PHE CE1  C Y N 309 
PHE CE2  C Y N 310 
PHE CZ   C Y N 311 
PHE OXT  O N N 312 
PHE H    H N N 313 
PHE H2   H N N 314 
PHE HA   H N N 315 
PHE HB2  H N N 316 
PHE HB3  H N N 317 
PHE HD1  H N N 318 
PHE HD2  H N N 319 
PHE HE1  H N N 320 
PHE HE2  H N N 321 
PHE HZ   H N N 322 
PHE HXT  H N N 323 
PRO N    N N N 324 
PRO CA   C N S 325 
PRO C    C N N 326 
PRO O    O N N 327 
PRO CB   C N N 328 
PRO CG   C N N 329 
PRO CD   C N N 330 
PRO OXT  O N N 331 
PRO H    H N N 332 
PRO HA   H N N 333 
PRO HB2  H N N 334 
PRO HB3  H N N 335 
PRO HG2  H N N 336 
PRO HG3  H N N 337 
PRO HD2  H N N 338 
PRO HD3  H N N 339 
PRO HXT  H N N 340 
SER N    N N N 341 
SER CA   C N S 342 
SER C    C N N 343 
SER O    O N N 344 
SER CB   C N N 345 
SER OG   O N N 346 
SER OXT  O N N 347 
SER H    H N N 348 
SER H2   H N N 349 
SER HA   H N N 350 
SER HB2  H N N 351 
SER HB3  H N N 352 
SER HG   H N N 353 
SER HXT  H N N 354 
THR N    N N N 355 
THR CA   C N S 356 
THR C    C N N 357 
THR O    O N N 358 
THR CB   C N R 359 
THR OG1  O N N 360 
THR CG2  C N N 361 
THR OXT  O N N 362 
THR H    H N N 363 
THR H2   H N N 364 
THR HA   H N N 365 
THR HB   H N N 366 
THR HG1  H N N 367 
THR HG21 H N N 368 
THR HG22 H N N 369 
THR HG23 H N N 370 
THR HXT  H N N 371 
TRP N    N N N 372 
TRP CA   C N S 373 
TRP C    C N N 374 
TRP O    O N N 375 
TRP CB   C N N 376 
TRP CG   C Y N 377 
TRP CD1  C Y N 378 
TRP CD2  C Y N 379 
TRP NE1  N Y N 380 
TRP CE2  C Y N 381 
TRP CE3  C Y N 382 
TRP CZ2  C Y N 383 
TRP CZ3  C Y N 384 
TRP CH2  C Y N 385 
TRP OXT  O N N 386 
TRP H    H N N 387 
TRP H2   H N N 388 
TRP HA   H N N 389 
TRP HB2  H N N 390 
TRP HB3  H N N 391 
TRP HD1  H N N 392 
TRP HE1  H N N 393 
TRP HE3  H N N 394 
TRP HZ2  H N N 395 
TRP HZ3  H N N 396 
TRP HH2  H N N 397 
TRP HXT  H N N 398 
TYR N    N N N 399 
TYR CA   C N S 400 
TYR C    C N N 401 
TYR O    O N N 402 
TYR CB   C N N 403 
TYR CG   C Y N 404 
TYR CD1  C Y N 405 
TYR CD2  C Y N 406 
TYR CE1  C Y N 407 
TYR CE2  C Y N 408 
TYR CZ   C Y N 409 
TYR OH   O N N 410 
TYR OXT  O N N 411 
TYR H    H N N 412 
TYR H2   H N N 413 
TYR HA   H N N 414 
TYR HB2  H N N 415 
TYR HB3  H N N 416 
TYR HD1  H N N 417 
TYR HD2  H N N 418 
TYR HE1  H N N 419 
TYR HE2  H N N 420 
TYR HH   H N N 421 
TYR HXT  H N N 422 
VAL N    N N N 423 
VAL CA   C N S 424 
VAL C    C N N 425 
VAL O    O N N 426 
VAL CB   C N N 427 
VAL CG1  C N N 428 
VAL CG2  C N N 429 
VAL OXT  O N N 430 
VAL H    H N N 431 
VAL H2   H N N 432 
VAL HA   H N N 433 
VAL HB   H N N 434 
VAL HG11 H N N 435 
VAL HG12 H N N 436 
VAL HG13 H N N 437 
VAL HG21 H N N 438 
VAL HG22 H N N 439 
VAL HG23 H N N 440 
VAL HXT  H N N 441 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
ILE N   CA   sing N N 174 
ILE N   H    sing N N 175 
ILE N   H2   sing N N 176 
ILE CA  C    sing N N 177 
ILE CA  CB   sing N N 178 
ILE CA  HA   sing N N 179 
ILE C   O    doub N N 180 
ILE C   OXT  sing N N 181 
ILE CB  CG1  sing N N 182 
ILE CB  CG2  sing N N 183 
ILE CB  HB   sing N N 184 
ILE CG1 CD1  sing N N 185 
ILE CG1 HG12 sing N N 186 
ILE CG1 HG13 sing N N 187 
ILE CG2 HG21 sing N N 188 
ILE CG2 HG22 sing N N 189 
ILE CG2 HG23 sing N N 190 
ILE CD1 HD11 sing N N 191 
ILE CD1 HD12 sing N N 192 
ILE CD1 HD13 sing N N 193 
ILE OXT HXT  sing N N 194 
LEU N   CA   sing N N 195 
LEU N   H    sing N N 196 
LEU N   H2   sing N N 197 
LEU CA  C    sing N N 198 
LEU CA  CB   sing N N 199 
LEU CA  HA   sing N N 200 
LEU C   O    doub N N 201 
LEU C   OXT  sing N N 202 
LEU CB  CG   sing N N 203 
LEU CB  HB2  sing N N 204 
LEU CB  HB3  sing N N 205 
LEU CG  CD1  sing N N 206 
LEU CG  CD2  sing N N 207 
LEU CG  HG   sing N N 208 
LEU CD1 HD11 sing N N 209 
LEU CD1 HD12 sing N N 210 
LEU CD1 HD13 sing N N 211 
LEU CD2 HD21 sing N N 212 
LEU CD2 HD22 sing N N 213 
LEU CD2 HD23 sing N N 214 
LEU OXT HXT  sing N N 215 
LYS N   CA   sing N N 216 
LYS N   H    sing N N 217 
LYS N   H2   sing N N 218 
LYS CA  C    sing N N 219 
LYS CA  CB   sing N N 220 
LYS CA  HA   sing N N 221 
LYS C   O    doub N N 222 
LYS C   OXT  sing N N 223 
LYS CB  CG   sing N N 224 
LYS CB  HB2  sing N N 225 
LYS CB  HB3  sing N N 226 
LYS CG  CD   sing N N 227 
LYS CG  HG2  sing N N 228 
LYS CG  HG3  sing N N 229 
LYS CD  CE   sing N N 230 
LYS CD  HD2  sing N N 231 
LYS CD  HD3  sing N N 232 
LYS CE  NZ   sing N N 233 
LYS CE  HE2  sing N N 234 
LYS CE  HE3  sing N N 235 
LYS NZ  HZ1  sing N N 236 
LYS NZ  HZ2  sing N N 237 
LYS NZ  HZ3  sing N N 238 
LYS OXT HXT  sing N N 239 
MET N   CA   sing N N 240 
MET N   H    sing N N 241 
MET N   H2   sing N N 242 
MET CA  C    sing N N 243 
MET CA  CB   sing N N 244 
MET CA  HA   sing N N 245 
MET C   O    doub N N 246 
MET C   OXT  sing N N 247 
MET CB  CG   sing N N 248 
MET CB  HB2  sing N N 249 
MET CB  HB3  sing N N 250 
MET CG  SD   sing N N 251 
MET CG  HG2  sing N N 252 
MET CG  HG3  sing N N 253 
MET SD  CE   sing N N 254 
MET CE  HE1  sing N N 255 
MET CE  HE2  sing N N 256 
MET CE  HE3  sing N N 257 
MET OXT HXT  sing N N 258 
NAG C1  C2   sing N N 259 
NAG C1  O1   sing N N 260 
NAG C1  O5   sing N N 261 
NAG C1  H1   sing N N 262 
NAG C2  C3   sing N N 263 
NAG C2  N2   sing N N 264 
NAG C2  H2   sing N N 265 
NAG C3  C4   sing N N 266 
NAG C3  O3   sing N N 267 
NAG C3  H3   sing N N 268 
NAG C4  C5   sing N N 269 
NAG C4  O4   sing N N 270 
NAG C4  H4   sing N N 271 
NAG C5  C6   sing N N 272 
NAG C5  O5   sing N N 273 
NAG C5  H5   sing N N 274 
NAG C6  O6   sing N N 275 
NAG C6  H61  sing N N 276 
NAG C6  H62  sing N N 277 
NAG C7  C8   sing N N 278 
NAG C7  N2   sing N N 279 
NAG C7  O7   doub N N 280 
NAG C8  H81  sing N N 281 
NAG C8  H82  sing N N 282 
NAG C8  H83  sing N N 283 
NAG N2  HN2  sing N N 284 
NAG O1  HO1  sing N N 285 
NAG O3  HO3  sing N N 286 
NAG O4  HO4  sing N N 287 
NAG O6  HO6  sing N N 288 
PHE N   CA   sing N N 289 
PHE N   H    sing N N 290 
PHE N   H2   sing N N 291 
PHE CA  C    sing N N 292 
PHE CA  CB   sing N N 293 
PHE CA  HA   sing N N 294 
PHE C   O    doub N N 295 
PHE C   OXT  sing N N 296 
PHE CB  CG   sing N N 297 
PHE CB  HB2  sing N N 298 
PHE CB  HB3  sing N N 299 
PHE CG  CD1  doub Y N 300 
PHE CG  CD2  sing Y N 301 
PHE CD1 CE1  sing Y N 302 
PHE CD1 HD1  sing N N 303 
PHE CD2 CE2  doub Y N 304 
PHE CD2 HD2  sing N N 305 
PHE CE1 CZ   doub Y N 306 
PHE CE1 HE1  sing N N 307 
PHE CE2 CZ   sing Y N 308 
PHE CE2 HE2  sing N N 309 
PHE CZ  HZ   sing N N 310 
PHE OXT HXT  sing N N 311 
PRO N   CA   sing N N 312 
PRO N   CD   sing N N 313 
PRO N   H    sing N N 314 
PRO CA  C    sing N N 315 
PRO CA  CB   sing N N 316 
PRO CA  HA   sing N N 317 
PRO C   O    doub N N 318 
PRO C   OXT  sing N N 319 
PRO CB  CG   sing N N 320 
PRO CB  HB2  sing N N 321 
PRO CB  HB3  sing N N 322 
PRO CG  CD   sing N N 323 
PRO CG  HG2  sing N N 324 
PRO CG  HG3  sing N N 325 
PRO CD  HD2  sing N N 326 
PRO CD  HD3  sing N N 327 
PRO OXT HXT  sing N N 328 
SER N   CA   sing N N 329 
SER N   H    sing N N 330 
SER N   H2   sing N N 331 
SER CA  C    sing N N 332 
SER CA  CB   sing N N 333 
SER CA  HA   sing N N 334 
SER C   O    doub N N 335 
SER C   OXT  sing N N 336 
SER CB  OG   sing N N 337 
SER CB  HB2  sing N N 338 
SER CB  HB3  sing N N 339 
SER OG  HG   sing N N 340 
SER OXT HXT  sing N N 341 
THR N   CA   sing N N 342 
THR N   H    sing N N 343 
THR N   H2   sing N N 344 
THR CA  C    sing N N 345 
THR CA  CB   sing N N 346 
THR CA  HA   sing N N 347 
THR C   O    doub N N 348 
THR C   OXT  sing N N 349 
THR CB  OG1  sing N N 350 
THR CB  CG2  sing N N 351 
THR CB  HB   sing N N 352 
THR OG1 HG1  sing N N 353 
THR CG2 HG21 sing N N 354 
THR CG2 HG22 sing N N 355 
THR CG2 HG23 sing N N 356 
THR OXT HXT  sing N N 357 
TRP N   CA   sing N N 358 
TRP N   H    sing N N 359 
TRP N   H2   sing N N 360 
TRP CA  C    sing N N 361 
TRP CA  CB   sing N N 362 
TRP CA  HA   sing N N 363 
TRP C   O    doub N N 364 
TRP C   OXT  sing N N 365 
TRP CB  CG   sing N N 366 
TRP CB  HB2  sing N N 367 
TRP CB  HB3  sing N N 368 
TRP CG  CD1  doub Y N 369 
TRP CG  CD2  sing Y N 370 
TRP CD1 NE1  sing Y N 371 
TRP CD1 HD1  sing N N 372 
TRP CD2 CE2  doub Y N 373 
TRP CD2 CE3  sing Y N 374 
TRP NE1 CE2  sing Y N 375 
TRP NE1 HE1  sing N N 376 
TRP CE2 CZ2  sing Y N 377 
TRP CE3 CZ3  doub Y N 378 
TRP CE3 HE3  sing N N 379 
TRP CZ2 CH2  doub Y N 380 
TRP CZ2 HZ2  sing N N 381 
TRP CZ3 CH2  sing Y N 382 
TRP CZ3 HZ3  sing N N 383 
TRP CH2 HH2  sing N N 384 
TRP OXT HXT  sing N N 385 
TYR N   CA   sing N N 386 
TYR N   H    sing N N 387 
TYR N   H2   sing N N 388 
TYR CA  C    sing N N 389 
TYR CA  CB   sing N N 390 
TYR CA  HA   sing N N 391 
TYR C   O    doub N N 392 
TYR C   OXT  sing N N 393 
TYR CB  CG   sing N N 394 
TYR CB  HB2  sing N N 395 
TYR CB  HB3  sing N N 396 
TYR CG  CD1  doub Y N 397 
TYR CG  CD2  sing Y N 398 
TYR CD1 CE1  sing Y N 399 
TYR CD1 HD1  sing N N 400 
TYR CD2 CE2  doub Y N 401 
TYR CD2 HD2  sing N N 402 
TYR CE1 CZ   doub Y N 403 
TYR CE1 HE1  sing N N 404 
TYR CE2 CZ   sing Y N 405 
TYR CE2 HE2  sing N N 406 
TYR CZ  OH   sing N N 407 
TYR OH  HH   sing N N 408 
TYR OXT HXT  sing N N 409 
VAL N   CA   sing N N 410 
VAL N   H    sing N N 411 
VAL N   H2   sing N N 412 
VAL CA  C    sing N N 413 
VAL CA  CB   sing N N 414 
VAL CA  HA   sing N N 415 
VAL C   O    doub N N 416 
VAL C   OXT  sing N N 417 
VAL CB  CG1  sing N N 418 
VAL CB  CG2  sing N N 419 
VAL CB  HB   sing N N 420 
VAL CG1 HG11 sing N N 421 
VAL CG1 HG12 sing N N 422 
VAL CG1 HG13 sing N N 423 
VAL CG2 HG21 sing N N 424 
VAL CG2 HG22 sing N N 425 
VAL CG2 HG23 sing N N 426 
VAL OXT HXT  sing N N 427 
# 
_pdbx_audit_support.funding_organization   'Bill & Melinda Gates Foundation' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           INV-004923 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
6 NAG 1 n 
6 NAG 2 n 
6 BMA 3 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8GF2 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9CPV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009047 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009047 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004446 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLU A 1 1   ? 6.826   23.403  -28.647 1.00 75.97  ? 1   GLU H N   1 
ATOM   2    C CA  . GLU A 1 1   ? 8.237   23.509  -28.295 1.00 75.43  ? 1   GLU H CA  1 
ATOM   3    C C   . GLU A 1 1   ? 9.008   22.265  -28.722 1.00 73.10  ? 1   GLU H C   1 
ATOM   4    O O   . GLU A 1 1   ? 10.171  22.090  -28.357 1.00 79.71  ? 1   GLU H O   1 
ATOM   5    C CB  . GLU A 1 1   ? 8.402   23.727  -26.790 1.00 79.10  ? 1   GLU H CB  1 
ATOM   6    C CG  . GLU A 1 1   ? 7.936   22.553  -25.946 1.00 81.63  ? 1   GLU H CG  1 
ATOM   7    C CD  . GLU A 1 1   ? 8.408   22.641  -24.508 1.00 84.64  ? 1   GLU H CD  1 
ATOM   8    O OE1 . GLU A 1 1   ? 9.110   23.617  -24.169 1.00 81.24  ? 1   GLU H OE1 1 
ATOM   9    O OE2 . GLU A 1 1   ? 8.078   21.732  -23.717 1.00 77.75  ? 1   GLU H OE2 1 
ATOM   10   N N   . VAL A 1 2   ? 8.353   21.398  -29.494 1.00 62.98  ? 2   VAL H N   1 
ATOM   11   C CA  . VAL A 1 2   ? 8.984   20.159  -29.930 1.00 52.42  ? 2   VAL H CA  1 
ATOM   12   C C   . VAL A 1 2   ? 10.091  20.473  -30.927 1.00 49.44  ? 2   VAL H C   1 
ATOM   13   O O   . VAL A 1 2   ? 9.890   21.227  -31.889 1.00 37.75  ? 2   VAL H O   1 
ATOM   14   C CB  . VAL A 1 2   ? 7.943   19.207  -30.536 1.00 55.22  ? 2   VAL H CB  1 
ATOM   15   C CG1 . VAL A 1 2   ? 8.622   17.972  -31.109 1.00 53.60  ? 2   VAL H CG1 1 
ATOM   16   C CG2 . VAL A 1 2   ? 6.919   18.811  -29.489 1.00 60.10  ? 2   VAL H CG2 1 
ATOM   17   N N   . GLN A 1 3   ? 11.271  19.904  -30.692 1.00 47.61  ? 3   GLN H N   1 
ATOM   18   C CA  . GLN A 1 3   ? 12.393  20.019  -31.610 1.00 48.72  ? 3   GLN H CA  1 
ATOM   19   C C   . GLN A 1 3   ? 13.099  18.674  -31.699 1.00 48.83  ? 3   GLN H C   1 
ATOM   20   O O   . GLN A 1 3   ? 13.052  17.869  -30.766 1.00 45.57  ? 3   GLN H O   1 
ATOM   21   C CB  . GLN A 1 3   ? 13.381  21.108  -31.174 1.00 47.38  ? 3   GLN H CB  1 
ATOM   22   C CG  . GLN A 1 3   ? 14.016  20.866  -29.817 1.00 67.84  ? 3   GLN H CG  1 
ATOM   23   C CD  . GLN A 1 3   ? 15.153  21.826  -29.531 1.00 70.83  ? 3   GLN H CD  1 
ATOM   24   O OE1 . GLN A 1 3   ? 15.297  22.851  -30.198 1.00 63.61  ? 3   GLN H OE1 1 
ATOM   25   N NE2 . GLN A 1 3   ? 15.974  21.493  -28.541 1.00 67.01  ? 3   GLN H NE2 1 
ATOM   26   N N   . LEU A 1 4   ? 13.753  18.439  -32.834 1.00 47.38  ? 4   LEU H N   1 
ATOM   27   C CA  . LEU A 1 4   ? 14.447  17.188  -33.104 1.00 40.30  ? 4   LEU H CA  1 
ATOM   28   C C   . LEU A 1 4   ? 15.925  17.467  -33.335 1.00 48.12  ? 4   LEU H C   1 
ATOM   29   O O   . LEU A 1 4   ? 16.277  18.386  -34.083 1.00 55.72  ? 4   LEU H O   1 
ATOM   30   C CB  . LEU A 1 4   ? 13.841  16.479  -34.319 1.00 53.68  ? 4   LEU H CB  1 
ATOM   31   C CG  . LEU A 1 4   ? 12.378  16.046  -34.191 1.00 55.62  ? 4   LEU H CG  1 
ATOM   32   C CD1 . LEU A 1 4   ? 11.803  15.695  -35.552 1.00 42.69  ? 4   LEU H CD1 1 
ATOM   33   C CD2 . LEU A 1 4   ? 12.244  14.870  -33.234 1.00 33.20  ? 4   LEU H CD2 1 
ATOM   34   N N   . VAL A 1 5   ? 16.782  16.681  -32.688 1.00 48.78  ? 5   VAL H N   1 
ATOM   35   C CA  . VAL A 1 5   ? 18.230  16.776  -32.842 1.00 45.84  ? 5   VAL H CA  1 
ATOM   36   C C   . VAL A 1 5   ? 18.752  15.405  -33.248 1.00 40.88  ? 5   VAL H C   1 
ATOM   37   O O   . VAL A 1 5   ? 18.411  14.397  -32.619 1.00 39.34  ? 5   VAL H O   1 
ATOM   38   C CB  . VAL A 1 5   ? 18.913  17.261  -31.550 1.00 46.32  ? 5   VAL H CB  1 
ATOM   39   C CG1 . VAL A 1 5   ? 20.362  17.636  -31.823 1.00 56.20  ? 5   VAL H CG1 1 
ATOM   40   C CG2 . VAL A 1 5   ? 18.155  18.437  -30.950 1.00 35.12  ? 5   VAL H CG2 1 
ATOM   41   N N   . GLN A 1 6   ? 19.579  15.369  -34.288 1.00 41.06  ? 6   GLN H N   1 
ATOM   42   C CA  . GLN A 1 6   ? 20.066  14.122  -34.860 1.00 44.08  ? 6   GLN H CA  1 
ATOM   43   C C   . GLN A 1 6   ? 21.530  13.898  -34.502 1.00 44.50  ? 6   GLN H C   1 
ATOM   44   O O   . GLN A 1 6   ? 22.221  14.786  -33.995 1.00 39.61  ? 6   GLN H O   1 
ATOM   45   C CB  . GLN A 1 6   ? 19.892  14.116  -36.383 1.00 49.40  ? 6   GLN H CB  1 
ATOM   46   C CG  . GLN A 1 6   ? 18.520  14.554  -36.847 1.00 46.24  ? 6   GLN H CG  1 
ATOM   47   C CD  . GLN A 1 6   ? 18.241  14.162  -38.282 1.00 43.84  ? 6   GLN H CD  1 
ATOM   48   O OE1 . GLN A 1 6   ? 17.695  14.947  -39.057 1.00 43.14  ? 6   GLN H OE1 1 
ATOM   49   N NE2 . GLN A 1 6   ? 18.607  12.935  -38.641 1.00 37.24  ? 6   GLN H NE2 1 
ATOM   50   N N   . SER A 1 7   ? 21.995  12.682  -34.781 1.00 42.17  ? 7   SER H N   1 
ATOM   51   C CA  . SER A 1 7   ? 23.376  12.308  -34.521 1.00 40.40  ? 7   SER H CA  1 
ATOM   52   C C   . SER A 1 7   ? 24.311  12.959  -35.541 1.00 44.91  ? 7   SER H C   1 
ATOM   53   O O   . SER A 1 7   ? 23.889  13.495  -36.570 1.00 45.41  ? 7   SER H O   1 
ATOM   54   C CB  . SER A 1 7   ? 23.529  10.788  -34.545 1.00 37.38  ? 7   SER H CB  1 
ATOM   55   O OG  . SER A 1 7   ? 23.062  10.247  -35.768 1.00 43.81  ? 7   SER H OG  1 
ATOM   56   N N   . GLY A 1 8   ? 25.605  12.897  -35.244 1.00 36.05  ? 8   GLY H N   1 
ATOM   57   C CA  . GLY A 1 8   ? 26.602  13.579  -36.040 1.00 50.79  ? 8   GLY H CA  1 
ATOM   58   C C   . GLY A 1 8   ? 26.870  12.899  -37.371 1.00 46.82  ? 8   GLY H C   1 
ATOM   59   O O   . GLY A 1 8   ? 26.344  11.833  -37.695 1.00 46.49  ? 8   GLY H O   1 
ATOM   60   N N   . THR A 1 9   ? 27.717  13.555  -38.163 1.00 42.22  ? 9   THR H N   1 
ATOM   61   C CA  . THR A 1 9   ? 28.068  13.054  -39.485 1.00 44.46  ? 9   THR H CA  1 
ATOM   62   C C   . THR A 1 9   ? 28.781  11.711  -39.375 1.00 45.85  ? 9   THR H C   1 
ATOM   63   O O   . THR A 1 9   ? 29.589  11.490  -38.470 1.00 59.17  ? 9   THR H O   1 
ATOM   64   C CB  . THR A 1 9   ? 28.955  14.067  -40.212 1.00 37.66  ? 9   THR H CB  1 
ATOM   65   O OG1 . THR A 1 9   ? 28.360  15.369  -40.130 1.00 29.62  ? 9   THR H OG1 1 
ATOM   66   C CG2 . THR A 1 9   ? 29.122  13.689  -41.677 1.00 40.66  ? 9   THR H CG2 1 
ATOM   67   N N   . GLU A 1 10  ? 28.470  10.808  -40.303 1.00 43.06  ? 10  GLU H N   1 
ATOM   68   C CA  . GLU A 1 10  ? 29.026  9.462   -40.315 1.00 39.20  ? 10  GLU H CA  1 
ATOM   69   C C   . GLU A 1 10  ? 29.718  9.201   -41.644 1.00 48.90  ? 10  GLU H C   1 
ATOM   70   O O   . GLU A 1 10  ? 29.140  9.444   -42.709 1.00 50.62  ? 10  GLU H O   1 
ATOM   71   C CB  . GLU A 1 10  ? 27.935  8.414   -40.078 1.00 38.90  ? 10  GLU H CB  1 
ATOM   72   C CG  . GLU A 1 10  ? 27.352  8.416   -38.673 1.00 51.80  ? 10  GLU H CG  1 
ATOM   73   C CD  . GLU A 1 10  ? 28.171  7.591   -37.694 1.00 56.30  ? 10  GLU H CD  1 
ATOM   74   O OE1 . GLU A 1 10  ? 29.380  7.394   -37.937 1.00 62.73  ? 10  GLU H OE1 1 
ATOM   75   O OE2 . GLU A 1 10  ? 27.601  7.129   -36.682 1.00 42.80  ? 10  GLU H OE2 1 
ATOM   76   N N   . VAL A 1 11  ? 30.950  8.704   -41.577 1.00 53.37  ? 11  VAL H N   1 
ATOM   77   C CA  . VAL A 1 11  ? 31.696  8.252   -42.746 1.00 45.92  ? 11  VAL H CA  1 
ATOM   78   C C   . VAL A 1 11  ? 31.985  6.771   -42.549 1.00 40.83  ? 11  VAL H C   1 
ATOM   79   O O   . VAL A 1 11  ? 32.623  6.385   -41.562 1.00 47.30  ? 11  VAL H O   1 
ATOM   80   C CB  . VAL A 1 11  ? 32.997  9.046   -42.942 1.00 43.17  ? 11  VAL H CB  1 
ATOM   81   C CG1 . VAL A 1 11  ? 33.679  8.635   -44.239 1.00 41.45  ? 11  VAL H CG1 1 
ATOM   82   C CG2 . VAL A 1 11  ? 32.717  10.542  -42.930 1.00 41.42  ? 11  VAL H CG2 1 
ATOM   83   N N   . LYS A 1 12  ? 31.517  5.945   -43.482 1.00 37.05  ? 12  LYS H N   1 
ATOM   84   C CA  . LYS A 1 12  ? 31.608  4.500   -43.342 1.00 47.82  ? 12  LYS H CA  1 
ATOM   85   C C   . LYS A 1 12  ? 32.047  3.882   -44.661 1.00 44.67  ? 12  LYS H C   1 
ATOM   86   O O   . LYS A 1 12  ? 31.914  4.482   -45.730 1.00 42.35  ? 12  LYS H O   1 
ATOM   87   C CB  . LYS A 1 12  ? 30.270  3.890   -42.903 1.00 52.63  ? 12  LYS H CB  1 
ATOM   88   C CG  . LYS A 1 12  ? 29.774  4.357   -41.543 1.00 52.72  ? 12  LYS H CG  1 
ATOM   89   C CD  . LYS A 1 12  ? 30.658  3.842   -40.421 1.00 50.97  ? 12  LYS H CD  1 
ATOM   90   C CE  . LYS A 1 12  ? 30.114  4.249   -39.063 1.00 50.64  ? 12  LYS H CE  1 
ATOM   91   N NZ  . LYS A 1 12  ? 30.927  3.695   -37.947 1.00 55.80  ? 12  LYS H NZ  1 
ATOM   92   N N   . LYS A 1 13  ? 32.586  2.657   -44.567 1.00 47.66  ? 13  LYS H N   1 
ATOM   93   C CA  . LYS A 1 13  ? 32.950  1.876   -45.736 1.00 51.20  ? 13  LYS H CA  1 
ATOM   94   C C   . LYS A 1 13  ? 31.839  0.888   -46.079 1.00 47.26  ? 13  LYS H C   1 
ATOM   95   O O   . LYS A 1 13  ? 31.073  0.479   -45.200 1.00 52.12  ? 13  LYS H O   1 
ATOM   96   C CB  . LYS A 1 13  ? 34.260  1.119   -45.496 1.00 41.55  ? 13  LYS H CB  1 
ATOM   97   C CG  . LYS A 1 13  ? 35.451  2.030   -45.242 1.00 50.54  ? 13  LYS H CG  1 
ATOM   98   C CD  . LYS A 1 13  ? 36.735  1.445   -45.807 1.00 58.56  ? 13  LYS H CD  1 
ATOM   99   C CE  . LYS A 1 13  ? 37.880  2.441   -45.706 1.00 47.65  ? 13  LYS H CE  1 
ATOM   100  N NZ  . LYS A 1 13  ? 39.108  1.956   -46.394 1.00 60.49  ? 13  LYS H NZ  1 
ATOM   101  N N   . PRO A 1 14  ? 31.714  0.501   -47.350 1.00 43.87  ? 14  PRO H N   1 
ATOM   102  C CA  . PRO A 1 14  ? 30.619  -0.397  -47.741 1.00 45.43  ? 14  PRO H CA  1 
ATOM   103  C C   . PRO A 1 14  ? 30.676  -1.720  -46.991 1.00 46.22  ? 14  PRO H C   1 
ATOM   104  O O   . PRO A 1 14  ? 31.750  -2.271  -46.739 1.00 42.88  ? 14  PRO H O   1 
ATOM   105  C CB  . PRO A 1 14  ? 30.842  -0.593  -49.246 1.00 34.07  ? 14  PRO H CB  1 
ATOM   106  C CG  . PRO A 1 14  ? 31.608  0.614   -49.671 1.00 49.37  ? 14  PRO H CG  1 
ATOM   107  C CD  . PRO A 1 14  ? 32.499  0.948   -48.513 1.00 50.01  ? 14  PRO H CD  1 
ATOM   108  N N   . GLY A 1 15  ? 29.496  -2.226  -46.635 1.00 35.47  ? 15  GLY H N   1 
ATOM   109  C CA  . GLY A 1 15  ? 29.371  -3.445  -45.873 1.00 32.31  ? 15  GLY H CA  1 
ATOM   110  C C   . GLY A 1 15  ? 29.297  -3.256  -44.373 1.00 40.44  ? 15  GLY H C   1 
ATOM   111  O O   . GLY A 1 15  ? 28.904  -4.190  -43.665 1.00 50.88  ? 15  GLY H O   1 
ATOM   112  N N   . GLU A 1 16  ? 29.657  -2.079  -43.868 1.00 43.10  ? 16  GLU H N   1 
ATOM   113  C CA  . GLU A 1 16  ? 29.604  -1.822  -42.439 1.00 45.51  ? 16  GLU H CA  1 
ATOM   114  C C   . GLU A 1 16  ? 28.172  -1.524  -41.998 1.00 50.99  ? 16  GLU H C   1 
ATOM   115  O O   . GLU A 1 16  ? 27.279  -1.262  -42.809 1.00 49.56  ? 16  GLU H O   1 
ATOM   116  C CB  . GLU A 1 16  ? 30.529  -0.666  -42.061 1.00 44.72  ? 16  GLU H CB  1 
ATOM   117  C CG  . GLU A 1 16  ? 32.009  -0.981  -42.200 1.00 54.78  ? 16  GLU H CG  1 
ATOM   118  C CD  . GLU A 1 16  ? 32.889  0.027   -41.486 1.00 59.53  ? 16  GLU H CD  1 
ATOM   119  O OE1 . GLU A 1 16  ? 34.124  -0.159  -41.480 1.00 69.53  ? 16  GLU H OE1 1 
ATOM   120  O OE2 . GLU A 1 16  ? 32.346  1.003   -40.928 1.00 61.48  ? 16  GLU H OE2 1 
ATOM   121  N N   . SER A 1 17  ? 27.960  -1.570  -40.687 1.00 55.62  ? 17  SER H N   1 
ATOM   122  C CA  . SER A 1 17  ? 26.661  -1.299  -40.089 1.00 57.16  ? 17  SER H CA  1 
ATOM   123  C C   . SER A 1 17  ? 26.642  0.104   -39.497 1.00 64.40  ? 17  SER H C   1 
ATOM   124  O O   . SER A 1 17  ? 27.621  0.548   -38.889 1.00 66.72  ? 17  SER H O   1 
ATOM   125  C CB  . SER A 1 17  ? 26.332  -2.332  -39.009 1.00 42.62  ? 17  SER H CB  1 
ATOM   126  O OG  . SER A 1 17  ? 27.336  -2.368  -38.009 1.00 62.72  ? 17  SER H OG  1 
ATOM   127  N N   . LEU A 1 18  ? 25.523  0.803   -39.686 1.00 56.13  ? 18  LEU H N   1 
ATOM   128  C CA  . LEU A 1 18  ? 25.350  2.160   -39.189 1.00 56.94  ? 18  LEU H CA  1 
ATOM   129  C C   . LEU A 1 18  ? 23.998  2.280   -38.500 1.00 54.03  ? 18  LEU H C   1 
ATOM   130  O O   . LEU A 1 18  ? 23.022  1.636   -38.893 1.00 45.23  ? 18  LEU H O   1 
ATOM   131  C CB  . LEU A 1 18  ? 25.469  3.193   -40.327 1.00 44.31  ? 18  LEU H CB  1 
ATOM   132  C CG  . LEU A 1 18  ? 25.251  4.690   -40.074 1.00 43.91  ? 18  LEU H CG  1 
ATOM   133  C CD1 . LEU A 1 18  ? 25.951  5.176   -38.816 1.00 65.24  ? 18  LEU H CD1 1 
ATOM   134  C CD2 . LEU A 1 18  ? 25.740  5.477   -41.275 1.00 47.00  ? 18  LEU H CD2 1 
ATOM   135  N N   . LYS A 1 19  ? 23.956  3.119   -37.463 1.00 56.74  ? 19  LYS H N   1 
ATOM   136  C CA  . LYS A 1 19  ? 22.749  3.310   -36.662 1.00 40.55  ? 19  LYS H CA  1 
ATOM   137  C C   . LYS A 1 19  ? 22.725  4.771   -36.218 1.00 45.65  ? 19  LYS H C   1 
ATOM   138  O O   . LYS A 1 19  ? 23.348  5.121   -35.212 1.00 54.94  ? 19  LYS H O   1 
ATOM   139  C CB  . LYS A 1 19  ? 22.748  2.359   -35.475 1.00 37.16  ? 19  LYS H CB  1 
ATOM   140  C CG  . LYS A 1 19  ? 21.422  2.195   -34.773 1.00 49.39  ? 19  LYS H CG  1 
ATOM   141  C CD  . LYS A 1 19  ? 21.486  1.025   -33.809 1.00 70.31  ? 19  LYS H CD  1 
ATOM   142  C CE  . LYS A 1 19  ? 20.609  -0.105  -34.324 1.00 67.26  ? 19  LYS H CE  1 
ATOM   143  N NZ  . LYS A 1 19  ? 20.844  -1.425  -33.671 1.00 46.84  ? 19  LYS H NZ  1 
ATOM   144  N N   . ILE A 1 20  ? 22.010  5.615   -36.974 1.00 48.60  ? 20  ILE H N   1 
ATOM   145  C CA  . ILE A 1 20  ? 21.865  7.030   -36.648 1.00 49.10  ? 20  ILE H CA  1 
ATOM   146  C C   . ILE A 1 20  ? 20.616  7.216   -35.798 1.00 49.01  ? 20  ILE H C   1 
ATOM   147  O O   . ILE A 1 20  ? 19.659  6.438   -35.882 1.00 49.90  ? 20  ILE H O   1 
ATOM   148  C CB  . ILE A 1 20  ? 21.818  7.900   -37.923 1.00 40.26  ? 20  ILE H CB  1 
ATOM   149  C CG1 . ILE A 1 20  ? 20.776  7.364   -38.907 1.00 42.95  ? 20  ILE H CG1 1 
ATOM   150  C CG2 . ILE A 1 20  ? 23.194  7.975   -38.571 1.00 45.89  ? 20  ILE H CG2 1 
ATOM   151  C CD1 . ILE A 1 20  ? 20.633  8.202   -40.162 1.00 38.15  ? 20  ILE H CD1 1 
ATOM   152  N N   . SER A 1 21  ? 20.617  8.261   -34.971 1.00 51.02  ? 21  SER H N   1 
ATOM   153  C CA  . SER A 1 21  ? 19.570  8.478   -33.984 1.00 46.08  ? 21  SER H CA  1 
ATOM   154  C C   . SER A 1 21  ? 18.941  9.856   -34.149 1.00 47.36  ? 21  SER H C   1 
ATOM   155  O O   . SER A 1 21  ? 19.512  10.758  -34.767 1.00 51.86  ? 21  SER H O   1 
ATOM   156  C CB  . SER A 1 21  ? 20.113  8.326   -32.555 1.00 35.04  ? 21  SER H CB  1 
ATOM   157  O OG  . SER A 1 21  ? 21.095  9.308   -32.272 1.00 64.40  ? 21  SER H OG  1 
ATOM   158  N N   . CYS A 1 22  ? 17.746  10.003  -33.575 1.00 52.94  ? 22  CYS H N   1 
ATOM   159  C CA  . CYS A 1 22  ? 16.967  11.241  -33.651 1.00 48.24  ? 22  CYS H CA  1 
ATOM   160  C C   . CYS A 1 22  ? 16.287  11.433  -32.298 1.00 46.10  ? 22  CYS H C   1 
ATOM   161  O O   . CYS A 1 22  ? 15.287  10.772  -32.002 1.00 56.42  ? 22  CYS H O   1 
ATOM   162  C CB  . CYS A 1 22  ? 15.952  11.177  -34.787 1.00 47.69  ? 22  CYS H CB  1 
ATOM   163  S SG  . CYS A 1 22  ? 14.797  12.568  -34.919 1.00 44.06  ? 22  CYS H SG  1 
ATOM   164  N N   . LYS A 1 23  ? 16.832  12.331  -31.481 1.00 57.48  ? 23  LYS H N   1 
ATOM   165  C CA  . LYS A 1 23  ? 16.317  12.601  -30.144 1.00 52.97  ? 23  LYS H CA  1 
ATOM   166  C C   . LYS A 1 23  ? 15.426  13.837  -30.173 1.00 54.17  ? 23  LYS H C   1 
ATOM   167  O O   . LYS A 1 23  ? 15.819  14.881  -30.706 1.00 56.71  ? 23  LYS H O   1 
ATOM   168  C CB  . LYS A 1 23  ? 17.462  12.801  -29.149 1.00 43.93  ? 23  LYS H CB  1 
ATOM   169  C CG  . LYS A 1 23  ? 17.031  13.335  -27.789 1.00 36.68  ? 23  LYS H CG  1 
ATOM   170  C CD  . LYS A 1 23  ? 17.047  12.250  -26.723 1.00 53.10  ? 23  LYS H CD  1 
ATOM   171  C CE  . LYS A 1 23  ? 16.684  12.814  -25.356 1.00 54.34  ? 23  LYS H CE  1 
ATOM   172  N NZ  . LYS A 1 23  ? 15.273  13.293  -25.308 1.00 66.50  ? 23  LYS H NZ  1 
ATOM   173  N N   . GLY A 1 24  ? 14.232  13.716  -29.598 1.00 39.93  ? 24  GLY H N   1 
ATOM   174  C CA  . GLY A 1 24  ? 13.304  14.828  -29.534 1.00 47.99  ? 24  GLY H CA  1 
ATOM   175  C C   . GLY A 1 24  ? 13.076  15.324  -28.121 1.00 57.61  ? 24  GLY H C   1 
ATOM   176  O O   . GLY A 1 24  ? 13.286  14.581  -27.157 1.00 55.40  ? 24  GLY H O   1 
ATOM   177  N N   . SER A 1 25  ? 12.648  16.578  -27.982 1.00 55.96  ? 25  SER H N   1 
ATOM   178  C CA  . SER A 1 25  ? 12.426  17.174  -26.674 1.00 48.79  ? 25  SER H CA  1 
ATOM   179  C C   . SER A 1 25  ? 11.233  18.118  -26.740 1.00 59.82  ? 25  SER H C   1 
ATOM   180  O O   . SER A 1 25  ? 10.866  18.619  -27.805 1.00 59.97  ? 25  SER H O   1 
ATOM   181  C CB  . SER A 1 25  ? 13.665  17.931  -26.178 1.00 44.17  ? 25  SER H CB  1 
ATOM   182  O OG  . SER A 1 25  ? 13.939  19.053  -27.000 1.00 63.79  ? 25  SER H OG  1 
ATOM   183  N N   . GLY A 1 26  ? 10.632  18.351  -25.582 1.00 64.93  ? 26  GLY H N   1 
ATOM   184  C CA  . GLY A 1 26  ? 9.545   19.298  -25.443 1.00 61.61  ? 26  GLY H CA  1 
ATOM   185  C C   . GLY A 1 26  ? 8.250   18.632  -25.014 1.00 65.18  ? 26  GLY H C   1 
ATOM   186  O O   . GLY A 1 26  ? 8.090   17.413  -25.055 1.00 56.72  ? 26  GLY H O   1 
ATOM   187  N N   . LYS A 1 27  ? 7.319   19.482  -24.591 1.00 61.68  ? 27  LYS H N   1 
ATOM   188  C CA  . LYS A 1 27  ? 5.975   19.032  -24.265 1.00 66.44  ? 27  LYS H CA  1 
ATOM   189  C C   . LYS A 1 27  ? 5.216   18.663  -25.537 1.00 68.61  ? 27  LYS H C   1 
ATOM   190  O O   . LYS A 1 27  ? 5.552   19.099  -26.641 1.00 66.18  ? 27  LYS H O   1 
ATOM   191  C CB  . LYS A 1 27  ? 5.223   20.113  -23.489 1.00 71.91  ? 27  LYS H CB  1 
ATOM   192  C CG  . LYS A 1 27  ? 5.456   20.061  -21.990 1.00 72.86  ? 27  LYS H CG  1 
ATOM   193  C CD  . LYS A 1 27  ? 4.394   19.217  -21.307 1.00 89.01  ? 27  LYS H CD  1 
ATOM   194  C CE  . LYS A 1 27  ? 4.929   18.565  -20.047 1.00 79.81  ? 27  LYS H CE  1 
ATOM   195  N NZ  . LYS A 1 27  ? 5.838   17.431  -20.373 1.00 75.19  ? 27  LYS H NZ  1 
ATOM   196  N N   . SER A 1 28  ? 4.186   17.834  -25.363 1.00 62.35  ? 28  SER H N   1 
ATOM   197  C CA  . SER A 1 28  ? 3.374   17.282  -26.444 1.00 59.31  ? 28  SER H CA  1 
ATOM   198  C C   . SER A 1 28  ? 4.173   16.381  -27.376 1.00 59.48  ? 28  SER H C   1 
ATOM   199  O O   . SER A 1 28  ? 3.803   16.216  -28.543 1.00 59.89  ? 28  SER H O   1 
ATOM   200  C CB  . SER A 1 28  ? 2.680   18.385  -27.255 1.00 51.58  ? 28  SER H CB  1 
ATOM   201  O OG  . SER A 1 28  ? 2.041   19.318  -26.399 1.00 70.16  ? 28  SER H OG  1 
ATOM   202  N N   . LEU A 1 29  ? 5.261   15.790  -26.882 1.00 54.51  ? 29  LEU H N   1 
ATOM   203  C CA  . LEU A 1 29  ? 6.069   14.889  -27.694 1.00 50.61  ? 29  LEU H CA  1 
ATOM   204  C C   . LEU A 1 29  ? 5.414   13.526  -27.872 1.00 46.01  ? 29  LEU H C   1 
ATOM   205  O O   . LEU A 1 29  ? 5.651   12.859  -28.885 1.00 47.18  ? 29  LEU H O   1 
ATOM   206  C CB  . LEU A 1 29  ? 7.446   14.721  -27.052 1.00 49.21  ? 29  LEU H CB  1 
ATOM   207  C CG  . LEU A 1 29  ? 8.364   13.632  -27.592 1.00 46.88  ? 29  LEU H CG  1 
ATOM   208  C CD1 . LEU A 1 29  ? 8.984   14.043  -28.917 1.00 53.86  ? 29  LEU H CD1 1 
ATOM   209  C CD2 . LEU A 1 29  ? 9.427   13.356  -26.562 1.00 50.35  ? 29  LEU H CD2 1 
ATOM   210  N N   . ILE A 1 30  ? 4.585   13.108  -26.912 1.00 45.25  ? 30  ILE H N   1 
ATOM   211  C CA  . ILE A 1 30  ? 3.994   11.775  -26.925 1.00 42.11  ? 30  ILE H CA  1 
ATOM   212  C C   . ILE A 1 30  ? 3.099   11.557  -28.138 1.00 41.50  ? 30  ILE H C   1 
ATOM   213  O O   . ILE A 1 30  ? 2.795   10.410  -28.485 1.00 42.51  ? 30  ILE H O   1 
ATOM   214  C CB  . ILE A 1 30  ? 3.212   11.547  -25.611 1.00 41.23  ? 30  ILE H CB  1 
ATOM   215  C CG1 . ILE A 1 30  ? 2.938   10.059  -25.380 1.00 31.56  ? 30  ILE H CG1 1 
ATOM   216  C CG2 . ILE A 1 30  ? 1.913   12.333  -25.618 1.00 37.70  ? 30  ILE H CG2 1 
ATOM   217  C CD1 . ILE A 1 30  ? 4.050   9.338   -24.652 1.00 46.22  ? 30  ILE H CD1 1 
ATOM   218  N N   . MET A 1 31  ? 2.675   12.629  -28.803 1.00 37.44  ? 31  MET H N   1 
ATOM   219  C CA  . MET A 1 31  ? 1.758   12.537  -29.929 1.00 31.56  ? 31  MET H CA  1 
ATOM   220  C C   . MET A 1 31  ? 2.438   12.727  -31.277 1.00 39.10  ? 31  MET H C   1 
ATOM   221  O O   . MET A 1 31  ? 1.753   12.719  -32.305 1.00 44.84  ? 31  MET H O   1 
ATOM   222  C CB  . MET A 1 31  ? 0.649   13.576  -29.780 1.00 40.85  ? 31  MET H CB  1 
ATOM   223  C CG  . MET A 1 31  ? 1.135   14.977  -30.058 1.00 53.95  ? 31  MET H CG  1 
ATOM   224  S SD  . MET A 1 31  ? -0.046  16.235  -29.580 1.00 62.56  ? 31  MET H SD  1 
ATOM   225  C CE  . MET A 1 31  ? 0.748   17.683  -30.263 1.00 45.13  ? 31  MET H CE  1 
ATOM   226  N N   . TYR A 1 32  ? 3.756   12.902  -31.305 1.00 42.83  ? 32  TYR H N   1 
ATOM   227  C CA  . TYR A 1 32  ? 4.465   13.178  -32.547 1.00 41.22  ? 32  TYR H CA  1 
ATOM   228  C C   . TYR A 1 32  ? 4.969   11.876  -33.157 1.00 38.47  ? 32  TYR H C   1 
ATOM   229  O O   . TYR A 1 32  ? 5.741   11.144  -32.528 1.00 31.99  ? 32  TYR H O   1 
ATOM   230  C CB  . TYR A 1 32  ? 5.621   14.149  -32.311 1.00 29.95  ? 32  TYR H CB  1 
ATOM   231  C CG  . TYR A 1 32  ? 5.235   15.598  -32.503 1.00 31.28  ? 32  TYR H CG  1 
ATOM   232  C CD1 . TYR A 1 32  ? 4.686   16.333  -31.462 1.00 32.45  ? 32  TYR H CD1 1 
ATOM   233  C CD2 . TYR A 1 32  ? 5.410   16.228  -33.728 1.00 39.85  ? 32  TYR H CD2 1 
ATOM   234  C CE1 . TYR A 1 32  ? 4.325   17.655  -31.633 1.00 36.84  ? 32  TYR H CE1 1 
ATOM   235  C CE2 . TYR A 1 32  ? 5.053   17.551  -33.908 1.00 47.99  ? 32  TYR H CE2 1 
ATOM   236  C CZ  . TYR A 1 32  ? 4.512   18.260  -32.857 1.00 52.02  ? 32  TYR H CZ  1 
ATOM   237  O OH  . TYR A 1 32  ? 4.155   19.578  -33.032 1.00 56.87  ? 32  TYR H OH  1 
ATOM   238  N N   . TRP A 1 33  ? 4.521   11.588  -34.377 1.00 46.81  ? 33  TRP H N   1 
ATOM   239  C CA  . TRP A 1 33  ? 5.041   10.463  -35.138 1.00 38.92  ? 33  TRP H CA  1 
ATOM   240  C C   . TRP A 1 33  ? 6.353   10.861  -35.802 1.00 40.65  ? 33  TRP H C   1 
ATOM   241  O O   . TRP A 1 33  ? 6.471   11.951  -36.368 1.00 44.70  ? 33  TRP H O   1 
ATOM   242  C CB  . TRP A 1 33  ? 4.035   10.018  -36.200 1.00 39.85  ? 33  TRP H CB  1 
ATOM   243  C CG  . TRP A 1 33  ? 2.749   9.459   -35.666 1.00 39.52  ? 33  TRP H CG  1 
ATOM   244  C CD1 . TRP A 1 33  ? 1.826   10.109  -34.902 1.00 47.38  ? 33  TRP H CD1 1 
ATOM   245  C CD2 . TRP A 1 33  ? 2.231   8.141   -35.884 1.00 42.21  ? 33  TRP H CD2 1 
ATOM   246  N NE1 . TRP A 1 33  ? 0.770   9.275   -34.621 1.00 48.28  ? 33  TRP H NE1 1 
ATOM   247  C CE2 . TRP A 1 33  ? 0.995   8.060   -35.213 1.00 41.21  ? 33  TRP H CE2 1 
ATOM   248  C CE3 . TRP A 1 33  ? 2.696   7.019   -36.577 1.00 41.55  ? 33  TRP H CE3 1 
ATOM   249  C CZ2 . TRP A 1 33  ? 0.220   6.903   -35.214 1.00 45.38  ? 33  TRP H CZ2 1 
ATOM   250  C CZ3 . TRP A 1 33  ? 1.926   5.871   -36.576 1.00 30.77  ? 33  TRP H CZ3 1 
ATOM   251  C CH2 . TRP A 1 33  ? 0.701   5.822   -35.900 1.00 42.84  ? 33  TRP H CH2 1 
ATOM   252  N N   . ILE A 1 34  ? 7.336   9.969   -35.739 1.00 37.63  ? 34  ILE H N   1 
ATOM   253  C CA  . ILE A 1 34  ? 8.685   10.246  -36.222 1.00 35.97  ? 34  ILE H CA  1 
ATOM   254  C C   . ILE A 1 34  ? 8.897   9.487   -37.524 1.00 34.26  ? 34  ILE H C   1 
ATOM   255  O O   . ILE A 1 34  ? 8.854   8.250   -37.546 1.00 35.33  ? 34  ILE H O   1 
ATOM   256  C CB  . ILE A 1 34  ? 9.747   9.861   -35.182 1.00 37.75  ? 34  ILE H CB  1 
ATOM   257  C CG1 . ILE A 1 34  ? 9.402   10.455  -33.814 1.00 29.50  ? 34  ILE H CG1 1 
ATOM   258  C CG2 . ILE A 1 34  ? 11.121  10.337  -35.629 1.00 45.62  ? 34  ILE H CG2 1 
ATOM   259  C CD1 . ILE A 1 34  ? 9.519   11.965  -33.753 1.00 33.12  ? 34  ILE H CD1 1 
ATOM   260  N N   . GLY A 1 35  ? 9.133   10.225  -38.606 1.00 34.23  ? 35  GLY H N   1 
ATOM   261  C CA  . GLY A 1 35  ? 9.433   9.621   -39.889 1.00 33.23  ? 35  GLY H CA  1 
ATOM   262  C C   . GLY A 1 35  ? 10.810  10.003  -40.391 1.00 40.03  ? 35  GLY H C   1 
ATOM   263  O O   . GLY A 1 35  ? 11.382  11.000  -39.941 1.00 52.90  ? 35  GLY H O   1 
ATOM   264  N N   . TRP A 1 36  ? 11.358  9.221   -41.318 1.00 34.14  ? 36  TRP H N   1 
ATOM   265  C CA  . TRP A 1 36  ? 12.683  9.464   -41.868 1.00 30.58  ? 36  TRP H CA  1 
ATOM   266  C C   . TRP A 1 36  ? 12.579  9.785   -43.351 1.00 31.23  ? 36  TRP H C   1 
ATOM   267  O O   . TRP A 1 36  ? 11.802  9.161   -44.080 1.00 43.14  ? 36  TRP H O   1 
ATOM   268  C CB  . TRP A 1 36  ? 13.604  8.259   -41.652 1.00 39.46  ? 36  TRP H CB  1 
ATOM   269  C CG  . TRP A 1 36  ? 14.035  8.091   -40.226 1.00 38.48  ? 36  TRP H CG  1 
ATOM   270  C CD1 . TRP A 1 36  ? 13.443  7.309   -39.277 1.00 31.92  ? 36  TRP H CD1 1 
ATOM   271  C CD2 . TRP A 1 36  ? 15.149  8.726   -39.584 1.00 33.51  ? 36  TRP H CD2 1 
ATOM   272  N NE1 . TRP A 1 36  ? 14.121  7.416   -38.086 1.00 37.16  ? 36  TRP H NE1 1 
ATOM   273  C CE2 . TRP A 1 36  ? 15.172  8.279   -38.248 1.00 42.70  ? 36  TRP H CE2 1 
ATOM   274  C CE3 . TRP A 1 36  ? 16.130  9.628   -40.011 1.00 33.42  ? 36  TRP H CE3 1 
ATOM   275  C CZ2 . TRP A 1 36  ? 16.136  8.703   -37.335 1.00 38.16  ? 36  TRP H CZ2 1 
ATOM   276  C CZ3 . TRP A 1 36  ? 17.087  10.047  -39.102 1.00 42.67  ? 36  TRP H CZ3 1 
ATOM   277  C CH2 . TRP A 1 36  ? 17.082  9.584   -37.780 1.00 42.59  ? 36  TRP H CH2 1 
ATOM   278  N N   . VAL A 1 37  ? 13.365  10.766  -43.789 1.00 26.45  ? 37  VAL H N   1 
ATOM   279  C CA  . VAL A 1 37  ? 13.372  11.229  -45.171 1.00 26.25  ? 37  VAL H CA  1 
ATOM   280  C C   . VAL A 1 37  ? 14.805  11.198  -45.684 1.00 34.05  ? 37  VAL H C   1 
ATOM   281  O O   . VAL A 1 37  ? 15.712  11.726  -45.032 1.00 36.74  ? 37  VAL H O   1 
ATOM   282  C CB  . VAL A 1 37  ? 12.780  12.646  -45.299 1.00 27.91  ? 37  VAL H CB  1 
ATOM   283  C CG1 . VAL A 1 37  ? 13.009  13.198  -46.697 1.00 32.25  ? 37  VAL H CG1 1 
ATOM   284  C CG2 . VAL A 1 37  ? 11.296  12.633  -44.966 1.00 30.19  ? 37  VAL H CG2 1 
ATOM   285  N N   . ARG A 1 38  ? 15.005  10.584  -46.848 1.00 33.31  ? 38  ARG H N   1 
ATOM   286  C CA  . ARG A 1 38  ? 16.312  10.502  -47.485 1.00 27.27  ? 38  ARG H CA  1 
ATOM   287  C C   . ARG A 1 38  ? 16.410  11.528  -48.606 1.00 31.52  ? 38  ARG H C   1 
ATOM   288  O O   . ARG A 1 38  ? 15.449  11.742  -49.351 1.00 36.89  ? 38  ARG H O   1 
ATOM   289  C CB  . ARG A 1 38  ? 16.567  9.098   -48.040 1.00 29.24  ? 38  ARG H CB  1 
ATOM   290  C CG  . ARG A 1 38  ? 17.917  8.941   -48.726 1.00 37.79  ? 38  ARG H CG  1 
ATOM   291  C CD  . ARG A 1 38  ? 18.177  7.505   -49.152 1.00 40.05  ? 38  ARG H CD  1 
ATOM   292  N NE  . ARG A 1 38  ? 17.495  7.165   -50.394 1.00 41.27  ? 38  ARG H NE  1 
ATOM   293  C CZ  . ARG A 1 38  ? 17.620  6.004   -51.023 1.00 41.11  ? 38  ARG H CZ  1 
ATOM   294  N NH1 . ARG A 1 38  ? 18.386  5.037   -50.543 1.00 29.40  ? 38  ARG H NH1 1 
ATOM   295  N NH2 . ARG A 1 38  ? 16.962  5.809   -52.162 1.00 42.84  ? 38  ARG H NH2 1 
ATOM   296  N N   . GLN A 1 39  ? 17.577  12.163  -48.721 1.00 38.29  ? 39  GLN H N   1 
ATOM   297  C CA  . GLN A 1 39  ? 17.832  13.140  -49.780 1.00 33.59  ? 39  GLN H CA  1 
ATOM   298  C C   . GLN A 1 39  ? 19.231  12.876  -50.330 1.00 40.36  ? 39  GLN H C   1 
ATOM   299  O O   . GLN A 1 39  ? 20.229  13.291  -49.732 1.00 42.59  ? 39  GLN H O   1 
ATOM   300  C CB  . GLN A 1 39  ? 17.695  14.568  -49.267 1.00 31.94  ? 39  GLN H CB  1 
ATOM   301  C CG  . GLN A 1 39  ? 17.752  15.623  -50.360 1.00 40.69  ? 39  GLN H CG  1 
ATOM   302  C CD  . GLN A 1 39  ? 17.480  17.021  -49.839 1.00 42.69  ? 39  GLN H CD  1 
ATOM   303  O OE1 . GLN A 1 39  ? 17.815  17.348  -48.701 1.00 45.61  ? 39  GLN H OE1 1 
ATOM   304  N NE2 . GLN A 1 39  ? 16.860  17.852  -50.670 1.00 43.61  ? 39  GLN H NE2 1 
ATOM   305  N N   . MET A 1 40  ? 19.294  12.183  -51.464 1.00 55.35  ? 40  MET H N   1 
ATOM   306  C CA  . MET A 1 40  ? 20.564  11.881  -52.099 1.00 46.68  ? 40  MET H CA  1 
ATOM   307  C C   . MET A 1 40  ? 21.185  13.156  -52.670 1.00 44.64  ? 40  MET H C   1 
ATOM   308  O O   . MET A 1 40  ? 20.478  14.127  -52.952 1.00 48.71  ? 40  MET H O   1 
ATOM   309  C CB  . MET A 1 40  ? 20.364  10.825  -53.185 1.00 42.33  ? 40  MET H CB  1 
ATOM   310  C CG  . MET A 1 40  ? 19.908  9.479   -52.629 1.00 53.01  ? 40  MET H CG  1 
ATOM   311  S SD  . MET A 1 40  ? 19.896  8.135   -53.832 1.00 44.01  ? 40  MET H SD  1 
ATOM   312  C CE  . MET A 1 40  ? 18.477  8.571   -54.832 1.00 45.19  ? 40  MET H CE  1 
ATOM   313  N N   . PRO A 1 41  ? 22.527  13.184  -52.827 1.00 45.09  ? 41  PRO H N   1 
ATOM   314  C CA  . PRO A 1 41  ? 23.205  14.427  -53.230 1.00 31.86  ? 41  PRO H CA  1 
ATOM   315  C C   . PRO A 1 41  ? 22.643  15.067  -54.489 1.00 32.33  ? 41  PRO H C   1 
ATOM   316  O O   . PRO A 1 41  ? 22.711  14.494  -55.581 1.00 33.61  ? 41  PRO H O   1 
ATOM   317  C CB  . PRO A 1 41  ? 24.656  13.978  -53.445 1.00 29.80  ? 41  PRO H CB  1 
ATOM   318  C CG  . PRO A 1 41  ? 24.815  12.806  -52.556 1.00 38.45  ? 41  PRO H CG  1 
ATOM   319  C CD  . PRO A 1 41  ? 23.489  12.098  -52.569 1.00 46.16  ? 41  PRO H CD  1 
ATOM   320  N N   . GLY A 1 42  ? 22.083  16.264  -54.334 1.00 38.14  ? 42  GLY H N   1 
ATOM   321  C CA  . GLY A 1 42  ? 21.588  17.038  -55.449 1.00 35.12  ? 42  GLY H CA  1 
ATOM   322  C C   . GLY A 1 42  ? 20.196  16.689  -55.922 1.00 31.78  ? 42  GLY H C   1 
ATOM   323  O O   . GLY A 1 42  ? 19.689  17.355  -56.833 1.00 51.56  ? 42  GLY H O   1 
ATOM   324  N N   . LYS A 1 43  ? 19.555  15.681  -55.340 1.00 45.22  ? 43  LYS H N   1 
ATOM   325  C CA  . LYS A 1 43  ? 18.232  15.258  -55.769 1.00 52.74  ? 43  LYS H CA  1 
ATOM   326  C C   . LYS A 1 43  ? 17.209  15.516  -54.662 1.00 38.53  ? 43  LYS H C   1 
ATOM   327  O O   . LYS A 1 43  ? 17.520  16.101  -53.617 1.00 37.83  ? 43  LYS H O   1 
ATOM   328  C CB  . LYS A 1 43  ? 18.267  13.790  -56.207 1.00 40.64  ? 43  LYS H CB  1 
ATOM   329  C CG  . LYS A 1 43  ? 19.168  13.530  -57.414 1.00 52.23  ? 43  LYS H CG  1 
ATOM   330  C CD  . LYS A 1 43  ? 19.061  14.646  -58.452 1.00 71.10  ? 43  LYS H CD  1 
ATOM   331  C CE  . LYS A 1 43  ? 20.353  14.782  -59.251 1.00 75.31  ? 43  LYS H CE  1 
ATOM   332  N NZ  . LYS A 1 43  ? 20.545  16.160  -59.793 1.00 54.17  ? 43  LYS H NZ  1 
ATOM   333  N N   . GLY A 1 44  ? 15.976  15.074  -54.894 1.00 28.78  ? 44  GLY H N   1 
ATOM   334  C CA  . GLY A 1 44  ? 14.849  15.461  -54.072 1.00 36.27  ? 44  GLY H CA  1 
ATOM   335  C C   . GLY A 1 44  ? 14.691  14.644  -52.806 1.00 32.63  ? 44  GLY H C   1 
ATOM   336  O O   . GLY A 1 44  ? 15.611  13.968  -52.338 1.00 44.49  ? 44  GLY H O   1 
ATOM   337  N N   . LEU A 1 45  ? 13.486  14.714  -52.248 1.00 31.67  ? 45  LEU H N   1 
ATOM   338  C CA  . LEU A 1 45  ? 13.166  14.113  -50.962 1.00 34.14  ? 45  LEU H CA  1 
ATOM   339  C C   . LEU A 1 45  ? 12.428  12.796  -51.161 1.00 38.85  ? 45  LEU H C   1 
ATOM   340  O O   . LEU A 1 45  ? 11.508  12.705  -51.979 1.00 46.53  ? 45  LEU H O   1 
ATOM   341  C CB  . LEU A 1 45  ? 12.313  15.064  -50.121 1.00 40.00  ? 45  LEU H CB  1 
ATOM   342  C CG  . LEU A 1 45  ? 12.881  16.467  -49.894 1.00 40.70  ? 45  LEU H CG  1 
ATOM   343  C CD1 . LEU A 1 45  ? 11.864  17.353  -49.195 1.00 32.50  ? 45  LEU H CD1 1 
ATOM   344  C CD2 . LEU A 1 45  ? 14.170  16.395  -49.092 1.00 47.52  ? 45  LEU H CD2 1 
ATOM   345  N N   . GLU A 1 46  ? 12.839  11.779  -50.406 1.00 34.20  ? 46  GLU H N   1 
ATOM   346  C CA  . GLU A 1 46  ? 12.216  10.464  -50.444 1.00 32.28  ? 46  GLU H CA  1 
ATOM   347  C C   . GLU A 1 46  ? 11.786  10.087  -49.035 1.00 34.89  ? 46  GLU H C   1 
ATOM   348  O O   . GLU A 1 46  ? 12.579  10.193  -48.095 1.00 35.35  ? 46  GLU H O   1 
ATOM   349  C CB  . GLU A 1 46  ? 13.178  9.409   -51.001 1.00 39.97  ? 46  GLU H CB  1 
ATOM   350  C CG  . GLU A 1 46  ? 14.066  9.912   -52.124 1.00 56.64  ? 46  GLU H CG  1 
ATOM   351  C CD  . GLU A 1 46  ? 15.205  8.960   -52.430 1.00 60.40  ? 46  GLU H CD  1 
ATOM   352  O OE1 . GLU A 1 46  ? 14.942  7.752   -52.611 1.00 56.24  ? 46  GLU H OE1 1 
ATOM   353  O OE2 . GLU A 1 46  ? 16.365  9.421   -52.477 1.00 55.90  ? 46  GLU H OE2 1 
ATOM   354  N N   . TRP A 1 47  ? 10.540  9.646   -48.891 1.00 29.77  ? 47  TRP H N   1 
ATOM   355  C CA  . TRP A 1 47  ? 10.008  9.242   -47.596 1.00 35.45  ? 47  TRP H CA  1 
ATOM   356  C C   . TRP A 1 47  ? 10.318  7.767   -47.367 1.00 32.81  ? 47  TRP H C   1 
ATOM   357  O O   . TRP A 1 47  ? 9.911   6.910   -48.160 1.00 42.09  ? 47  TRP H O   1 
ATOM   358  C CB  . TRP A 1 47  ? 8.504   9.503   -47.527 1.00 36.94  ? 47  TRP H CB  1 
ATOM   359  C CG  . TRP A 1 47  ? 7.903   9.240   -46.179 1.00 34.34  ? 47  TRP H CG  1 
ATOM   360  C CD1 . TRP A 1 47  ? 7.936   10.063  -45.091 1.00 35.86  ? 47  TRP H CD1 1 
ATOM   361  C CD2 . TRP A 1 47  ? 7.166   8.078   -45.780 1.00 38.38  ? 47  TRP H CD2 1 
ATOM   362  N NE1 . TRP A 1 47  ? 7.271   9.483   -44.037 1.00 37.57  ? 47  TRP H NE1 1 
ATOM   363  C CE2 . TRP A 1 47  ? 6.788   8.264   -44.436 1.00 35.98  ? 47  TRP H CE2 1 
ATOM   364  C CE3 . TRP A 1 47  ? 6.791   6.896   -46.428 1.00 42.64  ? 47  TRP H CE3 1 
ATOM   365  C CZ2 . TRP A 1 47  ? 6.053   7.315   -43.729 1.00 39.47  ? 47  TRP H CZ2 1 
ATOM   366  C CZ3 . TRP A 1 47  ? 6.064   5.955   -45.723 1.00 42.61  ? 47  TRP H CZ3 1 
ATOM   367  C CH2 . TRP A 1 47  ? 5.702   6.170   -44.388 1.00 46.42  ? 47  TRP H CH2 1 
ATOM   368  N N   . MET A 1 48  ? 11.036  7.476   -46.284 1.00 29.23  ? 48  MET H N   1 
ATOM   369  C CA  . MET A 1 48  ? 11.501  6.125   -45.997 1.00 39.42  ? 48  MET H CA  1 
ATOM   370  C C   . MET A 1 48  ? 10.501  5.331   -45.162 1.00 45.48  ? 48  MET H C   1 
ATOM   371  O O   . MET A 1 48  ? 10.209  4.172   -45.472 1.00 41.07  ? 48  MET H O   1 
ATOM   372  C CB  . MET A 1 48  ? 12.850  6.182   -45.276 1.00 29.35  ? 48  MET H CB  1 
ATOM   373  C CG  . MET A 1 48  ? 13.881  7.068   -45.951 1.00 33.56  ? 48  MET H CG  1 
ATOM   374  S SD  . MET A 1 48  ? 15.467  6.970   -45.109 1.00 46.71  ? 48  MET H SD  1 
ATOM   375  C CE  . MET A 1 48  ? 15.637  5.194   -44.965 1.00 26.03  ? 48  MET H CE  1 
ATOM   376  N N   . GLY A 1 49  ? 9.981   5.937   -44.103 1.00 48.93  ? 49  GLY H N   1 
ATOM   377  C CA  . GLY A 1 49  ? 9.065   5.239   -43.225 1.00 43.75  ? 49  GLY H CA  1 
ATOM   378  C C   . GLY A 1 49  ? 8.645   6.138   -42.085 1.00 35.21  ? 49  GLY H C   1 
ATOM   379  O O   . GLY A 1 49  ? 8.958   7.330   -42.060 1.00 44.02  ? 49  GLY H O   1 
ATOM   380  N N   . ILE A 1 50  ? 7.920   5.546   -41.137 1.00 33.03  ? 50  ILE H N   1 
ATOM   381  C CA  . ILE A 1 50  ? 7.429   6.277   -39.977 1.00 32.02  ? 50  ILE H CA  1 
ATOM   382  C C   . ILE A 1 50  ? 7.290   5.308   -38.813 1.00 31.50  ? 50  ILE H C   1 
ATOM   383  O O   . ILE A 1 50  ? 7.129   4.100   -39.002 1.00 36.93  ? 50  ILE H O   1 
ATOM   384  C CB  . ILE A 1 50  ? 6.088   6.983   -40.273 1.00 30.36  ? 50  ILE H CB  1 
ATOM   385  C CG1 . ILE A 1 50  ? 5.891   8.146   -39.305 1.00 40.53  ? 50  ILE H CG1 1 
ATOM   386  C CG2 . ILE A 1 50  ? 4.923   5.994   -40.195 1.00 31.85  ? 50  ILE H CG2 1 
ATOM   387  C CD1 . ILE A 1 50  ? 4.556   8.834   -39.455 1.00 42.89  ? 50  ILE H CD1 1 
ATOM   388  N N   . ILE A 1 51  ? 7.370   5.847   -37.599 1.00 32.44  ? 51  ILE H N   1 
ATOM   389  C CA  . ILE A 1 51  ? 7.183   5.055   -36.389 1.00 32.97  ? 51  ILE H CA  1 
ATOM   390  C C   . ILE A 1 51  ? 6.539   5.932   -35.327 1.00 38.59  ? 51  ILE H C   1 
ATOM   391  O O   . ILE A 1 51  ? 6.894   7.104   -35.169 1.00 42.70  ? 51  ILE H O   1 
ATOM   392  C CB  . ILE A 1 51  ? 8.513   4.454   -35.885 1.00 29.76  ? 51  ILE H CB  1 
ATOM   393  C CG1 . ILE A 1 51  ? 8.289   3.701   -34.572 1.00 27.33  ? 51  ILE H CG1 1 
ATOM   394  C CG2 . ILE A 1 51  ? 9.561   5.543   -35.707 1.00 27.64  ? 51  ILE H CG2 1 
ATOM   395  C CD1 . ILE A 1 51  ? 9.197   2.508   -34.386 1.00 38.99  ? 51  ILE H CD1 1 
ATOM   396  N N   . TYR A 1 52  ? 5.578   5.360   -34.602 1.00 41.91  ? 52  TYR H N   1 
ATOM   397  C CA  . TYR A 1 52  ? 5.012   6.025   -33.440 1.00 39.68  ? 52  TYR H CA  1 
ATOM   398  C C   . TYR A 1 52  ? 5.742   5.528   -32.203 1.00 40.62  ? 52  TYR H C   1 
ATOM   399  O O   . TYR A 1 52  ? 5.602   4.348   -31.845 1.00 33.24  ? 52  TYR H O   1 
ATOM   400  C CB  . TYR A 1 52  ? 3.515   5.751   -33.328 1.00 36.82  ? 52  TYR H CB  1 
ATOM   401  C CG  . TYR A 1 52  ? 2.877   6.414   -32.133 1.00 41.35  ? 52  TYR H CG  1 
ATOM   402  C CD1 . TYR A 1 52  ? 2.577   7.770   -32.145 1.00 42.78  ? 52  TYR H CD1 1 
ATOM   403  C CD2 . TYR A 1 52  ? 2.580   5.687   -30.989 1.00 42.39  ? 52  TYR H CD2 1 
ATOM   404  C CE1 . TYR A 1 52  ? 1.998   8.382   -31.052 1.00 43.12  ? 52  TYR H CE1 1 
ATOM   405  C CE2 . TYR A 1 52  ? 1.998   6.290   -29.892 1.00 44.54  ? 52  TYR H CE2 1 
ATOM   406  C CZ  . TYR A 1 52  ? 1.711   7.637   -29.928 1.00 43.81  ? 52  TYR H CZ  1 
ATOM   407  O OH  . TYR A 1 52  ? 1.135   8.238   -28.834 1.00 40.65  ? 52  TYR H OH  1 
ATOM   408  N N   . PRO A 1 53  A 6.518   6.374   -31.521 1.00 40.50  ? 52  PRO H N   1 
ATOM   409  C CA  . PRO A 1 53  A 7.374   5.877   -30.429 1.00 35.80  ? 52  PRO H CA  1 
ATOM   410  C C   . PRO A 1 53  A 6.614   5.281   -29.255 1.00 39.56  ? 52  PRO H C   1 
ATOM   411  O O   . PRO A 1 53  A 7.213   4.534   -28.471 1.00 49.00  ? 52  PRO H O   1 
ATOM   412  C CB  . PRO A 1 53  A 8.161   7.127   -30.007 1.00 43.38  ? 52  PRO H CB  1 
ATOM   413  C CG  . PRO A 1 53  A 8.091   8.045   -31.187 1.00 40.69  ? 52  PRO H CG  1 
ATOM   414  C CD  . PRO A 1 53  A 6.748   7.801   -31.800 1.00 39.91  ? 52  PRO H CD  1 
ATOM   415  N N   . GLY A 1 54  ? 5.324   5.587   -29.101 1.00 43.00  ? 53  GLY H N   1 
ATOM   416  C CA  . GLY A 1 54  ? 4.590   5.090   -27.947 1.00 42.85  ? 53  GLY H CA  1 
ATOM   417  C C   . GLY A 1 54  ? 4.493   3.578   -27.916 1.00 46.82  ? 53  GLY H C   1 
ATOM   418  O O   . GLY A 1 54  ? 4.605   2.960   -26.854 1.00 48.45  ? 53  GLY H O   1 
ATOM   419  N N   . ASP A 1 55  ? 4.294   2.959   -29.081 1.00 46.95  ? 54  ASP H N   1 
ATOM   420  C CA  . ASP A 1 55  ? 4.129   1.513   -29.160 1.00 48.10  ? 54  ASP H CA  1 
ATOM   421  C C   . ASP A 1 55  ? 4.957   0.885   -30.274 1.00 51.78  ? 54  ASP H C   1 
ATOM   422  O O   . ASP A 1 55  ? 4.759   -0.296  -30.584 1.00 34.65  ? 54  ASP H O   1 
ATOM   423  C CB  . ASP A 1 55  ? 2.646   1.153   -29.333 1.00 43.84  ? 54  ASP H CB  1 
ATOM   424  C CG  . ASP A 1 55  ? 2.048   1.682   -30.630 1.00 52.63  ? 54  ASP H CG  1 
ATOM   425  O OD1 . ASP A 1 55  ? 0.845   1.436   -30.861 1.00 56.62  ? 54  ASP H OD1 1 
ATOM   426  O OD2 . ASP A 1 55  ? 2.772   2.326   -31.421 1.00 62.03  ? 54  ASP H OD2 1 
ATOM   427  N N   . SER A 1 56  ? 5.880   1.645   -30.869 1.00 49.60  ? 55  SER H N   1 
ATOM   428  C CA  . SER A 1 56  ? 6.710   1.181   -31.979 1.00 45.63  ? 55  SER H CA  1 
ATOM   429  C C   . SER A 1 56  ? 5.860   0.740   -33.169 1.00 43.74  ? 55  SER H C   1 
ATOM   430  O O   . SER A 1 56  ? 6.146   -0.267  -33.819 1.00 53.91  ? 55  SER H O   1 
ATOM   431  C CB  . SER A 1 56  ? 7.657   0.061   -31.539 1.00 36.06  ? 55  SER H CB  1 
ATOM   432  O OG  . SER A 1 56  ? 8.617   0.538   -30.612 1.00 46.42  ? 55  SER H OG  1 
ATOM   433  N N   . ASP A 1 57  ? 4.806   1.501   -33.458 1.00 46.68  ? 56  ASP H N   1 
ATOM   434  C CA  . ASP A 1 57  ? 4.002   1.293   -34.662 1.00 40.96  ? 56  ASP H CA  1 
ATOM   435  C C   . ASP A 1 57  ? 4.830   1.728   -35.863 1.00 37.44  ? 56  ASP H C   1 
ATOM   436  O O   . ASP A 1 57  ? 4.909   2.916   -36.179 1.00 37.85  ? 56  ASP H O   1 
ATOM   437  C CB  . ASP A 1 57  ? 2.698   2.081   -34.572 1.00 46.28  ? 56  ASP H CB  1 
ATOM   438  C CG  . ASP A 1 57  ? 1.724   1.757   -35.700 1.00 44.87  ? 56  ASP H CG  1 
ATOM   439  O OD1 . ASP A 1 57  ? 2.154   1.247   -36.756 1.00 52.86  ? 56  ASP H OD1 1 
ATOM   440  O OD2 . ASP A 1 57  ? 0.515   2.024   -35.527 1.00 36.20  ? 56  ASP H OD2 1 
ATOM   441  N N   . THR A 1 58  ? 5.439   0.766   -36.550 1.00 35.47  ? 57  THR H N   1 
ATOM   442  C CA  . THR A 1 58  ? 6.359   1.049   -37.644 1.00 39.99  ? 57  THR H CA  1 
ATOM   443  C C   . THR A 1 58  ? 5.686   0.771   -38.980 1.00 34.28  ? 57  THR H C   1 
ATOM   444  O O   . THR A 1 58  ? 5.081   -0.289  -39.168 1.00 36.47  ? 57  THR H O   1 
ATOM   445  C CB  . THR A 1 58  ? 7.630   0.209   -37.521 1.00 45.57  ? 57  THR H CB  1 
ATOM   446  O OG1 . THR A 1 58  ? 7.993   0.086   -36.141 1.00 44.95  ? 57  THR H OG1 1 
ATOM   447  C CG2 . THR A 1 58  ? 8.769   0.872   -38.279 1.00 36.13  ? 57  THR H CG2 1 
ATOM   448  N N   . ARG A 1 59  ? 5.789   1.727   -39.902 1.00 33.34  ? 58  ARG H N   1 
ATOM   449  C CA  . ARG A 1 59  ? 5.251   1.587   -41.250 1.00 40.61  ? 58  ARG H CA  1 
ATOM   450  C C   . ARG A 1 59  ? 6.314   2.036   -42.242 1.00 36.53  ? 58  ARG H C   1 
ATOM   451  O O   . ARG A 1 59  ? 6.804   3.167   -42.158 1.00 36.54  ? 58  ARG H O   1 
ATOM   452  C CB  . ARG A 1 59  ? 3.965   2.403   -41.417 1.00 40.01  ? 58  ARG H CB  1 
ATOM   453  C CG  . ARG A 1 59  ? 2.948   2.161   -40.308 1.00 44.86  ? 58  ARG H CG  1 
ATOM   454  C CD  . ARG A 1 59  ? 1.629   2.870   -40.564 1.00 44.36  ? 58  ARG H CD  1 
ATOM   455  N NE  . ARG A 1 59  ? 0.716   2.717   -39.437 1.00 26.40  ? 58  ARG H NE  1 
ATOM   456  C CZ  . ARG A 1 59  ? -0.557  3.088   -39.445 1.00 35.64  ? 58  ARG H CZ  1 
ATOM   457  N NH1 . ARG A 1 59  ? -1.113  3.629   -40.517 1.00 45.95  ? 58  ARG H NH1 1 
ATOM   458  N NH2 . ARG A 1 59  ? -1.293  2.908   -38.351 1.00 32.92  ? 58  ARG H NH2 1 
ATOM   459  N N   . TYR A 1 60  ? 6.662   1.159   -43.178 1.00 37.28  ? 59  TYR H N   1 
ATOM   460  C CA  . TYR A 1 60  ? 7.742   1.404   -44.122 1.00 36.68  ? 59  TYR H CA  1 
ATOM   461  C C   . TYR A 1 60  ? 7.200   1.751   -45.501 1.00 37.97  ? 59  TYR H C   1 
ATOM   462  O O   . TYR A 1 60  ? 6.119   1.309   -45.897 1.00 44.23  ? 59  TYR H O   1 
ATOM   463  C CB  . TYR A 1 60  ? 8.655   0.182   -44.241 1.00 33.28  ? 59  TYR H CB  1 
ATOM   464  C CG  . TYR A 1 60  ? 9.488   -0.105  -43.017 1.00 31.18  ? 59  TYR H CG  1 
ATOM   465  C CD1 . TYR A 1 60  ? 10.741  0.472   -42.857 1.00 39.86  ? 59  TYR H CD1 1 
ATOM   466  C CD2 . TYR A 1 60  ? 9.030   -0.963  -42.028 1.00 28.31  ? 59  TYR H CD2 1 
ATOM   467  C CE1 . TYR A 1 60  ? 11.510  0.208   -41.741 1.00 39.33  ? 59  TYR H CE1 1 
ATOM   468  C CE2 . TYR A 1 60  ? 9.794   -1.234  -40.910 1.00 35.29  ? 59  TYR H CE2 1 
ATOM   469  C CZ  . TYR A 1 60  ? 11.031  -0.645  -40.771 1.00 32.16  ? 59  TYR H CZ  1 
ATOM   470  O OH  . TYR A 1 60  ? 11.793  -0.910  -39.657 1.00 42.64  ? 59  TYR H OH  1 
ATOM   471  N N   . SER A 1 61  ? 7.963   2.558   -46.229 1.00 39.71  ? 60  SER H N   1 
ATOM   472  C CA  . SER A 1 61  ? 7.712   2.714   -47.651 1.00 43.57  ? 60  SER H CA  1 
ATOM   473  C C   . SER A 1 61  ? 8.114   1.433   -48.379 1.00 55.67  ? 60  SER H C   1 
ATOM   474  O O   . SER A 1 61  ? 9.107   0.796   -48.009 1.00 60.91  ? 60  SER H O   1 
ATOM   475  C CB  . SER A 1 61  ? 8.489   3.905   -48.211 1.00 44.61  ? 60  SER H CB  1 
ATOM   476  O OG  . SER A 1 61  ? 8.376   3.973   -49.622 1.00 43.27  ? 60  SER H OG  1 
ATOM   477  N N   . PRO A 1 62  ? 7.363   1.024   -49.404 1.00 50.48  ? 61  PRO H N   1 
ATOM   478  C CA  . PRO A 1 62  ? 7.716   -0.217  -50.115 1.00 54.42  ? 61  PRO H CA  1 
ATOM   479  C C   . PRO A 1 62  ? 9.115   -0.199  -50.703 1.00 48.81  ? 61  PRO H C   1 
ATOM   480  O O   . PRO A 1 62  ? 9.763   -1.252  -50.770 1.00 53.66  ? 61  PRO H O   1 
ATOM   481  C CB  . PRO A 1 62  ? 6.642   -0.307  -51.209 1.00 59.98  ? 61  PRO H CB  1 
ATOM   482  C CG  . PRO A 1 62  ? 5.490   0.476   -50.670 1.00 43.51  ? 61  PRO H CG  1 
ATOM   483  C CD  . PRO A 1 62  ? 6.101   1.605   -49.891 1.00 45.92  ? 61  PRO H CD  1 
ATOM   484  N N   . SER A 1 63  ? 9.602   0.968   -51.129 1.00 44.13  ? 62  SER H N   1 
ATOM   485  C CA  . SER A 1 63  ? 10.947  1.051   -51.689 1.00 47.68  ? 62  SER H CA  1 
ATOM   486  C C   . SER A 1 63  ? 12.012  0.731   -50.647 1.00 43.28  ? 62  SER H C   1 
ATOM   487  O O   . SER A 1 63  ? 13.074  0.198   -50.989 1.00 43.48  ? 62  SER H O   1 
ATOM   488  C CB  . SER A 1 63  ? 11.185  2.441   -52.278 1.00 55.09  ? 62  SER H CB  1 
ATOM   489  O OG  . SER A 1 63  ? 10.174  2.780   -53.212 1.00 44.73  ? 62  SER H OG  1 
ATOM   490  N N   . PHE A 1 64  ? 11.751  1.046   -49.379 1.00 38.92  ? 63  PHE H N   1 
ATOM   491  C CA  . PHE A 1 64  ? 12.714  0.839   -48.306 1.00 33.44  ? 63  PHE H CA  1 
ATOM   492  C C   . PHE A 1 64  ? 12.357  -0.323  -47.391 1.00 39.75  ? 63  PHE H C   1 
ATOM   493  O O   . PHE A 1 64  ? 13.108  -0.602  -46.450 1.00 46.05  ? 63  PHE H O   1 
ATOM   494  C CB  . PHE A 1 64  ? 12.860  2.121   -47.478 1.00 43.82  ? 63  PHE H CB  1 
ATOM   495  C CG  . PHE A 1 64  ? 13.414  3.278   -48.253 1.00 39.68  ? 63  PHE H CG  1 
ATOM   496  C CD1 . PHE A 1 64  ? 12.575  4.118   -48.966 1.00 32.30  ? 63  PHE H CD1 1 
ATOM   497  C CD2 . PHE A 1 64  ? 14.777  3.523   -48.274 1.00 26.24  ? 63  PHE H CD2 1 
ATOM   498  C CE1 . PHE A 1 64  ? 13.085  5.183   -49.682 1.00 46.35  ? 63  PHE H CE1 1 
ATOM   499  C CE2 . PHE A 1 64  ? 15.293  4.585   -48.988 1.00 29.64  ? 63  PHE H CE2 1 
ATOM   500  C CZ  . PHE A 1 64  ? 14.446  5.417   -49.694 1.00 44.03  ? 63  PHE H CZ  1 
ATOM   501  N N   . GLN A 1 65  ? 11.239  -1.003  -47.635 1.00 47.63  ? 64  GLN H N   1 
ATOM   502  C CA  . GLN A 1 65  ? 10.862  -2.150  -46.818 1.00 47.68  ? 64  GLN H CA  1 
ATOM   503  C C   . GLN A 1 65  ? 11.905  -3.253  -46.947 1.00 50.61  ? 64  GLN H C   1 
ATOM   504  O O   . GLN A 1 65  ? 12.172  -3.742  -48.049 1.00 53.00  ? 64  GLN H O   1 
ATOM   505  C CB  . GLN A 1 65  ? 9.486   -2.663  -47.242 1.00 51.69  ? 64  GLN H CB  1 
ATOM   506  C CG  . GLN A 1 65  ? 9.050   -3.945  -46.546 1.00 62.91  ? 64  GLN H CG  1 
ATOM   507  C CD  . GLN A 1 65  ? 8.452   -3.697  -45.176 1.00 55.14  ? 64  GLN H CD  1 
ATOM   508  O OE1 . GLN A 1 65  ? 9.063   -4.008  -44.152 1.00 59.35  ? 64  GLN H OE1 1 
ATOM   509  N NE2 . GLN A 1 65  ? 7.244   -3.144  -45.150 1.00 32.55  ? 64  GLN H NE2 1 
ATOM   510  N N   . GLY A 1 66  ? 12.498  -3.640  -45.818 1.00 42.95  ? 65  GLY H N   1 
ATOM   511  C CA  . GLY A 1 66  ? 13.511  -4.671  -45.795 1.00 36.62  ? 65  GLY H CA  1 
ATOM   512  C C   . GLY A 1 66  ? 14.929  -4.185  -46.001 1.00 45.53  ? 65  GLY H C   1 
ATOM   513  O O   . GLY A 1 66  ? 15.870  -4.951  -45.756 1.00 62.17  ? 65  GLY H O   1 
ATOM   514  N N   . GLN A 1 67  ? 15.115  -2.941  -46.442 1.00 34.99  ? 66  GLN H N   1 
ATOM   515  C CA  . GLN A 1 67  ? 16.451  -2.386  -46.616 1.00 39.74  ? 66  GLN H CA  1 
ATOM   516  C C   . GLN A 1 67  ? 16.954  -1.682  -45.365 1.00 41.00  ? 66  GLN H C   1 
ATOM   517  O O   . GLN A 1 67  ? 18.159  -1.709  -45.089 1.00 49.22  ? 66  GLN H O   1 
ATOM   518  C CB  . GLN A 1 67  ? 16.466  -1.406  -47.794 1.00 55.95  ? 66  GLN H CB  1 
ATOM   519  C CG  . GLN A 1 67  ? 16.006  -2.002  -49.120 1.00 60.57  ? 66  GLN H CG  1 
ATOM   520  C CD  . GLN A 1 67  ? 17.013  -2.969  -49.716 1.00 69.62  ? 66  GLN H CD  1 
ATOM   521  O OE1 . GLN A 1 67  ? 17.212  -4.073  -49.207 1.00 75.92  ? 66  GLN H OE1 1 
ATOM   522  N NE2 . GLN A 1 67  ? 17.655  -2.557  -50.804 1.00 72.93  ? 66  GLN H NE2 1 
ATOM   523  N N   . VAL A 1 68  ? 16.057  -1.054  -44.606 1.00 45.88  ? 67  VAL H N   1 
ATOM   524  C CA  . VAL A 1 68  ? 16.397  -0.375  -43.366 1.00 34.97  ? 67  VAL H CA  1 
ATOM   525  C C   . VAL A 1 68  ? 15.431  -0.840  -42.286 1.00 37.82  ? 67  VAL H C   1 
ATOM   526  O O   . VAL A 1 68  ? 14.329  -1.318  -42.566 1.00 43.63  ? 67  VAL H O   1 
ATOM   527  C CB  . VAL A 1 68  ? 16.345  1.163   -43.500 1.00 40.64  ? 67  VAL H CB  1 
ATOM   528  C CG1 . VAL A 1 68  ? 17.218  1.629   -44.647 1.00 42.59  ? 67  VAL H CG1 1 
ATOM   529  C CG2 . VAL A 1 68  ? 14.910  1.634   -43.696 1.00 36.28  ? 67  VAL H CG2 1 
ATOM   530  N N   . THR A 1 69  ? 15.863  -0.701  -41.037 1.00 43.44  ? 68  THR H N   1 
ATOM   531  C CA  . THR A 1 69  ? 15.024  -0.982  -39.881 1.00 47.05  ? 68  THR H CA  1 
ATOM   532  C C   . THR A 1 69  ? 14.831  0.305   -39.094 1.00 46.93  ? 68  THR H C   1 
ATOM   533  O O   . THR A 1 69  ? 15.808  0.961   -38.717 1.00 49.10  ? 68  THR H O   1 
ATOM   534  C CB  . THR A 1 69  ? 15.637  -2.069  -38.990 1.00 45.16  ? 68  THR H CB  1 
ATOM   535  O OG1 . THR A 1 69  ? 15.616  -3.326  -39.677 1.00 48.27  ? 68  THR H OG1 1 
ATOM   536  C CG2 . THR A 1 69  ? 14.862  -2.193  -37.684 1.00 27.44  ? 68  THR H CG2 1 
ATOM   537  N N   . ILE A 1 70  ? 13.574  0.667   -38.860 1.00 40.17  ? 69  ILE H N   1 
ATOM   538  C CA  . ILE A 1 70  ? 13.221  1.855   -38.094 1.00 27.98  ? 69  ILE H CA  1 
ATOM   539  C C   . ILE A 1 70  ? 12.688  1.395   -36.746 1.00 38.17  ? 69  ILE H C   1 
ATOM   540  O O   . ILE A 1 70  ? 11.729  0.617   -36.681 1.00 42.51  ? 69  ILE H O   1 
ATOM   541  C CB  . ILE A 1 70  ? 12.190  2.723   -38.831 1.00 33.73  ? 69  ILE H CB  1 
ATOM   542  C CG1 . ILE A 1 70  ? 12.738  3.171   -40.186 1.00 41.97  ? 69  ILE H CG1 1 
ATOM   543  C CG2 . ILE A 1 70  ? 11.826  3.933   -37.993 1.00 34.43  ? 69  ILE H CG2 1 
ATOM   544  C CD1 . ILE A 1 70  ? 11.787  4.055   -40.964 1.00 24.43  ? 69  ILE H CD1 1 
ATOM   545  N N   . SER A 1 71  ? 13.315  1.869   -35.672 1.00 46.03  ? 70  SER H N   1 
ATOM   546  C CA  . SER A 1 71  ? 12.929  1.505   -34.318 1.00 36.73  ? 70  SER H CA  1 
ATOM   547  C C   . SER A 1 71  ? 12.906  2.765   -33.463 1.00 36.67  ? 70  SER H C   1 
ATOM   548  O O   . SER A 1 71  ? 13.192  3.869   -33.937 1.00 33.05  ? 70  SER H O   1 
ATOM   549  C CB  . SER A 1 71  ? 13.880  0.454   -33.735 1.00 32.92  ? 70  SER H CB  1 
ATOM   550  O OG  . SER A 1 71  ? 15.209  0.944   -33.690 1.00 52.15  ? 70  SER H OG  1 
ATOM   551  N N   . ALA A 1 72  ? 12.557  2.595   -32.191 1.00 42.98  ? 71  ALA H N   1 
ATOM   552  C CA  . ALA A 1 72  ? 12.542  3.706   -31.253 1.00 37.60  ? 71  ALA H CA  1 
ATOM   553  C C   . ALA A 1 72  ? 12.670  3.159   -29.840 1.00 42.13  ? 71  ALA H C   1 
ATOM   554  O O   . ALA A 1 72  ? 12.420  1.978   -29.585 1.00 47.54  ? 71  ALA H O   1 
ATOM   555  C CB  . ALA A 1 72  ? 11.269  4.548   -31.394 1.00 39.66  ? 71  ALA H CB  1 
ATOM   556  N N   . ASP A 1 73  ? 13.069  4.039   -28.926 1.00 53.38  ? 72  ASP H N   1 
ATOM   557  C CA  . ASP A 1 73  ? 13.159  3.728   -27.501 1.00 58.97  ? 72  ASP H CA  1 
ATOM   558  C C   . ASP A 1 73  ? 12.451  4.856   -26.758 1.00 63.58  ? 72  ASP H C   1 
ATOM   559  O O   . ASP A 1 73  ? 13.024  5.932   -26.561 1.00 68.15  ? 72  ASP H O   1 
ATOM   560  C CB  . ASP A 1 73  ? 14.611  3.582   -27.054 1.00 64.06  ? 72  ASP H CB  1 
ATOM   561  C CG  . ASP A 1 73  ? 14.738  3.040   -25.641 1.00 72.22  ? 72  ASP H CG  1 
ATOM   562  O OD1 . ASP A 1 73  ? 13.697  2.767   -25.006 1.00 75.67  ? 72  ASP H OD1 1 
ATOM   563  O OD2 . ASP A 1 73  ? 15.884  2.885   -25.166 1.00 64.14  ? 72  ASP H OD2 1 
ATOM   564  N N   . LYS A 1 74  ? 11.204  4.610   -26.349 1.00 54.19  ? 73  LYS H N   1 
ATOM   565  C CA  . LYS A 1 74  ? 10.400  5.651   -25.721 1.00 49.60  ? 73  LYS H CA  1 
ATOM   566  C C   . LYS A 1 74  ? 10.904  6.041   -24.338 1.00 56.12  ? 73  LYS H C   1 
ATOM   567  O O   . LYS A 1 74  ? 10.458  7.062   -23.804 1.00 55.58  ? 73  LYS H O   1 
ATOM   568  C CB  . LYS A 1 74  ? 8.937   5.208   -25.637 1.00 41.28  ? 73  LYS H CB  1 
ATOM   569  C CG  . LYS A 1 74  ? 8.699   3.922   -24.862 1.00 51.23  ? 73  LYS H CG  1 
ATOM   570  C CD  . LYS A 1 74  ? 7.208   3.631   -24.747 1.00 40.19  ? 73  LYS H CD  1 
ATOM   571  C CE  . LYS A 1 74  ? 6.937   2.367   -23.948 1.00 46.36  ? 73  LYS H CE  1 
ATOM   572  N NZ  . LYS A 1 74  ? 5.476   2.140   -23.759 1.00 52.78  ? 73  LYS H NZ  1 
ATOM   573  N N   . SER A 1 75  ? 11.813  5.261   -23.746 1.00 50.33  ? 74  SER H N   1 
ATOM   574  C CA  . SER A 1 75  ? 12.369  5.630   -22.448 1.00 45.57  ? 74  SER H CA  1 
ATOM   575  C C   . SER A 1 75  ? 13.174  6.921   -22.538 1.00 60.45  ? 74  SER H C   1 
ATOM   576  O O   . SER A 1 75  ? 13.103  7.770   -21.642 1.00 54.19  ? 74  SER H O   1 
ATOM   577  C CB  . SER A 1 75  ? 13.239  4.494   -21.908 1.00 51.47  ? 74  SER H CB  1 
ATOM   578  O OG  . SER A 1 75  ? 14.389  4.307   -22.713 1.00 54.48  ? 74  SER H OG  1 
ATOM   579  N N   . ILE A 1 76  ? 13.945  7.086   -23.611 1.00 55.75  ? 75  ILE H N   1 
ATOM   580  C CA  . ILE A 1 76  ? 14.821  8.238   -23.785 1.00 51.46  ? 75  ILE H CA  1 
ATOM   581  C C   . ILE A 1 76  ? 14.382  9.118   -24.946 1.00 54.61  ? 75  ILE H C   1 
ATOM   582  O O   . ILE A 1 76  ? 15.147  9.987   -25.378 1.00 59.78  ? 75  ILE H O   1 
ATOM   583  C CB  . ILE A 1 76  ? 16.285  7.801   -23.956 1.00 57.38  ? 75  ILE H CB  1 
ATOM   584  C CG1 . ILE A 1 76  ? 16.381  6.655   -24.965 1.00 57.76  ? 75  ILE H CG1 1 
ATOM   585  C CG2 . ILE A 1 76  ? 16.885  7.408   -22.614 1.00 66.17  ? 75  ILE H CG2 1 
ATOM   586  C CD1 . ILE A 1 76  ? 17.799  6.251   -25.300 1.00 47.32  ? 75  ILE H CD1 1 
ATOM   587  N N   . ASN A 1 77  ? 13.169  8.915   -25.465 1.00 51.96  ? 76  ASN H N   1 
ATOM   588  C CA  . ASN A 1 77  ? 12.606  9.754   -26.528 1.00 56.59  ? 76  ASN H CA  1 
ATOM   589  C C   . ASN A 1 77  ? 13.525  9.815   -27.747 1.00 55.98  ? 76  ASN H C   1 
ATOM   590  O O   . ASN A 1 77  ? 13.748  10.881  -28.325 1.00 51.62  ? 76  ASN H O   1 
ATOM   591  C CB  . ASN A 1 77  ? 12.297  11.162  -26.013 1.00 48.68  ? 76  ASN H CB  1 
ATOM   592  C CG  . ASN A 1 77  ? 11.316  11.158  -24.856 1.00 47.74  ? 76  ASN H CG  1 
ATOM   593  O OD1 . ASN A 1 77  ? 10.555  10.207  -24.676 1.00 60.90  ? 76  ASN H OD1 1 
ATOM   594  N ND2 . ASN A 1 77  ? 11.322  12.229  -24.070 1.00 57.84  ? 76  ASN H ND2 1 
ATOM   595  N N   . THR A 1 78  ? 14.064  8.664   -28.145 1.00 53.53  ? 77  THR H N   1 
ATOM   596  C CA  . THR A 1 78  ? 15.019  8.592   -29.244 1.00 56.71  ? 77  THR H CA  1 
ATOM   597  C C   . THR A 1 78  ? 14.553  7.566   -30.267 1.00 56.01  ? 77  THR H C   1 
ATOM   598  O O   . THR A 1 78  ? 14.179  6.446   -29.903 1.00 52.64  ? 77  THR H O   1 
ATOM   599  C CB  . THR A 1 78  ? 16.418  8.231   -28.732 1.00 51.96  ? 77  THR H CB  1 
ATOM   600  O OG1 . THR A 1 78  ? 16.764  9.094   -27.641 1.00 49.63  ? 77  THR H OG1 1 
ATOM   601  C CG2 . THR A 1 78  ? 17.450  8.392   -29.838 1.00 55.45  ? 77  THR H CG2 1 
ATOM   602  N N   . ALA A 1 79  ? 14.579  7.952   -31.539 1.00 53.50  ? 78  ALA H N   1 
ATOM   603  C CA  . ALA A 1 79  ? 14.262  7.073   -32.654 1.00 36.61  ? 78  ALA H CA  1 
ATOM   604  C C   . ALA A 1 79  ? 15.534  6.754   -33.428 1.00 45.23  ? 78  ALA H C   1 
ATOM   605  O O   . ALA A 1 79  ? 16.522  7.489   -33.369 1.00 58.20  ? 78  ALA H O   1 
ATOM   606  C CB  . ALA A 1 79  ? 13.222  7.710   -33.582 1.00 23.72  ? 78  ALA H CB  1 
ATOM   607  N N   . TYR A 1 80  ? 15.503  5.643   -34.161 1.00 44.49  ? 79  TYR H N   1 
ATOM   608  C CA  . TYR A 1 80  ? 16.695  5.136   -34.823 1.00 43.76  ? 79  TYR H CA  1 
ATOM   609  C C   . TYR A 1 80  ? 16.396  4.734   -36.260 1.00 44.89  ? 79  TYR H C   1 
ATOM   610  O O   . TYR A 1 80  ? 15.270  4.365   -36.605 1.00 47.88  ? 79  TYR H O   1 
ATOM   611  C CB  . TYR A 1 80  ? 17.279  3.936   -34.064 1.00 45.52  ? 79  TYR H CB  1 
ATOM   612  C CG  . TYR A 1 80  ? 17.681  4.259   -32.645 1.00 42.36  ? 79  TYR H CG  1 
ATOM   613  C CD1 . TYR A 1 80  ? 18.959  4.717   -32.353 1.00 52.32  ? 79  TYR H CD1 1 
ATOM   614  C CD2 . TYR A 1 80  ? 16.782  4.112   -31.597 1.00 40.25  ? 79  TYR H CD2 1 
ATOM   615  C CE1 . TYR A 1 80  ? 19.332  5.018   -31.058 1.00 57.62  ? 79  TYR H CE1 1 
ATOM   616  C CE2 . TYR A 1 80  ? 17.145  4.410   -30.298 1.00 51.10  ? 79  TYR H CE2 1 
ATOM   617  C CZ  . TYR A 1 80  ? 18.421  4.862   -30.034 1.00 54.62  ? 79  TYR H CZ  1 
ATOM   618  O OH  . TYR A 1 80  ? 18.788  5.160   -28.741 1.00 63.26  ? 79  TYR H OH  1 
ATOM   619  N N   . LEU A 1 81  ? 17.432  4.817   -37.093 1.00 46.04  ? 80  LEU H N   1 
ATOM   620  C CA  . LEU A 1 81  ? 17.413  4.306   -38.459 1.00 37.34  ? 80  LEU H CA  1 
ATOM   621  C C   . LEU A 1 81  ? 18.726  3.574   -38.680 1.00 40.42  ? 80  LEU H C   1 
ATOM   622  O O   . LEU A 1 81  ? 19.797  4.175   -38.554 1.00 42.17  ? 80  LEU H O   1 
ATOM   623  C CB  . LEU A 1 81  ? 17.240  5.435   -39.478 1.00 46.66  ? 80  LEU H CB  1 
ATOM   624  C CG  . LEU A 1 81  ? 17.290  5.033   -40.953 1.00 44.39  ? 80  LEU H CG  1 
ATOM   625  C CD1 . LEU A 1 81  ? 16.137  4.107   -41.294 1.00 41.94  ? 80  LEU H CD1 1 
ATOM   626  C CD2 . LEU A 1 81  ? 17.272  6.266   -41.840 1.00 37.29  ? 80  LEU H CD2 1 
ATOM   627  N N   . GLN A 1 82  ? 18.649  2.286   -39.005 1.00 42.37  ? 81  GLN H N   1 
ATOM   628  C CA  . GLN A 1 82  ? 19.813  1.415   -38.972 1.00 41.08  ? 81  GLN H CA  1 
ATOM   629  C C   . GLN A 1 82  ? 19.931  0.619   -40.265 1.00 41.15  ? 81  GLN H C   1 
ATOM   630  O O   . GLN A 1 82  ? 18.929  0.250   -40.883 1.00 44.73  ? 81  GLN H O   1 
ATOM   631  C CB  . GLN A 1 82  ? 19.735  0.463   -37.772 1.00 38.10  ? 81  GLN H CB  1 
ATOM   632  C CG  . GLN A 1 82  ? 18.468  -0.379  -37.762 1.00 66.68  ? 81  GLN H CG  1 
ATOM   633  C CD  . GLN A 1 82  ? 17.909  -0.625  -36.369 1.00 71.36  ? 81  GLN H CD  1 
ATOM   634  O OE1 . GLN A 1 82  ? 18.253  -1.612  -35.715 1.00 61.19  ? 81  GLN H OE1 1 
ATOM   635  N NE2 . GLN A 1 82  ? 17.031  0.267   -35.915 1.00 54.17  ? 81  GLN H NE2 1 
ATOM   636  N N   . TRP A 1 83  ? 21.177  0.361   -40.664 1.00 39.26  ? 82  TRP H N   1 
ATOM   637  C CA  . TRP A 1 83  ? 21.499  -0.499  -41.793 1.00 37.77  ? 82  TRP H CA  1 
ATOM   638  C C   . TRP A 1 83  ? 22.356  -1.659  -41.311 1.00 46.85  ? 82  TRP H C   1 
ATOM   639  O O   . TRP A 1 83  ? 23.188  -1.496  -40.412 1.00 49.95  ? 82  TRP H O   1 
ATOM   640  C CB  . TRP A 1 83  ? 22.256  0.256   -42.892 1.00 45.13  ? 82  TRP H CB  1 
ATOM   641  C CG  . TRP A 1 83  ? 21.507  1.383   -43.522 1.00 43.19  ? 82  TRP H CG  1 
ATOM   642  C CD1 . TRP A 1 83  ? 20.781  1.342   -44.675 1.00 38.80  ? 82  TRP H CD1 1 
ATOM   643  C CD2 . TRP A 1 83  ? 21.433  2.731   -43.047 1.00 41.21  ? 82  TRP H CD2 1 
ATOM   644  N NE1 . TRP A 1 83  ? 20.252  2.581   -44.944 1.00 47.32  ? 82  TRP H NE1 1 
ATOM   645  C CE2 . TRP A 1 83  ? 20.634  3.451   -43.958 1.00 38.52  ? 82  TRP H CE2 1 
ATOM   646  C CE3 . TRP A 1 83  ? 21.959  3.399   -41.937 1.00 46.30  ? 82  TRP H CE3 1 
ATOM   647  C CZ2 . TRP A 1 83  ? 20.348  4.804   -43.793 1.00 34.69  ? 82  TRP H CZ2 1 
ATOM   648  C CZ3 . TRP A 1 83  ? 21.674  4.742   -41.775 1.00 53.68  ? 82  TRP H CZ3 1 
ATOM   649  C CH2 . TRP A 1 83  ? 20.876  5.430   -42.698 1.00 46.70  ? 82  TRP H CH2 1 
ATOM   650  N N   . SER A 1 84  A 22.155  -2.831  -41.914 1.00 50.73  ? 82  SER H N   1 
ATOM   651  C CA  . SER A 1 84  A 23.006  -3.972  -41.596 1.00 50.79  ? 82  SER H CA  1 
ATOM   652  C C   . SER A 1 84  A 24.309  -3.917  -42.384 1.00 47.31  ? 82  SER H C   1 
ATOM   653  O O   . SER A 1 84  A 25.398  -3.977  -41.803 1.00 51.59  ? 82  SER H O   1 
ATOM   654  C CB  . SER A 1 84  A 22.262  -5.280  -41.870 1.00 47.90  ? 82  SER H CB  1 
ATOM   655  O OG  . SER A 1 84  A 21.880  -5.378  -43.230 1.00 69.44  ? 82  SER H OG  1 
ATOM   656  N N   . SER A 1 85  B 24.216  -3.795  -43.707 1.00 49.20  ? 82  SER H N   1 
ATOM   657  C CA  . SER A 1 85  B 25.384  -3.645  -44.569 1.00 51.88  ? 82  SER H CA  1 
ATOM   658  C C   . SER A 1 85  B 25.169  -2.438  -45.467 1.00 55.05  ? 82  SER H C   1 
ATOM   659  O O   . SER A 1 85  B 24.258  -2.437  -46.303 1.00 61.17  ? 82  SER H O   1 
ATOM   660  C CB  . SER A 1 85  B 25.624  -4.902  -45.410 1.00 42.86  ? 82  SER H CB  1 
ATOM   661  O OG  . SER A 1 85  B 24.694  -4.983  -46.477 1.00 64.47  ? 82  SER H OG  1 
ATOM   662  N N   . LEU A 1 86  C 26.003  -1.418  -45.296 1.00 44.70  ? 82  LEU H N   1 
ATOM   663  C CA  . LEU A 1 86  C 25.868  -0.201  -46.081 1.00 52.44  ? 82  LEU H CA  1 
ATOM   664  C C   . LEU A 1 86  C 26.324  -0.419  -47.519 1.00 53.84  ? 82  LEU H C   1 
ATOM   665  O O   . LEU A 1 86  C 27.257  -1.178  -47.795 1.00 55.86  ? 82  LEU H O   1 
ATOM   666  C CB  . LEU A 1 86  C 26.673  0.934   -45.451 1.00 47.14  ? 82  LEU H CB  1 
ATOM   667  C CG  . LEU A 1 86  C 26.071  1.575   -44.202 1.00 38.55  ? 82  LEU H CG  1 
ATOM   668  C CD1 . LEU A 1 86  C 27.053  2.545   -43.577 1.00 42.90  ? 82  LEU H CD1 1 
ATOM   669  C CD2 . LEU A 1 86  C 24.774  2.283   -44.548 1.00 38.51  ? 82  LEU H CD2 1 
ATOM   670  N N   . LYS A 1 87  ? 25.646  0.259   -48.436 1.00 54.32  ? 83  LYS H N   1 
ATOM   671  C CA  . LYS A 1 87  ? 26.038  0.334   -49.833 1.00 54.19  ? 83  LYS H CA  1 
ATOM   672  C C   . LYS A 1 87  ? 26.451  1.763   -50.159 1.00 53.87  ? 83  LYS H C   1 
ATOM   673  O O   . LYS A 1 87  ? 26.080  2.712   -49.465 1.00 61.37  ? 83  LYS H O   1 
ATOM   674  C CB  . LYS A 1 87  ? 24.895  -0.105  -50.756 1.00 40.11  ? 83  LYS H CB  1 
ATOM   675  C CG  . LYS A 1 87  ? 24.390  -1.517  -50.509 1.00 37.06  ? 83  LYS H CG  1 
ATOM   676  C CD  . LYS A 1 87  ? 23.194  -1.826  -51.399 1.00 59.12  ? 83  LYS H CD  1 
ATOM   677  C CE  . LYS A 1 87  ? 22.685  -3.241  -51.180 1.00 63.37  ? 83  LYS H CE  1 
ATOM   678  N NZ  . LYS A 1 87  ? 22.257  -3.461  -49.772 1.00 54.49  ? 83  LYS H NZ  1 
ATOM   679  N N   . ALA A 1 88  ? 27.238  1.907   -51.228 1.00 51.84  ? 84  ALA H N   1 
ATOM   680  C CA  . ALA A 1 88  ? 27.631  3.241   -51.668 1.00 51.53  ? 84  ALA H CA  1 
ATOM   681  C C   . ALA A 1 88  ? 26.422  4.064   -52.089 1.00 54.14  ? 84  ALA H C   1 
ATOM   682  O O   . ALA A 1 88  ? 26.441  5.296   -51.984 1.00 52.64  ? 84  ALA H O   1 
ATOM   683  C CB  . ALA A 1 88  ? 28.635  3.142   -52.816 1.00 62.70  ? 84  ALA H CB  1 
ATOM   684  N N   . SER A 1 89  ? 25.359  3.403   -52.552 1.00 53.54  ? 85  SER H N   1 
ATOM   685  C CA  . SER A 1 89  ? 24.132  4.088   -52.935 1.00 47.32  ? 85  SER H CA  1 
ATOM   686  C C   . SER A 1 89  ? 23.375  4.653   -51.739 1.00 53.35  ? 85  SER H C   1 
ATOM   687  O O   . SER A 1 89  ? 22.408  5.396   -51.937 1.00 52.29  ? 85  SER H O   1 
ATOM   688  C CB  . SER A 1 89  ? 23.231  3.137   -53.725 1.00 51.16  ? 85  SER H CB  1 
ATOM   689  O OG  . SER A 1 89  ? 23.199  1.852   -53.129 1.00 69.55  ? 85  SER H OG  1 
ATOM   690  N N   . ASP A 1 90  ? 23.781  4.316   -50.516 1.00 50.53  ? 86  ASP H N   1 
ATOM   691  C CA  . ASP A 1 90  ? 23.179  4.885   -49.319 1.00 48.30  ? 86  ASP H CA  1 
ATOM   692  C C   . ASP A 1 90  ? 23.790  6.225   -48.928 1.00 47.13  ? 86  ASP H C   1 
ATOM   693  O O   . ASP A 1 90  ? 23.368  6.807   -47.924 1.00 49.67  ? 86  ASP H O   1 
ATOM   694  C CB  . ASP A 1 90  ? 23.303  3.907   -48.146 1.00 52.67  ? 86  ASP H CB  1 
ATOM   695  C CG  . ASP A 1 90  ? 22.521  2.629   -48.368 1.00 56.63  ? 86  ASP H CG  1 
ATOM   696  O OD1 . ASP A 1 90  ? 21.479  2.680   -49.055 1.00 54.37  ? 86  ASP H OD1 1 
ATOM   697  O OD2 . ASP A 1 90  ? 22.947  1.574   -47.852 1.00 54.96  ? 86  ASP H OD2 1 
ATOM   698  N N   . THR A 1 91  ? 24.767  6.721   -49.684 1.00 43.90  ? 87  THR H N   1 
ATOM   699  C CA  . THR A 1 91  ? 25.403  8.003   -49.388 1.00 50.64  ? 87  THR H CA  1 
ATOM   700  C C   . THR A 1 91  ? 24.394  9.117   -49.633 1.00 54.99  ? 87  THR H C   1 
ATOM   701  O O   . THR A 1 91  ? 24.130  9.494   -50.777 1.00 53.34  ? 87  THR H O   1 
ATOM   702  C CB  . THR A 1 91  ? 26.649  8.196   -50.246 1.00 43.54  ? 87  THR H CB  1 
ATOM   703  O OG1 . THR A 1 91  ? 27.600  7.165   -49.952 1.00 50.59  ? 87  THR H OG1 1 
ATOM   704  C CG2 . THR A 1 91  ? 27.280  9.556   -49.975 1.00 27.25  ? 87  THR H CG2 1 
ATOM   705  N N   . ALA A 1 92  ? 23.826  9.650   -48.554 1.00 50.44  ? 88  ALA H N   1 
ATOM   706  C CA  . ALA A 1 92  ? 22.800  10.676  -48.663 1.00 43.84  ? 88  ALA H CA  1 
ATOM   707  C C   . ALA A 1 92  ? 22.653  11.382  -47.325 1.00 43.53  ? 88  ALA H C   1 
ATOM   708  O O   . ALA A 1 92  ? 23.124  10.901  -46.291 1.00 45.49  ? 88  ALA H O   1 
ATOM   709  C CB  . ALA A 1 92  ? 21.457  10.083  -49.102 1.00 45.39  ? 88  ALA H CB  1 
ATOM   710  N N   . MET A 1 93  ? 21.993  12.536  -47.365 1.00 47.17  ? 89  MET H N   1 
ATOM   711  C CA  . MET A 1 93  ? 21.599  13.235  -46.151 1.00 36.84  ? 89  MET H CA  1 
ATOM   712  C C   . MET A 1 93  ? 20.276  12.669  -45.654 1.00 35.31  ? 89  MET H C   1 
ATOM   713  O O   . MET A 1 93  ? 19.326  12.518  -46.430 1.00 34.19  ? 89  MET H O   1 
ATOM   714  C CB  . MET A 1 93  ? 21.469  14.735  -46.415 1.00 37.09  ? 89  MET H CB  1 
ATOM   715  C CG  . MET A 1 93  ? 20.908  15.527  -45.244 1.00 46.25  ? 89  MET H CG  1 
ATOM   716  S SD  . MET A 1 93  ? 22.175  16.219  -44.165 1.00 42.17  ? 89  MET H SD  1 
ATOM   717  C CE  . MET A 1 93  ? 22.838  17.513  -45.212 1.00 30.60  ? 89  MET H CE  1 
ATOM   718  N N   . TYR A 1 94  ? 20.214  12.348  -44.366 1.00 38.65  ? 90  TYR H N   1 
ATOM   719  C CA  . TYR A 1 94  ? 19.030  11.749  -43.764 1.00 33.10  ? 90  TYR H CA  1 
ATOM   720  C C   . TYR A 1 94  ? 18.445  12.706  -42.736 1.00 33.05  ? 90  TYR H C   1 
ATOM   721  O O   . TYR A 1 94  ? 19.138  13.119  -41.799 1.00 44.00  ? 90  TYR H O   1 
ATOM   722  C CB  . TYR A 1 94  ? 19.367  10.403  -43.123 1.00 28.54  ? 90  TYR H CB  1 
ATOM   723  C CG  . TYR A 1 94  ? 19.720  9.332   -44.129 1.00 34.27  ? 90  TYR H CG  1 
ATOM   724  C CD1 . TYR A 1 94  ? 18.728  8.650   -44.819 1.00 36.07  ? 90  TYR H CD1 1 
ATOM   725  C CD2 . TYR A 1 94  ? 21.044  9.006   -44.392 1.00 48.89  ? 90  TYR H CD2 1 
ATOM   726  C CE1 . TYR A 1 94  ? 19.043  7.671   -45.739 1.00 42.38  ? 90  TYR H CE1 1 
ATOM   727  C CE2 . TYR A 1 94  ? 21.369  8.027   -45.313 1.00 42.55  ? 90  TYR H CE2 1 
ATOM   728  C CZ  . TYR A 1 94  ? 20.364  7.365   -45.985 1.00 37.58  ? 90  TYR H CZ  1 
ATOM   729  O OH  . TYR A 1 94  ? 20.679  6.389   -46.903 1.00 39.80  ? 90  TYR H OH  1 
ATOM   730  N N   . TYR A 1 95  ? 17.174  13.053  -42.914 1.00 29.37  ? 91  TYR H N   1 
ATOM   731  C CA  . TYR A 1 95  ? 16.435  13.890  -41.983 1.00 37.23  ? 91  TYR H CA  1 
ATOM   732  C C   . TYR A 1 95  ? 15.406  13.049  -41.240 1.00 32.25  ? 91  TYR H C   1 
ATOM   733  O O   . TYR A 1 95  ? 14.869  12.077  -41.778 1.00 30.12  ? 91  TYR H O   1 
ATOM   734  C CB  . TYR A 1 95  ? 15.713  15.035  -42.705 1.00 35.05  ? 91  TYR H CB  1 
ATOM   735  C CG  . TYR A 1 95  ? 16.605  16.026  -43.422 1.00 31.79  ? 91  TYR H CG  1 
ATOM   736  C CD1 . TYR A 1 95  ? 17.166  17.100  -42.745 1.00 35.73  ? 91  TYR H CD1 1 
ATOM   737  C CD2 . TYR A 1 95  ? 16.857  15.906  -44.782 1.00 32.92  ? 91  TYR H CD2 1 
ATOM   738  C CE1 . TYR A 1 95  ? 17.973  18.014  -43.397 1.00 45.55  ? 91  TYR H CE1 1 
ATOM   739  C CE2 . TYR A 1 95  ? 17.659  16.817  -45.444 1.00 39.42  ? 91  TYR H CE2 1 
ATOM   740  C CZ  . TYR A 1 95  ? 18.215  17.869  -44.746 1.00 45.62  ? 91  TYR H CZ  1 
ATOM   741  O OH  . TYR A 1 95  ? 19.016  18.778  -45.399 1.00 44.58  ? 91  TYR H OH  1 
ATOM   742  N N   . CYS A 1 96  ? 15.131  13.430  -39.996 1.00 36.35  ? 92  CYS H N   1 
ATOM   743  C CA  . CYS A 1 96  ? 13.999  12.897  -39.253 1.00 35.92  ? 92  CYS H CA  1 
ATOM   744  C C   . CYS A 1 96  ? 12.990  14.015  -39.044 1.00 34.09  ? 92  CYS H C   1 
ATOM   745  O O   . CYS A 1 96  ? 13.364  15.137  -38.684 1.00 34.55  ? 92  CYS H O   1 
ATOM   746  C CB  . CYS A 1 96  ? 14.425  12.292  -37.910 1.00 38.34  ? 92  CYS H CB  1 
ATOM   747  S SG  . CYS A 1 96  ? 15.215  13.409  -36.724 1.00 64.40  ? 92  CYS H SG  1 
ATOM   748  N N   . ALA A 1 97  ? 11.719  13.713  -39.287 1.00 39.66  ? 93  ALA H N   1 
ATOM   749  C CA  . ALA A 1 97  ? 10.656  14.701  -39.211 1.00 41.76  ? 93  ALA H CA  1 
ATOM   750  C C   . ALA A 1 97  ? 9.553   14.204  -38.290 1.00 44.46  ? 93  ALA H C   1 
ATOM   751  O O   . ALA A 1 97  ? 9.304   13.000  -38.182 1.00 37.80  ? 93  ALA H O   1 
ATOM   752  C CB  . ALA A 1 97  ? 10.080  15.017  -40.596 1.00 43.55  ? 93  ALA H CB  1 
ATOM   753  N N   . GLY A 1 98  ? 8.892   15.145  -37.632 1.00 47.28  ? 94  GLY H N   1 
ATOM   754  C CA  . GLY A 1 98  ? 7.841   14.833  -36.674 1.00 40.07  ? 94  GLY H CA  1 
ATOM   755  C C   . GLY A 1 98  ? 6.514   15.441  -37.078 1.00 42.31  ? 94  GLY H C   1 
ATOM   756  O O   . GLY A 1 98  ? 6.467   16.549  -37.614 1.00 36.42  ? 94  GLY H O   1 
ATOM   757  N N   . GLY A 1 99  ? 5.444   14.704  -36.819 1.00 49.00  ? 95  GLY H N   1 
ATOM   758  C CA  . GLY A 1 99  ? 4.099   15.205  -37.042 1.00 39.73  ? 95  GLY H CA  1 
ATOM   759  C C   . GLY A 1 99  ? 3.171   14.653  -35.985 1.00 46.75  ? 95  GLY H C   1 
ATOM   760  O O   . GLY A 1 99  ? 3.370   13.549  -35.471 1.00 49.17  ? 95  GLY H O   1 
ATOM   761  N N   . SER A 1 100 ? 2.136   15.427  -35.673 1.00 48.46  ? 96  SER H N   1 
ATOM   762  C CA  . SER A 1 100 ? 1.274   15.118  -34.537 1.00 51.71  ? 96  SER H CA  1 
ATOM   763  C C   . SER A 1 100 ? 0.214   14.067  -34.856 1.00 54.15  ? 96  SER H C   1 
ATOM   764  O O   . SER A 1 100 ? -0.803  13.992  -34.157 1.00 59.14  ? 96  SER H O   1 
ATOM   765  C CB  . SER A 1 100 ? 0.619   16.395  -34.005 1.00 46.36  ? 96  SER H CB  1 
ATOM   766  O OG  . SER A 1 100 ? -0.024  17.114  -35.038 1.00 52.38  ? 96  SER H OG  1 
ATOM   767  N N   . GLY A 1 101 ? 0.428   13.259  -35.885 1.00 51.04  ? 97  GLY H N   1 
ATOM   768  C CA  . GLY A 1 101 ? -0.442  12.127  -36.152 1.00 41.29  ? 97  GLY H CA  1 
ATOM   769  C C   . GLY A 1 101 ? 0.019   11.424  -37.407 1.00 42.33  ? 97  GLY H C   1 
ATOM   770  O O   . GLY A 1 101 ? 0.920   11.888  -38.113 1.00 50.73  ? 97  GLY H O   1 
ATOM   771  N N   . ILE A 1 102 ? -0.588  10.275  -37.657 1.00 41.55  ? 98  ILE H N   1 
ATOM   772  C CA  . ILE A 1 102 ? -0.449  9.653   -38.965 1.00 35.56  ? 98  ILE H CA  1 
ATOM   773  C C   . ILE A 1 102 ? -1.398  10.365  -39.917 1.00 35.81  ? 98  ILE H C   1 
ATOM   774  O O   . ILE A 1 102 ? -2.465  10.849  -39.514 1.00 43.37  ? 98  ILE H O   1 
ATOM   775  C CB  . ILE A 1 102 ? -0.710  8.135   -38.908 1.00 43.51  ? 98  ILE H CB  1 
ATOM   776  C CG1 . ILE A 1 102 ? -0.139  7.464   -40.154 1.00 38.88  ? 98  ILE H CG1 1 
ATOM   777  C CG2 . ILE A 1 102 ? -2.177  7.835   -38.774 1.00 48.13  ? 98  ILE H CG2 1 
ATOM   778  C CD1 . ILE A 1 102 ? 1.376   7.323   -40.105 1.00 48.13  ? 98  ILE H CD1 1 
ATOM   779  N N   . PHE A 1 103 ? -0.983  10.486  -41.177 1.00 36.64  ? 99  PHE H N   1 
ATOM   780  C CA  . PHE A 1 103 ? -1.700  11.285  -42.173 1.00 37.41  ? 99  PHE H CA  1 
ATOM   781  C C   . PHE A 1 103 ? -1.817  12.734  -41.713 1.00 36.57  ? 99  PHE H C   1 
ATOM   782  O O   . PHE A 1 103 ? -2.898  13.333  -41.707 1.00 37.67  ? 99  PHE H O   1 
ATOM   783  C CB  . PHE A 1 103 ? -3.076  10.702  -42.483 1.00 28.39  ? 99  PHE H CB  1 
ATOM   784  C CG  . PHE A 1 103 ? -3.058  9.223   -42.678 1.00 32.43  ? 99  PHE H CG  1 
ATOM   785  C CD1 . PHE A 1 103 ? -2.317  8.663   -43.702 1.00 34.00  ? 99  PHE H CD1 1 
ATOM   786  C CD2 . PHE A 1 103 ? -3.771  8.390   -41.835 1.00 40.68  ? 99  PHE H CD2 1 
ATOM   787  C CE1 . PHE A 1 103 ? -2.284  7.302   -43.883 1.00 37.22  ? 99  PHE H CE1 1 
ATOM   788  C CE2 . PHE A 1 103 ? -3.746  7.025   -42.010 1.00 34.87  ? 99  PHE H CE2 1 
ATOM   789  C CZ  . PHE A 1 103 ? -3.001  6.479   -43.037 1.00 43.59  ? 99  PHE H CZ  1 
ATOM   790  N N   . THR A 1 104 ? -0.681  13.283  -41.292 1.00 37.62  ? 100 THR H N   1 
ATOM   791  C CA  . THR A 1 104 ? -0.535  14.664  -40.871 1.00 34.16  ? 100 THR H CA  1 
ATOM   792  C C   . THR A 1 104 ? 0.780   15.179  -41.428 1.00 40.51  ? 100 THR H C   1 
ATOM   793  O O   . THR A 1 104 ? 1.758   14.419  -41.492 1.00 41.92  ? 100 THR H O   1 
ATOM   794  C CB  . THR A 1 104 ? -0.506  14.828  -39.347 1.00 38.02  ? 100 THR H CB  1 
ATOM   795  O OG1 . THR A 1 104 ? 0.589   14.078  -38.805 1.00 50.77  ? 100 THR H OG1 1 
ATOM   796  C CG2 . THR A 1 104 ? -1.804  14.369  -38.741 1.00 44.77  ? 100 THR H CG2 1 
ATOM   797  N N   . PRO A 1 105 A 0.854   16.459  -41.783 1.00 32.37  ? 100 PRO H N   1 
ATOM   798  C CA  . PRO A 1 105 A 2.110   17.006  -42.314 1.00 37.44  ? 100 PRO H CA  1 
ATOM   799  C C   . PRO A 1 105 A 3.214   17.024  -41.266 1.00 35.94  ? 100 PRO H C   1 
ATOM   800  O O   . PRO A 1 105 A 2.965   17.149  -40.065 1.00 43.18  ? 100 PRO H O   1 
ATOM   801  C CB  . PRO A 1 105 A 1.723   18.426  -42.740 1.00 35.57  ? 100 PRO H CB  1 
ATOM   802  C CG  . PRO A 1 105 A 0.550   18.758  -41.868 1.00 44.28  ? 100 PRO H CG  1 
ATOM   803  C CD  . PRO A 1 105 A -0.192  17.487  -41.638 1.00 40.85  ? 100 PRO H CD  1 
ATOM   804  N N   . MET A 1 106 B 4.448   16.882  -41.738 1.00 45.34  ? 100 MET H N   1 
ATOM   805  C CA  . MET A 1 106 B 5.608   16.832  -40.856 1.00 40.80  ? 100 MET H CA  1 
ATOM   806  C C   . MET A 1 106 B 5.941   18.250  -40.406 1.00 38.19  ? 100 MET H C   1 
ATOM   807  O O   . MET A 1 106 B 6.380   19.078  -41.211 1.00 30.67  ? 100 MET H O   1 
ATOM   808  C CB  . MET A 1 106 B 6.783   16.175  -41.575 1.00 41.80  ? 100 MET H CB  1 
ATOM   809  C CG  . MET A 1 106 B 6.354   15.162  -42.638 1.00 43.38  ? 100 MET H CG  1 
ATOM   810  S SD  . MET A 1 106 B 7.520   13.808  -42.890 1.00 63.93  ? 100 MET H SD  1 
ATOM   811  C CE  . MET A 1 106 B 7.174   12.794  -41.454 1.00 45.85  ? 100 MET H CE  1 
ATOM   812  N N   . ASP A 1 107 ? 5.734   18.531  -39.119 1.00 41.67  ? 101 ASP H N   1 
ATOM   813  C CA  . ASP A 1 107 ? 5.890   19.872  -38.568 1.00 33.57  ? 101 ASP H CA  1 
ATOM   814  C C   . ASP A 1 107 ? 7.321   20.170  -38.146 1.00 36.79  ? 101 ASP H C   1 
ATOM   815  O O   . ASP A 1 107 ? 7.866   21.226  -38.483 1.00 49.21  ? 101 ASP H O   1 
ATOM   816  C CB  . ASP A 1 107 ? 4.958   20.052  -37.371 1.00 40.14  ? 101 ASP H CB  1 
ATOM   817  C CG  . ASP A 1 107 ? 3.512   19.947  -37.755 1.00 47.94  ? 101 ASP H CG  1 
ATOM   818  O OD1 . ASP A 1 107 ? 2.781   19.159  -37.122 1.00 55.15  ? 101 ASP H OD1 1 
ATOM   819  O OD2 . ASP A 1 107 ? 3.119   20.635  -38.716 1.00 62.47  ? 101 ASP H OD2 1 
ATOM   820  N N   . VAL A 1 108 ? 7.931   19.260  -37.396 1.00 37.76  ? 102 VAL H N   1 
ATOM   821  C CA  . VAL A 1 108 ? 9.248   19.464  -36.813 1.00 37.09  ? 102 VAL H CA  1 
ATOM   822  C C   . VAL A 1 108 ? 10.250  18.636  -37.600 1.00 46.94  ? 102 VAL H C   1 
ATOM   823  O O   . VAL A 1 108 ? 10.018  17.448  -37.856 1.00 52.67  ? 102 VAL H O   1 
ATOM   824  C CB  . VAL A 1 108 ? 9.272   19.081  -35.324 1.00 35.62  ? 102 VAL H CB  1 
ATOM   825  C CG1 . VAL A 1 108 ? 10.475  19.707  -34.645 1.00 46.57  ? 102 VAL H CG1 1 
ATOM   826  C CG2 . VAL A 1 108 ? 7.978   19.498  -34.645 1.00 41.54  ? 102 VAL H CG2 1 
ATOM   827  N N   . TRP A 1 109 ? 11.359  19.260  -37.981 1.00 37.90  ? 103 TRP H N   1 
ATOM   828  C CA  . TRP A 1 109 ? 12.426  18.592  -38.707 1.00 34.89  ? 103 TRP H CA  1 
ATOM   829  C C   . TRP A 1 109 ? 13.726  18.679  -37.920 1.00 35.28  ? 103 TRP H C   1 
ATOM   830  O O   . TRP A 1 109 ? 13.964  19.642  -37.184 1.00 52.63  ? 103 TRP H O   1 
ATOM   831  C CB  . TRP A 1 109 ? 12.625  19.207  -40.099 1.00 36.02  ? 103 TRP H CB  1 
ATOM   832  C CG  . TRP A 1 109 ? 11.496  18.944  -41.047 1.00 39.04  ? 103 TRP H CG  1 
ATOM   833  C CD1 . TRP A 1 109 ? 10.289  19.580  -41.081 1.00 41.64  ? 103 TRP H CD1 1 
ATOM   834  C CD2 . TRP A 1 109 ? 11.471  17.979  -42.108 1.00 41.43  ? 103 TRP H CD2 1 
ATOM   835  N NE1 . TRP A 1 109 ? 9.513   19.068  -42.093 1.00 46.36  ? 103 TRP H NE1 1 
ATOM   836  C CE2 . TRP A 1 109 ? 10.215  18.084  -42.738 1.00 38.56  ? 103 TRP H CE2 1 
ATOM   837  C CE3 . TRP A 1 109 ? 12.387  17.036  -42.583 1.00 46.65  ? 103 TRP H CE3 1 
ATOM   838  C CZ2 . TRP A 1 109 ? 9.853   17.282  -43.818 1.00 40.41  ? 103 TRP H CZ2 1 
ATOM   839  C CZ3 . TRP A 1 109 ? 12.025  16.240  -43.655 1.00 40.25  ? 103 TRP H CZ3 1 
ATOM   840  C CH2 . TRP A 1 109 ? 10.770  16.368  -44.260 1.00 45.62  ? 103 TRP H CH2 1 
ATOM   841  N N   . GLY A 1 110 ? 14.564  17.657  -38.075 1.00 36.02  ? 104 GLY H N   1 
ATOM   842  C CA  . GLY A 1 110 ? 15.902  17.687  -37.532 1.00 35.46  ? 104 GLY H CA  1 
ATOM   843  C C   . GLY A 1 110 ? 16.850  18.457  -38.429 1.00 36.36  ? 104 GLY H C   1 
ATOM   844  O O   . GLY A 1 110 ? 16.493  18.934  -39.506 1.00 48.58  ? 104 GLY H O   1 
ATOM   845  N N   . GLN A 1 111 ? 18.094  18.581  -37.967 1.00 35.63  ? 105 GLN H N   1 
ATOM   846  C CA  . GLN A 1 111 ? 19.096  19.306  -38.737 1.00 34.33  ? 105 GLN H CA  1 
ATOM   847  C C   . GLN A 1 111 ? 19.700  18.471  -39.857 1.00 45.46  ? 105 GLN H C   1 
ATOM   848  O O   . GLN A 1 111 ? 20.376  19.030  -40.728 1.00 50.57  ? 105 GLN H O   1 
ATOM   849  C CB  . GLN A 1 111 ? 20.213  19.818  -37.820 1.00 31.39  ? 105 GLN H CB  1 
ATOM   850  C CG  . GLN A 1 111 ? 21.225  18.765  -37.392 1.00 31.06  ? 105 GLN H CG  1 
ATOM   851  C CD  . GLN A 1 111 ? 20.770  17.959  -36.192 1.00 41.19  ? 105 GLN H CD  1 
ATOM   852  O OE1 . GLN A 1 111 ? 19.601  17.994  -35.809 1.00 41.22  ? 105 GLN H OE1 1 
ATOM   853  N NE2 . GLN A 1 111 ? 21.700  17.230  -35.585 1.00 40.67  ? 105 GLN H NE2 1 
ATOM   854  N N   . GLY A 1 112 ? 19.473  17.168  -39.861 1.00 38.48  ? 106 GLY H N   1 
ATOM   855  C CA  . GLY A 1 112 ? 20.010  16.305  -40.893 1.00 40.62  ? 106 GLY H CA  1 
ATOM   856  C C   . GLY A 1 112 ? 21.297  15.629  -40.461 1.00 45.39  ? 106 GLY H C   1 
ATOM   857  O O   . GLY A 1 112 ? 22.061  16.144  -39.637 1.00 55.06  ? 106 GLY H O   1 
ATOM   858  N N   . THR A 1 113 ? 21.542  14.448  -41.024 1.00 42.99  ? 107 THR H N   1 
ATOM   859  C CA  . THR A 1 113 ? 22.753  13.679  -40.755 1.00 43.63  ? 107 THR H CA  1 
ATOM   860  C C   . THR A 1 113 ? 23.351  13.247  -42.087 1.00 54.94  ? 107 THR H C   1 
ATOM   861  O O   . THR A 1 113 ? 22.750  12.445  -42.810 1.00 51.86  ? 107 THR H O   1 
ATOM   862  C CB  . THR A 1 113 ? 22.460  12.464  -39.874 1.00 43.42  ? 107 THR H CB  1 
ATOM   863  O OG1 . THR A 1 113 ? 22.004  12.901  -38.587 1.00 40.06  ? 107 THR H OG1 1 
ATOM   864  C CG2 . THR A 1 113 ? 23.713  11.618  -39.702 1.00 40.28  ? 107 THR H CG2 1 
ATOM   865  N N   . ALA A 1 114 ? 24.524  13.782  -42.413 1.00 53.77  ? 108 ALA H N   1 
ATOM   866  C CA  . ALA A 1 114 ? 25.223  13.393  -43.629 1.00 48.71  ? 108 ALA H CA  1 
ATOM   867  C C   . ALA A 1 114 ? 25.863  12.024  -43.438 1.00 50.52  ? 108 ALA H C   1 
ATOM   868  O O   . ALA A 1 114 ? 26.539  11.779  -42.434 1.00 47.03  ? 108 ALA H O   1 
ATOM   869  C CB  . ALA A 1 114 ? 26.281  14.432  -43.994 1.00 35.52  ? 108 ALA H CB  1 
ATOM   870  N N   . VAL A 1 115 ? 25.644  11.130  -44.399 1.00 52.70  ? 109 VAL H N   1 
ATOM   871  C CA  . VAL A 1 115 ? 26.198  9.783   -44.363 1.00 42.16  ? 109 VAL H CA  1 
ATOM   872  C C   . VAL A 1 115 ? 26.945  9.546   -45.667 1.00 44.83  ? 109 VAL H C   1 
ATOM   873  O O   . VAL A 1 115 ? 26.367  9.686   -46.751 1.00 46.96  ? 109 VAL H O   1 
ATOM   874  C CB  . VAL A 1 115 ? 25.111  8.715   -44.159 1.00 42.95  ? 109 VAL H CB  1 
ATOM   875  C CG1 . VAL A 1 115 ? 25.694  7.324   -44.341 1.00 42.07  ? 109 VAL H CG1 1 
ATOM   876  C CG2 . VAL A 1 115 ? 24.481  8.858   -42.780 1.00 36.96  ? 109 VAL H CG2 1 
ATOM   877  N N   . ALA A 1 116 ? 28.223  9.189   -45.563 1.00 43.46  ? 110 ALA H N   1 
ATOM   878  C CA  . ALA A 1 116 ? 29.060  8.905   -46.721 1.00 41.43  ? 110 ALA H CA  1 
ATOM   879  C C   . ALA A 1 116 ? 29.522  7.458   -46.651 1.00 40.05  ? 110 ALA H C   1 
ATOM   880  O O   . ALA A 1 116 ? 30.113  7.039   -45.650 1.00 41.47  ? 110 ALA H O   1 
ATOM   881  C CB  . ALA A 1 116 ? 30.262  9.851   -46.778 1.00 33.37  ? 110 ALA H CB  1 
ATOM   882  N N   . VAL A 1 117 ? 29.253  6.701   -47.710 1.00 39.79  ? 111 VAL H N   1 
ATOM   883  C CA  . VAL A 1 117 ? 29.676  5.309   -47.818 1.00 44.10  ? 111 VAL H CA  1 
ATOM   884  C C   . VAL A 1 117 ? 30.647  5.222   -48.984 1.00 44.48  ? 111 VAL H C   1 
ATOM   885  O O   . VAL A 1 117 ? 30.248  5.367   -50.147 1.00 56.24  ? 111 VAL H O   1 
ATOM   886  C CB  . VAL A 1 117 ? 28.492  4.355   -48.014 1.00 44.34  ? 111 VAL H CB  1 
ATOM   887  C CG1 . VAL A 1 117 ? 28.989  2.919   -48.074 1.00 45.00  ? 111 VAL H CG1 1 
ATOM   888  C CG2 . VAL A 1 117 ? 27.482  4.528   -46.891 1.00 38.80  ? 111 VAL H CG2 1 
ATOM   889  N N   . SER A 1 118 ? 31.919  4.985   -48.677 1.00 41.88  ? 112 SER H N   1 
ATOM   890  C CA  . SER A 1 118 ? 32.947  4.908   -49.700 1.00 51.31  ? 112 SER H CA  1 
ATOM   891  C C   . SER A 1 118 ? 34.011  3.915   -49.263 1.00 54.50  ? 112 SER H C   1 
ATOM   892  O O   . SER A 1 118 ? 34.258  3.736   -48.067 1.00 50.31  ? 112 SER H O   1 
ATOM   893  C CB  . SER A 1 118 ? 33.576  6.283   -49.962 1.00 35.49  ? 112 SER H CB  1 
ATOM   894  O OG  . SER A 1 118 ? 34.645  6.199   -50.886 1.00 43.63  ? 112 SER H OG  1 
ATOM   895  N N   . SER A 1 119 ? 34.642  3.277   -50.247 1.00 51.57  ? 113 SER H N   1 
ATOM   896  C CA  . SER A 1 119 ? 35.778  2.401   -50.004 1.00 56.47  ? 113 SER H CA  1 
ATOM   897  C C   . SER A 1 119 ? 37.075  3.179   -49.843 1.00 49.95  ? 113 SER H C   1 
ATOM   898  O O   . SER A 1 119 ? 38.147  2.567   -49.744 1.00 62.75  ? 113 SER H O   1 
ATOM   899  C CB  . SER A 1 119 ? 35.908  1.381   -51.143 1.00 72.05  ? 113 SER H CB  1 
ATOM   900  O OG  . SER A 1 119 ? 35.641  1.979   -52.398 1.00 73.87  ? 113 SER H OG  1 
ATOM   901  N N   . ALA A 1 120 ? 36.998  4.509   -49.796 1.00 45.74  ? 114 ALA H N   1 
ATOM   902  C CA  . ALA A 1 120 ? 38.174  5.362   -49.736 1.00 43.42  ? 114 ALA H CA  1 
ATOM   903  C C   . ALA A 1 120 ? 38.598  5.618   -48.296 1.00 48.32  ? 114 ALA H C   1 
ATOM   904  O O   . ALA A 1 120 ? 37.784  5.588   -47.369 1.00 47.91  ? 114 ALA H O   1 
ATOM   905  C CB  . ALA A 1 120 ? 37.911  6.700   -50.435 1.00 38.25  ? 114 ALA H CB  1 
ATOM   906  N N   . SER A 1 121 ? 39.889  5.882   -48.126 1.00 48.26  ? 115 SER H N   1 
ATOM   907  C CA  . SER A 1 121 ? 40.485  6.149   -46.828 1.00 49.49  ? 115 SER H CA  1 
ATOM   908  C C   . SER A 1 121 ? 40.741  7.642   -46.660 1.00 50.41  ? 115 SER H C   1 
ATOM   909  O O   . SER A 1 121 ? 40.780  8.403   -47.630 1.00 43.55  ? 115 SER H O   1 
ATOM   910  C CB  . SER A 1 121 ? 41.793  5.369   -46.667 1.00 43.82  ? 115 SER H CB  1 
ATOM   911  O OG  . SER A 1 121 ? 41.625  4.033   -47.100 1.00 36.28  ? 115 SER H OG  1 
ATOM   912  N N   . THR A 1 122 ? 40.918  8.054   -45.406 1.00 47.22  ? 116 THR H N   1 
ATOM   913  C CA  . THR A 1 122 ? 41.080  9.466   -45.088 1.00 41.98  ? 116 THR H CA  1 
ATOM   914  C C   . THR A 1 122 ? 42.409  9.982   -45.631 1.00 50.03  ? 116 THR H C   1 
ATOM   915  O O   . THR A 1 122 ? 43.477  9.500   -45.241 1.00 59.10  ? 116 THR H O   1 
ATOM   916  C CB  . THR A 1 122 ? 40.998  9.673   -43.581 1.00 48.36  ? 116 THR H CB  1 
ATOM   917  O OG1 . THR A 1 122 ? 39.740  9.181   -43.103 1.00 55.23  ? 116 THR H OG1 1 
ATOM   918  C CG2 . THR A 1 122 ? 41.121  11.144  -43.250 1.00 48.85  ? 116 THR H CG2 1 
ATOM   919  N N   . LYS A 1 123 ? 42.339  10.960  -46.534 1.00 44.52  ? 117 LYS H N   1 
ATOM   920  C CA  . LYS A 1 123 ? 43.514  11.513  -47.193 1.00 42.63  ? 117 LYS H CA  1 
ATOM   921  C C   . LYS A 1 123 ? 43.486  13.032  -47.100 1.00 43.54  ? 117 LYS H C   1 
ATOM   922  O O   . LYS A 1 123 ? 42.429  13.654  -47.245 1.00 44.24  ? 117 LYS H O   1 
ATOM   923  C CB  . LYS A 1 123 ? 43.577  11.070  -48.662 1.00 38.50  ? 117 LYS H CB  1 
ATOM   924  C CG  . LYS A 1 123 ? 44.979  11.017  -49.246 1.00 43.25  ? 117 LYS H CG  1 
ATOM   925  C CD  . LYS A 1 123 ? 45.272  12.216  -50.131 1.00 42.26  ? 117 LYS H CD  1 
ATOM   926  C CE  . LYS A 1 123 ? 46.662  12.118  -50.745 1.00 57.76  ? 117 LYS H CE  1 
ATOM   927  N NZ  . LYS A 1 123 ? 46.957  13.262  -51.653 1.00 65.17  ? 117 LYS H NZ  1 
ATOM   928  N N   . GLY A 1 124 ? 44.654  13.624  -46.859 1.00 54.75  ? 118 GLY H N   1 
ATOM   929  C CA  . GLY A 1 124 ? 44.769  15.055  -46.703 1.00 48.04  ? 118 GLY H CA  1 
ATOM   930  C C   . GLY A 1 124 ? 44.775  15.800  -48.023 1.00 49.22  ? 118 GLY H C   1 
ATOM   931  O O   . GLY A 1 124 ? 45.321  15.332  -49.028 1.00 49.46  ? 118 GLY H O   1 
ATOM   932  N N   . PRO A 1 125 ? 44.162  16.981  -48.044 1.00 55.19  ? 119 PRO H N   1 
ATOM   933  C CA  . PRO A 1 125 ? 44.131  17.774  -49.277 1.00 46.46  ? 119 PRO H CA  1 
ATOM   934  C C   . PRO A 1 125 ? 45.499  18.320  -49.645 1.00 49.81  ? 119 PRO H C   1 
ATOM   935  O O   . PRO A 1 125 ? 46.348  18.580  -48.788 1.00 60.72  ? 119 PRO H O   1 
ATOM   936  C CB  . PRO A 1 125 ? 43.159  18.911  -48.940 1.00 35.54  ? 119 PRO H CB  1 
ATOM   937  C CG  . PRO A 1 125 ? 43.227  19.033  -47.459 1.00 27.94  ? 119 PRO H CG  1 
ATOM   938  C CD  . PRO A 1 125 ? 43.428  17.634  -46.948 1.00 44.38  ? 119 PRO H CD  1 
ATOM   939  N N   . SER A 1 126 ? 45.699  18.498  -50.946 1.00 42.51  ? 120 SER H N   1 
ATOM   940  C CA  . SER A 1 126 ? 46.863  19.187  -51.488 1.00 35.32  ? 120 SER H CA  1 
ATOM   941  C C   . SER A 1 126 ? 46.414  20.541  -52.015 1.00 44.82  ? 120 SER H C   1 
ATOM   942  O O   . SER A 1 126 ? 45.503  20.616  -52.847 1.00 42.74  ? 120 SER H O   1 
ATOM   943  C CB  . SER A 1 126 ? 47.519  18.371  -52.603 1.00 33.05  ? 120 SER H CB  1 
ATOM   944  O OG  . SER A 1 126 ? 47.857  17.072  -52.151 1.00 67.05  ? 120 SER H OG  1 
ATOM   945  N N   . VAL A 1 127 ? 47.048  21.604  -51.532 1.00 47.48  ? 121 VAL H N   1 
ATOM   946  C CA  . VAL A 1 127 ? 46.638  22.969  -51.836 1.00 29.95  ? 121 VAL H CA  1 
ATOM   947  C C   . VAL A 1 127 ? 47.667  23.583  -52.774 1.00 39.64  ? 121 VAL H C   1 
ATOM   948  O O   . VAL A 1 127 ? 48.863  23.620  -52.459 1.00 43.25  ? 121 VAL H O   1 
ATOM   949  C CB  . VAL A 1 127 ? 46.480  23.807  -50.559 1.00 34.21  ? 121 VAL H CB  1 
ATOM   950  C CG1 . VAL A 1 127 ? 45.906  25.174  -50.890 1.00 37.71  ? 121 VAL H CG1 1 
ATOM   951  C CG2 . VAL A 1 127 ? 45.596  23.074  -49.564 1.00 33.58  ? 121 VAL H CG2 1 
ATOM   952  N N   . PHE A 1 128 ? 47.199  24.067  -53.923 1.00 41.36  ? 122 PHE H N   1 
ATOM   953  C CA  . PHE A 1 128 ? 48.050  24.695  -54.916 1.00 40.12  ? 122 PHE H CA  1 
ATOM   954  C C   . PHE A 1 128 ? 47.520  26.086  -55.236 1.00 44.32  ? 122 PHE H C   1 
ATOM   955  O O   . PHE A 1 128 ? 46.303  26.283  -55.329 1.00 48.10  ? 122 PHE H O   1 
ATOM   956  C CB  . PHE A 1 128 ? 48.115  23.850  -56.196 1.00 35.07  ? 122 PHE H CB  1 
ATOM   957  C CG  . PHE A 1 128 ? 48.426  22.401  -55.950 1.00 43.33  ? 122 PHE H CG  1 
ATOM   958  C CD1 . PHE A 1 128 ? 49.693  22.010  -55.548 1.00 52.93  ? 122 PHE H CD1 1 
ATOM   959  C CD2 . PHE A 1 128 ? 47.454  21.430  -56.122 1.00 39.37  ? 122 PHE H CD2 1 
ATOM   960  C CE1 . PHE A 1 128 ? 49.983  20.677  -55.320 1.00 53.43  ? 122 PHE H CE1 1 
ATOM   961  C CE2 . PHE A 1 128 ? 47.738  20.096  -55.897 1.00 42.10  ? 122 PHE H CE2 1 
ATOM   962  C CZ  . PHE A 1 128 ? 49.004  19.719  -55.496 1.00 44.85  ? 122 PHE H CZ  1 
ATOM   963  N N   . PRO A 1 129 ? 48.404  27.066  -55.407 1.00 49.73  ? 123 PRO H N   1 
ATOM   964  C CA  . PRO A 1 129 ? 47.947  28.441  -55.637 1.00 47.30  ? 123 PRO H CA  1 
ATOM   965  C C   . PRO A 1 129 ? 47.468  28.664  -57.063 1.00 37.24  ? 123 PRO H C   1 
ATOM   966  O O   . PRO A 1 129 ? 47.999  28.094  -58.019 1.00 44.10  ? 123 PRO H O   1 
ATOM   967  C CB  . PRO A 1 129 ? 49.197  29.276  -55.340 1.00 59.49  ? 123 PRO H CB  1 
ATOM   968  C CG  . PRO A 1 129 ? 50.331  28.364  -55.679 1.00 50.68  ? 123 PRO H CG  1 
ATOM   969  C CD  . PRO A 1 129 ? 49.872  26.975  -55.313 1.00 50.25  ? 123 PRO H CD  1 
ATOM   970  N N   . LEU A 1 130 ? 46.447  29.508  -57.196 1.00 34.98  ? 124 LEU H N   1 
ATOM   971  C CA  . LEU A 1 130 ? 45.980  29.994  -58.494 1.00 41.58  ? 124 LEU H CA  1 
ATOM   972  C C   . LEU A 1 130 ? 46.459  31.437  -58.616 1.00 48.78  ? 124 LEU H C   1 
ATOM   973  O O   . LEU A 1 130 ? 45.769  32.379  -58.222 1.00 40.33  ? 124 LEU H O   1 
ATOM   974  C CB  . LEU A 1 130 ? 44.465  29.880  -58.618 1.00 45.21  ? 124 LEU H CB  1 
ATOM   975  C CG  . LEU A 1 130 ? 43.870  28.471  -58.645 1.00 44.95  ? 124 LEU H CG  1 
ATOM   976  C CD1 . LEU A 1 130 ? 42.352  28.534  -58.607 1.00 37.62  ? 124 LEU H CD1 1 
ATOM   977  C CD2 . LEU A 1 130 ? 44.344  27.709  -59.874 1.00 39.75  ? 124 LEU H CD2 1 
ATOM   978  N N   . ALA A 1 131 ? 47.661  31.603  -59.161 1.00 53.54  ? 125 ALA H N   1 
ATOM   979  C CA  . ALA A 1 131 ? 48.308  32.906  -59.162 1.00 45.22  ? 125 ALA H CA  1 
ATOM   980  C C   . ALA A 1 131 ? 47.583  33.873  -60.096 1.00 41.53  ? 125 ALA H C   1 
ATOM   981  O O   . ALA A 1 131 ? 47.105  33.471  -61.161 1.00 44.10  ? 125 ALA H O   1 
ATOM   982  C CB  . ALA A 1 131 ? 49.771  32.778  -59.582 1.00 38.52  ? 125 ALA H CB  1 
ATOM   983  N N   . PRO A 1 132 ? 47.483  35.147  -59.725 1.00 51.83  ? 126 PRO H N   1 
ATOM   984  C CA  . PRO A 1 132 ? 46.932  36.145  -60.646 1.00 44.42  ? 126 PRO H CA  1 
ATOM   985  C C   . PRO A 1 132 ? 47.854  36.358  -61.835 1.00 60.71  ? 126 PRO H C   1 
ATOM   986  O O   . PRO A 1 132 ? 49.063  36.123  -61.775 1.00 68.50  ? 126 PRO H O   1 
ATOM   987  C CB  . PRO A 1 132 ? 46.833  37.414  -59.790 1.00 44.73  ? 126 PRO H CB  1 
ATOM   988  C CG  . PRO A 1 132 ? 46.954  36.950  -58.372 1.00 50.18  ? 126 PRO H CG  1 
ATOM   989  C CD  . PRO A 1 132 ? 47.811  35.726  -58.413 1.00 53.24  ? 126 PRO H CD  1 
ATOM   990  N N   . SER A 1 133 ? 47.260  36.817  -62.933 1.00 57.61  ? 127 SER H N   1 
ATOM   991  C CA  . SER A 1 133 ? 47.999  37.046  -64.166 1.00 61.10  ? 127 SER H CA  1 
ATOM   992  C C   . SER A 1 133 ? 47.275  38.106  -64.982 1.00 66.14  ? 127 SER H C   1 
ATOM   993  O O   . SER A 1 133 ? 46.197  38.580  -64.611 1.00 61.90  ? 127 SER H O   1 
ATOM   994  C CB  . SER A 1 133 ? 48.158  35.746  -64.962 1.00 63.31  ? 127 SER H CB  1 
ATOM   995  O OG  . SER A 1 133 ? 48.749  35.994  -66.225 1.00 82.11  ? 127 SER H OG  1 
ATOM   996  N N   . SER A 1 134 ? 47.887  38.488  -66.105 1.00 75.05  ? 128 SER H N   1 
ATOM   997  C CA  . SER A 1 134 ? 47.198  39.340  -67.065 1.00 78.72  ? 128 SER H CA  1 
ATOM   998  C C   . SER A 1 134 ? 46.008  38.627  -67.692 1.00 94.14  ? 128 SER H C   1 
ATOM   999  O O   . SER A 1 134 ? 45.146  39.281  -68.288 1.00 100.44 ? 128 SER H O   1 
ATOM   1000 C CB  . SER A 1 134 ? 48.168  39.807  -68.151 1.00 74.63  ? 128 SER H CB  1 
ATOM   1001 O OG  . SER A 1 134 ? 48.771  38.703  -68.802 1.00 83.97  ? 128 SER H OG  1 
ATOM   1002 N N   . LYS A 1 135 ? 45.948  37.301  -67.573 1.00 86.31  ? 129 LYS H N   1 
ATOM   1003 C CA  . LYS A 1 135 ? 44.795  36.531  -68.015 1.00 73.39  ? 129 LYS H CA  1 
ATOM   1004 C C   . LYS A 1 135 ? 43.658  36.548  -67.003 1.00 69.68  ? 129 LYS H C   1 
ATOM   1005 O O   . LYS A 1 135 ? 42.586  36.006  -67.291 1.00 65.20  ? 129 LYS H O   1 
ATOM   1006 C CB  . LYS A 1 135 ? 45.212  35.084  -68.296 1.00 59.71  ? 129 LYS H CB  1 
ATOM   1007 C CG  . LYS A 1 135 ? 46.524  34.952  -69.060 1.00 55.18  ? 129 LYS H CG  1 
ATOM   1008 C CD  . LYS A 1 135 ? 46.310  34.405  -70.464 1.00 55.05  ? 129 LYS H CD  1 
ATOM   1009 C CE  . LYS A 1 135 ? 45.536  35.381  -71.335 1.00 63.91  ? 129 LYS H CE  1 
ATOM   1010 N NZ  . LYS A 1 135 ? 45.333  34.858  -72.714 1.00 68.94  ? 129 LYS H NZ  1 
ATOM   1011 N N   . SER A 1 136 ? 43.868  37.143  -65.830 1.00 80.75  ? 130 SER H N   1 
ATOM   1012 C CA  . SER A 1 136 ? 42.844  37.223  -64.795 1.00 72.83  ? 130 SER H CA  1 
ATOM   1013 C C   . SER A 1 136 ? 42.832  38.606  -64.159 1.00 68.30  ? 130 SER H C   1 
ATOM   1014 O O   . SER A 1 136 ? 42.745  38.744  -62.934 1.00 59.31  ? 130 SER H O   1 
ATOM   1015 C CB  . SER A 1 136 ? 43.050  36.145  -63.731 1.00 50.46  ? 130 SER H CB  1 
ATOM   1016 O OG  . SER A 1 136 ? 44.290  36.313  -63.065 1.00 45.49  ? 130 SER H OG  1 
ATOM   1017 N N   . THR A 1 137 ? 42.918  39.654  -64.978 1.00 71.88  ? 131 THR H N   1 
ATOM   1018 C CA  . THR A 1 137 ? 42.941  41.023  -64.473 1.00 71.57  ? 131 THR H CA  1 
ATOM   1019 C C   . THR A 1 137 ? 41.696  41.827  -64.817 1.00 61.94  ? 131 THR H C   1 
ATOM   1020 O O   . THR A 1 137 ? 41.248  42.621  -63.990 1.00 76.87  ? 131 THR H O   1 
ATOM   1021 C CB  . THR A 1 137 ? 44.184  41.765  -64.986 1.00 80.44  ? 131 THR H CB  1 
ATOM   1022 O OG1 . THR A 1 137 ? 44.173  43.114  -64.499 1.00 67.24  ? 131 THR H OG1 1 
ATOM   1023 C CG2 . THR A 1 137 ? 44.231  41.779  -66.510 1.00 84.60  ? 131 THR H CG2 1 
ATOM   1024 N N   . SER A 1 138 ? 41.135  41.645  -66.013 1.00 52.90  ? 132 SER H N   1 
ATOM   1025 C CA  . SER A 1 138 ? 39.899  42.308  -66.447 1.00 67.67  ? 132 SER H CA  1 
ATOM   1026 C C   . SER A 1 138 ? 39.881  43.788  -66.067 1.00 75.47  ? 132 SER H C   1 
ATOM   1027 O O   . SER A 1 138 ? 38.914  44.305  -65.502 1.00 59.03  ? 132 SER H O   1 
ATOM   1028 C CB  . SER A 1 138 ? 38.673  41.589  -65.887 1.00 67.10  ? 132 SER H CB  1 
ATOM   1029 O OG  . SER A 1 138 ? 37.475  42.176  -66.368 1.00 53.38  ? 132 SER H OG  1 
ATOM   1030 N N   . GLY A 1 139 ? 40.976  44.477  -66.379 1.00 91.04  ? 133 GLY H N   1 
ATOM   1031 C CA  . GLY A 1 139 ? 41.086  45.887  -66.062 1.00 79.69  ? 133 GLY H CA  1 
ATOM   1032 C C   . GLY A 1 139 ? 41.497  46.154  -64.628 1.00 70.20  ? 133 GLY H C   1 
ATOM   1033 O O   . GLY A 1 139 ? 42.649  45.915  -64.252 1.00 60.73  ? 133 GLY H O   1 
ATOM   1034 N N   . GLY A 1 140 ? 40.566  46.650  -63.817 1.00 46.70  ? 134 GLY H N   1 
ATOM   1035 C CA  . GLY A 1 140 ? 40.868  46.978  -62.437 1.00 61.18  ? 134 GLY H CA  1 
ATOM   1036 C C   . GLY A 1 140 ? 40.232  46.039  -61.432 1.00 67.50  ? 134 GLY H C   1 
ATOM   1037 O O   . GLY A 1 140 ? 39.870  46.457  -60.328 1.00 66.44  ? 134 GLY H O   1 
ATOM   1038 N N   . THR A 1 141 ? 40.089  44.764  -61.802 1.00 78.16  ? 135 THR H N   1 
ATOM   1039 C CA  . THR A 1 141 ? 39.435  43.782  -60.934 1.00 65.04  ? 135 THR H CA  1 
ATOM   1040 C C   . THR A 1 141 ? 40.089  42.422  -61.191 1.00 55.57  ? 135 THR H C   1 
ATOM   1041 O O   . THR A 1 141 ? 39.660  41.671  -62.070 1.00 63.48  ? 135 THR H O   1 
ATOM   1042 C CB  . THR A 1 141 ? 37.935  43.741  -61.188 1.00 58.68  ? 135 THR H CB  1 
ATOM   1043 O OG1 . THR A 1 141 ? 37.380  45.050  -61.011 1.00 75.62  ? 135 THR H OG1 1 
ATOM   1044 C CG2 . THR A 1 141 ? 37.260  42.788  -60.231 1.00 55.04  ? 135 THR H CG2 1 
ATOM   1045 N N   . ALA A 1 142 ? 41.106  42.106  -60.396 1.00 46.81  ? 136 ALA H N   1 
ATOM   1046 C CA  . ALA A 1 142 ? 41.878  40.886  -60.577 1.00 51.54  ? 136 ALA H CA  1 
ATOM   1047 C C   . ALA A 1 142 ? 41.256  39.722  -59.811 1.00 49.09  ? 136 ALA H C   1 
ATOM   1048 O O   . ALA A 1 142 ? 40.535  39.903  -58.827 1.00 55.09  ? 136 ALA H O   1 
ATOM   1049 C CB  . ALA A 1 142 ? 43.325  41.093  -60.129 1.00 50.19  ? 136 ALA H CB  1 
ATOM   1050 N N   . ALA A 1 143 ? 41.553  38.509  -60.278 1.00 37.53  ? 137 ALA H N   1 
ATOM   1051 C CA  . ALA A 1 143 ? 41.011  37.290  -59.696 1.00 39.13  ? 137 ALA H CA  1 
ATOM   1052 C C   . ALA A 1 143 ? 42.137  36.325  -59.355 1.00 44.16  ? 137 ALA H C   1 
ATOM   1053 O O   . ALA A 1 143 ? 43.089  36.164  -60.126 1.00 43.44  ? 137 ALA H O   1 
ATOM   1054 C CB  . ALA A 1 143 ? 40.014  36.615  -60.644 1.00 40.97  ? 137 ALA H CB  1 
ATOM   1055 N N   . LEU A 1 144 ? 42.015  35.682  -58.196 1.00 34.26  ? 138 LEU H N   1 
ATOM   1056 C CA  . LEU A 1 144 ? 42.978  34.694  -57.734 1.00 32.73  ? 138 LEU H CA  1 
ATOM   1057 C C   . LEU A 1 144 ? 42.236  33.671  -56.888 1.00 36.56  ? 138 LEU H C   1 
ATOM   1058 O O   . LEU A 1 144 ? 41.072  33.864  -56.528 1.00 30.82  ? 138 LEU H O   1 
ATOM   1059 C CB  . LEU A 1 144 ? 44.116  35.335  -56.933 1.00 36.44  ? 138 LEU H CB  1 
ATOM   1060 C CG  . LEU A 1 144 ? 43.740  36.073  -55.645 1.00 27.55  ? 138 LEU H CG  1 
ATOM   1061 C CD1 . LEU A 1 144 ? 44.889  36.037  -54.659 1.00 41.45  ? 138 LEU H CD1 1 
ATOM   1062 C CD2 . LEU A 1 144 ? 43.355  37.510  -55.937 1.00 38.59  ? 138 LEU H CD2 1 
ATOM   1063 N N   . GLY A 1 145 ? 42.917  32.579  -56.567 1.00 42.40  ? 139 GLY H N   1 
ATOM   1064 C CA  . GLY A 1 145 ? 42.269  31.551  -55.781 1.00 39.64  ? 139 GLY H CA  1 
ATOM   1065 C C   . GLY A 1 145 ? 43.228  30.464  -55.354 1.00 36.95  ? 139 GLY H C   1 
ATOM   1066 O O   . GLY A 1 145 ? 44.444  30.578  -55.512 1.00 43.07  ? 139 GLY H O   1 
ATOM   1067 N N   . CYS A 1 146 ? 42.650  29.402  -54.795 1.00 44.26  ? 140 CYS H N   1 
ATOM   1068 C CA  . CYS A 1 146 ? 43.396  28.240  -54.341 1.00 45.75  ? 140 CYS H CA  1 
ATOM   1069 C C   . CYS A 1 146 ? 42.714  26.968  -54.824 1.00 41.20  ? 140 CYS H C   1 
ATOM   1070 O O   . CYS A 1 146 ? 41.485  26.894  -54.903 1.00 45.21  ? 140 CYS H O   1 
ATOM   1071 C CB  . CYS A 1 146 ? 43.519  28.214  -52.813 1.00 39.86  ? 140 CYS H CB  1 
ATOM   1072 S SG  . CYS A 1 146 ? 44.793  29.309  -52.168 1.00 89.00  ? 140 CYS H SG  1 
ATOM   1073 N N   . LEU A 1 147 ? 43.530  25.967  -55.142 1.00 39.98  ? 141 LEU H N   1 
ATOM   1074 C CA  . LEU A 1 147 ? 43.058  24.670  -55.609 1.00 34.20  ? 141 LEU H CA  1 
ATOM   1075 C C   . LEU A 1 147 ? 43.271  23.644  -54.503 1.00 36.55  ? 141 LEU H C   1 
ATOM   1076 O O   . LEU A 1 147 ? 44.413  23.355  -54.130 1.00 45.44  ? 141 LEU H O   1 
ATOM   1077 C CB  . LEU A 1 147 ? 43.790  24.256  -56.886 1.00 26.66  ? 141 LEU H CB  1 
ATOM   1078 C CG  . LEU A 1 147 ? 43.464  22.887  -57.486 1.00 37.42  ? 141 LEU H CG  1 
ATOM   1079 C CD1 . LEU A 1 147 ? 41.977  22.745  -57.745 1.00 34.36  ? 141 LEU H CD1 1 
ATOM   1080 C CD2 . LEU A 1 147 ? 44.252  22.679  -58.768 1.00 34.42  ? 141 LEU H CD2 1 
ATOM   1081 N N   . VAL A 1 148 ? 42.174  23.103  -53.981 1.00 27.08  ? 142 VAL H N   1 
ATOM   1082 C CA  . VAL A 1 148 ? 42.199  22.106  -52.916 1.00 37.99  ? 142 VAL H CA  1 
ATOM   1083 C C   . VAL A 1 148 ? 41.826  20.770  -53.543 1.00 43.93  ? 142 VAL H C   1 
ATOM   1084 O O   . VAL A 1 148 ? 40.658  20.535  -53.878 1.00 44.98  ? 142 VAL H O   1 
ATOM   1085 C CB  . VAL A 1 148 ? 41.243  22.476  -51.774 1.00 38.37  ? 142 VAL H CB  1 
ATOM   1086 C CG1 . VAL A 1 148 ? 41.362  21.480  -50.637 1.00 47.31  ? 142 VAL H CG1 1 
ATOM   1087 C CG2 . VAL A 1 148 ? 41.523  23.890  -51.289 1.00 32.09  ? 142 VAL H CG2 1 
ATOM   1088 N N   . LYS A 1 149 ? 42.809  19.884  -53.689 1.00 36.12  ? 143 LYS H N   1 
ATOM   1089 C CA  . LYS A 1 149 ? 42.659  18.700  -54.521 1.00 40.12  ? 143 LYS H CA  1 
ATOM   1090 C C   . LYS A 1 149 ? 42.970  17.432  -53.736 1.00 40.16  ? 143 LYS H C   1 
ATOM   1091 O O   . LYS A 1 149 ? 43.846  17.414  -52.868 1.00 40.52  ? 143 LYS H O   1 
ATOM   1092 C CB  . LYS A 1 149 ? 43.575  18.784  -55.754 1.00 30.45  ? 143 LYS H CB  1 
ATOM   1093 C CG  . LYS A 1 149 ? 43.229  17.814  -56.870 1.00 56.27  ? 143 LYS H CG  1 
ATOM   1094 C CD  . LYS A 1 149 ? 44.169  17.985  -58.052 1.00 53.24  ? 143 LYS H CD  1 
ATOM   1095 C CE  . LYS A 1 149 ? 43.787  17.072  -59.206 1.00 55.33  ? 143 LYS H CE  1 
ATOM   1096 N NZ  . LYS A 1 149 ? 42.439  17.398  -59.748 1.00 63.75  ? 143 LYS H NZ  1 
ATOM   1097 N N   . ASP A 1 150 ? 42.233  16.368  -54.067 1.00 53.06  ? 144 ASP H N   1 
ATOM   1098 C CA  . ASP A 1 150 ? 42.520  14.999  -53.633 1.00 46.83  ? 144 ASP H CA  1 
ATOM   1099 C C   . ASP A 1 150 ? 42.501  14.875  -52.105 1.00 45.06  ? 144 ASP H C   1 
ATOM   1100 O O   . ASP A 1 150 ? 43.511  14.605  -51.454 1.00 60.60  ? 144 ASP H O   1 
ATOM   1101 C CB  . ASP A 1 150 ? 43.858  14.525  -54.213 1.00 45.82  ? 144 ASP H CB  1 
ATOM   1102 C CG  . ASP A 1 150 ? 43.837  14.438  -55.728 1.00 57.69  ? 144 ASP H CG  1 
ATOM   1103 O OD1 . ASP A 1 150 ? 42.792  14.043  -56.287 1.00 57.62  ? 144 ASP H OD1 1 
ATOM   1104 O OD2 . ASP A 1 150 ? 44.862  14.772  -56.359 1.00 60.04  ? 144 ASP H OD2 1 
ATOM   1105 N N   . TYR A 1 151 ? 41.308  15.077  -51.548 1.00 37.26  ? 145 TYR H N   1 
ATOM   1106 C CA  . TYR A 1 151 ? 41.080  14.876  -50.125 1.00 41.41  ? 145 TYR H CA  1 
ATOM   1107 C C   . TYR A 1 151 ? 39.846  14.011  -49.910 1.00 47.59  ? 145 TYR H C   1 
ATOM   1108 O O   . TYR A 1 151 ? 38.941  13.954  -50.748 1.00 41.21  ? 145 TYR H O   1 
ATOM   1109 C CB  . TYR A 1 151 ? 40.916  16.206  -49.373 1.00 37.90  ? 145 TYR H CB  1 
ATOM   1110 C CG  . TYR A 1 151 ? 39.682  16.992  -49.747 1.00 32.91  ? 145 TYR H CG  1 
ATOM   1111 C CD1 . TYR A 1 151 ? 39.717  17.931  -50.768 1.00 34.46  ? 145 TYR H CD1 1 
ATOM   1112 C CD2 . TYR A 1 151 ? 38.483  16.804  -49.071 1.00 32.11  ? 145 TYR H CD2 1 
ATOM   1113 C CE1 . TYR A 1 151 ? 38.594  18.654  -51.111 1.00 41.07  ? 145 TYR H CE1 1 
ATOM   1114 C CE2 . TYR A 1 151 ? 37.355  17.520  -49.407 1.00 33.84  ? 145 TYR H CE2 1 
ATOM   1115 C CZ  . TYR A 1 151 ? 37.415  18.444  -50.427 1.00 39.05  ? 145 TYR H CZ  1 
ATOM   1116 O OH  . TYR A 1 151 ? 36.293  19.165  -50.765 1.00 31.87  ? 145 TYR H OH  1 
ATOM   1117 N N   . PHE A 1 152 ? 39.824  13.336  -48.759 1.00 47.76  ? 146 PHE H N   1 
ATOM   1118 C CA  . PHE A 1 152 ? 38.685  12.541  -48.326 1.00 37.79  ? 146 PHE H CA  1 
ATOM   1119 C C   . PHE A 1 152 ? 38.761  12.403  -46.817 1.00 44.57  ? 146 PHE H C   1 
ATOM   1120 O O   . PHE A 1 152 ? 39.866  12.238  -46.283 1.00 58.64  ? 146 PHE H O   1 
ATOM   1121 C CB  . PHE A 1 152 ? 38.672  11.158  -48.990 1.00 45.75  ? 146 PHE H CB  1 
ATOM   1122 C CG  . PHE A 1 152 ? 37.505  10.299  -48.585 1.00 40.09  ? 146 PHE H CG  1 
ATOM   1123 C CD1 . PHE A 1 152 ? 36.300  10.378  -49.263 1.00 38.57  ? 146 PHE H CD1 1 
ATOM   1124 C CD2 . PHE A 1 152 ? 37.614  9.413   -47.525 1.00 44.31  ? 146 PHE H CD2 1 
ATOM   1125 C CE1 . PHE A 1 152 ? 35.225  9.591   -48.891 1.00 33.27  ? 146 PHE H CE1 1 
ATOM   1126 C CE2 . PHE A 1 152 ? 36.543  8.625   -47.149 1.00 47.25  ? 146 PHE H CE2 1 
ATOM   1127 C CZ  . PHE A 1 152 ? 35.348  8.713   -47.833 1.00 41.19  ? 146 PHE H CZ  1 
ATOM   1128 N N   . PRO A 1 153 ? 37.634  12.478  -46.098 1.00 48.00  ? 147 PRO H N   1 
ATOM   1129 C CA  . PRO A 1 153 ? 36.282  12.759  -46.586 1.00 41.44  ? 147 PRO H CA  1 
ATOM   1130 C C   . PRO A 1 153 ? 35.954  14.244  -46.526 1.00 46.44  ? 147 PRO H C   1 
ATOM   1131 O O   . PRO A 1 153 ? 36.797  15.066  -46.177 1.00 50.82  ? 147 PRO H O   1 
ATOM   1132 C CB  . PRO A 1 153 ? 35.412  11.944  -45.628 1.00 34.40  ? 147 PRO H CB  1 
ATOM   1133 C CG  . PRO A 1 153 ? 36.142  12.074  -44.315 1.00 54.12  ? 147 PRO H CG  1 
ATOM   1134 C CD  . PRO A 1 153 ? 37.621  12.109  -44.670 1.00 56.06  ? 147 PRO H CD  1 
ATOM   1135 N N   . GLU A 1 154 ? 34.725  14.607  -46.875 1.00 47.54  ? 148 GLU H N   1 
ATOM   1136 C CA  . GLU A 1 154 ? 34.264  15.969  -46.693 1.00 44.02  ? 148 GLU H CA  1 
ATOM   1137 C C   . GLU A 1 154 ? 34.023  16.244  -45.209 1.00 46.32  ? 148 GLU H C   1 
ATOM   1138 O O   . GLU A 1 154 ? 33.833  15.315  -44.420 1.00 52.75  ? 148 GLU H O   1 
ATOM   1139 C CB  . GLU A 1 154 ? 32.989  16.202  -47.499 1.00 36.13  ? 148 GLU H CB  1 
ATOM   1140 C CG  . GLU A 1 154 ? 33.228  16.412  -48.982 1.00 33.20  ? 148 GLU H CG  1 
ATOM   1141 C CD  . GLU A 1 154 ? 31.938  16.599  -49.754 1.00 56.47  ? 148 GLU H CD  1 
ATOM   1142 O OE1 . GLU A 1 154 ? 31.097  15.673  -49.741 1.00 50.24  ? 148 GLU H OE1 1 
ATOM   1143 O OE2 . GLU A 1 154 ? 31.759  17.676  -50.363 1.00 51.63  ? 148 GLU H OE2 1 
ATOM   1144 N N   . PRO A 1 155 ? 34.028  17.522  -44.797 1.00 46.76  ? 149 PRO H N   1 
ATOM   1145 C CA  . PRO A 1 155 ? 34.238  18.740  -45.585 1.00 40.69  ? 149 PRO H CA  1 
ATOM   1146 C C   . PRO A 1 155 ? 35.584  19.422  -45.352 1.00 39.71  ? 149 PRO H C   1 
ATOM   1147 O O   . PRO A 1 155 ? 36.278  19.156  -44.374 1.00 47.75  ? 149 PRO H O   1 
ATOM   1148 C CB  . PRO A 1 155 ? 33.080  19.627  -45.112 1.00 34.11  ? 149 PRO H CB  1 
ATOM   1149 C CG  . PRO A 1 155 ? 32.811  19.179  -43.661 1.00 22.19  ? 149 PRO H CG  1 
ATOM   1150 C CD  . PRO A 1 155 ? 33.540  17.863  -43.452 1.00 35.05  ? 149 PRO H CD  1 
ATOM   1151 N N   . VAL A 1 156 ? 35.970  20.315  -46.260 1.00 34.97  ? 150 VAL H N   1 
ATOM   1152 C CA  . VAL A 1 156 ? 37.118  21.191  -46.070 1.00 31.82  ? 150 VAL H CA  1 
ATOM   1153 C C   . VAL A 1 156 ? 36.606  22.607  -45.863 1.00 34.80  ? 150 VAL H C   1 
ATOM   1154 O O   . VAL A 1 156 ? 35.585  23.012  -46.430 1.00 38.09  ? 150 VAL H O   1 
ATOM   1155 C CB  . VAL A 1 156 ? 38.109  21.146  -47.253 1.00 37.82  ? 150 VAL H CB  1 
ATOM   1156 C CG1 . VAL A 1 156 ? 38.862  19.833  -47.270 1.00 42.97  ? 150 VAL H CG1 1 
ATOM   1157 C CG2 . VAL A 1 156 ? 37.379  21.370  -48.569 1.00 37.95  ? 150 VAL H CG2 1 
ATOM   1158 N N   . THR A 1 157 ? 37.322  23.361  -45.038 1.00 48.57  ? 151 THR H N   1 
ATOM   1159 C CA  . THR A 1 157 ? 37.001  24.754  -44.761 1.00 44.51  ? 151 THR H CA  1 
ATOM   1160 C C   . THR A 1 157 ? 38.071  25.641  -45.378 1.00 50.24  ? 151 THR H C   1 
ATOM   1161 O O   . THR A 1 157 ? 39.263  25.462  -45.107 1.00 65.13  ? 151 THR H O   1 
ATOM   1162 C CB  . THR A 1 157 ? 36.903  25.008  -43.255 1.00 47.73  ? 151 THR H CB  1 
ATOM   1163 O OG1 . THR A 1 157 ? 35.756  24.328  -42.728 1.00 44.87  ? 151 THR H OG1 1 
ATOM   1164 C CG2 . THR A 1 157 ? 36.780  26.498  -42.970 1.00 54.09  ? 151 THR H CG2 1 
ATOM   1165 N N   . VAL A 1 158 ? 37.646  26.590  -46.208 1.00 41.94  ? 152 VAL H N   1 
ATOM   1166 C CA  . VAL A 1 158 ? 38.549  27.503  -46.895 1.00 48.64  ? 152 VAL H CA  1 
ATOM   1167 C C   . VAL A 1 158 ? 38.231  28.923  -46.451 1.00 50.38  ? 152 VAL H C   1 
ATOM   1168 O O   . VAL A 1 158 ? 37.083  29.370  -46.553 1.00 41.51  ? 152 VAL H O   1 
ATOM   1169 C CB  . VAL A 1 158 ? 38.442  27.370  -48.424 1.00 32.50  ? 152 VAL H CB  1 
ATOM   1170 C CG1 . VAL A 1 158 ? 39.365  28.364  -49.103 1.00 25.16  ? 152 VAL H CG1 1 
ATOM   1171 C CG2 . VAL A 1 158 ? 38.773  25.949  -48.855 1.00 45.26  ? 152 VAL H CG2 1 
ATOM   1172 N N   . SER A 1 159 ? 39.249  29.627  -45.962 1.00 59.33  ? 153 SER H N   1 
ATOM   1173 C CA  . SER A 1 159 ? 39.125  31.013  -45.543 1.00 44.57  ? 153 SER H CA  1 
ATOM   1174 C C   . SER A 1 159 ? 40.224  31.830  -46.205 1.00 43.83  ? 153 SER H C   1 
ATOM   1175 O O   . SER A 1 159 ? 41.294  31.310  -46.530 1.00 52.38  ? 153 SER H O   1 
ATOM   1176 C CB  . SER A 1 159 ? 39.216  31.154  -44.017 1.00 49.36  ? 153 SER H CB  1 
ATOM   1177 O OG  . SER A 1 159 ? 38.238  30.357  -43.371 1.00 64.64  ? 153 SER H OG  1 
ATOM   1178 N N   . TRP A 1 160 ? 39.950  33.115  -46.406 1.00 49.23  ? 154 TRP H N   1 
ATOM   1179 C CA  . TRP A 1 160 ? 40.904  34.037  -47.008 1.00 54.82  ? 154 TRP H CA  1 
ATOM   1180 C C   . TRP A 1 160 ? 41.329  35.065  -45.968 1.00 56.59  ? 154 TRP H C   1 
ATOM   1181 O O   . TRP A 1 160 ? 40.481  35.748  -45.383 1.00 59.57  ? 154 TRP H O   1 
ATOM   1182 C CB  . TRP A 1 160 ? 40.306  34.718  -48.238 1.00 44.57  ? 154 TRP H CB  1 
ATOM   1183 C CG  . TRP A 1 160 ? 40.250  33.816  -49.430 1.00 46.14  ? 154 TRP H CG  1 
ATOM   1184 C CD1 . TRP A 1 160 ? 39.184  33.077  -49.850 1.00 37.31  ? 154 TRP H CD1 1 
ATOM   1185 C CD2 . TRP A 1 160 ? 41.314  33.544  -50.351 1.00 54.09  ? 154 TRP H CD2 1 
ATOM   1186 N NE1 . TRP A 1 160 ? 39.515  32.367  -50.979 1.00 37.90  ? 154 TRP H NE1 1 
ATOM   1187 C CE2 . TRP A 1 160 ? 40.818  32.636  -51.307 1.00 43.40  ? 154 TRP H CE2 1 
ATOM   1188 C CE3 . TRP A 1 160 ? 42.637  33.983  -50.460 1.00 52.30  ? 154 TRP H CE3 1 
ATOM   1189 C CZ2 . TRP A 1 160 ? 41.598  32.159  -52.358 1.00 44.68  ? 154 TRP H CZ2 1 
ATOM   1190 C CZ3 . TRP A 1 160 ? 43.410  33.509  -51.505 1.00 46.52  ? 154 TRP H CZ3 1 
ATOM   1191 C CH2 . TRP A 1 160 ? 42.888  32.607  -52.440 1.00 45.26  ? 154 TRP H CH2 1 
ATOM   1192 N N   . ASN A 1 161 ? 42.642  35.171  -45.750 1.00 55.09  ? 155 ASN H N   1 
ATOM   1193 C CA  . ASN A 1 161 ? 43.222  36.091  -44.769 1.00 53.54  ? 155 ASN H CA  1 
ATOM   1194 C C   . ASN A 1 161 ? 42.653  35.843  -43.371 1.00 50.60  ? 155 ASN H C   1 
ATOM   1195 O O   . ASN A 1 161 ? 42.244  36.769  -42.667 1.00 53.47  ? 155 ASN H O   1 
ATOM   1196 C CB  . ASN A 1 161 ? 43.026  37.547  -45.199 1.00 44.84  ? 155 ASN H CB  1 
ATOM   1197 C CG  . ASN A 1 161 ? 43.704  37.861  -46.520 1.00 52.11  ? 155 ASN H CG  1 
ATOM   1198 O OD1 . ASN A 1 161 ? 44.635  37.169  -46.933 1.00 49.71  ? 155 ASN H OD1 1 
ATOM   1199 N ND2 . ASN A 1 161 ? 43.241  38.911  -47.189 1.00 55.17  ? 155 ASN H ND2 1 
ATOM   1200 N N   . SER A 1 162 ? 42.630  34.568  -42.976 1.00 49.09  ? 156 SER H N   1 
ATOM   1201 C CA  . SER A 1 162 ? 42.189  34.151  -41.643 1.00 51.16  ? 156 SER H CA  1 
ATOM   1202 C C   . SER A 1 162 ? 40.770  34.632  -41.342 1.00 47.11  ? 156 SER H C   1 
ATOM   1203 O O   . SER A 1 162 ? 40.455  35.040  -40.222 1.00 45.09  ? 156 SER H O   1 
ATOM   1204 C CB  . SER A 1 162 ? 43.167  34.625  -40.566 1.00 53.32  ? 156 SER H CB  1 
ATOM   1205 O OG  . SER A 1 162 ? 44.448  34.047  -40.750 1.00 62.73  ? 156 SER H OG  1 
ATOM   1206 N N   . GLY A 1 163 ? 39.905  34.581  -42.353 1.00 47.88  ? 157 GLY H N   1 
ATOM   1207 C CA  . GLY A 1 163 ? 38.516  34.950  -42.197 1.00 40.29  ? 157 GLY H CA  1 
ATOM   1208 C C   . GLY A 1 163 ? 38.212  36.424  -42.349 1.00 50.03  ? 157 GLY H C   1 
ATOM   1209 O O   . GLY A 1 163 ? 37.033  36.799  -42.323 1.00 49.31  ? 157 GLY H O   1 
ATOM   1210 N N   . ALA A 1 164 ? 39.231  37.272  -42.509 1.00 46.76  ? 158 ALA H N   1 
ATOM   1211 C CA  . ALA A 1 164 ? 38.995  38.704  -42.664 1.00 54.13  ? 158 ALA H CA  1 
ATOM   1212 C C   . ALA A 1 164 ? 38.446  39.045  -44.044 1.00 55.42  ? 158 ALA H C   1 
ATOM   1213 O O   . ALA A 1 164 ? 37.585  39.922  -44.172 1.00 54.64  ? 158 ALA H O   1 
ATOM   1214 C CB  . ALA A 1 164 ? 40.285  39.480  -42.403 1.00 47.22  ? 158 ALA H CB  1 
ATOM   1215 N N   . LEU A 1 165 ? 38.930  38.368  -45.084 1.00 48.58  ? 159 LEU H N   1 
ATOM   1216 C CA  . LEU A 1 165 ? 38.503  38.632  -46.454 1.00 47.19  ? 159 LEU H CA  1 
ATOM   1217 C C   . LEU A 1 165 ? 37.299  37.752  -46.770 1.00 50.57  ? 159 LEU H C   1 
ATOM   1218 O O   . LEU A 1 165 ? 37.426  36.529  -46.886 1.00 47.71  ? 159 LEU H O   1 
ATOM   1219 C CB  . LEU A 1 165 ? 39.647  38.377  -47.433 1.00 37.10  ? 159 LEU H CB  1 
ATOM   1220 C CG  . LEU A 1 165 ? 39.341  38.620  -48.912 1.00 28.06  ? 159 LEU H CG  1 
ATOM   1221 C CD1 . LEU A 1 165 ? 38.711  39.990  -49.108 1.00 32.70  ? 159 LEU H CD1 1 
ATOM   1222 C CD2 . LEU A 1 165 ? 40.607  38.489  -49.743 1.00 20.42  ? 159 LEU H CD2 1 
ATOM   1223 N N   . THR A 1 166 ? 36.129  38.374  -46.910 1.00 51.21  ? 160 THR H N   1 
ATOM   1224 C CA  . THR A 1 166 ? 34.896  37.656  -47.200 1.00 44.84  ? 160 THR H CA  1 
ATOM   1225 C C   . THR A 1 166 ? 34.191  38.125  -48.463 1.00 48.34  ? 160 THR H C   1 
ATOM   1226 O O   . THR A 1 166 ? 33.457  37.340  -49.067 1.00 44.82  ? 160 THR H O   1 
ATOM   1227 C CB  . THR A 1 166 ? 33.912  37.772  -46.025 1.00 45.21  ? 160 THR H CB  1 
ATOM   1228 O OG1 . THR A 1 166 ? 33.418  39.115  -45.945 1.00 56.63  ? 160 THR H OG1 1 
ATOM   1229 C CG2 . THR A 1 166 ? 34.593  37.410  -44.713 1.00 48.35  ? 160 THR H CG2 1 
ATOM   1230 N N   . SER A 1 167 ? 34.388  39.374  -48.878 1.00 54.11  ? 161 SER H N   1 
ATOM   1231 C CA  . SER A 1 167 ? 33.708  39.898  -50.054 1.00 56.08  ? 161 SER H CA  1 
ATOM   1232 C C   . SER A 1 167 ? 34.390  39.417  -51.327 1.00 48.97  ? 161 SER H C   1 
ATOM   1233 O O   . SER A 1 167 ? 35.620  39.419  -51.431 1.00 58.60  ? 161 SER H O   1 
ATOM   1234 C CB  . SER A 1 167 ? 33.682  41.426  -50.020 1.00 56.15  ? 161 SER H CB  1 
ATOM   1235 O OG  . SER A 1 167 ? 32.957  41.946  -51.121 1.00 48.18  ? 161 SER H OG  1 
ATOM   1236 N N   . GLY A 1 168 ? 33.580  39.004  -52.300 1.00 37.18  ? 162 GLY H N   1 
ATOM   1237 C CA  . GLY A 1 168 ? 34.090  38.490  -53.553 1.00 44.04  ? 162 GLY H CA  1 
ATOM   1238 C C   . GLY A 1 168 ? 34.580  37.060  -53.505 1.00 48.38  ? 162 GLY H C   1 
ATOM   1239 O O   . GLY A 1 168 ? 35.081  36.561  -54.521 1.00 42.90  ? 162 GLY H O   1 
ATOM   1240 N N   . VAL A 1 169 ? 34.453  36.387  -52.366 1.00 46.64  ? 163 VAL H N   1 
ATOM   1241 C CA  . VAL A 1 169 ? 34.921  35.014  -52.225 1.00 36.34  ? 163 VAL H CA  1 
ATOM   1242 C C   . VAL A 1 169 ? 33.877  34.069  -52.802 1.00 41.17  ? 163 VAL H C   1 
ATOM   1243 O O   . VAL A 1 169 ? 32.683  34.182  -52.499 1.00 34.97  ? 163 VAL H O   1 
ATOM   1244 C CB  . VAL A 1 169 ? 35.208  34.684  -50.751 1.00 32.48  ? 163 VAL H CB  1 
ATOM   1245 C CG1 . VAL A 1 169 ? 35.795  33.287  -50.627 1.00 38.02  ? 163 VAL H CG1 1 
ATOM   1246 C CG2 . VAL A 1 169 ? 36.140  35.719  -50.143 1.00 45.55  ? 163 VAL H CG2 1 
ATOM   1247 N N   . HIS A 1 170 ? 34.325  33.135  -53.638 1.00 41.84  ? 164 HIS H N   1 
ATOM   1248 C CA  . HIS A 1 170 ? 33.460  32.111  -54.222 1.00 29.66  ? 164 HIS H CA  1 
ATOM   1249 C C   . HIS A 1 170 ? 34.127  30.754  -54.017 1.00 32.60  ? 164 HIS H C   1 
ATOM   1250 O O   . HIS A 1 170 ? 35.005  30.363  -54.792 1.00 34.72  ? 164 HIS H O   1 
ATOM   1251 C CB  . HIS A 1 170 ? 33.198  32.384  -55.699 1.00 32.98  ? 164 HIS H CB  1 
ATOM   1252 C CG  . HIS A 1 170 ? 32.258  33.521  -55.947 1.00 30.90  ? 164 HIS H CG  1 
ATOM   1253 N ND1 . HIS A 1 170 ? 32.299  34.284  -57.094 1.00 35.33  ? 164 HIS H ND1 1 
ATOM   1254 C CD2 . HIS A 1 170 ? 31.244  34.020  -55.201 1.00 29.23  ? 164 HIS H CD2 1 
ATOM   1255 C CE1 . HIS A 1 170 ? 31.357  35.208  -57.041 1.00 44.20  ? 164 HIS H CE1 1 
ATOM   1256 N NE2 . HIS A 1 170 ? 30.702  35.069  -55.903 1.00 49.53  ? 164 HIS H NE2 1 
ATOM   1257 N N   . THR A 1 171 ? 33.715  30.043  -52.971 1.00 33.34  ? 165 THR H N   1 
ATOM   1258 C CA  . THR A 1 171 ? 34.179  28.683  -52.723 1.00 37.00  ? 165 THR H CA  1 
ATOM   1259 C C   . THR A 1 171 ? 33.231  27.725  -53.434 1.00 45.31  ? 165 THR H C   1 
ATOM   1260 O O   . THR A 1 171 ? 32.057  27.613  -53.066 1.00 36.70  ? 165 THR H O   1 
ATOM   1261 C CB  . THR A 1 171 ? 34.240  28.391  -51.226 1.00 34.90  ? 165 THR H CB  1 
ATOM   1262 O OG1 . THR A 1 171 ? 35.024  29.398  -50.573 1.00 42.85  ? 165 THR H OG1 1 
ATOM   1263 C CG2 . THR A 1 171 ? 34.871  27.029  -50.976 1.00 41.53  ? 165 THR H CG2 1 
ATOM   1264 N N   . PHE A 1 172 ? 33.735  27.045  -54.457 1.00 43.13  ? 166 PHE H N   1 
ATOM   1265 C CA  . PHE A 1 172 ? 32.891  26.175  -55.257 1.00 33.01  ? 166 PHE H CA  1 
ATOM   1266 C C   . PHE A 1 172 ? 32.606  24.865  -54.527 1.00 31.39  ? 166 PHE H C   1 
ATOM   1267 O O   . PHE A 1 172 ? 33.416  24.409  -53.715 1.00 35.59  ? 166 PHE H O   1 
ATOM   1268 C CB  . PHE A 1 172 ? 33.551  25.886  -56.600 1.00 31.01  ? 166 PHE H CB  1 
ATOM   1269 C CG  . PHE A 1 172 ? 33.610  27.077  -57.507 1.00 29.54  ? 166 PHE H CG  1 
ATOM   1270 C CD1 . PHE A 1 172 ? 32.551  27.373  -58.348 1.00 32.66  ? 166 PHE H CD1 1 
ATOM   1271 C CD2 . PHE A 1 172 ? 34.718  27.907  -57.514 1.00 32.51  ? 166 PHE H CD2 1 
ATOM   1272 C CE1 . PHE A 1 172 ? 32.596  28.471  -59.182 1.00 31.24  ? 166 PHE H CE1 1 
ATOM   1273 C CE2 . PHE A 1 172 ? 34.769  29.008  -58.347 1.00 38.00  ? 166 PHE H CE2 1 
ATOM   1274 C CZ  . PHE A 1 172 ? 33.705  29.289  -59.182 1.00 29.36  ? 166 PHE H CZ  1 
ATOM   1275 N N   . PRO A 1 173 ? 31.452  24.252  -54.791 1.00 34.74  ? 167 PRO H N   1 
ATOM   1276 C CA  . PRO A 1 173 ? 31.160  22.945  -54.192 1.00 29.02  ? 167 PRO H CA  1 
ATOM   1277 C C   . PRO A 1 173 ? 32.180  21.899  -54.613 1.00 27.90  ? 167 PRO H C   1 
ATOM   1278 O O   . PRO A 1 173 ? 32.677  21.903  -55.742 1.00 35.06  ? 167 PRO H O   1 
ATOM   1279 C CB  . PRO A 1 173 ? 29.762  22.615  -54.727 1.00 21.55  ? 167 PRO H CB  1 
ATOM   1280 C CG  . PRO A 1 173 ? 29.158  23.943  -55.041 1.00 20.42  ? 167 PRO H CG  1 
ATOM   1281 C CD  . PRO A 1 173 ? 30.294  24.800  -55.517 1.00 26.72  ? 167 PRO H CD  1 
ATOM   1282 N N   . ALA A 1 174 ? 32.491  20.998  -53.686 1.00 29.78  ? 168 ALA H N   1 
ATOM   1283 C CA  . ALA A 1 174 ? 33.422  19.918  -53.972 1.00 30.87  ? 168 ALA H CA  1 
ATOM   1284 C C   . ALA A 1 174 ? 32.845  18.979  -55.024 1.00 38.26  ? 168 ALA H C   1 
ATOM   1285 O O   . ALA A 1 174 ? 31.627  18.826  -55.155 1.00 37.02  ? 168 ALA H O   1 
ATOM   1286 C CB  . ALA A 1 174 ? 33.745  19.140  -52.697 1.00 29.67  ? 168 ALA H CB  1 
ATOM   1287 N N   . VAL A 1 175 ? 33.736  18.354  -55.787 1.00 45.15  ? 169 VAL H N   1 
ATOM   1288 C CA  . VAL A 1 175 ? 33.364  17.381  -56.806 1.00 35.92  ? 169 VAL H CA  1 
ATOM   1289 C C   . VAL A 1 175 ? 34.077  16.071  -56.503 1.00 39.22  ? 169 VAL H C   1 
ATOM   1290 O O   . VAL A 1 175 ? 35.256  16.063  -56.133 1.00 49.54  ? 169 VAL H O   1 
ATOM   1291 C CB  . VAL A 1 175 ? 33.695  17.881  -58.229 1.00 34.67  ? 169 VAL H CB  1 
ATOM   1292 C CG1 . VAL A 1 175 ? 32.827  19.081  -58.579 1.00 32.32  ? 169 VAL H CG1 1 
ATOM   1293 C CG2 . VAL A 1 175 ? 35.170  18.240  -58.349 1.00 63.54  ? 169 VAL H CG2 1 
ATOM   1294 N N   . LEU A 1 176 ? 33.350  14.965  -56.634 1.00 35.39  ? 170 LEU H N   1 
ATOM   1295 C CA  . LEU A 1 176 ? 33.893  13.641  -56.353 1.00 36.80  ? 170 LEU H CA  1 
ATOM   1296 C C   . LEU A 1 176 ? 34.575  13.117  -57.611 1.00 38.74  ? 170 LEU H C   1 
ATOM   1297 O O   . LEU A 1 176 ? 33.908  12.786  -58.597 1.00 46.26  ? 170 LEU H O   1 
ATOM   1298 C CB  . LEU A 1 176 ? 32.793  12.694  -55.880 1.00 30.19  ? 170 LEU H CB  1 
ATOM   1299 C CG  . LEU A 1 176 ? 33.229  11.273  -55.519 1.00 37.22  ? 170 LEU H CG  1 
ATOM   1300 C CD1 . LEU A 1 176 ? 34.464  11.297  -54.634 1.00 48.08  ? 170 LEU H CD1 1 
ATOM   1301 C CD2 . LEU A 1 176 ? 32.097  10.531  -54.830 1.00 40.41  ? 170 LEU H CD2 1 
ATOM   1302 N N   . GLN A 1 177 ? 35.902  13.047  -57.577 1.00 47.82  ? 171 GLN H N   1 
ATOM   1303 C CA  . GLN A 1 177 ? 36.658  12.543  -58.711 1.00 58.77  ? 171 GLN H CA  1 
ATOM   1304 C C   . GLN A 1 177 ? 36.512  11.027  -58.822 1.00 59.92  ? 171 GLN H C   1 
ATOM   1305 O O   . GLN A 1 177 ? 36.071  10.345  -57.892 1.00 54.70  ? 171 GLN H O   1 
ATOM   1306 C CB  . GLN A 1 177 ? 38.133  12.923  -58.582 1.00 57.03  ? 171 GLN H CB  1 
ATOM   1307 C CG  . GLN A 1 177 ? 38.385  14.421  -58.604 1.00 43.01  ? 171 GLN H CG  1 
ATOM   1308 C CD  . GLN A 1 177 ? 39.836  14.772  -58.343 1.00 69.00  ? 171 GLN H CD  1 
ATOM   1309 O OE1 . GLN A 1 177 ? 40.428  15.585  -59.054 1.00 73.13  ? 171 GLN H OE1 1 
ATOM   1310 N NE2 . GLN A 1 177 ? 40.416  14.165  -57.313 1.00 67.45  ? 171 GLN H NE2 1 
ATOM   1311 N N   . SER A 1 178 ? 36.894  10.502  -59.988 1.00 65.09  ? 172 SER H N   1 
ATOM   1312 C CA  . SER A 1 178 ? 36.824  9.064   -60.221 1.00 55.07  ? 172 SER H CA  1 
ATOM   1313 C C   . SER A 1 178 ? 37.776  8.283   -59.324 1.00 47.17  ? 172 SER H C   1 
ATOM   1314 O O   . SER A 1 178 ? 37.606  7.069   -59.168 1.00 56.91  ? 172 SER H O   1 
ATOM   1315 C CB  . SER A 1 178 ? 37.117  8.756   -61.690 1.00 61.02  ? 172 SER H CB  1 
ATOM   1316 O OG  . SER A 1 178 ? 36.166  9.375   -62.540 1.00 73.53  ? 172 SER H OG  1 
ATOM   1317 N N   . SER A 1 179 ? 38.765  8.948   -58.729 1.00 43.80  ? 173 SER H N   1 
ATOM   1318 C CA  . SER A 1 179 ? 39.682  8.310   -57.793 1.00 54.90  ? 173 SER H CA  1 
ATOM   1319 C C   . SER A 1 179 ? 39.055  8.065   -56.427 1.00 54.13  ? 173 SER H C   1 
ATOM   1320 O O   . SER A 1 179 ? 39.706  7.466   -55.564 1.00 54.83  ? 173 SER H O   1 
ATOM   1321 C CB  . SER A 1 179 ? 40.944  9.163   -57.632 1.00 63.61  ? 173 SER H CB  1 
ATOM   1322 O OG  . SER A 1 179 ? 40.631  10.447  -57.118 1.00 56.64  ? 173 SER H OG  1 
ATOM   1323 N N   . GLY A 1 180 ? 37.820  8.510   -56.211 1.00 46.59  ? 174 GLY H N   1 
ATOM   1324 C CA  . GLY A 1 180 ? 37.190  8.434   -54.912 1.00 50.22  ? 174 GLY H CA  1 
ATOM   1325 C C   . GLY A 1 180 ? 37.502  9.592   -53.992 1.00 55.96  ? 174 GLY H C   1 
ATOM   1326 O O   . GLY A 1 180 ? 36.965  9.638   -52.877 1.00 48.17  ? 174 GLY H O   1 
ATOM   1327 N N   . LEU A 1 181 ? 38.349  10.521  -54.420 1.00 53.37  ? 175 LEU H N   1 
ATOM   1328 C CA  . LEU A 1 181 ? 38.726  11.686  -53.636 1.00 48.42  ? 175 LEU H CA  1 
ATOM   1329 C C   . LEU A 1 181 ? 37.933  12.907  -54.090 1.00 50.76  ? 175 LEU H C   1 
ATOM   1330 O O   . LEU A 1 181 ? 37.294  12.912  -55.145 1.00 48.69  ? 175 LEU H O   1 
ATOM   1331 C CB  . LEU A 1 181 ? 40.230  11.947  -53.761 1.00 42.98  ? 175 LEU H CB  1 
ATOM   1332 C CG  . LEU A 1 181 ? 41.144  10.744  -53.524 1.00 41.72  ? 175 LEU H CG  1 
ATOM   1333 C CD1 . LEU A 1 181 ? 42.566  11.054  -53.965 1.00 56.53  ? 175 LEU H CD1 1 
ATOM   1334 C CD2 . LEU A 1 181 ? 41.112  10.327  -52.063 1.00 39.95  ? 175 LEU H CD2 1 
ATOM   1335 N N   . TYR A 1 182 ? 37.985  13.954  -53.274 1.00 44.03  ? 176 TYR H N   1 
ATOM   1336 C CA  . TYR A 1 182 ? 37.284  15.198  -53.552 1.00 41.26  ? 176 TYR H CA  1 
ATOM   1337 C C   . TYR A 1 182 ? 38.262  16.277  -53.997 1.00 44.55  ? 176 TYR H C   1 
ATOM   1338 O O   . TYR A 1 182 ? 39.432  16.285  -53.603 1.00 48.24  ? 176 TYR H O   1 
ATOM   1339 C CB  . TYR A 1 182 ? 36.506  15.678  -52.325 1.00 33.77  ? 176 TYR H CB  1 
ATOM   1340 C CG  . TYR A 1 182 ? 35.199  14.954  -52.112 1.00 38.62  ? 176 TYR H CG  1 
ATOM   1341 C CD1 . TYR A 1 182 ? 34.074  15.285  -52.856 1.00 30.92  ? 176 TYR H CD1 1 
ATOM   1342 C CD2 . TYR A 1 182 ? 35.086  13.943  -51.167 1.00 40.90  ? 176 TYR H CD2 1 
ATOM   1343 C CE1 . TYR A 1 182 ? 32.874  14.628  -52.666 1.00 36.49  ? 176 TYR H CE1 1 
ATOM   1344 C CE2 . TYR A 1 182 ? 33.889  13.281  -50.970 1.00 38.97  ? 176 TYR H CE2 1 
ATOM   1345 C CZ  . TYR A 1 182 ? 32.787  13.627  -51.722 1.00 33.07  ? 176 TYR H CZ  1 
ATOM   1346 O OH  . TYR A 1 182 ? 31.594  12.969  -51.528 1.00 33.43  ? 176 TYR H OH  1 
ATOM   1347 N N   . SER A 1 183 ? 37.767  17.187  -54.831 1.00 36.66  ? 177 SER H N   1 
ATOM   1348 C CA  . SER A 1 183 ? 38.543  18.323  -55.303 1.00 42.37  ? 177 SER H CA  1 
ATOM   1349 C C   . SER A 1 183 ? 37.689  19.577  -55.204 1.00 42.07  ? 177 SER H C   1 
ATOM   1350 O O   . SER A 1 183 ? 36.463  19.521  -55.336 1.00 38.98  ? 177 SER H O   1 
ATOM   1351 C CB  . SER A 1 183 ? 39.028  18.121  -56.743 1.00 46.43  ? 177 SER H CB  1 
ATOM   1352 O OG  . SER A 1 183 ? 39.783  19.235  -57.185 1.00 44.97  ? 177 SER H OG  1 
ATOM   1353 N N   . LEU A 1 184 ? 38.346  20.710  -54.975 1.00 39.57  ? 178 LEU H N   1 
ATOM   1354 C CA  . LEU A 1 184 ? 37.633  21.952  -54.718 1.00 37.66  ? 178 LEU H CA  1 
ATOM   1355 C C   . LEU A 1 184 ? 38.520  23.128  -55.098 1.00 44.08  ? 178 LEU H C   1 
ATOM   1356 O O   . LEU A 1 184 ? 39.749  23.047  -55.022 1.00 54.76  ? 178 LEU H O   1 
ATOM   1357 C CB  . LEU A 1 184 ? 37.209  22.040  -53.244 1.00 38.19  ? 178 LEU H CB  1 
ATOM   1358 C CG  . LEU A 1 184 ? 36.338  23.192  -52.735 1.00 26.09  ? 178 LEU H CG  1 
ATOM   1359 C CD1 . LEU A 1 184 ? 35.486  22.710  -51.574 1.00 38.08  ? 178 LEU H CD1 1 
ATOM   1360 C CD2 . LEU A 1 184 ? 37.182  24.381  -52.300 1.00 31.00  ? 178 LEU H CD2 1 
ATOM   1361 N N   . SER A 1 185 ? 37.879  24.220  -55.512 1.00 41.64  ? 179 SER H N   1 
ATOM   1362 C CA  . SER A 1 185 ? 38.555  25.481  -55.782 1.00 33.25  ? 179 SER H CA  1 
ATOM   1363 C C   . SER A 1 185 ? 37.782  26.619  -55.134 1.00 35.92  ? 179 SER H C   1 
ATOM   1364 O O   . SER A 1 185 ? 36.549  26.657  -55.190 1.00 44.58  ? 179 SER H O   1 
ATOM   1365 C CB  . SER A 1 185 ? 38.692  25.743  -57.288 1.00 29.80  ? 179 SER H CB  1 
ATOM   1366 O OG  . SER A 1 185 ? 39.761  25.001  -57.844 1.00 48.92  ? 179 SER H OG  1 
ATOM   1367 N N   . SER A 1 186 ? 38.514  27.538  -54.512 1.00 32.71  ? 180 SER H N   1 
ATOM   1368 C CA  . SER A 1 186 ? 37.954  28.765  -53.964 1.00 39.63  ? 180 SER H CA  1 
ATOM   1369 C C   . SER A 1 186 ? 38.700  29.944  -54.569 1.00 40.66  ? 180 SER H C   1 
ATOM   1370 O O   . SER A 1 186 ? 39.934  29.974  -54.548 1.00 37.11  ? 180 SER H O   1 
ATOM   1371 C CB  . SER A 1 186 ? 38.057  28.795  -52.437 1.00 35.45  ? 180 SER H CB  1 
ATOM   1372 O OG  . SER A 1 186 ? 37.465  29.969  -51.908 1.00 39.90  ? 180 SER H OG  1 
ATOM   1373 N N   . VAL A 1 187 ? 37.953  30.909  -55.106 1.00 35.04  ? 181 VAL H N   1 
ATOM   1374 C CA  . VAL A 1 187 ? 38.535  32.063  -55.774 1.00 40.78  ? 181 VAL H CA  1 
ATOM   1375 C C   . VAL A 1 187 ? 37.961  33.330  -55.157 1.00 33.14  ? 181 VAL H C   1 
ATOM   1376 O O   . VAL A 1 187 ? 36.874  33.332  -54.574 1.00 32.82  ? 181 VAL H O   1 
ATOM   1377 C CB  . VAL A 1 187 ? 38.286  32.048  -57.298 1.00 31.45  ? 181 VAL H CB  1 
ATOM   1378 C CG1 . VAL A 1 187 ? 38.899  30.804  -57.924 1.00 31.02  ? 181 VAL H CG1 1 
ATOM   1379 C CG2 . VAL A 1 187 ? 36.797  32.126  -57.594 1.00 29.93  ? 181 VAL H CG2 1 
ATOM   1380 N N   . VAL A 1 188 ? 38.716  34.421  -55.290 1.00 29.28  ? 182 VAL H N   1 
ATOM   1381 C CA  . VAL A 1 188 ? 38.335  35.705  -54.721 1.00 32.60  ? 182 VAL H CA  1 
ATOM   1382 C C   . VAL A 1 188 ? 38.536  36.790  -55.772 1.00 32.87  ? 182 VAL H C   1 
ATOM   1383 O O   . VAL A 1 188 ? 39.319  36.644  -56.714 1.00 30.16  ? 182 VAL H O   1 
ATOM   1384 C CB  . VAL A 1 188 ? 39.134  36.032  -53.438 1.00 38.67  ? 182 VAL H CB  1 
ATOM   1385 C CG1 . VAL A 1 188 ? 40.539  36.499  -53.781 1.00 40.47  ? 182 VAL H CG1 1 
ATOM   1386 C CG2 . VAL A 1 188 ? 38.402  37.064  -52.590 1.00 35.91  ? 182 VAL H CG2 1 
ATOM   1387 N N   . THR A 1 189 ? 37.804  37.887  -55.598 1.00 45.32  ? 183 THR H N   1 
ATOM   1388 C CA  . THR A 1 189 ? 37.854  39.036  -56.494 1.00 46.02  ? 183 THR H CA  1 
ATOM   1389 C C   . THR A 1 189 ? 38.375  40.237  -55.717 1.00 48.45  ? 183 THR H C   1 
ATOM   1390 O O   . THR A 1 189 ? 37.775  40.641  -54.714 1.00 55.68  ? 183 THR H O   1 
ATOM   1391 C CB  . THR A 1 189 ? 36.470  39.322  -57.086 1.00 47.56  ? 183 THR H CB  1 
ATOM   1392 O OG1 . THR A 1 189 ? 36.232  38.448  -58.198 1.00 36.29  ? 183 THR H OG1 1 
ATOM   1393 C CG2 . THR A 1 189 ? 36.362  40.763  -57.543 1.00 53.98  ? 183 THR H CG2 1 
ATOM   1394 N N   . VAL A 1 190 ? 39.495  40.793  -56.170 1.00 49.58  ? 184 VAL H N   1 
ATOM   1395 C CA  . VAL A 1 190 ? 40.134  41.932  -55.513 1.00 46.77  ? 184 VAL H CA  1 
ATOM   1396 C C   . VAL A 1 190 ? 40.546  42.945  -56.571 1.00 55.77  ? 184 VAL H C   1 
ATOM   1397 O O   . VAL A 1 190 ? 40.698  42.605  -57.752 1.00 52.35  ? 184 VAL H O   1 
ATOM   1398 C CB  . VAL A 1 190 ? 41.365  41.505  -54.685 1.00 42.00  ? 184 VAL H CB  1 
ATOM   1399 C CG1 . VAL A 1 190 ? 40.982  40.464  -53.639 1.00 42.97  ? 184 VAL H CG1 1 
ATOM   1400 C CG2 . VAL A 1 190 ? 42.469  40.986  -55.594 1.00 36.77  ? 184 VAL H CG2 1 
ATOM   1401 N N   . PRO A 1 191 ? 40.710  44.210  -56.178 1.00 67.25  ? 185 PRO H N   1 
ATOM   1402 C CA  . PRO A 1 191 ? 41.229  45.203  -57.127 1.00 63.81  ? 185 PRO H CA  1 
ATOM   1403 C C   . PRO A 1 191 ? 42.618  44.822  -57.616 1.00 67.61  ? 185 PRO H C   1 
ATOM   1404 O O   . PRO A 1 191 ? 43.453  44.331  -56.854 1.00 68.04  ? 185 PRO H O   1 
ATOM   1405 C CB  . PRO A 1 191 ? 41.251  46.502  -56.311 1.00 62.88  ? 185 PRO H CB  1 
ATOM   1406 C CG  . PRO A 1 191 ? 41.218  46.063  -54.879 1.00 53.83  ? 185 PRO H CG  1 
ATOM   1407 C CD  . PRO A 1 191 ? 40.388  44.819  -54.875 1.00 56.81  ? 185 PRO H CD  1 
ATOM   1408 N N   . SER A 1 192 ? 42.863  45.058  -58.907 1.00 66.28  ? 186 SER H N   1 
ATOM   1409 C CA  . SER A 1 192 ? 44.138  44.688  -59.509 1.00 73.44  ? 186 SER H CA  1 
ATOM   1410 C C   . SER A 1 192 ? 45.289  45.569  -59.045 1.00 74.00  ? 186 SER H C   1 
ATOM   1411 O O   . SER A 1 192 ? 46.448  45.233  -59.310 1.00 77.34  ? 186 SER H O   1 
ATOM   1412 C CB  . SER A 1 192 ? 44.034  44.737  -61.035 1.00 71.94  ? 186 SER H CB  1 
ATOM   1413 O OG  . SER A 1 192 ? 43.751  46.049  -61.486 1.00 86.93  ? 186 SER H OG  1 
ATOM   1414 N N   . SER A 1 193 ? 45.002  46.681  -58.366 1.00 78.27  ? 187 SER H N   1 
ATOM   1415 C CA  . SER A 1 193 ? 46.052  47.570  -57.890 1.00 69.85  ? 187 SER H CA  1 
ATOM   1416 C C   . SER A 1 193 ? 46.698  47.083  -56.600 1.00 78.91  ? 187 SER H C   1 
ATOM   1417 O O   . SER A 1 193 ? 47.787  47.554  -56.252 1.00 88.04  ? 187 SER H O   1 
ATOM   1418 C CB  . SER A 1 193 ? 45.488  48.976  -57.675 1.00 56.61  ? 187 SER H CB  1 
ATOM   1419 O OG  . SER A 1 193 ? 44.692  49.381  -58.775 1.00 86.65  ? 187 SER H OG  1 
ATOM   1420 N N   . SER A 1 194 ? 46.062  46.152  -55.892 1.00 80.82  ? 188 SER H N   1 
ATOM   1421 C CA  . SER A 1 194 ? 46.513  45.713  -54.578 1.00 75.66  ? 188 SER H CA  1 
ATOM   1422 C C   . SER A 1 194 ? 47.290  44.403  -54.618 1.00 76.06  ? 188 SER H C   1 
ATOM   1423 O O   . SER A 1 194 ? 47.535  43.811  -53.562 1.00 76.80  ? 188 SER H O   1 
ATOM   1424 C CB  . SER A 1 194 ? 45.315  45.576  -53.635 1.00 61.93  ? 188 SER H CB  1 
ATOM   1425 O OG  . SER A 1 194 ? 45.706  45.022  -52.392 1.00 69.82  ? 188 SER H OG  1 
ATOM   1426 N N   . LEU A 1 195 ? 47.676  43.933  -55.807 1.00 64.46  ? 189 LEU H N   1 
ATOM   1427 C CA  . LEU A 1 195 ? 48.367  42.650  -55.904 1.00 73.22  ? 189 LEU H CA  1 
ATOM   1428 C C   . LEU A 1 195 ? 49.717  42.686  -55.196 1.00 80.80  ? 189 LEU H C   1 
ATOM   1429 O O   . LEU A 1 195 ? 50.076  41.744  -54.480 1.00 62.18  ? 189 LEU H O   1 
ATOM   1430 C CB  . LEU A 1 195 ? 48.541  42.256  -57.371 1.00 76.07  ? 189 LEU H CB  1 
ATOM   1431 C CG  . LEU A 1 195 ? 47.261  41.993  -58.168 1.00 56.25  ? 189 LEU H CG  1 
ATOM   1432 C CD1 . LEU A 1 195 ? 47.594  41.527  -59.579 1.00 38.68  ? 189 LEU H CD1 1 
ATOM   1433 C CD2 . LEU A 1 195 ? 46.380  40.977  -57.457 1.00 46.67  ? 189 LEU H CD2 1 
ATOM   1434 N N   . GLY A 1 196 ? 50.478  43.762  -55.381 1.00 78.35  ? 190 GLY H N   1 
ATOM   1435 C CA  . GLY A 1 196 ? 51.795  43.860  -54.782 1.00 74.88  ? 190 GLY H CA  1 
ATOM   1436 C C   . GLY A 1 196 ? 51.799  44.394  -53.364 1.00 87.61  ? 190 GLY H C   1 
ATOM   1437 O O   . GLY A 1 196 ? 52.636  43.996  -52.548 1.00 93.08  ? 190 GLY H O   1 
ATOM   1438 N N   . THR A 1 197 ? 50.867  45.299  -53.056 1.00 85.89  ? 191 THR H N   1 
ATOM   1439 C CA  . THR A 1 197 ? 50.861  45.932  -51.740 1.00 80.17  ? 191 THR H CA  1 
ATOM   1440 C C   . THR A 1 197 ? 50.373  44.973  -50.661 1.00 74.81  ? 191 THR H C   1 
ATOM   1441 O O   . THR A 1 197 ? 50.946  44.918  -49.566 1.00 78.27  ? 191 THR H O   1 
ATOM   1442 C CB  . THR A 1 197 ? 49.990  47.188  -51.763 1.00 71.87  ? 191 THR H CB  1 
ATOM   1443 O OG1 . THR A 1 197 ? 48.608  46.814  -51.685 1.00 65.64  ? 191 THR H OG1 1 
ATOM   1444 C CG2 . THR A 1 197 ? 50.223  47.972  -53.046 1.00 73.29  ? 191 THR H CG2 1 
ATOM   1445 N N   . GLN A 1 198 ? 49.322  44.212  -50.948 1.00 74.71  ? 192 GLN H N   1 
ATOM   1446 C CA  . GLN A 1 198 ? 48.693  43.336  -49.974 1.00 74.27  ? 192 GLN H CA  1 
ATOM   1447 C C   . GLN A 1 198 ? 48.975  41.879  -50.317 1.00 76.42  ? 192 GLN H C   1 
ATOM   1448 O O   . GLN A 1 198 ? 49.158  41.521  -51.485 1.00 69.39  ? 192 GLN H O   1 
ATOM   1449 C CB  . GLN A 1 198 ? 47.181  43.585  -49.917 1.00 63.34  ? 192 GLN H CB  1 
ATOM   1450 C CG  . GLN A 1 198 ? 46.466  42.914  -48.755 1.00 65.75  ? 192 GLN H CG  1 
ATOM   1451 C CD  . GLN A 1 198 ? 45.055  43.435  -48.565 1.00 76.00  ? 192 GLN H CD  1 
ATOM   1452 O OE1 . GLN A 1 198 ? 44.706  44.509  -49.057 1.00 71.52  ? 192 GLN H OE1 1 
ATOM   1453 N NE2 . GLN A 1 198 ? 44.233  42.676  -47.849 1.00 73.18  ? 192 GLN H NE2 1 
ATOM   1454 N N   . THR A 1 199 ? 49.018  41.044  -49.284 1.00 74.33  ? 193 THR H N   1 
ATOM   1455 C CA  . THR A 1 199 ? 49.261  39.616  -49.426 1.00 65.98  ? 193 THR H CA  1 
ATOM   1456 C C   . THR A 1 199 ? 47.978  38.851  -49.134 1.00 66.50  ? 193 THR H C   1 
ATOM   1457 O O   . THR A 1 199 ? 47.333  39.081  -48.105 1.00 71.41  ? 193 THR H O   1 
ATOM   1458 C CB  . THR A 1 199 ? 50.378  39.155  -48.486 1.00 64.98  ? 193 THR H CB  1 
ATOM   1459 O OG1 . THR A 1 199 ? 50.122  39.643  -47.163 1.00 73.58  ? 193 THR H OG1 1 
ATOM   1460 C CG2 . THR A 1 199 ? 51.723  39.680  -48.964 1.00 73.97  ? 193 THR H CG2 1 
ATOM   1461 N N   . TYR A 1 200 ? 47.611  37.950  -50.039 1.00 54.62  ? 194 TYR H N   1 
ATOM   1462 C CA  . TYR A 1 200 ? 46.419  37.126  -49.898 1.00 49.24  ? 194 TYR H CA  1 
ATOM   1463 C C   . TYR A 1 200 ? 46.830  35.690  -49.609 1.00 42.11  ? 194 TYR H C   1 
ATOM   1464 O O   . TYR A 1 200 ? 47.630  35.108  -50.349 1.00 37.78  ? 194 TYR H O   1 
ATOM   1465 C CB  . TYR A 1 200 ? 45.557  37.186  -51.160 1.00 43.76  ? 194 TYR H CB  1 
ATOM   1466 C CG  . TYR A 1 200 ? 45.065  38.573  -51.502 1.00 42.63  ? 194 TYR H CG  1 
ATOM   1467 C CD1 . TYR A 1 200 ? 43.993  39.135  -50.822 1.00 48.37  ? 194 TYR H CD1 1 
ATOM   1468 C CD2 . TYR A 1 200 ? 45.667  39.317  -52.508 1.00 46.35  ? 194 TYR H CD2 1 
ATOM   1469 C CE1 . TYR A 1 200 ? 43.537  40.402  -51.131 1.00 46.29  ? 194 TYR H CE1 1 
ATOM   1470 C CE2 . TYR A 1 200 ? 45.218  40.585  -52.825 1.00 52.90  ? 194 TYR H CE2 1 
ATOM   1471 C CZ  . TYR A 1 200 ? 44.152  41.122  -52.132 1.00 55.11  ? 194 TYR H CZ  1 
ATOM   1472 O OH  . TYR A 1 200 ? 43.699  42.384  -52.441 1.00 53.31  ? 194 TYR H OH  1 
ATOM   1473 N N   . ILE A 1 201 ? 46.287  35.128  -48.532 1.00 44.72  ? 195 ILE H N   1 
ATOM   1474 C CA  . ILE A 1 201 ? 46.584  33.764  -48.114 1.00 50.04  ? 195 ILE H CA  1 
ATOM   1475 C C   . ILE A 1 201 ? 45.270  33.032  -47.888 1.00 53.31  ? 195 ILE H C   1 
ATOM   1476 O O   . ILE A 1 201 ? 44.384  33.540  -47.192 1.00 52.37  ? 195 ILE H O   1 
ATOM   1477 C CB  . ILE A 1 201 ? 47.448  33.731  -46.838 1.00 48.23  ? 195 ILE H CB  1 
ATOM   1478 C CG1 . ILE A 1 201 ? 48.699  34.594  -47.019 1.00 49.67  ? 195 ILE H CG1 1 
ATOM   1479 C CG2 . ILE A 1 201 ? 47.821  32.299  -46.481 1.00 62.67  ? 195 ILE H CG2 1 
ATOM   1480 C CD1 . ILE A 1 201 ? 49.823  34.261  -46.061 1.00 55.86  ? 195 ILE H CD1 1 
ATOM   1481 N N   . CYS A 1 202 ? 45.144  31.845  -48.474 1.00 54.83  ? 196 CYS H N   1 
ATOM   1482 C CA  . CYS A 1 202 ? 43.977  30.998  -48.281 1.00 57.64  ? 196 CYS H CA  1 
ATOM   1483 C C   . CYS A 1 202 ? 44.286  29.964  -47.207 1.00 55.17  ? 196 CYS H C   1 
ATOM   1484 O O   . CYS A 1 202 ? 45.365  29.363  -47.206 1.00 52.63  ? 196 CYS H O   1 
ATOM   1485 C CB  . CYS A 1 202 ? 43.570  30.313  -49.588 1.00 43.86  ? 196 CYS H CB  1 
ATOM   1486 S SG  . CYS A 1 202 ? 44.716  29.041  -50.158 1.00 74.39  ? 196 CYS H SG  1 
ATOM   1487 N N   . ASN A 1 203 ? 43.347  29.774  -46.288 1.00 51.76  ? 197 ASN H N   1 
ATOM   1488 C CA  . ASN A 1 203 ? 43.517  28.863  -45.165 1.00 47.65  ? 197 ASN H CA  1 
ATOM   1489 C C   . ASN A 1 203 ? 42.620  27.655  -45.387 1.00 54.77  ? 197 ASN H C   1 
ATOM   1490 O O   . ASN A 1 203 ? 41.392  27.785  -45.402 1.00 47.60  ? 197 ASN H O   1 
ATOM   1491 C CB  . ASN A 1 203 ? 43.182  29.559  -43.849 1.00 54.77  ? 197 ASN H CB  1 
ATOM   1492 C CG  . ASN A 1 203 ? 43.507  31.037  -43.880 1.00 57.91  ? 197 ASN H CG  1 
ATOM   1493 O OD1 . ASN A 1 203 ? 42.620  31.878  -43.756 1.00 54.62  ? 197 ASN H OD1 1 
ATOM   1494 N ND2 . ASN A 1 203 ? 44.783  31.362  -44.060 1.00 58.41  ? 197 ASN H ND2 1 
ATOM   1495 N N   . VAL A 1 204 ? 43.231  26.488  -45.559 1.00 48.46  ? 198 VAL H N   1 
ATOM   1496 C CA  . VAL A 1 204 ? 42.512  25.253  -45.839 1.00 36.46  ? 198 VAL H CA  1 
ATOM   1497 C C   . VAL A 1 204 ? 42.639  24.352  -44.620 1.00 38.75  ? 198 VAL H C   1 
ATOM   1498 O O   . VAL A 1 204 ? 43.754  24.044  -44.180 1.00 48.53  ? 198 VAL H O   1 
ATOM   1499 C CB  . VAL A 1 204 ? 43.048  24.560  -47.100 1.00 45.72  ? 198 VAL H CB  1 
ATOM   1500 C CG1 . VAL A 1 204 ? 42.029  23.563  -47.630 1.00 44.04  ? 198 VAL H CG1 1 
ATOM   1501 C CG2 . VAL A 1 204 ? 43.402  25.594  -48.159 1.00 49.20  ? 198 VAL H CG2 1 
ATOM   1502 N N   . ASN A 1 205 ? 41.502  23.934  -44.073 1.00 52.33  ? 199 ASN H N   1 
ATOM   1503 C CA  . ASN A 1 205 ? 41.465  23.068  -42.902 1.00 55.18  ? 199 ASN H CA  1 
ATOM   1504 C C   . ASN A 1 205 ? 40.651  21.827  -43.236 1.00 53.06  ? 199 ASN H C   1 
ATOM   1505 O O   . ASN A 1 205 ? 39.496  21.933  -43.661 1.00 45.70  ? 199 ASN H O   1 
ATOM   1506 C CB  . ASN A 1 205 ? 40.869  23.798  -41.695 1.00 53.84  ? 199 ASN H CB  1 
ATOM   1507 C CG  . ASN A 1 205 ? 40.968  22.988  -40.417 1.00 60.68  ? 199 ASN H CG  1 
ATOM   1508 O OD1 . ASN A 1 205 ? 41.690  21.992  -40.354 1.00 66.42  ? 199 ASN H OD1 1 
ATOM   1509 N ND2 . ASN A 1 205 ? 40.247  23.416  -39.387 1.00 54.22  ? 199 ASN H ND2 1 
ATOM   1510 N N   . HIS A 1 206 ? 41.257  20.658  -43.047 1.00 56.02  ? 200 HIS H N   1 
ATOM   1511 C CA  . HIS A 1 206 ? 40.592  19.370  -43.225 1.00 47.08  ? 200 HIS H CA  1 
ATOM   1512 C C   . HIS A 1 206 ? 40.604  18.684  -41.863 1.00 56.37  ? 200 HIS H C   1 
ATOM   1513 O O   . HIS A 1 206 ? 41.533  17.941  -41.536 1.00 54.04  ? 200 HIS H O   1 
ATOM   1514 C CB  . HIS A 1 206 ? 41.281  18.530  -44.296 1.00 37.41  ? 200 HIS H CB  1 
ATOM   1515 C CG  . HIS A 1 206 ? 40.549  17.270  -44.642 1.00 52.40  ? 200 HIS H CG  1 
ATOM   1516 N ND1 . HIS A 1 206 ? 40.832  16.059  -44.050 1.00 63.68  ? 200 HIS H ND1 1 
ATOM   1517 C CD2 . HIS A 1 206 ? 39.548  17.033  -45.522 1.00 51.34  ? 200 HIS H CD2 1 
ATOM   1518 C CE1 . HIS A 1 206 ? 40.037  15.129  -44.550 1.00 51.13  ? 200 HIS H CE1 1 
ATOM   1519 N NE2 . HIS A 1 206 ? 39.248  15.694  -45.445 1.00 52.28  ? 200 HIS H NE2 1 
ATOM   1520 N N   . LYS A 1 207 ? 39.567  18.954  -41.069 1.00 57.47  ? 201 LYS H N   1 
ATOM   1521 C CA  . LYS A 1 207 ? 39.486  18.385  -39.726 1.00 57.76  ? 201 LYS H CA  1 
ATOM   1522 C C   . LYS A 1 207 ? 39.559  16.861  -39.689 1.00 54.84  ? 201 LYS H C   1 
ATOM   1523 O O   . LYS A 1 207 ? 40.235  16.333  -38.788 1.00 58.24  ? 201 LYS H O   1 
ATOM   1524 C CB  . LYS A 1 207 ? 38.211  18.885  -39.032 1.00 56.17  ? 201 LYS H CB  1 
ATOM   1525 C CG  . LYS A 1 207 ? 38.228  20.372  -38.708 1.00 66.92  ? 201 LYS H CG  1 
ATOM   1526 C CD  . LYS A 1 207 ? 37.035  20.774  -37.853 1.00 70.31  ? 201 LYS H CD  1 
ATOM   1527 C CE  . LYS A 1 207 ? 37.137  22.229  -37.416 1.00 74.12  ? 201 LYS H CE  1 
ATOM   1528 N NZ  . LYS A 1 207 ? 36.056  22.602  -36.462 1.00 58.25  ? 201 LYS H NZ  1 
ATOM   1529 N N   . PRO A 1 208 ? 38.911  16.102  -40.583 1.00 50.99  ? 202 PRO H N   1 
ATOM   1530 C CA  . PRO A 1 208 ? 39.002  14.634  -40.494 1.00 52.49  ? 202 PRO H CA  1 
ATOM   1531 C C   . PRO A 1 208 ? 40.412  14.074  -40.632 1.00 48.13  ? 202 PRO H C   1 
ATOM   1532 O O   . PRO A 1 208 ? 40.587  12.863  -40.438 1.00 46.50  ? 202 PRO H O   1 
ATOM   1533 C CB  . PRO A 1 208 ? 38.108  14.154  -41.647 1.00 50.21  ? 202 PRO H CB  1 
ATOM   1534 C CG  . PRO A 1 208 ? 37.147  15.253  -41.852 1.00 43.90  ? 202 PRO H CG  1 
ATOM   1535 C CD  . PRO A 1 208 ? 37.916  16.513  -41.592 1.00 46.28  ? 202 PRO H CD  1 
ATOM   1536 N N   . SER A 1 209 ? 41.420  14.897  -40.956 1.00 43.49  ? 203 SER H N   1 
ATOM   1537 C CA  . SER A 1 209 ? 42.765  14.365  -41.145 1.00 52.79  ? 203 SER H CA  1 
ATOM   1538 C C   . SER A 1 209 ? 43.874  15.242  -40.563 1.00 67.63  ? 203 SER H C   1 
ATOM   1539 O O   . SER A 1 209 ? 45.041  15.049  -40.928 1.00 91.89  ? 203 SER H O   1 
ATOM   1540 C CB  . SER A 1 209 ? 43.051  14.144  -42.634 1.00 63.59  ? 203 SER H CB  1 
ATOM   1541 O OG  . SER A 1 209 ? 43.062  15.374  -43.342 1.00 63.80  ? 203 SER H OG  1 
ATOM   1542 N N   . ASN A 1 210 ? 43.557  16.209  -39.697 1.00 60.68  ? 204 ASN H N   1 
ATOM   1543 C CA  . ASN A 1 210 ? 44.519  17.123  -39.077 1.00 69.79  ? 204 ASN H CA  1 
ATOM   1544 C C   . ASN A 1 210 ? 45.135  18.074  -40.106 1.00 70.69  ? 204 ASN H C   1 
ATOM   1545 O O   . ASN A 1 210 ? 45.843  19.006  -39.718 1.00 72.06  ? 204 ASN H O   1 
ATOM   1546 C CB  . ASN A 1 210 ? 45.613  16.341  -38.311 1.00 76.08  ? 204 ASN H CB  1 
ATOM   1547 C CG  . ASN A 1 210 ? 46.708  17.222  -37.642 1.00 87.60  ? 204 ASN H CG  1 
ATOM   1548 O OD1 . ASN A 1 210 ? 47.728  16.683  -37.209 1.00 91.48  ? 204 ASN H OD1 1 
ATOM   1549 N ND2 . ASN A 1 210 ? 46.493  18.534  -37.537 1.00 86.71  ? 204 ASN H ND2 1 
ATOM   1550 N N   . THR A 1 211 ? 44.832  17.919  -41.396 1.00 56.83  ? 205 THR H N   1 
ATOM   1551 C CA  . THR A 1 211 ? 45.494  18.731  -42.409 1.00 48.19  ? 205 THR H CA  1 
ATOM   1552 C C   . THR A 1 211 ? 45.098  20.197  -42.258 1.00 50.56  ? 205 THR H C   1 
ATOM   1553 O O   . THR A 1 211 ? 43.910  20.538  -42.240 1.00 58.06  ? 205 THR H O   1 
ATOM   1554 C CB  . THR A 1 211 ? 45.162  18.227  -43.811 1.00 61.72  ? 205 THR H CB  1 
ATOM   1555 O OG1 . THR A 1 211 ? 45.335  16.806  -43.853 1.00 64.52  ? 205 THR H OG1 1 
ATOM   1556 C CG2 . THR A 1 211 ? 46.125  18.857  -44.809 1.00 52.52  ? 205 THR H CG2 1 
ATOM   1557 N N   . LYS A 1 212 ? 46.104  21.054  -42.098 1.00 51.50  ? 206 LYS H N   1 
ATOM   1558 C CA  . LYS A 1 212 ? 45.905  22.496  -41.989 1.00 49.73  ? 206 LYS H CA  1 
ATOM   1559 C C   . LYS A 1 212 ? 46.955  23.173  -42.860 1.00 42.48  ? 206 LYS H C   1 
ATOM   1560 O O   . LYS A 1 212 ? 48.149  23.133  -42.544 1.00 56.10  ? 206 LYS H O   1 
ATOM   1561 C CB  . LYS A 1 212 ? 46.003  22.970  -40.536 1.00 52.31  ? 206 LYS H CB  1 
ATOM   1562 C CG  . LYS A 1 212 ? 44.944  23.993  -40.140 1.00 53.20  ? 206 LYS H CG  1 
ATOM   1563 C CD  . LYS A 1 212 ? 44.962  24.263  -38.640 1.00 69.95  ? 206 LYS H CD  1 
ATOM   1564 C CE  . LYS A 1 212 ? 43.813  25.169  -38.223 1.00 80.20  ? 206 LYS H CE  1 
ATOM   1565 N NZ  . LYS A 1 212 ? 43.794  25.406  -36.752 1.00 68.48  ? 206 LYS H NZ  1 
ATOM   1566 N N   . VAL A 1 213 ? 46.512  23.796  -43.949 1.00 41.31  ? 207 VAL H N   1 
ATOM   1567 C CA  . VAL A 1 213 ? 47.402  24.362  -44.957 1.00 44.29  ? 207 VAL H CA  1 
ATOM   1568 C C   . VAL A 1 213 ? 47.130  25.853  -45.076 1.00 44.78  ? 207 VAL H C   1 
ATOM   1569 O O   . VAL A 1 213 ? 45.977  26.271  -45.234 1.00 46.86  ? 207 VAL H O   1 
ATOM   1570 C CB  . VAL A 1 213 ? 47.225  23.673  -46.322 1.00 36.45  ? 207 VAL H CB  1 
ATOM   1571 C CG1 . VAL A 1 213 ? 48.324  24.111  -47.283 1.00 35.29  ? 207 VAL H CG1 1 
ATOM   1572 C CG2 . VAL A 1 213 ? 47.213  22.163  -46.161 1.00 41.45  ? 207 VAL H CG2 1 
ATOM   1573 N N   . ASP A 1 214 ? 48.193  26.649  -45.000 1.00 50.84  ? 208 ASP H N   1 
ATOM   1574 C CA  . ASP A 1 214 ? 48.149  28.086  -45.253 1.00 55.32  ? 208 ASP H CA  1 
ATOM   1575 C C   . ASP A 1 214 ? 48.970  28.349  -46.508 1.00 53.20  ? 208 ASP H C   1 
ATOM   1576 O O   . ASP A 1 214 ? 50.204  28.310  -46.468 1.00 51.76  ? 208 ASP H O   1 
ATOM   1577 C CB  . ASP A 1 214 ? 48.686  28.867  -44.058 1.00 67.04  ? 208 ASP H CB  1 
ATOM   1578 C CG  . ASP A 1 214 ? 47.769  28.797  -42.854 1.00 73.41  ? 208 ASP H CG  1 
ATOM   1579 O OD1 . ASP A 1 214 ? 46.708  29.457  -42.880 1.00 75.38  ? 208 ASP H OD1 1 
ATOM   1580 O OD2 . ASP A 1 214 ? 48.104  28.078  -41.888 1.00 81.39  ? 208 ASP H OD2 1 
ATOM   1581 N N   . LYS A 1 215 ? 48.288  28.606  -47.620 1.00 53.06  ? 209 LYS H N   1 
ATOM   1582 C CA  . LYS A 1 215 ? 48.931  28.776  -48.916 1.00 54.30  ? 209 LYS H CA  1 
ATOM   1583 C C   . LYS A 1 215 ? 48.942  30.252  -49.287 1.00 58.97  ? 209 LYS H C   1 
ATOM   1584 O O   . LYS A 1 215 ? 47.884  30.887  -49.363 1.00 53.37  ? 209 LYS H O   1 
ATOM   1585 C CB  . LYS A 1 215 ? 48.215  27.959  -49.993 1.00 54.47  ? 209 LYS H CB  1 
ATOM   1586 C CG  . LYS A 1 215 ? 48.826  28.094  -51.380 1.00 54.92  ? 209 LYS H CG  1 
ATOM   1587 C CD  . LYS A 1 215 ? 50.265  27.609  -51.394 1.00 56.43  ? 209 LYS H CD  1 
ATOM   1588 C CE  . LYS A 1 215 ? 50.352  26.144  -50.995 1.00 58.12  ? 209 LYS H CE  1 
ATOM   1589 N NZ  . LYS A 1 215 ? 51.762  25.679  -50.888 1.00 52.24  ? 209 LYS H NZ  1 
ATOM   1590 N N   . LYS A 1 216 ? 50.135  30.788  -49.527 1.00 57.60  ? 210 LYS H N   1 
ATOM   1591 C CA  . LYS A 1 216 ? 50.289  32.158  -49.994 1.00 50.65  ? 210 LYS H CA  1 
ATOM   1592 C C   . LYS A 1 216 ? 50.237  32.177  -51.515 1.00 55.54  ? 210 LYS H C   1 
ATOM   1593 O O   . LYS A 1 216 ? 50.995  31.461  -52.178 1.00 63.32  ? 210 LYS H O   1 
ATOM   1594 C CB  . LYS A 1 216 ? 51.609  32.753  -49.504 1.00 63.24  ? 210 LYS H CB  1 
ATOM   1595 C CG  . LYS A 1 216 ? 51.587  34.262  -49.327 1.00 84.93  ? 210 LYS H CG  1 
ATOM   1596 C CD  . LYS A 1 216 ? 52.991  34.816  -49.131 1.00 98.95  ? 210 LYS H CD  1 
ATOM   1597 C CE  . LYS A 1 216 ? 52.954  36.269  -48.684 1.00 85.60  ? 210 LYS H CE  1 
ATOM   1598 N NZ  . LYS A 1 216 ? 54.318  36.837  -48.509 1.00 78.45  ? 210 LYS H NZ  1 
ATOM   1599 N N   . VAL A 1 217 ? 49.339  32.989  -52.067 1.00 52.48  ? 211 VAL H N   1 
ATOM   1600 C CA  . VAL A 1 217 ? 49.145  33.077  -53.510 1.00 66.40  ? 211 VAL H CA  1 
ATOM   1601 C C   . VAL A 1 217 ? 49.540  34.477  -53.962 1.00 59.59  ? 211 VAL H C   1 
ATOM   1602 O O   . VAL A 1 217 ? 48.976  35.474  -53.491 1.00 42.00  ? 211 VAL H O   1 
ATOM   1603 C CB  . VAL A 1 217 ? 47.700  32.740  -53.916 1.00 60.70  ? 211 VAL H CB  1 
ATOM   1604 C CG1 . VAL A 1 217 ? 46.698  33.472  -53.030 1.00 55.57  ? 211 VAL H CG1 1 
ATOM   1605 C CG2 . VAL A 1 217 ? 47.470  33.059  -55.385 1.00 50.29  ? 211 VAL H CG2 1 
ATOM   1606 N N   . GLU A 1 218 ? 50.509  34.548  -54.867 1.00 58.92  ? 212 GLU H N   1 
ATOM   1607 C CA  . GLU A 1 218 ? 51.077  35.797  -55.347 1.00 48.96  ? 212 GLU H CA  1 
ATOM   1608 C C   . GLU A 1 218 ? 51.333  35.682  -56.841 1.00 49.02  ? 212 GLU H C   1 
ATOM   1609 O O   . GLU A 1 218 ? 51.536  34.573  -57.351 1.00 50.13  ? 212 GLU H O   1 
ATOM   1610 C CB  . GLU A 1 218 ? 52.385  36.126  -54.611 1.00 62.51  ? 212 GLU H CB  1 
ATOM   1611 C CG  . GLU A 1 218 ? 53.378  34.977  -54.591 1.00 65.84  ? 212 GLU H CG  1 
ATOM   1612 C CD  . GLU A 1 218 ? 54.418  35.121  -53.499 1.00 76.98  ? 212 GLU H CD  1 
ATOM   1613 O OE1 . GLU A 1 218 ? 54.685  36.264  -53.072 1.00 81.11  ? 212 GLU H OE1 1 
ATOM   1614 O OE2 . GLU A 1 218 ? 54.964  34.086  -53.061 1.00 82.29  ? 212 GLU H OE2 1 
ATOM   1615 N N   . PRO A 1 219 ? 51.326  36.801  -57.567 1.00 59.50  ? 213 PRO H N   1 
ATOM   1616 C CA  . PRO A 1 219 ? 51.562  36.738  -59.015 1.00 63.21  ? 213 PRO H CA  1 
ATOM   1617 C C   . PRO A 1 219 ? 52.934  36.161  -59.334 1.00 73.44  ? 213 PRO H C   1 
ATOM   1618 O O   . PRO A 1 219 ? 53.909  36.388  -58.614 1.00 79.50  ? 213 PRO H O   1 
ATOM   1619 C CB  . PRO A 1 219 ? 51.447  38.202  -59.459 1.00 57.07  ? 213 PRO H CB  1 
ATOM   1620 C CG  . PRO A 1 219 ? 51.657  39.003  -58.213 1.00 40.26  ? 213 PRO H CG  1 
ATOM   1621 C CD  . PRO A 1 219 ? 51.073  38.178  -57.111 1.00 43.10  ? 213 PRO H CD  1 
ATOM   1622 N N   . LYS A 1 220 ? 52.998  35.405  -60.426 1.00 61.01  ? 214 LYS H N   1 
ATOM   1623 C CA  . LYS A 1 220 ? 54.228  34.725  -60.811 1.00 76.15  ? 214 LYS H CA  1 
ATOM   1624 C C   . LYS A 1 220 ? 54.943  35.464  -61.938 1.00 69.48  ? 214 LYS H C   1 
ATOM   1625 O O   . LYS A 1 220 ? 54.866  36.688  -62.038 1.00 82.17  ? 214 LYS H O   1 
ATOM   1626 C CB  . LYS A 1 220 ? 53.932  33.286  -61.233 1.00 78.34  ? 214 LYS H CB  1 
ATOM   1627 C CG  . LYS A 1 220 ? 55.074  32.324  -60.966 1.00 80.56  ? 214 LYS H CG  1 
ATOM   1628 C CD  . LYS A 1 220 ? 55.232  32.061  -59.478 1.00 80.52  ? 214 LYS H CD  1 
ATOM   1629 C CE  . LYS A 1 220 ? 56.554  31.374  -59.188 1.00 80.00  ? 214 LYS H CE  1 
ATOM   1630 N NZ  . LYS A 1 220 ? 56.444  30.403  -58.065 1.00 58.05  ? 214 LYS H NZ  1 
ATOM   1631 N N   . ASP B 2 1   ? 0.462   3.553   -54.547 1.00 55.86  ? 1   ASP L N   1 
ATOM   1632 C CA  . ASP B 2 1   ? 1.038   4.791   -54.038 1.00 52.15  ? 1   ASP L CA  1 
ATOM   1633 C C   . ASP B 2 1   ? 0.561   5.986   -54.856 1.00 56.19  ? 1   ASP L C   1 
ATOM   1634 O O   . ASP B 2 1   ? 0.345   5.876   -56.063 1.00 58.26  ? 1   ASP L O   1 
ATOM   1635 C CB  . ASP B 2 1   ? 2.566   4.720   -54.055 1.00 41.89  ? 1   ASP L CB  1 
ATOM   1636 C CG  . ASP B 2 1   ? 3.097   3.449   -53.421 1.00 74.58  ? 1   ASP L CG  1 
ATOM   1637 O OD1 . ASP B 2 1   ? 2.281   2.639   -52.932 1.00 69.10  ? 1   ASP L OD1 1 
ATOM   1638 O OD2 . ASP B 2 1   ? 4.332   3.256   -53.418 1.00 80.74  ? 1   ASP L OD2 1 
ATOM   1639 N N   . ILE B 2 2   ? 0.397   7.125   -54.193 1.00 49.03  ? 2   ILE L N   1 
ATOM   1640 C CA  . ILE B 2 2   ? -0.031  8.356   -54.847 1.00 44.90  ? 2   ILE L CA  1 
ATOM   1641 C C   . ILE B 2 2   ? 1.196   9.083   -55.374 1.00 44.10  ? 2   ILE L C   1 
ATOM   1642 O O   . ILE B 2 2   ? 2.171   9.290   -54.642 1.00 47.88  ? 2   ILE L O   1 
ATOM   1643 C CB  . ILE B 2 2   ? -0.828  9.245   -53.878 1.00 36.18  ? 2   ILE L CB  1 
ATOM   1644 C CG1 . ILE B 2 2   ? -2.092  8.521   -53.414 1.00 35.36  ? 2   ILE L CG1 1 
ATOM   1645 C CG2 . ILE B 2 2   ? -1.178  10.572  -54.536 1.00 27.86  ? 2   ILE L CG2 1 
ATOM   1646 C CD1 . ILE B 2 2   ? -2.943  9.333   -52.470 1.00 38.99  ? 2   ILE L CD1 1 
ATOM   1647 N N   . GLN B 2 3   ? 1.153   9.468   -56.646 1.00 37.32  ? 3   GLN L N   1 
ATOM   1648 C CA  . GLN B 2 3   ? 2.263   10.141  -57.306 1.00 34.75  ? 3   GLN L CA  1 
ATOM   1649 C C   . GLN B 2 3   ? 1.938   11.617  -57.478 1.00 45.14  ? 3   GLN L C   1 
ATOM   1650 O O   . GLN B 2 3   ? 0.826   11.971  -57.887 1.00 60.47  ? 3   GLN L O   1 
ATOM   1651 C CB  . GLN B 2 3   ? 2.560   9.500   -58.663 1.00 36.96  ? 3   GLN L CB  1 
ATOM   1652 C CG  . GLN B 2 3   ? 2.834   8.010   -58.588 1.00 48.92  ? 3   GLN L CG  1 
ATOM   1653 C CD  . GLN B 2 3   ? 3.980   7.675   -57.653 1.00 79.73  ? 3   GLN L CD  1 
ATOM   1654 O OE1 . GLN B 2 3   ? 4.988   8.381   -57.608 1.00 89.99  ? 3   GLN L OE1 1 
ATOM   1655 N NE2 . GLN B 2 3   ? 3.827   6.595   -56.894 1.00 75.52  ? 3   GLN L NE2 1 
ATOM   1656 N N   . LEU B 2 4   ? 2.906   12.471  -57.160 1.00 47.99  ? 4   LEU L N   1 
ATOM   1657 C CA  . LEU B 2 4   ? 2.772   13.914  -57.291 1.00 37.87  ? 4   LEU L CA  1 
ATOM   1658 C C   . LEU B 2 4   ? 3.823   14.420  -58.267 1.00 35.52  ? 4   LEU L C   1 
ATOM   1659 O O   . LEU B 2 4   ? 4.999   14.056  -58.159 1.00 40.58  ? 4   LEU L O   1 
ATOM   1660 C CB  . LEU B 2 4   ? 2.932   14.609  -55.938 1.00 40.40  ? 4   LEU L CB  1 
ATOM   1661 C CG  . LEU B 2 4   ? 2.177   14.007  -54.753 1.00 39.63  ? 4   LEU L CG  1 
ATOM   1662 C CD1 . LEU B 2 4   ? 2.519   14.762  -53.486 1.00 29.14  ? 4   LEU L CD1 1 
ATOM   1663 C CD2 . LEU B 2 4   ? 0.677   14.018  -54.996 1.00 53.94  ? 4   LEU L CD2 1 
ATOM   1664 N N   . THR B 2 5   ? 3.402   15.253  -59.213 1.00 47.24  ? 5   THR L N   1 
ATOM   1665 C CA  . THR B 2 5   ? 4.303   15.857  -60.182 1.00 51.30  ? 5   THR L CA  1 
ATOM   1666 C C   . THR B 2 5   ? 4.159   17.372  -60.131 1.00 48.73  ? 5   THR L C   1 
ATOM   1667 O O   . THR B 2 5   ? 3.051   17.897  -59.976 1.00 45.39  ? 5   THR L O   1 
ATOM   1668 C CB  . THR B 2 5   ? 4.033   15.334  -61.604 1.00 42.10  ? 5   THR L CB  1 
ATOM   1669 O OG1 . THR B 2 5   ? 4.937   15.955  -62.527 1.00 48.82  ? 5   THR L OG1 1 
ATOM   1670 C CG2 . THR B 2 5   ? 2.596   15.615  -62.031 1.00 42.03  ? 5   THR L CG2 1 
ATOM   1671 N N   . GLN B 2 6   ? 5.285   18.069  -60.239 1.00 51.04  ? 6   GLN L N   1 
ATOM   1672 C CA  . GLN B 2 6   ? 5.319   19.521  -60.165 1.00 37.39  ? 6   GLN L CA  1 
ATOM   1673 C C   . GLN B 2 6   ? 5.713   20.114  -61.511 1.00 41.61  ? 6   GLN L C   1 
ATOM   1674 O O   . GLN B 2 6   ? 6.248   19.431  -62.389 1.00 39.81  ? 6   GLN L O   1 
ATOM   1675 C CB  . GLN B 2 6   ? 6.296   20.001  -59.087 1.00 34.51  ? 6   GLN L CB  1 
ATOM   1676 C CG  . GLN B 2 6   ? 5.920   19.602  -57.676 1.00 50.14  ? 6   GLN L CG  1 
ATOM   1677 C CD  . GLN B 2 6   ? 6.841   20.216  -56.639 1.00 42.94  ? 6   GLN L CD  1 
ATOM   1678 O OE1 . GLN B 2 6   ? 6.997   19.686  -55.538 1.00 38.78  ? 6   GLN L OE1 1 
ATOM   1679 N NE2 . GLN B 2 6   ? 7.454   21.342  -56.986 1.00 35.32  ? 6   GLN L NE2 1 
ATOM   1680 N N   . SER B 2 7   ? 5.432   21.410  -61.659 1.00 40.00  ? 7   SER L N   1 
ATOM   1681 C CA  . SER B 2 7   ? 5.801   22.153  -62.852 1.00 44.41  ? 7   SER L CA  1 
ATOM   1682 C C   . SER B 2 7   ? 5.858   23.626  -62.492 1.00 44.39  ? 7   SER L C   1 
ATOM   1683 O O   . SER B 2 7   ? 4.969   24.105  -61.775 1.00 42.55  ? 7   SER L O   1 
ATOM   1684 C CB  . SER B 2 7   ? 4.803   21.925  -63.992 1.00 48.00  ? 7   SER L CB  1 
ATOM   1685 O OG  . SER B 2 7   ? 3.532   22.464  -63.672 1.00 61.29  ? 7   SER L OG  1 
ATOM   1686 N N   . PRO B 2 8   ? 6.871   24.367  -62.950 1.00 32.85  ? 8   PRO L N   1 
ATOM   1687 C CA  . PRO B 2 8   ? 8.037   23.916  -63.721 1.00 42.67  ? 8   PRO L CA  1 
ATOM   1688 C C   . PRO B 2 8   ? 9.116   23.311  -62.829 1.00 43.83  ? 8   PRO L C   1 
ATOM   1689 O O   . PRO B 2 8   ? 9.019   23.372  -61.608 1.00 45.67  ? 8   PRO L O   1 
ATOM   1690 C CB  . PRO B 2 8   ? 8.509   25.206  -64.401 1.00 51.84  ? 8   PRO L CB  1 
ATOM   1691 C CG  . PRO B 2 8   ? 8.164   26.277  -63.407 1.00 44.32  ? 8   PRO L CG  1 
ATOM   1692 C CD  . PRO B 2 8   ? 6.858   25.833  -62.789 1.00 33.07  ? 8   PRO L CD  1 
ATOM   1693 N N   . ASP B 2 9   ? 10.147  22.698  -63.416 1.00 52.52  ? 9   ASP L N   1 
ATOM   1694 C CA  . ASP B 2 9   ? 11.276  22.231  -62.618 1.00 52.17  ? 9   ASP L CA  1 
ATOM   1695 C C   . ASP B 2 9   ? 12.034  23.403  -62.007 1.00 58.73  ? 9   ASP L C   1 
ATOM   1696 O O   . ASP B 2 9   ? 12.468  23.337  -60.851 1.00 49.18  ? 9   ASP L O   1 
ATOM   1697 C CB  . ASP B 2 9   ? 12.209  21.381  -63.477 1.00 46.09  ? 9   ASP L CB  1 
ATOM   1698 C CG  . ASP B 2 9   ? 11.457  20.428  -64.380 1.00 72.45  ? 9   ASP L CG  1 
ATOM   1699 O OD1 . ASP B 2 9   ? 10.624  20.905  -65.180 1.00 97.28  ? 9   ASP L OD1 1 
ATOM   1700 O OD2 . ASP B 2 9   ? 11.700  19.207  -64.295 1.00 72.16  ? 9   ASP L OD2 1 
ATOM   1701 N N   . SER B 2 10  ? 12.204  24.480  -62.770 1.00 60.02  ? 10  SER L N   1 
ATOM   1702 C CA  . SER B 2 10  ? 12.858  25.693  -62.301 1.00 48.82  ? 10  SER L CA  1 
ATOM   1703 C C   . SER B 2 10  ? 11.989  26.893  -62.643 1.00 49.37  ? 10  SER L C   1 
ATOM   1704 O O   . SER B 2 10  ? 11.379  26.944  -63.716 1.00 54.73  ? 10  SER L O   1 
ATOM   1705 C CB  . SER B 2 10  ? 14.251  25.858  -62.923 1.00 44.66  ? 10  SER L CB  1 
ATOM   1706 O OG  . SER B 2 10  ? 15.108  24.793  -62.549 1.00 61.12  ? 10  SER L OG  1 
ATOM   1707 N N   . LEU B 2 11  ? 11.934  27.854  -61.725 1.00 40.21  ? 11  LEU L N   1 
ATOM   1708 C CA  . LEU B 2 11  ? 11.128  29.055  -61.887 1.00 41.01  ? 11  LEU L CA  1 
ATOM   1709 C C   . LEU B 2 11  ? 11.985  30.281  -61.612 1.00 48.26  ? 11  LEU L C   1 
ATOM   1710 O O   . LEU B 2 11  ? 12.757  30.307  -60.648 1.00 52.79  ? 11  LEU L O   1 
ATOM   1711 C CB  . LEU B 2 11  ? 9.916   29.035  -60.948 1.00 47.04  ? 11  LEU L CB  1 
ATOM   1712 C CG  . LEU B 2 11  ? 8.903   30.174  -61.065 1.00 41.29  ? 11  LEU L CG  1 
ATOM   1713 C CD1 . LEU B 2 11  ? 8.184   30.128  -62.403 1.00 37.23  ? 11  LEU L CD1 1 
ATOM   1714 C CD2 . LEU B 2 11  ? 7.909   30.109  -59.918 1.00 47.55  ? 11  LEU L CD2 1 
ATOM   1715 N N   . ALA B 2 12  ? 11.840  31.299  -62.459 1.00 45.69  ? 12  ALA L N   1 
ATOM   1716 C CA  . ALA B 2 12  ? 12.600  32.541  -62.341 1.00 43.21  ? 12  ALA L CA  1 
ATOM   1717 C C   . ALA B 2 12  ? 11.631  33.713  -62.404 1.00 49.68  ? 12  ALA L C   1 
ATOM   1718 O O   . ALA B 2 12  ? 11.133  34.052  -63.484 1.00 63.19  ? 12  ALA L O   1 
ATOM   1719 C CB  . ALA B 2 12  ? 13.653  32.652  -63.445 1.00 47.97  ? 12  ALA L CB  1 
ATOM   1720 N N   . VAL B 2 13  ? 11.363  34.329  -61.257 1.00 41.32  ? 13  VAL L N   1 
ATOM   1721 C CA  . VAL B 2 13  ? 10.523  35.517  -61.198 1.00 52.99  ? 13  VAL L CA  1 
ATOM   1722 C C   . VAL B 2 13  ? 11.330  36.640  -60.563 1.00 51.49  ? 13  VAL L C   1 
ATOM   1723 O O   . VAL B 2 13  ? 12.217  36.408  -59.735 1.00 46.98  ? 13  VAL L O   1 
ATOM   1724 C CB  . VAL B 2 13  ? 9.202   35.271  -60.429 1.00 54.59  ? 13  VAL L CB  1 
ATOM   1725 C CG1 . VAL B 2 13  ? 8.582   33.943  -60.842 1.00 57.88  ? 13  VAL L CG1 1 
ATOM   1726 C CG2 . VAL B 2 13  ? 9.425   35.314  -58.934 1.00 41.79  ? 13  VAL L CG2 1 
ATOM   1727 N N   . SER B 2 14  ? 11.029  37.867  -60.980 1.00 55.89  ? 14  SER L N   1 
ATOM   1728 C CA  . SER B 2 14  ? 11.776  39.027  -60.526 1.00 52.89  ? 14  SER L CA  1 
ATOM   1729 C C   . SER B 2 14  ? 11.398  39.391  -59.093 1.00 58.27  ? 14  SER L C   1 
ATOM   1730 O O   . SER B 2 14  ? 10.388  38.935  -58.549 1.00 59.67  ? 14  SER L O   1 
ATOM   1731 C CB  . SER B 2 14  ? 11.535  40.220  -61.453 1.00 31.88  ? 14  SER L CB  1 
ATOM   1732 O OG  . SER B 2 14  ? 12.285  41.350  -61.040 1.00 63.93  ? 14  SER L OG  1 
ATOM   1733 N N   . LEU B 2 15  ? 12.242  40.222  -58.483 1.00 46.37  ? 15  LEU L N   1 
ATOM   1734 C CA  . LEU B 2 15  ? 11.995  40.692  -57.128 1.00 49.09  ? 15  LEU L CA  1 
ATOM   1735 C C   . LEU B 2 15  ? 10.672  41.445  -57.071 1.00 58.65  ? 15  LEU L C   1 
ATOM   1736 O O   . LEU B 2 15  ? 10.416  42.335  -57.887 1.00 64.35  ? 15  LEU L O   1 
ATOM   1737 C CB  . LEU B 2 15  ? 13.148  41.592  -56.673 1.00 40.29  ? 15  LEU L CB  1 
ATOM   1738 C CG  . LEU B 2 15  ? 13.683  41.378  -55.257 1.00 46.10  ? 15  LEU L CG  1 
ATOM   1739 C CD1 . LEU B 2 15  ? 13.840  39.891  -55.014 1.00 52.85  ? 15  LEU L CD1 1 
ATOM   1740 C CD2 . LEU B 2 15  ? 15.013  42.076  -55.067 1.00 53.89  ? 15  LEU L CD2 1 
ATOM   1741 N N   . GLY B 2 16  ? 9.826   41.081  -56.107 1.00 53.17  ? 16  GLY L N   1 
ATOM   1742 C CA  . GLY B 2 16  ? 8.518   41.688  -55.968 1.00 50.80  ? 16  GLY L CA  1 
ATOM   1743 C C   . GLY B 2 16  ? 7.436   41.117  -56.859 1.00 55.43  ? 16  GLY L C   1 
ATOM   1744 O O   . GLY B 2 16  ? 6.263   41.477  -56.687 1.00 47.29  ? 16  GLY L O   1 
ATOM   1745 N N   . GLU B 2 17  ? 7.778   40.241  -57.802 1.00 52.04  ? 17  GLU L N   1 
ATOM   1746 C CA  . GLU B 2 17  ? 6.794   39.647  -58.692 1.00 49.73  ? 17  GLU L CA  1 
ATOM   1747 C C   . GLU B 2 17  ? 6.196   38.388  -58.066 1.00 58.13  ? 17  GLU L C   1 
ATOM   1748 O O   . GLU B 2 17  ? 6.530   37.995  -56.945 1.00 54.52  ? 17  GLU L O   1 
ATOM   1749 C CB  . GLU B 2 17  ? 7.417   39.339  -60.053 1.00 60.57  ? 17  GLU L CB  1 
ATOM   1750 C CG  . GLU B 2 17  ? 7.433   40.517  -61.012 1.00 61.24  ? 17  GLU L CG  1 
ATOM   1751 C CD  . GLU B 2 17  ? 7.938   40.138  -62.393 1.00 82.28  ? 17  GLU L CD  1 
ATOM   1752 O OE1 . GLU B 2 17  ? 8.122   38.929  -62.650 1.00 80.43  ? 17  GLU L OE1 1 
ATOM   1753 O OE2 . GLU B 2 17  ? 8.150   41.050  -63.221 1.00 78.10  ? 17  GLU L OE2 1 
ATOM   1754 N N   . ARG B 2 18  ? 5.304   37.742  -58.812 1.00 56.19  ? 18  ARG L N   1 
ATOM   1755 C CA  . ARG B 2 18  ? 4.563   36.582  -58.340 1.00 56.69  ? 18  ARG L CA  1 
ATOM   1756 C C   . ARG B 2 18  ? 5.192   35.297  -58.864 1.00 51.27  ? 18  ARG L C   1 
ATOM   1757 O O   . ARG B 2 18  ? 5.562   35.208  -60.039 1.00 49.45  ? 18  ARG L O   1 
ATOM   1758 C CB  . ARG B 2 18  ? 3.098   36.658  -58.781 1.00 56.88  ? 18  ARG L CB  1 
ATOM   1759 C CG  . ARG B 2 18  ? 2.251   35.484  -58.320 1.00 59.60  ? 18  ARG L CG  1 
ATOM   1760 C CD  . ARG B 2 18  ? 0.899   35.442  -59.021 1.00 59.81  ? 18  ARG L CD  1 
ATOM   1761 N NE  . ARG B 2 18  ? 1.024   35.232  -60.459 1.00 67.81  ? 18  ARG L NE  1 
ATOM   1762 C CZ  . ARG B 2 18  ? 0.617   36.093  -61.382 1.00 65.28  ? 18  ARG L CZ  1 
ATOM   1763 N NH1 . ARG B 2 18  ? 0.028   37.232  -61.054 1.00 58.88  ? 18  ARG L NH1 1 
ATOM   1764 N NH2 . ARG B 2 18  ? 0.797   35.800  -62.667 1.00 59.01  ? 18  ARG L NH2 1 
ATOM   1765 N N   . ALA B 2 19  ? 5.310   34.306  -57.984 1.00 43.87  ? 19  ALA L N   1 
ATOM   1766 C CA  . ALA B 2 19  ? 5.826   32.988  -58.331 1.00 46.20  ? 19  ALA L CA  1 
ATOM   1767 C C   . ALA B 2 19  ? 4.712   31.964  -58.156 1.00 50.05  ? 19  ALA L C   1 
ATOM   1768 O O   . ALA B 2 19  ? 4.128   31.858  -57.072 1.00 45.79  ? 19  ALA L O   1 
ATOM   1769 C CB  . ALA B 2 19  ? 7.033   32.628  -57.465 1.00 39.87  ? 19  ALA L CB  1 
ATOM   1770 N N   . THR B 2 20  ? 4.424   31.212  -59.216 1.00 51.10  ? 20  THR L N   1 
ATOM   1771 C CA  . THR B 2 20  ? 3.366   30.210  -59.209 1.00 44.54  ? 20  THR L CA  1 
ATOM   1772 C C   . THR B 2 20  ? 3.967   28.841  -59.490 1.00 33.93  ? 20  THR L C   1 
ATOM   1773 O O   . THR B 2 20  ? 4.668   28.660  -60.491 1.00 37.78  ? 20  THR L O   1 
ATOM   1774 C CB  . THR B 2 20  ? 2.287   30.534  -60.246 1.00 32.24  ? 20  THR L CB  1 
ATOM   1775 O OG1 . THR B 2 20  ? 1.852   31.888  -60.078 1.00 39.00  ? 20  THR L OG1 1 
ATOM   1776 C CG2 . THR B 2 20  ? 1.094   29.605  -60.079 1.00 42.63  ? 20  THR L CG2 1 
ATOM   1777 N N   . ILE B 2 21  ? 3.687   27.882  -58.610 1.00 33.51  ? 21  ILE L N   1 
ATOM   1778 C CA  . ILE B 2 21  ? 4.200   26.522  -58.723 1.00 39.56  ? 21  ILE L CA  1 
ATOM   1779 C C   . ILE B 2 21  ? 3.020   25.562  -58.681 1.00 40.29  ? 21  ILE L C   1 
ATOM   1780 O O   . ILE B 2 21  ? 2.195   25.626  -57.763 1.00 35.47  ? 21  ILE L O   1 
ATOM   1781 C CB  . ILE B 2 21  ? 5.205   26.199  -57.601 1.00 27.95  ? 21  ILE L CB  1 
ATOM   1782 C CG1 . ILE B 2 21  ? 6.360   27.204  -57.621 1.00 25.03  ? 21  ILE L CG1 1 
ATOM   1783 C CG2 . ILE B 2 21  ? 5.720   24.774  -57.742 1.00 29.34  ? 21  ILE L CG2 1 
ATOM   1784 C CD1 . ILE B 2 21  ? 7.170   27.233  -56.345 1.00 32.76  ? 21  ILE L CD1 1 
ATOM   1785 N N   . ASN B 2 22  ? 2.942   24.673  -59.668 1.00 43.53  ? 22  ASN L N   1 
ATOM   1786 C CA  . ASN B 2 22  ? 1.828   23.746  -59.802 1.00 43.24  ? 22  ASN L CA  1 
ATOM   1787 C C   . ASN B 2 22  ? 2.203   22.376  -59.252 1.00 41.22  ? 22  ASN L C   1 
ATOM   1788 O O   . ASN B 2 22  ? 3.343   21.927  -59.396 1.00 41.97  ? 22  ASN L O   1 
ATOM   1789 C CB  . ASN B 2 22  ? 1.399   23.616  -61.265 1.00 44.12  ? 22  ASN L CB  1 
ATOM   1790 C CG  . ASN B 2 22  ? 0.943   24.933  -61.859 1.00 51.79  ? 22  ASN L CG  1 
ATOM   1791 O OD1 . ASN B 2 22  ? -0.187  25.367  -61.639 1.00 58.13  ? 22  ASN L OD1 1 
ATOM   1792 N ND2 . ASN B 2 22  ? 1.820   25.573  -62.624 1.00 59.48  ? 22  ASN L ND2 1 
ATOM   1793 N N   . CYS B 2 23  ? 1.234   21.721  -58.617 1.00 33.95  ? 23  CYS L N   1 
ATOM   1794 C CA  . CYS B 2 23  ? 1.384   20.363  -58.112 1.00 37.53  ? 23  CYS L CA  1 
ATOM   1795 C C   . CYS B 2 23  ? 0.169   19.559  -58.548 1.00 48.51  ? 23  CYS L C   1 
ATOM   1796 O O   . CYS B 2 23  ? -0.969  19.974  -58.305 1.00 45.39  ? 23  CYS L O   1 
ATOM   1797 C CB  . CYS B 2 23  ? 1.520   20.355  -56.585 1.00 38.32  ? 23  CYS L CB  1 
ATOM   1798 S SG  . CYS B 2 23  ? 1.773   18.733  -55.819 1.00 58.93  ? 23  CYS L SG  1 
ATOM   1799 N N   . LYS B 2 24  ? 0.406   18.418  -59.192 1.00 51.64  ? 24  LYS L N   1 
ATOM   1800 C CA  . LYS B 2 24  ? -0.658  17.583  -59.732 1.00 36.90  ? 24  LYS L CA  1 
ATOM   1801 C C   . LYS B 2 24  ? -0.569  16.191  -59.126 1.00 45.50  ? 24  LYS L C   1 
ATOM   1802 O O   . LYS B 2 24  ? 0.514   15.597  -59.080 1.00 53.44  ? 24  LYS L O   1 
ATOM   1803 C CB  . LYS B 2 24  ? -0.576  17.507  -61.256 1.00 42.93  ? 24  LYS L CB  1 
ATOM   1804 C CG  . LYS B 2 24  ? -1.782  16.877  -61.922 1.00 51.02  ? 24  LYS L CG  1 
ATOM   1805 C CD  . LYS B 2 24  ? -2.239  17.756  -63.067 1.00 82.23  ? 24  LYS L CD  1 
ATOM   1806 C CE  . LYS B 2 24  ? -2.912  16.962  -64.166 1.00 66.75  ? 24  LYS L CE  1 
ATOM   1807 N NZ  . LYS B 2 24  ? -2.830  17.720  -65.444 1.00 69.84  ? 24  LYS L NZ  1 
ATOM   1808 N N   . SER B 2 25  ? -1.707  15.676  -58.671 1.00 40.83  ? 25  SER L N   1 
ATOM   1809 C CA  . SER B 2 25  ? -1.783  14.407  -57.965 1.00 38.91  ? 25  SER L CA  1 
ATOM   1810 C C   . SER B 2 25  ? -2.370  13.332  -58.870 1.00 43.78  ? 25  SER L C   1 
ATOM   1811 O O   . SER B 2 25  ? -3.251  13.608  -59.692 1.00 48.05  ? 25  SER L O   1 
ATOM   1812 C CB  . SER B 2 25  ? -2.630  14.546  -56.697 1.00 30.72  ? 25  SER L CB  1 
ATOM   1813 O OG  . SER B 2 25  ? -2.588  13.365  -55.916 1.00 51.15  ? 25  SER L OG  1 
ATOM   1814 N N   . SER B 2 26  ? -1.871  12.102  -58.717 1.00 33.96  ? 26  SER L N   1 
ATOM   1815 C CA  . SER B 2 26  ? -2.386  10.988  -59.508 1.00 38.39  ? 26  SER L CA  1 
ATOM   1816 C C   . SER B 2 26  ? -3.846  10.703  -59.177 1.00 42.40  ? 26  SER L C   1 
ATOM   1817 O O   . SER B 2 26  ? -4.652  10.430  -60.074 1.00 49.58  ? 26  SER L O   1 
ATOM   1818 C CB  . SER B 2 26  ? -1.528  9.742   -59.284 1.00 26.51  ? 26  SER L CB  1 
ATOM   1819 O OG  . SER B 2 26  ? -1.525  9.358   -57.921 1.00 32.35  ? 26  SER L OG  1 
ATOM   1820 N N   . GLN B 2 27  ? -4.204  10.755  -57.897 1.00 43.17  ? 27  GLN L N   1 
ATOM   1821 C CA  . GLN B 2 27  ? -5.578  10.577  -57.454 1.00 40.05  ? 27  GLN L CA  1 
ATOM   1822 C C   . GLN B 2 27  ? -5.936  11.701  -56.491 1.00 40.18  ? 27  GLN L C   1 
ATOM   1823 O O   . GLN B 2 27  ? -5.072  12.445  -56.020 1.00 49.06  ? 27  GLN L O   1 
ATOM   1824 C CB  . GLN B 2 27  ? -5.786  9.210   -56.787 1.00 39.89  ? 27  GLN L CB  1 
ATOM   1825 C CG  . GLN B 2 27  ? -5.168  9.090   -55.406 1.00 34.65  ? 27  GLN L CG  1 
ATOM   1826 C CD  . GLN B 2 27  ? -5.219  7.673   -54.867 1.00 43.46  ? 27  GLN L CD  1 
ATOM   1827 O OE1 . GLN B 2 27  ? -4.617  6.760   -55.433 1.00 40.50  ? 27  GLN L OE1 1 
ATOM   1828 N NE2 . GLN B 2 27  ? -5.941  7.482   -53.768 1.00 47.12  ? 27  GLN L NE2 1 
ATOM   1829 N N   . SER B 2 28  A -7.229  11.826  -56.210 1.00 35.03  ? 27  SER L N   1 
ATOM   1830 C CA  . SER B 2 28  A -7.697  12.882  -55.325 1.00 35.22  ? 27  SER L CA  1 
ATOM   1831 C C   . SER B 2 28  A -7.190  12.662  -53.906 1.00 46.17  ? 27  SER L C   1 
ATOM   1832 O O   . SER B 2 28  A -7.225  11.546  -53.378 1.00 50.90  ? 27  SER L O   1 
ATOM   1833 C CB  . SER B 2 28  A -9.223  12.946  -55.330 1.00 41.19  ? 27  SER L CB  1 
ATOM   1834 O OG  . SER B 2 28  A -9.694  13.905  -54.399 1.00 43.63  ? 27  SER L OG  1 
ATOM   1835 N N   . VAL B 2 29  B -6.711  13.742  -53.289 1.00 43.20  ? 27  VAL L N   1 
ATOM   1836 C CA  . VAL B 2 29  B -6.306  13.723  -51.891 1.00 37.71  ? 27  VAL L CA  1 
ATOM   1837 C C   . VAL B 2 29  B -7.344  14.390  -50.996 1.00 50.92  ? 27  VAL L C   1 
ATOM   1838 O O   . VAL B 2 29  B -7.063  14.672  -49.828 1.00 52.07  ? 27  VAL L O   1 
ATOM   1839 C CB  . VAL B 2 29  B -4.923  14.368  -51.704 1.00 35.10  ? 27  VAL L CB  1 
ATOM   1840 C CG1 . VAL B 2 29  B -3.876  13.606  -52.501 1.00 35.22  ? 27  VAL L CG1 1 
ATOM   1841 C CG2 . VAL B 2 29  B -4.959  15.826  -52.120 1.00 36.55  ? 27  VAL L CG2 1 
ATOM   1842 N N   . LEU B 2 30  C -8.536  14.655  -51.523 1.00 49.88  ? 27  LEU L N   1 
ATOM   1843 C CA  . LEU B 2 30  C -9.615  15.220  -50.730 1.00 34.84  ? 27  LEU L CA  1 
ATOM   1844 C C   . LEU B 2 30  C -10.238 14.146  -49.846 1.00 41.20  ? 27  LEU L C   1 
ATOM   1845 O O   . LEU B 2 30  C -10.243 12.958  -50.180 1.00 59.91  ? 27  LEU L O   1 
ATOM   1846 C CB  . LEU B 2 30  C -10.676 15.843  -51.640 1.00 34.64  ? 27  LEU L CB  1 
ATOM   1847 C CG  . LEU B 2 30  C -11.845 16.581  -50.982 1.00 34.92  ? 27  LEU L CG  1 
ATOM   1848 C CD1 . LEU B 2 30  C -11.340 17.598  -49.971 1.00 38.48  ? 27  LEU L CD1 1 
ATOM   1849 C CD2 . LEU B 2 30  C -12.715 17.256  -52.033 1.00 32.36  ? 27  LEU L CD2 1 
ATOM   1850 N N   . TYR B 2 31  D -10.761 14.580  -48.702 1.00 45.29  ? 27  TYR L N   1 
ATOM   1851 C CA  . TYR B 2 31  D -11.350 13.682  -47.717 1.00 57.61  ? 27  TYR L CA  1 
ATOM   1852 C C   . TYR B 2 31  D -12.653 14.295  -47.228 1.00 59.81  ? 27  TYR L C   1 
ATOM   1853 O O   . TYR B 2 31  D -12.650 15.404  -46.689 1.00 61.56  ? 27  TYR L O   1 
ATOM   1854 C CB  . TYR B 2 31  D -10.384 13.451  -46.556 1.00 40.40  ? 27  TYR L CB  1 
ATOM   1855 C CG  . TYR B 2 31  D -10.891 12.505  -45.502 1.00 55.88  ? 27  TYR L CG  1 
ATOM   1856 C CD1 . TYR B 2 31  D -10.443 12.606  -44.198 1.00 68.41  ? 27  TYR L CD1 1 
ATOM   1857 C CD2 . TYR B 2 31  D -11.802 11.501  -45.809 1.00 65.21  ? 27  TYR L CD2 1 
ATOM   1858 C CE1 . TYR B 2 31  D -10.890 11.753  -43.230 1.00 75.75  ? 27  TYR L CE1 1 
ATOM   1859 C CE2 . TYR B 2 31  D -12.259 10.635  -44.836 1.00 69.26  ? 27  TYR L CE2 1 
ATOM   1860 C CZ  . TYR B 2 31  D -11.796 10.768  -43.545 1.00 79.88  ? 27  TYR L CZ  1 
ATOM   1861 O OH  . TYR B 2 31  D -12.232 9.920   -42.554 1.00 85.39  ? 27  TYR L OH  1 
ATOM   1862 N N   . SER B 2 32  E -13.758 13.564  -47.399 1.00 58.48  ? 27  SER L N   1 
ATOM   1863 C CA  . SER B 2 32  E -15.079 14.146  -47.179 1.00 57.38  ? 27  SER L CA  1 
ATOM   1864 C C   . SER B 2 32  E -15.368 14.411  -45.705 1.00 63.66  ? 27  SER L C   1 
ATOM   1865 O O   . SER B 2 32  E -16.055 15.387  -45.382 1.00 67.70  ? 27  SER L O   1 
ATOM   1866 C CB  . SER B 2 32  E -16.155 13.235  -47.767 1.00 68.17  ? 27  SER L CB  1 
ATOM   1867 O OG  . SER B 2 32  E -15.985 13.083  -49.165 1.00 73.09  ? 27  SER L OG  1 
ATOM   1868 N N   . SER B 2 33  F -14.876 13.559  -44.802 1.00 61.21  ? 27  SER L N   1 
ATOM   1869 C CA  . SER B 2 33  F -15.217 13.714  -43.390 1.00 73.82  ? 27  SER L CA  1 
ATOM   1870 C C   . SER B 2 33  F -14.698 15.030  -42.821 1.00 79.18  ? 27  SER L C   1 
ATOM   1871 O O   . SER B 2 33  F -15.311 15.594  -41.908 1.00 84.38  ? 27  SER L O   1 
ATOM   1872 C CB  . SER B 2 33  F -14.673 12.539  -42.580 1.00 76.98  ? 27  SER L CB  1 
ATOM   1873 O OG  . SER B 2 33  F -13.434 12.868  -41.977 1.00 66.97  ? 27  SER L OG  1 
ATOM   1874 N N   . ILE B 2 34  ? -13.572 15.523  -43.332 1.00 72.27  ? 28  ILE L N   1 
ATOM   1875 C CA  . ILE B 2 34  ? -13.048 16.823  -42.937 1.00 56.94  ? 28  ILE L CA  1 
ATOM   1876 C C   . ILE B 2 34  ? -13.227 17.874  -44.031 1.00 59.37  ? 28  ILE L C   1 
ATOM   1877 O O   . ILE B 2 34  ? -13.239 19.075  -43.716 1.00 54.86  ? 28  ILE L O   1 
ATOM   1878 C CB  . ILE B 2 34  ? -11.562 16.721  -42.527 1.00 50.55  ? 28  ILE L CB  1 
ATOM   1879 C CG1 . ILE B 2 34  ? -11.352 15.554  -41.561 1.00 62.08  ? 28  ILE L CG1 1 
ATOM   1880 C CG2 . ILE B 2 34  ? -11.082 18.007  -41.870 1.00 65.59  ? 28  ILE L CG2 1 
ATOM   1881 C CD1 . ILE B 2 34  ? -11.993 15.759  -40.205 1.00 61.43  ? 28  ILE L CD1 1 
ATOM   1882 N N   . ASN B 2 35  ? -13.407 17.464  -45.289 1.00 60.69  ? 29  ASN L N   1 
ATOM   1883 C CA  . ASN B 2 35  ? -13.464 18.372  -46.436 1.00 51.35  ? 29  ASN L CA  1 
ATOM   1884 C C   . ASN B 2 35  ? -12.207 19.238  -46.512 1.00 52.26  ? 29  ASN L C   1 
ATOM   1885 O O   . ASN B 2 35  ? -12.266 20.452  -46.718 1.00 64.76  ? 29  ASN L O   1 
ATOM   1886 C CB  . ASN B 2 35  ? -14.726 19.234  -46.412 1.00 55.48  ? 29  ASN L CB  1 
ATOM   1887 C CG  . ASN B 2 35  ? -15.015 19.876  -47.756 1.00 64.35  ? 29  ASN L CG  1 
ATOM   1888 O OD1 . ASN B 2 35  ? -14.776 19.278  -48.808 1.00 40.10  ? 29  ASN L OD1 1 
ATOM   1889 N ND2 . ASN B 2 35  ? -15.518 21.104  -47.729 1.00 62.89  ? 29  ASN L ND2 1 
ATOM   1890 N N   . LYS B 2 36  ? -11.056 18.596  -46.328 1.00 49.23  ? 30  LYS L N   1 
ATOM   1891 C CA  . LYS B 2 36  ? -9.768  19.257  -46.472 1.00 54.03  ? 30  LYS L CA  1 
ATOM   1892 C C   . LYS B 2 36  ? -8.826  18.343  -47.237 1.00 51.76  ? 30  LYS L C   1 
ATOM   1893 O O   . LYS B 2 36  ? -8.702  17.160  -46.907 1.00 45.94  ? 30  LYS L O   1 
ATOM   1894 C CB  . LYS B 2 36  ? -9.173  19.626  -45.108 1.00 35.38  ? 30  LYS L CB  1 
ATOM   1895 C CG  . LYS B 2 36  ? -9.933  20.735  -44.404 1.00 48.24  ? 30  LYS L CG  1 
ATOM   1896 C CD  . LYS B 2 36  ? -8.985  21.749  -43.793 1.00 52.03  ? 30  LYS L CD  1 
ATOM   1897 C CE  . LYS B 2 36  ? -9.698  23.055  -43.489 1.00 45.10  ? 30  LYS L CE  1 
ATOM   1898 N NZ  . LYS B 2 36  ? -10.254 23.674  -44.726 1.00 60.03  ? 30  LYS L NZ  1 
ATOM   1899 N N   . ASN B 2 37  ? -8.176  18.891  -48.260 1.00 38.93  ? 31  ASN L N   1 
ATOM   1900 C CA  . ASN B 2 37  ? -7.216  18.120  -49.037 1.00 39.16  ? 31  ASN L CA  1 
ATOM   1901 C C   . ASN B 2 37  ? -5.937  17.924  -48.237 1.00 43.41  ? 31  ASN L C   1 
ATOM   1902 O O   . ASN B 2 37  ? -5.389  18.877  -47.677 1.00 41.54  ? 31  ASN L O   1 
ATOM   1903 C CB  . ASN B 2 37  ? -6.917  18.830  -50.355 1.00 42.25  ? 31  ASN L CB  1 
ATOM   1904 C CG  . ASN B 2 37  ? -8.129  18.913  -51.260 1.00 44.59  ? 31  ASN L CG  1 
ATOM   1905 O OD1 . ASN B 2 37  ? -8.293  18.103  -52.173 1.00 49.52  ? 31  ASN L OD1 1 
ATOM   1906 N ND2 . ASN B 2 37  ? -8.988  19.894  -51.011 1.00 43.84  ? 31  ASN L ND2 1 
ATOM   1907 N N   . TYR B 2 38  ? -5.456  16.684  -48.186 1.00 41.67  ? 32  TYR L N   1 
ATOM   1908 C CA  . TYR B 2 38  ? -4.275  16.347  -47.388 1.00 35.59  ? 32  TYR L CA  1 
ATOM   1909 C C   . TYR B 2 38  ? -2.998  16.613  -48.190 1.00 35.77  ? 32  TYR L C   1 
ATOM   1910 O O   . TYR B 2 38  ? -2.221  15.716  -48.521 1.00 34.28  ? 32  TYR L O   1 
ATOM   1911 C CB  . TYR B 2 38  ? -4.359  14.904  -46.908 1.00 28.07  ? 32  TYR L CB  1 
ATOM   1912 C CG  . TYR B 2 38  ? -5.267  14.729  -45.706 1.00 33.73  ? 32  TYR L CG  1 
ATOM   1913 C CD1 . TYR B 2 38  ? -6.572  15.209  -45.717 1.00 29.96  ? 32  TYR L CD1 1 
ATOM   1914 C CD2 . TYR B 2 38  ? -4.821  14.083  -44.561 1.00 34.04  ? 32  TYR L CD2 1 
ATOM   1915 C CE1 . TYR B 2 38  ? -7.401  15.057  -44.623 1.00 25.57  ? 32  TYR L CE1 1 
ATOM   1916 C CE2 . TYR B 2 38  ? -5.642  13.926  -43.462 1.00 33.86  ? 32  TYR L CE2 1 
ATOM   1917 C CZ  . TYR B 2 38  ? -6.931  14.414  -43.498 1.00 31.83  ? 32  TYR L CZ  1 
ATOM   1918 O OH  . TYR B 2 38  ? -7.753  14.257  -42.406 1.00 39.16  ? 32  TYR L OH  1 
ATOM   1919 N N   . LEU B 2 39  ? -2.798  17.893  -48.493 1.00 38.01  ? 33  LEU L N   1 
ATOM   1920 C CA  . LEU B 2 39  ? -1.684  18.373  -49.296 1.00 33.22  ? 33  LEU L CA  1 
ATOM   1921 C C   . LEU B 2 39  ? -0.866  19.363  -48.477 1.00 41.34  ? 33  LEU L C   1 
ATOM   1922 O O   . LEU B 2 39  ? -1.424  20.194  -47.753 1.00 42.13  ? 33  LEU L O   1 
ATOM   1923 C CB  . LEU B 2 39  ? -2.192  19.042  -50.584 1.00 37.68  ? 33  LEU L CB  1 
ATOM   1924 C CG  . LEU B 2 39  ? -1.298  19.145  -51.827 1.00 37.24  ? 33  LEU L CG  1 
ATOM   1925 C CD1 . LEU B 2 39  ? -0.195  20.186  -51.668 1.00 38.17  ? 33  LEU L CD1 1 
ATOM   1926 C CD2 . LEU B 2 39  ? -0.714  17.784  -52.176 1.00 35.56  ? 33  LEU L CD2 1 
ATOM   1927 N N   . ALA B 2 40  ? 0.457   19.273  -48.595 1.00 38.15  ? 34  ALA L N   1 
ATOM   1928 C CA  . ALA B 2 40  ? 1.366   20.148  -47.870 1.00 28.32  ? 34  ALA L CA  1 
ATOM   1929 C C   . ALA B 2 40  ? 2.393   20.738  -48.826 1.00 30.61  ? 34  ALA L C   1 
ATOM   1930 O O   . ALA B 2 40  ? 2.679   20.179  -49.888 1.00 39.28  ? 34  ALA L O   1 
ATOM   1931 C CB  . ALA B 2 40  ? 2.080   19.409  -46.730 1.00 30.43  ? 34  ALA L CB  1 
ATOM   1932 N N   . TRP B 2 41  ? 2.938   21.889  -48.436 1.00 39.40  ? 35  TRP L N   1 
ATOM   1933 C CA  . TRP B 2 41  ? 4.001   22.560  -49.169 1.00 29.57  ? 35  TRP L CA  1 
ATOM   1934 C C   . TRP B 2 41  ? 5.201   22.761  -48.254 1.00 29.32  ? 35  TRP L C   1 
ATOM   1935 O O   . TRP B 2 41  ? 5.048   23.134  -47.087 1.00 33.49  ? 35  TRP L O   1 
ATOM   1936 C CB  . TRP B 2 41  ? 3.537   23.912  -49.720 1.00 29.71  ? 35  TRP L CB  1 
ATOM   1937 C CG  . TRP B 2 41  ? 2.581   23.799  -50.861 1.00 26.12  ? 35  TRP L CG  1 
ATOM   1938 C CD1 . TRP B 2 41  ? 1.219   23.838  -50.796 1.00 43.66  ? 35  TRP L CD1 1 
ATOM   1939 C CD2 . TRP B 2 41  ? 2.912   23.631  -52.245 1.00 26.65  ? 35  TRP L CD2 1 
ATOM   1940 N NE1 . TRP B 2 41  ? 0.681   23.704  -52.054 1.00 42.28  ? 35  TRP L NE1 1 
ATOM   1941 C CE2 . TRP B 2 41  ? 1.700   23.575  -52.961 1.00 30.98  ? 35  TRP L CE2 1 
ATOM   1942 C CE3 . TRP B 2 41  ? 4.116   23.520  -52.947 1.00 35.32  ? 35  TRP L CE3 1 
ATOM   1943 C CZ2 . TRP B 2 41  ? 1.656   23.414  -54.344 1.00 33.49  ? 35  TRP L CZ2 1 
ATOM   1944 C CZ3 . TRP B 2 41  ? 4.070   23.360  -54.322 1.00 32.15  ? 35  TRP L CZ3 1 
ATOM   1945 C CH2 . TRP B 2 41  ? 2.849   23.310  -55.005 1.00 39.39  ? 35  TRP L CH2 1 
ATOM   1946 N N   . TYR B 2 42  ? 6.393   22.519  -48.792 1.00 32.99  ? 36  TYR L N   1 
ATOM   1947 C CA  . TYR B 2 42  ? 7.628   22.631  -48.032 1.00 33.11  ? 36  TYR L CA  1 
ATOM   1948 C C   . TYR B 2 42  ? 8.622   23.510  -48.777 1.00 36.67  ? 36  TYR L C   1 
ATOM   1949 O O   . TYR B 2 42  ? 8.622   23.574  -50.009 1.00 34.97  ? 36  TYR L O   1 
ATOM   1950 C CB  . TYR B 2 42  ? 8.253   21.257  -47.767 1.00 19.10  ? 36  TYR L CB  1 
ATOM   1951 C CG  . TYR B 2 42  ? 7.444   20.385  -46.836 1.00 29.65  ? 36  TYR L CG  1 
ATOM   1952 C CD1 . TYR B 2 42  ? 6.443   19.555  -47.324 1.00 36.01  ? 36  TYR L CD1 1 
ATOM   1953 C CD2 . TYR B 2 42  ? 7.684   20.388  -45.468 1.00 35.50  ? 36  TYR L CD2 1 
ATOM   1954 C CE1 . TYR B 2 42  ? 5.702   18.754  -46.475 1.00 32.35  ? 36  TYR L CE1 1 
ATOM   1955 C CE2 . TYR B 2 42  ? 6.948   19.591  -44.612 1.00 37.22  ? 36  TYR L CE2 1 
ATOM   1956 C CZ  . TYR B 2 42  ? 5.959   18.776  -45.121 1.00 33.99  ? 36  TYR L CZ  1 
ATOM   1957 O OH  . TYR B 2 42  ? 5.223   17.979  -44.273 1.00 30.35  ? 36  TYR L OH  1 
ATOM   1958 N N   . GLN B 2 43  ? 9.469   24.187  -48.008 1.00 40.73  ? 37  GLN L N   1 
ATOM   1959 C CA  . GLN B 2 43  ? 10.529  25.035  -48.535 1.00 30.85  ? 37  GLN L CA  1 
ATOM   1960 C C   . GLN B 2 43  ? 11.860  24.549  -47.983 1.00 38.99  ? 37  GLN L C   1 
ATOM   1961 O O   . GLN B 2 43  ? 11.979  24.297  -46.779 1.00 38.85  ? 37  GLN L O   1 
ATOM   1962 C CB  . GLN B 2 43  ? 10.302  26.500  -48.157 1.00 35.95  ? 37  GLN L CB  1 
ATOM   1963 C CG  . GLN B 2 43  ? 11.403  27.440  -48.612 1.00 46.34  ? 37  GLN L CG  1 
ATOM   1964 C CD  . GLN B 2 43  ? 11.330  28.793  -47.931 1.00 46.78  ? 37  GLN L CD  1 
ATOM   1965 O OE1 . GLN B 2 43  ? 11.330  28.883  -46.703 1.00 45.61  ? 37  GLN L OE1 1 
ATOM   1966 N NE2 . GLN B 2 43  ? 11.263  29.855  -48.727 1.00 45.43  ? 37  GLN L NE2 1 
ATOM   1967 N N   . GLN B 2 44  ? 12.856  24.415  -48.857 1.00 30.49  ? 38  GLN L N   1 
ATOM   1968 C CA  . GLN B 2 44  ? 14.183  23.948  -48.457 1.00 43.06  ? 38  GLN L CA  1 
ATOM   1969 C C   . GLN B 2 44  ? 15.237  24.894  -49.023 1.00 47.05  ? 38  GLN L C   1 
ATOM   1970 O O   . GLN B 2 44  ? 15.562  24.836  -50.213 1.00 32.38  ? 38  GLN L O   1 
ATOM   1971 C CB  . GLN B 2 44  ? 14.429  22.515  -48.918 1.00 41.87  ? 38  GLN L CB  1 
ATOM   1972 C CG  . GLN B 2 44  ? 15.685  21.902  -48.322 1.00 36.67  ? 38  GLN L CG  1 
ATOM   1973 C CD  . GLN B 2 44  ? 15.917  20.473  -48.765 1.00 42.73  ? 38  GLN L CD  1 
ATOM   1974 O OE1 . GLN B 2 44  ? 15.576  20.093  -49.886 1.00 55.55  ? 38  GLN L OE1 1 
ATOM   1975 N NE2 . GLN B 2 44  ? 16.499  19.669  -47.883 1.00 32.03  ? 38  GLN L NE2 1 
ATOM   1976 N N   . LYS B 2 45  ? 15.768  25.762  -48.166 1.00 40.62  ? 39  LYS L N   1 
ATOM   1977 C CA  . LYS B 2 45  ? 16.901  26.586  -48.544 1.00 42.03  ? 39  LYS L CA  1 
ATOM   1978 C C   . LYS B 2 45  ? 18.157  25.722  -48.652 1.00 57.04  ? 39  LYS L C   1 
ATOM   1979 O O   . LYS B 2 45  ? 18.242  24.659  -48.029 1.00 42.64  ? 39  LYS L O   1 
ATOM   1980 C CB  . LYS B 2 45  ? 17.113  27.698  -47.520 1.00 33.53  ? 39  LYS L CB  1 
ATOM   1981 C CG  . LYS B 2 45  ? 16.031  28.764  -47.538 1.00 37.46  ? 39  LYS L CG  1 
ATOM   1982 C CD  . LYS B 2 45  ? 15.993  29.537  -46.231 1.00 45.10  ? 39  LYS L CD  1 
ATOM   1983 C CE  . LYS B 2 45  ? 15.024  30.705  -46.307 1.00 43.86  ? 39  LYS L CE  1 
ATOM   1984 N NZ  . LYS B 2 45  ? 15.489  31.741  -47.270 1.00 50.78  ? 39  LYS L NZ  1 
ATOM   1985 N N   . PRO B 2 46  ? 19.137  26.142  -49.454 1.00 65.92  ? 40  PRO L N   1 
ATOM   1986 C CA  . PRO B 2 46  ? 20.368  25.350  -49.588 1.00 50.94  ? 40  PRO L CA  1 
ATOM   1987 C C   . PRO B 2 46  ? 21.041  25.133  -48.240 1.00 42.88  ? 40  PRO L C   1 
ATOM   1988 O O   . PRO B 2 46  ? 21.169  26.056  -47.432 1.00 46.23  ? 40  PRO L O   1 
ATOM   1989 C CB  . PRO B 2 46  ? 21.234  26.202  -50.523 1.00 51.64  ? 40  PRO L CB  1 
ATOM   1990 C CG  . PRO B 2 46  ? 20.253  27.002  -51.311 1.00 60.61  ? 40  PRO L CG  1 
ATOM   1991 C CD  . PRO B 2 46  ? 19.119  27.295  -50.371 1.00 52.14  ? 40  PRO L CD  1 
ATOM   1992 N N   . GLY B 2 47  ? 21.466  23.894  -48.000 1.00 37.29  ? 41  GLY L N   1 
ATOM   1993 C CA  . GLY B 2 47  ? 22.102  23.545  -46.746 1.00 36.23  ? 41  GLY L CA  1 
ATOM   1994 C C   . GLY B 2 47  ? 21.186  23.518  -45.546 1.00 43.95  ? 41  GLY L C   1 
ATOM   1995 O O   . GLY B 2 47  ? 21.665  23.325  -44.425 1.00 46.73  ? 41  GLY L O   1 
ATOM   1996 N N   . GLN B 2 48  ? 19.881  23.696  -45.743 1.00 50.86  ? 42  GLN L N   1 
ATOM   1997 C CA  . GLN B 2 48  ? 18.913  23.771  -44.664 1.00 33.44  ? 42  GLN L CA  1 
ATOM   1998 C C   . GLN B 2 48  ? 17.923  22.616  -44.751 1.00 38.78  ? 42  GLN L C   1 
ATOM   1999 O O   . GLN B 2 48  ? 17.660  22.098  -45.840 1.00 53.71  ? 42  GLN L O   1 
ATOM   2000 C CB  . GLN B 2 48  ? 18.142  25.097  -44.708 1.00 50.18  ? 42  GLN L CB  1 
ATOM   2001 C CG  . GLN B 2 48  ? 18.964  26.324  -44.345 1.00 56.46  ? 42  GLN L CG  1 
ATOM   2002 C CD  . GLN B 2 48  ? 19.007  26.581  -42.849 1.00 63.74  ? 42  GLN L CD  1 
ATOM   2003 O OE1 . GLN B 2 48  ? 18.663  25.712  -42.047 1.00 65.89  ? 42  GLN L OE1 1 
ATOM   2004 N NE2 . GLN B 2 48  ? 19.423  27.783  -42.468 1.00 63.30  ? 42  GLN L NE2 1 
ATOM   2005 N N   . PRO B 2 49  ? 17.372  22.182  -43.622 1.00 41.03  ? 43  PRO L N   1 
ATOM   2006 C CA  . PRO B 2 49  ? 16.288  21.194  -43.652 1.00 43.36  ? 43  PRO L CA  1 
ATOM   2007 C C   . PRO B 2 49  ? 15.011  21.809  -44.193 1.00 40.24  ? 43  PRO L C   1 
ATOM   2008 O O   . PRO B 2 49  ? 14.839  23.037  -44.157 1.00 37.96  ? 43  PRO L O   1 
ATOM   2009 C CB  . PRO B 2 49  ? 16.135  20.792  -42.177 1.00 34.75  ? 43  PRO L CB  1 
ATOM   2010 C CG  . PRO B 2 49  ? 16.686  21.946  -41.413 1.00 38.89  ? 43  PRO L CG  1 
ATOM   2011 C CD  . PRO B 2 49  ? 17.804  22.491  -42.249 1.00 41.46  ? 43  PRO L CD  1 
ATOM   2012 N N   . PRO B 2 50  ? 14.097  20.994  -44.719 1.00 45.70  ? 44  PRO L N   1 
ATOM   2013 C CA  . PRO B 2 50  ? 12.834  21.537  -45.232 1.00 39.71  ? 44  PRO L CA  1 
ATOM   2014 C C   . PRO B 2 50  ? 11.989  22.139  -44.119 1.00 41.17  ? 44  PRO L C   1 
ATOM   2015 O O   . PRO B 2 50  ? 12.021  21.693  -42.969 1.00 40.59  ? 44  PRO L O   1 
ATOM   2016 C CB  . PRO B 2 50  ? 12.144  20.316  -45.853 1.00 33.60  ? 44  PRO L CB  1 
ATOM   2017 C CG  . PRO B 2 50  ? 13.231  19.299  -46.038 1.00 35.28  ? 44  PRO L CG  1 
ATOM   2018 C CD  . PRO B 2 50  ? 14.201  19.541  -44.928 1.00 39.25  ? 44  PRO L CD  1 
ATOM   2019 N N   . LYS B 2 51  ? 11.221  23.166  -44.478 1.00 35.94  ? 45  LYS L N   1 
ATOM   2020 C CA  . LYS B 2 51  ? 10.326  23.847  -43.553 1.00 37.46  ? 45  LYS L CA  1 
ATOM   2021 C C   . LYS B 2 51  ? 8.910   23.833  -44.112 1.00 38.80  ? 45  LYS L C   1 
ATOM   2022 O O   . LYS B 2 51  ? 8.702   24.064  -45.308 1.00 39.84  ? 45  LYS L O   1 
ATOM   2023 C CB  . LYS B 2 51  ? 10.777  25.292  -43.298 1.00 46.51  ? 45  LYS L CB  1 
ATOM   2024 C CG  . LYS B 2 51  ? 10.018  25.987  -42.176 1.00 45.75  ? 45  LYS L CG  1 
ATOM   2025 C CD  . LYS B 2 51  ? 10.487  27.421  -41.976 1.00 54.77  ? 45  LYS L CD  1 
ATOM   2026 C CE  . LYS B 2 51  ? 10.091  28.306  -43.146 1.00 67.76  ? 45  LYS L CE  1 
ATOM   2027 N NZ  . LYS B 2 51  ? 10.408  29.739  -42.888 1.00 62.62  ? 45  LYS L NZ  1 
ATOM   2028 N N   . LEU B 2 52  ? 7.939   23.567  -43.241 1.00 29.28  ? 46  LEU L N   1 
ATOM   2029 C CA  . LEU B 2 52  ? 6.548   23.434  -43.658 1.00 30.36  ? 46  LEU L CA  1 
ATOM   2030 C C   . LEU B 2 52  ? 5.913   24.811  -43.809 1.00 31.87  ? 46  LEU L C   1 
ATOM   2031 O O   . LEU B 2 52  ? 5.771   25.549  -42.827 1.00 34.72  ? 46  LEU L O   1 
ATOM   2032 C CB  . LEU B 2 52  ? 5.771   22.592  -42.649 1.00 37.23  ? 46  LEU L CB  1 
ATOM   2033 C CG  . LEU B 2 52  ? 4.273   22.436  -42.921 1.00 37.85  ? 46  LEU L CG  1 
ATOM   2034 C CD1 . LEU B 2 52  ? 4.037   21.765  -44.265 1.00 34.73  ? 46  LEU L CD1 1 
ATOM   2035 C CD2 . LEU B 2 52  ? 3.596   21.657  -41.802 1.00 34.97  ? 46  LEU L CD2 1 
ATOM   2036 N N   . LEU B 2 53  ? 5.521   25.151  -45.037 1.00 37.28  ? 47  LEU L N   1 
ATOM   2037 C CA  . LEU B 2 53  ? 4.887   26.433  -45.327 1.00 38.39  ? 47  LEU L CA  1 
ATOM   2038 C C   . LEU B 2 53  ? 3.369   26.355  -45.192 1.00 38.82  ? 47  LEU L C   1 
ATOM   2039 O O   . LEU B 2 53  ? 2.765   27.120  -44.433 1.00 38.73  ? 47  LEU L O   1 
ATOM   2040 C CB  . LEU B 2 53  ? 5.258   26.899  -46.739 1.00 33.32  ? 47  LEU L CB  1 
ATOM   2041 C CG  . LEU B 2 53  ? 6.673   27.410  -46.992 1.00 50.41  ? 47  LEU L CG  1 
ATOM   2042 C CD1 . LEU B 2 53  ? 6.835   27.708  -48.466 1.00 46.65  ? 47  LEU L CD1 1 
ATOM   2043 C CD2 . LEU B 2 53  ? 6.948   28.651  -46.162 1.00 47.73  ? 47  LEU L CD2 1 
ATOM   2044 N N   . ILE B 2 54  ? 2.744   25.443  -45.930 1.00 39.19  ? 48  ILE L N   1 
ATOM   2045 C CA  . ILE B 2 54  ? 1.292   25.363  -46.028 1.00 39.74  ? 48  ILE L CA  1 
ATOM   2046 C C   . ILE B 2 54  ? 0.865   23.913  -45.843 1.00 36.43  ? 48  ILE L C   1 
ATOM   2047 O O   . ILE B 2 54  ? 1.464   23.006  -46.430 1.00 47.18  ? 48  ILE L O   1 
ATOM   2048 C CB  . ILE B 2 54  ? 0.793   25.920  -47.375 1.00 31.14  ? 48  ILE L CB  1 
ATOM   2049 C CG1 . ILE B 2 54  ? 0.784   27.449  -47.329 1.00 38.11  ? 48  ILE L CG1 1 
ATOM   2050 C CG2 . ILE B 2 54  ? -0.585  25.370  -47.723 1.00 28.93  ? 48  ILE L CG2 1 
ATOM   2051 C CD1 . ILE B 2 54  ? 1.041   28.104  -48.660 1.00 35.23  ? 48  ILE L CD1 1 
ATOM   2052 N N   . TYR B 2 55  ? -0.160  23.699  -45.021 1.00 29.72  ? 49  TYR L N   1 
ATOM   2053 C CA  . TYR B 2 55  ? -0.742  22.386  -44.799 1.00 31.89  ? 49  TYR L CA  1 
ATOM   2054 C C   . TYR B 2 55  ? -2.234  22.436  -45.106 1.00 39.78  ? 49  TYR L C   1 
ATOM   2055 O O   . TYR B 2 55  ? -2.868  23.494  -45.042 1.00 44.72  ? 49  TYR L O   1 
ATOM   2056 C CB  . TYR B 2 55  ? -0.504  21.902  -43.360 1.00 38.34  ? 49  TYR L CB  1 
ATOM   2057 C CG  . TYR B 2 55  ? -1.158  22.761  -42.301 1.00 46.84  ? 49  TYR L CG  1 
ATOM   2058 C CD1 . TYR B 2 55  ? -0.511  23.876  -41.784 1.00 45.01  ? 49  TYR L CD1 1 
ATOM   2059 C CD2 . TYR B 2 55  ? -2.420  22.450  -41.811 1.00 53.51  ? 49  TYR L CD2 1 
ATOM   2060 C CE1 . TYR B 2 55  ? -1.106  24.660  -40.814 1.00 54.57  ? 49  TYR L CE1 1 
ATOM   2061 C CE2 . TYR B 2 55  ? -3.022  23.228  -40.844 1.00 53.36  ? 49  TYR L CE2 1 
ATOM   2062 C CZ  . TYR B 2 55  ? -2.361  24.331  -40.347 1.00 57.96  ? 49  TYR L CZ  1 
ATOM   2063 O OH  . TYR B 2 55  ? -2.956  25.110  -39.382 1.00 58.09  ? 49  TYR L OH  1 
ATOM   2064 N N   . TRP B 2 56  ? -2.786  21.273  -45.454 1.00 32.31  ? 50  TRP L N   1 
ATOM   2065 C CA  . TRP B 2 56  ? -4.181  21.150  -45.894 1.00 32.26  ? 50  TRP L CA  1 
ATOM   2066 C C   . TRP B 2 56  ? -4.467  22.028  -47.111 1.00 34.48  ? 50  TRP L C   1 
ATOM   2067 O O   . TRP B 2 56  ? -5.603  22.458  -47.331 1.00 32.64  ? 50  TRP L O   1 
ATOM   2068 C CB  . TRP B 2 56  ? -5.159  21.450  -44.755 1.00 30.05  ? 50  TRP L CB  1 
ATOM   2069 C CG  . TRP B 2 56  ? -5.571  20.222  -44.007 1.00 38.06  ? 50  TRP L CG  1 
ATOM   2070 C CD1 . TRP B 2 56  ? -5.554  18.936  -44.469 1.00 39.96  ? 50  TRP L CD1 1 
ATOM   2071 C CD2 . TRP B 2 56  ? -6.052  20.160  -42.662 1.00 40.72  ? 50  TRP L CD2 1 
ATOM   2072 N NE1 . TRP B 2 56  ? -6.001  18.078  -43.493 1.00 33.42  ? 50  TRP L NE1 1 
ATOM   2073 C CE2 . TRP B 2 56  ? -6.313  18.805  -42.373 1.00 39.88  ? 50  TRP L CE2 1 
ATOM   2074 C CE3 . TRP B 2 56  ? -6.289  21.118  -41.672 1.00 38.12  ? 50  TRP L CE3 1 
ATOM   2075 C CZ2 . TRP B 2 56  ? -6.799  18.386  -41.137 1.00 46.31  ? 50  TRP L CZ2 1 
ATOM   2076 C CZ3 . TRP B 2 56  ? -6.772  20.700  -40.446 1.00 39.49  ? 50  TRP L CZ3 1 
ATOM   2077 C CH2 . TRP B 2 56  ? -7.022  19.346  -40.189 1.00 42.68  ? 50  TRP L CH2 1 
ATOM   2078 N N   . ALA B 2 57  ? -3.403  22.310  -47.874 1.00 31.35  ? 51  ALA L N   1 
ATOM   2079 C CA  . ALA B 2 57  ? -3.434  22.885  -49.217 1.00 28.65  ? 51  ALA L CA  1 
ATOM   2080 C C   . ALA B 2 57  ? -3.807  24.361  -49.241 1.00 34.98  ? 51  ALA L C   1 
ATOM   2081 O O   . ALA B 2 57  ? -3.734  24.999  -50.294 1.00 49.98  ? 51  ALA L O   1 
ATOM   2082 C CB  . ALA B 2 57  ? -4.403  22.101  -50.106 1.00 33.34  ? 51  ALA L CB  1 
ATOM   2083 N N   . SER B 2 58  ? -4.183  24.921  -48.095 1.00 38.61  ? 52  SER L N   1 
ATOM   2084 C CA  . SER B 2 58  ? -4.584  26.325  -48.025 1.00 37.39  ? 52  SER L CA  1 
ATOM   2085 C C   . SER B 2 58  ? -4.151  27.030  -46.749 1.00 45.87  ? 52  SER L C   1 
ATOM   2086 O O   . SER B 2 58  ? -3.994  28.258  -46.769 1.00 43.08  ? 52  SER L O   1 
ATOM   2087 C CB  . SER B 2 58  ? -6.112  26.467  -48.178 1.00 42.30  ? 52  SER L CB  1 
ATOM   2088 O OG  . SER B 2 58  ? -6.824  26.042  -47.025 1.00 59.12  ? 52  SER L OG  1 
ATOM   2089 N N   . THR B 2 59  ? -3.927  26.304  -45.658 1.00 40.30  ? 53  THR L N   1 
ATOM   2090 C CA  . THR B 2 59  ? -3.642  26.910  -44.367 1.00 38.39  ? 53  THR L CA  1 
ATOM   2091 C C   . THR B 2 59  ? -2.139  27.021  -44.150 1.00 43.97  ? 53  THR L C   1 
ATOM   2092 O O   . THR B 2 59  ? -1.393  26.067  -44.394 1.00 51.52  ? 53  THR L O   1 
ATOM   2093 C CB  . THR B 2 59  ? -4.279  26.090  -43.244 1.00 43.85  ? 53  THR L CB  1 
ATOM   2094 O OG1 . THR B 2 59  ? -5.659  25.861  -43.553 1.00 39.59  ? 53  THR L OG1 1 
ATOM   2095 C CG2 . THR B 2 59  ? -4.184  26.835  -41.925 1.00 39.06  ? 53  THR L CG2 1 
ATOM   2096 N N   . ARG B 2 60  ? -1.705  28.188  -43.685 1.00 44.51  ? 54  ARG L N   1 
ATOM   2097 C CA  . ARG B 2 60  ? -0.296  28.471  -43.465 1.00 43.04  ? 54  ARG L CA  1 
ATOM   2098 C C   . ARG B 2 60  ? 0.120   28.099  -42.049 1.00 43.26  ? 54  ARG L C   1 
ATOM   2099 O O   . ARG B 2 60  ? -0.649  28.242  -41.094 1.00 41.26  ? 54  ARG L O   1 
ATOM   2100 C CB  . ARG B 2 60  ? 0.005   29.951  -43.705 1.00 28.66  ? 54  ARG L CB  1 
ATOM   2101 C CG  . ARG B 2 60  ? -0.161  30.409  -45.136 1.00 42.49  ? 54  ARG L CG  1 
ATOM   2102 C CD  . ARG B 2 60  ? 0.294   31.850  -45.281 1.00 42.84  ? 54  ARG L CD  1 
ATOM   2103 N NE  . ARG B 2 60  ? -0.408  32.736  -44.360 1.00 51.20  ? 54  ARG L NE  1 
ATOM   2104 C CZ  . ARG B 2 60  ? -1.573  33.313  -44.619 1.00 61.63  ? 54  ARG L CZ  1 
ATOM   2105 N NH1 . ARG B 2 60  ? -2.200  33.119  -45.768 1.00 45.55  ? 54  ARG L NH1 1 
ATOM   2106 N NH2 . ARG B 2 60  ? -2.124  34.103  -43.701 1.00 70.36  ? 54  ARG L NH2 1 
ATOM   2107 N N   . GLU B 2 61  ? 1.353   27.618  -41.927 1.00 41.85  ? 55  GLU L N   1 
ATOM   2108 C CA  . GLU B 2 61  ? 1.958   27.417  -40.620 1.00 41.14  ? 55  GLU L CA  1 
ATOM   2109 C C   . GLU B 2 61  ? 2.194   28.760  -39.940 1.00 50.04  ? 55  GLU L C   1 
ATOM   2110 O O   . GLU B 2 61  ? 2.353   29.794  -40.595 1.00 55.02  ? 55  GLU L O   1 
ATOM   2111 C CB  . GLU B 2 61  ? 3.279   26.660  -40.753 1.00 40.06  ? 55  GLU L CB  1 
ATOM   2112 C CG  . GLU B 2 61  ? 3.242   25.226  -40.255 1.00 46.03  ? 55  GLU L CG  1 
ATOM   2113 C CD  . GLU B 2 61  ? 2.943   25.130  -38.771 1.00 61.59  ? 55  GLU L CD  1 
ATOM   2114 O OE1 . GLU B 2 61  ? 1.749   25.122  -38.401 1.00 57.16  ? 55  GLU L OE1 1 
ATOM   2115 O OE2 . GLU B 2 61  ? 3.902   25.071  -37.973 1.00 80.35  ? 55  GLU L OE2 1 
ATOM   2116 N N   . SER B 2 62  ? 2.205   28.741  -38.609 1.00 41.95  ? 56  SER L N   1 
ATOM   2117 C CA  . SER B 2 62  ? 2.460   29.962  -37.859 1.00 48.09  ? 56  SER L CA  1 
ATOM   2118 C C   . SER B 2 62  ? 3.864   30.475  -38.157 1.00 52.91  ? 56  SER L C   1 
ATOM   2119 O O   . SER B 2 62  ? 4.827   29.706  -38.210 1.00 51.95  ? 56  SER L O   1 
ATOM   2120 C CB  . SER B 2 62  ? 2.291   29.716  -36.359 1.00 44.27  ? 56  SER L CB  1 
ATOM   2121 O OG  . SER B 2 62  ? 3.537   29.437  -35.745 1.00 72.58  ? 56  SER L OG  1 
ATOM   2122 N N   . GLY B 2 63  ? 3.974   31.787  -38.358 1.00 44.23  ? 57  GLY L N   1 
ATOM   2123 C CA  . GLY B 2 63  ? 5.226   32.403  -38.736 1.00 34.23  ? 57  GLY L CA  1 
ATOM   2124 C C   . GLY B 2 63  ? 5.456   32.530  -40.227 1.00 33.29  ? 57  GLY L C   1 
ATOM   2125 O O   . GLY B 2 63  ? 6.428   33.179  -40.633 1.00 48.35  ? 57  GLY L O   1 
ATOM   2126 N N   . VAL B 2 64  ? 4.604   31.933  -41.050 1.00 40.22  ? 58  VAL L N   1 
ATOM   2127 C CA  . VAL B 2 64  ? 4.726   32.067  -42.503 1.00 42.29  ? 58  VAL L CA  1 
ATOM   2128 C C   . VAL B 2 64  ? 4.102   33.394  -42.928 1.00 39.06  ? 58  VAL L C   1 
ATOM   2129 O O   . VAL B 2 64  ? 2.947   33.669  -42.566 1.00 41.44  ? 58  VAL L O   1 
ATOM   2130 C CB  . VAL B 2 64  ? 4.058   30.891  -43.211 1.00 42.41  ? 58  VAL L CB  1 
ATOM   2131 C CG1 . VAL B 2 64  ? 4.098   31.087  -44.719 1.00 39.20  ? 58  VAL L CG1 1 
ATOM   2132 C CG2 . VAL B 2 64  ? 4.737   29.582  -42.825 1.00 34.30  ? 58  VAL L CG2 1 
ATOM   2133 N N   . PRO B 2 65  ? 4.823   34.234  -43.670 1.00 40.09  ? 59  PRO L N   1 
ATOM   2134 C CA  . PRO B 2 65  ? 4.261   35.523  -44.091 1.00 44.55  ? 59  PRO L CA  1 
ATOM   2135 C C   . PRO B 2 65  ? 3.085   35.341  -45.040 1.00 52.78  ? 59  PRO L C   1 
ATOM   2136 O O   . PRO B 2 65  ? 2.922   34.296  -45.677 1.00 52.26  ? 59  PRO L O   1 
ATOM   2137 C CB  . PRO B 2 65  ? 5.440   36.217  -44.786 1.00 52.88  ? 59  PRO L CB  1 
ATOM   2138 C CG  . PRO B 2 65  ? 6.364   35.102  -45.176 1.00 41.24  ? 59  PRO L CG  1 
ATOM   2139 C CD  . PRO B 2 65  ? 6.218   34.062  -44.109 1.00 45.43  ? 59  PRO L CD  1 
ATOM   2140 N N   . ASP B 2 66  ? 2.252   36.388  -45.130 1.00 55.42  ? 60  ASP L N   1 
ATOM   2141 C CA  . ASP B 2 66  ? 1.004   36.274  -45.880 1.00 49.75  ? 60  ASP L CA  1 
ATOM   2142 C C   . ASP B 2 66  ? 1.239   36.057  -47.367 1.00 53.76  ? 60  ASP L C   1 
ATOM   2143 O O   . ASP B 2 66  ? 0.339   35.565  -48.056 1.00 59.22  ? 60  ASP L O   1 
ATOM   2144 C CB  . ASP B 2 66  ? 0.092   37.501  -45.637 1.00 57.18  ? 60  ASP L CB  1 
ATOM   2145 C CG  . ASP B 2 66  ? 0.438   38.734  -46.496 1.00 83.32  ? 60  ASP L CG  1 
ATOM   2146 O OD1 . ASP B 2 66  ? 1.054   38.629  -47.580 1.00 90.46  ? 60  ASP L OD1 1 
ATOM   2147 O OD2 . ASP B 2 66  ? 0.051   39.843  -46.066 1.00 89.94  ? 60  ASP L OD2 1 
ATOM   2148 N N   . ARG B 2 67  ? 2.416   36.425  -47.882 1.00 46.84  ? 61  ARG L N   1 
ATOM   2149 C CA  . ARG B 2 67  ? 2.655   36.357  -49.319 1.00 49.54  ? 61  ARG L CA  1 
ATOM   2150 C C   . ARG B 2 67  ? 2.653   34.928  -49.848 1.00 54.75  ? 61  ARG L C   1 
ATOM   2151 O O   . ARG B 2 67  ? 2.560   34.731  -51.064 1.00 48.83  ? 61  ARG L O   1 
ATOM   2152 C CB  . ARG B 2 67  ? 3.973   37.055  -49.666 1.00 54.24  ? 61  ARG L CB  1 
ATOM   2153 C CG  . ARG B 2 67  ? 5.179   36.589  -48.865 1.00 53.34  ? 61  ARG L CG  1 
ATOM   2154 C CD  . ARG B 2 67  ? 6.387   37.475  -49.145 1.00 48.01  ? 61  ARG L CD  1 
ATOM   2155 N NE  . ARG B 2 67  ? 7.645   36.795  -48.861 1.00 48.17  ? 61  ARG L NE  1 
ATOM   2156 C CZ  . ARG B 2 67  ? 8.312   36.890  -47.719 1.00 52.68  ? 61  ARG L CZ  1 
ATOM   2157 N NH1 . ARG B 2 67  ? 7.867   37.632  -46.717 1.00 53.32  ? 61  ARG L NH1 1 
ATOM   2158 N NH2 . ARG B 2 67  ? 9.457   36.228  -47.579 1.00 48.18  ? 61  ARG L NH2 1 
ATOM   2159 N N   . PHE B 2 68  ? 2.758   33.932  -48.973 1.00 49.09  ? 62  PHE L N   1 
ATOM   2160 C CA  . PHE B 2 68  ? 2.568   32.542  -49.359 1.00 46.89  ? 62  PHE L CA  1 
ATOM   2161 C C   . PHE B 2 68  ? 1.085   32.202  -49.294 1.00 49.75  ? 62  PHE L C   1 
ATOM   2162 O O   . PHE B 2 68  ? 0.416   32.502  -48.301 1.00 49.81  ? 62  PHE L O   1 
ATOM   2163 C CB  . PHE B 2 68  ? 3.363   31.609  -48.447 1.00 39.93  ? 62  PHE L CB  1 
ATOM   2164 C CG  . PHE B 2 68  ? 4.851   31.770  -48.562 1.00 39.85  ? 62  PHE L CG  1 
ATOM   2165 C CD1 . PHE B 2 68  ? 5.516   32.724  -47.813 1.00 50.35  ? 62  PHE L CD1 1 
ATOM   2166 C CD2 . PHE B 2 68  ? 5.586   30.961  -49.413 1.00 50.36  ? 62  PHE L CD2 1 
ATOM   2167 C CE1 . PHE B 2 68  ? 6.885   32.873  -47.910 1.00 44.88  ? 62  PHE L CE1 1 
ATOM   2168 C CE2 . PHE B 2 68  ? 6.959   31.106  -49.515 1.00 50.62  ? 62  PHE L CE2 1 
ATOM   2169 C CZ  . PHE B 2 68  ? 7.608   32.063  -48.763 1.00 47.68  ? 62  PHE L CZ  1 
ATOM   2170 N N   . SER B 2 69  ? 0.572   31.589  -50.357 1.00 38.66  ? 63  SER L N   1 
ATOM   2171 C CA  . SER B 2 69  ? -0.830  31.198  -50.393 1.00 43.43  ? 63  SER L CA  1 
ATOM   2172 C C   . SER B 2 69  ? -0.967  29.905  -51.179 1.00 47.34  ? 63  SER L C   1 
ATOM   2173 O O   . SER B 2 69  ? -0.384  29.765  -52.259 1.00 47.96  ? 63  SER L O   1 
ATOM   2174 C CB  . SER B 2 69  ? -1.694  32.300  -51.016 1.00 35.93  ? 63  SER L CB  1 
ATOM   2175 O OG  . SER B 2 69  ? -1.268  32.603  -52.333 1.00 58.71  ? 63  SER L OG  1 
ATOM   2176 N N   . GLY B 2 70  ? -1.739  28.972  -50.638 1.00 44.47  ? 64  GLY L N   1 
ATOM   2177 C CA  . GLY B 2 70  ? -1.994  27.690  -51.279 1.00 44.91  ? 64  GLY L CA  1 
ATOM   2178 C C   . GLY B 2 70  ? -3.438  27.610  -51.742 1.00 48.95  ? 64  GLY L C   1 
ATOM   2179 O O   . GLY B 2 70  ? -4.341  28.123  -51.076 1.00 30.38  ? 64  GLY L O   1 
ATOM   2180 N N   . SER B 2 71  ? -3.645  26.962  -52.885 1.00 51.25  ? 65  SER L N   1 
ATOM   2181 C CA  . SER B 2 71  ? -4.976  26.796  -53.449 1.00 41.60  ? 65  SER L CA  1 
ATOM   2182 C C   . SER B 2 71  ? -5.045  25.442  -54.145 1.00 51.97  ? 65  SER L C   1 
ATOM   2183 O O   . SER B 2 71  ? -4.074  24.679  -54.165 1.00 52.32  ? 65  SER L O   1 
ATOM   2184 C CB  . SER B 2 71  ? -5.315  27.943  -54.407 1.00 38.78  ? 65  SER L CB  1 
ATOM   2185 O OG  . SER B 2 71  ? -4.377  28.019  -55.466 1.00 55.03  ? 65  SER L OG  1 
ATOM   2186 N N   . GLY B 2 72  ? -6.206  25.149  -54.719 1.00 60.51  ? 66  GLY L N   1 
ATOM   2187 C CA  . GLY B 2 72  ? -6.434  23.907  -55.426 1.00 42.18  ? 66  GLY L CA  1 
ATOM   2188 C C   . GLY B 2 72  ? -7.254  22.920  -54.612 1.00 42.98  ? 66  GLY L C   1 
ATOM   2189 O O   . GLY B 2 72  ? -7.459  23.064  -53.405 1.00 45.18  ? 66  GLY L O   1 
ATOM   2190 N N   . SER B 2 73  ? -7.736  21.894  -55.310 1.00 54.86  ? 67  SER L N   1 
ATOM   2191 C CA  . SER B 2 73  ? -8.525  20.845  -54.681 1.00 45.75  ? 67  SER L CA  1 
ATOM   2192 C C   . SER B 2 73  ? -8.515  19.619  -55.580 1.00 38.45  ? 67  SER L C   1 
ATOM   2193 O O   . SER B 2 73  ? -8.405  19.731  -56.804 1.00 33.65  ? 67  SER L O   1 
ATOM   2194 C CB  . SER B 2 73  ? -9.963  21.303  -54.413 1.00 44.41  ? 67  SER L CB  1 
ATOM   2195 O OG  . SER B 2 73  ? -10.692 20.308  -53.715 1.00 48.57  ? 67  SER L OG  1 
ATOM   2196 N N   . GLY B 2 74  ? -8.630  18.449  -54.957 1.00 38.19  ? 68  GLY L N   1 
ATOM   2197 C CA  . GLY B 2 74  ? -8.661  17.206  -55.700 1.00 43.78  ? 68  GLY L CA  1 
ATOM   2198 C C   . GLY B 2 74  ? -7.293  16.757  -56.167 1.00 41.18  ? 68  GLY L C   1 
ATOM   2199 O O   . GLY B 2 74  ? -6.474  16.293  -55.367 1.00 42.66  ? 68  GLY L O   1 
ATOM   2200 N N   . THR B 2 75  ? -7.036  16.887  -57.470 1.00 35.85  ? 69  THR L N   1 
ATOM   2201 C CA  . THR B 2 75  ? -5.779  16.459  -58.065 1.00 42.37  ? 69  THR L CA  1 
ATOM   2202 C C   . THR B 2 75  ? -4.889  17.609  -58.514 1.00 40.15  ? 69  THR L C   1 
ATOM   2203 O O   . THR B 2 75  ? -3.751  17.359  -58.925 1.00 48.35  ? 69  THR L O   1 
ATOM   2204 C CB  . THR B 2 75  ? -6.045  15.538  -59.265 1.00 45.15  ? 69  THR L CB  1 
ATOM   2205 O OG1 . THR B 2 75  ? -6.940  16.185  -60.178 1.00 47.47  ? 69  THR L OG1 1 
ATOM   2206 C CG2 . THR B 2 75  ? -6.659  14.225  -58.805 1.00 45.02  ? 69  THR L CG2 1 
ATOM   2207 N N   . ASP B 2 76  ? -5.364  18.851  -58.451 1.00 40.56  ? 70  ASP L N   1 
ATOM   2208 C CA  . ASP B 2 76  ? -4.604  20.011  -58.896 1.00 48.83  ? 70  ASP L CA  1 
ATOM   2209 C C   . ASP B 2 76  ? -4.426  20.983  -57.738 1.00 54.17  ? 70  ASP L C   1 
ATOM   2210 O O   . ASP B 2 76  ? -5.394  21.310  -57.043 1.00 47.26  ? 70  ASP L O   1 
ATOM   2211 C CB  . ASP B 2 76  ? -5.305  20.707  -60.067 1.00 45.99  ? 70  ASP L CB  1 
ATOM   2212 C CG  . ASP B 2 76  ? -5.599  19.762  -61.213 1.00 62.23  ? 70  ASP L CG  1 
ATOM   2213 O OD1 . ASP B 2 76  ? -4.777  18.851  -61.450 1.00 62.16  ? 70  ASP L OD1 1 
ATOM   2214 O OD2 . ASP B 2 76  ? -6.650  19.927  -61.870 1.00 71.32  ? 70  ASP L OD2 1 
ATOM   2215 N N   . PHE B 2 77  ? -3.190  21.438  -57.532 1.00 58.31  ? 71  PHE L N   1 
ATOM   2216 C CA  . PHE B 2 77  ? -2.877  22.410  -56.495 1.00 47.26  ? 71  PHE L CA  1 
ATOM   2217 C C   . PHE B 2 77  ? -1.822  23.377  -57.013 1.00 40.32  ? 71  PHE L C   1 
ATOM   2218 O O   . PHE B 2 77  ? -1.007  23.029  -57.871 1.00 49.60  ? 71  PHE L O   1 
ATOM   2219 C CB  . PHE B 2 77  ? -2.382  21.730  -55.213 1.00 39.10  ? 71  PHE L CB  1 
ATOM   2220 C CG  . PHE B 2 77  ? -3.382  20.793  -54.602 1.00 44.35  ? 71  PHE L CG  1 
ATOM   2221 C CD1 . PHE B 2 77  ? -4.353  21.266  -53.734 1.00 49.68  ? 71  PHE L CD1 1 
ATOM   2222 C CD2 . PHE B 2 77  ? -3.352  19.440  -54.894 1.00 34.82  ? 71  PHE L CD2 1 
ATOM   2223 C CE1 . PHE B 2 77  ? -5.276  20.407  -53.170 1.00 39.37  ? 71  PHE L CE1 1 
ATOM   2224 C CE2 . PHE B 2 77  ? -4.272  18.576  -54.334 1.00 37.23  ? 71  PHE L CE2 1 
ATOM   2225 C CZ  . PHE B 2 77  ? -5.236  19.061  -53.471 1.00 47.63  ? 71  PHE L CZ  1 
ATOM   2226 N N   . THR B 2 78  ? -1.852  24.604  -56.491 1.00 35.51  ? 72  THR L N   1 
ATOM   2227 C CA  . THR B 2 78  ? -0.881  25.625  -56.859 1.00 47.41  ? 72  THR L CA  1 
ATOM   2228 C C   . THR B 2 78  ? -0.405  26.359  -55.614 1.00 49.06  ? 72  THR L C   1 
ATOM   2229 O O   . THR B 2 78  ? -1.200  26.667  -54.721 1.00 39.94  ? 72  THR L O   1 
ATOM   2230 C CB  . THR B 2 78  ? -1.458  26.647  -57.853 1.00 46.20  ? 72  THR L CB  1 
ATOM   2231 O OG1 . THR B 2 78  ? -2.482  27.417  -57.212 1.00 64.35  ? 72  THR L OG1 1 
ATOM   2232 C CG2 . THR B 2 78  ? -2.040  25.956  -59.080 1.00 50.31  ? 72  THR L CG2 1 
ATOM   2233 N N   . LEU B 2 79  ? 0.895   26.639  -55.566 1.00 53.51  ? 73  LEU L N   1 
ATOM   2234 C CA  . LEU B 2 79  ? 1.499   27.467  -54.530 1.00 39.40  ? 73  LEU L CA  1 
ATOM   2235 C C   . LEU B 2 79  ? 1.875   28.812  -55.134 1.00 40.71  ? 73  LEU L C   1 
ATOM   2236 O O   . LEU B 2 79  ? 2.575   28.865  -56.151 1.00 31.54  ? 73  LEU L O   1 
ATOM   2237 C CB  . LEU B 2 79  ? 2.735   26.793  -53.933 1.00 31.96  ? 73  LEU L CB  1 
ATOM   2238 C CG  . LEU B 2 79  ? 3.587   27.674  -53.015 1.00 32.03  ? 73  LEU L CG  1 
ATOM   2239 C CD1 . LEU B 2 79  ? 2.811   28.053  -51.767 1.00 30.50  ? 73  LEU L CD1 1 
ATOM   2240 C CD2 . LEU B 2 79  ? 4.895   26.986  -52.653 1.00 44.20  ? 73  LEU L CD2 1 
ATOM   2241 N N   . THR B 2 80  ? 1.414   29.893  -54.510 1.00 36.37  ? 74  THR L N   1 
ATOM   2242 C CA  . THR B 2 80  ? 1.606   31.241  -55.029 1.00 38.36  ? 74  THR L CA  1 
ATOM   2243 C C   . THR B 2 80  ? 2.355   32.090  -54.012 1.00 48.31  ? 74  THR L C   1 
ATOM   2244 O O   . THR B 2 80  ? 1.976   32.141  -52.837 1.00 46.18  ? 74  THR L O   1 
ATOM   2245 C CB  . THR B 2 80  ? 0.263   31.895  -55.375 1.00 46.10  ? 74  THR L CB  1 
ATOM   2246 O OG1 . THR B 2 80  ? -0.333  31.211  -56.484 1.00 61.51  ? 74  THR L OG1 1 
ATOM   2247 C CG2 . THR B 2 80  ? 0.455   33.361  -55.735 1.00 48.35  ? 74  THR L CG2 1 
ATOM   2248 N N   . ILE B 2 81  ? 3.415   32.752  -54.469 1.00 47.43  ? 75  ILE L N   1 
ATOM   2249 C CA  . ILE B 2 81  ? 4.136   33.753  -53.691 1.00 46.97  ? 75  ILE L CA  1 
ATOM   2250 C C   . ILE B 2 81  ? 3.802   35.114  -54.283 1.00 55.14  ? 75  ILE L C   1 
ATOM   2251 O O   . ILE B 2 81  ? 4.068   35.364  -55.465 1.00 53.91  ? 75  ILE L O   1 
ATOM   2252 C CB  . ILE B 2 81  ? 5.650   33.493  -53.697 1.00 41.06  ? 75  ILE L CB  1 
ATOM   2253 C CG1 . ILE B 2 81  ? 5.998   32.371  -52.717 1.00 40.28  ? 75  ILE L CG1 1 
ATOM   2254 C CG2 . ILE B 2 81  ? 6.414   34.763  -53.361 1.00 55.03  ? 75  ILE L CG2 1 
ATOM   2255 C CD1 . ILE B 2 81  ? 7.393   31.820  -52.895 1.00 32.94  ? 75  ILE L CD1 1 
ATOM   2256 N N   . SER B 2 82  ? 3.212   35.992  -53.469 1.00 62.76  ? 76  SER L N   1 
ATOM   2257 C CA  . SER B 2 82  ? 2.704   37.259  -53.989 1.00 60.40  ? 76  SER L CA  1 
ATOM   2258 C C   . SER B 2 82  ? 3.843   38.200  -54.365 1.00 58.60  ? 76  SER L C   1 
ATOM   2259 O O   . SER B 2 82  ? 4.011   38.554  -55.537 1.00 56.29  ? 76  SER L O   1 
ATOM   2260 C CB  . SER B 2 82  ? 1.777   37.913  -52.961 1.00 50.50  ? 76  SER L CB  1 
ATOM   2261 O OG  . SER B 2 82  ? 0.620   37.125  -52.748 1.00 69.21  ? 76  SER L OG  1 
ATOM   2262 N N   . SER B 2 83  ? 4.642   38.609  -53.385 1.00 54.10  ? 77  SER L N   1 
ATOM   2263 C CA  . SER B 2 83  ? 5.786   39.488  -53.615 1.00 58.32  ? 77  SER L CA  1 
ATOM   2264 C C   . SER B 2 83  ? 7.045   38.690  -53.298 1.00 64.77  ? 77  SER L C   1 
ATOM   2265 O O   . SER B 2 83  ? 7.418   38.535  -52.131 1.00 55.74  ? 77  SER L O   1 
ATOM   2266 C CB  . SER B 2 83  ? 5.697   40.754  -52.768 1.00 60.43  ? 77  SER L CB  1 
ATOM   2267 O OG  . SER B 2 83  ? 6.200   40.531  -51.462 1.00 77.47  ? 77  SER L OG  1 
ATOM   2268 N N   . LEU B 2 84  ? 7.691   38.181  -54.341 1.00 58.25  ? 78  LEU L N   1 
ATOM   2269 C CA  . LEU B 2 84  ? 8.891   37.377  -54.163 1.00 51.51  ? 78  LEU L CA  1 
ATOM   2270 C C   . LEU B 2 84  ? 10.007  38.229  -53.575 1.00 57.91  ? 78  LEU L C   1 
ATOM   2271 O O   . LEU B 2 84  ? 10.454  39.200  -54.194 1.00 67.66  ? 78  LEU L O   1 
ATOM   2272 C CB  . LEU B 2 84  ? 9.311   36.775  -55.504 1.00 59.73  ? 78  LEU L CB  1 
ATOM   2273 C CG  . LEU B 2 84  ? 10.262  35.573  -55.545 1.00 44.93  ? 78  LEU L CG  1 
ATOM   2274 C CD1 . LEU B 2 84  ? 11.699  35.989  -55.324 1.00 45.74  ? 78  LEU L CD1 1 
ATOM   2275 C CD2 . LEU B 2 84  ? 9.849   34.507  -54.545 1.00 42.65  ? 78  LEU L CD2 1 
ATOM   2276 N N   . GLN B 2 85  ? 10.448  37.872  -52.375 1.00 58.44  ? 79  GLN L N   1 
ATOM   2277 C CA  . GLN B 2 85  ? 11.594  38.504  -51.744 1.00 54.60  ? 79  GLN L CA  1 
ATOM   2278 C C   . GLN B 2 85  ? 12.836  37.645  -51.951 1.00 48.50  ? 79  GLN L C   1 
ATOM   2279 O O   . GLN B 2 85  ? 12.752  36.456  -52.271 1.00 50.82  ? 79  GLN L O   1 
ATOM   2280 C CB  . GLN B 2 85  ? 11.345  38.728  -50.250 1.00 53.44  ? 79  GLN L CB  1 
ATOM   2281 C CG  . GLN B 2 85  ? 10.195  39.677  -49.949 1.00 56.35  ? 79  GLN L CG  1 
ATOM   2282 C CD  . GLN B 2 85  ? 10.145  40.090  -48.490 1.00 60.01  ? 79  GLN L CD  1 
ATOM   2283 O OE1 . GLN B 2 85  ? 11.133  39.970  -47.764 1.00 65.62  ? 79  GLN L OE1 1 
ATOM   2284 N NE2 . GLN B 2 85  ? 8.991   40.579  -48.052 1.00 53.56  ? 79  GLN L NE2 1 
ATOM   2285 N N   . ALA B 2 86  ? 14.002  38.270  -51.771 1.00 62.45  ? 80  ALA L N   1 
ATOM   2286 C CA  . ALA B 2 86  ? 15.263  37.567  -51.976 1.00 62.45  ? 80  ALA L CA  1 
ATOM   2287 C C   . ALA B 2 86  ? 15.443  36.407  -51.007 1.00 53.41  ? 80  ALA L C   1 
ATOM   2288 O O   . ALA B 2 86  ? 16.188  35.469  -51.309 1.00 47.97  ? 80  ALA L O   1 
ATOM   2289 C CB  . ALA B 2 86  ? 16.434  38.541  -51.849 1.00 58.94  ? 80  ALA L CB  1 
ATOM   2290 N N   . GLU B 2 87  ? 14.772  36.446  -49.858 1.00 43.51  ? 81  GLU L N   1 
ATOM   2291 C CA  . GLU B 2 87  ? 14.846  35.380  -48.868 1.00 43.46  ? 81  GLU L CA  1 
ATOM   2292 C C   . GLU B 2 87  ? 13.976  34.179  -49.220 1.00 55.20  ? 81  GLU L C   1 
ATOM   2293 O O   . GLU B 2 87  ? 14.011  33.178  -48.496 1.00 53.20  ? 81  GLU L O   1 
ATOM   2294 C CB  . GLU B 2 87  ? 14.448  35.919  -47.493 1.00 44.89  ? 81  GLU L CB  1 
ATOM   2295 C CG  . GLU B 2 87  ? 13.151  36.710  -47.503 1.00 62.94  ? 81  GLU L CG  1 
ATOM   2296 C CD  . GLU B 2 87  ? 12.540  36.854  -46.124 1.00 65.72  ? 81  GLU L CD  1 
ATOM   2297 O OE1 . GLU B 2 87  ? 13.295  36.845  -45.130 1.00 63.57  ? 81  GLU L OE1 1 
ATOM   2298 O OE2 . GLU B 2 87  ? 11.299  36.967  -46.036 1.00 79.26  ? 81  GLU L OE2 1 
ATOM   2299 N N   . ASP B 2 88  ? 13.197  34.253  -50.296 1.00 57.51  ? 82  ASP L N   1 
ATOM   2300 C CA  . ASP B 2 88  ? 12.342  33.152  -50.720 1.00 42.23  ? 82  ASP L CA  1 
ATOM   2301 C C   . ASP B 2 88  ? 13.017  32.230  -51.728 1.00 41.97  ? 82  ASP L C   1 
ATOM   2302 O O   . ASP B 2 88  ? 12.362  31.320  -52.247 1.00 43.63  ? 82  ASP L O   1 
ATOM   2303 C CB  . ASP B 2 88  ? 11.041  33.697  -51.315 1.00 46.75  ? 82  ASP L CB  1 
ATOM   2304 C CG  . ASP B 2 88  ? 10.343  34.680  -50.394 1.00 53.92  ? 82  ASP L CG  1 
ATOM   2305 O OD1 . ASP B 2 88  ? 10.451  34.519  -49.160 1.00 47.22  ? 82  ASP L OD1 1 
ATOM   2306 O OD2 . ASP B 2 88  ? 9.689   35.615  -50.903 1.00 55.92  ? 82  ASP L OD2 1 
ATOM   2307 N N   . VAL B 2 89  ? 14.298  32.445  -52.020 1.00 48.64  ? 83  VAL L N   1 
ATOM   2308 C CA  . VAL B 2 89  ? 15.029  31.600  -52.960 1.00 40.59  ? 83  VAL L CA  1 
ATOM   2309 C C   . VAL B 2 89  ? 15.294  30.257  -52.290 1.00 41.18  ? 83  VAL L C   1 
ATOM   2310 O O   . VAL B 2 89  ? 16.062  30.176  -51.327 1.00 47.65  ? 83  VAL L O   1 
ATOM   2311 C CB  . VAL B 2 89  ? 16.337  32.258  -53.407 1.00 37.49  ? 83  VAL L CB  1 
ATOM   2312 C CG1 . VAL B 2 89  ? 17.128  31.319  -54.305 1.00 29.15  ? 83  VAL L CG1 1 
ATOM   2313 C CG2 . VAL B 2 89  ? 16.045  33.547  -54.115 1.00 51.19  ? 83  VAL L CG2 1 
ATOM   2314 N N   . ALA B 2 90  ? 14.672  29.206  -52.802 1.00 46.48  ? 84  ALA L N   1 
ATOM   2315 C CA  . ALA B 2 90  ? 14.830  27.858  -52.266 1.00 46.72  ? 84  ALA L CA  1 
ATOM   2316 C C   . ALA B 2 90  ? 14.234  26.884  -53.275 1.00 40.15  ? 84  ALA L C   1 
ATOM   2317 O O   . ALA B 2 90  ? 13.889  27.262  -54.401 1.00 41.85  ? 84  ALA L O   1 
ATOM   2318 C CB  . ALA B 2 90  ? 14.174  27.727  -50.890 1.00 38.61  ? 84  ALA L CB  1 
ATOM   2319 N N   . VAL B 2 91  ? 14.123  25.623  -52.871 1.00 38.60  ? 85  VAL L N   1 
ATOM   2320 C CA  . VAL B 2 91  ? 13.433  24.593  -53.637 1.00 37.30  ? 85  VAL L CA  1 
ATOM   2321 C C   . VAL B 2 91  ? 12.166  24.226  -52.880 1.00 37.72  ? 85  VAL L C   1 
ATOM   2322 O O   . VAL B 2 91  ? 12.218  23.927  -51.680 1.00 35.74  ? 85  VAL L O   1 
ATOM   2323 C CB  . VAL B 2 91  ? 14.322  23.359  -53.863 1.00 37.07  ? 85  VAL L CB  1 
ATOM   2324 C CG1 . VAL B 2 91  ? 13.508  22.227  -54.466 1.00 35.43  ? 85  VAL L CG1 1 
ATOM   2325 C CG2 . VAL B 2 91  ? 15.494  23.714  -54.763 1.00 33.09  ? 85  VAL L CG2 1 
ATOM   2326 N N   . TYR B 2 92  ? 11.033  24.260  -53.573 1.00 43.19  ? 86  TYR L N   1 
ATOM   2327 C CA  . TYR B 2 92  ? 9.728   24.048  -52.964 1.00 36.10  ? 86  TYR L CA  1 
ATOM   2328 C C   . TYR B 2 92  ? 9.182   22.684  -53.364 1.00 32.39  ? 86  TYR L C   1 
ATOM   2329 O O   . TYR B 2 92  ? 9.166   22.340  -54.550 1.00 42.12  ? 86  TYR L O   1 
ATOM   2330 C CB  . TYR B 2 92  ? 8.754   25.155  -53.370 1.00 34.18  ? 86  TYR L CB  1 
ATOM   2331 C CG  . TYR B 2 92  ? 9.139   26.515  -52.833 1.00 42.07  ? 86  TYR L CG  1 
ATOM   2332 C CD1 . TYR B 2 92  ? 10.030  27.329  -53.520 1.00 37.11  ? 86  TYR L CD1 1 
ATOM   2333 C CD2 . TYR B 2 92  ? 8.618   26.980  -51.634 1.00 38.53  ? 86  TYR L CD2 1 
ATOM   2334 C CE1 . TYR B 2 92  ? 10.388  28.570  -53.029 1.00 40.38  ? 86  TYR L CE1 1 
ATOM   2335 C CE2 . TYR B 2 92  ? 8.970   28.219  -51.136 1.00 34.73  ? 86  TYR L CE2 1 
ATOM   2336 C CZ  . TYR B 2 92  ? 9.854   29.010  -51.836 1.00 45.81  ? 86  TYR L CZ  1 
ATOM   2337 O OH  . TYR B 2 92  ? 10.206  30.246  -51.343 1.00 50.07  ? 86  TYR L OH  1 
ATOM   2338 N N   . TYR B 2 93  ? 8.737   21.917  -52.372 1.00 26.22  ? 87  TYR L N   1 
ATOM   2339 C CA  . TYR B 2 93  ? 8.187   20.586  -52.578 1.00 40.86  ? 87  TYR L CA  1 
ATOM   2340 C C   . TYR B 2 93  ? 6.726   20.560  -52.153 1.00 34.12  ? 87  TYR L C   1 
ATOM   2341 O O   . TYR B 2 93  ? 6.351   21.171  -51.148 1.00 32.92  ? 87  TYR L O   1 
ATOM   2342 C CB  . TYR B 2 93  ? 8.958   19.527  -51.776 1.00 40.53  ? 87  TYR L CB  1 
ATOM   2343 C CG  . TYR B 2 93  ? 10.409  19.348  -52.163 1.00 35.62  ? 87  TYR L CG  1 
ATOM   2344 C CD1 . TYR B 2 93  ? 10.776  18.456  -53.162 1.00 42.12  ? 87  TYR L CD1 1 
ATOM   2345 C CD2 . TYR B 2 93  ? 11.414  20.049  -51.510 1.00 33.58  ? 87  TYR L CD2 1 
ATOM   2346 C CE1 . TYR B 2 93  ? 12.101  18.279  -53.513 1.00 35.21  ? 87  TYR L CE1 1 
ATOM   2347 C CE2 . TYR B 2 93  ? 12.743  19.878  -51.852 1.00 44.78  ? 87  TYR L CE2 1 
ATOM   2348 C CZ  . TYR B 2 93  ? 13.080  18.992  -52.855 1.00 45.87  ? 87  TYR L CZ  1 
ATOM   2349 O OH  . TYR B 2 93  ? 14.402  18.819  -53.200 1.00 47.26  ? 87  TYR L OH  1 
ATOM   2350 N N   . CYS B 2 94  ? 5.903   19.853  -52.920 1.00 40.93  ? 88  CYS L N   1 
ATOM   2351 C CA  . CYS B 2 94  ? 4.566   19.488  -52.479 1.00 40.50  ? 88  CYS L CA  1 
ATOM   2352 C C   . CYS B 2 94  ? 4.562   18.022  -52.072 1.00 31.07  ? 88  CYS L C   1 
ATOM   2353 O O   . CYS B 2 94  ? 5.258   17.196  -52.670 1.00 40.91  ? 88  CYS L O   1 
ATOM   2354 C CB  . CYS B 2 94  ? 3.514   19.747  -53.562 1.00 43.11  ? 88  CYS L CB  1 
ATOM   2355 S SG  . CYS B 2 94  ? 3.673   18.796  -55.095 1.00 60.87  ? 88  CYS L SG  1 
ATOM   2356 N N   . GLN B 2 95  ? 3.791   17.707  -51.037 1.00 33.90  ? 89  GLN L N   1 
ATOM   2357 C CA  . GLN B 2 95  ? 3.794   16.376  -50.452 1.00 38.72  ? 89  GLN L CA  1 
ATOM   2358 C C   . GLN B 2 95  ? 2.385   16.018  -50.009 1.00 41.25  ? 89  GLN L C   1 
ATOM   2359 O O   . GLN B 2 95  ? 1.651   16.872  -49.503 1.00 38.60  ? 89  GLN L O   1 
ATOM   2360 C CB  . GLN B 2 95  ? 4.765   16.305  -49.268 1.00 34.36  ? 89  GLN L CB  1 
ATOM   2361 C CG  . GLN B 2 95  ? 4.795   14.971  -48.544 1.00 39.35  ? 89  GLN L CG  1 
ATOM   2362 C CD  . GLN B 2 95  ? 4.236   15.065  -47.143 1.00 31.13  ? 89  GLN L CD  1 
ATOM   2363 O OE1 . GLN B 2 95  ? 3.406   15.926  -46.852 1.00 36.45  ? 89  GLN L OE1 1 
ATOM   2364 N NE2 . GLN B 2 95  ? 4.693   14.185  -46.261 1.00 39.91  ? 89  GLN L NE2 1 
ATOM   2365 N N   . GLN B 2 96  ? 2.011   14.758  -50.206 1.00 38.08  ? 90  GLN L N   1 
ATOM   2366 C CA  . GLN B 2 96  ? 0.706   14.257  -49.802 1.00 39.13  ? 90  GLN L CA  1 
ATOM   2367 C C   . GLN B 2 96  ? 0.864   13.383  -48.566 1.00 40.75  ? 90  GLN L C   1 
ATOM   2368 O O   . GLN B 2 96  ? 1.776   12.550  -48.496 1.00 44.27  ? 90  GLN L O   1 
ATOM   2369 C CB  . GLN B 2 96  ? 0.031   13.478  -50.937 1.00 32.30  ? 90  GLN L CB  1 
ATOM   2370 C CG  . GLN B 2 96  ? 0.719   12.179  -51.345 1.00 36.54  ? 90  GLN L CG  1 
ATOM   2371 C CD  . GLN B 2 96  ? 0.215   10.974  -50.567 1.00 38.43  ? 90  GLN L CD  1 
ATOM   2372 O OE1 . GLN B 2 96  ? -0.853  11.016  -49.956 1.00 34.53  ? 90  GLN L OE1 1 
ATOM   2373 N NE2 . GLN B 2 96  ? 0.988   9.894   -50.582 1.00 36.37  ? 90  GLN L NE2 1 
ATOM   2374 N N   . TYR B 2 97  ? -0.003  13.601  -47.582 1.00 32.92  ? 91  TYR L N   1 
ATOM   2375 C CA  . TYR B 2 97  ? -0.118  12.726  -46.424 1.00 42.86  ? 91  TYR L CA  1 
ATOM   2376 C C   . TYR B 2 97  ? -1.497  12.077  -46.388 1.00 37.70  ? 91  TYR L C   1 
ATOM   2377 O O   . TYR B 2 97  ? -2.004  11.719  -45.325 1.00 32.03  ? 91  TYR L O   1 
ATOM   2378 C CB  . TYR B 2 97  ? 0.179   13.483  -45.127 1.00 40.83  ? 91  TYR L CB  1 
ATOM   2379 C CG  . TYR B 2 97  ? -0.461  14.852  -45.014 1.00 39.65  ? 91  TYR L CG  1 
ATOM   2380 C CD1 . TYR B 2 97  ? 0.138   15.974  -45.576 1.00 38.13  ? 91  TYR L CD1 1 
ATOM   2381 C CD2 . TYR B 2 97  ? -1.650  15.027  -44.322 1.00 40.73  ? 91  TYR L CD2 1 
ATOM   2382 C CE1 . TYR B 2 97  ? -0.442  17.226  -45.466 1.00 40.53  ? 91  TYR L CE1 1 
ATOM   2383 C CE2 . TYR B 2 97  ? -2.236  16.274  -44.207 1.00 36.06  ? 91  TYR L CE2 1 
ATOM   2384 C CZ  . TYR B 2 97  ? -1.629  17.369  -44.780 1.00 35.13  ? 91  TYR L CZ  1 
ATOM   2385 O OH  . TYR B 2 97  ? -2.212  18.611  -44.663 1.00 29.67  ? 91  TYR L OH  1 
ATOM   2386 N N   . TYR B 2 98  ? -2.107  11.926  -47.566 1.00 40.15  ? 92  TYR L N   1 
ATOM   2387 C CA  . TYR B 2 98  ? -3.429  11.317  -47.671 1.00 39.04  ? 92  TYR L CA  1 
ATOM   2388 C C   . TYR B 2 98  ? -3.380  9.823   -47.374 1.00 33.83  ? 92  TYR L C   1 
ATOM   2389 O O   . TYR B 2 98  ? -4.292  9.280   -46.741 1.00 44.02  ? 92  TYR L O   1 
ATOM   2390 C CB  . TYR B 2 98  ? -3.994  11.580  -49.068 1.00 43.03  ? 92  TYR L CB  1 
ATOM   2391 C CG  . TYR B 2 98  ? -5.341  10.958  -49.365 1.00 49.89  ? 92  TYR L CG  1 
ATOM   2392 C CD1 . TYR B 2 98  ? -6.519  11.635  -49.074 1.00 44.67  ? 92  TYR L CD1 1 
ATOM   2393 C CD2 . TYR B 2 98  ? -5.435  9.710   -49.968 1.00 38.84  ? 92  TYR L CD2 1 
ATOM   2394 C CE1 . TYR B 2 98  ? -7.751  11.080  -49.359 1.00 48.97  ? 92  TYR L CE1 1 
ATOM   2395 C CE2 . TYR B 2 98  ? -6.663  9.146   -50.256 1.00 40.86  ? 92  TYR L CE2 1 
ATOM   2396 C CZ  . TYR B 2 98  ? -7.817  9.835   -49.949 1.00 55.42  ? 92  TYR L CZ  1 
ATOM   2397 O OH  . TYR B 2 98  ? -9.041  9.275   -50.234 1.00 51.96  ? 92  TYR L OH  1 
ATOM   2398 N N   . SER B 2 99  ? -2.330  9.142   -47.828 1.00 33.39  ? 93  SER L N   1 
ATOM   2399 C CA  . SER B 2 99  ? -2.210  7.706   -47.632 1.00 30.99  ? 93  SER L CA  1 
ATOM   2400 C C   . SER B 2 99  ? -0.740  7.317   -47.632 1.00 40.54  ? 93  SER L C   1 
ATOM   2401 O O   . SER B 2 99  ? 0.071   7.903   -48.357 1.00 41.60  ? 93  SER L O   1 
ATOM   2402 C CB  . SER B 2 99  ? -2.958  6.925   -48.719 1.00 37.95  ? 93  SER L CB  1 
ATOM   2403 O OG  . SER B 2 99  ? -2.389  7.158   -49.998 1.00 24.31  ? 93  SER L OG  1 
ATOM   2404 N N   . THR B 2 100 ? -0.406  6.324   -46.816 1.00 32.46  ? 94  THR L N   1 
ATOM   2405 C CA  . THR B 2 100 ? 0.951   5.797   -46.816 1.00 38.18  ? 94  THR L CA  1 
ATOM   2406 C C   . THR B 2 100 ? 1.204   5.023   -48.109 1.00 37.56  ? 94  THR L C   1 
ATOM   2407 O O   . THR B 2 100 ? 0.304   4.345   -48.614 1.00 45.64  ? 94  THR L O   1 
ATOM   2408 C CB  . THR B 2 100 ? 1.184   4.887   -45.610 1.00 24.50  ? 94  THR L CB  1 
ATOM   2409 O OG1 . THR B 2 100 ? 0.330   3.740   -45.701 1.00 48.49  ? 94  THR L OG1 1 
ATOM   2410 C CG2 . THR B 2 100 ? 0.885   5.631   -44.316 1.00 30.52  ? 94  THR L CG2 1 
ATOM   2411 N N   . PRO B 2 101 ? 2.414   5.106   -48.673 1.00 42.18  ? 95  PRO L N   1 
ATOM   2412 C CA  . PRO B 2 101 ? 3.571   5.880   -48.208 1.00 45.33  ? 95  PRO L CA  1 
ATOM   2413 C C   . PRO B 2 101 ? 3.466   7.357   -48.570 1.00 41.70  ? 95  PRO L C   1 
ATOM   2414 O O   . PRO B 2 101 ? 2.793   7.713   -49.534 1.00 39.26  ? 95  PRO L O   1 
ATOM   2415 C CB  . PRO B 2 101 ? 4.736   5.199   -48.933 1.00 36.65  ? 95  PRO L CB  1 
ATOM   2416 C CG  . PRO B 2 101 ? 4.133   4.795   -50.249 1.00 27.12  ? 95  PRO L CG  1 
ATOM   2417 C CD  . PRO B 2 101 ? 2.712   4.383   -49.924 1.00 29.63  ? 95  PRO L CD  1 
ATOM   2418 N N   . TYR B 2 102 ? 4.114   8.240   -47.816 1.00 35.10  ? 96  TYR L N   1 
ATOM   2419 C CA  . TYR B 2 102 ? 4.178   9.640   -48.207 1.00 30.59  ? 96  TYR L CA  1 
ATOM   2420 C C   . TYR B 2 102 ? 5.036   9.790   -49.456 1.00 34.53  ? 96  TYR L C   1 
ATOM   2421 O O   . TYR B 2 102 ? 6.048   9.103   -49.622 1.00 34.62  ? 96  TYR L O   1 
ATOM   2422 C CB  . TYR B 2 102 ? 4.753   10.495  -47.079 1.00 35.59  ? 96  TYR L CB  1 
ATOM   2423 C CG  . TYR B 2 102 ? 3.915   10.530  -45.821 1.00 35.37  ? 96  TYR L CG  1 
ATOM   2424 C CD1 . TYR B 2 102 ? 2.564   10.210  -45.848 1.00 35.93  ? 96  TYR L CD1 1 
ATOM   2425 C CD2 . TYR B 2 102 ? 4.479   10.889  -44.603 1.00 30.47  ? 96  TYR L CD2 1 
ATOM   2426 C CE1 . TYR B 2 102 ? 1.799   10.242  -44.696 1.00 30.98  ? 96  TYR L CE1 1 
ATOM   2427 C CE2 . TYR B 2 102 ? 3.724   10.925  -43.448 1.00 32.95  ? 96  TYR L CE2 1 
ATOM   2428 C CZ  . TYR B 2 102 ? 2.385   10.601  -43.498 1.00 40.11  ? 96  TYR L CZ  1 
ATOM   2429 O OH  . TYR B 2 102 ? 1.630   10.635  -42.348 1.00 26.63  ? 96  TYR L OH  1 
ATOM   2430 N N   . THR B 2 103 ? 4.625   10.690  -50.342 1.00 32.56  ? 97  THR L N   1 
ATOM   2431 C CA  . THR B 2 103 ? 5.359   10.959  -51.567 1.00 38.24  ? 97  THR L CA  1 
ATOM   2432 C C   . THR B 2 103 ? 5.497   12.461  -51.754 1.00 39.01  ? 97  THR L C   1 
ATOM   2433 O O   . THR B 2 103 ? 4.567   13.221  -51.467 1.00 32.45  ? 97  THR L O   1 
ATOM   2434 C CB  . THR B 2 103 ? 4.665   10.341  -52.788 1.00 37.60  ? 97  THR L CB  1 
ATOM   2435 O OG1 . THR B 2 103 ? 3.313   10.810  -52.860 1.00 36.33  ? 97  THR L OG1 1 
ATOM   2436 C CG2 . THR B 2 103 ? 4.666   8.821   -52.692 1.00 32.73  ? 97  THR L CG2 1 
ATOM   2437 N N   . PHE B 2 104 ? 6.665   12.881  -52.226 1.00 41.47  ? 98  PHE L N   1 
ATOM   2438 C CA  . PHE B 2 104 ? 6.945   14.275  -52.524 1.00 28.44  ? 98  PHE L CA  1 
ATOM   2439 C C   . PHE B 2 104 ? 6.916   14.512  -54.029 1.00 33.42  ? 98  PHE L C   1 
ATOM   2440 O O   . PHE B 2 104 ? 6.982   13.578  -54.833 1.00 42.65  ? 98  PHE L O   1 
ATOM   2441 C CB  . PHE B 2 104 ? 8.311   14.690  -51.971 1.00 33.18  ? 98  PHE L CB  1 
ATOM   2442 C CG  . PHE B 2 104 ? 8.403   14.656  -50.472 1.00 36.13  ? 98  PHE L CG  1 
ATOM   2443 C CD1 . PHE B 2 104 ? 8.787   13.500  -49.813 1.00 29.75  ? 98  PHE L CD1 1 
ATOM   2444 C CD2 . PHE B 2 104 ? 8.128   15.789  -49.724 1.00 33.88  ? 98  PHE L CD2 1 
ATOM   2445 C CE1 . PHE B 2 104 ? 8.881   13.471  -48.434 1.00 32.76  ? 98  PHE L CE1 1 
ATOM   2446 C CE2 . PHE B 2 104 ? 8.219   15.765  -48.345 1.00 34.10  ? 98  PHE L CE2 1 
ATOM   2447 C CZ  . PHE B 2 104 ? 8.595   14.605  -47.699 1.00 41.53  ? 98  PHE L CZ  1 
ATOM   2448 N N   . GLY B 2 105 ? 6.808   15.784  -54.403 1.00 32.04  ? 99  GLY L N   1 
ATOM   2449 C CA  . GLY B 2 105 ? 7.060   16.173  -55.771 1.00 38.49  ? 99  GLY L CA  1 
ATOM   2450 C C   . GLY B 2 105 ? 8.547   16.191  -56.069 1.00 39.38  ? 99  GLY L C   1 
ATOM   2451 O O   . GLY B 2 105 ? 9.390   16.085  -55.178 1.00 44.32  ? 99  GLY L O   1 
ATOM   2452 N N   . GLN B 2 106 ? 8.877   16.323  -57.355 1.00 31.63  ? 100 GLN L N   1 
ATOM   2453 C CA  . GLN B 2 106 ? 10.284  16.341  -57.736 1.00 32.05  ? 100 GLN L CA  1 
ATOM   2454 C C   . GLN B 2 106 ? 10.990  17.624  -57.315 1.00 42.47  ? 100 GLN L C   1 
ATOM   2455 O O   . GLN B 2 106 ? 12.225  17.664  -57.333 1.00 38.95  ? 100 GLN L O   1 
ATOM   2456 C CB  . GLN B 2 106 ? 10.436  16.136  -59.246 1.00 27.53  ? 100 GLN L CB  1 
ATOM   2457 C CG  . GLN B 2 106 ? 10.160  17.367  -60.095 1.00 39.73  ? 100 GLN L CG  1 
ATOM   2458 C CD  . GLN B 2 106 ? 8.690   17.546  -60.415 1.00 43.39  ? 100 GLN L CD  1 
ATOM   2459 O OE1 . GLN B 2 106 ? 7.819   17.098  -59.669 1.00 42.09  ? 100 GLN L OE1 1 
ATOM   2460 N NE2 . GLN B 2 106 ? 8.406   18.200  -61.536 1.00 42.75  ? 100 GLN L NE2 1 
ATOM   2461 N N   . GLY B 2 107 ? 10.252  18.655  -56.939 1.00 41.02  ? 101 GLY L N   1 
ATOM   2462 C CA  . GLY B 2 107 ? 10.839  19.894  -56.473 1.00 32.54  ? 101 GLY L CA  1 
ATOM   2463 C C   . GLY B 2 107 ? 10.887  20.955  -57.558 1.00 30.33  ? 101 GLY L C   1 
ATOM   2464 O O   . GLY B 2 107 ? 11.060  20.665  -58.747 1.00 29.54  ? 101 GLY L O   1 
ATOM   2465 N N   . THR B 2 108 ? 10.734  22.211  -57.141 1.00 31.69  ? 102 THR L N   1 
ATOM   2466 C CA  . THR B 2 108 ? 10.799  23.356  -58.039 1.00 33.41  ? 102 THR L CA  1 
ATOM   2467 C C   . THR B 2 108 ? 11.824  24.336  -57.494 1.00 41.44  ? 102 THR L C   1 
ATOM   2468 O O   . THR B 2 108 ? 11.721  24.765  -56.340 1.00 46.61  ? 102 THR L O   1 
ATOM   2469 C CB  . THR B 2 108 ? 9.432   24.034  -58.183 1.00 38.66  ? 102 THR L CB  1 
ATOM   2470 O OG1 . THR B 2 108 ? 8.501   23.116  -58.769 1.00 41.12  ? 102 THR L OG1 1 
ATOM   2471 C CG2 . THR B 2 108 ? 9.537   25.276  -59.060 1.00 35.66  ? 102 THR L CG2 1 
ATOM   2472 N N   . LYS B 2 109 ? 12.803  24.691  -58.323 1.00 46.26  ? 103 LYS L N   1 
ATOM   2473 C CA  . LYS B 2 109 ? 13.838  25.646  -57.948 1.00 38.75  ? 103 LYS L CA  1 
ATOM   2474 C C   . LYS B 2 109 ? 13.379  27.056  -58.300 1.00 41.47  ? 103 LYS L C   1 
ATOM   2475 O O   . LYS B 2 109 ? 12.991  27.324  -59.443 1.00 52.58  ? 103 LYS L O   1 
ATOM   2476 C CB  . LYS B 2 109 ? 15.156  25.315  -58.650 1.00 49.11  ? 103 LYS L CB  1 
ATOM   2477 C CG  . LYS B 2 109 ? 16.243  26.359  -58.458 1.00 52.36  ? 103 LYS L CG  1 
ATOM   2478 C CD  . LYS B 2 109 ? 16.605  26.523  -56.994 1.00 57.68  ? 103 LYS L CD  1 
ATOM   2479 C CE  . LYS B 2 109 ? 17.621  27.636  -56.808 1.00 51.30  ? 103 LYS L CE  1 
ATOM   2480 N NZ  . LYS B 2 109 ? 17.948  27.848  -55.372 1.00 52.06  ? 103 LYS L NZ  1 
ATOM   2481 N N   . VAL B 2 110 ? 13.421  27.950  -57.317 1.00 35.84  ? 104 VAL L N   1 
ATOM   2482 C CA  . VAL B 2 110 ? 13.004  29.337  -57.485 1.00 53.10  ? 104 VAL L CA  1 
ATOM   2483 C C   . VAL B 2 110 ? 14.233  30.226  -57.344 1.00 47.12  ? 104 VAL L C   1 
ATOM   2484 O O   . VAL B 2 110 ? 14.920  30.194  -56.315 1.00 42.10  ? 104 VAL L O   1 
ATOM   2485 C CB  . VAL B 2 110 ? 11.919  29.727  -56.469 1.00 47.25  ? 104 VAL L CB  1 
ATOM   2486 C CG1 . VAL B 2 110 ? 11.768  31.238  -56.404 1.00 32.14  ? 104 VAL L CG1 1 
ATOM   2487 C CG2 . VAL B 2 110 ? 10.596  29.072  -56.836 1.00 41.90  ? 104 VAL L CG2 1 
ATOM   2488 N N   . GLU B 2 111 ? 14.501  31.023  -58.374 1.00 38.69  ? 105 GLU L N   1 
ATOM   2489 C CA  . GLU B 2 111 ? 15.609  31.965  -58.404 1.00 40.39  ? 105 GLU L CA  1 
ATOM   2490 C C   . GLU B 2 111 ? 15.072  33.374  -58.612 1.00 41.86  ? 105 GLU L C   1 
ATOM   2491 O O   . GLU B 2 111 ? 13.913  33.573  -58.984 1.00 47.79  ? 105 GLU L O   1 
ATOM   2492 C CB  . GLU B 2 111 ? 16.603  31.615  -59.517 1.00 40.68  ? 105 GLU L CB  1 
ATOM   2493 C CG  . GLU B 2 111 ? 16.006  31.697  -60.918 1.00 63.25  ? 105 GLU L CG  1 
ATOM   2494 C CD  . GLU B 2 111 ? 17.057  31.663  -62.015 1.00 66.48  ? 105 GLU L CD  1 
ATOM   2495 O OE1 . GLU B 2 111 ? 18.059  30.932  -61.862 1.00 65.42  ? 105 GLU L OE1 1 
ATOM   2496 O OE2 . GLU B 2 111 ? 16.884  32.375  -63.027 1.00 64.99  ? 105 GLU L OE2 1 
ATOM   2497 N N   . ILE B 2 112 ? 15.938  34.356  -58.378 1.00 38.48  ? 106 ILE L N   1 
ATOM   2498 C CA  . ILE B 2 112 ? 15.624  35.756  -58.644 1.00 41.30  ? 106 ILE L CA  1 
ATOM   2499 C C   . ILE B 2 112 ? 15.942  36.043  -60.101 1.00 38.78  ? 106 ILE L C   1 
ATOM   2500 O O   . ILE B 2 112 ? 17.096  35.916  -60.525 1.00 40.81  ? 106 ILE L O   1 
ATOM   2501 C CB  . ILE B 2 112 ? 16.428  36.698  -57.739 1.00 38.60  ? 106 ILE L CB  1 
ATOM   2502 C CG1 . ILE B 2 112 ? 16.397  36.218  -56.290 1.00 44.50  ? 106 ILE L CG1 1 
ATOM   2503 C CG2 . ILE B 2 112 ? 15.888  38.122  -57.873 1.00 52.52  ? 106 ILE L CG2 1 
ATOM   2504 C CD1 . ILE B 2 112 ? 15.121  36.595  -55.562 1.00 40.62  ? 106 ILE L CD1 1 
ATOM   2505 N N   . LYS B 2 113 ? 14.935  36.448  -60.866 1.00 39.10  ? 107 LYS L N   1 
ATOM   2506 C CA  . LYS B 2 113 ? 15.166  36.834  -62.254 1.00 38.49  ? 107 LYS L CA  1 
ATOM   2507 C C   . LYS B 2 113 ? 15.793  38.221  -62.277 1.00 52.43  ? 107 LYS L C   1 
ATOM   2508 O O   . LYS B 2 113 ? 15.099  39.232  -62.155 1.00 65.80  ? 107 LYS L O   1 
ATOM   2509 C CB  . LYS B 2 113 ? 13.865  36.811  -63.048 1.00 47.67  ? 107 LYS L CB  1 
ATOM   2510 C CG  . LYS B 2 113 ? 14.077  36.990  -64.547 1.00 42.69  ? 107 LYS L CG  1 
ATOM   2511 C CD  . LYS B 2 113 ? 12.866  37.603  -65.236 1.00 54.96  ? 107 LYS L CD  1 
ATOM   2512 C CE  . LYS B 2 113 ? 11.680  36.655  -65.259 1.00 58.24  ? 107 LYS L CE  1 
ATOM   2513 N NZ  . LYS B 2 113 ? 11.933  35.433  -66.071 1.00 59.90  ? 107 LYS L NZ  1 
ATOM   2514 N N   . ARG B 2 114 ? 17.113  38.276  -62.425 1.00 44.37  ? 108 ARG L N   1 
ATOM   2515 C CA  . ARG B 2 114 ? 17.817  39.529  -62.634 1.00 35.69  ? 108 ARG L CA  1 
ATOM   2516 C C   . ARG B 2 114 ? 18.043  39.732  -64.127 1.00 42.00  ? 108 ARG L C   1 
ATOM   2517 O O   . ARG B 2 114 ? 17.629  38.925  -64.963 1.00 38.59  ? 108 ARG L O   1 
ATOM   2518 C CB  . ARG B 2 114 ? 19.144  39.555  -61.874 1.00 43.16  ? 108 ARG L CB  1 
ATOM   2519 C CG  . ARG B 2 114 ? 20.229  38.646  -62.446 1.00 45.04  ? 108 ARG L CG  1 
ATOM   2520 C CD  . ARG B 2 114 ? 21.610  39.247  -62.224 1.00 41.21  ? 108 ARG L CD  1 
ATOM   2521 N NE  . ARG B 2 114 ? 21.867  40.352  -63.140 1.00 33.07  ? 108 ARG L NE  1 
ATOM   2522 C CZ  . ARG B 2 114 ? 22.823  41.257  -62.980 1.00 48.65  ? 108 ARG L CZ  1 
ATOM   2523 N NH1 . ARG B 2 114 ? 23.611  41.249  -61.919 1.00 47.64  ? 108 ARG L NH1 1 
ATOM   2524 N NH2 . ARG B 2 114 ? 22.992  42.192  -63.908 1.00 65.93  ? 108 ARG L NH2 1 
ATOM   2525 N N   . THR B 2 115 ? 18.715  40.824  -64.465 1.00 43.47  ? 109 THR L N   1 
ATOM   2526 C CA  . THR B 2 115 ? 18.995  41.095  -65.862 1.00 50.30  ? 109 THR L CA  1 
ATOM   2527 C C   . THR B 2 115 ? 20.184  40.266  -66.337 1.00 44.05  ? 109 THR L C   1 
ATOM   2528 O O   . THR B 2 115 ? 20.988  39.768  -65.543 1.00 36.22  ? 109 THR L O   1 
ATOM   2529 C CB  . THR B 2 115 ? 19.260  42.581  -66.084 1.00 50.60  ? 109 THR L CB  1 
ATOM   2530 O OG1 . THR B 2 115 ? 19.948  42.760  -67.328 1.00 62.29  ? 109 THR L OG1 1 
ATOM   2531 C CG2 . THR B 2 115 ? 20.101  43.147  -64.954 1.00 53.34  ? 109 THR L CG2 1 
ATOM   2532 N N   . VAL B 2 116 ? 20.273  40.113  -67.659 1.00 38.79  ? 110 VAL L N   1 
ATOM   2533 C CA  . VAL B 2 116 ? 21.339  39.323  -68.257 1.00 38.00  ? 110 VAL L CA  1 
ATOM   2534 C C   . VAL B 2 116 ? 22.686  39.949  -67.929 1.00 43.68  ? 110 VAL L C   1 
ATOM   2535 O O   . VAL B 2 116 ? 22.901  41.152  -68.126 1.00 41.52  ? 110 VAL L O   1 
ATOM   2536 C CB  . VAL B 2 116 ? 21.128  39.210  -69.773 1.00 32.57  ? 110 VAL L CB  1 
ATOM   2537 C CG1 . VAL B 2 116 ? 22.444  38.938  -70.468 1.00 34.29  ? 110 VAL L CG1 1 
ATOM   2538 C CG2 . VAL B 2 116 ? 20.124  38.111  -70.078 1.00 33.86  ? 110 VAL L CG2 1 
ATOM   2539 N N   . ALA B 2 117 ? 23.600  39.130  -67.413 1.00 39.77  ? 111 ALA L N   1 
ATOM   2540 C CA  . ALA B 2 117 ? 24.945  39.568  -67.069 1.00 39.54  ? 111 ALA L CA  1 
ATOM   2541 C C   . ALA B 2 117 ? 25.946  38.587  -67.660 1.00 43.20  ? 111 ALA L C   1 
ATOM   2542 O O   . ALA B 2 117 ? 25.912  37.394  -67.338 1.00 53.02  ? 111 ALA L O   1 
ATOM   2543 C CB  . ALA B 2 117 ? 25.119  39.675  -65.552 1.00 34.51  ? 111 ALA L CB  1 
ATOM   2544 N N   . ALA B 2 118 ? 26.831  39.088  -68.518 1.00 30.77  ? 112 ALA L N   1 
ATOM   2545 C CA  . ALA B 2 118 ? 27.833  38.238  -69.137 1.00 34.46  ? 112 ALA L CA  1 
ATOM   2546 C C   . ALA B 2 118 ? 28.882  37.811  -68.110 1.00 44.49  ? 112 ALA L C   1 
ATOM   2547 O O   . ALA B 2 118 ? 29.162  38.540  -67.154 1.00 41.12  ? 112 ALA L O   1 
ATOM   2548 C CB  . ALA B 2 118 ? 28.505  38.964  -70.299 1.00 23.72  ? 112 ALA L CB  1 
ATOM   2549 N N   . PRO B 2 119 ? 29.473  36.631  -68.281 1.00 33.54  ? 113 PRO L N   1 
ATOM   2550 C CA  . PRO B 2 119 ? 30.486  36.170  -67.330 1.00 32.59  ? 113 PRO L CA  1 
ATOM   2551 C C   . PRO B 2 119 ? 31.839  36.825  -67.551 1.00 39.89  ? 113 PRO L C   1 
ATOM   2552 O O   . PRO B 2 119 ? 32.223  37.169  -68.672 1.00 29.34  ? 113 PRO L O   1 
ATOM   2553 C CB  . PRO B 2 119 ? 30.563  34.664  -67.606 1.00 42.31  ? 113 PRO L CB  1 
ATOM   2554 C CG  . PRO B 2 119 ? 30.196  34.541  -69.042 1.00 29.03  ? 113 PRO L CG  1 
ATOM   2555 C CD  . PRO B 2 119 ? 29.157  35.605  -69.291 1.00 29.04  ? 113 PRO L CD  1 
ATOM   2556 N N   . SER B 2 120 ? 32.565  36.990  -66.449 1.00 39.75  ? 114 SER L N   1 
ATOM   2557 C CA  . SER B 2 120 ? 33.972  37.362  -66.493 1.00 32.93  ? 114 SER L CA  1 
ATOM   2558 C C   . SER B 2 120 ? 34.795  36.081  -66.524 1.00 40.30  ? 114 SER L C   1 
ATOM   2559 O O   . SER B 2 120 ? 34.691  35.251  -65.615 1.00 48.55  ? 114 SER L O   1 
ATOM   2560 C CB  . SER B 2 120 ? 34.347  38.225  -65.289 1.00 32.83  ? 114 SER L CB  1 
ATOM   2561 O OG  . SER B 2 120 ? 33.564  39.405  -65.240 1.00 42.92  ? 114 SER L OG  1 
ATOM   2562 N N   . VAL B 2 121 ? 35.602  35.915  -67.569 1.00 34.31  ? 115 VAL L N   1 
ATOM   2563 C CA  . VAL B 2 121 ? 36.320  34.670  -67.824 1.00 35.70  ? 115 VAL L CA  1 
ATOM   2564 C C   . VAL B 2 121 ? 37.790  34.868  -67.487 1.00 35.07  ? 115 VAL L C   1 
ATOM   2565 O O   . VAL B 2 121 ? 38.437  35.783  -68.009 1.00 43.82  ? 115 VAL L O   1 
ATOM   2566 C CB  . VAL B 2 121 ? 36.148  34.208  -69.279 1.00 38.80  ? 115 VAL L CB  1 
ATOM   2567 C CG1 . VAL B 2 121 ? 36.873  32.890  -69.502 1.00 35.23  ? 115 VAL L CG1 1 
ATOM   2568 C CG2 . VAL B 2 121 ? 34.673  34.075  -69.622 1.00 42.26  ? 115 VAL L CG2 1 
ATOM   2569 N N   . PHE B 2 122 ? 38.311  34.008  -66.615 1.00 31.00  ? 116 PHE L N   1 
ATOM   2570 C CA  . PHE B 2 122 ? 39.718  34.001  -66.252 1.00 36.41  ? 116 PHE L CA  1 
ATOM   2571 C C   . PHE B 2 122 ? 40.237  32.572  -66.316 1.00 42.92  ? 116 PHE L C   1 
ATOM   2572 O O   . PHE B 2 122 ? 39.504  31.618  -66.039 1.00 45.95  ? 116 PHE L O   1 
ATOM   2573 C CB  . PHE B 2 122 ? 39.946  34.573  -64.846 1.00 47.47  ? 116 PHE L CB  1 
ATOM   2574 C CG  . PHE B 2 122 ? 39.154  35.816  -64.559 1.00 42.90  ? 116 PHE L CG  1 
ATOM   2575 C CD1 . PHE B 2 122 ? 39.428  36.998  -65.226 1.00 49.95  ? 116 PHE L CD1 1 
ATOM   2576 C CD2 . PHE B 2 122 ? 38.140  35.805  -63.615 1.00 41.13  ? 116 PHE L CD2 1 
ATOM   2577 C CE1 . PHE B 2 122 ? 38.703  38.144  -64.962 1.00 47.22  ? 116 PHE L CE1 1 
ATOM   2578 C CE2 . PHE B 2 122 ? 37.411  36.949  -63.346 1.00 47.54  ? 116 PHE L CE2 1 
ATOM   2579 C CZ  . PHE B 2 122 ? 37.694  38.120  -64.021 1.00 48.55  ? 116 PHE L CZ  1 
ATOM   2580 N N   . ILE B 2 123 ? 41.508  32.428  -66.685 1.00 41.92  ? 117 ILE L N   1 
ATOM   2581 C CA  . ILE B 2 123 ? 42.145  31.121  -66.759 1.00 38.38  ? 117 ILE L CA  1 
ATOM   2582 C C   . ILE B 2 123 ? 43.413  31.150  -65.918 1.00 39.46  ? 117 ILE L C   1 
ATOM   2583 O O   . ILE B 2 123 ? 44.060  32.192  -65.766 1.00 49.75  ? 117 ILE L O   1 
ATOM   2584 C CB  . ILE B 2 123 ? 42.449  30.703  -68.218 1.00 36.69  ? 117 ILE L CB  1 
ATOM   2585 C CG1 . ILE B 2 123 ? 42.745  29.203  -68.294 1.00 37.63  ? 117 ILE L CG1 1 
ATOM   2586 C CG2 . ILE B 2 123 ? 43.601  31.517  -68.790 1.00 38.51  ? 117 ILE L CG2 1 
ATOM   2587 C CD1 . ILE B 2 123 ? 42.810  28.658  -69.702 1.00 45.77  ? 117 ILE L CD1 1 
ATOM   2588 N N   . PHE B 2 124 ? 43.754  29.999  -65.352 1.00 46.08  ? 118 PHE L N   1 
ATOM   2589 C CA  . PHE B 2 124 ? 44.899  29.874  -64.452 1.00 37.50  ? 118 PHE L CA  1 
ATOM   2590 C C   . PHE B 2 124 ? 45.777  28.714  -64.899 1.00 39.04  ? 118 PHE L C   1 
ATOM   2591 O O   . PHE B 2 124 ? 45.324  27.551  -64.861 1.00 44.74  ? 118 PHE L O   1 
ATOM   2592 C CB  . PHE B 2 124 ? 44.438  29.672  -63.011 1.00 35.20  ? 118 PHE L CB  1 
ATOM   2593 C CG  . PHE B 2 124 ? 43.656  30.828  -62.457 1.00 33.90  ? 118 PHE L CG  1 
ATOM   2594 C CD1 . PHE B 2 124 ? 42.290  30.925  -62.670 1.00 35.33  ? 118 PHE L CD1 1 
ATOM   2595 C CD2 . PHE B 2 124 ? 44.285  31.815  -61.718 1.00 36.85  ? 118 PHE L CD2 1 
ATOM   2596 C CE1 . PHE B 2 124 ? 41.569  31.988  -62.161 1.00 39.58  ? 118 PHE L CE1 1 
ATOM   2597 C CE2 . PHE B 2 124 ? 43.568  32.879  -61.205 1.00 47.34  ? 118 PHE L CE2 1 
ATOM   2598 C CZ  . PHE B 2 124 ? 42.209  32.965  -61.427 1.00 44.45  ? 118 PHE L CZ  1 
ATOM   2599 N N   . PRO B 2 125 ? 47.011  28.971  -65.338 1.00 49.03  ? 119 PRO L N   1 
ATOM   2600 C CA  . PRO B 2 125 ? 47.933  27.868  -65.591 1.00 41.01  ? 119 PRO L CA  1 
ATOM   2601 C C   . PRO B 2 125 ? 48.303  27.177  -64.296 1.00 45.92  ? 119 PRO L C   1 
ATOM   2602 O O   . PRO B 2 125 ? 48.291  27.798  -63.216 1.00 44.01  ? 119 PRO L O   1 
ATOM   2603 C CB  . PRO B 2 125 ? 49.149  28.564  -66.230 1.00 43.72  ? 119 PRO L CB  1 
ATOM   2604 C CG  . PRO B 2 125 ? 49.073  29.971  -65.745 1.00 51.86  ? 119 PRO L CG  1 
ATOM   2605 C CD  . PRO B 2 125 ? 47.610  30.283  -65.637 1.00 48.15  ? 119 PRO L CD  1 
ATOM   2606 N N   . PRO B 2 126 ? 48.629  25.885  -64.340 1.00 45.55  ? 120 PRO L N   1 
ATOM   2607 C CA  . PRO B 2 126 ? 48.968  25.169  -63.106 1.00 45.08  ? 120 PRO L CA  1 
ATOM   2608 C C   . PRO B 2 126 ? 50.217  25.740  -62.451 1.00 43.66  ? 120 PRO L C   1 
ATOM   2609 O O   . PRO B 2 126 ? 51.146  26.199  -63.120 1.00 42.90  ? 120 PRO L O   1 
ATOM   2610 C CB  . PRO B 2 126 ? 49.191  23.729  -63.581 1.00 34.47  ? 120 PRO L CB  1 
ATOM   2611 C CG  . PRO B 2 126 ? 49.564  23.865  -65.021 1.00 30.54  ? 120 PRO L CG  1 
ATOM   2612 C CD  . PRO B 2 126 ? 48.770  25.032  -65.533 1.00 37.71  ? 120 PRO L CD  1 
ATOM   2613 N N   . SER B 2 127 ? 50.225  25.713  -61.121 1.00 43.00  ? 121 SER L N   1 
ATOM   2614 C CA  . SER B 2 127 ? 51.351  26.225  -60.356 1.00 48.50  ? 121 SER L CA  1 
ATOM   2615 C C   . SER B 2 127 ? 52.510  25.237  -60.380 1.00 56.30  ? 121 SER L C   1 
ATOM   2616 O O   . SER B 2 127 ? 52.316  24.018  -60.418 1.00 45.25  ? 121 SER L O   1 
ATOM   2617 C CB  . SER B 2 127 ? 50.936  26.507  -58.910 1.00 51.61  ? 121 SER L CB  1 
ATOM   2618 O OG  . SER B 2 127 ? 50.517  25.320  -58.257 1.00 53.66  ? 121 SER L OG  1 
ATOM   2619 N N   . ASP B 2 128 ? 53.731  25.783  -60.346 1.00 56.15  ? 122 ASP L N   1 
ATOM   2620 C CA  . ASP B 2 128 ? 54.928  24.948  -60.393 1.00 54.66  ? 122 ASP L CA  1 
ATOM   2621 C C   . ASP B 2 128 ? 54.973  23.952  -59.242 1.00 50.90  ? 122 ASP L C   1 
ATOM   2622 O O   . ASP B 2 128 ? 55.588  22.887  -59.369 1.00 42.96  ? 122 ASP L O   1 
ATOM   2623 C CB  . ASP B 2 128 ? 56.181  25.825  -60.382 1.00 49.47  ? 122 ASP L CB  1 
ATOM   2624 C CG  . ASP B 2 128 ? 56.416  26.524  -61.707 1.00 78.58  ? 122 ASP L CG  1 
ATOM   2625 O OD1 . ASP B 2 128 ? 56.438  25.834  -62.748 1.00 78.01  ? 122 ASP L OD1 1 
ATOM   2626 O OD2 . ASP B 2 128 ? 56.573  27.764  -61.707 1.00 81.93  ? 122 ASP L OD2 1 
ATOM   2627 N N   . GLU B 2 129 ? 54.337  24.278  -58.113 1.00 54.44  ? 123 GLU L N   1 
ATOM   2628 C CA  . GLU B 2 129 ? 54.258  23.322  -57.013 1.00 59.29  ? 123 GLU L CA  1 
ATOM   2629 C C   . GLU B 2 129 ? 53.498  22.068  -57.425 1.00 60.52  ? 123 GLU L C   1 
ATOM   2630 O O   . GLU B 2 129 ? 53.928  20.947  -57.129 1.00 50.23  ? 123 GLU L O   1 
ATOM   2631 C CB  . GLU B 2 129 ? 53.598  23.967  -55.795 1.00 60.49  ? 123 GLU L CB  1 
ATOM   2632 C CG  . GLU B 2 129 ? 53.109  22.950  -54.775 1.00 69.87  ? 123 GLU L CG  1 
ATOM   2633 C CD  . GLU B 2 129 ? 52.780  23.564  -53.430 1.00 74.76  ? 123 GLU L CD  1 
ATOM   2634 O OE1 . GLU B 2 129 ? 52.361  24.740  -53.392 1.00 68.82  ? 123 GLU L OE1 1 
ATOM   2635 O OE2 . GLU B 2 129 ? 52.950  22.866  -52.408 1.00 79.31  ? 123 GLU L OE2 1 
ATOM   2636 N N   . GLN B 2 130 ? 52.366  22.237  -58.113 1.00 61.30  ? 124 GLN L N   1 
ATOM   2637 C CA  . GLN B 2 130 ? 51.594  21.079  -58.548 1.00 57.84  ? 124 GLN L CA  1 
ATOM   2638 C C   . GLN B 2 130 ? 52.301  20.317  -59.661 1.00 61.55  ? 124 GLN L C   1 
ATOM   2639 O O   . GLN B 2 130 ? 52.174  19.089  -59.745 1.00 58.62  ? 124 GLN L O   1 
ATOM   2640 C CB  . GLN B 2 130 ? 50.202  21.509  -59.005 1.00 52.37  ? 124 GLN L CB  1 
ATOM   2641 C CG  . GLN B 2 130 ? 49.228  20.351  -59.138 1.00 51.88  ? 124 GLN L CG  1 
ATOM   2642 C CD  . GLN B 2 130 ? 48.028  20.688  -60.000 1.00 56.77  ? 124 GLN L CD  1 
ATOM   2643 O OE1 . GLN B 2 130 ? 47.088  19.900  -60.109 1.00 49.00  ? 124 GLN L OE1 1 
ATOM   2644 N NE2 . GLN B 2 130 ? 48.055  21.862  -60.620 1.00 48.06  ? 124 GLN L NE2 1 
ATOM   2645 N N   . LEU B 2 131 ? 53.042  21.020  -60.523 1.00 58.02  ? 125 LEU L N   1 
ATOM   2646 C CA  . LEU B 2 131 ? 53.791  20.341  -61.575 1.00 46.10  ? 125 LEU L CA  1 
ATOM   2647 C C   . LEU B 2 131 ? 54.819  19.386  -60.987 1.00 55.17  ? 125 LEU L C   1 
ATOM   2648 O O   . LEU B 2 131 ? 55.016  18.279  -61.501 1.00 61.83  ? 125 LEU L O   1 
ATOM   2649 C CB  . LEU B 2 131 ? 54.477  21.360  -62.486 1.00 41.77  ? 125 LEU L CB  1 
ATOM   2650 C CG  . LEU B 2 131 ? 53.701  21.863  -63.704 1.00 39.95  ? 125 LEU L CG  1 
ATOM   2651 C CD1 . LEU B 2 131 ? 53.126  20.701  -64.499 1.00 46.01  ? 125 LEU L CD1 1 
ATOM   2652 C CD2 . LEU B 2 131 ? 52.609  22.825  -63.294 1.00 50.25  ? 125 LEU L CD2 1 
ATOM   2653 N N   . LYS B 2 132 ? 55.480  19.793  -59.901 1.00 59.67  ? 126 LYS L N   1 
ATOM   2654 C CA  . LYS B 2 132 ? 56.502  18.950  -59.296 1.00 58.97  ? 126 LYS L CA  1 
ATOM   2655 C C   . LYS B 2 132 ? 55.931  17.643  -58.757 1.00 60.55  ? 126 LYS L C   1 
ATOM   2656 O O   . LYS B 2 132 ? 56.686  16.682  -58.571 1.00 67.33  ? 126 LYS L O   1 
ATOM   2657 C CB  . LYS B 2 132 ? 57.219  19.712  -58.181 1.00 53.60  ? 126 LYS L CB  1 
ATOM   2658 C CG  . LYS B 2 132 ? 58.720  19.500  -58.190 1.00 70.82  ? 126 LYS L CG  1 
ATOM   2659 C CD  . LYS B 2 132 ? 59.366  19.931  -56.889 1.00 79.28  ? 126 LYS L CD  1 
ATOM   2660 C CE  . LYS B 2 132 ? 60.727  19.269  -56.735 1.00 77.10  ? 126 LYS L CE  1 
ATOM   2661 N NZ  . LYS B 2 132 ? 61.428  19.687  -55.491 1.00 70.95  ? 126 LYS L NZ  1 
ATOM   2662 N N   . SER B 2 133 ? 54.625  17.581  -58.505 1.00 55.79  ? 127 SER L N   1 
ATOM   2663 C CA  . SER B 2 133 ? 53.979  16.355  -58.058 1.00 57.05  ? 127 SER L CA  1 
ATOM   2664 C C   . SER B 2 133 ? 53.544  15.458  -59.211 1.00 54.76  ? 127 SER L C   1 
ATOM   2665 O O   . SER B 2 133 ? 53.035  14.360  -58.963 1.00 53.04  ? 127 SER L O   1 
ATOM   2666 C CB  . SER B 2 133 ? 52.771  16.685  -57.173 1.00 56.69  ? 127 SER L CB  1 
ATOM   2667 O OG  . SER B 2 133 ? 51.822  17.472  -57.870 1.00 57.79  ? 127 SER L OG  1 
ATOM   2668 N N   . GLY B 2 134 ? 53.726  15.895  -60.457 1.00 49.95  ? 128 GLY L N   1 
ATOM   2669 C CA  . GLY B 2 134 ? 53.439  15.071  -61.613 1.00 57.81  ? 128 GLY L CA  1 
ATOM   2670 C C   . GLY B 2 134 ? 52.059  15.231  -62.216 1.00 60.62  ? 128 GLY L C   1 
ATOM   2671 O O   . GLY B 2 134 ? 51.726  14.494  -63.153 1.00 58.61  ? 128 GLY L O   1 
ATOM   2672 N N   . THR B 2 135 ? 51.249  16.164  -61.720 1.00 50.92  ? 129 THR L N   1 
ATOM   2673 C CA  . THR B 2 135 ? 49.909  16.399  -62.242 1.00 47.00  ? 129 THR L CA  1 
ATOM   2674 C C   . THR B 2 135 ? 49.719  17.887  -62.496 1.00 49.32  ? 129 THR L C   1 
ATOM   2675 O O   . THR B 2 135 ? 50.135  18.721  -61.687 1.00 53.70  ? 129 THR L O   1 
ATOM   2676 C CB  . THR B 2 135 ? 48.835  15.878  -61.271 1.00 43.42  ? 129 THR L CB  1 
ATOM   2677 O OG1 . THR B 2 135 ? 48.886  14.447  -61.224 1.00 51.44  ? 129 THR L OG1 1 
ATOM   2678 C CG2 . THR B 2 135 ? 47.443  16.315  -61.706 1.00 43.43  ? 129 THR L CG2 1 
ATOM   2679 N N   . ALA B 2 136 ? 49.100  18.215  -63.629 1.00 49.95  ? 130 ALA L N   1 
ATOM   2680 C CA  . ALA B 2 136 ? 48.808  19.592  -64.003 1.00 52.68  ? 130 ALA L CA  1 
ATOM   2681 C C   . ALA B 2 136 ? 47.302  19.807  -64.054 1.00 45.27  ? 130 ALA L C   1 
ATOM   2682 O O   . ALA B 2 136 ? 46.563  18.979  -64.597 1.00 45.69  ? 130 ALA L O   1 
ATOM   2683 C CB  . ALA B 2 136 ? 49.428  19.944  -65.358 1.00 39.61  ? 130 ALA L CB  1 
ATOM   2684 N N   . SER B 2 137 ? 46.852  20.922  -63.483 1.00 37.79  ? 131 SER L N   1 
ATOM   2685 C CA  . SER B 2 137 ? 45.444  21.291  -63.476 1.00 39.38  ? 131 SER L CA  1 
ATOM   2686 C C   . SER B 2 137 ? 45.292  22.706  -64.013 1.00 38.42  ? 131 SER L C   1 
ATOM   2687 O O   . SER B 2 137 ? 45.940  23.634  -63.519 1.00 38.31  ? 131 SER L O   1 
ATOM   2688 C CB  . SER B 2 137 ? 44.850  21.190  -62.068 1.00 38.99  ? 131 SER L CB  1 
ATOM   2689 O OG  . SER B 2 137 ? 44.888  19.855  -61.594 1.00 52.12  ? 131 SER L OG  1 
ATOM   2690 N N   . VAL B 2 138 ? 44.432  22.868  -65.015 1.00 34.69  ? 132 VAL L N   1 
ATOM   2691 C CA  . VAL B 2 138 ? 44.145  24.164  -65.618 1.00 36.34  ? 132 VAL L CA  1 
ATOM   2692 C C   . VAL B 2 138 ? 42.719  24.542  -65.243 1.00 31.96  ? 132 VAL L C   1 
ATOM   2693 O O   . VAL B 2 138 ? 41.773  23.804  -65.544 1.00 41.60  ? 132 VAL L O   1 
ATOM   2694 C CB  . VAL B 2 138 ? 44.327  24.135  -67.143 1.00 31.04  ? 132 VAL L CB  1 
ATOM   2695 C CG1 . VAL B 2 138 ? 44.190  25.535  -67.718 1.00 34.35  ? 132 VAL L CG1 1 
ATOM   2696 C CG2 . VAL B 2 138 ? 45.676  23.530  -67.503 1.00 25.37  ? 132 VAL L CG2 1 
ATOM   2697 N N   . VAL B 2 139 ? 42.563  25.695  -64.596 1.00 33.13  ? 133 VAL L N   1 
ATOM   2698 C CA  . VAL B 2 139 ? 41.288  26.129  -64.035 1.00 33.44  ? 133 VAL L CA  1 
ATOM   2699 C C   . VAL B 2 139 ? 40.772  27.308  -64.847 1.00 30.33  ? 133 VAL L C   1 
ATOM   2700 O O   . VAL B 2 139 ? 41.517  28.258  -65.118 1.00 41.04  ? 133 VAL L O   1 
ATOM   2701 C CB  . VAL B 2 139 ? 41.429  26.506  -62.549 1.00 31.88  ? 133 VAL L CB  1 
ATOM   2702 C CG1 . VAL B 2 139 ? 40.095  26.972  -61.987 1.00 28.05  ? 133 VAL L CG1 1 
ATOM   2703 C CG2 . VAL B 2 139 ? 41.967  25.328  -61.752 1.00 35.38  ? 133 VAL L CG2 1 
ATOM   2704 N N   . CYS B 2 140 ? 39.502  27.242  -65.240 1.00 35.71  ? 134 CYS L N   1 
ATOM   2705 C CA  . CYS B 2 140 ? 38.830  28.324  -65.947 1.00 40.18  ? 134 CYS L CA  1 
ATOM   2706 C C   . CYS B 2 140 ? 37.654  28.800  -65.107 1.00 37.51  ? 134 CYS L C   1 
ATOM   2707 O O   . CYS B 2 140 ? 36.835  27.988  -64.664 1.00 44.30  ? 134 CYS L O   1 
ATOM   2708 C CB  . CYS B 2 140 ? 38.355  27.868  -67.328 1.00 33.56  ? 134 CYS L CB  1 
ATOM   2709 S SG  . CYS B 2 140 ? 37.930  29.206  -68.462 1.00 54.58  ? 134 CYS L SG  1 
ATOM   2710 N N   . LEU B 2 141 ? 37.573  30.110  -64.892 1.00 32.30  ? 135 LEU L N   1 
ATOM   2711 C CA  . LEU B 2 141 ? 36.588  30.706  -63.998 1.00 35.49  ? 135 LEU L CA  1 
ATOM   2712 C C   . LEU B 2 141 ? 35.599  31.544  -64.798 1.00 35.87  ? 135 LEU L C   1 
ATOM   2713 O O   . LEU B 2 141 ? 36.000  32.451  -65.535 1.00 36.11  ? 135 LEU L O   1 
ATOM   2714 C CB  . LEU B 2 141 ? 37.273  31.565  -62.935 1.00 44.74  ? 135 LEU L CB  1 
ATOM   2715 C CG  . LEU B 2 141 ? 36.353  32.393  -62.035 1.00 40.64  ? 135 LEU L CG  1 
ATOM   2716 C CD1 . LEU B 2 141 ? 35.444  31.489  -61.223 1.00 31.86  ? 135 LEU L CD1 1 
ATOM   2717 C CD2 . LEU B 2 141 ? 37.165  33.299  -61.125 1.00 31.94  ? 135 LEU L CD2 1 
ATOM   2718 N N   . LEU B 2 142 ? 34.313  31.237  -64.646 1.00 35.51  ? 136 LEU L N   1 
ATOM   2719 C CA  . LEU B 2 142 ? 33.217  32.063  -65.146 1.00 31.42  ? 136 LEU L CA  1 
ATOM   2720 C C   . LEU B 2 142 ? 32.605  32.754  -63.935 1.00 39.34  ? 136 LEU L C   1 
ATOM   2721 O O   . LEU B 2 142 ? 31.982  32.098  -63.093 1.00 32.33  ? 136 LEU L O   1 
ATOM   2722 C CB  . LEU B 2 142 ? 32.178  31.221  -65.884 1.00 33.92  ? 136 LEU L CB  1 
ATOM   2723 C CG  . LEU B 2 142 ? 32.400  30.819  -67.344 1.00 29.62  ? 136 LEU L CG  1 
ATOM   2724 C CD1 . LEU B 2 142 ? 33.703  30.060  -67.545 1.00 30.56  ? 136 LEU L CD1 1 
ATOM   2725 C CD2 . LEU B 2 142 ? 31.221  29.985  -67.820 1.00 30.87  ? 136 LEU L CD2 1 
ATOM   2726 N N   . ASN B 2 143 ? 32.780  34.068  -63.842 1.00 40.11  ? 137 ASN L N   1 
ATOM   2727 C CA  . ASN B 2 143 ? 32.495  34.804  -62.617 1.00 35.96  ? 137 ASN L CA  1 
ATOM   2728 C C   . ASN B 2 143 ? 31.338  35.773  -62.821 1.00 39.86  ? 137 ASN L C   1 
ATOM   2729 O O   . ASN B 2 143 ? 31.352  36.576  -63.760 1.00 32.76  ? 137 ASN L O   1 
ATOM   2730 C CB  . ASN B 2 143 ? 33.740  35.561  -62.145 1.00 25.70  ? 137 ASN L CB  1 
ATOM   2731 C CG  . ASN B 2 143 ? 33.597  36.095  -60.734 1.00 39.94  ? 137 ASN L CG  1 
ATOM   2732 O OD1 . ASN B 2 143 ? 33.273  37.265  -60.529 1.00 55.36  ? 137 ASN L OD1 1 
ATOM   2733 N ND2 . ASN B 2 143 ? 33.839  35.238  -59.750 1.00 39.94  ? 137 ASN L ND2 1 
ATOM   2734 N N   . ASN B 2 144 ? 30.343  35.688  -61.935 1.00 41.02  ? 138 ASN L N   1 
ATOM   2735 C CA  . ASN B 2 144 ? 29.267  36.674  -61.808 1.00 40.07  ? 138 ASN L CA  1 
ATOM   2736 C C   . ASN B 2 144 ? 28.498  36.842  -63.122 1.00 38.22  ? 138 ASN L C   1 
ATOM   2737 O O   . ASN B 2 144 ? 28.505  37.898  -63.758 1.00 51.82  ? 138 ASN L O   1 
ATOM   2738 C CB  . ASN B 2 144 ? 29.821  38.017  -61.315 1.00 37.66  ? 138 ASN L CB  1 
ATOM   2739 C CG  . ASN B 2 144 ? 30.232  37.976  -59.857 1.00 36.74  ? 138 ASN L CG  1 
ATOM   2740 O OD1 . ASN B 2 144 ? 29.659  37.233  -59.060 1.00 49.59  ? 138 ASN L OD1 1 
ATOM   2741 N ND2 . ASN B 2 144 ? 31.227  38.777  -59.499 1.00 57.15  ? 138 ASN L ND2 1 
ATOM   2742 N N   . PHE B 2 145 ? 27.822  35.763  -63.511 1.00 35.62  ? 139 PHE L N   1 
ATOM   2743 C CA  . PHE B 2 145 ? 26.974  35.773  -64.692 1.00 34.22  ? 139 PHE L CA  1 
ATOM   2744 C C   . PHE B 2 145 ? 25.559  35.332  -64.342 1.00 43.31  ? 139 PHE L C   1 
ATOM   2745 O O   . PHE B 2 145 ? 25.303  34.741  -63.289 1.00 32.25  ? 139 PHE L O   1 
ATOM   2746 C CB  . PHE B 2 145 ? 27.534  34.874  -65.804 1.00 33.62  ? 139 PHE L CB  1 
ATOM   2747 C CG  . PHE B 2 145 ? 27.660  33.426  -65.421 1.00 31.83  ? 139 PHE L CG  1 
ATOM   2748 C CD1 . PHE B 2 145 ? 28.807  32.957  -64.802 1.00 32.45  ? 139 PHE L CD1 1 
ATOM   2749 C CD2 . PHE B 2 145 ? 26.642  32.529  -65.702 1.00 32.25  ? 139 PHE L CD2 1 
ATOM   2750 C CE1 . PHE B 2 145 ? 28.929  31.623  -64.454 1.00 43.31  ? 139 PHE L CE1 1 
ATOM   2751 C CE2 . PHE B 2 145 ? 26.758  31.196  -65.358 1.00 33.77  ? 139 PHE L CE2 1 
ATOM   2752 C CZ  . PHE B 2 145 ? 27.903  30.742  -64.734 1.00 38.48  ? 139 PHE L CZ  1 
ATOM   2753 N N   . TYR B 2 146 ? 24.635  35.647  -65.255 1.00 43.37  ? 140 TYR L N   1 
ATOM   2754 C CA  . TYR B 2 146 ? 23.243  35.232  -65.171 1.00 36.26  ? 140 TYR L CA  1 
ATOM   2755 C C   . TYR B 2 146 ? 22.685  35.231  -66.582 1.00 35.20  ? 140 TYR L C   1 
ATOM   2756 O O   . TYR B 2 146 ? 22.985  36.159  -67.346 1.00 33.57  ? 140 TYR L O   1 
ATOM   2757 C CB  . TYR B 2 146 ? 22.425  36.168  -64.274 1.00 35.64  ? 140 TYR L CB  1 
ATOM   2758 C CG  . TYR B 2 146 ? 20.984  35.745  -64.115 1.00 32.18  ? 140 TYR L CG  1 
ATOM   2759 C CD1 . TYR B 2 146 ? 20.599  34.896  -63.086 1.00 42.11  ? 140 TYR L CD1 1 
ATOM   2760 C CD2 . TYR B 2 146 ? 20.008  36.187  -65.000 1.00 32.98  ? 140 TYR L CD2 1 
ATOM   2761 C CE1 . TYR B 2 146 ? 19.285  34.503  -62.940 1.00 50.34  ? 140 TYR L CE1 1 
ATOM   2762 C CE2 . TYR B 2 146 ? 18.692  35.798  -64.862 1.00 41.13  ? 140 TYR L CE2 1 
ATOM   2763 C CZ  . TYR B 2 146 ? 18.336  34.957  -63.831 1.00 47.49  ? 140 TYR L CZ  1 
ATOM   2764 O OH  . TYR B 2 146 ? 17.024  34.568  -63.689 1.00 56.31  ? 140 TYR L OH  1 
ATOM   2765 N N   . PRO B 2 147 ? 21.874  34.235  -66.967 1.00 39.15  ? 141 PRO L N   1 
ATOM   2766 C CA  . PRO B 2 147 ? 21.375  33.100  -66.174 1.00 39.64  ? 141 PRO L CA  1 
ATOM   2767 C C   . PRO B 2 147 ? 22.415  32.001  -65.953 1.00 38.37  ? 141 PRO L C   1 
ATOM   2768 O O   . PRO B 2 147 ? 23.523  32.062  -66.477 1.00 37.17  ? 141 PRO L O   1 
ATOM   2769 C CB  . PRO B 2 147 ? 20.192  32.601  -67.013 1.00 48.71  ? 141 PRO L CB  1 
ATOM   2770 C CG  . PRO B 2 147 ? 20.598  32.903  -68.423 1.00 38.28  ? 141 PRO L CG  1 
ATOM   2771 C CD  . PRO B 2 147 ? 21.347  34.211  -68.344 1.00 35.64  ? 141 PRO L CD  1 
ATOM   2772 N N   . ARG B 2 148 ? 22.043  30.981  -65.174 1.00 36.61  ? 142 ARG L N   1 
ATOM   2773 C CA  . ARG B 2 148 ? 22.956  29.903  -64.805 1.00 33.48  ? 142 ARG L CA  1 
ATOM   2774 C C   . ARG B 2 148 ? 23.468  29.116  -66.006 1.00 38.62  ? 142 ARG L C   1 
ATOM   2775 O O   . ARG B 2 148 ? 24.555  28.532  -65.932 1.00 42.05  ? 142 ARG L O   1 
ATOM   2776 C CB  . ARG B 2 148 ? 22.247  28.961  -63.825 1.00 29.87  ? 142 ARG L CB  1 
ATOM   2777 C CG  . ARG B 2 148 ? 23.098  27.836  -63.265 1.00 30.34  ? 142 ARG L CG  1 
ATOM   2778 C CD  . ARG B 2 148 ? 22.240  26.835  -62.515 1.00 30.97  ? 142 ARG L CD  1 
ATOM   2779 N NE  . ARG B 2 148 ? 23.000  25.666  -62.092 1.00 35.49  ? 142 ARG L NE  1 
ATOM   2780 C CZ  . ARG B 2 148 ? 23.558  25.529  -60.897 1.00 56.60  ? 142 ARG L CZ  1 
ATOM   2781 N NH1 . ARG B 2 148 ? 23.462  26.475  -59.977 1.00 52.90  ? 142 ARG L NH1 1 
ATOM   2782 N NH2 . ARG B 2 148 ? 24.227  24.414  -60.617 1.00 57.51  ? 142 ARG L NH2 1 
ATOM   2783 N N   . GLU B 2 149 ? 22.726  29.093  -67.111 1.00 33.09  ? 143 GLU L N   1 
ATOM   2784 C CA  . GLU B 2 149 ? 23.070  28.231  -68.236 1.00 30.90  ? 143 GLU L CA  1 
ATOM   2785 C C   . GLU B 2 149 ? 24.280  28.781  -68.984 1.00 27.40  ? 143 GLU L C   1 
ATOM   2786 O O   . GLU B 2 149 ? 24.258  29.916  -69.472 1.00 30.72  ? 143 GLU L O   1 
ATOM   2787 C CB  . GLU B 2 149 ? 21.873  28.093  -69.175 1.00 27.99  ? 143 GLU L CB  1 
ATOM   2788 C CG  . GLU B 2 149 ? 20.599  27.591  -68.504 1.00 53.41  ? 143 GLU L CG  1 
ATOM   2789 C CD  . GLU B 2 149 ? 19.828  28.696  -67.803 1.00 58.74  ? 143 GLU L CD  1 
ATOM   2790 O OE1 . GLU B 2 149 ? 19.295  29.585  -68.500 1.00 68.86  ? 143 GLU L OE1 1 
ATOM   2791 O OE2 . GLU B 2 149 ? 19.764  28.680  -66.555 1.00 58.78  ? 143 GLU L OE2 1 
ATOM   2792 N N   . ALA B 2 150 ? 25.331  27.968  -69.085 1.00 37.72  ? 144 ALA L N   1 
ATOM   2793 C CA  . ALA B 2 150 ? 26.536  28.334  -69.817 1.00 25.43  ? 144 ALA L CA  1 
ATOM   2794 C C   . ALA B 2 150 ? 27.236  27.066  -70.282 1.00 26.30  ? 144 ALA L C   1 
ATOM   2795 O O   . ALA B 2 150 ? 27.026  25.982  -69.733 1.00 38.46  ? 144 ALA L O   1 
ATOM   2796 C CB  . ALA B 2 150 ? 27.485  29.186  -68.963 1.00 29.65  ? 144 ALA L CB  1 
ATOM   2797 N N   . LYS B 2 151 ? 28.076  27.213  -71.304 1.00 28.84  ? 145 LYS L N   1 
ATOM   2798 C CA  . LYS B 2 151 ? 28.829  26.103  -71.873 1.00 35.13  ? 145 LYS L CA  1 
ATOM   2799 C C   . LYS B 2 151 ? 30.321  26.394  -71.799 1.00 31.12  ? 145 LYS L C   1 
ATOM   2800 O O   . LYS B 2 151 ? 30.763  27.504  -72.114 1.00 36.40  ? 145 LYS L O   1 
ATOM   2801 C CB  . LYS B 2 151 ? 28.427  25.842  -73.329 1.00 34.09  ? 145 LYS L CB  1 
ATOM   2802 C CG  . LYS B 2 151 ? 29.121  24.640  -73.951 1.00 33.35  ? 145 LYS L CG  1 
ATOM   2803 C CD  . LYS B 2 151 ? 29.117  24.715  -75.468 1.00 36.33  ? 145 LYS L CD  1 
ATOM   2804 C CE  . LYS B 2 151 ? 27.705  24.814  -76.017 1.00 50.10  ? 145 LYS L CE  1 
ATOM   2805 N NZ  . LYS B 2 151 ? 27.705  24.949  -77.499 1.00 58.58  ? 145 LYS L NZ  1 
ATOM   2806 N N   . VAL B 2 152 ? 31.093  25.394  -71.381 1.00 33.23  ? 146 VAL L N   1 
ATOM   2807 C CA  . VAL B 2 152 ? 32.545  25.493  -71.294 1.00 28.06  ? 146 VAL L CA  1 
ATOM   2808 C C   . VAL B 2 152 ? 33.155  24.326  -72.055 1.00 28.31  ? 146 VAL L C   1 
ATOM   2809 O O   . VAL B 2 152 ? 32.822  23.165  -71.792 1.00 47.73  ? 146 VAL L O   1 
ATOM   2810 C CB  . VAL B 2 152 ? 33.034  25.500  -69.834 1.00 32.90  ? 146 VAL L CB  1 
ATOM   2811 C CG1 . VAL B 2 152 ? 34.549  25.388  -69.783 1.00 39.83  ? 146 VAL L CG1 1 
ATOM   2812 C CG2 . VAL B 2 152 ? 32.567  26.761  -69.126 1.00 37.55  ? 146 VAL L CG2 1 
ATOM   2813 N N   . GLN B 2 153 ? 34.045  24.633  -72.996 1.00 27.14  ? 147 GLN L N   1 
ATOM   2814 C CA  . GLN B 2 153 ? 34.753  23.628  -73.774 1.00 30.39  ? 147 GLN L CA  1 
ATOM   2815 C C   . GLN B 2 153 ? 36.251  23.864  -73.656 1.00 40.76  ? 147 GLN L C   1 
ATOM   2816 O O   . GLN B 2 153 ? 36.714  25.007  -73.724 1.00 41.46  ? 147 GLN L O   1 
ATOM   2817 C CB  . GLN B 2 153 ? 34.341  23.664  -75.250 1.00 40.41  ? 147 GLN L CB  1 
ATOM   2818 C CG  . GLN B 2 153 ? 32.857  23.468  -75.493 1.00 38.12  ? 147 GLN L CG  1 
ATOM   2819 C CD  . GLN B 2 153 ? 32.472  23.726  -76.936 1.00 43.70  ? 147 GLN L CD  1 
ATOM   2820 O OE1 . GLN B 2 153 ? 32.130  24.848  -77.308 1.00 49.07  ? 147 GLN L OE1 1 
ATOM   2821 N NE2 . GLN B 2 153 ? 32.530  22.685  -77.758 1.00 41.32  ? 147 GLN L NE2 1 
ATOM   2822 N N   . TRP B 2 154 ? 37.003  22.781  -73.487 1.00 27.41  ? 148 TRP L N   1 
ATOM   2823 C CA  . TRP B 2 154 ? 38.454  22.843  -73.386 1.00 31.03  ? 148 TRP L CA  1 
ATOM   2824 C C   . TRP B 2 154 ? 39.078  22.415  -74.706 1.00 36.96  ? 148 TRP L C   1 
ATOM   2825 O O   . TRP B 2 154 ? 38.723  21.367  -75.256 1.00 41.32  ? 148 TRP L O   1 
ATOM   2826 C CB  . TRP B 2 154 ? 38.964  21.954  -72.251 1.00 32.38  ? 148 TRP L CB  1 
ATOM   2827 C CG  . TRP B 2 154 ? 38.752  22.536  -70.894 1.00 33.86  ? 148 TRP L CG  1 
ATOM   2828 C CD1 . TRP B 2 154 ? 37.746  22.241  -70.021 1.00 30.70  ? 148 TRP L CD1 1 
ATOM   2829 C CD2 . TRP B 2 154 ? 39.566  23.522  -70.251 1.00 36.53  ? 148 TRP L CD2 1 
ATOM   2830 N NE1 . TRP B 2 154 ? 37.885  22.981  -68.872 1.00 37.30  ? 148 TRP L NE1 1 
ATOM   2831 C CE2 . TRP B 2 154 ? 38.995  23.776  -68.989 1.00 40.06  ? 148 TRP L CE2 1 
ATOM   2832 C CE3 . TRP B 2 154 ? 40.722  24.216  -70.621 1.00 34.47  ? 148 TRP L CE3 1 
ATOM   2833 C CZ2 . TRP B 2 154 ? 39.542  24.692  -68.094 1.00 39.60  ? 148 TRP L CZ2 1 
ATOM   2834 C CZ3 . TRP B 2 154 ? 41.263  25.126  -69.732 1.00 37.17  ? 148 TRP L CZ3 1 
ATOM   2835 C CH2 . TRP B 2 154 ? 40.673  25.357  -68.483 1.00 41.64  ? 148 TRP L CH2 1 
ATOM   2836 N N   . LYS B 2 155 ? 40.004  23.227  -75.209 1.00 38.22  ? 149 LYS L N   1 
ATOM   2837 C CA  . LYS B 2 155 ? 40.736  22.924  -76.432 1.00 39.03  ? 149 LYS L CA  1 
ATOM   2838 C C   . LYS B 2 155 ? 42.224  23.053  -76.151 1.00 44.21  ? 149 LYS L C   1 
ATOM   2839 O O   . LYS B 2 155 ? 42.693  24.124  -75.751 1.00 49.76  ? 149 LYS L O   1 
ATOM   2840 C CB  . LYS B 2 155 ? 40.315  23.852  -77.577 1.00 43.04  ? 149 LYS L CB  1 
ATOM   2841 C CG  . LYS B 2 155 ? 38.914  23.580  -78.102 1.00 43.61  ? 149 LYS L CG  1 
ATOM   2842 C CD  . LYS B 2 155 ? 38.540  24.526  -79.232 1.00 45.43  ? 149 LYS L CD  1 
ATOM   2843 C CE  . LYS B 2 155 ? 37.189  24.161  -79.828 1.00 58.19  ? 149 LYS L CE  1 
ATOM   2844 N NZ  . LYS B 2 155 ? 36.738  25.159  -80.837 1.00 42.26  ? 149 LYS L NZ  1 
ATOM   2845 N N   . VAL B 2 156 ? 42.960  21.964  -76.357 1.00 41.63  ? 150 VAL L N   1 
ATOM   2846 C CA  . VAL B 2 156 ? 44.403  21.921  -76.151 1.00 44.34  ? 150 VAL L CA  1 
ATOM   2847 C C   . VAL B 2 156 ? 45.050  21.804  -77.523 1.00 41.67  ? 150 VAL L C   1 
ATOM   2848 O O   . VAL B 2 156 ? 44.956  20.756  -78.174 1.00 46.17  ? 150 VAL L O   1 
ATOM   2849 C CB  . VAL B 2 156 ? 44.813  20.757  -75.239 1.00 48.21  ? 150 VAL L CB  1 
ATOM   2850 C CG1 . VAL B 2 156 ? 46.322  20.634  -75.185 1.00 51.18  ? 150 VAL L CG1 1 
ATOM   2851 C CG2 . VAL B 2 156 ? 44.243  20.952  -73.843 1.00 46.24  ? 150 VAL L CG2 1 
ATOM   2852 N N   . ASP B 2 157 ? 45.716  22.875  -77.957 1.00 46.28  ? 151 ASP L N   1 
ATOM   2853 C CA  . ASP B 2 157 ? 46.254  22.974  -79.314 1.00 43.65  ? 151 ASP L CA  1 
ATOM   2854 C C   . ASP B 2 157 ? 45.169  22.676  -80.347 1.00 41.44  ? 151 ASP L C   1 
ATOM   2855 O O   . ASP B 2 157 ? 45.358  21.897  -81.284 1.00 32.58  ? 151 ASP L O   1 
ATOM   2856 C CB  . ASP B 2 157 ? 47.467  22.059  -79.499 1.00 46.83  ? 151 ASP L CB  1 
ATOM   2857 C CG  . ASP B 2 157 ? 48.745  22.669  -78.954 1.00 55.62  ? 151 ASP L CG  1 
ATOM   2858 O OD1 . ASP B 2 157 ? 48.857  23.913  -78.952 1.00 56.35  ? 151 ASP L OD1 1 
ATOM   2859 O OD2 . ASP B 2 157 ? 49.639  21.906  -78.532 1.00 48.98  ? 151 ASP L OD2 1 
ATOM   2860 N N   . ASN B 2 158 ? 44.008  23.302  -80.144 1.00 40.87  ? 152 ASN L N   1 
ATOM   2861 C CA  . ASN B 2 158 ? 42.833  23.169  -81.004 1.00 47.37  ? 152 ASN L CA  1 
ATOM   2862 C C   . ASN B 2 158 ? 42.300  21.739  -81.047 1.00 42.92  ? 152 ASN L C   1 
ATOM   2863 O O   . ASN B 2 158 ? 41.635  21.349  -82.012 1.00 44.13  ? 152 ASN L O   1 
ATOM   2864 C CB  . ASN B 2 158 ? 43.120  23.673  -82.424 1.00 53.26  ? 152 ASN L CB  1 
ATOM   2865 C CG  . ASN B 2 158 ? 41.910  24.322  -83.069 1.00 63.80  ? 152 ASN L CG  1 
ATOM   2866 O OD1 . ASN B 2 158 ? 40.784  23.841  -82.934 1.00 54.33  ? 152 ASN L OD1 1 
ATOM   2867 N ND2 . ASN B 2 158 ? 42.137  25.430  -83.767 1.00 64.88  ? 152 ASN L ND2 1 
ATOM   2868 N N   . ALA B 2 159 ? 42.577  20.946  -80.015 1.00 43.63  ? 153 ALA L N   1 
ATOM   2869 C CA  . ALA B 2 159 ? 42.049  19.594  -79.893 1.00 37.77  ? 153 ALA L CA  1 
ATOM   2870 C C   . ALA B 2 159 ? 41.048  19.568  -78.747 1.00 52.18  ? 153 ALA L C   1 
ATOM   2871 O O   . ALA B 2 159 ? 41.394  19.902  -77.608 1.00 53.62  ? 153 ALA L O   1 
ATOM   2872 C CB  . ALA B 2 159 ? 43.168  18.580  -79.658 1.00 29.62  ? 153 ALA L CB  1 
ATOM   2873 N N   . LEU B 2 160 ? 39.813  19.176  -79.050 1.00 39.76  ? 154 LEU L N   1 
ATOM   2874 C CA  . LEU B 2 160 ? 38.770  19.135  -78.036 1.00 28.08  ? 154 LEU L CA  1 
ATOM   2875 C C   . LEU B 2 160 ? 39.075  18.058  -77.001 1.00 34.94  ? 154 LEU L C   1 
ATOM   2876 O O   . LEU B 2 160 ? 39.488  16.945  -77.341 1.00 45.15  ? 154 LEU L O   1 
ATOM   2877 C CB  . LEU B 2 160 ? 37.413  18.879  -78.689 1.00 29.72  ? 154 LEU L CB  1 
ATOM   2878 C CG  . LEU B 2 160 ? 36.167  19.052  -77.820 1.00 32.53  ? 154 LEU L CG  1 
ATOM   2879 C CD1 . LEU B 2 160 ? 36.088  20.468  -77.274 1.00 45.20  ? 154 LEU L CD1 1 
ATOM   2880 C CD2 . LEU B 2 160 ? 34.920  18.714  -78.620 1.00 34.80  ? 154 LEU L CD2 1 
ATOM   2881 N N   . GLN B 2 161 ? 38.872  18.395  -75.732 1.00 35.73  ? 155 GLN L N   1 
ATOM   2882 C CA  . GLN B 2 161 ? 39.171  17.500  -74.625 1.00 38.95  ? 155 GLN L CA  1 
ATOM   2883 C C   . GLN B 2 161 ? 37.905  16.800  -74.149 1.00 32.97  ? 155 GLN L C   1 
ATOM   2884 O O   . GLN B 2 161 ? 36.810  17.368  -74.175 1.00 42.06  ? 155 GLN L O   1 
ATOM   2885 C CB  . GLN B 2 161 ? 39.813  18.265  -73.465 1.00 40.61  ? 155 GLN L CB  1 
ATOM   2886 C CG  . GLN B 2 161 ? 41.079  19.017  -73.845 1.00 45.06  ? 155 GLN L CG  1 
ATOM   2887 C CD  . GLN B 2 161 ? 42.173  18.101  -74.361 1.00 42.06  ? 155 GLN L CD  1 
ATOM   2888 O OE1 . GLN B 2 161 ? 42.682  17.250  -73.632 1.00 47.94  ? 155 GLN L OE1 1 
ATOM   2889 N NE2 . GLN B 2 161 ? 42.537  18.269  -75.627 1.00 36.15  ? 155 GLN L NE2 1 
ATOM   2890 N N   . SER B 2 162 ? 38.067  15.553  -73.711 1.00 31.81  ? 156 SER L N   1 
ATOM   2891 C CA  . SER B 2 162 ? 36.938  14.735  -73.287 1.00 29.78  ? 156 SER L CA  1 
ATOM   2892 C C   . SER B 2 162 ? 37.361  13.837  -72.134 1.00 36.60  ? 156 SER L C   1 
ATOM   2893 O O   . SER B 2 162 ? 38.392  13.164  -72.215 1.00 37.25  ? 156 SER L O   1 
ATOM   2894 C CB  . SER B 2 162 ? 36.408  13.891  -74.451 1.00 36.88  ? 156 SER L CB  1 
ATOM   2895 O OG  . SER B 2 162 ? 35.384  13.010  -74.024 1.00 45.68  ? 156 SER L OG  1 
ATOM   2896 N N   . GLY B 2 163 ? 36.561  13.832  -71.068 1.00 40.44  ? 157 GLY L N   1 
ATOM   2897 C CA  . GLY B 2 163 ? 36.784  12.944  -69.944 1.00 36.27  ? 157 GLY L CA  1 
ATOM   2898 C C   . GLY B 2 163 ? 37.864  13.369  -68.977 1.00 33.39  ? 157 GLY L C   1 
ATOM   2899 O O   . GLY B 2 163 ? 38.194  12.597  -68.069 1.00 43.49  ? 157 GLY L O   1 
ATOM   2900 N N   . ASN B 2 164 ? 38.428  14.568  -69.136 1.00 28.70  ? 158 ASN L N   1 
ATOM   2901 C CA  . ASN B 2 164 ? 39.481  15.051  -68.252 1.00 27.22  ? 158 ASN L CA  1 
ATOM   2902 C C   . ASN B 2 164 ? 39.139  16.406  -67.644 1.00 37.17  ? 158 ASN L C   1 
ATOM   2903 O O   . ASN B 2 164 ? 40.042  17.129  -67.208 1.00 47.65  ? 158 ASN L O   1 
ATOM   2904 C CB  . ASN B 2 164 ? 40.817  15.128  -68.995 1.00 33.32  ? 158 ASN L CB  1 
ATOM   2905 C CG  . ASN B 2 164 ? 40.709  15.874  -70.311 1.00 28.14  ? 158 ASN L CG  1 
ATOM   2906 O OD1 . ASN B 2 164 ? 39.667  16.448  -70.633 1.00 35.30  ? 158 ASN L OD1 1 
ATOM   2907 N ND2 . ASN B 2 164 ? 41.792  15.874  -71.079 1.00 41.03  ? 158 ASN L ND2 1 
ATOM   2908 N N   . SER B 2 165 ? 37.860  16.769  -67.610 1.00 33.47  ? 159 SER L N   1 
ATOM   2909 C CA  . SER B 2 165 ? 37.442  18.052  -67.067 1.00 38.96  ? 159 SER L CA  1 
ATOM   2910 C C   . SER B 2 165 ? 36.237  17.859  -66.162 1.00 43.08  ? 159 SER L C   1 
ATOM   2911 O O   . SER B 2 165 ? 35.325  17.092  -66.484 1.00 48.38  ? 159 SER L O   1 
ATOM   2912 C CB  . SER B 2 165 ? 37.105  19.050  -68.183 1.00 36.73  ? 159 SER L CB  1 
ATOM   2913 O OG  . SER B 2 165 ? 36.045  18.571  -68.992 1.00 38.86  ? 159 SER L OG  1 
ATOM   2914 N N   . GLN B 2 166 ? 36.239  18.563  -65.032 1.00 36.24  ? 160 GLN L N   1 
ATOM   2915 C CA  . GLN B 2 166 ? 35.133  18.560  -64.089 1.00 27.61  ? 160 GLN L CA  1 
ATOM   2916 C C   . GLN B 2 166 ? 34.664  19.989  -63.855 1.00 26.93  ? 160 GLN L C   1 
ATOM   2917 O O   . GLN B 2 166 ? 35.415  20.952  -64.034 1.00 31.49  ? 160 GLN L O   1 
ATOM   2918 C CB  . GLN B 2 166 ? 35.526  17.897  -62.762 1.00 29.39  ? 160 GLN L CB  1 
ATOM   2919 C CG  . GLN B 2 166 ? 35.481  16.376  -62.805 1.00 47.47  ? 160 GLN L CG  1 
ATOM   2920 C CD  . GLN B 2 166 ? 35.934  15.737  -61.509 1.00 74.82  ? 160 GLN L CD  1 
ATOM   2921 O OE1 . GLN B 2 166 ? 35.508  14.634  -61.163 1.00 73.87  ? 160 GLN L OE1 1 
ATOM   2922 N NE2 . GLN B 2 166 ? 36.809  16.427  -60.785 1.00 60.64  ? 160 GLN L NE2 1 
ATOM   2923 N N   . GLU B 2 167 ? 33.401  20.116  -63.457 1.00 29.06  ? 161 GLU L N   1 
ATOM   2924 C CA  . GLU B 2 167 ? 32.724  21.403  -63.414 1.00 29.44  ? 161 GLU L CA  1 
ATOM   2925 C C   . GLU B 2 167 ? 31.969  21.557  -62.101 1.00 27.87  ? 161 GLU L C   1 
ATOM   2926 O O   . GLU B 2 167 ? 31.449  20.586  -61.543 1.00 26.41  ? 161 GLU L O   1 
ATOM   2927 C CB  . GLU B 2 167 ? 31.771  21.535  -64.608 1.00 35.70  ? 161 GLU L CB  1 
ATOM   2928 C CG  . GLU B 2 167 ? 31.089  22.875  -64.767 1.00 54.02  ? 161 GLU L CG  1 
ATOM   2929 C CD  . GLU B 2 167 ? 30.307  22.956  -66.064 1.00 66.56  ? 161 GLU L CD  1 
ATOM   2930 O OE1 . GLU B 2 167 ? 30.943  23.076  -67.134 1.00 56.60  ? 161 GLU L OE1 1 
ATOM   2931 O OE2 . GLU B 2 167 ? 29.061  22.873  -66.016 1.00 56.92  ? 161 GLU L OE2 1 
ATOM   2932 N N   . SER B 2 168 ? 31.915  22.794  -61.610 1.00 23.29  ? 162 SER L N   1 
ATOM   2933 C CA  . SER B 2 168 ? 31.256  23.097  -60.349 1.00 23.88  ? 162 SER L CA  1 
ATOM   2934 C C   . SER B 2 168 ? 30.683  24.505  -60.415 1.00 29.89  ? 162 SER L C   1 
ATOM   2935 O O   . SER B 2 168 ? 31.338  25.426  -60.910 1.00 32.63  ? 162 SER L O   1 
ATOM   2936 C CB  . SER B 2 168 ? 32.229  22.968  -59.172 1.00 17.61  ? 162 SER L CB  1 
ATOM   2937 O OG  . SER B 2 168 ? 31.554  23.098  -57.935 1.00 28.56  ? 162 SER L OG  1 
ATOM   2938 N N   . VAL B 2 169 ? 29.459  24.664  -59.915 1.00 25.63  ? 163 VAL L N   1 
ATOM   2939 C CA  . VAL B 2 169 ? 28.728  25.924  -59.986 1.00 27.48  ? 163 VAL L CA  1 
ATOM   2940 C C   . VAL B 2 169 ? 28.339  26.349  -58.577 1.00 38.76  ? 163 VAL L C   1 
ATOM   2941 O O   . VAL B 2 169 ? 27.993  25.510  -57.739 1.00 48.01  ? 163 VAL L O   1 
ATOM   2942 C CB  . VAL B 2 169 ? 27.472  25.806  -60.875 1.00 16.44  ? 163 VAL L CB  1 
ATOM   2943 C CG1 . VAL B 2 169 ? 27.025  27.181  -61.349 1.00 21.14  ? 163 VAL L CG1 1 
ATOM   2944 C CG2 . VAL B 2 169 ? 27.726  24.874  -62.051 1.00 38.08  ? 163 VAL L CG2 1 
ATOM   2945 N N   . THR B 2 170 ? 28.400  27.653  -58.320 1.00 28.74  ? 164 THR L N   1 
ATOM   2946 C CA  . THR B 2 170 ? 27.944  28.191  -57.049 1.00 35.90  ? 164 THR L CA  1 
ATOM   2947 C C   . THR B 2 170 ? 26.433  28.410  -57.069 1.00 41.90  ? 164 THR L C   1 
ATOM   2948 O O   . THR B 2 170 ? 25.793  28.434  -58.124 1.00 42.66  ? 164 THR L O   1 
ATOM   2949 C CB  . THR B 2 170 ? 28.642  29.515  -56.727 1.00 31.63  ? 164 THR L CB  1 
ATOM   2950 O OG1 . THR B 2 170 ? 28.270  30.503  -57.696 1.00 32.38  ? 164 THR L OG1 1 
ATOM   2951 C CG2 . THR B 2 170 ? 30.150  29.344  -56.738 1.00 36.14  ? 164 THR L CG2 1 
ATOM   2952 N N   . GLU B 2 171 ? 25.866  28.568  -55.876 1.00 43.91  ? 165 GLU L N   1 
ATOM   2953 C CA  . GLU B 2 171 ? 24.473  28.961  -55.759 1.00 39.92  ? 165 GLU L CA  1 
ATOM   2954 C C   . GLU B 2 171 ? 24.322  30.434  -56.137 1.00 45.38  ? 165 GLU L C   1 
ATOM   2955 O O   . GLU B 2 171 ? 25.303  31.168  -56.294 1.00 54.51  ? 165 GLU L O   1 
ATOM   2956 C CB  . GLU B 2 171 ? 23.963  28.713  -54.338 1.00 44.04  ? 165 GLU L CB  1 
ATOM   2957 C CG  . GLU B 2 171 ? 22.486  28.356  -54.254 1.00 69.08  ? 165 GLU L CG  1 
ATOM   2958 C CD  . GLU B 2 171 ? 22.206  26.923  -54.667 1.00 79.17  ? 165 GLU L CD  1 
ATOM   2959 O OE1 . GLU B 2 171 ? 22.873  26.009  -54.135 1.00 64.71  ? 165 GLU L OE1 1 
ATOM   2960 O OE2 . GLU B 2 171 ? 21.326  26.711  -55.529 1.00 77.50  ? 165 GLU L OE2 1 
ATOM   2961 N N   . GLN B 2 172 ? 23.073  30.867  -56.296 1.00 42.39  ? 166 GLN L N   1 
ATOM   2962 C CA  . GLN B 2 172 ? 22.815  32.257  -56.645 1.00 33.72  ? 166 GLN L CA  1 
ATOM   2963 C C   . GLN B 2 172 ? 23.245  33.165  -55.500 1.00 36.94  ? 166 GLN L C   1 
ATOM   2964 O O   . GLN B 2 172 ? 22.818  32.984  -54.356 1.00 51.58  ? 166 GLN L O   1 
ATOM   2965 C CB  . GLN B 2 172 ? 21.336  32.463  -56.966 1.00 28.13  ? 166 GLN L CB  1 
ATOM   2966 C CG  . GLN B 2 172 ? 21.036  33.796  -57.630 1.00 24.16  ? 166 GLN L CG  1 
ATOM   2967 C CD  . GLN B 2 172 ? 19.578  33.948  -58.012 1.00 40.76  ? 166 GLN L CD  1 
ATOM   2968 O OE1 . GLN B 2 172 ? 18.687  33.465  -57.314 1.00 49.01  ? 166 GLN L OE1 1 
ATOM   2969 N NE2 . GLN B 2 172 ? 19.328  34.621  -59.130 1.00 45.39  ? 166 GLN L NE2 1 
ATOM   2970 N N   . ASP B 2 173 ? 24.099  34.138  -55.811 1.00 35.73  ? 167 ASP L N   1 
ATOM   2971 C CA  . ASP B 2 173 ? 24.647  35.009  -54.781 1.00 51.67  ? 167 ASP L CA  1 
ATOM   2972 C C   . ASP B 2 173 ? 23.541  35.848  -54.151 1.00 58.35  ? 167 ASP L C   1 
ATOM   2973 O O   . ASP B 2 173 ? 22.589  36.258  -54.821 1.00 61.08  ? 167 ASP L O   1 
ATOM   2974 C CB  . ASP B 2 173 ? 25.735  35.904  -55.374 1.00 53.99  ? 167 ASP L CB  1 
ATOM   2975 C CG  . ASP B 2 173 ? 26.555  36.619  -54.314 1.00 65.19  ? 167 ASP L CG  1 
ATOM   2976 O OD1 . ASP B 2 173 ? 26.259  36.456  -53.111 1.00 71.02  ? 167 ASP L OD1 1 
ATOM   2977 O OD2 . ASP B 2 173 ? 27.503  37.342  -54.686 1.00 63.67  ? 167 ASP L OD2 1 
ATOM   2978 N N   . SER B 2 174 ? 23.675  36.100  -52.847 1.00 54.63  ? 168 SER L N   1 
ATOM   2979 C CA  . SER B 2 174 ? 22.592  36.713  -52.084 1.00 55.69  ? 168 SER L CA  1 
ATOM   2980 C C   . SER B 2 174 ? 22.385  38.187  -52.406 1.00 61.21  ? 168 SER L C   1 
ATOM   2981 O O   . SER B 2 174 ? 21.333  38.733  -52.057 1.00 61.16  ? 168 SER L O   1 
ATOM   2982 C CB  . SER B 2 174 ? 22.845  36.549  -50.584 1.00 56.81  ? 168 SER L CB  1 
ATOM   2983 O OG  . SER B 2 174 ? 22.363  35.300  -50.117 1.00 73.65  ? 168 SER L OG  1 
ATOM   2984 N N   . LYS B 2 175 ? 23.343  38.849  -53.055 1.00 60.44  ? 169 LYS L N   1 
ATOM   2985 C CA  . LYS B 2 175 ? 23.242  40.284  -53.294 1.00 49.33  ? 169 LYS L CA  1 
ATOM   2986 C C   . LYS B 2 175 ? 23.025  40.627  -54.764 1.00 54.03  ? 169 LYS L C   1 
ATOM   2987 O O   . LYS B 2 175 ? 22.049  41.304  -55.098 1.00 60.58  ? 169 LYS L O   1 
ATOM   2988 C CB  . LYS B 2 175 ? 24.486  41.003  -52.747 1.00 57.27  ? 169 LYS L CB  1 
ATOM   2989 C CG  . LYS B 2 175 ? 25.819  40.400  -53.157 1.00 66.24  ? 169 LYS L CG  1 
ATOM   2990 C CD  . LYS B 2 175 ? 26.979  41.245  -52.651 1.00 70.40  ? 169 LYS L CD  1 
ATOM   2991 C CE  . LYS B 2 175 ? 26.874  42.682  -53.144 1.00 65.86  ? 169 LYS L CE  1 
ATOM   2992 N NZ  . LYS B 2 175 ? 26.880  42.764  -54.631 1.00 53.77  ? 169 LYS L NZ  1 
ATOM   2993 N N   . ASP B 2 176 ? 23.902  40.179  -55.660 1.00 53.97  ? 170 ASP L N   1 
ATOM   2994 C CA  . ASP B 2 176 ? 23.802  40.525  -57.073 1.00 47.05  ? 170 ASP L CA  1 
ATOM   2995 C C   . ASP B 2 176 ? 23.066  39.477  -57.898 1.00 56.45  ? 170 ASP L C   1 
ATOM   2996 O O   . ASP B 2 176 ? 22.917  39.660  -59.111 1.00 49.63  ? 170 ASP L O   1 
ATOM   2997 C CB  . ASP B 2 176 ? 25.199  40.766  -57.658 1.00 51.70  ? 170 ASP L CB  1 
ATOM   2998 C CG  . ASP B 2 176 ? 26.194  39.699  -57.253 1.00 70.61  ? 170 ASP L CG  1 
ATOM   2999 O OD1 . ASP B 2 176 ? 25.776  38.713  -56.616 1.00 73.82  ? 170 ASP L OD1 1 
ATOM   3000 O OD2 . ASP B 2 176 ? 27.395  39.849  -57.564 1.00 62.48  ? 170 ASP L OD2 1 
ATOM   3001 N N   . SER B 2 177 ? 22.600  38.393  -57.271 1.00 56.39  ? 171 SER L N   1 
ATOM   3002 C CA  . SER B 2 177 ? 21.786  37.371  -57.935 1.00 46.24  ? 171 SER L CA  1 
ATOM   3003 C C   . SER B 2 177 ? 22.493  36.788  -59.157 1.00 42.57  ? 171 SER L C   1 
ATOM   3004 O O   . SER B 2 177 ? 21.872  36.522  -60.188 1.00 44.32  ? 171 SER L O   1 
ATOM   3005 C CB  . SER B 2 177 ? 20.411  37.926  -58.318 1.00 45.07  ? 171 SER L CB  1 
ATOM   3006 O OG  . SER B 2 177 ? 19.729  38.430  -57.182 1.00 47.95  ? 171 SER L OG  1 
ATOM   3007 N N   . THR B 2 178 ? 23.801  36.585  -59.043 1.00 43.43  ? 172 THR L N   1 
ATOM   3008 C CA  . THR B 2 178 ? 24.612  36.054  -60.127 1.00 48.22  ? 172 THR L CA  1 
ATOM   3009 C C   . THR B 2 178 ? 25.099  34.651  -59.789 1.00 40.43  ? 172 THR L C   1 
ATOM   3010 O O   . THR B 2 178 ? 24.990  34.179  -58.654 1.00 31.49  ? 172 THR L O   1 
ATOM   3011 C CB  . THR B 2 178 ? 25.808  36.969  -60.419 1.00 48.08  ? 172 THR L CB  1 
ATOM   3012 O OG1 . THR B 2 178 ? 26.600  37.116  -59.234 1.00 55.74  ? 172 THR L OG1 1 
ATOM   3013 C CG2 . THR B 2 178 ? 25.335  38.338  -60.884 1.00 37.51  ? 172 THR L CG2 1 
ATOM   3014 N N   . TYR B 2 179 ? 25.642  33.986  -60.804 1.00 39.27  ? 173 TYR L N   1 
ATOM   3015 C CA  . TYR B 2 179 ? 26.208  32.654  -60.668 1.00 38.10  ? 173 TYR L CA  1 
ATOM   3016 C C   . TYR B 2 179 ? 27.679  32.681  -61.060 1.00 34.48  ? 173 TYR L C   1 
ATOM   3017 O O   . TYR B 2 179 ? 28.106  33.508  -61.870 1.00 35.51  ? 173 TYR L O   1 
ATOM   3018 C CB  . TYR B 2 179 ? 25.457  31.634  -61.537 1.00 31.05  ? 173 TYR L CB  1 
ATOM   3019 C CG  . TYR B 2 179 ? 24.016  31.418  -61.135 1.00 25.68  ? 173 TYR L CG  1 
ATOM   3020 C CD1 . TYR B 2 179 ? 23.685  30.542  -60.109 1.00 31.45  ? 173 TYR L CD1 1 
ATOM   3021 C CD2 . TYR B 2 179 ? 22.984  32.085  -61.785 1.00 27.72  ? 173 TYR L CD2 1 
ATOM   3022 C CE1 . TYR B 2 179 ? 22.370  30.339  -59.738 1.00 41.45  ? 173 TYR L CE1 1 
ATOM   3023 C CE2 . TYR B 2 179 ? 21.665  31.889  -61.421 1.00 26.11  ? 173 TYR L CE2 1 
ATOM   3024 C CZ  . TYR B 2 179 ? 21.364  31.015  -60.397 1.00 41.19  ? 173 TYR L CZ  1 
ATOM   3025 O OH  . TYR B 2 179 ? 20.052  30.814  -60.031 1.00 54.36  ? 173 TYR L OH  1 
ATOM   3026 N N   . SER B 2 180 ? 28.454  31.774  -60.472 1.00 35.10  ? 174 SER L N   1 
ATOM   3027 C CA  . SER B 2 180 ? 29.863  31.619  -60.801 1.00 25.71  ? 174 SER L CA  1 
ATOM   3028 C C   . SER B 2 180 ? 30.157  30.155  -61.084 1.00 29.42  ? 174 SER L C   1 
ATOM   3029 O O   . SER B 2 180 ? 29.647  29.266  -60.395 1.00 29.54  ? 174 SER L O   1 
ATOM   3030 C CB  . SER B 2 180 ? 30.766  32.132  -59.674 1.00 42.01  ? 174 SER L CB  1 
ATOM   3031 O OG  . SER B 2 180 ? 30.858  33.546  -59.701 1.00 50.76  ? 174 SER L OG  1 
ATOM   3032 N N   . LEU B 2 181 ? 30.983  29.910  -62.099 1.00 34.51  ? 175 LEU L N   1 
ATOM   3033 C CA  . LEU B 2 181 ? 31.288  28.562  -62.555 1.00 31.60  ? 175 LEU L CA  1 
ATOM   3034 C C   . LEU B 2 181 ? 32.795  28.365  -62.611 1.00 34.23  ? 175 LEU L C   1 
ATOM   3035 O O   . LEU B 2 181 ? 33.542  29.291  -62.941 1.00 32.57  ? 175 LEU L O   1 
ATOM   3036 C CB  . LEU B 2 181 ? 30.666  28.296  -63.937 1.00 22.85  ? 175 LEU L CB  1 
ATOM   3037 C CG  . LEU B 2 181 ? 30.803  26.901  -64.555 1.00 34.25  ? 175 LEU L CG  1 
ATOM   3038 C CD1 . LEU B 2 181 ? 29.543  26.549  -65.326 1.00 34.00  ? 175 LEU L CD1 1 
ATOM   3039 C CD2 . LEU B 2 181 ? 32.018  26.815  -65.469 1.00 34.20  ? 175 LEU L CD2 1 
ATOM   3040 N N   . SER B 2 182 ? 33.236  27.152  -62.285 1.00 31.85  ? 176 SER L N   1 
ATOM   3041 C CA  . SER B 2 182 ? 34.636  26.766  -62.389 1.00 22.74  ? 176 SER L CA  1 
ATOM   3042 C C   . SER B 2 182 ? 34.726  25.440  -63.126 1.00 38.05  ? 176 SER L C   1 
ATOM   3043 O O   . SER B 2 182 ? 34.026  24.483  -62.777 1.00 36.78  ? 176 SER L O   1 
ATOM   3044 C CB  . SER B 2 182 ? 35.292  26.648  -61.010 1.00 29.05  ? 176 SER L CB  1 
ATOM   3045 O OG  . SER B 2 182 ? 34.766  25.550  -60.286 1.00 38.22  ? 176 SER L OG  1 
ATOM   3046 N N   . SER B 2 183 ? 35.580  25.387  -64.145 1.00 41.37  ? 177 SER L N   1 
ATOM   3047 C CA  . SER B 2 183 ? 35.834  24.168  -64.902 1.00 39.74  ? 177 SER L CA  1 
ATOM   3048 C C   . SER B 2 183 ? 37.323  23.868  -64.827 1.00 32.37  ? 177 SER L C   1 
ATOM   3049 O O   . SER B 2 183 ? 38.147  24.703  -65.215 1.00 39.27  ? 177 SER L O   1 
ATOM   3050 C CB  . SER B 2 183 ? 35.378  24.317  -66.355 1.00 29.51  ? 177 SER L CB  1 
ATOM   3051 O OG  . SER B 2 183 ? 35.439  23.077  -67.039 1.00 46.33  ? 177 SER L OG  1 
ATOM   3052 N N   . THR B 2 184 ? 37.666  22.683  -64.329 1.00 31.94  ? 178 THR L N   1 
ATOM   3053 C CA  . THR B 2 184 ? 39.052  22.303  -64.090 1.00 31.12  ? 178 THR L CA  1 
ATOM   3054 C C   . THR B 2 184 ? 39.447  21.192  -65.052 1.00 38.63  ? 178 THR L C   1 
ATOM   3055 O O   . THR B 2 184 ? 38.823  20.126  -65.067 1.00 43.41  ? 178 THR L O   1 
ATOM   3056 C CB  . THR B 2 184 ? 39.257  21.852  -62.644 1.00 24.80  ? 178 THR L CB  1 
ATOM   3057 O OG1 . THR B 2 184 ? 38.908  22.919  -61.753 1.00 34.90  ? 178 THR L OG1 1 
ATOM   3058 C CG2 . THR B 2 184 ? 40.707  21.458  -62.410 1.00 28.61  ? 178 THR L CG2 1 
ATOM   3059 N N   . LEU B 2 185 ? 40.486  21.443  -65.844 1.00 32.72  ? 179 LEU L N   1 
ATOM   3060 C CA  . LEU B 2 185 ? 41.075  20.442  -66.722 1.00 33.82  ? 179 LEU L CA  1 
ATOM   3061 C C   . LEU B 2 185 ? 42.289  19.840  -66.030 1.00 41.26  ? 179 LEU L C   1 
ATOM   3062 O O   . LEU B 2 185 ? 43.171  20.573  -65.573 1.00 50.32  ? 179 LEU L O   1 
ATOM   3063 C CB  . LEU B 2 185 ? 41.483  21.064  -68.058 1.00 29.10  ? 179 LEU L CB  1 
ATOM   3064 C CG  . LEU B 2 185 ? 42.107  20.110  -69.076 1.00 32.69  ? 179 LEU L CG  1 
ATOM   3065 C CD1 . LEU B 2 185 ? 41.034  19.262  -69.731 1.00 36.10  ? 179 LEU L CD1 1 
ATOM   3066 C CD2 . LEU B 2 185 ? 42.912  20.871  -70.118 1.00 36.14  ? 179 LEU L CD2 1 
ATOM   3067 N N   . THR B 2 186 ? 42.335  18.512  -65.955 1.00 39.72  ? 180 THR L N   1 
ATOM   3068 C CA  . THR B 2 186 ? 43.382  17.810  -65.224 1.00 46.54  ? 180 THR L CA  1 
ATOM   3069 C C   . THR B 2 186 ? 44.096  16.837  -66.152 1.00 45.76  ? 180 THR L C   1 
ATOM   3070 O O   . THR B 2 186 ? 43.456  15.987  -66.780 1.00 47.86  ? 180 THR L O   1 
ATOM   3071 C CB  . THR B 2 186 ? 42.807  17.068  -64.017 1.00 57.33  ? 180 THR L CB  1 
ATOM   3072 O OG1 . THR B 2 186 ? 41.811  17.884  -63.388 1.00 53.60  ? 180 THR L OG1 1 
ATOM   3073 C CG2 . THR B 2 186 ? 43.907  16.768  -63.011 1.00 48.87  ? 180 THR L CG2 1 
ATOM   3074 N N   . LEU B 2 187 ? 45.418  16.964  -66.224 1.00 47.79  ? 181 LEU L N   1 
ATOM   3075 C CA  . LEU B 2 187 ? 46.257  16.105  -67.043 1.00 41.57  ? 181 LEU L CA  1 
ATOM   3076 C C   . LEU B 2 187 ? 47.485  15.702  -66.241 1.00 44.05  ? 181 LEU L C   1 
ATOM   3077 O O   . LEU B 2 187 ? 47.844  16.345  -65.252 1.00 54.97  ? 181 LEU L O   1 
ATOM   3078 C CB  . LEU B 2 187 ? 46.695  16.805  -68.338 1.00 38.38  ? 181 LEU L CB  1 
ATOM   3079 C CG  . LEU B 2 187 ? 45.672  16.990  -69.457 1.00 53.26  ? 181 LEU L CG  1 
ATOM   3080 C CD1 . LEU B 2 187 ? 46.039  18.199  -70.302 1.00 34.86  ? 181 LEU L CD1 1 
ATOM   3081 C CD2 . LEU B 2 187 ? 45.607  15.740  -70.318 1.00 60.80  ? 181 LEU L CD2 1 
ATOM   3082 N N   . SER B 2 188 ? 48.126  14.619  -66.673 1.00 55.74  ? 182 SER L N   1 
ATOM   3083 C CA  . SER B 2 188 ? 49.429  14.282  -66.126 1.00 59.52  ? 182 SER L CA  1 
ATOM   3084 C C   . SER B 2 188 ? 50.471  15.275  -66.633 1.00 61.71  ? 182 SER L C   1 
ATOM   3085 O O   . SER B 2 188 ? 50.292  15.930  -67.664 1.00 58.56  ? 182 SER L O   1 
ATOM   3086 C CB  . SER B 2 188 ? 49.828  12.855  -66.504 1.00 52.89  ? 182 SER L CB  1 
ATOM   3087 O OG  . SER B 2 188 ? 50.359  12.804  -67.816 1.00 57.08  ? 182 SER L OG  1 
ATOM   3088 N N   . LYS B 2 189 ? 51.572  15.390  -65.887 1.00 60.23  ? 183 LYS L N   1 
ATOM   3089 C CA  . LYS B 2 189 ? 52.603  16.356  -66.255 1.00 58.30  ? 183 LYS L CA  1 
ATOM   3090 C C   . LYS B 2 189 ? 53.229  16.013  -67.601 1.00 54.33  ? 183 LYS L C   1 
ATOM   3091 O O   . LYS B 2 189 ? 53.590  16.910  -68.372 1.00 60.32  ? 183 LYS L O   1 
ATOM   3092 C CB  . LYS B 2 189 ? 53.677  16.427  -65.171 1.00 59.94  ? 183 LYS L CB  1 
ATOM   3093 C CG  . LYS B 2 189 ? 54.682  17.547  -65.391 1.00 57.03  ? 183 LYS L CG  1 
ATOM   3094 C CD  . LYS B 2 189 ? 55.840  17.465  -64.415 1.00 67.18  ? 183 LYS L CD  1 
ATOM   3095 C CE  . LYS B 2 189 ? 56.668  16.215  -64.647 1.00 70.18  ? 183 LYS L CE  1 
ATOM   3096 N NZ  . LYS B 2 189 ? 57.805  16.120  -63.691 1.00 68.24  ? 183 LYS L NZ  1 
ATOM   3097 N N   . ALA B 2 190 ? 53.371  14.720  -67.899 1.00 41.00  ? 184 ALA L N   1 
ATOM   3098 C CA  . ALA B 2 190 ? 53.944  14.313  -69.177 1.00 51.42  ? 184 ALA L CA  1 
ATOM   3099 C C   . ALA B 2 190 ? 53.078  14.777  -70.341 1.00 63.44  ? 184 ALA L C   1 
ATOM   3100 O O   . ALA B 2 190 ? 53.581  15.345  -71.318 1.00 67.27  ? 184 ALA L O   1 
ATOM   3101 C CB  . ALA B 2 190 ? 54.124  12.795  -69.210 1.00 66.85  ? 184 ALA L CB  1 
ATOM   3102 N N   . ASP B 2 191 ? 51.764  14.555  -70.249 1.00 58.01  ? 185 ASP L N   1 
ATOM   3103 C CA  . ASP B 2 191 ? 50.868  14.985  -71.317 1.00 55.34  ? 185 ASP L CA  1 
ATOM   3104 C C   . ASP B 2 191 ? 50.734  16.501  -71.358 1.00 54.84  ? 185 ASP L C   1 
ATOM   3105 O O   . ASP B 2 191 ? 50.495  17.072  -72.429 1.00 54.58  ? 185 ASP L O   1 
ATOM   3106 C CB  . ASP B 2 191 ? 49.494  14.336  -71.147 1.00 61.20  ? 185 ASP L CB  1 
ATOM   3107 C CG  . ASP B 2 191 ? 49.573  12.826  -71.024 1.00 79.15  ? 185 ASP L CG  1 
ATOM   3108 O OD1 . ASP B 2 191 ? 49.857  12.333  -69.912 1.00 93.32  ? 185 ASP L OD1 1 
ATOM   3109 O OD2 . ASP B 2 191 ? 49.354  12.130  -72.038 1.00 78.77  ? 185 ASP L OD2 1 
ATOM   3110 N N   . TYR B 2 192 ? 50.880  17.167  -70.209 1.00 50.69  ? 186 TYR L N   1 
ATOM   3111 C CA  . TYR B 2 192 ? 50.774  18.622  -70.178 1.00 46.85  ? 186 TYR L CA  1 
ATOM   3112 C C   . TYR B 2 192 ? 51.902  19.279  -70.965 1.00 61.07  ? 186 TYR L C   1 
ATOM   3113 O O   . TYR B 2 192 ? 51.687  20.288  -71.647 1.00 52.97  ? 186 TYR L O   1 
ATOM   3114 C CB  . TYR B 2 192 ? 50.766  19.118  -68.732 1.00 42.04  ? 186 TYR L CB  1 
ATOM   3115 C CG  . TYR B 2 192 ? 50.738  20.625  -68.601 1.00 48.30  ? 186 TYR L CG  1 
ATOM   3116 C CD1 . TYR B 2 192 ? 49.565  21.339  -68.814 1.00 45.45  ? 186 TYR L CD1 1 
ATOM   3117 C CD2 . TYR B 2 192 ? 51.882  21.333  -68.257 1.00 50.01  ? 186 TYR L CD2 1 
ATOM   3118 C CE1 . TYR B 2 192 ? 49.534  22.717  -68.693 1.00 38.41  ? 186 TYR L CE1 1 
ATOM   3119 C CE2 . TYR B 2 192 ? 51.861  22.710  -68.134 1.00 51.96  ? 186 TYR L CE2 1 
ATOM   3120 C CZ  . TYR B 2 192 ? 50.685  23.396  -68.353 1.00 49.48  ? 186 TYR L CZ  1 
ATOM   3121 O OH  . TYR B 2 192 ? 50.661  24.767  -68.231 1.00 42.99  ? 186 TYR L OH  1 
ATOM   3122 N N   . GLU B 2 193 ? 53.109  18.719  -70.891 1.00 70.66  ? 187 GLU L N   1 
ATOM   3123 C CA  . GLU B 2 193 ? 54.262  19.302  -71.565 1.00 68.06  ? 187 GLU L CA  1 
ATOM   3124 C C   . GLU B 2 193 ? 54.374  18.893  -73.029 1.00 59.43  ? 187 GLU L C   1 
ATOM   3125 O O   . GLU B 2 193 ? 55.303  19.344  -73.708 1.00 58.51  ? 187 GLU L O   1 
ATOM   3126 C CB  . GLU B 2 193 ? 55.550  18.932  -70.825 1.00 68.26  ? 187 GLU L CB  1 
ATOM   3127 C CG  . GLU B 2 193 ? 55.883  19.869  -69.675 1.00 65.64  ? 187 GLU L CG  1 
ATOM   3128 C CD  . GLU B 2 193 ? 57.098  19.419  -68.888 1.00 97.68  ? 187 GLU L CD  1 
ATOM   3129 O OE1 . GLU B 2 193 ? 57.761  20.279  -68.270 1.00 112.63 ? 187 GLU L OE1 1 
ATOM   3130 O OE2 . GLU B 2 193 ? 57.391  18.205  -68.888 1.00 104.18 ? 187 GLU L OE2 1 
ATOM   3131 N N   . LYS B 2 194 ? 53.465  18.062  -73.531 1.00 54.67  ? 188 LYS L N   1 
ATOM   3132 C CA  . LYS B 2 194 ? 53.448  17.705  -74.943 1.00 58.82  ? 188 LYS L CA  1 
ATOM   3133 C C   . LYS B 2 194 ? 52.677  18.702  -75.797 1.00 60.76  ? 188 LYS L C   1 
ATOM   3134 O O   . LYS B 2 194 ? 52.586  18.511  -77.014 1.00 66.70  ? 188 LYS L O   1 
ATOM   3135 C CB  . LYS B 2 194 ? 52.851  16.307  -75.138 1.00 51.05  ? 188 LYS L CB  1 
ATOM   3136 C CG  . LYS B 2 194 ? 53.665  15.180  -74.530 1.00 64.23  ? 188 LYS L CG  1 
ATOM   3137 C CD  . LYS B 2 194 ? 53.175  13.827  -75.025 1.00 52.04  ? 188 LYS L CD  1 
ATOM   3138 C CE  . LYS B 2 194 ? 51.684  13.655  -74.787 1.00 60.19  ? 188 LYS L CE  1 
ATOM   3139 N NZ  . LYS B 2 194 ? 51.174  12.385  -75.375 1.00 68.69  ? 188 LYS L NZ  1 
ATOM   3140 N N   . HIS B 2 195 ? 52.121  19.753  -75.196 1.00 56.93  ? 189 HIS L N   1 
ATOM   3141 C CA  . HIS B 2 195 ? 51.280  20.697  -75.916 1.00 47.19  ? 189 HIS L CA  1 
ATOM   3142 C C   . HIS B 2 195 ? 51.607  22.116  -75.475 1.00 51.27  ? 189 HIS L C   1 
ATOM   3143 O O   . HIS B 2 195 ? 52.175  22.343  -74.404 1.00 50.23  ? 189 HIS L O   1 
ATOM   3144 C CB  . HIS B 2 195 ? 49.794  20.396  -75.699 1.00 49.96  ? 189 HIS L CB  1 
ATOM   3145 C CG  . HIS B 2 195 ? 49.397  19.009  -76.097 1.00 55.42  ? 189 HIS L CG  1 
ATOM   3146 N ND1 . HIS B 2 195 ? 49.421  17.948  -75.218 1.00 53.12  ? 189 HIS L ND1 1 
ATOM   3147 C CD2 . HIS B 2 195 ? 48.980  18.506  -77.282 1.00 47.98  ? 189 HIS L CD2 1 
ATOM   3148 C CE1 . HIS B 2 195 ? 49.028  16.852  -75.843 1.00 47.91  ? 189 HIS L CE1 1 
ATOM   3149 N NE2 . HIS B 2 195 ? 48.755  17.164  -77.097 1.00 60.92  ? 189 HIS L NE2 1 
ATOM   3150 N N   . LYS B 2 196 ? 51.238  23.075  -76.323 1.00 47.25  ? 190 LYS L N   1 
ATOM   3151 C CA  . LYS B 2 196 ? 51.589  24.475  -76.124 1.00 49.67  ? 190 LYS L CA  1 
ATOM   3152 C C   . LYS B 2 196 ? 50.410  25.345  -75.711 1.00 48.16  ? 190 LYS L C   1 
ATOM   3153 O O   . LYS B 2 196 ? 50.490  26.050  -74.701 1.00 59.92  ? 190 LYS L O   1 
ATOM   3154 C CB  . LYS B 2 196 ? 52.218  25.037  -77.407 1.00 51.65  ? 190 LYS L CB  1 
ATOM   3155 C CG  . LYS B 2 196 ? 52.934  26.359  -77.209 1.00 64.38  ? 190 LYS L CG  1 
ATOM   3156 C CD  . LYS B 2 196 ? 52.999  27.158  -78.499 1.00 68.15  ? 190 LYS L CD  1 
ATOM   3157 C CE  . LYS B 2 196 ? 53.427  28.590  -78.228 1.00 78.71  ? 190 LYS L CE  1 
ATOM   3158 N NZ  . LYS B 2 196 ? 53.160  29.472  -79.397 1.00 52.60  ? 190 LYS L NZ  1 
ATOM   3159 N N   . VAL B 2 197 ? 49.312  25.317  -76.464 1.00 39.77  ? 191 VAL L N   1 
ATOM   3160 C CA  . VAL B 2 197 ? 48.185  26.222  -76.251 1.00 47.85  ? 191 VAL L CA  1 
ATOM   3161 C C   . VAL B 2 197 ? 47.094  25.497  -75.476 1.00 46.81  ? 191 VAL L C   1 
ATOM   3162 O O   . VAL B 2 197 ? 46.680  24.392  -75.852 1.00 46.86  ? 191 VAL L O   1 
ATOM   3163 C CB  . VAL B 2 197 ? 47.644  26.762  -77.587 1.00 41.38  ? 191 VAL L CB  1 
ATOM   3164 C CG1 . VAL B 2 197 ? 46.221  27.279  -77.420 1.00 48.13  ? 191 VAL L CG1 1 
ATOM   3165 C CG2 . VAL B 2 197 ? 48.548  27.865  -78.113 1.00 36.82  ? 191 VAL L CG2 1 
ATOM   3166 N N   . TYR B 2 198 ? 46.629  26.119  -74.395 1.00 51.84  ? 192 TYR L N   1 
ATOM   3167 C CA  . TYR B 2 198 ? 45.522  25.613  -73.590 1.00 45.79  ? 192 TYR L CA  1 
ATOM   3168 C C   . TYR B 2 198 ? 44.419  26.662  -73.599 1.00 50.73  ? 192 TYR L C   1 
ATOM   3169 O O   . TYR B 2 198 ? 44.558  27.721  -72.978 1.00 48.21  ? 192 TYR L O   1 
ATOM   3170 C CB  . TYR B 2 198 ? 45.980  25.293  -72.168 1.00 40.65  ? 192 TYR L CB  1 
ATOM   3171 C CG  . TYR B 2 198 ? 46.879  24.085  -72.110 1.00 51.07  ? 192 TYR L CG  1 
ATOM   3172 C CD1 . TYR B 2 198 ? 48.223  24.180  -72.441 1.00 47.86  ? 192 TYR L CD1 1 
ATOM   3173 C CD2 . TYR B 2 198 ? 46.379  22.843  -71.745 1.00 45.32  ? 192 TYR L CD2 1 
ATOM   3174 C CE1 . TYR B 2 198 ? 49.046  23.075  -72.401 1.00 52.55  ? 192 TYR L CE1 1 
ATOM   3175 C CE2 . TYR B 2 198 ? 47.193  21.732  -71.701 1.00 46.54  ? 192 TYR L CE2 1 
ATOM   3176 C CZ  . TYR B 2 198 ? 48.525  21.855  -72.030 1.00 52.91  ? 192 TYR L CZ  1 
ATOM   3177 O OH  . TYR B 2 198 ? 49.342  20.752  -71.989 1.00 61.03  ? 192 TYR L OH  1 
ATOM   3178 N N   . ALA B 2 199 ? 43.328  26.365  -74.298 1.00 48.04  ? 193 ALA L N   1 
ATOM   3179 C CA  . ALA B 2 199 ? 42.256  27.319  -74.530 1.00 45.28  ? 193 ALA L CA  1 
ATOM   3180 C C   . ALA B 2 199 ? 40.990  26.893  -73.798 1.00 40.29  ? 193 ALA L C   1 
ATOM   3181 O O   . ALA B 2 199 ? 40.610  25.718  -73.823 1.00 39.13  ? 193 ALA L O   1 
ATOM   3182 C CB  . ALA B 2 199 ? 41.967  27.463  -76.027 1.00 54.48  ? 193 ALA L CB  1 
ATOM   3183 N N   . CYS B 2 200 ? 40.350  27.857  -73.143 1.00 52.69  ? 194 CYS L N   1 
ATOM   3184 C CA  . CYS B 2 200 ? 39.058  27.673  -72.496 1.00 42.73  ? 194 CYS L CA  1 
ATOM   3185 C C   . CYS B 2 200 ? 38.021  28.472  -73.273 1.00 46.23  ? 194 CYS L C   1 
ATOM   3186 O O   . CYS B 2 200 ? 38.109  29.703  -73.344 1.00 53.48  ? 194 CYS L O   1 
ATOM   3187 C CB  . CYS B 2 200 ? 39.112  28.121  -71.035 1.00 29.09  ? 194 CYS L CB  1 
ATOM   3188 S SG  . CYS B 2 200 ? 37.511  28.257  -70.209 1.00 72.28  ? 194 CYS L SG  1 
ATOM   3189 N N   . GLU B 2 201 ? 37.047  27.777  -73.854 1.00 44.31  ? 195 GLU L N   1 
ATOM   3190 C CA  . GLU B 2 201 ? 36.025  28.394  -74.690 1.00 42.19  ? 195 GLU L CA  1 
ATOM   3191 C C   . GLU B 2 201 ? 34.718  28.478  -73.915 1.00 46.38  ? 195 GLU L C   1 
ATOM   3192 O O   . GLU B 2 201 ? 34.290  27.494  -73.302 1.00 47.89  ? 195 GLU L O   1 
ATOM   3193 C CB  . GLU B 2 201 ? 35.831  27.607  -75.987 1.00 46.26  ? 195 GLU L CB  1 
ATOM   3194 C CG  . GLU B 2 201 ? 34.916  28.290  -76.989 1.00 55.38  ? 195 GLU L CG  1 
ATOM   3195 C CD  . GLU B 2 201 ? 34.871  27.570  -78.323 1.00 60.37  ? 195 GLU L CD  1 
ATOM   3196 O OE1 . GLU B 2 201 ? 35.784  26.763  -78.596 1.00 55.40  ? 195 GLU L OE1 1 
ATOM   3197 O OE2 . GLU B 2 201 ? 33.920  27.809  -79.097 1.00 55.38  ? 195 GLU L OE2 1 
ATOM   3198 N N   . VAL B 2 202 ? 34.085  29.649  -73.952 1.00 37.84  ? 196 VAL L N   1 
ATOM   3199 C CA  . VAL B 2 202 ? 32.924  29.954  -73.125 1.00 37.58  ? 196 VAL L CA  1 
ATOM   3200 C C   . VAL B 2 202 ? 31.773  30.391  -74.020 1.00 38.40  ? 196 VAL L C   1 
ATOM   3201 O O   . VAL B 2 202 ? 31.960  31.188  -74.945 1.00 45.58  ? 196 VAL L O   1 
ATOM   3202 C CB  . VAL B 2 202 ? 33.244  31.052  -72.089 1.00 46.21  ? 196 VAL L CB  1 
ATOM   3203 C CG1 . VAL B 2 202 ? 32.113  31.178  -71.084 1.00 25.47  ? 196 VAL L CG1 1 
ATOM   3204 C CG2 . VAL B 2 202 ? 34.564  30.762  -71.391 1.00 48.54  ? 196 VAL L CG2 1 
ATOM   3205 N N   . THR B 2 203 ? 30.581  29.865  -73.741 1.00 34.83  ? 197 THR L N   1 
ATOM   3206 C CA  . THR B 2 203 ? 29.356  30.263  -74.423 1.00 34.83  ? 197 THR L CA  1 
ATOM   3207 C C   . THR B 2 203 ? 28.333  30.687  -73.379 1.00 38.38  ? 197 THR L C   1 
ATOM   3208 O O   . THR B 2 203 ? 28.116  29.971  -72.396 1.00 46.83  ? 197 THR L O   1 
ATOM   3209 C CB  . THR B 2 203 ? 28.795  29.120  -75.281 1.00 37.72  ? 197 THR L CB  1 
ATOM   3210 O OG1 . THR B 2 203 ? 29.719  28.805  -76.330 1.00 38.66  ? 197 THR L OG1 1 
ATOM   3211 C CG2 . THR B 2 203 ? 27.456  29.511  -75.892 1.00 35.58  ? 197 THR L CG2 1 
ATOM   3212 N N   . HIS B 2 204 ? 27.710  31.846  -73.586 1.00 33.29  ? 198 HIS L N   1 
ATOM   3213 C CA  . HIS B 2 204 ? 26.697  32.327  -72.657 1.00 33.45  ? 198 HIS L CA  1 
ATOM   3214 C C   . HIS B 2 204 ? 25.707  33.218  -73.395 1.00 48.82  ? 198 HIS L C   1 
ATOM   3215 O O   . HIS B 2 204 ? 25.997  33.752  -74.469 1.00 58.25  ? 198 HIS L O   1 
ATOM   3216 C CB  . HIS B 2 204 ? 27.322  33.082  -71.478 1.00 25.48  ? 198 HIS L CB  1 
ATOM   3217 C CG  . HIS B 2 204 ? 26.359  33.369  -70.368 1.00 26.75  ? 198 HIS L CG  1 
ATOM   3218 N ND1 . HIS B 2 204 ? 25.711  34.578  -70.240 1.00 33.70  ? 198 HIS L ND1 1 
ATOM   3219 C CD2 . HIS B 2 204 ? 25.928  32.600  -69.341 1.00 37.80  ? 198 HIS L CD2 1 
ATOM   3220 C CE1 . HIS B 2 204 ? 24.925  34.544  -69.178 1.00 38.71  ? 198 HIS L CE1 1 
ATOM   3221 N NE2 . HIS B 2 204 ? 25.038  33.354  -68.615 1.00 34.40  ? 198 HIS L NE2 1 
ATOM   3222 N N   . GLN B 2 205 ? 24.524  33.368  -72.791 1.00 50.55  ? 199 GLN L N   1 
ATOM   3223 C CA  . GLN B 2 205 ? 23.467  34.182  -73.385 1.00 47.59  ? 199 GLN L CA  1 
ATOM   3224 C C   . GLN B 2 205 ? 23.866  35.650  -73.474 1.00 50.40  ? 199 GLN L C   1 
ATOM   3225 O O   . GLN B 2 205 ? 23.467  36.346  -74.414 1.00 50.89  ? 199 GLN L O   1 
ATOM   3226 C CB  . GLN B 2 205 ? 22.181  34.024  -72.570 1.00 55.52  ? 199 GLN L CB  1 
ATOM   3227 C CG  . GLN B 2 205 ? 21.022  34.898  -73.019 1.00 50.62  ? 199 GLN L CG  1 
ATOM   3228 C CD  . GLN B 2 205 ? 19.792  34.725  -72.146 1.00 57.45  ? 199 GLN L CD  1 
ATOM   3229 O OE1 . GLN B 2 205 ? 19.652  33.724  -71.442 1.00 59.32  ? 199 GLN L OE1 1 
ATOM   3230 N NE2 . GLN B 2 205 ? 18.896  35.705  -72.184 1.00 45.57  ? 199 GLN L NE2 1 
ATOM   3231 N N   . GLY B 2 206 ? 24.651  36.132  -72.518 1.00 52.46  ? 200 GLY L N   1 
ATOM   3232 C CA  . GLY B 2 206 ? 25.094  37.508  -72.459 1.00 45.55  ? 200 GLY L CA  1 
ATOM   3233 C C   . GLY B 2 206 ? 26.322  37.831  -73.279 1.00 43.29  ? 200 GLY L C   1 
ATOM   3234 O O   . GLY B 2 206 ? 26.811  38.964  -73.220 1.00 45.01  ? 200 GLY L O   1 
ATOM   3235 N N   . LEU B 2 207 ? 26.843  36.875  -74.043 1.00 45.90  ? 201 LEU L N   1 
ATOM   3236 C CA  . LEU B 2 207 ? 27.998  37.088  -74.905 1.00 38.82  ? 201 LEU L CA  1 
ATOM   3237 C C   . LEU B 2 207 ? 27.564  36.982  -76.360 1.00 55.69  ? 201 LEU L C   1 
ATOM   3238 O O   . LEU B 2 207 ? 26.940  35.992  -76.756 1.00 65.10  ? 201 LEU L O   1 
ATOM   3239 C CB  . LEU B 2 207 ? 29.102  36.072  -74.605 1.00 47.52  ? 201 LEU L CB  1 
ATOM   3240 C CG  . LEU B 2 207 ? 29.766  36.180  -73.230 1.00 34.12  ? 201 LEU L CG  1 
ATOM   3241 C CD1 . LEU B 2 207 ? 30.671  34.986  -72.974 1.00 32.58  ? 201 LEU L CD1 1 
ATOM   3242 C CD2 . LEU B 2 207 ? 30.544  37.482  -73.107 1.00 36.88  ? 201 LEU L CD2 1 
ATOM   3243 N N   . SER B 2 208 ? 27.893  38.008  -77.150 1.00 59.91  ? 202 SER L N   1 
ATOM   3244 C CA  . SER B 2 208 ? 27.528  38.001  -78.563 1.00 51.18  ? 202 SER L CA  1 
ATOM   3245 C C   . SER B 2 208 ? 28.210  36.859  -79.305 1.00 65.37  ? 202 SER L C   1 
ATOM   3246 O O   . SER B 2 208 ? 27.589  36.192  -80.140 1.00 77.98  ? 202 SER L O   1 
ATOM   3247 C CB  . SER B 2 208 ? 27.882  39.344  -79.201 1.00 56.99  ? 202 SER L CB  1 
ATOM   3248 O OG  . SER B 2 208 ? 29.262  39.631  -79.048 1.00 70.10  ? 202 SER L OG  1 
ATOM   3249 N N   . SER B 2 209 ? 29.484  36.619  -79.012 1.00 64.75  ? 203 SER L N   1 
ATOM   3250 C CA  . SER B 2 209 ? 30.263  35.555  -79.622 1.00 57.41  ? 203 SER L CA  1 
ATOM   3251 C C   . SER B 2 209 ? 31.021  34.794  -78.546 1.00 54.69  ? 203 SER L C   1 
ATOM   3252 O O   . SER B 2 209 ? 31.314  35.347  -77.480 1.00 53.65  ? 203 SER L O   1 
ATOM   3253 C CB  . SER B 2 209 ? 31.250  36.117  -80.656 1.00 61.37  ? 203 SER L CB  1 
ATOM   3254 O OG  . SER B 2 209 ? 32.002  37.187  -80.113 1.00 77.33  ? 203 SER L OG  1 
ATOM   3255 N N   . PRO B 2 210 ? 31.338  33.521  -78.788 1.00 56.78  ? 204 PRO L N   1 
ATOM   3256 C CA  . PRO B 2 210 ? 32.053  32.726  -77.776 1.00 54.03  ? 204 PRO L CA  1 
ATOM   3257 C C   . PRO B 2 210 ? 33.414  33.319  -77.443 1.00 44.38  ? 204 PRO L C   1 
ATOM   3258 O O   . PRO B 2 210 ? 34.269  33.497  -78.314 1.00 42.81  ? 204 PRO L O   1 
ATOM   3259 C CB  . PRO B 2 210 ? 32.179  31.350  -78.439 1.00 39.80  ? 204 PRO L CB  1 
ATOM   3260 C CG  . PRO B 2 210 ? 31.026  31.289  -79.382 1.00 38.90  ? 204 PRO L CG  1 
ATOM   3261 C CD  . PRO B 2 210 ? 30.876  32.688  -79.912 1.00 50.11  ? 204 PRO L CD  1 
ATOM   3262 N N   . VAL B 2 211 ? 33.610  33.622  -76.161 1.00 40.50  ? 205 VAL L N   1 
ATOM   3263 C CA  . VAL B 2 211 ? 34.869  34.171  -75.671 1.00 34.53  ? 205 VAL L CA  1 
ATOM   3264 C C   . VAL B 2 211 ? 35.834  33.030  -75.385 1.00 44.45  ? 205 VAL L C   1 
ATOM   3265 O O   . VAL B 2 211 ? 35.440  31.973  -74.877 1.00 53.18  ? 205 VAL L O   1 
ATOM   3266 C CB  . VAL B 2 211 ? 34.627  35.031  -74.417 1.00 32.66  ? 205 VAL L CB  1 
ATOM   3267 C CG1 . VAL B 2 211 ? 35.938  35.587  -73.877 1.00 39.43  ? 205 VAL L CG1 1 
ATOM   3268 C CG2 . VAL B 2 211 ? 33.655  36.158  -74.726 1.00 51.47  ? 205 VAL L CG2 1 
ATOM   3269 N N   . THR B 2 212 ? 37.108  33.236  -75.716 1.00 45.44  ? 206 THR L N   1 
ATOM   3270 C CA  . THR B 2 212 ? 38.146  32.243  -75.481 1.00 39.98  ? 206 THR L CA  1 
ATOM   3271 C C   . THR B 2 212 ? 39.277  32.863  -74.675 1.00 41.93  ? 206 THR L C   1 
ATOM   3272 O O   . THR B 2 212 ? 39.827  33.898  -75.063 1.00 58.88  ? 206 THR L O   1 
ATOM   3273 C CB  . THR B 2 212 ? 38.687  31.680  -76.801 1.00 34.13  ? 206 THR L CB  1 
ATOM   3274 O OG1 . THR B 2 212 ? 37.639  30.988  -77.491 1.00 38.29  ? 206 THR L OG1 1 
ATOM   3275 C CG2 . THR B 2 212 ? 39.837  30.717  -76.538 1.00 42.10  ? 206 THR L CG2 1 
ATOM   3276 N N   . LYS B 2 213 ? 39.614  32.230  -73.555 1.00 47.43  ? 207 LYS L N   1 
ATOM   3277 C CA  . LYS B 2 213 ? 40.788  32.571  -72.761 1.00 46.88  ? 207 LYS L CA  1 
ATOM   3278 C C   . LYS B 2 213 ? 41.806  31.452  -72.927 1.00 49.20  ? 207 LYS L C   1 
ATOM   3279 O O   . LYS B 2 213 ? 41.498  30.285  -72.663 1.00 43.34  ? 207 LYS L O   1 
ATOM   3280 C CB  . LYS B 2 213 ? 40.427  32.759  -71.287 1.00 49.03  ? 207 LYS L CB  1 
ATOM   3281 C CG  . LYS B 2 213 ? 40.006  34.172  -70.910 1.00 47.90  ? 207 LYS L CG  1 
ATOM   3282 C CD  . LYS B 2 213 ? 41.195  35.122  -70.907 1.00 61.22  ? 207 LYS L CD  1 
ATOM   3283 C CE  . LYS B 2 213 ? 40.825  36.478  -70.321 1.00 63.98  ? 207 LYS L CE  1 
ATOM   3284 N NZ  . LYS B 2 213 ? 39.796  37.183  -71.135 1.00 48.50  ? 207 LYS L NZ  1 
ATOM   3285 N N   . SER B 2 214 ? 43.010  31.805  -73.369 1.00 59.08  ? 208 SER L N   1 
ATOM   3286 C CA  . SER B 2 214 ? 44.037  30.815  -73.652 1.00 54.39  ? 208 SER L CA  1 
ATOM   3287 C C   . SER B 2 214 ? 45.391  31.334  -73.193 1.00 51.67  ? 208 SER L C   1 
ATOM   3288 O O   . SER B 2 214 ? 45.613  32.541  -73.074 1.00 66.47  ? 208 SER L O   1 
ATOM   3289 C CB  . SER B 2 214 ? 44.087  30.464  -75.145 1.00 52.32  ? 208 SER L CB  1 
ATOM   3290 O OG  . SER B 2 214 ? 44.400  31.605  -75.925 1.00 60.97  ? 208 SER L OG  1 
ATOM   3291 N N   . PHE B 2 215 ? 46.296  30.395  -72.931 1.00 51.33  ? 209 PHE L N   1 
ATOM   3292 C CA  . PHE B 2 215 ? 47.674  30.710  -72.590 1.00 51.52  ? 209 PHE L CA  1 
ATOM   3293 C C   . PHE B 2 215 ? 48.590  29.694  -73.252 1.00 53.55  ? 209 PHE L C   1 
ATOM   3294 O O   . PHE B 2 215 ? 48.206  28.543  -73.480 1.00 60.53  ? 209 PHE L O   1 
ATOM   3295 C CB  . PHE B 2 215 ? 47.905  30.716  -71.071 1.00 35.76  ? 209 PHE L CB  1 
ATOM   3296 C CG  . PHE B 2 215 ? 47.839  29.353  -70.438 1.00 43.37  ? 209 PHE L CG  1 
ATOM   3297 C CD1 . PHE B 2 215 ? 46.627  28.821  -70.034 1.00 47.15  ? 209 PHE L CD1 1 
ATOM   3298 C CD2 . PHE B 2 215 ? 48.992  28.606  -70.240 1.00 37.31  ? 209 PHE L CD2 1 
ATOM   3299 C CE1 . PHE B 2 215 ? 46.563  27.570  -69.451 1.00 50.24  ? 209 PHE L CE1 1 
ATOM   3300 C CE2 . PHE B 2 215 ? 48.933  27.354  -69.661 1.00 41.59  ? 209 PHE L CE2 1 
ATOM   3301 C CZ  . PHE B 2 215 ? 47.717  26.836  -69.265 1.00 50.38  ? 209 PHE L CZ  1 
ATOM   3302 N N   . ASN B 2 216 ? 49.807  30.129  -73.554 1.00 54.53  ? 210 ASN L N   1 
ATOM   3303 C CA  . ASN B 2 216 ? 50.837  29.260  -74.104 1.00 53.28  ? 210 ASN L CA  1 
ATOM   3304 C C   . ASN B 2 216 ? 51.783  28.853  -72.984 1.00 68.93  ? 210 ASN L C   1 
ATOM   3305 O O   . ASN B 2 216 ? 52.272  29.710  -72.240 1.00 86.19  ? 210 ASN L O   1 
ATOM   3306 C CB  . ASN B 2 216 ? 51.599  29.962  -75.228 1.00 51.92  ? 210 ASN L CB  1 
ATOM   3307 C CG  . ASN B 2 216 ? 50.679  30.482  -76.315 1.00 66.95  ? 210 ASN L CG  1 
ATOM   3308 O OD1 . ASN B 2 216 ? 49.455  30.457  -76.173 1.00 75.17  ? 210 ASN L OD1 1 
ATOM   3309 N ND2 . ASN B 2 216 ? 51.264  30.964  -77.404 1.00 73.85  ? 210 ASN L ND2 1 
ATOM   3310 N N   . ARG B 2 217 ? 52.028  27.550  -72.862 1.00 63.10  ? 211 ARG L N   1 
ATOM   3311 C CA  . ARG B 2 217 ? 52.827  27.024  -71.761 1.00 61.61  ? 211 ARG L CA  1 
ATOM   3312 C C   . ARG B 2 217 ? 54.222  27.635  -71.766 1.00 85.40  ? 211 ARG L C   1 
ATOM   3313 O O   . ARG B 2 217 ? 55.003  27.419  -72.698 1.00 80.99  ? 211 ARG L O   1 
ATOM   3314 C CB  . ARG B 2 217 ? 52.907  25.503  -71.860 1.00 56.45  ? 211 ARG L CB  1 
ATOM   3315 C CG  . ARG B 2 217 ? 53.881  24.865  -70.887 1.00 62.84  ? 211 ARG L CG  1 
ATOM   3316 C CD  . ARG B 2 217 ? 53.881  23.354  -71.033 1.00 56.34  ? 211 ARG L CD  1 
ATOM   3317 N NE  . ARG B 2 217 ? 54.062  22.943  -72.421 1.00 60.16  ? 211 ARG L NE  1 
ATOM   3318 C CZ  . ARG B 2 217 ? 55.240  22.750  -72.998 1.00 69.28  ? 211 ARG L CZ  1 
ATOM   3319 N NH1 . ARG B 2 217 ? 56.371  22.922  -72.334 1.00 68.91  ? 211 ARG L NH1 1 
ATOM   3320 N NH2 . ARG B 2 217 ? 55.283  22.374  -74.273 1.00 65.46  ? 211 ARG L NH2 1 
ATOM   3321 N N   . GLY B 2 218 ? 54.530  28.400  -70.723 1.00 84.12  ? 212 GLY L N   1 
ATOM   3322 C CA  . GLY B 2 218 ? 55.815  29.064  -70.617 1.00 75.83  ? 212 GLY L CA  1 
ATOM   3323 C C   . GLY B 2 218 ? 55.891  30.330  -71.446 1.00 65.57  ? 212 GLY L C   1 
ATOM   3324 O O   . GLY B 2 218 ? 56.136  30.280  -72.652 1.00 63.52  ? 212 GLY L O   1 
ATOM   3325 N N   . GLN C 3 1   ? -23.610 -33.966 -24.180 1.00 66.65  ? 1   GLN C N   1 
ATOM   3326 C CA  . GLN C 3 1   ? -22.672 -34.979 -24.649 1.00 62.60  ? 1   GLN C CA  1 
ATOM   3327 C C   . GLN C 3 1   ? -21.800 -34.407 -25.761 1.00 51.47  ? 1   GLN C C   1 
ATOM   3328 O O   . GLN C 3 1   ? -22.180 -34.424 -26.932 1.00 47.30  ? 1   GLN C O   1 
ATOM   3329 C CB  . GLN C 3 1   ? -23.421 -36.222 -25.139 1.00 62.92  ? 1   GLN C CB  1 
ATOM   3330 C CG  . GLN C 3 1   ? -24.719 -36.505 -24.391 1.00 76.02  ? 1   GLN C CG  1 
ATOM   3331 C CD  . GLN C 3 1   ? -24.519 -36.685 -22.896 1.00 98.64  ? 1   GLN C CD  1 
ATOM   3332 O OE1 . GLN C 3 1   ? -23.474 -37.157 -22.447 1.00 103.55 ? 1   GLN C OE1 1 
ATOM   3333 N NE2 . GLN C 3 1   ? -25.526 -36.306 -22.116 1.00 99.83  ? 1   GLN C NE2 1 
ATOM   3334 N N   . VAL C 3 2   ? -20.629 -33.903 -25.389 1.00 47.16  ? 2   VAL C N   1 
ATOM   3335 C CA  . VAL C 3 2   ? -19.763 -33.183 -26.313 1.00 45.57  ? 2   VAL C CA  1 
ATOM   3336 C C   . VAL C 3 2   ? -18.749 -34.151 -26.906 1.00 36.44  ? 2   VAL C C   1 
ATOM   3337 O O   . VAL C 3 2   ? -18.043 -34.854 -26.175 1.00 41.86  ? 2   VAL C O   1 
ATOM   3338 C CB  . VAL C 3 2   ? -19.059 -32.015 -25.607 1.00 36.30  ? 2   VAL C CB  1 
ATOM   3339 C CG1 . VAL C 3 2   ? -18.260 -31.197 -26.606 1.00 28.69  ? 2   VAL C CG1 1 
ATOM   3340 C CG2 . VAL C 3 2   ? -20.077 -31.148 -24.884 1.00 41.51  ? 2   VAL C CG2 1 
ATOM   3341 N N   . GLN C 3 3   ? -18.679 -34.191 -28.237 1.00 39.85  ? 3   GLN C N   1 
ATOM   3342 C CA  . GLN C 3 3   ? -17.719 -35.016 -28.957 1.00 40.85  ? 3   GLN C CA  1 
ATOM   3343 C C   . GLN C 3 3   ? -16.880 -34.138 -29.871 1.00 36.50  ? 3   GLN C C   1 
ATOM   3344 O O   . GLN C 3 3   ? -17.414 -33.266 -30.565 1.00 40.87  ? 3   GLN C O   1 
ATOM   3345 C CB  . GLN C 3 3   ? -18.418 -36.100 -29.783 1.00 46.01  ? 3   GLN C CB  1 
ATOM   3346 C CG  . GLN C 3 3   ? -19.233 -37.092 -28.976 1.00 48.08  ? 3   GLN C CG  1 
ATOM   3347 C CD  . GLN C 3 3   ? -19.692 -38.270 -29.813 1.00 47.29  ? 3   GLN C CD  1 
ATOM   3348 O OE1 . GLN C 3 3   ? -18.966 -38.743 -30.688 1.00 40.93  ? 3   GLN C OE1 1 
ATOM   3349 N NE2 . GLN C 3 3   ? -20.905 -38.745 -29.554 1.00 52.45  ? 3   GLN C NE2 1 
ATOM   3350 N N   . LEU C 3 4   ? -15.568 -34.367 -29.865 1.00 30.56  ? 4   LEU C N   1 
ATOM   3351 C CA  . LEU C 3 4   ? -14.645 -33.739 -30.806 1.00 28.61  ? 4   LEU C CA  1 
ATOM   3352 C C   . LEU C 3 4   ? -13.814 -34.848 -31.436 1.00 35.41  ? 4   LEU C C   1 
ATOM   3353 O O   . LEU C 3 4   ? -12.995 -35.476 -30.757 1.00 42.58  ? 4   LEU C O   1 
ATOM   3354 C CB  . LEU C 3 4   ? -13.753 -32.703 -30.119 1.00 19.75  ? 4   LEU C CB  1 
ATOM   3355 C CG  . LEU C 3 4   ? -14.306 -31.287 -29.932 1.00 23.33  ? 4   LEU C CG  1 
ATOM   3356 C CD1 . LEU C 3 4   ? -15.370 -31.237 -28.850 1.00 35.69  ? 4   LEU C CD1 1 
ATOM   3357 C CD2 . LEU C 3 4   ? -13.182 -30.310 -29.619 1.00 39.35  ? 4   LEU C CD2 1 
ATOM   3358 N N   . VAL C 3 5   ? -14.030 -35.095 -32.724 1.00 28.96  ? 5   VAL C N   1 
ATOM   3359 C CA  . VAL C 3 5   ? -13.363 -36.170 -33.448 1.00 36.31  ? 5   VAL C CA  1 
ATOM   3360 C C   . VAL C 3 5   ? -12.550 -35.551 -34.576 1.00 32.19  ? 5   VAL C C   1 
ATOM   3361 O O   . VAL C 3 5   ? -13.075 -34.755 -35.362 1.00 38.32  ? 5   VAL C O   1 
ATOM   3362 C CB  . VAL C 3 5   ? -14.370 -37.197 -33.995 1.00 34.88  ? 5   VAL C CB  1 
ATOM   3363 C CG1 . VAL C 3 5   ? -13.645 -38.423 -34.523 1.00 34.56  ? 5   VAL C CG1 1 
ATOM   3364 C CG2 . VAL C 3 5   ? -15.367 -37.581 -32.914 1.00 27.09  ? 5   VAL C CG2 1 
ATOM   3365 N N   . GLU C 3 6   ? -11.276 -35.919 -34.653 1.00 38.17  ? 6   GLU C N   1 
ATOM   3366 C CA  . GLU C 3 6   ? -10.344 -35.339 -35.605 1.00 38.50  ? 6   GLU C CA  1 
ATOM   3367 C C   . GLU C 3 6   ? -9.939  -36.362 -36.656 1.00 36.53  ? 6   GLU C C   1 
ATOM   3368 O O   . GLU C 3 6   ? -10.124 -37.571 -36.488 1.00 47.00  ? 6   GLU C O   1 
ATOM   3369 C CB  . GLU C 3 6   ? -9.099  -34.807 -34.890 1.00 32.33  ? 6   GLU C CB  1 
ATOM   3370 C CG  . GLU C 3 6   ? -9.415  -33.825 -33.785 1.00 44.41  ? 6   GLU C CG  1 
ATOM   3371 C CD  . GLU C 3 6   ? -8.305  -33.730 -32.763 1.00 52.47  ? 6   GLU C CD  1 
ATOM   3372 O OE1 . GLU C 3 6   ? -7.268  -33.102 -33.060 1.00 55.62  ? 6   GLU C OE1 1 
ATOM   3373 O OE2 . GLU C 3 6   ? -8.468  -34.298 -31.665 1.00 53.93  ? 6   GLU C OE2 1 
ATOM   3374 N N   . SER C 3 7   ? -9.379  -35.854 -37.749 1.00 27.49  ? 7   SER C N   1 
ATOM   3375 C CA  . SER C 3 7   ? -8.935  -36.685 -38.859 1.00 35.56  ? 7   SER C CA  1 
ATOM   3376 C C   . SER C 3 7   ? -7.991  -35.859 -39.722 1.00 29.19  ? 7   SER C C   1 
ATOM   3377 O O   . SER C 3 7   ? -7.678  -34.707 -39.409 1.00 28.15  ? 7   SER C O   1 
ATOM   3378 C CB  . SER C 3 7   ? -10.122 -37.205 -39.673 1.00 38.46  ? 7   SER C CB  1 
ATOM   3379 O OG  . SER C 3 7   ? -10.841 -36.130 -40.251 1.00 40.49  ? 7   SER C OG  1 
ATOM   3380 N N   . GLY C 3 8   ? -7.537  -36.462 -40.819 1.00 30.12  ? 8   GLY C N   1 
ATOM   3381 C CA  . GLY C 3 8   ? -6.675  -35.793 -41.765 1.00 44.20  ? 8   GLY C CA  1 
ATOM   3382 C C   . GLY C 3 8   ? -5.198  -35.863 -41.448 1.00 44.21  ? 8   GLY C C   1 
ATOM   3383 O O   . GLY C 3 8   ? -4.382  -35.447 -42.281 1.00 51.12  ? 8   GLY C O   1 
ATOM   3384 N N   . GLY C 3 9   ? -4.826  -36.369 -40.276 1.00 38.31  ? 9   GLY C N   1 
ATOM   3385 C CA  . GLY C 3 9   ? -3.423  -36.508 -39.952 1.00 33.81  ? 9   GLY C CA  1 
ATOM   3386 C C   . GLY C 3 9   ? -2.765  -37.612 -40.756 1.00 43.43  ? 9   GLY C C   1 
ATOM   3387 O O   . GLY C 3 9   ? -3.409  -38.553 -41.221 1.00 60.97  ? 9   GLY C O   1 
ATOM   3388 N N   . GLY C 3 10  ? -1.453  -37.490 -40.920 1.00 39.04  ? 10  GLY C N   1 
ATOM   3389 C CA  . GLY C 3 10  ? -0.713  -38.477 -41.680 1.00 44.97  ? 10  GLY C CA  1 
ATOM   3390 C C   . GLY C 3 10  ? 0.696   -37.995 -41.960 1.00 51.43  ? 10  GLY C C   1 
ATOM   3391 O O   . GLY C 3 10  ? 1.221   -37.128 -41.258 1.00 52.88  ? 10  GLY C O   1 
ATOM   3392 N N   . LEU C 3 11  ? 1.293   -38.572 -42.997 1.00 47.61  ? 11  LEU C N   1 
ATOM   3393 C CA  . LEU C 3 11  ? 2.657   -38.258 -43.397 1.00 43.25  ? 11  LEU C CA  1 
ATOM   3394 C C   . LEU C 3 11  ? 2.639   -37.348 -44.617 1.00 41.94  ? 11  LEU C C   1 
ATOM   3395 O O   . LEU C 3 11  ? 1.910   -37.605 -45.581 1.00 52.81  ? 11  LEU C O   1 
ATOM   3396 C CB  . LEU C 3 11  ? 3.444   -39.535 -43.695 1.00 38.66  ? 11  LEU C CB  1 
ATOM   3397 C CG  . LEU C 3 11  ? 4.838   -39.407 -44.317 1.00 43.93  ? 11  LEU C CG  1 
ATOM   3398 C CD1 . LEU C 3 11  ? 5.718   -38.429 -43.551 1.00 53.91  ? 11  LEU C CD1 1 
ATOM   3399 C CD2 . LEU C 3 11  ? 5.492   -40.774 -44.370 1.00 40.35  ? 11  LEU C CD2 1 
ATOM   3400 N N   . ILE C 3 12  ? 3.439   -36.286 -44.568 1.00 31.51  ? 12  ILE C N   1 
ATOM   3401 C CA  . ILE C 3 12  ? 3.559   -35.331 -45.662 1.00 40.92  ? 12  ILE C CA  1 
ATOM   3402 C C   . ILE C 3 12  ? 5.005   -34.857 -45.717 1.00 49.14  ? 12  ILE C C   1 
ATOM   3403 O O   . ILE C 3 12  ? 5.668   -34.735 -44.681 1.00 56.91  ? 12  ILE C O   1 
ATOM   3404 C CB  . ILE C 3 12  ? 2.581   -34.147 -45.488 1.00 56.22  ? 12  ILE C CB  1 
ATOM   3405 C CG1 . ILE C 3 12  ? 2.635   -33.210 -46.698 1.00 55.55  ? 12  ILE C CG1 1 
ATOM   3406 C CG2 . ILE C 3 12  ? 2.872   -33.395 -44.201 1.00 45.90  ? 12  ILE C CG2 1 
ATOM   3407 C CD1 . ILE C 3 12  ? 2.237   -33.874 -47.996 1.00 58.22  ? 12  ILE C CD1 1 
ATOM   3408 N N   . GLN C 3 13  ? 5.501   -34.611 -46.927 1.00 50.19  ? 13  GLN C N   1 
ATOM   3409 C CA  . GLN C 3 13  ? 6.875   -34.174 -47.099 1.00 51.46  ? 13  GLN C CA  1 
ATOM   3410 C C   . GLN C 3 13  ? 7.043   -32.732 -46.624 1.00 57.78  ? 13  GLN C C   1 
ATOM   3411 O O   . GLN C 3 13  ? 6.077   -31.967 -46.579 1.00 49.51  ? 13  GLN C O   1 
ATOM   3412 C CB  . GLN C 3 13  ? 7.291   -34.289 -48.563 1.00 60.23  ? 13  GLN C CB  1 
ATOM   3413 C CG  . GLN C 3 13  ? 6.623   -33.275 -49.473 1.00 71.20  ? 13  GLN C CG  1 
ATOM   3414 C CD  . GLN C 3 13  ? 7.499   -32.883 -50.645 1.00 92.32  ? 13  GLN C CD  1 
ATOM   3415 O OE1 . GLN C 3 13  ? 8.501   -33.538 -50.931 1.00 98.25  ? 13  GLN C OE1 1 
ATOM   3416 N NE2 . GLN C 3 13  ? 7.130   -31.801 -51.324 1.00 72.36  ? 13  GLN C NE2 1 
ATOM   3417 N N   . PRO C 3 14  ? 8.263   -32.344 -46.246 1.00 58.44  ? 14  PRO C N   1 
ATOM   3418 C CA  . PRO C 3 14  ? 8.505   -30.946 -45.869 1.00 43.34  ? 14  PRO C CA  1 
ATOM   3419 C C   . PRO C 3 14  ? 8.182   -29.999 -47.014 1.00 43.65  ? 14  PRO C C   1 
ATOM   3420 O O   . PRO C 3 14  ? 8.455   -30.286 -48.181 1.00 52.70  ? 14  PRO C O   1 
ATOM   3421 C CB  . PRO C 3 14  ? 9.997   -30.925 -45.523 1.00 26.37  ? 14  PRO C CB  1 
ATOM   3422 C CG  . PRO C 3 14  ? 10.306  -32.330 -45.131 1.00 40.63  ? 14  PRO C CG  1 
ATOM   3423 C CD  . PRO C 3 14  ? 9.449   -33.187 -46.016 1.00 47.99  ? 14  PRO C CD  1 
ATOM   3424 N N   . GLY C 3 15  ? 7.591   -28.858 -46.666 1.00 44.39  ? 15  GLY C N   1 
ATOM   3425 C CA  . GLY C 3 15  ? 7.117   -27.908 -47.647 1.00 36.88  ? 15  GLY C CA  1 
ATOM   3426 C C   . GLY C 3 15  ? 5.770   -28.238 -48.249 1.00 49.44  ? 15  GLY C C   1 
ATOM   3427 O O   . GLY C 3 15  ? 5.253   -27.440 -49.042 1.00 40.25  ? 15  GLY C O   1 
ATOM   3428 N N   . GLY C 3 16  ? 5.181   -29.375 -47.889 1.00 62.11  ? 16  GLY C N   1 
ATOM   3429 C CA  . GLY C 3 16  ? 3.910   -29.793 -48.437 1.00 52.63  ? 16  GLY C CA  1 
ATOM   3430 C C   . GLY C 3 16  ? 2.739   -29.156 -47.715 1.00 54.08  ? 16  GLY C C   1 
ATOM   3431 O O   . GLY C 3 16  ? 2.882   -28.230 -46.915 1.00 49.50  ? 16  GLY C O   1 
ATOM   3432 N N   . SER C 3 17  ? 1.551   -29.675 -48.013 1.00 49.76  ? 17  SER C N   1 
ATOM   3433 C CA  . SER C 3 17  ? 0.313   -29.149 -47.460 1.00 45.89  ? 17  SER C CA  1 
ATOM   3434 C C   . SER C 3 17  ? -0.509  -30.270 -46.844 1.00 42.54  ? 17  SER C C   1 
ATOM   3435 O O   . SER C 3 17  ? -0.570  -31.380 -47.382 1.00 45.79  ? 17  SER C O   1 
ATOM   3436 C CB  . SER C 3 17  ? -0.512  -28.424 -48.529 1.00 43.43  ? 17  SER C CB  1 
ATOM   3437 O OG  . SER C 3 17  ? 0.135   -27.235 -48.948 1.00 44.97  ? 17  SER C OG  1 
ATOM   3438 N N   . LEU C 3 18  ? -1.136  -29.968 -45.709 1.00 52.44  ? 18  LEU C N   1 
ATOM   3439 C CA  . LEU C 3 18  ? -2.034  -30.883 -45.022 1.00 35.47  ? 18  LEU C CA  1 
ATOM   3440 C C   . LEU C 3 18  ? -3.153  -30.069 -44.391 1.00 39.70  ? 18  LEU C C   1 
ATOM   3441 O O   . LEU C 3 18  ? -2.974  -28.891 -44.070 1.00 40.76  ? 18  LEU C O   1 
ATOM   3442 C CB  . LEU C 3 18  ? -1.301  -31.698 -43.946 1.00 20.93  ? 18  LEU C CB  1 
ATOM   3443 C CG  . LEU C 3 18  ? -1.948  -33.016 -43.517 1.00 32.35  ? 18  LEU C CG  1 
ATOM   3444 C CD1 . LEU C 3 18  ? -1.496  -34.153 -44.420 1.00 47.29  ? 18  LEU C CD1 1 
ATOM   3445 C CD2 . LEU C 3 18  ? -1.640  -33.331 -42.065 1.00 43.88  ? 18  LEU C CD2 1 
ATOM   3446 N N   . ARG C 3 19  ? -4.314  -30.698 -44.217 1.00 33.98  ? 19  ARG C N   1 
ATOM   3447 C CA  . ARG C 3 19  ? -5.467  -30.017 -43.634 1.00 28.57  ? 19  ARG C CA  1 
ATOM   3448 C C   . ARG C 3 19  ? -6.191  -30.979 -42.704 1.00 26.77  ? 19  ARG C C   1 
ATOM   3449 O O   . ARG C 3 19  ? -6.760  -31.976 -43.157 1.00 44.33  ? 19  ARG C O   1 
ATOM   3450 C CB  . ARG C 3 19  ? -6.416  -29.496 -44.712 1.00 31.23  ? 19  ARG C CB  1 
ATOM   3451 C CG  . ARG C 3 19  ? -7.417  -28.475 -44.191 1.00 43.79  ? 19  ARG C CG  1 
ATOM   3452 C CD  . ARG C 3 19  ? -8.660  -28.429 -45.057 1.00 45.55  ? 19  ARG C CD  1 
ATOM   3453 N NE  . ARG C 3 19  ? -9.358  -29.708 -45.054 1.00 50.67  ? 19  ARG C NE  1 
ATOM   3454 C CZ  . ARG C 3 19  ? -10.470 -29.955 -45.730 1.00 49.41  ? 19  ARG C CZ  1 
ATOM   3455 N NH1 . ARG C 3 19  ? -11.045 -29.027 -46.478 1.00 34.07  ? 19  ARG C NH1 1 
ATOM   3456 N NH2 . ARG C 3 19  ? -11.019 -31.165 -45.657 1.00 64.17  ? 19  ARG C NH2 1 
ATOM   3457 N N   . LEU C 3 20  ? -6.179  -30.669 -41.413 1.00 30.85  ? 20  LEU C N   1 
ATOM   3458 C CA  . LEU C 3 20  ? -6.879  -31.463 -40.418 1.00 31.42  ? 20  LEU C CA  1 
ATOM   3459 C C   . LEU C 3 20  ? -8.327  -31.007 -40.299 1.00 34.48  ? 20  LEU C C   1 
ATOM   3460 O O   . LEU C 3 20  ? -8.655  -29.840 -40.527 1.00 44.05  ? 20  LEU C O   1 
ATOM   3461 C CB  . LEU C 3 20  ? -6.187  -31.355 -39.061 1.00 31.71  ? 20  LEU C CB  1 
ATOM   3462 C CG  . LEU C 3 20  ? -4.683  -31.618 -39.080 1.00 36.87  ? 20  LEU C CG  1 
ATOM   3463 C CD1 . LEU C 3 20  ? -4.102  -31.472 -37.689 1.00 33.42  ? 20  LEU C CD1 1 
ATOM   3464 C CD2 . LEU C 3 20  ? -4.386  -32.997 -39.645 1.00 37.84  ? 20  LEU C CD2 1 
ATOM   3465 N N   . SER C 3 21  ? -9.193  -31.948 -39.938 1.00 24.26  ? 21  SER C N   1 
ATOM   3466 C CA  . SER C 3 21  ? -10.604 -31.682 -39.718 1.00 29.19  ? 21  SER C CA  1 
ATOM   3467 C C   . SER C 3 21  ? -10.968 -32.054 -38.288 1.00 35.22  ? 21  SER C C   1 
ATOM   3468 O O   . SER C 3 21  ? -10.323 -32.906 -37.670 1.00 36.99  ? 21  SER C O   1 
ATOM   3469 C CB  . SER C 3 21  ? -11.480 -32.462 -40.705 1.00 33.13  ? 21  SER C CB  1 
ATOM   3470 O OG  . SER C 3 21  ? -11.182 -32.104 -42.042 1.00 43.88  ? 21  SER C OG  1 
ATOM   3471 N N   . CYS C 3 22  ? -12.004 -31.400 -37.763 1.00 31.96  ? 22  CYS C N   1 
ATOM   3472 C CA  . CYS C 3 22  ? -12.433 -31.636 -36.386 1.00 26.02  ? 22  CYS C CA  1 
ATOM   3473 C C   . CYS C 3 22  ? -13.951 -31.493 -36.331 1.00 33.87  ? 22  CYS C C   1 
ATOM   3474 O O   . CYS C 3 22  ? -14.466 -30.381 -36.186 1.00 38.97  ? 22  CYS C O   1 
ATOM   3475 C CB  . CYS C 3 22  ? -11.749 -30.672 -35.429 1.00 35.93  ? 22  CYS C CB  1 
ATOM   3476 S SG  . CYS C 3 22  ? -12.422 -30.698 -33.754 1.00 72.42  ? 22  CYS C SG  1 
ATOM   3477 N N   . ALA C 3 23  ? -14.654 -32.617 -36.443 1.00 39.26  ? 23  ALA C N   1 
ATOM   3478 C CA  . ALA C 3 23  ? -16.100 -32.612 -36.279 1.00 31.00  ? 23  ALA C CA  1 
ATOM   3479 C C   . ALA C 3 23  ? -16.459 -32.413 -34.812 1.00 28.92  ? 23  ALA C C   1 
ATOM   3480 O O   . ALA C 3 23  ? -15.817 -32.971 -33.917 1.00 32.13  ? 23  ALA C O   1 
ATOM   3481 C CB  . ALA C 3 23  ? -16.701 -33.916 -36.800 1.00 36.06  ? 23  ALA C CB  1 
ATOM   3482 N N   . ALA C 3 24  ? -17.492 -31.611 -34.565 1.00 28.66  ? 24  ALA C N   1 
ATOM   3483 C CA  . ALA C 3 24  ? -17.902 -31.267 -33.212 1.00 28.03  ? 24  ALA C CA  1 
ATOM   3484 C C   . ALA C 3 24  ? -19.390 -31.522 -33.035 1.00 31.09  ? 24  ALA C C   1 
ATOM   3485 O O   . ALA C 3 24  ? -20.193 -31.225 -33.925 1.00 36.84  ? 24  ALA C O   1 
ATOM   3486 C CB  . ALA C 3 24  ? -17.582 -29.803 -32.888 1.00 38.64  ? 24  ALA C CB  1 
ATOM   3487 N N   . SER C 3 25  ? -19.748 -32.073 -31.878 1.00 36.53  ? 25  SER C N   1 
ATOM   3488 C CA  . SER C 3 25  ? -21.132 -32.327 -31.512 1.00 37.83  ? 25  SER C CA  1 
ATOM   3489 C C   . SER C 3 25  ? -21.372 -31.843 -30.089 1.00 33.90  ? 25  SER C C   1 
ATOM   3490 O O   . SER C 3 25  ? -20.458 -31.823 -29.262 1.00 38.53  ? 25  SER C O   1 
ATOM   3491 C CB  . SER C 3 25  ? -21.480 -33.820 -31.624 1.00 40.15  ? 25  SER C CB  1 
ATOM   3492 O OG  . SER C 3 25  ? -22.792 -34.079 -31.153 1.00 62.73  ? 25  SER C OG  1 
ATOM   3493 N N   . GLY C 3 26  ? -22.616 -31.453 -29.811 1.00 28.57  ? 26  GLY C N   1 
ATOM   3494 C CA  . GLY C 3 26  ? -23.003 -31.005 -28.490 1.00 35.80  ? 26  GLY C CA  1 
ATOM   3495 C C   . GLY C 3 26  ? -22.920 -29.511 -28.255 1.00 41.36  ? 26  GLY C C   1 
ATOM   3496 O O   . GLY C 3 26  ? -23.327 -29.049 -27.181 1.00 39.45  ? 26  GLY C O   1 
ATOM   3497 N N   . PHE C 3 27  ? -22.405 -28.743 -29.212 1.00 39.42  ? 27  PHE C N   1 
ATOM   3498 C CA  . PHE C 3 27  ? -22.369 -27.292 -29.092 1.00 30.09  ? 27  PHE C CA  1 
ATOM   3499 C C   . PHE C 3 27  ? -22.238 -26.693 -30.484 1.00 34.03  ? 27  PHE C C   1 
ATOM   3500 O O   . PHE C 3 27  ? -21.815 -27.363 -31.430 1.00 32.45  ? 27  PHE C O   1 
ATOM   3501 C CB  . PHE C 3 27  ? -21.223 -26.823 -28.187 1.00 36.80  ? 27  PHE C CB  1 
ATOM   3502 C CG  . PHE C 3 27  ? -19.855 -27.082 -28.751 1.00 36.69  ? 27  PHE C CG  1 
ATOM   3503 C CD1 . PHE C 3 27  ? -19.269 -28.331 -28.636 1.00 37.41  ? 27  PHE C CD1 1 
ATOM   3504 C CD2 . PHE C 3 27  ? -19.150 -26.073 -29.387 1.00 40.02  ? 27  PHE C CD2 1 
ATOM   3505 C CE1 . PHE C 3 27  ? -18.008 -28.572 -29.152 1.00 34.44  ? 27  PHE C CE1 1 
ATOM   3506 C CE2 . PHE C 3 27  ? -17.891 -26.308 -29.905 1.00 36.62  ? 27  PHE C CE2 1 
ATOM   3507 C CZ  . PHE C 3 27  ? -17.319 -27.558 -29.787 1.00 30.00  ? 27  PHE C CZ  1 
ATOM   3508 N N   . THR C 3 28  ? -22.607 -25.418 -30.597 1.00 36.72  ? 28  THR C N   1 
ATOM   3509 C CA  . THR C 3 28  ? -22.543 -24.719 -31.872 1.00 27.37  ? 28  THR C CA  1 
ATOM   3510 C C   . THR C 3 28  ? -21.109 -24.273 -32.135 1.00 32.19  ? 28  THR C C   1 
ATOM   3511 O O   . THR C 3 28  ? -20.506 -23.577 -31.310 1.00 38.49  ? 28  THR C O   1 
ATOM   3512 C CB  . THR C 3 28  ? -23.494 -23.521 -31.874 1.00 33.16  ? 28  THR C CB  1 
ATOM   3513 O OG1 . THR C 3 28  ? -24.801 -23.946 -31.467 1.00 35.11  ? 28  THR C OG1 1 
ATOM   3514 C CG2 . THR C 3 28  ? -23.581 -22.914 -33.265 1.00 40.28  ? 28  THR C CG2 1 
ATOM   3515 N N   . VAL C 3 29  ? -20.565 -24.673 -33.285 1.00 30.86  ? 29  VAL C N   1 
ATOM   3516 C CA  . VAL C 3 29  ? -19.168 -24.380 -33.594 1.00 25.23  ? 29  VAL C CA  1 
ATOM   3517 C C   . VAL C 3 29  ? -18.959 -22.881 -33.779 1.00 33.77  ? 29  VAL C C   1 
ATOM   3518 O O   . VAL C 3 29  ? -18.016 -22.298 -33.231 1.00 43.55  ? 29  VAL C O   1 
ATOM   3519 C CB  . VAL C 3 29  ? -18.719 -25.171 -34.836 1.00 32.81  ? 29  VAL C CB  1 
ATOM   3520 C CG1 . VAL C 3 29  ? -17.324 -24.745 -35.266 1.00 34.76  ? 29  VAL C CG1 1 
ATOM   3521 C CG2 . VAL C 3 29  ? -18.759 -26.665 -34.556 1.00 35.03  ? 29  VAL C CG2 1 
ATOM   3522 N N   . SER C 3 30  ? -19.840 -22.233 -34.547 1.00 30.98  ? 30  SER C N   1 
ATOM   3523 C CA  . SER C 3 30  ? -19.661 -20.819 -34.858 1.00 37.78  ? 30  SER C CA  1 
ATOM   3524 C C   . SER C 3 30  ? -19.895 -19.915 -33.656 1.00 37.77  ? 30  SER C C   1 
ATOM   3525 O O   . SER C 3 30  ? -19.440 -18.766 -33.664 1.00 47.85  ? 30  SER C O   1 
ATOM   3526 C CB  . SER C 3 30  ? -20.597 -20.404 -35.994 1.00 45.74  ? 30  SER C CB  1 
ATOM   3527 O OG  . SER C 3 30  ? -21.954 -20.598 -35.634 1.00 38.72  ? 30  SER C OG  1 
ATOM   3528 N N   . SER C 3 31  ? -20.588 -20.399 -32.630 1.00 30.91  ? 31  SER C N   1 
ATOM   3529 C CA  . SER C 3 31  ? -20.880 -19.599 -31.449 1.00 37.33  ? 31  SER C CA  1 
ATOM   3530 C C   . SER C 3 31  ? -19.823 -19.735 -30.362 1.00 34.93  ? 31  SER C C   1 
ATOM   3531 O O   . SER C 3 31  ? -19.973 -19.130 -29.296 1.00 33.80  ? 31  SER C O   1 
ATOM   3532 C CB  . SER C 3 31  ? -22.251 -19.981 -30.879 1.00 36.03  ? 31  SER C CB  1 
ATOM   3533 O OG  . SER C 3 31  ? -23.280 -19.745 -31.824 1.00 46.97  ? 31  SER C OG  1 
ATOM   3534 N N   . ASN C 3 32  ? -18.760 -20.498 -30.605 1.00 33.67  ? 32  ASN C N   1 
ATOM   3535 C CA  . ASN C 3 32  ? -17.756 -20.779 -29.592 1.00 32.48  ? 32  ASN C CA  1 
ATOM   3536 C C   . ASN C 3 32  ? -16.366 -20.449 -30.114 1.00 37.76  ? 32  ASN C C   1 
ATOM   3537 O O   . ASN C 3 32  ? -16.113 -20.439 -31.322 1.00 40.07  ? 32  ASN C O   1 
ATOM   3538 C CB  . ASN C 3 32  ? -17.794 -22.250 -29.152 1.00 27.88  ? 32  ASN C CB  1 
ATOM   3539 C CG  . ASN C 3 32  ? -19.028 -22.587 -28.347 1.00 30.58  ? 32  ASN C CG  1 
ATOM   3540 O OD1 . ASN C 3 32  ? -18.981 -22.658 -27.118 1.00 35.78  ? 32  ASN C OD1 1 
ATOM   3541 N ND2 . ASN C 3 32  ? -20.144 -22.801 -29.034 1.00 36.32  ? 32  ASN C ND2 1 
ATOM   3542 N N   . TYR C 3 33  ? -15.466 -20.171 -29.175 1.00 33.80  ? 33  TYR C N   1 
ATOM   3543 C CA  . TYR C 3 33  ? -14.046 -20.120 -29.484 1.00 31.73  ? 33  TYR C CA  1 
ATOM   3544 C C   . TYR C 3 33  ? -13.529 -21.532 -29.733 1.00 28.09  ? 33  TYR C C   1 
ATOM   3545 O O   . TYR C 3 33  ? -13.848 -22.465 -28.991 1.00 32.48  ? 33  TYR C O   1 
ATOM   3546 C CB  . TYR C 3 33  ? -13.266 -19.478 -28.335 1.00 41.49  ? 33  TYR C CB  1 
ATOM   3547 C CG  . TYR C 3 33  ? -13.610 -18.033 -28.030 1.00 47.35  ? 33  TYR C CG  1 
ATOM   3548 C CD1 . TYR C 3 33  ? -14.837 -17.687 -27.475 1.00 45.65  ? 33  TYR C CD1 1 
ATOM   3549 C CD2 . TYR C 3 33  ? -12.691 -17.019 -28.262 1.00 46.18  ? 33  TYR C CD2 1 
ATOM   3550 C CE1 . TYR C 3 33  ? -15.146 -16.370 -27.187 1.00 49.98  ? 33  TYR C CE1 1 
ATOM   3551 C CE2 . TYR C 3 33  ? -12.990 -15.700 -27.975 1.00 43.06  ? 33  TYR C CE2 1 
ATOM   3552 C CZ  . TYR C 3 33  ? -14.218 -15.381 -27.438 1.00 47.43  ? 33  TYR C CZ  1 
ATOM   3553 O OH  . TYR C 3 33  ? -14.519 -14.070 -27.151 1.00 47.60  ? 33  TYR C OH  1 
ATOM   3554 N N   . MET C 3 34  ? -12.732 -21.691 -30.786 1.00 29.37  ? 34  MET C N   1 
ATOM   3555 C CA  . MET C 3 34  ? -12.144 -22.978 -31.132 1.00 30.09  ? 34  MET C CA  1 
ATOM   3556 C C   . MET C 3 34  ? -10.646 -22.805 -31.329 1.00 33.96  ? 34  MET C C   1 
ATOM   3557 O O   . MET C 3 34  ? -10.203 -21.828 -31.941 1.00 35.00  ? 34  MET C O   1 
ATOM   3558 C CB  . MET C 3 34  ? -12.783 -23.563 -32.398 1.00 31.84  ? 34  MET C CB  1 
ATOM   3559 C CG  . MET C 3 34  ? -14.283 -23.811 -32.288 1.00 32.97  ? 34  MET C CG  1 
ATOM   3560 S SD  . MET C 3 34  ? -14.711 -25.253 -31.291 1.00 42.49  ? 34  MET C SD  1 
ATOM   3561 C CE  . MET C 3 34  ? -14.496 -26.574 -32.482 1.00 33.44  ? 34  MET C CE  1 
ATOM   3562 N N   . SER C 3 35  ? -9.868  -23.755 -30.809 1.00 35.51  ? 35  SER C N   1 
ATOM   3563 C CA  . SER C 3 35  ? -8.415  -23.664 -30.851 1.00 37.98  ? 35  SER C CA  1 
ATOM   3564 C C   . SER C 3 35  ? -7.809  -24.999 -31.257 1.00 36.54  ? 35  SER C C   1 
ATOM   3565 O O   . SER C 3 35  ? -8.379  -26.064 -31.005 1.00 30.70  ? 35  SER C O   1 
ATOM   3566 C CB  . SER C 3 35  ? -7.831  -23.236 -29.498 1.00 32.73  ? 35  SER C CB  1 
ATOM   3567 O OG  . SER C 3 35  ? -8.185  -21.903 -29.180 1.00 37.64  ? 35  SER C OG  1 
ATOM   3568 N N   . TRP C 3 36  ? -6.640  -24.922 -31.886 1.00 35.44  ? 36  TRP C N   1 
ATOM   3569 C CA  . TRP C 3 36  ? -5.809  -26.082 -32.178 1.00 31.97  ? 36  TRP C CA  1 
ATOM   3570 C C   . TRP C 3 36  ? -4.594  -26.053 -31.261 1.00 32.37  ? 36  TRP C C   1 
ATOM   3571 O O   . TRP C 3 36  ? -3.915  -25.027 -31.159 1.00 37.80  ? 36  TRP C O   1 
ATOM   3572 C CB  . TRP C 3 36  ? -5.363  -26.095 -33.643 1.00 32.75  ? 36  TRP C CB  1 
ATOM   3573 C CG  . TRP C 3 36  ? -6.442  -26.451 -34.621 1.00 31.07  ? 36  TRP C CG  1 
ATOM   3574 C CD1 . TRP C 3 36  ? -7.250  -25.588 -35.302 1.00 32.28  ? 36  TRP C CD1 1 
ATOM   3575 C CD2 . TRP C 3 36  ? -6.822  -27.769 -35.037 1.00 38.63  ? 36  TRP C CD2 1 
ATOM   3576 N NE1 . TRP C 3 36  ? -8.113  -26.286 -36.113 1.00 33.86  ? 36  TRP C NE1 1 
ATOM   3577 C CE2 . TRP C 3 36  ? -7.872  -27.627 -35.967 1.00 35.47  ? 36  TRP C CE2 1 
ATOM   3578 C CE3 . TRP C 3 36  ? -6.381  -29.055 -34.710 1.00 35.79  ? 36  TRP C CE3 1 
ATOM   3579 C CZ2 . TRP C 3 36  ? -8.484  -28.721 -36.575 1.00 29.16  ? 36  TRP C CZ2 1 
ATOM   3580 C CZ3 . TRP C 3 36  ? -6.990  -30.140 -35.314 1.00 26.86  ? 36  TRP C CZ3 1 
ATOM   3581 C CH2 . TRP C 3 36  ? -8.030  -29.966 -36.236 1.00 28.69  ? 36  TRP C CH2 1 
ATOM   3582 N N   . VAL C 3 37  ? -4.331  -27.172 -30.589 1.00 31.84  ? 37  VAL C N   1 
ATOM   3583 C CA  . VAL C 3 37  ? -3.182  -27.315 -29.701 1.00 34.68  ? 37  VAL C CA  1 
ATOM   3584 C C   . VAL C 3 37  ? -2.417  -28.564 -30.112 1.00 40.93  ? 37  VAL C C   1 
ATOM   3585 O O   . VAL C 3 37  ? -3.016  -29.631 -30.287 1.00 36.75  ? 37  VAL C O   1 
ATOM   3586 C CB  . VAL C 3 37  ? -3.607  -27.404 -28.223 1.00 34.73  ? 37  VAL C CB  1 
ATOM   3587 C CG1 . VAL C 3 37  ? -2.389  -27.590 -27.329 1.00 34.08  ? 37  VAL C CG1 1 
ATOM   3588 C CG2 . VAL C 3 37  ? -4.388  -26.165 -27.816 1.00 34.64  ? 37  VAL C CG2 1 
ATOM   3589 N N   . ARG C 3 38  ? -1.102  -28.437 -30.266 1.00 37.17  ? 38  ARG C N   1 
ATOM   3590 C CA  . ARG C 3 38  ? -0.257  -29.552 -30.669 1.00 39.72  ? 38  ARG C CA  1 
ATOM   3591 C C   . ARG C 3 38  ? 0.720   -29.904 -29.556 1.00 41.05  ? 38  ARG C C   1 
ATOM   3592 O O   . ARG C 3 38  ? 1.226   -29.022 -28.854 1.00 39.37  ? 38  ARG C O   1 
ATOM   3593 C CB  . ARG C 3 38  ? 0.510   -29.233 -31.958 1.00 36.45  ? 38  ARG C CB  1 
ATOM   3594 C CG  . ARG C 3 38  ? 1.607   -28.190 -31.808 1.00 34.47  ? 38  ARG C CG  1 
ATOM   3595 C CD  . ARG C 3 38  ? 2.291   -27.910 -33.136 1.00 38.63  ? 38  ARG C CD  1 
ATOM   3596 N NE  . ARG C 3 38  ? 3.243   -26.810 -33.039 1.00 38.27  ? 38  ARG C NE  1 
ATOM   3597 C CZ  . ARG C 3 38  ? 3.865   -26.263 -34.075 1.00 38.77  ? 38  ARG C CZ  1 
ATOM   3598 N NH1 . ARG C 3 38  ? 3.657   -26.689 -35.310 1.00 40.99  ? 38  ARG C NH1 1 
ATOM   3599 N NH2 . ARG C 3 38  ? 4.715   -25.261 -33.866 1.00 37.94  ? 38  ARG C NH2 1 
ATOM   3600 N N   . GLN C 3 39  ? 0.960   -31.201 -29.382 1.00 57.43  ? 39  GLN C N   1 
ATOM   3601 C CA  . GLN C 3 39  ? 1.974   -31.704 -28.462 1.00 51.13  ? 39  GLN C CA  1 
ATOM   3602 C C   . GLN C 3 39  ? 3.006   -32.466 -29.282 1.00 52.61  ? 39  GLN C C   1 
ATOM   3603 O O   . GLN C 3 39  ? 2.715   -33.549 -29.802 1.00 59.09  ? 39  GLN C O   1 
ATOM   3604 C CB  . GLN C 3 39  ? 1.362   -32.597 -27.383 1.00 43.84  ? 39  GLN C CB  1 
ATOM   3605 C CG  . GLN C 3 39  ? 2.375   -33.103 -26.366 1.00 48.14  ? 39  GLN C CG  1 
ATOM   3606 C CD  . GLN C 3 39  ? 1.738   -33.905 -25.247 1.00 59.42  ? 39  GLN C CD  1 
ATOM   3607 O OE1 . GLN C 3 39  ? 2.220   -33.899 -24.113 1.00 54.13  ? 39  GLN C OE1 1 
ATOM   3608 N NE2 . GLN C 3 39  ? 0.655   -34.607 -25.561 1.00 56.30  ? 39  GLN C NE2 1 
ATOM   3609 N N   . ALA C 3 40  ? 4.201   -31.897 -29.402 1.00 60.56  ? 40  ALA C N   1 
ATOM   3610 C CA  . ALA C 3 40  ? 5.271   -32.570 -30.116 1.00 71.55  ? 40  ALA C CA  1 
ATOM   3611 C C   . ALA C 3 40  ? 5.651   -33.854 -29.378 1.00 84.65  ? 40  ALA C C   1 
ATOM   3612 O O   . ALA C 3 40  ? 5.546   -33.926 -28.150 1.00 80.43  ? 40  ALA C O   1 
ATOM   3613 C CB  . ALA C 3 40  ? 6.479   -31.647 -30.254 1.00 51.44  ? 40  ALA C CB  1 
ATOM   3614 N N   . PRO C 3 41  ? 6.085   -34.894 -30.106 1.00 101.10 ? 41  PRO C N   1 
ATOM   3615 C CA  . PRO C 3 41  ? 6.289   -36.204 -29.468 1.00 98.81  ? 41  PRO C CA  1 
ATOM   3616 C C   . PRO C 3 41  ? 7.361   -36.182 -28.391 1.00 94.71  ? 41  PRO C C   1 
ATOM   3617 O O   . PRO C 3 41  ? 8.550   -36.019 -28.682 1.00 87.04  ? 41  PRO C O   1 
ATOM   3618 C CB  . PRO C 3 41  ? 6.692   -37.107 -30.642 1.00 73.30  ? 41  PRO C CB  1 
ATOM   3619 C CG  . PRO C 3 41  ? 7.244   -36.172 -31.666 1.00 86.01  ? 41  PRO C CG  1 
ATOM   3620 C CD  . PRO C 3 41  ? 6.437   -34.916 -31.537 1.00 90.82  ? 41  PRO C CD  1 
ATOM   3621 N N   . GLY C 3 42  ? 6.944   -36.366 -27.140 1.00 88.93  ? 42  GLY C N   1 
ATOM   3622 C CA  . GLY C 3 42  ? 7.854   -36.299 -26.018 1.00 86.13  ? 42  GLY C CA  1 
ATOM   3623 C C   . GLY C 3 42  ? 8.121   -34.909 -25.488 1.00 91.53  ? 42  GLY C C   1 
ATOM   3624 O O   . GLY C 3 42  ? 9.003   -34.748 -24.637 1.00 97.81  ? 42  GLY C O   1 
ATOM   3625 N N   . LYS C 3 43  ? 7.395   -33.902 -25.961 1.00 94.21  ? 43  LYS C N   1 
ATOM   3626 C CA  . LYS C 3 43  ? 7.553   -32.527 -25.509 1.00 93.52  ? 43  LYS C CA  1 
ATOM   3627 C C   . LYS C 3 43  ? 6.228   -32.028 -24.928 1.00 86.26  ? 43  LYS C C   1 
ATOM   3628 O O   . LYS C 3 43  ? 5.257   -32.778 -24.803 1.00 76.06  ? 43  LYS C O   1 
ATOM   3629 C CB  . LYS C 3 43  ? 8.039   -31.629 -26.651 1.00 74.94  ? 43  LYS C CB  1 
ATOM   3630 C CG  . LYS C 3 43  ? 9.373   -32.035 -27.268 1.00 73.00  ? 43  LYS C CG  1 
ATOM   3631 C CD  . LYS C 3 43  ? 9.171   -32.959 -28.457 1.00 79.29  ? 43  LYS C CD  1 
ATOM   3632 C CE  . LYS C 3 43  ? 10.138  -32.646 -29.586 1.00 65.07  ? 43  LYS C CE  1 
ATOM   3633 N NZ  . LYS C 3 43  ? 9.645   -33.183 -30.886 1.00 40.30  ? 43  LYS C NZ  1 
ATOM   3634 N N   . GLY C 3 44  ? 6.198   -30.742 -24.574 1.00 83.96  ? 44  GLY C N   1 
ATOM   3635 C CA  . GLY C 3 44  ? 5.024   -30.164 -23.958 1.00 83.48  ? 44  GLY C CA  1 
ATOM   3636 C C   . GLY C 3 44  ? 3.982   -29.700 -24.960 1.00 70.36  ? 44  GLY C C   1 
ATOM   3637 O O   . GLY C 3 44  ? 4.186   -29.705 -26.173 1.00 74.95  ? 44  GLY C O   1 
ATOM   3638 N N   . LEU C 3 45  ? 2.837   -29.290 -24.421 1.00 54.17  ? 45  LEU C N   1 
ATOM   3639 C CA  . LEU C 3 45  ? 1.748   -28.765 -25.231 1.00 36.02  ? 45  LEU C CA  1 
ATOM   3640 C C   . LEU C 3 45  ? 2.061   -27.349 -25.700 1.00 33.41  ? 45  LEU C C   1 
ATOM   3641 O O   . LEU C 3 45  ? 2.731   -26.575 -25.010 1.00 42.39  ? 45  LEU C O   1 
ATOM   3642 C CB  . LEU C 3 45  ? 0.440   -28.776 -24.439 1.00 36.21  ? 45  LEU C CB  1 
ATOM   3643 C CG  . LEU C 3 45  ? -0.165  -30.143 -24.110 1.00 47.10  ? 45  LEU C CG  1 
ATOM   3644 C CD1 . LEU C 3 45  ? -1.091  -30.042 -22.910 1.00 38.75  ? 45  LEU C CD1 1 
ATOM   3645 C CD2 . LEU C 3 45  ? -0.914  -30.693 -25.312 1.00 46.03  ? 45  LEU C CD2 1 
ATOM   3646 N N   . GLU C 3 46  ? 1.568   -27.014 -26.892 1.00 30.83  ? 46  GLU C N   1 
ATOM   3647 C CA  . GLU C 3 46  ? 1.806   -25.709 -27.496 1.00 37.84  ? 46  GLU C CA  1 
ATOM   3648 C C   . GLU C 3 46  ? 0.547   -25.234 -28.207 1.00 43.25  ? 46  GLU C C   1 
ATOM   3649 O O   . GLU C 3 46  ? 0.007   -25.946 -29.059 1.00 35.04  ? 46  GLU C O   1 
ATOM   3650 C CB  . GLU C 3 46  ? 2.975   -25.764 -28.485 1.00 25.99  ? 46  GLU C CB  1 
ATOM   3651 C CG  . GLU C 3 46  ? 3.281   -24.435 -29.157 1.00 45.88  ? 46  GLU C CG  1 
ATOM   3652 C CD  . GLU C 3 46  ? 4.319   -24.563 -30.255 1.00 51.00  ? 46  GLU C CD  1 
ATOM   3653 O OE1 . GLU C 3 46  ? 4.644   -25.708 -30.635 1.00 54.98  ? 46  GLU C OE1 1 
ATOM   3654 O OE2 . GLU C 3 46  ? 4.808   -23.519 -30.738 1.00 32.18  ? 46  GLU C OE2 1 
ATOM   3655 N N   . TRP C 3 47  ? 0.088   -24.033 -27.860 1.00 38.63  ? 47  TRP C N   1 
ATOM   3656 C CA  . TRP C 3 47  ? -1.075  -23.453 -28.521 1.00 34.31  ? 47  TRP C CA  1 
ATOM   3657 C C   . TRP C 3 47  ? -0.706  -23.000 -29.928 1.00 36.22  ? 47  TRP C C   1 
ATOM   3658 O O   . TRP C 3 47  ? 0.323   -22.352 -30.135 1.00 34.39  ? 47  TRP C O   1 
ATOM   3659 C CB  . TRP C 3 47  ? -1.620  -22.278 -27.713 1.00 36.04  ? 47  TRP C CB  1 
ATOM   3660 C CG  . TRP C 3 47  ? -2.628  -21.473 -28.467 1.00 27.84  ? 47  TRP C CG  1 
ATOM   3661 C CD1 . TRP C 3 47  ? -3.961  -21.735 -28.588 1.00 40.33  ? 47  TRP C CD1 1 
ATOM   3662 C CD2 . TRP C 3 47  ? -2.385  -20.275 -29.214 1.00 32.15  ? 47  TRP C CD2 1 
ATOM   3663 N NE1 . TRP C 3 47  ? -4.565  -20.774 -29.362 1.00 40.64  ? 47  TRP C NE1 1 
ATOM   3664 C CE2 . TRP C 3 47  ? -3.618  -19.866 -29.759 1.00 42.84  ? 47  TRP C CE2 1 
ATOM   3665 C CE3 . TRP C 3 47  ? -1.244  -19.510 -29.476 1.00 30.96  ? 47  TRP C CE3 1 
ATOM   3666 C CZ2 . TRP C 3 47  ? -3.744  -18.724 -30.549 1.00 32.59  ? 47  TRP C CZ2 1 
ATOM   3667 C CZ3 . TRP C 3 47  ? -1.370  -18.376 -30.261 1.00 29.43  ? 47  TRP C CZ3 1 
ATOM   3668 C CH2 . TRP C 3 47  ? -2.611  -17.994 -30.788 1.00 30.11  ? 47  TRP C CH2 1 
ATOM   3669 N N   . VAL C 3 48  ? -1.558  -23.331 -30.896 1.00 37.27  ? 48  VAL C N   1 
ATOM   3670 C CA  . VAL C 3 48  ? -1.247  -23.092 -32.301 1.00 31.87  ? 48  VAL C CA  1 
ATOM   3671 C C   . VAL C 3 48  ? -2.046  -21.916 -32.841 1.00 36.93  ? 48  VAL C C   1 
ATOM   3672 O O   . VAL C 3 48  ? -1.470  -20.936 -33.324 1.00 39.62  ? 48  VAL C O   1 
ATOM   3673 C CB  . VAL C 3 48  ? -1.502  -24.353 -33.143 1.00 30.23  ? 48  VAL C CB  1 
ATOM   3674 C CG1 . VAL C 3 48  ? -1.164  -24.088 -34.598 1.00 33.41  ? 48  VAL C CG1 1 
ATOM   3675 C CG2 . VAL C 3 48  ? -0.690  -25.516 -32.602 1.00 28.31  ? 48  VAL C CG2 1 
ATOM   3676 N N   . SER C 3 49  ? -3.373  -22.002 -32.767 1.00 40.13  ? 49  SER C N   1 
ATOM   3677 C CA  . SER C 3 49  ? -4.218  -20.956 -33.329 1.00 44.27  ? 49  SER C CA  1 
ATOM   3678 C C   . SER C 3 49  ? -5.581  -20.989 -32.652 1.00 36.78  ? 49  SER C C   1 
ATOM   3679 O O   . SER C 3 49  ? -5.930  -21.944 -31.954 1.00 40.36  ? 49  SER C O   1 
ATOM   3680 C CB  . SER C 3 49  ? -4.361  -21.110 -34.845 1.00 45.02  ? 49  SER C CB  1 
ATOM   3681 O OG  . SER C 3 49  ? -5.576  -21.751 -35.179 1.00 53.56  ? 49  SER C OG  1 
ATOM   3682 N N   . VAL C 3 50  ? -6.351  -19.922 -32.872 1.00 31.04  ? 50  VAL C N   1 
ATOM   3683 C CA  . VAL C 3 50  ? -7.679  -19.772 -32.287 1.00 27.12  ? 50  VAL C CA  1 
ATOM   3684 C C   . VAL C 3 50  ? -8.567  -19.027 -33.276 1.00 27.95  ? 50  VAL C C   1 
ATOM   3685 O O   . VAL C 3 50  ? -8.104  -18.160 -34.023 1.00 30.29  ? 50  VAL C O   1 
ATOM   3686 C CB  . VAL C 3 50  ? -7.621  -19.036 -30.925 1.00 31.47  ? 50  VAL C CB  1 
ATOM   3687 C CG1 . VAL C 3 50  ? -7.116  -17.610 -31.101 1.00 25.54  ? 50  VAL C CG1 1 
ATOM   3688 C CG2 . VAL C 3 50  ? -8.982  -19.041 -30.245 1.00 29.52  ? 50  VAL C CG2 1 
ATOM   3689 N N   . ILE C 3 51  ? -9.850  -19.384 -33.289 1.00 33.48  ? 51  ILE C N   1 
ATOM   3690 C CA  . ILE C 3 51  ? -10.869 -18.651 -34.031 1.00 28.43  ? 51  ILE C CA  1 
ATOM   3691 C C   . ILE C 3 51  ? -11.953 -18.222 -33.050 1.00 30.00  ? 51  ILE C C   1 
ATOM   3692 O O   . ILE C 3 51  ? -12.421 -19.029 -32.238 1.00 26.97  ? 51  ILE C O   1 
ATOM   3693 C CB  . ILE C 3 51  ? -11.454 -19.481 -35.192 1.00 28.85  ? 51  ILE C CB  1 
ATOM   3694 C CG1 . ILE C 3 51  ? -12.521 -18.679 -35.939 1.00 24.73  ? 51  ILE C CG1 1 
ATOM   3695 C CG2 . ILE C 3 51  ? -12.016 -20.807 -34.701 1.00 29.25  ? 51  ILE C CG2 1 
ATOM   3696 C CD1 . ILE C 3 51  ? -13.045 -19.372 -37.177 1.00 23.14  ? 51  ILE C CD1 1 
ATOM   3697 N N   . TYR C 3 52  ? -12.327 -16.947 -33.108 1.00 37.76  ? 52  TYR C N   1 
ATOM   3698 C CA  . TYR C 3 52  ? -13.290 -16.392 -32.171 1.00 32.71  ? 52  TYR C CA  1 
ATOM   3699 C C   . TYR C 3 52  ? -14.717 -16.737 -32.589 1.00 37.61  ? 52  TYR C C   1 
ATOM   3700 O O   . TYR C 3 52  ? -14.982 -17.175 -33.711 1.00 40.75  ? 52  TYR C O   1 
ATOM   3701 C CB  . TYR C 3 52  ? -13.131 -14.875 -32.068 1.00 34.45  ? 52  TYR C CB  1 
ATOM   3702 C CG  . TYR C 3 52  ? -11.963 -14.421 -31.222 1.00 31.66  ? 52  TYR C CG  1 
ATOM   3703 C CD1 . TYR C 3 52  ? -11.057 -15.335 -30.700 1.00 34.99  ? 52  TYR C CD1 1 
ATOM   3704 C CD2 . TYR C 3 52  ? -11.774 -13.076 -30.934 1.00 33.72  ? 52  TYR C CD2 1 
ATOM   3705 C CE1 . TYR C 3 52  ? -9.993  -14.922 -29.921 1.00 34.96  ? 52  TYR C CE1 1 
ATOM   3706 C CE2 . TYR C 3 52  ? -10.714 -12.654 -30.156 1.00 38.96  ? 52  TYR C CE2 1 
ATOM   3707 C CZ  . TYR C 3 52  ? -9.827  -13.580 -29.653 1.00 32.78  ? 52  TYR C CZ  1 
ATOM   3708 O OH  . TYR C 3 52  ? -8.770  -13.160 -28.879 1.00 43.85  ? 52  TYR C OH  1 
ATOM   3709 N N   . SER C 3 53  ? -15.648 -16.528 -31.654 1.00 40.78  ? 53  SER C N   1 
ATOM   3710 C CA  . SER C 3 53  ? -17.062 -16.693 -31.974 1.00 40.36  ? 53  SER C CA  1 
ATOM   3711 C C   . SER C 3 53  ? -17.493 -15.711 -33.056 1.00 31.19  ? 53  SER C C   1 
ATOM   3712 O O   . SER C 3 53  ? -18.313 -16.046 -33.919 1.00 35.89  ? 53  SER C O   1 
ATOM   3713 C CB  . SER C 3 53  ? -17.910 -16.516 -30.713 1.00 43.75  ? 53  SER C CB  1 
ATOM   3714 O OG  . SER C 3 53  ? -17.648 -15.270 -30.089 1.00 34.02  ? 53  SER C OG  1 
ATOM   3715 N N   . GLY C 3 54  ? -16.948 -14.493 -33.026 1.00 28.10  ? 54  GLY C N   1 
ATOM   3716 C CA  . GLY C 3 54  ? -17.239 -13.515 -34.060 1.00 34.57  ? 54  GLY C CA  1 
ATOM   3717 C C   . GLY C 3 54  ? -16.568 -13.802 -35.386 1.00 42.09  ? 54  GLY C C   1 
ATOM   3718 O O   . GLY C 3 54  ? -16.995 -13.259 -36.412 1.00 31.75  ? 54  GLY C O   1 
ATOM   3719 N N   . GLY C 3 55  ? -15.533 -14.641 -35.390 1.00 39.55  ? 55  GLY C N   1 
ATOM   3720 C CA  . GLY C 3 55  ? -14.872 -15.061 -36.610 1.00 37.30  ? 55  GLY C CA  1 
ATOM   3721 C C   . GLY C 3 55  ? -13.433 -14.624 -36.741 1.00 43.81  ? 55  GLY C C   1 
ATOM   3722 O O   . GLY C 3 55  ? -12.775 -15.016 -37.717 1.00 43.70  ? 55  GLY C O   1 
ATOM   3723 N N   . SER C 3 56  ? -12.920 -13.829 -35.808 1.00 43.04  ? 56  SER C N   1 
ATOM   3724 C CA  . SER C 3 56  ? -11.528 -13.409 -35.857 1.00 42.50  ? 56  SER C CA  1 
ATOM   3725 C C   . SER C 3 56  ? -10.601 -14.587 -35.578 1.00 38.17  ? 56  SER C C   1 
ATOM   3726 O O   . SER C 3 56  ? -10.905 -15.475 -34.778 1.00 31.88  ? 56  SER C O   1 
ATOM   3727 C CB  . SER C 3 56  ? -11.272 -12.287 -34.852 1.00 38.41  ? 56  SER C CB  1 
ATOM   3728 O OG  . SER C 3 56  ? -12.046 -11.141 -35.158 1.00 52.81  ? 56  SER C OG  1 
ATOM   3729 N N   . THR C 3 57  ? -9.451  -14.584 -36.251 1.00 38.64  ? 57  THR C N   1 
ATOM   3730 C CA  . THR C 3 57  ? -8.482  -15.668 -36.163 1.00 38.64  ? 57  THR C CA  1 
ATOM   3731 C C   . THR C 3 57  ? -7.133  -15.130 -35.707 1.00 40.02  ? 57  THR C C   1 
ATOM   3732 O O   . THR C 3 57  ? -6.722  -14.035 -36.105 1.00 35.98  ? 57  THR C O   1 
ATOM   3733 C CB  . THR C 3 57  ? -8.317  -16.384 -37.509 1.00 39.54  ? 57  THR C CB  1 
ATOM   3734 O OG1 . THR C 3 57  ? -7.857  -15.451 -38.495 1.00 41.72  ? 57  THR C OG1 1 
ATOM   3735 C CG2 . THR C 3 57  ? -9.641  -16.981 -37.962 1.00 40.09  ? 57  THR C CG2 1 
ATOM   3736 N N   . PHE C 3 58  ? -6.453  -15.909 -34.869 1.00 39.08  ? 58  PHE C N   1 
ATOM   3737 C CA  . PHE C 3 58  ? -5.119  -15.577 -34.394 1.00 42.90  ? 58  PHE C CA  1 
ATOM   3738 C C   . PHE C 3 58  ? -4.260  -16.833 -34.420 1.00 47.94  ? 58  PHE C C   1 
ATOM   3739 O O   . PHE C 3 58  ? -4.766  -17.950 -34.286 1.00 46.19  ? 58  PHE C O   1 
ATOM   3740 C CB  . PHE C 3 58  ? -5.162  -14.977 -32.985 1.00 29.41  ? 58  PHE C CB  1 
ATOM   3741 C CG  . PHE C 3 58  ? -6.014  -13.746 -32.885 1.00 30.38  ? 58  PHE C CG  1 
ATOM   3742 C CD1 . PHE C 3 58  ? -5.487  -12.499 -33.169 1.00 28.82  ? 58  PHE C CD1 1 
ATOM   3743 C CD2 . PHE C 3 58  ? -7.346  -13.837 -32.517 1.00 38.03  ? 58  PHE C CD2 1 
ATOM   3744 C CE1 . PHE C 3 58  ? -6.269  -11.363 -33.083 1.00 26.25  ? 58  PHE C CE1 1 
ATOM   3745 C CE2 . PHE C 3 58  ? -8.134  -12.706 -32.429 1.00 31.65  ? 58  PHE C CE2 1 
ATOM   3746 C CZ  . PHE C 3 58  ? -7.595  -11.467 -32.713 1.00 33.28  ? 58  PHE C CZ  1 
ATOM   3747 N N   . TYR C 3 59  ? -2.954  -16.640 -34.594 1.00 50.12  ? 59  TYR C N   1 
ATOM   3748 C CA  . TYR C 3 59  ? -2.032  -17.750 -34.778 1.00 48.72  ? 59  TYR C CA  1 
ATOM   3749 C C   . TYR C 3 59  ? -0.775  -17.517 -33.951 1.00 53.64  ? 59  TYR C C   1 
ATOM   3750 O O   . TYR C 3 59  ? -0.453  -16.388 -33.573 1.00 51.41  ? 59  TYR C O   1 
ATOM   3751 C CB  . TYR C 3 59  ? -1.658  -17.931 -36.257 1.00 45.68  ? 59  TYR C CB  1 
ATOM   3752 C CG  . TYR C 3 59  ? -2.844  -17.997 -37.193 1.00 46.72  ? 59  TYR C CG  1 
ATOM   3753 C CD1 . TYR C 3 59  ? -3.389  -16.841 -37.739 1.00 31.06  ? 59  TYR C CD1 1 
ATOM   3754 C CD2 . TYR C 3 59  ? -3.417  -19.214 -37.536 1.00 39.10  ? 59  TYR C CD2 1 
ATOM   3755 C CE1 . TYR C 3 59  ? -4.472  -16.896 -38.593 1.00 36.94  ? 59  TYR C CE1 1 
ATOM   3756 C CE2 . TYR C 3 59  ? -4.501  -19.280 -38.389 1.00 34.19  ? 59  TYR C CE2 1 
ATOM   3757 C CZ  . TYR C 3 59  ? -5.024  -18.118 -38.916 1.00 41.30  ? 59  TYR C CZ  1 
ATOM   3758 O OH  . TYR C 3 59  ? -6.104  -18.176 -39.768 1.00 32.16  ? 59  TYR C OH  1 
ATOM   3759 N N   . ALA C 3 60  ? -0.071  -18.609 -33.667 1.00 54.21  ? 60  ALA C N   1 
ATOM   3760 C CA  . ALA C 3 60  ? 1.219   -18.531 -32.999 1.00 44.31  ? 60  ALA C CA  1 
ATOM   3761 C C   . ALA C 3 60  ? 2.301   -18.107 -33.986 1.00 55.55  ? 60  ALA C C   1 
ATOM   3762 O O   . ALA C 3 60  ? 2.233   -18.407 -35.181 1.00 54.57  ? 60  ALA C O   1 
ATOM   3763 C CB  . ALA C 3 60  ? 1.581   -19.875 -32.367 1.00 32.79  ? 60  ALA C CB  1 
ATOM   3764 N N   . ASP C 3 61  ? 3.317   -17.411 -33.466 1.00 56.57  ? 61  ASP C N   1 
ATOM   3765 C CA  . ASP C 3 61  ? 4.368   -16.873 -34.325 1.00 62.82  ? 61  ASP C CA  1 
ATOM   3766 C C   . ASP C 3 61  ? 5.104   -17.968 -35.087 1.00 61.78  ? 61  ASP C C   1 
ATOM   3767 O O   . ASP C 3 61  ? 5.547   -17.742 -36.219 1.00 55.21  ? 61  ASP C O   1 
ATOM   3768 C CB  . ASP C 3 61  ? 5.358   -16.053 -33.496 1.00 70.66  ? 61  ASP C CB  1 
ATOM   3769 C CG  . ASP C 3 61  ? 4.864   -14.648 -33.222 1.00 77.96  ? 61  ASP C CG  1 
ATOM   3770 O OD1 . ASP C 3 61  ? 4.304   -14.023 -34.147 1.00 72.62  ? 61  ASP C OD1 1 
ATOM   3771 O OD2 . ASP C 3 61  ? 5.033   -14.168 -32.081 1.00 88.89  ? 61  ASP C OD2 1 
ATOM   3772 N N   . SER C 3 62  ? 5.249   -19.153 -34.489 1.00 51.47  ? 62  SER C N   1 
ATOM   3773 C CA  . SER C 3 62  ? 5.938   -20.241 -35.177 1.00 41.61  ? 62  SER C CA  1 
ATOM   3774 C C   . SER C 3 62  ? 5.163   -20.696 -36.407 1.00 47.32  ? 62  SER C C   1 
ATOM   3775 O O   . SER C 3 62  ? 5.759   -21.077 -37.421 1.00 55.21  ? 62  SER C O   1 
ATOM   3776 C CB  . SER C 3 62  ? 6.163   -21.411 -34.219 1.00 36.18  ? 62  SER C CB  1 
ATOM   3777 O OG  . SER C 3 62  ? 4.931   -21.925 -33.746 1.00 39.97  ? 62  SER C OG  1 
ATOM   3778 N N   . VAL C 3 63  ? 3.834   -20.659 -36.336 1.00 53.28  ? 63  VAL C N   1 
ATOM   3779 C CA  . VAL C 3 63  ? 2.969   -21.149 -37.404 1.00 42.13  ? 63  VAL C CA  1 
ATOM   3780 C C   . VAL C 3 63  ? 2.329   -20.026 -38.204 1.00 44.10  ? 63  VAL C C   1 
ATOM   3781 O O   . VAL C 3 63  ? 1.554   -20.310 -39.130 1.00 49.91  ? 63  VAL C O   1 
ATOM   3782 C CB  . VAL C 3 63  ? 1.887   -22.099 -36.853 1.00 41.75  ? 63  VAL C CB  1 
ATOM   3783 C CG1 . VAL C 3 63  ? 2.496   -23.074 -35.851 1.00 44.99  ? 63  VAL C CG1 1 
ATOM   3784 C CG2 . VAL C 3 63  ? 0.737   -21.313 -36.223 1.00 48.84  ? 63  VAL C CG2 1 
ATOM   3785 N N   . LYS C 3 64  ? 2.632   -18.766 -37.893 1.00 36.57  ? 64  LYS C N   1 
ATOM   3786 C CA  . LYS C 3 64  ? 2.040   -17.658 -38.628 1.00 36.04  ? 64  LYS C CA  1 
ATOM   3787 C C   . LYS C 3 64  ? 2.465   -17.687 -40.091 1.00 39.56  ? 64  LYS C C   1 
ATOM   3788 O O   . LYS C 3 64  ? 3.549   -18.161 -40.441 1.00 60.16  ? 64  LYS C O   1 
ATOM   3789 C CB  . LYS C 3 64  ? 2.441   -16.318 -38.004 1.00 54.70  ? 64  LYS C CB  1 
ATOM   3790 C CG  . LYS C 3 64  ? 1.537   -15.852 -36.878 1.00 72.84  ? 64  LYS C CG  1 
ATOM   3791 C CD  . LYS C 3 64  ? 1.964   -14.485 -36.372 1.00 81.37  ? 64  LYS C CD  1 
ATOM   3792 C CE  . LYS C 3 64  ? 1.082   -14.012 -35.231 1.00 78.63  ? 64  LYS C CE  1 
ATOM   3793 N NZ  . LYS C 3 64  ? 1.495   -12.670 -34.736 1.00 83.04  ? 64  LYS C NZ  1 
ATOM   3794 N N   . GLY C 3 65  ? 1.586   -17.178 -40.955 1.00 27.43  ? 65  GLY C N   1 
ATOM   3795 C CA  . GLY C 3 65  ? 1.826   -17.162 -42.382 1.00 42.46  ? 65  GLY C CA  1 
ATOM   3796 C C   . GLY C 3 65  ? 1.744   -18.505 -43.069 1.00 50.21  ? 65  GLY C C   1 
ATOM   3797 O O   . GLY C 3 65  ? 1.715   -18.545 -44.306 1.00 36.28  ? 65  GLY C O   1 
ATOM   3798 N N   . ARG C 3 66  ? 1.700   -19.604 -42.320 1.00 48.23  ? 66  ARG C N   1 
ATOM   3799 C CA  . ARG C 3 66  ? 1.628   -20.947 -42.878 1.00 44.77  ? 66  ARG C CA  1 
ATOM   3800 C C   . ARG C 3 66  ? 0.314   -21.643 -42.563 1.00 44.77  ? 66  ARG C C   1 
ATOM   3801 O O   . ARG C 3 66  ? -0.294  -22.250 -43.449 1.00 41.39  ? 66  ARG C O   1 
ATOM   3802 C CB  . ARG C 3 66  ? 2.793   -21.796 -42.351 1.00 56.35  ? 66  ARG C CB  1 
ATOM   3803 C CG  . ARG C 3 66  ? 4.173   -21.228 -42.625 1.00 45.11  ? 66  ARG C CG  1 
ATOM   3804 C CD  . ARG C 3 66  ? 5.233   -22.204 -42.157 1.00 41.28  ? 66  ARG C CD  1 
ATOM   3805 N NE  . ARG C 3 66  ? 5.085   -22.518 -40.741 1.00 42.28  ? 66  ARG C NE  1 
ATOM   3806 C CZ  . ARG C 3 66  ? 5.379   -23.692 -40.200 1.00 39.49  ? 66  ARG C CZ  1 
ATOM   3807 N NH1 . ARG C 3 66  ? 5.815   -24.701 -40.935 1.00 39.70  ? 66  ARG C NH1 1 
ATOM   3808 N NH2 . ARG C 3 66  ? 5.221   -23.861 -38.890 1.00 41.36  ? 66  ARG C NH2 1 
ATOM   3809 N N   . PHE C 3 67  ? -0.138  -21.575 -41.315 1.00 45.77  ? 67  PHE C N   1 
ATOM   3810 C CA  . PHE C 3 67  ? -1.361  -22.246 -40.904 1.00 41.51  ? 67  PHE C CA  1 
ATOM   3811 C C   . PHE C 3 67  ? -2.556  -21.317 -41.069 1.00 41.87  ? 67  PHE C C   1 
ATOM   3812 O O   . PHE C 3 67  ? -2.432  -20.091 -41.006 1.00 49.72  ? 67  PHE C O   1 
ATOM   3813 C CB  . PHE C 3 67  ? -1.271  -22.718 -39.450 1.00 37.68  ? 67  PHE C CB  1 
ATOM   3814 C CG  . PHE C 3 67  ? -0.318  -23.866 -39.231 1.00 41.56  ? 67  PHE C CG  1 
ATOM   3815 C CD1 . PHE C 3 67  ? 0.532   -24.296 -40.237 1.00 41.07  ? 67  PHE C CD1 1 
ATOM   3816 C CD2 . PHE C 3 67  ? -0.288  -24.525 -38.013 1.00 41.02  ? 67  PHE C CD2 1 
ATOM   3817 C CE1 . PHE C 3 67  ? 1.403   -25.347 -40.029 1.00 45.35  ? 67  PHE C CE1 1 
ATOM   3818 C CE2 . PHE C 3 67  ? 0.581   -25.578 -37.798 1.00 52.68  ? 67  PHE C CE2 1 
ATOM   3819 C CZ  . PHE C 3 67  ? 1.426   -25.990 -38.808 1.00 43.80  ? 67  PHE C CZ  1 
ATOM   3820 N N   . THR C 3 68  ? -3.724  -21.918 -41.283 1.00 42.26  ? 68  THR C N   1 
ATOM   3821 C CA  . THR C 3 68  ? -4.967  -21.171 -41.435 1.00 37.22  ? 68  THR C CA  1 
ATOM   3822 C C   . THR C 3 68  ? -6.084  -21.945 -40.756 1.00 40.20  ? 68  THR C C   1 
ATOM   3823 O O   . THR C 3 68  ? -6.381  -23.078 -41.145 1.00 40.03  ? 68  THR C O   1 
ATOM   3824 C CB  . THR C 3 68  ? -5.300  -20.935 -42.910 1.00 29.25  ? 68  THR C CB  1 
ATOM   3825 O OG1 . THR C 3 68  ? -4.376  -19.989 -43.464 1.00 37.79  ? 68  THR C OG1 1 
ATOM   3826 C CG2 . THR C 3 68  ? -6.719  -20.406 -43.058 1.00 31.46  ? 68  THR C CG2 1 
ATOM   3827 N N   . ILE C 3 69  ? -6.692  -21.340 -39.747 1.00 33.40  ? 69  ILE C N   1 
ATOM   3828 C CA  . ILE C 3 69  ? -7.810  -21.948 -39.039 1.00 30.55  ? 69  ILE C CA  1 
ATOM   3829 C C   . ILE C 3 69  ? -9.106  -21.445 -39.658 1.00 35.28  ? 69  ILE C C   1 
ATOM   3830 O O   . ILE C 3 69  ? -9.204  -20.287 -40.083 1.00 33.30  ? 69  ILE C O   1 
ATOM   3831 C CB  . ILE C 3 69  ? -7.740  -21.641 -37.530 1.00 26.18  ? 69  ILE C CB  1 
ATOM   3832 C CG1 . ILE C 3 69  ? -8.812  -22.423 -36.767 1.00 28.43  ? 69  ILE C CG1 1 
ATOM   3833 C CG2 . ILE C 3 69  ? -7.873  -20.148 -37.268 1.00 29.52  ? 69  ILE C CG2 1 
ATOM   3834 C CD1 . ILE C 3 69  ? -8.743  -22.246 -35.269 1.00 31.58  ? 69  ILE C CD1 1 
ATOM   3835 N N   . SER C 3 70  ? -10.095 -22.330 -39.742 1.00 29.45  ? 70  SER C N   1 
ATOM   3836 C CA  . SER C 3 70  ? -11.388 -21.987 -40.316 1.00 25.61  ? 70  SER C CA  1 
ATOM   3837 C C   . SER C 3 70  ? -12.416 -22.985 -39.807 1.00 33.08  ? 70  SER C C   1 
ATOM   3838 O O   . SER C 3 70  ? -12.076 -24.004 -39.202 1.00 33.54  ? 70  SER C O   1 
ATOM   3839 C CB  . SER C 3 70  ? -11.339 -21.979 -41.847 1.00 25.34  ? 70  SER C CB  1 
ATOM   3840 O OG  . SER C 3 70  ? -11.045 -23.270 -42.353 1.00 46.03  ? 70  SER C OG  1 
ATOM   3841 N N   . ARG C 3 71  ? -13.685 -22.675 -40.058 1.00 40.28  ? 71  ARG C N   1 
ATOM   3842 C CA  . ARG C 3 71  ? -14.782 -23.539 -39.652 1.00 40.73  ? 71  ARG C CA  1 
ATOM   3843 C C   . ARG C 3 71  ? -15.845 -23.556 -40.737 1.00 30.70  ? 71  ARG C C   1 
ATOM   3844 O O   . ARG C 3 71  ? -15.985 -22.604 -41.510 1.00 28.14  ? 71  ARG C O   1 
ATOM   3845 C CB  . ARG C 3 71  ? -15.401 -23.089 -38.321 1.00 26.18  ? 71  ARG C CB  1 
ATOM   3846 C CG  . ARG C 3 71  ? -15.733 -21.610 -38.263 1.00 14.67  ? 71  ARG C CG  1 
ATOM   3847 C CD  . ARG C 3 71  ? -16.798 -21.333 -37.218 1.00 39.88  ? 71  ARG C CD  1 
ATOM   3848 N NE  . ARG C 3 71  ? -16.957 -19.908 -36.951 1.00 31.98  ? 71  ARG C NE  1 
ATOM   3849 C CZ  . ARG C 3 71  ? -16.462 -19.288 -35.889 1.00 32.27  ? 71  ARG C CZ  1 
ATOM   3850 N NH1 . ARG C 3 71  ? -15.769 -19.940 -34.969 1.00 29.26  ? 71  ARG C NH1 1 
ATOM   3851 N NH2 . ARG C 3 71  ? -16.673 -17.983 -35.742 1.00 35.09  ? 71  ARG C NH2 1 
ATOM   3852 N N   . ASP C 3 72  ? -16.593 -24.656 -40.786 1.00 38.48  ? 72  ASP C N   1 
ATOM   3853 C CA  . ASP C 3 72  ? -17.709 -24.831 -41.714 1.00 40.70  ? 72  ASP C CA  1 
ATOM   3854 C C   . ASP C 3 72  ? -18.903 -25.292 -40.884 1.00 43.20  ? 72  ASP C C   1 
ATOM   3855 O O   . ASP C 3 72  ? -19.033 -26.483 -40.586 1.00 48.96  ? 72  ASP C O   1 
ATOM   3856 C CB  . ASP C 3 72  ? -17.364 -25.833 -42.813 1.00 45.05  ? 72  ASP C CB  1 
ATOM   3857 C CG  . ASP C 3 72  ? -18.417 -25.897 -43.903 1.00 55.15  ? 72  ASP C CG  1 
ATOM   3858 O OD1 . ASP C 3 72  ? -19.381 -25.103 -43.856 1.00 64.06  ? 72  ASP C OD1 1 
ATOM   3859 O OD2 . ASP C 3 72  ? -18.278 -26.743 -44.811 1.00 59.03  ? 72  ASP C OD2 1 
ATOM   3860 N N   . ASN C 3 73  ? -19.771 -24.347 -40.509 1.00 42.40  ? 73  ASN C N   1 
ATOM   3861 C CA  . ASN C 3 73  ? -20.877 -24.679 -39.617 1.00 48.01  ? 73  ASN C CA  1 
ATOM   3862 C C   . ASN C 3 73  ? -21.847 -25.661 -40.260 1.00 47.24  ? 73  ASN C C   1 
ATOM   3863 O O   . ASN C 3 73  ? -22.542 -26.398 -39.551 1.00 51.82  ? 73  ASN C O   1 
ATOM   3864 C CB  . ASN C 3 73  ? -21.615 -23.410 -39.191 1.00 39.30  ? 73  ASN C CB  1 
ATOM   3865 C CG  . ASN C 3 73  ? -22.297 -23.557 -37.839 1.00 62.75  ? 73  ASN C CG  1 
ATOM   3866 O OD1 . ASN C 3 73  ? -22.483 -22.578 -37.118 1.00 71.70  ? 73  ASN C OD1 1 
ATOM   3867 N ND2 . ASN C 3 73  ? -22.659 -24.785 -37.484 1.00 44.03  ? 73  ASN C ND2 1 
ATOM   3868 N N   . SER C 3 74  ? -21.910 -25.690 -41.594 1.00 43.53  ? 74  SER C N   1 
ATOM   3869 C CA  . SER C 3 74  ? -22.780 -26.643 -42.273 1.00 39.76  ? 74  SER C CA  1 
ATOM   3870 C C   . SER C 3 74  ? -22.368 -28.084 -42.007 1.00 45.54  ? 74  SER C C   1 
ATOM   3871 O O   . SER C 3 74  ? -23.192 -28.992 -42.161 1.00 46.02  ? 74  SER C O   1 
ATOM   3872 C CB  . SER C 3 74  ? -22.791 -26.368 -43.778 1.00 44.69  ? 74  SER C CB  1 
ATOM   3873 O OG  . SER C 3 74  ? -21.487 -26.456 -44.326 1.00 62.59  ? 74  SER C OG  1 
ATOM   3874 N N   . LYS C 3 75  ? -21.116 -28.315 -41.613 1.00 52.71  ? 75  LYS C N   1 
ATOM   3875 C CA  . LYS C 3 75  ? -20.649 -29.643 -41.247 1.00 43.11  ? 75  LYS C CA  1 
ATOM   3876 C C   . LYS C 3 75  ? -20.197 -29.730 -39.797 1.00 50.19  ? 75  LYS C C   1 
ATOM   3877 O O   . LYS C 3 75  ? -19.725 -30.793 -39.375 1.00 46.87  ? 75  LYS C O   1 
ATOM   3878 C CB  . LYS C 3 75  ? -19.505 -30.079 -42.172 1.00 33.39  ? 75  LYS C CB  1 
ATOM   3879 C CG  . LYS C 3 75  ? -19.686 -29.632 -43.612 1.00 42.29  ? 75  LYS C CG  1 
ATOM   3880 C CD  . LYS C 3 75  ? -19.039 -30.599 -44.584 1.00 57.03  ? 75  LYS C CD  1 
ATOM   3881 C CE  . LYS C 3 75  ? -19.046 -30.035 -45.995 1.00 64.63  ? 75  LYS C CE  1 
ATOM   3882 N NZ  . LYS C 3 75  ? -18.394 -30.959 -46.966 1.00 38.37  ? 75  LYS C NZ  1 
ATOM   3883 N N   . SER C 3 76  ? -20.335 -28.648 -39.027 1.00 39.74  ? 76  SER C N   1 
ATOM   3884 C CA  . SER C 3 76  ? -19.938 -28.606 -37.619 1.00 42.07  ? 76  SER C CA  1 
ATOM   3885 C C   . SER C 3 76  ? -18.490 -29.063 -37.454 1.00 37.13  ? 76  SER C C   1 
ATOM   3886 O O   . SER C 3 76  ? -18.152 -29.852 -36.568 1.00 30.67  ? 76  SER C O   1 
ATOM   3887 C CB  . SER C 3 76  ? -20.884 -29.442 -36.755 1.00 39.92  ? 76  SER C CB  1 
ATOM   3888 O OG  . SER C 3 76  ? -21.283 -28.730 -35.596 1.00 37.92  ? 76  SER C OG  1 
ATOM   3889 N N   . THR C 3 77  ? -17.630 -28.555 -38.334 1.00 34.02  ? 77  THR C N   1 
ATOM   3890 C CA  . THR C 3 77  ? -16.249 -29.001 -38.433 1.00 35.08  ? 77  THR C CA  1 
ATOM   3891 C C   . THR C 3 77  ? -15.306 -27.810 -38.348 1.00 34.72  ? 77  THR C C   1 
ATOM   3892 O O   . THR C 3 77  ? -15.571 -26.752 -38.926 1.00 32.16  ? 77  THR C O   1 
ATOM   3893 C CB  . THR C 3 77  ? -16.010 -29.765 -39.744 1.00 42.08  ? 77  THR C CB  1 
ATOM   3894 O OG1 . THR C 3 77  ? -16.948 -30.844 -39.845 1.00 45.97  ? 77  THR C OG1 1 
ATOM   3895 C CG2 . THR C 3 77  ? -14.599 -30.326 -39.792 1.00 28.86  ? 77  THR C CG2 1 
ATOM   3896 N N   . LEU C 3 78  ? -14.208 -27.992 -37.618 1.00 41.72  ? 78  LEU C N   1 
ATOM   3897 C CA  . LEU C 3 78  ? -13.142 -27.007 -37.509 1.00 34.47  ? 78  LEU C CA  1 
ATOM   3898 C C   . LEU C 3 78  ? -11.936 -27.494 -38.301 1.00 29.01  ? 78  LEU C C   1 
ATOM   3899 O O   . LEU C 3 78  ? -11.510 -28.644 -38.144 1.00 34.41  ? 78  LEU C O   1 
ATOM   3900 C CB  . LEU C 3 78  ? -12.759 -26.778 -36.046 1.00 26.28  ? 78  LEU C CB  1 
ATOM   3901 C CG  . LEU C 3 78  ? -11.643 -25.769 -35.781 1.00 29.38  ? 78  LEU C CG  1 
ATOM   3902 C CD1 . LEU C 3 78  ? -12.148 -24.346 -35.956 1.00 31.79  ? 78  LEU C CD1 1 
ATOM   3903 C CD2 . LEU C 3 78  ? -11.055 -25.975 -34.395 1.00 33.99  ? 78  LEU C CD2 1 
ATOM   3904 N N   . TYR C 3 79  ? -11.388 -26.624 -39.144 1.00 28.76  ? 79  TYR C N   1 
ATOM   3905 C CA  . TYR C 3 79  ? -10.289 -26.977 -40.029 1.00 31.87  ? 79  TYR C CA  1 
ATOM   3906 C C   . TYR C 3 79  ? -9.007  -26.260 -39.622 1.00 33.89  ? 79  TYR C C   1 
ATOM   3907 O O   . TYR C 3 79  ? -9.038  -25.190 -39.008 1.00 33.73  ? 79  TYR C O   1 
ATOM   3908 C CB  . TYR C 3 79  ? -10.619 -26.633 -41.485 1.00 26.47  ? 79  TYR C CB  1 
ATOM   3909 C CG  . TYR C 3 79  ? -11.798 -27.387 -42.052 1.00 35.91  ? 79  TYR C CG  1 
ATOM   3910 C CD1 . TYR C 3 79  ? -11.714 -28.747 -42.320 1.00 37.44  ? 79  TYR C CD1 1 
ATOM   3911 C CD2 . TYR C 3 79  ? -12.992 -26.737 -42.335 1.00 39.91  ? 79  TYR C CD2 1 
ATOM   3912 C CE1 . TYR C 3 79  ? -12.789 -29.440 -42.844 1.00 55.51  ? 79  TYR C CE1 1 
ATOM   3913 C CE2 . TYR C 3 79  ? -14.072 -27.420 -42.860 1.00 47.49  ? 79  TYR C CE2 1 
ATOM   3914 C CZ  . TYR C 3 79  ? -13.965 -28.772 -43.112 1.00 52.22  ? 79  TYR C CZ  1 
ATOM   3915 O OH  . TYR C 3 79  ? -15.038 -29.458 -43.635 1.00 44.20  ? 79  TYR C OH  1 
ATOM   3916 N N   . LEU C 3 80  ? -7.875  -26.871 -39.976 1.00 32.43  ? 80  LEU C N   1 
ATOM   3917 C CA  . LEU C 3 80  ? -6.554  -26.261 -39.813 1.00 30.54  ? 80  LEU C CA  1 
ATOM   3918 C C   . LEU C 3 80  ? -5.740  -26.598 -41.059 1.00 25.88  ? 80  LEU C C   1 
ATOM   3919 O O   . LEU C 3 80  ? -5.234  -27.716 -41.193 1.00 31.10  ? 80  LEU C O   1 
ATOM   3920 C CB  . LEU C 3 80  ? -5.858  -26.748 -38.549 1.00 25.19  ? 80  LEU C CB  1 
ATOM   3921 C CG  . LEU C 3 80  ? -4.476  -26.145 -38.278 1.00 25.66  ? 80  LEU C CG  1 
ATOM   3922 C CD1 . LEU C 3 80  ? -4.568  -24.635 -38.112 1.00 28.26  ? 80  LEU C CD1 1 
ATOM   3923 C CD2 . LEU C 3 80  ? -3.833  -26.785 -37.057 1.00 33.54  ? 80  LEU C CD2 1 
ATOM   3924 N N   . GLN C 3 81  ? -5.618  -25.629 -41.963 1.00 21.25  ? 81  GLN C N   1 
ATOM   3925 C CA  . GLN C 3 81  ? -4.884  -25.802 -43.212 1.00 25.27  ? 81  GLN C CA  1 
ATOM   3926 C C   . GLN C 3 81  ? -3.409  -25.516 -42.956 1.00 37.48  ? 81  GLN C C   1 
ATOM   3927 O O   . GLN C 3 81  ? -3.031  -24.375 -42.671 1.00 51.12  ? 81  GLN C O   1 
ATOM   3928 C CB  . GLN C 3 81  ? -5.440  -24.881 -44.294 1.00 34.97  ? 81  GLN C CB  1 
ATOM   3929 C CG  . GLN C 3 81  ? -4.675  -24.931 -45.603 1.00 43.00  ? 81  GLN C CG  1 
ATOM   3930 C CD  . GLN C 3 81  ? -4.917  -26.215 -46.369 1.00 41.19  ? 81  GLN C CD  1 
ATOM   3931 O OE1 . GLN C 3 81  ? -6.059  -26.644 -46.537 1.00 40.45  ? 81  GLN C OE1 1 
ATOM   3932 N NE2 . GLN C 3 81  ? -3.840  -26.839 -46.835 1.00 35.21  ? 81  GLN C NE2 1 
ATOM   3933 N N   . MET C 3 82  ? -2.576  -26.548 -43.065 1.00 36.14  ? 82  MET C N   1 
ATOM   3934 C CA  . MET C 3 82  ? -1.146  -26.439 -42.800 1.00 41.73  ? 82  MET C CA  1 
ATOM   3935 C C   . MET C 3 82  ? -0.401  -26.445 -44.130 1.00 44.88  ? 82  MET C C   1 
ATOM   3936 O O   . MET C 3 82  ? -0.402  -27.451 -44.846 1.00 53.18  ? 82  MET C O   1 
ATOM   3937 C CB  . MET C 3 82  ? -0.682  -27.579 -41.896 1.00 28.39  ? 82  MET C CB  1 
ATOM   3938 C CG  . MET C 3 82  ? -1.428  -27.644 -40.574 1.00 36.52  ? 82  MET C CG  1 
ATOM   3939 S SD  . MET C 3 82  ? -0.714  -28.812 -39.402 1.00 51.89  ? 82  MET C SD  1 
ATOM   3940 C CE  . MET C 3 82  ? -1.402  -30.354 -39.990 1.00 46.77  ? 82  MET C CE  1 
ATOM   3941 N N   . ASN C 3 83  A 0.236   -25.323 -44.457 1.00 42.20  ? 82  ASN C N   1 
ATOM   3942 C CA  . ASN C 3 83  A 0.998   -25.176 -45.687 1.00 44.36  ? 82  ASN C CA  1 
ATOM   3943 C C   . ASN C 3 83  A 2.441   -24.819 -45.356 1.00 42.62  ? 82  ASN C C   1 
ATOM   3944 O O   . ASN C 3 83  A 2.740   -24.303 -44.276 1.00 51.08  ? 82  ASN C O   1 
ATOM   3945 C CB  . ASN C 3 83  A 0.386   -24.104 -46.599 1.00 40.37  ? 82  ASN C CB  1 
ATOM   3946 C CG  . ASN C 3 83  A -1.037  -24.427 -47.006 1.00 43.67  ? 82  ASN C CG  1 
ATOM   3947 O OD1 . ASN C 3 83  A -1.464  -25.581 -46.953 1.00 50.32  ? 82  ASN C OD1 1 
ATOM   3948 N ND2 . ASN C 3 83  A -1.780  -23.407 -47.421 1.00 37.51  ? 82  ASN C ND2 1 
ATOM   3949 N N   . SER C 3 84  B 3.334   -25.101 -46.306 1.00 48.22  ? 82  SER C N   1 
ATOM   3950 C CA  . SER C 3 84  B 4.774   -24.905 -46.125 1.00 53.17  ? 82  SER C CA  1 
ATOM   3951 C C   . SER C 3 84  B 5.260   -25.601 -44.855 1.00 45.23  ? 82  SER C C   1 
ATOM   3952 O O   . SER C 3 84  B 5.975   -25.029 -44.029 1.00 42.08  ? 82  SER C O   1 
ATOM   3953 C CB  . SER C 3 84  B 5.131   -23.417 -46.111 1.00 44.26  ? 82  SER C CB  1 
ATOM   3954 O OG  . SER C 3 84  B 4.906   -22.826 -47.380 1.00 41.54  ? 82  SER C OG  1 
ATOM   3955 N N   . LEU C 3 85  C 4.854   -26.859 -44.706 1.00 37.25  ? 82  LEU C N   1 
ATOM   3956 C CA  . LEU C 3 85  C 5.130   -27.607 -43.489 1.00 46.09  ? 82  LEU C CA  1 
ATOM   3957 C C   . LEU C 3 85  C 6.622   -27.873 -43.326 1.00 50.32  ? 82  LEU C C   1 
ATOM   3958 O O   . LEU C 3 85  C 7.377   -27.957 -44.298 1.00 50.72  ? 82  LEU C O   1 
ATOM   3959 C CB  . LEU C 3 85  C 4.356   -28.925 -43.493 1.00 51.52  ? 82  LEU C CB  1 
ATOM   3960 C CG  . LEU C 3 85  C 2.907   -28.805 -43.021 1.00 51.03  ? 82  LEU C CG  1 
ATOM   3961 C CD1 . LEU C 3 85  C 2.079   -29.988 -43.485 1.00 51.99  ? 82  LEU C CD1 1 
ATOM   3962 C CD2 . LEU C 3 85  C 2.863   -28.685 -41.506 1.00 42.51  ? 82  LEU C CD2 1 
ATOM   3963 N N   . ARG C 3 86  ? 7.041   -28.001 -42.070 1.00 50.94  ? 83  ARG C N   1 
ATOM   3964 C CA  . ARG C 3 86  ? 8.431   -28.217 -41.705 1.00 40.08  ? 83  ARG C CA  1 
ATOM   3965 C C   . ARG C 3 86  ? 8.526   -29.426 -40.787 1.00 42.73  ? 83  ARG C C   1 
ATOM   3966 O O   . ARG C 3 86  ? 7.528   -29.898 -40.235 1.00 55.36  ? 83  ARG C O   1 
ATOM   3967 C CB  . ARG C 3 86  ? 9.027   -26.983 -41.015 1.00 50.53  ? 83  ARG C CB  1 
ATOM   3968 C CG  . ARG C 3 86  ? 8.847   -25.688 -41.787 1.00 47.59  ? 83  ARG C CG  1 
ATOM   3969 C CD  . ARG C 3 86  ? 9.262   -24.491 -40.948 1.00 49.33  ? 83  ARG C CD  1 
ATOM   3970 N NE  . ARG C 3 86  ? 8.968   -23.228 -41.613 1.00 51.19  ? 83  ARG C NE  1 
ATOM   3971 C CZ  . ARG C 3 86  ? 9.123   -22.035 -41.057 1.00 55.28  ? 83  ARG C CZ  1 
ATOM   3972 N NH1 . ARG C 3 86  ? 9.564   -21.902 -39.816 1.00 53.56  ? 83  ARG C NH1 1 
ATOM   3973 N NH2 . ARG C 3 86  ? 8.828   -20.946 -41.762 1.00 52.59  ? 83  ARG C NH2 1 
ATOM   3974 N N   . VAL C 3 87  ? 9.753   -29.924 -40.622 1.00 43.57  ? 84  VAL C N   1 
ATOM   3975 C CA  . VAL C 3 87  ? 9.973   -31.099 -39.785 1.00 60.22  ? 84  VAL C CA  1 
ATOM   3976 C C   . VAL C 3 87  ? 9.647   -30.796 -38.327 1.00 58.84  ? 84  VAL C C   1 
ATOM   3977 O O   . VAL C 3 87  ? 9.174   -31.674 -37.595 1.00 45.38  ? 84  VAL C O   1 
ATOM   3978 C CB  . VAL C 3 87  ? 11.416  -31.608 -39.952 1.00 50.07  ? 84  VAL C CB  1 
ATOM   3979 C CG1 . VAL C 3 87  ? 11.569  -32.988 -39.330 1.00 50.56  ? 84  VAL C CG1 1 
ATOM   3980 C CG2 . VAL C 3 87  ? 11.799  -31.635 -41.424 1.00 23.04  ? 84  VAL C CG2 1 
ATOM   3981 N N   . GLU C 3 88  ? 9.893   -29.561 -37.878 1.00 65.13  ? 85  GLU C N   1 
ATOM   3982 C CA  . GLU C 3 88  ? 9.583   -29.192 -36.501 1.00 53.72  ? 85  GLU C CA  1 
ATOM   3983 C C   . GLU C 3 88  ? 8.085   -29.194 -36.222 1.00 54.28  ? 85  GLU C C   1 
ATOM   3984 O O   . GLU C 3 88  ? 7.684   -29.308 -35.059 1.00 53.23  ? 85  GLU C O   1 
ATOM   3985 C CB  . GLU C 3 88  ? 10.166  -27.815 -36.177 1.00 42.07  ? 85  GLU C CB  1 
ATOM   3986 C CG  . GLU C 3 88  ? 11.604  -27.634 -36.621 1.00 67.39  ? 85  GLU C CG  1 
ATOM   3987 C CD  . GLU C 3 88  ? 11.723  -26.799 -37.879 1.00 77.31  ? 85  GLU C CD  1 
ATOM   3988 O OE1 . GLU C 3 88  ? 11.721  -25.555 -37.767 1.00 83.67  ? 85  GLU C OE1 1 
ATOM   3989 O OE2 . GLU C 3 88  ? 11.812  -27.385 -38.979 1.00 77.35  ? 85  GLU C OE2 1 
ATOM   3990 N N   . ASP C 3 89  ? 7.252   -29.075 -37.258 1.00 48.98  ? 86  ASP C N   1 
ATOM   3991 C CA  . ASP C 3 89  ? 5.806   -29.103 -37.076 1.00 39.09  ? 86  ASP C CA  1 
ATOM   3992 C C   . ASP C 3 89  ? 5.281   -30.490 -36.727 1.00 49.45  ? 86  ASP C C   1 
ATOM   3993 O O   . ASP C 3 89  ? 4.095   -30.617 -36.402 1.00 53.01  ? 86  ASP C O   1 
ATOM   3994 C CB  . ASP C 3 89  ? 5.110   -28.586 -38.336 1.00 38.35  ? 86  ASP C CB  1 
ATOM   3995 C CG  . ASP C 3 89  ? 5.477   -27.148 -38.653 1.00 51.67  ? 86  ASP C CG  1 
ATOM   3996 O OD1 . ASP C 3 89  ? 5.775   -26.385 -37.709 1.00 56.79  ? 86  ASP C OD1 1 
ATOM   3997 O OD2 . ASP C 3 89  ? 5.465   -26.780 -39.846 1.00 42.66  ? 86  ASP C OD2 1 
ATOM   3998 N N   . THR C 3 90  ? 6.123   -31.522 -36.798 1.00 46.10  ? 87  THR C N   1 
ATOM   3999 C CA  . THR C 3 90  ? 5.725   -32.882 -36.452 1.00 47.67  ? 87  THR C CA  1 
ATOM   4000 C C   . THR C 3 90  ? 5.228   -32.954 -35.015 1.00 49.22  ? 87  THR C C   1 
ATOM   4001 O O   . THR C 3 90  ? 6.007   -32.773 -34.073 1.00 59.98  ? 87  THR C O   1 
ATOM   4002 C CB  . THR C 3 90  ? 6.893   -33.850 -36.649 1.00 38.02  ? 87  THR C CB  1 
ATOM   4003 O OG1 . THR C 3 90  ? 7.340   -33.797 -38.010 1.00 49.25  ? 87  THR C OG1 1 
ATOM   4004 C CG2 . THR C 3 90  ? 6.470   -35.273 -36.310 1.00 26.87  ? 87  THR C CG2 1 
ATOM   4005 N N   . ALA C 3 91  ? 3.936   -33.222 -34.839 1.00 37.95  ? 88  ALA C N   1 
ATOM   4006 C CA  . ALA C 3 91  ? 3.335   -33.262 -33.514 1.00 43.75  ? 88  ALA C CA  1 
ATOM   4007 C C   . ALA C 3 91  ? 1.982   -33.951 -33.607 1.00 44.62  ? 88  ALA C C   1 
ATOM   4008 O O   . ALA C 3 91  ? 1.428   -34.138 -34.693 1.00 44.11  ? 88  ALA C O   1 
ATOM   4009 C CB  . ALA C 3 91  ? 3.183   -31.855 -32.926 1.00 55.69  ? 88  ALA C CB  1 
ATOM   4010 N N   . VAL C 3 92  ? 1.458   -34.331 -32.446 1.00 47.05  ? 89  VAL C N   1 
ATOM   4011 C CA  . VAL C 3 92  ? 0.080   -34.790 -32.328 1.00 41.49  ? 89  VAL C CA  1 
ATOM   4012 C C   . VAL C 3 92  ? -0.784  -33.553 -32.117 1.00 41.11  ? 89  VAL C C   1 
ATOM   4013 O O   . VAL C 3 92  ? -0.686  -32.884 -31.085 1.00 44.31  ? 89  VAL C O   1 
ATOM   4014 C CB  . VAL C 3 92  ? -0.091  -35.793 -31.181 1.00 39.87  ? 89  VAL C CB  1 
ATOM   4015 C CG1 . VAL C 3 92  ? -1.566  -36.071 -30.936 1.00 38.24  ? 89  VAL C CG1 1 
ATOM   4016 C CG2 . VAL C 3 92  ? 0.649   -37.083 -31.491 1.00 32.55  ? 89  VAL C CG2 1 
ATOM   4017 N N   . TYR C 3 93  ? -1.621  -33.241 -33.100 1.00 43.31  ? 90  TYR C N   1 
ATOM   4018 C CA  . TYR C 3 93  ? -2.442  -32.039 -33.061 1.00 37.89  ? 90  TYR C CA  1 
ATOM   4019 C C   . TYR C 3 93  ? -3.786  -32.349 -32.418 1.00 39.29  ? 90  TYR C C   1 
ATOM   4020 O O   . TYR C 3 93  ? -4.447  -33.327 -32.782 1.00 34.72  ? 90  TYR C O   1 
ATOM   4021 C CB  . TYR C 3 93  ? -2.638  -31.478 -34.468 1.00 31.57  ? 90  TYR C CB  1 
ATOM   4022 C CG  . TYR C 3 93  ? -1.422  -30.769 -35.017 1.00 40.47  ? 90  TYR C CG  1 
ATOM   4023 C CD1 . TYR C 3 93  ? -0.291  -31.479 -35.400 1.00 47.02  ? 90  TYR C CD1 1 
ATOM   4024 C CD2 . TYR C 3 93  ? -1.407  -29.388 -35.158 1.00 35.39  ? 90  TYR C CD2 1 
ATOM   4025 C CE1 . TYR C 3 93  ? 0.823   -30.833 -35.902 1.00 42.00  ? 90  TYR C CE1 1 
ATOM   4026 C CE2 . TYR C 3 93  ? -0.298  -28.733 -35.660 1.00 33.67  ? 90  TYR C CE2 1 
ATOM   4027 C CZ  . TYR C 3 93  ? 0.814   -29.461 -36.030 1.00 45.68  ? 90  TYR C CZ  1 
ATOM   4028 O OH  . TYR C 3 93  ? 1.920   -28.815 -36.530 1.00 51.73  ? 90  TYR C OH  1 
ATOM   4029 N N   . TYR C 3 94  ? -4.182  -31.517 -31.459 1.00 33.29  ? 91  TYR C N   1 
ATOM   4030 C CA  . TYR C 3 94  ? -5.440  -31.674 -30.749 1.00 33.54  ? 91  TYR C CA  1 
ATOM   4031 C C   . TYR C 3 94  ? -6.424  -30.592 -31.169 1.00 28.20  ? 91  TYR C C   1 
ATOM   4032 O O   . TYR C 3 94  ? -6.036  -29.483 -31.547 1.00 27.66  ? 91  TYR C O   1 
ATOM   4033 C CB  . TYR C 3 94  ? -5.238  -31.610 -29.232 1.00 36.31  ? 91  TYR C CB  1 
ATOM   4034 C CG  . TYR C 3 94  ? -4.459  -32.767 -28.654 1.00 36.77  ? 91  TYR C CG  1 
ATOM   4035 C CD1 . TYR C 3 94  ? -5.101  -33.933 -28.262 1.00 42.77  ? 91  TYR C CD1 1 
ATOM   4036 C CD2 . TYR C 3 94  ? -3.083  -32.688 -28.487 1.00 41.24  ? 91  TYR C CD2 1 
ATOM   4037 C CE1 . TYR C 3 94  ? -4.395  -34.991 -27.727 1.00 49.37  ? 91  TYR C CE1 1 
ATOM   4038 C CE2 . TYR C 3 94  ? -2.367  -33.741 -27.953 1.00 41.59  ? 91  TYR C CE2 1 
ATOM   4039 C CZ  . TYR C 3 94  ? -3.029  -34.890 -27.575 1.00 41.22  ? 91  TYR C CZ  1 
ATOM   4040 O OH  . TYR C 3 94  ? -2.322  -35.943 -27.041 1.00 45.65  ? 91  TYR C OH  1 
ATOM   4041 N N   . CYS C 3 95  ? -7.704  -30.934 -31.098 1.00 40.21  ? 92  CYS C N   1 
ATOM   4042 C CA  . CYS C 3 95  ? -8.796  -29.997 -31.313 1.00 37.57  ? 92  CYS C CA  1 
ATOM   4043 C C   . CYS C 3 95  ? -9.476  -29.746 -29.976 1.00 39.55  ? 92  CYS C C   1 
ATOM   4044 O O   . CYS C 3 95  ? -9.881  -30.695 -29.296 1.00 42.13  ? 92  CYS C O   1 
ATOM   4045 C CB  . CYS C 3 95  ? -9.793  -30.551 -32.330 1.00 35.10  ? 92  CYS C CB  1 
ATOM   4046 S SG  . CYS C 3 95  ? -11.181 -29.476 -32.712 1.00 82.52  ? 92  CYS C SG  1 
ATOM   4047 N N   . ALA C 3 96  ? -9.591  -28.477 -29.594 1.00 27.20  ? 93  ALA C N   1 
ATOM   4048 C CA  . ALA C 3 96  ? -10.083 -28.124 -28.271 1.00 35.05  ? 93  ALA C CA  1 
ATOM   4049 C C   . ALA C 3 96  ? -11.109 -27.008 -28.368 1.00 39.56  ? 93  ALA C C   1 
ATOM   4050 O O   . ALA C 3 96  ? -10.863 -25.986 -29.018 1.00 37.15  ? 93  ALA C O   1 
ATOM   4051 C CB  . ALA C 3 96  ? -8.933  -27.701 -27.352 1.00 40.18  ? 93  ALA C CB  1 
ATOM   4052 N N   . ARG C 3 97  ? -12.253 -27.207 -27.719 1.00 42.46  ? 94  ARG C N   1 
ATOM   4053 C CA  . ARG C 3 97  ? -13.200 -26.119 -27.525 1.00 44.03  ? 94  ARG C CA  1 
ATOM   4054 C C   . ARG C 3 97  ? -12.629 -25.140 -26.508 1.00 46.64  ? 94  ARG C C   1 
ATOM   4055 O O   . ARG C 3 97  ? -12.216 -25.537 -25.414 1.00 41.58  ? 94  ARG C O   1 
ATOM   4056 C CB  . ARG C 3 97  ? -14.546 -26.661 -27.050 1.00 45.90  ? 94  ARG C CB  1 
ATOM   4057 C CG  . ARG C 3 97  ? -15.602 -25.597 -26.800 1.00 40.40  ? 94  ARG C CG  1 
ATOM   4058 C CD  . ARG C 3 97  ? -16.180 -25.726 -25.400 1.00 53.97  ? 94  ARG C CD  1 
ATOM   4059 N NE  . ARG C 3 97  ? -17.462 -25.045 -25.267 1.00 41.22  ? 94  ARG C NE  1 
ATOM   4060 C CZ  . ARG C 3 97  ? -18.637 -25.627 -25.462 1.00 46.57  ? 94  ARG C CZ  1 
ATOM   4061 N NH1 . ARG C 3 97  ? -18.729 -26.900 -25.807 1.00 46.49  ? 94  ARG C NH1 1 
ATOM   4062 N NH2 . ARG C 3 97  ? -19.748 -24.913 -25.306 1.00 61.80  ? 94  ARG C NH2 1 
ATOM   4063 N N   . ASP C 3 98  ? -12.605 -23.862 -26.867 1.00 48.10  ? 95  ASP C N   1 
ATOM   4064 C CA  . ASP C 3 98  ? -11.956 -22.830 -26.071 1.00 41.82  ? 95  ASP C CA  1 
ATOM   4065 C C   . ASP C 3 98  ? -13.016 -21.996 -25.368 1.00 48.67  ? 95  ASP C C   1 
ATOM   4066 O O   . ASP C 3 98  ? -13.967 -21.531 -26.005 1.00 62.92  ? 95  ASP C O   1 
ATOM   4067 C CB  . ASP C 3 98  ? -11.074 -21.946 -26.957 1.00 41.23  ? 95  ASP C CB  1 
ATOM   4068 C CG  . ASP C 3 98  ? -10.074 -21.129 -26.163 1.00 56.42  ? 95  ASP C CG  1 
ATOM   4069 O OD1 . ASP C 3 98  ? -10.155 -21.123 -24.917 1.00 64.92  ? 95  ASP C OD1 1 
ATOM   4070 O OD2 . ASP C 3 98  ? -9.199  -20.498 -26.793 1.00 57.07  ? 95  ASP C OD2 1 
ATOM   4071 N N   . PHE C 3 99  ? -12.859 -21.814 -24.057 1.00 41.43  ? 96  PHE C N   1 
ATOM   4072 C CA  . PHE C 3 99  ? -13.806 -21.017 -23.278 1.00 32.97  ? 96  PHE C CA  1 
ATOM   4073 C C   . PHE C 3 99  ? -13.320 -19.575 -23.254 1.00 32.61  ? 96  PHE C C   1 
ATOM   4074 O O   . PHE C 3 99  ? -12.515 -19.180 -22.411 1.00 32.11  ? 96  PHE C O   1 
ATOM   4075 C CB  . PHE C 3 99  ? -13.971 -21.572 -21.869 1.00 34.86  ? 96  PHE C CB  1 
ATOM   4076 C CG  . PHE C 3 99  ? -15.038 -20.873 -21.074 1.00 40.24  ? 96  PHE C CG  1 
ATOM   4077 C CD1 . PHE C 3 99  ? -16.362 -21.266 -21.176 1.00 49.61  ? 96  PHE C CD1 1 
ATOM   4078 C CD2 . PHE C 3 99  ? -14.721 -19.814 -20.240 1.00 41.26  ? 96  PHE C CD2 1 
ATOM   4079 C CE1 . PHE C 3 99  ? -17.348 -20.622 -20.455 1.00 47.81  ? 96  PHE C CE1 1 
ATOM   4080 C CE2 . PHE C 3 99  ? -15.703 -19.166 -19.517 1.00 35.21  ? 96  PHE C CE2 1 
ATOM   4081 C CZ  . PHE C 3 99  ? -17.018 -19.571 -19.624 1.00 40.35  ? 96  PHE C CZ  1 
ATOM   4082 N N   . GLY C 3 100 ? -13.821 -18.781 -24.194 1.00 53.59  ? 97  GLY C N   1 
ATOM   4083 C CA  . GLY C 3 100 ? -13.508 -17.361 -24.222 1.00 48.04  ? 97  GLY C CA  1 
ATOM   4084 C C   . GLY C 3 100 ? -12.035 -17.055 -24.375 1.00 54.17  ? 97  GLY C C   1 
ATOM   4085 O O   . GLY C 3 100 ? -11.532 -16.117 -23.743 1.00 65.30  ? 97  GLY C O   1 
ATOM   4086 N N   . ASP C 3 101 ? -11.326 -17.837 -25.194 1.00 47.99  ? 98  ASP C N   1 
ATOM   4087 C CA  . ASP C 3 101 ? -9.904  -17.621 -25.464 1.00 56.30  ? 98  ASP C CA  1 
ATOM   4088 C C   . ASP C 3 101 ? -9.066  -17.723 -24.189 1.00 50.48  ? 98  ASP C C   1 
ATOM   4089 O O   . ASP C 3 101 ? -7.993  -17.122 -24.087 1.00 53.75  ? 98  ASP C O   1 
ATOM   4090 C CB  . ASP C 3 101 ? -9.678  -16.272 -26.161 1.00 45.02  ? 98  ASP C CB  1 
ATOM   4091 C CG  . ASP C 3 101 ? -8.340  -16.186 -26.872 1.00 54.18  ? 98  ASP C CG  1 
ATOM   4092 O OD1 . ASP C 3 101 ? -7.617  -17.201 -26.920 1.00 64.91  ? 98  ASP C OD1 1 
ATOM   4093 O OD2 . ASP C 3 101 ? -8.014  -15.095 -27.385 1.00 50.61  ? 98  ASP C OD2 1 
ATOM   4094 N N   . PHE C 3 102 ? -9.547  -18.481 -23.202 1.00 40.52  ? 99  PHE C N   1 
ATOM   4095 C CA  . PHE C 3 102 ? -8.845  -18.638 -21.933 1.00 44.41  ? 99  PHE C CA  1 
ATOM   4096 C C   . PHE C 3 102 ? -8.354  -20.062 -21.713 1.00 40.18  ? 99  PHE C C   1 
ATOM   4097 O O   . PHE C 3 102 ? -7.149  -20.291 -21.582 1.00 45.38  ? 99  PHE C O   1 
ATOM   4098 C CB  . PHE C 3 102 ? -9.754  -18.221 -20.767 1.00 45.25  ? 99  PHE C CB  1 
ATOM   4099 C CG  . PHE C 3 102 ? -10.101 -16.760 -20.750 1.00 40.66  ? 99  PHE C CG  1 
ATOM   4100 C CD1 . PHE C 3 102 ? -9.347  -15.841 -21.460 1.00 50.25  ? 99  PHE C CD1 1 
ATOM   4101 C CD2 . PHE C 3 102 ? -11.182 -16.306 -20.013 1.00 39.23  ? 99  PHE C CD2 1 
ATOM   4102 C CE1 . PHE C 3 102 ? -9.670  -14.498 -21.442 1.00 58.32  ? 99  PHE C CE1 1 
ATOM   4103 C CE2 . PHE C 3 102 ? -11.509 -14.965 -19.988 1.00 47.73  ? 99  PHE C CE2 1 
ATOM   4104 C CZ  . PHE C 3 102 ? -10.751 -14.060 -20.704 1.00 55.20  ? 99  PHE C CZ  1 
ATOM   4105 N N   . TYR C 3 103 ? -9.257  -21.038 -21.697 1.00 43.77  ? 100 TYR C N   1 
ATOM   4106 C CA  . TYR C 3 103 ? -8.880  -22.405 -21.374 1.00 41.81  ? 100 TYR C CA  1 
ATOM   4107 C C   . TYR C 3 103 ? -9.759  -23.364 -22.159 1.00 46.88  ? 100 TYR C C   1 
ATOM   4108 O O   . TYR C 3 103 ? -10.810 -22.989 -22.687 1.00 43.30  ? 100 TYR C O   1 
ATOM   4109 C CB  . TYR C 3 103 ? -8.978  -22.679 -19.867 1.00 34.63  ? 100 TYR C CB  1 
ATOM   4110 C CG  . TYR C 3 103 ? -10.361 -22.497 -19.281 1.00 47.57  ? 100 TYR C CG  1 
ATOM   4111 C CD1 . TYR C 3 103 ? -10.787 -21.254 -18.831 1.00 40.90  ? 100 TYR C CD1 1 
ATOM   4112 C CD2 . TYR C 3 103 ? -11.234 -23.571 -19.163 1.00 46.23  ? 100 TYR C CD2 1 
ATOM   4113 C CE1 . TYR C 3 103 ? -12.047 -21.083 -18.290 1.00 40.08  ? 100 TYR C CE1 1 
ATOM   4114 C CE2 . TYR C 3 103 ? -12.497 -23.410 -18.624 1.00 45.94  ? 100 TYR C CE2 1 
ATOM   4115 C CZ  . TYR C 3 103 ? -12.898 -22.164 -18.189 1.00 48.80  ? 100 TYR C CZ  1 
ATOM   4116 O OH  . TYR C 3 103 ? -14.153 -21.997 -17.651 1.00 37.85  ? 100 TYR C OH  1 
ATOM   4117 N N   . PHE C 3 104 A -9.310  -24.613 -22.230 1.00 45.02  ? 100 PHE C N   1 
ATOM   4118 C CA  . PHE C 3 104 A -9.906  -25.627 -23.091 1.00 40.30  ? 100 PHE C CA  1 
ATOM   4119 C C   . PHE C 3 104 A -10.636 -26.646 -22.225 1.00 35.69  ? 100 PHE C C   1 
ATOM   4120 O O   . PHE C 3 104 A -10.002 -27.491 -21.584 1.00 33.63  ? 100 PHE C O   1 
ATOM   4121 C CB  . PHE C 3 104 A -8.828  -26.286 -23.945 1.00 39.36  ? 100 PHE C CB  1 
ATOM   4122 C CG  . PHE C 3 104 A -7.789  -25.322 -24.447 1.00 36.40  ? 100 PHE C CG  1 
ATOM   4123 C CD1 . PHE C 3 104 A -8.019  -24.566 -25.584 1.00 44.50  ? 100 PHE C CD1 1 
ATOM   4124 C CD2 . PHE C 3 104 A -6.588  -25.161 -23.774 1.00 36.13  ? 100 PHE C CD2 1 
ATOM   4125 C CE1 . PHE C 3 104 A -7.070  -23.673 -26.044 1.00 45.07  ? 100 PHE C CE1 1 
ATOM   4126 C CE2 . PHE C 3 104 A -5.635  -24.269 -24.228 1.00 35.67  ? 100 PHE C CE2 1 
ATOM   4127 C CZ  . PHE C 3 104 A -5.876  -23.524 -25.365 1.00 30.98  ? 100 PHE C CZ  1 
ATOM   4128 N N   . ASP C 3 105 ? -11.967 -26.565 -22.210 1.00 42.42  ? 101 ASP C N   1 
ATOM   4129 C CA  . ASP C 3 105 ? -12.788 -27.440 -21.385 1.00 45.68  ? 101 ASP C CA  1 
ATOM   4130 C C   . ASP C 3 105 ? -13.173 -28.742 -22.075 1.00 34.23  ? 101 ASP C C   1 
ATOM   4131 O O   . ASP C 3 105 ? -13.728 -29.630 -21.418 1.00 40.63  ? 101 ASP C O   1 
ATOM   4132 C CB  . ASP C 3 105 ? -14.059 -26.705 -20.936 1.00 55.63  ? 101 ASP C CB  1 
ATOM   4133 C CG  . ASP C 3 105 ? -14.730 -25.947 -22.068 1.00 57.12  ? 101 ASP C CG  1 
ATOM   4134 O OD1 . ASP C 3 105 ? -14.013 -25.447 -22.959 1.00 60.97  ? 101 ASP C OD1 1 
ATOM   4135 O OD2 . ASP C 3 105 ? -15.976 -25.848 -22.064 1.00 58.47  ? 101 ASP C OD2 1 
ATOM   4136 N N   . TYR C 3 106 ? -12.898 -28.883 -23.370 1.00 32.87  ? 102 TYR C N   1 
ATOM   4137 C CA  . TYR C 3 106 ? -13.177 -30.120 -24.086 1.00 35.87  ? 102 TYR C CA  1 
ATOM   4138 C C   . TYR C 3 106 ? -12.113 -30.321 -25.154 1.00 34.90  ? 102 TYR C C   1 
ATOM   4139 O O   . TYR C 3 106 ? -11.756 -29.379 -25.867 1.00 26.40  ? 102 TYR C O   1 
ATOM   4140 C CB  . TYR C 3 106 ? -14.574 -30.107 -24.717 1.00 43.38  ? 102 TYR C CB  1 
ATOM   4141 C CG  . TYR C 3 106 ? -15.697 -30.269 -23.718 1.00 47.28  ? 102 TYR C CG  1 
ATOM   4142 C CD1 . TYR C 3 106 ? -16.066 -31.526 -23.257 1.00 45.89  ? 102 TYR C CD1 1 
ATOM   4143 C CD2 . TYR C 3 106 ? -16.389 -29.165 -23.235 1.00 49.25  ? 102 TYR C CD2 1 
ATOM   4144 C CE1 . TYR C 3 106 ? -17.091 -31.680 -22.343 1.00 60.08  ? 102 TYR C CE1 1 
ATOM   4145 C CE2 . TYR C 3 106 ? -17.417 -29.309 -22.320 1.00 42.28  ? 102 TYR C CE2 1 
ATOM   4146 C CZ  . TYR C 3 106 ? -17.764 -30.569 -21.878 1.00 53.89  ? 102 TYR C CZ  1 
ATOM   4147 O OH  . TYR C 3 106 ? -18.786 -30.719 -20.970 1.00 57.69  ? 102 TYR C OH  1 
ATOM   4148 N N   . TRP C 3 107 ? -11.623 -31.554 -25.265 1.00 40.96  ? 103 TRP C N   1 
ATOM   4149 C CA  . TRP C 3 107 ? -10.506 -31.885 -26.138 1.00 36.53  ? 103 TRP C CA  1 
ATOM   4150 C C   . TRP C 3 107 ? -10.880 -33.032 -27.064 1.00 38.27  ? 103 TRP C C   1 
ATOM   4151 O O   . TRP C 3 107 ? -11.608 -33.949 -26.671 1.00 31.05  ? 103 TRP C O   1 
ATOM   4152 C CB  . TRP C 3 107 ? -9.264  -32.271 -25.324 1.00 34.78  ? 103 TRP C CB  1 
ATOM   4153 C CG  . TRP C 3 107 ? -8.693  -31.151 -24.513 1.00 31.48  ? 103 TRP C CG  1 
ATOM   4154 C CD1 . TRP C 3 107 ? -9.259  -30.553 -23.425 1.00 36.13  ? 103 TRP C CD1 1 
ATOM   4155 C CD2 . TRP C 3 107 ? -7.432  -30.503 -24.716 1.00 30.15  ? 103 TRP C CD2 1 
ATOM   4156 N NE1 . TRP C 3 107 ? -8.433  -29.566 -22.944 1.00 33.79  ? 103 TRP C NE1 1 
ATOM   4157 C CE2 . TRP C 3 107 ? -7.304  -29.517 -23.718 1.00 29.83  ? 103 TRP C CE2 1 
ATOM   4158 C CE3 . TRP C 3 107 ? -6.400  -30.659 -25.646 1.00 31.87  ? 103 TRP C CE3 1 
ATOM   4159 C CZ2 . TRP C 3 107 ? -6.186  -28.691 -23.624 1.00 30.13  ? 103 TRP C CZ2 1 
ATOM   4160 C CZ3 . TRP C 3 107 ? -5.291  -29.839 -25.551 1.00 28.40  ? 103 TRP C CZ3 1 
ATOM   4161 C CH2 . TRP C 3 107 ? -5.193  -28.867 -24.548 1.00 28.29  ? 103 TRP C CH2 1 
ATOM   4162 N N   . GLY C 3 108 ? -10.378 -32.973 -28.300 1.00 35.63  ? 104 GLY C N   1 
ATOM   4163 C CA  . GLY C 3 108 ? -10.517 -34.083 -29.216 1.00 44.44  ? 104 GLY C CA  1 
ATOM   4164 C C   . GLY C 3 108 ? -9.479  -35.161 -28.968 1.00 47.38  ? 104 GLY C C   1 
ATOM   4165 O O   . GLY C 3 108 ? -8.482  -34.953 -28.279 1.00 42.69  ? 104 GLY C O   1 
ATOM   4166 N N   . GLN C 3 109 ? -9.715  -36.333 -29.564 1.00 48.37  ? 105 GLN C N   1 
ATOM   4167 C CA  . GLN C 3 109 ? -8.856  -37.483 -29.301 1.00 44.00  ? 105 GLN C CA  1 
ATOM   4168 C C   . GLN C 3 109 ? -7.442  -37.300 -29.843 1.00 41.32  ? 105 GLN C C   1 
ATOM   4169 O O   . GLN C 3 109 ? -6.528  -38.002 -29.398 1.00 43.14  ? 105 GLN C O   1 
ATOM   4170 C CB  . GLN C 3 109 ? -9.480  -38.756 -29.882 1.00 53.54  ? 105 GLN C CB  1 
ATOM   4171 C CG  . GLN C 3 109 ? -8.967  -39.158 -31.258 1.00 49.17  ? 105 GLN C CG  1 
ATOM   4172 C CD  . GLN C 3 109 ? -9.544  -38.315 -32.377 1.00 55.76  ? 105 GLN C CD  1 
ATOM   4173 O OE1 . GLN C 3 109 ? -10.438 -37.498 -32.160 1.00 64.09  ? 105 GLN C OE1 1 
ATOM   4174 N NE2 . GLN C 3 109 ? -9.035  -38.515 -33.587 1.00 58.95  ? 105 GLN C NE2 1 
ATOM   4175 N N   . GLY C 3 110 ? -7.240  -36.384 -30.775 1.00 54.48  ? 106 GLY C N   1 
ATOM   4176 C CA  . GLY C 3 110 ? -5.916  -36.098 -31.288 1.00 47.66  ? 106 GLY C CA  1 
ATOM   4177 C C   . GLY C 3 110 ? -5.614  -36.852 -32.570 1.00 44.16  ? 106 GLY C C   1 
ATOM   4178 O O   . GLY C 3 110 ? -6.071  -37.981 -32.788 1.00 46.21  ? 106 GLY C O   1 
ATOM   4179 N N   . THR C 3 111 ? -4.831  -36.218 -33.439 1.00 34.23  ? 107 THR C N   1 
ATOM   4180 C CA  . THR C 3 111 ? -4.394  -36.830 -34.684 1.00 39.11  ? 107 THR C CA  1 
ATOM   4181 C C   . THR C 3 111 ? -2.914  -36.537 -34.885 1.00 42.64  ? 107 THR C C   1 
ATOM   4182 O O   . THR C 3 111 ? -2.435  -35.451 -34.543 1.00 34.71  ? 107 THR C O   1 
ATOM   4183 C CB  . THR C 3 111 ? -5.218  -36.329 -35.883 1.00 39.35  ? 107 THR C CB  1 
ATOM   4184 O OG1 . THR C 3 111 ? -4.797  -37.002 -37.075 1.00 45.91  ? 107 THR C OG1 1 
ATOM   4185 C CG2 . THR C 3 111 ? -5.063  -34.824 -36.067 1.00 38.43  ? 107 THR C CG2 1 
ATOM   4186 N N   . LEU C 3 112 ? -2.191  -37.512 -35.429 1.00 47.51  ? 108 LEU C N   1 
ATOM   4187 C CA  . LEU C 3 112 ? -0.741  -37.443 -35.549 1.00 40.85  ? 108 LEU C CA  1 
ATOM   4188 C C   . LEU C 3 112 ? -0.347  -36.931 -36.929 1.00 40.91  ? 108 LEU C C   1 
ATOM   4189 O O   . LEU C 3 112 ? -0.847  -37.421 -37.946 1.00 44.28  ? 108 LEU C O   1 
ATOM   4190 C CB  . LEU C 3 112 ? -0.111  -38.813 -35.295 1.00 30.71  ? 108 LEU C CB  1 
ATOM   4191 C CG  . LEU C 3 112 ? 1.398   -38.947 -35.520 1.00 44.73  ? 108 LEU C CG  1 
ATOM   4192 C CD1 . LEU C 3 112 ? 2.169   -37.915 -34.713 1.00 42.17  ? 108 LEU C CD1 1 
ATOM   4193 C CD2 . LEU C 3 112 ? 1.863   -40.355 -35.175 1.00 38.28  ? 108 LEU C CD2 1 
ATOM   4194 N N   . VAL C 3 113 ? 0.551   -35.949 -36.955 1.00 34.89  ? 109 VAL C N   1 
ATOM   4195 C CA  . VAL C 3 113 ? 1.076   -35.376 -38.189 1.00 30.88  ? 109 VAL C CA  1 
ATOM   4196 C C   . VAL C 3 113 ? 2.578   -35.618 -38.219 1.00 48.75  ? 109 VAL C C   1 
ATOM   4197 O O   . VAL C 3 113 ? 3.297   -35.200 -37.303 1.00 58.83  ? 109 VAL C O   1 
ATOM   4198 C CB  . VAL C 3 113 ? 0.760   -33.877 -38.304 1.00 38.79  ? 109 VAL C CB  1 
ATOM   4199 C CG1 . VAL C 3 113 ? 1.608   -33.234 -39.392 1.00 35.00  ? 109 VAL C CG1 1 
ATOM   4200 C CG2 . VAL C 3 113 ? -0.718  -33.673 -38.586 1.00 48.37  ? 109 VAL C CG2 1 
ATOM   4201 N N   . THR C 3 114 ? 3.049   -36.287 -39.269 1.00 64.87  ? 110 THR C N   1 
ATOM   4202 C CA  . THR C 3 114 ? 4.464   -36.579 -39.460 1.00 47.01  ? 110 THR C CA  1 
ATOM   4203 C C   . THR C 3 114 ? 4.946   -35.872 -40.717 1.00 45.38  ? 110 THR C C   1 
ATOM   4204 O O   . THR C 3 114 ? 4.357   -36.035 -41.790 1.00 53.40  ? 110 THR C O   1 
ATOM   4205 C CB  . THR C 3 114 ? 4.705   -38.088 -39.571 1.00 42.47  ? 110 THR C CB  1 
ATOM   4206 O OG1 . THR C 3 114 ? 4.088   -38.755 -38.464 1.00 43.22  ? 110 THR C OG1 1 
ATOM   4207 C CG2 . THR C 3 114 ? 6.199   -38.392 -39.573 1.00 40.80  ? 110 THR C CG2 1 
ATOM   4208 N N   . VAL C 3 115 ? 6.008   -35.084 -40.582 1.00 44.31  ? 111 VAL C N   1 
ATOM   4209 C CA  . VAL C 3 115 ? 6.593   -34.344 -41.698 1.00 41.96  ? 111 VAL C CA  1 
ATOM   4210 C C   . VAL C 3 115 ? 8.022   -34.828 -41.879 1.00 61.30  ? 111 VAL C C   1 
ATOM   4211 O O   . VAL C 3 115 ? 8.904   -34.501 -41.076 1.00 64.32  ? 111 VAL C O   1 
ATOM   4212 C CB  . VAL C 3 115 ? 6.550   -32.831 -41.481 1.00 43.05  ? 111 VAL C CB  1 
ATOM   4213 C CG1 . VAL C 3 115 ? 7.345   -32.120 -42.567 1.00 48.22  ? 111 VAL C CG1 1 
ATOM   4214 C CG2 . VAL C 3 115 ? 5.114   -32.345 -41.482 1.00 62.83  ? 111 VAL C CG2 1 
ATOM   4215 N N   . SER C 3 116 ? 8.248   -35.611 -42.931 1.00 74.72  ? 112 SER C N   1 
ATOM   4216 C CA  . SER C 3 116 ? 9.577   -36.098 -43.256 1.00 63.82  ? 112 SER C CA  1 
ATOM   4217 C C   . SER C 3 116 ? 9.658   -36.337 -44.753 1.00 59.51  ? 112 SER C C   1 
ATOM   4218 O O   . SER C 3 116 ? 8.647   -36.604 -45.409 1.00 66.04  ? 112 SER C O   1 
ATOM   4219 C CB  . SER C 3 116 ? 9.907   -37.387 -42.494 1.00 51.67  ? 112 SER C CB  1 
ATOM   4220 O OG  . SER C 3 116 ? 11.152  -37.921 -42.906 1.00 59.06  ? 112 SER C OG  1 
ATOM   4221 N N   . SER C 3 117 ? 10.875  -36.233 -45.286 1.00 59.59  ? 113 SER C N   1 
ATOM   4222 C CA  . SER C 3 117 ? 11.139  -36.594 -46.670 1.00 61.01  ? 113 SER C CA  1 
ATOM   4223 C C   . SER C 3 117 ? 11.282  -38.099 -46.851 1.00 64.43  ? 113 SER C C   1 
ATOM   4224 O O   . SER C 3 117 ? 11.579  -38.551 -47.963 1.00 70.26  ? 113 SER C O   1 
ATOM   4225 C CB  . SER C 3 117 ? 12.399  -35.874 -47.177 1.00 46.31  ? 113 SER C CB  1 
ATOM   4226 O OG  . SER C 3 117 ? 13.502  -36.085 -46.316 1.00 71.07  ? 113 SER C OG  1 
ATOM   4227 N N   . ALA C 3 118 ? 11.068  -38.879 -45.792 1.00 56.99  ? 114 ALA C N   1 
ATOM   4228 C CA  . ALA C 3 118 ? 11.099  -40.329 -45.891 1.00 48.76  ? 114 ALA C CA  1 
ATOM   4229 C C   . ALA C 3 118 ? 9.851   -40.830 -46.615 1.00 60.95  ? 114 ALA C C   1 
ATOM   4230 O O   . ALA C 3 118 ? 8.968   -40.059 -46.998 1.00 69.59  ? 114 ALA C O   1 
ATOM   4231 C CB  . ALA C 3 118 ? 11.222  -40.955 -44.504 1.00 38.00  ? 114 ALA C CB  1 
ATOM   4232 N N   . SER C 3 119 ? 9.770   -42.147 -46.795 1.00 52.96  ? 115 SER C N   1 
ATOM   4233 C CA  . SER C 3 119 ? 8.706   -42.755 -47.582 1.00 49.22  ? 115 SER C CA  1 
ATOM   4234 C C   . SER C 3 119 ? 8.045   -43.875 -46.796 1.00 44.57  ? 115 SER C C   1 
ATOM   4235 O O   . SER C 3 119 ? 8.707   -44.586 -46.034 1.00 46.98  ? 115 SER C O   1 
ATOM   4236 C CB  . SER C 3 119 ? 9.240   -43.293 -48.916 1.00 50.41  ? 115 SER C CB  1 
ATOM   4237 O OG  . SER C 3 119 ? 9.617   -42.229 -49.773 1.00 69.23  ? 115 SER C OG  1 
ATOM   4238 N N   . THR C 3 120 ? 6.736   -44.024 -46.992 1.00 35.14  ? 116 THR C N   1 
ATOM   4239 C CA  . THR C 3 120 ? 5.965   -45.018 -46.257 1.00 48.17  ? 116 THR C CA  1 
ATOM   4240 C C   . THR C 3 120 ? 6.427   -46.426 -46.608 1.00 46.15  ? 116 THR C C   1 
ATOM   4241 O O   . THR C 3 120 ? 6.590   -46.765 -47.783 1.00 54.10  ? 116 THR C O   1 
ATOM   4242 C CB  . THR C 3 120 ? 4.475   -44.860 -46.565 1.00 46.75  ? 116 THR C CB  1 
ATOM   4243 O OG1 . THR C 3 120 ? 4.059   -43.526 -46.241 1.00 37.25  ? 116 THR C OG1 1 
ATOM   4244 C CG2 . THR C 3 120 ? 3.657   -45.854 -45.757 1.00 43.59  ? 116 THR C CG2 1 
ATOM   4245 N N   . LYS C 3 121 ? 6.645   -47.243 -45.580 1.00 33.74  ? 117 LYS C N   1 
ATOM   4246 C CA  . LYS C 3 121 ? 7.040   -48.630 -45.761 1.00 41.89  ? 117 LYS C CA  1 
ATOM   4247 C C   . LYS C 3 121 ? 6.255   -49.508 -44.799 1.00 47.86  ? 117 LYS C C   1 
ATOM   4248 O O   . LYS C 3 121 ? 6.090   -49.165 -43.625 1.00 46.97  ? 117 LYS C O   1 
ATOM   4249 C CB  . LYS C 3 121 ? 8.541   -48.819 -45.535 1.00 44.69  ? 117 LYS C CB  1 
ATOM   4250 C CG  . LYS C 3 121 ? 9.052   -50.177 -45.949 1.00 49.66  ? 117 LYS C CG  1 
ATOM   4251 C CD  . LYS C 3 121 ? 10.446  -50.427 -45.397 1.00 49.40  ? 117 LYS C CD  1 
ATOM   4252 C CE  . LYS C 3 121 ? 10.634  -51.910 -45.072 1.00 53.17  ? 117 LYS C CE  1 
ATOM   4253 N NZ  . LYS C 3 121 ? 9.574   -52.358 -44.095 1.00 69.64  ? 117 LYS C NZ  1 
ATOM   4254 N N   . GLY C 3 122 ? 5.779   -50.641 -45.305 1.00 48.40  ? 118 GLY C N   1 
ATOM   4255 C CA  . GLY C 3 122 ? 4.968   -51.543 -44.524 1.00 50.85  ? 118 GLY C CA  1 
ATOM   4256 C C   . GLY C 3 122 ? 5.770   -52.337 -43.513 1.00 53.49  ? 118 GLY C C   1 
ATOM   4257 O O   . GLY C 3 122 ? 6.981   -52.533 -43.657 1.00 62.82  ? 118 GLY C O   1 
ATOM   4258 N N   . PRO C 3 123 ? 5.102   -52.811 -42.467 1.00 53.61  ? 119 PRO C N   1 
ATOM   4259 C CA  . PRO C 3 123 ? 5.791   -53.592 -41.437 1.00 59.30  ? 119 PRO C CA  1 
ATOM   4260 C C   . PRO C 3 123 ? 5.921   -55.060 -41.819 1.00 59.02  ? 119 PRO C C   1 
ATOM   4261 O O   . PRO C 3 123 ? 5.242   -55.569 -42.713 1.00 47.28  ? 119 PRO C O   1 
ATOM   4262 C CB  . PRO C 3 123 ? 4.884   -53.426 -40.215 1.00 55.03  ? 119 PRO C CB  1 
ATOM   4263 C CG  . PRO C 3 123 ? 3.521   -53.295 -40.805 1.00 56.10  ? 119 PRO C CG  1 
ATOM   4264 C CD  . PRO C 3 123 ? 3.696   -52.552 -42.112 1.00 61.94  ? 119 PRO C CD  1 
ATOM   4265 N N   . SER C 3 124 ? 6.822   -55.736 -41.112 1.00 54.17  ? 120 SER C N   1 
ATOM   4266 C CA  . SER C 3 124 ? 7.027   -57.172 -41.239 1.00 39.67  ? 120 SER C CA  1 
ATOM   4267 C C   . SER C 3 124 ? 6.874   -57.803 -39.863 1.00 50.69  ? 120 SER C C   1 
ATOM   4268 O O   . SER C 3 124 ? 7.433   -57.301 -38.883 1.00 64.99  ? 120 SER C O   1 
ATOM   4269 C CB  . SER C 3 124 ? 8.406   -57.486 -41.824 1.00 43.68  ? 120 SER C CB  1 
ATOM   4270 O OG  . SER C 3 124 ? 8.639   -56.741 -43.007 1.00 47.52  ? 120 SER C OG  1 
ATOM   4271 N N   . VAL C 3 125 ? 6.121   -58.897 -39.792 1.00 55.16  ? 121 VAL C N   1 
ATOM   4272 C CA  . VAL C 3 125 ? 5.778   -59.545 -38.531 1.00 59.35  ? 121 VAL C CA  1 
ATOM   4273 C C   . VAL C 3 125 ? 6.523   -60.869 -38.441 1.00 62.43  ? 121 VAL C C   1 
ATOM   4274 O O   . VAL C 3 125 ? 6.502   -61.667 -39.386 1.00 75.09  ? 121 VAL C O   1 
ATOM   4275 C CB  . VAL C 3 125 ? 4.261   -59.757 -38.404 1.00 55.46  ? 121 VAL C CB  1 
ATOM   4276 C CG1 . VAL C 3 125 ? 3.914   -60.337 -37.040 1.00 64.91  ? 121 VAL C CG1 1 
ATOM   4277 C CG2 . VAL C 3 125 ? 3.531   -58.447 -38.641 1.00 37.08  ? 121 VAL C CG2 1 
ATOM   4278 N N   . PHE C 3 126 ? 7.175   -61.099 -37.305 1.00 50.83  ? 122 PHE C N   1 
ATOM   4279 C CA  . PHE C 3 126 ? 7.895   -62.333 -37.042 1.00 49.17  ? 122 PHE C CA  1 
ATOM   4280 C C   . PHE C 3 126 ? 7.457   -62.911 -35.706 1.00 54.94  ? 122 PHE C C   1 
ATOM   4281 O O   . PHE C 3 126 ? 7.164   -62.164 -34.766 1.00 63.27  ? 122 PHE C O   1 
ATOM   4282 C CB  . PHE C 3 126 ? 9.412   -62.098 -37.030 1.00 56.13  ? 122 PHE C CB  1 
ATOM   4283 C CG  . PHE C 3 126 ? 9.921   -61.371 -38.242 1.00 53.52  ? 122 PHE C CG  1 
ATOM   4284 C CD1 . PHE C 3 126 ? 9.999   -62.010 -39.468 1.00 58.26  ? 122 PHE C CD1 1 
ATOM   4285 C CD2 . PHE C 3 126 ? 10.326  -60.050 -38.154 1.00 51.29  ? 122 PHE C CD2 1 
ATOM   4286 C CE1 . PHE C 3 126 ? 10.468  -61.343 -40.585 1.00 47.66  ? 122 PHE C CE1 1 
ATOM   4287 C CE2 . PHE C 3 126 ? 10.798  -59.378 -39.267 1.00 48.34  ? 122 PHE C CE2 1 
ATOM   4288 C CZ  . PHE C 3 126 ? 10.869  -60.025 -40.483 1.00 36.79  ? 122 PHE C CZ  1 
ATOM   4289 N N   . PRO C 3 127 ? 7.403   -64.238 -35.592 1.00 54.25  ? 123 PRO C N   1 
ATOM   4290 C CA  . PRO C 3 127 ? 6.907   -64.860 -34.355 1.00 66.89  ? 123 PRO C CA  1 
ATOM   4291 C C   . PRO C 3 127 ? 7.984   -64.897 -33.278 1.00 69.88  ? 123 PRO C C   1 
ATOM   4292 O O   . PRO C 3 127 ? 9.113   -65.326 -33.524 1.00 69.81  ? 123 PRO C O   1 
ATOM   4293 C CB  . PRO C 3 127 ? 6.518   -66.278 -34.797 1.00 72.44  ? 123 PRO C CB  1 
ATOM   4294 C CG  . PRO C 3 127 ? 6.606   -66.279 -36.309 1.00 74.93  ? 123 PRO C CG  1 
ATOM   4295 C CD  . PRO C 3 127 ? 7.608   -65.230 -36.657 1.00 62.98  ? 123 PRO C CD  1 
ATOM   4296 N N   . LEU C 3 128 ? 7.624   -64.442 -32.076 1.00 57.68  ? 124 LEU C N   1 
ATOM   4297 C CA  . LEU C 3 128 ? 8.466   -64.620 -30.893 1.00 63.32  ? 124 LEU C CA  1 
ATOM   4298 C C   . LEU C 3 128 ? 8.015   -65.910 -30.213 1.00 67.65  ? 124 LEU C C   1 
ATOM   4299 O O   . LEU C 3 128 ? 7.263   -65.915 -29.237 1.00 81.52  ? 124 LEU C O   1 
ATOM   4300 C CB  . LEU C 3 128 ? 8.370   -63.413 -29.970 1.00 56.82  ? 124 LEU C CB  1 
ATOM   4301 C CG  . LEU C 3 128 ? 8.735   -62.067 -30.602 1.00 54.23  ? 124 LEU C CG  1 
ATOM   4302 C CD1 . LEU C 3 128 ? 8.688   -60.951 -29.570 1.00 57.76  ? 124 LEU C CD1 1 
ATOM   4303 C CD2 . LEU C 3 128 ? 10.103  -62.136 -31.264 1.00 50.94  ? 124 LEU C CD2 1 
ATOM   4304 N N   . ALA C 3 129 ? 8.483   -67.023 -30.761 1.00 69.27  ? 125 ALA C N   1 
ATOM   4305 C CA  . ALA C 3 129 ? 7.961   -68.331 -30.383 1.00 78.57  ? 125 ALA C CA  1 
ATOM   4306 C C   . ALA C 3 129 ? 8.312   -68.665 -28.937 1.00 84.83  ? 125 ALA C C   1 
ATOM   4307 O O   . ALA C 3 129 ? 9.477   -68.533 -28.540 1.00 86.60  ? 125 ALA C O   1 
ATOM   4308 C CB  . ALA C 3 129 ? 8.510   -69.405 -31.316 1.00 80.00  ? 125 ALA C CB  1 
ATOM   4309 N N   . PRO C 3 130 ? 7.347   -69.086 -28.125 1.00 82.81  ? 126 PRO C N   1 
ATOM   4310 C CA  . PRO C 3 130 ? 7.677   -69.573 -26.783 1.00 85.13  ? 126 PRO C CA  1 
ATOM   4311 C C   . PRO C 3 130 ? 8.413   -70.901 -26.855 1.00 88.57  ? 126 PRO C C   1 
ATOM   4312 O O   . PRO C 3 130 ? 8.196   -71.707 -27.763 1.00 77.82  ? 126 PRO C O   1 
ATOM   4313 C CB  . PRO C 3 130 ? 6.305   -69.735 -26.120 1.00 80.15  ? 126 PRO C CB  1 
ATOM   4314 C CG  . PRO C 3 130 ? 5.392   -70.020 -27.267 1.00 85.87  ? 126 PRO C CG  1 
ATOM   4315 C CD  . PRO C 3 130 ? 5.916   -69.232 -28.435 1.00 75.27  ? 126 PRO C CD  1 
ATOM   4316 N N   . SER C 3 131 ? 9.291   -71.124 -25.882 1.00 88.88  ? 127 SER C N   1 
ATOM   4317 C CA  . SER C 3 131 ? 10.093  -72.336 -25.866 1.00 89.37  ? 127 SER C CA  1 
ATOM   4318 C C   . SER C 3 131 ? 10.586  -72.597 -24.451 1.00 99.85  ? 127 SER C C   1 
ATOM   4319 O O   . SER C 3 131 ? 10.801  -71.664 -23.673 1.00 84.86  ? 127 SER C O   1 
ATOM   4320 C CB  . SER C 3 131 ? 11.279  -72.234 -26.832 1.00 77.17  ? 127 SER C CB  1 
ATOM   4321 O OG  . SER C 3 131 ? 12.121  -71.148 -26.489 1.00 86.29  ? 127 SER C OG  1 
ATOM   4322 N N   . SER C 3 132 ? 10.759  -73.880 -24.136 1.00 92.62  ? 128 SER C N   1 
ATOM   4323 C CA  . SER C 3 132 ? 11.303  -74.320 -22.854 1.00 77.08  ? 128 SER C CA  1 
ATOM   4324 C C   . SER C 3 132 ? 10.524  -73.755 -21.669 1.00 84.57  ? 128 SER C C   1 
ATOM   4325 O O   . SER C 3 132 ? 10.163  -74.484 -20.745 1.00 78.42  ? 128 SER C O   1 
ATOM   4326 C CB  . SER C 3 132 ? 12.780  -73.931 -22.744 1.00 70.86  ? 128 SER C CB  1 
ATOM   4327 O OG  . SER C 3 132 ? 13.527  -74.468 -23.822 1.00 83.12  ? 128 SER C OG  1 
ATOM   4328 N N   . GLY C 3 138 ? 5.184   -73.354 -15.372 1.00 86.71  ? 134 GLY C N   1 
ATOM   4329 C CA  . GLY C 3 138 ? 3.741   -73.238 -15.280 1.00 65.82  ? 134 GLY C CA  1 
ATOM   4330 C C   . GLY C 3 138 ? 3.151   -72.277 -16.293 1.00 86.86  ? 134 GLY C C   1 
ATOM   4331 O O   . GLY C 3 138 ? 2.087   -72.532 -16.857 1.00 95.60  ? 134 GLY C O   1 
ATOM   4332 N N   . THR C 3 139 ? 3.848   -71.169 -16.525 1.00 101.20 ? 135 THR C N   1 
ATOM   4333 C CA  . THR C 3 139 ? 3.413   -70.145 -17.461 1.00 100.38 ? 135 THR C CA  1 
ATOM   4334 C C   . THR C 3 139 ? 4.424   -70.002 -18.591 1.00 101.69 ? 135 THR C C   1 
ATOM   4335 O O   . THR C 3 139 ? 5.560   -70.477 -18.504 1.00 99.43  ? 135 THR C O   1 
ATOM   4336 C CB  . THR C 3 139 ? 3.224   -68.794 -16.761 1.00 84.32  ? 135 THR C CB  1 
ATOM   4337 O OG1 . THR C 3 139 ? 2.948   -67.781 -17.736 1.00 82.18  ? 135 THR C OG1 1 
ATOM   4338 C CG2 . THR C 3 139 ? 4.478   -68.416 -15.985 1.00 75.92  ? 135 THR C CG2 1 
ATOM   4339 N N   . ALA C 3 140 ? 3.992   -69.340 -19.662 1.00 92.71  ? 136 ALA C N   1 
ATOM   4340 C CA  . ALA C 3 140 ? 4.848   -69.100 -20.814 1.00 84.74  ? 136 ALA C CA  1 
ATOM   4341 C C   . ALA C 3 140 ? 4.506   -67.743 -21.411 1.00 83.06  ? 136 ALA C C   1 
ATOM   4342 O O   . ALA C 3 140 ? 3.406   -67.218 -21.222 1.00 80.67  ? 136 ALA C O   1 
ATOM   4343 C CB  . ALA C 3 140 ? 4.701   -70.205 -21.867 1.00 84.89  ? 136 ALA C CB  1 
ATOM   4344 N N   . ALA C 3 141 ? 5.468   -67.179 -22.138 1.00 97.31  ? 137 ALA C N   1 
ATOM   4345 C CA  . ALA C 3 141 ? 5.301   -65.884 -22.781 1.00 86.08  ? 137 ALA C CA  1 
ATOM   4346 C C   . ALA C 3 141 ? 5.649   -65.992 -24.258 1.00 81.91  ? 137 ALA C C   1 
ATOM   4347 O O   . ALA C 3 141 ? 6.527   -66.765 -24.653 1.00 75.54  ? 137 ALA C O   1 
ATOM   4348 C CB  . ALA C 3 141 ? 6.168   -64.808 -22.118 1.00 69.34  ? 137 ALA C CB  1 
ATOM   4349 N N   . LEU C 3 142 ? 4.952   -65.201 -25.069 1.00 72.30  ? 138 LEU C N   1 
ATOM   4350 C CA  . LEU C 3 142 ? 5.122   -65.232 -26.515 1.00 81.06  ? 138 LEU C CA  1 
ATOM   4351 C C   . LEU C 3 142 ? 4.673   -63.892 -27.081 1.00 76.22  ? 138 LEU C C   1 
ATOM   4352 O O   . LEU C 3 142 ? 4.062   -63.077 -26.385 1.00 68.56  ? 138 LEU C O   1 
ATOM   4353 C CB  . LEU C 3 142 ? 4.341   -66.393 -27.140 1.00 89.13  ? 138 LEU C CB  1 
ATOM   4354 C CG  . LEU C 3 142 ? 2.863   -66.545 -26.772 1.00 85.49  ? 138 LEU C CG  1 
ATOM   4355 C CD1 . LEU C 3 142 ? 1.977   -65.817 -27.765 1.00 67.35  ? 138 LEU C CD1 1 
ATOM   4356 C CD2 . LEU C 3 142 ? 2.477   -68.012 -26.689 1.00 78.92  ? 138 LEU C CD2 1 
ATOM   4357 N N   . GLY C 3 143 ? 4.987   -63.670 -28.351 1.00 55.96  ? 139 GLY C N   1 
ATOM   4358 C CA  . GLY C 3 143 ? 4.602   -62.419 -28.971 1.00 57.16  ? 139 GLY C CA  1 
ATOM   4359 C C   . GLY C 3 143 ? 4.968   -62.369 -30.438 1.00 64.79  ? 139 GLY C C   1 
ATOM   4360 O O   . GLY C 3 143 ? 5.394   -63.362 -31.032 1.00 65.47  ? 139 GLY C O   1 
ATOM   4361 N N   . CYS C 3 144 ? 4.775   -61.183 -31.014 1.00 56.36  ? 140 CYS C N   1 
ATOM   4362 C CA  . CYS C 3 144 ? 5.085   -60.906 -32.408 1.00 56.66  ? 140 CYS C CA  1 
ATOM   4363 C C   . CYS C 3 144 ? 5.973   -59.673 -32.493 1.00 60.51  ? 140 CYS C C   1 
ATOM   4364 O O   . CYS C 3 144 ? 5.842   -58.737 -31.699 1.00 61.61  ? 140 CYS C O   1 
ATOM   4365 C CB  . CYS C 3 144 ? 3.808   -60.688 -33.241 1.00 62.96  ? 140 CYS C CB  1 
ATOM   4366 S SG  . CYS C 3 144 ? 2.816   -62.180 -33.506 1.00 107.11 ? 140 CYS C SG  1 
ATOM   4367 N N   . LEU C 3 145 ? 6.881   -59.680 -33.465 1.00 58.82  ? 141 LEU C N   1 
ATOM   4368 C CA  . LEU C 3 145 ? 7.825   -58.589 -33.676 1.00 49.15  ? 141 LEU C CA  1 
ATOM   4369 C C   . LEU C 3 145 ? 7.419   -57.808 -34.919 1.00 44.16  ? 141 LEU C C   1 
ATOM   4370 O O   . LEU C 3 145 ? 7.443   -58.348 -36.031 1.00 51.49  ? 141 LEU C O   1 
ATOM   4371 C CB  . LEU C 3 145 ? 9.251   -59.120 -33.818 1.00 55.94  ? 141 LEU C CB  1 
ATOM   4372 C CG  . LEU C 3 145 ? 10.320  -58.113 -34.250 1.00 41.37  ? 141 LEU C CG  1 
ATOM   4373 C CD1 . LEU C 3 145 ? 10.421  -56.968 -33.256 1.00 39.97  ? 141 LEU C CD1 1 
ATOM   4374 C CD2 . LEU C 3 145 ? 11.666  -58.800 -34.422 1.00 37.19  ? 141 LEU C CD2 1 
ATOM   4375 N N   . VAL C 3 146 ? 7.062   -56.541 -34.729 1.00 37.20  ? 142 VAL C N   1 
ATOM   4376 C CA  . VAL C 3 146 ? 6.683   -55.643 -35.814 1.00 37.91  ? 142 VAL C CA  1 
ATOM   4377 C C   . VAL C 3 146 ? 7.863   -54.713 -36.064 1.00 51.54  ? 142 VAL C C   1 
ATOM   4378 O O   . VAL C 3 146 ? 8.142   -53.817 -35.259 1.00 58.66  ? 142 VAL C O   1 
ATOM   4379 C CB  . VAL C 3 146 ? 5.408   -54.858 -35.475 1.00 41.09  ? 142 VAL C CB  1 
ATOM   4380 C CG1 . VAL C 3 146 ? 4.881   -54.134 -36.702 1.00 48.45  ? 142 VAL C CG1 1 
ATOM   4381 C CG2 . VAL C 3 146 ? 4.348   -55.786 -34.896 1.00 46.79  ? 142 VAL C CG2 1 
ATOM   4382 N N   . LYS C 3 147 ? 8.548   -54.910 -37.188 1.00 44.63  ? 143 LYS C N   1 
ATOM   4383 C CA  . LYS C 3 147 ? 9.831   -54.271 -37.443 1.00 45.66  ? 143 LYS C CA  1 
ATOM   4384 C C   . LYS C 3 147 ? 9.824   -53.591 -38.806 1.00 46.99  ? 143 LYS C C   1 
ATOM   4385 O O   . LYS C 3 147 ? 9.151   -54.037 -39.739 1.00 50.36  ? 143 LYS C O   1 
ATOM   4386 C CB  . LYS C 3 147 ? 10.977  -55.303 -37.373 1.00 44.30  ? 143 LYS C CB  1 
ATOM   4387 C CG  . LYS C 3 147 ? 12.381  -54.736 -37.521 1.00 53.59  ? 143 LYS C CG  1 
ATOM   4388 C CD  . LYS C 3 147 ? 13.427  -55.837 -37.470 1.00 50.77  ? 143 LYS C CD  1 
ATOM   4389 C CE  . LYS C 3 147 ? 14.824  -55.261 -37.610 1.00 57.41  ? 143 LYS C CE  1 
ATOM   4390 N NZ  . LYS C 3 147 ? 15.021  -54.613 -38.937 1.00 57.69  ? 143 LYS C NZ  1 
ATOM   4391 N N   . ASP C 3 148 ? 10.588  -52.503 -38.908 1.00 56.61  ? 144 ASP C N   1 
ATOM   4392 C CA  . ASP C 3 148 ? 10.867  -51.837 -40.183 1.00 56.92  ? 144 ASP C CA  1 
ATOM   4393 C C   . ASP C 3 148 ? 9.584   -51.338 -40.858 1.00 53.43  ? 144 ASP C C   1 
ATOM   4394 O O   . ASP C 3 148 ? 9.160   -51.823 -41.907 1.00 59.91  ? 144 ASP C O   1 
ATOM   4395 C CB  . ASP C 3 148 ? 11.645  -52.765 -41.122 1.00 59.55  ? 144 ASP C CB  1 
ATOM   4396 C CG  . ASP C 3 148 ? 13.112  -52.880 -40.748 1.00 68.39  ? 144 ASP C CG  1 
ATOM   4397 O OD1 . ASP C 3 148 ? 13.520  -52.302 -39.718 1.00 68.66  ? 144 ASP C OD1 1 
ATOM   4398 O OD2 . ASP C 3 148 ? 13.866  -53.536 -41.498 1.00 79.68  ? 144 ASP C OD2 1 
ATOM   4399 N N   . TYR C 3 149 ? 8.963   -50.357 -40.208 1.00 45.72  ? 145 TYR C N   1 
ATOM   4400 C CA  . TYR C 3 149 ? 7.839   -49.653 -40.801 1.00 52.93  ? 145 TYR C CA  1 
ATOM   4401 C C   . TYR C 3 149 ? 8.009   -48.155 -40.591 1.00 46.00  ? 145 TYR C C   1 
ATOM   4402 O O   . TYR C 3 149 ? 8.741   -47.703 -39.706 1.00 53.18  ? 145 TYR C O   1 
ATOM   4403 C CB  . TYR C 3 149 ? 6.493   -50.126 -40.228 1.00 50.01  ? 145 TYR C CB  1 
ATOM   4404 C CG  . TYR C 3 149 ? 6.233   -49.737 -38.789 1.00 44.08  ? 145 TYR C CG  1 
ATOM   4405 C CD1 . TYR C 3 149 ? 5.682   -48.500 -38.467 1.00 39.67  ? 145 TYR C CD1 1 
ATOM   4406 C CD2 . TYR C 3 149 ? 6.518   -50.614 -37.754 1.00 50.74  ? 145 TYR C CD2 1 
ATOM   4407 C CE1 . TYR C 3 149 ? 5.443   -48.143 -37.153 1.00 49.63  ? 145 TYR C CE1 1 
ATOM   4408 C CE2 . TYR C 3 149 ? 6.279   -50.268 -36.438 1.00 53.15  ? 145 TYR C CE2 1 
ATOM   4409 C CZ  . TYR C 3 149 ? 5.740   -49.030 -36.144 1.00 53.68  ? 145 TYR C CZ  1 
ATOM   4410 O OH  . TYR C 3 149 ? 5.495   -48.668 -34.841 1.00 46.79  ? 145 TYR C OH  1 
ATOM   4411 N N   . PHE C 3 150 ? 7.319   -47.388 -41.439 1.00 47.16  ? 146 PHE C N   1 
ATOM   4412 C CA  . PHE C 3 150 ? 7.295   -45.937 -41.358 1.00 54.45  ? 146 PHE C CA  1 
ATOM   4413 C C   . PHE C 3 150 ? 6.112   -45.433 -42.165 1.00 59.15  ? 146 PHE C C   1 
ATOM   4414 O O   . PHE C 3 150 ? 5.882   -45.933 -43.274 1.00 58.67  ? 146 PHE C O   1 
ATOM   4415 C CB  . PHE C 3 150 ? 8.597   -45.324 -41.886 1.00 37.34  ? 146 PHE C CB  1 
ATOM   4416 C CG  . PHE C 3 150 ? 8.669   -43.830 -41.732 1.00 47.41  ? 146 PHE C CG  1 
ATOM   4417 C CD1 . PHE C 3 150 ? 9.114   -43.265 -40.548 1.00 52.70  ? 146 PHE C CD1 1 
ATOM   4418 C CD2 . PHE C 3 150 ? 8.292   -42.991 -42.770 1.00 42.22  ? 146 PHE C CD2 1 
ATOM   4419 C CE1 . PHE C 3 150 ? 9.181   -41.894 -40.401 1.00 48.81  ? 146 PHE C CE1 1 
ATOM   4420 C CE2 . PHE C 3 150 ? 8.357   -41.619 -42.626 1.00 44.16  ? 146 PHE C CE2 1 
ATOM   4421 C CZ  . PHE C 3 150 ? 8.803   -41.070 -41.442 1.00 41.19  ? 146 PHE C CZ  1 
ATOM   4422 N N   . PRO C 3 151 ? 5.338   -44.467 -41.650 1.00 54.19  ? 147 PRO C N   1 
ATOM   4423 C CA  . PRO C 3 151 ? 5.441   -43.860 -40.321 1.00 51.18  ? 147 PRO C CA  1 
ATOM   4424 C C   . PRO C 3 151 ? 4.568   -44.580 -39.300 1.00 47.78  ? 147 PRO C C   1 
ATOM   4425 O O   . PRO C 3 151 ? 3.893   -45.557 -39.615 1.00 58.20  ? 147 PRO C O   1 
ATOM   4426 C CB  . PRO C 3 151 ? 4.963   -42.428 -40.575 1.00 51.23  ? 147 PRO C CB  1 
ATOM   4427 C CG  . PRO C 3 151 ? 3.875   -42.613 -41.600 1.00 43.29  ? 147 PRO C CG  1 
ATOM   4428 C CD  . PRO C 3 151 ? 4.336   -43.769 -42.478 1.00 53.86  ? 147 PRO C CD  1 
ATOM   4429 N N   . GLU C 3 152 ? 4.579   -44.110 -38.058 1.00 52.90  ? 148 GLU C N   1 
ATOM   4430 C CA  . GLU C 3 152 ? 3.665   -44.589 -37.038 1.00 57.19  ? 148 GLU C CA  1 
ATOM   4431 C C   . GLU C 3 152 ? 2.275   -44.011 -37.295 1.00 51.35  ? 148 GLU C C   1 
ATOM   4432 O O   . GLU C 3 152 ? 2.121   -43.064 -38.070 1.00 59.93  ? 148 GLU C O   1 
ATOM   4433 C CB  . GLU C 3 152 ? 4.200   -44.211 -35.656 1.00 48.08  ? 148 GLU C CB  1 
ATOM   4434 C CG  . GLU C 3 152 ? 4.645   -45.407 -34.827 1.00 49.23  ? 148 GLU C CG  1 
ATOM   4435 C CD  . GLU C 3 152 ? 4.651   -45.114 -33.342 1.00 70.59  ? 148 GLU C CD  1 
ATOM   4436 O OE1 . GLU C 3 152 ? 5.231   -44.083 -32.941 1.00 74.91  ? 148 GLU C OE1 1 
ATOM   4437 O OE2 . GLU C 3 152 ? 4.062   -45.908 -32.577 1.00 63.57  ? 148 GLU C OE2 1 
ATOM   4438 N N   . PRO C 3 153 ? 1.220   -44.560 -36.663 1.00 51.60  ? 149 PRO C N   1 
ATOM   4439 C CA  . PRO C 3 153 ? 1.175   -45.649 -35.675 1.00 55.01  ? 149 PRO C CA  1 
ATOM   4440 C C   . PRO C 3 153 ? 0.828   -47.019 -36.242 1.00 50.51  ? 149 PRO C C   1 
ATOM   4441 O O   . PRO C 3 153 ? 0.473   -47.176 -37.407 1.00 49.74  ? 149 PRO C O   1 
ATOM   4442 C CB  . PRO C 3 153 ? 0.085   -45.171 -34.693 1.00 56.85  ? 149 PRO C CB  1 
ATOM   4443 C CG  . PRO C 3 153 ? -0.597  -43.957 -35.349 1.00 57.04  ? 149 PRO C CG  1 
ATOM   4444 C CD  . PRO C 3 153 ? -0.094  -43.915 -36.764 1.00 65.25  ? 149 PRO C CD  1 
ATOM   4445 N N   . VAL C 3 154 ? 0.940   -48.035 -35.389 1.00 51.06  ? 150 VAL C N   1 
ATOM   4446 C CA  . VAL C 3 154 ? 0.587   -49.410 -35.715 1.00 47.15  ? 150 VAL C CA  1 
ATOM   4447 C C   . VAL C 3 154 ? -0.225  -49.971 -34.556 1.00 60.73  ? 150 VAL C C   1 
ATOM   4448 O O   . VAL C 3 154 ? 0.144   -49.787 -33.391 1.00 62.71  ? 150 VAL C O   1 
ATOM   4449 C CB  . VAL C 3 154 ? 1.837   -50.274 -35.976 1.00 45.08  ? 150 VAL C CB  1 
ATOM   4450 C CG1 . VAL C 3 154 ? 1.495   -51.752 -35.910 1.00 55.19  ? 150 VAL C CG1 1 
ATOM   4451 C CG2 . VAL C 3 154 ? 2.442   -49.934 -37.326 1.00 42.25  ? 150 VAL C CG2 1 
ATOM   4452 N N   . THR C 3 155 ? -1.328  -50.644 -34.871 1.00 66.21  ? 151 THR C N   1 
ATOM   4453 C CA  . THR C 3 155 ? -2.186  -51.262 -33.871 1.00 58.44  ? 151 THR C CA  1 
ATOM   4454 C C   . THR C 3 155 ? -2.021  -52.775 -33.915 1.00 51.36  ? 151 THR C C   1 
ATOM   4455 O O   . THR C 3 155 ? -1.947  -53.370 -34.995 1.00 54.55  ? 151 THR C O   1 
ATOM   4456 C CB  . THR C 3 155 ? -3.655  -50.893 -34.093 1.00 65.82  ? 151 THR C CB  1 
ATOM   4457 O OG1 . THR C 3 155 ? -4.094  -51.404 -35.358 1.00 72.47  ? 151 THR C OG1 1 
ATOM   4458 C CG2 . THR C 3 155 ? -3.830  -49.383 -34.072 1.00 52.04  ? 151 THR C CG2 1 
ATOM   4459 N N   . VAL C 3 156 ? -1.949  -53.392 -32.736 1.00 53.57  ? 152 VAL C N   1 
ATOM   4460 C CA  . VAL C 3 156 ? -1.756  -54.831 -32.607 1.00 68.42  ? 152 VAL C CA  1 
ATOM   4461 C C   . VAL C 3 156 ? -2.871  -55.398 -31.739 1.00 71.49  ? 152 VAL C C   1 
ATOM   4462 O O   . VAL C 3 156 ? -3.185  -54.840 -30.682 1.00 72.06  ? 152 VAL C O   1 
ATOM   4463 C CB  . VAL C 3 156 ? -0.380  -55.178 -32.007 1.00 65.08  ? 152 VAL C CB  1 
ATOM   4464 C CG1 . VAL C 3 156 ? -0.018  -56.624 -32.316 1.00 64.51  ? 152 VAL C CG1 1 
ATOM   4465 C CG2 . VAL C 3 156 ? 0.691   -54.228 -32.523 1.00 59.12  ? 152 VAL C CG2 1 
ATOM   4466 N N   . SER C 3 157 ? -3.470  -56.501 -32.188 1.00 66.24  ? 153 SER C N   1 
ATOM   4467 C CA  . SER C 3 157 ? -4.472  -57.222 -31.417 1.00 75.83  ? 153 SER C CA  1 
ATOM   4468 C C   . SER C 3 157 ? -4.176  -58.715 -31.485 1.00 88.59  ? 153 SER C C   1 
ATOM   4469 O O   . SER C 3 157 ? -3.536  -59.201 -32.422 1.00 95.62  ? 153 SER C O   1 
ATOM   4470 C CB  . SER C 3 157 ? -5.895  -56.938 -31.918 1.00 82.67  ? 153 SER C CB  1 
ATOM   4471 O OG  . SER C 3 157 ? -6.124  -57.522 -33.187 1.00 84.00  ? 153 SER C OG  1 
ATOM   4472 N N   . TRP C 3 158 ? -4.651  -59.443 -30.477 1.00 84.77  ? 154 TRP C N   1 
ATOM   4473 C CA  . TRP C 3 158 ? -4.334  -60.856 -30.310 1.00 98.68  ? 154 TRP C CA  1 
ATOM   4474 C C   . TRP C 3 158 ? -5.601  -61.695 -30.377 1.00 104.86 ? 154 TRP C C   1 
ATOM   4475 O O   . TRP C 3 158 ? -6.613  -61.352 -29.757 1.00 104.83 ? 154 TRP C O   1 
ATOM   4476 C CB  . TRP C 3 158 ? -3.606  -61.095 -28.986 1.00 90.35  ? 154 TRP C CB  1 
ATOM   4477 C CG  . TRP C 3 158 ? -2.174  -60.678 -29.035 1.00 81.49  ? 154 TRP C CG  1 
ATOM   4478 C CD1 . TRP C 3 158 ? -1.651  -59.484 -28.634 1.00 72.29  ? 154 TRP C CD1 1 
ATOM   4479 C CD2 . TRP C 3 158 ? -1.078  -61.451 -29.534 1.00 81.60  ? 154 TRP C CD2 1 
ATOM   4480 N NE1 . TRP C 3 158 ? -0.293  -59.469 -28.845 1.00 76.09  ? 154 TRP C NE1 1 
ATOM   4481 C CE2 . TRP C 3 158 ? 0.083   -60.665 -29.397 1.00 85.36  ? 154 TRP C CE2 1 
ATOM   4482 C CE3 . TRP C 3 158 ? -0.964  -62.733 -30.079 1.00 77.87  ? 154 TRP C CE3 1 
ATOM   4483 C CZ2 . TRP C 3 158 ? 1.340   -61.120 -29.786 1.00 82.09  ? 154 TRP C CZ2 1 
ATOM   4484 C CZ3 . TRP C 3 158 ? 0.284   -63.183 -30.463 1.00 74.03  ? 154 TRP C CZ3 1 
ATOM   4485 C CH2 . TRP C 3 158 ? 1.419   -62.379 -30.316 1.00 72.56  ? 154 TRP C CH2 1 
ATOM   4486 N N   . ASN C 3 159 ? -5.528  -62.799 -31.127 1.00 102.96 ? 155 ASN C N   1 
ATOM   4487 C CA  . ASN C 3 159 ? -6.650  -63.722 -31.311 1.00 92.71  ? 155 ASN C CA  1 
ATOM   4488 C C   . ASN C 3 159 ? -7.887  -62.999 -31.837 1.00 100.63 ? 155 ASN C C   1 
ATOM   4489 O O   . ASN C 3 159 ? -9.017  -63.291 -31.438 1.00 103.47 ? 155 ASN C O   1 
ATOM   4490 C CB  . ASN C 3 159 ? -6.962  -64.482 -30.020 1.00 84.37  ? 155 ASN C CB  1 
ATOM   4491 C CG  . ASN C 3 159 ? -6.061  -65.684 -29.826 1.00 95.77  ? 155 ASN C CG  1 
ATOM   4492 O OD1 . ASN C 3 159 ? -5.091  -65.869 -30.562 1.00 100.43 ? 155 ASN C OD1 1 
ATOM   4493 N ND2 . ASN C 3 159 ? -6.378  -66.510 -28.837 1.00 93.92  ? 155 ASN C ND2 1 
ATOM   4494 N N   . SER C 3 160 ? -7.663  -62.043 -32.739 1.00 100.48 ? 156 SER C N   1 
ATOM   4495 C CA  . SER C 3 160 ? -8.729  -61.335 -33.448 1.00 91.94  ? 156 SER C CA  1 
ATOM   4496 C C   . SER C 3 160 ? -9.702  -60.655 -32.482 1.00 97.06  ? 156 SER C C   1 
ATOM   4497 O O   . SER C 3 160 ? -10.879 -61.001 -32.393 1.00 111.50 ? 156 SER C O   1 
ATOM   4498 C CB  . SER C 3 160 ? -9.476  -62.282 -34.397 1.00 91.95  ? 156 SER C CB  1 
ATOM   4499 O OG  . SER C 3 160 ? -8.620  -62.779 -35.411 1.00 87.82  ? 156 SER C OG  1 
ATOM   4500 N N   . GLY C 3 161 ? -9.185  -59.672 -31.747 1.00 87.53  ? 157 GLY C N   1 
ATOM   4501 C CA  . GLY C 3 161 ? -10.038 -58.880 -30.881 1.00 78.42  ? 157 GLY C CA  1 
ATOM   4502 C C   . GLY C 3 161 ? -10.577 -59.609 -29.667 1.00 91.38  ? 157 GLY C C   1 
ATOM   4503 O O   . GLY C 3 161 ? -11.778 -59.884 -29.588 1.00 107.22 ? 157 GLY C O   1 
ATOM   4504 N N   . ALA C 3 162 ? -9.692  -59.937 -28.728 1.00 94.64  ? 158 ALA C N   1 
ATOM   4505 C CA  . ALA C 3 162 ? -10.063 -60.611 -27.486 1.00 90.79  ? 158 ALA C CA  1 
ATOM   4506 C C   . ALA C 3 162 ? -10.659 -61.986 -27.759 1.00 94.71  ? 158 ALA C C   1 
ATOM   4507 O O   . ALA C 3 162 ? -9.984  -63.004 -27.607 1.00 75.34  ? 158 ALA C O   1 
ATOM   4508 C CB  . ALA C 3 162 ? -11.037 -59.753 -26.672 1.00 76.57  ? 158 ALA C CB  1 
ATOM   4509 N N   . THR C 3 164 ? -7.006  -60.507 -26.573 1.00 67.42  ? 160 THR C N   1 
ATOM   4510 C CA  . THR C 3 164 ? -6.827  -61.092 -25.252 1.00 81.61  ? 160 THR C CA  1 
ATOM   4511 C C   . THR C 3 164 ? -6.407  -60.003 -24.267 1.00 85.74  ? 160 THR C C   1 
ATOM   4512 O O   . THR C 3 164 ? -6.025  -58.906 -24.674 1.00 84.99  ? 160 THR C O   1 
ATOM   4513 C CB  . THR C 3 164 ? -5.771  -62.218 -25.277 1.00 74.90  ? 160 THR C CB  1 
ATOM   4514 O OG1 . THR C 3 164 ? -5.854  -62.922 -26.523 1.00 59.68  ? 160 THR C OG1 1 
ATOM   4515 C CG2 . THR C 3 164 ? -6.000  -63.207 -24.141 1.00 68.00  ? 160 THR C CG2 1 
ATOM   4516 N N   . SER C 3 165 ? -6.492  -60.302 -22.976 1.00 99.33  ? 161 SER C N   1 
ATOM   4517 C CA  . SER C 3 165 ? -6.021  -59.411 -21.928 1.00 86.81  ? 161 SER C CA  1 
ATOM   4518 C C   . SER C 3 165 ? -4.708  -59.936 -21.362 1.00 81.37  ? 161 SER C C   1 
ATOM   4519 O O   . SER C 3 165 ? -4.309  -61.079 -21.604 1.00 88.43  ? 161 SER C O   1 
ATOM   4520 C CB  . SER C 3 165 ? -7.067  -59.264 -20.818 1.00 80.23  ? 161 SER C CB  1 
ATOM   4521 O OG  . SER C 3 165 ? -7.279  -60.493 -20.148 1.00 81.69  ? 161 SER C OG  1 
ATOM   4522 N N   . GLY C 3 166 ? -4.037  -59.085 -20.592 1.00 81.98  ? 162 GLY C N   1 
ATOM   4523 C CA  . GLY C 3 166 ? -2.714  -59.419 -20.108 1.00 92.50  ? 162 GLY C CA  1 
ATOM   4524 C C   . GLY C 3 166 ? -1.629  -59.274 -21.150 1.00 81.30  ? 162 GLY C C   1 
ATOM   4525 O O   . GLY C 3 166 ? -0.593  -59.939 -21.054 1.00 68.69  ? 162 GLY C O   1 
ATOM   4526 N N   . VAL C 3 167 ? -1.843  -58.424 -22.149 1.00 82.15  ? 163 VAL C N   1 
ATOM   4527 C CA  . VAL C 3 167 ? -0.888  -58.209 -23.228 1.00 68.86  ? 163 VAL C CA  1 
ATOM   4528 C C   . VAL C 3 167 ? -0.183  -56.881 -23.001 1.00 67.95  ? 163 VAL C C   1 
ATOM   4529 O O   . VAL C 3 167 ? -0.719  -55.965 -22.366 1.00 63.97  ? 163 VAL C O   1 
ATOM   4530 C CB  . VAL C 3 167 ? -1.582  -58.243 -24.607 1.00 75.24  ? 163 VAL C CB  1 
ATOM   4531 C CG1 . VAL C 3 167 ? -2.407  -59.510 -24.755 1.00 75.65  ? 163 VAL C CG1 1 
ATOM   4532 C CG2 . VAL C 3 167 ? -2.454  -57.011 -24.802 1.00 61.22  ? 163 VAL C CG2 1 
ATOM   4533 N N   . HIS C 3 168 ? 1.041   -56.778 -23.516 1.00 69.60  ? 164 HIS C N   1 
ATOM   4534 C CA  . HIS C 3 168 ? 1.832   -55.554 -23.427 1.00 63.52  ? 164 HIS C CA  1 
ATOM   4535 C C   . HIS C 3 168 ? 2.390   -55.240 -24.808 1.00 52.02  ? 164 HIS C C   1 
ATOM   4536 O O   . HIS C 3 168 ? 3.264   -55.957 -25.306 1.00 55.06  ? 164 HIS C O   1 
ATOM   4537 C CB  . HIS C 3 168 ? 2.959   -55.694 -22.402 1.00 62.92  ? 164 HIS C CB  1 
ATOM   4538 C CG  . HIS C 3 168 ? 2.483   -55.994 -21.015 1.00 61.31  ? 164 HIS C CG  1 
ATOM   4539 N ND1 . HIS C 3 168 ? 2.735   -57.194 -20.386 1.00 67.98  ? 164 HIS C ND1 1 
ATOM   4540 C CD2 . HIS C 3 168 ? 1.770   -55.251 -20.136 1.00 59.65  ? 164 HIS C CD2 1 
ATOM   4541 C CE1 . HIS C 3 168 ? 2.199   -57.177 -19.178 1.00 69.34  ? 164 HIS C CE1 1 
ATOM   4542 N NE2 . HIS C 3 168 ? 1.607   -56.010 -19.002 1.00 86.04  ? 164 HIS C NE2 1 
ATOM   4543 N N   . THR C 3 169 ? 1.884   -54.174 -25.425 1.00 49.82  ? 165 THR C N   1 
ATOM   4544 C CA  . THR C 3 169 ? 2.399   -53.677 -26.696 1.00 53.87  ? 165 THR C CA  1 
ATOM   4545 C C   . THR C 3 169 ? 3.334   -52.511 -26.397 1.00 55.12  ? 165 THR C C   1 
ATOM   4546 O O   . THR C 3 169 ? 2.883   -51.426 -26.015 1.00 51.68  ? 165 THR C O   1 
ATOM   4547 C CB  . THR C 3 169 ? 1.264   -53.251 -27.625 1.00 40.28  ? 165 THR C CB  1 
ATOM   4548 O OG1 . THR C 3 169 ? 0.491   -54.399 -27.996 1.00 58.63  ? 165 THR C OG1 1 
ATOM   4549 C CG2 . THR C 3 169 ? 1.821   -52.591 -28.880 1.00 35.32  ? 165 THR C CG2 1 
ATOM   4550 N N   . PHE C 3 170 ? 4.633   -52.739 -26.566 1.00 49.90  ? 166 PHE C N   1 
ATOM   4551 C CA  . PHE C 3 170 ? 5.619   -51.740 -26.196 1.00 52.74  ? 166 PHE C CA  1 
ATOM   4552 C C   . PHE C 3 170 ? 5.556   -50.538 -27.137 1.00 45.69  ? 166 PHE C C   1 
ATOM   4553 O O   . PHE C 3 170 ? 5.160   -50.667 -28.299 1.00 42.57  ? 166 PHE C O   1 
ATOM   4554 C CB  . PHE C 3 170 ? 7.021   -52.341 -26.216 1.00 50.15  ? 166 PHE C CB  1 
ATOM   4555 C CG  . PHE C 3 170 ? 7.205   -53.469 -25.247 1.00 43.39  ? 166 PHE C CG  1 
ATOM   4556 C CD1 . PHE C 3 170 ? 7.379   -53.216 -23.898 1.00 40.87  ? 166 PHE C CD1 1 
ATOM   4557 C CD2 . PHE C 3 170 ? 7.205   -54.782 -25.684 1.00 41.86  ? 166 PHE C CD2 1 
ATOM   4558 C CE1 . PHE C 3 170 ? 7.545   -54.250 -23.001 1.00 51.40  ? 166 PHE C CE1 1 
ATOM   4559 C CE2 . PHE C 3 170 ? 7.373   -55.821 -24.791 1.00 57.13  ? 166 PHE C CE2 1 
ATOM   4560 C CZ  . PHE C 3 170 ? 7.543   -55.554 -23.449 1.00 59.44  ? 166 PHE C CZ  1 
ATOM   4561 N N   . PRO C 3 171 ? 5.920   -49.353 -26.648 1.00 51.76  ? 167 PRO C N   1 
ATOM   4562 C CA  . PRO C 3 171 ? 6.003   -48.187 -27.534 1.00 46.85  ? 167 PRO C CA  1 
ATOM   4563 C C   . PRO C 3 171 ? 7.017   -48.411 -28.645 1.00 42.44  ? 167 PRO C C   1 
ATOM   4564 O O   . PRO C 3 171 ? 8.062   -49.034 -28.444 1.00 60.56  ? 167 PRO C O   1 
ATOM   4565 C CB  . PRO C 3 171 ? 6.439   -47.058 -26.594 1.00 35.14  ? 167 PRO C CB  1 
ATOM   4566 C CG  . PRO C 3 171 ? 5.993   -47.502 -25.240 1.00 47.94  ? 167 PRO C CG  1 
ATOM   4567 C CD  . PRO C 3 171 ? 6.133   -48.995 -25.236 1.00 48.97  ? 167 PRO C CD  1 
ATOM   4568 N N   . ALA C 3 172 ? 6.696   -47.895 -29.828 1.00 44.60  ? 168 ALA C N   1 
ATOM   4569 C CA  . ALA C 3 172 ? 7.589   -48.033 -30.968 1.00 49.31  ? 168 ALA C CA  1 
ATOM   4570 C C   . ALA C 3 172 ? 8.870   -47.240 -30.745 1.00 50.00  ? 168 ALA C C   1 
ATOM   4571 O O   . ALA C 3 172 ? 8.852   -46.142 -30.180 1.00 53.48  ? 168 ALA C O   1 
ATOM   4572 C CB  . ALA C 3 172 ? 6.897   -47.564 -32.245 1.00 53.49  ? 168 ALA C CB  1 
ATOM   4573 N N   . VAL C 3 173 ? 9.987   -47.805 -31.194 1.00 57.51  ? 169 VAL C N   1 
ATOM   4574 C CA  . VAL C 3 173 ? 11.302  -47.191 -31.060 1.00 53.35  ? 169 VAL C CA  1 
ATOM   4575 C C   . VAL C 3 173 ? 11.862  -46.959 -32.455 1.00 47.93  ? 169 VAL C C   1 
ATOM   4576 O O   . VAL C 3 173 ? 11.836  -47.864 -33.297 1.00 42.97  ? 169 VAL C O   1 
ATOM   4577 C CB  . VAL C 3 173 ? 12.259  -48.066 -30.229 1.00 45.12  ? 169 VAL C CB  1 
ATOM   4578 C CG1 . VAL C 3 173 ? 13.458  -47.250 -29.766 1.00 40.61  ? 169 VAL C CG1 1 
ATOM   4579 C CG2 . VAL C 3 173 ? 11.529  -48.681 -29.047 1.00 45.13  ? 169 VAL C CG2 1 
ATOM   4580 N N   . LEU C 3 174 ? 12.355  -45.748 -32.700 1.00 54.83  ? 170 LEU C N   1 
ATOM   4581 C CA  . LEU C 3 174 ? 12.972  -45.424 -33.978 1.00 41.82  ? 170 LEU C CA  1 
ATOM   4582 C C   . LEU C 3 174 ? 14.359  -46.050 -34.051 1.00 50.80  ? 170 LEU C C   1 
ATOM   4583 O O   . LEU C 3 174 ? 15.188  -45.852 -33.158 1.00 54.67  ? 170 LEU C O   1 
ATOM   4584 C CB  . LEU C 3 174 ? 13.062  -43.910 -34.161 1.00 47.06  ? 170 LEU C CB  1 
ATOM   4585 C CG  . LEU C 3 174 ? 13.471  -43.436 -35.558 1.00 43.59  ? 170 LEU C CG  1 
ATOM   4586 C CD1 . LEU C 3 174 ? 12.399  -43.791 -36.579 1.00 46.83  ? 170 LEU C CD1 1 
ATOM   4587 C CD2 . LEU C 3 174 ? 13.757  -41.942 -35.568 1.00 35.00  ? 170 LEU C CD2 1 
ATOM   4588 N N   . GLN C 3 175 ? 14.606  -46.804 -35.117 1.00 58.18  ? 171 GLN C N   1 
ATOM   4589 C CA  . GLN C 3 175 ? 15.872  -47.493 -35.299 1.00 50.78  ? 171 GLN C CA  1 
ATOM   4590 C C   . GLN C 3 175 ? 16.866  -46.598 -36.034 1.00 50.21  ? 171 GLN C C   1 
ATOM   4591 O O   . GLN C 3 175 ? 16.526  -45.533 -36.555 1.00 46.28  ? 171 GLN C O   1 
ATOM   4592 C CB  . GLN C 3 175 ? 15.666  -48.804 -36.059 1.00 43.33  ? 171 GLN C CB  1 
ATOM   4593 C CG  . GLN C 3 175 ? 14.788  -49.811 -35.332 1.00 41.47  ? 171 GLN C CG  1 
ATOM   4594 C CD  . GLN C 3 175 ? 14.527  -51.057 -36.158 1.00 47.26  ? 171 GLN C CD  1 
ATOM   4595 O OE1 . GLN C 3 175 ? 14.819  -52.174 -35.728 1.00 42.18  ? 171 GLN C OE1 1 
ATOM   4596 N NE2 . GLN C 3 175 ? 13.971  -50.870 -37.350 1.00 47.00  ? 171 GLN C NE2 1 
ATOM   4597 N N   . SER C 3 176 ? 18.123  -47.051 -36.066 1.00 57.08  ? 172 SER C N   1 
ATOM   4598 C CA  . SER C 3 176 ? 19.172  -46.276 -36.719 1.00 56.90  ? 172 SER C CA  1 
ATOM   4599 C C   . SER C 3 176 ? 18.922  -46.139 -38.215 1.00 43.94  ? 172 SER C C   1 
ATOM   4600 O O   . SER C 3 176 ? 19.392  -45.179 -38.838 1.00 44.69  ? 172 SER C O   1 
ATOM   4601 C CB  . SER C 3 176 ? 20.537  -46.915 -36.461 1.00 46.27  ? 172 SER C CB  1 
ATOM   4602 O OG  . SER C 3 176 ? 20.561  -48.255 -36.916 1.00 54.05  ? 172 SER C OG  1 
ATOM   4603 N N   . SER C 3 177 ? 18.190  -47.082 -38.808 1.00 38.59  ? 173 SER C N   1 
ATOM   4604 C CA  . SER C 3 177 ? 17.844  -46.988 -40.220 1.00 37.93  ? 173 SER C CA  1 
ATOM   4605 C C   . SER C 3 177 ? 16.783  -45.931 -40.498 1.00 45.35  ? 173 SER C C   1 
ATOM   4606 O O   . SER C 3 177 ? 16.563  -45.591 -41.666 1.00 43.26  ? 173 SER C O   1 
ATOM   4607 C CB  . SER C 3 177 ? 17.364  -48.347 -40.735 1.00 40.55  ? 173 SER C CB  1 
ATOM   4608 O OG  . SER C 3 177 ? 16.189  -48.762 -40.061 1.00 47.50  ? 173 SER C OG  1 
ATOM   4609 N N   . GLY C 3 178 ? 16.137  -45.397 -39.465 1.00 49.08  ? 174 GLY C N   1 
ATOM   4610 C CA  . GLY C 3 178 ? 15.050  -44.460 -39.645 1.00 47.01  ? 174 GLY C CA  1 
ATOM   4611 C C   . GLY C 3 178 ? 13.673  -45.080 -39.708 1.00 49.53  ? 174 GLY C C   1 
ATOM   4612 O O   . GLY C 3 178 ? 12.711  -44.377 -40.038 1.00 47.85  ? 174 GLY C O   1 
ATOM   4613 N N   . LEU C 3 179 ? 13.547  -46.369 -39.405 1.00 43.76  ? 175 LEU C N   1 
ATOM   4614 C CA  . LEU C 3 179 ? 12.273  -47.072 -39.437 1.00 49.85  ? 175 LEU C CA  1 
ATOM   4615 C C   . LEU C 3 179 ? 11.909  -47.531 -38.033 1.00 42.01  ? 175 LEU C C   1 
ATOM   4616 O O   . LEU C 3 179 ? 12.773  -47.975 -37.270 1.00 48.70  ? 175 LEU C O   1 
ATOM   4617 C CB  . LEU C 3 179 ? 12.328  -48.278 -40.382 1.00 54.53  ? 175 LEU C CB  1 
ATOM   4618 C CG  . LEU C 3 179 ? 12.872  -48.025 -41.790 1.00 47.83  ? 175 LEU C CG  1 
ATOM   4619 C CD1 . LEU C 3 179 ? 12.767  -49.284 -42.639 1.00 59.09  ? 175 LEU C CD1 1 
ATOM   4620 C CD2 . LEU C 3 179 ? 12.152  -46.861 -42.454 1.00 45.92  ? 175 LEU C CD2 1 
ATOM   4621 N N   . TYR C 3 180 ? 10.627  -47.428 -37.698 1.00 39.80  ? 176 TYR C N   1 
ATOM   4622 C CA  . TYR C 3 180 ? 10.162  -47.796 -36.372 1.00 45.63  ? 176 TYR C CA  1 
ATOM   4623 C C   . TYR C 3 180 ? 10.085  -49.314 -36.223 1.00 41.58  ? 176 TYR C C   1 
ATOM   4624 O O   . TYR C 3 180 ? 10.070  -50.066 -37.201 1.00 52.08  ? 176 TYR C O   1 
ATOM   4625 C CB  . TYR C 3 180 ? 8.798   -47.170 -36.087 1.00 47.09  ? 176 TYR C CB  1 
ATOM   4626 C CG  . TYR C 3 180 ? 8.834   -45.662 -35.999 1.00 50.47  ? 176 TYR C CG  1 
ATOM   4627 C CD1 . TYR C 3 180 ? 9.062   -45.025 -34.787 1.00 53.87  ? 176 TYR C CD1 1 
ATOM   4628 C CD2 . TYR C 3 180 ? 8.647   -44.877 -37.128 1.00 52.02  ? 176 TYR C CD2 1 
ATOM   4629 C CE1 . TYR C 3 180 ? 9.100   -43.646 -34.701 1.00 48.91  ? 176 TYR C CE1 1 
ATOM   4630 C CE2 . TYR C 3 180 ? 8.683   -43.497 -37.052 1.00 57.25  ? 176 TYR C CE2 1 
ATOM   4631 C CZ  . TYR C 3 180 ? 8.909   -42.888 -35.836 1.00 53.76  ? 176 TYR C CZ  1 
ATOM   4632 O OH  . TYR C 3 180 ? 8.946   -41.515 -35.755 1.00 48.83  ? 176 TYR C OH  1 
ATOM   4633 N N   . SER C 3 181 ? 10.047  -49.755 -34.968 1.00 36.90  ? 177 SER C N   1 
ATOM   4634 C CA  . SER C 3 181 ? 9.926   -51.168 -34.646 1.00 43.72  ? 177 SER C CA  1 
ATOM   4635 C C   . SER C 3 181 ? 9.311   -51.297 -33.261 1.00 51.15  ? 177 SER C C   1 
ATOM   4636 O O   . SER C 3 181 ? 9.515   -50.441 -32.396 1.00 51.40  ? 177 SER C O   1 
ATOM   4637 C CB  . SER C 3 181 ? 11.283  -51.879 -34.700 1.00 38.91  ? 177 SER C CB  1 
ATOM   4638 O OG  . SER C 3 181 ? 11.146  -53.260 -34.416 1.00 44.81  ? 177 SER C OG  1 
ATOM   4639 N N   . LEU C 3 182 ? 8.556   -52.374 -33.060 1.00 44.38  ? 178 LEU C N   1 
ATOM   4640 C CA  . LEU C 3 182 ? 7.903   -52.614 -31.781 1.00 45.35  ? 178 LEU C CA  1 
ATOM   4641 C C   . LEU C 3 182 ? 7.628   -54.104 -31.645 1.00 45.59  ? 178 LEU C C   1 
ATOM   4642 O O   . LEU C 3 182 ? 7.689   -54.861 -32.616 1.00 50.83  ? 178 LEU C O   1 
ATOM   4643 C CB  . LEU C 3 182 ? 6.608   -51.801 -31.648 1.00 46.79  ? 178 LEU C CB  1 
ATOM   4644 C CG  . LEU C 3 182 ? 5.370   -52.246 -32.435 1.00 48.76  ? 178 LEU C CG  1 
ATOM   4645 C CD1 . LEU C 3 182 ? 4.462   -53.143 -31.600 1.00 48.72  ? 178 LEU C CD1 1 
ATOM   4646 C CD2 . LEU C 3 182 ? 4.597   -51.043 -32.945 1.00 49.36  ? 178 LEU C CD2 1 
ATOM   4647 N N   . SER C 3 183 ? 7.321   -54.513 -30.416 1.00 47.59  ? 179 SER C N   1 
ATOM   4648 C CA  . SER C 3 183 ? 6.941   -55.883 -30.112 1.00 51.36  ? 179 SER C CA  1 
ATOM   4649 C C   . SER C 3 183 ? 5.695   -55.880 -29.240 1.00 56.53  ? 179 SER C C   1 
ATOM   4650 O O   . SER C 3 183 ? 5.516   -54.991 -28.402 1.00 62.98  ? 179 SER C O   1 
ATOM   4651 C CB  . SER C 3 183 ? 8.072   -56.636 -29.400 1.00 59.88  ? 179 SER C CB  1 
ATOM   4652 O OG  . SER C 3 183 ? 9.227   -56.717 -30.217 1.00 74.81  ? 179 SER C OG  1 
ATOM   4653 N N   . SER C 3 184 ? 4.835   -56.871 -29.450 1.00 49.78  ? 180 SER C N   1 
ATOM   4654 C CA  . SER C 3 184 ? 3.678   -57.116 -28.600 1.00 56.20  ? 180 SER C CA  1 
ATOM   4655 C C   . SER C 3 184 ? 3.842   -58.481 -27.955 1.00 61.83  ? 180 SER C C   1 
ATOM   4656 O O   . SER C 3 184 ? 4.165   -59.456 -28.639 1.00 60.48  ? 180 SER C O   1 
ATOM   4657 C CB  . SER C 3 184 ? 2.371   -57.055 -29.396 1.00 63.33  ? 180 SER C CB  1 
ATOM   4658 O OG  . SER C 3 184 ? 2.040   -55.721 -29.737 1.00 67.61  ? 180 SER C OG  1 
ATOM   4659 N N   . VAL C 3 185 ? 3.632   -58.549 -26.642 1.00 64.02  ? 181 VAL C N   1 
ATOM   4660 C CA  . VAL C 3 185 ? 3.797   -59.786 -25.894 1.00 66.01  ? 181 VAL C CA  1 
ATOM   4661 C C   . VAL C 3 185 ? 2.481   -60.126 -25.209 1.00 69.63  ? 181 VAL C C   1 
ATOM   4662 O O   . VAL C 3 185 ? 1.610   -59.274 -25.017 1.00 69.56  ? 181 VAL C O   1 
ATOM   4663 C CB  . VAL C 3 185 ? 4.938   -59.698 -24.857 1.00 71.87  ? 181 VAL C CB  1 
ATOM   4664 C CG1 . VAL C 3 185 ? 6.175   -59.062 -25.472 1.00 50.02  ? 181 VAL C CG1 1 
ATOM   4665 C CG2 . VAL C 3 185 ? 4.484   -58.929 -23.622 1.00 66.52  ? 181 VAL C CG2 1 
ATOM   4666 N N   . VAL C 3 186 ? 2.343   -61.398 -24.851 1.00 78.89  ? 182 VAL C N   1 
ATOM   4667 C CA  . VAL C 3 186 ? 1.202   -61.870 -24.071 1.00 86.44  ? 182 VAL C CA  1 
ATOM   4668 C C   . VAL C 3 186 ? 1.651   -63.072 -23.252 1.00 93.06  ? 182 VAL C C   1 
ATOM   4669 O O   . VAL C 3 186 ? 2.337   -63.963 -23.762 1.00 94.35  ? 182 VAL C O   1 
ATOM   4670 C CB  . VAL C 3 186 ? -0.007  -62.220 -24.965 1.00 82.49  ? 182 VAL C CB  1 
ATOM   4671 C CG1 . VAL C 3 186 ? 0.411   -63.124 -26.110 1.00 67.34  ? 182 VAL C CG1 1 
ATOM   4672 C CG2 . VAL C 3 186 ? -1.114  -62.868 -24.143 1.00 90.36  ? 182 VAL C CG2 1 
ATOM   4673 N N   . THR C 3 187 ? 1.278   -63.085 -21.976 1.00 78.26  ? 183 THR C N   1 
ATOM   4674 C CA  . THR C 3 187 ? 1.607   -64.184 -21.079 1.00 85.12  ? 183 THR C CA  1 
ATOM   4675 C C   . THR C 3 187 ? 0.457   -65.183 -21.080 1.00 89.43  ? 183 THR C C   1 
ATOM   4676 O O   . THR C 3 187 ? -0.679  -64.830 -20.745 1.00 90.21  ? 183 THR C O   1 
ATOM   4677 C CB  . THR C 3 187 ? 1.877   -63.664 -19.668 1.00 89.31  ? 183 THR C CB  1 
ATOM   4678 O OG1 . THR C 3 187 ? 0.764   -62.877 -19.227 1.00 79.23  ? 183 THR C OG1 1 
ATOM   4679 C CG2 . THR C 3 187 ? 3.134   -62.805 -19.650 1.00 77.86  ? 183 THR C CG2 1 
ATOM   4680 N N   . VAL C 3 188 ? 0.751   -66.424 -21.457 1.00 91.52  ? 184 VAL C N   1 
ATOM   4681 C CA  . VAL C 3 188 ? -0.278  -67.451 -21.604 1.00 92.37  ? 184 VAL C CA  1 
ATOM   4682 C C   . VAL C 3 188 ? 0.119   -68.660 -20.768 1.00 104.67 ? 184 VAL C C   1 
ATOM   4683 O O   . VAL C 3 188 ? 1.303   -68.853 -20.447 1.00 107.68 ? 184 VAL C O   1 
ATOM   4684 C CB  . VAL C 3 188 ? -0.480  -67.850 -23.086 1.00 90.73  ? 184 VAL C CB  1 
ATOM   4685 C CG1 . VAL C 3 188 ? -0.677  -66.615 -23.954 1.00 90.00  ? 184 VAL C CG1 1 
ATOM   4686 C CG2 . VAL C 3 188 ? 0.693   -68.683 -23.581 1.00 92.94  ? 184 VAL C CG2 1 
ATOM   4687 N N   . PRO C 3 189 ? -0.855  -69.481 -20.373 1.00 104.51 ? 185 PRO C N   1 
ATOM   4688 C CA  . PRO C 3 189 ? -0.522  -70.730 -19.678 1.00 102.18 ? 185 PRO C CA  1 
ATOM   4689 C C   . PRO C 3 189 ? 0.329   -71.641 -20.552 1.00 100.02 ? 185 PRO C C   1 
ATOM   4690 O O   . PRO C 3 189 ? 0.134   -71.730 -21.766 1.00 92.48  ? 185 PRO C O   1 
ATOM   4691 C CB  . PRO C 3 189 ? -1.894  -71.348 -19.386 1.00 108.48 ? 185 PRO C CB  1 
ATOM   4692 C CG  . PRO C 3 189 ? -2.829  -70.185 -19.360 1.00 103.14 ? 185 PRO C CG  1 
ATOM   4693 C CD  . PRO C 3 189 ? -2.306  -69.227 -20.389 1.00 101.90 ? 185 PRO C CD  1 
ATOM   4694 N N   . SER C 3 190 ? 1.281   -72.327 -19.915 1.00 108.91 ? 186 SER C N   1 
ATOM   4695 C CA  . SER C 3 190 ? 2.194   -73.191 -20.656 1.00 116.24 ? 186 SER C CA  1 
ATOM   4696 C C   . SER C 3 190 ? 1.508   -74.462 -21.139 1.00 123.95 ? 186 SER C C   1 
ATOM   4697 O O   . SER C 3 190 ? 1.852   -74.982 -22.207 1.00 111.87 ? 186 SER C O   1 
ATOM   4698 C CB  . SER C 3 190 ? 3.404   -73.541 -19.790 1.00 95.56  ? 186 SER C CB  1 
ATOM   4699 O OG  . SER C 3 190 ? 3.013   -74.279 -18.645 1.00 93.43  ? 186 SER C OG  1 
ATOM   4700 N N   . SER C 3 191 ? 0.546   -74.974 -20.377 1.00 129.17 ? 187 SER C N   1 
ATOM   4701 C CA  . SER C 3 191 ? -0.154  -76.216 -20.703 1.00 127.77 ? 187 SER C CA  1 
ATOM   4702 C C   . SER C 3 191 ? -1.153  -76.064 -21.847 1.00 129.52 ? 187 SER C C   1 
ATOM   4703 O O   . SER C 3 191 ? -1.915  -77.010 -22.092 1.00 126.30 ? 187 SER C O   1 
ATOM   4704 C CB  . SER C 3 191 ? -0.867  -76.747 -19.458 1.00 132.06 ? 187 SER C CB  1 
ATOM   4705 O OG  . SER C 3 191 ? -1.721  -75.763 -18.902 1.00 116.87 ? 187 SER C OG  1 
ATOM   4706 N N   . SER C 3 192 ? -1.181  -74.936 -22.550 1.00 124.81 ? 188 SER C N   1 
ATOM   4707 C CA  . SER C 3 192 ? -2.142  -74.683 -23.619 1.00 119.99 ? 188 SER C CA  1 
ATOM   4708 C C   . SER C 3 192 ? -1.429  -74.189 -24.872 1.00 114.79 ? 188 SER C C   1 
ATOM   4709 O O   . SER C 3 192 ? -1.824  -73.202 -25.495 1.00 108.44 ? 188 SER C O   1 
ATOM   4710 C CB  . SER C 3 192 ? -3.198  -73.679 -23.164 1.00 105.66 ? 188 SER C CB  1 
ATOM   4711 O OG  . SER C 3 192 ? -3.824  -74.107 -21.967 1.00 109.99 ? 188 SER C OG  1 
ATOM   4712 N N   . LEU C 3 193 ? -0.355  -74.878 -25.263 1.00 111.81 ? 189 LEU C N   1 
ATOM   4713 C CA  . LEU C 3 193 ? 0.394   -74.452 -26.442 1.00 115.81 ? 189 LEU C CA  1 
ATOM   4714 C C   . LEU C 3 193 ? -0.349  -74.800 -27.729 1.00 122.89 ? 189 LEU C C   1 
ATOM   4715 O O   . LEU C 3 193 ? -0.595  -73.926 -28.569 1.00 115.90 ? 189 LEU C O   1 
ATOM   4716 C CB  . LEU C 3 193 ? 1.800   -75.064 -26.431 1.00 102.46 ? 189 LEU C CB  1 
ATOM   4717 C CG  . LEU C 3 193 ? 2.055   -76.549 -26.145 1.00 104.00 ? 189 LEU C CG  1 
ATOM   4718 C CD1 . LEU C 3 193 ? 2.053   -77.383 -27.418 1.00 89.27  ? 189 LEU C CD1 1 
ATOM   4719 C CD2 . LEU C 3 193 ? 3.375   -76.721 -25.410 1.00 67.72  ? 189 LEU C CD2 1 
ATOM   4720 N N   . GLY C 3 194 ? -0.722  -76.065 -27.900 1.00 120.02 ? 190 GLY C N   1 
ATOM   4721 C CA  . GLY C 3 194 ? -1.355  -76.497 -29.131 1.00 114.87 ? 190 GLY C CA  1 
ATOM   4722 C C   . GLY C 3 194 ? -2.866  -76.526 -29.060 1.00 119.13 ? 190 GLY C C   1 
ATOM   4723 O O   . GLY C 3 194 ? -3.543  -76.613 -30.090 1.00 116.47 ? 190 GLY C O   1 
ATOM   4724 N N   . THR C 3 195 ? -3.407  -76.464 -27.841 1.00 114.41 ? 191 THR C N   1 
ATOM   4725 C CA  . THR C 3 195 ? -4.857  -76.435 -27.681 1.00 109.75 ? 191 THR C CA  1 
ATOM   4726 C C   . THR C 3 195 ? -5.445  -75.167 -28.284 1.00 110.12 ? 191 THR C C   1 
ATOM   4727 O O   . THR C 3 195 ? -6.490  -75.209 -28.944 1.00 112.49 ? 191 THR C O   1 
ATOM   4728 C CB  . THR C 3 195 ? -5.230  -76.546 -26.202 1.00 112.06 ? 191 THR C CB  1 
ATOM   4729 O OG1 . THR C 3 195 ? -4.817  -75.360 -25.511 1.00 122.86 ? 191 THR C OG1 1 
ATOM   4730 C CG2 . THR C 3 195 ? -4.556  -77.755 -25.567 1.00 110.63 ? 191 THR C CG2 1 
ATOM   4731 N N   . GLN C 3 196 ? -4.784  -74.033 -28.072 1.00 112.50 ? 192 GLN C N   1 
ATOM   4732 C CA  . GLN C 3 196 ? -5.217  -72.746 -28.596 1.00 108.35 ? 192 GLN C CA  1 
ATOM   4733 C C   . GLN C 3 196 ? -4.177  -72.244 -29.586 1.00 106.63 ? 192 GLN C C   1 
ATOM   4734 O O   . GLN C 3 196 ? -2.985  -72.191 -29.265 1.00 108.34 ? 192 GLN C O   1 
ATOM   4735 C CB  . GLN C 3 196 ? -5.412  -71.732 -27.464 1.00 93.84  ? 192 GLN C CB  1 
ATOM   4736 C CG  . GLN C 3 196 ? -6.686  -70.908 -27.567 1.00 86.83  ? 192 GLN C CG  1 
ATOM   4737 C CD  . GLN C 3 196 ? -6.652  -69.903 -28.702 1.00 100.60 ? 192 GLN C CD  1 
ATOM   4738 O OE1 . GLN C 3 196 ? -5.585  -69.540 -29.195 1.00 99.49  ? 192 GLN C OE1 1 
ATOM   4739 N NE2 . GLN C 3 196 ? -7.827  -69.447 -29.121 1.00 97.05  ? 192 GLN C NE2 1 
ATOM   4740 N N   . THR C 3 197 ? -4.625  -71.884 -30.786 1.00 100.41 ? 193 THR C N   1 
ATOM   4741 C CA  . THR C 3 197 ? -3.741  -71.336 -31.809 1.00 108.51 ? 193 THR C CA  1 
ATOM   4742 C C   . THR C 3 197 ? -3.720  -69.816 -31.663 1.00 112.22 ? 193 THR C C   1 
ATOM   4743 O O   . THR C 3 197 ? -4.732  -69.145 -31.889 1.00 92.69  ? 193 THR C O   1 
ATOM   4744 C CB  . THR C 3 197 ? -4.190  -71.768 -33.206 1.00 93.80  ? 193 THR C CB  1 
ATOM   4745 O OG1 . THR C 3 197 ? -3.523  -70.975 -34.196 1.00 103.07 ? 193 THR C OG1 1 
ATOM   4746 C CG2 . THR C 3 197 ? -5.703  -71.638 -33.368 1.00 75.68  ? 193 THR C CG2 1 
ATOM   4747 N N   . TYR C 3 198 ? -2.568  -69.276 -31.272 1.00 114.92 ? 194 TYR C N   1 
ATOM   4748 C CA  . TYR C 3 198 ? -2.435  -67.852 -30.995 1.00 99.04  ? 194 TYR C CA  1 
ATOM   4749 C C   . TYR C 3 198 ? -2.011  -67.108 -32.255 1.00 93.74  ? 194 TYR C C   1 
ATOM   4750 O O   . TYR C 3 198 ? -1.063  -67.511 -32.936 1.00 84.19  ? 194 TYR C O   1 
ATOM   4751 C CB  . TYR C 3 198 ? -1.426  -67.613 -29.872 1.00 89.42  ? 194 TYR C CB  1 
ATOM   4752 C CG  . TYR C 3 198 ? -1.917  -68.029 -28.503 1.00 82.52  ? 194 TYR C CG  1 
ATOM   4753 C CD1 . TYR C 3 198 ? -2.665  -67.160 -27.720 1.00 77.93  ? 194 TYR C CD1 1 
ATOM   4754 C CD2 . TYR C 3 198 ? -1.627  -69.288 -27.990 1.00 89.60  ? 194 TYR C CD2 1 
ATOM   4755 C CE1 . TYR C 3 198 ? -3.115  -67.533 -26.468 1.00 82.52  ? 194 TYR C CE1 1 
ATOM   4756 C CE2 . TYR C 3 198 ? -2.073  -69.670 -26.737 1.00 87.47  ? 194 TYR C CE2 1 
ATOM   4757 C CZ  . TYR C 3 198 ? -2.816  -68.788 -25.981 1.00 86.27  ? 194 TYR C CZ  1 
ATOM   4758 O OH  . TYR C 3 198 ? -3.263  -69.162 -24.734 1.00 77.82  ? 194 TYR C OH  1 
ATOM   4759 N N   . ILE C 3 199 ? -2.718  -66.021 -32.558 1.00 88.26  ? 195 ILE C N   1 
ATOM   4760 C CA  . ILE C 3 199 ? -2.482  -65.229 -33.760 1.00 90.13  ? 195 ILE C CA  1 
ATOM   4761 C C   . ILE C 3 199 ? -2.502  -63.753 -33.387 1.00 90.98  ? 195 ILE C C   1 
ATOM   4762 O O   . ILE C 3 199 ? -3.318  -63.319 -32.566 1.00 84.66  ? 195 ILE C O   1 
ATOM   4763 C CB  . ILE C 3 199 ? -3.529  -65.537 -34.851 1.00 89.49  ? 195 ILE C CB  1 
ATOM   4764 C CG1 . ILE C 3 199 ? -4.930  -65.589 -34.238 1.00 97.43  ? 195 ILE C CG1 1 
ATOM   4765 C CG2 . ILE C 3 199 ? -3.198  -66.844 -35.555 1.00 81.86  ? 195 ILE C CG2 1 
ATOM   4766 C CD1 . ILE C 3 199 ? -5.994  -66.114 -35.177 1.00 84.81  ? 195 ILE C CD1 1 
ATOM   4767 N N   . CYS C 3 200 ? -1.602  -62.982 -33.991 1.00 87.59  ? 196 CYS C N   1 
ATOM   4768 C CA  . CYS C 3 200 ? -1.492  -61.550 -33.746 1.00 79.99  ? 196 CYS C CA  1 
ATOM   4769 C C   . CYS C 3 200 ? -1.929  -60.785 -34.988 1.00 75.72  ? 196 CYS C C   1 
ATOM   4770 O O   . CYS C 3 200 ? -1.483  -61.089 -36.099 1.00 82.41  ? 196 CYS C O   1 
ATOM   4771 C CB  . CYS C 3 200 ? -0.061  -61.165 -33.357 1.00 91.17  ? 196 CYS C CB  1 
ATOM   4772 S SG  . CYS C 3 200 ? 1.210   -61.565 -34.592 1.00 109.40 ? 196 CYS C SG  1 
ATOM   4773 N N   . ASN C 3 201 ? -2.801  -59.798 -34.794 1.00 75.73  ? 197 ASN C N   1 
ATOM   4774 C CA  . ASN C 3 201 ? -3.290  -58.946 -35.872 1.00 76.91  ? 197 ASN C CA  1 
ATOM   4775 C C   . ASN C 3 201 ? -2.514  -57.638 -35.849 1.00 70.63  ? 197 ASN C C   1 
ATOM   4776 O O   . ASN C 3 201 ? -2.537  -56.921 -34.845 1.00 66.85  ? 197 ASN C O   1 
ATOM   4777 C CB  . ASN C 3 201 ? -4.786  -58.664 -35.727 1.00 80.89  ? 197 ASN C CB  1 
ATOM   4778 C CG  . ASN C 3 201 ? -5.653  -59.725 -36.381 1.00 93.04  ? 197 ASN C CG  1 
ATOM   4779 O OD1 . ASN C 3 201 ? -5.957  -59.651 -37.574 1.00 94.28  ? 197 ASN C OD1 1 
ATOM   4780 N ND2 . ASN C 3 201 ? -6.057  -60.719 -35.601 1.00 97.21  ? 197 ASN C ND2 1 
ATOM   4781 N N   . VAL C 3 202 ? -1.847  -57.320 -36.955 1.00 73.59  ? 198 VAL C N   1 
ATOM   4782 C CA  . VAL C 3 202 ? -1.060  -56.099 -37.079 1.00 76.04  ? 198 VAL C CA  1 
ATOM   4783 C C   . VAL C 3 202 ? -1.655  -55.255 -38.197 1.00 65.16  ? 198 VAL C C   1 
ATOM   4784 O O   . VAL C 3 202 ? -1.839  -55.743 -39.319 1.00 64.94  ? 198 VAL C O   1 
ATOM   4785 C CB  . VAL C 3 202 ? 0.423   -56.407 -37.350 1.00 67.79  ? 198 VAL C CB  1 
ATOM   4786 C CG1 . VAL C 3 202 ? 1.254   -55.141 -37.254 1.00 63.35  ? 198 VAL C CG1 1 
ATOM   4787 C CG2 . VAL C 3 202 ? 0.926   -57.460 -36.375 1.00 65.67  ? 198 VAL C CG2 1 
ATOM   4788 N N   . ASN C 3 203 ? -1.955  -53.993 -37.892 1.00 58.88  ? 199 ASN C N   1 
ATOM   4789 C CA  . ASN C 3 203 ? -2.569  -53.073 -38.844 1.00 69.48  ? 199 ASN C CA  1 
ATOM   4790 C C   . ASN C 3 203 ? -1.736  -51.800 -38.900 1.00 65.10  ? 199 ASN C C   1 
ATOM   4791 O O   . ASN C 3 203 ? -1.649  -51.067 -37.910 1.00 63.96  ? 199 ASN C O   1 
ATOM   4792 C CB  . ASN C 3 203 ? -4.014  -52.757 -38.453 1.00 64.99  ? 199 ASN C CB  1 
ATOM   4793 C CG  . ASN C 3 203 ? -4.621  -51.664 -39.309 1.00 68.47  ? 199 ASN C CG  1 
ATOM   4794 O OD1 . ASN C 3 203 ? -4.420  -51.625 -40.523 1.00 64.31  ? 199 ASN C OD1 1 
ATOM   4795 N ND2 . ASN C 3 203 ? -5.358  -50.760 -38.676 1.00 84.83  ? 199 ASN C ND2 1 
ATOM   4796 N N   . HIS C 3 204 ? -1.128  -51.541 -40.052 1.00 56.18  ? 200 HIS C N   1 
ATOM   4797 C CA  . HIS C 3 204 ? -0.395  -50.304 -40.312 1.00 56.11  ? 200 HIS C CA  1 
ATOM   4798 C C   . HIS C 3 204 ? -1.170  -49.550 -41.387 1.00 69.80  ? 200 HIS C C   1 
ATOM   4799 O O   . HIS C 3 204 ? -0.967  -49.779 -42.585 1.00 71.06  ? 200 HIS C O   1 
ATOM   4800 C CB  . HIS C 3 204 ? 1.042   -50.594 -40.745 1.00 55.14  ? 200 HIS C CB  1 
ATOM   4801 C CG  . HIS C 3 204 ? 1.832   -49.368 -41.082 1.00 52.53  ? 200 HIS C CG  1 
ATOM   4802 N ND1 . HIS C 3 204 ? 2.456   -49.190 -42.299 1.00 62.95  ? 200 HIS C ND1 1 
ATOM   4803 C CD2 . HIS C 3 204 ? 2.098   -48.255 -40.358 1.00 63.48  ? 200 HIS C CD2 1 
ATOM   4804 C CE1 . HIS C 3 204 ? 3.073   -48.022 -42.309 1.00 58.62  ? 200 HIS C CE1 1 
ATOM   4805 N NE2 . HIS C 3 204 ? 2.871   -47.435 -41.143 1.00 49.71  ? 200 HIS C NE2 1 
ATOM   4806 N N   . LYS C 3 205 ? -2.071  -48.654 -40.946 1.00 72.36  ? 201 LYS C N   1 
ATOM   4807 C CA  . LYS C 3 205 ? -2.903  -47.905 -41.889 1.00 62.91  ? 201 LYS C CA  1 
ATOM   4808 C C   . LYS C 3 205 ? -2.077  -47.147 -42.921 1.00 62.35  ? 201 LYS C C   1 
ATOM   4809 O O   . LYS C 3 205 ? -2.317  -47.357 -44.123 1.00 68.60  ? 201 LYS C O   1 
ATOM   4810 C CB  . LYS C 3 205 ? -3.863  -46.978 -41.111 1.00 59.25  ? 201 LYS C CB  1 
ATOM   4811 C CG  . LYS C 3 205 ? -4.574  -45.872 -41.913 1.00 79.49  ? 201 LYS C CG  1 
ATOM   4812 C CD  . LYS C 3 205 ? -5.314  -46.371 -43.150 1.00 90.11  ? 201 LYS C CD  1 
ATOM   4813 C CE  . LYS C 3 205 ? -6.542  -45.548 -43.568 1.00 91.34  ? 201 LYS C CE  1 
ATOM   4814 N NZ  . LYS C 3 205 ? -6.528  -45.604 -45.069 1.00 69.69  ? 201 LYS C NZ  1 
ATOM   4815 N N   . PRO C 3 206 ? -1.069  -46.334 -42.558 1.00 62.73  ? 202 PRO C N   1 
ATOM   4816 C CA  . PRO C 3 206 ? -0.393  -45.517 -43.580 1.00 61.46  ? 202 PRO C CA  1 
ATOM   4817 C C   . PRO C 3 206 ? 0.092   -46.309 -44.793 1.00 63.95  ? 202 PRO C C   1 
ATOM   4818 O O   . PRO C 3 206 ? 0.324   -45.706 -45.843 1.00 43.75  ? 202 PRO C O   1 
ATOM   4819 C CB  . PRO C 3 206 ? 0.779   -44.880 -42.809 1.00 64.56  ? 202 PRO C CB  1 
ATOM   4820 C CG  . PRO C 3 206 ? 0.313   -44.799 -41.410 1.00 63.02  ? 202 PRO C CG  1 
ATOM   4821 C CD  . PRO C 3 206 ? -0.515  -46.066 -41.214 1.00 52.75  ? 202 PRO C CD  1 
ATOM   4822 N N   . SER C 3 207 ? 0.187   -47.640 -44.699 1.00 64.99  ? 203 SER C N   1 
ATOM   4823 C CA  . SER C 3 207 ? 0.510   -48.480 -45.845 1.00 71.32  ? 203 SER C CA  1 
ATOM   4824 C C   . SER C 3 207 ? -0.568  -49.506 -46.178 1.00 66.80  ? 203 SER C C   1 
ATOM   4825 O O   . SER C 3 207 ? -0.340  -50.353 -47.050 1.00 63.92  ? 203 SER C O   1 
ATOM   4826 C CB  . SER C 3 207 ? 1.835   -49.211 -45.604 1.00 65.67  ? 203 SER C CB  1 
ATOM   4827 O OG  . SER C 3 207 ? 1.703   -50.162 -44.561 1.00 64.62  ? 203 SER C OG  1 
ATOM   4828 N N   . ASN C 3 208 ? -1.722  -49.463 -45.507 1.00 58.40  ? 204 ASN C N   1 
ATOM   4829 C CA  . ASN C 3 208 ? -2.821  -50.407 -45.703 1.00 66.86  ? 204 ASN C CA  1 
ATOM   4830 C C   . ASN C 3 208 ? -2.393  -51.856 -45.488 1.00 77.19  ? 204 ASN C C   1 
ATOM   4831 O O   . ASN C 3 208 ? -3.006  -52.775 -46.039 1.00 81.66  ? 204 ASN C O   1 
ATOM   4832 C CB  . ASN C 3 208 ? -3.459  -50.246 -47.088 1.00 80.08  ? 204 ASN C CB  1 
ATOM   4833 C CG  . ASN C 3 208 ? -4.031  -48.861 -47.304 1.00 86.54  ? 204 ASN C CG  1 
ATOM   4834 O OD1 . ASN C 3 208 ? -4.531  -48.231 -46.371 1.00 80.84  ? 204 ASN C OD1 1 
ATOM   4835 N ND2 . ASN C 3 208 ? -3.959  -48.377 -48.538 1.00 81.16  ? 204 ASN C ND2 1 
ATOM   4836 N N   . THR C 3 209 ? -1.353  -52.074 -44.688 1.00 77.34  ? 205 THR C N   1 
ATOM   4837 C CA  . THR C 3 209 ? -0.808  -53.407 -44.450 1.00 69.03  ? 205 THR C CA  1 
ATOM   4838 C C   . THR C 3 209 ? -1.523  -54.021 -43.252 1.00 66.99  ? 205 THR C C   1 
ATOM   4839 O O   . THR C 3 209 ? -1.395  -53.533 -42.125 1.00 69.10  ? 205 THR C O   1 
ATOM   4840 C CB  . THR C 3 209 ? 0.699   -53.337 -44.213 1.00 65.06  ? 205 THR C CB  1 
ATOM   4841 O OG1 . THR C 3 209 ? 1.340   -52.769 -45.363 1.00 67.73  ? 205 THR C OG1 1 
ATOM   4842 C CG2 . THR C 3 209 ? 1.264   -54.724 -43.955 1.00 54.36  ? 205 THR C CG2 1 
ATOM   4843 N N   . LYS C 3 210 ? -2.277  -55.088 -43.498 1.00 72.00  ? 206 LYS C N   1 
ATOM   4844 C CA  . LYS C 3 210 ? -2.988  -55.821 -42.453 1.00 74.33  ? 206 LYS C CA  1 
ATOM   4845 C C   . LYS C 3 210 ? -2.484  -57.260 -42.498 1.00 83.00  ? 206 LYS C C   1 
ATOM   4846 O O   . LYS C 3 210 ? -2.894  -58.042 -43.361 1.00 88.36  ? 206 LYS C O   1 
ATOM   4847 C CB  . LYS C 3 210 ? -4.499  -55.736 -42.654 1.00 73.02  ? 206 LYS C CB  1 
ATOM   4848 C CG  . LYS C 3 210 ? -5.303  -55.951 -41.384 1.00 78.97  ? 206 LYS C CG  1 
ATOM   4849 C CD  . LYS C 3 210 ? -6.788  -55.716 -41.608 1.00 85.88  ? 206 LYS C CD  1 
ATOM   4850 C CE  . LYS C 3 210 ? -7.556  -57.026 -41.613 1.00 91.86  ? 206 LYS C CE  1 
ATOM   4851 N NZ  . LYS C 3 210 ? -8.866  -56.895 -40.913 1.00 92.83  ? 206 LYS C NZ  1 
ATOM   4852 N N   . VAL C 3 211 ? -1.592  -57.605 -41.572 1.00 71.24  ? 207 VAL C N   1 
ATOM   4853 C CA  . VAL C 3 211 ? -0.894  -58.886 -41.577 1.00 68.15  ? 207 VAL C CA  1 
ATOM   4854 C C   . VAL C 3 211 ? -1.212  -59.623 -40.286 1.00 67.20  ? 207 VAL C C   1 
ATOM   4855 O O   . VAL C 3 211 ? -1.154  -59.037 -39.199 1.00 76.86  ? 207 VAL C O   1 
ATOM   4856 C CB  . VAL C 3 211 ? 0.626   -58.701 -41.738 1.00 60.07  ? 207 VAL C CB  1 
ATOM   4857 C CG1 . VAL C 3 211 ? 1.356   -60.006 -41.461 1.00 59.70  ? 207 VAL C CG1 1 
ATOM   4858 C CG2 . VAL C 3 211 ? 0.949   -58.202 -43.133 1.00 53.67  ? 207 VAL C CG2 1 
ATOM   4859 N N   . ASP C 3 212 ? -1.562  -60.901 -40.411 1.00 76.68  ? 208 ASP C N   1 
ATOM   4860 C CA  . ASP C 3 212 ? -1.800  -61.779 -39.274 1.00 88.24  ? 208 ASP C CA  1 
ATOM   4861 C C   . ASP C 3 212 ? -0.784  -62.910 -39.306 1.00 92.45  ? 208 ASP C C   1 
ATOM   4862 O O   . ASP C 3 212 ? -0.596  -63.551 -40.346 1.00 85.23  ? 208 ASP C O   1 
ATOM   4863 C CB  . ASP C 3 212 ? -3.222  -62.344 -39.298 1.00 87.43  ? 208 ASP C CB  1 
ATOM   4864 C CG  . ASP C 3 212 ? -4.271  -61.270 -39.502 1.00 93.49  ? 208 ASP C CG  1 
ATOM   4865 O OD1 . ASP C 3 212 ? -3.950  -60.079 -39.315 1.00 98.21  ? 208 ASP C OD1 1 
ATOM   4866 O OD2 . ASP C 3 212 ? -5.419  -61.615 -39.846 1.00 77.19  ? 208 ASP C OD2 1 
ATOM   4867 N N   . LYS C 3 213 ? -0.130  -63.152 -38.172 1.00 89.10  ? 209 LYS C N   1 
ATOM   4868 C CA  . LYS C 3 213 ? 0.873   -64.203 -38.058 1.00 83.01  ? 209 LYS C CA  1 
ATOM   4869 C C   . LYS C 3 213 ? 0.541   -65.098 -36.874 1.00 79.35  ? 209 LYS C C   1 
ATOM   4870 O O   . LYS C 3 213 ? 0.270   -64.604 -35.775 1.00 79.78  ? 209 LYS C O   1 
ATOM   4871 C CB  . LYS C 3 213 ? 2.281   -63.614 -37.894 1.00 84.79  ? 209 LYS C CB  1 
ATOM   4872 C CG  . LYS C 3 213 ? 3.394   -64.655 -37.889 1.00 71.99  ? 209 LYS C CG  1 
ATOM   4873 C CD  . LYS C 3 213 ? 3.413   -65.440 -39.191 1.00 79.91  ? 209 LYS C CD  1 
ATOM   4874 C CE  . LYS C 3 213 ? 3.306   -66.935 -38.939 1.00 87.45  ? 209 LYS C CE  1 
ATOM   4875 N NZ  . LYS C 3 213 ? 2.983   -67.688 -40.182 1.00 71.41  ? 209 LYS C NZ  1 
ATOM   4876 N N   . LYS C 3 214 ? 0.559   -66.407 -37.102 1.00 74.42  ? 210 LYS C N   1 
ATOM   4877 C CA  . LYS C 3 214 ? 0.420   -67.368 -36.020 1.00 76.87  ? 210 LYS C CA  1 
ATOM   4878 C C   . LYS C 3 214 ? 1.739   -67.497 -35.268 1.00 82.19  ? 210 LYS C C   1 
ATOM   4879 O O   . LYS C 3 214 ? 2.815   -67.223 -35.807 1.00 84.76  ? 210 LYS C O   1 
ATOM   4880 C CB  . LYS C 3 214 ? -0.003  -68.736 -36.559 1.00 83.48  ? 210 LYS C CB  1 
ATOM   4881 C CG  . LYS C 3 214 ? 1.152   -69.554 -37.126 1.00 84.70  ? 210 LYS C CG  1 
ATOM   4882 C CD  . LYS C 3 214 ? 0.674   -70.728 -37.968 1.00 73.33  ? 210 LYS C CD  1 
ATOM   4883 C CE  . LYS C 3 214 ? -0.014  -71.787 -37.125 1.00 72.63  ? 210 LYS C CE  1 
ATOM   4884 N NZ  . LYS C 3 214 ? -0.165  -73.064 -37.878 1.00 77.05  ? 210 LYS C NZ  1 
ATOM   4885 N N   . VAL C 3 215 ? 1.650   -67.909 -34.007 1.00 78.91  ? 211 VAL C N   1 
ATOM   4886 C CA  . VAL C 3 215 ? 2.825   -68.205 -33.197 1.00 84.21  ? 211 VAL C CA  1 
ATOM   4887 C C   . VAL C 3 215 ? 2.720   -69.653 -32.736 1.00 88.93  ? 211 VAL C C   1 
ATOM   4888 O O   . VAL C 3 215 ? 1.636   -70.118 -32.364 1.00 99.20  ? 211 VAL C O   1 
ATOM   4889 C CB  . VAL C 3 215 ? 2.974   -67.232 -32.008 1.00 91.21  ? 211 VAL C CB  1 
ATOM   4890 C CG1 . VAL C 3 215 ? 2.734   -65.795 -32.460 1.00 71.65  ? 211 VAL C CG1 1 
ATOM   4891 C CG2 . VAL C 3 215 ? 2.052   -67.597 -30.858 1.00 87.91  ? 211 VAL C CG2 1 
ATOM   4892 N N   . GLU C 3 216 ? 3.831   -70.380 -32.828 1.00 81.33  ? 212 GLU C N   1 
ATOM   4893 C CA  . GLU C 3 216 ? 3.880   -71.770 -32.402 1.00 85.85  ? 212 GLU C CA  1 
ATOM   4894 C C   . GLU C 3 216 ? 5.334   -72.143 -32.165 1.00 101.43 ? 212 GLU C C   1 
ATOM   4895 O O   . GLU C 3 216 ? 6.222   -71.607 -32.837 1.00 104.10 ? 212 GLU C O   1 
ATOM   4896 C CB  . GLU C 3 216 ? 3.244   -72.700 -33.449 1.00 88.01  ? 212 GLU C CB  1 
ATOM   4897 C CG  . GLU C 3 216 ? 3.969   -72.748 -34.785 1.00 101.08 ? 212 GLU C CG  1 
ATOM   4898 C CD  . GLU C 3 216 ? 3.383   -73.785 -35.726 1.00 120.92 ? 212 GLU C CD  1 
ATOM   4899 O OE1 . GLU C 3 216 ? 2.242   -74.233 -35.483 1.00 122.39 ? 212 GLU C OE1 1 
ATOM   4900 O OE2 . GLU C 3 216 ? 4.065   -74.157 -36.705 1.00 121.54 ? 212 GLU C OE2 1 
ATOM   4901 N N   . PRO C 3 217 ? 5.613   -73.049 -31.216 1.00 97.34  ? 213 PRO C N   1 
ATOM   4902 C CA  . PRO C 3 217 ? 6.988   -73.463 -30.913 1.00 81.95  ? 213 PRO C CA  1 
ATOM   4903 C C   . PRO C 3 217 ? 7.668   -74.169 -32.083 1.00 74.69  ? 213 PRO C C   1 
ATOM   4904 O O   . PRO C 3 217 ? 6.980   -74.802 -32.883 1.00 78.19  ? 213 PRO C O   1 
ATOM   4905 C CB  . PRO C 3 217 ? 6.813   -74.419 -29.728 1.00 74.19  ? 213 PRO C CB  1 
ATOM   4906 C CG  . PRO C 3 217 ? 5.405   -74.902 -29.834 1.00 86.84  ? 213 PRO C CG  1 
ATOM   4907 C CD  . PRO C 3 217 ? 4.630   -73.736 -30.361 1.00 85.25  ? 213 PRO C CD  1 
ATOM   4908 N N   . GLU D 4 1   ? 7.016   -13.590 -24.540 1.00 62.88  ? 1   GLU D N   1 
ATOM   4909 C CA  . GLU D 4 1   ? 6.215   -14.706 -24.051 1.00 64.70  ? 1   GLU D CA  1 
ATOM   4910 C C   . GLU D 4 1   ? 6.413   -14.914 -22.556 1.00 56.31  ? 1   GLU D C   1 
ATOM   4911 O O   . GLU D 4 1   ? 7.392   -14.444 -21.975 1.00 67.97  ? 1   GLU D O   1 
ATOM   4912 C CB  . GLU D 4 1   ? 6.567   -15.992 -24.800 1.00 66.32  ? 1   GLU D CB  1 
ATOM   4913 C CG  . GLU D 4 1   ? 6.383   -15.915 -26.305 1.00 82.26  ? 1   GLU D CG  1 
ATOM   4914 C CD  . GLU D 4 1   ? 6.714   -17.225 -26.994 1.00 102.58 ? 1   GLU D CD  1 
ATOM   4915 O OE1 . GLU D 4 1   ? 6.960   -18.224 -26.286 1.00 85.77  ? 1   GLU D OE1 1 
ATOM   4916 O OE2 . GLU D 4 1   ? 6.731   -17.254 -28.243 1.00 106.40 ? 1   GLU D OE2 1 
ATOM   4917 N N   . ILE D 4 2   ? 5.476   -15.627 -21.938 1.00 58.55  ? 2   ILE D N   1 
ATOM   4918 C CA  . ILE D 4 2   ? 5.559   -16.009 -20.534 1.00 56.89  ? 2   ILE D CA  1 
ATOM   4919 C C   . ILE D 4 2   ? 5.911   -17.487 -20.471 1.00 58.96  ? 2   ILE D C   1 
ATOM   4920 O O   . ILE D 4 2   ? 5.226   -18.322 -21.075 1.00 55.63  ? 2   ILE D O   1 
ATOM   4921 C CB  . ILE D 4 2   ? 4.245   -15.721 -19.788 1.00 50.33  ? 2   ILE D CB  1 
ATOM   4922 C CG1 . ILE D 4 2   ? 3.909   -14.231 -19.850 1.00 49.26  ? 2   ILE D CG1 1 
ATOM   4923 C CG2 . ILE D 4 2   ? 4.340   -16.185 -18.344 1.00 49.04  ? 2   ILE D CG2 1 
ATOM   4924 C CD1 . ILE D 4 2   ? 2.657   -13.855 -19.085 1.00 47.40  ? 2   ILE D CD1 1 
ATOM   4925 N N   . VAL D 4 3   ? 6.977   -17.808 -19.745 1.00 54.61  ? 3   VAL D N   1 
ATOM   4926 C CA  . VAL D 4 3   ? 7.448   -19.179 -19.595 1.00 59.22  ? 3   VAL D CA  1 
ATOM   4927 C C   . VAL D 4 3   ? 6.980   -19.704 -18.246 1.00 52.46  ? 3   VAL D C   1 
ATOM   4928 O O   . VAL D 4 3   ? 7.156   -19.041 -17.216 1.00 56.64  ? 3   VAL D O   1 
ATOM   4929 C CB  . VAL D 4 3   ? 8.980   -19.258 -19.717 1.00 52.06  ? 3   VAL D CB  1 
ATOM   4930 C CG1 . VAL D 4 3   ? 9.448   -20.701 -19.609 1.00 35.20  ? 3   VAL D CG1 1 
ATOM   4931 C CG2 . VAL D 4 3   ? 9.439   -18.635 -21.027 1.00 24.37  ? 3   VAL D CG2 1 
ATOM   4932 N N   . LEU D 4 4   ? 6.377   -20.889 -18.250 1.00 54.52  ? 4   LEU D N   1 
ATOM   4933 C CA  . LEU D 4 4   ? 5.872   -21.522 -17.039 1.00 52.03  ? 4   LEU D CA  1 
ATOM   4934 C C   . LEU D 4 4   ? 6.753   -22.713 -16.689 1.00 52.47  ? 4   LEU D C   1 
ATOM   4935 O O   . LEU D 4 4   ? 7.005   -23.575 -17.538 1.00 67.97  ? 4   LEU D O   1 
ATOM   4936 C CB  . LEU D 4 4   ? 4.420   -21.977 -17.213 1.00 64.70  ? 4   LEU D CB  1 
ATOM   4937 C CG  . LEU D 4 4   ? 3.422   -21.030 -17.886 1.00 52.48  ? 4   LEU D CG  1 
ATOM   4938 C CD1 . LEU D 4 4   ? 2.000   -21.521 -17.657 1.00 55.51  ? 4   LEU D CD1 1 
ATOM   4939 C CD2 . LEU D 4 4   ? 3.581   -19.601 -17.391 1.00 53.78  ? 4   LEU D CD2 1 
ATOM   4940 N N   . THR D 4 5   ? 7.213   -22.761 -15.442 1.00 57.24  ? 5   THR D N   1 
ATOM   4941 C CA  . THR D 4 5   ? 8.062   -23.838 -14.948 1.00 59.58  ? 5   THR D CA  1 
ATOM   4942 C C   . THR D 4 5   ? 7.297   -24.631 -13.898 1.00 64.69  ? 5   THR D C   1 
ATOM   4943 O O   . THR D 4 5   ? 6.832   -24.063 -12.903 1.00 67.94  ? 5   THR D O   1 
ATOM   4944 C CB  . THR D 4 5   ? 9.362   -23.285 -14.362 1.00 58.07  ? 5   THR D CB  1 
ATOM   4945 O OG1 . THR D 4 5   ? 10.208  -22.820 -15.422 1.00 65.10  ? 5   THR D OG1 1 
ATOM   4946 C CG2 . THR D 4 5   ? 10.091  -24.358 -13.563 1.00 63.74  ? 5   THR D CG2 1 
ATOM   4947 N N   . GLN D 4 6   ? 7.172   -25.936 -14.117 1.00 58.48  ? 6   GLN D N   1 
ATOM   4948 C CA  . GLN D 4 6   ? 6.489   -26.824 -13.189 1.00 53.11  ? 6   GLN D CA  1 
ATOM   4949 C C   . GLN D 4 6   ? 7.510   -27.573 -12.345 1.00 60.91  ? 6   GLN D C   1 
ATOM   4950 O O   . GLN D 4 6   ? 8.513   -28.073 -12.863 1.00 57.65  ? 6   GLN D O   1 
ATOM   4951 C CB  . GLN D 4 6   ? 5.598   -27.819 -13.933 1.00 58.36  ? 6   GLN D CB  1 
ATOM   4952 C CG  . GLN D 4 6   ? 4.702   -27.178 -14.975 1.00 63.64  ? 6   GLN D CG  1 
ATOM   4953 C CD  . GLN D 4 6   ? 3.480   -28.016 -15.292 1.00 57.17  ? 6   GLN D CD  1 
ATOM   4954 O OE1 . GLN D 4 6   ? 2.968   -27.987 -16.411 1.00 48.47  ? 6   GLN D OE1 1 
ATOM   4955 N NE2 . GLN D 4 6   ? 3.000   -28.762 -14.301 1.00 50.33  ? 6   GLN D NE2 1 
ATOM   4956 N N   . SER D 4 7   ? 7.252   -27.640 -11.039 1.00 73.05  ? 7   SER D N   1 
ATOM   4957 C CA  . SER D 4 7   ? 8.144   -28.309 -10.109 1.00 65.15  ? 7   SER D CA  1 
ATOM   4958 C C   . SER D 4 7   ? 7.302   -29.170 -9.175  1.00 66.95  ? 7   SER D C   1 
ATOM   4959 O O   . SER D 4 7   ? 6.278   -28.694 -8.651  1.00 76.62  ? 7   SER D O   1 
ATOM   4960 C CB  . SER D 4 7   ? 8.978   -27.307 -9.309  1.00 60.28  ? 7   SER D CB  1 
ATOM   4961 O OG  . SER D 4 7   ? 9.661   -26.414 -10.171 1.00 81.95  ? 7   SER D OG  1 
ATOM   4962 N N   . PRO D 4 8   ? 7.694   -30.426 -8.940  1.00 71.40  ? 8   PRO D N   1 
ATOM   4963 C CA  . PRO D 4 8   ? 8.868   -31.116 -9.494  1.00 76.19  ? 8   PRO D CA  1 
ATOM   4964 C C   . PRO D 4 8   ? 8.633   -31.616 -10.916 1.00 74.67  ? 8   PRO D C   1 
ATOM   4965 O O   . PRO D 4 8   ? 7.511   -31.578 -11.412 1.00 73.52  ? 8   PRO D O   1 
ATOM   4966 C CB  . PRO D 4 8   ? 9.075   -32.270 -8.507  1.00 65.44  ? 8   PRO D CB  1 
ATOM   4967 C CG  . PRO D 4 8   ? 7.685   -32.607 -8.058  1.00 58.52  ? 8   PRO D CG  1 
ATOM   4968 C CD  . PRO D 4 8   ? 6.944   -31.289 -8.009  1.00 58.60  ? 8   PRO D CD  1 
ATOM   4969 N N   . GLY D 4 9   ? 9.686   -32.069 -11.600 1.00 62.63  ? 9   GLY D N   1 
ATOM   4970 C CA  . GLY D 4 9   ? 9.504   -32.666 -12.912 1.00 44.96  ? 9   GLY D CA  1 
ATOM   4971 C C   . GLY D 4 9   ? 8.699   -33.949 -12.865 1.00 54.05  ? 9   GLY D C   1 
ATOM   4972 O O   . GLY D 4 9   ? 7.952   -34.254 -13.799 1.00 49.47  ? 9   GLY D O   1 
ATOM   4973 N N   . THR D 4 10  ? 8.845   -34.718 -11.788 1.00 62.10  ? 10  THR D N   1 
ATOM   4974 C CA  . THR D 4 10  ? 8.070   -35.932 -11.575 1.00 58.94  ? 10  THR D CA  1 
ATOM   4975 C C   . THR D 4 10  ? 8.065   -36.244 -10.085 1.00 59.01  ? 10  THR D C   1 
ATOM   4976 O O   . THR D 4 10  ? 8.875   -35.714 -9.321  1.00 62.95  ? 10  THR D O   1 
ATOM   4977 C CB  . THR D 4 10  ? 8.631   -37.115 -12.374 1.00 55.73  ? 10  THR D CB  1 
ATOM   4978 O OG1 . THR D 4 10  ? 7.980   -38.325 -11.967 1.00 61.29  ? 10  THR D OG1 1 
ATOM   4979 C CG2 . THR D 4 10  ? 10.128  -37.247 -12.152 1.00 38.13  ? 10  THR D CG2 1 
ATOM   4980 N N   . LEU D 4 11  ? 7.130   -37.100 -9.681  1.00 57.43  ? 11  LEU D N   1 
ATOM   4981 C CA  . LEU D 4 11  ? 7.072   -37.561 -8.301  1.00 67.48  ? 11  LEU D CA  1 
ATOM   4982 C C   . LEU D 4 11  ? 6.356   -38.903 -8.259  1.00 69.63  ? 11  LEU D C   1 
ATOM   4983 O O   . LEU D 4 11  ? 5.506   -39.196 -9.105  1.00 66.22  ? 11  LEU D O   1 
ATOM   4984 C CB  . LEU D 4 11  ? 6.377   -36.543 -7.383  1.00 65.65  ? 11  LEU D CB  1 
ATOM   4985 C CG  . LEU D 4 11  ? 4.966   -36.063 -7.736  1.00 77.18  ? 11  LEU D CG  1 
ATOM   4986 C CD1 . LEU D 4 11  ? 4.120   -35.884 -6.488  1.00 73.00  ? 11  LEU D CD1 1 
ATOM   4987 C CD2 . LEU D 4 11  ? 4.996   -34.763 -8.517  1.00 83.19  ? 11  LEU D CD2 1 
ATOM   4988 N N   . SER D 4 12  ? 6.718   -39.716 -7.265  1.00 58.26  ? 12  SER D N   1 
ATOM   4989 C CA  . SER D 4 12  ? 6.175   -41.059 -7.082  1.00 74.18  ? 12  SER D CA  1 
ATOM   4990 C C   . SER D 4 12  ? 5.522   -41.135 -5.707  1.00 80.24  ? 12  SER D C   1 
ATOM   4991 O O   . SER D 4 12  ? 6.210   -41.067 -4.682  1.00 93.65  ? 12  SER D O   1 
ATOM   4992 C CB  . SER D 4 12  ? 7.264   -42.120 -7.227  1.00 77.93  ? 12  SER D CB  1 
ATOM   4993 O OG  . SER D 4 12  ? 6.715   -43.419 -7.084  1.00 75.26  ? 12  SER D OG  1 
ATOM   4994 N N   . LEU D 4 13  ? 4.199   -41.259 -5.684  1.00 63.68  ? 13  LEU D N   1 
ATOM   4995 C CA  . LEU D 4 13  ? 3.436   -41.302 -4.446  1.00 73.70  ? 13  LEU D CA  1 
ATOM   4996 C C   . LEU D 4 13  ? 2.656   -42.609 -4.364  1.00 67.77  ? 13  LEU D C   1 
ATOM   4997 O O   . LEU D 4 13  ? 2.590   -43.388 -5.319  1.00 65.48  ? 13  LEU D O   1 
ATOM   4998 C CB  . LEU D 4 13  ? 2.488   -40.097 -4.338  1.00 89.69  ? 13  LEU D CB  1 
ATOM   4999 C CG  . LEU D 4 13  ? 3.008   -38.783 -3.734  1.00 87.13  ? 13  LEU D CG  1 
ATOM   5000 C CD1 . LEU D 4 13  ? 2.941   -38.818 -2.228  1.00 86.39  ? 13  LEU D CD1 1 
ATOM   5001 C CD2 . LEU D 4 13  ? 4.426   -38.474 -4.159  1.00 69.02  ? 13  LEU D CD2 1 
ATOM   5002 N N   . SER D 4 14  ? 2.064   -42.846 -3.195  1.00 64.03  ? 14  SER D N   1 
ATOM   5003 C CA  . SER D 4 14  ? 1.303   -44.055 -2.931  1.00 73.68  ? 14  SER D CA  1 
ATOM   5004 C C   . SER D 4 14  ? -0.187  -43.740 -2.833  1.00 79.39  ? 14  SER D C   1 
ATOM   5005 O O   . SER D 4 14  ? -0.566  -42.606 -2.522  1.00 82.56  ? 14  SER D O   1 
ATOM   5006 C CB  . SER D 4 14  ? 1.768   -44.722 -1.631  1.00 83.43  ? 14  SER D CB  1 
ATOM   5007 O OG  . SER D 4 14  ? 3.148   -45.036 -1.688  1.00 73.41  ? 14  SER D OG  1 
ATOM   5008 N N   . PRO D 4 15  ? -1.056  -44.712 -3.114  1.00 74.05  ? 15  PRO D N   1 
ATOM   5009 C CA  . PRO D 4 15  ? -2.499  -44.468 -2.979  1.00 85.94  ? 15  PRO D CA  1 
ATOM   5010 C C   . PRO D 4 15  ? -2.867  -44.075 -1.554  1.00 85.40  ? 15  PRO D C   1 
ATOM   5011 O O   . PRO D 4 15  ? -2.426  -44.696 -0.584  1.00 82.34  ? 15  PRO D O   1 
ATOM   5012 C CB  . PRO D 4 15  ? -3.123  -45.811 -3.377  1.00 73.88  ? 15  PRO D CB  1 
ATOM   5013 C CG  . PRO D 4 15  ? -2.099  -46.456 -4.251  1.00 71.56  ? 15  PRO D CG  1 
ATOM   5014 C CD  . PRO D 4 15  ? -0.771  -46.037 -3.692  1.00 56.27  ? 15  PRO D CD  1 
ATOM   5015 N N   . GLY D 4 16  ? -3.688  -43.031 -1.436  1.00 83.11  ? 16  GLY D N   1 
ATOM   5016 C CA  . GLY D 4 16  ? -4.148  -42.532 -0.160  1.00 73.23  ? 16  GLY D CA  1 
ATOM   5017 C C   . GLY D 4 16  ? -3.356  -41.364 0.396   1.00 82.16  ? 16  GLY D C   1 
ATOM   5018 O O   . GLY D 4 16  ? -3.835  -40.694 1.317   1.00 93.02  ? 16  GLY D O   1 
ATOM   5019 N N   . GLU D 4 17  ? -2.162  -41.104 -0.135  1.00 60.67  ? 17  GLU D N   1 
ATOM   5020 C CA  . GLU D 4 17  ? -1.331  -39.989 0.309   1.00 67.56  ? 17  GLU D CA  1 
ATOM   5021 C C   . GLU D 4 17  ? -1.790  -38.688 -0.341  1.00 75.13  ? 17  GLU D C   1 
ATOM   5022 O O   . GLU D 4 17  ? -2.924  -38.599 -0.824  1.00 82.70  ? 17  GLU D O   1 
ATOM   5023 C CB  . GLU D 4 17  ? 0.146   -40.271 0.014   1.00 79.58  ? 17  GLU D CB  1 
ATOM   5024 C CG  . GLU D 4 17  ? 0.745   -41.344 0.928   1.00 94.08  ? 17  GLU D CG  1 
ATOM   5025 C CD  . GLU D 4 17  ? 2.257   -41.443 0.847   1.00 93.09  ? 17  GLU D CD  1 
ATOM   5026 O OE1 . GLU D 4 17  ? 2.889   -40.548 0.249   1.00 81.25  ? 17  GLU D OE1 1 
ATOM   5027 O OE2 . GLU D 4 17  ? 2.809   -42.424 1.394   1.00 100.72 ? 17  GLU D OE2 1 
ATOM   5028 N N   . ARG D 4 18  ? -0.952  -37.654 -0.294  1.00 78.07  ? 18  ARG D N   1 
ATOM   5029 C CA  . ARG D 4 18  ? -1.253  -36.369 -0.912  1.00 74.29  ? 18  ARG D CA  1 
ATOM   5030 C C   . ARG D 4 18  ? -0.081  -35.910 -1.767  1.00 71.20  ? 18  ARG D C   1 
ATOM   5031 O O   . ARG D 4 18  ? 1.076   -35.981 -1.342  1.00 85.00  ? 18  ARG D O   1 
ATOM   5032 C CB  . ARG D 4 18  ? -1.568  -35.308 0.146   1.00 76.57  ? 18  ARG D CB  1 
ATOM   5033 C CG  . ARG D 4 18  ? -1.763  -33.910 -0.412  1.00 79.78  ? 18  ARG D CG  1 
ATOM   5034 C CD  . ARG D 4 18  ? -2.009  -32.911 0.699   1.00 77.76  ? 18  ARG D CD  1 
ATOM   5035 N NE  . ARG D 4 18  ? -3.204  -33.242 1.464   1.00 86.60  ? 18  ARG D NE  1 
ATOM   5036 C CZ  . ARG D 4 18  ? -3.643  -32.543 2.501   1.00 92.99  ? 18  ARG D CZ  1 
ATOM   5037 N NH1 . ARG D 4 18  ? -3.002  -31.468 2.929   1.00 104.47 ? 18  ARG D NH1 1 
ATOM   5038 N NH2 . ARG D 4 18  ? -4.752  -32.932 3.123   1.00 82.13  ? 18  ARG D NH2 1 
ATOM   5039 N N   . ALA D 4 19  ? -0.390  -35.425 -2.967  1.00 65.34  ? 19  ALA D N   1 
ATOM   5040 C CA  . ALA D 4 19  ? 0.605   -34.939 -3.912  1.00 71.00  ? 19  ALA D CA  1 
ATOM   5041 C C   . ALA D 4 19  ? 0.442   -33.438 -4.112  1.00 58.71  ? 19  ALA D C   1 
ATOM   5042 O O   . ALA D 4 19  ? -0.681  -32.936 -4.219  1.00 70.76  ? 19  ALA D O   1 
ATOM   5043 C CB  . ALA D 4 19  ? 0.484   -35.661 -5.256  1.00 74.82  ? 19  ALA D CB  1 
ATOM   5044 N N   . THR D 4 20  ? 1.567   -32.728 -4.163  1.00 49.82  ? 20  THR D N   1 
ATOM   5045 C CA  . THR D 4 20  ? 1.589   -31.270 -4.277  1.00 66.13  ? 20  THR D CA  1 
ATOM   5046 C C   . THR D 4 20  ? 2.415   -30.875 -5.499  1.00 65.16  ? 20  THR D C   1 
ATOM   5047 O O   . THR D 4 20  ? 3.649   -30.919 -5.469  1.00 64.19  ? 20  THR D O   1 
ATOM   5048 C CB  . THR D 4 20  ? 2.142   -30.633 -3.004  1.00 82.79  ? 20  THR D CB  1 
ATOM   5049 O OG1 . THR D 4 20  ? 2.634   -29.319 -3.301  1.00 54.43  ? 20  THR D OG1 1 
ATOM   5050 C CG2 . THR D 4 20  ? 3.263   -31.483 -2.415  1.00 89.02  ? 20  THR D CG2 1 
ATOM   5051 N N   . LEU D 4 21  ? 1.730   -30.483 -6.567  1.00 55.69  ? 21  LEU D N   1 
ATOM   5052 C CA  . LEU D 4 21  ? 2.367   -30.018 -7.788  1.00 44.00  ? 21  LEU D CA  1 
ATOM   5053 C C   . LEU D 4 21  ? 2.376   -28.494 -7.811  1.00 49.63  ? 21  LEU D C   1 
ATOM   5054 O O   . LEU D 4 21  ? 1.463   -27.845 -7.295  1.00 59.54  ? 21  LEU D O   1 
ATOM   5055 C CB  . LEU D 4 21  ? 1.650   -30.560 -9.029  1.00 51.27  ? 21  LEU D CB  1 
ATOM   5056 C CG  . LEU D 4 21  ? 1.616   -32.073 -9.274  1.00 63.98  ? 21  LEU D CG  1 
ATOM   5057 C CD1 . LEU D 4 21  ? 0.550   -32.769 -8.439  1.00 61.98  ? 21  LEU D CD1 1 
ATOM   5058 C CD2 . LEU D 4 21  ? 1.381   -32.341 -10.740 1.00 64.19  ? 21  LEU D CD2 1 
ATOM   5059 N N   . SER D 4 22  ? 3.422   -27.926 -8.409  1.00 47.97  ? 22  SER D N   1 
ATOM   5060 C CA  . SER D 4 22  ? 3.625   -26.485 -8.407  1.00 55.47  ? 22  SER D CA  1 
ATOM   5061 C C   . SER D 4 22  ? 3.880   -25.977 -9.821  1.00 65.87  ? 22  SER D C   1 
ATOM   5062 O O   . SER D 4 22  ? 4.446   -26.679 -10.662 1.00 69.39  ? 22  SER D O   1 
ATOM   5063 C CB  . SER D 4 22  ? 4.795   -26.091 -7.494  1.00 56.78  ? 22  SER D CB  1 
ATOM   5064 O OG  . SER D 4 22  ? 4.647   -26.663 -6.204  1.00 83.36  ? 22  SER D OG  1 
ATOM   5065 N N   . CYS D 4 23  ? 3.449   -24.740 -10.068 1.00 66.76  ? 23  CYS D N   1 
ATOM   5066 C CA  . CYS D 4 23  ? 3.660   -24.048 -11.333 1.00 67.39  ? 23  CYS D CA  1 
ATOM   5067 C C   . CYS D 4 23  ? 4.150   -22.642 -11.023 1.00 63.96  ? 23  CYS D C   1 
ATOM   5068 O O   . CYS D 4 23  ? 3.543   -21.938 -10.209 1.00 71.90  ? 23  CYS D O   1 
ATOM   5069 C CB  . CYS D 4 23  ? 2.366   -24.002 -12.158 1.00 68.07  ? 23  CYS D CB  1 
ATOM   5070 S SG  . CYS D 4 23  ? 2.466   -23.296 -13.830 1.00 84.90  ? 23  CYS D SG  1 
ATOM   5071 N N   . ARG D 4 24  ? 5.249   -22.240 -11.657 1.00 58.05  ? 24  ARG D N   1 
ATOM   5072 C CA  . ARG D 4 24  ? 5.871   -20.947 -11.411 1.00 52.45  ? 24  ARG D CA  1 
ATOM   5073 C C   . ARG D 4 24  ? 6.031   -20.209 -12.732 1.00 52.55  ? 24  ARG D C   1 
ATOM   5074 O O   . ARG D 4 24  ? 6.435   -20.802 -13.737 1.00 70.61  ? 24  ARG D O   1 
ATOM   5075 C CB  . ARG D 4 24  ? 7.230   -21.117 -10.716 1.00 70.76  ? 24  ARG D CB  1 
ATOM   5076 C CG  . ARG D 4 24  ? 7.167   -21.987 -9.461  1.00 67.73  ? 24  ARG D CG  1 
ATOM   5077 C CD  . ARG D 4 24  ? 8.504   -22.050 -8.738  1.00 75.37  ? 24  ARG D CD  1 
ATOM   5078 N NE  . ARG D 4 24  ? 9.238   -23.279 -9.019  1.00 93.99  ? 24  ARG D NE  1 
ATOM   5079 C CZ  . ARG D 4 24  ? 10.423  -23.574 -8.501  1.00 95.83  ? 24  ARG D CZ  1 
ATOM   5080 N NH1 . ARG D 4 24  ? 11.039  -22.749 -7.670  1.00 88.73  ? 24  ARG D NH1 1 
ATOM   5081 N NH2 . ARG D 4 24  ? 11.006  -24.725 -8.825  1.00 89.09  ? 24  ARG D NH2 1 
ATOM   5082 N N   . ALA D 4 25  ? 5.719   -18.916 -12.728 1.00 51.29  ? 25  ALA D N   1 
ATOM   5083 C CA  . ALA D 4 25  ? 5.614   -18.132 -13.949 1.00 66.58  ? 25  ALA D CA  1 
ATOM   5084 C C   . ALA D 4 25  ? 6.707   -17.072 -14.022 1.00 61.22  ? 25  ALA D C   1 
ATOM   5085 O O   . ALA D 4 25  ? 7.255   -16.634 -13.008 1.00 60.56  ? 25  ALA D O   1 
ATOM   5086 C CB  . ALA D 4 25  ? 4.238   -17.465 -14.050 1.00 61.59  ? 25  ALA D CB  1 
ATOM   5087 N N   . SER D 4 26  ? 7.019   -16.664 -15.257 1.00 57.09  ? 26  SER D N   1 
ATOM   5088 C CA  . SER D 4 26  ? 8.019   -15.622 -15.466 1.00 51.17  ? 26  SER D CA  1 
ATOM   5089 C C   . SER D 4 26  ? 7.479   -14.243 -15.109 1.00 65.79  ? 26  SER D C   1 
ATOM   5090 O O   . SER D 4 26  ? 8.256   -13.346 -14.762 1.00 63.83  ? 26  SER D O   1 
ATOM   5091 C CB  . SER D 4 26  ? 8.504   -15.639 -16.916 1.00 47.60  ? 26  SER D CB  1 
ATOM   5092 O OG  . SER D 4 26  ? 7.478   -15.228 -17.803 1.00 47.42  ? 26  SER D OG  1 
ATOM   5093 N N   . GLN D 4 27  ? 6.164   -14.050 -15.205 1.00 72.24  ? 27  GLN D N   1 
ATOM   5094 C CA  . GLN D 4 27  ? 5.519   -12.794 -14.852 1.00 55.17  ? 27  GLN D CA  1 
ATOM   5095 C C   . GLN D 4 27  ? 4.249   -13.110 -14.071 1.00 76.67  ? 27  GLN D C   1 
ATOM   5096 O O   . GLN D 4 27  ? 3.942   -14.273 -13.793 1.00 84.81  ? 27  GLN D O   1 
ATOM   5097 C CB  . GLN D 4 27  ? 5.214   -11.956 -16.101 1.00 42.53  ? 27  GLN D CB  1 
ATOM   5098 C CG  . GLN D 4 27  ? 6.433   -11.629 -16.951 1.00 52.58  ? 27  GLN D CG  1 
ATOM   5099 C CD  . GLN D 4 27  ? 6.061   -11.085 -18.316 1.00 62.89  ? 27  GLN D CD  1 
ATOM   5100 O OE1 . GLN D 4 27  ? 4.986   -10.515 -18.497 1.00 69.99  ? 27  GLN D OE1 1 
ATOM   5101 N NE2 . GLN D 4 27  ? 6.949   -11.266 -19.287 1.00 71.81  ? 27  GLN D NE2 1 
ATOM   5102 N N   . SER D 4 28  ? 3.507   -12.067 -13.712 1.00 72.42  ? 28  SER D N   1 
ATOM   5103 C CA  . SER D 4 28  ? 2.253   -12.250 -12.995 1.00 71.02  ? 28  SER D CA  1 
ATOM   5104 C C   . SER D 4 28  ? 1.127   -12.566 -13.971 1.00 76.39  ? 28  SER D C   1 
ATOM   5105 O O   . SER D 4 28  ? 1.055   -11.999 -15.065 1.00 68.73  ? 28  SER D O   1 
ATOM   5106 C CB  . SER D 4 28  ? 1.907   -11.000 -12.187 1.00 66.60  ? 28  SER D CB  1 
ATOM   5107 O OG  . SER D 4 28  ? 1.529   -9.931  -13.037 1.00 80.83  ? 28  SER D OG  1 
ATOM   5108 N N   . VAL D 4 29  ? 0.248   -13.482 -13.571 1.00 81.70  ? 29  VAL D N   1 
ATOM   5109 C CA  . VAL D 4 29  ? -0.914  -13.842 -14.376 1.00 71.53  ? 29  VAL D CA  1 
ATOM   5110 C C   . VAL D 4 29  ? -2.232  -13.610 -13.653 1.00 67.97  ? 29  VAL D C   1 
ATOM   5111 O O   . VAL D 4 29  ? -3.291  -13.704 -14.293 1.00 77.04  ? 29  VAL D O   1 
ATOM   5112 C CB  . VAL D 4 29  ? -0.831  -15.303 -14.868 1.00 72.56  ? 29  VAL D CB  1 
ATOM   5113 C CG1 . VAL D 4 29  ? 0.218   -15.433 -15.960 1.00 64.41  ? 29  VAL D CG1 1 
ATOM   5114 C CG2 . VAL D 4 29  ? -0.506  -16.226 -13.714 1.00 51.30  ? 29  VAL D CG2 1 
ATOM   5115 N N   . SER D 4 30  ? -2.209  -13.316 -12.351 1.00 54.05  ? 30  SER D N   1 
ATOM   5116 C CA  . SER D 4 30  ? -3.398  -12.928 -11.589 1.00 59.55  ? 30  SER D CA  1 
ATOM   5117 C C   . SER D 4 30  ? -4.476  -14.014 -11.638 1.00 67.66  ? 30  SER D C   1 
ATOM   5118 O O   . SER D 4 30  ? -5.610  -13.786 -12.063 1.00 73.88  ? 30  SER D O   1 
ATOM   5119 C CB  . SER D 4 30  ? -3.944  -11.585 -12.085 1.00 56.74  ? 30  SER D CB  1 
ATOM   5120 O OG  . SER D 4 30  ? -2.923  -10.604 -12.116 1.00 77.87  ? 30  SER D OG  1 
ATOM   5121 N N   . SER D 4 31  ? -4.092  -15.211 -11.195 1.00 65.45  ? 31  SER D N   1 
ATOM   5122 C CA  . SER D 4 31  ? -4.961  -16.381 -11.084 1.00 83.42  ? 31  SER D CA  1 
ATOM   5123 C C   . SER D 4 31  ? -5.523  -16.841 -12.425 1.00 64.31  ? 31  SER D C   1 
ATOM   5124 O O   . SER D 4 31  ? -6.424  -17.688 -12.453 1.00 56.91  ? 31  SER D O   1 
ATOM   5125 C CB  . SER D 4 31  ? -6.115  -16.139 -10.102 1.00 78.78  ? 31  SER D CB  1 
ATOM   5126 O OG  . SER D 4 31  ? -7.056  -15.224 -10.636 1.00 83.51  ? 31  SER D OG  1 
ATOM   5127 N N   . TYR D 4 32  ? -5.017  -16.311 -13.540 1.00 44.07  ? 32  TYR D N   1 
ATOM   5128 C CA  . TYR D 4 32  ? -5.457  -16.739 -14.867 1.00 51.23  ? 32  TYR D CA  1 
ATOM   5129 C C   . TYR D 4 32  ? -4.674  -17.982 -15.301 1.00 58.98  ? 32  TYR D C   1 
ATOM   5130 O O   . TYR D 4 32  ? -3.942  -17.989 -16.290 1.00 49.90  ? 32  TYR D O   1 
ATOM   5131 C CB  . TYR D 4 32  ? -5.301  -15.606 -15.875 1.00 52.91  ? 32  TYR D CB  1 
ATOM   5132 C CG  . TYR D 4 32  ? -6.126  -14.370 -15.579 1.00 65.48  ? 32  TYR D CG  1 
ATOM   5133 C CD1 . TYR D 4 32  ? -7.224  -14.424 -14.729 1.00 73.48  ? 32  TYR D CD1 1 
ATOM   5134 C CD2 . TYR D 4 32  ? -5.807  -13.148 -16.158 1.00 59.06  ? 32  TYR D CD2 1 
ATOM   5135 C CE1 . TYR D 4 32  ? -7.976  -13.294 -14.460 1.00 64.03  ? 32  TYR D CE1 1 
ATOM   5136 C CE2 . TYR D 4 32  ? -6.553  -12.014 -15.896 1.00 62.32  ? 32  TYR D CE2 1 
ATOM   5137 C CZ  . TYR D 4 32  ? -7.636  -12.093 -15.047 1.00 69.19  ? 32  TYR D CZ  1 
ATOM   5138 O OH  . TYR D 4 32  ? -8.383  -10.968 -14.783 1.00 68.68  ? 32  TYR D OH  1 
ATOM   5139 N N   . LEU D 4 33  ? -4.846  -19.052 -14.526 1.00 45.68  ? 33  LEU D N   1 
ATOM   5140 C CA  . LEU D 4 33  ? -4.137  -20.303 -14.749 1.00 42.19  ? 33  LEU D CA  1 
ATOM   5141 C C   . LEU D 4 33  ? -5.117  -21.467 -14.705 1.00 47.80  ? 33  LEU D C   1 
ATOM   5142 O O   . LEU D 4 33  ? -6.099  -21.447 -13.957 1.00 48.90  ? 33  LEU D O   1 
ATOM   5143 C CB  . LEU D 4 33  ? -3.035  -20.518 -13.703 1.00 47.90  ? 33  LEU D CB  1 
ATOM   5144 C CG  . LEU D 4 33  ? -2.047  -21.646 -14.007 1.00 49.96  ? 33  LEU D CG  1 
ATOM   5145 C CD1 . LEU D 4 33  ? -0.920  -21.142 -14.897 1.00 44.50  ? 33  LEU D CD1 1 
ATOM   5146 C CD2 . LEU D 4 33  ? -1.503  -22.264 -12.730 1.00 49.38  ? 33  LEU D CD2 1 
ATOM   5147 N N   . ALA D 4 34  ? -4.833  -22.488 -15.510 1.00 45.90  ? 34  ALA D N   1 
ATOM   5148 C CA  . ALA D 4 34  ? -5.644  -23.693 -15.574 1.00 51.00  ? 34  ALA D CA  1 
ATOM   5149 C C   . ALA D 4 34  ? -4.743  -24.916 -15.476 1.00 51.38  ? 34  ALA D C   1 
ATOM   5150 O O   . ALA D 4 34  ? -3.538  -24.848 -15.736 1.00 39.00  ? 34  ALA D O   1 
ATOM   5151 C CB  . ALA D 4 34  ? -6.472  -23.749 -16.865 1.00 46.16  ? 34  ALA D CB  1 
ATOM   5152 N N   . TRP D 4 35  ? -5.341  -26.043 -15.092 1.00 35.72  ? 35  TRP D N   1 
ATOM   5153 C CA  . TRP D 4 35  ? -4.619  -27.297 -14.937 1.00 35.02  ? 35  TRP D CA  1 
ATOM   5154 C C   . TRP D 4 35  ? -5.325  -28.401 -15.708 1.00 47.27  ? 35  TRP D C   1 
ATOM   5155 O O   . TRP D 4 35  ? -6.556  -28.428 -15.785 1.00 63.06  ? 35  TRP D O   1 
ATOM   5156 C CB  . TRP D 4 35  ? -4.495  -27.687 -13.464 1.00 50.80  ? 35  TRP D CB  1 
ATOM   5157 C CG  . TRP D 4 35  ? -3.539  -26.829 -12.703 1.00 52.20  ? 35  TRP D CG  1 
ATOM   5158 C CD1 . TRP D 4 35  ? -3.814  -25.650 -12.076 1.00 46.86  ? 35  TRP D CD1 1 
ATOM   5159 C CD2 . TRP D 4 35  ? -2.147  -27.082 -12.487 1.00 63.19  ? 35  TRP D CD2 1 
ATOM   5160 N NE1 . TRP D 4 35  ? -2.682  -25.154 -11.480 1.00 44.63  ? 35  TRP D NE1 1 
ATOM   5161 C CE2 . TRP D 4 35  ? -1.644  -26.015 -11.718 1.00 69.05  ? 35  TRP D CE2 1 
ATOM   5162 C CE3 . TRP D 4 35  ? -1.278  -28.108 -12.869 1.00 60.89  ? 35  TRP D CE3 1 
ATOM   5163 C CZ2 . TRP D 4 35  ? -0.311  -25.946 -11.323 1.00 67.55  ? 35  TRP D CZ2 1 
ATOM   5164 C CZ3 . TRP D 4 35  ? 0.045   -28.037 -12.476 1.00 59.01  ? 35  TRP D CZ3 1 
ATOM   5165 C CH2 . TRP D 4 35  ? 0.516   -26.963 -11.712 1.00 57.43  ? 35  TRP D CH2 1 
ATOM   5166 N N   . TYR D 4 36  ? -4.536  -29.318 -16.268 1.00 48.02  ? 36  TYR D N   1 
ATOM   5167 C CA  . TYR D 4 36  ? -5.046  -30.389 -17.110 1.00 42.52  ? 36  TYR D CA  1 
ATOM   5168 C C   . TYR D 4 36  ? -4.419  -31.714 -16.697 1.00 38.28  ? 36  TYR D C   1 
ATOM   5169 O O   . TYR D 4 36  ? -3.334  -31.757 -16.113 1.00 45.49  ? 36  TYR D O   1 
ATOM   5170 C CB  . TYR D 4 36  ? -4.759  -30.117 -18.596 1.00 40.90  ? 36  TYR D CB  1 
ATOM   5171 C CG  . TYR D 4 36  ? -5.308  -28.801 -19.099 1.00 38.73  ? 36  TYR D CG  1 
ATOM   5172 C CD1 . TYR D 4 36  ? -4.572  -27.629 -18.981 1.00 37.11  ? 36  TYR D CD1 1 
ATOM   5173 C CD2 . TYR D 4 36  ? -6.560  -28.732 -19.693 1.00 33.34  ? 36  TYR D CD2 1 
ATOM   5174 C CE1 . TYR D 4 36  ? -5.070  -26.425 -19.439 1.00 45.97  ? 36  TYR D CE1 1 
ATOM   5175 C CE2 . TYR D 4 36  ? -7.065  -27.534 -20.155 1.00 40.00  ? 36  TYR D CE2 1 
ATOM   5176 C CZ  . TYR D 4 36  ? -6.318  -26.383 -20.025 1.00 45.45  ? 36  TYR D CZ  1 
ATOM   5177 O OH  . TYR D 4 36  ? -6.820  -25.186 -20.484 1.00 49.11  ? 36  TYR D OH  1 
ATOM   5178 N N   . GLN D 4 37  ? -5.122  -32.802 -17.006 1.00 51.08  ? 37  GLN D N   1 
ATOM   5179 C CA  . GLN D 4 37  ? -4.639  -34.154 -16.754 1.00 37.75  ? 37  GLN D CA  1 
ATOM   5180 C C   . GLN D 4 37  ? -4.671  -34.940 -18.054 1.00 42.63  ? 37  GLN D C   1 
ATOM   5181 O O   . GLN D 4 37  ? -5.713  -35.006 -18.715 1.00 48.44  ? 37  GLN D O   1 
ATOM   5182 C CB  . GLN D 4 37  ? -5.487  -34.864 -15.694 1.00 33.32  ? 37  GLN D CB  1 
ATOM   5183 C CG  . GLN D 4 37  ? -5.122  -36.326 -15.489 1.00 50.44  ? 37  GLN D CG  1 
ATOM   5184 C CD  . GLN D 4 37  ? -6.213  -37.107 -14.779 1.00 54.53  ? 37  GLN D CD  1 
ATOM   5185 O OE1 . GLN D 4 37  ? -7.372  -36.694 -14.755 1.00 55.62  ? 37  GLN D OE1 1 
ATOM   5186 N NE2 . GLN D 4 37  ? -5.846  -38.243 -14.197 1.00 58.84  ? 37  GLN D NE2 1 
ATOM   5187 N N   . GLN D 4 38  ? -3.541  -35.542 -18.417 1.00 54.47  ? 38  GLN D N   1 
ATOM   5188 C CA  . GLN D 4 38  ? -3.422  -36.304 -19.658 1.00 45.61  ? 38  GLN D CA  1 
ATOM   5189 C C   . GLN D 4 38  ? -2.941  -37.713 -19.329 1.00 38.90  ? 38  GLN D C   1 
ATOM   5190 O O   . GLN D 4 38  ? -1.741  -37.943 -19.148 1.00 58.95  ? 38  GLN D O   1 
ATOM   5191 C CB  . GLN D 4 38  ? -2.478  -35.615 -20.641 1.00 37.47  ? 38  GLN D CB  1 
ATOM   5192 C CG  . GLN D 4 38  ? -2.381  -36.321 -21.987 1.00 41.93  ? 38  GLN D CG  1 
ATOM   5193 C CD  . GLN D 4 38  ? -1.457  -35.614 -22.962 1.00 49.33  ? 38  GLN D CD  1 
ATOM   5194 O OE1 . GLN D 4 38  ? -1.484  -35.882 -24.164 1.00 47.08  ? 38  GLN D OE1 1 
ATOM   5195 N NE2 . GLN D 4 38  ? -0.632  -34.710 -22.448 1.00 42.62  ? 38  GLN D NE2 1 
ATOM   5196 N N   . LYS D 4 39  ? -3.878  -38.652 -19.249 1.00 36.78  ? 39  LYS D N   1 
ATOM   5197 C CA  . LYS D 4 39  ? -3.515  -40.054 -19.153 1.00 48.80  ? 39  LYS D CA  1 
ATOM   5198 C C   . LYS D 4 39  ? -2.914  -40.523 -20.478 1.00 56.25  ? 39  LYS D C   1 
ATOM   5199 O O   . LYS D 4 39  ? -3.242  -39.985 -21.539 1.00 57.63  ? 39  LYS D O   1 
ATOM   5200 C CB  . LYS D 4 39  ? -4.737  -40.895 -18.799 1.00 44.97  ? 39  LYS D CB  1 
ATOM   5201 C CG  . LYS D 4 39  ? -5.205  -40.728 -17.365 1.00 40.70  ? 39  LYS D CG  1 
ATOM   5202 C CD  . LYS D 4 39  ? -6.713  -40.861 -17.281 1.00 58.95  ? 39  LYS D CD  1 
ATOM   5203 C CE  . LYS D 4 39  ? -7.163  -41.267 -15.893 1.00 62.28  ? 39  LYS D CE  1 
ATOM   5204 N NZ  . LYS D 4 39  ? -8.523  -41.869 -15.946 1.00 66.43  ? 39  LYS D NZ  1 
ATOM   5205 N N   . PRO D 4 40  ? -2.021  -41.514 -20.442 1.00 59.33  ? 40  PRO D N   1 
ATOM   5206 C CA  . PRO D 4 40  ? -1.368  -41.956 -21.681 1.00 66.27  ? 40  PRO D CA  1 
ATOM   5207 C C   . PRO D 4 40  ? -2.377  -42.463 -22.701 1.00 59.53  ? 40  PRO D C   1 
ATOM   5208 O O   . PRO D 4 40  ? -3.361  -43.124 -22.359 1.00 47.33  ? 40  PRO D O   1 
ATOM   5209 C CB  . PRO D 4 40  ? -0.429  -43.073 -21.209 1.00 62.49  ? 40  PRO D CB  1 
ATOM   5210 C CG  . PRO D 4 40  ? -0.997  -43.523 -19.901 1.00 57.51  ? 40  PRO D CG  1 
ATOM   5211 C CD  . PRO D 4 40  ? -1.572  -42.292 -19.276 1.00 57.97  ? 40  PRO D CD  1 
ATOM   5212 N N   . GLY D 4 41  ? -2.123  -42.137 -23.968 1.00 56.75  ? 41  GLY D N   1 
ATOM   5213 C CA  . GLY D 4 41  ? -3.003  -42.540 -25.047 1.00 58.17  ? 41  GLY D CA  1 
ATOM   5214 C C   . GLY D 4 41  ? -4.306  -41.783 -25.131 1.00 63.53  ? 41  GLY D C   1 
ATOM   5215 O O   . GLY D 4 41  ? -5.199  -42.199 -25.877 1.00 67.63  ? 41  GLY D O   1 
ATOM   5216 N N   . GLN D 4 42  ? -4.449  -40.683 -24.395 1.00 64.48  ? 42  GLN D N   1 
ATOM   5217 C CA  . GLN D 4 42  ? -5.701  -39.944 -24.350 1.00 54.79  ? 42  GLN D CA  1 
ATOM   5218 C C   . GLN D 4 42  ? -5.417  -38.450 -24.314 1.00 53.47  ? 42  GLN D C   1 
ATOM   5219 O O   . GLN D 4 42  ? -4.301  -38.010 -24.029 1.00 47.90  ? 42  GLN D O   1 
ATOM   5220 C CB  . GLN D 4 42  ? -6.553  -40.363 -23.144 1.00 50.81  ? 42  GLN D CB  1 
ATOM   5221 C CG  . GLN D 4 42  ? -7.299  -41.671 -23.364 1.00 60.96  ? 42  GLN D CG  1 
ATOM   5222 C CD  . GLN D 4 42  ? -7.604  -42.403 -22.074 1.00 73.36  ? 42  GLN D CD  1 
ATOM   5223 O OE1 . GLN D 4 42  ? -7.370  -41.887 -20.981 1.00 61.01  ? 42  GLN D OE1 1 
ATOM   5224 N NE2 . GLN D 4 42  ? -8.125  -43.620 -22.196 1.00 79.26  ? 42  GLN D NE2 1 
ATOM   5225 N N   . ALA D 4 43  ? -6.454  -37.677 -24.621 1.00 48.02  ? 43  ALA D N   1 
ATOM   5226 C CA  . ALA D 4 43  ? -6.374  -36.229 -24.685 1.00 47.24  ? 43  ALA D CA  1 
ATOM   5227 C C   . ALA D 4 43  ? -6.301  -35.621 -23.288 1.00 47.30  ? 43  ALA D C   1 
ATOM   5228 O O   . ALA D 4 43  ? -6.705  -36.246 -22.305 1.00 44.71  ? 43  ALA D O   1 
ATOM   5229 C CB  . ALA D 4 43  ? -7.586  -35.678 -25.424 1.00 49.71  ? 43  ALA D CB  1 
ATOM   5230 N N   . PRO D 4 44  ? -5.777  -34.399 -23.173 1.00 38.35  ? 44  PRO D N   1 
ATOM   5231 C CA  . PRO D 4 44  ? -5.814  -33.706 -21.881 1.00 34.70  ? 44  PRO D CA  1 
ATOM   5232 C C   . PRO D 4 44  ? -7.244  -33.489 -21.408 1.00 38.54  ? 44  PRO D C   1 
ATOM   5233 O O   . PRO D 4 44  ? -8.153  -33.238 -22.202 1.00 39.66  ? 44  PRO D O   1 
ATOM   5234 C CB  . PRO D 4 44  ? -5.108  -32.376 -22.170 1.00 39.73  ? 44  PRO D CB  1 
ATOM   5235 C CG  . PRO D 4 44  ? -4.241  -32.658 -23.351 1.00 41.90  ? 44  PRO D CG  1 
ATOM   5236 C CD  . PRO D 4 44  ? -4.999  -33.654 -24.179 1.00 36.81  ? 44  PRO D CD  1 
ATOM   5237 N N   . ARG D 4 45  ? -7.435  -33.594 -20.094 1.00 46.93  ? 45  ARG D N   1 
ATOM   5238 C CA  . ARG D 4 45  ? -8.736  -33.443 -19.454 1.00 36.78  ? 45  ARG D CA  1 
ATOM   5239 C C   . ARG D 4 45  ? -8.659  -32.278 -18.479 1.00 45.57  ? 45  ARG D C   1 
ATOM   5240 O O   . ARG D 4 45  ? -7.812  -32.276 -17.579 1.00 54.04  ? 45  ARG D O   1 
ATOM   5241 C CB  . ARG D 4 45  ? -9.133  -34.740 -18.743 1.00 33.85  ? 45  ARG D CB  1 
ATOM   5242 C CG  . ARG D 4 45  ? -10.103 -34.599 -17.582 1.00 50.95  ? 45  ARG D CG  1 
ATOM   5243 C CD  . ARG D 4 45  ? -10.259 -35.948 -16.889 1.00 70.61  ? 45  ARG D CD  1 
ATOM   5244 N NE  . ARG D 4 45  ? -11.031 -35.879 -15.655 1.00 95.32  ? 45  ARG D NE  1 
ATOM   5245 C CZ  . ARG D 4 45  ? -11.052 -36.837 -14.737 1.00 82.99  ? 45  ARG D CZ  1 
ATOM   5246 N NH1 . ARG D 4 45  ? -10.348 -37.949 -14.882 1.00 79.22  ? 45  ARG D NH1 1 
ATOM   5247 N NH2 . ARG D 4 45  ? -11.793 -36.674 -13.644 1.00 68.65  ? 45  ARG D NH2 1 
ATOM   5248 N N   . LEU D 4 46  ? -9.529  -31.285 -18.666 1.00 51.70  ? 46  LEU D N   1 
ATOM   5249 C CA  . LEU D 4 46  ? -9.510  -30.104 -17.812 1.00 47.95  ? 46  LEU D CA  1 
ATOM   5250 C C   . LEU D 4 46  ? -9.826  -30.486 -16.372 1.00 54.51  ? 46  LEU D C   1 
ATOM   5251 O O   . LEU D 4 46  ? -10.775 -31.229 -16.107 1.00 42.86  ? 46  LEU D O   1 
ATOM   5252 C CB  . LEU D 4 46  ? -10.514 -29.066 -18.315 1.00 42.38  ? 46  LEU D CB  1 
ATOM   5253 C CG  . LEU D 4 46  ? -10.630 -27.786 -17.480 1.00 44.81  ? 46  LEU D CG  1 
ATOM   5254 C CD1 . LEU D 4 46  ? -9.389  -26.920 -17.629 1.00 45.27  ? 46  LEU D CD1 1 
ATOM   5255 C CD2 . LEU D 4 46  ? -11.882 -27.003 -17.842 1.00 41.79  ? 46  LEU D CD2 1 
ATOM   5256 N N   . LEU D 4 47  ? -9.024  -29.973 -15.438 1.00 54.67  ? 47  LEU D N   1 
ATOM   5257 C CA  . LEU D 4 47  ? -9.198  -30.258 -14.020 1.00 60.95  ? 47  LEU D CA  1 
ATOM   5258 C C   . LEU D 4 47  ? -9.680  -29.038 -13.247 1.00 54.19  ? 47  LEU D C   1 
ATOM   5259 O O   . LEU D 4 47  ? -10.721 -29.097 -12.585 1.00 52.89  ? 47  LEU D O   1 
ATOM   5260 C CB  . LEU D 4 47  ? -7.887  -30.781 -13.418 1.00 46.95  ? 47  LEU D CB  1 
ATOM   5261 C CG  . LEU D 4 47  ? -7.572  -32.257 -13.651 1.00 45.84  ? 47  LEU D CG  1 
ATOM   5262 C CD1 . LEU D 4 47  ? -6.280  -32.629 -12.953 1.00 63.84  ? 47  LEU D CD1 1 
ATOM   5263 C CD2 . LEU D 4 47  ? -8.719  -33.127 -13.162 1.00 49.71  ? 47  LEU D CD2 1 
ATOM   5264 N N   . ILE D 4 48  ? -8.943  -27.928 -13.298 1.00 41.85  ? 48  ILE D N   1 
ATOM   5265 C CA  . ILE D 4 48  ? -9.356  -26.699 -12.636 1.00 52.30  ? 48  ILE D CA  1 
ATOM   5266 C C   . ILE D 4 48  ? -9.148  -25.526 -13.583 1.00 49.42  ? 48  ILE D C   1 
ATOM   5267 O O   . ILE D 4 48  ? -8.309  -25.569 -14.487 1.00 52.25  ? 48  ILE D O   1 
ATOM   5268 C CB  . ILE D 4 48  ? -8.608  -26.447 -11.302 1.00 60.59  ? 48  ILE D CB  1 
ATOM   5269 C CG1 . ILE D 4 48  ? -7.250  -25.792 -11.548 1.00 48.39  ? 48  ILE D CG1 1 
ATOM   5270 C CG2 . ILE D 4 48  ? -8.434  -27.736 -10.510 1.00 44.78  ? 48  ILE D CG2 1 
ATOM   5271 C CD1 . ILE D 4 48  ? -6.620  -25.244 -10.290 1.00 55.24  ? 48  ILE D CD1 1 
ATOM   5272 N N   . TYR D 4 49  ? -9.929  -24.470 -13.365 1.00 54.62  ? 49  TYR D N   1 
ATOM   5273 C CA  . TYR D 4 49  ? -9.808  -23.222 -14.102 1.00 52.59  ? 49  TYR D CA  1 
ATOM   5274 C C   . TYR D 4 49  ? -9.841  -22.065 -13.116 1.00 50.19  ? 49  TYR D C   1 
ATOM   5275 O O   . TYR D 4 49  ? -10.399 -22.178 -12.021 1.00 53.51  ? 49  TYR D O   1 
ATOM   5276 C CB  . TYR D 4 49  ? -10.925 -23.063 -15.150 1.00 50.92  ? 49  TYR D CB  1 
ATOM   5277 C CG  . TYR D 4 49  ? -12.328 -23.198 -14.597 1.00 56.53  ? 49  TYR D CG  1 
ATOM   5278 C CD1 . TYR D 4 49  ? -13.023 -22.089 -14.129 1.00 41.96  ? 49  TYR D CD1 1 
ATOM   5279 C CD2 . TYR D 4 49  ? -12.959 -24.434 -14.551 1.00 58.26  ? 49  TYR D CD2 1 
ATOM   5280 C CE1 . TYR D 4 49  ? -14.305 -22.210 -13.625 1.00 45.91  ? 49  TYR D CE1 1 
ATOM   5281 C CE2 . TYR D 4 49  ? -14.241 -24.564 -14.051 1.00 59.13  ? 49  TYR D CE2 1 
ATOM   5282 C CZ  . TYR D 4 49  ? -14.909 -23.449 -13.589 1.00 60.58  ? 49  TYR D CZ  1 
ATOM   5283 O OH  . TYR D 4 49  ? -16.186 -23.573 -13.090 1.00 52.31  ? 49  TYR D OH  1 
ATOM   5284 N N   . GLY D 4 50  ? -9.227  -20.951 -13.511 1.00 38.11  ? 50  GLY D N   1 
ATOM   5285 C CA  . GLY D 4 50  ? -9.129  -19.811 -12.622 1.00 44.67  ? 50  GLY D CA  1 
ATOM   5286 C C   . GLY D 4 50  ? -8.282  -20.042 -11.395 1.00 48.46  ? 50  GLY D C   1 
ATOM   5287 O O   . GLY D 4 50  ? -8.357  -19.249 -10.451 1.00 41.64  ? 50  GLY D O   1 
ATOM   5288 N N   . ALA D 4 51  ? -7.485  -21.111 -11.384 1.00 60.94  ? 51  ALA D N   1 
ATOM   5289 C CA  . ALA D 4 51  ? -6.582  -21.532 -10.317 1.00 47.15  ? 51  ALA D CA  1 
ATOM   5290 C C   . ALA D 4 51  ? -7.303  -22.069 -9.086  1.00 41.85  ? 51  ALA D C   1 
ATOM   5291 O O   . ALA D 4 51  ? -6.633  -22.526 -8.152  1.00 54.24  ? 51  ALA D O   1 
ATOM   5292 C CB  . ALA D 4 51  ? -5.629  -20.410 -9.880  1.00 39.43  ? 51  ALA D CB  1 
ATOM   5293 N N   . SER D 4 52  ? -8.631  -22.037 -9.043  1.00 44.32  ? 52  SER D N   1 
ATOM   5294 C CA  . SER D 4 52  ? -9.318  -22.546 -7.858  1.00 43.87  ? 52  SER D CA  1 
ATOM   5295 C C   . SER D 4 52  ? -10.459 -23.506 -8.164  1.00 51.73  ? 52  SER D C   1 
ATOM   5296 O O   . SER D 4 52  ? -10.654 -24.471 -7.421  1.00 45.49  ? 52  SER D O   1 
ATOM   5297 C CB  . SER D 4 52  ? -9.849  -21.370 -7.021  1.00 45.73  ? 52  SER D CB  1 
ATOM   5298 O OG  . SER D 4 52  ? -8.791  -20.542 -6.574  1.00 56.85  ? 52  SER D OG  1 
ATOM   5299 N N   . SER D 4 53  ? -11.210 -23.273 -9.239  1.00 49.82  ? 53  SER D N   1 
ATOM   5300 C CA  . SER D 4 53  ? -12.507 -23.913 -9.433  1.00 53.92  ? 53  SER D CA  1 
ATOM   5301 C C   . SER D 4 53  ? -12.372 -25.218 -10.207 1.00 55.87  ? 53  SER D C   1 
ATOM   5302 O O   . SER D 4 53  ? -11.695 -25.267 -11.237 1.00 58.15  ? 53  SER D O   1 
ATOM   5303 C CB  . SER D 4 53  ? -13.456 -22.970 -10.174 1.00 56.84  ? 53  SER D CB  1 
ATOM   5304 O OG  . SER D 4 53  ? -13.466 -21.684 -9.581  1.00 60.52  ? 53  SER D OG  1 
ATOM   5305 N N   . ARG D 4 54  ? -13.030 -26.266 -9.714  1.00 46.00  ? 54  ARG D N   1 
ATOM   5306 C CA  . ARG D 4 54  ? -13.117 -27.517 -10.454 1.00 50.12  ? 54  ARG D CA  1 
ATOM   5307 C C   . ARG D 4 54  ? -14.014 -27.353 -11.675 1.00 62.12  ? 54  ARG D C   1 
ATOM   5308 O O   . ARG D 4 54  ? -14.938 -26.536 -11.691 1.00 63.23  ? 54  ARG D O   1 
ATOM   5309 C CB  . ARG D 4 54  ? -13.674 -28.638 -9.575  1.00 52.81  ? 54  ARG D CB  1 
ATOM   5310 C CG  . ARG D 4 54  ? -12.918 -28.888 -8.292  1.00 48.95  ? 54  ARG D CG  1 
ATOM   5311 C CD  . ARG D 4 54  ? -13.827 -28.690 -7.091  1.00 63.33  ? 54  ARG D CD  1 
ATOM   5312 N NE  . ARG D 4 54  ? -13.124 -28.893 -5.831  1.00 73.30  ? 54  ARG D NE  1 
ATOM   5313 C CZ  . ARG D 4 54  ? -12.258 -28.034 -5.312  1.00 74.59  ? 54  ARG D CZ  1 
ATOM   5314 N NH1 . ARG D 4 54  ? -11.939 -26.911 -5.935  1.00 63.80  ? 54  ARG D NH1 1 
ATOM   5315 N NH2 . ARG D 4 54  ? -11.695 -28.310 -4.139  1.00 71.83  ? 54  ARG D NH2 1 
ATOM   5316 N N   . ALA D 4 55  ? -13.735 -28.147 -12.704 1.00 63.68  ? 55  ALA D N   1 
ATOM   5317 C CA  . ALA D 4 55  ? -14.612 -28.215 -13.860 1.00 64.17  ? 55  ALA D CA  1 
ATOM   5318 C C   . ALA D 4 55  ? -15.756 -29.190 -13.584 1.00 60.82  ? 55  ALA D C   1 
ATOM   5319 O O   . ALA D 4 55  ? -15.862 -29.778 -12.504 1.00 63.92  ? 55  ALA D O   1 
ATOM   5320 C CB  . ALA D 4 55  ? -13.824 -28.615 -15.104 1.00 77.27  ? 55  ALA D CB  1 
ATOM   5321 N N   . THR D 4 56  ? -16.629 -29.364 -14.571 1.00 63.47  ? 56  THR D N   1 
ATOM   5322 C CA  . THR D 4 56  ? -17.760 -30.268 -14.412 1.00 82.33  ? 56  THR D CA  1 
ATOM   5323 C C   . THR D 4 56  ? -17.274 -31.712 -14.347 1.00 80.10  ? 56  THR D C   1 
ATOM   5324 O O   . THR D 4 56  ? -16.480 -32.151 -15.185 1.00 85.40  ? 56  THR D O   1 
ATOM   5325 C CB  . THR D 4 56  ? -18.749 -30.091 -15.564 1.00 77.61  ? 56  THR D CB  1 
ATOM   5326 O OG1 . THR D 4 56  ? -19.305 -28.770 -15.519 1.00 83.89  ? 56  THR D OG1 1 
ATOM   5327 C CG2 . THR D 4 56  ? -19.875 -31.112 -15.467 1.00 71.63  ? 56  THR D CG2 1 
ATOM   5328 N N   . GLY D 4 57  ? -17.752 -32.449 -13.345 1.00 66.35  ? 57  GLY D N   1 
ATOM   5329 C CA  . GLY D 4 57  ? -17.389 -33.839 -13.171 1.00 58.30  ? 57  GLY D CA  1 
ATOM   5330 C C   . GLY D 4 57  ? -16.095 -34.087 -12.428 1.00 68.49  ? 57  GLY D C   1 
ATOM   5331 O O   . GLY D 4 57  ? -15.724 -35.253 -12.241 1.00 65.24  ? 57  GLY D O   1 
ATOM   5332 N N   . ILE D 4 58  ? -15.397 -33.043 -12.005 1.00 77.16  ? 58  ILE D N   1 
ATOM   5333 C CA  . ILE D 4 58  ? -14.126 -33.213 -11.297 1.00 73.80  ? 58  ILE D CA  1 
ATOM   5334 C C   . ILE D 4 58  ? -14.415 -33.619 -9.854  1.00 76.09  ? 58  ILE D C   1 
ATOM   5335 O O   . ILE D 4 58  ? -15.220 -32.954 -9.182  1.00 76.46  ? 58  ILE D O   1 
ATOM   5336 C CB  . ILE D 4 58  ? -13.303 -31.931 -11.353 1.00 63.73  ? 58  ILE D CB  1 
ATOM   5337 C CG1 . ILE D 4 58  ? -13.171 -31.449 -12.798 1.00 62.48  ? 58  ILE D CG1 1 
ATOM   5338 C CG2 . ILE D 4 58  ? -11.925 -32.159 -10.751 1.00 62.78  ? 58  ILE D CG2 1 
ATOM   5339 C CD1 . ILE D 4 58  ? -12.521 -32.454 -13.720 1.00 65.37  ? 58  ILE D CD1 1 
ATOM   5340 N N   . PRO D 4 59  ? -13.799 -34.687 -9.352  1.00 85.77  ? 59  PRO D N   1 
ATOM   5341 C CA  . PRO D 4 59  ? -14.037 -35.096 -7.964  1.00 94.09  ? 59  PRO D CA  1 
ATOM   5342 C C   . PRO D 4 59  ? -13.527 -34.060 -6.973  1.00 87.30  ? 59  PRO D C   1 
ATOM   5343 O O   . PRO D 4 59  ? -12.694 -33.206 -7.286  1.00 69.04  ? 59  PRO D O   1 
ATOM   5344 C CB  . PRO D 4 59  ? -13.258 -36.411 -7.839  1.00 82.73  ? 59  PRO D CB  1 
ATOM   5345 C CG  . PRO D 4 59  ? -13.104 -36.899 -9.244  1.00 79.49  ? 59  PRO D CG  1 
ATOM   5346 C CD  . PRO D 4 59  ? -12.973 -35.663 -10.081 1.00 83.75  ? 59  PRO D CD  1 
ATOM   5347 N N   . ASP D 4 60  ? -14.057 -34.149 -5.751  1.00 93.48  ? 60  ASP D N   1 
ATOM   5348 C CA  . ASP D 4 60  ? -13.699 -33.205 -4.698  1.00 88.84  ? 60  ASP D CA  1 
ATOM   5349 C C   . ASP D 4 60  ? -12.239 -33.316 -4.279  1.00 84.93  ? 60  ASP D C   1 
ATOM   5350 O O   . ASP D 4 60  ? -11.703 -32.365 -3.701  1.00 71.94  ? 60  ASP D O   1 
ATOM   5351 C CB  . ASP D 4 60  ? -14.598 -33.418 -3.480  1.00 88.78  ? 60  ASP D CB  1 
ATOM   5352 C CG  . ASP D 4 60  ? -16.058 -33.572 -3.853  1.00 103.21 ? 60  ASP D CG  1 
ATOM   5353 O OD1 . ASP D 4 60  ? -16.416 -34.620 -4.432  1.00 94.00  ? 60  ASP D OD1 1 
ATOM   5354 O OD2 . ASP D 4 60  ? -16.847 -32.648 -3.568  1.00 117.21 ? 60  ASP D OD2 1 
ATOM   5355 N N   . ARG D 4 61  ? -11.589 -34.451 -4.553  1.00 86.44  ? 61  ARG D N   1 
ATOM   5356 C CA  . ARG D 4 61  ? -10.217 -34.651 -4.097  1.00 59.68  ? 61  ARG D CA  1 
ATOM   5357 C C   . ARG D 4 61  ? -9.260  -33.643 -4.720  1.00 65.45  ? 61  ARG D C   1 
ATOM   5358 O O   . ARG D 4 61  ? -8.252  -33.279 -4.102  1.00 64.25  ? 61  ARG D O   1 
ATOM   5359 C CB  . ARG D 4 61  ? -9.762  -36.075 -4.415  1.00 68.08  ? 61  ARG D CB  1 
ATOM   5360 C CG  . ARG D 4 61  ? -10.895 -37.062 -4.641  1.00 78.05  ? 61  ARG D CG  1 
ATOM   5361 C CD  . ARG D 4 61  ? -10.361 -38.472 -4.843  1.00 82.88  ? 61  ARG D CD  1 
ATOM   5362 N NE  . ARG D 4 61  ? -11.328 -39.333 -5.514  1.00 96.42  ? 61  ARG D NE  1 
ATOM   5363 C CZ  . ARG D 4 61  ? -11.317 -39.598 -6.813  1.00 94.59  ? 61  ARG D CZ  1 
ATOM   5364 N NH1 . ARG D 4 61  ? -10.390 -39.096 -7.613  1.00 77.13  ? 61  ARG D NH1 1 
ATOM   5365 N NH2 . ARG D 4 61  ? -12.258 -40.389 -7.323  1.00 78.43  ? 61  ARG D NH2 1 
ATOM   5366 N N   . PHE D 4 62  ? -9.551  -33.187 -5.935  1.00 81.34  ? 62  PHE D N   1 
ATOM   5367 C CA  . PHE D 4 62  ? -8.684  -32.241 -6.621  1.00 80.53  ? 62  PHE D CA  1 
ATOM   5368 C C   . PHE D 4 62  ? -8.936  -30.828 -6.113  1.00 68.49  ? 62  PHE D C   1 
ATOM   5369 O O   . PHE D 4 62  ? -10.083 -30.423 -5.900  1.00 67.71  ? 62  PHE D O   1 
ATOM   5370 C CB  . PHE D 4 62  ? -8.913  -32.310 -8.132  1.00 70.06  ? 62  PHE D CB  1 
ATOM   5371 C CG  . PHE D 4 62  ? -8.631  -33.662 -8.727  1.00 71.33  ? 62  PHE D CG  1 
ATOM   5372 C CD1 . PHE D 4 62  ? -9.570  -34.680 -8.651  1.00 67.93  ? 62  PHE D CD1 1 
ATOM   5373 C CD2 . PHE D 4 62  ? -7.429  -33.914 -9.367  1.00 66.49  ? 62  PHE D CD2 1 
ATOM   5374 C CE1 . PHE D 4 62  ? -9.313  -35.924 -9.195  1.00 73.47  ? 62  PHE D CE1 1 
ATOM   5375 C CE2 . PHE D 4 62  ? -7.167  -35.156 -9.916  1.00 69.14  ? 62  PHE D CE2 1 
ATOM   5376 C CZ  . PHE D 4 62  ? -8.112  -36.161 -9.830  1.00 76.73  ? 62  PHE D CZ  1 
ATOM   5377 N N   . SER D 4 63  ? -7.854  -30.078 -5.916  1.00 53.37  ? 63  SER D N   1 
ATOM   5378 C CA  . SER D 4 63  ? -7.954  -28.722 -5.400  1.00 61.74  ? 63  SER D CA  1 
ATOM   5379 C C   . SER D 4 63  ? -6.879  -27.855 -6.037  1.00 64.01  ? 63  SER D C   1 
ATOM   5380 O O   . SER D 4 63  ? -5.777  -28.323 -6.338  1.00 70.32  ? 63  SER D O   1 
ATOM   5381 C CB  . SER D 4 63  ? -7.820  -28.690 -3.873  1.00 71.31  ? 63  SER D CB  1 
ATOM   5382 O OG  . SER D 4 63  ? -7.479  -27.391 -3.419  1.00 74.54  ? 63  SER D OG  1 
ATOM   5383 N N   . GLY D 4 64  ? -7.214  -26.582 -6.234  1.00 52.28  ? 64  GLY D N   1 
ATOM   5384 C CA  . GLY D 4 64  ? -6.262  -25.611 -6.731  1.00 55.65  ? 64  GLY D CA  1 
ATOM   5385 C C   . GLY D 4 64  ? -6.066  -24.465 -5.760  1.00 75.01  ? 64  GLY D C   1 
ATOM   5386 O O   . GLY D 4 64  ? -6.944  -24.187 -4.938  1.00 83.41  ? 64  GLY D O   1 
ATOM   5387 N N   . SER D 4 65  ? -4.921  -23.793 -5.842  1.00 61.54  ? 65  SER D N   1 
ATOM   5388 C CA  . SER D 4 65  ? -4.603  -22.705 -4.926  1.00 40.42  ? 65  SER D CA  1 
ATOM   5389 C C   . SER D 4 65  ? -3.528  -21.834 -5.562  1.00 44.97  ? 65  SER D C   1 
ATOM   5390 O O   . SER D 4 65  ? -3.106  -22.062 -6.699  1.00 52.52  ? 65  SER D O   1 
ATOM   5391 C CB  . SER D 4 65  ? -4.162  -23.246 -3.562  1.00 59.14  ? 65  SER D CB  1 
ATOM   5392 O OG  . SER D 4 65  ? -3.226  -24.300 -3.710  1.00 70.61  ? 65  SER D OG  1 
ATOM   5393 N N   . GLY D 4 66  ? -3.093  -20.825 -4.818  1.00 52.93  ? 66  GLY D N   1 
ATOM   5394 C CA  . GLY D 4 66  ? -2.072  -19.913 -5.284  1.00 57.58  ? 66  GLY D CA  1 
ATOM   5395 C C   . GLY D 4 66  ? -2.628  -18.832 -6.195  1.00 57.01  ? 66  GLY D C   1 
ATOM   5396 O O   . GLY D 4 66  ? -3.744  -18.913 -6.707  1.00 61.08  ? 66  GLY D O   1 
ATOM   5397 N N   . SER D 4 67  ? -1.819  -17.793 -6.392  1.00 42.45  ? 67  SER D N   1 
ATOM   5398 C CA  . SER D 4 67  ? -2.197  -16.688 -7.261  1.00 55.57  ? 67  SER D CA  1 
ATOM   5399 C C   . SER D 4 67  ? -0.953  -15.889 -7.617  1.00 62.38  ? 67  SER D C   1 
ATOM   5400 O O   . SER D 4 67  ? 0.079   -15.977 -6.946  1.00 67.95  ? 67  SER D O   1 
ATOM   5401 C CB  . SER D 4 67  ? -3.245  -15.783 -6.602  1.00 76.20  ? 67  SER D CB  1 
ATOM   5402 O OG  . SER D 4 67  ? -2.742  -15.202 -5.412  1.00 81.01  ? 67  SER D OG  1 
ATOM   5403 N N   . GLY D 4 68  ? -1.069  -15.107 -8.687  1.00 60.02  ? 68  GLY D N   1 
ATOM   5404 C CA  . GLY D 4 68  ? -0.014  -14.198 -9.089  1.00 57.28  ? 68  GLY D CA  1 
ATOM   5405 C C   . GLY D 4 68  ? 1.095   -14.836 -9.899  1.00 71.87  ? 68  GLY D C   1 
ATOM   5406 O O   . GLY D 4 68  ? 1.152   -14.665 -11.120 1.00 55.76  ? 68  GLY D O   1 
ATOM   5407 N N   . THR D 4 69  ? 1.993   -15.561 -9.233  1.00 83.93  ? 69  THR D N   1 
ATOM   5408 C CA  . THR D 4 69  ? 3.116   -16.181 -9.926  1.00 77.72  ? 69  THR D CA  1 
ATOM   5409 C C   . THR D 4 69  ? 3.284   -17.648 -9.542  1.00 69.44  ? 69  THR D C   1 
ATOM   5410 O O   . THR D 4 69  ? 3.695   -18.469 -10.368 1.00 68.52  ? 69  THR D O   1 
ATOM   5411 C CB  . THR D 4 69  ? 4.402   -15.400 -9.634  1.00 74.67  ? 69  THR D CB  1 
ATOM   5412 O OG1 . THR D 4 69  ? 4.229   -14.034 -10.031 1.00 72.25  ? 69  THR D OG1 1 
ATOM   5413 C CG2 . THR D 4 69  ? 5.579   -15.990 -10.392 1.00 71.12  ? 69  THR D CG2 1 
ATOM   5414 N N   . ASP D 4 70  ? 2.953   -17.992 -8.300  1.00 57.30  ? 70  ASP D N   1 
ATOM   5415 C CA  . ASP D 4 70  ? 3.176   -19.329 -7.765  1.00 54.89  ? 70  ASP D CA  1 
ATOM   5416 C C   . ASP D 4 70  ? 1.838   -20.012 -7.515  1.00 59.68  ? 70  ASP D C   1 
ATOM   5417 O O   . ASP D 4 70  ? 0.934   -19.417 -6.919  1.00 70.18  ? 70  ASP D O   1 
ATOM   5418 C CB  . ASP D 4 70  ? 3.993   -19.271 -6.471  1.00 68.35  ? 70  ASP D CB  1 
ATOM   5419 C CG  . ASP D 4 70  ? 5.338   -18.588 -6.656  1.00 75.23  ? 70  ASP D CG  1 
ATOM   5420 O OD1 . ASP D 4 70  ? 5.606   -18.068 -7.760  1.00 46.93  ? 70  ASP D OD1 1 
ATOM   5421 O OD2 . ASP D 4 70  ? 6.133   -18.571 -5.692  1.00 84.07  ? 70  ASP D OD2 1 
ATOM   5422 N N   . PHE D 4 71  ? 1.721   -21.262 -7.962  1.00 55.80  ? 71  PHE D N   1 
ATOM   5423 C CA  . PHE D 4 71  ? 0.472   -22.004 -7.873  1.00 53.22  ? 71  PHE D CA  1 
ATOM   5424 C C   . PHE D 4 71  ? 0.751   -23.417 -7.386  1.00 50.58  ? 71  PHE D C   1 
ATOM   5425 O O   . PHE D 4 71  ? 1.866   -23.931 -7.508  1.00 53.42  ? 71  PHE D O   1 
ATOM   5426 C CB  . PHE D 4 71  ? -0.254  -22.044 -9.222  1.00 50.83  ? 71  PHE D CB  1 
ATOM   5427 C CG  . PHE D 4 71  ? -0.458  -20.692 -9.833  1.00 55.51  ? 71  PHE D CG  1 
ATOM   5428 C CD1 . PHE D 4 71  ? 0.503   -20.143 -10.666 1.00 52.67  ? 71  PHE D CD1 1 
ATOM   5429 C CD2 . PHE D 4 71  ? -1.606  -19.965 -9.570  1.00 61.48  ? 71  PHE D CD2 1 
ATOM   5430 C CE1 . PHE D 4 71  ? 0.320   -18.896 -11.227 1.00 53.12  ? 71  PHE D CE1 1 
ATOM   5431 C CE2 . PHE D 4 71  ? -1.794  -18.718 -10.130 1.00 60.52  ? 71  PHE D CE2 1 
ATOM   5432 C CZ  . PHE D 4 71  ? -0.830  -18.183 -10.957 1.00 46.44  ? 71  PHE D CZ  1 
ATOM   5433 N N   . THR D 4 72  ? -0.284  -24.045 -6.830  1.00 43.95  ? 72  THR D N   1 
ATOM   5434 C CA  . THR D 4 72  ? -0.167  -25.386 -6.277  1.00 54.57  ? 72  THR D CA  1 
ATOM   5435 C C   . THR D 4 72  ? -1.395  -26.204 -6.642  1.00 70.16  ? 72  THR D C   1 
ATOM   5436 O O   . THR D 4 72  ? -2.526  -25.775 -6.396  1.00 84.48  ? 72  THR D O   1 
ATOM   5437 C CB  . THR D 4 72  ? 0.002   -25.344 -4.754  1.00 72.45  ? 72  THR D CB  1 
ATOM   5438 O OG1 . THR D 4 72  ? 1.201   -24.633 -4.425  1.00 69.28  ? 72  THR D OG1 1 
ATOM   5439 C CG2 . THR D 4 72  ? 0.083   -26.755 -4.186  1.00 67.59  ? 72  THR D CG2 1 
ATOM   5440 N N   . LEU D 4 73  ? -1.167  -27.379 -7.227  1.00 66.27  ? 73  LEU D N   1 
ATOM   5441 C CA  . LEU D 4 73  ? -2.222  -28.344 -7.509  1.00 67.67  ? 73  LEU D CA  1 
ATOM   5442 C C   . LEU D 4 73  ? -2.135  -29.453 -6.467  1.00 58.24  ? 73  LEU D C   1 
ATOM   5443 O O   . LEU D 4 73  ? -1.143  -30.187 -6.416  1.00 68.25  ? 73  LEU D O   1 
ATOM   5444 C CB  . LEU D 4 73  ? -2.088  -28.909 -8.922  1.00 64.89  ? 73  LEU D CB  1 
ATOM   5445 C CG  . LEU D 4 73  ? -3.322  -29.610 -9.495  1.00 62.73  ? 73  LEU D CG  1 
ATOM   5446 C CD1 . LEU D 4 73  ? -4.418  -28.596 -9.792  1.00 55.59  ? 73  LEU D CD1 1 
ATOM   5447 C CD2 . LEU D 4 73  ? -2.971  -30.408 -10.741 1.00 47.14  ? 73  LEU D CD2 1 
ATOM   5448 N N   . THR D 4 74  ? -3.167  -29.569 -5.638  1.00 47.38  ? 74  THR D N   1 
ATOM   5449 C CA  . THR D 4 74  ? -3.154  -30.462 -4.483  1.00 65.37  ? 74  THR D CA  1 
ATOM   5450 C C   . THR D 4 74  ? -4.212  -31.540 -4.674  1.00 73.00  ? 74  THR D C   1 
ATOM   5451 O O   . THR D 4 74  ? -5.385  -31.340 -4.347  1.00 75.11  ? 74  THR D O   1 
ATOM   5452 C CB  . THR D 4 74  ? -3.390  -29.682 -3.193  1.00 64.15  ? 74  THR D CB  1 
ATOM   5453 O OG1 . THR D 4 74  ? -2.445  -28.607 -3.105  1.00 57.49  ? 74  THR D OG1 1 
ATOM   5454 C CG2 . THR D 4 74  ? -3.232  -30.596 -1.986  1.00 62.54  ? 74  THR D CG2 1 
ATOM   5455 N N   . ILE D 4 75  ? -3.799  -32.687 -5.200  1.00 67.29  ? 75  ILE D N   1 
ATOM   5456 C CA  . ILE D 4 75  ? -4.670  -33.851 -5.289  1.00 72.30  ? 75  ILE D CA  1 
ATOM   5457 C C   . ILE D 4 75  ? -4.489  -34.683 -4.030  1.00 64.49  ? 75  ILE D C   1 
ATOM   5458 O O   . ILE D 4 75  ? -3.360  -35.014 -3.648  1.00 68.96  ? 75  ILE D O   1 
ATOM   5459 C CB  . ILE D 4 75  ? -4.359  -34.679 -6.542  1.00 65.00  ? 75  ILE D CB  1 
ATOM   5460 C CG1 . ILE D 4 75  ? -4.224  -33.766 -7.759  1.00 65.21  ? 75  ILE D CG1 1 
ATOM   5461 C CG2 . ILE D 4 75  ? -5.438  -35.718 -6.768  1.00 68.53  ? 75  ILE D CG2 1 
ATOM   5462 C CD1 . ILE D 4 75  ? -2.832  -33.840 -8.421  1.00 65.42  ? 75  ILE D CD1 1 
ATOM   5463 N N   . SER D 4 76  ? -5.597  -35.024 -3.385  1.00 66.81  ? 76  SER D N   1 
ATOM   5464 C CA  . SER D 4 76  ? -5.591  -35.847 -2.188  1.00 77.03  ? 76  SER D CA  1 
ATOM   5465 C C   . SER D 4 76  ? -6.357  -37.136 -2.458  1.00 79.44  ? 76  SER D C   1 
ATOM   5466 O O   . SER D 4 76  ? -7.029  -37.279 -3.483  1.00 90.03  ? 76  SER D O   1 
ATOM   5467 C CB  . SER D 4 76  ? -6.204  -35.090 -1.004  1.00 74.54  ? 76  SER D CB  1 
ATOM   5468 O OG  . SER D 4 76  ? -5.666  -33.781 -0.900  1.00 54.07  ? 76  SER D OG  1 
ATOM   5469 N N   . ARG D 4 77  ? -6.253  -38.080 -1.521  1.00 70.25  ? 77  ARG D N   1 
ATOM   5470 C CA  . ARG D 4 77  ? -6.951  -39.365 -1.613  1.00 80.89  ? 77  ARG D CA  1 
ATOM   5471 C C   . ARG D 4 77  ? -6.654  -40.042 -2.949  1.00 88.39  ? 77  ARG D C   1 
ATOM   5472 O O   . ARG D 4 77  ? -7.556  -40.461 -3.679  1.00 98.60  ? 77  ARG D O   1 
ATOM   5473 C CB  . ARG D 4 77  ? -8.457  -39.185 -1.408  1.00 64.37  ? 77  ARG D CB  1 
ATOM   5474 C CG  . ARG D 4 77  ? -8.807  -38.170 -0.336  1.00 69.74  ? 77  ARG D CG  1 
ATOM   5475 C CD  . ARG D 4 77  ? -10.303 -37.913 -0.269  1.00 71.41  ? 77  ARG D CD  1 
ATOM   5476 N NE  . ARG D 4 77  ? -11.021 -39.002 0.381   1.00 80.14  ? 77  ARG D NE  1 
ATOM   5477 C CZ  . ARG D 4 77  ? -12.338 -39.054 0.524   1.00 74.96  ? 77  ARG D CZ  1 
ATOM   5478 N NH1 . ARG D 4 77  ? -13.123 -38.095 0.059   1.00 61.29  ? 77  ARG D NH1 1 
ATOM   5479 N NH2 . ARG D 4 77  ? -12.883 -40.094 1.148   1.00 79.52  ? 77  ARG D NH2 1 
ATOM   5480 N N   . LEU D 4 78  ? -5.361  -40.124 -3.273  1.00 73.55  ? 78  LEU D N   1 
ATOM   5481 C CA  . LEU D 4 78  ? -4.897  -40.593 -4.575  1.00 74.12  ? 78  LEU D CA  1 
ATOM   5482 C C   . LEU D 4 78  ? -5.446  -41.974 -4.918  1.00 87.98  ? 78  LEU D C   1 
ATOM   5483 O O   . LEU D 4 78  ? -5.110  -42.967 -4.264  1.00 88.32  ? 78  LEU D O   1 
ATOM   5484 C CB  . LEU D 4 78  ? -3.361  -40.609 -4.619  1.00 73.37  ? 78  LEU D CB  1 
ATOM   5485 C CG  . LEU D 4 78  ? -2.591  -39.303 -4.867  1.00 82.03  ? 78  LEU D CG  1 
ATOM   5486 C CD1 . LEU D 4 78  ? -2.855  -38.261 -3.799  1.00 73.52  ? 78  LEU D CD1 1 
ATOM   5487 C CD2 . LEU D 4 78  ? -1.109  -39.578 -4.936  1.00 74.20  ? 78  LEU D CD2 1 
ATOM   5488 N N   . GLU D 4 79  ? -6.291  -42.046 -5.945  1.00 98.92  ? 79  GLU D N   1 
ATOM   5489 C CA  . GLU D 4 79  ? -6.787  -43.326 -6.422  1.00 89.05  ? 79  GLU D CA  1 
ATOM   5490 C C   . GLU D 4 79  ? -5.689  -44.051 -7.198  1.00 91.07  ? 79  GLU D C   1 
ATOM   5491 O O   . GLU D 4 79  ? -4.731  -43.427 -7.660  1.00 89.71  ? 79  GLU D O   1 
ATOM   5492 C CB  . GLU D 4 79  ? -8.022  -43.127 -7.301  1.00 98.63  ? 79  GLU D CB  1 
ATOM   5493 C CG  . GLU D 4 79  ? -9.248  -43.908 -6.840  1.00 93.94  ? 79  GLU D CG  1 
ATOM   5494 C CD  . GLU D 4 79  ? -10.474 -43.642 -7.693  1.00 101.14 ? 79  GLU D CD  1 
ATOM   5495 O OE1 . GLU D 4 79  ? -10.321 -43.423 -8.914  1.00 105.92 ? 79  GLU D OE1 1 
ATOM   5496 O OE2 . GLU D 4 79  ? -11.592 -43.646 -7.138  1.00 94.44  ? 79  GLU D OE2 1 
ATOM   5497 N N   . PRO D 4 80  ? -5.797  -45.377 -7.341  1.00 103.65 ? 80  PRO D N   1 
ATOM   5498 C CA  . PRO D 4 80  ? -4.772  -46.111 -8.104  1.00 101.70 ? 80  PRO D CA  1 
ATOM   5499 C C   . PRO D 4 80  ? -4.598  -45.624 -9.533  1.00 106.10 ? 80  PRO D C   1 
ATOM   5500 O O   . PRO D 4 80  ? -3.495  -45.739 -10.083 1.00 94.19  ? 80  PRO D O   1 
ATOM   5501 C CB  . PRO D 4 80  ? -5.282  -47.557 -8.061  1.00 100.60 ? 80  PRO D CB  1 
ATOM   5502 C CG  . PRO D 4 80  ? -6.040  -47.632 -6.784  1.00 103.83 ? 80  PRO D CG  1 
ATOM   5503 C CD  . PRO D 4 80  ? -6.700  -46.291 -6.619  1.00 111.81 ? 80  PRO D CD  1 
ATOM   5504 N N   . GLU D 4 81  ? -5.646  -45.085 -10.157 1.00 106.78 ? 81  GLU D N   1 
ATOM   5505 C CA  . GLU D 4 81  ? -5.564  -44.600 -11.529 1.00 97.29  ? 81  GLU D CA  1 
ATOM   5506 C C   . GLU D 4 81  ? -5.621  -43.076 -11.619 1.00 94.29  ? 81  GLU D C   1 
ATOM   5507 O O   . GLU D 4 81  ? -5.926  -42.530 -12.684 1.00 99.63  ? 81  GLU D O   1 
ATOM   5508 C CB  . GLU D 4 81  ? -6.668  -45.227 -12.379 1.00 98.25  ? 81  GLU D CB  1 
ATOM   5509 C CG  . GLU D 4 81  ? -6.704  -46.747 -12.302 1.00 93.79  ? 81  GLU D CG  1 
ATOM   5510 C CD  . GLU D 4 81  ? -5.338  -47.374 -12.505 1.00 92.33  ? 81  GLU D CD  1 
ATOM   5511 O OE1 . GLU D 4 81  ? -4.629  -46.972 -13.451 1.00 106.00 ? 81  GLU D OE1 1 
ATOM   5512 O OE2 . GLU D 4 81  ? -4.968  -48.262 -11.708 1.00 89.31  ? 81  GLU D OE2 1 
ATOM   5513 N N   . ASP D 4 82  ? -5.323  -42.379 -10.524 1.00 97.91  ? 82  ASP D N   1 
ATOM   5514 C CA  . ASP D 4 82  ? -5.242  -40.923 -10.497 1.00 84.89  ? 82  ASP D CA  1 
ATOM   5515 C C   . ASP D 4 82  ? -3.935  -40.401 -11.085 1.00 79.36  ? 82  ASP D C   1 
ATOM   5516 O O   . ASP D 4 82  ? -3.685  -39.195 -11.023 1.00 73.67  ? 82  ASP D O   1 
ATOM   5517 C CB  . ASP D 4 82  ? -5.374  -40.419 -9.058  1.00 74.08  ? 82  ASP D CB  1 
ATOM   5518 C CG  . ASP D 4 82  ? -5.942  -39.006 -8.963  1.00 85.64  ? 82  ASP D CG  1 
ATOM   5519 O OD1 . ASP D 4 82  ? -6.460  -38.650 -7.881  1.00 86.24  ? 82  ASP D OD1 1 
ATOM   5520 O OD2 . ASP D 4 82  ? -5.888  -38.266 -9.967  1.00 94.63  ? 82  ASP D OD2 1 
ATOM   5521 N N   . PHE D 4 83  ? -3.092  -41.270 -11.626 1.00 75.88  ? 83  PHE D N   1 
ATOM   5522 C CA  . PHE D 4 83  ? -1.726  -40.913 -11.973 1.00 76.49  ? 83  PHE D CA  1 
ATOM   5523 C C   . PHE D 4 83  ? -1.586  -40.725 -13.479 1.00 63.50  ? 83  PHE D C   1 
ATOM   5524 O O   . PHE D 4 83  ? -1.812  -41.659 -14.258 1.00 61.77  ? 83  PHE D O   1 
ATOM   5525 C CB  . PHE D 4 83  ? -0.769  -41.982 -11.443 1.00 80.61  ? 83  PHE D CB  1 
ATOM   5526 C CG  . PHE D 4 83  ? -0.944  -42.239 -9.984  1.00 89.53  ? 83  PHE D CG  1 
ATOM   5527 C CD1 . PHE D 4 83  ? -1.556  -43.405 -9.545  1.00 96.14  ? 83  PHE D CD1 1 
ATOM   5528 C CD2 . PHE D 4 83  ? -0.520  -41.295 -9.052  1.00 86.70  ? 83  PHE D CD2 1 
ATOM   5529 C CE1 . PHE D 4 83  ? -1.727  -43.645 -8.199  1.00 87.59  ? 83  PHE D CE1 1 
ATOM   5530 C CE2 . PHE D 4 83  ? -0.682  -41.513 -7.710  1.00 78.37  ? 83  PHE D CE2 1 
ATOM   5531 C CZ  . PHE D 4 83  ? -1.289  -42.695 -7.272  1.00 82.37  ? 83  PHE D CZ  1 
ATOM   5532 N N   . ALA D 4 84  ? -1.230  -39.509 -13.875 1.00 66.62  ? 84  ALA D N   1 
ATOM   5533 C CA  . ALA D 4 84  ? -1.033  -39.135 -15.269 1.00 61.75  ? 84  ALA D CA  1 
ATOM   5534 C C   . ALA D 4 84  ? -0.098  -37.930 -15.297 1.00 56.91  ? 84  ALA D C   1 
ATOM   5535 O O   . ALA D 4 84  ? 0.546   -37.600 -14.295 1.00 64.50  ? 84  ALA D O   1 
ATOM   5536 C CB  . ALA D 4 84  ? -2.375  -38.849 -15.951 1.00 46.15  ? 84  ALA D CB  1 
ATOM   5537 N N   . VAL D 4 85  ? -0.015  -37.273 -16.451 1.00 40.38  ? 85  VAL D N   1 
ATOM   5538 C CA  . VAL D 4 85  ? 0.810   -36.082 -16.622 1.00 51.39  ? 85  VAL D CA  1 
ATOM   5539 C C   . VAL D 4 85  ? -0.073  -34.852 -16.465 1.00 58.11  ? 85  VAL D C   1 
ATOM   5540 O O   . VAL D 4 85  ? -1.138  -34.758 -17.088 1.00 67.72  ? 85  VAL D O   1 
ATOM   5541 C CB  . VAL D 4 85  ? 1.520   -36.084 -17.986 1.00 48.97  ? 85  VAL D CB  1 
ATOM   5542 C CG1 . VAL D 4 85  ? 2.424   -34.866 -18.112 1.00 39.38  ? 85  VAL D CG1 1 
ATOM   5543 C CG2 . VAL D 4 85  ? 2.321   -37.364 -18.160 1.00 57.05  ? 85  VAL D CG2 1 
ATOM   5544 N N   . TYR D 4 86  ? 0.368   -33.908 -15.636 1.00 40.74  ? 86  TYR D N   1 
ATOM   5545 C CA  . TYR D 4 86  ? -0.412  -32.725 -15.299 1.00 42.43  ? 86  TYR D CA  1 
ATOM   5546 C C   . TYR D 4 86  ? 0.307   -31.476 -15.791 1.00 38.74  ? 86  TYR D C   1 
ATOM   5547 O O   . TYR D 4 86  ? 1.488   -31.275 -15.490 1.00 46.11  ? 86  TYR D O   1 
ATOM   5548 C CB  . TYR D 4 86  ? -0.657  -32.649 -13.789 1.00 36.80  ? 86  TYR D CB  1 
ATOM   5549 C CG  . TYR D 4 86  ? -1.444  -33.824 -13.251 1.00 40.41  ? 86  TYR D CG  1 
ATOM   5550 C CD1 . TYR D 4 86  ? -0.813  -35.015 -12.917 1.00 44.25  ? 86  TYR D CD1 1 
ATOM   5551 C CD2 . TYR D 4 86  ? -2.820  -33.745 -13.088 1.00 45.16  ? 86  TYR D CD2 1 
ATOM   5552 C CE1 . TYR D 4 86  ? -1.530  -36.093 -12.432 1.00 50.10  ? 86  TYR D CE1 1 
ATOM   5553 C CE2 . TYR D 4 86  ? -3.545  -34.818 -12.603 1.00 52.74  ? 86  TYR D CE2 1 
ATOM   5554 C CZ  . TYR D 4 86  ? -2.895  -35.988 -12.277 1.00 52.26  ? 86  TYR D CZ  1 
ATOM   5555 O OH  . TYR D 4 86  ? -3.613  -37.058 -11.795 1.00 47.17  ? 86  TYR D OH  1 
ATOM   5556 N N   . TYR D 4 87  ? -0.413  -30.641 -16.538 1.00 34.33  ? 87  TYR D N   1 
ATOM   5557 C CA  . TYR D 4 87  ? 0.122   -29.415 -17.111 1.00 46.05  ? 87  TYR D CA  1 
ATOM   5558 C C   . TYR D 4 87  ? -0.574  -28.206 -16.503 1.00 41.05  ? 87  TYR D C   1 
ATOM   5559 O O   . TYR D 4 87  ? -1.741  -28.278 -16.104 1.00 45.98  ? 87  TYR D O   1 
ATOM   5560 C CB  . TYR D 4 87  ? -0.059  -29.377 -18.637 1.00 48.14  ? 87  TYR D CB  1 
ATOM   5561 C CG  . TYR D 4 87  ? 0.703   -30.436 -19.402 1.00 45.25  ? 87  TYR D CG  1 
ATOM   5562 C CD1 . TYR D 4 87  ? 0.162   -31.699 -19.605 1.00 42.85  ? 87  TYR D CD1 1 
ATOM   5563 C CD2 . TYR D 4 87  ? 1.954   -30.165 -19.941 1.00 42.61  ? 87  TYR D CD2 1 
ATOM   5564 C CE1 . TYR D 4 87  ? 0.851   -32.667 -20.312 1.00 52.48  ? 87  TYR D CE1 1 
ATOM   5565 C CE2 . TYR D 4 87  ? 2.652   -31.126 -20.650 1.00 40.52  ? 87  TYR D CE2 1 
ATOM   5566 C CZ  . TYR D 4 87  ? 2.096   -32.375 -20.832 1.00 52.91  ? 87  TYR D CZ  1 
ATOM   5567 O OH  . TYR D 4 87  ? 2.784   -33.335 -21.537 1.00 55.55  ? 87  TYR D OH  1 
ATOM   5568 N N   . CYS D 4 88  ? 0.148   -27.090 -16.439 1.00 38.49  ? 88  CYS D N   1 
ATOM   5569 C CA  . CYS D 4 88  ? -0.419  -25.806 -16.050 1.00 56.26  ? 88  CYS D CA  1 
ATOM   5570 C C   . CYS D 4 88  ? -0.370  -24.864 -17.243 1.00 56.28  ? 88  CYS D C   1 
ATOM   5571 O O   . CYS D 4 88  ? 0.658   -24.765 -17.921 1.00 49.84  ? 88  CYS D O   1 
ATOM   5572 C CB  . CYS D 4 88  ? 0.320   -25.191 -14.855 1.00 63.88  ? 88  CYS D CB  1 
ATOM   5573 S SG  . CYS D 4 88  ? 2.093   -24.869 -15.068 1.00 78.21  ? 88  CYS D SG  1 
ATOM   5574 N N   . GLN D 4 89  ? -1.485  -24.184 -17.502 1.00 54.42  ? 89  GLN D N   1 
ATOM   5575 C CA  . GLN D 4 89  ? -1.606  -23.278 -18.634 1.00 50.73  ? 89  GLN D CA  1 
ATOM   5576 C C   . GLN D 4 89  ? -2.070  -21.916 -18.142 1.00 45.65  ? 89  GLN D C   1 
ATOM   5577 O O   . GLN D 4 89  ? -3.048  -21.823 -17.393 1.00 48.44  ? 89  GLN D O   1 
ATOM   5578 C CB  . GLN D 4 89  ? -2.585  -23.827 -19.677 1.00 42.14  ? 89  GLN D CB  1 
ATOM   5579 C CG  . GLN D 4 89  ? -2.842  -22.887 -20.840 1.00 42.81  ? 89  GLN D CG  1 
ATOM   5580 C CD  . GLN D 4 89  ? -4.306  -22.519 -20.978 1.00 44.37  ? 89  GLN D CD  1 
ATOM   5581 O OE1 . GLN D 4 89  ? -5.185  -23.225 -20.482 1.00 41.76  ? 89  GLN D OE1 1 
ATOM   5582 N NE2 . GLN D 4 89  ? -4.574  -21.406 -21.650 1.00 45.16  ? 89  GLN D NE2 1 
ATOM   5583 N N   . GLN D 4 90  ? -1.368  -20.868 -18.563 1.00 38.18  ? 90  GLN D N   1 
ATOM   5584 C CA  . GLN D 4 90  ? -1.740  -19.498 -18.247 1.00 48.25  ? 90  GLN D CA  1 
ATOM   5585 C C   . GLN D 4 90  ? -2.458  -18.877 -19.437 1.00 56.33  ? 90  GLN D C   1 
ATOM   5586 O O   . GLN D 4 90  ? -2.130  -19.161 -20.593 1.00 56.27  ? 90  GLN D O   1 
ATOM   5587 C CB  . GLN D 4 90  ? -0.511  -18.662 -17.872 1.00 36.49  ? 90  GLN D CB  1 
ATOM   5588 C CG  . GLN D 4 90  ? 0.507   -18.470 -18.993 1.00 34.54  ? 90  GLN D CG  1 
ATOM   5589 C CD  . GLN D 4 90  ? 0.205   -17.265 -19.867 1.00 45.45  ? 90  GLN D CD  1 
ATOM   5590 O OE1 . GLN D 4 90  ? -0.600  -16.406 -19.506 1.00 45.08  ? 90  GLN D OE1 1 
ATOM   5591 N NE2 . GLN D 4 90  ? 0.849   -17.200 -21.027 1.00 44.59  ? 90  GLN D NE2 1 
ATOM   5592 N N   . TYR D 4 91  ? -3.453  -18.036 -19.147 1.00 56.17  ? 91  TYR D N   1 
ATOM   5593 C CA  . TYR D 4 91  ? -4.171  -17.313 -20.190 1.00 55.86  ? 91  TYR D CA  1 
ATOM   5594 C C   . TYR D 4 91  ? -4.287  -15.825 -19.880 1.00 59.55  ? 91  TYR D C   1 
ATOM   5595 O O   . TYR D 4 91  ? -5.136  -15.144 -20.463 1.00 65.57  ? 91  TYR D O   1 
ATOM   5596 C CB  . TYR D 4 91  ? -5.561  -17.914 -20.418 1.00 48.35  ? 91  TYR D CB  1 
ATOM   5597 C CG  . TYR D 4 91  ? -6.329  -18.247 -19.156 1.00 49.11  ? 91  TYR D CG  1 
ATOM   5598 C CD1 . TYR D 4 91  ? -6.239  -19.507 -18.578 1.00 45.06  ? 91  TYR D CD1 1 
ATOM   5599 C CD2 . TYR D 4 91  ? -7.157  -17.309 -18.553 1.00 46.93  ? 91  TYR D CD2 1 
ATOM   5600 C CE1 . TYR D 4 91  ? -6.943  -19.821 -17.431 1.00 44.04  ? 91  TYR D CE1 1 
ATOM   5601 C CE2 . TYR D 4 91  ? -7.866  -17.614 -17.405 1.00 50.56  ? 91  TYR D CE2 1 
ATOM   5602 C CZ  . TYR D 4 91  ? -7.754  -18.871 -16.849 1.00 43.12  ? 91  TYR D CZ  1 
ATOM   5603 O OH  . TYR D 4 91  ? -8.457  -19.179 -15.707 1.00 42.15  ? 91  TYR D OH  1 
ATOM   5604 N N   . GLY D 4 92  ? -3.455  -15.312 -18.971 1.00 60.03  ? 92  GLY D N   1 
ATOM   5605 C CA  . GLY D 4 92  ? -3.489  -13.890 -18.670 1.00 57.80  ? 92  GLY D CA  1 
ATOM   5606 C C   . GLY D 4 92  ? -3.007  -13.029 -19.821 1.00 61.28  ? 92  GLY D C   1 
ATOM   5607 O O   . GLY D 4 92  ? -3.596  -11.985 -20.116 1.00 70.39  ? 92  GLY D O   1 
ATOM   5608 N N   . SER D 4 93  ? -1.935  -13.450 -20.489 1.00 57.13  ? 93  SER D N   1 
ATOM   5609 C CA  . SER D 4 93  ? -1.333  -12.663 -21.554 1.00 56.29  ? 93  SER D CA  1 
ATOM   5610 C C   . SER D 4 93  ? -1.014  -13.555 -22.743 1.00 58.49  ? 93  SER D C   1 
ATOM   5611 O O   . SER D 4 93  ? -0.526  -14.676 -22.578 1.00 62.56  ? 93  SER D O   1 
ATOM   5612 C CB  . SER D 4 93  ? -0.056  -11.959 -21.077 1.00 58.65  ? 93  SER D CB  1 
ATOM   5613 O OG  . SER D 4 93  ? 0.526   -11.194 -22.118 1.00 62.72  ? 93  SER D OG  1 
ATOM   5614 N N   . SER D 4 94  ? -1.290  -13.042 -23.938 1.00 59.22  ? 94  SER D N   1 
ATOM   5615 C CA  . SER D 4 94  ? -1.011  -13.758 -25.174 1.00 50.29  ? 94  SER D CA  1 
ATOM   5616 C C   . SER D 4 94  ? 0.483   -13.695 -25.492 1.00 59.82  ? 94  SER D C   1 
ATOM   5617 O O   . SER D 4 94  ? 1.131   -12.679 -25.229 1.00 63.49  ? 94  SER D O   1 
ATOM   5618 C CB  . SER D 4 94  ? -1.817  -13.161 -26.328 1.00 55.40  ? 94  SER D CB  1 
ATOM   5619 O OG  . SER D 4 94  ? -1.694  -13.940 -27.506 1.00 57.48  ? 94  SER D OG  1 
ATOM   5620 N N   . PRO D 4 95  ? 1.057   -14.765 -26.062 1.00 66.06  ? 95  PRO D N   1 
ATOM   5621 C CA  . PRO D 4 95  ? 0.433   -16.057 -26.392 1.00 50.98  ? 95  PRO D CA  1 
ATOM   5622 C C   . PRO D 4 95  ? 0.210   -16.924 -25.160 1.00 46.43  ? 95  PRO D C   1 
ATOM   5623 O O   . PRO D 4 95  ? 1.037   -16.948 -24.252 1.00 54.00  ? 95  PRO D O   1 
ATOM   5624 C CB  . PRO D 4 95  ? 1.447   -16.705 -27.355 1.00 40.06  ? 95  PRO D CB  1 
ATOM   5625 C CG  . PRO D 4 95  ? 2.380   -15.596 -27.781 1.00 40.92  ? 95  PRO D CG  1 
ATOM   5626 C CD  . PRO D 4 95  ? 2.421   -14.674 -26.603 1.00 53.03  ? 95  PRO D CD  1 
ATOM   5627 N N   . ARG D 4 96  ? -0.909  -17.641 -25.106 1.00 54.75  ? 96  ARG D N   1 
ATOM   5628 C CA  . ARG D 4 96  ? -1.137  -18.581 -24.018 1.00 55.61  ? 96  ARG D CA  1 
ATOM   5629 C C   . ARG D 4 96  ? -0.114  -19.708 -24.081 1.00 49.82  ? 96  ARG D C   1 
ATOM   5630 O O   . ARG D 4 96  ? 0.206   -20.220 -25.158 1.00 48.23  ? 96  ARG D O   1 
ATOM   5631 C CB  . ARG D 4 96  ? -2.556  -19.141 -24.091 1.00 50.10  ? 96  ARG D CB  1 
ATOM   5632 C CG  . ARG D 4 96  ? -3.641  -18.121 -23.784 1.00 50.43  ? 96  ARG D CG  1 
ATOM   5633 C CD  . ARG D 4 96  ? -5.016  -18.707 -24.038 1.00 44.73  ? 96  ARG D CD  1 
ATOM   5634 N NE  . ARG D 4 96  ? -5.301  -18.819 -25.463 1.00 56.50  ? 96  ARG D NE  1 
ATOM   5635 C CZ  . ARG D 4 96  ? -6.222  -19.619 -25.981 1.00 49.46  ? 96  ARG D CZ  1 
ATOM   5636 N NH1 . ARG D 4 96  ? -6.943  -20.426 -25.221 1.00 54.43  ? 96  ARG D NH1 1 
ATOM   5637 N NH2 . ARG D 4 96  ? -6.427  -19.607 -27.296 1.00 40.89  ? 96  ARG D NH2 1 
ATOM   5638 N N   . THR D 4 97  ? 0.408   -20.089 -22.918 1.00 42.14  ? 97  THR D N   1 
ATOM   5639 C CA  . THR D 4 97  ? 1.520   -21.021 -22.839 1.00 42.44  ? 97  THR D CA  1 
ATOM   5640 C C   . THR D 4 97  ? 1.247   -22.087 -21.787 1.00 41.52  ? 97  THR D C   1 
ATOM   5641 O O   . THR D 4 97  ? 0.518   -21.858 -20.817 1.00 43.62  ? 97  THR D O   1 
ATOM   5642 C CB  . THR D 4 97  ? 2.832   -20.292 -22.512 1.00 37.10  ? 97  THR D CB  1 
ATOM   5643 O OG1 . THR D 4 97  ? 2.643   -19.457 -21.363 1.00 49.77  ? 97  THR D OG1 1 
ATOM   5644 C CG2 . THR D 4 97  ? 3.274   -19.432 -23.689 1.00 22.16  ? 97  THR D CG2 1 
ATOM   5645 N N   . PHE D 4 98  ? 1.846   -23.256 -21.993 1.00 44.18  ? 98  PHE D N   1 
ATOM   5646 C CA  . PHE D 4 98  ? 1.771   -24.383 -21.077 1.00 39.98  ? 98  PHE D CA  1 
ATOM   5647 C C   . PHE D 4 98  ? 3.104   -24.546 -20.354 1.00 44.85  ? 98  PHE D C   1 
ATOM   5648 O O   . PHE D 4 98  ? 4.078   -23.835 -20.616 1.00 43.98  ? 98  PHE D O   1 
ATOM   5649 C CB  . PHE D 4 98  ? 1.417   -25.673 -21.823 1.00 37.81  ? 98  PHE D CB  1 
ATOM   5650 C CG  . PHE D 4 98  ? 0.041   -25.682 -22.420 1.00 39.60  ? 98  PHE D CG  1 
ATOM   5651 C CD1 . PHE D 4 98  ? -0.211  -25.050 -23.626 1.00 37.65  ? 98  PHE D CD1 1 
ATOM   5652 C CD2 . PHE D 4 98  ? -0.996  -26.349 -21.788 1.00 41.70  ? 98  PHE D CD2 1 
ATOM   5653 C CE1 . PHE D 4 98  ? -1.476  -25.066 -24.182 1.00 34.11  ? 98  PHE D CE1 1 
ATOM   5654 C CE2 . PHE D 4 98  ? -2.263  -26.369 -22.338 1.00 34.03  ? 98  PHE D CE2 1 
ATOM   5655 C CZ  . PHE D 4 98  ? -2.504  -25.727 -23.537 1.00 34.08  ? 98  PHE D CZ  1 
ATOM   5656 N N   . GLY D 4 99  ? 3.138   -25.506 -19.431 1.00 49.84  ? 99  GLY D N   1 
ATOM   5657 C CA  . GLY D 4 99  ? 4.373   -25.943 -18.824 1.00 44.66  ? 99  GLY D CA  1 
ATOM   5658 C C   . GLY D 4 99  ? 4.883   -27.222 -19.473 1.00 56.70  ? 99  GLY D C   1 
ATOM   5659 O O   . GLY D 4 99  ? 4.199   -27.868 -20.262 1.00 67.38  ? 99  GLY D O   1 
ATOM   5660 N N   . GLN D 4 100 ? 6.117   -27.583 -19.119 1.00 69.48  ? 100 GLN D N   1 
ATOM   5661 C CA  . GLN D 4 100 ? 6.711   -28.803 -19.650 1.00 57.88  ? 100 GLN D CA  1 
ATOM   5662 C C   . GLN D 4 100 ? 6.045   -30.060 -19.109 1.00 54.42  ? 100 GLN D C   1 
ATOM   5663 O O   . GLN D 4 100 ? 6.308   -31.152 -19.625 1.00 60.79  ? 100 GLN D O   1 
ATOM   5664 C CB  . GLN D 4 100 ? 8.209   -28.848 -19.344 1.00 57.13  ? 100 GLN D CB  1 
ATOM   5665 C CG  . GLN D 4 100 ? 8.951   -27.552 -19.619 1.00 63.87  ? 100 GLN D CG  1 
ATOM   5666 C CD  . GLN D 4 100 ? 8.941   -26.614 -18.426 1.00 87.36  ? 100 GLN D CD  1 
ATOM   5667 O OE1 . GLN D 4 100 ? 8.102   -26.736 -17.532 1.00 74.98  ? 100 GLN D OE1 1 
ATOM   5668 N NE2 . GLN D 4 100 ? 9.882   -25.677 -18.402 1.00 70.75  ? 100 GLN D NE2 1 
ATOM   5669 N N   . GLY D 4 101 ? 5.203   -29.937 -18.091 1.00 43.14  ? 101 GLY D N   1 
ATOM   5670 C CA  . GLY D 4 101 ? 4.488   -31.064 -17.538 1.00 38.19  ? 101 GLY D CA  1 
ATOM   5671 C C   . GLY D 4 101 ? 5.130   -31.586 -16.264 1.00 44.05  ? 101 GLY D C   1 
ATOM   5672 O O   . GLY D 4 101 ? 6.293   -31.314 -15.954 1.00 46.17  ? 101 GLY D O   1 
ATOM   5673 N N   . THR D 4 102 ? 4.341   -32.345 -15.508 1.00 34.08  ? 102 THR D N   1 
ATOM   5674 C CA  . THR D 4 102 ? 4.817   -33.010 -14.298 1.00 39.18  ? 102 THR D CA  1 
ATOM   5675 C C   . THR D 4 102 ? 4.218   -34.407 -14.266 1.00 43.77  ? 102 THR D C   1 
ATOM   5676 O O   . THR D 4 102 ? 2.999   -34.561 -14.140 1.00 53.94  ? 102 THR D O   1 
ATOM   5677 C CB  . THR D 4 102 ? 4.444   -32.230 -13.038 1.00 50.37  ? 102 THR D CB  1 
ATOM   5678 O OG1 . THR D 4 102 ? 5.200   -31.014 -12.984 1.00 56.87  ? 102 THR D OG1 1 
ATOM   5679 C CG2 . THR D 4 102 ? 4.737   -33.063 -11.798 1.00 42.54  ? 102 THR D CG2 1 
ATOM   5680 N N   . LYS D 4 103 ? 5.072   -35.418 -14.382 1.00 39.33  ? 103 LYS D N   1 
ATOM   5681 C CA  . LYS D 4 103 ? 4.617   -36.798 -14.381 1.00 54.46  ? 103 LYS D CA  1 
ATOM   5682 C C   . LYS D 4 103 ? 4.261   -37.238 -12.966 1.00 46.52  ? 103 LYS D C   1 
ATOM   5683 O O   . LYS D 4 103 ? 4.793   -36.725 -11.979 1.00 54.62  ? 103 LYS D O   1 
ATOM   5684 C CB  . LYS D 4 103 ? 5.689   -37.714 -14.971 1.00 67.39  ? 103 LYS D CB  1 
ATOM   5685 C CG  . LYS D 4 103 ? 5.143   -38.978 -15.613 1.00 68.51  ? 103 LYS D CG  1 
ATOM   5686 C CD  . LYS D 4 103 ? 6.071   -39.486 -16.707 1.00 67.62  ? 103 LYS D CD  1 
ATOM   5687 C CE  . LYS D 4 103 ? 6.263   -38.435 -17.792 1.00 72.08  ? 103 LYS D CE  1 
ATOM   5688 N NZ  . LYS D 4 103 ? 6.924   -38.993 -19.004 1.00 71.79  ? 103 LYS D NZ  1 
ATOM   5689 N N   . LEU D 4 104 ? 3.344   -38.199 -12.878 1.00 48.00  ? 104 LEU D N   1 
ATOM   5690 C CA  . LEU D 4 104 ? 2.836   -38.676 -11.597 1.00 61.64  ? 104 LEU D CA  1 
ATOM   5691 C C   . LEU D 4 104 ? 2.615   -40.176 -11.705 1.00 70.33  ? 104 LEU D C   1 
ATOM   5692 O O   . LEU D 4 104 ? 1.878   -40.632 -12.585 1.00 69.14  ? 104 LEU D O   1 
ATOM   5693 C CB  . LEU D 4 104 ? 1.540   -37.946 -11.219 1.00 67.69  ? 104 LEU D CB  1 
ATOM   5694 C CG  . LEU D 4 104 ? 1.072   -37.970 -9.763  1.00 64.75  ? 104 LEU D CG  1 
ATOM   5695 C CD1 . LEU D 4 104 ? 2.260   -38.038 -8.830  1.00 58.23  ? 104 LEU D CD1 1 
ATOM   5696 C CD2 . LEU D 4 104 ? 0.244   -36.730 -9.464  1.00 66.52  ? 104 LEU D CD2 1 
ATOM   5697 N N   . GLU D 4 105 ? 3.251   -40.941 -10.818 1.00 70.11  ? 105 GLU D N   1 
ATOM   5698 C CA  . GLU D 4 105 ? 3.229   -42.395 -10.893 1.00 75.76  ? 105 GLU D CA  1 
ATOM   5699 C C   . GLU D 4 105 ? 2.828   -42.988 -9.548  1.00 76.69  ? 105 GLU D C   1 
ATOM   5700 O O   . GLU D 4 105 ? 2.935   -42.342 -8.503  1.00 74.48  ? 105 GLU D O   1 
ATOM   5701 C CB  . GLU D 4 105 ? 4.597   -42.951 -11.332 1.00 79.89  ? 105 GLU D CB  1 
ATOM   5702 C CG  . GLU D 4 105 ? 5.540   -43.326 -10.189 1.00 88.18  ? 105 GLU D CG  1 
ATOM   5703 C CD  . GLU D 4 105 ? 6.977   -43.505 -10.647 1.00 82.40  ? 105 GLU D CD  1 
ATOM   5704 O OE1 . GLU D 4 105 ? 7.211   -43.488 -11.877 1.00 88.60  ? 105 GLU D OE1 1 
ATOM   5705 O OE2 . GLU D 4 105 ? 7.863   -43.664 -9.775  1.00 87.04  ? 105 GLU D OE2 1 
ATOM   5706 N N   . ILE D 4 106 ? 2.375   -44.239 -9.589  1.00 77.66  ? 106 ILE D N   1 
ATOM   5707 C CA  . ILE D 4 106 ? 1.947   -44.967 -8.398  1.00 78.53  ? 106 ILE D CA  1 
ATOM   5708 C C   . ILE D 4 106 ? 3.099   -45.815 -7.874  1.00 90.77  ? 106 ILE D C   1 
ATOM   5709 O O   . ILE D 4 106 ? 3.760   -46.528 -8.640  1.00 106.56 ? 106 ILE D O   1 
ATOM   5710 C CB  . ILE D 4 106 ? 0.717   -45.840 -8.702  1.00 83.30  ? 106 ILE D CB  1 
ATOM   5711 C CG1 . ILE D 4 106 ? 0.620   -47.010 -7.718  1.00 89.89  ? 106 ILE D CG1 1 
ATOM   5712 C CG2 . ILE D 4 106 ? 0.719   -46.312 -10.155 1.00 90.41  ? 106 ILE D CG2 1 
ATOM   5713 C CD1 . ILE D 4 106 ? -0.681  -47.778 -7.800  1.00 78.26  ? 106 ILE D CD1 1 
ATOM   5714 N N   . LYS D 4 107 ? 3.350   -45.726 -6.570  1.00 83.54  ? 107 LYS D N   1 
ATOM   5715 C CA  . LYS D 4 107 ? 4.316   -46.590 -5.906  1.00 85.42  ? 107 LYS D CA  1 
ATOM   5716 C C   . LYS D 4 107 ? 3.581   -47.789 -5.318  1.00 99.84  ? 107 LYS D C   1 
ATOM   5717 O O   . LYS D 4 107 ? 2.776   -47.642 -4.393  1.00 106.56 ? 107 LYS D O   1 
ATOM   5718 C CB  . LYS D 4 107 ? 5.073   -45.821 -4.828  1.00 82.01  ? 107 LYS D CB  1 
ATOM   5719 C CG  . LYS D 4 107 ? 5.899   -46.712 -3.924  1.00 90.81  ? 107 LYS D CG  1 
ATOM   5720 C CD  . LYS D 4 107 ? 6.973   -45.940 -3.178  1.00 89.81  ? 107 LYS D CD  1 
ATOM   5721 C CE  . LYS D 4 107 ? 8.067   -45.469 -4.125  1.00 84.64  ? 107 LYS D CE  1 
ATOM   5722 N NZ  . LYS D 4 107 ? 9.310   -45.059 -3.413  1.00 72.69  ? 107 LYS D NZ  1 
ATOM   5723 N N   . ARG D 4 108 ? 3.845   -48.968 -5.866  1.00 94.22  ? 108 ARG D N   1 
ATOM   5724 C CA  . ARG D 4 108 ? 3.328   -50.226 -5.358  1.00 79.77  ? 108 ARG D CA  1 
ATOM   5725 C C   . ARG D 4 108 ? 4.469   -51.024 -4.733  1.00 77.40  ? 108 ARG D C   1 
ATOM   5726 O O   . ARG D 4 108 ? 5.601   -50.542 -4.604  1.00 78.67  ? 108 ARG D O   1 
ATOM   5727 C CB  . ARG D 4 108 ? 2.622   -51.010 -6.469  1.00 78.80  ? 108 ARG D CB  1 
ATOM   5728 C CG  . ARG D 4 108 ? 3.545   -51.769 -7.435  1.00 88.23  ? 108 ARG D CG  1 
ATOM   5729 C CD  . ARG D 4 108 ? 2.942   -53.121 -7.850  1.00 75.26  ? 108 ARG D CD  1 
ATOM   5730 N NE  . ARG D 4 108 ? 3.376   -54.228 -7.002  1.00 60.27  ? 108 ARG D NE  1 
ATOM   5731 C CZ  . ARG D 4 108 ? 3.150   -55.508 -7.269  1.00 69.85  ? 108 ARG D CZ  1 
ATOM   5732 N NH1 . ARG D 4 108 ? 2.491   -55.881 -8.353  1.00 53.80  ? 108 ARG D NH1 1 
ATOM   5733 N NH2 . ARG D 4 108 ? 3.601   -56.437 -6.430  1.00 75.96  ? 108 ARG D NH2 1 
ATOM   5734 N N   . THR D 4 109 ? 4.162   -52.254 -4.336  1.00 78.32  ? 109 THR D N   1 
ATOM   5735 C CA  . THR D 4 109 ? 5.171   -53.149 -3.791  1.00 76.22  ? 109 THR D CA  1 
ATOM   5736 C C   . THR D 4 109 ? 6.192   -53.521 -4.860  1.00 81.22  ? 109 THR D C   1 
ATOM   5737 O O   . THR D 4 109 ? 5.897   -53.535 -6.059  1.00 76.51  ? 109 THR D O   1 
ATOM   5738 C CB  . THR D 4 109 ? 4.517   -54.415 -3.242  1.00 73.65  ? 109 THR D CB  1 
ATOM   5739 O OG1 . THR D 4 109 ? 5.070   -55.562 -3.898  1.00 81.48  ? 109 THR D OG1 1 
ATOM   5740 C CG2 . THR D 4 109 ? 3.012   -54.377 -3.483  1.00 57.55  ? 109 THR D CG2 1 
ATOM   5741 N N   . VAL D 4 110 ? 7.410   -53.820 -4.408  1.00 78.66  ? 110 VAL D N   1 
ATOM   5742 C CA  . VAL D 4 110 ? 8.479   -54.226 -5.312  1.00 72.40  ? 110 VAL D CA  1 
ATOM   5743 C C   . VAL D 4 110 ? 8.161   -55.595 -5.895  1.00 68.78  ? 110 VAL D C   1 
ATOM   5744 O O   . VAL D 4 110 ? 7.789   -56.528 -5.170  1.00 67.76  ? 110 VAL D O   1 
ATOM   5745 C CB  . VAL D 4 110 ? 9.827   -54.238 -4.577  1.00 66.72  ? 110 VAL D CB  1 
ATOM   5746 C CG1 . VAL D 4 110 ? 10.956  -54.534 -5.549  1.00 48.68  ? 110 VAL D CG1 1 
ATOM   5747 C CG2 . VAL D 4 110 ? 10.055  -52.912 -3.864  1.00 71.38  ? 110 VAL D CG2 1 
ATOM   5748 N N   . ALA D 4 111 ? 8.304   -55.722 -7.212  1.00 70.36  ? 111 ALA D N   1 
ATOM   5749 C CA  . ALA D 4 111 ? 8.043   -56.970 -7.914  1.00 77.72  ? 111 ALA D CA  1 
ATOM   5750 C C   . ALA D 4 111 ? 9.241   -57.320 -8.783  1.00 73.97  ? 111 ALA D C   1 
ATOM   5751 O O   . ALA D 4 111 ? 9.720   -56.481 -9.553  1.00 69.54  ? 111 ALA D O   1 
ATOM   5752 C CB  . ALA D 4 111 ? 6.777   -56.866 -8.768  1.00 68.29  ? 111 ALA D CB  1 
ATOM   5753 N N   . ALA D 4 112 ? 9.720   -58.554 -8.656  1.00 65.20  ? 112 ALA D N   1 
ATOM   5754 C CA  . ALA D 4 112 ? 10.826  -59.013 -9.478  1.00 62.23  ? 112 ALA D CA  1 
ATOM   5755 C C   . ALA D 4 112 ? 10.370  -59.211 -10.923 1.00 70.14  ? 112 ALA D C   1 
ATOM   5756 O O   . ALA D 4 112 ? 9.225   -59.596 -11.175 1.00 66.06  ? 112 ALA D O   1 
ATOM   5757 C CB  . ALA D 4 112 ? 11.395  -60.318 -8.930  1.00 60.79  ? 112 ALA D CB  1 
ATOM   5758 N N   . PRO D 4 113 ? 11.245  -58.950 -11.890 1.00 68.83  ? 113 PRO D N   1 
ATOM   5759 C CA  . PRO D 4 113 ? 10.876  -59.150 -13.293 1.00 58.51  ? 113 PRO D CA  1 
ATOM   5760 C C   . PRO D 4 113 ? 10.955  -60.609 -13.710 1.00 57.41  ? 113 PRO D C   1 
ATOM   5761 O O   . PRO D 4 113 ? 11.798  -61.377 -13.240 1.00 53.74  ? 113 PRO D O   1 
ATOM   5762 C CB  . PRO D 4 113 ? 11.913  -58.310 -14.048 1.00 53.34  ? 113 PRO D CB  1 
ATOM   5763 C CG  . PRO D 4 113 ? 13.111  -58.338 -13.165 1.00 55.53  ? 113 PRO D CG  1 
ATOM   5764 C CD  . PRO D 4 113 ? 12.589  -58.362 -11.749 1.00 65.46  ? 113 PRO D CD  1 
ATOM   5765 N N   . SER D 4 114 ? 10.050  -60.982 -14.611 1.00 50.12  ? 114 SER D N   1 
ATOM   5766 C CA  . SER D 4 114 ? 10.072  -62.287 -15.261 1.00 57.88  ? 114 SER D CA  1 
ATOM   5767 C C   . SER D 4 114 ? 10.780  -62.120 -16.601 1.00 63.39  ? 114 SER D C   1 
ATOM   5768 O O   . SER D 4 114 ? 10.257  -61.464 -17.508 1.00 62.39  ? 114 SER D O   1 
ATOM   5769 C CB  . SER D 4 114 ? 8.659   -62.834 -15.441 1.00 57.74  ? 114 SER D CB  1 
ATOM   5770 O OG  . SER D 4 114 ? 8.012   -63.003 -14.192 1.00 67.55  ? 114 SER D OG  1 
ATOM   5771 N N   . VAL D 4 115 ? 11.965  -62.710 -16.724 1.00 48.30  ? 115 VAL D N   1 
ATOM   5772 C CA  . VAL D 4 115 ? 12.837  -62.497 -17.872 1.00 46.64  ? 115 VAL D CA  1 
ATOM   5773 C C   . VAL D 4 115 ? 12.668  -63.648 -18.852 1.00 58.80  ? 115 VAL D C   1 
ATOM   5774 O O   . VAL D 4 115 ? 12.819  -64.819 -18.483 1.00 60.41  ? 115 VAL D O   1 
ATOM   5775 C CB  . VAL D 4 115 ? 14.306  -62.354 -17.440 1.00 49.87  ? 115 VAL D CB  1 
ATOM   5776 C CG1 . VAL D 4 115 ? 15.230  -62.537 -18.633 1.00 49.62  ? 115 VAL D CG1 1 
ATOM   5777 C CG2 . VAL D 4 115 ? 14.530  -60.995 -16.801 1.00 59.65  ? 115 VAL D CG2 1 
ATOM   5778 N N   . PHE D 4 116 ? 12.351  -63.312 -20.101 1.00 57.74  ? 116 PHE D N   1 
ATOM   5779 C CA  . PHE D 4 116 ? 12.241  -64.279 -21.182 1.00 57.96  ? 116 PHE D CA  1 
ATOM   5780 C C   . PHE D 4 116 ? 13.038  -63.778 -22.376 1.00 57.12  ? 116 PHE D C   1 
ATOM   5781 O O   . PHE D 4 116 ? 13.063  -62.575 -22.655 1.00 58.98  ? 116 PHE D O   1 
ATOM   5782 C CB  . PHE D 4 116 ? 10.780  -64.506 -21.583 1.00 59.79  ? 116 PHE D CB  1 
ATOM   5783 C CG  . PHE D 4 116 ? 9.841   -64.624 -20.417 1.00 63.93  ? 116 PHE D CG  1 
ATOM   5784 C CD1 . PHE D 4 116 ? 9.934   -65.691 -19.539 1.00 69.69  ? 116 PHE D CD1 1 
ATOM   5785 C CD2 . PHE D 4 116 ? 8.859   -63.672 -20.204 1.00 66.63  ? 116 PHE D CD2 1 
ATOM   5786 C CE1 . PHE D 4 116 ? 9.069   -65.801 -18.466 1.00 73.06  ? 116 PHE D CE1 1 
ATOM   5787 C CE2 . PHE D 4 116 ? 7.988   -63.778 -19.136 1.00 64.67  ? 116 PHE D CE2 1 
ATOM   5788 C CZ  . PHE D 4 116 ? 8.094   -64.844 -18.265 1.00 56.25  ? 116 PHE D CZ  1 
ATOM   5789 N N   . ILE D 4 117 ? 13.689  -64.702 -23.077 1.00 52.19  ? 117 ILE D N   1 
ATOM   5790 C CA  . ILE D 4 117 ? 14.508  -64.372 -24.236 1.00 49.92  ? 117 ILE D CA  1 
ATOM   5791 C C   . ILE D 4 117 ? 13.977  -65.143 -25.437 1.00 50.86  ? 117 ILE D C   1 
ATOM   5792 O O   . ILE D 4 117 ? 13.457  -66.256 -25.305 1.00 48.47  ? 117 ILE D O   1 
ATOM   5793 C CB  . ILE D 4 117 ? 16.004  -64.674 -23.983 1.00 48.25  ? 117 ILE D CB  1 
ATOM   5794 C CG1 . ILE D 4 117 ? 16.883  -64.007 -25.044 1.00 40.22  ? 117 ILE D CG1 1 
ATOM   5795 C CG2 . ILE D 4 117 ? 16.257  -66.175 -23.930 1.00 48.62  ? 117 ILE D CG2 1 
ATOM   5796 C CD1 . ILE D 4 117 ? 18.363  -64.054 -24.724 1.00 36.78  ? 117 ILE D CD1 1 
ATOM   5797 N N   . PHE D 4 118 ? 14.089  -64.531 -26.615 1.00 47.08  ? 118 PHE D N   1 
ATOM   5798 C CA  . PHE D 4 118 ? 13.561  -65.110 -27.847 1.00 45.93  ? 118 PHE D CA  1 
ATOM   5799 C C   . PHE D 4 118 ? 14.637  -65.082 -28.923 1.00 45.73  ? 118 PHE D C   1 
ATOM   5800 O O   . PHE D 4 118 ? 15.154  -63.994 -29.251 1.00 50.96  ? 118 PHE D O   1 
ATOM   5801 C CB  . PHE D 4 118 ? 12.311  -64.361 -28.316 1.00 52.98  ? 118 PHE D CB  1 
ATOM   5802 C CG  . PHE D 4 118 ? 11.182  -64.383 -27.328 1.00 62.18  ? 118 PHE D CG  1 
ATOM   5803 C CD1 . PHE D 4 118 ? 10.606  -65.582 -26.941 1.00 65.78  ? 118 PHE D CD1 1 
ATOM   5804 C CD2 . PHE D 4 118 ? 10.685  -63.205 -26.796 1.00 61.39  ? 118 PHE D CD2 1 
ATOM   5805 C CE1 . PHE D 4 118 ? 9.563   -65.606 -26.034 1.00 67.15  ? 118 PHE D CE1 1 
ATOM   5806 C CE2 . PHE D 4 118 ? 9.641   -63.222 -25.890 1.00 69.09  ? 118 PHE D CE2 1 
ATOM   5807 C CZ  . PHE D 4 118 ? 9.079   -64.424 -25.509 1.00 63.04  ? 118 PHE D CZ  1 
ATOM   5808 N N   . PRO D 4 119 ? 15.011  -66.225 -29.491 1.00 43.39  ? 119 PRO D N   1 
ATOM   5809 C CA  . PRO D 4 119 ? 15.915  -66.229 -30.646 1.00 49.31  ? 119 PRO D CA  1 
ATOM   5810 C C   . PRO D 4 119 ? 15.224  -65.653 -31.868 1.00 47.59  ? 119 PRO D C   1 
ATOM   5811 O O   . PRO D 4 119 ? 13.987  -65.672 -31.954 1.00 52.10  ? 119 PRO D O   1 
ATOM   5812 C CB  . PRO D 4 119 ? 16.237  -67.720 -30.841 1.00 36.93  ? 119 PRO D CB  1 
ATOM   5813 C CG  . PRO D 4 119 ? 15.869  -68.374 -29.543 1.00 36.49  ? 119 PRO D CG  1 
ATOM   5814 C CD  . PRO D 4 119 ? 14.713  -67.586 -29.017 1.00 46.33  ? 119 PRO D CD  1 
ATOM   5815 N N   . PRO D 4 120 ? 15.980  -65.118 -32.827 1.00 47.84  ? 120 PRO D N   1 
ATOM   5816 C CA  . PRO D 4 120 ? 15.354  -64.635 -34.063 1.00 53.11  ? 120 PRO D CA  1 
ATOM   5817 C C   . PRO D 4 120 ? 14.679  -65.772 -34.814 1.00 57.48  ? 120 PRO D C   1 
ATOM   5818 O O   . PRO D 4 120 ? 15.168  -66.903 -34.841 1.00 52.38  ? 120 PRO D O   1 
ATOM   5819 C CB  . PRO D 4 120 ? 16.529  -64.050 -34.854 1.00 49.86  ? 120 PRO D CB  1 
ATOM   5820 C CG  . PRO D 4 120 ? 17.728  -64.735 -34.311 1.00 43.64  ? 120 PRO D CG  1 
ATOM   5821 C CD  . PRO D 4 120 ? 17.444  -64.965 -32.855 1.00 52.80  ? 120 PRO D CD  1 
ATOM   5822 N N   . SER D 4 121 ? 13.539  -65.458 -35.422 1.00 60.05  ? 121 SER D N   1 
ATOM   5823 C CA  . SER D 4 121 ? 12.794  -66.454 -36.175 1.00 66.48  ? 121 SER D CA  1 
ATOM   5824 C C   . SER D 4 121 ? 13.564  -66.872 -37.422 1.00 67.57  ? 121 SER D C   1 
ATOM   5825 O O   . SER D 4 121 ? 14.326  -66.093 -38.000 1.00 53.76  ? 121 SER D O   1 
ATOM   5826 C CB  . SER D 4 121 ? 11.421  -65.908 -36.568 1.00 66.92  ? 121 SER D CB  1 
ATOM   5827 O OG  . SER D 4 121 ? 10.698  -65.480 -35.428 1.00 65.37  ? 121 SER D OG  1 
ATOM   5828 N N   . ASP D 4 122 ? 13.364  -68.128 -37.828 1.00 72.20  ? 122 ASP D N   1 
ATOM   5829 C CA  . ASP D 4 122 ? 13.951  -68.593 -39.080 1.00 75.82  ? 122 ASP D CA  1 
ATOM   5830 C C   . ASP D 4 122 ? 13.405  -67.811 -40.265 1.00 68.33  ? 122 ASP D C   1 
ATOM   5831 O O   . ASP D 4 122 ? 14.122  -67.588 -41.249 1.00 54.71  ? 122 ASP D O   1 
ATOM   5832 C CB  . ASP D 4 122 ? 13.690  -70.089 -39.261 1.00 65.00  ? 122 ASP D CB  1 
ATOM   5833 C CG  . ASP D 4 122 ? 14.948  -70.862 -39.604 1.00 83.48  ? 122 ASP D CG  1 
ATOM   5834 O OD1 . ASP D 4 122 ? 16.055  -70.320 -39.402 1.00 79.52  ? 122 ASP D OD1 1 
ATOM   5835 O OD2 . ASP D 4 122 ? 14.829  -72.011 -40.080 1.00 104.61 ? 122 ASP D OD2 1 
ATOM   5836 N N   . GLU D 4 123 ? 12.143  -67.383 -40.186 1.00 60.11  ? 123 GLU D N   1 
ATOM   5837 C CA  . GLU D 4 123 ? 11.572  -66.540 -41.231 1.00 70.72  ? 123 GLU D CA  1 
ATOM   5838 C C   . GLU D 4 123 ? 12.318  -65.216 -41.337 1.00 71.59  ? 123 GLU D C   1 
ATOM   5839 O O   . GLU D 4 123 ? 12.594  -64.736 -42.443 1.00 65.74  ? 123 GLU D O   1 
ATOM   5840 C CB  . GLU D 4 123 ? 10.089  -66.302 -40.948 1.00 71.65  ? 123 GLU D CB  1 
ATOM   5841 C CG  . GLU D 4 123 ? 9.422   -65.296 -41.871 1.00 75.85  ? 123 GLU D CG  1 
ATOM   5842 C CD  . GLU D 4 123 ? 7.992   -64.994 -41.462 1.00 86.01  ? 123 GLU D CD  1 
ATOM   5843 O OE1 . GLU D 4 123 ? 7.463   -65.701 -40.578 1.00 86.58  ? 123 GLU D OE1 1 
ATOM   5844 O OE2 . GLU D 4 123 ? 7.399   -64.048 -42.022 1.00 82.18  ? 123 GLU D OE2 1 
ATOM   5845 N N   . GLN D 4 124 ? 12.653  -64.611 -40.195 1.00 66.75  ? 124 GLN D N   1 
ATOM   5846 C CA  . GLN D 4 124 ? 13.377  -63.345 -40.217 1.00 61.02  ? 124 GLN D CA  1 
ATOM   5847 C C   . GLN D 4 124 ? 14.801  -63.531 -40.727 1.00 61.56  ? 124 GLN D C   1 
ATOM   5848 O O   . GLN D 4 124 ? 15.345  -62.649 -41.403 1.00 46.03  ? 124 GLN D O   1 
ATOM   5849 C CB  . GLN D 4 124 ? 13.391  -62.716 -38.823 1.00 59.96  ? 124 GLN D CB  1 
ATOM   5850 C CG  . GLN D 4 124 ? 13.908  -61.290 -38.811 1.00 62.11  ? 124 GLN D CG  1 
ATOM   5851 C CD  . GLN D 4 124 ? 14.433  -60.867 -37.454 1.00 50.74  ? 124 GLN D CD  1 
ATOM   5852 O OE1 . GLN D 4 124 ? 14.250  -61.566 -36.455 1.00 50.28  ? 124 GLN D OE1 1 
ATOM   5853 N NE2 . GLN D 4 124 ? 15.099  -59.719 -37.412 1.00 38.59  ? 124 GLN D NE2 1 
ATOM   5854 N N   . LEU D 4 125 ? 15.423  -64.668 -40.403 1.00 67.68  ? 125 LEU D N   1 
ATOM   5855 C CA  . LEU D 4 125 ? 16.799  -64.910 -40.826 1.00 63.82  ? 125 LEU D CA  1 
ATOM   5856 C C   . LEU D 4 125 ? 16.925  -64.964 -42.343 1.00 67.68  ? 125 LEU D C   1 
ATOM   5857 O O   . LEU D 4 125 ? 17.955  -64.557 -42.895 1.00 60.36  ? 125 LEU D O   1 
ATOM   5858 C CB  . LEU D 4 125 ? 17.320  -66.205 -40.202 1.00 63.23  ? 125 LEU D CB  1 
ATOM   5859 C CG  . LEU D 4 125 ? 17.580  -66.167 -38.696 1.00 57.92  ? 125 LEU D CG  1 
ATOM   5860 C CD1 . LEU D 4 125 ? 17.952  -67.549 -38.184 1.00 56.37  ? 125 LEU D CD1 1 
ATOM   5861 C CD2 . LEU D 4 125 ? 18.675  -65.164 -38.376 1.00 48.92  ? 125 LEU D CD2 1 
ATOM   5862 N N   . LYS D 4 126 ? 15.895  -65.460 -43.034 1.00 74.66  ? 126 LYS D N   1 
ATOM   5863 C CA  . LYS D 4 126 ? 15.937  -65.487 -44.493 1.00 72.89  ? 126 LYS D CA  1 
ATOM   5864 C C   . LYS D 4 126 ? 15.989  -64.081 -45.075 1.00 68.26  ? 126 LYS D C   1 
ATOM   5865 O O   . LYS D 4 126 ? 16.522  -63.883 -46.173 1.00 70.58  ? 126 LYS D O   1 
ATOM   5866 C CB  . LYS D 4 126 ? 14.733  -66.251 -45.044 1.00 68.50  ? 126 LYS D CB  1 
ATOM   5867 C CG  . LYS D 4 126 ? 14.659  -67.700 -44.590 1.00 65.62  ? 126 LYS D CG  1 
ATOM   5868 C CD  . LYS D 4 126 ? 13.824  -68.536 -45.544 1.00 68.18  ? 126 LYS D CD  1 
ATOM   5869 C CE  . LYS D 4 126 ? 14.450  -68.569 -46.930 1.00 71.13  ? 126 LYS D CE  1 
ATOM   5870 N NZ  . LYS D 4 126 ? 13.709  -69.463 -47.861 1.00 64.26  ? 126 LYS D NZ  1 
ATOM   5871 N N   . SER D 4 127 ? 15.446  -63.094 -44.358 1.00 69.53  ? 127 SER D N   1 
ATOM   5872 C CA  . SER D 4 127 ? 15.544  -61.707 -44.795 1.00 65.35  ? 127 SER D CA  1 
ATOM   5873 C C   . SER D 4 127 ? 16.966  -61.172 -44.708 1.00 63.30  ? 127 SER D C   1 
ATOM   5874 O O   . SER D 4 127 ? 17.276  -60.163 -45.351 1.00 68.64  ? 127 SER D O   1 
ATOM   5875 C CB  . SER D 4 127 ? 14.607  -60.828 -43.966 1.00 57.81  ? 127 SER D CB  1 
ATOM   5876 O OG  . SER D 4 127 ? 14.852  -59.453 -44.206 1.00 61.04  ? 127 SER D OG  1 
ATOM   5877 N N   . GLY D 4 128 ? 17.834  -61.820 -43.938 1.00 61.36  ? 128 GLY D N   1 
ATOM   5878 C CA  . GLY D 4 128 ? 19.191  -61.359 -43.747 1.00 61.42  ? 128 GLY D CA  1 
ATOM   5879 C C   . GLY D 4 128 ? 19.429  -60.546 -42.495 1.00 61.07  ? 128 GLY D C   1 
ATOM   5880 O O   . GLY D 4 128 ? 20.507  -59.955 -42.360 1.00 56.53  ? 128 GLY D O   1 
ATOM   5881 N N   . THR D 4 129 ? 18.462  -60.493 -41.581 1.00 53.23  ? 129 THR D N   1 
ATOM   5882 C CA  . THR D 4 129 ? 18.580  -59.738 -40.342 1.00 52.93  ? 129 THR D CA  1 
ATOM   5883 C C   . THR D 4 129 ? 18.131  -60.607 -39.177 1.00 54.68  ? 129 THR D C   1 
ATOM   5884 O O   . THR D 4 129 ? 17.108  -61.292 -39.263 1.00 51.47  ? 129 THR D O   1 
ATOM   5885 C CB  . THR D 4 129 ? 17.745  -58.447 -40.396 1.00 46.43  ? 129 THR D CB  1 
ATOM   5886 O OG1 . THR D 4 129 ? 18.309  -57.551 -41.362 1.00 49.52  ? 129 THR D OG1 1 
ATOM   5887 C CG2 . THR D 4 129 ? 17.710  -57.762 -39.037 1.00 50.37  ? 129 THR D CG2 1 
ATOM   5888 N N   . ALA D 4 130 ? 18.903  -60.581 -38.094 1.00 57.94  ? 130 ALA D N   1 
ATOM   5889 C CA  . ALA D 4 130 ? 18.602  -61.339 -36.887 1.00 46.26  ? 130 ALA D CA  1 
ATOM   5890 C C   . ALA D 4 130 ? 18.278  -60.379 -35.751 1.00 47.29  ? 130 ALA D C   1 
ATOM   5891 O O   . ALA D 4 130 ? 19.011  -59.410 -35.523 1.00 46.51  ? 130 ALA D O   1 
ATOM   5892 C CB  . ALA D 4 130 ? 19.774  -62.240 -36.499 1.00 48.91  ? 130 ALA D CB  1 
ATOM   5893 N N   . SER D 4 131 ? 17.183  -60.650 -35.043 1.00 36.00  ? 131 SER D N   1 
ATOM   5894 C CA  . SER D 4 131 ? 16.758  -59.837 -33.910 1.00 26.75  ? 131 SER D CA  1 
ATOM   5895 C C   . SER D 4 131 ? 16.564  -60.739 -32.703 1.00 38.80  ? 131 SER D C   1 
ATOM   5896 O O   . SER D 4 131 ? 15.772  -61.687 -32.755 1.00 52.03  ? 131 SER D O   1 
ATOM   5897 C CB  . SER D 4 131 ? 15.465  -59.079 -34.225 1.00 28.62  ? 131 SER D CB  1 
ATOM   5898 O OG  . SER D 4 131 ? 15.622  -58.246 -35.361 1.00 52.89  ? 131 SER D OG  1 
ATOM   5899 N N   . VAL D 4 132 ? 17.274  -60.441 -31.619 1.00 40.80  ? 132 VAL D N   1 
ATOM   5900 C CA  . VAL D 4 132 ? 17.134  -61.153 -30.353 1.00 42.22  ? 132 VAL D CA  1 
ATOM   5901 C C   . VAL D 4 132 ? 16.437  -60.223 -29.373 1.00 46.98  ? 132 VAL D C   1 
ATOM   5902 O O   . VAL D 4 132 ? 16.880  -59.087 -29.166 1.00 51.51  ? 132 VAL D O   1 
ATOM   5903 C CB  . VAL D 4 132 ? 18.496  -61.613 -29.806 1.00 38.50  ? 132 VAL D CB  1 
ATOM   5904 C CG1 . VAL D 4 132 ? 18.307  -62.429 -28.537 1.00 35.73  ? 132 VAL D CG1 1 
ATOM   5905 C CG2 . VAL D 4 132 ? 19.249  -62.414 -30.856 1.00 36.42  ? 132 VAL D CG2 1 
ATOM   5906 N N   . VAL D 4 133 ? 15.349  -60.700 -28.774 1.00 35.73  ? 133 VAL D N   1 
ATOM   5907 C CA  . VAL D 4 133 ? 14.500  -59.887 -27.913 1.00 39.57  ? 133 VAL D CA  1 
ATOM   5908 C C   . VAL D 4 133 ? 14.529  -60.464 -26.506 1.00 43.54  ? 133 VAL D C   1 
ATOM   5909 O O   . VAL D 4 133 ? 14.319  -61.668 -26.317 1.00 51.61  ? 133 VAL D O   1 
ATOM   5910 C CB  . VAL D 4 133 ? 13.057  -59.815 -28.443 1.00 34.75  ? 133 VAL D CB  1 
ATOM   5911 C CG1 . VAL D 4 133 ? 12.167  -59.064 -27.465 1.00 38.71  ? 133 VAL D CG1 1 
ATOM   5912 C CG2 . VAL D 4 133 ? 13.029  -59.153 -29.811 1.00 32.60  ? 133 VAL D CG2 1 
ATOM   5913 N N   . CYS D 4 134 ? 14.791  -59.605 -25.525 1.00 42.52  ? 134 CYS D N   1 
ATOM   5914 C CA  . CYS D 4 134 ? 14.744  -59.965 -24.115 1.00 41.55  ? 134 CYS D CA  1 
ATOM   5915 C C   . CYS D 4 134 ? 13.583  -59.228 -23.464 1.00 44.25  ? 134 CYS D C   1 
ATOM   5916 O O   . CYS D 4 134 ? 13.453  -58.008 -23.617 1.00 46.74  ? 134 CYS D O   1 
ATOM   5917 C CB  . CYS D 4 134 ? 16.061  -59.619 -23.418 1.00 49.52  ? 134 CYS D CB  1 
ATOM   5918 S SG  . CYS D 4 134 ? 16.246  -60.325 -21.768 1.00 61.30  ? 134 CYS D SG  1 
ATOM   5919 N N   . LEU D 4 135 ? 12.742  -59.965 -22.746 1.00 49.23  ? 135 LEU D N   1 
ATOM   5920 C CA  . LEU D 4 135 ? 11.507  -59.434 -22.186 1.00 41.14  ? 135 LEU D CA  1 
ATOM   5921 C C   . LEU D 4 135 ? 11.593  -59.394 -20.667 1.00 40.49  ? 135 LEU D C   1 
ATOM   5922 O O   . LEU D 4 135 ? 11.897  -60.407 -20.030 1.00 49.41  ? 135 LEU D O   1 
ATOM   5923 C CB  . LEU D 4 135 ? 10.307  -60.277 -22.625 1.00 57.85  ? 135 LEU D CB  1 
ATOM   5924 C CG  . LEU D 4 135 ? 8.969   -60.024 -21.925 1.00 52.08  ? 135 LEU D CG  1 
ATOM   5925 C CD1 . LEU D 4 135 ? 8.538   -58.577 -22.075 1.00 53.51  ? 135 LEU D CD1 1 
ATOM   5926 C CD2 . LEU D 4 135 ? 7.901   -60.959 -22.470 1.00 50.95  ? 135 LEU D CD2 1 
ATOM   5927 N N   . LEU D 4 136 ? 11.327  -58.222 -20.097 1.00 45.93  ? 136 LEU D N   1 
ATOM   5928 C CA  . LEU D 4 136 ? 11.179  -58.038 -18.658 1.00 49.04  ? 136 LEU D CA  1 
ATOM   5929 C C   . LEU D 4 136 ? 9.724   -57.679 -18.397 1.00 54.81  ? 136 LEU D C   1 
ATOM   5930 O O   . LEU D 4 136 ? 9.258   -56.625 -18.840 1.00 69.07  ? 136 LEU D O   1 
ATOM   5931 C CB  . LEU D 4 136 ? 12.107  -56.939 -18.134 1.00 44.84  ? 136 LEU D CB  1 
ATOM   5932 C CG  . LEU D 4 136 ? 13.631  -57.087 -18.183 1.00 36.50  ? 136 LEU D CG  1 
ATOM   5933 C CD1 . LEU D 4 136 ? 14.178  -57.017 -19.604 1.00 44.66  ? 136 LEU D CD1 1 
ATOM   5934 C CD2 . LEU D 4 136 ? 14.270  -56.013 -17.320 1.00 31.90  ? 136 LEU D CD2 1 
ATOM   5935 N N   . ASN D 4 137 ? 9.009   -58.546 -17.687 1.00 53.16  ? 137 ASN D N   1 
ATOM   5936 C CA  . ASN D 4 137 ? 7.561   -58.439 -17.587 1.00 60.28  ? 137 ASN D CA  1 
ATOM   5937 C C   . ASN D 4 137 ? 7.121   -58.382 -16.131 1.00 64.27  ? 137 ASN D C   1 
ATOM   5938 O O   . ASN D 4 137 ? 7.636   -59.124 -15.289 1.00 67.99  ? 137 ASN D O   1 
ATOM   5939 C CB  . ASN D 4 137 ? 6.881   -59.619 -18.292 1.00 72.32  ? 137 ASN D CB  1 
ATOM   5940 C CG  . ASN D 4 137 ? 5.422   -59.357 -18.592 1.00 75.01  ? 137 ASN D CG  1 
ATOM   5941 O OD1 . ASN D 4 137 ? 4.556   -59.549 -17.741 1.00 75.12  ? 137 ASN D OD1 1 
ATOM   5942 N ND2 . ASN D 4 137 ? 5.139   -58.920 -19.813 1.00 69.54  ? 137 ASN D ND2 1 
ATOM   5943 N N   . ASN D 4 138 ? 6.165   -57.494 -15.849 1.00 64.06  ? 138 ASN D N   1 
ATOM   5944 C CA  . ASN D 4 138 ? 5.510   -57.391 -14.542 1.00 62.15  ? 138 ASN D CA  1 
ATOM   5945 C C   . ASN D 4 138 ? 6.523   -57.155 -13.420 1.00 58.14  ? 138 ASN D C   1 
ATOM   5946 O O   . ASN D 4 138 ? 6.696   -57.977 -12.517 1.00 75.57  ? 138 ASN D O   1 
ATOM   5947 C CB  . ASN D 4 138 ? 4.659   -58.635 -14.258 1.00 68.30  ? 138 ASN D CB  1 
ATOM   5948 C CG  . ASN D 4 138 ? 3.428   -58.715 -15.139 1.00 71.81  ? 138 ASN D CG  1 
ATOM   5949 O OD1 . ASN D 4 138 ? 2.917   -57.696 -15.606 1.00 70.08  ? 138 ASN D OD1 1 
ATOM   5950 N ND2 . ASN D 4 138 ? 2.946   -59.931 -15.374 1.00 67.64  ? 138 ASN D ND2 1 
ATOM   5951 N N   . PHE D 4 139 ? 7.194   -56.007 -13.484 1.00 53.92  ? 139 PHE D N   1 
ATOM   5952 C CA  . PHE D 4 139 ? 8.178   -55.649 -12.474 1.00 64.05  ? 139 PHE D CA  1 
ATOM   5953 C C   . PHE D 4 139 ? 7.956   -54.223 -11.992 1.00 74.63  ? 139 PHE D C   1 
ATOM   5954 O O   . PHE D 4 139 ? 7.546   -53.343 -12.754 1.00 74.52  ? 139 PHE D O   1 
ATOM   5955 C CB  . PHE D 4 139 ? 9.616   -55.800 -12.997 1.00 67.56  ? 139 PHE D CB  1 
ATOM   5956 C CG  . PHE D 4 139 ? 9.957   -54.880 -14.137 1.00 62.15  ? 139 PHE D CG  1 
ATOM   5957 C CD1 . PHE D 4 139 ? 9.715   -55.259 -15.447 1.00 55.99  ? 139 PHE D CD1 1 
ATOM   5958 C CD2 . PHE D 4 139 ? 10.540  -53.645 -13.899 1.00 53.28  ? 139 PHE D CD2 1 
ATOM   5959 C CE1 . PHE D 4 139 ? 10.036  -54.419 -16.497 1.00 48.89  ? 139 PHE D CE1 1 
ATOM   5960 C CE2 . PHE D 4 139 ? 10.860  -52.800 -14.944 1.00 49.41  ? 139 PHE D CE2 1 
ATOM   5961 C CZ  . PHE D 4 139 ? 10.608  -53.187 -16.245 1.00 47.77  ? 139 PHE D CZ  1 
ATOM   5962 N N   . TYR D 4 140 ? 8.228   -54.014 -10.704 1.00 76.15  ? 140 TYR D N   1 
ATOM   5963 C CA  . TYR D 4 140 ? 8.254   -52.704 -10.084 1.00 65.81  ? 140 TYR D CA  1 
ATOM   5964 C C   . TYR D 4 140 ? 9.438   -52.698 -9.125  1.00 66.46  ? 140 TYR D C   1 
ATOM   5965 O O   . TYR D 4 140 ? 9.672   -53.698 -8.431  1.00 64.75  ? 140 TYR D O   1 
ATOM   5966 C CB  . TYR D 4 140 ? 6.956   -52.390 -9.326  1.00 68.70  ? 140 TYR D CB  1 
ATOM   5967 C CG  . TYR D 4 140 ? 6.749   -50.915 -9.080  1.00 78.00  ? 140 TYR D CG  1 
ATOM   5968 C CD1 . TYR D 4 140 ? 6.176   -50.108 -10.053 1.00 80.60  ? 140 TYR D CD1 1 
ATOM   5969 C CD2 . TYR D 4 140 ? 7.135   -50.327 -7.883  1.00 78.25  ? 140 TYR D CD2 1 
ATOM   5970 C CE1 . TYR D 4 140 ? 5.989   -48.758 -9.840  1.00 82.90  ? 140 TYR D CE1 1 
ATOM   5971 C CE2 . TYR D 4 140 ? 6.953   -48.976 -7.661  1.00 85.01  ? 140 TYR D CE2 1 
ATOM   5972 C CZ  . TYR D 4 140 ? 6.379   -48.197 -8.644  1.00 95.26  ? 140 TYR D CZ  1 
ATOM   5973 O OH  . TYR D 4 140 ? 6.193   -46.850 -8.435  1.00 104.24 ? 140 TYR D OH  1 
ATOM   5974 N N   . PRO D 4 141 ? 10.205  -51.599 -9.061  1.00 71.53  ? 141 PRO D N   1 
ATOM   5975 C CA  . PRO D 4 141 ? 10.052  -50.325 -9.780  1.00 64.42  ? 141 PRO D CA  1 
ATOM   5976 C C   . PRO D 4 141 ? 10.525  -50.371 -11.230 1.00 63.72  ? 141 PRO D C   1 
ATOM   5977 O O   . PRO D 4 141 ? 11.027  -51.384 -11.710 1.00 67.80  ? 141 PRO D O   1 
ATOM   5978 C CB  . PRO D 4 141 ? 10.906  -49.367 -8.942  1.00 51.87  ? 141 PRO D CB  1 
ATOM   5979 C CG  . PRO D 4 141 ? 12.016  -50.235 -8.440  1.00 64.50  ? 141 PRO D CG  1 
ATOM   5980 C CD  . PRO D 4 141 ? 11.370  -51.571 -8.157  1.00 75.93  ? 141 PRO D CD  1 
ATOM   5981 N N   . ARG D 4 142 ? 10.358  -49.251 -11.937 1.00 66.54  ? 142 ARG D N   1 
ATOM   5982 C CA  . ARG D 4 142 ? 10.709  -49.182 -13.352 1.00 76.59  ? 142 ARG D CA  1 
ATOM   5983 C C   . ARG D 4 142 ? 12.208  -49.354 -13.573 1.00 72.36  ? 142 ARG D C   1 
ATOM   5984 O O   . ARG D 4 142 ? 12.625  -49.971 -14.561 1.00 78.13  ? 142 ARG D O   1 
ATOM   5985 C CB  . ARG D 4 142 ? 10.228  -47.852 -13.934 1.00 72.80  ? 142 ARG D CB  1 
ATOM   5986 C CG  . ARG D 4 142 ? 10.695  -47.564 -15.351 1.00 68.83  ? 142 ARG D CG  1 
ATOM   5987 C CD  . ARG D 4 142 ? 10.044  -46.300 -15.883 1.00 69.84  ? 142 ARG D CD  1 
ATOM   5988 N NE  . ARG D 4 142 ? 10.537  -45.931 -17.204 1.00 75.83  ? 142 ARG D NE  1 
ATOM   5989 C CZ  . ARG D 4 142 ? 9.997   -44.988 -17.965 1.00 95.68  ? 142 ARG D CZ  1 
ATOM   5990 N NH1 . ARG D 4 142 ? 8.924   -44.318 -17.578 1.00 109.44 ? 142 ARG D NH1 1 
ATOM   5991 N NH2 . ARG D 4 142 ? 10.546  -44.713 -19.144 1.00 102.56 ? 142 ARG D NH2 1 
ATOM   5992 N N   . GLU D 4 143 ? 13.028  -48.819 -12.670 1.00 70.30  ? 143 GLU D N   1 
ATOM   5993 C CA  . GLU D 4 143 ? 14.476  -48.818 -12.855 1.00 67.00  ? 143 GLU D CA  1 
ATOM   5994 C C   . GLU D 4 143 ? 15.006  -50.239 -12.997 1.00 58.70  ? 143 GLU D C   1 
ATOM   5995 O O   . GLU D 4 143 ? 14.867  -51.060 -12.084 1.00 71.55  ? 143 GLU D O   1 
ATOM   5996 C CB  . GLU D 4 143 ? 15.155  -48.116 -11.678 1.00 73.09  ? 143 GLU D CB  1 
ATOM   5997 C CG  . GLU D 4 143 ? 14.804  -46.641 -11.517 1.00 90.78  ? 143 GLU D CG  1 
ATOM   5998 C CD  . GLU D 4 143 ? 13.424  -46.421 -10.924 1.00 91.44  ? 143 GLU D CD  1 
ATOM   5999 O OE1 . GLU D 4 143 ? 12.432  -46.469 -11.684 1.00 92.34  ? 143 GLU D OE1 1 
ATOM   6000 O OE2 . GLU D 4 143 ? 13.330  -46.212 -9.696  1.00 82.58  ? 143 GLU D OE2 1 
ATOM   6001 N N   . ALA D 4 144 ? 15.619  -50.525 -14.144 1.00 55.98  ? 144 ALA D N   1 
ATOM   6002 C CA  . ALA D 4 144 ? 16.181  -51.840 -14.411 1.00 45.99  ? 144 ALA D CA  1 
ATOM   6003 C C   . ALA D 4 144 ? 17.372  -51.690 -15.346 1.00 43.14  ? 144 ALA D C   1 
ATOM   6004 O O   . ALA D 4 144 ? 17.495  -50.703 -16.076 1.00 47.25  ? 144 ALA D O   1 
ATOM   6005 C CB  . ALA D 4 144 ? 15.141  -52.792 -15.014 1.00 31.97  ? 144 ALA D CB  1 
ATOM   6006 N N   . LYS D 4 145 ? 18.250  -52.689 -15.314 1.00 50.44  ? 145 LYS D N   1 
ATOM   6007 C CA  . LYS D 4 145 ? 19.477  -52.692 -16.100 1.00 38.16  ? 145 LYS D CA  1 
ATOM   6008 C C   . LYS D 4 145 ? 19.533  -53.966 -16.927 1.00 42.21  ? 145 LYS D C   1 
ATOM   6009 O O   . LYS D 4 145 ? 19.417  -55.068 -16.382 1.00 41.32  ? 145 LYS D O   1 
ATOM   6010 C CB  . LYS D 4 145 ? 20.704  -52.593 -15.189 1.00 45.79  ? 145 LYS D CB  1 
ATOM   6011 C CG  . LYS D 4 145 ? 22.035  -52.499 -15.911 1.00 39.79  ? 145 LYS D CG  1 
ATOM   6012 C CD  . LYS D 4 145 ? 23.171  -52.799 -14.947 1.00 43.95  ? 145 LYS D CD  1 
ATOM   6013 C CE  . LYS D 4 145 ? 24.528  -52.496 -15.554 1.00 45.85  ? 145 LYS D CE  1 
ATOM   6014 N NZ  . LYS D 4 145 ? 25.630  -52.886 -14.629 1.00 54.34  ? 145 LYS D NZ  1 
ATOM   6015 N N   . VAL D 4 146 ? 19.713  -53.817 -18.237 1.00 45.23  ? 146 VAL D N   1 
ATOM   6016 C CA  . VAL D 4 146 ? 19.785  -54.943 -19.161 1.00 47.14  ? 146 VAL D CA  1 
ATOM   6017 C C   . VAL D 4 146 ? 21.118  -54.889 -19.891 1.00 36.50  ? 146 VAL D C   1 
ATOM   6018 O O   . VAL D 4 146 ? 21.462  -53.865 -20.493 1.00 45.57  ? 146 VAL D O   1 
ATOM   6019 C CB  . VAL D 4 146 ? 18.615  -54.937 -20.162 1.00 38.10  ? 146 VAL D CB  1 
ATOM   6020 C CG1 . VAL D 4 146 ? 18.805  -56.029 -21.202 1.00 40.41  ? 146 VAL D CG1 1 
ATOM   6021 C CG2 . VAL D 4 146 ? 17.296  -55.118 -19.432 1.00 40.12  ? 146 VAL D CG2 1 
ATOM   6022 N N   . GLN D 4 147 ? 21.862  -55.991 -19.840 1.00 36.08  ? 147 GLN D N   1 
ATOM   6023 C CA  . GLN D 4 147 ? 23.133  -56.127 -20.535 1.00 39.66  ? 147 GLN D CA  1 
ATOM   6024 C C   . GLN D 4 147 ? 23.063  -57.306 -21.493 1.00 33.53  ? 147 GLN D C   1 
ATOM   6025 O O   . GLN D 4 147 ? 22.504  -58.356 -21.161 1.00 37.36  ? 147 GLN D O   1 
ATOM   6026 C CB  . GLN D 4 147 ? 24.291  -56.324 -19.550 1.00 42.08  ? 147 GLN D CB  1 
ATOM   6027 C CG  . GLN D 4 147 ? 24.837  -55.033 -18.961 1.00 52.43  ? 147 GLN D CG  1 
ATOM   6028 C CD  . GLN D 4 147 ? 25.804  -55.279 -17.818 1.00 60.44  ? 147 GLN D CD  1 
ATOM   6029 O OE1 . GLN D 4 147 ? 25.639  -56.223 -17.043 1.00 67.15  ? 147 GLN D OE1 1 
ATOM   6030 N NE2 . GLN D 4 147 ? 26.821  -54.432 -17.708 1.00 67.77  ? 147 GLN D NE2 1 
ATOM   6031 N N   . TRP D 4 148 ? 23.626  -57.123 -22.684 1.00 32.02  ? 148 TRP D N   1 
ATOM   6032 C CA  . TRP D 4 148 ? 23.701  -58.177 -23.687 1.00 29.40  ? 148 TRP D CA  1 
ATOM   6033 C C   . TRP D 4 148 ? 25.104  -58.769 -23.682 1.00 43.67  ? 148 TRP D C   1 
ATOM   6034 O O   . TRP D 4 148 ? 26.086  -58.052 -23.904 1.00 57.65  ? 148 TRP D O   1 
ATOM   6035 C CB  . TRP D 4 148 ? 23.350  -57.643 -25.075 1.00 38.76  ? 148 TRP D CB  1 
ATOM   6036 C CG  . TRP D 4 148 ? 21.880  -57.498 -25.301 1.00 39.12  ? 148 TRP D CG  1 
ATOM   6037 C CD1 . TRP D 4 148 ? 21.170  -56.335 -25.362 1.00 40.86  ? 148 TRP D CD1 1 
ATOM   6038 C CD2 . TRP D 4 148 ? 20.935  -58.557 -25.486 1.00 45.24  ? 148 TRP D CD2 1 
ATOM   6039 N NE1 . TRP D 4 148 ? 19.840  -56.604 -25.580 1.00 50.60  ? 148 TRP D NE1 1 
ATOM   6040 C CE2 . TRP D 4 148 ? 19.670  -57.961 -25.659 1.00 51.92  ? 148 TRP D CE2 1 
ATOM   6041 C CE3 . TRP D 4 148 ? 21.035  -59.951 -25.524 1.00 44.53  ? 148 TRP D CE3 1 
ATOM   6042 C CZ2 . TRP D 4 148 ? 18.515  -58.711 -25.866 1.00 49.42  ? 148 TRP D CZ2 1 
ATOM   6043 C CZ3 . TRP D 4 148 ? 19.887  -60.693 -25.730 1.00 49.00  ? 148 TRP D CZ3 1 
ATOM   6044 C CH2 . TRP D 4 148 ? 18.644  -60.072 -25.898 1.00 49.37  ? 148 TRP D CH2 1 
ATOM   6045 N N   . LYS D 4 149 ? 25.191  -60.071 -23.427 1.00 43.08  ? 149 LYS D N   1 
ATOM   6046 C CA  . LYS D 4 149 ? 26.452  -60.801 -23.441 1.00 39.26  ? 149 LYS D CA  1 
ATOM   6047 C C   . LYS D 4 149 ? 26.381  -61.855 -24.534 1.00 35.10  ? 149 LYS D C   1 
ATOM   6048 O O   . LYS D 4 149 ? 25.485  -62.706 -24.523 1.00 41.62  ? 149 LYS D O   1 
ATOM   6049 C CB  . LYS D 4 149 ? 26.729  -61.445 -22.082 1.00 37.55  ? 149 LYS D CB  1 
ATOM   6050 C CG  . LYS D 4 149 ? 26.799  -60.458 -20.930 1.00 43.09  ? 149 LYS D CG  1 
ATOM   6051 C CD  . LYS D 4 149 ? 28.145  -60.542 -20.237 1.00 47.16  ? 149 LYS D CD  1 
ATOM   6052 C CE  . LYS D 4 149 ? 27.986  -60.593 -18.730 1.00 38.89  ? 149 LYS D CE  1 
ATOM   6053 N NZ  . LYS D 4 149 ? 29.171  -61.220 -18.081 1.00 63.85  ? 149 LYS D NZ  1 
ATOM   6054 N N   . VAL D 4 150 ? 27.317  -61.792 -25.476 1.00 36.07  ? 150 VAL D N   1 
ATOM   6055 C CA  . VAL D 4 150 ? 27.398  -62.742 -26.578 1.00 40.91  ? 150 VAL D CA  1 
ATOM   6056 C C   . VAL D 4 150 ? 28.715  -63.492 -26.430 1.00 40.74  ? 150 VAL D C   1 
ATOM   6057 O O   . VAL D 4 150 ? 29.794  -62.895 -26.551 1.00 36.42  ? 150 VAL D O   1 
ATOM   6058 C CB  . VAL D 4 150 ? 27.300  -62.046 -27.944 1.00 44.05  ? 150 VAL D CB  1 
ATOM   6059 C CG1 . VAL D 4 150 ? 27.821  -62.948 -29.031 1.00 41.54  ? 150 VAL D CG1 1 
ATOM   6060 C CG2 . VAL D 4 150 ? 25.859  -61.649 -28.230 1.00 38.77  ? 150 VAL D CG2 1 
ATOM   6061 N N   . ASP D 4 151 ? 28.627  -64.798 -26.179 1.00 35.38  ? 151 ASP D N   1 
ATOM   6062 C CA  . ASP D 4 151 ? 29.797  -65.626 -25.878 1.00 36.86  ? 151 ASP D CA  1 
ATOM   6063 C C   . ASP D 4 151 ? 30.608  -65.026 -24.731 1.00 41.82  ? 151 ASP D C   1 
ATOM   6064 O O   . ASP D 4 151 ? 31.838  -64.960 -24.779 1.00 48.90  ? 151 ASP D O   1 
ATOM   6065 C CB  . ASP D 4 151 ? 30.665  -65.827 -27.122 1.00 43.39  ? 151 ASP D CB  1 
ATOM   6066 C CG  . ASP D 4 151 ? 29.939  -66.570 -28.227 1.00 44.78  ? 151 ASP D CG  1 
ATOM   6067 O OD1 . ASP D 4 151 ? 29.097  -67.438 -27.910 1.00 43.78  ? 151 ASP D OD1 1 
ATOM   6068 O OD2 . ASP D 4 151 ? 30.209  -66.289 -29.414 1.00 41.78  ? 151 ASP D OD2 1 
ATOM   6069 N N   . ASN D 4 152 ? 29.899  -64.573 -23.693 1.00 36.73  ? 152 ASN D N   1 
ATOM   6070 C CA  . ASN D 4 152 ? 30.480  -63.937 -22.510 1.00 40.62  ? 152 ASN D CA  1 
ATOM   6071 C C   . ASN D 4 152 ? 31.205  -62.635 -22.839 1.00 46.48  ? 152 ASN D C   1 
ATOM   6072 O O   . ASN D 4 152 ? 32.082  -62.203 -22.083 1.00 58.86  ? 152 ASN D O   1 
ATOM   6073 C CB  . ASN D 4 152 ? 31.423  -64.890 -21.763 1.00 30.59  ? 152 ASN D CB  1 
ATOM   6074 C CG  . ASN D 4 152 ? 30.718  -65.674 -20.675 1.00 49.43  ? 152 ASN D CG  1 
ATOM   6075 O OD1 . ASN D 4 152 ? 30.914  -65.419 -19.487 1.00 56.63  ? 152 ASN D OD1 1 
ATOM   6076 N ND2 . ASN D 4 152 ? 29.888  -66.630 -21.076 1.00 58.71  ? 152 ASN D ND2 1 
ATOM   6077 N N   . ALA D 4 153 ? 30.858  -61.996 -23.952 1.00 35.23  ? 153 ALA D N   1 
ATOM   6078 C CA  . ALA D 4 153 ? 31.418  -60.704 -24.328 1.00 35.46  ? 153 ALA D CA  1 
ATOM   6079 C C   . ALA D 4 153 ? 30.309  -59.662 -24.281 1.00 43.40  ? 153 ALA D C   1 
ATOM   6080 O O   . ALA D 4 153 ? 29.297  -59.798 -24.977 1.00 44.78  ? 153 ALA D O   1 
ATOM   6081 C CB  . ALA D 4 153 ? 32.051  -60.760 -25.718 1.00 28.42  ? 153 ALA D CB  1 
ATOM   6082 N N   . LEU D 4 154 ? 30.502  -58.631 -23.460 1.00 34.34  ? 154 LEU D N   1 
ATOM   6083 C CA  . LEU D 4 154 ? 29.504  -57.577 -23.336 1.00 37.07  ? 154 LEU D CA  1 
ATOM   6084 C C   . LEU D 4 154 ? 29.302  -56.889 -24.680 1.00 41.90  ? 154 LEU D C   1 
ATOM   6085 O O   . LEU D 4 154 ? 30.265  -56.472 -25.330 1.00 44.19  ? 154 LEU D O   1 
ATOM   6086 C CB  . LEU D 4 154 ? 29.937  -56.564 -22.277 1.00 37.95  ? 154 LEU D CB  1 
ATOM   6087 C CG  . LEU D 4 154 ? 28.859  -55.611 -21.756 1.00 41.74  ? 154 LEU D CG  1 
ATOM   6088 C CD1 . LEU D 4 154 ? 27.857  -56.359 -20.889 1.00 48.05  ? 154 LEU D CD1 1 
ATOM   6089 C CD2 . LEU D 4 154 ? 29.483  -54.454 -20.990 1.00 34.80  ? 154 LEU D CD2 1 
ATOM   6090 N N   . GLN D 4 155 ? 28.045  -56.772 -25.094 1.00 38.28  ? 155 GLN D N   1 
ATOM   6091 C CA  . GLN D 4 155 ? 27.691  -56.230 -26.397 1.00 46.79  ? 155 GLN D CA  1 
ATOM   6092 C C   . GLN D 4 155 ? 27.066  -54.854 -26.218 1.00 45.47  ? 155 GLN D C   1 
ATOM   6093 O O   . GLN D 4 155 ? 26.106  -54.699 -25.455 1.00 51.35  ? 155 GLN D O   1 
ATOM   6094 C CB  . GLN D 4 155 ? 26.726  -57.164 -27.132 1.00 42.57  ? 155 GLN D CB  1 
ATOM   6095 C CG  . GLN D 4 155 ? 26.729  -57.002 -28.643 1.00 36.42  ? 155 GLN D CG  1 
ATOM   6096 C CD  . GLN D 4 155 ? 27.990  -57.546 -29.285 1.00 48.69  ? 155 GLN D CD  1 
ATOM   6097 O OE1 . GLN D 4 155 ? 28.732  -58.315 -28.672 1.00 55.53  ? 155 GLN D OE1 1 
ATOM   6098 N NE2 . GLN D 4 155 ? 28.240  -57.150 -30.528 1.00 37.35  ? 155 GLN D NE2 1 
ATOM   6099 N N   . SER D 4 156 ? 27.610  -53.863 -26.920 1.00 35.88  ? 156 SER D N   1 
ATOM   6100 C CA  . SER D 4 156 ? 27.145  -52.488 -26.820 1.00 39.29  ? 156 SER D CA  1 
ATOM   6101 C C   . SER D 4 156 ? 26.987  -51.889 -28.210 1.00 38.44  ? 156 SER D C   1 
ATOM   6102 O O   . SER D 4 156 ? 27.720  -52.231 -29.141 1.00 49.72  ? 156 SER D O   1 
ATOM   6103 C CB  . SER D 4 156 ? 28.112  -51.627 -25.992 1.00 37.52  ? 156 SER D CB  1 
ATOM   6104 O OG  . SER D 4 156 ? 28.243  -52.129 -24.674 1.00 48.07  ? 156 SER D OG  1 
ATOM   6105 N N   . GLY D 4 157 ? 26.013  -50.987 -28.338 1.00 35.73  ? 157 GLY D N   1 
ATOM   6106 C CA  . GLY D 4 157 ? 25.817  -50.224 -29.552 1.00 48.70  ? 157 GLY D CA  1 
ATOM   6107 C C   . GLY D 4 157 ? 24.818  -50.786 -30.538 1.00 43.90  ? 157 GLY D C   1 
ATOM   6108 O O   . GLY D 4 157 ? 24.600  -50.166 -31.586 1.00 38.26  ? 157 GLY D O   1 
ATOM   6109 N N   . ASN D 4 158 ? 24.210  -51.936 -30.251 1.00 47.93  ? 158 ASN D N   1 
ATOM   6110 C CA  . ASN D 4 158 ? 23.232  -52.533 -31.155 1.00 53.35  ? 158 ASN D CA  1 
ATOM   6111 C C   . ASN D 4 158 ? 22.037  -53.068 -30.379 1.00 51.80  ? 158 ASN D C   1 
ATOM   6112 O O   . ASN D 4 158 ? 21.477  -54.118 -30.711 1.00 49.63  ? 158 ASN D O   1 
ATOM   6113 C CB  . ASN D 4 158 ? 23.864  -53.637 -32.003 1.00 51.75  ? 158 ASN D CB  1 
ATOM   6114 C CG  . ASN D 4 158 ? 24.471  -54.744 -31.163 1.00 54.17  ? 158 ASN D CG  1 
ATOM   6115 O OD1 . ASN D 4 158 ? 25.040  -54.494 -30.101 1.00 48.28  ? 158 ASN D OD1 1 
ATOM   6116 N ND2 . ASN D 4 158 ? 24.353  -55.979 -31.640 1.00 61.23  ? 158 ASN D ND2 1 
ATOM   6117 N N   . SER D 4 159 ? 21.629  -52.353 -29.333 1.00 48.21  ? 159 SER D N   1 
ATOM   6118 C CA  . SER D 4 159 ? 20.469  -52.741 -28.545 1.00 45.25  ? 159 SER D CA  1 
ATOM   6119 C C   . SER D 4 159 ? 19.607  -51.518 -28.276 1.00 41.29  ? 159 SER D C   1 
ATOM   6120 O O   . SER D 4 159 ? 20.126  -50.429 -28.016 1.00 49.03  ? 159 SER D O   1 
ATOM   6121 C CB  . SER D 4 159 ? 20.882  -53.394 -27.220 1.00 32.20  ? 159 SER D CB  1 
ATOM   6122 O OG  . SER D 4 159 ? 21.523  -52.461 -26.370 1.00 50.47  ? 159 SER D OG  1 
ATOM   6123 N N   . GLN D 4 160 ? 18.291  -51.705 -28.342 1.00 41.84  ? 160 GLN D N   1 
ATOM   6124 C CA  . GLN D 4 160 ? 17.332  -50.654 -28.040 1.00 39.99  ? 160 GLN D CA  1 
ATOM   6125 C C   . GLN D 4 160 ? 16.312  -51.175 -27.039 1.00 39.32  ? 160 GLN D C   1 
ATOM   6126 O O   . GLN D 4 160 ? 16.002  -52.369 -27.006 1.00 41.59  ? 160 GLN D O   1 
ATOM   6127 C CB  . GLN D 4 160 ? 16.624  -50.150 -29.304 1.00 38.88  ? 160 GLN D CB  1 
ATOM   6128 C CG  . GLN D 4 160 ? 17.510  -49.311 -30.212 1.00 38.78  ? 160 GLN D CG  1 
ATOM   6129 C CD  . GLN D 4 160 ? 16.769  -48.784 -31.425 1.00 50.13  ? 160 GLN D CD  1 
ATOM   6130 O OE1 . GLN D 4 160 ? 15.779  -49.368 -31.865 1.00 59.81  ? 160 GLN D OE1 1 
ATOM   6131 N NE2 . GLN D 4 160 ? 17.244  -47.669 -31.969 1.00 50.77  ? 160 GLN D NE2 1 
ATOM   6132 N N   . GLU D 4 161 ? 15.797  -50.264 -26.219 1.00 39.36  ? 161 GLU D N   1 
ATOM   6133 C CA  . GLU D 4 161 ? 14.902  -50.612 -25.127 1.00 40.26  ? 161 GLU D CA  1 
ATOM   6134 C C   . GLU D 4 161 ? 13.576  -49.879 -25.274 1.00 36.18  ? 161 GLU D C   1 
ATOM   6135 O O   . GLU D 4 161 ? 13.505  -48.799 -25.867 1.00 32.49  ? 161 GLU D O   1 
ATOM   6136 C CB  . GLU D 4 161 ? 15.538  -50.281 -23.773 1.00 47.03  ? 161 GLU D CB  1 
ATOM   6137 C CG  . GLU D 4 161 ? 16.969  -50.772 -23.645 1.00 53.88  ? 161 GLU D CG  1 
ATOM   6138 C CD  . GLU D 4 161 ? 17.247  -51.441 -22.314 1.00 73.75  ? 161 GLU D CD  1 
ATOM   6139 O OE1 . GLU D 4 161 ? 16.971  -50.824 -21.263 1.00 55.98  ? 161 GLU D OE1 1 
ATOM   6140 O OE2 . GLU D 4 161 ? 17.736  -52.591 -22.324 1.00 83.60  ? 161 GLU D OE2 1 
ATOM   6141 N N   . SER D 4 162 ? 12.522  -50.486 -24.731 1.00 37.63  ? 162 SER D N   1 
ATOM   6142 C CA  . SER D 4 162 ? 11.189  -49.902 -24.762 1.00 46.35  ? 162 SER D CA  1 
ATOM   6143 C C   . SER D 4 162 ? 10.436  -50.338 -23.515 1.00 45.34  ? 162 SER D C   1 
ATOM   6144 O O   . SER D 4 162 ? 10.400  -51.530 -23.198 1.00 46.17  ? 162 SER D O   1 
ATOM   6145 C CB  . SER D 4 162 ? 10.425  -50.327 -26.021 1.00 55.01  ? 162 SER D CB  1 
ATOM   6146 O OG  . SER D 4 162 ? 9.151   -49.711 -26.072 1.00 44.32  ? 162 SER D OG  1 
ATOM   6147 N N   . VAL D 4 163 ? 9.833   -49.377 -22.822 1.00 46.14  ? 163 VAL D N   1 
ATOM   6148 C CA  . VAL D 4 163 ? 9.114   -49.625 -21.578 1.00 52.96  ? 163 VAL D CA  1 
ATOM   6149 C C   . VAL D 4 163 ? 7.666   -49.195 -21.757 1.00 49.12  ? 163 VAL D C   1 
ATOM   6150 O O   . VAL D 4 163 ? 7.394   -48.091 -22.242 1.00 56.99  ? 163 VAL D O   1 
ATOM   6151 C CB  . VAL D 4 163 ? 9.758   -48.884 -20.392 1.00 56.11  ? 163 VAL D CB  1 
ATOM   6152 C CG1 . VAL D 4 163 ? 10.932  -49.674 -19.844 1.00 56.80  ? 163 VAL D CG1 1 
ATOM   6153 C CG2 . VAL D 4 163 ? 10.205  -47.497 -20.819 1.00 56.61  ? 163 VAL D CG2 1 
ATOM   6154 N N   . THR D 4 164 ? 6.741   -50.070 -21.373 1.00 50.85  ? 164 THR D N   1 
ATOM   6155 C CA  . THR D 4 164 ? 5.335   -49.708 -21.347 1.00 53.50  ? 164 THR D CA  1 
ATOM   6156 C C   . THR D 4 164 ? 5.044   -48.808 -20.151 1.00 61.73  ? 164 THR D C   1 
ATOM   6157 O O   . THR D 4 164 ? 5.810   -48.742 -19.185 1.00 75.80  ? 164 THR D O   1 
ATOM   6158 C CB  . THR D 4 164 ? 4.447   -50.952 -21.281 1.00 46.14  ? 164 THR D CB  1 
ATOM   6159 O OG1 . THR D 4 164 ? 4.888   -51.803 -20.214 1.00 43.39  ? 164 THR D OG1 1 
ATOM   6160 C CG2 . THR D 4 164 ? 4.491   -51.715 -22.595 1.00 47.37  ? 164 THR D CG2 1 
ATOM   6161 N N   . GLU D 4 165 ? 3.917   -48.106 -20.227 1.00 64.05  ? 165 GLU D N   1 
ATOM   6162 C CA  . GLU D 4 165 ? 3.460   -47.331 -19.086 1.00 68.29  ? 165 GLU D CA  1 
ATOM   6163 C C   . GLU D 4 165 ? 2.974   -48.270 -17.983 1.00 69.00  ? 165 GLU D C   1 
ATOM   6164 O O   . GLU D 4 165 ? 2.908   -49.492 -18.150 1.00 64.21  ? 165 GLU D O   1 
ATOM   6165 C CB  . GLU D 4 165 ? 2.352   -46.365 -19.503 1.00 73.06  ? 165 GLU D CB  1 
ATOM   6166 C CG  . GLU D 4 165 ? 2.765   -45.359 -20.569 1.00 81.09  ? 165 GLU D CG  1 
ATOM   6167 C CD  . GLU D 4 165 ? 3.714   -44.295 -20.045 1.00 85.90  ? 165 GLU D CD  1 
ATOM   6168 O OE1 . GLU D 4 165 ? 3.807   -44.128 -18.810 1.00 92.79  ? 165 GLU D OE1 1 
ATOM   6169 O OE2 . GLU D 4 165 ? 4.368   -43.623 -20.871 1.00 74.11  ? 165 GLU D OE2 1 
ATOM   6170 N N   . GLN D 4 166 ? 2.633   -47.684 -16.838 1.00 66.66  ? 166 GLN D N   1 
ATOM   6171 C CA  . GLN D 4 166 ? 2.201   -48.486 -15.702 1.00 68.89  ? 166 GLN D CA  1 
ATOM   6172 C C   . GLN D 4 166 ? 0.920   -49.243 -16.033 1.00 68.71  ? 166 GLN D C   1 
ATOM   6173 O O   . GLN D 4 166 ? 0.044   -48.740 -16.743 1.00 60.71  ? 166 GLN D O   1 
ATOM   6174 C CB  . GLN D 4 166 ? 1.993   -47.601 -14.475 1.00 61.04  ? 166 GLN D CB  1 
ATOM   6175 C CG  . GLN D 4 166 ? 3.256   -46.905 -14.015 1.00 67.99  ? 166 GLN D CG  1 
ATOM   6176 C CD  . GLN D 4 166 ? 3.150   -46.386 -12.601 1.00 84.92  ? 166 GLN D CD  1 
ATOM   6177 O OE1 . GLN D 4 166 ? 2.749   -45.246 -12.376 1.00 81.39  ? 166 GLN D OE1 1 
ATOM   6178 N NE2 . GLN D 4 166 ? 3.506   -47.225 -11.634 1.00 84.71  ? 166 GLN D NE2 1 
ATOM   6179 N N   . ASP D 4 167 ? 0.822   -50.465 -15.517 1.00 78.91  ? 167 ASP D N   1 
ATOM   6180 C CA  . ASP D 4 167 ? -0.300  -51.333 -15.836 1.00 80.47  ? 167 ASP D CA  1 
ATOM   6181 C C   . ASP D 4 167 ? -1.606  -50.758 -15.300 1.00 92.50  ? 167 ASP D C   1 
ATOM   6182 O O   . ASP D 4 167 ? -1.634  -50.037 -14.298 1.00 93.67  ? 167 ASP D O   1 
ATOM   6183 C CB  . ASP D 4 167 ? -0.075  -52.733 -15.263 1.00 86.38  ? 167 ASP D CB  1 
ATOM   6184 C CG  . ASP D 4 167 ? -1.089  -53.743 -15.771 1.00 88.30  ? 167 ASP D CG  1 
ATOM   6185 O OD1 . ASP D 4 167 ? -1.888  -53.390 -16.667 1.00 85.27  ? 167 ASP D OD1 1 
ATOM   6186 O OD2 . ASP D 4 167 ? -1.082  -54.891 -15.275 1.00 93.39  ? 167 ASP D OD2 1 
ATOM   6187 N N   . SER D 4 168 ? -2.699  -51.095 -15.988 1.00 101.71 ? 168 SER D N   1 
ATOM   6188 C CA  . SER D 4 168 ? -4.010  -50.588 -15.603 1.00 98.77  ? 168 SER D CA  1 
ATOM   6189 C C   . SER D 4 168 ? -4.442  -51.110 -14.239 1.00 110.36 ? 168 SER D C   1 
ATOM   6190 O O   . SER D 4 168 ? -5.116  -50.395 -13.489 1.00 108.27 ? 168 SER D O   1 
ATOM   6191 C CB  . SER D 4 168 ? -5.044  -50.957 -16.666 1.00 96.43  ? 168 SER D CB  1 
ATOM   6192 O OG  . SER D 4 168 ? -5.070  -52.356 -16.885 1.00 100.76 ? 168 SER D OG  1 
ATOM   6193 N N   . LYS D 4 169 ? -4.082  -52.347 -13.904 1.00 101.59 ? 169 LYS D N   1 
ATOM   6194 C CA  . LYS D 4 169 ? -4.457  -52.931 -12.623 1.00 100.75 ? 169 LYS D CA  1 
ATOM   6195 C C   . LYS D 4 169 ? -3.257  -53.273 -11.755 1.00 104.97 ? 169 LYS D C   1 
ATOM   6196 O O   . LYS D 4 169 ? -3.197  -52.849 -10.594 1.00 105.70 ? 169 LYS D O   1 
ATOM   6197 C CB  . LYS D 4 169 ? -5.322  -54.182 -12.850 1.00 102.93 ? 169 LYS D CB  1 
ATOM   6198 C CG  . LYS D 4 169 ? -5.893  -54.780 -11.574 1.00 113.26 ? 169 LYS D CG  1 
ATOM   6199 C CD  . LYS D 4 169 ? -6.576  -53.719 -10.718 1.00 100.86 ? 169 LYS D CD  1 
ATOM   6200 C CE  . LYS D 4 169 ? -7.781  -53.110 -11.421 1.00 82.60  ? 169 LYS D CE  1 
ATOM   6201 N NZ  . LYS D 4 169 ? -8.258  -51.883 -10.725 1.00 64.44  ? 169 LYS D NZ  1 
ATOM   6202 N N   . ASP D 4 170 ? -2.290  -54.024 -12.285 1.00 103.47 ? 170 ASP D N   1 
ATOM   6203 C CA  . ASP D 4 170 ? -1.141  -54.435 -11.487 1.00 93.99  ? 170 ASP D CA  1 
ATOM   6204 C C   . ASP D 4 170 ? -0.185  -53.283 -11.209 1.00 85.65  ? 170 ASP D C   1 
ATOM   6205 O O   . ASP D 4 170 ? 0.646   -53.392 -10.301 1.00 76.46  ? 170 ASP D O   1 
ATOM   6206 C CB  . ASP D 4 170 ? -0.400  -55.573 -12.190 1.00 93.10  ? 170 ASP D CB  1 
ATOM   6207 C CG  . ASP D 4 170 ? -1.337  -56.656 -12.686 1.00 105.11 ? 170 ASP D CG  1 
ATOM   6208 O OD1 . ASP D 4 170 ? -2.366  -56.311 -13.307 1.00 104.86 ? 170 ASP D OD1 1 
ATOM   6209 O OD2 . ASP D 4 170 ? -1.039  -57.850 -12.464 1.00 93.14  ? 170 ASP D OD2 1 
ATOM   6210 N N   . SER D 4 171 ? -0.285  -52.189 -11.970 1.00 85.25  ? 171 SER D N   1 
ATOM   6211 C CA  . SER D 4 171 ? 0.593   -51.026 -11.827 1.00 86.81  ? 171 SER D CA  1 
ATOM   6212 C C   . SER D 4 171 ? 2.063   -51.394 -12.016 1.00 93.56  ? 171 SER D C   1 
ATOM   6213 O O   . SER D 4 171 ? 2.954   -50.736 -11.474 1.00 87.05  ? 171 SER D O   1 
ATOM   6214 C CB  . SER D 4 171 ? 0.388   -50.332 -10.478 1.00 90.97  ? 171 SER D CB  1 
ATOM   6215 O OG  . SER D 4 171 ? 1.398   -49.367 -10.254 1.00 93.76  ? 171 SER D OG  1 
ATOM   6216 N N   . THR D 4 172 ? 2.327   -52.441 -12.789 1.00 94.52  ? 172 THR D N   1 
ATOM   6217 C CA  . THR D 4 172 ? 3.681   -52.902 -13.052 1.00 79.87  ? 172 THR D CA  1 
ATOM   6218 C C   . THR D 4 172 ? 4.181   -52.349 -14.384 1.00 77.29  ? 172 THR D C   1 
ATOM   6219 O O   . THR D 4 172 ? 3.447   -51.710 -15.141 1.00 68.44  ? 172 THR D O   1 
ATOM   6220 C CB  . THR D 4 172 ? 3.740   -54.432 -13.054 1.00 79.48  ? 172 THR D CB  1 
ATOM   6221 O OG1 . THR D 4 172 ? 2.893   -54.944 -14.091 1.00 79.08  ? 172 THR D OG1 1 
ATOM   6222 C CG2 . THR D 4 172 ? 3.279   -54.984 -11.713 1.00 79.75  ? 172 THR D CG2 1 
ATOM   6223 N N   . TYR D 4 173 ? 5.455   -52.604 -14.659 1.00 71.97  ? 173 TYR D N   1 
ATOM   6224 C CA  . TYR D 4 173 ? 6.102   -52.185 -15.893 1.00 56.09  ? 173 TYR D CA  1 
ATOM   6225 C C   . TYR D 4 173 ? 6.471   -53.398 -16.736 1.00 66.20  ? 173 TYR D C   1 
ATOM   6226 O O   . TYR D 4 173 ? 6.388   -54.548 -16.295 1.00 65.68  ? 173 TYR D O   1 
ATOM   6227 C CB  . TYR D 4 173 ? 7.354   -51.351 -15.597 1.00 55.38  ? 173 TYR D CB  1 
ATOM   6228 C CG  . TYR D 4 173 ? 7.079   -49.911 -15.228 1.00 66.01  ? 173 TYR D CG  1 
ATOM   6229 C CD1 . TYR D 4 173 ? 6.855   -49.541 -13.909 1.00 71.03  ? 173 TYR D CD1 1 
ATOM   6230 C CD2 . TYR D 4 173 ? 7.057   -48.919 -16.200 1.00 65.66  ? 173 TYR D CD2 1 
ATOM   6231 C CE1 . TYR D 4 173 ? 6.610   -48.224 -13.569 1.00 73.65  ? 173 TYR D CE1 1 
ATOM   6232 C CE2 . TYR D 4 173 ? 6.812   -47.601 -15.870 1.00 70.47  ? 173 TYR D CE2 1 
ATOM   6233 C CZ  . TYR D 4 173 ? 6.592   -47.258 -14.553 1.00 75.91  ? 173 TYR D CZ  1 
ATOM   6234 O OH  . TYR D 4 173 ? 6.347   -45.945 -14.219 1.00 72.66  ? 173 TYR D OH  1 
ATOM   6235 N N   . SER D 4 174 ? 6.885   -53.122 -17.971 1.00 56.22  ? 174 SER D N   1 
ATOM   6236 C CA  . SER D 4 174 ? 7.389   -54.151 -18.868 1.00 46.23  ? 174 SER D CA  1 
ATOM   6237 C C   . SER D 4 174 ? 8.389   -53.517 -19.823 1.00 52.76  ? 174 SER D C   1 
ATOM   6238 O O   . SER D 4 174 ? 8.150   -52.428 -20.349 1.00 43.19  ? 174 SER D O   1 
ATOM   6239 C CB  . SER D 4 174 ? 6.256   -54.832 -19.643 1.00 46.79  ? 174 SER D CB  1 
ATOM   6240 O OG  . SER D 4 174 ? 5.478   -55.652 -18.787 1.00 61.08  ? 174 SER D OG  1 
ATOM   6241 N N   . LEU D 4 175 ? 9.508   -54.208 -20.040 1.00 55.28  ? 175 LEU D N   1 
ATOM   6242 C CA  . LEU D 4 175 ? 10.612  -53.697 -20.842 1.00 46.77  ? 175 LEU D CA  1 
ATOM   6243 C C   . LEU D 4 175 ? 11.034  -54.740 -21.866 1.00 47.08  ? 175 LEU D C   1 
ATOM   6244 O O   . LEU D 4 175 ? 11.054  -55.938 -21.573 1.00 57.52  ? 175 LEU D O   1 
ATOM   6245 C CB  . LEU D 4 175 ? 11.807  -53.318 -19.952 1.00 49.06  ? 175 LEU D CB  1 
ATOM   6246 C CG  . LEU D 4 175 ? 13.175  -53.079 -20.600 1.00 49.08  ? 175 LEU D CG  1 
ATOM   6247 C CD1 . LEU D 4 175 ? 13.133  -51.925 -21.586 1.00 48.59  ? 175 LEU D CD1 1 
ATOM   6248 C CD2 . LEU D 4 175 ? 14.232  -52.832 -19.534 1.00 47.78  ? 175 LEU D CD2 1 
ATOM   6249 N N   . SER D 4 176 ? 11.367  -54.277 -23.070 1.00 41.25  ? 176 SER D N   1 
ATOM   6250 C CA  . SER D 4 176 ? 11.869  -55.138 -24.133 1.00 53.63  ? 176 SER D CA  1 
ATOM   6251 C C   . SER D 4 176 ? 13.207  -54.604 -24.618 1.00 46.85  ? 176 SER D C   1 
ATOM   6252 O O   . SER D 4 176 ? 13.311  -53.432 -24.994 1.00 46.21  ? 176 SER D O   1 
ATOM   6253 C CB  . SER D 4 176 ? 10.882  -55.219 -25.303 1.00 49.73  ? 176 SER D CB  1 
ATOM   6254 O OG  . SER D 4 176 ? 10.871  -54.011 -26.045 1.00 37.82  ? 176 SER D OG  1 
ATOM   6255 N N   . SER D 4 177 ? 14.222  -55.461 -24.612 1.00 45.07  ? 177 SER D N   1 
ATOM   6256 C CA  . SER D 4 177 ? 15.538  -55.133 -25.144 1.00 51.38  ? 177 SER D CA  1 
ATOM   6257 C C   . SER D 4 177 ? 15.769  -55.977 -26.390 1.00 43.05  ? 177 SER D C   1 
ATOM   6258 O O   . SER D 4 177 ? 15.756  -57.211 -26.318 1.00 37.62  ? 177 SER D O   1 
ATOM   6259 C CB  . SER D 4 177 ? 16.631  -55.384 -24.104 1.00 49.44  ? 177 SER D CB  1 
ATOM   6260 O OG  . SER D 4 177 ? 17.882  -54.886 -24.546 1.00 49.40  ? 177 SER D OG  1 
ATOM   6261 N N   . THR D 4 178 ? 15.979  -55.316 -27.524 1.00 46.89  ? 178 THR D N   1 
ATOM   6262 C CA  . THR D 4 178 ? 16.122  -55.984 -28.810 1.00 50.32  ? 178 THR D CA  1 
ATOM   6263 C C   . THR D 4 178 ? 17.545  -55.811 -29.322 1.00 47.61  ? 178 THR D C   1 
ATOM   6264 O O   . THR D 4 178 ? 18.041  -54.683 -29.422 1.00 43.22  ? 178 THR D O   1 
ATOM   6265 C CB  . THR D 4 178 ? 15.126  -55.433 -29.832 1.00 45.45  ? 178 THR D CB  1 
ATOM   6266 O OG1 . THR D 4 178 ? 15.540  -54.124 -30.245 1.00 63.69  ? 178 THR D OG1 1 
ATOM   6267 C CG2 . THR D 4 178 ? 13.734  -55.347 -29.223 1.00 32.52  ? 178 THR D CG2 1 
ATOM   6268 N N   . LEU D 4 179 ? 18.190  -56.926 -29.650 1.00 46.48  ? 179 LEU D N   1 
ATOM   6269 C CA  . LEU D 4 179 ? 19.544  -56.931 -30.188 1.00 42.82  ? 179 LEU D CA  1 
ATOM   6270 C C   . LEU D 4 179 ? 19.470  -57.204 -31.685 1.00 37.58  ? 179 LEU D C   1 
ATOM   6271 O O   . LEU D 4 179 ? 18.990  -58.264 -32.101 1.00 46.47  ? 179 LEU D O   1 
ATOM   6272 C CB  . LEU D 4 179 ? 20.399  -57.988 -29.489 1.00 40.50  ? 179 LEU D CB  1 
ATOM   6273 C CG  . LEU D 4 179 ? 21.898  -57.990 -29.788 1.00 35.99  ? 179 LEU D CG  1 
ATOM   6274 C CD1 . LEU D 4 179 ? 22.586  -56.871 -29.027 1.00 45.84  ? 179 LEU D CD1 1 
ATOM   6275 C CD2 . LEU D 4 179 ? 22.513  -59.336 -29.446 1.00 32.00  ? 179 LEU D CD2 1 
ATOM   6276 N N   . THR D 4 180 ? 19.945  -56.257 -32.489 1.00 28.47  ? 180 THR D N   1 
ATOM   6277 C CA  . THR D 4 180 ? 19.863  -56.347 -33.941 1.00 41.01  ? 180 THR D CA  1 
ATOM   6278 C C   . THR D 4 180 ? 21.256  -56.514 -34.528 1.00 56.01  ? 180 THR D C   1 
ATOM   6279 O O   . THR D 4 180 ? 22.166  -55.736 -34.218 1.00 55.83  ? 180 THR D O   1 
ATOM   6280 C CB  . THR D 4 180 ? 19.188  -55.108 -34.535 1.00 46.38  ? 180 THR D CB  1 
ATOM   6281 O OG1 . THR D 4 180 ? 17.834  -55.033 -34.073 1.00 66.36  ? 180 THR D OG1 1 
ATOM   6282 C CG2 . THR D 4 180 ? 19.194  -55.175 -36.057 1.00 47.20  ? 180 THR D CG2 1 
ATOM   6283 N N   . LEU D 4 181 ? 21.414  -57.527 -35.377 1.00 53.81  ? 181 LEU D N   1 
ATOM   6284 C CA  . LEU D 4 181 ? 22.681  -57.797 -36.038 1.00 42.95  ? 181 LEU D CA  1 
ATOM   6285 C C   . LEU D 4 181 ? 22.398  -58.544 -37.332 1.00 43.08  ? 181 LEU D C   1 
ATOM   6286 O O   . LEU D 4 181 ? 21.332  -59.142 -37.506 1.00 48.59  ? 181 LEU D O   1 
ATOM   6287 C CB  . LEU D 4 181 ? 23.641  -58.594 -35.139 1.00 33.51  ? 181 LEU D CB  1 
ATOM   6288 C CG  . LEU D 4 181 ? 23.256  -59.984 -34.616 1.00 37.15  ? 181 LEU D CG  1 
ATOM   6289 C CD1 . LEU D 4 181 ? 24.495  -60.704 -34.112 1.00 39.23  ? 181 LEU D CD1 1 
ATOM   6290 C CD2 . LEU D 4 181 ? 22.213  -59.913 -33.508 1.00 41.05  ? 181 LEU D CD2 1 
ATOM   6291 N N   . SER D 4 182 ? 23.364  -58.494 -38.245 1.00 43.74  ? 182 SER D N   1 
ATOM   6292 C CA  . SER D 4 182 ? 23.202  -59.140 -39.539 1.00 46.41  ? 182 SER D CA  1 
ATOM   6293 C C   . SER D 4 182 ? 23.159  -60.656 -39.383 1.00 59.27  ? 182 SER D C   1 
ATOM   6294 O O   . SER D 4 182 ? 23.684  -61.220 -38.419 1.00 68.77  ? 182 SER D O   1 
ATOM   6295 C CB  . SER D 4 182 ? 24.339  -58.744 -40.481 1.00 42.53  ? 182 SER D CB  1 
ATOM   6296 O OG  . SER D 4 182 ? 25.589  -59.198 -39.993 1.00 51.90  ? 182 SER D OG  1 
ATOM   6297 N N   . LYS D 4 183 ? 22.509  -61.315 -40.347 1.00 59.99  ? 183 LYS D N   1 
ATOM   6298 C CA  . LYS D 4 183 ? 22.450  -62.773 -40.331 1.00 64.68  ? 183 LYS D CA  1 
ATOM   6299 C C   . LYS D 4 183 ? 23.846  -63.378 -40.374 1.00 64.38  ? 183 LYS D C   1 
ATOM   6300 O O   . LYS D 4 183 ? 24.110  -64.397 -39.724 1.00 53.45  ? 183 LYS D O   1 
ATOM   6301 C CB  . LYS D 4 183 ? 21.614  -63.282 -41.506 1.00 57.55  ? 183 LYS D CB  1 
ATOM   6302 C CG  . LYS D 4 183 ? 21.404  -64.788 -41.506 1.00 64.10  ? 183 LYS D CG  1 
ATOM   6303 C CD  . LYS D 4 183 ? 21.179  -65.311 -42.915 1.00 73.40  ? 183 LYS D CD  1 
ATOM   6304 C CE  . LYS D 4 183 ? 20.750  -66.770 -42.902 1.00 61.06  ? 183 LYS D CE  1 
ATOM   6305 N NZ  . LYS D 4 183 ? 20.591  -67.310 -44.281 1.00 63.94  ? 183 LYS D NZ  1 
ATOM   6306 N N   . ALA D 4 184 ? 24.753  -62.765 -41.139 1.00 52.35  ? 184 ALA D N   1 
ATOM   6307 C CA  . ALA D 4 184 ? 26.133  -63.233 -41.164 1.00 52.18  ? 184 ALA D CA  1 
ATOM   6308 C C   . ALA D 4 184 ? 26.761  -63.143 -39.779 1.00 67.41  ? 184 ALA D C   1 
ATOM   6309 O O   . ALA D 4 184 ? 27.320  -64.123 -39.275 1.00 78.98  ? 184 ALA D O   1 
ATOM   6310 C CB  . ALA D 4 184 ? 26.939  -62.425 -42.180 1.00 45.04  ? 184 ALA D CB  1 
ATOM   6311 N N   . ASP D 4 185 ? 26.644  -61.978 -39.134 1.00 52.73  ? 185 ASP D N   1 
ATOM   6312 C CA  . ASP D 4 185 ? 27.182  -61.804 -37.789 1.00 48.00  ? 185 ASP D CA  1 
ATOM   6313 C C   . ASP D 4 185 ? 26.464  -62.683 -36.774 1.00 49.64  ? 185 ASP D C   1 
ATOM   6314 O O   . ASP D 4 185 ? 27.055  -63.055 -35.754 1.00 52.15  ? 185 ASP D O   1 
ATOM   6315 C CB  . ASP D 4 185 ? 27.088  -60.335 -37.376 1.00 47.01  ? 185 ASP D CB  1 
ATOM   6316 C CG  . ASP D 4 185 ? 28.368  -59.568 -37.644 1.00 78.39  ? 185 ASP D CG  1 
ATOM   6317 O OD1 . ASP D 4 185 ? 29.321  -59.715 -36.852 1.00 78.58  ? 185 ASP D OD1 1 
ATOM   6318 O OD2 . ASP D 4 185 ? 28.420  -58.825 -38.647 1.00 78.94  ? 185 ASP D OD2 1 
ATOM   6319 N N   . TYR D 4 186 ? 25.199  -63.026 -37.032 1.00 44.36  ? 186 TYR D N   1 
ATOM   6320 C CA  . TYR D 4 186 ? 24.443  -63.837 -36.084 1.00 48.24  ? 186 TYR D CA  1 
ATOM   6321 C C   . TYR D 4 186 ? 25.041  -65.230 -35.935 1.00 59.72  ? 186 TYR D C   1 
ATOM   6322 O O   . TYR D 4 186 ? 25.104  -65.769 -34.824 1.00 58.70  ? 186 TYR D O   1 
ATOM   6323 C CB  . TYR D 4 186 ? 22.980  -63.924 -36.515 1.00 45.27  ? 186 TYR D CB  1 
ATOM   6324 C CG  . TYR D 4 186 ? 22.141  -64.775 -35.594 1.00 49.03  ? 186 TYR D CG  1 
ATOM   6325 C CD1 . TYR D 4 186 ? 21.909  -64.386 -34.282 1.00 46.67  ? 186 TYR D CD1 1 
ATOM   6326 C CD2 . TYR D 4 186 ? 21.585  -65.968 -36.033 1.00 49.50  ? 186 TYR D CD2 1 
ATOM   6327 C CE1 . TYR D 4 186 ? 21.147  -65.162 -33.432 1.00 47.47  ? 186 TYR D CE1 1 
ATOM   6328 C CE2 . TYR D 4 186 ? 20.820  -66.750 -35.191 1.00 53.27  ? 186 TYR D CE2 1 
ATOM   6329 C CZ  . TYR D 4 186 ? 20.606  -66.344 -33.891 1.00 48.14  ? 186 TYR D CZ  1 
ATOM   6330 O OH  . TYR D 4 186 ? 19.843  -67.119 -33.050 1.00 58.31  ? 186 TYR D OH  1 
ATOM   6331 N N   . GLU D 4 187 ? 25.488  -65.828 -37.036 1.00 62.39  ? 187 GLU D N   1 
ATOM   6332 C CA  . GLU D 4 187 ? 26.065  -67.164 -37.006 1.00 63.88  ? 187 GLU D CA  1 
ATOM   6333 C C   . GLU D 4 187 ? 27.558  -67.163 -36.698 1.00 59.72  ? 187 GLU D C   1 
ATOM   6334 O O   . GLU D 4 187 ? 28.164  -68.238 -36.650 1.00 62.45  ? 187 GLU D O   1 
ATOM   6335 C CB  . GLU D 4 187 ? 25.799  -67.882 -38.333 1.00 83.39  ? 187 GLU D CB  1 
ATOM   6336 C CG  . GLU D 4 187 ? 24.406  -68.488 -38.422 1.00 79.18  ? 187 GLU D CG  1 
ATOM   6337 C CD  . GLU D 4 187 ? 23.575  -67.914 -39.551 1.00 84.78  ? 187 GLU D CD  1 
ATOM   6338 O OE1 . GLU D 4 187 ? 24.147  -67.253 -40.443 1.00 85.12  ? 187 GLU D OE1 1 
ATOM   6339 O OE2 . GLU D 4 187 ? 22.344  -68.126 -39.545 1.00 76.17  ? 187 GLU D OE2 1 
ATOM   6340 N N   . LYS D 4 188 ? 28.160  -65.995 -36.477 1.00 59.93  ? 188 LYS D N   1 
ATOM   6341 C CA  . LYS D 4 188 ? 29.543  -65.918 -36.022 1.00 56.88  ? 188 LYS D CA  1 
ATOM   6342 C C   . LYS D 4 188 ? 29.670  -66.079 -34.514 1.00 44.65  ? 188 LYS D C   1 
ATOM   6343 O O   . LYS D 4 188 ? 30.783  -65.987 -33.986 1.00 65.42  ? 188 LYS D O   1 
ATOM   6344 C CB  . LYS D 4 188 ? 30.174  -64.590 -36.449 1.00 52.67  ? 188 LYS D CB  1 
ATOM   6345 C CG  . LYS D 4 188 ? 30.035  -64.296 -37.928 1.00 57.77  ? 188 LYS D CG  1 
ATOM   6346 C CD  . LYS D 4 188 ? 30.987  -63.211 -38.392 1.00 53.28  ? 188 LYS D CD  1 
ATOM   6347 C CE  . LYS D 4 188 ? 32.054  -63.796 -39.299 1.00 66.11  ? 188 LYS D CE  1 
ATOM   6348 N NZ  . LYS D 4 188 ? 32.769  -64.919 -38.631 1.00 59.95  ? 188 LYS D NZ  1 
ATOM   6349 N N   . HIS D 4 189 ? 28.559  -66.305 -33.818 1.00 48.71  ? 189 HIS D N   1 
ATOM   6350 C CA  . HIS D 4 189 ? 28.547  -66.483 -32.375 1.00 54.35  ? 189 HIS D CA  1 
ATOM   6351 C C   . HIS D 4 189 ? 27.598  -67.623 -32.041 1.00 50.84  ? 189 HIS D C   1 
ATOM   6352 O O   . HIS D 4 189 ? 26.770  -68.023 -32.862 1.00 49.38  ? 189 HIS D O   1 
ATOM   6353 C CB  . HIS D 4 189 ? 28.125  -65.198 -31.656 1.00 53.22  ? 189 HIS D CB  1 
ATOM   6354 C CG  . HIS D 4 189 ? 28.832  -63.971 -32.145 1.00 64.28  ? 189 HIS D CG  1 
ATOM   6355 N ND1 . HIS D 4 189 ? 28.247  -63.067 -33.004 1.00 54.30  ? 189 HIS D ND1 1 
ATOM   6356 C CD2 . HIS D 4 189 ? 30.079  -63.505 -31.900 1.00 62.96  ? 189 HIS D CD2 1 
ATOM   6357 C CE1 . HIS D 4 189 ? 29.102  -62.093 -33.265 1.00 58.25  ? 189 HIS D CE1 1 
ATOM   6358 N NE2 . HIS D 4 189 ? 30.221  -62.335 -32.607 1.00 74.99  ? 189 HIS D NE2 1 
ATOM   6359 N N   . LYS D 4 190 ? 27.727  -68.153 -30.825 1.00 43.32  ? 190 LYS D N   1 
ATOM   6360 C CA  . LYS D 4 190 ? 26.944  -69.309 -30.406 1.00 51.65  ? 190 LYS D CA  1 
ATOM   6361 C C   . LYS D 4 190 ? 25.972  -69.002 -29.276 1.00 53.87  ? 190 LYS D C   1 
ATOM   6362 O O   . LYS D 4 190 ? 24.780  -69.305 -29.394 1.00 56.32  ? 190 LYS D O   1 
ATOM   6363 C CB  . LYS D 4 190 ? 27.876  -70.453 -29.980 1.00 53.97  ? 190 LYS D CB  1 
ATOM   6364 C CG  . LYS D 4 190 ? 27.405  -71.833 -30.422 1.00 57.63  ? 190 LYS D CG  1 
ATOM   6365 C CD  . LYS D 4 190 ? 27.965  -72.189 -31.791 1.00 69.26  ? 190 LYS D CD  1 
ATOM   6366 C CE  . LYS D 4 190 ? 27.107  -73.232 -32.492 1.00 79.70  ? 190 LYS D CE  1 
ATOM   6367 N NZ  . LYS D 4 190 ? 27.705  -73.652 -33.792 1.00 48.46  ? 190 LYS D NZ  1 
ATOM   6368 N N   . VAL D 4 191 ? 26.441  -68.407 -28.182 1.00 51.35  ? 191 VAL D N   1 
ATOM   6369 C CA  . VAL D 4 191 ? 25.633  -68.211 -26.982 1.00 44.31  ? 191 VAL D CA  1 
ATOM   6370 C C   . VAL D 4 191 ? 25.167  -66.763 -26.922 1.00 32.48  ? 191 VAL D C   1 
ATOM   6371 O O   . VAL D 4 191 ? 25.983  -65.835 -26.991 1.00 38.66  ? 191 VAL D O   1 
ATOM   6372 C CB  . VAL D 4 191 ? 26.418  -68.589 -25.715 1.00 39.85  ? 191 VAL D CB  1 
ATOM   6373 C CG1 . VAL D 4 191 ? 25.529  -68.470 -24.485 1.00 35.96  ? 191 VAL D CG1 1 
ATOM   6374 C CG2 . VAL D 4 191 ? 26.980  -69.997 -25.841 1.00 43.61  ? 191 VAL D CG2 1 
ATOM   6375 N N   . TYR D 4 192 ? 23.856  -66.571 -26.788 1.00 41.26  ? 192 TYR D N   1 
ATOM   6376 C CA  . TYR D 4 192 ? 23.243  -65.249 -26.691 1.00 39.84  ? 192 TYR D CA  1 
ATOM   6377 C C   . TYR D 4 192 ? 22.540  -65.149 -25.344 1.00 37.89  ? 192 TYR D C   1 
ATOM   6378 O O   . TYR D 4 192 ? 21.523  -65.815 -25.119 1.00 36.20  ? 192 TYR D O   1 
ATOM   6379 C CB  . TYR D 4 192 ? 22.266  -65.013 -27.842 1.00 27.45  ? 192 TYR D CB  1 
ATOM   6380 C CG  . TYR D 4 192 ? 22.938  -64.879 -29.188 1.00 32.91  ? 192 TYR D CG  1 
ATOM   6381 C CD1 . TYR D 4 192 ? 23.395  -65.997 -29.873 1.00 32.17  ? 192 TYR D CD1 1 
ATOM   6382 C CD2 . TYR D 4 192 ? 23.116  -63.633 -29.774 1.00 35.45  ? 192 TYR D CD2 1 
ATOM   6383 C CE1 . TYR D 4 192 ? 24.011  -65.877 -31.102 1.00 46.25  ? 192 TYR D CE1 1 
ATOM   6384 C CE2 . TYR D 4 192 ? 23.731  -63.503 -31.003 1.00 39.43  ? 192 TYR D CE2 1 
ATOM   6385 C CZ  . TYR D 4 192 ? 24.176  -64.628 -31.663 1.00 48.72  ? 192 TYR D CZ  1 
ATOM   6386 O OH  . TYR D 4 192 ? 24.790  -64.503 -32.887 1.00 52.02  ? 192 TYR D OH  1 
ATOM   6387 N N   . ALA D 4 193 ? 23.072  -64.314 -24.456 1.00 39.94  ? 193 ALA D N   1 
ATOM   6388 C CA  . ALA D 4 193 ? 22.591  -64.216 -23.087 1.00 40.98  ? 193 ALA D CA  1 
ATOM   6389 C C   . ALA D 4 193 ? 22.083  -62.810 -22.796 1.00 43.34  ? 193 ALA D C   1 
ATOM   6390 O O   . ALA D 4 193 ? 22.550  -61.826 -23.379 1.00 29.47  ? 193 ALA D O   1 
ATOM   6391 C CB  . ALA D 4 193 ? 23.692  -64.586 -22.085 1.00 33.46  ? 193 ALA D CB  1 
ATOM   6392 N N   . CYS D 4 194 ? 21.115  -62.730 -21.885 1.00 48.64  ? 194 CYS D N   1 
ATOM   6393 C CA  . CYS D 4 194 ? 20.529  -61.469 -21.448 1.00 48.09  ? 194 CYS D CA  1 
ATOM   6394 C C   . CYS D 4 194 ? 20.559  -61.427 -19.929 1.00 50.48  ? 194 CYS D C   1 
ATOM   6395 O O   . CYS D 4 194 ? 19.908  -62.246 -19.272 1.00 42.90  ? 194 CYS D O   1 
ATOM   6396 C CB  . CYS D 4 194 ? 19.094  -61.323 -21.965 1.00 43.06  ? 194 CYS D CB  1 
ATOM   6397 S SG  . CYS D 4 194 ? 18.176  -59.930 -21.275 1.00 96.22  ? 194 CYS D SG  1 
ATOM   6398 N N   . GLU D 4 195 ? 21.307  -60.478 -19.373 1.00 45.45  ? 195 GLU D N   1 
ATOM   6399 C CA  . GLU D 4 195 ? 21.486  -60.355 -17.933 1.00 42.11  ? 195 GLU D CA  1 
ATOM   6400 C C   . GLU D 4 195 ? 20.737  -59.127 -17.434 1.00 44.77  ? 195 GLU D C   1 
ATOM   6401 O O   . GLU D 4 195 ? 20.845  -58.046 -18.022 1.00 43.41  ? 195 GLU D O   1 
ATOM   6402 C CB  . GLU D 4 195 ? 22.971  -60.263 -17.576 1.00 45.28  ? 195 GLU D CB  1 
ATOM   6403 C CG  . GLU D 4 195 ? 23.259  -60.339 -16.088 1.00 52.65  ? 195 GLU D CG  1 
ATOM   6404 C CD  . GLU D 4 195 ? 24.744  -60.402 -15.788 1.00 72.00  ? 195 GLU D CD  1 
ATOM   6405 O OE1 . GLU D 4 195 ? 25.470  -61.113 -16.515 1.00 71.54  ? 195 GLU D OE1 1 
ATOM   6406 O OE2 . GLU D 4 195 ? 25.184  -59.733 -14.829 1.00 70.90  ? 195 GLU D OE2 1 
ATOM   6407 N N   . VAL D 4 196 ? 19.979  -59.297 -16.352 1.00 52.45  ? 196 VAL D N   1 
ATOM   6408 C CA  . VAL D 4 196 ? 19.083  -58.265 -15.845 1.00 50.11  ? 196 VAL D CA  1 
ATOM   6409 C C   . VAL D 4 196 ? 19.387  -58.015 -14.374 1.00 44.02  ? 196 VAL D C   1 
ATOM   6410 O O   . VAL D 4 196 ? 19.440  -58.958 -13.576 1.00 42.55  ? 196 VAL D O   1 
ATOM   6411 C CB  . VAL D 4 196 ? 17.605  -58.659 -16.030 1.00 48.09  ? 196 VAL D CB  1 
ATOM   6412 C CG1 . VAL D 4 196 ? 16.699  -57.690 -15.290 1.00 51.34  ? 196 VAL D CG1 1 
ATOM   6413 C CG2 . VAL D 4 196 ? 17.253  -58.704 -17.508 1.00 45.96  ? 196 VAL D CG2 1 
ATOM   6414 N N   . THR D 4 197 ? 19.578  -56.747 -14.020 1.00 47.40  ? 197 THR D N   1 
ATOM   6415 C CA  . THR D 4 197 ? 19.736  -56.313 -12.639 1.00 49.80  ? 197 THR D CA  1 
ATOM   6416 C C   . THR D 4 197 ? 18.508  -55.506 -12.240 1.00 44.53  ? 197 THR D C   1 
ATOM   6417 O O   . THR D 4 197 ? 18.106  -54.588 -12.962 1.00 48.81  ? 197 THR D O   1 
ATOM   6418 C CB  . THR D 4 197 ? 21.003  -55.471 -12.465 1.00 44.92  ? 197 THR D CB  1 
ATOM   6419 O OG1 . THR D 4 197 ? 22.142  -56.222 -12.903 1.00 46.65  ? 197 THR D OG1 1 
ATOM   6420 C CG2 . THR D 4 197 ? 21.190  -55.079 -11.006 1.00 50.60  ? 197 THR D CG2 1 
ATOM   6421 N N   . HIS D 4 198 ? 17.913  -55.848 -11.098 1.00 56.66  ? 198 HIS D N   1 
ATOM   6422 C CA  . HIS D 4 198 ? 16.676  -55.207 -10.676 1.00 57.84  ? 198 HIS D CA  1 
ATOM   6423 C C   . HIS D 4 198 ? 16.595  -55.200 -9.156  1.00 53.85  ? 198 HIS D C   1 
ATOM   6424 O O   . HIS D 4 198 ? 17.310  -55.937 -8.470  1.00 50.81  ? 198 HIS D O   1 
ATOM   6425 C CB  . HIS D 4 198 ? 15.452  -55.910 -11.280 1.00 57.07  ? 198 HIS D CB  1 
ATOM   6426 C CG  . HIS D 4 198 ? 14.169  -55.163 -11.086 1.00 54.22  ? 198 HIS D CG  1 
ATOM   6427 N ND1 . HIS D 4 198 ? 13.206  -55.560 -10.185 1.00 61.00  ? 198 HIS D ND1 1 
ATOM   6428 C CD2 . HIS D 4 198 ? 13.696  -54.038 -11.672 1.00 58.24  ? 198 HIS D CD2 1 
ATOM   6429 C CE1 . HIS D 4 198 ? 12.191  -54.715 -10.227 1.00 62.76  ? 198 HIS D CE1 1 
ATOM   6430 N NE2 . HIS D 4 198 ? 12.463  -53.782 -11.122 1.00 61.16  ? 198 HIS D NE2 1 
ATOM   6431 N N   . GLN D 4 199 ? 15.713  -54.340 -8.638  1.00 59.04  ? 199 GLN D N   1 
ATOM   6432 C CA  . GLN D 4 199 ? 15.494  -54.257 -7.197  1.00 52.20  ? 199 GLN D CA  1 
ATOM   6433 C C   . GLN D 4 199 ? 15.014  -55.589 -6.633  1.00 54.64  ? 199 GLN D C   1 
ATOM   6434 O O   . GLN D 4 199 ? 15.528  -56.068 -5.616  1.00 53.67  ? 199 GLN D O   1 
ATOM   6435 C CB  . GLN D 4 199 ? 14.481  -53.154 -6.889  1.00 66.08  ? 199 GLN D CB  1 
ATOM   6436 C CG  . GLN D 4 199 ? 15.086  -51.775 -6.717  1.00 72.30  ? 199 GLN D CG  1 
ATOM   6437 C CD  . GLN D 4 199 ? 15.682  -51.575 -5.339  1.00 76.19  ? 199 GLN D CD  1 
ATOM   6438 O OE1 . GLN D 4 199 ? 15.181  -52.111 -4.349  1.00 63.73  ? 199 GLN D OE1 1 
ATOM   6439 N NE2 . GLN D 4 199 ? 16.759  -50.803 -5.267  1.00 65.93  ? 199 GLN D NE2 1 
ATOM   6440 N N   . GLY D 4 200 ? 14.032  -56.207 -7.289  1.00 58.46  ? 200 GLY D N   1 
ATOM   6441 C CA  . GLY D 4 200 ? 13.484  -57.464 -6.815  1.00 57.78  ? 200 GLY D CA  1 
ATOM   6442 C C   . GLY D 4 200 ? 14.405  -58.652 -6.978  1.00 55.97  ? 200 GLY D C   1 
ATOM   6443 O O   . GLY D 4 200 ? 14.096  -59.730 -6.459  1.00 60.67  ? 200 GLY D O   1 
ATOM   6444 N N   . LEU D 4 201 ? 15.520  -58.483 -7.682  1.00 58.88  ? 201 LEU D N   1 
ATOM   6445 C CA  . LEU D 4 201 ? 16.503  -59.540 -7.867  1.00 68.86  ? 201 LEU D CA  1 
ATOM   6446 C C   . LEU D 4 201 ? 17.659  -59.308 -6.902  1.00 64.09  ? 201 LEU D C   1 
ATOM   6447 O O   . LEU D 4 201 ? 18.357  -58.292 -6.997  1.00 68.11  ? 201 LEU D O   1 
ATOM   6448 C CB  . LEU D 4 201 ? 17.003  -59.570 -9.311  1.00 70.74  ? 201 LEU D CB  1 
ATOM   6449 C CG  . LEU D 4 201 ? 15.932  -59.717 -10.392 1.00 65.37  ? 201 LEU D CG  1 
ATOM   6450 C CD1 . LEU D 4 201 ? 16.555  -59.671 -11.779 1.00 54.39  ? 201 LEU D CD1 1 
ATOM   6451 C CD2 . LEU D 4 201 ? 15.151  -61.006 -10.191 1.00 55.29  ? 201 LEU D CD2 1 
ATOM   6452 N N   . SER D 4 202 ? 17.855  -60.247 -5.973  1.00 62.06  ? 202 SER D N   1 
ATOM   6453 C CA  . SER D 4 202 ? 18.997  -60.161 -5.070  1.00 72.10  ? 202 SER D CA  1 
ATOM   6454 C C   . SER D 4 202 ? 20.306  -60.253 -5.843  1.00 75.06  ? 202 SER D C   1 
ATOM   6455 O O   . SER D 4 202 ? 21.275  -59.551 -5.531  1.00 78.40  ? 202 SER D O   1 
ATOM   6456 C CB  . SER D 4 202 ? 18.914  -61.263 -4.013  1.00 72.04  ? 202 SER D CB  1 
ATOM   6457 O OG  . SER D 4 202 ? 18.929  -62.547 -4.612  1.00 67.83  ? 202 SER D OG  1 
ATOM   6458 N N   . SER D 4 203 ? 20.349  -61.110 -6.857  1.00 66.75  ? 203 SER D N   1 
ATOM   6459 C CA  . SER D 4 203 ? 21.481  -61.257 -7.753  1.00 57.51  ? 203 SER D CA  1 
ATOM   6460 C C   . SER D 4 203 ? 20.994  -61.165 -9.190  1.00 57.73  ? 203 SER D C   1 
ATOM   6461 O O   . SER D 4 203 ? 19.828  -61.459 -9.472  1.00 64.21  ? 203 SER D O   1 
ATOM   6462 C CB  . SER D 4 203 ? 22.197  -62.599 -7.529  1.00 54.34  ? 203 SER D CB  1 
ATOM   6463 O OG  . SER D 4 203 ? 21.295  -63.685 -7.648  1.00 67.66  ? 203 SER D OG  1 
ATOM   6464 N N   . PRO D 4 204 ? 21.857  -60.742 -10.115 1.00 42.64  ? 204 PRO D N   1 
ATOM   6465 C CA  . PRO D 4 204 ? 21.431  -60.619 -11.514 1.00 48.92  ? 204 PRO D CA  1 
ATOM   6466 C C   . PRO D 4 204 ? 20.947  -61.947 -12.079 1.00 44.59  ? 204 PRO D C   1 
ATOM   6467 O O   . PRO D 4 204 ? 21.470  -63.014 -11.751 1.00 59.80  ? 204 PRO D O   1 
ATOM   6468 C CB  . PRO D 4 204 ? 22.698  -60.133 -12.226 1.00 53.26  ? 204 PRO D CB  1 
ATOM   6469 C CG  . PRO D 4 204 ? 23.470  -59.428 -11.165 1.00 56.64  ? 204 PRO D CG  1 
ATOM   6470 C CD  . PRO D 4 204 ? 23.206  -60.191 -9.898  1.00 47.23  ? 204 PRO D CD  1 
ATOM   6471 N N   . VAL D 4 205 ? 19.933  -61.867 -12.937 1.00 42.43  ? 205 VAL D N   1 
ATOM   6472 C CA  . VAL D 4 205 ? 19.328  -63.029 -13.577 1.00 51.44  ? 205 VAL D CA  1 
ATOM   6473 C C   . VAL D 4 205 ? 19.734  -63.033 -15.044 1.00 50.72  ? 205 VAL D C   1 
ATOM   6474 O O   . VAL D 4 205 ? 19.597  -62.015 -15.734 1.00 55.67  ? 205 VAL D O   1 
ATOM   6475 C CB  . VAL D 4 205 ? 17.796  -63.021 -13.429 1.00 45.12  ? 205 VAL D CB  1 
ATOM   6476 C CG1 . VAL D 4 205 ? 17.166  -64.063 -14.339 1.00 40.19  ? 205 VAL D CG1 1 
ATOM   6477 C CG2 . VAL D 4 205 ? 17.406  -63.270 -11.982 1.00 41.18  ? 205 VAL D CG2 1 
ATOM   6478 N N   . THR D 4 206 ? 20.236  -64.171 -15.516 1.00 44.04  ? 206 THR D N   1 
ATOM   6479 C CA  . THR D 4 206 ? 20.683  -64.323 -16.893 1.00 46.46  ? 206 THR D CA  1 
ATOM   6480 C C   . THR D 4 206 ? 19.875  -65.414 -17.580 1.00 51.07  ? 206 THR D C   1 
ATOM   6481 O O   . THR D 4 206 ? 19.741  -66.522 -17.050 1.00 55.71  ? 206 THR D O   1 
ATOM   6482 C CB  . THR D 4 206 ? 22.175  -64.659 -16.957 1.00 53.70  ? 206 THR D CB  1 
ATOM   6483 O OG1 . THR D 4 206 ? 22.929  -63.619 -16.320 1.00 60.92  ? 206 THR D OG1 1 
ATOM   6484 C CG2 . THR D 4 206 ? 22.626  -64.793 -18.405 1.00 39.33  ? 206 THR D CG2 1 
ATOM   6485 N N   . LYS D 4 207 ? 19.336  -65.093 -18.753 1.00 50.89  ? 207 LYS D N   1 
ATOM   6486 C CA  . LYS D 4 207 ? 18.671  -66.056 -19.620 1.00 47.53  ? 207 LYS D CA  1 
ATOM   6487 C C   . LYS D 4 207 ? 19.434  -66.130 -20.934 1.00 55.22  ? 207 LYS D C   1 
ATOM   6488 O O   . LYS D 4 207 ? 19.732  -65.096 -21.540 1.00 58.04  ? 207 LYS D O   1 
ATOM   6489 C CB  . LYS D 4 207 ? 17.212  -65.665 -19.867 1.00 37.43  ? 207 LYS D CB  1 
ATOM   6490 C CG  . LYS D 4 207 ? 16.267  -66.018 -18.730 1.00 37.23  ? 207 LYS D CG  1 
ATOM   6491 C CD  . LYS D 4 207 ? 15.990  -67.512 -18.692 1.00 69.51  ? 207 LYS D CD  1 
ATOM   6492 C CE  . LYS D 4 207 ? 14.817  -67.834 -17.781 1.00 64.42  ? 207 LYS D CE  1 
ATOM   6493 N NZ  . LYS D 4 207 ? 14.282  -69.197 -18.050 1.00 48.59  ? 207 LYS D NZ  1 
ATOM   6494 N N   . SER D 4 208 ? 19.748  -67.348 -21.371 1.00 51.05  ? 208 SER D N   1 
ATOM   6495 C CA  . SER D 4 208 ? 20.585  -67.547 -22.544 1.00 56.19  ? 208 SER D CA  1 
ATOM   6496 C C   . SER D 4 208 ? 20.030  -68.682 -23.393 1.00 54.67  ? 208 SER D C   1 
ATOM   6497 O O   . SER D 4 208 ? 19.236  -69.504 -22.931 1.00 62.52  ? 208 SER D O   1 
ATOM   6498 C CB  . SER D 4 208 ? 22.038  -67.851 -22.155 1.00 56.48  ? 208 SER D CB  1 
ATOM   6499 O OG  . SER D 4 208 ? 22.127  -69.063 -21.426 1.00 51.43  ? 208 SER D OG  1 
ATOM   6500 N N   . PHE D 4 209 ? 20.460  -68.708 -24.654 1.00 52.01  ? 209 PHE D N   1 
ATOM   6501 C CA  . PHE D 4 209 ? 20.104  -69.779 -25.573 1.00 36.38  ? 209 PHE D CA  1 
ATOM   6502 C C   . PHE D 4 209 ? 21.249  -69.997 -26.551 1.00 48.37  ? 209 PHE D C   1 
ATOM   6503 O O   . PHE D 4 209 ? 21.934  -69.050 -26.950 1.00 53.22  ? 209 PHE D O   1 
ATOM   6504 C CB  . PHE D 4 209 ? 18.808  -69.469 -26.334 1.00 32.31  ? 209 PHE D CB  1 
ATOM   6505 C CG  . PHE D 4 209 ? 18.907  -68.281 -27.255 1.00 44.59  ? 209 PHE D CG  1 
ATOM   6506 C CD1 . PHE D 4 209 ? 18.611  -67.008 -26.799 1.00 52.82  ? 209 PHE D CD1 1 
ATOM   6507 C CD2 . PHE D 4 209 ? 19.283  -68.439 -28.580 1.00 42.20  ? 209 PHE D CD2 1 
ATOM   6508 C CE1 . PHE D 4 209 ? 18.697  -65.916 -27.644 1.00 47.66  ? 209 PHE D CE1 1 
ATOM   6509 C CE2 . PHE D 4 209 ? 19.375  -67.351 -29.427 1.00 47.28  ? 209 PHE D CE2 1 
ATOM   6510 C CZ  . PHE D 4 209 ? 19.079  -66.088 -28.960 1.00 39.56  ? 209 PHE D CZ  1 
ATOM   6511 N N   . ASN D 4 210 ? 21.449  -71.256 -26.932 1.00 59.08  ? 210 ASN D N   1 
ATOM   6512 C CA  . ASN D 4 210 ? 22.381  -71.596 -27.993 1.00 47.80  ? 210 ASN D CA  1 
ATOM   6513 C C   . ASN D 4 210 ? 21.709  -71.395 -29.350 1.00 52.17  ? 210 ASN D C   1 
ATOM   6514 O O   . ASN D 4 210 ? 20.513  -71.108 -29.444 1.00 68.96  ? 210 ASN D O   1 
ATOM   6515 C CB  . ASN D 4 210 ? 22.875  -73.031 -27.827 1.00 52.88  ? 210 ASN D CB  1 
ATOM   6516 C CG  . ASN D 4 210 ? 23.748  -73.212 -26.598 1.00 55.71  ? 210 ASN D CG  1 
ATOM   6517 O OD1 . ASN D 4 210 ? 23.317  -72.961 -25.471 1.00 44.94  ? 210 ASN D OD1 1 
ATOM   6518 N ND2 . ASN D 4 210 ? 24.980  -73.660 -26.809 1.00 59.84  ? 210 ASN D ND2 1 
ATOM   6519 N N   . ARG D 4 211 ? 22.482  -71.552 -30.420 1.00 57.42  ? 211 ARG D N   1 
ATOM   6520 C CA  . ARG D 4 211 ? 21.973  -71.393 -31.782 1.00 60.51  ? 211 ARG D CA  1 
ATOM   6521 C C   . ARG D 4 211 ? 21.607  -72.772 -32.320 1.00 70.70  ? 211 ARG D C   1 
ATOM   6522 O O   . ARG D 4 211 ? 22.416  -73.450 -32.955 1.00 74.51  ? 211 ARG D O   1 
ATOM   6523 C CB  . ARG D 4 211 ? 22.998  -70.695 -32.665 1.00 58.57  ? 211 ARG D CB  1 
ATOM   6524 C CG  . ARG D 4 211 ? 22.846  -69.185 -32.701 1.00 53.44  ? 211 ARG D CG  1 
ATOM   6525 C CD  . ARG D 4 211 ? 23.800  -68.544 -33.699 1.00 63.70  ? 211 ARG D CD  1 
ATOM   6526 N NE  . ARG D 4 211 ? 23.959  -69.348 -34.906 1.00 55.07  ? 211 ARG D NE  1 
ATOM   6527 C CZ  . ARG D 4 211 ? 25.051  -70.038 -35.208 1.00 63.48  ? 211 ARG D CZ  1 
ATOM   6528 N NH1 . ARG D 4 211 ? 26.123  -70.011 -34.433 1.00 67.33  ? 211 ARG D NH1 1 
ATOM   6529 N NH2 . ARG D 4 211 ? 25.067  -70.777 -36.313 1.00 66.06  ? 211 ARG D NH2 1 
ATOM   6530 N N   . GLY D 4 212 ? 20.367  -73.181 -32.069 1.00 70.21  ? 212 GLY D N   1 
ATOM   6531 C CA  . GLY D 4 212 ? 19.877  -74.469 -32.525 1.00 51.63  ? 212 GLY D CA  1 
ATOM   6532 C C   . GLY D 4 212 ? 19.149  -75.242 -31.445 1.00 51.31  ? 212 GLY D C   1 
ATOM   6533 O O   . GLY D 4 212 ? 19.650  -75.390 -30.330 1.00 68.77  ? 212 GLY D O   1 
ATOM   6534 N N   . ASN E 5 2   ? -17.802 30.380  -23.011 1.00 82.56  ? 334 ASN A N   1 
ATOM   6535 C CA  . ASN E 5 2   ? -18.427 29.109  -23.360 1.00 75.69  ? 334 ASN A CA  1 
ATOM   6536 C C   . ASN E 5 2   ? -17.402 28.109  -23.891 1.00 74.01  ? 334 ASN A C   1 
ATOM   6537 O O   . ASN E 5 2   ? -17.317 27.872  -25.096 1.00 80.79  ? 334 ASN A O   1 
ATOM   6538 C CB  . ASN E 5 2   ? -19.537 29.329  -24.389 1.00 68.45  ? 334 ASN A CB  1 
ATOM   6539 C CG  . ASN E 5 2   ? -19.161 30.355  -25.441 1.00 82.35  ? 334 ASN A CG  1 
ATOM   6540 O OD1 . ASN E 5 2   ? -18.392 31.279  -25.175 1.00 77.94  ? 334 ASN A OD1 1 
ATOM   6541 N ND2 . ASN E 5 2   ? -19.705 30.198  -26.643 1.00 69.99  ? 334 ASN A ND2 1 
ATOM   6542 N N   . LEU E 5 3   ? -16.631 27.525  -22.979 1.00 74.44  ? 335 LEU A N   1 
ATOM   6543 C CA  . LEU E 5 3   ? -15.606 26.553  -23.328 1.00 78.53  ? 335 LEU A CA  1 
ATOM   6544 C C   . LEU E 5 3   ? -16.203 25.149  -23.398 1.00 81.18  ? 335 LEU A C   1 
ATOM   6545 O O   . LEU E 5 3   ? -17.235 24.854  -22.792 1.00 83.38  ? 335 LEU A O   1 
ATOM   6546 C CB  . LEU E 5 3   ? -14.464 26.590  -22.311 1.00 78.50  ? 335 LEU A CB  1 
ATOM   6547 C CG  . LEU E 5 3   ? -13.049 26.345  -22.837 1.00 80.77  ? 335 LEU A CG  1 
ATOM   6548 C CD1 . LEU E 5 3   ? -12.566 27.542  -23.644 1.00 74.00  ? 335 LEU A CD1 1 
ATOM   6549 C CD2 . LEU E 5 3   ? -12.087 26.038  -21.698 1.00 59.35  ? 335 LEU A CD2 1 
ATOM   6550 N N   . CYS E 5 4   ? -15.533 24.279  -24.154 1.00 76.60  ? 336 CYS A N   1 
ATOM   6551 C CA  . CYS E 5 4   ? -16.026 22.916  -24.308 1.00 68.57  ? 336 CYS A CA  1 
ATOM   6552 C C   . CYS E 5 4   ? -15.757 22.104  -23.041 1.00 61.06  ? 336 CYS A C   1 
ATOM   6553 O O   . CYS E 5 4   ? -14.720 22.280  -22.397 1.00 68.13  ? 336 CYS A O   1 
ATOM   6554 C CB  . CYS E 5 4   ? -15.374 22.243  -25.513 1.00 77.13  ? 336 CYS A CB  1 
ATOM   6555 S SG  . CYS E 5 4   ? -15.792 23.028  -27.090 1.00 99.61  ? 336 CYS A SG  1 
ATOM   6556 N N   . PRO E 5 5   ? -16.673 21.203  -22.666 1.00 57.88  ? 337 PRO A N   1 
ATOM   6557 C CA  . PRO E 5 5   ? -16.554 20.467  -21.394 1.00 63.91  ? 337 PRO A CA  1 
ATOM   6558 C C   . PRO E 5 5   ? -15.647 19.243  -21.493 1.00 57.56  ? 337 PRO A C   1 
ATOM   6559 O O   . PRO E 5 5   ? -16.040 18.114  -21.183 1.00 60.57  ? 337 PRO A O   1 
ATOM   6560 C CB  . PRO E 5 5   ? -18.013 20.093  -21.102 1.00 59.44  ? 337 PRO A CB  1 
ATOM   6561 C CG  . PRO E 5 5   ? -18.604 19.892  -22.457 1.00 55.05  ? 337 PRO A CG  1 
ATOM   6562 C CD  . PRO E 5 5   ? -17.937 20.901  -23.363 1.00 51.62  ? 337 PRO A CD  1 
ATOM   6563 N N   . PHE E 5 6   ? -14.403 19.468  -21.923 1.00 52.34  ? 338 PHE A N   1 
ATOM   6564 C CA  . PHE E 5 6   ? -13.440 18.374  -21.986 1.00 48.87  ? 338 PHE A CA  1 
ATOM   6565 C C   . PHE E 5 6   ? -13.054 17.883  -20.598 1.00 53.10  ? 338 PHE A C   1 
ATOM   6566 O O   . PHE E 5 6   ? -12.710 16.707  -20.431 1.00 51.24  ? 338 PHE A O   1 
ATOM   6567 C CB  . PHE E 5 6   ? -12.194 18.810  -22.755 1.00 52.12  ? 338 PHE A CB  1 
ATOM   6568 C CG  . PHE E 5 6   ? -12.343 18.729  -24.245 1.00 58.56  ? 338 PHE A CG  1 
ATOM   6569 C CD1 . PHE E 5 6   ? -13.153 17.765  -24.821 1.00 60.11  ? 338 PHE A CD1 1 
ATOM   6570 C CD2 . PHE E 5 6   ? -11.675 19.617  -25.071 1.00 75.08  ? 338 PHE A CD2 1 
ATOM   6571 C CE1 . PHE E 5 6   ? -13.291 17.687  -26.192 1.00 54.60  ? 338 PHE A CE1 1 
ATOM   6572 C CE2 . PHE E 5 6   ? -11.811 19.544  -26.443 1.00 68.27  ? 338 PHE A CE2 1 
ATOM   6573 C CZ  . PHE E 5 6   ? -12.621 18.579  -27.004 1.00 60.19  ? 338 PHE A CZ  1 
ATOM   6574 N N   . GLY E 5 7   ? -13.098 18.763  -19.596 1.00 57.13  ? 339 GLY A N   1 
ATOM   6575 C CA  . GLY E 5 7   ? -12.731 18.359  -18.252 1.00 49.19  ? 339 GLY A CA  1 
ATOM   6576 C C   . GLY E 5 7   ? -13.661 17.322  -17.657 1.00 49.41  ? 339 GLY A C   1 
ATOM   6577 O O   . GLY E 5 7   ? -13.229 16.486  -16.862 1.00 50.67  ? 339 GLY A O   1 
ATOM   6578 N N   . GLU E 5 8   ? -14.942 17.355  -18.032 1.00 50.25  ? 340 GLU A N   1 
ATOM   6579 C CA  . GLU E 5 8   ? -15.898 16.410  -17.465 1.00 48.64  ? 340 GLU A CA  1 
ATOM   6580 C C   . GLU E 5 8   ? -15.540 14.972  -17.826 1.00 51.62  ? 340 GLU A C   1 
ATOM   6581 O O   . GLU E 5 8   ? -15.656 14.069  -16.989 1.00 41.09  ? 340 GLU A O   1 
ATOM   6582 C CB  . GLU E 5 8   ? -17.313 16.747  -17.935 1.00 55.58  ? 340 GLU A CB  1 
ATOM   6583 C CG  . GLU E 5 8   ? -17.762 18.150  -17.561 1.00 73.04  ? 340 GLU A CG  1 
ATOM   6584 C CD  . GLU E 5 8   ? -19.237 18.387  -17.828 1.00 84.58  ? 340 GLU A CD  1 
ATOM   6585 O OE1 . GLU E 5 8   ? -19.708 19.520  -17.590 1.00 92.85  ? 340 GLU A OE1 1 
ATOM   6586 O OE2 . GLU E 5 8   ? -19.924 17.444  -18.275 1.00 81.18  ? 340 GLU A OE2 1 
ATOM   6587 N N   . VAL E 5 9   ? -15.101 14.739  -19.064 1.00 51.82  ? 341 VAL A N   1 
ATOM   6588 C CA  . VAL E 5 9   ? -14.821 13.372  -19.487 1.00 49.00  ? 341 VAL A CA  1 
ATOM   6589 C C   . VAL E 5 9   ? -13.420 12.929  -19.064 1.00 53.55  ? 341 VAL A C   1 
ATOM   6590 O O   . VAL E 5 9   ? -13.205 11.747  -18.775 1.00 57.89  ? 341 VAL A O   1 
ATOM   6591 C CB  . VAL E 5 9   ? -15.030 13.228  -21.006 1.00 34.04  ? 341 VAL A CB  1 
ATOM   6592 C CG1 . VAL E 5 9   ? -16.453 13.598  -21.366 1.00 35.58  ? 341 VAL A CG1 1 
ATOM   6593 C CG2 . VAL E 5 9   ? -14.047 14.088  -21.776 1.00 42.62  ? 341 VAL A CG2 1 
ATOM   6594 N N   . PHE E 5 10  ? -12.453 13.848  -19.024 1.00 42.34  ? 342 PHE A N   1 
ATOM   6595 C CA  . PHE E 5 10  ? -11.088 13.466  -18.671 1.00 39.77  ? 342 PHE A CA  1 
ATOM   6596 C C   . PHE E 5 10  ? -10.887 13.395  -17.161 1.00 52.17  ? 342 PHE A C   1 
ATOM   6597 O O   . PHE E 5 10  ? -10.212 12.485  -16.666 1.00 51.99  ? 342 PHE A O   1 
ATOM   6598 C CB  . PHE E 5 10  ? -10.091 14.443  -19.295 1.00 37.58  ? 342 PHE A CB  1 
ATOM   6599 C CG  . PHE E 5 10  ? -9.766  14.145  -20.732 1.00 42.42  ? 342 PHE A CG  1 
ATOM   6600 C CD1 . PHE E 5 10  ? -10.554 14.644  -21.755 1.00 46.44  ? 342 PHE A CD1 1 
ATOM   6601 C CD2 . PHE E 5 10  ? -8.669  13.365  -21.057 1.00 36.75  ? 342 PHE A CD2 1 
ATOM   6602 C CE1 . PHE E 5 10  ? -10.255 14.369  -23.077 1.00 44.38  ? 342 PHE A CE1 1 
ATOM   6603 C CE2 . PHE E 5 10  ? -8.363  13.088  -22.377 1.00 33.52  ? 342 PHE A CE2 1 
ATOM   6604 C CZ  . PHE E 5 10  ? -9.157  13.591  -23.388 1.00 38.44  ? 342 PHE A CZ  1 
ATOM   6605 N N   . ASN E 5 11  ? -11.472 14.331  -16.416 1.00 46.30  ? 343 ASN A N   1 
ATOM   6606 C CA  . ASN E 5 11  ? -11.313 14.409  -14.970 1.00 45.24  ? 343 ASN A CA  1 
ATOM   6607 C C   . ASN E 5 11  ? -12.342 13.578  -14.211 1.00 51.99  ? 343 ASN A C   1 
ATOM   6608 O O   . ASN E 5 11  ? -12.405 13.674  -12.981 1.00 57.05  ? 343 ASN A O   1 
ATOM   6609 C CB  . ASN E 5 11  ? -11.410 15.865  -14.502 1.00 65.27  ? 343 ASN A CB  1 
ATOM   6610 C CG  . ASN E 5 11  ? -10.102 16.626  -14.629 1.00 75.13  ? 343 ASN A CG  1 
ATOM   6611 O OD1 . ASN E 5 11  ? -9.824  17.513  -13.822 1.00 84.45  ? 343 ASN A OD1 1 
ATOM   6612 N ND2 . ASN E 5 11  ? -9.298  16.291  -15.638 1.00 68.37  ? 343 ASN A ND2 1 
ATOM   6613 N N   . ALA E 5 12  ? -13.152 12.785  -14.911 1.00 51.54  ? 344 ALA A N   1 
ATOM   6614 C CA  . ALA E 5 12  ? -14.251 12.072  -14.270 1.00 49.25  ? 344 ALA A CA  1 
ATOM   6615 C C   . ALA E 5 12  ? -13.744 11.154  -13.163 1.00 47.93  ? 344 ALA A C   1 
ATOM   6616 O O   . ALA E 5 12  ? -12.717 10.485  -13.305 1.00 43.10  ? 344 ALA A O   1 
ATOM   6617 C CB  . ALA E 5 12  ? -15.032 11.262  -15.306 1.00 49.60  ? 344 ALA A CB  1 
ATOM   6618 N N   . THR E 5 13  ? -14.474 11.139  -12.044 1.00 52.46  ? 345 THR A N   1 
ATOM   6619 C CA  . THR E 5 13  ? -14.069 10.324  -10.903 1.00 49.28  ? 345 THR A CA  1 
ATOM   6620 C C   . THR E 5 13  ? -14.134 8.838   -11.235 1.00 52.25  ? 345 THR A C   1 
ATOM   6621 O O   . THR E 5 13  ? -13.255 8.067   -10.833 1.00 53.37  ? 345 THR A O   1 
ATOM   6622 C CB  . THR E 5 13  ? -14.946 10.642  -9.693  1.00 47.05  ? 345 THR A CB  1 
ATOM   6623 O OG1 . THR E 5 13  ? -15.269 12.039  -9.692  1.00 56.13  ? 345 THR A OG1 1 
ATOM   6624 C CG2 . THR E 5 13  ? -14.213 10.304  -8.405  1.00 51.40  ? 345 THR A CG2 1 
ATOM   6625 N N   . ARG E 5 14  ? -15.166 8.420   -11.960 1.00 55.07  ? 346 ARG A N   1 
ATOM   6626 C CA  . ARG E 5 14  ? -15.329 7.034   -12.367 1.00 51.94  ? 346 ARG A CA  1 
ATOM   6627 C C   . ARG E 5 14  ? -15.614 6.976   -13.860 1.00 43.92  ? 346 ARG A C   1 
ATOM   6628 O O   . ARG E 5 14  ? -16.341 7.818   -14.396 1.00 43.78  ? 346 ARG A O   1 
ATOM   6629 C CB  . ARG E 5 14  ? -16.458 6.357   -11.578 1.00 51.56  ? 346 ARG A CB  1 
ATOM   6630 C CG  . ARG E 5 14  ? -15.979 5.293   -10.600 1.00 80.11  ? 346 ARG A CG  1 
ATOM   6631 C CD  . ARG E 5 14  ? -17.094 4.851   -9.663  1.00 89.71  ? 346 ARG A CD  1 
ATOM   6632 N NE  . ARG E 5 14  ? -18.386 4.784   -10.335 1.00 97.76  ? 346 ARG A NE  1 
ATOM   6633 C CZ  . ARG E 5 14  ? -18.786 3.773   -11.095 1.00 102.38 ? 346 ARG A CZ  1 
ATOM   6634 N NH1 . ARG E 5 14  ? -18.011 2.724   -11.316 1.00 97.39  ? 346 ARG A NH1 1 
ATOM   6635 N NH2 . ARG E 5 14  ? -19.994 3.817   -11.648 1.00 102.46 ? 346 ARG A NH2 1 
ATOM   6636 N N   . PHE E 5 15  ? -15.028 5.988   -14.528 1.00 46.85  ? 347 PHE A N   1 
ATOM   6637 C CA  . PHE E 5 15  ? -15.254 5.751   -15.945 1.00 44.07  ? 347 PHE A CA  1 
ATOM   6638 C C   . PHE E 5 15  ? -16.210 4.578   -16.134 1.00 43.79  ? 347 PHE A C   1 
ATOM   6639 O O   . PHE E 5 15  ? -16.523 3.836   -15.201 1.00 44.96  ? 347 PHE A O   1 
ATOM   6640 C CB  . PHE E 5 15  ? -13.932 5.480   -16.668 1.00 45.74  ? 347 PHE A CB  1 
ATOM   6641 C CG  . PHE E 5 15  ? -13.241 6.716   -17.172 1.00 47.97  ? 347 PHE A CG  1 
ATOM   6642 C CD1 . PHE E 5 15  ? -13.073 7.820   -16.354 1.00 48.82  ? 347 PHE A CD1 1 
ATOM   6643 C CD2 . PHE E 5 15  ? -12.741 6.763   -18.463 1.00 41.25  ? 347 PHE A CD2 1 
ATOM   6644 C CE1 . PHE E 5 15  ? -12.432 8.951   -16.820 1.00 41.17  ? 347 PHE A CE1 1 
ATOM   6645 C CE2 . PHE E 5 15  ? -12.097 7.891   -18.931 1.00 31.83  ? 347 PHE A CE2 1 
ATOM   6646 C CZ  . PHE E 5 15  ? -11.943 8.985   -18.109 1.00 29.87  ? 347 PHE A CZ  1 
ATOM   6647 N N   . ALA E 5 16  ? -16.673 4.416   -17.368 1.00 32.06  ? 348 ALA A N   1 
ATOM   6648 C CA  . ALA E 5 16  ? -17.598 3.348   -17.705 1.00 38.81  ? 348 ALA A CA  1 
ATOM   6649 C C   . ALA E 5 16  ? -16.843 2.088   -18.115 1.00 42.10  ? 348 ALA A C   1 
ATOM   6650 O O   . ALA E 5 16  ? -15.691 2.137   -18.553 1.00 41.40  ? 348 ALA A O   1 
ATOM   6651 C CB  . ALA E 5 16  ? -18.536 3.782   -18.832 1.00 39.79  ? 348 ALA A CB  1 
ATOM   6652 N N   . SER E 5 17  ? -17.510 0.948   -17.957 1.00 43.57  ? 349 SER A N   1 
ATOM   6653 C CA  . SER E 5 17  ? -16.993 -0.294  -18.512 1.00 39.48  ? 349 SER A CA  1 
ATOM   6654 C C   . SER E 5 17  ? -16.992 -0.216  -20.035 1.00 43.95  ? 349 SER A C   1 
ATOM   6655 O O   . SER E 5 17  ? -17.818 0.470   -20.644 1.00 39.60  ? 349 SER A O   1 
ATOM   6656 C CB  . SER E 5 17  ? -17.826 -1.485  -18.039 1.00 38.54  ? 349 SER A CB  1 
ATOM   6657 O OG  . SER E 5 17  ? -17.699 -1.669  -16.640 1.00 34.10  ? 349 SER A OG  1 
ATOM   6658 N N   . VAL E 5 18  ? -16.046 -0.929  -20.650 1.00 48.02  ? 350 VAL A N   1 
ATOM   6659 C CA  . VAL E 5 18  ? -15.818 -0.775  -22.085 1.00 36.78  ? 350 VAL A CA  1 
ATOM   6660 C C   . VAL E 5 18  ? -17.047 -1.201  -22.881 1.00 35.11  ? 350 VAL A C   1 
ATOM   6661 O O   . VAL E 5 18  ? -17.365 -0.607  -23.918 1.00 35.48  ? 350 VAL A O   1 
ATOM   6662 C CB  . VAL E 5 18  ? -14.553 -1.546  -22.515 1.00 24.44  ? 350 VAL A CB  1 
ATOM   6663 C CG1 . VAL E 5 18  ? -14.701 -3.029  -22.236 1.00 30.89  ? 350 VAL A CG1 1 
ATOM   6664 C CG2 . VAL E 5 18  ? -14.245 -1.297  -23.985 1.00 26.20  ? 350 VAL A CG2 1 
ATOM   6665 N N   . TYR E 5 19  ? -17.765 -2.227  -22.409 1.00 29.16  ? 351 TYR A N   1 
ATOM   6666 C CA  . TYR E 5 19  ? -18.969 -2.661  -23.109 1.00 31.52  ? 351 TYR A CA  1 
ATOM   6667 C C   . TYR E 5 19  ? -20.062 -1.601  -23.077 1.00 36.71  ? 351 TYR A C   1 
ATOM   6668 O O   . TYR E 5 19  ? -20.921 -1.585  -23.966 1.00 33.27  ? 351 TYR A O   1 
ATOM   6669 C CB  . TYR E 5 19  ? -19.492 -3.971  -22.510 1.00 29.84  ? 351 TYR A CB  1 
ATOM   6670 C CG  . TYR E 5 19  ? -20.435 -3.794  -21.338 1.00 42.11  ? 351 TYR A CG  1 
ATOM   6671 C CD1 . TYR E 5 19  ? -19.951 -3.508  -20.069 1.00 48.64  ? 351 TYR A CD1 1 
ATOM   6672 C CD2 . TYR E 5 19  ? -21.810 -3.929  -21.501 1.00 40.35  ? 351 TYR A CD2 1 
ATOM   6673 C CE1 . TYR E 5 19  ? -20.810 -3.350  -18.994 1.00 46.96  ? 351 TYR A CE1 1 
ATOM   6674 C CE2 . TYR E 5 19  ? -22.676 -3.773  -20.433 1.00 42.76  ? 351 TYR A CE2 1 
ATOM   6675 C CZ  . TYR E 5 19  ? -22.171 -3.484  -19.182 1.00 48.61  ? 351 TYR A CZ  1 
ATOM   6676 O OH  . TYR E 5 19  ? -23.032 -3.329  -18.118 1.00 41.79  ? 351 TYR A OH  1 
ATOM   6677 N N   . ALA E 5 20  ? -20.040 -0.713  -22.084 1.00 44.62  ? 352 ALA A N   1 
ATOM   6678 C CA  . ALA E 5 20  ? -21.023 0.358   -21.972 1.00 42.61  ? 352 ALA A CA  1 
ATOM   6679 C C   . ALA E 5 20  ? -20.327 1.711   -22.038 1.00 39.45  ? 352 ALA A C   1 
ATOM   6680 O O   . ALA E 5 20  ? -20.576 2.588   -21.205 1.00 49.70  ? 352 ALA A O   1 
ATOM   6681 C CB  . ALA E 5 20  ? -21.822 0.225   -20.674 1.00 31.77  ? 352 ALA A CB  1 
ATOM   6682 N N   . TRP E 5 21  ? -19.441 1.875   -23.020 1.00 36.57  ? 353 TRP A N   1 
ATOM   6683 C CA  . TRP E 5 21  ? -18.621 3.075   -23.121 1.00 41.71  ? 353 TRP A CA  1 
ATOM   6684 C C   . TRP E 5 21  ? -19.477 4.331   -23.235 1.00 38.40  ? 353 TRP A C   1 
ATOM   6685 O O   . TRP E 5 21  ? -20.469 4.367   -23.968 1.00 44.07  ? 353 TRP A O   1 
ATOM   6686 C CB  . TRP E 5 21  ? -17.683 2.968   -24.326 1.00 45.84  ? 353 TRP A CB  1 
ATOM   6687 C CG  . TRP E 5 21  ? -18.364 2.532   -25.595 1.00 37.04  ? 353 TRP A CG  1 
ATOM   6688 C CD1 . TRP E 5 21  ? -18.612 1.250   -25.992 1.00 37.01  ? 353 TRP A CD1 1 
ATOM   6689 C CD2 . TRP E 5 21  ? -18.873 3.378   -26.635 1.00 31.01  ? 353 TRP A CD2 1 
ATOM   6690 N NE1 . TRP E 5 21  ? -19.247 1.244   -27.210 1.00 33.97  ? 353 TRP A NE1 1 
ATOM   6691 C CE2 . TRP E 5 21  ? -19.419 2.538   -27.626 1.00 30.45  ? 353 TRP A CE2 1 
ATOM   6692 C CE3 . TRP E 5 21  ? -18.921 4.762   -26.822 1.00 34.85  ? 353 TRP A CE3 1 
ATOM   6693 C CZ2 . TRP E 5 21  ? -20.006 3.036   -28.787 1.00 32.80  ? 353 TRP A CZ2 1 
ATOM   6694 C CZ3 . TRP E 5 21  ? -19.505 5.255   -27.976 1.00 36.09  ? 353 TRP A CZ3 1 
ATOM   6695 C CH2 . TRP E 5 21  ? -20.040 4.394   -28.943 1.00 35.47  ? 353 TRP A CH2 1 
ATOM   6696 N N   . ASN E 5 22  ? -19.084 5.365   -22.494 1.00 37.16  ? 354 ASN A N   1 
ATOM   6697 C CA  . ASN E 5 22  ? -19.766 6.650   -22.544 1.00 40.29  ? 354 ASN A CA  1 
ATOM   6698 C C   . ASN E 5 22  ? -19.358 7.429   -23.787 1.00 30.89  ? 354 ASN A C   1 
ATOM   6699 O O   . ASN E 5 22  ? -18.206 7.374   -24.222 1.00 36.40  ? 354 ASN A O   1 
ATOM   6700 C CB  . ASN E 5 22  ? -19.451 7.476   -21.296 1.00 28.49  ? 354 ASN A CB  1 
ATOM   6701 C CG  . ASN E 5 22  ? -20.339 7.121   -20.119 1.00 42.26  ? 354 ASN A CG  1 
ATOM   6702 O OD1 . ASN E 5 22  ? -21.498 6.745   -20.293 1.00 57.67  ? 354 ASN A OD1 1 
ATOM   6703 N ND2 . ASN E 5 22  ? -19.799 7.247   -18.911 1.00 49.31  ? 354 ASN A ND2 1 
ATOM   6704 N N   . ARG E 5 23  ? -20.316 8.154   -24.358 1.00 32.73  ? 355 ARG A N   1 
ATOM   6705 C CA  . ARG E 5 23  ? -20.064 9.069   -25.463 1.00 29.49  ? 355 ARG A CA  1 
ATOM   6706 C C   . ARG E 5 23  ? -20.578 10.442  -25.065 1.00 42.18  ? 355 ARG A C   1 
ATOM   6707 O O   . ARG E 5 23  ? -21.756 10.589  -24.723 1.00 46.15  ? 355 ARG A O   1 
ATOM   6708 C CB  . ARG E 5 23  ? -20.740 8.594   -26.752 1.00 33.64  ? 355 ARG A CB  1 
ATOM   6709 C CG  . ARG E 5 23  ? -20.972 9.704   -27.767 1.00 41.07  ? 355 ARG A CG  1 
ATOM   6710 C CD  . ARG E 5 23  ? -21.157 9.150   -29.167 1.00 31.26  ? 355 ARG A CD  1 
ATOM   6711 N NE  . ARG E 5 23  ? -19.918 8.586   -29.689 1.00 39.77  ? 355 ARG A NE  1 
ATOM   6712 C CZ  . ARG E 5 23  ? -19.765 8.128   -30.923 1.00 45.55  ? 355 ARG A CZ  1 
ATOM   6713 N NH1 . ARG E 5 23  ? -20.758 8.151   -31.797 1.00 36.69  ? 355 ARG A NH1 1 
ATOM   6714 N NH2 . ARG E 5 23  ? -18.585 7.635   -31.291 1.00 43.73  ? 355 ARG A NH2 1 
ATOM   6715 N N   . LYS E 5 24  ? -19.701 11.441  -25.107 1.00 34.76  ? 356 LYS A N   1 
ATOM   6716 C CA  . LYS E 5 24  ? -20.055 12.806  -24.737 1.00 31.20  ? 356 LYS A CA  1 
ATOM   6717 C C   . LYS E 5 24  ? -20.138 13.648  -26.002 1.00 39.69  ? 356 LYS A C   1 
ATOM   6718 O O   . LYS E 5 24  ? -19.127 13.875  -26.675 1.00 41.90  ? 356 LYS A O   1 
ATOM   6719 C CB  . LYS E 5 24  ? -19.046 13.392  -23.753 1.00 32.31  ? 356 LYS A CB  1 
ATOM   6720 C CG  . LYS E 5 24  ? -19.464 14.738  -23.180 1.00 39.04  ? 356 LYS A CG  1 
ATOM   6721 C CD  . LYS E 5 24  ? -20.944 14.739  -22.819 1.00 48.43  ? 356 LYS A CD  1 
ATOM   6722 C CE  . LYS E 5 24  ? -21.270 15.804  -21.788 1.00 50.52  ? 356 LYS A CE  1 
ATOM   6723 N NZ  . LYS E 5 24  ? -20.651 15.489  -20.471 1.00 68.69  ? 356 LYS A NZ  1 
ATOM   6724 N N   . ARG E 5 25  ? -21.345 14.104  -26.321 1.00 56.49  ? 357 ARG A N   1 
ATOM   6725 C CA  . ARG E 5 25  ? -21.548 15.009  -27.440 1.00 50.15  ? 357 ARG A CA  1 
ATOM   6726 C C   . ARG E 5 25  ? -21.086 16.408  -27.050 1.00 52.29  ? 357 ARG A C   1 
ATOM   6727 O O   . ARG E 5 25  ? -21.462 16.923  -25.992 1.00 56.07  ? 357 ARG A O   1 
ATOM   6728 C CB  . ARG E 5 25  ? -23.019 15.016  -27.849 1.00 36.78  ? 357 ARG A CB  1 
ATOM   6729 C CG  . ARG E 5 25  ? -23.302 15.703  -29.169 1.00 43.86  ? 357 ARG A CG  1 
ATOM   6730 C CD  . ARG E 5 25  ? -24.747 15.494  -29.583 1.00 42.94  ? 357 ARG A CD  1 
ATOM   6731 N NE  . ARG E 5 25  ? -25.070 16.208  -30.811 1.00 54.59  ? 357 ARG A NE  1 
ATOM   6732 C CZ  . ARG E 5 25  ? -25.500 17.461  -30.856 1.00 60.40  ? 357 ARG A CZ  1 
ATOM   6733 N NH1 . ARG E 5 25  ? -25.668 18.174  -29.753 1.00 47.63  ? 357 ARG A NH1 1 
ATOM   6734 N NH2 . ARG E 5 25  ? -25.770 18.013  -32.035 1.00 68.02  ? 357 ARG A NH2 1 
ATOM   6735 N N   . ILE E 5 26  ? -20.265 17.017  -27.901 1.00 51.14  ? 358 ILE A N   1 
ATOM   6736 C CA  . ILE E 5 26  ? -19.662 18.317  -27.631 1.00 50.16  ? 358 ILE A CA  1 
ATOM   6737 C C   . ILE E 5 26  ? -19.949 19.234  -28.811 1.00 59.59  ? 358 ILE A C   1 
ATOM   6738 O O   . ILE E 5 26  ? -19.649 18.887  -29.959 1.00 50.74  ? 358 ILE A O   1 
ATOM   6739 C CB  . ILE E 5 26  ? -18.147 18.193  -27.378 1.00 36.23  ? 358 ILE A CB  1 
ATOM   6740 C CG1 . ILE E 5 26  ? -17.899 17.671  -25.960 1.00 41.28  ? 358 ILE A CG1 1 
ATOM   6741 C CG2 . ILE E 5 26  ? -17.444 19.520  -27.615 1.00 46.43  ? 358 ILE A CG2 1 
ATOM   6742 C CD1 . ILE E 5 26  ? -16.599 16.926  -25.794 1.00 53.98  ? 358 ILE A CD1 1 
ATOM   6743 N N   . SER E 5 27  ? -20.532 20.398  -28.528 1.00 74.59  ? 359 SER A N   1 
ATOM   6744 C CA  . SER E 5 27  ? -20.956 21.315  -29.577 1.00 73.80  ? 359 SER A CA  1 
ATOM   6745 C C   . SER E 5 27  ? -21.049 22.724  -29.012 1.00 68.54  ? 359 SER A C   1 
ATOM   6746 O O   . SER E 5 27  ? -20.949 22.941  -27.801 1.00 55.52  ? 359 SER A O   1 
ATOM   6747 C CB  . SER E 5 27  ? -22.299 20.892  -30.178 1.00 55.82  ? 359 SER A CB  1 
ATOM   6748 O OG  . SER E 5 27  ? -23.306 20.844  -29.184 1.00 49.39  ? 359 SER A OG  1 
ATOM   6749 N N   . ASN E 5 28  ? -21.253 23.678  -29.927 1.00 79.45  ? 360 ASN A N   1 
ATOM   6750 C CA  . ASN E 5 28  ? -21.438 25.109  -29.671 1.00 75.56  ? 360 ASN A CA  1 
ATOM   6751 C C   . ASN E 5 28  ? -20.604 25.593  -28.489 1.00 69.60  ? 360 ASN A C   1 
ATOM   6752 O O   . ASN E 5 28  ? -21.137 26.115  -27.505 1.00 70.57  ? 360 ASN A O   1 
ATOM   6753 C CB  . ASN E 5 28  ? -22.930 25.512  -29.544 1.00 61.18  ? 360 ASN A CB  1 
ATOM   6754 C CG  . ASN E 5 28  ? -23.801 24.560  -28.700 1.00 80.17  ? 360 ASN A CG  1 
ATOM   6755 O OD1 . ASN E 5 28  ? -23.635 23.345  -28.693 1.00 88.78  ? 360 ASN A OD1 1 
ATOM   6756 N ND2 . ASN E 5 28  ? -24.799 25.142  -28.035 1.00 83.72  ? 360 ASN A ND2 1 
ATOM   6757 N N   . CYS E 5 29  ? -19.286 25.412  -28.589 1.00 64.12  ? 361 CYS A N   1 
ATOM   6758 C CA  . CYS E 5 29  ? -18.365 25.784  -27.527 1.00 68.74  ? 361 CYS A CA  1 
ATOM   6759 C C   . CYS E 5 29  ? -16.998 26.069  -28.133 1.00 73.63  ? 361 CYS A C   1 
ATOM   6760 O O   . CYS E 5 29  ? -16.721 25.735  -29.289 1.00 65.38  ? 361 CYS A O   1 
ATOM   6761 C CB  . CYS E 5 29  ? -18.274 24.685  -26.465 1.00 68.84  ? 361 CYS A CB  1 
ATOM   6762 S SG  . CYS E 5 29  ? -17.825 23.050  -27.107 1.00 72.49  ? 361 CYS A SG  1 
ATOM   6763 N N   . VAL E 5 30  ? -16.143 26.696  -27.335 1.00 76.48  ? 362 VAL A N   1 
ATOM   6764 C CA  . VAL E 5 30  ? -14.772 26.991  -27.731 1.00 67.40  ? 362 VAL A CA  1 
ATOM   6765 C C   . VAL E 5 30  ? -13.876 25.867  -27.232 1.00 68.73  ? 362 VAL A C   1 
ATOM   6766 O O   . VAL E 5 30  ? -13.921 25.501  -26.051 1.00 74.16  ? 362 VAL A O   1 
ATOM   6767 C CB  . VAL E 5 30  ? -14.318 28.351  -27.178 1.00 82.11  ? 362 VAL A CB  1 
ATOM   6768 C CG1 . VAL E 5 30  ? -12.904 28.663  -27.639 1.00 76.23  ? 362 VAL A CG1 1 
ATOM   6769 C CG2 . VAL E 5 30  ? -15.283 29.446  -27.609 1.00 85.62  ? 362 VAL A CG2 1 
ATOM   6770 N N   . ALA E 5 31  ? -13.065 25.314  -28.128 1.00 75.83  ? 363 ALA A N   1 
ATOM   6771 C CA  . ALA E 5 31  ? -12.261 24.128  -27.845 1.00 84.13  ? 363 ALA A CA  1 
ATOM   6772 C C   . ALA E 5 31  ? -10.797 24.530  -27.698 1.00 83.79  ? 363 ALA A C   1 
ATOM   6773 O O   . ALA E 5 31  ? -10.101 24.753  -28.693 1.00 89.16  ? 363 ALA A O   1 
ATOM   6774 C CB  . ALA E 5 31  ? -12.441 23.084  -28.942 1.00 76.86  ? 363 ALA A CB  1 
ATOM   6775 N N   . ASP E 5 32  ? -10.332 24.614  -26.452 1.00 79.50  ? 364 ASP A N   1 
ATOM   6776 C CA  . ASP E 5 32  ? -8.913  24.804  -26.157 1.00 85.92  ? 364 ASP A CA  1 
ATOM   6777 C C   . ASP E 5 32  ? -8.279  23.421  -26.096 1.00 81.16  ? 364 ASP A C   1 
ATOM   6778 O O   . ASP E 5 32  ? -8.231  22.780  -25.045 1.00 83.54  ? 364 ASP A O   1 
ATOM   6779 C CB  . ASP E 5 32  ? -8.722  25.572  -24.855 1.00 86.25  ? 364 ASP A CB  1 
ATOM   6780 C CG  . ASP E 5 32  ? -7.258  25.796  -24.518 1.00 92.37  ? 364 ASP A CG  1 
ATOM   6781 O OD1 . ASP E 5 32  ? -6.416  25.734  -25.439 1.00 92.90  ? 364 ASP A OD1 1 
ATOM   6782 O OD2 . ASP E 5 32  ? -6.948  26.028  -23.330 1.00 91.57  ? 364 ASP A OD2 1 
ATOM   6783 N N   . TYR E 5 33  ? -7.790  22.948  -27.243 1.00 68.70  ? 365 TYR A N   1 
ATOM   6784 C CA  . TYR E 5 33  ? -7.187  21.623  -27.298 1.00 67.85  ? 365 TYR A CA  1 
ATOM   6785 C C   . TYR E 5 33  ? -5.823  21.564  -26.625 1.00 72.77  ? 365 TYR A C   1 
ATOM   6786 O O   . TYR E 5 33  ? -5.320  20.461  -26.385 1.00 73.69  ? 365 TYR A O   1 
ATOM   6787 C CB  . TYR E 5 33  ? -7.067  21.160  -28.751 1.00 59.42  ? 365 TYR A CB  1 
ATOM   6788 C CG  . TYR E 5 33  ? -8.397  20.981  -29.448 1.00 66.12  ? 365 TYR A CG  1 
ATOM   6789 C CD1 . TYR E 5 33  ? -9.288  19.998  -29.040 1.00 64.39  ? 365 TYR A CD1 1 
ATOM   6790 C CD2 . TYR E 5 33  ? -8.756  21.786  -30.522 1.00 71.37  ? 365 TYR A CD2 1 
ATOM   6791 C CE1 . TYR E 5 33  ? -10.505 19.827  -29.675 1.00 62.64  ? 365 TYR A CE1 1 
ATOM   6792 C CE2 . TYR E 5 33  ? -9.972  21.622  -31.164 1.00 73.59  ? 365 TYR A CE2 1 
ATOM   6793 C CZ  . TYR E 5 33  ? -10.841 20.639  -30.737 1.00 62.76  ? 365 TYR A CZ  1 
ATOM   6794 O OH  . TYR E 5 33  ? -12.052 20.469  -31.370 1.00 55.86  ? 365 TYR A OH  1 
ATOM   6795 N N   . SER E 5 34  ? -5.219  22.712  -26.308 1.00 73.98  ? 366 SER A N   1 
ATOM   6796 C CA  . SER E 5 34  ? -3.886  22.719  -25.717 1.00 62.02  ? 366 SER A CA  1 
ATOM   6797 C C   . SER E 5 34  ? -3.870  22.177  -24.296 1.00 68.80  ? 366 SER A C   1 
ATOM   6798 O O   . SER E 5 34  ? -2.821  21.714  -23.837 1.00 76.41  ? 366 SER A O   1 
ATOM   6799 C CB  . SER E 5 34  ? -3.305  24.133  -25.746 1.00 65.36  ? 366 SER A CB  1 
ATOM   6800 O OG  . SER E 5 34  ? -4.249  25.083  -25.285 1.00 91.61  ? 366 SER A OG  1 
ATOM   6801 N N   . VAL E 5 35  ? -5.001  22.221  -23.588 1.00 68.42  ? 367 VAL A N   1 
ATOM   6802 C CA  . VAL E 5 35  ? -5.054  21.621  -22.260 1.00 71.08  ? 367 VAL A CA  1 
ATOM   6803 C C   . VAL E 5 35  ? -4.798  20.123  -22.345 1.00 69.28  ? 367 VAL A C   1 
ATOM   6804 O O   . VAL E 5 35  ? -4.318  19.509  -21.385 1.00 62.62  ? 367 VAL A O   1 
ATOM   6805 C CB  . VAL E 5 35  ? -6.407  21.935  -21.585 1.00 78.79  ? 367 VAL A CB  1 
ATOM   6806 C CG1 . VAL E 5 35  ? -7.552  21.271  -22.336 1.00 67.46  ? 367 VAL A CG1 1 
ATOM   6807 C CG2 . VAL E 5 35  ? -6.393  21.504  -20.124 1.00 69.05  ? 367 VAL A CG2 1 
ATOM   6808 N N   . LEU E 5 36  ? -5.094  19.514  -23.493 1.00 71.24  ? 368 LEU A N   1 
ATOM   6809 C CA  . LEU E 5 36  ? -4.908  18.077  -23.653 1.00 60.83  ? 368 LEU A CA  1 
ATOM   6810 C C   . LEU E 5 36  ? -3.470  17.735  -24.025 1.00 60.15  ? 368 LEU A C   1 
ATOM   6811 O O   . LEU E 5 36  ? -2.783  17.011  -23.295 1.00 62.19  ? 368 LEU A O   1 
ATOM   6812 C CB  . LEU E 5 36  ? -5.882  17.545  -24.707 1.00 49.68  ? 368 LEU A CB  1 
ATOM   6813 C CG  . LEU E 5 36  ? -7.353  17.740  -24.346 1.00 59.65  ? 368 LEU A CG  1 
ATOM   6814 C CD1 . LEU E 5 36  ? -8.245  17.537  -25.559 1.00 49.30  ? 368 LEU A CD1 1 
ATOM   6815 C CD2 . LEU E 5 36  ? -7.728  16.781  -23.236 1.00 55.51  ? 368 LEU A CD2 1 
ATOM   6816 N N   . TYR E 5 37  ? -2.992  18.248  -25.161 1.00 58.37  ? 369 TYR A N   1 
ATOM   6817 C CA  . TYR E 5 37  ? -1.704  17.795  -25.672 1.00 66.53  ? 369 TYR A CA  1 
ATOM   6818 C C   . TYR E 5 37  ? -0.516  18.357  -24.901 1.00 73.01  ? 369 TYR A C   1 
ATOM   6819 O O   . TYR E 5 37  ? 0.551   17.734  -24.906 1.00 64.75  ? 369 TYR A O   1 
ATOM   6820 C CB  . TYR E 5 37  ? -1.567  18.112  -27.168 1.00 59.42  ? 369 TYR A CB  1 
ATOM   6821 C CG  . TYR E 5 37  ? -1.689  19.561  -27.599 1.00 65.52  ? 369 TYR A CG  1 
ATOM   6822 C CD1 . TYR E 5 37  ? -0.667  20.473  -27.364 1.00 62.31  ? 369 TYR A CD1 1 
ATOM   6823 C CD2 . TYR E 5 37  ? -2.804  20.000  -28.303 1.00 59.93  ? 369 TYR A CD2 1 
ATOM   6824 C CE1 . TYR E 5 37  ? -0.771  21.790  -27.780 1.00 63.83  ? 369 TYR A CE1 1 
ATOM   6825 C CE2 . TYR E 5 37  ? -2.915  21.311  -28.726 1.00 65.70  ? 369 TYR A CE2 1 
ATOM   6826 C CZ  . TYR E 5 37  ? -1.896  22.202  -28.461 1.00 68.68  ? 369 TYR A CZ  1 
ATOM   6827 O OH  . TYR E 5 37  ? -2.006  23.508  -28.879 1.00 76.96  ? 369 TYR A OH  1 
ATOM   6828 N N   . ASN E 5 38  ? -0.668  19.497  -24.231 1.00 73.35  ? 370 ASN A N   1 
ATOM   6829 C CA  . ASN E 5 38  ? 0.418   20.040  -23.424 1.00 72.74  ? 370 ASN A CA  1 
ATOM   6830 C C   . ASN E 5 38  ? 0.529   19.378  -22.055 1.00 73.91  ? 370 ASN A C   1 
ATOM   6831 O O   . ASN E 5 38  ? 1.258   19.886  -21.197 1.00 83.22  ? 370 ASN A O   1 
ATOM   6832 C CB  . ASN E 5 38  ? 0.253   21.553  -23.255 1.00 67.01  ? 370 ASN A CB  1 
ATOM   6833 C CG  . ASN E 5 38  ? 0.838   22.335  -24.415 1.00 57.98  ? 370 ASN A CG  1 
ATOM   6834 O OD1 . ASN E 5 38  ? 1.899   21.992  -24.936 1.00 63.68  ? 370 ASN A OD1 1 
ATOM   6835 N ND2 . ASN E 5 38  ? 0.148   23.393  -24.824 1.00 46.81  ? 370 ASN A ND2 1 
ATOM   6836 N N   . SER E 5 39  ? -0.173  18.272  -21.831 1.00 59.53  ? 371 SER A N   1 
ATOM   6837 C CA  . SER E 5 39  ? -0.078  17.532  -20.584 1.00 73.93  ? 371 SER A CA  1 
ATOM   6838 C C   . SER E 5 39  ? 1.033   16.487  -20.669 1.00 84.76  ? 371 SER A C   1 
ATOM   6839 O O   . SER E 5 39  ? 1.616   16.242  -21.727 1.00 77.31  ? 371 SER A O   1 
ATOM   6840 C CB  . SER E 5 39  ? -1.415  16.871  -20.249 1.00 62.35  ? 371 SER A CB  1 
ATOM   6841 O OG  . SER E 5 39  ? -1.355  16.196  -19.004 1.00 67.14  ? 371 SER A OG  1 
ATOM   6842 N N   . ALA E 5 40  ? 1.326   15.865  -19.524 1.00 81.11  ? 372 ALA A N   1 
ATOM   6843 C CA  . ALA E 5 40  ? 2.360   14.842  -19.445 1.00 68.57  ? 372 ALA A CA  1 
ATOM   6844 C C   . ALA E 5 40  ? 1.899   13.596  -18.698 1.00 67.65  ? 372 ALA A C   1 
ATOM   6845 O O   . ALA E 5 40  ? 2.730   12.739  -18.376 1.00 82.75  ? 372 ALA A O   1 
ATOM   6846 C CB  . ALA E 5 40  ? 3.624   15.402  -18.782 1.00 61.47  ? 372 ALA A CB  1 
ATOM   6847 N N   . SER E 5 41  ? 0.606   13.471  -18.415 1.00 63.79  ? 373 SER A N   1 
ATOM   6848 C CA  . SER E 5 41  ? 0.074   12.320  -17.699 1.00 75.03  ? 373 SER A CA  1 
ATOM   6849 C C   . SER E 5 41  ? -0.319  11.173  -18.622 1.00 74.24  ? 373 SER A C   1 
ATOM   6850 O O   . SER E 5 41  ? -0.743  10.122  -18.132 1.00 68.42  ? 373 SER A O   1 
ATOM   6851 C CB  . SER E 5 41  ? -1.135  12.739  -16.856 1.00 83.52  ? 373 SER A CB  1 
ATOM   6852 O OG  . SER E 5 41  ? -2.113  13.382  -17.655 1.00 79.71  ? 373 SER A OG  1 
ATOM   6853 N N   . PHE E 5 42  ? -0.183  11.343  -19.934 1.00 65.24  ? 374 PHE A N   1 
ATOM   6854 C CA  . PHE E 5 42  ? -0.611  10.337  -20.895 1.00 47.48  ? 374 PHE A CA  1 
ATOM   6855 C C   . PHE E 5 42  ? 0.536   9.400   -21.250 1.00 53.44  ? 374 PHE A C   1 
ATOM   6856 O O   . PHE E 5 42  ? 1.671   9.838   -21.460 1.00 57.74  ? 374 PHE A O   1 
ATOM   6857 C CB  . PHE E 5 42  ? -1.139  11.001  -22.168 1.00 42.75  ? 374 PHE A CB  1 
ATOM   6858 C CG  . PHE E 5 42  ? -2.257  11.973  -21.927 1.00 54.79  ? 374 PHE A CG  1 
ATOM   6859 C CD1 . PHE E 5 42  ? -3.237  11.706  -20.986 1.00 63.41  ? 374 PHE A CD1 1 
ATOM   6860 C CD2 . PHE E 5 42  ? -2.325  13.158  -22.641 1.00 50.78  ? 374 PHE A CD2 1 
ATOM   6861 C CE1 . PHE E 5 42  ? -4.267  12.601  -20.764 1.00 51.10  ? 374 PHE A CE1 1 
ATOM   6862 C CE2 . PHE E 5 42  ? -3.352  14.056  -22.423 1.00 38.70  ? 374 PHE A CE2 1 
ATOM   6863 C CZ  . PHE E 5 42  ? -4.323  13.779  -21.483 1.00 32.49  ? 374 PHE A CZ  1 
ATOM   6864 N N   . SER E 5 43  ? 0.232   8.104   -21.316 1.00 51.57  ? 375 SER A N   1 
ATOM   6865 C CA  . SER E 5 43  ? 1.180   7.123   -21.825 1.00 49.79  ? 375 SER A CA  1 
ATOM   6866 C C   . SER E 5 43  ? 0.963   6.799   -23.295 1.00 44.51  ? 375 SER A C   1 
ATOM   6867 O O   . SER E 5 43  ? 1.846   6.199   -23.919 1.00 49.65  ? 375 SER A O   1 
ATOM   6868 C CB  . SER E 5 43  ? 1.098   5.825   -21.013 1.00 58.12  ? 375 SER A CB  1 
ATOM   6869 O OG  . SER E 5 43  ? -0.165  5.204   -21.178 1.00 46.25  ? 375 SER A OG  1 
ATOM   6870 N N   . THR E 5 44  ? -0.184  7.177   -23.855 1.00 45.03  ? 376 THR A N   1 
ATOM   6871 C CA  . THR E 5 44  ? -0.491  6.922   -25.258 1.00 48.23  ? 376 THR A CA  1 
ATOM   6872 C C   . THR E 5 44  ? -1.389  8.040   -25.764 1.00 46.67  ? 376 THR A C   1 
ATOM   6873 O O   . THR E 5 44  ? -2.474  8.257   -25.217 1.00 45.66  ? 376 THR A O   1 
ATOM   6874 C CB  . THR E 5 44  ? -1.171  5.562   -25.441 1.00 44.15  ? 376 THR A CB  1 
ATOM   6875 O OG1 . THR E 5 44  ? -0.210  4.512   -25.271 1.00 60.78  ? 376 THR A OG1 1 
ATOM   6876 C CG2 . THR E 5 44  ? -1.798  5.455   -26.826 1.00 37.25  ? 376 THR A CG2 1 
ATOM   6877 N N   . PHE E 5 45  ? -0.934  8.750   -26.800 1.00 39.14  ? 377 PHE A N   1 
ATOM   6878 C CA  . PHE E 5 45  ? -1.704  9.827   -27.431 1.00 28.40  ? 377 PHE A CA  1 
ATOM   6879 C C   . PHE E 5 45  ? -1.520  9.651   -28.938 1.00 38.14  ? 377 PHE A C   1 
ATOM   6880 O O   . PHE E 5 45  ? -0.631  10.256  -29.543 1.00 51.56  ? 377 PHE A O   1 
ATOM   6881 C CB  . PHE E 5 45  ? -1.229  11.192  -26.944 1.00 39.37  ? 377 PHE A CB  1 
ATOM   6882 C CG  . PHE E 5 45  ? -2.206  12.314  -27.182 1.00 42.35  ? 377 PHE A CG  1 
ATOM   6883 C CD1 . PHE E 5 45  ? -2.941  12.392  -28.354 1.00 43.25  ? 377 PHE A CD1 1 
ATOM   6884 C CD2 . PHE E 5 45  ? -2.382  13.301  -26.225 1.00 40.33  ? 377 PHE A CD2 1 
ATOM   6885 C CE1 . PHE E 5 45  ? -3.832  13.428  -28.565 1.00 39.61  ? 377 PHE A CE1 1 
ATOM   6886 C CE2 . PHE E 5 45  ? -3.272  14.338  -26.430 1.00 41.44  ? 377 PHE A CE2 1 
ATOM   6887 C CZ  . PHE E 5 45  ? -3.996  14.402  -27.602 1.00 35.32  ? 377 PHE A CZ  1 
ATOM   6888 N N   . LYS E 5 46  ? -2.387  8.841   -29.541 1.00 46.40  ? 378 LYS A N   1 
ATOM   6889 C CA  . LYS E 5 46  ? -2.241  8.409   -30.925 1.00 39.79  ? 378 LYS A CA  1 
ATOM   6890 C C   . LYS E 5 46  ? -3.343  9.043   -31.764 1.00 39.47  ? 378 LYS A C   1 
ATOM   6891 O O   . LYS E 5 46  ? -4.529  8.789   -31.528 1.00 37.60  ? 378 LYS A O   1 
ATOM   6892 C CB  . LYS E 5 46  ? -2.294  6.884   -31.016 1.00 35.18  ? 378 LYS A CB  1 
ATOM   6893 C CG  . LYS E 5 46  ? -1.420  6.279   -32.099 1.00 44.47  ? 378 LYS A CG  1 
ATOM   6894 C CD  . LYS E 5 46  ? -1.298  4.772   -31.914 1.00 45.89  ? 378 LYS A CD  1 
ATOM   6895 C CE  . LYS E 5 46  ? -0.408  4.148   -32.977 1.00 41.13  ? 378 LYS A CE  1 
ATOM   6896 N NZ  . LYS E 5 46  ? -0.258  2.680   -32.785 1.00 35.84  ? 378 LYS A NZ  1 
ATOM   6897 N N   . CYS E 5 47  ? -2.950  9.849   -32.746 1.00 41.38  ? 379 CYS A N   1 
ATOM   6898 C CA  . CYS E 5 47  ? -3.882  10.586  -33.588 1.00 37.11  ? 379 CYS A CA  1 
ATOM   6899 C C   . CYS E 5 47  ? -3.849  10.047  -35.011 1.00 37.83  ? 379 CYS A C   1 
ATOM   6900 O O   . CYS E 5 47  ? -2.792  9.651   -35.513 1.00 41.35  ? 379 CYS A O   1 
ATOM   6901 C CB  . CYS E 5 47  ? -3.554  12.082  -33.593 1.00 44.98  ? 379 CYS A CB  1 
ATOM   6902 S SG  . CYS E 5 47  ? -3.758  12.912  -32.000 1.00 72.98  ? 379 CYS A SG  1 
ATOM   6903 N N   . TYR E 5 48  ? -5.013  10.040  -35.659 1.00 35.19  ? 380 TYR A N   1 
ATOM   6904 C CA  . TYR E 5 48  ? -5.162  9.532   -37.019 1.00 28.44  ? 380 TYR A CA  1 
ATOM   6905 C C   . TYR E 5 48  ? -5.872  10.586  -37.858 1.00 30.81  ? 380 TYR A C   1 
ATOM   6906 O O   . TYR E 5 48  ? -7.054  10.866  -37.636 1.00 36.55  ? 380 TYR A O   1 
ATOM   6907 C CB  . TYR E 5 48  ? -5.945  8.218   -37.037 1.00 27.16  ? 380 TYR A CB  1 
ATOM   6908 C CG  . TYR E 5 48  ? -5.361  7.119   -36.175 1.00 22.43  ? 380 TYR A CG  1 
ATOM   6909 C CD1 . TYR E 5 48  ? -5.665  7.033   -34.822 1.00 27.21  ? 380 TYR A CD1 1 
ATOM   6910 C CD2 . TYR E 5 48  ? -4.517  6.160   -36.717 1.00 22.68  ? 380 TYR A CD2 1 
ATOM   6911 C CE1 . TYR E 5 48  ? -5.136  6.028   -34.033 1.00 36.64  ? 380 TYR A CE1 1 
ATOM   6912 C CE2 . TYR E 5 48  ? -3.984  5.153   -35.937 1.00 30.71  ? 380 TYR A CE2 1 
ATOM   6913 C CZ  . TYR E 5 48  ? -4.296  5.090   -34.597 1.00 35.99  ? 380 TYR A CZ  1 
ATOM   6914 O OH  . TYR E 5 48  ? -3.768  4.085   -33.822 1.00 34.40  ? 380 TYR A OH  1 
ATOM   6915 N N   . GLY E 5 49  ? -5.153  11.176  -38.811 1.00 31.94  ? 381 GLY A N   1 
ATOM   6916 C CA  . GLY E 5 49  ? -5.756  12.050  -39.796 1.00 23.04  ? 381 GLY A CA  1 
ATOM   6917 C C   . GLY E 5 49  ? -6.020  13.471  -39.348 1.00 39.38  ? 381 GLY A C   1 
ATOM   6918 O O   . GLY E 5 49  ? -6.528  14.266  -40.149 1.00 40.90  ? 381 GLY A O   1 
ATOM   6919 N N   . VAL E 5 50  ? -5.706  13.819  -38.103 1.00 47.64  ? 382 VAL A N   1 
ATOM   6920 C CA  . VAL E 5 50  ? -5.894  15.175  -37.597 1.00 32.42  ? 382 VAL A CA  1 
ATOM   6921 C C   . VAL E 5 50  ? -4.682  15.557  -36.760 1.00 47.10  ? 382 VAL A C   1 
ATOM   6922 O O   . VAL E 5 50  ? -4.109  14.720  -36.054 1.00 60.63  ? 382 VAL A O   1 
ATOM   6923 C CB  . VAL E 5 50  ? -7.190  15.316  -36.769 1.00 32.02  ? 382 VAL A CB  1 
ATOM   6924 C CG1 . VAL E 5 50  ? -8.419  15.191  -37.661 1.00 49.87  ? 382 VAL A CG1 1 
ATOM   6925 C CG2 . VAL E 5 50  ? -7.226  14.289  -35.646 1.00 37.34  ? 382 VAL A CG2 1 
ATOM   6926 N N   . SER E 5 51  ? -4.286  16.824  -36.852 1.00 51.91  ? 383 SER A N   1 
ATOM   6927 C CA  . SER E 5 51  ? -3.225  17.360  -36.018 1.00 43.71  ? 383 SER A CA  1 
ATOM   6928 C C   . SER E 5 51  ? -3.846  18.073  -34.830 1.00 51.05  ? 383 SER A C   1 
ATOM   6929 O O   . SER E 5 51  ? -4.566  19.064  -35.026 1.00 63.64  ? 383 SER A O   1 
ATOM   6930 C CB  . SER E 5 51  ? -2.352  18.322  -36.814 1.00 54.67  ? 383 SER A CB  1 
ATOM   6931 O OG  . SER E 5 51  ? -1.831  17.696  -37.974 1.00 58.29  ? 383 SER A OG  1 
ATOM   6932 N N   . PRO E 5 52  ? -3.618  17.613  -33.597 1.00 55.61  ? 384 PRO A N   1 
ATOM   6933 C CA  . PRO E 5 52  ? -4.231  18.283  -32.438 1.00 61.11  ? 384 PRO A CA  1 
ATOM   6934 C C   . PRO E 5 52  ? -3.812  19.736  -32.271 1.00 63.00  ? 384 PRO A C   1 
ATOM   6935 O O   . PRO E 5 52  ? -4.548  20.503  -31.636 1.00 59.00  ? 384 PRO A O   1 
ATOM   6936 C CB  . PRO E 5 52  ? -3.774  17.424  -31.248 1.00 49.21  ? 384 PRO A CB  1 
ATOM   6937 C CG  . PRO E 5 52  ? -2.648  16.592  -31.770 1.00 58.55  ? 384 PRO A CG  1 
ATOM   6938 C CD  . PRO E 5 52  ? -2.906  16.384  -33.219 1.00 61.36  ? 384 PRO A CD  1 
ATOM   6939 N N   . THR E 5 53  ? -2.667  20.143  -32.816 1.00 57.29  ? 385 THR A N   1 
ATOM   6940 C CA  . THR E 5 53  ? -2.251  21.539  -32.759 1.00 53.52  ? 385 THR A CA  1 
ATOM   6941 C C   . THR E 5 53  ? -2.778  22.368  -33.920 1.00 51.54  ? 385 THR A C   1 
ATOM   6942 O O   . THR E 5 53  ? -2.573  23.587  -33.932 1.00 60.44  ? 385 THR A O   1 
ATOM   6943 C CB  . THR E 5 53  ? -0.724  21.649  -32.735 1.00 51.68  ? 385 THR A CB  1 
ATOM   6944 O OG1 . THR E 5 53  ? -0.191  21.193  -33.984 1.00 56.06  ? 385 THR A OG1 1 
ATOM   6945 C CG2 . THR E 5 53  ? -0.150  20.817  -31.609 1.00 45.72  ? 385 THR A CG2 1 
ATOM   6946 N N   . LYS E 5 54  ? -3.442  21.745  -34.892 1.00 57.03  ? 386 LYS A N   1 
ATOM   6947 C CA  . LYS E 5 54  ? -3.958  22.442  -36.063 1.00 68.87  ? 386 LYS A CA  1 
ATOM   6948 C C   . LYS E 5 54  ? -5.480  22.392  -36.121 1.00 71.12  ? 386 LYS A C   1 
ATOM   6949 O O   . LYS E 5 54  ? -6.072  22.454  -37.200 1.00 65.78  ? 386 LYS A O   1 
ATOM   6950 C CB  . LYS E 5 54  ? -3.356  21.863  -37.339 1.00 52.37  ? 386 LYS A CB  1 
ATOM   6951 C CG  . LYS E 5 54  ? -1.880  22.116  -37.460 1.00 57.81  ? 386 LYS A CG  1 
ATOM   6952 C CD  . LYS E 5 54  ? -1.262  21.247  -38.527 1.00 55.62  ? 386 LYS A CD  1 
ATOM   6953 C CE  . LYS E 5 54  ? 0.216   21.544  -38.635 1.00 61.62  ? 386 LYS A CE  1 
ATOM   6954 N NZ  . LYS E 5 54  ? 0.782   21.900  -37.296 1.00 58.14  ? 386 LYS A NZ  1 
ATOM   6955 N N   . LEU E 5 55  ? -6.122  22.277  -34.961 1.00 79.21  ? 387 LEU A N   1 
ATOM   6956 C CA  . LEU E 5 55  ? -7.571  22.285  -34.871 1.00 82.37  ? 387 LEU A CA  1 
ATOM   6957 C C   . LEU E 5 55  ? -8.127  23.583  -34.307 1.00 86.33  ? 387 LEU A C   1 
ATOM   6958 O O   . LEU E 5 55  ? -9.342  23.799  -34.376 1.00 92.45  ? 387 LEU A O   1 
ATOM   6959 C CB  . LEU E 5 55  ? -8.050  21.110  -34.008 1.00 77.04  ? 387 LEU A CB  1 
ATOM   6960 C CG  . LEU E 5 55  ? -7.793  19.730  -34.609 1.00 70.31  ? 387 LEU A CG  1 
ATOM   6961 C CD1 . LEU E 5 55  ? -8.132  18.634  -33.625 1.00 64.54  ? 387 LEU A CD1 1 
ATOM   6962 C CD2 . LEU E 5 55  ? -8.616  19.579  -35.874 1.00 62.99  ? 387 LEU A CD2 1 
ATOM   6963 N N   . ASN E 5 56  ? -7.276  24.447  -33.749 1.00 91.55  ? 388 ASN A N   1 
ATOM   6964 C CA  . ASN E 5 56  ? -7.756  25.711  -33.205 1.00 94.61  ? 388 ASN A CA  1 
ATOM   6965 C C   . ASN E 5 56  ? -8.320  26.612  -34.296 1.00 91.79  ? 388 ASN A C   1 
ATOM   6966 O O   . ASN E 5 56  ? -9.224  27.414  -34.034 1.00 96.57  ? 388 ASN A O   1 
ATOM   6967 C CB  . ASN E 5 56  ? -6.624  26.416  -32.455 1.00 86.32  ? 388 ASN A CB  1 
ATOM   6968 C CG  . ASN E 5 56  ? -5.934  25.506  -31.454 1.00 100.16 ? 388 ASN A CG  1 
ATOM   6969 O OD1 . ASN E 5 56  ? -6.536  24.566  -30.934 1.00 95.30  ? 388 ASN A OD1 1 
ATOM   6970 N ND2 . ASN E 5 56  ? -4.661  25.778  -31.183 1.00 100.98 ? 388 ASN A ND2 1 
ATOM   6971 N N   . ASP E 5 57  ? -7.806  26.498  -35.518 1.00 77.53  ? 389 ASP A N   1 
ATOM   6972 C CA  . ASP E 5 57  ? -8.288  27.284  -36.645 1.00 80.94  ? 389 ASP A CA  1 
ATOM   6973 C C   . ASP E 5 57  ? -9.390  26.582  -37.427 1.00 78.08  ? 389 ASP A C   1 
ATOM   6974 O O   . ASP E 5 57  ? -9.919  27.163  -38.381 1.00 67.94  ? 389 ASP A O   1 
ATOM   6975 C CB  . ASP E 5 57  ? -7.123  27.627  -37.584 1.00 92.49  ? 389 ASP A CB  1 
ATOM   6976 C CG  . ASP E 5 57  ? -6.288  26.412  -37.947 1.00 100.41 ? 389 ASP A CG  1 
ATOM   6977 O OD1 . ASP E 5 57  ? -6.578  25.310  -37.434 1.00 103.97 ? 389 ASP A OD1 1 
ATOM   6978 O OD2 . ASP E 5 57  ? -5.338  26.561  -38.746 1.00 86.03  ? 389 ASP A OD2 1 
ATOM   6979 N N   . LEU E 5 58  ? -9.750  25.358  -37.052 1.00 85.26  ? 390 LEU A N   1 
ATOM   6980 C CA  . LEU E 5 58  ? -10.767 24.585  -37.753 1.00 86.06  ? 390 LEU A CA  1 
ATOM   6981 C C   . LEU E 5 58  ? -12.016 24.445  -36.891 1.00 83.45  ? 390 LEU A C   1 
ATOM   6982 O O   . LEU E 5 58  ? -11.937 24.345  -35.663 1.00 86.90  ? 390 LEU A O   1 
ATOM   6983 C CB  . LEU E 5 58  ? -10.226 23.200  -38.143 1.00 75.27  ? 390 LEU A CB  1 
ATOM   6984 C CG  . LEU E 5 58  ? -11.074 22.105  -38.813 1.00 78.24  ? 390 LEU A CG  1 
ATOM   6985 C CD1 . LEU E 5 58  ? -12.028 22.643  -39.864 1.00 81.80  ? 390 LEU A CD1 1 
ATOM   6986 C CD2 . LEU E 5 58  ? -10.152 21.077  -39.453 1.00 65.09  ? 390 LEU A CD2 1 
ATOM   6987 N N   . CYS E 5 59  ? -13.174 24.441  -37.553 1.00 79.40  ? 391 CYS A N   1 
ATOM   6988 C CA  . CYS E 5 59  ? -14.478 24.342  -36.909 1.00 87.80  ? 391 CYS A CA  1 
ATOM   6989 C C   . CYS E 5 59  ? -15.171 23.060  -37.350 1.00 74.31  ? 391 CYS A C   1 
ATOM   6990 O O   . CYS E 5 59  ? -15.058 22.652  -38.511 1.00 67.86  ? 391 CYS A O   1 
ATOM   6991 C CB  . CYS E 5 59  ? -15.370 25.547  -37.249 1.00 86.82  ? 391 CYS A CB  1 
ATOM   6992 S SG  . CYS E 5 59  ? -14.802 27.145  -36.646 1.00 123.32 ? 391 CYS A SG  1 
ATOM   6993 N N   . PHE E 5 60  ? -15.890 22.434  -36.419 1.00 73.99  ? 392 PHE A N   1 
ATOM   6994 C CA  . PHE E 5 60  ? -16.616 21.194  -36.666 1.00 70.27  ? 392 PHE A CA  1 
ATOM   6995 C C   . PHE E 5 60  ? -18.072 21.367  -36.256 1.00 66.20  ? 392 PHE A C   1 
ATOM   6996 O O   . PHE E 5 60  ? -18.444 22.351  -35.613 1.00 76.17  ? 392 PHE A O   1 
ATOM   6997 C CB  . PHE E 5 60  ? -16.010 20.020  -35.892 1.00 55.94  ? 392 PHE A CB  1 
ATOM   6998 C CG  . PHE E 5 60  ? -14.568 19.785  -36.184 1.00 71.69  ? 392 PHE A CG  1 
ATOM   6999 C CD1 . PHE E 5 60  ? -13.591 20.589  -35.610 1.00 84.33  ? 392 PHE A CD1 1 
ATOM   7000 C CD2 . PHE E 5 60  ? -14.178 18.761  -37.029 1.00 71.85  ? 392 PHE A CD2 1 
ATOM   7001 C CE1 . PHE E 5 60  ? -12.251 20.382  -35.874 1.00 81.63  ? 392 PHE A CE1 1 
ATOM   7002 C CE2 . PHE E 5 60  ? -12.835 18.548  -37.295 1.00 69.58  ? 392 PHE A CE2 1 
ATOM   7003 C CZ  . PHE E 5 60  ? -11.870 19.358  -36.716 1.00 72.94  ? 392 PHE A CZ  1 
ATOM   7004 N N   . THR E 5 61  ? -18.902 20.393  -36.629 1.00 65.25  ? 393 THR A N   1 
ATOM   7005 C CA  . THR E 5 61  ? -20.298 20.392  -36.204 1.00 64.84  ? 393 THR A CA  1 
ATOM   7006 C C   . THR E 5 61  ? -20.470 19.705  -34.853 1.00 64.75  ? 393 THR A C   1 
ATOM   7007 O O   . THR E 5 61  ? -21.145 20.233  -33.964 1.00 70.64  ? 393 THR A O   1 
ATOM   7008 C CB  . THR E 5 61  ? -21.177 19.707  -37.254 1.00 64.59  ? 393 THR A CB  1 
ATOM   7009 O OG1 . THR E 5 61  ? -21.182 18.293  -37.027 1.00 65.23  ? 393 THR A OG1 1 
ATOM   7010 C CG2 . THR E 5 61  ? -20.637 19.982  -38.642 1.00 78.17  ? 393 THR A CG2 1 
ATOM   7011 N N   . ASN E 5 62  ? -19.867 18.530  -34.688 1.00 62.38  ? 394 ASN A N   1 
ATOM   7012 C CA  . ASN E 5 62  ? -19.892 17.817  -33.421 1.00 47.94  ? 394 ASN A CA  1 
ATOM   7013 C C   . ASN E 5 62  ? -18.560 17.118  -33.197 1.00 45.86  ? 394 ASN A C   1 
ATOM   7014 O O   . ASN E 5 62  ? -17.910 16.660  -34.142 1.00 58.22  ? 394 ASN A O   1 
ATOM   7015 C CB  . ASN E 5 62  ? -21.027 16.784  -33.361 1.00 49.32  ? 394 ASN A CB  1 
ATOM   7016 C CG  . ASN E 5 62  ? -22.366 17.406  -33.019 1.00 53.49  ? 394 ASN A CG  1 
ATOM   7017 O OD1 . ASN E 5 62  ? -23.419 16.864  -33.354 1.00 67.09  ? 394 ASN A OD1 1 
ATOM   7018 N ND2 . ASN E 5 62  ? -22.333 18.550  -32.351 1.00 55.48  ? 394 ASN A ND2 1 
ATOM   7019 N N   . VAL E 5 63  ? -18.163 17.039  -31.930 1.00 36.42  ? 395 VAL A N   1 
ATOM   7020 C CA  . VAL E 5 63  ? -16.998 16.276  -31.503 1.00 38.46  ? 395 VAL A CA  1 
ATOM   7021 C C   . VAL E 5 63  ? -17.449 15.309  -30.419 1.00 49.88  ? 395 VAL A C   1 
ATOM   7022 O O   . VAL E 5 63  ? -18.114 15.713  -29.459 1.00 55.06  ? 395 VAL A O   1 
ATOM   7023 C CB  . VAL E 5 63  ? -15.867 17.186  -30.985 1.00 34.02  ? 395 VAL A CB  1 
ATOM   7024 C CG1 . VAL E 5 63  ? -14.715 16.349  -30.445 1.00 31.71  ? 395 VAL A CG1 1 
ATOM   7025 C CG2 . VAL E 5 63  ? -15.383 18.113  -32.089 1.00 49.53  ? 395 VAL A CG2 1 
ATOM   7026 N N   . TYR E 5 64  ? -17.098 14.037  -30.574 1.00 41.34  ? 396 TYR A N   1 
ATOM   7027 C CA  . TYR E 5 64  ? -17.491 12.996  -29.637 1.00 39.73  ? 396 TYR A CA  1 
ATOM   7028 C C   . TYR E 5 64  ? -16.290 12.581  -28.801 1.00 34.57  ? 396 TYR A C   1 
ATOM   7029 O O   . TYR E 5 64  ? -15.195 12.376  -29.336 1.00 38.94  ? 396 TYR A O   1 
ATOM   7030 C CB  . TYR E 5 64  ? -18.073 11.786  -30.371 1.00 36.62  ? 396 TYR A CB  1 
ATOM   7031 C CG  . TYR E 5 64  ? -19.356 12.094  -31.105 1.00 38.57  ? 396 TYR A CG  1 
ATOM   7032 C CD1 . TYR E 5 64  ? -20.508 12.438  -30.410 1.00 44.23  ? 396 TYR A CD1 1 
ATOM   7033 C CD2 . TYR E 5 64  ? -19.418 12.040  -32.491 1.00 41.10  ? 396 TYR A CD2 1 
ATOM   7034 C CE1 . TYR E 5 64  ? -21.685 12.722  -31.074 1.00 47.13  ? 396 TYR A CE1 1 
ATOM   7035 C CE2 . TYR E 5 64  ? -20.591 12.321  -33.165 1.00 37.10  ? 396 TYR A CE2 1 
ATOM   7036 C CZ  . TYR E 5 64  ? -21.721 12.662  -32.451 1.00 48.34  ? 396 TYR A CZ  1 
ATOM   7037 O OH  . TYR E 5 64  ? -22.892 12.943  -33.118 1.00 59.79  ? 396 TYR A OH  1 
ATOM   7038 N N   . ALA E 5 65  ? -16.499 12.471  -27.492 1.00 32.47  ? 397 ALA A N   1 
ATOM   7039 C CA  . ALA E 5 65  ? -15.481 12.009  -26.555 1.00 30.98  ? 397 ALA A CA  1 
ATOM   7040 C C   . ALA E 5 65  ? -15.961 10.698  -25.947 1.00 32.79  ? 397 ALA A C   1 
ATOM   7041 O O   . ALA E 5 65  ? -16.847 10.695  -25.085 1.00 30.10  ? 397 ALA A O   1 
ATOM   7042 C CB  . ALA E 5 65  ? -15.214 13.055  -25.474 1.00 29.91  ? 397 ALA A CB  1 
ATOM   7043 N N   . ASP E 5 66  ? -15.381 9.589   -26.396 1.00 30.32  ? 398 ASP A N   1 
ATOM   7044 C CA  . ASP E 5 66  ? -15.715 8.265   -25.889 1.00 26.59  ? 398 ASP A CA  1 
ATOM   7045 C C   . ASP E 5 66  ? -14.736 7.892   -24.786 1.00 23.70  ? 398 ASP A C   1 
ATOM   7046 O O   . ASP E 5 66  ? -13.521 7.999   -24.971 1.00 35.57  ? 398 ASP A O   1 
ATOM   7047 C CB  . ASP E 5 66  ? -15.675 7.224   -27.009 1.00 40.30  ? 398 ASP A CB  1 
ATOM   7048 C CG  . ASP E 5 66  ? -16.661 7.526   -28.120 1.00 46.44  ? 398 ASP A CG  1 
ATOM   7049 O OD1 . ASP E 5 66  ? -17.777 7.994   -27.813 1.00 29.19  ? 398 ASP A OD1 1 
ATOM   7050 O OD2 . ASP E 5 66  ? -16.317 7.302   -29.300 1.00 46.27  ? 398 ASP A OD2 1 
ATOM   7051 N N   . SER E 5 67  ? -15.264 7.454   -23.644 1.00 26.74  ? 399 SER A N   1 
ATOM   7052 C CA  . SER E 5 67  ? -14.449 7.141   -22.478 1.00 26.46  ? 399 SER A CA  1 
ATOM   7053 C C   . SER E 5 67  ? -14.821 5.773   -21.922 1.00 25.48  ? 399 SER A C   1 
ATOM   7054 O O   . SER E 5 67  ? -15.998 5.401   -21.900 1.00 32.27  ? 399 SER A O   1 
ATOM   7055 C CB  . SER E 5 67  ? -14.608 8.211   -21.390 1.00 37.35  ? 399 SER A CB  1 
ATOM   7056 O OG  . SER E 5 67  ? -15.974 8.483   -21.131 1.00 46.92  ? 399 SER A OG  1 
ATOM   7057 N N   . PHE E 5 68  ? -13.809 5.035   -21.473 1.00 34.30  ? 400 PHE A N   1 
ATOM   7058 C CA  . PHE E 5 68  ? -13.970 3.702   -20.896 1.00 32.05  ? 400 PHE A CA  1 
ATOM   7059 C C   . PHE E 5 68  ? -12.627 3.277   -20.308 1.00 40.09  ? 400 PHE A C   1 
ATOM   7060 O O   . PHE E 5 68  ? -11.620 3.980   -20.441 1.00 36.04  ? 400 PHE A O   1 
ATOM   7061 C CB  . PHE E 5 68  ? -14.471 2.695   -21.933 1.00 30.99  ? 400 PHE A CB  1 
ATOM   7062 C CG  . PHE E 5 68  ? -13.704 2.726   -23.221 1.00 39.37  ? 400 PHE A CG  1 
ATOM   7063 C CD1 . PHE E 5 68  ? -12.570 1.949   -23.386 1.00 28.05  ? 400 PHE A CD1 1 
ATOM   7064 C CD2 . PHE E 5 68  ? -14.116 3.534   -24.268 1.00 37.53  ? 400 PHE A CD2 1 
ATOM   7065 C CE1 . PHE E 5 68  ? -11.861 1.976   -24.570 1.00 20.28  ? 400 PHE A CE1 1 
ATOM   7066 C CE2 . PHE E 5 68  ? -13.411 3.566   -25.453 1.00 32.44  ? 400 PHE A CE2 1 
ATOM   7067 C CZ  . PHE E 5 68  ? -12.282 2.786   -25.605 1.00 28.82  ? 400 PHE A CZ  1 
ATOM   7068 N N   . VAL E 5 69  ? -12.620 2.116   -19.654 1.00 38.44  ? 401 VAL A N   1 
ATOM   7069 C CA  . VAL E 5 69  ? -11.424 1.562   -19.026 1.00 32.96  ? 401 VAL A CA  1 
ATOM   7070 C C   . VAL E 5 69  ? -11.173 0.174   -19.595 1.00 39.95  ? 401 VAL A C   1 
ATOM   7071 O O   . VAL E 5 69  ? -12.090 -0.654  -19.659 1.00 43.95  ? 401 VAL A O   1 
ATOM   7072 C CB  . VAL E 5 69  ? -11.555 1.503   -17.493 1.00 35.39  ? 401 VAL A CB  1 
ATOM   7073 C CG1 . VAL E 5 69  ? -10.399 0.719   -16.890 1.00 34.95  ? 401 VAL A CG1 1 
ATOM   7074 C CG2 . VAL E 5 69  ? -11.590 2.898   -16.917 1.00 44.66  ? 401 VAL A CG2 1 
ATOM   7075 N N   . ILE E 5 70  ? -9.932  -0.076  -20.007 1.00 43.01  ? 402 ILE A N   1 
ATOM   7076 C CA  . ILE E 5 70  ? -9.495  -1.367  -20.510 1.00 42.02  ? 402 ILE A CA  1 
ATOM   7077 C C   . ILE E 5 70  ? -8.166  -1.718  -19.850 1.00 37.00  ? 402 ILE A C   1 
ATOM   7078 O O   . ILE E 5 70  ? -7.652  -0.982  -19.010 1.00 44.72  ? 402 ILE A O   1 
ATOM   7079 C CB  . ILE E 5 70  ? -9.365  -1.382  -22.047 1.00 36.40  ? 402 ILE A CB  1 
ATOM   7080 C CG1 . ILE E 5 70  ? -8.431  -0.262  -22.507 1.00 31.95  ? 402 ILE A CG1 1 
ATOM   7081 C CG2 . ILE E 5 70  ? -10.730 -1.251  -22.705 1.00 32.35  ? 402 ILE A CG2 1 
ATOM   7082 C CD1 . ILE E 5 70  ? -8.325  -0.138  -24.004 1.00 22.25  ? 402 ILE A CD1 1 
ATOM   7083 N N   . ARG E 5 71  ? -7.614  -2.862  -20.240 1.00 48.15  ? 403 ARG A N   1 
ATOM   7084 C CA  . ARG E 5 71  ? -6.297  -3.259  -19.770 1.00 38.71  ? 403 ARG A CA  1 
ATOM   7085 C C   . ARG E 5 71  ? -5.209  -2.594  -20.610 1.00 43.42  ? 403 ARG A C   1 
ATOM   7086 O O   . ARG E 5 71  ? -5.461  -2.057  -21.692 1.00 48.15  ? 403 ARG A O   1 
ATOM   7087 C CB  . ARG E 5 71  ? -6.141  -4.779  -19.819 1.00 32.21  ? 403 ARG A CB  1 
ATOM   7088 C CG  . ARG E 5 71  ? -7.049  -5.533  -18.863 1.00 43.00  ? 403 ARG A CG  1 
ATOM   7089 C CD  . ARG E 5 71  ? -6.900  -7.037  -19.040 1.00 41.14  ? 403 ARG A CD  1 
ATOM   7090 N NE  . ARG E 5 71  ? -5.501  -7.437  -19.122 1.00 50.22  ? 403 ARG A NE  1 
ATOM   7091 C CZ  . ARG E 5 71  ? -5.080  -8.695  -19.138 1.00 56.91  ? 403 ARG A CZ  1 
ATOM   7092 N NH1 . ARG E 5 71  ? -5.927  -9.708  -19.056 1.00 54.10  ? 403 ARG A NH1 1 
ATOM   7093 N NH2 . ARG E 5 71  ? -3.777  -8.942  -19.236 1.00 57.91  ? 403 ARG A NH2 1 
ATOM   7094 N N   . GLY E 5 72  ? -3.982  -2.629  -20.088 1.00 50.20  ? 404 GLY A N   1 
ATOM   7095 C CA  . GLY E 5 72  ? -2.854  -2.123  -20.854 1.00 41.42  ? 404 GLY A CA  1 
ATOM   7096 C C   . GLY E 5 72  ? -2.598  -2.934  -22.109 1.00 49.02  ? 404 GLY A C   1 
ATOM   7097 O O   . GLY E 5 72  ? -2.244  -2.383  -23.155 1.00 42.74  ? 404 GLY A O   1 
ATOM   7098 N N   . ASP E 5 73  ? -2.779  -4.256  -22.023 1.00 53.73  ? 405 ASP A N   1 
ATOM   7099 C CA  . ASP E 5 73  ? -2.611  -5.114  -23.193 1.00 48.40  ? 405 ASP A CA  1 
ATOM   7100 C C   . ASP E 5 73  ? -3.596  -4.760  -24.299 1.00 50.87  ? 405 ASP A C   1 
ATOM   7101 O O   . ASP E 5 73  ? -3.298  -4.960  -25.482 1.00 51.15  ? 405 ASP A O   1 
ATOM   7102 C CB  . ASP E 5 73  ? -2.791  -6.582  -22.801 1.00 43.84  ? 405 ASP A CB  1 
ATOM   7103 C CG  . ASP E 5 73  ? -1.848  -7.016  -21.700 1.00 63.19  ? 405 ASP A CG  1 
ATOM   7104 O OD1 . ASP E 5 73  ? -0.679  -6.578  -21.706 1.00 75.11  ? 405 ASP A OD1 1 
ATOM   7105 O OD2 . ASP E 5 73  ? -2.278  -7.802  -20.829 1.00 72.47  ? 405 ASP A OD2 1 
ATOM   7106 N N   . GLU E 5 74  ? -4.766  -4.242  -23.938 1.00 41.03  ? 406 GLU A N   1 
ATOM   7107 C CA  . GLU E 5 74  ? -5.858  -4.035  -24.878 1.00 36.35  ? 406 GLU A CA  1 
ATOM   7108 C C   . GLU E 5 74  ? -5.902  -2.627  -25.460 1.00 41.54  ? 406 GLU A C   1 
ATOM   7109 O O   . GLU E 5 74  ? -6.773  -2.347  -26.291 1.00 45.16  ? 406 GLU A O   1 
ATOM   7110 C CB  . GLU E 5 74  ? -7.189  -4.358  -24.195 1.00 37.90  ? 406 GLU A CB  1 
ATOM   7111 C CG  . GLU E 5 74  ? -7.244  -5.766  -23.619 1.00 46.56  ? 406 GLU A CG  1 
ATOM   7112 C CD  . GLU E 5 74  ? -8.367  -5.947  -22.619 1.00 48.64  ? 406 GLU A CD  1 
ATOM   7113 O OE1 . GLU E 5 74  ? -8.953  -4.930  -22.192 1.00 54.84  ? 406 GLU A OE1 1 
ATOM   7114 O OE2 . GLU E 5 74  ? -8.672  -7.107  -22.268 1.00 52.34  ? 406 GLU A OE2 1 
ATOM   7115 N N   . VAL E 5 75  ? -4.992  -1.739  -25.055 1.00 41.41  ? 407 VAL A N   1 
ATOM   7116 C CA  . VAL E 5 75  ? -4.983  -0.387  -25.606 1.00 34.11  ? 407 VAL A CA  1 
ATOM   7117 C C   . VAL E 5 75  ? -4.652  -0.420  -27.093 1.00 36.15  ? 407 VAL A C   1 
ATOM   7118 O O   . VAL E 5 75  ? -5.187  0.370   -27.881 1.00 27.52  ? 407 VAL A O   1 
ATOM   7119 C CB  . VAL E 5 75  ? -4.006  0.507   -24.821 1.00 30.04  ? 407 VAL A CB  1 
ATOM   7120 C CG1 . VAL E 5 75  ? -3.909  1.885   -25.458 1.00 13.80  ? 407 VAL A CG1 1 
ATOM   7121 C CG2 . VAL E 5 75  ? -4.448  0.624   -23.371 1.00 40.95  ? 407 VAL A CG2 1 
ATOM   7122 N N   . ARG E 5 76  ? -3.778  -1.343  -27.504 1.00 43.23  ? 408 ARG A N   1 
ATOM   7123 C CA  . ARG E 5 76  ? -3.440  -1.479  -28.916 1.00 33.25  ? 408 ARG A CA  1 
ATOM   7124 C C   . ARG E 5 76  ? -4.659  -1.792  -29.774 1.00 39.21  ? 408 ARG A C   1 
ATOM   7125 O O   . ARG E 5 76  ? -4.647  -1.502  -30.975 1.00 37.94  ? 408 ARG A O   1 
ATOM   7126 C CB  . ARG E 5 76  ? -2.380  -2.567  -29.098 1.00 41.10  ? 408 ARG A CB  1 
ATOM   7127 C CG  . ARG E 5 76  ? -2.874  -3.965  -28.763 1.00 43.56  ? 408 ARG A CG  1 
ATOM   7128 C CD  . ARG E 5 76  ? -1.725  -4.910  -28.458 1.00 55.36  ? 408 ARG A CD  1 
ATOM   7129 N NE  . ARG E 5 76  ? -0.889  -4.407  -27.375 1.00 71.53  ? 408 ARG A NE  1 
ATOM   7130 C CZ  . ARG E 5 76  ? -0.091  -5.160  -26.630 1.00 68.42  ? 408 ARG A CZ  1 
ATOM   7131 N NH1 . ARG E 5 76  ? -0.014  -6.469  -26.806 1.00 65.62  ? 408 ARG A NH1 1 
ATOM   7132 N NH2 . ARG E 5 76  ? 0.641   -4.586  -25.680 1.00 69.14  ? 408 ARG A NH2 1 
ATOM   7133 N N   . GLN E 5 77  ? -5.708  -2.374  -29.188 1.00 39.35  ? 409 GLN A N   1 
ATOM   7134 C CA  . GLN E 5 77  ? -6.925  -2.661  -29.937 1.00 33.74  ? 409 GLN A CA  1 
ATOM   7135 C C   . GLN E 5 77  ? -7.751  -1.414  -30.230 1.00 31.12  ? 409 GLN A C   1 
ATOM   7136 O O   . GLN E 5 77  ? -8.664  -1.484  -31.059 1.00 41.90  ? 409 GLN A O   1 
ATOM   7137 C CB  . GLN E 5 77  ? -7.785  -3.679  -29.183 1.00 38.71  ? 409 GLN A CB  1 
ATOM   7138 C CG  . GLN E 5 77  ? -7.125  -5.036  -28.990 1.00 29.40  ? 409 GLN A CG  1 
ATOM   7139 C CD  . GLN E 5 77  ? -8.074  -6.075  -28.417 1.00 28.26  ? 409 GLN A CD  1 
ATOM   7140 O OE1 . GLN E 5 77  ? -9.270  -6.071  -28.712 1.00 29.62  ? 409 GLN A OE1 1 
ATOM   7141 N NE2 . GLN E 5 77  ? -7.544  -6.969  -27.590 1.00 35.75  ? 409 GLN A NE2 1 
ATOM   7142 N N   . ILE E 5 78  ? -7.462  -0.288  -29.584 1.00 30.99  ? 410 ILE A N   1 
ATOM   7143 C CA  . ILE E 5 78  ? -8.203  0.960   -29.841 1.00 39.13  ? 410 ILE A CA  1 
ATOM   7144 C C   . ILE E 5 78  ? -7.483  1.642   -30.997 1.00 41.79  ? 410 ILE A C   1 
ATOM   7145 O O   . ILE E 5 78  ? -6.681  2.565   -30.831 1.00 47.29  ? 410 ILE A O   1 
ATOM   7146 C CB  . ILE E 5 78  ? -8.296  1.846   -28.595 1.00 32.94  ? 410 ILE A CB  1 
ATOM   7147 C CG1 . ILE E 5 78  ? -8.777  1.034   -27.393 1.00 25.42  ? 410 ILE A CG1 1 
ATOM   7148 C CG2 . ILE E 5 78  ? -9.234  3.018   -28.846 1.00 30.11  ? 410 ILE A CG2 1 
ATOM   7149 C CD1 . ILE E 5 78  ? -10.230 0.622   -27.479 1.00 31.49  ? 410 ILE A CD1 1 
ATOM   7150 N N   . ALA E 5 79  ? -7.799  1.189   -32.208 1.00 34.22  ? 411 ALA A N   1 
ATOM   7151 C CA  . ALA E 5 79  ? -7.165  1.661   -33.432 1.00 39.78  ? 411 ALA A CA  1 
ATOM   7152 C C   . ALA E 5 79  ? -7.908  1.085   -34.630 1.00 45.55  ? 411 ALA A C   1 
ATOM   7153 O O   . ALA E 5 79  ? -8.477  -0.010  -34.536 1.00 46.65  ? 411 ALA A O   1 
ATOM   7154 C CB  . ALA E 5 79  ? -5.687  1.261   -33.473 1.00 46.60  ? 411 ALA A CB  1 
ATOM   7155 N N   . PRO E 5 80  ? -7.938  1.787   -35.762 1.00 36.87  ? 412 PRO A N   1 
ATOM   7156 C CA  . PRO E 5 80  ? -8.629  1.249   -36.939 1.00 30.55  ? 412 PRO A CA  1 
ATOM   7157 C C   . PRO E 5 80  ? -7.996  -0.049  -37.420 1.00 35.33  ? 412 PRO A C   1 
ATOM   7158 O O   . PRO E 5 80  ? -6.775  -0.220  -37.382 1.00 30.64  ? 412 PRO A O   1 
ATOM   7159 C CB  . PRO E 5 80  ? -8.483  2.367   -37.978 1.00 26.81  ? 412 PRO A CB  1 
ATOM   7160 C CG  . PRO E 5 80  ? -7.316  3.175   -37.512 1.00 30.23  ? 412 PRO A CG  1 
ATOM   7161 C CD  . PRO E 5 80  ? -7.362  3.118   -36.019 1.00 27.69  ? 412 PRO A CD  1 
ATOM   7162 N N   . GLY E 5 81  ? -8.846  -0.968  -37.876 1.00 38.74  ? 413 GLY A N   1 
ATOM   7163 C CA  . GLY E 5 81  ? -8.372  -2.213  -38.446 1.00 33.31  ? 413 GLY A CA  1 
ATOM   7164 C C   . GLY E 5 81  ? -7.818  -3.217  -37.462 1.00 22.17  ? 413 GLY A C   1 
ATOM   7165 O O   . GLY E 5 81  ? -7.010  -4.064  -37.850 1.00 27.89  ? 413 GLY A O   1 
ATOM   7166 N N   . GLN E 5 82  ? -8.228  -3.154  -36.200 1.00 28.54  ? 414 GLN A N   1 
ATOM   7167 C CA  . GLN E 5 82  ? -7.746  -4.069  -35.176 1.00 23.11  ? 414 GLN A CA  1 
ATOM   7168 C C   . GLN E 5 82  ? -8.794  -5.130  -34.861 1.00 27.44  ? 414 GLN A C   1 
ATOM   7169 O O   . GLN E 5 82  ? -9.990  -4.953  -35.106 1.00 43.18  ? 414 GLN A O   1 
ATOM   7170 C CB  . GLN E 5 82  ? -7.371  -3.308  -33.902 1.00 28.91  ? 414 GLN A CB  1 
ATOM   7171 C CG  . GLN E 5 82  ? -6.201  -2.360  -34.084 1.00 41.96  ? 414 GLN A CG  1 
ATOM   7172 C CD  . GLN E 5 82  ? -4.949  -3.073  -34.555 1.00 40.97  ? 414 GLN A CD  1 
ATOM   7173 O OE1 . GLN E 5 82  ? -4.371  -3.882  -33.829 1.00 33.87  ? 414 GLN A OE1 1 
ATOM   7174 N NE2 . GLN E 5 82  ? -4.528  -2.781  -35.781 1.00 34.66  ? 414 GLN A NE2 1 
ATOM   7175 N N   . THR E 5 83  ? -8.322  -6.248  -34.312 1.00 21.46  ? 415 THR A N   1 
ATOM   7176 C CA  . THR E 5 83  ? -9.180  -7.360  -33.928 1.00 26.17  ? 415 THR A CA  1 
ATOM   7177 C C   . THR E 5 83  ? -8.821  -7.824  -32.522 1.00 30.57  ? 415 THR A C   1 
ATOM   7178 O O   . THR E 5 83  ? -7.700  -7.629  -32.045 1.00 31.54  ? 415 THR A O   1 
ATOM   7179 C CB  . THR E 5 83  ? -9.065  -8.540  -34.908 1.00 27.04  ? 415 THR A CB  1 
ATOM   7180 O OG1 . THR E 5 83  ? -7.694  -8.940  -35.026 1.00 40.08  ? 415 THR A OG1 1 
ATOM   7181 C CG2 . THR E 5 83  ? -9.599  -8.156  -36.281 1.00 25.49  ? 415 THR A CG2 1 
ATOM   7182 N N   . GLY E 5 84  ? -9.788  -8.443  -31.869 1.00 27.21  ? 416 GLY A N   1 
ATOM   7183 C CA  . GLY E 5 84  ? -9.621  -8.909  -30.506 1.00 37.24  ? 416 GLY A CA  1 
ATOM   7184 C C   . GLY E 5 84  ? -10.940 -8.824  -29.766 1.00 34.97  ? 416 GLY A C   1 
ATOM   7185 O O   . GLY E 5 84  ? -11.962 -8.433  -30.317 1.00 37.99  ? 416 GLY A O   1 
ATOM   7186 N N   . LYS E 5 85  ? -10.889 -9.190  -28.483 1.00 33.82  ? 417 LYS A N   1 
ATOM   7187 C CA  . LYS E 5 85  ? -12.103 -9.179  -27.671 1.00 32.76  ? 417 LYS A CA  1 
ATOM   7188 C C   . LYS E 5 85  ? -12.703 -7.781  -27.591 1.00 33.20  ? 417 LYS A C   1 
ATOM   7189 O O   . LYS E 5 85  ? -13.928 -7.617  -27.655 1.00 39.32  ? 417 LYS A O   1 
ATOM   7190 C CB  . LYS E 5 85  ? -11.805 -9.701  -26.266 1.00 32.34  ? 417 LYS A CB  1 
ATOM   7191 C CG  . LYS E 5 85  ? -11.463 -11.176 -26.194 1.00 33.73  ? 417 LYS A CG  1 
ATOM   7192 C CD  . LYS E 5 85  ? -10.861 -11.515 -24.841 1.00 40.62  ? 417 LYS A CD  1 
ATOM   7193 C CE  . LYS E 5 85  ? -10.283 -12.919 -24.820 1.00 58.23  ? 417 LYS A CE  1 
ATOM   7194 N NZ  . LYS E 5 85  ? -11.344 -13.952 -24.693 1.00 57.90  ? 417 LYS A NZ  1 
ATOM   7195 N N   . ILE E 5 86  ? -11.858 -6.762  -27.450 1.00 24.00  ? 418 ILE A N   1 
ATOM   7196 C CA  . ILE E 5 86  ? -12.357 -5.413  -27.214 1.00 33.14  ? 418 ILE A CA  1 
ATOM   7197 C C   . ILE E 5 86  ? -12.790 -4.757  -28.522 1.00 39.16  ? 418 ILE A C   1 
ATOM   7198 O O   . ILE E 5 86  ? -13.842 -4.110  -28.587 1.00 38.26  ? 418 ILE A O   1 
ATOM   7199 C CB  . ILE E 5 86  ? -11.295 -4.579  -26.471 1.00 26.75  ? 418 ILE A CB  1 
ATOM   7200 C CG1 . ILE E 5 86  ? -11.343 -4.848  -24.959 1.00 24.95  ? 418 ILE A CG1 1 
ATOM   7201 C CG2 . ILE E 5 86  ? -11.492 -3.094  -26.732 1.00 31.27  ? 418 ILE A CG2 1 
ATOM   7202 C CD1 . ILE E 5 86  ? -11.044 -6.281  -24.534 1.00 41.68  ? 418 ILE A CD1 1 
ATOM   7203 N N   . ALA E 5 87  ? -11.994 -4.914  -29.582 1.00 36.59  ? 419 ALA A N   1 
ATOM   7204 C CA  . ALA E 5 87  ? -12.353 -4.326  -30.869 1.00 35.00  ? 419 ALA A CA  1 
ATOM   7205 C C   . ALA E 5 87  ? -13.573 -5.010  -31.477 1.00 41.58  ? 419 ALA A C   1 
ATOM   7206 O O   . ALA E 5 87  ? -14.434 -4.345  -32.066 1.00 42.67  ? 419 ALA A O   1 
ATOM   7207 C CB  . ALA E 5 87  ? -11.164 -4.395  -31.826 1.00 29.96  ? 419 ALA A CB  1 
ATOM   7208 N N   . ASP E 5 88  ? -13.665 -6.337  -31.353 1.00 40.30  ? 420 ASP A N   1 
ATOM   7209 C CA  . ASP E 5 88  ? -14.769 -7.060  -31.978 1.00 36.89  ? 420 ASP A CA  1 
ATOM   7210 C C   . ASP E 5 88  ? -16.071 -6.916  -31.197 1.00 41.27  ? 420 ASP A C   1 
ATOM   7211 O O   . ASP E 5 88  ? -17.142 -6.783  -31.799 1.00 34.00  ? 420 ASP A O   1 
ATOM   7212 C CB  . ASP E 5 88  ? -14.420 -8.542  -32.128 1.00 31.99  ? 420 ASP A CB  1 
ATOM   7213 C CG  . ASP E 5 88  ? -13.201 -8.773  -33.000 1.00 42.96  ? 420 ASP A CG  1 
ATOM   7214 O OD1 . ASP E 5 88  ? -12.741 -7.815  -33.656 1.00 37.73  ? 420 ASP A OD1 1 
ATOM   7215 O OD2 . ASP E 5 88  ? -12.696 -9.916  -33.021 1.00 50.95  ? 420 ASP A OD2 1 
ATOM   7216 N N   . TYR E 5 89  ? -16.007 -6.943  -29.864 1.00 37.87  ? 421 TYR A N   1 
ATOM   7217 C CA  . TYR E 5 89  ? -17.206 -7.093  -29.053 1.00 27.31  ? 421 TYR A CA  1 
ATOM   7218 C C   . TYR E 5 89  ? -17.518 -5.913  -28.144 1.00 33.10  ? 421 TYR A C   1 
ATOM   7219 O O   . TYR E 5 89  ? -18.632 -5.854  -27.609 1.00 34.82  ? 421 TYR A O   1 
ATOM   7220 C CB  . TYR E 5 89  ? -17.108 -8.359  -28.186 1.00 29.49  ? 421 TYR A CB  1 
ATOM   7221 C CG  . TYR E 5 89  ? -16.760 -9.617  -28.953 1.00 37.15  ? 421 TYR A CG  1 
ATOM   7222 C CD1 . TYR E 5 89  ? -17.266 -9.844  -30.227 1.00 34.89  ? 421 TYR A CD1 1 
ATOM   7223 C CD2 . TYR E 5 89  ? -15.920 -10.576 -28.403 1.00 30.59  ? 421 TYR A CD2 1 
ATOM   7224 C CE1 . TYR E 5 89  ? -16.947 -10.991 -30.930 1.00 34.81  ? 421 TYR A CE1 1 
ATOM   7225 C CE2 . TYR E 5 89  ? -15.596 -11.727 -29.097 1.00 33.20  ? 421 TYR A CE2 1 
ATOM   7226 C CZ  . TYR E 5 89  ? -16.112 -11.929 -30.361 1.00 39.42  ? 421 TYR A CZ  1 
ATOM   7227 O OH  . TYR E 5 89  ? -15.792 -13.072 -31.058 1.00 36.85  ? 421 TYR A OH  1 
ATOM   7228 N N   . ASN E 5 90  ? -16.586 -4.986  -27.933 1.00 35.79  ? 422 ASN A N   1 
ATOM   7229 C CA  . ASN E 5 90  ? -16.812 -3.903  -26.982 1.00 27.98  ? 422 ASN A CA  1 
ATOM   7230 C C   . ASN E 5 90  ? -16.766 -2.521  -27.615 1.00 32.73  ? 422 ASN A C   1 
ATOM   7231 O O   . ASN E 5 90  ? -17.723 -1.750  -27.470 1.00 37.88  ? 422 ASN A O   1 
ATOM   7232 C CB  . ASN E 5 90  ? -15.791 -4.003  -25.839 1.00 20.90  ? 422 ASN A CB  1 
ATOM   7233 C CG  . ASN E 5 90  ? -15.950 -5.277  -25.028 1.00 25.89  ? 422 ASN A CG  1 
ATOM   7234 O OD1 . ASN E 5 90  ? -16.605 -5.285  -23.987 1.00 40.00  ? 422 ASN A OD1 1 
ATOM   7235 N ND2 . ASN E 5 90  ? -15.357 -6.362  -25.507 1.00 30.86  ? 422 ASN A ND2 1 
ATOM   7236 N N   . TYR E 5 91  ? -15.688 -2.179  -28.318 1.00 34.08  ? 423 TYR A N   1 
ATOM   7237 C CA  . TYR E 5 91  ? -15.543 -0.845  -28.895 1.00 25.08  ? 423 TYR A CA  1 
ATOM   7238 C C   . TYR E 5 91  ? -14.731 -0.960  -30.173 1.00 23.80  ? 423 TYR A C   1 
ATOM   7239 O O   . TYR E 5 91  ? -13.588 -1.425  -30.142 1.00 35.51  ? 423 TYR A O   1 
ATOM   7240 C CB  . TYR E 5 91  ? -14.873 0.112   -27.905 1.00 30.74  ? 423 TYR A CB  1 
ATOM   7241 C CG  . TYR E 5 91  ? -14.806 1.551   -28.372 1.00 31.99  ? 423 TYR A CG  1 
ATOM   7242 C CD1 . TYR E 5 91  ? -15.929 2.368   -28.332 1.00 32.09  ? 423 TYR A CD1 1 
ATOM   7243 C CD2 . TYR E 5 91  ? -13.617 2.095   -28.839 1.00 28.60  ? 423 TYR A CD2 1 
ATOM   7244 C CE1 . TYR E 5 91  ? -15.871 3.684   -28.754 1.00 26.29  ? 423 TYR A CE1 1 
ATOM   7245 C CE2 . TYR E 5 91  ? -13.549 3.410   -29.262 1.00 29.53  ? 423 TYR A CE2 1 
ATOM   7246 C CZ  . TYR E 5 91  ? -14.679 4.199   -29.217 1.00 29.41  ? 423 TYR A CZ  1 
ATOM   7247 O OH  . TYR E 5 91  ? -14.617 5.508   -29.637 1.00 24.29  ? 423 TYR A OH  1 
ATOM   7248 N N   . LYS E 5 92  ? -15.316 -0.532  -31.289 1.00 27.76  ? 424 LYS A N   1 
ATOM   7249 C CA  . LYS E 5 92  ? -14.731 -0.713  -32.610 1.00 32.92  ? 424 LYS A CA  1 
ATOM   7250 C C   . LYS E 5 92  ? -14.519 0.640   -33.272 1.00 40.15  ? 424 LYS A C   1 
ATOM   7251 O O   . LYS E 5 92  ? -15.416 1.489   -33.262 1.00 38.11  ? 424 LYS A O   1 
ATOM   7252 C CB  . LYS E 5 92  ? -15.628 -1.593  -33.486 1.00 28.14  ? 424 LYS A CB  1 
ATOM   7253 C CG  . LYS E 5 92  ? -15.089 -1.830  -34.886 1.00 39.51  ? 424 LYS A CG  1 
ATOM   7254 C CD  . LYS E 5 92  ? -13.737 -2.525  -34.842 1.00 41.59  ? 424 LYS A CD  1 
ATOM   7255 C CE  . LYS E 5 92  ? -13.164 -2.704  -36.237 1.00 25.04  ? 424 LYS A CE  1 
ATOM   7256 N NZ  . LYS E 5 92  ? -11.839 -3.382  -36.210 1.00 33.39  ? 424 LYS A NZ  1 
ATOM   7257 N N   . LEU E 5 93  ? -13.335 0.834   -33.845 1.00 38.68  ? 425 LEU A N   1 
ATOM   7258 C CA  . LEU E 5 93  ? -13.096 2.047   -34.611 1.00 39.32  ? 425 LEU A CA  1 
ATOM   7259 C C   . LEU E 5 93  ? -13.201 1.767   -36.104 1.00 39.65  ? 425 LEU A C   1 
ATOM   7260 O O   . LEU E 5 93  ? -12.768 0.706   -36.569 1.00 39.31  ? 425 LEU A O   1 
ATOM   7261 C CB  . LEU E 5 93  ? -11.713 2.625   -34.306 1.00 33.84  ? 425 LEU A CB  1 
ATOM   7262 C CG  . LEU E 5 93  ? -11.564 3.423   -33.011 1.00 34.36  ? 425 LEU A CG  1 
ATOM   7263 C CD1 . LEU E 5 93  ? -10.143 3.943   -32.864 1.00 42.23  ? 425 LEU A CD1 1 
ATOM   7264 C CD2 . LEU E 5 93  ? -12.561 4.568   -32.976 1.00 30.92  ? 425 LEU A CD2 1 
ATOM   7265 N N   . PRO E 5 94  ? -13.772 2.692   -36.869 1.00 39.88  ? 426 PRO A N   1 
ATOM   7266 C CA  . PRO E 5 94  ? -13.814 2.523   -38.324 1.00 39.52  ? 426 PRO A CA  1 
ATOM   7267 C C   . PRO E 5 94  ? -12.419 2.599   -38.925 1.00 46.05  ? 426 PRO A C   1 
ATOM   7268 O O   . PRO E 5 94  ? -11.499 3.194   -38.360 1.00 48.84  ? 426 PRO A O   1 
ATOM   7269 C CB  . PRO E 5 94  ? -14.688 3.690   -38.795 1.00 37.26  ? 426 PRO A CB  1 
ATOM   7270 C CG  . PRO E 5 94  ? -14.539 4.719   -37.723 1.00 42.58  ? 426 PRO A CG  1 
ATOM   7271 C CD  . PRO E 5 94  ? -14.406 3.950   -36.439 1.00 38.01  ? 426 PRO A CD  1 
ATOM   7272 N N   . ASP E 5 95  ? -12.272 1.970   -40.093 1.00 52.20  ? 427 ASP A N   1 
ATOM   7273 C CA  . ASP E 5 95  ? -10.981 1.968   -40.775 1.00 46.35  ? 427 ASP A CA  1 
ATOM   7274 C C   . ASP E 5 95  ? -10.553 3.374   -41.175 1.00 43.74  ? 427 ASP A C   1 
ATOM   7275 O O   . ASP E 5 95  ? -9.353  3.670   -41.219 1.00 52.11  ? 427 ASP A O   1 
ATOM   7276 C CB  . ASP E 5 95  ? -11.039 1.060   -42.002 1.00 50.09  ? 427 ASP A CB  1 
ATOM   7277 C CG  . ASP E 5 95  ? -11.375 -0.374  -41.646 1.00 56.25  ? 427 ASP A CG  1 
ATOM   7278 O OD1 . ASP E 5 95  ? -11.383 -0.704  -40.440 1.00 52.04  ? 427 ASP A OD1 1 
ATOM   7279 O OD2 . ASP E 5 95  ? -11.635 -1.171  -42.571 1.00 46.17  ? 427 ASP A OD2 1 
ATOM   7280 N N   . ASP E 5 96  ? -11.515 4.251   -41.467 1.00 46.43  ? 428 ASP A N   1 
ATOM   7281 C CA  . ASP E 5 96  ? -11.246 5.641   -41.813 1.00 55.94  ? 428 ASP A CA  1 
ATOM   7282 C C   . ASP E 5 96  ? -11.384 6.569   -40.611 1.00 59.73  ? 428 ASP A C   1 
ATOM   7283 O O   . ASP E 5 96  ? -11.754 7.738   -40.769 1.00 70.21  ? 428 ASP A O   1 
ATOM   7284 C CB  . ASP E 5 96  ? -12.173 6.092   -42.941 1.00 56.43  ? 428 ASP A CB  1 
ATOM   7285 C CG  . ASP E 5 96  ? -13.636 6.044   -42.544 1.00 59.38  ? 428 ASP A CG  1 
ATOM   7286 O OD1 . ASP E 5 96  ? -13.999 5.183   -41.715 1.00 53.81  ? 428 ASP A OD1 1 
ATOM   7287 O OD2 . ASP E 5 96  ? -14.421 6.868   -43.059 1.00 58.53  ? 428 ASP A OD2 1 
ATOM   7288 N N   . PHE E 5 97  ? -11.100 6.064   -39.411 1.00 50.49  ? 429 PHE A N   1 
ATOM   7289 C CA  . PHE E 5 97  ? -11.268 6.856   -38.201 1.00 39.57  ? 429 PHE A CA  1 
ATOM   7290 C C   . PHE E 5 97  ? -10.385 8.095   -38.236 1.00 46.19  ? 429 PHE A C   1 
ATOM   7291 O O   . PHE E 5 97  ? -9.218  8.039   -38.633 1.00 42.15  ? 429 PHE A O   1 
ATOM   7292 C CB  . PHE E 5 97  ? -10.940 6.016   -36.967 1.00 36.28  ? 429 PHE A CB  1 
ATOM   7293 C CG  . PHE E 5 97  ? -10.773 6.822   -35.711 1.00 38.63  ? 429 PHE A CG  1 
ATOM   7294 C CD1 . PHE E 5 97  ? -11.870 7.388   -35.085 1.00 40.54  ? 429 PHE A CD1 1 
ATOM   7295 C CD2 . PHE E 5 97  ? -9.519  7.011   -35.153 1.00 41.48  ? 429 PHE A CD2 1 
ATOM   7296 C CE1 . PHE E 5 97  ? -11.721 8.131   -33.928 1.00 43.61  ? 429 PHE A CE1 1 
ATOM   7297 C CE2 . PHE E 5 97  ? -9.363  7.753   -33.997 1.00 41.63  ? 429 PHE A CE2 1 
ATOM   7298 C CZ  . PHE E 5 97  ? -10.466 8.313   -33.384 1.00 43.08  ? 429 PHE A CZ  1 
ATOM   7299 N N   . THR E 5 98  ? -10.956 9.225   -37.825 1.00 44.25  ? 430 THR A N   1 
ATOM   7300 C CA  . THR E 5 98  ? -10.223 10.479  -37.716 1.00 40.43  ? 430 THR A CA  1 
ATOM   7301 C C   . THR E 5 98  ? -10.402 11.027  -36.312 1.00 41.67  ? 430 THR A C   1 
ATOM   7302 O O   . THR E 5 98  ? -11.532 11.253  -35.866 1.00 34.14  ? 430 THR A O   1 
ATOM   7303 C CB  . THR E 5 98  ? -10.691 11.496  -38.755 1.00 37.77  ? 430 THR A CB  1 
ATOM   7304 O OG1 . THR E 5 98  ? -12.123 11.555  -38.762 1.00 60.21  ? 430 THR A OG1 1 
ATOM   7305 C CG2 . THR E 5 98  ? -10.195 11.089  -40.114 1.00 41.97  ? 430 THR A CG2 1 
ATOM   7306 N N   . GLY E 5 99  ? -9.294  11.244  -35.631 1.00 39.92  ? 431 GLY A N   1 
ATOM   7307 C CA  . GLY E 5 99  ? -9.313  11.668  -34.252 1.00 41.87  ? 431 GLY A CA  1 
ATOM   7308 C C   . GLY E 5 99  ? -8.135  11.061  -33.521 1.00 40.62  ? 431 GLY A C   1 
ATOM   7309 O O   . GLY E 5 99  ? -7.256  10.450  -34.121 1.00 34.25  ? 431 GLY A O   1 
ATOM   7310 N N   . CYS E 5 100 ? -8.144  11.238  -32.205 1.00 34.94  ? 432 CYS A N   1 
ATOM   7311 C CA  . CYS E 5 100 ? -7.064  10.775  -31.350 1.00 34.49  ? 432 CYS A CA  1 
ATOM   7312 C C   . CYS E 5 100 ? -7.617  9.846   -30.282 1.00 26.97  ? 432 CYS A C   1 
ATOM   7313 O O   . CYS E 5 100 ? -8.674  10.111  -29.701 1.00 37.85  ? 432 CYS A O   1 
ATOM   7314 C CB  . CYS E 5 100 ? -6.338  11.952  -30.691 1.00 50.35  ? 432 CYS A CB  1 
ATOM   7315 S SG  . CYS E 5 100 ? -5.758  13.230  -31.837 1.00 45.66  ? 432 CYS A SG  1 
ATOM   7316 N N   . VAL E 5 101 ? -6.902  8.753   -30.035 1.00 26.33  ? 433 VAL A N   1 
ATOM   7317 C CA  . VAL E 5 101 ? -7.173  7.872   -28.907 1.00 40.08  ? 433 VAL A CA  1 
ATOM   7318 C C   . VAL E 5 101 ? -6.120  8.148   -27.844 1.00 35.82  ? 433 VAL A C   1 
ATOM   7319 O O   . VAL E 5 101 ? -4.917  8.176   -28.138 1.00 35.22  ? 433 VAL A O   1 
ATOM   7320 C CB  . VAL E 5 101 ? -7.186  6.391   -29.335 1.00 24.68  ? 433 VAL A CB  1 
ATOM   7321 C CG1 . VAL E 5 101 ? -6.618  6.233   -30.736 1.00 33.06  ? 433 VAL A CG1 1 
ATOM   7322 C CG2 . VAL E 5 101 ? -6.434  5.514   -28.335 1.00 25.30  ? 433 VAL A CG2 1 
ATOM   7323 N N   . ILE E 5 102 ? -6.573  8.394   -26.618 1.00 33.65  ? 434 ILE A N   1 
ATOM   7324 C CA  . ILE E 5 102 ? -5.719  8.823   -25.517 1.00 24.71  ? 434 ILE A CA  1 
ATOM   7325 C C   . ILE E 5 102 ? -5.902  7.848   -24.365 1.00 30.48  ? 434 ILE A C   1 
ATOM   7326 O O   . ILE E 5 102 ? -7.036  7.531   -23.991 1.00 36.45  ? 434 ILE A O   1 
ATOM   7327 C CB  . ILE E 5 102 ? -6.054  10.259  -25.076 1.00 30.34  ? 434 ILE A CB  1 
ATOM   7328 C CG1 . ILE E 5 102 ? -5.913  11.225  -26.254 1.00 32.17  ? 434 ILE A CG1 1 
ATOM   7329 C CG2 . ILE E 5 102 ? -5.169  10.682  -23.914 1.00 32.83  ? 434 ILE A CG2 1 
ATOM   7330 C CD1 . ILE E 5 102 ? -6.637  12.536  -26.056 1.00 32.72  ? 434 ILE A CD1 1 
ATOM   7331 N N   . ALA E 5 103 ? -4.790  7.373   -23.809 1.00 36.06  ? 435 ALA A N   1 
ATOM   7332 C CA  . ALA E 5 103 ? -4.828  6.448   -22.687 1.00 42.11  ? 435 ALA A CA  1 
ATOM   7333 C C   . ALA E 5 103 ? -3.775  6.845   -21.663 1.00 47.40  ? 435 ALA A C   1 
ATOM   7334 O O   . ALA E 5 103 ? -2.759  7.461   -21.998 1.00 43.44  ? 435 ALA A O   1 
ATOM   7335 C CB  . ALA E 5 103 ? -4.601  4.998   -23.137 1.00 26.81  ? 435 ALA A CB  1 
ATOM   7336 N N   . TRP E 5 104 ? -4.036  6.491   -20.407 1.00 34.14  ? 436 TRP A N   1 
ATOM   7337 C CA  . TRP E 5 104 ? -3.081  6.703   -19.331 1.00 38.50  ? 436 TRP A CA  1 
ATOM   7338 C C   . TRP E 5 104 ? -3.328  5.663   -18.250 1.00 35.67  ? 436 TRP A C   1 
ATOM   7339 O O   . TRP E 5 104 ? -4.455  5.194   -18.068 1.00 32.84  ? 436 TRP A O   1 
ATOM   7340 C CB  . TRP E 5 104 ? -3.184  8.117   -18.746 1.00 50.15  ? 436 TRP A CB  1 
ATOM   7341 C CG  . TRP E 5 104 ? -4.508  8.419   -18.113 1.00 46.11  ? 436 TRP A CG  1 
ATOM   7342 C CD1 . TRP E 5 104 ? -4.869  8.187   -16.817 1.00 37.12  ? 436 TRP A CD1 1 
ATOM   7343 C CD2 . TRP E 5 104 ? -5.646  9.018   -18.745 1.00 42.20  ? 436 TRP A CD2 1 
ATOM   7344 N NE1 . TRP E 5 104 ? -6.162  8.600   -16.605 1.00 32.67  ? 436 TRP A NE1 1 
ATOM   7345 C CE2 . TRP E 5 104 ? -6.661  9.115   -17.773 1.00 30.18  ? 436 TRP A CE2 1 
ATOM   7346 C CE3 . TRP E 5 104 ? -5.905  9.480   -20.039 1.00 41.33  ? 436 TRP A CE3 1 
ATOM   7347 C CZ2 . TRP E 5 104 ? -7.915  9.654   -18.054 1.00 32.88  ? 436 TRP A CZ2 1 
ATOM   7348 C CZ3 . TRP E 5 104 ? -7.150  10.016  -20.316 1.00 37.47  ? 436 TRP A CZ3 1 
ATOM   7349 C CH2 . TRP E 5 104 ? -8.139  10.098  -19.328 1.00 37.83  ? 436 TRP A CH2 1 
ATOM   7350 N N   . ASN E 5 105 ? -2.262  5.305   -17.539 1.00 32.87  ? 437 ASN A N   1 
ATOM   7351 C CA  . ASN E 5 105 ? -2.373  4.321   -16.473 1.00 32.96  ? 437 ASN A CA  1 
ATOM   7352 C C   . ASN E 5 105 ? -3.223  4.874   -15.336 1.00 46.02  ? 437 ASN A C   1 
ATOM   7353 O O   . ASN E 5 105 ? -3.005  5.998   -14.873 1.00 54.92  ? 437 ASN A O   1 
ATOM   7354 C CB  . ASN E 5 105 ? -0.985  3.936   -15.962 1.00 26.98  ? 437 ASN A CB  1 
ATOM   7355 C CG  . ASN E 5 105 ? -1.034  2.862   -14.894 1.00 34.46  ? 437 ASN A CG  1 
ATOM   7356 O OD1 . ASN E 5 105 ? -1.297  3.144   -13.725 1.00 53.50  ? 437 ASN A OD1 1 
ATOM   7357 N ND2 . ASN E 5 105 ? -0.773  1.623   -15.290 1.00 28.72  ? 437 ASN A ND2 1 
ATOM   7358 N N   . SER E 5 106 ? -4.191  4.082   -14.887 1.00 39.20  ? 438 SER A N   1 
ATOM   7359 C CA  . SER E 5 106 ? -5.086  4.463   -13.801 1.00 54.00  ? 438 SER A CA  1 
ATOM   7360 C C   . SER E 5 106 ? -5.126  3.379   -12.737 1.00 56.81  ? 438 SER A C   1 
ATOM   7361 O O   . SER E 5 106 ? -6.185  3.049   -12.196 1.00 58.48  ? 438 SER A O   1 
ATOM   7362 C CB  . SER E 5 106 ? -6.490  4.754   -14.324 1.00 43.31  ? 438 SER A CB  1 
ATOM   7363 O OG  . SER E 5 106 ? -7.088  3.585   -14.855 1.00 53.38  ? 438 SER A OG  1 
ATOM   7364 N N   . ASN E 5 107 ? -3.963  2.799   -12.430 1.00 50.85  ? 439 ASN A N   1 
ATOM   7365 C CA  . ASN E 5 107 ? -3.894  1.791   -11.378 1.00 55.91  ? 439 ASN A CA  1 
ATOM   7366 C C   . ASN E 5 107 ? -4.273  2.386   -10.028 1.00 66.18  ? 439 ASN A C   1 
ATOM   7367 O O   . ASN E 5 107 ? -4.990  1.758   -9.241  1.00 69.28  ? 439 ASN A O   1 
ATOM   7368 C CB  . ASN E 5 107 ? -2.488  1.189   -11.325 1.00 42.51  ? 439 ASN A CB  1 
ATOM   7369 C CG  . ASN E 5 107 ? -2.425  -0.089  -10.506 1.00 52.75  ? 439 ASN A CG  1 
ATOM   7370 O OD1 . ASN E 5 107 ? -3.390  -0.469  -9.848  1.00 55.95  ? 439 ASN A OD1 1 
ATOM   7371 N ND2 . ASN E 5 107 ? -1.277  -0.753  -10.538 1.00 67.84  ? 439 ASN A ND2 1 
ATOM   7372 N N   . ASN E 5 108 ? -3.809  3.606   -9.748  1.00 65.35  ? 440 ASN A N   1 
ATOM   7373 C CA  . ASN E 5 108 ? -4.062  4.225   -8.454  1.00 66.29  ? 440 ASN A CA  1 
ATOM   7374 C C   . ASN E 5 108 ? -5.538  4.517   -8.219  1.00 64.17  ? 440 ASN A C   1 
ATOM   7375 O O   . ASN E 5 108 ? -5.955  4.639   -7.062  1.00 59.77  ? 440 ASN A O   1 
ATOM   7376 C CB  . ASN E 5 108 ? -3.252  5.515   -8.329  1.00 72.86  ? 440 ASN A CB  1 
ATOM   7377 C CG  . ASN E 5 108 ? -3.427  6.428   -9.526  1.00 75.43  ? 440 ASN A CG  1 
ATOM   7378 O OD1 . ASN E 5 108 ? -3.684  5.967   -10.638 1.00 68.81  ? 440 ASN A OD1 1 
ATOM   7379 N ND2 . ASN E 5 108 ? -3.285  7.730   -9.304  1.00 73.73  ? 440 ASN A ND2 1 
ATOM   7380 N N   . LEU E 5 109 ? -6.339  4.626   -9.276  1.00 66.38  ? 441 LEU A N   1 
ATOM   7381 C CA  . LEU E 5 109 ? -7.738  5.016   -9.144  1.00 61.39  ? 441 LEU A CA  1 
ATOM   7382 C C   . LEU E 5 109 ? -8.720  3.873   -9.348  1.00 59.59  ? 441 LEU A C   1 
ATOM   7383 O O   . LEU E 5 109 ? -9.711  3.783   -8.619  1.00 60.08  ? 441 LEU A O   1 
ATOM   7384 C CB  . LEU E 5 109 ? -8.074  6.139   -10.134 1.00 54.04  ? 441 LEU A CB  1 
ATOM   7385 C CG  . LEU E 5 109 ? -7.309  7.468   -10.087 1.00 69.64  ? 441 LEU A CG  1 
ATOM   7386 C CD1 . LEU E 5 109 ? -8.221  8.613   -10.516 1.00 53.82  ? 441 LEU A CD1 1 
ATOM   7387 C CD2 . LEU E 5 109 ? -6.706  7.752   -8.718  1.00 67.32  ? 441 LEU A CD2 1 
ATOM   7388 N N   . ASP E 5 110 ? -8.482  2.996   -10.323 1.00 63.95  ? 442 ASP A N   1 
ATOM   7389 C CA  . ASP E 5 110 ? -9.453  1.983   -10.713 1.00 64.59  ? 442 ASP A CA  1 
ATOM   7390 C C   . ASP E 5 110 ? -9.132  0.595   -10.173 1.00 64.67  ? 442 ASP A C   1 
ATOM   7391 O O   . ASP E 5 110 ? -9.825  -0.367  -10.521 1.00 68.51  ? 442 ASP A O   1 
ATOM   7392 C CB  . ASP E 5 110 ? -9.571  1.932   -12.237 1.00 55.10  ? 442 ASP A CB  1 
ATOM   7393 C CG  . ASP E 5 110 ? -10.183 3.190   -12.814 1.00 52.54  ? 442 ASP A CG  1 
ATOM   7394 O OD1 . ASP E 5 110 ? -11.179 3.682   -12.242 1.00 58.07  ? 442 ASP A OD1 1 
ATOM   7395 O OD2 . ASP E 5 110 ? -9.667  3.691   -13.835 1.00 46.18  ? 442 ASP A OD2 1 
ATOM   7396 N N   . SER E 5 111 ? -8.107  0.461   -9.336  1.00 59.27  ? 443 SER A N   1 
ATOM   7397 C CA  . SER E 5 111 ? -7.745  -0.822  -8.752  1.00 72.21  ? 443 SER A CA  1 
ATOM   7398 C C   . SER E 5 111 ? -7.910  -0.756  -7.242  1.00 73.22  ? 443 SER A C   1 
ATOM   7399 O O   . SER E 5 111 ? -7.407  0.170   -6.596  1.00 69.70  ? 443 SER A O   1 
ATOM   7400 C CB  . SER E 5 111 ? -6.310  -1.215  -9.109  1.00 69.99  ? 443 SER A CB  1 
ATOM   7401 O OG  . SER E 5 111 ? -5.376  -0.316  -8.538  1.00 71.32  ? 443 SER A OG  1 
ATOM   7402 N N   . LYS E 5 112 ? -8.614  -1.736  -6.687  1.00 72.77  ? 444 LYS A N   1 
ATOM   7403 C CA  . LYS E 5 112 ? -8.822  -1.850  -5.254  1.00 75.08  ? 444 LYS A CA  1 
ATOM   7404 C C   . LYS E 5 112 ? -8.162  -3.128  -4.755  1.00 79.16  ? 444 LYS A C   1 
ATOM   7405 O O   . LYS E 5 112 ? -8.057  -4.115  -5.489  1.00 83.71  ? 444 LYS A O   1 
ATOM   7406 C CB  . LYS E 5 112 ? -10.317 -1.850  -4.909  1.00 75.22  ? 444 LYS A CB  1 
ATOM   7407 C CG  . LYS E 5 112 ? -11.094 -0.718  -5.567  1.00 80.06  ? 444 LYS A CG  1 
ATOM   7408 C CD  . LYS E 5 112 ? -12.508 -0.608  -5.021  1.00 79.30  ? 444 LYS A CD  1 
ATOM   7409 C CE  . LYS E 5 112 ? -13.270 0.523   -5.698  1.00 66.46  ? 444 LYS A CE  1 
ATOM   7410 N NZ  . LYS E 5 112 ? -12.542 1.820   -5.602  1.00 59.22  ? 444 LYS A NZ  1 
ATOM   7411 N N   . VAL E 5 113 ? -7.699  -3.096  -3.503  1.00 81.18  ? 445 VAL A N   1 
ATOM   7412 C CA  . VAL E 5 113 ? -7.058  -4.270  -2.925  1.00 82.56  ? 445 VAL A CA  1 
ATOM   7413 C C   . VAL E 5 113 ? -8.064  -5.407  -2.849  1.00 82.77  ? 445 VAL A C   1 
ATOM   7414 O O   . VAL E 5 113 ? -9.168  -5.253  -2.311  1.00 82.11  ? 445 VAL A O   1 
ATOM   7415 C CB  . VAL E 5 113 ? -6.464  -3.938  -1.548  1.00 81.49  ? 445 VAL A CB  1 
ATOM   7416 C CG1 . VAL E 5 113 ? -5.130  -3.227  -1.709  1.00 60.06  ? 445 VAL A CG1 1 
ATOM   7417 C CG2 . VAL E 5 113 ? -7.430  -3.080  -0.745  1.00 91.28  ? 445 VAL A CG2 1 
ATOM   7418 N N   . GLY E 5 114 ? -7.684  -6.559  -3.397  1.00 76.23  ? 446 GLY A N   1 
ATOM   7419 C CA  . GLY E 5 114 ? -8.591  -7.664  -3.582  1.00 75.69  ? 446 GLY A CA  1 
ATOM   7420 C C   . GLY E 5 114 ? -9.263  -7.703  -4.937  1.00 86.21  ? 446 GLY A C   1 
ATOM   7421 O O   . GLY E 5 114 ? -9.768  -8.760  -5.332  1.00 83.01  ? 446 GLY A O   1 
ATOM   7422 N N   . GLY E 5 115 ? -9.276  -6.587  -5.661  1.00 84.95  ? 447 GLY A N   1 
ATOM   7423 C CA  . GLY E 5 115 ? -9.836  -6.512  -7.011  1.00 82.07  ? 447 GLY A CA  1 
ATOM   7424 C C   . GLY E 5 115 ? -11.038 -5.590  -7.075  1.00 78.76  ? 447 GLY A C   1 
ATOM   7425 O O   . GLY E 5 115 ? -11.945 -5.643  -6.244  1.00 88.22  ? 447 GLY A O   1 
ATOM   7426 N N   . ASN E 5 116 ? -11.040 -4.720  -8.088  1.00 77.35  ? 448 ASN A N   1 
ATOM   7427 C CA  . ASN E 5 116 ? -12.167 -3.811  -8.278  1.00 79.63  ? 448 ASN A CA  1 
ATOM   7428 C C   . ASN E 5 116 ? -13.418 -4.572  -8.700  1.00 75.85  ? 448 ASN A C   1 
ATOM   7429 O O   . ASN E 5 116 ? -14.498 -4.376  -8.130  1.00 93.58  ? 448 ASN A O   1 
ATOM   7430 C CB  . ASN E 5 116 ? -11.805 -2.741  -9.310  1.00 69.03  ? 448 ASN A CB  1 
ATOM   7431 C CG  . ASN E 5 116 ? -12.862 -1.660  -9.431  1.00 70.95  ? 448 ASN A CG  1 
ATOM   7432 O OD1 . ASN E 5 116 ? -13.806 -1.602  -8.642  1.00 60.72  ? 448 ASN A OD1 1 
ATOM   7433 N ND2 . ASN E 5 116 ? -12.702 -0.787  -10.419 1.00 70.70  ? 448 ASN A ND2 1 
ATOM   7434 N N   . TYR E 5 117 ? -13.288 -5.444  -9.702  1.00 53.96  ? 449 TYR A N   1 
ATOM   7435 C CA  . TYR E 5 117 ? -14.365 -6.305  -10.192 1.00 61.54  ? 449 TYR A CA  1 
ATOM   7436 C C   . TYR E 5 117 ? -15.620 -5.528  -10.579 1.00 61.68  ? 449 TYR A C   1 
ATOM   7437 O O   . TYR E 5 117 ? -16.718 -6.095  -10.607 1.00 61.19  ? 449 TYR A O   1 
ATOM   7438 C CB  . TYR E 5 117 ? -14.717 -7.394  -9.171  1.00 69.87  ? 449 TYR A CB  1 
ATOM   7439 C CG  . TYR E 5 117 ? -13.601 -8.380  -8.910  1.00 84.11  ? 449 TYR A CG  1 
ATOM   7440 C CD1 . TYR E 5 117 ? -13.287 -9.369  -9.834  1.00 80.38  ? 449 TYR A CD1 1 
ATOM   7441 C CD2 . TYR E 5 117 ? -12.866 -8.326  -7.734  1.00 89.97  ? 449 TYR A CD2 1 
ATOM   7442 C CE1 . TYR E 5 117 ? -12.266 -10.272 -9.596  1.00 88.30  ? 449 TYR A CE1 1 
ATOM   7443 C CE2 . TYR E 5 117 ? -11.848 -9.223  -7.486  1.00 85.56  ? 449 TYR A CE2 1 
ATOM   7444 C CZ  . TYR E 5 117 ? -11.550 -10.193 -8.418  1.00 93.91  ? 449 TYR A CZ  1 
ATOM   7445 O OH  . TYR E 5 117 ? -10.532 -11.085 -8.168  1.00 81.87  ? 449 TYR A OH  1 
ATOM   7446 N N   . ASN E 5 118 ? -15.485 -4.237  -10.882 1.00 65.56  ? 450 ASN A N   1 
ATOM   7447 C CA  . ASN E 5 118 ? -16.603 -3.421  -11.336 1.00 66.34  ? 450 ASN A CA  1 
ATOM   7448 C C   . ASN E 5 118 ? -16.555 -3.104  -12.821 1.00 61.62  ? 450 ASN A C   1 
ATOM   7449 O O   . ASN E 5 118 ? -17.607 -2.894  -13.428 1.00 50.47  ? 450 ASN A O   1 
ATOM   7450 C CB  . ASN E 5 118 ? -16.657 -2.102  -10.553 1.00 67.46  ? 450 ASN A CB  1 
ATOM   7451 C CG  . ASN E 5 118 ? -16.975 -2.308  -9.086  1.00 73.15  ? 450 ASN A CG  1 
ATOM   7452 O OD1 . ASN E 5 118 ? -17.719 -3.219  -8.721  1.00 72.06  ? 450 ASN A OD1 1 
ATOM   7453 N ND2 . ASN E 5 118 ? -16.411 -1.460  -8.233  1.00 67.79  ? 450 ASN A ND2 1 
ATOM   7454 N N   . TYR E 5 119 ? -15.365 -3.065  -13.415 1.00 60.54  ? 451 TYR A N   1 
ATOM   7455 C CA  . TYR E 5 119 ? -15.237 -2.832  -14.845 1.00 40.57  ? 451 TYR A CA  1 
ATOM   7456 C C   . TYR E 5 119 ? -15.412 -4.143  -15.596 1.00 40.09  ? 451 TYR A C   1 
ATOM   7457 O O   . TYR E 5 119 ? -14.795 -5.157  -15.252 1.00 31.90  ? 451 TYR A O   1 
ATOM   7458 C CB  . TYR E 5 119 ? -13.883 -2.202  -15.166 1.00 44.93  ? 451 TYR A CB  1 
ATOM   7459 C CG  . TYR E 5 119 ? -13.788 -0.754  -14.746 1.00 46.60  ? 451 TYR A CG  1 
ATOM   7460 C CD1 . TYR E 5 119 ? -14.454 0.237   -15.456 1.00 50.98  ? 451 TYR A CD1 1 
ATOM   7461 C CD2 . TYR E 5 119 ? -13.039 -0.377  -13.639 1.00 37.20  ? 451 TYR A CD2 1 
ATOM   7462 C CE1 . TYR E 5 119 ? -14.375 1.563   -15.077 1.00 48.67  ? 451 TYR A CE1 1 
ATOM   7463 C CE2 . TYR E 5 119 ? -12.955 0.948   -13.252 1.00 44.73  ? 451 TYR A CE2 1 
ATOM   7464 C CZ  . TYR E 5 119 ? -13.625 1.913   -13.975 1.00 46.67  ? 451 TYR A CZ  1 
ATOM   7465 O OH  . TYR E 5 119 ? -13.544 3.233   -13.594 1.00 48.79  ? 451 TYR A OH  1 
ATOM   7466 N N   . LEU E 5 120 ? -16.257 -4.121  -16.621 1.00 45.04  ? 452 LEU A N   1 
ATOM   7467 C CA  . LEU E 5 120 ? -16.633 -5.318  -17.353 1.00 40.94  ? 452 LEU A CA  1 
ATOM   7468 C C   . LEU E 5 120 ? -16.308 -5.160  -18.832 1.00 45.65  ? 452 LEU A C   1 
ATOM   7469 O O   . LEU E 5 120 ? -16.128 -4.050  -19.341 1.00 47.81  ? 452 LEU A O   1 
ATOM   7470 C CB  . LEU E 5 120 ? -18.128 -5.623  -17.185 1.00 50.15  ? 452 LEU A CB  1 
ATOM   7471 C CG  . LEU E 5 120 ? -18.712 -5.492  -15.777 1.00 36.71  ? 452 LEU A CG  1 
ATOM   7472 C CD1 . LEU E 5 120 ? -20.208 -5.766  -15.793 1.00 25.25  ? 452 LEU A CD1 1 
ATOM   7473 C CD2 . LEU E 5 120 ? -18.003 -6.421  -14.806 1.00 35.67  ? 452 LEU A CD2 1 
ATOM   7474 N N   . TYR E 5 121 ? -16.229 -6.299  -19.513 1.00 39.71  ? 453 TYR A N   1 
ATOM   7475 C CA  . TYR E 5 121 ? -16.051 -6.351  -20.956 1.00 36.69  ? 453 TYR A CA  1 
ATOM   7476 C C   . TYR E 5 121 ? -16.818 -7.549  -21.491 1.00 41.84  ? 453 TYR A C   1 
ATOM   7477 O O   . TYR E 5 121 ? -16.849 -8.607  -20.856 1.00 39.10  ? 453 TYR A O   1 
ATOM   7478 C CB  . TYR E 5 121 ? -14.566 -6.440  -21.345 1.00 29.30  ? 453 TYR A CB  1 
ATOM   7479 C CG  . TYR E 5 121 ? -13.895 -7.756  -21.020 1.00 39.18  ? 453 TYR A CG  1 
ATOM   7480 C CD1 . TYR E 5 121 ? -13.842 -8.230  -19.715 1.00 49.12  ? 453 TYR A CD1 1 
ATOM   7481 C CD2 . TYR E 5 121 ? -13.292 -8.514  -22.017 1.00 43.46  ? 453 TYR A CD2 1 
ATOM   7482 C CE1 . TYR E 5 121 ? -13.226 -9.425  -19.414 1.00 41.83  ? 453 TYR A CE1 1 
ATOM   7483 C CE2 . TYR E 5 121 ? -12.670 -9.713  -21.724 1.00 55.64  ? 453 TYR A CE2 1 
ATOM   7484 C CZ  . TYR E 5 121 ? -12.642 -10.162 -20.420 1.00 46.64  ? 453 TYR A CZ  1 
ATOM   7485 O OH  . TYR E 5 121 ? -12.027 -11.352 -20.112 1.00 62.53  ? 453 TYR A OH  1 
ATOM   7486 N N   . ARG E 5 122 ? -17.450 -7.376  -22.648 1.00 40.10  ? 454 ARG A N   1 
ATOM   7487 C CA  . ARG E 5 122 ? -18.219 -8.462  -23.237 1.00 29.16  ? 454 ARG A CA  1 
ATOM   7488 C C   . ARG E 5 122 ? -17.278 -9.548  -23.741 1.00 33.45  ? 454 ARG A C   1 
ATOM   7489 O O   . ARG E 5 122 ? -16.336 -9.271  -24.490 1.00 38.08  ? 454 ARG A O   1 
ATOM   7490 C CB  . ARG E 5 122 ? -19.097 -7.944  -24.375 1.00 34.72  ? 454 ARG A CB  1 
ATOM   7491 C CG  . ARG E 5 122 ? -19.986 -9.011  -24.990 1.00 29.17  ? 454 ARG A CG  1 
ATOM   7492 C CD  . ARG E 5 122 ? -20.939 -8.425  -26.016 1.00 33.65  ? 454 ARG A CD  1 
ATOM   7493 N NE  . ARG E 5 122 ? -21.778 -7.379  -25.443 1.00 39.07  ? 454 ARG A NE  1 
ATOM   7494 C CZ  . ARG E 5 122 ? -22.888 -7.603  -24.753 1.00 29.72  ? 454 ARG A CZ  1 
ATOM   7495 N NH1 . ARG E 5 122 ? -23.321 -8.831  -24.519 1.00 34.85  ? 454 ARG A NH1 1 
ATOM   7496 N NH2 . ARG E 5 122 ? -23.580 -6.568  -24.284 1.00 35.76  ? 454 ARG A NH2 1 
ATOM   7497 N N   . LEU E 5 123 ? -17.533 -10.786 -23.326 1.00 33.04  ? 455 LEU A N   1 
ATOM   7498 C CA  . LEU E 5 123 ? -16.683 -11.910 -23.691 1.00 28.97  ? 455 LEU A CA  1 
ATOM   7499 C C   . LEU E 5 123 ? -17.235 -12.734 -24.845 1.00 38.57  ? 455 LEU A C   1 
ATOM   7500 O O   . LEU E 5 123 ? -16.452 -13.263 -25.641 1.00 46.13  ? 455 LEU A O   1 
ATOM   7501 C CB  . LEU E 5 123 ? -16.464 -12.823 -22.478 1.00 39.15  ? 455 LEU A CB  1 
ATOM   7502 C CG  . LEU E 5 123 ? -15.465 -13.970 -22.646 1.00 43.42  ? 455 LEU A CG  1 
ATOM   7503 C CD1 . LEU E 5 123 ? -14.136 -13.439 -23.145 1.00 39.91  ? 455 LEU A CD1 1 
ATOM   7504 C CD2 . LEU E 5 123 ? -15.281 -14.724 -21.338 1.00 24.58  ? 455 LEU A CD2 1 
ATOM   7505 N N   . PHE E 5 124 ? -18.555 -12.851 -24.963 1.00 37.81  ? 456 PHE A N   1 
ATOM   7506 C CA  . PHE E 5 124 ? -19.181 -13.669 -25.991 1.00 42.87  ? 456 PHE A CA  1 
ATOM   7507 C C   . PHE E 5 124 ? -20.106 -12.825 -26.857 1.00 32.08  ? 456 PHE A C   1 
ATOM   7508 O O   . PHE E 5 124 ? -20.865 -11.993 -26.347 1.00 36.11  ? 456 PHE A O   1 
ATOM   7509 C CB  . PHE E 5 124 ? -19.971 -14.826 -25.371 1.00 41.82  ? 456 PHE A CB  1 
ATOM   7510 C CG  . PHE E 5 124 ? -19.118 -15.815 -24.632 1.00 41.62  ? 456 PHE A CG  1 
ATOM   7511 C CD1 . PHE E 5 124 ? -18.404 -16.782 -25.319 1.00 41.26  ? 456 PHE A CD1 1 
ATOM   7512 C CD2 . PHE E 5 124 ? -19.036 -15.783 -23.250 1.00 44.42  ? 456 PHE A CD2 1 
ATOM   7513 C CE1 . PHE E 5 124 ? -17.619 -17.696 -24.642 1.00 43.14  ? 456 PHE A CE1 1 
ATOM   7514 C CE2 . PHE E 5 124 ? -18.254 -16.696 -22.567 1.00 51.14  ? 456 PHE A CE2 1 
ATOM   7515 C CZ  . PHE E 5 124 ? -17.545 -17.653 -23.264 1.00 44.30  ? 456 PHE A CZ  1 
ATOM   7516 N N   . ARG E 5 125 ? -20.035 -13.047 -28.168 1.00 27.41  ? 457 ARG A N   1 
ATOM   7517 C CA  . ARG E 5 125 ? -20.932 -12.404 -29.116 1.00 33.75  ? 457 ARG A CA  1 
ATOM   7518 C C   . ARG E 5 125 ? -20.917 -13.204 -30.412 1.00 39.25  ? 457 ARG A C   1 
ATOM   7519 O O   . ARG E 5 125 ? -19.879 -13.752 -30.793 1.00 40.52  ? 457 ARG A O   1 
ATOM   7520 C CB  . ARG E 5 125 ? -20.530 -10.947 -29.376 1.00 29.08  ? 457 ARG A CB  1 
ATOM   7521 C CG  . ARG E 5 125 ? -21.650 -10.097 -29.953 1.00 32.88  ? 457 ARG A CG  1 
ATOM   7522 C CD  . ARG E 5 125 ? -21.310 -8.617  -29.909 1.00 29.06  ? 457 ARG A CD  1 
ATOM   7523 N NE  . ARG E 5 125 ? -22.489 -7.788  -30.127 1.00 28.63  ? 457 ARG A NE  1 
ATOM   7524 C CZ  . ARG E 5 125 ? -22.933 -7.414  -31.319 1.00 30.53  ? 457 ARG A CZ  1 
ATOM   7525 N NH1 . ARG E 5 125 ? -22.309 -7.767  -32.431 1.00 43.61  ? 457 ARG A NH1 1 
ATOM   7526 N NH2 . ARG E 5 125 ? -24.028 -6.663  -31.397 1.00 23.76  ? 457 ARG A NH2 1 
ATOM   7527 N N   . LYS E 5 126 ? -22.075 -13.276 -31.074 1.00 30.92  ? 458 LYS A N   1 
ATOM   7528 C CA  . LYS E 5 126 ? -22.169 -14.032 -32.321 1.00 45.26  ? 458 LYS A CA  1 
ATOM   7529 C C   . LYS E 5 126 ? -21.377 -13.370 -33.441 1.00 46.96  ? 458 LYS A C   1 
ATOM   7530 O O   . LYS E 5 126 ? -20.740 -14.058 -34.248 1.00 37.72  ? 458 LYS A O   1 
ATOM   7531 C CB  . LYS E 5 126 ? -23.632 -14.189 -32.735 1.00 46.27  ? 458 LYS A CB  1 
ATOM   7532 C CG  . LYS E 5 126 ? -24.202 -15.579 -32.518 1.00 46.01  ? 458 LYS A CG  1 
ATOM   7533 C CD  . LYS E 5 126 ? -24.318 -15.894 -31.042 1.00 53.15  ? 458 LYS A CD  1 
ATOM   7534 C CE  . LYS E 5 126 ? -25.310 -17.016 -30.792 1.00 42.70  ? 458 LYS A CE  1 
ATOM   7535 N NZ  . LYS E 5 126 ? -25.782 -17.003 -29.381 1.00 46.32  ? 458 LYS A NZ  1 
ATOM   7536 N N   . SER E 5 127 ? -21.410 -12.041 -33.514 1.00 44.93  ? 459 SER A N   1 
ATOM   7537 C CA  . SER E 5 127 ? -20.788 -11.309 -34.606 1.00 38.61  ? 459 SER A CA  1 
ATOM   7538 C C   . SER E 5 127 ? -20.095 -10.070 -34.059 1.00 37.24  ? 459 SER A C   1 
ATOM   7539 O O   . SER E 5 127 ? -20.412 -9.582  -32.971 1.00 36.86  ? 459 SER A O   1 
ATOM   7540 C CB  . SER E 5 127 ? -21.817 -10.917 -35.674 1.00 46.23  ? 459 SER A CB  1 
ATOM   7541 O OG  . SER E 5 127 ? -22.899 -10.202 -35.100 1.00 55.89  ? 459 SER A OG  1 
ATOM   7542 N N   . ASN E 5 128 ? -19.137 -9.566  -34.832 1.00 39.23  ? 460 ASN A N   1 
ATOM   7543 C CA  . ASN E 5 128 ? -18.388 -8.384  -34.432 1.00 35.57  ? 460 ASN A CA  1 
ATOM   7544 C C   . ASN E 5 128 ? -19.280 -7.148  -34.426 1.00 41.83  ? 460 ASN A C   1 
ATOM   7545 O O   . ASN E 5 128 ? -20.251 -7.046  -35.180 1.00 40.96  ? 460 ASN A O   1 
ATOM   7546 C CB  . ASN E 5 128 ? -17.204 -8.155  -35.370 1.00 27.58  ? 460 ASN A CB  1 
ATOM   7547 C CG  . ASN E 5 128 ? -16.265 -9.340  -35.426 1.00 39.14  ? 460 ASN A CG  1 
ATOM   7548 O OD1 . ASN E 5 128 ? -16.212 -10.150 -34.500 1.00 45.61  ? 460 ASN A OD1 1 
ATOM   7549 N ND2 . ASN E 5 128 ? -15.514 -9.448  -36.517 1.00 40.86  ? 460 ASN A ND2 1 
ATOM   7550 N N   . LEU E 5 129 ? -18.940 -6.204  -33.552 1.00 40.36  ? 461 LEU A N   1 
ATOM   7551 C CA  . LEU E 5 129 ? -19.626 -4.921  -33.530 1.00 33.29  ? 461 LEU A CA  1 
ATOM   7552 C C   . LEU E 5 129 ? -19.275 -4.106  -34.767 1.00 34.17  ? 461 LEU A C   1 
ATOM   7553 O O   . LEU E 5 129 ? -18.141 -4.140  -35.253 1.00 47.50  ? 461 LEU A O   1 
ATOM   7554 C CB  . LEU E 5 129 ? -19.249 -4.131  -32.277 1.00 32.00  ? 461 LEU A CB  1 
ATOM   7555 C CG  . LEU E 5 129 ? -19.890 -4.501  -30.941 1.00 31.47  ? 461 LEU A CG  1 
ATOM   7556 C CD1 . LEU E 5 129 ? -19.370 -3.580  -29.852 1.00 26.74  ? 461 LEU A CD1 1 
ATOM   7557 C CD2 . LEU E 5 129 ? -21.400 -4.409  -31.033 1.00 33.06  ? 461 LEU A CD2 1 
ATOM   7558 N N   . LYS E 5 130 ? -20.258 -3.373  -35.280 1.00 42.21  ? 462 LYS A N   1 
ATOM   7559 C CA  . LYS E 5 130 ? -19.979 -2.361  -36.280 1.00 39.91  ? 462 LYS A CA  1 
ATOM   7560 C C   . LYS E 5 130 ? -19.298 -1.170  -35.608 1.00 36.16  ? 462 LYS A C   1 
ATOM   7561 O O   . LYS E 5 130 ? -19.395 -0.998  -34.391 1.00 34.52  ? 462 LYS A O   1 
ATOM   7562 C CB  . LYS E 5 130 ? -21.269 -1.929  -36.975 1.00 32.24  ? 462 LYS A CB  1 
ATOM   7563 C CG  . LYS E 5 130 ? -22.177 -3.088  -37.365 1.00 40.43  ? 462 LYS A CG  1 
ATOM   7564 C CD  . LYS E 5 130 ? -22.788 -2.887  -38.744 1.00 52.64  ? 462 LYS A CD  1 
ATOM   7565 C CE  . LYS E 5 130 ? -23.113 -1.423  -39.002 1.00 81.19  ? 462 LYS A CE  1 
ATOM   7566 N NZ  . LYS E 5 130 ? -24.238 -1.266  -39.965 1.00 62.53  ? 462 LYS A NZ  1 
ATOM   7567 N N   . PRO E 5 131 ? -18.575 -0.349  -36.373 1.00 36.99  ? 463 PRO A N   1 
ATOM   7568 C CA  . PRO E 5 131 ? -17.879 0.791   -35.763 1.00 42.17  ? 463 PRO A CA  1 
ATOM   7569 C C   . PRO E 5 131 ? -18.839 1.715   -35.027 1.00 29.23  ? 463 PRO A C   1 
ATOM   7570 O O   . PRO E 5 131 ? -19.946 1.995   -35.494 1.00 22.94  ? 463 PRO A O   1 
ATOM   7571 C CB  . PRO E 5 131 ? -17.232 1.492   -36.962 1.00 42.63  ? 463 PRO A CB  1 
ATOM   7572 C CG  . PRO E 5 131 ? -17.036 0.404   -37.958 1.00 44.40  ? 463 PRO A CG  1 
ATOM   7573 C CD  . PRO E 5 131 ? -18.217 -0.514  -37.794 1.00 34.27  ? 463 PRO A CD  1 
ATOM   7574 N N   . PHE E 5 132 ? -18.393 2.187   -33.860 1.00 28.34  ? 464 PHE A N   1 
ATOM   7575 C CA  . PHE E 5 132 ? -19.175 3.085   -33.010 1.00 26.42  ? 464 PHE A CA  1 
ATOM   7576 C C   . PHE E 5 132 ? -20.542 2.490   -32.673 1.00 27.50  ? 464 PHE A C   1 
ATOM   7577 O O   . PHE E 5 132 ? -21.571 3.165   -32.735 1.00 34.13  ? 464 PHE A O   1 
ATOM   7578 C CB  . PHE E 5 132 ? -19.324 4.463   -33.656 1.00 32.53  ? 464 PHE A CB  1 
ATOM   7579 C CG  . PHE E 5 132 ? -18.036 5.237   -33.742 1.00 38.37  ? 464 PHE A CG  1 
ATOM   7580 C CD1 . PHE E 5 132 ? -17.081 5.134   -32.744 1.00 39.71  ? 464 PHE A CD1 1 
ATOM   7581 C CD2 . PHE E 5 132 ? -17.779 6.062   -34.826 1.00 39.01  ? 464 PHE A CD2 1 
ATOM   7582 C CE1 . PHE E 5 132 ? -15.895 5.845   -32.822 1.00 35.35  ? 464 PHE A CE1 1 
ATOM   7583 C CE2 . PHE E 5 132 ? -16.596 6.773   -34.910 1.00 33.51  ? 464 PHE A CE2 1 
ATOM   7584 C CZ  . PHE E 5 132 ? -15.653 6.665   -33.907 1.00 29.76  ? 464 PHE A CZ  1 
ATOM   7585 N N   . GLU E 5 133 ? -20.553 1.208   -32.317 1.00 37.30  ? 465 GLU A N   1 
ATOM   7586 C CA  . GLU E 5 133 ? -21.754 0.533   -31.848 1.00 35.88  ? 465 GLU A CA  1 
ATOM   7587 C C   . GLU E 5 133 ? -21.559 0.099   -30.403 1.00 39.43  ? 465 GLU A C   1 
ATOM   7588 O O   . GLU E 5 133 ? -20.487 -0.391  -30.032 1.00 38.11  ? 465 GLU A O   1 
ATOM   7589 C CB  . GLU E 5 133 ? -22.099 -0.687  -32.712 1.00 36.44  ? 465 GLU A CB  1 
ATOM   7590 C CG  . GLU E 5 133 ? -23.360 -1.417  -32.264 1.00 42.34  ? 465 GLU A CG  1 
ATOM   7591 C CD  . GLU E 5 133 ? -23.640 -2.672  -33.072 1.00 44.91  ? 465 GLU A CD  1 
ATOM   7592 O OE1 . GLU E 5 133 ? -22.903 -2.933  -34.047 1.00 46.35  ? 465 GLU A OE1 1 
ATOM   7593 O OE2 . GLU E 5 133 ? -24.597 -3.399  -32.730 1.00 31.81  ? 465 GLU A OE2 1 
ATOM   7594 N N   . ARG E 5 134 ? -22.596 0.286   -29.591 1.00 35.79  ? 466 ARG A N   1 
ATOM   7595 C CA  . ARG E 5 134 ? -22.566 -0.061  -28.178 1.00 32.89  ? 466 ARG A CA  1 
ATOM   7596 C C   . ARG E 5 134 ? -23.625 -1.116  -27.897 1.00 40.14  ? 466 ARG A C   1 
ATOM   7597 O O   . ARG E 5 134 ? -24.800 -0.926  -28.230 1.00 45.15  ? 466 ARG A O   1 
ATOM   7598 C CB  . ARG E 5 134 ? -22.800 1.175   -27.305 1.00 37.03  ? 466 ARG A CB  1 
ATOM   7599 C CG  . ARG E 5 134 ? -22.583 0.936   -25.824 1.00 44.72  ? 466 ARG A CG  1 
ATOM   7600 C CD  . ARG E 5 134 ? -22.770 2.216   -25.026 1.00 48.76  ? 466 ARG A CD  1 
ATOM   7601 N NE  . ARG E 5 134 ? -24.043 2.246   -24.316 1.00 71.92  ? 466 ARG A NE  1 
ATOM   7602 C CZ  . ARG E 5 134 ? -24.399 3.198   -23.464 1.00 89.51  ? 466 ARG A CZ  1 
ATOM   7603 N NH1 . ARG E 5 134 ? -23.604 4.223   -23.201 1.00 82.02  ? 466 ARG A NH1 1 
ATOM   7604 N NH2 . ARG E 5 134 ? -25.581 3.118   -22.859 1.00 83.80  ? 466 ARG A NH2 1 
ATOM   7605 N N   . ASP E 5 135 ? -23.208 -2.221  -27.284 1.00 30.00  ? 467 ASP A N   1 
ATOM   7606 C CA  . ASP E 5 135 ? -24.096 -3.323  -26.937 1.00 32.19  ? 467 ASP A CA  1 
ATOM   7607 C C   . ASP E 5 135 ? -24.086 -3.498  -25.426 1.00 44.22  ? 467 ASP A C   1 
ATOM   7608 O O   . ASP E 5 135 ? -23.056 -3.860  -24.847 1.00 52.33  ? 467 ASP A O   1 
ATOM   7609 C CB  . ASP E 5 135 ? -23.666 -4.617  -27.635 1.00 36.67  ? 467 ASP A CB  1 
ATOM   7610 C CG  . ASP E 5 135 ? -24.631 -5.764  -27.391 1.00 41.36  ? 467 ASP A CG  1 
ATOM   7611 O OD1 . ASP E 5 135 ? -25.727 -5.522  -26.844 1.00 44.68  ? 467 ASP A OD1 1 
ATOM   7612 O OD2 . ASP E 5 135 ? -24.290 -6.913  -27.748 1.00 40.70  ? 467 ASP A OD2 1 
ATOM   7613 N N   . ILE E 5 136 ? -25.232 -3.251  -24.795 1.00 37.58  ? 468 ILE A N   1 
ATOM   7614 C CA  . ILE E 5 136 ? -25.384 -3.384  -23.352 1.00 42.82  ? 468 ILE A CA  1 
ATOM   7615 C C   . ILE E 5 136 ? -26.199 -4.616  -22.980 1.00 41.08  ? 468 ILE A C   1 
ATOM   7616 O O   . ILE E 5 136 ? -26.630 -4.744  -21.829 1.00 31.60  ? 468 ILE A O   1 
ATOM   7617 C CB  . ILE E 5 136 ? -26.003 -2.119  -22.735 1.00 32.78  ? 468 ILE A CB  1 
ATOM   7618 C CG1 . ILE E 5 136 ? -27.274 -1.726  -23.491 1.00 33.60  ? 468 ILE A CG1 1 
ATOM   7619 C CG2 . ILE E 5 136 ? -24.998 -0.976  -22.728 1.00 31.08  ? 468 ILE A CG2 1 
ATOM   7620 C CD1 . ILE E 5 136 ? -28.130 -0.718  -22.756 1.00 37.79  ? 468 ILE A CD1 1 
ATOM   7621 N N   . SER E 5 137 ? -26.422 -5.526  -23.926 1.00 39.88  ? 469 SER A N   1 
ATOM   7622 C CA  . SER E 5 137 ? -27.224 -6.711  -23.651 1.00 34.32  ? 469 SER A CA  1 
ATOM   7623 C C   . SER E 5 137 ? -26.563 -7.585  -22.593 1.00 37.88  ? 469 SER A C   1 
ATOM   7624 O O   . SER E 5 137 ? -25.346 -7.792  -22.600 1.00 44.86  ? 469 SER A O   1 
ATOM   7625 C CB  . SER E 5 137 ? -27.439 -7.515  -24.934 1.00 35.81  ? 469 SER A CB  1 
ATOM   7626 O OG  . SER E 5 137 ? -28.009 -8.781  -24.653 1.00 40.43  ? 469 SER A OG  1 
ATOM   7627 N N   . THR E 5 138 ? -27.380 -8.087  -21.666 1.00 40.55  ? 470 THR A N   1 
ATOM   7628 C CA  . THR E 5 138 ? -26.943 -9.038  -20.654 1.00 33.18  ? 470 THR A CA  1 
ATOM   7629 C C   . THR E 5 138 ? -27.630 -10.391 -20.810 1.00 41.27  ? 470 THR A C   1 
ATOM   7630 O O   . THR E 5 138 ? -27.594 -11.213 -19.888 1.00 43.30  ? 470 THR A O   1 
ATOM   7631 C CB  . THR E 5 138 ? -27.190 -8.478  -19.251 1.00 31.20  ? 470 THR A CB  1 
ATOM   7632 O OG1 . THR E 5 138 ? -28.563 -8.087  -19.121 1.00 30.48  ? 470 THR A OG1 1 
ATOM   7633 C CG2 . THR E 5 138 ? -26.295 -7.275  -18.991 1.00 39.94  ? 470 THR A CG2 1 
ATOM   7634 N N   . GLU E 5 139 ? -28.258 -10.631 -21.960 1.00 38.91  ? 471 GLU A N   1 
ATOM   7635 C CA  . GLU E 5 139 ? -28.946 -11.894 -22.192 1.00 35.90  ? 471 GLU A CA  1 
ATOM   7636 C C   . GLU E 5 139 ? -27.955 -13.049 -22.157 1.00 44.70  ? 471 GLU A C   1 
ATOM   7637 O O   . GLU E 5 139 ? -26.819 -12.928 -22.623 1.00 54.84  ? 471 GLU A O   1 
ATOM   7638 C CB  . GLU E 5 139 ? -29.674 -11.866 -23.535 1.00 44.46  ? 471 GLU A CB  1 
ATOM   7639 C CG  . GLU E 5 139 ? -30.543 -13.086 -23.793 1.00 62.18  ? 471 GLU A CG  1 
ATOM   7640 C CD  . GLU E 5 139 ? -30.959 -13.214 -25.245 1.00 77.59  ? 471 GLU A CD  1 
ATOM   7641 O OE1 . GLU E 5 139 ? -30.369 -12.517 -26.098 1.00 83.56  ? 471 GLU A OE1 1 
ATOM   7642 O OE2 . GLU E 5 139 ? -31.876 -14.013 -25.534 1.00 79.99  ? 471 GLU A OE2 1 
ATOM   7643 N N   . ILE E 5 140 ? -28.394 -14.176 -21.593 1.00 51.17  ? 472 ILE A N   1 
ATOM   7644 C CA  . ILE E 5 140 ? -27.525 -15.340 -21.476 1.00 39.78  ? 472 ILE A CA  1 
ATOM   7645 C C   . ILE E 5 140 ? -27.108 -15.804 -22.862 1.00 41.00  ? 472 ILE A C   1 
ATOM   7646 O O   . ILE E 5 140 ? -27.950 -16.051 -23.736 1.00 34.89  ? 472 ILE A O   1 
ATOM   7647 C CB  . ILE E 5 140 ? -28.230 -16.457 -20.694 1.00 50.40  ? 472 ILE A CB  1 
ATOM   7648 C CG1 . ILE E 5 140 ? -28.477 -16.020 -19.249 1.00 41.88  ? 472 ILE A CG1 1 
ATOM   7649 C CG2 . ILE E 5 140 ? -27.412 -17.736 -20.736 1.00 40.58  ? 472 ILE A CG2 1 
ATOM   7650 C CD1 . ILE E 5 140 ? -27.221 -15.609 -18.517 1.00 33.86  ? 472 ILE A CD1 1 
ATOM   7651 N N   . TYR E 5 141 ? -25.800 -15.918 -23.070 1.00 51.10  ? 473 TYR A N   1 
ATOM   7652 C CA  . TYR E 5 141 ? -25.265 -16.294 -24.371 1.00 43.41  ? 473 TYR A CA  1 
ATOM   7653 C C   . TYR E 5 141 ? -25.484 -17.783 -24.609 1.00 35.61  ? 473 TYR A C   1 
ATOM   7654 O O   . TYR E 5 141 ? -25.031 -18.619 -23.820 1.00 32.88  ? 473 TYR A O   1 
ATOM   7655 C CB  . TYR E 5 141 ? -23.781 -15.943 -24.441 1.00 35.70  ? 473 TYR A CB  1 
ATOM   7656 C CG  . TYR E 5 141 ? -23.156 -16.142 -25.800 1.00 35.32  ? 473 TYR A CG  1 
ATOM   7657 C CD1 . TYR E 5 141 ? -23.260 -15.167 -26.780 1.00 38.30  ? 473 TYR A CD1 1 
ATOM   7658 C CD2 . TYR E 5 141 ? -22.452 -17.300 -26.099 1.00 37.23  ? 473 TYR A CD2 1 
ATOM   7659 C CE1 . TYR E 5 141 ? -22.688 -15.340 -28.021 1.00 43.17  ? 473 TYR A CE1 1 
ATOM   7660 C CE2 . TYR E 5 141 ? -21.876 -17.484 -27.340 1.00 40.09  ? 473 TYR A CE2 1 
ATOM   7661 C CZ  . TYR E 5 141 ? -21.997 -16.500 -28.298 1.00 42.19  ? 473 TYR A CZ  1 
ATOM   7662 O OH  . TYR E 5 141 ? -21.426 -16.674 -29.537 1.00 46.75  ? 473 TYR A OH  1 
ATOM   7663 N N   . GLN E 5 142 ? -26.175 -18.114 -25.698 1.00 28.48  ? 474 GLN A N   1 
ATOM   7664 C CA  . GLN E 5 142 ? -26.526 -19.498 -26.011 1.00 32.92  ? 474 GLN A CA  1 
ATOM   7665 C C   . GLN E 5 142 ? -25.446 -20.082 -26.913 1.00 35.81  ? 474 GLN A C   1 
ATOM   7666 O O   . GLN E 5 142 ? -25.405 -19.806 -28.115 1.00 36.98  ? 474 GLN A O   1 
ATOM   7667 C CB  . GLN E 5 142 ? -27.899 -19.569 -26.668 1.00 36.92  ? 474 GLN A CB  1 
ATOM   7668 C CG  . GLN E 5 142 ? -28.299 -20.966 -27.106 1.00 46.71  ? 474 GLN A CG  1 
ATOM   7669 C CD  . GLN E 5 142 ? -29.654 -21.003 -27.782 1.00 44.96  ? 474 GLN A CD  1 
ATOM   7670 O OE1 . GLN E 5 142 ? -30.534 -20.196 -27.481 1.00 48.73  ? 474 GLN A OE1 1 
ATOM   7671 N NE2 . GLN E 5 142 ? -29.828 -21.941 -28.706 1.00 41.39  ? 474 GLN A NE2 1 
ATOM   7672 N N   . ALA E 5 143 ? -24.573 -20.903 -26.333 1.00 37.42  ? 475 ALA A N   1 
ATOM   7673 C CA  . ALA E 5 143 ? -23.479 -21.527 -27.063 1.00 26.27  ? 475 ALA A CA  1 
ATOM   7674 C C   . ALA E 5 143 ? -23.865 -22.858 -27.696 1.00 36.10  ? 475 ALA A C   1 
ATOM   7675 O O   . ALA E 5 143 ? -23.047 -23.449 -28.408 1.00 33.89  ? 475 ALA A O   1 
ATOM   7676 C CB  . ALA E 5 143 ? -22.276 -21.727 -26.137 1.00 21.56  ? 475 ALA A CB  1 
ATOM   7677 N N   . GLY E 5 144 ? -25.081 -23.341 -27.456 1.00 38.01  ? 476 GLY A N   1 
ATOM   7678 C CA  . GLY E 5 144 ? -25.520 -24.598 -28.027 1.00 29.61  ? 476 GLY A CA  1 
ATOM   7679 C C   . GLY E 5 144 ? -26.869 -24.489 -28.707 1.00 36.83  ? 476 GLY A C   1 
ATOM   7680 O O   . GLY E 5 144 ? -27.359 -23.382 -28.948 1.00 42.31  ? 476 GLY A O   1 
ATOM   7681 N N   . SER E 5 145 ? -27.477 -25.629 -29.028 1.00 31.64  ? 477 SER A N   1 
ATOM   7682 C CA  . SER E 5 145 ? -28.788 -25.643 -29.661 1.00 32.56  ? 477 SER A CA  1 
ATOM   7683 C C   . SER E 5 145 ? -29.934 -25.553 -28.662 1.00 41.53  ? 477 SER A C   1 
ATOM   7684 O O   . SER E 5 145 ? -31.060 -25.236 -29.062 1.00 45.50  ? 477 SER A O   1 
ATOM   7685 C CB  . SER E 5 145 ? -28.952 -26.913 -30.503 1.00 38.38  ? 477 SER A CB  1 
ATOM   7686 O OG  . SER E 5 145 ? -27.895 -27.043 -31.439 1.00 70.82  ? 477 SER A OG  1 
ATOM   7687 N N   . THR E 5 146 ? -29.675 -25.817 -27.387 1.00 49.83  ? 478 THR A N   1 
ATOM   7688 C CA  . THR E 5 146 ? -30.726 -25.787 -26.375 1.00 50.75  ? 478 THR A CA  1 
ATOM   7689 C C   . THR E 5 146 ? -30.954 -24.357 -25.897 1.00 56.17  ? 478 THR A C   1 
ATOM   7690 O O   . THR E 5 146 ? -29.997 -23.686 -25.496 1.00 53.42  ? 478 THR A O   1 
ATOM   7691 C CB  . THR E 5 146 ? -30.358 -26.676 -25.189 1.00 45.59  ? 478 THR A CB  1 
ATOM   7692 O OG1 . THR E 5 146 ? -30.139 -28.018 -25.643 1.00 44.54  ? 478 THR A OG1 1 
ATOM   7693 C CG2 . THR E 5 146 ? -31.474 -26.672 -24.152 1.00 43.80  ? 478 THR A CG2 1 
ATOM   7694 N N   . PRO E 5 147 ? -32.190 -23.858 -25.931 1.00 60.93  ? 479 PRO A N   1 
ATOM   7695 C CA  . PRO E 5 147 ? -32.464 -22.537 -25.355 1.00 56.45  ? 479 PRO A CA  1 
ATOM   7696 C C   . PRO E 5 147 ? -32.110 -22.501 -23.876 1.00 49.82  ? 479 PRO A C   1 
ATOM   7697 O O   . PRO E 5 147 ? -32.256 -23.489 -23.154 1.00 53.70  ? 479 PRO A O   1 
ATOM   7698 C CB  . PRO E 5 147 ? -33.971 -22.358 -25.576 1.00 58.42  ? 479 PRO A CB  1 
ATOM   7699 C CG  . PRO E 5 147 ? -34.289 -23.249 -26.734 1.00 61.38  ? 479 PRO A CG  1 
ATOM   7700 C CD  . PRO E 5 147 ? -33.373 -24.431 -26.596 1.00 47.28  ? 479 PRO A CD  1 
ATOM   7701 N N   . CYS E 5 148 ? -31.629 -21.340 -23.431 1.00 57.52  ? 480 CYS A N   1 
ATOM   7702 C CA  . CYS E 5 148 ? -31.157 -21.184 -22.061 1.00 55.23  ? 480 CYS A CA  1 
ATOM   7703 C C   . CYS E 5 148 ? -32.223 -20.667 -21.107 1.00 65.73  ? 480 CYS A C   1 
ATOM   7704 O O   . CYS E 5 148 ? -32.098 -20.877 -19.895 1.00 57.37  ? 480 CYS A O   1 
ATOM   7705 C CB  . CYS E 5 148 ? -29.950 -20.242 -22.026 1.00 53.62  ? 480 CYS A CB  1 
ATOM   7706 S SG  . CYS E 5 148 ? -28.548 -20.803 -23.019 1.00 88.75  ? 480 CYS A SG  1 
ATOM   7707 N N   . ASN E 5 149 ? -33.258 -19.995 -21.618 1.00 74.24  ? 481 ASN A N   1 
ATOM   7708 C CA  . ASN E 5 149 ? -34.330 -19.434 -20.792 1.00 67.03  ? 481 ASN A CA  1 
ATOM   7709 C C   . ASN E 5 149 ? -33.778 -18.491 -19.725 1.00 63.82  ? 481 ASN A C   1 
ATOM   7710 O O   . ASN E 5 149 ? -34.285 -18.427 -18.604 1.00 57.89  ? 481 ASN A O   1 
ATOM   7711 C CB  . ASN E 5 149 ? -35.176 -20.538 -20.152 1.00 58.67  ? 481 ASN A CB  1 
ATOM   7712 C CG  . ASN E 5 149 ? -35.775 -21.482 -21.174 1.00 73.96  ? 481 ASN A CG  1 
ATOM   7713 O OD1 . ASN E 5 149 ? -35.588 -22.697 -21.097 1.00 79.68  ? 481 ASN A OD1 1 
ATOM   7714 N ND2 . ASN E 5 149 ? -36.499 -20.928 -22.140 1.00 79.05  ? 481 ASN A ND2 1 
ATOM   7715 N N   . GLY E 5 150 ? -32.724 -17.756 -20.074 1.00 74.79  ? 482 GLY A N   1 
ATOM   7716 C CA  . GLY E 5 150 ? -32.165 -16.775 -19.165 1.00 71.51  ? 482 GLY A CA  1 
ATOM   7717 C C   . GLY E 5 150 ? -31.517 -17.336 -17.920 1.00 70.58  ? 482 GLY A C   1 
ATOM   7718 O O   . GLY E 5 150 ? -31.357 -16.605 -16.939 1.00 74.39  ? 482 GLY A O   1 
ATOM   7719 N N   . VAL E 5 151 ? -31.135 -18.611 -17.925 1.00 72.74  ? 483 VAL A N   1 
ATOM   7720 C CA  . VAL E 5 151 ? -30.467 -19.236 -16.791 1.00 66.05  ? 483 VAL A CA  1 
ATOM   7721 C C   . VAL E 5 151 ? -29.086 -19.694 -17.238 1.00 63.63  ? 483 VAL A C   1 
ATOM   7722 O O   . VAL E 5 151 ? -28.893 -20.094 -18.392 1.00 62.55  ? 483 VAL A O   1 
ATOM   7723 C CB  . VAL E 5 151 ? -31.287 -20.408 -16.204 1.00 61.31  ? 483 VAL A CB  1 
ATOM   7724 C CG1 . VAL E 5 151 ? -32.763 -20.035 -16.111 1.00 68.12  ? 483 VAL A CG1 1 
ATOM   7725 C CG2 . VAL E 5 151 ? -31.097 -21.688 -17.009 1.00 61.53  ? 483 VAL A CG2 1 
ATOM   7726 N N   . GLU E 5 152 ? -28.119 -19.601 -16.331 1.00 62.75  ? 484 GLU A N   1 
ATOM   7727 C CA  . GLU E 5 152 ? -26.741 -19.951 -16.634 1.00 50.73  ? 484 GLU A CA  1 
ATOM   7728 C C   . GLU E 5 152 ? -26.510 -21.439 -16.404 1.00 47.90  ? 484 GLU A C   1 
ATOM   7729 O O   . GLU E 5 152 ? -27.159 -22.069 -15.567 1.00 53.36  ? 484 GLU A O   1 
ATOM   7730 C CB  . GLU E 5 152 ? -25.778 -19.125 -15.777 1.00 47.39  ? 484 GLU A CB  1 
ATOM   7731 C CG  . GLU E 5 152 ? -24.339 -19.130 -16.266 1.00 60.54  ? 484 GLU A CG  1 
ATOM   7732 C CD  . GLU E 5 152 ? -23.517 -17.993 -15.684 1.00 88.08  ? 484 GLU A CD  1 
ATOM   7733 O OE1 . GLU E 5 152 ? -23.614 -17.743 -14.463 1.00 73.08  ? 484 GLU A OE1 1 
ATOM   7734 O OE2 . GLU E 5 152 ? -22.779 -17.343 -16.455 1.00 90.15  ? 484 GLU A OE2 1 
ATOM   7735 N N   . GLY E 5 153 ? -25.579 -21.998 -17.166 1.00 51.51  ? 485 GLY A N   1 
ATOM   7736 C CA  . GLY E 5 153 ? -25.264 -23.414 -17.050 1.00 41.87  ? 485 GLY A CA  1 
ATOM   7737 C C   . GLY E 5 153 ? -24.448 -23.881 -18.242 1.00 44.66  ? 485 GLY A C   1 
ATOM   7738 O O   . GLY E 5 153 ? -23.693 -23.108 -18.837 1.00 47.75  ? 485 GLY A O   1 
ATOM   7739 N N   . PHE E 5 154 ? -24.611 -25.160 -18.567 1.00 46.78  ? 486 PHE A N   1 
ATOM   7740 C CA  . PHE E 5 154 ? -23.896 -25.750 -19.695 1.00 46.20  ? 486 PHE A CA  1 
ATOM   7741 C C   . PHE E 5 154 ? -24.364 -25.137 -21.008 1.00 42.52  ? 486 PHE A C   1 
ATOM   7742 O O   . PHE E 5 154 ? -25.565 -24.971 -21.242 1.00 58.47  ? 486 PHE A O   1 
ATOM   7743 C CB  . PHE E 5 154 ? -24.103 -27.263 -19.710 1.00 45.96  ? 486 PHE A CB  1 
ATOM   7744 C CG  . PHE E 5 154 ? -23.551 -27.937 -20.935 1.00 51.71  ? 486 PHE A CG  1 
ATOM   7745 C CD1 . PHE E 5 154 ? -22.184 -28.024 -21.140 1.00 49.86  ? 486 PHE A CD1 1 
ATOM   7746 C CD2 . PHE E 5 154 ? -24.402 -28.496 -21.875 1.00 57.46  ? 486 PHE A CD2 1 
ATOM   7747 C CE1 . PHE E 5 154 ? -21.675 -28.648 -22.265 1.00 43.90  ? 486 PHE A CE1 1 
ATOM   7748 C CE2 . PHE E 5 154 ? -23.900 -29.122 -23.000 1.00 61.63  ? 486 PHE A CE2 1 
ATOM   7749 C CZ  . PHE E 5 154 ? -22.536 -29.197 -23.196 1.00 55.65  ? 486 PHE A CZ  1 
ATOM   7750 N N   . ASN E 5 155 ? -23.400 -24.801 -21.866 1.00 31.13  ? 487 ASN A N   1 
ATOM   7751 C CA  . ASN E 5 155 ? -23.638 -24.134 -23.149 1.00 40.27  ? 487 ASN A CA  1 
ATOM   7752 C C   . ASN E 5 155 ? -24.406 -22.824 -22.993 1.00 45.37  ? 487 ASN A C   1 
ATOM   7753 O O   . ASN E 5 155 ? -24.983 -22.320 -23.962 1.00 49.50  ? 487 ASN A O   1 
ATOM   7754 C CB  . ASN E 5 155 ? -24.370 -25.052 -24.136 1.00 37.62  ? 487 ASN A CB  1 
ATOM   7755 C CG  . ASN E 5 155 ? -23.447 -26.060 -24.791 1.00 40.91  ? 487 ASN A CG  1 
ATOM   7756 O OD1 . ASN E 5 155 ? -22.224 -25.943 -24.714 1.00 30.12  ? 487 ASN A OD1 1 
ATOM   7757 N ND2 . ASN E 5 155 ? -24.032 -27.051 -25.453 1.00 42.44  ? 487 ASN A ND2 1 
ATOM   7758 N N   . CYS E 5 156 ? -24.423 -22.258 -21.786 1.00 39.77  ? 488 CYS A N   1 
ATOM   7759 C CA  . CYS E 5 156 ? -25.166 -21.029 -21.503 1.00 40.55  ? 488 CYS A CA  1 
ATOM   7760 C C   . CYS E 5 156 ? -24.284 -20.155 -20.617 1.00 42.39  ? 488 CYS A C   1 
ATOM   7761 O O   . CYS E 5 156 ? -24.161 -20.403 -19.413 1.00 45.75  ? 488 CYS A O   1 
ATOM   7762 C CB  . CYS E 5 156 ? -26.503 -21.332 -20.838 1.00 35.44  ? 488 CYS A CB  1 
ATOM   7763 S SG  . CYS E 5 156 ? -27.666 -22.242 -21.884 1.00 42.98  ? 488 CYS A SG  1 
ATOM   7764 N N   . TYR E 5 157 ? -23.681 -19.132 -21.213 1.00 40.20  ? 489 TYR A N   1 
ATOM   7765 C CA  . TYR E 5 157 ? -22.712 -18.287 -20.536 1.00 46.46  ? 489 TYR A CA  1 
ATOM   7766 C C   . TYR E 5 157 ? -23.255 -16.872 -20.389 1.00 45.93  ? 489 TYR A C   1 
ATOM   7767 O O   . TYR E 5 157 ? -23.993 -16.380 -21.247 1.00 44.85  ? 489 TYR A O   1 
ATOM   7768 C CB  . TYR E 5 157 ? -21.388 -18.242 -21.308 1.00 50.69  ? 489 TYR A CB  1 
ATOM   7769 C CG  . TYR E 5 157 ? -20.894 -19.588 -21.794 1.00 43.35  ? 489 TYR A CG  1 
ATOM   7770 C CD1 . TYR E 5 157 ? -20.956 -20.712 -20.981 1.00 31.16  ? 489 TYR A CD1 1 
ATOM   7771 C CD2 . TYR E 5 157 ? -20.367 -19.733 -23.072 1.00 41.32  ? 489 TYR A CD2 1 
ATOM   7772 C CE1 . TYR E 5 157 ? -20.504 -21.942 -21.425 1.00 42.09  ? 489 TYR A CE1 1 
ATOM   7773 C CE2 . TYR E 5 157 ? -19.913 -20.957 -23.525 1.00 41.84  ? 489 TYR A CE2 1 
ATOM   7774 C CZ  . TYR E 5 157 ? -19.984 -22.058 -22.698 1.00 52.71  ? 489 TYR A CZ  1 
ATOM   7775 O OH  . TYR E 5 157 ? -19.533 -23.279 -23.147 1.00 54.01  ? 489 TYR A OH  1 
ATOM   7776 N N   . PHE E 5 158 ? -22.887 -16.226 -19.292 1.00 37.72  ? 490 PHE A N   1 
ATOM   7777 C CA  . PHE E 5 158 ? -23.159 -14.803 -19.142 1.00 42.10  ? 490 PHE A CA  1 
ATOM   7778 C C   . PHE E 5 158 ? -22.217 -14.036 -20.061 1.00 42.73  ? 490 PHE A C   1 
ATOM   7779 O O   . PHE E 5 158 ? -20.995 -14.217 -19.967 1.00 34.31  ? 490 PHE A O   1 
ATOM   7780 C CB  . PHE E 5 158 ? -22.978 -14.374 -17.687 1.00 47.36  ? 490 PHE A CB  1 
ATOM   7781 C CG  . PHE E 5 158 ? -23.440 -12.970 -17.403 1.00 67.55  ? 490 PHE A CG  1 
ATOM   7782 C CD1 . PHE E 5 158 ? -24.754 -12.597 -17.633 1.00 64.70  ? 490 PHE A CD1 1 
ATOM   7783 C CD2 . PHE E 5 158 ? -22.564 -12.031 -16.884 1.00 57.37  ? 490 PHE A CD2 1 
ATOM   7784 C CE1 . PHE E 5 158 ? -25.183 -11.309 -17.369 1.00 44.30  ? 490 PHE A CE1 1 
ATOM   7785 C CE2 . PHE E 5 158 ? -22.987 -10.743 -16.614 1.00 48.81  ? 490 PHE A CE2 1 
ATOM   7786 C CZ  . PHE E 5 158 ? -24.298 -10.381 -16.857 1.00 52.77  ? 490 PHE A CZ  1 
ATOM   7787 N N   . PRO E 5 159 ? -22.725 -13.187 -20.960 1.00 49.19  ? 491 PRO A N   1 
ATOM   7788 C CA  . PRO E 5 159 ? -21.846 -12.578 -21.973 1.00 43.89  ? 491 PRO A CA  1 
ATOM   7789 C C   . PRO E 5 159 ? -20.785 -11.660 -21.399 1.00 44.61  ? 491 PRO A C   1 
ATOM   7790 O O   . PRO E 5 159 ? -19.790 -11.390 -22.083 1.00 46.78  ? 491 PRO A O   1 
ATOM   7791 C CB  . PRO E 5 159 ? -22.826 -11.804 -22.864 1.00 51.30  ? 491 PRO A CB  1 
ATOM   7792 C CG  . PRO E 5 159 ? -23.961 -11.474 -21.953 1.00 42.77  ? 491 PRO A CG  1 
ATOM   7793 C CD  . PRO E 5 159 ? -24.096 -12.655 -21.029 1.00 44.26  ? 491 PRO A CD  1 
ATOM   7794 N N   . LEU E 5 160 ? -20.957 -11.174 -20.173 1.00 43.64  ? 492 LEU A N   1 
ATOM   7795 C CA  . LEU E 5 160 ? -20.056 -10.193 -19.588 1.00 37.82  ? 492 LEU A CA  1 
ATOM   7796 C C   . LEU E 5 160 ? -19.083 -10.868 -18.630 1.00 42.88  ? 492 LEU A C   1 
ATOM   7797 O O   . LEU E 5 160 ? -19.442 -11.814 -17.923 1.00 36.97  ? 492 LEU A O   1 
ATOM   7798 C CB  . LEU E 5 160 ? -20.841 -9.101  -18.858 1.00 25.47  ? 492 LEU A CB  1 
ATOM   7799 C CG  . LEU E 5 160 ? -21.302 -7.875  -19.655 1.00 28.25  ? 492 LEU A CG  1 
ATOM   7800 C CD1 . LEU E 5 160 ? -21.931 -8.254  -20.989 1.00 28.83  ? 492 LEU A CD1 1 
ATOM   7801 C CD2 . LEU E 5 160 ? -22.276 -7.051  -18.828 1.00 36.92  ? 492 LEU A CD2 1 
ATOM   7802 N N   . GLN E 5 161 ? -17.846 -10.377 -18.623 1.00 42.83  ? 493 GLN A N   1 
ATOM   7803 C CA  . GLN E 5 161 ? -16.796 -10.859 -17.740 1.00 27.39  ? 493 GLN A CA  1 
ATOM   7804 C C   . GLN E 5 161 ? -16.166 -9.662  -17.040 1.00 36.05  ? 493 GLN A C   1 
ATOM   7805 O O   . GLN E 5 161 ? -16.143 -8.553  -17.580 1.00 24.81  ? 493 GLN A O   1 
ATOM   7806 C CB  . GLN E 5 161 ? -15.737 -11.660 -18.524 1.00 34.61  ? 493 GLN A CB  1 
ATOM   7807 C CG  . GLN E 5 161 ? -14.563 -12.177 -17.700 1.00 49.42  ? 493 GLN A CG  1 
ATOM   7808 C CD  . GLN E 5 161 ? -14.904 -13.414 -16.895 1.00 44.58  ? 493 GLN A CD  1 
ATOM   7809 O OE1 . GLN E 5 161 ? -15.832 -14.151 -17.228 1.00 47.07  ? 493 GLN A OE1 1 
ATOM   7810 N NE2 . GLN E 5 161 ? -14.149 -13.649 -15.827 1.00 47.50  ? 493 GLN A NE2 1 
ATOM   7811 N N   . SER E 5 162 ? -15.664 -9.889  -15.830 1.00 44.52  ? 494 SER A N   1 
ATOM   7812 C CA  . SER E 5 162 ? -15.171 -8.818  -14.974 1.00 46.39  ? 494 SER A CA  1 
ATOM   7813 C C   . SER E 5 162 ? -13.648 -8.776  -14.989 1.00 43.08  ? 494 SER A C   1 
ATOM   7814 O O   . SER E 5 162 ? -12.991 -9.816  -14.875 1.00 45.66  ? 494 SER A O   1 
ATOM   7815 C CB  . SER E 5 162 ? -15.680 -8.998  -13.544 1.00 52.07  ? 494 SER A CB  1 
ATOM   7816 O OG  . SER E 5 162 ? -15.297 -7.907  -12.730 1.00 55.92  ? 494 SER A OG  1 
ATOM   7817 N N   . TYR E 5 163 ? -13.095 -7.572  -15.130 1.00 46.90  ? 495 TYR A N   1 
ATOM   7818 C CA  . TYR E 5 163 ? -11.652 -7.385  -15.067 1.00 39.58  ? 495 TYR A CA  1 
ATOM   7819 C C   . TYR E 5 163 ? -11.130 -7.679  -13.666 1.00 52.84  ? 495 TYR A C   1 
ATOM   7820 O O   . TYR E 5 163 ? -11.749 -7.310  -12.664 1.00 66.02  ? 495 TYR A O   1 
ATOM   7821 C CB  . TYR E 5 163 ? -11.283 -5.954  -15.461 1.00 43.75  ? 495 TYR A CB  1 
ATOM   7822 C CG  . TYR E 5 163 ? -11.269 -5.680  -16.949 1.00 40.76  ? 495 TYR A CG  1 
ATOM   7823 C CD1 . TYR E 5 163 ? -10.568 -6.502  -17.821 1.00 39.59  ? 495 TYR A CD1 1 
ATOM   7824 C CD2 . TYR E 5 163 ? -11.954 -4.595  -17.480 1.00 48.04  ? 495 TYR A CD2 1 
ATOM   7825 C CE1 . TYR E 5 163 ? -10.551 -6.251  -19.181 1.00 42.48  ? 495 TYR A CE1 1 
ATOM   7826 C CE2 . TYR E 5 163 ? -11.944 -4.337  -18.837 1.00 45.98  ? 495 TYR A CE2 1 
ATOM   7827 C CZ  . TYR E 5 163 ? -11.240 -5.167  -19.683 1.00 44.80  ? 495 TYR A CZ  1 
ATOM   7828 O OH  . TYR E 5 163 ? -11.228 -4.913  -21.035 1.00 47.22  ? 495 TYR A OH  1 
ATOM   7829 N N   . GLY E 5 164 ? -9.979  -8.343  -13.599 1.00 63.44  ? 496 GLY A N   1 
ATOM   7830 C CA  . GLY E 5 164 ? -9.333  -8.610  -12.328 1.00 81.18  ? 496 GLY A CA  1 
ATOM   7831 C C   . GLY E 5 164 ? -8.325  -7.546  -11.945 1.00 80.46  ? 496 GLY A C   1 
ATOM   7832 O O   . GLY E 5 164 ? -7.128  -7.828  -11.829 1.00 91.31  ? 496 GLY A O   1 
ATOM   7833 N N   . PHE E 5 165 ? -8.797  -6.319  -11.739 1.00 61.55  ? 497 PHE A N   1 
ATOM   7834 C CA  . PHE E 5 165 ? -7.920  -5.176  -11.488 1.00 57.51  ? 497 PHE A CA  1 
ATOM   7835 C C   . PHE E 5 165 ? -7.422  -5.221  -10.050 1.00 74.60  ? 497 PHE A C   1 
ATOM   7836 O O   . PHE E 5 165 ? -8.144  -4.871  -9.115  1.00 90.82  ? 497 PHE A O   1 
ATOM   7837 C CB  . PHE E 5 165 ? -8.650  -3.870  -11.778 1.00 66.62  ? 497 PHE A CB  1 
ATOM   7838 C CG  . PHE E 5 165 ? -8.840  -3.595  -13.241 1.00 57.65  ? 497 PHE A CG  1 
ATOM   7839 C CD1 . PHE E 5 165 ? -7.932  -4.076  -14.170 1.00 49.08  ? 497 PHE A CD1 1 
ATOM   7840 C CD2 . PHE E 5 165 ? -9.925  -2.861  -13.689 1.00 52.80  ? 497 PHE A CD2 1 
ATOM   7841 C CE1 . PHE E 5 165 ? -8.101  -3.828  -15.517 1.00 43.65  ? 497 PHE A CE1 1 
ATOM   7842 C CE2 . PHE E 5 165 ? -10.099 -2.609  -15.037 1.00 39.97  ? 497 PHE A CE2 1 
ATOM   7843 C CZ  . PHE E 5 165 ? -9.186  -3.093  -15.951 1.00 40.19  ? 497 PHE A CZ  1 
ATOM   7844 N N   . GLN E 5 166 ? -6.170  -5.641  -9.876  1.00 73.84  ? 498 GLN A N   1 
ATOM   7845 C CA  . GLN E 5 166 ? -5.487  -5.677  -8.598  1.00 71.98  ? 498 GLN A CA  1 
ATOM   7846 C C   . GLN E 5 166 ? -4.204  -4.859  -8.676  1.00 73.07  ? 498 GLN A C   1 
ATOM   7847 O O   . GLN E 5 166 ? -3.543  -4.847  -9.720  1.00 78.56  ? 498 GLN A O   1 
ATOM   7848 C CB  . GLN E 5 166 ? -5.151  -7.121  -8.194  1.00 78.49  ? 498 GLN A CB  1 
ATOM   7849 C CG  . GLN E 5 166 ? -6.355  -8.048  -8.119  1.00 82.69  ? 498 GLN A CG  1 
ATOM   7850 C CD  . GLN E 5 166 ? -5.974  -9.508  -8.282  1.00 89.33  ? 498 GLN A CD  1 
ATOM   7851 O OE1 . GLN E 5 166 ? -6.625  -10.398 -7.735  1.00 98.34  ? 498 GLN A OE1 1 
ATOM   7852 N NE2 . GLN E 5 166 ? -4.917  -9.760  -9.046  1.00 89.74  ? 498 GLN A NE2 1 
ATOM   7853 N N   . PRO E 5 167 ? -3.830  -4.158  -7.603  1.00 78.90  ? 499 PRO A N   1 
ATOM   7854 C CA  . PRO E 5 167 ? -2.594  -3.357  -7.646  1.00 75.99  ? 499 PRO A CA  1 
ATOM   7855 C C   . PRO E 5 167 ? -1.334  -4.184  -7.838  1.00 79.12  ? 499 PRO A C   1 
ATOM   7856 O O   . PRO E 5 167 ? -0.317  -3.641  -8.286  1.00 71.81  ? 499 PRO A O   1 
ATOM   7857 C CB  . PRO E 5 167 ? -2.594  -2.636  -6.290  1.00 61.31  ? 499 PRO A CB  1 
ATOM   7858 C CG  . PRO E 5 167 ? -3.468  -3.474  -5.411  1.00 75.84  ? 499 PRO A CG  1 
ATOM   7859 C CD  . PRO E 5 167 ? -4.526  -4.040  -6.310  1.00 77.53  ? 499 PRO A CD  1 
ATOM   7860 N N   . THR E 5 168 ? -1.370  -5.480  -7.519  1.00 78.43  ? 500 THR A N   1 
ATOM   7861 C CA  . THR E 5 168 ? -0.186  -6.323  -7.654  1.00 77.83  ? 500 THR A CA  1 
ATOM   7862 C C   . THR E 5 168 ? 0.112   -6.658  -9.114  1.00 88.80  ? 500 THR A C   1 
ATOM   7863 O O   . THR E 5 168 ? 1.278   -6.855  -9.477  1.00 87.43  ? 500 THR A O   1 
ATOM   7864 C CB  . THR E 5 168 ? -0.373  -7.596  -6.817  1.00 81.09  ? 500 THR A CB  1 
ATOM   7865 O OG1 . THR E 5 168 ? -0.081  -7.312  -5.443  1.00 89.79  ? 500 THR A OG1 1 
ATOM   7866 C CG2 . THR E 5 168 ? 0.520   -8.738  -7.297  1.00 81.84  ? 500 THR A CG2 1 
ATOM   7867 N N   . ASN E 5 169 ? -0.914  -6.677  -9.965  1.00 86.55  ? 501 ASN A N   1 
ATOM   7868 C CA  . ASN E 5 169 ? -0.787  -7.167  -11.332 1.00 76.19  ? 501 ASN A CA  1 
ATOM   7869 C C   . ASN E 5 169 ? 0.290   -6.412  -12.110 1.00 70.16  ? 501 ASN A C   1 
ATOM   7870 O O   . ASN E 5 169 ? 0.698   -5.302  -11.755 1.00 57.42  ? 501 ASN A O   1 
ATOM   7871 C CB  . ASN E 5 169 ? -2.121  -7.044  -12.067 1.00 70.47  ? 501 ASN A CB  1 
ATOM   7872 C CG  . ASN E 5 169 ? -3.256  -7.722  -11.332 1.00 78.50  ? 501 ASN A CG  1 
ATOM   7873 O OD1 . ASN E 5 169 ? -3.038  -8.625  -10.524 1.00 90.56  ? 501 ASN A OD1 1 
ATOM   7874 N ND2 . ASN E 5 169 ? -4.480  -7.294  -11.614 1.00 70.54  ? 501 ASN A ND2 1 
ATOM   7875 N N   . GLY E 5 170 ? 0.741   -7.034  -13.197 1.00 76.78  ? 502 GLY A N   1 
ATOM   7876 C CA  . GLY E 5 170 ? 1.708   -6.411  -14.075 1.00 57.36  ? 502 GLY A CA  1 
ATOM   7877 C C   . GLY E 5 170 ? 1.117   -5.237  -14.832 1.00 47.13  ? 502 GLY A C   1 
ATOM   7878 O O   . GLY E 5 170 ? -0.088  -4.981  -14.813 1.00 51.58  ? 502 GLY A O   1 
ATOM   7879 N N   . VAL E 5 171 ? 2.000   -4.513  -15.525 1.00 50.52  ? 503 VAL A N   1 
ATOM   7880 C CA  . VAL E 5 171 ? 1.613   -3.248  -16.146 1.00 52.66  ? 503 VAL A CA  1 
ATOM   7881 C C   . VAL E 5 171 ? 0.532   -3.466  -17.199 1.00 50.98  ? 503 VAL A C   1 
ATOM   7882 O O   . VAL E 5 171 ? -0.441  -2.705  -17.275 1.00 52.08  ? 503 VAL A O   1 
ATOM   7883 C CB  . VAL E 5 171 ? 2.847   -2.543  -16.737 1.00 42.56  ? 503 VAL A CB  1 
ATOM   7884 C CG1 . VAL E 5 171 ? 2.485   -1.139  -17.202 1.00 33.40  ? 503 VAL A CG1 1 
ATOM   7885 C CG2 . VAL E 5 171 ? 3.973   -2.500  -15.714 1.00 48.63  ? 503 VAL A CG2 1 
ATOM   7886 N N   . GLY E 5 172 ? 0.681   -4.504  -18.026 1.00 51.23  ? 504 GLY A N   1 
ATOM   7887 C CA  . GLY E 5 172 ? -0.312  -4.782  -19.050 1.00 47.51  ? 504 GLY A CA  1 
ATOM   7888 C C   . GLY E 5 172 ? -1.668  -5.161  -18.498 1.00 46.64  ? 504 GLY A C   1 
ATOM   7889 O O   . GLY E 5 172 ? -2.682  -4.979  -19.181 1.00 46.77  ? 504 GLY A O   1 
ATOM   7890 N N   . TYR E 5 173 ? -1.710  -5.685  -17.276 1.00 51.43  ? 505 TYR A N   1 
ATOM   7891 C CA  . TYR E 5 173 ? -2.957  -6.053  -16.620 1.00 48.58  ? 505 TYR A CA  1 
ATOM   7892 C C   . TYR E 5 173 ? -3.607  -4.886  -15.891 1.00 45.28  ? 505 TYR A C   1 
ATOM   7893 O O   . TYR E 5 173 ? -4.756  -5.012  -15.456 1.00 37.97  ? 505 TYR A O   1 
ATOM   7894 C CB  . TYR E 5 173 ? -2.719  -7.192  -15.616 1.00 51.64  ? 505 TYR A CB  1 
ATOM   7895 C CG  . TYR E 5 173 ? -2.268  -8.509  -16.223 1.00 52.94  ? 505 TYR A CG  1 
ATOM   7896 C CD1 . TYR E 5 173 ? -3.084  -9.635  -16.167 1.00 73.37  ? 505 TYR A CD1 1 
ATOM   7897 C CD2 . TYR E 5 173 ? -1.034  -8.629  -16.847 1.00 64.63  ? 505 TYR A CD2 1 
ATOM   7898 C CE1 . TYR E 5 173 ? -2.674  -10.839 -16.719 1.00 84.68  ? 505 TYR A CE1 1 
ATOM   7899 C CE2 . TYR E 5 173 ? -0.620  -9.819  -17.399 1.00 73.63  ? 505 TYR A CE2 1 
ATOM   7900 C CZ  . TYR E 5 173 ? -1.437  -10.918 -17.334 1.00 70.71  ? 505 TYR A CZ  1 
ATOM   7901 O OH  . TYR E 5 173 ? -0.981  -12.085 -17.897 1.00 63.89  ? 505 TYR A OH  1 
ATOM   7902 N N   . GLN E 5 174 ? -2.903  -3.766  -15.741 1.00 45.39  ? 506 GLN A N   1 
ATOM   7903 C CA  . GLN E 5 174 ? -3.419  -2.653  -14.963 1.00 44.82  ? 506 GLN A CA  1 
ATOM   7904 C C   . GLN E 5 174 ? -4.506  -1.907  -15.736 1.00 45.92  ? 506 GLN A C   1 
ATOM   7905 O O   . GLN E 5 174 ? -4.482  -1.857  -16.969 1.00 42.49  ? 506 GLN A O   1 
ATOM   7906 C CB  . GLN E 5 174 ? -2.289  -1.696  -14.596 1.00 36.25  ? 506 GLN A CB  1 
ATOM   7907 C CG  . GLN E 5 174 ? -1.251  -2.310  -13.674 1.00 42.03  ? 506 GLN A CG  1 
ATOM   7908 C CD  . GLN E 5 174 ? -0.148  -1.341  -13.306 1.00 46.97  ? 506 GLN A CD  1 
ATOM   7909 O OE1 . GLN E 5 174 ? -0.212  -0.156  -13.632 1.00 48.30  ? 506 GLN A OE1 1 
ATOM   7910 N NE2 . GLN E 5 174 ? 0.871   -1.839  -12.615 1.00 47.34  ? 506 GLN A NE2 1 
ATOM   7911 N N   . PRO E 5 175 ? -5.477  -1.324  -15.031 1.00 51.82  ? 507 PRO A N   1 
ATOM   7912 C CA  . PRO E 5 175 ? -6.516  -0.548  -15.715 1.00 44.55  ? 507 PRO A CA  1 
ATOM   7913 C C   . PRO E 5 175 ? -5.939  0.688   -16.389 1.00 44.41  ? 507 PRO A C   1 
ATOM   7914 O O   . PRO E 5 175 ? -4.995  1.311   -15.897 1.00 48.39  ? 507 PRO A O   1 
ATOM   7915 C CB  . PRO E 5 175 ? -7.479  -0.170  -14.583 1.00 43.41  ? 507 PRO A CB  1 
ATOM   7916 C CG  . PRO E 5 175 ? -6.636  -0.210  -13.350 1.00 57.56  ? 507 PRO A CG  1 
ATOM   7917 C CD  . PRO E 5 175 ? -5.661  -1.329  -13.570 1.00 51.85  ? 507 PRO A CD  1 
ATOM   7918 N N   . TYR E 5 176 ? -6.524  1.038   -17.532 1.00 35.27  ? 508 TYR A N   1 
ATOM   7919 C CA  . TYR E 5 176 ? -6.125  2.218   -18.290 1.00 26.98  ? 508 TYR A CA  1 
ATOM   7920 C C   . TYR E 5 176 ? -7.378  2.955   -18.731 1.00 33.54  ? 508 TYR A C   1 
ATOM   7921 O O   . TYR E 5 176 ? -8.224  2.382   -19.424 1.00 37.56  ? 508 TYR A O   1 
ATOM   7922 C CB  . TYR E 5 176 ? -5.269  1.836   -19.503 1.00 33.30  ? 508 TYR A CB  1 
ATOM   7923 C CG  . TYR E 5 176 ? -3.786  1.748   -19.216 1.00 36.52  ? 508 TYR A CG  1 
ATOM   7924 C CD1 . TYR E 5 176 ? -3.261  0.693   -18.482 1.00 39.62  ? 508 TYR A CD1 1 
ATOM   7925 C CD2 . TYR E 5 176 ? -2.910  2.715   -19.690 1.00 34.90  ? 508 TYR A CD2 1 
ATOM   7926 C CE1 . TYR E 5 176 ? -1.905  0.611   -18.219 1.00 42.89  ? 508 TYR A CE1 1 
ATOM   7927 C CE2 . TYR E 5 176 ? -1.553  2.641   -19.435 1.00 36.85  ? 508 TYR A CE2 1 
ATOM   7928 C CZ  . TYR E 5 176 ? -1.056  1.587   -18.698 1.00 36.46  ? 508 TYR A CZ  1 
ATOM   7929 O OH  . TYR E 5 176 ? 0.294   1.511   -18.441 1.00 35.32  ? 508 TYR A OH  1 
ATOM   7930 N N   . ARG E 5 177 ? -7.501  4.217   -18.327 1.00 34.31  ? 509 ARG A N   1 
ATOM   7931 C CA  . ARG E 5 177 ? -8.600  5.055   -18.787 1.00 35.73  ? 509 ARG A CA  1 
ATOM   7932 C C   . ARG E 5 177 ? -8.302  5.552   -20.195 1.00 32.62  ? 509 ARG A C   1 
ATOM   7933 O O   . ARG E 5 177 ? -7.221  6.089   -20.457 1.00 33.62  ? 509 ARG A O   1 
ATOM   7934 C CB  . ARG E 5 177 ? -8.814  6.234   -17.838 1.00 36.86  ? 509 ARG A CB  1 
ATOM   7935 C CG  . ARG E 5 177 ? -9.483  5.869   -16.519 1.00 41.26  ? 509 ARG A CG  1 
ATOM   7936 C CD  . ARG E 5 177 ? -9.104  6.857   -15.426 1.00 56.69  ? 509 ARG A CD  1 
ATOM   7937 N NE  . ARG E 5 177 ? -10.246 7.586   -14.889 1.00 56.48  ? 509 ARG A NE  1 
ATOM   7938 C CZ  . ARG E 5 177 ? -10.856 7.294   -13.748 1.00 56.22  ? 509 ARG A CZ  1 
ATOM   7939 N NH1 . ARG E 5 177 ? -10.470 6.274   -12.999 1.00 54.33  ? 509 ARG A NH1 1 
ATOM   7940 N NH2 . ARG E 5 177 ? -11.875 8.048   -13.345 1.00 53.60  ? 509 ARG A NH2 1 
ATOM   7941 N N   . VAL E 5 178 ? -9.259  5.371   -21.100 1.00 35.10  ? 510 VAL A N   1 
ATOM   7942 C CA  . VAL E 5 178 ? -9.084  5.686   -22.512 1.00 35.44  ? 510 VAL A CA  1 
ATOM   7943 C C   . VAL E 5 178 ? -10.153 6.685   -22.929 1.00 34.42  ? 510 VAL A C   1 
ATOM   7944 O O   . VAL E 5 178 ? -11.342 6.477   -22.663 1.00 32.10  ? 510 VAL A O   1 
ATOM   7945 C CB  . VAL E 5 178 ? -9.150  4.421   -23.388 1.00 29.10  ? 510 VAL A CB  1 
ATOM   7946 C CG1 . VAL E 5 178 ? -9.066  4.787   -24.862 1.00 23.53  ? 510 VAL A CG1 1 
ATOM   7947 C CG2 . VAL E 5 178 ? -8.039  3.457   -23.008 1.00 22.71  ? 510 VAL A CG2 1 
ATOM   7948 N N   . VAL E 5 179 ? -9.728  7.768   -23.576 1.00 32.67  ? 511 VAL A N   1 
ATOM   7949 C CA  . VAL E 5 179 ? -10.633 8.750   -24.161 1.00 37.13  ? 511 VAL A CA  1 
ATOM   7950 C C   . VAL E 5 179 ? -10.350 8.821   -25.655 1.00 40.36  ? 511 VAL A C   1 
ATOM   7951 O O   . VAL E 5 179 ? -9.203  9.032   -26.065 1.00 38.91  ? 511 VAL A O   1 
ATOM   7952 C CB  . VAL E 5 179 ? -10.483 10.137  -23.508 1.00 35.15  ? 511 VAL A CB  1 
ATOM   7953 C CG1 . VAL E 5 179 ? -11.495 11.106  -24.102 1.00 31.81  ? 511 VAL A CG1 1 
ATOM   7954 C CG2 . VAL E 5 179 ? -10.657 10.039  -22.001 1.00 27.12  ? 511 VAL A CG2 1 
ATOM   7955 N N   . VAL E 5 180 ? -11.393 8.647   -26.462 1.00 42.64  ? 512 VAL A N   1 
ATOM   7956 C CA  . VAL E 5 180 ? -11.285 8.671   -27.916 1.00 38.35  ? 512 VAL A CA  1 
ATOM   7957 C C   . VAL E 5 180 ? -12.037 9.893   -28.423 1.00 37.94  ? 512 VAL A C   1 
ATOM   7958 O O   . VAL E 5 180 ? -13.241 10.036  -28.179 1.00 38.32  ? 512 VAL A O   1 
ATOM   7959 C CB  . VAL E 5 180 ? -11.838 7.385   -28.549 1.00 31.09  ? 512 VAL A CB  1 
ATOM   7960 C CG1 . VAL E 5 180 ? -11.554 7.366   -30.044 1.00 29.91  ? 512 VAL A CG1 1 
ATOM   7961 C CG2 . VAL E 5 180 ? -11.246 6.160   -27.868 1.00 36.76  ? 512 VAL A CG2 1 
ATOM   7962 N N   . LEU E 5 181 ? -11.331 10.767  -29.134 1.00 27.44  ? 513 LEU A N   1 
ATOM   7963 C CA  . LEU E 5 181 ? -11.912 11.980  -29.693 1.00 35.94  ? 513 LEU A CA  1 
ATOM   7964 C C   . LEU E 5 181 ? -12.283 11.726  -31.149 1.00 35.01  ? 513 LEU A C   1 
ATOM   7965 O O   . LEU E 5 181 ? -11.426 11.349  -31.954 1.00 40.10  ? 513 LEU A O   1 
ATOM   7966 C CB  . LEU E 5 181 ? -10.939 13.153  -29.577 1.00 50.00  ? 513 LEU A CB  1 
ATOM   7967 C CG  . LEU E 5 181 ? -10.571 13.589  -28.157 1.00 48.59  ? 513 LEU A CG  1 
ATOM   7968 C CD1 . LEU E 5 181 ? -9.556  14.720  -28.190 1.00 44.04  ? 513 LEU A CD1 1 
ATOM   7969 C CD2 . LEU E 5 181 ? -11.815 14.003  -27.386 1.00 41.34  ? 513 LEU A CD2 1 
ATOM   7970 N N   . SER E 5 182 ? -13.556 11.929  -31.479 1.00 39.55  ? 514 SER A N   1 
ATOM   7971 C CA  . SER E 5 182 ? -14.076 11.717  -32.824 1.00 37.89  ? 514 SER A CA  1 
ATOM   7972 C C   . SER E 5 182 ? -14.612 13.035  -33.362 1.00 43.24  ? 514 SER A C   1 
ATOM   7973 O O   . SER E 5 182 ? -15.356 13.735  -32.667 1.00 51.58  ? 514 SER A O   1 
ATOM   7974 C CB  . SER E 5 182 ? -15.176 10.650  -32.825 1.00 27.22  ? 514 SER A CB  1 
ATOM   7975 O OG  . SER E 5 182 ? -15.756 10.508  -34.109 1.00 53.17  ? 514 SER A OG  1 
ATOM   7976 N N   . PHE E 5 183 ? -14.238 13.369  -34.594 1.00 39.10  ? 515 PHE A N   1 
ATOM   7977 C CA  . PHE E 5 183 ? -14.588 14.642  -35.206 1.00 54.98  ? 515 PHE A CA  1 
ATOM   7978 C C   . PHE E 5 183 ? -15.590 14.414  -36.329 1.00 62.83  ? 515 PHE A C   1 
ATOM   7979 O O   . PHE E 5 183 ? -15.357 13.589  -37.218 1.00 74.58  ? 515 PHE A O   1 
ATOM   7980 C CB  . PHE E 5 183 ? -13.341 15.353  -35.734 1.00 53.71  ? 515 PHE A CB  1 
ATOM   7981 C CG  . PHE E 5 183 ? -12.327 15.656  -34.670 1.00 50.42  ? 515 PHE A CG  1 
ATOM   7982 C CD1 . PHE E 5 183 ? -11.296 14.770  -34.404 1.00 51.17  ? 515 PHE A CD1 1 
ATOM   7983 C CD2 . PHE E 5 183 ? -12.413 16.820  -33.926 1.00 45.69  ? 515 PHE A CD2 1 
ATOM   7984 C CE1 . PHE E 5 183 ? -10.366 15.044  -33.419 1.00 67.17  ? 515 PHE A CE1 1 
ATOM   7985 C CE2 . PHE E 5 183 ? -11.486 17.100  -32.941 1.00 59.07  ? 515 PHE A CE2 1 
ATOM   7986 C CZ  . PHE E 5 183 ? -10.462 16.209  -32.686 1.00 68.48  ? 515 PHE A CZ  1 
ATOM   7987 N N   . GLU E 5 184 ? -16.701 15.145  -36.280 1.00 58.53  ? 516 GLU A N   1 
ATOM   7988 C CA  . GLU E 5 184 ? -17.772 15.039  -37.260 1.00 61.15  ? 516 GLU A CA  1 
ATOM   7989 C C   . GLU E 5 184 ? -17.959 16.379  -37.956 1.00 74.09  ? 516 GLU A C   1 
ATOM   7990 O O   . GLU E 5 184 ? -17.997 17.426  -37.301 1.00 73.40  ? 516 GLU A O   1 
ATOM   7991 C CB  . GLU E 5 184 ? -19.078 14.593  -36.597 1.00 58.31  ? 516 GLU A CB  1 
ATOM   7992 C CG  . GLU E 5 184 ? -20.331 15.019  -37.340 1.00 74.91  ? 516 GLU A CG  1 
ATOM   7993 C CD  . GLU E 5 184 ? -21.531 14.159  -37.000 1.00 75.65  ? 516 GLU A CD  1 
ATOM   7994 O OE1 . GLU E 5 184 ? -21.455 12.929  -37.207 1.00 83.19  ? 516 GLU A OE1 1 
ATOM   7995 O OE2 . GLU E 5 184 ? -22.545 14.709  -36.521 1.00 61.04  ? 516 GLU A OE2 1 
ATOM   7996 N N   . LEU E 5 185 ? -18.076 16.343  -39.287 1.00 71.89  ? 517 LEU A N   1 
ATOM   7997 C CA  . LEU E 5 185 ? -18.262 17.548  -40.099 1.00 71.85  ? 517 LEU A CA  1 
ATOM   7998 C C   . LEU E 5 185 ? -19.341 17.238  -41.137 1.00 77.84  ? 517 LEU A C   1 
ATOM   7999 O O   . LEU E 5 185 ? -19.057 16.684  -42.202 1.00 69.99  ? 517 LEU A O   1 
ATOM   8000 C CB  . LEU E 5 185 ? -16.950 17.988  -40.743 1.00 66.15  ? 517 LEU A CB  1 
ATOM   8001 C CG  . LEU E 5 185 ? -16.852 19.340  -41.461 1.00 70.32  ? 517 LEU A CG  1 
ATOM   8002 C CD1 . LEU E 5 185 ? -17.239 19.228  -42.930 1.00 74.58  ? 517 LEU A CD1 1 
ATOM   8003 C CD2 . LEU E 5 185 ? -17.701 20.391  -40.761 1.00 57.15  ? 517 LEU A CD2 1 
ATOM   8004 N N   . LEU E 5 186 ? -20.582 17.589  -40.807 1.00 88.53  ? 518 LEU A N   1 
ATOM   8005 C CA  . LEU E 5 186 ? -21.712 17.452  -41.712 1.00 86.20  ? 518 LEU A CA  1 
ATOM   8006 C C   . LEU E 5 186 ? -21.908 18.758  -42.481 1.00 91.62  ? 518 LEU A C   1 
ATOM   8007 O O   . LEU E 5 186 ? -21.057 19.651  -42.461 1.00 103.98 ? 518 LEU A O   1 
ATOM   8008 C CB  . LEU E 5 186 ? -22.969 17.063  -40.936 1.00 84.60  ? 518 LEU A CB  1 
ATOM   8009 C CG  . LEU E 5 186 ? -22.895 15.819  -40.048 1.00 84.24  ? 518 LEU A CG  1 
ATOM   8010 C CD1 . LEU E 5 186 ? -24.224 15.585  -39.345 1.00 68.49  ? 518 LEU A CD1 1 
ATOM   8011 C CD2 . LEU E 5 186 ? -22.494 14.601  -40.864 1.00 70.19  ? 518 LEU A CD2 1 
ATOM   8012 N N   . HIS E 5 187 ? -23.040 18.881  -43.173 1.00 93.76  ? 519 HIS A N   1 
ATOM   8013 C CA  . HIS E 5 187 ? -23.408 20.131  -43.827 1.00 98.62  ? 519 HIS A CA  1 
ATOM   8014 C C   . HIS E 5 187 ? -24.106 21.104  -42.886 1.00 98.38  ? 519 HIS A C   1 
ATOM   8015 O O   . HIS E 5 187 ? -24.433 22.220  -43.304 1.00 92.89  ? 519 HIS A O   1 
ATOM   8016 C CB  . HIS E 5 187 ? -24.297 19.851  -45.042 1.00 94.03  ? 519 HIS A CB  1 
ATOM   8017 C CG  . HIS E 5 187 ? -23.530 19.577  -46.298 1.00 102.84 ? 519 HIS A CG  1 
ATOM   8018 N ND1 . HIS E 5 187 ? -23.800 18.501  -47.117 1.00 96.11  ? 519 HIS A ND1 1 
ATOM   8019 C CD2 . HIS E 5 187 ? -22.504 20.243  -46.879 1.00 96.20  ? 519 HIS A CD2 1 
ATOM   8020 C CE1 . HIS E 5 187 ? -22.970 18.514  -48.145 1.00 95.95  ? 519 HIS A CE1 1 
ATOM   8021 N NE2 . HIS E 5 187 ? -22.175 19.562  -48.025 1.00 93.50  ? 519 HIS A NE2 1 
ATOM   8022 N N   . ALA E 5 188 ? -24.342 20.709  -41.637 1.00 102.15 ? 520 ALA A N   1 
ATOM   8023 C CA  . ALA E 5 188 ? -24.894 21.612  -40.647 1.00 90.69  ? 520 ALA A CA  1 
ATOM   8024 C C   . ALA E 5 188 ? -23.867 22.686  -40.290 1.00 101.08 ? 520 ALA A C   1 
ATOM   8025 O O   . ALA E 5 188 ? -22.664 22.491  -40.479 1.00 106.42 ? 520 ALA A O   1 
ATOM   8026 C CB  . ALA E 5 188 ? -25.310 20.836  -39.399 1.00 85.48  ? 520 ALA A CB  1 
ATOM   8027 N N   . PRO E 5 189 ? -24.320 23.839  -39.794 1.00 92.67  ? 521 PRO A N   1 
ATOM   8028 C CA  . PRO E 5 189 ? -23.372 24.899  -39.428 1.00 85.00  ? 521 PRO A CA  1 
ATOM   8029 C C   . PRO E 5 189 ? -22.384 24.425  -38.372 1.00 94.80  ? 521 PRO A C   1 
ATOM   8030 O O   . PRO E 5 189 ? -22.736 23.690  -37.447 1.00 93.84  ? 521 PRO A O   1 
ATOM   8031 C CB  . PRO E 5 189 ? -24.277 26.013  -38.890 1.00 76.74  ? 521 PRO A CB  1 
ATOM   8032 C CG  . PRO E 5 189 ? -25.597 25.769  -39.535 1.00 78.11  ? 521 PRO A CG  1 
ATOM   8033 C CD  . PRO E 5 189 ? -25.719 24.279  -39.651 1.00 79.36  ? 521 PRO A CD  1 
ATOM   8034 N N   . ALA E 5 190 ? -21.134 24.851  -38.526 1.00 85.91  ? 522 ALA A N   1 
ATOM   8035 C CA  . ALA E 5 190 ? -20.093 24.477  -37.581 1.00 72.17  ? 522 ALA A CA  1 
ATOM   8036 C C   . ALA E 5 190 ? -20.319 25.164  -36.240 1.00 69.16  ? 522 ALA A C   1 
ATOM   8037 O O   . ALA E 5 190 ? -20.629 26.356  -36.178 1.00 93.39  ? 522 ALA A O   1 
ATOM   8038 C CB  . ALA E 5 190 ? -18.719 24.841  -38.137 1.00 83.62  ? 522 ALA A CB  1 
ATOM   8039 N N   . THR E 5 191 ? -20.167 24.398  -35.157 1.00 66.12  ? 523 THR A N   1 
ATOM   8040 C CA  . THR E 5 191 ? -20.376 24.913  -33.812 1.00 61.33  ? 523 THR A CA  1 
ATOM   8041 C C   . THR E 5 191 ? -19.181 24.738  -32.886 1.00 74.40  ? 523 THR A C   1 
ATOM   8042 O O   . THR E 5 191 ? -19.140 25.390  -31.837 1.00 70.76  ? 523 THR A O   1 
ATOM   8043 C CB  . THR E 5 191 ? -21.595 24.242  -33.155 1.00 66.93  ? 523 THR A CB  1 
ATOM   8044 O OG1 . THR E 5 191 ? -21.185 23.034  -32.504 1.00 78.04  ? 523 THR A OG1 1 
ATOM   8045 C CG2 . THR E 5 191 ? -22.662 23.911  -34.189 1.00 68.48  ? 523 THR A CG2 1 
ATOM   8046 N N   . VAL E 5 192 ? -18.214 23.895  -33.236 1.00 76.89  ? 524 VAL A N   1 
ATOM   8047 C CA  . VAL E 5 192 ? -17.065 23.607  -32.384 1.00 74.50  ? 524 VAL A CA  1 
ATOM   8048 C C   . VAL E 5 192 ? -15.849 24.264  -33.025 1.00 72.52  ? 524 VAL A C   1 
ATOM   8049 O O   . VAL E 5 192 ? -15.236 23.701  -33.937 1.00 81.01  ? 524 VAL A O   1 
ATOM   8050 C CB  . VAL E 5 192 ? -16.851 22.101  -32.199 1.00 71.69  ? 524 VAL A CB  1 
ATOM   8051 C CG1 . VAL E 5 192 ? -15.754 21.843  -31.174 1.00 87.51  ? 524 VAL A CG1 1 
ATOM   8052 C CG2 . VAL E 5 192 ? -18.145 21.426  -31.788 1.00 52.76  ? 524 VAL A CG2 1 
ATOM   8053 N N   . CYS E 5 193 ? -15.485 25.448  -32.540 1.00 59.97  ? 525 CYS A N   1 
ATOM   8054 C CA  . CYS E 5 193 ? -14.330 26.178  -33.037 1.00 61.04  ? 525 CYS A CA  1 
ATOM   8055 C C   . CYS E 5 193 ? -13.328 26.398  -31.913 1.00 76.05  ? 525 CYS A C   1 
ATOM   8056 O O   . CYS E 5 193 ? -13.702 26.557  -30.748 1.00 80.08  ? 525 CYS A O   1 
ATOM   8057 C CB  . CYS E 5 193 ? -14.733 27.534  -33.626 1.00 90.43  ? 525 CYS A CB  1 
ATOM   8058 S SG  . CYS E 5 193 ? -15.923 27.483  -34.985 1.00 92.85  ? 525 CYS A SG  1 
ATOM   8059 N N   . GLY E 5 194 ? -12.048 26.399  -32.274 1.00 89.26  ? 526 GLY A N   1 
ATOM   8060 C CA  . GLY E 5 194 ? -10.994 26.718  -31.341 1.00 84.64  ? 526 GLY A CA  1 
ATOM   8061 C C   . GLY E 5 194 ? -10.625 28.186  -31.401 1.00 90.11  ? 526 GLY A C   1 
ATOM   8062 O O   . GLY E 5 194 ? -11.084 28.928  -32.275 1.00 90.52  ? 526 GLY A O   1 
ATOM   8063 N N   . PRO E 5 195 ? -9.784  28.640  -30.460 1.00 89.26  ? 527 PRO A N   1 
ATOM   8064 C CA  . PRO E 5 195 ? -9.315  30.030  -30.430 1.00 93.82  ? 527 PRO A CA  1 
ATOM   8065 C C   . PRO E 5 195 ? -8.525  30.412  -31.679 1.00 96.61  ? 527 PRO A C   1 
ATOM   8066 O O   . PRO E 5 195 ? -9.096  31.024  -32.582 1.00 97.22  ? 527 PRO A O   1 
ATOM   8067 C CB  . PRO E 5 195 ? -8.418  30.072  -29.188 1.00 91.29  ? 527 PRO A CB  1 
ATOM   8068 C CG  . PRO E 5 195 ? -8.898  28.947  -28.335 1.00 84.02  ? 527 PRO A CG  1 
ATOM   8069 C CD  . PRO E 5 195 ? -9.309  27.874  -29.296 1.00 85.21  ? 527 PRO A CD  1 
HETATM 8070 C C1  . NAG F 6 .   ? -8.030  16.953  -15.856 1.00 70.38  ? 1   NAG B C1  1 
HETATM 8071 C C2  . NAG F 6 .   ? -8.206  18.247  -16.666 1.00 60.06  ? 1   NAG B C2  1 
HETATM 8072 C C3  . NAG F 6 .   ? -6.906  19.046  -16.773 1.00 65.19  ? 1   NAG B C3  1 
HETATM 8073 C C4  . NAG F 6 .   ? -6.016  19.018  -15.531 1.00 54.17  ? 1   NAG B C4  1 
HETATM 8074 C C5  . NAG F 6 .   ? -6.049  17.683  -14.783 1.00 70.04  ? 1   NAG B C5  1 
HETATM 8075 C C6  . NAG F 6 .   ? -5.435  17.773  -13.402 1.00 59.45  ? 1   NAG B C6  1 
HETATM 8076 C C7  . NAG F 6 .   ? -9.153  18.825  -18.892 1.00 66.14  ? 1   NAG B C7  1 
HETATM 8077 C C8  . NAG F 6 .   ? -9.548  18.229  -20.220 1.00 64.08  ? 1   NAG B C8  1 
HETATM 8078 N N2  . NAG F 6 .   ? -8.662  17.940  -17.998 1.00 63.91  ? 1   NAG B N2  1 
HETATM 8079 O O3  . NAG F 6 .   ? -7.260  20.366  -17.100 1.00 62.46  ? 1   NAG B O3  1 
HETATM 8080 O O4  . NAG F 6 .   ? -4.716  19.262  -16.012 1.00 87.44  ? 1   NAG B O4  1 
HETATM 8081 O O5  . NAG F 6 .   ? -7.377  17.237  -14.641 1.00 81.22  ? 1   NAG B O5  1 
HETATM 8082 O O6  . NAG F 6 .   ? -4.484  16.749  -13.226 1.00 60.26  ? 1   NAG B O6  1 
HETATM 8083 O O7  . NAG F 6 .   ? -9.283  20.021  -18.673 1.00 63.10  ? 1   NAG B O7  1 
HETATM 8084 C C1  . NAG F 6 .   ? -4.322  20.592  -15.633 1.00 81.56  ? 2   NAG B C1  1 
HETATM 8085 C C2  . NAG F 6 .   ? -2.795  20.658  -15.645 1.00 88.96  ? 2   NAG B C2  1 
HETATM 8086 C C3  . NAG F 6 .   ? -2.402  22.021  -15.093 1.00 82.78  ? 2   NAG B C3  1 
HETATM 8087 C C4  . NAG F 6 .   ? -3.010  23.113  -15.972 1.00 90.61  ? 2   NAG B C4  1 
HETATM 8088 C C5  . NAG F 6 .   ? -4.522  22.891  -16.134 1.00 93.57  ? 2   NAG B C5  1 
HETATM 8089 C C6  . NAG F 6 .   ? -5.170  23.831  -17.129 1.00 91.11  ? 2   NAG B C6  1 
HETATM 8090 C C7  . NAG F 6 .   ? -1.676  18.471  -15.474 1.00 99.47  ? 2   NAG B C7  1 
HETATM 8091 C C8  . NAG F 6 .   ? -1.126  17.448  -14.509 1.00 78.07  ? 2   NAG B C8  1 
HETATM 8092 N N2  . NAG F 6 .   ? -2.215  19.568  -14.904 1.00 96.17  ? 2   NAG B N2  1 
HETATM 8093 O O3  . NAG F 6 .   ? -1.001  22.085  -15.041 1.00 89.78  ? 2   NAG B O3  1 
HETATM 8094 O O4  . NAG F 6 .   ? -2.745  24.351  -15.353 1.00 93.43  ? 2   NAG B O4  1 
HETATM 8095 O O5  . NAG F 6 .   ? -4.794  21.562  -16.539 1.00 89.90  ? 2   NAG B O5  1 
HETATM 8096 O O6  . NAG F 6 .   ? -5.400  25.081  -16.523 1.00 83.99  ? 2   NAG B O6  1 
HETATM 8097 O O7  . NAG F 6 .   ? -1.625  18.295  -16.683 1.00 93.27  ? 2   NAG B O7  1 
HETATM 8098 C C1  . BMA F 6 .   ? -1.754  25.085  -16.107 1.00 99.40  ? 3   BMA B C1  1 
HETATM 8099 C C2  . BMA F 6 .   ? -0.899  25.829  -15.086 1.00 113.36 ? 3   BMA B C2  1 
HETATM 8100 C C3  . BMA F 6 .   ? 0.278   26.526  -15.803 1.00 101.02 ? 3   BMA B C3  1 
HETATM 8101 C C4  . BMA F 6 .   ? 1.071   25.579  -16.722 1.00 99.93  ? 3   BMA B C4  1 
HETATM 8102 C C5  . BMA F 6 .   ? 0.164   24.714  -17.594 1.00 99.86  ? 3   BMA B C5  1 
HETATM 8103 C C6  . BMA F 6 .   ? 0.893   23.563  -18.284 1.00 82.05  ? 3   BMA B C6  1 
HETATM 8104 O O2  . BMA F 6 .   ? -0.484  24.910  -14.112 1.00 107.51 ? 3   BMA B O2  1 
HETATM 8105 O O3  . BMA F 6 .   ? 1.065   27.117  -14.800 1.00 89.61  ? 3   BMA B O3  1 
HETATM 8106 O O4  . BMA F 6 .   ? 1.891   26.412  -17.517 1.00 89.55  ? 3   BMA B O4  1 
HETATM 8107 O O5  . BMA F 6 .   ? -0.956  24.210  -16.887 1.00 111.53 ? 3   BMA B O5  1 
HETATM 8108 O O6  . BMA F 6 .   ? 1.840   23.041  -17.379 1.00 73.62  ? 3   BMA B O6  1 
# 
