data_9CPU
# 
_entry.id   9CPU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CPU         pdb_00009cpu 10.2210/pdb9cpu/pdb 
WWPDB D_1000286002 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CPU 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wilson@scripps.edu 
_pdbx_contact_author.name_first         Ian 
_pdbx_contact_author.name_last          Wilson 
_pdbx_contact_author.name_mi            A. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6469-2419 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Feng, Z.'     1 ? 
'Wilson, I.A.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structures of CR3022-like antibodies' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Feng, Z.'     1 ? 
primary 'Wilson, I.A.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man 'Spike protein S1' 23104.867 1   ? ? 'Receptor binding domain (UNP residues 333-530)' ? 
2 polymer  man 'C03-0304 Fab heavy chain' 23487.443 1   ? ? ?                                                ? 
3 polymer  man 'CC12.3 Fab heavy chain' 23377.150 1   ? ? ?                                                ? 
4 polymer  man 'C03-0304 Fab light chain' 24304.000 1   ? ? ?                                                ? 
5 polymer  man 'CC12.3 Fab light chain' 23344.883 1   ? ? ?                                                ? 
6 branched man 
'beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 586.542   1   
? ? ?                                                ? 
7 water    nat water 18.015    404 ? ? ?                                                ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSGHHHHHH
;
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSGHHHHHH
;
A ? 
2 'polypeptide(L)' no no 
;EVQLVQSGAEVKKPGESLKISCKGSGYSFITYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSINTAY
LQWSSLKASDTAMYYCAGSSGISTPMDVWGRGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW
NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
;EVQLVQSGAEVKKPGESLKISCKGSGYSFITYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSINTAY
LQWSSLKASDTAMYYCAGSSGISTPMDVWGRGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW
NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
H ? 
3 'polypeptide(L)' no no 
;QVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTFYADSVKGRFTISRDNSKSTLYL
QMNSLRVEDTAVYYCARDFGDFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
;QVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIYSGGSTFYADSVKGRFTISRDNSKSTLYL
QMNSLRVEDTAVYYCARDFGDFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
;
F ? 
4 'polypeptide(L)' no no 
;DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSFNKDYLAWYQQKPGQPPKLLIYWASIRESGVPDRFSGSGSGTDFTLT
ISGLQAEDVAVYYCQQYSRTPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSFNKDYLAWYQQKPGQPPKLLIYWASIRESGVPDRFSGSGSGTDFTLT
ISGLQAEDVAVYYCQQYSRTPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
5 'polypeptide(L)' no no 
;EIVLTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEP
EDFAVYYCQQYGSSPRTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;EIVLTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEP
EDFAVYYCQQYGSSPRTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
G ? 
# 
_pdbx_entity_nonpoly.entity_id   7 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   THR n 
1 2   ASN n 
1 3   LEU n 
1 4   CYS n 
1 5   PRO n 
1 6   PHE n 
1 7   GLY n 
1 8   GLU n 
1 9   VAL n 
1 10  PHE n 
1 11  ASN n 
1 12  ALA n 
1 13  THR n 
1 14  ARG n 
1 15  PHE n 
1 16  ALA n 
1 17  SER n 
1 18  VAL n 
1 19  TYR n 
1 20  ALA n 
1 21  TRP n 
1 22  ASN n 
1 23  ARG n 
1 24  LYS n 
1 25  ARG n 
1 26  ILE n 
1 27  SER n 
1 28  ASN n 
1 29  CYS n 
1 30  VAL n 
1 31  ALA n 
1 32  ASP n 
1 33  TYR n 
1 34  SER n 
1 35  VAL n 
1 36  LEU n 
1 37  TYR n 
1 38  ASN n 
1 39  SER n 
1 40  ALA n 
1 41  SER n 
1 42  PHE n 
1 43  SER n 
1 44  THR n 
1 45  PHE n 
1 46  LYS n 
1 47  CYS n 
1 48  TYR n 
1 49  GLY n 
1 50  VAL n 
1 51  SER n 
1 52  PRO n 
1 53  THR n 
1 54  LYS n 
1 55  LEU n 
1 56  ASN n 
1 57  ASP n 
1 58  LEU n 
1 59  CYS n 
1 60  PHE n 
1 61  THR n 
1 62  ASN n 
1 63  VAL n 
1 64  TYR n 
1 65  ALA n 
1 66  ASP n 
1 67  SER n 
1 68  PHE n 
1 69  VAL n 
1 70  ILE n 
1 71  ARG n 
1 72  GLY n 
1 73  ASP n 
1 74  GLU n 
1 75  VAL n 
1 76  ARG n 
1 77  GLN n 
1 78  ILE n 
1 79  ALA n 
1 80  PRO n 
1 81  GLY n 
1 82  GLN n 
1 83  THR n 
1 84  GLY n 
1 85  LYS n 
1 86  ILE n 
1 87  ALA n 
1 88  ASP n 
1 89  TYR n 
1 90  ASN n 
1 91  TYR n 
1 92  LYS n 
1 93  LEU n 
1 94  PRO n 
1 95  ASP n 
1 96  ASP n 
1 97  PHE n 
1 98  THR n 
1 99  GLY n 
1 100 CYS n 
1 101 VAL n 
1 102 ILE n 
1 103 ALA n 
1 104 TRP n 
1 105 ASN n 
1 106 SER n 
1 107 ASN n 
1 108 ASN n 
1 109 LEU n 
1 110 ASP n 
1 111 SER n 
1 112 LYS n 
1 113 VAL n 
1 114 GLY n 
1 115 GLY n 
1 116 ASN n 
1 117 TYR n 
1 118 ASN n 
1 119 TYR n 
1 120 LEU n 
1 121 TYR n 
1 122 ARG n 
1 123 LEU n 
1 124 PHE n 
1 125 ARG n 
1 126 LYS n 
1 127 SER n 
1 128 ASN n 
1 129 LEU n 
1 130 LYS n 
1 131 PRO n 
1 132 PHE n 
1 133 GLU n 
1 134 ARG n 
1 135 ASP n 
1 136 ILE n 
1 137 SER n 
1 138 THR n 
1 139 GLU n 
1 140 ILE n 
1 141 TYR n 
1 142 GLN n 
1 143 ALA n 
1 144 GLY n 
1 145 SER n 
1 146 THR n 
1 147 PRO n 
1 148 CYS n 
1 149 ASN n 
1 150 GLY n 
1 151 VAL n 
1 152 GLU n 
1 153 GLY n 
1 154 PHE n 
1 155 ASN n 
1 156 CYS n 
1 157 TYR n 
1 158 PHE n 
1 159 PRO n 
1 160 LEU n 
1 161 GLN n 
1 162 SER n 
1 163 TYR n 
1 164 GLY n 
1 165 PHE n 
1 166 GLN n 
1 167 PRO n 
1 168 THR n 
1 169 ASN n 
1 170 GLY n 
1 171 VAL n 
1 172 GLY n 
1 173 TYR n 
1 174 GLN n 
1 175 PRO n 
1 176 TYR n 
1 177 ARG n 
1 178 VAL n 
1 179 VAL n 
1 180 VAL n 
1 181 LEU n 
1 182 SER n 
1 183 PHE n 
1 184 GLU n 
1 185 LEU n 
1 186 LEU n 
1 187 HIS n 
1 188 ALA n 
1 189 PRO n 
1 190 ALA n 
1 191 THR n 
1 192 VAL n 
1 193 CYS n 
1 194 GLY n 
1 195 PRO n 
1 196 LYS n 
1 197 LYS n 
1 198 SER n 
1 199 GLY n 
1 200 HIS n 
1 201 HIS n 
1 202 HIS n 
1 203 HIS n 
1 204 HIS n 
1 205 HIS n 
2 1   GLU n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   VAL n 
2 6   GLN n 
2 7   SER n 
2 8   GLY n 
2 9   ALA n 
2 10  GLU n 
2 11  VAL n 
2 12  LYS n 
2 13  LYS n 
2 14  PRO n 
2 15  GLY n 
2 16  GLU n 
2 17  SER n 
2 18  LEU n 
2 19  LYS n 
2 20  ILE n 
2 21  SER n 
2 22  CYS n 
2 23  LYS n 
2 24  GLY n 
2 25  SER n 
2 26  GLY n 
2 27  TYR n 
2 28  SER n 
2 29  PHE n 
2 30  ILE n 
2 31  THR n 
2 32  TYR n 
2 33  TRP n 
2 34  ILE n 
2 35  GLY n 
2 36  TRP n 
2 37  VAL n 
2 38  ARG n 
2 39  GLN n 
2 40  MET n 
2 41  PRO n 
2 42  GLY n 
2 43  LYS n 
2 44  GLY n 
2 45  LEU n 
2 46  GLU n 
2 47  TRP n 
2 48  MET n 
2 49  GLY n 
2 50  ILE n 
2 51  ILE n 
2 52  TYR n 
2 53  PRO n 
2 54  GLY n 
2 55  ASP n 
2 56  SER n 
2 57  ASP n 
2 58  THR n 
2 59  ARG n 
2 60  TYR n 
2 61  SER n 
2 62  PRO n 
2 63  SER n 
2 64  PHE n 
2 65  GLN n 
2 66  GLY n 
2 67  GLN n 
2 68  VAL n 
2 69  THR n 
2 70  ILE n 
2 71  SER n 
2 72  ALA n 
2 73  ASP n 
2 74  LYS n 
2 75  SER n 
2 76  ILE n 
2 77  ASN n 
2 78  THR n 
2 79  ALA n 
2 80  TYR n 
2 81  LEU n 
2 82  GLN n 
2 83  TRP n 
2 84  SER n 
2 85  SER n 
2 86  LEU n 
2 87  LYS n 
2 88  ALA n 
2 89  SER n 
2 90  ASP n 
2 91  THR n 
2 92  ALA n 
2 93  MET n 
2 94  TYR n 
2 95  TYR n 
2 96  CYS n 
2 97  ALA n 
2 98  GLY n 
2 99  SER n 
2 100 SER n 
2 101 GLY n 
2 102 ILE n 
2 103 SER n 
2 104 THR n 
2 105 PRO n 
2 106 MET n 
2 107 ASP n 
2 108 VAL n 
2 109 TRP n 
2 110 GLY n 
2 111 ARG n 
2 112 GLY n 
2 113 THR n 
2 114 THR n 
2 115 VAL n 
2 116 THR n 
2 117 VAL n 
2 118 SER n 
2 119 SER n 
2 120 ALA n 
2 121 SER n 
2 122 THR n 
2 123 LYS n 
2 124 GLY n 
2 125 PRO n 
2 126 SER n 
2 127 VAL n 
2 128 PHE n 
2 129 PRO n 
2 130 LEU n 
2 131 ALA n 
2 132 PRO n 
2 133 SER n 
2 134 SER n 
2 135 LYS n 
2 136 SER n 
2 137 THR n 
2 138 SER n 
2 139 GLY n 
2 140 GLY n 
2 141 THR n 
2 142 ALA n 
2 143 ALA n 
2 144 LEU n 
2 145 GLY n 
2 146 CYS n 
2 147 LEU n 
2 148 VAL n 
2 149 LYS n 
2 150 ASP n 
2 151 TYR n 
2 152 PHE n 
2 153 PRO n 
2 154 GLU n 
2 155 PRO n 
2 156 VAL n 
2 157 THR n 
2 158 VAL n 
2 159 SER n 
2 160 TRP n 
2 161 ASN n 
2 162 SER n 
2 163 GLY n 
2 164 ALA n 
2 165 LEU n 
2 166 THR n 
2 167 SER n 
2 168 GLY n 
2 169 VAL n 
2 170 HIS n 
2 171 THR n 
2 172 PHE n 
2 173 PRO n 
2 174 ALA n 
2 175 VAL n 
2 176 LEU n 
2 177 GLN n 
2 178 SER n 
2 179 SER n 
2 180 GLY n 
2 181 LEU n 
2 182 TYR n 
2 183 SER n 
2 184 LEU n 
2 185 SER n 
2 186 SER n 
2 187 VAL n 
2 188 VAL n 
2 189 THR n 
2 190 VAL n 
2 191 PRO n 
2 192 SER n 
2 193 SER n 
2 194 SER n 
2 195 LEU n 
2 196 GLY n 
2 197 THR n 
2 198 GLN n 
2 199 THR n 
2 200 TYR n 
2 201 ILE n 
2 202 CYS n 
2 203 ASN n 
2 204 VAL n 
2 205 ASN n 
2 206 HIS n 
2 207 LYS n 
2 208 PRO n 
2 209 SER n 
2 210 ASN n 
2 211 THR n 
2 212 LYS n 
2 213 VAL n 
2 214 ASP n 
2 215 LYS n 
2 216 LYS n 
2 217 VAL n 
2 218 GLU n 
2 219 PRO n 
2 220 LYS n 
2 221 SER n 
2 222 CYS n 
3 1   GLN n 
3 2   VAL n 
3 3   GLN n 
3 4   LEU n 
3 5   VAL n 
3 6   GLU n 
3 7   SER n 
3 8   GLY n 
3 9   GLY n 
3 10  GLY n 
3 11  LEU n 
3 12  ILE n 
3 13  GLN n 
3 14  PRO n 
3 15  GLY n 
3 16  GLY n 
3 17  SER n 
3 18  LEU n 
3 19  ARG n 
3 20  LEU n 
3 21  SER n 
3 22  CYS n 
3 23  ALA n 
3 24  ALA n 
3 25  SER n 
3 26  GLY n 
3 27  PHE n 
3 28  THR n 
3 29  VAL n 
3 30  SER n 
3 31  SER n 
3 32  ASN n 
3 33  TYR n 
3 34  MET n 
3 35  SER n 
3 36  TRP n 
3 37  VAL n 
3 38  ARG n 
3 39  GLN n 
3 40  ALA n 
3 41  PRO n 
3 42  GLY n 
3 43  LYS n 
3 44  GLY n 
3 45  LEU n 
3 46  GLU n 
3 47  TRP n 
3 48  VAL n 
3 49  SER n 
3 50  VAL n 
3 51  ILE n 
3 52  TYR n 
3 53  SER n 
3 54  GLY n 
3 55  GLY n 
3 56  SER n 
3 57  THR n 
3 58  PHE n 
3 59  TYR n 
3 60  ALA n 
3 61  ASP n 
3 62  SER n 
3 63  VAL n 
3 64  LYS n 
3 65  GLY n 
3 66  ARG n 
3 67  PHE n 
3 68  THR n 
3 69  ILE n 
3 70  SER n 
3 71  ARG n 
3 72  ASP n 
3 73  ASN n 
3 74  SER n 
3 75  LYS n 
3 76  SER n 
3 77  THR n 
3 78  LEU n 
3 79  TYR n 
3 80  LEU n 
3 81  GLN n 
3 82  MET n 
3 83  ASN n 
3 84  SER n 
3 85  LEU n 
3 86  ARG n 
3 87  VAL n 
3 88  GLU n 
3 89  ASP n 
3 90  THR n 
3 91  ALA n 
3 92  VAL n 
3 93  TYR n 
3 94  TYR n 
3 95  CYS n 
3 96  ALA n 
3 97  ARG n 
3 98  ASP n 
3 99  PHE n 
3 100 GLY n 
3 101 ASP n 
3 102 PHE n 
3 103 TYR n 
3 104 PHE n 
3 105 ASP n 
3 106 TYR n 
3 107 TRP n 
3 108 GLY n 
3 109 GLN n 
3 110 GLY n 
3 111 THR n 
3 112 LEU n 
3 113 VAL n 
3 114 THR n 
3 115 VAL n 
3 116 SER n 
3 117 SER n 
3 118 ALA n 
3 119 SER n 
3 120 THR n 
3 121 LYS n 
3 122 GLY n 
3 123 PRO n 
3 124 SER n 
3 125 VAL n 
3 126 PHE n 
3 127 PRO n 
3 128 LEU n 
3 129 ALA n 
3 130 PRO n 
3 131 SER n 
3 132 SER n 
3 133 LYS n 
3 134 SER n 
3 135 THR n 
3 136 SER n 
3 137 GLY n 
3 138 GLY n 
3 139 THR n 
3 140 ALA n 
3 141 ALA n 
3 142 LEU n 
3 143 GLY n 
3 144 CYS n 
3 145 LEU n 
3 146 VAL n 
3 147 LYS n 
3 148 ASP n 
3 149 TYR n 
3 150 PHE n 
3 151 PRO n 
3 152 GLU n 
3 153 PRO n 
3 154 VAL n 
3 155 THR n 
3 156 VAL n 
3 157 SER n 
3 158 TRP n 
3 159 ASN n 
3 160 SER n 
3 161 GLY n 
3 162 ALA n 
3 163 LEU n 
3 164 THR n 
3 165 SER n 
3 166 GLY n 
3 167 VAL n 
3 168 HIS n 
3 169 THR n 
3 170 PHE n 
3 171 PRO n 
3 172 ALA n 
3 173 VAL n 
3 174 LEU n 
3 175 GLN n 
3 176 SER n 
3 177 SER n 
3 178 GLY n 
3 179 LEU n 
3 180 TYR n 
3 181 SER n 
3 182 LEU n 
3 183 SER n 
3 184 SER n 
3 185 VAL n 
3 186 VAL n 
3 187 THR n 
3 188 VAL n 
3 189 PRO n 
3 190 SER n 
3 191 SER n 
3 192 SER n 
3 193 LEU n 
3 194 GLY n 
3 195 THR n 
3 196 GLN n 
3 197 THR n 
3 198 TYR n 
3 199 ILE n 
3 200 CYS n 
3 201 ASN n 
3 202 VAL n 
3 203 ASN n 
3 204 HIS n 
3 205 LYS n 
3 206 PRO n 
3 207 SER n 
3 208 ASN n 
3 209 THR n 
3 210 LYS n 
3 211 VAL n 
3 212 ASP n 
3 213 LYS n 
3 214 LYS n 
3 215 VAL n 
3 216 GLU n 
3 217 PRO n 
3 218 LYS n 
3 219 SER n 
3 220 CYS n 
4 1   ASP n 
4 2   ILE n 
4 3   VAL n 
4 4   MET n 
4 5   THR n 
4 6   GLN n 
4 7   SER n 
4 8   PRO n 
4 9   ASP n 
4 10  SER n 
4 11  LEU n 
4 12  ALA n 
4 13  VAL n 
4 14  SER n 
4 15  LEU n 
4 16  GLY n 
4 17  GLU n 
4 18  ARG n 
4 19  ALA n 
4 20  THR n 
4 21  ILE n 
4 22  ASN n 
4 23  CYS n 
4 24  LYS n 
4 25  SER n 
4 26  SER n 
4 27  GLN n 
4 28  SER n 
4 29  VAL n 
4 30  LEU n 
4 31  TYR n 
4 32  SER n 
4 33  SER n 
4 34  PHE n 
4 35  ASN n 
4 36  LYS n 
4 37  ASP n 
4 38  TYR n 
4 39  LEU n 
4 40  ALA n 
4 41  TRP n 
4 42  TYR n 
4 43  GLN n 
4 44  GLN n 
4 45  LYS n 
4 46  PRO n 
4 47  GLY n 
4 48  GLN n 
4 49  PRO n 
4 50  PRO n 
4 51  LYS n 
4 52  LEU n 
4 53  LEU n 
4 54  ILE n 
4 55  TYR n 
4 56  TRP n 
4 57  ALA n 
4 58  SER n 
4 59  ILE n 
4 60  ARG n 
4 61  GLU n 
4 62  SER n 
4 63  GLY n 
4 64  VAL n 
4 65  PRO n 
4 66  ASP n 
4 67  ARG n 
4 68  PHE n 
4 69  SER n 
4 70  GLY n 
4 71  SER n 
4 72  GLY n 
4 73  SER n 
4 74  GLY n 
4 75  THR n 
4 76  ASP n 
4 77  PHE n 
4 78  THR n 
4 79  LEU n 
4 80  THR n 
4 81  ILE n 
4 82  SER n 
4 83  GLY n 
4 84  LEU n 
4 85  GLN n 
4 86  ALA n 
4 87  GLU n 
4 88  ASP n 
4 89  VAL n 
4 90  ALA n 
4 91  VAL n 
4 92  TYR n 
4 93  TYR n 
4 94  CYS n 
4 95  GLN n 
4 96  GLN n 
4 97  TYR n 
4 98  SER n 
4 99  ARG n 
4 100 THR n 
4 101 PRO n 
4 102 TYR n 
4 103 THR n 
4 104 PHE n 
4 105 GLY n 
4 106 GLN n 
4 107 GLY n 
4 108 THR n 
4 109 LYS n 
4 110 LEU n 
4 111 GLU n 
4 112 ILE n 
4 113 LYS n 
4 114 ARG n 
4 115 THR n 
4 116 VAL n 
4 117 ALA n 
4 118 ALA n 
4 119 PRO n 
4 120 SER n 
4 121 VAL n 
4 122 PHE n 
4 123 ILE n 
4 124 PHE n 
4 125 PRO n 
4 126 PRO n 
4 127 SER n 
4 128 ASP n 
4 129 GLU n 
4 130 GLN n 
4 131 LEU n 
4 132 LYS n 
4 133 SER n 
4 134 GLY n 
4 135 THR n 
4 136 ALA n 
4 137 SER n 
4 138 VAL n 
4 139 VAL n 
4 140 CYS n 
4 141 LEU n 
4 142 LEU n 
4 143 ASN n 
4 144 ASN n 
4 145 PHE n 
4 146 TYR n 
4 147 PRO n 
4 148 ARG n 
4 149 GLU n 
4 150 ALA n 
4 151 LYS n 
4 152 VAL n 
4 153 GLN n 
4 154 TRP n 
4 155 LYS n 
4 156 VAL n 
4 157 ASP n 
4 158 ASN n 
4 159 ALA n 
4 160 LEU n 
4 161 GLN n 
4 162 SER n 
4 163 GLY n 
4 164 ASN n 
4 165 SER n 
4 166 GLN n 
4 167 GLU n 
4 168 SER n 
4 169 VAL n 
4 170 THR n 
4 171 GLU n 
4 172 GLN n 
4 173 ASP n 
4 174 SER n 
4 175 LYS n 
4 176 ASP n 
4 177 SER n 
4 178 THR n 
4 179 TYR n 
4 180 SER n 
4 181 LEU n 
4 182 SER n 
4 183 SER n 
4 184 THR n 
4 185 LEU n 
4 186 THR n 
4 187 LEU n 
4 188 SER n 
4 189 LYS n 
4 190 ALA n 
4 191 ASP n 
4 192 TYR n 
4 193 GLU n 
4 194 LYS n 
4 195 HIS n 
4 196 LYS n 
4 197 VAL n 
4 198 TYR n 
4 199 ALA n 
4 200 CYS n 
4 201 GLU n 
4 202 VAL n 
4 203 THR n 
4 204 HIS n 
4 205 GLN n 
4 206 GLY n 
4 207 LEU n 
4 208 SER n 
4 209 SER n 
4 210 PRO n 
4 211 VAL n 
4 212 THR n 
4 213 LYS n 
4 214 SER n 
4 215 PHE n 
4 216 ASN n 
4 217 ARG n 
4 218 GLY n 
4 219 GLU n 
4 220 CYS n 
5 1   GLU n 
5 2   ILE n 
5 3   VAL n 
5 4   LEU n 
5 5   THR n 
5 6   GLN n 
5 7   SER n 
5 8   PRO n 
5 9   GLY n 
5 10  THR n 
5 11  LEU n 
5 12  SER n 
5 13  LEU n 
5 14  SER n 
5 15  PRO n 
5 16  GLY n 
5 17  GLU n 
5 18  ARG n 
5 19  ALA n 
5 20  THR n 
5 21  LEU n 
5 22  SER n 
5 23  CYS n 
5 24  ARG n 
5 25  ALA n 
5 26  SER n 
5 27  GLN n 
5 28  SER n 
5 29  VAL n 
5 30  SER n 
5 31  SER n 
5 32  TYR n 
5 33  LEU n 
5 34  ALA n 
5 35  TRP n 
5 36  TYR n 
5 37  GLN n 
5 38  GLN n 
5 39  LYS n 
5 40  PRO n 
5 41  GLY n 
5 42  GLN n 
5 43  ALA n 
5 44  PRO n 
5 45  ARG n 
5 46  LEU n 
5 47  LEU n 
5 48  ILE n 
5 49  TYR n 
5 50  GLY n 
5 51  ALA n 
5 52  SER n 
5 53  SER n 
5 54  ARG n 
5 55  ALA n 
5 56  THR n 
5 57  GLY n 
5 58  ILE n 
5 59  PRO n 
5 60  ASP n 
5 61  ARG n 
5 62  PHE n 
5 63  SER n 
5 64  GLY n 
5 65  SER n 
5 66  GLY n 
5 67  SER n 
5 68  GLY n 
5 69  THR n 
5 70  ASP n 
5 71  PHE n 
5 72  THR n 
5 73  LEU n 
5 74  THR n 
5 75  ILE n 
5 76  SER n 
5 77  ARG n 
5 78  LEU n 
5 79  GLU n 
5 80  PRO n 
5 81  GLU n 
5 82  ASP n 
5 83  PHE n 
5 84  ALA n 
5 85  VAL n 
5 86  TYR n 
5 87  TYR n 
5 88  CYS n 
5 89  GLN n 
5 90  GLN n 
5 91  TYR n 
5 92  GLY n 
5 93  SER n 
5 94  SER n 
5 95  PRO n 
5 96  ARG n 
5 97  THR n 
5 98  PHE n 
5 99  GLY n 
5 100 GLN n 
5 101 GLY n 
5 102 THR n 
5 103 LYS n 
5 104 LEU n 
5 105 GLU n 
5 106 ILE n 
5 107 LYS n 
5 108 ARG n 
5 109 THR n 
5 110 VAL n 
5 111 ALA n 
5 112 ALA n 
5 113 PRO n 
5 114 SER n 
5 115 VAL n 
5 116 PHE n 
5 117 ILE n 
5 118 PHE n 
5 119 PRO n 
5 120 PRO n 
5 121 SER n 
5 122 ASP n 
5 123 GLU n 
5 124 GLN n 
5 125 LEU n 
5 126 LYS n 
5 127 SER n 
5 128 GLY n 
5 129 THR n 
5 130 ALA n 
5 131 SER n 
5 132 VAL n 
5 133 VAL n 
5 134 CYS n 
5 135 LEU n 
5 136 LEU n 
5 137 ASN n 
5 138 ASN n 
5 139 PHE n 
5 140 TYR n 
5 141 PRO n 
5 142 ARG n 
5 143 GLU n 
5 144 ALA n 
5 145 LYS n 
5 146 VAL n 
5 147 GLN n 
5 148 TRP n 
5 149 LYS n 
5 150 VAL n 
5 151 ASP n 
5 152 ASN n 
5 153 ALA n 
5 154 LEU n 
5 155 GLN n 
5 156 SER n 
5 157 GLY n 
5 158 ASN n 
5 159 SER n 
5 160 GLN n 
5 161 GLU n 
5 162 SER n 
5 163 VAL n 
5 164 THR n 
5 165 GLU n 
5 166 GLN n 
5 167 ASP n 
5 168 SER n 
5 169 LYS n 
5 170 ASP n 
5 171 SER n 
5 172 THR n 
5 173 TYR n 
5 174 SER n 
5 175 LEU n 
5 176 SER n 
5 177 SER n 
5 178 THR n 
5 179 LEU n 
5 180 THR n 
5 181 LEU n 
5 182 SER n 
5 183 LYS n 
5 184 ALA n 
5 185 ASP n 
5 186 TYR n 
5 187 GLU n 
5 188 LYS n 
5 189 HIS n 
5 190 LYS n 
5 191 VAL n 
5 192 TYR n 
5 193 ALA n 
5 194 CYS n 
5 195 GLU n 
5 196 VAL n 
5 197 THR n 
5 198 HIS n 
5 199 GLN n 
5 200 GLY n 
5 201 LEU n 
5 202 SER n 
5 203 SER n 
5 204 PRO n 
5 205 VAL n 
5 206 THR n 
5 207 LYS n 
5 208 SER n 
5 209 PHE n 
5 210 ASN n 
5 211 ARG n 
5 212 GLY n 
5 213 GLU n 
5 214 CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 205 ?     ? ? ? ? ? ? ? ? 'Severe acute respiratory syndrome coronavirus 2' 2697049 ? ? ? ? ? ? 
? 'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 222 mouse ? ? ? ? ? ? ? ? 'Mus musculus'                                    10090   ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 220 human ? ? ? ? ? ? ? ? 'Homo sapiens'                                    9606    ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 220 mouse ? ? ? ? ? ? ? ? 'Mus musculus'                                    10090   ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 214 human ? ? ? ? ? ? ? ? 'Homo sapiens'                                    9606    ? ? ? ? ? ? 
? human           'Homo sapiens'          9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   6 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 6 DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH                                          'Glycam Condensed Sequence' GMML       1.0   
2 6 'WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5]/1-1-2/a4-b1_b4-c1' WURCS                       PDB2Glycan 1.1.0 
3 6 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}}'           LINUCS                      PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 6 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 6 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking' . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                  . WATER                                    ? 'H2 O'           18.015  
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   THR 1   333 333 THR THR A . n 
A 1 2   ASN 2   334 334 ASN ASN A . n 
A 1 3   LEU 3   335 335 LEU LEU A . n 
A 1 4   CYS 4   336 336 CYS CYS A . n 
A 1 5   PRO 5   337 337 PRO PRO A . n 
A 1 6   PHE 6   338 338 PHE PHE A . n 
A 1 7   GLY 7   339 339 GLY GLY A . n 
A 1 8   GLU 8   340 340 GLU GLU A . n 
A 1 9   VAL 9   341 341 VAL VAL A . n 
A 1 10  PHE 10  342 342 PHE PHE A . n 
A 1 11  ASN 11  343 343 ASN ASN A . n 
A 1 12  ALA 12  344 344 ALA ALA A . n 
A 1 13  THR 13  345 345 THR THR A . n 
A 1 14  ARG 14  346 346 ARG ARG A . n 
A 1 15  PHE 15  347 347 PHE PHE A . n 
A 1 16  ALA 16  348 348 ALA ALA A . n 
A 1 17  SER 17  349 349 SER SER A . n 
A 1 18  VAL 18  350 350 VAL VAL A . n 
A 1 19  TYR 19  351 351 TYR TYR A . n 
A 1 20  ALA 20  352 352 ALA ALA A . n 
A 1 21  TRP 21  353 353 TRP TRP A . n 
A 1 22  ASN 22  354 354 ASN ASN A . n 
A 1 23  ARG 23  355 355 ARG ARG A . n 
A 1 24  LYS 24  356 356 LYS LYS A . n 
A 1 25  ARG 25  357 357 ARG ARG A . n 
A 1 26  ILE 26  358 358 ILE ILE A . n 
A 1 27  SER 27  359 359 SER SER A . n 
A 1 28  ASN 28  360 360 ASN ASN A . n 
A 1 29  CYS 29  361 361 CYS CYS A . n 
A 1 30  VAL 30  362 362 VAL VAL A . n 
A 1 31  ALA 31  363 363 ALA ALA A . n 
A 1 32  ASP 32  364 364 ASP ASP A . n 
A 1 33  TYR 33  365 365 TYR TYR A . n 
A 1 34  SER 34  366 366 SER SER A . n 
A 1 35  VAL 35  367 367 VAL VAL A . n 
A 1 36  LEU 36  368 368 LEU LEU A . n 
A 1 37  TYR 37  369 369 TYR TYR A . n 
A 1 38  ASN 38  370 370 ASN ASN A . n 
A 1 39  SER 39  371 371 SER SER A . n 
A 1 40  ALA 40  372 372 ALA ALA A . n 
A 1 41  SER 41  373 373 SER SER A . n 
A 1 42  PHE 42  374 374 PHE PHE A . n 
A 1 43  SER 43  375 375 SER SER A . n 
A 1 44  THR 44  376 376 THR THR A . n 
A 1 45  PHE 45  377 377 PHE PHE A . n 
A 1 46  LYS 46  378 378 LYS LYS A . n 
A 1 47  CYS 47  379 379 CYS CYS A . n 
A 1 48  TYR 48  380 380 TYR TYR A . n 
A 1 49  GLY 49  381 381 GLY GLY A . n 
A 1 50  VAL 50  382 382 VAL VAL A . n 
A 1 51  SER 51  383 383 SER SER A . n 
A 1 52  PRO 52  384 384 PRO PRO A . n 
A 1 53  THR 53  385 385 THR THR A . n 
A 1 54  LYS 54  386 386 LYS LYS A . n 
A 1 55  LEU 55  387 387 LEU LEU A . n 
A 1 56  ASN 56  388 388 ASN ASN A . n 
A 1 57  ASP 57  389 389 ASP ASP A . n 
A 1 58  LEU 58  390 390 LEU LEU A . n 
A 1 59  CYS 59  391 391 CYS CYS A . n 
A 1 60  PHE 60  392 392 PHE PHE A . n 
A 1 61  THR 61  393 393 THR THR A . n 
A 1 62  ASN 62  394 394 ASN ASN A . n 
A 1 63  VAL 63  395 395 VAL VAL A . n 
A 1 64  TYR 64  396 396 TYR TYR A . n 
A 1 65  ALA 65  397 397 ALA ALA A . n 
A 1 66  ASP 66  398 398 ASP ASP A . n 
A 1 67  SER 67  399 399 SER SER A . n 
A 1 68  PHE 68  400 400 PHE PHE A . n 
A 1 69  VAL 69  401 401 VAL VAL A . n 
A 1 70  ILE 70  402 402 ILE ILE A . n 
A 1 71  ARG 71  403 403 ARG ARG A . n 
A 1 72  GLY 72  404 404 GLY GLY A . n 
A 1 73  ASP 73  405 405 ASP ASP A . n 
A 1 74  GLU 74  406 406 GLU GLU A . n 
A 1 75  VAL 75  407 407 VAL VAL A . n 
A 1 76  ARG 76  408 408 ARG ARG A . n 
A 1 77  GLN 77  409 409 GLN GLN A . n 
A 1 78  ILE 78  410 410 ILE ILE A . n 
A 1 79  ALA 79  411 411 ALA ALA A . n 
A 1 80  PRO 80  412 412 PRO PRO A . n 
A 1 81  GLY 81  413 413 GLY GLY A . n 
A 1 82  GLN 82  414 414 GLN GLN A . n 
A 1 83  THR 83  415 415 THR THR A . n 
A 1 84  GLY 84  416 416 GLY GLY A . n 
A 1 85  LYS 85  417 417 LYS LYS A . n 
A 1 86  ILE 86  418 418 ILE ILE A . n 
A 1 87  ALA 87  419 419 ALA ALA A . n 
A 1 88  ASP 88  420 420 ASP ASP A . n 
A 1 89  TYR 89  421 421 TYR TYR A . n 
A 1 90  ASN 90  422 422 ASN ASN A . n 
A 1 91  TYR 91  423 423 TYR TYR A . n 
A 1 92  LYS 92  424 424 LYS LYS A . n 
A 1 93  LEU 93  425 425 LEU LEU A . n 
A 1 94  PRO 94  426 426 PRO PRO A . n 
A 1 95  ASP 95  427 427 ASP ASP A . n 
A 1 96  ASP 96  428 428 ASP ASP A . n 
A 1 97  PHE 97  429 429 PHE PHE A . n 
A 1 98  THR 98  430 430 THR THR A . n 
A 1 99  GLY 99  431 431 GLY GLY A . n 
A 1 100 CYS 100 432 432 CYS CYS A . n 
A 1 101 VAL 101 433 433 VAL VAL A . n 
A 1 102 ILE 102 434 434 ILE ILE A . n 
A 1 103 ALA 103 435 435 ALA ALA A . n 
A 1 104 TRP 104 436 436 TRP TRP A . n 
A 1 105 ASN 105 437 437 ASN ASN A . n 
A 1 106 SER 106 438 438 SER SER A . n 
A 1 107 ASN 107 439 439 ASN ASN A . n 
A 1 108 ASN 108 440 440 ASN ASN A . n 
A 1 109 LEU 109 441 441 LEU LEU A . n 
A 1 110 ASP 110 442 442 ASP ASP A . n 
A 1 111 SER 111 443 443 SER SER A . n 
A 1 112 LYS 112 444 444 LYS LYS A . n 
A 1 113 VAL 113 445 445 VAL VAL A . n 
A 1 114 GLY 114 446 446 GLY GLY A . n 
A 1 115 GLY 115 447 447 GLY GLY A . n 
A 1 116 ASN 116 448 448 ASN ASN A . n 
A 1 117 TYR 117 449 449 TYR TYR A . n 
A 1 118 ASN 118 450 450 ASN ASN A . n 
A 1 119 TYR 119 451 451 TYR TYR A . n 
A 1 120 LEU 120 452 452 LEU LEU A . n 
A 1 121 TYR 121 453 453 TYR TYR A . n 
A 1 122 ARG 122 454 454 ARG ARG A . n 
A 1 123 LEU 123 455 455 LEU LEU A . n 
A 1 124 PHE 124 456 456 PHE PHE A . n 
A 1 125 ARG 125 457 457 ARG ARG A . n 
A 1 126 LYS 126 458 458 LYS LYS A . n 
A 1 127 SER 127 459 459 SER SER A . n 
A 1 128 ASN 128 460 460 ASN ASN A . n 
A 1 129 LEU 129 461 461 LEU LEU A . n 
A 1 130 LYS 130 462 462 LYS LYS A . n 
A 1 131 PRO 131 463 463 PRO PRO A . n 
A 1 132 PHE 132 464 464 PHE PHE A . n 
A 1 133 GLU 133 465 465 GLU GLU A . n 
A 1 134 ARG 134 466 466 ARG ARG A . n 
A 1 135 ASP 135 467 467 ASP ASP A . n 
A 1 136 ILE 136 468 468 ILE ILE A . n 
A 1 137 SER 137 469 469 SER SER A . n 
A 1 138 THR 138 470 470 THR THR A . n 
A 1 139 GLU 139 471 471 GLU GLU A . n 
A 1 140 ILE 140 472 472 ILE ILE A . n 
A 1 141 TYR 141 473 473 TYR TYR A . n 
A 1 142 GLN 142 474 474 GLN GLN A . n 
A 1 143 ALA 143 475 475 ALA ALA A . n 
A 1 144 GLY 144 476 476 GLY GLY A . n 
A 1 145 SER 145 477 477 SER SER A . n 
A 1 146 THR 146 478 478 THR THR A . n 
A 1 147 PRO 147 479 479 PRO PRO A . n 
A 1 148 CYS 148 480 480 CYS CYS A . n 
A 1 149 ASN 149 481 481 ASN ASN A . n 
A 1 150 GLY 150 482 482 GLY GLY A . n 
A 1 151 VAL 151 483 483 VAL VAL A . n 
A 1 152 GLU 152 484 484 GLU GLU A . n 
A 1 153 GLY 153 485 485 GLY GLY A . n 
A 1 154 PHE 154 486 486 PHE PHE A . n 
A 1 155 ASN 155 487 487 ASN ASN A . n 
A 1 156 CYS 156 488 488 CYS CYS A . n 
A 1 157 TYR 157 489 489 TYR TYR A . n 
A 1 158 PHE 158 490 490 PHE PHE A . n 
A 1 159 PRO 159 491 491 PRO PRO A . n 
A 1 160 LEU 160 492 492 LEU LEU A . n 
A 1 161 GLN 161 493 493 GLN GLN A . n 
A 1 162 SER 162 494 494 SER SER A . n 
A 1 163 TYR 163 495 495 TYR TYR A . n 
A 1 164 GLY 164 496 496 GLY GLY A . n 
A 1 165 PHE 165 497 497 PHE PHE A . n 
A 1 166 GLN 166 498 498 GLN GLN A . n 
A 1 167 PRO 167 499 499 PRO PRO A . n 
A 1 168 THR 168 500 500 THR THR A . n 
A 1 169 ASN 169 501 501 ASN ASN A . n 
A 1 170 GLY 170 502 502 GLY GLY A . n 
A 1 171 VAL 171 503 503 VAL VAL A . n 
A 1 172 GLY 172 504 504 GLY GLY A . n 
A 1 173 TYR 173 505 505 TYR TYR A . n 
A 1 174 GLN 174 506 506 GLN GLN A . n 
A 1 175 PRO 175 507 507 PRO PRO A . n 
A 1 176 TYR 176 508 508 TYR TYR A . n 
A 1 177 ARG 177 509 509 ARG ARG A . n 
A 1 178 VAL 178 510 510 VAL VAL A . n 
A 1 179 VAL 179 511 511 VAL VAL A . n 
A 1 180 VAL 180 512 512 VAL VAL A . n 
A 1 181 LEU 181 513 513 LEU LEU A . n 
A 1 182 SER 182 514 514 SER SER A . n 
A 1 183 PHE 183 515 515 PHE PHE A . n 
A 1 184 GLU 184 516 516 GLU GLU A . n 
A 1 185 LEU 185 517 517 LEU LEU A . n 
A 1 186 LEU 186 518 518 LEU LEU A . n 
A 1 187 HIS 187 519 519 HIS HIS A . n 
A 1 188 ALA 188 520 520 ALA ALA A . n 
A 1 189 PRO 189 521 521 PRO PRO A . n 
A 1 190 ALA 190 522 522 ALA ALA A . n 
A 1 191 THR 191 523 523 THR THR A . n 
A 1 192 VAL 192 524 524 VAL VAL A . n 
A 1 193 CYS 193 525 525 CYS CYS A . n 
A 1 194 GLY 194 526 526 GLY GLY A . n 
A 1 195 PRO 195 527 527 PRO PRO A . n 
A 1 196 LYS 196 528 528 LYS LYS A . n 
A 1 197 LYS 197 529 ?   ?   ?   A . n 
A 1 198 SER 198 530 ?   ?   ?   A . n 
A 1 199 GLY 199 531 ?   ?   ?   A . n 
A 1 200 HIS 200 532 ?   ?   ?   A . n 
A 1 201 HIS 201 533 ?   ?   ?   A . n 
A 1 202 HIS 202 534 ?   ?   ?   A . n 
A 1 203 HIS 203 535 ?   ?   ?   A . n 
A 1 204 HIS 204 536 ?   ?   ?   A . n 
A 1 205 HIS 205 537 ?   ?   ?   A . n 
B 2 1   GLU 1   1   1   GLU GLU H . n 
B 2 2   VAL 2   2   2   VAL VAL H . n 
B 2 3   GLN 3   3   3   GLN GLN H . n 
B 2 4   LEU 4   4   4   LEU LEU H . n 
B 2 5   VAL 5   5   5   VAL VAL H . n 
B 2 6   GLN 6   6   6   GLN GLN H . n 
B 2 7   SER 7   7   7   SER SER H . n 
B 2 8   GLY 8   8   8   GLY GLY H . n 
B 2 9   ALA 9   9   9   ALA ALA H . n 
B 2 10  GLU 10  10  10  GLU GLU H . n 
B 2 11  VAL 11  11  11  VAL VAL H . n 
B 2 12  LYS 12  12  12  LYS LYS H . n 
B 2 13  LYS 13  13  13  LYS LYS H . n 
B 2 14  PRO 14  14  14  PRO PRO H . n 
B 2 15  GLY 15  15  15  GLY GLY H . n 
B 2 16  GLU 16  16  16  GLU GLU H . n 
B 2 17  SER 17  17  17  SER SER H . n 
B 2 18  LEU 18  18  18  LEU LEU H . n 
B 2 19  LYS 19  19  19  LYS LYS H . n 
B 2 20  ILE 20  20  20  ILE ILE H . n 
B 2 21  SER 21  21  21  SER SER H . n 
B 2 22  CYS 22  22  22  CYS CYS H . n 
B 2 23  LYS 23  23  23  LYS LYS H . n 
B 2 24  GLY 24  24  24  GLY GLY H . n 
B 2 25  SER 25  25  25  SER SER H . n 
B 2 26  GLY 26  26  26  GLY GLY H . n 
B 2 27  TYR 27  27  27  TYR TYR H . n 
B 2 28  SER 28  28  28  SER SER H . n 
B 2 29  PHE 29  29  29  PHE PHE H . n 
B 2 30  ILE 30  30  30  ILE ILE H . n 
B 2 31  THR 31  31  31  THR THR H . n 
B 2 32  TYR 32  32  32  TYR TYR H . n 
B 2 33  TRP 33  33  33  TRP TRP H . n 
B 2 34  ILE 34  34  34  ILE ILE H . n 
B 2 35  GLY 35  35  35  GLY GLY H . n 
B 2 36  TRP 36  36  36  TRP TRP H . n 
B 2 37  VAL 37  37  37  VAL VAL H . n 
B 2 38  ARG 38  38  38  ARG ARG H . n 
B 2 39  GLN 39  39  39  GLN GLN H . n 
B 2 40  MET 40  40  40  MET MET H . n 
B 2 41  PRO 41  41  41  PRO PRO H . n 
B 2 42  GLY 42  42  42  GLY GLY H . n 
B 2 43  LYS 43  43  43  LYS LYS H . n 
B 2 44  GLY 44  44  44  GLY GLY H . n 
B 2 45  LEU 45  45  45  LEU LEU H . n 
B 2 46  GLU 46  46  46  GLU GLU H . n 
B 2 47  TRP 47  47  47  TRP TRP H . n 
B 2 48  MET 48  48  48  MET MET H . n 
B 2 49  GLY 49  49  49  GLY GLY H . n 
B 2 50  ILE 50  50  50  ILE ILE H . n 
B 2 51  ILE 51  51  51  ILE ILE H . n 
B 2 52  TYR 52  52  52  TYR TYR H . n 
B 2 53  PRO 53  52  52  PRO PRO H A n 
B 2 54  GLY 54  53  53  GLY GLY H . n 
B 2 55  ASP 55  54  54  ASP ASP H . n 
B 2 56  SER 56  55  55  SER SER H . n 
B 2 57  ASP 57  56  56  ASP ASP H . n 
B 2 58  THR 58  57  57  THR THR H . n 
B 2 59  ARG 59  58  58  ARG ARG H . n 
B 2 60  TYR 60  59  59  TYR TYR H . n 
B 2 61  SER 61  60  60  SER SER H . n 
B 2 62  PRO 62  61  61  PRO PRO H . n 
B 2 63  SER 63  62  62  SER SER H . n 
B 2 64  PHE 64  63  63  PHE PHE H . n 
B 2 65  GLN 65  64  64  GLN GLN H . n 
B 2 66  GLY 66  65  65  GLY GLY H . n 
B 2 67  GLN 67  66  66  GLN GLN H . n 
B 2 68  VAL 68  67  67  VAL VAL H . n 
B 2 69  THR 69  68  68  THR THR H . n 
B 2 70  ILE 70  69  69  ILE ILE H . n 
B 2 71  SER 71  70  70  SER SER H . n 
B 2 72  ALA 72  71  71  ALA ALA H . n 
B 2 73  ASP 73  72  72  ASP ASP H . n 
B 2 74  LYS 74  73  73  LYS LYS H . n 
B 2 75  SER 75  74  74  SER SER H . n 
B 2 76  ILE 76  75  75  ILE ILE H . n 
B 2 77  ASN 77  76  76  ASN ASN H . n 
B 2 78  THR 78  77  77  THR THR H . n 
B 2 79  ALA 79  78  78  ALA ALA H . n 
B 2 80  TYR 80  79  79  TYR TYR H . n 
B 2 81  LEU 81  80  80  LEU LEU H . n 
B 2 82  GLN 82  81  81  GLN GLN H . n 
B 2 83  TRP 83  82  82  TRP TRP H . n 
B 2 84  SER 84  82  82  SER SER H A n 
B 2 85  SER 85  82  82  SER SER H B n 
B 2 86  LEU 86  82  82  LEU LEU H C n 
B 2 87  LYS 87  83  83  LYS LYS H . n 
B 2 88  ALA 88  84  84  ALA ALA H . n 
B 2 89  SER 89  85  85  SER SER H . n 
B 2 90  ASP 90  86  86  ASP ASP H . n 
B 2 91  THR 91  87  87  THR THR H . n 
B 2 92  ALA 92  88  88  ALA ALA H . n 
B 2 93  MET 93  89  89  MET MET H . n 
B 2 94  TYR 94  90  90  TYR TYR H . n 
B 2 95  TYR 95  91  91  TYR TYR H . n 
B 2 96  CYS 96  92  92  CYS CYS H . n 
B 2 97  ALA 97  93  93  ALA ALA H . n 
B 2 98  GLY 98  94  94  GLY GLY H . n 
B 2 99  SER 99  95  95  SER SER H . n 
B 2 100 SER 100 96  96  SER SER H . n 
B 2 101 GLY 101 97  97  GLY GLY H . n 
B 2 102 ILE 102 98  98  ILE ILE H . n 
B 2 103 SER 103 99  99  SER SER H . n 
B 2 104 THR 104 100 100 THR THR H . n 
B 2 105 PRO 105 100 100 PRO PRO H A n 
B 2 106 MET 106 100 100 MET MET H B n 
B 2 107 ASP 107 101 101 ASP ASP H . n 
B 2 108 VAL 108 102 102 VAL VAL H . n 
B 2 109 TRP 109 103 103 TRP TRP H . n 
B 2 110 GLY 110 104 104 GLY GLY H . n 
B 2 111 ARG 111 105 105 ARG ARG H . n 
B 2 112 GLY 112 106 106 GLY GLY H . n 
B 2 113 THR 113 107 107 THR THR H . n 
B 2 114 THR 114 108 108 THR THR H . n 
B 2 115 VAL 115 109 109 VAL VAL H . n 
B 2 116 THR 116 110 110 THR THR H . n 
B 2 117 VAL 117 111 111 VAL VAL H . n 
B 2 118 SER 118 112 112 SER SER H . n 
B 2 119 SER 119 113 113 SER SER H . n 
B 2 120 ALA 120 114 114 ALA ALA H . n 
B 2 121 SER 121 115 115 SER SER H . n 
B 2 122 THR 122 116 116 THR THR H . n 
B 2 123 LYS 123 117 117 LYS LYS H . n 
B 2 124 GLY 124 118 118 GLY GLY H . n 
B 2 125 PRO 125 119 119 PRO PRO H . n 
B 2 126 SER 126 120 120 SER SER H . n 
B 2 127 VAL 127 121 121 VAL VAL H . n 
B 2 128 PHE 128 122 122 PHE PHE H . n 
B 2 129 PRO 129 123 123 PRO PRO H . n 
B 2 130 LEU 130 124 124 LEU LEU H . n 
B 2 131 ALA 131 125 125 ALA ALA H . n 
B 2 132 PRO 132 126 126 PRO PRO H . n 
B 2 133 SER 133 127 127 SER SER H . n 
B 2 134 SER 134 128 128 SER SER H . n 
B 2 135 LYS 135 129 ?   ?   ?   H . n 
B 2 136 SER 136 130 ?   ?   ?   H . n 
B 2 137 THR 137 131 ?   ?   ?   H . n 
B 2 138 SER 138 132 132 SER SER H . n 
B 2 139 GLY 139 133 133 GLY GLY H . n 
B 2 140 GLY 140 134 134 GLY GLY H . n 
B 2 141 THR 141 135 135 THR THR H . n 
B 2 142 ALA 142 136 136 ALA ALA H . n 
B 2 143 ALA 143 137 137 ALA ALA H . n 
B 2 144 LEU 144 138 138 LEU LEU H . n 
B 2 145 GLY 145 139 139 GLY GLY H . n 
B 2 146 CYS 146 140 140 CYS CYS H . n 
B 2 147 LEU 147 141 141 LEU LEU H . n 
B 2 148 VAL 148 142 142 VAL VAL H . n 
B 2 149 LYS 149 143 143 LYS LYS H . n 
B 2 150 ASP 150 144 144 ASP ASP H . n 
B 2 151 TYR 151 145 145 TYR TYR H . n 
B 2 152 PHE 152 146 146 PHE PHE H . n 
B 2 153 PRO 153 147 147 PRO PRO H . n 
B 2 154 GLU 154 148 148 GLU GLU H . n 
B 2 155 PRO 155 149 149 PRO PRO H . n 
B 2 156 VAL 156 150 150 VAL VAL H . n 
B 2 157 THR 157 151 151 THR THR H . n 
B 2 158 VAL 158 152 152 VAL VAL H . n 
B 2 159 SER 159 153 153 SER SER H . n 
B 2 160 TRP 160 154 154 TRP TRP H . n 
B 2 161 ASN 161 155 155 ASN ASN H . n 
B 2 162 SER 162 156 156 SER SER H . n 
B 2 163 GLY 163 157 157 GLY GLY H . n 
B 2 164 ALA 164 158 158 ALA ALA H . n 
B 2 165 LEU 165 159 159 LEU LEU H . n 
B 2 166 THR 166 160 160 THR THR H . n 
B 2 167 SER 167 161 161 SER SER H . n 
B 2 168 GLY 168 162 162 GLY GLY H . n 
B 2 169 VAL 169 163 163 VAL VAL H . n 
B 2 170 HIS 170 164 164 HIS HIS H . n 
B 2 171 THR 171 165 165 THR THR H . n 
B 2 172 PHE 172 166 166 PHE PHE H . n 
B 2 173 PRO 173 167 167 PRO PRO H . n 
B 2 174 ALA 174 168 168 ALA ALA H . n 
B 2 175 VAL 175 169 169 VAL VAL H . n 
B 2 176 LEU 176 170 170 LEU LEU H . n 
B 2 177 GLN 177 171 171 GLN GLN H . n 
B 2 178 SER 178 172 172 SER SER H . n 
B 2 179 SER 179 173 173 SER SER H . n 
B 2 180 GLY 180 174 174 GLY GLY H . n 
B 2 181 LEU 181 175 175 LEU LEU H . n 
B 2 182 TYR 182 176 176 TYR TYR H . n 
B 2 183 SER 183 177 177 SER SER H . n 
B 2 184 LEU 184 178 178 LEU LEU H . n 
B 2 185 SER 185 179 179 SER SER H . n 
B 2 186 SER 186 180 180 SER SER H . n 
B 2 187 VAL 187 181 181 VAL VAL H . n 
B 2 188 VAL 188 182 182 VAL VAL H . n 
B 2 189 THR 189 183 183 THR THR H . n 
B 2 190 VAL 190 184 184 VAL VAL H . n 
B 2 191 PRO 191 185 185 PRO PRO H . n 
B 2 192 SER 192 186 186 SER SER H . n 
B 2 193 SER 193 187 187 SER SER H . n 
B 2 194 SER 194 188 188 SER SER H . n 
B 2 195 LEU 195 189 189 LEU LEU H . n 
B 2 196 GLY 196 190 190 GLY GLY H . n 
B 2 197 THR 197 191 191 THR THR H . n 
B 2 198 GLN 198 192 192 GLN GLN H . n 
B 2 199 THR 199 193 193 THR THR H . n 
B 2 200 TYR 200 194 194 TYR TYR H . n 
B 2 201 ILE 201 195 195 ILE ILE H . n 
B 2 202 CYS 202 196 196 CYS CYS H . n 
B 2 203 ASN 203 197 197 ASN ASN H . n 
B 2 204 VAL 204 198 198 VAL VAL H . n 
B 2 205 ASN 205 199 199 ASN ASN H . n 
B 2 206 HIS 206 200 200 HIS HIS H . n 
B 2 207 LYS 207 201 201 LYS LYS H . n 
B 2 208 PRO 208 202 202 PRO PRO H . n 
B 2 209 SER 209 203 203 SER SER H . n 
B 2 210 ASN 210 204 204 ASN ASN H . n 
B 2 211 THR 211 205 205 THR THR H . n 
B 2 212 LYS 212 206 206 LYS LYS H . n 
B 2 213 VAL 213 207 207 VAL VAL H . n 
B 2 214 ASP 214 208 208 ASP ASP H . n 
B 2 215 LYS 215 209 209 LYS LYS H . n 
B 2 216 LYS 216 210 210 LYS LYS H . n 
B 2 217 VAL 217 211 211 VAL VAL H . n 
B 2 218 GLU 218 212 212 GLU GLU H . n 
B 2 219 PRO 219 213 213 PRO PRO H . n 
B 2 220 LYS 220 214 ?   ?   ?   H . n 
B 2 221 SER 221 215 ?   ?   ?   H . n 
B 2 222 CYS 222 216 ?   ?   ?   H . n 
C 3 1   GLN 1   1   1   GLN GLN F . n 
C 3 2   VAL 2   2   2   VAL VAL F . n 
C 3 3   GLN 3   3   3   GLN GLN F . n 
C 3 4   LEU 4   4   4   LEU LEU F . n 
C 3 5   VAL 5   5   5   VAL VAL F . n 
C 3 6   GLU 6   6   6   GLU GLU F . n 
C 3 7   SER 7   7   7   SER SER F . n 
C 3 8   GLY 8   8   8   GLY GLY F . n 
C 3 9   GLY 9   9   9   GLY GLY F . n 
C 3 10  GLY 10  10  10  GLY GLY F . n 
C 3 11  LEU 11  11  11  LEU LEU F . n 
C 3 12  ILE 12  12  12  ILE ILE F . n 
C 3 13  GLN 13  13  13  GLN GLN F . n 
C 3 14  PRO 14  14  14  PRO PRO F . n 
C 3 15  GLY 15  15  15  GLY GLY F . n 
C 3 16  GLY 16  16  16  GLY GLY F . n 
C 3 17  SER 17  17  17  SER SER F . n 
C 3 18  LEU 18  18  18  LEU LEU F . n 
C 3 19  ARG 19  19  19  ARG ARG F . n 
C 3 20  LEU 20  20  20  LEU LEU F . n 
C 3 21  SER 21  21  21  SER SER F . n 
C 3 22  CYS 22  22  22  CYS CYS F . n 
C 3 23  ALA 23  23  23  ALA ALA F . n 
C 3 24  ALA 24  24  24  ALA ALA F . n 
C 3 25  SER 25  25  25  SER SER F . n 
C 3 26  GLY 26  26  26  GLY GLY F . n 
C 3 27  PHE 27  27  27  PHE PHE F . n 
C 3 28  THR 28  28  28  THR THR F . n 
C 3 29  VAL 29  29  29  VAL VAL F . n 
C 3 30  SER 30  30  30  SER SER F . n 
C 3 31  SER 31  31  31  SER SER F . n 
C 3 32  ASN 32  32  32  ASN ASN F . n 
C 3 33  TYR 33  33  33  TYR TYR F . n 
C 3 34  MET 34  34  34  MET MET F . n 
C 3 35  SER 35  35  35  SER SER F . n 
C 3 36  TRP 36  36  36  TRP TRP F . n 
C 3 37  VAL 37  37  37  VAL VAL F . n 
C 3 38  ARG 38  38  38  ARG ARG F . n 
C 3 39  GLN 39  39  39  GLN GLN F . n 
C 3 40  ALA 40  40  40  ALA ALA F . n 
C 3 41  PRO 41  41  41  PRO PRO F . n 
C 3 42  GLY 42  42  42  GLY GLY F . n 
C 3 43  LYS 43  43  43  LYS LYS F . n 
C 3 44  GLY 44  44  44  GLY GLY F . n 
C 3 45  LEU 45  45  45  LEU LEU F . n 
C 3 46  GLU 46  46  46  GLU GLU F . n 
C 3 47  TRP 47  47  47  TRP TRP F . n 
C 3 48  VAL 48  48  48  VAL VAL F . n 
C 3 49  SER 49  49  49  SER SER F . n 
C 3 50  VAL 50  50  50  VAL VAL F . n 
C 3 51  ILE 51  51  51  ILE ILE F . n 
C 3 52  TYR 52  52  52  TYR TYR F . n 
C 3 53  SER 53  53  53  SER SER F . n 
C 3 54  GLY 54  54  54  GLY GLY F . n 
C 3 55  GLY 55  55  55  GLY GLY F . n 
C 3 56  SER 56  56  56  SER SER F . n 
C 3 57  THR 57  57  57  THR THR F . n 
C 3 58  PHE 58  58  58  PHE PHE F . n 
C 3 59  TYR 59  59  59  TYR TYR F . n 
C 3 60  ALA 60  60  60  ALA ALA F . n 
C 3 61  ASP 61  61  61  ASP ASP F . n 
C 3 62  SER 62  62  62  SER SER F . n 
C 3 63  VAL 63  63  63  VAL VAL F . n 
C 3 64  LYS 64  64  64  LYS LYS F . n 
C 3 65  GLY 65  65  65  GLY GLY F . n 
C 3 66  ARG 66  66  66  ARG ARG F . n 
C 3 67  PHE 67  67  67  PHE PHE F . n 
C 3 68  THR 68  68  68  THR THR F . n 
C 3 69  ILE 69  69  69  ILE ILE F . n 
C 3 70  SER 70  70  70  SER SER F . n 
C 3 71  ARG 71  71  71  ARG ARG F . n 
C 3 72  ASP 72  72  72  ASP ASP F . n 
C 3 73  ASN 73  73  73  ASN ASN F . n 
C 3 74  SER 74  74  74  SER SER F . n 
C 3 75  LYS 75  75  75  LYS LYS F . n 
C 3 76  SER 76  76  76  SER SER F . n 
C 3 77  THR 77  77  77  THR THR F . n 
C 3 78  LEU 78  78  78  LEU LEU F . n 
C 3 79  TYR 79  79  79  TYR TYR F . n 
C 3 80  LEU 80  80  80  LEU LEU F . n 
C 3 81  GLN 81  81  81  GLN GLN F . n 
C 3 82  MET 82  82  82  MET MET F . n 
C 3 83  ASN 83  82  82  ASN ASN F A n 
C 3 84  SER 84  82  82  SER SER F B n 
C 3 85  LEU 85  82  82  LEU LEU F C n 
C 3 86  ARG 86  83  83  ARG ARG F . n 
C 3 87  VAL 87  84  84  VAL VAL F . n 
C 3 88  GLU 88  85  85  GLU GLU F . n 
C 3 89  ASP 89  86  86  ASP ASP F . n 
C 3 90  THR 90  87  87  THR THR F . n 
C 3 91  ALA 91  88  88  ALA ALA F . n 
C 3 92  VAL 92  89  89  VAL VAL F . n 
C 3 93  TYR 93  90  90  TYR TYR F . n 
C 3 94  TYR 94  91  91  TYR TYR F . n 
C 3 95  CYS 95  92  92  CYS CYS F . n 
C 3 96  ALA 96  93  93  ALA ALA F . n 
C 3 97  ARG 97  94  94  ARG ARG F . n 
C 3 98  ASP 98  95  95  ASP ASP F . n 
C 3 99  PHE 99  96  96  PHE PHE F . n 
C 3 100 GLY 100 97  97  GLY GLY F . n 
C 3 101 ASP 101 98  98  ASP ASP F . n 
C 3 102 PHE 102 99  99  PHE PHE F . n 
C 3 103 TYR 103 100 100 TYR TYR F . n 
C 3 104 PHE 104 100 100 PHE PHE F A n 
C 3 105 ASP 105 101 101 ASP ASP F . n 
C 3 106 TYR 106 102 102 TYR TYR F . n 
C 3 107 TRP 107 103 103 TRP TRP F . n 
C 3 108 GLY 108 104 104 GLY GLY F . n 
C 3 109 GLN 109 105 105 GLN GLN F . n 
C 3 110 GLY 110 106 106 GLY GLY F . n 
C 3 111 THR 111 107 107 THR THR F . n 
C 3 112 LEU 112 108 108 LEU LEU F . n 
C 3 113 VAL 113 109 109 VAL VAL F . n 
C 3 114 THR 114 110 110 THR THR F . n 
C 3 115 VAL 115 111 111 VAL VAL F . n 
C 3 116 SER 116 112 112 SER SER F . n 
C 3 117 SER 117 113 113 SER SER F . n 
C 3 118 ALA 118 114 114 ALA ALA F . n 
C 3 119 SER 119 115 115 SER SER F . n 
C 3 120 THR 120 116 116 THR THR F . n 
C 3 121 LYS 121 117 117 LYS LYS F . n 
C 3 122 GLY 122 118 118 GLY GLY F . n 
C 3 123 PRO 123 119 119 PRO PRO F . n 
C 3 124 SER 124 120 120 SER SER F . n 
C 3 125 VAL 125 121 121 VAL VAL F . n 
C 3 126 PHE 126 122 122 PHE PHE F . n 
C 3 127 PRO 127 123 123 PRO PRO F . n 
C 3 128 LEU 128 124 124 LEU LEU F . n 
C 3 129 ALA 129 125 125 ALA ALA F . n 
C 3 130 PRO 130 126 126 PRO PRO F . n 
C 3 131 SER 131 127 127 SER SER F . n 
C 3 132 SER 132 128 128 SER SER F . n 
C 3 133 LYS 133 129 ?   ?   ?   F . n 
C 3 134 SER 134 130 ?   ?   ?   F . n 
C 3 135 THR 135 131 ?   ?   ?   F . n 
C 3 136 SER 136 132 ?   ?   ?   F . n 
C 3 137 GLY 137 133 ?   ?   ?   F . n 
C 3 138 GLY 138 134 ?   ?   ?   F . n 
C 3 139 THR 139 135 135 THR THR F . n 
C 3 140 ALA 140 136 136 ALA ALA F . n 
C 3 141 ALA 141 137 137 ALA ALA F . n 
C 3 142 LEU 142 138 138 LEU LEU F . n 
C 3 143 GLY 143 139 139 GLY GLY F . n 
C 3 144 CYS 144 140 140 CYS CYS F . n 
C 3 145 LEU 145 141 141 LEU LEU F . n 
C 3 146 VAL 146 142 142 VAL VAL F . n 
C 3 147 LYS 147 143 143 LYS LYS F . n 
C 3 148 ASP 148 144 144 ASP ASP F . n 
C 3 149 TYR 149 145 145 TYR TYR F . n 
C 3 150 PHE 150 146 146 PHE PHE F . n 
C 3 151 PRO 151 147 147 PRO PRO F . n 
C 3 152 GLU 152 148 148 GLU GLU F . n 
C 3 153 PRO 153 149 149 PRO PRO F . n 
C 3 154 VAL 154 150 150 VAL VAL F . n 
C 3 155 THR 155 151 151 THR THR F . n 
C 3 156 VAL 156 152 152 VAL VAL F . n 
C 3 157 SER 157 153 153 SER SER F . n 
C 3 158 TRP 158 154 154 TRP TRP F . n 
C 3 159 ASN 159 155 155 ASN ASN F . n 
C 3 160 SER 160 156 156 SER SER F . n 
C 3 161 GLY 161 157 157 GLY GLY F . n 
C 3 162 ALA 162 158 158 ALA ALA F . n 
C 3 163 LEU 163 159 159 LEU LEU F . n 
C 3 164 THR 164 160 160 THR THR F . n 
C 3 165 SER 165 161 161 SER SER F . n 
C 3 166 GLY 166 162 162 GLY GLY F . n 
C 3 167 VAL 167 163 163 VAL VAL F . n 
C 3 168 HIS 168 164 164 HIS HIS F . n 
C 3 169 THR 169 165 165 THR THR F . n 
C 3 170 PHE 170 166 166 PHE PHE F . n 
C 3 171 PRO 171 167 167 PRO PRO F . n 
C 3 172 ALA 172 168 168 ALA ALA F . n 
C 3 173 VAL 173 169 169 VAL VAL F . n 
C 3 174 LEU 174 170 170 LEU LEU F . n 
C 3 175 GLN 175 171 171 GLN GLN F . n 
C 3 176 SER 176 172 172 SER SER F . n 
C 3 177 SER 177 173 173 SER SER F . n 
C 3 178 GLY 178 174 174 GLY GLY F . n 
C 3 179 LEU 179 175 175 LEU LEU F . n 
C 3 180 TYR 180 176 176 TYR TYR F . n 
C 3 181 SER 181 177 177 SER SER F . n 
C 3 182 LEU 182 178 178 LEU LEU F . n 
C 3 183 SER 183 179 179 SER SER F . n 
C 3 184 SER 184 180 180 SER SER F . n 
C 3 185 VAL 185 181 181 VAL VAL F . n 
C 3 186 VAL 186 182 182 VAL VAL F . n 
C 3 187 THR 187 183 183 THR THR F . n 
C 3 188 VAL 188 184 184 VAL VAL F . n 
C 3 189 PRO 189 185 185 PRO PRO F . n 
C 3 190 SER 190 186 186 SER SER F . n 
C 3 191 SER 191 187 187 SER SER F . n 
C 3 192 SER 192 188 188 SER SER F . n 
C 3 193 LEU 193 189 189 LEU LEU F . n 
C 3 194 GLY 194 190 190 GLY GLY F . n 
C 3 195 THR 195 191 191 THR THR F . n 
C 3 196 GLN 196 192 192 GLN GLN F . n 
C 3 197 THR 197 193 193 THR THR F . n 
C 3 198 TYR 198 194 194 TYR TYR F . n 
C 3 199 ILE 199 195 195 ILE ILE F . n 
C 3 200 CYS 200 196 196 CYS CYS F . n 
C 3 201 ASN 201 197 197 ASN ASN F . n 
C 3 202 VAL 202 198 198 VAL VAL F . n 
C 3 203 ASN 203 199 199 ASN ASN F . n 
C 3 204 HIS 204 200 200 HIS HIS F . n 
C 3 205 LYS 205 201 201 LYS LYS F . n 
C 3 206 PRO 206 202 202 PRO PRO F . n 
C 3 207 SER 207 203 203 SER SER F . n 
C 3 208 ASN 208 204 204 ASN ASN F . n 
C 3 209 THR 209 205 205 THR THR F . n 
C 3 210 LYS 210 206 206 LYS LYS F . n 
C 3 211 VAL 211 207 207 VAL VAL F . n 
C 3 212 ASP 212 208 208 ASP ASP F . n 
C 3 213 LYS 213 209 209 LYS LYS F . n 
C 3 214 LYS 214 210 210 LYS LYS F . n 
C 3 215 VAL 215 211 211 VAL VAL F . n 
C 3 216 GLU 216 212 212 GLU GLU F . n 
C 3 217 PRO 217 213 213 PRO PRO F . n 
C 3 218 LYS 218 214 214 LYS LYS F . n 
C 3 219 SER 219 215 ?   ?   ?   F . n 
C 3 220 CYS 220 216 ?   ?   ?   F . n 
D 4 1   ASP 1   1   1   ASP ASP L . n 
D 4 2   ILE 2   2   2   ILE ILE L . n 
D 4 3   VAL 3   3   3   VAL VAL L . n 
D 4 4   MET 4   4   4   MET MET L . n 
D 4 5   THR 5   5   5   THR THR L . n 
D 4 6   GLN 6   6   6   GLN GLN L . n 
D 4 7   SER 7   7   7   SER SER L . n 
D 4 8   PRO 8   8   8   PRO PRO L . n 
D 4 9   ASP 9   9   9   ASP ASP L . n 
D 4 10  SER 10  10  10  SER SER L . n 
D 4 11  LEU 11  11  11  LEU LEU L . n 
D 4 12  ALA 12  12  12  ALA ALA L . n 
D 4 13  VAL 13  13  13  VAL VAL L . n 
D 4 14  SER 14  14  14  SER SER L . n 
D 4 15  LEU 15  15  15  LEU LEU L . n 
D 4 16  GLY 16  16  16  GLY GLY L . n 
D 4 17  GLU 17  17  17  GLU GLU L . n 
D 4 18  ARG 18  18  18  ARG ARG L . n 
D 4 19  ALA 19  19  19  ALA ALA L . n 
D 4 20  THR 20  20  20  THR THR L . n 
D 4 21  ILE 21  21  21  ILE ILE L . n 
D 4 22  ASN 22  22  22  ASN ASN L . n 
D 4 23  CYS 23  23  23  CYS CYS L . n 
D 4 24  LYS 24  24  24  LYS LYS L . n 
D 4 25  SER 25  25  25  SER SER L . n 
D 4 26  SER 26  26  26  SER SER L . n 
D 4 27  GLN 27  27  27  GLN GLN L . n 
D 4 28  SER 28  27  27  SER SER L A n 
D 4 29  VAL 29  27  27  VAL VAL L B n 
D 4 30  LEU 30  27  27  LEU LEU L C n 
D 4 31  TYR 31  27  27  TYR TYR L D n 
D 4 32  SER 32  27  27  SER SER L E n 
D 4 33  SER 33  27  27  SER SER L F n 
D 4 34  PHE 34  28  28  PHE PHE L . n 
D 4 35  ASN 35  29  29  ASN ASN L . n 
D 4 36  LYS 36  30  30  LYS LYS L . n 
D 4 37  ASP 37  31  31  ASP ASP L . n 
D 4 38  TYR 38  32  32  TYR TYR L . n 
D 4 39  LEU 39  33  33  LEU LEU L . n 
D 4 40  ALA 40  34  34  ALA ALA L . n 
D 4 41  TRP 41  35  35  TRP TRP L . n 
D 4 42  TYR 42  36  36  TYR TYR L . n 
D 4 43  GLN 43  37  37  GLN GLN L . n 
D 4 44  GLN 44  38  38  GLN GLN L . n 
D 4 45  LYS 45  39  39  LYS LYS L . n 
D 4 46  PRO 46  40  40  PRO PRO L . n 
D 4 47  GLY 47  41  41  GLY GLY L . n 
D 4 48  GLN 48  42  42  GLN GLN L . n 
D 4 49  PRO 49  43  43  PRO PRO L . n 
D 4 50  PRO 50  44  44  PRO PRO L . n 
D 4 51  LYS 51  45  45  LYS LYS L . n 
D 4 52  LEU 52  46  46  LEU LEU L . n 
D 4 53  LEU 53  47  47  LEU LEU L . n 
D 4 54  ILE 54  48  48  ILE ILE L . n 
D 4 55  TYR 55  49  49  TYR TYR L . n 
D 4 56  TRP 56  50  50  TRP TRP L . n 
D 4 57  ALA 57  51  51  ALA ALA L . n 
D 4 58  SER 58  52  52  SER SER L . n 
D 4 59  ILE 59  53  53  ILE ILE L . n 
D 4 60  ARG 60  54  54  ARG ARG L . n 
D 4 61  GLU 61  55  55  GLU GLU L . n 
D 4 62  SER 62  56  56  SER SER L . n 
D 4 63  GLY 63  57  57  GLY GLY L . n 
D 4 64  VAL 64  58  58  VAL VAL L . n 
D 4 65  PRO 65  59  59  PRO PRO L . n 
D 4 66  ASP 66  60  60  ASP ASP L . n 
D 4 67  ARG 67  61  61  ARG ARG L . n 
D 4 68  PHE 68  62  62  PHE PHE L . n 
D 4 69  SER 69  63  63  SER SER L . n 
D 4 70  GLY 70  64  64  GLY GLY L . n 
D 4 71  SER 71  65  65  SER SER L . n 
D 4 72  GLY 72  66  66  GLY GLY L . n 
D 4 73  SER 73  67  67  SER SER L . n 
D 4 74  GLY 74  68  68  GLY GLY L . n 
D 4 75  THR 75  69  69  THR THR L . n 
D 4 76  ASP 76  70  70  ASP ASP L . n 
D 4 77  PHE 77  71  71  PHE PHE L . n 
D 4 78  THR 78  72  72  THR THR L . n 
D 4 79  LEU 79  73  73  LEU LEU L . n 
D 4 80  THR 80  74  74  THR THR L . n 
D 4 81  ILE 81  75  75  ILE ILE L . n 
D 4 82  SER 82  76  76  SER SER L . n 
D 4 83  GLY 83  77  77  GLY GLY L . n 
D 4 84  LEU 84  78  78  LEU LEU L . n 
D 4 85  GLN 85  79  79  GLN GLN L . n 
D 4 86  ALA 86  80  80  ALA ALA L . n 
D 4 87  GLU 87  81  81  GLU GLU L . n 
D 4 88  ASP 88  82  82  ASP ASP L . n 
D 4 89  VAL 89  83  83  VAL VAL L . n 
D 4 90  ALA 90  84  84  ALA ALA L . n 
D 4 91  VAL 91  85  85  VAL VAL L . n 
D 4 92  TYR 92  86  86  TYR TYR L . n 
D 4 93  TYR 93  87  87  TYR TYR L . n 
D 4 94  CYS 94  88  88  CYS CYS L . n 
D 4 95  GLN 95  89  89  GLN GLN L . n 
D 4 96  GLN 96  90  90  GLN GLN L . n 
D 4 97  TYR 97  91  91  TYR TYR L . n 
D 4 98  SER 98  92  92  SER SER L . n 
D 4 99  ARG 99  93  93  ARG ARG L . n 
D 4 100 THR 100 94  94  THR THR L . n 
D 4 101 PRO 101 95  95  PRO PRO L . n 
D 4 102 TYR 102 96  96  TYR TYR L . n 
D 4 103 THR 103 97  97  THR THR L . n 
D 4 104 PHE 104 98  98  PHE PHE L . n 
D 4 105 GLY 105 99  99  GLY GLY L . n 
D 4 106 GLN 106 100 100 GLN GLN L . n 
D 4 107 GLY 107 101 101 GLY GLY L . n 
D 4 108 THR 108 102 102 THR THR L . n 
D 4 109 LYS 109 103 103 LYS LYS L . n 
D 4 110 LEU 110 104 104 LEU LEU L . n 
D 4 111 GLU 111 105 105 GLU GLU L . n 
D 4 112 ILE 112 106 106 ILE ILE L . n 
D 4 113 LYS 113 107 107 LYS LYS L . n 
D 4 114 ARG 114 108 108 ARG ARG L . n 
D 4 115 THR 115 109 109 THR THR L . n 
D 4 116 VAL 116 110 110 VAL VAL L . n 
D 4 117 ALA 117 111 111 ALA ALA L . n 
D 4 118 ALA 118 112 112 ALA ALA L . n 
D 4 119 PRO 119 113 113 PRO PRO L . n 
D 4 120 SER 120 114 114 SER SER L . n 
D 4 121 VAL 121 115 115 VAL VAL L . n 
D 4 122 PHE 122 116 116 PHE PHE L . n 
D 4 123 ILE 123 117 117 ILE ILE L . n 
D 4 124 PHE 124 118 118 PHE PHE L . n 
D 4 125 PRO 125 119 119 PRO PRO L . n 
D 4 126 PRO 126 120 120 PRO PRO L . n 
D 4 127 SER 127 121 121 SER SER L . n 
D 4 128 ASP 128 122 122 ASP ASP L . n 
D 4 129 GLU 129 123 123 GLU GLU L . n 
D 4 130 GLN 130 124 124 GLN GLN L . n 
D 4 131 LEU 131 125 125 LEU LEU L . n 
D 4 132 LYS 132 126 126 LYS LYS L . n 
D 4 133 SER 133 127 127 SER SER L . n 
D 4 134 GLY 134 128 128 GLY GLY L . n 
D 4 135 THR 135 129 129 THR THR L . n 
D 4 136 ALA 136 130 130 ALA ALA L . n 
D 4 137 SER 137 131 131 SER SER L . n 
D 4 138 VAL 138 132 132 VAL VAL L . n 
D 4 139 VAL 139 133 133 VAL VAL L . n 
D 4 140 CYS 140 134 134 CYS CYS L . n 
D 4 141 LEU 141 135 135 LEU LEU L . n 
D 4 142 LEU 142 136 136 LEU LEU L . n 
D 4 143 ASN 143 137 137 ASN ASN L . n 
D 4 144 ASN 144 138 138 ASN ASN L . n 
D 4 145 PHE 145 139 139 PHE PHE L . n 
D 4 146 TYR 146 140 140 TYR TYR L . n 
D 4 147 PRO 147 141 141 PRO PRO L . n 
D 4 148 ARG 148 142 142 ARG ARG L . n 
D 4 149 GLU 149 143 143 GLU GLU L . n 
D 4 150 ALA 150 144 144 ALA ALA L . n 
D 4 151 LYS 151 145 145 LYS LYS L . n 
D 4 152 VAL 152 146 146 VAL VAL L . n 
D 4 153 GLN 153 147 147 GLN GLN L . n 
D 4 154 TRP 154 148 148 TRP TRP L . n 
D 4 155 LYS 155 149 149 LYS LYS L . n 
D 4 156 VAL 156 150 150 VAL VAL L . n 
D 4 157 ASP 157 151 151 ASP ASP L . n 
D 4 158 ASN 158 152 152 ASN ASN L . n 
D 4 159 ALA 159 153 153 ALA ALA L . n 
D 4 160 LEU 160 154 154 LEU LEU L . n 
D 4 161 GLN 161 155 155 GLN GLN L . n 
D 4 162 SER 162 156 156 SER SER L . n 
D 4 163 GLY 163 157 157 GLY GLY L . n 
D 4 164 ASN 164 158 158 ASN ASN L . n 
D 4 165 SER 165 159 159 SER SER L . n 
D 4 166 GLN 166 160 160 GLN GLN L . n 
D 4 167 GLU 167 161 161 GLU GLU L . n 
D 4 168 SER 168 162 162 SER SER L . n 
D 4 169 VAL 169 163 163 VAL VAL L . n 
D 4 170 THR 170 164 164 THR THR L . n 
D 4 171 GLU 171 165 165 GLU GLU L . n 
D 4 172 GLN 172 166 166 GLN GLN L . n 
D 4 173 ASP 173 167 167 ASP ASP L . n 
D 4 174 SER 174 168 168 SER SER L . n 
D 4 175 LYS 175 169 169 LYS LYS L . n 
D 4 176 ASP 176 170 170 ASP ASP L . n 
D 4 177 SER 177 171 171 SER SER L . n 
D 4 178 THR 178 172 172 THR THR L . n 
D 4 179 TYR 179 173 173 TYR TYR L . n 
D 4 180 SER 180 174 174 SER SER L . n 
D 4 181 LEU 181 175 175 LEU LEU L . n 
D 4 182 SER 182 176 176 SER SER L . n 
D 4 183 SER 183 177 177 SER SER L . n 
D 4 184 THR 184 178 178 THR THR L . n 
D 4 185 LEU 185 179 179 LEU LEU L . n 
D 4 186 THR 186 180 180 THR THR L . n 
D 4 187 LEU 187 181 181 LEU LEU L . n 
D 4 188 SER 188 182 182 SER SER L . n 
D 4 189 LYS 189 183 183 LYS LYS L . n 
D 4 190 ALA 190 184 184 ALA ALA L . n 
D 4 191 ASP 191 185 185 ASP ASP L . n 
D 4 192 TYR 192 186 186 TYR TYR L . n 
D 4 193 GLU 193 187 187 GLU GLU L . n 
D 4 194 LYS 194 188 188 LYS LYS L . n 
D 4 195 HIS 195 189 189 HIS HIS L . n 
D 4 196 LYS 196 190 190 LYS LYS L . n 
D 4 197 VAL 197 191 191 VAL VAL L . n 
D 4 198 TYR 198 192 192 TYR TYR L . n 
D 4 199 ALA 199 193 193 ALA ALA L . n 
D 4 200 CYS 200 194 194 CYS CYS L . n 
D 4 201 GLU 201 195 195 GLU GLU L . n 
D 4 202 VAL 202 196 196 VAL VAL L . n 
D 4 203 THR 203 197 197 THR THR L . n 
D 4 204 HIS 204 198 198 HIS HIS L . n 
D 4 205 GLN 205 199 199 GLN GLN L . n 
D 4 206 GLY 206 200 200 GLY GLY L . n 
D 4 207 LEU 207 201 201 LEU LEU L . n 
D 4 208 SER 208 202 202 SER SER L . n 
D 4 209 SER 209 203 203 SER SER L . n 
D 4 210 PRO 210 204 204 PRO PRO L . n 
D 4 211 VAL 211 205 205 VAL VAL L . n 
D 4 212 THR 212 206 206 THR THR L . n 
D 4 213 LYS 213 207 207 LYS LYS L . n 
D 4 214 SER 214 208 208 SER SER L . n 
D 4 215 PHE 215 209 209 PHE PHE L . n 
D 4 216 ASN 216 210 210 ASN ASN L . n 
D 4 217 ARG 217 211 211 ARG ARG L . n 
D 4 218 GLY 218 212 212 GLY GLY L . n 
D 4 219 GLU 219 213 213 GLU GLU L . n 
D 4 220 CYS 220 214 ?   ?   ?   L . n 
E 5 1   GLU 1   1   1   GLU GLU G . n 
E 5 2   ILE 2   2   2   ILE ILE G . n 
E 5 3   VAL 3   3   3   VAL VAL G . n 
E 5 4   LEU 4   4   4   LEU LEU G . n 
E 5 5   THR 5   5   5   THR THR G . n 
E 5 6   GLN 6   6   6   GLN GLN G . n 
E 5 7   SER 7   7   7   SER SER G . n 
E 5 8   PRO 8   8   8   PRO PRO G . n 
E 5 9   GLY 9   9   9   GLY GLY G . n 
E 5 10  THR 10  10  10  THR THR G . n 
E 5 11  LEU 11  11  11  LEU LEU G . n 
E 5 12  SER 12  12  12  SER SER G . n 
E 5 13  LEU 13  13  13  LEU LEU G . n 
E 5 14  SER 14  14  14  SER SER G . n 
E 5 15  PRO 15  15  15  PRO PRO G . n 
E 5 16  GLY 16  16  16  GLY GLY G . n 
E 5 17  GLU 17  17  17  GLU GLU G . n 
E 5 18  ARG 18  18  18  ARG ARG G . n 
E 5 19  ALA 19  19  19  ALA ALA G . n 
E 5 20  THR 20  20  20  THR THR G . n 
E 5 21  LEU 21  21  21  LEU LEU G . n 
E 5 22  SER 22  22  22  SER SER G . n 
E 5 23  CYS 23  23  23  CYS CYS G . n 
E 5 24  ARG 24  24  24  ARG ARG G . n 
E 5 25  ALA 25  25  25  ALA ALA G . n 
E 5 26  SER 26  26  26  SER SER G . n 
E 5 27  GLN 27  27  27  GLN GLN G . n 
E 5 28  SER 28  28  28  SER SER G . n 
E 5 29  VAL 29  29  29  VAL VAL G . n 
E 5 30  SER 30  30  30  SER SER G . n 
E 5 31  SER 31  31  31  SER SER G . n 
E 5 32  TYR 32  32  32  TYR TYR G . n 
E 5 33  LEU 33  33  33  LEU LEU G . n 
E 5 34  ALA 34  34  34  ALA ALA G . n 
E 5 35  TRP 35  35  35  TRP TRP G . n 
E 5 36  TYR 36  36  36  TYR TYR G . n 
E 5 37  GLN 37  37  37  GLN GLN G . n 
E 5 38  GLN 38  38  38  GLN GLN G . n 
E 5 39  LYS 39  39  39  LYS LYS G . n 
E 5 40  PRO 40  40  40  PRO PRO G . n 
E 5 41  GLY 41  41  41  GLY GLY G . n 
E 5 42  GLN 42  42  42  GLN GLN G . n 
E 5 43  ALA 43  43  43  ALA ALA G . n 
E 5 44  PRO 44  44  44  PRO PRO G . n 
E 5 45  ARG 45  45  45  ARG ARG G . n 
E 5 46  LEU 46  46  46  LEU LEU G . n 
E 5 47  LEU 47  47  47  LEU LEU G . n 
E 5 48  ILE 48  48  48  ILE ILE G . n 
E 5 49  TYR 49  49  49  TYR TYR G . n 
E 5 50  GLY 50  50  50  GLY GLY G . n 
E 5 51  ALA 51  51  51  ALA ALA G . n 
E 5 52  SER 52  52  52  SER SER G . n 
E 5 53  SER 53  53  53  SER SER G . n 
E 5 54  ARG 54  54  54  ARG ARG G . n 
E 5 55  ALA 55  55  55  ALA ALA G . n 
E 5 56  THR 56  56  56  THR THR G . n 
E 5 57  GLY 57  57  57  GLY GLY G . n 
E 5 58  ILE 58  58  58  ILE ILE G . n 
E 5 59  PRO 59  59  59  PRO PRO G . n 
E 5 60  ASP 60  60  60  ASP ASP G . n 
E 5 61  ARG 61  61  61  ARG ARG G . n 
E 5 62  PHE 62  62  62  PHE PHE G . n 
E 5 63  SER 63  63  63  SER SER G . n 
E 5 64  GLY 64  64  64  GLY GLY G . n 
E 5 65  SER 65  65  65  SER SER G . n 
E 5 66  GLY 66  66  66  GLY GLY G . n 
E 5 67  SER 67  67  67  SER SER G . n 
E 5 68  GLY 68  68  68  GLY GLY G . n 
E 5 69  THR 69  69  69  THR THR G . n 
E 5 70  ASP 70  70  70  ASP ASP G . n 
E 5 71  PHE 71  71  71  PHE PHE G . n 
E 5 72  THR 72  72  72  THR THR G . n 
E 5 73  LEU 73  73  73  LEU LEU G . n 
E 5 74  THR 74  74  74  THR THR G . n 
E 5 75  ILE 75  75  75  ILE ILE G . n 
E 5 76  SER 76  76  76  SER SER G . n 
E 5 77  ARG 77  77  77  ARG ARG G . n 
E 5 78  LEU 78  78  78  LEU LEU G . n 
E 5 79  GLU 79  79  79  GLU GLU G . n 
E 5 80  PRO 80  80  80  PRO PRO G . n 
E 5 81  GLU 81  81  81  GLU GLU G . n 
E 5 82  ASP 82  82  82  ASP ASP G . n 
E 5 83  PHE 83  83  83  PHE PHE G . n 
E 5 84  ALA 84  84  84  ALA ALA G . n 
E 5 85  VAL 85  85  85  VAL VAL G . n 
E 5 86  TYR 86  86  86  TYR TYR G . n 
E 5 87  TYR 87  87  87  TYR TYR G . n 
E 5 88  CYS 88  88  88  CYS CYS G . n 
E 5 89  GLN 89  89  89  GLN GLN G . n 
E 5 90  GLN 90  90  90  GLN GLN G . n 
E 5 91  TYR 91  91  91  TYR TYR G . n 
E 5 92  GLY 92  92  92  GLY GLY G . n 
E 5 93  SER 93  93  93  SER SER G . n 
E 5 94  SER 94  94  94  SER SER G . n 
E 5 95  PRO 95  95  95  PRO PRO G . n 
E 5 96  ARG 96  96  96  ARG ARG G . n 
E 5 97  THR 97  97  97  THR THR G . n 
E 5 98  PHE 98  98  98  PHE PHE G . n 
E 5 99  GLY 99  99  99  GLY GLY G . n 
E 5 100 GLN 100 100 100 GLN GLN G . n 
E 5 101 GLY 101 101 101 GLY GLY G . n 
E 5 102 THR 102 102 102 THR THR G . n 
E 5 103 LYS 103 103 103 LYS LYS G . n 
E 5 104 LEU 104 104 104 LEU LEU G . n 
E 5 105 GLU 105 105 105 GLU GLU G . n 
E 5 106 ILE 106 106 106 ILE ILE G . n 
E 5 107 LYS 107 107 107 LYS LYS G . n 
E 5 108 ARG 108 108 108 ARG ARG G . n 
E 5 109 THR 109 109 109 THR THR G . n 
E 5 110 VAL 110 110 110 VAL VAL G . n 
E 5 111 ALA 111 111 111 ALA ALA G . n 
E 5 112 ALA 112 112 112 ALA ALA G . n 
E 5 113 PRO 113 113 113 PRO PRO G . n 
E 5 114 SER 114 114 114 SER SER G . n 
E 5 115 VAL 115 115 115 VAL VAL G . n 
E 5 116 PHE 116 116 116 PHE PHE G . n 
E 5 117 ILE 117 117 117 ILE ILE G . n 
E 5 118 PHE 118 118 118 PHE PHE G . n 
E 5 119 PRO 119 119 119 PRO PRO G . n 
E 5 120 PRO 120 120 120 PRO PRO G . n 
E 5 121 SER 121 121 121 SER SER G . n 
E 5 122 ASP 122 122 122 ASP ASP G . n 
E 5 123 GLU 123 123 123 GLU GLU G . n 
E 5 124 GLN 124 124 124 GLN GLN G . n 
E 5 125 LEU 125 125 125 LEU LEU G . n 
E 5 126 LYS 126 126 126 LYS LYS G . n 
E 5 127 SER 127 127 127 SER SER G . n 
E 5 128 GLY 128 128 128 GLY GLY G . n 
E 5 129 THR 129 129 129 THR THR G . n 
E 5 130 ALA 130 130 130 ALA ALA G . n 
E 5 131 SER 131 131 131 SER SER G . n 
E 5 132 VAL 132 132 132 VAL VAL G . n 
E 5 133 VAL 133 133 133 VAL VAL G . n 
E 5 134 CYS 134 134 134 CYS CYS G . n 
E 5 135 LEU 135 135 135 LEU LEU G . n 
E 5 136 LEU 136 136 136 LEU LEU G . n 
E 5 137 ASN 137 137 137 ASN ASN G . n 
E 5 138 ASN 138 138 138 ASN ASN G . n 
E 5 139 PHE 139 139 139 PHE PHE G . n 
E 5 140 TYR 140 140 140 TYR TYR G . n 
E 5 141 PRO 141 141 141 PRO PRO G . n 
E 5 142 ARG 142 142 142 ARG ARG G . n 
E 5 143 GLU 143 143 143 GLU GLU G . n 
E 5 144 ALA 144 144 144 ALA ALA G . n 
E 5 145 LYS 145 145 145 LYS LYS G . n 
E 5 146 VAL 146 146 146 VAL VAL G . n 
E 5 147 GLN 147 147 147 GLN GLN G . n 
E 5 148 TRP 148 148 148 TRP TRP G . n 
E 5 149 LYS 149 149 149 LYS LYS G . n 
E 5 150 VAL 150 150 150 VAL VAL G . n 
E 5 151 ASP 151 151 151 ASP ASP G . n 
E 5 152 ASN 152 152 152 ASN ASN G . n 
E 5 153 ALA 153 153 153 ALA ALA G . n 
E 5 154 LEU 154 154 154 LEU LEU G . n 
E 5 155 GLN 155 155 155 GLN GLN G . n 
E 5 156 SER 156 156 156 SER SER G . n 
E 5 157 GLY 157 157 157 GLY GLY G . n 
E 5 158 ASN 158 158 158 ASN ASN G . n 
E 5 159 SER 159 159 159 SER SER G . n 
E 5 160 GLN 160 160 160 GLN GLN G . n 
E 5 161 GLU 161 161 161 GLU GLU G . n 
E 5 162 SER 162 162 162 SER SER G . n 
E 5 163 VAL 163 163 163 VAL VAL G . n 
E 5 164 THR 164 164 164 THR THR G . n 
E 5 165 GLU 165 165 165 GLU GLU G . n 
E 5 166 GLN 166 166 166 GLN GLN G . n 
E 5 167 ASP 167 167 167 ASP ASP G . n 
E 5 168 SER 168 168 168 SER SER G . n 
E 5 169 LYS 169 169 169 LYS LYS G . n 
E 5 170 ASP 170 170 170 ASP ASP G . n 
E 5 171 SER 171 171 171 SER SER G . n 
E 5 172 THR 172 172 172 THR THR G . n 
E 5 173 TYR 173 173 173 TYR TYR G . n 
E 5 174 SER 174 174 174 SER SER G . n 
E 5 175 LEU 175 175 175 LEU LEU G . n 
E 5 176 SER 176 176 176 SER SER G . n 
E 5 177 SER 177 177 177 SER SER G . n 
E 5 178 THR 178 178 178 THR THR G . n 
E 5 179 LEU 179 179 179 LEU LEU G . n 
E 5 180 THR 180 180 180 THR THR G . n 
E 5 181 LEU 181 181 181 LEU LEU G . n 
E 5 182 SER 182 182 182 SER SER G . n 
E 5 183 LYS 183 183 183 LYS LYS G . n 
E 5 184 ALA 184 184 184 ALA ALA G . n 
E 5 185 ASP 185 185 185 ASP ASP G . n 
E 5 186 TYR 186 186 186 TYR TYR G . n 
E 5 187 GLU 187 187 187 GLU GLU G . n 
E 5 188 LYS 188 188 188 LYS LYS G . n 
E 5 189 HIS 189 189 189 HIS HIS G . n 
E 5 190 LYS 190 190 190 LYS LYS G . n 
E 5 191 VAL 191 191 191 VAL VAL G . n 
E 5 192 TYR 192 192 192 TYR TYR G . n 
E 5 193 ALA 193 193 193 ALA ALA G . n 
E 5 194 CYS 194 194 194 CYS CYS G . n 
E 5 195 GLU 195 195 195 GLU GLU G . n 
E 5 196 VAL 196 196 196 VAL VAL G . n 
E 5 197 THR 197 197 197 THR THR G . n 
E 5 198 HIS 198 198 198 HIS HIS G . n 
E 5 199 GLN 199 199 199 GLN GLN G . n 
E 5 200 GLY 200 200 200 GLY GLY G . n 
E 5 201 LEU 201 201 201 LEU LEU G . n 
E 5 202 SER 202 202 202 SER SER G . n 
E 5 203 SER 203 203 203 SER SER G . n 
E 5 204 PRO 204 204 204 PRO PRO G . n 
E 5 205 VAL 205 205 205 VAL VAL G . n 
E 5 206 THR 206 206 206 THR THR G . n 
E 5 207 LYS 207 207 207 LYS LYS G . n 
E 5 208 SER 208 208 208 SER SER G . n 
E 5 209 PHE 209 209 209 PHE PHE G . n 
E 5 210 ASN 210 210 210 ASN ASN G . n 
E 5 211 ARG 211 211 211 ARG ARG G . n 
E 5 212 GLY 212 212 ?   ?   ?   G . n 
E 5 213 GLU 213 213 ?   ?   ?   G . n 
E 5 214 CYS 214 214 ?   ?   ?   G . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
F 6 NAG 1 B NAG 1 B NAG 1 n 
F 6 NAG 2 B NAG 2 B NAG 2 n 
F 6 BMA 3 B BMA 3 B BMA 3 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 7 HOH 1   601 531  HOH HOH A . 
G 7 HOH 2   602 119  HOH HOH A . 
G 7 HOH 3   603 198  HOH HOH A . 
G 7 HOH 4   604 20   HOH HOH A . 
G 7 HOH 5   605 714  HOH HOH A . 
G 7 HOH 6   606 218  HOH HOH A . 
G 7 HOH 7   607 4    HOH HOH A . 
G 7 HOH 8   608 9    HOH HOH A . 
G 7 HOH 9   609 474  HOH HOH A . 
G 7 HOH 10  610 548  HOH HOH A . 
G 7 HOH 11  611 33   HOH HOH A . 
G 7 HOH 12  612 3    HOH HOH A . 
G 7 HOH 13  613 146  HOH HOH A . 
G 7 HOH 14  614 316  HOH HOH A . 
G 7 HOH 15  615 245  HOH HOH A . 
G 7 HOH 16  616 1582 HOH HOH A . 
G 7 HOH 17  617 16   HOH HOH A . 
G 7 HOH 18  618 57   HOH HOH A . 
G 7 HOH 19  619 865  HOH HOH A . 
G 7 HOH 20  620 564  HOH HOH A . 
G 7 HOH 21  621 49   HOH HOH A . 
G 7 HOH 22  622 313  HOH HOH A . 
G 7 HOH 23  623 282  HOH HOH A . 
G 7 HOH 24  624 26   HOH HOH A . 
G 7 HOH 25  625 460  HOH HOH A . 
G 7 HOH 26  626 583  HOH HOH A . 
G 7 HOH 27  627 210  HOH HOH A . 
G 7 HOH 28  628 244  HOH HOH A . 
G 7 HOH 29  629 81   HOH HOH A . 
G 7 HOH 30  630 565  HOH HOH A . 
G 7 HOH 31  631 563  HOH HOH A . 
G 7 HOH 32  632 43   HOH HOH A . 
G 7 HOH 33  633 98   HOH HOH A . 
G 7 HOH 34  634 339  HOH HOH A . 
G 7 HOH 35  635 69   HOH HOH A . 
G 7 HOH 36  636 772  HOH HOH A . 
G 7 HOH 37  637 631  HOH HOH A . 
G 7 HOH 38  638 1160 HOH HOH A . 
G 7 HOH 39  639 293  HOH HOH A . 
G 7 HOH 40  640 263  HOH HOH A . 
G 7 HOH 41  641 632  HOH HOH A . 
G 7 HOH 42  642 161  HOH HOH A . 
G 7 HOH 43  643 83   HOH HOH A . 
G 7 HOH 44  644 855  HOH HOH A . 
G 7 HOH 45  645 945  HOH HOH A . 
G 7 HOH 46  646 1570 HOH HOH A . 
G 7 HOH 47  647 444  HOH HOH A . 
G 7 HOH 48  648 1007 HOH HOH A . 
G 7 HOH 49  649 1571 HOH HOH A . 
G 7 HOH 50  650 354  HOH HOH A . 
G 7 HOH 51  651 956  HOH HOH A . 
G 7 HOH 52  652 629  HOH HOH A . 
G 7 HOH 53  653 63   HOH HOH A . 
G 7 HOH 54  654 54   HOH HOH A . 
G 7 HOH 55  655 196  HOH HOH A . 
G 7 HOH 56  656 235  HOH HOH A . 
G 7 HOH 57  657 1562 HOH HOH A . 
G 7 HOH 58  658 647  HOH HOH A . 
G 7 HOH 59  659 320  HOH HOH A . 
G 7 HOH 60  660 1580 HOH HOH A . 
G 7 HOH 61  661 315  HOH HOH A . 
G 7 HOH 62  662 570  HOH HOH A . 
G 7 HOH 63  663 506  HOH HOH A . 
G 7 HOH 64  664 1567 HOH HOH A . 
G 7 HOH 65  665 974  HOH HOH A . 
G 7 HOH 66  666 1566 HOH HOH A . 
G 7 HOH 67  667 823  HOH HOH A . 
G 7 HOH 68  668 840  HOH HOH A . 
G 7 HOH 69  669 1109 HOH HOH A . 
G 7 HOH 70  670 1466 HOH HOH A . 
G 7 HOH 71  671 1218 HOH HOH A . 
G 7 HOH 72  672 1462 HOH HOH A . 
G 7 HOH 73  673 1425 HOH HOH A . 
G 7 HOH 74  674 1093 HOH HOH A . 
G 7 HOH 75  675 611  HOH HOH A . 
G 7 HOH 76  676 1121 HOH HOH A . 
G 7 HOH 77  677 606  HOH HOH A . 
G 7 HOH 78  678 1579 HOH HOH A . 
G 7 HOH 79  679 616  HOH HOH A . 
G 7 HOH 80  680 751  HOH HOH A . 
G 7 HOH 81  681 701  HOH HOH A . 
G 7 HOH 82  682 1557 HOH HOH A . 
G 7 HOH 83  683 1224 HOH HOH A . 
H 7 HOH 1   301 507  HOH HOH H . 
H 7 HOH 2   302 92   HOH HOH H . 
H 7 HOH 3   303 173  HOH HOH H . 
H 7 HOH 4   304 228  HOH HOH H . 
H 7 HOH 5   305 12   HOH HOH H . 
H 7 HOH 6   306 640  HOH HOH H . 
H 7 HOH 7   307 723  HOH HOH H . 
H 7 HOH 8   308 1437 HOH HOH H . 
H 7 HOH 9   309 290  HOH HOH H . 
H 7 HOH 10  310 117  HOH HOH H . 
H 7 HOH 11  311 10   HOH HOH H . 
H 7 HOH 12  312 11   HOH HOH H . 
H 7 HOH 13  313 53   HOH HOH H . 
H 7 HOH 14  314 7    HOH HOH H . 
H 7 HOH 15  315 107  HOH HOH H . 
H 7 HOH 16  316 179  HOH HOH H . 
H 7 HOH 17  317 547  HOH HOH H . 
H 7 HOH 18  318 1393 HOH HOH H . 
H 7 HOH 19  319 892  HOH HOH H . 
H 7 HOH 20  320 815  HOH HOH H . 
H 7 HOH 21  321 65   HOH HOH H . 
H 7 HOH 22  322 556  HOH HOH H . 
H 7 HOH 23  323 36   HOH HOH H . 
H 7 HOH 24  324 1382 HOH HOH H . 
H 7 HOH 25  325 335  HOH HOH H . 
H 7 HOH 26  326 29   HOH HOH H . 
H 7 HOH 27  327 251  HOH HOH H . 
H 7 HOH 28  328 1006 HOH HOH H . 
H 7 HOH 29  329 533  HOH HOH H . 
H 7 HOH 30  330 181  HOH HOH H . 
H 7 HOH 31  331 553  HOH HOH H . 
H 7 HOH 32  332 37   HOH HOH H . 
H 7 HOH 33  333 254  HOH HOH H . 
H 7 HOH 34  334 1285 HOH HOH H . 
H 7 HOH 35  335 18   HOH HOH H . 
H 7 HOH 36  336 924  HOH HOH H . 
H 7 HOH 37  337 331  HOH HOH H . 
H 7 HOH 38  338 390  HOH HOH H . 
H 7 HOH 39  339 785  HOH HOH H . 
H 7 HOH 40  340 1058 HOH HOH H . 
H 7 HOH 41  341 41   HOH HOH H . 
H 7 HOH 42  342 86   HOH HOH H . 
H 7 HOH 43  343 265  HOH HOH H . 
H 7 HOH 44  344 806  HOH HOH H . 
H 7 HOH 45  345 62   HOH HOH H . 
H 7 HOH 46  346 151  HOH HOH H . 
H 7 HOH 47  347 166  HOH HOH H . 
H 7 HOH 48  348 51   HOH HOH H . 
H 7 HOH 49  349 537  HOH HOH H . 
H 7 HOH 50  350 127  HOH HOH H . 
H 7 HOH 51  351 262  HOH HOH H . 
H 7 HOH 52  352 445  HOH HOH H . 
H 7 HOH 53  353 30   HOH HOH H . 
H 7 HOH 54  354 435  HOH HOH H . 
H 7 HOH 55  355 56   HOH HOH H . 
H 7 HOH 56  356 682  HOH HOH H . 
H 7 HOH 57  357 183  HOH HOH H . 
H 7 HOH 58  358 779  HOH HOH H . 
H 7 HOH 59  359 121  HOH HOH H . 
H 7 HOH 60  360 1119 HOH HOH H . 
H 7 HOH 61  361 1242 HOH HOH H . 
H 7 HOH 62  362 295  HOH HOH H . 
H 7 HOH 63  363 200  HOH HOH H . 
H 7 HOH 64  364 1113 HOH HOH H . 
H 7 HOH 65  365 1583 HOH HOH H . 
H 7 HOH 66  366 239  HOH HOH H . 
H 7 HOH 67  367 727  HOH HOH H . 
H 7 HOH 68  368 193  HOH HOH H . 
H 7 HOH 69  369 21   HOH HOH H . 
H 7 HOH 70  370 980  HOH HOH H . 
H 7 HOH 71  371 695  HOH HOH H . 
H 7 HOH 72  372 1363 HOH HOH H . 
H 7 HOH 73  373 137  HOH HOH H . 
H 7 HOH 74  374 776  HOH HOH H . 
H 7 HOH 75  375 1277 HOH HOH H . 
H 7 HOH 76  376 717  HOH HOH H . 
H 7 HOH 77  377 1342 HOH HOH H . 
H 7 HOH 78  378 174  HOH HOH H . 
H 7 HOH 79  379 771  HOH HOH H . 
H 7 HOH 80  380 1558 HOH HOH H . 
H 7 HOH 81  381 122  HOH HOH H . 
H 7 HOH 82  382 604  HOH HOH H . 
H 7 HOH 83  383 593  HOH HOH H . 
H 7 HOH 84  384 665  HOH HOH H . 
H 7 HOH 85  385 1062 HOH HOH H . 
H 7 HOH 86  386 786  HOH HOH H . 
H 7 HOH 87  387 158  HOH HOH H . 
H 7 HOH 88  388 763  HOH HOH H . 
H 7 HOH 89  389 630  HOH HOH H . 
H 7 HOH 90  390 1561 HOH HOH H . 
H 7 HOH 91  391 662  HOH HOH H . 
H 7 HOH 92  392 424  HOH HOH H . 
H 7 HOH 93  393 893  HOH HOH H . 
I 7 HOH 1   301 279  HOH HOH F . 
I 7 HOH 2   302 655  HOH HOH F . 
I 7 HOH 3   303 378  HOH HOH F . 
I 7 HOH 4   304 1486 HOH HOH F . 
I 7 HOH 5   305 68   HOH HOH F . 
I 7 HOH 6   306 195  HOH HOH F . 
I 7 HOH 7   307 1461 HOH HOH F . 
I 7 HOH 8   308 38   HOH HOH F . 
I 7 HOH 9   309 1237 HOH HOH F . 
I 7 HOH 10  310 59   HOH HOH F . 
I 7 HOH 11  311 668  HOH HOH F . 
I 7 HOH 12  312 72   HOH HOH F . 
I 7 HOH 13  313 486  HOH HOH F . 
I 7 HOH 14  314 204  HOH HOH F . 
I 7 HOH 15  315 493  HOH HOH F . 
I 7 HOH 16  316 79   HOH HOH F . 
I 7 HOH 17  317 28   HOH HOH F . 
I 7 HOH 18  318 1083 HOH HOH F . 
I 7 HOH 19  319 109  HOH HOH F . 
I 7 HOH 20  320 351  HOH HOH F . 
I 7 HOH 21  321 301  HOH HOH F . 
I 7 HOH 22  322 602  HOH HOH F . 
I 7 HOH 23  323 739  HOH HOH F . 
I 7 HOH 24  324 163  HOH HOH F . 
I 7 HOH 25  325 180  HOH HOH F . 
I 7 HOH 26  326 1270 HOH HOH F . 
I 7 HOH 27  327 1288 HOH HOH F . 
I 7 HOH 28  328 938  HOH HOH F . 
I 7 HOH 29  329 359  HOH HOH F . 
I 7 HOH 30  330 110  HOH HOH F . 
I 7 HOH 31  331 47   HOH HOH F . 
I 7 HOH 32  332 387  HOH HOH F . 
I 7 HOH 33  333 100  HOH HOH F . 
I 7 HOH 34  334 1000 HOH HOH F . 
I 7 HOH 35  335 145  HOH HOH F . 
I 7 HOH 36  336 93   HOH HOH F . 
I 7 HOH 37  337 1556 HOH HOH F . 
I 7 HOH 38  338 834  HOH HOH F . 
I 7 HOH 39  339 278  HOH HOH F . 
I 7 HOH 40  340 275  HOH HOH F . 
I 7 HOH 41  341 1173 HOH HOH F . 
I 7 HOH 42  342 289  HOH HOH F . 
I 7 HOH 43  343 89   HOH HOH F . 
I 7 HOH 44  344 857  HOH HOH F . 
I 7 HOH 45  345 1229 HOH HOH F . 
I 7 HOH 46  346 915  HOH HOH F . 
I 7 HOH 47  347 601  HOH HOH F . 
I 7 HOH 48  348 1269 HOH HOH F . 
I 7 HOH 49  349 1103 HOH HOH F . 
I 7 HOH 50  350 555  HOH HOH F . 
I 7 HOH 51  351 543  HOH HOH F . 
I 7 HOH 52  352 46   HOH HOH F . 
I 7 HOH 53  353 189  HOH HOH F . 
I 7 HOH 54  354 1014 HOH HOH F . 
I 7 HOH 55  355 1019 HOH HOH F . 
I 7 HOH 56  356 177  HOH HOH F . 
I 7 HOH 57  357 5    HOH HOH F . 
I 7 HOH 58  358 220  HOH HOH F . 
I 7 HOH 59  359 989  HOH HOH F . 
I 7 HOH 60  360 1559 HOH HOH F . 
I 7 HOH 61  361 1564 HOH HOH F . 
I 7 HOH 62  362 539  HOH HOH F . 
I 7 HOH 63  363 638  HOH HOH F . 
I 7 HOH 64  364 1581 HOH HOH F . 
I 7 HOH 65  365 811  HOH HOH F . 
I 7 HOH 66  366 918  HOH HOH F . 
I 7 HOH 67  367 820  HOH HOH F . 
I 7 HOH 68  368 1576 HOH HOH F . 
I 7 HOH 69  369 1010 HOH HOH F . 
I 7 HOH 70  370 1236 HOH HOH F . 
I 7 HOH 71  371 1210 HOH HOH F . 
I 7 HOH 72  372 755  HOH HOH F . 
J 7 HOH 1   301 169  HOH HOH L . 
J 7 HOH 2   302 1545 HOH HOH L . 
J 7 HOH 3   303 85   HOH HOH L . 
J 7 HOH 4   304 150  HOH HOH L . 
J 7 HOH 5   305 39   HOH HOH L . 
J 7 HOH 6   306 223  HOH HOH L . 
J 7 HOH 7   307 1569 HOH HOH L . 
J 7 HOH 8   308 491  HOH HOH L . 
J 7 HOH 9   309 226  HOH HOH L . 
J 7 HOH 10  310 1573 HOH HOH L . 
J 7 HOH 11  311 40   HOH HOH L . 
J 7 HOH 12  312 268  HOH HOH L . 
J 7 HOH 13  313 269  HOH HOH L . 
J 7 HOH 14  314 866  HOH HOH L . 
J 7 HOH 15  315 1200 HOH HOH L . 
J 7 HOH 16  316 106  HOH HOH L . 
J 7 HOH 17  317 71   HOH HOH L . 
J 7 HOH 18  318 101  HOH HOH L . 
J 7 HOH 19  319 91   HOH HOH L . 
J 7 HOH 20  320 175  HOH HOH L . 
J 7 HOH 21  321 1036 HOH HOH L . 
J 7 HOH 22  322 464  HOH HOH L . 
J 7 HOH 23  323 362  HOH HOH L . 
J 7 HOH 24  324 688  HOH HOH L . 
J 7 HOH 25  325 219  HOH HOH L . 
J 7 HOH 26  326 308  HOH HOH L . 
J 7 HOH 27  327 197  HOH HOH L . 
J 7 HOH 28  328 272  HOH HOH L . 
J 7 HOH 29  329 35   HOH HOH L . 
J 7 HOH 30  330 22   HOH HOH L . 
J 7 HOH 31  331 203  HOH HOH L . 
J 7 HOH 32  332 400  HOH HOH L . 
J 7 HOH 33  333 807  HOH HOH L . 
J 7 HOH 34  334 113  HOH HOH L . 
J 7 HOH 35  335 206  HOH HOH L . 
J 7 HOH 36  336 136  HOH HOH L . 
J 7 HOH 37  337 699  HOH HOH L . 
J 7 HOH 38  338 1149 HOH HOH L . 
J 7 HOH 39  339 139  HOH HOH L . 
J 7 HOH 40  340 32   HOH HOH L . 
J 7 HOH 41  341 240  HOH HOH L . 
J 7 HOH 42  342 154  HOH HOH L . 
J 7 HOH 43  343 304  HOH HOH L . 
J 7 HOH 44  344 789  HOH HOH L . 
J 7 HOH 45  345 497  HOH HOH L . 
J 7 HOH 46  346 520  HOH HOH L . 
J 7 HOH 47  347 78   HOH HOH L . 
J 7 HOH 48  348 729  HOH HOH L . 
J 7 HOH 49  349 160  HOH HOH L . 
J 7 HOH 50  350 221  HOH HOH L . 
J 7 HOH 51  351 1281 HOH HOH L . 
J 7 HOH 52  352 155  HOH HOH L . 
J 7 HOH 53  353 58   HOH HOH L . 
J 7 HOH 54  354 691  HOH HOH L . 
J 7 HOH 55  355 432  HOH HOH L . 
J 7 HOH 56  356 167  HOH HOH L . 
J 7 HOH 57  357 440  HOH HOH L . 
J 7 HOH 58  358 1496 HOH HOH L . 
J 7 HOH 59  359 456  HOH HOH L . 
J 7 HOH 60  360 1238 HOH HOH L . 
J 7 HOH 61  361 618  HOH HOH L . 
J 7 HOH 62  362 749  HOH HOH L . 
J 7 HOH 63  363 73   HOH HOH L . 
J 7 HOH 64  364 1535 HOH HOH L . 
J 7 HOH 65  365 284  HOH HOH L . 
J 7 HOH 66  366 1106 HOH HOH L . 
J 7 HOH 67  367 44   HOH HOH L . 
J 7 HOH 68  368 437  HOH HOH L . 
J 7 HOH 69  369 720  HOH HOH L . 
J 7 HOH 70  370 1124 HOH HOH L . 
J 7 HOH 71  371 42   HOH HOH L . 
J 7 HOH 72  372 336  HOH HOH L . 
J 7 HOH 73  373 514  HOH HOH L . 
J 7 HOH 74  374 501  HOH HOH L . 
J 7 HOH 75  375 236  HOH HOH L . 
J 7 HOH 76  376 297  HOH HOH L . 
J 7 HOH 77  377 1085 HOH HOH L . 
J 7 HOH 78  378 55   HOH HOH L . 
J 7 HOH 79  379 1572 HOH HOH L . 
J 7 HOH 80  380 925  HOH HOH L . 
J 7 HOH 81  381 466  HOH HOH L . 
J 7 HOH 82  382 6    HOH HOH L . 
J 7 HOH 83  383 384  HOH HOH L . 
J 7 HOH 84  384 1112 HOH HOH L . 
J 7 HOH 85  385 1568 HOH HOH L . 
J 7 HOH 86  386 1492 HOH HOH L . 
J 7 HOH 87  387 408  HOH HOH L . 
J 7 HOH 88  388 1565 HOH HOH L . 
J 7 HOH 89  389 470  HOH HOH L . 
J 7 HOH 90  390 1538 HOH HOH L . 
J 7 HOH 91  391 1283 HOH HOH L . 
J 7 HOH 92  392 1563 HOH HOH L . 
J 7 HOH 93  393 596  HOH HOH L . 
J 7 HOH 94  394 1560 HOH HOH L . 
J 7 HOH 95  395 661  HOH HOH L . 
J 7 HOH 96  396 1574 HOH HOH L . 
J 7 HOH 97  397 761  HOH HOH L . 
J 7 HOH 98  398 1220 HOH HOH L . 
J 7 HOH 99  399 1479 HOH HOH L . 
J 7 HOH 100 400 1490 HOH HOH L . 
J 7 HOH 101 401 1493 HOH HOH L . 
K 7 HOH 1   301 50   HOH HOH G . 
K 7 HOH 2   302 1272 HOH HOH G . 
K 7 HOH 3   303 527  HOH HOH G . 
K 7 HOH 4   304 70   HOH HOH G . 
K 7 HOH 5   305 450  HOH HOH G . 
K 7 HOH 6   306 217  HOH HOH G . 
K 7 HOH 7   307 1442 HOH HOH G . 
K 7 HOH 8   308 825  HOH HOH G . 
K 7 HOH 9   309 1278 HOH HOH G . 
K 7 HOH 10  310 123  HOH HOH G . 
K 7 HOH 11  311 112  HOH HOH G . 
K 7 HOH 12  312 164  HOH HOH G . 
K 7 HOH 13  313 947  HOH HOH G . 
K 7 HOH 14  314 685  HOH HOH G . 
K 7 HOH 15  315 1120 HOH HOH G . 
K 7 HOH 16  316 1141 HOH HOH G . 
K 7 HOH 17  317 698  HOH HOH G . 
K 7 HOH 18  318 705  HOH HOH G . 
K 7 HOH 19  319 836  HOH HOH G . 
K 7 HOH 20  320 48   HOH HOH G . 
K 7 HOH 21  321 287  HOH HOH G . 
K 7 HOH 22  322 1214 HOH HOH G . 
K 7 HOH 23  323 1359 HOH HOH G . 
K 7 HOH 24  324 1171 HOH HOH G . 
K 7 HOH 25  325 94   HOH HOH G . 
K 7 HOH 26  326 1003 HOH HOH G . 
K 7 HOH 27  327 260  HOH HOH G . 
K 7 HOH 28  328 1391 HOH HOH G . 
K 7 HOH 29  329 903  HOH HOH G . 
K 7 HOH 30  330 148  HOH HOH G . 
K 7 HOH 31  331 343  HOH HOH G . 
K 7 HOH 32  332 23   HOH HOH G . 
K 7 HOH 33  333 1533 HOH HOH G . 
K 7 HOH 34  334 178  HOH HOH G . 
K 7 HOH 35  335 349  HOH HOH G . 
K 7 HOH 36  336 319  HOH HOH G . 
K 7 HOH 37  337 1577 HOH HOH G . 
K 7 HOH 38  338 99   HOH HOH G . 
K 7 HOH 39  339 495  HOH HOH G . 
K 7 HOH 40  340 1094 HOH HOH G . 
K 7 HOH 41  341 443  HOH HOH G . 
K 7 HOH 42  342 1175 HOH HOH G . 
K 7 HOH 43  343 147  HOH HOH G . 
K 7 HOH 44  344 658  HOH HOH G . 
K 7 HOH 45  345 1289 HOH HOH G . 
K 7 HOH 46  346 656  HOH HOH G . 
K 7 HOH 47  347 368  HOH HOH G . 
K 7 HOH 48  348 526  HOH HOH G . 
K 7 HOH 49  349 1110 HOH HOH G . 
K 7 HOH 50  350 1353 HOH HOH G . 
K 7 HOH 51  351 1514 HOH HOH G . 
K 7 HOH 52  352 277  HOH HOH G . 
K 7 HOH 53  353 1575 HOH HOH G . 
K 7 HOH 54  354 1578 HOH HOH G . 
K 7 HOH 55  355 985  HOH HOH G . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.21rc1_5127: ???)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                     2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                     3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .                     4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CPU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     110.232 
_cell.length_a_esd                 ? 
_cell.length_b                     110.232 
_cell.length_b_esd                 ? 
_cell.length_c                     230.348 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CPU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                92 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 41 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CPU 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.97 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58.65 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Tris, pH 8, 15% v/v ethylene glycol, 1 M lithium chloride, 10% w/v PEG6000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-04-18 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97946 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97946 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9CPU 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.60 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     44734 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                26.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.871 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.101 
_reflns.pdbx_Rpim_I_all                                0.020 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       1188872 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.970 
_reflns.pdbx_CC_star                                   0.992 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.099 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
2.60 2.64  ? ? ? ? ? ? 2188 ? ? ? ? ? ? ? ? ? ? ? 27.8 0.819 ? ? 1.623 0.303 ? 1  1 0.853 0.960 ? 100.0 ? 1.594 ? ? ? ? ? ? ? ? ? 
2.64 2.69  ? ? ? ? ? ? 2210 ? ? ? ? ? ? ? ? ? ? ? 27.4 0.960 ? ? 1.342 0.253 ? 2  1 0.884 0.969 ? 100.0 ? 1.318 ? ? ? ? ? ? ? ? ? 
2.69 2.74  ? ? ? ? ? ? 2177 ? ? ? ? ? ? ? ? ? ? ? 28.4 0.834 ? ? 1.097 0.203 ? 3  1 0.913 0.977 ? 100.0 ? 1.077 ? ? ? ? ? ? ? ? ? 
2.74 2.80  ? ? ? ? ? ? 2177 ? ? ? ? ? ? ? ? ? ? ? 27.7 0.834 ? ? 0.888 0.167 ? 4  1 0.934 0.983 ? 100.0 ? 0.872 ? ? ? ? ? ? ? ? ? 
2.80 2.86  ? ? ? ? ? ? 2218 ? ? ? ? ? ? ? ? ? ? ? 27.6 0.847 ? ? 0.746 0.140 ? 5  1 0.952 0.988 ? 100.0 ? 0.733 ? ? ? ? ? ? ? ? ? 
2.86 2.93  ? ? ? ? ? ? 2201 ? ? ? ? ? ? ? ? ? ? ? 27.5 0.863 ? ? 0.601 0.113 ? 6  1 0.964 0.991 ? 100.0 ? 0.590 ? ? ? ? ? ? ? ? ? 
2.93 3.00  ? ? ? ? ? ? 2206 ? ? ? ? ? ? ? ? ? ? ? 27.2 0.881 ? ? 0.464 0.088 ? 7  1 0.974 0.993 ? 100.0 ? 0.456 ? ? ? ? ? ? ? ? ? 
3.00 3.08  ? ? ? ? ? ? 2221 ? ? ? ? ? ? ? ? ? ? ? 27.1 0.882 ? ? 0.380 0.072 ? 8  1 0.980 0.995 ? 100.0 ? 0.373 ? ? ? ? ? ? ? ? ? 
3.08 3.17  ? ? ? ? ? ? 2205 ? ? ? ? ? ? ? ? ? ? ? 26.8 0.907 ? ? 0.287 0.055 ? 9  1 0.983 0.996 ? 100.0 ? 0.281 ? ? ? ? ? ? ? ? ? 
3.17 3.28  ? ? ? ? ? ? 2196 ? ? ? ? ? ? ? ? ? ? ? 26.4 0.914 ? ? 0.223 0.043 ? 10 1 0.986 0.996 ? 100.0 ? 0.219 ? ? ? ? ? ? ? ? ? 
3.28 3.39  ? ? ? ? ? ? 2229 ? ? ? ? ? ? ? ? ? ? ? 25.7 0.934 ? ? 0.177 0.034 ? 11 1 0.988 0.997 ? 100.0 ? 0.173 ? ? ? ? ? ? ? ? ? 
3.39 3.53  ? ? ? ? ? ? 2218 ? ? ? ? ? ? ? ? ? ? ? 24.7 1.073 ? ? 0.148 0.030 ? 12 1 0.990 0.998 ? 100.0 ? 0.145 ? ? ? ? ? ? ? ? ? 
3.53 3.69  ? ? ? ? ? ? 2214 ? ? ? ? ? ? ? ? ? ? ? 21.8 1.006 ? ? 0.124 0.027 ? 13 1 0.983 0.996 ? 99.1  ? 0.121 ? ? ? ? ? ? ? ? ? 
3.69 3.88  ? ? ? ? ? ? 2231 ? ? ? ? ? ? ? ? ? ? ? 27.3 0.931 ? ? 0.106 0.020 ? 14 1 0.994 0.998 ? 99.9  ? 0.104 ? ? ? ? ? ? ? ? ? 
3.88 4.13  ? ? ? ? ? ? 2257 ? ? ? ? ? ? ? ? ? ? ? 28.1 0.925 ? ? 0.093 0.017 ? 15 1 0.997 0.999 ? 100.0 ? 0.091 ? ? ? ? ? ? ? ? ? 
4.13 4.45  ? ? ? ? ? ? 2245 ? ? ? ? ? ? ? ? ? ? ? 27.9 0.838 ? ? 0.081 0.015 ? 16 1 0.998 0.999 ? 100.0 ? 0.079 ? ? ? ? ? ? ? ? ? 
4.45 4.89  ? ? ? ? ? ? 2259 ? ? ? ? ? ? ? ? ? ? ? 27.2 0.803 ? ? 0.075 0.014 ? 17 1 0.998 1.000 ? 100.0 ? 0.074 ? ? ? ? ? ? ? ? ? 
4.89 5.60  ? ? ? ? ? ? 2295 ? ? ? ? ? ? ? ? ? ? ? 26.6 0.764 ? ? 0.073 0.014 ? 18 1 0.998 0.999 ? 100.0 ? 0.071 ? ? ? ? ? ? ? ? ? 
5.60 7.05  ? ? ? ? ? ? 2301 ? ? ? ? ? ? ? ? ? ? ? 23.8 0.718 ? ? 0.069 0.014 ? 19 1 0.996 0.999 ? 99.1  ? 0.067 ? ? ? ? ? ? ? ? ? 
7.05 50.00 ? ? ? ? ? ? 2486 ? ? ? ? ? ? ? ? ? ? ? 24.9 0.731 ? ? 0.065 0.013 ? 20 1 0.990 0.997 ? 99.4  ? 0.064 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CPU 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.60 
_refine.ls_d_res_low                             49.30 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     44210 
_refine.ls_number_reflns_R_free                  2000 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.82 
_refine.ls_percent_reflns_R_free                 4.52 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2076 
_refine.ls_R_factor_R_free                       0.2389 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2061 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 23.78 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.34 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        8078 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         39 
_refine_hist.number_atoms_solvent             404 
_refine_hist.number_atoms_total               8521 
_refine_hist.d_res_high                       2.60 
_refine_hist.d_res_low                        49.30 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.002  ? ?    ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.478  ? ?    ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 13.818 ? 2958 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.042  ? 1262 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.004  ? 1445 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.60 2.66  . . 125 2628 88.00  . . . . 0.2567 . . . . . . . . . . . 0.3208 
'X-RAY DIFFRACTION' 2.66 2.73  . . 138 2915 98.00  . . . . 0.2701 . . . . . . . . . . . 0.3348 
'X-RAY DIFFRACTION' 2.73 2.81  . . 141 3003 100.00 . . . . 0.2556 . . . . . . . . . . . 0.3026 
'X-RAY DIFFRACTION' 2.81 2.90  . . 144 3018 100.00 . . . . 0.2590 . . . . . . . . . . . 0.3169 
'X-RAY DIFFRACTION' 2.90 3.01  . . 142 2999 100.00 . . . . 0.2487 . . . . . . . . . . . 0.2768 
'X-RAY DIFFRACTION' 3.01 3.13  . . 142 3003 100.00 . . . . 0.2395 . . . . . . . . . . . 0.3257 
'X-RAY DIFFRACTION' 3.13 3.27  . . 142 2997 100.00 . . . . 0.2343 . . . . . . . . . . . 0.2513 
'X-RAY DIFFRACTION' 3.27 3.44  . . 144 3042 100.00 . . . . 0.2293 . . . . . . . . . . . 0.2645 
'X-RAY DIFFRACTION' 3.44 3.66  . . 144 3019 99.00  . . . . 0.2009 . . . . . . . . . . . 0.2148 
'X-RAY DIFFRACTION' 3.66 3.94  . . 144 3037 100.00 . . . . 0.1958 . . . . . . . . . . . 0.2217 
'X-RAY DIFFRACTION' 3.94 4.34  . . 144 3054 100.00 . . . . 0.1757 . . . . . . . . . . . 0.2057 
'X-RAY DIFFRACTION' 4.34 4.96  . . 147 3093 100.00 . . . . 0.1601 . . . . . . . . . . . 0.1770 
'X-RAY DIFFRACTION' 4.96 6.25  . . 148 3127 100.00 . . . . 0.1860 . . . . . . . . . . . 0.2068 
'X-RAY DIFFRACTION' 6.25 49.30 . . 155 3275 99.00  . . . . 0.1859 . . . . . . . . . . . 0.2237 
# 
_struct.entry_id                     9CPU 
_struct.title                        
'Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0304 and CC12.3' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CPU 
_struct_keywords.text            'COVID-19, SARS-CoV-2, Receptor binding domain, Antibody, VIRAL PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
G N N 7 ? 
H N N 7 ? 
I N N 7 ? 
J N N 7 ? 
K N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP SPIKE_SARS2 P0DTC2 ? 1 
;TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP
GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL
QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKS
;
333 
2 PDB 9CPU        9CPU   ? 2 ? 1   
3 PDB 9CPU        9CPU   ? 3 ? 1   
4 PDB 9CPU        9CPU   ? 4 ? 1   
5 PDB 9CPU        9CPU   ? 5 ? 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CPU A 1 ? 198 ? P0DTC2 333 ? 530 ? 333 530 
2 2 9CPU H 1 ? 222 ? 9CPU   1   ? 216 ? 1   216 
3 3 9CPU F 1 ? 220 ? 9CPU   1   ? 216 ? 1   216 
4 4 9CPU L 1 ? 220 ? 9CPU   1   ? 214 ? 1   214 
5 5 9CPU G 1 ? 214 ? 9CPU   1   ? 214 ? 1   214 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CPU GLY A 199 ? UNP P0DTC2 ? ? 'expression tag' 531 1 
1 9CPU HIS A 200 ? UNP P0DTC2 ? ? 'expression tag' 532 2 
1 9CPU HIS A 201 ? UNP P0DTC2 ? ? 'expression tag' 533 3 
1 9CPU HIS A 202 ? UNP P0DTC2 ? ? 'expression tag' 534 4 
1 9CPU HIS A 203 ? UNP P0DTC2 ? ? 'expression tag' 535 5 
1 9CPU HIS A 204 ? UNP P0DTC2 ? ? 'expression tag' 536 6 
1 9CPU HIS A 205 ? UNP P0DTC2 ? ? 'expression tag' 537 7 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 11000 ? 
1 MORE         -50   ? 
1 'SSA (A^2)'  45800 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 5   ? ASN A 11  ? PRO A 337 ASN A 343 1 ? 7 
HELX_P HELX_P2  AA2 SER A 17  ? TRP A 21  ? SER A 349 TRP A 353 5 ? 5 
HELX_P HELX_P3  AA3 TYR A 33  ? ASN A 38  ? TYR A 365 ASN A 370 1 ? 6 
HELX_P HELX_P4  AA4 SER A 51  ? LEU A 55  ? SER A 383 LEU A 387 5 ? 5 
HELX_P HELX_P5  AA5 GLU A 74  ? ILE A 78  ? GLU A 406 ILE A 410 5 ? 5 
HELX_P HELX_P6  AA6 GLY A 84  ? ASN A 90  ? GLY A 416 ASN A 422 1 ? 7 
HELX_P HELX_P7  AA7 SER A 106 ? SER A 111 ? SER A 438 SER A 443 1 ? 6 
HELX_P HELX_P8  AA8 GLY A 170 ? TYR A 173 ? GLY A 502 TYR A 505 5 ? 4 
HELX_P HELX_P9  AA9 SER B 28  ? ILE B 30  ? SER H 28  ILE H 30  5 ? 3 
HELX_P HELX_P10 AB1 LYS B 87  ? THR B 91  ? LYS H 83  THR H 87  5 ? 5 
HELX_P HELX_P11 AB2 SER B 193 ? LEU B 195 ? SER H 187 LEU H 189 5 ? 3 
HELX_P HELX_P12 AB3 LYS B 207 ? ASN B 210 ? LYS H 201 ASN H 204 5 ? 4 
HELX_P HELX_P13 AB4 THR C 28  ? ASN C 32  ? THR F 28  ASN F 32  5 ? 5 
HELX_P HELX_P14 AB5 ARG C 86  ? THR C 90  ? ARG F 83  THR F 87  5 ? 5 
HELX_P HELX_P15 AB6 GLN D 85  ? VAL D 89  ? GLN L 79  VAL L 83  5 ? 5 
HELX_P HELX_P16 AB7 SER D 127 ? SER D 133 ? SER L 121 SER L 127 1 ? 7 
HELX_P HELX_P17 AB8 LYS D 189 ? GLU D 193 ? LYS L 183 GLU L 187 1 ? 5 
HELX_P HELX_P18 AB9 GLU E 79  ? PHE E 83  ? GLU G 79  PHE G 83  5 ? 5 
HELX_P HELX_P19 AC1 SER E 121 ? LYS E 126 ? SER G 121 LYS G 126 1 ? 6 
HELX_P HELX_P20 AC2 LYS E 183 ? GLU E 187 ? LYS G 183 GLU G 187 1 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 4   SG  ? ? ? 1_555 A CYS 29  SG ? ? A CYS 336 A CYS 361 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf2  disulf ?    ? A CYS 47  SG  ? ? ? 1_555 A CYS 100 SG ? ? A CYS 379 A CYS 432 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf3  disulf ?    ? A CYS 59  SG  ? ? ? 1_555 A CYS 193 SG ? ? A CYS 391 A CYS 525 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf4  disulf ?    ? A CYS 148 SG  ? ? ? 1_555 A CYS 156 SG ? ? A CYS 480 A CYS 488 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf5  disulf ?    ? B CYS 22  SG  ? ? ? 1_555 B CYS 96  SG ? ? H CYS 22  H CYS 92  1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf6  disulf ?    ? B CYS 146 SG  ? ? ? 1_555 B CYS 202 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf7  disulf ?    ? C CYS 22  SG  ? ? ? 1_555 C CYS 95  SG ? ? F CYS 22  F CYS 92  1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf8  disulf ?    ? C CYS 144 SG  ? ? ? 1_555 C CYS 200 SG ? ? F CYS 140 F CYS 196 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf9  disulf ?    ? D CYS 23  SG  ? ? ? 1_555 D CYS 94  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.040 ? ?               
disulf10 disulf ?    ? D CYS 140 SG  ? ? ? 1_555 D CYS 200 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf11 disulf ?    ? E CYS 23  SG  ? ? ? 1_555 E CYS 88  SG ? ? G CYS 23  G CYS 88  1_555 ? ? ? ? ? ? ? 2.040 ? ?               
disulf12 disulf ?    ? E CYS 134 SG  ? ? ? 1_555 E CYS 194 SG ? ? G CYS 134 G CYS 194 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
covale1  covale one  ? A ASN 11  ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 343 B NAG 1   1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale2  covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? B NAG 1   B NAG 2   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale3  covale both ? F NAG .   O4  ? ? ? 1_555 F BMA .   C1 ? ? B NAG 2   B BMA 3   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG F .   ? ASN A 11  ? NAG B 1   ? 1_555 ASN A 343 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  CYS A 4   ? CYS A 29  ? CYS A 336 ? 1_555 CYS A 361 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
3  CYS A 47  ? CYS A 100 ? CYS A 379 ? 1_555 CYS A 432 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4  CYS A 59  ? CYS A 193 ? CYS A 391 ? 1_555 CYS A 525 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS A 148 ? CYS A 156 ? CYS A 480 ? 1_555 CYS A 488 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS B 22  ? CYS B 96  ? CYS H 22  ? 1_555 CYS H 92  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS B 146 ? CYS B 202 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS C 22  ? CYS C 95  ? CYS F 22  ? 1_555 CYS F 92  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS C 144 ? CYS C 200 ? CYS F 140 ? 1_555 CYS F 196 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS D 23  ? CYS D 94  ? CYS L 23  ? 1_555 CYS L 88  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS D 140 ? CYS D 200 ? CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS E 23  ? CYS E 88  ? CYS G 23  ? 1_555 CYS G 88  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS E 134 ? CYS E 194 ? CYS G 134 ? 1_555 CYS G 194 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1  PHE 152 B . ? PHE 146 H PRO 153 B ? PRO 147 H 1 -3.00 
2  GLU 154 B . ? GLU 148 H PRO 155 B ? PRO 149 H 1 -1.44 
3  PHE 150 C . ? PHE 146 F PRO 151 C ? PRO 147 F 1 -4.70 
4  GLU 152 C . ? GLU 148 F PRO 153 C ? PRO 149 F 1 -1.05 
5  SER 7   D . ? SER 7   L PRO 8   D ? PRO 8   L 1 -3.60 
6  THR 100 D . ? THR 94  L PRO 101 D ? PRO 95  L 1 -0.04 
7  TYR 146 D . ? TYR 140 L PRO 147 D ? PRO 141 L 1 1.10  
8  SER 7   E . ? SER 7   G PRO 8   E ? PRO 8   G 1 -0.49 
9  SER 94  E . ? SER 94  G PRO 95  E ? PRO 95  G 1 -1.70 
10 TYR 140 E . ? TYR 140 G PRO 141 E ? PRO 141 G 1 3.08  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 4 ? 
AA6 ? 6 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 3 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
AB6 ? 4 ? 
AB7 ? 3 ? 
AB8 ? 4 ? 
AB9 ? 6 ? 
AC1 ? 4 ? 
AC2 ? 4 ? 
AC3 ? 4 ? 
AC4 ? 4 ? 
AC5 ? 6 ? 
AC6 ? 4 ? 
AC7 ? 4 ? 
AC8 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? parallel      
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AB9 4 5 ? anti-parallel 
AB9 5 6 ? anti-parallel 
AC1 1 2 ? parallel      
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? parallel      
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC5 4 5 ? anti-parallel 
AC5 5 6 ? anti-parallel 
AC6 1 2 ? parallel      
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC8 2 3 ? anti-parallel 
AC8 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ASN A 22  ? ILE A 26  ? ASN A 354 ILE A 358 
AA1 2 ASN A 62  ? ARG A 71  ? ASN A 394 ARG A 403 
AA1 3 PRO A 175 ? GLU A 184 ? PRO A 507 GLU A 516 
AA1 4 GLY A 99  ? ASN A 105 ? GLY A 431 ASN A 437 
AA1 5 THR A 44  ? TYR A 48  ? THR A 376 TYR A 380 
AA2 1 CYS A 29  ? VAL A 30  ? CYS A 361 VAL A 362 
AA2 2 VAL A 192 ? CYS A 193 ? VAL A 524 CYS A 525 
AA2 3 CYS A 59  ? PHE A 60  ? CYS A 391 PHE A 392 
AA3 1 LEU A 120 ? ARG A 122 ? LEU A 452 ARG A 454 
AA3 2 LEU A 160 ? SER A 162 ? LEU A 492 SER A 494 
AA4 1 TYR A 141 ? GLN A 142 ? TYR A 473 GLN A 474 
AA4 2 CYS A 156 ? TYR A 157 ? CYS A 488 TYR A 489 
AA5 1 GLN B 3   ? GLN B 6   ? GLN H 3   GLN H 6   
AA5 2 LEU B 18  ? SER B 25  ? LEU H 18  SER H 25  
AA5 3 THR B 78  ? TRP B 83  ? THR H 77  TRP H 82  
AA5 4 THR B 69  ? ASP B 73  ? THR H 68  ASP H 72  
AA6 1 GLU B 10  ? LYS B 12  ? GLU H 10  LYS H 12  
AA6 2 THR B 113 ? VAL B 117 ? THR H 107 VAL H 111 
AA6 3 ALA B 92  ? SER B 100 ? ALA H 88  SER H 96  
AA6 4 TYR B 32  ? GLN B 39  ? TYR H 32  GLN H 39  
AA6 5 GLU B 46  ? TYR B 52  ? GLU H 46  TYR H 52  
AA6 6 ASP B 57  ? TYR B 60  ? ASP H 56  TYR H 59  
AA7 1 GLU B 10  ? LYS B 12  ? GLU H 10  LYS H 12  
AA7 2 THR B 113 ? VAL B 117 ? THR H 107 VAL H 111 
AA7 3 ALA B 92  ? SER B 100 ? ALA H 88  SER H 96  
AA7 4 VAL B 108 ? TRP B 109 ? VAL H 102 TRP H 103 
AA8 1 SER B 126 ? LEU B 130 ? SER H 120 LEU H 124 
AA8 2 THR B 141 ? TYR B 151 ? THR H 135 TYR H 145 
AA8 3 TYR B 182 ? PRO B 191 ? TYR H 176 PRO H 185 
AA8 4 VAL B 169 ? THR B 171 ? VAL H 163 THR H 165 
AA9 1 SER B 126 ? LEU B 130 ? SER H 120 LEU H 124 
AA9 2 THR B 141 ? TYR B 151 ? THR H 135 TYR H 145 
AA9 3 TYR B 182 ? PRO B 191 ? TYR H 176 PRO H 185 
AA9 4 VAL B 175 ? LEU B 176 ? VAL H 169 LEU H 170 
AB1 1 THR B 157 ? TRP B 160 ? THR H 151 TRP H 154 
AB1 2 TYR B 200 ? HIS B 206 ? TYR H 194 HIS H 200 
AB1 3 THR B 211 ? VAL B 217 ? THR H 205 VAL H 211 
AB2 1 GLN C 3   ? SER C 7   ? GLN F 3   SER F 7   
AB2 2 LEU C 18  ? SER C 25  ? LEU F 18  SER F 25  
AB2 3 THR C 77  ? MET C 82  ? THR F 77  MET F 82  
AB2 4 PHE C 67  ? ASP C 72  ? PHE F 67  ASP F 72  
AB3 1 LEU C 11  ? ILE C 12  ? LEU F 11  ILE F 12  
AB3 2 THR C 111 ? VAL C 115 ? THR F 107 VAL F 111 
AB3 3 ALA C 91  ? PHE C 99  ? ALA F 88  PHE F 96  
AB3 4 TYR C 33  ? GLN C 39  ? TYR F 33  GLN F 39  
AB3 5 LEU C 45  ? ILE C 51  ? LEU F 45  ILE F 51  
AB3 6 THR C 57  ? TYR C 59  ? THR F 57  TYR F 59  
AB4 1 LEU C 11  ? ILE C 12  ? LEU F 11  ILE F 12  
AB4 2 THR C 111 ? VAL C 115 ? THR F 107 VAL F 111 
AB4 3 ALA C 91  ? PHE C 99  ? ALA F 88  PHE F 96  
AB4 4 TYR C 103 ? TRP C 107 ? TYR F 100 TRP F 103 
AB5 1 SER C 124 ? LEU C 128 ? SER F 120 LEU F 124 
AB5 2 ALA C 140 ? TYR C 149 ? ALA F 136 TYR F 145 
AB5 3 TYR C 180 ? VAL C 188 ? TYR F 176 VAL F 184 
AB5 4 HIS C 168 ? THR C 169 ? HIS F 164 THR F 165 
AB6 1 SER C 124 ? LEU C 128 ? SER F 120 LEU F 124 
AB6 2 ALA C 140 ? TYR C 149 ? ALA F 136 TYR F 145 
AB6 3 TYR C 180 ? VAL C 188 ? TYR F 176 VAL F 184 
AB6 4 VAL C 173 ? LEU C 174 ? VAL F 169 LEU F 170 
AB7 1 THR C 155 ? TRP C 158 ? THR F 151 TRP F 154 
AB7 2 ILE C 199 ? HIS C 204 ? ILE F 195 HIS F 200 
AB7 3 THR C 209 ? LYS C 214 ? THR F 205 LYS F 210 
AB8 1 MET D 4   ? SER D 7   ? MET L 4   SER L 7   
AB8 2 ALA D 19  ? SER D 25  ? ALA L 19  SER L 25  
AB8 3 ASP D 76  ? ILE D 81  ? ASP L 70  ILE L 75  
AB8 4 PHE D 68  ? SER D 73  ? PHE L 62  SER L 67  
AB9 1 SER D 10  ? VAL D 13  ? SER L 10  VAL L 13  
AB9 2 THR D 108 ? ILE D 112 ? THR L 102 ILE L 106 
AB9 3 ALA D 90  ? GLN D 96  ? ALA L 84  GLN L 90  
AB9 4 LEU D 39  ? GLN D 44  ? LEU L 33  GLN L 38  
AB9 5 LYS D 51  ? TYR D 55  ? LYS L 45  TYR L 49  
AB9 6 ILE D 59  ? ARG D 60  ? ILE L 53  ARG L 54  
AC1 1 SER D 10  ? VAL D 13  ? SER L 10  VAL L 13  
AC1 2 THR D 108 ? ILE D 112 ? THR L 102 ILE L 106 
AC1 3 ALA D 90  ? GLN D 96  ? ALA L 84  GLN L 90  
AC1 4 THR D 103 ? PHE D 104 ? THR L 97  PHE L 98  
AC2 1 SER D 120 ? PHE D 124 ? SER L 114 PHE L 118 
AC2 2 THR D 135 ? PHE D 145 ? THR L 129 PHE L 139 
AC2 3 TYR D 179 ? SER D 188 ? TYR L 173 SER L 182 
AC2 4 SER D 165 ? VAL D 169 ? SER L 159 VAL L 163 
AC3 1 ALA D 159 ? LEU D 160 ? ALA L 153 LEU L 154 
AC3 2 LYS D 151 ? VAL D 156 ? LYS L 145 VAL L 150 
AC3 3 VAL D 197 ? THR D 203 ? VAL L 191 THR L 197 
AC3 4 VAL D 211 ? ASN D 216 ? VAL L 205 ASN L 210 
AC4 1 LEU E 4   ? SER E 7   ? LEU G 4   SER G 7   
AC4 2 ALA E 19  ? ALA E 25  ? ALA G 19  ALA G 25  
AC4 3 ASP E 70  ? ILE E 75  ? ASP G 70  ILE G 75  
AC4 4 PHE E 62  ? SER E 67  ? PHE G 62  SER G 67  
AC5 1 THR E 10  ? LEU E 13  ? THR G 10  LEU G 13  
AC5 2 THR E 102 ? ILE E 106 ? THR G 102 ILE G 106 
AC5 3 ALA E 84  ? GLN E 90  ? ALA G 84  GLN G 90  
AC5 4 LEU E 33  ? GLN E 38  ? LEU G 33  GLN G 38  
AC5 5 ARG E 45  ? TYR E 49  ? ARG G 45  TYR G 49  
AC5 6 SER E 53  ? ARG E 54  ? SER G 53  ARG G 54  
AC6 1 THR E 10  ? LEU E 13  ? THR G 10  LEU G 13  
AC6 2 THR E 102 ? ILE E 106 ? THR G 102 ILE G 106 
AC6 3 ALA E 84  ? GLN E 90  ? ALA G 84  GLN G 90  
AC6 4 THR E 97  ? PHE E 98  ? THR G 97  PHE G 98  
AC7 1 SER E 114 ? PHE E 118 ? SER G 114 PHE G 118 
AC7 2 THR E 129 ? PHE E 139 ? THR G 129 PHE G 139 
AC7 3 TYR E 173 ? SER E 182 ? TYR G 173 SER G 182 
AC7 4 SER E 159 ? VAL E 163 ? SER G 159 VAL G 163 
AC8 1 ALA E 153 ? GLN E 155 ? ALA G 153 GLN G 155 
AC8 2 LYS E 145 ? VAL E 150 ? LYS G 145 VAL G 150 
AC8 3 VAL E 191 ? THR E 197 ? VAL G 191 THR G 197 
AC8 4 VAL E 205 ? ASN E 210 ? VAL G 205 ASN G 210 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 26  ? N ILE A 358 O VAL A 63  ? O VAL A 395 
AA1 2 3 N TYR A 64  ? N TYR A 396 O SER A 182 ? O SER A 514 
AA1 3 4 O VAL A 179 ? O VAL A 511 N ILE A 102 ? N ILE A 434 
AA1 4 5 O VAL A 101 ? O VAL A 433 N LYS A 46  ? N LYS A 378 
AA2 1 2 N CYS A 29  ? N CYS A 361 O CYS A 193 ? O CYS A 525 
AA2 2 3 O VAL A 192 ? O VAL A 524 N PHE A 60  ? N PHE A 392 
AA3 1 2 N TYR A 121 ? N TYR A 453 O GLN A 161 ? O GLN A 493 
AA4 1 2 N TYR A 141 ? N TYR A 473 O TYR A 157 ? O TYR A 489 
AA5 1 2 N VAL B 5   ? N VAL H 5   O LYS B 23  ? O LYS H 23  
AA5 2 3 N CYS B 22  ? N CYS H 22  O ALA B 79  ? O ALA H 78  
AA5 3 4 O TYR B 80  ? O TYR H 79  N SER B 71  ? N SER H 70  
AA6 1 2 N GLU B 10  ? N GLU H 10  O THR B 114 ? O THR H 108 
AA6 2 3 O THR B 113 ? O THR H 107 N TYR B 94  ? N TYR H 90  
AA6 3 4 O ALA B 97  ? O ALA H 93  N GLY B 35  ? N GLY H 35  
AA6 4 5 N ARG B 38  ? N ARG H 38  O GLU B 46  ? O GLU H 46  
AA6 5 6 N ILE B 50  ? N ILE H 50  O ARG B 59  ? O ARG H 58  
AA7 1 2 N GLU B 10  ? N GLU H 10  O THR B 114 ? O THR H 108 
AA7 2 3 O THR B 113 ? O THR H 107 N TYR B 94  ? N TYR H 90  
AA7 3 4 N GLY B 98  ? N GLY H 94  O VAL B 108 ? O VAL H 102 
AA8 1 2 N PHE B 128 ? N PHE H 122 O LEU B 147 ? O LEU H 141 
AA8 2 3 N ALA B 142 ? N ALA H 136 O VAL B 190 ? O VAL H 184 
AA8 3 4 O VAL B 187 ? O VAL H 181 N HIS B 170 ? N HIS H 164 
AA9 1 2 N PHE B 128 ? N PHE H 122 O LEU B 147 ? O LEU H 141 
AA9 2 3 N ALA B 142 ? N ALA H 136 O VAL B 190 ? O VAL H 184 
AA9 3 4 O SER B 183 ? O SER H 177 N VAL B 175 ? N VAL H 169 
AB1 1 2 N SER B 159 ? N SER H 153 O ASN B 203 ? O ASN H 197 
AB1 2 3 N HIS B 206 ? N HIS H 200 O THR B 211 ? O THR H 205 
AB2 1 2 N SER C 7   ? N SER F 7   O SER C 21  ? O SER F 21  
AB2 2 3 N LEU C 18  ? N LEU F 18  O MET C 82  ? O MET F 82  
AB2 3 4 O TYR C 79  ? O TYR F 79  N SER C 70  ? N SER F 70  
AB3 1 2 N ILE C 12  ? N ILE F 12  O THR C 114 ? O THR F 110 
AB3 2 3 O THR C 111 ? O THR F 107 N TYR C 93  ? N TYR F 90  
AB3 3 4 O TYR C 94  ? O TYR F 91  N VAL C 37  ? N VAL F 37  
AB3 4 5 N MET C 34  ? N MET F 34  O ILE C 51  ? O ILE F 51  
AB3 5 6 N VAL C 50  ? N VAL F 50  O PHE C 58  ? O PHE F 58  
AB4 1 2 N ILE C 12  ? N ILE F 12  O THR C 114 ? O THR F 110 
AB4 2 3 O THR C 111 ? O THR F 107 N TYR C 93  ? N TYR F 90  
AB4 3 4 N PHE C 99  ? N PHE F 96  O TYR C 103 ? O TYR F 100 
AB5 1 2 N PHE C 126 ? N PHE F 122 O LEU C 145 ? O LEU F 141 
AB5 2 3 N VAL C 146 ? N VAL F 142 O LEU C 182 ? O LEU F 178 
AB5 3 4 O VAL C 185 ? O VAL F 181 N HIS C 168 ? N HIS F 164 
AB6 1 2 N PHE C 126 ? N PHE F 122 O LEU C 145 ? O LEU F 141 
AB6 2 3 N VAL C 146 ? N VAL F 142 O LEU C 182 ? O LEU F 178 
AB6 3 4 O SER C 181 ? O SER F 177 N VAL C 173 ? N VAL F 169 
AB7 1 2 N SER C 157 ? N SER F 153 O ASN C 201 ? O ASN F 197 
AB7 2 3 N VAL C 202 ? N VAL F 198 O VAL C 211 ? O VAL F 207 
AB8 1 2 N THR D 5   ? N THR L 5   O LYS D 24  ? O LYS L 24  
AB8 2 3 N ILE D 21  ? N ILE L 21  O LEU D 79  ? O LEU L 73  
AB8 3 4 O THR D 80  ? O THR L 74  N SER D 69  ? N SER L 63  
AB9 1 2 N LEU D 11  ? N LEU L 11  O LYS D 109 ? O LYS L 103 
AB9 2 3 O LEU D 110 ? O LEU L 104 N ALA D 90  ? N ALA L 84  
AB9 3 4 O TYR D 93  ? O TYR L 87  N TYR D 42  ? N TYR L 36  
AB9 4 5 N GLN D 43  ? N GLN L 37  O LYS D 51  ? O LYS L 45  
AB9 5 6 N TYR D 55  ? N TYR L 49  O ILE D 59  ? O ILE L 53  
AC1 1 2 N LEU D 11  ? N LEU L 11  O LYS D 109 ? O LYS L 103 
AC1 2 3 O LEU D 110 ? O LEU L 104 N ALA D 90  ? N ALA L 84  
AC1 3 4 N GLN D 96  ? N GLN L 90  O THR D 103 ? O THR L 97  
AC2 1 2 N PHE D 122 ? N PHE L 116 O LEU D 141 ? O LEU L 135 
AC2 2 3 N LEU D 142 ? N LEU L 136 O LEU D 181 ? O LEU L 175 
AC2 3 4 O SER D 182 ? O SER L 176 N SER D 168 ? N SER L 162 
AC3 1 2 O ALA D 159 ? O ALA L 153 N VAL D 156 ? N VAL L 150 
AC3 2 3 N LYS D 155 ? N LYS L 149 O ALA D 199 ? O ALA L 193 
AC3 3 4 N VAL D 202 ? N VAL L 196 O VAL D 211 ? O VAL L 205 
AC4 1 2 N THR E 5   ? N THR G 5   O ARG E 24  ? O ARG G 24  
AC4 2 3 N ALA E 19  ? N ALA G 19  O ILE E 75  ? O ILE G 75  
AC4 3 4 O THR E 74  ? O THR G 74  N SER E 63  ? N SER G 63  
AC5 1 2 N LEU E 11  ? N LEU G 11  O LYS E 103 ? O LYS G 103 
AC5 2 3 O LEU E 104 ? O LEU G 104 N ALA E 84  ? N ALA G 84  
AC5 3 4 O TYR E 87  ? O TYR G 87  N TYR E 36  ? N TYR G 36  
AC5 4 5 N GLN E 37  ? N GLN G 37  O ARG E 45  ? O ARG G 45  
AC5 5 6 N TYR E 49  ? N TYR G 49  O SER E 53  ? O SER G 53  
AC6 1 2 N LEU E 11  ? N LEU G 11  O LYS E 103 ? O LYS G 103 
AC6 2 3 O LEU E 104 ? O LEU G 104 N ALA E 84  ? N ALA G 84  
AC6 3 4 N GLN E 90  ? N GLN G 90  O THR E 97  ? O THR G 97  
AC7 1 2 N PHE E 116 ? N PHE G 116 O LEU E 135 ? O LEU G 135 
AC7 2 3 N ALA E 130 ? N ALA G 130 O LEU E 181 ? O LEU G 181 
AC7 3 4 O SER E 176 ? O SER G 176 N SER E 162 ? N SER G 162 
AC8 1 2 O GLN E 155 ? O GLN G 155 N TRP E 148 ? N TRP G 148 
AC8 2 3 N LYS E 145 ? N LYS G 145 O THR E 197 ? O THR G 197 
AC8 3 4 N TYR E 192 ? N TYR G 192 O PHE E 209 ? O PHE G 209 
# 
_pdbx_entry_details.entry_id                   9CPU 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   G SER 76  ? ? O G HOH 301 ? ? 2.12 
2 1 O   G GLN 124 ? ? O G HOH 302 ? ? 2.13 
3 1 OE1 H GLN 81  ? ? O H HOH 301 ? ? 2.16 
4 1 OE1 G GLN 90  ? ? O G HOH 303 ? ? 2.16 
5 1 OG  H SER 70  ? ? O H HOH 301 ? ? 2.18 
6 1 NH1 G ARG 61  ? ? O G HOH 301 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 428 ? ? -99.45  36.34   
2 1 ASN A 487 ? ? 57.27   19.84   
3 1 ASP H 144 ? ? 60.55   64.73   
4 1 SER F 156 ? ? 57.54   -125.03 
5 1 LEU F 189 ? ? 40.01   -130.38 
6 1 ALA L 51  ? ? 72.28   -10.56  
7 1 SER L 52  ? ? -140.86 -16.26  
8 1 ALA G 51  ? ? 59.87   -3.80   
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    L 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     385 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   J 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A LYS 529 ? A LYS 197 
2  1 Y 1 A SER 530 ? A SER 198 
3  1 Y 1 A GLY 531 ? A GLY 199 
4  1 Y 1 A HIS 532 ? A HIS 200 
5  1 Y 1 A HIS 533 ? A HIS 201 
6  1 Y 1 A HIS 534 ? A HIS 202 
7  1 Y 1 A HIS 535 ? A HIS 203 
8  1 Y 1 A HIS 536 ? A HIS 204 
9  1 Y 1 A HIS 537 ? A HIS 205 
10 1 Y 1 H LYS 129 ? B LYS 135 
11 1 Y 1 H SER 130 ? B SER 136 
12 1 Y 1 H THR 131 ? B THR 137 
13 1 Y 1 H LYS 214 ? B LYS 220 
14 1 Y 1 H SER 215 ? B SER 221 
15 1 Y 1 H CYS 216 ? B CYS 222 
16 1 Y 1 F LYS 129 ? C LYS 133 
17 1 Y 1 F SER 130 ? C SER 134 
18 1 Y 1 F THR 131 ? C THR 135 
19 1 Y 1 F SER 132 ? C SER 136 
20 1 Y 1 F GLY 133 ? C GLY 137 
21 1 Y 1 F GLY 134 ? C GLY 138 
22 1 Y 1 F SER 215 ? C SER 219 
23 1 Y 1 F CYS 216 ? C CYS 220 
24 1 Y 1 L CYS 214 ? D CYS 220 
25 1 Y 1 G GLY 212 ? E GLY 212 
26 1 Y 1 G GLU 213 ? E GLU 213 
27 1 Y 1 G CYS 214 ? E CYS 214 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
HOH O    O N N 182 
HOH H1   H N N 183 
HOH H2   H N N 184 
ILE N    N N N 185 
ILE CA   C N S 186 
ILE C    C N N 187 
ILE O    O N N 188 
ILE CB   C N S 189 
ILE CG1  C N N 190 
ILE CG2  C N N 191 
ILE CD1  C N N 192 
ILE OXT  O N N 193 
ILE H    H N N 194 
ILE H2   H N N 195 
ILE HA   H N N 196 
ILE HB   H N N 197 
ILE HG12 H N N 198 
ILE HG13 H N N 199 
ILE HG21 H N N 200 
ILE HG22 H N N 201 
ILE HG23 H N N 202 
ILE HD11 H N N 203 
ILE HD12 H N N 204 
ILE HD13 H N N 205 
ILE HXT  H N N 206 
LEU N    N N N 207 
LEU CA   C N S 208 
LEU C    C N N 209 
LEU O    O N N 210 
LEU CB   C N N 211 
LEU CG   C N N 212 
LEU CD1  C N N 213 
LEU CD2  C N N 214 
LEU OXT  O N N 215 
LEU H    H N N 216 
LEU H2   H N N 217 
LEU HA   H N N 218 
LEU HB2  H N N 219 
LEU HB3  H N N 220 
LEU HG   H N N 221 
LEU HD11 H N N 222 
LEU HD12 H N N 223 
LEU HD13 H N N 224 
LEU HD21 H N N 225 
LEU HD22 H N N 226 
LEU HD23 H N N 227 
LEU HXT  H N N 228 
LYS N    N N N 229 
LYS CA   C N S 230 
LYS C    C N N 231 
LYS O    O N N 232 
LYS CB   C N N 233 
LYS CG   C N N 234 
LYS CD   C N N 235 
LYS CE   C N N 236 
LYS NZ   N N N 237 
LYS OXT  O N N 238 
LYS H    H N N 239 
LYS H2   H N N 240 
LYS HA   H N N 241 
LYS HB2  H N N 242 
LYS HB3  H N N 243 
LYS HG2  H N N 244 
LYS HG3  H N N 245 
LYS HD2  H N N 246 
LYS HD3  H N N 247 
LYS HE2  H N N 248 
LYS HE3  H N N 249 
LYS HZ1  H N N 250 
LYS HZ2  H N N 251 
LYS HZ3  H N N 252 
LYS HXT  H N N 253 
MET N    N N N 254 
MET CA   C N S 255 
MET C    C N N 256 
MET O    O N N 257 
MET CB   C N N 258 
MET CG   C N N 259 
MET SD   S N N 260 
MET CE   C N N 261 
MET OXT  O N N 262 
MET H    H N N 263 
MET H2   H N N 264 
MET HA   H N N 265 
MET HB2  H N N 266 
MET HB3  H N N 267 
MET HG2  H N N 268 
MET HG3  H N N 269 
MET HE1  H N N 270 
MET HE2  H N N 271 
MET HE3  H N N 272 
MET HXT  H N N 273 
NAG C1   C N R 274 
NAG C2   C N R 275 
NAG C3   C N R 276 
NAG C4   C N S 277 
NAG C5   C N R 278 
NAG C6   C N N 279 
NAG C7   C N N 280 
NAG C8   C N N 281 
NAG N2   N N N 282 
NAG O1   O N N 283 
NAG O3   O N N 284 
NAG O4   O N N 285 
NAG O5   O N N 286 
NAG O6   O N N 287 
NAG O7   O N N 288 
NAG H1   H N N 289 
NAG H2   H N N 290 
NAG H3   H N N 291 
NAG H4   H N N 292 
NAG H5   H N N 293 
NAG H61  H N N 294 
NAG H62  H N N 295 
NAG H81  H N N 296 
NAG H82  H N N 297 
NAG H83  H N N 298 
NAG HN2  H N N 299 
NAG HO1  H N N 300 
NAG HO3  H N N 301 
NAG HO4  H N N 302 
NAG HO6  H N N 303 
PHE N    N N N 304 
PHE CA   C N S 305 
PHE C    C N N 306 
PHE O    O N N 307 
PHE CB   C N N 308 
PHE CG   C Y N 309 
PHE CD1  C Y N 310 
PHE CD2  C Y N 311 
PHE CE1  C Y N 312 
PHE CE2  C Y N 313 
PHE CZ   C Y N 314 
PHE OXT  O N N 315 
PHE H    H N N 316 
PHE H2   H N N 317 
PHE HA   H N N 318 
PHE HB2  H N N 319 
PHE HB3  H N N 320 
PHE HD1  H N N 321 
PHE HD2  H N N 322 
PHE HE1  H N N 323 
PHE HE2  H N N 324 
PHE HZ   H N N 325 
PHE HXT  H N N 326 
PRO N    N N N 327 
PRO CA   C N S 328 
PRO C    C N N 329 
PRO O    O N N 330 
PRO CB   C N N 331 
PRO CG   C N N 332 
PRO CD   C N N 333 
PRO OXT  O N N 334 
PRO H    H N N 335 
PRO HA   H N N 336 
PRO HB2  H N N 337 
PRO HB3  H N N 338 
PRO HG2  H N N 339 
PRO HG3  H N N 340 
PRO HD2  H N N 341 
PRO HD3  H N N 342 
PRO HXT  H N N 343 
SER N    N N N 344 
SER CA   C N S 345 
SER C    C N N 346 
SER O    O N N 347 
SER CB   C N N 348 
SER OG   O N N 349 
SER OXT  O N N 350 
SER H    H N N 351 
SER H2   H N N 352 
SER HA   H N N 353 
SER HB2  H N N 354 
SER HB3  H N N 355 
SER HG   H N N 356 
SER HXT  H N N 357 
THR N    N N N 358 
THR CA   C N S 359 
THR C    C N N 360 
THR O    O N N 361 
THR CB   C N R 362 
THR OG1  O N N 363 
THR CG2  C N N 364 
THR OXT  O N N 365 
THR H    H N N 366 
THR H2   H N N 367 
THR HA   H N N 368 
THR HB   H N N 369 
THR HG1  H N N 370 
THR HG21 H N N 371 
THR HG22 H N N 372 
THR HG23 H N N 373 
THR HXT  H N N 374 
TRP N    N N N 375 
TRP CA   C N S 376 
TRP C    C N N 377 
TRP O    O N N 378 
TRP CB   C N N 379 
TRP CG   C Y N 380 
TRP CD1  C Y N 381 
TRP CD2  C Y N 382 
TRP NE1  N Y N 383 
TRP CE2  C Y N 384 
TRP CE3  C Y N 385 
TRP CZ2  C Y N 386 
TRP CZ3  C Y N 387 
TRP CH2  C Y N 388 
TRP OXT  O N N 389 
TRP H    H N N 390 
TRP H2   H N N 391 
TRP HA   H N N 392 
TRP HB2  H N N 393 
TRP HB3  H N N 394 
TRP HD1  H N N 395 
TRP HE1  H N N 396 
TRP HE3  H N N 397 
TRP HZ2  H N N 398 
TRP HZ3  H N N 399 
TRP HH2  H N N 400 
TRP HXT  H N N 401 
TYR N    N N N 402 
TYR CA   C N S 403 
TYR C    C N N 404 
TYR O    O N N 405 
TYR CB   C N N 406 
TYR CG   C Y N 407 
TYR CD1  C Y N 408 
TYR CD2  C Y N 409 
TYR CE1  C Y N 410 
TYR CE2  C Y N 411 
TYR CZ   C Y N 412 
TYR OH   O N N 413 
TYR OXT  O N N 414 
TYR H    H N N 415 
TYR H2   H N N 416 
TYR HA   H N N 417 
TYR HB2  H N N 418 
TYR HB3  H N N 419 
TYR HD1  H N N 420 
TYR HD2  H N N 421 
TYR HE1  H N N 422 
TYR HE2  H N N 423 
TYR HH   H N N 424 
TYR HXT  H N N 425 
VAL N    N N N 426 
VAL CA   C N S 427 
VAL C    C N N 428 
VAL O    O N N 429 
VAL CB   C N N 430 
VAL CG1  C N N 431 
VAL CG2  C N N 432 
VAL OXT  O N N 433 
VAL H    H N N 434 
VAL H2   H N N 435 
VAL HA   H N N 436 
VAL HB   H N N 437 
VAL HG11 H N N 438 
VAL HG12 H N N 439 
VAL HG13 H N N 440 
VAL HG21 H N N 441 
VAL HG22 H N N 442 
VAL HG23 H N N 443 
VAL HXT  H N N 444 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
HOH O   H1   sing N N 174 
HOH O   H2   sing N N 175 
ILE N   CA   sing N N 176 
ILE N   H    sing N N 177 
ILE N   H2   sing N N 178 
ILE CA  C    sing N N 179 
ILE CA  CB   sing N N 180 
ILE CA  HA   sing N N 181 
ILE C   O    doub N N 182 
ILE C   OXT  sing N N 183 
ILE CB  CG1  sing N N 184 
ILE CB  CG2  sing N N 185 
ILE CB  HB   sing N N 186 
ILE CG1 CD1  sing N N 187 
ILE CG1 HG12 sing N N 188 
ILE CG1 HG13 sing N N 189 
ILE CG2 HG21 sing N N 190 
ILE CG2 HG22 sing N N 191 
ILE CG2 HG23 sing N N 192 
ILE CD1 HD11 sing N N 193 
ILE CD1 HD12 sing N N 194 
ILE CD1 HD13 sing N N 195 
ILE OXT HXT  sing N N 196 
LEU N   CA   sing N N 197 
LEU N   H    sing N N 198 
LEU N   H2   sing N N 199 
LEU CA  C    sing N N 200 
LEU CA  CB   sing N N 201 
LEU CA  HA   sing N N 202 
LEU C   O    doub N N 203 
LEU C   OXT  sing N N 204 
LEU CB  CG   sing N N 205 
LEU CB  HB2  sing N N 206 
LEU CB  HB3  sing N N 207 
LEU CG  CD1  sing N N 208 
LEU CG  CD2  sing N N 209 
LEU CG  HG   sing N N 210 
LEU CD1 HD11 sing N N 211 
LEU CD1 HD12 sing N N 212 
LEU CD1 HD13 sing N N 213 
LEU CD2 HD21 sing N N 214 
LEU CD2 HD22 sing N N 215 
LEU CD2 HD23 sing N N 216 
LEU OXT HXT  sing N N 217 
LYS N   CA   sing N N 218 
LYS N   H    sing N N 219 
LYS N   H2   sing N N 220 
LYS CA  C    sing N N 221 
LYS CA  CB   sing N N 222 
LYS CA  HA   sing N N 223 
LYS C   O    doub N N 224 
LYS C   OXT  sing N N 225 
LYS CB  CG   sing N N 226 
LYS CB  HB2  sing N N 227 
LYS CB  HB3  sing N N 228 
LYS CG  CD   sing N N 229 
LYS CG  HG2  sing N N 230 
LYS CG  HG3  sing N N 231 
LYS CD  CE   sing N N 232 
LYS CD  HD2  sing N N 233 
LYS CD  HD3  sing N N 234 
LYS CE  NZ   sing N N 235 
LYS CE  HE2  sing N N 236 
LYS CE  HE3  sing N N 237 
LYS NZ  HZ1  sing N N 238 
LYS NZ  HZ2  sing N N 239 
LYS NZ  HZ3  sing N N 240 
LYS OXT HXT  sing N N 241 
MET N   CA   sing N N 242 
MET N   H    sing N N 243 
MET N   H2   sing N N 244 
MET CA  C    sing N N 245 
MET CA  CB   sing N N 246 
MET CA  HA   sing N N 247 
MET C   O    doub N N 248 
MET C   OXT  sing N N 249 
MET CB  CG   sing N N 250 
MET CB  HB2  sing N N 251 
MET CB  HB3  sing N N 252 
MET CG  SD   sing N N 253 
MET CG  HG2  sing N N 254 
MET CG  HG3  sing N N 255 
MET SD  CE   sing N N 256 
MET CE  HE1  sing N N 257 
MET CE  HE2  sing N N 258 
MET CE  HE3  sing N N 259 
MET OXT HXT  sing N N 260 
NAG C1  C2   sing N N 261 
NAG C1  O1   sing N N 262 
NAG C1  O5   sing N N 263 
NAG C1  H1   sing N N 264 
NAG C2  C3   sing N N 265 
NAG C2  N2   sing N N 266 
NAG C2  H2   sing N N 267 
NAG C3  C4   sing N N 268 
NAG C3  O3   sing N N 269 
NAG C3  H3   sing N N 270 
NAG C4  C5   sing N N 271 
NAG C4  O4   sing N N 272 
NAG C4  H4   sing N N 273 
NAG C5  C6   sing N N 274 
NAG C5  O5   sing N N 275 
NAG C5  H5   sing N N 276 
NAG C6  O6   sing N N 277 
NAG C6  H61  sing N N 278 
NAG C6  H62  sing N N 279 
NAG C7  C8   sing N N 280 
NAG C7  N2   sing N N 281 
NAG C7  O7   doub N N 282 
NAG C8  H81  sing N N 283 
NAG C8  H82  sing N N 284 
NAG C8  H83  sing N N 285 
NAG N2  HN2  sing N N 286 
NAG O1  HO1  sing N N 287 
NAG O3  HO3  sing N N 288 
NAG O4  HO4  sing N N 289 
NAG O6  HO6  sing N N 290 
PHE N   CA   sing N N 291 
PHE N   H    sing N N 292 
PHE N   H2   sing N N 293 
PHE CA  C    sing N N 294 
PHE CA  CB   sing N N 295 
PHE CA  HA   sing N N 296 
PHE C   O    doub N N 297 
PHE C   OXT  sing N N 298 
PHE CB  CG   sing N N 299 
PHE CB  HB2  sing N N 300 
PHE CB  HB3  sing N N 301 
PHE CG  CD1  doub Y N 302 
PHE CG  CD2  sing Y N 303 
PHE CD1 CE1  sing Y N 304 
PHE CD1 HD1  sing N N 305 
PHE CD2 CE2  doub Y N 306 
PHE CD2 HD2  sing N N 307 
PHE CE1 CZ   doub Y N 308 
PHE CE1 HE1  sing N N 309 
PHE CE2 CZ   sing Y N 310 
PHE CE2 HE2  sing N N 311 
PHE CZ  HZ   sing N N 312 
PHE OXT HXT  sing N N 313 
PRO N   CA   sing N N 314 
PRO N   CD   sing N N 315 
PRO N   H    sing N N 316 
PRO CA  C    sing N N 317 
PRO CA  CB   sing N N 318 
PRO CA  HA   sing N N 319 
PRO C   O    doub N N 320 
PRO C   OXT  sing N N 321 
PRO CB  CG   sing N N 322 
PRO CB  HB2  sing N N 323 
PRO CB  HB3  sing N N 324 
PRO CG  CD   sing N N 325 
PRO CG  HG2  sing N N 326 
PRO CG  HG3  sing N N 327 
PRO CD  HD2  sing N N 328 
PRO CD  HD3  sing N N 329 
PRO OXT HXT  sing N N 330 
SER N   CA   sing N N 331 
SER N   H    sing N N 332 
SER N   H2   sing N N 333 
SER CA  C    sing N N 334 
SER CA  CB   sing N N 335 
SER CA  HA   sing N N 336 
SER C   O    doub N N 337 
SER C   OXT  sing N N 338 
SER CB  OG   sing N N 339 
SER CB  HB2  sing N N 340 
SER CB  HB3  sing N N 341 
SER OG  HG   sing N N 342 
SER OXT HXT  sing N N 343 
THR N   CA   sing N N 344 
THR N   H    sing N N 345 
THR N   H2   sing N N 346 
THR CA  C    sing N N 347 
THR CA  CB   sing N N 348 
THR CA  HA   sing N N 349 
THR C   O    doub N N 350 
THR C   OXT  sing N N 351 
THR CB  OG1  sing N N 352 
THR CB  CG2  sing N N 353 
THR CB  HB   sing N N 354 
THR OG1 HG1  sing N N 355 
THR CG2 HG21 sing N N 356 
THR CG2 HG22 sing N N 357 
THR CG2 HG23 sing N N 358 
THR OXT HXT  sing N N 359 
TRP N   CA   sing N N 360 
TRP N   H    sing N N 361 
TRP N   H2   sing N N 362 
TRP CA  C    sing N N 363 
TRP CA  CB   sing N N 364 
TRP CA  HA   sing N N 365 
TRP C   O    doub N N 366 
TRP C   OXT  sing N N 367 
TRP CB  CG   sing N N 368 
TRP CB  HB2  sing N N 369 
TRP CB  HB3  sing N N 370 
TRP CG  CD1  doub Y N 371 
TRP CG  CD2  sing Y N 372 
TRP CD1 NE1  sing Y N 373 
TRP CD1 HD1  sing N N 374 
TRP CD2 CE2  doub Y N 375 
TRP CD2 CE3  sing Y N 376 
TRP NE1 CE2  sing Y N 377 
TRP NE1 HE1  sing N N 378 
TRP CE2 CZ2  sing Y N 379 
TRP CE3 CZ3  doub Y N 380 
TRP CE3 HE3  sing N N 381 
TRP CZ2 CH2  doub Y N 382 
TRP CZ2 HZ2  sing N N 383 
TRP CZ3 CH2  sing Y N 384 
TRP CZ3 HZ3  sing N N 385 
TRP CH2 HH2  sing N N 386 
TRP OXT HXT  sing N N 387 
TYR N   CA   sing N N 388 
TYR N   H    sing N N 389 
TYR N   H2   sing N N 390 
TYR CA  C    sing N N 391 
TYR CA  CB   sing N N 392 
TYR CA  HA   sing N N 393 
TYR C   O    doub N N 394 
TYR C   OXT  sing N N 395 
TYR CB  CG   sing N N 396 
TYR CB  HB2  sing N N 397 
TYR CB  HB3  sing N N 398 
TYR CG  CD1  doub Y N 399 
TYR CG  CD2  sing Y N 400 
TYR CD1 CE1  sing Y N 401 
TYR CD1 HD1  sing N N 402 
TYR CD2 CE2  doub Y N 403 
TYR CD2 HD2  sing N N 404 
TYR CE1 CZ   doub Y N 405 
TYR CE1 HE1  sing N N 406 
TYR CE2 CZ   sing Y N 407 
TYR CE2 HE2  sing N N 408 
TYR CZ  OH   sing N N 409 
TYR OH  HH   sing N N 410 
TYR OXT HXT  sing N N 411 
VAL N   CA   sing N N 412 
VAL N   H    sing N N 413 
VAL N   H2   sing N N 414 
VAL CA  C    sing N N 415 
VAL CA  CB   sing N N 416 
VAL CA  HA   sing N N 417 
VAL C   O    doub N N 418 
VAL C   OXT  sing N N 419 
VAL CB  CG1  sing N N 420 
VAL CB  CG2  sing N N 421 
VAL CB  HB   sing N N 422 
VAL CG1 HG11 sing N N 423 
VAL CG1 HG12 sing N N 424 
VAL CG1 HG13 sing N N 425 
VAL CG2 HG21 sing N N 426 
VAL CG2 HG22 sing N N 427 
VAL CG2 HG23 sing N N 428 
VAL OXT HXT  sing N N 429 
# 
_pdbx_audit_support.funding_organization   'Bill & Melinda Gates Foundation' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           INV-004923 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
6 NAG 1 n 
6 NAG 2 n 
6 BMA 3 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8GF2 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9CPU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009072 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009072 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004341 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR A 1 1   ? 17.542  31.587  -31.657 1.00 73.32  ? 333 THR A N   1 
ATOM   2    C CA  . THR A 1 1   ? 17.670  32.354  -32.891 1.00 75.61  ? 333 THR A CA  1 
ATOM   3    C C   . THR A 1 1   ? 17.537  31.452  -34.115 1.00 72.05  ? 333 THR A C   1 
ATOM   4    O O   . THR A 1 1   ? 17.290  31.927  -35.223 1.00 71.16  ? 333 THR A O   1 
ATOM   5    C CB  . THR A 1 1   ? 19.018  33.097  -32.958 1.00 73.17  ? 333 THR A CB  1 
ATOM   6    O OG1 . THR A 1 1   ? 20.089  32.146  -32.990 1.00 90.45  ? 333 THR A OG1 1 
ATOM   7    C CG2 . THR A 1 1   ? 19.188  34.002  -31.748 1.00 71.52  ? 333 THR A CG2 1 
ATOM   8    N N   . ASN A 1 2   ? 17.701  30.149  -33.904 1.00 63.86  ? 334 ASN A N   1 
ATOM   9    C CA  . ASN A 1 2   ? 17.642  29.163  -34.974 1.00 63.94  ? 334 ASN A CA  1 
ATOM   10   C C   . ASN A 1 2   ? 16.623  28.087  -34.630 1.00 60.89  ? 334 ASN A C   1 
ATOM   11   O O   . ASN A 1 2   ? 16.560  27.620  -33.490 1.00 61.56  ? 334 ASN A O   1 
ATOM   12   C CB  . ASN A 1 2   ? 19.019  28.532  -35.218 1.00 62.47  ? 334 ASN A CB  1 
ATOM   13   C CG  . ASN A 1 2   ? 19.774  28.268  -33.930 1.00 77.19  ? 334 ASN A CG  1 
ATOM   14   O OD1 . ASN A 1 2   ? 19.616  28.991  -32.945 1.00 68.71  ? 334 ASN A OD1 1 
ATOM   15   N ND2 . ASN A 1 2   ? 20.603  27.231  -33.931 1.00 71.57  ? 334 ASN A ND2 1 
ATOM   16   N N   . LEU A 1 3   ? 15.828  27.699  -35.625 1.00 55.99  ? 335 LEU A N   1 
ATOM   17   C CA  . LEU A 1 3   ? 14.788  26.700  -35.418 1.00 46.13  ? 335 LEU A CA  1 
ATOM   18   C C   . LEU A 1 3   ? 15.395  25.320  -35.191 1.00 57.19  ? 335 LEU A C   1 
ATOM   19   O O   . LEU A 1 3   ? 16.371  24.938  -35.842 1.00 58.79  ? 335 LEU A O   1 
ATOM   20   C CB  . LEU A 1 3   ? 13.848  26.661  -36.624 1.00 41.08  ? 335 LEU A CB  1 
ATOM   21   C CG  . LEU A 1 3   ? 12.650  25.710  -36.550 1.00 51.15  ? 335 LEU A CG  1 
ATOM   22   C CD1 . LEU A 1 3   ? 11.495  26.351  -35.792 1.00 30.79  ? 335 LEU A CD1 1 
ATOM   23   C CD2 . LEU A 1 3   ? 12.215  25.269  -37.941 1.00 49.28  ? 335 LEU A CD2 1 
ATOM   24   N N   . CYS A 1 4   ? 14.811  24.572  -34.258 1.00 49.62  ? 336 CYS A N   1 
ATOM   25   C CA  . CYS A 1 4   ? 15.251  23.203  -34.030 1.00 38.14  ? 336 CYS A CA  1 
ATOM   26   C C   . CYS A 1 4   ? 14.846  22.322  -35.211 1.00 38.86  ? 336 CYS A C   1 
ATOM   27   O O   . CYS A 1 4   ? 13.715  22.414  -35.698 1.00 41.25  ? 336 CYS A O   1 
ATOM   28   C CB  . CYS A 1 4   ? 14.665  22.652  -32.732 1.00 42.74  ? 336 CYS A CB  1 
ATOM   29   S SG  . CYS A 1 4   ? 15.289  23.454  -31.234 1.00 66.92  ? 336 CYS A SG  1 
ATOM   30   N N   . PRO A 1 5   ? 15.742  21.457  -35.688 1.00 42.64  ? 337 PRO A N   1 
ATOM   31   C CA  . PRO A 1 5   ? 15.505  20.710  -36.938 1.00 42.31  ? 337 PRO A CA  1 
ATOM   32   C C   . PRO A 1 5   ? 14.592  19.501  -36.752 1.00 35.85  ? 337 PRO A C   1 
ATOM   33   O O   . PRO A 1 5   ? 14.973  18.352  -36.997 1.00 37.64  ? 337 PRO A O   1 
ATOM   34   C CB  . PRO A 1 5   ? 16.928  20.313  -37.348 1.00 43.42  ? 337 PRO A CB  1 
ATOM   35   C CG  . PRO A 1 5   ? 17.637  20.133  -36.050 1.00 43.01  ? 337 PRO A CG  1 
ATOM   36   C CD  . PRO A 1 5   ? 17.072  21.176  -35.119 1.00 36.68  ? 337 PRO A CD  1 
ATOM   37   N N   . PHE A 1 6   ? 13.355  19.759  -36.321 1.00 41.21  ? 338 PHE A N   1 
ATOM   38   C CA  . PHE A 1 6   ? 12.375  18.682  -36.224 1.00 31.97  ? 338 PHE A CA  1 
ATOM   39   C C   . PHE A 1 6   ? 11.920  18.208  -37.598 1.00 36.99  ? 338 PHE A C   1 
ATOM   40   O O   . PHE A 1 6   ? 11.606  17.024  -37.770 1.00 29.44  ? 338 PHE A O   1 
ATOM   41   C CB  . PHE A 1 6   ? 11.175  19.133  -35.392 1.00 41.91  ? 338 PHE A CB  1 
ATOM   42   C CG  . PHE A 1 6   ? 11.397  19.037  -33.911 1.00 46.33  ? 338 PHE A CG  1 
ATOM   43   C CD1 . PHE A 1 6   ? 12.165  18.014  -33.379 1.00 46.09  ? 338 PHE A CD1 1 
ATOM   44   C CD2 . PHE A 1 6   ? 10.841  19.969  -33.052 1.00 45.36  ? 338 PHE A CD2 1 
ATOM   45   C CE1 . PHE A 1 6   ? 12.373  17.920  -32.015 1.00 36.75  ? 338 PHE A CE1 1 
ATOM   46   C CE2 . PHE A 1 6   ? 11.046  19.883  -31.688 1.00 52.13  ? 338 PHE A CE2 1 
ATOM   47   C CZ  . PHE A 1 6   ? 11.812  18.856  -31.169 1.00 45.09  ? 338 PHE A CZ  1 
ATOM   48   N N   . GLY A 1 7   ? 11.876  19.110  -38.582 1.00 28.90  ? 339 GLY A N   1 
ATOM   49   C CA  . GLY A 1 7   ? 11.440  18.724  -39.914 1.00 30.44  ? 339 GLY A CA  1 
ATOM   50   C C   . GLY A 1 7   ? 12.346  17.701  -40.568 1.00 32.24  ? 339 GLY A C   1 
ATOM   51   O O   . GLY A 1 7   ? 11.875  16.835  -41.311 1.00 37.97  ? 339 GLY A O   1 
ATOM   52   N N   . GLU A 1 8   ? 13.653  17.785  -40.307 1.00 35.39  ? 340 GLU A N   1 
ATOM   53   C CA  . GLU A 1 8   ? 14.586  16.810  -40.861 1.00 37.04  ? 340 GLU A CA  1 
ATOM   54   C C   . GLU A 1 8   ? 14.307  15.405  -40.342 1.00 35.48  ? 340 GLU A C   1 
ATOM   55   O O   . GLU A 1 8   ? 14.585  14.421  -41.037 1.00 37.73  ? 340 GLU A O   1 
ATOM   56   C CB  . GLU A 1 8   ? 16.021  17.219  -40.532 1.00 40.03  ? 340 GLU A CB  1 
ATOM   57   C CG  . GLU A 1 8   ? 16.377  18.634  -40.955 1.00 54.20  ? 340 GLU A CG  1 
ATOM   58   C CD  . GLU A 1 8   ? 17.722  19.078  -40.417 1.00 66.43  ? 340 GLU A CD  1 
ATOM   59   O OE1 . GLU A 1 8   ? 18.368  18.278  -39.708 1.00 59.75  ? 340 GLU A OE1 1 
ATOM   60   O OE2 . GLU A 1 8   ? 18.129  20.226  -40.697 1.00 62.35  ? 340 GLU A OE2 1 
ATOM   61   N N   . VAL A 1 9   ? 13.765  15.291  -39.134 1.00 36.60  ? 341 VAL A N   1 
ATOM   62   C CA  . VAL A 1 9   ? 13.493  13.990  -38.531 1.00 33.44  ? 341 VAL A CA  1 
ATOM   63   C C   . VAL A 1 9   ? 12.134  13.451  -38.955 1.00 30.87  ? 341 VAL A C   1 
ATOM   64   O O   . VAL A 1 9   ? 12.026  12.322  -39.443 1.00 26.67  ? 341 VAL A O   1 
ATOM   65   C CB  . VAL A 1 9   ? 13.599  14.092  -36.994 1.00 33.35  ? 341 VAL A CB  1 
ATOM   66   C CG1 . VAL A 1 9   ? 13.239  12.763  -36.350 1.00 29.98  ? 341 VAL A CG1 1 
ATOM   67   C CG2 . VAL A 1 9   ? 14.995  14.533  -36.586 1.00 30.87  ? 341 VAL A CG2 1 
ATOM   68   N N   . PHE A 1 10  ? 11.077  14.247  -38.775 1.00 34.72  ? 342 PHE A N   1 
ATOM   69   C CA  . PHE A 1 10  ? 9.727   13.757  -39.034 1.00 30.00  ? 342 PHE A CA  1 
ATOM   70   C C   . PHE A 1 10  ? 9.472   13.562  -40.524 1.00 31.09  ? 342 PHE A C   1 
ATOM   71   O O   . PHE A 1 10  ? 8.768   12.625  -40.920 1.00 28.79  ? 342 PHE A O   1 
ATOM   72   C CB  . PHE A 1 10  ? 8.698   14.716  -38.438 1.00 22.73  ? 342 PHE A CB  1 
ATOM   73   C CG  . PHE A 1 10  ? 8.587   14.633  -36.943 1.00 25.98  ? 342 PHE A CG  1 
ATOM   74   C CD1 . PHE A 1 10  ? 9.391   15.416  -36.131 1.00 24.33  ? 342 PHE A CD1 1 
ATOM   75   C CD2 . PHE A 1 10  ? 7.678   13.773  -36.351 1.00 26.14  ? 342 PHE A CD2 1 
ATOM   76   C CE1 . PHE A 1 10  ? 9.290   15.341  -34.754 1.00 27.95  ? 342 PHE A CE1 1 
ATOM   77   C CE2 . PHE A 1 10  ? 7.572   13.693  -34.976 1.00 20.83  ? 342 PHE A CE2 1 
ATOM   78   C CZ  . PHE A 1 10  ? 8.378   14.479  -34.176 1.00 30.01  ? 342 PHE A CZ  1 
ATOM   79   N N   . ASN A 1 11  ? 10.027  14.432  -41.363 1.00 38.79  ? 343 ASN A N   1 
ATOM   80   C CA  . ASN A 1 11  ? 9.759   14.407  -42.794 1.00 42.46  ? 343 ASN A CA  1 
ATOM   81   C C   . ASN A 1 11  ? 10.879  13.760  -43.599 1.00 36.17  ? 343 ASN A C   1 
ATOM   82   O O   . ASN A 1 11  ? 10.898  13.893  -44.827 1.00 31.76  ? 343 ASN A O   1 
ATOM   83   C CB  . ASN A 1 11  ? 9.491   15.827  -43.300 1.00 38.15  ? 343 ASN A CB  1 
ATOM   84   C CG  . ASN A 1 11  ? 8.088   16.304  -42.972 1.00 34.47  ? 343 ASN A CG  1 
ATOM   85   O OD1 . ASN A 1 11  ? 7.144   15.515  -42.956 1.00 40.37  ? 343 ASN A OD1 1 
ATOM   86   N ND2 . ASN A 1 11  ? 7.943   17.599  -42.709 1.00 39.55  ? 343 ASN A ND2 1 
ATOM   87   N N   . ALA A 1 12  ? 11.802  13.061  -42.940 1.00 32.84  ? 344 ALA A N   1 
ATOM   88   C CA  . ALA A 1 12  ? 12.908  12.421  -43.642 1.00 33.05  ? 344 ALA A CA  1 
ATOM   89   C C   . ALA A 1 12  ? 12.395  11.413  -44.664 1.00 32.05  ? 344 ALA A C   1 
ATOM   90   O O   . ALA A 1 12  ? 11.450  10.663  -44.405 1.00 36.35  ? 344 ALA A O   1 
ATOM   91   C CB  . ALA A 1 12  ? 13.837  11.729  -42.645 1.00 32.71  ? 344 ALA A CB  1 
ATOM   92   N N   . THR A 1 13  ? 13.030  11.404  -45.838 1.00 37.74  ? 345 THR A N   1 
ATOM   93   C CA  . THR A 1 13  ? 12.598  10.515  -46.912 1.00 39.08  ? 345 THR A CA  1 
ATOM   94   C C   . THR A 1 13  ? 12.782  9.052   -46.529 1.00 38.61  ? 345 THR A C   1 
ATOM   95   O O   . THR A 1 13  ? 11.927  8.210   -46.826 1.00 32.14  ? 345 THR A O   1 
ATOM   96   C CB  . THR A 1 13  ? 13.367  10.833  -48.195 1.00 43.93  ? 345 THR A CB  1 
ATOM   97   O OG1 . THR A 1 13  ? 13.352  12.249  -48.424 1.00 38.77  ? 345 THR A OG1 1 
ATOM   98   C CG2 . THR A 1 13  ? 12.732  10.127  -49.384 1.00 18.15  ? 345 THR A CG2 1 
ATOM   99   N N   . ARG A 1 14  ? 13.892  8.731   -45.870 1.00 43.74  ? 346 ARG A N   1 
ATOM   100  C CA  . ARG A 1 14  ? 14.206  7.372   -45.455 1.00 35.90  ? 346 ARG A CA  1 
ATOM   101  C C   . ARG A 1 14  ? 14.299  7.306   -43.938 1.00 35.92  ? 346 ARG A C   1 
ATOM   102  O O   . ARG A 1 14  ? 14.887  8.187   -43.303 1.00 41.18  ? 346 ARG A O   1 
ATOM   103  C CB  . ARG A 1 14  ? 15.526  6.897   -46.075 1.00 42.20  ? 346 ARG A CB  1 
ATOM   104  C CG  . ARG A 1 14  ? 16.003  5.543   -45.570 1.00 58.44  ? 346 ARG A CG  1 
ATOM   105  C CD  . ARG A 1 14  ? 17.513  5.528   -45.378 1.00 72.73  ? 346 ARG A CD  1 
ATOM   106  N NE  . ARG A 1 14  ? 17.934  6.381   -44.272 1.00 67.63  ? 346 ARG A NE  1 
ATOM   107  C CZ  . ARG A 1 14  ? 18.234  5.940   -43.057 1.00 45.61  ? 346 ARG A CZ  1 
ATOM   108  N NH1 . ARG A 1 14  ? 18.184  4.653   -42.756 1.00 43.66  ? 346 ARG A NH1 1 
ATOM   109  N NH2 . ARG A 1 14  ? 18.598  6.813   -42.121 1.00 32.63  ? 346 ARG A NH2 1 
ATOM   110  N N   . PHE A 1 15  ? 13.714  6.260   -43.362 1.00 37.01  ? 347 PHE A N   1 
ATOM   111  C CA  . PHE A 1 15  ? 13.808  5.985   -41.937 1.00 27.59  ? 347 PHE A CA  1 
ATOM   112  C C   . PHE A 1 15  ? 14.690  4.765   -41.705 1.00 25.25  ? 347 PHE A C   1 
ATOM   113  O O   . PHE A 1 15  ? 14.805  3.887   -42.565 1.00 21.79  ? 347 PHE A O   1 
ATOM   114  C CB  . PHE A 1 15  ? 12.423  5.755   -41.325 1.00 30.26  ? 347 PHE A CB  1 
ATOM   115  C CG  . PHE A 1 15  ? 11.794  6.996   -40.760 1.00 25.76  ? 347 PHE A CG  1 
ATOM   116  C CD1 . PHE A 1 15  ? 11.693  8.146   -41.523 1.00 30.77  ? 347 PHE A CD1 1 
ATOM   117  C CD2 . PHE A 1 15  ? 11.290  7.007   -39.469 1.00 24.29  ? 347 PHE A CD2 1 
ATOM   118  C CE1 . PHE A 1 15  ? 11.111  9.289   -41.007 1.00 31.99  ? 347 PHE A CE1 1 
ATOM   119  C CE2 . PHE A 1 15  ? 10.705  8.147   -38.947 1.00 23.91  ? 347 PHE A CE2 1 
ATOM   120  C CZ  . PHE A 1 15  ? 10.616  9.289   -39.717 1.00 31.37  ? 347 PHE A CZ  1 
ATOM   121  N N   . ALA A 1 16  ? 15.316  4.721   -40.533 1.00 25.76  ? 348 ALA A N   1 
ATOM   122  C CA  . ALA A 1 16  ? 16.236  3.644   -40.207 1.00 20.54  ? 348 ALA A CA  1 
ATOM   123  C C   . ALA A 1 16  ? 15.481  2.406   -39.729 1.00 20.06  ? 348 ALA A C   1 
ATOM   124  O O   . ALA A 1 16  ? 14.343  2.480   -39.259 1.00 22.89  ? 348 ALA A O   1 
ATOM   125  C CB  . ALA A 1 16  ? 17.230  4.094   -39.136 1.00 22.93  ? 348 ALA A CB  1 
ATOM   126  N N   . SER A 1 17  ? 16.129  1.253   -39.872 1.00 17.71  ? 349 SER A N   1 
ATOM   127  C CA  . SER A 1 17  ? 15.604  0.029   -39.289 1.00 21.58  ? 349 SER A CA  1 
ATOM   128  C C   . SER A 1 17  ? 15.658  0.113   -37.767 1.00 25.86  ? 349 SER A C   1 
ATOM   129  O O   . SER A 1 17  ? 16.541  0.752   -37.190 1.00 19.72  ? 349 SER A O   1 
ATOM   130  C CB  . SER A 1 17  ? 16.388  -1.186  -39.783 1.00 20.42  ? 349 SER A CB  1 
ATOM   131  O OG  . SER A 1 17  ? 16.136  -1.429  -41.156 1.00 36.28  ? 349 SER A OG  1 
ATOM   132  N N   . VAL A 1 18  ? 14.694  -0.544  -37.117 1.00 19.92  ? 350 VAL A N   1 
ATOM   133  C CA  . VAL A 1 18  ? 14.524  -0.379  -35.675 1.00 20.67  ? 350 VAL A CA  1 
ATOM   134  C C   . VAL A 1 18  ? 15.739  -0.893  -34.911 1.00 21.33  ? 350 VAL A C   1 
ATOM   135  O O   . VAL A 1 18  ? 16.107  -0.333  -33.870 1.00 21.86  ? 350 VAL A O   1 
ATOM   136  C CB  . VAL A 1 18  ? 13.220  -1.057  -35.210 1.00 21.23  ? 350 VAL A CB  1 
ATOM   137  C CG1 . VAL A 1 18  ? 13.240  -2.548  -35.516 1.00 16.72  ? 350 VAL A CG1 1 
ATOM   138  C CG2 . VAL A 1 18  ? 12.985  -0.803  -33.728 1.00 9.81   ? 350 VAL A CG2 1 
ATOM   139  N N   . TYR A 1 19  ? 16.383  -1.956  -35.401 1.00 21.38  ? 351 TYR A N   1 
ATOM   140  C CA  . TYR A 1 19  ? 17.584  -2.450  -34.734 1.00 26.26  ? 351 TYR A CA  1 
ATOM   141  C C   . TYR A 1 19  ? 18.719  -1.435  -34.805 1.00 23.74  ? 351 TYR A C   1 
ATOM   142  O O   . TYR A 1 19  ? 19.596  -1.427  -33.934 1.00 31.30  ? 351 TYR A O   1 
ATOM   143  C CB  . TYR A 1 19  ? 18.021  -3.785  -35.341 1.00 23.41  ? 351 TYR A CB  1 
ATOM   144  C CG  . TYR A 1 19  ? 18.970  -3.662  -36.515 1.00 30.15  ? 351 TYR A CG  1 
ATOM   145  C CD1 . TYR A 1 19  ? 18.494  -3.416  -37.796 1.00 29.54  ? 351 TYR A CD1 1 
ATOM   146  C CD2 . TYR A 1 19  ? 20.343  -3.803  -36.341 1.00 28.34  ? 351 TYR A CD2 1 
ATOM   147  C CE1 . TYR A 1 19  ? 19.358  -3.306  -38.870 1.00 33.33  ? 351 TYR A CE1 1 
ATOM   148  C CE2 . TYR A 1 19  ? 21.213  -3.694  -37.408 1.00 32.83  ? 351 TYR A CE2 1 
ATOM   149  C CZ  . TYR A 1 19  ? 20.715  -3.446  -38.670 1.00 35.00  ? 351 TYR A CZ  1 
ATOM   150  O OH  . TYR A 1 19  ? 21.578  -3.337  -39.737 1.00 33.02  ? 351 TYR A OH  1 
ATOM   151  N N   . ALA A 1 20  ? 18.715  -0.576  -35.824 1.00 26.03  ? 352 ALA A N   1 
ATOM   152  C CA  . ALA A 1 20  ? 19.744  0.443   -35.996 1.00 29.41  ? 352 ALA A CA  1 
ATOM   153  C C   . ALA A 1 20  ? 19.114  1.829   -35.974 1.00 22.73  ? 352 ALA A C   1 
ATOM   154  O O   . ALA A 1 20  ? 19.389  2.659   -36.847 1.00 25.21  ? 352 ALA A O   1 
ATOM   155  C CB  . ALA A 1 20  ? 20.511  0.219   -37.301 1.00 20.92  ? 352 ALA A CB  1 
ATOM   156  N N   . TRP A 1 21  ? 18.259  2.076   -34.983 1.00 20.83  ? 353 TRP A N   1 
ATOM   157  C CA  . TRP A 1 21  ? 17.462  3.295   -34.943 1.00 21.67  ? 353 TRP A CA  1 
ATOM   158  C C   . TRP A 1 21  ? 18.339  4.542   -34.922 1.00 23.04  ? 353 TRP A C   1 
ATOM   159  O O   . TRP A 1 21  ? 19.364  4.594   -34.238 1.00 24.88  ? 353 TRP A O   1 
ATOM   160  C CB  . TRP A 1 21  ? 16.539  3.280   -33.721 1.00 22.31  ? 353 TRP A CB  1 
ATOM   161  C CG  . TRP A 1 21  ? 17.213  2.873   -32.438 1.00 19.77  ? 353 TRP A CG  1 
ATOM   162  C CD1 . TRP A 1 21  ? 17.443  1.600   -32.001 1.00 24.33  ? 353 TRP A CD1 1 
ATOM   163  C CD2 . TRP A 1 21  ? 17.728  3.743   -31.421 1.00 17.67  ? 353 TRP A CD2 1 
ATOM   164  N NE1 . TRP A 1 21  ? 18.075  1.623   -30.782 1.00 17.78  ? 353 TRP A NE1 1 
ATOM   165  C CE2 . TRP A 1 21  ? 18.261  2.926   -30.403 1.00 24.69  ? 353 TRP A CE2 1 
ATOM   166  C CE3 . TRP A 1 21  ? 17.792  5.132   -31.274 1.00 20.41  ? 353 TRP A CE3 1 
ATOM   167  C CZ2 . TRP A 1 21  ? 18.850  3.452   -29.254 1.00 26.61  ? 353 TRP A CZ2 1 
ATOM   168  C CZ3 . TRP A 1 21  ? 18.378  5.652   -30.132 1.00 27.71  ? 353 TRP A CZ3 1 
ATOM   169  C CH2 . TRP A 1 21  ? 18.899  4.813   -29.138 1.00 25.39  ? 353 TRP A CH2 1 
ATOM   170  N N   . ASN A 1 22  ? 17.926  5.547   -35.690 1.00 24.10  ? 354 ASN A N   1 
ATOM   171  C CA  . ASN A 1 22  ? 18.617  6.827   -35.726 1.00 25.86  ? 354 ASN A CA  1 
ATOM   172  C C   . ASN A 1 22  ? 18.326  7.637   -34.469 1.00 27.23  ? 354 ASN A C   1 
ATOM   173  O O   . ASN A 1 22  ? 17.285  7.480   -33.827 1.00 23.71  ? 354 ASN A O   1 
ATOM   174  C CB  . ASN A 1 22  ? 18.200  7.633   -36.958 1.00 28.32  ? 354 ASN A CB  1 
ATOM   175  C CG  . ASN A 1 22  ? 19.009  7.282   -38.190 1.00 35.62  ? 354 ASN A CG  1 
ATOM   176  O OD1 . ASN A 1 22  ? 19.719  6.278   -38.217 1.00 41.19  ? 354 ASN A OD1 1 
ATOM   177  N ND2 . ASN A 1 22  ? 18.906  8.114   -39.220 1.00 49.14  ? 354 ASN A ND2 1 
ATOM   178  N N   . ARG A 1 23  ? 19.267  8.512   -34.122 1.00 24.52  ? 355 ARG A N   1 
ATOM   179  C CA  . ARG A 1 23  ? 19.083  9.467   -33.039 1.00 22.99  ? 355 ARG A CA  1 
ATOM   180  C C   . ARG A 1 23  ? 19.593  10.826  -33.491 1.00 37.63  ? 355 ARG A C   1 
ATOM   181  O O   . ARG A 1 23  ? 20.712  10.933  -34.001 1.00 46.36  ? 355 ARG A O   1 
ATOM   182  C CB  . ARG A 1 23  ? 19.811  9.026   -31.763 1.00 30.07  ? 355 ARG A CB  1 
ATOM   183  C CG  . ARG A 1 23  ? 20.039  10.160  -30.774 1.00 32.63  ? 355 ARG A CG  1 
ATOM   184  C CD  . ARG A 1 23  ? 20.309  9.652   -29.369 1.00 24.12  ? 355 ARG A CD  1 
ATOM   185  N NE  . ARG A 1 23  ? 19.112  9.094   -28.752 1.00 33.86  ? 355 ARG A NE  1 
ATOM   186  C CZ  . ARG A 1 23  ? 18.987  8.843   -27.456 1.00 27.77  ? 355 ARG A CZ  1 
ATOM   187  N NH1 . ARG A 1 23  ? 19.967  9.100   -26.605 1.00 29.38  ? 355 ARG A NH1 1 
ATOM   188  N NH2 . ARG A 1 23  ? 17.849  8.325   -27.002 1.00 24.19  ? 355 ARG A NH2 1 
ATOM   189  N N   . LYS A 1 24  ? 18.772  11.854  -33.303 1.00 34.04  ? 356 LYS A N   1 
ATOM   190  C CA  . LYS A 1 24  ? 19.115  13.222  -33.667 1.00 27.55  ? 356 LYS A CA  1 
ATOM   191  C C   . LYS A 1 24  ? 19.288  14.035  -32.390 1.00 30.07  ? 356 LYS A C   1 
ATOM   192  O O   . LYS A 1 24  ? 18.340  14.180  -31.611 1.00 31.97  ? 356 LYS A O   1 
ATOM   193  C CB  . LYS A 1 24  ? 18.035  13.834  -34.560 1.00 31.78  ? 356 LYS A CB  1 
ATOM   194  C CG  . LYS A 1 24  ? 18.346  15.233  -35.064 1.00 38.02  ? 356 LYS A CG  1 
ATOM   195  C CD  . LYS A 1 24  ? 19.530  15.225  -36.014 1.00 46.20  ? 356 LYS A CD  1 
ATOM   196  C CE  . LYS A 1 24  ? 19.958  16.639  -36.365 1.00 52.89  ? 356 LYS A CE  1 
ATOM   197  N NZ  . LYS A 1 24  ? 21.418  16.708  -36.646 1.00 41.48  ? 356 LYS A NZ  1 
ATOM   198  N N   . ARG A 1 25  ? 20.492  14.561  -32.178 1.00 38.52  ? 357 ARG A N   1 
ATOM   199  C CA  . ARG A 1 25  ? 20.761  15.391  -31.011 1.00 41.97  ? 357 ARG A CA  1 
ATOM   200  C C   . ARG A 1 25  ? 20.297  16.815  -31.292 1.00 35.61  ? 357 ARG A C   1 
ATOM   201  O O   . ARG A 1 25  ? 20.748  17.442  -32.256 1.00 42.50  ? 357 ARG A O   1 
ATOM   202  C CB  . ARG A 1 25  ? 22.246  15.370  -30.657 1.00 38.91  ? 357 ARG A CB  1 
ATOM   203  C CG  . ARG A 1 25  ? 22.607  16.251  -29.465 1.00 44.86  ? 357 ARG A CG  1 
ATOM   204  C CD  . ARG A 1 25  ? 24.106  16.258  -29.198 1.00 54.91  ? 357 ARG A CD  1 
ATOM   205  N NE  . ARG A 1 25  ? 24.452  17.067  -28.034 1.00 53.96  ? 357 ARG A NE  1 
ATOM   206  C CZ  . ARG A 1 25  ? 24.866  18.325  -28.090 1.00 69.52  ? 357 ARG A CZ  1 
ATOM   207  N NH1 . ARG A 1 25  ? 25.012  18.956  -29.244 1.00 68.42  ? 357 ARG A NH1 1 
ATOM   208  N NH2 . ARG A 1 25  ? 25.142  18.968  -26.958 1.00 69.53  ? 357 ARG A NH2 1 
ATOM   209  N N   . ILE A 1 26  ? 19.399  17.322  -30.453 1.00 43.47  ? 358 ILE A N   1 
ATOM   210  C CA  . ILE A 1 26  ? 18.842  18.661  -30.598 1.00 31.21  ? 358 ILE A CA  1 
ATOM   211  C C   . ILE A 1 26  ? 19.449  19.536  -29.511 1.00 44.37  ? 358 ILE A C   1 
ATOM   212  O O   . ILE A 1 26  ? 19.294  19.251  -28.317 1.00 45.07  ? 358 ILE A O   1 
ATOM   213  C CB  . ILE A 1 26  ? 17.308  18.646  -30.511 1.00 40.79  ? 358 ILE A CB  1 
ATOM   214  C CG1 . ILE A 1 26  ? 16.722  17.680  -31.545 1.00 36.71  ? 358 ILE A CG1 1 
ATOM   215  C CG2 . ILE A 1 26  ? 16.746  20.039  -30.704 1.00 38.66  ? 358 ILE A CG2 1 
ATOM   216  C CD1 . ILE A 1 26  ? 17.063  18.033  -32.975 1.00 40.58  ? 358 ILE A CD1 1 
ATOM   217  N N   . SER A 1 27  ? 20.143  20.597  -29.920 1.00 46.81  ? 359 SER A N   1 
ATOM   218  C CA  . SER A 1 27  ? 20.791  21.488  -28.971 1.00 48.19  ? 359 SER A CA  1 
ATOM   219  C C   . SER A 1 27  ? 20.934  22.872  -29.586 1.00 47.42  ? 359 SER A C   1 
ATOM   220  O O   . SER A 1 27  ? 21.066  23.016  -30.805 1.00 54.26  ? 359 SER A O   1 
ATOM   221  C CB  . SER A 1 27  ? 22.165  20.956  -28.545 1.00 56.26  ? 359 SER A CB  1 
ATOM   222  O OG  . SER A 1 27  ? 23.051  20.888  -29.649 1.00 58.72  ? 359 SER A OG  1 
ATOM   223  N N   . ASN A 1 28  ? 20.908  23.885  -28.721 1.00 58.43  ? 360 ASN A N   1 
ATOM   224  C CA  . ASN A 1 28  ? 21.153  25.279  -29.088 1.00 57.87  ? 360 ASN A CA  1 
ATOM   225  C C   . ASN A 1 28  ? 20.238  25.728  -30.229 1.00 59.92  ? 360 ASN A C   1 
ATOM   226  O O   . ASN A 1 28  ? 20.684  26.107  -31.314 1.00 59.71  ? 360 ASN A O   1 
ATOM   227  C CB  . ASN A 1 28  ? 22.625  25.495  -29.445 1.00 54.41  ? 360 ASN A CB  1 
ATOM   228  C CG  . ASN A 1 28  ? 23.097  26.901  -29.136 1.00 82.76  ? 360 ASN A CG  1 
ATOM   229  O OD1 . ASN A 1 28  ? 22.647  27.519  -28.171 1.00 78.79  ? 360 ASN A OD1 1 
ATOM   230  N ND2 . ASN A 1 28  ? 24.003  27.416  -29.957 1.00 81.81  ? 360 ASN A ND2 1 
ATOM   231  N N   . CYS A 1 29  ? 18.936  25.678  -29.961 1.00 60.83  ? 361 CYS A N   1 
ATOM   232  C CA  . CYS A 1 29  ? 17.936  26.099  -30.932 1.00 52.01  ? 361 CYS A CA  1 
ATOM   233  C C   . CYS A 1 29  ? 16.628  26.364  -30.201 1.00 52.14  ? 361 CYS A C   1 
ATOM   234  O O   . CYS A 1 29  ? 16.447  25.971  -29.046 1.00 60.16  ? 361 CYS A O   1 
ATOM   235  C CB  . CYS A 1 29  ? 17.751  25.049  -32.034 1.00 54.57  ? 361 CYS A CB  1 
ATOM   236  S SG  . CYS A 1 29  ? 17.313  23.405  -31.432 1.00 62.77  ? 361 CYS A SG  1 
ATOM   237  N N   . VAL A 1 30  ? 15.715  27.043  -30.892 1.00 48.67  ? 362 VAL A N   1 
ATOM   238  C CA  . VAL A 1 30  ? 14.369  27.295  -30.389 1.00 58.37  ? 362 VAL A CA  1 
ATOM   239  C C   . VAL A 1 30  ? 13.410  26.347  -31.095 1.00 57.89  ? 362 VAL A C   1 
ATOM   240  O O   . VAL A 1 30  ? 13.373  26.290  -32.331 1.00 46.56  ? 362 VAL A O   1 
ATOM   241  C CB  . VAL A 1 30  ? 13.955  28.764  -30.585 1.00 38.81  ? 362 VAL A CB  1 
ATOM   242  C CG1 . VAL A 1 30  ? 14.275  29.239  -31.994 1.00 53.06  ? 362 VAL A CG1 1 
ATOM   243  C CG2 . VAL A 1 30  ? 12.474  28.945  -30.280 1.00 45.00  ? 362 VAL A CG2 1 
ATOM   244  N N   . ALA A 1 31  ? 12.649  25.588  -30.314 1.00 56.93  ? 363 ALA A N   1 
ATOM   245  C CA  . ALA A 1 31  ? 11.763  24.562  -30.844 1.00 55.55  ? 363 ALA A CA  1 
ATOM   246  C C   . ALA A 1 31  ? 10.321  25.041  -30.776 1.00 50.85  ? 363 ALA A C   1 
ATOM   247  O O   . ALA A 1 31  ? 9.889   25.591  -29.757 1.00 50.97  ? 363 ALA A O   1 
ATOM   248  C CB  . ALA A 1 31  ? 11.923  23.251  -30.070 1.00 49.52  ? 363 ALA A CB  1 
ATOM   249  N N   . ASP A 1 32  ? 9.585   24.839  -31.863 1.00 43.28  ? 364 ASP A N   1 
ATOM   250  C CA  . ASP A 1 32  ? 8.164   25.164  -31.934 1.00 51.40  ? 364 ASP A CA  1 
ATOM   251  C C   . ASP A 1 32  ? 7.415   23.836  -32.004 1.00 49.82  ? 364 ASP A C   1 
ATOM   252  O O   . ASP A 1 32  ? 7.186   23.290  -33.084 1.00 51.73  ? 364 ASP A O   1 
ATOM   253  C CB  . ASP A 1 32  ? 7.855   26.059  -33.134 1.00 59.22  ? 364 ASP A CB  1 
ATOM   254  C CG  . ASP A 1 32  ? 6.578   26.861  -32.952 1.00 68.78  ? 364 ASP A CG  1 
ATOM   255  O OD1 . ASP A 1 32  ? 5.634   26.351  -32.311 1.00 55.29  ? 364 ASP A OD1 1 
ATOM   256  O OD2 . ASP A 1 32  ? 6.521   28.007  -33.449 1.00 75.30  ? 364 ASP A OD2 1 
ATOM   257  N N   . TYR A 1 33  ? 7.037   23.316  -30.835 1.00 48.88  ? 365 TYR A N   1 
ATOM   258  C CA  . TYR A 1 33  ? 6.373   22.020  -30.762 1.00 44.56  ? 365 TYR A CA  1 
ATOM   259  C C   . TYR A 1 33  ? 4.936   22.061  -31.260 1.00 44.33  ? 365 TYR A C   1 
ATOM   260  O O   . TYR A 1 33  ? 4.327   20.997  -31.418 1.00 34.47  ? 365 TYR A O   1 
ATOM   261  C CB  . TYR A 1 33  ? 6.406   21.497  -29.326 1.00 43.47  ? 365 TYR A CB  1 
ATOM   262  C CG  . TYR A 1 33  ? 7.799   21.354  -28.756 1.00 42.14  ? 365 TYR A CG  1 
ATOM   263  C CD1 . TYR A 1 33  ? 8.552   20.211  -28.991 1.00 33.92  ? 365 TYR A CD1 1 
ATOM   264  C CD2 . TYR A 1 33  ? 8.361   22.361  -27.982 1.00 40.99  ? 365 TYR A CD2 1 
ATOM   265  C CE1 . TYR A 1 33  ? 9.825   20.075  -28.471 1.00 29.20  ? 365 TYR A CE1 1 
ATOM   266  C CE2 . TYR A 1 33  ? 9.633   22.233  -27.457 1.00 41.04  ? 365 TYR A CE2 1 
ATOM   267  C CZ  . TYR A 1 33  ? 10.360  21.088  -27.705 1.00 37.80  ? 365 TYR A CZ  1 
ATOM   268  O OH  . TYR A 1 33  ? 11.627  20.956  -27.185 1.00 40.55  ? 365 TYR A OH  1 
ATOM   269  N N   . SER A 1 34  ? 4.383   23.251  -31.508 1.00 43.02  ? 366 SER A N   1 
ATOM   270  C CA  . SER A 1 34  ? 2.995   23.350  -31.949 1.00 32.88  ? 366 SER A CA  1 
ATOM   271  C C   . SER A 1 34  ? 2.786   22.713  -33.316 1.00 35.71  ? 366 SER A C   1 
ATOM   272  O O   . SER A 1 34  ? 1.703   22.186  -33.594 1.00 31.82  ? 366 SER A O   1 
ATOM   273  C CB  . SER A 1 34  ? 2.555   24.813  -31.968 1.00 42.39  ? 366 SER A CB  1 
ATOM   274  O OG  . SER A 1 34  ? 3.460   25.603  -32.719 1.00 52.44  ? 366 SER A OG  1 
ATOM   275  N N   . VAL A 1 35  ? 3.804   22.742  -34.181 1.00 30.97  ? 367 VAL A N   1 
ATOM   276  C CA  . VAL A 1 35  ? 3.690   22.103  -35.487 1.00 39.82  ? 367 VAL A CA  1 
ATOM   277  C C   . VAL A 1 35  ? 3.588   20.590  -35.389 1.00 36.82  ? 367 VAL A C   1 
ATOM   278  O O   . VAL A 1 35  ? 3.290   19.932  -36.393 1.00 40.61  ? 367 VAL A O   1 
ATOM   279  C CB  . VAL A 1 35  ? 4.878   22.478  -36.398 1.00 39.68  ? 367 VAL A CB  1 
ATOM   280  C CG1 . VAL A 1 35  ? 4.907   23.979  -36.646 1.00 36.24  ? 367 VAL A CG1 1 
ATOM   281  C CG2 . VAL A 1 35  ? 6.189   22.001  -35.794 1.00 34.90  ? 367 VAL A CG2 1 
ATOM   282  N N   . LEU A 1 36  ? 3.830   20.020  -34.208 1.00 41.01  ? 368 LEU A N   1 
ATOM   283  C CA  . LEU A 1 36  ? 3.717   18.578  -34.016 1.00 33.06  ? 368 LEU A CA  1 
ATOM   284  C C   . LEU A 1 36  ? 2.331   18.180  -33.510 1.00 32.88  ? 368 LEU A C   1 
ATOM   285  O O   . LEU A 1 36  ? 1.634   17.391  -34.155 1.00 30.53  ? 368 LEU A O   1 
ATOM   286  C CB  . LEU A 1 36  ? 4.805   18.087  -33.055 1.00 39.07  ? 368 LEU A CB  1 
ATOM   287  C CG  . LEU A 1 36  ? 6.245   18.176  -33.565 1.00 37.34  ? 368 LEU A CG  1 
ATOM   288  C CD1 . LEU A 1 36  ? 7.214   17.598  -32.545 1.00 31.81  ? 368 LEU A CD1 1 
ATOM   289  C CD2 . LEU A 1 36  ? 6.384   17.467  -34.904 1.00 33.18  ? 368 LEU A CD2 1 
ATOM   290  N N   . TYR A 1 37  ? 1.916   18.719  -32.359 1.00 27.34  ? 369 TYR A N   1 
ATOM   291  C CA  . TYR A 1 37  ? 0.669   18.259  -31.757 1.00 37.34  ? 369 TYR A CA  1 
ATOM   292  C C   . TYR A 1 37  ? -0.575  18.819  -32.439 1.00 35.96  ? 369 TYR A C   1 
ATOM   293  O O   . TYR A 1 37  ? -1.647  18.218  -32.319 1.00 45.49  ? 369 TYR A O   1 
ATOM   294  C CB  . TYR A 1 37  ? 0.635   18.574  -30.254 1.00 27.75  ? 369 TYR A CB  1 
ATOM   295  C CG  . TYR A 1 37  ? 0.827   20.022  -29.849 1.00 29.30  ? 369 TYR A CG  1 
ATOM   296  C CD1 . TYR A 1 37  ? -0.193  20.954  -30.004 1.00 34.11  ? 369 TYR A CD1 1 
ATOM   297  C CD2 . TYR A 1 37  ? 2.012   20.443  -29.258 1.00 25.84  ? 369 TYR A CD2 1 
ATOM   298  C CE1 . TYR A 1 37  ? -0.024  22.272  -29.614 1.00 25.34  ? 369 TYR A CE1 1 
ATOM   299  C CE2 . TYR A 1 37  ? 2.189   21.758  -28.863 1.00 29.07  ? 369 TYR A CE2 1 
ATOM   300  C CZ  . TYR A 1 37  ? 1.168   22.667  -29.043 1.00 40.04  ? 369 TYR A CZ  1 
ATOM   301  O OH  . TYR A 1 37  ? 1.341   23.976  -28.652 1.00 44.65  ? 369 TYR A OH  1 
ATOM   302  N N   . ASN A 1 38  ? -0.465  19.933  -33.160 1.00 40.31  ? 370 ASN A N   1 
ATOM   303  C CA  . ASN A 1 38  ? -1.604  20.440  -33.917 1.00 41.94  ? 370 ASN A CA  1 
ATOM   304  C C   . ASN A 1 38  ? -1.763  19.755  -35.267 1.00 24.63  ? 370 ASN A C   1 
ATOM   305  O O   . ASN A 1 38  ? -2.717  20.060  -35.991 1.00 35.91  ? 370 ASN A O   1 
ATOM   306  C CB  . ASN A 1 38  ? -1.486  21.954  -34.118 1.00 23.68  ? 370 ASN A CB  1 
ATOM   307  C CG  . ASN A 1 38  ? -1.856  22.738  -32.874 1.00 31.24  ? 370 ASN A CG  1 
ATOM   308  O OD1 . ASN A 1 38  ? -2.642  22.277  -32.047 1.00 45.05  ? 370 ASN A OD1 1 
ATOM   309  N ND2 . ASN A 1 38  ? -1.293  23.933  -32.738 1.00 35.51  ? 370 ASN A ND2 1 
ATOM   310  N N   . SER A 1 39  ? -0.859  18.845  -35.619 1.00 31.09  ? 371 SER A N   1 
ATOM   311  C CA  . SER A 1 39  ? -0.941  18.136  -36.884 1.00 34.10  ? 371 SER A CA  1 
ATOM   312  C C   . SER A 1 39  ? -2.097  17.137  -36.867 1.00 27.41  ? 371 SER A C   1 
ATOM   313  O O   . SER A 1 39  ? -2.669  16.815  -35.822 1.00 40.97  ? 371 SER A O   1 
ATOM   314  C CB  . SER A 1 39  ? 0.375   17.415  -37.177 1.00 25.54  ? 371 SER A CB  1 
ATOM   315  O OG  . SER A 1 39  ? 0.254   16.577  -38.313 1.00 32.18  ? 371 SER A OG  1 
ATOM   316  N N   . ALA A 1 40  ? -2.439  16.645  -38.057 1.00 27.91  ? 372 ALA A N   1 
ATOM   317  C CA  . ALA A 1 40  ? -3.496  15.660  -38.222 1.00 23.57  ? 372 ALA A CA  1 
ATOM   318  C C   . ALA A 1 40  ? -3.012  14.369  -38.865 1.00 29.83  ? 372 ALA A C   1 
ATOM   319  O O   . ALA A 1 40  ? -3.814  13.443  -39.040 1.00 34.89  ? 372 ALA A O   1 
ATOM   320  C CB  . ALA A 1 40  ? -4.645  16.245  -39.054 1.00 17.01  ? 372 ALA A CB  1 
ATOM   321  N N   . SER A 1 41  ? -1.730  14.277  -39.221 1.00 30.10  ? 373 SER A N   1 
ATOM   322  C CA  . SER A 1 41  ? -1.194  13.095  -39.883 1.00 40.52  ? 373 SER A CA  1 
ATOM   323  C C   . SER A 1 41  ? -0.808  11.985  -38.915 1.00 36.40  ? 373 SER A C   1 
ATOM   324  O O   . SER A 1 41  ? -0.534  10.866  -39.362 1.00 40.11  ? 373 SER A O   1 
ATOM   325  C CB  . SER A 1 41  ? 0.025   13.478  -40.728 1.00 38.55  ? 373 SER A CB  1 
ATOM   326  O OG  . SER A 1 41  ? 1.011   14.118  -39.935 1.00 41.55  ? 373 SER A OG  1 
ATOM   327  N N   . PHE A 1 42  ? -0.787  12.258  -37.613 1.00 32.79  ? 374 PHE A N   1 
ATOM   328  C CA  . PHE A 1 42  ? -0.343  11.285  -36.624 1.00 32.08  ? 374 PHE A CA  1 
ATOM   329  C C   . PHE A 1 42  ? -1.514  10.431  -36.157 1.00 31.97  ? 374 PHE A C   1 
ATOM   330  O O   . PHE A 1 42  ? -2.596  10.951  -35.866 1.00 36.31  ? 374 PHE A O   1 
ATOM   331  C CB  . PHE A 1 42  ? 0.301   11.991  -35.431 1.00 24.09  ? 374 PHE A CB  1 
ATOM   332  C CG  . PHE A 1 42  ? 1.520   12.792  -35.786 1.00 29.70  ? 374 PHE A CG  1 
ATOM   333  C CD1 . PHE A 1 42  ? 2.431   12.317  -36.715 1.00 28.82  ? 374 PHE A CD1 1 
ATOM   334  C CD2 . PHE A 1 42  ? 1.750   14.024  -35.197 1.00 27.14  ? 374 PHE A CD2 1 
ATOM   335  C CE1 . PHE A 1 42  ? 3.554   13.053  -37.044 1.00 27.04  ? 374 PHE A CE1 1 
ATOM   336  C CE2 . PHE A 1 42  ? 2.870   14.766  -35.522 1.00 27.44  ? 374 PHE A CE2 1 
ATOM   337  C CZ  . PHE A 1 42  ? 3.773   14.279  -36.447 1.00 32.64  ? 374 PHE A CZ  1 
ATOM   338  N N   . SER A 1 43  ? -1.292  9.118   -36.090 1.00 26.62  ? 375 SER A N   1 
ATOM   339  C CA  . SER A 1 43  ? -2.279  8.200   -35.540 1.00 22.72  ? 375 SER A CA  1 
ATOM   340  C C   . SER A 1 43  ? -2.044  7.897   -34.067 1.00 29.36  ? 375 SER A C   1 
ATOM   341  O O   . SER A 1 43  ? -2.993  7.530   -33.365 1.00 31.61  ? 375 SER A O   1 
ATOM   342  C CB  . SER A 1 43  ? -2.286  6.890   -36.335 1.00 28.51  ? 375 SER A CB  1 
ATOM   343  O OG  . SER A 1 43  ? -1.011  6.272   -36.320 1.00 31.12  ? 375 SER A OG  1 
ATOM   344  N N   . THR A 1 44  ? -0.810  8.043   -33.588 1.00 27.43  ? 376 THR A N   1 
ATOM   345  C CA  . THR A 1 44  ? -0.465  7.809   -32.191 1.00 27.07  ? 376 THR A CA  1 
ATOM   346  C C   . THR A 1 44  ? 0.412   8.952   -31.706 1.00 26.02  ? 376 THR A C   1 
ATOM   347  O O   . THR A 1 44  ? 1.468   9.219   -32.289 1.00 24.91  ? 376 THR A O   1 
ATOM   348  C CB  . THR A 1 44  ? 0.257   6.469   -32.013 1.00 32.30  ? 376 THR A CB  1 
ATOM   349  O OG1 . THR A 1 44  ? -0.687  5.396   -32.123 1.00 40.63  ? 376 THR A OG1 1 
ATOM   350  C CG2 . THR A 1 44  ? 0.945   6.405   -30.658 1.00 25.19  ? 376 THR A CG2 1 
ATOM   351  N N   . PHE A 1 45  ? -0.031  9.631   -30.648 1.00 22.33  ? 377 PHE A N   1 
ATOM   352  C CA  . PHE A 1 45  ? 0.743   10.695  -30.003 1.00 26.34  ? 377 PHE A CA  1 
ATOM   353  C C   . PHE A 1 45  ? 0.636   10.452  -28.498 1.00 25.61  ? 377 PHE A C   1 
ATOM   354  O O   . PHE A 1 45  ? -0.230  11.021  -27.828 1.00 25.68  ? 377 PHE A O   1 
ATOM   355  C CB  . PHE A 1 45  ? 0.218   12.069  -30.398 1.00 28.81  ? 377 PHE A CB  1 
ATOM   356  C CG  . PHE A 1 45  ? 1.254   13.156  -30.354 1.00 27.75  ? 377 PHE A CG  1 
ATOM   357  C CD1 . PHE A 1 45  ? 1.871   13.500  -29.163 1.00 32.37  ? 377 PHE A CD1 1 
ATOM   358  C CD2 . PHE A 1 45  ? 1.595   13.848  -31.504 1.00 32.21  ? 377 PHE A CD2 1 
ATOM   359  C CE1 . PHE A 1 45  ? 2.817   14.507  -29.123 1.00 27.87  ? 377 PHE A CE1 1 
ATOM   360  C CE2 . PHE A 1 45  ? 2.539   14.856  -31.469 1.00 26.01  ? 377 PHE A CE2 1 
ATOM   361  C CZ  . PHE A 1 45  ? 3.151   15.185  -30.277 1.00 33.04  ? 377 PHE A CZ  1 
ATOM   362  N N   . LYS A 1 46  ? 1.524   9.614   -27.972 1.00 25.25  ? 378 LYS A N   1 
ATOM   363  C CA  . LYS A 1 46  ? 1.488   9.204   -26.573 1.00 24.65  ? 378 LYS A CA  1 
ATOM   364  C C   . LYS A 1 46  ? 2.680   9.808   -25.846 1.00 32.45  ? 378 LYS A C   1 
ATOM   365  O O   . LYS A 1 46  ? 3.832   9.529   -26.196 1.00 38.67  ? 378 LYS A O   1 
ATOM   366  C CB  . LYS A 1 46  ? 1.490   7.680   -26.446 1.00 19.71  ? 378 LYS A CB  1 
ATOM   367  C CG  . LYS A 1 46  ? 0.298   7.010   -27.108 1.00 25.22  ? 378 LYS A CG  1 
ATOM   368  C CD  . LYS A 1 46  ? -0.295  5.919   -26.231 1.00 29.80  ? 378 LYS A CD  1 
ATOM   369  C CE  . LYS A 1 46  ? 0.599   4.697   -26.167 1.00 38.94  ? 378 LYS A CE  1 
ATOM   370  N NZ  . LYS A 1 46  ? -0.002  3.626   -25.323 1.00 31.70  ? 378 LYS A NZ  1 
ATOM   371  N N   . CYS A 1 47  ? 2.401   10.626  -24.835 1.00 17.52  ? 379 CYS A N   1 
ATOM   372  C CA  . CYS A 1 47  ? 3.429   11.298  -24.057 1.00 24.09  ? 379 CYS A CA  1 
ATOM   373  C C   . CYS A 1 47  ? 3.321   10.888  -22.597 1.00 30.51  ? 379 CYS A C   1 
ATOM   374  O O   . CYS A 1 47  ? 2.219   10.681  -22.079 1.00 28.75  ? 379 CYS A O   1 
ATOM   375  C CB  . CYS A 1 47  ? 3.312   12.814  -24.185 1.00 27.07  ? 379 CYS A CB  1 
ATOM   376  S SG  . CYS A 1 47  ? 3.445   13.409  -25.877 1.00 38.96  ? 379 CYS A SG  1 
ATOM   377  N N   . TYR A 1 48  ? 4.472   10.775  -21.939 1.00 27.09  ? 380 TYR A N   1 
ATOM   378  C CA  . TYR A 1 48  ? 4.555   10.282  -20.571 1.00 27.45  ? 380 TYR A CA  1 
ATOM   379  C C   . TYR A 1 48  ? 5.331   11.287  -19.736 1.00 25.36  ? 380 TYR A C   1 
ATOM   380  O O   . TYR A 1 48  ? 6.476   11.614  -20.063 1.00 27.25  ? 380 TYR A O   1 
ATOM   381  C CB  . TYR A 1 48  ? 5.229   8.907   -20.527 1.00 20.90  ? 380 TYR A CB  1 
ATOM   382  C CG  . TYR A 1 48  ? 4.582   7.879   -21.430 1.00 21.61  ? 380 TYR A CG  1 
ATOM   383  C CD1 . TYR A 1 48  ? 4.861   7.845   -22.791 1.00 18.90  ? 380 TYR A CD1 1 
ATOM   384  C CD2 . TYR A 1 48  ? 3.697   6.940   -20.920 1.00 19.99  ? 380 TYR A CD2 1 
ATOM   385  C CE1 . TYR A 1 48  ? 4.270   6.909   -23.619 1.00 17.42  ? 380 TYR A CE1 1 
ATOM   386  C CE2 . TYR A 1 48  ? 3.103   5.999   -21.740 1.00 22.87  ? 380 TYR A CE2 1 
ATOM   387  C CZ  . TYR A 1 48  ? 3.394   5.988   -23.087 1.00 22.59  ? 380 TYR A CZ  1 
ATOM   388  O OH  . TYR A 1 48  ? 2.805   5.051   -23.905 1.00 22.24  ? 380 TYR A OH  1 
ATOM   389  N N   . GLY A 1 49  ? 4.708   11.781  -18.669 1.00 24.36  ? 381 GLY A N   1 
ATOM   390  C CA  . GLY A 1 49  ? 5.374   12.668  -17.740 1.00 21.83  ? 381 GLY A CA  1 
ATOM   391  C C   . GLY A 1 49  ? 5.499   14.107  -18.186 1.00 25.36  ? 381 GLY A C   1 
ATOM   392  O O   . GLY A 1 49  ? 6.073   14.917  -17.446 1.00 38.18  ? 381 GLY A O   1 
ATOM   393  N N   . VAL A 1 50  ? 4.988   14.458  -19.366 1.00 23.14  ? 382 VAL A N   1 
ATOM   394  C CA  . VAL A 1 50  ? 5.056   15.831  -19.855 1.00 33.88  ? 382 VAL A CA  1 
ATOM   395  C C   . VAL A 1 50  ? 3.950   16.021  -20.881 1.00 27.84  ? 382 VAL A C   1 
ATOM   396  O O   . VAL A 1 50  ? 3.554   15.078  -21.572 1.00 26.80  ? 382 VAL A O   1 
ATOM   397  C CB  . VAL A 1 50  ? 6.455   16.152  -20.443 1.00 30.09  ? 382 VAL A CB  1 
ATOM   398  C CG1 . VAL A 1 50  ? 6.631   15.512  -21.814 1.00 34.72  ? 382 VAL A CG1 1 
ATOM   399  C CG2 . VAL A 1 50  ? 6.678   17.658  -20.508 1.00 32.40  ? 382 VAL A CG2 1 
ATOM   400  N N   . SER A 1 51  ? 3.434   17.252  -20.965 1.00 31.74  ? 383 SER A N   1 
ATOM   401  C CA  . SER A 1 51  ? 2.405   17.605  -21.935 1.00 27.72  ? 383 SER A CA  1 
ATOM   402  C C   . SER A 1 51  ? 3.035   18.302  -23.128 1.00 29.56  ? 383 SER A C   1 
ATOM   403  O O   . SER A 1 51  ? 3.811   19.250  -22.938 1.00 36.00  ? 383 SER A O   1 
ATOM   404  C CB  . SER A 1 51  ? 1.357   18.515  -21.300 1.00 32.91  ? 383 SER A CB  1 
ATOM   405  O OG  . SER A 1 51  ? 0.722   17.880  -20.205 1.00 32.53  ? 383 SER A OG  1 
ATOM   406  N N   . PRO A 1 52  ? 2.749   17.864  -24.359 1.00 33.09  ? 384 PRO A N   1 
ATOM   407  C CA  . PRO A 1 52  ? 3.282   18.587  -25.527 1.00 32.96  ? 384 PRO A CA  1 
ATOM   408  C C   . PRO A 1 52  ? 2.846   20.037  -25.569 1.00 35.67  ? 384 PRO A C   1 
ATOM   409  O O   . PRO A 1 52  ? 3.620   20.907  -25.986 1.00 39.60  ? 384 PRO A O   1 
ATOM   410  C CB  . PRO A 1 52  ? 2.721   17.802  -26.721 1.00 39.09  ? 384 PRO A CB  1 
ATOM   411  C CG  . PRO A 1 52  ? 2.274   16.509  -26.175 1.00 35.14  ? 384 PRO A CG  1 
ATOM   412  C CD  . PRO A 1 52  ? 1.911   16.719  -24.744 1.00 30.47  ? 384 PRO A CD  1 
ATOM   413  N N   . THR A 1 53  ? 1.615   20.319  -25.137 1.00 36.89  ? 385 THR A N   1 
ATOM   414  C CA  . THR A 1 53  ? 1.126   21.690  -25.098 1.00 35.76  ? 385 THR A CA  1 
ATOM   415  C C   . THR A 1 53  ? 1.898   22.549  -24.105 1.00 39.02  ? 385 THR A C   1 
ATOM   416  O O   . THR A 1 53  ? 1.822   23.779  -24.180 1.00 51.17  ? 385 THR A O   1 
ATOM   417  C CB  . THR A 1 53  ? -0.362  21.700  -24.750 1.00 42.22  ? 385 THR A CB  1 
ATOM   418  O OG1 . THR A 1 53  ? -0.533  21.312  -23.381 1.00 43.98  ? 385 THR A OG1 1 
ATOM   419  C CG2 . THR A 1 53  ? -1.116  20.721  -25.638 1.00 30.12  ? 385 THR A CG2 1 
ATOM   420  N N   . LYS A 1 54  ? 2.632   21.931  -23.181 1.00 38.34  ? 386 LYS A N   1 
ATOM   421  C CA  . LYS A 1 54  ? 3.445   22.641  -22.204 1.00 42.11  ? 386 LYS A CA  1 
ATOM   422  C C   . LYS A 1 54  ? 4.930   22.615  -22.544 1.00 45.43  ? 386 LYS A C   1 
ATOM   423  O O   . LYS A 1 54  ? 5.752   23.018  -21.714 1.00 52.37  ? 386 LYS A O   1 
ATOM   424  C CB  . LYS A 1 54  ? 3.221   22.053  -20.808 1.00 46.78  ? 386 LYS A CB  1 
ATOM   425  C CG  . LYS A 1 54  ? 1.784   22.135  -20.325 1.00 40.34  ? 386 LYS A CG  1 
ATOM   426  C CD  . LYS A 1 54  ? 1.430   23.561  -19.944 1.00 49.20  ? 386 LYS A CD  1 
ATOM   427  C CE  . LYS A 1 54  ? -0.074  23.763  -19.837 1.00 50.03  ? 386 LYS A CE  1 
ATOM   428  N NZ  . LYS A 1 54  ? -0.756  23.545  -21.145 1.00 48.30  ? 386 LYS A NZ  1 
ATOM   429  N N   . LEU A 1 55  ? 5.294   22.138  -23.735 1.00 43.20  ? 387 LEU A N   1 
ATOM   430  C CA  . LEU A 1 55  ? 6.691   22.093  -24.148 1.00 50.49  ? 387 LEU A CA  1 
ATOM   431  C C   . LEU A 1 55  ? 7.181   23.398  -24.761 1.00 58.10  ? 387 LEU A C   1 
ATOM   432  O O   . LEU A 1 55  ? 8.389   23.660  -24.737 1.00 63.12  ? 387 LEU A O   1 
ATOM   433  C CB  . LEU A 1 55  ? 6.910   20.954  -25.149 1.00 40.26  ? 387 LEU A CB  1 
ATOM   434  C CG  . LEU A 1 55  ? 6.900   19.534  -24.586 1.00 39.68  ? 387 LEU A CG  1 
ATOM   435  C CD1 . LEU A 1 55  ? 6.965   18.516  -25.711 1.00 36.29  ? 387 LEU A CD1 1 
ATOM   436  C CD2 . LEU A 1 55  ? 8.054   19.338  -23.613 1.00 41.12  ? 387 LEU A CD2 1 
ATOM   437  N N   . ASN A 1 56  ? 6.280   24.220  -25.304 1.00 57.91  ? 388 ASN A N   1 
ATOM   438  C CA  . ASN A 1 56  ? 6.679   25.481  -25.918 1.00 62.92  ? 388 ASN A CA  1 
ATOM   439  C C   . ASN A 1 56  ? 7.127   26.521  -24.901 1.00 64.31  ? 388 ASN A C   1 
ATOM   440  O O   . ASN A 1 56  ? 7.633   27.574  -25.304 1.00 74.16  ? 388 ASN A O   1 
ATOM   441  C CB  . ASN A 1 56  ? 5.534   26.046  -26.763 1.00 59.46  ? 388 ASN A CB  1 
ATOM   442  C CG  . ASN A 1 56  ? 5.457   25.412  -28.139 1.00 58.26  ? 388 ASN A CG  1 
ATOM   443  O OD1 . ASN A 1 56  ? 6.461   24.947  -28.678 1.00 53.13  ? 388 ASN A OD1 1 
ATOM   444  N ND2 . ASN A 1 56  ? 4.262   25.398  -28.719 1.00 60.02  ? 388 ASN A ND2 1 
ATOM   445  N N   . ASP A 1 57  ? 6.948   26.267  -23.607 1.00 56.24  ? 389 ASP A N   1 
ATOM   446  C CA  . ASP A 1 57  ? 7.374   27.182  -22.556 1.00 65.60  ? 389 ASP A CA  1 
ATOM   447  C C   . ASP A 1 57  ? 8.247   26.463  -21.535 1.00 55.23  ? 389 ASP A C   1 
ATOM   448  O O   . ASP A 1 57  ? 8.131   26.681  -20.326 1.00 52.78  ? 389 ASP A O   1 
ATOM   449  C CB  . ASP A 1 57  ? 6.171   27.838  -21.881 1.00 73.85  ? 389 ASP A CB  1 
ATOM   450  C CG  . ASP A 1 57  ? 5.011   26.880  -21.697 1.00 74.66  ? 389 ASP A CG  1 
ATOM   451  O OD1 . ASP A 1 57  ? 5.145   25.703  -22.087 1.00 79.80  ? 389 ASP A OD1 1 
ATOM   452  O OD2 . ASP A 1 57  ? 3.963   27.307  -21.167 1.00 64.62  ? 389 ASP A OD2 1 
ATOM   453  N N   . LEU A 1 58  ? 9.138   25.594  -22.011 1.00 62.79  ? 390 LEU A N   1 
ATOM   454  C CA  . LEU A 1 58  ? 10.076  24.891  -21.148 1.00 62.57  ? 390 LEU A CA  1 
ATOM   455  C C   . LEU A 1 58  ? 11.452  24.871  -21.798 1.00 67.45  ? 390 LEU A C   1 
ATOM   456  O O   . LEU A 1 58  ? 11.580  24.956  -23.022 1.00 66.76  ? 390 LEU A O   1 
ATOM   457  C CB  . LEU A 1 58  ? 9.622   23.455  -20.853 1.00 61.74  ? 390 LEU A CB  1 
ATOM   458  C CG  . LEU A 1 58  ? 9.156   23.178  -19.422 1.00 58.09  ? 390 LEU A CG  1 
ATOM   459  C CD1 . LEU A 1 58  ? 9.133   21.682  -19.148 1.00 57.29  ? 390 LEU A CD1 1 
ATOM   460  C CD2 . LEU A 1 58  ? 10.041  23.900  -18.416 1.00 53.41  ? 390 LEU A CD2 1 
ATOM   461  N N   . CYS A 1 59  ? 12.480  24.750  -20.961 1.00 61.16  ? 391 CYS A N   1 
ATOM   462  C CA  . CYS A 1 59  ? 13.867  24.707  -21.402 1.00 58.11  ? 391 CYS A CA  1 
ATOM   463  C C   . CYS A 1 59  ? 14.502  23.385  -20.996 1.00 56.07  ? 391 CYS A C   1 
ATOM   464  O O   . CYS A 1 59  ? 14.277  22.891  -19.886 1.00 61.98  ? 391 CYS A O   1 
ATOM   465  C CB  . CYS A 1 59  ? 14.677  25.862  -20.808 1.00 65.17  ? 391 CYS A CB  1 
ATOM   466  S SG  . CYS A 1 59  ? 14.320  27.501  -21.478 1.00 101.80 ? 391 CYS A SG  1 
ATOM   467  N N   . PHE A 1 60  ? 15.300  22.820  -21.898 1.00 59.22  ? 392 PHE A N   1 
ATOM   468  C CA  . PHE A 1 60  ? 16.028  21.587  -21.640 1.00 58.35  ? 392 PHE A CA  1 
ATOM   469  C C   . PHE A 1 60  ? 17.463  21.735  -22.122 1.00 64.37  ? 392 PHE A C   1 
ATOM   470  O O   . PHE A 1 60  ? 17.741  22.464  -23.077 1.00 58.25  ? 392 PHE A O   1 
ATOM   471  C CB  . PHE A 1 60  ? 15.375  20.383  -22.336 1.00 50.48  ? 392 PHE A CB  1 
ATOM   472  C CG  . PHE A 1 60  ? 13.896  20.275  -22.103 1.00 44.90  ? 392 PHE A CG  1 
ATOM   473  C CD1 . PHE A 1 60  ? 13.402  19.681  -20.954 1.00 47.98  ? 392 PHE A CD1 1 
ATOM   474  C CD2 . PHE A 1 60  ? 12.998  20.761  -23.039 1.00 52.50  ? 392 PHE A CD2 1 
ATOM   475  C CE1 . PHE A 1 60  ? 12.041  19.579  -20.741 1.00 53.22  ? 392 PHE A CE1 1 
ATOM   476  C CE2 . PHE A 1 60  ? 11.635  20.661  -22.832 1.00 58.06  ? 392 PHE A CE2 1 
ATOM   477  C CZ  . PHE A 1 60  ? 11.157  20.069  -21.681 1.00 63.62  ? 392 PHE A CZ  1 
ATOM   478  N N   . THR A 1 61  ? 18.378  21.039  -21.443 1.00 69.71  ? 393 THR A N   1 
ATOM   479  C CA  . THR A 1 61  ? 19.770  21.035  -21.881 1.00 61.93  ? 393 THR A CA  1 
ATOM   480  C C   . THR A 1 61  ? 19.922  20.344  -23.231 1.00 57.23  ? 393 THR A C   1 
ATOM   481  O O   . THR A 1 61  ? 20.664  20.820  -24.098 1.00 50.73  ? 393 THR A O   1 
ATOM   482  C CB  . THR A 1 61  ? 20.655  20.363  -20.832 1.00 77.11  ? 393 THR A CB  1 
ATOM   483  O OG1 . THR A 1 61  ? 19.999  19.194  -20.326 1.00 83.87  ? 393 THR A OG1 1 
ATOM   484  C CG2 . THR A 1 61  ? 20.941  21.319  -19.687 1.00 83.53  ? 393 THR A CG2 1 
ATOM   485  N N   . ASN A 1 62  ? 19.226  19.227  -23.430 1.00 57.22  ? 394 ASN A N   1 
ATOM   486  C CA  . ASN A 1 62  ? 19.277  18.505  -24.692 1.00 55.29  ? 394 ASN A CA  1 
ATOM   487  C C   . ASN A 1 62  ? 17.939  17.826  -24.942 1.00 51.88  ? 394 ASN A C   1 
ATOM   488  O O   . ASN A 1 62  ? 17.207  17.494  -24.006 1.00 52.85  ? 394 ASN A O   1 
ATOM   489  C CB  . ASN A 1 62  ? 20.402  17.462  -24.710 1.00 55.57  ? 394 ASN A CB  1 
ATOM   490  C CG  . ASN A 1 62  ? 21.748  18.057  -25.078 1.00 64.24  ? 394 ASN A CG  1 
ATOM   491  O OD1 . ASN A 1 62  ? 21.835  18.958  -25.913 1.00 65.49  ? 394 ASN A OD1 1 
ATOM   492  N ND2 . ASN A 1 62  ? 22.808  17.551  -24.458 1.00 64.18  ? 394 ASN A ND2 1 
ATOM   493  N N   . VAL A 1 63  ? 17.631  17.626  -26.221 1.00 36.93  ? 395 VAL A N   1 
ATOM   494  C CA  . VAL A 1 63  ? 16.455  16.883  -26.655 1.00 26.66  ? 395 VAL A CA  1 
ATOM   495  C C   . VAL A 1 63  ? 16.906  15.869  -27.695 1.00 35.80  ? 395 VAL A C   1 
ATOM   496  O O   . VAL A 1 63  ? 17.697  16.193  -28.587 1.00 37.33  ? 395 VAL A O   1 
ATOM   497  C CB  . VAL A 1 63  ? 15.363  17.812  -27.229 1.00 34.63  ? 395 VAL A CB  1 
ATOM   498  C CG1 . VAL A 1 63  ? 14.207  16.998  -27.792 1.00 25.88  ? 395 VAL A CG1 1 
ATOM   499  C CG2 . VAL A 1 63  ? 14.865  18.774  -26.162 1.00 37.72  ? 395 VAL A CG2 1 
ATOM   500  N N   . TYR A 1 64  ? 16.421  14.636  -27.573 1.00 28.03  ? 396 TYR A N   1 
ATOM   501  C CA  . TYR A 1 64  ? 16.776  13.564  -28.491 1.00 25.48  ? 396 TYR A CA  1 
ATOM   502  C C   . TYR A 1 64  ? 15.530  13.086  -29.219 1.00 32.41  ? 396 TYR A C   1 
ATOM   503  O O   . TYR A 1 64  ? 14.487  12.862  -28.596 1.00 35.44  ? 396 TYR A O   1 
ATOM   504  C CB  . TYR A 1 64  ? 17.442  12.400  -27.751 1.00 28.80  ? 396 TYR A CB  1 
ATOM   505  C CG  . TYR A 1 64  ? 18.691  12.799  -27.001 1.00 36.73  ? 396 TYR A CG  1 
ATOM   506  C CD1 . TYR A 1 64  ? 19.903  12.950  -27.662 1.00 38.72  ? 396 TYR A CD1 1 
ATOM   507  C CD2 . TYR A 1 64  ? 18.659  13.029  -25.631 1.00 34.97  ? 396 TYR A CD2 1 
ATOM   508  C CE1 . TYR A 1 64  ? 21.048  13.318  -26.981 1.00 34.64  ? 396 TYR A CE1 1 
ATOM   509  C CE2 . TYR A 1 64  ? 19.798  13.396  -24.941 1.00 36.16  ? 396 TYR A CE2 1 
ATOM   510  C CZ  . TYR A 1 64  ? 20.989  13.540  -25.621 1.00 43.73  ? 396 TYR A CZ  1 
ATOM   511  O OH  . TYR A 1 64  ? 22.125  13.906  -24.936 1.00 51.80  ? 396 TYR A OH  1 
ATOM   512  N N   . ALA A 1 65  ? 15.640  12.942  -30.538 1.00 24.19  ? 397 ALA A N   1 
ATOM   513  C CA  . ALA A 1 65  ? 14.566  12.424  -31.374 1.00 23.01  ? 397 ALA A CA  1 
ATOM   514  C C   . ALA A 1 65  ? 15.057  11.156  -32.056 1.00 25.62  ? 397 ALA A C   1 
ATOM   515  O O   . ALA A 1 65  ? 15.989  11.203  -32.865 1.00 23.80  ? 397 ALA A O   1 
ATOM   516  C CB  . ALA A 1 65  ? 14.121  13.459  -32.409 1.00 21.71  ? 397 ALA A CB  1 
ATOM   517  N N   . ASP A 1 66  ? 14.431  10.029  -31.729 1.00 24.80  ? 398 ASP A N   1 
ATOM   518  C CA  . ASP A 1 66  ? 14.781  8.735   -32.296 1.00 25.18  ? 398 ASP A CA  1 
ATOM   519  C C   . ASP A 1 66  ? 13.722  8.319   -33.306 1.00 19.52  ? 398 ASP A C   1 
ATOM   520  O O   . ASP A 1 66  ? 12.523  8.453   -33.049 1.00 30.91  ? 398 ASP A O   1 
ATOM   521  C CB  . ASP A 1 66  ? 14.908  7.673   -31.201 1.00 22.96  ? 398 ASP A CB  1 
ATOM   522  C CG  . ASP A 1 66  ? 15.887  8.072   -30.113 1.00 33.38  ? 398 ASP A CG  1 
ATOM   523  O OD1 . ASP A 1 66  ? 16.859  8.793   -30.423 1.00 33.43  ? 398 ASP A OD1 1 
ATOM   524  O OD2 . ASP A 1 66  ? 15.682  7.670   -28.948 1.00 28.93  ? 398 ASP A OD2 1 
ATOM   525  N N   . SER A 1 67  ? 14.167  7.813   -34.455 1.00 19.96  ? 399 SER A N   1 
ATOM   526  C CA  . SER A 1 67  ? 13.272  7.449   -35.544 1.00 22.45  ? 399 SER A CA  1 
ATOM   527  C C   . SER A 1 67  ? 13.591  6.049   -36.045 1.00 19.88  ? 399 SER A C   1 
ATOM   528  O O   . SER A 1 67  ? 14.759  5.652   -36.100 1.00 22.95  ? 399 SER A O   1 
ATOM   529  C CB  . SER A 1 67  ? 13.373  8.452   -36.700 1.00 28.06  ? 399 SER A CB  1 
ATOM   530  O OG  . SER A 1 67  ? 14.697  8.525   -37.198 1.00 25.46  ? 399 SER A OG  1 
ATOM   531  N N   . PHE A 1 68  ? 12.548  5.311   -36.415 1.00 18.72  ? 400 PHE A N   1 
ATOM   532  C CA  . PHE A 1 68  ? 12.677  3.959   -36.951 1.00 14.62  ? 400 PHE A CA  1 
ATOM   533  C C   . PHE A 1 68  ? 11.323  3.543   -37.519 1.00 13.06  ? 400 PHE A C   1 
ATOM   534  O O   . PHE A 1 68  ? 10.337  4.280   -37.427 1.00 14.98  ? 400 PHE A O   1 
ATOM   535  C CB  . PHE A 1 68  ? 13.168  2.974   -35.887 1.00 14.32  ? 400 PHE A CB  1 
ATOM   536  C CG  . PHE A 1 68  ? 12.409  3.047   -34.594 1.00 12.45  ? 400 PHE A CG  1 
ATOM   537  C CD1 . PHE A 1 68  ? 11.249  2.312   -34.413 1.00 17.48  ? 400 PHE A CD1 1 
ATOM   538  C CD2 . PHE A 1 68  ? 12.859  3.846   -33.556 1.00 11.59  ? 400 PHE A CD2 1 
ATOM   539  C CE1 . PHE A 1 68  ? 10.551  2.377   -33.222 1.00 24.43  ? 400 PHE A CE1 1 
ATOM   540  C CE2 . PHE A 1 68  ? 12.165  3.916   -32.364 1.00 15.64  ? 400 PHE A CE2 1 
ATOM   541  C CZ  . PHE A 1 68  ? 11.010  3.180   -32.196 1.00 13.63  ? 400 PHE A CZ  1 
ATOM   542  N N   . VAL A 1 69  ? 11.286  2.349   -38.110 1.00 16.57  ? 401 VAL A N   1 
ATOM   543  C CA  . VAL A 1 69  ? 10.086  1.802   -38.732 1.00 17.31  ? 401 VAL A CA  1 
ATOM   544  C C   . VAL A 1 69  ? 9.832   0.411   -38.168 1.00 21.53  ? 401 VAL A C   1 
ATOM   545  O O   . VAL A 1 69  ? 10.746  -0.419  -38.114 1.00 24.37  ? 401 VAL A O   1 
ATOM   546  C CB  . VAL A 1 69  ? 10.212  1.747   -40.267 1.00 21.96  ? 401 VAL A CB  1 
ATOM   547  C CG1 . VAL A 1 69  ? 9.174   0.807   -40.862 1.00 23.51  ? 401 VAL A CG1 1 
ATOM   548  C CG2 . VAL A 1 69  ? 10.060  3.135   -40.856 1.00 32.86  ? 401 VAL A CG2 1 
ATOM   549  N N   . ILE A 1 70  ? 8.592   0.159   -37.749 1.00 23.07  ? 402 ILE A N   1 
ATOM   550  C CA  . ILE A 1 70  ? 8.162   -1.126  -37.216 1.00 27.32  ? 402 ILE A CA  1 
ATOM   551  C C   . ILE A 1 70  ? 6.780   -1.446  -37.774 1.00 23.92  ? 402 ILE A C   1 
ATOM   552  O O   . ILE A 1 70  ? 6.169   -0.642  -38.483 1.00 23.21  ? 402 ILE A O   1 
ATOM   553  C CB  . ILE A 1 70  ? 8.136   -1.140  -35.673 1.00 28.98  ? 402 ILE A CB  1 
ATOM   554  C CG1 . ILE A 1 70  ? 7.353   0.065   -35.144 1.00 20.71  ? 402 ILE A CG1 1 
ATOM   555  C CG2 . ILE A 1 70  ? 9.546   -1.170  -35.108 1.00 21.58  ? 402 ILE A CG2 1 
ATOM   556  C CD1 . ILE A 1 70  ? 7.315   0.155   -33.637 1.00 19.13  ? 402 ILE A CD1 1 
ATOM   557  N N   . ARG A 1 71  ? 6.288   -2.638  -37.449 1.00 29.17  ? 403 ARG A N   1 
ATOM   558  C CA  . ARG A 1 71  ? 4.925   -3.012  -37.792 1.00 29.27  ? 403 ARG A CA  1 
ATOM   559  C C   . ARG A 1 71  ? 3.927   -2.229  -36.945 1.00 27.57  ? 403 ARG A C   1 
ATOM   560  O O   . ARG A 1 71  ? 4.263   -1.658  -35.904 1.00 27.63  ? 403 ARG A O   1 
ATOM   561  C CB  . ARG A 1 71  ? 4.705   -4.510  -37.587 1.00 28.68  ? 403 ARG A CB  1 
ATOM   562  C CG  . ARG A 1 71  ? 5.192   -5.384  -38.723 1.00 35.37  ? 403 ARG A CG  1 
ATOM   563  C CD  . ARG A 1 71  ? 4.959   -6.853  -38.410 1.00 35.29  ? 403 ARG A CD  1 
ATOM   564  N NE  . ARG A 1 71  ? 3.606   -7.098  -37.926 1.00 29.13  ? 403 ARG A NE  1 
ATOM   565  C CZ  . ARG A 1 71  ? 3.064   -8.300  -37.791 1.00 35.51  ? 403 ARG A CZ  1 
ATOM   566  N NH1 . ARG A 1 71  ? 3.728   -9.398  -38.111 1.00 31.59  ? 403 ARG A NH1 1 
ATOM   567  N NH2 . ARG A 1 71  ? 1.822   -8.403  -37.325 1.00 38.83  ? 403 ARG A NH2 1 
ATOM   568  N N   . GLY A 1 72  ? 2.676   -2.211  -37.409 1.00 34.20  ? 404 GLY A N   1 
ATOM   569  C CA  . GLY A 1 72  ? 1.625   -1.563  -36.642 1.00 31.74  ? 404 GLY A CA  1 
ATOM   570  C C   . GLY A 1 72  ? 1.341   -2.269  -35.331 1.00 26.89  ? 404 GLY A C   1 
ATOM   571  O O   . GLY A 1 72  ? 1.059   -1.624  -34.317 1.00 22.61  ? 404 GLY A O   1 
ATOM   572  N N   . ASP A 1 73  ? 1.409   -3.604  -35.330 1.00 29.06  ? 405 ASP A N   1 
ATOM   573  C CA  . ASP A 1 73  ? 1.179   -4.368  -34.110 1.00 31.75  ? 405 ASP A CA  1 
ATOM   574  C C   . ASP A 1 73  ? 2.225   -4.087  -33.039 1.00 32.89  ? 405 ASP A C   1 
ATOM   575  O O   . ASP A 1 73  ? 1.942   -4.273  -31.850 1.00 38.21  ? 405 ASP A O   1 
ATOM   576  C CB  . ASP A 1 73  ? 1.157   -5.868  -34.418 1.00 36.58  ? 405 ASP A CB  1 
ATOM   577  C CG  . ASP A 1 73  ? -0.071  -6.287  -35.202 1.00 57.88  ? 405 ASP A CG  1 
ATOM   578  O OD1 . ASP A 1 73  ? -1.101  -5.586  -35.118 1.00 58.66  ? 405 ASP A OD1 1 
ATOM   579  O OD2 . ASP A 1 73  ? -0.006  -7.324  -35.896 1.00 62.51  ? 405 ASP A OD2 1 
ATOM   580  N N   . GLU A 1 74  ? 3.419   -3.651  -33.428 1.00 31.72  ? 406 GLU A N   1 
ATOM   581  C CA  . GLU A 1 74  ? 4.520   -3.443  -32.497 1.00 22.60  ? 406 GLU A CA  1 
ATOM   582  C C   . GLU A 1 74  ? 4.605   -2.017  -31.970 1.00 25.84  ? 406 GLU A C   1 
ATOM   583  O O   . GLU A 1 74  ? 5.479   -1.731  -31.145 1.00 22.76  ? 406 GLU A O   1 
ATOM   584  C CB  . GLU A 1 74  ? 5.844   -3.824  -33.167 1.00 19.63  ? 406 GLU A CB  1 
ATOM   585  C CG  . GLU A 1 74  ? 5.905   -5.272  -33.624 1.00 18.94  ? 406 GLU A CG  1 
ATOM   586  C CD  . GLU A 1 74  ? 7.062   -5.541  -34.566 1.00 37.09  ? 406 GLU A CD  1 
ATOM   587  O OE1 . GLU A 1 74  ? 7.578   -4.574  -35.166 1.00 39.67  ? 406 GLU A OE1 1 
ATOM   588  O OE2 . GLU A 1 74  ? 7.458   -6.718  -34.703 1.00 35.33  ? 406 GLU A OE2 1 
ATOM   589  N N   . VAL A 1 75  ? 3.725   -1.119  -32.419 1.00 26.32  ? 407 VAL A N   1 
ATOM   590  C CA  . VAL A 1 75  ? 3.785   0.271   -31.971 1.00 24.99  ? 407 VAL A CA  1 
ATOM   591  C C   . VAL A 1 75  ? 3.509   0.370   -30.477 1.00 28.03  ? 407 VAL A C   1 
ATOM   592  O O   . VAL A 1 75  ? 4.092   1.213   -29.783 1.00 29.36  ? 407 VAL A O   1 
ATOM   593  C CB  . VAL A 1 75  ? 2.808   1.136   -32.791 1.00 26.48  ? 407 VAL A CB  1 
ATOM   594  C CG1 . VAL A 1 75  ? 2.836   2.580   -32.315 1.00 16.07  ? 407 VAL A CG1 1 
ATOM   595  C CG2 . VAL A 1 75  ? 3.150   1.057   -34.270 1.00 25.83  ? 407 VAL A CG2 1 
ATOM   596  N N   . ARG A 1 76  ? 2.628   -0.485  -29.955 1.00 26.49  ? 408 ARG A N   1 
ATOM   597  C CA  . ARG A 1 76  ? 2.327   -0.469  -28.529 1.00 24.68  ? 408 ARG A CA  1 
ATOM   598  C C   . ARG A 1 76  ? 3.517   -0.898  -27.678 1.00 27.13  ? 408 ARG A C   1 
ATOM   599  O O   . ARG A 1 76  ? 3.523   -0.634  -26.470 1.00 28.50  ? 408 ARG A O   1 
ATOM   600  C CB  . ARG A 1 76  ? 1.116   -1.360  -28.244 1.00 24.44  ? 408 ARG A CB  1 
ATOM   601  C CG  . ARG A 1 76  ? 1.286   -2.809  -28.671 1.00 32.58  ? 408 ARG A CG  1 
ATOM   602  C CD  . ARG A 1 76  ? -0.051  -3.450  -29.031 1.00 48.70  ? 408 ARG A CD  1 
ATOM   603  N NE  . ARG A 1 76  ? -1.102  -3.147  -28.066 1.00 60.40  ? 408 ARG A NE  1 
ATOM   604  C CZ  . ARG A 1 76  ? -2.144  -2.362  -28.311 1.00 56.71  ? 408 ARG A CZ  1 
ATOM   605  N NH1 . ARG A 1 76  ? -2.316  -1.790  -29.492 1.00 54.32  ? 408 ARG A NH1 1 
ATOM   606  N NH2 . ARG A 1 76  ? -3.037  -2.151  -27.349 1.00 54.26  ? 408 ARG A NH2 1 
ATOM   607  N N   . GLN A 1 77  ? 4.523   -1.541  -28.274 1.00 20.74  ? 409 GLN A N   1 
ATOM   608  C CA  . GLN A 1 77  ? 5.736   -1.897  -27.548 1.00 17.97  ? 409 GLN A CA  1 
ATOM   609  C C   . GLN A 1 77  ? 6.646   -0.705  -27.287 1.00 22.21  ? 409 GLN A C   1 
ATOM   610  O O   . GLN A 1 77  ? 7.556   -0.814  -26.458 1.00 25.21  ? 409 GLN A O   1 
ATOM   611  C CB  . GLN A 1 77  ? 6.522   -2.969  -28.307 1.00 14.17  ? 409 GLN A CB  1 
ATOM   612  C CG  . GLN A 1 77  ? 5.839   -4.323  -28.370 1.00 12.82  ? 409 GLN A CG  1 
ATOM   613  C CD  . GLN A 1 77  ? 6.732   -5.389  -28.969 1.00 19.53  ? 409 GLN A CD  1 
ATOM   614  O OE1 . GLN A 1 77  ? 7.931   -5.434  -28.696 1.00 22.40  ? 409 GLN A OE1 1 
ATOM   615  N NE2 . GLN A 1 77  ? 6.153   -6.249  -29.799 1.00 17.96  ? 409 GLN A NE2 1 
ATOM   616  N N   . ILE A 1 78  ? 6.437   0.417   -27.970 1.00 28.35  ? 410 ILE A N   1 
ATOM   617  C CA  . ILE A 1 78  ? 7.263   1.617   -27.750 1.00 25.69  ? 410 ILE A CA  1 
ATOM   618  C C   . ILE A 1 78  ? 6.557   2.420   -26.664 1.00 27.81  ? 410 ILE A C   1 
ATOM   619  O O   . ILE A 1 78  ? 5.825   3.381   -26.915 1.00 32.75  ? 410 ILE A O   1 
ATOM   620  C CB  . ILE A 1 78  ? 7.476   2.417   -29.039 1.00 21.15  ? 410 ILE A CB  1 
ATOM   621  C CG1 . ILE A 1 78  ? 7.820   1.478   -30.196 1.00 21.14  ? 410 ILE A CG1 1 
ATOM   622  C CG2 . ILE A 1 78  ? 8.582   3.442   -28.849 1.00 21.82  ? 410 ILE A CG2 1 
ATOM   623  C CD1 . ILE A 1 78  ? 9.074   0.660   -29.966 1.00 22.47  ? 410 ILE A CD1 1 
ATOM   624  N N   . ALA A 1 79  ? 6.804   2.026   -25.416 1.00 32.21  ? 411 ALA A N   1 
ATOM   625  C CA  . ALA A 1 79  ? 6.167   2.622   -24.248 1.00 28.97  ? 411 ALA A CA  1 
ATOM   626  C C   . ALA A 1 79  ? 6.897   2.159   -22.994 1.00 34.96  ? 411 ALA A C   1 
ATOM   627  O O   . ALA A 1 79  ? 7.527   1.093   -23.007 1.00 34.48  ? 411 ALA A O   1 
ATOM   628  C CB  . ALA A 1 79  ? 4.685   2.243   -24.184 1.00 22.71  ? 411 ALA A CB  1 
ATOM   629  N N   . PRO A 1 80  ? 6.853   2.924   -21.902 1.00 29.09  ? 412 PRO A N   1 
ATOM   630  C CA  . PRO A 1 80  ? 7.511   2.477   -20.669 1.00 30.08  ? 412 PRO A CA  1 
ATOM   631  C C   . PRO A 1 80  ? 6.905   1.183   -20.146 1.00 33.61  ? 412 PRO A C   1 
ATOM   632  O O   . PRO A 1 80  ? 5.695   0.960   -20.233 1.00 36.17  ? 412 PRO A O   1 
ATOM   633  C CB  . PRO A 1 80  ? 7.277   3.641   -19.699 1.00 29.58  ? 412 PRO A CB  1 
ATOM   634  C CG  . PRO A 1 80  ? 6.095   4.366   -20.253 1.00 26.62  ? 412 PRO A CG  1 
ATOM   635  C CD  . PRO A 1 80  ? 6.224   4.245   -21.739 1.00 29.69  ? 412 PRO A CD  1 
ATOM   636  N N   . GLY A 1 81  ? 7.765   0.328   -19.599 1.00 34.10  ? 413 GLY A N   1 
ATOM   637  C CA  . GLY A 1 81  ? 7.316   -0.922  -19.007 1.00 39.39  ? 413 GLY A CA  1 
ATOM   638  C C   . GLY A 1 81  ? 6.646   -1.867  -19.980 1.00 31.12  ? 413 GLY A C   1 
ATOM   639  O O   . GLY A 1 81  ? 5.639   -2.498  -19.634 1.00 37.73  ? 413 GLY A O   1 
ATOM   640  N N   . GLN A 1 82  ? 7.181   -1.983  -21.190 1.00 32.25  ? 414 GLN A N   1 
ATOM   641  C CA  . GLN A 1 82  ? 6.607   -2.849  -22.206 1.00 23.00  ? 414 GLN A CA  1 
ATOM   642  C C   . GLN A 1 82  ? 7.575   -3.976  -22.536 1.00 23.49  ? 414 GLN A C   1 
ATOM   643  O O   . GLN A 1 82  ? 8.775   -3.899  -22.260 1.00 34.04  ? 414 GLN A O   1 
ATOM   644  C CB  . GLN A 1 82  ? 6.250   -2.067  -23.474 1.00 35.47  ? 414 GLN A CB  1 
ATOM   645  C CG  . GLN A 1 82  ? 4.926   -2.492  -24.083 1.00 33.19  ? 414 GLN A CG  1 
ATOM   646  C CD  . GLN A 1 82  ? 3.766   -2.320  -23.121 1.00 42.90  ? 414 GLN A CD  1 
ATOM   647  O OE1 . GLN A 1 82  ? 3.698   -1.335  -22.383 1.00 46.01  ? 414 GLN A OE1 1 
ATOM   648  N NE2 . GLN A 1 82  ? 2.851   -3.282  -23.117 1.00 45.85  ? 414 GLN A NE2 1 
ATOM   649  N N   . THR A 1 83  ? 7.031   -5.031  -23.137 1.00 28.05  ? 415 THR A N   1 
ATOM   650  C CA  . THR A 1 83  ? 7.767   -6.264  -23.361 1.00 23.02  ? 415 THR A CA  1 
ATOM   651  C C   . THR A 1 83  ? 7.421   -6.823  -24.733 1.00 20.64  ? 415 THR A C   1 
ATOM   652  O O   . THR A 1 83  ? 6.269   -6.752  -25.169 1.00 24.92  ? 415 THR A O   1 
ATOM   653  C CB  . THR A 1 83  ? 7.449   -7.285  -22.256 1.00 27.87  ? 415 THR A CB  1 
ATOM   654  O OG1 . THR A 1 83  ? 8.021   -6.844  -21.019 1.00 37.39  ? 415 THR A OG1 1 
ATOM   655  C CG2 . THR A 1 83  ? 8.001   -8.644  -22.593 1.00 35.70  ? 415 THR A CG2 1 
ATOM   656  N N   . GLY A 1 84  ? 8.420   -7.367  -25.406 1.00 23.03  ? 416 GLY A N   1 
ATOM   657  C CA  . GLY A 1 84  ? 8.234   -7.932  -26.728 1.00 22.11  ? 416 GLY A CA  1 
ATOM   658  C C   . GLY A 1 84  ? 9.537   -7.894  -27.498 1.00 21.98  ? 416 GLY A C   1 
ATOM   659  O O   . GLY A 1 84  ? 10.553  -7.393  -27.024 1.00 18.76  ? 416 GLY A O   1 
ATOM   660  N N   . LYS A 1 85  ? 9.479   -8.430  -28.719 1.00 19.09  ? 417 LYS A N   1 
ATOM   661  C CA  . LYS A 1 85  ? 10.686  -8.535  -29.534 1.00 19.74  ? 417 LYS A CA  1 
ATOM   662  C C   . LYS A 1 85  ? 11.287  -7.164  -29.819 1.00 22.82  ? 417 LYS A C   1 
ATOM   663  O O   . LYS A 1 85  ? 12.511  -6.994  -29.774 1.00 25.30  ? 417 LYS A O   1 
ATOM   664  C CB  . LYS A 1 85  ? 10.382  -9.272  -30.837 1.00 19.39  ? 417 LYS A CB  1 
ATOM   665  C CG  . LYS A 1 85  ? 10.087  -10.750 -30.649 1.00 19.92  ? 417 LYS A CG  1 
ATOM   666  C CD  . LYS A 1 85  ? 10.461  -11.547 -31.883 1.00 22.62  ? 417 LYS A CD  1 
ATOM   667  C CE  . LYS A 1 85  ? 9.303   -11.682 -32.855 1.00 38.13  ? 417 LYS A CE  1 
ATOM   668  N NZ  . LYS A 1 85  ? 8.495   -12.902 -32.582 1.00 41.56  ? 417 LYS A NZ  1 
ATOM   669  N N   . ILE A 1 86  ? 10.445  -6.175  -30.118 1.00 17.41  ? 418 ILE A N   1 
ATOM   670  C CA  . ILE A 1 86  ? 10.946  -4.825  -30.361 1.00 20.69  ? 418 ILE A CA  1 
ATOM   671  C C   . ILE A 1 86  ? 11.438  -4.195  -29.063 1.00 24.13  ? 418 ILE A C   1 
ATOM   672  O O   . ILE A 1 86  ? 12.518  -3.594  -29.014 1.00 29.92  ? 418 ILE A O   1 
ATOM   673  C CB  . ILE A 1 86  ? 9.861   -3.963  -31.028 1.00 19.00  ? 418 ILE A CB  1 
ATOM   674  C CG1 . ILE A 1 86  ? 9.430   -4.594  -32.350 1.00 19.44  ? 418 ILE A CG1 1 
ATOM   675  C CG2 . ILE A 1 86  ? 10.370  -2.549  -31.253 1.00 14.31  ? 418 ILE A CG2 1 
ATOM   676  C CD1 . ILE A 1 86  ? 10.565  -4.779  -33.332 1.00 23.04  ? 418 ILE A CD1 1 
ATOM   677  N N   . ALA A 1 87  ? 10.655  -4.327  -27.990 1.00 25.91  ? 419 ALA A N   1 
ATOM   678  C CA  . ALA A 1 87  ? 10.991  -3.652  -26.742 1.00 30.20  ? 419 ALA A CA  1 
ATOM   679  C C   . ALA A 1 87  ? 12.201  -4.277  -26.058 1.00 32.11  ? 419 ALA A C   1 
ATOM   680  O O   . ALA A 1 87  ? 12.934  -3.581  -25.346 1.00 26.95  ? 419 ALA A O   1 
ATOM   681  C CB  . ALA A 1 87  ? 9.786   -3.660  -25.802 1.00 15.47  ? 419 ALA A CB  1 
ATOM   682  N N   . ASP A 1 88  ? 12.430  -5.574  -26.256 1.00 19.90  ? 420 ASP A N   1 
ATOM   683  C CA  . ASP A 1 88  ? 13.520  -6.252  -25.567 1.00 27.73  ? 420 ASP A CA  1 
ATOM   684  C C   . ASP A 1 88  ? 14.817  -6.270  -26.364 1.00 29.10  ? 420 ASP A C   1 
ATOM   685  O O   . ASP A 1 88  ? 15.898  -6.223  -25.766 1.00 29.03  ? 420 ASP A O   1 
ATOM   686  C CB  . ASP A 1 88  ? 13.121  -7.692  -25.228 1.00 25.45  ? 420 ASP A CB  1 
ATOM   687  C CG  . ASP A 1 88  ? 11.915  -7.762  -24.312 1.00 33.82  ? 420 ASP A CG  1 
ATOM   688  O OD1 . ASP A 1 88  ? 11.656  -6.774  -23.593 1.00 30.15  ? 420 ASP A OD1 1 
ATOM   689  O OD2 . ASP A 1 88  ? 11.229  -8.806  -24.310 1.00 25.99  ? 420 ASP A OD2 1 
ATOM   690  N N   . TYR A 1 89  ? 14.744  -6.337  -27.694 1.00 23.63  ? 421 TYR A N   1 
ATOM   691  C CA  . TYR A 1 89  ? 15.927  -6.576  -28.507 1.00 25.90  ? 421 TYR A CA  1 
ATOM   692  C C   . TYR A 1 89  ? 16.256  -5.466  -29.495 1.00 22.42  ? 421 TYR A C   1 
ATOM   693  O O   . TYR A 1 89  ? 17.364  -5.469  -30.043 1.00 27.50  ? 421 TYR A O   1 
ATOM   694  C CB  . TYR A 1 89  ? 15.782  -7.897  -29.281 1.00 23.76  ? 421 TYR A CB  1 
ATOM   695  C CG  . TYR A 1 89  ? 15.373  -9.071  -28.418 1.00 22.21  ? 421 TYR A CG  1 
ATOM   696  C CD1 . TYR A 1 89  ? 15.900  -9.242  -27.144 1.00 23.77  ? 421 TYR A CD1 1 
ATOM   697  C CD2 . TYR A 1 89  ? 14.451  -10.003 -28.875 1.00 23.89  ? 421 TYR A CD2 1 
ATOM   698  C CE1 . TYR A 1 89  ? 15.523  -10.309 -26.352 1.00 24.00  ? 421 TYR A CE1 1 
ATOM   699  C CE2 . TYR A 1 89  ? 14.069  -11.073 -28.090 1.00 21.38  ? 421 TYR A CE2 1 
ATOM   700  C CZ  . TYR A 1 89  ? 14.608  -11.222 -26.830 1.00 21.91  ? 421 TYR A CZ  1 
ATOM   701  O OH  . TYR A 1 89  ? 14.230  -12.286 -26.045 1.00 16.84  ? 421 TYR A OH  1 
ATOM   702  N N   . ASN A 1 90  ? 15.345  -4.528  -29.751 1.00 24.14  ? 422 ASN A N   1 
ATOM   703  C CA  . ASN A 1 90  ? 15.590  -3.490  -30.746 1.00 22.48  ? 422 ASN A CA  1 
ATOM   704  C C   . ASN A 1 90  ? 15.591  -2.086  -30.166 1.00 28.54  ? 422 ASN A C   1 
ATOM   705  O O   . ASN A 1 90  ? 16.568  -1.348  -30.349 1.00 25.45  ? 422 ASN A O   1 
ATOM   706  C CB  . ASN A 1 90  ? 14.549  -3.598  -31.871 1.00 17.15  ? 422 ASN A CB  1 
ATOM   707  C CG  . ASN A 1 90  ? 14.662  -4.898  -32.637 1.00 22.02  ? 422 ASN A CG  1 
ATOM   708  O OD1 . ASN A 1 90  ? 15.339  -4.971  -33.662 1.00 20.45  ? 422 ASN A OD1 1 
ATOM   709  N ND2 . ASN A 1 90  ? 14.009  -5.940  -32.134 1.00 17.92  ? 422 ASN A ND2 1 
ATOM   710  N N   . TYR A 1 91  ? 14.531  -1.690  -29.465 1.00 23.71  ? 423 TYR A N   1 
ATOM   711  C CA  . TYR A 1 91  ? 14.451  -0.350  -28.898 1.00 20.89  ? 423 TYR A CA  1 
ATOM   712  C C   . TYR A 1 91  ? 13.686  -0.419  -27.587 1.00 20.62  ? 423 TYR A C   1 
ATOM   713  O O   . TYR A 1 91  ? 12.553  -0.907  -27.555 1.00 22.51  ? 423 TYR A O   1 
ATOM   714  C CB  . TYR A 1 91  ? 13.771  0.626   -29.866 1.00 25.13  ? 423 TYR A CB  1 
ATOM   715  C CG  . TYR A 1 91  ? 13.794  2.068   -29.403 1.00 25.87  ? 423 TYR A CG  1 
ATOM   716  C CD1 . TYR A 1 91  ? 14.890  2.881   -29.659 1.00 20.29  ? 423 TYR A CD1 1 
ATOM   717  C CD2 . TYR A 1 91  ? 12.720  2.615   -28.712 1.00 15.19  ? 423 TYR A CD2 1 
ATOM   718  C CE1 . TYR A 1 91  ? 14.918  4.198   -29.239 1.00 17.92  ? 423 TYR A CE1 1 
ATOM   719  C CE2 . TYR A 1 91  ? 12.739  3.931   -28.288 1.00 15.17  ? 423 TYR A CE2 1 
ATOM   720  C CZ  . TYR A 1 91  ? 13.840  4.718   -28.554 1.00 19.65  ? 423 TYR A CZ  1 
ATOM   721  O OH  . TYR A 1 91  ? 13.866  6.029   -28.135 1.00 23.46  ? 423 TYR A OH  1 
ATOM   722  N N   . LYS A 1 92  ? 14.301  0.077   -26.517 1.00 26.38  ? 424 LYS A N   1 
ATOM   723  C CA  . LYS A 1 92  ? 13.756  -0.045  -25.172 1.00 21.53  ? 424 LYS A CA  1 
ATOM   724  C C   . LYS A 1 92  ? 13.670  1.327   -24.523 1.00 23.74  ? 424 LYS A C   1 
ATOM   725  O O   . LYS A 1 92  ? 14.644  2.088   -24.540 1.00 28.62  ? 424 LYS A O   1 
ATOM   726  C CB  . LYS A 1 92  ? 14.620  -0.980  -24.318 1.00 24.09  ? 424 LYS A CB  1 
ATOM   727  C CG  . LYS A 1 92  ? 14.199  -1.071  -22.862 1.00 27.07  ? 424 LYS A CG  1 
ATOM   728  C CD  . LYS A 1 92  ? 12.797  -1.638  -22.726 1.00 31.78  ? 424 LYS A CD  1 
ATOM   729  C CE  . LYS A 1 92  ? 12.409  -1.801  -21.266 1.00 36.57  ? 424 LYS A CE  1 
ATOM   730  N NZ  . LYS A 1 92  ? 11.013  -2.295  -21.111 1.00 35.90  ? 424 LYS A NZ  1 
ATOM   731  N N   . LEU A 1 93  ? 12.499  1.639   -23.945 1.00 26.47  ? 425 LEU A N   1 
ATOM   732  C CA  . LEU A 1 93  ? 12.292  2.860   -23.185 1.00 19.60  ? 425 LEU A CA  1 
ATOM   733  C C   . LEU A 1 93  ? 12.402  2.582   -21.691 1.00 21.52  ? 425 LEU A C   1 
ATOM   734  O O   . LEU A 1 93  ? 12.047  1.494   -21.227 1.00 26.25  ? 425 LEU A O   1 
ATOM   735  C CB  . LEU A 1 93  ? 10.916  3.464   -23.486 1.00 29.74  ? 425 LEU A CB  1 
ATOM   736  C CG  . LEU A 1 93  ? 10.695  4.065   -24.875 1.00 33.64  ? 425 LEU A CG  1 
ATOM   737  C CD1 . LEU A 1 93  ? 9.265   4.560   -25.017 1.00 28.55  ? 425 LEU A CD1 1 
ATOM   738  C CD2 . LEU A 1 93  ? 11.678  5.194   -25.131 1.00 24.65  ? 425 LEU A CD2 1 
ATOM   739  N N   . PRO A 1 94  ? 12.896  3.539   -20.911 1.00 26.86  ? 426 PRO A N   1 
ATOM   740  C CA  . PRO A 1 94  ? 12.975  3.338   -19.461 1.00 29.42  ? 426 PRO A CA  1 
ATOM   741  C C   . PRO A 1 94  ? 11.596  3.342   -18.821 1.00 32.58  ? 426 PRO A C   1 
ATOM   742  O O   . PRO A 1 94  ? 10.613  3.827   -19.386 1.00 38.57  ? 426 PRO A O   1 
ATOM   743  C CB  . PRO A 1 94  ? 13.815  4.526   -18.981 1.00 25.09  ? 426 PRO A CB  1 
ATOM   744  C CG  . PRO A 1 94  ? 13.610  5.572   -20.023 1.00 24.73  ? 426 PRO A CG  1 
ATOM   745  C CD  . PRO A 1 94  ? 13.471  4.831   -21.323 1.00 27.04  ? 426 PRO A CD  1 
ATOM   746  N N   . ASP A 1 95  ? 11.535  2.774   -17.614 1.00 37.81  ? 427 ASP A N   1 
ATOM   747  C CA  . ASP A 1 95  ? 10.278  2.739   -16.874 1.00 38.52  ? 427 ASP A CA  1 
ATOM   748  C C   . ASP A 1 95  ? 9.820   4.136   -16.475 1.00 32.58  ? 427 ASP A C   1 
ATOM   749  O O   . ASP A 1 95  ? 8.613   4.392   -16.396 1.00 33.03  ? 427 ASP A O   1 
ATOM   750  C CB  . ASP A 1 95  ? 10.421  1.854   -15.636 1.00 47.87  ? 427 ASP A CB  1 
ATOM   751  C CG  . ASP A 1 95  ? 10.653  0.398   -15.986 1.00 60.78  ? 427 ASP A CG  1 
ATOM   752  O OD1 . ASP A 1 95  ? 10.486  0.035   -17.170 1.00 57.77  ? 427 ASP A OD1 1 
ATOM   753  O OD2 . ASP A 1 95  ? 11.007  -0.384  -15.078 1.00 59.16  ? 427 ASP A OD2 1 
ATOM   754  N N   . ASP A 1 96  ? 10.758  5.047   -16.223 1.00 31.92  ? 428 ASP A N   1 
ATOM   755  C CA  . ASP A 1 96  ? 10.452  6.432   -15.870 1.00 31.52  ? 428 ASP A CA  1 
ATOM   756  C C   . ASP A 1 96  ? 10.586  7.357   -17.072 1.00 36.10  ? 428 ASP A C   1 
ATOM   757  O O   . ASP A 1 96  ? 11.035  8.500   -16.944 1.00 32.12  ? 428 ASP A O   1 
ATOM   758  C CB  . ASP A 1 96  ? 11.350  6.897   -14.727 1.00 34.82  ? 428 ASP A CB  1 
ATOM   759  C CG  . ASP A 1 96  ? 12.828  6.744   -15.042 1.00 41.58  ? 428 ASP A CG  1 
ATOM   760  O OD1 . ASP A 1 96  ? 13.164  6.270   -16.148 1.00 39.80  ? 428 ASP A OD1 1 
ATOM   761  O OD2 . ASP A 1 96  ? 13.657  7.097   -14.177 1.00 48.72  ? 428 ASP A OD2 1 
ATOM   762  N N   . PHE A 1 97  ? 10.211  6.870   -18.254 1.00 34.85  ? 429 PHE A N   1 
ATOM   763  C CA  . PHE A 1 97  ? 10.387  7.633   -19.482 1.00 34.63  ? 429 PHE A CA  1 
ATOM   764  C C   . PHE A 1 97  ? 9.613   8.943   -19.428 1.00 28.71  ? 429 PHE A C   1 
ATOM   765  O O   . PHE A 1 97  ? 8.438   8.973   -19.051 1.00 34.50  ? 429 PHE A O   1 
ATOM   766  C CB  . PHE A 1 97  ? 9.936   6.798   -20.681 1.00 28.97  ? 429 PHE A CB  1 
ATOM   767  C CG  . PHE A 1 97  ? 9.913   7.556   -21.977 1.00 30.75  ? 429 PHE A CG  1 
ATOM   768  C CD1 . PHE A 1 97  ? 11.077  8.087   -22.507 1.00 30.09  ? 429 PHE A CD1 1 
ATOM   769  C CD2 . PHE A 1 97  ? 8.728   7.723   -22.675 1.00 31.55  ? 429 PHE A CD2 1 
ATOM   770  C CE1 . PHE A 1 97  ? 11.057  8.780   -23.702 1.00 30.64  ? 429 PHE A CE1 1 
ATOM   771  C CE2 . PHE A 1 97  ? 8.703   8.414   -23.870 1.00 29.10  ? 429 PHE A CE2 1 
ATOM   772  C CZ  . PHE A 1 97  ? 9.869   8.942   -24.385 1.00 26.38  ? 429 PHE A CZ  1 
ATOM   773  N N   . THR A 1 98  ? 10.284  10.029  -19.805 1.00 24.13  ? 430 THR A N   1 
ATOM   774  C CA  . THR A 1 98  ? 9.691   11.362  -19.853 1.00 28.03  ? 430 THR A CA  1 
ATOM   775  C C   . THR A 1 98  ? 9.845   11.879  -21.278 1.00 29.71  ? 430 THR A C   1 
ATOM   776  O O   . THR A 1 98  ? 10.903  12.397  -21.650 1.00 38.49  ? 430 THR A O   1 
ATOM   777  C CB  . THR A 1 98  ? 10.347  12.303  -18.847 1.00 40.18  ? 430 THR A CB  1 
ATOM   778  O OG1 . THR A 1 98  ? 10.202  11.769  -17.525 1.00 40.15  ? 430 THR A OG1 1 
ATOM   779  C CG2 . THR A 1 98  ? 9.696   13.676  -18.905 1.00 34.42  ? 430 THR A CG2 1 
ATOM   780  N N   . GLY A 1 99  ? 8.792   11.733  -22.073 1.00 34.68  ? 431 GLY A N   1 
ATOM   781  C CA  . GLY A 1 99  ? 8.842   12.160  -23.455 1.00 33.90  ? 431 GLY A CA  1 
ATOM   782  C C   . GLY A 1 99  ? 7.608   11.693  -24.200 1.00 27.03  ? 431 GLY A C   1 
ATOM   783  O O   . GLY A 1 99  ? 6.618   11.272  -23.597 1.00 24.88  ? 431 GLY A O   1 
ATOM   784  N N   . CYS A 1 100 ? 7.692   11.767  -25.525 1.00 27.53  ? 432 CYS A N   1 
ATOM   785  C CA  . CYS A 1 100 ? 6.559   11.507  -26.398 1.00 32.73  ? 432 CYS A CA  1 
ATOM   786  C C   . CYS A 1 100 ? 6.902   10.432  -27.418 1.00 29.72  ? 432 CYS A C   1 
ATOM   787  O O   . CYS A 1 100 ? 8.029   10.373  -27.920 1.00 28.72  ? 432 CYS A O   1 
ATOM   788  C CB  . CYS A 1 100 ? 6.125   12.782  -27.125 1.00 26.49  ? 432 CYS A CB  1 
ATOM   789  S SG  . CYS A 1 100 ? 5.370   14.031  -26.066 1.00 42.11  ? 432 CYS A SG  1 
ATOM   790  N N   . VAL A 1 101 ? 5.918   9.590   -27.723 1.00 23.15  ? 433 VAL A N   1 
ATOM   791  C CA  . VAL A 1 101 ? 6.023   8.582   -28.771 1.00 21.21  ? 433 VAL A CA  1 
ATOM   792  C C   . VAL A 1 101 ? 5.019   8.945   -29.854 1.00 22.60  ? 433 VAL A C   1 
ATOM   793  O O   . VAL A 1 101 ? 3.811   9.000   -29.595 1.00 27.16  ? 433 VAL A O   1 
ATOM   794  C CB  . VAL A 1 101 ? 5.769   7.165   -28.234 1.00 21.31  ? 433 VAL A CB  1 
ATOM   795  C CG1 . VAL A 1 101 ? 5.826   6.152   -29.367 1.00 18.33  ? 433 VAL A CG1 1 
ATOM   796  C CG2 . VAL A 1 101 ? 6.781   6.821   -27.153 1.00 25.85  ? 433 VAL A CG2 1 
ATOM   797  N N   . ILE A 1 102 ? 5.518   9.191   -31.062 1.00 26.53  ? 434 ILE A N   1 
ATOM   798  C CA  . ILE A 1 102 ? 4.706   9.648   -32.183 1.00 17.96  ? 434 ILE A CA  1 
ATOM   799  C C   . ILE A 1 102 ? 4.839   8.638   -33.312 1.00 20.53  ? 434 ILE A C   1 
ATOM   800  O O   . ILE A 1 102 ? 5.956   8.295   -33.716 1.00 22.52  ? 434 ILE A O   1 
ATOM   801  C CB  . ILE A 1 102 ? 5.132   11.052  -32.650 1.00 21.37  ? 434 ILE A CB  1 
ATOM   802  C CG1 . ILE A 1 102 ? 5.109   12.033  -31.476 1.00 17.62  ? 434 ILE A CG1 1 
ATOM   803  C CG2 . ILE A 1 102 ? 4.229   11.538  -33.769 1.00 17.13  ? 434 ILE A CG2 1 
ATOM   804  C CD1 . ILE A 1 102 ? 5.782   13.356  -31.772 1.00 21.25  ? 434 ILE A CD1 1 
ATOM   805  N N   . ALA A 1 103 ? 3.703   8.164   -33.820 1.00 19.08  ? 435 ALA A N   1 
ATOM   806  C CA  . ALA A 1 103 ? 3.693   7.182   -34.892 1.00 20.59  ? 435 ALA A CA  1 
ATOM   807  C C   . ALA A 1 103 ? 2.613   7.532   -35.904 1.00 21.16  ? 435 ALA A C   1 
ATOM   808  O O   . ALA A 1 103 ? 1.590   8.133   -35.564 1.00 24.45  ? 435 ALA A O   1 
ATOM   809  C CB  . ALA A 1 103 ? 3.469   5.762   -34.355 1.00 16.19  ? 435 ALA A CB  1 
ATOM   810  N N   . TRP A 1 104 ? 2.854   7.150   -37.155 1.00 21.67  ? 436 TRP A N   1 
ATOM   811  C CA  . TRP A 1 104 ? 1.886   7.342   -38.224 1.00 18.73  ? 436 TRP A CA  1 
ATOM   812  C C   . TRP A 1 104 ? 2.106   6.271   -39.281 1.00 21.76  ? 436 TRP A C   1 
ATOM   813  O O   . TRP A 1 104 ? 3.232   5.816   -39.500 1.00 28.72  ? 436 TRP A O   1 
ATOM   814  C CB  . TRP A 1 104 ? 1.992   8.741   -38.848 1.00 26.78  ? 436 TRP A CB  1 
ATOM   815  C CG  . TRP A 1 104 ? 3.265   8.988   -39.604 1.00 29.81  ? 436 TRP A CG  1 
ATOM   816  C CD1 . TRP A 1 104 ? 3.485   8.772   -40.935 1.00 31.29  ? 436 TRP A CD1 1 
ATOM   817  C CD2 . TRP A 1 104 ? 4.491   9.508   -39.076 1.00 31.70  ? 436 TRP A CD2 1 
ATOM   818  N NE1 . TRP A 1 104 ? 4.771   9.121   -41.266 1.00 21.31  ? 436 TRP A NE1 1 
ATOM   819  C CE2 . TRP A 1 104 ? 5.410   9.576   -40.143 1.00 32.33  ? 436 TRP A CE2 1 
ATOM   820  C CE3 . TRP A 1 104 ? 4.902   9.920   -37.804 1.00 29.74  ? 436 TRP A CE3 1 
ATOM   821  C CZ2 . TRP A 1 104 ? 6.714   10.040  -39.977 1.00 24.05  ? 436 TRP A CZ2 1 
ATOM   822  C CZ3 . TRP A 1 104 ? 6.197   10.380  -37.642 1.00 33.84  ? 436 TRP A CZ3 1 
ATOM   823  C CH2 . TRP A 1 104 ? 7.087   10.435  -38.722 1.00 21.45  ? 436 TRP A CH2 1 
ATOM   824  N N   . ASN A 1 105 ? 1.015   5.867   -39.926 1.00 20.05  ? 437 ASN A N   1 
ATOM   825  C CA  . ASN A 1 105 ? 1.099   4.860   -40.974 1.00 21.57  ? 437 ASN A CA  1 
ATOM   826  C C   . ASN A 1 105 ? 1.855   5.412   -42.176 1.00 34.38  ? 437 ASN A C   1 
ATOM   827  O O   . ASN A 1 105 ? 1.644   6.553   -42.596 1.00 27.81  ? 437 ASN A O   1 
ATOM   828  C CB  . ASN A 1 105 ? -0.304  4.407   -41.385 1.00 22.13  ? 437 ASN A CB  1 
ATOM   829  C CG  . ASN A 1 105 ? -0.288  3.183   -42.285 1.00 27.46  ? 437 ASN A CG  1 
ATOM   830  O OD1 . ASN A 1 105 ? 0.388   3.158   -43.314 1.00 30.36  ? 437 ASN A OD1 1 
ATOM   831  N ND2 . ASN A 1 105 ? -1.037  2.156   -41.897 1.00 25.24  ? 437 ASN A ND2 1 
ATOM   832  N N   . SER A 1 106 ? 2.743   4.592   -42.730 1.00 31.18  ? 438 SER A N   1 
ATOM   833  C CA  . SER A 1 106 ? 3.536   4.950   -43.901 1.00 31.28  ? 438 SER A CA  1 
ATOM   834  C C   . SER A 1 106 ? 3.535   3.805   -44.904 1.00 33.26  ? 438 SER A C   1 
ATOM   835  O O   . SER A 1 106 ? 4.568   3.418   -45.453 1.00 36.99  ? 438 SER A O   1 
ATOM   836  C CB  . SER A 1 106 ? 4.961   5.325   -43.503 1.00 33.18  ? 438 SER A CB  1 
ATOM   837  O OG  . SER A 1 106 ? 5.626   4.231   -42.896 1.00 29.57  ? 438 SER A OG  1 
ATOM   838  N N   . ASN A 1 107 ? 2.349   3.240   -45.144 1.00 34.34  ? 439 ASN A N   1 
ATOM   839  C CA  . ASN A 1 107 ? 2.226   2.156   -46.113 1.00 34.89  ? 439 ASN A CA  1 
ATOM   840  C C   . ASN A 1 107 ? 2.575   2.633   -47.517 1.00 35.41  ? 439 ASN A C   1 
ATOM   841  O O   . ASN A 1 107 ? 3.198   1.901   -48.294 1.00 42.69  ? 439 ASN A O   1 
ATOM   842  C CB  . ASN A 1 107 ? 0.809   1.582   -46.076 1.00 28.23  ? 439 ASN A CB  1 
ATOM   843  C CG  . ASN A 1 107 ? 0.712   0.221   -46.735 1.00 35.84  ? 439 ASN A CG  1 
ATOM   844  O OD1 . ASN A 1 107 ? 1.658   -0.564  -46.704 1.00 34.21  ? 439 ASN A OD1 1 
ATOM   845  N ND2 . ASN A 1 107 ? -0.438  -0.066  -47.334 1.00 37.01  ? 439 ASN A ND2 1 
ATOM   846  N N   . ASN A 1 108 ? 2.177   3.859   -47.861 1.00 32.91  ? 440 ASN A N   1 
ATOM   847  C CA  . ASN A 1 108 ? 2.476   4.395   -49.185 1.00 39.92  ? 440 ASN A CA  1 
ATOM   848  C C   . ASN A 1 108 ? 3.976   4.579   -49.390 1.00 44.13  ? 440 ASN A C   1 
ATOM   849  O O   . ASN A 1 108 ? 4.493   4.331   -50.486 1.00 43.80  ? 440 ASN A O   1 
ATOM   850  C CB  . ASN A 1 108 ? 1.737   5.718   -49.390 1.00 38.96  ? 440 ASN A CB  1 
ATOM   851  C CG  . ASN A 1 108 ? 2.031   6.728   -48.294 1.00 48.94  ? 440 ASN A CG  1 
ATOM   852  O OD1 . ASN A 1 108 ? 2.303   6.361   -47.151 1.00 43.08  ? 440 ASN A OD1 1 
ATOM   853  N ND2 . ASN A 1 108 ? 1.977   8.009   -48.641 1.00 50.62  ? 440 ASN A ND2 1 
ATOM   854  N N   . LEU A 1 109 ? 4.691   5.012   -48.351 1.00 48.12  ? 441 LEU A N   1 
ATOM   855  C CA  . LEU A 1 109 ? 6.107   5.332   -48.499 1.00 33.92  ? 441 LEU A CA  1 
ATOM   856  C C   . LEU A 1 109 ? 6.988   4.092   -48.389 1.00 33.12  ? 441 LEU A C   1 
ATOM   857  O O   . LEU A 1 109 ? 7.860   3.864   -49.234 1.00 47.24  ? 441 LEU A O   1 
ATOM   858  C CB  . LEU A 1 109 ? 6.523   6.366   -47.450 1.00 35.77  ? 441 LEU A CB  1 
ATOM   859  C CG  . LEU A 1 109 ? 5.873   7.749   -47.507 1.00 42.99  ? 441 LEU A CG  1 
ATOM   860  C CD1 . LEU A 1 109 ? 6.274   8.570   -46.291 1.00 31.43  ? 441 LEU A CD1 1 
ATOM   861  C CD2 . LEU A 1 109 ? 6.258   8.469   -48.790 1.00 39.25  ? 441 LEU A CD2 1 
ATOM   862  N N   . ASP A 1 110 ? 6.776   3.280   -47.355 1.00 41.80  ? 442 ASP A N   1 
ATOM   863  C CA  . ASP A 1 110 ? 7.712   2.230   -46.979 1.00 27.14  ? 442 ASP A CA  1 
ATOM   864  C C   . ASP A 1 110 ? 7.291   0.842   -47.445 1.00 33.29  ? 442 ASP A C   1 
ATOM   865  O O   . ASP A 1 110 ? 7.913   -0.146  -47.043 1.00 34.22  ? 442 ASP A O   1 
ATOM   866  C CB  . ASP A 1 110 ? 7.908   2.228   -45.462 1.00 23.26  ? 442 ASP A CB  1 
ATOM   867  C CG  . ASP A 1 110 ? 8.528   3.514   -44.955 1.00 35.94  ? 442 ASP A CG  1 
ATOM   868  O OD1 . ASP A 1 110 ? 9.560   3.938   -45.517 1.00 37.92  ? 442 ASP A OD1 1 
ATOM   869  O OD2 . ASP A 1 110 ? 7.979   4.108   -44.003 1.00 34.21  ? 442 ASP A OD2 1 
ATOM   870  N N   . SER A 1 111 ? 6.261   0.736   -48.278 1.00 37.42  ? 443 SER A N   1 
ATOM   871  C CA  . SER A 1 111 ? 5.792   -0.559  -48.747 1.00 42.44  ? 443 SER A CA  1 
ATOM   872  C C   . SER A 1 111 ? 5.683   -0.557  -50.263 1.00 48.08  ? 443 SER A C   1 
ATOM   873  O O   . SER A 1 111 ? 5.301   0.449   -50.868 1.00 51.16  ? 443 SER A O   1 
ATOM   874  C CB  . SER A 1 111 ? 4.446   -0.920  -48.124 1.00 37.86  ? 443 SER A CB  1 
ATOM   875  O OG  . SER A 1 111 ? 4.132   -2.276  -48.362 1.00 58.09  ? 443 SER A OG  1 
ATOM   876  N N   . LYS A 1 112 ? 6.023   -1.693  -50.871 1.00 44.85  ? 444 LYS A N   1 
ATOM   877  C CA  . LYS A 1 112 ? 6.043   -1.835  -52.319 1.00 51.48  ? 444 LYS A CA  1 
ATOM   878  C C   . LYS A 1 112 ? 5.438   -3.177  -52.702 1.00 47.97  ? 444 LYS A C   1 
ATOM   879  O O   . LYS A 1 112 ? 5.455   -4.129  -51.917 1.00 48.68  ? 444 LYS A O   1 
ATOM   880  C CB  . LYS A 1 112 ? 7.472   -1.720  -52.868 1.00 40.03  ? 444 LYS A CB  1 
ATOM   881  C CG  . LYS A 1 112 ? 8.157   -0.415  -52.500 1.00 54.36  ? 444 LYS A CG  1 
ATOM   882  C CD  . LYS A 1 112 ? 9.589   -0.628  -52.048 1.00 54.37  ? 444 LYS A CD  1 
ATOM   883  C CE  . LYS A 1 112 ? 10.103  0.599   -51.310 1.00 65.54  ? 444 LYS A CE  1 
ATOM   884  N NZ  . LYS A 1 112 ? 11.586  0.602   -51.182 1.00 48.22  ? 444 LYS A NZ  1 
ATOM   885  N N   . VAL A 1 113 ? 4.897   -3.242  -53.922 1.00 42.27  ? 445 VAL A N   1 
ATOM   886  C CA  . VAL A 1 113 ? 4.343   -4.493  -54.424 1.00 43.42  ? 445 VAL A CA  1 
ATOM   887  C C   . VAL A 1 113 ? 5.457   -5.521  -54.544 1.00 42.11  ? 445 VAL A C   1 
ATOM   888  O O   . VAL A 1 113 ? 6.546   -5.228  -55.055 1.00 47.99  ? 445 VAL A O   1 
ATOM   889  C CB  . VAL A 1 113 ? 3.634   -4.266  -55.767 1.00 58.55  ? 445 VAL A CB  1 
ATOM   890  C CG1 . VAL A 1 113 ? 3.101   -5.581  -56.319 1.00 46.96  ? 445 VAL A CG1 1 
ATOM   891  C CG2 . VAL A 1 113 ? 2.507   -3.257  -55.607 1.00 42.00  ? 445 VAL A CG2 1 
ATOM   892  N N   . GLY A 1 114 ? 5.190   -6.735  -54.067 1.00 44.10  ? 446 GLY A N   1 
ATOM   893  C CA  . GLY A 1 114 ? 6.195   -7.770  -53.993 1.00 47.50  ? 446 GLY A CA  1 
ATOM   894  C C   . GLY A 1 114 ? 6.956   -7.816  -52.687 1.00 52.07  ? 446 GLY A C   1 
ATOM   895  O O   . GLY A 1 114 ? 7.667   -8.799  -52.437 1.00 56.70  ? 446 GLY A O   1 
ATOM   896  N N   . GLY A 1 115 ? 6.830   -6.791  -51.847 1.00 45.74  ? 447 GLY A N   1 
ATOM   897  C CA  . GLY A 1 115 ? 7.465   -6.791  -50.546 1.00 50.81  ? 447 GLY A CA  1 
ATOM   898  C C   . GLY A 1 115 ? 8.685   -5.899  -50.447 1.00 49.94  ? 447 GLY A C   1 
ATOM   899  O O   . GLY A 1 115 ? 9.619   -6.020  -51.245 1.00 53.81  ? 447 GLY A O   1 
ATOM   900  N N   . ASN A 1 116 ? 8.685   -4.994  -49.471 1.00 47.56  ? 448 ASN A N   1 
ATOM   901  C CA  . ASN A 1 116 ? 9.849   -4.177  -49.150 1.00 40.98  ? 448 ASN A CA  1 
ATOM   902  C C   . ASN A 1 116 ? 10.576  -4.844  -47.987 1.00 39.72  ? 448 ASN A C   1 
ATOM   903  O O   . ASN A 1 116 ? 10.097  -4.816  -46.849 1.00 47.27  ? 448 ASN A O   1 
ATOM   904  C CB  . ASN A 1 116 ? 9.439   -2.747  -48.804 1.00 33.05  ? 448 ASN A CB  1 
ATOM   905  C CG  . ASN A 1 116 ? 10.622  -1.876  -48.419 1.00 39.19  ? 448 ASN A CG  1 
ATOM   906  O OD1 . ASN A 1 116 ? 11.775  -2.215  -48.687 1.00 37.76  ? 448 ASN A OD1 1 
ATOM   907  N ND2 . ASN A 1 116 ? 10.338  -0.742  -47.787 1.00 36.23  ? 448 ASN A ND2 1 
ATOM   908  N N   . TYR A 1 117 ? 11.731  -5.443  -48.276 1.00 32.03  ? 449 TYR A N   1 
ATOM   909  C CA  . TYR A 1 117 ? 12.489  -6.205  -47.294 1.00 32.24  ? 449 TYR A CA  1 
ATOM   910  C C   . TYR A 1 117 ? 13.699  -5.439  -46.766 1.00 29.47  ? 449 TYR A C   1 
ATOM   911  O O   . TYR A 1 117 ? 14.620  -6.052  -46.215 1.00 42.17  ? 449 TYR A O   1 
ATOM   912  C CB  . TYR A 1 117 ? 12.929  -7.543  -47.893 1.00 36.09  ? 449 TYR A CB  1 
ATOM   913  C CG  . TYR A 1 117 ? 11.783  -8.463  -48.264 1.00 47.78  ? 449 TYR A CG  1 
ATOM   914  C CD1 . TYR A 1 117 ? 11.146  -8.352  -49.494 1.00 50.89  ? 449 TYR A CD1 1 
ATOM   915  C CD2 . TYR A 1 117 ? 11.344  -9.446  -47.386 1.00 46.14  ? 449 TYR A CD2 1 
ATOM   916  C CE1 . TYR A 1 117 ? 10.101  -9.191  -49.837 1.00 51.81  ? 449 TYR A CE1 1 
ATOM   917  C CE2 . TYR A 1 117 ? 10.300  -10.291 -47.721 1.00 54.14  ? 449 TYR A CE2 1 
ATOM   918  C CZ  . TYR A 1 117 ? 9.683   -10.158 -48.947 1.00 56.13  ? 449 TYR A CZ  1 
ATOM   919  O OH  . TYR A 1 117 ? 8.644   -10.995 -49.286 1.00 52.63  ? 449 TYR A OH  1 
ATOM   920  N N   . ASN A 1 118 ? 13.717  -4.115  -46.925 1.00 27.79  ? 450 ASN A N   1 
ATOM   921  C CA  . ASN A 1 118 ? 14.858  -3.317  -46.493 1.00 39.19  ? 450 ASN A CA  1 
ATOM   922  C C   . ASN A 1 118 ? 14.871  -3.042  -44.994 1.00 35.76  ? 450 ASN A C   1 
ATOM   923  O O   . ASN A 1 118 ? 15.934  -2.728  -44.448 1.00 37.47  ? 450 ASN A O   1 
ATOM   924  C CB  . ASN A 1 118 ? 14.887  -1.989  -47.251 1.00 37.05  ? 450 ASN A CB  1 
ATOM   925  C CG  . ASN A 1 118 ? 15.156  -2.171  -48.730 1.00 45.03  ? 450 ASN A CG  1 
ATOM   926  O OD1 . ASN A 1 118 ? 15.939  -3.034  -49.126 1.00 50.51  ? 450 ASN A OD1 1 
ATOM   927  N ND2 . ASN A 1 118 ? 14.503  -1.361  -49.556 1.00 38.61  ? 450 ASN A ND2 1 
ATOM   928  N N   . TYR A 1 119 ? 13.730  -3.148  -44.319 1.00 33.19  ? 451 TYR A N   1 
ATOM   929  C CA  . TYR A 1 119 ? 13.650  -2.846  -42.895 1.00 32.73  ? 451 TYR A CA  1 
ATOM   930  C C   . TYR A 1 119 ? 13.871  -4.113  -42.079 1.00 36.63  ? 451 TYR A C   1 
ATOM   931  O O   . TYR A 1 119 ? 13.224  -5.138  -42.319 1.00 34.09  ? 451 TYR A O   1 
ATOM   932  C CB  . TYR A 1 119 ? 12.301  -2.214  -42.551 1.00 22.02  ? 451 TYR A CB  1 
ATOM   933  C CG  . TYR A 1 119 ? 12.160  -0.791  -43.040 1.00 26.21  ? 451 TYR A CG  1 
ATOM   934  C CD1 . TYR A 1 119 ? 12.776  0.257   -42.369 1.00 30.53  ? 451 TYR A CD1 1 
ATOM   935  C CD2 . TYR A 1 119 ? 11.412  -0.494  -44.172 1.00 33.63  ? 451 TYR A CD2 1 
ATOM   936  C CE1 . TYR A 1 119 ? 12.653  1.560   -42.812 1.00 36.31  ? 451 TYR A CE1 1 
ATOM   937  C CE2 . TYR A 1 119 ? 11.282  0.807   -44.622 1.00 29.39  ? 451 TYR A CE2 1 
ATOM   938  C CZ  . TYR A 1 119 ? 11.904  1.830   -43.937 1.00 37.42  ? 451 TYR A CZ  1 
ATOM   939  O OH  . TYR A 1 119 ? 11.778  3.126   -44.379 1.00 34.04  ? 451 TYR A OH  1 
ATOM   940  N N   . LEU A 1 120 ? 14.782  -4.034  -41.113 1.00 29.68  ? 452 LEU A N   1 
ATOM   941  C CA  . LEU A 1 120 ? 15.195  -5.182  -40.322 1.00 28.26  ? 452 LEU A CA  1 
ATOM   942  C C   . LEU A 1 120 ? 14.899  -4.952  -38.846 1.00 24.45  ? 452 LEU A C   1 
ATOM   943  O O   . LEU A 1 120 ? 14.811  -3.816  -38.374 1.00 21.33  ? 452 LEU A O   1 
ATOM   944  C CB  . LEU A 1 120 ? 16.692  -5.470  -40.500 1.00 31.25  ? 452 LEU A CB  1 
ATOM   945  C CG  . LEU A 1 120 ? 17.205  -5.734  -41.915 1.00 32.29  ? 452 LEU A CG  1 
ATOM   946  C CD1 . LEU A 1 120 ? 18.704  -5.984  -41.896 1.00 27.76  ? 452 LEU A CD1 1 
ATOM   947  C CD2 . LEU A 1 120 ? 16.476  -6.910  -42.534 1.00 25.74  ? 452 LEU A CD2 1 
ATOM   948  N N   . TYR A 1 121 ? 14.743  -6.059  -38.124 1.00 25.35  ? 453 TYR A N   1 
ATOM   949  C CA  . TYR A 1 121 ? 14.616  -6.046  -36.675 1.00 21.50  ? 453 TYR A CA  1 
ATOM   950  C C   . TYR A 1 121 ? 15.406  -7.215  -36.109 1.00 20.98  ? 453 TYR A C   1 
ATOM   951  O O   . TYR A 1 121 ? 15.546  -8.257  -36.755 1.00 20.13  ? 453 TYR A O   1 
ATOM   952  C CB  . TYR A 1 121 ? 13.149  -6.131  -36.226 1.00 18.20  ? 453 TYR A CB  1 
ATOM   953  C CG  . TYR A 1 121 ? 12.442  -7.399  -36.652 1.00 25.09  ? 453 TYR A CG  1 
ATOM   954  C CD1 . TYR A 1 121 ? 11.892  -7.516  -37.922 1.00 28.69  ? 453 TYR A CD1 1 
ATOM   955  C CD2 . TYR A 1 121 ? 12.319  -8.476  -35.784 1.00 17.67  ? 453 TYR A CD2 1 
ATOM   956  C CE1 . TYR A 1 121 ? 11.244  -8.670  -38.316 1.00 28.20  ? 453 TYR A CE1 1 
ATOM   957  C CE2 . TYR A 1 121 ? 11.672  -9.635  -36.170 1.00 22.21  ? 453 TYR A CE2 1 
ATOM   958  C CZ  . TYR A 1 121 ? 11.136  -9.725  -37.437 1.00 20.08  ? 453 TYR A CZ  1 
ATOM   959  O OH  . TYR A 1 121 ? 10.490  -10.874 -37.828 1.00 26.12  ? 453 TYR A OH  1 
ATOM   960  N N   . ARG A 1 122 ? 15.925  -7.035  -34.897 1.00 22.88  ? 454 ARG A N   1 
ATOM   961  C CA  . ARG A 1 122 ? 16.679  -8.095  -34.243 1.00 16.50  ? 454 ARG A CA  1 
ATOM   962  C C   . ARG A 1 122 ? 15.725  -9.147  -33.694 1.00 23.16  ? 454 ARG A C   1 
ATOM   963  O O   . ARG A 1 122 ? 14.759  -8.822  -32.997 1.00 14.86  ? 454 ARG A O   1 
ATOM   964  C CB  . ARG A 1 122 ? 17.551  -7.529  -33.124 1.00 19.28  ? 454 ARG A CB  1 
ATOM   965  C CG  . ARG A 1 122 ? 18.419  -8.578  -32.448 1.00 23.44  ? 454 ARG A CG  1 
ATOM   966  C CD  . ARG A 1 122 ? 19.456  -7.939  -31.542 1.00 31.68  ? 454 ARG A CD  1 
ATOM   967  N NE  . ARG A 1 122 ? 20.256  -6.950  -32.253 1.00 25.95  ? 454 ARG A NE  1 
ATOM   968  C CZ  . ARG A 1 122 ? 21.301  -7.240  -33.016 1.00 32.00  ? 454 ARG A CZ  1 
ATOM   969  N NH1 . ARG A 1 122 ? 21.700  -8.489  -33.197 1.00 26.41  ? 454 ARG A NH1 1 
ATOM   970  N NH2 . ARG A 1 122 ? 21.961  -6.253  -33.616 1.00 24.69  ? 454 ARG A NH2 1 
ATOM   971  N N   . LEU A 1 123 ? 15.999  -10.410 -34.012 1.00 22.27  ? 455 LEU A N   1 
ATOM   972  C CA  . LEU A 1 123 ? 15.148  -11.522 -33.609 1.00 20.81  ? 455 LEU A CA  1 
ATOM   973  C C   . LEU A 1 123 ? 15.692  -12.283 -32.408 1.00 28.36  ? 455 LEU A C   1 
ATOM   974  O O   . LEU A 1 123 ? 14.913  -12.731 -31.561 1.00 27.44  ? 455 LEU A O   1 
ATOM   975  C CB  . LEU A 1 123 ? 14.955  -12.486 -34.785 1.00 17.09  ? 455 LEU A CB  1 
ATOM   976  C CG  . LEU A 1 123 ? 14.015  -13.677 -34.587 1.00 24.99  ? 455 LEU A CG  1 
ATOM   977  C CD1 . LEU A 1 123 ? 12.669  -13.213 -34.070 1.00 19.67  ? 455 LEU A CD1 1 
ATOM   978  C CD2 . LEU A 1 123 ? 13.845  -14.449 -35.888 1.00 33.41  ? 455 LEU A CD2 1 
ATOM   979  N N   . PHE A 1 124 ? 17.011  -12.432 -32.309 1.00 22.50  ? 456 PHE A N   1 
ATOM   980  C CA  . PHE A 1 124 ? 17.642  -13.208 -31.250 1.00 20.62  ? 456 PHE A CA  1 
ATOM   981  C C   . PHE A 1 124 ? 18.606  -12.331 -30.465 1.00 26.48  ? 456 PHE A C   1 
ATOM   982  O O   . PHE A 1 124 ? 19.403  -11.594 -31.054 1.00 34.98  ? 456 PHE A O   1 
ATOM   983  C CB  . PHE A 1 124 ? 18.385  -14.418 -31.823 1.00 17.91  ? 456 PHE A CB  1 
ATOM   984  C CG  . PHE A 1 124 ? 17.485  -15.441 -32.454 1.00 30.15  ? 456 PHE A CG  1 
ATOM   985  C CD1 . PHE A 1 124 ? 16.875  -16.414 -31.679 1.00 27.95  ? 456 PHE A CD1 1 
ATOM   986  C CD2 . PHE A 1 124 ? 17.252  -15.433 -33.819 1.00 22.05  ? 456 PHE A CD2 1 
ATOM   987  C CE1 . PHE A 1 124 ? 16.047  -17.359 -32.253 1.00 20.37  ? 456 PHE A CE1 1 
ATOM   988  C CE2 . PHE A 1 124 ? 16.425  -16.376 -34.399 1.00 21.64  ? 456 PHE A CE2 1 
ATOM   989  C CZ  . PHE A 1 124 ? 15.821  -17.339 -33.614 1.00 24.50  ? 456 PHE A CZ  1 
ATOM   990  N N   . ARG A 1 125 ? 18.526  -12.415 -29.139 1.00 19.72  ? 457 ARG A N   1 
ATOM   991  C CA  . ARG A 1 125 ? 19.491  -11.779 -28.255 1.00 23.19  ? 457 ARG A CA  1 
ATOM   992  C C   . ARG A 1 125 ? 19.435  -12.487 -26.909 1.00 26.32  ? 457 ARG A C   1 
ATOM   993  O O   . ARG A 1 125 ? 18.350  -12.821 -26.426 1.00 37.35  ? 457 ARG A O   1 
ATOM   994  C CB  . ARG A 1 125 ? 19.213  -10.280 -28.091 1.00 20.12  ? 457 ARG A CB  1 
ATOM   995  C CG  . ARG A 1 125 ? 20.439  -9.468  -27.704 1.00 31.06  ? 457 ARG A CG  1 
ATOM   996  C CD  . ARG A 1 125 ? 20.138  -7.979  -27.692 1.00 27.83  ? 457 ARG A CD  1 
ATOM   997  N NE  . ARG A 1 125 ? 21.355  -7.179  -27.638 1.00 27.68  ? 457 ARG A NE  1 
ATOM   998  C CZ  . ARG A 1 125 ? 21.966  -6.816  -26.518 1.00 28.87  ? 457 ARG A CZ  1 
ATOM   999  N NH1 . ARG A 1 125 ? 21.499  -7.168  -25.331 1.00 22.93  ? 457 ARG A NH1 1 
ATOM   1000 N NH2 . ARG A 1 125 ? 23.069  -6.076  -26.591 1.00 29.30  ? 457 ARG A NH2 1 
ATOM   1001 N N   . LYS A 1 126 ? 20.607  -12.716 -26.313 1.00 26.25  ? 458 LYS A N   1 
ATOM   1002 C CA  . LYS A 1 126 ? 20.661  -13.491 -25.078 1.00 24.45  ? 458 LYS A CA  1 
ATOM   1003 C C   . LYS A 1 126 ? 20.122  -12.708 -23.888 1.00 23.67  ? 458 LYS A C   1 
ATOM   1004 O O   . LYS A 1 126 ? 19.618  -13.308 -22.932 1.00 25.41  ? 458 LYS A O   1 
ATOM   1005 C CB  . LYS A 1 126 ? 22.094  -13.951 -24.807 1.00 29.56  ? 458 LYS A CB  1 
ATOM   1006 C CG  . LYS A 1 126 ? 22.713  -14.745 -25.946 1.00 32.35  ? 458 LYS A CG  1 
ATOM   1007 C CD  . LYS A 1 126 ? 24.040  -15.364 -25.539 1.00 37.70  ? 458 LYS A CD  1 
ATOM   1008 C CE  . LYS A 1 126 ? 24.798  -15.889 -26.750 1.00 46.71  ? 458 LYS A CE  1 
ATOM   1009 N NZ  . LYS A 1 126 ? 23.970  -16.811 -27.578 1.00 42.73  ? 458 LYS A NZ  1 
ATOM   1010 N N   . SER A 1 127 ? 20.215  -11.380 -23.922 1.00 23.84  ? 459 SER A N   1 
ATOM   1011 C CA  . SER A 1 127 ? 19.724  -10.544 -22.837 1.00 26.50  ? 459 SER A CA  1 
ATOM   1012 C C   . SER A 1 127 ? 18.992  -9.341  -23.414 1.00 27.07  ? 459 SER A C   1 
ATOM   1013 O O   . SER A 1 127 ? 19.235  -8.925  -24.550 1.00 29.30  ? 459 SER A O   1 
ATOM   1014 C CB  . SER A 1 127 ? 20.862  -10.081 -21.917 1.00 21.72  ? 459 SER A CB  1 
ATOM   1015 O OG  . SER A 1 127 ? 21.791  -9.275  -22.620 1.00 35.61  ? 459 SER A OG  1 
ATOM   1016 N N   . ASN A 1 128 ? 18.086  -8.785  -22.613 1.00 28.57  ? 460 ASN A N   1 
ATOM   1017 C CA  . ASN A 1 128 ? 17.328  -7.616  -23.032 1.00 24.81  ? 460 ASN A CA  1 
ATOM   1018 C C   . ASN A 1 128 ? 18.230  -6.391  -23.135 1.00 31.89  ? 460 ASN A C   1 
ATOM   1019 O O   . ASN A 1 128 ? 19.257  -6.285  -22.460 1.00 31.11  ? 460 ASN A O   1 
ATOM   1020 C CB  . ASN A 1 128 ? 16.188  -7.331  -22.053 1.00 22.77  ? 460 ASN A CB  1 
ATOM   1021 C CG  . ASN A 1 128 ? 15.123  -8.408  -22.066 1.00 31.57  ? 460 ASN A CG  1 
ATOM   1022 O OD1 . ASN A 1 128 ? 15.107  -9.272  -22.942 1.00 29.93  ? 460 ASN A OD1 1 
ATOM   1023 N ND2 . ASN A 1 128 ? 14.216  -8.353  -21.096 1.00 27.89  ? 460 ASN A ND2 1 
ATOM   1024 N N   . LEU A 1 129 ? 17.833  -5.460  -23.999 1.00 30.48  ? 461 LEU A N   1 
ATOM   1025 C CA  . LEU A 1 129 ? 18.553  -4.204  -24.129 1.00 24.67  ? 461 LEU A CA  1 
ATOM   1026 C C   . LEU A 1 129 ? 18.338  -3.324  -22.904 1.00 27.27  ? 461 LEU A C   1 
ATOM   1027 O O   . LEU A 1 129 ? 17.286  -3.357  -22.261 1.00 31.28  ? 461 LEU A O   1 
ATOM   1028 C CB  . LEU A 1 129 ? 18.099  -3.448  -25.378 1.00 24.39  ? 461 LEU A CB  1 
ATOM   1029 C CG  . LEU A 1 129 ? 18.544  -3.960  -26.746 1.00 25.51  ? 461 LEU A CG  1 
ATOM   1030 C CD1 . LEU A 1 129 ? 18.005  -3.050  -27.832 1.00 23.47  ? 461 LEU A CD1 1 
ATOM   1031 C CD2 . LEU A 1 129 ? 20.056  -4.028  -26.815 1.00 32.96  ? 461 LEU A CD2 1 
ATOM   1032 N N   . LYS A 1 130 ? 19.357  -2.534  -22.582 1.00 29.12  ? 462 LYS A N   1 
ATOM   1033 C CA  . LYS A 1 130 ? 19.186  -1.457  -21.628 1.00 26.73  ? 462 LYS A CA  1 
ATOM   1034 C C   . LYS A 1 130 ? 18.389  -0.329  -22.280 1.00 31.15  ? 462 LYS A C   1 
ATOM   1035 O O   . LYS A 1 130 ? 18.306  -0.249  -23.508 1.00 29.13  ? 462 LYS A O   1 
ATOM   1036 C CB  . LYS A 1 130 ? 20.544  -0.948  -21.150 1.00 25.11  ? 462 LYS A CB  1 
ATOM   1037 C CG  . LYS A 1 130 ? 21.371  -1.989  -20.418 1.00 27.64  ? 462 LYS A CG  1 
ATOM   1038 C CD  . LYS A 1 130 ? 20.646  -2.495  -19.183 1.00 39.62  ? 462 LYS A CD  1 
ATOM   1039 C CE  . LYS A 1 130 ? 21.417  -3.621  -18.514 1.00 49.15  ? 462 LYS A CE  1 
ATOM   1040 N NZ  . LYS A 1 130 ? 20.704  -4.149  -17.317 1.00 52.30  ? 462 LYS A NZ  1 
ATOM   1041 N N   . PRO A 1 131 ? 17.763  0.535   -21.481 1.00 26.74  ? 463 PRO A N   1 
ATOM   1042 C CA  . PRO A 1 131 ? 17.043  1.673   -22.064 1.00 29.22  ? 463 PRO A CA  1 
ATOM   1043 C C   . PRO A 1 131 ? 17.959  2.528   -22.929 1.00 25.75  ? 463 PRO A C   1 
ATOM   1044 O O   . PRO A 1 131 ? 19.092  2.835   -22.552 1.00 29.65  ? 463 PRO A O   1 
ATOM   1045 C CB  . PRO A 1 131 ? 16.545  2.441   -20.836 1.00 23.02  ? 463 PRO A CB  1 
ATOM   1046 C CG  . PRO A 1 131 ? 16.408  1.397   -19.784 1.00 16.98  ? 463 PRO A CG  1 
ATOM   1047 C CD  . PRO A 1 131 ? 17.525  0.418   -20.031 1.00 19.18  ? 463 PRO A CD  1 
ATOM   1048 N N   . PHE A 1 132 ? 17.447  2.910   -24.102 1.00 27.90  ? 464 PHE A N   1 
ATOM   1049 C CA  . PHE A 1 132 ? 18.170  3.754   -25.057 1.00 25.21  ? 464 PHE A CA  1 
ATOM   1050 C C   . PHE A 1 132 ? 19.506  3.135   -25.467 1.00 29.52  ? 464 PHE A C   1 
ATOM   1051 O O   . PHE A 1 132 ? 20.517  3.828   -25.595 1.00 37.63  ? 464 PHE A O   1 
ATOM   1052 C CB  . PHE A 1 132 ? 18.373  5.164   -24.499 1.00 32.24  ? 464 PHE A CB  1 
ATOM   1053 C CG  . PHE A 1 132 ? 17.094  5.918   -24.278 1.00 37.49  ? 464 PHE A CG  1 
ATOM   1054 C CD1 . PHE A 1 132 ? 16.098  5.916   -25.241 1.00 31.80  ? 464 PHE A CD1 1 
ATOM   1055 C CD2 . PHE A 1 132 ? 16.883  6.619   -23.103 1.00 28.71  ? 464 PHE A CD2 1 
ATOM   1056 C CE1 . PHE A 1 132 ? 14.919  6.607   -25.040 1.00 28.71  ? 464 PHE A CE1 1 
ATOM   1057 C CE2 . PHE A 1 132 ? 15.705  7.310   -22.895 1.00 32.68  ? 464 PHE A CE2 1 
ATOM   1058 C CZ  . PHE A 1 132 ? 14.721  7.304   -23.864 1.00 31.52  ? 464 PHE A CZ  1 
ATOM   1059 N N   . GLU A 1 133 ? 19.513  1.823   -25.684 1.00 24.95  ? 465 GLU A N   1 
ATOM   1060 C CA  . GLU A 1 133 ? 20.696  1.109   -26.144 1.00 27.34  ? 465 GLU A CA  1 
ATOM   1061 C C   . GLU A 1 133 ? 20.509  0.676   -27.591 1.00 25.37  ? 465 GLU A C   1 
ATOM   1062 O O   . GLU A 1 133 ? 19.448  0.169   -27.967 1.00 23.78  ? 465 GLU A O   1 
ATOM   1063 C CB  . GLU A 1 133 ? 20.987  -0.115  -25.270 1.00 25.00  ? 465 GLU A CB  1 
ATOM   1064 C CG  . GLU A 1 133 ? 22.198  -0.922  -25.727 1.00 39.05  ? 465 GLU A CG  1 
ATOM   1065 C CD  . GLU A 1 133 ? 22.503  -2.099  -24.820 1.00 45.91  ? 465 GLU A CD  1 
ATOM   1066 O OE1 . GLU A 1 133 ? 21.712  -2.359  -23.889 1.00 40.52  ? 465 GLU A OE1 1 
ATOM   1067 O OE2 . GLU A 1 133 ? 23.538  -2.765  -25.037 1.00 47.84  ? 465 GLU A OE2 1 
ATOM   1068 N N   . ARG A 1 134 ? 21.544  0.883   -28.401 1.00 22.02  ? 466 ARG A N   1 
ATOM   1069 C CA  . ARG A 1 134 ? 21.543  0.490   -29.804 1.00 29.44  ? 466 ARG A CA  1 
ATOM   1070 C C   . ARG A 1 134 ? 22.522  -0.661  -29.989 1.00 31.15  ? 466 ARG A C   1 
ATOM   1071 O O   . ARG A 1 134 ? 23.699  -0.542  -29.634 1.00 28.92  ? 466 ARG A O   1 
ATOM   1072 C CB  . ARG A 1 134 ? 21.918  1.666   -30.706 1.00 17.63  ? 466 ARG A CB  1 
ATOM   1073 C CG  . ARG A 1 134 ? 21.790  1.367   -32.191 1.00 18.84  ? 466 ARG A CG  1 
ATOM   1074 C CD  . ARG A 1 134 ? 22.332  2.499   -33.053 1.00 27.55  ? 466 ARG A CD  1 
ATOM   1075 N NE  . ARG A 1 134 ? 21.595  3.745   -32.877 1.00 31.02  ? 466 ARG A NE  1 
ATOM   1076 C CZ  . ARG A 1 134 ? 22.020  4.774   -32.156 1.00 26.19  ? 466 ARG A CZ  1 
ATOM   1077 N NH1 . ARG A 1 134 ? 23.183  4.744   -31.526 1.00 36.69  ? 466 ARG A NH1 1 
ATOM   1078 N NH2 . ARG A 1 134 ? 21.261  5.863   -32.069 1.00 29.62  ? 466 ARG A NH2 1 
ATOM   1079 N N   . ASP A 1 135 ? 22.034  -1.770  -30.542 1.00 27.88  ? 467 ASP A N   1 
ATOM   1080 C CA  . ASP A 1 135 ? 22.848  -2.951  -30.812 1.00 29.58  ? 467 ASP A CA  1 
ATOM   1081 C C   . ASP A 1 135 ? 22.730  -3.274  -32.296 1.00 32.56  ? 467 ASP A C   1 
ATOM   1082 O O   . ASP A 1 135 ? 21.691  -3.767  -32.748 1.00 28.81  ? 467 ASP A O   1 
ATOM   1083 C CB  . ASP A 1 135 ? 22.407  -4.130  -29.945 1.00 27.39  ? 467 ASP A CB  1 
ATOM   1084 C CG  . ASP A 1 135 ? 23.326  -5.332  -30.076 1.00 42.10  ? 467 ASP A CG  1 
ATOM   1085 O OD1 . ASP A 1 135 ? 24.559  -5.138  -30.142 1.00 48.11  ? 467 ASP A OD1 1 
ATOM   1086 O OD2 . ASP A 1 135 ? 22.818  -6.474  -30.095 1.00 38.90  ? 467 ASP A OD2 1 
ATOM   1087 N N   . ILE A 1 136 ? 23.791  -2.997  -33.049 1.00 25.72  ? 468 ILE A N   1 
ATOM   1088 C CA  . ILE A 1 136 ? 23.790  -3.178  -34.494 1.00 31.28  ? 468 ILE A CA  1 
ATOM   1089 C C   . ILE A 1 136 ? 24.630  -4.387  -34.906 1.00 36.94  ? 468 ILE A C   1 
ATOM   1090 O O   . ILE A 1 136 ? 25.014  -4.506  -36.069 1.00 32.04  ? 468 ILE A O   1 
ATOM   1091 C CB  . ILE A 1 136 ? 24.259  -1.904  -35.215 1.00 30.37  ? 468 ILE A CB  1 
ATOM   1092 C CG1 . ILE A 1 136 ? 25.683  -1.543  -34.790 1.00 31.26  ? 468 ILE A CG1 1 
ATOM   1093 C CG2 . ILE A 1 136 ? 23.311  -0.750  -34.927 1.00 30.72  ? 468 ILE A CG2 1 
ATOM   1094 C CD1 . ILE A 1 136 ? 26.251  -0.360  -35.536 1.00 32.93  ? 468 ILE A CD1 1 
ATOM   1095 N N   . SER A 1 137 ? 24.920  -5.285  -33.967 1.00 37.56  ? 469 SER A N   1 
ATOM   1096 C CA  . SER A 1 137 ? 25.720  -6.461  -34.279 1.00 30.96  ? 469 SER A CA  1 
ATOM   1097 C C   . SER A 1 137 ? 24.995  -7.363  -35.270 1.00 36.27  ? 469 SER A C   1 
ATOM   1098 O O   . SER A 1 137 ? 23.778  -7.550  -35.194 1.00 34.78  ? 469 SER A O   1 
ATOM   1099 C CB  . SER A 1 137 ? 26.038  -7.239  -33.001 1.00 31.60  ? 469 SER A CB  1 
ATOM   1100 O OG  . SER A 1 137 ? 26.753  -8.427  -33.292 1.00 46.46  ? 469 SER A OG  1 
ATOM   1101 N N   . THR A 1 138 ? 25.757  -7.919  -36.213 1.00 35.56  ? 470 THR A N   1 
ATOM   1102 C CA  . THR A 1 138 ? 25.236  -8.879  -37.180 1.00 32.09  ? 470 THR A CA  1 
ATOM   1103 C C   . THR A 1 138 ? 25.913  -10.239 -37.053 1.00 36.88  ? 470 THR A C   1 
ATOM   1104 O O   . THR A 1 138 ? 25.808  -11.068 -37.963 1.00 44.39  ? 470 THR A O   1 
ATOM   1105 C CB  . THR A 1 138 ? 25.383  -8.346  -38.608 1.00 37.74  ? 470 THR A CB  1 
ATOM   1106 O OG1 . THR A 1 138 ? 26.620  -7.634  -38.731 1.00 53.01  ? 470 THR A OG1 1 
ATOM   1107 C CG2 . THR A 1 138 ? 24.227  -7.420  -38.955 1.00 39.06  ? 470 THR A CG2 1 
ATOM   1108 N N   . GLU A 1 139 ? 26.608  -10.483 -35.945 1.00 31.91  ? 471 GLU A N   1 
ATOM   1109 C CA  . GLU A 1 139 ? 27.279  -11.759 -35.745 1.00 36.55  ? 471 GLU A CA  1 
ATOM   1110 C C   . GLU A 1 139 ? 26.260  -12.884 -35.607 1.00 40.12  ? 471 GLU A C   1 
ATOM   1111 O O   . GLU A 1 139 ? 25.164  -12.699 -35.070 1.00 42.64  ? 471 GLU A O   1 
ATOM   1112 C CB  . GLU A 1 139 ? 28.172  -11.708 -34.505 1.00 40.15  ? 471 GLU A CB  1 
ATOM   1113 C CG  . GLU A 1 139 ? 29.145  -12.876 -34.396 1.00 52.48  ? 471 GLU A CG  1 
ATOM   1114 C CD  . GLU A 1 139 ? 29.776  -12.990 -33.022 1.00 63.28  ? 471 GLU A CD  1 
ATOM   1115 O OE1 . GLU A 1 139 ? 30.019  -14.130 -32.573 1.00 63.65  ? 471 GLU A OE1 1 
ATOM   1116 O OE2 . GLU A 1 139 ? 30.023  -11.942 -32.389 1.00 66.27  ? 471 GLU A OE2 1 
ATOM   1117 N N   . ILE A 1 140 ? 26.635  -14.064 -36.107 1.00 36.56  ? 472 ILE A N   1 
ATOM   1118 C CA  . ILE A 1 140 ? 25.748  -15.220 -36.051 1.00 29.13  ? 472 ILE A CA  1 
ATOM   1119 C C   . ILE A 1 140 ? 25.412  -15.536 -34.601 1.00 37.90  ? 472 ILE A C   1 
ATOM   1120 O O   . ILE A 1 140 ? 26.299  -15.624 -33.742 1.00 33.41  ? 472 ILE A O   1 
ATOM   1121 C CB  . ILE A 1 140 ? 26.396  -16.422 -36.753 1.00 37.65  ? 472 ILE A CB  1 
ATOM   1122 C CG1 . ILE A 1 140 ? 26.805  -16.051 -38.179 1.00 34.77  ? 472 ILE A CG1 1 
ATOM   1123 C CG2 . ILE A 1 140 ? 25.448  -17.610 -36.760 1.00 33.65  ? 472 ILE A CG2 1 
ATOM   1124 C CD1 . ILE A 1 140 ? 25.658  -15.577 -39.039 1.00 37.56  ? 472 ILE A CD1 1 
ATOM   1125 N N   . TYR A 1 141 ? 24.122  -15.703 -34.324 1.00 31.48  ? 473 TYR A N   1 
ATOM   1126 C CA  . TYR A 1 141 ? 23.653  -15.976 -32.972 1.00 26.23  ? 473 TYR A CA  1 
ATOM   1127 C C   . TYR A 1 141 ? 23.876  -17.449 -32.649 1.00 28.19  ? 473 TYR A C   1 
ATOM   1128 O O   . TYR A 1 141 ? 23.384  -18.329 -33.364 1.00 27.22  ? 473 TYR A O   1 
ATOM   1129 C CB  . TYR A 1 141 ? 22.179  -15.600 -32.846 1.00 22.88  ? 473 TYR A CB  1 
ATOM   1130 C CG  . TYR A 1 141 ? 21.611  -15.733 -31.453 1.00 27.08  ? 473 TYR A CG  1 
ATOM   1131 C CD1 . TYR A 1 141 ? 21.778  -14.722 -30.516 1.00 27.69  ? 473 TYR A CD1 1 
ATOM   1132 C CD2 . TYR A 1 141 ? 20.893  -16.862 -31.080 1.00 21.51  ? 473 TYR A CD2 1 
ATOM   1133 C CE1 . TYR A 1 141 ? 21.255  -14.836 -29.243 1.00 30.22  ? 473 TYR A CE1 1 
ATOM   1134 C CE2 . TYR A 1 141 ? 20.365  -16.984 -29.810 1.00 22.63  ? 473 TYR A CE2 1 
ATOM   1135 C CZ  . TYR A 1 141 ? 20.549  -15.969 -28.895 1.00 25.01  ? 473 TYR A CZ  1 
ATOM   1136 O OH  . TYR A 1 141 ? 20.025  -16.085 -27.629 1.00 26.30  ? 473 TYR A OH  1 
ATOM   1137 N N   . GLN A 1 142 ? 24.621  -17.716 -31.580 1.00 29.05  ? 474 GLN A N   1 
ATOM   1138 C CA  . GLN A 1 142 ? 24.976  -19.079 -31.197 1.00 27.56  ? 474 GLN A CA  1 
ATOM   1139 C C   . GLN A 1 142 ? 23.923  -19.597 -30.225 1.00 31.54  ? 474 GLN A C   1 
ATOM   1140 O O   . GLN A 1 142 ? 23.897  -19.209 -29.054 1.00 31.00  ? 474 GLN A O   1 
ATOM   1141 C CB  . GLN A 1 142 ? 26.374  -19.115 -30.587 1.00 25.93  ? 474 GLN A CB  1 
ATOM   1142 C CG  . GLN A 1 142 ? 26.820  -20.488 -30.118 1.00 39.86  ? 474 GLN A CG  1 
ATOM   1143 C CD  . GLN A 1 142 ? 28.249  -20.489 -29.607 1.00 37.50  ? 474 GLN A CD  1 
ATOM   1144 O OE1 . GLN A 1 142 ? 29.026  -19.580 -29.900 1.00 38.51  ? 474 GLN A OE1 1 
ATOM   1145 N NE2 . GLN A 1 142 ? 28.601  -21.511 -28.836 1.00 32.40  ? 474 GLN A NE2 1 
ATOM   1146 N N   . ALA A 1 143 ? 23.053  -20.479 -30.712 1.00 26.02  ? 475 ALA A N   1 
ATOM   1147 C CA  . ALA A 1 143 ? 21.968  -21.032 -29.911 1.00 28.32  ? 475 ALA A CA  1 
ATOM   1148 C C   . ALA A 1 143 ? 22.337  -22.343 -29.230 1.00 30.89  ? 475 ALA A C   1 
ATOM   1149 O O   . ALA A 1 143 ? 21.508  -22.901 -28.503 1.00 26.27  ? 475 ALA A O   1 
ATOM   1150 C CB  . ALA A 1 143 ? 20.723  -21.235 -30.779 1.00 23.40  ? 475 ALA A CB  1 
ATOM   1151 N N   . GLY A 1 144 ? 23.548  -22.848 -29.448 1.00 28.02  ? 476 GLY A N   1 
ATOM   1152 C CA  . GLY A 1 144 ? 23.989  -24.064 -28.795 1.00 27.82  ? 476 GLY A CA  1 
ATOM   1153 C C   . GLY A 1 144 ? 25.360  -23.913 -28.172 1.00 36.79  ? 476 GLY A C   1 
ATOM   1154 O O   . GLY A 1 144 ? 25.838  -22.790 -27.983 1.00 36.94  ? 476 GLY A O   1 
ATOM   1155 N N   . SER A 1 145 ? 26.005  -25.031 -27.843 1.00 38.13  ? 477 SER A N   1 
ATOM   1156 C CA  . SER A 1 145 ? 27.341  -25.001 -27.264 1.00 33.54  ? 477 SER A CA  1 
ATOM   1157 C C   . SER A 1 145 ? 28.447  -25.026 -28.311 1.00 42.14  ? 477 SER A C   1 
ATOM   1158 O O   . SER A 1 145 ? 29.617  -24.841 -27.957 1.00 45.37  ? 477 SER A O   1 
ATOM   1159 C CB  . SER A 1 145 ? 27.526  -26.179 -26.301 1.00 33.82  ? 477 SER A CB  1 
ATOM   1160 O OG  . SER A 1 145 ? 27.376  -27.417 -26.974 1.00 58.33  ? 477 SER A OG  1 
ATOM   1161 N N   . THR A 1 146 ? 28.112  -25.244 -29.581 1.00 41.89  ? 478 THR A N   1 
ATOM   1162 C CA  . THR A 1 146 ? 29.106  -25.309 -30.647 1.00 39.98  ? 478 THR A CA  1 
ATOM   1163 C C   . THR A 1 146 ? 29.310  -23.927 -31.259 1.00 43.67  ? 478 THR A C   1 
ATOM   1164 O O   . THR A 1 146 ? 28.336  -23.298 -31.686 1.00 47.08  ? 478 THR A O   1 
ATOM   1165 C CB  . THR A 1 146 ? 28.681  -26.289 -31.731 1.00 43.05  ? 478 THR A CB  1 
ATOM   1166 O OG1 . THR A 1 146 ? 28.660  -27.617 -31.196 1.00 45.19  ? 478 THR A OG1 1 
ATOM   1167 C CG2 . THR A 1 146 ? 29.644  -26.236 -32.909 1.00 46.78  ? 478 THR A CG2 1 
ATOM   1168 N N   . PRO A 1 147 ? 30.543  -23.422 -31.305 1.00 56.45  ? 479 PRO A N   1 
ATOM   1169 C CA  . PRO A 1 147 ? 30.789  -22.138 -31.972 1.00 50.47  ? 479 PRO A CA  1 
ATOM   1170 C C   . PRO A 1 147 ? 30.387  -22.193 -33.437 1.00 40.73  ? 479 PRO A C   1 
ATOM   1171 O O   . PRO A 1 147 ? 30.541  -23.216 -34.106 1.00 45.54  ? 479 PRO A O   1 
ATOM   1172 C CB  . PRO A 1 147 ? 32.301  -21.934 -31.805 1.00 52.06  ? 479 PRO A CB  1 
ATOM   1173 C CG  . PRO A 1 147 ? 32.664  -22.761 -30.608 1.00 50.02  ? 479 PRO A CG  1 
ATOM   1174 C CD  . PRO A 1 147 ? 31.762  -23.960 -30.665 1.00 48.82  ? 479 PRO A CD  1 
ATOM   1175 N N   . CYS A 1 148 ? 29.868  -21.073 -33.933 1.00 35.21  ? 480 CYS A N   1 
ATOM   1176 C CA  . CYS A 1 148 ? 29.300  -21.030 -35.277 1.00 39.24  ? 480 CYS A CA  1 
ATOM   1177 C C   . CYS A 1 148 ? 30.327  -20.737 -36.360 1.00 50.96  ? 480 CYS A C   1 
ATOM   1178 O O   . CYS A 1 148 ? 30.112  -21.119 -37.515 1.00 54.20  ? 480 CYS A O   1 
ATOM   1179 C CB  . CYS A 1 148 ? 28.182  -19.987 -35.337 1.00 46.69  ? 480 CYS A CB  1 
ATOM   1180 S SG  . CYS A 1 148 ? 26.756  -20.427 -34.325 1.00 66.94  ? 480 CYS A SG  1 
ATOM   1181 N N   . ASN A 1 149 ? 31.431  -20.067 -36.019 1.00 59.06  ? 481 ASN A N   1 
ATOM   1182 C CA  . ASN A 1 149 ? 32.475  -19.714 -36.983 1.00 55.50  ? 481 ASN A CA  1 
ATOM   1183 C C   . ASN A 1 149 ? 31.927  -18.874 -38.136 1.00 53.97  ? 481 ASN A C   1 
ATOM   1184 O O   . ASN A 1 149 ? 32.427  -18.944 -39.262 1.00 58.82  ? 481 ASN A O   1 
ATOM   1185 C CB  . ASN A 1 149 ? 33.184  -20.962 -37.520 1.00 63.77  ? 481 ASN A CB  1 
ATOM   1186 C CG  . ASN A 1 149 ? 33.981  -21.684 -36.452 1.00 68.27  ? 481 ASN A CG  1 
ATOM   1187 O OD1 . ASN A 1 149 ? 34.832  -21.091 -35.789 1.00 63.74  ? 481 ASN A OD1 1 
ATOM   1188 N ND2 . ASN A 1 149 ? 33.700  -22.970 -36.272 1.00 55.48  ? 481 ASN A ND2 1 
ATOM   1189 N N   . GLY A 1 150 ? 30.892  -18.083 -37.865 1.00 40.25  ? 482 GLY A N   1 
ATOM   1190 C CA  . GLY A 1 150 ? 30.376  -17.135 -38.831 1.00 41.14  ? 482 GLY A CA  1 
ATOM   1191 C C   . GLY A 1 150 ? 29.548  -17.710 -39.958 1.00 47.70  ? 482 GLY A C   1 
ATOM   1192 O O   . GLY A 1 150 ? 29.284  -16.993 -40.930 1.00 44.70  ? 482 GLY A O   1 
ATOM   1193 N N   . VAL A 1 151 ? 29.123  -18.969 -39.868 1.00 44.93  ? 483 VAL A N   1 
ATOM   1194 C CA  . VAL A 1 151 ? 28.312  -19.599 -40.904 1.00 47.11  ? 483 VAL A CA  1 
ATOM   1195 C C   . VAL A 1 151 ? 26.990  -20.042 -40.290 1.00 46.12  ? 483 VAL A C   1 
ATOM   1196 O O   . VAL A 1 151 ? 26.973  -20.697 -39.241 1.00 45.73  ? 483 VAL A O   1 
ATOM   1197 C CB  . VAL A 1 151 ? 29.044  -20.783 -41.568 1.00 58.27  ? 483 VAL A CB  1 
ATOM   1198 C CG1 . VAL A 1 151 ? 29.624  -21.725 -40.526 1.00 46.84  ? 483 VAL A CG1 1 
ATOM   1199 C CG2 . VAL A 1 151 ? 28.108  -21.533 -42.506 1.00 52.29  ? 483 VAL A CG2 1 
ATOM   1200 N N   . GLU A 1 152 ? 25.888  -19.667 -40.935 1.00 47.97  ? 484 GLU A N   1 
ATOM   1201 C CA  . GLU A 1 152 ? 24.564  -20.046 -40.464 1.00 43.33  ? 484 GLU A CA  1 
ATOM   1202 C C   . GLU A 1 152 ? 24.345  -21.546 -40.619 1.00 37.72  ? 484 GLU A C   1 
ATOM   1203 O O   . GLU A 1 152 ? 24.867  -22.184 -41.537 1.00 55.55  ? 484 GLU A O   1 
ATOM   1204 C CB  . GLU A 1 152 ? 23.486  -19.275 -41.227 1.00 43.48  ? 484 GLU A CB  1 
ATOM   1205 C CG  . GLU A 1 152 ? 23.592  -17.765 -41.079 1.00 57.57  ? 484 GLU A CG  1 
ATOM   1206 C CD  . GLU A 1 152 ? 22.748  -17.009 -42.089 1.00 60.98  ? 484 GLU A CD  1 
ATOM   1207 O OE1 . GLU A 1 152 ? 21.520  -17.234 -42.136 1.00 65.86  ? 484 GLU A OE1 1 
ATOM   1208 O OE2 . GLU A 1 152 ? 23.318  -16.191 -42.842 1.00 53.64  ? 484 GLU A OE2 1 
ATOM   1209 N N   . GLY A 1 153 ? 23.561  -22.108 -39.705 1.00 31.00  ? 485 GLY A N   1 
ATOM   1210 C CA  . GLY A 1 153 ? 23.295  -23.538 -39.736 1.00 33.71  ? 485 GLY A CA  1 
ATOM   1211 C C   . GLY A 1 153 ? 22.528  -23.980 -38.510 1.00 36.52  ? 485 GLY A C   1 
ATOM   1212 O O   . GLY A 1 153 ? 21.771  -23.203 -37.916 1.00 35.84  ? 485 GLY A O   1 
ATOM   1213 N N   . PHE A 1 154 ? 22.726  -25.245 -38.144 1.00 34.85  ? 486 PHE A N   1 
ATOM   1214 C CA  . PHE A 1 154 ? 22.082  -25.786 -36.956 1.00 36.92  ? 486 PHE A CA  1 
ATOM   1215 C C   . PHE A 1 154 ? 22.572  -25.058 -35.711 1.00 32.16  ? 486 PHE A C   1 
ATOM   1216 O O   . PHE A 1 154 ? 23.780  -24.920 -35.492 1.00 44.94  ? 486 PHE A O   1 
ATOM   1217 C CB  . PHE A 1 154 ? 22.361  -27.285 -36.846 1.00 31.46  ? 486 PHE A CB  1 
ATOM   1218 C CG  . PHE A 1 154 ? 21.809  -27.916 -35.600 1.00 43.15  ? 486 PHE A CG  1 
ATOM   1219 C CD1 . PHE A 1 154 ? 20.443  -28.079 -35.436 1.00 45.53  ? 486 PHE A CD1 1 
ATOM   1220 C CD2 . PHE A 1 154 ? 22.658  -28.357 -34.599 1.00 33.82  ? 486 PHE A CD2 1 
ATOM   1221 C CE1 . PHE A 1 154 ? 19.934  -28.663 -34.290 1.00 41.96  ? 486 PHE A CE1 1 
ATOM   1222 C CE2 . PHE A 1 154 ? 22.155  -28.943 -33.453 1.00 38.33  ? 486 PHE A CE2 1 
ATOM   1223 C CZ  . PHE A 1 154 ? 20.792  -29.095 -33.298 1.00 42.81  ? 486 PHE A CZ  1 
ATOM   1224 N N   . ASN A 1 155 ? 21.624  -24.589 -34.897 1.00 36.25  ? 487 ASN A N   1 
ATOM   1225 C CA  . ASN A 1 155 ? 21.893  -23.802 -33.694 1.00 34.35  ? 487 ASN A CA  1 
ATOM   1226 C C   . ASN A 1 155 ? 22.693  -22.536 -33.989 1.00 30.61  ? 487 ASN A C   1 
ATOM   1227 O O   . ASN A 1 155 ? 23.306  -21.961 -33.084 1.00 29.69  ? 487 ASN A O   1 
ATOM   1228 C CB  . ASN A 1 155 ? 22.607  -24.635 -32.622 1.00 37.88  ? 487 ASN A CB  1 
ATOM   1229 C CG  . ASN A 1 155 ? 21.677  -25.609 -31.926 1.00 36.77  ? 487 ASN A CG  1 
ATOM   1230 O OD1 . ASN A 1 155 ? 20.456  -25.460 -31.975 1.00 29.95  ? 487 ASN A OD1 1 
ATOM   1231 N ND2 . ASN A 1 155 ? 22.252  -26.606 -31.264 1.00 37.51  ? 487 ASN A ND2 1 
ATOM   1232 N N   . CYS A 1 156 ? 22.697  -22.085 -35.242 1.00 27.36  ? 488 CYS A N   1 
ATOM   1233 C CA  . CYS A 1 156 ? 23.421  -20.883 -35.653 1.00 33.13  ? 488 CYS A CA  1 
ATOM   1234 C C   . CYS A 1 156 ? 22.485  -20.049 -36.522 1.00 33.35  ? 488 CYS A C   1 
ATOM   1235 O O   . CYS A 1 156 ? 22.329  -20.317 -37.717 1.00 30.73  ? 488 CYS A O   1 
ATOM   1236 C CB  . CYS A 1 156 ? 24.707  -21.242 -36.388 1.00 34.49  ? 488 CYS A CB  1 
ATOM   1237 S SG  . CYS A 1 156 ? 25.940  -22.004 -35.313 1.00 38.55  ? 488 CYS A SG  1 
ATOM   1238 N N   . TYR A 1 157 ? 21.871  -19.038 -35.916 1.00 27.38  ? 489 TYR A N   1 
ATOM   1239 C CA  . TYR A 1 157 ? 20.840  -18.237 -36.555 1.00 25.66  ? 489 TYR A CA  1 
ATOM   1240 C C   . TYR A 1 157 ? 21.359  -16.831 -36.818 1.00 26.26  ? 489 TYR A C   1 
ATOM   1241 O O   . TYR A 1 157 ? 22.056  -16.252 -35.979 1.00 29.41  ? 489 TYR A O   1 
ATOM   1242 C CB  . TYR A 1 157 ? 19.585  -18.162 -35.680 1.00 29.59  ? 489 TYR A CB  1 
ATOM   1243 C CG  . TYR A 1 157 ? 19.117  -19.495 -35.142 1.00 31.11  ? 489 TYR A CG  1 
ATOM   1244 C CD1 . TYR A 1 157 ? 19.200  -20.648 -35.912 1.00 25.13  ? 489 TYR A CD1 1 
ATOM   1245 C CD2 . TYR A 1 157 ? 18.592  -19.600 -33.860 1.00 28.77  ? 489 TYR A CD2 1 
ATOM   1246 C CE1 . TYR A 1 157 ? 18.773  -21.867 -35.421 1.00 29.60  ? 489 TYR A CE1 1 
ATOM   1247 C CE2 . TYR A 1 157 ? 18.163  -20.814 -33.361 1.00 30.74  ? 489 TYR A CE2 1 
ATOM   1248 C CZ  . TYR A 1 157 ? 18.256  -21.943 -34.146 1.00 29.09  ? 489 TYR A CZ  1 
ATOM   1249 O OH  . TYR A 1 157 ? 17.829  -23.154 -33.654 1.00 48.27  ? 489 TYR A OH  1 
ATOM   1250 N N   . PHE A 1 158 ? 21.024  -16.290 -37.981 1.00 31.50  ? 490 PHE A N   1 
ATOM   1251 C CA  . PHE A 1 158 ? 21.325  -14.891 -38.246 1.00 31.32  ? 490 PHE A CA  1 
ATOM   1252 C C   . PHE A 1 158 ? 20.453  -14.021 -37.348 1.00 29.89  ? 490 PHE A C   1 
ATOM   1253 O O   . PHE A 1 158 ? 19.236  -14.233 -37.280 1.00 31.74  ? 490 PHE A O   1 
ATOM   1254 C CB  . PHE A 1 158 ? 21.095  -14.549 -39.715 1.00 32.01  ? 490 PHE A CB  1 
ATOM   1255 C CG  . PHE A 1 158 ? 21.820  -13.313 -40.164 1.00 48.94  ? 490 PHE A CG  1 
ATOM   1256 C CD1 . PHE A 1 158 ? 23.178  -13.355 -40.437 1.00 46.93  ? 490 PHE A CD1 1 
ATOM   1257 C CD2 . PHE A 1 158 ? 21.149  -12.109 -40.307 1.00 37.29  ? 490 PHE A CD2 1 
ATOM   1258 C CE1 . PHE A 1 158 ? 23.854  -12.221 -40.846 1.00 46.92  ? 490 PHE A CE1 1 
ATOM   1259 C CE2 . PHE A 1 158 ? 21.820  -10.971 -40.717 1.00 41.74  ? 490 PHE A CE2 1 
ATOM   1260 C CZ  . PHE A 1 158 ? 23.174  -11.028 -40.987 1.00 52.18  ? 490 PHE A CZ  1 
ATOM   1261 N N   . PRO A 1 159 ? 21.028  -13.043 -36.643 1.00 33.88  ? 491 PRO A N   1 
ATOM   1262 C CA  . PRO A 1 159 ? 20.266  -12.353 -35.591 1.00 27.17  ? 491 PRO A CA  1 
ATOM   1263 C C   . PRO A 1 159 ? 19.167  -11.443 -36.109 1.00 21.74  ? 491 PRO A C   1 
ATOM   1264 O O   . PRO A 1 159 ? 18.291  -11.064 -35.323 1.00 25.36  ? 491 PRO A O   1 
ATOM   1265 C CB  . PRO A 1 159 ? 21.345  -11.550 -34.854 1.00 31.78  ? 491 PRO A CB  1 
ATOM   1266 C CG  . PRO A 1 159 ? 22.371  -11.277 -35.907 1.00 31.87  ? 491 PRO A CG  1 
ATOM   1267 C CD  . PRO A 1 159 ? 22.389  -12.499 -36.792 1.00 32.71  ? 491 PRO A CD  1 
ATOM   1268 N N   . LEU A 1 160 ? 19.175  -11.083 -37.388 1.00 27.78  ? 492 LEU A N   1 
ATOM   1269 C CA  . LEU A 1 160 ? 18.244  -10.102 -37.924 1.00 31.95  ? 492 LEU A CA  1 
ATOM   1270 C C   . LEU A 1 160 ? 17.216  -10.767 -38.830 1.00 28.90  ? 492 LEU A C   1 
ATOM   1271 O O   . LEU A 1 160 ? 17.493  -11.780 -39.480 1.00 31.11  ? 492 LEU A O   1 
ATOM   1272 C CB  . LEU A 1 160 ? 18.984  -9.005  -38.695 1.00 24.42  ? 492 LEU A CB  1 
ATOM   1273 C CG  . LEU A 1 160 ? 20.048  -8.230  -37.914 1.00 34.39  ? 492 LEU A CG  1 
ATOM   1274 C CD1 . LEU A 1 160 ? 20.545  -7.047  -38.727 1.00 28.96  ? 492 LEU A CD1 1 
ATOM   1275 C CD2 . LEU A 1 160 ? 19.514  -7.772  -36.565 1.00 26.53  ? 492 LEU A CD2 1 
ATOM   1276 N N   . GLN A 1 161 ? 16.020  -10.181 -38.865 1.00 27.14  ? 493 GLN A N   1 
ATOM   1277 C CA  . GLN A 1 161 ? 14.919  -10.662 -39.684 1.00 28.95  ? 493 GLN A CA  1 
ATOM   1278 C C   . GLN A 1 161 ? 14.320  -9.489  -40.448 1.00 30.84  ? 493 GLN A C   1 
ATOM   1279 O O   . GLN A 1 161 ? 14.371  -8.343  -39.994 1.00 32.98  ? 493 GLN A O   1 
ATOM   1280 C CB  . GLN A 1 161 ? 13.839  -11.344 -38.829 1.00 35.81  ? 493 GLN A CB  1 
ATOM   1281 C CG  . GLN A 1 161 ? 12.839  -12.184 -39.612 1.00 42.70  ? 493 GLN A CG  1 
ATOM   1282 C CD  . GLN A 1 161 ? 13.326  -13.598 -39.858 1.00 42.31  ? 493 GLN A CD  1 
ATOM   1283 O OE1 . GLN A 1 161 ? 14.506  -13.902 -39.684 1.00 51.57  ? 493 GLN A OE1 1 
ATOM   1284 N NE2 . GLN A 1 161 ? 12.413  -14.476 -40.256 1.00 54.22  ? 493 GLN A NE2 1 
ATOM   1285 N N   . SER A 1 162 ? 13.750  -9.785  -41.613 1.00 37.88  ? 494 SER A N   1 
ATOM   1286 C CA  . SER A 1 162 ? 13.242  -8.766  -42.520 1.00 36.37  ? 494 SER A CA  1 
ATOM   1287 C C   . SER A 1 162 ? 11.726  -8.657  -42.419 1.00 31.54  ? 494 SER A C   1 
ATOM   1288 O O   . SER A 1 162 ? 11.021  -9.669  -42.355 1.00 31.99  ? 494 SER A O   1 
ATOM   1289 C CB  . SER A 1 162 ? 13.641  -9.084  -43.963 1.00 35.53  ? 494 SER A CB  1 
ATOM   1290 O OG  . SER A 1 162 ? 14.264  -7.973  -44.581 1.00 46.30  ? 494 SER A OG  1 
ATOM   1291 N N   . TYR A 1 163 ? 11.229  -7.422  -42.398 1.00 28.08  ? 495 TYR A N   1 
ATOM   1292 C CA  . TYR A 1 163 ? 9.795   -7.196  -42.516 1.00 38.32  ? 495 TYR A CA  1 
ATOM   1293 C C   . TYR A 1 163 ? 9.345   -7.405  -43.958 1.00 40.63  ? 495 TYR A C   1 
ATOM   1294 O O   . TYR A 1 163 ? 9.986   -6.932  -44.900 1.00 42.85  ? 495 TYR A O   1 
ATOM   1295 C CB  . TYR A 1 163 ? 9.430   -5.782  -42.065 1.00 29.20  ? 495 TYR A CB  1 
ATOM   1296 C CG  . TYR A 1 163 ? 9.472   -5.547  -40.570 1.00 32.32  ? 495 TYR A CG  1 
ATOM   1297 C CD1 . TYR A 1 163 ? 8.600   -6.212  -39.716 1.00 24.26  ? 495 TYR A CD1 1 
ATOM   1298 C CD2 . TYR A 1 163 ? 10.361  -4.635  -40.017 1.00 36.43  ? 495 TYR A CD2 1 
ATOM   1299 C CE1 . TYR A 1 163 ? 8.629   -5.990  -38.351 1.00 20.51  ? 495 TYR A CE1 1 
ATOM   1300 C CE2 . TYR A 1 163 ? 10.396  -4.405  -38.654 1.00 28.16  ? 495 TYR A CE2 1 
ATOM   1301 C CZ  . TYR A 1 163 ? 9.527   -5.085  -37.826 1.00 34.19  ? 495 TYR A CZ  1 
ATOM   1302 O OH  . TYR A 1 163 ? 9.559   -4.860  -36.468 1.00 31.32  ? 495 TYR A OH  1 
ATOM   1303 N N   . GLY A 1 164 ? 8.237   -8.122  -44.128 1.00 39.11  ? 496 GLY A N   1 
ATOM   1304 C CA  . GLY A 1 164 ? 7.657   -8.311  -45.444 1.00 44.60  ? 496 GLY A CA  1 
ATOM   1305 C C   . GLY A 1 164 ? 6.599   -7.279  -45.783 1.00 47.00  ? 496 GLY A C   1 
ATOM   1306 O O   . GLY A 1 164 ? 5.426   -7.623  -45.960 1.00 49.23  ? 496 GLY A O   1 
ATOM   1307 N N   . PHE A 1 165 ? 6.999   -6.012  -45.881 1.00 34.45  ? 497 PHE A N   1 
ATOM   1308 C CA  . PHE A 1 165 ? 6.051   -4.915  -46.063 1.00 39.50  ? 497 PHE A CA  1 
ATOM   1309 C C   . PHE A 1 165 ? 5.438   -4.968  -47.458 1.00 47.26  ? 497 PHE A C   1 
ATOM   1310 O O   . PHE A 1 165 ? 6.111   -4.684  -48.454 1.00 44.19  ? 497 PHE A O   1 
ATOM   1311 C CB  . PHE A 1 165 ? 6.746   -3.579  -45.824 1.00 35.43  ? 497 PHE A CB  1 
ATOM   1312 C CG  . PHE A 1 165 ? 7.024   -3.291  -44.376 1.00 40.21  ? 497 PHE A CG  1 
ATOM   1313 C CD1 . PHE A 1 165 ? 6.112   -3.653  -43.398 1.00 43.13  ? 497 PHE A CD1 1 
ATOM   1314 C CD2 . PHE A 1 165 ? 8.199   -2.667  -43.992 1.00 40.17  ? 497 PHE A CD2 1 
ATOM   1315 C CE1 . PHE A 1 165 ? 6.363   -3.393  -42.064 1.00 31.86  ? 497 PHE A CE1 1 
ATOM   1316 C CE2 . PHE A 1 165 ? 8.458   -2.404  -42.659 1.00 42.53  ? 497 PHE A CE2 1 
ATOM   1317 C CZ  . PHE A 1 165 ? 7.538   -2.768  -41.693 1.00 37.96  ? 497 PHE A CZ  1 
ATOM   1318 N N   . GLN A 1 166 ? 4.153   -5.319  -47.528 1.00 50.61  ? 498 GLN A N   1 
ATOM   1319 C CA  . GLN A 1 166 ? 3.370   -5.325  -48.751 1.00 40.64  ? 498 GLN A CA  1 
ATOM   1320 C C   . GLN A 1 166 ? 2.141   -4.439  -48.582 1.00 43.23  ? 498 GLN A C   1 
ATOM   1321 O O   . GLN A 1 166 ? 1.488   -4.485  -47.534 1.00 48.50  ? 498 GLN A O   1 
ATOM   1322 C CB  . GLN A 1 166 ? 2.934   -6.750  -49.122 1.00 43.91  ? 498 GLN A CB  1 
ATOM   1323 C CG  . GLN A 1 166 ? 4.092   -7.726  -49.255 1.00 53.27  ? 498 GLN A CG  1 
ATOM   1324 C CD  . GLN A 1 166 ? 3.636   -9.169  -49.314 1.00 58.30  ? 498 GLN A CD  1 
ATOM   1325 O OE1 . GLN A 1 166 ? 2.618   -9.486  -49.928 1.00 59.74  ? 498 GLN A OE1 1 
ATOM   1326 N NE2 . GLN A 1 166 ? 4.385   -10.053 -48.664 1.00 56.67  ? 498 GLN A NE2 1 
ATOM   1327 N N   . PRO A 1 167 ? 1.808   -3.618  -49.582 1.00 41.89  ? 499 PRO A N   1 
ATOM   1328 C CA  . PRO A 1 167 ? 0.733   -2.628  -49.392 1.00 42.99  ? 499 PRO A CA  1 
ATOM   1329 C C   . PRO A 1 167 ? -0.641  -3.234  -49.164 1.00 42.02  ? 499 PRO A C   1 
ATOM   1330 O O   . PRO A 1 167 ? -1.520  -2.546  -48.631 1.00 37.28  ? 499 PRO A O   1 
ATOM   1331 C CB  . PRO A 1 167 ? 0.776   -1.812  -50.692 1.00 35.05  ? 499 PRO A CB  1 
ATOM   1332 C CG  . PRO A 1 167 ? 1.374   -2.737  -51.696 1.00 41.74  ? 499 PRO A CG  1 
ATOM   1333 C CD  . PRO A 1 167 ? 2.373   -3.570  -50.941 1.00 49.24  ? 499 PRO A CD  1 
ATOM   1334 N N   . THR A 1 168 ? -0.860  -4.489  -49.546 1.00 41.85  ? 500 THR A N   1 
ATOM   1335 C CA  . THR A 1 168 ? -2.161  -5.125  -49.392 1.00 43.43  ? 500 THR A CA  1 
ATOM   1336 C C   . THR A 1 168 ? -2.317  -5.854  -48.064 1.00 51.32  ? 500 THR A C   1 
ATOM   1337 O O   . THR A 1 168 ? -3.370  -6.454  -47.824 1.00 54.36  ? 500 THR A O   1 
ATOM   1338 C CB  . THR A 1 168 ? -2.412  -6.103  -50.544 1.00 40.00  ? 500 THR A CB  1 
ATOM   1339 O OG1 . THR A 1 168 ? -1.366  -7.082  -50.578 1.00 46.55  ? 500 THR A OG1 1 
ATOM   1340 C CG2 . THR A 1 168 ? -2.452  -5.361  -51.870 1.00 38.04  ? 500 THR A CG2 1 
ATOM   1341 N N   . ASN A 1 169 ? -1.305  -5.823  -47.201 1.00 57.25  ? 501 ASN A N   1 
ATOM   1342 C CA  . ASN A 1 169 ? -1.396  -6.483  -45.910 1.00 55.32  ? 501 ASN A CA  1 
ATOM   1343 C C   . ASN A 1 169 ? -2.267  -5.673  -44.952 1.00 46.44  ? 501 ASN A C   1 
ATOM   1344 O O   . ASN A 1 169 ? -2.604  -4.511  -45.199 1.00 37.56  ? 501 ASN A O   1 
ATOM   1345 C CB  . ASN A 1 169 ? -0.004  -6.695  -45.315 1.00 53.23  ? 501 ASN A CB  1 
ATOM   1346 C CG  . ASN A 1 169 ? 0.807   -7.724  -46.079 1.00 56.58  ? 501 ASN A CG  1 
ATOM   1347 O OD1 . ASN A 1 169 ? 0.253   -8.609  -46.733 1.00 65.98  ? 501 ASN A OD1 1 
ATOM   1348 N ND2 . ASN A 1 169 ? 2.127   -7.618  -45.994 1.00 44.20  ? 501 ASN A ND2 1 
ATOM   1349 N N   . GLY A 1 170 ? -2.631  -6.306  -43.839 1.00 35.80  ? 502 GLY A N   1 
ATOM   1350 C CA  . GLY A 1 170 ? -3.460  -5.660  -42.845 1.00 23.97  ? 502 GLY A CA  1 
ATOM   1351 C C   . GLY A 1 170 ? -2.748  -4.511  -42.156 1.00 37.72  ? 502 GLY A C   1 
ATOM   1352 O O   . GLY A 1 170 ? -1.530  -4.347  -42.235 1.00 48.14  ? 502 GLY A O   1 
ATOM   1353 N N   . VAL A 1 171 ? -3.546  -3.703  -41.452 1.00 30.43  ? 503 VAL A N   1 
ATOM   1354 C CA  . VAL A 1 171 ? -3.034  -2.480  -40.836 1.00 34.63  ? 503 VAL A CA  1 
ATOM   1355 C C   . VAL A 1 171 ? -1.913  -2.797  -39.854 1.00 36.17  ? 503 VAL A C   1 
ATOM   1356 O O   . VAL A 1 171 ? -0.887  -2.106  -39.817 1.00 42.50  ? 503 VAL A O   1 
ATOM   1357 C CB  . VAL A 1 171 ? -4.181  -1.706  -40.159 1.00 38.03  ? 503 VAL A CB  1 
ATOM   1358 C CG1 . VAL A 1 171 ? -3.631  -0.609  -39.263 1.00 42.05  ? 503 VAL A CG1 1 
ATOM   1359 C CG2 . VAL A 1 171 ? -5.111  -1.119  -41.208 1.00 39.53  ? 503 VAL A CG2 1 
ATOM   1360 N N   . GLY A 1 172 ? -2.085  -3.847  -39.049 1.00 30.86  ? 504 GLY A N   1 
ATOM   1361 C CA  . GLY A 1 172 ? -1.036  -4.233  -38.122 1.00 29.69  ? 504 GLY A CA  1 
ATOM   1362 C C   . GLY A 1 172 ? 0.250   -4.638  -38.815 1.00 38.89  ? 504 GLY A C   1 
ATOM   1363 O O   . GLY A 1 172 ? 1.340   -4.449  -38.269 1.00 43.93  ? 504 GLY A O   1 
ATOM   1364 N N   . TYR A 1 173 ? 0.145   -5.202  -40.017 1.00 42.92  ? 505 TYR A N   1 
ATOM   1365 C CA  . TYR A 1 173 ? 1.327   -5.608  -40.766 1.00 29.21  ? 505 TYR A CA  1 
ATOM   1366 C C   . TYR A 1 173 ? 1.963   -4.455  -41.531 1.00 35.46  ? 505 TYR A C   1 
ATOM   1367 O O   . TYR A 1 173 ? 3.100   -4.590  -41.995 1.00 45.84  ? 505 TYR A O   1 
ATOM   1368 C CB  . TYR A 1 173 ? 0.971   -6.728  -41.747 1.00 34.27  ? 505 TYR A CB  1 
ATOM   1369 C CG  . TYR A 1 173 ? 0.540   -8.034  -41.111 1.00 50.96  ? 505 TYR A CG  1 
ATOM   1370 C CD1 . TYR A 1 173 ? -0.611  -8.110  -40.332 1.00 54.36  ? 505 TYR A CD1 1 
ATOM   1371 C CD2 . TYR A 1 173 ? 1.266   -9.199  -41.318 1.00 54.77  ? 505 TYR A CD2 1 
ATOM   1372 C CE1 . TYR A 1 173 ? -1.010  -9.304  -39.760 1.00 47.39  ? 505 TYR A CE1 1 
ATOM   1373 C CE2 . TYR A 1 173 ? 0.873   -10.397 -40.752 1.00 54.20  ? 505 TYR A CE2 1 
ATOM   1374 C CZ  . TYR A 1 173 ? -0.265  -10.443 -39.976 1.00 52.77  ? 505 TYR A CZ  1 
ATOM   1375 O OH  . TYR A 1 173 ? -0.660  -11.632 -39.414 1.00 45.65  ? 505 TYR A OH  1 
ATOM   1376 N N   . GLN A 1 174 ? 1.257   -3.337  -41.677 1.00 34.15  ? 506 GLN A N   1 
ATOM   1377 C CA  . GLN A 1 174 ? 1.756   -2.237  -42.483 1.00 37.75  ? 506 GLN A CA  1 
ATOM   1378 C C   . GLN A 1 174 ? 2.864   -1.487  -41.744 1.00 33.64  ? 506 GLN A C   1 
ATOM   1379 O O   . GLN A 1 174 ? 2.879   -1.442  -40.511 1.00 36.55  ? 506 GLN A O   1 
ATOM   1380 C CB  . GLN A 1 174 ? 0.621   -1.278  -42.834 1.00 30.45  ? 506 GLN A CB  1 
ATOM   1381 C CG  . GLN A 1 174 ? -0.411  -1.863  -43.785 1.00 24.95  ? 506 GLN A CG  1 
ATOM   1382 C CD  . GLN A 1 174 ? -1.583  -0.930  -44.014 1.00 36.35  ? 506 GLN A CD  1 
ATOM   1383 O OE1 . GLN A 1 174 ? -1.530  0.249   -43.661 1.00 24.72  ? 506 GLN A OE1 1 
ATOM   1384 N NE2 . GLN A 1 174 ? -2.653  -1.455  -44.603 1.00 30.55  ? 506 GLN A NE2 1 
ATOM   1385 N N   . PRO A 1 175 ? 3.812   -0.905  -42.476 1.00 35.53  ? 507 PRO A N   1 
ATOM   1386 C CA  . PRO A 1 175 ? 4.884   -0.150  -41.820 1.00 33.33  ? 507 PRO A CA  1 
ATOM   1387 C C   . PRO A 1 175 ? 4.358   1.106   -41.145 1.00 24.32  ? 507 PRO A C   1 
ATOM   1388 O O   . PRO A 1 175 ? 3.431   1.761   -41.626 1.00 24.50  ? 507 PRO A O   1 
ATOM   1389 C CB  . PRO A 1 175 ? 5.833   0.194   -42.974 1.00 36.52  ? 507 PRO A CB  1 
ATOM   1390 C CG  . PRO A 1 175 ? 4.964   0.178   -44.186 1.00 41.74  ? 507 PRO A CG  1 
ATOM   1391 C CD  . PRO A 1 175 ? 3.951   -0.903  -43.942 1.00 30.99  ? 507 PRO A CD  1 
ATOM   1392 N N   . TYR A 1 176 ? 4.971   1.435   -40.011 1.00 27.37  ? 508 TYR A N   1 
ATOM   1393 C CA  . TYR A 1 176 ? 4.672   2.649   -39.268 1.00 22.70  ? 508 TYR A CA  1 
ATOM   1394 C C   . TYR A 1 176 ? 5.978   3.349   -38.937 1.00 26.87  ? 508 TYR A C   1 
ATOM   1395 O O   . TYR A 1 176 ? 6.918   2.716   -38.446 1.00 29.64  ? 508 TYR A O   1 
ATOM   1396 C CB  . TYR A 1 176 ? 3.897   2.344   -37.980 1.00 23.04  ? 508 TYR A CB  1 
ATOM   1397 C CG  . TYR A 1 176 ? 2.401   2.236   -38.167 1.00 28.13  ? 508 TYR A CG  1 
ATOM   1398 C CD1 . TYR A 1 176 ? 1.844   1.184   -38.882 1.00 22.39  ? 508 TYR A CD1 1 
ATOM   1399 C CD2 . TYR A 1 176 ? 1.546   3.183   -37.620 1.00 19.11  ? 508 TYR A CD2 1 
ATOM   1400 C CE1 . TYR A 1 176 ? 0.477   1.081   -39.054 1.00 18.97  ? 508 TYR A CE1 1 
ATOM   1401 C CE2 . TYR A 1 176 ? 0.178   3.089   -37.785 1.00 17.84  ? 508 TYR A CE2 1 
ATOM   1402 C CZ  . TYR A 1 176 ? -0.351  2.036   -38.502 1.00 19.79  ? 508 TYR A CZ  1 
ATOM   1403 O OH  . TYR A 1 176 ? -1.714  1.938   -38.669 1.00 27.13  ? 508 TYR A OH  1 
ATOM   1404 N N   . ARG A 1 177 ? 6.040   4.648   -39.209 1.00 25.43  ? 509 ARG A N   1 
ATOM   1405 C CA  . ARG A 1 177 ? 7.199   5.450   -38.848 1.00 25.45  ? 509 ARG A CA  1 
ATOM   1406 C C   . ARG A 1 177 ? 7.001   6.006   -37.445 1.00 21.70  ? 509 ARG A C   1 
ATOM   1407 O O   . ARG A 1 177 ? 5.959   6.597   -37.145 1.00 24.59  ? 509 ARG A O   1 
ATOM   1408 C CB  . ARG A 1 177 ? 7.418   6.576   -39.859 1.00 26.98  ? 509 ARG A CB  1 
ATOM   1409 C CG  . ARG A 1 177 ? 7.781   6.065   -41.243 1.00 36.03  ? 509 ARG A CG  1 
ATOM   1410 C CD  . ARG A 1 177 ? 8.238   7.173   -42.175 1.00 31.88  ? 509 ARG A CD  1 
ATOM   1411 N NE  . ARG A 1 177 ? 8.861   6.620   -43.373 1.00 35.15  ? 509 ARG A NE  1 
ATOM   1412 C CZ  . ARG A 1 177 ? 9.419   7.343   -44.334 1.00 32.40  ? 509 ARG A CZ  1 
ATOM   1413 N NH1 . ARG A 1 177 ? 9.441   8.665   -44.282 1.00 28.98  ? 509 ARG A NH1 1 
ATOM   1414 N NH2 . ARG A 1 177 ? 9.972   6.723   -45.373 1.00 24.58  ? 509 ARG A NH2 1 
ATOM   1415 N N   . VAL A 1 178 ? 7.999   5.807   -36.590 1.00 19.05  ? 510 VAL A N   1 
ATOM   1416 C CA  . VAL A 1 178 ? 7.916   6.145   -35.175 1.00 17.84  ? 510 VAL A CA  1 
ATOM   1417 C C   . VAL A 1 178 ? 9.003   7.159   -34.858 1.00 21.55  ? 510 VAL A C   1 
ATOM   1418 O O   . VAL A 1 178 ? 10.160  6.980   -35.254 1.00 22.71  ? 510 VAL A O   1 
ATOM   1419 C CB  . VAL A 1 178 ? 8.062   4.897   -34.284 1.00 17.46  ? 510 VAL A CB  1 
ATOM   1420 C CG1 . VAL A 1 178 ? 7.895   5.266   -32.818 1.00 13.93  ? 510 VAL A CG1 1 
ATOM   1421 C CG2 . VAL A 1 178 ? 7.060   3.828   -34.692 1.00 14.56  ? 510 VAL A CG2 1 
ATOM   1422 N N   . VAL A 1 179 ? 8.629   8.225   -34.155 1.00 16.84  ? 511 VAL A N   1 
ATOM   1423 C CA  . VAL A 1 179 ? 9.574   9.207   -33.640 1.00 20.40  ? 511 VAL A CA  1 
ATOM   1424 C C   . VAL A 1 179 ? 9.368   9.320   -32.137 1.00 24.33  ? 511 VAL A C   1 
ATOM   1425 O O   . VAL A 1 179 ? 8.246   9.558   -31.676 1.00 23.87  ? 511 VAL A O   1 
ATOM   1426 C CB  . VAL A 1 179 ? 9.409   10.578  -34.322 1.00 24.13  ? 511 VAL A CB  1 
ATOM   1427 C CG1 . VAL A 1 179 ? 10.326  11.598  -33.673 1.00 21.09  ? 511 VAL A CG1 1 
ATOM   1428 C CG2 . VAL A 1 179 ? 9.704   10.467  -35.809 1.00 25.80  ? 511 VAL A CG2 1 
ATOM   1429 N N   . VAL A 1 180 ? 10.447  9.151   -31.379 1.00 20.64  ? 512 VAL A N   1 
ATOM   1430 C CA  . VAL A 1 180 ? 10.410  9.192   -29.921 1.00 23.82  ? 512 VAL A CA  1 
ATOM   1431 C C   . VAL A 1 180 ? 11.193  10.414  -29.463 1.00 31.02  ? 512 VAL A C   1 
ATOM   1432 O O   . VAL A 1 180 ? 12.376  10.563  -29.794 1.00 33.25  ? 512 VAL A O   1 
ATOM   1433 C CB  . VAL A 1 180 ? 10.980  7.907   -29.302 1.00 21.55  ? 512 VAL A CB  1 
ATOM   1434 C CG1 . VAL A 1 180 ? 10.904  7.971   -27.784 1.00 19.69  ? 512 VAL A CG1 1 
ATOM   1435 C CG2 . VAL A 1 180 ? 10.237  6.690   -29.828 1.00 21.60  ? 512 VAL A CG2 1 
ATOM   1436 N N   . LEU A 1 181 ? 10.537  11.280  -28.698 1.00 16.94  ? 513 LEU A N   1 
ATOM   1437 C CA  . LEU A 1 181 ? 11.150  12.493  -28.175 1.00 28.57  ? 513 LEU A CA  1 
ATOM   1438 C C   . LEU A 1 181 ? 11.597  12.259  -26.739 1.00 31.75  ? 513 LEU A C   1 
ATOM   1439 O O   . LEU A 1 181 ? 10.794  11.851  -25.894 1.00 26.63  ? 513 LEU A O   1 
ATOM   1440 C CB  . LEU A 1 181 ? 10.174  13.670  -28.238 1.00 27.79  ? 513 LEU A CB  1 
ATOM   1441 C CG  . LEU A 1 181 ? 10.250  14.613  -29.443 1.00 25.89  ? 513 LEU A CG  1 
ATOM   1442 C CD1 . LEU A 1 181 ? 10.185  13.850  -30.754 1.00 28.42  ? 513 LEU A CD1 1 
ATOM   1443 C CD2 . LEU A 1 181 ? 9.137   15.648  -29.372 1.00 27.62  ? 513 LEU A CD2 1 
ATOM   1444 N N   . SER A 1 182 ? 12.875  12.511  -26.470 1.00 30.47  ? 514 SER A N   1 
ATOM   1445 C CA  . SER A 1 182 ? 13.442  12.398  -25.133 1.00 27.72  ? 514 SER A CA  1 
ATOM   1446 C C   . SER A 1 182 ? 13.933  13.768  -24.693 1.00 36.82  ? 514 SER A C   1 
ATOM   1447 O O   . SER A 1 182 ? 14.622  14.456  -25.453 1.00 41.22  ? 514 SER A O   1 
ATOM   1448 C CB  . SER A 1 182 ? 14.588  11.383  -25.098 1.00 27.35  ? 514 SER A CB  1 
ATOM   1449 O OG  . SER A 1 182 ? 14.153  10.107  -25.534 1.00 41.41  ? 514 SER A OG  1 
ATOM   1450 N N   . PHE A 1 183 ? 13.578  14.160  -23.473 1.00 44.22  ? 515 PHE A N   1 
ATOM   1451 C CA  . PHE A 1 183 ? 13.905  15.478  -22.942 1.00 43.73  ? 515 PHE A CA  1 
ATOM   1452 C C   . PHE A 1 183 ? 14.824  15.309  -21.742 1.00 53.77  ? 515 PHE A C   1 
ATOM   1453 O O   . PHE A 1 183 ? 14.474  14.616  -20.780 1.00 73.60  ? 515 PHE A O   1 
ATOM   1454 C CB  . PHE A 1 183 ? 12.634  16.241  -22.569 1.00 44.94  ? 515 PHE A CB  1 
ATOM   1455 C CG  . PHE A 1 183 ? 11.654  16.354  -23.701 1.00 46.31  ? 515 PHE A CG  1 
ATOM   1456 C CD1 . PHE A 1 183 ? 11.725  17.411  -24.594 1.00 45.65  ? 515 PHE A CD1 1 
ATOM   1457 C CD2 . PHE A 1 183 ? 10.675  15.392  -23.887 1.00 33.11  ? 515 PHE A CD2 1 
ATOM   1458 C CE1 . PHE A 1 183 ? 10.831  17.513  -25.642 1.00 39.88  ? 515 PHE A CE1 1 
ATOM   1459 C CE2 . PHE A 1 183 ? 9.780   15.487  -24.933 1.00 44.42  ? 515 PHE A CE2 1 
ATOM   1460 C CZ  . PHE A 1 183 ? 9.858   16.549  -25.813 1.00 37.92  ? 515 PHE A CZ  1 
ATOM   1461 N N   . GLU A 1 184 ? 15.990  15.947  -21.799 1.00 61.11  ? 516 GLU A N   1 
ATOM   1462 C CA  . GLU A 1 184 ? 17.053  15.755  -20.823 1.00 68.90  ? 516 GLU A CA  1 
ATOM   1463 C C   . GLU A 1 184 ? 17.402  17.082  -20.167 1.00 78.05  ? 516 GLU A C   1 
ATOM   1464 O O   . GLU A 1 184 ? 17.607  18.087  -20.857 1.00 74.19  ? 516 GLU A O   1 
ATOM   1465 C CB  . GLU A 1 184 ? 18.288  15.144  -21.494 1.00 74.47  ? 516 GLU A CB  1 
ATOM   1466 C CG  . GLU A 1 184 ? 19.597  15.371  -20.758 1.00 79.27  ? 516 GLU A CG  1 
ATOM   1467 C CD  . GLU A 1 184 ? 20.767  14.697  -21.448 1.00 74.46  ? 516 GLU A CD  1 
ATOM   1468 O OE1 . GLU A 1 184 ? 20.791  13.449  -21.496 1.00 73.11  ? 516 GLU A OE1 1 
ATOM   1469 O OE2 . GLU A 1 184 ? 21.655  15.415  -21.955 1.00 62.31  ? 516 GLU A OE2 1 
ATOM   1470 N N   . LEU A 1 185 ? 17.470  17.080  -18.837 1.00 85.73  ? 517 LEU A N   1 
ATOM   1471 C CA  . LEU A 1 185 ? 17.873  18.244  -18.049 1.00 89.31  ? 517 LEU A CA  1 
ATOM   1472 C C   . LEU A 1 185 ? 19.089  17.832  -17.225 1.00 94.19  ? 517 LEU A C   1 
ATOM   1473 O O   . LEU A 1 185 ? 18.952  17.189  -16.179 1.00 88.94  ? 517 LEU A O   1 
ATOM   1474 C CB  . LEU A 1 185 ? 16.723  18.735  -17.169 1.00 89.48  ? 517 LEU A CB  1 
ATOM   1475 C CG  . LEU A 1 185 ? 16.848  20.101  -16.483 1.00 85.98  ? 517 LEU A CG  1 
ATOM   1476 C CD1 . LEU A 1 185 ? 17.567  19.999  -15.143 1.00 83.03  ? 517 LEU A CD1 1 
ATOM   1477 C CD2 . LEU A 1 185 ? 17.549  21.099  -17.395 1.00 77.72  ? 517 LEU A CD2 1 
ATOM   1478 N N   . LEU A 1 186 ? 20.279  18.202  -17.697 1.00 96.58  ? 518 LEU A N   1 
ATOM   1479 C CA  . LEU A 1 186 ? 21.535  17.818  -17.066 1.00 100.34 ? 518 LEU A CA  1 
ATOM   1480 C C   . LEU A 1 186 ? 22.027  18.831  -16.040 1.00 111.33 ? 518 LEU A C   1 
ATOM   1481 O O   . LEU A 1 186 ? 23.179  18.736  -15.603 1.00 117.73 ? 518 LEU A O   1 
ATOM   1482 C CB  . LEU A 1 186 ? 22.621  17.612  -18.126 1.00 94.91  ? 518 LEU A CB  1 
ATOM   1483 C CG  . LEU A 1 186 ? 22.674  16.278  -18.867 1.00 90.80  ? 518 LEU A CG  1 
ATOM   1484 C CD1 . LEU A 1 186 ? 23.874  16.250  -19.800 1.00 90.42  ? 518 LEU A CD1 1 
ATOM   1485 C CD2 . LEU A 1 186 ? 22.733  15.123  -17.881 1.00 84.29  ? 518 LEU A CD2 1 
ATOM   1486 N N   . HIS A 1 187 ? 21.194  19.801  -15.665 1.00 109.62 ? 519 HIS A N   1 
ATOM   1487 C CA  . HIS A 1 187 ? 21.553  20.906  -14.780 1.00 117.05 ? 519 HIS A CA  1 
ATOM   1488 C C   . HIS A 1 187 ? 22.644  21.793  -15.373 1.00 120.87 ? 519 HIS A C   1 
ATOM   1489 O O   . HIS A 1 187 ? 23.212  22.636  -14.666 1.00 115.73 ? 519 HIS A O   1 
ATOM   1490 C CB  . HIS A 1 187 ? 21.970  20.403  -13.389 1.00 121.85 ? 519 HIS A CB  1 
ATOM   1491 C CG  . HIS A 1 187 ? 21.565  21.310  -12.268 1.00 128.77 ? 519 HIS A CG  1 
ATOM   1492 N ND1 . HIS A 1 187 ? 21.994  21.128  -10.971 1.00 124.21 ? 519 HIS A ND1 1 
ATOM   1493 C CD2 . HIS A 1 187 ? 20.768  22.405  -12.250 1.00 126.68 ? 519 HIS A CD2 1 
ATOM   1494 C CE1 . HIS A 1 187 ? 21.482  22.074  -10.203 1.00 122.24 ? 519 HIS A CE1 1 
ATOM   1495 N NE2 . HIS A 1 187 ? 20.734  22.861  -10.955 1.00 124.69 ? 519 HIS A NE2 1 
ATOM   1496 N N   . ALA A 1 188 ? 22.949  21.625  -16.650 1.00 119.42 ? 520 ALA A N   1 
ATOM   1497 C CA  . ALA A 1 188 ? 23.859  22.488  -17.386 1.00 111.65 ? 520 ALA A CA  1 
ATOM   1498 C C   . ALA A 1 188 ? 23.082  23.666  -17.940 1.00 103.48 ? 520 ALA A C   1 
ATOM   1499 O O   . ALA A 1 188 ? 21.864  23.746  -17.776 1.00 98.48  ? 520 ALA A O   1 
ATOM   1500 C CB  . ALA A 1 188 ? 24.540  21.687  -18.491 1.00 102.62 ? 520 ALA A CB  1 
ATOM   1501 N N   . PRO A 1 189 ? 23.763  24.630  -18.561 1.00 103.51 ? 521 PRO A N   1 
ATOM   1502 C CA  . PRO A 1 189 ? 23.042  25.705  -19.252 1.00 89.37  ? 521 PRO A CA  1 
ATOM   1503 C C   . PRO A 1 189 ? 22.106  25.141  -20.310 1.00 88.54  ? 521 PRO A C   1 
ATOM   1504 O O   . PRO A 1 189 ? 22.506  24.350  -21.169 1.00 87.69  ? 521 PRO A O   1 
ATOM   1505 C CB  . PRO A 1 189 ? 24.165  26.553  -19.872 1.00 85.82  ? 521 PRO A CB  1 
ATOM   1506 C CG  . PRO A 1 189 ? 25.408  25.723  -19.741 1.00 90.28  ? 521 PRO A CG  1 
ATOM   1507 C CD  . PRO A 1 189 ? 25.215  24.875  -18.549 1.00 98.64  ? 521 PRO A CD  1 
ATOM   1508 N N   . ALA A 1 190 ? 20.843  25.543  -20.222 1.00 80.73  ? 522 ALA A N   1 
ATOM   1509 C CA  . ALA A 1 190 ? 19.817  25.047  -21.125 1.00 69.49  ? 522 ALA A CA  1 
ATOM   1510 C C   . ALA A 1 190 ? 19.878  25.799  -22.445 1.00 71.91  ? 522 ALA A C   1 
ATOM   1511 O O   . ALA A 1 190 ? 20.012  27.026  -22.474 1.00 83.11  ? 522 ALA A O   1 
ATOM   1512 C CB  . ALA A 1 190 ? 18.438  25.196  -20.488 1.00 57.75  ? 522 ALA A CB  1 
ATOM   1513 N N   . THR A 1 191 ? 19.786  25.052  -23.543 1.00 64.83  ? 523 THR A N   1 
ATOM   1514 C CA  . THR A 1 191 ? 19.890  25.631  -24.873 1.00 69.79  ? 523 THR A CA  1 
ATOM   1515 C C   . THR A 1 191 ? 18.741  25.259  -25.801 1.00 64.43  ? 523 THR A C   1 
ATOM   1516 O O   . THR A 1 191 ? 18.710  25.745  -26.936 1.00 61.75  ? 523 THR A O   1 
ATOM   1517 C CB  . THR A 1 191 ? 21.221  25.228  -25.530 1.00 68.35  ? 523 THR A CB  1 
ATOM   1518 O OG1 . THR A 1 191 ? 21.542  23.875  -25.182 1.00 77.63  ? 523 THR A OG1 1 
ATOM   1519 C CG2 . THR A 1 191 ? 22.346  26.152  -25.084 1.00 61.60  ? 523 THR A CG2 1 
ATOM   1520 N N   . VAL A 1 192 ? 17.806  24.424  -25.363 1.00 60.12  ? 524 VAL A N   1 
ATOM   1521 C CA  . VAL A 1 192 ? 16.650  24.037  -26.173 1.00 53.36  ? 524 VAL A CA  1 
ATOM   1522 C C   . VAL A 1 192 ? 15.414  24.546  -25.440 1.00 57.52  ? 524 VAL A C   1 
ATOM   1523 O O   . VAL A 1 192 ? 14.862  23.873  -24.566 1.00 58.02  ? 524 VAL A O   1 
ATOM   1524 C CB  . VAL A 1 192 ? 16.576  22.527  -26.412 1.00 53.76  ? 524 VAL A CB  1 
ATOM   1525 C CG1 . VAL A 1 192 ? 15.496  22.206  -27.436 1.00 37.68  ? 524 VAL A CG1 1 
ATOM   1526 C CG2 . VAL A 1 192 ? 17.923  21.994  -26.863 1.00 55.83  ? 524 VAL A CG2 1 
ATOM   1527 N N   . CYS A 1 193 ? 14.968  25.744  -25.800 1.00 60.28  ? 525 CYS A N   1 
ATOM   1528 C CA  . CYS A 1 193 ? 13.791  26.365  -25.214 1.00 65.49  ? 525 CYS A CA  1 
ATOM   1529 C C   . CYS A 1 193 ? 12.749  26.616  -26.296 1.00 59.15  ? 525 CYS A C   1 
ATOM   1530 O O   . CYS A 1 193 ? 13.034  26.561  -27.495 1.00 58.59  ? 525 CYS A O   1 
ATOM   1531 C CB  . CYS A 1 193 ? 14.146  27.684  -24.515 1.00 63.14  ? 525 CYS A CB  1 
ATOM   1532 S SG  . CYS A 1 193 ? 15.392  27.589  -23.204 1.00 92.11  ? 525 CYS A SG  1 
ATOM   1533 N N   . GLY A 1 194 ? 11.524  26.893  -25.856 1.00 54.95  ? 526 GLY A N   1 
ATOM   1534 C CA  . GLY A 1 194 ? 10.480  27.299  -26.762 1.00 64.70  ? 526 GLY A CA  1 
ATOM   1535 C C   . GLY A 1 194 ? 10.565  28.771  -27.095 1.00 62.70  ? 526 GLY A C   1 
ATOM   1536 O O   . GLY A 1 194 ? 11.419  29.515  -26.592 1.00 67.78  ? 526 GLY A O   1 
ATOM   1537 N N   . PRO A 1 195 ? 9.668   29.214  -27.976 1.00 65.32  ? 527 PRO A N   1 
ATOM   1538 C CA  . PRO A 1 195 ? 9.639   30.634  -28.344 1.00 68.60  ? 527 PRO A CA  1 
ATOM   1539 C C   . PRO A 1 195 ? 9.291   31.512  -27.151 1.00 68.05  ? 527 PRO A C   1 
ATOM   1540 O O   . PRO A 1 195 ? 8.530   31.122  -26.263 1.00 67.47  ? 527 PRO A O   1 
ATOM   1541 C CB  . PRO A 1 195 ? 8.552   30.702  -29.424 1.00 61.59  ? 527 PRO A CB  1 
ATOM   1542 C CG  . PRO A 1 195 ? 8.406   29.295  -29.919 1.00 59.82  ? 527 PRO A CG  1 
ATOM   1543 C CD  . PRO A 1 195 ? 8.680   28.427  -28.731 1.00 59.22  ? 527 PRO A CD  1 
ATOM   1544 N N   . LYS A 1 196 ? 9.862   32.712  -27.140 1.00 71.48  ? 528 LYS A N   1 
ATOM   1545 C CA  . LYS A 1 196 ? 9.558   33.689  -26.101 1.00 75.36  ? 528 LYS A CA  1 
ATOM   1546 C C   . LYS A 1 196 ? 8.593   34.747  -26.628 1.00 70.46  ? 528 LYS A C   1 
ATOM   1547 O O   . LYS A 1 196 ? 8.925   35.505  -27.539 1.00 78.19  ? 528 LYS A O   1 
ATOM   1548 C CB  . LYS A 1 196 ? 10.838  34.349  -25.584 1.00 78.78  ? 528 LYS A CB  1 
ATOM   1549 C CG  . LYS A 1 196 ? 10.590  35.547  -24.681 1.00 82.78  ? 528 LYS A CG  1 
ATOM   1550 C CD  . LYS A 1 196 ? 9.762   35.165  -23.463 1.00 83.34  ? 528 LYS A CD  1 
ATOM   1551 C CE  . LYS A 1 196 ? 9.146   36.394  -22.814 1.00 77.13  ? 528 LYS A CE  1 
ATOM   1552 N NZ  . LYS A 1 196 ? 8.246   37.118  -23.755 1.00 73.63  ? 528 LYS A NZ  1 
ATOM   1553 N N   . GLU B 2 1   ? -7.878  24.536  -28.942 1.00 62.67  ? 1   GLU H N   1 
ATOM   1554 C CA  . GLU B 2 1   ? -8.236  24.110  -27.594 1.00 56.26  ? 1   GLU H CA  1 
ATOM   1555 C C   . GLU B 2 1   ? -9.179  22.912  -27.634 1.00 47.98  ? 1   GLU H C   1 
ATOM   1556 O O   . GLU B 2 1   ? -10.133 22.886  -28.412 1.00 59.23  ? 1   GLU H O   1 
ATOM   1557 C CB  . GLU B 2 1   ? -8.878  25.263  -26.819 1.00 60.33  ? 1   GLU H CB  1 
ATOM   1558 C CG  . GLU B 2 1   ? -9.234  24.922  -25.381 1.00 72.21  ? 1   GLU H CG  1 
ATOM   1559 C CD  . GLU B 2 1   ? -9.820  26.103  -24.633 1.00 86.64  ? 1   GLU H CD  1 
ATOM   1560 O OE1 . GLU B 2 1   ? -9.832  27.218  -25.196 1.00 95.25  ? 1   GLU H OE1 1 
ATOM   1561 O OE2 . GLU B 2 1   ? -10.270 25.915  -23.483 1.00 92.03  ? 1   GLU H OE2 1 
ATOM   1562 N N   . VAL B 2 2   ? -8.901  21.923  -26.792 1.00 41.42  ? 2   VAL H N   1 
ATOM   1563 C CA  . VAL B 2 2   ? -9.707  20.709  -26.734 1.00 39.69  ? 2   VAL H CA  1 
ATOM   1564 C C   . VAL B 2 2   ? -10.920 20.946  -25.848 1.00 30.76  ? 2   VAL H C   1 
ATOM   1565 O O   . VAL B 2 2   ? -10.816 21.537  -24.766 1.00 30.17  ? 2   VAL H O   1 
ATOM   1566 C CB  . VAL B 2 2   ? -8.863  19.527  -26.224 1.00 25.69  ? 2   VAL H CB  1 
ATOM   1567 C CG1 . VAL B 2 2   ? -9.744  18.318  -25.948 1.00 22.75  ? 2   VAL H CG1 1 
ATOM   1568 C CG2 . VAL B 2 2   ? -7.785  19.178  -27.233 1.00 31.49  ? 2   VAL H CG2 1 
ATOM   1569 N N   . GLN B 2 3   ? -12.084 20.490  -26.310 1.00 28.97  ? 3   GLN H N   1 
ATOM   1570 C CA  . GLN B 2 3   ? -13.314 20.555  -25.537 1.00 39.03  ? 3   GLN H CA  1 
ATOM   1571 C C   . GLN B 2 3   ? -13.929 19.166  -25.443 1.00 30.18  ? 3   GLN H C   1 
ATOM   1572 O O   . GLN B 2 3   ? -13.841 18.366  -26.379 1.00 36.50  ? 3   GLN H O   1 
ATOM   1573 C CB  . GLN B 2 3   ? -14.321 21.537  -26.153 1.00 33.75  ? 3   GLN H CB  1 
ATOM   1574 C CG  . GLN B 2 3   ? -13.811 22.966  -26.239 1.00 52.70  ? 3   GLN H CG  1 
ATOM   1575 C CD  . GLN B 2 3   ? -14.926 23.989  -26.154 1.00 61.56  ? 3   GLN H CD  1 
ATOM   1576 O OE1 . GLN B 2 3   ? -15.319 24.403  -25.063 1.00 63.72  ? 3   GLN H OE1 1 
ATOM   1577 N NE2 . GLN B 2 3   ? -15.441 24.404  -27.306 1.00 64.81  ? 3   GLN H NE2 1 
ATOM   1578 N N   . LEU B 2 4   ? -14.552 18.888  -24.300 1.00 30.78  ? 4   LEU H N   1 
ATOM   1579 C CA  . LEU B 2 4   ? -15.157 17.593  -24.018 1.00 28.93  ? 4   LEU H CA  1 
ATOM   1580 C C   . LEU B 2 4   ? -16.659 17.761  -23.849 1.00 23.36  ? 4   LEU H C   1 
ATOM   1581 O O   . LEU B 2 4   ? -17.109 18.638  -23.105 1.00 29.05  ? 4   LEU H O   1 
ATOM   1582 C CB  . LEU B 2 4   ? -14.549 16.966  -22.759 1.00 21.26  ? 4   LEU H CB  1 
ATOM   1583 C CG  . LEU B 2 4   ? -13.067 16.596  -22.831 1.00 25.06  ? 4   LEU H CG  1 
ATOM   1584 C CD1 . LEU B 2 4   ? -12.550 16.184  -21.463 1.00 28.53  ? 4   LEU H CD1 1 
ATOM   1585 C CD2 . LEU B 2 4   ? -12.848 15.484  -23.845 1.00 22.84  ? 4   LEU H CD2 1 
ATOM   1586 N N   . VAL B 2 5   ? -17.429 16.919  -24.536 1.00 23.23  ? 5   VAL H N   1 
ATOM   1587 C CA  . VAL B 2 5   ? -18.886 16.950  -24.486 1.00 29.56  ? 5   VAL H CA  1 
ATOM   1588 C C   . VAL B 2 5   ? -19.374 15.603  -23.974 1.00 26.23  ? 5   VAL H C   1 
ATOM   1589 O O   . VAL B 2 5   ? -19.027 14.557  -24.536 1.00 21.59  ? 5   VAL H O   1 
ATOM   1590 C CB  . VAL B 2 5   ? -19.496 17.266  -25.864 1.00 27.11  ? 5   VAL H CB  1 
ATOM   1591 C CG1 . VAL B 2 5   ? -21.014 17.205  -25.799 1.00 25.88  ? 5   VAL H CG1 1 
ATOM   1592 C CG2 . VAL B 2 5   ? -19.033 18.633  -26.346 1.00 14.96  ? 5   VAL H CG2 1 
ATOM   1593 N N   . GLN B 2 6   ? -20.178 15.628  -22.916 1.00 26.00  ? 6   GLN H N   1 
ATOM   1594 C CA  . GLN B 2 6   ? -20.664 14.415  -22.278 1.00 24.69  ? 6   GLN H CA  1 
ATOM   1595 C C   . GLN B 2 6   ? -22.125 14.162  -22.632 1.00 24.02  ? 6   GLN H C   1 
ATOM   1596 O O   . GLN B 2 6   ? -22.844 15.052  -23.094 1.00 36.47  ? 6   GLN H O   1 
ATOM   1597 C CB  . GLN B 2 6   ? -20.507 14.497  -20.758 1.00 28.75  ? 6   GLN H CB  1 
ATOM   1598 C CG  . GLN B 2 6   ? -19.119 14.900  -20.297 1.00 29.38  ? 6   GLN H CG  1 
ATOM   1599 C CD  . GLN B 2 6   ? -18.808 14.417  -18.893 1.00 26.70  ? 6   GLN H CD  1 
ATOM   1600 O OE1 . GLN B 2 6   ? -18.062 15.059  -18.153 1.00 18.75  ? 6   GLN H OE1 1 
ATOM   1601 N NE2 . GLN B 2 6   ? -19.372 13.273  -18.523 1.00 30.92  ? 6   GLN H NE2 1 
ATOM   1602 N N   . SER B 2 7   ? -22.555 12.925  -22.403 1.00 29.11  ? 7   SER H N   1 
ATOM   1603 C CA  . SER B 2 7   ? -23.930 12.540  -22.670 1.00 22.34  ? 7   SER H CA  1 
ATOM   1604 C C   . SER B 2 7   ? -24.860 13.109  -21.598 1.00 23.06  ? 7   SER H C   1 
ATOM   1605 O O   . SER B 2 7   ? -24.426 13.642  -20.572 1.00 28.31  ? 7   SER H O   1 
ATOM   1606 C CB  . SER B 2 7   ? -24.055 11.018  -22.741 1.00 23.41  ? 7   SER H CB  1 
ATOM   1607 O OG  . SER B 2 7   ? -23.576 10.410  -21.554 1.00 35.08  ? 7   SER H OG  1 
ATOM   1608 N N   . GLY B 2 8   ? -26.163 12.986  -21.850 1.00 33.17  ? 8   GLY H N   1 
ATOM   1609 C CA  . GLY B 2 8   ? -27.155 13.574  -20.977 1.00 26.92  ? 8   GLY H CA  1 
ATOM   1610 C C   . GLY B 2 8   ? -27.359 12.800  -19.688 1.00 34.74  ? 8   GLY H C   1 
ATOM   1611 O O   . GLY B 2 8   ? -26.829 11.708  -19.487 1.00 35.27  ? 8   GLY H O   1 
ATOM   1612 N N   . ALA B 2 9   ? -28.155 13.397  -18.803 1.00 35.67  ? 9   ALA H N   1 
ATOM   1613 C CA  . ALA B 2 9   ? -28.417 12.804  -17.499 1.00 29.99  ? 9   ALA H CA  1 
ATOM   1614 C C   . ALA B 2 9   ? -29.169 11.486  -17.643 1.00 34.75  ? 9   ALA H C   1 
ATOM   1615 O O   . ALA B 2 9   ? -29.998 11.309  -18.540 1.00 35.24  ? 9   ALA H O   1 
ATOM   1616 C CB  . ALA B 2 9   ? -29.214 13.773  -16.625 1.00 23.77  ? 9   ALA H CB  1 
ATOM   1617 N N   . GLU B 2 10  ? -28.871 10.553  -16.742 1.00 38.06  ? 10  GLU H N   1 
ATOM   1618 C CA  . GLU B 2 10  ? -29.419 9.205   -16.782 1.00 35.67  ? 10  GLU H CA  1 
ATOM   1619 C C   . GLU B 2 10  ? -30.148 8.904   -15.481 1.00 32.46  ? 10  GLU H C   1 
ATOM   1620 O O   . GLU B 2 10  ? -29.626 9.174   -14.394 1.00 33.07  ? 10  GLU H O   1 
ATOM   1621 C CB  . GLU B 2 10  ? -28.310 8.174   -17.015 1.00 40.17  ? 10  GLU H CB  1 
ATOM   1622 C CG  . GLU B 2 10  ? -27.572 8.339   -18.334 1.00 40.21  ? 10  GLU H CG  1 
ATOM   1623 C CD  . GLU B 2 10  ? -28.329 7.741   -19.504 1.00 47.84  ? 10  GLU H CD  1 
ATOM   1624 O OE1 . GLU B 2 10  ? -29.278 6.965   -19.266 1.00 51.20  ? 10  GLU H OE1 1 
ATOM   1625 O OE2 . GLU B 2 10  ? -27.972 8.045   -20.662 1.00 52.49  ? 10  GLU H OE2 1 
ATOM   1626 N N   . VAL B 2 11  ? -31.353 8.349   -15.596 1.00 31.12  ? 11  VAL H N   1 
ATOM   1627 C CA  . VAL B 2 11  ? -32.124 7.861   -14.457 1.00 31.85  ? 11  VAL H CA  1 
ATOM   1628 C C   . VAL B 2 11  ? -32.438 6.395   -14.718 1.00 38.44  ? 11  VAL H C   1 
ATOM   1629 O O   . VAL B 2 11  ? -33.137 6.069   -15.685 1.00 44.66  ? 11  VAL H O   1 
ATOM   1630 C CB  . VAL B 2 11  ? -33.412 8.671   -14.243 1.00 33.39  ? 11  VAL H CB  1 
ATOM   1631 C CG1 . VAL B 2 11  ? -34.140 8.188   -12.997 1.00 25.24  ? 11  VAL H CG1 1 
ATOM   1632 C CG2 . VAL B 2 11  ? -33.097 10.156  -14.145 1.00 23.26  ? 11  VAL H CG2 1 
ATOM   1633 N N   . LYS B 2 12  ? -31.926 5.515   -13.860 1.00 32.33  ? 12  LYS H N   1 
ATOM   1634 C CA  . LYS B 2 12  ? -32.005 4.080   -14.084 1.00 34.20  ? 12  LYS H CA  1 
ATOM   1635 C C   . LYS B 2 12  ? -32.475 3.369   -12.824 1.00 34.05  ? 12  LYS H C   1 
ATOM   1636 O O   . LYS B 2 12  ? -32.260 3.840   -11.705 1.00 33.23  ? 12  LYS H O   1 
ATOM   1637 C CB  . LYS B 2 12  ? -30.645 3.507   -14.514 1.00 37.67  ? 12  LYS H CB  1 
ATOM   1638 C CG  . LYS B 2 12  ? -29.950 4.284   -15.623 1.00 28.90  ? 12  LYS H CG  1 
ATOM   1639 C CD  . LYS B 2 12  ? -30.653 4.116   -16.961 1.00 30.96  ? 12  LYS H CD  1 
ATOM   1640 C CE  . LYS B 2 12  ? -30.497 2.701   -17.494 1.00 28.66  ? 12  LYS H CE  1 
ATOM   1641 N NZ  . LYS B 2 12  ? -31.040 2.561   -18.872 1.00 33.88  ? 12  LYS H NZ  1 
ATOM   1642 N N   . LYS B 2 13  ? -33.131 2.229   -13.023 1.00 30.16  ? 13  LYS H N   1 
ATOM   1643 C CA  . LYS B 2 13  ? -33.476 1.337   -11.930 1.00 32.31  ? 13  LYS H CA  1 
ATOM   1644 C C   . LYS B 2 13  ? -32.273 0.468   -11.566 1.00 34.82  ? 13  LYS H C   1 
ATOM   1645 O O   . LYS B 2 13  ? -31.403 0.223   -12.407 1.00 30.81  ? 13  LYS H O   1 
ATOM   1646 C CB  . LYS B 2 13  ? -34.656 0.451   -12.319 1.00 40.10  ? 13  LYS H CB  1 
ATOM   1647 C CG  . LYS B 2 13  ? -35.938 1.211   -12.623 1.00 34.08  ? 13  LYS H CG  1 
ATOM   1648 C CD  . LYS B 2 13  ? -36.602 1.717   -11.352 1.00 49.31  ? 13  LYS H CD  1 
ATOM   1649 C CE  . LYS B 2 13  ? -37.737 2.681   -11.667 1.00 40.73  ? 13  LYS H CE  1 
ATOM   1650 N NZ  . LYS B 2 13  ? -38.756 2.089   -12.576 1.00 37.09  ? 13  LYS H NZ  1 
ATOM   1651 N N   . PRO B 2 14  ? -32.190 0.005   -10.319 1.00 35.06  ? 14  PRO H N   1 
ATOM   1652 C CA  . PRO B 2 14  ? -31.088 -0.890  -9.944  1.00 32.57  ? 14  PRO H CA  1 
ATOM   1653 C C   . PRO B 2 14  ? -31.113 -2.169  -10.767 1.00 33.77  ? 14  PRO H C   1 
ATOM   1654 O O   . PRO B 2 14  ? -32.174 -2.727  -11.053 1.00 38.39  ? 14  PRO H O   1 
ATOM   1655 C CB  . PRO B 2 14  ? -31.346 -1.169  -8.459  1.00 32.53  ? 14  PRO H CB  1 
ATOM   1656 C CG  . PRO B 2 14  ? -32.168 -0.014  -7.994  1.00 35.08  ? 14  PRO H CG  1 
ATOM   1657 C CD  . PRO B 2 14  ? -33.034 0.350   -9.163  1.00 35.88  ? 14  PRO H CD  1 
ATOM   1658 N N   . GLY B 2 15  ? -29.922 -2.632  -11.146 1.00 35.29  ? 15  GLY H N   1 
ATOM   1659 C CA  . GLY B 2 15  ? -29.772 -3.818  -11.955 1.00 26.94  ? 15  GLY H CA  1 
ATOM   1660 C C   . GLY B 2 15  ? -29.679 -3.569  -13.446 1.00 34.93  ? 15  GLY H C   1 
ATOM   1661 O O   . GLY B 2 15  ? -29.219 -4.452  -14.179 1.00 35.58  ? 15  GLY H O   1 
ATOM   1662 N N   . GLU B 2 16  ? -30.102 -2.400  -13.917 1.00 32.52  ? 16  GLU H N   1 
ATOM   1663 C CA  . GLU B 2 16  ? -30.013 -2.073  -15.331 1.00 37.39  ? 16  GLU H CA  1 
ATOM   1664 C C   . GLU B 2 16  ? -28.585 -1.698  -15.710 1.00 43.57  ? 16  GLU H C   1 
ATOM   1665 O O   . GLU B 2 16  ? -27.799 -1.233  -14.880 1.00 41.93  ? 16  GLU H O   1 
ATOM   1666 C CB  . GLU B 2 16  ? -30.960 -0.924  -15.679 1.00 31.00  ? 16  GLU H CB  1 
ATOM   1667 C CG  . GLU B 2 16  ? -32.433 -1.253  -15.500 1.00 31.99  ? 16  GLU H CG  1 
ATOM   1668 C CD  . GLU B 2 16  ? -33.335 -0.070  -15.795 1.00 38.96  ? 16  GLU H CD  1 
ATOM   1669 O OE1 . GLU B 2 16  ? -32.822 1.065   -15.881 1.00 50.79  ? 16  GLU H OE1 1 
ATOM   1670 O OE2 . GLU B 2 16  ? -34.559 -0.275  -15.942 1.00 53.19  ? 16  GLU H OE2 1 
ATOM   1671 N N   . SER B 2 17  ? -28.253 -1.911  -16.978 1.00 38.52  ? 17  SER H N   1 
ATOM   1672 C CA  . SER B 2 17  ? -26.960 -1.505  -17.504 1.00 35.23  ? 17  SER H CA  1 
ATOM   1673 C C   . SER B 2 17  ? -27.004 -0.045  -17.944 1.00 35.39  ? 17  SER H C   1 
ATOM   1674 O O   . SER B 2 17  ? -28.071 0.543   -18.135 1.00 30.13  ? 17  SER H O   1 
ATOM   1675 C CB  . SER B 2 17  ? -26.544 -2.397  -18.674 1.00 34.03  ? 17  SER H CB  1 
ATOM   1676 O OG  . SER B 2 17  ? -27.457 -2.284  -19.750 1.00 34.17  ? 17  SER H OG  1 
ATOM   1677 N N   . LEU B 2 18  ? -25.819 0.537   -18.103 1.00 29.56  ? 18  LEU H N   1 
ATOM   1678 C CA  . LEU B 2 18  ? -25.704 1.933   -18.498 1.00 28.80  ? 18  LEU H CA  1 
ATOM   1679 C C   . LEU B 2 18  ? -24.347 2.150   -19.144 1.00 32.88  ? 18  LEU H C   1 
ATOM   1680 O O   . LEU B 2 18  ? -23.350 1.586   -18.693 1.00 30.95  ? 18  LEU H O   1 
ATOM   1681 C CB  . LEU B 2 18  ? -25.871 2.866   -17.293 1.00 27.43  ? 18  LEU H CB  1 
ATOM   1682 C CG  . LEU B 2 18  ? -25.612 4.352   -17.547 1.00 34.31  ? 18  LEU H CG  1 
ATOM   1683 C CD1 . LEU B 2 18  ? -26.584 4.881   -18.585 1.00 32.41  ? 18  LEU H CD1 1 
ATOM   1684 C CD2 . LEU B 2 18  ? -25.714 5.145   -16.257 1.00 25.36  ? 18  LEU H CD2 1 
ATOM   1685 N N   . LYS B 2 19  ? -24.318 2.963   -20.200 1.00 31.67  ? 19  LYS H N   1 
ATOM   1686 C CA  . LYS B 2 19  ? -23.073 3.370   -20.842 1.00 23.48  ? 19  LYS H CA  1 
ATOM   1687 C C   . LYS B 2 19  ? -23.161 4.852   -21.165 1.00 29.94  ? 19  LYS H C   1 
ATOM   1688 O O   . LYS B 2 19  ? -24.007 5.263   -21.964 1.00 32.65  ? 19  LYS H O   1 
ATOM   1689 C CB  . LYS B 2 19  ? -22.804 2.561   -22.116 1.00 26.41  ? 19  LYS H CB  1 
ATOM   1690 C CG  . LYS B 2 19  ? -21.549 2.998   -22.863 1.00 37.34  ? 19  LYS H CG  1 
ATOM   1691 C CD  . LYS B 2 19  ? -21.407 2.294   -24.205 1.00 40.37  ? 19  LYS H CD  1 
ATOM   1692 C CE  . LYS B 2 19  ? -21.114 0.813   -24.037 1.00 57.49  ? 19  LYS H CE  1 
ATOM   1693 N NZ  . LYS B 2 19  ? -20.892 0.143   -25.349 1.00 49.36  ? 19  LYS H NZ  1 
ATOM   1694 N N   . ILE B 2 20  ? -22.292 5.649   -20.551 1.00 34.96  ? 20  ILE H N   1 
ATOM   1695 C CA  . ILE B 2 20  ? -22.230 7.079   -20.816 1.00 29.09  ? 20  ILE H CA  1 
ATOM   1696 C C   . ILE B 2 20  ? -21.008 7.361   -21.682 1.00 29.74  ? 20  ILE H C   1 
ATOM   1697 O O   . ILE B 2 20  ? -20.055 6.577   -21.737 1.00 32.96  ? 20  ILE H O   1 
ATOM   1698 C CB  . ILE B 2 20  ? -22.199 7.911   -19.518 1.00 25.20  ? 20  ILE H CB  1 
ATOM   1699 C CG1 . ILE B 2 20  ? -20.958 7.574   -18.691 1.00 32.06  ? 20  ILE H CG1 1 
ATOM   1700 C CG2 . ILE B 2 20  ? -23.461 7.667   -18.706 1.00 25.49  ? 20  ILE H CG2 1 
ATOM   1701 C CD1 . ILE B 2 20  ? -20.856 8.366   -17.406 1.00 23.96  ? 20  ILE H CD1 1 
ATOM   1702 N N   . SER B 2 21  ? -21.041 8.503   -22.366 1.00 25.56  ? 21  SER H N   1 
ATOM   1703 C CA  . SER B 2 21  ? -20.065 8.816   -23.398 1.00 20.82  ? 21  SER H CA  1 
ATOM   1704 C C   . SER B 2 21  ? -19.468 10.200  -23.177 1.00 27.92  ? 21  SER H C   1 
ATOM   1705 O O   . SER B 2 21  ? -20.060 11.067  -22.529 1.00 28.85  ? 21  SER H O   1 
ATOM   1706 C CB  . SER B 2 21  ? -20.691 8.746   -24.797 1.00 29.86  ? 21  SER H CB  1 
ATOM   1707 O OG  . SER B 2 21  ? -21.755 9.673   -24.923 1.00 35.35  ? 21  SER H OG  1 
ATOM   1708 N N   . CYS B 2 22  ? -18.275 10.388  -23.741 1.00 20.00  ? 22  CYS H N   1 
ATOM   1709 C CA  . CYS B 2 22  ? -17.543 11.649  -23.658 1.00 30.79  ? 22  CYS H CA  1 
ATOM   1710 C C   . CYS B 2 22  ? -16.798 11.826  -24.974 1.00 36.12  ? 22  CYS H C   1 
ATOM   1711 O O   . CYS B 2 22  ? -15.825 11.111  -25.232 1.00 43.31  ? 22  CYS H O   1 
ATOM   1712 C CB  . CYS B 2 22  ? -16.581 11.643  -22.471 1.00 25.55  ? 22  CYS H CB  1 
ATOM   1713 S SG  . CYS B 2 22  ? -15.438 13.044  -22.348 1.00 38.23  ? 22  CYS H SG  1 
ATOM   1714 N N   . LYS B 2 23  ? -17.250 12.763  -25.802 1.00 25.19  ? 23  LYS H N   1 
ATOM   1715 C CA  . LYS B 2 23  ? -16.665 13.007  -27.115 1.00 33.47  ? 23  LYS H CA  1 
ATOM   1716 C C   . LYS B 2 23  ? -15.846 14.289  -27.079 1.00 31.96  ? 23  LYS H C   1 
ATOM   1717 O O   . LYS B 2 23  ? -16.317 15.320  -26.585 1.00 32.62  ? 23  LYS H O   1 
ATOM   1718 C CB  . LYS B 2 23  ? -17.747 13.098  -28.193 1.00 32.23  ? 23  LYS H CB  1 
ATOM   1719 C CG  . LYS B 2 23  ? -17.202 13.352  -29.590 1.00 35.00  ? 23  LYS H CG  1 
ATOM   1720 C CD  . LYS B 2 23  ? -18.302 13.320  -30.637 1.00 30.62  ? 23  LYS H CD  1 
ATOM   1721 C CE  . LYS B 2 23  ? -17.749 13.646  -32.016 1.00 36.43  ? 23  LYS H CE  1 
ATOM   1722 N NZ  . LYS B 2 23  ? -18.791 13.562  -33.076 1.00 50.18  ? 23  LYS H NZ  1 
ATOM   1723 N N   . GLY B 2 24  ? -14.625 14.224  -27.604 1.00 33.29  ? 24  GLY H N   1 
ATOM   1724 C CA  . GLY B 2 24  ? -13.705 15.346  -27.588 1.00 31.25  ? 24  GLY H CA  1 
ATOM   1725 C C   . GLY B 2 24  ? -13.451 15.882  -28.984 1.00 33.96  ? 24  GLY H C   1 
ATOM   1726 O O   . GLY B 2 24  ? -13.519 15.145  -29.970 1.00 26.74  ? 24  GLY H O   1 
ATOM   1727 N N   . SER B 2 25  ? -13.152 17.177  -29.060 1.00 33.38  ? 25  SER H N   1 
ATOM   1728 C CA  . SER B 2 25  ? -12.876 17.833  -30.327 1.00 31.80  ? 25  SER H CA  1 
ATOM   1729 C C   . SER B 2 25  ? -11.848 18.930  -30.100 1.00 35.89  ? 25  SER H C   1 
ATOM   1730 O O   . SER B 2 25  ? -11.616 19.367  -28.969 1.00 32.00  ? 25  SER H O   1 
ATOM   1731 C CB  . SER B 2 25  ? -14.149 18.418  -30.952 1.00 27.72  ? 25  SER H CB  1 
ATOM   1732 O OG  . SER B 2 25  ? -14.604 19.542  -30.219 1.00 28.32  ? 25  SER H OG  1 
ATOM   1733 N N   . GLY B 2 26  ? -11.234 19.370  -31.188 1.00 34.67  ? 26  GLY H N   1 
ATOM   1734 C CA  . GLY B 2 26  ? -10.275 20.454  -31.156 1.00 33.67  ? 26  GLY H CA  1 
ATOM   1735 C C   . GLY B 2 26  ? -8.879  19.996  -31.538 1.00 45.25  ? 26  GLY H C   1 
ATOM   1736 O O   . GLY B 2 26  ? -8.576  18.807  -31.622 1.00 28.54  ? 26  GLY H O   1 
ATOM   1737 N N   . TYR B 2 27  ? -8.027  20.990  -31.774 1.00 44.01  ? 27  TYR H N   1 
ATOM   1738 C CA  . TYR B 2 27  ? -6.638  20.728  -32.114 1.00 46.42  ? 27  TYR H CA  1 
ATOM   1739 C C   . TYR B 2 27  ? -5.902  20.107  -30.931 1.00 43.90  ? 27  TYR H C   1 
ATOM   1740 O O   . TYR B 2 27  ? -6.224  20.362  -29.767 1.00 44.08  ? 27  TYR H O   1 
ATOM   1741 C CB  . TYR B 2 27  ? -5.945  22.020  -32.550 1.00 43.78  ? 27  TYR H CB  1 
ATOM   1742 C CG  . TYR B 2 27  ? -6.377  22.515  -33.913 1.00 51.30  ? 27  TYR H CG  1 
ATOM   1743 C CD1 . TYR B 2 27  ? -6.734  23.843  -34.111 1.00 45.94  ? 27  TYR H CD1 1 
ATOM   1744 C CD2 . TYR B 2 27  ? -6.419  21.656  -35.005 1.00 52.33  ? 27  TYR H CD2 1 
ATOM   1745 C CE1 . TYR B 2 27  ? -7.128  24.301  -35.355 1.00 47.50  ? 27  TYR H CE1 1 
ATOM   1746 C CE2 . TYR B 2 27  ? -6.810  22.105  -36.253 1.00 47.23  ? 27  TYR H CE2 1 
ATOM   1747 C CZ  . TYR B 2 27  ? -7.163  23.428  -36.422 1.00 56.16  ? 27  TYR H CZ  1 
ATOM   1748 O OH  . TYR B 2 27  ? -7.553  23.878  -37.663 1.00 65.38  ? 27  TYR H OH  1 
ATOM   1749 N N   . SER B 2 28  ? -4.911  19.271  -31.250 1.00 37.66  ? 28  SER H N   1 
ATOM   1750 C CA  . SER B 2 28  ? -4.074  18.557  -30.287 1.00 31.77  ? 28  SER H CA  1 
ATOM   1751 C C   . SER B 2 28  ? -4.840  17.505  -29.498 1.00 29.82  ? 28  SER H C   1 
ATOM   1752 O O   . SER B 2 28  ? -4.373  17.062  -28.442 1.00 34.82  ? 28  SER H O   1 
ATOM   1753 C CB  . SER B 2 28  ? -3.377  19.515  -29.314 1.00 34.63  ? 28  SER H CB  1 
ATOM   1754 O OG  . SER B 2 28  ? -4.272  19.944  -28.303 1.00 31.24  ? 28  SER H OG  1 
ATOM   1755 N N   . PHE B 2 29  ? -6.011  17.086  -29.978 1.00 22.29  ? 29  PHE H N   1 
ATOM   1756 C CA  . PHE B 2 29  ? -6.736  16.017  -29.299 1.00 28.96  ? 29  PHE H CA  1 
ATOM   1757 C C   . PHE B 2 29  ? -6.025  14.676  -29.426 1.00 25.05  ? 29  PHE H C   1 
ATOM   1758 O O   . PHE B 2 29  ? -6.241  13.790  -28.592 1.00 27.61  ? 29  PHE H O   1 
ATOM   1759 C CB  . PHE B 2 29  ? -8.157  15.899  -29.846 1.00 20.40  ? 29  PHE H CB  1 
ATOM   1760 C CG  . PHE B 2 29  ? -8.999  14.891  -29.118 1.00 20.73  ? 29  PHE H CG  1 
ATOM   1761 C CD1 . PHE B 2 29  ? -9.555  15.199  -27.890 1.00 16.26  ? 29  PHE H CD1 1 
ATOM   1762 C CD2 . PHE B 2 29  ? -9.227  13.635  -29.658 1.00 25.13  ? 29  PHE H CD2 1 
ATOM   1763 C CE1 . PHE B 2 29  ? -10.326 14.275  -27.213 1.00 19.57  ? 29  PHE H CE1 1 
ATOM   1764 C CE2 . PHE B 2 29  ? -9.998  12.707  -28.983 1.00 23.06  ? 29  PHE H CE2 1 
ATOM   1765 C CZ  . PHE B 2 29  ? -10.549 13.028  -27.760 1.00 15.69  ? 29  PHE H CZ  1 
ATOM   1766 N N   . ILE B 2 30  ? -5.178  14.513  -30.445 1.00 19.49  ? 30  ILE H N   1 
ATOM   1767 C CA  . ILE B 2 30  ? -4.425  13.278  -30.605 1.00 22.51  ? 30  ILE H CA  1 
ATOM   1768 C C   . ILE B 2 30  ? -3.504  13.031  -29.415 1.00 23.01  ? 30  ILE H C   1 
ATOM   1769 O O   . ILE B 2 30  ? -3.087  11.893  -29.179 1.00 22.32  ? 30  ILE H O   1 
ATOM   1770 C CB  . ILE B 2 30  ? -3.636  13.315  -31.933 1.00 17.44  ? 30  ILE H CB  1 
ATOM   1771 C CG1 . ILE B 2 30  ? -3.125  11.921  -32.298 1.00 20.07  ? 30  ILE H CG1 1 
ATOM   1772 C CG2 . ILE B 2 30  ? -2.493  14.309  -31.848 1.00 18.90  ? 30  ILE H CG2 1 
ATOM   1773 C CD1 . ILE B 2 30  ? -4.231  10.945  -32.620 1.00 26.99  ? 30  ILE H CD1 1 
ATOM   1774 N N   . THR B 2 31  ? -3.182  14.074  -28.651 1.00 19.79  ? 31  THR H N   1 
ATOM   1775 C CA  . THR B 2 31  ? -2.295  13.974  -27.499 1.00 22.12  ? 31  THR H CA  1 
ATOM   1776 C C   . THR B 2 31  ? -3.038  13.744  -26.192 1.00 28.77  ? 31  THR H C   1 
ATOM   1777 O O   . THR B 2 31  ? -2.401  13.722  -25.132 1.00 30.97  ? 31  THR H O   1 
ATOM   1778 C CB  . THR B 2 31  ? -1.459  15.247  -27.363 1.00 22.36  ? 31  THR H CB  1 
ATOM   1779 O OG1 . THR B 2 31  ? -2.305  16.327  -26.947 1.00 20.00  ? 31  THR H OG1 1 
ATOM   1780 C CG2 . THR B 2 31  ? -0.820  15.605  -28.686 1.00 33.98  ? 31  THR H CG2 1 
ATOM   1781 N N   . TYR B 2 32  ? -4.355  13.575  -26.235 1.00 24.89  ? 32  TYR H N   1 
ATOM   1782 C CA  . TYR B 2 32  ? -5.179  13.627  -25.036 1.00 30.09  ? 32  TYR H CA  1 
ATOM   1783 C C   . TYR B 2 32  ? -5.593  12.236  -24.572 1.00 19.60  ? 32  TYR H C   1 
ATOM   1784 O O   . TYR B 2 32  ? -6.039  11.407  -25.374 1.00 12.74  ? 32  TYR H O   1 
ATOM   1785 C CB  . TYR B 2 32  ? -6.415  14.492  -25.277 1.00 20.99  ? 32  TYR H CB  1 
ATOM   1786 C CG  . TYR B 2 32  ? -6.249  15.887  -24.730 1.00 22.60  ? 32  TYR H CG  1 
ATOM   1787 C CD1 . TYR B 2 32  ? -5.541  16.848  -25.435 1.00 20.09  ? 32  TYR H CD1 1 
ATOM   1788 C CD2 . TYR B 2 32  ? -6.781  16.237  -23.497 1.00 11.16  ? 32  TYR H CD2 1 
ATOM   1789 C CE1 . TYR B 2 32  ? -5.376  18.118  -24.936 1.00 17.21  ? 32  TYR H CE1 1 
ATOM   1790 C CE2 . TYR B 2 32  ? -6.622  17.505  -22.989 1.00 19.29  ? 32  TYR H CE2 1 
ATOM   1791 C CZ  . TYR B 2 32  ? -5.920  18.442  -23.714 1.00 23.98  ? 32  TYR H CZ  1 
ATOM   1792 O OH  . TYR B 2 32  ? -5.760  19.710  -23.210 1.00 30.49  ? 32  TYR H OH  1 
ATOM   1793 N N   . TRP B 2 33  ? -5.436  11.997  -23.272 1.00 22.68  ? 33  TRP H N   1 
ATOM   1794 C CA  . TRP B 2 33  ? -5.983  10.837  -22.584 1.00 22.81  ? 33  TRP H CA  1 
ATOM   1795 C C   . TRP B 2 33  ? -7.282  11.244  -21.902 1.00 24.80  ? 33  TRP H C   1 
ATOM   1796 O O   . TRP B 2 33  ? -7.380  12.343  -21.349 1.00 26.81  ? 33  TRP H O   1 
ATOM   1797 C CB  . TRP B 2 33  ? -5.001  10.298  -21.540 1.00 25.45  ? 33  TRP H CB  1 
ATOM   1798 C CG  . TRP B 2 33  ? -3.710  9.793   -22.099 1.00 30.83  ? 33  TRP H CG  1 
ATOM   1799 C CD1 . TRP B 2 33  ? -2.785  10.511  -22.796 1.00 25.44  ? 33  TRP H CD1 1 
ATOM   1800 C CD2 . TRP B 2 33  ? -3.189  8.462   -21.991 1.00 35.45  ? 33  TRP H CD2 1 
ATOM   1801 N NE1 . TRP B 2 33  ? -1.725  9.709   -23.141 1.00 28.37  ? 33  TRP H NE1 1 
ATOM   1802 C CE2 . TRP B 2 33  ? -1.948  8.446   -22.658 1.00 28.89  ? 33  TRP H CE2 1 
ATOM   1803 C CE3 . TRP B 2 33  ? -3.654  7.283   -21.401 1.00 28.51  ? 33  TRP H CE3 1 
ATOM   1804 C CZ2 . TRP B 2 33  ? -1.166  7.298   -22.751 1.00 28.64  ? 33  TRP H CZ2 1 
ATOM   1805 C CZ3 . TRP B 2 33  ? -2.876  6.143   -21.495 1.00 24.51  ? 33  TRP H CZ3 1 
ATOM   1806 C CH2 . TRP B 2 33  ? -1.646  6.160   -22.164 1.00 30.96  ? 33  TRP H CH2 1 
ATOM   1807 N N   . ILE B 2 34  ? -8.275  10.364  -21.942 1.00 22.97  ? 34  ILE H N   1 
ATOM   1808 C CA  . ILE B 2 34  ? -9.583  10.640  -21.358 1.00 23.11  ? 34  ILE H CA  1 
ATOM   1809 C C   . ILE B 2 34  ? -9.699  9.854   -20.059 1.00 27.41  ? 34  ILE H C   1 
ATOM   1810 O O   . ILE B 2 34  ? -9.727  8.618   -20.067 1.00 23.03  ? 34  ILE H O   1 
ATOM   1811 C CB  . ILE B 2 34  ? -10.722 10.291  -22.324 1.00 30.67  ? 34  ILE H CB  1 
ATOM   1812 C CG1 . ILE B 2 34  ? -10.536 11.028  -23.651 1.00 26.67  ? 34  ILE H CG1 1 
ATOM   1813 C CG2 . ILE B 2 34  ? -12.064 10.648  -21.702 1.00 24.98  ? 34  ILE H CG2 1 
ATOM   1814 C CD1 . ILE B 2 34  ? -10.562 12.534  -23.519 1.00 26.68  ? 34  ILE H CD1 1 
ATOM   1815 N N   . GLY B 2 35  ? -9.769  10.574  -18.940 1.00 24.17  ? 35  GLY H N   1 
ATOM   1816 C CA  . GLY B 2 35  ? -9.982  9.969   -17.647 1.00 23.34  ? 35  GLY H CA  1 
ATOM   1817 C C   . GLY B 2 35  ? -11.400 10.189  -17.154 1.00 20.75  ? 35  GLY H C   1 
ATOM   1818 O O   . GLY B 2 35  ? -12.120 11.057  -17.641 1.00 28.28  ? 35  GLY H O   1 
ATOM   1819 N N   . TRP B 2 36  ? -11.798 9.381   -16.175 1.00 20.62  ? 36  TRP H N   1 
ATOM   1820 C CA  . TRP B 2 36  ? -13.128 9.454   -15.587 1.00 23.11  ? 36  TRP H CA  1 
ATOM   1821 C C   . TRP B 2 36  ? -13.008 9.717   -14.094 1.00 17.83  ? 36  TRP H C   1 
ATOM   1822 O O   . TRP B 2 36  ? -12.195 9.087   -13.409 1.00 20.53  ? 36  TRP H O   1 
ATOM   1823 C CB  . TRP B 2 36  ? -13.916 8.170   -15.846 1.00 20.20  ? 36  TRP H CB  1 
ATOM   1824 C CG  . TRP B 2 36  ? -14.338 8.013   -17.276 1.00 20.72  ? 36  TRP H CG  1 
ATOM   1825 C CD1 . TRP B 2 36  ? -13.702 7.294   -18.246 1.00 27.12  ? 36  TRP H CD1 1 
ATOM   1826 C CD2 . TRP B 2 36  ? -15.490 8.596   -17.901 1.00 22.17  ? 36  TRP H CD2 1 
ATOM   1827 N NE1 . TRP B 2 36  ? -14.388 7.388   -19.433 1.00 26.93  ? 36  TRP H NE1 1 
ATOM   1828 C CE2 . TRP B 2 36  ? -15.489 8.182   -19.248 1.00 29.40  ? 36  TRP H CE2 1 
ATOM   1829 C CE3 . TRP B 2 36  ? -16.523 9.424   -17.450 1.00 19.56  ? 36  TRP H CE3 1 
ATOM   1830 C CZ2 . TRP B 2 36  ? -16.480 8.569   -20.149 1.00 25.68  ? 36  TRP H CZ2 1 
ATOM   1831 C CZ3 . TRP B 2 36  ? -17.505 9.807   -18.346 1.00 22.88  ? 36  TRP H CZ3 1 
ATOM   1832 C CH2 . TRP B 2 36  ? -17.477 9.380   -19.680 1.00 28.47  ? 36  TRP H CH2 1 
ATOM   1833 N N   . VAL B 2 37  ? -13.815 10.653  -13.598 1.00 16.91  ? 37  VAL H N   1 
ATOM   1834 C CA  . VAL B 2 37  ? -13.798 11.068  -12.201 1.00 16.58  ? 37  VAL H CA  1 
ATOM   1835 C C   . VAL B 2 37  ? -15.218 10.989  -11.660 1.00 26.34  ? 37  VAL H C   1 
ATOM   1836 O O   . VAL B 2 37  ? -16.150 11.524  -12.272 1.00 21.33  ? 37  VAL H O   1 
ATOM   1837 C CB  . VAL B 2 37  ? -13.237 12.494  -12.037 1.00 14.19  ? 37  VAL H CB  1 
ATOM   1838 C CG1 . VAL B 2 37  ? -13.331 12.941  -10.587 1.00 17.15  ? 37  VAL H CG1 1 
ATOM   1839 C CG2 . VAL B 2 37  ? -11.799 12.562  -12.531 1.00 23.26  ? 37  VAL H CG2 1 
ATOM   1840 N N   . ARG B 2 38  ? -15.383 10.328  -10.518 1.00 22.80  ? 38  ARG H N   1 
ATOM   1841 C CA  . ARG B 2 38  ? -16.681 10.194  -9.875  1.00 21.04  ? 38  ARG H CA  1 
ATOM   1842 C C   . ARG B 2 38  ? -16.778 11.137  -8.683  1.00 19.73  ? 38  ARG H C   1 
ATOM   1843 O O   . ARG B 2 38  ? -15.823 11.286  -7.915  1.00 23.78  ? 38  ARG H O   1 
ATOM   1844 C CB  . ARG B 2 38  ? -16.928 8.757   -9.412  1.00 19.73  ? 38  ARG H CB  1 
ATOM   1845 C CG  . ARG B 2 38  ? -18.308 8.549   -8.795  1.00 23.96  ? 38  ARG H CG  1 
ATOM   1846 C CD  . ARG B 2 38  ? -18.518 7.123   -8.317  1.00 21.28  ? 38  ARG H CD  1 
ATOM   1847 N NE  . ARG B 2 38  ? -17.821 6.849   -7.067  1.00 28.16  ? 38  ARG H NE  1 
ATOM   1848 C CZ  . ARG B 2 38  ? -17.921 5.713   -6.390  1.00 30.20  ? 38  ARG H CZ  1 
ATOM   1849 N NH1 . ARG B 2 38  ? -18.686 4.721   -6.816  1.00 19.21  ? 38  ARG H NH1 1 
ATOM   1850 N NH2 . ARG B 2 38  ? -17.239 5.570   -5.257  1.00 25.95  ? 38  ARG H NH2 1 
ATOM   1851 N N   . GLN B 2 39  ? -17.939 11.773  -8.537  1.00 19.00  ? 39  GLN H N   1 
ATOM   1852 C CA  . GLN B 2 39  ? -18.217 12.641  -7.396  1.00 18.95  ? 39  GLN H CA  1 
ATOM   1853 C C   . GLN B 2 39  ? -19.628 12.344  -6.909  1.00 19.58  ? 39  GLN H C   1 
ATOM   1854 O O   . GLN B 2 39  ? -20.606 12.723  -7.561  1.00 19.15  ? 39  GLN H O   1 
ATOM   1855 C CB  . GLN B 2 39  ? -18.067 14.117  -7.766  1.00 19.24  ? 39  GLN H CB  1 
ATOM   1856 C CG  . GLN B 2 39  ? -18.248 15.064  -6.591  1.00 23.81  ? 39  GLN H CG  1 
ATOM   1857 C CD  . GLN B 2 39  ? -17.935 16.504  -6.945  1.00 26.21  ? 39  GLN H CD  1 
ATOM   1858 O OE1 . GLN B 2 39  ? -18.261 16.974  -8.036  1.00 24.70  ? 39  GLN H OE1 1 
ATOM   1859 N NE2 . GLN B 2 39  ? -17.292 17.211  -6.024  1.00 23.25  ? 39  GLN H NE2 1 
ATOM   1860 N N   . MET B 2 40  ? -19.732 11.657  -5.774  1.00 18.66  ? 40  MET H N   1 
ATOM   1861 C CA  . MET B 2 40  ? -21.024 11.405  -5.164  1.00 24.48  ? 40  MET H CA  1 
ATOM   1862 C C   . MET B 2 40  ? -21.563 12.692  -4.541  1.00 24.32  ? 40  MET H C   1 
ATOM   1863 O O   . MET B 2 40  ? -20.796 13.603  -4.221  1.00 24.15  ? 40  MET H O   1 
ATOM   1864 C CB  . MET B 2 40  ? -20.905 10.293  -4.124  1.00 21.77  ? 40  MET H CB  1 
ATOM   1865 C CG  . MET B 2 40  ? -20.749 8.911   -4.748  1.00 28.79  ? 40  MET H CG  1 
ATOM   1866 S SD  . MET B 2 40  ? -20.193 7.634   -3.604  1.00 49.04  ? 40  MET H SD  1 
ATOM   1867 C CE  . MET B 2 40  ? -21.631 7.449   -2.554  1.00 39.23  ? 40  MET H CE  1 
ATOM   1868 N N   . PRO B 2 41  ? -22.897 12.799  -4.382  1.00 30.48  ? 41  PRO H N   1 
ATOM   1869 C CA  . PRO B 2 41  ? -23.492 14.050  -3.883  1.00 27.94  ? 41  PRO H CA  1 
ATOM   1870 C C   . PRO B 2 41  ? -22.864 14.570  -2.598  1.00 34.31  ? 41  PRO H C   1 
ATOM   1871 O O   . PRO B 2 41  ? -22.905 13.905  -1.558  1.00 31.10  ? 41  PRO H O   1 
ATOM   1872 C CB  . PRO B 2 41  ? -24.961 13.667  -3.664  1.00 16.83  ? 41  PRO H CB  1 
ATOM   1873 C CG  . PRO B 2 41  ? -25.209 12.596  -4.666  1.00 27.23  ? 41  PRO H CG  1 
ATOM   1874 C CD  . PRO B 2 41  ? -23.927 11.816  -4.768  1.00 24.15  ? 41  PRO H CD  1 
ATOM   1875 N N   . GLY B 2 42  ? -22.273 15.762  -2.670  1.00 31.13  ? 42  GLY H N   1 
ATOM   1876 C CA  . GLY B 2 42  ? -21.697 16.405  -1.508  1.00 24.50  ? 42  GLY H CA  1 
ATOM   1877 C C   . GLY B 2 42  ? -20.339 15.895  -1.084  1.00 30.79  ? 42  GLY H C   1 
ATOM   1878 O O   . GLY B 2 42  ? -19.846 16.309  -0.028  1.00 40.44  ? 42  GLY H O   1 
ATOM   1879 N N   . LYS B 2 43  ? -19.715 15.018  -1.864  1.00 30.77  ? 43  LYS H N   1 
ATOM   1880 C CA  . LYS B 2 43  ? -18.437 14.421  -1.513  1.00 30.66  ? 43  LYS H CA  1 
ATOM   1881 C C   . LYS B 2 43  ? -17.348 14.895  -2.476  1.00 25.79  ? 43  LYS H C   1 
ATOM   1882 O O   . LYS B 2 43  ? -17.574 15.756  -3.334  1.00 29.21  ? 43  LYS H O   1 
ATOM   1883 C CB  . LYS B 2 43  ? -18.564 12.897  -1.490  1.00 32.89  ? 43  LYS H CB  1 
ATOM   1884 C CG  . LYS B 2 43  ? -19.554 12.396  -0.454  1.00 35.14  ? 43  LYS H CG  1 
ATOM   1885 C CD  . LYS B 2 43  ? -19.160 12.863  0.938   1.00 39.03  ? 43  LYS H CD  1 
ATOM   1886 C CE  . LYS B 2 43  ? -20.335 12.798  1.898   1.00 45.44  ? 43  LYS H CE  1 
ATOM   1887 N NZ  . LYS B 2 43  ? -21.413 13.750  1.508   1.00 50.59  ? 43  LYS H NZ  1 
ATOM   1888 N N   . GLY B 2 44  ? -16.151 14.329  -2.324  1.00 29.78  ? 44  GLY H N   1 
ATOM   1889 C CA  . GLY B 2 44  ? -14.996 14.745  -3.088  1.00 19.04  ? 44  GLY H CA  1 
ATOM   1890 C C   . GLY B 2 44  ? -14.888 14.035  -4.425  1.00 20.27  ? 44  GLY H C   1 
ATOM   1891 O O   . GLY B 2 44  ? -15.787 13.317  -4.864  1.00 26.06  ? 44  GLY H O   1 
ATOM   1892 N N   . LEU B 2 45  ? -13.749 14.248  -5.078  1.00 19.68  ? 45  LEU H N   1 
ATOM   1893 C CA  . LEU B 2 45  ? -13.492 13.690  -6.399  1.00 19.40  ? 45  LEU H CA  1 
ATOM   1894 C C   . LEU B 2 45  ? -12.724 12.380  -6.281  1.00 21.52  ? 45  LEU H C   1 
ATOM   1895 O O   . LEU B 2 45  ? -11.782 12.266  -5.492  1.00 25.51  ? 45  LEU H O   1 
ATOM   1896 C CB  . LEU B 2 45  ? -12.704 14.681  -7.256  1.00 22.34  ? 45  LEU H CB  1 
ATOM   1897 C CG  . LEU B 2 45  ? -13.365 16.037  -7.505  1.00 26.48  ? 45  LEU H CG  1 
ATOM   1898 C CD1 . LEU B 2 45  ? -12.349 17.032  -8.035  1.00 14.34  ? 45  LEU H CD1 1 
ATOM   1899 C CD2 . LEU B 2 45  ? -14.528 15.893  -8.474  1.00 18.41  ? 45  LEU H CD2 1 
ATOM   1900 N N   . GLU B 2 46  ? -13.135 11.390  -7.073  1.00 18.15  ? 46  GLU H N   1 
ATOM   1901 C CA  . GLU B 2 46  ? -12.519 10.069  -7.067  1.00 15.21  ? 46  GLU H CA  1 
ATOM   1902 C C   . GLU B 2 46  ? -12.074 9.724   -8.479  1.00 18.24  ? 46  GLU H C   1 
ATOM   1903 O O   . GLU B 2 46  ? -12.894 9.701   -9.402  1.00 17.47  ? 46  GLU H O   1 
ATOM   1904 C CB  . GLU B 2 46  ? -13.493 9.008   -6.549  1.00 20.80  ? 46  GLU H CB  1 
ATOM   1905 C CG  . GLU B 2 46  ? -14.033 9.267   -5.155  1.00 31.18  ? 46  GLU H CG  1 
ATOM   1906 C CD  . GLU B 2 46  ? -15.316 8.507   -4.887  1.00 40.92  ? 46  GLU H CD  1 
ATOM   1907 O OE1 . GLU B 2 46  ? -16.401 9.046   -5.195  1.00 30.50  ? 46  GLU H OE1 1 
ATOM   1908 O OE2 . GLU B 2 46  ? -15.237 7.364   -4.386  1.00 30.57  ? 46  GLU H OE2 1 
ATOM   1909 N N   . TRP B 2 47  ? -10.786 9.439   -8.645  1.00 22.94  ? 47  TRP H N   1 
ATOM   1910 C CA  . TRP B 2 47  ? -10.268 9.025   -9.941  1.00 16.61  ? 47  TRP H CA  1 
ATOM   1911 C C   . TRP B 2 47  ? -10.623 7.565   -10.190 1.00 18.45  ? 47  TRP H C   1 
ATOM   1912 O O   . TRP B 2 47  ? -10.326 6.694   -9.365  1.00 20.43  ? 47  TRP H O   1 
ATOM   1913 C CB  . TRP B 2 47  ? -8.755  9.231   -10.002 1.00 13.94  ? 47  TRP H CB  1 
ATOM   1914 C CG  . TRP B 2 47  ? -8.175  9.007   -11.363 1.00 23.33  ? 47  TRP H CG  1 
ATOM   1915 C CD1 . TRP B 2 47  ? -8.178  9.883   -12.409 1.00 25.99  ? 47  TRP H CD1 1 
ATOM   1916 C CD2 . TRP B 2 47  ? -7.500  7.832   -11.825 1.00 25.78  ? 47  TRP H CD2 1 
ATOM   1917 N NE1 . TRP B 2 47  ? -7.549  9.325   -13.495 1.00 25.33  ? 47  TRP H NE1 1 
ATOM   1918 C CE2 . TRP B 2 47  ? -7.123  8.067   -13.163 1.00 27.10  ? 47  TRP H CE2 1 
ATOM   1919 C CE3 . TRP B 2 47  ? -7.179  6.604   -11.239 1.00 16.44  ? 47  TRP H CE3 1 
ATOM   1920 C CZ2 . TRP B 2 47  ? -6.441  7.119   -13.923 1.00 33.81  ? 47  TRP H CZ2 1 
ATOM   1921 C CZ3 . TRP B 2 47  ? -6.503  5.665   -11.995 1.00 24.87  ? 47  TRP H CZ3 1 
ATOM   1922 C CH2 . TRP B 2 47  ? -6.141  5.927   -13.323 1.00 31.44  ? 47  TRP H CH2 1 
ATOM   1923 N N   . MET B 2 48  ? -11.262 7.299   -11.328 1.00 15.12  ? 48  MET H N   1 
ATOM   1924 C CA  . MET B 2 48  ? -11.720 5.961   -11.680 1.00 15.00  ? 48  MET H CA  1 
ATOM   1925 C C   . MET B 2 48  ? -10.797 5.252   -12.659 1.00 19.27  ? 48  MET H C   1 
ATOM   1926 O O   . MET B 2 48  ? -10.505 4.066   -12.483 1.00 22.55  ? 48  MET H O   1 
ATOM   1927 C CB  . MET B 2 48  ? -13.125 6.026   -12.284 1.00 17.10  ? 48  MET H CB  1 
ATOM   1928 C CG  . MET B 2 48  ? -14.160 6.699   -11.407 1.00 16.59  ? 48  MET H CG  1 
ATOM   1929 S SD  . MET B 2 48  ? -15.764 6.733   -12.225 1.00 20.87  ? 48  MET H SD  1 
ATOM   1930 C CE  . MET B 2 48  ? -15.944 5.003   -12.653 1.00 18.15  ? 48  MET H CE  1 
ATOM   1931 N N   . GLY B 2 49  ? -10.344 5.950   -13.691 1.00 22.63  ? 49  GLY H N   1 
ATOM   1932 C CA  . GLY B 2 49  ? -9.501  5.338   -14.699 1.00 20.81  ? 49  GLY H CA  1 
ATOM   1933 C C   . GLY B 2 49  ? -9.188  6.341   -15.784 1.00 32.94  ? 49  GLY H C   1 
ATOM   1934 O O   . GLY B 2 49  ? -9.580  7.510   -15.715 1.00 28.54  ? 49  GLY H O   1 
ATOM   1935 N N   . ILE B 2 50  ? -8.466  5.864   -16.798 1.00 24.86  ? 50  ILE H N   1 
ATOM   1936 C CA  . ILE B 2 50  ? -8.055  6.712   -17.909 1.00 22.85  ? 50  ILE H CA  1 
ATOM   1937 C C   . ILE B 2 50  ? -7.778  5.813   -19.103 1.00 28.94  ? 50  ILE H C   1 
ATOM   1938 O O   . ILE B 2 50  ? -7.419  4.643   -18.947 1.00 32.20  ? 50  ILE H O   1 
ATOM   1939 C CB  . ILE B 2 50  ? -6.827  7.577   -17.527 1.00 23.12  ? 50  ILE H CB  1 
ATOM   1940 C CG1 . ILE B 2 50  ? -6.591  8.672   -18.570 1.00 23.62  ? 50  ILE H CG1 1 
ATOM   1941 C CG2 . ILE B 2 50  ? -5.589  6.707   -17.352 1.00 24.31  ? 50  ILE H CG2 1 
ATOM   1942 C CD1 . ILE B 2 50  ? -5.902  9.898   -18.016 1.00 29.94  ? 50  ILE H CD1 1 
ATOM   1943 N N   . ILE B 2 51  ? -7.965  6.358   -20.303 1.00 25.84  ? 51  ILE H N   1 
ATOM   1944 C CA  . ILE B 2 51  ? -7.771  5.597   -21.531 1.00 25.16  ? 51  ILE H CA  1 
ATOM   1945 C C   . ILE B 2 51  ? -7.208  6.521   -22.602 1.00 20.62  ? 51  ILE H C   1 
ATOM   1946 O O   . ILE B 2 51  ? -7.542  7.708   -22.658 1.00 22.07  ? 51  ILE H O   1 
ATOM   1947 C CB  . ILE B 2 51  ? -9.086  4.932   -21.994 1.00 22.82  ? 51  ILE H CB  1 
ATOM   1948 C CG1 . ILE B 2 51  ? -8.833  4.024   -23.198 1.00 23.35  ? 51  ILE H CG1 1 
ATOM   1949 C CG2 . ILE B 2 51  ? -10.138 5.984   -22.323 1.00 17.67  ? 51  ILE H CG2 1 
ATOM   1950 C CD1 . ILE B 2 51  ? -10.049 3.259   -23.645 1.00 18.90  ? 51  ILE H CD1 1 
ATOM   1951 N N   . TYR B 2 52  ? -6.327  5.972   -23.440 1.00 27.87  ? 52  TYR H N   1 
ATOM   1952 C CA  . TYR B 2 52  ? -5.877  6.663   -24.638 1.00 27.25  ? 52  TYR H CA  1 
ATOM   1953 C C   . TYR B 2 52  ? -6.696  6.170   -25.818 1.00 26.25  ? 52  TYR H C   1 
ATOM   1954 O O   . TYR B 2 52  ? -6.626  4.975   -26.147 1.00 23.94  ? 52  TYR H O   1 
ATOM   1955 C CB  . TYR B 2 52  ? -4.393  6.422   -24.885 1.00 24.09  ? 52  TYR H CB  1 
ATOM   1956 C CG  . TYR B 2 52  ? -3.852  7.169   -26.085 1.00 31.56  ? 52  TYR H CG  1 
ATOM   1957 C CD1 . TYR B 2 52  ? -3.581  8.530   -26.016 1.00 23.52  ? 52  TYR H CD1 1 
ATOM   1958 C CD2 . TYR B 2 52  ? -3.615  6.514   -27.288 1.00 25.12  ? 52  TYR H CD2 1 
ATOM   1959 C CE1 . TYR B 2 52  ? -3.090  9.217   -27.109 1.00 24.68  ? 52  TYR H CE1 1 
ATOM   1960 C CE2 . TYR B 2 52  ? -3.122  7.193   -28.386 1.00 17.63  ? 52  TYR H CE2 1 
ATOM   1961 C CZ  . TYR B 2 52  ? -2.863  8.544   -28.291 1.00 32.78  ? 52  TYR H CZ  1 
ATOM   1962 O OH  . TYR B 2 52  ? -2.373  9.224   -29.383 1.00 32.39  ? 52  TYR H OH  1 
ATOM   1963 N N   . PRO B 2 53  A -7.480  7.031   -26.470 1.00 27.99  ? 52  PRO H N   1 
ATOM   1964 C CA  . PRO B 2 53  A -8.398  6.544   -27.515 1.00 23.48  ? 52  PRO H CA  1 
ATOM   1965 C C   . PRO B 2 53  A -7.708  5.866   -28.686 1.00 27.19  ? 52  PRO H C   1 
ATOM   1966 O O   . PRO B 2 53  A -8.325  5.017   -29.343 1.00 30.26  ? 52  PRO H O   1 
ATOM   1967 C CB  . PRO B 2 53  A -9.127  7.822   -27.958 1.00 25.65  ? 52  PRO H CB  1 
ATOM   1968 C CG  . PRO B 2 53  A -8.999  8.756   -26.797 1.00 19.76  ? 52  PRO H CG  1 
ATOM   1969 C CD  . PRO B 2 53  A -7.654  8.468   -26.203 1.00 23.70  ? 52  PRO H CD  1 
ATOM   1970 N N   . GLY B 2 54  ? -6.450  6.212   -28.970 1.00 32.35  ? 53  GLY H N   1 
ATOM   1971 C CA  . GLY B 2 54  ? -5.797  5.685   -30.159 1.00 30.33  ? 53  GLY H CA  1 
ATOM   1972 C C   . GLY B 2 54  ? -5.636  4.176   -30.132 1.00 34.88  ? 53  GLY H C   1 
ATOM   1973 O O   . GLY B 2 54  ? -5.931  3.490   -31.113 1.00 41.91  ? 53  GLY H O   1 
ATOM   1974 N N   . ASP B 2 55  ? -5.166  3.638   -29.006 1.00 31.29  ? 54  ASP H N   1 
ATOM   1975 C CA  . ASP B 2 55  ? -4.910  2.206   -28.889 1.00 34.59  ? 54  ASP H CA  1 
ATOM   1976 C C   . ASP B 2 55  ? -5.681  1.560   -27.746 1.00 28.87  ? 54  ASP H C   1 
ATOM   1977 O O   . ASP B 2 55  ? -5.382  0.415   -27.384 1.00 31.39  ? 54  ASP H O   1 
ATOM   1978 C CB  . ASP B 2 55  ? -3.409  1.944   -28.725 1.00 21.01  ? 54  ASP H CB  1 
ATOM   1979 C CG  . ASP B 2 55  ? -2.816  2.650   -27.518 1.00 35.08  ? 54  ASP H CG  1 
ATOM   1980 O OD1 . ASP B 2 55  ? -3.543  3.412   -26.846 1.00 28.68  ? 54  ASP H OD1 1 
ATOM   1981 O OD2 . ASP B 2 55  ? -1.617  2.441   -27.239 1.00 37.83  ? 54  ASP H OD2 1 
ATOM   1982 N N   . SER B 2 56  ? -6.659  2.261   -27.170 1.00 27.15  ? 55  SER H N   1 
ATOM   1983 C CA  . SER B 2 56  ? -7.457  1.755   -26.051 1.00 28.22  ? 55  SER H CA  1 
ATOM   1984 C C   . SER B 2 56  ? -6.583  1.337   -24.871 1.00 26.24  ? 55  SER H C   1 
ATOM   1985 O O   . SER B 2 56  ? -6.914  0.400   -24.140 1.00 36.44  ? 55  SER H O   1 
ATOM   1986 C CB  . SER B 2 56  ? -8.359  0.596   -26.486 1.00 23.87  ? 55  SER H CB  1 
ATOM   1987 O OG  . SER B 2 56  ? -9.402  1.051   -27.331 1.00 29.89  ? 55  SER H OG  1 
ATOM   1988 N N   . ASP B 2 57  ? -5.461  2.027   -24.678 1.00 29.47  ? 56  ASP H N   1 
ATOM   1989 C CA  . ASP B 2 57  ? -4.600  1.786   -23.525 1.00 31.46  ? 56  ASP H CA  1 
ATOM   1990 C C   . ASP B 2 57  ? -5.319  2.269   -22.272 1.00 28.07  ? 56  ASP H C   1 
ATOM   1991 O O   . ASP B 2 57  ? -5.413  3.476   -22.028 1.00 18.66  ? 56  ASP H O   1 
ATOM   1992 C CB  . ASP B 2 57  ? -3.263  2.500   -23.707 1.00 27.08  ? 56  ASP H CB  1 
ATOM   1993 C CG  . ASP B 2 57  ? -2.253  2.142   -22.633 1.00 32.55  ? 56  ASP H CG  1 
ATOM   1994 O OD1 . ASP B 2 57  ? -2.537  1.242   -21.814 1.00 39.00  ? 56  ASP H OD1 1 
ATOM   1995 O OD2 . ASP B 2 57  ? -1.170  2.765   -22.605 1.00 35.81  ? 56  ASP H OD2 1 
ATOM   1996 N N   . THR B 2 58  ? -5.824  1.332   -21.475 1.00 31.52  ? 57  THR H N   1 
ATOM   1997 C CA  . THR B 2 58  ? -6.699  1.638   -20.352 1.00 27.62  ? 57  THR H CA  1 
ATOM   1998 C C   . THR B 2 58  ? -6.015  1.280   -19.040 1.00 33.59  ? 57  THR H C   1 
ATOM   1999 O O   . THR B 2 58  ? -5.453  0.188   -18.905 1.00 37.56  ? 57  THR H O   1 
ATOM   2000 C CB  . THR B 2 58  ? -8.023  0.880   -20.470 1.00 27.98  ? 57  THR H CB  1 
ATOM   2001 O OG1 . THR B 2 58  ? -8.531  1.008   -21.803 1.00 38.85  ? 57  THR H OG1 1 
ATOM   2002 C CG2 . THR B 2 58  ? -9.042  1.441   -19.491 1.00 30.52  ? 57  THR H CG2 1 
ATOM   2003 N N   . ARG B 2 59  ? -6.069  2.200   -18.081 1.00 25.29  ? 58  ARG H N   1 
ATOM   2004 C CA  . ARG B 2 59  ? -5.576  1.973   -16.730 1.00 30.01  ? 58  ARG H CA  1 
ATOM   2005 C C   . ARG B 2 59  ? -6.696  2.271   -15.746 1.00 29.67  ? 58  ARG H C   1 
ATOM   2006 O O   . ARG B 2 59  ? -7.308  3.342   -15.805 1.00 31.91  ? 58  ARG H O   1 
ATOM   2007 C CB  . ARG B 2 59  ? -4.354  2.844   -16.433 1.00 25.79  ? 58  ARG H CB  1 
ATOM   2008 C CG  . ARG B 2 59  ? -3.248  2.715   -17.465 1.00 32.73  ? 58  ARG H CG  1 
ATOM   2009 C CD  . ARG B 2 59  ? -1.976  3.417   -17.026 1.00 42.16  ? 58  ARG H CD  1 
ATOM   2010 N NE  . ARG B 2 59  ? -0.964  3.389   -18.075 1.00 36.53  ? 58  ARG H NE  1 
ATOM   2011 C CZ  . ARG B 2 59  ? 0.281   3.824   -17.932 1.00 34.25  ? 58  ARG H CZ  1 
ATOM   2012 N NH1 . ARG B 2 59  ? 0.711   4.323   -16.785 1.00 42.69  ? 58  ARG H NH1 1 
ATOM   2013 N NH2 . ARG B 2 59  ? 1.115   3.753   -18.965 1.00 50.88  ? 58  ARG H NH2 1 
ATOM   2014 N N   . TYR B 2 60  ? -6.959  1.329   -14.846 1.00 26.73  ? 59  TYR H N   1 
ATOM   2015 C CA  . TYR B 2 60  ? -8.050  1.434   -13.892 1.00 28.15  ? 59  TYR H CA  1 
ATOM   2016 C C   . TYR B 2 60  ? -7.520  1.716   -12.493 1.00 28.20  ? 59  TYR H C   1 
ATOM   2017 O O   . TYR B 2 60  ? -6.428  1.275   -12.121 1.00 28.00  ? 59  TYR H O   1 
ATOM   2018 C CB  . TYR B 2 60  ? -8.884  0.150   -13.855 1.00 20.91  ? 59  TYR H CB  1 
ATOM   2019 C CG  . TYR B 2 60  ? -9.725  -0.103  -15.082 1.00 22.11  ? 59  TYR H CG  1 
ATOM   2020 C CD1 . TYR B 2 60  ? -11.000 0.438   -15.195 1.00 14.32  ? 59  TYR H CD1 1 
ATOM   2021 C CD2 . TYR B 2 60  ? -9.255  -0.899  -16.117 1.00 13.22  ? 59  TYR H CD2 1 
ATOM   2022 C CE1 . TYR B 2 60  ? -11.779 0.203   -16.313 1.00 18.21  ? 59  TYR H CE1 1 
ATOM   2023 C CE2 . TYR B 2 60  ? -10.025 -1.141  -17.238 1.00 19.25  ? 59  TYR H CE2 1 
ATOM   2024 C CZ  . TYR B 2 60  ? -11.286 -0.587  -17.331 1.00 23.81  ? 59  TYR H CZ  1 
ATOM   2025 O OH  . TYR B 2 60  ? -12.058 -0.825  -18.445 1.00 22.55  ? 59  TYR H OH  1 
ATOM   2026 N N   . SER B 2 61  ? -8.305  2.462   -11.726 1.00 26.73  ? 60  SER H N   1 
ATOM   2027 C CA  . SER B 2 61  ? -8.057  2.562   -10.298 1.00 31.82  ? 60  SER H CA  1 
ATOM   2028 C C   . SER B 2 61  ? -8.402  1.233   -9.627  1.00 33.57  ? 60  SER H C   1 
ATOM   2029 O O   . SER B 2 61  ? -9.397  0.597   -9.988  1.00 32.84  ? 60  SER H O   1 
ATOM   2030 C CB  . SER B 2 61  ? -8.885  3.689   -9.685  1.00 18.56  ? 60  SER H CB  1 
ATOM   2031 O OG  . SER B 2 61  ? -8.800  3.676   -8.271  1.00 29.65  ? 60  SER H OG  1 
ATOM   2032 N N   . PRO B 2 62  ? -7.597  0.784   -8.661  1.00 32.42  ? 61  PRO H N   1 
ATOM   2033 C CA  . PRO B 2 62  ? -7.908  -0.489  -7.989  1.00 26.88  ? 61  PRO H CA  1 
ATOM   2034 C C   . PRO B 2 62  ? -9.269  -0.498  -7.319  1.00 26.13  ? 61  PRO H C   1 
ATOM   2035 O O   . PRO B 2 62  ? -9.902  -1.558  -7.235  1.00 26.76  ? 61  PRO H O   1 
ATOM   2036 C CB  . PRO B 2 62  ? -6.771  -0.630  -6.967  1.00 19.63  ? 61  PRO H CB  1 
ATOM   2037 C CG  . PRO B 2 62  ? -5.654  0.189   -7.533  1.00 24.05  ? 61  PRO H CG  1 
ATOM   2038 C CD  . PRO B 2 62  ? -6.318  1.354   -8.207  1.00 26.03  ? 61  PRO H CD  1 
ATOM   2039 N N   . SER B 2 63  ? -9.742  0.654   -6.842  1.00 26.08  ? 62  SER H N   1 
ATOM   2040 C CA  . SER B 2 63  ? -11.068 0.745   -6.244  1.00 21.46  ? 62  SER H CA  1 
ATOM   2041 C C   . SER B 2 63  ? -12.189 0.586   -7.262  1.00 24.92  ? 62  SER H C   1 
ATOM   2042 O O   . SER B 2 63  ? -13.343 0.401   -6.862  1.00 32.40  ? 62  SER H O   1 
ATOM   2043 C CB  . SER B 2 63  ? -11.218 2.080   -5.515  1.00 22.85  ? 62  SER H CB  1 
ATOM   2044 O OG  . SER B 2 63  ? -10.199 2.248   -4.545  1.00 38.33  ? 62  SER H OG  1 
ATOM   2045 N N   . PHE B 2 64  ? -11.885 0.657   -8.558  1.00 24.25  ? 63  PHE H N   1 
ATOM   2046 C CA  . PHE B 2 64  ? -12.888 0.522   -9.602  1.00 27.72  ? 63  PHE H CA  1 
ATOM   2047 C C   . PHE B 2 64  ? -12.588 -0.605  -10.580 1.00 30.04  ? 63  PHE H C   1 
ATOM   2048 O O   . PHE B 2 64  ? -13.382 -0.831  -11.501 1.00 28.09  ? 63  PHE H O   1 
ATOM   2049 C CB  . PHE B 2 64  ? -13.041 1.845   -10.367 1.00 18.43  ? 63  PHE H CB  1 
ATOM   2050 C CG  . PHE B 2 64  ? -13.573 2.970   -9.525  1.00 18.98  ? 63  PHE H CG  1 
ATOM   2051 C CD1 . PHE B 2 64  ? -12.712 3.785   -8.807  1.00 21.18  ? 63  PHE H CD1 1 
ATOM   2052 C CD2 . PHE B 2 64  ? -14.934 3.210   -9.447  1.00 16.14  ? 63  PHE H CD2 1 
ATOM   2053 C CE1 . PHE B 2 64  ? -13.199 4.820   -8.029  1.00 15.05  ? 63  PHE H CE1 1 
ATOM   2054 C CE2 . PHE B 2 64  ? -15.427 4.243   -8.673  1.00 23.46  ? 63  PHE H CE2 1 
ATOM   2055 C CZ  . PHE B 2 64  ? -14.558 5.049   -7.962  1.00 21.23  ? 63  PHE H CZ  1 
ATOM   2056 N N   . GLN B 2 65  ? -11.467 -1.306  -10.416 1.00 31.58  ? 64  GLN H N   1 
ATOM   2057 C CA  . GLN B 2 65  ? -11.172 -2.466  -11.247 1.00 34.23  ? 64  GLN H CA  1 
ATOM   2058 C C   . GLN B 2 65  ? -12.273 -3.510  -11.111 1.00 31.98  ? 64  GLN H C   1 
ATOM   2059 O O   . GLN B 2 65  ? -12.650 -3.892  -10.000 1.00 26.25  ? 64  GLN H O   1 
ATOM   2060 C CB  . GLN B 2 65  ? -9.824  -3.068  -10.846 1.00 41.23  ? 64  GLN H CB  1 
ATOM   2061 C CG  . GLN B 2 65  ? -8.685  -2.791  -11.814 1.00 42.25  ? 64  GLN H CG  1 
ATOM   2062 C CD  . GLN B 2 65  ? -8.564  -3.849  -12.894 1.00 49.86  ? 64  GLN H CD  1 
ATOM   2063 O OE1 . GLN B 2 65  ? -9.263  -4.862  -12.868 1.00 65.30  ? 64  GLN H OE1 1 
ATOM   2064 N NE2 . GLN B 2 65  ? -7.669  -3.621  -13.848 1.00 51.53  ? 64  GLN H NE2 1 
ATOM   2065 N N   . GLY B 2 66  ? -12.794 -3.965  -12.250 1.00 31.19  ? 65  GLY H N   1 
ATOM   2066 C CA  . GLY B 2 66  ? -13.830 -4.975  -12.269 1.00 33.05  ? 65  GLY H CA  1 
ATOM   2067 C C   . GLY B 2 66  ? -15.232 -4.467  -12.018 1.00 35.48  ? 65  GLY H C   1 
ATOM   2068 O O   . GLY B 2 66  ? -16.190 -5.224  -12.220 1.00 44.48  ? 65  GLY H O   1 
ATOM   2069 N N   . GLN B 2 67  ? -15.390 -3.216  -11.588 1.00 32.92  ? 66  GLN H N   1 
ATOM   2070 C CA  . GLN B 2 67  ? -16.711 -2.646  -11.357 1.00 31.30  ? 66  GLN H CA  1 
ATOM   2071 C C   . GLN B 2 67  ? -17.246 -1.903  -12.571 1.00 33.90  ? 66  GLN H C   1 
ATOM   2072 O O   . GLN B 2 67  ? -18.461 -1.897  -12.801 1.00 27.65  ? 66  GLN H O   1 
ATOM   2073 C CB  . GLN B 2 67  ? -16.675 -1.694  -10.157 1.00 36.66  ? 66  GLN H CB  1 
ATOM   2074 C CG  . GLN B 2 67  ? -16.474 -2.381  -8.815  1.00 38.47  ? 66  GLN H CG  1 
ATOM   2075 C CD  . GLN B 2 67  ? -17.724 -3.087  -8.328  1.00 69.78  ? 66  GLN H CD  1 
ATOM   2076 O OE1 . GLN B 2 67  ? -18.625 -2.463  -7.765  1.00 74.01  ? 66  GLN H OE1 1 
ATOM   2077 N NE2 . GLN B 2 67  ? -17.788 -4.397  -8.543  1.00 61.38  ? 66  GLN H NE2 1 
ATOM   2078 N N   . VAL B 2 68  ? -16.365 -1.275  -13.350 1.00 30.87  ? 67  VAL H N   1 
ATOM   2079 C CA  . VAL B 2 68  ? -16.748 -0.522  -14.534 1.00 26.51  ? 67  VAL H CA  1 
ATOM   2080 C C   . VAL B 2 68  ? -15.831 -0.912  -15.683 1.00 27.89  ? 67  VAL H C   1 
ATOM   2081 O O   . VAL B 2 68  ? -14.737 -1.446  -15.488 1.00 34.61  ? 67  VAL H O   1 
ATOM   2082 C CB  . VAL B 2 68  ? -16.690 1.003   -14.304 1.00 24.09  ? 67  VAL H CB  1 
ATOM   2083 C CG1 . VAL B 2 68  ? -17.675 1.417   -13.231 1.00 30.73  ? 67  VAL H CG1 1 
ATOM   2084 C CG2 . VAL B 2 68  ? -15.281 1.427   -13.924 1.00 21.61  ? 67  VAL H CG2 1 
ATOM   2085 N N   . THR B 2 69  ? -16.297 -0.634  -16.897 1.00 23.87  ? 68  THR H N   1 
ATOM   2086 C CA  . THR B 2 69  ? -15.517 -0.832  -18.110 1.00 26.00  ? 68  THR H CA  1 
ATOM   2087 C C   . THR B 2 69  ? -15.311 0.516   -18.785 1.00 29.14  ? 68  THR H C   1 
ATOM   2088 O O   . THR B 2 69  ? -16.266 1.280   -18.955 1.00 30.36  ? 68  THR H O   1 
ATOM   2089 C CB  . THR B 2 69  ? -16.211 -1.803  -19.069 1.00 27.09  ? 68  THR H CB  1 
ATOM   2090 O OG1 . THR B 2 69  ? -16.410 -3.063  -18.418 1.00 43.71  ? 68  THR H OG1 1 
ATOM   2091 C CG2 . THR B 2 69  ? -15.368 -2.011  -20.319 1.00 24.55  ? 68  THR H CG2 1 
ATOM   2092 N N   . ILE B 2 70  ? -14.068 0.804   -19.162 1.00 25.07  ? 69  ILE H N   1 
ATOM   2093 C CA  . ILE B 2 70  ? -13.713 2.028   -19.868 1.00 18.29  ? 69  ILE H CA  1 
ATOM   2094 C C   . ILE B 2 70  ? -13.211 1.648   -21.253 1.00 29.51  ? 69  ILE H C   1 
ATOM   2095 O O   . ILE B 2 70  ? -12.309 0.812   -21.383 1.00 27.67  ? 69  ILE H O   1 
ATOM   2096 C CB  . ILE B 2 70  ? -12.652 2.840   -19.104 1.00 18.03  ? 69  ILE H CB  1 
ATOM   2097 C CG1 . ILE B 2 70  ? -13.207 3.316   -17.759 1.00 25.53  ? 69  ILE H CG1 1 
ATOM   2098 C CG2 . ILE B 2 70  ? -12.179 4.019   -19.937 1.00 27.40  ? 69  ILE H CG2 1 
ATOM   2099 C CD1 . ILE B 2 70  ? -12.251 4.195   -16.981 1.00 23.98  ? 69  ILE H CD1 1 
ATOM   2100 N N   . SER B 2 71  ? -13.797 2.256   -22.284 1.00 26.41  ? 70  SER H N   1 
ATOM   2101 C CA  . SER B 2 71  ? -13.421 1.982   -23.662 1.00 31.99  ? 70  SER H CA  1 
ATOM   2102 C C   . SER B 2 71  ? -13.469 3.278   -24.458 1.00 32.67  ? 70  SER H C   1 
ATOM   2103 O O   . SER B 2 71  ? -13.908 4.321   -23.966 1.00 32.13  ? 70  SER H O   1 
ATOM   2104 C CB  . SER B 2 71  ? -14.331 0.928   -24.301 1.00 27.93  ? 70  SER H CB  1 
ATOM   2105 O OG  . SER B 2 71  ? -15.626 1.452   -24.536 1.00 30.73  ? 70  SER H OG  1 
ATOM   2106 N N   . ALA B 2 72  ? -13.009 3.205   -25.705 1.00 33.58  ? 71  ALA H N   1 
ATOM   2107 C CA  . ALA B 2 72  ? -12.978 4.376   -26.566 1.00 36.21  ? 71  ALA H CA  1 
ATOM   2108 C C   . ALA B 2 72  ? -13.252 3.957   -28.003 1.00 37.31  ? 71  ALA H C   1 
ATOM   2109 O O   . ALA B 2 72  ? -13.050 2.802   -28.387 1.00 37.78  ? 71  ALA H O   1 
ATOM   2110 C CB  . ALA B 2 72  ? -11.636 5.109   -26.468 1.00 30.13  ? 71  ALA H CB  1 
ATOM   2111 N N   . ASP B 2 73  ? -13.724 4.918   -28.792 1.00 44.33  ? 72  ASP H N   1 
ATOM   2112 C CA  . ASP B 2 73  ? -13.936 4.751   -30.229 1.00 46.99  ? 72  ASP H CA  1 
ATOM   2113 C C   . ASP B 2 73  ? -13.126 5.845   -30.916 1.00 43.19  ? 72  ASP H C   1 
ATOM   2114 O O   . ASP B 2 73  ? -13.565 6.998   -30.986 1.00 39.47  ? 72  ASP H O   1 
ATOM   2115 C CB  . ASP B 2 73  ? -15.418 4.837   -30.587 1.00 46.67  ? 72  ASP H CB  1 
ATOM   2116 C CG  . ASP B 2 73  ? -15.704 4.414   -32.020 1.00 58.45  ? 72  ASP H CG  1 
ATOM   2117 O OD1 . ASP B 2 73  ? -16.882 4.144   -32.335 1.00 66.61  ? 72  ASP H OD1 1 
ATOM   2118 O OD2 . ASP B 2 73  ? -14.753 4.332   -32.827 1.00 64.61  ? 72  ASP H OD2 1 
ATOM   2119 N N   . LYS B 2 74  ? -11.940 5.488   -31.418 1.00 45.65  ? 73  LYS H N   1 
ATOM   2120 C CA  . LYS B 2 74  ? -11.052 6.484   -32.007 1.00 47.61  ? 73  LYS H CA  1 
ATOM   2121 C C   . LYS B 2 74  ? -11.602 7.070   -33.301 1.00 44.28  ? 73  LYS H C   1 
ATOM   2122 O O   . LYS B 2 74  ? -11.133 8.129   -33.733 1.00 46.84  ? 73  LYS H O   1 
ATOM   2123 C CB  . LYS B 2 74  ? -9.666  5.881   -32.252 1.00 45.99  ? 73  LYS H CB  1 
ATOM   2124 C CG  . LYS B 2 74  ? -9.648  4.663   -33.162 1.00 41.08  ? 73  LYS H CG  1 
ATOM   2125 C CD  . LYS B 2 74  ? -8.224  4.168   -33.377 1.00 35.63  ? 73  LYS H CD  1 
ATOM   2126 C CE  . LYS B 2 74  ? -8.181  2.984   -34.329 1.00 36.60  ? 73  LYS H CE  1 
ATOM   2127 N NZ  . LYS B 2 74  ? -8.917  1.812   -33.785 1.00 47.21  ? 73  LYS H NZ  1 
ATOM   2128 N N   . SER B 2 75  ? -12.583 6.415   -33.926 1.00 45.19  ? 74  SER H N   1 
ATOM   2129 C CA  . SER B 2 75  ? -13.160 6.942   -35.157 1.00 43.12  ? 74  SER H CA  1 
ATOM   2130 C C   . SER B 2 75  ? -14.037 8.163   -34.912 1.00 46.55  ? 74  SER H C   1 
ATOM   2131 O O   . SER B 2 75  ? -14.212 8.977   -35.825 1.00 50.19  ? 74  SER H O   1 
ATOM   2132 C CB  . SER B 2 75  ? -13.970 5.855   -35.867 1.00 40.40  ? 74  SER H CB  1 
ATOM   2133 O OG  . SER B 2 75  ? -15.069 5.436   -35.077 1.00 55.33  ? 74  SER H OG  1 
ATOM   2134 N N   . ILE B 2 76  ? -14.589 8.311   -33.707 1.00 44.34  ? 75  ILE H N   1 
ATOM   2135 C CA  . ILE B 2 76  ? -15.466 9.423   -33.373 1.00 39.15  ? 75  ILE H CA  1 
ATOM   2136 C C   . ILE B 2 76  ? -14.970 10.200  -32.160 1.00 32.79  ? 75  ILE H C   1 
ATOM   2137 O O   . ILE B 2 76  ? -15.687 11.059  -31.646 1.00 30.82  ? 75  ILE H O   1 
ATOM   2138 C CB  . ILE B 2 76  ? -16.915 8.943   -33.158 1.00 41.47  ? 75  ILE H CB  1 
ATOM   2139 C CG1 . ILE B 2 76  ? -16.978 7.933   -32.013 1.00 44.28  ? 75  ILE H CG1 1 
ATOM   2140 C CG2 . ILE B 2 76  ? -17.466 8.325   -34.434 1.00 45.90  ? 75  ILE H CG2 1 
ATOM   2141 C CD1 . ILE B 2 76  ? -18.360 7.362   -31.782 1.00 35.61  ? 75  ILE H CD1 1 
ATOM   2142 N N   . ASN B 2 77  ? -13.752 9.914   -31.691 1.00 37.93  ? 76  ASN H N   1 
ATOM   2143 C CA  . ASN B 2 77  ? -13.141 10.627  -30.566 1.00 32.19  ? 76  ASN H CA  1 
ATOM   2144 C C   . ASN B 2 77  ? -14.010 10.554  -29.312 1.00 33.23  ? 76  ASN H C   1 
ATOM   2145 O O   . ASN B 2 77  ? -14.122 11.521  -28.555 1.00 24.32  ? 76  ASN H O   1 
ATOM   2146 C CB  . ASN B 2 77  ? -12.847 12.084  -30.932 1.00 26.27  ? 76  ASN H CB  1 
ATOM   2147 C CG  . ASN B 2 77  ? -11.848 12.212  -32.062 1.00 35.22  ? 76  ASN H CG  1 
ATOM   2148 O OD1 . ASN B 2 77  ? -11.537 11.238  -32.746 1.00 50.34  ? 76  ASN H OD1 1 
ATOM   2149 N ND2 . ASN B 2 77  ? -11.340 13.422  -32.266 1.00 35.24  ? 76  ASN H ND2 1 
ATOM   2150 N N   . THR B 2 78  ? -14.625 9.396   -29.084 1.00 26.54  ? 77  THR H N   1 
ATOM   2151 C CA  . THR B 2 78  ? -15.558 9.207   -27.981 1.00 37.97  ? 77  THR H CA  1 
ATOM   2152 C C   . THR B 2 78  ? -15.026 8.149   -27.025 1.00 38.59  ? 77  THR H C   1 
ATOM   2153 O O   . THR B 2 78  ? -14.625 7.062   -27.455 1.00 35.76  ? 77  THR H O   1 
ATOM   2154 C CB  . THR B 2 78  ? -16.943 8.802   -28.494 1.00 34.86  ? 77  THR H CB  1 
ATOM   2155 O OG1 . THR B 2 78  ? -17.445 9.818   -29.372 1.00 40.60  ? 77  THR H OG1 1 
ATOM   2156 C CG2 . THR B 2 78  ? -17.910 8.620   -27.333 1.00 38.32  ? 77  THR H CG2 1 
ATOM   2157 N N   . ALA B 2 79  ? -15.028 8.470   -25.734 1.00 32.82  ? 78  ALA H N   1 
ATOM   2158 C CA  . ALA B 2 79  ? -14.676 7.534   -24.677 1.00 33.37  ? 78  ALA H CA  1 
ATOM   2159 C C   . ALA B 2 79  ? -15.925 7.174   -23.884 1.00 24.69  ? 78  ALA H C   1 
ATOM   2160 O O   . ALA B 2 79  ? -16.811 8.011   -23.689 1.00 33.50  ? 78  ALA H O   1 
ATOM   2161 C CB  . ALA B 2 79  ? -13.615 8.122   -23.745 1.00 18.63  ? 78  ALA H CB  1 
ATOM   2162 N N   . TYR B 2 80  ? -15.992 5.926   -23.429 1.00 34.67  ? 79  TYR H N   1 
ATOM   2163 C CA  . TYR B 2 80  ? -17.178 5.406   -22.768 1.00 29.04  ? 79  TYR H CA  1 
ATOM   2164 C C   . TYR B 2 80  ? -16.852 4.921   -21.361 1.00 29.76  ? 79  TYR H C   1 
ATOM   2165 O O   . TYR B 2 80  ? -15.710 4.581   -21.039 1.00 26.01  ? 79  TYR H O   1 
ATOM   2166 C CB  . TYR B 2 80  ? -17.804 4.259   -23.572 1.00 26.88  ? 79  TYR H CB  1 
ATOM   2167 C CG  . TYR B 2 80  ? -18.238 4.642   -24.968 1.00 33.87  ? 79  TYR H CG  1 
ATOM   2168 C CD1 . TYR B 2 80  ? -19.475 5.231   -25.196 1.00 36.25  ? 79  TYR H CD1 1 
ATOM   2169 C CD2 . TYR B 2 80  ? -17.415 4.404   -26.061 1.00 32.50  ? 79  TYR H CD2 1 
ATOM   2170 C CE1 . TYR B 2 80  ? -19.878 5.579   -26.472 1.00 28.51  ? 79  TYR H CE1 1 
ATOM   2171 C CE2 . TYR B 2 80  ? -17.809 4.748   -27.341 1.00 35.67  ? 79  TYR H CE2 1 
ATOM   2172 C CZ  . TYR B 2 80  ? -19.041 5.334   -27.541 1.00 41.71  ? 79  TYR H CZ  1 
ATOM   2173 O OH  . TYR B 2 80  ? -19.434 5.678   -28.814 1.00 36.79  ? 79  TYR H OH  1 
ATOM   2174 N N   . LEU B 2 81  ? -17.887 4.906   -20.525 1.00 31.37  ? 80  LEU H N   1 
ATOM   2175 C CA  . LEU B 2 81  ? -17.826 4.353   -19.177 1.00 25.77  ? 80  LEU H CA  1 
ATOM   2176 C C   . LEU B 2 81  ? -19.145 3.643   -18.921 1.00 20.63  ? 80  LEU H C   1 
ATOM   2177 O O   . LEU B 2 81  ? -20.201 4.281   -18.947 1.00 29.58  ? 80  LEU H O   1 
ATOM   2178 C CB  . LEU B 2 81  ? -17.589 5.453   -18.137 1.00 23.35  ? 80  LEU H CB  1 
ATOM   2179 C CG  . LEU B 2 81  ? -17.649 5.058   -16.661 1.00 27.69  ? 80  LEU H CG  1 
ATOM   2180 C CD1 . LEU B 2 81  ? -16.504 4.125   -16.303 1.00 30.63  ? 80  LEU H CD1 1 
ATOM   2181 C CD2 . LEU B 2 81  ? -17.633 6.296   -15.778 1.00 21.66  ? 80  LEU H CD2 1 
ATOM   2182 N N   . GLN B 2 82  ? -19.096 2.332   -18.686 1.00 21.63  ? 81  GLN H N   1 
ATOM   2183 C CA  . GLN B 2 82  ? -20.314 1.543   -18.594 1.00 29.54  ? 81  GLN H CA  1 
ATOM   2184 C C   . GLN B 2 82  ? -20.285 0.611   -17.390 1.00 29.45  ? 81  GLN H C   1 
ATOM   2185 O O   . GLN B 2 82  ? -19.223 0.176   -16.936 1.00 26.42  ? 81  GLN H O   1 
ATOM   2186 C CB  . GLN B 2 82  ? -20.557 0.721   -19.873 1.00 21.38  ? 81  GLN H CB  1 
ATOM   2187 C CG  . GLN B 2 82  ? -19.770 -0.572  -19.971 1.00 42.35  ? 81  GLN H CG  1 
ATOM   2188 C CD  . GLN B 2 82  ? -18.820 -0.578  -21.148 1.00 57.54  ? 81  GLN H CD  1 
ATOM   2189 O OE1 . GLN B 2 82  ? -17.959 0.293   -21.264 1.00 59.29  ? 81  GLN H OE1 1 
ATOM   2190 N NE2 . GLN B 2 82  ? -18.976 -1.555  -22.034 1.00 44.48  ? 81  GLN H NE2 1 
ATOM   2191 N N   . TRP B 2 83  ? -21.480 0.318   -16.881 1.00 32.80  ? 82  TRP H N   1 
ATOM   2192 C CA  . TRP B 2 83  ? -21.702 -0.657  -15.824 1.00 32.13  ? 82  TRP H CA  1 
ATOM   2193 C C   . TRP B 2 83  ? -22.510 -1.820  -16.380 1.00 33.04  ? 82  TRP H C   1 
ATOM   2194 O O   . TRP B 2 83  ? -23.437 -1.618  -17.171 1.00 31.05  ? 82  TRP H O   1 
ATOM   2195 C CB  . TRP B 2 83  ? -22.464 -0.049  -14.640 1.00 24.30  ? 82  TRP H CB  1 
ATOM   2196 C CG  . TRP B 2 83  ? -21.777 1.075   -13.927 1.00 25.04  ? 82  TRP H CG  1 
ATOM   2197 C CD1 . TRP B 2 83  ? -21.128 1.007   -12.728 1.00 26.73  ? 82  TRP H CD1 1 
ATOM   2198 C CD2 . TRP B 2 83  ? -21.696 2.441   -14.350 1.00 26.45  ? 82  TRP H CD2 1 
ATOM   2199 N NE1 . TRP B 2 83  ? -20.641 2.244   -12.383 1.00 25.31  ? 82  TRP H NE1 1 
ATOM   2200 C CE2 . TRP B 2 83  ? -20.972 3.141   -13.363 1.00 33.29  ? 82  TRP H CE2 1 
ATOM   2201 C CE3 . TRP B 2 83  ? -22.158 3.139   -15.470 1.00 23.31  ? 82  TRP H CE3 1 
ATOM   2202 C CZ2 . TRP B 2 83  ? -20.700 4.504   -13.463 1.00 27.05  ? 82  TRP H CZ2 1 
ATOM   2203 C CZ3 . TRP B 2 83  ? -21.886 4.493   -15.567 1.00 26.66  ? 82  TRP H CZ3 1 
ATOM   2204 C CH2 . TRP B 2 83  ? -21.164 5.161   -14.569 1.00 26.86  ? 82  TRP H CH2 1 
ATOM   2205 N N   . SER B 2 84  A -22.160 -3.039  -15.966 1.00 32.63  ? 82  SER H N   1 
ATOM   2206 C CA  . SER B 2 84  A -22.987 -4.189  -16.321 1.00 30.60  ? 82  SER H CA  1 
ATOM   2207 C C   . SER B 2 84  A -24.283 -4.198  -15.520 1.00 40.92  ? 82  SER H C   1 
ATOM   2208 O O   . SER B 2 84  A -25.360 -4.452  -16.071 1.00 31.34  ? 82  SER H O   1 
ATOM   2209 C CB  . SER B 2 84  A -22.211 -5.487  -16.104 1.00 38.28  ? 82  SER H CB  1 
ATOM   2210 O OG  . SER B 2 84  A -22.017 -5.744  -14.723 1.00 59.26  ? 82  SER H OG  1 
ATOM   2211 N N   . SER B 2 85  B -24.199 -3.912  -14.221 1.00 42.75  ? 82  SER H N   1 
ATOM   2212 C CA  . SER B 2 85  B -25.362 -3.897  -13.339 1.00 42.75  ? 82  SER H CA  1 
ATOM   2213 C C   . SER B 2 85  B -25.227 -2.723  -12.382 1.00 37.45  ? 82  SER H C   1 
ATOM   2214 O O   . SER B 2 85  B -24.226 -2.617  -11.667 1.00 38.98  ? 82  SER H O   1 
ATOM   2215 C CB  . SER B 2 85  B -25.487 -5.214  -12.567 1.00 38.32  ? 82  SER H CB  1 
ATOM   2216 O OG  . SER B 2 85  B -26.637 -5.220  -11.740 1.00 42.28  ? 82  SER H OG  1 
ATOM   2217 N N   . LEU B 2 86  C -26.231 -1.850  -12.363 1.00 35.11  ? 82  LEU H N   1 
ATOM   2218 C CA  . LEU B 2 86  C -26.187 -0.637  -11.559 1.00 32.28  ? 82  LEU H CA  1 
ATOM   2219 C C   . LEU B 2 86  C -26.724 -0.884  -10.156 1.00 38.38  ? 82  LEU H C   1 
ATOM   2220 O O   . LEU B 2 86  C -27.724 -1.584  -9.972  1.00 39.98  ? 82  LEU H O   1 
ATOM   2221 C CB  . LEU B 2 86  C -26.992 0.481   -12.224 1.00 33.83  ? 82  LEU H CB  1 
ATOM   2222 C CG  . LEU B 2 86  C -26.309 1.247   -13.356 1.00 28.40  ? 82  LEU H CG  1 
ATOM   2223 C CD1 . LEU B 2 86  C -27.291 2.204   -14.005 1.00 28.35  ? 82  LEU H CD1 1 
ATOM   2224 C CD2 . LEU B 2 86  C -25.096 1.998   -12.832 1.00 28.50  ? 82  LEU H CD2 1 
ATOM   2225 N N   . LYS B 2 87  ? -26.051 -0.297  -9.171  1.00 38.32  ? 83  LYS H N   1 
ATOM   2226 C CA  . LYS B 2 87  ? -26.503 -0.279  -7.790  1.00 32.79  ? 83  LYS H CA  1 
ATOM   2227 C C   . LYS B 2 87  ? -26.907 1.139   -7.410  1.00 30.61  ? 83  LYS H C   1 
ATOM   2228 O O   . LYS B 2 87  ? -26.545 2.110   -8.080  1.00 37.46  ? 83  LYS H O   1 
ATOM   2229 C CB  . LYS B 2 87  ? -25.409 -0.779  -6.839  1.00 31.16  ? 83  LYS H CB  1 
ATOM   2230 C CG  . LYS B 2 87  ? -24.688 -2.029  -7.310  1.00 35.12  ? 83  LYS H CG  1 
ATOM   2231 C CD  . LYS B 2 87  ? -23.600 -2.436  -6.328  1.00 36.50  ? 83  LYS H CD  1 
ATOM   2232 C CE  . LYS B 2 87  ? -22.653 -3.456  -6.941  1.00 40.37  ? 83  LYS H CE  1 
ATOM   2233 N NZ  . LYS B 2 87  ? -23.378 -4.645  -7.468  1.00 46.39  ? 83  LYS H NZ  1 
ATOM   2234 N N   . ALA B 2 88  ? -27.667 1.250   -6.318  1.00 31.04  ? 84  ALA H N   1 
ATOM   2235 C CA  . ALA B 2 88  ? -28.090 2.566   -5.852  1.00 24.68  ? 84  ALA H CA  1 
ATOM   2236 C C   . ALA B 2 88  ? -26.902 3.419   -5.428  1.00 30.84  ? 84  ALA H C   1 
ATOM   2237 O O   . ALA B 2 88  ? -26.959 4.651   -5.519  1.00 32.81  ? 84  ALA H O   1 
ATOM   2238 C CB  . ALA B 2 88  ? -29.083 2.425   -4.699  1.00 13.42  ? 84  ALA H CB  1 
ATOM   2239 N N   . SER B 2 89  ? -25.816 2.788   -4.975  1.00 30.70  ? 85  SER H N   1 
ATOM   2240 C CA  . SER B 2 89  ? -24.617 3.519   -4.580  1.00 25.65  ? 85  SER H CA  1 
ATOM   2241 C C   . SER B 2 89  ? -23.878 4.126   -5.766  1.00 30.90  ? 85  SER H C   1 
ATOM   2242 O O   . SER B 2 89  ? -22.946 4.909   -5.556  1.00 33.05  ? 85  SER H O   1 
ATOM   2243 C CB  . SER B 2 89  ? -23.675 2.599   -3.802  1.00 25.03  ? 85  SER H CB  1 
ATOM   2244 O OG  . SER B 2 89  ? -23.283 1.489   -4.589  1.00 35.33  ? 85  SER H OG  1 
ATOM   2245 N N   . ASP B 2 90  ? -24.261 3.781   -6.994  1.00 27.54  ? 86  ASP H N   1 
ATOM   2246 C CA  . ASP B 2 90  ? -23.674 4.379   -8.186  1.00 24.28  ? 86  ASP H CA  1 
ATOM   2247 C C   . ASP B 2 90  ? -24.227 5.766   -8.481  1.00 27.45  ? 86  ASP H C   1 
ATOM   2248 O O   . ASP B 2 90  ? -23.751 6.417   -9.418  1.00 24.45  ? 86  ASP H O   1 
ATOM   2249 C CB  . ASP B 2 90  ? -23.894 3.466   -9.396  1.00 26.09  ? 86  ASP H CB  1 
ATOM   2250 C CG  . ASP B 2 90  ? -23.060 2.201   -9.332  1.00 31.39  ? 86  ASP H CG  1 
ATOM   2251 O OD1 . ASP B 2 90  ? -21.895 2.280   -8.890  1.00 24.53  ? 86  ASP H OD1 1 
ATOM   2252 O OD2 . ASP B 2 90  ? -23.569 1.128   -9.722  1.00 31.42  ? 86  ASP H OD2 1 
ATOM   2253 N N   . THR B 2 91  ? -25.217 6.227   -7.717  1.00 22.45  ? 87  THR H N   1 
ATOM   2254 C CA  . THR B 2 91  ? -25.764 7.568   -7.881  1.00 22.90  ? 87  THR H CA  1 
ATOM   2255 C C   . THR B 2 91  ? -24.697 8.618   -7.597  1.00 25.41  ? 87  THR H C   1 
ATOM   2256 O O   . THR B 2 91  ? -24.263 8.773   -6.451  1.00 28.46  ? 87  THR H O   1 
ATOM   2257 C CB  . THR B 2 91  ? -26.967 7.775   -6.956  1.00 19.84  ? 87  THR H CB  1 
ATOM   2258 O OG1 . THR B 2 91  ? -27.993 6.830   -7.284  1.00 31.28  ? 87  THR H OG1 1 
ATOM   2259 C CG2 . THR B 2 91  ? -27.516 9.186   -7.101  1.00 18.65  ? 87  THR H CG2 1 
ATOM   2260 N N   . ALA B 2 92  ? -24.275 9.341   -8.630  1.00 14.96  ? 88  ALA H N   1 
ATOM   2261 C CA  . ALA B 2 92  ? -23.215 10.338  -8.507  1.00 25.00  ? 88  ALA H CA  1 
ATOM   2262 C C   . ALA B 2 92  ? -23.184 11.165  -9.786  1.00 20.59  ? 88  ALA H C   1 
ATOM   2263 O O   . ALA B 2 92  ? -23.965 10.941  -10.716 1.00 21.69  ? 88  ALA H O   1 
ATOM   2264 C CB  . ALA B 2 92  ? -21.857 9.682   -8.244  1.00 18.87  ? 88  ALA H CB  1 
ATOM   2265 N N   . MET B 2 93  ? -22.273 12.134  -9.818  1.00 16.41  ? 89  MET H N   1 
ATOM   2266 C CA  . MET B 2 93  ? -21.956 12.887  -11.023 1.00 15.40  ? 89  MET H CA  1 
ATOM   2267 C C   . MET B 2 93  ? -20.636 12.375  -11.581 1.00 25.60  ? 89  MET H C   1 
ATOM   2268 O O   . MET B 2 93  ? -19.645 12.276  -10.850 1.00 18.95  ? 89  MET H O   1 
ATOM   2269 C CB  . MET B 2 93  ? -21.858 14.386  -10.736 1.00 15.39  ? 89  MET H CB  1 
ATOM   2270 C CG  . MET B 2 93  ? -21.348 15.203  -11.916 1.00 30.55  ? 89  MET H CG  1 
ATOM   2271 S SD  . MET B 2 93  ? -22.652 16.079  -12.801 1.00 40.12  ? 89  MET H SD  1 
ATOM   2272 C CE  . MET B 2 93  ? -22.771 17.577  -11.825 1.00 31.02  ? 89  MET H CE  1 
ATOM   2273 N N   . TYR B 2 94  ? -20.624 12.051  -12.869 1.00 21.64  ? 90  TYR H N   1 
ATOM   2274 C CA  . TYR B 2 94  ? -19.457 11.468  -13.519 1.00 20.19  ? 90  TYR H CA  1 
ATOM   2275 C C   . TYR B 2 94  ? -18.900 12.466  -14.527 1.00 26.05  ? 90  TYR H C   1 
ATOM   2276 O O   . TYR B 2 94  ? -19.523 12.728  -15.562 1.00 22.78  ? 90  TYR H O   1 
ATOM   2277 C CB  . TYR B 2 94  ? -19.817 10.141  -14.181 1.00 18.68  ? 90  TYR H CB  1 
ATOM   2278 C CG  . TYR B 2 94  ? -20.210 9.076   -13.183 1.00 25.15  ? 90  TYR H CG  1 
ATOM   2279 C CD1 . TYR B 2 94  ? -21.524 8.949   -12.755 1.00 24.47  ? 90  TYR H CD1 1 
ATOM   2280 C CD2 . TYR B 2 94  ? -19.262 8.209   -12.656 1.00 21.51  ? 90  TYR H CD2 1 
ATOM   2281 C CE1 . TYR B 2 94  ? -21.885 7.981   -11.837 1.00 28.72  ? 90  TYR H CE1 1 
ATOM   2282 C CE2 . TYR B 2 94  ? -19.614 7.239   -11.738 1.00 22.97  ? 90  TYR H CE2 1 
ATOM   2283 C CZ  . TYR B 2 94  ? -20.926 7.130   -11.332 1.00 25.58  ? 90  TYR H CZ  1 
ATOM   2284 O OH  . TYR B 2 94  ? -21.280 6.165   -10.417 1.00 28.37  ? 90  TYR H OH  1 
ATOM   2285 N N   . TYR B 2 95  ? -17.733 13.020  -14.217 1.00 20.89  ? 91  TYR H N   1 
ATOM   2286 C CA  . TYR B 2 95  ? -17.015 13.892  -15.132 1.00 21.38  ? 91  TYR H CA  1 
ATOM   2287 C C   . TYR B 2 95  ? -16.041 13.078  -15.972 1.00 22.12  ? 91  TYR H C   1 
ATOM   2288 O O   . TYR B 2 95  ? -15.504 12.062  -15.523 1.00 33.03  ? 91  TYR H O   1 
ATOM   2289 C CB  . TYR B 2 95  ? -16.234 14.968  -14.372 1.00 21.51  ? 91  TYR H CB  1 
ATOM   2290 C CG  . TYR B 2 95  ? -17.062 15.899  -13.517 1.00 18.09  ? 91  TYR H CG  1 
ATOM   2291 C CD1 . TYR B 2 95  ? -17.709 16.994  -14.074 1.00 15.85  ? 91  TYR H CD1 1 
ATOM   2292 C CD2 . TYR B 2 95  ? -17.169 15.703  -12.146 1.00 15.18  ? 91  TYR H CD2 1 
ATOM   2293 C CE1 . TYR B 2 95  ? -18.456 17.855  -13.294 1.00 24.07  ? 91  TYR H CE1 1 
ATOM   2294 C CE2 . TYR B 2 95  ? -17.913 16.560  -11.357 1.00 19.51  ? 91  TYR H CE2 1 
ATOM   2295 C CZ  . TYR B 2 95  ? -18.555 17.634  -11.937 1.00 23.13  ? 91  TYR H CZ  1 
ATOM   2296 O OH  . TYR B 2 95  ? -19.299 18.493  -11.162 1.00 22.60  ? 91  TYR H OH  1 
ATOM   2297 N N   . CYS B 2 96  ? -15.812 13.535  -17.198 1.00 19.78  ? 92  CYS H N   1 
ATOM   2298 C CA  . CYS B 2 96  ? -14.678 13.080  -17.989 1.00 28.51  ? 92  CYS H CA  1 
ATOM   2299 C C   . CYS B 2 96  ? -13.675 14.219  -18.083 1.00 22.93  ? 92  CYS H C   1 
ATOM   2300 O O   . CYS B 2 96  ? -14.051 15.365  -18.352 1.00 28.78  ? 92  CYS H O   1 
ATOM   2301 C CB  . CYS B 2 96  ? -15.096 12.603  -19.384 1.00 21.66  ? 92  CYS H CB  1 
ATOM   2302 S SG  . CYS B 2 96  ? -15.804 13.829  -20.508 1.00 43.02  ? 92  CYS H SG  1 
ATOM   2303 N N   . ALA B 2 97  ? -12.409 13.906  -17.831 1.00 18.58  ? 93  ALA H N   1 
ATOM   2304 C CA  . ALA B 2 97  ? -11.336 14.886  -17.844 1.00 24.05  ? 93  ALA H CA  1 
ATOM   2305 C C   . ALA B 2 97  ? -10.268 14.448  -18.833 1.00 29.55  ? 93  ALA H C   1 
ATOM   2306 O O   . ALA B 2 97  ? -9.924  13.264  -18.907 1.00 24.65  ? 93  ALA H O   1 
ATOM   2307 C CB  . ALA B 2 97  ? -10.724 15.061  -16.451 1.00 23.75  ? 93  ALA H CB  1 
ATOM   2308 N N   . GLY B 2 98  ? -9.752  15.407  -19.591 1.00 33.48  ? 94  GLY H N   1 
ATOM   2309 C CA  . GLY B 2 98  ? -8.718  15.155  -20.583 1.00 20.20  ? 94  GLY H CA  1 
ATOM   2310 C C   . GLY B 2 98  ? -7.377  15.679  -20.101 1.00 17.41  ? 94  GLY H C   1 
ATOM   2311 O O   . GLY B 2 98  ? -7.305  16.732  -19.460 1.00 27.72  ? 94  GLY H O   1 
ATOM   2312 N N   . SER B 2 99  ? -6.321  14.931  -20.406 1.00 18.46  ? 95  SER H N   1 
ATOM   2313 C CA  . SER B 2 99  ? -4.958  15.322  -20.085 1.00 22.68  ? 95  SER H CA  1 
ATOM   2314 C C   . SER B 2 99  ? -4.081  15.107  -21.308 1.00 29.52  ? 95  SER H C   1 
ATOM   2315 O O   . SER B 2 99  ? -4.192  14.082  -21.987 1.00 29.50  ? 95  SER H O   1 
ATOM   2316 C CB  . SER B 2 99  ? -4.409  14.525  -18.893 1.00 22.47  ? 95  SER H CB  1 
ATOM   2317 O OG  . SER B 2 99  ? -4.449  13.131  -19.145 1.00 25.24  ? 95  SER H OG  1 
ATOM   2318 N N   . SER B 2 100 ? -3.215  16.078  -21.587 1.00 23.15  ? 96  SER H N   1 
ATOM   2319 C CA  . SER B 2 100 ? -2.283  15.982  -22.709 1.00 27.82  ? 96  SER H CA  1 
ATOM   2320 C C   . SER B 2 100 ? -1.135  15.080  -22.274 1.00 25.67  ? 96  SER H C   1 
ATOM   2321 O O   . SER B 2 100 ? -0.134  15.530  -21.715 1.00 32.70  ? 96  SER H O   1 
ATOM   2322 C CB  . SER B 2 100 ? -1.796  17.364  -23.129 1.00 30.31  ? 96  SER H CB  1 
ATOM   2323 O OG  . SER B 2 100 ? -1.211  17.331  -24.419 1.00 26.47  ? 96  SER H OG  1 
ATOM   2324 N N   . GLY B 2 101 ? -1.287  13.786  -22.530 1.00 27.15  ? 97  GLY H N   1 
ATOM   2325 C CA  . GLY B 2 101 ? -0.344  12.794  -22.061 1.00 36.49  ? 97  GLY H CA  1 
ATOM   2326 C C   . GLY B 2 101 ? -0.700  12.267  -20.681 1.00 38.90  ? 97  GLY H C   1 
ATOM   2327 O O   . GLY B 2 101 ? -1.450  12.876  -19.919 1.00 33.84  ? 97  GLY H O   1 
ATOM   2328 N N   . ILE B 2 102 ? -0.147  11.102  -20.361 1.00 33.65  ? 98  ILE H N   1 
ATOM   2329 C CA  . ILE B 2 102 ? -0.384  10.487  -19.064 1.00 26.09  ? 98  ILE H CA  1 
ATOM   2330 C C   . ILE B 2 102 ? 0.671   10.987  -18.083 1.00 28.83  ? 98  ILE H C   1 
ATOM   2331 O O   . ILE B 2 102 ? 1.734   11.477  -18.471 1.00 30.36  ? 98  ILE H O   1 
ATOM   2332 C CB  . ILE B 2 102 ? -0.398  8.946   -19.154 1.00 30.30  ? 98  ILE H CB  1 
ATOM   2333 C CG1 . ILE B 2 102 ? -1.223  8.353   -18.007 1.00 30.65  ? 98  ILE H CG1 1 
ATOM   2334 C CG2 . ILE B 2 102 ? 1.016   8.391   -19.143 1.00 29.82  ? 98  ILE H CG2 1 
ATOM   2335 C CD1 . ILE B 2 102 ? -1.656  6.925   -18.236 1.00 19.55  ? 98  ILE H CD1 1 
ATOM   2336 N N   . SER B 2 103 ? 0.364   10.864  -16.789 1.00 26.66  ? 99  SER H N   1 
ATOM   2337 C CA  . SER B 2 103 ? 1.149   11.491  -15.723 1.00 24.85  ? 99  SER H CA  1 
ATOM   2338 C C   . SER B 2 103 ? 1.271   12.995  -15.953 1.00 23.35  ? 99  SER H C   1 
ATOM   2339 O O   . SER B 2 103 ? 2.336   13.591  -15.775 1.00 22.25  ? 99  SER H O   1 
ATOM   2340 C CB  . SER B 2 103 ? 2.526   10.839  -15.578 1.00 25.30  ? 99  SER H CB  1 
ATOM   2341 O OG  . SER B 2 103 ? 2.425   9.595   -14.908 1.00 25.66  ? 99  SER H OG  1 
ATOM   2342 N N   . THR B 2 104 ? 0.168   13.605  -16.364 1.00 28.72  ? 100 THR H N   1 
ATOM   2343 C CA  . THR B 2 104 ? 0.018   15.037  -16.563 1.00 23.34  ? 100 THR H CA  1 
ATOM   2344 C C   . THR B 2 104 ? -1.300  15.465  -15.940 1.00 26.26  ? 100 THR H C   1 
ATOM   2345 O O   . THR B 2 104 ? -2.203  14.642  -15.759 1.00 32.25  ? 100 THR H O   1 
ATOM   2346 C CB  . THR B 2 104 ? 0.037   15.404  -18.056 1.00 31.78  ? 100 THR H CB  1 
ATOM   2347 O OG1 . THR B 2 104 ? -1.022  14.720  -18.736 1.00 27.88  ? 100 THR H OG1 1 
ATOM   2348 C CG2 . THR B 2 104 ? 1.372   15.030  -18.686 1.00 22.41  ? 100 THR H CG2 1 
ATOM   2349 N N   . PRO B 2 105 A -1.440  16.740  -15.583 1.00 29.46  ? 100 PRO H N   1 
ATOM   2350 C CA  . PRO B 2 105 A -2.703  17.200  -14.997 1.00 28.05  ? 100 PRO H CA  1 
ATOM   2351 C C   . PRO B 2 105 A -3.835  17.182  -16.013 1.00 22.29  ? 100 PRO H C   1 
ATOM   2352 O O   . PRO B 2 105 A -3.627  17.239  -17.227 1.00 31.90  ? 100 PRO H O   1 
ATOM   2353 C CB  . PRO B 2 105 A -2.387  18.630  -14.546 1.00 30.74  ? 100 PRO H CB  1 
ATOM   2354 C CG  . PRO B 2 105 A -1.280  19.058  -15.442 1.00 29.37  ? 100 PRO H CG  1 
ATOM   2355 C CD  . PRO B 2 105 A -0.449  17.828  -15.659 1.00 28.80  ? 100 PRO H CD  1 
ATOM   2356 N N   . MET B 2 106 B -5.056  17.094  -15.488 1.00 26.22  ? 100 MET H N   1 
ATOM   2357 C CA  . MET B 2 106 B -6.271  17.124  -16.301 1.00 29.00  ? 100 MET H CA  1 
ATOM   2358 C C   . MET B 2 106 B -6.663  18.582  -16.508 1.00 29.23  ? 100 MET H C   1 
ATOM   2359 O O   . MET B 2 106 B -7.223  19.219  -15.612 1.00 25.95  ? 100 MET H O   1 
ATOM   2360 C CB  . MET B 2 106 B -7.388  16.338  -15.623 1.00 24.03  ? 100 MET H CB  1 
ATOM   2361 C CG  . MET B 2 106 B -7.135  14.843  -15.510 1.00 22.87  ? 100 MET H CG  1 
ATOM   2362 S SD  . MET B 2 106 B -7.999  14.123  -14.098 1.00 26.73  ? 100 MET H SD  1 
ATOM   2363 C CE  . MET B 2 106 B -8.507  12.541  -14.766 1.00 32.00  ? 100 MET H CE  1 
ATOM   2364 N N   . ASP B 2 107 ? -6.378  19.114  -17.698 1.00 28.37  ? 101 ASP H N   1 
ATOM   2365 C CA  . ASP B 2 107 ? -6.570  20.536  -17.953 1.00 21.95  ? 101 ASP H CA  1 
ATOM   2366 C C   . ASP B 2 107 ? -7.925  20.872  -18.563 1.00 29.28  ? 101 ASP H C   1 
ATOM   2367 O O   . ASP B 2 107 ? -8.373  22.018  -18.437 1.00 37.23  ? 101 ASP H O   1 
ATOM   2368 C CB  . ASP B 2 107 ? -5.449  21.069  -18.856 1.00 24.32  ? 101 ASP H CB  1 
ATOM   2369 C CG  . ASP B 2 107 ? -5.235  20.220  -20.096 1.00 41.37  ? 101 ASP H CG  1 
ATOM   2370 O OD1 . ASP B 2 107 ? -6.187  19.547  -20.542 1.00 37.87  ? 101 ASP H OD1 1 
ATOM   2371 O OD2 . ASP B 2 107 ? -4.102  20.221  -20.622 1.00 46.19  ? 101 ASP H OD2 1 
ATOM   2372 N N   . VAL B 2 108 ? -8.588  19.919  -19.215 1.00 26.67  ? 102 VAL H N   1 
ATOM   2373 C CA  . VAL B 2 108 ? -9.918  20.133  -19.775 1.00 28.73  ? 102 VAL H CA  1 
ATOM   2374 C C   . VAL B 2 108 ? -10.893 19.190  -19.083 1.00 29.74  ? 102 VAL H C   1 
ATOM   2375 O O   . VAL B 2 108 ? -10.568 18.029  -18.811 1.00 24.54  ? 102 VAL H O   1 
ATOM   2376 C CB  . VAL B 2 108 ? -9.948  19.942  -21.308 1.00 27.40  ? 102 VAL H CB  1 
ATOM   2377 C CG1 . VAL B 2 108 ? -8.964  20.889  -21.981 1.00 29.46  ? 102 VAL H CG1 1 
ATOM   2378 C CG2 . VAL B 2 108 ? -9.655  18.503  -21.690 1.00 27.91  ? 102 VAL H CG2 1 
ATOM   2379 N N   . TRP B 2 109 ? -12.081 19.705  -18.775 1.00 30.69  ? 103 TRP H N   1 
ATOM   2380 C CA  . TRP B 2 109 ? -13.102 18.956  -18.060 1.00 19.85  ? 103 TRP H CA  1 
ATOM   2381 C C   . TRP B 2 109 ? -14.435 19.082  -18.779 1.00 25.06  ? 103 TRP H C   1 
ATOM   2382 O O   . TRP B 2 109 ? -14.775 20.150  -19.295 1.00 30.80  ? 103 TRP H O   1 
ATOM   2383 C CB  . TRP B 2 109 ? -13.253 19.454  -16.619 1.00 16.43  ? 103 TRP H CB  1 
ATOM   2384 C CG  . TRP B 2 109 ? -12.114 19.090  -15.723 1.00 23.88  ? 103 TRP H CG  1 
ATOM   2385 C CD1 . TRP B 2 109 ? -10.888 19.686  -15.669 1.00 23.31  ? 103 TRP H CD1 1 
ATOM   2386 C CD2 . TRP B 2 109 ? -12.099 18.052  -14.736 1.00 27.67  ? 103 TRP H CD2 1 
ATOM   2387 N NE1 . TRP B 2 109 ? -10.108 19.079  -14.714 1.00 22.68  ? 103 TRP H NE1 1 
ATOM   2388 C CE2 . TRP B 2 109 ? -10.829 18.073  -14.127 1.00 28.34  ? 103 TRP H CE2 1 
ATOM   2389 C CE3 . TRP B 2 109 ? -13.036 17.105  -14.311 1.00 22.27  ? 103 TRP H CE3 1 
ATOM   2390 C CZ2 . TRP B 2 109 ? -10.471 17.183  -13.115 1.00 21.98  ? 103 TRP H CZ2 1 
ATOM   2391 C CZ3 . TRP B 2 109 ? -12.680 16.223  -13.307 1.00 19.00  ? 103 TRP H CZ3 1 
ATOM   2392 C CH2 . TRP B 2 109 ? -11.409 16.269  -12.720 1.00 28.47  ? 103 TRP H CH2 1 
ATOM   2393 N N   . GLY B 2 110 ? -15.188 17.985  -18.807 1.00 21.06  ? 104 GLY H N   1 
ATOM   2394 C CA  . GLY B 2 110 ? -16.540 18.030  -19.316 1.00 25.43  ? 104 GLY H CA  1 
ATOM   2395 C C   . GLY B 2 110 ? -17.502 18.636  -18.313 1.00 26.43  ? 104 GLY H C   1 
ATOM   2396 O O   . GLY B 2 110 ? -17.169 18.886  -17.155 1.00 16.40  ? 104 GLY H O   1 
ATOM   2397 N N   . ARG B 2 111 ? -18.728 18.880  -18.781 1.00 34.81  ? 105 ARG H N   1 
ATOM   2398 C CA  . ARG B 2 111 ? -19.751 19.444  -17.908 1.00 31.53  ? 105 ARG H CA  1 
ATOM   2399 C C   . ARG B 2 111 ? -20.216 18.456  -16.848 1.00 27.43  ? 105 ARG H C   1 
ATOM   2400 O O   . ARG B 2 111 ? -20.735 18.879  -15.809 1.00 29.68  ? 105 ARG H O   1 
ATOM   2401 C CB  . ARG B 2 111 ? -20.946 19.922  -18.736 1.00 28.23  ? 105 ARG H CB  1 
ATOM   2402 C CG  . ARG B 2 111 ? -20.617 21.033  -19.719 1.00 36.52  ? 105 ARG H CG  1 
ATOM   2403 C CD  . ARG B 2 111 ? -20.020 22.237  -19.008 1.00 47.84  ? 105 ARG H CD  1 
ATOM   2404 N NE  . ARG B 2 111 ? -20.896 22.742  -17.958 1.00 53.37  ? 105 ARG H NE  1 
ATOM   2405 C CZ  . ARG B 2 111 ? -20.612 23.776  -17.177 1.00 58.54  ? 105 ARG H CZ  1 
ATOM   2406 N NH1 . ARG B 2 111 ? -19.477 24.445  -17.302 1.00 51.73  ? 105 ARG H NH1 1 
ATOM   2407 N NH2 . ARG B 2 111 ? -21.489 24.149  -16.248 1.00 58.15  ? 105 ARG H NH2 1 
ATOM   2408 N N   . GLY B 2 112 ? -20.042 17.166  -17.081 1.00 22.83  ? 106 GLY H N   1 
ATOM   2409 C CA  . GLY B 2 112 ? -20.475 16.154  -16.141 1.00 24.75  ? 106 GLY H CA  1 
ATOM   2410 C C   . GLY B 2 112 ? -21.795 15.527  -16.545 1.00 30.08  ? 106 GLY H C   1 
ATOM   2411 O O   . GLY B 2 112 ? -22.638 16.146  -17.205 1.00 33.34  ? 106 GLY H O   1 
ATOM   2412 N N   . THR B 2 113 ? -21.981 14.271  -16.148 1.00 26.05  ? 107 THR H N   1 
ATOM   2413 C CA  . THR B 2 113 ? -23.210 13.533  -16.406 1.00 22.18  ? 107 THR H CA  1 
ATOM   2414 C C   . THR B 2 113 ? -23.773 13.048  -15.079 1.00 22.26  ? 107 THR H C   1 
ATOM   2415 O O   . THR B 2 113 ? -23.096 12.323  -14.342 1.00 27.07  ? 107 THR H O   1 
ATOM   2416 C CB  . THR B 2 113 ? -22.958 12.353  -17.349 1.00 25.20  ? 107 THR H CB  1 
ATOM   2417 O OG1 . THR B 2 113 ? -22.553 12.843  -18.633 1.00 37.86  ? 107 THR H OG1 1 
ATOM   2418 C CG2 . THR B 2 113 ? -24.218 11.516  -17.506 1.00 20.39  ? 107 THR H CG2 1 
ATOM   2419 N N   . THR B 2 114 ? -25.004 13.450  -14.776 1.00 23.40  ? 108 THR H N   1 
ATOM   2420 C CA  . THR B 2 114 ? -25.665 13.012  -13.555 1.00 24.72  ? 108 THR H CA  1 
ATOM   2421 C C   . THR B 2 114 ? -26.301 11.646  -13.774 1.00 23.11  ? 108 THR H C   1 
ATOM   2422 O O   . THR B 2 114 ? -27.045 11.445  -14.739 1.00 24.64  ? 108 THR H O   1 
ATOM   2423 C CB  . THR B 2 114 ? -26.723 14.028  -13.122 1.00 21.49  ? 108 THR H CB  1 
ATOM   2424 O OG1 . THR B 2 114 ? -26.079 15.215  -12.644 1.00 31.21  ? 108 THR H OG1 1 
ATOM   2425 C CG2 . THR B 2 114 ? -27.601 13.453  -12.019 1.00 32.05  ? 108 THR H CG2 1 
ATOM   2426 N N   . VAL B 2 115 ? -25.999 10.707  -12.882 1.00 18.81  ? 109 VAL H N   1 
ATOM   2427 C CA  . VAL B 2 115 ? -26.559 9.362   -12.925 1.00 19.43  ? 109 VAL H CA  1 
ATOM   2428 C C   . VAL B 2 115 ? -27.295 9.122   -11.616 1.00 24.39  ? 109 VAL H C   1 
ATOM   2429 O O   . VAL B 2 115 ? -26.697 9.206   -10.536 1.00 21.35  ? 109 VAL H O   1 
ATOM   2430 C CB  . VAL B 2 115 ? -25.477 8.295   -13.147 1.00 30.99  ? 109 VAL H CB  1 
ATOM   2431 C CG1 . VAL B 2 115 ? -26.091 6.904   -13.091 1.00 23.50  ? 109 VAL H CG1 1 
ATOM   2432 C CG2 . VAL B 2 115 ? -24.772 8.521   -14.476 1.00 25.45  ? 109 VAL H CG2 1 
ATOM   2433 N N   . THR B 2 116 ? -28.588 8.823   -11.711 1.00 26.11  ? 110 THR H N   1 
ATOM   2434 C CA  . THR B 2 116 ? -29.413 8.508   -10.552 1.00 27.70  ? 110 THR H CA  1 
ATOM   2435 C C   . THR B 2 116 ? -29.905 7.075   -10.686 1.00 25.87  ? 110 THR H C   1 
ATOM   2436 O O   . THR B 2 116 ? -30.571 6.733   -11.669 1.00 30.44  ? 110 THR H O   1 
ATOM   2437 C CB  . THR B 2 116 ? -30.597 9.472   -10.435 1.00 25.33  ? 110 THR H CB  1 
ATOM   2438 O OG1 . THR B 2 116 ? -30.116 10.820  -10.371 1.00 26.74  ? 110 THR H OG1 1 
ATOM   2439 C CG2 . THR B 2 116 ? -31.406 9.170   -9.181  1.00 23.64  ? 110 THR H CG2 1 
ATOM   2440 N N   . VAL B 2 117 ? -29.576 6.242   -9.703  1.00 20.21  ? 111 VAL H N   1 
ATOM   2441 C CA  . VAL B 2 117 ? -30.026 4.856   -9.659  1.00 31.52  ? 111 VAL H CA  1 
ATOM   2442 C C   . VAL B 2 117 ? -30.909 4.698   -8.432  1.00 29.34  ? 111 VAL H C   1 
ATOM   2443 O O   . VAL B 2 117 ? -30.441 4.857   -7.298  1.00 22.94  ? 111 VAL H O   1 
ATOM   2444 C CB  . VAL B 2 117 ? -28.851 3.868   -9.622  1.00 27.45  ? 111 VAL H CB  1 
ATOM   2445 C CG1 . VAL B 2 117 ? -29.369 2.439   -9.597  1.00 28.42  ? 111 VAL H CG1 1 
ATOM   2446 C CG2 . VAL B 2 117 ? -27.937 4.088   -10.817 1.00 29.18  ? 111 VAL H CG2 1 
ATOM   2447 N N   . SER B 2 118 ? -32.181 4.386   -8.659  1.00 32.39  ? 112 SER H N   1 
ATOM   2448 C CA  . SER B 2 118 ? -33.144 4.280   -7.575  1.00 35.02  ? 112 SER H CA  1 
ATOM   2449 C C   . SER B 2 118 ? -34.278 3.367   -8.011  1.00 39.86  ? 112 SER H C   1 
ATOM   2450 O O   . SER B 2 118 ? -34.564 3.236   -9.204  1.00 35.85  ? 112 SER H O   1 
ATOM   2451 C CB  . SER B 2 118 ? -33.687 5.657   -7.176  1.00 26.23  ? 112 SER H CB  1 
ATOM   2452 O OG  . SER B 2 118 ? -34.664 5.548   -6.157  1.00 32.22  ? 112 SER H OG  1 
ATOM   2453 N N   . SER B 2 119 ? -34.918 2.735   -7.028  1.00 45.91  ? 113 SER H N   1 
ATOM   2454 C CA  . SER B 2 119 ? -36.092 1.915   -7.292  1.00 35.74  ? 113 SER H CA  1 
ATOM   2455 C C   . SER B 2 119 ? -37.354 2.745   -7.481  1.00 41.22  ? 113 SER H C   1 
ATOM   2456 O O   . SER B 2 119 ? -38.377 2.199   -7.909  1.00 46.85  ? 113 SER H O   1 
ATOM   2457 C CB  . SER B 2 119 ? -36.299 0.912   -6.155  1.00 35.34  ? 113 SER H CB  1 
ATOM   2458 O OG  . SER B 2 119 ? -36.455 1.576   -4.913  1.00 47.37  ? 113 SER H OG  1 
ATOM   2459 N N   . ALA B 2 120 ? -37.304 4.039   -7.178  1.00 36.27  ? 114 ALA H N   1 
ATOM   2460 C CA  . ALA B 2 120 ? -38.475 4.893   -7.298  1.00 34.95  ? 114 ALA H CA  1 
ATOM   2461 C C   . ALA B 2 120 ? -38.823 5.141   -8.761  1.00 36.58  ? 114 ALA H C   1 
ATOM   2462 O O   . ALA B 2 120 ? -37.955 5.162   -9.638  1.00 39.90  ? 114 ALA H O   1 
ATOM   2463 C CB  . ALA B 2 120 ? -38.240 6.225   -6.586  1.00 32.15  ? 114 ALA H CB  1 
ATOM   2464 N N   . SER B 2 121 ? -40.112 5.333   -9.014  1.00 41.32  ? 115 SER H N   1 
ATOM   2465 C CA  . SER B 2 121 ? -40.619 5.650   -10.339 1.00 37.01  ? 115 SER H CA  1 
ATOM   2466 C C   . SER B 2 121 ? -40.902 7.145   -10.448 1.00 37.11  ? 115 SER H C   1 
ATOM   2467 O O   . SER B 2 121 ? -40.918 7.875   -9.454  1.00 39.71  ? 115 SER H O   1 
ATOM   2468 C CB  . SER B 2 121 ? -41.884 4.839   -10.638 1.00 40.50  ? 115 SER H CB  1 
ATOM   2469 O OG  . SER B 2 121 ? -41.641 3.450   -10.501 1.00 43.91  ? 115 SER H OG  1 
ATOM   2470 N N   . THR B 2 122 ? -41.121 7.596   -11.680 1.00 32.31  ? 116 THR H N   1 
ATOM   2471 C CA  . THR B 2 122 ? -41.404 9.005   -11.918 1.00 32.63  ? 116 THR H CA  1 
ATOM   2472 C C   . THR B 2 122 ? -42.704 9.408   -11.233 1.00 39.97  ? 116 THR H C   1 
ATOM   2473 O O   . THR B 2 122 ? -43.735 8.749   -11.393 1.00 45.87  ? 116 THR H O   1 
ATOM   2474 C CB  . THR B 2 122 ? -41.488 9.282   -13.419 1.00 28.34  ? 116 THR H CB  1 
ATOM   2475 O OG1 . THR B 2 122 ? -40.261 8.892   -14.048 1.00 25.74  ? 116 THR H OG1 1 
ATOM   2476 C CG2 . THR B 2 122 ? -41.732 10.759  -13.674 1.00 35.69  ? 116 THR H CG2 1 
ATOM   2477 N N   . LYS B 2 123 ? -42.652 10.496  -10.466 1.00 37.34  ? 117 LYS H N   1 
ATOM   2478 C CA  . LYS B 2 123 ? -43.811 10.989  -9.738  1.00 30.71  ? 117 LYS H CA  1 
ATOM   2479 C C   . LYS B 2 123 ? -43.805 12.510  -9.743  1.00 42.84  ? 117 LYS H C   1 
ATOM   2480 O O   . LYS B 2 123 ? -42.759 13.135  -9.544  1.00 36.27  ? 117 LYS H O   1 
ATOM   2481 C CB  . LYS B 2 123 ? -43.828 10.468  -8.294  1.00 30.70  ? 117 LYS H CB  1 
ATOM   2482 C CG  . LYS B 2 123 ? -45.073 10.848  -7.510  1.00 38.66  ? 117 LYS H CG  1 
ATOM   2483 C CD  . LYS B 2 123 ? -45.017 10.311  -6.090  1.00 42.18  ? 117 LYS H CD  1 
ATOM   2484 C CE  . LYS B 2 123 ? -46.266 10.684  -5.308  1.00 53.05  ? 117 LYS H CE  1 
ATOM   2485 N NZ  . LYS B 2 123 ? -46.448 12.160  -5.227  1.00 49.65  ? 117 LYS H NZ  1 
ATOM   2486 N N   . GLY B 2 124 ? -44.979 13.098  -9.968  1.00 45.67  ? 118 GLY H N   1 
ATOM   2487 C CA  . GLY B 2 124 ? -45.124 14.534  -9.998  1.00 32.58  ? 118 GLY H CA  1 
ATOM   2488 C C   . GLY B 2 124 ? -45.217 15.138  -8.612  1.00 37.33  ? 118 GLY H C   1 
ATOM   2489 O O   . GLY B 2 124 ? -45.753 14.533  -7.678  1.00 45.46  ? 118 GLY H O   1 
ATOM   2490 N N   . PRO B 2 125 ? -44.693 16.350  -8.453  1.00 32.56  ? 119 PRO H N   1 
ATOM   2491 C CA  . PRO B 2 125 ? -44.694 16.989  -7.135  1.00 35.52  ? 119 PRO H CA  1 
ATOM   2492 C C   . PRO B 2 125 ? -46.078 17.472  -6.729  1.00 35.63  ? 119 PRO H C   1 
ATOM   2493 O O   . PRO B 2 125 ? -46.950 17.742  -7.557  1.00 45.65  ? 119 PRO H O   1 
ATOM   2494 C CB  . PRO B 2 125 ? -43.734 18.168  -7.315  1.00 30.35  ? 119 PRO H CB  1 
ATOM   2495 C CG  . PRO B 2 125 ? -43.836 18.500  -8.763  1.00 29.78  ? 119 PRO H CG  1 
ATOM   2496 C CD  . PRO B 2 125 ? -44.038 17.187  -9.473  1.00 36.87  ? 119 PRO H CD  1 
ATOM   2497 N N   . SER B 2 126 ? -46.265 17.576  -5.416  1.00 37.51  ? 120 SER H N   1 
ATOM   2498 C CA  . SER B 2 126 ? -47.426 18.226  -4.823  1.00 35.14  ? 120 SER H CA  1 
ATOM   2499 C C   . SER B 2 126 ? -46.962 19.548  -4.229  1.00 37.44  ? 120 SER H C   1 
ATOM   2500 O O   . SER B 2 126 ? -46.071 19.567  -3.374  1.00 40.03  ? 120 SER H O   1 
ATOM   2501 C CB  . SER B 2 126 ? -48.069 17.345  -3.752  1.00 35.19  ? 120 SER H CB  1 
ATOM   2502 O OG  . SER B 2 126 ? -48.471 16.097  -4.289  1.00 39.48  ? 120 SER H OG  1 
ATOM   2503 N N   . VAL B 2 127 ? -47.561 20.645  -4.680  1.00 40.86  ? 121 VAL H N   1 
ATOM   2504 C CA  . VAL B 2 127 ? -47.135 21.986  -4.298  1.00 31.02  ? 121 VAL H CA  1 
ATOM   2505 C C   . VAL B 2 127 ? -48.104 22.519  -3.253  1.00 32.46  ? 121 VAL H C   1 
ATOM   2506 O O   . VAL B 2 127 ? -49.315 22.585  -3.493  1.00 41.74  ? 121 VAL H O   1 
ATOM   2507 C CB  . VAL B 2 127 ? -47.064 22.919  -5.516  1.00 28.81  ? 121 VAL H CB  1 
ATOM   2508 C CG1 . VAL B 2 127 ? -46.412 24.237  -5.134  1.00 26.90  ? 121 VAL H CG1 1 
ATOM   2509 C CG2 . VAL B 2 127 ? -46.309 22.249  -6.654  1.00 30.48  ? 121 VAL H CG2 1 
ATOM   2510 N N   . PHE B 2 128 ? -47.571 22.905  -2.093  1.00 28.06  ? 122 PHE H N   1 
ATOM   2511 C CA  . PHE B 2 128 ? -48.386 23.433  -1.016  1.00 37.89  ? 122 PHE H CA  1 
ATOM   2512 C C   . PHE B 2 128 ? -47.910 24.826  -0.622  1.00 36.80  ? 122 PHE H C   1 
ATOM   2513 O O   . PHE B 2 128 ? -46.701 25.072  -0.555  1.00 39.18  ? 122 PHE H O   1 
ATOM   2514 C CB  . PHE B 2 128 ? -48.345 22.516  0.216   1.00 35.79  ? 122 PHE H CB  1 
ATOM   2515 C CG  . PHE B 2 128 ? -48.748 21.099  -0.070  1.00 40.55  ? 122 PHE H CG  1 
ATOM   2516 C CD1 . PHE B 2 128 ? -47.882 20.052  0.194   1.00 42.68  ? 122 PHE H CD1 1 
ATOM   2517 C CD2 . PHE B 2 128 ? -49.991 20.815  -0.609  1.00 37.18  ? 122 PHE H CD2 1 
ATOM   2518 C CE1 . PHE B 2 128 ? -48.251 18.745  -0.069  1.00 49.05  ? 122 PHE H CE1 1 
ATOM   2519 C CE2 . PHE B 2 128 ? -50.365 19.512  -0.875  1.00 38.81  ? 122 PHE H CE2 1 
ATOM   2520 C CZ  . PHE B 2 128 ? -49.494 18.476  -0.604  1.00 35.04  ? 122 PHE H CZ  1 
ATOM   2521 N N   . PRO B 2 129 ? -48.829 25.753  -0.366  1.00 41.26  ? 123 PRO H N   1 
ATOM   2522 C CA  . PRO B 2 129 ? -48.421 27.108  0.018   1.00 41.59  ? 123 PRO H CA  1 
ATOM   2523 C C   . PRO B 2 129 ? -47.791 27.141  1.401   1.00 34.17  ? 123 PRO H C   1 
ATOM   2524 O O   . PRO B 2 129 ? -48.126 26.349  2.286   1.00 32.49  ? 123 PRO H O   1 
ATOM   2525 C CB  . PRO B 2 129 ? -49.737 27.898  -0.004  1.00 40.62  ? 123 PRO H CB  1 
ATOM   2526 C CG  . PRO B 2 129 ? -50.712 27.034  -0.757  1.00 46.59  ? 123 PRO H CG  1 
ATOM   2527 C CD  . PRO B 2 129 ? -50.289 25.628  -0.491  1.00 39.41  ? 123 PRO H CD  1 
ATOM   2528 N N   . LEU B 2 130 ? -46.867 28.080  1.578   1.00 34.02  ? 124 LEU H N   1 
ATOM   2529 C CA  . LEU B 2 130 ? -46.324 28.439  2.887   1.00 40.93  ? 124 LEU H CA  1 
ATOM   2530 C C   . LEU B 2 130 ? -46.871 29.831  3.195   1.00 39.90  ? 124 LEU H C   1 
ATOM   2531 O O   . LEU B 2 130 ? -46.236 30.845  2.900   1.00 36.00  ? 124 LEU H O   1 
ATOM   2532 C CB  . LEU B 2 130 ? -44.796 28.404  2.895   1.00 34.82  ? 124 LEU H CB  1 
ATOM   2533 C CG  . LEU B 2 130 ? -44.134 27.041  2.676   1.00 32.19  ? 124 LEU H CG  1 
ATOM   2534 C CD1 . LEU B 2 130 ? -42.624 27.187  2.561   1.00 34.49  ? 124 LEU H CD1 1 
ATOM   2535 C CD2 . LEU B 2 130 ? -44.496 26.080  3.799   1.00 29.40  ? 124 LEU H CD2 1 
ATOM   2536 N N   . ALA B 2 131 ? -48.061 29.866  3.788   1.00 47.03  ? 125 ALA H N   1 
ATOM   2537 C CA  . ALA B 2 131 ? -48.795 31.115  3.921   1.00 46.20  ? 125 ALA H CA  1 
ATOM   2538 C C   . ALA B 2 131 ? -48.091 32.060  4.893   1.00 51.16  ? 125 ALA H C   1 
ATOM   2539 O O   . ALA B 2 131 ? -47.544 31.617  5.909   1.00 49.49  ? 125 ALA H O   1 
ATOM   2540 C CB  . ALA B 2 131 ? -50.221 30.847  4.399   1.00 58.21  ? 125 ALA H CB  1 
ATOM   2541 N N   . PRO B 2 132 ? -48.079 33.359  4.604   1.00 58.02  ? 126 PRO H N   1 
ATOM   2542 C CA  . PRO B 2 132 ? -47.531 34.323  5.563   1.00 59.91  ? 126 PRO H CA  1 
ATOM   2543 C C   . PRO B 2 132 ? -48.412 34.438  6.796   1.00 65.80  ? 126 PRO H C   1 
ATOM   2544 O O   . PRO B 2 132 ? -49.620 34.194  6.752   1.00 60.22  ? 126 PRO H O   1 
ATOM   2545 C CB  . PRO B 2 132 ? -47.510 35.641  4.776   1.00 65.94  ? 126 PRO H CB  1 
ATOM   2546 C CG  . PRO B 2 132 ? -47.702 35.257  3.338   1.00 55.75  ? 126 PRO H CG  1 
ATOM   2547 C CD  . PRO B 2 132 ? -48.512 34.004  3.355   1.00 61.97  ? 126 PRO H CD  1 
ATOM   2548 N N   . SER B 2 133 ? -47.787 34.817  7.908   1.00 65.75  ? 127 SER H N   1 
ATOM   2549 C CA  . SER B 2 133 ? -48.500 35.045  9.156   1.00 62.29  ? 127 SER H CA  1 
ATOM   2550 C C   . SER B 2 133 ? -47.985 36.324  9.799   1.00 72.04  ? 127 SER H C   1 
ATOM   2551 O O   . SER B 2 133 ? -46.837 36.724  9.589   1.00 81.83  ? 127 SER H O   1 
ATOM   2552 C CB  . SER B 2 133 ? -48.340 33.869  10.128  1.00 66.51  ? 127 SER H CB  1 
ATOM   2553 O OG  . SER B 2 133 ? -47.003 33.766  10.586  1.00 85.49  ? 127 SER H OG  1 
ATOM   2554 N N   . SER B 2 134 ? -48.847 36.960  10.585  1.00 73.61  ? 128 SER H N   1 
ATOM   2555 C CA  . SER B 2 134 ? -48.485 38.191  11.277  1.00 69.05  ? 128 SER H CA  1 
ATOM   2556 C C   . SER B 2 134 ? -48.593 38.020  12.789  1.00 66.78  ? 128 SER H C   1 
ATOM   2557 O O   . SER B 2 134 ? -47.980 38.765  13.553  1.00 71.17  ? 128 SER H O   1 
ATOM   2558 C CB  . SER B 2 134 ? -49.369 39.350  10.813  1.00 69.81  ? 128 SER H CB  1 
ATOM   2559 O OG  . SER B 2 134 ? -49.002 40.559  11.454  1.00 72.09  ? 128 SER H OG  1 
ATOM   2560 N N   . SER B 2 138 ? -46.185 43.832  10.668  1.00 75.64  ? 132 SER H N   1 
ATOM   2561 C CA  . SER B 2 138 ? -45.079 43.128  11.306  1.00 84.19  ? 132 SER H CA  1 
ATOM   2562 C C   . SER B 2 138 ? -43.890 44.062  11.505  1.00 83.47  ? 132 SER H C   1 
ATOM   2563 O O   . SER B 2 138 ? -44.025 45.141  12.081  1.00 84.12  ? 132 SER H O   1 
ATOM   2564 C CB  . SER B 2 138 ? -44.664 41.913  10.474  1.00 84.29  ? 132 SER H CB  1 
ATOM   2565 O OG  . SER B 2 138 ? -44.120 42.311  9.227   1.00 84.67  ? 132 SER H OG  1 
ATOM   2566 N N   . GLY B 2 139 ? -42.723 43.633  11.034  1.00 78.91  ? 133 GLY H N   1 
ATOM   2567 C CA  . GLY B 2 139 ? -41.542 44.473  11.062  1.00 75.64  ? 133 GLY H CA  1 
ATOM   2568 C C   . GLY B 2 139 ? -41.262 45.093  9.710   1.00 82.23  ? 133 GLY H C   1 
ATOM   2569 O O   . GLY B 2 139 ? -40.162 45.595  9.460   1.00 84.51  ? 133 GLY H O   1 
ATOM   2570 N N   . GLY B 2 140 ? -42.259 45.062  8.826   1.00 75.87  ? 134 GLY H N   1 
ATOM   2571 C CA  . GLY B 2 140 ? -42.105 45.531  7.468   1.00 69.04  ? 134 GLY H CA  1 
ATOM   2572 C C   . GLY B 2 140 ? -41.619 44.483  6.492   1.00 70.64  ? 134 GLY H C   1 
ATOM   2573 O O   . GLY B 2 140 ? -41.715 44.698  5.277   1.00 65.90  ? 134 GLY H O   1 
ATOM   2574 N N   . THR B 2 141 ? -41.111 43.357  6.984   1.00 77.37  ? 135 THR H N   1 
ATOM   2575 C CA  . THR B 2 141 ? -40.603 42.275  6.154   1.00 68.60  ? 135 THR H CA  1 
ATOM   2576 C C   . THR B 2 141 ? -41.479 41.045  6.341   1.00 60.87  ? 135 THR H C   1 
ATOM   2577 O O   . THR B 2 141 ? -41.735 40.626  7.475   1.00 54.01  ? 135 THR H O   1 
ATOM   2578 C CB  . THR B 2 141 ? -39.147 41.954  6.507   1.00 66.79  ? 135 THR H CB  1 
ATOM   2579 O OG1 . THR B 2 141 ? -38.280 42.929  5.912   1.00 66.93  ? 135 THR H OG1 1 
ATOM   2580 C CG2 . THR B 2 141 ? -38.762 40.566  6.018   1.00 56.51  ? 135 THR H CG2 1 
ATOM   2581 N N   . ALA B 2 142 ? -41.937 40.472  5.231   1.00 49.27  ? 136 ALA H N   1 
ATOM   2582 C CA  . ALA B 2 142 ? -42.780 39.287  5.242   1.00 40.19  ? 136 ALA H CA  1 
ATOM   2583 C C   . ALA B 2 142 ? -42.102 38.168  4.466   1.00 49.41  ? 136 ALA H C   1 
ATOM   2584 O O   . ALA B 2 142 ? -41.444 38.414  3.449   1.00 41.76  ? 136 ALA H O   1 
ATOM   2585 C CB  . ALA B 2 142 ? -44.159 39.579  4.643   1.00 47.43  ? 136 ALA H CB  1 
ATOM   2586 N N   . ALA B 2 143 ? -42.261 36.941  4.952   1.00 53.17  ? 137 ALA H N   1 
ATOM   2587 C CA  . ALA B 2 143 ? -41.689 35.759  4.323   1.00 36.36  ? 137 ALA H CA  1 
ATOM   2588 C C   . ALA B 2 143 ? -42.811 34.820  3.909   1.00 30.46  ? 137 ALA H C   1 
ATOM   2589 O O   . ALA B 2 143 ? -43.723 34.549  4.697   1.00 30.79  ? 137 ALA H O   1 
ATOM   2590 C CB  . ALA B 2 143 ? -40.718 35.045  5.268   1.00 33.15  ? 137 ALA H CB  1 
ATOM   2591 N N   . LEU B 2 144 ? -42.742 34.331  2.672   1.00 25.46  ? 138 LEU H N   1 
ATOM   2592 C CA  . LEU B 2 144 ? -43.713 33.376  2.158   1.00 32.82  ? 138 LEU H CA  1 
ATOM   2593 C C   . LEU B 2 144 ? -43.007 32.451  1.179   1.00 28.94  ? 138 LEU H C   1 
ATOM   2594 O O   . LEU B 2 144 ? -41.945 32.779  0.645   1.00 36.51  ? 138 LEU H O   1 
ATOM   2595 C CB  . LEU B 2 144 ? -44.900 34.083  1.490   1.00 41.82  ? 138 LEU H CB  1 
ATOM   2596 C CG  . LEU B 2 144 ? -44.603 35.056  0.346   1.00 33.30  ? 138 LEU H CG  1 
ATOM   2597 C CD1 . LEU B 2 144 ? -44.767 34.379  -1.006  1.00 36.54  ? 138 LEU H CD1 1 
ATOM   2598 C CD2 . LEU B 2 144 ? -45.494 36.283  0.445   1.00 41.65  ? 138 LEU H CD2 1 
ATOM   2599 N N   . GLY B 2 145 ? -43.605 31.288  0.946   1.00 27.98  ? 139 GLY H N   1 
ATOM   2600 C CA  . GLY B 2 145 ? -42.952 30.312  0.105   1.00 23.38  ? 139 GLY H CA  1 
ATOM   2601 C C   . GLY B 2 145 ? -43.876 29.210  -0.365  1.00 29.70  ? 139 GLY H C   1 
ATOM   2602 O O   . GLY B 2 145 ? -45.089 29.250  -0.147  1.00 28.13  ? 139 GLY H O   1 
ATOM   2603 N N   . CYS B 2 146 ? -43.274 28.224  -1.029  1.00 27.82  ? 140 CYS H N   1 
ATOM   2604 C CA  . CYS B 2 146 ? -43.978 27.072  -1.574  1.00 28.65  ? 140 CYS H CA  1 
ATOM   2605 C C   . CYS B 2 146 ? -43.240 25.796  -1.199  1.00 29.17  ? 140 CYS H C   1 
ATOM   2606 O O   . CYS B 2 146 ? -42.008 25.738  -1.266  1.00 28.67  ? 140 CYS H O   1 
ATOM   2607 C CB  . CYS B 2 146 ? -44.109 27.162  -3.102  1.00 37.03  ? 140 CYS H CB  1 
ATOM   2608 S SG  . CYS B 2 146 ? -45.610 27.981  -3.675  1.00 68.58  ? 140 CYS H SG  1 
ATOM   2609 N N   . LEU B 2 147 ? -43.998 24.777  -0.808  1.00 30.73  ? 141 LEU H N   1 
ATOM   2610 C CA  . LEU B 2 147 ? -43.449 23.473  -0.467  1.00 25.10  ? 141 LEU H CA  1 
ATOM   2611 C C   . LEU B 2 147 ? -43.672 22.524  -1.639  1.00 23.97  ? 141 LEU H C   1 
ATOM   2612 O O   . LEU B 2 147 ? -44.818 22.242  -2.005  1.00 34.36  ? 141 LEU H O   1 
ATOM   2613 C CB  . LEU B 2 147 ? -44.095 22.931  0.808   1.00 32.76  ? 141 LEU H CB  1 
ATOM   2614 C CG  . LEU B 2 147 ? -43.644 21.558  1.307   1.00 37.30  ? 141 LEU H CG  1 
ATOM   2615 C CD1 . LEU B 2 147 ? -42.131 21.498  1.445   1.00 27.37  ? 141 LEU H CD1 1 
ATOM   2616 C CD2 . LEU B 2 147 ? -44.314 21.239  2.632   1.00 23.24  ? 141 LEU H CD2 1 
ATOM   2617 N N   . VAL B 2 148 ? -42.580 22.038  -2.222  1.00 25.32  ? 142 VAL H N   1 
ATOM   2618 C CA  . VAL B 2 148 ? -42.613 21.138  -3.369  1.00 25.65  ? 142 VAL H CA  1 
ATOM   2619 C C   . VAL B 2 148 ? -42.193 19.766  -2.858  1.00 29.50  ? 142 VAL H C   1 
ATOM   2620 O O   . VAL B 2 148 ? -41.002 19.503  -2.656  1.00 33.21  ? 142 VAL H O   1 
ATOM   2621 C CB  . VAL B 2 148 ? -41.703 21.625  -4.501  1.00 29.99  ? 142 VAL H CB  1 
ATOM   2622 C CG1 . VAL B 2 148 ? -41.783 20.689  -5.693  1.00 26.47  ? 142 VAL H CG1 1 
ATOM   2623 C CG2 . VAL B 2 148 ? -42.074 23.045  -4.904  1.00 22.17  ? 142 VAL H CG2 1 
ATOM   2624 N N   . LYS B 2 149 ? -43.165 18.880  -2.656  1.00 25.26  ? 143 LYS H N   1 
ATOM   2625 C CA  . LYS B 2 149 ? -42.958 17.653  -1.901  1.00 33.49  ? 143 LYS H CA  1 
ATOM   2626 C C   . LYS B 2 149 ? -43.269 16.426  -2.749  1.00 31.28  ? 143 LYS H C   1 
ATOM   2627 O O   . LYS B 2 149 ? -44.170 16.453  -3.593  1.00 35.36  ? 143 LYS H O   1 
ATOM   2628 C CB  . LYS B 2 149 ? -43.831 17.654  -0.637  1.00 33.37  ? 143 LYS H CB  1 
ATOM   2629 C CG  . LYS B 2 149 ? -43.430 16.632  0.411   1.00 41.84  ? 143 LYS H CG  1 
ATOM   2630 C CD  . LYS B 2 149 ? -44.332 16.723  1.632   1.00 53.28  ? 143 LYS H CD  1 
ATOM   2631 C CE  . LYS B 2 149 ? -43.927 15.724  2.703   1.00 47.98  ? 143 LYS H CE  1 
ATOM   2632 N NZ  . LYS B 2 149 ? -44.027 14.318  2.222   1.00 43.24  ? 143 LYS H NZ  1 
ATOM   2633 N N   . ASP B 2 150 ? -42.507 15.355  -2.511  1.00 33.94  ? 144 ASP H N   1 
ATOM   2634 C CA  . ASP B 2 150 ? -42.777 14.020  -3.055  1.00 35.27  ? 144 ASP H CA  1 
ATOM   2635 C C   . ASP B 2 150 ? -42.765 14.008  -4.586  1.00 38.26  ? 144 ASP H C   1 
ATOM   2636 O O   . ASP B 2 150 ? -43.776 13.750  -5.242  1.00 45.90  ? 144 ASP H O   1 
ATOM   2637 C CB  . ASP B 2 150 ? -44.104 13.478  -2.512  1.00 37.16  ? 144 ASP H CB  1 
ATOM   2638 C CG  . ASP B 2 150 ? -44.145 13.448  -0.997  1.00 45.41  ? 144 ASP H CG  1 
ATOM   2639 O OD1 . ASP B 2 150 ? -43.217 12.874  -0.391  1.00 44.79  ? 144 ASP H OD1 1 
ATOM   2640 O OD2 . ASP B 2 150 ? -45.101 14.006  -0.414  1.00 60.17  ? 144 ASP H OD2 1 
ATOM   2641 N N   . TYR B 2 151 ? -41.591 14.287  -5.151  1.00 29.08  ? 145 TYR H N   1 
ATOM   2642 C CA  . TYR B 2 151 ? -41.383 14.175  -6.587  1.00 25.30  ? 145 TYR H CA  1 
ATOM   2643 C C   . TYR B 2 151 ? -40.143 13.335  -6.869  1.00 24.60  ? 145 TYR H C   1 
ATOM   2644 O O   . TYR B 2 151 ? -39.250 13.200  -6.028  1.00 27.33  ? 145 TYR H O   1 
ATOM   2645 C CB  . TYR B 2 151 ? -41.250 15.552  -7.262  1.00 24.06  ? 145 TYR H CB  1 
ATOM   2646 C CG  . TYR B 2 151 ? -39.985 16.313  -6.923  1.00 24.93  ? 145 TYR H CG  1 
ATOM   2647 C CD1 . TYR B 2 151 ? -38.829 16.155  -7.680  1.00 24.52  ? 145 TYR H CD1 1 
ATOM   2648 C CD2 . TYR B 2 151 ? -39.953 17.203  -5.858  1.00 22.43  ? 145 TYR H CD2 1 
ATOM   2649 C CE1 . TYR B 2 151 ? -37.675 16.851  -7.375  1.00 24.76  ? 145 TYR H CE1 1 
ATOM   2650 C CE2 . TYR B 2 151 ? -38.804 17.906  -5.548  1.00 19.38  ? 145 TYR H CE2 1 
ATOM   2651 C CZ  . TYR B 2 151 ? -37.669 17.726  -6.310  1.00 28.21  ? 145 TYR H CZ  1 
ATOM   2652 O OH  . TYR B 2 151 ? -36.521 18.421  -6.008  1.00 30.93  ? 145 TYR H OH  1 
ATOM   2653 N N   . PHE B 2 152 ? -40.105 12.763  -8.075  1.00 29.66  ? 146 PHE H N   1 
ATOM   2654 C CA  . PHE B 2 152 ? -38.956 11.998  -8.538  1.00 26.37  ? 146 PHE H CA  1 
ATOM   2655 C C   . PHE B 2 152 ? -38.999 11.950  -10.053 1.00 28.98  ? 146 PHE H C   1 
ATOM   2656 O O   . PHE B 2 152 ? -40.085 11.764  -10.618 1.00 32.06  ? 146 PHE H O   1 
ATOM   2657 C CB  . PHE B 2 152 ? -38.952 10.577  -7.962  1.00 25.43  ? 146 PHE H CB  1 
ATOM   2658 C CG  . PHE B 2 152 ? -37.758 9.757   -8.372  1.00 29.37  ? 146 PHE H CG  1 
ATOM   2659 C CD1 . PHE B 2 152 ? -36.578 9.818   -7.649  1.00 23.17  ? 146 PHE H CD1 1 
ATOM   2660 C CD2 . PHE B 2 152 ? -37.816 8.924   -9.479  1.00 29.99  ? 146 PHE H CD2 1 
ATOM   2661 C CE1 . PHE B 2 152 ? -35.478 9.067   -8.023  1.00 28.54  ? 146 PHE H CE1 1 
ATOM   2662 C CE2 . PHE B 2 152 ? -36.721 8.171   -9.858  1.00 24.03  ? 146 PHE H CE2 1 
ATOM   2663 C CZ  . PHE B 2 152 ? -35.551 8.242   -9.129  1.00 28.54  ? 146 PHE H CZ  1 
ATOM   2664 N N   . PRO B 2 153 ? -37.863 12.108  -10.743 1.00 37.23  ? 147 PRO H N   1 
ATOM   2665 C CA  . PRO B 2 153 ? -36.526 12.392  -10.214 1.00 29.67  ? 147 PRO H CA  1 
ATOM   2666 C C   . PRO B 2 153 ? -36.180 13.876  -10.257 1.00 30.24  ? 147 PRO H C   1 
ATOM   2667 O O   . PRO B 2 153 ? -37.034 14.723  -10.504 1.00 26.25  ? 147 PRO H O   1 
ATOM   2668 C CB  . PRO B 2 153 ? -35.629 11.577  -11.148 1.00 30.20  ? 147 PRO H CB  1 
ATOM   2669 C CG  . PRO B 2 153 ? -36.316 11.721  -12.484 1.00 29.54  ? 147 PRO H CG  1 
ATOM   2670 C CD  . PRO B 2 153 ? -37.805 11.773  -12.178 1.00 32.84  ? 147 PRO H CD  1 
ATOM   2671 N N   . GLU B 2 154 ? -34.916 14.205  -10.010 1.00 37.27  ? 148 GLU H N   1 
ATOM   2672 C CA  . GLU B 2 154 ? -34.446 15.567  -10.184 1.00 34.68  ? 148 GLU H CA  1 
ATOM   2673 C C   . GLU B 2 154 ? -34.457 15.936  -11.669 1.00 30.94  ? 148 GLU H C   1 
ATOM   2674 O O   . GLU B 2 154 ? -34.368 15.060  -12.533 1.00 33.11  ? 148 GLU H O   1 
ATOM   2675 C CB  . GLU B 2 154 ? -33.034 15.717  -9.619  1.00 29.02  ? 148 GLU H CB  1 
ATOM   2676 C CG  . GLU B 2 154 ? -32.928 15.539  -8.110  1.00 32.34  ? 148 GLU H CG  1 
ATOM   2677 C CD  . GLU B 2 154 ? -33.126 16.837  -7.348  1.00 40.95  ? 148 GLU H CD  1 
ATOM   2678 O OE1 . GLU B 2 154 ? -34.104 17.560  -7.633  1.00 41.46  ? 148 GLU H OE1 1 
ATOM   2679 O OE2 . GLU B 2 154 ? -32.292 17.139  -6.468  1.00 39.06  ? 148 GLU H OE2 1 
ATOM   2680 N N   . PRO B 2 155 ? -34.565 17.231  -11.996 1.00 37.00  ? 149 PRO H N   1 
ATOM   2681 C CA  . PRO B 2 155 ? -34.707 18.388  -11.111 1.00 37.48  ? 149 PRO H CA  1 
ATOM   2682 C C   . PRO B 2 155 ? -36.100 19.005  -11.137 1.00 38.47  ? 149 PRO H C   1 
ATOM   2683 O O   . PRO B 2 155 ? -36.990 18.556  -11.855 1.00 35.76  ? 149 PRO H O   1 
ATOM   2684 C CB  . PRO B 2 155 ? -33.656 19.352  -11.674 1.00 34.74  ? 149 PRO H CB  1 
ATOM   2685 C CG  . PRO B 2 155 ? -33.584 19.013  -13.176 1.00 32.09  ? 149 PRO H CG  1 
ATOM   2686 C CD  . PRO B 2 155 ? -34.286 17.676  -13.370 1.00 38.77  ? 149 PRO H CD  1 
ATOM   2687 N N   . VAL B 2 156 ? -36.303 20.049  -10.337 1.00 38.09  ? 150 VAL H N   1 
ATOM   2688 C CA  . VAL B 2 156 ? -37.531 20.833  -10.336 1.00 33.49  ? 150 VAL H CA  1 
ATOM   2689 C C   . VAL B 2 156 ? -37.151 22.301  -10.456 1.00 40.59  ? 150 VAL H C   1 
ATOM   2690 O O   . VAL B 2 156 ? -36.271 22.779  -9.732  1.00 47.67  ? 150 VAL H O   1 
ATOM   2691 C CB  . VAL B 2 156 ? -38.371 20.587  -9.068  1.00 19.39  ? 150 VAL H CB  1 
ATOM   2692 C CG1 . VAL B 2 156 ? -39.243 21.792  -8.755  1.00 33.18  ? 150 VAL H CG1 1 
ATOM   2693 C CG2 . VAL B 2 156 ? -39.236 19.354  -9.244  1.00 34.24  ? 150 VAL H CG2 1 
ATOM   2694 N N   . THR B 2 157 ? -37.801 23.008  -11.375 1.00 28.34  ? 151 THR H N   1 
ATOM   2695 C CA  . THR B 2 157 ? -37.624 24.445  -11.527 1.00 36.33  ? 151 THR H CA  1 
ATOM   2696 C C   . THR B 2 157 ? -38.757 25.169  -10.811 1.00 36.42  ? 151 THR H C   1 
ATOM   2697 O O   . THR B 2 157 ? -39.930 24.823  -10.985 1.00 32.09  ? 151 THR H O   1 
ATOM   2698 C CB  . THR B 2 157 ? -37.588 24.845  -13.003 1.00 38.97  ? 151 THR H CB  1 
ATOM   2699 O OG1 . THR B 2 157 ? -38.522 24.047  -13.741 1.00 52.15  ? 151 THR H OG1 1 
ATOM   2700 C CG2 . THR B 2 157 ? -36.191 24.652  -13.575 1.00 25.78  ? 151 THR H CG2 1 
ATOM   2701 N N   . VAL B 2 158 ? -38.401 26.159  -9.996  1.00 35.71  ? 152 VAL H N   1 
ATOM   2702 C CA  . VAL B 2 158 ? -39.367 26.954  -9.249  1.00 28.30  ? 152 VAL H CA  1 
ATOM   2703 C C   . VAL B 2 158 ? -39.114 28.422  -9.552  1.00 32.07  ? 152 VAL H C   1 
ATOM   2704 O O   . VAL B 2 158 ? -37.975 28.893  -9.455  1.00 34.63  ? 152 VAL H O   1 
ATOM   2705 C CB  . VAL B 2 158 ? -39.280 26.693  -7.732  1.00 33.70  ? 152 VAL H CB  1 
ATOM   2706 C CG1 . VAL B 2 158 ? -40.324 27.517  -6.993  1.00 30.43  ? 152 VAL H CG1 1 
ATOM   2707 C CG2 . VAL B 2 158 ? -39.457 25.214  -7.433  1.00 26.40  ? 152 VAL H CG2 1 
ATOM   2708 N N   . SER B 2 159 ? -40.172 29.141  -9.922  1.00 38.88  ? 153 SER H N   1 
ATOM   2709 C CA  . SER B 2 159 ? -40.090 30.567  -10.196 1.00 39.73  ? 153 SER H CA  1 
ATOM   2710 C C   . SER B 2 159 ? -41.288 31.260  -9.564  1.00 36.25  ? 153 SER H C   1 
ATOM   2711 O O   . SER B 2 159 ? -42.324 30.643  -9.304  1.00 38.40  ? 153 SER H O   1 
ATOM   2712 C CB  . SER B 2 159 ? -40.034 30.853  -11.702 1.00 36.24  ? 153 SER H CB  1 
ATOM   2713 O OG  . SER B 2 159 ? -41.097 30.210  -12.383 1.00 34.60  ? 153 SER H OG  1 
ATOM   2714 N N   . TRP B 2 160 ? -41.134 32.557  -9.313  1.00 30.24  ? 154 TRP H N   1 
ATOM   2715 C CA  . TRP B 2 160 ? -42.160 33.359  -8.662  1.00 40.92  ? 154 TRP H CA  1 
ATOM   2716 C C   . TRP B 2 160 ? -42.653 34.439  -9.614  1.00 40.65  ? 154 TRP H C   1 
ATOM   2717 O O   . TRP B 2 160 ? -41.847 35.166  -10.205 1.00 34.46  ? 154 TRP H O   1 
ATOM   2718 C CB  . TRP B 2 160 ? -41.628 33.980  -7.369  1.00 35.66  ? 154 TRP H CB  1 
ATOM   2719 C CG  . TRP B 2 160 ? -41.469 32.976  -6.274  1.00 34.27  ? 154 TRP H CG  1 
ATOM   2720 C CD1 . TRP B 2 160 ? -40.377 32.196  -6.026  1.00 36.42  ? 154 TRP H CD1 1 
ATOM   2721 C CD2 . TRP B 2 160 ? -42.442 32.632  -5.281  1.00 43.60  ? 154 TRP H CD2 1 
ATOM   2722 N NE1 . TRP B 2 160 ? -40.608 31.391  -4.937  1.00 33.68  ? 154 TRP H NE1 1 
ATOM   2723 C CE2 . TRP B 2 160 ? -41.869 31.638  -4.463  1.00 44.46  ? 154 TRP H CE2 1 
ATOM   2724 C CE3 . TRP B 2 160 ? -43.741 33.069  -5.004  1.00 45.86  ? 154 TRP H CE3 1 
ATOM   2725 C CZ2 . TRP B 2 160 ? -42.549 31.077  -3.384  1.00 33.42  ? 154 TRP H CZ2 1 
ATOM   2726 C CZ3 . TRP B 2 160 ? -44.415 32.509  -3.936  1.00 43.77  ? 154 TRP H CZ3 1 
ATOM   2727 C CH2 . TRP B 2 160 ? -43.818 31.525  -3.138  1.00 50.77  ? 154 TRP H CH2 1 
ATOM   2728 N N   . ASN B 2 161 ? -43.976 34.538  -9.747  1.00 46.24  ? 155 ASN H N   1 
ATOM   2729 C CA  . ASN B 2 161 ? -44.625 35.494  -10.643 1.00 32.54  ? 155 ASN H CA  1 
ATOM   2730 C C   . ASN B 2 161 ? -44.103 35.350  -12.071 1.00 37.41  ? 155 ASN H C   1 
ATOM   2731 O O   . ASN B 2 161 ? -43.765 36.328  -12.741 1.00 38.84  ? 155 ASN H O   1 
ATOM   2732 C CB  . ASN B 2 161 ? -44.459 36.927  -10.133 1.00 32.99  ? 155 ASN H CB  1 
ATOM   2733 C CG  . ASN B 2 161 ? -45.146 37.152  -8.799  1.00 38.21  ? 155 ASN H CG  1 
ATOM   2734 O OD1 . ASN B 2 161 ? -45.986 36.356  -8.378  1.00 33.96  ? 155 ASN H OD1 1 
ATOM   2735 N ND2 . ASN B 2 161 ? -44.797 38.246  -8.131  1.00 35.44  ? 155 ASN H ND2 1 
ATOM   2736 N N   . SER B 2 162 ? -44.034 34.098  -12.529 1.00 33.70  ? 156 SER H N   1 
ATOM   2737 C CA  . SER B 2 162 ? -43.608 33.768  -13.891 1.00 38.19  ? 156 SER H CA  1 
ATOM   2738 C C   . SER B 2 162 ? -42.217 34.322  -14.195 1.00 42.20  ? 156 SER H C   1 
ATOM   2739 O O   . SER B 2 162 ? -41.941 34.785  -15.304 1.00 45.04  ? 156 SER H O   1 
ATOM   2740 C CB  . SER B 2 162 ? -44.630 34.258  -14.920 1.00 43.70  ? 156 SER H CB  1 
ATOM   2741 O OG  . SER B 2 162 ? -45.914 33.718  -14.659 1.00 38.24  ? 156 SER H OG  1 
ATOM   2742 N N   . GLY B 2 163 ? -41.332 34.268  -13.202 1.00 40.81  ? 157 GLY H N   1 
ATOM   2743 C CA  . GLY B 2 163 ? -39.962 34.704  -13.367 1.00 40.97  ? 157 GLY H CA  1 
ATOM   2744 C C   . GLY B 2 163 ? -39.701 36.169  -13.092 1.00 46.64  ? 157 GLY H C   1 
ATOM   2745 O O   . GLY B 2 163 ? -38.539 36.593  -13.145 1.00 49.70  ? 157 GLY H O   1 
ATOM   2746 N N   . ALA B 2 164 ? -40.738 36.958  -12.800 1.00 48.24  ? 158 ALA H N   1 
ATOM   2747 C CA  . ALA B 2 164 ? -40.546 38.381  -12.545 1.00 38.65  ? 158 ALA H CA  1 
ATOM   2748 C C   . ALA B 2 164 ? -39.927 38.639  -11.176 1.00 45.36  ? 158 ALA H C   1 
ATOM   2749 O O   . ALA B 2 164 ? -39.104 39.549  -11.026 1.00 46.51  ? 158 ALA H O   1 
ATOM   2750 C CB  . ALA B 2 164 ? -41.878 39.118  -12.666 1.00 45.23  ? 158 ALA H CB  1 
ATOM   2751 N N   . LEU B 2 165 ? -40.306 37.855  -10.169 1.00 50.83  ? 159 LEU H N   1 
ATOM   2752 C CA  . LEU B 2 165 ? -39.832 38.056  -8.804  1.00 44.73  ? 159 LEU H CA  1 
ATOM   2753 C C   . LEU B 2 165 ? -38.569 37.228  -8.595  1.00 39.98  ? 159 LEU H C   1 
ATOM   2754 O O   . LEU B 2 165 ? -38.612 35.994  -8.631  1.00 49.19  ? 159 LEU H O   1 
ATOM   2755 C CB  . LEU B 2 165 ? -40.917 37.679  -7.800  1.00 36.46  ? 159 LEU H CB  1 
ATOM   2756 C CG  . LEU B 2 165 ? -40.620 37.937  -6.324  1.00 43.50  ? 159 LEU H CG  1 
ATOM   2757 C CD1 . LEU B 2 165 ? -40.220 39.386  -6.103  1.00 45.22  ? 159 LEU H CD1 1 
ATOM   2758 C CD2 . LEU B 2 165 ? -41.837 37.587  -5.491  1.00 43.76  ? 159 LEU H CD2 1 
ATOM   2759 N N   . THR B 2 166 ? -37.449 37.906  -8.375  1.00 38.72  ? 160 THR H N   1 
ATOM   2760 C CA  . THR B 2 166 ? -36.153 37.266  -8.173  1.00 41.22  ? 160 THR H CA  1 
ATOM   2761 C C   . THR B 2 166 ? -35.460 37.720  -6.897  1.00 40.71  ? 160 THR H C   1 
ATOM   2762 O O   . THR B 2 166 ? -34.821 36.903  -6.227  1.00 41.17  ? 160 THR H O   1 
ATOM   2763 C CB  . THR B 2 166 ? -35.252 37.532  -9.402  1.00 50.66  ? 160 THR H CB  1 
ATOM   2764 O OG1 . THR B 2 166 ? -35.596 36.621  -10.453 1.00 46.87  ? 160 THR H OG1 1 
ATOM   2765 C CG2 . THR B 2 166 ? -33.774 37.374  -9.060  1.00 52.12  ? 160 THR H CG2 1 
ATOM   2766 N N   . SER B 2 167 ? -35.588 38.993  -6.530  1.00 44.26  ? 161 SER H N   1 
ATOM   2767 C CA  . SER B 2 167 ? -34.938 39.499  -5.329  1.00 47.61  ? 161 SER H CA  1 
ATOM   2768 C C   . SER B 2 167 ? -35.540 38.855  -4.085  1.00 40.55  ? 161 SER H C   1 
ATOM   2769 O O   . SER B 2 167 ? -36.764 38.803  -3.928  1.00 37.77  ? 161 SER H O   1 
ATOM   2770 C CB  . SER B 2 167 ? -35.070 41.019  -5.256  1.00 49.55  ? 161 SER H CB  1 
ATOM   2771 O OG  . SER B 2 167 ? -34.479 41.528  -4.072  1.00 52.33  ? 161 SER H OG  1 
ATOM   2772 N N   . GLY B 2 168 ? -34.674 38.371  -3.197  1.00 46.28  ? 162 GLY H N   1 
ATOM   2773 C CA  . GLY B 2 168 ? -35.114 37.735  -1.972  1.00 41.78  ? 162 GLY H CA  1 
ATOM   2774 C C   . GLY B 2 168 ? -35.579 36.304  -2.113  1.00 44.60  ? 162 GLY H C   1 
ATOM   2775 O O   . GLY B 2 168 ? -36.178 35.771  -1.173  1.00 39.93  ? 162 GLY H O   1 
ATOM   2776 N N   . VAL B 2 169 ? -35.320 35.662  -3.246  1.00 36.79  ? 163 VAL H N   1 
ATOM   2777 C CA  . VAL B 2 169 ? -35.791 34.305  -3.494  1.00 31.44  ? 163 VAL H CA  1 
ATOM   2778 C C   . VAL B 2 169 ? -34.692 33.319  -3.121  1.00 37.21  ? 163 VAL H C   1 
ATOM   2779 O O   . VAL B 2 169 ? -33.556 33.427  -3.599  1.00 33.25  ? 163 VAL H O   1 
ATOM   2780 C CB  . VAL B 2 169 ? -36.213 34.129  -4.962  1.00 25.06  ? 163 VAL H CB  1 
ATOM   2781 C CG1 . VAL B 2 169 ? -36.598 32.682  -5.228  1.00 30.19  ? 163 VAL H CG1 1 
ATOM   2782 C CG2 . VAL B 2 169 ? -37.366 35.063  -5.294  1.00 33.78  ? 163 VAL H CG2 1 
ATOM   2783 N N   . HIS B 2 170 ? -35.027 32.362  -2.257  1.00 32.46  ? 164 HIS H N   1 
ATOM   2784 C CA  . HIS B 2 170 ? -34.127 31.274  -1.886  1.00 25.90  ? 164 HIS H CA  1 
ATOM   2785 C C   . HIS B 2 170 ? -34.820 29.954  -2.195  1.00 23.14  ? 164 HIS H C   1 
ATOM   2786 O O   . HIS B 2 170 ? -35.764 29.565  -1.498  1.00 25.04  ? 164 HIS H O   1 
ATOM   2787 C CB  . HIS B 2 170 ? -33.736 31.351  -0.410  1.00 23.24  ? 164 HIS H CB  1 
ATOM   2788 C CG  . HIS B 2 170 ? -32.891 32.537  -0.065  1.00 24.87  ? 164 HIS H CG  1 
ATOM   2789 N ND1 . HIS B 2 170 ? -31.593 32.680  -0.505  1.00 24.15  ? 164 HIS H ND1 1 
ATOM   2790 C CD2 . HIS B 2 170 ? -33.156 33.631  0.689   1.00 27.29  ? 164 HIS H CD2 1 
ATOM   2791 C CE1 . HIS B 2 170 ? -31.096 33.814  -0.043  1.00 33.03  ? 164 HIS H CE1 1 
ATOM   2792 N NE2 . HIS B 2 170 ? -32.024 34.409  0.685   1.00 38.62  ? 164 HIS H NE2 1 
ATOM   2793 N N   . THR B 2 171 ? -34.354 29.266  -3.235  1.00 13.81  ? 165 THR H N   1 
ATOM   2794 C CA  . THR B 2 171 ? -34.848 27.940  -3.588  1.00 24.61  ? 165 THR H CA  1 
ATOM   2795 C C   . THR B 2 171 ? -33.854 26.915  -3.053  1.00 26.17  ? 165 THR H C   1 
ATOM   2796 O O   . THR B 2 171 ? -32.745 26.779  -3.581  1.00 25.69  ? 165 THR H O   1 
ATOM   2797 C CB  . THR B 2 171 ? -35.033 27.801  -5.098  1.00 17.35  ? 165 THR H CB  1 
ATOM   2798 O OG1 . THR B 2 171 ? -35.980 28.774  -5.557  1.00 27.82  ? 165 THR H OG1 1 
ATOM   2799 C CG2 . THR B 2 171 ? -35.541 26.410  -5.446  1.00 18.36  ? 165 THR H CG2 1 
ATOM   2800 N N   . PHE B 2 172 ? -34.254 26.197  -2.008  1.00 19.72  ? 166 PHE H N   1 
ATOM   2801 C CA  . PHE B 2 172 ? -33.335 25.319  -1.306  1.00 23.93  ? 166 PHE H CA  1 
ATOM   2802 C C   . PHE B 2 172 ? -33.038 24.063  -2.125  1.00 25.65  ? 166 PHE H C   1 
ATOM   2803 O O   . PHE B 2 172 ? -33.881 23.600  -2.898  1.00 29.92  ? 166 PHE H O   1 
ATOM   2804 C CB  . PHE B 2 172 ? -33.909 24.929  0.051   1.00 22.81  ? 166 PHE H CB  1 
ATOM   2805 C CG  . PHE B 2 172 ? -34.045 26.082  0.997   1.00 18.84  ? 166 PHE H CG  1 
ATOM   2806 C CD1 . PHE B 2 172 ? -32.979 26.468  1.791   1.00 17.40  ? 166 PHE H CD1 1 
ATOM   2807 C CD2 . PHE B 2 172 ? -35.232 26.787  1.085   1.00 15.76  ? 166 PHE H CD2 1 
ATOM   2808 C CE1 . PHE B 2 172 ? -33.097 27.534  2.662   1.00 21.48  ? 166 PHE H CE1 1 
ATOM   2809 C CE2 . PHE B 2 172 ? -35.357 27.853  1.953   1.00 21.52  ? 166 PHE H CE2 1 
ATOM   2810 C CZ  . PHE B 2 172 ? -34.287 28.227  2.743   1.00 25.56  ? 166 PHE H CZ  1 
ATOM   2811 N N   . PRO B 2 173 ? -31.837 23.502  -1.980  1.00 20.46  ? 167 PRO H N   1 
ATOM   2812 C CA  . PRO B 2 173 ? -31.538 22.226  -2.638  1.00 20.36  ? 167 PRO H CA  1 
ATOM   2813 C C   . PRO B 2 173 ? -32.460 21.125  -2.139  1.00 22.75  ? 167 PRO H C   1 
ATOM   2814 O O   . PRO B 2 173 ? -32.866 21.102  -0.974  1.00 22.50  ? 167 PRO H O   1 
ATOM   2815 C CB  . PRO B 2 173 ? -30.079 21.956  -2.248  1.00 18.65  ? 167 PRO H CB  1 
ATOM   2816 C CG  . PRO B 2 173 ? -29.526 23.295  -1.876  1.00 25.47  ? 167 PRO H CG  1 
ATOM   2817 C CD  . PRO B 2 173 ? -30.670 24.045  -1.266  1.00 23.20  ? 167 PRO H CD  1 
ATOM   2818 N N   . ALA B 2 174 ? -32.797 20.210  -3.042  1.00 27.47  ? 168 ALA H N   1 
ATOM   2819 C CA  . ALA B 2 174 ? -33.699 19.122  -2.700  1.00 26.70  ? 168 ALA H CA  1 
ATOM   2820 C C   . ALA B 2 174 ? -33.068 18.194  -1.668  1.00 29.01  ? 168 ALA H C   1 
ATOM   2821 O O   . ALA B 2 174 ? -31.849 18.007  -1.627  1.00 29.11  ? 168 ALA H O   1 
ATOM   2822 C CB  . ALA B 2 174 ? -34.076 18.328  -3.949  1.00 21.81  ? 168 ALA H CB  1 
ATOM   2823 N N   . VAL B 2 175 ? -33.917 17.615  -0.824  1.00 26.85  ? 169 VAL H N   1 
ATOM   2824 C CA  . VAL B 2 175 ? -33.510 16.613  0.153   1.00 31.18  ? 169 VAL H CA  1 
ATOM   2825 C C   . VAL B 2 175 ? -34.188 15.300  -0.211  1.00 26.84  ? 169 VAL H C   1 
ATOM   2826 O O   . VAL B 2 175 ? -35.389 15.274  -0.506  1.00 27.25  ? 169 VAL H O   1 
ATOM   2827 C CB  . VAL B 2 175 ? -33.855 17.038  1.594   1.00 27.72  ? 169 VAL H CB  1 
ATOM   2828 C CG1 . VAL B 2 175 ? -32.984 18.208  2.022   1.00 25.76  ? 169 VAL H CG1 1 
ATOM   2829 C CG2 . VAL B 2 175 ? -35.328 17.401  1.716   1.00 35.17  ? 169 VAL H CG2 1 
ATOM   2830 N N   . LEU B 2 176 ? -33.414 14.219  -0.218  1.00 32.91  ? 170 LEU H N   1 
ATOM   2831 C CA  . LEU B 2 176 ? -33.952 12.906  -0.545  1.00 24.79  ? 170 LEU H CA  1 
ATOM   2832 C C   . LEU B 2 176 ? -34.596 12.305  0.698   1.00 28.37  ? 170 LEU H C   1 
ATOM   2833 O O   . LEU B 2 176 ? -33.924 12.094  1.713   1.00 33.09  ? 170 LEU H O   1 
ATOM   2834 C CB  . LEU B 2 176 ? -32.854 11.995  -1.086  1.00 26.50  ? 170 LEU H CB  1 
ATOM   2835 C CG  . LEU B 2 176 ? -33.312 10.617  -1.565  1.00 25.64  ? 170 LEU H CG  1 
ATOM   2836 C CD1 . LEU B 2 176 ? -34.462 10.753  -2.552  1.00 24.99  ? 170 LEU H CD1 1 
ATOM   2837 C CD2 . LEU B 2 176 ? -32.156 9.855   -2.192  1.00 20.36  ? 170 LEU H CD2 1 
ATOM   2838 N N   . GLN B 2 177 ? -35.894 12.038  0.618   1.00 27.65  ? 171 GLN H N   1 
ATOM   2839 C CA  . GLN B 2 177 ? -36.625 11.477  1.740   1.00 31.00  ? 171 GLN H CA  1 
ATOM   2840 C C   . GLN B 2 177 ? -36.403 9.969   1.821   1.00 33.20  ? 171 GLN H C   1 
ATOM   2841 O O   . GLN B 2 177 ? -35.945 9.328   0.870   1.00 30.49  ? 171 GLN H O   1 
ATOM   2842 C CB  . GLN B 2 177 ? -38.116 11.789  1.612   1.00 29.75  ? 171 GLN H CB  1 
ATOM   2843 C CG  . GLN B 2 177 ? -38.409 13.255  1.333   1.00 31.60  ? 171 GLN H CG  1 
ATOM   2844 C CD  . GLN B 2 177 ? -39.886 13.528  1.127   1.00 53.59  ? 171 GLN H CD  1 
ATOM   2845 O OE1 . GLN B 2 177 ? -40.395 13.440  0.009   1.00 46.15  ? 171 GLN H OE1 1 
ATOM   2846 N NE2 . GLN B 2 177 ? -40.582 13.862  2.208   1.00 56.74  ? 171 GLN H NE2 1 
ATOM   2847 N N   . SER B 2 178 ? -36.737 9.402   2.984   1.00 34.22  ? 172 SER H N   1 
ATOM   2848 C CA  . SER B 2 178 ? -36.579 7.965   3.183   1.00 36.05  ? 172 SER H CA  1 
ATOM   2849 C C   . SER B 2 178 ? -37.461 7.153   2.244   1.00 33.46  ? 172 SER H C   1 
ATOM   2850 O O   . SER B 2 178 ? -37.199 5.963   2.038   1.00 33.96  ? 172 SER H O   1 
ATOM   2851 C CB  . SER B 2 178 ? -36.885 7.598   4.635   1.00 34.37  ? 172 SER H CB  1 
ATOM   2852 O OG  . SER B 2 178 ? -38.218 7.936   4.975   1.00 36.96  ? 172 SER H OG  1 
ATOM   2853 N N   . SER B 2 179 ? -38.496 7.767   1.670   1.00 27.05  ? 173 SER H N   1 
ATOM   2854 C CA  . SER B 2 179 ? -39.346 7.099   0.696   1.00 30.58  ? 173 SER H CA  1 
ATOM   2855 C C   . SER B 2 179 ? -38.705 7.000   -0.682  1.00 32.37  ? 173 SER H C   1 
ATOM   2856 O O   . SER B 2 179 ? -39.278 6.356   -1.568  1.00 39.10  ? 173 SER H O   1 
ATOM   2857 C CB  . SER B 2 179 ? -40.687 7.829   0.580   1.00 23.28  ? 173 SER H CB  1 
ATOM   2858 O OG  . SER B 2 179 ? -40.515 9.122   0.024   1.00 28.31  ? 173 SER H OG  1 
ATOM   2859 N N   . GLY B 2 180 ? -37.543 7.617   -0.883  1.00 27.29  ? 174 GLY H N   1 
ATOM   2860 C CA  . GLY B 2 180 ? -36.922 7.677   -2.188  1.00 25.69  ? 174 GLY H CA  1 
ATOM   2861 C C   . GLY B 2 180 ? -37.360 8.844   -3.044  1.00 30.20  ? 174 GLY H C   1 
ATOM   2862 O O   . GLY B 2 180 ? -36.868 8.984   -4.171  1.00 29.50  ? 174 GLY H O   1 
ATOM   2863 N N   . LEU B 2 181 ? -38.265 9.681   -2.550  1.00 26.65  ? 175 LEU H N   1 
ATOM   2864 C CA  . LEU B 2 181 ? -38.744 10.852  -3.265  1.00 28.21  ? 175 LEU H CA  1 
ATOM   2865 C C   . LEU B 2 181 ? -38.029 12.102  -2.766  1.00 29.12  ? 175 LEU H C   1 
ATOM   2866 O O   . LEU B 2 181 ? -37.511 12.148  -1.648  1.00 29.99  ? 175 LEU H O   1 
ATOM   2867 C CB  . LEU B 2 181 ? -40.256 11.006  -3.091  1.00 25.04  ? 175 LEU H CB  1 
ATOM   2868 C CG  . LEU B 2 181 ? -41.084 9.763   -3.422  1.00 31.73  ? 175 LEU H CG  1 
ATOM   2869 C CD1 . LEU B 2 181 ? -42.551 9.994   -3.096  1.00 23.79  ? 175 LEU H CD1 1 
ATOM   2870 C CD2 . LEU B 2 181 ? -40.909 9.378   -4.882  1.00 26.51  ? 175 LEU H CD2 1 
ATOM   2871 N N   . TYR B 2 182 ? -38.007 13.124  -3.615  1.00 23.87  ? 176 TYR H N   1 
ATOM   2872 C CA  . TYR B 2 182 ? -37.352 14.383  -3.297  1.00 24.50  ? 176 TYR H CA  1 
ATOM   2873 C C   . TYR B 2 182 ? -38.370 15.408  -2.811  1.00 22.14  ? 176 TYR H C   1 
ATOM   2874 O O   . TYR B 2 182 ? -39.524 15.420  -3.244  1.00 28.73  ? 176 TYR H O   1 
ATOM   2875 C CB  . TYR B 2 182 ? -36.602 14.935  -4.511  1.00 28.24  ? 176 TYR H CB  1 
ATOM   2876 C CG  . TYR B 2 182 ? -35.407 14.109  -4.929  1.00 27.78  ? 176 TYR H CG  1 
ATOM   2877 C CD1 . TYR B 2 182 ? -34.169 14.290  -4.324  1.00 23.43  ? 176 TYR H CD1 1 
ATOM   2878 C CD2 . TYR B 2 182 ? -35.514 13.152  -5.930  1.00 20.03  ? 176 TYR H CD2 1 
ATOM   2879 C CE1 . TYR B 2 182 ? -33.073 13.540  -4.702  1.00 19.57  ? 176 TYR H CE1 1 
ATOM   2880 C CE2 . TYR B 2 182 ? -34.422 12.396  -6.315  1.00 21.93  ? 176 TYR H CE2 1 
ATOM   2881 C CZ  . TYR B 2 182 ? -33.204 12.595  -5.698  1.00 25.76  ? 176 TYR H CZ  1 
ATOM   2882 O OH  . TYR B 2 182 ? -32.113 11.846  -6.075  1.00 23.46  ? 176 TYR H OH  1 
ATOM   2883 N N   . SER B 2 183 ? -37.925 16.267  -1.897  1.00 26.43  ? 177 SER H N   1 
ATOM   2884 C CA  . SER B 2 183 ? -38.732 17.358  -1.374  1.00 27.23  ? 177 SER H CA  1 
ATOM   2885 C C   . SER B 2 183 ? -37.924 18.646  -1.431  1.00 29.29  ? 177 SER H C   1 
ATOM   2886 O O   . SER B 2 183 ? -36.693 18.629  -1.337  1.00 25.90  ? 177 SER H O   1 
ATOM   2887 C CB  . SER B 2 183 ? -39.192 17.085  0.065   1.00 34.84  ? 177 SER H CB  1 
ATOM   2888 O OG  . SER B 2 183 ? -39.952 18.169  0.571   1.00 41.84  ? 177 SER H OG  1 
ATOM   2889 N N   . LEU B 2 184 ? -38.627 19.766  -1.583  1.00 23.88  ? 178 LEU H N   1 
ATOM   2890 C CA  . LEU B 2 184 ? -37.972 21.042  -1.826  1.00 24.07  ? 178 LEU H CA  1 
ATOM   2891 C C   . LEU B 2 184 ? -38.862 22.174  -1.335  1.00 27.99  ? 178 LEU H C   1 
ATOM   2892 O O   . LEU B 2 184 ? -40.088 22.042  -1.282  1.00 28.54  ? 178 LEU H O   1 
ATOM   2893 C CB  . LEU B 2 184 ? -37.650 21.204  -3.320  1.00 26.51  ? 178 LEU H CB  1 
ATOM   2894 C CG  . LEU B 2 184 ? -36.952 22.454  -3.857  1.00 35.46  ? 178 LEU H CG  1 
ATOM   2895 C CD1 . LEU B 2 184 ? -36.077 22.080  -5.040  1.00 29.24  ? 178 LEU H CD1 1 
ATOM   2896 C CD2 . LEU B 2 184 ? -37.964 23.512  -4.271  1.00 19.13  ? 178 LEU H CD2 1 
ATOM   2897 N N   . SER B 2 185 ? -38.229 23.288  -0.970  1.00 19.91  ? 179 SER H N   1 
ATOM   2898 C CA  . SER B 2 185 ? -38.929 24.504  -0.586  1.00 27.90  ? 179 SER H CA  1 
ATOM   2899 C C   . SER B 2 185 ? -38.274 25.706  -1.250  1.00 29.55  ? 179 SER H C   1 
ATOM   2900 O O   . SER B 2 185 ? -37.063 25.723  -1.489  1.00 24.93  ? 179 SER H O   1 
ATOM   2901 C CB  . SER B 2 185 ? -38.940 24.702  0.937   1.00 18.98  ? 179 SER H CB  1 
ATOM   2902 O OG  . SER B 2 185 ? -39.859 23.825  1.562   1.00 33.38  ? 179 SER H OG  1 
ATOM   2903 N N   . SER B 2 186 ? -39.094 26.711  -1.552  1.00 25.39  ? 180 SER H N   1 
ATOM   2904 C CA  . SER B 2 186 ? -38.621 27.988  -2.069  1.00 35.20  ? 180 SER H CA  1 
ATOM   2905 C C   . SER B 2 186 ? -39.353 29.094  -1.328  1.00 21.16  ? 180 SER H C   1 
ATOM   2906 O O   . SER B 2 186 ? -40.573 29.024  -1.171  1.00 27.28  ? 180 SER H O   1 
ATOM   2907 C CB  . SER B 2 186 ? -38.861 28.105  -3.579  1.00 27.93  ? 180 SER H CB  1 
ATOM   2908 O OG  . SER B 2 186 ? -38.387 29.346  -4.073  1.00 34.61  ? 180 SER H OG  1 
ATOM   2909 N N   . VAL B 2 187 ? -38.613 30.105  -0.868  1.00 20.75  ? 181 VAL H N   1 
ATOM   2910 C CA  . VAL B 2 187 ? -39.178 31.184  -0.068  1.00 34.15  ? 181 VAL H CA  1 
ATOM   2911 C C   . VAL B 2 187 ? -38.749 32.526  -0.649  1.00 33.35  ? 181 VAL H C   1 
ATOM   2912 O O   . VAL B 2 187 ? -37.739 32.634  -1.348  1.00 29.10  ? 181 VAL H O   1 
ATOM   2913 C CB  . VAL B 2 187 ? -38.763 31.087  1.416   1.00 31.16  ? 181 VAL H CB  1 
ATOM   2914 C CG1 . VAL B 2 187 ? -39.325 29.820  2.044   1.00 20.73  ? 181 VAL H CG1 1 
ATOM   2915 C CG2 . VAL B 2 187 ? -37.249 31.126  1.544   1.00 25.24  ? 181 VAL H CG2 1 
ATOM   2916 N N   . VAL B 2 188 ? -39.542 33.557  -0.351  1.00 26.29  ? 182 VAL H N   1 
ATOM   2917 C CA  . VAL B 2 188 ? -39.316 34.907  -0.858  1.00 36.34  ? 182 VAL H CA  1 
ATOM   2918 C C   . VAL B 2 188 ? -39.496 35.906  0.278   1.00 31.48  ? 182 VAL H C   1 
ATOM   2919 O O   . VAL B 2 188 ? -40.342 35.719  1.159   1.00 24.86  ? 182 VAL H O   1 
ATOM   2920 C CB  . VAL B 2 188 ? -40.265 35.252  -2.029  1.00 28.17  ? 182 VAL H CB  1 
ATOM   2921 C CG1 . VAL B 2 188 ? -39.933 36.622  -2.601  1.00 39.96  ? 182 VAL H CG1 1 
ATOM   2922 C CG2 . VAL B 2 188 ? -40.181 34.203  -3.115  1.00 36.57  ? 182 VAL H CG2 1 
ATOM   2923 N N   . THR B 2 189 ? -38.695 36.970  0.254   1.00 27.12  ? 183 THR H N   1 
ATOM   2924 C CA  . THR B 2 189 ? -38.813 38.079  1.193   1.00 37.30  ? 183 THR H CA  1 
ATOM   2925 C C   . THR B 2 189 ? -39.521 39.240  0.501   1.00 46.35  ? 183 THR H C   1 
ATOM   2926 O O   . THR B 2 189 ? -39.023 39.767  -0.500  1.00 46.03  ? 183 THR H O   1 
ATOM   2927 C CB  . THR B 2 189 ? -37.435 38.514  1.691   1.00 42.22  ? 183 THR H CB  1 
ATOM   2928 O OG1 . THR B 2 189 ? -36.727 37.377  2.198   1.00 59.00  ? 183 THR H OG1 1 
ATOM   2929 C CG2 . THR B 2 189 ? -37.570 39.552  2.791   1.00 51.31  ? 183 THR H CG2 1 
ATOM   2930 N N   . VAL B 2 190 ? -40.674 39.636  1.033   1.00 50.64  ? 184 VAL H N   1 
ATOM   2931 C CA  . VAL B 2 190 ? -41.473 40.706  0.436   1.00 49.93  ? 184 VAL H CA  1 
ATOM   2932 C C   . VAL B 2 190 ? -41.879 41.681  1.532   1.00 59.56  ? 184 VAL H C   1 
ATOM   2933 O O   . VAL B 2 190 ? -41.919 41.325  2.721   1.00 46.10  ? 184 VAL H O   1 
ATOM   2934 C CB  . VAL B 2 190 ? -42.719 40.150  -0.296  1.00 45.62  ? 184 VAL H CB  1 
ATOM   2935 C CG1 . VAL B 2 190 ? -42.309 39.207  -1.418  1.00 42.38  ? 184 VAL H CG1 1 
ATOM   2936 C CG2 . VAL B 2 190 ? -43.648 39.456  0.687   1.00 49.49  ? 184 VAL H CG2 1 
ATOM   2937 N N   . PRO B 2 191 ? -42.169 42.932  1.167   1.00 77.03  ? 185 PRO H N   1 
ATOM   2938 C CA  . PRO B 2 191 ? -42.668 43.889  2.162   1.00 65.86  ? 185 PRO H CA  1 
ATOM   2939 C C   . PRO B 2 191 ? -43.978 43.416  2.777   1.00 62.48  ? 185 PRO H C   1 
ATOM   2940 O O   . PRO B 2 191 ? -44.843 42.862  2.097   1.00 61.74  ? 185 PRO H O   1 
ATOM   2941 C CB  . PRO B 2 191 ? -42.859 45.177  1.353   1.00 63.94  ? 185 PRO H CB  1 
ATOM   2942 C CG  . PRO B 2 191 ? -41.932 45.034  0.194   1.00 61.63  ? 185 PRO H CG  1 
ATOM   2943 C CD  . PRO B 2 191 ? -41.924 43.572  -0.139  1.00 63.75  ? 185 PRO H CD  1 
ATOM   2944 N N   . SER B 2 192 ? -44.117 43.651  4.084   1.00 65.14  ? 186 SER H N   1 
ATOM   2945 C CA  . SER B 2 192 ? -45.293 43.185  4.810   1.00 66.36  ? 186 SER H CA  1 
ATOM   2946 C C   . SER B 2 192 ? -46.559 43.937  4.421   1.00 76.29  ? 186 SER H C   1 
ATOM   2947 O O   . SER B 2 192 ? -47.659 43.403  4.595   1.00 82.24  ? 186 SER H O   1 
ATOM   2948 C CB  . SER B 2 192 ? -45.063 43.310  6.316   1.00 65.87  ? 186 SER H CB  1 
ATOM   2949 O OG  . SER B 2 192 ? -46.190 42.854  7.044   1.00 79.55  ? 186 SER H OG  1 
ATOM   2950 N N   . SER B 2 193 ? -46.430 45.157  3.901   1.00 76.13  ? 187 SER H N   1 
ATOM   2951 C CA  . SER B 2 193 ? -47.592 45.966  3.557   1.00 82.41  ? 187 SER H CA  1 
ATOM   2952 C C   . SER B 2 193 ? -48.227 45.570  2.230   1.00 84.36  ? 187 SER H C   1 
ATOM   2953 O O   . SER B 2 193 ? -49.307 46.076  1.907   1.00 85.37  ? 187 SER H O   1 
ATOM   2954 C CB  . SER B 2 193 ? -47.203 47.446  3.517   1.00 77.66  ? 187 SER H CB  1 
ATOM   2955 O OG  . SER B 2 193 ? -46.122 47.662  2.627   1.00 65.68  ? 187 SER H OG  1 
ATOM   2956 N N   . SER B 2 194 ? -47.592 44.689  1.460   1.00 79.17  ? 188 SER H N   1 
ATOM   2957 C CA  . SER B 2 194 ? -48.090 44.297  0.149   1.00 73.52  ? 188 SER H CA  1 
ATOM   2958 C C   . SER B 2 194 ? -48.896 43.005  0.171   1.00 77.09  ? 188 SER H C   1 
ATOM   2959 O O   . SER B 2 194 ? -49.301 42.530  -0.894  1.00 77.31  ? 188 SER H O   1 
ATOM   2960 C CB  . SER B 2 194 ? -46.923 44.153  -0.834  1.00 64.97  ? 188 SER H CB  1 
ATOM   2961 O OG  . SER B 2 194 ? -46.180 45.356  -0.924  1.00 72.22  ? 188 SER H OG  1 
ATOM   2962 N N   . LEU B 2 195 ? -49.135 42.422  1.349   1.00 83.64  ? 189 LEU H N   1 
ATOM   2963 C CA  . LEU B 2 195 ? -49.863 41.158  1.412   1.00 91.11  ? 189 LEU H CA  1 
ATOM   2964 C C   . LEU B 2 195 ? -51.296 41.319  0.920   1.00 93.69  ? 189 LEU H C   1 
ATOM   2965 O O   . LEU B 2 195 ? -51.797 40.494  0.147   1.00 91.45  ? 189 LEU H O   1 
ATOM   2966 C CB  . LEU B 2 195 ? -49.841 40.610  2.840   1.00 89.31  ? 189 LEU H CB  1 
ATOM   2967 C CG  . LEU B 2 195 ? -48.464 40.275  3.419   1.00 84.44  ? 189 LEU H CG  1 
ATOM   2968 C CD1 . LEU B 2 195 ? -48.602 39.575  4.763   1.00 73.82  ? 189 LEU H CD1 1 
ATOM   2969 C CD2 . LEU B 2 195 ? -47.662 39.426  2.444   1.00 66.25  ? 189 LEU H CD2 1 
ATOM   2970 N N   . GLY B 2 196 ? -51.976 42.378  1.364   1.00 98.68  ? 190 GLY H N   1 
ATOM   2971 C CA  . GLY B 2 196 ? -53.342 42.604  0.922   1.00 97.52  ? 190 GLY H CA  1 
ATOM   2972 C C   . GLY B 2 196 ? -53.437 42.980  -0.544  1.00 99.68  ? 190 GLY H C   1 
ATOM   2973 O O   . GLY B 2 196 ? -54.343 42.532  -1.252  1.00 90.50  ? 190 GLY H O   1 
ATOM   2974 N N   . THR B 2 197 ? -52.507 43.809  -1.021  1.00 101.10 ? 191 THR H N   1 
ATOM   2975 C CA  . THR B 2 197 ? -52.575 44.308  -2.391  1.00 92.16  ? 191 THR H CA  1 
ATOM   2976 C C   . THR B 2 197 ? -51.978 43.313  -3.381  1.00 91.44  ? 191 THR H C   1 
ATOM   2977 O O   . THR B 2 197 ? -52.666 42.835  -4.290  1.00 81.50  ? 191 THR H O   1 
ATOM   2978 C CB  . THR B 2 197 ? -51.857 45.657  -2.493  1.00 89.30  ? 191 THR H CB  1 
ATOM   2979 O OG1 . THR B 2 197 ? -50.444 45.460  -2.358  1.00 90.46  ? 191 THR H OG1 1 
ATOM   2980 C CG2 . THR B 2 197 ? -52.335 46.596  -1.395  1.00 90.32  ? 191 THR H CG2 1 
ATOM   2981 N N   . GLN B 2 198 ? -50.697 42.994  -3.221  1.00 93.84  ? 192 GLN H N   1 
ATOM   2982 C CA  . GLN B 2 198 ? -50.011 42.133  -4.173  1.00 82.41  ? 192 GLN H CA  1 
ATOM   2983 C C   . GLN B 2 198 ? -50.433 40.677  -4.010  1.00 75.72  ? 192 GLN H C   1 
ATOM   2984 O O   . GLN B 2 198 ? -50.794 40.224  -2.921  1.00 77.78  ? 192 GLN H O   1 
ATOM   2985 C CB  . GLN B 2 198 ? -48.495 42.251  -4.007  1.00 69.77  ? 192 GLN H CB  1 
ATOM   2986 C CG  . GLN B 2 198 ? -47.849 43.328  -4.863  1.00 70.67  ? 192 GLN H CG  1 
ATOM   2987 C CD  . GLN B 2 198 ? -47.705 42.912  -6.316  1.00 79.76  ? 192 GLN H CD  1 
ATOM   2988 O OE1 . GLN B 2 198 ? -48.059 41.795  -6.694  1.00 74.52  ? 192 GLN H OE1 1 
ATOM   2989 N NE2 . GLN B 2 198 ? -47.178 43.812  -7.138  1.00 68.32  ? 192 GLN H NE2 1 
ATOM   2990 N N   . THR B 2 199 ? -50.383 39.943  -5.120  1.00 62.82  ? 193 THR H N   1 
ATOM   2991 C CA  . THR B 2 199 ? -50.610 38.505  -5.138  1.00 63.61  ? 193 THR H CA  1 
ATOM   2992 C C   . THR B 2 199 ? -49.339 37.819  -5.616  1.00 54.20  ? 193 THR H C   1 
ATOM   2993 O O   . THR B 2 199 ? -48.740 38.237  -6.613  1.00 64.27  ? 193 THR H O   1 
ATOM   2994 C CB  . THR B 2 199 ? -51.798 38.137  -6.037  1.00 61.26  ? 193 THR H CB  1 
ATOM   2995 O OG1 . THR B 2 199 ? -51.835 36.717  -6.230  1.00 55.77  ? 193 THR H OG1 1 
ATOM   2996 C CG2 . THR B 2 199 ? -51.700 38.835  -7.389  1.00 67.10  ? 193 THR H CG2 1 
ATOM   2997 N N   . TYR B 2 200 ? -48.919 36.781  -4.898  1.00 56.25  ? 194 TYR H N   1 
ATOM   2998 C CA  . TYR B 2 200 ? -47.677 36.078  -5.186  1.00 45.84  ? 194 TYR H CA  1 
ATOM   2999 C C   . TYR B 2 200 ? -47.979 34.636  -5.561  1.00 41.59  ? 194 TYR H C   1 
ATOM   3000 O O   . TYR B 2 200 ? -48.667 33.926  -4.819  1.00 41.86  ? 194 TYR H O   1 
ATOM   3001 C CB  . TYR B 2 200 ? -46.724 36.138  -3.990  1.00 39.45  ? 194 TYR H CB  1 
ATOM   3002 C CG  . TYR B 2 200 ? -46.222 37.534  -3.702  1.00 37.23  ? 194 TYR H CG  1 
ATOM   3003 C CD1 . TYR B 2 200 ? -45.180 38.081  -4.440  1.00 39.43  ? 194 TYR H CD1 1 
ATOM   3004 C CD2 . TYR B 2 200 ? -46.794 38.309  -2.702  1.00 38.39  ? 194 TYR H CD2 1 
ATOM   3005 C CE1 . TYR B 2 200 ? -44.718 39.358  -4.187  1.00 35.76  ? 194 TYR H CE1 1 
ATOM   3006 C CE2 . TYR B 2 200 ? -46.337 39.589  -2.441  1.00 39.43  ? 194 TYR H CE2 1 
ATOM   3007 C CZ  . TYR B 2 200 ? -45.299 40.108  -3.187  1.00 44.57  ? 194 TYR H CZ  1 
ATOM   3008 O OH  . TYR B 2 200 ? -44.841 41.380  -2.933  1.00 68.20  ? 194 TYR H OH  1 
ATOM   3009 N N   . ILE B 2 201 ? -47.462 34.211  -6.711  1.00 36.48  ? 195 ILE H N   1 
ATOM   3010 C CA  . ILE B 2 201 ? -47.683 32.873  -7.243  1.00 40.40  ? 195 ILE H CA  1 
ATOM   3011 C C   . ILE B 2 201 ? -46.328 32.232  -7.502  1.00 47.59  ? 195 ILE H C   1 
ATOM   3012 O O   . ILE B 2 201 ? -45.457 32.847  -8.127  1.00 46.75  ? 195 ILE H O   1 
ATOM   3013 C CB  . ILE B 2 201 ? -48.518 32.903  -8.538  1.00 30.64  ? 195 ILE H CB  1 
ATOM   3014 C CG1 . ILE B 2 201 ? -49.898 33.505  -8.272  1.00 39.84  ? 195 ILE H CG1 1 
ATOM   3015 C CG2 . ILE B 2 201 ? -48.643 31.508  -9.132  1.00 28.93  ? 195 ILE H CG2 1 
ATOM   3016 C CD1 . ILE B 2 201 ? -50.766 33.593  -9.504  1.00 32.12  ? 195 ILE H CD1 1 
ATOM   3017 N N   . CYS B 2 202 ? -46.150 31.006  -7.022  1.00 41.37  ? 196 CYS H N   1 
ATOM   3018 C CA  . CYS B 2 202 ? -44.959 30.224  -7.315  1.00 36.26  ? 196 CYS H CA  1 
ATOM   3019 C C   . CYS B 2 202 ? -45.253 29.285  -8.476  1.00 28.41  ? 196 CYS H C   1 
ATOM   3020 O O   . CYS B 2 202 ? -46.328 28.681  -8.546  1.00 38.78  ? 196 CYS H O   1 
ATOM   3021 C CB  . CYS B 2 202 ? -44.496 29.434  -6.088  1.00 43.70  ? 196 CYS H CB  1 
ATOM   3022 S SG  . CYS B 2 202 ? -45.466 27.960  -5.701  1.00 51.21  ? 196 CYS H SG  1 
ATOM   3023 N N   . ASN B 2 203 ? -44.305 29.186  -9.401  1.00 33.28  ? 197 ASN H N   1 
ATOM   3024 C CA  . ASN B 2 203 ? -44.467 28.399  -10.617 1.00 35.83  ? 197 ASN H CA  1 
ATOM   3025 C C   . ASN B 2 203 ? -43.532 27.198  -10.540 1.00 31.79  ? 197 ASN H C   1 
ATOM   3026 O O   . ASN B 2 203 ? -42.307 27.354  -10.580 1.00 26.24  ? 197 ASN H O   1 
ATOM   3027 C CB  . ASN B 2 203 ? -44.180 29.251  -11.851 1.00 31.30  ? 197 ASN H CB  1 
ATOM   3028 C CG  . ASN B 2 203 ? -44.979 30.540  -11.863 1.00 34.09  ? 197 ASN H CG  1 
ATOM   3029 O OD1 . ASN B 2 203 ? -44.441 31.620  -11.622 1.00 39.42  ? 197 ASN H OD1 1 
ATOM   3030 N ND2 . ASN B 2 203 ? -46.273 30.432  -12.142 1.00 40.78  ? 197 ASN H ND2 1 
ATOM   3031 N N   . VAL B 2 204 ? -44.112 26.006  -10.434 1.00 27.65  ? 198 VAL H N   1 
ATOM   3032 C CA  . VAL B 2 204 ? -43.361 24.762  -10.313 1.00 25.41  ? 198 VAL H CA  1 
ATOM   3033 C C   . VAL B 2 204 ? -43.536 23.970  -11.600 1.00 25.58  ? 198 VAL H C   1 
ATOM   3034 O O   . VAL B 2 204 ? -44.666 23.699  -12.022 1.00 34.78  ? 198 VAL H O   1 
ATOM   3035 C CB  . VAL B 2 204 ? -43.818 23.941  -9.095  1.00 26.88  ? 198 VAL H CB  1 
ATOM   3036 C CG1 . VAL B 2 204 ? -43.014 22.653  -8.989  1.00 27.33  ? 198 VAL H CG1 1 
ATOM   3037 C CG2 . VAL B 2 204 ? -43.690 24.765  -7.823  1.00 22.63  ? 198 VAL H CG2 1 
ATOM   3038 N N   . ASN B 2 205 ? -42.418 23.606  -12.223 1.00 26.93  ? 199 ASN H N   1 
ATOM   3039 C CA  . ASN B 2 205 ? -42.419 22.816  -13.446 1.00 42.13  ? 199 ASN H CA  1 
ATOM   3040 C C   . ASN B 2 205 ? -41.517 21.608  -13.254 1.00 36.70  ? 199 ASN H C   1 
ATOM   3041 O O   . ASN B 2 205 ? -40.347 21.755  -12.885 1.00 32.46  ? 199 ASN H O   1 
ATOM   3042 C CB  . ASN B 2 205 ? -41.956 23.653  -14.645 1.00 48.28  ? 199 ASN H CB  1 
ATOM   3043 C CG  . ASN B 2 205 ? -41.741 22.817  -15.893 1.00 51.45  ? 199 ASN H CG  1 
ATOM   3044 O OD1 . ASN B 2 205 ? -42.685 22.264  -16.455 1.00 52.97  ? 199 ASN H OD1 1 
ATOM   3045 N ND2 . ASN B 2 205 ? -40.494 22.732  -16.338 1.00 54.62  ? 199 ASN H ND2 1 
ATOM   3046 N N   . HIS B 2 206 ? -42.061 20.420  -13.502 1.00 36.85  ? 200 HIS H N   1 
ATOM   3047 C CA  . HIS B 2 206 ? -41.335 19.160  -13.371 1.00 36.91  ? 200 HIS H CA  1 
ATOM   3048 C C   . HIS B 2 206 ? -41.389 18.462  -14.727 1.00 42.07  ? 200 HIS H C   1 
ATOM   3049 O O   . HIS B 2 206 ? -42.338 17.734  -15.028 1.00 45.42  ? 200 HIS H O   1 
ATOM   3050 C CB  . HIS B 2 206 ? -41.926 18.296  -12.259 1.00 40.96  ? 200 HIS H CB  1 
ATOM   3051 C CG  . HIS B 2 206 ? -41.137 17.056  -11.974 1.00 31.33  ? 200 HIS H CG  1 
ATOM   3052 N ND1 . HIS B 2 206 ? -41.667 15.791  -12.099 1.00 30.67  ? 200 HIS H ND1 1 
ATOM   3053 C CD2 . HIS B 2 206 ? -39.855 16.888  -11.571 1.00 28.90  ? 200 HIS H CD2 1 
ATOM   3054 C CE1 . HIS B 2 206 ? -40.748 14.896  -11.785 1.00 27.29  ? 200 HIS H CE1 1 
ATOM   3055 N NE2 . HIS B 2 206 ? -39.639 15.536  -11.460 1.00 31.12  ? 200 HIS H NE2 1 
ATOM   3056 N N   . LYS B 2 207 ? -40.362 18.698  -15.541 1.00 41.45  ? 201 LYS H N   1 
ATOM   3057 C CA  . LYS B 2 207 ? -40.339 18.151  -16.896 1.00 45.88  ? 201 LYS H CA  1 
ATOM   3058 C C   . LYS B 2 207 ? -40.416 16.627  -16.960 1.00 47.63  ? 201 LYS H C   1 
ATOM   3059 O O   . LYS B 2 207 ? -41.167 16.120  -17.812 1.00 44.54  ? 201 LYS H O   1 
ATOM   3060 C CB  . LYS B 2 207 ? -39.091 18.662  -17.630 1.00 40.17  ? 201 LYS H CB  1 
ATOM   3061 C CG  . LYS B 2 207 ? -39.023 20.176  -17.742 1.00 43.80  ? 201 LYS H CG  1 
ATOM   3062 C CD  . LYS B 2 207 ? -37.818 20.631  -18.547 1.00 57.68  ? 201 LYS H CD  1 
ATOM   3063 C CE  . LYS B 2 207 ? -37.790 22.147  -18.679 1.00 55.99  ? 201 LYS H CE  1 
ATOM   3064 N NZ  . LYS B 2 207 ? -36.651 22.621  -19.514 1.00 54.50  ? 201 LYS H NZ  1 
ATOM   3065 N N   . PRO B 2 208 ? -39.691 15.850  -16.143 1.00 44.75  ? 202 PRO H N   1 
ATOM   3066 C CA  . PRO B 2 208 ? -39.745 14.386  -16.309 1.00 36.10  ? 202 PRO H CA  1 
ATOM   3067 C C   . PRO B 2 208 ? -41.138 13.794  -16.174 1.00 46.75  ? 202 PRO H C   1 
ATOM   3068 O O   . PRO B 2 208 ? -41.430 12.780  -16.821 1.00 43.44  ? 202 PRO H O   1 
ATOM   3069 C CB  . PRO B 2 208 ? -38.810 13.876  -15.204 1.00 32.49  ? 202 PRO H CB  1 
ATOM   3070 C CG  . PRO B 2 208 ? -37.863 14.992  -14.979 1.00 39.52  ? 202 PRO H CG  1 
ATOM   3071 C CD  . PRO B 2 208 ? -38.683 16.236  -15.137 1.00 40.53  ? 202 PRO H CD  1 
ATOM   3072 N N   . SER B 2 209 ? -42.005 14.382  -15.353 1.00 46.71  ? 203 SER H N   1 
ATOM   3073 C CA  . SER B 2 209 ? -43.368 13.895  -15.195 1.00 40.38  ? 203 SER H CA  1 
ATOM   3074 C C   . SER B 2 209 ? -44.392 14.735  -15.946 1.00 49.25  ? 203 SER H C   1 
ATOM   3075 O O   . SER B 2 209 ? -45.589 14.446  -15.856 1.00 52.19  ? 203 SER H O   1 
ATOM   3076 C CB  . SER B 2 209 ? -43.746 13.840  -13.711 1.00 39.04  ? 203 SER H CB  1 
ATOM   3077 O OG  . SER B 2 209 ? -43.870 15.143  -13.167 1.00 46.25  ? 203 SER H OG  1 
ATOM   3078 N N   . ASN B 2 210 ? -43.953 15.755  -16.683 1.00 50.95  ? 204 ASN H N   1 
ATOM   3079 C CA  . ASN B 2 210 ? -44.839 16.661  -17.412 1.00 51.77  ? 204 ASN H CA  1 
ATOM   3080 C C   . ASN B 2 210 ? -45.879 17.271  -16.470 1.00 54.90  ? 204 ASN H C   1 
ATOM   3081 O O   . ASN B 2 210 ? -47.089 17.087  -16.619 1.00 68.89  ? 204 ASN H O   1 
ATOM   3082 C CB  . ASN B 2 210 ? -45.506 15.945  -18.591 1.00 53.79  ? 204 ASN H CB  1 
ATOM   3083 C CG  . ASN B 2 210 ? -46.296 16.889  -19.477 1.00 69.79  ? 204 ASN H CG  1 
ATOM   3084 O OD1 . ASN B 2 210 ? -46.004 18.084  -19.547 1.00 82.36  ? 204 ASN H OD1 1 
ATOM   3085 N ND2 . ASN B 2 210 ? -47.308 16.359  -20.155 1.00 73.49  ? 204 ASN H ND2 1 
ATOM   3086 N N   . THR B 2 211 ? -45.378 18.001  -15.477 1.00 48.71  ? 205 THR H N   1 
ATOM   3087 C CA  . THR B 2 211 ? -46.219 18.620  -14.463 1.00 42.78  ? 205 THR H CA  1 
ATOM   3088 C C   . THR B 2 211 ? -45.914 20.108  -14.389 1.00 46.38  ? 205 THR H C   1 
ATOM   3089 O O   . THR B 2 211 ? -44.746 20.504  -14.318 1.00 50.87  ? 205 THR H O   1 
ATOM   3090 C CB  . THR B 2 211 ? -46.008 17.971  -13.090 1.00 55.55  ? 205 THR H CB  1 
ATOM   3091 O OG1 . THR B 2 211 ? -46.193 16.554  -13.195 1.00 59.09  ? 205 THR H OG1 1 
ATOM   3092 C CG2 . THR B 2 211 ? -47.002 18.530  -12.081 1.00 47.58  ? 205 THR H CG2 1 
ATOM   3093 N N   . LYS B 2 212 ? -46.965 20.924  -14.411 1.00 49.54  ? 206 LYS H N   1 
ATOM   3094 C CA  . LYS B 2 212 ? -46.857 22.370  -14.260 1.00 38.16  ? 206 LYS H CA  1 
ATOM   3095 C C   . LYS B 2 212 ? -47.933 22.826  -13.290 1.00 37.93  ? 206 LYS H C   1 
ATOM   3096 O O   . LYS B 2 212 ? -49.126 22.702  -13.584 1.00 44.60  ? 206 LYS H O   1 
ATOM   3097 C CB  . LYS B 2 212 ? -47.006 23.082  -15.607 1.00 42.92  ? 206 LYS H CB  1 
ATOM   3098 C CG  . LYS B 2 212 ? -45.705 23.245  -16.371 1.00 53.31  ? 206 LYS H CG  1 
ATOM   3099 C CD  . LYS B 2 212 ? -45.938 23.282  -17.874 1.00 59.71  ? 206 LYS H CD  1 
ATOM   3100 C CE  . LYS B 2 212 ? -47.147 24.134  -18.227 1.00 70.33  ? 206 LYS H CE  1 
ATOM   3101 N NZ  . LYS B 2 212 ? -46.851 25.100  -19.319 1.00 76.96  ? 206 LYS H NZ  1 
ATOM   3102 N N   . VAL B 2 213 ? -47.515 23.347  -12.140 1.00 40.22  ? 207 VAL H N   1 
ATOM   3103 C CA  . VAL B 2 213 ? -48.429 23.770  -11.086 1.00 41.07  ? 207 VAL H CA  1 
ATOM   3104 C C   . VAL B 2 213 ? -48.202 25.249  -10.812 1.00 42.64  ? 207 VAL H C   1 
ATOM   3105 O O   . VAL B 2 213 ? -47.072 25.670  -10.536 1.00 46.81  ? 207 VAL H O   1 
ATOM   3106 C CB  . VAL B 2 213 ? -48.238 22.943  -9.802  1.00 35.71  ? 207 VAL H CB  1 
ATOM   3107 C CG1 . VAL B 2 213 ? -49.252 23.358  -8.748  1.00 32.99  ? 207 VAL H CG1 1 
ATOM   3108 C CG2 . VAL B 2 213 ? -48.353 21.457  -10.106 1.00 37.99  ? 207 VAL H CG2 1 
ATOM   3109 N N   . ASP B 2 214 ? -49.273 26.032  -10.892 1.00 53.17  ? 208 ASP H N   1 
ATOM   3110 C CA  . ASP B 2 214 ? -49.258 27.452  -10.548 1.00 49.91  ? 208 ASP H CA  1 
ATOM   3111 C C   . ASP B 2 214 ? -50.059 27.606  -9.260  1.00 51.18  ? 208 ASP H C   1 
ATOM   3112 O O   . ASP B 2 214 ? -51.291 27.540  -9.273  1.00 63.34  ? 208 ASP H O   1 
ATOM   3113 C CB  . ASP B 2 214 ? -49.838 28.296  -11.680 1.00 50.81  ? 208 ASP H CB  1 
ATOM   3114 C CG  . ASP B 2 214 ? -49.086 28.117  -12.985 1.00 65.49  ? 208 ASP H CG  1 
ATOM   3115 O OD1 . ASP B 2 214 ? -47.837 28.092  -12.957 1.00 61.91  ? 208 ASP H OD1 1 
ATOM   3116 O OD2 . ASP B 2 214 ? -49.745 27.996  -14.040 1.00 72.11  ? 208 ASP H OD2 1 
ATOM   3117 N N   . LYS B 2 215 ? -49.358 27.807  -8.148  1.00 42.99  ? 209 LYS H N   1 
ATOM   3118 C CA  . LYS B 2 215 ? -49.972 27.863  -6.829  1.00 37.43  ? 209 LYS H CA  1 
ATOM   3119 C C   . LYS B 2 215 ? -49.850 29.272  -6.267  1.00 39.56  ? 209 LYS H C   1 
ATOM   3120 O O   . LYS B 2 215 ? -48.757 29.848  -6.254  1.00 43.93  ? 209 LYS H O   1 
ATOM   3121 C CB  . LYS B 2 215 ? -49.322 26.860  -5.875  1.00 41.78  ? 209 LYS H CB  1 
ATOM   3122 C CG  . LYS B 2 215 ? -50.222 26.434  -4.731  1.00 42.24  ? 209 LYS H CG  1 
ATOM   3123 C CD  . LYS B 2 215 ? -51.055 25.222  -5.117  1.00 45.65  ? 209 LYS H CD  1 
ATOM   3124 C CE  . LYS B 2 215 ? -52.350 25.163  -4.323  1.00 55.55  ? 209 LYS H CE  1 
ATOM   3125 N NZ  . LYS B 2 215 ? -53.005 23.830  -4.437  1.00 63.96  ? 209 LYS H NZ  1 
ATOM   3126 N N   . LYS B 2 216 ? -50.968 29.818  -5.800  1.00 41.27  ? 210 LYS H N   1 
ATOM   3127 C CA  . LYS B 2 216 ? -50.992 31.147  -5.212  1.00 41.22  ? 210 LYS H CA  1 
ATOM   3128 C C   . LYS B 2 216 ? -50.770 31.046  -3.709  1.00 41.58  ? 210 LYS H C   1 
ATOM   3129 O O   . LYS B 2 216 ? -51.369 30.196  -3.042  1.00 49.00  ? 210 LYS H O   1 
ATOM   3130 C CB  . LYS B 2 216 ? -52.321 31.842  -5.511  1.00 49.71  ? 210 LYS H CB  1 
ATOM   3131 C CG  . LYS B 2 216 ? -52.857 31.585  -6.911  1.00 57.74  ? 210 LYS H CG  1 
ATOM   3132 C CD  . LYS B 2 216 ? -53.832 32.678  -7.311  1.00 59.07  ? 210 LYS H CD  1 
ATOM   3133 C CE  . LYS B 2 216 ? -55.181 32.117  -7.711  1.00 53.63  ? 210 LYS H CE  1 
ATOM   3134 N NZ  . LYS B 2 216 ? -56.221 33.180  -7.666  1.00 51.45  ? 210 LYS H NZ  1 
ATOM   3135 N N   . VAL B 2 217 ? -49.909 31.909  -3.181  1.00 44.28  ? 211 VAL H N   1 
ATOM   3136 C CA  . VAL B 2 217 ? -49.548 31.907  -1.767  1.00 46.46  ? 211 VAL H CA  1 
ATOM   3137 C C   . VAL B 2 217 ? -50.170 33.150  -1.147  1.00 44.53  ? 211 VAL H C   1 
ATOM   3138 O O   . VAL B 2 217 ? -49.647 34.262  -1.292  1.00 46.11  ? 211 VAL H O   1 
ATOM   3139 C CB  . VAL B 2 217 ? -48.030 31.874  -1.559  1.00 37.97  ? 211 VAL H CB  1 
ATOM   3140 C CG1 . VAL B 2 217 ? -47.699 31.714  -0.080  1.00 41.00  ? 211 VAL H CG1 1 
ATOM   3141 C CG2 . VAL B 2 217 ? -47.411 30.755  -2.375  1.00 33.14  ? 211 VAL H CG2 1 
ATOM   3142 N N   . GLU B 2 218 ? -51.283 32.965  -0.443  1.00 53.07  ? 212 GLU H N   1 
ATOM   3143 C CA  . GLU B 2 218 ? -52.022 34.052  0.172   1.00 61.65  ? 212 GLU H CA  1 
ATOM   3144 C C   . GLU B 2 218 ? -52.039 33.887  1.687   1.00 67.37  ? 212 GLU H C   1 
ATOM   3145 O O   . GLU B 2 218 ? -51.937 32.764  2.191   1.00 68.13  ? 212 GLU H O   1 
ATOM   3146 C CB  . GLU B 2 218 ? -53.461 34.096  -0.359  1.00 62.01  ? 212 GLU H CB  1 
ATOM   3147 C CG  . GLU B 2 218 ? -53.558 33.846  -1.856  1.00 66.76  ? 212 GLU H CG  1 
ATOM   3148 C CD  . GLU B 2 218 ? -54.877 34.300  -2.447  1.00 70.32  ? 212 GLU H CD  1 
ATOM   3149 O OE1 . GLU B 2 218 ? -55.784 34.666  -1.672  1.00 77.50  ? 212 GLU H OE1 1 
ATOM   3150 O OE2 . GLU B 2 218 ? -55.003 34.292  -3.691  1.00 67.10  ? 212 GLU H OE2 1 
ATOM   3151 N N   . PRO B 2 219 ? -52.162 34.989  2.445   1.00 75.26  ? 213 PRO H N   1 
ATOM   3152 C CA  . PRO B 2 219 ? -52.206 34.903  3.911   1.00 62.77  ? 213 PRO H CA  1 
ATOM   3153 C C   . PRO B 2 219 ? -53.447 34.182  4.430   1.00 53.05  ? 213 PRO H C   1 
ATOM   3154 O O   . PRO B 2 219 ? -54.350 33.893  3.644   1.00 54.41  ? 213 PRO H O   1 
ATOM   3155 C CB  . PRO B 2 219 ? -52.209 36.372  4.348   1.00 66.66  ? 213 PRO H CB  1 
ATOM   3156 C CG  . PRO B 2 219 ? -52.745 37.117  3.171   1.00 70.11  ? 213 PRO H CG  1 
ATOM   3157 C CD  . PRO B 2 219 ? -52.221 36.384  1.976   1.00 62.17  ? 213 PRO H CD  1 
ATOM   3158 N N   . GLN C 3 1   ? 22.032  -33.640 -32.479 1.00 60.35  ? 1   GLN F N   1 
ATOM   3159 C CA  . GLN C 3 1   ? 20.920  -34.346 -31.851 1.00 58.37  ? 1   GLN F CA  1 
ATOM   3160 C C   . GLN C 3 1   ? 20.269  -33.492 -30.765 1.00 50.38  ? 1   GLN F C   1 
ATOM   3161 O O   . GLN C 3 1   ? 20.954  -32.858 -29.961 1.00 56.21  ? 1   GLN F O   1 
ATOM   3162 C CB  . GLN C 3 1   ? 21.387  -35.685 -31.268 1.00 54.76  ? 1   GLN F CB  1 
ATOM   3163 C CG  . GLN C 3 1   ? 22.602  -35.598 -30.353 1.00 62.52  ? 1   GLN F CG  1 
ATOM   3164 C CD  . GLN C 3 1   ? 23.914  -35.581 -31.115 1.00 79.87  ? 1   GLN F CD  1 
ATOM   3165 O OE1 . GLN C 3 1   ? 23.953  -35.867 -32.312 1.00 83.59  ? 1   GLN F OE1 1 
ATOM   3166 N NE2 . GLN C 3 1   ? 24.996  -35.241 -30.424 1.00 86.46  ? 1   GLN F NE2 1 
ATOM   3167 N N   . VAL C 3 2   ? 18.939  -33.479 -30.753 1.00 42.65  ? 2   VAL F N   1 
ATOM   3168 C CA  . VAL C 3 2   ? 18.155  -32.685 -29.815 1.00 35.69  ? 2   VAL F CA  1 
ATOM   3169 C C   . VAL C 3 2   ? 17.170  -33.603 -29.107 1.00 37.77  ? 2   VAL F C   1 
ATOM   3170 O O   . VAL C 3 2   ? 16.528  -34.447 -29.742 1.00 38.13  ? 2   VAL F O   1 
ATOM   3171 C CB  . VAL C 3 2   ? 17.410  -31.535 -30.527 1.00 28.29  ? 2   VAL F CB  1 
ATOM   3172 C CG1 . VAL C 3 2   ? 16.503  -30.797 -29.554 1.00 28.74  ? 2   VAL F CG1 1 
ATOM   3173 C CG2 . VAL C 3 2   ? 18.399  -30.577 -31.165 1.00 35.38  ? 2   VAL F CG2 1 
ATOM   3174 N N   . GLN C 3 3   ? 17.058  -33.446 -27.789 1.00 33.68  ? 3   GLN F N   1 
ATOM   3175 C CA  . GLN C 3 3   ? 16.128  -34.231 -26.989 1.00 30.04  ? 3   GLN F CA  1 
ATOM   3176 C C   . GLN C 3 3   ? 15.297  -33.309 -26.110 1.00 26.86  ? 3   GLN F C   1 
ATOM   3177 O O   . GLN C 3 3   ? 15.839  -32.417 -25.450 1.00 31.82  ? 3   GLN F O   1 
ATOM   3178 C CB  . GLN C 3 3   ? 16.864  -35.255 -26.120 1.00 27.05  ? 3   GLN F CB  1 
ATOM   3179 C CG  . GLN C 3 3   ? 17.656  -36.283 -26.900 1.00 28.21  ? 3   GLN F CG  1 
ATOM   3180 C CD  . GLN C 3 3   ? 17.968  -37.510 -26.073 1.00 36.15  ? 3   GLN F CD  1 
ATOM   3181 O OE1 . GLN C 3 3   ? 19.106  -37.977 -26.034 1.00 50.65  ? 3   GLN F OE1 1 
ATOM   3182 N NE2 . GLN C 3 3   ? 16.952  -38.044 -25.407 1.00 30.57  ? 3   GLN F NE2 1 
ATOM   3183 N N   . LEU C 3 4   ? 13.985  -33.531 -26.107 1.00 27.51  ? 4   LEU F N   1 
ATOM   3184 C CA  . LEU C 3 4   ? 13.059  -32.848 -25.211 1.00 23.52  ? 4   LEU F CA  1 
ATOM   3185 C C   . LEU C 3 4   ? 12.214  -33.908 -24.523 1.00 30.15  ? 4   LEU F C   1 
ATOM   3186 O O   . LEU C 3 4   ? 11.494  -34.657 -25.191 1.00 30.70  ? 4   LEU F O   1 
ATOM   3187 C CB  . LEU C 3 4   ? 12.170  -31.861 -25.974 1.00 28.64  ? 4   LEU F CB  1 
ATOM   3188 C CG  . LEU C 3 4   ? 12.865  -30.705 -26.693 1.00 20.63  ? 4   LEU F CG  1 
ATOM   3189 C CD1 . LEU C 3 4   ? 11.905  -30.026 -27.655 1.00 23.12  ? 4   LEU F CD1 1 
ATOM   3190 C CD2 . LEU C 3 4   ? 13.408  -29.705 -25.688 1.00 24.00  ? 4   LEU F CD2 1 
ATOM   3191 N N   . VAL C 3 5   ? 12.308  -33.982 -23.197 1.00 25.89  ? 5   VAL F N   1 
ATOM   3192 C CA  . VAL C 3 5   ? 11.610  -35.001 -22.420 1.00 29.42  ? 5   VAL F CA  1 
ATOM   3193 C C   . VAL C 3 5   ? 10.793  -34.305 -21.341 1.00 28.51  ? 5   VAL F C   1 
ATOM   3194 O O   . VAL C 3 5   ? 11.357  -33.647 -20.459 1.00 29.34  ? 5   VAL F O   1 
ATOM   3195 C CB  . VAL C 3 5   ? 12.581  -36.015 -21.792 1.00 19.78  ? 5   VAL F CB  1 
ATOM   3196 C CG1 . VAL C 3 5   ? 11.810  -37.137 -21.116 1.00 23.10  ? 5   VAL F CG1 1 
ATOM   3197 C CG2 . VAL C 3 5   ? 13.527  -36.573 -22.847 1.00 24.82  ? 5   VAL F CG2 1 
ATOM   3198 N N   . GLU C 3 6   ? 9.473   -34.458 -21.406 1.00 25.46  ? 6   GLU F N   1 
ATOM   3199 C CA  . GLU C 3 6   ? 8.573   -33.881 -20.420 1.00 22.17  ? 6   GLU F CA  1 
ATOM   3200 C C   . GLU C 3 6   ? 8.339   -34.853 -19.268 1.00 23.23  ? 6   GLU F C   1 
ATOM   3201 O O   . GLU C 3 6   ? 8.475   -36.071 -19.409 1.00 24.61  ? 6   GLU F O   1 
ATOM   3202 C CB  . GLU C 3 6   ? 7.231   -33.508 -21.053 1.00 35.93  ? 6   GLU F CB  1 
ATOM   3203 C CG  . GLU C 3 6   ? 7.316   -32.498 -22.179 1.00 35.86  ? 6   GLU F CG  1 
ATOM   3204 C CD  . GLU C 3 6   ? 7.499   -33.146 -23.538 1.00 32.48  ? 6   GLU F CD  1 
ATOM   3205 O OE1 . GLU C 3 6   ? 7.971   -34.301 -23.593 1.00 33.56  ? 6   GLU F OE1 1 
ATOM   3206 O OE2 . GLU C 3 6   ? 7.159   -32.502 -24.551 1.00 27.44  ? 6   GLU F OE2 1 
ATOM   3207 N N   . SER C 3 7   ? 7.978   -34.292 -18.117 1.00 18.57  ? 7   SER F N   1 
ATOM   3208 C CA  . SER C 3 7   ? 7.635   -35.090 -16.950 1.00 26.53  ? 7   SER F CA  1 
ATOM   3209 C C   . SER C 3 7   ? 6.765   -34.252 -16.025 1.00 28.40  ? 7   SER F C   1 
ATOM   3210 O O   . SER C 3 7   ? 6.690   -33.027 -16.155 1.00 23.25  ? 7   SER F O   1 
ATOM   3211 C CB  . SER C 3 7   ? 8.886   -35.589 -16.218 1.00 25.94  ? 7   SER F CB  1 
ATOM   3212 O OG  . SER C 3 7   ? 9.709   -34.507 -15.818 1.00 27.94  ? 7   SER F OG  1 
ATOM   3213 N N   . GLY C 3 8   ? 6.109   -34.931 -15.087 1.00 25.20  ? 8   GLY F N   1 
ATOM   3214 C CA  . GLY C 3 8   ? 5.259   -34.279 -14.113 1.00 27.44  ? 8   GLY F CA  1 
ATOM   3215 C C   . GLY C 3 8   ? 3.772   -34.378 -14.375 1.00 27.56  ? 8   GLY F C   1 
ATOM   3216 O O   . GLY C 3 8   ? 2.989   -33.820 -13.597 1.00 22.87  ? 8   GLY F O   1 
ATOM   3217 N N   . GLY C 3 9   ? 3.356   -35.062 -15.440 1.00 30.58  ? 9   GLY F N   1 
ATOM   3218 C CA  . GLY C 3 9   ? 1.944   -35.224 -15.701 1.00 35.75  ? 9   GLY F CA  1 
ATOM   3219 C C   . GLY C 3 9   ? 1.308   -36.305 -14.846 1.00 44.28  ? 9   GLY F C   1 
ATOM   3220 O O   . GLY C 3 9   ? 1.968   -37.214 -14.342 1.00 50.40  ? 9   GLY F O   1 
ATOM   3221 N N   . GLY C 3 10  ? -0.005  -36.196 -14.685 1.00 34.75  ? 10  GLY F N   1 
ATOM   3222 C CA  . GLY C 3 10  ? -0.742  -37.168 -13.906 1.00 30.01  ? 10  GLY F CA  1 
ATOM   3223 C C   . GLY C 3 10  ? -2.120  -36.642 -13.558 1.00 30.30  ? 10  GLY F C   1 
ATOM   3224 O O   . GLY C 3 10  ? -2.528  -35.567 -14.004 1.00 26.94  ? 10  GLY F O   1 
ATOM   3225 N N   . LEU C 3 11  ? -2.830  -37.429 -12.754 1.00 37.62  ? 11  LEU F N   1 
ATOM   3226 C CA  . LEU C 3 11  ? -4.149  -37.025 -12.291 1.00 27.81  ? 11  LEU F CA  1 
ATOM   3227 C C   . LEU C 3 11  ? -4.031  -35.919 -11.249 1.00 29.56  ? 11  LEU F C   1 
ATOM   3228 O O   . LEU C 3 11  ? -3.133  -35.931 -10.403 1.00 35.55  ? 11  LEU F O   1 
ATOM   3229 C CB  . LEU C 3 11  ? -4.897  -38.223 -11.705 1.00 32.59  ? 11  LEU F CB  1 
ATOM   3230 C CG  . LEU C 3 11  ? -6.265  -37.940 -11.081 1.00 31.18  ? 11  LEU F CG  1 
ATOM   3231 C CD1 . LEU C 3 11  ? -7.239  -37.412 -12.125 1.00 29.08  ? 11  LEU F CD1 1 
ATOM   3232 C CD2 . LEU C 3 11  ? -6.818  -39.183 -10.404 1.00 37.88  ? 11  LEU F CD2 1 
ATOM   3233 N N   . ILE C 3 12  ? -4.944  -34.955 -11.318 1.00 32.52  ? 12  ILE F N   1 
ATOM   3234 C CA  . ILE C 3 12  ? -4.986  -33.854 -10.363 1.00 28.60  ? 12  ILE F CA  1 
ATOM   3235 C C   . ILE C 3 12  ? -6.429  -33.386 -10.243 1.00 37.26  ? 12  ILE F C   1 
ATOM   3236 O O   . ILE C 3 12  ? -7.152  -33.299 -11.240 1.00 40.04  ? 12  ILE F O   1 
ATOM   3237 C CB  . ILE C 3 12  ? -4.040  -32.708 -10.789 1.00 40.28  ? 12  ILE F CB  1 
ATOM   3238 C CG1 . ILE C 3 12  ? -4.140  -31.526 -9.821  1.00 38.57  ? 12  ILE F CG1 1 
ATOM   3239 C CG2 . ILE C 3 12  ? -4.325  -32.278 -12.222 1.00 40.48  ? 12  ILE F CG2 1 
ATOM   3240 C CD1 . ILE C 3 12  ? -3.669  -31.845 -8.419  1.00 38.01  ? 12  ILE F CD1 1 
ATOM   3241 N N   . GLN C 3 13  ? -6.855  -33.103 -9.015  1.00 42.26  ? 13  GLN F N   1 
ATOM   3242 C CA  . GLN C 3 13  ? -8.218  -32.652 -8.796  1.00 43.61  ? 13  GLN F CA  1 
ATOM   3243 C C   . GLN C 3 13  ? -8.394  -31.229 -9.325  1.00 45.36  ? 13  GLN F C   1 
ATOM   3244 O O   . GLN C 3 13  ? -7.424  -30.474 -9.432  1.00 42.16  ? 13  GLN F O   1 
ATOM   3245 C CB  . GLN C 3 13  ? -8.576  -32.706 -7.310  1.00 45.83  ? 13  GLN F CB  1 
ATOM   3246 C CG  . GLN C 3 13  ? -7.959  -31.603 -6.461  1.00 41.94  ? 13  GLN F CG  1 
ATOM   3247 C CD  . GLN C 3 13  ? -6.517  -31.882 -6.084  1.00 58.35  ? 13  GLN F CD  1 
ATOM   3248 O OE1 . GLN C 3 13  ? -6.000  -32.973 -6.322  1.00 50.47  ? 13  GLN F OE1 1 
ATOM   3249 N NE2 . GLN C 3 13  ? -5.861  -30.893 -5.486  1.00 51.17  ? 13  GLN F NE2 1 
ATOM   3250 N N   . PRO C 3 14  ? -9.620  -30.848 -9.688  1.00 42.72  ? 14  PRO F N   1 
ATOM   3251 C CA  . PRO C 3 14  ? -9.856  -29.469 -10.132 1.00 29.48  ? 14  PRO F CA  1 
ATOM   3252 C C   . PRO C 3 14  ? -9.485  -28.467 -9.050  1.00 31.10  ? 14  PRO F C   1 
ATOM   3253 O O   . PRO C 3 14  ? -9.697  -28.700 -7.858  1.00 47.44  ? 14  PRO F O   1 
ATOM   3254 C CB  . PRO C 3 14  ? -11.359 -29.446 -10.430 1.00 28.82  ? 14  PRO F CB  1 
ATOM   3255 C CG  . PRO C 3 14  ? -11.694 -30.863 -10.750 1.00 38.33  ? 14  PRO F CG  1 
ATOM   3256 C CD  . PRO C 3 14  ? -10.809 -31.698 -9.868  1.00 44.01  ? 14  PRO F CD  1 
ATOM   3257 N N   . GLY C 3 15  ? -8.918  -27.342 -9.480  1.00 38.72  ? 15  GLY F N   1 
ATOM   3258 C CA  . GLY C 3 15  ? -8.465  -26.314 -8.569  1.00 27.40  ? 15  GLY F CA  1 
ATOM   3259 C C   . GLY C 3 15  ? -7.108  -26.561 -7.949  1.00 31.97  ? 15  GLY F C   1 
ATOM   3260 O O   . GLY C 3 15  ? -6.626  -25.705 -7.196  1.00 37.32  ? 15  GLY F O   1 
ATOM   3261 N N   . GLY C 3 16  ? -6.473  -27.695 -8.241  1.00 36.39  ? 16  GLY F N   1 
ATOM   3262 C CA  . GLY C 3 16  ? -5.184  -28.025 -7.677  1.00 42.01  ? 16  GLY F CA  1 
ATOM   3263 C C   . GLY C 3 16  ? -4.036  -27.431 -8.470  1.00 47.68  ? 16  GLY F C   1 
ATOM   3264 O O   . GLY C 3 16  ? -4.217  -26.653 -9.408  1.00 41.47  ? 16  GLY F O   1 
ATOM   3265 N N   . SER C 3 17  ? -2.827  -27.819 -8.076  1.00 44.79  ? 17  SER F N   1 
ATOM   3266 C CA  . SER C 3 17  ? -1.606  -27.343 -8.706  1.00 32.30  ? 17  SER F CA  1 
ATOM   3267 C C   . SER C 3 17  ? -0.807  -28.513 -9.263  1.00 38.21  ? 17  SER F C   1 
ATOM   3268 O O   . SER C 3 17  ? -0.784  -29.605 -8.688  1.00 44.86  ? 17  SER F O   1 
ATOM   3269 C CB  . SER C 3 17  ? -0.740  -26.546 -7.722  1.00 42.09  ? 17  SER F CB  1 
ATOM   3270 O OG  . SER C 3 17  ? -1.297  -25.268 -7.469  1.00 53.42  ? 17  SER F OG  1 
ATOM   3271 N N   . LEU C 3 18  ? -0.155  -28.269 -10.397 1.00 33.20  ? 18  LEU F N   1 
ATOM   3272 C CA  . LEU C 3 18  ? 0.708   -29.257 -11.025 1.00 30.30  ? 18  LEU F CA  1 
ATOM   3273 C C   . LEU C 3 18  ? 1.849   -28.521 -11.711 1.00 38.14  ? 18  LEU F C   1 
ATOM   3274 O O   . LEU C 3 18  ? 1.636   -27.474 -12.327 1.00 42.18  ? 18  LEU F O   1 
ATOM   3275 C CB  . LEU C 3 18  ? -0.066  -30.117 -12.031 1.00 26.38  ? 18  LEU F CB  1 
ATOM   3276 C CG  . LEU C 3 18  ? 0.605   -31.411 -12.495 1.00 39.14  ? 18  LEU F CG  1 
ATOM   3277 C CD1 . LEU C 3 18  ? 0.846   -32.338 -11.314 1.00 26.44  ? 18  LEU F CD1 1 
ATOM   3278 C CD2 . LEU C 3 18  ? -0.238  -32.101 -13.557 1.00 37.89  ? 18  LEU F CD2 1 
ATOM   3279 N N   . ARG C 3 19  ? 3.057   -29.066 -11.594 1.00 28.53  ? 19  ARG F N   1 
ATOM   3280 C CA  . ARG C 3 19  ? 4.257   -28.447 -12.142 1.00 20.93  ? 19  ARG F CA  1 
ATOM   3281 C C   . ARG C 3 19  ? 4.887   -29.397 -13.149 1.00 25.77  ? 19  ARG F C   1 
ATOM   3282 O O   . ARG C 3 19  ? 5.222   -30.536 -12.806 1.00 19.85  ? 19  ARG F O   1 
ATOM   3283 C CB  . ARG C 3 19  ? 5.248   -28.098 -11.029 1.00 29.04  ? 19  ARG F CB  1 
ATOM   3284 C CG  . ARG C 3 19  ? 6.542   -27.458 -11.508 1.00 29.01  ? 19  ARG F CG  1 
ATOM   3285 C CD  . ARG C 3 19  ? 7.443   -27.136 -10.328 1.00 24.65  ? 19  ARG F CD  1 
ATOM   3286 N NE  . ARG C 3 19  ? 8.731   -26.588 -10.736 1.00 40.26  ? 19  ARG F NE  1 
ATOM   3287 C CZ  . ARG C 3 19  ? 9.000   -25.293 -10.826 1.00 45.81  ? 19  ARG F CZ  1 
ATOM   3288 N NH1 . ARG C 3 19  ? 8.085   -24.376 -10.556 1.00 39.70  ? 19  ARG F NH1 1 
ATOM   3289 N NH2 . ARG C 3 19  ? 10.219  -24.907 -11.193 1.00 39.67  ? 19  ARG F NH2 1 
ATOM   3290 N N   . LEU C 3 20  ? 5.053   -28.926 -14.381 1.00 22.03  ? 20  LEU F N   1 
ATOM   3291 C CA  . LEU C 3 20  ? 5.636   -29.721 -15.450 1.00 21.61  ? 20  LEU F CA  1 
ATOM   3292 C C   . LEU C 3 20  ? 7.097   -29.346 -15.653 1.00 20.51  ? 20  LEU F C   1 
ATOM   3293 O O   . LEU C 3 20  ? 7.489   -28.186 -15.503 1.00 21.46  ? 20  LEU F O   1 
ATOM   3294 C CB  . LEU C 3 20  ? 4.868   -29.530 -16.758 1.00 22.10  ? 20  LEU F CB  1 
ATOM   3295 C CG  . LEU C 3 20  ? 3.388   -29.913 -16.742 1.00 25.74  ? 20  LEU F CG  1 
ATOM   3296 C CD1 . LEU C 3 20  ? 2.789   -29.775 -18.132 1.00 21.46  ? 20  LEU F CD1 1 
ATOM   3297 C CD2 . LEU C 3 20  ? 3.201   -31.326 -16.209 1.00 23.34  ? 20  LEU F CD2 1 
ATOM   3298 N N   . SER C 3 21  ? 7.902   -30.347 -15.996 1.00 20.82  ? 21  SER F N   1 
ATOM   3299 C CA  . SER C 3 21  ? 9.323   -30.163 -16.247 1.00 21.42  ? 21  SER F CA  1 
ATOM   3300 C C   . SER C 3 21  ? 9.668   -30.698 -17.627 1.00 21.82  ? 21  SER F C   1 
ATOM   3301 O O   . SER C 3 21  ? 9.095   -31.688 -18.090 1.00 28.48  ? 21  SER F O   1 
ATOM   3302 C CB  . SER C 3 21  ? 10.179  -30.867 -15.185 1.00 23.02  ? 21  SER F CB  1 
ATOM   3303 O OG  . SER C 3 21  ? 9.914   -30.352 -13.892 1.00 30.91  ? 21  SER F OG  1 
ATOM   3304 N N   . CYS C 3 22  ? 10.615  -30.030 -18.281 1.00 25.87  ? 22  CYS F N   1 
ATOM   3305 C CA  . CYS C 3 22  ? 11.073  -30.417 -19.614 1.00 23.73  ? 22  CYS F CA  1 
ATOM   3306 C C   . CYS C 3 22  ? 12.591  -30.336 -19.647 1.00 23.76  ? 22  CYS F C   1 
ATOM   3307 O O   . CYS C 3 22  ? 13.153  -29.239 -19.717 1.00 22.18  ? 22  CYS F O   1 
ATOM   3308 C CB  . CYS C 3 22  ? 10.460  -29.522 -20.692 1.00 25.46  ? 22  CYS F CB  1 
ATOM   3309 S SG  . CYS C 3 22  ? 11.213  -29.715 -22.327 1.00 48.66  ? 22  CYS F SG  1 
ATOM   3310 N N   . ALA C 3 23  ? 13.252  -31.488 -19.594 1.00 20.32  ? 23  ALA F N   1 
ATOM   3311 C CA  . ALA C 3 23  ? 14.699  -31.531 -19.741 1.00 26.95  ? 23  ALA F CA  1 
ATOM   3312 C C   . ALA C 3 23  ? 15.073  -31.420 -21.213 1.00 21.93  ? 23  ALA F C   1 
ATOM   3313 O O   . ALA C 3 23  ? 14.455  -32.050 -22.075 1.00 27.89  ? 23  ALA F O   1 
ATOM   3314 C CB  . ALA C 3 23  ? 15.263  -32.822 -19.147 1.00 19.65  ? 23  ALA F CB  1 
ATOM   3315 N N   . ALA C 3 24  ? 16.090  -30.611 -21.499 1.00 28.21  ? 24  ALA F N   1 
ATOM   3316 C CA  . ALA C 3 24  ? 16.498  -30.345 -22.870 1.00 31.34  ? 24  ALA F CA  1 
ATOM   3317 C C   . ALA C 3 24  ? 17.992  -30.573 -23.030 1.00 28.17  ? 24  ALA F C   1 
ATOM   3318 O O   . ALA C 3 24  ? 18.786  -30.196 -22.162 1.00 30.50  ? 24  ALA F O   1 
ATOM   3319 C CB  . ALA C 3 24  ? 16.143  -28.914 -23.287 1.00 27.39  ? 24  ALA F CB  1 
ATOM   3320 N N   . SER C 3 25  ? 18.366  -31.194 -24.147 1.00 25.64  ? 25  SER F N   1 
ATOM   3321 C CA  . SER C 3 25  ? 19.760  -31.385 -24.512 1.00 26.56  ? 25  SER F CA  1 
ATOM   3322 C C   . SER C 3 25  ? 19.917  -31.109 -26.000 1.00 39.95  ? 25  SER F C   1 
ATOM   3323 O O   . SER C 3 25  ? 18.963  -31.231 -26.774 1.00 30.59  ? 25  SER F O   1 
ATOM   3324 C CB  . SER C 3 25  ? 20.249  -32.802 -24.178 1.00 35.71  ? 25  SER F CB  1 
ATOM   3325 O OG  . SER C 3 25  ? 19.575  -33.772 -24.960 1.00 40.25  ? 25  SER F OG  1 
ATOM   3326 N N   . GLY C 3 26  ? 21.132  -30.734 -26.394 1.00 27.11  ? 26  GLY F N   1 
ATOM   3327 C CA  . GLY C 3 26  ? 21.428  -30.413 -27.774 1.00 28.85  ? 26  GLY F CA  1 
ATOM   3328 C C   . GLY C 3 26  ? 21.347  -28.945 -28.128 1.00 31.30  ? 26  GLY F C   1 
ATOM   3329 O O   . GLY C 3 26  ? 21.646  -28.586 -29.273 1.00 35.30  ? 26  GLY F O   1 
ATOM   3330 N N   . PHE C 3 27  ? 20.948  -28.089 -27.190 1.00 21.20  ? 27  PHE F N   1 
ATOM   3331 C CA  . PHE C 3 27  ? 20.920  -26.650 -27.410 1.00 24.41  ? 27  PHE F CA  1 
ATOM   3332 C C   . PHE C 3 27  ? 20.907  -25.963 -26.052 1.00 21.61  ? 27  PHE F C   1 
ATOM   3333 O O   . PHE C 3 27  ? 20.656  -26.590 -25.020 1.00 34.89  ? 27  PHE F O   1 
ATOM   3334 C CB  . PHE C 3 27  ? 19.716  -26.229 -28.263 1.00 27.35  ? 27  PHE F CB  1 
ATOM   3335 C CG  . PHE C 3 27  ? 18.386  -26.495 -27.616 1.00 21.96  ? 27  PHE F CG  1 
ATOM   3336 C CD1 . PHE C 3 27  ? 17.800  -27.747 -27.698 1.00 25.35  ? 27  PHE F CD1 1 
ATOM   3337 C CD2 . PHE C 3 27  ? 17.716  -25.490 -26.936 1.00 26.89  ? 27  PHE F CD2 1 
ATOM   3338 C CE1 . PHE C 3 27  ? 16.577  -27.995 -27.106 1.00 25.27  ? 27  PHE F CE1 1 
ATOM   3339 C CE2 . PHE C 3 27  ? 16.491  -25.732 -26.343 1.00 22.89  ? 27  PHE F CE2 1 
ATOM   3340 C CZ  . PHE C 3 27  ? 15.921  -26.986 -26.429 1.00 18.31  ? 27  PHE F CZ  1 
ATOM   3341 N N   . THR C 3 28  ? 21.186  -24.662 -26.064 1.00 22.31  ? 28  THR F N   1 
ATOM   3342 C CA  . THR C 3 28  ? 21.237  -23.866 -24.841 1.00 27.77  ? 28  THR F CA  1 
ATOM   3343 C C   . THR C 3 28  ? 19.839  -23.332 -24.547 1.00 28.04  ? 28  THR F C   1 
ATOM   3344 O O   . THR C 3 28  ? 19.295  -22.536 -25.319 1.00 31.73  ? 28  THR F O   1 
ATOM   3345 C CB  . THR C 3 28  ? 22.246  -22.729 -24.975 1.00 31.23  ? 28  THR F CB  1 
ATOM   3346 O OG1 . THR C 3 28  ? 23.526  -23.265 -25.337 1.00 34.07  ? 28  THR F OG1 1 
ATOM   3347 C CG2 . THR C 3 28  ? 22.376  -21.977 -23.658 1.00 23.42  ? 28  THR F CG2 1 
ATOM   3348 N N   . VAL C 3 29  ? 19.259  -23.774 -23.427 1.00 30.45  ? 29  VAL F N   1 
ATOM   3349 C CA  . VAL C 3 29  ? 17.897  -23.378 -23.077 1.00 28.21  ? 29  VAL F CA  1 
ATOM   3350 C C   . VAL C 3 29  ? 17.806  -21.871 -22.880 1.00 28.14  ? 29  VAL F C   1 
ATOM   3351 O O   . VAL C 3 29  ? 16.873  -21.221 -23.369 1.00 31.88  ? 29  VAL F O   1 
ATOM   3352 C CB  . VAL C 3 29  ? 17.429  -24.142 -21.824 1.00 32.14  ? 29  VAL F CB  1 
ATOM   3353 C CG1 . VAL C 3 29  ? 16.174  -23.506 -21.245 1.00 33.56  ? 29  VAL F CG1 1 
ATOM   3354 C CG2 . VAL C 3 29  ? 17.180  -25.601 -22.158 1.00 24.21  ? 29  VAL F CG2 1 
ATOM   3355 N N   . SER C 3 30  ? 18.772  -21.289 -22.170 1.00 34.21  ? 30  SER F N   1 
ATOM   3356 C CA  . SER C 3 30  ? 18.744  -19.863 -21.871 1.00 30.53  ? 30  SER F CA  1 
ATOM   3357 C C   . SER C 3 30  ? 18.927  -18.987 -23.105 1.00 26.05  ? 30  SER F C   1 
ATOM   3358 O O   . SER C 3 30  ? 18.693  -17.777 -23.020 1.00 26.29  ? 30  SER F O   1 
ATOM   3359 C CB  . SER C 3 30  ? 19.820  -19.527 -20.837 1.00 32.81  ? 30  SER F CB  1 
ATOM   3360 O OG  . SER C 3 30  ? 21.108  -19.892 -21.302 1.00 33.43  ? 30  SER F OG  1 
ATOM   3361 N N   . SER C 3 31  ? 19.339  -19.555 -24.238 1.00 26.99  ? 31  SER F N   1 
ATOM   3362 C CA  . SER C 3 31  ? 19.582  -18.787 -25.450 1.00 26.49  ? 31  SER F CA  1 
ATOM   3363 C C   . SER C 3 31  ? 18.496  -18.951 -26.505 1.00 22.67  ? 31  SER F C   1 
ATOM   3364 O O   . SER C 3 31  ? 18.645  -18.419 -27.610 1.00 19.77  ? 31  SER F O   1 
ATOM   3365 C CB  . SER C 3 31  ? 20.938  -19.173 -26.057 1.00 28.67  ? 31  SER F CB  1 
ATOM   3366 O OG  . SER C 3 31  ? 21.999  -18.908 -25.157 1.00 29.05  ? 31  SER F OG  1 
ATOM   3367 N N   . ASN C 3 32  ? 17.410  -19.660 -26.203 1.00 19.16  ? 32  ASN F N   1 
ATOM   3368 C CA  . ASN C 3 32  ? 16.401  -19.985 -27.200 1.00 24.21  ? 32  ASN F CA  1 
ATOM   3369 C C   . ASN C 3 32  ? 15.005  -19.660 -26.691 1.00 24.89  ? 32  ASN F C   1 
ATOM   3370 O O   . ASN C 3 32  ? 14.747  -19.654 -25.484 1.00 21.69  ? 32  ASN F O   1 
ATOM   3371 C CB  . ASN C 3 32  ? 16.458  -21.469 -27.591 1.00 28.22  ? 32  ASN F CB  1 
ATOM   3372 C CG  . ASN C 3 32  ? 17.616  -21.787 -28.512 1.00 29.94  ? 32  ASN F CG  1 
ATOM   3373 O OD1 . ASN C 3 32  ? 17.436  -21.949 -29.720 1.00 30.81  ? 32  ASN F OD1 1 
ATOM   3374 N ND2 . ASN C 3 32  ? 18.814  -21.880 -27.948 1.00 20.16  ? 32  ASN F ND2 1 
ATOM   3375 N N   . TYR C 3 33  ? 14.108  -19.380 -27.634 1.00 21.75  ? 33  TYR F N   1 
ATOM   3376 C CA  . TYR C 3 33  ? 12.685  -19.330 -27.329 1.00 25.03  ? 33  TYR F CA  1 
ATOM   3377 C C   . TYR C 3 33  ? 12.176  -20.738 -27.047 1.00 20.88  ? 33  TYR F C   1 
ATOM   3378 O O   . TYR C 3 33  ? 12.525  -21.692 -27.748 1.00 23.47  ? 33  TYR F O   1 
ATOM   3379 C CB  . TYR C 3 33  ? 11.898  -18.731 -28.497 1.00 21.30  ? 33  TYR F CB  1 
ATOM   3380 C CG  . TYR C 3 33  ? 12.205  -17.291 -28.851 1.00 25.84  ? 33  TYR F CG  1 
ATOM   3381 C CD1 . TYR C 3 33  ? 13.429  -16.929 -29.401 1.00 23.33  ? 33  TYR F CD1 1 
ATOM   3382 C CD2 . TYR C 3 33  ? 11.249  -16.300 -28.678 1.00 22.13  ? 33  TYR F CD2 1 
ATOM   3383 C CE1 . TYR C 3 33  ? 13.700  -15.615 -29.739 1.00 25.15  ? 33  TYR F CE1 1 
ATOM   3384 C CE2 . TYR C 3 33  ? 11.510  -14.986 -29.018 1.00 22.12  ? 33  TYR F CE2 1 
ATOM   3385 C CZ  . TYR C 3 33  ? 12.736  -14.648 -29.546 1.00 23.14  ? 33  TYR F CZ  1 
ATOM   3386 O OH  . TYR C 3 33  ? 12.996  -13.340 -29.883 1.00 27.37  ? 33  TYR F OH  1 
ATOM   3387 N N   . MET C 3 34  ? 11.346  -20.873 -26.015 1.00 18.66  ? 34  MET F N   1 
ATOM   3388 C CA  . MET C 3 34  ? 10.739  -22.152 -25.674 1.00 24.46  ? 34  MET F CA  1 
ATOM   3389 C C   . MET C 3 34  ? 9.257   -21.955 -25.404 1.00 21.02  ? 34  MET F C   1 
ATOM   3390 O O   . MET C 3 34  ? 8.850   -20.931 -24.848 1.00 19.83  ? 34  MET F O   1 
ATOM   3391 C CB  . MET C 3 34  ? 11.416  -22.792 -24.457 1.00 26.14  ? 34  MET F CB  1 
ATOM   3392 C CG  . MET C 3 34  ? 12.913  -22.987 -24.618 1.00 22.92  ? 34  MET F CG  1 
ATOM   3393 S SD  . MET C 3 34  ? 13.457  -24.663 -24.243 1.00 42.67  ? 34  MET F SD  1 
ATOM   3394 C CE  . MET C 3 34  ? 12.755  -25.565 -25.620 1.00 36.03  ? 34  MET F CE  1 
ATOM   3395 N N   . SER C 3 35  ? 8.453   -22.942 -25.794 1.00 19.19  ? 35  SER F N   1 
ATOM   3396 C CA  . SER C 3 35  ? 7.007   -22.850 -25.669 1.00 24.85  ? 35  SER F CA  1 
ATOM   3397 C C   . SER C 3 35  ? 6.439   -24.151 -25.124 1.00 24.96  ? 35  SER F C   1 
ATOM   3398 O O   . SER C 3 35  ? 7.035   -25.223 -25.255 1.00 15.33  ? 35  SER F O   1 
ATOM   3399 C CB  . SER C 3 35  ? 6.335   -22.529 -27.012 1.00 19.83  ? 35  SER F CB  1 
ATOM   3400 O OG  . SER C 3 35  ? 6.556   -21.184 -27.394 1.00 25.22  ? 35  SER F OG  1 
ATOM   3401 N N   . TRP C 3 36  ? 5.270   -24.032 -24.502 1.00 24.35  ? 36  TRP F N   1 
ATOM   3402 C CA  . TRP C 3 36  ? 4.424   -25.166 -24.162 1.00 21.52  ? 36  TRP F CA  1 
ATOM   3403 C C   . TRP C 3 36  ? 3.207   -25.152 -25.075 1.00 18.87  ? 36  TRP F C   1 
ATOM   3404 O O   . TRP C 3 36  ? 2.540   -24.121 -25.212 1.00 15.14  ? 36  TRP F O   1 
ATOM   3405 C CB  . TRP C 3 36  ? 3.985   -25.117 -22.696 1.00 24.53  ? 36  TRP F CB  1 
ATOM   3406 C CG  . TRP C 3 36  ? 5.080   -25.413 -21.720 1.00 25.57  ? 36  TRP F CG  1 
ATOM   3407 C CD1 . TRP C 3 36  ? 5.887   -24.508 -21.095 1.00 22.54  ? 36  TRP F CD1 1 
ATOM   3408 C CD2 . TRP C 3 36  ? 5.486   -26.705 -21.251 1.00 18.74  ? 36  TRP F CD2 1 
ATOM   3409 N NE1 . TRP C 3 36  ? 6.772   -25.156 -20.268 1.00 23.42  ? 36  TRP F NE1 1 
ATOM   3410 C CE2 . TRP C 3 36  ? 6.547   -26.505 -20.346 1.00 22.05  ? 36  TRP F CE2 1 
ATOM   3411 C CE3 . TRP C 3 36  ? 5.057   -28.010 -21.510 1.00 19.01  ? 36  TRP F CE3 1 
ATOM   3412 C CZ2 . TRP C 3 36  ? 7.184   -27.561 -19.697 1.00 21.31  ? 36  TRP F CZ2 1 
ATOM   3413 C CZ3 . TRP C 3 36  ? 5.692   -29.058 -20.866 1.00 18.07  ? 36  TRP F CZ3 1 
ATOM   3414 C CH2 . TRP C 3 36  ? 6.743   -28.826 -19.970 1.00 23.10  ? 36  TRP F CH2 1 
ATOM   3415 N N   . VAL C 3 37  ? 2.932   -26.288 -25.709 1.00 15.77  ? 37  VAL F N   1 
ATOM   3416 C CA  . VAL C 3 37  ? 1.773   -26.453 -26.579 1.00 26.56  ? 37  VAL F CA  1 
ATOM   3417 C C   . VAL C 3 37  ? 1.003   -27.677 -26.107 1.00 23.68  ? 37  VAL F C   1 
ATOM   3418 O O   . VAL C 3 37  ? 1.588   -28.751 -25.934 1.00 25.06  ? 37  VAL F O   1 
ATOM   3419 C CB  . VAL C 3 37  ? 2.181   -26.601 -28.057 1.00 24.99  ? 37  VAL F CB  1 
ATOM   3420 C CG1 . VAL C 3 37  ? 0.954   -26.817 -28.929 1.00 19.67  ? 37  VAL F CG1 1 
ATOM   3421 C CG2 . VAL C 3 37  ? 2.962   -25.378 -28.517 1.00 21.66  ? 37  VAL F CG2 1 
ATOM   3422 N N   . ARG C 3 38  ? -0.300  -27.519 -25.900 1.00 19.39  ? 38  ARG F N   1 
ATOM   3423 C CA  . ARG C 3 38  ? -1.130  -28.593 -25.378 1.00 27.72  ? 38  ARG F CA  1 
ATOM   3424 C C   . ARG C 3 38  ? -2.151  -29.035 -26.417 1.00 28.38  ? 38  ARG F C   1 
ATOM   3425 O O   . ARG C 3 38  ? -2.583  -28.251 -27.268 1.00 25.34  ? 38  ARG F O   1 
ATOM   3426 C CB  . ARG C 3 38  ? -1.843  -28.173 -24.089 1.00 19.66  ? 38  ARG F CB  1 
ATOM   3427 C CG  . ARG C 3 38  ? -2.979  -27.187 -24.279 1.00 19.71  ? 38  ARG F CG  1 
ATOM   3428 C CD  . ARG C 3 38  ? -3.576  -26.803 -22.936 1.00 28.91  ? 38  ARG F CD  1 
ATOM   3429 N NE  . ARG C 3 38  ? -4.642  -25.817 -23.060 1.00 23.70  ? 38  ARG F NE  1 
ATOM   3430 C CZ  . ARG C 3 38  ? -5.252  -25.244 -22.032 1.00 28.23  ? 38  ARG F CZ  1 
ATOM   3431 N NH1 . ARG C 3 38  ? -4.921  -25.533 -20.784 1.00 34.97  ? 38  ARG F NH1 1 
ATOM   3432 N NH2 . ARG C 3 38  ? -6.216  -24.357 -22.261 1.00 34.20  ? 38  ARG F NH2 1 
ATOM   3433 N N   . GLN C 3 39  ? -2.523  -30.310 -26.340 1.00 28.16  ? 39  GLN F N   1 
ATOM   3434 C CA  . GLN C 3 39  ? -3.458  -30.925 -27.276 1.00 27.41  ? 39  GLN F CA  1 
ATOM   3435 C C   . GLN C 3 39  ? -4.482  -31.718 -26.476 1.00 25.55  ? 39  GLN F C   1 
ATOM   3436 O O   . GLN C 3 39  ? -4.139  -32.731 -25.857 1.00 21.55  ? 39  GLN F O   1 
ATOM   3437 C CB  . GLN C 3 39  ? -2.724  -31.824 -28.271 1.00 22.16  ? 39  GLN F CB  1 
ATOM   3438 C CG  . GLN C 3 39  ? -3.617  -32.440 -29.330 1.00 23.25  ? 39  GLN F CG  1 
ATOM   3439 C CD  . GLN C 3 39  ? -2.852  -33.317 -30.301 1.00 30.86  ? 39  GLN F CD  1 
ATOM   3440 O OE1 . GLN C 3 39  ? -1.983  -34.093 -29.904 1.00 27.09  ? 39  GLN F OE1 1 
ATOM   3441 N NE2 . GLN C 3 39  ? -3.168  -33.192 -31.584 1.00 32.36  ? 39  GLN F NE2 1 
ATOM   3442 N N   . ALA C 3 40  ? -5.730  -31.257 -26.485 1.00 35.40  ? 40  ALA F N   1 
ATOM   3443 C CA  . ALA C 3 40  ? -6.793  -31.971 -25.797 1.00 33.82  ? 40  ALA F CA  1 
ATOM   3444 C C   . ALA C 3 40  ? -6.999  -33.340 -26.444 1.00 37.88  ? 40  ALA F C   1 
ATOM   3445 O O   . ALA C 3 40  ? -6.728  -33.516 -27.636 1.00 37.92  ? 40  ALA F O   1 
ATOM   3446 C CB  . ALA C 3 40  ? -8.089  -31.163 -25.834 1.00 36.09  ? 40  ALA F CB  1 
ATOM   3447 N N   . PRO C 3 41  ? -7.455  -34.333 -25.678 1.00 49.96  ? 41  PRO F N   1 
ATOM   3448 C CA  . PRO C 3 41  ? -7.581  -35.696 -26.222 1.00 46.29  ? 41  PRO F CA  1 
ATOM   3449 C C   . PRO C 3 41  ? -8.469  -35.736 -27.456 1.00 48.53  ? 41  PRO F C   1 
ATOM   3450 O O   . PRO C 3 41  ? -9.664  -35.437 -27.397 1.00 37.92  ? 41  PRO F O   1 
ATOM   3451 C CB  . PRO C 3 41  ? -8.194  -36.482 -25.057 1.00 44.06  ? 41  PRO F CB  1 
ATOM   3452 C CG  . PRO C 3 41  ? -7.792  -35.724 -23.841 1.00 36.96  ? 41  PRO F CG  1 
ATOM   3453 C CD  . PRO C 3 41  ? -7.797  -34.280 -24.245 1.00 37.76  ? 41  PRO F CD  1 
ATOM   3454 N N   . GLY C 3 42  ? -7.867  -36.105 -28.586 1.00 44.42  ? 42  GLY F N   1 
ATOM   3455 C CA  . GLY C 3 42  ? -8.580  -36.238 -29.837 1.00 52.13  ? 42  GLY F CA  1 
ATOM   3456 C C   . GLY C 3 42  ? -8.814  -34.950 -30.596 1.00 53.27  ? 42  GLY F C   1 
ATOM   3457 O O   . GLY C 3 42  ? -9.459  -34.986 -31.652 1.00 51.53  ? 42  GLY F O   1 
ATOM   3458 N N   . LYS C 3 43  ? -8.311  -33.821 -30.108 1.00 54.57  ? 43  LYS F N   1 
ATOM   3459 C CA  . LYS C 3 43  ? -8.545  -32.522 -30.726 1.00 49.44  ? 43  LYS F CA  1 
ATOM   3460 C C   . LYS C 3 43  ? -7.211  -31.935 -31.197 1.00 42.42  ? 43  LYS F C   1 
ATOM   3461 O O   . LYS C 3 43  ? -6.178  -32.611 -31.204 1.00 41.97  ? 43  LYS F O   1 
ATOM   3462 C CB  . LYS C 3 43  ? -9.276  -31.585 -29.758 1.00 44.37  ? 43  LYS F CB  1 
ATOM   3463 C CG  . LYS C 3 43  ? -10.449 -32.224 -29.009 1.00 50.96  ? 43  LYS F CG  1 
ATOM   3464 C CD  . LYS C 3 43  ? -11.382 -33.016 -29.930 1.00 60.26  ? 43  LYS F CD  1 
ATOM   3465 C CE  . LYS C 3 43  ? -12.282 -32.128 -30.774 1.00 60.76  ? 43  LYS F CE  1 
ATOM   3466 N NZ  . LYS C 3 43  ? -13.475 -31.660 -30.013 1.00 51.87  ? 43  LYS F NZ  1 
ATOM   3467 N N   . GLY C 3 44  ? -7.247  -30.672 -31.613 1.00 36.33  ? 44  GLY F N   1 
ATOM   3468 C CA  . GLY C 3 44  ? -6.102  -30.025 -32.217 1.00 39.83  ? 44  GLY F CA  1 
ATOM   3469 C C   . GLY C 3 44  ? -5.127  -29.450 -31.205 1.00 41.15  ? 44  GLY F C   1 
ATOM   3470 O O   . GLY C 3 44  ? -5.217  -29.670 -29.997 1.00 42.30  ? 44  GLY F O   1 
ATOM   3471 N N   . LEU C 3 45  ? -4.172  -28.685 -31.732 1.00 34.41  ? 45  LEU F N   1 
ATOM   3472 C CA  . LEU C 3 45  ? -3.096  -28.116 -30.935 1.00 25.46  ? 45  LEU F CA  1 
ATOM   3473 C C   . LEU C 3 45  ? -3.436  -26.695 -30.505 1.00 24.05  ? 45  LEU F C   1 
ATOM   3474 O O   . LEU C 3 45  ? -4.050  -25.933 -31.257 1.00 25.14  ? 45  LEU F O   1 
ATOM   3475 C CB  . LEU C 3 45  ? -1.787  -28.120 -31.726 1.00 21.47  ? 45  LEU F CB  1 
ATOM   3476 C CG  . LEU C 3 45  ? -1.268  -29.477 -32.200 1.00 29.45  ? 45  LEU F CG  1 
ATOM   3477 C CD1 . LEU C 3 45  ? -0.162  -29.291 -33.226 1.00 30.85  ? 45  LEU F CD1 1 
ATOM   3478 C CD2 . LEU C 3 45  ? -0.772  -30.307 -31.026 1.00 28.66  ? 45  LEU F CD2 1 
ATOM   3479 N N   . GLU C 3 46  ? -3.035  -26.345 -29.285 1.00 21.96  ? 46  GLU F N   1 
ATOM   3480 C CA  . GLU C 3 46  ? -3.242  -25.003 -28.760 1.00 23.69  ? 46  GLU F CA  1 
ATOM   3481 C C   . GLU C 3 46  ? -1.963  -24.519 -28.095 1.00 25.60  ? 46  GLU F C   1 
ATOM   3482 O O   . GLU C 3 46  ? -1.400  -25.218 -27.247 1.00 31.49  ? 46  GLU F O   1 
ATOM   3483 C CB  . GLU C 3 46  ? -4.402  -24.975 -27.757 1.00 22.67  ? 46  GLU F CB  1 
ATOM   3484 C CG  . GLU C 3 46  ? -4.617  -23.625 -27.088 1.00 27.87  ? 46  GLU F CG  1 
ATOM   3485 C CD  . GLU C 3 46  ? -5.653  -23.682 -25.980 1.00 33.98  ? 46  GLU F CD  1 
ATOM   3486 O OE1 . GLU C 3 46  ? -6.190  -24.780 -25.723 1.00 34.00  ? 46  GLU F OE1 1 
ATOM   3487 O OE2 . GLU C 3 46  ? -5.930  -22.629 -25.366 1.00 44.55  ? 46  GLU F OE2 1 
ATOM   3488 N N   . TRP C 3 47  ? -1.514  -23.324 -28.466 1.00 22.77  ? 47  TRP F N   1 
ATOM   3489 C CA  . TRP C 3 47  ? -0.361  -22.720 -27.813 1.00 25.53  ? 47  TRP F CA  1 
ATOM   3490 C C   . TRP C 3 47  ? -0.734  -22.186 -26.434 1.00 26.59  ? 47  TRP F C   1 
ATOM   3491 O O   . TRP C 3 47  ? -1.757  -21.510 -26.265 1.00 30.82  ? 47  TRP F O   1 
ATOM   3492 C CB  . TRP C 3 47  ? 0.212   -21.594 -28.675 1.00 15.74  ? 47  TRP F CB  1 
ATOM   3493 C CG  . TRP C 3 47  ? 1.238   -20.761 -27.962 1.00 19.25  ? 47  TRP F CG  1 
ATOM   3494 C CD1 . TRP C 3 47  ? 2.567   -21.043 -27.810 1.00 17.92  ? 47  TRP F CD1 1 
ATOM   3495 C CD2 . TRP C 3 47  ? 1.017   -19.509 -27.303 1.00 16.18  ? 47  TRP F CD2 1 
ATOM   3496 N NE1 . TRP C 3 47  ? 3.184   -20.043 -27.096 1.00 19.63  ? 47  TRP F NE1 1 
ATOM   3497 C CE2 . TRP C 3 47  ? 2.254   -19.090 -26.773 1.00 15.70  ? 47  TRP F CE2 1 
ATOM   3498 C CE3 . TRP C 3 47  ? -0.108  -18.702 -27.108 1.00 17.91  ? 47  TRP F CE3 1 
ATOM   3499 C CZ2 . TRP C 3 47  ? 2.397   -17.898 -26.064 1.00 19.74  ? 47  TRP F CZ2 1 
ATOM   3500 C CZ3 . TRP C 3 47  ? 0.035   -17.520 -26.403 1.00 16.57  ? 47  TRP F CZ3 1 
ATOM   3501 C CH2 . TRP C 3 47  ? 1.278   -17.130 -25.890 1.00 24.77  ? 47  TRP F CH2 1 
ATOM   3502 N N   . VAL C 3 48  ? 0.119   -22.471 -25.449 1.00 20.53  ? 48  VAL F N   1 
ATOM   3503 C CA  . VAL C 3 48  ? -0.135  -22.122 -24.050 1.00 19.98  ? 48  VAL F CA  1 
ATOM   3504 C C   . VAL C 3 48  ? 0.720   -20.926 -23.615 1.00 22.09  ? 48  VAL F C   1 
ATOM   3505 O O   . VAL C 3 48  ? 0.194   -19.892 -23.204 1.00 21.66  ? 48  VAL F O   1 
ATOM   3506 C CB  . VAL C 3 48  ? 0.096   -23.337 -23.121 1.00 19.46  ? 48  VAL F CB  1 
ATOM   3507 C CG1 . VAL C 3 48  ? -0.254  -23.007 -21.676 1.00 21.17  ? 48  VAL F CG1 1 
ATOM   3508 C CG2 . VAL C 3 48  ? -0.691  -24.536 -23.599 1.00 20.54  ? 48  VAL F CG2 1 
ATOM   3509 N N   . SER C 3 49  ? 2.046   -21.056 -23.689 1.00 20.78  ? 49  SER F N   1 
ATOM   3510 C CA  . SER C 3 49  ? 2.927   -19.994 -23.226 1.00 22.12  ? 49  SER F CA  1 
ATOM   3511 C C   . SER C 3 49  ? 4.261   -20.070 -23.954 1.00 20.08  ? 49  SER F C   1 
ATOM   3512 O O   . SER C 3 49  ? 4.612   -21.089 -24.547 1.00 22.84  ? 49  SER F O   1 
ATOM   3513 C CB  . SER C 3 49  ? 3.141   -20.067 -21.713 1.00 18.55  ? 49  SER F CB  1 
ATOM   3514 O OG  . SER C 3 49  ? 3.732   -21.303 -21.346 1.00 28.12  ? 49  SER F OG  1 
ATOM   3515 N N   . VAL C 3 50  ? 5.009   -18.969 -23.890 1.00 24.30  ? 50  VAL F N   1 
ATOM   3516 C CA  . VAL C 3 50  ? 6.337   -18.892 -24.490 1.00 18.57  ? 50  VAL F CA  1 
ATOM   3517 C C   . VAL C 3 50  ? 7.245   -18.123 -23.544 1.00 20.89  ? 50  VAL F C   1 
ATOM   3518 O O   . VAL C 3 50  ? 6.796   -17.248 -22.798 1.00 21.80  ? 50  VAL F O   1 
ATOM   3519 C CB  . VAL C 3 50  ? 6.300   -18.229 -25.888 1.00 22.43  ? 50  VAL F CB  1 
ATOM   3520 C CG1 . VAL C 3 50  ? 5.864   -16.779 -25.778 1.00 14.15  ? 50  VAL F CG1 1 
ATOM   3521 C CG2 . VAL C 3 50  ? 7.660   -18.330 -26.587 1.00 18.90  ? 50  VAL F CG2 1 
ATOM   3522 N N   . ILE C 3 51  ? 8.527   -18.471 -23.555 1.00 23.06  ? 51  ILE F N   1 
ATOM   3523 C CA  . ILE C 3 51  ? 9.555   -17.680 -22.893 1.00 20.64  ? 51  ILE F CA  1 
ATOM   3524 C C   . ILE C 3 51  ? 10.579  -17.279 -23.945 1.00 19.13  ? 51  ILE F C   1 
ATOM   3525 O O   . ILE C 3 51  ? 11.061  -18.125 -24.707 1.00 21.42  ? 51  ILE F O   1 
ATOM   3526 C CB  . ILE C 3 51  ? 10.209  -18.437 -21.721 1.00 17.25  ? 51  ILE F CB  1 
ATOM   3527 C CG1 . ILE C 3 51  ? 11.321  -17.590 -21.096 1.00 25.95  ? 51  ILE F CG1 1 
ATOM   3528 C CG2 . ILE C 3 51  ? 10.723  -19.802 -22.162 1.00 17.82  ? 51  ILE F CG2 1 
ATOM   3529 C CD1 . ILE C 3 51  ? 11.776  -18.085 -19.746 1.00 21.39  ? 51  ILE F CD1 1 
ATOM   3530 N N   . TYR C 3 52  ? 10.876  -15.986 -24.013 1.00 22.32  ? 52  TYR F N   1 
ATOM   3531 C CA  . TYR C 3 52  ? 11.817  -15.490 -25.003 1.00 19.43  ? 52  TYR F CA  1 
ATOM   3532 C C   . TYR C 3 52  ? 13.249  -15.806 -24.583 1.00 24.67  ? 52  TYR F C   1 
ATOM   3533 O O   . TYR C 3 52  ? 13.529  -16.135 -23.426 1.00 28.93  ? 52  TYR F O   1 
ATOM   3534 C CB  . TYR C 3 52  ? 11.647  -13.984 -25.208 1.00 18.72  ? 52  TYR F CB  1 
ATOM   3535 C CG  . TYR C 3 52  ? 10.472  -13.598 -26.083 1.00 24.83  ? 52  TYR F CG  1 
ATOM   3536 C CD1 . TYR C 3 52  ? 9.479   -14.517 -26.401 1.00 24.73  ? 52  TYR F CD1 1 
ATOM   3537 C CD2 . TYR C 3 52  ? 10.364  -12.315 -26.605 1.00 24.08  ? 52  TYR F CD2 1 
ATOM   3538 C CE1 . TYR C 3 52  ? 8.411   -14.167 -27.206 1.00 27.68  ? 52  TYR F CE1 1 
ATOM   3539 C CE2 . TYR C 3 52  ? 9.298   -11.956 -27.410 1.00 20.48  ? 52  TYR F CE2 1 
ATOM   3540 C CZ  . TYR C 3 52  ? 8.325   -12.886 -27.707 1.00 21.64  ? 52  TYR F CZ  1 
ATOM   3541 O OH  . TYR C 3 52  ? 7.262   -12.536 -28.508 1.00 30.75  ? 52  TYR F OH  1 
ATOM   3542 N N   . SER C 3 53  ? 14.164  -15.703 -25.551 1.00 20.16  ? 53  SER F N   1 
ATOM   3543 C CA  . SER C 3 53  ? 15.573  -15.957 -25.266 1.00 23.41  ? 53  SER F CA  1 
ATOM   3544 C C   . SER C 3 53  ? 16.113  -14.996 -24.216 1.00 27.66  ? 53  SER F C   1 
ATOM   3545 O O   . SER C 3 53  ? 17.035  -15.345 -23.470 1.00 27.62  ? 53  SER F O   1 
ATOM   3546 C CB  . SER C 3 53  ? 16.396  -15.863 -26.552 1.00 26.55  ? 53  SER F CB  1 
ATOM   3547 O OG  . SER C 3 53  ? 16.301  -14.572 -27.129 1.00 34.34  ? 53  SER F OG  1 
ATOM   3548 N N   . GLY C 3 54  ? 15.553  -13.791 -24.140 1.00 24.84  ? 54  GLY F N   1 
ATOM   3549 C CA  . GLY C 3 54  ? 15.904  -12.814 -23.133 1.00 18.55  ? 54  GLY F CA  1 
ATOM   3550 C C   . GLY C 3 54  ? 15.142  -12.921 -21.834 1.00 17.69  ? 54  GLY F C   1 
ATOM   3551 O O   . GLY C 3 54  ? 15.338  -12.088 -20.943 1.00 17.38  ? 54  GLY F O   1 
ATOM   3552 N N   . GLY C 3 55  ? 14.267  -13.918 -21.694 1.00 22.90  ? 55  GLY F N   1 
ATOM   3553 C CA  . GLY C 3 55  ? 13.551  -14.158 -20.459 1.00 23.91  ? 55  GLY F CA  1 
ATOM   3554 C C   . GLY C 3 55  ? 12.121  -13.658 -20.430 1.00 27.92  ? 55  GLY F C   1 
ATOM   3555 O O   . GLY C 3 55  ? 11.396  -13.970 -19.477 1.00 31.02  ? 55  GLY F O   1 
ATOM   3556 N N   . SER C 3 56  ? 11.696  -12.894 -21.431 1.00 27.02  ? 56  SER F N   1 
ATOM   3557 C CA  . SER C 3 56  ? 10.330  -12.390 -21.459 1.00 27.77  ? 56  SER F CA  1 
ATOM   3558 C C   . SER C 3 56  ? 9.340   -13.524 -21.693 1.00 20.76  ? 56  SER F C   1 
ATOM   3559 O O   . SER C 3 56  ? 9.604   -14.451 -22.464 1.00 19.54  ? 56  SER F O   1 
ATOM   3560 C CB  . SER C 3 56  ? 10.181  -11.327 -22.543 1.00 23.92  ? 56  SER F CB  1 
ATOM   3561 O OG  . SER C 3 56  ? 10.815  -10.121 -22.153 1.00 28.64  ? 56  SER F OG  1 
ATOM   3562 N N   . THR C 3 57  ? 8.190   -13.441 -21.029 1.00 19.07  ? 57  THR F N   1 
ATOM   3563 C CA  . THR C 3 57  ? 7.201   -14.508 -21.031 1.00 27.43  ? 57  THR F CA  1 
ATOM   3564 C C   . THR C 3 57  ? 5.850   -13.989 -21.506 1.00 24.13  ? 57  THR F C   1 
ATOM   3565 O O   . THR C 3 57  ? 5.480   -12.840 -21.246 1.00 25.25  ? 57  THR F O   1 
ATOM   3566 C CB  . THR C 3 57  ? 7.045   -15.124 -19.635 1.00 24.35  ? 57  THR F CB  1 
ATOM   3567 O OG1 . THR C 3 57  ? 6.564   -14.128 -18.723 1.00 26.10  ? 57  THR F OG1 1 
ATOM   3568 C CG2 . THR C 3 57  ? 8.379   -15.658 -19.134 1.00 18.91  ? 57  THR F CG2 1 
ATOM   3569 N N   . PHE C 3 58  ? 5.115   -14.852 -22.205 1.00 21.57  ? 58  PHE F N   1 
ATOM   3570 C CA  . PHE C 3 58  ? 3.773   -14.541 -22.674 1.00 23.24  ? 58  PHE F CA  1 
ATOM   3571 C C   . PHE C 3 58  ? 2.898   -15.777 -22.535 1.00 26.03  ? 58  PHE F C   1 
ATOM   3572 O O   . PHE C 3 58  ? 3.391   -16.908 -22.559 1.00 20.13  ? 58  PHE F O   1 
ATOM   3573 C CB  . PHE C 3 58  ? 3.782   -14.054 -24.127 1.00 26.63  ? 58  PHE F CB  1 
ATOM   3574 C CG  . PHE C 3 58  ? 4.540   -12.778 -24.326 1.00 26.24  ? 58  PHE F CG  1 
ATOM   3575 C CD1 . PHE C 3 58  ? 3.929   -11.555 -24.109 1.00 16.54  ? 58  PHE F CD1 1 
ATOM   3576 C CD2 . PHE C 3 58  ? 5.868   -12.799 -24.720 1.00 22.76  ? 58  PHE F CD2 1 
ATOM   3577 C CE1 . PHE C 3 58  ? 4.624   -10.378 -24.286 1.00 23.52  ? 58  PHE F CE1 1 
ATOM   3578 C CE2 . PHE C 3 58  ? 6.569   -11.625 -24.899 1.00 20.37  ? 58  PHE F CE2 1 
ATOM   3579 C CZ  . PHE C 3 58  ? 5.945   -10.413 -24.684 1.00 30.28  ? 58  PHE F CZ  1 
ATOM   3580 N N   . TYR C 3 59  ? 1.593   -15.551 -22.391 1.00 24.83  ? 59  TYR F N   1 
ATOM   3581 C CA  . TYR C 3 59  ? 0.651   -16.626 -22.115 1.00 28.05  ? 59  TYR F CA  1 
ATOM   3582 C C   . TYR C 3 59  ? -0.595  -16.466 -22.972 1.00 26.06  ? 59  TYR F C   1 
ATOM   3583 O O   . TYR C 3 59  ? -0.959  -15.356 -23.368 1.00 28.07  ? 59  TYR F O   1 
ATOM   3584 C CB  . TYR C 3 59  ? 0.248   -16.654 -20.634 1.00 22.32  ? 59  TYR F CB  1 
ATOM   3585 C CG  . TYR C 3 59  ? 1.411   -16.770 -19.679 1.00 23.72  ? 59  TYR F CG  1 
ATOM   3586 C CD1 . TYR C 3 59  ? 1.868   -18.012 -19.261 1.00 20.43  ? 59  TYR F CD1 1 
ATOM   3587 C CD2 . TYR C 3 59  ? 2.051   -15.638 -19.191 1.00 24.73  ? 59  TYR F CD2 1 
ATOM   3588 C CE1 . TYR C 3 59  ? 2.932   -18.125 -18.389 1.00 26.38  ? 59  TYR F CE1 1 
ATOM   3589 C CE2 . TYR C 3 59  ? 3.115   -15.740 -18.316 1.00 23.55  ? 59  TYR F CE2 1 
ATOM   3590 C CZ  . TYR C 3 59  ? 3.551   -16.987 -17.919 1.00 25.77  ? 59  TYR F CZ  1 
ATOM   3591 O OH  . TYR C 3 59  ? 4.611   -17.097 -17.049 1.00 28.84  ? 59  TYR F OH  1 
ATOM   3592 N N   . ALA C 3 60  ? -1.247  -17.592 -23.249 1.00 19.68  ? 60  ALA F N   1 
ATOM   3593 C CA  . ALA C 3 60  ? -2.560  -17.560 -23.871 1.00 21.75  ? 60  ALA F CA  1 
ATOM   3594 C C   . ALA C 3 60  ? -3.583  -16.981 -22.901 1.00 31.79  ? 60  ALA F C   1 
ATOM   3595 O O   . ALA C 3 60  ? -3.427  -17.058 -21.680 1.00 37.26  ? 60  ALA F O   1 
ATOM   3596 C CB  . ALA C 3 60  ? -2.981  -18.962 -24.310 1.00 20.55  ? 60  ALA F CB  1 
ATOM   3597 N N   . ASP C 3 61  ? -4.640  -16.387 -23.461 1.00 39.25  ? 61  ASP F N   1 
ATOM   3598 C CA  . ASP C 3 61  ? -5.655  -15.750 -22.627 1.00 39.14  ? 61  ASP F CA  1 
ATOM   3599 C C   . ASP C 3 61  ? -6.362  -16.754 -21.725 1.00 34.98  ? 61  ASP F C   1 
ATOM   3600 O O   . ASP C 3 61  ? -6.760  -16.408 -20.606 1.00 33.05  ? 61  ASP F O   1 
ATOM   3601 C CB  . ASP C 3 61  ? -6.671  -15.020 -23.504 1.00 46.26  ? 61  ASP F CB  1 
ATOM   3602 C CG  . ASP C 3 61  ? -6.157  -13.685 -24.000 1.00 61.86  ? 61  ASP F CG  1 
ATOM   3603 O OD1 . ASP C 3 61  ? -5.653  -12.899 -23.170 1.00 55.07  ? 61  ASP F OD1 1 
ATOM   3604 O OD2 . ASP C 3 61  ? -6.249  -13.424 -25.219 1.00 58.68  ? 61  ASP F OD2 1 
ATOM   3605 N N   . SER C 3 62  ? -6.526  -17.995 -22.186 1.00 32.29  ? 62  SER F N   1 
ATOM   3606 C CA  . SER C 3 62  ? -7.256  -18.989 -21.408 1.00 42.35  ? 62  SER F CA  1 
ATOM   3607 C C   . SER C 3 62  ? -6.487  -19.461 -20.179 1.00 48.80  ? 62  SER F C   1 
ATOM   3608 O O   . SER C 3 62  ? -7.097  -20.032 -19.269 1.00 40.80  ? 62  SER F O   1 
ATOM   3609 C CB  . SER C 3 62  ? -7.606  -20.189 -22.290 1.00 37.58  ? 62  SER F CB  1 
ATOM   3610 O OG  . SER C 3 62  ? -6.437  -20.807 -22.800 1.00 41.22  ? 62  SER F OG  1 
ATOM   3611 N N   . VAL C 3 63  ? -5.174  -19.239 -20.126 1.00 32.28  ? 63  VAL F N   1 
ATOM   3612 C CA  . VAL C 3 63  ? -4.343  -19.720 -19.030 1.00 27.13  ? 63  VAL F CA  1 
ATOM   3613 C C   . VAL C 3 63  ? -3.648  -18.597 -18.278 1.00 33.33  ? 63  VAL F C   1 
ATOM   3614 O O   . VAL C 3 63  ? -2.950  -18.867 -17.296 1.00 31.34  ? 63  VAL F O   1 
ATOM   3615 C CB  . VAL C 3 63  ? -3.302  -20.746 -19.522 1.00 32.44  ? 63  VAL F CB  1 
ATOM   3616 C CG1 . VAL C 3 63  ? -3.981  -21.878 -20.280 1.00 33.44  ? 63  VAL F CG1 1 
ATOM   3617 C CG2 . VAL C 3 63  ? -2.252  -20.065 -20.386 1.00 32.73  ? 63  VAL F CG2 1 
ATOM   3618 N N   . LYS C 3 64  ? -3.808  -17.348 -18.707 1.00 33.17  ? 64  LYS F N   1 
ATOM   3619 C CA  . LYS C 3 64  ? -3.113  -16.245 -18.060 1.00 30.72  ? 64  LYS F CA  1 
ATOM   3620 C C   . LYS C 3 64  ? -3.638  -16.033 -16.645 1.00 37.22  ? 64  LYS F C   1 
ATOM   3621 O O   . LYS C 3 64  ? -4.840  -16.138 -16.386 1.00 48.62  ? 64  LYS F O   1 
ATOM   3622 C CB  . LYS C 3 64  ? -3.267  -14.968 -18.882 1.00 32.63  ? 64  LYS F CB  1 
ATOM   3623 C CG  . LYS C 3 64  ? -2.366  -13.832 -18.436 1.00 43.96  ? 64  LYS F CG  1 
ATOM   3624 C CD  . LYS C 3 64  ? -1.938  -12.996 -19.628 1.00 52.34  ? 64  LYS F CD  1 
ATOM   3625 C CE  . LYS C 3 64  ? -1.360  -11.665 -19.194 1.00 48.26  ? 64  LYS F CE  1 
ATOM   3626 N NZ  . LYS C 3 64  ? -1.727  -10.596 -20.163 1.00 60.03  ? 64  LYS F NZ  1 
ATOM   3627 N N   . GLY C 3 65  ? -2.722  -15.735 -15.724 1.00 39.00  ? 65  GLY F N   1 
ATOM   3628 C CA  . GLY C 3 65  ? -3.056  -15.611 -14.323 1.00 42.89  ? 65  GLY F CA  1 
ATOM   3629 C C   . GLY C 3 65  ? -3.086  -16.915 -13.560 1.00 42.45  ? 65  GLY F C   1 
ATOM   3630 O O   . GLY C 3 65  ? -3.163  -16.889 -12.324 1.00 38.46  ? 65  GLY F O   1 
ATOM   3631 N N   . ARG C 3 66  ? -3.025  -18.053 -14.248 1.00 32.78  ? 66  ARG F N   1 
ATOM   3632 C CA  . ARG C 3 66  ? -2.998  -19.363 -13.615 1.00 29.56  ? 66  ARG F CA  1 
ATOM   3633 C C   . ARG C 3 66  ? -1.738  -20.157 -13.918 1.00 28.49  ? 66  ARG F C   1 
ATOM   3634 O O   . ARG C 3 66  ? -1.291  -20.924 -13.061 1.00 30.30  ? 66  ARG F O   1 
ATOM   3635 C CB  . ARG C 3 66  ? -4.222  -20.190 -14.044 1.00 32.49  ? 66  ARG F CB  1 
ATOM   3636 C CG  . ARG C 3 66  ? -5.550  -19.490 -13.803 1.00 30.83  ? 66  ARG F CG  1 
ATOM   3637 C CD  . ARG C 3 66  ? -6.743  -20.381 -14.131 1.00 31.03  ? 66  ARG F CD  1 
ATOM   3638 N NE  . ARG C 3 66  ? -6.724  -20.861 -15.508 1.00 32.73  ? 66  ARG F NE  1 
ATOM   3639 C CZ  . ARG C 3 66  ? -6.587  -22.133 -15.857 1.00 33.39  ? 66  ARG F CZ  1 
ATOM   3640 N NH1 . ARG C 3 66  ? -6.472  -23.089 -14.950 1.00 30.56  ? 66  ARG F NH1 1 
ATOM   3641 N NH2 . ARG C 3 66  ? -6.571  -22.454 -17.147 1.00 22.83  ? 66  ARG F NH2 1 
ATOM   3642 N N   . PHE C 3 67  ? -1.155  -19.996 -15.102 1.00 27.42  ? 67  PHE F N   1 
ATOM   3643 C CA  . PHE C 3 67  ? 0.060   -20.697 -15.485 1.00 28.91  ? 67  PHE F CA  1 
ATOM   3644 C C   . PHE C 3 67  ? 1.251   -19.747 -15.436 1.00 33.05  ? 67  PHE F C   1 
ATOM   3645 O O   . PHE C 3 67  ? 1.126   -18.550 -15.707 1.00 29.13  ? 67  PHE F O   1 
ATOM   3646 C CB  . PHE C 3 67  ? -0.053  -21.294 -16.892 1.00 14.74  ? 67  PHE F CB  1 
ATOM   3647 C CG  . PHE C 3 67  ? -1.011  -22.455 -17.003 1.00 19.45  ? 67  PHE F CG  1 
ATOM   3648 C CD1 . PHE C 3 67  ? -1.849  -22.801 -15.956 1.00 27.35  ? 67  PHE F CD1 1 
ATOM   3649 C CD2 . PHE C 3 67  ? -1.059  -23.209 -18.165 1.00 20.86  ? 67  PHE F CD2 1 
ATOM   3650 C CE1 . PHE C 3 67  ? -2.724  -23.866 -16.071 1.00 30.14  ? 67  PHE F CE1 1 
ATOM   3651 C CE2 . PHE C 3 67  ? -1.929  -24.277 -18.284 1.00 26.94  ? 67  PHE F CE2 1 
ATOM   3652 C CZ  . PHE C 3 67  ? -2.762  -24.606 -17.237 1.00 25.12  ? 67  PHE F CZ  1 
ATOM   3653 N N   . THR C 3 68  ? 2.411   -20.295 -15.080 1.00 29.43  ? 68  THR F N   1 
ATOM   3654 C CA  . THR C 3 68  ? 3.668   -19.559 -15.098 1.00 23.99  ? 68  THR F CA  1 
ATOM   3655 C C   . THR C 3 68  ? 4.742   -20.430 -15.729 1.00 29.62  ? 68  THR F C   1 
ATOM   3656 O O   . THR C 3 68  ? 4.955   -21.568 -15.297 1.00 30.14  ? 68  THR F O   1 
ATOM   3657 C CB  . THR C 3 68  ? 4.093   -19.132 -13.688 1.00 31.01  ? 68  THR F CB  1 
ATOM   3658 O OG1 . THR C 3 68  ? 3.116   -18.235 -13.143 1.00 44.20  ? 68  THR F OG1 1 
ATOM   3659 C CG2 . THR C 3 68  ? 5.446   -18.435 -13.726 1.00 20.25  ? 68  THR F CG2 1 
ATOM   3660 N N   . ILE C 3 69  ? 5.413   -19.897 -16.746 1.00 23.46  ? 69  ILE F N   1 
ATOM   3661 C CA  . ILE C 3 69  ? 6.493   -20.594 -17.433 1.00 19.20  ? 69  ILE F CA  1 
ATOM   3662 C C   . ILE C 3 69  ? 7.817   -20.040 -16.930 1.00 24.84  ? 69  ILE F C   1 
ATOM   3663 O O   . ILE C 3 69  ? 7.936   -18.840 -16.646 1.00 24.63  ? 69  ILE F O   1 
ATOM   3664 C CB  . ILE C 3 69  ? 6.366   -20.453 -18.964 1.00 22.19  ? 69  ILE F CB  1 
ATOM   3665 C CG1 . ILE C 3 69  ? 7.440   -21.280 -19.675 1.00 18.52  ? 69  ILE F CG1 1 
ATOM   3666 C CG2 . ILE C 3 69  ? 6.435   -18.990 -19.385 1.00 24.14  ? 69  ILE F CG2 1 
ATOM   3667 C CD1 . ILE C 3 69  ? 7.339   -21.242 -21.182 1.00 21.74  ? 69  ILE F CD1 1 
ATOM   3668 N N   . SER C 3 70  ? 8.808   -20.915 -16.794 1.00 16.50  ? 70  SER F N   1 
ATOM   3669 C CA  . SER C 3 70  ? 10.106  -20.521 -16.267 1.00 23.31  ? 70  SER F CA  1 
ATOM   3670 C C   . SER C 3 70  ? 11.153  -21.505 -16.765 1.00 28.16  ? 70  SER F C   1 
ATOM   3671 O O   . SER C 3 70  ? 10.831  -22.564 -17.310 1.00 26.83  ? 70  SER F O   1 
ATOM   3672 C CB  . SER C 3 70  ? 10.092  -20.458 -14.737 1.00 22.48  ? 70  SER F CB  1 
ATOM   3673 O OG  . SER C 3 70  ? 9.680   -21.696 -14.183 1.00 29.87  ? 70  SER F OG  1 
ATOM   3674 N N   . ARG C 3 71  ? 12.416  -21.135 -16.574 1.00 22.39  ? 71  ARG F N   1 
ATOM   3675 C CA  . ARG C 3 71  ? 13.539  -21.958 -16.993 1.00 25.13  ? 71  ARG F CA  1 
ATOM   3676 C C   . ARG C 3 71  ? 14.608  -21.942 -15.912 1.00 29.43  ? 71  ARG F C   1 
ATOM   3677 O O   . ARG C 3 71  ? 14.711  -20.991 -15.133 1.00 27.43  ? 71  ARG F O   1 
ATOM   3678 C CB  . ARG C 3 71  ? 14.135  -21.468 -18.320 1.00 25.39  ? 71  ARG F CB  1 
ATOM   3679 C CG  . ARG C 3 71  ? 14.685  -20.052 -18.255 1.00 30.80  ? 71  ARG F CG  1 
ATOM   3680 C CD  . ARG C 3 71  ? 15.697  -19.799 -19.357 1.00 39.98  ? 71  ARG F CD  1 
ATOM   3681 N NE  . ARG C 3 71  ? 15.068  -19.501 -20.637 1.00 29.05  ? 71  ARG F NE  1 
ATOM   3682 C CZ  . ARG C 3 71  ? 15.028  -18.295 -21.185 1.00 27.76  ? 71  ARG F CZ  1 
ATOM   3683 N NH1 . ARG C 3 71  ? 15.576  -17.248 -20.592 1.00 23.51  ? 71  ARG F NH1 1 
ATOM   3684 N NH2 . ARG C 3 71  ? 14.427  -18.138 -22.361 1.00 31.24  ? 71  ARG F NH2 1 
ATOM   3685 N N   . ASP C 3 72  ? 15.402  -23.009 -15.870 1.00 41.27  ? 72  ASP F N   1 
ATOM   3686 C CA  . ASP C 3 72  ? 16.561  -23.104 -14.989 1.00 33.54  ? 72  ASP F CA  1 
ATOM   3687 C C   . ASP C 3 72  ? 17.778  -23.385 -15.860 1.00 37.34  ? 72  ASP F C   1 
ATOM   3688 O O   . ASP C 3 72  ? 17.912  -24.483 -16.410 1.00 39.11  ? 72  ASP F O   1 
ATOM   3689 C CB  . ASP C 3 72  ? 16.369  -24.194 -13.935 1.00 41.27  ? 72  ASP F CB  1 
ATOM   3690 C CG  . ASP C 3 72  ? 17.221  -23.966 -12.700 1.00 54.70  ? 72  ASP F CG  1 
ATOM   3691 O OD1 . ASP C 3 72  ? 18.263  -23.285 -12.809 1.00 55.19  ? 72  ASP F OD1 1 
ATOM   3692 O OD2 . ASP C 3 72  ? 16.846  -24.466 -11.619 1.00 63.58  ? 72  ASP F OD2 1 
ATOM   3693 N N   . ASN C 3 73  ? 18.659  -22.390 -15.991 1.00 47.08  ? 73  ASN F N   1 
ATOM   3694 C CA  . ASN C 3 73  ? 19.815  -22.537 -16.871 1.00 35.77  ? 73  ASN F CA  1 
ATOM   3695 C C   . ASN C 3 73  ? 20.759  -23.625 -16.376 1.00 43.73  ? 73  ASN F C   1 
ATOM   3696 O O   . ASN C 3 73  ? 21.276  -24.417 -17.172 1.00 44.96  ? 73  ASN F O   1 
ATOM   3697 C CB  . ASN C 3 73  ? 20.554  -21.205 -16.992 1.00 58.86  ? 73  ASN F CB  1 
ATOM   3698 C CG  . ASN C 3 73  ? 19.633  -20.062 -17.358 1.00 58.87  ? 73  ASN F CG  1 
ATOM   3699 O OD1 . ASN C 3 73  ? 18.545  -20.273 -17.893 1.00 56.50  ? 73  ASN F OD1 1 
ATOM   3700 N ND2 . ASN C 3 73  ? 20.064  -18.839 -17.071 1.00 51.74  ? 73  ASN F ND2 1 
ATOM   3701 N N   . SER C 3 74  ? 21.000  -23.676 -15.063 1.00 46.98  ? 74  SER F N   1 
ATOM   3702 C CA  . SER C 3 74  ? 21.933  -24.659 -14.520 1.00 42.63  ? 74  SER F CA  1 
ATOM   3703 C C   . SER C 3 74  ? 21.431  -26.080 -14.738 1.00 41.32  ? 74  SER F C   1 
ATOM   3704 O O   . SER C 3 74  ? 22.217  -26.984 -15.046 1.00 57.88  ? 74  SER F O   1 
ATOM   3705 C CB  . SER C 3 74  ? 22.168  -24.394 -13.033 1.00 55.24  ? 74  SER F CB  1 
ATOM   3706 O OG  . SER C 3 74  ? 20.976  -24.573 -12.289 1.00 62.94  ? 74  SER F OG  1 
ATOM   3707 N N   . LYS C 3 75  ? 20.127  -26.300 -14.580 1.00 39.74  ? 75  LYS F N   1 
ATOM   3708 C CA  . LYS C 3 75  ? 19.545  -27.620 -14.780 1.00 37.25  ? 75  LYS F CA  1 
ATOM   3709 C C   . LYS C 3 75  ? 19.114  -27.873 -16.219 1.00 35.68  ? 75  LYS F C   1 
ATOM   3710 O O   . LYS C 3 75  ? 18.723  -29.002 -16.536 1.00 26.24  ? 75  LYS F O   1 
ATOM   3711 C CB  . LYS C 3 75  ? 18.345  -27.816 -13.846 1.00 37.21  ? 75  LYS F CB  1 
ATOM   3712 C CG  . LYS C 3 75  ? 18.704  -27.770 -12.370 1.00 44.59  ? 75  LYS F CG  1 
ATOM   3713 C CD  . LYS C 3 75  ? 17.519  -28.146 -11.497 1.00 40.04  ? 75  LYS F CD  1 
ATOM   3714 C CE  . LYS C 3 75  ? 17.911  -28.186 -10.029 1.00 34.31  ? 75  LYS F CE  1 
ATOM   3715 N NZ  . LYS C 3 75  ? 18.423  -26.869 -9.559  1.00 52.64  ? 75  LYS F NZ  1 
ATOM   3716 N N   . SER C 3 76  ? 19.185  -26.862 -17.088 1.00 32.86  ? 76  SER F N   1 
ATOM   3717 C CA  . SER C 3 76  ? 18.801  -26.987 -18.495 1.00 33.24  ? 76  SER F CA  1 
ATOM   3718 C C   . SER C 3 76  ? 17.384  -27.543 -18.626 1.00 27.81  ? 76  SER F C   1 
ATOM   3719 O O   . SER C 3 76  ? 17.119  -28.480 -19.384 1.00 26.86  ? 76  SER F O   1 
ATOM   3720 C CB  . SER C 3 76  ? 19.804  -27.851 -19.260 1.00 28.60  ? 76  SER F CB  1 
ATOM   3721 O OG  . SER C 3 76  ? 19.497  -27.892 -20.642 1.00 32.69  ? 76  SER F OG  1 
ATOM   3722 N N   . THR C 3 77  ? 16.463  -26.953 -17.868 1.00 27.90  ? 77  THR F N   1 
ATOM   3723 C CA  . THR C 3 77  ? 15.108  -27.464 -17.742 1.00 23.63  ? 77  THR F CA  1 
ATOM   3724 C C   . THR C 3 77  ? 14.103  -26.334 -17.911 1.00 24.87  ? 77  THR F C   1 
ATOM   3725 O O   . THR C 3 77  ? 14.324  -25.217 -17.432 1.00 26.97  ? 77  THR F O   1 
ATOM   3726 C CB  . THR C 3 77  ? 14.911  -28.152 -16.381 1.00 28.43  ? 77  THR F CB  1 
ATOM   3727 O OG1 . THR C 3 77  ? 15.850  -29.227 -16.251 1.00 34.00  ? 77  THR F OG1 1 
ATOM   3728 C CG2 . THR C 3 77  ? 13.499  -28.705 -16.245 1.00 24.66  ? 77  THR F CG2 1 
ATOM   3729 N N   . LEU C 3 78  ? 13.005  -26.631 -18.600 1.00 19.31  ? 78  LEU F N   1 
ATOM   3730 C CA  . LEU C 3 78  ? 11.889  -25.711 -18.760 1.00 21.75  ? 78  LEU F CA  1 
ATOM   3731 C C   . LEU C 3 78  ? 10.744  -26.143 -17.854 1.00 19.45  ? 78  LEU F C   1 
ATOM   3732 O O   . LEU C 3 78  ? 10.413  -27.330 -17.779 1.00 23.88  ? 78  LEU F O   1 
ATOM   3733 C CB  . LEU C 3 78  ? 11.421  -25.670 -20.216 1.00 21.02  ? 78  LEU F CB  1 
ATOM   3734 C CG  . LEU C 3 78  ? 10.273  -24.722 -20.569 1.00 22.93  ? 78  LEU F CG  1 
ATOM   3735 C CD1 . LEU C 3 78  ? 10.715  -23.271 -20.469 1.00 21.36  ? 78  LEU F CD1 1 
ATOM   3736 C CD2 . LEU C 3 78  ? 9.740   -25.029 -21.959 1.00 26.92  ? 78  LEU F CD2 1 
ATOM   3737 N N   . TYR C 3 79  ? 10.143  -25.178 -17.164 1.00 20.05  ? 79  TYR F N   1 
ATOM   3738 C CA  . TYR C 3 79  ? 9.083   -25.453 -16.207 1.00 21.61  ? 79  TYR F CA  1 
ATOM   3739 C C   . TYR C 3 79  ? 7.777   -24.811 -16.651 1.00 26.38  ? 79  TYR F C   1 
ATOM   3740 O O   . TYR C 3 79  ? 7.768   -23.758 -17.297 1.00 31.85  ? 79  TYR F O   1 
ATOM   3741 C CB  . TYR C 3 79  ? 9.444   -24.943 -14.806 1.00 23.83  ? 79  TYR F CB  1 
ATOM   3742 C CG  . TYR C 3 79  ? 10.690  -25.560 -14.215 1.00 31.95  ? 79  TYR F CG  1 
ATOM   3743 C CD1 . TYR C 3 79  ? 10.698  -26.881 -13.787 1.00 23.35  ? 79  TYR F CD1 1 
ATOM   3744 C CD2 . TYR C 3 79  ? 11.852  -24.815 -14.066 1.00 30.94  ? 79  TYR F CD2 1 
ATOM   3745 C CE1 . TYR C 3 79  ? 11.835  -27.447 -13.240 1.00 34.76  ? 79  TYR F CE1 1 
ATOM   3746 C CE2 . TYR C 3 79  ? 12.993  -25.372 -13.519 1.00 35.88  ? 79  TYR F CE2 1 
ATOM   3747 C CZ  . TYR C 3 79  ? 12.979  -26.688 -13.108 1.00 40.55  ? 79  TYR F CZ  1 
ATOM   3748 O OH  . TYR C 3 79  ? 14.111  -27.248 -12.563 1.00 45.70  ? 79  TYR F OH  1 
ATOM   3749 N N   . LEU C 3 80  ? 6.670   -25.462 -16.296 1.00 26.45  ? 80  LEU F N   1 
ATOM   3750 C CA  . LEU C 3 80  ? 5.326   -24.918 -16.484 1.00 20.86  ? 80  LEU F CA  1 
ATOM   3751 C C   . LEU C 3 80  ? 4.557   -25.144 -15.187 1.00 25.01  ? 80  LEU F C   1 
ATOM   3752 O O   . LEU C 3 80  ? 4.101   -26.258 -14.914 1.00 23.68  ? 80  LEU F O   1 
ATOM   3753 C CB  . LEU C 3 80  ? 4.615   -25.567 -17.667 1.00 18.42  ? 80  LEU F CB  1 
ATOM   3754 C CG  . LEU C 3 80  ? 3.197   -25.050 -17.927 1.00 23.81  ? 80  LEU F CG  1 
ATOM   3755 C CD1 . LEU C 3 80  ? 3.223   -23.573 -18.296 1.00 20.08  ? 80  LEU F CD1 1 
ATOM   3756 C CD2 . LEU C 3 80  ? 2.510   -25.867 -19.008 1.00 15.85  ? 80  LEU F CD2 1 
ATOM   3757 N N   . GLN C 3 81  ? 4.417   -24.088 -14.391 1.00 29.23  ? 81  GLN F N   1 
ATOM   3758 C CA  . GLN C 3 81  ? 3.679   -24.152 -13.137 1.00 26.40  ? 81  GLN F CA  1 
ATOM   3759 C C   . GLN C 3 81  ? 2.203   -23.904 -13.420 1.00 35.27  ? 81  GLN F C   1 
ATOM   3760 O O   . GLN C 3 81  ? 1.828   -22.820 -13.878 1.00 33.32  ? 81  GLN F O   1 
ATOM   3761 C CB  . GLN C 3 81  ? 4.218   -23.130 -12.137 1.00 25.12  ? 81  GLN F CB  1 
ATOM   3762 C CG  . GLN C 3 81  ? 3.484   -23.125 -10.807 1.00 27.87  ? 81  GLN F CG  1 
ATOM   3763 C CD  . GLN C 3 81  ? 3.600   -24.449 -10.078 1.00 24.59  ? 81  GLN F CD  1 
ATOM   3764 O OE1 . GLN C 3 81  ? 4.680   -25.031 -9.994  1.00 24.56  ? 81  GLN F OE1 1 
ATOM   3765 N NE2 . GLN C 3 81  ? 2.482   -24.935 -9.551  1.00 31.49  ? 81  GLN F NE2 1 
ATOM   3766 N N   . MET C 3 82  ? 1.372   -24.905 -13.146 1.00 33.64  ? 82  MET F N   1 
ATOM   3767 C CA  . MET C 3 82  ? -0.058  -24.847 -13.421 1.00 35.50  ? 82  MET F CA  1 
ATOM   3768 C C   . MET C 3 82  ? -0.812  -24.784 -12.100 1.00 37.15  ? 82  MET F C   1 
ATOM   3769 O O   . MET C 3 82  ? -0.662  -25.672 -11.254 1.00 44.41  ? 82  MET F O   1 
ATOM   3770 C CB  . MET C 3 82  ? -0.497  -26.057 -14.246 1.00 31.47  ? 82  MET F CB  1 
ATOM   3771 C CG  . MET C 3 82  ? 0.413   -26.335 -15.435 1.00 38.41  ? 82  MET F CG  1 
ATOM   3772 S SD  . MET C 3 82  ? -0.276  -27.490 -16.637 1.00 37.35  ? 82  MET F SD  1 
ATOM   3773 C CE  . MET C 3 82  ? -0.064  -29.052 -15.790 1.00 41.57  ? 82  MET F CE  1 
ATOM   3774 N N   . ASN C 3 83  A -1.617  -23.739 -11.928 1.00 28.17  ? 82  ASN F N   1 
ATOM   3775 C CA  . ASN C 3 83  A -2.405  -23.541 -10.722 1.00 33.15  ? 82  ASN F CA  1 
ATOM   3776 C C   . ASN C 3 83  A -3.861  -23.319 -11.103 1.00 43.26  ? 82  ASN F C   1 
ATOM   3777 O O   . ASN C 3 83  A -4.174  -22.922 -12.229 1.00 43.50  ? 82  ASN F O   1 
ATOM   3778 C CB  . ASN C 3 83  A -1.895  -22.349 -9.897  1.00 31.33  ? 82  ASN F CB  1 
ATOM   3779 C CG  . ASN C 3 83  A -0.441  -22.495 -9.496  1.00 41.74  ? 82  ASN F CG  1 
ATOM   3780 O OD1 . ASN C 3 83  A 0.062   -23.606 -9.329  1.00 37.53  ? 82  ASN F OD1 1 
ATOM   3781 N ND2 . ASN C 3 83  A 0.244   -21.368 -9.336  1.00 32.05  ? 82  ASN F ND2 1 
ATOM   3782 N N   . SER C 3 84  B -4.749  -23.576 -10.142 1.00 40.36  ? 82  SER F N   1 
ATOM   3783 C CA  . SER C 3 84  B -6.192  -23.415 -10.331 1.00 26.48  ? 82  SER F CA  1 
ATOM   3784 C C   . SER C 3 84  B -6.670  -24.192 -11.555 1.00 26.59  ? 82  SER F C   1 
ATOM   3785 O O   . SER C 3 84  B -7.416  -23.687 -12.397 1.00 34.76  ? 82  SER F O   1 
ATOM   3786 C CB  . SER C 3 84  B -6.567  -21.936 -10.435 1.00 27.07  ? 82  SER F CB  1 
ATOM   3787 O OG  . SER C 3 84  B -6.102  -21.210 -9.311  1.00 45.29  ? 82  SER F OG  1 
ATOM   3788 N N   . LEU C 3 85  C -6.221  -25.442 -11.648 1.00 29.26  ? 82  LEU F N   1 
ATOM   3789 C CA  . LEU C 3 85  C -6.497  -26.262 -12.819 1.00 31.99  ? 82  LEU F CA  1 
ATOM   3790 C C   . LEU C 3 85  C -7.994  -26.503 -12.978 1.00 32.85  ? 82  LEU F C   1 
ATOM   3791 O O   . LEU C 3 85  C -8.738  -26.635 -12.002 1.00 37.39  ? 82  LEU F O   1 
ATOM   3792 C CB  . LEU C 3 85  C -5.760  -27.596 -12.717 1.00 35.20  ? 82  LEU F CB  1 
ATOM   3793 C CG  . LEU C 3 85  C -4.251  -27.523 -12.960 1.00 42.65  ? 82  LEU F CG  1 
ATOM   3794 C CD1 . LEU C 3 85  C -3.558  -28.773 -12.453 1.00 39.77  ? 82  LEU F CD1 1 
ATOM   3795 C CD2 . LEU C 3 85  C -3.966  -27.317 -14.440 1.00 34.43  ? 82  LEU F CD2 1 
ATOM   3796 N N   . ARG C 3 86  ? -8.428  -26.554 -14.233 1.00 31.45  ? 83  ARG F N   1 
ATOM   3797 C CA  . ARG C 3 86  ? -9.819  -26.764 -14.600 1.00 29.36  ? 83  ARG F CA  1 
ATOM   3798 C C   . ARG C 3 86  ? -9.938  -28.036 -15.427 1.00 37.60  ? 83  ARG F C   1 
ATOM   3799 O O   . ARG C 3 86  ? -8.947  -28.582 -15.919 1.00 42.93  ? 83  ARG F O   1 
ATOM   3800 C CB  . ARG C 3 86  ? -10.364 -25.565 -15.384 1.00 30.96  ? 83  ARG F CB  1 
ATOM   3801 C CG  . ARG C 3 86  ? -10.167 -24.228 -14.690 1.00 34.97  ? 83  ARG F CG  1 
ATOM   3802 C CD  . ARG C 3 86  ? -10.274 -23.085 -15.682 1.00 36.19  ? 83  ARG F CD  1 
ATOM   3803 N NE  . ARG C 3 86  ? -10.177 -21.781 -15.038 1.00 49.62  ? 83  ARG F NE  1 
ATOM   3804 C CZ  . ARG C 3 86  ? -10.158 -20.626 -15.689 1.00 44.95  ? 83  ARG F CZ  1 
ATOM   3805 N NH1 . ARG C 3 86  ? -10.212 -20.577 -17.010 1.00 31.42  ? 83  ARG F NH1 1 
ATOM   3806 N NH2 . ARG C 3 86  ? -10.083 -19.493 -14.998 1.00 41.43  ? 83  ARG F NH2 1 
ATOM   3807 N N   . VAL C 3 87  ? -11.179 -28.502 -15.583 1.00 33.89  ? 84  VAL F N   1 
ATOM   3808 C CA  . VAL C 3 87  ? -11.427 -29.717 -16.354 1.00 40.69  ? 84  VAL F CA  1 
ATOM   3809 C C   . VAL C 3 87  ? -11.000 -29.527 -17.804 1.00 42.36  ? 84  VAL F C   1 
ATOM   3810 O O   . VAL C 3 87  ? -10.458 -30.445 -18.433 1.00 42.06  ? 84  VAL F O   1 
ATOM   3811 C CB  . VAL C 3 87  ? -12.908 -30.126 -16.244 1.00 36.65  ? 84  VAL F CB  1 
ATOM   3812 C CG1 . VAL C 3 87  ? -13.201 -31.328 -17.129 1.00 22.41  ? 84  VAL F CG1 1 
ATOM   3813 C CG2 . VAL C 3 87  ? -13.265 -30.428 -14.797 1.00 22.37  ? 84  VAL F CG2 1 
ATOM   3814 N N   . GLU C 3 88  ? -11.220 -28.330 -18.355 1.00 42.75  ? 85  GLU F N   1 
ATOM   3815 C CA  . GLU C 3 88  ? -10.856 -28.064 -19.742 1.00 42.62  ? 85  GLU F CA  1 
ATOM   3816 C C   . GLU C 3 88  ? -9.350  -27.981 -19.956 1.00 39.54  ? 85  GLU F C   1 
ATOM   3817 O O   . GLU C 3 88  ? -8.912  -27.922 -21.110 1.00 48.78  ? 85  GLU F O   1 
ATOM   3818 C CB  . GLU C 3 88  ? -11.518 -26.773 -20.231 1.00 42.32  ? 85  GLU F CB  1 
ATOM   3819 C CG  . GLU C 3 88  ? -11.159 -25.529 -19.435 1.00 44.29  ? 85  GLU F CG  1 
ATOM   3820 C CD  . GLU C 3 88  ? -12.169 -25.218 -18.349 1.00 53.20  ? 85  GLU F CD  1 
ATOM   3821 O OE1 . GLU C 3 88  ? -12.838 -26.157 -17.867 1.00 49.19  ? 85  GLU F OE1 1 
ATOM   3822 O OE2 . GLU C 3 88  ? -12.301 -24.031 -17.983 1.00 60.04  ? 85  GLU F OE2 1 
ATOM   3823 N N   . ASP C 3 89  ? -8.553  -27.971 -18.889 1.00 38.62  ? 86  ASP F N   1 
ATOM   3824 C CA  . ASP C 3 89  ? -7.102  -28.010 -19.015 1.00 30.54  ? 86  ASP F CA  1 
ATOM   3825 C C   . ASP C 3 89  ? -6.570  -29.418 -19.249 1.00 25.93  ? 86  ASP F C   1 
ATOM   3826 O O   . ASP C 3 89  ? -5.355  -29.586 -19.397 1.00 33.40  ? 86  ASP F O   1 
ATOM   3827 C CB  . ASP C 3 89  ? -6.443  -27.410 -17.770 1.00 20.55  ? 86  ASP F CB  1 
ATOM   3828 C CG  . ASP C 3 89  ? -6.649  -25.912 -17.665 1.00 28.24  ? 86  ASP F CG  1 
ATOM   3829 O OD1 . ASP C 3 89  ? -6.685  -25.239 -18.717 1.00 37.66  ? 86  ASP F OD1 1 
ATOM   3830 O OD2 . ASP C 3 89  ? -6.774  -25.404 -16.531 1.00 29.00  ? 86  ASP F OD2 1 
ATOM   3831 N N   . THR C 3 90  ? -7.442  -30.424 -19.278 1.00 27.82  ? 87  THR F N   1 
ATOM   3832 C CA  . THR C 3 90  ? -7.019  -31.793 -19.548 1.00 29.03  ? 87  THR F CA  1 
ATOM   3833 C C   . THR C 3 90  ? -6.525  -31.905 -20.984 1.00 32.24  ? 87  THR F C   1 
ATOM   3834 O O   . THR C 3 90  ? -7.301  -31.732 -21.930 1.00 47.57  ? 87  THR F O   1 
ATOM   3835 C CB  . THR C 3 90  ? -8.174  -32.762 -19.305 1.00 24.76  ? 87  THR F CB  1 
ATOM   3836 O OG1 . THR C 3 90  ? -8.585  -32.686 -17.934 1.00 31.28  ? 87  THR F OG1 1 
ATOM   3837 C CG2 . THR C 3 90  ? -7.752  -34.188 -19.627 1.00 15.19  ? 87  THR F CG2 1 
ATOM   3838 N N   . ALA C 3 91  ? -5.238  -32.200 -21.147 1.00 31.59  ? 88  ALA F N   1 
ATOM   3839 C CA  . ALA C 3 91  ? -4.625  -32.281 -22.467 1.00 31.60  ? 88  ALA F CA  1 
ATOM   3840 C C   . ALA C 3 91  ? -3.250  -32.917 -22.326 1.00 27.91  ? 88  ALA F C   1 
ATOM   3841 O O   . ALA C 3 91  ? -2.723  -33.067 -21.221 1.00 27.45  ? 88  ALA F O   1 
ATOM   3842 C CB  . ALA C 3 91  ? -4.515  -30.902 -23.122 1.00 28.21  ? 88  ALA F CB  1 
ATOM   3843 N N   . VAL C 3 92  ? -2.680  -33.294 -23.466 1.00 23.25  ? 89  VAL F N   1 
ATOM   3844 C CA  . VAL C 3 92  ? -1.278  -33.684 -23.545 1.00 25.82  ? 89  VAL F CA  1 
ATOM   3845 C C   . VAL C 3 92  ? -0.462  -32.419 -23.770 1.00 27.08  ? 89  VAL F C   1 
ATOM   3846 O O   . VAL C 3 92  ? -0.675  -31.699 -24.751 1.00 28.74  ? 89  VAL F O   1 
ATOM   3847 C CB  . VAL C 3 92  ? -1.038  -34.700 -24.670 1.00 26.49  ? 89  VAL F CB  1 
ATOM   3848 C CG1 . VAL C 3 92  ? 0.453   -34.900 -24.889 1.00 26.81  ? 89  VAL F CG1 1 
ATOM   3849 C CG2 . VAL C 3 92  ? -1.712  -36.021 -24.342 1.00 24.81  ? 89  VAL F CG2 1 
ATOM   3850 N N   . TYR C 3 93  ? 0.467   -32.143 -22.862 1.00 26.52  ? 90  TYR F N   1 
ATOM   3851 C CA  . TYR C 3 93  ? 1.262   -30.923 -22.905 1.00 20.20  ? 90  TYR F CA  1 
ATOM   3852 C C   . TYR C 3 93  ? 2.612   -31.226 -23.540 1.00 22.68  ? 90  TYR F C   1 
ATOM   3853 O O   . TYR C 3 93  ? 3.345   -32.102 -23.067 1.00 24.08  ? 90  TYR F O   1 
ATOM   3854 C CB  . TYR C 3 93  ? 1.432   -30.340 -21.504 1.00 18.55  ? 90  TYR F CB  1 
ATOM   3855 C CG  . TYR C 3 93  ? 0.187   -29.655 -20.992 1.00 25.77  ? 90  TYR F CG  1 
ATOM   3856 C CD1 . TYR C 3 93  ? -0.926  -30.391 -20.606 1.00 22.86  ? 90  TYR F CD1 1 
ATOM   3857 C CD2 . TYR C 3 93  ? 0.121   -28.271 -20.902 1.00 18.37  ? 90  TYR F CD2 1 
ATOM   3858 C CE1 . TYR C 3 93  ? -2.069  -29.768 -20.143 1.00 21.64  ? 90  TYR F CE1 1 
ATOM   3859 C CE2 . TYR C 3 93  ? -1.016  -27.639 -20.438 1.00 21.72  ? 90  TYR F CE2 1 
ATOM   3860 C CZ  . TYR C 3 93  ? -2.108  -28.392 -20.060 1.00 24.49  ? 90  TYR F CZ  1 
ATOM   3861 O OH  . TYR C 3 93  ? -3.243  -27.768 -19.598 1.00 31.82  ? 90  TYR F OH  1 
ATOM   3862 N N   . TYR C 3 94  ? 2.934   -30.503 -24.608 1.00 27.04  ? 91  TYR F N   1 
ATOM   3863 C CA  . TYR C 3 94  ? 4.160   -30.714 -25.363 1.00 21.89  ? 91  TYR F CA  1 
ATOM   3864 C C   . TYR C 3 94  ? 5.167   -29.619 -25.045 1.00 19.53  ? 91  TYR F C   1 
ATOM   3865 O O   . TYR C 3 94  ? 4.829   -28.431 -25.061 1.00 23.95  ? 91  TYR F O   1 
ATOM   3866 C CB  . TYR C 3 94  ? 3.887   -30.734 -26.868 1.00 21.82  ? 91  TYR F CB  1 
ATOM   3867 C CG  . TYR C 3 94  ? 3.167   -31.965 -27.363 1.00 24.64  ? 91  TYR F CG  1 
ATOM   3868 C CD1 . TYR C 3 94  ? 3.836   -33.174 -27.498 1.00 21.59  ? 91  TYR F CD1 1 
ATOM   3869 C CD2 . TYR C 3 94  ? 1.826   -31.915 -27.714 1.00 14.71  ? 91  TYR F CD2 1 
ATOM   3870 C CE1 . TYR C 3 94  ? 3.187   -34.301 -27.957 1.00 22.40  ? 91  TYR F CE1 1 
ATOM   3871 C CE2 . TYR C 3 94  ? 1.168   -33.038 -28.176 1.00 21.03  ? 91  TYR F CE2 1 
ATOM   3872 C CZ  . TYR C 3 94  ? 1.853   -34.228 -28.294 1.00 21.08  ? 91  TYR F CZ  1 
ATOM   3873 O OH  . TYR C 3 94  ? 1.204   -35.351 -28.752 1.00 32.75  ? 91  TYR F OH  1 
ATOM   3874 N N   . CYS C 3 95  ? 6.395   -30.027 -24.746 1.00 23.39  ? 92  CYS F N   1 
ATOM   3875 C CA  . CYS C 3 95  ? 7.526   -29.114 -24.734 1.00 20.59  ? 92  CYS F CA  1 
ATOM   3876 C C   . CYS C 3 95  ? 8.014   -28.931 -26.164 1.00 25.42  ? 92  CYS F C   1 
ATOM   3877 O O   . CYS C 3 95  ? 8.160   -29.907 -26.907 1.00 25.87  ? 92  CYS F O   1 
ATOM   3878 C CB  . CYS C 3 95  ? 8.638   -29.671 -23.849 1.00 26.35  ? 92  CYS F CB  1 
ATOM   3879 S SG  . CYS C 3 95  ? 10.038  -28.587 -23.541 1.00 60.51  ? 92  CYS F SG  1 
ATOM   3880 N N   . ALA C 3 96  ? 8.254   -27.684 -26.561 1.00 15.56  ? 93  ALA F N   1 
ATOM   3881 C CA  . ALA C 3 96  ? 8.610   -27.398 -27.943 1.00 26.02  ? 93  ALA F CA  1 
ATOM   3882 C C   . ALA C 3 96  ? 9.686   -26.328 -28.002 1.00 26.72  ? 93  ALA F C   1 
ATOM   3883 O O   . ALA C 3 96  ? 9.580   -25.297 -27.332 1.00 20.71  ? 93  ALA F O   1 
ATOM   3884 C CB  . ALA C 3 96  ? 7.383   -26.952 -28.747 1.00 23.94  ? 93  ALA F CB  1 
ATOM   3885 N N   . ARG C 3 97  ? 10.713  -26.579 -28.810 1.00 27.43  ? 94  ARG F N   1 
ATOM   3886 C CA  . ARG C 3 97  ? 11.716  -25.566 -29.101 1.00 28.74  ? 94  ARG F CA  1 
ATOM   3887 C C   . ARG C 3 97  ? 11.141  -24.573 -30.101 1.00 28.06  ? 94  ARG F C   1 
ATOM   3888 O O   . ARG C 3 97  ? 10.641  -24.962 -31.160 1.00 32.96  ? 94  ARG F O   1 
ATOM   3889 C CB  . ARG C 3 97  ? 12.989  -26.212 -29.648 1.00 30.37  ? 94  ARG F CB  1 
ATOM   3890 C CG  . ARG C 3 97  ? 14.156  -25.253 -29.824 1.00 28.04  ? 94  ARG F CG  1 
ATOM   3891 C CD  . ARG C 3 97  ? 15.466  -26.016 -29.933 1.00 36.79  ? 94  ARG F CD  1 
ATOM   3892 N NE  . ARG C 3 97  ? 16.609  -25.132 -30.125 1.00 42.32  ? 94  ARG F NE  1 
ATOM   3893 C CZ  . ARG C 3 97  ? 17.216  -24.935 -31.287 1.00 45.99  ? 94  ARG F CZ  1 
ATOM   3894 N NH1 . ARG C 3 97  ? 16.821  -25.555 -32.386 1.00 48.31  ? 94  ARG F NH1 1 
ATOM   3895 N NH2 . ARG C 3 97  ? 18.246  -24.097 -31.346 1.00 40.82  ? 94  ARG F NH2 1 
ATOM   3896 N N   . ASP C 3 98  ? 11.206  -23.293 -29.759 1.00 23.41  ? 95  ASP F N   1 
ATOM   3897 C CA  . ASP C 3 98  ? 10.556  -22.238 -30.522 1.00 28.45  ? 95  ASP F CA  1 
ATOM   3898 C C   . ASP C 3 98  ? 11.611  -21.419 -31.252 1.00 29.58  ? 95  ASP F C   1 
ATOM   3899 O O   . ASP C 3 98  ? 12.587  -20.972 -30.640 1.00 31.39  ? 95  ASP F O   1 
ATOM   3900 C CB  . ASP C 3 98  ? 9.728   -21.344 -29.596 1.00 21.91  ? 95  ASP F CB  1 
ATOM   3901 C CG  . ASP C 3 98  ? 8.582   -20.663 -30.311 1.00 39.59  ? 95  ASP F CG  1 
ATOM   3902 O OD1 . ASP C 3 98  ? 8.617   -20.583 -31.557 1.00 40.95  ? 95  ASP F OD1 1 
ATOM   3903 O OD2 . ASP C 3 98  ? 7.645   -20.206 -29.622 1.00 38.68  ? 95  ASP F OD2 1 
ATOM   3904 N N   . PHE C 3 99  ? 11.422  -21.231 -32.557 1.00 28.28  ? 96  PHE F N   1 
ATOM   3905 C CA  . PHE C 3 99  ? 12.340  -20.421 -33.357 1.00 20.60  ? 96  PHE F CA  1 
ATOM   3906 C C   . PHE C 3 99  ? 11.801  -18.998 -33.418 1.00 23.91  ? 96  PHE F C   1 
ATOM   3907 O O   . PHE C 3 99  ? 10.938  -18.683 -34.241 1.00 30.10  ? 96  PHE F O   1 
ATOM   3908 C CB  . PHE C 3 99  ? 12.518  -21.003 -34.755 1.00 25.31  ? 96  PHE F CB  1 
ATOM   3909 C CG  . PHE C 3 99  ? 13.521  -20.257 -35.592 1.00 30.26  ? 96  PHE F CG  1 
ATOM   3910 C CD1 . PHE C 3 99  ? 14.866  -20.581 -35.535 1.00 31.63  ? 96  PHE F CD1 1 
ATOM   3911 C CD2 . PHE C 3 99  ? 13.121  -19.222 -36.425 1.00 26.59  ? 96  PHE F CD2 1 
ATOM   3912 C CE1 . PHE C 3 99  ? 15.794  -19.894 -36.297 1.00 29.89  ? 96  PHE F CE1 1 
ATOM   3913 C CE2 . PHE C 3 99  ? 14.045  -18.530 -37.188 1.00 25.97  ? 96  PHE F CE2 1 
ATOM   3914 C CZ  . PHE C 3 99  ? 15.383  -18.867 -37.125 1.00 23.65  ? 96  PHE F CZ  1 
ATOM   3915 N N   . GLY C 3 100 ? 12.309  -18.138 -32.541 1.00 25.92  ? 97  GLY F N   1 
ATOM   3916 C CA  . GLY C 3 100 ? 11.980  -16.722 -32.594 1.00 24.62  ? 97  GLY F CA  1 
ATOM   3917 C C   . GLY C 3 100 ? 10.505  -16.418 -32.461 1.00 24.15  ? 97  GLY F C   1 
ATOM   3918 O O   . GLY C 3 100 ? 10.005  -15.491 -33.111 1.00 37.73  ? 97  GLY F O   1 
ATOM   3919 N N   . ASP C 3 101 ? 9.793   -17.183 -31.630 1.00 24.51  ? 98  ASP F N   1 
ATOM   3920 C CA  . ASP C 3 101 ? 8.357   -17.001 -31.413 1.00 32.26  ? 98  ASP F CA  1 
ATOM   3921 C C   . ASP C 3 101 ? 7.569   -17.144 -32.714 1.00 30.47  ? 98  ASP F C   1 
ATOM   3922 O O   . ASP C 3 101 ? 6.527   -16.510 -32.896 1.00 27.50  ? 98  ASP F O   1 
ATOM   3923 C CB  . ASP C 3 101 ? 8.069   -15.648 -30.749 1.00 32.54  ? 98  ASP F CB  1 
ATOM   3924 C CG  . ASP C 3 101 ? 6.689   -15.578 -30.122 1.00 41.00  ? 98  ASP F CG  1 
ATOM   3925 O OD1 . ASP C 3 101 ? 6.044   -16.636 -29.969 1.00 46.69  ? 98  ASP F OD1 1 
ATOM   3926 O OD2 . ASP C 3 101 ? 6.247   -14.458 -29.787 1.00 36.41  ? 98  ASP F OD2 1 
ATOM   3927 N N   . PHE C 3 102 ? 8.059   -17.975 -33.637 1.00 34.21  ? 99  PHE F N   1 
ATOM   3928 C CA  . PHE C 3 102 ? 7.394   -18.191 -34.916 1.00 28.41  ? 99  PHE F CA  1 
ATOM   3929 C C   . PHE C 3 102 ? 6.868   -19.613 -35.063 1.00 24.26  ? 99  PHE F C   1 
ATOM   3930 O O   . PHE C 3 102 ? 5.659   -19.816 -35.203 1.00 28.22  ? 99  PHE F O   1 
ATOM   3931 C CB  . PHE C 3 102 ? 8.354   -17.872 -36.072 1.00 23.31  ? 99  PHE F CB  1 
ATOM   3932 C CG  . PHE C 3 102 ? 8.663   -16.411 -36.227 1.00 27.26  ? 99  PHE F CG  1 
ATOM   3933 C CD1 . PHE C 3 102 ? 7.815   -15.446 -35.708 1.00 26.82  ? 99  PHE F CD1 1 
ATOM   3934 C CD2 . PHE C 3 102 ? 9.802   -16.004 -36.903 1.00 20.87  ? 99  PHE F CD2 1 
ATOM   3935 C CE1 . PHE C 3 102 ? 8.100   -14.101 -35.855 1.00 33.93  ? 99  PHE F CE1 1 
ATOM   3936 C CE2 . PHE C 3 102 ? 10.093  -14.662 -37.054 1.00 31.76  ? 99  PHE F CE2 1 
ATOM   3937 C CZ  . PHE C 3 102 ? 9.241   -13.708 -36.530 1.00 43.02  ? 99  PHE F CZ  1 
ATOM   3938 N N   . TYR C 3 103 ? 7.744   -20.612 -35.000 1.00 21.83  ? 100 TYR F N   1 
ATOM   3939 C CA  . TYR C 3 103 ? 7.340   -21.986 -35.258 1.00 24.78  ? 100 TYR F CA  1 
ATOM   3940 C C   . TYR C 3 103 ? 8.158   -22.921 -34.382 1.00 29.00  ? 100 TYR F C   1 
ATOM   3941 O O   . TYR C 3 103 ? 9.232   -22.566 -33.888 1.00 33.50  ? 100 TYR F O   1 
ATOM   3942 C CB  . TYR C 3 103 ? 7.489   -22.354 -36.743 1.00 18.01  ? 100 TYR F CB  1 
ATOM   3943 C CG  . TYR C 3 103 ? 8.867   -22.117 -37.321 1.00 31.65  ? 100 TYR F CG  1 
ATOM   3944 C CD1 . TYR C 3 103 ? 9.206   -20.893 -37.886 1.00 28.18  ? 100 TYR F CD1 1 
ATOM   3945 C CD2 . TYR C 3 103 ? 9.826   -23.123 -37.314 1.00 26.52  ? 100 TYR F CD2 1 
ATOM   3946 C CE1 . TYR C 3 103 ? 10.464  -20.674 -38.420 1.00 22.17  ? 100 TYR F CE1 1 
ATOM   3947 C CE2 . TYR C 3 103 ? 11.085  -22.914 -37.845 1.00 26.83  ? 100 TYR F CE2 1 
ATOM   3948 C CZ  . TYR C 3 103 ? 11.399  -21.689 -38.397 1.00 33.59  ? 100 TYR F CZ  1 
ATOM   3949 O OH  . TYR C 3 103 ? 12.653  -21.479 -38.926 1.00 28.86  ? 100 TYR F OH  1 
ATOM   3950 N N   . PHE C 3 104 A 7.630   -24.125 -34.197 1.00 26.72  ? 100 PHE F N   1 
ATOM   3951 C CA  . PHE C 3 104 A 8.174   -25.105 -33.262 1.00 24.06  ? 100 PHE F CA  1 
ATOM   3952 C C   . PHE C 3 104 A 8.898   -26.182 -34.063 1.00 32.77  ? 100 PHE F C   1 
ATOM   3953 O O   . PHE C 3 104 A 8.267   -27.082 -34.625 1.00 30.13  ? 100 PHE F O   1 
ATOM   3954 C CB  . PHE C 3 104 A 7.053   -25.683 -32.403 1.00 23.32  ? 100 PHE F CB  1 
ATOM   3955 C CG  . PHE C 3 104 A 6.065   -24.651 -31.934 1.00 22.54  ? 100 PHE F CG  1 
ATOM   3956 C CD1 . PHE C 3 104 A 6.340   -23.859 -30.832 1.00 26.68  ? 100 PHE F CD1 1 
ATOM   3957 C CD2 . PHE C 3 104 A 4.867   -24.463 -32.605 1.00 25.17  ? 100 PHE F CD2 1 
ATOM   3958 C CE1 . PHE C 3 104 A 5.436   -22.902 -30.404 1.00 30.37  ? 100 PHE F CE1 1 
ATOM   3959 C CE2 . PHE C 3 104 A 3.958   -23.509 -32.181 1.00 29.73  ? 100 PHE F CE2 1 
ATOM   3960 C CZ  . PHE C 3 104 A 4.243   -22.728 -31.078 1.00 31.52  ? 100 PHE F CZ  1 
ATOM   3961 N N   . ASP C 3 105 ? 10.230  -26.086 -34.109 1.00 28.64  ? 101 ASP F N   1 
ATOM   3962 C CA  . ASP C 3 105 ? 11.029  -26.991 -34.928 1.00 31.11  ? 101 ASP F CA  1 
ATOM   3963 C C   . ASP C 3 105 ? 11.338  -28.313 -34.237 1.00 31.84  ? 101 ASP F C   1 
ATOM   3964 O O   . ASP C 3 105 ? 11.596  -29.307 -34.926 1.00 41.24  ? 101 ASP F O   1 
ATOM   3965 C CB  . ASP C 3 105 ? 12.333  -26.306 -35.349 1.00 30.48  ? 101 ASP F CB  1 
ATOM   3966 C CG  . ASP C 3 105 ? 13.050  -25.644 -34.188 1.00 46.92  ? 101 ASP F CG  1 
ATOM   3967 O OD1 . ASP C 3 105 ? 12.549  -25.729 -33.048 1.00 45.24  ? 101 ASP F OD1 1 
ATOM   3968 O OD2 . ASP C 3 105 ? 14.116  -25.034 -34.418 1.00 52.93  ? 101 ASP F OD2 1 
ATOM   3969 N N   . TYR C 3 106 ? 11.326  -28.355 -32.907 1.00 29.46  ? 102 TYR F N   1 
ATOM   3970 C CA  . TYR C 3 106 ? 11.552  -29.589 -32.167 1.00 33.11  ? 102 TYR F CA  1 
ATOM   3971 C C   . TYR C 3 106 ? 10.496  -29.734 -31.083 1.00 23.88  ? 102 TYR F C   1 
ATOM   3972 O O   . TYR C 3 106 ? 10.124  -28.754 -30.431 1.00 25.92  ? 102 TYR F O   1 
ATOM   3973 C CB  . TYR C 3 106 ? 12.956  -29.627 -31.551 1.00 35.59  ? 102 TYR F CB  1 
ATOM   3974 C CG  . TYR C 3 106 ? 14.065  -29.698 -32.577 1.00 39.77  ? 102 TYR F CG  1 
ATOM   3975 C CD1 . TYR C 3 106 ? 14.393  -30.901 -33.189 1.00 36.92  ? 102 TYR F CD1 1 
ATOM   3976 C CD2 . TYR C 3 106 ? 14.782  -28.563 -32.934 1.00 39.00  ? 102 TYR F CD2 1 
ATOM   3977 C CE1 . TYR C 3 106 ? 15.404  -30.972 -34.129 1.00 36.07  ? 102 TYR F CE1 1 
ATOM   3978 C CE2 . TYR C 3 106 ? 15.796  -28.624 -33.873 1.00 35.23  ? 102 TYR F CE2 1 
ATOM   3979 C CZ  . TYR C 3 106 ? 16.103  -29.831 -34.466 1.00 41.22  ? 102 TYR F CZ  1 
ATOM   3980 O OH  . TYR C 3 106 ? 17.111  -29.896 -35.401 1.00 47.71  ? 102 TYR F OH  1 
ATOM   3981 N N   . TRP C 3 107 ? 10.019  -30.963 -30.894 1.00 29.89  ? 103 TRP F N   1 
ATOM   3982 C CA  . TRP C 3 107 ? 8.951   -31.264 -29.951 1.00 25.50  ? 103 TRP F CA  1 
ATOM   3983 C C   . TRP C 3 107 ? 9.364   -32.419 -29.052 1.00 27.39  ? 103 TRP F C   1 
ATOM   3984 O O   . TRP C 3 107 ? 10.052  -33.345 -29.491 1.00 38.68  ? 103 TRP F O   1 
ATOM   3985 C CB  . TRP C 3 107 ? 7.647   -31.636 -30.676 1.00 31.30  ? 103 TRP F CB  1 
ATOM   3986 C CG  . TRP C 3 107 ? 7.043   -30.539 -31.501 1.00 29.48  ? 103 TRP F CG  1 
ATOM   3987 C CD1 . TRP C 3 107 ? 7.579   -29.957 -32.611 1.00 28.33  ? 103 TRP F CD1 1 
ATOM   3988 C CD2 . TRP C 3 107 ? 5.769   -29.915 -31.296 1.00 30.81  ? 103 TRP F CD2 1 
ATOM   3989 N NE1 . TRP C 3 107 ? 6.726   -28.997 -33.101 1.00 26.45  ? 103 TRP F NE1 1 
ATOM   3990 C CE2 . TRP C 3 107 ? 5.607   -28.953 -32.312 1.00 31.41  ? 103 TRP F CE2 1 
ATOM   3991 C CE3 . TRP C 3 107 ? 4.753   -30.072 -30.348 1.00 21.20  ? 103 TRP F CE3 1 
ATOM   3992 C CZ2 . TRP C 3 107 ? 4.470   -28.152 -32.408 1.00 28.56  ? 103 TRP F CZ2 1 
ATOM   3993 C CZ3 . TRP C 3 107 ? 3.626   -29.276 -30.444 1.00 31.64  ? 103 TRP F CZ3 1 
ATOM   3994 C CH2 . TRP C 3 107 ? 3.494   -28.328 -31.466 1.00 26.70  ? 103 TRP F CH2 1 
ATOM   3995 N N   . GLY C 3 108 ? 8.939   -32.359 -27.790 1.00 27.91  ? 104 GLY F N   1 
ATOM   3996 C CA  . GLY C 3 108 ? 9.051   -33.505 -26.915 1.00 34.11  ? 104 GLY F CA  1 
ATOM   3997 C C   . GLY C 3 108 ? 7.885   -34.459 -27.095 1.00 30.18  ? 104 GLY F C   1 
ATOM   3998 O O   . GLY C 3 108 ? 6.866   -34.127 -27.696 1.00 36.55  ? 104 GLY F O   1 
ATOM   3999 N N   . GLN C 3 109 ? 8.040   -35.669 -26.550 1.00 37.32  ? 105 GLN F N   1 
ATOM   4000 C CA  . GLN C 3 109 ? 7.008   -36.684 -26.735 1.00 37.28  ? 105 GLN F CA  1 
ATOM   4001 C C   . GLN C 3 109 ? 5.730   -36.367 -25.965 1.00 34.97  ? 105 GLN F C   1 
ATOM   4002 O O   . GLN C 3 109 ? 4.690   -36.972 -26.244 1.00 30.86  ? 105 GLN F O   1 
ATOM   4003 C CB  . GLN C 3 109 ? 7.532   -38.065 -26.332 1.00 35.38  ? 105 GLN F CB  1 
ATOM   4004 C CG  . GLN C 3 109 ? 7.559   -38.320 -24.836 1.00 54.62  ? 105 GLN F CG  1 
ATOM   4005 C CD  . GLN C 3 109 ? 8.791   -37.751 -24.163 1.00 56.85  ? 105 GLN F CD  1 
ATOM   4006 O OE1 . GLN C 3 109 ? 9.845   -37.613 -24.785 1.00 47.28  ? 105 GLN F OE1 1 
ATOM   4007 N NE2 . GLN C 3 109 ? 8.665   -37.418 -22.884 1.00 49.95  ? 105 GLN F NE2 1 
ATOM   4008 N N   . GLY C 3 110 ? 5.783   -35.444 -25.012 1.00 30.02  ? 106 GLY F N   1 
ATOM   4009 C CA  . GLY C 3 110 ? 4.596   -34.969 -24.334 1.00 29.22  ? 106 GLY F CA  1 
ATOM   4010 C C   . GLY C 3 110 ? 4.336   -35.697 -23.024 1.00 32.78  ? 106 GLY F C   1 
ATOM   4011 O O   . GLY C 3 110 ? 4.786   -36.823 -22.795 1.00 32.75  ? 106 GLY F O   1 
ATOM   4012 N N   . THR C 3 111 ? 3.591   -35.025 -22.146 1.00 28.52  ? 107 THR F N   1 
ATOM   4013 C CA  . THR C 3 111 ? 3.153   -35.589 -20.877 1.00 30.74  ? 107 THR F CA  1 
ATOM   4014 C C   . THR C 3 111 ? 1.659   -35.340 -20.718 1.00 28.65  ? 107 THR F C   1 
ATOM   4015 O O   . THR C 3 111 ? 1.151   -34.282 -21.103 1.00 28.63  ? 107 THR F O   1 
ATOM   4016 C CB  . THR C 3 111 ? 3.940   -34.993 -19.690 1.00 31.95  ? 107 THR F CB  1 
ATOM   4017 O OG1 . THR C 3 111 ? 3.516   -35.611 -18.468 1.00 43.55  ? 107 THR F OG1 1 
ATOM   4018 C CG2 . THR C 3 111 ? 3.740   -33.484 -19.593 1.00 29.30  ? 107 THR F CG2 1 
ATOM   4019 N N   . LEU C 3 112 ? 0.955   -36.323 -20.163 1.00 30.69  ? 108 LEU F N   1 
ATOM   4020 C CA  . LEU C 3 112 ? -0.500  -36.282 -20.081 1.00 26.80  ? 108 LEU F CA  1 
ATOM   4021 C C   . LEU C 3 112 ? -0.942  -35.690 -18.749 1.00 28.84  ? 108 LEU F C   1 
ATOM   4022 O O   . LEU C 3 112 ? -0.517  -36.149 -17.684 1.00 35.97  ? 108 LEU F O   1 
ATOM   4023 C CB  . LEU C 3 112 ? -1.087  -37.683 -20.254 1.00 27.10  ? 108 LEU F CB  1 
ATOM   4024 C CG  . LEU C 3 112 ? -2.601  -37.805 -20.072 1.00 30.96  ? 108 LEU F CG  1 
ATOM   4025 C CD1 . LEU C 3 112 ? -3.335  -36.959 -21.101 1.00 22.81  ? 108 LEU F CD1 1 
ATOM   4026 C CD2 . LEU C 3 112 ? -3.031  -39.259 -20.159 1.00 36.03  ? 108 LEU F CD2 1 
ATOM   4027 N N   . VAL C 3 113 ? -1.802  -34.678 -18.815 1.00 26.39  ? 109 VAL F N   1 
ATOM   4028 C CA  . VAL C 3 113 ? -2.353  -34.025 -17.636 1.00 23.80  ? 109 VAL F CA  1 
ATOM   4029 C C   . VAL C 3 113 ? -3.856  -34.260 -17.647 1.00 30.46  ? 109 VAL F C   1 
ATOM   4030 O O   . VAL C 3 113 ? -4.560  -33.783 -18.547 1.00 34.86  ? 109 VAL F O   1 
ATOM   4031 C CB  . VAL C 3 113 ? -2.028  -32.524 -17.604 1.00 17.62  ? 109 VAL F CB  1 
ATOM   4032 C CG1 . VAL C 3 113 ? -2.777  -31.840 -16.472 1.00 20.83  ? 109 VAL F CG1 1 
ATOM   4033 C CG2 . VAL C 3 113 ? -0.529  -32.316 -17.461 1.00 25.69  ? 109 VAL F CG2 1 
ATOM   4034 N N   . THR C 3 114 ? -4.348  -34.994 -16.654 1.00 32.12  ? 110 THR F N   1 
ATOM   4035 C CA  . THR C 3 114 ? -5.768  -35.281 -16.507 1.00 25.95  ? 110 THR F CA  1 
ATOM   4036 C C   . THR C 3 114 ? -6.289  -34.541 -15.283 1.00 32.43  ? 110 THR F C   1 
ATOM   4037 O O   . THR C 3 114 ? -5.818  -34.776 -14.165 1.00 37.28  ? 110 THR F O   1 
ATOM   4038 C CB  . THR C 3 114 ? -6.018  -36.783 -16.369 1.00 28.71  ? 110 THR F CB  1 
ATOM   4039 O OG1 . THR C 3 114 ? -5.547  -37.460 -17.541 1.00 33.41  ? 110 THR F OG1 1 
ATOM   4040 C CG2 . THR C 3 114 ? -7.503  -37.059 -16.191 1.00 25.99  ? 110 THR F CG2 1 
ATOM   4041 N N   . VAL C 3 115 ? -7.252  -33.652 -15.495 1.00 27.02  ? 111 VAL F N   1 
ATOM   4042 C CA  . VAL C 3 115 ? -7.878  -32.897 -14.417 1.00 37.09  ? 111 VAL F CA  1 
ATOM   4043 C C   . VAL C 3 115 ? -9.277  -33.464 -14.224 1.00 42.91  ? 111 VAL F C   1 
ATOM   4044 O O   . VAL C 3 115 ? -10.140 -33.328 -15.100 1.00 44.25  ? 111 VAL F O   1 
ATOM   4045 C CB  . VAL C 3 115 ? -7.920  -31.394 -14.717 1.00 30.26  ? 111 VAL F CB  1 
ATOM   4046 C CG1 . VAL C 3 115 ? -8.405  -30.625 -13.496 1.00 36.96  ? 111 VAL F CG1 1 
ATOM   4047 C CG2 . VAL C 3 115 ? -6.551  -30.902 -15.159 1.00 24.81  ? 111 VAL F CG2 1 
ATOM   4048 N N   . SER C 3 116 ? -9.503  -34.097 -13.076 1.00 39.86  ? 112 SER F N   1 
ATOM   4049 C CA  . SER C 3 116 ? -10.778 -34.739 -12.796 1.00 43.71  ? 112 SER F CA  1 
ATOM   4050 C C   . SER C 3 116 ? -10.906 -34.948 -11.295 1.00 47.49  ? 112 SER F C   1 
ATOM   4051 O O   . SER C 3 116 ? -9.905  -35.062 -10.584 1.00 36.15  ? 112 SER F O   1 
ATOM   4052 C CB  . SER C 3 116 ? -10.904 -36.077 -13.534 1.00 38.00  ? 112 SER F CB  1 
ATOM   4053 O OG  . SER C 3 116 ? -12.089 -36.758 -13.162 1.00 46.76  ? 112 SER F OG  1 
ATOM   4054 N N   . SER C 3 117 ? -12.151 -34.992 -10.825 1.00 54.32  ? 113 SER F N   1 
ATOM   4055 C CA  . SER C 3 117 ? -12.433 -35.308 -9.433  1.00 50.68  ? 113 SER F CA  1 
ATOM   4056 C C   . SER C 3 117 ? -12.551 -36.805 -9.183  1.00 41.74  ? 113 SER F C   1 
ATOM   4057 O O   . SER C 3 117 ? -12.657 -37.218 -8.024  1.00 56.82  ? 113 SER F O   1 
ATOM   4058 C CB  . SER C 3 117 ? -13.721 -34.611 -8.979  1.00 47.21  ? 113 SER F CB  1 
ATOM   4059 O OG  . SER C 3 117 ? -14.838 -35.076 -9.716  1.00 57.68  ? 113 SER F OG  1 
ATOM   4060 N N   . ALA C 3 118 ? -12.532 -37.620 -10.235 1.00 46.18  ? 114 ALA F N   1 
ATOM   4061 C CA  . ALA C 3 118 ? -12.604 -39.063 -10.073 1.00 43.22  ? 114 ALA F CA  1 
ATOM   4062 C C   . ALA C 3 118 ? -11.325 -39.598 -9.439  1.00 44.60  ? 114 ALA F C   1 
ATOM   4063 O O   . ALA C 3 118 ? -10.251 -39.002 -9.549  1.00 43.38  ? 114 ALA F O   1 
ATOM   4064 C CB  . ALA C 3 118 ? -12.843 -39.742 -11.421 1.00 39.35  ? 114 ALA F CB  1 
ATOM   4065 N N   . SER C 3 119 ? -11.451 -40.739 -8.772  1.00 59.64  ? 115 SER F N   1 
ATOM   4066 C CA  . SER C 3 119 ? -10.337 -41.344 -8.060  1.00 50.15  ? 115 SER F CA  1 
ATOM   4067 C C   . SER C 3 119 ? -9.598  -42.336 -8.951  1.00 41.51  ? 115 SER F C   1 
ATOM   4068 O O   . SER C 3 119 ? -10.151 -42.890 -9.903  1.00 45.34  ? 115 SER F O   1 
ATOM   4069 C CB  . SER C 3 119 ? -10.826 -42.044 -6.792  1.00 40.97  ? 115 SER F CB  1 
ATOM   4070 O OG  . SER C 3 119 ? -11.461 -41.128 -5.918  1.00 65.42  ? 115 SER F OG  1 
ATOM   4071 N N   . THR C 3 120 ? -8.324  -42.545 -8.630  1.00 31.03  ? 116 THR F N   1 
ATOM   4072 C CA  . THR C 3 120 ? -7.526  -43.541 -9.329  1.00 30.54  ? 116 THR F CA  1 
ATOM   4073 C C   . THR C 3 120 ? -8.009  -44.943 -8.978  1.00 36.25  ? 116 THR F C   1 
ATOM   4074 O O   . THR C 3 120 ? -8.318  -45.239 -7.821  1.00 47.16  ? 116 THR F O   1 
ATOM   4075 C CB  . THR C 3 120 ? -6.049  -43.388 -8.963  1.00 27.29  ? 116 THR F CB  1 
ATOM   4076 O OG1 . THR C 3 120 ? -5.632  -42.038 -9.200  1.00 38.53  ? 116 THR F OG1 1 
ATOM   4077 C CG2 . THR C 3 120 ? -5.187  -44.328 -9.792  1.00 30.93  ? 116 THR F CG2 1 
ATOM   4078 N N   . LYS C 3 121 ? -8.084  -45.807 -9.987  1.00 35.47  ? 117 LYS F N   1 
ATOM   4079 C CA  . LYS C 3 121 ? -8.457  -47.199 -9.780  1.00 36.19  ? 117 LYS F CA  1 
ATOM   4080 C C   . LYS C 3 121 ? -7.597  -48.082 -10.667 1.00 38.07  ? 117 LYS F C   1 
ATOM   4081 O O   . LYS C 3 121 ? -7.405  -47.780 -11.848 1.00 40.40  ? 117 LYS F O   1 
ATOM   4082 C CB  . LYS C 3 121 ? -9.942  -47.436 -10.081 1.00 45.72  ? 117 LYS F CB  1 
ATOM   4083 C CG  . LYS C 3 121 ? -10.377 -48.882 -9.898  1.00 42.46  ? 117 LYS F CG  1 
ATOM   4084 C CD  . LYS C 3 121 ? -11.829 -49.090 -10.288 1.00 42.95  ? 117 LYS F CD  1 
ATOM   4085 C CE  . LYS C 3 121 ? -12.226 -50.552 -10.148 1.00 43.79  ? 117 LYS F CE  1 
ATOM   4086 N NZ  . LYS C 3 121 ? -11.375 -51.442 -10.989 1.00 45.38  ? 117 LYS F NZ  1 
ATOM   4087 N N   . GLY C 3 122 ? -7.080  -49.166 -10.095 1.00 48.61  ? 118 GLY F N   1 
ATOM   4088 C CA  . GLY C 3 122 ? -6.307  -50.126 -10.845 1.00 41.44  ? 118 GLY F CA  1 
ATOM   4089 C C   . GLY C 3 122 ? -7.178  -50.963 -11.759 1.00 46.49  ? 118 GLY F C   1 
ATOM   4090 O O   . GLY C 3 122 ? -8.366  -51.181 -11.497 1.00 50.17  ? 118 GLY F O   1 
ATOM   4091 N N   . PRO C 3 123 ? -6.604  -51.450 -12.853 1.00 48.50  ? 119 PRO F N   1 
ATOM   4092 C CA  . PRO C 3 123 ? -7.375  -52.261 -13.797 1.00 43.73  ? 119 PRO F CA  1 
ATOM   4093 C C   . PRO C 3 123 ? -7.515  -53.703 -13.334 1.00 50.72  ? 119 PRO F C   1 
ATOM   4094 O O   . PRO C 3 123 ? -6.771  -54.196 -12.484 1.00 64.67  ? 119 PRO F O   1 
ATOM   4095 C CB  . PRO C 3 123 ? -6.545  -52.181 -15.081 1.00 50.18  ? 119 PRO F CB  1 
ATOM   4096 C CG  . PRO C 3 123 ? -5.146  -52.035 -14.590 1.00 38.86  ? 119 PRO F CG  1 
ATOM   4097 C CD  . PRO C 3 123 ? -5.228  -51.212 -13.325 1.00 49.18  ? 119 PRO F CD  1 
ATOM   4098 N N   . SER C 3 124 ? -8.497  -54.378 -13.922 1.00 52.20  ? 120 SER F N   1 
ATOM   4099 C CA  . SER C 3 124 ? -8.691  -55.810 -13.752 1.00 38.97  ? 120 SER F CA  1 
ATOM   4100 C C   . SER C 3 124 ? -8.373  -56.497 -15.072 1.00 50.09  ? 120 SER F C   1 
ATOM   4101 O O   . SER C 3 124 ? -8.924  -56.127 -16.115 1.00 58.36  ? 120 SER F O   1 
ATOM   4102 C CB  . SER C 3 124 ? -10.122 -56.126 -13.312 1.00 40.02  ? 120 SER F CB  1 
ATOM   4103 O OG  . SER C 3 124 ? -10.448 -55.446 -12.113 1.00 44.94  ? 120 SER F OG  1 
ATOM   4104 N N   . VAL C 3 125 ? -7.486  -57.485 -15.028 1.00 43.93  ? 121 VAL F N   1 
ATOM   4105 C CA  . VAL C 3 125 ? -6.997  -58.156 -16.226 1.00 38.53  ? 121 VAL F CA  1 
ATOM   4106 C C   . VAL C 3 125 ? -7.661  -59.520 -16.331 1.00 39.78  ? 121 VAL F C   1 
ATOM   4107 O O   . VAL C 3 125 ? -7.612  -60.317 -15.386 1.00 40.75  ? 121 VAL F O   1 
ATOM   4108 C CB  . VAL C 3 125 ? -5.465  -58.288 -16.204 1.00 45.84  ? 121 VAL F CB  1 
ATOM   4109 C CG1 . VAL C 3 125 ? -4.965  -58.889 -17.507 1.00 48.14  ? 121 VAL F CG1 1 
ATOM   4110 C CG2 . VAL C 3 125 ? -4.822  -56.932 -15.952 1.00 48.14  ? 121 VAL F CG2 1 
ATOM   4111 N N   . PHE C 3 126 ? -8.279  -59.788 -17.477 1.00 40.68  ? 122 PHE F N   1 
ATOM   4112 C CA  . PHE C 3 126 ? -8.946  -61.053 -17.732 1.00 38.59  ? 122 PHE F CA  1 
ATOM   4113 C C   . PHE C 3 126 ? -8.465  -61.634 -19.052 1.00 46.98  ? 122 PHE F C   1 
ATOM   4114 O O   . PHE C 3 126 ? -8.151  -60.889 -19.987 1.00 44.55  ? 122 PHE F O   1 
ATOM   4115 C CB  . PHE C 3 126 ? -10.471 -60.882 -17.772 1.00 40.32  ? 122 PHE F CB  1 
ATOM   4116 C CG  . PHE C 3 126 ? -11.045 -60.271 -16.527 1.00 41.85  ? 122 PHE F CG  1 
ATOM   4117 C CD1 . PHE C 3 126 ? -11.035 -60.968 -15.331 1.00 40.55  ? 122 PHE F CD1 1 
ATOM   4118 C CD2 . PHE C 3 126 ? -11.599 -59.003 -16.554 1.00 47.51  ? 122 PHE F CD2 1 
ATOM   4119 C CE1 . PHE C 3 126 ? -11.561 -60.408 -14.183 1.00 44.79  ? 122 PHE F CE1 1 
ATOM   4120 C CE2 . PHE C 3 126 ? -12.129 -58.439 -15.409 1.00 50.61  ? 122 PHE F CE2 1 
ATOM   4121 C CZ  . PHE C 3 126 ? -12.111 -59.143 -14.222 1.00 43.01  ? 122 PHE F CZ  1 
ATOM   4122 N N   . PRO C 3 127 ? -8.395  -62.957 -19.155 1.00 42.67  ? 123 PRO F N   1 
ATOM   4123 C CA  . PRO C 3 127 ? -7.929  -63.582 -20.395 1.00 50.66  ? 123 PRO F CA  1 
ATOM   4124 C C   . PRO C 3 127 ? -9.023  -63.657 -21.451 1.00 63.07  ? 123 PRO F C   1 
ATOM   4125 O O   . PRO C 3 127 ? -10.221 -63.636 -21.160 1.00 60.73  ? 123 PRO F O   1 
ATOM   4126 C CB  . PRO C 3 127 ? -7.512  -64.984 -19.941 1.00 62.78  ? 123 PRO F CB  1 
ATOM   4127 C CG  . PRO C 3 127 ? -8.413  -65.268 -18.788 1.00 50.27  ? 123 PRO F CG  1 
ATOM   4128 C CD  . PRO C 3 127 ? -8.618  -63.947 -18.087 1.00 54.55  ? 123 PRO F CD  1 
ATOM   4129 N N   . LEU C 3 128 ? -8.579  -63.746 -22.702 1.00 62.24  ? 124 LEU F N   1 
ATOM   4130 C CA  . LEU C 3 128 ? -9.443  -63.991 -23.855 1.00 52.62  ? 124 LEU F CA  1 
ATOM   4131 C C   . LEU C 3 128 ? -8.993  -65.323 -24.450 1.00 64.32  ? 124 LEU F C   1 
ATOM   4132 O O   . LEU C 3 128 ? -8.143  -65.362 -25.342 1.00 67.14  ? 124 LEU F O   1 
ATOM   4133 C CB  . LEU C 3 128 ? -9.364  -62.853 -24.871 1.00 46.88  ? 124 LEU F CB  1 
ATOM   4134 C CG  . LEU C 3 128 ? -9.703  -61.457 -24.343 1.00 53.21  ? 124 LEU F CG  1 
ATOM   4135 C CD1 . LEU C 3 128 ? -9.610  -60.419 -25.453 1.00 42.28  ? 124 LEU F CD1 1 
ATOM   4136 C CD2 . LEU C 3 128 ? -11.085 -61.444 -23.705 1.00 41.70  ? 124 LEU F CD2 1 
ATOM   4137 N N   . ALA C 3 129 ? -9.567  -66.411 -23.944 1.00 73.92  ? 125 ALA F N   1 
ATOM   4138 C CA  . ALA C 3 129 ? -9.099  -67.742 -24.300 1.00 71.77  ? 125 ALA F CA  1 
ATOM   4139 C C   . ALA C 3 129 ? -9.374  -68.038 -25.772 1.00 74.21  ? 125 ALA F C   1 
ATOM   4140 O O   . ALA C 3 129 ? -10.438 -67.687 -26.291 1.00 72.56  ? 125 ALA F O   1 
ATOM   4141 C CB  . ALA C 3 129 ? -9.770  -68.797 -23.422 1.00 69.10  ? 125 ALA F CB  1 
ATOM   4142 N N   . PRO C 3 130 ? -8.438  -68.675 -26.469 1.00 91.11  ? 126 PRO F N   1 
ATOM   4143 C CA  . PRO C 3 130 ? -8.676  -69.070 -27.859 1.00 88.76  ? 126 PRO F CA  1 
ATOM   4144 C C   . PRO C 3 130 ? -9.498  -70.350 -27.940 1.00 83.29  ? 126 PRO F C   1 
ATOM   4145 O O   . PRO C 3 130 ? -9.729  -71.045 -26.950 1.00 78.79  ? 126 PRO F O   1 
ATOM   4146 C CB  . PRO C 3 130 ? -7.262  -69.287 -28.405 1.00 77.36  ? 126 PRO F CB  1 
ATOM   4147 C CG  . PRO C 3 130 ? -6.480  -69.722 -27.212 1.00 83.27  ? 126 PRO F CG  1 
ATOM   4148 C CD  . PRO C 3 130 ? -7.063  -68.978 -26.034 1.00 88.27  ? 126 PRO F CD  1 
ATOM   4149 N N   . SER C 3 131 ? -9.940  -70.653 -29.159 1.00 87.77  ? 127 SER F N   1 
ATOM   4150 C CA  . SER C 3 131 ? -10.696 -71.865 -29.433 1.00 87.12  ? 127 SER F CA  1 
ATOM   4151 C C   . SER C 3 131 ? -10.176 -72.499 -30.714 1.00 90.32  ? 127 SER F C   1 
ATOM   4152 O O   . SER C 3 131 ? -9.640  -71.815 -31.591 1.00 86.47  ? 127 SER F O   1 
ATOM   4153 C CB  . SER C 3 131 ? -12.199 -71.581 -29.557 1.00 83.76  ? 127 SER F CB  1 
ATOM   4154 O OG  . SER C 3 131 ? -12.464 -70.692 -30.629 1.00 71.73  ? 127 SER F OG  1 
ATOM   4155 N N   . SER C 3 132 ? -10.338 -73.814 -30.813 1.00 87.08  ? 128 SER F N   1 
ATOM   4156 C CA  . SER C 3 132 ? -9.885  -74.555 -31.984 1.00 81.64  ? 128 SER F CA  1 
ATOM   4157 C C   . SER C 3 132 ? -11.007 -74.704 -33.006 1.00 76.27  ? 128 SER F C   1 
ATOM   4158 O O   . SER C 3 132 ? -11.428 -73.728 -33.627 1.00 72.21  ? 128 SER F O   1 
ATOM   4159 C CB  . SER C 3 132 ? -9.356  -75.932 -31.578 1.00 75.25  ? 128 SER F CB  1 
ATOM   4160 O OG  . SER C 3 132 ? -8.252  -75.814 -30.696 1.00 67.60  ? 128 SER F OG  1 
ATOM   4161 N N   . THR C 3 139 ? -4.744  -70.716 -37.983 1.00 85.61  ? 135 THR F N   1 
ATOM   4162 C CA  . THR C 3 139 ? -4.572  -69.394 -37.391 1.00 84.47  ? 135 THR F CA  1 
ATOM   4163 C C   . THR C 3 139 ? -5.561  -69.166 -36.253 1.00 92.89  ? 135 THR F C   1 
ATOM   4164 O O   . THR C 3 139 ? -6.773  -69.122 -36.470 1.00 100.31 ? 135 THR F O   1 
ATOM   4165 C CB  . THR C 3 139 ? -4.745  -68.279 -38.439 1.00 78.42  ? 135 THR F CB  1 
ATOM   4166 O OG1 . THR C 3 139 ? -3.722  -68.392 -39.436 1.00 76.78  ? 135 THR F OG1 1 
ATOM   4167 C CG2 . THR C 3 139 ? -4.658  -66.911 -37.781 1.00 76.64  ? 135 THR F CG2 1 
ATOM   4168 N N   . ALA C 3 140 ? -5.036  -69.021 -35.042 1.00 81.86  ? 136 ALA F N   1 
ATOM   4169 C CA  . ALA C 3 140 ? -5.834  -68.766 -33.853 1.00 81.20  ? 136 ALA F CA  1 
ATOM   4170 C C   . ALA C 3 140 ? -5.577  -67.352 -33.346 1.00 82.58  ? 136 ALA F C   1 
ATOM   4171 O O   . ALA C 3 140 ? -4.637  -66.673 -33.767 1.00 83.53  ? 136 ALA F O   1 
ATOM   4172 C CB  . ALA C 3 140 ? -5.527  -69.795 -32.758 1.00 76.07  ? 136 ALA F CB  1 
ATOM   4173 N N   . ALA C 3 141 ? -6.437  -66.909 -32.430 1.00 79.15  ? 137 ALA F N   1 
ATOM   4174 C CA  . ALA C 3 141 ? -6.327  -65.582 -31.846 1.00 65.87  ? 137 ALA F CA  1 
ATOM   4175 C C   . ALA C 3 141 ? -6.609  -65.656 -30.353 1.00 62.55  ? 137 ALA F C   1 
ATOM   4176 O O   . ALA C 3 141 ? -7.400  -66.485 -29.895 1.00 68.65  ? 137 ALA F O   1 
ATOM   4177 C CB  . ALA C 3 141 ? -7.288  -64.590 -32.518 1.00 61.82  ? 137 ALA F CB  1 
ATOM   4178 N N   . LEU C 3 142 ? -5.956  -64.774 -29.600 1.00 53.11  ? 138 LEU F N   1 
ATOM   4179 C CA  . LEU C 3 142 ? -6.137  -64.684 -28.157 1.00 55.34  ? 138 LEU F CA  1 
ATOM   4180 C C   . LEU C 3 142 ? -5.761  -63.276 -27.721 1.00 58.48  ? 138 LEU F C   1 
ATOM   4181 O O   . LEU C 3 142 ? -5.122  -62.527 -28.463 1.00 61.68  ? 138 LEU F O   1 
ATOM   4182 C CB  . LEU C 3 142 ? -5.293  -65.724 -27.411 1.00 62.67  ? 138 LEU F CB  1 
ATOM   4183 C CG  . LEU C 3 142 ? -3.771  -65.522 -27.439 1.00 63.13  ? 138 LEU F CG  1 
ATOM   4184 C CD1 . LEU C 3 142 ? -3.248  -64.681 -26.258 1.00 73.12  ? 138 LEU F CD1 1 
ATOM   4185 C CD2 . LEU C 3 142 ? -3.050  -66.862 -27.521 1.00 66.02  ? 138 LEU F CD2 1 
ATOM   4186 N N   . GLY C 3 143 ? -6.136  -62.936 -26.495 1.00 55.28  ? 139 GLY F N   1 
ATOM   4187 C CA  . GLY C 3 143 ? -5.813  -61.621 -25.986 1.00 46.32  ? 139 GLY F CA  1 
ATOM   4188 C C   . GLY C 3 143 ? -6.077  -61.508 -24.501 1.00 56.06  ? 139 GLY F C   1 
ATOM   4189 O O   . GLY C 3 143 ? -6.344  -62.497 -23.817 1.00 52.34  ? 139 GLY F O   1 
ATOM   4190 N N   . CYS C 3 144 ? -5.983  -60.272 -24.012 1.00 50.89  ? 140 CYS F N   1 
ATOM   4191 C CA  . CYS C 3 144 ? -6.259  -59.942 -22.622 1.00 48.47  ? 140 CYS F CA  1 
ATOM   4192 C C   . CYS C 3 144 ? -7.201  -58.748 -22.562 1.00 45.28  ? 140 CYS F C   1 
ATOM   4193 O O   . CYS C 3 144 ? -7.140  -57.846 -23.402 1.00 44.35  ? 140 CYS F O   1 
ATOM   4194 C CB  . CYS C 3 144 ? -4.970  -59.631 -21.841 1.00 53.24  ? 140 CYS F CB  1 
ATOM   4195 S SG  . CYS C 3 144 ? -4.108  -61.097 -21.228 1.00 106.57 ? 140 CYS F SG  1 
ATOM   4196 N N   . LEU C 3 145 ? -8.074  -58.754 -21.560 1.00 43.73  ? 141 LEU F N   1 
ATOM   4197 C CA  . LEU C 3 145 ? -9.044  -57.687 -21.349 1.00 36.21  ? 141 LEU F CA  1 
ATOM   4198 C C   . LEU C 3 145 ? -8.627  -56.877 -20.130 1.00 39.77  ? 141 LEU F C   1 
ATOM   4199 O O   . LEU C 3 145 ? -8.489  -57.427 -19.032 1.00 39.01  ? 141 LEU F O   1 
ATOM   4200 C CB  . LEU C 3 145 ? -10.452 -58.252 -21.162 1.00 42.96  ? 141 LEU F CB  1 
ATOM   4201 C CG  . LEU C 3 145 ? -11.555 -57.231 -20.874 1.00 45.73  ? 141 LEU F CG  1 
ATOM   4202 C CD1 . LEU C 3 145 ? -11.786 -56.325 -22.075 1.00 28.89  ? 141 LEU F CD1 1 
ATOM   4203 C CD2 . LEU C 3 145 ? -12.841 -57.932 -20.468 1.00 29.59  ? 141 LEU F CD2 1 
ATOM   4204 N N   . VAL C 3 146 ? -8.434  -55.578 -20.325 1.00 37.36  ? 142 VAL F N   1 
ATOM   4205 C CA  . VAL C 3 146 ? -8.039  -54.659 -19.265 1.00 42.25  ? 142 VAL F CA  1 
ATOM   4206 C C   . VAL C 3 146 ? -9.225  -53.739 -19.015 1.00 41.21  ? 142 VAL F C   1 
ATOM   4207 O O   . VAL C 3 146 ? -9.585  -52.930 -19.880 1.00 49.38  ? 142 VAL F O   1 
ATOM   4208 C CB  . VAL C 3 146 ? -6.780  -53.868 -19.644 1.00 45.98  ? 142 VAL F CB  1 
ATOM   4209 C CG1 . VAL C 3 146 ? -6.150  -53.249 -18.414 1.00 47.97  ? 142 VAL F CG1 1 
ATOM   4210 C CG2 . VAL C 3 146 ? -5.788  -54.769 -20.365 1.00 34.17  ? 142 VAL F CG2 1 
ATOM   4211 N N   . LYS C 3 147 ? -9.834  -53.847 -17.836 1.00 35.87  ? 143 LYS F N   1 
ATOM   4212 C CA  . LYS C 3 147 ? -11.114 -53.205 -17.584 1.00 38.03  ? 143 LYS F CA  1 
ATOM   4213 C C   . LYS C 3 147 ? -11.089 -52.416 -16.282 1.00 40.42  ? 143 LYS F C   1 
ATOM   4214 O O   . LYS C 3 147 ? -10.396 -52.775 -15.326 1.00 43.33  ? 143 LYS F O   1 
ATOM   4215 C CB  . LYS C 3 147 ? -12.254 -54.236 -17.533 1.00 36.87  ? 143 LYS F CB  1 
ATOM   4216 C CG  . LYS C 3 147 ? -13.610 -53.645 -17.865 1.00 45.07  ? 143 LYS F CG  1 
ATOM   4217 C CD  . LYS C 3 147 ? -14.752 -54.420 -17.241 1.00 42.01  ? 143 LYS F CD  1 
ATOM   4218 C CE  . LYS C 3 147 ? -16.033 -53.602 -17.302 1.00 55.75  ? 143 LYS F CE  1 
ATOM   4219 N NZ  . LYS C 3 147 ? -17.175 -54.262 -16.617 1.00 60.68  ? 143 LYS F NZ  1 
ATOM   4220 N N   . ASP C 3 148 ? -11.864 -51.328 -16.269 1.00 37.69  ? 144 ASP F N   1 
ATOM   4221 C CA  . ASP C 3 148 ? -12.162 -50.548 -15.068 1.00 44.39  ? 144 ASP F CA  1 
ATOM   4222 C C   . ASP C 3 148 ? -10.895 -49.980 -14.423 1.00 46.84  ? 144 ASP F C   1 
ATOM   4223 O O   . ASP C 3 148 ? -10.531 -50.316 -13.294 1.00 51.70  ? 144 ASP F O   1 
ATOM   4224 C CB  . ASP C 3 148 ? -12.964 -51.386 -14.066 1.00 48.93  ? 144 ASP F CB  1 
ATOM   4225 C CG  . ASP C 3 148 ? -14.305 -51.828 -14.620 1.00 55.08  ? 144 ASP F CG  1 
ATOM   4226 O OD1 . ASP C 3 148 ? -14.897 -51.073 -15.421 1.00 47.14  ? 144 ASP F OD1 1 
ATOM   4227 O OD2 . ASP C 3 148 ? -14.767 -52.931 -14.257 1.00 61.32  ? 144 ASP F OD2 1 
ATOM   4228 N N   . TYR C 3 149 ? -10.227 -49.098 -15.164 1.00 43.35  ? 145 TYR F N   1 
ATOM   4229 C CA  . TYR C 3 149 ? -9.089  -48.355 -14.646 1.00 37.40  ? 145 TYR F CA  1 
ATOM   4230 C C   . TYR C 3 149 ? -9.276  -46.871 -14.931 1.00 42.05  ? 145 TYR F C   1 
ATOM   4231 O O   . TYR C 3 149 ? -10.000 -46.479 -15.849 1.00 38.98  ? 145 TYR F O   1 
ATOM   4232 C CB  . TYR C 3 149 ? -7.758  -48.842 -15.241 1.00 35.90  ? 145 TYR F CB  1 
ATOM   4233 C CG  . TYR C 3 149 ? -7.591  -48.589 -16.724 1.00 37.60  ? 145 TYR F CG  1 
ATOM   4234 C CD1 . TYR C 3 149 ? -7.087  -47.382 -17.192 1.00 32.31  ? 145 TYR F CD1 1 
ATOM   4235 C CD2 . TYR C 3 149 ? -7.918  -49.566 -17.655 1.00 34.51  ? 145 TYR F CD2 1 
ATOM   4236 C CE1 . TYR C 3 149 ? -6.930  -47.148 -18.543 1.00 31.95  ? 145 TYR F CE1 1 
ATOM   4237 C CE2 . TYR C 3 149 ? -7.761  -49.342 -19.009 1.00 32.17  ? 145 TYR F CE2 1 
ATOM   4238 C CZ  . TYR C 3 149 ? -7.266  -48.133 -19.447 1.00 36.37  ? 145 TYR F CZ  1 
ATOM   4239 O OH  . TYR C 3 149 ? -7.108  -47.907 -20.794 1.00 45.89  ? 145 TYR F OH  1 
ATOM   4240 N N   . PHE C 3 150 ? -8.604  -46.045 -14.124 1.00 39.54  ? 146 PHE F N   1 
ATOM   4241 C CA  . PHE C 3 150 ? -8.638  -44.602 -14.301 1.00 31.52  ? 146 PHE F CA  1 
ATOM   4242 C C   . PHE C 3 150 ? -7.444  -44.004 -13.581 1.00 42.02  ? 146 PHE F C   1 
ATOM   4243 O O   . PHE C 3 150 ? -7.132  -44.442 -12.465 1.00 45.57  ? 146 PHE F O   1 
ATOM   4244 C CB  . PHE C 3 150 ? -9.939  -43.999 -13.759 1.00 30.95  ? 146 PHE F CB  1 
ATOM   4245 C CG  . PHE C 3 150 ? -10.069 -42.520 -13.997 1.00 34.05  ? 146 PHE F CG  1 
ATOM   4246 C CD1 . PHE C 3 150 ? -10.598 -42.041 -15.184 1.00 39.07  ? 146 PHE F CD1 1 
ATOM   4247 C CD2 . PHE C 3 150 ? -9.665  -41.610 -13.034 1.00 34.10  ? 146 PHE F CD2 1 
ATOM   4248 C CE1 . PHE C 3 150 ? -10.719 -40.681 -15.408 1.00 33.02  ? 146 PHE F CE1 1 
ATOM   4249 C CE2 . PHE C 3 150 ? -9.783  -40.250 -13.252 1.00 40.69  ? 146 PHE F CE2 1 
ATOM   4250 C CZ  . PHE C 3 150 ? -10.312 -39.785 -14.441 1.00 30.48  ? 146 PHE F CZ  1 
ATOM   4251 N N   . PRO C 3 151 ? -6.752  -43.025 -14.173 1.00 46.31  ? 147 PRO F N   1 
ATOM   4252 C CA  . PRO C 3 151 ? -6.942  -42.486 -15.523 1.00 38.16  ? 147 PRO F CA  1 
ATOM   4253 C C   . PRO C 3 151 ? -6.026  -43.156 -16.544 1.00 39.70  ? 147 PRO F C   1 
ATOM   4254 O O   . PRO C 3 151 ? -5.419  -44.186 -16.266 1.00 36.16  ? 147 PRO F O   1 
ATOM   4255 C CB  . PRO C 3 151 ? -6.606  -41.005 -15.335 1.00 40.18  ? 147 PRO F CB  1 
ATOM   4256 C CG  . PRO C 3 151 ? -5.492  -41.036 -14.318 1.00 42.21  ? 147 PRO F CG  1 
ATOM   4257 C CD  . PRO C 3 151 ? -5.810  -42.199 -13.394 1.00 39.91  ? 147 PRO F CD  1 
ATOM   4258 N N   . GLU C 3 152 ? -5.919  -42.579 -17.738 1.00 45.76  ? 148 GLU F N   1 
ATOM   4259 C CA  . GLU C 3 152 ? -4.989  -43.067 -18.740 1.00 39.00  ? 148 GLU F CA  1 
ATOM   4260 C C   . GLU C 3 152 ? -3.550  -42.823 -18.284 1.00 39.77  ? 148 GLU F C   1 
ATOM   4261 O O   . GLU C 3 152 ? -3.295  -41.953 -17.449 1.00 39.94  ? 148 GLU F O   1 
ATOM   4262 C CB  . GLU C 3 152 ? -5.248  -42.375 -20.077 1.00 49.85  ? 148 GLU F CB  1 
ATOM   4263 C CG  . GLU C 3 152 ? -6.498  -42.846 -20.808 1.00 50.51  ? 148 GLU F CG  1 
ATOM   4264 C CD  . GLU C 3 152 ? -6.265  -44.106 -21.624 1.00 50.45  ? 148 GLU F CD  1 
ATOM   4265 O OE1 . GLU C 3 152 ? -5.773  -45.107 -21.062 1.00 49.88  ? 148 GLU F OE1 1 
ATOM   4266 O OE2 . GLU C 3 152 ? -6.566  -44.091 -22.836 1.00 51.87  ? 148 GLU F OE2 1 
ATOM   4267 N N   . PRO C 3 153 ? -2.580  -43.582 -18.824 1.00 47.39  ? 149 PRO F N   1 
ATOM   4268 C CA  . PRO C 3 153 ? -2.683  -44.665 -19.806 1.00 42.95  ? 149 PRO F CA  1 
ATOM   4269 C C   . PRO C 3 153 ? -2.404  -46.052 -19.231 1.00 40.73  ? 149 PRO F C   1 
ATOM   4270 O O   . PRO C 3 153 ? -2.111  -46.206 -18.049 1.00 48.69  ? 149 PRO F O   1 
ATOM   4271 C CB  . PRO C 3 153 ? -1.616  -44.266 -20.831 1.00 39.82  ? 149 PRO F CB  1 
ATOM   4272 C CG  . PRO C 3 153 ? -0.548  -43.519 -20.004 1.00 48.31  ? 149 PRO F CG  1 
ATOM   4273 C CD  . PRO C 3 153 ? -1.172  -43.195 -18.653 1.00 41.06  ? 149 PRO F CD  1 
ATOM   4274 N N   . VAL C 3 154 ? -2.499  -47.083 -20.067 1.00 40.60  ? 150 VAL F N   1 
ATOM   4275 C CA  . VAL C 3 154 ? -2.148  -48.449 -19.698 1.00 41.73  ? 150 VAL F CA  1 
ATOM   4276 C C   . VAL C 3 154 ? -1.283  -49.036 -20.805 1.00 53.89  ? 150 VAL F C   1 
ATOM   4277 O O   . VAL C 3 154 ? -1.623  -48.926 -21.988 1.00 53.32  ? 150 VAL F O   1 
ATOM   4278 C CB  . VAL C 3 154 ? -3.398  -49.319 -19.463 1.00 40.13  ? 150 VAL F CB  1 
ATOM   4279 C CG1 . VAL C 3 154 ? -3.046  -50.796 -19.541 1.00 49.18  ? 150 VAL F CG1 1 
ATOM   4280 C CG2 . VAL C 3 154 ? -4.013  -48.999 -18.114 1.00 41.87  ? 150 VAL F CG2 1 
ATOM   4281 N N   . THR C 3 155 ? -0.169  -49.654 -20.421 1.00 57.71  ? 151 THR F N   1 
ATOM   4282 C CA  . THR C 3 155 ? 0.743   -50.299 -21.354 1.00 53.88  ? 151 THR F CA  1 
ATOM   4283 C C   . THR C 3 155 ? 0.605   -51.811 -21.241 1.00 55.44  ? 151 THR F C   1 
ATOM   4284 O O   . THR C 3 155 ? 0.553   -52.357 -20.134 1.00 60.68  ? 151 THR F O   1 
ATOM   4285 C CB  . THR C 3 155 ? 2.193   -49.889 -21.085 1.00 57.16  ? 151 THR F CB  1 
ATOM   4286 O OG1 . THR C 3 155 ? 2.575   -50.316 -19.771 1.00 55.97  ? 151 THR F OG1 1 
ATOM   4287 C CG2 . THR C 3 155 ? 2.346   -48.379 -21.186 1.00 39.99  ? 151 THR F CG2 1 
ATOM   4288 N N   . VAL C 3 156 ? 0.541   -52.484 -22.388 1.00 58.14  ? 152 VAL F N   1 
ATOM   4289 C CA  . VAL C 3 156 ? 0.361   -53.929 -22.446 1.00 67.17  ? 152 VAL F CA  1 
ATOM   4290 C C   . VAL C 3 156 ? 1.468   -54.529 -23.302 1.00 72.96  ? 152 VAL F C   1 
ATOM   4291 O O   . VAL C 3 156 ? 1.748   -54.034 -24.400 1.00 69.97  ? 152 VAL F O   1 
ATOM   4292 C CB  . VAL C 3 156 ? -1.021  -54.315 -23.007 1.00 56.55  ? 152 VAL F CB  1 
ATOM   4293 C CG1 . VAL C 3 156 ? -1.180  -55.828 -23.028 1.00 50.61  ? 152 VAL F CG1 1 
ATOM   4294 C CG2 . VAL C 3 156 ? -2.128  -53.671 -22.187 1.00 53.41  ? 152 VAL F CG2 1 
ATOM   4295 N N   . SER C 3 157 ? 2.095   -55.591 -22.798 1.00 66.01  ? 153 SER F N   1 
ATOM   4296 C CA  . SER C 3 157 ? 3.104   -56.334 -23.536 1.00 72.59  ? 153 SER F CA  1 
ATOM   4297 C C   . SER C 3 157 ? 2.867   -57.823 -23.326 1.00 76.46  ? 153 SER F C   1 
ATOM   4298 O O   . SER C 3 157 ? 2.201   -58.236 -22.374 1.00 73.64  ? 153 SER F O   1 
ATOM   4299 C CB  . SER C 3 157 ? 4.526   -55.952 -23.103 1.00 87.44  ? 153 SER F CB  1 
ATOM   4300 O OG  . SER C 3 157 ? 4.770   -56.329 -21.760 1.00 74.70  ? 153 SER F OG  1 
ATOM   4301 N N   . TRP C 3 158 ? 3.418   -58.629 -24.230 1.00 79.13  ? 154 TRP F N   1 
ATOM   4302 C CA  . TRP C 3 158 ? 3.212   -60.071 -24.227 1.00 80.59  ? 154 TRP F CA  1 
ATOM   4303 C C   . TRP C 3 158 ? 4.545   -60.789 -24.080 1.00 83.64  ? 154 TRP F C   1 
ATOM   4304 O O   . TRP C 3 158 ? 5.468   -60.557 -24.869 1.00 84.88  ? 154 TRP F O   1 
ATOM   4305 C CB  . TRP C 3 158 ? 2.502   -60.523 -25.505 1.00 83.99  ? 154 TRP F CB  1 
ATOM   4306 C CG  . TRP C 3 158 ? 1.085   -60.056 -25.575 1.00 81.60  ? 154 TRP F CG  1 
ATOM   4307 C CD1 . TRP C 3 158 ? 0.636   -58.865 -26.066 1.00 73.11  ? 154 TRP F CD1 1 
ATOM   4308 C CD2 . TRP C 3 158 ? -0.073  -60.768 -25.127 1.00 75.32  ? 154 TRP F CD2 1 
ATOM   4309 N NE1 . TRP C 3 158 ? -0.732  -58.794 -25.956 1.00 69.41  ? 154 TRP F NE1 1 
ATOM   4310 C CE2 . TRP C 3 158 ? -1.191  -59.950 -25.383 1.00 70.99  ? 154 TRP F CE2 1 
ATOM   4311 C CE3 . TRP C 3 158 ? -0.273  -62.020 -24.538 1.00 74.56  ? 154 TRP F CE3 1 
ATOM   4312 C CZ2 . TRP C 3 158 ? -2.489  -60.343 -25.069 1.00 64.15  ? 154 TRP F CZ2 1 
ATOM   4313 C CZ3 . TRP C 3 158 ? -1.561  -62.407 -24.227 1.00 77.09  ? 154 TRP F CZ3 1 
ATOM   4314 C CH2 . TRP C 3 158 ? -2.652  -61.572 -24.493 1.00 70.38  ? 154 TRP F CH2 1 
ATOM   4315 N N   . ASN C 3 159 ? 4.631   -61.670 -23.082 1.00 91.20  ? 155 ASN F N   1 
ATOM   4316 C CA  . ASN C 3 159 ? 5.843   -62.430 -22.777 1.00 82.65  ? 155 ASN F CA  1 
ATOM   4317 C C   . ASN C 3 159 ? 7.050   -61.498 -22.669 1.00 88.91  ? 155 ASN F C   1 
ATOM   4318 O O   . ASN C 3 159 ? 8.028   -61.607 -23.411 1.00 83.32  ? 155 ASN F O   1 
ATOM   4319 C CB  . ASN C 3 159 ? 6.079   -63.525 -23.822 1.00 78.09  ? 155 ASN F CB  1 
ATOM   4320 C CG  . ASN C 3 159 ? 4.969   -64.557 -23.846 1.00 74.76  ? 155 ASN F CG  1 
ATOM   4321 O OD1 . ASN C 3 159 ? 4.349   -64.843 -22.821 1.00 83.61  ? 155 ASN F OD1 1 
ATOM   4322 N ND2 . ASN C 3 159 ? 4.711   -65.122 -25.020 1.00 74.61  ? 155 ASN F ND2 1 
ATOM   4323 N N   . SER C 3 160 ? 6.957   -60.573 -21.715 1.00 89.07  ? 156 SER F N   1 
ATOM   4324 C CA  . SER C 3 160 ? 7.896   -59.450 -21.588 1.00 88.96  ? 156 SER F CA  1 
ATOM   4325 C C   . SER C 3 160 ? 7.839   -58.701 -22.918 1.00 85.23  ? 156 SER F C   1 
ATOM   4326 O O   . SER C 3 160 ? 6.741   -58.306 -23.341 1.00 96.58  ? 156 SER F O   1 
ATOM   4327 C CB  . SER C 3 160 ? 9.273   -59.951 -21.164 1.00 93.42  ? 156 SER F CB  1 
ATOM   4328 O OG  . SER C 3 160 ? 9.211   -60.634 -19.924 1.00 102.60 ? 156 SER F OG  1 
ATOM   4329 N N   . GLY C 3 161 ? 8.957   -58.488 -23.603 1.00 76.04  ? 157 GLY F N   1 
ATOM   4330 C CA  . GLY C 3 161 ? 8.959   -57.890 -24.921 1.00 81.86  ? 157 GLY F CA  1 
ATOM   4331 C C   . GLY C 3 161 ? 9.157   -58.861 -26.065 1.00 88.09  ? 157 GLY F C   1 
ATOM   4332 O O   . GLY C 3 161 ? 9.438   -58.420 -27.186 1.00 85.69  ? 157 GLY F O   1 
ATOM   4333 N N   . ALA C 3 162 ? 9.021   -60.167 -25.823 1.00 89.13  ? 158 ALA F N   1 
ATOM   4334 C CA  . ALA C 3 162 ? 9.319   -61.155 -26.858 1.00 93.22  ? 158 ALA F CA  1 
ATOM   4335 C C   . ALA C 3 162 ? 8.326   -61.077 -28.011 1.00 93.62  ? 158 ALA F C   1 
ATOM   4336 O O   . ALA C 3 162 ? 8.723   -61.013 -29.181 1.00 98.75  ? 158 ALA F O   1 
ATOM   4337 C CB  . ALA C 3 162 ? 9.330   -62.559 -26.253 1.00 81.95  ? 158 ALA F CB  1 
ATOM   4338 N N   . LEU C 3 163 ? 7.030   -61.081 -27.706 1.00 92.39  ? 159 LEU F N   1 
ATOM   4339 C CA  . LEU C 3 163 ? 5.992   -61.115 -28.731 1.00 88.65  ? 159 LEU F CA  1 
ATOM   4340 C C   . LEU C 3 163 ? 5.636   -59.686 -29.125 1.00 93.21  ? 159 LEU F C   1 
ATOM   4341 O O   . LEU C 3 163 ? 5.047   -58.942 -28.333 1.00 84.11  ? 159 LEU F O   1 
ATOM   4342 C CB  . LEU C 3 163 ? 4.766   -61.876 -28.233 1.00 82.21  ? 159 LEU F CB  1 
ATOM   4343 C CG  . LEU C 3 163 ? 3.647   -62.088 -29.255 1.00 85.24  ? 159 LEU F CG  1 
ATOM   4344 C CD1 . LEU C 3 163 ? 4.204   -62.669 -30.546 1.00 76.16  ? 159 LEU F CD1 1 
ATOM   4345 C CD2 . LEU C 3 163 ? 2.566   -62.991 -28.684 1.00 93.83  ? 159 LEU F CD2 1 
ATOM   4346 N N   . THR C 3 164 ? 5.992   -59.304 -30.350 1.00 94.51  ? 160 THR F N   1 
ATOM   4347 C CA  . THR C 3 164 ? 5.708   -57.976 -30.874 1.00 85.10  ? 160 THR F CA  1 
ATOM   4348 C C   . THR C 3 164 ? 4.896   -57.987 -32.160 1.00 92.96  ? 160 THR F C   1 
ATOM   4349 O O   . THR C 3 164 ? 4.074   -57.089 -32.358 1.00 86.15  ? 160 THR F O   1 
ATOM   4350 C CB  . THR C 3 164 ? 7.014   -57.205 -31.126 1.00 98.22  ? 160 THR F CB  1 
ATOM   4351 O OG1 . THR C 3 164 ? 7.822   -57.922 -32.068 1.00 103.55 ? 160 THR F OG1 1 
ATOM   4352 C CG2 . THR C 3 164 ? 7.790   -57.029 -29.829 1.00 91.07  ? 160 THR F CG2 1 
ATOM   4353 N N   . SER C 3 165 ? 5.103   -58.967 -33.036 1.00 97.42  ? 161 SER F N   1 
ATOM   4354 C CA  . SER C 3 165 ? 4.338   -59.057 -34.272 1.00 90.30  ? 161 SER F CA  1 
ATOM   4355 C C   . SER C 3 165 ? 2.955   -59.625 -33.982 1.00 85.53  ? 161 SER F C   1 
ATOM   4356 O O   . SER C 3 165 ? 2.819   -60.608 -33.246 1.00 83.57  ? 161 SER F O   1 
ATOM   4357 C CB  . SER C 3 165 ? 5.071   -59.928 -35.292 1.00 88.95  ? 161 SER F CB  1 
ATOM   4358 O OG  . SER C 3 165 ? 4.363   -59.983 -36.519 1.00 78.02  ? 161 SER F OG  1 
ATOM   4359 N N   . GLY C 3 166 ? 1.930   -59.006 -34.563 1.00 81.53  ? 162 GLY F N   1 
ATOM   4360 C CA  . GLY C 3 166 ? 0.560   -59.399 -34.316 1.00 78.57  ? 162 GLY F CA  1 
ATOM   4361 C C   . GLY C 3 166 ? -0.073  -58.778 -33.090 1.00 78.26  ? 162 GLY F C   1 
ATOM   4362 O O   . GLY C 3 166 ? -1.246  -59.058 -32.812 1.00 76.03  ? 162 GLY F O   1 
ATOM   4363 N N   . VAL C 3 167 ? 0.657   -57.948 -32.353 1.00 82.22  ? 163 VAL F N   1 
ATOM   4364 C CA  . VAL C 3 167 ? 0.118   -57.293 -31.166 1.00 72.87  ? 163 VAL F CA  1 
ATOM   4365 C C   . VAL C 3 167 ? -0.775  -56.139 -31.606 1.00 75.28  ? 163 VAL F C   1 
ATOM   4366 O O   . VAL C 3 167 ? -0.337  -55.243 -32.336 1.00 70.49  ? 163 VAL F O   1 
ATOM   4367 C CB  . VAL C 3 167 ? 1.245   -56.800 -30.246 1.00 77.03  ? 163 VAL F CB  1 
ATOM   4368 C CG1 . VAL C 3 167 ? 0.724   -55.744 -29.282 1.00 73.42  ? 163 VAL F CG1 1 
ATOM   4369 C CG2 . VAL C 3 167 ? 1.850   -57.966 -29.479 1.00 83.38  ? 163 VAL F CG2 1 
ATOM   4370 N N   . HIS C 3 168 ? -2.032  -56.164 -31.166 1.00 69.00  ? 164 HIS F N   1 
ATOM   4371 C CA  . HIS C 3 168 ? -2.991  -55.097 -31.440 1.00 58.31  ? 164 HIS F CA  1 
ATOM   4372 C C   . HIS C 3 168 ? -3.585  -54.651 -30.108 1.00 53.31  ? 164 HIS F C   1 
ATOM   4373 O O   . HIS C 3 168 ? -4.429  -55.345 -29.535 1.00 55.17  ? 164 HIS F O   1 
ATOM   4374 C CB  . HIS C 3 168 ? -4.081  -55.558 -32.405 1.00 54.57  ? 164 HIS F CB  1 
ATOM   4375 C CG  . HIS C 3 168 ? -3.607  -55.735 -33.814 1.00 63.72  ? 164 HIS F CG  1 
ATOM   4376 N ND1 . HIS C 3 168 ? -3.082  -54.700 -34.558 1.00 63.75  ? 164 HIS F ND1 1 
ATOM   4377 C CD2 . HIS C 3 168 ? -3.588  -56.824 -34.619 1.00 68.80  ? 164 HIS F CD2 1 
ATOM   4378 C CE1 . HIS C 3 168 ? -2.755  -55.146 -35.758 1.00 67.38  ? 164 HIS F CE1 1 
ATOM   4379 N NE2 . HIS C 3 168 ? -3.052  -56.431 -35.821 1.00 73.53  ? 164 HIS F NE2 1 
ATOM   4380 N N   . THR C 3 169 ? -3.144  -53.495 -29.617 1.00 60.50  ? 165 THR F N   1 
ATOM   4381 C CA  . THR C 3 169 ? -3.680  -52.900 -28.397 1.00 55.29  ? 165 THR F CA  1 
ATOM   4382 C C   . THR C 3 169 ? -4.629  -51.777 -28.801 1.00 47.55  ? 165 THR F C   1 
ATOM   4383 O O   . THR C 3 169 ? -4.191  -50.718 -29.262 1.00 46.99  ? 165 THR F O   1 
ATOM   4384 C CB  . THR C 3 169 ? -2.560  -52.383 -27.497 1.00 55.71  ? 165 THR F CB  1 
ATOM   4385 O OG1 . THR C 3 169 ? -1.762  -53.485 -27.046 1.00 59.00  ? 165 THR F OG1 1 
ATOM   4386 C CG2 . THR C 3 169 ? -3.140  -51.659 -26.291 1.00 53.23  ? 165 THR F CG2 1 
ATOM   4387 N N   . PHE C 3 170 ? -5.926  -52.017 -28.635 1.00 43.18  ? 166 PHE F N   1 
ATOM   4388 C CA  . PHE C 3 170 ? -6.929  -51.070 -29.089 1.00 43.58  ? 166 PHE F CA  1 
ATOM   4389 C C   . PHE C 3 170 ? -6.935  -49.820 -28.209 1.00 41.35  ? 166 PHE F C   1 
ATOM   4390 O O   . PHE C 3 170 ? -6.592  -49.882 -27.025 1.00 41.31  ? 166 PHE F O   1 
ATOM   4391 C CB  . PHE C 3 170 ? -8.312  -51.715 -29.080 1.00 35.08  ? 166 PHE F CB  1 
ATOM   4392 C CG  . PHE C 3 170 ? -8.441  -52.879 -30.019 1.00 35.73  ? 166 PHE F CG  1 
ATOM   4393 C CD1 . PHE C 3 170 ? -8.062  -54.151 -29.623 1.00 35.90  ? 166 PHE F CD1 1 
ATOM   4394 C CD2 . PHE C 3 170 ? -8.941  -52.702 -31.297 1.00 33.07  ? 166 PHE F CD2 1 
ATOM   4395 C CE1 . PHE C 3 170 ? -8.177  -55.223 -30.485 1.00 40.76  ? 166 PHE F CE1 1 
ATOM   4396 C CE2 . PHE C 3 170 ? -9.058  -53.770 -32.163 1.00 38.12  ? 166 PHE F CE2 1 
ATOM   4397 C CZ  . PHE C 3 170 ? -8.676  -55.032 -31.756 1.00 48.32  ? 166 PHE F CZ  1 
ATOM   4398 N N   . PRO C 3 171 ? -7.309  -48.670 -28.771 1.00 44.93  ? 167 PRO F N   1 
ATOM   4399 C CA  . PRO C 3 171 ? -7.479  -47.470 -27.946 1.00 39.42  ? 167 PRO F CA  1 
ATOM   4400 C C   . PRO C 3 171 ? -8.540  -47.680 -26.877 1.00 48.49  ? 167 PRO F C   1 
ATOM   4401 O O   . PRO C 3 171 ? -9.535  -48.378 -27.084 1.00 42.16  ? 167 PRO F O   1 
ATOM   4402 C CB  . PRO C 3 171 ? -7.908  -46.401 -28.958 1.00 25.91  ? 167 PRO F CB  1 
ATOM   4403 C CG  . PRO C 3 171 ? -7.379  -46.890 -30.267 1.00 37.38  ? 167 PRO F CG  1 
ATOM   4404 C CD  . PRO C 3 171 ? -7.474  -48.386 -30.207 1.00 35.10  ? 167 PRO F CD  1 
ATOM   4405 N N   . ALA C 3 172 ? -8.309  -47.070 -25.718 1.00 50.31  ? 168 ALA F N   1 
ATOM   4406 C CA  . ALA C 3 172 ? -9.227  -47.221 -24.599 1.00 37.51  ? 168 ALA F CA  1 
ATOM   4407 C C   . ALA C 3 172 ? -10.553 -46.527 -24.884 1.00 41.63  ? 168 ALA F C   1 
ATOM   4408 O O   . ALA C 3 172 ? -10.597 -45.469 -25.518 1.00 43.33  ? 168 ALA F O   1 
ATOM   4409 C CB  . ALA C 3 172 ? -8.605  -46.654 -23.324 1.00 40.80  ? 168 ALA F CB  1 
ATOM   4410 N N   . VAL C 3 173 ? -11.639 -47.134 -24.412 1.00 32.23  ? 169 VAL F N   1 
ATOM   4411 C CA  . VAL C 3 173 ? -12.972 -46.552 -24.497 1.00 44.33  ? 169 VAL F CA  1 
ATOM   4412 C C   . VAL C 3 173 ? -13.384 -46.105 -23.102 1.00 40.02  ? 169 VAL F C   1 
ATOM   4413 O O   . VAL C 3 173 ? -13.038 -46.747 -22.102 1.00 37.33  ? 169 VAL F O   1 
ATOM   4414 C CB  . VAL C 3 173 ? -13.999 -47.539 -25.093 1.00 41.93  ? 169 VAL F CB  1 
ATOM   4415 C CG1 . VAL C 3 173 ? -13.462 -48.152 -26.378 1.00 34.61  ? 169 VAL F CG1 1 
ATOM   4416 C CG2 . VAL C 3 173 ? -14.371 -48.626 -24.093 1.00 44.78  ? 169 VAL F CG2 1 
ATOM   4417 N N   . LEU C 3 174 ? -14.092 -44.983 -23.032 1.00 44.02  ? 170 LEU F N   1 
ATOM   4418 C CA  . LEU C 3 174 ? -14.592 -44.464 -21.766 1.00 32.07  ? 170 LEU F CA  1 
ATOM   4419 C C   . LEU C 3 174 ? -15.996 -45.012 -21.544 1.00 43.35  ? 170 LEU F C   1 
ATOM   4420 O O   . LEU C 3 174 ? -16.920 -44.699 -22.303 1.00 54.60  ? 170 LEU F O   1 
ATOM   4421 C CB  . LEU C 3 174 ? -14.585 -42.936 -21.765 1.00 33.23  ? 170 LEU F CB  1 
ATOM   4422 C CG  . LEU C 3 174 ? -15.154 -42.272 -20.510 1.00 39.81  ? 170 LEU F CG  1 
ATOM   4423 C CD1 . LEU C 3 174 ? -14.424 -42.753 -19.266 1.00 35.28  ? 170 LEU F CD1 1 
ATOM   4424 C CD2 . LEU C 3 174 ? -15.085 -40.755 -20.620 1.00 16.49  ? 170 LEU F CD2 1 
ATOM   4425 N N   . GLN C 3 175 ? -16.154 -45.829 -20.508 1.00 46.29  ? 171 GLN F N   1 
ATOM   4426 C CA  . GLN C 3 175 ? -17.441 -46.428 -20.206 1.00 42.41  ? 171 GLN F CA  1 
ATOM   4427 C C   . GLN C 3 175 ? -18.365 -45.409 -19.549 1.00 39.19  ? 171 GLN F C   1 
ATOM   4428 O O   . GLN C 3 175 ? -17.938 -44.348 -19.085 1.00 36.10  ? 171 GLN F O   1 
ATOM   4429 C CB  . GLN C 3 175 ? -17.269 -47.639 -19.292 1.00 40.85  ? 171 GLN F CB  1 
ATOM   4430 C CG  . GLN C 3 175 ? -16.434 -48.750 -19.892 1.00 39.12  ? 171 GLN F CG  1 
ATOM   4431 C CD  . GLN C 3 175 ? -15.979 -49.752 -18.856 1.00 55.62  ? 171 GLN F CD  1 
ATOM   4432 O OE1 . GLN C 3 175 ? -15.988 -50.959 -19.098 1.00 58.30  ? 171 GLN F OE1 1 
ATOM   4433 N NE2 . GLN C 3 175 ? -15.566 -49.258 -17.695 1.00 49.71  ? 171 GLN F NE2 1 
ATOM   4434 N N   . SER C 3 176 ? -19.655 -45.750 -19.515 1.00 48.17  ? 172 SER F N   1 
ATOM   4435 C CA  . SER C 3 176 ? -20.631 -44.904 -18.840 1.00 53.65  ? 172 SER F CA  1 
ATOM   4436 C C   . SER C 3 176 ? -20.368 -44.807 -17.343 1.00 50.71  ? 172 SER F C   1 
ATOM   4437 O O   . SER C 3 176 ? -20.861 -43.876 -16.696 1.00 55.90  ? 172 SER F O   1 
ATOM   4438 C CB  . SER C 3 176 ? -22.044 -45.432 -19.098 1.00 47.00  ? 172 SER F CB  1 
ATOM   4439 O OG  . SER C 3 176 ? -22.080 -46.847 -19.027 1.00 66.38  ? 172 SER F OG  1 
ATOM   4440 N N   . SER C 3 177 ? -19.600 -45.741 -16.781 1.00 39.02  ? 173 SER F N   1 
ATOM   4441 C CA  . SER C 3 177 ? -19.218 -45.690 -15.377 1.00 39.02  ? 173 SER F CA  1 
ATOM   4442 C C   . SER C 3 177 ? -18.099 -44.694 -15.105 1.00 50.39  ? 173 SER F C   1 
ATOM   4443 O O   . SER C 3 177 ? -17.758 -44.475 -13.937 1.00 45.06  ? 173 SER F O   1 
ATOM   4444 C CB  . SER C 3 177 ? -18.793 -47.081 -14.898 1.00 45.03  ? 173 SER F CB  1 
ATOM   4445 O OG  . SER C 3 177 ? -17.664 -47.547 -15.618 1.00 38.64  ? 173 SER F OG  1 
ATOM   4446 N N   . GLY C 3 178 ? -17.526 -44.088 -16.143 1.00 48.24  ? 174 GLY F N   1 
ATOM   4447 C CA  . GLY C 3 178 ? -16.421 -43.167 -15.986 1.00 40.92  ? 174 GLY F CA  1 
ATOM   4448 C C   . GLY C 3 178 ? -15.051 -43.805 -15.977 1.00 38.08  ? 174 GLY F C   1 
ATOM   4449 O O   . GLY C 3 178 ? -14.055 -43.093 -15.797 1.00 37.19  ? 174 GLY F O   1 
ATOM   4450 N N   . LEU C 3 179 ? -14.965 -45.117 -16.166 1.00 45.30  ? 175 LEU F N   1 
ATOM   4451 C CA  . LEU C 3 179 ? -13.702 -45.835 -16.195 1.00 33.47  ? 175 LEU F CA  1 
ATOM   4452 C C   . LEU C 3 179 ? -13.376 -46.256 -17.622 1.00 39.00  ? 175 LEU F C   1 
ATOM   4453 O O   . LEU C 3 179 ? -14.251 -46.333 -18.488 1.00 39.94  ? 175 LEU F O   1 
ATOM   4454 C CB  . LEU C 3 179 ? -13.748 -47.063 -15.279 1.00 42.75  ? 175 LEU F CB  1 
ATOM   4455 C CG  . LEU C 3 179 ? -14.112 -46.791 -13.817 1.00 45.73  ? 175 LEU F CG  1 
ATOM   4456 C CD1 . LEU C 3 179 ? -14.195 -48.089 -13.032 1.00 40.84  ? 175 LEU F CD1 1 
ATOM   4457 C CD2 . LEU C 3 179 ? -13.111 -45.839 -13.179 1.00 40.32  ? 175 LEU F CD2 1 
ATOM   4458 N N   . TYR C 3 180 ? -12.098 -46.529 -17.857 1.00 33.78  ? 176 TYR F N   1 
ATOM   4459 C CA  . TYR C 3 180 ? -11.613 -46.904 -19.175 1.00 30.22  ? 176 TYR F CA  1 
ATOM   4460 C C   . TYR C 3 180 ? -11.473 -48.416 -19.287 1.00 33.52  ? 176 TYR F C   1 
ATOM   4461 O O   . TYR C 3 180 ? -11.192 -49.110 -18.307 1.00 37.42  ? 176 TYR F O   1 
ATOM   4462 C CB  . TYR C 3 180 ? -10.267 -46.238 -19.473 1.00 31.85  ? 176 TYR F CB  1 
ATOM   4463 C CG  . TYR C 3 180 ? -10.347 -44.740 -19.648 1.00 33.54  ? 176 TYR F CG  1 
ATOM   4464 C CD1 . TYR C 3 180 ? -10.223 -43.887 -18.559 1.00 38.89  ? 176 TYR F CD1 1 
ATOM   4465 C CD2 . TYR C 3 180 ? -10.545 -44.177 -20.902 1.00 32.64  ? 176 TYR F CD2 1 
ATOM   4466 C CE1 . TYR C 3 180 ? -10.295 -42.516 -18.714 1.00 41.58  ? 176 TYR F CE1 1 
ATOM   4467 C CE2 . TYR C 3 180 ? -10.618 -42.808 -21.067 1.00 24.46  ? 176 TYR F CE2 1 
ATOM   4468 C CZ  . TYR C 3 180 ? -10.492 -41.982 -19.970 1.00 36.86  ? 176 TYR F CZ  1 
ATOM   4469 O OH  . TYR C 3 180 ? -10.565 -40.617 -20.129 1.00 43.44  ? 176 TYR F OH  1 
ATOM   4470 N N   . SER C 3 181 ? -11.677 -48.920 -20.501 1.00 32.09  ? 177 SER F N   1 
ATOM   4471 C CA  . SER C 3 181 ? -11.492 -50.329 -20.812 1.00 33.92  ? 177 SER F CA  1 
ATOM   4472 C C   . SER C 3 181 ? -10.666 -50.459 -22.081 1.00 41.22  ? 177 SER F C   1 
ATOM   4473 O O   . SER C 3 181 ? -10.747 -49.621 -22.983 1.00 42.85  ? 177 SER F O   1 
ATOM   4474 C CB  . SER C 3 181 ? -12.830 -51.054 -20.982 1.00 45.00  ? 177 SER F CB  1 
ATOM   4475 O OG  . SER C 3 181 ? -13.524 -51.121 -19.751 1.00 58.03  ? 177 SER F OG  1 
ATOM   4476 N N   . LEU C 3 182 ? -9.875  -51.526 -22.146 1.00 42.30  ? 178 LEU F N   1 
ATOM   4477 C CA  . LEU C 3 182 ? -8.929  -51.715 -23.233 1.00 36.40  ? 178 LEU F CA  1 
ATOM   4478 C C   . LEU C 3 182 ? -8.703  -53.205 -23.441 1.00 41.80  ? 178 LEU F C   1 
ATOM   4479 O O   . LEU C 3 182 ? -8.780  -53.997 -22.497 1.00 43.48  ? 178 LEU F O   1 
ATOM   4480 C CB  . LEU C 3 182 ? -7.608  -50.987 -22.935 1.00 45.79  ? 178 LEU F CB  1 
ATOM   4481 C CG  . LEU C 3 182 ? -6.338  -51.265 -23.744 1.00 44.83  ? 178 LEU F CG  1 
ATOM   4482 C CD1 . LEU C 3 182 ? -5.529  -49.991 -23.893 1.00 55.70  ? 178 LEU F CD1 1 
ATOM   4483 C CD2 . LEU C 3 182 ? -5.496  -52.336 -23.070 1.00 42.73  ? 178 LEU F CD2 1 
ATOM   4484 N N   . SER C 3 183 ? -8.430  -53.581 -24.689 1.00 45.51  ? 179 SER F N   1 
ATOM   4485 C CA  . SER C 3 183 ? -8.107  -54.955 -25.039 1.00 43.47  ? 179 SER F CA  1 
ATOM   4486 C C   . SER C 3 183 ? -6.852  -54.989 -25.896 1.00 44.46  ? 179 SER F C   1 
ATOM   4487 O O   . SER C 3 183 ? -6.604  -54.090 -26.704 1.00 51.84  ? 179 SER F O   1 
ATOM   4488 C CB  . SER C 3 183 ? -9.258  -55.641 -25.789 1.00 46.01  ? 179 SER F CB  1 
ATOM   4489 O OG  . SER C 3 183 ? -10.128 -56.307 -24.891 1.00 58.51  ? 179 SER F OG  1 
ATOM   4490 N N   . SER C 3 184 ? -6.058  -56.039 -25.703 1.00 45.21  ? 180 SER F N   1 
ATOM   4491 C CA  . SER C 3 184 ? -4.878  -56.299 -26.515 1.00 56.84  ? 180 SER F CA  1 
ATOM   4492 C C   . SER C 3 184 ? -4.930  -57.743 -26.984 1.00 47.99  ? 180 SER F C   1 
ATOM   4493 O O   . SER C 3 184 ? -5.035  -58.657 -26.162 1.00 50.26  ? 180 SER F O   1 
ATOM   4494 C CB  . SER C 3 184 ? -3.589  -56.037 -25.730 1.00 57.12  ? 180 SER F CB  1 
ATOM   4495 O OG  . SER C 3 184 ? -2.447  -56.257 -26.538 1.00 59.36  ? 180 SER F OG  1 
ATOM   4496 N N   . VAL C 3 185 ? -4.851  -57.948 -28.298 1.00 50.88  ? 181 VAL F N   1 
ATOM   4497 C CA  . VAL C 3 185 ? -4.995  -59.272 -28.884 1.00 61.78  ? 181 VAL F CA  1 
ATOM   4498 C C   . VAL C 3 185 ? -3.765  -59.576 -29.730 1.00 66.74  ? 181 VAL F C   1 
ATOM   4499 O O   . VAL C 3 185 ? -3.033  -58.680 -30.159 1.00 62.65  ? 181 VAL F O   1 
ATOM   4500 C CB  . VAL C 3 185 ? -6.280  -59.401 -29.730 1.00 63.23  ? 181 VAL F CB  1 
ATOM   4501 C CG1 . VAL C 3 185 ? -7.472  -58.808 -28.990 1.00 53.16  ? 181 VAL F CG1 1 
ATOM   4502 C CG2 . VAL C 3 185 ? -6.098  -58.739 -31.087 1.00 56.34  ? 181 VAL F CG2 1 
ATOM   4503 N N   . VAL C 3 186 ? -3.536  -60.872 -29.956 1.00 66.44  ? 182 VAL F N   1 
ATOM   4504 C CA  . VAL C 3 186 ? -2.419  -61.347 -30.762 1.00 72.80  ? 182 VAL F CA  1 
ATOM   4505 C C   . VAL C 3 186 ? -2.910  -62.435 -31.707 1.00 75.66  ? 182 VAL F C   1 
ATOM   4506 O O   . VAL C 3 186 ? -3.944  -63.069 -31.483 1.00 74.78  ? 182 VAL F O   1 
ATOM   4507 C CB  . VAL C 3 186 ? -1.256  -61.880 -29.896 1.00 72.86  ? 182 VAL F CB  1 
ATOM   4508 C CG1 . VAL C 3 186 ? -0.530  -60.734 -29.215 1.00 69.73  ? 182 VAL F CG1 1 
ATOM   4509 C CG2 . VAL C 3 186 ? -1.773  -62.863 -28.868 1.00 66.31  ? 182 VAL F CG2 1 
ATOM   4510 N N   . THR C 3 187 ? -2.147  -62.645 -32.776 1.00 77.17  ? 183 THR F N   1 
ATOM   4511 C CA  . THR C 3 187 ? -2.427  -63.675 -33.768 1.00 81.98  ? 183 THR F CA  1 
ATOM   4512 C C   . THR C 3 187 ? -1.340  -64.739 -33.674 1.00 86.04  ? 183 THR F C   1 
ATOM   4513 O O   . THR C 3 187 ? -0.151  -64.426 -33.800 1.00 78.78  ? 183 THR F O   1 
ATOM   4514 C CB  . THR C 3 187 ? -2.480  -63.082 -35.176 1.00 75.89  ? 183 THR F CB  1 
ATOM   4515 O OG1 . THR C 3 187 ? -3.044  -61.766 -35.120 1.00 69.33  ? 183 THR F OG1 1 
ATOM   4516 C CG2 . THR C 3 187 ? -3.335  -63.949 -36.083 1.00 81.59  ? 183 THR F CG2 1 
ATOM   4517 N N   . VAL C 3 188 ? -1.746  -65.988 -33.455 1.00 82.75  ? 184 VAL F N   1 
ATOM   4518 C CA  . VAL C 3 188 ? -0.785  -67.069 -33.223 1.00 77.75  ? 184 VAL F CA  1 
ATOM   4519 C C   . VAL C 3 188 ? -1.286  -68.341 -33.882 1.00 86.90  ? 184 VAL F C   1 
ATOM   4520 O O   . VAL C 3 188 ? -2.496  -68.570 -34.014 1.00 92.75  ? 184 VAL F O   1 
ATOM   4521 C CB  . VAL C 3 188 ? -0.552  -67.305 -31.709 1.00 80.16  ? 184 VAL F CB  1 
ATOM   4522 C CG1 . VAL C 3 188 ? -1.046  -68.677 -31.257 1.00 77.99  ? 184 VAL F CG1 1 
ATOM   4523 C CG2 . VAL C 3 188 ? 0.915   -67.101 -31.358 1.00 81.39  ? 184 VAL F CG2 1 
ATOM   4524 N N   . PRO C 3 189 ? -0.360  -69.185 -34.343 1.00 94.18  ? 185 PRO F N   1 
ATOM   4525 C CA  . PRO C 3 189 ? -0.765  -70.439 -34.989 1.00 88.60  ? 185 PRO F CA  1 
ATOM   4526 C C   . PRO C 3 189 ? -1.311  -71.450 -33.993 1.00 85.73  ? 185 PRO F C   1 
ATOM   4527 O O   . PRO C 3 189 ? -0.978  -71.438 -32.806 1.00 90.40  ? 185 PRO F O   1 
ATOM   4528 C CB  . PRO C 3 189 ? 0.534   -70.940 -35.630 1.00 94.11  ? 185 PRO F CB  1 
ATOM   4529 C CG  . PRO C 3 189 ? 1.612   -70.345 -34.791 1.00 85.72  ? 185 PRO F CG  1 
ATOM   4530 C CD  . PRO C 3 189 ? 1.100   -68.991 -34.388 1.00 85.39  ? 185 PRO F CD  1 
ATOM   4531 N N   . SER C 3 190 ? -2.156  -72.349 -34.503 1.00 87.96  ? 186 SER F N   1 
ATOM   4532 C CA  . SER C 3 190 ? -2.770  -73.378 -33.672 1.00 90.14  ? 186 SER F CA  1 
ATOM   4533 C C   . SER C 3 190 ? -1.779  -74.435 -33.203 1.00 98.08  ? 186 SER F C   1 
ATOM   4534 O O   . SER C 3 190 ? -2.106  -75.201 -32.290 1.00 93.18  ? 186 SER F O   1 
ATOM   4535 C CB  . SER C 3 190 ? -3.912  -74.054 -34.434 1.00 80.07  ? 186 SER F CB  1 
ATOM   4536 O OG  . SER C 3 190 ? -4.855  -73.103 -34.894 1.00 91.80  ? 186 SER F OG  1 
ATOM   4537 N N   . SER C 3 191 ? -0.588  -74.498 -33.803 1.00 100.43 ? 187 SER F N   1 
ATOM   4538 C CA  . SER C 3 191 ? 0.378   -75.531 -33.442 1.00 101.53 ? 187 SER F CA  1 
ATOM   4539 C C   . SER C 3 191 ? 0.870   -75.367 -32.008 1.00 108.14 ? 187 SER F C   1 
ATOM   4540 O O   . SER C 3 191 ? 1.065   -76.360 -31.297 1.00 108.52 ? 187 SER F O   1 
ATOM   4541 C CB  . SER C 3 191 ? 1.556   -75.508 -34.416 1.00 85.89  ? 187 SER F CB  1 
ATOM   4542 O OG  . SER C 3 191 ? 1.121   -75.708 -35.749 1.00 95.01  ? 187 SER F OG  1 
ATOM   4543 N N   . SER C 3 192 ? 1.081   -74.123 -31.569 1.00 105.32 ? 188 SER F N   1 
ATOM   4544 C CA  . SER C 3 192 ? 1.719   -73.886 -30.277 1.00 106.10 ? 188 SER F CA  1 
ATOM   4545 C C   . SER C 3 192 ? 0.864   -74.384 -29.116 1.00 110.29 ? 188 SER F C   1 
ATOM   4546 O O   . SER C 3 192 ? 1.381   -75.026 -28.194 1.00 112.84 ? 188 SER F O   1 
ATOM   4547 C CB  . SER C 3 192 ? 2.027   -72.398 -30.113 1.00 94.58  ? 188 SER F CB  1 
ATOM   4548 O OG  . SER C 3 192 ? 2.908   -71.941 -31.124 1.00 94.73  ? 188 SER F OG  1 
ATOM   4549 N N   . LEU C 3 193 ? -0.447  -74.126 -29.158 1.00 108.15 ? 189 LEU F N   1 
ATOM   4550 C CA  . LEU C 3 193 ? -1.356  -74.352 -28.034 1.00 112.15 ? 189 LEU F CA  1 
ATOM   4551 C C   . LEU C 3 193 ? -0.719  -73.956 -26.706 1.00 115.20 ? 189 LEU F C   1 
ATOM   4552 O O   . LEU C 3 193 ? -0.167  -72.858 -26.577 1.00 109.83 ? 189 LEU F O   1 
ATOM   4553 C CB  . LEU C 3 193 ? -1.838  -75.818 -27.982 1.00 107.45 ? 189 LEU F CB  1 
ATOM   4554 C CG  . LEU C 3 193 ? -1.000  -77.103 -28.159 1.00 102.15 ? 189 LEU F CG  1 
ATOM   4555 C CD1 . LEU C 3 193 ? -0.590  -77.760 -26.836 1.00 95.93  ? 189 LEU F CD1 1 
ATOM   4556 C CD2 . LEU C 3 193 ? -1.750  -78.116 -29.027 1.00 101.25 ? 189 LEU F CD2 1 
ATOM   4557 N N   . GLY C 3 194 ? -0.786  -74.848 -25.719 1.00 115.63 ? 190 GLY F N   1 
ATOM   4558 C CA  . GLY C 3 194 ? -0.136  -74.647 -24.439 1.00 106.04 ? 190 GLY F CA  1 
ATOM   4559 C C   . GLY C 3 194 ? 1.325   -75.040 -24.377 1.00 107.85 ? 190 GLY F C   1 
ATOM   4560 O O   . GLY C 3 194 ? 1.951   -74.858 -23.328 1.00 106.75 ? 190 GLY F O   1 
ATOM   4561 N N   . THR C 3 195 ? 1.887   -75.591 -25.459 1.00 109.48 ? 191 THR F N   1 
ATOM   4562 C CA  . THR C 3 195 ? 3.324   -75.857 -25.470 1.00 104.66 ? 191 THR F CA  1 
ATOM   4563 C C   . THR C 3 195 ? 4.110   -74.559 -25.356 1.00 105.55 ? 191 THR F C   1 
ATOM   4564 O O   . THR C 3 195 ? 5.125   -74.496 -24.653 1.00 98.30  ? 191 THR F O   1 
ATOM   4565 C CB  . THR C 3 195 ? 3.734   -76.617 -26.733 1.00 100.40 ? 191 THR F CB  1 
ATOM   4566 O OG1 . THR C 3 195 ? 3.432   -75.834 -27.895 1.00 103.57 ? 191 THR F OG1 1 
ATOM   4567 C CG2 . THR C 3 195 ? 3.021   -77.956 -26.819 1.00 95.78  ? 191 THR F CG2 1 
ATOM   4568 N N   . GLN C 3 196 ? 3.662   -73.516 -26.047 1.00 106.43 ? 192 GLN F N   1 
ATOM   4569 C CA  . GLN C 3 196 ? 4.219   -72.179 -25.906 1.00 100.00 ? 192 GLN F CA  1 
ATOM   4570 C C   . GLN C 3 196 ? 3.372   -71.399 -24.909 1.00 90.94  ? 192 GLN F C   1 
ATOM   4571 O O   . GLN C 3 196 ? 2.143   -71.349 -25.036 1.00 88.24  ? 192 GLN F O   1 
ATOM   4572 C CB  . GLN C 3 196 ? 4.255   -71.460 -27.257 1.00 92.20  ? 192 GLN F CB  1 
ATOM   4573 C CG  . GLN C 3 196 ? 5.589   -70.809 -27.591 1.00 90.89  ? 192 GLN F CG  1 
ATOM   4574 C CD  . GLN C 3 196 ? 5.881   -69.590 -26.738 1.00 93.49  ? 192 GLN F CD  1 
ATOM   4575 O OE1 . GLN C 3 196 ? 4.979   -69.008 -26.136 1.00 90.64  ? 192 GLN F OE1 1 
ATOM   4576 N NE2 . GLN C 3 196 ? 7.149   -69.198 -26.682 1.00 83.80  ? 192 GLN F NE2 1 
ATOM   4577 N N   . THR C 3 197 ? 4.026   -70.799 -23.918 1.00 84.18  ? 193 THR F N   1 
ATOM   4578 C CA  . THR C 3 197 ? 3.330   -70.087 -22.854 1.00 86.79  ? 193 THR F CA  1 
ATOM   4579 C C   . THR C 3 197 ? 3.198   -68.612 -23.212 1.00 89.62  ? 193 THR F C   1 
ATOM   4580 O O   . THR C 3 197 ? 4.186   -67.960 -23.565 1.00 85.95  ? 193 THR F O   1 
ATOM   4581 C CB  . THR C 3 197 ? 4.070   -70.252 -21.525 1.00 83.18  ? 193 THR F CB  1 
ATOM   4582 O OG1 . THR C 3 197 ? 3.742   -71.523 -20.949 1.00 85.34  ? 193 THR F OG1 1 
ATOM   4583 C CG2 . THR C 3 197 ? 3.693   -69.146 -20.550 1.00 81.20  ? 193 THR F CG2 1 
ATOM   4584 N N   . TYR C 3 198 ? 1.975   -68.094 -23.123 1.00 89.99  ? 194 TYR F N   1 
ATOM   4585 C CA  . TYR C 3 198 ? 1.676   -66.700 -23.424 1.00 86.92  ? 194 TYR F CA  1 
ATOM   4586 C C   . TYR C 3 198 ? 1.268   -65.978 -22.147 1.00 80.33  ? 194 TYR F C   1 
ATOM   4587 O O   . TYR C 3 198 ? 0.358   -66.423 -21.440 1.00 81.56  ? 194 TYR F O   1 
ATOM   4588 C CB  . TYR C 3 198 ? 0.562   -66.589 -24.467 1.00 79.65  ? 194 TYR F CB  1 
ATOM   4589 C CG  . TYR C 3 198 ? 0.852   -67.337 -25.746 1.00 85.51  ? 194 TYR F CG  1 
ATOM   4590 C CD1 . TYR C 3 198 ? 1.571   -66.742 -26.772 1.00 81.06  ? 194 TYR F CD1 1 
ATOM   4591 C CD2 . TYR C 3 198 ? 0.407   -68.640 -25.925 1.00 82.64  ? 194 TYR F CD2 1 
ATOM   4592 C CE1 . TYR C 3 198 ? 1.841   -67.423 -27.942 1.00 82.73  ? 194 TYR F CE1 1 
ATOM   4593 C CE2 . TYR C 3 198 ? 0.671   -69.330 -27.091 1.00 80.26  ? 194 TYR F CE2 1 
ATOM   4594 C CZ  . TYR C 3 198 ? 1.388   -68.716 -28.096 1.00 84.17  ? 194 TYR F CZ  1 
ATOM   4595 O OH  . TYR C 3 198 ? 1.654   -69.399 -29.259 1.00 87.58  ? 194 TYR F OH  1 
ATOM   4596 N N   . ILE C 3 199 ? 1.944   -64.869 -21.858 1.00 68.48  ? 195 ILE F N   1 
ATOM   4597 C CA  . ILE C 3 199 ? 1.644   -64.027 -20.707 1.00 74.92  ? 195 ILE F CA  1 
ATOM   4598 C C   . ILE C 3 199 ? 1.487   -62.597 -21.201 1.00 79.70  ? 195 ILE F C   1 
ATOM   4599 O O   . ILE C 3 199 ? 2.332   -62.105 -21.956 1.00 81.83  ? 195 ILE F O   1 
ATOM   4600 C CB  . ILE C 3 199 ? 2.748   -64.097 -19.634 1.00 82.93  ? 195 ILE F CB  1 
ATOM   4601 C CG1 . ILE C 3 199 ? 3.177   -65.544 -19.378 1.00 81.79  ? 195 ILE F CG1 1 
ATOM   4602 C CG2 . ILE C 3 199 ? 2.275   -63.444 -18.342 1.00 75.18  ? 195 ILE F CG2 1 
ATOM   4603 C CD1 . ILE C 3 199 ? 2.144   -66.373 -18.661 1.00 73.18  ? 195 ILE F CD1 1 
ATOM   4604 N N   . CYS C 3 200 ? 0.417   -61.931 -20.778 1.00 75.23  ? 196 CYS F N   1 
ATOM   4605 C CA  . CYS C 3 200 ? 0.222   -60.519 -21.077 1.00 76.32  ? 196 CYS F CA  1 
ATOM   4606 C C   . CYS C 3 200 ? 0.606   -59.697 -19.855 1.00 74.32  ? 196 CYS F C   1 
ATOM   4607 O O   . CYS C 3 200 ? 0.146   -59.972 -18.741 1.00 72.28  ? 196 CYS F O   1 
ATOM   4608 C CB  . CYS C 3 200 ? -1.221  -60.228 -21.502 1.00 80.76  ? 196 CYS F CB  1 
ATOM   4609 S SG  . CYS C 3 200 ? -2.489  -60.390 -20.223 1.00 94.44  ? 196 CYS F SG  1 
ATOM   4610 N N   . ASN C 3 201 ? 1.467   -58.706 -20.062 1.00 69.45  ? 197 ASN F N   1 
ATOM   4611 C CA  . ASN C 3 201 ? 1.981   -57.870 -18.986 1.00 68.89  ? 197 ASN F CA  1 
ATOM   4612 C C   . ASN C 3 201 ? 1.282   -56.519 -19.038 1.00 63.07  ? 197 ASN F C   1 
ATOM   4613 O O   . ASN C 3 201 ? 1.450   -55.765 -20.002 1.00 52.39  ? 197 ASN F O   1 
ATOM   4614 C CB  . ASN C 3 201 ? 3.494   -57.702 -19.103 1.00 78.98  ? 197 ASN F CB  1 
ATOM   4615 C CG  . ASN C 3 201 ? 4.203   -59.008 -19.402 1.00 76.98  ? 197 ASN F CG  1 
ATOM   4616 O OD1 . ASN C 3 201 ? 4.846   -59.154 -20.441 1.00 76.28  ? 197 ASN F OD1 1 
ATOM   4617 N ND2 . ASN C 3 201 ? 4.083   -59.969 -18.493 1.00 74.52  ? 197 ASN F ND2 1 
ATOM   4618 N N   . VAL C 3 202 ? 0.502   -56.218 -18.004 1.00 62.20  ? 198 VAL F N   1 
ATOM   4619 C CA  . VAL C 3 202 ? -0.295  -55.001 -17.936 1.00 57.91  ? 198 VAL F CA  1 
ATOM   4620 C C   . VAL C 3 202 ? 0.285   -54.107 -16.851 1.00 52.10  ? 198 VAL F C   1 
ATOM   4621 O O   . VAL C 3 202 ? 0.475   -54.547 -15.710 1.00 66.81  ? 198 VAL F O   1 
ATOM   4622 C CB  . VAL C 3 202 ? -1.775  -55.313 -17.660 1.00 61.57  ? 198 VAL F CB  1 
ATOM   4623 C CG1 . VAL C 3 202 ? -2.628  -54.078 -17.887 1.00 51.64  ? 198 VAL F CG1 1 
ATOM   4624 C CG2 . VAL C 3 202 ? -2.244  -56.468 -18.534 1.00 57.61  ? 198 VAL F CG2 1 
ATOM   4625 N N   . ASN C 3 203 ? 0.566   -52.855 -17.204 1.00 50.31  ? 199 ASN F N   1 
ATOM   4626 C CA  . ASN C 3 203 ? 1.133   -51.891 -16.272 1.00 58.30  ? 199 ASN F CA  1 
ATOM   4627 C C   . ASN C 3 203 ? 0.278   -50.633 -16.272 1.00 52.38  ? 199 ASN F C   1 
ATOM   4628 O O   . ASN C 3 203 ? -0.009  -50.073 -17.335 1.00 53.11  ? 199 ASN F O   1 
ATOM   4629 C CB  . ASN C 3 203 ? 2.581   -51.554 -16.642 1.00 59.87  ? 199 ASN F CB  1 
ATOM   4630 C CG  . ASN C 3 203 ? 3.355   -50.963 -15.481 1.00 62.63  ? 199 ASN F CG  1 
ATOM   4631 O OD1 . ASN C 3 203 ? 3.424   -49.745 -15.320 1.00 66.33  ? 199 ASN F OD1 1 
ATOM   4632 N ND2 . ASN C 3 203 ? 3.942   -51.828 -14.663 1.00 67.95  ? 199 ASN F ND2 1 
ATOM   4633 N N   . HIS C 3 204 ? -0.127  -50.195 -15.079 1.00 47.45  ? 200 HIS F N   1 
ATOM   4634 C CA  . HIS C 3 204 ? -0.913  -48.975 -14.892 1.00 54.29  ? 200 HIS F CA  1 
ATOM   4635 C C   . HIS C 3 204 ? -0.176  -48.132 -13.856 1.00 57.84  ? 200 HIS F C   1 
ATOM   4636 O O   . HIS C 3 204 ? -0.408  -48.267 -12.652 1.00 61.86  ? 200 HIS F O   1 
ATOM   4637 C CB  . HIS C 3 204 ? -2.343  -49.294 -14.464 1.00 42.81  ? 200 HIS F CB  1 
ATOM   4638 C CG  . HIS C 3 204 ? -3.209  -48.085 -14.298 1.00 41.40  ? 200 HIS F CG  1 
ATOM   4639 N ND1 . HIS C 3 204 ? -3.815  -47.763 -13.103 1.00 50.10  ? 200 HIS F ND1 1 
ATOM   4640 C CD2 . HIS C 3 204 ? -3.570  -47.118 -15.175 1.00 43.45  ? 200 HIS F CD2 1 
ATOM   4641 C CE1 . HIS C 3 204 ? -4.513  -46.650 -13.251 1.00 41.68  ? 200 HIS F CE1 1 
ATOM   4642 N NE2 . HIS C 3 204 ? -4.381  -46.239 -14.499 1.00 44.17  ? 200 HIS F NE2 1 
ATOM   4643 N N   . LYS C 3 205 ? 0.716   -47.267 -14.338 1.00 56.06  ? 201 LYS F N   1 
ATOM   4644 C CA  . LYS C 3 205 ? 1.560   -46.483 -13.439 1.00 57.02  ? 201 LYS F CA  1 
ATOM   4645 C C   . LYS C 3 205 ? 0.791   -45.592 -12.467 1.00 64.76  ? 201 LYS F C   1 
ATOM   4646 O O   . LYS C 3 205 ? 1.219   -45.499 -11.303 1.00 66.31  ? 201 LYS F O   1 
ATOM   4647 C CB  . LYS C 3 205 ? 2.557   -45.660 -14.265 1.00 62.74  ? 201 LYS F CB  1 
ATOM   4648 C CG  . LYS C 3 205 ? 3.477   -46.517 -15.119 1.00 65.72  ? 201 LYS F CG  1 
ATOM   4649 C CD  . LYS C 3 205 ? 4.756   -45.788 -15.485 1.00 80.18  ? 201 LYS F CD  1 
ATOM   4650 C CE  . LYS C 3 205 ? 5.731   -46.724 -16.183 1.00 82.70  ? 201 LYS F CE  1 
ATOM   4651 N NZ  . LYS C 3 205 ? 7.049   -46.080 -16.433 1.00 90.64  ? 201 LYS F NZ  1 
ATOM   4652 N N   . PRO C 3 206 ? -0.296  -44.902 -12.850 1.00 57.80  ? 202 PRO F N   1 
ATOM   4653 C CA  . PRO C 3 206 ? -0.993  -44.061 -11.858 1.00 56.83  ? 202 PRO F CA  1 
ATOM   4654 C C   . PRO C 3 206 ? -1.439  -44.811 -10.613 1.00 54.76  ? 202 PRO F C   1 
ATOM   4655 O O   . PRO C 3 206 ? -1.395  -44.248 -9.513  1.00 55.00  ? 202 PRO F O   1 
ATOM   4656 C CB  . PRO C 3 206 ? -2.186  -43.513 -12.652 1.00 59.76  ? 202 PRO F CB  1 
ATOM   4657 C CG  . PRO C 3 206 ? -1.698  -43.465 -14.047 1.00 56.91  ? 202 PRO F CG  1 
ATOM   4658 C CD  . PRO C 3 206 ? -0.828  -44.680 -14.208 1.00 54.45  ? 202 PRO F CD  1 
ATOM   4659 N N   . SER C 3 207 ? -1.869  -46.064 -10.748 1.00 57.83  ? 203 SER F N   1 
ATOM   4660 C CA  . SER C 3 207 ? -2.238  -46.878 -9.597  1.00 60.95  ? 203 SER F CA  1 
ATOM   4661 C C   . SER C 3 207 ? -1.145  -47.856 -9.188  1.00 64.74  ? 203 SER F C   1 
ATOM   4662 O O   . SER C 3 207 ? -1.344  -48.619 -8.237  1.00 63.46  ? 203 SER F O   1 
ATOM   4663 C CB  . SER C 3 207 ? -3.534  -47.644 -9.879  1.00 51.26  ? 203 SER F CB  1 
ATOM   4664 O OG  . SER C 3 207 ? -3.348  -48.601 -10.908 1.00 60.01  ? 203 SER F OG  1 
ATOM   4665 N N   . ASN C 3 208 ? -0.001  -47.846 -9.877  1.00 60.98  ? 204 ASN F N   1 
ATOM   4666 C CA  . ASN C 3 208 ? 1.120   -48.742 -9.582  1.00 69.63  ? 204 ASN F CA  1 
ATOM   4667 C C   . ASN C 3 208 ? 0.682   -50.206 -9.607  1.00 75.71  ? 204 ASN F C   1 
ATOM   4668 O O   . ASN C 3 208 ? 0.966   -50.983 -8.693  1.00 82.24  ? 204 ASN F O   1 
ATOM   4669 C CB  . ASN C 3 208 ? 1.774   -48.385 -8.244  1.00 70.67  ? 204 ASN F CB  1 
ATOM   4670 C CG  . ASN C 3 208 ? 2.339   -46.978 -8.229  1.00 67.34  ? 204 ASN F CG  1 
ATOM   4671 O OD1 . ASN C 3 208 ? 3.480   -46.751 -8.632  1.00 71.18  ? 204 ASN F OD1 1 
ATOM   4672 N ND2 . ASN C 3 208 ? 1.541   -46.025 -7.761  1.00 78.37  ? 204 ASN F ND2 1 
ATOM   4673 N N   . THR C 3 209 ? -0.019  -50.581 -10.674 1.00 66.57  ? 205 THR F N   1 
ATOM   4674 C CA  . THR C 3 209 ? -0.536  -51.933 -10.838 1.00 61.62  ? 205 THR F CA  1 
ATOM   4675 C C   . THR C 3 209 ? 0.310   -52.687 -11.856 1.00 64.59  ? 205 THR F C   1 
ATOM   4676 O O   . THR C 3 209 ? 0.523   -52.206 -12.974 1.00 65.25  ? 205 THR F O   1 
ATOM   4677 C CB  . THR C 3 209 ? -1.999  -51.908 -11.285 1.00 67.24  ? 205 THR F CB  1 
ATOM   4678 O OG1 . THR C 3 209 ? -2.774  -51.148 -10.349 1.00 68.98  ? 205 THR F OG1 1 
ATOM   4679 C CG2 . THR C 3 209 ? -2.556  -53.322 -11.361 1.00 50.98  ? 205 THR F CG2 1 
ATOM   4680 N N   . LYS C 3 210 ? 0.792   -53.865 -11.461 1.00 67.40  ? 206 LYS F N   1 
ATOM   4681 C CA  . LYS C 3 210 ? 1.607   -54.723 -12.316 1.00 66.68  ? 206 LYS F CA  1 
ATOM   4682 C C   . LYS C 3 210 ? 1.010   -56.122 -12.276 1.00 62.17  ? 206 LYS F C   1 
ATOM   4683 O O   . LYS C 3 210 ? 1.121   -56.816 -11.260 1.00 73.86  ? 206 LYS F O   1 
ATOM   4684 C CB  . LYS C 3 210 ? 3.063   -54.735 -11.853 1.00 80.63  ? 206 LYS F CB  1 
ATOM   4685 C CG  . LYS C 3 210 ? 3.680   -53.353 -11.721 1.00 82.67  ? 206 LYS F CG  1 
ATOM   4686 C CD  . LYS C 3 210 ? 4.745   -53.322 -10.637 1.00 97.62  ? 206 LYS F CD  1 
ATOM   4687 C CE  . LYS C 3 210 ? 5.329   -51.926 -10.481 1.00 101.18 ? 206 LYS F CE  1 
ATOM   4688 N NZ  . LYS C 3 210 ? 4.273   -50.906 -10.223 1.00 83.07  ? 206 LYS F NZ  1 
ATOM   4689 N N   . VAL C 3 211 ? 0.379   -56.538 -13.372 1.00 62.04  ? 207 VAL F N   1 
ATOM   4690 C CA  . VAL C 3 211 ? -0.325  -57.813 -13.438 1.00 63.97  ? 207 VAL F CA  1 
ATOM   4691 C C   . VAL C 3 211 ? 0.187   -58.602 -14.635 1.00 67.45  ? 207 VAL F C   1 
ATOM   4692 O O   . VAL C 3 211 ? 0.228   -58.084 -15.756 1.00 73.05  ? 207 VAL F O   1 
ATOM   4693 C CB  . VAL C 3 211 ? -1.851  -57.621 -13.537 1.00 50.48  ? 207 VAL F CB  1 
ATOM   4694 C CG1 . VAL C 3 211 ? -2.546  -58.965 -13.696 1.00 59.85  ? 207 VAL F CG1 1 
ATOM   4695 C CG2 . VAL C 3 211 ? -2.376  -56.889 -12.313 1.00 54.72  ? 207 VAL F CG2 1 
ATOM   4696 N N   . ASP C 3 212 ? 0.574   -59.852 -14.393 1.00 61.66  ? 208 ASP F N   1 
ATOM   4697 C CA  . ASP C 3 212 ? 0.902   -60.805 -15.444 1.00 72.15  ? 208 ASP F CA  1 
ATOM   4698 C C   . ASP C 3 212 ? -0.165  -61.890 -15.460 1.00 75.14  ? 208 ASP F C   1 
ATOM   4699 O O   . ASP C 3 212 ? -0.431  -62.518 -14.430 1.00 78.87  ? 208 ASP F O   1 
ATOM   4700 C CB  . ASP C 3 212 ? 2.286   -61.421 -15.223 1.00 78.42  ? 208 ASP F CB  1 
ATOM   4701 C CG  . ASP C 3 212 ? 3.408   -60.423 -15.421 1.00 83.58  ? 208 ASP F CG  1 
ATOM   4702 O OD1 . ASP C 3 212 ? 3.121   -59.267 -15.797 1.00 79.51  ? 208 ASP F OD1 1 
ATOM   4703 O OD2 . ASP C 3 212 ? 4.580   -60.797 -15.203 1.00 88.28  ? 208 ASP F OD2 1 
ATOM   4704 N N   . LYS C 3 213 ? -0.774  -62.107 -16.623 1.00 72.46  ? 209 LYS F N   1 
ATOM   4705 C CA  . LYS C 3 213 ? -1.899  -63.022 -16.759 1.00 68.70  ? 209 LYS F CA  1 
ATOM   4706 C C   . LYS C 3 213 ? -1.540  -64.111 -17.758 1.00 76.06  ? 209 LYS F C   1 
ATOM   4707 O O   . LYS C 3 213 ? -1.192  -63.814 -18.906 1.00 72.97  ? 209 LYS F O   1 
ATOM   4708 C CB  . LYS C 3 213 ? -3.157  -62.277 -17.209 1.00 61.99  ? 209 LYS F CB  1 
ATOM   4709 C CG  . LYS C 3 213 ? -4.433  -63.096 -17.127 1.00 62.69  ? 209 LYS F CG  1 
ATOM   4710 C CD  . LYS C 3 213 ? -4.824  -63.360 -15.682 1.00 51.99  ? 209 LYS F CD  1 
ATOM   4711 C CE  . LYS C 3 213 ? -4.863  -62.065 -14.882 1.00 56.94  ? 209 LYS F CE  1 
ATOM   4712 N NZ  . LYS C 3 213 ? -5.517  -62.235 -13.555 1.00 56.71  ? 209 LYS F NZ  1 
ATOM   4713 N N   . LYS C 3 214 ? -1.622  -65.365 -17.325 1.00 74.80  ? 210 LYS F N   1 
ATOM   4714 C CA  . LYS C 3 214 ? -1.422  -66.482 -18.236 1.00 77.69  ? 210 LYS F CA  1 
ATOM   4715 C C   . LYS C 3 214 ? -2.695  -66.703 -19.042 1.00 79.72  ? 210 LYS F C   1 
ATOM   4716 O O   . LYS C 3 214 ? -3.795  -66.721 -18.483 1.00 82.98  ? 210 LYS F O   1 
ATOM   4717 C CB  . LYS C 3 214 ? -1.045  -67.750 -17.468 1.00 79.95  ? 210 LYS F CB  1 
ATOM   4718 C CG  . LYS C 3 214 ? -0.840  -68.958 -18.368 1.00 90.30  ? 210 LYS F CG  1 
ATOM   4719 C CD  . LYS C 3 214 ? -0.265  -70.146 -17.615 1.00 90.42  ? 210 LYS F CD  1 
ATOM   4720 C CE  . LYS C 3 214 ? -0.125  -71.352 -18.533 1.00 85.61  ? 210 LYS F CE  1 
ATOM   4721 N NZ  . LYS C 3 214 ? 0.696   -71.047 -19.740 1.00 76.67  ? 210 LYS F NZ  1 
ATOM   4722 N N   . VAL C 3 215 ? -2.555  -66.863 -20.350 1.00 80.47  ? 211 VAL F N   1 
ATOM   4723 C CA  . VAL C 3 215 ? -3.704  -67.076 -21.231 1.00 75.74  ? 211 VAL F CA  1 
ATOM   4724 C C   . VAL C 3 215 ? -3.496  -68.421 -21.912 1.00 80.77  ? 211 VAL F C   1 
ATOM   4725 O O   . VAL C 3 215 ? -2.731  -68.550 -22.873 1.00 86.97  ? 211 VAL F O   1 
ATOM   4726 C CB  . VAL C 3 215 ? -3.891  -65.950 -22.249 1.00 73.69  ? 211 VAL F CB  1 
ATOM   4727 C CG1 . VAL C 3 215 ? -5.037  -66.280 -23.230 1.00 89.94  ? 211 VAL F CG1 1 
ATOM   4728 C CG2 . VAL C 3 215 ? -4.164  -64.645 -21.524 1.00 77.14  ? 211 VAL F CG2 1 
ATOM   4729 N N   . GLU C 3 216 ? -4.184  -69.431 -21.413 1.00 91.05  ? 212 GLU F N   1 
ATOM   4730 C CA  . GLU C 3 216 ? -4.124  -70.753 -21.991 1.00 96.00  ? 212 GLU F CA  1 
ATOM   4731 C C   . GLU C 3 216 ? -5.490  -71.161 -22.535 1.00 101.34 ? 212 GLU F C   1 
ATOM   4732 O O   . GLU C 3 216 ? -6.526  -70.696 -22.048 1.00 92.00  ? 212 GLU F O   1 
ATOM   4733 C CB  . GLU C 3 216 ? -3.660  -71.782 -20.954 1.00 102.09 ? 212 GLU F CB  1 
ATOM   4734 C CG  . GLU C 3 216 ? -4.612  -71.968 -19.787 1.00 109.33 ? 212 GLU F CG  1 
ATOM   4735 C CD  . GLU C 3 216 ? -4.289  -73.207 -18.976 1.00 119.27 ? 212 GLU F CD  1 
ATOM   4736 O OE1 . GLU C 3 216 ? -3.389  -73.968 -19.390 1.00 117.98 ? 212 GLU F OE1 1 
ATOM   4737 O OE2 . GLU C 3 216 ? -4.934  -73.421 -17.929 1.00 120.51 ? 212 GLU F OE2 1 
ATOM   4738 N N   . PRO C 3 217 ? -5.524  -72.013 -23.555 1.00 97.77  ? 213 PRO F N   1 
ATOM   4739 C CA  . PRO C 3 217 ? -6.810  -72.483 -24.077 1.00 90.00  ? 213 PRO F CA  1 
ATOM   4740 C C   . PRO C 3 217 ? -7.558  -73.321 -23.053 1.00 93.80  ? 213 PRO F C   1 
ATOM   4741 O O   . PRO C 3 217 ? -6.964  -73.985 -22.200 1.00 100.34 ? 213 PRO F O   1 
ATOM   4742 C CB  . PRO C 3 217 ? -6.413  -73.320 -25.299 1.00 93.66  ? 213 PRO F CB  1 
ATOM   4743 C CG  . PRO C 3 217 ? -4.997  -73.722 -25.036 1.00 99.97  ? 213 PRO F CG  1 
ATOM   4744 C CD  . PRO C 3 217 ? -4.385  -72.569 -24.305 1.00 94.84  ? 213 PRO F CD  1 
ATOM   4745 N N   . LYS C 3 218 ? -8.883  -73.276 -23.146 1.00 90.63  ? 214 LYS F N   1 
ATOM   4746 C CA  . LYS C 3 218 ? -9.744  -74.049 -22.258 1.00 85.63  ? 214 LYS F CA  1 
ATOM   4747 C C   . LYS C 3 218 ? -10.423 -75.191 -23.006 1.00 90.45  ? 214 LYS F C   1 
ATOM   4748 O O   . LYS C 3 218 ? -11.493 -75.654 -22.609 1.00 93.36  ? 214 LYS F O   1 
ATOM   4749 C CB  . LYS C 3 218 ? -10.796 -73.147 -21.610 1.00 84.42  ? 214 LYS F CB  1 
ATOM   4750 C CG  . LYS C 3 218 ? -10.320 -72.439 -20.354 1.00 92.16  ? 214 LYS F CG  1 
ATOM   4751 C CD  . LYS C 3 218 ? -10.038 -73.435 -19.241 1.00 91.01  ? 214 LYS F CD  1 
ATOM   4752 C CE  . LYS C 3 218 ? -11.277 -74.253 -18.909 1.00 82.46  ? 214 LYS F CE  1 
ATOM   4753 N NZ  . LYS C 3 218 ? -11.012 -75.254 -17.839 1.00 68.84  ? 214 LYS F NZ  1 
ATOM   4754 N N   . ASP D 4 1   ? -2.284  4.363   -4.070  1.00 47.58  ? 1   ASP L N   1 
ATOM   4755 C CA  . ASP D 4 1   ? -1.474  4.011   -2.910  1.00 46.62  ? 1   ASP L CA  1 
ATOM   4756 C C   . ASP D 4 1   ? -0.978  5.259   -2.186  1.00 40.58  ? 1   ASP L C   1 
ATOM   4757 O O   . ASP D 4 1   ? -0.811  5.252   -0.967  1.00 45.13  ? 1   ASP L O   1 
ATOM   4758 C CB  . ASP D 4 1   ? -0.290  3.135   -3.328  1.00 48.75  ? 1   ASP L CB  1 
ATOM   4759 C CG  . ASP D 4 1   ? 0.540   3.762   -4.432  1.00 68.71  ? 1   ASP L CG  1 
ATOM   4760 O OD1 . ASP D 4 1   ? -0.043  4.442   -5.304  1.00 67.33  ? 1   ASP L OD1 1 
ATOM   4761 O OD2 . ASP D 4 1   ? 1.775   3.575   -4.428  1.00 58.66  ? 1   ASP L OD2 1 
ATOM   4762 N N   . ILE D 4 2   ? -0.747  6.329   -2.941  1.00 37.74  ? 2   ILE L N   1 
ATOM   4763 C CA  . ILE D 4 2   ? -0.315  7.596   -2.359  1.00 36.09  ? 2   ILE L CA  1 
ATOM   4764 C C   . ILE D 4 2   ? -1.545  8.330   -1.841  1.00 33.25  ? 2   ILE L C   1 
ATOM   4765 O O   . ILE D 4 2   ? -2.473  8.621   -2.603  1.00 33.25  ? 2   ILE L O   1 
ATOM   4766 C CB  . ILE D 4 2   ? 0.447   8.448   -3.383  1.00 38.92  ? 2   ILE L CB  1 
ATOM   4767 C CG1 . ILE D 4 2   ? 1.604   7.653   -3.991  1.00 32.13  ? 2   ILE L CG1 1 
ATOM   4768 C CG2 . ILE D 4 2   ? 0.965   9.720   -2.730  1.00 27.34  ? 2   ILE L CG2 1 
ATOM   4769 C CD1 . ILE D 4 2   ? 2.361   8.403   -5.067  1.00 17.05  ? 2   ILE L CD1 1 
ATOM   4770 N N   . VAL D 4 3   ? -1.555  8.630   -0.546  1.00 33.08  ? 3   VAL L N   1 
ATOM   4771 C CA  . VAL D 4 3   ? -2.684  9.282   0.107   1.00 28.17  ? 3   VAL L CA  1 
ATOM   4772 C C   . VAL D 4 3   ? -2.383  10.767  0.234   1.00 29.47  ? 3   VAL L C   1 
ATOM   4773 O O   . VAL D 4 3   ? -1.294  11.154  0.678   1.00 30.81  ? 3   VAL L O   1 
ATOM   4774 C CB  . VAL D 4 3   ? -2.968  8.657   1.484   1.00 21.50  ? 3   VAL L CB  1 
ATOM   4775 C CG1 . VAL D 4 3   ? -4.127  9.370   2.164   1.00 19.79  ? 3   VAL L CG1 1 
ATOM   4776 C CG2 . VAL D 4 3   ? -3.261  7.173   1.340   1.00 24.28  ? 3   VAL L CG2 1 
ATOM   4777 N N   . MET D 4 4   ? -3.342  11.599  -0.163  1.00 25.50  ? 4   MET L N   1 
ATOM   4778 C CA  . MET D 4 4   ? -3.228  13.048  -0.069  1.00 23.83  ? 4   MET L CA  1 
ATOM   4779 C C   . MET D 4 4   ? -4.194  13.551  0.994   1.00 23.21  ? 4   MET L C   1 
ATOM   4780 O O   . MET D 4 4   ? -5.396  13.274  0.926   1.00 23.70  ? 4   MET L O   1 
ATOM   4781 C CB  . MET D 4 4   ? -3.529  13.707  -1.417  1.00 23.10  ? 4   MET L CB  1 
ATOM   4782 C CG  . MET D 4 4   ? -2.843  13.043  -2.601  1.00 21.39  ? 4   MET L CG  1 
ATOM   4783 S SD  . MET D 4 4   ? -1.056  13.279  -2.620  1.00 31.38  ? 4   MET L SD  1 
ATOM   4784 C CE  . MET D 4 4   ? -0.950  15.005  -3.078  1.00 36.47  ? 4   MET L CE  1 
ATOM   4785 N N   . THR D 4 5   ? -3.668  14.284  1.972   1.00 26.32  ? 5   THR L N   1 
ATOM   4786 C CA  . THR D 4 5   ? -4.457  14.820  3.073   1.00 29.72  ? 5   THR L CA  1 
ATOM   4787 C C   . THR D 4 5   ? -4.358  16.337  3.068   1.00 30.30  ? 5   THR L C   1 
ATOM   4788 O O   . THR D 4 5   ? -3.253  16.891  3.057   1.00 30.60  ? 5   THR L O   1 
ATOM   4789 C CB  . THR D 4 5   ? -3.983  14.262  4.419   1.00 30.82  ? 5   THR L CB  1 
ATOM   4790 O OG1 . THR D 4 5   ? -4.106  12.834  4.419   1.00 30.12  ? 5   THR L OG1 1 
ATOM   4791 C CG2 . THR D 4 5   ? -4.815  14.836  5.558   1.00 22.29  ? 5   THR L CG2 1 
ATOM   4792 N N   . GLN D 4 6   ? -5.508  17.004  3.082   1.00 28.08  ? 6   GLN L N   1 
ATOM   4793 C CA  . GLN D 4 6   ? -5.569  18.456  3.037   1.00 26.38  ? 6   GLN L CA  1 
ATOM   4794 C C   . GLN D 4 6   ? -5.880  19.027  4.415   1.00 31.93  ? 6   GLN L C   1 
ATOM   4795 O O   . GLN D 4 6   ? -6.561  18.400  5.231   1.00 37.58  ? 6   GLN L O   1 
ATOM   4796 C CB  . GLN D 4 6   ? -6.621  18.930  2.033   1.00 20.57  ? 6   GLN L CB  1 
ATOM   4797 C CG  . GLN D 4 6   ? -6.372  18.456  0.615   1.00 21.81  ? 6   GLN L CG  1 
ATOM   4798 C CD  . GLN D 4 6   ? -7.327  19.071  -0.388  1.00 25.30  ? 6   GLN L CD  1 
ATOM   4799 O OE1 . GLN D 4 6   ? -7.677  18.449  -1.391  1.00 29.01  ? 6   GLN L OE1 1 
ATOM   4800 N NE2 . GLN D 4 6   ? -7.748  20.303  -0.127  1.00 23.20  ? 6   GLN L NE2 1 
ATOM   4801 N N   . SER D 4 7   ? -5.366  20.233  4.665   1.00 31.70  ? 7   SER L N   1 
ATOM   4802 C CA  . SER D 4 7   ? -5.583  20.937  5.916   1.00 36.33  ? 7   SER L CA  1 
ATOM   4803 C C   . SER D 4 7   ? -5.781  22.416  5.602   1.00 37.06  ? 7   SER L C   1 
ATOM   4804 O O   . SER D 4 7   ? -4.958  23.009  4.880   1.00 35.20  ? 7   SER L O   1 
ATOM   4805 C CB  . SER D 4 7   ? -4.410  20.747  6.881   1.00 32.43  ? 7   SER L CB  1 
ATOM   4806 O OG  . SER D 4 7   ? -4.581  21.529  8.050   1.00 43.73  ? 7   SER L OG  1 
ATOM   4807 N N   . PRO D 4 8   ? -6.848  23.040  6.114   1.00 36.01  ? 8   PRO L N   1 
ATOM   4808 C CA  . PRO D 4 8   ? -7.934  22.456  6.911   1.00 32.82  ? 8   PRO L CA  1 
ATOM   4809 C C   . PRO D 4 8   ? -9.046  21.893  6.032   1.00 37.87  ? 8   PRO L C   1 
ATOM   4810 O O   . PRO D 4 8   ? -8.973  21.969  4.809   1.00 41.63  ? 8   PRO L O   1 
ATOM   4811 C CB  . PRO D 4 8   ? -8.409  23.648  7.746   1.00 25.04  ? 8   PRO L CB  1 
ATOM   4812 C CG  . PRO D 4 8   ? -8.227  24.815  6.817   1.00 32.54  ? 8   PRO L CG  1 
ATOM   4813 C CD  . PRO D 4 8   ? -6.972  24.507  6.025   1.00 30.68  ? 8   PRO L CD  1 
ATOM   4814 N N   . ASP D 4 9   ? -10.087 21.308  6.631   1.00 34.90  ? 9   ASP L N   1 
ATOM   4815 C CA  . ASP D 4 9   ? -11.219 20.833  5.840   1.00 36.60  ? 9   ASP L CA  1 
ATOM   4816 C C   . ASP D 4 9   ? -12.086 21.993  5.364   1.00 34.98  ? 9   ASP L C   1 
ATOM   4817 O O   . ASP D 4 9   ? -12.552 21.997  4.219   1.00 38.15  ? 9   ASP L O   1 
ATOM   4818 C CB  . ASP D 4 9   ? -12.047 19.838  6.652   1.00 38.08  ? 9   ASP L CB  1 
ATOM   4819 C CG  . ASP D 4 9   ? -11.329 18.518  6.860   1.00 47.91  ? 9   ASP L CG  1 
ATOM   4820 O OD1 . ASP D 4 9   ? -10.638 18.063  5.924   1.00 42.47  ? 9   ASP L OD1 1 
ATOM   4821 O OD2 . ASP D 4 9   ? -11.456 17.936  7.958   1.00 49.59  ? 9   ASP L OD2 1 
ATOM   4822 N N   . SER D 4 10  ? -12.316 22.982  6.226   1.00 37.78  ? 10  SER L N   1 
ATOM   4823 C CA  . SER D 4 10  ? -13.086 24.168  5.881   1.00 34.08  ? 10  SER L CA  1 
ATOM   4824 C C   . SER D 4 10  ? -12.293 25.410  6.259   1.00 38.02  ? 10  SER L C   1 
ATOM   4825 O O   . SER D 4 10  ? -11.656 25.454  7.316   1.00 40.62  ? 10  SER L O   1 
ATOM   4826 C CB  . SER D 4 10  ? -14.450 24.181  6.584   1.00 36.74  ? 10  SER L CB  1 
ATOM   4827 O OG  . SER D 4 10  ? -15.307 23.188  6.050   1.00 44.32  ? 10  SER L OG  1 
ATOM   4828 N N   . LEU D 4 11  ? -12.336 26.418  5.389   1.00 37.59  ? 11  LEU L N   1 
ATOM   4829 C CA  . LEU D 4 11  ? -11.568 27.642  5.566   1.00 43.87  ? 11  LEU L CA  1 
ATOM   4830 C C   . LEU D 4 11  ? -12.476 28.844  5.356   1.00 39.06  ? 11  LEU L C   1 
ATOM   4831 O O   . LEU D 4 11  ? -13.250 28.881  4.393   1.00 33.95  ? 11  LEU L O   1 
ATOM   4832 C CB  . LEU D 4 11  ? -10.385 27.689  4.591   1.00 36.39  ? 11  LEU L CB  1 
ATOM   4833 C CG  . LEU D 4 11  ? -9.339  28.785  4.799   1.00 45.04  ? 11  LEU L CG  1 
ATOM   4834 C CD1 . LEU D 4 11  ? -8.678  28.642  6.160   1.00 47.53  ? 11  LEU L CD1 1 
ATOM   4835 C CD2 . LEU D 4 11  ? -8.301  28.745  3.688   1.00 36.89  ? 11  LEU L CD2 1 
ATOM   4836 N N   . ALA D 4 12  ? -12.383 29.819  6.258   1.00 30.92  ? 12  ALA L N   1 
ATOM   4837 C CA  . ALA D 4 12  ? -13.148 31.060  6.174   1.00 37.36  ? 12  ALA L CA  1 
ATOM   4838 C C   . ALA D 4 12  ? -12.163 32.221  6.131   1.00 35.65  ? 12  ALA L C   1 
ATOM   4839 O O   . ALA D 4 12  ? -11.457 32.479  7.112   1.00 33.24  ? 12  ALA L O   1 
ATOM   4840 C CB  . ALA D 4 12  ? -14.111 31.194  7.352   1.00 31.25  ? 12  ALA L CB  1 
ATOM   4841 N N   . VAL D 4 13  ? -12.116 32.917  4.997   1.00 28.68  ? 13  VAL L N   1 
ATOM   4842 C CA  . VAL D 4 13  ? -11.186 34.019  4.780   1.00 38.26  ? 13  VAL L CA  1 
ATOM   4843 C C   . VAL D 4 13  ? -11.979 35.240  4.339   1.00 40.07  ? 13  VAL L C   1 
ATOM   4844 O O   . VAL D 4 13  ? -12.816 35.149  3.434   1.00 26.71  ? 13  VAL L O   1 
ATOM   4845 C CB  . VAL D 4 13  ? -10.112 33.662  3.733   1.00 30.01  ? 13  VAL L CB  1 
ATOM   4846 C CG1 . VAL D 4 13  ? -9.221  34.862  3.450   1.00 38.06  ? 13  VAL L CG1 1 
ATOM   4847 C CG2 . VAL D 4 13  ? -9.282  32.480  4.209   1.00 31.51  ? 13  VAL L CG2 1 
ATOM   4848 N N   . SER D 4 14  ? -11.716 36.378  4.978   1.00 44.65  ? 14  SER L N   1 
ATOM   4849 C CA  . SER D 4 14  ? -12.394 37.616  4.629   1.00 38.21  ? 14  SER L CA  1 
ATOM   4850 C C   . SER D 4 14  ? -11.942 38.105  3.255   1.00 41.96  ? 14  SER L C   1 
ATOM   4851 O O   . SER D 4 14  ? -10.895 37.707  2.736   1.00 42.84  ? 14  SER L O   1 
ATOM   4852 C CB  . SER D 4 14  ? -12.126 38.690  5.684   1.00 40.65  ? 14  SER L CB  1 
ATOM   4853 O OG  . SER D 4 14  ? -12.507 38.245  6.974   1.00 52.07  ? 14  SER L OG  1 
ATOM   4854 N N   . LEU D 4 15  ? -12.759 38.974  2.662   1.00 36.62  ? 15  LEU L N   1 
ATOM   4855 C CA  . LEU D 4 15  ? -12.439 39.530  1.354   1.00 37.88  ? 15  LEU L CA  1 
ATOM   4856 C C   . LEU D 4 15  ? -11.120 40.292  1.404   1.00 46.23  ? 15  LEU L C   1 
ATOM   4857 O O   . LEU D 4 15  ? -10.902 41.126  2.287   1.00 45.25  ? 15  LEU L O   1 
ATOM   4858 C CB  . LEU D 4 15  ? -13.563 40.453  0.883   1.00 30.51  ? 15  LEU L CB  1 
ATOM   4859 C CG  . LEU D 4 15  ? -14.874 39.796  0.451   1.00 46.49  ? 15  LEU L CG  1 
ATOM   4860 C CD1 . LEU D 4 15  ? -15.954 40.845  0.250   1.00 28.07  ? 15  LEU L CD1 1 
ATOM   4861 C CD2 . LEU D 4 15  ? -14.667 38.991  -0.823  1.00 35.90  ? 15  LEU L CD2 1 
ATOM   4862 N N   . GLY D 4 16  ? -10.237 39.996  0.452   1.00 48.29  ? 16  GLY L N   1 
ATOM   4863 C CA  . GLY D 4 16  ? -8.953  40.653  0.364   1.00 40.27  ? 16  GLY L CA  1 
ATOM   4864 C C   . GLY D 4 16  ? -7.861  40.065  1.229   1.00 43.72  ? 16  GLY L C   1 
ATOM   4865 O O   . GLY D 4 16  ? -6.687  40.401  1.027   1.00 46.34  ? 16  GLY L O   1 
ATOM   4866 N N   . GLU D 4 17  ? -8.196  39.194  2.178   1.00 47.34  ? 17  GLU L N   1 
ATOM   4867 C CA  . GLU D 4 17  ? -7.198  38.587  3.047   1.00 37.91  ? 17  GLU L CA  1 
ATOM   4868 C C   . GLU D 4 17  ? -6.559  37.393  2.339   1.00 41.20  ? 17  GLU L C   1 
ATOM   4869 O O   . GLU D 4 17  ? -6.830  37.112  1.168   1.00 38.57  ? 17  GLU L O   1 
ATOM   4870 C CB  . GLU D 4 17  ? -7.821  38.194  4.384   1.00 33.92  ? 17  GLU L CB  1 
ATOM   4871 C CG  . GLU D 4 17  ? -8.003  39.352  5.352   1.00 48.37  ? 17  GLU L CG  1 
ATOM   4872 C CD  . GLU D 4 17  ? -8.580  38.910  6.683   1.00 77.86  ? 17  GLU L CD  1 
ATOM   4873 O OE1 . GLU D 4 17  ? -8.569  39.719  7.636   1.00 68.43  ? 17  GLU L OE1 1 
ATOM   4874 O OE2 . GLU D 4 17  ? -9.042  37.753  6.778   1.00 75.54  ? 17  GLU L OE2 1 
ATOM   4875 N N   . ARG D 4 18  ? -5.705  36.669  3.055   1.00 48.97  ? 18  ARG L N   1 
ATOM   4876 C CA  . ARG D 4 18  ? -4.919  35.584  2.483   1.00 47.06  ? 18  ARG L CA  1 
ATOM   4877 C C   . ARG D 4 18  ? -5.516  34.240  2.879   1.00 42.82  ? 18  ARG L C   1 
ATOM   4878 O O   . ARG D 4 18  ? -5.789  33.999  4.060   1.00 44.94  ? 18  ARG L O   1 
ATOM   4879 C CB  . ARG D 4 18  ? -3.465  35.677  2.945   1.00 58.92  ? 18  ARG L CB  1 
ATOM   4880 C CG  . ARG D 4 18  ? -2.547  34.608  2.382   1.00 56.69  ? 18  ARG L CG  1 
ATOM   4881 C CD  . ARG D 4 18  ? -1.101  34.913  2.735   1.00 59.48  ? 18  ARG L CD  1 
ATOM   4882 N NE  . ARG D 4 18  ? -0.685  36.209  2.210   1.00 73.74  ? 18  ARG L NE  1 
ATOM   4883 C CZ  . ARG D 4 18  ? 0.074   36.375  1.135   1.00 60.83  ? 18  ARG L CZ  1 
ATOM   4884 N NH1 . ARG D 4 18  ? 0.556   35.343  0.462   1.00 61.22  ? 18  ARG L NH1 1 
ATOM   4885 N NH2 . ARG D 4 18  ? 0.360   37.608  0.727   1.00 51.97  ? 18  ARG L NH2 1 
ATOM   4886 N N   . ALA D 4 19  ? -5.714  33.372  1.891   1.00 39.90  ? 19  ALA L N   1 
ATOM   4887 C CA  . ALA D 4 19  ? -6.226  32.026  2.103   1.00 36.67  ? 19  ALA L CA  1 
ATOM   4888 C C   . ALA D 4 19  ? -5.094  31.027  1.915   1.00 34.68  ? 19  ALA L C   1 
ATOM   4889 O O   . ALA D 4 19  ? -4.391  31.064  0.900   1.00 35.74  ? 19  ALA L O   1 
ATOM   4890 C CB  . ALA D 4 19  ? -7.375  31.716  1.142   1.00 39.41  ? 19  ALA L CB  1 
ATOM   4891 N N   . THR D 4 20  ? -4.920  30.140  2.892   1.00 29.77  ? 20  THR L N   1 
ATOM   4892 C CA  . THR D 4 20  ? -3.844  29.156  2.882   1.00 39.63  ? 20  THR L CA  1 
ATOM   4893 C C   . THR D 4 20  ? -4.442  27.763  3.017   1.00 37.31  ? 20  THR L C   1 
ATOM   4894 O O   . THR D 4 20  ? -5.162  27.483  3.982   1.00 33.67  ? 20  THR L O   1 
ATOM   4895 C CB  . THR D 4 20  ? -2.844  29.424  4.009   1.00 42.68  ? 20  THR L CB  1 
ATOM   4896 O OG1 . THR D 4 20  ? -2.201  30.686  3.789   1.00 44.40  ? 20  THR L OG1 1 
ATOM   4897 C CG2 . THR D 4 20  ? -1.793  28.325  4.064   1.00 44.07  ? 20  THR L CG2 1 
ATOM   4898 N N   . ILE D 4 21  ? -4.142  26.897  2.052   1.00 33.57  ? 21  ILE L N   1 
ATOM   4899 C CA  . ILE D 4 21  ? -4.603  25.514  2.046   1.00 30.27  ? 21  ILE L CA  1 
ATOM   4900 C C   . ILE D 4 21  ? -3.388  24.614  1.879   1.00 36.11  ? 21  ILE L C   1 
ATOM   4901 O O   . ILE D 4 21  ? -2.598  24.799  0.946   1.00 40.32  ? 21  ILE L O   1 
ATOM   4902 C CB  . ILE D 4 21  ? -5.628  25.257  0.925   1.00 25.09  ? 21  ILE L CB  1 
ATOM   4903 C CG1 . ILE D 4 21  ? -6.815  26.214  1.056   1.00 20.73  ? 21  ILE L CG1 1 
ATOM   4904 C CG2 . ILE D 4 21  ? -6.100  23.812  0.955   1.00 27.78  ? 21  ILE L CG2 1 
ATOM   4905 C CD1 . ILE D 4 21  ? -7.784  26.143  -0.102  1.00 24.37  ? 21  ILE L CD1 1 
ATOM   4906 N N   . ASN D 4 22  ? -3.241  23.642  2.774   1.00 29.62  ? 22  ASN L N   1 
ATOM   4907 C CA  . ASN D 4 22  ? -2.086  22.758  2.787   1.00 36.07  ? 22  ASN L CA  1 
ATOM   4908 C C   . ASN D 4 22  ? -2.483  21.355  2.346   1.00 34.57  ? 22  ASN L C   1 
ATOM   4909 O O   . ASN D 4 22  ? -3.593  20.889  2.619   1.00 37.54  ? 22  ASN L O   1 
ATOM   4910 C CB  . ASN D 4 22  ? -1.451  22.702  4.179   1.00 31.94  ? 22  ASN L CB  1 
ATOM   4911 C CG  . ASN D 4 22  ? -1.150  24.080  4.738   1.00 49.03  ? 22  ASN L CG  1 
ATOM   4912 O OD1 . ASN D 4 22  ? -0.141  24.695  4.394   1.00 51.75  ? 22  ASN L OD1 1 
ATOM   4913 N ND2 . ASN D 4 22  ? -2.028  24.571  5.606   1.00 36.45  ? 22  ASN L ND2 1 
ATOM   4914 N N   . CYS D 4 23  ? -1.560  20.690  1.658   1.00 32.17  ? 23  CYS L N   1 
ATOM   4915 C CA  . CYS D 4 23  ? -1.745  19.326  1.182   1.00 34.11  ? 23  CYS L CA  1 
ATOM   4916 C C   . CYS D 4 23  ? -0.523  18.512  1.582   1.00 33.30  ? 23  CYS L C   1 
ATOM   4917 O O   . CYS D 4 23  ? 0.611   18.919  1.311   1.00 36.19  ? 23  CYS L O   1 
ATOM   4918 C CB  . CYS D 4 23  ? -1.943  19.301  -0.340  1.00 25.02  ? 23  CYS L CB  1 
ATOM   4919 S SG  . CYS D 4 23  ? -2.214  17.678  -1.102  1.00 47.95  ? 23  CYS L SG  1 
ATOM   4920 N N   . LYS D 4 24  ? -0.754  17.373  2.229   1.00 24.75  ? 24  LYS L N   1 
ATOM   4921 C CA  . LYS D 4 24  ? 0.313   16.501  2.702   1.00 31.10  ? 24  LYS L CA  1 
ATOM   4922 C C   . LYS D 4 24  ? 0.261   15.189  1.931   1.00 37.13  ? 24  LYS L C   1 
ATOM   4923 O O   . LYS D 4 24  ? -0.813  14.601  1.770   1.00 39.23  ? 24  LYS L O   1 
ATOM   4924 C CB  . LYS D 4 24  ? 0.185   16.249  4.208   1.00 37.50  ? 24  LYS L CB  1 
ATOM   4925 C CG  . LYS D 4 24  ? 1.484   15.864  4.914   1.00 43.50  ? 24  LYS L CG  1 
ATOM   4926 C CD  . LYS D 4 24  ? 1.806   14.383  4.767   1.00 51.17  ? 24  LYS L CD  1 
ATOM   4927 C CE  . LYS D 4 24  ? 3.056   14.007  5.548   1.00 52.67  ? 24  LYS L CE  1 
ATOM   4928 N NZ  . LYS D 4 24  ? 3.444   12.586  5.325   1.00 52.40  ? 24  LYS L NZ  1 
ATOM   4929 N N   . SER D 4 25  ? 1.418   14.738  1.458   1.00 33.38  ? 25  SER L N   1 
ATOM   4930 C CA  . SER D 4 25  ? 1.531   13.527  0.658   1.00 35.20  ? 25  SER L CA  1 
ATOM   4931 C C   . SER D 4 25  ? 2.207   12.437  1.479   1.00 38.63  ? 25  SER L C   1 
ATOM   4932 O O   . SER D 4 25  ? 3.229   12.686  2.126   1.00 44.85  ? 25  SER L O   1 
ATOM   4933 C CB  . SER D 4 25  ? 2.319   13.796  -0.625  1.00 31.11  ? 25  SER L CB  1 
ATOM   4934 O OG  . SER D 4 25  ? 2.347   12.652  -1.460  1.00 46.84  ? 25  SER L OG  1 
ATOM   4935 N N   . SER D 4 26  ? 1.631   11.232  1.455   1.00 30.05  ? 26  SER L N   1 
ATOM   4936 C CA  . SER D 4 26  ? 2.207   10.119  2.200   1.00 41.10  ? 26  SER L CA  1 
ATOM   4937 C C   . SER D 4 26  ? 3.537   9.659   1.618   1.00 31.82  ? 26  SER L C   1 
ATOM   4938 O O   . SER D 4 26  ? 4.337   9.052   2.337   1.00 32.55  ? 26  SER L O   1 
ATOM   4939 C CB  . SER D 4 26  ? 1.226   8.947   2.243   1.00 34.13  ? 26  SER L CB  1 
ATOM   4940 O OG  . SER D 4 26  ? 1.028   8.400   0.951   1.00 38.31  ? 26  SER L OG  1 
ATOM   4941 N N   . GLN D 4 27  ? 3.785   9.924   0.337   1.00 34.67  ? 27  GLN L N   1 
ATOM   4942 C CA  . GLN D 4 27  ? 5.047   9.593   -0.307  1.00 32.20  ? 27  GLN L CA  1 
ATOM   4943 C C   . GLN D 4 27  ? 5.468   10.764  -1.183  1.00 40.63  ? 27  GLN L C   1 
ATOM   4944 O O   . GLN D 4 27  ? 4.690   11.687  -1.439  1.00 36.57  ? 27  GLN L O   1 
ATOM   4945 C CB  . GLN D 4 27  ? 4.941   8.315   -1.150  1.00 23.81  ? 27  GLN L CB  1 
ATOM   4946 C CG  . GLN D 4 27  ? 4.313   7.127   -0.443  1.00 32.87  ? 27  GLN L CG  1 
ATOM   4947 C CD  . GLN D 4 27  ? 4.140   5.937   -1.364  1.00 37.69  ? 27  GLN L CD  1 
ATOM   4948 O OE1 . GLN D 4 27  ? 4.835   5.813   -2.373  1.00 30.55  ? 27  GLN L OE1 1 
ATOM   4949 N NE2 . GLN D 4 27  ? 3.204   5.057   -1.027  1.00 35.60  ? 27  GLN L NE2 1 
ATOM   4950 N N   . SER D 4 28  A 6.716   10.725  -1.644  1.00 37.52  ? 27  SER L N   1 
ATOM   4951 C CA  . SER D 4 28  A 7.180   11.718  -2.600  1.00 41.17  ? 27  SER L CA  1 
ATOM   4952 C C   . SER D 4 28  A 6.426   11.567  -3.917  1.00 43.27  ? 27  SER L C   1 
ATOM   4953 O O   . SER D 4 28  A 6.013   10.469  -4.299  1.00 33.37  ? 27  SER L O   1 
ATOM   4954 C CB  . SER D 4 28  A 8.684   11.581  -2.838  1.00 31.55  ? 27  SER L CB  1 
ATOM   4955 O OG  . SER D 4 28  A 8.975   10.430  -3.611  1.00 51.91  ? 27  SER L OG  1 
ATOM   4956 N N   . VAL D 4 29  B 6.241   12.687  -4.611  1.00 39.27  ? 27  VAL L N   1 
ATOM   4957 C CA  . VAL D 4 29  B 5.461   12.692  -5.843  1.00 34.89  ? 27  VAL L CA  1 
ATOM   4958 C C   . VAL D 4 29  B 6.350   13.048  -7.027  1.00 36.40  ? 27  VAL L C   1 
ATOM   4959 O O   . VAL D 4 29  B 5.890   13.644  -8.006  1.00 36.76  ? 27  VAL L O   1 
ATOM   4960 C CB  . VAL D 4 29  B 4.265   13.655  -5.737  1.00 33.44  ? 27  VAL L CB  1 
ATOM   4961 C CG1 . VAL D 4 29  B 3.221   13.091  -4.786  1.00 25.63  ? 27  VAL L CG1 1 
ATOM   4962 C CG2 . VAL D 4 29  B 4.727   15.024  -5.268  1.00 31.88  ? 27  VAL L CG2 1 
ATOM   4963 N N   . LEU D 4 30  C 7.628   12.687  -6.943  1.00 45.28  ? 27  LEU L N   1 
ATOM   4964 C CA  . LEU D 4 30  C 8.521   12.839  -8.080  1.00 42.48  ? 27  LEU L CA  1 
ATOM   4965 C C   . LEU D 4 30  C 8.231   11.767  -9.128  1.00 48.69  ? 27  LEU L C   1 
ATOM   4966 O O   . LEU D 4 30  C 7.618   10.733  -8.848  1.00 39.13  ? 27  LEU L O   1 
ATOM   4967 C CB  . LEU D 4 30  C 9.982   12.756  -7.635  1.00 36.08  ? 27  LEU L CB  1 
ATOM   4968 C CG  . LEU D 4 30  C 10.515  13.891  -6.759  1.00 45.65  ? 27  LEU L CG  1 
ATOM   4969 C CD1 . LEU D 4 30  C 11.962  13.626  -6.372  1.00 28.65  ? 27  LEU L CD1 1 
ATOM   4970 C CD2 . LEU D 4 30  C 10.388  15.226  -7.475  1.00 39.62  ? 27  LEU L CD2 1 
ATOM   4971 N N   . TYR D 4 31  D 8.678   12.028  -10.352 1.00 48.80  ? 27  TYR L N   1 
ATOM   4972 C CA  . TYR D 4 31  D 8.449   11.116  -11.467 1.00 45.42  ? 27  TYR L CA  1 
ATOM   4973 C C   . TYR D 4 31  D 9.729   10.640  -12.134 1.00 43.20  ? 27  TYR L C   1 
ATOM   4974 O O   . TYR D 4 31  D 9.832   9.461   -12.484 1.00 47.57  ? 27  TYR L O   1 
ATOM   4975 C CB  . TYR D 4 31  D 7.546   11.785  -12.516 1.00 42.38  ? 27  TYR L CB  1 
ATOM   4976 C CG  . TYR D 4 31  D 7.292   10.940  -13.745 1.00 30.46  ? 27  TYR L CG  1 
ATOM   4977 C CD1 . TYR D 4 31  D 6.353   9.919   -13.725 1.00 33.47  ? 27  TYR L CD1 1 
ATOM   4978 C CD2 . TYR D 4 31  D 7.986   11.170  -14.926 1.00 32.25  ? 27  TYR L CD2 1 
ATOM   4979 C CE1 . TYR D 4 31  D 6.116   9.145   -14.844 1.00 32.04  ? 27  TYR L CE1 1 
ATOM   4980 C CE2 . TYR D 4 31  D 7.756   10.400  -16.050 1.00 32.85  ? 27  TYR L CE2 1 
ATOM   4981 C CZ  . TYR D 4 31  D 6.820   9.390   -16.004 1.00 31.92  ? 27  TYR L CZ  1 
ATOM   4982 O OH  . TYR D 4 31  D 6.588   8.622   -17.122 1.00 36.21  ? 27  TYR L OH  1 
ATOM   4983 N N   . SER D 4 32  E 10.705  11.520  -12.324 1.00 39.74  ? 27  SER L N   1 
ATOM   4984 C CA  . SER D 4 32  E 11.940  11.166  -13.012 1.00 50.40  ? 27  SER L CA  1 
ATOM   4985 C C   . SER D 4 32  E 13.018  12.165  -12.598 1.00 66.03  ? 27  SER L C   1 
ATOM   4986 O O   . SER D 4 32  E 12.860  12.886  -11.605 1.00 62.12  ? 27  SER L O   1 
ATOM   4987 C CB  . SER D 4 32  E 11.717  11.130  -14.533 1.00 50.75  ? 27  SER L CB  1 
ATOM   4988 O OG  . SER D 4 32  E 11.380  12.414  -15.028 1.00 63.93  ? 27  SER L OG  1 
ATOM   4989 N N   . SER D 4 33  F 14.116  12.204  -13.355 1.00 75.50  ? 27  SER L N   1 
ATOM   4990 C CA  . SER D 4 33  F 15.183  13.169  -13.113 1.00 71.44  ? 27  SER L CA  1 
ATOM   4991 C C   . SER D 4 33  F 14.782  14.597  -13.459 1.00 69.28  ? 27  SER L C   1 
ATOM   4992 O O   . SER D 4 33  F 15.627  15.495  -13.366 1.00 82.45  ? 27  SER L O   1 
ATOM   4993 C CB  . SER D 4 33  F 16.432  12.777  -13.904 1.00 68.57  ? 27  SER L CB  1 
ATOM   4994 O OG  . SER D 4 33  F 16.179  12.790  -15.298 1.00 77.84  ? 27  SER L OG  1 
ATOM   4995 N N   . PHE D 4 34  ? 13.529  14.828  -13.859 1.00 70.33  ? 28  PHE L N   1 
ATOM   4996 C CA  . PHE D 4 34  ? 13.052  16.182  -14.116 1.00 70.21  ? 28  PHE L CA  1 
ATOM   4997 C C   . PHE D 4 34  ? 13.099  17.059  -12.872 1.00 64.96  ? 28  PHE L C   1 
ATOM   4998 O O   . PHE D 4 34  ? 13.134  18.288  -12.998 1.00 59.76  ? 28  PHE L O   1 
ATOM   4999 C CB  . PHE D 4 34  ? 11.625  16.136  -14.661 1.00 62.94  ? 28  PHE L CB  1 
ATOM   5000 C CG  . PHE D 4 34  ? 11.529  16.386  -16.136 1.00 66.38  ? 28  PHE L CG  1 
ATOM   5001 C CD1 . PHE D 4 34  ? 12.455  15.838  -17.009 1.00 65.49  ? 28  PHE L CD1 1 
ATOM   5002 C CD2 . PHE D 4 34  ? 10.502  17.158  -16.653 1.00 54.30  ? 28  PHE L CD2 1 
ATOM   5003 C CE1 . PHE D 4 34  ? 12.364  16.067  -18.369 1.00 62.81  ? 28  PHE L CE1 1 
ATOM   5004 C CE2 . PHE D 4 34  ? 10.404  17.388  -18.010 1.00 59.23  ? 28  PHE L CE2 1 
ATOM   5005 C CZ  . PHE D 4 34  ? 11.337  16.841  -18.870 1.00 62.28  ? 28  PHE L CZ  1 
ATOM   5006 N N   . ASN D 4 35  ? 13.099  16.453  -11.682 1.00 57.02  ? 29  ASN L N   1 
ATOM   5007 C CA  . ASN D 4 35  ? 13.117  17.183  -10.413 1.00 70.92  ? 29  ASN L CA  1 
ATOM   5008 C C   . ASN D 4 35  ? 11.927  18.136  -10.313 1.00 59.17  ? 29  ASN L C   1 
ATOM   5009 O O   . ASN D 4 35  ? 12.058  19.302  -9.934  1.00 56.29  ? 29  ASN L O   1 
ATOM   5010 C CB  . ASN D 4 35  ? 14.442  17.926  -10.224 1.00 70.30  ? 29  ASN L CB  1 
ATOM   5011 C CG  . ASN D 4 35  ? 15.636  16.995  -10.261 1.00 76.35  ? 29  ASN L CG  1 
ATOM   5012 O OD1 . ASN D 4 35  ? 15.574  15.867  -9.771  1.00 63.60  ? 29  ASN L OD1 1 
ATOM   5013 N ND2 . ASN D 4 35  ? 16.731  17.460  -10.851 1.00 83.38  ? 29  ASN L ND2 1 
ATOM   5014 N N   . LYS D 4 36  ? 10.752  17.623  -10.667 1.00 53.50  ? 30  LYS L N   1 
ATOM   5015 C CA  . LYS D 4 36  ? 9.496   18.352  -10.571 1.00 52.88  ? 30  LYS L CA  1 
ATOM   5016 C C   . LYS D 4 36  ? 8.520   17.542  -9.733  1.00 43.04  ? 30  LYS L C   1 
ATOM   5017 O O   . LYS D 4 36  ? 8.378   16.332  -9.937  1.00 45.00  ? 30  LYS L O   1 
ATOM   5018 C CB  . LYS D 4 36  ? 8.905   18.624  -11.958 1.00 48.11  ? 30  LYS L CB  1 
ATOM   5019 C CG  . LYS D 4 36  ? 9.566   19.765  -12.712 1.00 50.30  ? 30  LYS L CG  1 
ATOM   5020 C CD  . LYS D 4 36  ? 9.217   21.107  -12.090 1.00 58.64  ? 30  LYS L CD  1 
ATOM   5021 C CE  . LYS D 4 36  ? 9.758   22.260  -12.919 1.00 51.16  ? 30  LYS L CE  1 
ATOM   5022 N NZ  . LYS D 4 36  ? 9.347   23.581  -12.364 1.00 60.59  ? 30  LYS L NZ  1 
ATOM   5023 N N   . ASP D 4 37  ? 7.857   18.206  -8.790  1.00 29.85  ? 31  ASP L N   1 
ATOM   5024 C CA  . ASP D 4 37  ? 6.839   17.557  -7.974  1.00 30.23  ? 31  ASP L CA  1 
ATOM   5025 C C   . ASP D 4 37  ? 5.529   17.505  -8.753  1.00 37.57  ? 31  ASP L C   1 
ATOM   5026 O O   . ASP D 4 37  ? 4.939   18.547  -9.058  1.00 30.95  ? 31  ASP L O   1 
ATOM   5027 C CB  . ASP D 4 37  ? 6.659   18.302  -6.654  1.00 33.14  ? 31  ASP L CB  1 
ATOM   5028 C CG  . ASP D 4 37  ? 7.886   18.221  -5.769  1.00 41.89  ? 31  ASP L CG  1 
ATOM   5029 O OD1 . ASP D 4 37  ? 8.474   17.124  -5.664  1.00 47.88  ? 31  ASP L OD1 1 
ATOM   5030 O OD2 . ASP D 4 37  ? 8.266   19.254  -5.181  1.00 52.95  ? 31  ASP L OD2 1 
ATOM   5031 N N   . TYR D 4 38  ? 5.075   16.292  -9.072  1.00 26.79  ? 32  TYR L N   1 
ATOM   5032 C CA  . TYR D 4 38  ? 3.888   16.095  -9.906  1.00 20.91  ? 32  TYR L CA  1 
ATOM   5033 C C   . TYR D 4 38  ? 2.631   16.266  -9.051  1.00 22.86  ? 32  TYR L C   1 
ATOM   5034 O O   . TYR D 4 38  ? 1.906   15.322  -8.731  1.00 24.22  ? 32  TYR L O   1 
ATOM   5035 C CB  . TYR D 4 38  ? 3.943   14.736  -10.589 1.00 19.15  ? 32  TYR L CB  1 
ATOM   5036 C CG  . TYR D 4 38  ? 4.802   14.726  -11.836 1.00 25.11  ? 32  TYR L CG  1 
ATOM   5037 C CD1 . TYR D 4 38  ? 6.103   15.213  -11.811 1.00 25.23  ? 32  TYR L CD1 1 
ATOM   5038 C CD2 . TYR D 4 38  ? 4.315   14.229  -13.037 1.00 23.21  ? 32  TYR L CD2 1 
ATOM   5039 C CE1 . TYR D 4 38  ? 6.890   15.212  -12.945 1.00 27.93  ? 32  TYR L CE1 1 
ATOM   5040 C CE2 . TYR D 4 38  ? 5.095   14.222  -14.179 1.00 24.34  ? 32  TYR L CE2 1 
ATOM   5041 C CZ  . TYR D 4 38  ? 6.382   14.714  -14.126 1.00 28.13  ? 32  TYR L CZ  1 
ATOM   5042 O OH  . TYR D 4 38  ? 7.165   14.710  -15.256 1.00 34.05  ? 32  TYR L OH  1 
ATOM   5043 N N   . LEU D 4 39  ? 2.380   17.521  -8.688  1.00 29.76  ? 33  LEU L N   1 
ATOM   5044 C CA  . LEU D 4 39  ? 1.266   17.915  -7.839  1.00 17.90  ? 33  LEU L CA  1 
ATOM   5045 C C   . LEU D 4 39  ? 0.420   18.944  -8.577  1.00 31.08  ? 33  LEU L C   1 
ATOM   5046 O O   . LEU D 4 39  ? 0.951   19.792  -9.302  1.00 37.45  ? 33  LEU L O   1 
ATOM   5047 C CB  . LEU D 4 39  ? 1.781   18.488  -6.508  1.00 24.91  ? 33  LEU L CB  1 
ATOM   5048 C CG  . LEU D 4 39  ? 0.821   18.847  -5.368  1.00 28.57  ? 33  LEU L CG  1 
ATOM   5049 C CD1 . LEU D 4 39  ? 0.254   20.253  -5.525  1.00 25.62  ? 33  LEU L CD1 1 
ATOM   5050 C CD2 . LEU D 4 39  ? -0.297  17.825  -5.266  1.00 34.78  ? 33  LEU L CD2 1 
ATOM   5051 N N   . ALA D 4 40  ? -0.897  18.865  -8.396  1.00 27.03  ? 34  ALA L N   1 
ATOM   5052 C CA  . ALA D 4 40  ? -1.825  19.770  -9.058  1.00 29.86  ? 34  ALA L CA  1 
ATOM   5053 C C   . ALA D 4 40  ? -2.869  20.260  -8.066  1.00 24.08  ? 34  ALA L C   1 
ATOM   5054 O O   . ALA D 4 40  ? -3.203  19.570  -7.099  1.00 24.03  ? 34  ALA L O   1 
ATOM   5055 C CB  . ALA D 4 40  ? -2.517  19.099  -10.252 1.00 18.09  ? 34  ALA L CB  1 
ATOM   5056 N N   . TRP D 4 41  ? -3.380  21.464  -8.317  1.00 24.38  ? 35  TRP L N   1 
ATOM   5057 C CA  . TRP D 4 41  ? -4.463  22.050  -7.539  1.00 21.78  ? 35  TRP L CA  1 
ATOM   5058 C C   . TRP D 4 41  ? -5.646  22.316  -8.458  1.00 19.54  ? 35  TRP L C   1 
ATOM   5059 O O   . TRP D 4 41  ? -5.473  22.840  -9.563  1.00 20.74  ? 35  TRP L O   1 
ATOM   5060 C CB  . TRP D 4 41  ? -4.023  23.349  -6.856  1.00 16.14  ? 35  TRP L CB  1 
ATOM   5061 C CG  . TRP D 4 41  ? -3.116  23.144  -5.683  1.00 22.20  ? 35  TRP L CG  1 
ATOM   5062 C CD1 . TRP D 4 41  ? -1.754  23.212  -5.679  1.00 19.74  ? 35  TRP L CD1 1 
ATOM   5063 C CD2 . TRP D 4 41  ? -3.507  22.842  -4.337  1.00 23.43  ? 35  TRP L CD2 1 
ATOM   5064 N NE1 . TRP D 4 41  ? -1.272  22.971  -4.415  1.00 20.96  ? 35  TRP L NE1 1 
ATOM   5065 C CE2 . TRP D 4 41  ? -2.328  22.741  -3.573  1.00 23.52  ? 35  TRP L CE2 1 
ATOM   5066 C CE3 . TRP D 4 41  ? -4.739  22.649  -3.705  1.00 23.59  ? 35  TRP L CE3 1 
ATOM   5067 C CZ2 . TRP D 4 41  ? -2.344  22.453  -2.210  1.00 27.76  ? 35  TRP L CZ2 1 
ATOM   5068 C CZ3 . TRP D 4 41  ? -4.753  22.363  -2.351  1.00 22.21  ? 35  TRP L CZ3 1 
ATOM   5069 C CH2 . TRP D 4 41  ? -3.563  22.268  -1.619  1.00 27.50  ? 35  TRP L CH2 1 
ATOM   5070 N N   . TYR D 4 42  ? -6.841  21.954  -8.001  1.00 18.57  ? 36  TYR L N   1 
ATOM   5071 C CA  . TYR D 4 42  ? -8.065  22.142  -8.763  1.00 19.01  ? 36  TYR L CA  1 
ATOM   5072 C C   . TYR D 4 42  ? -9.057  22.975  -7.964  1.00 23.49  ? 36  TYR L C   1 
ATOM   5073 O O   . TYR D 4 42  ? -9.096  22.913  -6.731  1.00 20.93  ? 36  TYR L O   1 
ATOM   5074 C CB  . TYR D 4 42  ? -8.706  20.801  -9.136  1.00 15.05  ? 36  TYR L CB  1 
ATOM   5075 C CG  . TYR D 4 42  ? -7.877  19.963  -10.079 1.00 18.79  ? 36  TYR L CG  1 
ATOM   5076 C CD1 . TYR D 4 42  ? -8.020  20.085  -11.454 1.00 19.86  ? 36  TYR L CD1 1 
ATOM   5077 C CD2 . TYR D 4 42  ? -6.954  19.046  -9.595  1.00 22.71  ? 36  TYR L CD2 1 
ATOM   5078 C CE1 . TYR D 4 42  ? -7.267  19.320  -12.321 1.00 19.36  ? 36  TYR L CE1 1 
ATOM   5079 C CE2 . TYR D 4 42  ? -6.196  18.275  -10.454 1.00 21.69  ? 36  TYR L CE2 1 
ATOM   5080 C CZ  . TYR D 4 42  ? -6.357  18.417  -11.817 1.00 22.52  ? 36  TYR L CZ  1 
ATOM   5081 O OH  . TYR D 4 42  ? -5.605  17.652  -12.679 1.00 26.77  ? 36  TYR L OH  1 
ATOM   5082 N N   . GLN D 4 43  ? -9.857  23.759  -8.681  1.00 26.80  ? 37  GLN L N   1 
ATOM   5083 C CA  . GLN D 4 43  ? -10.913 24.569  -8.092  1.00 26.82  ? 37  GLN L CA  1 
ATOM   5084 C C   . GLN D 4 43  ? -12.255 24.091  -8.623  1.00 23.03  ? 37  GLN L C   1 
ATOM   5085 O O   . GLN D 4 43  ? -12.425 23.935  -9.836  1.00 24.72  ? 37  GLN L O   1 
ATOM   5086 C CB  . GLN D 4 43  ? -10.718 26.054  -8.416  1.00 22.96  ? 37  GLN L CB  1 
ATOM   5087 C CG  . GLN D 4 43  ? -11.828 26.952  -7.899  1.00 25.22  ? 37  GLN L CG  1 
ATOM   5088 C CD  . GLN D 4 43  ? -11.737 28.367  -8.438  1.00 35.89  ? 37  GLN L CD  1 
ATOM   5089 O OE1 . GLN D 4 43  ? -11.824 28.591  -9.646  1.00 28.39  ? 37  GLN L OE1 1 
ATOM   5090 N NE2 . GLN D 4 43  ? -11.562 29.333  -7.542  1.00 31.41  ? 37  GLN L NE2 1 
ATOM   5091 N N   . GLN D 4 44  ? -13.204 23.858  -7.717  1.00 20.91  ? 38  GLN L N   1 
ATOM   5092 C CA  . GLN D 4 44  ? -14.562 23.471  -8.090  1.00 29.16  ? 38  GLN L CA  1 
ATOM   5093 C C   . GLN D 4 44  ? -15.548 24.401  -7.399  1.00 24.90  ? 38  GLN L C   1 
ATOM   5094 O O   . GLN D 4 44  ? -15.800 24.264  -6.197  1.00 22.83  ? 38  GLN L O   1 
ATOM   5095 C CB  . GLN D 4 44  ? -14.855 22.014  -7.730  1.00 22.14  ? 38  GLN L CB  1 
ATOM   5096 C CG  . GLN D 4 44  ? -16.261 21.588  -8.122  1.00 25.66  ? 38  GLN L CG  1 
ATOM   5097 C CD  . GLN D 4 44  ? -16.472 20.093  -8.049  1.00 16.33  ? 38  GLN L CD  1 
ATOM   5098 O OE1 . GLN D 4 44  ? -15.983 19.427  -7.138  1.00 24.98  ? 38  GLN L OE1 1 
ATOM   5099 N NE2 . GLN D 4 44  ? -17.202 19.553  -9.018  1.00 14.54  ? 38  GLN L NE2 1 
ATOM   5100 N N   . LYS D 4 45  ? -16.101 25.337  -8.158  1.00 27.20  ? 39  LYS L N   1 
ATOM   5101 C CA  . LYS D 4 45  ? -17.137 26.225  -7.667  1.00 31.18  ? 39  LYS L CA  1 
ATOM   5102 C C   . LYS D 4 45  ? -18.466 25.479  -7.568  1.00 25.80  ? 39  LYS L C   1 
ATOM   5103 O O   . LYS D 4 45  ? -18.656 24.448  -8.219  1.00 24.97  ? 39  LYS L O   1 
ATOM   5104 C CB  . LYS D 4 45  ? -17.257 27.434  -8.590  1.00 30.16  ? 39  LYS L CB  1 
ATOM   5105 C CG  . LYS D 4 45  ? -15.946 28.183  -8.768  1.00 28.71  ? 39  LYS L CG  1 
ATOM   5106 C CD  . LYS D 4 45  ? -16.102 29.391  -9.672  1.00 39.69  ? 39  LYS L CD  1 
ATOM   5107 C CE  . LYS D 4 45  ? -14.809 30.188  -9.740  1.00 46.36  ? 39  LYS L CE  1 
ATOM   5108 N NZ  . LYS D 4 45  ? -14.941 31.399  -10.595 1.00 57.12  ? 39  LYS L NZ  1 
ATOM   5109 N N   . PRO D 4 46  ? -19.396 25.966  -6.742  1.00 33.04  ? 40  PRO L N   1 
ATOM   5110 C CA  . PRO D 4 46  ? -20.681 25.266  -6.574  1.00 35.82  ? 40  PRO L CA  1 
ATOM   5111 C C   . PRO D 4 46  ? -21.399 25.069  -7.900  1.00 32.58  ? 40  PRO L C   1 
ATOM   5112 O O   . PRO D 4 46  ? -21.665 26.025  -8.634  1.00 33.06  ? 40  PRO L O   1 
ATOM   5113 C CB  . PRO D 4 46  ? -21.465 26.193  -5.639  1.00 24.66  ? 40  PRO L CB  1 
ATOM   5114 C CG  . PRO D 4 46  ? -20.421 26.930  -4.880  1.00 25.48  ? 40  PRO L CG  1 
ATOM   5115 C CD  . PRO D 4 46  ? -19.281 27.127  -5.839  1.00 26.40  ? 40  PRO L CD  1 
ATOM   5116 N N   . GLY D 4 47  ? -21.710 23.811  -8.205  1.00 27.47  ? 41  GLY L N   1 
ATOM   5117 C CA  . GLY D 4 47  ? -22.413 23.472  -9.426  1.00 21.30  ? 41  GLY L CA  1 
ATOM   5118 C C   . GLY D 4 47  ? -21.568 23.452  -10.679 1.00 39.34  ? 41  GLY L C   1 
ATOM   5119 O O   . GLY D 4 47  ? -22.118 23.270  -11.770 1.00 41.62  ? 41  GLY L O   1 
ATOM   5120 N N   . GLN D 4 48  ? -20.253 23.623  -10.563 1.00 30.30  ? 42  GLN L N   1 
ATOM   5121 C CA  . GLN D 4 48  ? -19.381 23.706  -11.723 1.00 28.11  ? 42  GLN L CA  1 
ATOM   5122 C C   . GLN D 4 48  ? -18.407 22.535  -11.752 1.00 26.73  ? 42  GLN L C   1 
ATOM   5123 O O   . GLN D 4 48  ? -18.102 21.950  -10.708 1.00 29.47  ? 42  GLN L O   1 
ATOM   5124 C CB  . GLN D 4 48  ? -18.592 25.021  -11.721 1.00 32.00  ? 42  GLN L CB  1 
ATOM   5125 C CG  . GLN D 4 48  ? -19.460 26.256  -11.588 1.00 36.78  ? 42  GLN L CG  1 
ATOM   5126 C CD  . GLN D 4 48  ? -20.521 26.333  -12.664 1.00 56.63  ? 42  GLN L CD  1 
ATOM   5127 O OE1 . GLN D 4 48  ? -20.213 26.353  -13.856 1.00 51.64  ? 42  GLN L OE1 1 
ATOM   5128 N NE2 . GLN D 4 48  ? -21.782 26.365  -12.249 1.00 51.22  ? 42  GLN L NE2 1 
ATOM   5129 N N   . PRO D 4 49  ? -17.910 22.165  -12.929 1.00 26.30  ? 43  PRO L N   1 
ATOM   5130 C CA  . PRO D 4 49  ? -16.868 21.135  -13.007 1.00 26.64  ? 43  PRO L CA  1 
ATOM   5131 C C   . PRO D 4 49  ? -15.562 21.640  -12.421 1.00 27.70  ? 43  PRO L C   1 
ATOM   5132 O O   . PRO D 4 49  ? -15.359 22.858  -12.294 1.00 26.09  ? 43  PRO L O   1 
ATOM   5133 C CB  . PRO D 4 49  ? -16.737 20.875  -14.517 1.00 17.86  ? 43  PRO L CB  1 
ATOM   5134 C CG  . PRO D 4 49  ? -18.008 21.385  -15.111 1.00 25.51  ? 43  PRO L CG  1 
ATOM   5135 C CD  . PRO D 4 49  ? -18.401 22.551  -14.261 1.00 29.54  ? 43  PRO L CD  1 
ATOM   5136 N N   . PRO D 4 50  ? -14.659 20.740  -12.035 1.00 29.39  ? 44  PRO L N   1 
ATOM   5137 C CA  . PRO D 4 50  ? -13.358 21.181  -11.520 1.00 20.14  ? 44  PRO L CA  1 
ATOM   5138 C C   . PRO D 4 50  ? -12.569 21.937  -12.580 1.00 27.32  ? 44  PRO L C   1 
ATOM   5139 O O   . PRO D 4 50  ? -12.682 21.674  -13.779 1.00 21.85  ? 44  PRO L O   1 
ATOM   5140 C CB  . PRO D 4 50  ? -12.662 19.869  -11.136 1.00 16.05  ? 44  PRO L CB  1 
ATOM   5141 C CG  . PRO D 4 50  ? -13.770 18.881  -10.967 1.00 17.49  ? 44  PRO L CG  1 
ATOM   5142 C CD  . PRO D 4 50  ? -14.814 19.277  -11.965 1.00 21.60  ? 44  PRO L CD  1 
ATOM   5143 N N   . LYS D 4 51  ? -11.765 22.891  -12.117 1.00 24.15  ? 45  LYS L N   1 
ATOM   5144 C CA  . LYS D 4 51  ? -10.941 23.721  -12.985 1.00 28.50  ? 45  LYS L CA  1 
ATOM   5145 C C   . LYS D 4 51  ? -9.497  23.649  -12.514 1.00 22.45  ? 45  LYS L C   1 
ATOM   5146 O O   . LYS D 4 51  ? -9.213  23.895  -11.338 1.00 23.91  ? 45  LYS L O   1 
ATOM   5147 C CB  . LYS D 4 51  ? -11.438 25.170  -12.986 1.00 33.29  ? 45  LYS L CB  1 
ATOM   5148 C CG  . LYS D 4 51  ? -10.508 26.166  -13.658 1.00 33.73  ? 45  LYS L CG  1 
ATOM   5149 C CD  . LYS D 4 51  ? -11.026 27.585  -13.477 1.00 36.39  ? 45  LYS L CD  1 
ATOM   5150 C CE  . LYS D 4 51  ? -10.043 28.617  -14.004 1.00 43.03  ? 45  LYS L CE  1 
ATOM   5151 N NZ  . LYS D 4 51  ? -10.500 30.007  -13.721 1.00 53.88  ? 45  LYS L NZ  1 
ATOM   5152 N N   . LEU D 4 52  ? -8.591  23.311  -13.429 1.00 15.51  ? 46  LEU L N   1 
ATOM   5153 C CA  . LEU D 4 52  ? -7.181  23.206  -13.077 1.00 21.25  ? 46  LEU L CA  1 
ATOM   5154 C C   . LEU D 4 52  ? -6.583  24.592  -12.877 1.00 27.19  ? 46  LEU L C   1 
ATOM   5155 O O   . LEU D 4 52  ? -6.697  25.463  -13.745 1.00 32.25  ? 46  LEU L O   1 
ATOM   5156 C CB  . LEU D 4 52  ? -6.416  22.451  -14.162 1.00 23.18  ? 46  LEU L CB  1 
ATOM   5157 C CG  . LEU D 4 52  ? -4.894  22.399  -13.994 1.00 25.73  ? 46  LEU L CG  1 
ATOM   5158 C CD1 . LEU D 4 52  ? -4.511  21.674  -12.712 1.00 25.37  ? 46  LEU L CD1 1 
ATOM   5159 C CD2 . LEU D 4 52  ? -4.236  21.747  -15.201 1.00 24.28  ? 46  LEU L CD2 1 
ATOM   5160 N N   . LEU D 4 53  ? -5.940  24.795  -11.729 1.00 26.38  ? 47  LEU L N   1 
ATOM   5161 C CA  . LEU D 4 53  ? -5.316  26.070  -11.400 1.00 31.11  ? 47  LEU L CA  1 
ATOM   5162 C C   . LEU D 4 53  ? -3.799  26.031  -11.528 1.00 35.84  ? 47  LEU L C   1 
ATOM   5163 O O   . LEU D 4 53  ? -3.211  26.868  -12.218 1.00 33.83  ? 47  LEU L O   1 
ATOM   5164 C CB  . LEU D 4 53  ? -5.698  26.494  -9.977  1.00 29.85  ? 47  LEU L CB  1 
ATOM   5165 C CG  . LEU D 4 53  ? -7.170  26.786  -9.695  1.00 40.31  ? 47  LEU L CG  1 
ATOM   5166 C CD1 . LEU D 4 53  ? -7.339  27.202  -8.245  1.00 31.45  ? 47  LEU L CD1 1 
ATOM   5167 C CD2 . LEU D 4 53  ? -7.694  27.863  -10.633 1.00 35.00  ? 47  LEU L CD2 1 
ATOM   5168 N N   . ILE D 4 54  ? -3.153  25.074  -10.867 1.00 30.69  ? 48  ILE L N   1 
ATOM   5169 C CA  . ILE D 4 54  ? -1.700  25.020  -10.774 1.00 30.67  ? 48  ILE L CA  1 
ATOM   5170 C C   . ILE D 4 54  ? -1.242  23.586  -10.997 1.00 30.05  ? 48  ILE L C   1 
ATOM   5171 O O   . ILE D 4 54  ? -1.827  22.644  -10.452 1.00 34.13  ? 48  ILE L O   1 
ATOM   5172 C CB  . ILE D 4 54  ? -1.211  25.552  -9.410  1.00 32.82  ? 48  ILE L CB  1 
ATOM   5173 C CG1 . ILE D 4 54  ? -1.492  27.052  -9.293  1.00 34.44  ? 48  ILE L CG1 1 
ATOM   5174 C CG2 . ILE D 4 54  ? 0.268   25.259  -9.211  1.00 29.94  ? 48  ILE L CG2 1 
ATOM   5175 C CD1 . ILE D 4 54  ? -1.301  27.598  -7.904  1.00 40.64  ? 48  ILE L CD1 1 
ATOM   5176 N N   . TYR D 4 55  ? -0.198  23.424  -11.804 1.00 28.69  ? 49  TYR L N   1 
ATOM   5177 C CA  . TYR D 4 55  ? 0.434   22.135  -12.039 1.00 33.03  ? 49  TYR L CA  1 
ATOM   5178 C C   . TYR D 4 55  ? 1.920   22.232  -11.715 1.00 29.51  ? 49  TYR L C   1 
ATOM   5179 O O   . TYR D 4 55  ? 2.512   23.314  -11.733 1.00 33.68  ? 49  TYR L O   1 
ATOM   5180 C CB  . TYR D 4 55  ? 0.232   21.664  -13.485 1.00 33.88  ? 49  TYR L CB  1 
ATOM   5181 C CG  . TYR D 4 55  ? 0.848   22.569  -14.525 1.00 41.68  ? 49  TYR L CG  1 
ATOM   5182 C CD1 . TYR D 4 55  ? 0.179   23.701  -14.973 1.00 40.55  ? 49  TYR L CD1 1 
ATOM   5183 C CD2 . TYR D 4 55  ? 2.094   22.286  -15.069 1.00 30.28  ? 49  TYR L CD2 1 
ATOM   5184 C CE1 . TYR D 4 55  ? 0.738   24.530  -15.927 1.00 50.69  ? 49  TYR L CE1 1 
ATOM   5185 C CE2 . TYR D 4 55  ? 2.661   23.108  -16.024 1.00 39.78  ? 49  TYR L CE2 1 
ATOM   5186 C CZ  . TYR D 4 55  ? 1.978   24.228  -16.451 1.00 42.44  ? 49  TYR L CZ  1 
ATOM   5187 O OH  . TYR D 4 55  ? 2.542   25.050  -17.400 1.00 53.14  ? 49  TYR L OH  1 
ATOM   5188 N N   . TRP D 4 56  ? 2.513   21.077  -11.404 1.00 27.70  ? 50  TRP L N   1 
ATOM   5189 C CA  . TRP D 4 56  ? 3.894   20.988  -10.923 1.00 32.35  ? 50  TRP L CA  1 
ATOM   5190 C C   . TRP D 4 56  ? 4.101   21.821  -9.661  1.00 32.66  ? 50  TRP L C   1 
ATOM   5191 O O   . TRP D 4 56  ? 5.204   22.309  -9.390  1.00 37.55  ? 50  TRP L O   1 
ATOM   5192 C CB  . TRP D 4 56  ? 4.892   21.375  -12.017 1.00 29.82  ? 50  TRP L CB  1 
ATOM   5193 C CG  . TRP D 4 56  ? 5.240   20.219  -12.909 1.00 37.41  ? 50  TRP L CG  1 
ATOM   5194 C CD1 . TRP D 4 56  ? 5.109   18.891  -12.616 1.00 38.10  ? 50  TRP L CD1 1 
ATOM   5195 C CD2 . TRP D 4 56  ? 5.768   20.286  -14.237 1.00 36.27  ? 50  TRP L CD2 1 
ATOM   5196 N NE1 . TRP D 4 56  ? 5.528   18.129  -13.680 1.00 33.67  ? 50  TRP L NE1 1 
ATOM   5197 C CE2 . TRP D 4 56  ? 5.937   18.961  -14.688 1.00 39.44  ? 50  TRP L CE2 1 
ATOM   5198 C CE3 . TRP D 4 56  ? 6.116   21.338  -15.089 1.00 43.06  ? 50  TRP L CE3 1 
ATOM   5199 C CZ2 . TRP D 4 56  ? 6.439   18.661  -15.952 1.00 46.81  ? 50  TRP L CZ2 1 
ATOM   5200 C CZ3 . TRP D 4 56  ? 6.613   21.039  -16.342 1.00 44.42  ? 50  TRP L CZ3 1 
ATOM   5201 C CH2 . TRP D 4 56  ? 6.770   19.712  -16.762 1.00 50.32  ? 50  TRP L CH2 1 
ATOM   5202 N N   . ALA D 4 57  ? 3.008   22.005  -8.919  1.00 28.25  ? 51  ALA L N   1 
ATOM   5203 C CA  . ALA D 4 57  ? 2.943   22.530  -7.558  1.00 32.43  ? 51  ALA L CA  1 
ATOM   5204 C C   . ALA D 4 57  ? 3.219   24.025  -7.464  1.00 31.26  ? 51  ALA L C   1 
ATOM   5205 O O   . ALA D 4 57  ? 2.983   24.628  -6.412  1.00 34.80  ? 51  ALA L O   1 
ATOM   5206 C CB  . ALA D 4 57  ? 3.907   21.763  -6.641  1.00 28.11  ? 51  ALA L CB  1 
ATOM   5207 N N   . SER D 4 58  ? 3.693   24.644  -8.552  1.00 34.27  ? 52  SER L N   1 
ATOM   5208 C CA  . SER D 4 58  ? 3.920   26.094  -8.561  1.00 32.29  ? 52  SER L CA  1 
ATOM   5209 C C   . SER D 4 58  ? 3.548   26.794  -9.860  1.00 33.54  ? 52  SER L C   1 
ATOM   5210 O O   . SER D 4 58  ? 3.422   28.023  -9.849  1.00 33.31  ? 52  SER L O   1 
ATOM   5211 C CB  . SER D 4 58  ? 5.385   26.404  -8.234  1.00 22.35  ? 52  SER L CB  1 
ATOM   5212 O OG  . SER D 4 58  ? 6.268   25.569  -8.965  1.00 49.44  ? 52  SER L OG  1 
ATOM   5213 N N   . ILE D 4 59  ? 3.369   26.088  -10.973 1.00 26.93  ? 53  ILE L N   1 
ATOM   5214 C CA  . ILE D 4 59  ? 3.155   26.731  -12.266 1.00 31.79  ? 53  ILE L CA  1 
ATOM   5215 C C   . ILE D 4 59  ? 1.655   26.899  -12.475 1.00 31.36  ? 53  ILE L C   1 
ATOM   5216 O O   . ILE D 4 59  ? 0.935   25.916  -12.668 1.00 39.64  ? 53  ILE L O   1 
ATOM   5217 C CB  . ILE D 4 59  ? 3.789   25.928  -13.408 1.00 33.76  ? 53  ILE L CB  1 
ATOM   5218 C CG1 . ILE D 4 59  ? 5.277   25.686  -13.116 1.00 30.26  ? 53  ILE L CG1 1 
ATOM   5219 C CG2 . ILE D 4 59  ? 3.617   26.648  -14.754 1.00 32.81  ? 53  ILE L CG2 1 
ATOM   5220 C CD1 . ILE D 4 59  ? 5.963   24.832  -14.146 1.00 40.72  ? 53  ILE L CD1 1 
ATOM   5221 N N   . ARG D 4 60  ? 1.177   28.143  -12.437 1.00 36.55  ? 54  ARG L N   1 
ATOM   5222 C CA  . ARG D 4 60  ? -0.234  28.391  -12.696 1.00 42.40  ? 54  ARG L CA  1 
ATOM   5223 C C   . ARG D 4 60  ? -0.529  28.245  -14.184 1.00 36.69  ? 54  ARG L C   1 
ATOM   5224 O O   . ARG D 4 60  ? 0.305   28.558  -15.038 1.00 33.18  ? 54  ARG L O   1 
ATOM   5225 C CB  . ARG D 4 60  ? -0.636  29.779  -12.196 1.00 28.59  ? 54  ARG L CB  1 
ATOM   5226 C CG  . ARG D 4 60  ? 0.258   30.906  -12.681 1.00 50.63  ? 54  ARG L CG  1 
ATOM   5227 C CD  . ARG D 4 60  ? 0.149   32.134  -11.783 1.00 32.21  ? 54  ARG L CD  1 
ATOM   5228 N NE  . ARG D 4 60  ? 1.239   32.214  -10.816 1.00 45.36  ? 54  ARG L NE  1 
ATOM   5229 C CZ  . ARG D 4 60  ? 1.248   33.019  -9.762  1.00 51.25  ? 54  ARG L CZ  1 
ATOM   5230 N NH1 . ARG D 4 60  ? 0.224   33.809  -9.486  1.00 53.33  ? 54  ARG L NH1 1 
ATOM   5231 N NH2 . ARG D 4 60  ? 2.307   33.025  -8.958  1.00 50.09  ? 54  ARG L NH2 1 
ATOM   5232 N N   . GLU D 4 61  ? -1.720  27.736  -14.487 1.00 38.10  ? 55  GLU L N   1 
ATOM   5233 C CA  . GLU D 4 61  ? -2.123  27.521  -15.866 1.00 43.77  ? 55  GLU L CA  1 
ATOM   5234 C C   . GLU D 4 61  ? -2.564  28.833  -16.508 1.00 43.43  ? 55  GLU L C   1 
ATOM   5235 O O   . GLU D 4 61  ? -2.794  29.841  -15.834 1.00 46.91  ? 55  GLU L O   1 
ATOM   5236 C CB  . GLU D 4 61  ? -3.245  26.490  -15.947 1.00 37.66  ? 55  GLU L CB  1 
ATOM   5237 C CG  . GLU D 4 61  ? -2.843  25.203  -16.637 1.00 45.65  ? 55  GLU L CG  1 
ATOM   5238 C CD  . GLU D 4 61  ? -3.834  24.786  -17.705 1.00 47.97  ? 55  GLU L CD  1 
ATOM   5239 O OE1 . GLU D 4 61  ? -4.975  25.291  -17.686 1.00 53.40  ? 55  GLU L OE1 1 
ATOM   5240 O OE2 . GLU D 4 61  ? -3.469  23.959  -18.565 1.00 61.19  ? 55  GLU L OE2 1 
ATOM   5241 N N   . SER D 4 62  ? -2.679  28.807  -17.836 1.00 48.51  ? 56  SER L N   1 
ATOM   5242 C CA  . SER D 4 62  ? -3.063  29.995  -18.586 1.00 57.36  ? 56  SER L CA  1 
ATOM   5243 C C   . SER D 4 62  ? -4.463  30.448  -18.191 1.00 49.03  ? 56  SER L C   1 
ATOM   5244 O O   . SER D 4 62  ? -5.391  29.639  -18.096 1.00 53.99  ? 56  SER L O   1 
ATOM   5245 C CB  . SER D 4 62  ? -2.996  29.713  -20.087 1.00 50.55  ? 56  SER L CB  1 
ATOM   5246 O OG  . SER D 4 62  ? -3.841  28.632  -20.441 1.00 64.40  ? 56  SER L OG  1 
ATOM   5247 N N   . GLY D 4 63  ? -4.609  31.751  -17.951 1.00 38.56  ? 57  GLY L N   1 
ATOM   5248 C CA  . GLY D 4 63  ? -5.862  32.329  -17.533 1.00 35.60  ? 57  GLY L CA  1 
ATOM   5249 C C   . GLY D 4 63  ? -6.058  32.411  -16.034 1.00 43.27  ? 57  GLY L C   1 
ATOM   5250 O O   . GLY D 4 63  ? -6.934  33.154  -15.578 1.00 40.21  ? 57  GLY L O   1 
ATOM   5251 N N   . VAL D 4 64  ? -5.272  31.675  -15.260 1.00 40.99  ? 58  VAL L N   1 
ATOM   5252 C CA  . VAL D 4 64  ? -5.403  31.716  -13.799 1.00 47.47  ? 58  VAL L CA  1 
ATOM   5253 C C   . VAL D 4 64  ? -4.857  33.045  -13.286 1.00 42.36  ? 58  VAL L C   1 
ATOM   5254 O O   . VAL D 4 64  ? -3.743  33.443  -13.672 1.00 41.60  ? 58  VAL L O   1 
ATOM   5255 C CB  . VAL D 4 64  ? -4.666  30.534  -13.166 1.00 37.27  ? 58  VAL L CB  1 
ATOM   5256 C CG1 . VAL D 4 64  ? -4.770  30.590  -11.650 1.00 31.85  ? 58  VAL L CG1 1 
ATOM   5257 C CG2 . VAL D 4 64  ? -5.226  29.221  -13.693 1.00 34.79  ? 58  VAL L CG2 1 
ATOM   5258 N N   . PRO D 4 65  ? -5.591  33.763  -12.438 1.00 44.71  ? 59  PRO L N   1 
ATOM   5259 C CA  . PRO D 4 65  ? -5.112  35.061  -11.946 1.00 40.26  ? 59  PRO L CA  1 
ATOM   5260 C C   . PRO D 4 65  ? -3.815  34.930  -11.159 1.00 45.03  ? 59  PRO L C   1 
ATOM   5261 O O   . PRO D 4 65  ? -3.385  33.844  -10.768 1.00 46.57  ? 59  PRO L O   1 
ATOM   5262 C CB  . PRO D 4 65  ? -6.259  35.550  -11.055 1.00 43.34  ? 59  PRO L CB  1 
ATOM   5263 C CG  . PRO D 4 65  ? -7.464  34.836  -11.571 1.00 41.88  ? 59  PRO L CG  1 
ATOM   5264 C CD  . PRO D 4 65  ? -6.975  33.489  -12.015 1.00 42.47  ? 59  PRO L CD  1 
ATOM   5265 N N   . ASP D 4 66  ? -3.186  36.084  -10.927 1.00 57.20  ? 60  ASP L N   1 
ATOM   5266 C CA  . ASP D 4 66  ? -1.889  36.122  -10.262 1.00 44.92  ? 60  ASP L CA  1 
ATOM   5267 C C   . ASP D 4 66  ? -1.982  35.914  -8.756  1.00 41.48  ? 60  ASP L C   1 
ATOM   5268 O O   . ASP D 4 66  ? -0.960  35.636  -8.121  1.00 44.55  ? 60  ASP L O   1 
ATOM   5269 C CB  . ASP D 4 66  ? -1.187  37.449  -10.556 1.00 61.26  ? 60  ASP L CB  1 
ATOM   5270 C CG  . ASP D 4 66  ? -0.764  37.573  -12.006 1.00 74.39  ? 60  ASP L CG  1 
ATOM   5271 O OD1 . ASP D 4 66  ? -0.275  36.571  -12.571 1.00 70.47  ? 60  ASP L OD1 1 
ATOM   5272 O OD2 . ASP D 4 66  ? -0.923  38.670  -12.582 1.00 69.42  ? 60  ASP L OD2 1 
ATOM   5273 N N   . ARG D 4 67  ? -3.174  36.039  -8.169  1.00 41.18  ? 61  ARG L N   1 
ATOM   5274 C CA  . ARG D 4 67  ? -3.322  35.811  -6.737  1.00 43.29  ? 61  ARG L CA  1 
ATOM   5275 C C   . ARG D 4 67  ? -3.232  34.337  -6.363  1.00 49.96  ? 61  ARG L C   1 
ATOM   5276 O O   . ARG D 4 67  ? -3.100  34.027  -5.174  1.00 42.25  ? 61  ARG L O   1 
ATOM   5277 C CB  . ARG D 4 67  ? -4.650  36.391  -6.250  1.00 44.33  ? 61  ARG L CB  1 
ATOM   5278 C CG  . ARG D 4 67  ? -5.863  35.849  -6.982  1.00 48.54  ? 61  ARG L CG  1 
ATOM   5279 C CD  . ARG D 4 67  ? -7.130  36.559  -6.547  1.00 37.69  ? 61  ARG L CD  1 
ATOM   5280 N NE  . ARG D 4 67  ? -8.314  36.014  -7.199  1.00 43.71  ? 61  ARG L NE  1 
ATOM   5281 C CZ  . ARG D 4 67  ? -8.787  36.436  -8.363  1.00 47.58  ? 61  ARG L CZ  1 
ATOM   5282 N NH1 . ARG D 4 67  ? -8.201  37.414  -9.033  1.00 45.02  ? 61  ARG L NH1 1 
ATOM   5283 N NH2 . ARG D 4 67  ? -9.875  35.861  -8.868  1.00 37.45  ? 61  ARG L NH2 1 
ATOM   5284 N N   . PHE D 4 68  ? -3.301  33.432  -7.336  1.00 34.08  ? 62  PHE L N   1 
ATOM   5285 C CA  . PHE D 4 68  ? -3.149  32.003  -7.093  1.00 41.37  ? 62  PHE L CA  1 
ATOM   5286 C C   . PHE D 4 68  ? -1.673  31.632  -7.185  1.00 44.65  ? 62  PHE L C   1 
ATOM   5287 O O   . PHE D 4 68  ? -1.056  31.783  -8.245  1.00 41.70  ? 62  PHE L O   1 
ATOM   5288 C CB  . PHE D 4 68  ? -3.960  31.194  -8.105  1.00 49.59  ? 62  PHE L CB  1 
ATOM   5289 C CG  . PHE D 4 68  ? -5.445  31.284  -7.912  1.00 40.72  ? 62  PHE L CG  1 
ATOM   5290 C CD1 . PHE D 4 68  ? -6.113  30.344  -7.136  1.00 43.12  ? 62  PHE L CD1 1 
ATOM   5291 C CD2 . PHE D 4 68  ? -6.176  32.293  -8.530  1.00 43.22  ? 62  PHE L CD2 1 
ATOM   5292 C CE1 . PHE D 4 68  ? -7.487  30.415  -6.961  1.00 45.82  ? 62  PHE L CE1 1 
ATOM   5293 C CE2 . PHE D 4 68  ? -7.544  32.378  -8.368  1.00 41.53  ? 62  PHE L CE2 1 
ATOM   5294 C CZ  . PHE D 4 68  ? -8.206  31.436  -7.578  1.00 43.82  ? 62  PHE L CZ  1 
ATOM   5295 N N   . SER D 4 69  ? -1.106  31.152  -6.080  1.00 41.03  ? 63  SER L N   1 
ATOM   5296 C CA  . SER D 4 69  ? 0.284   30.719  -6.060  1.00 44.21  ? 63  SER L CA  1 
ATOM   5297 C C   . SER D 4 69  ? 0.390   29.389  -5.330  1.00 39.22  ? 63  SER L C   1 
ATOM   5298 O O   . SER D 4 69  ? -0.281  29.170  -4.318  1.00 36.13  ? 63  SER L O   1 
ATOM   5299 C CB  . SER D 4 69  ? 1.191   31.759  -5.389  1.00 30.95  ? 63  SER L CB  1 
ATOM   5300 O OG  . SER D 4 69  ? 0.810   31.970  -4.042  1.00 47.44  ? 63  SER L OG  1 
ATOM   5301 N N   . GLY D 4 70  ? 1.231   28.509  -5.853  1.00 35.92  ? 64  GLY L N   1 
ATOM   5302 C CA  . GLY D 4 70  ? 1.490   27.217  -5.235  1.00 35.98  ? 64  GLY L CA  1 
ATOM   5303 C C   . GLY D 4 70  ? 2.944   27.104  -4.821  1.00 30.91  ? 64  GLY L C   1 
ATOM   5304 O O   . GLY D 4 70  ? 3.838   27.558  -5.538  1.00 37.09  ? 64  GLY L O   1 
ATOM   5305 N N   . SER D 4 71  ? 3.174   26.487  -3.663  1.00 32.53  ? 65  SER L N   1 
ATOM   5306 C CA  . SER D 4 71  ? 4.510   26.362  -3.099  1.00 34.18  ? 65  SER L CA  1 
ATOM   5307 C C   . SER D 4 71  ? 4.654   24.989  -2.457  1.00 39.71  ? 65  SER L C   1 
ATOM   5308 O O   . SER D 4 71  ? 3.711   24.192  -2.422  1.00 38.69  ? 65  SER L O   1 
ATOM   5309 C CB  . SER D 4 71  ? 4.787   27.476  -2.082  1.00 32.91  ? 65  SER L CB  1 
ATOM   5310 O OG  . SER D 4 71  ? 3.870   27.417  -1.003  1.00 34.89  ? 65  SER L OG  1 
ATOM   5311 N N   . GLY D 4 72  ? 5.849   24.715  -1.948  1.00 38.92  ? 66  GLY L N   1 
ATOM   5312 C CA  . GLY D 4 72  ? 6.129   23.475  -1.258  1.00 28.34  ? 66  GLY L CA  1 
ATOM   5313 C C   . GLY D 4 72  ? 6.858   22.473  -2.139  1.00 37.99  ? 66  GLY L C   1 
ATOM   5314 O O   . GLY D 4 72  ? 6.880   22.571  -3.369  1.00 32.00  ? 66  GLY L O   1 
ATOM   5315 N N   . SER D 4 73  ? 7.463   21.485  -1.485  1.00 42.21  ? 67  SER L N   1 
ATOM   5316 C CA  . SER D 4 73  ? 8.220   20.451  -2.175  1.00 42.21  ? 67  SER L CA  1 
ATOM   5317 C C   . SER D 4 73  ? 8.244   19.203  -1.306  1.00 36.23  ? 67  SER L C   1 
ATOM   5318 O O   . SER D 4 73  ? 7.927   19.243  -0.114  1.00 35.07  ? 67  SER L O   1 
ATOM   5319 C CB  . SER D 4 73  ? 9.641   20.921  -2.504  1.00 48.11  ? 67  SER L CB  1 
ATOM   5320 O OG  . SER D 4 73  ? 10.351  21.257  -1.324  1.00 48.10  ? 67  SER L OG  1 
ATOM   5321 N N   . GLY D 4 74  ? 8.618   18.084  -1.920  1.00 42.62  ? 68  GLY L N   1 
ATOM   5322 C CA  . GLY D 4 74  ? 8.700   16.835  -1.190  1.00 31.52  ? 68  GLY L CA  1 
ATOM   5323 C C   . GLY D 4 74  ? 7.337   16.228  -0.937  1.00 39.40  ? 68  GLY L C   1 
ATOM   5324 O O   . GLY D 4 74  ? 6.712   15.678  -1.848  1.00 26.52  ? 68  GLY L O   1 
ATOM   5325 N N   . THR D 4 75  ? 6.872   16.316  0.309   1.00 37.18  ? 69  THR L N   1 
ATOM   5326 C CA  . THR D 4 75  ? 5.556   15.824  0.687   1.00 32.87  ? 69  THR L CA  1 
ATOM   5327 C C   . THR D 4 75  ? 4.642   16.912  1.234   1.00 36.52  ? 69  THR L C   1 
ATOM   5328 O O   . THR D 4 75  ? 3.488   16.617  1.568   1.00 43.29  ? 69  THR L O   1 
ATOM   5329 C CB  . THR D 4 75  ? 5.687   14.701  1.725   1.00 40.73  ? 69  THR L CB  1 
ATOM   5330 O OG1 . THR D 4 75  ? 6.359   15.198  2.889   1.00 46.91  ? 69  THR L OG1 1 
ATOM   5331 C CG2 . THR D 4 75  ? 6.474   13.532  1.150   1.00 30.43  ? 69  THR L CG2 1 
ATOM   5332 N N   . ASP D 4 76  ? 5.115   18.152  1.337   1.00 37.15  ? 70  ASP L N   1 
ATOM   5333 C CA  . ASP D 4 76  ? 4.326   19.264  1.855   1.00 39.95  ? 70  ASP L CA  1 
ATOM   5334 C C   . ASP D 4 76  ? 4.124   20.288  0.749   1.00 37.14  ? 70  ASP L C   1 
ATOM   5335 O O   . ASP D 4 76  ? 5.097   20.768  0.159   1.00 39.60  ? 70  ASP L O   1 
ATOM   5336 C CB  . ASP D 4 76  ? 5.009   19.908  3.063   1.00 42.15  ? 70  ASP L CB  1 
ATOM   5337 C CG  . ASP D 4 76  ? 4.852   19.088  4.325   1.00 49.88  ? 70  ASP L CG  1 
ATOM   5338 O OD1 . ASP D 4 76  ? 3.707   18.702  4.644   1.00 58.45  ? 70  ASP L OD1 1 
ATOM   5339 O OD2 . ASP D 4 76  ? 5.872   18.821  4.993   1.00 69.12  ? 70  ASP L OD2 1 
ATOM   5340 N N   . PHE D 4 77  ? 2.865   20.625  0.477   1.00 32.76  ? 71  PHE L N   1 
ATOM   5341 C CA  . PHE D 4 77  ? 2.524   21.584  -0.563  1.00 34.13  ? 71  PHE L CA  1 
ATOM   5342 C C   . PHE D 4 77  ? 1.444   22.522  -0.047  1.00 28.83  ? 71  PHE L C   1 
ATOM   5343 O O   . PHE D 4 77  ? 0.632   22.150  0.805   1.00 30.45  ? 71  PHE L O   1 
ATOM   5344 C CB  . PHE D 4 77  ? 2.055   20.878  -1.840  1.00 29.95  ? 71  PHE L CB  1 
ATOM   5345 C CG  . PHE D 4 77  ? 3.045   19.886  -2.376  1.00 36.43  ? 71  PHE L CG  1 
ATOM   5346 C CD1 . PHE D 4 77  ? 4.107   20.304  -3.160  1.00 35.44  ? 71  PHE L CD1 1 
ATOM   5347 C CD2 . PHE D 4 77  ? 2.918   18.537  -2.092  1.00 36.21  ? 71  PHE L CD2 1 
ATOM   5348 C CE1 . PHE D 4 77  ? 5.022   19.395  -3.653  1.00 33.77  ? 71  PHE L CE1 1 
ATOM   5349 C CE2 . PHE D 4 77  ? 3.830   17.623  -2.583  1.00 32.28  ? 71  PHE L CE2 1 
ATOM   5350 C CZ  . PHE D 4 77  ? 4.883   18.053  -3.365  1.00 33.14  ? 71  PHE L CZ  1 
ATOM   5351 N N   . THR D 4 78  ? 1.439   23.745  -0.574  1.00 32.98  ? 72  THR L N   1 
ATOM   5352 C CA  . THR D 4 78  ? 0.541   24.786  -0.099  1.00 35.54  ? 72  THR L CA  1 
ATOM   5353 C C   . THR D 4 78  ? -0.026  25.566  -1.276  1.00 38.21  ? 72  THR L C   1 
ATOM   5354 O O   . THR D 4 78  ? 0.701   25.907  -2.213  1.00 28.42  ? 72  THR L O   1 
ATOM   5355 C CB  . THR D 4 78  ? 1.262   25.747  0.859   1.00 35.38  ? 72  THR L CB  1 
ATOM   5356 O OG1 . THR D 4 78  ? 1.824   25.006  1.949   1.00 33.86  ? 72  THR L OG1 1 
ATOM   5357 C CG2 . THR D 4 78  ? 0.296   26.789  1.406   1.00 32.55  ? 72  THR L CG2 1 
ATOM   5358 N N   . LEU D 4 79  ? -1.327  25.837  -1.221  1.00 41.92  ? 73  LEU L N   1 
ATOM   5359 C CA  . LEU D 4 79  ? -2.000  26.732  -2.152  1.00 29.91  ? 73  LEU L CA  1 
ATOM   5360 C C   . LEU D 4 79  ? -2.345  28.022  -1.422  1.00 32.85  ? 73  LEU L C   1 
ATOM   5361 O O   . LEU D 4 79  ? -2.897  27.983  -0.318  1.00 31.46  ? 73  LEU L O   1 
ATOM   5362 C CB  . LEU D 4 79  ? -3.266  26.091  -2.724  1.00 29.26  ? 73  LEU L CB  1 
ATOM   5363 C CG  . LEU D 4 79  ? -4.138  27.008  -3.585  1.00 27.67  ? 73  LEU L CG  1 
ATOM   5364 C CD1 . LEU D 4 79  ? -3.389  27.440  -4.836  1.00 28.48  ? 73  LEU L CD1 1 
ATOM   5365 C CD2 . LEU D 4 79  ? -5.448  26.327  -3.946  1.00 24.56  ? 73  LEU L CD2 1 
ATOM   5366 N N   . THR D 4 80  ? -2.014  29.159  -2.031  1.00 35.27  ? 74  THR L N   1 
ATOM   5367 C CA  . THR D 4 80  ? -2.202  30.458  -1.399  1.00 39.56  ? 74  THR L CA  1 
ATOM   5368 C C   . THR D 4 80  ? -2.995  31.369  -2.323  1.00 33.79  ? 74  THR L C   1 
ATOM   5369 O O   . THR D 4 80  ? -2.676  31.482  -3.511  1.00 32.20  ? 74  THR L O   1 
ATOM   5370 C CB  . THR D 4 80  ? -0.858  31.107  -1.054  1.00 40.12  ? 74  THR L CB  1 
ATOM   5371 O OG1 . THR D 4 80  ? 0.064   30.099  -0.624  1.00 41.65  ? 74  THR L OG1 1 
ATOM   5372 C CG2 . THR D 4 80  ? -1.032  32.126  0.063   1.00 48.19  ? 74  THR L CG2 1 
ATOM   5373 N N   . ILE D 4 81  ? -4.026  32.009  -1.777  1.00 37.72  ? 75  ILE L N   1 
ATOM   5374 C CA  . ILE D 4 81  ? -4.785  33.045  -2.471  1.00 47.91  ? 75  ILE L CA  1 
ATOM   5375 C C   . ILE D 4 81  ? -4.439  34.365  -1.808  1.00 46.41  ? 75  ILE L C   1 
ATOM   5376 O O   . ILE D 4 81  ? -4.715  34.552  -0.617  1.00 51.38  ? 75  ILE L O   1 
ATOM   5377 C CB  . ILE D 4 81  ? -6.299  32.799  -2.408  1.00 48.84  ? 75  ILE L CB  1 
ATOM   5378 C CG1 . ILE D 4 81  ? -6.595  31.300  -2.362  1.00 37.45  ? 75  ILE L CG1 1 
ATOM   5379 C CG2 . ILE D 4 81  ? -6.998  33.475  -3.600  1.00 39.07  ? 75  ILE L CG2 1 
ATOM   5380 C CD1 . ILE D 4 81  ? -6.333  30.576  -3.693  1.00 34.72  ? 75  ILE L CD1 1 
ATOM   5381 N N   . SER D 4 82  ? -3.847  35.283  -2.571  1.00 55.97  ? 76  SER L N   1 
ATOM   5382 C CA  . SER D 4 82  ? -3.381  36.535  -1.983  1.00 48.46  ? 76  SER L CA  1 
ATOM   5383 C C   . SER D 4 82  ? -4.536  37.501  -1.737  1.00 52.92  ? 76  SER L C   1 
ATOM   5384 O O   . SER D 4 82  ? -4.821  37.863  -0.591  1.00 66.52  ? 76  SER L O   1 
ATOM   5385 C CB  . SER D 4 82  ? -2.324  37.179  -2.883  1.00 49.82  ? 76  SER L CB  1 
ATOM   5386 O OG  . SER D 4 82  ? -1.176  36.356  -2.997  1.00 67.15  ? 76  SER L OG  1 
ATOM   5387 N N   . GLY D 4 83  ? -5.206  37.935  -2.802  1.00 45.27  ? 77  GLY L N   1 
ATOM   5388 C CA  . GLY D 4 83  ? -6.356  38.808  -2.655  1.00 44.80  ? 77  GLY L CA  1 
ATOM   5389 C C   . GLY D 4 83  ? -7.665  38.056  -2.764  1.00 53.71  ? 77  GLY L C   1 
ATOM   5390 O O   . GLY D 4 83  ? -8.140  37.784  -3.870  1.00 63.39  ? 77  GLY L O   1 
ATOM   5391 N N   . LEU D 4 84  ? -8.272  37.734  -1.626  1.00 42.29  ? 78  LEU L N   1 
ATOM   5392 C CA  . LEU D 4 84  ? -9.456  36.885  -1.631  1.00 44.46  ? 78  LEU L CA  1 
ATOM   5393 C C   . LEU D 4 84  ? -10.664 37.658  -2.148  1.00 49.91  ? 78  LEU L C   1 
ATOM   5394 O O   . LEU D 4 84  ? -10.955 38.765  -1.685  1.00 57.55  ? 78  LEU L O   1 
ATOM   5395 C CB  . LEU D 4 84  ? -9.717  36.345  -0.225  1.00 54.18  ? 78  LEU L CB  1 
ATOM   5396 C CG  . LEU D 4 84  ? -10.594 35.098  -0.091  1.00 39.58  ? 78  LEU L CG  1 
ATOM   5397 C CD1 . LEU D 4 84  ? -12.054 35.476  0.053   1.00 41.40  ? 78  LEU L CD1 1 
ATOM   5398 C CD2 . LEU D 4 84  ? -10.396 34.166  -1.280  1.00 29.70  ? 78  LEU L CD2 1 
ATOM   5399 N N   . GLN D 4 85  ? -11.369 37.066  -3.110  1.00 44.71  ? 79  GLN L N   1 
ATOM   5400 C CA  . GLN D 4 85  ? -12.532 37.673  -3.735  1.00 40.17  ? 79  GLN L CA  1 
ATOM   5401 C C   . GLN D 4 85  ? -13.728 36.736  -3.621  1.00 49.39  ? 79  GLN L C   1 
ATOM   5402 O O   . GLN D 4 85  ? -13.582 35.531  -3.395  1.00 55.95  ? 79  GLN L O   1 
ATOM   5403 C CB  . GLN D 4 85  ? -12.271 38.001  -5.212  1.00 37.80  ? 79  GLN L CB  1 
ATOM   5404 C CG  . GLN D 4 85  ? -11.084 38.919  -5.454  1.00 51.85  ? 79  GLN L CG  1 
ATOM   5405 C CD  . GLN D 4 85  ? -10.881 39.224  -6.926  1.00 55.42  ? 79  GLN L CD  1 
ATOM   5406 O OE1 . GLN D 4 85  ? -11.747 38.941  -7.754  1.00 49.31  ? 79  GLN L OE1 1 
ATOM   5407 N NE2 . GLN D 4 85  ? -9.732  39.801  -7.260  1.00 45.31  ? 79  GLN L NE2 1 
ATOM   5408 N N   . ALA D 4 86  ? -14.924 37.311  -3.778  1.00 47.00  ? 80  ALA L N   1 
ATOM   5409 C CA  . ALA D 4 86  ? -16.144 36.513  -3.704  1.00 47.21  ? 80  ALA L CA  1 
ATOM   5410 C C   . ALA D 4 86  ? -16.196 35.464  -4.806  1.00 48.23  ? 80  ALA L C   1 
ATOM   5411 O O   . ALA D 4 86  ? -16.873 34.440  -4.658  1.00 59.48  ? 80  ALA L O   1 
ATOM   5412 C CB  . ALA D 4 86  ? -17.374 37.419  -3.772  1.00 52.45  ? 80  ALA L CB  1 
ATOM   5413 N N   . GLU D 4 87  ? -15.497 35.702  -5.918  1.00 54.55  ? 81  GLU L N   1 
ATOM   5414 C CA  . GLU D 4 87  ? -15.435 34.732  -7.004  1.00 43.24  ? 81  GLU L CA  1 
ATOM   5415 C C   . GLU D 4 87  ? -14.697 33.458  -6.604  1.00 43.74  ? 81  GLU L C   1 
ATOM   5416 O O   . GLU D 4 87  ? -14.904 32.411  -7.228  1.00 39.26  ? 81  GLU L O   1 
ATOM   5417 C CB  . GLU D 4 87  ? -14.762 35.373  -8.221  1.00 37.87  ? 81  GLU L CB  1 
ATOM   5418 C CG  . GLU D 4 87  ? -14.708 34.502  -9.464  1.00 58.80  ? 81  GLU L CG  1 
ATOM   5419 C CD  . GLU D 4 87  ? -13.713 35.012  -10.489 1.00 70.33  ? 81  GLU L CD  1 
ATOM   5420 O OE1 . GLU D 4 87  ? -13.157 36.111  -10.280 1.00 69.69  ? 81  GLU L OE1 1 
ATOM   5421 O OE2 . GLU D 4 87  ? -13.482 34.314  -11.499 1.00 64.78  ? 81  GLU L OE2 1 
ATOM   5422 N N   . ASP D 4 88  ? -13.866 33.516  -5.567  1.00 41.61  ? 82  ASP L N   1 
ATOM   5423 C CA  . ASP D 4 88  ? -12.987 32.413  -5.203  1.00 42.80  ? 82  ASP L CA  1 
ATOM   5424 C C   . ASP D 4 88  ? -13.637 31.398  -4.270  1.00 37.30  ? 82  ASP L C   1 
ATOM   5425 O O   . ASP D 4 88  ? -12.960 30.457  -3.843  1.00 33.19  ? 82  ASP L O   1 
ATOM   5426 C CB  . ASP D 4 88  ? -11.707 32.957  -4.558  1.00 37.94  ? 82  ASP L CB  1 
ATOM   5427 C CG  . ASP D 4 88  ? -10.947 33.895  -5.474  1.00 47.50  ? 82  ASP L CG  1 
ATOM   5428 O OD1 . ASP D 4 88  ? -11.026 33.716  -6.708  1.00 43.89  ? 82  ASP L OD1 1 
ATOM   5429 O OD2 . ASP D 4 88  ? -10.271 34.812  -4.961  1.00 46.46  ? 82  ASP L OD2 1 
ATOM   5430 N N   . VAL D 4 89  ? -14.916 31.562  -3.937  1.00 34.85  ? 83  VAL L N   1 
ATOM   5431 C CA  . VAL D 4 89  ? -15.600 30.584  -3.096  1.00 32.87  ? 83  VAL L CA  1 
ATOM   5432 C C   . VAL D 4 89  ? -15.757 29.288  -3.879  1.00 30.12  ? 83  VAL L C   1 
ATOM   5433 O O   . VAL D 4 89  ? -16.424 29.252  -4.919  1.00 34.90  ? 83  VAL L O   1 
ATOM   5434 C CB  . VAL D 4 89  ? -16.959 31.113  -2.624  1.00 29.66  ? 83  VAL L CB  1 
ATOM   5435 C CG1 . VAL D 4 89  ? -17.795 29.979  -2.050  1.00 26.06  ? 83  VAL L CG1 1 
ATOM   5436 C CG2 . VAL D 4 89  ? -16.765 32.192  -1.589  1.00 33.19  ? 83  VAL L CG2 1 
ATOM   5437 N N   . ALA D 4 90  ? -15.153 28.219  -3.373  1.00 25.31  ? 84  ALA L N   1 
ATOM   5438 C CA  . ALA D 4 90  ? -15.146 26.928  -4.052  1.00 33.46  ? 84  ALA L CA  1 
ATOM   5439 C C   . ALA D 4 90  ? -14.559 25.894  -3.100  1.00 26.51  ? 84  ALA L C   1 
ATOM   5440 O O   . ALA D 4 90  ? -14.182 26.205  -1.965  1.00 26.32  ? 84  ALA L O   1 
ATOM   5441 C CB  . ALA D 4 90  ? -14.351 26.988  -5.357  1.00 27.24  ? 84  ALA L CB  1 
ATOM   5442 N N   . VAL D 4 91  ? -14.491 24.654  -3.575  1.00 21.18  ? 85  VAL L N   1 
ATOM   5443 C CA  . VAL D 4 91  ? -13.768 23.579  -2.907  1.00 27.13  ? 85  VAL L CA  1 
ATOM   5444 C C   . VAL D 4 91  ? -12.493 23.326  -3.697  1.00 21.69  ? 85  VAL L C   1 
ATOM   5445 O O   . VAL D 4 91  ? -12.537 23.179  -4.925  1.00 23.65  ? 85  VAL L O   1 
ATOM   5446 C CB  . VAL D 4 91  ? -14.616 22.300  -2.797  1.00 26.06  ? 85  VAL L CB  1 
ATOM   5447 C CG1 . VAL D 4 91  ? -13.806 21.180  -2.163  1.00 21.44  ? 85  VAL L CG1 1 
ATOM   5448 C CG2 . VAL D 4 91  ? -15.877 22.569  -1.991  1.00 23.44  ? 85  VAL L CG2 1 
ATOM   5449 N N   . TYR D 4 92  ? -11.362 23.288  -3.001  1.00 18.74  ? 86  TYR L N   1 
ATOM   5450 C CA  . TYR D 4 92  ? -10.057 23.168  -3.635  1.00 14.93  ? 86  TYR L CA  1 
ATOM   5451 C C   . TYR D 4 92  ? -9.464  21.797  -3.342  1.00 21.74  ? 86  TYR L C   1 
ATOM   5452 O O   . TYR D 4 92  ? -9.347  21.400  -2.178  1.00 22.66  ? 86  TYR L O   1 
ATOM   5453 C CB  . TYR D 4 92  ? -9.119  24.279  -3.158  1.00 19.55  ? 86  TYR L CB  1 
ATOM   5454 C CG  . TYR D 4 92  ? -9.559  25.655  -3.609  1.00 23.88  ? 86  TYR L CG  1 
ATOM   5455 C CD1 . TYR D 4 92  ? -10.458 26.401  -2.856  1.00 18.14  ? 86  TYR L CD1 1 
ATOM   5456 C CD2 . TYR D 4 92  ? -9.087  26.200  -4.796  1.00 23.96  ? 86  TYR L CD2 1 
ATOM   5457 C CE1 . TYR D 4 92  ? -10.868 27.655  -3.270  1.00 20.85  ? 86  TYR L CE1 1 
ATOM   5458 C CE2 . TYR D 4 92  ? -9.490  27.453  -5.218  1.00 24.87  ? 86  TYR L CE2 1 
ATOM   5459 C CZ  . TYR D 4 92  ? -10.380 28.176  -4.451  1.00 26.84  ? 86  TYR L CZ  1 
ATOM   5460 O OH  . TYR D 4 92  ? -10.785 29.423  -4.867  1.00 27.93  ? 86  TYR L OH  1 
ATOM   5461 N N   . TYR D 4 93  ? -9.092  21.084  -4.401  1.00 20.98  ? 87  TYR L N   1 
ATOM   5462 C CA  . TYR D 4 93  ? -8.541  19.742  -4.307  1.00 19.07  ? 87  TYR L CA  1 
ATOM   5463 C C   . TYR D 4 93  ? -7.085  19.743  -4.751  1.00 20.17  ? 87  TYR L C   1 
ATOM   5464 O O   . TYR D 4 93  ? -6.725  20.412  -5.724  1.00 25.81  ? 87  TYR L O   1 
ATOM   5465 C CB  . TYR D 4 93  ? -9.327  18.757  -5.180  1.00 21.16  ? 87  TYR L CB  1 
ATOM   5466 C CG  . TYR D 4 93  ? -10.780 18.582  -4.802  1.00 27.38  ? 87  TYR L CG  1 
ATOM   5467 C CD1 . TYR D 4 93  ? -11.169 17.596  -3.906  1.00 26.64  ? 87  TYR L CD1 1 
ATOM   5468 C CD2 . TYR D 4 93  ? -11.765 19.389  -5.357  1.00 20.23  ? 87  TYR L CD2 1 
ATOM   5469 C CE1 . TYR D 4 93  ? -12.496 17.424  -3.563  1.00 21.77  ? 87  TYR L CE1 1 
ATOM   5470 C CE2 . TYR D 4 93  ? -13.095 19.224  -5.021  1.00 26.90  ? 87  TYR L CE2 1 
ATOM   5471 C CZ  . TYR D 4 93  ? -13.454 18.241  -4.122  1.00 23.81  ? 87  TYR L CZ  1 
ATOM   5472 O OH  . TYR D 4 93  ? -14.776 18.073  -3.780  1.00 22.59  ? 87  TYR L OH  1 
ATOM   5473 N N   . CYS D 4 94  ? -6.252  18.991  -4.038  1.00 16.38  ? 88  CYS L N   1 
ATOM   5474 C CA  . CYS D 4 94  ? -4.908  18.684  -4.502  1.00 25.32  ? 88  CYS L CA  1 
ATOM   5475 C C   . CYS D 4 94  ? -4.890  17.272  -5.071  1.00 21.89  ? 88  CYS L C   1 
ATOM   5476 O O   . CYS D 4 94  ? -5.530  16.366  -4.530  1.00 28.78  ? 88  CYS L O   1 
ATOM   5477 C CB  . CYS D 4 94  ? -3.865  18.821  -3.386  1.00 24.47  ? 88  CYS L CB  1 
ATOM   5478 S SG  . CYS D 4 94  ? -4.082  17.781  -1.915  1.00 39.24  ? 88  CYS L SG  1 
ATOM   5479 N N   . GLN D 4 95  ? -4.175  17.099  -6.178  1.00 19.05  ? 89  GLN L N   1 
ATOM   5480 C CA  . GLN D 4 95  ? -4.080  15.813  -6.850  1.00 24.43  ? 89  GLN L CA  1 
ATOM   5481 C C   . GLN D 4 95  ? -2.633  15.534  -7.217  1.00 26.37  ? 89  GLN L C   1 
ATOM   5482 O O   . GLN D 4 95  ? -1.922  16.423  -7.696  1.00 29.25  ? 89  GLN L O   1 
ATOM   5483 C CB  . GLN D 4 95  ? -4.944  15.774  -8.117  1.00 17.61  ? 89  GLN L CB  1 
ATOM   5484 C CG  . GLN D 4 95  ? -4.963  14.418  -8.805  1.00 24.22  ? 89  GLN L CG  1 
ATOM   5485 C CD  . GLN D 4 95  ? -4.896  14.523  -10.316 1.00 24.23  ? 89  GLN L CD  1 
ATOM   5486 O OE1 . GLN D 4 95  ? -4.473  15.541  -10.863 1.00 28.18  ? 89  GLN L OE1 1 
ATOM   5487 N NE2 . GLN D 4 95  ? -5.316  13.466  -11.001 1.00 37.32  ? 89  GLN L NE2 1 
ATOM   5488 N N   . GLN D 4 96  ? -2.201  14.299  -6.991  1.00 22.28  ? 90  GLN L N   1 
ATOM   5489 C CA  . GLN D 4 96  ? -0.907  13.837  -7.466  1.00 21.38  ? 90  GLN L CA  1 
ATOM   5490 C C   . GLN D 4 96  ? -1.107  13.052  -8.755  1.00 19.10  ? 90  GLN L C   1 
ATOM   5491 O O   . GLN D 4 96  ? -2.070  12.292  -8.891  1.00 15.26  ? 90  GLN L O   1 
ATOM   5492 C CB  . GLN D 4 96  ? -0.197  12.978  -6.412  1.00 15.49  ? 90  GLN L CB  1 
ATOM   5493 C CG  . GLN D 4 96  ? -0.846  11.630  -6.113  1.00 17.58  ? 90  GLN L CG  1 
ATOM   5494 C CD  . GLN D 4 96  ? -0.384  10.528  -7.053  1.00 17.97  ? 90  GLN L CD  1 
ATOM   5495 O OE1 . GLN D 4 96  ? 0.648   10.652  -7.714  1.00 19.83  ? 90  GLN L OE1 1 
ATOM   5496 N NE2 . GLN D 4 96  ? -1.154  9.449   -7.122  1.00 23.31  ? 90  GLN L NE2 1 
ATOM   5497 N N   . TYR D 4 97  ? -0.207  13.264  -9.712  1.00 16.08  ? 91  TYR L N   1 
ATOM   5498 C CA  . TYR D 4 97  ? -0.254  12.547  -10.979 1.00 23.08  ? 91  TYR L CA  1 
ATOM   5499 C C   . TYR D 4 97  ? 1.117   11.988  -11.336 1.00 26.02  ? 91  TYR L C   1 
ATOM   5500 O O   . TYR D 4 97  ? 1.451   11.844  -12.516 1.00 19.06  ? 91  TYR L O   1 
ATOM   5501 C CB  . TYR D 4 97  ? -0.794  13.440  -12.098 1.00 21.84  ? 91  TYR L CB  1 
ATOM   5502 C CG  . TYR D 4 97  ? -0.104  14.780  -12.236 1.00 21.26  ? 91  TYR L CG  1 
ATOM   5503 C CD1 . TYR D 4 97  ? -0.502  15.873  -11.477 1.00 18.03  ? 91  TYR L CD1 1 
ATOM   5504 C CD2 . TYR D 4 97  ? 0.936   14.956  -13.139 1.00 23.42  ? 91  TYR L CD2 1 
ATOM   5505 C CE1 . TYR D 4 97  ? 0.125   17.099  -11.605 1.00 22.86  ? 91  TYR L CE1 1 
ATOM   5506 C CE2 . TYR D 4 97  ? 1.566   16.179  -13.276 1.00 21.30  ? 91  TYR L CE2 1 
ATOM   5507 C CZ  . TYR D 4 97  ? 1.157   17.246  -12.507 1.00 21.03  ? 91  TYR L CZ  1 
ATOM   5508 O OH  . TYR D 4 97  ? 1.785   18.463  -12.641 1.00 21.67  ? 91  TYR L OH  1 
ATOM   5509 N N   . SER D 4 98  ? 1.926   11.675  -10.320 1.00 23.21  ? 92  SER L N   1 
ATOM   5510 C CA  . SER D 4 98  ? 3.221   11.051  -10.570 1.00 24.44  ? 92  SER L CA  1 
ATOM   5511 C C   . SER D 4 98  ? 3.055   9.667   -11.181 1.00 22.28  ? 92  SER L C   1 
ATOM   5512 O O   . SER D 4 98  ? 3.779   9.300   -12.113 1.00 37.56  ? 92  SER L O   1 
ATOM   5513 C CB  . SER D 4 98  ? 4.026   10.973  -9.273  1.00 28.97  ? 92  SER L CB  1 
ATOM   5514 O OG  . SER D 4 98  ? 3.350   10.196  -8.299  1.00 44.03  ? 92  SER L OG  1 
ATOM   5515 N N   . ARG D 4 99  ? 2.108   8.884   -10.670 1.00 25.76  ? 93  ARG L N   1 
ATOM   5516 C CA  . ARG D 4 99  ? 1.843   7.559   -11.209 1.00 32.47  ? 93  ARG L CA  1 
ATOM   5517 C C   . ARG D 4 99  ? 0.386   7.201   -10.969 1.00 29.42  ? 93  ARG L C   1 
ATOM   5518 O O   . ARG D 4 99  ? -0.271  7.740   -10.075 1.00 28.18  ? 93  ARG L O   1 
ATOM   5519 C CB  . ARG D 4 99  ? 2.751   6.497   -10.580 1.00 35.82  ? 93  ARG L CB  1 
ATOM   5520 C CG  . ARG D 4 99  ? 2.530   6.297   -9.089  1.00 35.80  ? 93  ARG L CG  1 
ATOM   5521 C CD  . ARG D 4 99  ? 3.165   5.003   -8.610  1.00 57.73  ? 93  ARG L CD  1 
ATOM   5522 N NE  . ARG D 4 99  ? 3.264   4.953   -7.157  1.00 61.90  ? 93  ARG L NE  1 
ATOM   5523 C CZ  . ARG D 4 99  ? 4.256   5.489   -6.460  1.00 55.45  ? 93  ARG L CZ  1 
ATOM   5524 N NH1 . ARG D 4 99  ? 5.250   6.129   -7.054  1.00 46.94  ? 93  ARG L NH1 1 
ATOM   5525 N NH2 . ARG D 4 99  ? 4.249   5.383   -5.134  1.00 59.81  ? 93  ARG L NH2 1 
ATOM   5526 N N   . THR D 4 100 ? -0.110  6.279   -11.784 1.00 32.90  ? 94  THR L N   1 
ATOM   5527 C CA  . THR D 4 100 ? -1.441  5.738   -11.585 1.00 32.79  ? 94  THR L CA  1 
ATOM   5528 C C   . THR D 4 100 ? -1.433  4.736   -10.432 1.00 32.24  ? 94  THR L C   1 
ATOM   5529 O O   . THR D 4 100 ? -0.454  4.011   -10.237 1.00 45.62  ? 94  THR L O   1 
ATOM   5530 C CB  . THR D 4 100 ? -1.941  5.061   -12.855 1.00 37.62  ? 94  THR L CB  1 
ATOM   5531 O OG1 . THR D 4 100 ? -1.066  3.979   -13.197 1.00 47.13  ? 94  THR L OG1 1 
ATOM   5532 C CG2 . THR D 4 100 ? -1.980  6.058   -14.003 1.00 27.25  ? 94  THR L CG2 1 
ATOM   5533 N N   . PRO D 4 101 ? -2.517  4.674   -9.651  1.00 28.94  ? 95  PRO L N   1 
ATOM   5534 C CA  . PRO D 4 101 ? -3.748  5.468   -9.762  1.00 31.82  ? 95  PRO L CA  1 
ATOM   5535 C C   . PRO D 4 101 ? -3.592  6.891   -9.238  1.00 28.19  ? 95  PRO L C   1 
ATOM   5536 O O   . PRO D 4 101 ? -2.926  7.124   -8.233  1.00 27.06  ? 95  PRO L O   1 
ATOM   5537 C CB  . PRO D 4 101 ? -4.740  4.663   -8.916  1.00 30.72  ? 95  PRO L CB  1 
ATOM   5538 C CG  . PRO D 4 101 ? -3.881  4.068   -7.837  1.00 24.29  ? 95  PRO L CG  1 
ATOM   5539 C CD  . PRO D 4 101 ? -2.584  3.720   -8.527  1.00 21.23  ? 95  PRO L CD  1 
ATOM   5540 N N   . TYR D 4 102 ? -4.200  7.865   -9.908  1.00 32.32  ? 96  TYR L N   1 
ATOM   5541 C CA  . TYR D 4 102 ? -4.215  9.226   -9.394  1.00 23.22  ? 96  TYR L CA  1 
ATOM   5542 C C   . TYR D 4 102 ? -5.096  9.301   -8.153  1.00 21.24  ? 96  TYR L C   1 
ATOM   5543 O O   . TYR D 4 102 ? -6.099  8.593   -8.032  1.00 32.65  ? 96  TYR L O   1 
ATOM   5544 C CB  . TYR D 4 102 ? -4.726  10.199  -10.456 1.00 29.27  ? 96  TYR L CB  1 
ATOM   5545 C CG  . TYR D 4 102 ? -3.936  10.188  -11.746 1.00 24.37  ? 96  TYR L CG  1 
ATOM   5546 C CD1 . TYR D 4 102 ? -2.592  9.840   -11.762 1.00 19.00  ? 96  TYR L CD1 1 
ATOM   5547 C CD2 . TYR D 4 102 ? -4.540  10.527  -12.951 1.00 37.15  ? 96  TYR L CD2 1 
ATOM   5548 C CE1 . TYR D 4 102 ? -1.871  9.829   -12.943 1.00 30.26  ? 96  TYR L CE1 1 
ATOM   5549 C CE2 . TYR D 4 102 ? -3.828  10.520  -14.135 1.00 27.58  ? 96  TYR L CE2 1 
ATOM   5550 C CZ  . TYR D 4 102 ? -2.495  10.170  -14.126 1.00 31.27  ? 96  TYR L CZ  1 
ATOM   5551 O OH  . TYR D 4 102 ? -1.788  10.163  -15.305 1.00 36.79  ? 96  TYR L OH  1 
ATOM   5552 N N   . THR D 4 103 ? -4.708  10.163  -7.219  1.00 19.03  ? 97  THR L N   1 
ATOM   5553 C CA  . THR D 4 103 ? -5.432  10.312  -5.965  1.00 24.89  ? 97  THR L CA  1 
ATOM   5554 C C   . THR D 4 103 ? -5.659  11.787  -5.676  1.00 16.50  ? 97  THR L C   1 
ATOM   5555 O O   . THR D 4 103 ? -4.721  12.589  -5.739  1.00 15.05  ? 97  THR L O   1 
ATOM   5556 C CB  . THR D 4 103 ? -4.677  9.652   -4.805  1.00 27.09  ? 97  THR L CB  1 
ATOM   5557 O OG1 . THR D 4 103 ? -3.295  10.028  -4.852  1.00 30.59  ? 97  THR L OG1 1 
ATOM   5558 C CG2 . THR D 4 103 ? -4.788  8.137   -4.893  1.00 20.23  ? 97  THR L CG2 1 
ATOM   5559 N N   . PHE D 4 104 ? -6.902  12.136  -5.365  1.00 22.21  ? 98  PHE L N   1 
ATOM   5560 C CA  . PHE D 4 104 ? -7.265  13.479  -4.946  1.00 18.64  ? 98  PHE L CA  1 
ATOM   5561 C C   . PHE D 4 104 ? -7.195  13.599  -3.429  1.00 19.40  ? 98  PHE L C   1 
ATOM   5562 O O   . PHE D 4 104 ? -7.235  12.607  -2.698  1.00 25.54  ? 98  PHE L O   1 
ATOM   5563 C CB  . PHE D 4 104 ? -8.678  13.837  -5.412  1.00 19.26  ? 98  PHE L CB  1 
ATOM   5564 C CG  . PHE D 4 104 ? -8.809  14.025  -6.894  1.00 18.34  ? 98  PHE L CG  1 
ATOM   5565 C CD1 . PHE D 4 104 ? -8.561  15.258  -7.474  1.00 24.56  ? 98  PHE L CD1 1 
ATOM   5566 C CD2 . PHE D 4 104 ? -9.205  12.975  -7.707  1.00 17.11  ? 98  PHE L CD2 1 
ATOM   5567 C CE1 . PHE D 4 104 ? -8.689  15.438  -8.839  1.00 20.73  ? 98  PHE L CE1 1 
ATOM   5568 C CE2 . PHE D 4 104 ? -9.335  13.149  -9.073  1.00 20.68  ? 98  PHE L CE2 1 
ATOM   5569 C CZ  . PHE D 4 104 ? -9.077  14.381  -9.639  1.00 19.65  ? 98  PHE L CZ  1 
ATOM   5570 N N   . GLY D 4 105 ? -7.090  14.839  -2.959  1.00 18.95  ? 99  GLY L N   1 
ATOM   5571 C CA  . GLY D 4 105 ? -7.340  15.117  -1.564  1.00 17.86  ? 99  GLY L CA  1 
ATOM   5572 C C   . GLY D 4 105 ? -8.827  15.104  -1.271  1.00 19.76  ? 99  GLY L C   1 
ATOM   5573 O O   . GLY D 4 105 ? -9.664  15.044  -2.171  1.00 21.38  ? 99  GLY L O   1 
ATOM   5574 N N   . GLN D 4 106 ? -9.161  15.156  0.019   1.00 22.58  ? 100 GLN L N   1 
ATOM   5575 C CA  . GLN D 4 106 ? -10.569 15.138  0.396   1.00 20.97  ? 100 GLN L CA  1 
ATOM   5576 C C   . GLN D 4 106 ? -11.279 16.436  0.031   1.00 26.64  ? 100 GLN L C   1 
ATOM   5577 O O   . GLN D 4 106 ? -12.512 16.455  -0.035  1.00 35.51  ? 100 GLN L O   1 
ATOM   5578 C CB  . GLN D 4 106 ? -10.720 14.862  1.893   1.00 21.75  ? 100 GLN L CB  1 
ATOM   5579 C CG  . GLN D 4 106 ? -10.369 16.033  2.795   1.00 20.07  ? 100 GLN L CG  1 
ATOM   5580 C CD  . GLN D 4 106 ? -8.881  16.154  3.060   1.00 27.03  ? 100 GLN L CD  1 
ATOM   5581 O OE1 . GLN D 4 106 ? -8.061  15.531  2.384   1.00 29.35  ? 100 GLN L OE1 1 
ATOM   5582 N NE2 . GLN D 4 106 ? -8.525  16.955  4.058   1.00 23.05  ? 100 GLN L NE2 1 
ATOM   5583 N N   . GLY D 4 107 ? -10.538 17.505  -0.208  1.00 26.70  ? 101 GLY L N   1 
ATOM   5584 C CA  . GLY D 4 107 ? -11.118 18.781  -0.571  1.00 26.42  ? 101 GLY L CA  1 
ATOM   5585 C C   . GLY D 4 107 ? -11.184 19.735  0.607   1.00 27.88  ? 101 GLY L C   1 
ATOM   5586 O O   . GLY D 4 107 ? -11.376 19.337  1.761   1.00 27.04  ? 101 GLY L O   1 
ATOM   5587 N N   . THR D 4 108 ? -11.024 21.023  0.312   1.00 23.27  ? 102 THR L N   1 
ATOM   5588 C CA  . THR D 4 108 ? -11.068 22.078  1.317   1.00 29.03  ? 102 THR L CA  1 
ATOM   5589 C C   . THR D 4 108 ? -12.152 23.073  0.933   1.00 29.42  ? 102 THR L C   1 
ATOM   5590 O O   . THR D 4 108 ? -12.103 23.661  -0.152  1.00 27.60  ? 102 THR L O   1 
ATOM   5591 C CB  . THR D 4 108 ? -9.712  22.778  1.443   1.00 30.65  ? 102 THR L CB  1 
ATOM   5592 O OG1 . THR D 4 108 ? -8.741  21.858  1.959   1.00 27.04  ? 102 THR L OG1 1 
ATOM   5593 C CG2 . THR D 4 108 ? -9.812  23.979  2.374   1.00 36.58  ? 102 THR L CG2 1 
ATOM   5594 N N   . LYS D 4 109 ? -13.123 23.263  1.824   1.00 24.95  ? 103 LYS L N   1 
ATOM   5595 C CA  . LYS D 4 109 ? -14.227 24.180  1.573   1.00 26.12  ? 103 LYS L CA  1 
ATOM   5596 C C   . LYS D 4 109 ? -13.807 25.596  1.947   1.00 29.19  ? 103 LYS L C   1 
ATOM   5597 O O   . LYS D 4 109 ? -13.412 25.849  3.091   1.00 38.96  ? 103 LYS L O   1 
ATOM   5598 C CB  . LYS D 4 109 ? -15.461 23.752  2.365   1.00 33.37  ? 103 LYS L CB  1 
ATOM   5599 C CG  . LYS D 4 109 ? -16.644 24.689  2.211   1.00 55.16  ? 103 LYS L CG  1 
ATOM   5600 C CD  . LYS D 4 109 ? -17.068 24.785  0.758   1.00 51.85  ? 103 LYS L CD  1 
ATOM   5601 C CE  . LYS D 4 109 ? -17.779 26.095  0.481   1.00 46.08  ? 103 LYS L CE  1 
ATOM   5602 N NZ  . LYS D 4 109 ? -17.920 26.334  -0.981  1.00 41.21  ? 103 LYS L NZ  1 
ATOM   5603 N N   . LEU D 4 110 ? -13.889 26.517  0.989   1.00 26.79  ? 104 LEU L N   1 
ATOM   5604 C CA  . LEU D 4 110 ? -13.496 27.905  1.193   1.00 36.91  ? 104 LEU L CA  1 
ATOM   5605 C C   . LEU D 4 110 ? -14.713 28.809  1.056   1.00 31.04  ? 104 LEU L C   1 
ATOM   5606 O O   . LEU D 4 110 ? -15.427 28.749  0.050   1.00 32.72  ? 104 LEU L O   1 
ATOM   5607 C CB  . LEU D 4 110 ? -12.407 28.323  0.199   1.00 32.54  ? 104 LEU L CB  1 
ATOM   5608 C CG  . LEU D 4 110 ? -11.886 29.754  0.348   1.00 34.94  ? 104 LEU L CG  1 
ATOM   5609 C CD1 . LEU D 4 110 ? -11.448 30.017  1.780   1.00 28.64  ? 104 LEU L CD1 1 
ATOM   5610 C CD2 . LEU D 4 110 ? -10.742 30.018  -0.619  1.00 35.36  ? 104 LEU L CD2 1 
ATOM   5611 N N   . GLU D 4 111 ? -14.939 29.649  2.066   1.00 32.83  ? 105 GLU L N   1 
ATOM   5612 C CA  . GLU D 4 111 ? -16.068 30.567  2.098   1.00 32.32  ? 105 GLU L CA  1 
ATOM   5613 C C   . GLU D 4 111 ? -15.592 31.949  2.526   1.00 35.03  ? 105 GLU L C   1 
ATOM   5614 O O   . GLU D 4 111 ? -14.527 32.103  3.129   1.00 35.94  ? 105 GLU L O   1 
ATOM   5615 C CB  . GLU D 4 111 ? -17.164 30.081  3.056   1.00 32.97  ? 105 GLU L CB  1 
ATOM   5616 C CG  . GLU D 4 111 ? -16.741 30.085  4.517   1.00 38.35  ? 105 GLU L CG  1 
ATOM   5617 C CD  . GLU D 4 111 ? -17.885 29.772  5.461   1.00 39.68  ? 105 GLU L CD  1 
ATOM   5618 O OE1 . GLU D 4 111 ? -19.045 29.736  5.001   1.00 42.03  ? 105 GLU L OE1 1 
ATOM   5619 O OE2 . GLU D 4 111 ? -17.625 29.563  6.664   1.00 53.94  ? 105 GLU L OE2 1 
ATOM   5620 N N   . ILE D 4 112 ? -16.400 32.960  2.204   1.00 32.44  ? 106 ILE L N   1 
ATOM   5621 C CA  . ILE D 4 112 ? -16.106 34.321  2.636   1.00 33.63  ? 106 ILE L CA  1 
ATOM   5622 C C   . ILE D 4 112 ? -16.329 34.431  4.137   1.00 28.44  ? 106 ILE L C   1 
ATOM   5623 O O   . ILE D 4 112 ? -17.367 34.005  4.660   1.00 24.58  ? 106 ILE L O   1 
ATOM   5624 C CB  . ILE D 4 112 ? -16.979 35.335  1.881   1.00 34.84  ? 106 ILE L CB  1 
ATOM   5625 C CG1 . ILE D 4 112 ? -16.925 35.089  0.374   1.00 29.10  ? 106 ILE L CG1 1 
ATOM   5626 C CG2 . ILE D 4 112 ? -16.534 36.755  2.199   1.00 33.37  ? 106 ILE L CG2 1 
ATOM   5627 C CD1 . ILE D 4 112 ? -15.580 35.360  -0.243  1.00 30.77  ? 106 ILE L CD1 1 
ATOM   5628 N N   . LYS D 4 113 ? -15.356 35.004  4.841   1.00 36.63  ? 107 LYS L N   1 
ATOM   5629 C CA  . LYS D 4 113 ? -15.492 35.268  6.271   1.00 36.47  ? 107 LYS L CA  1 
ATOM   5630 C C   . LYS D 4 113 ? -15.987 36.699  6.437   1.00 45.17  ? 107 LYS L C   1 
ATOM   5631 O O   . LYS D 4 113 ? -15.200 37.648  6.411   1.00 49.52  ? 107 LYS L O   1 
ATOM   5632 C CB  . LYS D 4 113 ? -14.173 35.048  7.001   1.00 35.58  ? 107 LYS L CB  1 
ATOM   5633 C CG  . LYS D 4 113 ? -14.315 34.979  8.514   1.00 44.94  ? 107 LYS L CG  1 
ATOM   5634 C CD  . LYS D 4 113 ? -13.026 35.376  9.213   1.00 52.07  ? 107 LYS L CD  1 
ATOM   5635 C CE  . LYS D 4 113 ? -13.059 35.012  10.688  1.00 53.29  ? 107 LYS L CE  1 
ATOM   5636 N NZ  . LYS D 4 113 ? -12.993 33.537  10.887  1.00 67.29  ? 107 LYS L NZ  1 
ATOM   5637 N N   . ARG D 4 114 ? -17.296 36.857  6.599   1.00 41.22  ? 108 ARG L N   1 
ATOM   5638 C CA  . ARG D 4 114 ? -17.889 38.157  6.855   1.00 27.47  ? 108 ARG L CA  1 
ATOM   5639 C C   . ARG D 4 114 ? -18.168 38.311  8.347   1.00 31.56  ? 108 ARG L C   1 
ATOM   5640 O O   . ARG D 4 114 ? -17.927 37.409  9.153   1.00 29.57  ? 108 ARG L O   1 
ATOM   5641 C CB  . ARG D 4 114 ? -19.169 38.342  6.038   1.00 26.30  ? 108 ARG L CB  1 
ATOM   5642 C CG  . ARG D 4 114 ? -20.281 37.372  6.400   1.00 33.16  ? 108 ARG L CG  1 
ATOM   5643 C CD  . ARG D 4 114 ? -21.646 37.970  6.106   1.00 40.03  ? 108 ARG L CD  1 
ATOM   5644 N NE  . ARG D 4 114 ? -21.983 39.038  7.040   1.00 36.12  ? 108 ARG L NE  1 
ATOM   5645 C CZ  . ARG D 4 114 ? -22.992 39.885  6.883   1.00 42.50  ? 108 ARG L CZ  1 
ATOM   5646 N NH1 . ARG D 4 114 ? -23.776 39.837  5.818   1.00 36.56  ? 108 ARG L NH1 1 
ATOM   5647 N NH2 . ARG D 4 114 ? -23.215 40.807  7.814   1.00 47.16  ? 108 ARG L NH2 1 
ATOM   5648 N N   . THR D 4 115 ? -18.683 39.478  8.716   1.00 42.78  ? 109 THR L N   1 
ATOM   5649 C CA  . THR D 4 115 ? -19.043 39.725  10.101  1.00 42.63  ? 109 THR L CA  1 
ATOM   5650 C C   . THR D 4 115 ? -20.301 38.942  10.469  1.00 36.11  ? 109 THR L C   1 
ATOM   5651 O O   . THR D 4 115 ? -21.116 38.581  9.615   1.00 38.46  ? 109 THR L O   1 
ATOM   5652 C CB  . THR D 4 115 ? -19.253 41.219  10.342  1.00 48.04  ? 109 THR L CB  1 
ATOM   5653 O OG1 . THR D 4 115 ? -20.326 41.691  9.518   1.00 51.79  ? 109 THR L OG1 1 
ATOM   5654 C CG2 . THR D 4 115 ? -17.985 41.985  9.994   1.00 38.53  ? 109 THR L CG2 1 
ATOM   5655 N N   . VAL D 4 116 ? -20.446 38.675  11.769  1.00 25.24  ? 110 VAL L N   1 
ATOM   5656 C CA  . VAL D 4 116 ? -21.543 37.842  12.245  1.00 26.07  ? 110 VAL L CA  1 
ATOM   5657 C C   . VAL D 4 116 ? -22.875 38.518  11.955  1.00 29.41  ? 110 VAL L C   1 
ATOM   5658 O O   . VAL D 4 116 ? -23.078 39.696  12.276  1.00 38.65  ? 110 VAL L O   1 
ATOM   5659 C CB  . VAL D 4 116 ? -21.379 37.551  13.744  1.00 31.78  ? 110 VAL L CB  1 
ATOM   5660 C CG1 . VAL D 4 116 ? -22.580 36.785  14.269  1.00 31.51  ? 110 VAL L CG1 1 
ATOM   5661 C CG2 . VAL D 4 116 ? -20.097 36.774  13.995  1.00 40.28  ? 110 VAL L CG2 1 
ATOM   5662 N N   . ALA D 4 117 ? -23.790 37.770  11.341  1.00 31.97  ? 111 ALA L N   1 
ATOM   5663 C CA  . ALA D 4 117 ? -25.133 38.248  11.045  1.00 24.14  ? 111 ALA L CA  1 
ATOM   5664 C C   . ALA D 4 117 ? -26.143 37.277  11.634  1.00 34.69  ? 111 ALA L C   1 
ATOM   5665 O O   . ALA D 4 117 ? -26.075 36.072  11.373  1.00 33.63  ? 111 ALA L O   1 
ATOM   5666 C CB  . ALA D 4 117 ? -25.352 38.395  9.536   1.00 19.30  ? 111 ALA L CB  1 
ATOM   5667 N N   . ALA D 4 118 ? -27.071 37.799  12.430  1.00 43.62  ? 112 ALA L N   1 
ATOM   5668 C CA  . ALA D 4 118 ? -28.084 36.956  13.038  1.00 29.69  ? 112 ALA L CA  1 
ATOM   5669 C C   . ALA D 4 118 ? -29.141 36.560  12.007  1.00 35.95  ? 112 ALA L C   1 
ATOM   5670 O O   . ALA D 4 118 ? -29.438 37.322  11.084  1.00 36.61  ? 112 ALA L O   1 
ATOM   5671 C CB  . ALA D 4 118 ? -28.744 37.673  14.212  1.00 32.43  ? 112 ALA L CB  1 
ATOM   5672 N N   . PRO D 4 119 ? -29.718 35.369  12.139  1.00 39.49  ? 113 PRO L N   1 
ATOM   5673 C CA  . PRO D 4 119 ? -30.779 34.957  11.218  1.00 31.19  ? 113 PRO L CA  1 
ATOM   5674 C C   . PRO D 4 119 ? -32.127 35.549  11.591  1.00 35.92  ? 113 PRO L C   1 
ATOM   5675 O O   . PRO D 4 119 ? -32.404 35.859  12.752  1.00 37.23  ? 113 PRO L O   1 
ATOM   5676 C CB  . PRO D 4 119 ? -30.797 33.432  11.368  1.00 35.82  ? 113 PRO L CB  1 
ATOM   5677 C CG  . PRO D 4 119 ? -30.345 33.205  12.769  1.00 30.22  ? 113 PRO L CG  1 
ATOM   5678 C CD  . PRO D 4 119 ? -29.334 34.285  13.062  1.00 32.69  ? 113 PRO L CD  1 
ATOM   5679 N N   . SER D 4 120 ? -32.970 35.702  10.575  1.00 27.77  ? 114 SER L N   1 
ATOM   5680 C CA  . SER D 4 120 ? -34.378 36.018  10.761  1.00 28.59  ? 114 SER L CA  1 
ATOM   5681 C C   . SER D 4 120 ? -35.169 34.719  10.694  1.00 28.63  ? 114 SER L C   1 
ATOM   5682 O O   . SER D 4 120 ? -35.046 33.964  9.724   1.00 32.88  ? 114 SER L O   1 
ATOM   5683 C CB  . SER D 4 120 ? -34.869 37.004  9.700   1.00 31.95  ? 114 SER L CB  1 
ATOM   5684 O OG  . SER D 4 120 ? -34.156 38.227  9.773   1.00 36.17  ? 114 SER L OG  1 
ATOM   5685 N N   . VAL D 4 121 ? -35.972 34.459  11.721  1.00 24.13  ? 115 VAL L N   1 
ATOM   5686 C CA  . VAL D 4 121 ? -36.626 33.168  11.903  1.00 26.84  ? 115 VAL L CA  1 
ATOM   5687 C C   . VAL D 4 121 ? -38.104 33.309  11.570  1.00 26.00  ? 115 VAL L C   1 
ATOM   5688 O O   . VAL D 4 121 ? -38.776 34.225  12.058  1.00 40.20  ? 115 VAL L O   1 
ATOM   5689 C CB  . VAL D 4 121 ? -36.432 32.634  13.333  1.00 30.89  ? 115 VAL L CB  1 
ATOM   5690 C CG1 . VAL D 4 121 ? -36.998 31.228  13.452  1.00 22.40  ? 115 VAL L CG1 1 
ATOM   5691 C CG2 . VAL D 4 121 ? -34.959 32.655  13.708  1.00 21.36  ? 115 VAL L CG2 1 
ATOM   5692 N N   . PHE D 4 122 ? -38.604 32.401  10.734  1.00 32.32  ? 116 PHE L N   1 
ATOM   5693 C CA  . PHE D 4 122 ? -40.015 32.322  10.389  1.00 28.70  ? 116 PHE L CA  1 
ATOM   5694 C C   . PHE D 4 122 ? -40.473 30.877  10.512  1.00 25.10  ? 116 PHE L C   1 
ATOM   5695 O O   . PHE D 4 122 ? -39.692 29.944  10.309  1.00 31.92  ? 116 PHE L O   1 
ATOM   5696 C CB  . PHE D 4 122 ? -40.284 32.830  8.965   1.00 32.97  ? 116 PHE L CB  1 
ATOM   5697 C CG  . PHE D 4 122 ? -39.787 34.223  8.712   1.00 35.32  ? 116 PHE L CG  1 
ATOM   5698 C CD1 . PHE D 4 122 ? -40.572 35.321  9.025   1.00 34.74  ? 116 PHE L CD1 1 
ATOM   5699 C CD2 . PHE D 4 122 ? -38.537 34.436  8.153   1.00 30.27  ? 116 PHE L CD2 1 
ATOM   5700 C CE1 . PHE D 4 122 ? -40.118 36.606  8.791   1.00 33.88  ? 116 PHE L CE1 1 
ATOM   5701 C CE2 . PHE D 4 122 ? -38.077 35.717  7.916   1.00 37.09  ? 116 PHE L CE2 1 
ATOM   5702 C CZ  . PHE D 4 122 ? -38.869 36.804  8.235   1.00 37.60  ? 116 PHE L CZ  1 
ATOM   5703 N N   . ILE D 4 123 ? -41.748 30.696  10.848  1.00 29.24  ? 117 ILE L N   1 
ATOM   5704 C CA  . ILE D 4 123 ? -42.343 29.373  10.985  1.00 29.85  ? 117 ILE L CA  1 
ATOM   5705 C C   . ILE D 4 123 ? -43.624 29.329  10.163  1.00 29.94  ? 117 ILE L C   1 
ATOM   5706 O O   . ILE D 4 123 ? -44.409 30.285  10.163  1.00 36.02  ? 117 ILE L O   1 
ATOM   5707 C CB  . ILE D 4 123 ? -42.610 29.014  12.464  1.00 28.91  ? 117 ILE L CB  1 
ATOM   5708 C CG1 . ILE D 4 123 ? -43.157 27.590  12.586  1.00 28.78  ? 117 ILE L CG1 1 
ATOM   5709 C CG2 . ILE D 4 123 ? -43.550 30.023  13.118  1.00 37.75  ? 117 ILE L CG2 1 
ATOM   5710 C CD1 . ILE D 4 123 ? -43.220 27.083  14.009  1.00 28.29  ? 117 ILE L CD1 1 
ATOM   5711 N N   . PHE D 4 124 ? -43.820 28.232  9.440   1.00 28.27  ? 118 PHE L N   1 
ATOM   5712 C CA  . PHE D 4 124 ? -44.974 28.073  8.555   1.00 30.80  ? 118 PHE L CA  1 
ATOM   5713 C C   . PHE D 4 124 ? -45.784 26.848  8.952   1.00 28.72  ? 118 PHE L C   1 
ATOM   5714 O O   . PHE D 4 124 ? -45.277 25.714  8.849   1.00 27.22  ? 118 PHE L O   1 
ATOM   5715 C CB  . PHE D 4 124 ? -44.524 27.959  7.099   1.00 32.17  ? 118 PHE L CB  1 
ATOM   5716 C CG  . PHE D 4 124 ? -43.751 29.149  6.607   1.00 30.16  ? 118 PHE L CG  1 
ATOM   5717 C CD1 . PHE D 4 124 ? -44.408 30.254  6.095   1.00 33.51  ? 118 PHE L CD1 1 
ATOM   5718 C CD2 . PHE D 4 124 ? -42.367 29.160  6.655   1.00 27.18  ? 118 PHE L CD2 1 
ATOM   5719 C CE1 . PHE D 4 124 ? -43.699 31.350  5.641   1.00 32.00  ? 118 PHE L CE1 1 
ATOM   5720 C CE2 . PHE D 4 124 ? -41.652 30.253  6.203   1.00 30.95  ? 118 PHE L CE2 1 
ATOM   5721 C CZ  . PHE D 4 124 ? -42.319 31.349  5.695   1.00 29.85  ? 118 PHE L CZ  1 
ATOM   5722 N N   . PRO D 4 125 ? -47.022 27.011  9.408   1.00 35.33  ? 119 PRO L N   1 
ATOM   5723 C CA  . PRO D 4 125 ? -47.872 25.851  9.700   1.00 28.98  ? 119 PRO L CA  1 
ATOM   5724 C C   . PRO D 4 125 ? -48.231 25.111  8.425   1.00 29.47  ? 119 PRO L C   1 
ATOM   5725 O O   . PRO D 4 125 ? -48.144 25.677  7.325   1.00 37.03  ? 119 PRO L O   1 
ATOM   5726 C CB  . PRO D 4 125 ? -49.117 26.478  10.349  1.00 30.90  ? 119 PRO L CB  1 
ATOM   5727 C CG  . PRO D 4 125 ? -48.678 27.834  10.806  1.00 36.30  ? 119 PRO L CG  1 
ATOM   5728 C CD  . PRO D 4 125 ? -47.659 28.277  9.804   1.00 30.29  ? 119 PRO L CD  1 
ATOM   5729 N N   . PRO D 4 126 ? -48.618 23.839  8.523   1.00 38.94  ? 120 PRO L N   1 
ATOM   5730 C CA  . PRO D 4 126 ? -49.026 23.104  7.320   1.00 34.07  ? 120 PRO L CA  1 
ATOM   5731 C C   . PRO D 4 126 ? -50.275 23.708  6.697   1.00 39.80  ? 120 PRO L C   1 
ATOM   5732 O O   . PRO D 4 126 ? -51.167 24.199  7.393   1.00 45.62  ? 120 PRO L O   1 
ATOM   5733 C CB  . PRO D 4 126 ? -49.284 21.686  7.841   1.00 31.37  ? 120 PRO L CB  1 
ATOM   5734 C CG  . PRO D 4 126 ? -49.582 21.866  9.290   1.00 29.94  ? 120 PRO L CG  1 
ATOM   5735 C CD  . PRO D 4 126 ? -48.721 23.010  9.737   1.00 31.72  ? 120 PRO L CD  1 
ATOM   5736 N N   . SER D 4 127 ? -50.329 23.670  5.369   1.00 48.09  ? 121 SER L N   1 
ATOM   5737 C CA  . SER D 4 127 ? -51.496 24.159  4.651   1.00 41.34  ? 121 SER L CA  1 
ATOM   5738 C C   . SER D 4 127 ? -52.674 23.208  4.833   1.00 44.79  ? 121 SER L C   1 
ATOM   5739 O O   . SER D 4 127 ? -52.504 21.998  5.005   1.00 48.48  ? 121 SER L O   1 
ATOM   5740 C CB  . SER D 4 127 ? -51.181 24.320  3.164   1.00 35.85  ? 121 SER L CB  1 
ATOM   5741 O OG  . SER D 4 127 ? -50.837 23.075  2.580   1.00 41.08  ? 121 SER L OG  1 
ATOM   5742 N N   . ASP D 4 128 ? -53.884 23.773  4.799   1.00 48.64  ? 122 ASP L N   1 
ATOM   5743 C CA  . ASP D 4 128 ? -55.083 22.949  4.915   1.00 50.76  ? 122 ASP L CA  1 
ATOM   5744 C C   . ASP D 4 128 ? -55.217 21.984  3.744   1.00 48.16  ? 122 ASP L C   1 
ATOM   5745 O O   . ASP D 4 128 ? -55.798 20.904  3.896   1.00 49.81  ? 122 ASP L O   1 
ATOM   5746 C CB  . ASP D 4 128 ? -56.326 23.834  5.023   1.00 54.86  ? 122 ASP L CB  1 
ATOM   5747 C CG  . ASP D 4 128 ? -56.547 24.359  6.429   1.00 68.65  ? 122 ASP L CG  1 
ATOM   5748 O OD1 . ASP D 4 128 ? -55.823 23.924  7.350   1.00 72.21  ? 122 ASP L OD1 1 
ATOM   5749 O OD2 . ASP D 4 128 ? -57.445 25.207  6.616   1.00 74.95  ? 122 ASP L OD2 1 
ATOM   5750 N N   . GLU D 4 129 ? -54.694 22.353  2.572   1.00 41.32  ? 123 GLU L N   1 
ATOM   5751 C CA  . GLU D 4 129 ? -54.707 21.432  1.440   1.00 38.28  ? 123 GLU L CA  1 
ATOM   5752 C C   . GLU D 4 129 ? -53.871 20.192  1.729   1.00 50.68  ? 123 GLU L C   1 
ATOM   5753 O O   . GLU D 4 129 ? -54.284 19.068  1.418   1.00 45.93  ? 123 GLU L O   1 
ATOM   5754 C CB  . GLU D 4 129 ? -54.199 22.134  0.181   1.00 36.92  ? 123 GLU L CB  1 
ATOM   5755 C CG  . GLU D 4 129 ? -54.157 21.231  -1.040  1.00 46.61  ? 123 GLU L CG  1 
ATOM   5756 C CD  . GLU D 4 129 ? -53.133 21.676  -2.064  1.00 68.52  ? 123 GLU L CD  1 
ATOM   5757 O OE1 . GLU D 4 129 ? -52.701 22.847  -2.005  1.00 66.01  ? 123 GLU L OE1 1 
ATOM   5758 O OE2 . GLU D 4 129 ? -52.753 20.853  -2.925  1.00 58.80  ? 123 GLU L OE2 1 
ATOM   5759 N N   . GLN D 4 130 ? -52.688 20.375  2.323   1.00 50.76  ? 124 GLN L N   1 
ATOM   5760 C CA  . GLN D 4 130 ? -51.837 19.232  2.640   1.00 45.59  ? 124 GLN L CA  1 
ATOM   5761 C C   . GLN D 4 130 ? -52.441 18.383  3.752   1.00 40.76  ? 124 GLN L C   1 
ATOM   5762 O O   . GLN D 4 130 ? -52.317 17.153  3.737   1.00 49.65  ? 124 GLN L O   1 
ATOM   5763 C CB  . GLN D 4 130 ? -50.438 19.704  3.031   1.00 42.44  ? 124 GLN L CB  1 
ATOM   5764 C CG  . GLN D 4 130 ? -49.460 18.565  3.270   1.00 34.15  ? 124 GLN L CG  1 
ATOM   5765 C CD  . GLN D 4 130 ? -48.146 19.032  3.858   1.00 37.23  ? 124 GLN L CD  1 
ATOM   5766 O OE1 . GLN D 4 130 ? -48.016 20.177  4.289   1.00 39.74  ? 124 GLN L OE1 1 
ATOM   5767 N NE2 . GLN D 4 130 ? -47.160 18.142  3.878   1.00 35.34  ? 124 GLN L NE2 1 
ATOM   5768 N N   . LEU D 4 131 ? -53.090 19.024  4.728   1.00 45.02  ? 125 LEU L N   1 
ATOM   5769 C CA  . LEU D 4 131 ? -53.723 18.280  5.813   1.00 47.45  ? 125 LEU L CA  1 
ATOM   5770 C C   . LEU D 4 131 ? -54.787 17.329  5.283   1.00 53.79  ? 125 LEU L C   1 
ATOM   5771 O O   . LEU D 4 131 ? -54.962 16.223  5.808   1.00 60.07  ? 125 LEU L O   1 
ATOM   5772 C CB  . LEU D 4 131 ? -54.327 19.248  6.830   1.00 37.32  ? 125 LEU L CB  1 
ATOM   5773 C CG  . LEU D 4 131 ? -53.323 19.981  7.718   1.00 41.12  ? 125 LEU L CG  1 
ATOM   5774 C CD1 . LEU D 4 131 ? -54.003 21.088  8.507   1.00 51.53  ? 125 LEU L CD1 1 
ATOM   5775 C CD2 . LEU D 4 131 ? -52.644 18.995  8.653   1.00 44.20  ? 125 LEU L CD2 1 
ATOM   5776 N N   . LYS D 4 132 ? -55.507 17.742  4.239   1.00 51.80  ? 126 LYS L N   1 
ATOM   5777 C CA  . LYS D 4 132 ? -56.500 16.873  3.621   1.00 52.31  ? 126 LYS L CA  1 
ATOM   5778 C C   . LYS D 4 132 ? -55.872 15.625  3.014   1.00 57.62  ? 126 LYS L C   1 
ATOM   5779 O O   . LYS D 4 132 ? -56.558 14.608  2.867   1.00 58.68  ? 126 LYS L O   1 
ATOM   5780 C CB  . LYS D 4 132 ? -57.271 17.652  2.554   1.00 54.37  ? 126 LYS L CB  1 
ATOM   5781 C CG  . LYS D 4 132 ? -58.706 17.198  2.348   1.00 59.75  ? 126 LYS L CG  1 
ATOM   5782 C CD  . LYS D 4 132 ? -59.418 18.100  1.352   1.00 69.03  ? 126 LYS L CD  1 
ATOM   5783 C CE  . LYS D 4 132 ? -60.861 17.672  1.140   1.00 70.20  ? 126 LYS L CE  1 
ATOM   5784 N NZ  . LYS D 4 132 ? -61.534 18.497  0.100   1.00 66.16  ? 126 LYS L NZ  1 
ATOM   5785 N N   . SER D 4 133 ? -54.586 15.676  2.663   1.00 52.01  ? 127 SER L N   1 
ATOM   5786 C CA  . SER D 4 133 ? -53.907 14.529  2.074   1.00 45.75  ? 127 SER L CA  1 
ATOM   5787 C C   . SER D 4 133 ? -53.385 13.542  3.112   1.00 56.89  ? 127 SER L C   1 
ATOM   5788 O O   . SER D 4 133 ? -52.860 12.491  2.729   1.00 62.34  ? 127 SER L O   1 
ATOM   5789 C CB  . SER D 4 133 ? -52.747 14.999  1.194   1.00 56.53  ? 127 SER L CB  1 
ATOM   5790 O OG  . SER D 4 133 ? -51.760 15.657  1.969   1.00 57.37  ? 127 SER L OG  1 
ATOM   5791 N N   . GLY D 4 134 ? -53.502 13.852  4.400   1.00 47.85  ? 128 GLY L N   1 
ATOM   5792 C CA  . GLY D 4 134 ? -53.084 12.939  5.443   1.00 46.34  ? 128 GLY L CA  1 
ATOM   5793 C C   . GLY D 4 134 ? -51.684 13.143  5.978   1.00 53.99  ? 128 GLY L C   1 
ATOM   5794 O O   . GLY D 4 134 ? -51.229 12.332  6.794   1.00 47.92  ? 128 GLY L O   1 
ATOM   5795 N N   . THR D 4 135 ? -50.986 14.193  5.550   1.00 56.79  ? 129 THR L N   1 
ATOM   5796 C CA  . THR D 4 135 ? -49.638 14.480  6.018   1.00 44.26  ? 129 THR L CA  1 
ATOM   5797 C C   . THR D 4 135 ? -49.545 15.946  6.417   1.00 36.83  ? 129 THR L C   1 
ATOM   5798 O O   . THR D 4 135 ? -50.214 16.806  5.839   1.00 45.61  ? 129 THR L O   1 
ATOM   5799 C CB  . THR D 4 135 ? -48.587 14.159  4.942   1.00 46.94  ? 129 THR L CB  1 
ATOM   5800 O OG1 . THR D 4 135 ? -48.895 12.899  4.332   1.00 51.68  ? 129 THR L OG1 1 
ATOM   5801 C CG2 . THR D 4 135 ? -47.194 14.083  5.554   1.00 44.35  ? 129 THR L CG2 1 
ATOM   5802 N N   . ALA D 4 136 ? -48.715 16.223  7.420   1.00 33.68  ? 130 ALA L N   1 
ATOM   5803 C CA  . ALA D 4 136 ? -48.498 17.579  7.903   1.00 42.19  ? 130 ALA L CA  1 
ATOM   5804 C C   . ALA D 4 136 ? -47.010 17.890  7.880   1.00 35.43  ? 130 ALA L C   1 
ATOM   5805 O O   . ALA D 4 136 ? -46.199 17.096  8.367   1.00 43.37  ? 130 ALA L O   1 
ATOM   5806 C CB  . ALA D 4 136 ? -49.055 17.762  9.318   1.00 37.68  ? 130 ALA L CB  1 
ATOM   5807 N N   . SER D 4 137 ? -46.656 19.041  7.312   1.00 30.48  ? 131 SER L N   1 
ATOM   5808 C CA  . SER D 4 137 ? -45.276 19.503  7.263   1.00 25.82  ? 131 SER L CA  1 
ATOM   5809 C C   . SER D 4 137 ? -45.204 20.913  7.827   1.00 29.14  ? 131 SER L C   1 
ATOM   5810 O O   . SER D 4 137 ? -45.994 21.781  7.441   1.00 31.01  ? 131 SER L O   1 
ATOM   5811 C CB  . SER D 4 137 ? -44.727 19.474  5.832   1.00 29.94  ? 131 SER L CB  1 
ATOM   5812 O OG  . SER D 4 137 ? -44.609 18.144  5.356   1.00 31.97  ? 131 SER L OG  1 
ATOM   5813 N N   . VAL D 4 138 ? -44.260 21.137  8.738   1.00 25.20  ? 132 VAL L N   1 
ATOM   5814 C CA  . VAL D 4 138 ? -44.017 22.445  9.333   1.00 22.18  ? 132 VAL L CA  1 
ATOM   5815 C C   . VAL D 4 138 ? -42.612 22.881  8.944   1.00 21.22  ? 132 VAL L C   1 
ATOM   5816 O O   . VAL D 4 138 ? -41.652 22.121  9.118   1.00 26.09  ? 132 VAL L O   1 
ATOM   5817 C CB  . VAL D 4 138 ? -44.180 22.415  10.864  1.00 22.51  ? 132 VAL L CB  1 
ATOM   5818 C CG1 . VAL D 4 138 ? -44.151 23.826  11.427  1.00 19.59  ? 132 VAL L CG1 1 
ATOM   5819 C CG2 . VAL D 4 138 ? -45.471 21.706  11.248  1.00 24.93  ? 132 VAL L CG2 1 
ATOM   5820 N N   . VAL D 4 139 ? -42.492 24.096  8.417   1.00 17.60  ? 133 VAL L N   1 
ATOM   5821 C CA  . VAL D 4 139 ? -41.237 24.606  7.878   1.00 23.55  ? 133 VAL L CA  1 
ATOM   5822 C C   . VAL D 4 139 ? -40.780 25.783  8.728   1.00 30.60  ? 133 VAL L C   1 
ATOM   5823 O O   . VAL D 4 139 ? -41.555 26.712  8.981   1.00 35.33  ? 133 VAL L O   1 
ATOM   5824 C CB  . VAL D 4 139 ? -41.382 25.025  6.404   1.00 25.50  ? 133 VAL L CB  1 
ATOM   5825 C CG1 . VAL D 4 139 ? -40.078 25.615  5.888   1.00 22.40  ? 133 VAL L CG1 1 
ATOM   5826 C CG2 . VAL D 4 139 ? -41.807 23.837  5.556   1.00 16.69  ? 133 VAL L CG2 1 
ATOM   5827 N N   . CYS D 4 140 ? -39.524 25.738  9.165   1.00 19.13  ? 134 CYS L N   1 
ATOM   5828 C CA  . CYS D 4 140 ? -38.892 26.831  9.890   1.00 19.68  ? 134 CYS L CA  1 
ATOM   5829 C C   . CYS D 4 140 ? -37.785 27.417  9.024   1.00 28.37  ? 134 CYS L C   1 
ATOM   5830 O O   . CYS D 4 140 ? -36.909 26.685  8.551   1.00 22.48  ? 134 CYS L O   1 
ATOM   5831 C CB  . CYS D 4 140 ? -38.329 26.350  11.228  1.00 20.63  ? 134 CYS L CB  1 
ATOM   5832 S SG  . CYS D 4 140 ? -37.803 27.669  12.338  1.00 53.19  ? 134 CYS L SG  1 
ATOM   5833 N N   . LEU D 4 141 ? -37.824 28.730  8.822   1.00 30.82  ? 135 LEU L N   1 
ATOM   5834 C CA  . LEU D 4 141 ? -36.923 29.412  7.904   1.00 22.35  ? 135 LEU L CA  1 
ATOM   5835 C C   . LEU D 4 141 ? -35.937 30.277  8.677   1.00 24.75  ? 135 LEU L C   1 
ATOM   5836 O O   . LEU D 4 141 ? -36.341 31.115  9.488   1.00 27.13  ? 135 LEU L O   1 
ATOM   5837 C CB  . LEU D 4 141 ? -37.709 30.272  6.912   1.00 29.11  ? 135 LEU L CB  1 
ATOM   5838 C CG  . LEU D 4 141 ? -36.887 31.154  5.971   1.00 35.02  ? 135 LEU L CG  1 
ATOM   5839 C CD1 . LEU D 4 141 ? -35.953 30.311  5.117   1.00 32.10  ? 135 LEU L CD1 1 
ATOM   5840 C CD2 . LEU D 4 141 ? -37.802 31.997  5.097   1.00 25.39  ? 135 LEU L CD2 1 
ATOM   5841 N N   . LEU D 4 142 ? -34.649 30.064  8.423   1.00 27.85  ? 136 LEU L N   1 
ATOM   5842 C CA  . LEU D 4 142 ? -33.579 30.927  8.908   1.00 24.62  ? 136 LEU L CA  1 
ATOM   5843 C C   . LEU D 4 142 ? -32.988 31.643  7.701   1.00 26.54  ? 136 LEU L C   1 
ATOM   5844 O O   . LEU D 4 142 ? -32.482 30.991  6.782   1.00 30.78  ? 136 LEU L O   1 
ATOM   5845 C CB  . LEU D 4 142 ? -32.501 30.126  9.640   1.00 28.97  ? 136 LEU L CB  1 
ATOM   5846 C CG  . LEU D 4 142 ? -32.761 29.576  11.046  1.00 31.29  ? 136 LEU L CG  1 
ATOM   5847 C CD1 . LEU D 4 142 ? -33.837 28.498  11.059  1.00 17.37  ? 136 LEU L CD1 1 
ATOM   5848 C CD2 . LEU D 4 142 ? -31.462 29.038  11.625  1.00 19.79  ? 136 LEU L CD2 1 
ATOM   5849 N N   . ASN D 4 143 ? -33.050 32.972  7.702   1.00 30.58  ? 137 ASN L N   1 
ATOM   5850 C CA  . ASN D 4 143 ? -32.746 33.761  6.516   1.00 32.98  ? 137 ASN L CA  1 
ATOM   5851 C C   . ASN D 4 143 ? -31.556 34.678  6.763   1.00 25.72  ? 137 ASN L C   1 
ATOM   5852 O O   . ASN D 4 143 ? -31.525 35.408  7.759   1.00 33.15  ? 137 ASN L O   1 
ATOM   5853 C CB  . ASN D 4 143 ? -33.964 34.587  6.090   1.00 31.58  ? 137 ASN L CB  1 
ATOM   5854 C CG  . ASN D 4 143 ? -34.035 34.791  4.589   1.00 37.94  ? 137 ASN L CG  1 
ATOM   5855 O OD1 . ASN D 4 143 ? -33.521 33.981  3.817   1.00 29.20  ? 137 ASN L OD1 1 
ATOM   5856 N ND2 . ASN D 4 143 ? -34.675 35.876  4.167   1.00 37.95  ? 137 ASN L ND2 1 
ATOM   5857 N N   . ASN D 4 144 ? -30.583 34.630  5.849   1.00 27.02  ? 138 ASN L N   1 
ATOM   5858 C CA  . ASN D 4 144 ? -29.528 35.638  5.716   1.00 30.92  ? 138 ASN L CA  1 
ATOM   5859 C C   . ASN D 4 144 ? -28.714 35.777  7.008   1.00 33.43  ? 138 ASN L C   1 
ATOM   5860 O O   . ASN D 4 144 ? -28.720 36.811  7.680   1.00 35.02  ? 138 ASN L O   1 
ATOM   5861 C CB  . ASN D 4 144 ? -30.131 36.982  5.288   1.00 34.38  ? 138 ASN L CB  1 
ATOM   5862 C CG  . ASN D 4 144 ? -30.918 36.880  3.993   1.00 32.48  ? 138 ASN L CG  1 
ATOM   5863 O OD1 . ASN D 4 144 ? -30.480 36.245  3.034   1.00 39.55  ? 138 ASN L OD1 1 
ATOM   5864 N ND2 . ASN D 4 144 ? -32.092 37.501  3.963   1.00 29.05  ? 138 ASN L ND2 1 
ATOM   5865 N N   . PHE D 4 145 ? -28.001 34.701  7.335   1.00 26.35  ? 139 PHE L N   1 
ATOM   5866 C CA  . PHE D 4 145 ? -27.168 34.663  8.529   1.00 23.83  ? 139 PHE L CA  1 
ATOM   5867 C C   . PHE D 4 145 ? -25.762 34.188  8.186   1.00 27.18  ? 139 PHE L C   1 
ATOM   5868 O O   . PHE D 4 145 ? -25.514 33.611  7.124   1.00 23.66  ? 139 PHE L O   1 
ATOM   5869 C CB  . PHE D 4 145 ? -27.768 33.755  9.612   1.00 28.06  ? 139 PHE L CB  1 
ATOM   5870 C CG  . PHE D 4 145 ? -27.892 32.314  9.202   1.00 31.25  ? 139 PHE L CG  1 
ATOM   5871 C CD1 . PHE D 4 145 ? -28.990 31.877  8.480   1.00 34.11  ? 139 PHE L CD1 1 
ATOM   5872 C CD2 . PHE D 4 145 ? -26.916 31.395  9.550   1.00 30.41  ? 139 PHE L CD2 1 
ATOM   5873 C CE1 . PHE D 4 145 ? -29.109 30.553  8.104   1.00 29.12  ? 139 PHE L CE1 1 
ATOM   5874 C CE2 . PHE D 4 145 ? -27.029 30.070  9.177   1.00 28.90  ? 139 PHE L CE2 1 
ATOM   5875 C CZ  . PHE D 4 145 ? -28.127 29.648  8.454   1.00 28.46  ? 139 PHE L CZ  1 
ATOM   5876 N N   . TYR D 4 146 ? -24.837 34.453  9.114   1.00 23.02  ? 140 TYR L N   1 
ATOM   5877 C CA  . TYR D 4 146 ? -23.462 33.978  9.043   1.00 28.20  ? 140 TYR L CA  1 
ATOM   5878 C C   . TYR D 4 146 ? -22.914 33.948  10.459  1.00 30.81  ? 140 TYR L C   1 
ATOM   5879 O O   . TYR D 4 146 ? -23.211 34.868  11.234  1.00 35.41  ? 140 TYR L O   1 
ATOM   5880 C CB  . TYR D 4 146 ? -22.591 34.873  8.152   1.00 30.53  ? 140 TYR L CB  1 
ATOM   5881 C CG  . TYR D 4 146 ? -21.172 34.370  8.003   1.00 27.60  ? 140 TYR L CG  1 
ATOM   5882 C CD1 . TYR D 4 146 ? -20.836 33.473  6.997   1.00 23.86  ? 140 TYR L CD1 1 
ATOM   5883 C CD2 . TYR D 4 146 ? -20.173 34.776  8.880   1.00 27.74  ? 140 TYR L CD2 1 
ATOM   5884 C CE1 . TYR D 4 146 ? -19.544 33.002  6.863   1.00 28.80  ? 140 TYR L CE1 1 
ATOM   5885 C CE2 . TYR D 4 146 ? -18.879 34.308  8.755   1.00 27.39  ? 140 TYR L CE2 1 
ATOM   5886 C CZ  . TYR D 4 146 ? -18.570 33.423  7.745   1.00 29.85  ? 140 TYR L CZ  1 
ATOM   5887 O OH  . TYR D 4 146 ? -17.282 32.956  7.616   1.00 35.19  ? 140 TYR L OH  1 
ATOM   5888 N N   . PRO D 4 147 ? -22.122 32.933  10.838  1.00 36.11  ? 141 PRO L N   1 
ATOM   5889 C CA  . PRO D 4 147 ? -21.655 31.784  10.043  1.00 34.08  ? 141 PRO L CA  1 
ATOM   5890 C C   . PRO D 4 147 ? -22.736 30.736  9.801   1.00 34.40  ? 141 PRO L C   1 
ATOM   5891 O O   . PRO D 4 147 ? -23.841 30.829  10.331  1.00 33.36  ? 141 PRO L O   1 
ATOM   5892 C CB  . PRO D 4 147 ? -20.503 31.231  10.892  1.00 35.05  ? 141 PRO L CB  1 
ATOM   5893 C CG  . PRO D 4 147 ? -20.896 31.561  12.296  1.00 35.94  ? 141 PRO L CG  1 
ATOM   5894 C CD  . PRO D 4 147 ? -21.562 32.910  12.202  1.00 36.80  ? 141 PRO L CD  1 
ATOM   5895 N N   . ARG D 4 148 ? -22.426 29.727  8.983   1.00 37.78  ? 142 ARG L N   1 
ATOM   5896 C CA  . ARG D 4 148 ? -23.413 28.722  8.607   1.00 31.10  ? 142 ARG L CA  1 
ATOM   5897 C C   . ARG D 4 148 ? -23.851 27.859  9.783   1.00 28.53  ? 142 ARG L C   1 
ATOM   5898 O O   . ARG D 4 148 ? -24.919 27.242  9.714   1.00 37.44  ? 142 ARG L O   1 
ATOM   5899 C CB  . ARG D 4 148 ? -22.853 27.837  7.492   1.00 29.84  ? 142 ARG L CB  1 
ATOM   5900 C CG  . ARG D 4 148 ? -23.897 27.325  6.512   1.00 35.13  ? 142 ARG L CG  1 
ATOM   5901 C CD  . ARG D 4 148 ? -24.118 25.828  6.655   1.00 48.42  ? 142 ARG L CD  1 
ATOM   5902 N NE  . ARG D 4 148 ? -22.907 25.063  6.382   1.00 45.39  ? 142 ARG L NE  1 
ATOM   5903 C CZ  . ARG D 4 148 ? -22.549 24.628  5.181   1.00 55.58  ? 142 ARG L CZ  1 
ATOM   5904 N NH1 . ARG D 4 148 ? -23.284 24.873  4.109   1.00 52.93  ? 142 ARG L NH1 1 
ATOM   5905 N NH2 . ARG D 4 148 ? -21.424 23.930  5.053   1.00 64.10  ? 142 ARG L NH2 1 
ATOM   5906 N N   . GLU D 4 149 ? -23.060 27.803  10.854  1.00 31.66  ? 143 GLU L N   1 
ATOM   5907 C CA  . GLU D 4 149 ? -23.389 26.953  11.991  1.00 33.43  ? 143 GLU L CA  1 
ATOM   5908 C C   . GLU D 4 149 ? -24.619 27.489  12.714  1.00 36.82  ? 143 GLU L C   1 
ATOM   5909 O O   . GLU D 4 149 ? -24.668 28.663  13.094  1.00 34.46  ? 143 GLU L O   1 
ATOM   5910 C CB  . GLU D 4 149 ? -22.206 26.868  12.959  1.00 33.08  ? 143 GLU L CB  1 
ATOM   5911 C CG  . GLU D 4 149 ? -20.929 26.266  12.379  1.00 51.63  ? 143 GLU L CG  1 
ATOM   5912 C CD  . GLU D 4 149 ? -20.188 27.216  11.455  1.00 53.51  ? 143 GLU L CD  1 
ATOM   5913 O OE1 . GLU D 4 149 ? -20.234 27.003  10.225  1.00 47.39  ? 143 GLU L OE1 1 
ATOM   5914 O OE2 . GLU D 4 149 ? -19.572 28.180  11.958  1.00 53.70  ? 143 GLU L OE2 1 
ATOM   5915 N N   . ALA D 4 150 ? -25.612 26.624  12.904  1.00 28.59  ? 144 ALA L N   1 
ATOM   5916 C CA  . ALA D 4 150 ? -26.849 27.008  13.568  1.00 29.65  ? 144 ALA L CA  1 
ATOM   5917 C C   . ALA D 4 150 ? -27.535 25.757  14.097  1.00 29.89  ? 144 ALA L C   1 
ATOM   5918 O O   . ALA D 4 150 ? -27.534 24.716  13.435  1.00 37.11  ? 144 ALA L O   1 
ATOM   5919 C CB  . ALA D 4 150 ? -27.782 27.766  12.617  1.00 29.17  ? 144 ALA L CB  1 
ATOM   5920 N N   . LYS D 4 151 ? -28.119 25.870  15.286  1.00 25.60  ? 145 LYS L N   1 
ATOM   5921 C CA  . LYS D 4 151 ? -28.844 24.776  15.919  1.00 30.49  ? 145 LYS L CA  1 
ATOM   5922 C C   . LYS D 4 151 ? -30.337 25.053  15.815  1.00 33.95  ? 145 LYS L C   1 
ATOM   5923 O O   . LYS D 4 151 ? -30.834 26.024  16.397  1.00 33.99  ? 145 LYS L O   1 
ATOM   5924 C CB  . LYS D 4 151 ? -28.429 24.612  17.381  1.00 37.15  ? 145 LYS L CB  1 
ATOM   5925 C CG  . LYS D 4 151 ? -28.984 23.361  18.042  1.00 33.97  ? 145 LYS L CG  1 
ATOM   5926 C CD  . LYS D 4 151 ? -28.610 23.291  19.514  1.00 37.21  ? 145 LYS L CD  1 
ATOM   5927 C CE  . LYS D 4 151 ? -29.333 24.353  20.322  1.00 45.97  ? 145 LYS L CE  1 
ATOM   5928 N NZ  . LYS D 4 151 ? -29.086 24.196  21.781  1.00 44.57  ? 145 LYS L NZ  1 
ATOM   5929 N N   . VAL D 4 152 ? -31.046 24.205  15.076  1.00 30.15  ? 146 VAL L N   1 
ATOM   5930 C CA  . VAL D 4 152 ? -32.491 24.307  14.914  1.00 26.32  ? 146 VAL L CA  1 
ATOM   5931 C C   . VAL D 4 152 ? -33.110 23.055  15.516  1.00 26.36  ? 146 VAL L C   1 
ATOM   5932 O O   . VAL D 4 152 ? -32.830 21.939  15.063  1.00 28.37  ? 146 VAL L O   1 
ATOM   5933 C CB  . VAL D 4 152 ? -32.894 24.463  13.440  1.00 23.01  ? 146 VAL L CB  1 
ATOM   5934 C CG1 . VAL D 4 152 ? -34.397 24.661  13.319  1.00 25.63  ? 146 VAL L CG1 1 
ATOM   5935 C CG2 . VAL D 4 152 ? -32.142 25.619  12.804  1.00 27.97  ? 146 VAL L CG2 1 
ATOM   5936 N N   . GLN D 4 153 ? -33.947 23.239  16.533  1.00 28.27  ? 147 GLN L N   1 
ATOM   5937 C CA  . GLN D 4 153 ? -34.580 22.129  17.227  1.00 28.19  ? 147 GLN L CA  1 
ATOM   5938 C C   . GLN D 4 153 ? -36.088 22.320  17.231  1.00 28.17  ? 147 GLN L C   1 
ATOM   5939 O O   . GLN D 4 153 ? -36.583 23.434  17.427  1.00 29.12  ? 147 GLN L O   1 
ATOM   5940 C CB  . GLN D 4 153 ? -34.061 22.000  18.662  1.00 28.23  ? 147 GLN L CB  1 
ATOM   5941 C CG  . GLN D 4 153 ? -32.572 21.723  18.740  1.00 34.42  ? 147 GLN L CG  1 
ATOM   5942 C CD  . GLN D 4 153 ? -32.138 21.240  20.106  1.00 37.12  ? 147 GLN L CD  1 
ATOM   5943 O OE1 . GLN D 4 153 ? -32.271 21.950  21.103  1.00 36.91  ? 147 GLN L OE1 1 
ATOM   5944 N NE2 . GLN D 4 153 ? -31.617 20.020  20.161  1.00 31.87  ? 147 GLN L NE2 1 
ATOM   5945 N N   . TRP D 4 154 ? -36.810 21.228  17.011  1.00 23.03  ? 148 TRP L N   1 
ATOM   5946 C CA  . TRP D 4 154 ? -38.265 21.234  17.011  1.00 29.02  ? 148 TRP L CA  1 
ATOM   5947 C C   . TRP D 4 154 ? -38.778 20.751  18.359  1.00 25.27  ? 148 TRP L C   1 
ATOM   5948 O O   . TRP D 4 154 ? -38.378 19.683  18.836  1.00 26.25  ? 148 TRP L O   1 
ATOM   5949 C CB  . TRP D 4 154 ? -38.820 20.349  15.895  1.00 28.25  ? 148 TRP L CB  1 
ATOM   5950 C CG  . TRP D 4 154 ? -38.656 20.927  14.530  1.00 25.42  ? 148 TRP L CG  1 
ATOM   5951 C CD1 . TRP D 4 154 ? -37.681 20.629  13.625  1.00 25.91  ? 148 TRP L CD1 1 
ATOM   5952 C CD2 . TRP D 4 154 ? -39.494 21.908  13.910  1.00 26.48  ? 148 TRP L CD2 1 
ATOM   5953 N NE1 . TRP D 4 154 ? -37.860 21.363  12.478  1.00 31.51  ? 148 TRP L NE1 1 
ATOM   5954 C CE2 . TRP D 4 154 ? -38.967 22.157  12.628  1.00 32.42  ? 148 TRP L CE2 1 
ATOM   5955 C CE3 . TRP D 4 154 ? -40.640 22.601  14.315  1.00 25.97  ? 148 TRP L CE3 1 
ATOM   5956 C CZ2 . TRP D 4 154 ? -39.546 23.068  11.748  1.00 26.19  ? 148 TRP L CZ2 1 
ATOM   5957 C CZ3 . TRP D 4 154 ? -41.212 23.505  13.440  1.00 28.03  ? 148 TRP L CZ3 1 
ATOM   5958 C CH2 . TRP D 4 154 ? -40.664 23.730  12.171  1.00 23.47  ? 148 TRP L CH2 1 
ATOM   5959 N N   . LYS D 4 155 ? -39.656 21.540  18.969  1.00 28.57  ? 149 LYS L N   1 
ATOM   5960 C CA  . LYS D 4 155 ? -40.347 21.155  20.190  1.00 29.63  ? 149 LYS L CA  1 
ATOM   5961 C C   . LYS D 4 155 ? -41.844 21.146  19.925  1.00 29.69  ? 149 LYS L C   1 
ATOM   5962 O O   . LYS D 4 155 ? -42.401 22.143  19.454  1.00 32.47  ? 149 LYS L O   1 
ATOM   5963 C CB  . LYS D 4 155 ? -40.009 22.103  21.343  1.00 33.75  ? 149 LYS L CB  1 
ATOM   5964 C CG  . LYS D 4 155 ? -38.639 21.863  21.959  1.00 31.08  ? 149 LYS L CG  1 
ATOM   5965 C CD  . LYS D 4 155 ? -38.381 22.810  23.120  1.00 49.04  ? 149 LYS L CD  1 
ATOM   5966 C CE  . LYS D 4 155 ? -37.150 22.396  23.915  1.00 60.59  ? 149 LYS L CE  1 
ATOM   5967 N NZ  . LYS D 4 155 ? -35.928 22.290  23.068  1.00 54.15  ? 149 LYS L NZ  1 
ATOM   5968 N N   . VAL D 4 156 ? -42.485 20.020  20.220  1.00 35.77  ? 150 VAL L N   1 
ATOM   5969 C CA  . VAL D 4 156 ? -43.926 19.859  20.070  1.00 32.41  ? 150 VAL L CA  1 
ATOM   5970 C C   . VAL D 4 156 ? -44.496 19.656  21.466  1.00 42.89  ? 150 VAL L C   1 
ATOM   5971 O O   . VAL D 4 156 ? -44.266 18.612  22.090  1.00 37.12  ? 150 VAL L O   1 
ATOM   5972 C CB  . VAL D 4 156 ? -44.280 18.687  19.146  1.00 35.99  ? 150 VAL L CB  1 
ATOM   5973 C CG1 . VAL D 4 156 ? -45.775 18.454  19.137  1.00 38.83  ? 150 VAL L CG1 1 
ATOM   5974 C CG2 . VAL D 4 156 ? -43.773 18.954  17.737  1.00 38.17  ? 150 VAL L CG2 1 
ATOM   5975 N N   . ASP D 4 157 ? -45.248 20.646  21.950  1.00 40.64  ? 151 ASP L N   1 
ATOM   5976 C CA  . ASP D 4 157 ? -45.696 20.689  23.343  1.00 43.83  ? 151 ASP L CA  1 
ATOM   5977 C C   . ASP D 4 157 ? -44.511 20.532  24.294  1.00 45.66  ? 151 ASP L C   1 
ATOM   5978 O O   . ASP D 4 157 ? -44.558 19.773  25.266  1.00 48.40  ? 151 ASP L O   1 
ATOM   5979 C CB  . ASP D 4 157 ? -46.771 19.635  23.618  1.00 38.49  ? 151 ASP L CB  1 
ATOM   5980 C CG  . ASP D 4 157 ? -48.115 19.999  23.012  1.00 55.18  ? 151 ASP L CG  1 
ATOM   5981 O OD1 . ASP D 4 157 ? -48.373 21.206  22.810  1.00 48.37  ? 151 ASP L OD1 1 
ATOM   5982 O OD2 . ASP D 4 157 ? -48.915 19.081  22.742  1.00 52.06  ? 151 ASP L OD2 1 
ATOM   5983 N N   . ASN D 4 158 ? -43.430 21.254  23.989  1.00 46.60  ? 152 ASN L N   1 
ATOM   5984 C CA  . ASN D 4 158 ? -42.204 21.264  24.789  1.00 53.19  ? 152 ASN L CA  1 
ATOM   5985 C C   . ASN D 4 158 ? -41.538 19.888  24.836  1.00 43.92  ? 152 ASN L C   1 
ATOM   5986 O O   . ASN D 4 158 ? -40.811 19.566  25.778  1.00 52.45  ? 152 ASN L O   1 
ATOM   5987 C CB  . ASN D 4 158 ? -42.471 21.791  26.204  1.00 45.08  ? 152 ASN L CB  1 
ATOM   5988 C CG  . ASN D 4 158 ? -41.201 22.198  26.925  1.00 64.14  ? 152 ASN L CG  1 
ATOM   5989 O OD1 . ASN D 4 158 ? -41.079 22.025  28.138  1.00 72.15  ? 152 ASN L OD1 1 
ATOM   5990 N ND2 . ASN D 4 158 ? -40.239 22.726  26.177  1.00 62.57  ? 152 ASN L ND2 1 
ATOM   5991 N N   . ALA D 4 159 ? -41.770 19.067  23.815  1.00 39.08  ? 153 ALA L N   1 
ATOM   5992 C CA  . ALA D 4 159 ? -41.125 17.767  23.686  1.00 30.13  ? 153 ALA L CA  1 
ATOM   5993 C C   . ALA D 4 159 ? -40.199 17.800  22.478  1.00 36.30  ? 153 ALA L C   1 
ATOM   5994 O O   . ALA D 4 159 ? -40.636 18.113  21.365  1.00 35.37  ? 153 ALA L O   1 
ATOM   5995 C CB  . ALA D 4 159 ? -42.157 16.648  23.545  1.00 26.07  ? 153 ALA L CB  1 
ATOM   5996 N N   . LEU D 4 160 ? -38.928 17.477  22.700  1.00 36.40  ? 154 LEU L N   1 
ATOM   5997 C CA  . LEU D 4 160 ? -37.940 17.518  21.632  1.00 29.15  ? 154 LEU L CA  1 
ATOM   5998 C C   . LEU D 4 160 ? -38.231 16.445  20.591  1.00 27.45  ? 154 LEU L C   1 
ATOM   5999 O O   . LEU D 4 160 ? -38.602 15.316  20.924  1.00 28.30  ? 154 LEU L O   1 
ATOM   6000 C CB  . LEU D 4 160 ? -36.536 17.334  22.207  1.00 24.16  ? 154 LEU L CB  1 
ATOM   6001 C CG  . LEU D 4 160 ? -35.354 17.518  21.255  1.00 29.72  ? 154 LEU L CG  1 
ATOM   6002 C CD1 . LEU D 4 160 ? -35.389 18.897  20.614  1.00 27.04  ? 154 LEU L CD1 1 
ATOM   6003 C CD2 . LEU D 4 160 ? -34.043 17.304  21.994  1.00 30.33  ? 154 LEU L CD2 1 
ATOM   6004 N N   . GLN D 4 161 ? -38.063 16.804  19.321  1.00 23.61  ? 155 GLN L N   1 
ATOM   6005 C CA  . GLN D 4 161 ? -38.325 15.904  18.208  1.00 21.75  ? 155 GLN L CA  1 
ATOM   6006 C C   . GLN D 4 161 ? -37.020 15.320  17.687  1.00 20.89  ? 155 GLN L C   1 
ATOM   6007 O O   . GLN D 4 161 ? -35.985 15.993  17.676  1.00 23.33  ? 155 GLN L O   1 
ATOM   6008 C CB  . GLN D 4 161 ? -39.059 16.631  17.080  1.00 24.10  ? 155 GLN L CB  1 
ATOM   6009 C CG  . GLN D 4 161 ? -40.421 17.167  17.481  1.00 32.64  ? 155 GLN L CG  1 
ATOM   6010 C CD  . GLN D 4 161 ? -41.360 16.074  17.949  1.00 28.67  ? 155 GLN L CD  1 
ATOM   6011 O OE1 . GLN D 4 161 ? -41.623 15.113  17.225  1.00 27.32  ? 155 GLN L OE1 1 
ATOM   6012 N NE2 . GLN D 4 161 ? -41.865 16.210  19.170  1.00 26.53  ? 155 GLN L NE2 1 
ATOM   6013 N N   . SER D 4 162 ? -37.074 14.061  17.258  1.00 25.38  ? 156 SER L N   1 
ATOM   6014 C CA  . SER D 4 162 ? -35.896 13.362  16.765  1.00 21.86  ? 156 SER L CA  1 
ATOM   6015 C C   . SER D 4 162 ? -36.272 12.503  15.569  1.00 20.68  ? 156 SER L C   1 
ATOM   6016 O O   . SER D 4 162 ? -37.254 11.757  15.621  1.00 18.80  ? 156 SER L O   1 
ATOM   6017 C CB  . SER D 4 162 ? -35.274 12.492  17.864  1.00 20.87  ? 156 SER L CB  1 
ATOM   6018 O OG  . SER D 4 162 ? -34.185 11.737  17.362  1.00 21.02  ? 156 SER L OG  1 
ATOM   6019 N N   . GLY D 4 163 ? -35.493 12.618  14.493  1.00 22.25  ? 157 GLY L N   1 
ATOM   6020 C CA  . GLY D 4 163 ? -35.617 11.743  13.347  1.00 17.40  ? 157 GLY L CA  1 
ATOM   6021 C C   . GLY D 4 163 ? -36.684 12.114  12.341  1.00 23.81  ? 157 GLY L C   1 
ATOM   6022 O O   . GLY D 4 163 ? -36.725 11.510  11.261  1.00 25.37  ? 157 GLY L O   1 
ATOM   6023 N N   . ASN D 4 164 ? -37.547 13.084  12.643  1.00 20.47  ? 158 ASN L N   1 
ATOM   6024 C CA  . ASN D 4 164 ? -38.636 13.457  11.749  1.00 22.61  ? 158 ASN L CA  1 
ATOM   6025 C C   . ASN D 4 164 ? -38.441 14.840  11.135  1.00 21.32  ? 158 ASN L C   1 
ATOM   6026 O O   . ASN D 4 164 ? -39.420 15.478  10.736  1.00 24.06  ? 158 ASN L O   1 
ATOM   6027 C CB  . ASN D 4 164 ? -39.975 13.386  12.485  1.00 18.08  ? 158 ASN L CB  1 
ATOM   6028 C CG  . ASN D 4 164 ? -39.963 14.151  13.792  1.00 22.41  ? 158 ASN L CG  1 
ATOM   6029 O OD1 . ASN D 4 164 ? -38.996 14.842  14.112  1.00 23.99  ? 158 ASN L OD1 1 
ATOM   6030 N ND2 . ASN D 4 164 ? -41.044 14.035  14.555  1.00 26.08  ? 158 ASN L ND2 1 
ATOM   6031 N N   . SER D 4 165 ? -37.201 15.316  11.050  1.00 16.33  ? 159 SER L N   1 
ATOM   6032 C CA  . SER D 4 165 ? -36.917 16.616  10.461  1.00 19.78  ? 159 SER L CA  1 
ATOM   6033 C C   . SER D 4 165 ? -35.719 16.508  9.528   1.00 25.20  ? 159 SER L C   1 
ATOM   6034 O O   . SER D 4 165 ? -34.798 15.722  9.762   1.00 22.24  ? 159 SER L O   1 
ATOM   6035 C CB  . SER D 4 165 ? -36.647 17.679  11.533  1.00 18.07  ? 159 SER L CB  1 
ATOM   6036 O OG  . SER D 4 165 ? -35.521 17.334  12.320  1.00 35.18  ? 159 SER L OG  1 
ATOM   6037 N N   . GLN D 4 166 ? -35.746 17.310  8.466   1.00 24.20  ? 160 GLN L N   1 
ATOM   6038 C CA  . GLN D 4 166 ? -34.643 17.410  7.522   1.00 24.10  ? 160 GLN L CA  1 
ATOM   6039 C C   . GLN D 4 166 ? -34.319 18.877  7.284   1.00 22.28  ? 160 GLN L C   1 
ATOM   6040 O O   . GLN D 4 166 ? -35.223 19.714  7.190   1.00 20.94  ? 160 GLN L O   1 
ATOM   6041 C CB  . GLN D 4 166 ? -34.973 16.722  6.191   1.00 19.97  ? 160 GLN L CB  1 
ATOM   6042 C CG  . GLN D 4 166 ? -35.231 15.229  6.308   1.00 31.53  ? 160 GLN L CG  1 
ATOM   6043 C CD  . GLN D 4 166 ? -35.366 14.553  4.957   1.00 46.06  ? 160 GLN L CD  1 
ATOM   6044 O OE1 . GLN D 4 166 ? -36.472 14.374  4.446   1.00 45.64  ? 160 GLN L OE1 1 
ATOM   6045 N NE2 . GLN D 4 166 ? -34.236 14.173  4.371   1.00 36.50  ? 160 GLN L NE2 1 
ATOM   6046 N N   . GLU D 4 167 ? -33.030 19.184  7.183   1.00 21.16  ? 161 GLU L N   1 
ATOM   6047 C CA  . GLU D 4 167 ? -32.561 20.545  6.986   1.00 18.62  ? 161 GLU L CA  1 
ATOM   6048 C C   . GLU D 4 167 ? -31.954 20.704  5.599   1.00 19.15  ? 161 GLU L C   1 
ATOM   6049 O O   . GLU D 4 167 ? -31.364 19.771  5.048   1.00 19.90  ? 161 GLU L O   1 
ATOM   6050 C CB  . GLU D 4 167 ? -31.526 20.936  8.045   1.00 19.22  ? 161 GLU L CB  1 
ATOM   6051 C CG  . GLU D 4 167 ? -32.072 21.002  9.460   1.00 26.61  ? 161 GLU L CG  1 
ATOM   6052 C CD  . GLU D 4 167 ? -31.057 21.545  10.447  1.00 40.64  ? 161 GLU L CD  1 
ATOM   6053 O OE1 . GLU D 4 167 ? -29.926 21.864  10.022  1.00 36.28  ? 161 GLU L OE1 1 
ATOM   6054 O OE2 . GLU D 4 167 ? -31.390 21.654  11.646  1.00 40.21  ? 161 GLU L OE2 1 
ATOM   6055 N N   . SER D 4 168 ? -32.116 21.900  5.037   1.00 22.60  ? 162 SER L N   1 
ATOM   6056 C CA  . SER D 4 168 ? -31.514 22.254  3.762   1.00 22.14  ? 162 SER L CA  1 
ATOM   6057 C C   . SER D 4 168 ? -30.930 23.654  3.868   1.00 24.60  ? 162 SER L C   1 
ATOM   6058 O O   . SER D 4 168 ? -31.545 24.548  4.458   1.00 21.94  ? 162 SER L O   1 
ATOM   6059 C CB  . SER D 4 168 ? -32.536 22.188  2.620   1.00 25.25  ? 162 SER L CB  1 
ATOM   6060 O OG  . SER D 4 168 ? -31.896 22.291  1.359   1.00 29.93  ? 162 SER L OG  1 
ATOM   6061 N N   . VAL D 4 169 ? -29.743 23.841  3.299   1.00 24.76  ? 163 VAL L N   1 
ATOM   6062 C CA  . VAL D 4 169 ? -29.019 25.103  3.388   1.00 23.11  ? 163 VAL L CA  1 
ATOM   6063 C C   . VAL D 4 169 ? -28.609 25.540  1.989   1.00 23.20  ? 163 VAL L C   1 
ATOM   6064 O O   . VAL D 4 169 ? -28.149 24.726  1.180   1.00 24.33  ? 163 VAL L O   1 
ATOM   6065 C CB  . VAL D 4 169 ? -27.790 24.988  4.319   1.00 24.19  ? 163 VAL L CB  1 
ATOM   6066 C CG1 . VAL D 4 169 ? -26.880 23.844  3.885   1.00 27.68  ? 163 VAL L CG1 1 
ATOM   6067 C CG2 . VAL D 4 169 ? -27.025 26.303  4.368   1.00 20.11  ? 163 VAL L CG2 1 
ATOM   6068 N N   . THR D 4 170 ? -28.798 26.825  1.698   1.00 28.03  ? 164 THR L N   1 
ATOM   6069 C CA  . THR D 4 170 ? -28.379 27.380  0.422   1.00 24.98  ? 164 THR L CA  1 
ATOM   6070 C C   . THR D 4 170 ? -26.862 27.549  0.388   1.00 33.20  ? 164 THR L C   1 
ATOM   6071 O O   . THR D 4 170 ? -26.171 27.459  1.407   1.00 25.69  ? 164 THR L O   1 
ATOM   6072 C CB  . THR D 4 170 ? -29.053 28.729  0.173   1.00 27.47  ? 164 THR L CB  1 
ATOM   6073 O OG1 . THR D 4 170 ? -28.613 29.671  1.160   1.00 25.17  ? 164 THR L OG1 1 
ATOM   6074 C CG2 . THR D 4 170 ? -30.565 28.596  0.247   1.00 25.42  ? 164 THR L CG2 1 
ATOM   6075 N N   . GLU D 4 171 ? -26.340 27.789  -0.810  1.00 36.00  ? 165 GLU L N   1 
ATOM   6076 C CA  . GLU D 4 171 ? -24.945 28.176  -0.925  1.00 36.65  ? 165 GLU L CA  1 
ATOM   6077 C C   . GLU D 4 171 ? -24.770 29.629  -0.495  1.00 35.17  ? 165 GLU L C   1 
ATOM   6078 O O   . GLU D 4 171 ? -25.731 30.400  -0.408  1.00 32.72  ? 165 GLU L O   1 
ATOM   6079 C CB  . GLU D 4 171 ? -24.439 27.978  -2.355  1.00 32.98  ? 165 GLU L CB  1 
ATOM   6080 C CG  . GLU D 4 171 ? -24.368 26.522  -2.805  1.00 56.41  ? 165 GLU L CG  1 
ATOM   6081 C CD  . GLU D 4 171 ? -23.226 25.743  -2.162  1.00 54.63  ? 165 GLU L CD  1 
ATOM   6082 O OE1 . GLU D 4 171 ? -22.569 26.278  -1.241  1.00 48.00  ? 165 GLU L OE1 1 
ATOM   6083 O OE2 . GLU D 4 171 ? -22.976 24.595  -2.583  1.00 55.76  ? 165 GLU L OE2 1 
ATOM   6084 N N   . GLN D 4 172 ? -23.522 29.997  -0.221  1.00 30.88  ? 166 GLN L N   1 
ATOM   6085 C CA  . GLN D 4 172 ? -23.225 31.344  0.247   1.00 26.35  ? 166 GLN L CA  1 
ATOM   6086 C C   . GLN D 4 172 ? -23.552 32.366  -0.835  1.00 30.10  ? 166 GLN L C   1 
ATOM   6087 O O   . GLN D 4 172 ? -23.178 32.195  -2.000  1.00 25.91  ? 166 GLN L O   1 
ATOM   6088 C CB  . GLN D 4 172 ? -21.757 31.450  0.653   1.00 25.96  ? 166 GLN L CB  1 
ATOM   6089 C CG  . GLN D 4 172 ? -21.431 32.690  1.462   1.00 27.69  ? 166 GLN L CG  1 
ATOM   6090 C CD  . GLN D 4 172 ? -19.979 32.742  1.891   1.00 23.31  ? 166 GLN L CD  1 
ATOM   6091 O OE1 . GLN D 4 172 ? -19.086 32.322  1.156   1.00 33.95  ? 166 GLN L OE1 1 
ATOM   6092 N NE2 . GLN D 4 172 ? -19.736 33.256  3.091   1.00 23.15  ? 166 GLN L NE2 1 
ATOM   6093 N N   . ASP D 4 173 ? -24.251 33.429  -0.448  1.00 30.29  ? 167 ASP L N   1 
ATOM   6094 C CA  . ASP D 4 173 ? -24.620 34.471  -1.396  1.00 33.93  ? 167 ASP L CA  1 
ATOM   6095 C C   . ASP D 4 173 ? -23.378 35.204  -1.889  1.00 42.83  ? 167 ASP L C   1 
ATOM   6096 O O   . ASP D 4 173 ? -22.440 35.455  -1.128  1.00 42.57  ? 167 ASP L O   1 
ATOM   6097 C CB  . ASP D 4 173 ? -25.596 35.454  -0.751  1.00 41.21  ? 167 ASP L CB  1 
ATOM   6098 C CG  . ASP D 4 173 ? -26.091 36.506  -1.723  1.00 50.02  ? 167 ASP L CG  1 
ATOM   6099 O OD1 . ASP D 4 173 ? -26.952 36.180  -2.569  1.00 53.31  ? 167 ASP L OD1 1 
ATOM   6100 O OD2 . ASP D 4 173 ? -25.619 37.660  -1.642  1.00 48.57  ? 167 ASP L OD2 1 
ATOM   6101 N N   . SER D 4 174 ? -23.374 35.545  -3.178  1.00 46.71  ? 168 SER L N   1 
ATOM   6102 C CA  . SER D 4 174 ? -22.197 36.165  -3.776  1.00 43.96  ? 168 SER L CA  1 
ATOM   6103 C C   . SER D 4 174 ? -22.035 37.626  -3.375  1.00 46.34  ? 168 SER L C   1 
ATOM   6104 O O   . SER D 4 174 ? -20.944 38.181  -3.544  1.00 51.82  ? 168 SER L O   1 
ATOM   6105 C CB  . SER D 4 174 ? -22.261 36.046  -5.299  1.00 53.43  ? 168 SER L CB  1 
ATOM   6106 O OG  . SER D 4 174 ? -21.080 36.548  -5.901  1.00 87.89  ? 168 SER L OG  1 
ATOM   6107 N N   . LYS D 4 175 ? -23.084 38.260  -2.849  1.00 54.40  ? 169 LYS L N   1 
ATOM   6108 C CA  . LYS D 4 175 ? -23.043 39.682  -2.517  1.00 48.66  ? 169 LYS L CA  1 
ATOM   6109 C C   . LYS D 4 175 ? -22.807 39.929  -1.029  1.00 46.59  ? 169 LYS L C   1 
ATOM   6110 O O   . LYS D 4 175 ? -21.833 40.588  -0.656  1.00 53.44  ? 169 LYS L O   1 
ATOM   6111 C CB  . LYS D 4 175 ? -24.340 40.359  -2.978  1.00 57.14  ? 169 LYS L CB  1 
ATOM   6112 C CG  . LYS D 4 175 ? -24.352 40.719  -4.456  1.00 52.01  ? 169 LYS L CG  1 
ATOM   6113 C CD  . LYS D 4 175 ? -25.761 40.686  -5.025  1.00 65.78  ? 169 LYS L CD  1 
ATOM   6114 C CE  . LYS D 4 175 ? -25.805 41.264  -6.431  1.00 68.47  ? 169 LYS L CE  1 
ATOM   6115 N NZ  . LYS D 4 175 ? -25.595 42.739  -6.427  1.00 73.16  ? 169 LYS L NZ  1 
ATOM   6116 N N   . ASP D 4 176 ? -23.682 39.411  -0.168  1.00 42.36  ? 170 ASP L N   1 
ATOM   6117 C CA  . ASP D 4 176 ? -23.573 39.642  1.267   1.00 42.11  ? 170 ASP L CA  1 
ATOM   6118 C C   . ASP D 4 176 ? -22.952 38.472  2.021   1.00 43.65  ? 170 ASP L C   1 
ATOM   6119 O O   . ASP D 4 176 ? -22.822 38.549  3.246   1.00 29.27  ? 170 ASP L O   1 
ATOM   6120 C CB  . ASP D 4 176 ? -24.947 39.972  1.860   1.00 42.32  ? 170 ASP L CB  1 
ATOM   6121 C CG  . ASP D 4 176 ? -26.048 39.084  1.318   1.00 57.26  ? 170 ASP L CG  1 
ATOM   6122 O OD1 . ASP D 4 176 ? -25.902 37.846  1.386   1.00 56.58  ? 170 ASP L OD1 1 
ATOM   6123 O OD2 . ASP D 4 176 ? -27.064 39.625  0.833   1.00 66.81  ? 170 ASP L OD2 1 
ATOM   6124 N N   . SER D 4 177 ? -22.569 37.401  1.322   1.00 37.96  ? 171 SER L N   1 
ATOM   6125 C CA  . SER D 4 177 ? -21.859 36.268  1.924   1.00 36.87  ? 171 SER L CA  1 
ATOM   6126 C C   . SER D 4 177 ? -22.642 35.651  3.083   1.00 28.38  ? 171 SER L C   1 
ATOM   6127 O O   . SER D 4 177 ? -22.070 35.256  4.101   1.00 34.32  ? 171 SER L O   1 
ATOM   6128 C CB  . SER D 4 177 ? -20.456 36.678  2.379   1.00 27.09  ? 171 SER L CB  1 
ATOM   6129 O OG  . SER D 4 177 ? -19.698 37.194  1.298   1.00 38.42  ? 171 SER L OG  1 
ATOM   6130 N N   . THR D 4 178 ? -23.959 35.558  2.928   1.00 24.58  ? 172 THR L N   1 
ATOM   6131 C CA  . THR D 4 178 ? -24.830 35.004  3.954   1.00 28.10  ? 172 THR L CA  1 
ATOM   6132 C C   . THR D 4 178 ? -25.405 33.666  3.508   1.00 29.54  ? 172 THR L C   1 
ATOM   6133 O O   . THR D 4 178 ? -25.306 33.266  2.345   1.00 26.02  ? 172 THR L O   1 
ATOM   6134 C CB  . THR D 4 178 ? -25.969 35.971  4.293   1.00 27.55  ? 172 THR L CB  1 
ATOM   6135 O OG1 . THR D 4 178 ? -26.703 36.285  3.103   1.00 29.57  ? 172 THR L OG1 1 
ATOM   6136 C CG2 . THR D 4 178 ? -25.416 37.244  4.895   1.00 25.88  ? 172 THR L CG2 1 
ATOM   6137 N N   . TYR D 4 179 ? -26.026 32.981  4.463   1.00 30.66  ? 173 TYR L N   1 
ATOM   6138 C CA  . TYR D 4 179 ? -26.654 31.690  4.241   1.00 25.01  ? 173 TYR L CA  1 
ATOM   6139 C C   . TYR D 4 179 ? -28.124 31.751  4.632   1.00 25.71  ? 173 TYR L C   1 
ATOM   6140 O O   . TYR D 4 179 ? -28.546 32.600  5.422   1.00 30.55  ? 173 TYR L O   1 
ATOM   6141 C CB  . TYR D 4 179 ? -25.962 30.582  5.046   1.00 25.02  ? 173 TYR L CB  1 
ATOM   6142 C CG  . TYR D 4 179 ? -24.554 30.265  4.601   1.00 32.39  ? 173 TYR L CG  1 
ATOM   6143 C CD1 . TYR D 4 179 ? -24.322 29.464  3.490   1.00 21.20  ? 173 TYR L CD1 1 
ATOM   6144 C CD2 . TYR D 4 179 ? -23.457 30.751  5.300   1.00 20.43  ? 173 TYR L CD2 1 
ATOM   6145 C CE1 . TYR D 4 179 ? -23.038 29.164  3.083   1.00 21.00  ? 173 TYR L CE1 1 
ATOM   6146 C CE2 . TYR D 4 179 ? -22.169 30.456  4.900   1.00 26.99  ? 173 TYR L CE2 1 
ATOM   6147 C CZ  . TYR D 4 179 ? -21.965 29.662  3.790   1.00 26.25  ? 173 TYR L CZ  1 
ATOM   6148 O OH  . TYR D 4 179 ? -20.684 29.366  3.385   1.00 29.54  ? 173 TYR L OH  1 
ATOM   6149 N N   . SER D 4 180 ? -28.901 30.837  4.059   1.00 26.36  ? 174 SER L N   1 
ATOM   6150 C CA  . SER D 4 180 ? -30.291 30.630  4.436   1.00 24.46  ? 174 SER L CA  1 
ATOM   6151 C C   . SER D 4 180 ? -30.522 29.145  4.664   1.00 28.76  ? 174 SER L C   1 
ATOM   6152 O O   . SER D 4 180 ? -30.016 28.308  3.910   1.00 33.57  ? 174 SER L O   1 
ATOM   6153 C CB  . SER D 4 180 ? -31.252 31.163  3.367   1.00 24.30  ? 174 SER L CB  1 
ATOM   6154 O OG  . SER D 4 180 ? -31.235 32.579  3.329   1.00 29.76  ? 174 SER L OG  1 
ATOM   6155 N N   . LEU D 4 181 ? -31.285 28.822  5.706   1.00 26.86  ? 175 LEU L N   1 
ATOM   6156 C CA  . LEU D 4 181 ? -31.521 27.441  6.102   1.00 22.16  ? 175 LEU L CA  1 
ATOM   6157 C C   . LEU D 4 181 ? -33.011 27.209  6.294   1.00 23.38  ? 175 LEU L C   1 
ATOM   6158 O O   . LEU D 4 181 ? -33.729 28.087  6.782   1.00 23.55  ? 175 LEU L O   1 
ATOM   6159 C CB  . LEU D 4 181 ? -30.757 27.099  7.394   1.00 22.56  ? 175 LEU L CB  1 
ATOM   6160 C CG  . LEU D 4 181 ? -30.791 25.656  7.905   1.00 23.66  ? 175 LEU L CG  1 
ATOM   6161 C CD1 . LEU D 4 181 ? -29.452 25.291  8.521   1.00 21.96  ? 175 LEU L CD1 1 
ATOM   6162 C CD2 . LEU D 4 181 ? -31.909 25.451  8.918   1.00 18.22  ? 175 LEU L CD2 1 
ATOM   6163 N N   . SER D 4 182 ? -33.468 26.021  5.906   1.00 17.90  ? 176 SER L N   1 
ATOM   6164 C CA  . SER D 4 182 ? -34.848 25.603  6.105   1.00 22.54  ? 176 SER L CA  1 
ATOM   6165 C C   . SER D 4 182 ? -34.857 24.273  6.841   1.00 23.58  ? 176 SER L C   1 
ATOM   6166 O O   . SER D 4 182 ? -34.114 23.355  6.480   1.00 26.17  ? 176 SER L O   1 
ATOM   6167 C CB  . SER D 4 182 ? -35.590 25.476  4.770   1.00 23.91  ? 176 SER L CB  1 
ATOM   6168 O OG  . SER D 4 182 ? -35.102 24.380  4.015   1.00 27.84  ? 176 SER L OG  1 
ATOM   6169 N N   . SER D 4 183 ? -35.686 24.173  7.876   1.00 20.62  ? 177 SER L N   1 
ATOM   6170 C CA  . SER D 4 183 ? -35.893 22.929  8.603   1.00 18.30  ? 177 SER L CA  1 
ATOM   6171 C C   . SER D 4 183 ? -37.355 22.533  8.470   1.00 20.28  ? 177 SER L C   1 
ATOM   6172 O O   . SER D 4 183 ? -38.247 23.336  8.762   1.00 30.08  ? 177 SER L O   1 
ATOM   6173 C CB  . SER D 4 183 ? -35.507 23.074  10.078  1.00 28.40  ? 177 SER L CB  1 
ATOM   6174 O OG  . SER D 4 183 ? -35.672 21.847  10.769  1.00 29.26  ? 177 SER L OG  1 
ATOM   6175 N N   . THR D 4 184 ? -37.597 21.301  8.029   1.00 19.66  ? 178 THR L N   1 
ATOM   6176 C CA  . THR D 4 184 ? -38.944 20.816  7.756   1.00 20.24  ? 178 THR L CA  1 
ATOM   6177 C C   . THR D 4 184 ? -39.262 19.660  8.692   1.00 29.19  ? 178 THR L C   1 
ATOM   6178 O O   . THR D 4 184 ? -38.567 18.639  8.680   1.00 27.08  ? 178 THR L O   1 
ATOM   6179 C CB  . THR D 4 184 ? -39.084 20.375  6.297   1.00 28.72  ? 178 THR L CB  1 
ATOM   6180 O OG1 . THR D 4 184 ? -38.762 21.471  5.432   1.00 24.67  ? 178 THR L OG1 1 
ATOM   6181 C CG2 . THR D 4 184 ? -40.506 19.915  6.016   1.00 27.12  ? 178 THR L CG2 1 
ATOM   6182 N N   . LEU D 4 185 ? -40.316 19.818  9.487   1.00 29.93  ? 179 LEU L N   1 
ATOM   6183 C CA  . LEU D 4 185 ? -40.802 18.774  10.380  1.00 23.20  ? 179 LEU L CA  1 
ATOM   6184 C C   . LEU D 4 185 ? -41.982 18.076  9.716   1.00 22.94  ? 179 LEU L C   1 
ATOM   6185 O O   . LEU D 4 185 ? -43.001 18.712  9.430   1.00 23.73  ? 179 LEU L O   1 
ATOM   6186 C CB  . LEU D 4 185 ? -41.213 19.363  11.730  1.00 26.66  ? 179 LEU L CB  1 
ATOM   6187 C CG  . LEU D 4 185 ? -41.805 18.404  12.766  1.00 20.58  ? 179 LEU L CG  1 
ATOM   6188 C CD1 . LEU D 4 185 ? -40.720 17.544  13.394  1.00 22.40  ? 179 LEU L CD1 1 
ATOM   6189 C CD2 . LEU D 4 185 ? -42.571 19.172  13.831  1.00 16.96  ? 179 LEU L CD2 1 
ATOM   6190 N N   . THR D 4 186 ? -41.844 16.775  9.476   1.00 24.06  ? 180 THR L N   1 
ATOM   6191 C CA  . THR D 4 186 ? -42.866 15.987  8.800   1.00 34.24  ? 180 THR L CA  1 
ATOM   6192 C C   . THR D 4 186 ? -43.544 15.059  9.797   1.00 33.83  ? 180 THR L C   1 
ATOM   6193 O O   . THR D 4 186 ? -42.875 14.274  10.478  1.00 32.45  ? 180 THR L O   1 
ATOM   6194 C CB  . THR D 4 186 ? -42.269 15.173  7.651   1.00 46.76  ? 180 THR L CB  1 
ATOM   6195 O OG1 . THR D 4 186 ? -41.759 16.060  6.648   1.00 44.81  ? 180 THR L OG1 1 
ATOM   6196 C CG2 . THR D 4 186 ? -43.329 14.272  7.034   1.00 44.98  ? 180 THR L CG2 1 
ATOM   6197 N N   . LEU D 4 187 ? -44.868 15.153  9.876   1.00 31.12  ? 181 LEU L N   1 
ATOM   6198 C CA  . LEU D 4 187 ? -45.660 14.328  10.772  1.00 33.25  ? 181 LEU L CA  1 
ATOM   6199 C C   . LEU D 4 187 ? -46.885 13.818  10.030  1.00 35.84  ? 181 LEU L C   1 
ATOM   6200 O O   . LEU D 4 187 ? -47.340 14.419  9.054   1.00 40.01  ? 181 LEU L O   1 
ATOM   6201 C CB  . LEU D 4 187 ? -46.094 15.104  12.024  1.00 32.56  ? 181 LEU L CB  1 
ATOM   6202 C CG  . LEU D 4 187 ? -45.003 15.533  13.006  1.00 33.31  ? 181 LEU L CG  1 
ATOM   6203 C CD1 . LEU D 4 187 ? -45.594 16.402  14.103  1.00 32.26  ? 181 LEU L CD1 1 
ATOM   6204 C CD2 . LEU D 4 187 ? -44.314 14.316  13.599  1.00 35.08  ? 181 LEU L CD2 1 
ATOM   6205 N N   . SER D 4 188 ? -47.413 12.693  10.501  1.00 38.15  ? 182 SER L N   1 
ATOM   6206 C CA  . SER D 4 188 ? -48.680 12.204  9.985   1.00 36.36  ? 182 SER L CA  1 
ATOM   6207 C C   . SER D 4 188 ? -49.812 13.118  10.445  1.00 39.93  ? 182 SER L C   1 
ATOM   6208 O O   . SER D 4 188 ? -49.683 13.872  11.414  1.00 47.66  ? 182 SER L O   1 
ATOM   6209 C CB  . SER D 4 188 ? -48.939 10.772  10.451  1.00 38.02  ? 182 SER L CB  1 
ATOM   6210 O OG  . SER D 4 188 ? -49.233 10.732  11.837  1.00 43.66  ? 182 SER L OG  1 
ATOM   6211 N N   . LYS D 4 189 ? -50.933 13.052  9.725   1.00 43.93  ? 183 LYS L N   1 
ATOM   6212 C CA  . LYS D 4 189 ? -52.087 13.859  10.106  1.00 38.70  ? 183 LYS L CA  1 
ATOM   6213 C C   . LYS D 4 189 ? -52.578 13.488  11.499  1.00 40.81  ? 183 LYS L C   1 
ATOM   6214 O O   . LYS D 4 189 ? -52.917 14.366  12.300  1.00 44.52  ? 183 LYS L O   1 
ATOM   6215 C CB  . LYS D 4 189 ? -53.207 13.698  9.078   1.00 47.23  ? 183 LYS L CB  1 
ATOM   6216 C CG  . LYS D 4 189 ? -54.472 14.468  9.416   1.00 49.94  ? 183 LYS L CG  1 
ATOM   6217 C CD  . LYS D 4 189 ? -55.527 14.299  8.336   1.00 53.21  ? 183 LYS L CD  1 
ATOM   6218 C CE  . LYS D 4 189 ? -56.863 14.870  8.778   1.00 62.05  ? 183 LYS L CE  1 
ATOM   6219 N NZ  . LYS D 4 189 ? -57.395 14.150  9.968   1.00 76.26  ? 183 LYS L NZ  1 
ATOM   6220 N N   . ALA D 4 190 ? -52.612 12.189  11.810  1.00 42.64  ? 184 ALA L N   1 
ATOM   6221 C CA  . ALA D 4 190 ? -53.042 11.757  13.136  1.00 46.03  ? 184 ALA L CA  1 
ATOM   6222 C C   . ALA D 4 190 ? -52.107 12.278  14.221  1.00 43.93  ? 184 ALA L C   1 
ATOM   6223 O O   . ALA D 4 190 ? -52.564 12.766  15.261  1.00 50.11  ? 184 ALA L O   1 
ATOM   6224 C CB  . ALA D 4 190 ? -53.130 10.232  13.189  1.00 44.02  ? 184 ALA L CB  1 
ATOM   6225 N N   . ASP D 4 191 ? -50.793 12.188  13.996  1.00 51.31  ? 185 ASP L N   1 
ATOM   6226 C CA  . ASP D 4 191 ? -49.840 12.699  14.978  1.00 47.80  ? 185 ASP L CA  1 
ATOM   6227 C C   . ASP D 4 191 ? -49.912 14.214  15.099  1.00 35.13  ? 185 ASP L C   1 
ATOM   6228 O O   . ASP D 4 191 ? -49.668 14.760  16.181  1.00 41.54  ? 185 ASP L O   1 
ATOM   6229 C CB  . ASP D 4 191 ? -48.417 12.274  14.613  1.00 51.87  ? 185 ASP L CB  1 
ATOM   6230 C CG  . ASP D 4 191 ? -48.132 10.825  14.953  1.00 56.29  ? 185 ASP L CG  1 
ATOM   6231 O OD1 . ASP D 4 191 ? -48.793 10.285  15.865  1.00 56.79  ? 185 ASP L OD1 1 
ATOM   6232 O OD2 . ASP D 4 191 ? -47.241 10.227  14.313  1.00 51.99  ? 185 ASP L OD2 1 
ATOM   6233 N N   . TYR D 4 192 ? -50.238 14.907  14.006  1.00 42.16  ? 186 TYR L N   1 
ATOM   6234 C CA  . TYR D 4 192 ? -50.252 16.366  14.027  1.00 40.16  ? 186 TYR L CA  1 
ATOM   6235 C C   . TYR D 4 192 ? -51.389 16.917  14.877  1.00 37.43  ? 186 TYR L C   1 
ATOM   6236 O O   . TYR D 4 192 ? -51.236 17.973  15.501  1.00 40.72  ? 186 TYR L O   1 
ATOM   6237 C CB  . TYR D 4 192 ? -50.347 16.908  12.601  1.00 38.08  ? 186 TYR L CB  1 
ATOM   6238 C CG  . TYR D 4 192 ? -50.520 18.408  12.529  1.00 35.98  ? 186 TYR L CG  1 
ATOM   6239 C CD1 . TYR D 4 192 ? -49.479 19.263  12.869  1.00 28.09  ? 186 TYR L CD1 1 
ATOM   6240 C CD2 . TYR D 4 192 ? -51.722 18.969  12.118  1.00 33.69  ? 186 TYR L CD2 1 
ATOM   6241 C CE1 . TYR D 4 192 ? -49.633 20.636  12.805  1.00 36.87  ? 186 TYR L CE1 1 
ATOM   6242 C CE2 . TYR D 4 192 ? -51.885 20.340  12.050  1.00 33.50  ? 186 TYR L CE2 1 
ATOM   6243 C CZ  . TYR D 4 192 ? -50.837 21.168  12.395  1.00 34.07  ? 186 TYR L CZ  1 
ATOM   6244 O OH  . TYR D 4 192 ? -50.993 22.533  12.328  1.00 30.70  ? 186 TYR L OH  1 
ATOM   6245 N N   . GLU D 4 193 ? -52.525 16.228  14.918  1.00 45.44  ? 187 GLU L N   1 
ATOM   6246 C CA  . GLU D 4 193 ? -53.717 16.741  15.580  1.00 53.90  ? 187 GLU L CA  1 
ATOM   6247 C C   . GLU D 4 193 ? -53.829 16.309  17.036  1.00 49.38  ? 187 GLU L C   1 
ATOM   6248 O O   . GLU D 4 193 ? -54.806 16.670  17.699  1.00 54.73  ? 187 GLU L O   1 
ATOM   6249 C CB  . GLU D 4 193 ? -54.964 16.311  14.802  1.00 55.96  ? 187 GLU L CB  1 
ATOM   6250 C CG  . GLU D 4 193 ? -54.838 16.619  13.319  1.00 60.31  ? 187 GLU L CG  1 
ATOM   6251 C CD  . GLU D 4 193 ? -56.144 16.515  12.561  1.00 68.14  ? 187 GLU L CD  1 
ATOM   6252 O OE1 . GLU D 4 193 ? -56.917 15.569  12.814  1.00 77.29  ? 187 GLU L OE1 1 
ATOM   6253 O OE2 . GLU D 4 193 ? -56.393 17.389  11.702  1.00 87.57  ? 187 GLU L OE2 1 
ATOM   6254 N N   . LYS D 4 194 ? -52.858 15.558  17.547  1.00 44.83  ? 188 LYS L N   1 
ATOM   6255 C CA  . LYS D 4 194 ? -52.813 15.194  18.957  1.00 49.21  ? 188 LYS L CA  1 
ATOM   6256 C C   . LYS D 4 194 ? -52.066 16.213  19.807  1.00 44.71  ? 188 LYS L C   1 
ATOM   6257 O O   . LYS D 4 194 ? -51.992 16.044  21.029  1.00 53.38  ? 188 LYS L O   1 
ATOM   6258 C CB  . LYS D 4 194 ? -52.170 13.813  19.125  1.00 48.78  ? 188 LYS L CB  1 
ATOM   6259 C CG  . LYS D 4 194 ? -53.170 12.673  19.232  1.00 55.47  ? 188 LYS L CG  1 
ATOM   6260 C CD  . LYS D 4 194 ? -52.865 11.568  18.235  1.00 53.57  ? 188 LYS L CD  1 
ATOM   6261 C CE  . LYS D 4 194 ? -51.455 11.030  18.411  1.00 46.57  ? 188 LYS L CE  1 
ATOM   6262 N NZ  . LYS D 4 194 ? -51.143 9.973   17.411  1.00 52.97  ? 188 LYS L NZ  1 
ATOM   6263 N N   . HIS D 4 195 ? -51.516 17.261  19.199  1.00 44.05  ? 189 HIS L N   1 
ATOM   6264 C CA  . HIS D 4 195 ? -50.742 18.264  19.913  1.00 45.08  ? 189 HIS L CA  1 
ATOM   6265 C C   . HIS D 4 195 ? -51.168 19.654  19.463  1.00 46.65  ? 189 HIS L C   1 
ATOM   6266 O O   . HIS D 4 195 ? -51.743 19.835  18.386  1.00 40.57  ? 189 HIS L O   1 
ATOM   6267 C CB  . HIS D 4 195 ? -49.237 18.077  19.688  1.00 42.87  ? 189 HIS L CB  1 
ATOM   6268 C CG  . HIS D 4 195 ? -48.760 16.678  19.926  1.00 41.00  ? 189 HIS L CG  1 
ATOM   6269 N ND1 . HIS D 4 195 ? -48.779 15.710  18.945  1.00 37.51  ? 189 HIS L ND1 1 
ATOM   6270 C CD2 . HIS D 4 195 ? -48.257 16.082  21.032  1.00 36.45  ? 189 HIS L CD2 1 
ATOM   6271 C CE1 . HIS D 4 195 ? -48.305 14.579  19.436  1.00 39.30  ? 189 HIS L CE1 1 
ATOM   6272 N NE2 . HIS D 4 195 ? -47.981 14.777  20.701  1.00 40.71  ? 189 HIS L NE2 1 
ATOM   6273 N N   . LYS D 4 196 ? -50.877 20.642  20.307  1.00 43.54  ? 190 LYS L N   1 
ATOM   6274 C CA  . LYS D 4 196 ? -51.303 22.017  20.085  1.00 37.28  ? 190 LYS L CA  1 
ATOM   6275 C C   . LYS D 4 196 ? -50.162 22.943  19.690  1.00 42.94  ? 190 LYS L C   1 
ATOM   6276 O O   . LYS D 4 196 ? -50.262 23.649  18.682  1.00 46.18  ? 190 LYS L O   1 
ATOM   6277 C CB  . LYS D 4 196 ? -51.994 22.554  21.348  1.00 34.42  ? 190 LYS L CB  1 
ATOM   6278 C CG  . LYS D 4 196 ? -52.606 23.937  21.193  1.00 51.81  ? 190 LYS L CG  1 
ATOM   6279 C CD  . LYS D 4 196 ? -53.256 24.390  22.491  1.00 53.64  ? 190 LYS L CD  1 
ATOM   6280 C CE  . LYS D 4 196 ? -54.344 23.421  22.929  1.00 59.23  ? 190 LYS L CE  1 
ATOM   6281 N NZ  . LYS D 4 196 ? -54.115 22.914  24.311  1.00 50.14  ? 190 LYS L NZ  1 
ATOM   6282 N N   . VAL D 4 197 ? -49.073 22.957  20.454  1.00 39.53  ? 191 VAL L N   1 
ATOM   6283 C CA  . VAL D 4 197 ? -47.996 23.926  20.280  1.00 34.59  ? 191 VAL L CA  1 
ATOM   6284 C C   . VAL D 4 197 ? -46.884 23.302  19.448  1.00 36.04  ? 191 VAL L C   1 
ATOM   6285 O O   . VAL D 4 197 ? -46.393 22.212  19.767  1.00 37.52  ? 191 VAL L O   1 
ATOM   6286 C CB  . VAL D 4 197 ? -47.459 24.408  21.639  1.00 34.10  ? 191 VAL L CB  1 
ATOM   6287 C CG1 . VAL D 4 197 ? -46.352 25.433  21.439  1.00 29.64  ? 191 VAL L CG1 1 
ATOM   6288 C CG2 . VAL D 4 197 ? -48.587 24.987  22.478  1.00 37.31  ? 191 VAL L CG2 1 
ATOM   6289 N N   . TYR D 4 198 ? -46.484 23.997  18.385  1.00 41.39  ? 192 TYR L N   1 
ATOM   6290 C CA  . TYR D 4 198 ? -45.377 23.588  17.525  1.00 30.72  ? 192 TYR L CA  1 
ATOM   6291 C C   . TYR D 4 198 ? -44.361 24.721  17.502  1.00 35.91  ? 192 TYR L C   1 
ATOM   6292 O O   . TYR D 4 198 ? -44.645 25.804  16.980  1.00 38.80  ? 192 TYR L O   1 
ATOM   6293 C CB  . TYR D 4 198 ? -45.869 23.253  16.118  1.00 26.89  ? 192 TYR L CB  1 
ATOM   6294 C CG  . TYR D 4 198 ? -46.731 22.015  16.071  1.00 35.67  ? 192 TYR L CG  1 
ATOM   6295 C CD1 . TYR D 4 198 ? -48.077 22.068  16.411  1.00 39.99  ? 192 TYR L CD1 1 
ATOM   6296 C CD2 . TYR D 4 198 ? -46.196 20.790  15.698  1.00 30.35  ? 192 TYR L CD2 1 
ATOM   6297 C CE1 . TYR D 4 198 ? -48.865 20.936  16.377  1.00 33.04  ? 192 TYR L CE1 1 
ATOM   6298 C CE2 . TYR D 4 198 ? -46.977 19.654  15.660  1.00 36.78  ? 192 TYR L CE2 1 
ATOM   6299 C CZ  . TYR D 4 198 ? -48.309 19.733  16.001  1.00 34.66  ? 192 TYR L CZ  1 
ATOM   6300 O OH  . TYR D 4 198 ? -49.088 18.603  15.965  1.00 44.45  ? 192 TYR L OH  1 
ATOM   6301 N N   . ALA D 4 199 ? -43.179 24.472  18.060  1.00 34.12  ? 193 ALA L N   1 
ATOM   6302 C CA  . ALA D 4 199 ? -42.178 25.506  18.271  1.00 29.43  ? 193 ALA L CA  1 
ATOM   6303 C C   . ALA D 4 199 ? -40.888 25.165  17.539  1.00 30.34  ? 193 ALA L C   1 
ATOM   6304 O O   . ALA D 4 199 ? -40.469 24.004  17.501  1.00 35.92  ? 193 ALA L O   1 
ATOM   6305 C CB  . ALA D 4 199 ? -41.890 25.695  19.763  1.00 25.59  ? 193 ALA L CB  1 
ATOM   6306 N N   . CYS D 4 200 ? -40.266 26.188  16.962  1.00 35.94  ? 194 CYS L N   1 
ATOM   6307 C CA  . CYS D 4 200 ? -38.958 26.083  16.329  1.00 30.29  ? 194 CYS L CA  1 
ATOM   6308 C C   . CYS D 4 200 ? -37.971 26.919  17.132  1.00 32.63  ? 194 CYS L C   1 
ATOM   6309 O O   . CYS D 4 200 ? -38.120 28.142  17.222  1.00 36.44  ? 194 CYS L O   1 
ATOM   6310 C CB  . CYS D 4 200 ? -39.012 26.558  14.878  1.00 29.00  ? 194 CYS L CB  1 
ATOM   6311 S SG  . CYS D 4 200 ? -37.400 26.709  14.082  1.00 64.45  ? 194 CYS L SG  1 
ATOM   6312 N N   . GLU D 4 201 ? -36.966 26.263  17.705  1.00 24.61  ? 195 GLU L N   1 
ATOM   6313 C CA  . GLU D 4 201 ? -35.993 26.908  18.578  1.00 29.19  ? 195 GLU L CA  1 
ATOM   6314 C C   . GLU D 4 201 ? -34.673 27.038  17.831  1.00 34.64  ? 195 GLU L C   1 
ATOM   6315 O O   . GLU D 4 201 ? -34.102 26.034  17.394  1.00 39.62  ? 195 GLU L O   1 
ATOM   6316 C CB  . GLU D 4 201 ? -35.815 26.108  19.868  1.00 37.38  ? 195 GLU L CB  1 
ATOM   6317 C CG  . GLU D 4 201 ? -35.435 26.944  21.076  1.00 45.92  ? 195 GLU L CG  1 
ATOM   6318 C CD  . GLU D 4 201 ? -35.498 26.154  22.369  1.00 58.82  ? 195 GLU L CD  1 
ATOM   6319 O OE1 . GLU D 4 201 ? -36.426 25.330  22.521  1.00 50.73  ? 195 GLU L OE1 1 
ATOM   6320 O OE2 . GLU D 4 201 ? -34.617 26.354  23.232  1.00 61.62  ? 195 GLU L OE2 1 
ATOM   6321 N N   . VAL D 4 202 ? -34.190 28.271  17.694  1.00 30.57  ? 196 VAL L N   1 
ATOM   6322 C CA  . VAL D 4 202 ? -33.013 28.581  16.891  1.00 29.46  ? 196 VAL L CA  1 
ATOM   6323 C C   . VAL D 4 202 ? -31.932 29.145  17.801  1.00 32.62  ? 196 VAL L C   1 
ATOM   6324 O O   . VAL D 4 202 ? -32.178 30.099  18.548  1.00 34.41  ? 196 VAL L O   1 
ATOM   6325 C CB  . VAL D 4 202 ? -33.345 29.574  15.762  1.00 30.97  ? 196 VAL L CB  1 
ATOM   6326 C CG1 . VAL D 4 202 ? -32.075 30.018  15.056  1.00 25.55  ? 196 VAL L CG1 1 
ATOM   6327 C CG2 . VAL D 4 202 ? -34.319 28.948  14.777  1.00 31.02  ? 196 VAL L CG2 1 
ATOM   6328 N N   . THR D 4 203 ? -30.739 28.559  17.730  1.00 42.56  ? 197 THR L N   1 
ATOM   6329 C CA  . THR D 4 203 ? -29.572 29.032  18.461  1.00 26.93  ? 197 THR L CA  1 
ATOM   6330 C C   . THR D 4 203 ? -28.476 29.382  17.465  1.00 27.06  ? 197 THR L C   1 
ATOM   6331 O O   . THR D 4 203 ? -28.123 28.560  16.612  1.00 35.17  ? 197 THR L O   1 
ATOM   6332 C CB  . THR D 4 203 ? -29.074 27.977  19.454  1.00 29.72  ? 197 THR L CB  1 
ATOM   6333 O OG1 . THR D 4 203 ? -30.090 27.722  20.433  1.00 36.89  ? 197 THR L OG1 1 
ATOM   6334 C CG2 . THR D 4 203 ? -27.811 28.453  20.154  1.00 30.75  ? 197 THR L CG2 1 
ATOM   6335 N N   . HIS D 4 204 ? -27.940 30.596  17.573  1.00 27.37  ? 198 HIS L N   1 
ATOM   6336 C CA  . HIS D 4 204 ? -26.933 31.072  16.637  1.00 28.89  ? 198 HIS L CA  1 
ATOM   6337 C C   . HIS D 4 204 ? -25.968 31.991  17.373  1.00 32.59  ? 198 HIS L C   1 
ATOM   6338 O O   . HIS D 4 204 ? -26.286 32.540  18.430  1.00 40.96  ? 198 HIS L O   1 
ATOM   6339 C CB  . HIS D 4 204 ? -27.577 31.795  15.447  1.00 26.53  ? 198 HIS L CB  1 
ATOM   6340 C CG  . HIS D 4 204 ? -26.622 32.111  14.337  1.00 28.24  ? 198 HIS L CG  1 
ATOM   6341 N ND1 . HIS D 4 204 ? -26.037 33.349  14.189  1.00 32.96  ? 198 HIS L ND1 1 
ATOM   6342 C CD2 . HIS D 4 204 ? -26.155 31.350  13.320  1.00 36.39  ? 198 HIS L CD2 1 
ATOM   6343 C CE1 . HIS D 4 204 ? -25.247 33.338  13.130  1.00 28.69  ? 198 HIS L CE1 1 
ATOM   6344 N NE2 . HIS D 4 204 ? -25.301 32.136  12.584  1.00 38.76  ? 198 HIS L NE2 1 
ATOM   6345 N N   . GLN D 4 205 ? -24.773 32.147  16.795  1.00 39.63  ? 199 GLN L N   1 
ATOM   6346 C CA  . GLN D 4 205 ? -23.752 32.992  17.409  1.00 41.49  ? 199 GLN L CA  1 
ATOM   6347 C C   . GLN D 4 205 ? -24.195 34.448  17.483  1.00 48.15  ? 199 GLN L C   1 
ATOM   6348 O O   . GLN D 4 205 ? -23.839 35.157  18.432  1.00 46.02  ? 199 GLN L O   1 
ATOM   6349 C CB  . GLN D 4 205 ? -22.439 32.873  16.633  1.00 35.36  ? 199 GLN L CB  1 
ATOM   6350 C CG  . GLN D 4 205 ? -21.290 33.681  17.217  1.00 46.89  ? 199 GLN L CG  1 
ATOM   6351 C CD  . GLN D 4 205 ? -20.020 33.570  16.397  1.00 58.49  ? 199 GLN L CD  1 
ATOM   6352 O OE1 . GLN D 4 205 ? -19.933 32.762  15.472  1.00 55.24  ? 199 GLN L OE1 1 
ATOM   6353 N NE2 . GLN D 4 205 ? -19.025 34.385  16.731  1.00 56.52  ? 199 GLN L NE2 1 
ATOM   6354 N N   . GLY D 4 206 ? -24.975 34.907  16.507  1.00 34.01  ? 200 GLY L N   1 
ATOM   6355 C CA  . GLY D 4 206 ? -25.449 36.273  16.456  1.00 35.79  ? 200 GLY L CA  1 
ATOM   6356 C C   . GLY D 4 206 ? -26.673 36.569  17.288  1.00 45.98  ? 200 GLY L C   1 
ATOM   6357 O O   . GLY D 4 206 ? -27.218 37.673  17.202  1.00 41.51  ? 200 GLY L O   1 
ATOM   6358 N N   . LEU D 4 207 ? -27.131 35.613  18.091  1.00 47.08  ? 201 LEU L N   1 
ATOM   6359 C CA  . LEU D 4 207 ? -28.295 35.783  18.949  1.00 39.59  ? 201 LEU L CA  1 
ATOM   6360 C C   . LEU D 4 207 ? -27.857 35.748  20.407  1.00 47.94  ? 201 LEU L C   1 
ATOM   6361 O O   . LEU D 4 207 ? -27.090 34.866  20.807  1.00 54.47  ? 201 LEU L O   1 
ATOM   6362 C CB  . LEU D 4 207 ? -29.333 34.692  18.680  1.00 36.30  ? 201 LEU L CB  1 
ATOM   6363 C CG  . LEU D 4 207 ? -29.917 34.639  17.268  1.00 36.00  ? 201 LEU L CG  1 
ATOM   6364 C CD1 . LEU D 4 207 ? -30.714 33.361  17.072  1.00 29.41  ? 201 LEU L CD1 1 
ATOM   6365 C CD2 . LEU D 4 207 ? -30.785 35.858  17.002  1.00 29.84  ? 201 LEU L CD2 1 
ATOM   6366 N N   . SER D 4 208 ? -28.339 36.714  21.193  1.00 53.16  ? 202 SER L N   1 
ATOM   6367 C CA  . SER D 4 208 ? -28.017 36.737  22.617  1.00 47.72  ? 202 SER L CA  1 
ATOM   6368 C C   . SER D 4 208 ? -28.572 35.508  23.326  1.00 55.43  ? 202 SER L C   1 
ATOM   6369 O O   . SER D 4 208 ? -27.889 34.897  24.156  1.00 48.06  ? 202 SER L O   1 
ATOM   6370 C CB  . SER D 4 208 ? -28.561 38.014  23.258  1.00 40.82  ? 202 SER L CB  1 
ATOM   6371 O OG  . SER D 4 208 ? -28.054 39.169  22.613  1.00 45.34  ? 202 SER L OG  1 
ATOM   6372 N N   . SER D 4 209 ? -29.803 35.134  23.010  1.00 58.58  ? 203 SER L N   1 
ATOM   6373 C CA  . SER D 4 209 ? -30.470 33.972  23.571  1.00 55.69  ? 203 SER L CA  1 
ATOM   6374 C C   . SER D 4 209 ? -31.184 33.250  22.440  1.00 54.99  ? 203 SER L C   1 
ATOM   6375 O O   . SER D 4 209 ? -31.425 33.838  21.380  1.00 46.87  ? 203 SER L O   1 
ATOM   6376 C CB  . SER D 4 209 ? -31.467 34.370  24.669  1.00 47.22  ? 203 SER L CB  1 
ATOM   6377 O OG  . SER D 4 209 ? -32.536 35.131  24.136  1.00 63.08  ? 203 SER L OG  1 
ATOM   6378 N N   . PRO D 4 210 ? -31.513 31.970  22.623  1.00 50.85  ? 204 PRO L N   1 
ATOM   6379 C CA  . PRO D 4 210 ? -32.227 31.242  21.567  1.00 47.65  ? 204 PRO L CA  1 
ATOM   6380 C C   . PRO D 4 210 ? -33.551 31.908  21.219  1.00 48.11  ? 204 PRO L C   1 
ATOM   6381 O O   . PRO D 4 210 ? -34.271 32.401  22.090  1.00 51.47  ? 204 PRO L O   1 
ATOM   6382 C CB  . PRO D 4 210 ? -32.438 29.852  22.176  1.00 41.57  ? 204 PRO L CB  1 
ATOM   6383 C CG  . PRO D 4 210 ? -31.330 29.707  23.157  1.00 43.50  ? 204 PRO L CG  1 
ATOM   6384 C CD  . PRO D 4 210 ? -31.109 31.079  23.726  1.00 37.45  ? 204 PRO L CD  1 
ATOM   6385 N N   . VAL D 4 211 ? -33.864 31.917  19.926  1.00 37.68  ? 205 VAL L N   1 
ATOM   6386 C CA  . VAL D 4 211 ? -35.089 32.514  19.405  1.00 34.25  ? 205 VAL L CA  1 
ATOM   6387 C C   . VAL D 4 211 ? -36.080 31.397  19.113  1.00 36.84  ? 205 VAL L C   1 
ATOM   6388 O O   . VAL D 4 211 ? -35.726 30.391  18.486  1.00 38.03  ? 205 VAL L O   1 
ATOM   6389 C CB  . VAL D 4 211 ? -34.810 33.349  18.144  1.00 29.07  ? 205 VAL L CB  1 
ATOM   6390 C CG1 . VAL D 4 211 ? -36.112 33.797  17.497  1.00 22.27  ? 205 VAL L CG1 1 
ATOM   6391 C CG2 . VAL D 4 211 ? -33.943 34.549  18.487  1.00 29.98  ? 205 VAL L CG2 1 
ATOM   6392 N N   . THR D 4 212 ? -37.318 31.567  19.571  1.00 35.79  ? 206 THR L N   1 
ATOM   6393 C CA  . THR D 4 212 ? -38.361 30.563  19.404  1.00 30.19  ? 206 THR L CA  1 
ATOM   6394 C C   . THR D 4 212 ? -39.550 31.179  18.680  1.00 33.29  ? 206 THR L C   1 
ATOM   6395 O O   . THR D 4 212 ? -40.122 32.170  19.147  1.00 39.36  ? 206 THR L O   1 
ATOM   6396 C CB  . THR D 4 212 ? -38.796 29.994  20.757  1.00 33.97  ? 206 THR L CB  1 
ATOM   6397 O OG1 . THR D 4 212 ? -37.657 29.450  21.435  1.00 38.49  ? 206 THR L OG1 1 
ATOM   6398 C CG2 . THR D 4 212 ? -39.833 28.899  20.562  1.00 31.39  ? 206 THR L CG2 1 
ATOM   6399 N N   . LYS D 4 213 ? -39.915 30.590  17.546  1.00 33.53  ? 207 LYS L N   1 
ATOM   6400 C CA  . LYS D 4 213 ? -41.137 30.919  16.825  1.00 34.19  ? 207 LYS L CA  1 
ATOM   6401 C C   . LYS D 4 213 ? -42.088 29.736  16.930  1.00 36.80  ? 207 LYS L C   1 
ATOM   6402 O O   . LYS D 4 213 ? -41.698 28.599  16.644  1.00 32.25  ? 207 LYS L O   1 
ATOM   6403 C CB  . LYS D 4 213 ? -40.844 31.240  15.357  1.00 35.68  ? 207 LYS L CB  1 
ATOM   6404 C CG  . LYS D 4 213 ? -40.084 32.537  15.130  1.00 39.70  ? 207 LYS L CG  1 
ATOM   6405 C CD  . LYS D 4 213 ? -40.979 33.748  15.338  1.00 47.36  ? 207 LYS L CD  1 
ATOM   6406 C CE  . LYS D 4 213 ? -40.259 35.034  14.966  1.00 53.61  ? 207 LYS L CE  1 
ATOM   6407 N NZ  . LYS D 4 213 ? -41.165 36.215  15.021  1.00 55.07  ? 207 LYS L NZ  1 
ATOM   6408 N N   . SER D 4 214 ? -43.327 30.001  17.340  1.00 37.80  ? 208 SER L N   1 
ATOM   6409 C CA  . SER D 4 214 ? -44.279 28.936  17.620  1.00 39.79  ? 208 SER L CA  1 
ATOM   6410 C C   . SER D 4 214 ? -45.683 29.364  17.219  1.00 42.65  ? 208 SER L C   1 
ATOM   6411 O O   . SER D 4 214 ? -45.977 30.551  17.061  1.00 46.13  ? 208 SER L O   1 
ATOM   6412 C CB  . SER D 4 214 ? -44.262 28.540  19.103  1.00 37.83  ? 208 SER L CB  1 
ATOM   6413 O OG  . SER D 4 214 ? -44.532 29.657  19.931  1.00 39.18  ? 208 SER L OG  1 
ATOM   6414 N N   . PHE D 4 215 ? -46.549 28.365  17.059  1.00 41.11  ? 209 PHE L N   1 
ATOM   6415 C CA  . PHE D 4 215 ? -47.952 28.588  16.750  1.00 35.49  ? 209 PHE L CA  1 
ATOM   6416 C C   . PHE D 4 215 ? -48.775 27.491  17.409  1.00 43.49  ? 209 PHE L C   1 
ATOM   6417 O O   . PHE D 4 215 ? -48.250 26.462  17.841  1.00 33.84  ? 209 PHE L O   1 
ATOM   6418 C CB  . PHE D 4 215 ? -48.204 28.629  15.236  1.00 35.40  ? 209 PHE L CB  1 
ATOM   6419 C CG  . PHE D 4 215 ? -47.984 27.310  14.540  1.00 36.68  ? 209 PHE L CG  1 
ATOM   6420 C CD1 . PHE D 4 215 ? -49.021 26.399  14.398  1.00 32.53  ? 209 PHE L CD1 1 
ATOM   6421 C CD2 . PHE D 4 215 ? -46.745 26.989  14.011  1.00 39.94  ? 209 PHE L CD2 1 
ATOM   6422 C CE1 . PHE D 4 215 ? -48.822 25.190  13.757  1.00 35.93  ? 209 PHE L CE1 1 
ATOM   6423 C CE2 . PHE D 4 215 ? -46.540 25.781  13.366  1.00 32.59  ? 209 PHE L CE2 1 
ATOM   6424 C CZ  . PHE D 4 215 ? -47.581 24.881  13.239  1.00 35.81  ? 209 PHE L CZ  1 
ATOM   6425 N N   . ASN D 4 216 ? -50.081 27.725  17.481  1.00 51.28  ? 210 ASN L N   1 
ATOM   6426 C CA  . ASN D 4 216 ? -51.034 26.752  17.992  1.00 43.64  ? 210 ASN L CA  1 
ATOM   6427 C C   . ASN D 4 216 ? -51.861 26.204  16.840  1.00 45.52  ? 210 ASN L C   1 
ATOM   6428 O O   . ASN D 4 216 ? -52.253 26.949  15.936  1.00 47.47  ? 210 ASN L O   1 
ATOM   6429 C CB  . ASN D 4 216 ? -51.950 27.374  19.047  1.00 56.04  ? 210 ASN L CB  1 
ATOM   6430 C CG  . ASN D 4 216 ? -51.180 27.962  20.209  1.00 61.52  ? 210 ASN L CG  1 
ATOM   6431 O OD1 . ASN D 4 216 ? -50.029 27.600  20.447  1.00 66.81  ? 210 ASN L OD1 1 
ATOM   6432 N ND2 . ASN D 4 216 ? -51.813 28.871  20.943  1.00 55.99  ? 210 ASN L ND2 1 
ATOM   6433 N N   . ARG D 4 217 ? -52.123 24.900  16.877  1.00 42.05  ? 211 ARG L N   1 
ATOM   6434 C CA  . ARG D 4 217 ? -52.854 24.247  15.799  1.00 48.99  ? 211 ARG L CA  1 
ATOM   6435 C C   . ARG D 4 217 ? -54.267 24.805  15.694  1.00 58.64  ? 211 ARG L C   1 
ATOM   6436 O O   . ARG D 4 217 ? -55.056 24.709  16.639  1.00 65.97  ? 211 ARG L O   1 
ATOM   6437 C CB  . ARG D 4 217 ? -52.890 22.737  16.032  1.00 52.03  ? 211 ARG L CB  1 
ATOM   6438 C CG  . ARG D 4 217 ? -53.831 21.986  15.105  1.00 46.99  ? 211 ARG L CG  1 
ATOM   6439 C CD  . ARG D 4 217 ? -53.832 20.498  15.412  1.00 49.65  ? 211 ARG L CD  1 
ATOM   6440 N NE  . ARG D 4 217 ? -53.985 20.236  16.838  1.00 53.68  ? 211 ARG L NE  1 
ATOM   6441 C CZ  . ARG D 4 217 ? -55.149 20.188  17.473  1.00 50.80  ? 211 ARG L CZ  1 
ATOM   6442 N NH1 . ARG D 4 217 ? -56.292 20.384  16.837  1.00 60.18  ? 211 ARG L NH1 1 
ATOM   6443 N NH2 . ARG D 4 217 ? -55.165 19.940  18.780  1.00 52.69  ? 211 ARG L NH2 1 
ATOM   6444 N N   . GLY D 4 218 ? -54.581 25.387  14.539  1.00 65.12  ? 212 GLY L N   1 
ATOM   6445 C CA  . GLY D 4 218 ? -55.900 25.942  14.300  1.00 69.45  ? 212 GLY L CA  1 
ATOM   6446 C C   . GLY D 4 218 ? -56.259 27.120  15.177  1.00 67.47  ? 212 GLY L C   1 
ATOM   6447 O O   . GLY D 4 218 ? -57.437 27.315  15.488  1.00 83.14  ? 212 GLY L O   1 
ATOM   6448 N N   . GLU D 4 219 ? -55.273 27.914  15.586  1.00 73.71  ? 213 GLU L N   1 
ATOM   6449 C CA  . GLU D 4 219 ? -55.528 29.070  16.440  1.00 67.19  ? 213 GLU L CA  1 
ATOM   6450 C C   . GLU D 4 219 ? -54.707 30.272  15.988  1.00 68.27  ? 213 GLU L C   1 
ATOM   6451 O O   . GLU D 4 219 ? -54.754 30.667  14.823  1.00 76.29  ? 213 GLU L O   1 
ATOM   6452 C CB  . GLU D 4 219 ? -55.216 28.747  17.905  1.00 64.09  ? 213 GLU L CB  1 
ATOM   6453 C CG  . GLU D 4 219 ? -55.839 27.449  18.400  1.00 79.71  ? 213 GLU L CG  1 
ATOM   6454 C CD  . GLU D 4 219 ? -55.956 27.385  19.910  1.00 85.39  ? 213 GLU L CD  1 
ATOM   6455 O OE1 . GLU D 4 219 ? -55.687 28.405  20.576  1.00 82.07  ? 213 GLU L OE1 1 
ATOM   6456 O OE2 . GLU D 4 219 ? -56.321 26.309  20.431  1.00 80.86  ? 213 GLU L OE2 1 
ATOM   6457 N N   . GLU E 5 1   ? -8.122  -12.789 -32.758 1.00 64.96  ? 1   GLU G N   1 
ATOM   6458 C CA  . GLU E 5 1   ? -7.499  -14.034 -33.193 1.00 58.02  ? 1   GLU G CA  1 
ATOM   6459 C C   . GLU E 5 1   ? -7.685  -14.265 -34.687 1.00 54.30  ? 1   GLU G C   1 
ATOM   6460 O O   . GLU E 5 1   ? -8.550  -13.658 -35.319 1.00 64.61  ? 1   GLU G O   1 
ATOM   6461 C CB  . GLU E 5 1   ? -8.069  -15.224 -32.419 1.00 58.90  ? 1   GLU G CB  1 
ATOM   6462 C CG  . GLU E 5 1   ? -7.716  -15.246 -30.943 1.00 72.86  ? 1   GLU G CG  1 
ATOM   6463 C CD  . GLU E 5 1   ? -8.042  -16.579 -30.296 1.00 80.13  ? 1   GLU G CD  1 
ATOM   6464 O OE1 . GLU E 5 1   ? -8.303  -17.551 -31.036 1.00 64.50  ? 1   GLU G OE1 1 
ATOM   6465 O OE2 . GLU E 5 1   ? -8.039  -16.656 -29.049 1.00 81.61  ? 1   GLU G OE2 1 
ATOM   6466 N N   . ILE E 5 2   ? -6.868  -15.155 -35.242 1.00 47.59  ? 2   ILE G N   1 
ATOM   6467 C CA  . ILE E 5 2   ? -6.941  -15.540 -36.646 1.00 45.32  ? 2   ILE G CA  1 
ATOM   6468 C C   . ILE E 5 2   ? -7.293  -17.018 -36.708 1.00 46.24  ? 2   ILE G C   1 
ATOM   6469 O O   . ILE E 5 2   ? -6.639  -17.844 -36.061 1.00 40.71  ? 2   ILE G O   1 
ATOM   6470 C CB  . ILE E 5 2   ? -5.622  -15.253 -37.386 1.00 37.69  ? 2   ILE G CB  1 
ATOM   6471 C CG1 . ILE E 5 2   ? -5.369  -13.745 -37.450 1.00 43.27  ? 2   ILE G CG1 1 
ATOM   6472 C CG2 . ILE E 5 2   ? -5.648  -15.854 -38.784 1.00 33.70  ? 2   ILE G CG2 1 
ATOM   6473 C CD1 . ILE E 5 2   ? -4.216  -13.354 -38.346 1.00 40.55  ? 2   ILE G CD1 1 
ATOM   6474 N N   . VAL E 5 3   ? -8.324  -17.347 -37.481 1.00 33.94  ? 3   VAL G N   1 
ATOM   6475 C CA  . VAL E 5 3   ? -8.828  -18.711 -37.589 1.00 42.29  ? 3   VAL G CA  1 
ATOM   6476 C C   . VAL E 5 3   ? -8.270  -19.345 -38.855 1.00 39.63  ? 3   VAL G C   1 
ATOM   6477 O O   . VAL E 5 3   ? -8.370  -18.768 -39.945 1.00 49.31  ? 3   VAL G O   1 
ATOM   6478 C CB  . VAL E 5 3   ? -10.366 -18.739 -37.593 1.00 44.90  ? 3   VAL G CB  1 
ATOM   6479 C CG1 . VAL E 5 3   ? -10.870 -20.163 -37.767 1.00 30.72  ? 3   VAL G CG1 1 
ATOM   6480 C CG2 . VAL E 5 3   ? -10.911 -18.128 -36.311 1.00 38.58  ? 3   VAL G CG2 1 
ATOM   6481 N N   . LEU E 5 4   ? -7.684  -20.530 -38.711 1.00 31.11  ? 4   LEU G N   1 
ATOM   6482 C CA  . LEU E 5 4   ? -7.170  -21.298 -39.836 1.00 38.30  ? 4   LEU G CA  1 
ATOM   6483 C C   . LEU E 5 4   ? -8.143  -22.422 -40.164 1.00 42.55  ? 4   LEU G C   1 
ATOM   6484 O O   . LEU E 5 4   ? -8.564  -23.166 -39.272 1.00 58.29  ? 4   LEU G O   1 
ATOM   6485 C CB  . LEU E 5 4   ? -5.786  -21.870 -39.525 1.00 51.93  ? 4   LEU G CB  1 
ATOM   6486 C CG  . LEU E 5 4   ? -4.600  -20.912 -39.630 1.00 47.23  ? 4   LEU G CG  1 
ATOM   6487 C CD1 . LEU E 5 4   ? -3.349  -21.553 -39.060 1.00 39.24  ? 4   LEU G CD1 1 
ATOM   6488 C CD2 . LEU E 5 4   ? -4.377  -20.510 -41.074 1.00 52.66  ? 4   LEU G CD2 1 
ATOM   6489 N N   . THR E 5 5   ? -8.498  -22.540 -41.440 1.00 43.41  ? 5   THR G N   1 
ATOM   6490 C CA  . THR E 5 5   ? -9.426  -23.557 -41.913 1.00 38.52  ? 5   THR G CA  1 
ATOM   6491 C C   . THR E 5 5   ? -8.709  -24.464 -42.900 1.00 39.42  ? 5   THR G C   1 
ATOM   6492 O O   . THR E 5 5   ? -8.110  -23.984 -43.867 1.00 50.24  ? 5   THR G O   1 
ATOM   6493 C CB  . THR E 5 5   ? -10.653 -22.920 -42.572 1.00 44.88  ? 5   THR G CB  1 
ATOM   6494 O OG1 . THR E 5 5   ? -11.280 -22.022 -41.648 1.00 41.57  ? 5   THR G OG1 1 
ATOM   6495 C CG2 . THR E 5 5   ? -11.648 -23.992 -42.986 1.00 53.66  ? 5   THR G CG2 1 
ATOM   6496 N N   . GLN E 5 6   ? -8.772  -25.770 -42.657 1.00 34.72  ? 6   GLN G N   1 
ATOM   6497 C CA  . GLN E 5 6   ? -8.107  -26.756 -43.494 1.00 42.64  ? 6   GLN G CA  1 
ATOM   6498 C C   . GLN E 5 6   ? -9.138  -27.579 -44.252 1.00 45.24  ? 6   GLN G C   1 
ATOM   6499 O O   . GLN E 5 6   ? -10.185 -27.941 -43.705 1.00 61.41  ? 6   GLN G O   1 
ATOM   6500 C CB  . GLN E 5 6   ? -7.220  -27.684 -42.659 1.00 43.07  ? 6   GLN G CB  1 
ATOM   6501 C CG  . GLN E 5 6   ? -6.151  -26.966 -41.857 1.00 37.75  ? 6   GLN G CG  1 
ATOM   6502 C CD  . GLN E 5 6   ? -5.132  -27.918 -41.261 1.00 43.53  ? 6   GLN G CD  1 
ATOM   6503 O OE1 . GLN E 5 6   ? -4.729  -27.772 -40.107 1.00 43.39  ? 6   GLN G OE1 1 
ATOM   6504 N NE2 . GLN E 5 6   ? -4.705  -28.897 -42.050 1.00 34.69  ? 6   GLN G NE2 1 
ATOM   6505 N N   . SER E 5 7   ? -8.835  -27.869 -45.517 1.00 50.00  ? 7   SER G N   1 
ATOM   6506 C CA  . SER E 5 7   ? -9.678  -28.692 -46.364 1.00 50.16  ? 7   SER G CA  1 
ATOM   6507 C C   . SER E 5 7   ? -8.790  -29.604 -47.199 1.00 55.57  ? 7   SER G C   1 
ATOM   6508 O O   . SER E 5 7   ? -7.741  -29.165 -47.694 1.00 53.64  ? 7   SER G O   1 
ATOM   6509 C CB  . SER E 5 7   ? -10.567 -27.843 -47.282 1.00 49.16  ? 7   SER G CB  1 
ATOM   6510 O OG  . SER E 5 7   ? -9.795  -26.916 -48.025 1.00 57.90  ? 7   SER G OG  1 
ATOM   6511 N N   . PRO E 5 8   ? -9.175  -30.874 -47.372 1.00 51.04  ? 8   PRO G N   1 
ATOM   6512 C CA  . PRO E 5 8   ? -10.377 -31.530 -46.837 1.00 60.40  ? 8   PRO G CA  1 
ATOM   6513 C C   . PRO E 5 8   ? -10.238 -31.879 -45.359 1.00 63.28  ? 8   PRO G C   1 
ATOM   6514 O O   . PRO E 5 8   ? -9.133  -31.889 -44.822 1.00 45.58  ? 8   PRO G O   1 
ATOM   6515 C CB  . PRO E 5 8   ? -10.490 -32.783 -47.712 1.00 55.96  ? 8   PRO G CB  1 
ATOM   6516 C CG  . PRO E 5 8   ? -9.061  -33.133 -48.013 1.00 47.77  ? 8   PRO G CG  1 
ATOM   6517 C CD  . PRO E 5 8   ? -8.360  -31.804 -48.176 1.00 43.19  ? 8   PRO G CD  1 
ATOM   6518 N N   . GLY E 5 9   ? -11.351 -32.152 -44.673 1.00 63.21  ? 9   GLY G N   1 
ATOM   6519 C CA  . GLY E 5 9   ? -11.265 -32.617 -43.300 1.00 42.05  ? 9   GLY G CA  1 
ATOM   6520 C C   . GLY E 5 9   ? -10.554 -33.949 -43.184 1.00 54.86  ? 9   GLY G C   1 
ATOM   6521 O O   . GLY E 5 9   ? -9.866  -34.208 -42.193 1.00 55.42  ? 9   GLY G O   1 
ATOM   6522 N N   . THR E 5 10  ? -10.709 -34.809 -44.187 1.00 54.85  ? 10  THR G N   1 
ATOM   6523 C CA  . THR E 5 10  ? -9.978  -36.064 -44.252 1.00 49.59  ? 10  THR G CA  1 
ATOM   6524 C C   . THR E 5 10  ? -9.707  -36.390 -45.714 1.00 52.34  ? 10  THR G C   1 
ATOM   6525 O O   . THR E 5 10  ? -10.360 -35.862 -46.618 1.00 55.13  ? 10  THR G O   1 
ATOM   6526 C CB  . THR E 5 10  ? -10.736 -37.207 -43.565 1.00 52.70  ? 10  THR G CB  1 
ATOM   6527 O OG1 . THR E 5 10  ? -10.020 -38.437 -43.744 1.00 63.71  ? 10  THR G OG1 1 
ATOM   6528 C CG2 . THR E 5 10  ? -12.135 -37.346 -44.140 1.00 41.09  ? 10  THR G CG2 1 
ATOM   6529 N N   . LEU E 5 11  ? -8.721  -37.255 -45.940 1.00 45.09  ? 11  LEU G N   1 
ATOM   6530 C CA  . LEU E 5 11  ? -8.289  -37.589 -47.290 1.00 43.01  ? 11  LEU G CA  1 
ATOM   6531 C C   . LEU E 5 11  ? -7.804  -39.030 -47.309 1.00 53.68  ? 11  LEU G C   1 
ATOM   6532 O O   . LEU E 5 11  ? -7.301  -39.543 -46.307 1.00 47.22  ? 11  LEU G O   1 
ATOM   6533 C CB  . LEU E 5 11  ? -7.187  -36.633 -47.780 1.00 58.90  ? 11  LEU G CB  1 
ATOM   6534 C CG  . LEU E 5 11  ? -6.505  -36.844 -49.141 1.00 56.22  ? 11  LEU G CG  1 
ATOM   6535 C CD1 . LEU E 5 11  ? -7.483  -36.695 -50.299 1.00 45.61  ? 11  LEU G CD1 1 
ATOM   6536 C CD2 . LEU E 5 11  ? -5.324  -35.890 -49.306 1.00 62.30  ? 11  LEU G CD2 1 
ATOM   6537 N N   . SER E 5 12  ? -7.965  -39.682 -48.460 1.00 57.07  ? 12  SER G N   1 
ATOM   6538 C CA  . SER E 5 12  ? -7.659  -41.103 -48.598 1.00 57.98  ? 12  SER G CA  1 
ATOM   6539 C C   . SER E 5 12  ? -7.093  -41.354 -49.986 1.00 62.93  ? 12  SER G C   1 
ATOM   6540 O O   . SER E 5 12  ? -7.808  -41.209 -50.982 1.00 64.24  ? 12  SER G O   1 
ATOM   6541 C CB  . SER E 5 12  ? -8.909  -41.958 -48.369 1.00 56.21  ? 12  SER G CB  1 
ATOM   6542 O OG  . SER E 5 12  ? -8.581  -43.339 -48.285 1.00 68.96  ? 12  SER G OG  1 
ATOM   6543 N N   . LEU E 5 13  ? -5.823  -41.755 -50.049 1.00 45.68  ? 13  LEU G N   1 
ATOM   6544 C CA  . LEU E 5 13  ? -5.134  -41.959 -51.316 1.00 54.59  ? 13  LEU G CA  1 
ATOM   6545 C C   . LEU E 5 13  ? -4.260  -43.206 -51.242 1.00 64.32  ? 13  LEU G C   1 
ATOM   6546 O O   . LEU E 5 13  ? -3.891  -43.669 -50.161 1.00 67.71  ? 13  LEU G O   1 
ATOM   6547 C CB  . LEU E 5 13  ? -4.269  -40.747 -51.687 1.00 49.62  ? 13  LEU G CB  1 
ATOM   6548 C CG  . LEU E 5 13  ? -4.916  -39.360 -51.660 1.00 55.29  ? 13  LEU G CG  1 
ATOM   6549 C CD1 . LEU E 5 13  ? -3.864  -38.287 -51.851 1.00 53.63  ? 13  LEU G CD1 1 
ATOM   6550 C CD2 . LEU E 5 13  ? -6.001  -39.231 -52.717 1.00 51.52  ? 13  LEU G CD2 1 
ATOM   6551 N N   . SER E 5 14  ? -3.926  -43.742 -52.418 1.00 60.51  ? 14  SER G N   1 
ATOM   6552 C CA  . SER E 5 14  ? -3.067  -44.913 -52.525 1.00 61.84  ? 14  SER G CA  1 
ATOM   6553 C C   . SER E 5 14  ? -1.595  -44.508 -52.500 1.00 62.17  ? 14  SER G C   1 
ATOM   6554 O O   . SER E 5 14  ? -1.260  -43.340 -52.711 1.00 62.07  ? 14  SER G O   1 
ATOM   6555 C CB  . SER E 5 14  ? -3.382  -45.681 -53.808 1.00 63.50  ? 14  SER G CB  1 
ATOM   6556 O OG  . SER E 5 14  ? -4.628  -46.349 -53.709 1.00 68.44  ? 14  SER G OG  1 
ATOM   6557 N N   . PRO E 5 15  ? -0.692  -45.449 -52.207 1.00 61.09  ? 15  PRO G N   1 
ATOM   6558 C CA  . PRO E 5 15  ? 0.740   -45.136 -52.283 1.00 65.85  ? 15  PRO G CA  1 
ATOM   6559 C C   . PRO E 5 15  ? 1.172   -44.800 -53.704 1.00 70.44  ? 15  PRO G C   1 
ATOM   6560 O O   . PRO E 5 15  ? 0.663   -45.354 -54.682 1.00 71.92  ? 15  PRO G O   1 
ATOM   6561 C CB  . PRO E 5 15  ? 1.414   -46.419 -51.782 1.00 59.41  ? 15  PRO G CB  1 
ATOM   6562 C CG  . PRO E 5 15  ? 0.391   -47.489 -51.969 1.00 57.24  ? 15  PRO G CG  1 
ATOM   6563 C CD  . PRO E 5 15  ? -0.924  -46.818 -51.716 1.00 62.71  ? 15  PRO G CD  1 
ATOM   6564 N N   . GLY E 5 16  ? 2.133   -43.883 -53.806 1.00 66.89  ? 16  GLY G N   1 
ATOM   6565 C CA  . GLY E 5 16  ? 2.656   -43.449 -55.084 1.00 62.59  ? 16  GLY G CA  1 
ATOM   6566 C C   . GLY E 5 16  ? 1.916   -42.300 -55.733 1.00 64.66  ? 16  GLY G C   1 
ATOM   6567 O O   . GLY E 5 16  ? 2.342   -41.834 -56.797 1.00 63.54  ? 16  GLY G O   1 
ATOM   6568 N N   . GLU E 5 17  ? 0.829   -41.825 -55.132 1.00 55.05  ? 17  GLU G N   1 
ATOM   6569 C CA  . GLU E 5 17  ? 0.038   -40.745 -55.695 1.00 57.00  ? 17  GLU G CA  1 
ATOM   6570 C C   . GLU E 5 17  ? 0.405   -39.428 -55.014 1.00 60.44  ? 17  GLU G C   1 
ATOM   6571 O O   . GLU E 5 17  ? 1.214   -39.384 -54.084 1.00 58.86  ? 17  GLU G O   1 
ATOM   6572 C CB  . GLU E 5 17  ? -1.452  -41.067 -55.563 1.00 60.88  ? 17  GLU G CB  1 
ATOM   6573 C CG  . GLU E 5 17  ? -1.753  -42.558 -55.686 1.00 71.78  ? 17  GLU G CG  1 
ATOM   6574 C CD  . GLU E 5 17  ? -3.155  -42.846 -56.185 1.00 87.06  ? 17  GLU G CD  1 
ATOM   6575 O OE1 . GLU E 5 17  ? -3.322  -43.059 -57.405 1.00 98.88  ? 17  GLU G OE1 1 
ATOM   6576 O OE2 . GLU E 5 17  ? -4.091  -42.857 -55.359 1.00 91.02  ? 17  GLU G OE2 1 
ATOM   6577 N N   . ARG E 5 18  ? -0.189  -38.337 -55.488 1.00 52.44  ? 18  ARG G N   1 
ATOM   6578 C CA  . ARG E 5 18  ? 0.137   -37.001 -55.005 1.00 54.90  ? 18  ARG G CA  1 
ATOM   6579 C C   . ARG E 5 18  ? -1.012  -36.461 -54.165 1.00 54.69  ? 18  ARG G C   1 
ATOM   6580 O O   . ARG E 5 18  ? -2.175  -36.534 -54.574 1.00 57.21  ? 18  ARG G O   1 
ATOM   6581 C CB  . ARG E 5 18  ? 0.439   -36.050 -56.167 1.00 57.35  ? 18  ARG G CB  1 
ATOM   6582 C CG  . ARG E 5 18  ? 1.183   -34.790 -55.742 1.00 48.75  ? 18  ARG G CG  1 
ATOM   6583 C CD  . ARG E 5 18  ? 1.222   -33.739 -56.844 1.00 54.95  ? 18  ARG G CD  1 
ATOM   6584 N NE  . ARG E 5 18  ? 2.441   -33.796 -57.643 1.00 67.78  ? 18  ARG G NE  1 
ATOM   6585 C CZ  . ARG E 5 18  ? 2.525   -34.339 -58.850 1.00 65.11  ? 18  ARG G CZ  1 
ATOM   6586 N NH1 . ARG E 5 18  ? 1.478   -34.906 -59.427 1.00 65.36  ? 18  ARG G NH1 1 
ATOM   6587 N NH2 . ARG E 5 18  ? 3.687   -34.309 -59.496 1.00 67.91  ? 18  ARG G NH2 1 
ATOM   6588 N N   . ALA E 5 19  ? -0.680  -35.919 -52.996 1.00 61.82  ? 19  ALA G N   1 
ATOM   6589 C CA  . ALA E 5 19  ? -1.656  -35.371 -52.064 1.00 54.15  ? 19  ALA G CA  1 
ATOM   6590 C C   . ALA E 5 19  ? -1.563  -33.852 -52.057 1.00 53.28  ? 19  ALA G C   1 
ATOM   6591 O O   . ALA E 5 19  ? -0.462  -33.293 -51.997 1.00 60.32  ? 19  ALA G O   1 
ATOM   6592 C CB  . ALA E 5 19  ? -1.434  -35.917 -50.652 1.00 46.27  ? 19  ALA G CB  1 
ATOM   6593 N N   . THR E 5 20  ? -2.716  -33.190 -52.119 1.00 42.63  ? 20  THR G N   1 
ATOM   6594 C CA  . THR E 5 20  ? -2.800  -31.736 -52.069 1.00 41.46  ? 20  THR G CA  1 
ATOM   6595 C C   . THR E 5 20  ? -3.662  -31.341 -50.879 1.00 46.91  ? 20  THR G C   1 
ATOM   6596 O O   . THR E 5 20  ? -4.850  -31.677 -50.832 1.00 60.87  ? 20  THR G O   1 
ATOM   6597 C CB  . THR E 5 20  ? -3.382  -31.168 -53.365 1.00 59.23  ? 20  THR G CB  1 
ATOM   6598 O OG1 . THR E 5 20  ? -2.458  -31.381 -54.440 1.00 69.00  ? 20  THR G OG1 1 
ATOM   6599 C CG2 . THR E 5 20  ? -3.655  -29.677 -53.221 1.00 38.93  ? 20  THR G CG2 1 
ATOM   6600 N N   . LEU E 5 21  ? -3.066  -30.630 -49.927 1.00 52.69  ? 21  LEU G N   1 
ATOM   6601 C CA  . LEU E 5 21  ? -3.748  -30.208 -48.712 1.00 50.39  ? 21  LEU G CA  1 
ATOM   6602 C C   . LEU E 5 21  ? -3.863  -28.690 -48.697 1.00 40.00  ? 21  LEU G C   1 
ATOM   6603 O O   . LEU E 5 21  ? -2.931  -27.984 -49.095 1.00 39.26  ? 21  LEU G O   1 
ATOM   6604 C CB  . LEU E 5 21  ? -3.003  -30.695 -47.464 1.00 38.31  ? 21  LEU G CB  1 
ATOM   6605 C CG  . LEU E 5 21  ? -2.385  -32.099 -47.486 1.00 47.09  ? 21  LEU G CG  1 
ATOM   6606 C CD1 . LEU E 5 21  ? -1.815  -32.452 -46.120 1.00 50.17  ? 21  LEU G CD1 1 
ATOM   6607 C CD2 . LEU E 5 21  ? -3.379  -33.157 -47.937 1.00 51.47  ? 21  LEU G CD2 1 
ATOM   6608 N N   . SER E 5 22  ? -5.005  -28.188 -48.234 1.00 33.32  ? 22  SER G N   1 
ATOM   6609 C CA  . SER E 5 22  ? -5.307  -26.766 -48.278 1.00 36.57  ? 22  SER G CA  1 
ATOM   6610 C C   . SER E 5 22  ? -5.432  -26.198 -46.870 1.00 46.12  ? 22  SER G C   1 
ATOM   6611 O O   . SER E 5 22  ? -5.703  -26.916 -45.903 1.00 49.20  ? 22  SER G O   1 
ATOM   6612 C CB  . SER E 5 22  ? -6.597  -26.493 -49.066 1.00 36.91  ? 22  SER G CB  1 
ATOM   6613 O OG  . SER E 5 22  ? -6.962  -25.124 -48.997 1.00 55.64  ? 22  SER G OG  1 
ATOM   6614 N N   . CYS E 5 23  ? -5.234  -24.884 -46.774 1.00 36.65  ? 23  CYS G N   1 
ATOM   6615 C CA  . CYS E 5 23  ? -5.279  -24.171 -45.499 1.00 46.31  ? 23  CYS G CA  1 
ATOM   6616 C C   . CYS E 5 23  ? -5.567  -22.707 -45.794 1.00 39.25  ? 23  CYS G C   1 
ATOM   6617 O O   . CYS E 5 23  ? -4.774  -22.051 -46.477 1.00 43.74  ? 23  CYS G O   1 
ATOM   6618 C CB  . CYS E 5 23  ? -3.954  -24.330 -44.737 1.00 49.06  ? 23  CYS G CB  1 
ATOM   6619 S SG  . CYS E 5 23  ? -3.772  -23.360 -43.202 1.00 73.13  ? 23  CYS G SG  1 
ATOM   6620 N N   . ARG E 5 24  ? -6.694  -22.199 -45.298 1.00 30.16  ? 24  ARG G N   1 
ATOM   6621 C CA  . ARG E 5 24  ? -7.077  -20.807 -45.487 1.00 41.09  ? 24  ARG G CA  1 
ATOM   6622 C C   . ARG E 5 24  ? -7.170  -20.108 -44.139 1.00 39.03  ? 24  ARG G C   1 
ATOM   6623 O O   . ARG E 5 24  ? -7.488  -20.728 -43.120 1.00 54.61  ? 24  ARG G O   1 
ATOM   6624 C CB  . ARG E 5 24  ? -8.414  -20.676 -46.231 1.00 55.97  ? 24  ARG G CB  1 
ATOM   6625 C CG  . ARG E 5 24  ? -8.384  -21.187 -47.660 1.00 54.97  ? 24  ARG G CG  1 
ATOM   6626 C CD  . ARG E 5 24  ? -9.019  -20.203 -48.636 1.00 67.59  ? 24  ARG G CD  1 
ATOM   6627 N NE  . ARG E 5 24  ? -8.048  -19.260 -49.180 1.00 76.91  ? 24  ARG G NE  1 
ATOM   6628 C CZ  . ARG E 5 24  ? -8.119  -17.941 -49.057 1.00 76.36  ? 24  ARG G CZ  1 
ATOM   6629 N NH1 . ARG E 5 24  ? -9.120  -17.359 -48.418 1.00 75.85  ? 24  ARG G NH1 1 
ATOM   6630 N NH2 . ARG E 5 24  ? -7.168  -17.187 -49.601 1.00 67.09  ? 24  ARG G NH2 1 
ATOM   6631 N N   . ALA E 5 25  ? -6.892  -18.807 -44.145 1.00 41.12  ? 25  ALA G N   1 
ATOM   6632 C CA  . ALA E 5 25  ? -6.815  -18.016 -42.928 1.00 42.20  ? 25  ALA G CA  1 
ATOM   6633 C C   . ALA E 5 25  ? -7.860  -16.908 -42.943 1.00 43.67  ? 25  ALA G C   1 
ATOM   6634 O O   . ALA E 5 25  ? -8.311  -16.469 -44.006 1.00 51.02  ? 25  ALA G O   1 
ATOM   6635 C CB  . ALA E 5 25  ? -5.419  -17.405 -42.750 1.00 51.39  ? 25  ALA G CB  1 
ATOM   6636 N N   . SER E 5 26  ? -8.241  -16.466 -41.743 1.00 46.24  ? 26  SER G N   1 
ATOM   6637 C CA  . SER E 5 26  ? -9.168  -15.345 -41.621 1.00 44.31  ? 26  SER G CA  1 
ATOM   6638 C C   . SER E 5 26  ? -8.584  -14.078 -42.231 1.00 58.85  ? 26  SER G C   1 
ATOM   6639 O O   . SER E 5 26  ? -9.287  -13.327 -42.916 1.00 66.66  ? 26  SER G O   1 
ATOM   6640 C CB  . SER E 5 26  ? -9.521  -15.119 -40.150 1.00 39.52  ? 26  SER G CB  1 
ATOM   6641 O OG  . SER E 5 26  ? -10.207 -13.893 -39.971 1.00 58.11  ? 26  SER G OG  1 
ATOM   6642 N N   . GLN E 5 27  ? -7.300  -13.824 -41.991 1.00 60.84  ? 27  GLN G N   1 
ATOM   6643 C CA  . GLN E 5 27  ? -6.608  -12.662 -42.523 1.00 58.89  ? 27  GLN G CA  1 
ATOM   6644 C C   . GLN E 5 27  ? -5.331  -13.112 -43.217 1.00 63.76  ? 27  GLN G C   1 
ATOM   6645 O O   . GLN E 5 27  ? -4.851  -14.230 -43.016 1.00 59.67  ? 27  GLN G O   1 
ATOM   6646 C CB  . GLN E 5 27  ? -6.268  -11.650 -41.421 1.00 52.62  ? 27  GLN G CB  1 
ATOM   6647 C CG  . GLN E 5 27  ? -7.423  -11.309 -40.499 1.00 61.77  ? 27  GLN G CG  1 
ATOM   6648 C CD  . GLN E 5 27  ? -6.989  -10.455 -39.325 1.00 62.32  ? 27  GLN G CD  1 
ATOM   6649 O OE1 . GLN E 5 27  ? -5.818  -10.093 -39.207 1.00 59.34  ? 27  GLN G OE1 1 
ATOM   6650 N NE2 . GLN E 5 27  ? -7.931  -10.129 -38.449 1.00 50.31  ? 27  GLN G NE2 1 
ATOM   6651 N N   . SER E 5 28  ? -4.784  -12.227 -44.044 1.00 56.75  ? 28  SER G N   1 
ATOM   6652 C CA  . SER E 5 28  ? -3.508  -12.503 -44.687 1.00 52.39  ? 28  SER G CA  1 
ATOM   6653 C C   . SER E 5 28  ? -2.392  -12.548 -43.650 1.00 61.14  ? 28  SER G C   1 
ATOM   6654 O O   . SER E 5 28  ? -2.357  -11.742 -42.716 1.00 59.71  ? 28  SER G O   1 
ATOM   6655 C CB  . SER E 5 28  ? -3.203  -11.441 -45.743 1.00 58.10  ? 28  SER G CB  1 
ATOM   6656 O OG  . SER E 5 28  ? -1.907  -11.620 -46.287 1.00 46.07  ? 28  SER G OG  1 
ATOM   6657 N N   . VAL E 5 29  ? -1.482  -13.505 -43.812 1.00 55.89  ? 29  VAL G N   1 
ATOM   6658 C CA  . VAL E 5 29  ? -0.337  -13.641 -42.918 1.00 51.44  ? 29  VAL G CA  1 
ATOM   6659 C C   . VAL E 5 29  ? 0.996   -13.530 -43.640 1.00 53.67  ? 29  VAL G C   1 
ATOM   6660 O O   . VAL E 5 29  ? 2.039   -13.485 -42.968 1.00 61.32  ? 29  VAL G O   1 
ATOM   6661 C CB  . VAL E 5 29  ? -0.398  -14.959 -42.115 1.00 48.87  ? 29  VAL G CB  1 
ATOM   6662 C CG1 . VAL E 5 29  ? -1.496  -14.885 -41.065 1.00 31.15  ? 29  VAL G CG1 1 
ATOM   6663 C CG2 . VAL E 5 29  ? -0.628  -16.135 -43.041 1.00 38.23  ? 29  VAL G CG2 1 
ATOM   6664 N N   . SER E 5 30  ? 1.002   -13.482 -44.972 1.00 38.43  ? 30  SER G N   1 
ATOM   6665 C CA  . SER E 5 30  ? 2.182   -13.163 -45.778 1.00 46.32  ? 30  SER G CA  1 
ATOM   6666 C C   . SER E 5 30  ? 3.366   -14.070 -45.429 1.00 47.62  ? 30  SER G C   1 
ATOM   6667 O O   . SER E 5 30  ? 4.397   -13.640 -44.909 1.00 57.42  ? 30  SER G O   1 
ATOM   6668 C CB  . SER E 5 30  ? 2.551   -11.682 -45.630 1.00 51.31  ? 30  SER G CB  1 
ATOM   6669 O OG  . SER E 5 30  ? 2.922   -11.367 -44.300 1.00 44.85  ? 30  SER G OG  1 
ATOM   6670 N N   . SER E 5 31  ? 3.169   -15.356 -45.722 1.00 43.07  ? 31  SER G N   1 
ATOM   6671 C CA  . SER E 5 31  ? 4.154   -16.428 -45.607 1.00 53.05  ? 31  SER G CA  1 
ATOM   6672 C C   . SER E 5 31  ? 4.525   -16.761 -44.168 1.00 37.06  ? 31  SER G C   1 
ATOM   6673 O O   . SER E 5 31  ? 5.392   -17.617 -43.955 1.00 34.07  ? 31  SER G O   1 
ATOM   6674 C CB  . SER E 5 31  ? 5.444   -16.129 -46.387 1.00 39.20  ? 31  SER G CB  1 
ATOM   6675 O OG  . SER E 5 31  ? 5.214   -16.156 -47.784 1.00 52.85  ? 31  SER G OG  1 
ATOM   6676 N N   . TYR E 5 32  ? 3.906   -16.125 -43.174 1.00 24.61  ? 32  TYR G N   1 
ATOM   6677 C CA  . TYR E 5 32  ? 4.154   -16.464 -41.773 1.00 31.87  ? 32  TYR G CA  1 
ATOM   6678 C C   . TYR E 5 32  ? 3.336   -17.699 -41.382 1.00 28.69  ? 32  TYR G C   1 
ATOM   6679 O O   . TYR E 5 32  ? 2.461   -17.661 -40.518 1.00 30.19  ? 32  TYR G O   1 
ATOM   6680 C CB  . TYR E 5 32  ? 3.827   -15.280 -40.871 1.00 41.56  ? 32  TYR G CB  1 
ATOM   6681 C CG  . TYR E 5 32  ? 4.690   -14.052 -41.077 1.00 42.80  ? 32  TYR G CG  1 
ATOM   6682 C CD1 . TYR E 5 32  ? 5.989   -14.155 -41.556 1.00 53.54  ? 32  TYR G CD1 1 
ATOM   6683 C CD2 . TYR E 5 32  ? 4.201   -12.785 -40.782 1.00 46.22  ? 32  TYR G CD2 1 
ATOM   6684 C CE1 . TYR E 5 32  ? 6.776   -13.028 -41.738 1.00 59.33  ? 32  TYR G CE1 1 
ATOM   6685 C CE2 . TYR E 5 32  ? 4.976   -11.656 -40.961 1.00 53.89  ? 32  TYR G CE2 1 
ATOM   6686 C CZ  . TYR E 5 32  ? 6.262   -11.781 -41.439 1.00 55.58  ? 32  TYR G CZ  1 
ATOM   6687 O OH  . TYR E 5 32  ? 7.033   -10.655 -41.616 1.00 49.99  ? 32  TYR G OH  1 
ATOM   6688 N N   . LEU E 5 33  ? 3.639   -18.814 -42.046 1.00 22.35  ? 33  LEU G N   1 
ATOM   6689 C CA  . LEU E 5 33  ? 2.876   -20.041 -41.879 1.00 17.05  ? 33  LEU G CA  1 
ATOM   6690 C C   . LEU E 5 33  ? 3.818   -21.238 -41.885 1.00 27.29  ? 33  LEU G C   1 
ATOM   6691 O O   . LEU E 5 33  ? 4.901   -21.192 -42.473 1.00 37.59  ? 33  LEU G O   1 
ATOM   6692 C CB  . LEU E 5 33  ? 1.819   -20.187 -42.983 1.00 28.66  ? 33  LEU G CB  1 
ATOM   6693 C CG  . LEU E 5 33  ? 0.817   -21.337 -42.871 1.00 28.94  ? 33  LEU G CG  1 
ATOM   6694 C CD1 . LEU E 5 33  ? -0.608  -20.811 -42.825 1.00 30.04  ? 33  LEU G CD1 1 
ATOM   6695 C CD2 . LEU E 5 33  ? 1.000   -22.304 -44.025 1.00 25.67  ? 33  LEU G CD2 1 
ATOM   6696 N N   . ALA E 5 34  ? 3.391   -22.313 -41.223 1.00 32.53  ? 34  ALA G N   1 
ATOM   6697 C CA  . ALA E 5 34  ? 4.175   -23.535 -41.128 1.00 25.33  ? 34  ALA G CA  1 
ATOM   6698 C C   . ALA E 5 34  ? 3.248   -24.742 -41.187 1.00 27.51  ? 34  ALA G C   1 
ATOM   6699 O O   . ALA E 5 34  ? 2.043   -24.638 -40.947 1.00 26.31  ? 34  ALA G O   1 
ATOM   6700 C CB  . ALA E 5 34  ? 5.014   -23.572 -39.843 1.00 26.85  ? 34  ALA G CB  1 
ATOM   6701 N N   . TRP E 5 35  ? 3.831   -25.897 -41.512 1.00 27.74  ? 35  TRP G N   1 
ATOM   6702 C CA  . TRP E 5 35  ? 3.101   -27.152 -41.623 1.00 30.67  ? 35  TRP G CA  1 
ATOM   6703 C C   . TRP E 5 35  ? 3.739   -28.204 -40.728 1.00 34.22  ? 35  TRP G C   1 
ATOM   6704 O O   . TRP E 5 35  ? 4.967   -28.286 -40.630 1.00 29.01  ? 35  TRP G O   1 
ATOM   6705 C CB  . TRP E 5 35  ? 3.071   -27.658 -43.071 1.00 33.39  ? 35  TRP G CB  1 
ATOM   6706 C CG  . TRP E 5 35  ? 2.213   -26.838 -43.983 1.00 39.78  ? 35  TRP G CG  1 
ATOM   6707 C CD1 . TRP E 5 35  ? 2.585   -25.726 -44.678 1.00 39.63  ? 35  TRP G CD1 1 
ATOM   6708 C CD2 . TRP E 5 35  ? 0.835   -27.070 -44.304 1.00 45.35  ? 35  TRP G CD2 1 
ATOM   6709 N NE1 . TRP E 5 35  ? 1.526   -25.249 -45.411 1.00 39.20  ? 35  TRP G NE1 1 
ATOM   6710 C CE2 . TRP E 5 35  ? 0.439   -26.056 -45.198 1.00 47.62  ? 35  TRP G CE2 1 
ATOM   6711 C CE3 . TRP E 5 35  ? -0.101  -28.035 -43.921 1.00 37.43  ? 35  TRP G CE3 1 
ATOM   6712 C CZ2 . TRP E 5 35  ? -0.852  -25.980 -45.716 1.00 40.22  ? 35  TRP G CZ2 1 
ATOM   6713 C CZ3 . TRP E 5 35  ? -1.382  -27.958 -44.436 1.00 36.54  ? 35  TRP G CZ3 1 
ATOM   6714 C CH2 . TRP E 5 35  ? -1.745  -26.938 -45.324 1.00 41.02  ? 35  TRP G CH2 1 
ATOM   6715 N N   . TYR E 5 36  ? 2.899   -29.014 -40.086 1.00 30.42  ? 36  TYR G N   1 
ATOM   6716 C CA  . TYR E 5 36  ? 3.357   -30.054 -39.177 1.00 25.77  ? 36  TYR G CA  1 
ATOM   6717 C C   . TYR E 5 36  ? 2.698   -31.381 -39.525 1.00 29.98  ? 36  TYR G C   1 
ATOM   6718 O O   . TYR E 5 36  ? 1.555   -31.425 -39.987 1.00 34.37  ? 36  TYR G O   1 
ATOM   6719 C CB  . TYR E 5 36  ? 3.054   -29.701 -37.715 1.00 19.63  ? 36  TYR G CB  1 
ATOM   6720 C CG  . TYR E 5 36  ? 3.643   -28.386 -37.260 1.00 22.05  ? 36  TYR G CG  1 
ATOM   6721 C CD1 . TYR E 5 36  ? 2.936   -27.200 -37.405 1.00 22.67  ? 36  TYR G CD1 1 
ATOM   6722 C CD2 . TYR E 5 36  ? 4.903   -28.331 -36.680 1.00 21.78  ? 36  TYR G CD2 1 
ATOM   6723 C CE1 . TYR E 5 36  ? 3.468   -25.997 -36.988 1.00 31.92  ? 36  TYR G CE1 1 
ATOM   6724 C CE2 . TYR E 5 36  ? 5.444   -27.132 -36.259 1.00 19.10  ? 36  TYR G CE2 1 
ATOM   6725 C CZ  . TYR E 5 36  ? 4.722   -25.968 -36.415 1.00 25.93  ? 36  TYR G CZ  1 
ATOM   6726 O OH  . TYR E 5 36  ? 5.258   -24.771 -35.998 1.00 20.32  ? 36  TYR G OH  1 
ATOM   6727 N N   . GLN E 5 37  ? 3.437   -32.464 -39.295 1.00 26.21  ? 37  GLN G N   1 
ATOM   6728 C CA  . GLN E 5 37  ? 2.945   -33.826 -39.470 1.00 34.05  ? 37  GLN G CA  1 
ATOM   6729 C C   . GLN E 5 37  ? 2.945   -34.517 -38.115 1.00 37.68  ? 37  GLN G C   1 
ATOM   6730 O O   . GLN E 5 37  ? 3.987   -34.589 -37.454 1.00 38.56  ? 37  GLN G O   1 
ATOM   6731 C CB  . GLN E 5 37  ? 3.813   -34.599 -40.465 1.00 28.17  ? 37  GLN G CB  1 
ATOM   6732 C CG  . GLN E 5 37  ? 3.469   -36.075 -40.577 1.00 26.09  ? 37  GLN G CG  1 
ATOM   6733 C CD  . GLN E 5 37  ? 4.556   -36.876 -41.269 1.00 40.63  ? 37  GLN G CD  1 
ATOM   6734 O OE1 . GLN E 5 37  ? 5.675   -36.987 -40.768 1.00 36.16  ? 37  GLN G OE1 1 
ATOM   6735 N NE2 . GLN E 5 37  ? 4.231   -37.438 -42.428 1.00 46.31  ? 37  GLN G NE2 1 
ATOM   6736 N N   . GLN E 5 38  ? 1.786   -35.029 -37.704 1.00 30.69  ? 38  GLN G N   1 
ATOM   6737 C CA  . GLN E 5 38  ? 1.644   -35.718 -36.422 1.00 38.98  ? 38  GLN G CA  1 
ATOM   6738 C C   . GLN E 5 38  ? 1.105   -37.123 -36.669 1.00 34.09  ? 38  GLN G C   1 
ATOM   6739 O O   . GLN E 5 38  ? -0.095  -37.308 -36.895 1.00 38.12  ? 38  GLN G O   1 
ATOM   6740 C CB  . GLN E 5 38  ? 0.735   -34.947 -35.469 1.00 27.40  ? 38  GLN G CB  1 
ATOM   6741 C CG  . GLN E 5 38  ? 0.595   -35.618 -34.109 1.00 22.02  ? 38  GLN G CG  1 
ATOM   6742 C CD  . GLN E 5 38  ? -0.244  -34.819 -33.134 1.00 26.51  ? 38  GLN G CD  1 
ATOM   6743 O OE1 . GLN E 5 38  ? -1.194  -34.141 -33.523 1.00 31.03  ? 38  GLN G OE1 1 
ATOM   6744 N NE2 . GLN E 5 38  ? 0.106   -34.894 -31.855 1.00 25.35  ? 38  GLN G NE2 1 
ATOM   6745 N N   . LYS E 5 39  ? 1.996   -38.107 -36.620 1.00 34.10  ? 39  LYS G N   1 
ATOM   6746 C CA  . LYS E 5 39  ? 1.612   -39.504 -36.684 1.00 42.58  ? 39  LYS G CA  1 
ATOM   6747 C C   . LYS E 5 39  ? 1.008   -39.938 -35.350 1.00 54.96  ? 39  LYS G C   1 
ATOM   6748 O O   . LYS E 5 39  ? 1.274   -39.326 -34.313 1.00 43.65  ? 39  LYS G O   1 
ATOM   6749 C CB  . LYS E 5 39  ? 2.826   -40.355 -37.041 1.00 42.26  ? 39  LYS G CB  1 
ATOM   6750 C CG  . LYS E 5 39  ? 3.573   -39.831 -38.257 1.00 37.86  ? 39  LYS G CG  1 
ATOM   6751 C CD  . LYS E 5 39  ? 4.487   -40.876 -38.865 1.00 41.13  ? 39  LYS G CD  1 
ATOM   6752 C CE  . LYS E 5 39  ? 5.208   -40.317 -40.083 1.00 38.16  ? 39  LYS G CE  1 
ATOM   6753 N NZ  . LYS E 5 39  ? 5.859   -41.385 -40.893 1.00 49.97  ? 39  LYS G NZ  1 
ATOM   6754 N N   . PRO E 5 40  ? 0.165   -40.974 -35.353 1.00 57.84  ? 40  PRO G N   1 
ATOM   6755 C CA  . PRO E 5 40  ? -0.514  -41.371 -34.112 1.00 49.42  ? 40  PRO G CA  1 
ATOM   6756 C C   . PRO E 5 40  ? 0.471   -41.737 -33.009 1.00 46.95  ? 40  PRO G C   1 
ATOM   6757 O O   . PRO E 5 40  ? 1.467   -42.427 -33.238 1.00 54.09  ? 40  PRO G O   1 
ATOM   6758 C CB  . PRO E 5 40  ? -1.352  -42.580 -34.540 1.00 59.91  ? 40  PRO G CB  1 
ATOM   6759 C CG  . PRO E 5 40  ? -1.566  -42.391 -36.000 1.00 60.19  ? 40  PRO G CG  1 
ATOM   6760 C CD  . PRO E 5 40  ? -0.307  -41.754 -36.511 1.00 51.42  ? 40  PRO G CD  1 
ATOM   6761 N N   . GLY E 5 41  ? 0.175   -41.264 -31.799 1.00 45.36  ? 41  GLY G N   1 
ATOM   6762 C CA  . GLY E 5 41  ? 0.991   -41.556 -30.638 1.00 43.75  ? 41  GLY G CA  1 
ATOM   6763 C C   . GLY E 5 41  ? 2.300   -40.806 -30.563 1.00 50.42  ? 41  GLY G C   1 
ATOM   6764 O O   . GLY E 5 41  ? 3.109   -41.095 -29.674 1.00 56.47  ? 41  GLY G O   1 
ATOM   6765 N N   . GLN E 5 42  ? 2.534   -39.847 -31.455 1.00 43.40  ? 42  GLN G N   1 
ATOM   6766 C CA  . GLN E 5 42  ? 3.809   -39.153 -31.543 1.00 35.90  ? 42  GLN G CA  1 
ATOM   6767 C C   . GLN E 5 42  ? 3.579   -37.651 -31.630 1.00 33.60  ? 42  GLN G C   1 
ATOM   6768 O O   . GLN E 5 42  ? 2.491   -37.183 -31.972 1.00 34.10  ? 42  GLN G O   1 
ATOM   6769 C CB  . GLN E 5 42  ? 4.625   -39.633 -32.752 1.00 35.55  ? 42  GLN G CB  1 
ATOM   6770 C CG  . GLN E 5 42  ? 4.968   -41.113 -32.713 1.00 46.71  ? 42  GLN G CG  1 
ATOM   6771 C CD  . GLN E 5 42  ? 5.695   -41.579 -33.957 1.00 65.93  ? 42  GLN G CD  1 
ATOM   6772 O OE1 . GLN E 5 42  ? 5.519   -41.020 -35.039 1.00 54.09  ? 42  GLN G OE1 1 
ATOM   6773 N NE2 . GLN E 5 42  ? 6.522   -42.607 -33.807 1.00 73.84  ? 42  GLN G NE2 1 
ATOM   6774 N N   . ALA E 5 43  ? 4.628   -36.901 -31.304 1.00 34.87  ? 43  ALA G N   1 
ATOM   6775 C CA  . ALA E 5 43  ? 4.593   -35.450 -31.329 1.00 32.53  ? 43  ALA G CA  1 
ATOM   6776 C C   . ALA E 5 43  ? 4.620   -34.930 -32.763 1.00 36.24  ? 43  ALA G C   1 
ATOM   6777 O O   . ALA E 5 43  ? 5.071   -35.625 -33.677 1.00 32.48  ? 43  ALA G O   1 
ATOM   6778 C CB  . ALA E 5 43  ? 5.776   -34.887 -30.548 1.00 31.51  ? 43  ALA G CB  1 
ATOM   6779 N N   . PRO E 5 44  ? 4.124   -33.713 -32.989 1.00 35.57  ? 44  PRO G N   1 
ATOM   6780 C CA  . PRO E 5 44  ? 4.200   -33.127 -34.333 1.00 31.88  ? 44  PRO G CA  1 
ATOM   6781 C C   . PRO E 5 44  ? 5.641   -32.970 -34.800 1.00 36.75  ? 44  PRO G C   1 
ATOM   6782 O O   . PRO E 5 44  ? 6.543   -32.675 -34.014 1.00 33.57  ? 44  PRO G O   1 
ATOM   6783 C CB  . PRO E 5 44  ? 3.512   -31.767 -34.167 1.00 28.78  ? 44  PRO G CB  1 
ATOM   6784 C CG  . PRO E 5 44  ? 2.613   -31.941 -32.996 1.00 27.18  ? 44  PRO G CG  1 
ATOM   6785 C CD  . PRO E 5 44  ? 3.329   -32.879 -32.070 1.00 28.73  ? 44  PRO G CD  1 
ATOM   6786 N N   . ARG E 5 45  ? 5.847   -33.178 -36.098 1.00 39.52  ? 45  ARG G N   1 
ATOM   6787 C CA  . ARG E 5 45  ? 7.140   -32.989 -36.742 1.00 32.96  ? 45  ARG G CA  1 
ATOM   6788 C C   . ARG E 5 45  ? 7.029   -31.838 -37.731 1.00 38.03  ? 45  ARG G C   1 
ATOM   6789 O O   . ARG E 5 45  ? 6.096   -31.798 -38.540 1.00 43.36  ? 45  ARG G O   1 
ATOM   6790 C CB  . ARG E 5 45  ? 7.592   -34.264 -37.459 1.00 32.62  ? 45  ARG G CB  1 
ATOM   6791 C CG  . ARG E 5 45  ? 8.920   -34.128 -38.191 1.00 45.47  ? 45  ARG G CG  1 
ATOM   6792 C CD  . ARG E 5 45  ? 9.346   -35.437 -38.849 1.00 50.29  ? 45  ARG G CD  1 
ATOM   6793 N NE  . ARG E 5 45  ? 8.583   -35.736 -40.055 1.00 69.71  ? 45  ARG G NE  1 
ATOM   6794 C CZ  . ARG E 5 45  ? 8.846   -36.744 -40.877 1.00 58.83  ? 45  ARG G CZ  1 
ATOM   6795 N NH1 . ARG E 5 45  ? 9.847   -37.578 -40.649 1.00 50.64  ? 45  ARG G NH1 1 
ATOM   6796 N NH2 . ARG E 5 45  ? 8.087   -36.917 -41.956 1.00 42.48  ? 45  ARG G NH2 1 
ATOM   6797 N N   . LEU E 5 46  ? 7.974   -30.903 -37.662 1.00 44.97  ? 46  LEU G N   1 
ATOM   6798 C CA  . LEU E 5 46  ? 7.946   -29.754 -38.558 1.00 39.62  ? 46  LEU G CA  1 
ATOM   6799 C C   . LEU E 5 46  ? 8.340   -30.175 -39.968 1.00 34.91  ? 46  LEU G C   1 
ATOM   6800 O O   . LEU E 5 46  ? 9.378   -30.811 -40.173 1.00 33.34  ? 46  LEU G O   1 
ATOM   6801 C CB  . LEU E 5 46  ? 8.883   -28.660 -38.051 1.00 41.81  ? 46  LEU G CB  1 
ATOM   6802 C CG  . LEU E 5 46  ? 8.986   -27.411 -38.931 1.00 32.48  ? 46  LEU G CG  1 
ATOM   6803 C CD1 . LEU E 5 46  ? 7.662   -26.666 -38.980 1.00 27.93  ? 46  LEU G CD1 1 
ATOM   6804 C CD2 . LEU E 5 46  ? 10.102  -26.499 -38.450 1.00 27.64  ? 46  LEU G CD2 1 
ATOM   6805 N N   . LEU E 5 47  ? 7.503   -29.818 -40.942 1.00 31.72  ? 47  LEU G N   1 
ATOM   6806 C CA  . LEU E 5 47  ? 7.757   -30.095 -42.350 1.00 36.89  ? 47  LEU G CA  1 
ATOM   6807 C C   . LEU E 5 47  ? 8.142   -28.849 -43.129 1.00 38.38  ? 47  LEU G C   1 
ATOM   6808 O O   . LEU E 5 47  ? 9.187   -28.823 -43.786 1.00 40.49  ? 47  LEU G O   1 
ATOM   6809 C CB  . LEU E 5 47  ? 6.519   -30.734 -42.998 1.00 39.27  ? 47  LEU G CB  1 
ATOM   6810 C CG  . LEU E 5 47  ? 6.094   -32.136 -42.563 1.00 40.40  ? 47  LEU G CG  1 
ATOM   6811 C CD1 . LEU E 5 47  ? 4.782   -32.510 -43.234 1.00 49.46  ? 47  LEU G CD1 1 
ATOM   6812 C CD2 . LEU E 5 47  ? 7.174   -33.153 -42.891 1.00 44.89  ? 47  LEU G CD2 1 
ATOM   6813 N N   . ILE E 5 48  ? 7.317   -27.808 -43.068 1.00 30.83  ? 48  ILE G N   1 
ATOM   6814 C CA  . ILE E 5 48  ? 7.501   -26.597 -43.854 1.00 32.49  ? 48  ILE G CA  1 
ATOM   6815 C C   . ILE E 5 48  ? 7.454   -25.402 -42.916 1.00 35.74  ? 48  ILE G C   1 
ATOM   6816 O O   . ILE E 5 48  ? 6.633   -25.359 -41.994 1.00 33.17  ? 48  ILE G O   1 
ATOM   6817 C CB  . ILE E 5 48  ? 6.426   -26.467 -44.955 1.00 36.43  ? 48  ILE G CB  1 
ATOM   6818 C CG1 . ILE E 5 48  ? 6.410   -27.713 -45.842 1.00 36.89  ? 48  ILE G CG1 1 
ATOM   6819 C CG2 . ILE E 5 48  ? 6.654   -25.218 -45.795 1.00 39.20  ? 48  ILE G CG2 1 
ATOM   6820 C CD1 . ILE E 5 48  ? 7.707   -27.957 -46.575 1.00 31.90  ? 48  ILE G CD1 1 
ATOM   6821 N N   . TYR E 5 49  ? 8.349   -24.443 -43.136 1.00 35.84  ? 49  TYR G N   1 
ATOM   6822 C CA  . TYR E 5 49  ? 8.300   -23.158 -42.457 1.00 29.85  ? 49  TYR G CA  1 
ATOM   6823 C C   . TYR E 5 49  ? 8.434   -22.052 -43.493 1.00 33.36  ? 49  TYR G C   1 
ATOM   6824 O O   . TYR E 5 49  ? 9.044   -22.240 -44.548 1.00 40.91  ? 49  TYR G O   1 
ATOM   6825 C CB  . TYR E 5 49  ? 9.392   -23.023 -41.387 1.00 28.19  ? 49  TYR G CB  1 
ATOM   6826 C CG  . TYR E 5 49  ? 10.802  -22.992 -41.925 1.00 27.21  ? 49  TYR G CG  1 
ATOM   6827 C CD1 . TYR E 5 49  ? 11.496  -24.169 -42.167 1.00 33.94  ? 49  TYR G CD1 1 
ATOM   6828 C CD2 . TYR E 5 49  ? 11.448  -21.786 -42.174 1.00 27.89  ? 49  TYR G CD2 1 
ATOM   6829 C CE1 . TYR E 5 49  ? 12.785  -24.150 -42.652 1.00 32.63  ? 49  TYR G CE1 1 
ATOM   6830 C CE2 . TYR E 5 49  ? 12.741  -21.757 -42.661 1.00 27.48  ? 49  TYR G CE2 1 
ATOM   6831 C CZ  . TYR E 5 49  ? 13.405  -22.945 -42.897 1.00 34.10  ? 49  TYR G CZ  1 
ATOM   6832 O OH  . TYR E 5 49  ? 14.693  -22.937 -43.381 1.00 33.29  ? 49  TYR G OH  1 
ATOM   6833 N N   . GLY E 5 50  ? 7.844   -20.899 -43.190 1.00 32.25  ? 50  GLY G N   1 
ATOM   6834 C CA  . GLY E 5 50  ? 7.804   -19.820 -44.152 1.00 25.19  ? 50  GLY G CA  1 
ATOM   6835 C C   . GLY E 5 50  ? 6.937   -20.087 -45.368 1.00 48.02  ? 50  GLY G C   1 
ATOM   6836 O O   . GLY E 5 50  ? 7.116   -19.425 -46.392 1.00 48.74  ? 50  GLY G O   1 
ATOM   6837 N N   . ALA E 5 51  ? 6.034   -21.069 -45.300 1.00 51.97  ? 51  ALA G N   1 
ATOM   6838 C CA  . ALA E 5 51  ? 5.155   -21.567 -46.366 1.00 39.22  ? 51  ALA G CA  1 
ATOM   6839 C C   . ALA E 5 51  ? 5.896   -22.111 -47.589 1.00 41.05  ? 51  ALA G C   1 
ATOM   6840 O O   . ALA E 5 51  ? 5.242   -22.591 -48.524 1.00 57.33  ? 51  ALA G O   1 
ATOM   6841 C CB  . ALA E 5 51  ? 4.143   -20.515 -46.849 1.00 29.35  ? 51  ALA G CB  1 
ATOM   6842 N N   . SER E 5 52  ? 7.225   -22.028 -47.638 1.00 39.11  ? 52  SER G N   1 
ATOM   6843 C CA  . SER E 5 52  ? 7.953   -22.605 -48.764 1.00 39.48  ? 52  SER G CA  1 
ATOM   6844 C C   . SER E 5 52  ? 9.163   -23.443 -48.379 1.00 46.21  ? 52  SER G C   1 
ATOM   6845 O O   . SER E 5 52  ? 9.601   -24.256 -49.200 1.00 52.99  ? 52  SER G O   1 
ATOM   6846 C CB  . SER E 5 52  ? 8.413   -21.501 -49.730 1.00 33.66  ? 52  SER G CB  1 
ATOM   6847 O OG  . SER E 5 52  ? 7.328   -20.667 -50.108 1.00 49.25  ? 52  SER G OG  1 
ATOM   6848 N N   . SER E 5 53  ? 9.729   -23.291 -47.183 1.00 32.36  ? 53  SER G N   1 
ATOM   6849 C CA  . SER E 5 53  ? 11.028  -23.870 -46.854 1.00 38.07  ? 53  SER G CA  1 
ATOM   6850 C C   . SER E 5 53  ? 10.875  -25.198 -46.119 1.00 38.09  ? 53  SER G C   1 
ATOM   6851 O O   . SER E 5 53  ? 10.133  -25.289 -45.136 1.00 47.72  ? 53  SER G O   1 
ATOM   6852 C CB  . SER E 5 53  ? 11.849  -22.898 -46.005 1.00 41.11  ? 53  SER G CB  1 
ATOM   6853 O OG  . SER E 5 53  ? 11.928  -21.624 -46.621 1.00 36.77  ? 53  SER G OG  1 
ATOM   6854 N N   . ARG E 5 54  ? 11.595  -26.218 -46.583 1.00 34.97  ? 54  ARG G N   1 
ATOM   6855 C CA  . ARG E 5 54  ? 11.559  -27.523 -45.937 1.00 39.92  ? 54  ARG G CA  1 
ATOM   6856 C C   . ARG E 5 54  ? 12.525  -27.568 -44.761 1.00 45.02  ? 54  ARG G C   1 
ATOM   6857 O O   . ARG E 5 54  ? 13.631  -27.024 -44.823 1.00 51.18  ? 54  ARG G O   1 
ATOM   6858 C CB  . ARG E 5 54  ? 11.903  -28.629 -46.935 1.00 41.73  ? 54  ARG G CB  1 
ATOM   6859 C CG  . ARG E 5 54  ? 10.909  -28.767 -48.071 1.00 53.34  ? 54  ARG G CG  1 
ATOM   6860 C CD  . ARG E 5 54  ? 11.145  -30.037 -48.870 1.00 60.67  ? 54  ARG G CD  1 
ATOM   6861 N NE  . ARG E 5 54  ? 12.290  -29.929 -49.765 1.00 64.16  ? 54  ARG G NE  1 
ATOM   6862 C CZ  . ARG E 5 54  ? 12.247  -29.374 -50.969 1.00 74.17  ? 54  ARG G CZ  1 
ATOM   6863 N NH1 . ARG E 5 54  ? 11.135  -28.835 -51.442 1.00 68.95  ? 54  ARG G NH1 1 
ATOM   6864 N NH2 . ARG E 5 54  ? 13.347  -29.359 -51.716 1.00 78.91  ? 54  ARG G NH2 1 
ATOM   6865 N N   . ALA E 5 55  ? 12.097  -28.222 -43.685 1.00 44.41  ? 55  ALA G N   1 
ATOM   6866 C CA  . ALA E 5 55  ? 12.949  -28.405 -42.523 1.00 41.42  ? 55  ALA G CA  1 
ATOM   6867 C C   . ALA E 5 55  ? 14.009  -29.467 -42.806 1.00 47.90  ? 55  ALA G C   1 
ATOM   6868 O O   . ALA E 5 55  ? 13.925  -30.232 -43.771 1.00 51.26  ? 55  ALA G O   1 
ATOM   6869 C CB  . ALA E 5 55  ? 12.118  -28.788 -41.300 1.00 43.57  ? 55  ALA G CB  1 
ATOM   6870 N N   . THR E 5 56  ? 15.024  -29.503 -41.946 1.00 50.15  ? 56  THR G N   1 
ATOM   6871 C CA  . THR E 5 56  ? 16.126  -30.437 -42.129 1.00 52.76  ? 56  THR G CA  1 
ATOM   6872 C C   . THR E 5 56  ? 15.648  -31.878 -41.992 1.00 54.49  ? 56  THR G C   1 
ATOM   6873 O O   . THR E 5 56  ? 14.805  -32.196 -41.149 1.00 54.40  ? 56  THR G O   1 
ATOM   6874 C CB  . THR E 5 56  ? 17.238  -30.152 -41.117 1.00 60.53  ? 56  THR G CB  1 
ATOM   6875 O OG1 . THR E 5 56  ? 18.196  -31.217 -41.143 1.00 74.55  ? 56  THR G OG1 1 
ATOM   6876 C CG2 . THR E 5 56  ? 16.664  -30.016 -39.712 1.00 44.72  ? 56  THR G CG2 1 
ATOM   6877 N N   . GLY E 5 57  ? 16.190  -32.752 -42.838 1.00 57.26  ? 57  GLY G N   1 
ATOM   6878 C CA  . GLY E 5 57  ? 15.834  -34.154 -42.826 1.00 59.95  ? 57  GLY G CA  1 
ATOM   6879 C C   . GLY E 5 57  ? 14.532  -34.496 -43.514 1.00 60.14  ? 57  GLY G C   1 
ATOM   6880 O O   . GLY E 5 57  ? 14.126  -35.665 -43.487 1.00 63.08  ? 57  GLY G O   1 
ATOM   6881 N N   . ILE E 5 58  ? 13.864  -33.525 -44.129 1.00 59.74  ? 58  ILE G N   1 
ATOM   6882 C CA  . ILE E 5 58  ? 12.573  -33.753 -44.771 1.00 55.73  ? 58  ILE G CA  1 
ATOM   6883 C C   . ILE E 5 58  ? 12.785  -34.078 -46.245 1.00 66.08  ? 58  ILE G C   1 
ATOM   6884 O O   . ILE E 5 58  ? 13.522  -33.362 -46.938 1.00 63.45  ? 58  ILE G O   1 
ATOM   6885 C CB  . ILE E 5 58  ? 11.644  -32.542 -44.590 1.00 51.46  ? 58  ILE G CB  1 
ATOM   6886 C CG1 . ILE E 5 58  ? 11.285  -32.371 -43.110 1.00 50.54  ? 58  ILE G CG1 1 
ATOM   6887 C CG2 . ILE E 5 58  ? 10.402  -32.673 -45.464 1.00 50.98  ? 58  ILE G CG2 1 
ATOM   6888 C CD1 . ILE E 5 58  ? 10.939  -33.671 -42.400 1.00 48.54  ? 58  ILE G CD1 1 
ATOM   6889 N N   . PRO E 5 59  ? 12.175  -35.147 -46.758 1.00 71.50  ? 59  PRO G N   1 
ATOM   6890 C CA  . PRO E 5 59  ? 12.339  -35.483 -48.177 1.00 68.57  ? 59  PRO G CA  1 
ATOM   6891 C C   . PRO E 5 59  ? 11.775  -34.396 -49.080 1.00 67.03  ? 59  PRO G C   1 
ATOM   6892 O O   . PRO E 5 59  ? 10.856  -33.661 -48.710 1.00 57.71  ? 59  PRO G O   1 
ATOM   6893 C CB  . PRO E 5 59  ? 11.557  -36.794 -48.325 1.00 65.37  ? 59  PRO G CB  1 
ATOM   6894 C CG  . PRO E 5 59  ? 11.489  -37.358 -46.939 1.00 67.91  ? 59  PRO G CG  1 
ATOM   6895 C CD  . PRO E 5 59  ? 11.406  -36.170 -46.031 1.00 65.83  ? 59  PRO G CD  1 
ATOM   6896 N N   . ASP E 5 60  ? 12.350  -34.298 -50.282 1.00 76.15  ? 60  ASP G N   1 
ATOM   6897 C CA  . ASP E 5 60  ? 11.948  -33.265 -51.230 1.00 72.99  ? 60  ASP G CA  1 
ATOM   6898 C C   . ASP E 5 60  ? 10.514  -33.438 -51.710 1.00 70.42  ? 60  ASP G C   1 
ATOM   6899 O O   . ASP E 5 60  ? 9.930   -32.483 -52.236 1.00 62.99  ? 60  ASP G O   1 
ATOM   6900 C CB  . ASP E 5 60  ? 12.893  -33.262 -52.433 1.00 87.65  ? 60  ASP G CB  1 
ATOM   6901 C CG  . ASP E 5 60  ? 14.350  -33.167 -52.029 1.00 99.28  ? 60  ASP G CG  1 
ATOM   6902 O OD1 . ASP E 5 60  ? 14.629  -33.075 -50.816 1.00 101.02 ? 60  ASP G OD1 1 
ATOM   6903 O OD2 . ASP E 5 60  ? 15.217  -33.186 -52.927 1.00 102.48 ? 60  ASP G OD2 1 
ATOM   6904 N N   . ARG E 5 61  ? 9.938   -34.632 -51.548 1.00 73.42  ? 61  ARG G N   1 
ATOM   6905 C CA  . ARG E 5 61  ? 8.586   -34.880 -52.037 1.00 59.50  ? 61  ARG G CA  1 
ATOM   6906 C C   . ARG E 5 61  ? 7.559   -34.002 -51.332 1.00 65.46  ? 61  ARG G C   1 
ATOM   6907 O O   . ARG E 5 61  ? 6.546   -33.627 -51.935 1.00 60.90  ? 61  ARG G O   1 
ATOM   6908 C CB  . ARG E 5 61  ? 8.242   -36.360 -51.877 1.00 55.49  ? 61  ARG G CB  1 
ATOM   6909 C CG  . ARG E 5 61  ? 8.565   -36.934 -50.509 1.00 59.64  ? 61  ARG G CG  1 
ATOM   6910 C CD  . ARG E 5 61  ? 8.523   -38.454 -50.538 1.00 61.09  ? 61  ARG G CD  1 
ATOM   6911 N NE  . ARG E 5 61  ? 8.438   -39.029 -49.201 1.00 69.80  ? 61  ARG G NE  1 
ATOM   6912 C CZ  . ARG E 5 61  ? 7.312   -39.151 -48.510 1.00 70.82  ? 61  ARG G CZ  1 
ATOM   6913 N NH1 . ARG E 5 61  ? 6.155   -38.730 -48.994 1.00 61.99  ? 61  ARG G NH1 1 
ATOM   6914 N NH2 . ARG E 5 61  ? 7.348   -39.706 -47.302 1.00 68.32  ? 61  ARG G NH2 1 
ATOM   6915 N N   . PHE E 5 62  ? 7.794   -33.667 -50.066 1.00 69.59  ? 62  PHE G N   1 
ATOM   6916 C CA  . PHE E 5 62  ? 6.957   -32.686 -49.389 1.00 65.03  ? 62  PHE G CA  1 
ATOM   6917 C C   . PHE E 5 62  ? 7.226   -31.302 -49.967 1.00 54.99  ? 62  PHE G C   1 
ATOM   6918 O O   . PHE E 5 62  ? 8.383   -30.902 -50.130 1.00 56.12  ? 62  PHE G O   1 
ATOM   6919 C CB  . PHE E 5 62  ? 7.228   -32.695 -47.885 1.00 58.26  ? 62  PHE G CB  1 
ATOM   6920 C CG  . PHE E 5 62  ? 6.848   -33.980 -47.203 1.00 56.82  ? 62  PHE G CG  1 
ATOM   6921 C CD1 . PHE E 5 62  ? 7.740   -35.039 -47.139 1.00 63.64  ? 62  PHE G CD1 1 
ATOM   6922 C CD2 . PHE E 5 62  ? 5.601   -34.126 -46.618 1.00 53.86  ? 62  PHE G CD2 1 
ATOM   6923 C CE1 . PHE E 5 62  ? 7.393   -36.221 -46.510 1.00 57.36  ? 62  PHE G CE1 1 
ATOM   6924 C CE2 . PHE E 5 62  ? 5.249   -35.305 -45.988 1.00 52.65  ? 62  PHE G CE2 1 
ATOM   6925 C CZ  . PHE E 5 62  ? 6.146   -36.354 -45.934 1.00 49.56  ? 62  PHE G CZ  1 
ATOM   6926 N N   . SER E 5 63  ? 6.161   -30.572 -50.285 1.00 48.85  ? 63  SER G N   1 
ATOM   6927 C CA  . SER E 5 63  ? 6.296   -29.245 -50.871 1.00 49.74  ? 63  SER G CA  1 
ATOM   6928 C C   . SER E 5 63  ? 5.211   -28.333 -50.326 1.00 45.29  ? 63  SER G C   1 
ATOM   6929 O O   . SER E 5 63  ? 4.039   -28.718 -50.274 1.00 51.33  ? 63  SER G O   1 
ATOM   6930 C CB  . SER E 5 63  ? 6.221   -29.305 -52.401 1.00 57.66  ? 63  SER G CB  1 
ATOM   6931 O OG  . SER E 5 63  ? 7.286   -30.074 -52.934 1.00 58.98  ? 63  SER G OG  1 
ATOM   6932 N N   . GLY E 5 64  ? 5.606   -27.128 -49.923 1.00 42.63  ? 64  GLY G N   1 
ATOM   6933 C CA  . GLY E 5 64  ? 4.680   -26.114 -49.457 1.00 35.47  ? 64  GLY G CA  1 
ATOM   6934 C C   . GLY E 5 64  ? 4.637   -24.958 -50.438 1.00 36.55  ? 64  GLY G C   1 
ATOM   6935 O O   . GLY E 5 64  ? 5.634   -24.650 -51.096 1.00 48.75  ? 64  GLY G O   1 
ATOM   6936 N N   . SER E 5 65  ? 3.476   -24.316 -50.535 1.00 43.44  ? 65  SER G N   1 
ATOM   6937 C CA  . SER E 5 65  ? 3.272   -23.243 -51.497 1.00 39.02  ? 65  SER G CA  1 
ATOM   6938 C C   . SER E 5 65  ? 2.280   -22.241 -50.921 1.00 36.42  ? 65  SER G C   1 
ATOM   6939 O O   . SER E 5 65  ? 1.747   -22.421 -49.822 1.00 41.18  ? 65  SER G O   1 
ATOM   6940 C CB  . SER E 5 65  ? 2.780   -23.793 -52.840 1.00 43.27  ? 65  SER G CB  1 
ATOM   6941 O OG  . SER E 5 65  ? 3.600   -24.857 -53.293 1.00 42.11  ? 65  SER G OG  1 
ATOM   6942 N N   . GLY E 5 66  ? 2.036   -21.175 -51.679 1.00 32.15  ? 66  GLY G N   1 
ATOM   6943 C CA  . GLY E 5 66  ? 1.033   -20.194 -51.330 1.00 26.17  ? 66  GLY G CA  1 
ATOM   6944 C C   . GLY E 5 66  ? 1.567   -19.067 -50.463 1.00 37.96  ? 66  GLY G C   1 
ATOM   6945 O O   . GLY E 5 66  ? 2.664   -19.121 -49.903 1.00 39.99  ? 66  GLY G O   1 
ATOM   6946 N N   . SER E 5 67  ? 0.753   -18.021 -50.359 1.00 29.39  ? 67  SER G N   1 
ATOM   6947 C CA  . SER E 5 67  ? 1.064   -16.851 -49.548 1.00 38.69  ? 67  SER G CA  1 
ATOM   6948 C C   . SER E 5 67  ? -0.246  -16.133 -49.244 1.00 46.78  ? 67  SER G C   1 
ATOM   6949 O O   . SER E 5 67  ? -1.330  -16.606 -49.597 1.00 43.95  ? 67  SER G O   1 
ATOM   6950 C CB  . SER E 5 67  ? 2.065   -15.933 -50.255 1.00 42.36  ? 67  SER G CB  1 
ATOM   6951 O OG  . SER E 5 67  ? 2.384   -14.812 -49.449 1.00 56.69  ? 67  SER G OG  1 
ATOM   6952 N N   . GLY E 5 68  ? -0.139  -14.978 -48.590 1.00 43.52  ? 68  GLY G N   1 
ATOM   6953 C CA  . GLY E 5 68  ? -1.320  -14.223 -48.221 1.00 40.86  ? 68  GLY G CA  1 
ATOM   6954 C C   . GLY E 5 68  ? -2.200  -14.982 -47.251 1.00 48.37  ? 68  GLY G C   1 
ATOM   6955 O O   . GLY E 5 68  ? -1.862  -15.124 -46.072 1.00 51.78  ? 68  GLY G O   1 
ATOM   6956 N N   . THR E 5 69  ? -3.342  -15.472 -47.740 1.00 58.07  ? 69  THR G N   1 
ATOM   6957 C CA  . THR E 5 69  ? -4.235  -16.303 -46.941 1.00 55.28  ? 69  THR G CA  1 
ATOM   6958 C C   . THR E 5 69  ? -4.591  -17.605 -47.655 1.00 43.50  ? 69  THR G C   1 
ATOM   6959 O O   . THR E 5 69  ? -5.561  -18.269 -47.274 1.00 44.28  ? 69  THR G O   1 
ATOM   6960 C CB  . THR E 5 69  ? -5.503  -15.531 -46.565 1.00 53.41  ? 69  THR G CB  1 
ATOM   6961 O OG1 . THR E 5 69  ? -6.497  -16.440 -46.077 1.00 63.55  ? 69  THR G OG1 1 
ATOM   6962 C CG2 . THR E 5 69  ? -6.048  -14.770 -47.764 1.00 56.84  ? 69  THR G CG2 1 
ATOM   6963 N N   . ASP E 5 70  ? -3.826  -17.985 -48.677 1.00 47.05  ? 70  ASP G N   1 
ATOM   6964 C CA  . ASP E 5 70  ? -3.997  -19.248 -49.385 1.00 50.25  ? 70  ASP G CA  1 
ATOM   6965 C C   . ASP E 5 70  ? -2.710  -20.052 -49.276 1.00 45.49  ? 70  ASP G C   1 
ATOM   6966 O O   . ASP E 5 70  ? -1.635  -19.557 -49.632 1.00 53.89  ? 70  ASP G O   1 
ATOM   6967 C CB  . ASP E 5 70  ? -4.348  -19.015 -50.858 1.00 63.23  ? 70  ASP G CB  1 
ATOM   6968 C CG  . ASP E 5 70  ? -5.754  -19.462 -51.204 1.00 63.79  ? 70  ASP G CG  1 
ATOM   6969 O OD1 . ASP E 5 70  ? -6.236  -20.444 -50.601 1.00 69.58  ? 70  ASP G OD1 1 
ATOM   6970 O OD2 . ASP E 5 70  ? -6.380  -18.828 -52.080 1.00 82.96  ? 70  ASP G OD2 1 
ATOM   6971 N N   . PHE E 5 71  ? -2.816  -21.288 -48.790 1.00 38.24  ? 71  PHE G N   1 
ATOM   6972 C CA  . PHE E 5 71  ? -1.643  -22.120 -48.563 1.00 36.98  ? 71  PHE G CA  1 
ATOM   6973 C C   . PHE E 5 71  ? -1.947  -23.560 -48.945 1.00 31.56  ? 71  PHE G C   1 
ATOM   6974 O O   . PHE E 5 71  ? -3.068  -24.044 -48.770 1.00 43.68  ? 71  PHE G O   1 
ATOM   6975 C CB  . PHE E 5 71  ? -1.177  -22.036 -47.105 1.00 32.41  ? 71  PHE G CB  1 
ATOM   6976 C CG  . PHE E 5 71  ? -0.855  -20.640 -46.661 1.00 36.93  ? 71  PHE G CG  1 
ATOM   6977 C CD1 . PHE E 5 71  ? 0.402   -20.103 -46.882 1.00 27.18  ? 71  PHE G CD1 1 
ATOM   6978 C CD2 . PHE E 5 71  ? -1.815  -19.855 -46.041 1.00 25.03  ? 71  PHE G CD2 1 
ATOM   6979 C CE1 . PHE E 5 71  ? 0.700   -18.816 -46.483 1.00 31.89  ? 71  PHE G CE1 1 
ATOM   6980 C CE2 . PHE E 5 71  ? -1.523  -18.568 -45.641 1.00 28.75  ? 71  PHE G CE2 1 
ATOM   6981 C CZ  . PHE E 5 71  ? -0.264  -18.048 -45.864 1.00 31.26  ? 71  PHE G CZ  1 
ATOM   6982 N N   . THR E 5 72  ? -0.928  -24.241 -49.467 1.00 26.72  ? 72  THR G N   1 
ATOM   6983 C CA  . THR E 5 72  ? -1.079  -25.592 -49.986 1.00 33.66  ? 72  THR G CA  1 
ATOM   6984 C C   . THR E 5 72  ? 0.139   -26.428 -49.621 1.00 42.20  ? 72  THR G C   1 
ATOM   6985 O O   . THR E 5 72  ? 1.278   -25.970 -49.750 1.00 45.86  ? 72  THR G O   1 
ATOM   6986 C CB  . THR E 5 72  ? -1.265  -25.583 -51.511 1.00 42.11  ? 72  THR G CB  1 
ATOM   6987 O OG1 . THR E 5 72  ? -2.416  -24.799 -51.850 1.00 45.81  ? 72  THR G OG1 1 
ATOM   6988 C CG2 . THR E 5 72  ? -1.448  -26.997 -52.040 1.00 32.26  ? 72  THR G CG2 1 
ATOM   6989 N N   . LEU E 5 73  ? -0.110  -27.653 -49.166 1.00 29.03  ? 73  LEU G N   1 
ATOM   6990 C CA  . LEU E 5 73  ? 0.936   -28.631 -48.896 1.00 38.91  ? 73  LEU G CA  1 
ATOM   6991 C C   . LEU E 5 73  ? 0.802   -29.766 -49.902 1.00 39.07  ? 73  LEU G C   1 
ATOM   6992 O O   . LEU E 5 73  ? -0.234  -30.439 -49.947 1.00 43.63  ? 73  LEU G O   1 
ATOM   6993 C CB  . LEU E 5 73  ? 0.841   -29.159 -47.464 1.00 38.25  ? 73  LEU G CB  1 
ATOM   6994 C CG  . LEU E 5 73  ? 1.841   -30.245 -47.060 1.00 36.17  ? 73  LEU G CG  1 
ATOM   6995 C CD1 . LEU E 5 73  ? 3.268   -29.718 -47.113 1.00 36.82  ? 73  LEU G CD1 1 
ATOM   6996 C CD2 . LEU E 5 73  ? 1.518   -30.789 -45.676 1.00 39.18  ? 73  LEU G CD2 1 
ATOM   6997 N N   . THR E 5 74  ? 1.844   -29.980 -50.699 1.00 37.94  ? 74  THR G N   1 
ATOM   6998 C CA  . THR E 5 74  ? 1.842   -30.991 -51.747 1.00 49.37  ? 74  THR G CA  1 
ATOM   6999 C C   . THR E 5 74  ? 2.791   -32.119 -51.369 1.00 55.42  ? 74  THR G C   1 
ATOM   7000 O O   . THR E 5 74  ? 3.964   -31.877 -51.067 1.00 58.60  ? 74  THR G O   1 
ATOM   7001 C CB  . THR E 5 74  ? 2.244   -30.389 -53.096 1.00 64.55  ? 74  THR G CB  1 
ATOM   7002 O OG1 . THR E 5 74  ? 1.233   -29.473 -53.532 1.00 57.95  ? 74  THR G OG1 1 
ATOM   7003 C CG2 . THR E 5 74  ? 2.413   -31.485 -54.139 1.00 58.34  ? 74  THR G CG2 1 
ATOM   7004 N N   . ILE E 5 75  ? 2.277   -33.346 -51.389 1.00 52.89  ? 75  ILE G N   1 
ATOM   7005 C CA  . ILE E 5 75  ? 3.026   -34.536 -51.006 1.00 57.60  ? 75  ILE G CA  1 
ATOM   7006 C C   . ILE E 5 75  ? 2.938   -35.514 -52.172 1.00 53.89  ? 75  ILE G C   1 
ATOM   7007 O O   . ILE E 5 75  ? 1.850   -36.009 -52.489 1.00 65.64  ? 75  ILE G O   1 
ATOM   7008 C CB  . ILE E 5 75  ? 2.482   -35.160 -49.714 1.00 52.02  ? 75  ILE G CB  1 
ATOM   7009 C CG1 . ILE E 5 75  ? 2.413   -34.101 -48.610 1.00 49.73  ? 75  ILE G CG1 1 
ATOM   7010 C CG2 . ILE E 5 75  ? 3.352   -36.310 -49.262 1.00 46.42  ? 75  ILE G CG2 1 
ATOM   7011 C CD1 . ILE E 5 75  ? 1.322   -34.344 -47.592 1.00 44.85  ? 75  ILE G CD1 1 
ATOM   7012 N N   . SER E 5 76  ? 4.075   -35.797 -52.802 1.00 56.75  ? 76  SER G N   1 
ATOM   7013 C CA  . SER E 5 76  ? 4.131   -36.576 -54.031 1.00 56.12  ? 76  SER G CA  1 
ATOM   7014 C C   . SER E 5 76  ? 4.810   -37.917 -53.785 1.00 54.62  ? 76  SER G C   1 
ATOM   7015 O O   . SER E 5 76  ? 5.730   -38.022 -52.970 1.00 61.84  ? 76  SER G O   1 
ATOM   7016 C CB  . SER E 5 76  ? 4.884   -35.816 -55.127 1.00 58.17  ? 76  SER G CB  1 
ATOM   7017 O OG  . SER E 5 76  ? 4.389   -34.496 -55.270 1.00 61.10  ? 76  SER G OG  1 
ATOM   7018 N N   . ARG E 5 77  ? 4.355   -38.941 -54.511 1.00 65.29  ? 77  ARG G N   1 
ATOM   7019 C CA  . ARG E 5 77  ? 4.853   -40.308 -54.357 1.00 71.45  ? 77  ARG G CA  1 
ATOM   7020 C C   . ARG E 5 77  ? 4.657   -40.793 -52.919 1.00 71.73  ? 77  ARG G C   1 
ATOM   7021 O O   . ARG E 5 77  ? 5.609   -41.044 -52.176 1.00 74.91  ? 77  ARG G O   1 
ATOM   7022 C CB  . ARG E 5 77  ? 6.320   -40.413 -54.793 1.00 68.86  ? 77  ARG G CB  1 
ATOM   7023 C CG  . ARG E 5 77  ? 6.521   -40.381 -56.300 1.00 75.27  ? 77  ARG G CG  1 
ATOM   7024 C CD  . ARG E 5 77  ? 7.973   -40.119 -56.676 1.00 69.43  ? 77  ARG G CD  1 
ATOM   7025 N NE  . ARG E 5 77  ? 8.349   -38.726 -56.464 1.00 75.67  ? 77  ARG G NE  1 
ATOM   7026 C CZ  . ARG E 5 77  ? 9.042   -38.283 -55.424 1.00 67.28  ? 77  ARG G CZ  1 
ATOM   7027 N NH1 . ARG E 5 77  ? 9.473   -39.104 -54.480 1.00 62.32  ? 77  ARG G NH1 1 
ATOM   7028 N NH2 . ARG E 5 77  ? 9.312   -36.984 -55.330 1.00 53.98  ? 77  ARG G NH2 1 
ATOM   7029 N N   . LEU E 5 78  ? 3.386   -40.914 -52.541 1.00 65.44  ? 78  LEU G N   1 
ATOM   7030 C CA  . LEU E 5 78  ? 3.024   -41.261 -51.173 1.00 57.86  ? 78  LEU G CA  1 
ATOM   7031 C C   . LEU E 5 78  ? 3.531   -42.650 -50.801 1.00 66.84  ? 78  LEU G C   1 
ATOM   7032 O O   . LEU E 5 78  ? 3.709   -43.525 -51.653 1.00 61.22  ? 78  LEU G O   1 
ATOM   7033 C CB  . LEU E 5 78  ? 1.506   -41.200 -50.994 1.00 58.03  ? 78  LEU G CB  1 
ATOM   7034 C CG  . LEU E 5 78  ? 0.858   -39.818 -50.919 1.00 52.53  ? 78  LEU G CG  1 
ATOM   7035 C CD1 . LEU E 5 78  ? -0.641  -39.925 -51.124 1.00 53.08  ? 78  LEU G CD1 1 
ATOM   7036 C CD2 . LEU E 5 78  ? 1.165   -39.168 -49.584 1.00 64.43  ? 78  LEU G CD2 1 
ATOM   7037 N N   . GLU E 5 79  ? 3.763   -42.839 -49.511 1.00 69.52  ? 79  GLU G N   1 
ATOM   7038 C CA  . GLU E 5 79  ? 4.209   -44.092 -48.925 1.00 78.86  ? 79  GLU G CA  1 
ATOM   7039 C C   . GLU E 5 79  ? 3.303   -44.443 -47.756 1.00 78.12  ? 79  GLU G C   1 
ATOM   7040 O O   . GLU E 5 79  ? 2.645   -43.564 -47.187 1.00 75.09  ? 79  GLU G O   1 
ATOM   7041 C CB  . GLU E 5 79  ? 5.672   -43.991 -48.465 1.00 69.10  ? 79  GLU G CB  1 
ATOM   7042 C CG  . GLU E 5 79  ? 6.664   -44.300 -49.575 1.00 77.81  ? 79  GLU G CG  1 
ATOM   7043 C CD  . GLU E 5 79  ? 7.897   -43.422 -49.529 1.00 81.03  ? 79  GLU G CD  1 
ATOM   7044 O OE1 . GLU E 5 79  ? 8.513   -43.307 -48.449 1.00 81.87  ? 79  GLU G OE1 1 
ATOM   7045 O OE2 . GLU E 5 79  ? 8.244   -42.840 -50.578 1.00 77.62  ? 79  GLU G OE2 1 
ATOM   7046 N N   . PRO E 5 80  ? 3.228   -45.726 -47.385 1.00 85.15  ? 80  PRO G N   1 
ATOM   7047 C CA  . PRO E 5 80  ? 2.286   -46.123 -46.323 1.00 87.13  ? 80  PRO G CA  1 
ATOM   7048 C C   . PRO E 5 80  ? 2.528   -45.434 -44.989 1.00 84.46  ? 80  PRO G C   1 
ATOM   7049 O O   . PRO E 5 80  ? 1.587   -45.302 -44.196 1.00 77.47  ? 80  PRO G O   1 
ATOM   7050 C CB  . PRO E 5 80  ? 2.499   -47.640 -46.218 1.00 80.56  ? 80  PRO G CB  1 
ATOM   7051 C CG  . PRO E 5 80  ? 3.024   -48.039 -47.553 1.00 85.68  ? 80  PRO G CG  1 
ATOM   7052 C CD  . PRO E 5 80  ? 3.871   -46.892 -48.015 1.00 83.73  ? 80  PRO G CD  1 
ATOM   7053 N N   . GLU E 5 81  ? 3.753   -44.986 -44.717 1.00 82.16  ? 81  GLU G N   1 
ATOM   7054 C CA  . GLU E 5 81  ? 4.061   -44.332 -43.452 1.00 73.55  ? 81  GLU G CA  1 
ATOM   7055 C C   . GLU E 5 81  ? 3.645   -42.867 -43.420 1.00 66.41  ? 81  GLU G C   1 
ATOM   7056 O O   . GLU E 5 81  ? 3.775   -42.227 -42.371 1.00 64.11  ? 81  GLU G O   1 
ATOM   7057 C CB  . GLU E 5 81  ? 5.557   -44.443 -43.147 1.00 80.59  ? 81  GLU G CB  1 
ATOM   7058 C CG  . GLU E 5 81  ? 6.107   -45.849 -43.267 1.00 89.25  ? 81  GLU G CG  1 
ATOM   7059 C CD  . GLU E 5 81  ? 6.735   -46.113 -44.617 1.00 93.98  ? 81  GLU G CD  1 
ATOM   7060 O OE1 . GLU E 5 81  ? 7.945   -45.845 -44.769 1.00 96.09  ? 81  GLU G OE1 1 
ATOM   7061 O OE2 . GLU E 5 81  ? 6.018   -46.577 -45.528 1.00 94.31  ? 81  GLU G OE2 1 
ATOM   7062 N N   . ASP E 5 82  ? 3.141   -42.325 -44.527 1.00 57.24  ? 82  ASP G N   1 
ATOM   7063 C CA  . ASP E 5 82  ? 2.738   -40.925 -44.576 1.00 56.67  ? 82  ASP G CA  1 
ATOM   7064 C C   . ASP E 5 82  ? 1.361   -40.677 -43.975 1.00 59.00  ? 82  ASP G C   1 
ATOM   7065 O O   . ASP E 5 82  ? 0.905   -39.529 -43.973 1.00 52.13  ? 82  ASP G O   1 
ATOM   7066 C CB  . ASP E 5 82  ? 2.772   -40.416 -46.020 1.00 65.71  ? 82  ASP G CB  1 
ATOM   7067 C CG  . ASP E 5 82  ? 4.185   -40.254 -46.546 1.00 67.97  ? 82  ASP G CG  1 
ATOM   7068 O OD1 . ASP E 5 82  ? 5.140   -40.488 -45.774 1.00 66.00  ? 82  ASP G OD1 1 
ATOM   7069 O OD2 . ASP E 5 82  ? 4.342   -39.892 -47.731 1.00 65.66  ? 82  ASP G OD2 1 
ATOM   7070 N N   . PHE E 5 83  ? 0.688   -41.713 -43.476 1.00 64.27  ? 83  PHE G N   1 
ATOM   7071 C CA  . PHE E 5 83  ? -0.583  -41.527 -42.788 1.00 56.13  ? 83  PHE G CA  1 
ATOM   7072 C C   . PHE E 5 83  ? -0.356  -40.776 -41.483 1.00 51.87  ? 83  PHE G C   1 
ATOM   7073 O O   . PHE E 5 83  ? 0.383   -41.244 -40.609 1.00 46.18  ? 83  PHE G O   1 
ATOM   7074 C CB  . PHE E 5 83  ? -1.253  -42.873 -42.529 1.00 52.90  ? 83  PHE G CB  1 
ATOM   7075 C CG  . PHE E 5 83  ? -2.124  -42.901 -41.296 1.00 57.73  ? 83  PHE G CG  1 
ATOM   7076 C CD1 . PHE E 5 83  ? -1.809  -43.738 -40.238 1.00 60.21  ? 83  PHE G CD1 1 
ATOM   7077 C CD2 . PHE E 5 83  ? -3.248  -42.094 -41.189 1.00 64.13  ? 83  PHE G CD2 1 
ATOM   7078 C CE1 . PHE E 5 83  ? -2.603  -43.775 -39.098 1.00 72.67  ? 83  PHE G CE1 1 
ATOM   7079 C CE2 . PHE E 5 83  ? -4.038  -42.122 -40.057 1.00 67.63  ? 83  PHE G CE2 1 
ATOM   7080 C CZ  . PHE E 5 83  ? -3.716  -42.964 -39.009 1.00 59.88  ? 83  PHE G CZ  1 
ATOM   7081 N N   . ALA E 5 84  ? -0.994  -39.617 -41.354 1.00 31.41  ? 84  ALA G N   1 
ATOM   7082 C CA  . ALA E 5 84  ? -0.891  -38.775 -40.166 1.00 30.33  ? 84  ALA G CA  1 
ATOM   7083 C C   . ALA E 5 84  ? -1.914  -37.654 -40.298 1.00 35.54  ? 84  ALA G C   1 
ATOM   7084 O O   . ALA E 5 84  ? -2.592  -37.520 -41.322 1.00 36.78  ? 84  ALA G O   1 
ATOM   7085 C CB  . ALA E 5 84  ? 0.522   -38.216 -39.989 1.00 33.23  ? 84  ALA G CB  1 
ATOM   7086 N N   . VAL E 5 85  ? -2.023  -36.850 -39.244 1.00 27.98  ? 85  VAL G N   1 
ATOM   7087 C CA  . VAL E 5 85  ? -2.808  -35.622 -39.262 1.00 35.26  ? 85  VAL G CA  1 
ATOM   7088 C C   . VAL E 5 85  ? -1.855  -34.465 -39.522 1.00 41.43  ? 85  VAL G C   1 
ATOM   7089 O O   . VAL E 5 85  ? -0.825  -34.334 -38.847 1.00 39.67  ? 85  VAL G O   1 
ATOM   7090 C CB  . VAL E 5 85  ? -3.575  -35.423 -37.944 1.00 36.96  ? 85  VAL G CB  1 
ATOM   7091 C CG1 . VAL E 5 85  ? -4.380  -34.131 -37.988 1.00 22.43  ? 85  VAL G CG1 1 
ATOM   7092 C CG2 . VAL E 5 85  ? -4.483  -36.612 -37.674 1.00 36.90  ? 85  VAL G CG2 1 
ATOM   7093 N N   . TYR E 5 86  ? -2.185  -33.634 -40.505 1.00 36.81  ? 86  TYR G N   1 
ATOM   7094 C CA  . TYR E 5 86  ? -1.328  -32.534 -40.924 1.00 29.95  ? 86  TYR G CA  1 
ATOM   7095 C C   . TYR E 5 86  ? -1.968  -31.221 -40.494 1.00 35.51  ? 86  TYR G C   1 
ATOM   7096 O O   . TYR E 5 86  ? -3.122  -30.945 -40.839 1.00 35.58  ? 86  TYR G O   1 
ATOM   7097 C CB  . TYR E 5 86  ? -1.102  -32.566 -42.436 1.00 26.80  ? 86  TYR G CB  1 
ATOM   7098 C CG  . TYR E 5 86  ? -0.349  -33.791 -42.909 1.00 28.07  ? 86  TYR G CG  1 
ATOM   7099 C CD1 . TYR E 5 86  ? -1.002  -35.001 -43.104 1.00 25.91  ? 86  TYR G CD1 1 
ATOM   7100 C CD2 . TYR E 5 86  ? 1.016   -33.739 -43.159 1.00 27.37  ? 86  TYR G CD2 1 
ATOM   7101 C CE1 . TYR E 5 86  ? -0.318  -36.123 -43.532 1.00 31.43  ? 86  TYR G CE1 1 
ATOM   7102 C CE2 . TYR E 5 86  ? 1.709   -34.856 -43.589 1.00 24.02  ? 86  TYR G CE2 1 
ATOM   7103 C CZ  . TYR E 5 86  ? 1.036   -36.045 -43.774 1.00 31.01  ? 86  TYR G CZ  1 
ATOM   7104 O OH  . TYR E 5 86  ? 1.720   -37.161 -44.201 1.00 44.69  ? 86  TYR G OH  1 
ATOM   7105 N N   . TYR E 5 87  ? -1.217  -30.417 -39.747 1.00 30.52  ? 87  TYR G N   1 
ATOM   7106 C CA  . TYR E 5 87  ? -1.684  -29.135 -39.243 1.00 30.32  ? 87  TYR G CA  1 
ATOM   7107 C C   . TYR E 5 87  ? -0.940  -27.998 -39.930 1.00 26.35  ? 87  TYR G C   1 
ATOM   7108 O O   . TYR E 5 87  ? 0.236   -28.126 -40.282 1.00 37.78  ? 87  TYR G O   1 
ATOM   7109 C CB  . TYR E 5 87  ? -1.477  -29.021 -37.728 1.00 32.86  ? 87  TYR G CB  1 
ATOM   7110 C CG  . TYR E 5 87  ? -2.231  -30.035 -36.899 1.00 32.82  ? 87  TYR G CG  1 
ATOM   7111 C CD1 . TYR E 5 87  ? -1.661  -31.260 -36.576 1.00 30.60  ? 87  TYR G CD1 1 
ATOM   7112 C CD2 . TYR E 5 87  ? -3.506  -29.759 -36.422 1.00 29.91  ? 87  TYR G CD2 1 
ATOM   7113 C CE1 . TYR E 5 87  ? -2.345  -32.187 -35.811 1.00 30.36  ? 87  TYR G CE1 1 
ATOM   7114 C CE2 . TYR E 5 87  ? -4.197  -30.679 -35.657 1.00 37.23  ? 87  TYR G CE2 1 
ATOM   7115 C CZ  . TYR E 5 87  ? -3.612  -31.891 -35.355 1.00 35.58  ? 87  TYR G CZ  1 
ATOM   7116 O OH  . TYR E 5 87  ? -4.300  -32.808 -34.593 1.00 32.25  ? 87  TYR G OH  1 
ATOM   7117 N N   . CYS E 5 88  ? -1.637  -26.882 -40.120 1.00 25.43  ? 88  CYS G N   1 
ATOM   7118 C CA  . CYS E 5 88  ? -1.013  -25.628 -40.513 1.00 33.36  ? 88  CYS G CA  1 
ATOM   7119 C C   . CYS E 5 88  ? -1.107  -24.644 -39.355 1.00 32.94  ? 88  CYS G C   1 
ATOM   7120 O O   . CYS E 5 88  ? -2.146  -24.543 -38.695 1.00 38.28  ? 88  CYS G O   1 
ATOM   7121 C CB  . CYS E 5 88  ? -1.654  -25.033 -41.776 1.00 35.89  ? 88  CYS G CB  1 
ATOM   7122 S SG  . CYS E 5 88  ? -3.443  -24.727 -41.724 1.00 57.27  ? 88  CYS G SG  1 
ATOM   7123 N N   . GLN E 5 89  ? -0.009  -23.938 -39.101 1.00 29.74  ? 89  GLN G N   1 
ATOM   7124 C CA  . GLN E 5 89  ? 0.077   -22.976 -38.012 1.00 32.44  ? 89  GLN G CA  1 
ATOM   7125 C C   . GLN E 5 89  ? 0.611   -21.658 -38.549 1.00 29.75  ? 89  GLN G C   1 
ATOM   7126 O O   . GLN E 5 89  ? 1.545   -21.640 -39.357 1.00 31.70  ? 89  GLN G O   1 
ATOM   7127 C CB  . GLN E 5 89  ? 0.978   -23.496 -36.881 1.00 34.08  ? 89  GLN G CB  1 
ATOM   7128 C CG  . GLN E 5 89  ? 1.204   -22.509 -35.747 1.00 28.99  ? 89  GLN G CG  1 
ATOM   7129 C CD  . GLN E 5 89  ? 2.637   -22.019 -35.678 1.00 27.45  ? 89  GLN G CD  1 
ATOM   7130 O OE1 . GLN E 5 89  ? 3.568   -22.732 -36.053 1.00 23.82  ? 89  GLN G OE1 1 
ATOM   7131 N NE2 . GLN E 5 89  ? 2.821   -20.794 -35.201 1.00 19.76  ? 89  GLN G NE2 1 
ATOM   7132 N N   . GLN E 5 90  ? 0.014   -20.560 -38.100 1.00 19.62  ? 90  GLN G N   1 
ATOM   7133 C CA  . GLN E 5 90  ? 0.387   -19.226 -38.539 1.00 28.93  ? 90  GLN G CA  1 
ATOM   7134 C C   . GLN E 5 90  ? 1.023   -18.459 -37.388 1.00 37.80  ? 90  GLN G C   1 
ATOM   7135 O O   . GLN E 5 90  ? 0.634   -18.626 -36.227 1.00 31.13  ? 90  GLN G O   1 
ATOM   7136 C CB  . GLN E 5 90  ? -0.830  -18.466 -39.079 1.00 31.83  ? 90  GLN G CB  1 
ATOM   7137 C CG  . GLN E 5 90  ? -1.983  -18.324 -38.093 1.00 32.32  ? 90  GLN G CG  1 
ATOM   7138 C CD  . GLN E 5 90  ? -1.834  -17.116 -37.193 1.00 34.50  ? 90  GLN G CD  1 
ATOM   7139 O OE1 . GLN E 5 90  ? -1.000  -16.246 -37.442 1.00 30.70  ? 90  GLN G OE1 1 
ATOM   7140 N NE2 . GLN E 5 90  ? -2.640  -17.056 -36.139 1.00 35.34  ? 90  GLN G NE2 1 
ATOM   7141 N N   . TYR E 5 91  ? 2.010   -17.625 -37.715 1.00 33.25  ? 91  TYR G N   1 
ATOM   7142 C CA  . TYR E 5 91  ? 2.671   -16.773 -36.734 1.00 35.96  ? 91  TYR G CA  1 
ATOM   7143 C C   . TYR E 5 91  ? 2.714   -15.324 -37.206 1.00 34.54  ? 91  TYR G C   1 
ATOM   7144 O O   . TYR E 5 91  ? 3.623   -14.572 -36.843 1.00 43.18  ? 91  TYR G O   1 
ATOM   7145 C CB  . TYR E 5 91  ? 4.077   -17.283 -36.415 1.00 32.78  ? 91  TYR G CB  1 
ATOM   7146 C CG  . TYR E 5 91  ? 4.853   -17.829 -37.598 1.00 20.35  ? 91  TYR G CG  1 
ATOM   7147 C CD1 . TYR E 5 91  ? 4.702   -19.150 -38.004 1.00 19.50  ? 91  TYR G CD1 1 
ATOM   7148 C CD2 . TYR E 5 91  ? 5.755   -17.032 -38.292 1.00 24.75  ? 91  TYR G CD2 1 
ATOM   7149 C CE1 . TYR E 5 91  ? 5.414   -19.658 -39.075 1.00 22.69  ? 91  TYR G CE1 1 
ATOM   7150 C CE2 . TYR E 5 91  ? 6.475   -17.532 -39.365 1.00 18.82  ? 91  TYR G CE2 1 
ATOM   7151 C CZ  . TYR E 5 91  ? 6.299   -18.845 -39.752 1.00 23.78  ? 91  TYR G CZ  1 
ATOM   7152 O OH  . TYR E 5 91  ? 7.009   -19.348 -40.819 1.00 20.30  ? 91  TYR G OH  1 
ATOM   7153 N N   . GLY E 5 92  ? 1.735   -14.921 -38.018 1.00 36.32  ? 92  GLY G N   1 
ATOM   7154 C CA  . GLY E 5 92  ? 1.689   -13.544 -38.480 1.00 38.92  ? 92  GLY G CA  1 
ATOM   7155 C C   . GLY E 5 92  ? 1.382   -12.558 -37.370 1.00 41.17  ? 92  GLY G C   1 
ATOM   7156 O O   . GLY E 5 92  ? 1.970   -11.474 -37.310 1.00 44.02  ? 92  GLY G O   1 
ATOM   7157 N N   . SER E 5 93  ? 0.458   -12.913 -36.481 1.00 37.83  ? 93  SER G N   1 
ATOM   7158 C CA  . SER E 5 93  ? 0.079   -12.059 -35.366 1.00 43.68  ? 93  SER G CA  1 
ATOM   7159 C C   . SER E 5 93  ? -0.238  -12.931 -34.160 1.00 44.96  ? 93  SER G C   1 
ATOM   7160 O O   . SER E 5 93  ? -0.544  -14.119 -34.288 1.00 45.50  ? 93  SER G O   1 
ATOM   7161 C CB  . SER E 5 93  ? -1.127  -11.173 -35.714 1.00 51.25  ? 93  SER G CB  1 
ATOM   7162 O OG  . SER E 5 93  ? -2.282  -11.956 -35.965 1.00 44.04  ? 93  SER G OG  1 
ATOM   7163 N N   . SER E 5 94  ? -0.159  -12.328 -32.992 1.00 49.77  ? 94  SER G N   1 
ATOM   7164 C CA  . SER E 5 94  ? -0.426  -13.064 -31.768 1.00 47.60  ? 94  SER G CA  1 
ATOM   7165 C C   . SER E 5 94  ? -1.913  -13.023 -31.424 1.00 48.80  ? 94  SER G C   1 
ATOM   7166 O O   . SER E 5 94  ? -2.596  -12.033 -31.707 1.00 55.76  ? 94  SER G O   1 
ATOM   7167 C CB  . SER E 5 94  ? 0.387   -12.484 -30.614 1.00 47.28  ? 94  SER G CB  1 
ATOM   7168 O OG  . SER E 5 94  ? 0.402   -11.068 -30.665 1.00 63.12  ? 94  SER G OG  1 
ATOM   7169 N N   . PRO E 5 95  ? -2.446  -14.090 -30.813 1.00 46.75  ? 95  PRO G N   1 
ATOM   7170 C CA  . PRO E 5 95  ? -1.777  -15.347 -30.448 1.00 34.88  ? 95  PRO G CA  1 
ATOM   7171 C C   . PRO E 5 95  ? -1.617  -16.289 -31.637 1.00 31.75  ? 95  PRO G C   1 
ATOM   7172 O O   . PRO E 5 95  ? -2.416  -16.261 -32.569 1.00 40.70  ? 95  PRO G O   1 
ATOM   7173 C CB  . PRO E 5 95  ? -2.714  -15.927 -29.383 1.00 43.40  ? 95  PRO G CB  1 
ATOM   7174 C CG  . PRO E 5 95  ? -4.075  -15.476 -29.832 1.00 43.77  ? 95  PRO G CG  1 
ATOM   7175 C CD  . PRO E 5 95  ? -3.863  -14.091 -30.404 1.00 46.48  ? 95  PRO G CD  1 
ATOM   7176 N N   . ARG E 5 96  ? -0.588  -17.132 -31.628 1.00 33.05  ? 96  ARG G N   1 
ATOM   7177 C CA  . ARG E 5 96  ? -0.414  -18.106 -32.695 1.00 28.20  ? 96  ARG G CA  1 
ATOM   7178 C C   . ARG E 5 96  ? -1.513  -19.158 -32.632 1.00 32.68  ? 96  ARG G C   1 
ATOM   7179 O O   . ARG E 5 96  ? -1.908  -19.605 -31.552 1.00 42.42  ? 96  ARG G O   1 
ATOM   7180 C CB  . ARG E 5 96  ? 0.960   -18.766 -32.596 1.00 21.83  ? 96  ARG G CB  1 
ATOM   7181 C CG  . ARG E 5 96  ? 2.101   -17.869 -33.047 1.00 34.65  ? 96  ARG G CG  1 
ATOM   7182 C CD  . ARG E 5 96  ? 3.449   -18.542 -32.857 1.00 30.39  ? 96  ARG G CD  1 
ATOM   7183 N NE  . ARG E 5 96  ? 3.856   -18.577 -31.457 1.00 39.54  ? 96  ARG G NE  1 
ATOM   7184 C CZ  . ARG E 5 96  ? 4.930   -19.211 -31.008 1.00 38.93  ? 96  ARG G CZ  1 
ATOM   7185 N NH1 . ARG E 5 96  ? 5.719   -19.894 -31.821 1.00 32.40  ? 96  ARG G NH1 1 
ATOM   7186 N NH2 . ARG E 5 96  ? 5.221   -19.156 -29.711 1.00 31.35  ? 96  ARG G NH2 1 
ATOM   7187 N N   . THR E 5 97  ? -2.009  -19.551 -33.803 1.00 27.63  ? 97  THR G N   1 
ATOM   7188 C CA  . THR E 5 97  ? -3.141  -20.457 -33.904 1.00 30.97  ? 97  THR G CA  1 
ATOM   7189 C C   . THR E 5 97  ? -2.836  -21.566 -34.900 1.00 32.41  ? 97  THR G C   1 
ATOM   7190 O O   . THR E 5 97  ? -2.047  -21.390 -35.832 1.00 37.63  ? 97  THR G O   1 
ATOM   7191 C CB  . THR E 5 97  ? -4.417  -19.720 -34.331 1.00 32.41  ? 97  THR G CB  1 
ATOM   7192 O OG1 . THR E 5 97  ? -4.170  -19.001 -35.546 1.00 40.38  ? 97  THR G OG1 1 
ATOM   7193 C CG2 . THR E 5 97  ? -4.861  -18.745 -33.249 1.00 24.87  ? 97  THR G CG2 1 
ATOM   7194 N N   . PHE E 5 98  ? -3.474  -22.711 -34.687 1.00 30.99  ? 98  PHE G N   1 
ATOM   7195 C CA  . PHE E 5 98  ? -3.337  -23.877 -35.543 1.00 33.91  ? 98  PHE G CA  1 
ATOM   7196 C C   . PHE E 5 98  ? -4.633  -24.129 -36.304 1.00 37.90  ? 98  PHE G C   1 
ATOM   7197 O O   . PHE E 5 98  ? -5.699  -23.606 -35.961 1.00 36.05  ? 98  PHE G O   1 
ATOM   7198 C CB  . PHE E 5 98  ? -2.980  -25.126 -34.729 1.00 27.91  ? 98  PHE G CB  1 
ATOM   7199 C CG  . PHE E 5 98  ? -1.599  -25.099 -34.140 1.00 29.06  ? 98  PHE G CG  1 
ATOM   7200 C CD1 . PHE E 5 98  ? -1.324  -24.343 -33.013 1.00 26.22  ? 98  PHE G CD1 1 
ATOM   7201 C CD2 . PHE E 5 98  ? -0.579  -25.849 -34.703 1.00 34.15  ? 98  PHE G CD2 1 
ATOM   7202 C CE1 . PHE E 5 98  ? -0.056  -24.324 -32.467 1.00 23.34  ? 98  PHE G CE1 1 
ATOM   7203 C CE2 . PHE E 5 98  ? 0.691   -25.836 -34.161 1.00 24.19  ? 98  PHE G CE2 1 
ATOM   7204 C CZ  . PHE E 5 98  ? 0.953   -25.071 -33.041 1.00 30.15  ? 98  PHE G CZ  1 
ATOM   7205 N N   . GLY E 5 99  ? -4.525  -24.941 -37.351 1.00 38.76  ? 99  GLY G N   1 
ATOM   7206 C CA  . GLY E 5 99  ? -5.693  -25.469 -38.015 1.00 43.65  ? 99  GLY G CA  1 
ATOM   7207 C C   . GLY E 5 99  ? -6.235  -26.681 -37.283 1.00 37.95  ? 99  GLY G C   1 
ATOM   7208 O O   . GLY E 5 99  ? -5.657  -27.177 -36.317 1.00 43.87  ? 99  GLY G O   1 
ATOM   7209 N N   . GLN E 5 100 ? -7.380  -27.164 -37.759 1.00 35.54  ? 100 GLN G N   1 
ATOM   7210 C CA  . GLN E 5 100 ? -7.992  -28.333 -37.140 1.00 39.34  ? 100 GLN G CA  1 
ATOM   7211 C C   . GLN E 5 100 ? -7.417  -29.644 -37.657 1.00 37.31  ? 100 GLN G C   1 
ATOM   7212 O O   . GLN E 5 100 ? -7.786  -30.708 -37.148 1.00 35.99  ? 100 GLN G O   1 
ATOM   7213 C CB  . GLN E 5 100 ? -9.508  -28.310 -37.345 1.00 42.17  ? 100 GLN G CB  1 
ATOM   7214 C CG  . GLN E 5 100 ? -10.173 -27.058 -36.796 1.00 54.30  ? 100 GLN G CG  1 
ATOM   7215 C CD  . GLN E 5 100 ? -9.776  -26.768 -35.359 1.00 67.15  ? 100 GLN G CD  1 
ATOM   7216 O OE1 . GLN E 5 100 ? -9.734  -27.667 -34.518 1.00 71.77  ? 100 GLN G OE1 1 
ATOM   7217 N NE2 . GLN E 5 100 ? -9.477  -25.505 -35.073 1.00 57.03  ? 100 GLN G NE2 1 
ATOM   7218 N N   . GLY E 5 101 ? -6.529  -29.593 -38.642 1.00 27.40  ? 101 GLY G N   1 
ATOM   7219 C CA  . GLY E 5 101 ? -5.851  -30.775 -39.126 1.00 36.63  ? 101 GLY G CA  1 
ATOM   7220 C C   . GLY E 5 101 ? -6.557  -31.426 -40.303 1.00 39.28  ? 101 GLY G C   1 
ATOM   7221 O O   . GLY E 5 101 ? -7.727  -31.177 -40.588 1.00 36.91  ? 101 GLY G O   1 
ATOM   7222 N N   . THR E 5 102 ? -5.808  -32.280 -40.998 1.00 36.99  ? 102 THR G N   1 
ATOM   7223 C CA  . THR E 5 102 ? -6.313  -33.041 -42.136 1.00 34.37  ? 102 THR G CA  1 
ATOM   7224 C C   . THR E 5 102 ? -5.877  -34.489 -41.971 1.00 34.51  ? 102 THR G C   1 
ATOM   7225 O O   . THR E 5 102 ? -4.682  -34.795 -42.044 1.00 42.75  ? 102 THR G O   1 
ATOM   7226 C CB  . THR E 5 102 ? -5.806  -32.466 -43.460 1.00 44.40  ? 102 THR G CB  1 
ATOM   7227 O OG1 . THR E 5 102 ? -6.394  -31.177 -43.681 1.00 40.67  ? 102 THR G OG1 1 
ATOM   7228 C CG2 . THR E 5 102 ? -6.164  -33.391 -44.616 1.00 51.21  ? 102 THR G CG2 1 
ATOM   7229 N N   . LYS E 5 103 ? -6.840  -35.377 -41.744 1.00 43.39  ? 103 LYS G N   1 
ATOM   7230 C CA  . LYS E 5 103 ? -6.552  -36.796 -41.588 1.00 42.23  ? 103 LYS G CA  1 
ATOM   7231 C C   . LYS E 5 103 ? -6.306  -37.413 -42.961 1.00 44.16  ? 103 LYS G C   1 
ATOM   7232 O O   . LYS E 5 103 ? -7.174  -37.357 -43.837 1.00 52.36  ? 103 LYS G O   1 
ATOM   7233 C CB  . LYS E 5 103 ? -7.709  -37.492 -40.873 1.00 46.46  ? 103 LYS G CB  1 
ATOM   7234 C CG  . LYS E 5 103 ? -8.196  -36.763 -39.622 1.00 47.29  ? 103 LYS G CG  1 
ATOM   7235 C CD  . LYS E 5 103 ? -9.221  -37.590 -38.856 1.00 62.82  ? 103 LYS G CD  1 
ATOM   7236 C CE  . LYS E 5 103 ? -10.645 -37.143 -39.151 1.00 59.74  ? 103 LYS G CE  1 
ATOM   7237 N NZ  . LYS E 5 103 ? -11.610 -38.273 -39.032 1.00 48.25  ? 103 LYS G NZ  1 
ATOM   7238 N N   . LEU E 5 104 ? -5.127  -38.000 -43.150 1.00 37.03  ? 104 LEU G N   1 
ATOM   7239 C CA  . LEU E 5 104 ? -4.722  -38.573 -44.431 1.00 41.14  ? 104 LEU G CA  1 
ATOM   7240 C C   . LEU E 5 104 ? -4.368  -40.038 -44.211 1.00 42.05  ? 104 LEU G C   1 
ATOM   7241 O O   . LEU E 5 104 ? -3.368  -40.341 -43.556 1.00 53.76  ? 104 LEU G O   1 
ATOM   7242 C CB  . LEU E 5 104 ? -3.540  -37.802 -45.025 1.00 46.79  ? 104 LEU G CB  1 
ATOM   7243 C CG  . LEU E 5 104 ? -3.005  -38.219 -46.400 1.00 48.24  ? 104 LEU G CG  1 
ATOM   7244 C CD1 . LEU E 5 104 ? -1.889  -39.258 -46.290 1.00 48.49  ? 104 LEU G CD1 1 
ATOM   7245 C CD2 . LEU E 5 104 ? -4.144  -38.741 -47.261 1.00 54.17  ? 104 LEU G CD2 1 
ATOM   7246 N N   . GLU E 5 105 ? -5.167  -40.941 -44.774 1.00 47.77  ? 105 GLU G N   1 
ATOM   7247 C CA  . GLU E 5 105 ? -4.910  -42.370 -44.682 1.00 56.99  ? 105 GLU G CA  1 
ATOM   7248 C C   . GLU E 5 105 ? -4.404  -42.906 -46.016 1.00 59.20  ? 105 GLU G C   1 
ATOM   7249 O O   . GLU E 5 105 ? -4.518  -42.256 -47.059 1.00 47.54  ? 105 GLU G O   1 
ATOM   7250 C CB  . GLU E 5 105 ? -6.166  -43.138 -44.251 1.00 57.87  ? 105 GLU G CB  1 
ATOM   7251 C CG  . GLU E 5 105 ? -7.193  -43.341 -45.353 1.00 68.58  ? 105 GLU G CG  1 
ATOM   7252 C CD  . GLU E 5 105 ? -7.977  -44.630 -45.182 1.00 70.43  ? 105 GLU G CD  1 
ATOM   7253 O OE1 . GLU E 5 105 ? -7.377  -45.636 -44.747 1.00 74.04  ? 105 GLU G OE1 1 
ATOM   7254 O OE2 . GLU E 5 105 ? -9.190  -44.638 -45.480 1.00 69.51  ? 105 GLU G OE2 1 
ATOM   7255 N N   . ILE E 5 106 ? -3.845  -44.113 -45.970 1.00 68.84  ? 106 ILE G N   1 
ATOM   7256 C CA  . ILE E 5 106 ? -3.228  -44.753 -47.127 1.00 65.16  ? 106 ILE G CA  1 
ATOM   7257 C C   . ILE E 5 106 ? -4.127  -45.896 -47.578 1.00 64.03  ? 106 ILE G C   1 
ATOM   7258 O O   . ILE E 5 106 ? -4.445  -46.796 -46.790 1.00 68.19  ? 106 ILE G O   1 
ATOM   7259 C CB  . ILE E 5 106 ? -1.812  -45.258 -46.807 1.00 77.91  ? 106 ILE G CB  1 
ATOM   7260 C CG1 . ILE E 5 106 ? -0.859  -44.079 -46.591 1.00 68.18  ? 106 ILE G CG1 1 
ATOM   7261 C CG2 . ILE E 5 106 ? -1.301  -46.166 -47.916 1.00 79.46  ? 106 ILE G CG2 1 
ATOM   7262 C CD1 . ILE E 5 106 ? -0.605  -43.258 -47.836 1.00 68.82  ? 106 ILE G CD1 1 
ATOM   7263 N N   . LYS E 5 107 ? -4.533  -45.863 -48.845 1.00 68.83  ? 107 LYS G N   1 
ATOM   7264 C CA  . LYS E 5 107 ? -5.393  -46.896 -49.398 1.00 67.17  ? 107 LYS G CA  1 
ATOM   7265 C C   . LYS E 5 107 ? -4.596  -48.162 -49.706 1.00 66.89  ? 107 LYS G C   1 
ATOM   7266 O O   . LYS E 5 107 ? -3.363  -48.161 -49.753 1.00 62.78  ? 107 LYS G O   1 
ATOM   7267 C CB  . LYS E 5 107 ? -6.090  -46.397 -50.664 1.00 56.36  ? 107 LYS G CB  1 
ATOM   7268 C CG  . LYS E 5 107 ? -7.138  -45.323 -50.428 1.00 66.85  ? 107 LYS G CG  1 
ATOM   7269 C CD  . LYS E 5 107 ? -7.961  -45.056 -51.686 1.00 70.44  ? 107 LYS G CD  1 
ATOM   7270 C CE  . LYS E 5 107 ? -9.254  -44.318 -51.345 1.00 67.80  ? 107 LYS G CE  1 
ATOM   7271 N NZ  . LYS E 5 107 ? -9.688  -43.360 -52.404 1.00 61.50  ? 107 LYS G NZ  1 
ATOM   7272 N N   . ARG E 5 108 ? -5.325  -49.254 -49.921 1.00 61.63  ? 108 ARG G N   1 
ATOM   7273 C CA  . ARG E 5 108 ? -4.731  -50.536 -50.278 1.00 66.21  ? 108 ARG G CA  1 
ATOM   7274 C C   . ARG E 5 108 ? -5.824  -51.421 -50.864 1.00 67.08  ? 108 ARG G C   1 
ATOM   7275 O O   . ARG E 5 108 ? -6.979  -51.008 -51.002 1.00 68.01  ? 108 ARG G O   1 
ATOM   7276 C CB  . ARG E 5 108 ? -4.070  -51.206 -49.070 1.00 66.66  ? 108 ARG G CB  1 
ATOM   7277 C CG  . ARG E 5 108 ? -5.047  -51.624 -47.982 1.00 64.08  ? 108 ARG G CG  1 
ATOM   7278 C CD  . ARG E 5 108 ? -4.529  -52.830 -47.219 1.00 55.09  ? 108 ARG G CD  1 
ATOM   7279 N NE  . ARG E 5 108 ? -4.461  -54.016 -48.065 1.00 45.59  ? 108 ARG G NE  1 
ATOM   7280 C CZ  . ARG E 5 108 ? -3.892  -55.160 -47.711 1.00 63.48  ? 108 ARG G CZ  1 
ATOM   7281 N NH1 . ARG E 5 108 ? -3.310  -55.307 -46.532 1.00 56.22  ? 108 ARG G NH1 1 
ATOM   7282 N NH2 . ARG E 5 108 ? -3.905  -56.182 -48.562 1.00 73.31  ? 108 ARG G NH2 1 
ATOM   7283 N N   . THR E 5 109 ? -5.447  -52.649 -51.212 1.00 68.45  ? 109 THR G N   1 
ATOM   7284 C CA  . THR E 5 109 ? -6.422  -53.623 -51.678 1.00 71.12  ? 109 THR G CA  1 
ATOM   7285 C C   . THR E 5 109 ? -7.357  -54.019 -50.540 1.00 73.39  ? 109 THR G C   1 
ATOM   7286 O O   . THR E 5 109 ? -6.966  -54.061 -49.370 1.00 71.06  ? 109 THR G O   1 
ATOM   7287 C CB  . THR E 5 109 ? -5.723  -54.865 -52.232 1.00 63.95  ? 109 THR G CB  1 
ATOM   7288 O OG1 . THR E 5 109 ? -5.229  -55.662 -51.148 1.00 69.80  ? 109 THR G OG1 1 
ATOM   7289 C CG2 . THR E 5 109 ? -4.560  -54.464 -53.128 1.00 55.91  ? 109 THR G CG2 1 
ATOM   7290 N N   . VAL E 5 110 ? -8.609  -54.306 -50.896 1.00 69.93  ? 110 VAL G N   1 
ATOM   7291 C CA  . VAL E 5 110 ? -9.610  -54.662 -49.898 1.00 62.37  ? 110 VAL G CA  1 
ATOM   7292 C C   . VAL E 5 110 ? -9.248  -56.002 -49.272 1.00 69.13  ? 110 VAL G C   1 
ATOM   7293 O O   . VAL E 5 110 ? -8.967  -56.980 -49.976 1.00 65.71  ? 110 VAL G O   1 
ATOM   7294 C CB  . VAL E 5 110 ? -11.008 -54.696 -50.532 1.00 58.67  ? 110 VAL G CB  1 
ATOM   7295 C CG1 . VAL E 5 110 ? -12.041 -55.164 -49.520 1.00 57.82  ? 110 VAL G CG1 1 
ATOM   7296 C CG2 . VAL E 5 110 ? -11.373 -53.322 -51.075 1.00 45.99  ? 110 VAL G CG2 1 
ATOM   7297 N N   . ALA E 5 111 ? -9.253  -56.051 -47.941 1.00 72.30  ? 111 ALA G N   1 
ATOM   7298 C CA  . ALA E 5 111 ? -8.876  -57.238 -47.188 1.00 64.88  ? 111 ALA G CA  1 
ATOM   7299 C C   . ALA E 5 111 ? -10.035 -57.693 -46.313 1.00 59.74  ? 111 ALA G C   1 
ATOM   7300 O O   . ALA E 5 111 ? -10.700 -56.874 -45.669 1.00 63.06  ? 111 ALA G O   1 
ATOM   7301 C CB  . ALA E 5 111 ? -7.640  -56.975 -46.321 1.00 59.93  ? 111 ALA G CB  1 
ATOM   7302 N N   . ALA E 5 112 ? -10.271 -59.000 -46.294 1.00 55.23  ? 112 ALA G N   1 
ATOM   7303 C CA  . ALA E 5 112 ? -11.359 -59.572 -45.508 1.00 59.87  ? 112 ALA G CA  1 
ATOM   7304 C C   . ALA E 5 112 ? -10.948 -59.693 -44.044 1.00 66.92  ? 112 ALA G C   1 
ATOM   7305 O O   . ALA E 5 112 ? -9.876  -60.231 -43.751 1.00 65.52  ? 112 ALA G O   1 
ATOM   7306 C CB  . ALA E 5 112 ? -11.755 -60.941 -46.054 1.00 55.58  ? 112 ALA G CB  1 
ATOM   7307 N N   . PRO E 5 113 ? -11.758 -59.200 -43.110 1.00 58.95  ? 113 PRO G N   1 
ATOM   7308 C CA  . PRO E 5 113 ? -11.436 -59.368 -41.690 1.00 56.74  ? 113 PRO G CA  1 
ATOM   7309 C C   . PRO E 5 113 ? -11.498 -60.825 -41.260 1.00 60.80  ? 113 PRO G C   1 
ATOM   7310 O O   . PRO E 5 113 ? -12.288 -61.621 -41.774 1.00 64.39  ? 113 PRO G O   1 
ATOM   7311 C CB  . PRO E 5 113 ? -12.513 -58.540 -40.979 1.00 48.76  ? 113 PRO G CB  1 
ATOM   7312 C CG  . PRO E 5 113 ? -13.639 -58.466 -41.956 1.00 57.22  ? 113 PRO G CG  1 
ATOM   7313 C CD  . PRO E 5 113 ? -13.003 -58.441 -43.313 1.00 56.91  ? 113 PRO G CD  1 
ATOM   7314 N N   . SER E 5 114 ? -10.646 -61.166 -40.297 1.00 51.91  ? 114 SER G N   1 
ATOM   7315 C CA  . SER E 5 114 ? -10.664 -62.473 -39.652 1.00 59.16  ? 114 SER G CA  1 
ATOM   7316 C C   . SER E 5 114 ? -11.415 -62.313 -38.335 1.00 56.68  ? 114 SER G C   1 
ATOM   7317 O O   . SER E 5 114 ? -10.958 -61.599 -37.435 1.00 57.41  ? 114 SER G O   1 
ATOM   7318 C CB  . SER E 5 114 ? -9.245  -62.993 -39.432 1.00 67.50  ? 114 SER G CB  1 
ATOM   7319 O OG  . SER E 5 114 ? -8.530  -63.051 -40.657 1.00 59.56  ? 114 SER G OG  1 
ATOM   7320 N N   . VAL E 5 115 ? -12.565 -62.973 -38.220 1.00 51.99  ? 115 VAL G N   1 
ATOM   7321 C CA  . VAL E 5 115 ? -13.496 -62.743 -37.121 1.00 43.25  ? 115 VAL G CA  1 
ATOM   7322 C C   . VAL E 5 115 ? -13.260 -63.785 -36.037 1.00 51.07  ? 115 VAL G C   1 
ATOM   7323 O O   . VAL E 5 115 ? -13.240 -64.991 -36.313 1.00 58.66  ? 115 VAL G O   1 
ATOM   7324 C CB  . VAL E 5 115 ? -14.954 -62.778 -37.609 1.00 50.52  ? 115 VAL G CB  1 
ATOM   7325 C CG1 . VAL E 5 115 ? -15.899 -62.400 -36.477 1.00 49.83  ? 115 VAL G CG1 1 
ATOM   7326 C CG2 . VAL E 5 115 ? -15.138 -61.846 -38.797 1.00 55.44  ? 115 VAL G CG2 1 
ATOM   7327 N N   . PHE E 5 116 ? -13.078 -63.316 -34.803 1.00 49.65  ? 116 PHE G N   1 
ATOM   7328 C CA  . PHE E 5 116 ? -12.954 -64.173 -33.635 1.00 51.90  ? 116 PHE G CA  1 
ATOM   7329 C C   . PHE E 5 116 ? -13.850 -63.634 -32.530 1.00 49.35  ? 116 PHE G C   1 
ATOM   7330 O O   . PHE E 5 116 ? -14.024 -62.420 -32.390 1.00 49.56  ? 116 PHE G O   1 
ATOM   7331 C CB  . PHE E 5 116 ? -11.502 -64.252 -33.135 1.00 64.65  ? 116 PHE G CB  1 
ATOM   7332 C CG  . PHE E 5 116 ? -10.517 -64.682 -34.185 1.00 67.29  ? 116 PHE G CG  1 
ATOM   7333 C CD1 . PHE E 5 116 ? -9.898  -63.746 -34.998 1.00 53.06  ? 116 PHE G CD1 1 
ATOM   7334 C CD2 . PHE E 5 116 ? -10.204 -66.021 -34.356 1.00 65.05  ? 116 PHE G CD2 1 
ATOM   7335 C CE1 . PHE E 5 116 ? -8.991  -64.136 -35.965 1.00 54.05  ? 116 PHE G CE1 1 
ATOM   7336 C CE2 . PHE E 5 116 ? -9.297  -66.418 -35.322 1.00 73.67  ? 116 PHE G CE2 1 
ATOM   7337 C CZ  . PHE E 5 116 ? -8.690  -65.474 -36.127 1.00 68.15  ? 116 PHE G CZ  1 
ATOM   7338 N N   . ILE E 5 117 ? -14.422 -64.545 -31.746 1.00 41.74  ? 117 ILE G N   1 
ATOM   7339 C CA  . ILE E 5 117 ? -15.308 -64.186 -30.645 1.00 47.18  ? 117 ILE G CA  1 
ATOM   7340 C C   . ILE E 5 117 ? -14.804 -64.862 -29.376 1.00 48.19  ? 117 ILE G C   1 
ATOM   7341 O O   . ILE E 5 117 ? -14.475 -66.053 -29.388 1.00 44.89  ? 117 ILE G O   1 
ATOM   7342 C CB  . ILE E 5 117 ? -16.775 -64.569 -30.936 1.00 43.08  ? 117 ILE G CB  1 
ATOM   7343 C CG1 . ILE E 5 117 ? -17.673 -64.213 -29.747 1.00 38.40  ? 117 ILE G CG1 1 
ATOM   7344 C CG2 . ILE E 5 117 ? -16.898 -66.043 -31.307 1.00 32.05  ? 117 ILE G CG2 1 
ATOM   7345 C CD1 . ILE E 5 117 ? -19.153 -64.312 -30.054 1.00 32.29  ? 117 ILE G CD1 1 
ATOM   7346 N N   . PHE E 5 118 ? -14.722 -64.095 -28.291 1.00 51.14  ? 118 PHE G N   1 
ATOM   7347 C CA  . PHE E 5 118 ? -14.184 -64.586 -27.031 1.00 46.37  ? 118 PHE G CA  1 
ATOM   7348 C C   . PHE E 5 118 ? -15.268 -64.601 -25.966 1.00 48.16  ? 118 PHE G C   1 
ATOM   7349 O O   . PHE E 5 118 ? -15.797 -63.535 -25.615 1.00 42.45  ? 118 PHE G O   1 
ATOM   7350 C CB  . PHE E 5 118 ? -13.008 -63.721 -26.572 1.00 47.99  ? 118 PHE G CB  1 
ATOM   7351 C CG  . PHE E 5 118 ? -11.883 -63.649 -27.564 1.00 52.72  ? 118 PHE G CG  1 
ATOM   7352 C CD1 . PHE E 5 118 ? -11.054 -64.739 -27.774 1.00 63.04  ? 118 PHE G CD1 1 
ATOM   7353 C CD2 . PHE E 5 118 ? -11.644 -62.485 -28.275 1.00 42.45  ? 118 PHE G CD2 1 
ATOM   7354 C CE1 . PHE E 5 118 ? -10.016 -64.672 -28.682 1.00 69.89  ? 118 PHE G CE1 1 
ATOM   7355 C CE2 . PHE E 5 118 ? -10.607 -62.412 -29.184 1.00 53.19  ? 118 PHE G CE2 1 
ATOM   7356 C CZ  . PHE E 5 118 ? -9.792  -63.507 -29.388 1.00 55.86  ? 118 PHE G CZ  1 
ATOM   7357 N N   . PRO E 5 119 ? -15.632 -65.762 -25.432 1.00 50.39  ? 119 PRO G N   1 
ATOM   7358 C CA  . PRO E 5 119 ? -16.547 -65.802 -24.287 1.00 45.35  ? 119 PRO G CA  1 
ATOM   7359 C C   . PRO E 5 119 ? -15.890 -65.210 -23.053 1.00 48.89  ? 119 PRO G C   1 
ATOM   7360 O O   . PRO E 5 119 ? -14.654 -65.192 -22.948 1.00 58.81  ? 119 PRO G O   1 
ATOM   7361 C CB  . PRO E 5 119 ? -16.824 -67.303 -24.109 1.00 42.12  ? 119 PRO G CB  1 
ATOM   7362 C CG  . PRO E 5 119 ? -15.650 -67.980 -24.731 1.00 44.45  ? 119 PRO G CG  1 
ATOM   7363 C CD  . PRO E 5 119 ? -15.244 -67.109 -25.884 1.00 38.90  ? 119 PRO G CD  1 
ATOM   7364 N N   . PRO E 5 120 ? -16.677 -64.705 -22.105 1.00 40.60  ? 120 PRO G N   1 
ATOM   7365 C CA  . PRO E 5 120 ? -16.086 -64.100 -20.906 1.00 42.87  ? 120 PRO G CA  1 
ATOM   7366 C C   . PRO E 5 120 ? -15.337 -65.121 -20.063 1.00 49.11  ? 120 PRO G C   1 
ATOM   7367 O O   . PRO E 5 120 ? -15.678 -66.306 -20.024 1.00 44.68  ? 120 PRO G O   1 
ATOM   7368 C CB  . PRO E 5 120 ? -17.300 -63.543 -20.154 1.00 42.47  ? 120 PRO G CB  1 
ATOM   7369 C CG  . PRO E 5 120 ? -18.442 -64.378 -20.622 1.00 39.75  ? 120 PRO G CG  1 
ATOM   7370 C CD  . PRO E 5 120 ? -18.149 -64.692 -22.061 1.00 42.79  ? 120 PRO G CD  1 
ATOM   7371 N N   . SER E 5 121 ? -14.300 -64.639 -19.384 1.00 55.16  ? 121 SER G N   1 
ATOM   7372 C CA  . SER E 5 121 ? -13.480 -65.502 -18.548 1.00 55.34  ? 121 SER G CA  1 
ATOM   7373 C C   . SER E 5 121 ? -14.230 -65.902 -17.282 1.00 51.35  ? 121 SER G C   1 
ATOM   7374 O O   . SER E 5 121 ? -15.139 -65.206 -16.821 1.00 49.93  ? 121 SER G O   1 
ATOM   7375 C CB  . SER E 5 121 ? -12.172 -64.801 -18.181 1.00 50.54  ? 121 SER G CB  1 
ATOM   7376 O OG  . SER E 5 121 ? -12.417 -63.625 -17.431 1.00 63.94  ? 121 SER G OG  1 
ATOM   7377 N N   . ASP E 5 122 ? -13.837 -67.047 -16.719 1.00 55.52  ? 122 ASP G N   1 
ATOM   7378 C CA  . ASP E 5 122 ? -14.487 -67.535 -15.506 1.00 59.46  ? 122 ASP G CA  1 
ATOM   7379 C C   . ASP E 5 122 ? -14.164 -66.653 -14.306 1.00 60.52  ? 122 ASP G C   1 
ATOM   7380 O O   . ASP E 5 122 ? -15.014 -66.457 -13.429 1.00 57.82  ? 122 ASP G O   1 
ATOM   7381 C CB  . ASP E 5 122 ? -14.080 -68.983 -15.234 1.00 63.09  ? 122 ASP G CB  1 
ATOM   7382 C CG  . ASP E 5 122 ? -14.691 -69.954 -16.225 1.00 75.76  ? 122 ASP G CG  1 
ATOM   7383 O OD1 . ASP E 5 122 ? -14.063 -70.214 -17.272 1.00 75.93  ? 122 ASP G OD1 1 
ATOM   7384 O OD2 . ASP E 5 122 ? -15.806 -70.451 -15.959 1.00 73.21  ? 122 ASP G OD2 1 
ATOM   7385 N N   . GLU E 5 123 ? -12.939 -66.122 -14.240 1.00 49.64  ? 123 GLU G N   1 
ATOM   7386 C CA  . GLU E 5 123 ? -12.584 -65.237 -13.135 1.00 64.04  ? 123 GLU G CA  1 
ATOM   7387 C C   . GLU E 5 123 ? -13.427 -63.969 -13.153 1.00 60.75  ? 123 GLU G C   1 
ATOM   7388 O O   . GLU E 5 123 ? -13.840 -63.475 -12.097 1.00 64.16  ? 123 GLU G O   1 
ATOM   7389 C CB  . GLU E 5 123 ? -11.093 -64.896 -13.177 1.00 58.03  ? 123 GLU G CB  1 
ATOM   7390 C CG  . GLU E 5 123 ? -10.500 -64.762 -14.568 1.00 61.70  ? 123 GLU G CG  1 
ATOM   7391 C CD  . GLU E 5 123 ? -9.745  -66.005 -14.998 1.00 78.59  ? 123 GLU G CD  1 
ATOM   7392 O OE1 . GLU E 5 123 ? -10.399 -66.995 -15.388 1.00 67.55  ? 123 GLU G OE1 1 
ATOM   7393 O OE2 . GLU E 5 123 ? -8.497  -65.994 -14.932 1.00 82.39  ? 123 GLU G OE2 1 
ATOM   7394 N N   . GLN E 5 124 ? -13.688 -63.423 -14.343 1.00 62.32  ? 124 GLN G N   1 
ATOM   7395 C CA  . GLN E 5 124 ? -14.583 -62.276 -14.442 1.00 50.27  ? 124 GLN G CA  1 
ATOM   7396 C C   . GLN E 5 124 ? -15.999 -62.647 -14.021 1.00 51.72  ? 124 GLN G C   1 
ATOM   7397 O O   . GLN E 5 124 ? -16.677 -61.866 -13.344 1.00 50.86  ? 124 GLN G O   1 
ATOM   7398 C CB  . GLN E 5 124 ? -14.579 -61.717 -15.864 1.00 50.56  ? 124 GLN G CB  1 
ATOM   7399 C CG  . GLN E 5 124 ? -15.421 -60.459 -16.026 1.00 44.29  ? 124 GLN G CG  1 
ATOM   7400 C CD  . GLN E 5 124 ? -15.525 -60.003 -17.468 1.00 40.63  ? 124 GLN G CD  1 
ATOM   7401 O OE1 . GLN E 5 124 ? -15.175 -60.737 -18.391 1.00 47.07  ? 124 GLN G OE1 1 
ATOM   7402 N NE2 . GLN E 5 124 ? -16.009 -58.782 -17.667 1.00 35.28  ? 124 GLN G NE2 1 
ATOM   7403 N N   . LEU E 5 125 ? -16.459 -63.842 -14.407 1.00 54.67  ? 125 LEU G N   1 
ATOM   7404 C CA  . LEU E 5 125 ? -17.825 -64.257 -14.108 1.00 51.01  ? 125 LEU G CA  1 
ATOM   7405 C C   . LEU E 5 125 ? -18.093 -64.359 -12.612 1.00 57.25  ? 125 LEU G C   1 
ATOM   7406 O O   . LEU E 5 125 ? -19.253 -64.261 -12.196 1.00 59.16  ? 125 LEU G O   1 
ATOM   7407 C CB  . LEU E 5 125 ? -18.132 -65.594 -14.784 1.00 54.19  ? 125 LEU G CB  1 
ATOM   7408 C CG  . LEU E 5 125 ? -18.384 -65.536 -16.292 1.00 52.20  ? 125 LEU G CG  1 
ATOM   7409 C CD1 . LEU E 5 125 ? -18.696 -66.920 -16.842 1.00 51.96  ? 125 LEU G CD1 1 
ATOM   7410 C CD2 . LEU E 5 125 ? -19.511 -64.564 -16.606 1.00 43.30  ? 125 LEU G CD2 1 
ATOM   7411 N N   . LYS E 5 126 ? -17.057 -64.549 -11.794 1.00 62.88  ? 126 LYS G N   1 
ATOM   7412 C CA  . LYS E 5 126 ? -17.244 -64.577 -10.350 1.00 62.49  ? 126 LYS G CA  1 
ATOM   7413 C C   . LYS E 5 126 ? -17.437 -63.190 -9.750  1.00 61.07  ? 126 LYS G C   1 
ATOM   7414 O O   . LYS E 5 126 ? -17.837 -63.088 -8.585  1.00 63.11  ? 126 LYS G O   1 
ATOM   7415 C CB  . LYS E 5 126 ? -16.055 -65.260 -9.669  1.00 68.62  ? 126 LYS G CB  1 
ATOM   7416 C CG  . LYS E 5 126 ? -15.792 -66.689 -10.122 1.00 65.89  ? 126 LYS G CG  1 
ATOM   7417 C CD  . LYS E 5 126 ? -15.240 -67.524 -8.974  1.00 64.70  ? 126 LYS G CD  1 
ATOM   7418 C CE  . LYS E 5 126 ? -14.192 -68.520 -9.449  1.00 67.05  ? 126 LYS G CE  1 
ATOM   7419 N NZ  . LYS E 5 126 ? -14.706 -69.432 -10.507 1.00 59.56  ? 126 LYS G NZ  1 
ATOM   7420 N N   . SER E 5 127 ? -17.166 -62.127 -10.508 1.00 58.74  ? 127 SER G N   1 
ATOM   7421 C CA  . SER E 5 127 ? -17.244 -60.768 -9.988  1.00 59.83  ? 127 SER G CA  1 
ATOM   7422 C C   . SER E 5 127 ? -18.595 -60.101 -10.220 1.00 71.00  ? 127 SER G C   1 
ATOM   7423 O O   . SER E 5 127 ? -18.819 -59.002 -9.700  1.00 80.57  ? 127 SER G O   1 
ATOM   7424 C CB  . SER E 5 127 ? -16.138 -59.906 -10.609 1.00 53.29  ? 127 SER G CB  1 
ATOM   7425 O OG  . SER E 5 127 ? -16.204 -59.930 -12.024 1.00 68.40  ? 127 SER G OG  1 
ATOM   7426 N N   . GLY E 5 128 ? -19.497 -60.726 -10.976 1.00 58.29  ? 128 GLY G N   1 
ATOM   7427 C CA  . GLY E 5 128 ? -20.818 -60.178 -11.209 1.00 57.87  ? 128 GLY G CA  1 
ATOM   7428 C C   . GLY E 5 128 ? -21.020 -59.485 -12.541 1.00 55.64  ? 128 GLY G C   1 
ATOM   7429 O O   . GLY E 5 128 ? -22.112 -58.954 -12.779 1.00 54.16  ? 128 GLY G O   1 
ATOM   7430 N N   . THR E 5 129 ? -20.014 -59.468 -13.414 1.00 52.69  ? 129 THR G N   1 
ATOM   7431 C CA  . THR E 5 129 ? -20.137 -58.853 -14.729 1.00 47.86  ? 129 THR G CA  1 
ATOM   7432 C C   . THR E 5 129 ? -19.524 -59.769 -15.779 1.00 48.85  ? 129 THR G C   1 
ATOM   7433 O O   . THR E 5 129 ? -18.627 -60.563 -15.486 1.00 44.58  ? 129 THR G O   1 
ATOM   7434 C CB  . THR E 5 129 ? -19.461 -57.475 -14.787 1.00 49.10  ? 129 THR G CB  1 
ATOM   7435 O OG1 . THR E 5 129 ? -18.156 -57.552 -14.199 1.00 66.75  ? 129 THR G OG1 1 
ATOM   7436 C CG2 . THR E 5 129 ? -20.292 -56.435 -14.048 1.00 45.52  ? 129 THR G CG2 1 
ATOM   7437 N N   . ALA E 5 130 ? -20.018 -59.648 -17.009 1.00 35.77  ? 130 ALA G N   1 
ATOM   7438 C CA  . ALA E 5 130 ? -19.546 -60.449 -18.129 1.00 33.03  ? 130 ALA G CA  1 
ATOM   7439 C C   . ALA E 5 130 ? -19.254 -59.549 -19.319 1.00 41.98  ? 130 ALA G C   1 
ATOM   7440 O O   . ALA E 5 130 ? -20.003 -58.608 -19.597 1.00 40.60  ? 130 ALA G O   1 
ATOM   7441 C CB  . ALA E 5 130 ? -20.570 -61.519 -18.522 1.00 28.03  ? 130 ALA G CB  1 
ATOM   7442 N N   . SER E 5 131 ? -18.160 -59.843 -20.020 1.00 27.75  ? 131 SER G N   1 
ATOM   7443 C CA  . SER E 5 131 ? -17.768 -59.104 -21.213 1.00 27.95  ? 131 SER G CA  1 
ATOM   7444 C C   . SER E 5 131 ? -17.512 -60.085 -22.346 1.00 36.07  ? 131 SER G C   1 
ATOM   7445 O O   . SER E 5 131 ? -16.743 -61.038 -22.183 1.00 40.15  ? 131 SER G O   1 
ATOM   7446 C CB  . SER E 5 131 ? -16.521 -58.251 -20.956 1.00 27.63  ? 131 SER G CB  1 
ATOM   7447 O OG  . SER E 5 131 ? -16.753 -57.298 -19.934 1.00 37.96  ? 131 SER G OG  1 
ATOM   7448 N N   . VAL E 5 132 ? -18.151 -59.849 -23.489 1.00 30.06  ? 132 VAL G N   1 
ATOM   7449 C CA  . VAL E 5 132 ? -17.988 -60.673 -24.680 1.00 31.29  ? 132 VAL G CA  1 
ATOM   7450 C C   . VAL E 5 132 ? -17.335 -59.819 -25.757 1.00 34.86  ? 132 VAL G C   1 
ATOM   7451 O O   . VAL E 5 132 ? -17.821 -58.726 -26.071 1.00 36.80  ? 132 VAL G O   1 
ATOM   7452 C CB  . VAL E 5 132 ? -19.332 -61.243 -25.165 1.00 33.42  ? 132 VAL G CB  1 
ATOM   7453 C CG1 . VAL E 5 132 ? -19.106 -62.276 -26.257 1.00 22.42  ? 132 VAL G CG1 1 
ATOM   7454 C CG2 . VAL E 5 132 ? -20.103 -61.847 -24.001 1.00 27.97  ? 132 VAL G CG2 1 
ATOM   7455 N N   . VAL E 5 133 ? -16.239 -60.318 -26.324 1.00 37.25  ? 133 VAL G N   1 
ATOM   7456 C CA  . VAL E 5 133 ? -15.407 -59.557 -27.248 1.00 38.95  ? 133 VAL G CA  1 
ATOM   7457 C C   . VAL E 5 133 ? -15.463 -60.214 -28.620 1.00 36.55  ? 133 VAL G C   1 
ATOM   7458 O O   . VAL E 5 133 ? -15.283 -61.431 -28.740 1.00 47.35  ? 133 VAL G O   1 
ATOM   7459 C CB  . VAL E 5 133 ? -13.953 -59.461 -26.751 1.00 33.94  ? 133 VAL G CB  1 
ATOM   7460 C CG1 . VAL E 5 133 ? -13.110 -58.652 -27.725 1.00 43.82  ? 133 VAL G CG1 1 
ATOM   7461 C CG2 . VAL E 5 133 ? -13.908 -58.849 -25.361 1.00 27.88  ? 133 VAL G CG2 1 
ATOM   7462 N N   . CYS E 5 134 ? -15.716 -59.407 -29.646 1.00 35.80  ? 134 CYS G N   1 
ATOM   7463 C CA  . CYS E 5 134 ? -15.659 -59.839 -31.035 1.00 37.43  ? 134 CYS G CA  1 
ATOM   7464 C C   . CYS E 5 134 ? -14.523 -59.097 -31.726 1.00 48.51  ? 134 CYS G C   1 
ATOM   7465 O O   . CYS E 5 134 ? -14.421 -57.870 -31.616 1.00 43.21  ? 134 CYS G O   1 
ATOM   7466 C CB  . CYS E 5 134 ? -16.987 -59.576 -31.748 1.00 36.70  ? 134 CYS G CB  1 
ATOM   7467 S SG  . CYS E 5 134 ? -17.094 -60.257 -33.418 1.00 48.28  ? 134 CYS G SG  1 
ATOM   7468 N N   . LEU E 5 135 ? -13.670 -59.838 -32.428 1.00 51.98  ? 135 LEU G N   1 
ATOM   7469 C CA  . LEU E 5 135 ? -12.445 -59.298 -33.002 1.00 50.79  ? 135 LEU G CA  1 
ATOM   7470 C C   . LEU E 5 135 ? -12.529 -59.289 -34.522 1.00 48.24  ? 135 LEU G C   1 
ATOM   7471 O O   . LEU E 5 135 ? -12.842 -60.312 -35.138 1.00 50.02  ? 135 LEU G O   1 
ATOM   7472 C CB  . LEU E 5 135 ? -11.230 -60.111 -32.549 1.00 54.00  ? 135 LEU G CB  1 
ATOM   7473 C CG  . LEU E 5 135 ? -9.879  -59.720 -33.152 1.00 57.01  ? 135 LEU G CG  1 
ATOM   7474 C CD1 . LEU E 5 135 ? -9.516  -58.291 -32.787 1.00 53.65  ? 135 LEU G CD1 1 
ATOM   7475 C CD2 . LEU E 5 135 ? -8.791  -60.684 -32.703 1.00 54.63  ? 135 LEU G CD2 1 
ATOM   7476 N N   . LEU E 5 136 ? -12.247 -58.131 -35.117 1.00 49.30  ? 136 LEU G N   1 
ATOM   7477 C CA  . LEU E 5 136 ? -12.115 -57.973 -36.564 1.00 54.36  ? 136 LEU G CA  1 
ATOM   7478 C C   . LEU E 5 136 ? -10.665 -57.588 -36.836 1.00 54.22  ? 136 LEU G C   1 
ATOM   7479 O O   . LEU E 5 136 ? -10.266 -56.447 -36.586 1.00 54.73  ? 136 LEU G O   1 
ATOM   7480 C CB  . LEU E 5 136 ? -13.077 -56.916 -37.100 1.00 48.68  ? 136 LEU G CB  1 
ATOM   7481 C CG  . LEU E 5 136 ? -14.564 -57.231 -37.282 1.00 46.80  ? 136 LEU G CG  1 
ATOM   7482 C CD1 . LEU E 5 136 ? -15.257 -57.537 -35.960 1.00 52.06  ? 136 LEU G CD1 1 
ATOM   7483 C CD2 . LEU E 5 136 ? -15.248 -56.068 -37.983 1.00 45.12  ? 136 LEU G CD2 1 
ATOM   7484 N N   . ASN E 5 137 ? -9.882  -58.533 -37.346 1.00 58.45  ? 137 ASN G N   1 
ATOM   7485 C CA  . ASN E 5 137 ? -8.432  -58.402 -37.400 1.00 67.11  ? 137 ASN G CA  1 
ATOM   7486 C C   . ASN E 5 137 ? -7.952  -58.236 -38.836 1.00 60.19  ? 137 ASN G C   1 
ATOM   7487 O O   . ASN E 5 137 ? -8.300  -59.040 -39.709 1.00 55.50  ? 137 ASN G O   1 
ATOM   7488 C CB  . ASN E 5 137 ? -7.760  -59.621 -36.763 1.00 61.36  ? 137 ASN G CB  1 
ATOM   7489 C CG  . ASN E 5 137 ? -6.316  -59.362 -36.397 1.00 63.70  ? 137 ASN G CG  1 
ATOM   7490 O OD1 . ASN E 5 137 ? -5.956  -58.254 -35.997 1.00 70.55  ? 137 ASN G OD1 1 
ATOM   7491 N ND2 . ASN E 5 137 ? -5.478  -60.381 -36.534 1.00 65.95  ? 137 ASN G ND2 1 
ATOM   7492 N N   . ASN E 5 138 ? -7.146  -57.196 -39.068 1.00 61.23  ? 138 ASN G N   1 
ATOM   7493 C CA  . ASN E 5 138 ? -6.397  -56.999 -40.312 1.00 64.94  ? 138 ASN G CA  1 
ATOM   7494 C C   . ASN E 5 138 ? -7.332  -56.949 -41.526 1.00 59.24  ? 138 ASN G C   1 
ATOM   7495 O O   . ASN E 5 138 ? -7.316  -57.812 -42.406 1.00 64.29  ? 138 ASN G O   1 
ATOM   7496 C CB  . ASN E 5 138 ? -5.329  -58.087 -40.476 1.00 60.80  ? 138 ASN G CB  1 
ATOM   7497 C CG  . ASN E 5 138 ? -4.249  -58.004 -39.415 1.00 65.39  ? 138 ASN G CG  1 
ATOM   7498 O OD1 . ASN E 5 138 ? -3.880  -56.915 -38.974 1.00 55.00  ? 138 ASN G OD1 1 
ATOM   7499 N ND2 . ASN E 5 138 ? -3.738  -59.156 -38.997 1.00 60.02  ? 138 ASN G ND2 1 
ATOM   7500 N N   . PHE E 5 139 ? -8.154  -55.902 -41.548 1.00 50.06  ? 139 PHE G N   1 
ATOM   7501 C CA  . PHE E 5 139 ? -9.099  -55.692 -42.634 1.00 53.98  ? 139 PHE G CA  1 
ATOM   7502 C C   . PHE E 5 139 ? -8.964  -54.283 -43.192 1.00 51.12  ? 139 PHE G C   1 
ATOM   7503 O O   . PHE E 5 139 ? -8.464  -53.369 -42.532 1.00 50.85  ? 139 PHE G O   1 
ATOM   7504 C CB  . PHE E 5 139 ? -10.547 -55.931 -42.184 1.00 59.45  ? 139 PHE G CB  1 
ATOM   7505 C CG  . PHE E 5 139 ? -11.032 -54.968 -41.136 1.00 52.74  ? 139 PHE G CG  1 
ATOM   7506 C CD1 . PHE E 5 139 ? -10.753 -55.182 -39.796 1.00 55.23  ? 139 PHE G CD1 1 
ATOM   7507 C CD2 . PHE E 5 139 ? -11.783 -53.859 -41.489 1.00 43.04  ? 139 PHE G CD2 1 
ATOM   7508 C CE1 . PHE E 5 139 ? -11.204 -54.301 -38.831 1.00 43.42  ? 139 PHE G CE1 1 
ATOM   7509 C CE2 . PHE E 5 139 ? -12.235 -52.975 -40.529 1.00 37.82  ? 139 PHE G CE2 1 
ATOM   7510 C CZ  . PHE E 5 139 ? -11.946 -53.197 -39.199 1.00 36.82  ? 139 PHE G CZ  1 
ATOM   7511 N N   . TYR E 5 140 ? -9.423  -54.127 -44.435 1.00 57.82  ? 140 TYR G N   1 
ATOM   7512 C CA  . TYR E 5 140 ? -9.515  -52.851 -45.121 1.00 56.41  ? 140 TYR G CA  1 
ATOM   7513 C C   . TYR E 5 140 ? -10.645 -52.985 -46.129 1.00 51.54  ? 140 TYR G C   1 
ATOM   7514 O O   . TYR E 5 140 ? -10.759 -54.037 -46.775 1.00 55.66  ? 140 TYR G O   1 
ATOM   7515 C CB  . TYR E 5 140 ? -8.211  -52.466 -45.829 1.00 57.59  ? 140 TYR G CB  1 
ATOM   7516 C CG  . TYR E 5 140 ? -8.228  -51.070 -46.409 1.00 56.45  ? 140 TYR G CG  1 
ATOM   7517 C CD1 . TYR E 5 140 ? -7.912  -49.969 -45.625 1.00 61.55  ? 140 TYR G CD1 1 
ATOM   7518 C CD2 . TYR E 5 140 ? -8.571  -50.852 -47.737 1.00 60.85  ? 140 TYR G CD2 1 
ATOM   7519 C CE1 . TYR E 5 140 ? -7.932  -48.690 -46.146 1.00 62.79  ? 140 TYR G CE1 1 
ATOM   7520 C CE2 . TYR E 5 140 ? -8.594  -49.576 -48.268 1.00 65.05  ? 140 TYR G CE2 1 
ATOM   7521 C CZ  . TYR E 5 140 ? -8.273  -48.500 -47.469 1.00 64.83  ? 140 TYR G CZ  1 
ATOM   7522 O OH  . TYR E 5 140 ? -8.295  -47.228 -47.992 1.00 69.29  ? 140 TYR G OH  1 
ATOM   7523 N N   . PRO E 5 141 ? -11.492 -51.958 -46.295 1.00 48.89  ? 141 PRO G N   1 
ATOM   7524 C CA  . PRO E 5 141 ? -11.460 -50.631 -45.661 1.00 52.00  ? 141 PRO G CA  1 
ATOM   7525 C C   . PRO E 5 141 ? -11.940 -50.629 -44.213 1.00 51.29  ? 141 PRO G C   1 
ATOM   7526 O O   . PRO E 5 141 ? -12.311 -51.660 -43.660 1.00 46.28  ? 141 PRO G O   1 
ATOM   7527 C CB  . PRO E 5 141 ? -12.387 -49.808 -46.565 1.00 36.44  ? 141 PRO G CB  1 
ATOM   7528 C CG  . PRO E 5 141 ? -13.399 -50.803 -47.036 1.00 46.10  ? 141 PRO G CG  1 
ATOM   7529 C CD  . PRO E 5 141 ? -12.621 -52.082 -47.236 1.00 46.43  ? 141 PRO G CD  1 
ATOM   7530 N N   . ARG E 5 142 ? -11.930 -49.451 -43.583 1.00 52.41  ? 142 ARG G N   1 
ATOM   7531 C CA  . ARG E 5 142 ? -12.298 -49.343 -42.174 1.00 58.13  ? 142 ARG G CA  1 
ATOM   7532 C C   . ARG E 5 142 ? -13.786 -49.586 -41.953 1.00 57.14  ? 142 ARG G C   1 
ATOM   7533 O O   . ARG E 5 142 ? -14.178 -50.092 -40.895 1.00 48.48  ? 142 ARG G O   1 
ATOM   7534 C CB  . ARG E 5 142 ? -11.892 -47.967 -41.644 1.00 54.67  ? 142 ARG G CB  1 
ATOM   7535 C CG  . ARG E 5 142 ? -12.250 -47.700 -40.191 1.00 63.22  ? 142 ARG G CG  1 
ATOM   7536 C CD  . ARG E 5 142 ? -11.859 -46.285 -39.796 1.00 69.69  ? 142 ARG G CD  1 
ATOM   7537 N NE  . ARG E 5 142 ? -10.613 -46.247 -39.041 1.00 84.39  ? 142 ARG G NE  1 
ATOM   7538 C CZ  . ARG E 5 142 ? -10.506 -45.813 -37.793 1.00 87.49  ? 142 ARG G CZ  1 
ATOM   7539 N NH1 . ARG E 5 142 ? -11.550 -45.331 -37.138 1.00 79.27  ? 142 ARG G NH1 1 
ATOM   7540 N NH2 . ARG E 5 142 ? -9.321  -45.854 -37.191 1.00 71.73  ? 142 ARG G NH2 1 
ATOM   7541 N N   . GLU E 5 143 ? -14.624 -49.240 -42.930 1.00 61.42  ? 143 GLU G N   1 
ATOM   7542 C CA  . GLU E 5 143 ? -16.067 -49.394 -42.783 1.00 55.20  ? 143 GLU G CA  1 
ATOM   7543 C C   . GLU E 5 143 ? -16.443 -50.860 -42.615 1.00 50.79  ? 143 GLU G C   1 
ATOM   7544 O O   . GLU E 5 143 ? -16.147 -51.691 -43.479 1.00 53.31  ? 143 GLU G O   1 
ATOM   7545 C CB  . GLU E 5 143 ? -16.785 -48.799 -43.994 1.00 55.35  ? 143 GLU G CB  1 
ATOM   7546 C CG  . GLU E 5 143 ? -17.055 -47.304 -43.905 1.00 69.69  ? 143 GLU G CG  1 
ATOM   7547 C CD  . GLU E 5 143 ? -18.337 -46.978 -43.156 1.00 73.77  ? 143 GLU G CD  1 
ATOM   7548 O OE1 . GLU E 5 143 ? -18.716 -47.743 -42.243 1.00 73.63  ? 143 GLU G OE1 1 
ATOM   7549 O OE2 . GLU E 5 143 ? -18.973 -45.956 -43.489 1.00 66.58  ? 143 GLU G OE2 1 
ATOM   7550 N N   . ALA E 5 144 ? -17.103 -51.170 -41.501 1.00 51.13  ? 144 ALA G N   1 
ATOM   7551 C CA  . ALA E 5 144 ? -17.566 -52.522 -41.225 1.00 56.11  ? 144 ALA G CA  1 
ATOM   7552 C C   . ALA E 5 144 ? -18.712 -52.451 -40.227 1.00 51.77  ? 144 ALA G C   1 
ATOM   7553 O O   . ALA E 5 144 ? -18.681 -51.641 -39.297 1.00 48.30  ? 144 ALA G O   1 
ATOM   7554 C CB  . ALA E 5 144 ? -16.436 -53.403 -40.679 1.00 53.08  ? 144 ALA G CB  1 
ATOM   7555 N N   . LYS E 5 145 ? -19.715 -53.300 -40.426 1.00 53.35  ? 145 LYS G N   1 
ATOM   7556 C CA  . LYS E 5 145 ? -20.863 -53.382 -39.534 1.00 43.34  ? 145 LYS G CA  1 
ATOM   7557 C C   . LYS E 5 145 ? -20.704 -54.579 -38.608 1.00 43.63  ? 145 LYS G C   1 
ATOM   7558 O O   . LYS E 5 145 ? -20.496 -55.706 -39.072 1.00 42.73  ? 145 LYS G O   1 
ATOM   7559 C CB  . LYS E 5 145 ? -22.170 -53.502 -40.319 1.00 48.53  ? 145 LYS G CB  1 
ATOM   7560 C CG  . LYS E 5 145 ? -23.363 -53.882 -39.451 1.00 52.93  ? 145 LYS G CG  1 
ATOM   7561 C CD  . LYS E 5 145 ? -24.531 -54.397 -40.279 1.00 65.88  ? 145 LYS G CD  1 
ATOM   7562 C CE  . LYS E 5 145 ? -25.391 -53.262 -40.807 1.00 66.54  ? 145 LYS G CE  1 
ATOM   7563 N NZ  . LYS E 5 145 ? -26.778 -53.331 -40.265 1.00 62.99  ? 145 LYS G NZ  1 
ATOM   7564 N N   . VAL E 5 146 ? -20.802 -54.333 -37.305 1.00 37.63  ? 146 VAL G N   1 
ATOM   7565 C CA  . VAL E 5 146 ? -20.753 -55.381 -36.293 1.00 38.75  ? 146 VAL G CA  1 
ATOM   7566 C C   . VAL E 5 146 ? -22.091 -55.388 -35.571 1.00 38.91  ? 146 VAL G C   1 
ATOM   7567 O O   . VAL E 5 146 ? -22.493 -54.374 -34.987 1.00 43.36  ? 146 VAL G O   1 
ATOM   7568 C CB  . VAL E 5 146 ? -19.595 -55.172 -35.305 1.00 41.46  ? 146 VAL G CB  1 
ATOM   7569 C CG1 . VAL E 5 146 ? -19.526 -56.328 -34.317 1.00 33.32  ? 146 VAL G CG1 1 
ATOM   7570 C CG2 . VAL E 5 146 ? -18.281 -55.021 -36.052 1.00 35.13  ? 146 VAL G CG2 1 
ATOM   7571 N N   . GLN E 5 147 ? -22.778 -56.526 -35.612 1.00 39.26  ? 147 GLN G N   1 
ATOM   7572 C CA  . GLN E 5 147 ? -24.073 -56.692 -34.968 1.00 34.96  ? 147 GLN G CA  1 
ATOM   7573 C C   . GLN E 5 147 ? -23.987 -57.819 -33.952 1.00 33.50  ? 147 GLN G C   1 
ATOM   7574 O O   . GLN E 5 147 ? -23.514 -58.914 -34.273 1.00 39.67  ? 147 GLN G O   1 
ATOM   7575 C CB  . GLN E 5 147 ? -25.171 -56.992 -35.993 1.00 40.43  ? 147 GLN G CB  1 
ATOM   7576 C CG  . GLN E 5 147 ? -25.577 -55.801 -36.845 1.00 52.44  ? 147 GLN G CG  1 
ATOM   7577 C CD  . GLN E 5 147 ? -26.727 -56.124 -37.778 1.00 68.48  ? 147 GLN G CD  1 
ATOM   7578 O OE1 . GLN E 5 147 ? -27.580 -55.278 -38.046 1.00 72.66  ? 147 GLN G OE1 1 
ATOM   7579 N NE2 . GLN E 5 147 ? -26.756 -57.354 -38.280 1.00 56.98  ? 147 GLN G NE2 1 
ATOM   7580 N N   . TRP E 5 148 ? -24.443 -57.549 -32.734 1.00 27.27  ? 148 TRP G N   1 
ATOM   7581 C CA  . TRP E 5 148 ? -24.514 -58.566 -31.694 1.00 27.01  ? 148 TRP G CA  1 
ATOM   7582 C C   . TRP E 5 148 ? -25.900 -59.197 -31.711 1.00 30.18  ? 148 TRP G C   1 
ATOM   7583 O O   . TRP E 5 148 ? -26.909 -58.496 -31.576 1.00 29.69  ? 148 TRP G O   1 
ATOM   7584 C CB  . TRP E 5 148 ? -24.212 -57.968 -30.321 1.00 29.61  ? 148 TRP G CB  1 
ATOM   7585 C CG  . TRP E 5 148 ? -22.754 -57.759 -30.068 1.00 37.31  ? 148 TRP G CG  1 
ATOM   7586 C CD1 . TRP E 5 148 ? -22.073 -56.578 -30.116 1.00 35.52  ? 148 TRP G CD1 1 
ATOM   7587 C CD2 . TRP E 5 148 ? -21.791 -58.765 -29.730 1.00 33.78  ? 148 TRP G CD2 1 
ATOM   7588 N NE1 . TRP E 5 148 ? -20.746 -56.785 -29.826 1.00 38.73  ? 148 TRP G NE1 1 
ATOM   7589 C CE2 . TRP E 5 148 ? -20.547 -58.119 -29.586 1.00 36.81  ? 148 TRP G CE2 1 
ATOM   7590 C CE3 . TRP E 5 148 ? -21.861 -60.147 -29.534 1.00 36.95  ? 148 TRP G CE3 1 
ATOM   7591 C CZ2 . TRP E 5 148 ? -19.383 -58.809 -29.254 1.00 37.84  ? 148 TRP G CZ2 1 
ATOM   7592 C CZ3 . TRP E 5 148 ? -20.704 -60.830 -29.206 1.00 44.14  ? 148 TRP G CZ3 1 
ATOM   7593 C CH2 . TRP E 5 148 ? -19.482 -60.161 -29.071 1.00 38.83  ? 148 TRP G CH2 1 
ATOM   7594 N N   . LYS E 5 149 ? -25.948 -60.513 -31.886 1.00 30.19  ? 149 LYS G N   1 
ATOM   7595 C CA  . LYS E 5 149 ? -27.194 -61.267 -31.842 1.00 32.22  ? 149 LYS G CA  1 
ATOM   7596 C C   . LYS E 5 149 ? -27.092 -62.297 -30.731 1.00 38.06  ? 149 LYS G C   1 
ATOM   7597 O O   . LYS E 5 149 ? -26.190 -63.142 -30.744 1.00 38.84  ? 149 LYS G O   1 
ATOM   7598 C CB  . LYS E 5 149 ? -27.481 -61.950 -33.179 1.00 29.72  ? 149 LYS G CB  1 
ATOM   7599 C CG  . LYS E 5 149 ? -27.660 -61.002 -34.348 1.00 41.45  ? 149 LYS G CG  1 
ATOM   7600 C CD  . LYS E 5 149 ? -28.593 -61.622 -35.370 1.00 47.22  ? 149 LYS G CD  1 
ATOM   7601 C CE  . LYS E 5 149 ? -28.401 -61.028 -36.750 1.00 63.64  ? 149 LYS G CE  1 
ATOM   7602 N NZ  . LYS E 5 149 ? -29.156 -61.810 -37.769 1.00 60.51  ? 149 LYS G NZ  1 
ATOM   7603 N N   . VAL E 5 150 ? -28.011 -62.226 -29.774 1.00 27.08  ? 150 VAL G N   1 
ATOM   7604 C CA  . VAL E 5 150 ? -28.065 -63.162 -28.660 1.00 32.67  ? 150 VAL G CA  1 
ATOM   7605 C C   . VAL E 5 150 ? -29.389 -63.907 -28.750 1.00 33.75  ? 150 VAL G C   1 
ATOM   7606 O O   . VAL E 5 150 ? -30.459 -63.290 -28.669 1.00 34.82  ? 150 VAL G O   1 
ATOM   7607 C CB  . VAL E 5 150 ? -27.916 -62.448 -27.308 1.00 33.97  ? 150 VAL G CB  1 
ATOM   7608 C CG1 . VAL E 5 150 ? -27.587 -63.445 -26.234 1.00 40.55  ? 150 VAL G CG1 1 
ATOM   7609 C CG2 . VAL E 5 150 ? -26.829 -61.391 -27.389 1.00 36.87  ? 150 VAL G CG2 1 
ATOM   7610 N N   . ASP E 5 151 ? -29.314 -65.229 -28.913 1.00 34.20  ? 151 ASP G N   1 
ATOM   7611 C CA  . ASP E 5 151 ? -30.486 -66.057 -29.203 1.00 30.05  ? 151 ASP G CA  1 
ATOM   7612 C C   . ASP E 5 151 ? -31.235 -65.528 -30.425 1.00 28.87  ? 151 ASP G C   1 
ATOM   7613 O O   . ASP E 5 151 ? -32.467 -65.494 -30.462 1.00 38.11  ? 151 ASP G O   1 
ATOM   7614 C CB  . ASP E 5 151 ? -31.411 -66.154 -27.987 1.00 26.75  ? 151 ASP G CB  1 
ATOM   7615 C CG  . ASP E 5 151 ? -30.798 -66.949 -26.849 1.00 40.95  ? 151 ASP G CG  1 
ATOM   7616 O OD1 . ASP E 5 151 ? -30.053 -67.913 -27.127 1.00 35.66  ? 151 ASP G OD1 1 
ATOM   7617 O OD2 . ASP E 5 151 ? -31.063 -66.611 -25.676 1.00 41.51  ? 151 ASP G OD2 1 
ATOM   7618 N N   . ASN E 5 152 ? -30.469 -65.102 -31.432 1.00 31.97  ? 152 ASN G N   1 
ATOM   7619 C CA  . ASN E 5 152 ? -30.978 -64.541 -32.684 1.00 34.04  ? 152 ASN G CA  1 
ATOM   7620 C C   . ASN E 5 152 ? -31.764 -63.251 -32.475 1.00 33.26  ? 152 ASN G C   1 
ATOM   7621 O O   . ASN E 5 152 ? -32.505 -62.822 -33.366 1.00 37.14  ? 152 ASN G O   1 
ATOM   7622 C CB  . ASN E 5 152 ? -31.826 -65.558 -33.456 1.00 34.01  ? 152 ASN G CB  1 
ATOM   7623 C CG  . ASN E 5 152 ? -31.042 -66.259 -34.546 1.00 49.77  ? 152 ASN G CG  1 
ATOM   7624 O OD1 . ASN E 5 152 ? -30.821 -67.468 -34.490 1.00 60.50  ? 152 ASN G OD1 1 
ATOM   7625 N ND2 . ASN E 5 152 ? -30.613 -65.498 -35.547 1.00 58.15  ? 152 ASN G ND2 1 
ATOM   7626 N N   . ALA E 5 153 ? -31.611 -62.616 -31.317 1.00 25.18  ? 153 ALA G N   1 
ATOM   7627 C CA  . ALA E 5 153 ? -32.211 -61.316 -31.051 1.00 27.09  ? 153 ALA G CA  1 
ATOM   7628 C C   . ALA E 5 153 ? -31.132 -60.245 -31.139 1.00 36.92  ? 153 ALA G C   1 
ATOM   7629 O O   . ALA E 5 153 ? -30.079 -60.363 -30.503 1.00 36.51  ? 153 ALA G O   1 
ATOM   7630 C CB  . ALA E 5 153 ? -32.879 -61.289 -29.676 1.00 26.73  ? 153 ALA G CB  1 
ATOM   7631 N N   . LEU E 5 154 ? -31.394 -59.208 -31.930 1.00 29.44  ? 154 LEU G N   1 
ATOM   7632 C CA  . LEU E 5 154 ? -30.418 -58.142 -32.118 1.00 30.30  ? 154 LEU G CA  1 
ATOM   7633 C C   . LEU E 5 154 ? -30.295 -57.323 -30.838 1.00 27.46  ? 154 LEU G C   1 
ATOM   7634 O O   . LEU E 5 154 ? -31.271 -56.719 -30.382 1.00 35.94  ? 154 LEU G O   1 
ATOM   7635 C CB  . LEU E 5 154 ? -30.824 -57.255 -33.292 1.00 29.03  ? 154 LEU G CB  1 
ATOM   7636 C CG  . LEU E 5 154 ? -29.923 -56.056 -33.592 1.00 38.94  ? 154 LEU G CG  1 
ATOM   7637 C CD1 . LEU E 5 154 ? -28.489 -56.502 -33.837 1.00 28.82  ? 154 LEU G CD1 1 
ATOM   7638 C CD2 . LEU E 5 154 ? -30.454 -55.276 -34.783 1.00 29.78  ? 154 LEU G CD2 1 
ATOM   7639 N N   . GLN E 5 155 ? -29.095 -57.302 -30.263 1.00 25.86  ? 155 GLN G N   1 
ATOM   7640 C CA  . GLN E 5 155 ? -28.826 -56.600 -29.015 1.00 32.09  ? 155 GLN G CA  1 
ATOM   7641 C C   . GLN E 5 155 ? -28.196 -55.247 -29.311 1.00 32.08  ? 155 GLN G C   1 
ATOM   7642 O O   . GLN E 5 155 ? -27.259 -55.154 -30.112 1.00 41.15  ? 155 GLN G O   1 
ATOM   7643 C CB  . GLN E 5 155 ? -27.905 -57.425 -28.115 1.00 25.55  ? 155 GLN G CB  1 
ATOM   7644 C CG  . GLN E 5 155 ? -28.637 -58.331 -27.141 1.00 40.51  ? 155 GLN G CG  1 
ATOM   7645 C CD  . GLN E 5 155 ? -29.007 -57.622 -25.854 1.00 39.35  ? 155 GLN G CD  1 
ATOM   7646 O OE1 . GLN E 5 155 ? -28.775 -56.423 -25.704 1.00 38.47  ? 155 GLN G OE1 1 
ATOM   7647 N NE2 . GLN E 5 155 ? -29.579 -58.363 -24.912 1.00 41.97  ? 155 GLN G NE2 1 
ATOM   7648 N N   . SER E 5 156 ? -28.710 -54.203 -28.664 1.00 28.76  ? 156 SER G N   1 
ATOM   7649 C CA  . SER E 5 156 ? -28.227 -52.847 -28.873 1.00 26.95  ? 156 SER G CA  1 
ATOM   7650 C C   . SER E 5 156 ? -28.083 -52.142 -27.533 1.00 28.40  ? 156 SER G C   1 
ATOM   7651 O O   . SER E 5 156 ? -28.736 -52.493 -26.547 1.00 31.81  ? 156 SER G O   1 
ATOM   7652 C CB  . SER E 5 156 ? -29.169 -52.048 -29.785 1.00 29.51  ? 156 SER G CB  1 
ATOM   7653 O OG  . SER E 5 156 ? -29.367 -52.709 -31.022 1.00 55.55  ? 156 SER G OG  1 
ATOM   7654 N N   . GLY E 5 157 ? -27.205 -51.140 -27.509 1.00 28.24  ? 157 GLY G N   1 
ATOM   7655 C CA  . GLY E 5 157 ? -27.081 -50.244 -26.380 1.00 35.78  ? 157 GLY G CA  1 
ATOM   7656 C C   . GLY E 5 157 ? -26.159 -50.692 -25.268 1.00 35.60  ? 157 GLY G C   1 
ATOM   7657 O O   . GLY E 5 157 ? -25.964 -49.934 -24.309 1.00 43.44  ? 157 GLY G O   1 
ATOM   7658 N N   . ASN E 5 158 ? -25.582 -51.890 -25.357 1.00 27.19  ? 158 ASN G N   1 
ATOM   7659 C CA  . ASN E 5 158 ? -24.700 -52.395 -24.312 1.00 33.72  ? 158 ASN G CA  1 
ATOM   7660 C C   . ASN E 5 158 ? -23.367 -52.857 -24.889 1.00 35.92  ? 158 ASN G C   1 
ATOM   7661 O O   . ASN E 5 158 ? -22.710 -53.737 -24.327 1.00 31.08  ? 158 ASN G O   1 
ATOM   7662 C CB  . ASN E 5 158 ? -25.372 -53.525 -23.532 1.00 36.73  ? 158 ASN G CB  1 
ATOM   7663 C CG  . ASN E 5 158 ? -25.883 -54.631 -24.434 1.00 43.48  ? 158 ASN G CG  1 
ATOM   7664 O OD1 . ASN E 5 158 ? -25.919 -54.485 -25.656 1.00 36.01  ? 158 ASN G OD1 1 
ATOM   7665 N ND2 . ASN E 5 158 ? -26.293 -55.742 -23.833 1.00 45.10  ? 158 ASN G ND2 1 
ATOM   7666 N N   . SER E 5 159 ? -22.956 -52.272 -26.012 1.00 25.16  ? 159 SER G N   1 
ATOM   7667 C CA  . SER E 5 159 ? -21.699 -52.615 -26.656 1.00 28.66  ? 159 SER G CA  1 
ATOM   7668 C C   . SER E 5 159 ? -20.942 -51.347 -27.020 1.00 29.80  ? 159 SER G C   1 
ATOM   7669 O O   . SER E 5 159 ? -21.540 -50.319 -27.350 1.00 30.92  ? 159 SER G O   1 
ATOM   7670 C CB  . SER E 5 159 ? -21.925 -53.466 -27.913 1.00 25.89  ? 159 SER G CB  1 
ATOM   7671 O OG  . SER E 5 159 ? -22.739 -52.782 -28.849 1.00 32.60  ? 159 SER G OG  1 
ATOM   7672 N N   . GLN E 5 160 ? -19.616 -51.432 -26.953 1.00 32.04  ? 160 GLN G N   1 
ATOM   7673 C CA  . GLN E 5 160 ? -18.734 -50.338 -27.328 1.00 27.26  ? 160 GLN G CA  1 
ATOM   7674 C C   . GLN E 5 160 ? -17.673 -50.855 -28.287 1.00 26.54  ? 160 GLN G C   1 
ATOM   7675 O O   . GLN E 5 160 ? -17.237 -52.006 -28.194 1.00 29.53  ? 160 GLN G O   1 
ATOM   7676 C CB  . GLN E 5 160 ? -18.076 -49.695 -26.100 1.00 23.99  ? 160 GLN G CB  1 
ATOM   7677 C CG  . GLN E 5 160 ? -19.029 -48.852 -25.269 1.00 33.92  ? 160 GLN G CG  1 
ATOM   7678 C CD  . GLN E 5 160 ? -18.361 -48.232 -24.059 1.00 55.44  ? 160 GLN G CD  1 
ATOM   7679 O OE1 . GLN E 5 160 ? -17.810 -48.934 -23.210 1.00 53.63  ? 160 GLN G OE1 1 
ATOM   7680 N NE2 . GLN E 5 160 ? -18.403 -46.906 -23.974 1.00 45.16  ? 160 GLN G NE2 1 
ATOM   7681 N N   . GLU E 5 161 ? -17.262 -49.993 -29.212 1.00 39.82  ? 161 GLU G N   1 
ATOM   7682 C CA  . GLU E 5 161 ? -16.354 -50.369 -30.285 1.00 41.92  ? 161 GLU G CA  1 
ATOM   7683 C C   . GLU E 5 161 ? -15.064 -49.567 -30.199 1.00 42.08  ? 161 GLU G C   1 
ATOM   7684 O O   . GLU E 5 161 ? -15.082 -48.370 -29.894 1.00 28.95  ? 161 GLU G O   1 
ATOM   7685 C CB  . GLU E 5 161 ? -17.007 -50.160 -31.655 1.00 33.87  ? 161 GLU G CB  1 
ATOM   7686 C CG  . GLU E 5 161 ? -17.185 -51.443 -32.446 1.00 55.78  ? 161 GLU G CG  1 
ATOM   7687 C CD  . GLU E 5 161 ? -18.136 -51.285 -33.614 1.00 59.13  ? 161 GLU G CD  1 
ATOM   7688 O OE1 . GLU E 5 161 ? -18.201 -50.179 -34.190 1.00 58.72  ? 161 GLU G OE1 1 
ATOM   7689 O OE2 . GLU E 5 161 ? -18.829 -52.269 -33.950 1.00 63.05  ? 161 GLU G OE2 1 
ATOM   7690 N N   . SER E 5 162 ? -13.948 -50.240 -30.465 1.00 36.92  ? 162 SER G N   1 
ATOM   7691 C CA  . SER E 5 162 ? -12.635 -49.613 -30.526 1.00 36.14  ? 162 SER G CA  1 
ATOM   7692 C C   . SER E 5 162 ? -11.915 -50.125 -31.763 1.00 40.53  ? 162 SER G C   1 
ATOM   7693 O O   . SER E 5 162 ? -11.907 -51.332 -32.025 1.00 43.49  ? 162 SER G O   1 
ATOM   7694 C CB  . SER E 5 162 ? -11.817 -49.910 -29.266 1.00 34.69  ? 162 SER G CB  1 
ATOM   7695 O OG  . SER E 5 162 ? -10.591 -49.201 -29.275 1.00 46.79  ? 162 SER G OG  1 
ATOM   7696 N N   . VAL E 5 163 ? -11.315 -49.210 -32.522 1.00 38.58  ? 163 VAL G N   1 
ATOM   7697 C CA  . VAL E 5 163 ? -10.631 -49.543 -33.766 1.00 49.50  ? 163 VAL G CA  1 
ATOM   7698 C C   . VAL E 5 163 ? -9.231  -48.945 -33.726 1.00 45.43  ? 163 VAL G C   1 
ATOM   7699 O O   . VAL E 5 163 ? -9.058  -47.777 -33.360 1.00 44.62  ? 163 VAL G O   1 
ATOM   7700 C CB  . VAL E 5 163 ? -11.415 -49.044 -34.997 1.00 48.44  ? 163 VAL G CB  1 
ATOM   7701 C CG1 . VAL E 5 163 ? -11.838 -47.595 -34.814 1.00 43.48  ? 163 VAL G CG1 1 
ATOM   7702 C CG2 . VAL E 5 163 ? -10.595 -49.219 -36.267 1.00 51.84  ? 163 VAL G CG2 1 
ATOM   7703 N N   . THR E 5 164 ? -8.235  -49.750 -34.090 1.00 41.45  ? 164 THR G N   1 
ATOM   7704 C CA  . THR E 5 164 ? -6.845  -49.325 -34.056 1.00 47.17  ? 164 THR G CA  1 
ATOM   7705 C C   . THR E 5 164 ? -6.522  -48.417 -35.241 1.00 56.56  ? 164 THR G C   1 
ATOM   7706 O O   . THR E 5 164 ? -7.308  -48.261 -36.179 1.00 53.43  ? 164 THR G O   1 
ATOM   7707 C CB  . THR E 5 164 ? -5.909  -50.534 -34.063 1.00 45.48  ? 164 THR G CB  1 
ATOM   7708 O OG1 . THR E 5 164 ? -6.178  -51.341 -35.217 1.00 43.95  ? 164 THR G OG1 1 
ATOM   7709 C CG2 . THR E 5 164 ? -6.101  -51.368 -32.807 1.00 51.33  ? 164 THR G CG2 1 
ATOM   7710 N N   . GLU E 5 165 ? -5.340  -47.809 -35.182 1.00 69.90  ? 165 GLU G N   1 
ATOM   7711 C CA  . GLU E 5 165 ? -4.854  -46.985 -36.276 1.00 63.73  ? 165 GLU G CA  1 
ATOM   7712 C C   . GLU E 5 165 ? -4.392  -47.868 -37.434 1.00 64.62  ? 165 GLU G C   1 
ATOM   7713 O O   . GLU E 5 165 ? -4.261  -49.089 -37.310 1.00 59.27  ? 165 GLU G O   1 
ATOM   7714 C CB  . GLU E 5 165 ? -3.711  -46.088 -35.804 1.00 62.38  ? 165 GLU G CB  1 
ATOM   7715 C CG  . GLU E 5 165 ? -3.962  -45.425 -34.461 1.00 63.29  ? 165 GLU G CG  1 
ATOM   7716 C CD  . GLU E 5 165 ? -5.216  -44.576 -34.458 1.00 73.29  ? 165 GLU G CD  1 
ATOM   7717 O OE1 . GLU E 5 165 ? -5.296  -43.626 -35.264 1.00 70.24  ? 165 GLU G OE1 1 
ATOM   7718 O OE2 . GLU E 5 165 ? -6.128  -44.869 -33.656 1.00 87.40  ? 165 GLU G OE2 1 
ATOM   7719 N N   . GLN E 5 166 ? -4.156  -47.232 -38.580 1.00 57.66  ? 166 GLN G N   1 
ATOM   7720 C CA  . GLN E 5 166 ? -3.633  -47.953 -39.733 1.00 59.77  ? 166 GLN G CA  1 
ATOM   7721 C C   . GLN E 5 166 ? -2.276  -48.559 -39.408 1.00 64.29  ? 166 GLN G C   1 
ATOM   7722 O O   . GLN E 5 166 ? -1.404  -47.894 -38.839 1.00 82.64  ? 166 GLN G O   1 
ATOM   7723 C CB  . GLN E 5 166 ? -3.511  -47.022 -40.939 1.00 61.84  ? 166 GLN G CB  1 
ATOM   7724 C CG  . GLN E 5 166 ? -4.805  -46.804 -41.689 1.00 62.93  ? 166 GLN G CG  1 
ATOM   7725 C CD  . GLN E 5 166 ? -4.608  -46.796 -43.191 1.00 65.55  ? 166 GLN G CD  1 
ATOM   7726 O OE1 . GLN E 5 166 ? -4.354  -45.751 -43.790 1.00 70.33  ? 166 GLN G OE1 1 
ATOM   7727 N NE2 . GLN E 5 166 ? -4.721  -47.966 -43.809 1.00 59.07  ? 166 GLN G NE2 1 
ATOM   7728 N N   . ASP E 5 167 ? -2.102  -49.827 -39.767 1.00 59.92  ? 167 ASP G N   1 
ATOM   7729 C CA  . ASP E 5 167 ? -0.816  -50.479 -39.576 1.00 76.07  ? 167 ASP G CA  1 
ATOM   7730 C C   . ASP E 5 167 ? 0.236   -49.820 -40.462 1.00 88.92  ? 167 ASP G C   1 
ATOM   7731 O O   . ASP E 5 167 ? -0.055  -49.340 -41.560 1.00 83.27  ? 167 ASP G O   1 
ATOM   7732 C CB  . ASP E 5 167 ? -0.927  -51.972 -39.889 1.00 79.46  ? 167 ASP G CB  1 
ATOM   7733 C CG  . ASP E 5 167 ? 0.158   -52.793 -39.217 1.00 91.07  ? 167 ASP G CG  1 
ATOM   7734 O OD1 . ASP E 5 167 ? 1.289   -52.285 -39.062 1.00 89.08  ? 167 ASP G OD1 1 
ATOM   7735 O OD2 . ASP E 5 167 ? -0.123  -53.951 -38.841 1.00 88.81  ? 167 ASP G OD2 1 
ATOM   7736 N N   . SER E 5 168 ? 1.473   -49.784 -39.964 1.00 98.87  ? 168 SER G N   1 
ATOM   7737 C CA  . SER E 5 168 ? 2.529   -49.084 -40.686 1.00 97.57  ? 168 SER G CA  1 
ATOM   7738 C C   . SER E 5 168 ? 2.970   -49.842 -41.932 1.00 101.03 ? 168 SER G C   1 
ATOM   7739 O O   . SER E 5 168 ? 3.447   -49.225 -42.891 1.00 89.70  ? 168 SER G O   1 
ATOM   7740 C CB  . SER E 5 168 ? 3.724   -48.840 -39.764 1.00 90.01  ? 168 SER G CB  1 
ATOM   7741 O OG  . SER E 5 168 ? 3.361   -48.018 -38.668 1.00 83.37  ? 168 SER G OG  1 
ATOM   7742 N N   . LYS E 5 169 ? 2.817   -51.167 -41.946 1.00 100.76 ? 169 LYS G N   1 
ATOM   7743 C CA  . LYS E 5 169 ? 3.332   -51.990 -43.036 1.00 100.35 ? 169 LYS G CA  1 
ATOM   7744 C C   . LYS E 5 169 ? 2.255   -52.357 -44.053 1.00 105.12 ? 169 LYS G C   1 
ATOM   7745 O O   . LYS E 5 169 ? 2.379   -52.026 -45.236 1.00 107.57 ? 169 LYS G O   1 
ATOM   7746 C CB  . LYS E 5 169 ? 3.985   -53.257 -42.465 1.00 107.13 ? 169 LYS G CB  1 
ATOM   7747 C CG  . LYS E 5 169 ? 4.587   -54.173 -43.516 1.00 116.35 ? 169 LYS G CG  1 
ATOM   7748 C CD  . LYS E 5 169 ? 5.396   -55.288 -42.876 1.00 122.75 ? 169 LYS G CD  1 
ATOM   7749 C CE  . LYS E 5 169 ? 6.550   -54.728 -42.059 1.00 124.87 ? 169 LYS G CE  1 
ATOM   7750 N NZ  . LYS E 5 169 ? 7.366   -55.805 -41.432 1.00 130.17 ? 169 LYS G NZ  1 
ATOM   7751 N N   . ASP E 5 170 ? 1.194   -53.033 -43.615 1.00 100.63 ? 170 ASP G N   1 
ATOM   7752 C CA  . ASP E 5 170 ? 0.138   -53.475 -44.517 1.00 95.15  ? 170 ASP G CA  1 
ATOM   7753 C C   . ASP E 5 170 ? -1.079  -52.559 -44.512 1.00 71.30  ? 170 ASP G C   1 
ATOM   7754 O O   . ASP E 5 170 ? -2.044  -52.838 -45.230 1.00 73.66  ? 170 ASP G O   1 
ATOM   7755 C CB  . ASP E 5 170 ? -0.287  -54.909 -44.177 1.00 80.99  ? 170 ASP G CB  1 
ATOM   7756 C CG  . ASP E 5 170 ? -0.485  -55.125 -42.691 1.00 82.58  ? 170 ASP G CG  1 
ATOM   7757 O OD1 . ASP E 5 170 ? -0.097  -54.237 -41.906 1.00 83.08  ? 170 ASP G OD1 1 
ATOM   7758 O OD2 . ASP E 5 170 ? -1.028  -56.183 -42.309 1.00 80.69  ? 170 ASP G OD2 1 
ATOM   7759 N N   . SER E 5 171 ? -1.056  -51.481 -43.725 1.00 73.32  ? 171 SER G N   1 
ATOM   7760 C CA  . SER E 5 171 ? -2.114  -50.467 -43.718 1.00 73.05  ? 171 SER G CA  1 
ATOM   7761 C C   . SER E 5 171 ? -3.487  -51.062 -43.411 1.00 76.03  ? 171 SER G C   1 
ATOM   7762 O O   . SER E 5 171 ? -4.508  -50.584 -43.912 1.00 68.72  ? 171 SER G O   1 
ATOM   7763 C CB  . SER E 5 171 ? -2.152  -49.701 -45.044 1.00 61.82  ? 171 SER G CB  1 
ATOM   7764 O OG  . SER E 5 171 ? -0.910  -49.069 -45.303 1.00 76.39  ? 171 SER G OG  1 
ATOM   7765 N N   . THR E 5 172 ? -3.528  -52.100 -42.583 1.00 71.75  ? 172 THR G N   1 
ATOM   7766 C CA  . THR E 5 172 ? -4.783  -52.743 -42.228 1.00 66.18  ? 172 THR G CA  1 
ATOM   7767 C C   . THR E 5 172 ? -5.338  -52.164 -40.932 1.00 62.13  ? 172 THR G C   1 
ATOM   7768 O O   . THR E 5 172 ? -4.625  -51.547 -40.138 1.00 57.70  ? 172 THR G O   1 
ATOM   7769 C CB  . THR E 5 172 ? -4.601  -54.255 -42.081 1.00 61.22  ? 172 THR G CB  1 
ATOM   7770 O OG1 . THR E 5 172 ? -3.768  -54.531 -40.948 1.00 63.26  ? 172 THR G OG1 1 
ATOM   7771 C CG2 . THR E 5 172 ? -3.959  -54.838 -43.327 1.00 66.84  ? 172 THR G CG2 1 
ATOM   7772 N N   . TYR E 5 173 ? -6.634  -52.376 -40.727 1.00 60.90  ? 173 TYR G N   1 
ATOM   7773 C CA  . TYR E 5 173 ? -7.324  -51.961 -39.518 1.00 53.63  ? 173 TYR G CA  1 
ATOM   7774 C C   . TYR E 5 173 ? -7.646  -53.170 -38.651 1.00 56.46  ? 173 TYR G C   1 
ATOM   7775 O O   . TYR E 5 173 ? -7.664  -54.313 -39.115 1.00 50.28  ? 173 TYR G O   1 
ATOM   7776 C CB  . TYR E 5 173 ? -8.621  -51.213 -39.846 1.00 41.55  ? 173 TYR G CB  1 
ATOM   7777 C CG  . TYR E 5 173 ? -8.427  -49.830 -40.417 1.00 49.04  ? 173 TYR G CG  1 
ATOM   7778 C CD1 . TYR E 5 173 ? -8.115  -48.756 -39.593 1.00 56.58  ? 173 TYR G CD1 1 
ATOM   7779 C CD2 . TYR E 5 173 ? -8.577  -49.591 -41.776 1.00 49.44  ? 173 TYR G CD2 1 
ATOM   7780 C CE1 . TYR E 5 173 ? -7.943  -47.487 -40.109 1.00 61.54  ? 173 TYR G CE1 1 
ATOM   7781 C CE2 . TYR E 5 173 ? -8.410  -48.325 -42.301 1.00 62.51  ? 173 TYR G CE2 1 
ATOM   7782 C CZ  . TYR E 5 173 ? -8.097  -47.277 -41.463 1.00 62.74  ? 173 TYR G CZ  1 
ATOM   7783 O OH  . TYR E 5 173 ? -7.928  -46.014 -41.983 1.00 58.24  ? 173 TYR G OH  1 
ATOM   7784 N N   . SER E 5 174 ? -7.901  -52.899 -37.374 1.00 49.25  ? 174 SER G N   1 
ATOM   7785 C CA  . SER E 5 174 ? -8.393  -53.904 -36.446 1.00 43.20  ? 174 SER G CA  1 
ATOM   7786 C C   . SER E 5 174 ? -9.473  -53.277 -35.580 1.00 46.77  ? 174 SER G C   1 
ATOM   7787 O O   . SER E 5 174 ? -9.318  -52.149 -35.104 1.00 49.11  ? 174 SER G O   1 
ATOM   7788 C CB  . SER E 5 174 ? -7.268  -54.473 -35.574 1.00 57.29  ? 174 SER G CB  1 
ATOM   7789 O OG  . SER E 5 174 ? -6.398  -55.291 -36.339 1.00 60.58  ? 174 SER G OG  1 
ATOM   7790 N N   . LEU E 5 175 ? -10.566 -54.010 -35.383 1.00 47.60  ? 175 LEU G N   1 
ATOM   7791 C CA  . LEU E 5 175 ? -11.718 -53.514 -34.645 1.00 44.81  ? 175 LEU G CA  1 
ATOM   7792 C C   . LEU E 5 175 ? -12.137 -54.538 -33.602 1.00 46.28  ? 175 LEU G C   1 
ATOM   7793 O O   . LEU E 5 175 ? -12.128 -55.745 -33.863 1.00 49.65  ? 175 LEU G O   1 
ATOM   7794 C CB  . LEU E 5 175 ? -12.890 -53.207 -35.595 1.00 44.62  ? 175 LEU G CB  1 
ATOM   7795 C CG  . LEU E 5 175 ? -14.166 -52.571 -35.035 1.00 43.32  ? 175 LEU G CG  1 
ATOM   7796 C CD1 . LEU E 5 175 ? -14.803 -51.673 -36.082 1.00 34.57  ? 175 LEU G CD1 1 
ATOM   7797 C CD2 . LEU E 5 175 ? -15.162 -53.629 -34.580 1.00 46.29  ? 175 LEU G CD2 1 
ATOM   7798 N N   . SER E 5 176 ? -12.504 -54.049 -32.420 1.00 44.95  ? 176 SER G N   1 
ATOM   7799 C CA  . SER E 5 176 ? -13.038 -54.885 -31.356 1.00 46.24  ? 176 SER G CA  1 
ATOM   7800 C C   . SER E 5 176 ? -14.360 -54.306 -30.877 1.00 43.38  ? 176 SER G C   1 
ATOM   7801 O O   . SER E 5 176 ? -14.490 -53.090 -30.708 1.00 41.65  ? 176 SER G O   1 
ATOM   7802 C CB  . SER E 5 176 ? -12.061 -54.996 -30.177 1.00 38.66  ? 176 SER G CB  1 
ATOM   7803 O OG  . SER E 5 176 ? -11.992 -53.779 -29.454 1.00 44.14  ? 176 SER G OG  1 
ATOM   7804 N N   . SER E 5 177 ? -15.340 -55.181 -30.671 1.00 45.14  ? 177 SER G N   1 
ATOM   7805 C CA  . SER E 5 177 ? -16.630 -54.808 -30.103 1.00 35.72  ? 177 SER G CA  1 
ATOM   7806 C C   . SER E 5 177 ? -16.816 -55.582 -28.808 1.00 37.06  ? 177 SER G C   1 
ATOM   7807 O O   . SER E 5 177 ? -16.739 -56.815 -28.801 1.00 34.61  ? 177 SER G O   1 
ATOM   7808 C CB  . SER E 5 177 ? -17.771 -55.098 -31.080 1.00 36.96  ? 177 SER G CB  1 
ATOM   7809 O OG  . SER E 5 177 ? -19.015 -54.676 -30.547 1.00 41.51  ? 177 SER G OG  1 
ATOM   7810 N N   . THR E 5 178 ? -17.060 -54.863 -27.717 1.00 24.01  ? 178 THR G N   1 
ATOM   7811 C CA  . THR E 5 178 ? -17.182 -55.460 -26.394 1.00 30.48  ? 178 THR G CA  1 
ATOM   7812 C C   . THR E 5 178 ? -18.617 -55.316 -25.909 1.00 35.81  ? 178 THR G C   1 
ATOM   7813 O O   . THR E 5 178 ? -19.101 -54.196 -25.716 1.00 30.86  ? 178 THR G O   1 
ATOM   7814 C CB  . THR E 5 178 ? -16.216 -54.808 -25.405 1.00 35.01  ? 178 THR G CB  1 
ATOM   7815 O OG1 . THR E 5 178 ? -14.887 -54.842 -25.938 1.00 40.71  ? 178 THR G OG1 1 
ATOM   7816 C CG2 . THR E 5 178 ? -16.240 -55.547 -24.075 1.00 26.93  ? 178 THR G CG2 1 
ATOM   7817 N N   . LEU E 5 179 ? -19.285 -56.447 -25.708 1.00 33.21  ? 179 LEU G N   1 
ATOM   7818 C CA  . LEU E 5 179 ? -20.629 -56.472 -25.147 1.00 27.59  ? 179 LEU G CA  1 
ATOM   7819 C C   . LEU E 5 179 ? -20.512 -56.687 -23.643 1.00 34.31  ? 179 LEU G C   1 
ATOM   7820 O O   . LEU E 5 179 ? -19.896 -57.663 -23.198 1.00 39.21  ? 179 LEU G O   1 
ATOM   7821 C CB  . LEU E 5 179 ? -21.458 -57.579 -25.800 1.00 28.55  ? 179 LEU G CB  1 
ATOM   7822 C CG  . LEU E 5 179 ? -22.981 -57.440 -25.882 1.00 32.89  ? 179 LEU G CG  1 
ATOM   7823 C CD1 . LEU E 5 179 ? -23.565 -58.569 -26.713 1.00 34.44  ? 179 LEU G CD1 1 
ATOM   7824 C CD2 . LEU E 5 179 ? -23.615 -57.425 -24.506 1.00 40.60  ? 179 LEU G CD2 1 
ATOM   7825 N N   . THR E 5 180 ? -21.097 -55.783 -22.863 1.00 26.05  ? 180 THR G N   1 
ATOM   7826 C CA  . THR E 5 180 ? -20.997 -55.815 -21.409 1.00 28.94  ? 180 THR G CA  1 
ATOM   7827 C C   . THR E 5 180 ? -22.363 -56.136 -20.818 1.00 36.81  ? 180 THR G C   1 
ATOM   7828 O O   . THR E 5 180 ? -23.344 -55.437 -21.094 1.00 37.60  ? 180 THR G O   1 
ATOM   7829 C CB  . THR E 5 180 ? -20.478 -54.484 -20.864 1.00 33.21  ? 180 THR G CB  1 
ATOM   7830 O OG1 . THR E 5 180 ? -19.156 -54.247 -21.362 1.00 49.35  ? 180 THR G OG1 1 
ATOM   7831 C CG2 . THR E 5 180 ? -20.445 -54.508 -19.344 1.00 35.46  ? 180 THR G CG2 1 
ATOM   7832 N N   . LEU E 5 181 ? -22.418 -57.188 -20.005 1.00 41.14  ? 181 LEU G N   1 
ATOM   7833 C CA  . LEU E 5 181 ? -23.643 -57.606 -19.342 1.00 43.79  ? 181 LEU G CA  1 
ATOM   7834 C C   . LEU E 5 181 ? -23.331 -57.983 -17.903 1.00 39.97  ? 181 LEU G C   1 
ATOM   7835 O O   . LEU E 5 181 ? -22.202 -58.350 -17.565 1.00 43.24  ? 181 LEU G O   1 
ATOM   7836 C CB  . LEU E 5 181 ? -24.302 -58.796 -20.055 1.00 31.03  ? 181 LEU G CB  1 
ATOM   7837 C CG  . LEU E 5 181 ? -25.031 -58.525 -21.369 1.00 41.28  ? 181 LEU G CG  1 
ATOM   7838 C CD1 . LEU E 5 181 ? -25.357 -59.834 -22.067 1.00 38.51  ? 181 LEU G CD1 1 
ATOM   7839 C CD2 . LEU E 5 181 ? -26.295 -57.723 -21.116 1.00 47.43  ? 181 LEU G CD2 1 
ATOM   7840 N N   . SER E 5 182 ? -24.349 -57.887 -17.054 1.00 41.05  ? 182 SER G N   1 
ATOM   7841 C CA  . SER E 5 182 ? -24.228 -58.409 -15.704 1.00 46.59  ? 182 SER G CA  1 
ATOM   7842 C C   . SER E 5 182 ? -24.216 -59.934 -15.741 1.00 48.28  ? 182 SER G C   1 
ATOM   7843 O O   . SER E 5 182 ? -24.584 -60.562 -16.738 1.00 46.96  ? 182 SER G O   1 
ATOM   7844 C CB  . SER E 5 182 ? -25.375 -57.911 -14.825 1.00 41.59  ? 182 SER G CB  1 
ATOM   7845 O OG  . SER E 5 182 ? -26.607 -58.490 -15.217 1.00 46.19  ? 182 SER G OG  1 
ATOM   7846 N N   . LYS E 5 183 ? -23.769 -60.533 -14.635 1.00 49.24  ? 183 LYS G N   1 
ATOM   7847 C CA  . LYS E 5 183 ? -23.740 -61.990 -14.554 1.00 53.08  ? 183 LYS G CA  1 
ATOM   7848 C C   . LYS E 5 183 ? -25.141 -62.577 -14.677 1.00 47.67  ? 183 LYS G C   1 
ATOM   7849 O O   . LYS E 5 183 ? -25.344 -63.574 -15.381 1.00 32.35  ? 183 LYS G O   1 
ATOM   7850 C CB  . LYS E 5 183 ? -23.089 -62.432 -13.246 1.00 57.38  ? 183 LYS G CB  1 
ATOM   7851 C CG  . LYS E 5 183 ? -23.314 -63.897 -12.914 1.00 49.33  ? 183 LYS G CG  1 
ATOM   7852 C CD  . LYS E 5 183 ? -23.350 -64.106 -11.410 1.00 56.49  ? 183 LYS G CD  1 
ATOM   7853 C CE  . LYS E 5 183 ? -24.391 -63.203 -10.750 1.00 60.74  ? 183 LYS G CE  1 
ATOM   7854 N NZ  . LYS E 5 183 ? -25.796 -63.619 -11.040 1.00 60.67  ? 183 LYS G NZ  1 
ATOM   7855 N N   . ALA E 5 184 ? -26.121 -61.971 -14.002 1.00 46.95  ? 184 ALA G N   1 
ATOM   7856 C CA  . ALA E 5 184 ? -27.490 -62.471 -14.076 1.00 44.51  ? 184 ALA G CA  1 
ATOM   7857 C C   . ALA E 5 184 ? -28.040 -62.376 -15.494 1.00 47.04  ? 184 ALA G C   1 
ATOM   7858 O O   . ALA E 5 184 ? -28.692 -63.308 -15.979 1.00 48.54  ? 184 ALA G O   1 
ATOM   7859 C CB  . ALA E 5 184 ? -28.381 -61.704 -13.100 1.00 48.75  ? 184 ALA G CB  1 
ATOM   7860 N N   . ASP E 5 185 ? -27.785 -61.256 -16.175 1.00 46.69  ? 185 ASP G N   1 
ATOM   7861 C CA  . ASP E 5 185 ? -28.259 -61.098 -17.546 1.00 38.00  ? 185 ASP G CA  1 
ATOM   7862 C C   . ASP E 5 185 ? -27.496 -61.991 -18.515 1.00 35.24  ? 185 ASP G C   1 
ATOM   7863 O O   . ASP E 5 185 ? -28.063 -62.437 -19.520 1.00 37.56  ? 185 ASP G O   1 
ATOM   7864 C CB  . ASP E 5 185 ? -28.150 -59.635 -17.970 1.00 43.93  ? 185 ASP G CB  1 
ATOM   7865 C CG  . ASP E 5 185 ? -29.166 -58.752 -17.277 1.00 61.91  ? 185 ASP G CG  1 
ATOM   7866 O OD1 . ASP E 5 185 ? -30.360 -58.822 -17.638 1.00 69.92  ? 185 ASP G OD1 1 
ATOM   7867 O OD2 . ASP E 5 185 ? -28.776 -58.002 -16.357 1.00 66.30  ? 185 ASP G OD2 1 
ATOM   7868 N N   . TYR E 5 186 ? -26.218 -62.260 -18.237 1.00 38.93  ? 186 TYR G N   1 
ATOM   7869 C CA  . TYR E 5 186 ? -25.428 -63.106 -19.127 1.00 44.18  ? 186 TYR G CA  1 
ATOM   7870 C C   . TYR E 5 186 ? -25.982 -64.524 -19.186 1.00 39.57  ? 186 TYR G C   1 
ATOM   7871 O O   . TYR E 5 186 ? -25.993 -65.150 -20.252 1.00 39.40  ? 186 TYR G O   1 
ATOM   7872 C CB  . TYR E 5 186 ? -23.965 -63.120 -18.681 1.00 36.94  ? 186 TYR G CB  1 
ATOM   7873 C CG  . TYR E 5 186 ? -23.105 -64.105 -19.443 1.00 28.81  ? 186 TYR G CG  1 
ATOM   7874 C CD1 . TYR E 5 186 ? -22.820 -63.911 -20.788 1.00 36.23  ? 186 TYR G CD1 1 
ATOM   7875 C CD2 . TYR E 5 186 ? -22.574 -65.224 -18.816 1.00 36.71  ? 186 TYR G CD2 1 
ATOM   7876 C CE1 . TYR E 5 186 ? -22.034 -64.808 -21.489 1.00 37.16  ? 186 TYR G CE1 1 
ATOM   7877 C CE2 . TYR E 5 186 ? -21.786 -66.125 -19.508 1.00 33.22  ? 186 TYR G CE2 1 
ATOM   7878 C CZ  . TYR E 5 186 ? -21.520 -65.913 -20.844 1.00 39.28  ? 186 TYR G CZ  1 
ATOM   7879 O OH  . TYR E 5 186 ? -20.737 -66.809 -21.536 1.00 38.66  ? 186 TYR G OH  1 
ATOM   7880 N N   . GLU E 5 187 ? -26.445 -65.047 -18.052 1.00 43.74  ? 187 GLU G N   1 
ATOM   7881 C CA  . GLU E 5 187 ? -26.942 -66.415 -17.979 1.00 51.98  ? 187 GLU G CA  1 
ATOM   7882 C C   . GLU E 5 187 ? -28.400 -66.546 -18.399 1.00 47.51  ? 187 GLU G C   1 
ATOM   7883 O O   . GLU E 5 187 ? -28.932 -67.662 -18.388 1.00 54.84  ? 187 GLU G O   1 
ATOM   7884 C CB  . GLU E 5 187 ? -26.752 -66.959 -16.560 1.00 47.25  ? 187 GLU G CB  1 
ATOM   7885 C CG  . GLU E 5 187 ? -25.298 -67.258 -16.219 1.00 59.86  ? 187 GLU G CG  1 
ATOM   7886 C CD  . GLU E 5 187 ? -25.055 -67.382 -14.728 1.00 68.84  ? 187 GLU G CD  1 
ATOM   7887 O OE1 . GLU E 5 187 ? -25.894 -66.892 -13.943 1.00 70.56  ? 187 GLU G OE1 1 
ATOM   7888 O OE2 . GLU E 5 187 ? -24.020 -67.966 -14.341 1.00 68.22  ? 187 GLU G OE2 1 
ATOM   7889 N N   . LYS E 5 188 ? -29.054 -65.446 -18.769 1.00 42.17  ? 188 LYS G N   1 
ATOM   7890 C CA  . LYS E 5 188 ? -30.414 -65.490 -19.288 1.00 39.43  ? 188 LYS G CA  1 
ATOM   7891 C C   . LYS E 5 188 ? -30.478 -65.932 -20.743 1.00 42.65  ? 188 LYS G C   1 
ATOM   7892 O O   . LYS E 5 188 ? -31.581 -66.106 -21.272 1.00 42.08  ? 188 LYS G O   1 
ATOM   7893 C CB  . LYS E 5 188 ? -31.078 -64.117 -19.144 1.00 34.61  ? 188 LYS G CB  1 
ATOM   7894 C CG  . LYS E 5 188 ? -31.374 -63.719 -17.712 1.00 26.02  ? 188 LYS G CG  1 
ATOM   7895 C CD  . LYS E 5 188 ? -31.865 -62.285 -17.629 1.00 47.45  ? 188 LYS G CD  1 
ATOM   7896 C CE  . LYS E 5 188 ? -32.389 -61.970 -16.239 1.00 43.41  ? 188 LYS G CE  1 
ATOM   7897 N NZ  . LYS E 5 188 ? -32.510 -60.505 -16.009 1.00 44.77  ? 188 LYS G NZ  1 
ATOM   7898 N N   . HIS E 5 189 ? -29.334 -66.117 -21.399 1.00 37.47  ? 189 HIS G N   1 
ATOM   7899 C CA  . HIS E 5 189 ? -29.290 -66.458 -22.811 1.00 34.66  ? 189 HIS G CA  1 
ATOM   7900 C C   . HIS E 5 189 ? -28.292 -67.586 -23.039 1.00 40.68  ? 189 HIS G C   1 
ATOM   7901 O O   . HIS E 5 189 ? -27.385 -67.816 -22.235 1.00 43.23  ? 189 HIS G O   1 
ATOM   7902 C CB  . HIS E 5 189 ? -28.912 -65.245 -23.666 1.00 36.54  ? 189 HIS G CB  1 
ATOM   7903 C CG  . HIS E 5 189 ? -29.651 -63.993 -23.306 1.00 39.42  ? 189 HIS G CG  1 
ATOM   7904 N ND1 . HIS E 5 189 ? -29.116 -63.024 -22.484 1.00 33.49  ? 189 HIS G ND1 1 
ATOM   7905 C CD2 . HIS E 5 189 ? -30.882 -63.552 -23.655 1.00 50.03  ? 189 HIS G CD2 1 
ATOM   7906 C CE1 . HIS E 5 189 ? -29.986 -62.040 -22.343 1.00 36.69  ? 189 HIS G CE1 1 
ATOM   7907 N NE2 . HIS E 5 189 ? -31.066 -62.335 -23.043 1.00 51.48  ? 189 HIS G NE2 1 
ATOM   7908 N N   . LYS E 5 190 ? -28.470 -68.285 -24.159 1.00 40.05  ? 190 LYS G N   1 
ATOM   7909 C CA  . LYS E 5 190 ? -27.682 -69.466 -24.489 1.00 42.32  ? 190 LYS G CA  1 
ATOM   7910 C C   . LYS E 5 190 ? -26.641 -69.191 -25.567 1.00 47.12  ? 190 LYS G C   1 
ATOM   7911 O O   . LYS E 5 190 ? -25.449 -69.429 -25.352 1.00 53.59  ? 190 LYS G O   1 
ATOM   7912 C CB  . LYS E 5 190 ? -28.621 -70.598 -24.930 1.00 45.72  ? 190 LYS G CB  1 
ATOM   7913 C CG  . LYS E 5 190 ? -27.956 -71.714 -25.722 1.00 62.51  ? 190 LYS G CG  1 
ATOM   7914 C CD  . LYS E 5 190 ? -27.394 -72.804 -24.826 1.00 68.61  ? 190 LYS G CD  1 
ATOM   7915 C CE  . LYS E 5 190 ? -27.107 -74.061 -25.636 1.00 62.12  ? 190 LYS G CE  1 
ATOM   7916 N NZ  . LYS E 5 190 ? -26.560 -75.177 -24.816 1.00 60.68  ? 190 LYS G NZ  1 
ATOM   7917 N N   . VAL E 5 191 ? -27.059 -68.686 -26.724 1.00 40.67  ? 191 VAL G N   1 
ATOM   7918 C CA  . VAL E 5 191 ? -26.180 -68.523 -27.876 1.00 39.49  ? 191 VAL G CA  1 
ATOM   7919 C C   . VAL E 5 191 ? -25.828 -67.049 -28.021 1.00 46.61  ? 191 VAL G C   1 
ATOM   7920 O O   . VAL E 5 191 ? -26.716 -66.198 -28.154 1.00 44.64  ? 191 VAL G O   1 
ATOM   7921 C CB  . VAL E 5 191 ? -26.833 -69.059 -29.160 1.00 34.43  ? 191 VAL G CB  1 
ATOM   7922 C CG1 . VAL E 5 191 ? -26.029 -68.634 -30.379 1.00 34.15  ? 191 VAL G CG1 1 
ATOM   7923 C CG2 . VAL E 5 191 ? -26.952 -70.572 -29.102 1.00 52.02  ? 191 VAL G CG2 1 
ATOM   7924 N N   . TYR E 5 192 ? -24.532 -66.752 -28.001 1.00 38.08  ? 192 TYR G N   1 
ATOM   7925 C CA  . TYR E 5 192 ? -24.011 -65.415 -28.257 1.00 38.35  ? 192 TYR G CA  1 
ATOM   7926 C C   . TYR E 5 192 ? -23.299 -65.434 -29.601 1.00 43.93  ? 192 TYR G C   1 
ATOM   7927 O O   . TYR E 5 192 ? -22.381 -66.235 -29.807 1.00 42.85  ? 192 TYR G O   1 
ATOM   7928 C CB  . TYR E 5 192 ? -23.059 -64.974 -27.146 1.00 32.34  ? 192 TYR G CB  1 
ATOM   7929 C CG  . TYR E 5 192 ? -23.747 -64.685 -25.835 1.00 40.01  ? 192 TYR G CG  1 
ATOM   7930 C CD1 . TYR E 5 192 ? -24.105 -65.714 -24.973 1.00 36.94  ? 192 TYR G CD1 1 
ATOM   7931 C CD2 . TYR E 5 192 ? -24.037 -63.382 -25.457 1.00 39.34  ? 192 TYR G CD2 1 
ATOM   7932 C CE1 . TYR E 5 192 ? -24.735 -65.453 -23.774 1.00 29.84  ? 192 TYR G CE1 1 
ATOM   7933 C CE2 . TYR E 5 192 ? -24.666 -63.110 -24.259 1.00 37.81  ? 192 TYR G CE2 1 
ATOM   7934 C CZ  . TYR E 5 192 ? -25.013 -64.149 -23.422 1.00 42.55  ? 192 TYR G CZ  1 
ATOM   7935 O OH  . TYR E 5 192 ? -25.641 -63.882 -22.229 1.00 38.56  ? 192 TYR G OH  1 
ATOM   7936 N N   . ALA E 5 193 ? -23.715 -64.551 -30.508 1.00 34.63  ? 193 ALA G N   1 
ATOM   7937 C CA  . ALA E 5 193 ? -23.207 -64.536 -31.871 1.00 32.01  ? 193 ALA G CA  1 
ATOM   7938 C C   . ALA E 5 193 ? -22.751 -63.136 -32.252 1.00 35.73  ? 193 ALA G C   1 
ATOM   7939 O O   . ALA E 5 193 ? -23.271 -62.134 -31.753 1.00 40.09  ? 193 ALA G O   1 
ATOM   7940 C CB  . ALA E 5 193 ? -24.266 -65.022 -32.869 1.00 33.85  ? 193 ALA G CB  1 
ATOM   7941 N N   . CYS E 5 194 ? -21.768 -63.083 -33.149 1.00 40.96  ? 194 CYS G N   1 
ATOM   7942 C CA  . CYS E 5 194 ? -21.257 -61.834 -33.700 1.00 36.76  ? 194 CYS G CA  1 
ATOM   7943 C C   . CYS E 5 194 ? -21.337 -61.917 -35.217 1.00 31.40  ? 194 CYS G C   1 
ATOM   7944 O O   . CYS E 5 194 ? -20.750 -62.821 -35.821 1.00 35.81  ? 194 CYS G O   1 
ATOM   7945 C CB  . CYS E 5 194 ? -19.816 -61.582 -33.247 1.00 37.68  ? 194 CYS G CB  1 
ATOM   7946 S SG  . CYS E 5 194 ? -19.058 -60.079 -33.907 1.00 83.32  ? 194 CYS G SG  1 
ATOM   7947 N N   . GLU E 5 195 ? -22.059 -60.983 -35.828 1.00 31.62  ? 195 GLU G N   1 
ATOM   7948 C CA  . GLU E 5 195 ? -22.218 -60.935 -37.276 1.00 37.24  ? 195 GLU G CA  1 
ATOM   7949 C C   . GLU E 5 195 ? -21.473 -59.728 -37.827 1.00 35.44  ? 195 GLU G C   1 
ATOM   7950 O O   . GLU E 5 195 ? -21.681 -58.598 -37.369 1.00 34.31  ? 195 GLU G O   1 
ATOM   7951 C CB  . GLU E 5 195 ? -23.695 -60.878 -37.672 1.00 38.23  ? 195 GLU G CB  1 
ATOM   7952 C CG  . GLU E 5 195 ? -24.398 -62.225 -37.616 1.00 64.66  ? 195 GLU G CG  1 
ATOM   7953 C CD  . GLU E 5 195 ? -25.690 -62.245 -38.410 1.00 69.80  ? 195 GLU G CD  1 
ATOM   7954 O OE1 . GLU E 5 195 ? -26.013 -61.221 -39.048 1.00 64.45  ? 195 GLU G OE1 1 
ATOM   7955 O OE2 . GLU E 5 195 ? -26.380 -63.286 -38.400 1.00 61.26  ? 195 GLU G OE2 1 
ATOM   7956 N N   . VAL E 5 196 ? -20.614 -59.971 -38.813 1.00 39.24  ? 196 VAL G N   1 
ATOM   7957 C CA  . VAL E 5 196 ? -19.738 -58.954 -39.378 1.00 42.37  ? 196 VAL G CA  1 
ATOM   7958 C C   . VAL E 5 196 ? -20.100 -58.764 -40.843 1.00 41.76  ? 196 VAL G C   1 
ATOM   7959 O O   . VAL E 5 196 ? -20.116 -59.731 -41.614 1.00 47.71  ? 196 VAL G O   1 
ATOM   7960 C CB  . VAL E 5 196 ? -18.256 -59.340 -39.227 1.00 48.12  ? 196 VAL G CB  1 
ATOM   7961 C CG1 . VAL E 5 196 ? -17.364 -58.302 -39.887 1.00 44.12  ? 196 VAL G CG1 1 
ATOM   7962 C CG2 . VAL E 5 196 ? -17.900 -59.507 -37.757 1.00 39.40  ? 196 VAL G CG2 1 
ATOM   7963 N N   . THR E 5 197 ? -20.388 -57.523 -41.223 1.00 45.20  ? 197 THR G N   1 
ATOM   7964 C CA  . THR E 5 197 ? -20.664 -57.157 -42.608 1.00 53.07  ? 197 THR G CA  1 
ATOM   7965 C C   . THR E 5 197 ? -19.527 -56.275 -43.106 1.00 60.01  ? 197 THR G C   1 
ATOM   7966 O O   . THR E 5 197 ? -19.237 -55.234 -42.507 1.00 61.94  ? 197 THR G O   1 
ATOM   7967 C CB  . THR E 5 197 ? -22.003 -56.430 -42.733 1.00 43.89  ? 197 THR G CB  1 
ATOM   7968 O OG1 . THR E 5 197 ? -23.070 -57.325 -42.394 1.00 55.95  ? 197 THR G OG1 1 
ATOM   7969 C CG2 . THR E 5 197 ? -22.203 -55.926 -44.154 1.00 51.25  ? 197 THR G CG2 1 
ATOM   7970 N N   . HIS E 5 198 ? -18.890 -56.689 -44.199 1.00 72.80  ? 198 HIS G N   1 
ATOM   7971 C CA  . HIS E 5 198 ? -17.741 -55.967 -44.725 1.00 68.73  ? 198 HIS G CA  1 
ATOM   7972 C C   . HIS E 5 198 ? -17.728 -56.086 -46.242 1.00 68.47  ? 198 HIS G C   1 
ATOM   7973 O O   . HIS E 5 198 ? -18.334 -56.993 -46.820 1.00 71.12  ? 198 HIS G O   1 
ATOM   7974 C CB  . HIS E 5 198 ? -16.430 -56.491 -44.122 1.00 65.18  ? 198 HIS G CB  1 
ATOM   7975 C CG  . HIS E 5 198 ? -15.233 -55.649 -44.442 1.00 67.31  ? 198 HIS G CG  1 
ATOM   7976 N ND1 . HIS E 5 198 ? -14.246 -56.059 -45.313 1.00 66.66  ? 198 HIS G ND1 1 
ATOM   7977 C CD2 . HIS E 5 198 ? -14.863 -54.422 -44.005 1.00 62.14  ? 198 HIS G CD2 1 
ATOM   7978 C CE1 . HIS E 5 198 ? -13.320 -55.120 -45.399 1.00 58.77  ? 198 HIS G CE1 1 
ATOM   7979 N NE2 . HIS E 5 198 ? -13.671 -54.116 -44.615 1.00 53.70  ? 198 HIS G NE2 1 
ATOM   7980 N N   . GLN E 5 199 ? -17.027 -55.146 -46.880 1.00 61.63  ? 199 GLN G N   1 
ATOM   7981 C CA  . GLN E 5 199 ? -16.928 -55.146 -48.336 1.00 63.95  ? 199 GLN G CA  1 
ATOM   7982 C C   . GLN E 5 199 ? -16.213 -56.392 -48.845 1.00 60.05  ? 199 GLN G C   1 
ATOM   7983 O O   . GLN E 5 199 ? -16.594 -56.959 -49.876 1.00 64.85  ? 199 GLN G O   1 
ATOM   7984 C CB  . GLN E 5 199 ? -16.207 -53.884 -48.809 1.00 64.18  ? 199 GLN G CB  1 
ATOM   7985 C CG  . GLN E 5 199 ? -15.989 -53.819 -50.311 1.00 68.30  ? 199 GLN G CG  1 
ATOM   7986 C CD  . GLN E 5 199 ? -15.082 -52.676 -50.716 1.00 70.50  ? 199 GLN G CD  1 
ATOM   7987 O OE1 . GLN E 5 199 ? -14.705 -51.846 -49.890 1.00 67.80  ? 199 GLN G OE1 1 
ATOM   7988 N NE2 . GLN E 5 199 ? -14.721 -52.631 -51.994 1.00 73.07  ? 199 GLN G NE2 1 
ATOM   7989 N N   . GLY E 5 200 ? -15.179 -56.836 -48.134 1.00 53.69  ? 200 GLY G N   1 
ATOM   7990 C CA  . GLY E 5 200 ? -14.388 -57.975 -48.551 1.00 58.21  ? 200 GLY G CA  1 
ATOM   7991 C C   . GLY E 5 200 ? -15.012 -59.329 -48.315 1.00 69.49  ? 200 GLY G C   1 
ATOM   7992 O O   . GLY E 5 200 ? -14.364 -60.350 -48.558 1.00 62.47  ? 200 GLY G O   1 
ATOM   7993 N N   . LEU E 5 201 ? -16.254 -59.371 -47.844 1.00 74.70  ? 201 LEU G N   1 
ATOM   7994 C CA  . LEU E 5 201 ? -16.961 -60.615 -47.575 1.00 71.41  ? 201 LEU G CA  1 
ATOM   7995 C C   . LEU E 5 201 ? -18.147 -60.738 -48.523 1.00 75.07  ? 201 LEU G C   1 
ATOM   7996 O O   . LEU E 5 201 ? -18.913 -59.783 -48.691 1.00 63.47  ? 201 LEU G O   1 
ATOM   7997 C CB  . LEU E 5 201 ? -17.435 -60.665 -46.122 1.00 61.41  ? 201 LEU G CB  1 
ATOM   7998 C CG  . LEU E 5 201 ? -16.336 -60.618 -45.061 1.00 59.09  ? 201 LEU G CG  1 
ATOM   7999 C CD1 . LEU E 5 201 ? -16.886 -60.086 -43.750 1.00 60.62  ? 201 LEU G CD1 1 
ATOM   8000 C CD2 . LEU E 5 201 ? -15.733 -61.998 -44.864 1.00 61.47  ? 201 LEU G CD2 1 
ATOM   8001 N N   . SER E 5 202 ? -18.287 -61.910 -49.147 1.00 80.70  ? 202 SER G N   1 
ATOM   8002 C CA  . SER E 5 202 ? -19.428 -62.145 -50.026 1.00 75.32  ? 202 SER G CA  1 
ATOM   8003 C C   . SER E 5 202 ? -20.735 -62.117 -49.246 1.00 74.50  ? 202 SER G C   1 
ATOM   8004 O O   . SER E 5 202 ? -21.719 -61.509 -49.685 1.00 72.72  ? 202 SER G O   1 
ATOM   8005 C CB  . SER E 5 202 ? -19.264 -63.482 -50.750 1.00 76.76  ? 202 SER G CB  1 
ATOM   8006 O OG  . SER E 5 202 ? -18.026 -63.543 -51.436 1.00 81.39  ? 202 SER G OG  1 
ATOM   8007 N N   . SER E 5 203 ? -20.762 -62.763 -48.090 1.00 74.48  ? 203 SER G N   1 
ATOM   8008 C CA  . SER E 5 203 ? -21.903 -62.793 -47.191 1.00 68.40  ? 203 SER G CA  1 
ATOM   8009 C C   . SER E 5 203 ? -21.416 -62.518 -45.779 1.00 65.61  ? 203 SER G C   1 
ATOM   8010 O O   . SER E 5 203 ? -20.238 -62.728 -45.470 1.00 64.84  ? 203 SER G O   1 
ATOM   8011 C CB  . SER E 5 203 ? -22.621 -64.151 -47.248 1.00 56.95  ? 203 SER G CB  1 
ATOM   8012 O OG  . SER E 5 203 ? -21.774 -65.194 -46.801 1.00 71.75  ? 203 SER G OG  1 
ATOM   8013 N N   . PRO E 5 204 ? -22.291 -62.027 -44.901 1.00 58.04  ? 204 PRO G N   1 
ATOM   8014 C CA  . PRO E 5 204 ? -21.871 -61.758 -43.520 1.00 52.48  ? 204 PRO G CA  1 
ATOM   8015 C C   . PRO E 5 204 ? -21.363 -63.017 -42.831 1.00 57.97  ? 204 PRO G C   1 
ATOM   8016 O O   . PRO E 5 204 ? -21.880 -64.117 -43.040 1.00 56.72  ? 204 PRO G O   1 
ATOM   8017 C CB  . PRO E 5 204 ? -23.149 -61.230 -42.859 1.00 55.95  ? 204 PRO G CB  1 
ATOM   8018 C CG  . PRO E 5 204 ? -23.941 -60.661 -43.986 1.00 47.30  ? 204 PRO G CG  1 
ATOM   8019 C CD  . PRO E 5 204 ? -23.661 -61.551 -45.162 1.00 57.88  ? 204 PRO G CD  1 
ATOM   8020 N N   . VAL E 5 205 ? -20.336 -62.843 -42.004 1.00 52.96  ? 205 VAL G N   1 
ATOM   8021 C CA  . VAL E 5 205 ? -19.701 -63.940 -41.282 1.00 61.95  ? 205 VAL G CA  1 
ATOM   8022 C C   . VAL E 5 205 ? -20.178 -63.915 -39.839 1.00 52.49  ? 205 VAL G C   1 
ATOM   8023 O O   . VAL E 5 205 ? -20.116 -62.874 -39.172 1.00 53.90  ? 205 VAL G O   1 
ATOM   8024 C CB  . VAL E 5 205 ? -18.167 -63.845 -41.360 1.00 60.02  ? 205 VAL G CB  1 
ATOM   8025 C CG1 . VAL E 5 205 ? -17.522 -64.757 -40.328 1.00 46.55  ? 205 VAL G CG1 1 
ATOM   8026 C CG2 . VAL E 5 205 ? -17.693 -64.207 -42.753 1.00 63.17  ? 205 VAL G CG2 1 
ATOM   8027 N N   . THR E 5 206 ? -20.655 -65.058 -39.356 1.00 51.77  ? 206 THR G N   1 
ATOM   8028 C CA  . THR E 5 206 ? -21.173 -65.188 -38.003 1.00 50.68  ? 206 THR G CA  1 
ATOM   8029 C C   . THR E 5 206 ? -20.265 -66.101 -37.193 1.00 45.92  ? 206 THR G C   1 
ATOM   8030 O O   . THR E 5 206 ? -19.997 -67.237 -37.597 1.00 56.52  ? 206 THR G O   1 
ATOM   8031 C CB  . THR E 5 206 ? -22.599 -65.744 -38.010 1.00 50.76  ? 206 THR G CB  1 
ATOM   8032 O OG1 . THR E 5 206 ? -23.389 -65.027 -38.966 1.00 56.22  ? 206 THR G OG1 1 
ATOM   8033 C CG2 . THR E 5 206 ? -23.229 -65.602 -36.634 1.00 37.74  ? 206 THR G CG2 1 
ATOM   8034 N N   . LYS E 5 207 ? -19.793 -65.601 -36.054 1.00 43.34  ? 207 LYS G N   1 
ATOM   8035 C CA  . LYS E 5 207 ? -19.029 -66.389 -35.098 1.00 35.03  ? 207 LYS G CA  1 
ATOM   8036 C C   . LYS E 5 207 ? -19.783 -66.408 -33.778 1.00 38.32  ? 207 LYS G C   1 
ATOM   8037 O O   . LYS E 5 207 ? -20.140 -65.350 -33.248 1.00 44.87  ? 207 LYS G O   1 
ATOM   8038 C CB  . LYS E 5 207 ? -17.621 -65.821 -34.913 1.00 46.90  ? 207 LYS G CB  1 
ATOM   8039 C CG  . LYS E 5 207 ? -16.726 -66.034 -36.118 1.00 55.00  ? 207 LYS G CG  1 
ATOM   8040 C CD  . LYS E 5 207 ? -16.563 -67.515 -36.414 1.00 57.17  ? 207 LYS G CD  1 
ATOM   8041 C CE  . LYS E 5 207 ? -15.798 -67.740 -37.705 1.00 55.20  ? 207 LYS G CE  1 
ATOM   8042 N NZ  . LYS E 5 207 ? -15.224 -69.112 -37.767 1.00 56.80  ? 207 LYS G NZ  1 
ATOM   8043 N N   . SER E 5 208 ? -20.026 -67.606 -33.251 1.00 46.87  ? 208 SER G N   1 
ATOM   8044 C CA  . SER E 5 208 ? -20.900 -67.768 -32.101 1.00 42.83  ? 208 SER G CA  1 
ATOM   8045 C C   . SER E 5 208 ? -20.347 -68.834 -31.166 1.00 41.41  ? 208 SER G C   1 
ATOM   8046 O O   . SER E 5 208 ? -19.553 -69.690 -31.561 1.00 51.74  ? 208 SER G O   1 
ATOM   8047 C CB  . SER E 5 208 ? -22.326 -68.138 -32.532 1.00 42.48  ? 208 SER G CB  1 
ATOM   8048 O OG  . SER E 5 208 ? -22.330 -69.323 -33.310 1.00 44.64  ? 208 SER G OG  1 
ATOM   8049 N N   . PHE E 5 209 ? -20.783 -68.762 -29.910 1.00 42.99  ? 209 PHE G N   1 
ATOM   8050 C CA  . PHE E 5 209 ? -20.483 -69.778 -28.914 1.00 37.27  ? 209 PHE G CA  1 
ATOM   8051 C C   . PHE E 5 209 ? -21.721 -70.000 -28.058 1.00 45.64  ? 209 PHE G C   1 
ATOM   8052 O O   . PHE E 5 209 ? -22.586 -69.128 -27.945 1.00 45.23  ? 209 PHE G O   1 
ATOM   8053 C CB  . PHE E 5 209 ? -19.285 -69.385 -28.035 1.00 41.63  ? 209 PHE G CB  1 
ATOM   8054 C CG  . PHE E 5 209 ? -19.541 -68.196 -27.149 1.00 40.62  ? 209 PHE G CG  1 
ATOM   8055 C CD1 . PHE E 5 209 ? -19.284 -66.912 -27.599 1.00 34.68  ? 209 PHE G CD1 1 
ATOM   8056 C CD2 . PHE E 5 209 ? -20.027 -68.364 -25.861 1.00 39.95  ? 209 PHE G CD2 1 
ATOM   8057 C CE1 . PHE E 5 209 ? -19.514 -65.817 -26.785 1.00 38.53  ? 209 PHE G CE1 1 
ATOM   8058 C CE2 . PHE E 5 209 ? -20.262 -67.274 -25.044 1.00 38.00  ? 209 PHE G CE2 1 
ATOM   8059 C CZ  . PHE E 5 209 ? -20.003 -65.999 -25.507 1.00 43.85  ? 209 PHE G CZ  1 
ATOM   8060 N N   . ASN E 5 210 ? -21.799 -71.180 -27.452 1.00 50.49  ? 210 ASN G N   1 
ATOM   8061 C CA  . ASN E 5 210 ? -22.889 -71.529 -26.551 1.00 46.50  ? 210 ASN G CA  1 
ATOM   8062 C C   . ASN E 5 210 ? -22.386 -71.490 -25.116 1.00 49.54  ? 210 ASN G C   1 
ATOM   8063 O O   . ASN E 5 210 ? -21.367 -72.111 -24.793 1.00 65.57  ? 210 ASN G O   1 
ATOM   8064 C CB  . ASN E 5 210 ? -23.464 -72.908 -26.883 1.00 49.56  ? 210 ASN G CB  1 
ATOM   8065 C CG  . ASN E 5 210 ? -24.192 -72.931 -28.214 1.00 61.73  ? 210 ASN G CG  1 
ATOM   8066 O OD1 . ASN E 5 210 ? -23.803 -72.244 -29.159 1.00 57.54  ? 210 ASN G OD1 1 
ATOM   8067 N ND2 . ASN E 5 210 ? -25.261 -73.715 -28.292 1.00 69.70  ? 210 ASN G ND2 1 
ATOM   8068 N N   . ARG E 5 211 ? -23.097 -70.756 -24.266 1.00 42.60  ? 211 ARG G N   1 
ATOM   8069 C CA  . ARG E 5 211 ? -22.719 -70.593 -22.867 1.00 42.73  ? 211 ARG G CA  1 
ATOM   8070 C C   . ARG E 5 211 ? -22.719 -71.925 -22.125 1.00 56.76  ? 211 ARG G C   1 
ATOM   8071 O O   . ARG E 5 211 ? -23.753 -72.580 -22.009 1.00 67.03  ? 211 ARG G O   1 
ATOM   8072 C CB  . ARG E 5 211 ? -23.665 -69.609 -22.178 1.00 33.78  ? 211 ARG G CB  1 
ATOM   8073 C CG  . ARG E 5 211 ? -23.406 -69.426 -20.695 1.00 51.50  ? 211 ARG G CG  1 
ATOM   8074 C CD  . ARG E 5 211 ? -24.399 -68.451 -20.085 1.00 46.90  ? 211 ARG G CD  1 
ATOM   8075 N NE  . ARG E 5 211 ? -25.777 -68.882 -20.285 1.00 52.94  ? 211 ARG G NE  1 
ATOM   8076 C CZ  . ARG E 5 211 ? -26.446 -69.664 -19.449 1.00 57.08  ? 211 ARG G CZ  1 
ATOM   8077 N NH1 . ARG E 5 211 ? -25.892 -70.122 -18.339 1.00 66.21  ? 211 ARG G NH1 1 
ATOM   8078 N NH2 . ARG E 5 211 ? -27.703 -69.994 -19.734 1.00 43.90  ? 211 ARG G NH2 1 
HETATM 8079 C C1  . NAG F 6 .   ? 6.638   18.130  -42.396 1.00 35.94  ? 1   NAG B C1  1 
HETATM 8080 C C2  . NAG F 6 .   ? 6.696   19.266  -41.364 1.00 30.56  ? 1   NAG B C2  1 
HETATM 8081 C C3  . NAG F 6 .   ? 5.308   19.872  -41.144 1.00 31.97  ? 1   NAG B C3  1 
HETATM 8082 C C4  . NAG F 6 .   ? 4.570   20.163  -42.449 1.00 39.88  ? 1   NAG B C4  1 
HETATM 8083 C C5  . NAG F 6 .   ? 4.649   18.941  -43.369 1.00 43.28  ? 1   NAG B C5  1 
HETATM 8084 C C6  . NAG F 6 .   ? 4.006   19.143  -44.724 1.00 44.75  ? 1   NAG B C6  1 
HETATM 8085 C C7  . NAG F 6 .   ? 7.966   19.502  -39.252 1.00 34.56  ? 1   NAG B C7  1 
HETATM 8086 C C8  . NAG F 6 .   ? 8.376   18.769  -37.998 1.00 32.11  ? 1   NAG B C8  1 
HETATM 8087 N N2  . NAG F 6 .   ? 7.212   18.786  -40.108 1.00 31.13  ? 1   NAG B N2  1 
HETATM 8088 O O3  . NAG F 6 .   ? 5.469   21.035  -40.374 1.00 40.34  ? 1   NAG B O3  1 
HETATM 8089 O O4  . NAG F 6 .   ? 3.234   20.440  -42.096 1.00 44.03  ? 1   NAG B O4  1 
HETATM 8090 O O5  . NAG F 6 .   ? 6.004   18.596  -43.563 1.00 42.65  ? 1   NAG B O5  1 
HETATM 8091 O O6  . NAG F 6 .   ? 3.766   17.895  -45.332 1.00 35.17  ? 1   NAG B O6  1 
HETATM 8092 O O7  . NAG F 6 .   ? 8.306   20.658  -39.453 1.00 29.38  ? 1   NAG B O7  1 
HETATM 8093 C C1  . NAG F 6 .   ? 2.886   21.805  -42.417 1.00 36.12  ? 2   NAG B C1  1 
HETATM 8094 C C2  . NAG F 6 .   ? 1.353   21.894  -42.470 1.00 46.38  ? 2   NAG B C2  1 
HETATM 8095 C C3  . NAG F 6 .   ? 0.922   23.327  -42.769 1.00 50.52  ? 2   NAG B C3  1 
HETATM 8096 C C4  . NAG F 6 .   ? 1.556   24.302  -41.782 1.00 63.34  ? 2   NAG B C4  1 
HETATM 8097 C C5  . NAG F 6 .   ? 3.071   24.067  -41.714 1.00 62.27  ? 2   NAG B C5  1 
HETATM 8098 C C6  . NAG F 6 .   ? 3.762   24.920  -40.672 1.00 62.73  ? 2   NAG B C6  1 
HETATM 8099 C C7  . NAG F 6 .   ? 0.174   19.840  -43.142 1.00 52.37  ? 2   NAG B C7  1 
HETATM 8100 C C8  . NAG F 6 .   ? -0.313  19.043  -44.327 1.00 37.34  ? 2   NAG B C8  1 
HETATM 8101 N N2  . NAG F 6 .   ? 0.813   20.985  -43.446 1.00 47.98  ? 2   NAG B N2  1 
HETATM 8102 O O3  . NAG F 6 .   ? -0.480  23.366  -42.725 1.00 63.30  ? 2   NAG B O3  1 
HETATM 8103 O O4  . NAG F 6 .   ? 1.267   25.603  -42.244 1.00 76.03  ? 2   NAG B O4  1 
HETATM 8104 O O5  . NAG F 6 .   ? 3.351   22.706  -41.436 1.00 53.35  ? 2   NAG B O5  1 
HETATM 8105 O O6  . NAG F 6 .   ? 5.159   24.813  -40.812 1.00 64.75  ? 2   NAG B O6  1 
HETATM 8106 O O7  . NAG F 6 .   ? -0.009  19.454  -41.997 1.00 58.44  ? 2   NAG B O7  1 
HETATM 8107 C C1  . BMA F 6 .   ? 0.263   26.224  -41.411 1.00 71.42  ? 3   BMA B C1  1 
HETATM 8108 C C2  . BMA F 6 .   ? 0.464   27.734  -41.515 1.00 80.92  ? 3   BMA B C2  1 
HETATM 8109 C C3  . BMA F 6 .   ? -0.696  28.479  -40.816 1.00 84.99  ? 3   BMA B C3  1 
HETATM 8110 C C4  . BMA F 6 .   ? -2.084  27.978  -41.251 1.00 75.35  ? 3   BMA B C4  1 
HETATM 8111 C C5  . BMA F 6 .   ? -2.172  26.455  -41.258 1.00 74.81  ? 3   BMA B C5  1 
HETATM 8112 C C6  . BMA F 6 .   ? -3.440  25.922  -41.922 1.00 75.37  ? 3   BMA B C6  1 
HETATM 8113 O O2  . BMA F 6 .   ? 0.583   28.070  -42.871 1.00 65.22  ? 3   BMA B O2  1 
HETATM 8114 O O3  . BMA F 6 .   ? -0.499  29.850  -41.060 1.00 85.34  ? 3   BMA B O3  1 
HETATM 8115 O O4  . BMA F 6 .   ? -3.010  28.538  -40.339 1.00 89.99  ? 3   BMA B O4  1 
HETATM 8116 O O5  . BMA F 6 .   ? -1.033  25.851  -41.846 1.00 72.04  ? 3   BMA B O5  1 
HETATM 8117 O O6  . BMA F 6 .   ? -3.577  24.564  -41.564 1.00 75.72  ? 3   BMA B O6  1 
HETATM 8118 O O   . HOH G 7 .   ? 3.091   -6.133  -44.451 1.00 35.70  ? 601 HOH A O   1 
HETATM 8119 O O   . HOH G 7 .   ? 12.319  -5.000  -22.195 1.00 28.18  ? 602 HOH A O   1 
HETATM 8120 O O   . HOH G 7 .   ? 3.030   7.869   -45.486 1.00 39.52  ? 603 HOH A O   1 
HETATM 8121 O O   . HOH G 7 .   ? 11.234  -4.541  -44.788 1.00 25.74  ? 604 HOH A O   1 
HETATM 8122 O O   . HOH G 7 .   ? 3.249   20.683  -38.645 1.00 33.67  ? 605 HOH A O   1 
HETATM 8123 O O   . HOH G 7 .   ? 9.162   11.173  -42.775 1.00 34.19  ? 606 HOH A O   1 
HETATM 8124 O O   . HOH G 7 .   ? 14.572  9.615   -27.839 1.00 26.72  ? 607 HOH A O   1 
HETATM 8125 O O   . HOH G 7 .   ? 10.415  0.171   -19.610 1.00 37.06  ? 608 HOH A O   1 
HETATM 8126 O O   . HOH G 7 .   ? 19.695  9.043   -24.159 1.00 36.98  ? 609 HOH A O   1 
HETATM 8127 O O   . HOH G 7 .   ? -2.188  9.067   -39.684 1.00 38.42  ? 610 HOH A O   1 
HETATM 8128 O O   . HOH G 7 .   ? 24.096  -20.225 -26.797 1.00 31.51  ? 611 HOH A O   1 
HETATM 8129 O O   . HOH G 7 .   ? 13.297  -10.906 -23.511 1.00 17.47  ? 612 HOH A O   1 
HETATM 8130 O O   . HOH G 7 .   ? -3.300  3.845   -38.282 1.00 38.32  ? 613 HOH A O   1 
HETATM 8131 O O   . HOH G 7 .   ? 1.878   0.859   -25.280 1.00 30.31  ? 614 HOH A O   1 
HETATM 8132 O O   . HOH G 7 .   ? 15.254  9.088   -40.957 1.00 33.82  ? 615 HOH A O   1 
HETATM 8133 O O   . HOH G 7 .   ? 19.380  29.702  -30.509 1.00 53.79  ? 616 HOH A O   1 
HETATM 8134 O O   . HOH G 7 .   ? 18.952  -4.547  -31.811 1.00 22.53  ? 617 HOH A O   1 
HETATM 8135 O O   . HOH G 7 .   ? 0.168   11.860  -25.137 1.00 32.87  ? 618 HOH A O   1 
HETATM 8136 O O   . HOH G 7 .   ? 7.809   39.416  -22.598 1.00 56.15  ? 619 HOH A O   1 
HETATM 8137 O O   . HOH G 7 .   ? 0.672   -1.725  -31.738 1.00 29.45  ? 620 HOH A O   1 
HETATM 8138 O O   . HOH G 7 .   ? 16.479  -3.741  -19.793 1.00 26.52  ? 621 HOH A O   1 
HETATM 8139 O O   . HOH G 7 .   ? 3.328   -5.897  -30.320 1.00 27.53  ? 622 HOH A O   1 
HETATM 8140 O O   . HOH G 7 .   ? 16.163  9.869   -35.465 1.00 32.54  ? 623 HOH A O   1 
HETATM 8141 O O   . HOH G 7 .   ? 13.034  -1.943  -39.023 1.00 24.46  ? 624 HOH A O   1 
HETATM 8142 O O   . HOH G 7 .   ? -5.654  7.383   -33.707 1.00 32.03  ? 625 HOH A O   1 
HETATM 8143 O O   . HOH G 7 .   ? 23.065  -9.140  -29.826 1.00 45.80  ? 626 HOH A O   1 
HETATM 8144 O O   . HOH G 7 .   ? -2.205  14.177  -35.525 1.00 27.79  ? 627 HOH A O   1 
HETATM 8145 O O   . HOH G 7 .   ? 19.361  -1.977  -30.995 1.00 28.99  ? 628 HOH A O   1 
HETATM 8146 O O   . HOH G 7 .   ? -0.497  8.239   -42.566 1.00 35.31  ? 629 HOH A O   1 
HETATM 8147 O O   . HOH G 7 .   ? 9.798   -0.427  -22.961 1.00 33.46  ? 630 HOH A O   1 
HETATM 8148 O O   . HOH G 7 .   ? 9.474   -10.969 -40.381 1.00 31.39  ? 631 HOH A O   1 
HETATM 8149 O O   . HOH G 7 .   ? 7.075   -9.593  -29.411 1.00 19.70  ? 632 HOH A O   1 
HETATM 8150 O O   . HOH G 7 .   ? 14.914  -4.447  -23.186 1.00 30.34  ? 633 HOH A O   1 
HETATM 8151 O O   . HOH G 7 .   ? 25.554  -23.270 -31.485 1.00 37.97  ? 634 HOH A O   1 
HETATM 8152 O O   . HOH G 7 .   ? 22.038  -10.712 -31.395 1.00 30.66  ? 635 HOH A O   1 
HETATM 8153 O O   . HOH G 7 .   ? 4.104   18.939  -18.819 1.00 46.09  ? 636 HOH A O   1 
HETATM 8154 O O   . HOH G 7 .   ? 12.007  23.034  -25.314 1.00 51.54  ? 637 HOH A O   1 
HETATM 8155 O O   . HOH G 7 .   ? 7.134   -12.467 -47.378 1.00 39.15  ? 638 HOH A O   1 
HETATM 8156 O O   . HOH G 7 .   ? 10.464  0.194   -25.956 1.00 29.31  ? 639 HOH A O   1 
HETATM 8157 O O   . HOH G 7 .   ? 10.417  -3.310  -18.511 1.00 34.75  ? 640 HOH A O   1 
HETATM 8158 O O   . HOH G 7 .   ? 9.558   23.137  -34.732 1.00 46.55  ? 641 HOH A O   1 
HETATM 8159 O O   . HOH G 7 .   ? 14.603  10.524  -39.300 1.00 28.46  ? 642 HOH A O   1 
HETATM 8160 O O   . HOH G 7 .   ? -1.712  6.803   -39.519 1.00 33.34  ? 643 HOH A O   1 
HETATM 8161 O O   . HOH G 7 .   ? 7.138   -8.030  -31.974 1.00 33.96  ? 644 HOH A O   1 
HETATM 8162 O O   . HOH G 7 .   ? 23.871  18.449  -31.966 1.00 44.27  ? 645 HOH A O   1 
HETATM 8163 O O   . HOH G 7 .   ? 20.678  3.128   -39.525 1.00 38.39  ? 646 HOH A O   1 
HETATM 8164 O O   . HOH G 7 .   ? 15.793  12.757  -50.126 1.00 36.81  ? 647 HOH A O   1 
HETATM 8165 O O   . HOH G 7 .   ? -1.200  25.893  -30.405 1.00 36.28  ? 648 HOH A O   1 
HETATM 8166 O O   . HOH G 7 .   ? 16.480  10.349  -45.618 1.00 36.59  ? 649 HOH A O   1 
HETATM 8167 O O   . HOH G 7 .   ? 7.086   1.728   -16.392 1.00 38.78  ? 650 HOH A O   1 
HETATM 8168 O O   . HOH G 7 .   ? -0.194  5.378   -45.627 1.00 37.53  ? 651 HOH A O   1 
HETATM 8169 O O   . HOH G 7 .   ? 24.800  -27.979 -28.597 1.00 33.00  ? 652 HOH A O   1 
HETATM 8170 O O   . HOH G 7 .   ? 6.801   -9.521  -38.549 1.00 29.78  ? 653 HOH A O   1 
HETATM 8171 O O   . HOH G 7 .   ? 23.232  -12.188 -27.925 1.00 31.69  ? 654 HOH A O   1 
HETATM 8172 O O   . HOH G 7 .   ? 14.802  -5.819  -19.334 1.00 26.38  ? 655 HOH A O   1 
HETATM 8173 O O   . HOH G 7 .   ? 24.164  -27.180 -26.425 1.00 28.49  ? 656 HOH A O   1 
HETATM 8174 O O   . HOH G 7 .   ? 13.964  -12.687 -42.865 1.00 37.99  ? 657 HOH A O   1 
HETATM 8175 O O   . HOH G 7 .   ? 25.462  -26.301 -30.961 1.00 37.71  ? 658 HOH A O   1 
HETATM 8176 O O   . HOH G 7 .   ? 1.770   18.879  -39.904 1.00 32.16  ? 659 HOH A O   1 
HETATM 8177 O O   . HOH G 7 .   ? -0.753  -5.852  -31.078 1.00 42.16  ? 660 HOH A O   1 
HETATM 8178 O O   . HOH G 7 .   ? 23.261  -10.033 -25.488 1.00 29.61  ? 661 HOH A O   1 
HETATM 8179 O O   . HOH G 7 .   ? 13.253  0.958   -47.532 1.00 32.47  ? 662 HOH A O   1 
HETATM 8180 O O   . HOH G 7 .   ? 3.173   28.216  -30.675 1.00 42.65  ? 663 HOH A O   1 
HETATM 8181 O O   . HOH G 7 .   ? -4.020  -6.612  -38.999 1.00 24.98  ? 664 HOH A O   1 
HETATM 8182 O O   . HOH G 7 .   ? 2.070   19.679  -17.646 1.00 44.90  ? 665 HOH A O   1 
HETATM 8183 O O   . HOH G 7 .   ? -1.935  0.213   -35.683 1.00 33.85  ? 666 HOH A O   1 
HETATM 8184 O O   . HOH G 7 .   ? 11.614  2.466   -48.178 1.00 38.35  ? 667 HOH A O   1 
HETATM 8185 O O   . HOH G 7 .   ? 5.179   -11.894 -32.179 1.00 49.33  ? 668 HOH A O   1 
HETATM 8186 O O   . HOH G 7 .   ? 3.961   28.645  -17.920 1.00 37.19  ? 669 HOH A O   1 
HETATM 8187 O O   . HOH G 7 .   ? 9.586   -14.088 -47.640 1.00 47.05  ? 670 HOH A O   1 
HETATM 8188 O O   . HOH G 7 .   ? 16.607  -8.104  -18.349 1.00 32.20  ? 671 HOH A O   1 
HETATM 8189 O O   . HOH G 7 .   ? 3.072   -8.197  -30.375 1.00 46.59  ? 672 HOH A O   1 
HETATM 8190 O O   . HOH G 7 .   ? 1.058   -0.054  -20.085 1.00 44.53  ? 673 HOH A O   1 
HETATM 8191 O O   . HOH G 7 .   ? 17.851  11.348  -36.912 1.00 40.10  ? 674 HOH A O   1 
HETATM 8192 O O   . HOH G 7 .   ? 11.865  -5.874  -19.516 1.00 27.06  ? 675 HOH A O   1 
HETATM 8193 O O   . HOH G 7 .   ? -5.222  13.972  -35.196 1.00 34.55  ? 676 HOH A O   1 
HETATM 8194 O O   . HOH G 7 .   ? 25.395  -13.665 -29.473 1.00 32.40  ? 677 HOH A O   1 
HETATM 8195 O O   . HOH G 7 .   ? 1.992   -5.221  -26.551 1.00 32.26  ? 678 HOH A O   1 
HETATM 8196 O O   . HOH G 7 .   ? 25.565  -29.989 -29.643 1.00 39.71  ? 679 HOH A O   1 
HETATM 8197 O O   . HOH G 7 .   ? -2.411  6.741   -43.409 1.00 51.36  ? 680 HOH A O   1 
HETATM 8198 O O   . HOH G 7 .   ? 17.832  9.997   -23.162 1.00 45.29  ? 681 HOH A O   1 
HETATM 8199 O O   . HOH G 7 .   ? 3.067   15.675  -45.177 1.00 43.83  ? 682 HOH A O   1 
HETATM 8200 O O   . HOH G 7 .   ? 6.181   29.335  -16.169 1.00 41.09  ? 683 HOH A O   1 
HETATM 8201 O O   . HOH H 7 .   ? -17.272 1.068   -23.157 1.00 55.81  ? 301 HOH H O   1 
HETATM 8202 O O   . HOH H 7 .   ? -11.729 22.914  -23.227 1.00 37.06  ? 302 HOH H O   1 
HETATM 8203 O O   . HOH H 7 .   ? -46.484 47.299  0.265   1.00 63.63  ? 303 HOH H O   1 
HETATM 8204 O O   . HOH H 7 .   ? -10.103 9.624   -31.866 1.00 45.04  ? 304 HOH H O   1 
HETATM 8205 O O   . HOH H 7 .   ? -1.167  1.873   -19.840 1.00 45.26  ? 305 HOH H O   1 
HETATM 8206 O O   . HOH H 7 .   ? -5.845  22.589  -29.142 1.00 59.15  ? 306 HOH H O   1 
HETATM 8207 O O   . HOH H 7 .   ? -34.587 36.768  1.407   1.00 43.35  ? 307 HOH H O   1 
HETATM 8208 O O   . HOH H 7 .   ? -38.874 34.012  -9.902  1.00 39.52  ? 308 HOH H O   1 
HETATM 8209 O O   . HOH H 7 .   ? -19.760 10.331  -29.492 1.00 33.84  ? 309 HOH H O   1 
HETATM 8210 O O   . HOH H 7 .   ? -4.237  21.576  -26.492 1.00 31.58  ? 310 HOH H O   1 
HETATM 8211 O O   . HOH H 7 .   ? -17.223 11.248  -4.498  1.00 23.30  ? 311 HOH H O   1 
HETATM 8212 O O   . HOH H 7 .   ? -2.465  17.703  -19.898 1.00 28.43  ? 312 HOH H O   1 
HETATM 8213 O O   . HOH H 7 .   ? -24.575 15.766  -19.335 1.00 25.85  ? 313 HOH H O   1 
HETATM 8214 O O   . HOH H 7 .   ? -34.703 7.671   -4.831  1.00 19.88  ? 314 HOH H O   1 
HETATM 8215 O O   . HOH H 7 .   ? -14.880 20.675  -22.534 1.00 29.73  ? 315 HOH H O   1 
HETATM 8216 O O   . HOH H 7 .   ? -20.726 17.226  -8.582  1.00 36.36  ? 316 HOH H O   1 
HETATM 8217 O O   . HOH H 7 .   ? -34.909 21.369  0.523   1.00 25.70  ? 317 HOH H O   1 
HETATM 8218 O O   . HOH H 7 .   ? -8.749  23.968  -31.268 1.00 42.92  ? 318 HOH H O   1 
HETATM 8219 O O   . HOH H 7 .   ? -40.994 13.141  4.618   1.00 45.63  ? 319 HOH H O   1 
HETATM 8220 O O   . HOH H 7 .   ? -26.361 6.726   -22.134 1.00 38.38  ? 320 HOH H O   1 
HETATM 8221 O O   . HOH H 7 .   ? -9.016  23.013  -16.161 1.00 32.96  ? 321 HOH H O   1 
HETATM 8222 O O   . HOH H 7 .   ? -29.962 11.525  -13.421 1.00 31.43  ? 322 HOH H O   1 
HETATM 8223 O O   . HOH H 7 .   ? -29.745 12.602  -5.413  1.00 23.43  ? 323 HOH H O   1 
HETATM 8224 O O   . HOH H 7 .   ? -20.189 0.352   -9.177  1.00 26.58  ? 324 HOH H O   1 
HETATM 8225 O O   . HOH H 7 .   ? -10.751 -2.372  -20.061 1.00 37.38  ? 325 HOH H O   1 
HETATM 8226 O O   . HOH H 7 .   ? -6.493  11.211  -27.924 1.00 18.33  ? 326 HOH H O   1 
HETATM 8227 O O   . HOH H 7 .   ? -19.888 3.919   -9.166  1.00 27.19  ? 327 HOH H O   1 
HETATM 8228 O O   . HOH H 7 .   ? -44.640 34.662  7.136   1.00 42.64  ? 328 HOH H O   1 
HETATM 8229 O O   . HOH H 7 .   ? -38.827 21.671  2.622   1.00 22.22  ? 329 HOH H O   1 
HETATM 8230 O O   . HOH H 7 .   ? -10.337 -0.806  -22.393 1.00 29.48  ? 330 HOH H O   1 
HETATM 8231 O O   . HOH H 7 .   ? -26.630 3.315   -21.425 1.00 32.90  ? 331 HOH H O   1 
HETATM 8232 O O   . HOH H 7 .   ? -11.864 0.516   -26.421 1.00 30.57  ? 332 HOH H O   1 
HETATM 8233 O O   . HOH H 7 .   ? -35.730 5.210   -11.153 1.00 38.38  ? 333 HOH H O   1 
HETATM 8234 O O   . HOH H 7 .   ? -20.162 -2.120  -10.677 1.00 35.33  ? 334 HOH H O   1 
HETATM 8235 O O   . HOH H 7 .   ? -30.366 31.355  -2.561  1.00 30.01  ? 335 HOH H O   1 
HETATM 8236 O O   . HOH H 7 .   ? -22.394 -1.351  -9.754  1.00 28.09  ? 336 HOH H O   1 
HETATM 8237 O O   . HOH H 7 .   ? -10.344 10.547  -3.902  1.00 30.69  ? 337 HOH H O   1 
HETATM 8238 O O   . HOH H 7 .   ? -20.759 20.107  -12.841 1.00 37.65  ? 338 HOH H O   1 
HETATM 8239 O O   . HOH H 7 .   ? -20.931 7.954   -29.207 1.00 35.96  ? 339 HOH H O   1 
HETATM 8240 O O   . HOH H 7 .   ? -39.656 42.096  -11.925 1.00 39.16  ? 340 HOH H O   1 
HETATM 8241 O O   . HOH H 7 .   ? -23.261 8.000   -26.562 1.00 26.19  ? 341 HOH H O   1 
HETATM 8242 O O   . HOH H 7 .   ? -3.080  12.215  -16.859 1.00 30.42  ? 342 HOH H O   1 
HETATM 8243 O O   . HOH H 7 .   ? -15.626 22.415  -17.867 1.00 34.34  ? 343 HOH H O   1 
HETATM 8244 O O   . HOH H 7 .   ? -17.945 13.472  -35.770 1.00 39.34  ? 344 HOH H O   1 
HETATM 8245 O O   . HOH H 7 .   ? -8.745  6.214   -7.027  1.00 33.36  ? 345 HOH H O   1 
HETATM 8246 O O   . HOH H 7 .   ? -4.140  13.701  -13.916 1.00 30.85  ? 346 HOH H O   1 
HETATM 8247 O O   . HOH H 7 .   ? -43.383 12.383  4.205   1.00 40.72  ? 347 HOH H O   1 
HETATM 8248 O O   . HOH H 7 .   ? -29.169 -0.988  -5.365  1.00 20.99  ? 348 HOH H O   1 
HETATM 8249 O O   . HOH H 7 .   ? -40.855 16.883  2.963   1.00 34.82  ? 349 HOH H O   1 
HETATM 8250 O O   . HOH H 7 .   ? -34.075 20.391  -8.113  1.00 38.57  ? 350 HOH H O   1 
HETATM 8251 O O   . HOH H 7 .   ? -22.421 14.929  -7.217  1.00 24.28  ? 351 HOH H O   1 
HETATM 8252 O O   . HOH H 7 .   ? -30.220 -2.871  -18.850 1.00 34.73  ? 352 HOH H O   1 
HETATM 8253 O O   . HOH H 7 .   ? -32.558 9.007   -5.833  1.00 20.33  ? 353 HOH H O   1 
HETATM 8254 O O   . HOH H 7 .   ? -18.659 3.466   -34.512 1.00 41.67  ? 354 HOH H O   1 
HETATM 8255 O O   . HOH H 7 .   ? -37.109 40.778  -8.318  1.00 35.13  ? 355 HOH H O   1 
HETATM 8256 O O   . HOH H 7 .   ? -32.086 30.206  -4.778  1.00 33.87  ? 356 HOH H O   1 
HETATM 8257 O O   . HOH H 7 .   ? -30.613 14.712  0.405   1.00 28.14  ? 357 HOH H O   1 
HETATM 8258 O O   . HOH H 7 .   ? -4.640  -0.436  -14.474 1.00 31.01  ? 358 HOH H O   1 
HETATM 8259 O O   . HOH H 7 .   ? -12.574 22.599  -19.326 1.00 31.71  ? 359 HOH H O   1 
HETATM 8260 O O   . HOH H 7 .   ? -40.382 27.399  -13.105 1.00 36.29  ? 360 HOH H O   1 
HETATM 8261 O O   . HOH H 7 .   ? -24.089 -0.694  -2.712  1.00 33.92  ? 361 HOH H O   1 
HETATM 8262 O O   . HOH H 7 .   ? -37.702 19.707  -14.522 1.00 37.69  ? 362 HOH H O   1 
HETATM 8263 O O   . HOH H 7 .   ? -47.865 12.468  -8.199  1.00 34.17  ? 363 HOH H O   1 
HETATM 8264 O O   . HOH H 7 .   ? -33.100 2.510   -4.651  1.00 29.87  ? 364 HOH H O   1 
HETATM 8265 O O   . HOH H 7 .   ? -45.751 39.332  8.574   1.00 43.90  ? 365 HOH H O   1 
HETATM 8266 O O   . HOH H 7 .   ? -28.994 12.653  -8.263  1.00 25.57  ? 366 HOH H O   1 
HETATM 8267 O O   . HOH H 7 .   ? -23.226 6.231   -24.712 1.00 35.92  ? 367 HOH H O   1 
HETATM 8268 O O   . HOH H 7 .   ? -32.604 12.332  -9.457  1.00 24.55  ? 368 HOH H O   1 
HETATM 8269 O O   . HOH H 7 .   ? -20.051 18.286  -21.464 1.00 21.39  ? 369 HOH H O   1 
HETATM 8270 O O   . HOH H 7 .   ? -26.776 0.274   -3.576  1.00 24.81  ? 370 HOH H O   1 
HETATM 8271 O O   . HOH H 7 .   ? -5.168  16.916  -33.152 1.00 36.86  ? 371 HOH H O   1 
HETATM 8272 O O   . HOH H 7 .   ? -49.978 20.070  -6.615  1.00 40.26  ? 372 HOH H O   1 
HETATM 8273 O O   . HOH H 7 .   ? -21.828 17.365  -5.373  1.00 29.56  ? 373 HOH H O   1 
HETATM 8274 O O   . HOH H 7 .   ? -19.642 18.150  -3.638  1.00 37.51  ? 374 HOH H O   1 
HETATM 8275 O O   . HOH H 7 .   ? -40.334 41.533  10.213  1.00 43.25  ? 375 HOH H O   1 
HETATM 8276 O O   . HOH H 7 .   ? -13.040 22.335  -29.964 1.00 38.26  ? 376 HOH H O   1 
HETATM 8277 O O   . HOH H 7 .   ? -18.783 -5.230  -14.129 1.00 41.23  ? 377 HOH H O   1 
HETATM 8278 O O   . HOH H 7 .   ? -26.483 12.086  -8.973  1.00 24.44  ? 378 HOH H O   1 
HETATM 8279 O O   . HOH H 7 .   ? -13.634 -0.468  -27.964 1.00 38.73  ? 379 HOH H O   1 
HETATM 8280 O O   . HOH H 7 .   ? -5.898  -2.038  -21.688 1.00 37.41  ? 380 HOH H O   1 
HETATM 8281 O O   . HOH H 7 .   ? -42.728 39.290  10.418  1.00 33.11  ? 381 HOH H O   1 
HETATM 8282 O O   . HOH H 7 .   ? -5.717  9.532   -29.817 1.00 36.61  ? 382 HOH H O   1 
HETATM 8283 O O   . HOH H 7 .   ? -11.424 23.269  -17.414 1.00 39.28  ? 383 HOH H O   1 
HETATM 8284 O O   . HOH H 7 .   ? -37.360 19.873  2.384   1.00 35.75  ? 384 HOH H O   1 
HETATM 8285 O O   . HOH H 7 .   ? -6.599  23.463  -22.267 1.00 33.02  ? 385 HOH H O   1 
HETATM 8286 O O   . HOH H 7 .   ? -13.355 11.630  -1.526  1.00 31.00  ? 386 HOH H O   1 
HETATM 8287 O O   . HOH H 7 .   ? -36.681 5.763   -13.454 1.00 26.19  ? 387 HOH H O   1 
HETATM 8288 O O   . HOH H 7 .   ? -29.648 14.711  -9.230  1.00 36.16  ? 388 HOH H O   1 
HETATM 8289 O O   . HOH H 7 .   ? -7.554  9.324   -32.089 1.00 29.42  ? 389 HOH H O   1 
HETATM 8290 O O   . HOH H 7 .   ? -24.453 12.604  -26.187 1.00 37.52  ? 390 HOH H O   1 
HETATM 8291 O O   . HOH H 7 .   ? -28.635 10.785  -3.549  1.00 29.16  ? 391 HOH H O   1 
HETATM 8292 O O   . HOH H 7 .   ? -27.160 19.443  -0.729  1.00 38.74  ? 392 HOH H O   1 
HETATM 8293 O O   . HOH H 7 .   ? -55.233 37.598  7.651   1.00 47.77  ? 393 HOH H O   1 
HETATM 8294 O O   . HOH I 7 .   ? 10.095  -30.906 -35.596 1.00 36.52  ? 301 HOH F O   1 
HETATM 8295 O O   . HOH I 7 .   ? -9.124  -36.750 -9.189  1.00 35.54  ? 302 HOH F O   1 
HETATM 8296 O O   . HOH I 7 .   ? -5.704  -68.049 -18.711 1.00 55.24  ? 303 HOH F O   1 
HETATM 8297 O O   . HOH I 7 .   ? 14.744  -25.142 -10.654 1.00 39.76  ? 304 HOH F O   1 
HETATM 8298 O O   . HOH I 7 .   ? 10.553  -28.046 -10.044 1.00 31.92  ? 305 HOH F O   1 
HETATM 8299 O O   . HOH I 7 .   ? 7.293   -22.006 -13.810 1.00 26.23  ? 306 HOH F O   1 
HETATM 8300 O O   . HOH I 7 .   ? -19.261 -53.000 -16.675 1.00 53.93  ? 307 HOH F O   1 
HETATM 8301 O O   . HOH I 7 .   ? 8.157   -31.359 -12.525 1.00 18.10  ? 308 HOH F O   1 
HETATM 8302 O O   . HOH I 7 .   ? -5.670  -37.176 -28.874 1.00 50.74  ? 309 HOH F O   1 
HETATM 8303 O O   . HOH I 7 .   ? 5.420   -14.444 -33.720 1.00 34.32  ? 310 HOH F O   1 
HETATM 8304 O O   . HOH I 7 .   ? 1.996   -38.575 -19.824 1.00 31.19  ? 311 HOH F O   1 
HETATM 8305 O O   . HOH I 7 .   ? -6.349  -28.828 -27.899 1.00 23.98  ? 312 HOH F O   1 
HETATM 8306 O O   . HOH I 7 .   ? -6.474  -14.130 -19.537 1.00 36.96  ? 313 HOH F O   1 
HETATM 8307 O O   . HOH I 7 .   ? 14.962  -20.183 -30.239 1.00 25.37  ? 314 HOH F O   1 
HETATM 8308 O O   . HOH I 7 .   ? 11.691  -9.186  -19.965 1.00 33.56  ? 315 HOH F O   1 
HETATM 8309 O O   . HOH I 7 .   ? 5.466   -14.883 -16.145 1.00 25.02  ? 316 HOH F O   1 
HETATM 8310 O O   . HOH I 7 .   ? -5.900  -35.120 -31.538 1.00 33.19  ? 317 HOH F O   1 
HETATM 8311 O O   . HOH I 7 .   ? -4.286  -46.673 -22.453 1.00 49.57  ? 318 HOH F O   1 
HETATM 8312 O O   . HOH I 7 .   ? 14.304  -20.680 -22.913 1.00 26.28  ? 319 HOH F O   1 
HETATM 8313 O O   . HOH I 7 .   ? -4.173  -23.871 -7.604  1.00 40.56  ? 320 HOH F O   1 
HETATM 8314 O O   . HOH I 7 .   ? -4.301  -35.323 -26.247 1.00 47.39  ? 321 HOH F O   1 
HETATM 8315 O O   . HOH I 7 .   ? 9.337   -38.343 -18.335 1.00 29.05  ? 322 HOH F O   1 
HETATM 8316 O O   . HOH I 7 .   ? 14.300  -29.903 -12.600 1.00 39.70  ? 323 HOH F O   1 
HETATM 8317 O O   . HOH I 7 .   ? 4.111   -32.716 -11.426 1.00 33.56  ? 324 HOH F O   1 
HETATM 8318 O O   . HOH I 7 .   ? 22.302  -17.921 -22.681 1.00 25.73  ? 325 HOH F O   1 
HETATM 8319 O O   . HOH I 7 .   ? 6.492   -10.480 -20.428 1.00 29.42  ? 326 HOH F O   1 
HETATM 8320 O O   . HOH I 7 .   ? 21.129  -34.319 -27.113 1.00 52.90  ? 327 HOH F O   1 
HETATM 8321 O O   . HOH I 7 .   ? 20.800  -36.845 -27.836 1.00 44.03  ? 328 HOH F O   1 
HETATM 8322 O O   . HOH I 7 .   ? 0.275   -16.098 -16.567 1.00 33.67  ? 329 HOH F O   1 
HETATM 8323 O O   . HOH I 7 .   ? 17.503  -10.501 -20.419 1.00 23.76  ? 330 HOH F O   1 
HETATM 8324 O O   . HOH I 7 .   ? 8.477   -33.783 -13.415 1.00 27.03  ? 331 HOH F O   1 
HETATM 8325 O O   . HOH I 7 .   ? 13.875  -10.909 -18.869 1.00 34.31  ? 332 HOH F O   1 
HETATM 8326 O O   . HOH I 7 .   ? 20.707  -25.709 -21.919 1.00 32.78  ? 333 HOH F O   1 
HETATM 8327 O O   . HOH I 7 .   ? -6.346  -18.412 -24.968 1.00 43.06  ? 334 HOH F O   1 
HETATM 8328 O O   . HOH I 7 .   ? -6.929  -40.707 -7.006  1.00 36.50  ? 335 HOH F O   1 
HETATM 8329 O O   . HOH I 7 .   ? 12.092  -31.331 -12.374 1.00 28.47  ? 336 HOH F O   1 
HETATM 8330 O O   . HOH I 7 .   ? 1.478   -20.164 -11.838 1.00 33.45  ? 337 HOH F O   1 
HETATM 8331 O O   . HOH I 7 .   ? 13.041  -36.057 -27.137 1.00 36.84  ? 338 HOH F O   1 
HETATM 8332 O O   . HOH I 7 .   ? 10.643  -21.913 -11.500 1.00 34.69  ? 339 HOH F O   1 
HETATM 8333 O O   . HOH I 7 .   ? 12.644  -18.937 -40.383 1.00 31.04  ? 340 HOH F O   1 
HETATM 8334 O O   . HOH I 7 .   ? 23.401  -31.542 -30.950 1.00 55.78  ? 341 HOH F O   1 
HETATM 8335 O O   . HOH I 7 .   ? 6.199   -37.864 -15.577 1.00 36.81  ? 342 HOH F O   1 
HETATM 8336 O O   . HOH I 7 .   ? -1.435  -39.999 -12.137 1.00 35.70  ? 343 HOH F O   1 
HETATM 8337 O O   . HOH I 7 .   ? -3.822  -20.181 -28.017 1.00 37.61  ? 344 HOH F O   1 
HETATM 8338 O O   . HOH I 7 .   ? -1.420  -40.000 -16.117 1.00 40.40  ? 345 HOH F O   1 
HETATM 8339 O O   . HOH I 7 .   ? -6.661  -27.762 -25.810 1.00 35.93  ? 346 HOH F O   1 
HETATM 8340 O O   . HOH I 7 .   ? 15.370  -22.806 -38.934 1.00 34.91  ? 347 HOH F O   1 
HETATM 8341 O O   . HOH I 7 .   ? 20.843  -22.647 -20.069 1.00 36.24  ? 348 HOH F O   1 
HETATM 8342 O O   . HOH I 7 .   ? 25.854  -21.371 -24.861 1.00 40.29  ? 349 HOH F O   1 
HETATM 8343 O O   . HOH I 7 .   ? -2.741  -37.861 -16.443 1.00 29.41  ? 350 HOH F O   1 
HETATM 8344 O O   . HOH I 7 .   ? 15.040  -24.453 -37.268 1.00 33.01  ? 351 HOH F O   1 
HETATM 8345 O O   . HOH I 7 .   ? -13.310 -27.321 -13.738 1.00 24.96  ? 352 HOH F O   1 
HETATM 8346 O O   . HOH I 7 .   ? -7.460  -39.721 -18.379 1.00 36.09  ? 353 HOH F O   1 
HETATM 8347 O O   . HOH I 7 .   ? -2.689  -29.497 -5.486  1.00 37.48  ? 354 HOH F O   1 
HETATM 8348 O O   . HOH I 7 .   ? 2.753   -38.813 -24.042 1.00 33.69  ? 355 HOH F O   1 
HETATM 8349 O O   . HOH I 7 .   ? 12.860  -18.212 -15.583 1.00 20.88  ? 356 HOH F O   1 
HETATM 8350 O O   . HOH I 7 .   ? 0.925   -12.559 -21.809 1.00 15.59  ? 357 HOH F O   1 
HETATM 8351 O O   . HOH I 7 .   ? -12.707 -77.396 -19.353 1.00 61.64  ? 358 HOH F O   1 
HETATM 8352 O O   . HOH I 7 .   ? 10.012  -32.933 -33.361 1.00 37.15  ? 359 HOH F O   1 
HETATM 8353 O O   . HOH I 7 .   ? -4.683  -16.577 -26.739 1.00 36.33  ? 360 HOH F O   1 
HETATM 8354 O O   . HOH I 7 .   ? 8.011   -11.156 -18.528 1.00 36.39  ? 361 HOH F O   1 
HETATM 8355 O O   . HOH I 7 .   ? 3.109   -15.352 -28.933 1.00 27.96  ? 362 HOH F O   1 
HETATM 8356 O O   . HOH I 7 .   ? 23.515  -33.996 -27.624 1.00 46.55  ? 363 HOH F O   1 
HETATM 8357 O O   . HOH I 7 .   ? 2.561   -27.921 -7.759  1.00 28.15  ? 364 HOH F O   1 
HETATM 8358 O O   . HOH I 7 .   ? 0.409   -15.575 -13.890 1.00 29.78  ? 365 HOH F O   1 
HETATM 8359 O O   . HOH I 7 .   ? 3.407   -13.402 -27.854 1.00 33.91  ? 366 HOH F O   1 
HETATM 8360 O O   . HOH I 7 .   ? 3.247   -14.357 -31.766 1.00 44.18  ? 367 HOH F O   1 
HETATM 8361 O O   . HOH I 7 .   ? 13.418  -33.138 -31.137 1.00 40.37  ? 368 HOH F O   1 
HETATM 8362 O O   . HOH I 7 .   ? 15.372  -19.588 -40.825 1.00 33.95  ? 369 HOH F O   1 
HETATM 8363 O O   . HOH I 7 .   ? -7.047  -39.448 -21.582 1.00 40.16  ? 370 HOH F O   1 
HETATM 8364 O O   . HOH I 7 .   ? 1.336   -39.631 -11.213 1.00 43.46  ? 371 HOH F O   1 
HETATM 8365 O O   . HOH I 7 .   ? 16.776  -21.275 -39.980 1.00 29.39  ? 372 HOH F O   1 
HETATM 8366 O O   . HOH J 7 .   ? 5.315   16.106  4.702   1.00 50.71  ? 301 HOH L O   1 
HETATM 8367 O O   . HOH J 7 .   ? -1.684  1.742   -13.196 1.00 41.99  ? 302 HOH L O   1 
HETATM 8368 O O   . HOH J 7 .   ? 2.430   29.290  -8.148  1.00 37.44  ? 303 HOH L O   1 
HETATM 8369 O O   . HOH J 7 .   ? 8.026   21.557  -5.539  1.00 42.24  ? 304 HOH L O   1 
HETATM 8370 O O   . HOH J 7 .   ? -29.778 22.350  13.228  1.00 32.52  ? 305 HOH L O   1 
HETATM 8371 O O   . HOH J 7 .   ? -13.317 27.267  -11.068 1.00 41.19  ? 306 HOH L O   1 
HETATM 8372 O O   . HOH J 7 .   ? -10.817 30.893  -11.452 1.00 44.11  ? 307 HOH L O   1 
HETATM 8373 O O   . HOH J 7 .   ? -4.975  28.213  6.321   1.00 42.99  ? 308 HOH L O   1 
HETATM 8374 O O   . HOH J 7 .   ? -58.480 25.865  17.187  1.00 51.27  ? 309 HOH L O   1 
HETATM 8375 O O   . HOH J 7 .   ? -13.489 18.613  2.860   1.00 38.59  ? 310 HOH L O   1 
HETATM 8376 O O   . HOH J 7 .   ? -33.595 21.000  12.606  1.00 30.01  ? 311 HOH L O   1 
HETATM 8377 O O   . HOH J 7 .   ? -39.047 16.693  7.194   1.00 32.81  ? 312 HOH L O   1 
HETATM 8378 O O   . HOH J 7 .   ? -1.589  3.797   0.907   1.00 32.74  ? 313 HOH L O   1 
HETATM 8379 O O   . HOH J 7 .   ? -4.381  24.697  -20.775 1.00 47.08  ? 314 HOH L O   1 
HETATM 8380 O O   . HOH J 7 .   ? 1.880   33.376  1.266   1.00 46.98  ? 315 HOH L O   1 
HETATM 8381 O O   . HOH J 7 .   ? 1.360   28.662  -2.240  1.00 36.99  ? 316 HOH L O   1 
HETATM 8382 O O   . HOH J 7 .   ? 7.772   14.799  -3.978  1.00 40.95  ? 317 HOH L O   1 
HETATM 8383 O O   . HOH J 7 .   ? 9.923   14.071  -11.208 1.00 36.59  ? 318 HOH L O   1 
HETATM 8384 O O   . HOH J 7 .   ? -19.674 29.154  8.122   1.00 38.09  ? 319 HOH L O   1 
HETATM 8385 O O   . HOH J 7 .   ? 1.596   5.897   0.911   1.00 37.49  ? 320 HOH L O   1 
HETATM 8386 O O   . HOH J 7 .   ? -31.021 18.257  18.368  1.00 48.15  ? 321 HOH L O   1 
HETATM 8387 O O   . HOH J 7 .   ? -25.591 24.816  10.302  1.00 38.97  ? 322 HOH L O   1 
HETATM 8388 O O   . HOH J 7 .   ? -32.997 24.428  20.881  1.00 45.49  ? 323 HOH L O   1 
HETATM 8389 O O   . HOH J 7 .   ? -1.583  6.529   -5.419  1.00 41.89  ? 324 HOH L O   1 
HETATM 8390 O O   . HOH J 7 .   ? -11.658 32.442  -8.887  1.00 43.91  ? 325 HOH L O   1 
HETATM 8391 O O   . HOH J 7 .   ? -7.665  40.403  -5.792  1.00 43.41  ? 326 HOH L O   1 
HETATM 8392 O O   . HOH J 7 .   ? -7.573  25.587  -16.196 1.00 28.28  ? 327 HOH L O   1 
HETATM 8393 O O   . HOH J 7 .   ? -24.092 25.901  1.677   1.00 41.82  ? 328 HOH L O   1 
HETATM 8394 O O   . HOH J 7 .   ? -36.620 16.547  14.578  1.00 21.99  ? 329 HOH L O   1 
HETATM 8395 O O   . HOH J 7 .   ? 1.699   23.385  -4.477  1.00 27.23  ? 330 HOH L O   1 
HETATM 8396 O O   . HOH J 7 .   ? -27.511 22.064  11.057  1.00 41.29  ? 331 HOH L O   1 
HETATM 8397 O O   . HOH J 7 .   ? -48.695 27.232  5.259   1.00 33.16  ? 332 HOH L O   1 
HETATM 8398 O O   . HOH J 7 .   ? -17.289 36.122  11.383  1.00 35.03  ? 333 HOH L O   1 
HETATM 8399 O O   . HOH J 7 .   ? -15.330 25.246  -10.703 1.00 23.88  ? 334 HOH L O   1 
HETATM 8400 O O   . HOH J 7 .   ? -32.071 26.307  24.035  1.00 40.91  ? 335 HOH L O   1 
HETATM 8401 O O   . HOH J 7 .   ? -27.868 31.915  20.521  1.00 33.40  ? 336 HOH L O   1 
HETATM 8402 O O   . HOH J 7 .   ? -15.981 27.435  6.904   1.00 42.05  ? 337 HOH L O   1 
HETATM 8403 O O   . HOH J 7 .   ? -33.357 18.500  11.188  1.00 35.89  ? 338 HOH L O   1 
HETATM 8404 O O   . HOH J 7 .   ? -17.172 30.936  -6.970  1.00 36.17  ? 339 HOH L O   1 
HETATM 8405 O O   . HOH J 7 .   ? -11.885 13.753  -3.062  1.00 21.85  ? 340 HOH L O   1 
HETATM 8406 O O   . HOH J 7 .   ? -6.813  17.449  7.791   1.00 35.75  ? 341 HOH L O   1 
HETATM 8407 O O   . HOH J 7 .   ? -28.981 36.423  0.743   1.00 32.98  ? 342 HOH L O   1 
HETATM 8408 O O   . HOH J 7 .   ? -30.904 19.984  14.972  1.00 35.80  ? 343 HOH L O   1 
HETATM 8409 O O   . HOH J 7 .   ? -23.414 30.171  15.029  1.00 36.11  ? 344 HOH L O   1 
HETATM 8410 O O   . HOH J 7 .   ? -43.729 23.140  21.658  1.00 34.56  ? 345 HOH L O   1 
HETATM 8411 O O   . HOH J 7 .   ? -21.029 28.568  -1.355  1.00 37.46  ? 346 HOH L O   1 
HETATM 8412 O O   . HOH J 7 .   ? -13.095 23.393  -15.924 1.00 29.82  ? 347 HOH L O   1 
HETATM 8413 O O   . HOH J 7 .   ? 2.732   18.636  -15.259 1.00 32.79  ? 348 HOH L O   1 
HETATM 8414 O O   . HOH J 7 .   ? -1.286  11.962  3.355   1.00 29.87  ? 349 HOH L O   1 
HETATM 8415 O O   . HOH J 7 .   ? -5.709  10.463  -1.157  1.00 30.35  ? 350 HOH L O   1 
HETATM 8416 O O   . HOH J 7 .   ? -30.873 38.207  8.829   1.00 37.26  ? 351 HOH L O   1 
HETATM 8417 O O   . HOH J 7 .   ? 7.759   21.011  -9.079  1.00 42.68  ? 352 HOH L O   1 
HETATM 8418 O O   . HOH J 7 .   ? -16.899 19.875  -4.252  1.00 29.06  ? 353 HOH L O   1 
HETATM 8419 O O   . HOH J 7 .   ? -27.693 32.256  0.451   1.00 33.20  ? 354 HOH L O   1 
HETATM 8420 O O   . HOH J 7 .   ? -15.109 40.048  3.828   1.00 41.98  ? 355 HOH L O   1 
HETATM 8421 O O   . HOH J 7 .   ? -21.534 30.215  -3.289  1.00 27.04  ? 356 HOH L O   1 
HETATM 8422 O O   . HOH J 7 .   ? -42.065 31.257  21.070  1.00 45.13  ? 357 HOH L O   1 
HETATM 8423 O O   . HOH J 7 .   ? -11.159 29.696  8.866   1.00 40.96  ? 358 HOH L O   1 
HETATM 8424 O O   . HOH J 7 .   ? -5.619  31.125  5.516   1.00 40.37  ? 359 HOH L O   1 
HETATM 8425 O O   . HOH J 7 .   ? -25.597 31.668  21.101  1.00 43.65  ? 360 HOH L O   1 
HETATM 8426 O O   . HOH J 7 .   ? -43.670 14.317  20.433  1.00 35.24  ? 361 HOH L O   1 
HETATM 8427 O O   . HOH J 7 .   ? 2.755   29.885  -15.922 1.00 37.80  ? 362 HOH L O   1 
HETATM 8428 O O   . HOH J 7 .   ? -36.355 22.747  1.937   1.00 17.77  ? 363 HOH L O   1 
HETATM 8429 O O   . HOH J 7 .   ? -4.062  24.377  8.552   1.00 44.57  ? 364 HOH L O   1 
HETATM 8430 O O   . HOH J 7 .   ? -28.699 34.119  2.053   1.00 30.74  ? 365 HOH L O   1 
HETATM 8431 O O   . HOH J 7 .   ? -35.894 21.471  4.766   1.00 25.87  ? 366 HOH L O   1 
HETATM 8432 O O   . HOH J 7 .   ? -39.421 12.300  17.732  1.00 23.73  ? 367 HOH L O   1 
HETATM 8433 O O   . HOH J 7 .   ? -36.044 12.387  8.476   1.00 21.41  ? 368 HOH L O   1 
HETATM 8434 O O   . HOH J 7 .   ? -31.010 17.249  8.276   1.00 29.90  ? 369 HOH L O   1 
HETATM 8435 O O   . HOH J 7 .   ? -17.717 32.467  -10.132 1.00 39.09  ? 370 HOH L O   1 
HETATM 8436 O O   . HOH J 7 .   ? -18.122 39.399  13.547  1.00 30.74  ? 371 HOH L O   1 
HETATM 8437 O O   . HOH J 7 .   ? -15.831 26.788  4.646   1.00 35.28  ? 372 HOH L O   1 
HETATM 8438 O O   . HOH J 7 .   ? -57.071 12.430  12.441  1.00 38.10  ? 373 HOH L O   1 
HETATM 8439 O O   . HOH J 7 .   ? -35.028 18.645  16.547  1.00 41.68  ? 374 HOH L O   1 
HETATM 8440 O O   . HOH J 7 .   ? 0.463   37.459  -5.328  1.00 37.17  ? 375 HOH L O   1 
HETATM 8441 O O   . HOH J 7 .   ? -38.423 16.735  4.175   1.00 30.45  ? 376 HOH L O   1 
HETATM 8442 O O   . HOH J 7 .   ? -43.674 33.021  17.873  1.00 41.43  ? 377 HOH L O   1 
HETATM 8443 O O   . HOH J 7 .   ? -36.184 36.505  14.100  1.00 23.98  ? 378 HOH L O   1 
HETATM 8444 O O   . HOH J 7 .   ? -11.740 22.402  9.269   1.00 36.40  ? 379 HOH L O   1 
HETATM 8445 O O   . HOH J 7 .   ? -28.164 27.368  -3.356  1.00 33.69  ? 380 HOH L O   1 
HETATM 8446 O O   . HOH J 7 .   ? -26.831 21.923  0.553   1.00 34.38  ? 381 HOH L O   1 
HETATM 8447 O O   . HOH J 7 .   ? -8.676  9.632   -6.248  1.00 10.99  ? 382 HOH L O   1 
HETATM 8448 O O   . HOH J 7 .   ? -17.472 32.959  13.386  1.00 32.32  ? 383 HOH L O   1 
HETATM 8449 O O   . HOH J 7 .   ? -38.716 33.216  22.052  1.00 39.91  ? 384 HOH L O   1 
HETATM 8450 O O   . HOH J 7 .   ? 8.498   8.498   0.000   0.50 21.40  ? 385 HOH L O   1 
HETATM 8451 O O   . HOH J 7 .   ? -24.512 29.924  19.736  1.00 41.99  ? 386 HOH L O   1 
HETATM 8452 O O   . HOH J 7 .   ? -28.627 20.923  1.847   1.00 26.74  ? 387 HOH L O   1 
HETATM 8453 O O   . HOH J 7 .   ? -15.786 17.919  -0.444  1.00 33.07  ? 388 HOH L O   1 
HETATM 8454 O O   . HOH J 7 .   ? -33.038 24.353  25.621  1.00 37.54  ? 389 HOH L O   1 
HETATM 8455 O O   . HOH J 7 .   ? 3.536   30.721  -13.118 1.00 34.88  ? 390 HOH L O   1 
HETATM 8456 O O   . HOH J 7 .   ? -20.265 20.894  -6.735  1.00 36.72  ? 391 HOH L O   1 
HETATM 8457 O O   . HOH J 7 .   ? -26.452 23.706  -2.941  1.00 38.59  ? 392 HOH L O   1 
HETATM 8458 O O   . HOH J 7 .   ? 4.608   35.404  -10.442 1.00 36.42  ? 393 HOH L O   1 
HETATM 8459 O O   . HOH J 7 .   ? -32.697 15.018  14.832  1.00 30.82  ? 394 HOH L O   1 
HETATM 8460 O O   . HOH J 7 .   ? -22.998 23.795  10.045  1.00 35.75  ? 395 HOH L O   1 
HETATM 8461 O O   . HOH J 7 .   ? -1.445  19.354  5.619   1.00 39.61  ? 396 HOH L O   1 
HETATM 8462 O O   . HOH J 7 .   ? -6.415  7.854   -1.839  1.00 31.93  ? 397 HOH L O   1 
HETATM 8463 O O   . HOH J 7 .   ? -2.490  0.307   -14.760 1.00 37.16  ? 398 HOH L O   1 
HETATM 8464 O O   . HOH J 7 .   ? -19.773 22.127  -3.971  1.00 31.35  ? 399 HOH L O   1 
HETATM 8465 O O   . HOH J 7 .   ? -18.749 39.461  16.291  1.00 35.37  ? 400 HOH L O   1 
HETATM 8466 O O   . HOH J 7 .   ? -19.749 31.434  -11.921 1.00 49.21  ? 401 HOH L O   1 
HETATM 8467 O O   . HOH K 7 .   ? 5.457   -37.853 -50.873 1.00 61.94  ? 301 HOH G O   1 
HETATM 8468 O O   . HOH K 7 .   ? -18.740 -61.387 -13.162 1.00 68.99  ? 302 HOH G O   1 
HETATM 8469 O O   . HOH K 7 .   ? -1.487  -14.193 -36.980 1.00 46.44  ? 303 HOH G O   1 
HETATM 8470 O O   . HOH K 7 .   ? -7.789  -45.680 -35.580 1.00 68.56  ? 304 HOH G O   1 
HETATM 8471 O O   . HOH K 7 .   ? -22.556 -71.357 -30.960 1.00 50.89  ? 305 HOH G O   1 
HETATM 8472 O O   . HOH K 7 .   ? 3.049   -27.059 -52.615 1.00 43.84  ? 306 HOH G O   1 
HETATM 8473 O O   . HOH K 7 .   ? -12.366 -22.819 -39.675 1.00 41.68  ? 307 HOH G O   1 
HETATM 8474 O O   . HOH K 7 .   ? 10.261  -40.456 -48.605 1.00 50.08  ? 308 HOH G O   1 
HETATM 8475 O O   . HOH K 7 .   ? 9.656   -27.087 -52.277 1.00 59.56  ? 309 HOH G O   1 
HETATM 8476 O O   . HOH K 7 .   ? -13.741 -47.637 -44.573 1.00 37.51  ? 310 HOH G O   1 
HETATM 8477 O O   . HOH K 7 .   ? -25.258 -55.300 -32.065 1.00 31.37  ? 311 HOH G O   1 
HETATM 8478 O O   . HOH K 7 .   ? -6.177  -29.536 -50.827 1.00 38.90  ? 312 HOH G O   1 
HETATM 8479 O O   . HOH K 7 .   ? 8.434   -41.093 -52.408 1.00 66.01  ? 313 HOH G O   1 
HETATM 8480 O O   . HOH K 7 .   ? -2.441  -33.840 -55.072 1.00 56.72  ? 314 HOH G O   1 
HETATM 8481 O O   . HOH K 7 .   ? 3.552   -38.277 -56.845 1.00 59.89  ? 315 HOH G O   1 
HETATM 8482 O O   . HOH K 7 .   ? -25.440 -60.147 -12.303 1.00 52.48  ? 316 HOH G O   1 
HETATM 8483 O O   . HOH K 7 .   ? -25.199 -47.470 -24.663 1.00 37.74  ? 317 HOH G O   1 
HETATM 8484 O O   . HOH K 7 .   ? -25.153 -54.122 -28.139 1.00 28.46  ? 318 HOH G O   1 
HETATM 8485 O O   . HOH K 7 .   ? -20.547 -53.119 -32.022 1.00 42.16  ? 319 HOH G O   1 
HETATM 8486 O O   . HOH K 7 .   ? -32.151 -62.881 -26.681 1.00 35.41  ? 320 HOH G O   1 
HETATM 8487 O O   . HOH K 7 .   ? -19.496 -52.629 -23.424 1.00 35.40  ? 321 HOH G O   1 
HETATM 8488 O O   . HOH K 7 .   ? -27.730 -55.707 -17.180 1.00 48.10  ? 322 HOH G O   1 
HETATM 8489 O O   . HOH K 7 .   ? -31.275 -63.348 -36.965 1.00 36.91  ? 323 HOH G O   1 
HETATM 8490 O O   . HOH K 7 .   ? 11.559  -31.492 -38.740 1.00 45.72  ? 324 HOH G O   1 
HETATM 8491 O O   . HOH K 7 .   ? -12.314 -54.304 -25.097 1.00 24.60  ? 325 HOH G O   1 
HETATM 8492 O O   . HOH K 7 .   ? 9.024   -26.872 -49.980 1.00 45.98  ? 326 HOH G O   1 
HETATM 8493 O O   . HOH K 7 .   ? -14.331 -52.671 -27.608 1.00 28.58  ? 327 HOH G O   1 
HETATM 8494 O O   . HOH K 7 .   ? 4.557   -36.676 -58.274 1.00 63.30  ? 328 HOH G O   1 
HETATM 8495 O O   . HOH K 7 .   ? -13.892 -63.877 -41.336 1.00 44.82  ? 329 HOH G O   1 
HETATM 8496 O O   . HOH K 7 .   ? -10.021 -38.693 -50.102 1.00 36.65  ? 330 HOH G O   1 
HETATM 8497 O O   . HOH K 7 .   ? 4.654   -37.716 -35.513 1.00 39.78  ? 331 HOH G O   1 
HETATM 8498 O O   . HOH K 7 .   ? -3.152  -21.472 -29.839 1.00 25.18  ? 332 HOH G O   1 
HETATM 8499 O O   . HOH K 7 .   ? -15.461 -56.719 -14.880 1.00 43.94  ? 333 HOH G O   1 
HETATM 8500 O O   . HOH K 7 .   ? -27.423 -65.719 -31.261 1.00 36.70  ? 334 HOH G O   1 
HETATM 8501 O O   . HOH K 7 .   ? -29.560 -58.442 -21.997 1.00 38.45  ? 335 HOH G O   1 
HETATM 8502 O O   . HOH K 7 .   ? -18.901 -47.574 -29.568 1.00 35.47  ? 336 HOH G O   1 
HETATM 8503 O O   . HOH K 7 .   ? 7.216   -37.939 -30.233 1.00 38.14  ? 337 HOH G O   1 
HETATM 8504 O O   . HOH K 7 .   ? 1.860   -17.025 -29.841 1.00 29.25  ? 338 HOH G O   1 
HETATM 8505 O O   . HOH K 7 .   ? 11.791  -40.237 -52.849 1.00 49.64  ? 339 HOH G O   1 
HETATM 8506 O O   . HOH K 7 .   ? -7.747  -21.281 -35.742 1.00 35.54  ? 340 HOH G O   1 
HETATM 8507 O O   . HOH K 7 .   ? 2.385   -43.368 -39.669 1.00 46.67  ? 341 HOH G O   1 
HETATM 8508 O O   . HOH K 7 .   ? 16.568  -20.519 -42.824 1.00 35.49  ? 342 HOH G O   1 
HETATM 8509 O O   . HOH K 7 .   ? -12.788 -61.948 -20.218 1.00 30.75  ? 343 HOH G O   1 
HETATM 8510 O O   . HOH K 7 .   ? -21.378 -50.997 -23.266 1.00 32.18  ? 344 HOH G O   1 
HETATM 8511 O O   . HOH K 7 .   ? -21.015 -75.024 -23.351 1.00 50.89  ? 345 HOH G O   1 
HETATM 8512 O O   . HOH K 7 .   ? -13.086 -65.856 -39.763 1.00 47.38  ? 346 HOH G O   1 
HETATM 8513 O O   . HOH K 7 .   ? -13.400 -52.414 -24.244 1.00 30.54  ? 347 HOH G O   1 
HETATM 8514 O O   . HOH K 7 .   ? 4.891   -8.261  -42.460 1.00 38.76  ? 348 HOH G O   1 
HETATM 8515 O O   . HOH K 7 .   ? 9.194   -38.950 -44.369 1.00 44.56  ? 349 HOH G O   1 
HETATM 8516 O O   . HOH K 7 .   ? -34.775 -66.522 -20.258 1.00 31.16  ? 350 HOH G O   1 
HETATM 8517 O O   . HOH K 7 .   ? -8.224  -19.939 -33.580 1.00 41.20  ? 351 HOH G O   1 
HETATM 8518 O O   . HOH K 7 .   ? 3.519   -12.987 -33.561 1.00 36.80  ? 352 HOH G O   1 
HETATM 8519 O O   . HOH K 7 .   ? 12.240  -34.005 -39.106 1.00 40.36  ? 353 HOH G O   1 
HETATM 8520 O O   . HOH K 7 .   ? -0.444  -44.883 -30.627 1.00 47.44  ? 354 HOH G O   1 
HETATM 8521 O O   . HOH K 7 .   ? 14.405  -25.908 -39.144 1.00 34.90  ? 355 HOH G O   1 
# 
