data_9CP5
# 
_entry.id   9CP5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CP5         pdb_00009cp5 10.2210/pdb9cp5/pdb 
WWPDB D_1000286000 ?            ?                   
EMDB  EMD-45800    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-07 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CP5 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB  .                                                                      9CP4      unspecified            
EMDB 'Cryo-EM structure of human GAT3, apo state, inward-open conformation' EMD-45800 'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gati@usc.edu 
_pdbx_contact_author.name_first         Cornelius 
_pdbx_contact_author.name_last          Gati 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3693-7009 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yadav, R.' 1 0000-0003-2879-0465 
'Han, G.W.' 2 0000-0003-4107-835X 
'Gati, C.'  3 0000-0003-3693-7009 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                3830 
_citation.page_last                 3830 
_citation.title                     'Molecular basis of human GABA transporter 3 inhibition.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-59066-w 
_citation.pdbx_database_id_PubMed   40268946 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yadav, R.' 1 ?                   
primary 'Han, G.W.' 2 ?                   
primary 'Gati, C.'  3 0000-0003-3693-7009 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Sodium- and chloride-dependent GABA transporter 3' 71518.500 1 ? 
'N327H, Y497S, D498E, N499D, E501R, Y506F, R507P' ? ? 
2 polymer     man '9D5 heavy chain'                                   26242.297 1 ? ? ? ? 
3 polymer     man '9D5 light chain'                                   23306.586 1 ? ? ? ? 
4 non-polymer syn 'CHLORIDE ION'                                      35.453    1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'GAT-3,Solute carrier family 6 member 11' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLC
YKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSN
CFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY
FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTAL
GSYNNYHNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFF
MMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA
IFECICIGWVYGSNRFSEDIRDMIGFPPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALS
SMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAKLKSDGTIAAITEKETHFAAALEVLF
Q
;
;MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLC
YKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSN
CFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY
FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTAL
GSYNNYHNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFF
MMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA
IFECICIGWVYGSNRFSEDIRDMIGFPPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALS
SMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAKLKSDGTIAAITEKETHFAAALEVLF
Q
;
A ? 
2 'polypeptide(L)' no no 
;EVQLVESGGGLVKPGGSLKLSCAASGFTFSSYAMSWVRQSPEKRLEWVAEISSGGRYIYYSDTVTGRFTISRDNARNILH
LEMSSLRSEDTAMYYCARGEVRQRGFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTW
NSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRAAALEVLFQGPGSHHHHHHHH
HH
;
;EVQLVESGGGLVKPGGSLKLSCAASGFTFSSYAMSWVRQSPEKRLEWVAEISSGGRYIYYSDTVTGRFTISRDNARNILH
LEMSSLRSEDTAMYYCARGEVRQRGFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTW
NSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRAAALEVLFQGPGSHHHHHHHH
HH
;
H ? 
3 'polypeptide(L)' no no 
;ENVLTQSPAIMSTSPGEKVTMTCRASSSVGSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGSGTKLEMKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGV
LNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE
;
;ENVLTQSPAIMSTSPGEKVTMTCRASSSVGSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGSGTKLEMKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGV
LNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE
;
L ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        'CHLORIDE ION' 
_pdbx_entity_nonpoly.comp_id     CL 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   THR n 
1 3   ALA n 
1 4   GLU n 
1 5   LYS n 
1 6   ALA n 
1 7   LEU n 
1 8   PRO n 
1 9   LEU n 
1 10  GLY n 
1 11  ASN n 
1 12  GLY n 
1 13  LYS n 
1 14  ALA n 
1 15  ALA n 
1 16  GLU n 
1 17  GLU n 
1 18  ALA n 
1 19  ARG n 
1 20  GLU n 
1 21  SER n 
1 22  GLU n 
1 23  ALA n 
1 24  PRO n 
1 25  GLY n 
1 26  GLY n 
1 27  GLY n 
1 28  CYS n 
1 29  SER n 
1 30  SER n 
1 31  GLY n 
1 32  GLY n 
1 33  ALA n 
1 34  ALA n 
1 35  PRO n 
1 36  ALA n 
1 37  ARG n 
1 38  HIS n 
1 39  PRO n 
1 40  ARG n 
1 41  VAL n 
1 42  LYS n 
1 43  ARG n 
1 44  ASP n 
1 45  LYS n 
1 46  ALA n 
1 47  VAL n 
1 48  HIS n 
1 49  GLU n 
1 50  ARG n 
1 51  GLY n 
1 52  HIS n 
1 53  TRP n 
1 54  ASN n 
1 55  ASN n 
1 56  LYS n 
1 57  VAL n 
1 58  GLU n 
1 59  PHE n 
1 60  VAL n 
1 61  LEU n 
1 62  SER n 
1 63  VAL n 
1 64  ALA n 
1 65  GLY n 
1 66  GLU n 
1 67  ILE n 
1 68  ILE n 
1 69  GLY n 
1 70  LEU n 
1 71  GLY n 
1 72  ASN n 
1 73  VAL n 
1 74  TRP n 
1 75  ARG n 
1 76  PHE n 
1 77  PRO n 
1 78  TYR n 
1 79  LEU n 
1 80  CYS n 
1 81  TYR n 
1 82  LYS n 
1 83  ASN n 
1 84  GLY n 
1 85  GLY n 
1 86  GLY n 
1 87  ALA n 
1 88  PHE n 
1 89  LEU n 
1 90  ILE n 
1 91  PRO n 
1 92  TYR n 
1 93  VAL n 
1 94  VAL n 
1 95  PHE n 
1 96  PHE n 
1 97  ILE n 
1 98  CYS n 
1 99  CYS n 
1 100 GLY n 
1 101 ILE n 
1 102 PRO n 
1 103 VAL n 
1 104 PHE n 
1 105 PHE n 
1 106 LEU n 
1 107 GLU n 
1 108 THR n 
1 109 ALA n 
1 110 LEU n 
1 111 GLY n 
1 112 GLN n 
1 113 PHE n 
1 114 THR n 
1 115 SER n 
1 116 GLU n 
1 117 GLY n 
1 118 GLY n 
1 119 ILE n 
1 120 THR n 
1 121 CYS n 
1 122 TRP n 
1 123 ARG n 
1 124 LYS n 
1 125 VAL n 
1 126 CYS n 
1 127 PRO n 
1 128 LEU n 
1 129 PHE n 
1 130 GLU n 
1 131 GLY n 
1 132 ILE n 
1 133 GLY n 
1 134 TYR n 
1 135 ALA n 
1 136 THR n 
1 137 GLN n 
1 138 VAL n 
1 139 ILE n 
1 140 GLU n 
1 141 ALA n 
1 142 HIS n 
1 143 LEU n 
1 144 ASN n 
1 145 VAL n 
1 146 TYR n 
1 147 TYR n 
1 148 ILE n 
1 149 ILE n 
1 150 ILE n 
1 151 LEU n 
1 152 ALA n 
1 153 TRP n 
1 154 ALA n 
1 155 ILE n 
1 156 PHE n 
1 157 TYR n 
1 158 LEU n 
1 159 SER n 
1 160 ASN n 
1 161 CYS n 
1 162 PHE n 
1 163 THR n 
1 164 THR n 
1 165 GLU n 
1 166 LEU n 
1 167 PRO n 
1 168 TRP n 
1 169 ALA n 
1 170 THR n 
1 171 CYS n 
1 172 GLY n 
1 173 HIS n 
1 174 GLU n 
1 175 TRP n 
1 176 ASN n 
1 177 THR n 
1 178 GLU n 
1 179 ASN n 
1 180 CYS n 
1 181 VAL n 
1 182 GLU n 
1 183 PHE n 
1 184 GLN n 
1 185 LYS n 
1 186 LEU n 
1 187 ASN n 
1 188 VAL n 
1 189 SER n 
1 190 ASN n 
1 191 TYR n 
1 192 SER n 
1 193 HIS n 
1 194 VAL n 
1 195 SER n 
1 196 LEU n 
1 197 GLN n 
1 198 ASN n 
1 199 ALA n 
1 200 THR n 
1 201 SER n 
1 202 PRO n 
1 203 VAL n 
1 204 MET n 
1 205 GLU n 
1 206 PHE n 
1 207 TRP n 
1 208 GLU n 
1 209 HIS n 
1 210 ARG n 
1 211 VAL n 
1 212 LEU n 
1 213 ALA n 
1 214 ILE n 
1 215 SER n 
1 216 ASP n 
1 217 GLY n 
1 218 ILE n 
1 219 GLU n 
1 220 HIS n 
1 221 ILE n 
1 222 GLY n 
1 223 ASN n 
1 224 LEU n 
1 225 ARG n 
1 226 TRP n 
1 227 GLU n 
1 228 LEU n 
1 229 ALA n 
1 230 LEU n 
1 231 CYS n 
1 232 LEU n 
1 233 LEU n 
1 234 ALA n 
1 235 ALA n 
1 236 TRP n 
1 237 THR n 
1 238 ILE n 
1 239 CYS n 
1 240 TYR n 
1 241 PHE n 
1 242 CYS n 
1 243 ILE n 
1 244 TRP n 
1 245 LYS n 
1 246 GLY n 
1 247 THR n 
1 248 LYS n 
1 249 SER n 
1 250 THR n 
1 251 GLY n 
1 252 LYS n 
1 253 VAL n 
1 254 VAL n 
1 255 TYR n 
1 256 VAL n 
1 257 THR n 
1 258 ALA n 
1 259 THR n 
1 260 PHE n 
1 261 PRO n 
1 262 TYR n 
1 263 ILE n 
1 264 MET n 
1 265 LEU n 
1 266 LEU n 
1 267 ILE n 
1 268 LEU n 
1 269 LEU n 
1 270 ILE n 
1 271 ARG n 
1 272 GLY n 
1 273 VAL n 
1 274 THR n 
1 275 LEU n 
1 276 PRO n 
1 277 GLY n 
1 278 ALA n 
1 279 SER n 
1 280 GLU n 
1 281 GLY n 
1 282 ILE n 
1 283 LYS n 
1 284 PHE n 
1 285 TYR n 
1 286 LEU n 
1 287 TYR n 
1 288 PRO n 
1 289 ASP n 
1 290 LEU n 
1 291 SER n 
1 292 ARG n 
1 293 LEU n 
1 294 SER n 
1 295 ASP n 
1 296 PRO n 
1 297 GLN n 
1 298 VAL n 
1 299 TRP n 
1 300 VAL n 
1 301 ASP n 
1 302 ALA n 
1 303 GLY n 
1 304 THR n 
1 305 GLN n 
1 306 ILE n 
1 307 PHE n 
1 308 PHE n 
1 309 SER n 
1 310 TYR n 
1 311 ALA n 
1 312 ILE n 
1 313 CYS n 
1 314 LEU n 
1 315 GLY n 
1 316 CYS n 
1 317 LEU n 
1 318 THR n 
1 319 ALA n 
1 320 LEU n 
1 321 GLY n 
1 322 SER n 
1 323 TYR n 
1 324 ASN n 
1 325 ASN n 
1 326 TYR n 
1 327 HIS n 
1 328 ASN n 
1 329 ASN n 
1 330 CYS n 
1 331 TYR n 
1 332 ARG n 
1 333 ASP n 
1 334 CYS n 
1 335 ILE n 
1 336 MET n 
1 337 LEU n 
1 338 CYS n 
1 339 CYS n 
1 340 LEU n 
1 341 ASN n 
1 342 SER n 
1 343 GLY n 
1 344 THR n 
1 345 SER n 
1 346 PHE n 
1 347 VAL n 
1 348 ALA n 
1 349 GLY n 
1 350 PHE n 
1 351 ALA n 
1 352 ILE n 
1 353 PHE n 
1 354 SER n 
1 355 VAL n 
1 356 LEU n 
1 357 GLY n 
1 358 PHE n 
1 359 MET n 
1 360 ALA n 
1 361 TYR n 
1 362 GLU n 
1 363 GLN n 
1 364 GLY n 
1 365 VAL n 
1 366 PRO n 
1 367 ILE n 
1 368 ALA n 
1 369 GLU n 
1 370 VAL n 
1 371 ALA n 
1 372 GLU n 
1 373 SER n 
1 374 GLY n 
1 375 PRO n 
1 376 GLY n 
1 377 LEU n 
1 378 ALA n 
1 379 PHE n 
1 380 ILE n 
1 381 ALA n 
1 382 TYR n 
1 383 PRO n 
1 384 LYS n 
1 385 ALA n 
1 386 VAL n 
1 387 THR n 
1 388 MET n 
1 389 MET n 
1 390 PRO n 
1 391 LEU n 
1 392 SER n 
1 393 PRO n 
1 394 LEU n 
1 395 TRP n 
1 396 ALA n 
1 397 THR n 
1 398 LEU n 
1 399 PHE n 
1 400 PHE n 
1 401 MET n 
1 402 MET n 
1 403 LEU n 
1 404 ILE n 
1 405 PHE n 
1 406 LEU n 
1 407 GLY n 
1 408 LEU n 
1 409 ASP n 
1 410 SER n 
1 411 GLN n 
1 412 PHE n 
1 413 VAL n 
1 414 CYS n 
1 415 VAL n 
1 416 GLU n 
1 417 SER n 
1 418 LEU n 
1 419 VAL n 
1 420 THR n 
1 421 ALA n 
1 422 VAL n 
1 423 VAL n 
1 424 ASP n 
1 425 MET n 
1 426 TYR n 
1 427 PRO n 
1 428 LYS n 
1 429 VAL n 
1 430 PHE n 
1 431 ARG n 
1 432 ARG n 
1 433 GLY n 
1 434 TYR n 
1 435 ARG n 
1 436 ARG n 
1 437 GLU n 
1 438 LEU n 
1 439 LEU n 
1 440 ILE n 
1 441 LEU n 
1 442 ALA n 
1 443 LEU n 
1 444 SER n 
1 445 VAL n 
1 446 ILE n 
1 447 SER n 
1 448 TYR n 
1 449 PHE n 
1 450 LEU n 
1 451 GLY n 
1 452 LEU n 
1 453 VAL n 
1 454 MET n 
1 455 LEU n 
1 456 THR n 
1 457 GLU n 
1 458 GLY n 
1 459 GLY n 
1 460 MET n 
1 461 TYR n 
1 462 ILE n 
1 463 PHE n 
1 464 GLN n 
1 465 LEU n 
1 466 PHE n 
1 467 ASP n 
1 468 SER n 
1 469 TYR n 
1 470 ALA n 
1 471 ALA n 
1 472 SER n 
1 473 GLY n 
1 474 MET n 
1 475 CYS n 
1 476 LEU n 
1 477 LEU n 
1 478 PHE n 
1 479 VAL n 
1 480 ALA n 
1 481 ILE n 
1 482 PHE n 
1 483 GLU n 
1 484 CYS n 
1 485 ILE n 
1 486 CYS n 
1 487 ILE n 
1 488 GLY n 
1 489 TRP n 
1 490 VAL n 
1 491 TYR n 
1 492 GLY n 
1 493 SER n 
1 494 ASN n 
1 495 ARG n 
1 496 PHE n 
1 497 SER n 
1 498 GLU n 
1 499 ASP n 
1 500 ILE n 
1 501 ARG n 
1 502 ASP n 
1 503 MET n 
1 504 ILE n 
1 505 GLY n 
1 506 PHE n 
1 507 PRO n 
1 508 PRO n 
1 509 PRO n 
1 510 SER n 
1 511 LEU n 
1 512 ILE n 
1 513 LYS n 
1 514 TRP n 
1 515 CYS n 
1 516 TRP n 
1 517 MET n 
1 518 ILE n 
1 519 MET n 
1 520 THR n 
1 521 PRO n 
1 522 GLY n 
1 523 ILE n 
1 524 CYS n 
1 525 ALA n 
1 526 GLY n 
1 527 ILE n 
1 528 PHE n 
1 529 ILE n 
1 530 PHE n 
1 531 PHE n 
1 532 LEU n 
1 533 ILE n 
1 534 LYS n 
1 535 TYR n 
1 536 LYS n 
1 537 PRO n 
1 538 LEU n 
1 539 LYS n 
1 540 TYR n 
1 541 ASN n 
1 542 ASN n 
1 543 ILE n 
1 544 TYR n 
1 545 THR n 
1 546 TYR n 
1 547 PRO n 
1 548 ALA n 
1 549 TRP n 
1 550 GLY n 
1 551 TYR n 
1 552 GLY n 
1 553 ILE n 
1 554 GLY n 
1 555 TRP n 
1 556 LEU n 
1 557 MET n 
1 558 ALA n 
1 559 LEU n 
1 560 SER n 
1 561 SER n 
1 562 MET n 
1 563 LEU n 
1 564 CYS n 
1 565 ILE n 
1 566 PRO n 
1 567 LEU n 
1 568 TRP n 
1 569 ILE n 
1 570 CYS n 
1 571 ILE n 
1 572 THR n 
1 573 VAL n 
1 574 TRP n 
1 575 LYS n 
1 576 THR n 
1 577 GLU n 
1 578 GLY n 
1 579 THR n 
1 580 LEU n 
1 581 PRO n 
1 582 GLU n 
1 583 LYS n 
1 584 LEU n 
1 585 GLN n 
1 586 LYS n 
1 587 LEU n 
1 588 THR n 
1 589 THR n 
1 590 PRO n 
1 591 SER n 
1 592 THR n 
1 593 ASP n 
1 594 LEU n 
1 595 LYS n 
1 596 MET n 
1 597 ARG n 
1 598 GLY n 
1 599 LYS n 
1 600 LEU n 
1 601 GLY n 
1 602 VAL n 
1 603 SER n 
1 604 PRO n 
1 605 ARG n 
1 606 MET n 
1 607 VAL n 
1 608 THR n 
1 609 VAL n 
1 610 ASN n 
1 611 ASP n 
1 612 CYS n 
1 613 ASP n 
1 614 ALA n 
1 615 LYS n 
1 616 LEU n 
1 617 LYS n 
1 618 SER n 
1 619 ASP n 
1 620 GLY n 
1 621 THR n 
1 622 ILE n 
1 623 ALA n 
1 624 ALA n 
1 625 ILE n 
1 626 THR n 
1 627 GLU n 
1 628 LYS n 
1 629 GLU n 
1 630 THR n 
1 631 HIS n 
1 632 PHE n 
1 633 ALA n 
1 634 ALA n 
1 635 ALA n 
1 636 LEU n 
1 637 GLU n 
1 638 VAL n 
1 639 LEU n 
1 640 PHE n 
1 641 GLN n 
2 1   GLU n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   VAL n 
2 6   GLU n 
2 7   SER n 
2 8   GLY n 
2 9   GLY n 
2 10  GLY n 
2 11  LEU n 
2 12  VAL n 
2 13  LYS n 
2 14  PRO n 
2 15  GLY n 
2 16  GLY n 
2 17  SER n 
2 18  LEU n 
2 19  LYS n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  ALA n 
2 24  ALA n 
2 25  SER n 
2 26  GLY n 
2 27  PHE n 
2 28  THR n 
2 29  PHE n 
2 30  SER n 
2 31  SER n 
2 32  TYR n 
2 33  ALA n 
2 34  MET n 
2 35  SER n 
2 36  TRP n 
2 37  VAL n 
2 38  ARG n 
2 39  GLN n 
2 40  SER n 
2 41  PRO n 
2 42  GLU n 
2 43  LYS n 
2 44  ARG n 
2 45  LEU n 
2 46  GLU n 
2 47  TRP n 
2 48  VAL n 
2 49  ALA n 
2 50  GLU n 
2 51  ILE n 
2 52  SER n 
2 53  SER n 
2 54  GLY n 
2 55  GLY n 
2 56  ARG n 
2 57  TYR n 
2 58  ILE n 
2 59  TYR n 
2 60  TYR n 
2 61  SER n 
2 62  ASP n 
2 63  THR n 
2 64  VAL n 
2 65  THR n 
2 66  GLY n 
2 67  ARG n 
2 68  PHE n 
2 69  THR n 
2 70  ILE n 
2 71  SER n 
2 72  ARG n 
2 73  ASP n 
2 74  ASN n 
2 75  ALA n 
2 76  ARG n 
2 77  ASN n 
2 78  ILE n 
2 79  LEU n 
2 80  HIS n 
2 81  LEU n 
2 82  GLU n 
2 83  MET n 
2 84  SER n 
2 85  SER n 
2 86  LEU n 
2 87  ARG n 
2 88  SER n 
2 89  GLU n 
2 90  ASP n 
2 91  THR n 
2 92  ALA n 
2 93  MET n 
2 94  TYR n 
2 95  TYR n 
2 96  CYS n 
2 97  ALA n 
2 98  ARG n 
2 99  GLY n 
2 100 GLU n 
2 101 VAL n 
2 102 ARG n 
2 103 GLN n 
2 104 ARG n 
2 105 GLY n 
2 106 PHE n 
2 107 ASP n 
2 108 TYR n 
2 109 TRP n 
2 110 GLY n 
2 111 GLN n 
2 112 GLY n 
2 113 THR n 
2 114 THR n 
2 115 LEU n 
2 116 THR n 
2 117 VAL n 
2 118 SER n 
2 119 SER n 
2 120 ALA n 
2 121 LYS n 
2 122 THR n 
2 123 THR n 
2 124 ALA n 
2 125 PRO n 
2 126 SER n 
2 127 VAL n 
2 128 TYR n 
2 129 PRO n 
2 130 LEU n 
2 131 ALA n 
2 132 PRO n 
2 133 VAL n 
2 134 CYS n 
2 135 GLY n 
2 136 ASP n 
2 137 THR n 
2 138 THR n 
2 139 GLY n 
2 140 SER n 
2 141 SER n 
2 142 VAL n 
2 143 THR n 
2 144 LEU n 
2 145 GLY n 
2 146 CYS n 
2 147 LEU n 
2 148 VAL n 
2 149 LYS n 
2 150 GLY n 
2 151 TYR n 
2 152 PHE n 
2 153 PRO n 
2 154 GLU n 
2 155 PRO n 
2 156 VAL n 
2 157 THR n 
2 158 LEU n 
2 159 THR n 
2 160 TRP n 
2 161 ASN n 
2 162 SER n 
2 163 GLY n 
2 164 SER n 
2 165 LEU n 
2 166 SER n 
2 167 SER n 
2 168 GLY n 
2 169 VAL n 
2 170 HIS n 
2 171 THR n 
2 172 PHE n 
2 173 PRO n 
2 174 ALA n 
2 175 VAL n 
2 176 LEU n 
2 177 GLN n 
2 178 SER n 
2 179 ASP n 
2 180 LEU n 
2 181 TYR n 
2 182 THR n 
2 183 LEU n 
2 184 SER n 
2 185 SER n 
2 186 SER n 
2 187 VAL n 
2 188 THR n 
2 189 VAL n 
2 190 THR n 
2 191 SER n 
2 192 SER n 
2 193 THR n 
2 194 TRP n 
2 195 PRO n 
2 196 SER n 
2 197 GLN n 
2 198 SER n 
2 199 ILE n 
2 200 THR n 
2 201 CYS n 
2 202 ASN n 
2 203 VAL n 
2 204 ALA n 
2 205 HIS n 
2 206 PRO n 
2 207 ALA n 
2 208 SER n 
2 209 SER n 
2 210 THR n 
2 211 LYS n 
2 212 VAL n 
2 213 ASP n 
2 214 LYS n 
2 215 LYS n 
2 216 ILE n 
2 217 GLU n 
2 218 PRO n 
2 219 ARG n 
2 220 ALA n 
2 221 ALA n 
2 222 ALA n 
2 223 LEU n 
2 224 GLU n 
2 225 VAL n 
2 226 LEU n 
2 227 PHE n 
2 228 GLN n 
2 229 GLY n 
2 230 PRO n 
2 231 GLY n 
2 232 SER n 
2 233 HIS n 
2 234 HIS n 
2 235 HIS n 
2 236 HIS n 
2 237 HIS n 
2 238 HIS n 
2 239 HIS n 
2 240 HIS n 
2 241 HIS n 
2 242 HIS n 
3 1   GLU n 
3 2   ASN n 
3 3   VAL n 
3 4   LEU n 
3 5   THR n 
3 6   GLN n 
3 7   SER n 
3 8   PRO n 
3 9   ALA n 
3 10  ILE n 
3 11  MET n 
3 12  SER n 
3 13  THR n 
3 14  SER n 
3 15  PRO n 
3 16  GLY n 
3 17  GLU n 
3 18  LYS n 
3 19  VAL n 
3 20  THR n 
3 21  MET n 
3 22  THR n 
3 23  CYS n 
3 24  ARG n 
3 25  ALA n 
3 26  SER n 
3 27  SER n 
3 28  SER n 
3 29  VAL n 
3 30  GLY n 
3 31  SER n 
3 32  SER n 
3 33  TYR n 
3 34  LEU n 
3 35  HIS n 
3 36  TRP n 
3 37  TYR n 
3 38  GLN n 
3 39  GLN n 
3 40  LYS n 
3 41  SER n 
3 42  GLY n 
3 43  ALA n 
3 44  SER n 
3 45  PRO n 
3 46  LYS n 
3 47  LEU n 
3 48  TRP n 
3 49  ILE n 
3 50  TYR n 
3 51  SER n 
3 52  THR n 
3 53  SER n 
3 54  ASN n 
3 55  LEU n 
3 56  ALA n 
3 57  SER n 
3 58  GLY n 
3 59  VAL n 
3 60  PRO n 
3 61  ALA n 
3 62  ARG n 
3 63  PHE n 
3 64  SER n 
3 65  GLY n 
3 66  SER n 
3 67  GLY n 
3 68  SER n 
3 69  GLY n 
3 70  THR n 
3 71  SER n 
3 72  TYR n 
3 73  SER n 
3 74  LEU n 
3 75  THR n 
3 76  ILE n 
3 77  SER n 
3 78  SER n 
3 79  VAL n 
3 80  GLU n 
3 81  ALA n 
3 82  GLU n 
3 83  ASP n 
3 84  ALA n 
3 85  ALA n 
3 86  THR n 
3 87  TYR n 
3 88  TYR n 
3 89  CYS n 
3 90  GLN n 
3 91  GLN n 
3 92  PHE n 
3 93  SER n 
3 94  GLY n 
3 95  TYR n 
3 96  PRO n 
3 97  LEU n 
3 98  THR n 
3 99  PHE n 
3 100 GLY n 
3 101 SER n 
3 102 GLY n 
3 103 THR n 
3 104 LYS n 
3 105 LEU n 
3 106 GLU n 
3 107 MET n 
3 108 LYS n 
3 109 ARG n 
3 110 ALA n 
3 111 ASP n 
3 112 ALA n 
3 113 ALA n 
3 114 PRO n 
3 115 THR n 
3 116 VAL n 
3 117 SER n 
3 118 ILE n 
3 119 PHE n 
3 120 PRO n 
3 121 PRO n 
3 122 SER n 
3 123 SER n 
3 124 GLU n 
3 125 GLN n 
3 126 LEU n 
3 127 THR n 
3 128 SER n 
3 129 GLY n 
3 130 GLY n 
3 131 ALA n 
3 132 SER n 
3 133 VAL n 
3 134 VAL n 
3 135 CYS n 
3 136 PHE n 
3 137 LEU n 
3 138 ASN n 
3 139 ASN n 
3 140 PHE n 
3 141 TYR n 
3 142 PRO n 
3 143 LYS n 
3 144 ASP n 
3 145 ILE n 
3 146 ASN n 
3 147 VAL n 
3 148 LYS n 
3 149 TRP n 
3 150 LYS n 
3 151 ILE n 
3 152 ASP n 
3 153 GLY n 
3 154 SER n 
3 155 GLU n 
3 156 ARG n 
3 157 GLN n 
3 158 ASN n 
3 159 GLY n 
3 160 VAL n 
3 161 LEU n 
3 162 ASN n 
3 163 SER n 
3 164 TRP n 
3 165 THR n 
3 166 ASP n 
3 167 GLN n 
3 168 ASP n 
3 169 SER n 
3 170 LYS n 
3 171 ASP n 
3 172 SER n 
3 173 THR n 
3 174 TYR n 
3 175 SER n 
3 176 MET n 
3 177 SER n 
3 178 SER n 
3 179 THR n 
3 180 LEU n 
3 181 THR n 
3 182 LEU n 
3 183 THR n 
3 184 LYS n 
3 185 ASP n 
3 186 GLU n 
3 187 TYR n 
3 188 GLU n 
3 189 ARG n 
3 190 HIS n 
3 191 ASN n 
3 192 SER n 
3 193 TYR n 
3 194 THR n 
3 195 CYS n 
3 196 GLU n 
3 197 ALA n 
3 198 THR n 
3 199 HIS n 
3 200 LYS n 
3 201 THR n 
3 202 SER n 
3 203 THR n 
3 204 SER n 
3 205 PRO n 
3 206 ILE n 
3 207 VAL n 
3 208 LYS n 
3 209 SER n 
3 210 PHE n 
3 211 ASN n 
3 212 ARG n 
3 213 ASN n 
3 214 GLU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 641 human ? 'SLC6A11, GABT3, GAT3' ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? human 
'Homo sapiens'          9606 ? ? ? ? ? ? ? ? 'HEK293S GnTI-' ? ? ? ? ? ? ? ? ? BacMam ? ? 
2 1 sample 'Biological sequence' 1 242 mouse ? ?                      ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ?     
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? Sf9             ? ? ? ? ? ? ? ? ? ?      ? ? 
3 1 sample 'Biological sequence' 1 214 mouse ? ?                      ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ?     
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? Sf9             ? ? ? ? ? ? ? ? ? ?      ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION'  ? 'Cl -1'          35.453  
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   THR 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   LYS 5   5   ?   ?   ?   A . n 
A 1 6   ALA 6   6   ?   ?   ?   A . n 
A 1 7   LEU 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   ?   ?   ?   A . n 
A 1 9   LEU 9   9   ?   ?   ?   A . n 
A 1 10  GLY 10  10  ?   ?   ?   A . n 
A 1 11  ASN 11  11  ?   ?   ?   A . n 
A 1 12  GLY 12  12  ?   ?   ?   A . n 
A 1 13  LYS 13  13  ?   ?   ?   A . n 
A 1 14  ALA 14  14  ?   ?   ?   A . n 
A 1 15  ALA 15  15  ?   ?   ?   A . n 
A 1 16  GLU 16  16  ?   ?   ?   A . n 
A 1 17  GLU 17  17  ?   ?   ?   A . n 
A 1 18  ALA 18  18  ?   ?   ?   A . n 
A 1 19  ARG 19  19  ?   ?   ?   A . n 
A 1 20  GLU 20  20  ?   ?   ?   A . n 
A 1 21  SER 21  21  ?   ?   ?   A . n 
A 1 22  GLU 22  22  ?   ?   ?   A . n 
A 1 23  ALA 23  23  ?   ?   ?   A . n 
A 1 24  PRO 24  24  ?   ?   ?   A . n 
A 1 25  GLY 25  25  ?   ?   ?   A . n 
A 1 26  GLY 26  26  ?   ?   ?   A . n 
A 1 27  GLY 27  27  ?   ?   ?   A . n 
A 1 28  CYS 28  28  ?   ?   ?   A . n 
A 1 29  SER 29  29  ?   ?   ?   A . n 
A 1 30  SER 30  30  ?   ?   ?   A . n 
A 1 31  GLY 31  31  ?   ?   ?   A . n 
A 1 32  GLY 32  32  ?   ?   ?   A . n 
A 1 33  ALA 33  33  ?   ?   ?   A . n 
A 1 34  ALA 34  34  ?   ?   ?   A . n 
A 1 35  PRO 35  35  ?   ?   ?   A . n 
A 1 36  ALA 36  36  ?   ?   ?   A . n 
A 1 37  ARG 37  37  ?   ?   ?   A . n 
A 1 38  HIS 38  38  ?   ?   ?   A . n 
A 1 39  PRO 39  39  ?   ?   ?   A . n 
A 1 40  ARG 40  40  ?   ?   ?   A . n 
A 1 41  VAL 41  41  ?   ?   ?   A . n 
A 1 42  LYS 42  42  ?   ?   ?   A . n 
A 1 43  ARG 43  43  ?   ?   ?   A . n 
A 1 44  ASP 44  44  ?   ?   ?   A . n 
A 1 45  LYS 45  45  ?   ?   ?   A . n 
A 1 46  ALA 46  46  ?   ?   ?   A . n 
A 1 47  VAL 47  47  ?   ?   ?   A . n 
A 1 48  HIS 48  48  ?   ?   ?   A . n 
A 1 49  GLU 49  49  ?   ?   ?   A . n 
A 1 50  ARG 50  50  ?   ?   ?   A . n 
A 1 51  GLY 51  51  ?   ?   ?   A . n 
A 1 52  HIS 52  52  ?   ?   ?   A . n 
A 1 53  TRP 53  53  ?   ?   ?   A . n 
A 1 54  ASN 54  54  ?   ?   ?   A . n 
A 1 55  ASN 55  55  ?   ?   ?   A . n 
A 1 56  LYS 56  56  ?   ?   ?   A . n 
A 1 57  VAL 57  57  57  VAL VAL A . n 
A 1 58  GLU 58  58  58  GLU GLU A . n 
A 1 59  PHE 59  59  59  PHE PHE A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  ALA 64  64  64  ALA ALA A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  GLU 66  66  66  GLU GLU A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  GLY 69  69  69  GLY GLY A . n 
A 1 70  LEU 70  70  70  LEU LEU A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  ASN 72  72  72  ASN ASN A . n 
A 1 73  VAL 73  73  73  VAL VAL A . n 
A 1 74  TRP 74  74  74  TRP TRP A . n 
A 1 75  ARG 75  75  75  ARG ARG A . n 
A 1 76  PHE 76  76  76  PHE PHE A . n 
A 1 77  PRO 77  77  77  PRO PRO A . n 
A 1 78  TYR 78  78  78  TYR TYR A . n 
A 1 79  LEU 79  79  79  LEU LEU A . n 
A 1 80  CYS 80  80  80  CYS CYS A . n 
A 1 81  TYR 81  81  81  TYR TYR A . n 
A 1 82  LYS 82  82  82  LYS LYS A . n 
A 1 83  ASN 83  83  83  ASN ASN A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  GLY 86  86  86  GLY GLY A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  PRO 91  91  91  PRO PRO A . n 
A 1 92  TYR 92  92  92  TYR TYR A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  VAL 94  94  94  VAL VAL A . n 
A 1 95  PHE 95  95  95  PHE PHE A . n 
A 1 96  PHE 96  96  96  PHE PHE A . n 
A 1 97  ILE 97  97  97  ILE ILE A . n 
A 1 98  CYS 98  98  98  CYS CYS A . n 
A 1 99  CYS 99  99  99  CYS CYS A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 ILE 101 101 101 ILE ILE A . n 
A 1 102 PRO 102 102 102 PRO PRO A . n 
A 1 103 VAL 103 103 103 VAL VAL A . n 
A 1 104 PHE 104 104 104 PHE PHE A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 THR 108 108 108 THR THR A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 GLY 111 111 111 GLY GLY A . n 
A 1 112 GLN 112 112 112 GLN GLN A . n 
A 1 113 PHE 113 113 113 PHE PHE A . n 
A 1 114 THR 114 114 114 THR THR A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 GLY 117 117 117 GLY GLY A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 ILE 119 119 119 ILE ILE A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 CYS 121 121 121 CYS CYS A . n 
A 1 122 TRP 122 122 122 TRP TRP A . n 
A 1 123 ARG 123 123 123 ARG ARG A . n 
A 1 124 LYS 124 124 124 LYS LYS A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 CYS 126 126 126 CYS CYS A . n 
A 1 127 PRO 127 127 127 PRO PRO A . n 
A 1 128 LEU 128 128 128 LEU LEU A . n 
A 1 129 PHE 129 129 129 PHE PHE A . n 
A 1 130 GLU 130 130 130 GLU GLU A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 ILE 132 132 132 ILE ILE A . n 
A 1 133 GLY 133 133 133 GLY GLY A . n 
A 1 134 TYR 134 134 134 TYR TYR A . n 
A 1 135 ALA 135 135 135 ALA ALA A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 GLN 137 137 137 GLN GLN A . n 
A 1 138 VAL 138 138 138 VAL VAL A . n 
A 1 139 ILE 139 139 139 ILE ILE A . n 
A 1 140 GLU 140 140 140 GLU GLU A . n 
A 1 141 ALA 141 141 141 ALA ALA A . n 
A 1 142 HIS 142 142 142 HIS HIS A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 ASN 144 144 144 ASN ASN A . n 
A 1 145 VAL 145 145 145 VAL VAL A . n 
A 1 146 TYR 146 146 146 TYR TYR A . n 
A 1 147 TYR 147 147 147 TYR TYR A . n 
A 1 148 ILE 148 148 148 ILE ILE A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 ILE 150 150 150 ILE ILE A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 ALA 152 152 152 ALA ALA A . n 
A 1 153 TRP 153 153 153 TRP TRP A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 ILE 155 155 155 ILE ILE A . n 
A 1 156 PHE 156 156 156 PHE PHE A . n 
A 1 157 TYR 157 157 157 TYR TYR A . n 
A 1 158 LEU 158 158 158 LEU LEU A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 ASN 160 160 160 ASN ASN A . n 
A 1 161 CYS 161 161 161 CYS CYS A . n 
A 1 162 PHE 162 162 162 PHE PHE A . n 
A 1 163 THR 163 163 163 THR THR A . n 
A 1 164 THR 164 164 164 THR THR A . n 
A 1 165 GLU 165 165 165 GLU GLU A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 PRO 167 167 167 PRO PRO A . n 
A 1 168 TRP 168 168 168 TRP TRP A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 THR 170 170 170 THR THR A . n 
A 1 171 CYS 171 171 171 CYS CYS A . n 
A 1 172 GLY 172 172 172 GLY GLY A . n 
A 1 173 HIS 173 173 173 HIS HIS A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 TRP 175 175 175 TRP TRP A . n 
A 1 176 ASN 176 176 176 ASN ASN A . n 
A 1 177 THR 177 177 177 THR THR A . n 
A 1 178 GLU 178 178 178 GLU GLU A . n 
A 1 179 ASN 179 179 179 ASN ASN A . n 
A 1 180 CYS 180 180 180 CYS CYS A . n 
A 1 181 VAL 181 181 181 VAL VAL A . n 
A 1 182 GLU 182 182 182 GLU GLU A . n 
A 1 183 PHE 183 183 183 PHE PHE A . n 
A 1 184 GLN 184 184 184 GLN GLN A . n 
A 1 185 LYS 185 185 185 LYS LYS A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 SER 189 189 189 SER SER A . n 
A 1 190 ASN 190 190 190 ASN ASN A . n 
A 1 191 TYR 191 191 191 TYR TYR A . n 
A 1 192 SER 192 192 192 SER SER A . n 
A 1 193 HIS 193 193 193 HIS HIS A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 SER 195 195 195 SER SER A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 GLN 197 197 197 GLN GLN A . n 
A 1 198 ASN 198 198 198 ASN ASN A . n 
A 1 199 ALA 199 199 199 ALA ALA A . n 
A 1 200 THR 200 200 200 THR THR A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 PRO 202 202 202 PRO PRO A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 MET 204 204 204 MET MET A . n 
A 1 205 GLU 205 205 205 GLU GLU A . n 
A 1 206 PHE 206 206 206 PHE PHE A . n 
A 1 207 TRP 207 207 207 TRP TRP A . n 
A 1 208 GLU 208 208 208 GLU GLU A . n 
A 1 209 HIS 209 209 209 HIS HIS A . n 
A 1 210 ARG 210 210 210 ARG ARG A . n 
A 1 211 VAL 211 211 211 VAL VAL A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 ALA 213 213 213 ALA ALA A . n 
A 1 214 ILE 214 214 214 ILE ILE A . n 
A 1 215 SER 215 215 215 SER SER A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 GLU 219 219 219 GLU GLU A . n 
A 1 220 HIS 220 220 220 HIS HIS A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 GLY 222 222 222 GLY GLY A . n 
A 1 223 ASN 223 223 223 ASN ASN A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 ARG 225 225 225 ARG ARG A . n 
A 1 226 TRP 226 226 226 TRP TRP A . n 
A 1 227 GLU 227 227 227 GLU GLU A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 ALA 229 229 229 ALA ALA A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 CYS 231 231 231 CYS CYS A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 TRP 236 236 236 TRP TRP A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 CYS 239 239 239 CYS CYS A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 PHE 241 241 241 PHE PHE A . n 
A 1 242 CYS 242 242 242 CYS CYS A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 TRP 244 244 244 TRP TRP A . n 
A 1 245 LYS 245 245 245 LYS LYS A . n 
A 1 246 GLY 246 246 246 GLY GLY A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 SER 249 249 249 SER SER A . n 
A 1 250 THR 250 250 250 THR THR A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 LYS 252 252 252 LYS LYS A . n 
A 1 253 VAL 253 253 253 VAL VAL A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 ALA 258 258 258 ALA ALA A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 PHE 260 260 260 PHE PHE A . n 
A 1 261 PRO 261 261 261 PRO PRO A . n 
A 1 262 TYR 262 262 262 TYR TYR A . n 
A 1 263 ILE 263 263 263 ILE ILE A . n 
A 1 264 MET 264 264 264 MET MET A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 ILE 267 267 267 ILE ILE A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 ILE 270 270 270 ILE ILE A . n 
A 1 271 ARG 271 271 271 ARG ARG A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 VAL 273 273 273 VAL VAL A . n 
A 1 274 THR 274 274 274 THR THR A . n 
A 1 275 LEU 275 275 275 LEU LEU A . n 
A 1 276 PRO 276 276 276 PRO PRO A . n 
A 1 277 GLY 277 277 277 GLY GLY A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 SER 279 279 279 SER SER A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 GLY 281 281 281 GLY GLY A . n 
A 1 282 ILE 282 282 282 ILE ILE A . n 
A 1 283 LYS 283 283 283 LYS LYS A . n 
A 1 284 PHE 284 284 284 PHE PHE A . n 
A 1 285 TYR 285 285 285 TYR TYR A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 TYR 287 287 287 TYR TYR A . n 
A 1 288 PRO 288 288 288 PRO PRO A . n 
A 1 289 ASP 289 289 289 ASP ASP A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 SER 291 291 291 SER SER A . n 
A 1 292 ARG 292 292 292 ARG ARG A . n 
A 1 293 LEU 293 293 293 LEU LEU A . n 
A 1 294 SER 294 294 294 SER SER A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 PRO 296 296 296 PRO PRO A . n 
A 1 297 GLN 297 297 297 GLN GLN A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 TRP 299 299 299 TRP TRP A . n 
A 1 300 VAL 300 300 300 VAL VAL A . n 
A 1 301 ASP 301 301 301 ASP ASP A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 GLY 303 303 303 GLY GLY A . n 
A 1 304 THR 304 304 304 THR THR A . n 
A 1 305 GLN 305 305 305 GLN GLN A . n 
A 1 306 ILE 306 306 306 ILE ILE A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 PHE 308 308 308 PHE PHE A . n 
A 1 309 SER 309 309 309 SER SER A . n 
A 1 310 TYR 310 310 310 TYR TYR A . n 
A 1 311 ALA 311 311 311 ALA ALA A . n 
A 1 312 ILE 312 312 312 ILE ILE A . n 
A 1 313 CYS 313 313 313 CYS CYS A . n 
A 1 314 LEU 314 314 314 LEU LEU A . n 
A 1 315 GLY 315 315 315 GLY GLY A . n 
A 1 316 CYS 316 316 316 CYS CYS A . n 
A 1 317 LEU 317 317 317 LEU LEU A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 LEU 320 320 320 LEU LEU A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 TYR 323 323 323 TYR TYR A . n 
A 1 324 ASN 324 324 324 ASN ASN A . n 
A 1 325 ASN 325 325 325 ASN ASN A . n 
A 1 326 TYR 326 326 326 TYR TYR A . n 
A 1 327 HIS 327 327 327 HIS HIS A . n 
A 1 328 ASN 328 328 328 ASN ASN A . n 
A 1 329 ASN 329 329 329 ASN ASN A . n 
A 1 330 CYS 330 330 330 CYS CYS A . n 
A 1 331 TYR 331 331 331 TYR TYR A . n 
A 1 332 ARG 332 332 332 ARG ARG A . n 
A 1 333 ASP 333 333 333 ASP ASP A . n 
A 1 334 CYS 334 334 334 CYS CYS A . n 
A 1 335 ILE 335 335 335 ILE ILE A . n 
A 1 336 MET 336 336 336 MET MET A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 CYS 338 338 338 CYS CYS A . n 
A 1 339 CYS 339 339 339 CYS CYS A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 ASN 341 341 341 ASN ASN A . n 
A 1 342 SER 342 342 342 SER SER A . n 
A 1 343 GLY 343 343 343 GLY GLY A . n 
A 1 344 THR 344 344 344 THR THR A . n 
A 1 345 SER 345 345 345 SER SER A . n 
A 1 346 PHE 346 346 346 PHE PHE A . n 
A 1 347 VAL 347 347 347 VAL VAL A . n 
A 1 348 ALA 348 348 348 ALA ALA A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 PHE 350 350 350 PHE PHE A . n 
A 1 351 ALA 351 351 351 ALA ALA A . n 
A 1 352 ILE 352 352 352 ILE ILE A . n 
A 1 353 PHE 353 353 353 PHE PHE A . n 
A 1 354 SER 354 354 354 SER SER A . n 
A 1 355 VAL 355 355 355 VAL VAL A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 GLY 357 357 357 GLY GLY A . n 
A 1 358 PHE 358 358 358 PHE PHE A . n 
A 1 359 MET 359 359 359 MET MET A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 TYR 361 361 361 TYR TYR A . n 
A 1 362 GLU 362 362 362 GLU GLU A . n 
A 1 363 GLN 363 363 363 GLN GLN A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 VAL 365 365 365 VAL VAL A . n 
A 1 366 PRO 366 366 366 PRO PRO A . n 
A 1 367 ILE 367 367 367 ILE ILE A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 GLU 369 369 369 GLU GLU A . n 
A 1 370 VAL 370 370 370 VAL VAL A . n 
A 1 371 ALA 371 371 371 ALA ALA A . n 
A 1 372 GLU 372 372 372 GLU GLU A . n 
A 1 373 SER 373 373 373 SER SER A . n 
A 1 374 GLY 374 374 374 GLY GLY A . n 
A 1 375 PRO 375 375 375 PRO PRO A . n 
A 1 376 GLY 376 376 376 GLY GLY A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 ALA 378 378 378 ALA ALA A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 ILE 380 380 380 ILE ILE A . n 
A 1 381 ALA 381 381 381 ALA ALA A . n 
A 1 382 TYR 382 382 382 TYR TYR A . n 
A 1 383 PRO 383 383 383 PRO PRO A . n 
A 1 384 LYS 384 384 384 LYS LYS A . n 
A 1 385 ALA 385 385 385 ALA ALA A . n 
A 1 386 VAL 386 386 386 VAL VAL A . n 
A 1 387 THR 387 387 387 THR THR A . n 
A 1 388 MET 388 388 388 MET MET A . n 
A 1 389 MET 389 389 389 MET MET A . n 
A 1 390 PRO 390 390 390 PRO PRO A . n 
A 1 391 LEU 391 391 391 LEU LEU A . n 
A 1 392 SER 392 392 392 SER SER A . n 
A 1 393 PRO 393 393 393 PRO PRO A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 TRP 395 395 395 TRP TRP A . n 
A 1 396 ALA 396 396 396 ALA ALA A . n 
A 1 397 THR 397 397 397 THR THR A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 PHE 399 399 399 PHE PHE A . n 
A 1 400 PHE 400 400 400 PHE PHE A . n 
A 1 401 MET 401 401 401 MET MET A . n 
A 1 402 MET 402 402 402 MET MET A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 ILE 404 404 404 ILE ILE A . n 
A 1 405 PHE 405 405 405 PHE PHE A . n 
A 1 406 LEU 406 406 406 LEU LEU A . n 
A 1 407 GLY 407 407 407 GLY GLY A . n 
A 1 408 LEU 408 408 408 LEU LEU A . n 
A 1 409 ASP 409 409 409 ASP ASP A . n 
A 1 410 SER 410 410 410 SER SER A . n 
A 1 411 GLN 411 411 411 GLN GLN A . n 
A 1 412 PHE 412 412 412 PHE PHE A . n 
A 1 413 VAL 413 413 413 VAL VAL A . n 
A 1 414 CYS 414 414 414 CYS CYS A . n 
A 1 415 VAL 415 415 415 VAL VAL A . n 
A 1 416 GLU 416 416 416 GLU GLU A . n 
A 1 417 SER 417 417 417 SER SER A . n 
A 1 418 LEU 418 418 418 LEU LEU A . n 
A 1 419 VAL 419 419 419 VAL VAL A . n 
A 1 420 THR 420 420 420 THR THR A . n 
A 1 421 ALA 421 421 421 ALA ALA A . n 
A 1 422 VAL 422 422 422 VAL VAL A . n 
A 1 423 VAL 423 423 423 VAL VAL A . n 
A 1 424 ASP 424 424 424 ASP ASP A . n 
A 1 425 MET 425 425 425 MET MET A . n 
A 1 426 TYR 426 426 426 TYR TYR A . n 
A 1 427 PRO 427 427 427 PRO PRO A . n 
A 1 428 LYS 428 428 428 LYS LYS A . n 
A 1 429 VAL 429 429 429 VAL VAL A . n 
A 1 430 PHE 430 430 430 PHE PHE A . n 
A 1 431 ARG 431 431 431 ARG ARG A . n 
A 1 432 ARG 432 432 432 ARG ARG A . n 
A 1 433 GLY 433 433 433 GLY GLY A . n 
A 1 434 TYR 434 434 434 TYR TYR A . n 
A 1 435 ARG 435 435 435 ARG ARG A . n 
A 1 436 ARG 436 436 436 ARG ARG A . n 
A 1 437 GLU 437 437 437 GLU GLU A . n 
A 1 438 LEU 438 438 438 LEU LEU A . n 
A 1 439 LEU 439 439 439 LEU LEU A . n 
A 1 440 ILE 440 440 440 ILE ILE A . n 
A 1 441 LEU 441 441 441 LEU LEU A . n 
A 1 442 ALA 442 442 442 ALA ALA A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 SER 444 444 444 SER SER A . n 
A 1 445 VAL 445 445 445 VAL VAL A . n 
A 1 446 ILE 446 446 446 ILE ILE A . n 
A 1 447 SER 447 447 447 SER SER A . n 
A 1 448 TYR 448 448 448 TYR TYR A . n 
A 1 449 PHE 449 449 449 PHE PHE A . n 
A 1 450 LEU 450 450 450 LEU LEU A . n 
A 1 451 GLY 451 451 451 GLY GLY A . n 
A 1 452 LEU 452 452 452 LEU LEU A . n 
A 1 453 VAL 453 453 453 VAL VAL A . n 
A 1 454 MET 454 454 454 MET MET A . n 
A 1 455 LEU 455 455 455 LEU LEU A . n 
A 1 456 THR 456 456 456 THR THR A . n 
A 1 457 GLU 457 457 457 GLU GLU A . n 
A 1 458 GLY 458 458 458 GLY GLY A . n 
A 1 459 GLY 459 459 459 GLY GLY A . n 
A 1 460 MET 460 460 460 MET MET A . n 
A 1 461 TYR 461 461 461 TYR TYR A . n 
A 1 462 ILE 462 462 462 ILE ILE A . n 
A 1 463 PHE 463 463 463 PHE PHE A . n 
A 1 464 GLN 464 464 464 GLN GLN A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 PHE 466 466 466 PHE PHE A . n 
A 1 467 ASP 467 467 467 ASP ASP A . n 
A 1 468 SER 468 468 468 SER SER A . n 
A 1 469 TYR 469 469 469 TYR TYR A . n 
A 1 470 ALA 470 470 470 ALA ALA A . n 
A 1 471 ALA 471 471 471 ALA ALA A . n 
A 1 472 SER 472 472 472 SER SER A . n 
A 1 473 GLY 473 473 473 GLY GLY A . n 
A 1 474 MET 474 474 474 MET MET A . n 
A 1 475 CYS 475 475 475 CYS CYS A . n 
A 1 476 LEU 476 476 476 LEU LEU A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 PHE 478 478 478 PHE PHE A . n 
A 1 479 VAL 479 479 479 VAL VAL A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 ILE 481 481 481 ILE ILE A . n 
A 1 482 PHE 482 482 482 PHE PHE A . n 
A 1 483 GLU 483 483 483 GLU GLU A . n 
A 1 484 CYS 484 484 484 CYS CYS A . n 
A 1 485 ILE 485 485 485 ILE ILE A . n 
A 1 486 CYS 486 486 486 CYS CYS A . n 
A 1 487 ILE 487 487 487 ILE ILE A . n 
A 1 488 GLY 488 488 488 GLY GLY A . n 
A 1 489 TRP 489 489 489 TRP TRP A . n 
A 1 490 VAL 490 490 490 VAL VAL A . n 
A 1 491 TYR 491 491 491 TYR TYR A . n 
A 1 492 GLY 492 492 492 GLY GLY A . n 
A 1 493 SER 493 493 493 SER SER A . n 
A 1 494 ASN 494 494 494 ASN ASN A . n 
A 1 495 ARG 495 495 495 ARG ARG A . n 
A 1 496 PHE 496 496 496 PHE PHE A . n 
A 1 497 SER 497 497 497 SER SER A . n 
A 1 498 GLU 498 498 498 GLU GLU A . n 
A 1 499 ASP 499 499 499 ASP ASP A . n 
A 1 500 ILE 500 500 500 ILE ILE A . n 
A 1 501 ARG 501 501 501 ARG ARG A . n 
A 1 502 ASP 502 502 502 ASP ASP A . n 
A 1 503 MET 503 503 503 MET MET A . n 
A 1 504 ILE 504 504 504 ILE ILE A . n 
A 1 505 GLY 505 505 505 GLY GLY A . n 
A 1 506 PHE 506 506 506 PHE PHE A . n 
A 1 507 PRO 507 507 507 PRO PRO A . n 
A 1 508 PRO 508 508 508 PRO PRO A . n 
A 1 509 PRO 509 509 509 PRO PRO A . n 
A 1 510 SER 510 510 510 SER SER A . n 
A 1 511 LEU 511 511 511 LEU LEU A . n 
A 1 512 ILE 512 512 512 ILE ILE A . n 
A 1 513 LYS 513 513 513 LYS LYS A . n 
A 1 514 TRP 514 514 514 TRP TRP A . n 
A 1 515 CYS 515 515 515 CYS CYS A . n 
A 1 516 TRP 516 516 516 TRP TRP A . n 
A 1 517 MET 517 517 517 MET MET A . n 
A 1 518 ILE 518 518 518 ILE ILE A . n 
A 1 519 MET 519 519 519 MET MET A . n 
A 1 520 THR 520 520 520 THR THR A . n 
A 1 521 PRO 521 521 521 PRO PRO A . n 
A 1 522 GLY 522 522 522 GLY GLY A . n 
A 1 523 ILE 523 523 523 ILE ILE A . n 
A 1 524 CYS 524 524 524 CYS CYS A . n 
A 1 525 ALA 525 525 525 ALA ALA A . n 
A 1 526 GLY 526 526 526 GLY GLY A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 PHE 528 528 528 PHE PHE A . n 
A 1 529 ILE 529 529 529 ILE ILE A . n 
A 1 530 PHE 530 530 530 PHE PHE A . n 
A 1 531 PHE 531 531 531 PHE PHE A . n 
A 1 532 LEU 532 532 532 LEU LEU A . n 
A 1 533 ILE 533 533 533 ILE ILE A . n 
A 1 534 LYS 534 534 534 LYS LYS A . n 
A 1 535 TYR 535 535 535 TYR TYR A . n 
A 1 536 LYS 536 536 536 LYS LYS A . n 
A 1 537 PRO 537 537 537 PRO PRO A . n 
A 1 538 LEU 538 538 538 LEU LEU A . n 
A 1 539 LYS 539 539 539 LYS LYS A . n 
A 1 540 TYR 540 540 540 TYR TYR A . n 
A 1 541 ASN 541 541 541 ASN ASN A . n 
A 1 542 ASN 542 542 542 ASN ASN A . n 
A 1 543 ILE 543 543 543 ILE ILE A . n 
A 1 544 TYR 544 544 544 TYR TYR A . n 
A 1 545 THR 545 545 545 THR THR A . n 
A 1 546 TYR 546 546 546 TYR TYR A . n 
A 1 547 PRO 547 547 547 PRO PRO A . n 
A 1 548 ALA 548 548 548 ALA ALA A . n 
A 1 549 TRP 549 549 549 TRP TRP A . n 
A 1 550 GLY 550 550 550 GLY GLY A . n 
A 1 551 TYR 551 551 551 TYR TYR A . n 
A 1 552 GLY 552 552 552 GLY GLY A . n 
A 1 553 ILE 553 553 553 ILE ILE A . n 
A 1 554 GLY 554 554 554 GLY GLY A . n 
A 1 555 TRP 555 555 555 TRP TRP A . n 
A 1 556 LEU 556 556 556 LEU LEU A . n 
A 1 557 MET 557 557 557 MET MET A . n 
A 1 558 ALA 558 558 558 ALA ALA A . n 
A 1 559 LEU 559 559 559 LEU LEU A . n 
A 1 560 SER 560 560 560 SER SER A . n 
A 1 561 SER 561 561 561 SER SER A . n 
A 1 562 MET 562 562 562 MET MET A . n 
A 1 563 LEU 563 563 563 LEU LEU A . n 
A 1 564 CYS 564 564 564 CYS CYS A . n 
A 1 565 ILE 565 565 565 ILE ILE A . n 
A 1 566 PRO 566 566 566 PRO PRO A . n 
A 1 567 LEU 567 567 567 LEU LEU A . n 
A 1 568 TRP 568 568 568 TRP TRP A . n 
A 1 569 ILE 569 569 569 ILE ILE A . n 
A 1 570 CYS 570 570 570 CYS CYS A . n 
A 1 571 ILE 571 571 571 ILE ILE A . n 
A 1 572 THR 572 572 572 THR THR A . n 
A 1 573 VAL 573 573 573 VAL VAL A . n 
A 1 574 TRP 574 574 574 TRP TRP A . n 
A 1 575 LYS 575 575 575 LYS LYS A . n 
A 1 576 THR 576 576 576 THR THR A . n 
A 1 577 GLU 577 577 577 GLU GLU A . n 
A 1 578 GLY 578 578 578 GLY GLY A . n 
A 1 579 THR 579 579 579 THR THR A . n 
A 1 580 LEU 580 580 580 LEU LEU A . n 
A 1 581 PRO 581 581 581 PRO PRO A . n 
A 1 582 GLU 582 582 582 GLU GLU A . n 
A 1 583 LYS 583 583 583 LYS LYS A . n 
A 1 584 LEU 584 584 584 LEU LEU A . n 
A 1 585 GLN 585 585 585 GLN GLN A . n 
A 1 586 LYS 586 586 586 LYS LYS A . n 
A 1 587 LEU 587 587 587 LEU LEU A . n 
A 1 588 THR 588 588 588 THR THR A . n 
A 1 589 THR 589 589 589 THR THR A . n 
A 1 590 PRO 590 590 590 PRO PRO A . n 
A 1 591 SER 591 591 591 SER SER A . n 
A 1 592 THR 592 592 592 THR THR A . n 
A 1 593 ASP 593 593 593 ASP ASP A . n 
A 1 594 LEU 594 594 594 LEU LEU A . n 
A 1 595 LYS 595 595 ?   ?   ?   A . n 
A 1 596 MET 596 596 ?   ?   ?   A . n 
A 1 597 ARG 597 597 ?   ?   ?   A . n 
A 1 598 GLY 598 598 ?   ?   ?   A . n 
A 1 599 LYS 599 599 ?   ?   ?   A . n 
A 1 600 LEU 600 600 ?   ?   ?   A . n 
A 1 601 GLY 601 601 ?   ?   ?   A . n 
A 1 602 VAL 602 602 ?   ?   ?   A . n 
A 1 603 SER 603 603 ?   ?   ?   A . n 
A 1 604 PRO 604 604 ?   ?   ?   A . n 
A 1 605 ARG 605 605 ?   ?   ?   A . n 
A 1 606 MET 606 606 ?   ?   ?   A . n 
A 1 607 VAL 607 607 ?   ?   ?   A . n 
A 1 608 THR 608 608 ?   ?   ?   A . n 
A 1 609 VAL 609 609 ?   ?   ?   A . n 
A 1 610 ASN 610 610 ?   ?   ?   A . n 
A 1 611 ASP 611 611 ?   ?   ?   A . n 
A 1 612 CYS 612 612 ?   ?   ?   A . n 
A 1 613 ASP 613 613 ?   ?   ?   A . n 
A 1 614 ALA 614 614 ?   ?   ?   A . n 
A 1 615 LYS 615 615 ?   ?   ?   A . n 
A 1 616 LEU 616 616 ?   ?   ?   A . n 
A 1 617 LYS 617 617 ?   ?   ?   A . n 
A 1 618 SER 618 618 ?   ?   ?   A . n 
A 1 619 ASP 619 619 ?   ?   ?   A . n 
A 1 620 GLY 620 620 ?   ?   ?   A . n 
A 1 621 THR 621 621 ?   ?   ?   A . n 
A 1 622 ILE 622 622 ?   ?   ?   A . n 
A 1 623 ALA 623 623 ?   ?   ?   A . n 
A 1 624 ALA 624 624 ?   ?   ?   A . n 
A 1 625 ILE 625 625 ?   ?   ?   A . n 
A 1 626 THR 626 626 ?   ?   ?   A . n 
A 1 627 GLU 627 627 ?   ?   ?   A . n 
A 1 628 LYS 628 628 ?   ?   ?   A . n 
A 1 629 GLU 629 629 ?   ?   ?   A . n 
A 1 630 THR 630 630 ?   ?   ?   A . n 
A 1 631 HIS 631 631 ?   ?   ?   A . n 
A 1 632 PHE 632 632 ?   ?   ?   A . n 
A 1 633 ALA 633 633 ?   ?   ?   A . n 
A 1 634 ALA 634 634 ?   ?   ?   A . n 
A 1 635 ALA 635 635 ?   ?   ?   A . n 
A 1 636 LEU 636 636 ?   ?   ?   A . n 
A 1 637 GLU 637 637 ?   ?   ?   A . n 
A 1 638 VAL 638 638 ?   ?   ?   A . n 
A 1 639 LEU 639 639 ?   ?   ?   A . n 
A 1 640 PHE 640 640 ?   ?   ?   A . n 
A 1 641 GLN 641 641 ?   ?   ?   A . n 
B 2 1   GLU 1   1   1   GLU GLU H . n 
B 2 2   VAL 2   2   2   VAL VAL H . n 
B 2 3   GLN 3   3   3   GLN GLN H . n 
B 2 4   LEU 4   4   4   LEU LEU H . n 
B 2 5   VAL 5   5   5   VAL VAL H . n 
B 2 6   GLU 6   6   6   GLU GLU H . n 
B 2 7   SER 7   7   7   SER SER H . n 
B 2 8   GLY 8   8   8   GLY GLY H . n 
B 2 9   GLY 9   9   9   GLY GLY H . n 
B 2 10  GLY 10  10  10  GLY GLY H . n 
B 2 11  LEU 11  11  11  LEU LEU H . n 
B 2 12  VAL 12  12  12  VAL VAL H . n 
B 2 13  LYS 13  13  13  LYS LYS H . n 
B 2 14  PRO 14  14  14  PRO PRO H . n 
B 2 15  GLY 15  15  15  GLY GLY H . n 
B 2 16  GLY 16  16  16  GLY GLY H . n 
B 2 17  SER 17  17  17  SER SER H . n 
B 2 18  LEU 18  18  18  LEU LEU H . n 
B 2 19  LYS 19  19  19  LYS LYS H . n 
B 2 20  LEU 20  20  20  LEU LEU H . n 
B 2 21  SER 21  21  21  SER SER H . n 
B 2 22  CYS 22  22  22  CYS CYS H . n 
B 2 23  ALA 23  23  23  ALA ALA H . n 
B 2 24  ALA 24  24  24  ALA ALA H . n 
B 2 25  SER 25  25  25  SER SER H . n 
B 2 26  GLY 26  26  26  GLY GLY H . n 
B 2 27  PHE 27  27  27  PHE PHE H . n 
B 2 28  THR 28  28  28  THR THR H . n 
B 2 29  PHE 29  29  29  PHE PHE H . n 
B 2 30  SER 30  30  30  SER SER H . n 
B 2 31  SER 31  31  31  SER SER H . n 
B 2 32  TYR 32  32  32  TYR TYR H . n 
B 2 33  ALA 33  33  33  ALA ALA H . n 
B 2 34  MET 34  34  34  MET MET H . n 
B 2 35  SER 35  35  35  SER SER H . n 
B 2 36  TRP 36  36  36  TRP TRP H . n 
B 2 37  VAL 37  37  37  VAL VAL H . n 
B 2 38  ARG 38  38  38  ARG ARG H . n 
B 2 39  GLN 39  39  39  GLN GLN H . n 
B 2 40  SER 40  40  40  SER SER H . n 
B 2 41  PRO 41  41  41  PRO PRO H . n 
B 2 42  GLU 42  42  42  GLU GLU H . n 
B 2 43  LYS 43  43  43  LYS LYS H . n 
B 2 44  ARG 44  44  44  ARG ARG H . n 
B 2 45  LEU 45  45  45  LEU LEU H . n 
B 2 46  GLU 46  46  46  GLU GLU H . n 
B 2 47  TRP 47  47  47  TRP TRP H . n 
B 2 48  VAL 48  48  48  VAL VAL H . n 
B 2 49  ALA 49  49  49  ALA ALA H . n 
B 2 50  GLU 50  50  50  GLU GLU H . n 
B 2 51  ILE 51  51  51  ILE ILE H . n 
B 2 52  SER 52  52  52  SER SER H . n 
B 2 53  SER 53  53  53  SER SER H . n 
B 2 54  GLY 54  54  54  GLY GLY H . n 
B 2 55  GLY 55  55  55  GLY GLY H . n 
B 2 56  ARG 56  56  56  ARG ARG H . n 
B 2 57  TYR 57  57  57  TYR TYR H . n 
B 2 58  ILE 58  58  58  ILE ILE H . n 
B 2 59  TYR 59  59  59  TYR TYR H . n 
B 2 60  TYR 60  60  60  TYR TYR H . n 
B 2 61  SER 61  61  61  SER SER H . n 
B 2 62  ASP 62  62  62  ASP ASP H . n 
B 2 63  THR 63  63  63  THR THR H . n 
B 2 64  VAL 64  64  64  VAL VAL H . n 
B 2 65  THR 65  65  65  THR THR H . n 
B 2 66  GLY 66  66  66  GLY GLY H . n 
B 2 67  ARG 67  67  67  ARG ARG H . n 
B 2 68  PHE 68  68  68  PHE PHE H . n 
B 2 69  THR 69  69  69  THR THR H . n 
B 2 70  ILE 70  70  70  ILE ILE H . n 
B 2 71  SER 71  71  71  SER SER H . n 
B 2 72  ARG 72  72  72  ARG ARG H . n 
B 2 73  ASP 73  73  73  ASP ASP H . n 
B 2 74  ASN 74  74  74  ASN ASN H . n 
B 2 75  ALA 75  75  75  ALA ALA H . n 
B 2 76  ARG 76  76  76  ARG ARG H . n 
B 2 77  ASN 77  77  77  ASN ASN H . n 
B 2 78  ILE 78  78  78  ILE ILE H . n 
B 2 79  LEU 79  79  79  LEU LEU H . n 
B 2 80  HIS 80  80  80  HIS HIS H . n 
B 2 81  LEU 81  81  81  LEU LEU H . n 
B 2 82  GLU 82  82  82  GLU GLU H . n 
B 2 83  MET 83  83  83  MET MET H . n 
B 2 84  SER 84  84  84  SER SER H . n 
B 2 85  SER 85  85  85  SER SER H . n 
B 2 86  LEU 86  86  86  LEU LEU H . n 
B 2 87  ARG 87  87  87  ARG ARG H . n 
B 2 88  SER 88  88  88  SER SER H . n 
B 2 89  GLU 89  89  89  GLU GLU H . n 
B 2 90  ASP 90  90  90  ASP ASP H . n 
B 2 91  THR 91  91  91  THR THR H . n 
B 2 92  ALA 92  92  92  ALA ALA H . n 
B 2 93  MET 93  93  93  MET MET H . n 
B 2 94  TYR 94  94  94  TYR TYR H . n 
B 2 95  TYR 95  95  95  TYR TYR H . n 
B 2 96  CYS 96  96  96  CYS CYS H . n 
B 2 97  ALA 97  97  97  ALA ALA H . n 
B 2 98  ARG 98  98  98  ARG ARG H . n 
B 2 99  GLY 99  99  99  GLY GLY H . n 
B 2 100 GLU 100 100 100 GLU GLU H . n 
B 2 101 VAL 101 101 101 VAL VAL H . n 
B 2 102 ARG 102 102 102 ARG ARG H . n 
B 2 103 GLN 103 103 103 GLN GLN H . n 
B 2 104 ARG 104 104 104 ARG ARG H . n 
B 2 105 GLY 105 105 105 GLY GLY H . n 
B 2 106 PHE 106 106 106 PHE PHE H . n 
B 2 107 ASP 107 107 107 ASP ASP H . n 
B 2 108 TYR 108 108 108 TYR TYR H . n 
B 2 109 TRP 109 109 109 TRP TRP H . n 
B 2 110 GLY 110 110 110 GLY GLY H . n 
B 2 111 GLN 111 111 111 GLN GLN H . n 
B 2 112 GLY 112 112 112 GLY GLY H . n 
B 2 113 THR 113 113 113 THR THR H . n 
B 2 114 THR 114 114 114 THR THR H . n 
B 2 115 LEU 115 115 115 LEU LEU H . n 
B 2 116 THR 116 116 116 THR THR H . n 
B 2 117 VAL 117 117 117 VAL VAL H . n 
B 2 118 SER 118 118 118 SER SER H . n 
B 2 119 SER 119 119 119 SER SER H . n 
B 2 120 ALA 120 120 120 ALA ALA H . n 
B 2 121 LYS 121 121 121 LYS LYS H . n 
B 2 122 THR 122 122 122 THR THR H . n 
B 2 123 THR 123 123 123 THR THR H . n 
B 2 124 ALA 124 124 124 ALA ALA H . n 
B 2 125 PRO 125 125 125 PRO PRO H . n 
B 2 126 SER 126 126 126 SER SER H . n 
B 2 127 VAL 127 127 127 VAL VAL H . n 
B 2 128 TYR 128 128 128 TYR TYR H . n 
B 2 129 PRO 129 129 129 PRO PRO H . n 
B 2 130 LEU 130 130 130 LEU LEU H . n 
B 2 131 ALA 131 131 131 ALA ALA H . n 
B 2 132 PRO 132 132 132 PRO PRO H . n 
B 2 133 VAL 133 133 133 VAL VAL H . n 
B 2 134 CYS 134 134 134 CYS CYS H . n 
B 2 135 GLY 135 135 ?   ?   ?   H . n 
B 2 136 ASP 136 136 ?   ?   ?   H . n 
B 2 137 THR 137 137 ?   ?   ?   H . n 
B 2 138 THR 138 138 ?   ?   ?   H . n 
B 2 139 GLY 139 139 139 GLY GLY H . n 
B 2 140 SER 140 140 140 SER SER H . n 
B 2 141 SER 141 141 141 SER SER H . n 
B 2 142 VAL 142 142 142 VAL VAL H . n 
B 2 143 THR 143 143 143 THR THR H . n 
B 2 144 LEU 144 144 144 LEU LEU H . n 
B 2 145 GLY 145 145 145 GLY GLY H . n 
B 2 146 CYS 146 146 146 CYS CYS H . n 
B 2 147 LEU 147 147 147 LEU LEU H . n 
B 2 148 VAL 148 148 148 VAL VAL H . n 
B 2 149 LYS 149 149 149 LYS LYS H . n 
B 2 150 GLY 150 150 150 GLY GLY H . n 
B 2 151 TYR 151 151 151 TYR TYR H . n 
B 2 152 PHE 152 152 152 PHE PHE H . n 
B 2 153 PRO 153 153 153 PRO PRO H . n 
B 2 154 GLU 154 154 154 GLU GLU H . n 
B 2 155 PRO 155 155 155 PRO PRO H . n 
B 2 156 VAL 156 156 156 VAL VAL H . n 
B 2 157 THR 157 157 157 THR THR H . n 
B 2 158 LEU 158 158 158 LEU LEU H . n 
B 2 159 THR 159 159 159 THR THR H . n 
B 2 160 TRP 160 160 160 TRP TRP H . n 
B 2 161 ASN 161 161 161 ASN ASN H . n 
B 2 162 SER 162 162 162 SER SER H . n 
B 2 163 GLY 163 163 163 GLY GLY H . n 
B 2 164 SER 164 164 164 SER SER H . n 
B 2 165 LEU 165 165 165 LEU LEU H . n 
B 2 166 SER 166 166 166 SER SER H . n 
B 2 167 SER 167 167 167 SER SER H . n 
B 2 168 GLY 168 168 168 GLY GLY H . n 
B 2 169 VAL 169 169 169 VAL VAL H . n 
B 2 170 HIS 170 170 170 HIS HIS H . n 
B 2 171 THR 171 171 171 THR THR H . n 
B 2 172 PHE 172 172 172 PHE PHE H . n 
B 2 173 PRO 173 173 173 PRO PRO H . n 
B 2 174 ALA 174 174 174 ALA ALA H . n 
B 2 175 VAL 175 175 175 VAL VAL H . n 
B 2 176 LEU 176 176 176 LEU LEU H . n 
B 2 177 GLN 177 177 177 GLN GLN H . n 
B 2 178 SER 178 178 178 SER SER H . n 
B 2 179 ASP 179 179 179 ASP ASP H . n 
B 2 180 LEU 180 180 180 LEU LEU H . n 
B 2 181 TYR 181 181 181 TYR TYR H . n 
B 2 182 THR 182 182 182 THR THR H . n 
B 2 183 LEU 183 183 183 LEU LEU H . n 
B 2 184 SER 184 184 184 SER SER H . n 
B 2 185 SER 185 185 185 SER SER H . n 
B 2 186 SER 186 186 186 SER SER H . n 
B 2 187 VAL 187 187 187 VAL VAL H . n 
B 2 188 THR 188 188 188 THR THR H . n 
B 2 189 VAL 189 189 189 VAL VAL H . n 
B 2 190 THR 190 190 190 THR THR H . n 
B 2 191 SER 191 191 191 SER SER H . n 
B 2 192 SER 192 192 192 SER SER H . n 
B 2 193 THR 193 193 193 THR THR H . n 
B 2 194 TRP 194 194 194 TRP TRP H . n 
B 2 195 PRO 195 195 195 PRO PRO H . n 
B 2 196 SER 196 196 196 SER SER H . n 
B 2 197 GLN 197 197 197 GLN GLN H . n 
B 2 198 SER 198 198 198 SER SER H . n 
B 2 199 ILE 199 199 199 ILE ILE H . n 
B 2 200 THR 200 200 200 THR THR H . n 
B 2 201 CYS 201 201 201 CYS CYS H . n 
B 2 202 ASN 202 202 202 ASN ASN H . n 
B 2 203 VAL 203 203 203 VAL VAL H . n 
B 2 204 ALA 204 204 204 ALA ALA H . n 
B 2 205 HIS 205 205 205 HIS HIS H . n 
B 2 206 PRO 206 206 206 PRO PRO H . n 
B 2 207 ALA 207 207 207 ALA ALA H . n 
B 2 208 SER 208 208 208 SER SER H . n 
B 2 209 SER 209 209 209 SER SER H . n 
B 2 210 THR 210 210 210 THR THR H . n 
B 2 211 LYS 211 211 211 LYS LYS H . n 
B 2 212 VAL 212 212 212 VAL VAL H . n 
B 2 213 ASP 213 213 213 ASP ASP H . n 
B 2 214 LYS 214 214 214 LYS LYS H . n 
B 2 215 LYS 215 215 215 LYS LYS H . n 
B 2 216 ILE 216 216 216 ILE ILE H . n 
B 2 217 GLU 217 217 217 GLU GLU H . n 
B 2 218 PRO 218 218 218 PRO PRO H . n 
B 2 219 ARG 219 219 219 ARG ARG H . n 
B 2 220 ALA 220 220 ?   ?   ?   H . n 
B 2 221 ALA 221 221 ?   ?   ?   H . n 
B 2 222 ALA 222 222 ?   ?   ?   H . n 
B 2 223 LEU 223 223 ?   ?   ?   H . n 
B 2 224 GLU 224 224 ?   ?   ?   H . n 
B 2 225 VAL 225 225 ?   ?   ?   H . n 
B 2 226 LEU 226 226 ?   ?   ?   H . n 
B 2 227 PHE 227 227 ?   ?   ?   H . n 
B 2 228 GLN 228 228 ?   ?   ?   H . n 
B 2 229 GLY 229 229 ?   ?   ?   H . n 
B 2 230 PRO 230 230 ?   ?   ?   H . n 
B 2 231 GLY 231 231 ?   ?   ?   H . n 
B 2 232 SER 232 232 ?   ?   ?   H . n 
B 2 233 HIS 233 233 ?   ?   ?   H . n 
B 2 234 HIS 234 234 ?   ?   ?   H . n 
B 2 235 HIS 235 235 ?   ?   ?   H . n 
B 2 236 HIS 236 236 ?   ?   ?   H . n 
B 2 237 HIS 237 237 ?   ?   ?   H . n 
B 2 238 HIS 238 238 ?   ?   ?   H . n 
B 2 239 HIS 239 239 ?   ?   ?   H . n 
B 2 240 HIS 240 240 ?   ?   ?   H . n 
B 2 241 HIS 241 241 ?   ?   ?   H . n 
B 2 242 HIS 242 242 ?   ?   ?   H . n 
C 3 1   GLU 1   1   1   GLU GLU L . n 
C 3 2   ASN 2   2   2   ASN ASN L . n 
C 3 3   VAL 3   3   3   VAL VAL L . n 
C 3 4   LEU 4   4   4   LEU LEU L . n 
C 3 5   THR 5   5   5   THR THR L . n 
C 3 6   GLN 6   6   6   GLN GLN L . n 
C 3 7   SER 7   7   7   SER SER L . n 
C 3 8   PRO 8   8   8   PRO PRO L . n 
C 3 9   ALA 9   9   9   ALA ALA L . n 
C 3 10  ILE 10  10  10  ILE ILE L . n 
C 3 11  MET 11  11  11  MET MET L . n 
C 3 12  SER 12  12  12  SER SER L . n 
C 3 13  THR 13  13  13  THR THR L . n 
C 3 14  SER 14  14  14  SER SER L . n 
C 3 15  PRO 15  15  15  PRO PRO L . n 
C 3 16  GLY 16  16  16  GLY GLY L . n 
C 3 17  GLU 17  17  17  GLU GLU L . n 
C 3 18  LYS 18  18  18  LYS LYS L . n 
C 3 19  VAL 19  19  19  VAL VAL L . n 
C 3 20  THR 20  20  20  THR THR L . n 
C 3 21  MET 21  21  21  MET MET L . n 
C 3 22  THR 22  22  22  THR THR L . n 
C 3 23  CYS 23  23  23  CYS CYS L . n 
C 3 24  ARG 24  24  24  ARG ARG L . n 
C 3 25  ALA 25  25  25  ALA ALA L . n 
C 3 26  SER 26  26  26  SER SER L . n 
C 3 27  SER 27  27  27  SER SER L . n 
C 3 28  SER 28  28  28  SER SER L . n 
C 3 29  VAL 29  29  29  VAL VAL L . n 
C 3 30  GLY 30  30  30  GLY GLY L . n 
C 3 31  SER 31  31  31  SER SER L . n 
C 3 32  SER 32  32  32  SER SER L . n 
C 3 33  TYR 33  33  33  TYR TYR L . n 
C 3 34  LEU 34  34  34  LEU LEU L . n 
C 3 35  HIS 35  35  35  HIS HIS L . n 
C 3 36  TRP 36  36  36  TRP TRP L . n 
C 3 37  TYR 37  37  37  TYR TYR L . n 
C 3 38  GLN 38  38  38  GLN GLN L . n 
C 3 39  GLN 39  39  39  GLN GLN L . n 
C 3 40  LYS 40  40  40  LYS LYS L . n 
C 3 41  SER 41  41  41  SER SER L . n 
C 3 42  GLY 42  42  42  GLY GLY L . n 
C 3 43  ALA 43  43  43  ALA ALA L . n 
C 3 44  SER 44  44  44  SER SER L . n 
C 3 45  PRO 45  45  45  PRO PRO L . n 
C 3 46  LYS 46  46  46  LYS LYS L . n 
C 3 47  LEU 47  47  47  LEU LEU L . n 
C 3 48  TRP 48  48  48  TRP TRP L . n 
C 3 49  ILE 49  49  49  ILE ILE L . n 
C 3 50  TYR 50  50  50  TYR TYR L . n 
C 3 51  SER 51  51  51  SER SER L . n 
C 3 52  THR 52  52  52  THR THR L . n 
C 3 53  SER 53  53  53  SER SER L . n 
C 3 54  ASN 54  54  54  ASN ASN L . n 
C 3 55  LEU 55  55  55  LEU LEU L . n 
C 3 56  ALA 56  56  56  ALA ALA L . n 
C 3 57  SER 57  57  57  SER SER L . n 
C 3 58  GLY 58  58  58  GLY GLY L . n 
C 3 59  VAL 59  59  59  VAL VAL L . n 
C 3 60  PRO 60  60  60  PRO PRO L . n 
C 3 61  ALA 61  61  61  ALA ALA L . n 
C 3 62  ARG 62  62  62  ARG ARG L . n 
C 3 63  PHE 63  63  63  PHE PHE L . n 
C 3 64  SER 64  64  64  SER SER L . n 
C 3 65  GLY 65  65  65  GLY GLY L . n 
C 3 66  SER 66  66  66  SER SER L . n 
C 3 67  GLY 67  67  67  GLY GLY L . n 
C 3 68  SER 68  68  68  SER SER L . n 
C 3 69  GLY 69  69  69  GLY GLY L . n 
C 3 70  THR 70  70  70  THR THR L . n 
C 3 71  SER 71  71  71  SER SER L . n 
C 3 72  TYR 72  72  72  TYR TYR L . n 
C 3 73  SER 73  73  73  SER SER L . n 
C 3 74  LEU 74  74  74  LEU LEU L . n 
C 3 75  THR 75  75  75  THR THR L . n 
C 3 76  ILE 76  76  76  ILE ILE L . n 
C 3 77  SER 77  77  77  SER SER L . n 
C 3 78  SER 78  78  78  SER SER L . n 
C 3 79  VAL 79  79  79  VAL VAL L . n 
C 3 80  GLU 80  80  80  GLU GLU L . n 
C 3 81  ALA 81  81  81  ALA ALA L . n 
C 3 82  GLU 82  82  82  GLU GLU L . n 
C 3 83  ASP 83  83  83  ASP ASP L . n 
C 3 84  ALA 84  84  84  ALA ALA L . n 
C 3 85  ALA 85  85  85  ALA ALA L . n 
C 3 86  THR 86  86  86  THR THR L . n 
C 3 87  TYR 87  87  87  TYR TYR L . n 
C 3 88  TYR 88  88  88  TYR TYR L . n 
C 3 89  CYS 89  89  89  CYS CYS L . n 
C 3 90  GLN 90  90  90  GLN GLN L . n 
C 3 91  GLN 91  91  91  GLN GLN L . n 
C 3 92  PHE 92  92  92  PHE PHE L . n 
C 3 93  SER 93  93  93  SER SER L . n 
C 3 94  GLY 94  94  94  GLY GLY L . n 
C 3 95  TYR 95  95  95  TYR TYR L . n 
C 3 96  PRO 96  96  96  PRO PRO L . n 
C 3 97  LEU 97  97  97  LEU LEU L . n 
C 3 98  THR 98  98  98  THR THR L . n 
C 3 99  PHE 99  99  99  PHE PHE L . n 
C 3 100 GLY 100 100 100 GLY GLY L . n 
C 3 101 SER 101 101 101 SER SER L . n 
C 3 102 GLY 102 102 102 GLY GLY L . n 
C 3 103 THR 103 103 103 THR THR L . n 
C 3 104 LYS 104 104 104 LYS LYS L . n 
C 3 105 LEU 105 105 105 LEU LEU L . n 
C 3 106 GLU 106 106 106 GLU GLU L . n 
C 3 107 MET 107 107 107 MET MET L . n 
C 3 108 LYS 108 108 108 LYS LYS L . n 
C 3 109 ARG 109 109 109 ARG ARG L . n 
C 3 110 ALA 110 110 110 ALA ALA L . n 
C 3 111 ASP 111 111 111 ASP ASP L . n 
C 3 112 ALA 112 112 112 ALA ALA L . n 
C 3 113 ALA 113 113 113 ALA ALA L . n 
C 3 114 PRO 114 114 114 PRO PRO L . n 
C 3 115 THR 115 115 115 THR THR L . n 
C 3 116 VAL 116 116 116 VAL VAL L . n 
C 3 117 SER 117 117 117 SER SER L . n 
C 3 118 ILE 118 118 118 ILE ILE L . n 
C 3 119 PHE 119 119 119 PHE PHE L . n 
C 3 120 PRO 120 120 120 PRO PRO L . n 
C 3 121 PRO 121 121 121 PRO PRO L . n 
C 3 122 SER 122 122 122 SER SER L . n 
C 3 123 SER 123 123 123 SER SER L . n 
C 3 124 GLU 124 124 124 GLU GLU L . n 
C 3 125 GLN 125 125 125 GLN GLN L . n 
C 3 126 LEU 126 126 126 LEU LEU L . n 
C 3 127 THR 127 127 127 THR THR L . n 
C 3 128 SER 128 128 128 SER SER L . n 
C 3 129 GLY 129 129 129 GLY GLY L . n 
C 3 130 GLY 130 130 130 GLY GLY L . n 
C 3 131 ALA 131 131 131 ALA ALA L . n 
C 3 132 SER 132 132 132 SER SER L . n 
C 3 133 VAL 133 133 133 VAL VAL L . n 
C 3 134 VAL 134 134 134 VAL VAL L . n 
C 3 135 CYS 135 135 135 CYS CYS L . n 
C 3 136 PHE 136 136 136 PHE PHE L . n 
C 3 137 LEU 137 137 137 LEU LEU L . n 
C 3 138 ASN 138 138 138 ASN ASN L . n 
C 3 139 ASN 139 139 139 ASN ASN L . n 
C 3 140 PHE 140 140 140 PHE PHE L . n 
C 3 141 TYR 141 141 141 TYR TYR L . n 
C 3 142 PRO 142 142 142 PRO PRO L . n 
C 3 143 LYS 143 143 143 LYS LYS L . n 
C 3 144 ASP 144 144 144 ASP ASP L . n 
C 3 145 ILE 145 145 145 ILE ILE L . n 
C 3 146 ASN 146 146 146 ASN ASN L . n 
C 3 147 VAL 147 147 147 VAL VAL L . n 
C 3 148 LYS 148 148 148 LYS LYS L . n 
C 3 149 TRP 149 149 149 TRP TRP L . n 
C 3 150 LYS 150 150 150 LYS LYS L . n 
C 3 151 ILE 151 151 151 ILE ILE L . n 
C 3 152 ASP 152 152 152 ASP ASP L . n 
C 3 153 GLY 153 153 153 GLY GLY L . n 
C 3 154 SER 154 154 154 SER SER L . n 
C 3 155 GLU 155 155 155 GLU GLU L . n 
C 3 156 ARG 156 156 156 ARG ARG L . n 
C 3 157 GLN 157 157 157 GLN GLN L . n 
C 3 158 ASN 158 158 158 ASN ASN L . n 
C 3 159 GLY 159 159 159 GLY GLY L . n 
C 3 160 VAL 160 160 160 VAL VAL L . n 
C 3 161 LEU 161 161 161 LEU LEU L . n 
C 3 162 ASN 162 162 162 ASN ASN L . n 
C 3 163 SER 163 163 163 SER SER L . n 
C 3 164 TRP 164 164 164 TRP TRP L . n 
C 3 165 THR 165 165 165 THR THR L . n 
C 3 166 ASP 166 166 166 ASP ASP L . n 
C 3 167 GLN 167 167 167 GLN GLN L . n 
C 3 168 ASP 168 168 168 ASP ASP L . n 
C 3 169 SER 169 169 169 SER SER L . n 
C 3 170 LYS 170 170 170 LYS LYS L . n 
C 3 171 ASP 171 171 171 ASP ASP L . n 
C 3 172 SER 172 172 172 SER SER L . n 
C 3 173 THR 173 173 173 THR THR L . n 
C 3 174 TYR 174 174 174 TYR TYR L . n 
C 3 175 SER 175 175 175 SER SER L . n 
C 3 176 MET 176 176 176 MET MET L . n 
C 3 177 SER 177 177 177 SER SER L . n 
C 3 178 SER 178 178 178 SER SER L . n 
C 3 179 THR 179 179 179 THR THR L . n 
C 3 180 LEU 180 180 180 LEU LEU L . n 
C 3 181 THR 181 181 181 THR THR L . n 
C 3 182 LEU 182 182 182 LEU LEU L . n 
C 3 183 THR 183 183 183 THR THR L . n 
C 3 184 LYS 184 184 184 LYS LYS L . n 
C 3 185 ASP 185 185 185 ASP ASP L . n 
C 3 186 GLU 186 186 186 GLU GLU L . n 
C 3 187 TYR 187 187 187 TYR TYR L . n 
C 3 188 GLU 188 188 188 GLU GLU L . n 
C 3 189 ARG 189 189 189 ARG ARG L . n 
C 3 190 HIS 190 190 190 HIS HIS L . n 
C 3 191 ASN 191 191 191 ASN ASN L . n 
C 3 192 SER 192 192 192 SER SER L . n 
C 3 193 TYR 193 193 193 TYR TYR L . n 
C 3 194 THR 194 194 194 THR THR L . n 
C 3 195 CYS 195 195 195 CYS CYS L . n 
C 3 196 GLU 196 196 196 GLU GLU L . n 
C 3 197 ALA 197 197 197 ALA ALA L . n 
C 3 198 THR 198 198 198 THR THR L . n 
C 3 199 HIS 199 199 199 HIS HIS L . n 
C 3 200 LYS 200 200 200 LYS LYS L . n 
C 3 201 THR 201 201 201 THR THR L . n 
C 3 202 SER 202 202 202 SER SER L . n 
C 3 203 THR 203 203 203 THR THR L . n 
C 3 204 SER 204 204 204 SER SER L . n 
C 3 205 PRO 205 205 205 PRO PRO L . n 
C 3 206 ILE 206 206 206 ILE ILE L . n 
C 3 207 VAL 207 207 207 VAL VAL L . n 
C 3 208 LYS 208 208 208 LYS LYS L . n 
C 3 209 SER 209 209 209 SER SER L . n 
C 3 210 PHE 210 210 210 PHE PHE L . n 
C 3 211 ASN 211 211 211 ASN ASN L . n 
C 3 212 ARG 212 212 212 ARG ARG L . n 
C 3 213 ASN 213 213 213 ASN ASN L . n 
C 3 214 GLU 214 214 ?   ?   ?   L . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        CL 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   CL 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         D 
_pdbx_nonpoly_scheme.entity_id       4 
_pdbx_nonpoly_scheme.mon_id          CL 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     800 
_pdbx_nonpoly_scheme.auth_seq_num    800 
_pdbx_nonpoly_scheme.pdb_mon_id      CL 
_pdbx_nonpoly_scheme.auth_mon_id     CL 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 431 ? CG  ? A ARG 431 CG  
2  1 Y 1 A ARG 431 ? CD  ? A ARG 431 CD  
3  1 Y 1 A ARG 431 ? NE  ? A ARG 431 NE  
4  1 Y 1 A ARG 431 ? CZ  ? A ARG 431 CZ  
5  1 Y 1 A ARG 431 ? NH1 ? A ARG 431 NH1 
6  1 Y 1 A ARG 431 ? NH2 ? A ARG 431 NH2 
7  1 Y 1 A GLU 582 ? CG  ? A GLU 582 CG  
8  1 Y 1 A GLU 582 ? CD  ? A GLU 582 CD  
9  1 Y 1 A GLU 582 ? OE1 ? A GLU 582 OE1 
10 1 Y 1 A GLU 582 ? OE2 ? A GLU 582 OE2 
11 1 Y 1 H GLU 1   ? CG  ? B GLU 1   CG  
12 1 Y 1 H GLU 1   ? CD  ? B GLU 1   CD  
13 1 Y 1 H GLU 1   ? OE1 ? B GLU 1   OE1 
14 1 Y 1 H GLU 1   ? OE2 ? B GLU 1   OE2 
15 1 Y 1 H GLN 3   ? CG  ? B GLN 3   CG  
16 1 Y 1 H GLN 3   ? CD  ? B GLN 3   CD  
17 1 Y 1 H GLN 3   ? OE1 ? B GLN 3   OE1 
18 1 Y 1 H GLN 3   ? NE2 ? B GLN 3   NE2 
19 1 Y 1 H SER 30  ? OG  ? B SER 30  OG  
20 1 Y 1 H GLN 111 ? CG  ? B GLN 111 CG  
21 1 Y 1 H GLN 111 ? CD  ? B GLN 111 CD  
22 1 Y 1 H GLN 111 ? OE1 ? B GLN 111 OE1 
23 1 Y 1 H GLN 111 ? NE2 ? B GLN 111 NE2 
24 1 Y 1 H ASP 179 ? CG  ? B ASP 179 CG  
25 1 Y 1 H ASP 179 ? OD1 ? B ASP 179 OD1 
26 1 Y 1 H ASP 179 ? OD2 ? B ASP 179 OD2 
27 1 Y 1 H VAL 189 ? CG1 ? B VAL 189 CG1 
28 1 Y 1 H VAL 189 ? CG2 ? B VAL 189 CG2 
29 1 Y 1 H SER 198 ? OG  ? B SER 198 OG  
30 1 Y 1 H LYS 215 ? CG  ? B LYS 215 CG  
31 1 Y 1 H LYS 215 ? CD  ? B LYS 215 CD  
32 1 Y 1 H LYS 215 ? CE  ? B LYS 215 CE  
33 1 Y 1 H LYS 215 ? NZ  ? B LYS 215 NZ  
34 1 Y 1 H GLU 217 ? CG  ? B GLU 217 CG  
35 1 Y 1 H GLU 217 ? CD  ? B GLU 217 CD  
36 1 Y 1 H GLU 217 ? OE1 ? B GLU 217 OE1 
37 1 Y 1 H GLU 217 ? OE2 ? B GLU 217 OE2 
38 1 Y 1 H ARG 219 ? CG  ? B ARG 219 CG  
39 1 Y 1 H ARG 219 ? CD  ? B ARG 219 CD  
40 1 Y 1 H ARG 219 ? NE  ? B ARG 219 NE  
41 1 Y 1 H ARG 219 ? CZ  ? B ARG 219 CZ  
42 1 Y 1 H ARG 219 ? NH1 ? B ARG 219 NH1 
43 1 Y 1 H ARG 219 ? NH2 ? B ARG 219 NH2 
44 1 Y 1 L GLU 82  ? CG  ? C GLU 82  CG  
45 1 Y 1 L GLU 82  ? CD  ? C GLU 82  CD  
46 1 Y 1 L GLU 82  ? OE1 ? C GLU 82  OE1 
47 1 Y 1 L GLU 82  ? OE2 ? C GLU 82  OE2 
48 1 Y 1 L SER 128 ? OG  ? C SER 128 OG  
49 1 Y 1 L ASP 152 ? CG  ? C ASP 152 CG  
50 1 Y 1 L ASP 152 ? OD1 ? C ASP 152 OD1 
51 1 Y 1 L ASP 152 ? OD2 ? C ASP 152 OD2 
52 1 Y 1 L SER 169 ? OG  ? C SER 169 OG  
53 1 Y 1 L LYS 184 ? CG  ? C LYS 184 CG  
54 1 Y 1 L LYS 184 ? CD  ? C LYS 184 CD  
55 1 Y 1 L LYS 184 ? CE  ? C LYS 184 CE  
56 1 Y 1 L LYS 184 ? NZ  ? C LYS 184 NZ  
57 1 Y 1 L ARG 189 ? CG  ? C ARG 189 CG  
58 1 Y 1 L ARG 189 ? CD  ? C ARG 189 CD  
59 1 Y 1 L ARG 189 ? NE  ? C ARG 189 NE  
60 1 Y 1 L ARG 189 ? CZ  ? C ARG 189 CZ  
61 1 Y 1 L ARG 189 ? NH1 ? C ARG 189 NH1 
62 1 Y 1 L ARG 189 ? NH2 ? C ARG 189 NH2 
63 1 Y 1 L ASN 191 ? CG  ? C ASN 191 CG  
64 1 Y 1 L ASN 191 ? OD1 ? C ASN 191 OD1 
65 1 Y 1 L ASN 191 ? ND2 ? C ASN 191 ND2 
66 1 Y 1 L SER 192 ? OG  ? C SER 192 OG  
67 1 Y 1 L ARG 212 ? CG  ? C ARG 212 CG  
68 1 Y 1 L ARG 212 ? CD  ? C ARG 212 CD  
69 1 Y 1 L ARG 212 ? NE  ? C ARG 212 NE  
70 1 Y 1 L ARG 212 ? CZ  ? C ARG 212 CZ  
71 1 Y 1 L ARG 212 ? NH1 ? C ARG 212 NH1 
72 1 Y 1 L ARG 212 ? NH2 ? C ARG 212 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CP5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CP5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CP5 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9CP5 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 7659  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.711 ? 10444 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.368 ? 1039  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.048 ? 1178  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1292  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9CP5 
_struct.title                        'Cryo-EM structure of human GAT3, apo state, inward-open conformation' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CP5 
_struct_keywords.text            
'GABA transporter 3, GAT3, SLC6, neurotransmitter transporter, NSS, cryo-EM, single particle, astrocyte, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP S6A11_HUMAN P48066 ? 1 
;MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLC
YKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSN
CFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY
FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTAL
GSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFF
MMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA
IFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALS
SMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
;
1 
2 PDB 9CP5        9CP5   ? 2 ? 1 
3 PDB 9CP5        9CP5   ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CP5 A 1 ? 632 ? P48066 1 ? 632 ? 1 632 
2 2 9CP5 H 1 ? 242 ? 9CP5   1 ? 242 ? 1 242 
3 3 9CP5 L 1 ? 214 ? 9CP5   1 ? 214 ? 1 214 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CP5 HIS A 327 ? UNP P48066 ASN 327 'engineered mutation' 327 1  
1 9CP5 SER A 497 ? UNP P48066 TYR 497 'engineered mutation' 497 2  
1 9CP5 GLU A 498 ? UNP P48066 ASP 498 'engineered mutation' 498 3  
1 9CP5 ASP A 499 ? UNP P48066 ASN 499 'engineered mutation' 499 4  
1 9CP5 ARG A 501 ? UNP P48066 GLU 501 'engineered mutation' 501 5  
1 9CP5 PHE A 506 ? UNP P48066 TYR 506 'engineered mutation' 506 6  
1 9CP5 PRO A 507 ? UNP P48066 ARG 507 'engineered mutation' 507 7  
1 9CP5 ALA A 633 ? UNP P48066 ?   ?   'expression tag'      633 8  
1 9CP5 ALA A 634 ? UNP P48066 ?   ?   'expression tag'      634 9  
1 9CP5 ALA A 635 ? UNP P48066 ?   ?   'expression tag'      635 10 
1 9CP5 LEU A 636 ? UNP P48066 ?   ?   'expression tag'      636 11 
1 9CP5 GLU A 637 ? UNP P48066 ?   ?   'expression tag'      637 12 
1 9CP5 VAL A 638 ? UNP P48066 ?   ?   'expression tag'      638 13 
1 9CP5 LEU A 639 ? UNP P48066 ?   ?   'expression tag'      639 14 
1 9CP5 PHE A 640 ? UNP P48066 ?   ?   'expression tag'      640 15 
1 9CP5 GLN A 641 ? UNP P48066 ?   ?   'expression tag'      641 16 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 57  ? ILE A 68  ? VAL A 57  ILE A 68  1 ? 12 
HELX_P HELX_P2  AA2 GLY A 69  ? TRP A 74  ? GLY A 69  TRP A 74  1 ? 6  
HELX_P HELX_P3  AA3 TRP A 74  ? ASN A 83  ? TRP A 74  ASN A 83  1 ? 10 
HELX_P HELX_P4  AA4 PHE A 88  ? CYS A 99  ? PHE A 88  CYS A 99  1 ? 12 
HELX_P HELX_P5  AA5 CYS A 99  ? SER A 115 ? CYS A 99  SER A 115 1 ? 17 
HELX_P HELX_P6  AA6 THR A 120 ? CYS A 126 ? THR A 120 CYS A 126 1 ? 7  
HELX_P HELX_P7  AA7 GLU A 130 ? TYR A 147 ? GLU A 130 TYR A 147 1 ? 18 
HELX_P HELX_P8  AA8 ILE A 148 ? PHE A 162 ? ILE A 148 PHE A 162 1 ? 15 
HELX_P HELX_P9  AA9 LEU A 166 ? THR A 170 ? LEU A 166 THR A 170 5 ? 5  
HELX_P HELX_P10 AB1 SER A 201 ? VAL A 211 ? SER A 201 VAL A 211 1 ? 11 
HELX_P HELX_P11 AB2 ARG A 225 ? LYS A 245 ? ARG A 225 LYS A 245 1 ? 21 
HELX_P HELX_P12 AB3 THR A 259 ? LEU A 275 ? THR A 259 LEU A 275 1 ? 17 
HELX_P HELX_P13 AB4 GLY A 277 ? TYR A 287 ? GLY A 277 TYR A 287 1 ? 11 
HELX_P HELX_P14 AB5 ASP A 295 ? TYR A 310 ? ASP A 295 TYR A 310 1 ? 16 
HELX_P HELX_P15 AB6 GLY A 315 ? ASN A 324 ? GLY A 315 ASN A 324 1 ? 10 
HELX_P HELX_P16 AB7 ASN A 329 ? GLN A 363 ? ASN A 329 GLN A 363 1 ? 35 
HELX_P HELX_P17 AB8 PRO A 366 ? VAL A 370 ? PRO A 366 VAL A 370 5 ? 5  
HELX_P HELX_P18 AB9 GLY A 376 ? PHE A 379 ? GLY A 376 PHE A 379 5 ? 4  
HELX_P HELX_P19 AC1 ILE A 380 ? VAL A 386 ? ILE A 380 VAL A 386 1 ? 7  
HELX_P HELX_P20 AC2 LEU A 391 ? TYR A 426 ? LEU A 391 TYR A 426 1 ? 36 
HELX_P HELX_P21 AC3 TYR A 426 ? ARG A 431 ? TYR A 426 ARG A 431 1 ? 6  
HELX_P HELX_P22 AC4 ARG A 435 ? LEU A 452 ? ARG A 435 LEU A 452 1 ? 18 
HELX_P HELX_P23 AC5 VAL A 453 ? LEU A 455 ? VAL A 453 LEU A 455 5 ? 3  
HELX_P HELX_P24 AC6 GLY A 458 ? ALA A 470 ? GLY A 458 ALA A 470 1 ? 13 
HELX_P HELX_P25 AC7 GLY A 473 ? VAL A 490 ? GLY A 473 VAL A 490 1 ? 18 
HELX_P HELX_P26 AC8 GLY A 492 ? GLY A 505 ? GLY A 492 GLY A 505 1 ? 14 
HELX_P HELX_P27 AC9 SER A 510 ? ILE A 518 ? SER A 510 ILE A 518 1 ? 9  
HELX_P HELX_P28 AD1 MET A 519 ? LYS A 534 ? MET A 519 LYS A 534 1 ? 16 
HELX_P HELX_P29 AD2 PRO A 547 ? LEU A 563 ? PRO A 547 LEU A 563 1 ? 17 
HELX_P HELX_P30 AD3 LEU A 563 ? THR A 576 ? LEU A 563 THR A 576 1 ? 14 
HELX_P HELX_P31 AD4 THR A 579 ? THR A 589 ? THR A 579 THR A 589 1 ? 11 
HELX_P HELX_P32 AD5 THR B 28  ? TYR B 32  ? THR H 28  TYR H 32  5 ? 5  
HELX_P HELX_P33 AD6 GLU C 80  ? ALA C 84  ? GLU L 80  ALA L 84  5 ? 5  
HELX_P HELX_P34 AD7 SER C 122 ? SER C 128 ? SER L 122 SER L 128 5 ? 7  
HELX_P HELX_P35 AD8 LYS C 184 ? ARG C 189 ? LYS L 184 ARG L 189 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 171 SG ? ? ? 1_555 A CYS 180 SG ? ? A CYS 171 A CYS 180 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ? ? B CYS 22  SG ? ? ? 1_555 B CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf3 disulf ? ? B CYS 146 SG ? ? ? 1_555 B CYS 201 SG ? ? H CYS 146 H CYS 201 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf4 disulf ? ? C CYS 23  SG ? ? ? 1_555 C CYS 89  SG ? ? L CYS 23  L CYS 89  1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf5 disulf ? ? C CYS 135 SG ? ? ? 1_555 C CYS 195 SG ? ? L CYS 135 L CYS 195 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 171 ? CYS A 180 ? CYS A 171 ? 1_555 CYS A 180 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 22  ? CYS B 96  ? CYS H 22  ? 1_555 CYS H 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 146 ? CYS B 201 ? CYS H 146 ? 1_555 CYS H 201 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS C 23  ? CYS C 89  ? CYS L 23  ? 1_555 CYS L 89  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS C 135 ? CYS C 195 ? CYS L 135 ? 1_555 CYS L 195 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 152 B . ? PHE 152 H PRO 153 B ? PRO 153 H 1 -4.91 
2 GLU 154 B . ? GLU 154 H PRO 155 B ? PRO 155 H 1 2.45  
3 TRP 194 B . ? TRP 194 H PRO 195 B ? PRO 195 H 1 0.90  
4 SER 7   C . ? SER 7   L PRO 8   C ? PRO 8   L 1 -5.32 
5 TYR 95  C . ? TYR 95  L PRO 96  C ? PRO 96  L 1 3.30  
6 TYR 141 C . ? TYR 141 L PRO 142 C ? PRO 142 L 1 -0.11 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN B 3   ? SER B 7   ? GLN H 3   SER H 7   
AA1 2 SER B 17  ? SER B 25  ? SER H 17  SER H 25  
AA1 3 ILE B 78  ? SER B 84  ? ILE H 78  SER H 84  
AA1 4 PHE B 68  ? ASP B 73  ? PHE H 68  ASP H 73  
AA2 1 LEU B 11  ? VAL B 12  ? LEU H 11  VAL H 12  
AA2 2 THR B 113 ? VAL B 117 ? THR H 113 VAL H 117 
AA2 3 ALA B 92  ? ALA B 97  ? ALA H 92  ALA H 97  
AA2 4 MET B 34  ? GLN B 39  ? MET H 34  GLN H 39  
AA2 5 LEU B 45  ? ILE B 51  ? LEU H 45  ILE H 51  
AA2 6 ILE B 58  ? TYR B 60  ? ILE H 58  TYR H 60  
AA3 1 SER B 126 ? LEU B 130 ? SER H 126 LEU H 130 
AA3 2 THR B 143 ? TYR B 151 ? THR H 143 TYR H 151 
AA3 3 LEU B 180 ? THR B 188 ? LEU H 180 THR H 188 
AA3 4 VAL B 169 ? THR B 171 ? VAL H 169 THR H 171 
AA4 1 SER B 126 ? LEU B 130 ? SER H 126 LEU H 130 
AA4 2 THR B 143 ? TYR B 151 ? THR H 143 TYR H 151 
AA4 3 LEU B 180 ? THR B 188 ? LEU H 180 THR H 188 
AA4 4 VAL B 175 ? GLN B 177 ? VAL H 175 GLN H 177 
AA5 1 THR B 157 ? TRP B 160 ? THR H 157 TRP H 160 
AA5 2 THR B 200 ? ALA B 204 ? THR H 200 ALA H 204 
AA5 3 ASP B 213 ? LYS B 215 ? ASP H 213 LYS H 215 
AA6 1 LEU C 4   ? THR C 5   ? LEU L 4   THR L 5   
AA6 2 VAL C 19  ? ALA C 25  ? VAL L 19  ALA L 25  
AA6 3 SER C 71  ? ILE C 76  ? SER L 71  ILE L 76  
AA6 4 PHE C 63  ? SER C 68  ? PHE L 63  SER L 68  
AA7 1 ILE C 10  ? SER C 12  ? ILE L 10  SER L 12  
AA7 2 THR C 103 ? GLU C 106 ? THR L 103 GLU L 106 
AA7 3 THR C 86  ? GLN C 91  ? THR L 86  GLN L 91  
AA7 4 LEU C 34  ? GLN C 39  ? LEU L 34  GLN L 39  
AA7 5 LYS C 46  ? ILE C 49  ? LYS L 46  ILE L 49  
AA8 1 SER C 117 ? PHE C 119 ? SER L 117 PHE L 119 
AA8 2 GLY C 130 ? PHE C 140 ? GLY L 130 PHE L 140 
AA8 3 TYR C 174 ? THR C 183 ? TYR L 174 THR L 183 
AA8 4 SER C 163 ? TRP C 164 ? SER L 163 TRP L 164 
AA9 1 SER C 154 ? ARG C 156 ? SER L 154 ARG L 156 
AA9 2 VAL C 147 ? ILE C 151 ? VAL L 147 ILE L 151 
AA9 3 SER C 192 ? ALA C 197 ? SER L 192 ALA L 197 
AA9 4 ILE C 206 ? ASN C 211 ? ILE L 206 ASN L 211 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER B 7   ? N SER H 7   O SER B 21  ? O SER H 21  
AA1 2 3 N CYS B 22  ? N CYS H 22  O LEU B 79  ? O LEU H 79  
AA1 3 4 O GLU B 82  ? O GLU H 82  N THR B 69  ? N THR H 69  
AA2 1 2 N VAL B 12  ? N VAL H 12  O THR B 116 ? O THR H 116 
AA2 2 3 O LEU B 115 ? O LEU H 115 N ALA B 92  ? N ALA H 92  
AA2 3 4 O TYR B 95  ? O TYR H 95  N VAL B 37  ? N VAL H 37  
AA2 4 5 N MET B 34  ? N MET H 34  O ILE B 51  ? O ILE H 51  
AA2 5 6 N GLU B 50  ? N GLU H 50  O TYR B 59  ? O TYR H 59  
AA3 1 2 N TYR B 128 ? N TYR H 128 O LEU B 147 ? O LEU H 147 
AA3 2 3 N VAL B 148 ? N VAL H 148 O LEU B 183 ? O LEU H 183 
AA3 3 4 O SER B 186 ? O SER H 186 N HIS B 170 ? N HIS H 170 
AA4 1 2 N TYR B 128 ? N TYR H 128 O LEU B 147 ? O LEU H 147 
AA4 2 3 N VAL B 148 ? N VAL H 148 O LEU B 183 ? O LEU H 183 
AA4 3 4 O LEU B 180 ? O LEU H 180 N GLN B 177 ? N GLN H 177 
AA5 1 2 N THR B 157 ? N THR H 157 O ALA B 204 ? O ALA H 204 
AA5 2 3 N CYS B 201 ? N CYS H 201 O LYS B 214 ? O LYS H 214 
AA6 1 2 N THR C 5   ? N THR L 5   O ARG C 24  ? O ARG L 24  
AA6 2 3 N MET C 21  ? N MET L 21  O LEU C 74  ? O LEU L 74  
AA6 3 4 O THR C 75  ? O THR L 75  N SER C 64  ? N SER L 64  
AA7 1 2 N MET C 11  ? N MET L 11  O GLU C 106 ? O GLU L 106 
AA7 2 3 O THR C 103 ? O THR L 103 N TYR C 87  ? N TYR L 87  
AA7 3 4 O THR C 86  ? O THR L 86  N GLN C 39  ? N GLN L 39  
AA7 4 5 N TRP C 36  ? N TRP L 36  O ILE C 49  ? O ILE L 49  
AA8 1 2 N PHE C 119 ? N PHE L 119 O VAL C 134 ? O VAL L 134 
AA8 2 3 N ALA C 131 ? N ALA L 131 O LEU C 182 ? O LEU L 182 
AA8 3 4 O SER C 177 ? O SER L 177 N SER C 163 ? N SER L 163 
AA9 1 2 O ARG C 156 ? O ARG L 156 N TRP C 149 ? N TRP L 149 
AA9 2 3 N LYS C 150 ? N LYS L 150 O THR C 194 ? O THR L 194 
AA9 3 4 N TYR C 193 ? N TYR L 193 O PHE C 210 ? O PHE L 210 
# 
_pdbx_entry_details.entry_id                   9CP5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 83  ? ? -94.71  49.83   
2  1 PHE A 129 ? ? -92.93  51.77   
3  1 TRP A 168 ? ? -96.80  31.83   
4  1 SER A 189 ? ? 53.63   -143.15 
5  1 SER A 192 ? ? 73.12   -5.01   
6  1 ASN A 198 ? ? 60.18   64.79   
7  1 ARG A 210 ? ? -130.67 -36.94  
8  1 THR A 250 ? ? 60.52   -173.71 
9  1 ALA A 471 ? ? -99.08  49.57   
10 1 SER A 510 ? ? 73.25   -10.95  
11 1 LYS A 534 ? ? -101.90 75.95   
12 1 ASN A 541 ? ? -94.86  45.70   
13 1 ASN A 542 ? ? 63.22   -12.08  
14 1 TYR A 544 ? ? -133.12 -38.26  
15 1 THR A 545 ? ? 57.03   70.03   
16 1 THR A 579 ? ? 66.37   164.07  
17 1 THR A 592 ? ? 58.02   -152.02 
18 1 THR H 159 ? ? -128.76 -168.95 
19 1 PRO H 195 ? ? -91.53  30.56   
20 1 THR L 52  ? ? 51.17   12.10   
21 1 SER L 53  ? ? -131.20 -38.51  
22 1 ASP L 152 ? ? 57.00   -95.58  
23 1 LYS L 170 ? ? -93.10  -60.78  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9CP5 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       'D_1000286001 structure' 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   Other 
_em_3d_fitting_list.type                          other 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    9CP5 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.51 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               158075 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human GABA transporter 3 in complex with 9D5' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        9CP5 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             3400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50.0 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   200 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9CP5 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9CP5 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A THR 2   ? A THR 2   
3   1 Y 1 A ALA 3   ? A ALA 3   
4   1 Y 1 A GLU 4   ? A GLU 4   
5   1 Y 1 A LYS 5   ? A LYS 5   
6   1 Y 1 A ALA 6   ? A ALA 6   
7   1 Y 1 A LEU 7   ? A LEU 7   
8   1 Y 1 A PRO 8   ? A PRO 8   
9   1 Y 1 A LEU 9   ? A LEU 9   
10  1 Y 1 A GLY 10  ? A GLY 10  
11  1 Y 1 A ASN 11  ? A ASN 11  
12  1 Y 1 A GLY 12  ? A GLY 12  
13  1 Y 1 A LYS 13  ? A LYS 13  
14  1 Y 1 A ALA 14  ? A ALA 14  
15  1 Y 1 A ALA 15  ? A ALA 15  
16  1 Y 1 A GLU 16  ? A GLU 16  
17  1 Y 1 A GLU 17  ? A GLU 17  
18  1 Y 1 A ALA 18  ? A ALA 18  
19  1 Y 1 A ARG 19  ? A ARG 19  
20  1 Y 1 A GLU 20  ? A GLU 20  
21  1 Y 1 A SER 21  ? A SER 21  
22  1 Y 1 A GLU 22  ? A GLU 22  
23  1 Y 1 A ALA 23  ? A ALA 23  
24  1 Y 1 A PRO 24  ? A PRO 24  
25  1 Y 1 A GLY 25  ? A GLY 25  
26  1 Y 1 A GLY 26  ? A GLY 26  
27  1 Y 1 A GLY 27  ? A GLY 27  
28  1 Y 1 A CYS 28  ? A CYS 28  
29  1 Y 1 A SER 29  ? A SER 29  
30  1 Y 1 A SER 30  ? A SER 30  
31  1 Y 1 A GLY 31  ? A GLY 31  
32  1 Y 1 A GLY 32  ? A GLY 32  
33  1 Y 1 A ALA 33  ? A ALA 33  
34  1 Y 1 A ALA 34  ? A ALA 34  
35  1 Y 1 A PRO 35  ? A PRO 35  
36  1 Y 1 A ALA 36  ? A ALA 36  
37  1 Y 1 A ARG 37  ? A ARG 37  
38  1 Y 1 A HIS 38  ? A HIS 38  
39  1 Y 1 A PRO 39  ? A PRO 39  
40  1 Y 1 A ARG 40  ? A ARG 40  
41  1 Y 1 A VAL 41  ? A VAL 41  
42  1 Y 1 A LYS 42  ? A LYS 42  
43  1 Y 1 A ARG 43  ? A ARG 43  
44  1 Y 1 A ASP 44  ? A ASP 44  
45  1 Y 1 A LYS 45  ? A LYS 45  
46  1 Y 1 A ALA 46  ? A ALA 46  
47  1 Y 1 A VAL 47  ? A VAL 47  
48  1 Y 1 A HIS 48  ? A HIS 48  
49  1 Y 1 A GLU 49  ? A GLU 49  
50  1 Y 1 A ARG 50  ? A ARG 50  
51  1 Y 1 A GLY 51  ? A GLY 51  
52  1 Y 1 A HIS 52  ? A HIS 52  
53  1 Y 1 A TRP 53  ? A TRP 53  
54  1 Y 1 A ASN 54  ? A ASN 54  
55  1 Y 1 A ASN 55  ? A ASN 55  
56  1 Y 1 A LYS 56  ? A LYS 56  
57  1 Y 1 A LYS 595 ? A LYS 595 
58  1 Y 1 A MET 596 ? A MET 596 
59  1 Y 1 A ARG 597 ? A ARG 597 
60  1 Y 1 A GLY 598 ? A GLY 598 
61  1 Y 1 A LYS 599 ? A LYS 599 
62  1 Y 1 A LEU 600 ? A LEU 600 
63  1 Y 1 A GLY 601 ? A GLY 601 
64  1 Y 1 A VAL 602 ? A VAL 602 
65  1 Y 1 A SER 603 ? A SER 603 
66  1 Y 1 A PRO 604 ? A PRO 604 
67  1 Y 1 A ARG 605 ? A ARG 605 
68  1 Y 1 A MET 606 ? A MET 606 
69  1 Y 1 A VAL 607 ? A VAL 607 
70  1 Y 1 A THR 608 ? A THR 608 
71  1 Y 1 A VAL 609 ? A VAL 609 
72  1 Y 1 A ASN 610 ? A ASN 610 
73  1 Y 1 A ASP 611 ? A ASP 611 
74  1 Y 1 A CYS 612 ? A CYS 612 
75  1 Y 1 A ASP 613 ? A ASP 613 
76  1 Y 1 A ALA 614 ? A ALA 614 
77  1 Y 1 A LYS 615 ? A LYS 615 
78  1 Y 1 A LEU 616 ? A LEU 616 
79  1 Y 1 A LYS 617 ? A LYS 617 
80  1 Y 1 A SER 618 ? A SER 618 
81  1 Y 1 A ASP 619 ? A ASP 619 
82  1 Y 1 A GLY 620 ? A GLY 620 
83  1 Y 1 A THR 621 ? A THR 621 
84  1 Y 1 A ILE 622 ? A ILE 622 
85  1 Y 1 A ALA 623 ? A ALA 623 
86  1 Y 1 A ALA 624 ? A ALA 624 
87  1 Y 1 A ILE 625 ? A ILE 625 
88  1 Y 1 A THR 626 ? A THR 626 
89  1 Y 1 A GLU 627 ? A GLU 627 
90  1 Y 1 A LYS 628 ? A LYS 628 
91  1 Y 1 A GLU 629 ? A GLU 629 
92  1 Y 1 A THR 630 ? A THR 630 
93  1 Y 1 A HIS 631 ? A HIS 631 
94  1 Y 1 A PHE 632 ? A PHE 632 
95  1 Y 1 A ALA 633 ? A ALA 633 
96  1 Y 1 A ALA 634 ? A ALA 634 
97  1 Y 1 A ALA 635 ? A ALA 635 
98  1 Y 1 A LEU 636 ? A LEU 636 
99  1 Y 1 A GLU 637 ? A GLU 637 
100 1 Y 1 A VAL 638 ? A VAL 638 
101 1 Y 1 A LEU 639 ? A LEU 639 
102 1 Y 1 A PHE 640 ? A PHE 640 
103 1 Y 1 A GLN 641 ? A GLN 641 
104 1 Y 1 H GLY 135 ? B GLY 135 
105 1 Y 1 H ASP 136 ? B ASP 136 
106 1 Y 1 H THR 137 ? B THR 137 
107 1 Y 1 H THR 138 ? B THR 138 
108 1 Y 1 H ALA 220 ? B ALA 220 
109 1 Y 1 H ALA 221 ? B ALA 221 
110 1 Y 1 H ALA 222 ? B ALA 222 
111 1 Y 1 H LEU 223 ? B LEU 223 
112 1 Y 1 H GLU 224 ? B GLU 224 
113 1 Y 1 H VAL 225 ? B VAL 225 
114 1 Y 1 H LEU 226 ? B LEU 226 
115 1 Y 1 H PHE 227 ? B PHE 227 
116 1 Y 1 H GLN 228 ? B GLN 228 
117 1 Y 1 H GLY 229 ? B GLY 229 
118 1 Y 1 H PRO 230 ? B PRO 230 
119 1 Y 1 H GLY 231 ? B GLY 231 
120 1 Y 1 H SER 232 ? B SER 232 
121 1 Y 1 H HIS 233 ? B HIS 233 
122 1 Y 1 H HIS 234 ? B HIS 234 
123 1 Y 1 H HIS 235 ? B HIS 235 
124 1 Y 1 H HIS 236 ? B HIS 236 
125 1 Y 1 H HIS 237 ? B HIS 237 
126 1 Y 1 H HIS 238 ? B HIS 238 
127 1 Y 1 H HIS 239 ? B HIS 239 
128 1 Y 1 H HIS 240 ? B HIS 240 
129 1 Y 1 H HIS 241 ? B HIS 241 
130 1 Y 1 H HIS 242 ? B HIS 242 
131 1 Y 1 L GLU 214 ? C GLU 214 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
ILE N    N  N N 159 
ILE CA   C  N S 160 
ILE C    C  N N 161 
ILE O    O  N N 162 
ILE CB   C  N S 163 
ILE CG1  C  N N 164 
ILE CG2  C  N N 165 
ILE CD1  C  N N 166 
ILE OXT  O  N N 167 
ILE H    H  N N 168 
ILE H2   H  N N 169 
ILE HA   H  N N 170 
ILE HB   H  N N 171 
ILE HG12 H  N N 172 
ILE HG13 H  N N 173 
ILE HG21 H  N N 174 
ILE HG22 H  N N 175 
ILE HG23 H  N N 176 
ILE HD11 H  N N 177 
ILE HD12 H  N N 178 
ILE HD13 H  N N 179 
ILE HXT  H  N N 180 
LEU N    N  N N 181 
LEU CA   C  N S 182 
LEU C    C  N N 183 
LEU O    O  N N 184 
LEU CB   C  N N 185 
LEU CG   C  N N 186 
LEU CD1  C  N N 187 
LEU CD2  C  N N 188 
LEU OXT  O  N N 189 
LEU H    H  N N 190 
LEU H2   H  N N 191 
LEU HA   H  N N 192 
LEU HB2  H  N N 193 
LEU HB3  H  N N 194 
LEU HG   H  N N 195 
LEU HD11 H  N N 196 
LEU HD12 H  N N 197 
LEU HD13 H  N N 198 
LEU HD21 H  N N 199 
LEU HD22 H  N N 200 
LEU HD23 H  N N 201 
LEU HXT  H  N N 202 
LYS N    N  N N 203 
LYS CA   C  N S 204 
LYS C    C  N N 205 
LYS O    O  N N 206 
LYS CB   C  N N 207 
LYS CG   C  N N 208 
LYS CD   C  N N 209 
LYS CE   C  N N 210 
LYS NZ   N  N N 211 
LYS OXT  O  N N 212 
LYS H    H  N N 213 
LYS H2   H  N N 214 
LYS HA   H  N N 215 
LYS HB2  H  N N 216 
LYS HB3  H  N N 217 
LYS HG2  H  N N 218 
LYS HG3  H  N N 219 
LYS HD2  H  N N 220 
LYS HD3  H  N N 221 
LYS HE2  H  N N 222 
LYS HE3  H  N N 223 
LYS HZ1  H  N N 224 
LYS HZ2  H  N N 225 
LYS HZ3  H  N N 226 
LYS HXT  H  N N 227 
MET N    N  N N 228 
MET CA   C  N S 229 
MET C    C  N N 230 
MET O    O  N N 231 
MET CB   C  N N 232 
MET CG   C  N N 233 
MET SD   S  N N 234 
MET CE   C  N N 235 
MET OXT  O  N N 236 
MET H    H  N N 237 
MET H2   H  N N 238 
MET HA   H  N N 239 
MET HB2  H  N N 240 
MET HB3  H  N N 241 
MET HG2  H  N N 242 
MET HG3  H  N N 243 
MET HE1  H  N N 244 
MET HE2  H  N N 245 
MET HE3  H  N N 246 
MET HXT  H  N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-17 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9CP5 
_em_admin.last_update        2025-05-07 
_em_admin.map_release_date   2025-05-07 
_em_admin.title              'Cryo-EM structure of human GAT3, apo state, inward-open conformation' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.111 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 'HEK293S GnTI-' 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              BacMam 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               1.8 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         52.5 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     9115 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   6319538 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? cryoSPARC       v4.5.3 
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU             ?      
MASKING                         ? 3  ? ? ? ?               ?      
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC       v4.5.3 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?               ?      
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?               ?      
'MODEL FITTING'                 ? 7  ? 1 ? 'UCSF ChimeraX' ?      
OTHER                           ? 8  ? ? ? ?               ?      
'INITIAL EULER ASSIGNMENT'      ? 9  1 ? ? cryoSPARC       v4.5.3 
'FINAL EULER ASSIGNMENT'        ? 10 1 ? ? cryoSPARC       v4.5.3 
CLASSIFICATION                  ? 11 1 ? ? cryoSPARC       v4.5.3 
RECONSTRUCTION                  ? 12 1 ? ? cryoSPARC       v4.5.3 
'MODEL REFINEMENT'              ? 13 ? 1 ? PHENIX          1.21.1 
'VOLUME SELECTION'              ? 14 1 1 1 ?               ?      
'SERIES ALIGNMENT'              ? 15 1 1 1 ?               ?      
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?               ?      
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?               ?      
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?               ?      
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?               ?      
# 
_em_specimen.concentration           3.274 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             other 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9CP5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . VAL A 1 57  ? 172.393 145.693 162.830 1.00 130.00 ? 57  VAL A N   1 
ATOM   2    C  CA  . VAL A 1 57  ? 172.690 146.851 161.998 1.00 130.00 ? 57  VAL A CA  1 
ATOM   3    C  C   . VAL A 1 57  ? 173.237 147.983 162.860 1.00 130.00 ? 57  VAL A C   1 
ATOM   4    O  O   . VAL A 1 57  ? 172.687 148.288 163.918 1.00 130.00 ? 57  VAL A O   1 
ATOM   5    C  CB  . VAL A 1 57  ? 171.446 147.306 161.215 1.00 130.00 ? 57  VAL A CB  1 
ATOM   6    C  CG1 . VAL A 1 57  ? 171.827 148.320 160.147 1.00 130.00 ? 57  VAL A CG1 1 
ATOM   7    C  CG2 . VAL A 1 57  ? 170.746 146.107 160.593 1.00 130.00 ? 57  VAL A CG2 1 
ATOM   8    N  N   . GLU A 1 58  ? 174.334 148.595 162.403 1.00 130.68 ? 58  GLU A N   1 
ATOM   9    C  CA  . GLU A 1 58  ? 174.937 149.694 163.149 1.00 130.68 ? 58  GLU A CA  1 
ATOM   10   C  C   . GLU A 1 58  ? 174.058 150.938 163.133 1.00 130.68 ? 58  GLU A C   1 
ATOM   11   O  O   . GLU A 1 58  ? 174.024 151.682 164.120 1.00 130.68 ? 58  GLU A O   1 
ATOM   12   C  CB  . GLU A 1 58  ? 176.317 150.026 162.580 1.00 130.68 ? 58  GLU A CB  1 
ATOM   13   C  CG  . GLU A 1 58  ? 177.290 148.861 162.571 1.00 130.68 ? 58  GLU A CG  1 
ATOM   14   C  CD  . GLU A 1 58  ? 177.378 148.192 161.214 1.00 130.68 ? 58  GLU A CD  1 
ATOM   15   O  OE1 . GLU A 1 58  ? 176.402 147.523 160.814 1.00 130.68 ? 58  GLU A OE1 1 
ATOM   16   O  OE2 . GLU A 1 58  ? 178.423 148.339 160.545 1.00 130.68 ? 58  GLU A OE2 1 
ATOM   17   N  N   . PHE A 1 59  ? 173.355 151.184 162.026 1.00 128.48 ? 59  PHE A N   1 
ATOM   18   C  CA  . PHE A 1 59  ? 172.515 152.373 161.926 1.00 128.48 ? 59  PHE A CA  1 
ATOM   19   C  C   . PHE A 1 59  ? 171.290 152.270 162.826 1.00 128.48 ? 59  PHE A C   1 
ATOM   20   O  O   . PHE A 1 59  ? 170.899 153.253 163.464 1.00 128.48 ? 59  PHE A O   1 
ATOM   21   C  CB  . PHE A 1 59  ? 172.094 152.596 160.475 1.00 128.48 ? 59  PHE A CB  1 
ATOM   22   C  CG  . PHE A 1 59  ? 171.417 153.914 160.236 1.00 128.48 ? 59  PHE A CG  1 
ATOM   23   C  CD1 . PHE A 1 59  ? 171.919 155.077 160.799 1.00 128.48 ? 59  PHE A CD1 1 
ATOM   24   C  CD2 . PHE A 1 59  ? 170.279 153.991 159.450 1.00 128.48 ? 59  PHE A CD2 1 
ATOM   25   C  CE1 . PHE A 1 59  ? 171.298 156.293 160.581 1.00 128.48 ? 59  PHE A CE1 1 
ATOM   26   C  CE2 . PHE A 1 59  ? 169.653 155.204 159.228 1.00 128.48 ? 59  PHE A CE2 1 
ATOM   27   C  CZ  . PHE A 1 59  ? 170.164 156.356 159.794 1.00 128.48 ? 59  PHE A CZ  1 
ATOM   28   N  N   . VAL A 1 60  ? 170.668 151.090 162.884 1.00 127.67 ? 60  VAL A N   1 
ATOM   29   C  CA  . VAL A 1 60  ? 169.468 150.916 163.697 1.00 127.67 ? 60  VAL A CA  1 
ATOM   30   C  C   . VAL A 1 60  ? 169.814 150.963 165.182 1.00 127.67 ? 60  VAL A C   1 
ATOM   31   O  O   . VAL A 1 60  ? 169.093 151.571 165.983 1.00 127.67 ? 60  VAL A O   1 
ATOM   32   C  CB  . VAL A 1 60  ? 168.761 149.603 163.314 1.00 127.67 ? 60  VAL A CB  1 
ATOM   33   C  CG1 . VAL A 1 60  ? 167.545 149.357 164.198 1.00 127.67 ? 60  VAL A CG1 1 
ATOM   34   C  CG2 . VAL A 1 60  ? 168.363 149.627 161.846 1.00 127.67 ? 60  VAL A CG2 1 
ATOM   35   N  N   . LEU A 1 61  ? 170.928 150.335 165.567 1.00 127.51 ? 61  LEU A N   1 
ATOM   36   C  CA  . LEU A 1 61  ? 171.315 150.282 166.974 1.00 127.51 ? 61  LEU A CA  1 
ATOM   37   C  C   . LEU A 1 61  ? 171.720 151.656 167.498 1.00 127.51 ? 61  LEU A C   1 
ATOM   38   O  O   . LEU A 1 61  ? 171.410 152.005 168.643 1.00 127.51 ? 61  LEU A O   1 
ATOM   39   C  CB  . LEU A 1 61  ? 172.454 149.281 167.158 1.00 127.51 ? 61  LEU A CB  1 
ATOM   40   C  CG  . LEU A 1 61  ? 172.852 148.921 168.589 1.00 127.51 ? 61  LEU A CG  1 
ATOM   41   C  CD1 . LEU A 1 61  ? 171.749 148.121 169.264 1.00 127.51 ? 61  LEU A CD1 1 
ATOM   42   C  CD2 . LEU A 1 61  ? 174.163 148.152 168.597 1.00 127.51 ? 61  LEU A CD2 1 
ATOM   43   N  N   . SER A 1 62  ? 172.418 152.446 166.679 1.00 125.85 ? 62  SER A N   1 
ATOM   44   C  CA  . SER A 1 62  ? 172.864 153.763 167.123 1.00 125.85 ? 62  SER A CA  1 
ATOM   45   C  C   . SER A 1 62  ? 171.705 154.749 167.203 1.00 125.85 ? 62  SER A C   1 
ATOM   46   O  O   . SER A 1 62  ? 171.674 155.608 168.092 1.00 125.85 ? 62  SER A O   1 
ATOM   47   C  CB  . SER A 1 62  ? 173.952 154.293 166.189 1.00 125.85 ? 62  SER A CB  1 
ATOM   48   O  OG  . SER A 1 62  ? 174.534 155.477 166.705 1.00 125.85 ? 62  SER A OG  1 
ATOM   49   N  N   . VAL A 1 63  ? 170.751 154.649 166.275 1.00 122.15 ? 63  VAL A N   1 
ATOM   50   C  CA  . VAL A 1 63  ? 169.612 155.563 166.270 1.00 122.15 ? 63  VAL A CA  1 
ATOM   51   C  C   . VAL A 1 63  ? 168.690 155.276 167.450 1.00 122.15 ? 63  VAL A C   1 
ATOM   52   O  O   . VAL A 1 63  ? 168.205 156.201 168.115 1.00 122.15 ? 63  VAL A O   1 
ATOM   53   C  CB  . VAL A 1 63  ? 168.879 155.476 164.917 1.00 122.15 ? 63  VAL A CB  1 
ATOM   54   C  CG1 . VAL A 1 63  ? 167.441 155.971 165.021 1.00 122.15 ? 63  VAL A CG1 1 
ATOM   55   C  CG2 . VAL A 1 63  ? 169.638 156.272 163.870 1.00 122.15 ? 63  VAL A CG2 1 
ATOM   56   N  N   . ALA A 1 64  ? 168.465 153.993 167.752 1.00 116.85 ? 64  ALA A N   1 
ATOM   57   C  CA  . ALA A 1 64  ? 167.612 153.613 168.873 1.00 116.85 ? 64  ALA A CA  1 
ATOM   58   C  C   . ALA A 1 64  ? 168.186 154.034 170.221 1.00 116.85 ? 64  ALA A C   1 
ATOM   59   O  O   . ALA A 1 64  ? 167.428 154.168 171.187 1.00 116.85 ? 64  ALA A O   1 
ATOM   60   C  CB  . ALA A 1 64  ? 167.371 152.103 168.860 1.00 116.85 ? 64  ALA A CB  1 
ATOM   61   N  N   . GLY A 1 65  ? 169.495 154.256 170.308 1.00 117.48 ? 65  GLY A N   1 
ATOM   62   C  CA  . GLY A 1 65  ? 170.090 154.762 171.526 1.00 117.48 ? 65  GLY A CA  1 
ATOM   63   C  C   . GLY A 1 65  ? 169.880 156.235 171.780 1.00 117.48 ? 65  GLY A C   1 
ATOM   64   O  O   . GLY A 1 65  ? 170.212 156.722 172.864 1.00 117.48 ? 65  GLY A O   1 
ATOM   65   N  N   . GLU A 1 66  ? 169.332 156.966 170.808 1.00 115.34 ? 66  GLU A N   1 
ATOM   66   C  CA  . GLU A 1 66  ? 169.043 158.382 170.964 1.00 115.34 ? 66  GLU A CA  1 
ATOM   67   C  C   . GLU A 1 66  ? 167.558 158.703 171.013 1.00 115.34 ? 66  GLU A C   1 
ATOM   68   O  O   . GLU A 1 66  ? 167.201 159.826 171.384 1.00 115.34 ? 66  GLU A O   1 
ATOM   69   C  CB  . GLU A 1 66  ? 169.680 159.191 169.823 1.00 115.34 ? 66  GLU A CB  1 
ATOM   70   C  CG  . GLU A 1 66  ? 171.174 158.970 169.666 1.00 115.34 ? 66  GLU A CG  1 
ATOM   71   C  CD  . GLU A 1 66  ? 171.899 160.209 169.180 1.00 115.34 ? 66  GLU A CD  1 
ATOM   72   O  OE1 . GLU A 1 66  ? 171.412 160.849 168.225 1.00 115.34 ? 66  GLU A OE1 1 
ATOM   73   O  OE2 . GLU A 1 66  ? 172.959 160.542 169.751 1.00 115.34 ? 66  GLU A OE2 1 
ATOM   74   N  N   . ILE A 1 67  ? 166.689 157.763 170.641 1.00 102.90 ? 67  ILE A N   1 
ATOM   75   C  CA  . ILE A 1 67  ? 165.251 158.000 170.715 1.00 102.90 ? 67  ILE A CA  1 
ATOM   76   C  C   . ILE A 1 67  ? 164.788 158.023 172.167 1.00 102.90 ? 67  ILE A C   1 
ATOM   77   O  O   . ILE A 1 67  ? 164.074 158.938 172.594 1.00 102.90 ? 67  ILE A O   1 
ATOM   78   C  CB  . ILE A 1 67  ? 164.498 156.936 169.897 1.00 102.90 ? 67  ILE A CB  1 
ATOM   79   C  CG1 . ILE A 1 67  ? 164.861 157.046 168.417 1.00 102.90 ? 67  ILE A CG1 1 
ATOM   80   C  CG2 . ILE A 1 67  ? 163.003 157.066 170.084 1.00 102.90 ? 67  ILE A CG2 1 
ATOM   81   C  CD1 . ILE A 1 67  ? 164.724 155.747 167.668 1.00 102.90 ? 67  ILE A CD1 1 
ATOM   82   N  N   . ILE A 1 68  ? 165.203 157.028 172.953 1.00 95.03  ? 68  ILE A N   1 
ATOM   83   C  CA  . ILE A 1 68  ? 164.728 156.923 174.328 1.00 95.03  ? 68  ILE A CA  1 
ATOM   84   C  C   . ILE A 1 68  ? 165.454 157.933 175.217 1.00 95.03  ? 68  ILE A C   1 
ATOM   85   O  O   . ILE A 1 68  ? 166.570 158.384 174.928 1.00 95.03  ? 68  ILE A O   1 
ATOM   86   C  CB  . ILE A 1 68  ? 164.897 155.480 174.839 1.00 95.03  ? 68  ILE A CB  1 
ATOM   87   C  CG1 . ILE A 1 68  ? 163.970 155.193 176.025 1.00 95.03  ? 68  ILE A CG1 1 
ATOM   88   C  CG2 . ILE A 1 68  ? 166.348 155.181 175.193 1.00 95.03  ? 68  ILE A CG2 1 
ATOM   89   C  CD1 . ILE A 1 68  ? 162.509 155.286 175.691 1.00 95.03  ? 68  ILE A CD1 1 
ATOM   90   N  N   . GLY A 1 69  ? 164.784 158.324 176.294 1.00 86.52  ? 69  GLY A N   1 
ATOM   91   C  CA  . GLY A 1 69  ? 165.357 159.252 177.251 1.00 86.52  ? 69  GLY A CA  1 
ATOM   92   C  C   . GLY A 1 69  ? 164.404 159.439 178.410 1.00 86.52  ? 69  GLY A C   1 
ATOM   93   O  O   . GLY A 1 69  ? 163.311 158.864 178.445 1.00 86.52  ? 69  GLY A O   1 
ATOM   94   N  N   . LEU A 1 70  ? 164.841 160.251 179.377 1.00 76.70  ? 70  LEU A N   1 
ATOM   95   C  CA  . LEU A 1 70  ? 163.990 160.530 180.530 1.00 76.70  ? 70  LEU A CA  1 
ATOM   96   C  C   . LEU A 1 70  ? 162.792 161.388 180.150 1.00 76.70  ? 70  LEU A C   1 
ATOM   97   O  O   . LEU A 1 70  ? 161.750 161.317 180.810 1.00 76.70  ? 70  LEU A O   1 
ATOM   98   C  CB  . LEU A 1 70  ? 164.792 161.213 181.636 1.00 76.70  ? 70  LEU A CB  1 
ATOM   99   C  CG  . LEU A 1 70  ? 165.424 160.309 182.692 1.00 76.70  ? 70  LEU A CG  1 
ATOM   100  C  CD1 . LEU A 1 70  ? 166.340 161.106 183.599 1.00 76.70  ? 70  LEU A CD1 1 
ATOM   101  C  CD2 . LEU A 1 70  ? 164.344 159.627 183.500 1.00 76.70  ? 70  LEU A CD2 1 
ATOM   102  N  N   . GLY A 1 71  ? 162.909 162.178 179.083 1.00 76.49  ? 71  GLY A N   1 
ATOM   103  C  CA  . GLY A 1 71  ? 161.810 163.009 178.625 1.00 76.49  ? 71  GLY A CA  1 
ATOM   104  C  C   . GLY A 1 71  ? 160.622 162.242 178.084 1.00 76.49  ? 71  GLY A C   1 
ATOM   105  O  O   . GLY A 1 71  ? 159.556 162.840 177.902 1.00 76.49  ? 71  GLY A O   1 
ATOM   106  N  N   . ASN A 1 72  ? 160.778 160.947 177.820 1.00 77.39  ? 72  ASN A N   1 
ATOM   107  C  CA  . ASN A 1 72  ? 159.681 160.100 177.375 1.00 77.39  ? 72  ASN A CA  1 
ATOM   108  C  C   . ASN A 1 72  ? 159.113 159.220 178.475 1.00 77.39  ? 72  ASN A C   1 
ATOM   109  O  O   . ASN A 1 72  ? 157.900 158.991 178.502 1.00 77.39  ? 72  ASN A O   1 
ATOM   110  C  CB  . ASN A 1 72  ? 160.135 159.210 176.215 1.00 77.39  ? 72  ASN A CB  1 
ATOM   111  C  CG  . ASN A 1 72  ? 161.000 159.950 175.225 1.00 77.39  ? 72  ASN A CG  1 
ATOM   112  O  OD1 . ASN A 1 72  ? 160.677 161.065 174.821 1.00 77.39  ? 72  ASN A OD1 1 
ATOM   113  N  ND2 . ASN A 1 72  ? 162.102 159.332 174.819 1.00 77.39  ? 72  ASN A ND2 1 
ATOM   114  N  N   . VAL A 1 73  ? 159.952 158.726 179.385 1.00 70.99  ? 73  VAL A N   1 
ATOM   115  C  CA  . VAL A 1 73  ? 159.493 157.795 180.409 1.00 70.99  ? 73  VAL A CA  1 
ATOM   116  C  C   . VAL A 1 73  ? 159.204 158.467 181.742 1.00 70.99  ? 73  VAL A C   1 
ATOM   117  O  O   . VAL A 1 73  ? 158.614 157.825 182.625 1.00 70.99  ? 73  VAL A O   1 
ATOM   118  C  CB  . VAL A 1 73  ? 160.506 156.648 180.617 1.00 70.99  ? 73  VAL A CB  1 
ATOM   119  C  CG1 . VAL A 1 73  ? 160.828 155.980 179.293 1.00 70.99  ? 73  VAL A CG1 1 
ATOM   120  C  CG2 . VAL A 1 73  ? 161.769 157.167 181.274 1.00 70.99  ? 73  VAL A CG2 1 
ATOM   121  N  N   . TRP A 1 74  ? 159.596 159.726 181.926 1.00 67.15  ? 74  TRP A N   1 
ATOM   122  C  CA  . TRP A 1 74  ? 159.359 160.406 183.193 1.00 67.15  ? 74  TRP A CA  1 
ATOM   123  C  C   . TRP A 1 74  ? 158.615 161.721 183.052 1.00 67.15  ? 74  TRP A C   1 
ATOM   124  O  O   . TRP A 1 74  ? 157.709 161.995 183.842 1.00 67.15  ? 74  TRP A O   1 
ATOM   125  C  CB  . TRP A 1 74  ? 160.691 160.655 183.912 1.00 67.15  ? 74  TRP A CB  1 
ATOM   126  C  CG  . TRP A 1 74  ? 160.608 161.694 184.985 1.00 67.15  ? 74  TRP A CG  1 
ATOM   127  C  CD1 . TRP A 1 74  ? 160.092 161.538 186.235 1.00 67.15  ? 74  TRP A CD1 1 
ATOM   128  C  CD2 . TRP A 1 74  ? 161.058 163.051 184.903 1.00 67.15  ? 74  TRP A CD2 1 
ATOM   129  N  NE1 . TRP A 1 74  ? 160.191 162.714 186.938 1.00 67.15  ? 74  TRP A NE1 1 
ATOM   130  C  CE2 . TRP A 1 74  ? 160.780 163.658 186.141 1.00 67.15  ? 74  TRP A CE2 1 
ATOM   131  C  CE3 . TRP A 1 74  ? 161.668 163.811 183.902 1.00 67.15  ? 74  TRP A CE3 1 
ATOM   132  C  CZ2 . TRP A 1 74  ? 161.091 164.987 186.404 1.00 67.15  ? 74  TRP A CZ2 1 
ATOM   133  C  CZ3 . TRP A 1 74  ? 161.972 165.131 184.165 1.00 67.15  ? 74  TRP A CZ3 1 
ATOM   134  C  CH2 . TRP A 1 74  ? 161.686 165.704 185.405 1.00 67.15  ? 74  TRP A CH2 1 
ATOM   135  N  N   . ARG A 1 75  ? 158.961 162.544 182.062 1.00 66.04  ? 75  ARG A N   1 
ATOM   136  C  CA  . ARG A 1 75  ? 158.388 163.880 181.973 1.00 66.04  ? 75  ARG A CA  1 
ATOM   137  C  C   . ARG A 1 75  ? 157.081 163.914 181.194 1.00 66.04  ? 75  ARG A C   1 
ATOM   138  O  O   . ARG A 1 75  ? 156.173 164.667 181.560 1.00 66.04  ? 75  ARG A O   1 
ATOM   139  C  CB  . ARG A 1 75  ? 159.391 164.846 181.339 1.00 66.04  ? 75  ARG A CB  1 
ATOM   140  C  CG  . ARG A 1 75  ? 159.035 166.304 181.546 1.00 66.04  ? 75  ARG A CG  1 
ATOM   141  C  CD  . ARG A 1 75  ? 160.111 167.233 181.029 1.00 66.04  ? 75  ARG A CD  1 
ATOM   142  N  NE  . ARG A 1 75  ? 159.535 168.409 180.390 1.00 66.04  ? 75  ARG A NE  1 
ATOM   143  C  CZ  . ARG A 1 75  ? 159.161 169.503 181.036 1.00 66.04  ? 75  ARG A CZ  1 
ATOM   144  N  NH1 . ARG A 1 75  ? 159.298 169.612 182.346 1.00 66.04  ? 75  ARG A NH1 1 
ATOM   145  N  NH2 . ARG A 1 75  ? 158.629 170.511 180.352 1.00 66.04  ? 75  ARG A NH2 1 
ATOM   146  N  N   . PHE A 1 76  ? 156.969 163.137 180.117 1.00 67.34  ? 76  PHE A N   1 
ATOM   147  C  CA  . PHE A 1 76  ? 155.734 163.154 179.334 1.00 67.34  ? 76  PHE A CA  1 
ATOM   148  C  C   . PHE A 1 76  ? 154.513 162.629 180.087 1.00 67.34  ? 76  PHE A C   1 
ATOM   149  O  O   . PHE A 1 76  ? 153.456 163.275 180.001 1.00 67.34  ? 76  PHE A O   1 
ATOM   150  C  CB  . PHE A 1 76  ? 155.928 162.415 178.005 1.00 67.34  ? 76  PHE A CB  1 
ATOM   151  C  CG  . PHE A 1 76  ? 154.652 162.219 177.241 1.00 67.34  ? 76  PHE A CG  1 
ATOM   152  C  CD1 . PHE A 1 76  ? 154.049 163.285 176.602 1.00 67.34  ? 76  PHE A CD1 1 
ATOM   153  C  CD2 . PHE A 1 76  ? 154.050 160.977 177.169 1.00 67.34  ? 76  PHE A CD2 1 
ATOM   154  C  CE1 . PHE A 1 76  ? 152.873 163.115 175.903 1.00 67.34  ? 76  PHE A CE1 1 
ATOM   155  C  CE2 . PHE A 1 76  ? 152.873 160.801 176.467 1.00 67.34  ? 76  PHE A CE2 1 
ATOM   156  C  CZ  . PHE A 1 76  ? 152.285 161.872 175.836 1.00 67.34  ? 76  PHE A CZ  1 
ATOM   157  N  N   . PRO A 1 77  ? 154.551 161.493 180.805 1.00 65.25  ? 77  PRO A N   1 
ATOM   158  C  CA  . PRO A 1 77  ? 153.351 161.110 181.568 1.00 65.25  ? 77  PRO A CA  1 
ATOM   159  C  C   . PRO A 1 77  ? 153.066 162.032 182.735 1.00 65.25  ? 77  PRO A C   1 
ATOM   160  O  O   . PRO A 1 77  ? 151.897 162.206 183.098 1.00 65.25  ? 77  PRO A O   1 
ATOM   161  C  CB  . PRO A 1 77  ? 153.672 159.687 182.033 1.00 65.25  ? 77  PRO A CB  1 
ATOM   162  C  CG  . PRO A 1 77  ? 154.685 159.215 181.066 1.00 65.25  ? 77  PRO A CG  1 
ATOM   163  C  CD  . PRO A 1 77  ? 155.542 160.403 180.863 1.00 65.25  ? 77  PRO A CD  1 
ATOM   164  N  N   . TYR A 1 78  ? 154.103 162.627 183.327 1.00 66.45  ? 78  TYR A N   1 
ATOM   165  C  CA  . TYR A 1 78  ? 153.915 163.705 184.294 1.00 66.45  ? 78  TYR A CA  1 
ATOM   166  C  C   . TYR A 1 78  ? 153.119 164.862 183.702 1.00 66.45  ? 78  TYR A C   1 
ATOM   167  O  O   . TYR A 1 78  ? 152.144 165.329 184.303 1.00 66.45  ? 78  TYR A O   1 
ATOM   168  C  CB  . TYR A 1 78  ? 155.280 164.176 184.796 1.00 66.45  ? 78  TYR A CB  1 
ATOM   169  C  CG  . TYR A 1 78  ? 155.311 165.595 185.305 1.00 66.45  ? 78  TYR A CG  1 
ATOM   170  C  CD1 . TYR A 1 78  ? 154.603 165.978 186.431 1.00 66.45  ? 78  TYR A CD1 1 
ATOM   171  C  CD2 . TYR A 1 78  ? 156.082 166.552 184.660 1.00 66.45  ? 78  TYR A CD2 1 
ATOM   172  C  CE1 . TYR A 1 78  ? 154.642 167.283 186.883 1.00 66.45  ? 78  TYR A CE1 1 
ATOM   173  C  CE2 . TYR A 1 78  ? 156.133 167.853 185.107 1.00 66.45  ? 78  TYR A CE2 1 
ATOM   174  C  CZ  . TYR A 1 78  ? 155.413 168.214 186.219 1.00 66.45  ? 78  TYR A CZ  1 
ATOM   175  O  OH  . TYR A 1 78  ? 155.460 169.512 186.669 1.00 66.45  ? 78  TYR A OH  1 
ATOM   176  N  N   . LEU A 1 79  ? 153.520 165.344 182.525 1.00 64.95  ? 79  LEU A N   1 
ATOM   177  C  CA  . LEU A 1 79  ? 152.827 166.486 181.944 1.00 64.95  ? 79  LEU A CA  1 
ATOM   178  C  C   . LEU A 1 79  ? 151.468 166.091 181.384 1.00 64.95  ? 79  LEU A C   1 
ATOM   179  O  O   . LEU A 1 79  ? 150.590 166.947 181.235 1.00 64.95  ? 79  LEU A O   1 
ATOM   180  C  CB  . LEU A 1 79  ? 153.689 167.129 180.862 1.00 64.95  ? 79  LEU A CB  1 
ATOM   181  C  CG  . LEU A 1 79  ? 154.838 167.974 181.407 1.00 64.95  ? 79  LEU A CG  1 
ATOM   182  C  CD1 . LEU A 1 79  ? 155.809 168.353 180.307 1.00 64.95  ? 79  LEU A CD1 1 
ATOM   183  C  CD2 . LEU A 1 79  ? 154.304 169.207 182.107 1.00 64.95  ? 79  LEU A CD2 1 
ATOM   184  N  N   . CYS A 1 80  ? 151.276 164.809 181.078 1.00 69.32  ? 80  CYS A N   1 
ATOM   185  C  CA  . CYS A 1 80  ? 149.989 164.332 180.595 1.00 69.32  ? 80  CYS A CA  1 
ATOM   186  C  C   . CYS A 1 80  ? 149.039 163.965 181.724 1.00 69.32  ? 80  CYS A C   1 
ATOM   187  O  O   . CYS A 1 80  ? 147.854 163.741 181.466 1.00 69.32  ? 80  CYS A O   1 
ATOM   188  C  CB  . CYS A 1 80  ? 150.189 163.122 179.682 1.00 69.32  ? 80  CYS A CB  1 
ATOM   189  S  SG  . CYS A 1 80  ? 148.866 162.862 178.490 1.00 69.32  ? 80  CYS A SG  1 
ATOM   190  N  N   . TYR A 1 81  ? 149.531 163.861 182.956 1.00 70.79  ? 81  TYR A N   1 
ATOM   191  C  CA  . TYR A 1 81  ? 148.660 163.670 184.108 1.00 70.79  ? 81  TYR A CA  1 
ATOM   192  C  C   . TYR A 1 81  ? 148.372 164.958 184.857 1.00 70.79  ? 81  TYR A C   1 
ATOM   193  O  O   . TYR A 1 81  ? 147.261 165.127 185.368 1.00 70.79  ? 81  TYR A O   1 
ATOM   194  C  CB  . TYR A 1 81  ? 149.274 162.662 185.079 1.00 70.79  ? 81  TYR A CB  1 
ATOM   195  C  CG  . TYR A 1 81  ? 148.355 162.258 186.205 1.00 70.79  ? 81  TYR A CG  1 
ATOM   196  C  CD1 . TYR A 1 81  ? 147.015 161.988 185.973 1.00 70.79  ? 81  TYR A CD1 1 
ATOM   197  C  CD2 . TYR A 1 81  ? 148.828 162.153 187.503 1.00 70.79  ? 81  TYR A CD2 1 
ATOM   198  C  CE1 . TYR A 1 81  ? 146.172 161.623 187.004 1.00 70.79  ? 81  TYR A CE1 1 
ATOM   199  C  CE2 . TYR A 1 81  ? 147.993 161.788 188.538 1.00 70.79  ? 81  TYR A CE2 1 
ATOM   200  C  CZ  . TYR A 1 81  ? 146.667 161.525 188.283 1.00 70.79  ? 81  TYR A CZ  1 
ATOM   201  O  OH  . TYR A 1 81  ? 145.833 161.162 189.312 1.00 70.79  ? 81  TYR A OH  1 
ATOM   202  N  N   . LYS A 1 82  ? 149.348 165.861 184.938 1.00 71.42  ? 82  LYS A N   1 
ATOM   203  C  CA  . LYS A 1 82  ? 149.143 167.120 185.644 1.00 71.42  ? 82  LYS A CA  1 
ATOM   204  C  C   . LYS A 1 82  ? 148.151 168.013 184.911 1.00 71.42  ? 82  LYS A C   1 
ATOM   205  O  O   . LYS A 1 82  ? 147.213 168.544 185.516 1.00 71.42  ? 82  LYS A O   1 
ATOM   206  C  CB  . LYS A 1 82  ? 150.482 167.830 185.813 1.00 71.42  ? 82  LYS A CB  1 
ATOM   207  C  CG  . LYS A 1 82  ? 150.387 169.212 186.402 1.00 71.42  ? 82  LYS A CG  1 
ATOM   208  C  CD  . LYS A 1 82  ? 151.772 169.786 186.580 1.00 71.42  ? 82  LYS A CD  1 
ATOM   209  C  CE  . LYS A 1 82  ? 151.730 171.156 187.212 1.00 71.42  ? 82  LYS A CE  1 
ATOM   210  N  NZ  . LYS A 1 82  ? 153.109 171.641 187.449 1.00 71.42  ? 82  LYS A NZ  1 
ATOM   211  N  N   . ASN A 1 83  ? 148.341 168.190 183.607 1.00 72.95  ? 83  ASN A N   1 
ATOM   212  C  CA  . ASN A 1 83  ? 147.501 169.086 182.813 1.00 72.95  ? 83  ASN A CA  1 
ATOM   213  C  C   . ASN A 1 83  ? 146.354 168.345 182.134 1.00 72.95  ? 83  ASN A C   1 
ATOM   214  O  O   . ASN A 1 83  ? 146.127 168.503 180.937 1.00 72.95  ? 83  ASN A O   1 
ATOM   215  C  CB  . ASN A 1 83  ? 148.364 169.800 181.784 1.00 72.95  ? 83  ASN A CB  1 
ATOM   216  C  CG  . ASN A 1 83  ? 149.320 170.780 182.413 1.00 72.95  ? 83  ASN A CG  1 
ATOM   217  O  OD1 . ASN A 1 83  ? 148.909 171.746 183.054 1.00 72.95  ? 83  ASN A OD1 1 
ATOM   218  N  ND2 . ASN A 1 83  ? 150.609 170.529 182.246 1.00 72.95  ? 83  ASN A ND2 1 
ATOM   219  N  N   . GLY A 1 84  ? 145.610 167.542 182.890 1.00 73.10  ? 84  GLY A N   1 
ATOM   220  C  CA  . GLY A 1 84  ? 144.507 166.789 182.322 1.00 73.10  ? 84  GLY A CA  1 
ATOM   221  C  C   . GLY A 1 84  ? 144.953 165.596 181.499 1.00 73.10  ? 84  GLY A C   1 
ATOM   222  O  O   . GLY A 1 84  ? 145.946 165.674 180.772 1.00 73.10  ? 84  GLY A O   1 
ATOM   223  N  N   . GLY A 1 85  ? 144.215 164.493 181.578 1.00 73.54  ? 85  GLY A N   1 
ATOM   224  C  CA  . GLY A 1 85  ? 144.636 163.265 180.931 1.00 73.54  ? 85  GLY A CA  1 
ATOM   225  C  C   . GLY A 1 85  ? 144.589 163.267 179.417 1.00 73.54  ? 85  GLY A C   1 
ATOM   226  O  O   . GLY A 1 85  ? 145.631 163.210 178.759 1.00 73.54  ? 85  GLY A O   1 
ATOM   227  N  N   . GLY A 1 86  ? 143.388 163.329 178.851 1.00 77.83  ? 86  GLY A N   1 
ATOM   228  C  CA  . GLY A 1 86  ? 143.237 163.255 177.411 1.00 77.83  ? 86  GLY A CA  1 
ATOM   229  C  C   . GLY A 1 86  ? 143.358 164.588 176.706 1.00 77.83  ? 86  GLY A C   1 
ATOM   230  O  O   . GLY A 1 86  ? 143.630 164.637 175.503 1.00 77.83  ? 86  GLY A O   1 
ATOM   231  N  N   . ALA A 1 87  ? 143.163 165.680 177.445 1.00 77.53  ? 87  ALA A N   1 
ATOM   232  C  CA  . ALA A 1 87  ? 143.221 167.007 176.847 1.00 77.53  ? 87  ALA A CA  1 
ATOM   233  C  C   . ALA A 1 87  ? 144.640 167.450 176.535 1.00 77.53  ? 87  ALA A C   1 
ATOM   234  O  O   . ALA A 1 87  ? 144.816 168.457 175.843 1.00 77.53  ? 87  ALA A O   1 
ATOM   235  C  CB  . ALA A 1 87  ? 142.554 168.028 177.768 1.00 77.53  ? 87  ALA A CB  1 
ATOM   236  N  N   . PHE A 1 88  ? 145.648 166.737 177.033 1.00 69.66  ? 88  PHE A N   1 
ATOM   237  C  CA  . PHE A 1 88  ? 147.032 167.088 176.750 1.00 69.66  ? 88  PHE A CA  1 
ATOM   238  C  C   . PHE A 1 88  ? 147.461 166.678 175.349 1.00 69.66  ? 88  PHE A C   1 
ATOM   239  O  O   . PHE A 1 88  ? 148.359 167.303 174.776 1.00 69.66  ? 88  PHE A O   1 
ATOM   240  C  CB  . PHE A 1 88  ? 147.947 166.443 177.790 1.00 69.66  ? 88  PHE A CB  1 
ATOM   241  C  CG  . PHE A 1 88  ? 149.392 166.795 177.630 1.00 69.66  ? 88  PHE A CG  1 
ATOM   242  C  CD1 . PHE A 1 88  ? 149.861 168.034 178.015 1.00 69.66  ? 88  PHE A CD1 1 
ATOM   243  C  CD2 . PHE A 1 88  ? 150.285 165.876 177.110 1.00 69.66  ? 88  PHE A CD2 1 
ATOM   244  C  CE1 . PHE A 1 88  ? 151.194 168.355 177.875 1.00 69.66  ? 88  PHE A CE1 1 
ATOM   245  C  CE2 . PHE A 1 88  ? 151.617 166.192 176.965 1.00 69.66  ? 88  PHE A CE2 1 
ATOM   246  C  CZ  . PHE A 1 88  ? 152.073 167.432 177.346 1.00 69.66  ? 88  PHE A CZ  1 
ATOM   247  N  N   . LEU A 1 89  ? 146.845 165.640 174.781 1.00 71.60  ? 89  LEU A N   1 
ATOM   248  C  CA  . LEU A 1 89  ? 147.319 165.117 173.504 1.00 71.60  ? 89  LEU A CA  1 
ATOM   249  C  C   . LEU A 1 89  ? 146.920 165.989 172.321 1.00 71.60  ? 89  LEU A C   1 
ATOM   250  O  O   . LEU A 1 89  ? 147.619 165.981 171.303 1.00 71.60  ? 89  LEU A O   1 
ATOM   251  C  CB  . LEU A 1 89  ? 146.808 163.696 173.289 1.00 71.60  ? 89  LEU A CB  1 
ATOM   252  C  CG  . LEU A 1 89  ? 147.245 162.687 174.346 1.00 71.60  ? 89  LEU A CG  1 
ATOM   253  C  CD1 . LEU A 1 89  ? 146.296 161.507 174.360 1.00 71.60  ? 89  LEU A CD1 1 
ATOM   254  C  CD2 . LEU A 1 89  ? 148.675 162.245 174.110 1.00 71.60  ? 89  LEU A CD2 1 
ATOM   255  N  N   . ILE A 1 90  ? 145.803 166.718 172.418 1.00 76.30  ? 90  ILE A N   1 
ATOM   256  C  CA  . ILE A 1 90  ? 145.370 167.564 171.301 1.00 76.30  ? 90  ILE A CA  1 
ATOM   257  C  C   . ILE A 1 90  ? 146.363 168.680 170.978 1.00 76.30  ? 90  ILE A C   1 
ATOM   258  O  O   . ILE A 1 90  ? 146.701 168.843 169.795 1.00 76.30  ? 90  ILE A O   1 
ATOM   259  C  CB  . ILE A 1 90  ? 143.936 168.072 171.543 1.00 76.30  ? 90  ILE A CB  1 
ATOM   260  C  CG1 . ILE A 1 90  ? 142.954 166.903 171.548 1.00 76.30  ? 90  ILE A CG1 1 
ATOM   261  C  CG2 . ILE A 1 90  ? 143.537 169.091 170.491 1.00 76.30  ? 90  ILE A CG2 1 
ATOM   262  C  CD1 . ILE A 1 90  ? 141.568 167.287 171.986 1.00 76.30  ? 90  ILE A CD1 1 
ATOM   263  N  N   . PRO A 1 91  ? 146.883 169.455 171.939 1.00 73.97  ? 91  PRO A N   1 
ATOM   264  C  CA  . PRO A 1 91  ? 147.992 170.350 171.592 1.00 73.97  ? 91  PRO A CA  1 
ATOM   265  C  C   . PRO A 1 91  ? 149.311 169.634 171.368 1.00 73.97  ? 91  PRO A C   1 
ATOM   266  O  O   . PRO A 1 91  ? 150.182 170.187 170.686 1.00 73.97  ? 91  PRO A O   1 
ATOM   267  C  CB  . PRO A 1 91  ? 148.071 171.281 172.806 1.00 73.97  ? 91  PRO A CB  1 
ATOM   268  C  CG  . PRO A 1 91  ? 147.646 170.445 173.902 1.00 73.97  ? 91  PRO A CG  1 
ATOM   269  C  CD  . PRO A 1 91  ? 146.490 169.683 173.344 1.00 73.97  ? 91  PRO A CD  1 
ATOM   270  N  N   . TYR A 1 92  ? 149.467 168.419 171.901 1.00 71.04  ? 92  TYR A N   1 
ATOM   271  C  CA  . TYR A 1 92  ? 150.698 167.664 171.701 1.00 71.04  ? 92  TYR A CA  1 
ATOM   272  C  C   . TYR A 1 92  ? 150.903 167.319 170.232 1.00 71.04  ? 92  TYR A C   1 
ATOM   273  O  O   . TYR A 1 92  ? 151.985 167.541 169.683 1.00 71.04  ? 92  TYR A O   1 
ATOM   274  C  CB  . TYR A 1 92  ? 150.680 166.394 172.547 1.00 71.04  ? 92  TYR A CB  1 
ATOM   275  C  CG  . TYR A 1 92  ? 152.004 165.670 172.600 1.00 71.04  ? 92  TYR A CG  1 
ATOM   276  C  CD1 . TYR A 1 92  ? 152.991 166.055 173.492 1.00 71.04  ? 92  TYR A CD1 1 
ATOM   277  C  CD2 . TYR A 1 92  ? 152.266 164.603 171.754 1.00 71.04  ? 92  TYR A CD2 1 
ATOM   278  C  CE1 . TYR A 1 92  ? 154.198 165.391 173.547 1.00 71.04  ? 92  TYR A CE1 1 
ATOM   279  C  CE2 . TYR A 1 92  ? 153.472 163.938 171.796 1.00 71.04  ? 92  TYR A CE2 1 
ATOM   280  C  CZ  . TYR A 1 92  ? 154.435 164.338 172.693 1.00 71.04  ? 92  TYR A CZ  1 
ATOM   281  O  OH  . TYR A 1 92  ? 155.640 163.677 172.740 1.00 71.04  ? 92  TYR A OH  1 
ATOM   282  N  N   . VAL A 1 93  ? 149.868 166.792 169.573 1.00 71.49  ? 93  VAL A N   1 
ATOM   283  C  CA  . VAL A 1 93  ? 150.005 166.447 168.161 1.00 71.49  ? 93  VAL A CA  1 
ATOM   284  C  C   . VAL A 1 93  ? 150.085 167.700 167.296 1.00 71.49  ? 93  VAL A C   1 
ATOM   285  O  O   . VAL A 1 93  ? 150.749 167.695 166.254 1.00 71.49  ? 93  VAL A O   1 
ATOM   286  C  CB  . VAL A 1 93  ? 148.865 165.514 167.709 1.00 71.49  ? 93  VAL A CB  1 
ATOM   287  C  CG1 . VAL A 1 93  ? 149.011 164.152 168.365 1.00 71.49  ? 93  VAL A CG1 1 
ATOM   288  C  CG2 . VAL A 1 93  ? 147.505 166.114 168.021 1.00 71.49  ? 93  VAL A CG2 1 
ATOM   289  N  N   . VAL A 1 94  ? 149.434 168.791 167.712 1.00 73.09  ? 94  VAL A N   1 
ATOM   290  C  CA  . VAL A 1 94  ? 149.506 170.041 166.956 1.00 73.09  ? 94  VAL A CA  1 
ATOM   291  C  C   . VAL A 1 94  ? 150.928 170.590 166.968 1.00 73.09  ? 94  VAL A C   1 
ATOM   292  O  O   . VAL A 1 94  ? 151.470 170.978 165.927 1.00 73.09  ? 94  VAL A O   1 
ATOM   293  C  CB  . VAL A 1 94  ? 148.494 171.061 167.509 1.00 73.09  ? 94  VAL A CB  1 
ATOM   294  C  CG1 . VAL A 1 94  ? 148.805 172.460 167.005 1.00 73.09  ? 94  VAL A CG1 1 
ATOM   295  C  CG2 . VAL A 1 94  ? 147.086 170.667 167.105 1.00 73.09  ? 94  VAL A CG2 1 
ATOM   296  N  N   . PHE A 1 95  ? 151.565 170.601 168.141 1.00 73.39  ? 95  PHE A N   1 
ATOM   297  C  CA  . PHE A 1 95  ? 152.953 171.044 168.203 1.00 73.39  ? 95  PHE A CA  1 
ATOM   298  C  C   . PHE A 1 95  ? 153.899 170.026 167.580 1.00 73.39  ? 95  PHE A C   1 
ATOM   299  O  O   . PHE A 1 95  ? 154.958 170.403 167.073 1.00 73.39  ? 95  PHE A O   1 
ATOM   300  C  CB  . PHE A 1 95  ? 153.353 171.331 169.645 1.00 73.39  ? 95  PHE A CB  1 
ATOM   301  C  CG  . PHE A 1 95  ? 153.150 172.758 170.050 1.00 73.39  ? 95  PHE A CG  1 
ATOM   302  C  CD1 . PHE A 1 95  ? 154.127 173.706 169.803 1.00 73.39  ? 95  PHE A CD1 1 
ATOM   303  C  CD2 . PHE A 1 95  ? 151.983 173.152 170.682 1.00 73.39  ? 95  PHE A CD2 1 
ATOM   304  C  CE1 . PHE A 1 95  ? 153.944 175.020 170.180 1.00 73.39  ? 95  PHE A CE1 1 
ATOM   305  C  CE2 . PHE A 1 95  ? 151.792 174.465 171.059 1.00 73.39  ? 95  PHE A CE2 1 
ATOM   306  C  CZ  . PHE A 1 95  ? 152.774 175.400 170.808 1.00 73.39  ? 95  PHE A CZ  1 
ATOM   307  N  N   . PHE A 1 96  ? 153.531 168.744 167.596 1.00 75.45  ? 96  PHE A N   1 
ATOM   308  C  CA  . PHE A 1 96  ? 154.323 167.721 166.925 1.00 75.45  ? 96  PHE A CA  1 
ATOM   309  C  C   . PHE A 1 96  ? 154.340 167.935 165.417 1.00 75.45  ? 96  PHE A C   1 
ATOM   310  O  O   . PHE A 1 96  ? 155.367 167.725 164.763 1.00 75.45  ? 96  PHE A O   1 
ATOM   311  C  CB  . PHE A 1 96  ? 153.766 166.344 167.284 1.00 75.45  ? 96  PHE A CB  1 
ATOM   312  C  CG  . PHE A 1 96  ? 154.216 165.242 166.378 1.00 75.45  ? 96  PHE A CG  1 
ATOM   313  C  CD1 . PHE A 1 96  ? 155.519 164.788 166.406 1.00 75.45  ? 96  PHE A CD1 1 
ATOM   314  C  CD2 . PHE A 1 96  ? 153.321 164.641 165.510 1.00 75.45  ? 96  PHE A CD2 1 
ATOM   315  C  CE1 . PHE A 1 96  ? 155.923 163.763 165.576 1.00 75.45  ? 96  PHE A CE1 1 
ATOM   316  C  CE2 . PHE A 1 96  ? 153.720 163.619 164.677 1.00 75.45  ? 96  PHE A CE2 1 
ATOM   317  C  CZ  . PHE A 1 96  ? 155.024 163.180 164.709 1.00 75.45  ? 96  PHE A CZ  1 
ATOM   318  N  N   . ILE A 1 97  ? 153.210 168.352 164.848 1.00 76.02  ? 97  ILE A N   1 
ATOM   319  C  CA  . ILE A 1 97  ? 153.150 168.621 163.415 1.00 76.02  ? 97  ILE A CA  1 
ATOM   320  C  C   . ILE A 1 97  ? 153.807 169.955 163.080 1.00 76.02  ? 97  ILE A C   1 
ATOM   321  O  O   . ILE A 1 97  ? 154.644 170.039 162.175 1.00 76.02  ? 97  ILE A O   1 
ATOM   322  C  CB  . ILE A 1 97  ? 151.693 168.568 162.920 1.00 76.02  ? 97  ILE A CB  1 
ATOM   323  C  CG1 . ILE A 1 97  ? 151.126 167.157 163.070 1.00 76.02  ? 97  ILE A CG1 1 
ATOM   324  C  CG2 . ILE A 1 97  ? 151.598 169.026 161.477 1.00 76.02  ? 97  ILE A CG2 1 
ATOM   325  C  CD1 . ILE A 1 97  ? 151.868 166.116 162.262 1.00 76.02  ? 97  ILE A CD1 1 
ATOM   326  N  N   . CYS A 1 98  ? 153.457 171.017 163.809 1.00 80.59  ? 98  CYS A N   1 
ATOM   327  C  CA  . CYS A 1 98  ? 153.799 172.368 163.384 1.00 80.59  ? 98  CYS A CA  1 
ATOM   328  C  C   . CYS A 1 98  ? 155.097 172.908 163.971 1.00 80.59  ? 98  CYS A C   1 
ATOM   329  O  O   . CYS A 1 98  ? 155.617 173.898 163.450 1.00 80.59  ? 98  CYS A O   1 
ATOM   330  C  CB  . CYS A 1 98  ? 152.664 173.335 163.739 1.00 80.59  ? 98  CYS A CB  1 
ATOM   331  S  SG  . CYS A 1 98  ? 151.094 172.970 162.927 1.00 80.59  ? 98  CYS A SG  1 
ATOM   332  N  N   . CYS A 1 99  ? 155.633 172.308 165.032 1.00 78.59  ? 99  CYS A N   1 
ATOM   333  C  CA  . CYS A 1 99  ? 156.826 172.839 165.678 1.00 78.59  ? 99  CYS A CA  1 
ATOM   334  C  C   . CYS A 1 99  ? 157.881 171.799 166.012 1.00 78.59  ? 99  CYS A C   1 
ATOM   335  O  O   . CYS A 1 99  ? 159.016 172.184 166.313 1.00 78.59  ? 99  CYS A O   1 
ATOM   336  C  CB  . CYS A 1 99  ? 156.452 173.581 166.968 1.00 78.59  ? 99  CYS A CB  1 
ATOM   337  S  SG  . CYS A 1 99  ? 155.437 175.044 166.711 1.00 78.59  ? 99  CYS A SG  1 
ATOM   338  N  N   . GLY A 1 100 ? 157.560 170.512 165.989 1.00 80.29  ? 100 GLY A N   1 
ATOM   339  C  CA  . GLY A 1 100 ? 158.580 169.506 166.193 1.00 80.29  ? 100 GLY A CA  1 
ATOM   340  C  C   . GLY A 1 100 ? 159.375 169.285 164.926 1.00 80.29  ? 100 GLY A C   1 
ATOM   341  O  O   . GLY A 1 100 ? 160.602 169.442 164.913 1.00 80.29  ? 100 GLY A O   1 
ATOM   342  N  N   . ILE A 1 101 ? 158.660 168.931 163.851 1.00 81.84  ? 101 ILE A N   1 
ATOM   343  C  CA  . ILE A 1 101 ? 159.307 168.719 162.553 1.00 81.84  ? 101 ILE A CA  1 
ATOM   344  C  C   . ILE A 1 101 ? 160.044 169.953 162.034 1.00 81.84  ? 101 ILE A C   1 
ATOM   345  O  O   . ILE A 1 101 ? 161.232 169.829 161.691 1.00 81.84  ? 101 ILE A O   1 
ATOM   346  C  CB  . ILE A 1 101 ? 158.286 168.175 161.537 1.00 81.84  ? 101 ILE A CB  1 
ATOM   347  C  CG1 . ILE A 1 101 ? 157.506 166.997 162.122 1.00 81.84  ? 101 ILE A CG1 1 
ATOM   348  C  CG2 . ILE A 1 101 ? 158.978 167.796 160.236 1.00 81.84  ? 101 ILE A CG2 1 
ATOM   349  C  CD1 . ILE A 1 101 ? 158.295 165.720 162.186 1.00 81.84  ? 101 ILE A CD1 1 
ATOM   350  N  N   . PRO A 1 102 ? 159.433 171.154 161.953 1.00 79.41  ? 102 PRO A N   1 
ATOM   351  C  CA  . PRO A 1 102 ? 160.169 172.265 161.323 1.00 79.41  ? 102 PRO A CA  1 
ATOM   352  C  C   . PRO A 1 102 ? 161.365 172.740 162.123 1.00 79.41  ? 102 PRO A C   1 
ATOM   353  O  O   . PRO A 1 102 ? 162.440 172.932 161.546 1.00 79.41  ? 102 PRO A O   1 
ATOM   354  C  CB  . PRO A 1 102 ? 159.103 173.363 161.195 1.00 79.41  ? 102 PRO A CB  1 
ATOM   355  C  CG  . PRO A 1 102 ? 157.815 172.651 161.296 1.00 79.41  ? 102 PRO A CG  1 
ATOM   356  C  CD  . PRO A 1 102 ? 158.077 171.613 162.313 1.00 79.41  ? 102 PRO A CD  1 
ATOM   357  N  N   . VAL A 1 103 ? 161.221 172.923 163.435 1.00 81.11  ? 103 VAL A N   1 
ATOM   358  C  CA  . VAL A 1 103 ? 162.350 173.394 164.229 1.00 81.11  ? 103 VAL A CA  1 
ATOM   359  C  C   . VAL A 1 103 ? 163.421 172.310 164.364 1.00 81.11  ? 103 VAL A C   1 
ATOM   360  O  O   . VAL A 1 103 ? 164.620 172.622 164.382 1.00 81.11  ? 103 VAL A O   1 
ATOM   361  C  CB  . VAL A 1 103 ? 161.863 173.901 165.596 1.00 81.11  ? 103 VAL A CB  1 
ATOM   362  C  CG1 . VAL A 1 103 ? 162.989 174.590 166.340 1.00 81.11  ? 103 VAL A CG1 1 
ATOM   363  C  CG2 . VAL A 1 103 ? 160.704 174.861 165.411 1.00 81.11  ? 103 VAL A CG2 1 
ATOM   364  N  N   . PHE A 1 104 ? 163.022 171.035 164.443 1.00 86.14  ? 104 PHE A N   1 
ATOM   365  C  CA  . PHE A 1 104 ? 163.997 169.946 164.475 1.00 86.14  ? 104 PHE A CA  1 
ATOM   366  C  C   . PHE A 1 104 ? 164.811 169.904 163.187 1.00 86.14  ? 104 PHE A C   1 
ATOM   367  O  O   . PHE A 1 104 ? 166.046 169.800 163.221 1.00 86.14  ? 104 PHE A O   1 
ATOM   368  C  CB  . PHE A 1 104 ? 163.275 168.616 164.708 1.00 86.14  ? 104 PHE A CB  1 
ATOM   369  C  CG  . PHE A 1 104 ? 164.185 167.473 165.078 1.00 86.14  ? 104 PHE A CG  1 
ATOM   370  C  CD1 . PHE A 1 104 ? 165.453 167.699 165.588 1.00 86.14  ? 104 PHE A CD1 1 
ATOM   371  C  CD2 . PHE A 1 104 ? 163.757 166.165 164.928 1.00 86.14  ? 104 PHE A CD2 1 
ATOM   372  C  CE1 . PHE A 1 104 ? 166.280 166.645 165.925 1.00 86.14  ? 104 PHE A CE1 1 
ATOM   373  C  CE2 . PHE A 1 104 ? 164.579 165.108 165.265 1.00 86.14  ? 104 PHE A CE2 1 
ATOM   374  C  CZ  . PHE A 1 104 ? 165.842 165.350 165.766 1.00 86.14  ? 104 PHE A CZ  1 
ATOM   375  N  N   . PHE A 1 105 ? 164.133 170.009 162.040 1.00 87.64  ? 105 PHE A N   1 
ATOM   376  C  CA  . PHE A 1 105 ? 164.827 170.025 160.758 1.00 87.64  ? 105 PHE A CA  1 
ATOM   377  C  C   . PHE A 1 105 ? 165.709 171.259 160.625 1.00 87.64  ? 105 PHE A C   1 
ATOM   378  O  O   . PHE A 1 105 ? 166.822 171.177 160.093 1.00 87.64  ? 105 PHE A O   1 
ATOM   379  C  CB  . PHE A 1 105 ? 163.807 169.956 159.624 1.00 87.64  ? 105 PHE A CB  1 
ATOM   380  C  CG  . PHE A 1 105 ? 164.414 170.016 158.257 1.00 87.64  ? 105 PHE A CG  1 
ATOM   381  C  CD1 . PHE A 1 105 ? 165.463 169.183 157.911 1.00 87.64  ? 105 PHE A CD1 1 
ATOM   382  C  CD2 . PHE A 1 105 ? 163.927 170.900 157.312 1.00 87.64  ? 105 PHE A CD2 1 
ATOM   383  C  CE1 . PHE A 1 105 ? 166.020 169.237 156.649 1.00 87.64  ? 105 PHE A CE1 1 
ATOM   384  C  CE2 . PHE A 1 105 ? 164.479 170.957 156.050 1.00 87.64  ? 105 PHE A CE2 1 
ATOM   385  C  CZ  . PHE A 1 105 ? 165.527 170.124 155.719 1.00 87.64  ? 105 PHE A CZ  1 
ATOM   386  N  N   . LEU A 1 106 ? 165.237 172.402 161.133 1.00 82.95  ? 106 LEU A N   1 
ATOM   387  C  CA  . LEU A 1 106 ? 166.016 173.636 161.107 1.00 82.95  ? 106 LEU A CA  1 
ATOM   388  C  C   . LEU A 1 106 ? 167.315 173.487 161.886 1.00 82.95  ? 106 LEU A C   1 
ATOM   389  O  O   . LEU A 1 106 ? 168.393 173.826 161.385 1.00 82.95  ? 106 LEU A O   1 
ATOM   390  C  CB  . LEU A 1 106 ? 165.179 174.778 161.685 1.00 82.95  ? 106 LEU A CB  1 
ATOM   391  C  CG  . LEU A 1 106 ? 165.630 176.231 161.543 1.00 82.95  ? 106 LEU A CG  1 
ATOM   392  C  CD1 . LEU A 1 106 ? 164.408 177.100 161.397 1.00 82.95  ? 106 LEU A CD1 1 
ATOM   393  C  CD2 . LEU A 1 106 ? 166.447 176.695 162.735 1.00 82.95  ? 106 LEU A CD2 1 
ATOM   394  N  N   . GLU A 1 107 ? 167.229 172.984 163.120 1.00 90.61  ? 107 GLU A N   1 
ATOM   395  C  CA  . GLU A 1 107 ? 168.425 172.879 163.950 1.00 90.61  ? 107 GLU A CA  1 
ATOM   396  C  C   . GLU A 1 107 ? 169.386 171.823 163.421 1.00 90.61  ? 107 GLU A C   1 
ATOM   397  O  O   . GLU A 1 107 ? 170.605 172.032 163.439 1.00 90.61  ? 107 GLU A O   1 
ATOM   398  C  CB  . GLU A 1 107 ? 168.048 172.594 165.401 1.00 90.61  ? 107 GLU A CB  1 
ATOM   399  C  CG  . GLU A 1 107 ? 167.531 173.818 166.132 1.00 90.61  ? 107 GLU A CG  1 
ATOM   400  C  CD  . GLU A 1 107 ? 167.377 173.591 167.619 1.00 90.61  ? 107 GLU A CD  1 
ATOM   401  O  OE1 . GLU A 1 107 ? 167.529 172.437 168.066 1.00 90.61  ? 107 GLU A OE1 1 
ATOM   402  O  OE2 . GLU A 1 107 ? 167.119 174.571 168.345 1.00 90.61  ? 107 GLU A OE2 1 
ATOM   403  N  N   . THR A 1 108 ? 168.863 170.693 162.928 1.00 91.45  ? 108 THR A N   1 
ATOM   404  C  CA  . THR A 1 108 ? 169.738 169.677 162.349 1.00 91.45  ? 108 THR A CA  1 
ATOM   405  C  C   . THR A 1 108 ? 170.448 170.197 161.104 1.00 91.45  ? 108 THR A C   1 
ATOM   406  O  O   . THR A 1 108 ? 171.664 170.003 160.945 1.00 91.45  ? 108 THR A O   1 
ATOM   407  C  CB  . THR A 1 108 ? 168.935 168.420 162.019 1.00 91.45  ? 108 THR A CB  1 
ATOM   408  O  OG1 . THR A 1 108 ? 168.086 168.093 163.124 1.00 91.45  ? 108 THR A OG1 1 
ATOM   409  C  CG2 . THR A 1 108 ? 169.865 167.255 161.745 1.00 91.45  ? 108 THR A CG2 1 
ATOM   410  N  N   . ALA A 1 109 ? 169.711 170.883 160.222 1.00 92.94  ? 109 ALA A N   1 
ATOM   411  C  CA  . ALA A 1 109 ? 170.305 171.423 159.006 1.00 92.94  ? 109 ALA A CA  1 
ATOM   412  C  C   . ALA A 1 109 ? 171.334 172.500 159.316 1.00 92.94  ? 109 ALA A C   1 
ATOM   413  O  O   . ALA A 1 109 ? 172.394 172.542 158.687 1.00 92.94  ? 109 ALA A O   1 
ATOM   414  C  CB  . ALA A 1 109 ? 169.214 171.972 158.090 1.00 92.94  ? 109 ALA A CB  1 
ATOM   415  N  N   . LEU A 1 110 ? 171.048 173.372 160.288 1.00 93.57  ? 110 LEU A N   1 
ATOM   416  C  CA  . LEU A 1 110 ? 172.005 174.414 160.650 1.00 93.57  ? 110 LEU A CA  1 
ATOM   417  C  C   . LEU A 1 110 ? 173.260 173.825 161.282 1.00 93.57  ? 110 LEU A C   1 
ATOM   418  O  O   . LEU A 1 110 ? 174.377 174.278 160.994 1.00 93.57  ? 110 LEU A O   1 
ATOM   419  C  CB  . LEU A 1 110 ? 171.350 175.417 161.595 1.00 93.57  ? 110 LEU A CB  1 
ATOM   420  C  CG  . LEU A 1 110 ? 171.920 176.834 161.550 1.00 93.57  ? 110 LEU A CG  1 
ATOM   421  C  CD1 . LEU A 1 110 ? 171.670 177.475 160.199 1.00 93.57  ? 110 LEU A CD1 1 
ATOM   422  C  CD2 . LEU A 1 110 ? 171.320 177.672 162.655 1.00 93.57  ? 110 LEU A CD2 1 
ATOM   423  N  N   . GLY A 1 111 ? 173.097 172.815 162.140 1.00 99.43  ? 111 GLY A N   1 
ATOM   424  C  CA  . GLY A 1 111 ? 174.251 172.189 162.761 1.00 99.43  ? 111 GLY A CA  1 
ATOM   425  C  C   . GLY A 1 111 ? 175.134 171.466 161.767 1.00 99.43  ? 111 GLY A C   1 
ATOM   426  O  O   . GLY A 1 111 ? 176.363 171.502 161.876 1.00 99.43  ? 111 GLY A O   1 
ATOM   427  N  N   . GLN A 1 112 ? 174.528 170.802 160.782 1.00 102.98 ? 112 GLN A N   1 
ATOM   428  C  CA  . GLN A 1 112 ? 175.341 170.152 159.762 1.00 102.98 ? 112 GLN A CA  1 
ATOM   429  C  C   . GLN A 1 112 ? 175.931 171.160 158.778 1.00 102.98 ? 112 GLN A C   1 
ATOM   430  O  O   . GLN A 1 112 ? 177.042 170.951 158.276 1.00 102.98 ? 112 GLN A O   1 
ATOM   431  C  CB  . GLN A 1 112 ? 174.510 169.079 159.054 1.00 102.98 ? 112 GLN A CB  1 
ATOM   432  C  CG  . GLN A 1 112 ? 175.174 168.429 157.859 1.00 102.98 ? 112 GLN A CG  1 
ATOM   433  C  CD  . GLN A 1 112 ? 174.358 167.290 157.298 1.00 102.98 ? 112 GLN A CD  1 
ATOM   434  O  OE1 . GLN A 1 112 ? 173.467 166.768 157.963 1.00 102.98 ? 112 GLN A OE1 1 
ATOM   435  N  NE2 . GLN A 1 112 ? 174.643 166.911 156.062 1.00 102.98 ? 112 GLN A NE2 1 
ATOM   436  N  N   . PHE A 1 113 ? 175.229 172.269 158.525 1.00 101.28 ? 113 PHE A N   1 
ATOM   437  C  CA  . PHE A 1 113 ? 175.734 173.294 157.619 1.00 101.28 ? 113 PHE A CA  1 
ATOM   438  C  C   . PHE A 1 113 ? 176.965 173.985 158.188 1.00 101.28 ? 113 PHE A C   1 
ATOM   439  O  O   . PHE A 1 113 ? 177.997 174.087 157.517 1.00 101.28 ? 113 PHE A O   1 
ATOM   440  C  CB  . PHE A 1 113 ? 174.633 174.319 157.339 1.00 101.28 ? 113 PHE A CB  1 
ATOM   441  C  CG  . PHE A 1 113 ? 175.011 175.364 156.331 1.00 101.28 ? 113 PHE A CG  1 
ATOM   442  C  CD1 . PHE A 1 113 ? 175.774 175.039 155.221 1.00 101.28 ? 113 PHE A CD1 1 
ATOM   443  C  CD2 . PHE A 1 113 ? 174.594 176.675 156.491 1.00 101.28 ? 113 PHE A CD2 1 
ATOM   444  C  CE1 . PHE A 1 113 ? 176.120 176.004 154.294 1.00 101.28 ? 113 PHE A CE1 1 
ATOM   445  C  CE2 . PHE A 1 113 ? 174.934 177.642 155.567 1.00 101.28 ? 113 PHE A CE2 1 
ATOM   446  C  CZ  . PHE A 1 113 ? 175.698 177.307 154.468 1.00 101.28 ? 113 PHE A CZ  1 
ATOM   447  N  N   . THR A 1 114 ? 176.877 174.466 159.428 1.00 106.63 ? 114 THR A N   1 
ATOM   448  C  CA  . THR A 1 114 ? 177.983 175.245 159.968 1.00 106.63 ? 114 THR A CA  1 
ATOM   449  C  C   . THR A 1 114 ? 179.123 174.350 160.445 1.00 106.63 ? 114 THR A C   1 
ATOM   450  O  O   . THR A 1 114 ? 180.293 174.736 160.333 1.00 106.63 ? 114 THR A O   1 
ATOM   451  C  CB  . THR A 1 114 ? 177.478 176.145 161.093 1.00 106.63 ? 114 THR A CB  1 
ATOM   452  O  OG1 . THR A 1 114 ? 176.313 176.845 160.642 1.00 106.63 ? 114 THR A OG1 1 
ATOM   453  C  CG2 . THR A 1 114 ? 178.519 177.184 161.435 1.00 106.63 ? 114 THR A CG2 1 
ATOM   454  N  N   . SER A 1 115 ? 178.793 173.158 160.958 1.00 109.27 ? 115 SER A N   1 
ATOM   455  C  CA  . SER A 1 115 ? 179.760 172.113 161.323 1.00 109.27 ? 115 SER A CA  1 
ATOM   456  C  C   . SER A 1 115 ? 180.741 172.586 162.397 1.00 109.27 ? 115 SER A C   1 
ATOM   457  O  O   . SER A 1 115 ? 181.958 172.448 162.263 1.00 109.27 ? 115 SER A O   1 
ATOM   458  C  CB  . SER A 1 115 ? 180.508 171.591 160.091 1.00 109.27 ? 115 SER A CB  1 
ATOM   459  O  OG  . SER A 1 115 ? 179.734 170.635 159.387 1.00 109.27 ? 115 SER A OG  1 
ATOM   460  N  N   . GLU A 1 116 ? 180.196 173.139 163.475 1.00 111.71 ? 116 GLU A N   1 
ATOM   461  C  CA  . GLU A 1 116 ? 180.995 173.565 164.620 1.00 111.71 ? 116 GLU A CA  1 
ATOM   462  C  C   . GLU A 1 116 ? 180.082 173.606 165.845 1.00 111.71 ? 116 GLU A C   1 
ATOM   463  O  O   . GLU A 1 116 ? 178.986 173.033 165.829 1.00 111.71 ? 116 GLU A O   1 
ATOM   464  C  CB  . GLU A 1 116 ? 181.679 174.913 164.336 1.00 111.71 ? 116 GLU A CB  1 
ATOM   465  C  CG  . GLU A 1 116 ? 180.722 176.057 164.098 1.00 111.71 ? 116 GLU A CG  1 
ATOM   466  C  CD  . GLU A 1 116 ? 181.431 177.330 163.691 1.00 111.71 ? 116 GLU A CD  1 
ATOM   467  O  OE1 . GLU A 1 116 ? 182.635 177.267 163.367 1.00 111.71 ? 116 GLU A OE1 1 
ATOM   468  O  OE2 . GLU A 1 116 ? 180.786 178.398 163.711 1.00 111.71 ? 116 GLU A OE2 1 
ATOM   469  N  N   . GLY A 1 117 ? 180.539 174.271 166.906 1.00 114.83 ? 117 GLY A N   1 
ATOM   470  C  CA  . GLY A 1 117 ? 179.766 174.375 168.126 1.00 114.83 ? 117 GLY A CA  1 
ATOM   471  C  C   . GLY A 1 117 ? 178.477 175.159 167.946 1.00 114.83 ? 117 GLY A C   1 
ATOM   472  O  O   . GLY A 1 117 ? 178.271 175.887 166.974 1.00 114.83 ? 117 GLY A O   1 
ATOM   473  N  N   . GLY A 1 118 ? 177.589 175.002 168.926 1.00 111.24 ? 118 GLY A N   1 
ATOM   474  C  CA  . GLY A 1 118 ? 176.231 175.497 168.807 1.00 111.24 ? 118 GLY A CA  1 
ATOM   475  C  C   . GLY A 1 118 ? 176.027 176.965 169.103 1.00 111.24 ? 118 GLY A C   1 
ATOM   476  O  O   . GLY A 1 118 ? 174.886 177.432 169.042 1.00 111.24 ? 118 GLY A O   1 
ATOM   477  N  N   . ILE A 1 119 ? 177.084 177.707 169.430 1.00 107.80 ? 119 ILE A N   1 
ATOM   478  C  CA  . ILE A 1 119 ? 176.927 179.118 169.768 1.00 107.80 ? 119 ILE A CA  1 
ATOM   479  C  C   . ILE A 1 119 ? 177.737 179.992 168.817 1.00 107.80 ? 119 ILE A C   1 
ATOM   480  O  O   . ILE A 1 119 ? 177.407 181.163 168.605 1.00 107.80 ? 119 ILE A O   1 
ATOM   481  C  CB  . ILE A 1 119 ? 177.306 179.379 171.237 1.00 107.80 ? 119 ILE A CB  1 
ATOM   482  C  CG1 . ILE A 1 119 ? 178.763 179.008 171.509 1.00 107.80 ? 119 ILE A CG1 1 
ATOM   483  C  CG2 . ILE A 1 119 ? 176.405 178.587 172.151 1.00 107.80 ? 119 ILE A CG2 1 
ATOM   484  C  CD1 . ILE A 1 119 ? 179.240 179.428 172.879 1.00 107.80 ? 119 ILE A CD1 1 
ATOM   485  N  N   . THR A 1 120 ? 178.803 179.435 168.243 1.00 108.09 ? 120 THR A N   1 
ATOM   486  C  CA  . THR A 1 120 ? 179.489 180.105 167.146 1.00 108.09 ? 120 THR A CA  1 
ATOM   487  C  C   . THR A 1 120 ? 178.832 179.814 165.805 1.00 108.09 ? 120 THR A C   1 
ATOM   488  O  O   . THR A 1 120 ? 179.116 180.510 164.820 1.00 108.09 ? 120 THR A O   1 
ATOM   489  C  CB  . THR A 1 120 ? 180.964 179.698 167.119 1.00 108.09 ? 120 THR A CB  1 
ATOM   490  O  OG1 . THR A 1 120 ? 181.606 180.278 165.976 1.00 108.09 ? 120 THR A OG1 1 
ATOM   491  C  CG2 . THR A 1 120 ? 181.104 178.188 167.088 1.00 108.09 ? 120 THR A CG2 1 
ATOM   492  N  N   . CYS A 1 121 ? 177.958 178.805 165.757 1.00 108.44 ? 121 CYS A N   1 
ATOM   493  C  CA  . CYS A 1 121 ? 177.140 178.571 164.573 1.00 108.44 ? 121 CYS A CA  1 
ATOM   494  C  C   . CYS A 1 121 ? 176.246 179.767 164.288 1.00 108.44 ? 121 CYS A C   1 
ATOM   495  O  O   . CYS A 1 121 ? 176.161 180.238 163.148 1.00 108.44 ? 121 CYS A O   1 
ATOM   496  C  CB  . CYS A 1 121 ? 176.302 177.308 164.760 1.00 108.44 ? 121 CYS A CB  1 
ATOM   497  S  SG  . CYS A 1 121 ? 174.954 177.136 163.580 1.00 108.44 ? 121 CYS A SG  1 
ATOM   498  N  N   . TRP A 1 122 ? 175.591 180.291 165.323 1.00 99.26  ? 122 TRP A N   1 
ATOM   499  C  CA  . TRP A 1 122 ? 174.812 181.508 165.160 1.00 99.26  ? 122 TRP A CA  1 
ATOM   500  C  C   . TRP A 1 122 ? 175.691 182.723 164.912 1.00 99.26  ? 122 TRP A C   1 
ATOM   501  O  O   . TRP A 1 122 ? 175.214 183.705 164.337 1.00 99.26  ? 122 TRP A O   1 
ATOM   502  C  CB  . TRP A 1 122 ? 173.931 181.728 166.386 1.00 99.26  ? 122 TRP A CB  1 
ATOM   503  C  CG  . TRP A 1 122 ? 172.852 180.715 166.478 1.00 99.26  ? 122 TRP A CG  1 
ATOM   504  C  CD1 . TRP A 1 122 ? 172.796 179.650 167.325 1.00 99.26  ? 122 TRP A CD1 1 
ATOM   505  C  CD2 . TRP A 1 122 ? 171.669 180.658 165.680 1.00 99.26  ? 122 TRP A CD2 1 
ATOM   506  N  NE1 . TRP A 1 122 ? 171.646 178.933 167.107 1.00 99.26  ? 122 TRP A NE1 1 
ATOM   507  C  CE2 . TRP A 1 122 ? 170.936 179.534 166.101 1.00 99.26  ? 122 TRP A CE2 1 
ATOM   508  C  CE3 . TRP A 1 122 ? 171.155 181.452 164.653 1.00 99.26  ? 122 TRP A CE3 1 
ATOM   509  C  CZ2 . TRP A 1 122 ? 169.721 179.184 165.532 1.00 99.26  ? 122 TRP A CZ2 1 
ATOM   510  C  CZ3 . TRP A 1 122 ? 169.947 181.103 164.088 1.00 99.26  ? 122 TRP A CZ3 1 
ATOM   511  C  CH2 . TRP A 1 122 ? 169.243 179.980 164.528 1.00 99.26  ? 122 TRP A CH2 1 
ATOM   512  N  N   . ARG A 1 123 ? 176.960 182.679 165.326 1.00 105.72 ? 123 ARG A N   1 
ATOM   513  C  CA  . ARG A 1 123 ? 177.876 183.764 164.992 1.00 105.72 ? 123 ARG A CA  1 
ATOM   514  C  C   . ARG A 1 123 ? 178.167 183.795 163.497 1.00 105.72 ? 123 ARG A C   1 
ATOM   515  O  O   . ARG A 1 123 ? 178.151 184.867 162.880 1.00 105.72 ? 123 ARG A O   1 
ATOM   516  C  CB  . ARG A 1 123 ? 179.172 183.630 165.790 1.00 105.72 ? 123 ARG A CB  1 
ATOM   517  C  CG  . ARG A 1 123 ? 180.278 184.570 165.336 1.00 105.72 ? 123 ARG A CG  1 
ATOM   518  C  CD  . ARG A 1 123 ? 180.990 185.208 166.517 1.00 105.72 ? 123 ARG A CD  1 
ATOM   519  N  NE  . ARG A 1 123 ? 181.129 184.286 167.637 1.00 105.72 ? 123 ARG A NE  1 
ATOM   520  C  CZ  . ARG A 1 123 ? 182.109 183.402 167.760 1.00 105.72 ? 123 ARG A CZ  1 
ATOM   521  N  NH1 . ARG A 1 123 ? 183.062 183.295 166.847 1.00 105.72 ? 123 ARG A NH1 1 
ATOM   522  N  NH2 . ARG A 1 123 ? 182.135 182.606 168.825 1.00 105.72 ? 123 ARG A NH2 1 
ATOM   523  N  N   . LYS A 1 124 ? 178.416 182.634 162.890 1.00 106.49 ? 124 LYS A N   1 
ATOM   524  C  CA  . LYS A 1 124 ? 178.716 182.613 161.464 1.00 106.49 ? 124 LYS A CA  1 
ATOM   525  C  C   . LYS A 1 124 ? 177.480 182.538 160.577 1.00 106.49 ? 124 LYS A C   1 
ATOM   526  O  O   . LYS A 1 124 ? 177.613 182.667 159.356 1.00 106.49 ? 124 LYS A O   1 
ATOM   527  C  CB  . LYS A 1 124 ? 179.660 181.455 161.120 1.00 106.49 ? 124 LYS A CB  1 
ATOM   528  C  CG  . LYS A 1 124 ? 180.876 181.354 162.029 1.00 106.49 ? 124 LYS A CG  1 
ATOM   529  C  CD  . LYS A 1 124 ? 181.984 180.469 161.448 1.00 106.49 ? 124 LYS A CD  1 
ATOM   530  C  CE  . LYS A 1 124 ? 181.453 179.320 160.601 1.00 106.49 ? 124 LYS A CE  1 
ATOM   531  N  NZ  . LYS A 1 124 ? 182.429 178.199 160.522 1.00 106.49 ? 124 LYS A NZ  1 
ATOM   532  N  N   . VAL A 1 125 ? 176.290 182.343 161.139 1.00 101.51 ? 125 VAL A N   1 
ATOM   533  C  CA  . VAL A 1 125 ? 175.067 182.398 160.338 1.00 101.51 ? 125 VAL A CA  1 
ATOM   534  C  C   . VAL A 1 125 ? 174.448 183.788 160.366 1.00 101.51 ? 125 VAL A C   1 
ATOM   535  O  O   . VAL A 1 125 ? 174.216 184.395 159.318 1.00 101.51 ? 125 VAL A O   1 
ATOM   536  C  CB  . VAL A 1 125 ? 174.063 181.322 160.809 1.00 101.51 ? 125 VAL A CB  1 
ATOM   537  C  CG1 . VAL A 1 125 ? 172.680 181.601 160.246 1.00 101.51 ? 125 VAL A CG1 1 
ATOM   538  C  CG2 . VAL A 1 125 ? 174.521 179.948 160.363 1.00 101.51 ? 125 VAL A CG2 1 
ATOM   539  N  N   . CYS A 1 126 ? 174.178 184.320 161.555 1.00 99.89  ? 126 CYS A N   1 
ATOM   540  C  CA  . CYS A 1 126 ? 173.555 185.636 161.696 1.00 99.89  ? 126 CYS A CA  1 
ATOM   541  C  C   . CYS A 1 126 ? 174.100 186.289 162.956 1.00 99.89  ? 126 CYS A C   1 
ATOM   542  O  O   . CYS A 1 126 ? 173.609 186.027 164.065 1.00 99.89  ? 126 CYS A O   1 
ATOM   543  C  CB  . CYS A 1 126 ? 172.033 185.537 161.747 1.00 99.89  ? 126 CYS A CB  1 
ATOM   544  S  SG  . CYS A 1 126 ? 171.200 187.132 161.784 1.00 99.89  ? 126 CYS A SG  1 
ATOM   545  N  N   . PRO A 1 127 ? 175.112 187.153 162.829 1.00 103.36 ? 127 PRO A N   1 
ATOM   546  C  CA  . PRO A 1 127 ? 175.758 187.727 164.024 1.00 103.36 ? 127 PRO A CA  1 
ATOM   547  C  C   . PRO A 1 127 ? 174.856 188.620 164.860 1.00 103.36 ? 127 PRO A C   1 
ATOM   548  O  O   . PRO A 1 127 ? 175.171 188.860 166.032 1.00 103.36 ? 127 PRO A O   1 
ATOM   549  C  CB  . PRO A 1 127 ? 176.935 188.521 163.439 1.00 103.36 ? 127 PRO A CB  1 
ATOM   550  C  CG  . PRO A 1 127 ? 177.143 187.960 162.067 1.00 103.36 ? 127 PRO A CG  1 
ATOM   551  C  CD  . PRO A 1 127 ? 175.784 187.568 161.588 1.00 103.36 ? 127 PRO A CD  1 
ATOM   552  N  N   . LEU A 1 128 ? 173.756 189.130 164.302 1.00 97.68  ? 128 LEU A N   1 
ATOM   553  C  CA  . LEU A 1 128 ? 172.814 189.899 165.107 1.00 97.68  ? 128 LEU A CA  1 
ATOM   554  C  C   . LEU A 1 128 ? 172.097 189.004 166.110 1.00 97.68  ? 128 LEU A C   1 
ATOM   555  O  O   . LEU A 1 128 ? 172.001 189.336 167.297 1.00 97.68  ? 128 LEU A O   1 
ATOM   556  C  CB  . LEU A 1 128 ? 171.807 190.610 164.205 1.00 97.68  ? 128 LEU A CB  1 
ATOM   557  C  CG  . LEU A 1 128 ? 170.536 191.115 164.888 1.00 97.68  ? 128 LEU A CG  1 
ATOM   558  C  CD1 . LEU A 1 128 ? 170.827 192.365 165.692 1.00 97.68  ? 128 LEU A CD1 1 
ATOM   559  C  CD2 . LEU A 1 128 ? 169.444 191.380 163.867 1.00 97.68  ? 128 LEU A CD2 1 
ATOM   560  N  N   . PHE A 1 129 ? 171.599 187.859 165.655 1.00 90.20  ? 129 PHE A N   1 
ATOM   561  C  CA  . PHE A 1 129 ? 170.888 186.920 166.522 1.00 90.20  ? 129 PHE A CA  1 
ATOM   562  C  C   . PHE A 1 129 ? 171.828 185.867 167.095 1.00 90.20  ? 129 PHE A C   1 
ATOM   563  O  O   . PHE A 1 129 ? 171.578 184.668 167.001 1.00 90.20  ? 129 PHE A O   1 
ATOM   564  C  CB  . PHE A 1 129 ? 169.748 186.269 165.751 1.00 90.20  ? 129 PHE A CB  1 
ATOM   565  C  CG  . PHE A 1 129 ? 168.495 187.088 165.720 1.00 90.20  ? 129 PHE A CG  1 
ATOM   566  C  CD1 . PHE A 1 129 ? 167.972 187.620 166.883 1.00 90.20  ? 129 PHE A CD1 1 
ATOM   567  C  CD2 . PHE A 1 129 ? 167.847 187.337 164.524 1.00 90.20  ? 129 PHE A CD2 1 
ATOM   568  C  CE1 . PHE A 1 129 ? 166.820 188.379 166.853 1.00 90.20  ? 129 PHE A CE1 1 
ATOM   569  C  CE2 . PHE A 1 129 ? 166.694 188.093 164.489 1.00 90.20  ? 129 PHE A CE2 1 
ATOM   570  C  CZ  . PHE A 1 129 ? 166.180 188.615 165.654 1.00 90.20  ? 129 PHE A CZ  1 
ATOM   571  N  N   . GLU A 1 130 ? 172.929 186.315 167.695 1.00 97.47  ? 130 GLU A N   1 
ATOM   572  C  CA  . GLU A 1 130 ? 173.858 185.405 168.352 1.00 97.47  ? 130 GLU A CA  1 
ATOM   573  C  C   . GLU A 1 130 ? 173.413 185.042 169.761 1.00 97.47  ? 130 GLU A C   1 
ATOM   574  O  O   . GLU A 1 130 ? 173.914 184.062 170.323 1.00 97.47  ? 130 GLU A O   1 
ATOM   575  C  CB  . GLU A 1 130 ? 175.255 186.029 168.387 1.00 97.47  ? 130 GLU A CB  1 
ATOM   576  C  CG  . GLU A 1 130 ? 176.400 185.049 168.578 1.00 97.47  ? 130 GLU A CG  1 
ATOM   577  C  CD  . GLU A 1 130 ? 177.749 185.677 168.301 1.00 97.47  ? 130 GLU A CD  1 
ATOM   578  O  OE1 . GLU A 1 130 ? 177.850 186.471 167.343 1.00 97.47  ? 130 GLU A OE1 1 
ATOM   579  O  OE2 . GLU A 1 130 ? 178.709 185.377 169.041 1.00 97.47  ? 130 GLU A OE2 1 
ATOM   580  N  N   . GLY A 1 131 ? 172.463 185.782 170.330 1.00 91.23  ? 131 GLY A N   1 
ATOM   581  C  CA  . GLY A 1 131 ? 171.988 185.508 171.672 1.00 91.23  ? 131 GLY A CA  1 
ATOM   582  C  C   . GLY A 1 131 ? 171.188 184.232 171.809 1.00 91.23  ? 131 GLY A C   1 
ATOM   583  O  O   . GLY A 1 131 ? 170.941 183.801 172.941 1.00 91.23  ? 131 GLY A O   1 
ATOM   584  N  N   . ILE A 1 132 ? 170.767 183.629 170.695 1.00 86.54  ? 132 ILE A N   1 
ATOM   585  C  CA  . ILE A 1 132 ? 170.061 182.355 170.758 1.00 86.54  ? 132 ILE A CA  1 
ATOM   586  C  C   . ILE A 1 132 ? 170.983 181.255 171.265 1.00 86.54  ? 132 ILE A C   1 
ATOM   587  O  O   . ILE A 1 132 ? 170.548 180.366 172.005 1.00 86.54  ? 132 ILE A O   1 
ATOM   588  C  CB  . ILE A 1 132 ? 169.464 182.005 169.383 1.00 86.54  ? 132 ILE A CB  1 
ATOM   589  C  CG1 . ILE A 1 132 ? 168.736 183.216 168.798 1.00 86.54  ? 132 ILE A CG1 1 
ATOM   590  C  CG2 . ILE A 1 132 ? 168.521 180.820 169.493 1.00 86.54  ? 132 ILE A CG2 1 
ATOM   591  C  CD1 . ILE A 1 132 ? 167.987 182.927 167.516 1.00 86.54  ? 132 ILE A CD1 1 
ATOM   592  N  N   . GLY A 1 133 ? 172.261 181.295 170.888 1.00 90.59  ? 133 GLY A N   1 
ATOM   593  C  CA  . GLY A 1 133 ? 173.200 180.303 171.386 1.00 90.59  ? 133 GLY A CA  1 
ATOM   594  C  C   . GLY A 1 133 ? 173.450 180.420 172.879 1.00 90.59  ? 133 GLY A C   1 
ATOM   595  O  O   . GLY A 1 133 ? 173.524 179.410 173.588 1.00 90.59  ? 133 GLY A O   1 
ATOM   596  N  N   . TYR A 1 134 ? 173.574 181.650 173.379 1.00 90.40  ? 134 TYR A N   1 
ATOM   597  C  CA  . TYR A 1 134 ? 173.808 181.845 174.806 1.00 90.40  ? 134 TYR A CA  1 
ATOM   598  C  C   . TYR A 1 134 ? 172.584 181.463 175.630 1.00 90.40  ? 134 TYR A C   1 
ATOM   599  O  O   . TYR A 1 134 ? 172.724 180.966 176.755 1.00 90.40  ? 134 TYR A O   1 
ATOM   600  C  CB  . TYR A 1 134 ? 174.209 183.294 175.071 1.00 90.40  ? 134 TYR A CB  1 
ATOM   601  C  CG  . TYR A 1 134 ? 175.656 183.605 174.757 1.00 90.40  ? 134 TYR A CG  1 
ATOM   602  C  CD1 . TYR A 1 134 ? 176.504 182.634 174.239 1.00 90.40  ? 134 TYR A CD1 1 
ATOM   603  C  CD2 . TYR A 1 134 ? 176.173 184.874 174.977 1.00 90.40  ? 134 TYR A CD2 1 
ATOM   604  C  CE1 . TYR A 1 134 ? 177.824 182.917 173.950 1.00 90.40  ? 134 TYR A CE1 1 
ATOM   605  C  CE2 . TYR A 1 134 ? 177.492 185.166 174.693 1.00 90.40  ? 134 TYR A CE2 1 
ATOM   606  C  CZ  . TYR A 1 134 ? 178.312 184.184 174.180 1.00 90.40  ? 134 TYR A CZ  1 
ATOM   607  O  OH  . TYR A 1 134 ? 179.627 184.471 173.895 1.00 90.40  ? 134 TYR A OH  1 
ATOM   608  N  N   . ALA A 1 135 ? 171.384 181.674 175.084 1.00 87.02  ? 135 ALA A N   1 
ATOM   609  C  CA  . ALA A 1 135 ? 170.174 181.200 175.747 1.00 87.02  ? 135 ALA A CA  1 
ATOM   610  C  C   . ALA A 1 135 ? 170.163 179.681 175.844 1.00 87.02  ? 135 ALA A C   1 
ATOM   611  O  O   . ALA A 1 135 ? 169.749 179.120 176.865 1.00 87.02  ? 135 ALA A O   1 
ATOM   612  C  CB  . ALA A 1 135 ? 168.937 181.700 175.005 1.00 87.02  ? 135 ALA A CB  1 
ATOM   613  N  N   . THR A 1 136 ? 170.628 178.998 174.795 1.00 87.19  ? 136 THR A N   1 
ATOM   614  C  CA  . THR A 1 136 ? 170.750 177.547 174.867 1.00 87.19  ? 136 THR A CA  1 
ATOM   615  C  C   . THR A 1 136 ? 171.809 177.121 175.875 1.00 87.19  ? 136 THR A C   1 
ATOM   616  O  O   . THR A 1 136 ? 171.653 176.083 176.525 1.00 87.19  ? 136 THR A O   1 
ATOM   617  C  CB  . THR A 1 136 ? 171.063 176.964 173.491 1.00 87.19  ? 136 THR A CB  1 
ATOM   618  O  OG1 . THR A 1 136 ? 172.255 177.560 172.971 1.00 87.19  ? 136 THR A OG1 1 
ATOM   619  C  CG2 . THR A 1 136 ? 169.912 177.205 172.532 1.00 87.19  ? 136 THR A CG2 1 
ATOM   620  N  N   . GLN A 1 137 ? 172.878 177.908 176.033 1.00 89.12  ? 137 GLN A N   1 
ATOM   621  C  CA  . GLN A 1 137 ? 173.853 177.623 177.086 1.00 89.12  ? 137 GLN A CA  1 
ATOM   622  C  C   . GLN A 1 137 ? 173.228 177.728 178.471 1.00 89.12  ? 137 GLN A C   1 
ATOM   623  O  O   . GLN A 1 137 ? 173.493 176.892 179.344 1.00 89.12  ? 137 GLN A O   1 
ATOM   624  C  CB  . GLN A 1 137 ? 175.045 178.572 176.989 1.00 89.12  ? 137 GLN A CB  1 
ATOM   625  C  CG  . GLN A 1 137 ? 175.873 178.497 175.719 1.00 89.12  ? 137 GLN A CG  1 
ATOM   626  C  CD  . GLN A 1 137 ? 176.607 177.178 175.525 1.00 89.12  ? 137 GLN A CD  1 
ATOM   627  O  OE1 . GLN A 1 137 ? 176.005 176.126 175.301 1.00 89.12  ? 137 GLN A OE1 1 
ATOM   628  N  NE2 . GLN A 1 137 ? 177.929 177.233 175.624 1.00 89.12  ? 137 GLN A NE2 1 
ATOM   629  N  N   . VAL A 1 138 ? 172.409 178.757 178.695 1.00 81.75  ? 138 VAL A N   1 
ATOM   630  C  CA  . VAL A 1 138 ? 171.768 178.918 179.999 1.00 81.75  ? 138 VAL A CA  1 
ATOM   631  C  C   . VAL A 1 138 ? 170.769 177.791 180.250 1.00 81.75  ? 138 VAL A C   1 
ATOM   632  O  O   . VAL A 1 138 ? 170.668 177.269 181.370 1.00 81.75  ? 138 VAL A O   1 
ATOM   633  C  CB  . VAL A 1 138 ? 171.108 180.304 180.107 1.00 81.75  ? 138 VAL A CB  1 
ATOM   634  C  CG1 . VAL A 1 138 ? 170.440 180.471 181.455 1.00 81.75  ? 138 VAL A CG1 1 
ATOM   635  C  CG2 . VAL A 1 138 ? 172.143 181.392 179.918 1.00 81.75  ? 138 VAL A CG2 1 
ATOM   636  N  N   . ILE A 1 139 ? 170.031 177.389 179.210 1.00 79.41  ? 139 ILE A N   1 
ATOM   637  C  CA  . ILE A 1 139 ? 169.099 176.269 179.336 1.00 79.41  ? 139 ILE A CA  1 
ATOM   638  C  C   . ILE A 1 139 ? 169.849 174.983 179.662 1.00 79.41  ? 139 ILE A C   1 
ATOM   639  O  O   . ILE A 1 139 ? 169.419 174.199 180.515 1.00 79.41  ? 139 ILE A O   1 
ATOM   640  C  CB  . ILE A 1 139 ? 168.255 176.130 178.054 1.00 79.41  ? 139 ILE A CB  1 
ATOM   641  C  CG1 . ILE A 1 139 ? 167.263 177.283 177.944 1.00 79.41  ? 139 ILE A CG1 1 
ATOM   642  C  CG2 . ILE A 1 139 ? 167.492 174.821 178.039 1.00 79.41  ? 139 ILE A CG2 1 
ATOM   643  C  CD1 . ILE A 1 139 ? 166.422 177.248 176.695 1.00 79.41  ? 139 ILE A CD1 1 
ATOM   644  N  N   . GLU A 1 140 ? 170.994 174.762 179.010 1.00 84.49  ? 140 GLU A N   1 
ATOM   645  C  CA  . GLU A 1 140 ? 171.797 173.575 179.291 1.00 84.49  ? 140 GLU A CA  1 
ATOM   646  C  C   . GLU A 1 140 ? 172.346 173.595 180.711 1.00 84.49  ? 140 GLU A C   1 
ATOM   647  O  O   . GLU A 1 140 ? 172.410 172.551 181.370 1.00 84.49  ? 140 GLU A O   1 
ATOM   648  C  CB  . GLU A 1 140 ? 172.943 173.463 178.288 1.00 84.49  ? 140 GLU A CB  1 
ATOM   649  C  CG  . GLU A 1 140 ? 172.555 172.819 176.980 1.00 84.49  ? 140 GLU A CG  1 
ATOM   650  C  CD  . GLU A 1 140 ? 172.168 171.368 177.135 1.00 84.49  ? 140 GLU A CD  1 
ATOM   651  O  OE1 . GLU A 1 140 ? 172.740 170.689 178.012 1.00 84.49  ? 140 GLU A OE1 1 
ATOM   652  O  OE2 . GLU A 1 140 ? 171.289 170.905 176.380 1.00 84.49  ? 140 GLU A OE2 1 
ATOM   653  N  N   . ALA A 1 141 ? 172.764 174.769 181.192 1.00 81.26  ? 141 ALA A N   1 
ATOM   654  C  CA  . ALA A 1 141 ? 173.274 174.870 182.556 1.00 81.26  ? 141 ALA A CA  1 
ATOM   655  C  C   . ALA A 1 141 ? 172.186 174.566 183.578 1.00 81.26  ? 141 ALA A C   1 
ATOM   656  O  O   . ALA A 1 141 ? 172.414 173.809 184.529 1.00 81.26  ? 141 ALA A O   1 
ATOM   657  C  CB  . ALA A 1 141 ? 173.864 176.258 182.797 1.00 81.26  ? 141 ALA A CB  1 
ATOM   658  N  N   . HIS A 1 142 ? 170.986 175.124 183.380 1.00 78.22  ? 142 HIS A N   1 
ATOM   659  C  CA  . HIS A 1 142 ? 169.872 174.826 184.278 1.00 78.22  ? 142 HIS A CA  1 
ATOM   660  C  C   . HIS A 1 142 ? 169.497 173.350 184.226 1.00 78.22  ? 142 HIS A C   1 
ATOM   661  O  O   . HIS A 1 142 ? 169.247 172.726 185.269 1.00 78.22  ? 142 HIS A O   1 
ATOM   662  C  CB  . HIS A 1 142 ? 168.664 175.691 183.927 1.00 78.22  ? 142 HIS A CB  1 
ATOM   663  C  CG  . HIS A 1 142 ? 168.836 177.136 184.270 1.00 78.22  ? 142 HIS A CG  1 
ATOM   664  N  ND1 . HIS A 1 142 ? 168.032 178.125 183.747 1.00 78.22  ? 142 HIS A ND1 1 
ATOM   665  C  CD2 . HIS A 1 142 ? 169.714 177.759 185.090 1.00 78.22  ? 142 HIS A CD2 1 
ATOM   666  C  CE1 . HIS A 1 142 ? 168.411 179.296 184.224 1.00 78.22  ? 142 HIS A CE1 1 
ATOM   667  N  NE2 . HIS A 1 142 ? 169.429 179.102 185.042 1.00 78.22  ? 142 HIS A NE2 1 
ATOM   668  N  N   . LEU A 1 143 ? 169.473 172.773 183.021 1.00 77.90  ? 143 LEU A N   1 
ATOM   669  C  CA  . LEU A 1 143 ? 169.153 171.359 182.871 1.00 77.90  ? 143 LEU A CA  1 
ATOM   670  C  C   . LEU A 1 143 ? 170.157 170.491 183.613 1.00 77.90  ? 143 LEU A C   1 
ATOM   671  O  O   . LEU A 1 143 ? 169.777 169.708 184.486 1.00 77.90  ? 143 LEU A O   1 
ATOM   672  C  CB  . LEU A 1 143 ? 169.104 170.990 181.391 1.00 77.90  ? 143 LEU A CB  1 
ATOM   673  C  CG  . LEU A 1 143 ? 168.594 169.582 181.106 1.00 77.90  ? 143 LEU A CG  1 
ATOM   674  C  CD1 . LEU A 1 143 ? 167.197 169.434 181.652 1.00 77.90  ? 143 LEU A CD1 1 
ATOM   675  C  CD2 . LEU A 1 143 ? 168.614 169.305 179.617 1.00 77.90  ? 143 LEU A CD2 1 
ATOM   676  N  N   . ASN A 1 144 ? 171.453 170.691 183.352 1.00 83.47  ? 144 ASN A N   1 
ATOM   677  C  CA  . ASN A 1 144 ? 172.494 169.944 184.052 1.00 83.47  ? 144 ASN A CA  1 
ATOM   678  C  C   . ASN A 1 144 ? 172.483 170.194 185.553 1.00 83.47  ? 144 ASN A C   1 
ATOM   679  O  O   . ASN A 1 144 ? 172.999 169.366 186.310 1.00 83.47  ? 144 ASN A O   1 
ATOM   680  C  CB  . ASN A 1 144 ? 173.868 170.293 183.482 1.00 83.47  ? 144 ASN A CB  1 
ATOM   681  C  CG  . ASN A 1 144 ? 174.120 169.642 182.140 1.00 83.47  ? 144 ASN A CG  1 
ATOM   682  O  OD1 . ASN A 1 144 ? 173.301 168.866 181.652 1.00 83.47  ? 144 ASN A OD1 1 
ATOM   683  N  ND2 . ASN A 1 144 ? 175.258 169.957 181.534 1.00 83.47  ? 144 ASN A ND2 1 
ATOM   684  N  N   . VAL A 1 145 ? 171.914 171.314 186.003 1.00 77.65  ? 145 VAL A N   1 
ATOM   685  C  CA  . VAL A 1 145 ? 171.682 171.485 187.431 1.00 77.65  ? 145 VAL A CA  1 
ATOM   686  C  C   . VAL A 1 145 ? 170.607 170.516 187.921 1.00 77.65  ? 145 VAL A C   1 
ATOM   687  O  O   . VAL A 1 145 ? 170.807 169.815 188.920 1.00 77.65  ? 145 VAL A O   1 
ATOM   688  C  CB  . VAL A 1 145 ? 171.336 172.950 187.754 1.00 77.65  ? 145 VAL A CB  1 
ATOM   689  C  CG1 . VAL A 1 145 ? 170.595 173.056 189.073 1.00 77.65  ? 145 VAL A CG1 1 
ATOM   690  C  CG2 . VAL A 1 145 ? 172.602 173.786 187.809 1.00 77.65  ? 145 VAL A CG2 1 
ATOM   691  N  N   . TYR A 1 146 ? 169.461 170.427 187.229 1.00 75.52  ? 146 TYR A N   1 
ATOM   692  C  CA  . TYR A 1 146 ? 168.405 169.564 187.767 1.00 75.52  ? 146 TYR A CA  1 
ATOM   693  C  C   . TYR A 1 146 ? 168.098 168.312 186.949 1.00 75.52  ? 146 TYR A C   1 
ATOM   694  O  O   . TYR A 1 146 ? 167.143 167.606 187.283 1.00 75.52  ? 146 TYR A O   1 
ATOM   695  C  CB  . TYR A 1 146 ? 167.086 170.329 188.000 1.00 75.52  ? 146 TYR A CB  1 
ATOM   696  C  CG  . TYR A 1 146 ? 166.286 170.775 186.790 1.00 75.52  ? 146 TYR A CG  1 
ATOM   697  C  CD1 . TYR A 1 146 ? 166.435 172.042 186.259 1.00 75.52  ? 146 TYR A CD1 1 
ATOM   698  C  CD2 . TYR A 1 146 ? 165.338 169.935 186.213 1.00 75.52  ? 146 TYR A CD2 1 
ATOM   699  C  CE1 . TYR A 1 146 ? 165.693 172.447 185.169 1.00 75.52  ? 146 TYR A CE1 1 
ATOM   700  C  CE2 . TYR A 1 146 ? 164.599 170.326 185.127 1.00 75.52  ? 146 TYR A CE2 1 
ATOM   701  C  CZ  . TYR A 1 146 ? 164.776 171.581 184.610 1.00 75.52  ? 146 TYR A CZ  1 
ATOM   702  O  OH  . TYR A 1 146 ? 164.027 171.970 183.527 1.00 75.52  ? 146 TYR A OH  1 
ATOM   703  N  N   . TYR A 1 147 ? 168.848 168.002 185.897 1.00 86.88  ? 147 TYR A N   1 
ATOM   704  C  CA  . TYR A 1 147 ? 168.610 166.721 185.237 1.00 86.88  ? 147 TYR A CA  1 
ATOM   705  C  C   . TYR A 1 147 ? 169.298 165.572 185.955 1.00 86.88  ? 147 TYR A C   1 
ATOM   706  O  O   . TYR A 1 147 ? 168.981 164.409 185.687 1.00 86.88  ? 147 TYR A O   1 
ATOM   707  C  CB  . TYR A 1 147 ? 169.079 166.777 183.783 1.00 86.88  ? 147 TYR A CB  1 
ATOM   708  C  CG  . TYR A 1 147 ? 168.605 165.665 182.887 1.00 86.88  ? 147 TYR A CG  1 
ATOM   709  C  CD1 . TYR A 1 147 ? 167.302 165.641 182.406 1.00 86.88  ? 147 TYR A CD1 1 
ATOM   710  C  CD2 . TYR A 1 147 ? 169.473 164.661 182.489 1.00 86.88  ? 147 TYR A CD2 1 
ATOM   711  C  CE1 . TYR A 1 147 ? 166.875 164.633 181.568 1.00 86.88  ? 147 TYR A CE1 1 
ATOM   712  C  CE2 . TYR A 1 147 ? 169.057 163.652 181.657 1.00 86.88  ? 147 TYR A CE2 1 
ATOM   713  C  CZ  . TYR A 1 147 ? 167.759 163.642 181.198 1.00 86.88  ? 147 TYR A CZ  1 
ATOM   714  O  OH  . TYR A 1 147 ? 167.354 162.630 180.362 1.00 86.88  ? 147 TYR A OH  1 
ATOM   715  N  N   . ILE A 1 148 ? 170.220 165.875 186.868 1.00 81.88  ? 148 ILE A N   1 
ATOM   716  C  CA  . ILE A 1 148 ? 170.973 164.846 187.571 1.00 81.88  ? 148 ILE A CA  1 
ATOM   717  C  C   . ILE A 1 148 ? 170.275 164.392 188.851 1.00 81.88  ? 148 ILE A C   1 
ATOM   718  O  O   . ILE A 1 148 ? 170.580 163.304 189.359 1.00 81.88  ? 148 ILE A O   1 
ATOM   719  C  CB  . ILE A 1 148 ? 172.398 165.366 187.854 1.00 81.88  ? 148 ILE A CB  1 
ATOM   720  C  CG1 . ILE A 1 148 ? 173.370 164.222 188.144 1.00 81.88  ? 148 ILE A CG1 1 
ATOM   721  C  CG2 . ILE A 1 148 ? 172.400 166.386 188.978 1.00 81.88  ? 148 ILE A CG2 1 
ATOM   722  C  CD1 . ILE A 1 148 ? 173.571 163.295 186.981 1.00 81.88  ? 148 ILE A CD1 1 
ATOM   723  N  N   . ILE A 1 149 ? 169.326 165.177 189.369 1.00 74.85  ? 149 ILE A N   1 
ATOM   724  C  CA  . ILE A 1 149 ? 168.661 164.810 190.615 1.00 74.85  ? 149 ILE A CA  1 
ATOM   725  C  C   . ILE A 1 149 ? 167.728 163.620 190.402 1.00 74.85  ? 149 ILE A C   1 
ATOM   726  O  O   . ILE A 1 149 ? 167.483 162.841 191.333 1.00 74.85  ? 149 ILE A O   1 
ATOM   727  C  CB  . ILE A 1 149 ? 167.929 166.032 191.206 1.00 74.85  ? 149 ILE A CB  1 
ATOM   728  C  CG1 . ILE A 1 149 ? 167.377 165.723 192.595 1.00 74.85  ? 149 ILE A CG1 1 
ATOM   729  C  CG2 . ILE A 1 149 ? 166.812 166.495 190.306 1.00 74.85  ? 149 ILE A CG2 1 
ATOM   730  C  CD1 . ILE A 1 149 ? 166.724 166.891 193.254 1.00 74.85  ? 149 ILE A CD1 1 
ATOM   731  N  N   . ILE A 1 150 ? 167.215 163.439 189.181 1.00 73.51  ? 150 ILE A N   1 
ATOM   732  C  CA  . ILE A 1 150 ? 166.395 162.268 188.881 1.00 73.51  ? 150 ILE A CA  1 
ATOM   733  C  C   . ILE A 1 150 ? 167.227 161.000 189.000 1.00 73.51  ? 150 ILE A C   1 
ATOM   734  O  O   . ILE A 1 150 ? 166.754 159.967 189.490 1.00 73.51  ? 150 ILE A O   1 
ATOM   735  C  CB  . ILE A 1 150 ? 165.770 162.403 187.483 1.00 73.51  ? 150 ILE A CB  1 
ATOM   736  C  CG1 . ILE A 1 150 ? 165.117 163.771 187.332 1.00 73.51  ? 150 ILE A CG1 1 
ATOM   737  C  CG2 . ILE A 1 150 ? 164.750 161.312 187.248 1.00 73.51  ? 150 ILE A CG2 1 
ATOM   738  C  CD1 . ILE A 1 150 ? 164.951 164.192 185.901 1.00 73.51  ? 150 ILE A CD1 1 
ATOM   739  N  N   . LEU A 1 151 ? 168.487 161.066 188.570 1.00 77.27  ? 151 LEU A N   1 
ATOM   740  C  CA  . LEU A 1 151 ? 169.389 159.941 188.768 1.00 77.27  ? 151 LEU A CA  1 
ATOM   741  C  C   . LEU A 1 151 ? 169.732 159.750 190.237 1.00 77.27  ? 151 LEU A C   1 
ATOM   742  O  O   . LEU A 1 151 ? 169.976 158.619 190.662 1.00 77.27  ? 151 LEU A O   1 
ATOM   743  C  CB  . LEU A 1 151 ? 170.651 160.132 187.935 1.00 77.27  ? 151 LEU A CB  1 
ATOM   744  C  CG  . LEU A 1 151 ? 170.333 160.225 186.446 1.00 77.27  ? 151 LEU A CG  1 
ATOM   745  C  CD1 . LEU A 1 151 ? 171.587 160.455 185.638 1.00 77.27  ? 151 LEU A CD1 1 
ATOM   746  C  CD2 . LEU A 1 151 ? 169.622 158.966 185.991 1.00 77.27  ? 151 LEU A CD2 1 
ATOM   747  N  N   . ALA A 1 152 ? 169.736 160.825 191.030 1.00 73.54  ? 152 ALA A N   1 
ATOM   748  C  CA  . ALA A 1 152 ? 169.941 160.674 192.468 1.00 73.54  ? 152 ALA A CA  1 
ATOM   749  C  C   . ALA A 1 152 ? 168.784 159.924 193.117 1.00 73.54  ? 152 ALA A C   1 
ATOM   750  O  O   . ALA A 1 152 ? 169.002 159.017 193.932 1.00 73.54  ? 152 ALA A O   1 
ATOM   751  C  CB  . ALA A 1 152 ? 170.130 162.040 193.122 1.00 73.54  ? 152 ALA A CB  1 
ATOM   752  N  N   . TRP A 1 153 ? 167.548 160.273 192.753 1.00 67.89  ? 153 TRP A N   1 
ATOM   753  C  CA  . TRP A 1 153 ? 166.390 159.547 193.263 1.00 67.89  ? 153 TRP A CA  1 
ATOM   754  C  C   . TRP A 1 153 ? 166.384 158.103 192.779 1.00 67.89  ? 153 TRP A C   1 
ATOM   755  O  O   . TRP A 1 153 ? 166.036 157.191 193.539 1.00 67.89  ? 153 TRP A O   1 
ATOM   756  C  CB  . TRP A 1 153 ? 165.102 160.251 192.849 1.00 67.89  ? 153 TRP A CB  1 
ATOM   757  C  CG  . TRP A 1 153 ? 164.898 161.568 193.510 1.00 67.89  ? 153 TRP A CG  1 
ATOM   758  C  CD1 . TRP A 1 153 ? 165.329 161.938 194.748 1.00 67.89  ? 153 TRP A CD1 1 
ATOM   759  C  CD2 . TRP A 1 153 ? 164.209 162.700 192.970 1.00 67.89  ? 153 TRP A CD2 1 
ATOM   760  N  NE1 . TRP A 1 153 ? 164.950 163.230 195.014 1.00 67.89  ? 153 TRP A NE1 1 
ATOM   761  C  CE2 . TRP A 1 153 ? 164.262 163.720 193.936 1.00 67.89  ? 153 TRP A CE2 1 
ATOM   762  C  CE3 . TRP A 1 153 ? 163.553 162.948 191.762 1.00 67.89  ? 153 TRP A CE3 1 
ATOM   763  C  CZ2 . TRP A 1 153 ? 163.684 164.967 193.733 1.00 67.89  ? 153 TRP A CZ2 1 
ATOM   764  C  CZ3 . TRP A 1 153 ? 162.982 164.186 191.562 1.00 67.89  ? 153 TRP A CZ3 1 
ATOM   765  C  CH2 . TRP A 1 153 ? 163.050 165.180 192.541 1.00 67.89  ? 153 TRP A CH2 1 
ATOM   766  N  N   . ALA A 1 154 ? 166.765 157.874 191.520 1.00 72.77  ? 154 ALA A N   1 
ATOM   767  C  CA  . ALA A 1 154 ? 166.791 156.512 191.001 1.00 72.77  ? 154 ALA A CA  1 
ATOM   768  C  C   . ALA A 1 154 ? 167.896 155.679 191.644 1.00 72.77  ? 154 ALA A C   1 
ATOM   769  O  O   . ALA A 1 154 ? 167.738 154.463 191.800 1.00 72.77  ? 154 ALA A O   1 
ATOM   770  C  CB  . ALA A 1 154 ? 166.944 156.535 189.482 1.00 72.77  ? 154 ALA A CB  1 
ATOM   771  N  N   . ILE A 1 155 ? 169.014 156.304 192.015 1.00 72.26  ? 155 ILE A N   1 
ATOM   772  C  CA  . ILE A 1 155 ? 170.041 155.609 192.782 1.00 72.26  ? 155 ILE A CA  1 
ATOM   773  C  C   . ILE A 1 155 ? 169.525 155.282 194.178 1.00 72.26  ? 155 ILE A C   1 
ATOM   774  O  O   . ILE A 1 155 ? 169.765 154.186 194.701 1.00 72.26  ? 155 ILE A O   1 
ATOM   775  C  CB  . ILE A 1 155 ? 171.331 156.453 192.822 1.00 72.26  ? 155 ILE A CB  1 
ATOM   776  C  CG1 . ILE A 1 155 ? 172.127 156.274 191.532 1.00 72.26  ? 155 ILE A CG1 1 
ATOM   777  C  CG2 . ILE A 1 155 ? 172.216 156.074 193.992 1.00 72.26  ? 155 ILE A CG2 1 
ATOM   778  C  CD1 . ILE A 1 155 ? 173.138 157.369 191.283 1.00 72.26  ? 155 ILE A CD1 1 
ATOM   779  N  N   . PHE A 1 156 ? 168.788 156.216 194.791 1.00 69.74  ? 156 PHE A N   1 
ATOM   780  C  CA  . PHE A 1 156 ? 168.243 155.974 196.126 1.00 69.74  ? 156 PHE A CA  1 
ATOM   781  C  C   . PHE A 1 156 ? 167.233 154.833 196.126 1.00 69.74  ? 156 PHE A C   1 
ATOM   782  O  O   . PHE A 1 156 ? 167.194 154.033 197.068 1.00 69.74  ? 156 PHE A O   1 
ATOM   783  C  CB  . PHE A 1 156 ? 167.603 157.242 196.684 1.00 69.74  ? 156 PHE A CB  1 
ATOM   784  C  CG  . PHE A 1 156 ? 166.910 157.030 197.994 1.00 69.74  ? 156 PHE A CG  1 
ATOM   785  C  CD1 . PHE A 1 156 ? 167.638 156.886 199.159 1.00 69.74  ? 156 PHE A CD1 1 
ATOM   786  C  CD2 . PHE A 1 156 ? 165.530 156.965 198.061 1.00 69.74  ? 156 PHE A CD2 1 
ATOM   787  C  CE1 . PHE A 1 156 ? 167.004 156.683 200.365 1.00 69.74  ? 156 PHE A CE1 1 
ATOM   788  C  CE2 . PHE A 1 156 ? 164.893 156.761 199.264 1.00 69.74  ? 156 PHE A CE2 1 
ATOM   789  C  CZ  . PHE A 1 156 ? 165.631 156.623 200.417 1.00 69.74  ? 156 PHE A CZ  1 
ATOM   790  N  N   . TYR A 1 157 ? 166.390 154.754 195.094 1.00 68.60  ? 157 TYR A N   1 
ATOM   791  C  CA  . TYR A 1 157 ? 165.556 153.568 194.920 1.00 68.60  ? 157 TYR A CA  1 
ATOM   792  C  C   . TYR A 1 157 ? 166.390 152.316 194.683 1.00 68.60  ? 157 TYR A C   1 
ATOM   793  O  O   . TYR A 1 157 ? 166.042 151.236 195.172 1.00 68.60  ? 157 TYR A O   1 
ATOM   794  C  CB  . TYR A 1 157 ? 164.562 153.770 193.781 1.00 68.60  ? 157 TYR A CB  1 
ATOM   795  C  CG  . TYR A 1 157 ? 163.311 154.524 194.154 1.00 68.60  ? 157 TYR A CG  1 
ATOM   796  C  CD1 . TYR A 1 157 ? 162.244 153.856 194.737 1.00 68.60  ? 157 TYR A CD1 1 
ATOM   797  C  CD2 . TYR A 1 157 ? 163.187 155.884 193.930 1.00 68.60  ? 157 TYR A CD2 1 
ATOM   798  C  CE1 . TYR A 1 157 ? 161.090 154.512 195.078 1.00 68.60  ? 157 TYR A CE1 1 
ATOM   799  C  CE2 . TYR A 1 157 ? 162.030 156.555 194.276 1.00 68.60  ? 157 TYR A CE2 1 
ATOM   800  C  CZ  . TYR A 1 157 ? 160.986 155.859 194.851 1.00 68.60  ? 157 TYR A CZ  1 
ATOM   801  O  OH  . TYR A 1 157 ? 159.827 156.507 195.201 1.00 68.60  ? 157 TYR A OH  1 
ATOM   802  N  N   . LEU A 1 158 ? 167.487 152.436 193.934 1.00 74.01  ? 158 LEU A N   1 
ATOM   803  C  CA  . LEU A 1 158 ? 168.352 151.282 193.713 1.00 74.01  ? 158 LEU A CA  1 
ATOM   804  C  C   . LEU A 1 158 ? 169.047 150.863 195.003 1.00 74.01  ? 158 LEU A C   1 
ATOM   805  O  O   . LEU A 1 158 ? 169.388 149.687 195.177 1.00 74.01  ? 158 LEU A O   1 
ATOM   806  C  CB  . LEU A 1 158 ? 169.376 151.598 192.624 1.00 74.01  ? 158 LEU A CB  1 
ATOM   807  C  CG  . LEU A 1 158 ? 170.167 150.429 192.040 1.00 74.01  ? 158 LEU A CG  1 
ATOM   808  C  CD1 . LEU A 1 158 ? 169.344 149.725 190.983 1.00 74.01  ? 158 LEU A CD1 1 
ATOM   809  C  CD2 . LEU A 1 158 ? 171.479 150.916 191.457 1.00 74.01  ? 158 LEU A CD2 1 
ATOM   810  N  N   . SER A 1 159 ? 169.262 151.812 195.918 1.00 75.70  ? 159 SER A N   1 
ATOM   811  C  CA  . SER A 1 159 ? 169.838 151.476 197.215 1.00 75.70  ? 159 SER A CA  1 
ATOM   812  C  C   . SER A 1 159 ? 168.877 150.638 198.046 1.00 75.70  ? 159 SER A C   1 
ATOM   813  O  O   . SER A 1 159 ? 169.286 149.666 198.692 1.00 75.70  ? 159 SER A O   1 
ATOM   814  C  CB  . SER A 1 159 ? 170.215 152.752 197.967 1.00 75.70  ? 159 SER A CB  1 
ATOM   815  O  OG  . SER A 1 159 ? 171.226 153.470 197.282 1.00 75.70  ? 159 SER A OG  1 
ATOM   816  N  N   . ASN A 1 160 ? 167.595 150.993 198.040 1.00 78.74  ? 160 ASN A N   1 
ATOM   817  C  CA  . ASN A 1 160 ? 166.605 150.286 198.839 1.00 78.74  ? 160 ASN A CA  1 
ATOM   818  C  C   . ASN A 1 160 ? 166.022 149.073 198.132 1.00 78.74  ? 160 ASN A C   1 
ATOM   819  O  O   . ASN A 1 160 ? 165.279 148.313 198.761 1.00 78.74  ? 160 ASN A O   1 
ATOM   820  C  CB  . ASN A 1 160 ? 165.471 151.235 199.230 1.00 78.74  ? 160 ASN A CB  1 
ATOM   821  C  CG  . ASN A 1 160 ? 165.950 152.396 200.068 1.00 78.74  ? 160 ASN A CG  1 
ATOM   822  O  OD1 . ASN A 1 160 ? 166.163 152.261 201.272 1.00 78.74  ? 160 ASN A OD1 1 
ATOM   823  N  ND2 . ASN A 1 160 ? 166.128 153.548 199.434 1.00 78.74  ? 160 ASN A ND2 1 
ATOM   824  N  N   . CYS A 1 161 ? 166.338 148.869 196.854 1.00 80.84  ? 161 CYS A N   1 
ATOM   825  C  CA  . CYS A 1 161 ? 165.701 147.799 196.096 1.00 80.84  ? 161 CYS A CA  1 
ATOM   826  C  C   . CYS A 1 161 ? 166.209 146.419 196.493 1.00 80.84  ? 161 CYS A C   1 
ATOM   827  O  O   . CYS A 1 161 ? 165.424 145.464 196.526 1.00 80.84  ? 161 CYS A O   1 
ATOM   828  C  CB  . CYS A 1 161 ? 165.911 148.019 194.600 1.00 80.84  ? 161 CYS A CB  1 
ATOM   829  S  SG  . CYS A 1 161 ? 165.324 146.664 193.578 1.00 80.84  ? 161 CYS A SG  1 
ATOM   830  N  N   . PHE A 1 162 ? 167.494 146.292 196.825 1.00 85.50  ? 162 PHE A N   1 
ATOM   831  C  CA  . PHE A 1 162 ? 168.082 144.985 197.098 1.00 85.50  ? 162 PHE A CA  1 
ATOM   832  C  C   . PHE A 1 162 ? 167.610 144.426 198.433 1.00 85.50  ? 162 PHE A C   1 
ATOM   833  O  O   . PHE A 1 162 ? 168.382 144.348 199.393 1.00 85.50  ? 162 PHE A O   1 
ATOM   834  C  CB  . PHE A 1 162 ? 169.608 145.067 197.080 1.00 85.50  ? 162 PHE A CB  1 
ATOM   835  C  CG  . PHE A 1 162 ? 170.175 145.478 195.757 1.00 85.50  ? 162 PHE A CG  1 
ATOM   836  C  CD1 . PHE A 1 162 ? 169.760 144.857 194.592 1.00 85.50  ? 162 PHE A CD1 1 
ATOM   837  C  CD2 . PHE A 1 162 ? 171.128 146.478 195.677 1.00 85.50  ? 162 PHE A CD2 1 
ATOM   838  C  CE1 . PHE A 1 162 ? 170.283 145.227 193.372 1.00 85.50  ? 162 PHE A CE1 1 
ATOM   839  C  CE2 . PHE A 1 162 ? 171.655 146.854 194.459 1.00 85.50  ? 162 PHE A CE2 1 
ATOM   840  C  CZ  . PHE A 1 162 ? 171.232 146.228 193.305 1.00 85.50  ? 162 PHE A CZ  1 
ATOM   841  N  N   . THR A 1 163 ? 166.341 144.034 198.494 1.00 87.00  ? 163 THR A N   1 
ATOM   842  C  CA  . THR A 1 163 ? 165.748 143.445 199.683 1.00 87.00  ? 163 THR A CA  1 
ATOM   843  C  C   . THR A 1 163 ? 164.668 142.487 199.204 1.00 87.00  ? 163 THR A C   1 
ATOM   844  O  O   . THR A 1 163 ? 163.991 142.765 198.211 1.00 87.00  ? 163 THR A O   1 
ATOM   845  C  CB  . THR A 1 163 ? 165.161 144.520 200.613 1.00 87.00  ? 163 THR A CB  1 
ATOM   846  O  OG1 . THR A 1 163 ? 166.156 145.512 200.895 1.00 87.00  ? 163 THR A OG1 1 
ATOM   847  C  CG2 . THR A 1 163 ? 164.713 143.916 201.938 1.00 87.00  ? 163 THR A CG2 1 
ATOM   848  N  N   . THR A 1 164 ? 164.522 141.354 199.899 1.00 89.46  ? 164 THR A N   1 
ATOM   849  C  CA  . THR A 1 164 ? 163.518 140.367 199.517 1.00 89.46  ? 164 THR A CA  1 
ATOM   850  C  C   . THR A 1 164 ? 162.095 140.896 199.658 1.00 89.46  ? 164 THR A C   1 
ATOM   851  O  O   . THR A 1 164 ? 161.186 140.378 199.000 1.00 89.46  ? 164 THR A O   1 
ATOM   852  C  CB  . THR A 1 164 ? 163.692 139.092 200.346 1.00 89.46  ? 164 THR A CB  1 
ATOM   853  O  OG1 . THR A 1 164 ? 162.629 138.178 200.051 1.00 89.46  ? 164 THR A OG1 1 
ATOM   854  C  CG2 . THR A 1 164 ? 163.694 139.410 201.835 1.00 89.46  ? 164 THR A CG2 1 
ATOM   855  N  N   . GLU A 1 165 ? 161.881 141.910 200.492 1.00 90.31  ? 165 GLU A N   1 
ATOM   856  C  CA  . GLU A 1 165 ? 160.611 142.616 200.577 1.00 90.31  ? 165 GLU A CA  1 
ATOM   857  C  C   . GLU A 1 165 ? 160.852 144.085 200.265 1.00 90.31  ? 165 GLU A C   1 
ATOM   858  O  O   . GLU A 1 165 ? 161.696 144.726 200.898 1.00 90.31  ? 165 GLU A O   1 
ATOM   859  C  CB  . GLU A 1 165 ? 159.979 142.457 201.961 1.00 90.31  ? 165 GLU A CB  1 
ATOM   860  C  CG  . GLU A 1 165 ? 158.484 142.721 201.989 1.00 90.31  ? 165 GLU A CG  1 
ATOM   861  C  CD  . GLU A 1 165 ? 157.700 141.716 201.167 1.00 90.31  ? 165 GLU A CD  1 
ATOM   862  O  OE1 . GLU A 1 165 ? 157.929 140.500 201.335 1.00 90.31  ? 165 GLU A OE1 1 
ATOM   863  O  OE2 . GLU A 1 165 ? 156.853 142.143 200.355 1.00 90.31  ? 165 GLU A OE2 1 
ATOM   864  N  N   . LEU A 1 166 ? 160.114 144.607 199.292 1.00 79.25  ? 166 LEU A N   1 
ATOM   865  C  CA  . LEU A 1 166 ? 160.324 145.976 198.847 1.00 79.25  ? 166 LEU A CA  1 
ATOM   866  C  C   . LEU A 1 166 ? 159.881 146.961 199.926 1.00 79.25  ? 166 LEU A C   1 
ATOM   867  O  O   . LEU A 1 166 ? 158.948 146.677 200.682 1.00 79.25  ? 166 LEU A O   1 
ATOM   868  C  CB  . LEU A 1 166 ? 159.555 146.234 197.555 1.00 79.25  ? 166 LEU A CB  1 
ATOM   869  C  CG  . LEU A 1 166 ? 160.155 145.609 196.301 1.00 79.25  ? 166 LEU A CG  1 
ATOM   870  C  CD1 . LEU A 1 166 ? 159.240 145.829 195.113 1.00 79.25  ? 166 LEU A CD1 1 
ATOM   871  C  CD2 . LEU A 1 166 ? 161.529 146.187 196.038 1.00 79.25  ? 166 LEU A CD2 1 
ATOM   872  N  N   . PRO A 1 167 ? 160.545 148.113 200.040 1.00 75.05  ? 167 PRO A N   1 
ATOM   873  C  CA  . PRO A 1 167 ? 160.114 149.109 201.033 1.00 75.05  ? 167 PRO A CA  1 
ATOM   874  C  C   . PRO A 1 167 ? 158.769 149.744 200.721 1.00 75.05  ? 167 PRO A C   1 
ATOM   875  O  O   . PRO A 1 167 ? 158.042 150.115 201.651 1.00 75.05  ? 167 PRO A O   1 
ATOM   876  C  CB  . PRO A 1 167 ? 161.244 150.148 201.000 1.00 75.05  ? 167 PRO A CB  1 
ATOM   877  C  CG  . PRO A 1 167 ? 162.400 149.449 200.368 1.00 75.05  ? 167 PRO A CG  1 
ATOM   878  C  CD  . PRO A 1 167 ? 161.805 148.497 199.388 1.00 75.05  ? 167 PRO A CD  1 
ATOM   879  N  N   . TRP A 1 168 ? 158.412 149.880 199.441 1.00 71.66  ? 168 TRP A N   1 
ATOM   880  C  CA  . TRP A 1 168 ? 157.194 150.567 199.029 1.00 71.66  ? 168 TRP A CA  1 
ATOM   881  C  C   . TRP A 1 168 ? 156.038 149.616 198.771 1.00 71.66  ? 168 TRP A C   1 
ATOM   882  O  O   . TRP A 1 168 ? 155.188 149.895 197.915 1.00 71.66  ? 168 TRP A O   1 
ATOM   883  C  CB  . TRP A 1 168 ? 157.459 151.417 197.786 1.00 71.66  ? 168 TRP A CB  1 
ATOM   884  C  CG  . TRP A 1 168 ? 157.963 150.664 196.597 1.00 71.66  ? 168 TRP A CG  1 
ATOM   885  C  CD1 . TRP A 1 168 ? 157.214 150.071 195.626 1.00 71.66  ? 168 TRP A CD1 1 
ATOM   886  C  CD2 . TRP A 1 168 ? 159.330 150.442 196.239 1.00 71.66  ? 168 TRP A CD2 1 
ATOM   887  N  NE1 . TRP A 1 168 ? 158.028 149.484 194.691 1.00 71.66  ? 168 TRP A NE1 1 
ATOM   888  C  CE2 . TRP A 1 168 ? 159.334 149.698 195.046 1.00 71.66  ? 168 TRP A CE2 1 
ATOM   889  C  CE3 . TRP A 1 168 ? 160.552 150.795 196.816 1.00 71.66  ? 168 TRP A CE3 1 
ATOM   890  C  CZ2 . TRP A 1 168 ? 160.512 149.300 194.419 1.00 71.66  ? 168 TRP A CZ2 1 
ATOM   891  C  CZ3 . TRP A 1 168 ? 161.719 150.400 196.192 1.00 71.66  ? 168 TRP A CZ3 1 
ATOM   892  C  CH2 . TRP A 1 168 ? 161.691 149.662 195.007 1.00 71.66  ? 168 TRP A CH2 1 
ATOM   893  N  N   . ALA A 1 169 ? 155.973 148.499 199.492 1.00 81.43  ? 169 ALA A N   1 
ATOM   894  C  CA  . ALA A 1 169 ? 154.959 147.492 199.224 1.00 81.43  ? 169 ALA A CA  1 
ATOM   895  C  C   . ALA A 1 169 ? 154.158 147.094 200.457 1.00 81.43  ? 169 ALA A C   1 
ATOM   896  O  O   . ALA A 1 169 ? 153.136 146.417 200.315 1.00 81.43  ? 169 ALA A O   1 
ATOM   897  C  CB  . ALA A 1 169 ? 155.601 146.246 198.603 1.00 81.43  ? 169 ALA A CB  1 
ATOM   898  N  N   . THR A 1 170 ? 154.566 147.498 201.655 1.00 91.70  ? 170 THR A N   1 
ATOM   899  C  CA  . THR A 1 170 ? 153.837 147.133 202.859 1.00 91.70  ? 170 THR A CA  1 
ATOM   900  C  C   . THR A 1 170 ? 153.467 148.387 203.640 1.00 91.70  ? 170 THR A C   1 
ATOM   901  O  O   . THR A 1 170 ? 153.986 149.477 203.394 1.00 91.70  ? 170 THR A O   1 
ATOM   902  C  CB  . THR A 1 170 ? 154.646 146.179 203.751 1.00 91.70  ? 170 THR A CB  1 
ATOM   903  O  OG1 . THR A 1 170 ? 155.906 146.775 204.055 1.00 91.70  ? 170 THR A OG1 1 
ATOM   904  C  CG2 . THR A 1 170 ? 154.896 144.860 203.047 1.00 91.70  ? 170 THR A CG2 1 
ATOM   905  N  N   . CYS A 1 171 ? 152.551 148.216 204.588 1.00 97.52  ? 171 CYS A N   1 
ATOM   906  C  CA  . CYS A 1 171 ? 151.975 149.316 205.356 1.00 97.52  ? 171 CYS A CA  1 
ATOM   907  C  C   . CYS A 1 171 ? 152.529 149.359 206.781 1.00 97.52  ? 171 CYS A C   1 
ATOM   908  O  O   . CYS A 1 171 ? 151.797 149.581 207.745 1.00 97.52  ? 171 CYS A O   1 
ATOM   909  C  CB  . CYS A 1 171 ? 150.451 149.209 205.361 1.00 97.52  ? 171 CYS A CB  1 
ATOM   910  S  SG  . CYS A 1 171 ? 149.514 150.654 205.947 1.00 97.52  ? 171 CYS A SG  1 
ATOM   911  N  N   . GLY A 1 172 ? 153.827 149.108 206.945 1.00 97.14  ? 172 GLY A N   1 
ATOM   912  C  CA  . GLY A 1 172 ? 154.454 149.399 208.222 1.00 97.14  ? 172 GLY A CA  1 
ATOM   913  C  C   . GLY A 1 172 ? 155.947 149.651 208.159 1.00 97.14  ? 172 GLY A C   1 
ATOM   914  O  O   . GLY A 1 172 ? 156.707 148.755 207.783 1.00 97.14  ? 172 GLY A O   1 
ATOM   915  N  N   . HIS A 1 173 ? 156.374 150.836 208.591 1.00 91.49  ? 173 HIS A N   1 
ATOM   916  C  CA  . HIS A 1 173 ? 157.768 151.303 208.614 1.00 91.49  ? 173 HIS A CA  1 
ATOM   917  C  C   . HIS A 1 173 ? 157.845 152.505 209.554 1.00 91.49  ? 173 HIS A C   1 
ATOM   918  O  O   . HIS A 1 173 ? 156.879 152.825 210.258 1.00 91.49  ? 173 HIS A O   1 
ATOM   919  C  CB  . HIS A 1 173 ? 158.310 151.664 207.221 1.00 91.49  ? 173 HIS A CB  1 
ATOM   920  C  CG  . HIS A 1 173 ? 158.504 150.496 206.300 1.00 91.49  ? 173 HIS A CG  1 
ATOM   921  N  ND1 . HIS A 1 173 ? 157.516 150.020 205.467 1.00 91.49  ? 173 HIS A ND1 1 
ATOM   922  C  CD2 . HIS A 1 173 ? 159.579 149.696 206.097 1.00 91.49  ? 173 HIS A CD2 1 
ATOM   923  C  CE1 . HIS A 1 173 ? 157.977 148.986 204.783 1.00 91.49  ? 173 HIS A CE1 1 
ATOM   924  N  NE2 . HIS A 1 173 ? 159.227 148.769 205.146 1.00 91.49  ? 173 HIS A NE2 1 
ATOM   925  N  N   . GLU A 1 174 ? 159.005 153.168 209.575 1.00 93.43  ? 174 GLU A N   1 
ATOM   926  C  CA  . GLU A 1 174 ? 159.170 154.364 210.394 1.00 93.43  ? 174 GLU A CA  1 
ATOM   927  C  C   . GLU A 1 174 ? 158.522 155.584 209.749 1.00 93.43  ? 174 GLU A C   1 
ATOM   928  O  O   . GLU A 1 174 ? 158.279 156.585 210.432 1.00 93.43  ? 174 GLU A O   1 
ATOM   929  C  CB  . GLU A 1 174 ? 160.659 154.631 210.650 1.00 93.43  ? 174 GLU A CB  1 
ATOM   930  C  CG  . GLU A 1 174 ? 160.971 155.469 211.898 1.00 93.43  ? 174 GLU A CG  1 
ATOM   931  C  CD  . GLU A 1 174 ? 160.757 154.708 213.199 1.00 93.43  ? 174 GLU A CD  1 
ATOM   932  O  OE1 . GLU A 1 174 ? 161.709 154.049 213.672 1.00 93.43  ? 174 GLU A OE1 1 
ATOM   933  O  OE2 . GLU A 1 174 ? 159.638 154.770 213.748 1.00 93.43  ? 174 GLU A OE2 1 
ATOM   934  N  N   . TRP A 1 175 ? 158.225 155.520 208.448 1.00 83.26  ? 175 TRP A N   1 
ATOM   935  C  CA  . TRP A 1 175 ? 157.679 156.665 207.731 1.00 83.26  ? 175 TRP A CA  1 
ATOM   936  C  C   . TRP A 1 175 ? 156.181 156.575 207.472 1.00 83.26  ? 175 TRP A C   1 
ATOM   937  O  O   . TRP A 1 175 ? 155.564 157.601 207.169 1.00 83.26  ? 175 TRP A O   1 
ATOM   938  C  CB  . TRP A 1 175 ? 158.390 156.844 206.385 1.00 83.26  ? 175 TRP A CB  1 
ATOM   939  C  CG  . TRP A 1 175 ? 158.410 155.616 205.528 1.00 83.26  ? 175 TRP A CG  1 
ATOM   940  C  CD1 . TRP A 1 175 ? 157.425 155.192 204.687 1.00 83.26  ? 175 TRP A CD1 1 
ATOM   941  C  CD2 . TRP A 1 175 ? 159.480 154.675 205.397 1.00 83.26  ? 175 TRP A CD2 1 
ATOM   942  N  NE1 . TRP A 1 175 ? 157.805 154.036 204.055 1.00 83.26  ? 175 TRP A NE1 1 
ATOM   943  C  CE2 . TRP A 1 175 ? 159.066 153.699 204.471 1.00 83.26  ? 175 TRP A CE2 1 
ATOM   944  C  CE3 . TRP A 1 175 ? 160.743 154.557 205.978 1.00 83.26  ? 175 TRP A CE3 1 
ATOM   945  C  CZ2 . TRP A 1 175 ? 159.870 152.622 204.113 1.00 83.26  ? 175 TRP A CZ2 1 
ATOM   946  C  CZ3 . TRP A 1 175 ? 161.539 153.488 205.621 1.00 83.26  ? 175 TRP A CZ3 1 
ATOM   947  C  CH2 . TRP A 1 175 ? 161.099 152.534 204.699 1.00 83.26  ? 175 TRP A CH2 1 
ATOM   948  N  N   . ASN A 1 176 ? 155.588 155.388 207.568 1.00 92.90  ? 176 ASN A N   1 
ATOM   949  C  CA  . ASN A 1 176 ? 154.173 155.228 207.259 1.00 92.90  ? 176 ASN A CA  1 
ATOM   950  C  C   . ASN A 1 176 ? 153.310 155.875 208.335 1.00 92.90  ? 176 ASN A C   1 
ATOM   951  O  O   . ASN A 1 176 ? 153.614 155.788 209.528 1.00 92.90  ? 176 ASN A O   1 
ATOM   952  C  CB  . ASN A 1 176 ? 153.830 153.747 207.124 1.00 92.90  ? 176 ASN A CB  1 
ATOM   953  C  CG  . ASN A 1 176 ? 154.274 153.170 205.799 1.00 92.90  ? 176 ASN A CG  1 
ATOM   954  O  OD1 . ASN A 1 176 ? 154.543 153.903 204.849 1.00 92.90  ? 176 ASN A OD1 1 
ATOM   955  N  ND2 . ASN A 1 176 ? 154.370 151.850 205.733 1.00 92.90  ? 176 ASN A ND2 1 
ATOM   956  N  N   . THR A 1 177 ? 152.231 156.524 207.910 1.00 99.70  ? 177 THR A N   1 
ATOM   957  C  CA  . THR A 1 177 ? 151.339 157.222 208.821 1.00 99.70  ? 177 THR A CA  1 
ATOM   958  C  C   . THR A 1 177 ? 150.190 156.302 209.232 1.00 99.70  ? 177 THR A C   1 
ATOM   959  O  O   . THR A 1 177 ? 150.126 155.134 208.841 1.00 99.70  ? 177 THR A O   1 
ATOM   960  C  CB  . THR A 1 177 ? 150.832 158.510 208.177 1.00 99.70  ? 177 THR A CB  1 
ATOM   961  O  OG1 . THR A 1 177 ? 150.040 158.190 207.027 1.00 99.70  ? 177 THR A OG1 1 
ATOM   962  C  CG2 . THR A 1 177 ? 151.999 159.383 207.750 1.00 99.70  ? 177 THR A CG2 1 
ATOM   963  N  N   . GLU A 1 178 ? 149.265 156.829 210.038 1.00 109.53 ? 178 GLU A N   1 
ATOM   964  C  CA  . GLU A 1 178 ? 148.133 156.038 210.506 1.00 109.53 ? 178 GLU A CA  1 
ATOM   965  C  C   . GLU A 1 178 ? 147.115 155.784 209.405 1.00 109.53 ? 178 GLU A C   1 
ATOM   966  O  O   . GLU A 1 178 ? 146.470 154.729 209.392 1.00 109.53 ? 178 GLU A O   1 
ATOM   967  C  CB  . GLU A 1 178 ? 147.462 156.738 211.690 1.00 109.53 ? 178 GLU A CB  1 
ATOM   968  C  CG  . GLU A 1 178 ? 146.450 155.886 212.446 1.00 109.53 ? 178 GLU A CG  1 
ATOM   969  C  CD  . GLU A 1 178 ? 147.103 154.867 213.361 1.00 109.53 ? 178 GLU A CD  1 
ATOM   970  O  OE1 . GLU A 1 178 ? 147.508 153.792 212.869 1.00 109.53 ? 178 GLU A OE1 1 
ATOM   971  O  OE2 . GLU A 1 178 ? 147.214 155.143 214.573 1.00 109.53 ? 178 GLU A OE2 1 
ATOM   972  N  N   . ASN A 1 179 ? 146.968 156.718 208.468 1.00 108.13 ? 179 ASN A N   1 
ATOM   973  C  CA  . ASN A 1 179 ? 145.957 156.608 207.425 1.00 108.13 ? 179 ASN A CA  1 
ATOM   974  C  C   . ASN A 1 179 ? 146.370 155.711 206.262 1.00 108.13 ? 179 ASN A C   1 
ATOM   975  O  O   . ASN A 1 179 ? 145.645 155.652 205.264 1.00 108.13 ? 179 ASN A O   1 
ATOM   976  C  CB  . ASN A 1 179 ? 145.572 158.009 206.928 1.00 108.13 ? 179 ASN A CB  1 
ATOM   977  C  CG  . ASN A 1 179 ? 146.752 158.793 206.361 1.00 108.13 ? 179 ASN A CG  1 
ATOM   978  O  OD1 . ASN A 1 179 ? 147.861 158.282 206.224 1.00 108.13 ? 179 ASN A OD1 1 
ATOM   979  N  ND2 . ASN A 1 179 ? 146.507 160.057 206.036 1.00 108.13 ? 179 ASN A ND2 1 
ATOM   980  N  N   . CYS A 1 180 ? 147.504 155.024 206.360 1.00 105.28 ? 180 CYS A N   1 
ATOM   981  C  CA  . CYS A 1 180 ? 147.892 154.061 205.341 1.00 105.28 ? 180 CYS A CA  1 
ATOM   982  C  C   . CYS A 1 180 ? 146.982 152.837 205.375 1.00 105.28 ? 180 CYS A C   1 
ATOM   983  O  O   . CYS A 1 180 ? 146.295 152.560 206.363 1.00 105.28 ? 180 CYS A O   1 
ATOM   984  C  CB  . CYS A 1 180 ? 149.345 153.632 205.540 1.00 105.28 ? 180 CYS A CB  1 
ATOM   985  S  SG  . CYS A 1 180 ? 149.847 152.155 204.617 1.00 105.28 ? 180 CYS A SG  1 
ATOM   986  N  N   . VAL A 1 181 ? 146.992 152.093 204.271 1.00 103.85 ? 181 VAL A N   1 
ATOM   987  C  CA  . VAL A 1 181 ? 146.316 150.805 204.193 1.00 103.85 ? 181 VAL A CA  1 
ATOM   988  C  C   . VAL A 1 181 ? 147.059 149.963 203.163 1.00 103.85 ? 181 VAL A C   1 
ATOM   989  O  O   . VAL A 1 181 ? 147.706 150.491 202.255 1.00 103.85 ? 181 VAL A O   1 
ATOM   990  C  CB  . VAL A 1 181 ? 144.811 150.968 203.862 1.00 103.85 ? 181 VAL A CB  1 
ATOM   991  C  CG1 . VAL A 1 181 ? 144.613 151.403 202.430 1.00 103.85 ? 181 VAL A CG1 1 
ATOM   992  C  CG2 . VAL A 1 181 ? 144.025 149.697 204.182 1.00 103.85 ? 181 VAL A CG2 1 
ATOM   993  N  N   . GLU A 1 182 ? 147.010 148.641 203.350 1.00 106.18 ? 182 GLU A N   1 
ATOM   994  C  CA  . GLU A 1 182 ? 147.758 147.724 202.495 1.00 106.18 ? 182 GLU A CA  1 
ATOM   995  C  C   . GLU A 1 182 ? 147.248 147.737 201.059 1.00 106.18 ? 182 GLU A C   1 
ATOM   996  O  O   . GLU A 1 182 ? 148.043 147.660 200.115 1.00 106.18 ? 182 GLU A O   1 
ATOM   997  C  CB  . GLU A 1 182 ? 147.686 146.309 203.073 1.00 106.18 ? 182 GLU A CB  1 
ATOM   998  C  CG  . GLU A 1 182 ? 148.666 145.289 202.486 1.00 106.18 ? 182 GLU A CG  1 
ATOM   999  C  CD  . GLU A 1 182 ? 150.125 145.719 202.509 1.00 106.18 ? 182 GLU A CD  1 
ATOM   1000 O  OE1 . GLU A 1 182 ? 150.539 146.470 203.419 1.00 106.18 ? 182 GLU A OE1 1 
ATOM   1001 O  OE2 . GLU A 1 182 ? 150.869 145.286 201.606 1.00 106.18 ? 182 GLU A OE2 1 
ATOM   1002 N  N   . PHE A 1 183 ? 145.924 147.797 200.880 1.00 107.27 ? 183 PHE A N   1 
ATOM   1003 C  CA  . PHE A 1 183 ? 145.211 147.713 199.604 1.00 107.27 ? 183 PHE A CA  1 
ATOM   1004 C  C   . PHE A 1 183 ? 145.436 146.394 198.870 1.00 107.27 ? 183 PHE A C   1 
ATOM   1005 O  O   . PHE A 1 183 ? 145.065 146.273 197.698 1.00 107.27 ? 183 PHE A O   1 
ATOM   1006 C  CB  . PHE A 1 183 ? 145.551 148.883 198.668 1.00 107.27 ? 183 PHE A CB  1 
ATOM   1007 C  CG  . PHE A 1 183 ? 144.721 150.108 198.899 1.00 107.27 ? 183 PHE A CG  1 
ATOM   1008 C  CD1 . PHE A 1 183 ? 143.373 150.000 199.191 1.00 107.27 ? 183 PHE A CD1 1 
ATOM   1009 C  CD2 . PHE A 1 183 ? 145.285 151.368 198.807 1.00 107.27 ? 183 PHE A CD2 1 
ATOM   1010 C  CE1 . PHE A 1 183 ? 142.602 151.129 199.397 1.00 107.27 ? 183 PHE A CE1 1 
ATOM   1011 C  CE2 . PHE A 1 183 ? 144.523 152.500 199.013 1.00 107.27 ? 183 PHE A CE2 1 
ATOM   1012 C  CZ  . PHE A 1 183 ? 143.178 152.381 199.305 1.00 107.27 ? 183 PHE A CZ  1 
ATOM   1013 N  N   . GLN A 1 184 ? 146.029 145.398 199.526 1.00 111.74 ? 184 GLN A N   1 
ATOM   1014 C  CA  . GLN A 1 184 ? 146.253 144.089 198.929 1.00 111.74 ? 184 GLN A CA  1 
ATOM   1015 C  C   . GLN A 1 184 ? 145.923 142.930 199.853 1.00 111.74 ? 184 GLN A C   1 
ATOM   1016 O  O   . GLN A 1 184 ? 145.847 141.792 199.373 1.00 111.74 ? 184 GLN A O   1 
ATOM   1017 C  CB  . GLN A 1 184 ? 147.713 143.944 198.470 1.00 111.74 ? 184 GLN A CB  1 
ATOM   1018 C  CG  . GLN A 1 184 ? 148.094 144.807 197.279 1.00 111.74 ? 184 GLN A CG  1 
ATOM   1019 C  CD  . GLN A 1 184 ? 147.418 144.361 196.001 1.00 111.74 ? 184 GLN A CD  1 
ATOM   1020 O  OE1 . GLN A 1 184 ? 146.555 145.056 195.467 1.00 111.74 ? 184 GLN A OE1 1 
ATOM   1021 N  NE2 . GLN A 1 184 ? 147.806 143.194 195.503 1.00 111.74 ? 184 GLN A NE2 1 
ATOM   1022 N  N   . LYS A 1 185 ? 145.730 143.169 201.152 1.00 128.94 ? 185 LYS A N   1 
ATOM   1023 C  CA  . LYS A 1 185 ? 145.468 142.079 202.084 1.00 128.94 ? 185 LYS A CA  1 
ATOM   1024 C  C   . LYS A 1 185 ? 144.066 141.505 201.930 1.00 128.94 ? 185 LYS A C   1 
ATOM   1025 O  O   . LYS A 1 185 ? 143.833 140.361 202.335 1.00 128.94 ? 185 LYS A O   1 
ATOM   1026 C  CB  . LYS A 1 185 ? 145.682 142.551 203.523 1.00 128.94 ? 185 LYS A CB  1 
ATOM   1027 C  CG  . LYS A 1 185 ? 144.733 143.649 203.971 1.00 128.94 ? 185 LYS A CG  1 
ATOM   1028 C  CD  . LYS A 1 185 ? 144.760 143.814 205.481 1.00 128.94 ? 185 LYS A CD  1 
ATOM   1029 C  CE  . LYS A 1 185 ? 146.054 144.457 205.945 1.00 128.94 ? 185 LYS A CE  1 
ATOM   1030 N  NZ  . LYS A 1 185 ? 146.029 144.766 207.401 1.00 128.94 ? 185 LYS A NZ  1 
ATOM   1031 N  N   . LEU A 1 186 ? 143.135 142.262 201.358 1.00 139.34 ? 186 LEU A N   1 
ATOM   1032 C  CA  . LEU A 1 186 ? 141.783 141.771 201.147 1.00 139.34 ? 186 LEU A CA  1 
ATOM   1033 C  C   . LEU A 1 186 ? 141.239 142.357 199.854 1.00 139.34 ? 186 LEU A C   1 
ATOM   1034 O  O   . LEU A 1 186 ? 141.665 143.425 199.404 1.00 139.34 ? 186 LEU A O   1 
ATOM   1035 C  CB  . LEU A 1 186 ? 140.865 142.116 202.325 1.00 139.34 ? 186 LEU A CB  1 
ATOM   1036 C  CG  . LEU A 1 186 ? 140.769 141.098 203.462 1.00 139.34 ? 186 LEU A CG  1 
ATOM   1037 C  CD1 . LEU A 1 186 ? 139.676 141.494 204.441 1.00 139.34 ? 186 LEU A CD1 1 
ATOM   1038 C  CD2 . LEU A 1 186 ? 140.516 139.703 202.912 1.00 139.34 ? 186 LEU A CD2 1 
ATOM   1039 N  N   . ASN A 1 187 ? 140.285 141.640 199.261 1.00 148.39 ? 187 ASN A N   1 
ATOM   1040 C  CA  . ASN A 1 187 ? 139.673 142.089 198.015 1.00 148.39 ? 187 ASN A CA  1 
ATOM   1041 C  C   . ASN A 1 187 ? 138.705 143.241 198.263 1.00 148.39 ? 187 ASN A C   1 
ATOM   1042 O  O   . ASN A 1 187 ? 138.859 144.330 197.700 1.00 148.39 ? 187 ASN A O   1 
ATOM   1043 C  CB  . ASN A 1 187 ? 138.960 140.918 197.331 1.00 148.39 ? 187 ASN A CB  1 
ATOM   1044 C  CG  . ASN A 1 187 ? 138.860 141.094 195.829 1.00 148.39 ? 187 ASN A CG  1 
ATOM   1045 O  OD1 . ASN A 1 187 ? 139.421 142.033 195.264 1.00 148.39 ? 187 ASN A OD1 1 
ATOM   1046 N  ND2 . ASN A 1 187 ? 138.146 140.187 195.173 1.00 148.39 ? 187 ASN A ND2 1 
ATOM   1047 N  N   . VAL A 1 188 ? 137.699 143.016 199.110 1.00 149.19 ? 188 VAL A N   1 
ATOM   1048 C  CA  . VAL A 1 188 ? 136.765 144.087 199.436 1.00 149.19 ? 188 VAL A CA  1 
ATOM   1049 C  C   . VAL A 1 188 ? 137.346 145.022 200.493 1.00 149.19 ? 188 VAL A C   1 
ATOM   1050 O  O   . VAL A 1 188 ? 137.001 146.210 200.521 1.00 149.19 ? 188 VAL A O   1 
ATOM   1051 C  CB  . VAL A 1 188 ? 135.411 143.502 199.876 1.00 149.19 ? 188 VAL A CB  1 
ATOM   1052 C  CG1 . VAL A 1 188 ? 134.719 142.838 198.698 1.00 149.19 ? 188 VAL A CG1 1 
ATOM   1053 C  CG2 . VAL A 1 188 ? 135.595 142.503 201.009 1.00 149.19 ? 188 VAL A CG2 1 
ATOM   1054 N  N   . SER A 1 189 ? 138.229 144.506 201.359 1.00 148.47 ? 189 SER A N   1 
ATOM   1055 C  CA  . SER A 1 189 ? 138.932 145.253 202.403 1.00 148.47 ? 189 SER A CA  1 
ATOM   1056 C  C   . SER A 1 189 ? 137.989 146.032 203.314 1.00 148.47 ? 189 SER A C   1 
ATOM   1057 O  O   . SER A 1 189 ? 136.894 145.559 203.636 1.00 148.47 ? 189 SER A O   1 
ATOM   1058 C  CB  . SER A 1 189 ? 139.965 146.196 201.778 1.00 148.47 ? 189 SER A CB  1 
ATOM   1059 O  OG  . SER A 1 189 ? 140.933 145.472 201.039 1.00 148.47 ? 189 SER A OG  1 
ATOM   1060 N  N   . ASN A 1 190 ? 138.410 147.227 203.736 1.00 151.51 ? 190 ASN A N   1 
ATOM   1061 C  CA  . ASN A 1 190 ? 137.583 148.083 204.577 1.00 151.51 ? 190 ASN A CA  1 
ATOM   1062 C  C   . ASN A 1 190 ? 137.682 149.545 204.156 1.00 151.51 ? 190 ASN A C   1 
ATOM   1063 O  O   . ASN A 1 190 ? 137.609 150.443 205.002 1.00 151.51 ? 190 ASN A O   1 
ATOM   1064 C  CB  . ASN A 1 190 ? 137.961 147.938 206.054 1.00 151.51 ? 190 ASN A CB  1 
ATOM   1065 C  CG  . ASN A 1 190 ? 139.459 147.978 206.281 1.00 151.51 ? 190 ASN A CG  1 
ATOM   1066 O  OD1 . ASN A 1 190 ? 140.242 147.983 205.332 1.00 151.51 ? 190 ASN A OD1 1 
ATOM   1067 N  ND2 . ASN A 1 190 ? 139.865 148.007 207.544 1.00 151.51 ? 190 ASN A ND2 1 
ATOM   1068 N  N   . TYR A 1 191 ? 137.848 149.805 202.858 1.00 147.36 ? 191 TYR A N   1 
ATOM   1069 C  CA  . TYR A 1 191 ? 137.949 151.177 202.371 1.00 147.36 ? 191 TYR A CA  1 
ATOM   1070 C  C   . TYR A 1 191 ? 136.571 151.800 202.178 1.00 147.36 ? 191 TYR A C   1 
ATOM   1071 O  O   . TYR A 1 191 ? 135.577 151.294 202.712 1.00 147.36 ? 191 TYR A O   1 
ATOM   1072 C  CB  . TYR A 1 191 ? 138.762 151.250 201.071 1.00 147.36 ? 191 TYR A CB  1 
ATOM   1073 C  CG  . TYR A 1 191 ? 138.372 150.265 199.988 1.00 147.36 ? 191 TYR A CG  1 
ATOM   1074 C  CD1 . TYR A 1 191 ? 137.282 150.503 199.158 1.00 147.36 ? 191 TYR A CD1 1 
ATOM   1075 C  CD2 . TYR A 1 191 ? 139.119 149.114 199.771 1.00 147.36 ? 191 TYR A CD2 1 
ATOM   1076 C  CE1 . TYR A 1 191 ? 136.932 149.611 198.161 1.00 147.36 ? 191 TYR A CE1 1 
ATOM   1077 C  CE2 . TYR A 1 191 ? 138.779 148.218 198.773 1.00 147.36 ? 191 TYR A CE2 1 
ATOM   1078 C  CZ  . TYR A 1 191 ? 137.685 148.472 197.973 1.00 147.36 ? 191 TYR A CZ  1 
ATOM   1079 O  OH  . TYR A 1 191 ? 137.342 147.583 196.981 1.00 147.36 ? 191 TYR A OH  1 
ATOM   1080 N  N   . SER A 1 192 ? 136.531 152.927 201.458 1.00 146.04 ? 192 SER A N   1 
ATOM   1081 C  CA  . SER A 1 192 ? 135.385 153.787 201.141 1.00 146.04 ? 192 SER A CA  1 
ATOM   1082 C  C   . SER A 1 192 ? 134.910 154.604 202.337 1.00 146.04 ? 192 SER A C   1 
ATOM   1083 O  O   . SER A 1 192 ? 134.011 155.439 202.180 1.00 146.04 ? 192 SER A O   1 
ATOM   1084 C  CB  . SER A 1 192 ? 134.191 153.021 200.547 1.00 146.04 ? 192 SER A CB  1 
ATOM   1085 O  OG  . SER A 1 192 ? 134.544 152.390 199.328 1.00 146.04 ? 192 SER A OG  1 
ATOM   1086 N  N   . HIS A 1 193 ? 135.478 154.397 203.524 1.00 143.15 ? 193 HIS A N   1 
ATOM   1087 C  CA  . HIS A 1 193 ? 135.307 155.319 204.638 1.00 143.15 ? 193 HIS A CA  1 
ATOM   1088 C  C   . HIS A 1 193 ? 136.692 155.721 205.128 1.00 143.15 ? 193 HIS A C   1 
ATOM   1089 O  O   . HIS A 1 193 ? 136.908 156.857 205.562 1.00 143.15 ? 193 HIS A O   1 
ATOM   1090 C  CB  . HIS A 1 193 ? 134.457 154.692 205.749 1.00 143.15 ? 193 HIS A CB  1 
ATOM   1091 C  CG  . HIS A 1 193 ? 135.163 153.635 206.539 1.00 143.15 ? 193 HIS A CG  1 
ATOM   1092 N  ND1 . HIS A 1 193 ? 135.792 153.896 207.737 1.00 143.15 ? 193 HIS A ND1 1 
ATOM   1093 C  CD2 . HIS A 1 193 ? 135.335 152.312 206.304 1.00 143.15 ? 193 HIS A CD2 1 
ATOM   1094 C  CE1 . HIS A 1 193 ? 136.322 152.781 208.206 1.00 143.15 ? 193 HIS A CE1 1 
ATOM   1095 N  NE2 . HIS A 1 193 ? 136.060 151.805 207.355 1.00 143.15 ? 193 HIS A NE2 1 
ATOM   1096 N  N   . VAL A 1 194 ? 137.646 154.792 205.031 1.00 135.96 ? 194 VAL A N   1 
ATOM   1097 C  CA  . VAL A 1 194 ? 139.050 155.146 205.198 1.00 135.96 ? 194 VAL A CA  1 
ATOM   1098 C  C   . VAL A 1 194 ? 139.494 156.031 204.038 1.00 135.96 ? 194 VAL A C   1 
ATOM   1099 O  O   . VAL A 1 194 ? 140.337 156.921 204.208 1.00 135.96 ? 194 VAL A O   1 
ATOM   1100 C  CB  . VAL A 1 194 ? 139.901 153.865 205.325 1.00 135.96 ? 194 VAL A CB  1 
ATOM   1101 C  CG1 . VAL A 1 194 ? 141.379 154.188 205.510 1.00 135.96 ? 194 VAL A CG1 1 
ATOM   1102 C  CG2 . VAL A 1 194 ? 139.398 153.005 206.472 1.00 135.96 ? 194 VAL A CG2 1 
ATOM   1103 N  N   . SER A 1 195 ? 138.927 155.811 202.847 1.00 134.64 ? 195 SER A N   1 
ATOM   1104 C  CA  . SER A 1 195 ? 139.161 156.713 201.723 1.00 134.64 ? 195 SER A CA  1 
ATOM   1105 C  C   . SER A 1 195 ? 138.604 158.102 202.008 1.00 134.64 ? 195 SER A C   1 
ATOM   1106 O  O   . SER A 1 195 ? 139.210 159.112 201.630 1.00 134.64 ? 195 SER A O   1 
ATOM   1107 C  CB  . SER A 1 195 ? 138.541 156.137 200.450 1.00 134.64 ? 195 SER A CB  1 
ATOM   1108 O  OG  . SER A 1 195 ? 138.995 154.815 200.215 1.00 134.64 ? 195 SER A OG  1 
ATOM   1109 N  N   . LEU A 1 196 ? 137.441 158.172 202.664 1.00 137.75 ? 196 LEU A N   1 
ATOM   1110 C  CA  . LEU A 1 196 ? 136.919 159.455 203.124 1.00 137.75 ? 196 LEU A CA  1 
ATOM   1111 C  C   . LEU A 1 196 ? 137.813 160.063 204.198 1.00 137.75 ? 196 LEU A C   1 
ATOM   1112 O  O   . LEU A 1 196 ? 137.886 161.291 204.321 1.00 137.75 ? 196 LEU A O   1 
ATOM   1113 C  CB  . LEU A 1 196 ? 135.489 159.282 203.642 1.00 137.75 ? 196 LEU A CB  1 
ATOM   1114 C  CG  . LEU A 1 196 ? 134.636 160.533 203.867 1.00 137.75 ? 196 LEU A CG  1 
ATOM   1115 C  CD1 . LEU A 1 196 ? 133.214 160.288 203.393 1.00 137.75 ? 196 LEU A CD1 1 
ATOM   1116 C  CD2 . LEU A 1 196 ? 134.635 160.944 205.334 1.00 137.75 ? 196 LEU A CD2 1 
ATOM   1117 N  N   . GLN A 1 197 ? 138.498 159.223 204.977 1.00 132.00 ? 197 GLN A N   1 
ATOM   1118 C  CA  . GLN A 1 197 ? 139.513 159.668 205.924 1.00 132.00 ? 197 GLN A CA  1 
ATOM   1119 C  C   . GLN A 1 197 ? 140.898 159.756 205.293 1.00 132.00 ? 197 GLN A C   1 
ATOM   1120 O  O   . GLN A 1 197 ? 141.906 159.632 206.005 1.00 132.00 ? 197 GLN A O   1 
ATOM   1121 C  CB  . GLN A 1 197 ? 139.539 158.743 207.142 1.00 132.00 ? 197 GLN A CB  1 
ATOM   1122 C  CG  . GLN A 1 197 ? 138.403 158.976 208.126 1.00 132.00 ? 197 GLN A CG  1 
ATOM   1123 C  CD  . GLN A 1 197 ? 138.181 160.446 208.421 1.00 132.00 ? 197 GLN A CD  1 
ATOM   1124 O  OE1 . GLN A 1 197 ? 137.148 161.012 208.067 1.00 132.00 ? 197 GLN A OE1 1 
ATOM   1125 N  NE2 . GLN A 1 197 ? 139.154 161.072 209.074 1.00 132.00 ? 197 GLN A NE2 1 
ATOM   1126 N  N   . ASN A 1 198 ? 140.959 159.948 203.970 1.00 123.46 ? 198 ASN A N   1 
ATOM   1127 C  CA  . ASN A 1 198 ? 142.193 160.113 203.197 1.00 123.46 ? 198 ASN A CA  1 
ATOM   1128 C  C   . ASN A 1 198 ? 143.106 158.888 203.315 1.00 123.46 ? 198 ASN A C   1 
ATOM   1129 O  O   . ASN A 1 198 ? 144.210 158.946 203.859 1.00 123.46 ? 198 ASN A O   1 
ATOM   1130 C  CB  . ASN A 1 198 ? 142.930 161.398 203.596 1.00 123.46 ? 198 ASN A CB  1 
ATOM   1131 C  CG  . ASN A 1 198 ? 141.986 162.565 203.821 1.00 123.46 ? 198 ASN A CG  1 
ATOM   1132 O  OD1 . ASN A 1 198 ? 141.036 162.764 203.064 1.00 123.46 ? 198 ASN A OD1 1 
ATOM   1133 N  ND2 . ASN A 1 198 ? 142.243 163.340 204.868 1.00 123.46 ? 198 ASN A ND2 1 
ATOM   1134 N  N   . ALA A 1 199 ? 142.613 157.765 202.796 1.00 111.07 ? 199 ALA A N   1 
ATOM   1135 C  CA  . ALA A 1 199 ? 143.446 156.580 202.650 1.00 111.07 ? 199 ALA A CA  1 
ATOM   1136 C  C   . ALA A 1 199 ? 144.534 156.827 201.615 1.00 111.07 ? 199 ALA A C   1 
ATOM   1137 O  O   . ALA A 1 199 ? 144.344 157.584 200.660 1.00 111.07 ? 199 ALA A O   1 
ATOM   1138 C  CB  . ALA A 1 199 ? 142.602 155.377 202.239 1.00 111.07 ? 199 ALA A CB  1 
ATOM   1139 N  N   . THR A 1 200 ? 145.683 156.186 201.807 1.00 97.85  ? 200 THR A N   1 
ATOM   1140 C  CA  . THR A 1 200 ? 146.832 156.389 200.939 1.00 97.85  ? 200 THR A CA  1 
ATOM   1141 C  C   . THR A 1 200 ? 147.485 155.053 200.619 1.00 97.85  ? 200 THR A C   1 
ATOM   1142 O  O   . THR A 1 200 ? 147.649 154.205 201.501 1.00 97.85  ? 200 THR A O   1 
ATOM   1143 C  CB  . THR A 1 200 ? 147.853 157.330 201.591 1.00 97.85  ? 200 THR A CB  1 
ATOM   1144 O  OG1 . THR A 1 200 ? 147.165 158.423 202.211 1.00 97.85  ? 200 THR A OG1 1 
ATOM   1145 C  CG2 . THR A 1 200 ? 148.795 157.889 200.549 1.00 97.85  ? 200 THR A CG2 1 
ATOM   1146 N  N   . SER A 1 201 ? 147.846 154.869 199.351 1.00 88.44  ? 201 SER A N   1 
ATOM   1147 C  CA  . SER A 1 201 ? 148.573 153.681 198.942 1.00 88.44  ? 201 SER A CA  1 
ATOM   1148 C  C   . SER A 1 201 ? 149.992 153.715 199.511 1.00 88.44  ? 201 SER A C   1 
ATOM   1149 O  O   . SER A 1 201 ? 150.548 154.793 199.733 1.00 88.44  ? 201 SER A O   1 
ATOM   1150 C  CB  . SER A 1 201 ? 148.609 153.580 197.418 1.00 88.44  ? 201 SER A CB  1 
ATOM   1151 O  OG  . SER A 1 201 ? 149.308 154.669 196.846 1.00 88.44  ? 201 SER A OG  1 
ATOM   1152 N  N   . PRO A 1 202 ? 150.583 152.546 199.792 1.00 80.93  ? 202 PRO A N   1 
ATOM   1153 C  CA  . PRO A 1 202 ? 151.910 152.525 200.436 1.00 80.93  ? 202 PRO A CA  1 
ATOM   1154 C  C   . PRO A 1 202 ? 153.022 153.164 199.624 1.00 80.93  ? 202 PRO A C   1 
ATOM   1155 O  O   . PRO A 1 202 ? 153.940 153.740 200.217 1.00 80.93  ? 202 PRO A O   1 
ATOM   1156 C  CB  . PRO A 1 202 ? 152.167 151.028 200.646 1.00 80.93  ? 202 PRO A CB  1 
ATOM   1157 C  CG  . PRO A 1 202 ? 150.816 150.420 200.693 1.00 80.93  ? 202 PRO A CG  1 
ATOM   1158 C  CD  . PRO A 1 202 ? 149.996 151.197 199.717 1.00 80.93  ? 202 PRO A CD  1 
ATOM   1159 N  N   . VAL A 1 203 ? 152.981 153.077 198.292 1.00 71.86  ? 203 VAL A N   1 
ATOM   1160 C  CA  . VAL A 1 203 ? 154.005 153.734 197.483 1.00 71.86  ? 203 VAL A CA  1 
ATOM   1161 C  C   . VAL A 1 203 ? 153.866 155.252 197.560 1.00 71.86  ? 203 VAL A C   1 
ATOM   1162 O  O   . VAL A 1 203 ? 154.872 155.977 197.612 1.00 71.86  ? 203 VAL A O   1 
ATOM   1163 C  CB  . VAL A 1 203 ? 153.958 153.200 196.034 1.00 71.86  ? 203 VAL A CB  1 
ATOM   1164 C  CG1 . VAL A 1 203 ? 152.570 153.336 195.431 1.00 71.86  ? 203 VAL A CG1 1 
ATOM   1165 C  CG2 . VAL A 1 203 ? 154.982 153.904 195.164 1.00 71.86  ? 203 VAL A CG2 1 
ATOM   1166 N  N   . MET A 1 204 ? 152.626 155.749 197.614 1.00 77.62  ? 204 MET A N   1 
ATOM   1167 C  CA  . MET A 1 204 ? 152.373 157.182 197.701 1.00 77.62  ? 204 MET A CA  1 
ATOM   1168 C  C   . MET A 1 204 ? 152.893 157.750 199.013 1.00 77.62  ? 204 MET A C   1 
ATOM   1169 O  O   . MET A 1 204 ? 153.403 158.875 199.052 1.00 77.62  ? 204 MET A O   1 
ATOM   1170 C  CB  . MET A 1 204 ? 150.875 157.443 197.559 1.00 77.62  ? 204 MET A CB  1 
ATOM   1171 C  CG  . MET A 1 204 ? 150.504 158.850 197.174 1.00 77.62  ? 204 MET A CG  1 
ATOM   1172 S  SD  . MET A 1 204 ? 151.429 159.399 195.740 1.00 77.62  ? 204 MET A SD  1 
ATOM   1173 C  CE  . MET A 1 204 ? 152.200 160.867 196.399 1.00 77.62  ? 204 MET A CE  1 
ATOM   1174 N  N   . GLU A 1 205 ? 152.773 156.985 200.099 1.00 84.32  ? 205 GLU A N   1 
ATOM   1175 C  CA  . GLU A 1 205 ? 153.350 157.414 201.366 1.00 84.32  ? 205 GLU A CA  1 
ATOM   1176 C  C   . GLU A 1 205 ? 154.862 157.261 201.370 1.00 84.32  ? 205 GLU A C   1 
ATOM   1177 O  O   . GLU A 1 205 ? 155.567 158.114 201.922 1.00 84.32  ? 205 GLU A O   1 
ATOM   1178 C  CB  . GLU A 1 205 ? 152.749 156.627 202.526 1.00 84.32  ? 205 GLU A CB  1 
ATOM   1179 C  CG  . GLU A 1 205 ? 151.418 157.141 203.014 1.00 84.32  ? 205 GLU A CG  1 
ATOM   1180 C  CD  . GLU A 1 205 ? 151.026 156.522 204.334 1.00 84.32  ? 205 GLU A CD  1 
ATOM   1181 O  OE1 . GLU A 1 205 ? 151.783 155.663 204.831 1.00 84.32  ? 205 GLU A OE1 1 
ATOM   1182 O  OE2 . GLU A 1 205 ? 149.962 156.887 204.872 1.00 84.32  ? 205 GLU A OE2 1 
ATOM   1183 N  N   . PHE A 1 206 ? 155.376 156.172 200.785 1.00 71.88  ? 206 PHE A N   1 
ATOM   1184 C  CA  . PHE A 1 206 ? 156.811 155.902 200.839 1.00 71.88  ? 206 PHE A CA  1 
ATOM   1185 C  C   . PHE A 1 206 ? 157.598 156.977 200.116 1.00 71.88  ? 206 PHE A C   1 
ATOM   1186 O  O   . PHE A 1 206 ? 158.599 157.474 200.639 1.00 71.88  ? 206 PHE A O   1 
ATOM   1187 C  CB  . PHE A 1 206 ? 157.140 154.538 200.236 1.00 71.88  ? 206 PHE A CB  1 
ATOM   1188 C  CG  . PHE A 1 206 ? 158.613 154.339 199.971 1.00 71.88  ? 206 PHE A CG  1 
ATOM   1189 C  CD1 . PHE A 1 206 ? 159.490 154.116 201.017 1.00 71.88  ? 206 PHE A CD1 1 
ATOM   1190 C  CD2 . PHE A 1 206 ? 159.123 154.388 198.684 1.00 71.88  ? 206 PHE A CD2 1 
ATOM   1191 C  CE1 . PHE A 1 206 ? 160.841 153.937 200.786 1.00 71.88  ? 206 PHE A CE1 1 
ATOM   1192 C  CE2 . PHE A 1 206 ? 160.472 154.209 198.452 1.00 71.88  ? 206 PHE A CE2 1 
ATOM   1193 C  CZ  . PHE A 1 206 ? 161.331 153.986 199.503 1.00 71.88  ? 206 PHE A CZ  1 
ATOM   1194 N  N   . TRP A 1 207 ? 157.143 157.361 198.921 1.00 67.17  ? 207 TRP A N   1 
ATOM   1195 C  CA  . TRP A 1 207 ? 157.836 158.386 198.146 1.00 67.17  ? 207 TRP A CA  1 
ATOM   1196 C  C   . TRP A 1 207 ? 157.900 159.704 198.912 1.00 67.17  ? 207 TRP A C   1 
ATOM   1197 O  O   . TRP A 1 207 ? 158.994 160.212 199.195 1.00 67.17  ? 207 TRP A O   1 
ATOM   1198 C  CB  . TRP A 1 207 ? 157.130 158.555 196.800 1.00 67.17  ? 207 TRP A CB  1 
ATOM   1199 C  CG  . TRP A 1 207 ? 157.269 159.890 196.155 1.00 67.17  ? 207 TRP A CG  1 
ATOM   1200 C  CD1 . TRP A 1 207 ? 156.371 160.911 196.194 1.00 67.17  ? 207 TRP A CD1 1 
ATOM   1201 C  CD2 . TRP A 1 207 ? 158.343 160.332 195.320 1.00 67.17  ? 207 TRP A CD2 1 
ATOM   1202 N  NE1 . TRP A 1 207 ? 156.831 161.974 195.460 1.00 67.17  ? 207 TRP A NE1 1 
ATOM   1203 C  CE2 . TRP A 1 207 ? 158.040 161.642 194.911 1.00 67.17  ? 207 TRP A CE2 1 
ATOM   1204 C  CE3 . TRP A 1 207 ? 159.536 159.752 194.889 1.00 67.17  ? 207 TRP A CE3 1 
ATOM   1205 C  CZ2 . TRP A 1 207 ? 158.883 162.380 194.093 1.00 67.17  ? 207 TRP A CZ2 1 
ATOM   1206 C  CZ3 . TRP A 1 207 ? 160.373 160.486 194.080 1.00 67.17  ? 207 TRP A CZ3 1 
ATOM   1207 C  CH2 . TRP A 1 207 ? 160.045 161.787 193.691 1.00 67.17  ? 207 TRP A CH2 1 
ATOM   1208 N  N   . GLU A 1 208 ? 156.742 160.195 199.360 1.00 72.25  ? 208 GLU A N   1 
ATOM   1209 C  CA  . GLU A 1 208 ? 156.655 161.497 200.016 1.00 72.25  ? 208 GLU A CA  1 
ATOM   1210 C  C   . GLU A 1 208 ? 157.392 161.518 201.350 1.00 72.25  ? 208 GLU A C   1 
ATOM   1211 O  O   . GLU A 1 208 ? 158.058 162.503 201.680 1.00 72.25  ? 208 GLU A O   1 
ATOM   1212 C  CB  . GLU A 1 208 ? 155.192 161.888 200.221 1.00 72.25  ? 208 GLU A CB  1 
ATOM   1213 C  CG  . GLU A 1 208 ? 154.445 162.200 198.947 1.00 72.25  ? 208 GLU A CG  1 
ATOM   1214 C  CD  . GLU A 1 208 ? 153.113 162.876 199.207 1.00 72.25  ? 208 GLU A CD  1 
ATOM   1215 O  OE1 . GLU A 1 208 ? 152.324 162.350 200.018 1.00 72.25  ? 208 GLU A OE1 1 
ATOM   1216 O  OE2 . GLU A 1 208 ? 152.853 163.932 198.595 1.00 72.25  ? 208 GLU A OE2 1 
ATOM   1217 N  N   . HIS A 1 209 ? 157.275 160.453 202.144 1.00 74.89  ? 209 HIS A N   1 
ATOM   1218 C  CA  . HIS A 1 209 ? 157.794 160.501 203.505 1.00 74.89  ? 209 HIS A CA  1 
ATOM   1219 C  C   . HIS A 1 209 ? 159.121 159.777 203.692 1.00 74.89  ? 209 HIS A C   1 
ATOM   1220 O  O   . HIS A 1 209 ? 159.631 159.755 204.816 1.00 74.89  ? 209 HIS A O   1 
ATOM   1221 C  CB  . HIS A 1 209 ? 156.759 159.931 204.475 1.00 74.89  ? 209 HIS A CB  1 
ATOM   1222 C  CG  . HIS A 1 209 ? 155.437 160.627 204.419 1.00 74.89  ? 209 HIS A CG  1 
ATOM   1223 N  ND1 . HIS A 1 209 ? 155.190 161.804 205.089 1.00 74.89  ? 209 HIS A ND1 1 
ATOM   1224 C  CD2 . HIS A 1 209 ? 154.292 160.317 203.768 1.00 74.89  ? 209 HIS A CD2 1 
ATOM   1225 C  CE1 . HIS A 1 209 ? 153.948 162.189 204.857 1.00 74.89  ? 209 HIS A CE1 1 
ATOM   1226 N  NE2 . HIS A 1 209 ? 153.381 161.303 204.058 1.00 74.89  ? 209 HIS A NE2 1 
ATOM   1227 N  N   . ARG A 1 210 ? 159.689 159.186 202.660 1.00 72.06  ? 210 ARG A N   1 
ATOM   1228 C  CA  . ARG A 1 210 ? 161.022 158.629 202.818 1.00 72.06  ? 210 ARG A CA  1 
ATOM   1229 C  C   . ARG A 1 210 ? 161.973 159.056 201.714 1.00 72.06  ? 210 ARG A C   1 
ATOM   1230 O  O   . ARG A 1 210 ? 163.155 159.277 201.992 1.00 72.06  ? 210 ARG A O   1 
ATOM   1231 C  CB  . ARG A 1 210 ? 160.942 157.095 202.879 1.00 72.06  ? 210 ARG A CB  1 
ATOM   1232 C  CG  . ARG A 1 210 ? 162.256 156.398 203.203 1.00 72.06  ? 210 ARG A CG  1 
ATOM   1233 C  CD  . ARG A 1 210 ? 162.935 157.010 204.416 1.00 72.06  ? 210 ARG A CD  1 
ATOM   1234 N  NE  . ARG A 1 210 ? 163.832 156.066 205.071 1.00 72.06  ? 210 ARG A NE  1 
ATOM   1235 C  CZ  . ARG A 1 210 ? 165.086 155.847 204.702 1.00 72.06  ? 210 ARG A CZ  1 
ATOM   1236 N  NH1 . ARG A 1 210 ? 165.633 156.502 203.692 1.00 72.06  ? 210 ARG A NH1 1 
ATOM   1237 N  NH2 . ARG A 1 210 ? 165.811 154.952 205.366 1.00 72.06  ? 210 ARG A NH2 1 
ATOM   1238 N  N   . VAL A 1 211 ? 161.495 159.174 200.470 1.00 67.98  ? 211 VAL A N   1 
ATOM   1239 C  CA  . VAL A 1 211 ? 162.414 159.460 199.374 1.00 67.98  ? 211 VAL A CA  1 
ATOM   1240 C  C   . VAL A 1 211 ? 162.919 160.892 199.465 1.00 67.98  ? 211 VAL A C   1 
ATOM   1241 O  O   . VAL A 1 211 ? 164.113 161.152 199.287 1.00 67.98  ? 211 VAL A O   1 
ATOM   1242 C  CB  . VAL A 1 211 ? 161.746 159.162 198.021 1.00 67.98  ? 211 VAL A CB  1 
ATOM   1243 C  CG1 . VAL A 1 211 ? 162.592 159.680 196.875 1.00 67.98  ? 211 VAL A CG1 1 
ATOM   1244 C  CG2 . VAL A 1 211 ? 161.540 157.673 197.870 1.00 67.98  ? 211 VAL A CG2 1 
ATOM   1245 N  N   . LEU A 1 212 ? 162.038 161.836 199.790 1.00 67.94  ? 212 LEU A N   1 
ATOM   1246 C  CA  . LEU A 1 212 ? 162.449 163.225 199.913 1.00 67.94  ? 212 LEU A CA  1 
ATOM   1247 C  C   . LEU A 1 212 ? 161.923 163.947 201.148 1.00 67.94  ? 212 LEU A C   1 
ATOM   1248 O  O   . LEU A 1 212 ? 162.348 165.084 201.382 1.00 67.94  ? 212 LEU A O   1 
ATOM   1249 C  CB  . LEU A 1 212 ? 162.061 164.004 198.644 1.00 67.94  ? 212 LEU A CB  1 
ATOM   1250 C  CG  . LEU A 1 212 ? 160.609 164.070 198.168 1.00 67.94  ? 212 LEU A CG  1 
ATOM   1251 C  CD1 . LEU A 1 212 ? 159.834 165.220 198.770 1.00 67.94  ? 212 LEU A CD1 1 
ATOM   1252 C  CD2 . LEU A 1 212 ? 160.583 164.150 196.665 1.00 67.94  ? 212 LEU A CD2 1 
ATOM   1253 N  N   . ALA A 1 213 ? 161.031 163.333 201.935 1.00 72.62  ? 213 ALA A N   1 
ATOM   1254 C  CA  . ALA A 1 213 ? 160.530 163.865 203.209 1.00 72.62  ? 213 ALA A CA  1 
ATOM   1255 C  C   . ALA A 1 213 ? 159.892 165.245 203.018 1.00 72.62  ? 213 ALA A C   1 
ATOM   1256 O  O   . ALA A 1 213 ? 160.410 166.268 203.465 1.00 72.62  ? 213 ALA A O   1 
ATOM   1257 C  CB  . ALA A 1 213 ? 161.638 163.903 204.269 1.00 72.62  ? 213 ALA A CB  1 
ATOM   1258 N  N   . ILE A 1 214 ? 158.757 165.235 202.311 1.00 73.85  ? 214 ILE A N   1 
ATOM   1259 C  CA  . ILE A 1 214 ? 158.130 166.474 201.861 1.00 73.85  ? 214 ILE A CA  1 
ATOM   1260 C  C   . ILE A 1 214 ? 157.673 167.319 203.047 1.00 73.85  ? 214 ILE A C   1 
ATOM   1261 O  O   . ILE A 1 214 ? 157.204 166.804 204.072 1.00 73.85  ? 214 ILE A O   1 
ATOM   1262 C  CB  . ILE A 1 214 ? 156.973 166.161 200.892 1.00 73.85  ? 214 ILE A CB  1 
ATOM   1263 C  CG1 . ILE A 1 214 ? 156.476 167.432 200.198 1.00 73.85  ? 214 ILE A CG1 1 
ATOM   1264 C  CG2 . ILE A 1 214 ? 155.829 165.420 201.581 1.00 73.85  ? 214 ILE A CG2 1 
ATOM   1265 C  CD1 . ILE A 1 214 ? 157.499 168.071 199.292 1.00 73.85  ? 214 ILE A CD1 1 
ATOM   1266 N  N   . SER A 1 215 ? 157.874 168.628 202.931 1.00 81.50  ? 215 SER A N   1 
ATOM   1267 C  CA  . SER A 1 215 ? 157.458 169.598 203.928 1.00 81.50  ? 215 SER A CA  1 
ATOM   1268 C  C   . SER A 1 215 ? 156.253 170.376 203.416 1.00 81.50  ? 215 SER A C   1 
ATOM   1269 O  O   . SER A 1 215 ? 155.954 170.387 202.220 1.00 81.50  ? 215 SER A O   1 
ATOM   1270 C  CB  . SER A 1 215 ? 158.599 170.560 204.270 1.00 81.50  ? 215 SER A CB  1 
ATOM   1271 O  OG  . SER A 1 215 ? 158.796 171.500 203.229 1.00 81.50  ? 215 SER A OG  1 
ATOM   1272 N  N   . ASP A 1 216 ? 155.563 171.036 204.339 1.00 86.83  ? 216 ASP A N   1 
ATOM   1273 C  CA  . ASP A 1 216 ? 154.315 171.729 204.024 1.00 86.83  ? 216 ASP A CA  1 
ATOM   1274 C  C   . ASP A 1 216 ? 154.543 173.150 203.506 1.00 86.83  ? 216 ASP A C   1 
ATOM   1275 O  O   . ASP A 1 216 ? 153.961 174.114 204.000 1.00 86.83  ? 216 ASP A O   1 
ATOM   1276 C  CB  . ASP A 1 216 ? 153.404 171.716 205.248 1.00 86.83  ? 216 ASP A CB  1 
ATOM   1277 C  CG  . ASP A 1 216 ? 154.057 172.323 206.483 1.00 86.83  ? 216 ASP A CG  1 
ATOM   1278 O  OD1 . ASP A 1 216 ? 155.247 172.699 206.423 1.00 86.83  ? 216 ASP A OD1 1 
ATOM   1279 O  OD2 . ASP A 1 216 ? 153.372 172.421 207.523 1.00 86.83  ? 216 ASP A OD2 1 
ATOM   1280 N  N   . GLY A 1 217 ? 155.377 173.287 202.493 1.00 83.20  ? 217 GLY A N   1 
ATOM   1281 C  CA  . GLY A 1 217 ? 155.618 174.576 201.871 1.00 83.20  ? 217 GLY A CA  1 
ATOM   1282 C  C   . GLY A 1 217 ? 157.067 174.757 201.460 1.00 83.20  ? 217 GLY A C   1 
ATOM   1283 O  O   . GLY A 1 217 ? 157.981 174.112 201.964 1.00 83.20  ? 217 GLY A O   1 
ATOM   1284 N  N   . ILE A 1 218 ? 157.281 175.671 200.507 1.00 80.48  ? 218 ILE A N   1 
ATOM   1285 C  CA  . ILE A 1 218 ? 158.629 175.982 200.043 1.00 80.48  ? 218 ILE A CA  1 
ATOM   1286 C  C   . ILE A 1 218 ? 159.376 176.854 201.047 1.00 80.48  ? 218 ILE A C   1 
ATOM   1287 O  O   . ILE A 1 218 ? 160.612 176.874 201.052 1.00 80.48  ? 218 ILE A O   1 
ATOM   1288 C  CB  . ILE A 1 218 ? 158.568 176.645 198.650 1.00 80.48  ? 218 ILE A CB  1 
ATOM   1289 C  CG1 . ILE A 1 218 ? 159.935 176.619 197.963 1.00 80.48  ? 218 ILE A CG1 1 
ATOM   1290 C  CG2 . ILE A 1 218 ? 158.048 178.070 198.737 1.00 80.48  ? 218 ILE A CG2 1 
ATOM   1291 C  CD1 . ILE A 1 218 ? 159.912 177.143 196.552 1.00 80.48  ? 218 ILE A CD1 1 
ATOM   1292 N  N   . GLU A 1 219 ? 158.657 177.548 201.929 1.00 89.36  ? 219 GLU A N   1 
ATOM   1293 C  CA  . GLU A 1 219 ? 159.258 178.384 202.959 1.00 89.36  ? 219 GLU A CA  1 
ATOM   1294 C  C   . GLU A 1 219 ? 159.726 177.549 204.148 1.00 89.36  ? 219 GLU A C   1 
ATOM   1295 O  O   . GLU A 1 219 ? 160.411 178.062 205.040 1.00 89.36  ? 219 GLU A O   1 
ATOM   1296 C  CB  . GLU A 1 219 ? 158.232 179.456 203.369 1.00 89.36  ? 219 GLU A CB  1 
ATOM   1297 C  CG  . GLU A 1 219 ? 158.683 180.535 204.347 1.00 89.36  ? 219 GLU A CG  1 
ATOM   1298 C  CD  . GLU A 1 219 ? 157.591 181.554 204.616 1.00 89.36  ? 219 GLU A CD  1 
ATOM   1299 O  OE1 . GLU A 1 219 ? 156.481 181.391 204.067 1.00 89.36  ? 219 GLU A OE1 1 
ATOM   1300 O  OE2 . GLU A 1 219 ? 157.847 182.522 205.359 1.00 89.36  ? 219 GLU A OE2 1 
ATOM   1301 N  N   . HIS A 1 220 ? 159.455 176.248 204.119 1.00 86.58  ? 220 HIS A N   1 
ATOM   1302 C  CA  . HIS A 1 220 ? 159.729 175.351 205.229 1.00 86.58  ? 220 HIS A CA  1 
ATOM   1303 C  C   . HIS A 1 220 ? 160.810 174.355 204.842 1.00 86.58  ? 220 HIS A C   1 
ATOM   1304 O  O   . HIS A 1 220 ? 160.636 173.147 205.024 1.00 86.58  ? 220 HIS A O   1 
ATOM   1305 C  CB  . HIS A 1 220 ? 158.456 174.612 205.644 1.00 86.58  ? 220 HIS A CB  1 
ATOM   1306 C  CG  . HIS A 1 220 ? 157.721 175.253 206.777 1.00 86.58  ? 220 HIS A CG  1 
ATOM   1307 N  ND1 . HIS A 1 220 ? 158.158 175.184 208.082 1.00 86.58  ? 220 HIS A ND1 1 
ATOM   1308 C  CD2 . HIS A 1 220 ? 156.581 175.983 206.800 1.00 86.58  ? 220 HIS A CD2 1 
ATOM   1309 C  CE1 . HIS A 1 220 ? 157.314 175.838 208.861 1.00 86.58  ? 220 HIS A CE1 1 
ATOM   1310 N  NE2 . HIS A 1 220 ? 156.350 176.333 208.107 1.00 86.58  ? 220 HIS A NE2 1 
ATOM   1311 N  N   . ILE A 1 221 ? 161.912 174.853 204.276 1.00 80.61  ? 221 ILE A N   1 
ATOM   1312 C  CA  . ILE A 1 221 ? 163.046 174.017 203.896 1.00 80.61  ? 221 ILE A CA  1 
ATOM   1313 C  C   . ILE A 1 221 ? 163.637 173.375 205.142 1.00 80.61  ? 221 ILE A C   1 
ATOM   1314 O  O   . ILE A 1 221 ? 164.145 174.068 206.030 1.00 80.61  ? 221 ILE A O   1 
ATOM   1315 C  CB  . ILE A 1 221 ? 164.119 174.826 203.146 1.00 80.61  ? 221 ILE A CB  1 
ATOM   1316 C  CG1 . ILE A 1 221 ? 163.526 175.497 201.905 1.00 80.61  ? 221 ILE A CG1 1 
ATOM   1317 C  CG2 . ILE A 1 221 ? 165.301 173.934 202.788 1.00 80.61  ? 221 ILE A CG2 1 
ATOM   1318 C  CD1 . ILE A 1 221 ? 163.367 174.576 200.715 1.00 80.61  ? 221 ILE A CD1 1 
ATOM   1319 N  N   . GLY A 1 222 ? 163.573 172.053 205.218 1.00 79.82  ? 222 GLY A N   1 
ATOM   1320 C  CA  . GLY A 1 222 ? 164.040 171.317 206.372 1.00 79.82  ? 222 GLY A CA  1 
ATOM   1321 C  C   . GLY A 1 222 ? 165.503 170.946 206.276 1.00 79.82  ? 222 GLY A C   1 
ATOM   1322 O  O   . GLY A 1 222 ? 166.281 171.547 205.531 1.00 79.82  ? 222 GLY A O   1 
ATOM   1323 N  N   . ASN A 1 223 ? 165.880 169.938 207.057 1.00 82.90  ? 223 ASN A N   1 
ATOM   1324 C  CA  . ASN A 1 223 ? 167.255 169.465 207.065 1.00 82.90  ? 223 ASN A CA  1 
ATOM   1325 C  C   . ASN A 1 223 ? 167.589 168.751 205.760 1.00 82.90  ? 223 ASN A C   1 
ATOM   1326 O  O   . ASN A 1 223 ? 166.735 168.116 205.135 1.00 82.90  ? 223 ASN A O   1 
ATOM   1327 C  CB  . ASN A 1 223 ? 167.490 168.526 208.248 1.00 82.90  ? 223 ASN A CB  1 
ATOM   1328 C  CG  . ASN A 1 223 ? 167.235 169.196 209.583 1.00 82.90  ? 223 ASN A CG  1 
ATOM   1329 O  OD1 . ASN A 1 223 ? 167.602 170.353 209.790 1.00 82.90  ? 223 ASN A OD1 1 
ATOM   1330 N  ND2 . ASN A 1 223 ? 166.606 168.470 210.499 1.00 82.90  ? 223 ASN A ND2 1 
ATOM   1331 N  N   . LEU A 1 224 ? 168.847 168.871 205.348 1.00 82.38  ? 224 LEU A N   1 
ATOM   1332 C  CA  . LEU A 1 224 ? 169.304 168.225 204.127 1.00 82.38  ? 224 LEU A CA  1 
ATOM   1333 C  C   . LEU A 1 224 ? 169.368 166.714 204.313 1.00 82.38  ? 224 LEU A C   1 
ATOM   1334 O  O   . LEU A 1 224 ? 169.901 166.215 205.307 1.00 82.38  ? 224 LEU A O   1 
ATOM   1335 C  CB  . LEU A 1 224 ? 170.677 168.763 203.726 1.00 82.38  ? 224 LEU A CB  1 
ATOM   1336 C  CG  . LEU A 1 224 ? 171.365 168.100 202.532 1.00 82.38  ? 224 LEU A CG  1 
ATOM   1337 C  CD1 . LEU A 1 224 ? 170.498 168.186 201.290 1.00 82.38  ? 224 LEU A CD1 1 
ATOM   1338 C  CD2 . LEU A 1 224 ? 172.726 168.723 202.280 1.00 82.38  ? 224 LEU A CD2 1 
ATOM   1339 N  N   . ARG A 1 225 ? 168.817 165.987 203.345 1.00 80.03  ? 225 ARG A N   1 
ATOM   1340 C  CA  . ARG A 1 225 ? 168.850 164.529 203.361 1.00 80.03  ? 225 ARG A CA  1 
ATOM   1341 C  C   . ARG A 1 225 ? 170.246 164.074 202.958 1.00 80.03  ? 225 ARG A C   1 
ATOM   1342 O  O   . ARG A 1 225 ? 170.663 164.265 201.812 1.00 80.03  ? 225 ARG A O   1 
ATOM   1343 C  CB  . ARG A 1 225 ? 167.787 163.966 202.424 1.00 80.03  ? 225 ARG A CB  1 
ATOM   1344 C  CG  . ARG A 1 225 ? 166.398 164.516 202.678 1.00 80.03  ? 225 ARG A CG  1 
ATOM   1345 C  CD  . ARG A 1 225 ? 165.328 163.515 202.287 1.00 80.03  ? 225 ARG A CD  1 
ATOM   1346 N  NE  . ARG A 1 225 ? 165.617 162.168 202.761 1.00 80.03  ? 225 ARG A NE  1 
ATOM   1347 C  CZ  . ARG A 1 225 ? 165.341 161.727 203.980 1.00 80.03  ? 225 ARG A CZ  1 
ATOM   1348 N  NH1 . ARG A 1 225 ? 164.764 162.503 204.882 1.00 80.03  ? 225 ARG A NH1 1 
ATOM   1349 N  NH2 . ARG A 1 225 ? 165.645 160.473 204.299 1.00 80.03  ? 225 ARG A NH2 1 
ATOM   1350 N  N   . TRP A 1 226 ? 170.972 163.472 203.902 1.00 88.02  ? 226 TRP A N   1 
ATOM   1351 C  CA  . TRP A 1 226 ? 172.367 163.126 203.653 1.00 88.02  ? 226 TRP A CA  1 
ATOM   1352 C  C   . TRP A 1 226 ? 172.500 161.910 202.744 1.00 88.02  ? 226 TRP A C   1 
ATOM   1353 O  O   . TRP A 1 226 ? 173.457 161.827 201.964 1.00 88.02  ? 226 TRP A O   1 
ATOM   1354 C  CB  . TRP A 1 226 ? 173.085 162.892 204.981 1.00 88.02  ? 226 TRP A CB  1 
ATOM   1355 C  CG  . TRP A 1 226 ? 173.158 164.125 205.833 1.00 88.02  ? 226 TRP A CG  1 
ATOM   1356 C  CD1 . TRP A 1 226 ? 172.524 164.337 207.022 1.00 88.02  ? 226 TRP A CD1 1 
ATOM   1357 C  CD2 . TRP A 1 226 ? 173.912 165.315 205.565 1.00 88.02  ? 226 TRP A CD2 1 
ATOM   1358 N  NE1 . TRP A 1 226 ? 172.832 165.584 207.509 1.00 88.02  ? 226 TRP A NE1 1 
ATOM   1359 C  CE2 . TRP A 1 226 ? 173.683 166.205 206.633 1.00 88.02  ? 226 TRP A CE2 1 
ATOM   1360 C  CE3 . TRP A 1 226 ? 174.758 165.715 204.524 1.00 88.02  ? 226 TRP A CE3 1 
ATOM   1361 C  CZ2 . TRP A 1 226 ? 174.268 167.468 206.692 1.00 88.02  ? 226 TRP A CZ2 1 
ATOM   1362 C  CZ3 . TRP A 1 226 ? 175.337 166.969 204.584 1.00 88.02  ? 226 TRP A CZ3 1 
ATOM   1363 C  CH2 . TRP A 1 226 ? 175.090 167.830 205.660 1.00 88.02  ? 226 TRP A CH2 1 
ATOM   1364 N  N   . GLU A 1 227 ? 171.563 160.961 202.836 1.00 84.27  ? 227 GLU A N   1 
ATOM   1365 C  CA  . GLU A 1 227 ? 171.578 159.812 201.936 1.00 84.27  ? 227 GLU A CA  1 
ATOM   1366 C  C   . GLU A 1 227 ? 171.368 160.249 200.493 1.00 84.27  ? 227 GLU A C   1 
ATOM   1367 O  O   . GLU A 1 227 ? 172.042 159.759 199.578 1.00 84.27  ? 227 GLU A O   1 
ATOM   1368 C  CB  . GLU A 1 227 ? 170.509 158.805 202.359 1.00 84.27  ? 227 GLU A CB  1 
ATOM   1369 C  CG  . GLU A 1 227 ? 170.377 157.599 201.441 1.00 84.27  ? 227 GLU A CG  1 
ATOM   1370 C  CD  . GLU A 1 227 ? 171.684 156.847 201.255 1.00 84.27  ? 227 GLU A CD  1 
ATOM   1371 O  OE1 . GLU A 1 227 ? 172.360 156.564 202.266 1.00 84.27  ? 227 GLU A OE1 1 
ATOM   1372 O  OE2 . GLU A 1 227 ? 172.033 156.534 200.097 1.00 84.27  ? 227 GLU A OE2 1 
ATOM   1373 N  N   . LEU A 1 228 ? 170.456 161.197 200.275 1.00 82.17  ? 228 LEU A N   1 
ATOM   1374 C  CA  . LEU A 1 228 ? 170.272 161.760 198.944 1.00 82.17  ? 228 LEU A CA  1 
ATOM   1375 C  C   . LEU A 1 228 ? 171.493 162.546 198.487 1.00 82.17  ? 228 LEU A C   1 
ATOM   1376 O  O   . LEU A 1 228 ? 171.798 162.567 197.291 1.00 82.17  ? 228 LEU A O   1 
ATOM   1377 C  CB  . LEU A 1 228 ? 169.042 162.658 198.923 1.00 82.17  ? 228 LEU A CB  1 
ATOM   1378 C  CG  . LEU A 1 228 ? 167.666 162.007 198.959 1.00 82.17  ? 228 LEU A CG  1 
ATOM   1379 C  CD1 . LEU A 1 228 ? 166.629 163.093 198.820 1.00 82.17  ? 228 LEU A CD1 1 
ATOM   1380 C  CD2 . LEU A 1 228 ? 167.528 160.981 197.856 1.00 82.17  ? 228 LEU A CD2 1 
ATOM   1381 N  N   . ALA A 1 229 ? 172.192 163.203 199.416 1.00 85.64  ? 229 ALA A N   1 
ATOM   1382 C  CA  . ALA A 1 229 ? 173.419 163.908 199.057 1.00 85.64  ? 229 ALA A CA  1 
ATOM   1383 C  C   . ALA A 1 229 ? 174.496 162.937 198.592 1.00 85.64  ? 229 ALA A C   1 
ATOM   1384 O  O   . ALA A 1 229 ? 175.200 163.205 197.610 1.00 85.64  ? 229 ALA A O   1 
ATOM   1385 C  CB  . ALA A 1 229 ? 173.913 164.736 200.240 1.00 85.64  ? 229 ALA A CB  1 
ATOM   1386 N  N   . LEU A 1 230 ? 174.630 161.799 199.278 1.00 87.58  ? 230 LEU A N   1 
ATOM   1387 C  CA  . LEU A 1 230 ? 175.556 160.766 198.824 1.00 87.58  ? 230 LEU A CA  1 
ATOM   1388 C  C   . LEU A 1 230 ? 175.129 160.178 197.485 1.00 87.58  ? 230 LEU A C   1 
ATOM   1389 O  O   . LEU A 1 230 ? 175.986 159.861 196.652 1.00 87.58  ? 230 LEU A O   1 
ATOM   1390 C  CB  . LEU A 1 230 ? 175.680 159.658 199.871 1.00 87.58  ? 230 LEU A CB  1 
ATOM   1391 C  CG  . LEU A 1 230 ? 176.810 159.763 200.899 1.00 87.58  ? 230 LEU A CG  1 
ATOM   1392 C  CD1 . LEU A 1 230 ? 178.159 159.694 200.200 1.00 87.58  ? 230 LEU A CD1 1 
ATOM   1393 C  CD2 . LEU A 1 230 ? 176.710 161.019 201.756 1.00 87.58  ? 230 LEU A CD2 1 
ATOM   1394 N  N   . CYS A 1 231 ? 173.820 160.027 197.263 1.00 85.22  ? 231 CYS A N   1 
ATOM   1395 C  CA  . CYS A 1 231 ? 173.331 159.547 195.972 1.00 85.22  ? 231 CYS A CA  1 
ATOM   1396 C  C   . CYS A 1 231 ? 173.676 160.520 194.849 1.00 85.22  ? 231 CYS A C   1 
ATOM   1397 O  O   . CYS A 1 231 ? 174.089 160.104 193.759 1.00 85.22  ? 231 CYS A O   1 
ATOM   1398 C  CB  . CYS A 1 231 ? 171.822 159.320 196.036 1.00 85.22  ? 231 CYS A CB  1 
ATOM   1399 S  SG  . CYS A 1 231 ? 171.323 157.888 197.016 1.00 85.22  ? 231 CYS A SG  1 
ATOM   1400 N  N   . LEU A 1 232 ? 173.516 161.822 195.101 1.00 87.04  ? 232 LEU A N   1 
ATOM   1401 C  CA  . LEU A 1 232 ? 173.868 162.828 194.103 1.00 87.04  ? 232 LEU A CA  1 
ATOM   1402 C  C   . LEU A 1 232 ? 175.369 162.862 193.850 1.00 87.04  ? 232 LEU A C   1 
ATOM   1403 O  O   . LEU A 1 232 ? 175.806 163.050 192.707 1.00 87.04  ? 232 LEU A O   1 
ATOM   1404 C  CB  . LEU A 1 232 ? 173.374 164.203 194.543 1.00 87.04  ? 232 LEU A CB  1 
ATOM   1405 C  CG  . LEU A 1 232 ? 173.395 165.261 193.444 1.00 87.04  ? 232 LEU A CG  1 
ATOM   1406 C  CD1 . LEU A 1 232 ? 172.444 164.867 192.340 1.00 87.04  ? 232 LEU A CD1 1 
ATOM   1407 C  CD2 . LEU A 1 232 ? 173.038 166.623 193.998 1.00 87.04  ? 232 LEU A CD2 1 
ATOM   1408 N  N   . LEU A 1 233 ? 176.174 162.690 194.904 1.00 89.01  ? 233 LEU A N   1 
ATOM   1409 C  CA  . LEU A 1 233 ? 177.622 162.621 194.731 1.00 89.01  ? 233 LEU A CA  1 
ATOM   1410 C  C   . LEU A 1 233 ? 178.020 161.408 193.899 1.00 89.01  ? 233 LEU A C   1 
ATOM   1411 O  O   . LEU A 1 233 ? 178.905 161.498 193.040 1.00 89.01  ? 233 LEU A O   1 
ATOM   1412 C  CB  . LEU A 1 233 ? 178.312 162.590 196.094 1.00 89.01  ? 233 LEU A CB  1 
ATOM   1413 C  CG  . LEU A 1 233 ? 179.798 162.228 196.114 1.00 89.01  ? 233 LEU A CG  1 
ATOM   1414 C  CD1 . LEU A 1 233 ? 180.626 163.357 195.525 1.00 89.01  ? 233 LEU A CD1 1 
ATOM   1415 C  CD2 . LEU A 1 233 ? 180.257 161.903 197.525 1.00 89.01  ? 233 LEU A CD2 1 
ATOM   1416 N  N   . ALA A 1 234 ? 177.367 160.266 194.135 1.00 91.13  ? 234 ALA A N   1 
ATOM   1417 C  CA  . ALA A 1 234 ? 177.633 159.073 193.337 1.00 91.13  ? 234 ALA A CA  1 
ATOM   1418 C  C   . ALA A 1 234 ? 177.236 159.278 191.880 1.00 91.13  ? 234 ALA A C   1 
ATOM   1419 O  O   . ALA A 1 234 ? 177.957 158.853 190.968 1.00 91.13  ? 234 ALA A O   1 
ATOM   1420 C  CB  . ALA A 1 234 ? 176.898 157.871 193.929 1.00 91.13  ? 234 ALA A CB  1 
ATOM   1421 N  N   . ALA A 1 235 ? 176.096 159.933 191.643 1.00 91.22  ? 235 ALA A N   1 
ATOM   1422 C  CA  . ALA A 1 235 ? 175.669 160.209 190.274 1.00 91.22  ? 235 ALA A CA  1 
ATOM   1423 C  C   . ALA A 1 235 ? 176.641 161.143 189.565 1.00 91.22  ? 235 ALA A C   1 
ATOM   1424 O  O   . ALA A 1 235 ? 176.985 160.926 188.396 1.00 91.22  ? 235 ALA A O   1 
ATOM   1425 C  CB  . ALA A 1 235 ? 174.261 160.801 190.272 1.00 91.22  ? 235 ALA A CB  1 
ATOM   1426 N  N   . TRP A 1 236 ? 177.119 162.174 190.262 1.00 96.31  ? 236 TRP A N   1 
ATOM   1427 C  CA  . TRP A 1 236 ? 178.059 163.095 189.634 1.00 96.31  ? 236 TRP A CA  1 
ATOM   1428 C  C   . TRP A 1 236 ? 179.414 162.440 189.392 1.00 96.31  ? 236 TRP A C   1 
ATOM   1429 O  O   . TRP A 1 236 ? 180.051 162.697 188.365 1.00 96.31  ? 236 TRP A O   1 
ATOM   1430 C  CB  . TRP A 1 236 ? 178.209 164.363 190.471 1.00 96.31  ? 236 TRP A CB  1 
ATOM   1431 C  CG  . TRP A 1 236 ? 177.335 165.473 189.986 1.00 96.31  ? 236 TRP A CG  1 
ATOM   1432 C  CD1 . TRP A 1 236 ? 176.326 166.076 190.672 1.00 96.31  ? 236 TRP A CD1 1 
ATOM   1433 C  CD2 . TRP A 1 236 ? 177.387 166.111 188.704 1.00 96.31  ? 236 TRP A CD2 1 
ATOM   1434 N  NE1 . TRP A 1 236 ? 175.744 167.051 189.900 1.00 96.31  ? 236 TRP A NE1 1 
ATOM   1435 C  CE2 . TRP A 1 236 ? 176.379 167.092 188.687 1.00 96.31  ? 236 TRP A CE2 1 
ATOM   1436 C  CE3 . TRP A 1 236 ? 178.190 165.951 187.570 1.00 96.31  ? 236 TRP A CE3 1 
ATOM   1437 C  CZ2 . TRP A 1 236 ? 176.149 167.905 187.582 1.00 96.31  ? 236 TRP A CZ2 1 
ATOM   1438 C  CZ3 . TRP A 1 236 ? 177.960 166.760 186.475 1.00 96.31  ? 236 TRP A CZ3 1 
ATOM   1439 C  CH2 . TRP A 1 236 ? 176.950 167.726 186.489 1.00 96.31  ? 236 TRP A CH2 1 
ATOM   1440 N  N   . THR A 1 237 ? 179.868 161.575 190.303 1.00 97.89  ? 237 THR A N   1 
ATOM   1441 C  CA  . THR A 1 237 ? 181.166 160.950 190.078 1.00 97.89  ? 237 THR A CA  1 
ATOM   1442 C  C   . THR A 1 237 ? 181.089 159.865 189.007 1.00 97.89  ? 237 THR A C   1 
ATOM   1443 O  O   . THR A 1 237 ? 182.062 159.664 188.273 1.00 97.89  ? 237 THR A O   1 
ATOM   1444 C  CB  . THR A 1 237 ? 181.755 160.417 191.394 1.00 97.89  ? 237 THR A CB  1 
ATOM   1445 O  OG1 . THR A 1 237 ? 183.146 160.128 191.209 1.00 97.89  ? 237 THR A OG1 1 
ATOM   1446 C  CG2 . THR A 1 237 ? 181.059 159.161 191.880 1.00 97.89  ? 237 THR A CG2 1 
ATOM   1447 N  N   . ILE A 1 238 ? 179.937 159.209 188.836 1.00 99.06  ? 238 ILE A N   1 
ATOM   1448 C  CA  . ILE A 1 238 ? 179.850 158.258 187.733 1.00 99.06  ? 238 ILE A CA  1 
ATOM   1449 C  C   . ILE A 1 238 ? 179.667 158.998 186.408 1.00 99.06  ? 238 ILE A C   1 
ATOM   1450 O  O   . ILE A 1 238 ? 180.140 158.528 185.366 1.00 99.06  ? 238 ILE A O   1 
ATOM   1451 C  CB  . ILE A 1 238 ? 178.750 157.204 187.986 1.00 99.06  ? 238 ILE A CB  1 
ATOM   1452 C  CG1 . ILE A 1 238 ? 178.886 156.036 187.009 1.00 99.06  ? 238 ILE A CG1 1 
ATOM   1453 C  CG2 . ILE A 1 238 ? 177.359 157.783 187.876 1.00 99.06  ? 238 ILE A CG2 1 
ATOM   1454 C  CD1 . ILE A 1 238 ? 178.045 154.836 187.381 1.00 99.06  ? 238 ILE A CD1 1 
ATOM   1455 N  N   . CYS A 1 239 ? 179.046 160.185 186.422 1.00 104.69 ? 239 CYS A N   1 
ATOM   1456 C  CA  . CYS A 1 239 ? 179.008 161.006 185.215 1.00 104.69 ? 239 CYS A CA  1 
ATOM   1457 C  C   . CYS A 1 239 ? 180.401 161.505 184.843 1.00 104.69 ? 239 CYS A C   1 
ATOM   1458 O  O   . CYS A 1 239 ? 180.759 161.542 183.659 1.00 104.69 ? 239 CYS A O   1 
ATOM   1459 C  CB  . CYS A 1 239 ? 178.048 162.180 185.410 1.00 104.69 ? 239 CYS A CB  1 
ATOM   1460 S  SG  . CYS A 1 239 ? 178.176 163.474 184.157 1.00 104.69 ? 239 CYS A SG  1 
ATOM   1461 N  N   . TYR A 1 240 ? 181.201 161.883 185.843 1.00 113.81 ? 240 TYR A N   1 
ATOM   1462 C  CA  . TYR A 1 240 ? 182.578 162.292 185.587 1.00 113.81 ? 240 TYR A CA  1 
ATOM   1463 C  C   . TYR A 1 240 ? 183.432 161.131 185.096 1.00 113.81 ? 240 TYR A C   1 
ATOM   1464 O  O   . TYR A 1 240 ? 184.328 161.332 184.268 1.00 113.81 ? 240 TYR A O   1 
ATOM   1465 C  CB  . TYR A 1 240 ? 183.186 162.903 186.849 1.00 113.81 ? 240 TYR A CB  1 
ATOM   1466 C  CG  . TYR A 1 240 ? 184.525 163.560 186.624 1.00 113.81 ? 240 TYR A CG  1 
ATOM   1467 C  CD1 . TYR A 1 240 ? 184.610 164.842 186.097 1.00 113.81 ? 240 TYR A CD1 1 
ATOM   1468 C  CD2 . TYR A 1 240 ? 185.706 162.903 186.944 1.00 113.81 ? 240 TYR A CD2 1 
ATOM   1469 C  CE1 . TYR A 1 240 ? 185.833 165.447 185.888 1.00 113.81 ? 240 TYR A CE1 1 
ATOM   1470 C  CE2 . TYR A 1 240 ? 186.934 163.500 186.740 1.00 113.81 ? 240 TYR A CE2 1 
ATOM   1471 C  CZ  . TYR A 1 240 ? 186.991 164.774 186.212 1.00 113.81 ? 240 TYR A CZ  1 
ATOM   1472 O  OH  . TYR A 1 240 ? 188.210 165.378 186.006 1.00 113.81 ? 240 TYR A OH  1 
ATOM   1473 N  N   . PHE A 1 241 ? 183.188 159.921 185.607 1.00 115.75 ? 241 PHE A N   1 
ATOM   1474 C  CA  . PHE A 1 241 ? 183.878 158.745 185.086 1.00 115.75 ? 241 PHE A CA  1 
ATOM   1475 C  C   . PHE A 1 241 ? 183.481 158.475 183.640 1.00 115.75 ? 241 PHE A C   1 
ATOM   1476 O  O   . PHE A 1 241 ? 184.325 158.103 182.818 1.00 115.75 ? 241 PHE A O   1 
ATOM   1477 C  CB  . PHE A 1 241 ? 183.585 157.531 185.968 1.00 115.75 ? 241 PHE A CB  1 
ATOM   1478 C  CG  . PHE A 1 241 ? 183.768 156.211 185.272 1.00 115.75 ? 241 PHE A CG  1 
ATOM   1479 C  CD1 . PHE A 1 241 ? 185.039 155.733 184.991 1.00 115.75 ? 241 PHE A CD1 1 
ATOM   1480 C  CD2 . PHE A 1 241 ? 182.672 155.442 184.910 1.00 115.75 ? 241 PHE A CD2 1 
ATOM   1481 C  CE1 . PHE A 1 241 ? 185.213 154.518 184.354 1.00 115.75 ? 241 PHE A CE1 1 
ATOM   1482 C  CE2 . PHE A 1 241 ? 182.839 154.226 184.272 1.00 115.75 ? 241 PHE A CE2 1 
ATOM   1483 C  CZ  . PHE A 1 241 ? 184.111 153.764 183.995 1.00 115.75 ? 241 PHE A CZ  1 
ATOM   1484 N  N   . CYS A 1 242 ? 182.196 158.655 183.315 1.00 115.98 ? 242 CYS A N   1 
ATOM   1485 C  CA  . CYS A 1 242 ? 181.747 158.511 181.933 1.00 115.98 ? 242 CYS A CA  1 
ATOM   1486 C  C   . CYS A 1 242 ? 182.359 159.574 181.031 1.00 115.98 ? 242 CYS A C   1 
ATOM   1487 O  O   . CYS A 1 242 ? 182.563 159.330 179.836 1.00 115.98 ? 242 CYS A O   1 
ATOM   1488 C  CB  . CYS A 1 242 ? 180.221 158.577 181.864 1.00 115.98 ? 242 CYS A CB  1 
ATOM   1489 S  SG  . CYS A 1 242 ? 179.381 157.016 182.214 1.00 115.98 ? 242 CYS A SG  1 
ATOM   1490 N  N   . ILE A 1 243 ? 182.640 160.758 181.579 1.00 118.02 ? 243 ILE A N   1 
ATOM   1491 C  CA  . ILE A 1 243 ? 183.330 161.796 180.816 1.00 118.02 ? 243 ILE A CA  1 
ATOM   1492 C  C   . ILE A 1 243 ? 184.751 161.356 180.477 1.00 118.02 ? 243 ILE A C   1 
ATOM   1493 O  O   . ILE A 1 243 ? 185.195 161.460 179.328 1.00 118.02 ? 243 ILE A O   1 
ATOM   1494 C  CB  . ILE A 1 243 ? 183.316 163.125 181.593 1.00 118.02 ? 243 ILE A CB  1 
ATOM   1495 C  CG1 . ILE A 1 243 ? 181.950 163.802 181.476 1.00 118.02 ? 243 ILE A CG1 1 
ATOM   1496 C  CG2 . ILE A 1 243 ? 184.418 164.054 181.110 1.00 118.02 ? 243 ILE A CG2 1 
ATOM   1497 C  CD1 . ILE A 1 243 ? 181.662 164.339 180.095 1.00 118.02 ? 243 ILE A CD1 1 
ATOM   1498 N  N   . TRP A 1 244 ? 185.478 160.836 181.467 1.00 126.59 ? 244 TRP A N   1 
ATOM   1499 C  CA  . TRP A 1 244 ? 186.883 160.502 181.255 1.00 126.59 ? 244 TRP A CA  1 
ATOM   1500 C  C   . TRP A 1 244 ? 187.039 159.188 180.498 1.00 126.59 ? 244 TRP A C   1 
ATOM   1501 O  O   . TRP A 1 244 ? 187.570 159.161 179.383 1.00 126.59 ? 244 TRP A O   1 
ATOM   1502 C  CB  . TRP A 1 244 ? 187.615 160.434 182.597 1.00 126.59 ? 244 TRP A CB  1 
ATOM   1503 C  CG  . TRP A 1 244 ? 189.068 160.778 182.501 1.00 126.59 ? 244 TRP A CG  1 
ATOM   1504 C  CD1 . TRP A 1 244 ? 189.763 161.088 181.369 1.00 126.59 ? 244 TRP A CD1 1 
ATOM   1505 C  CD2 . TRP A 1 244 ? 190.010 160.836 183.578 1.00 126.59 ? 244 TRP A CD2 1 
ATOM   1506 N  NE1 . TRP A 1 244 ? 191.078 161.342 181.674 1.00 126.59 ? 244 TRP A NE1 1 
ATOM   1507 C  CE2 . TRP A 1 244 ? 191.256 161.193 183.025 1.00 126.59 ? 244 TRP A CE2 1 
ATOM   1508 C  CE3 . TRP A 1 244 ? 189.921 160.624 184.957 1.00 126.59 ? 244 TRP A CE3 1 
ATOM   1509 C  CZ2 . TRP A 1 244 ? 192.402 161.342 183.801 1.00 126.59 ? 244 TRP A CZ2 1 
ATOM   1510 C  CZ3 . TRP A 1 244 ? 191.060 160.773 185.727 1.00 126.59 ? 244 TRP A CZ3 1 
ATOM   1511 C  CH2 . TRP A 1 244 ? 192.284 161.128 185.147 1.00 126.59 ? 244 TRP A CH2 1 
ATOM   1512 N  N   . LYS A 1 245 ? 186.578 158.091 181.086 1.00 127.48 ? 245 LYS A N   1 
ATOM   1513 C  CA  . LYS A 1 245 ? 186.723 156.758 180.506 1.00 127.48 ? 245 LYS A CA  1 
ATOM   1514 C  C   . LYS A 1 245 ? 185.333 156.252 180.137 1.00 127.48 ? 245 LYS A C   1 
ATOM   1515 O  O   . LYS A 1 245 ? 184.542 155.884 181.010 1.00 127.48 ? 245 LYS A O   1 
ATOM   1516 C  CB  . LYS A 1 245 ? 187.429 155.819 181.480 1.00 127.48 ? 245 LYS A CB  1 
ATOM   1517 C  CG  . LYS A 1 245 ? 187.652 154.414 180.947 1.00 127.48 ? 245 LYS A CG  1 
ATOM   1518 C  CD  . LYS A 1 245 ? 188.057 153.465 182.064 1.00 127.48 ? 245 LYS A CD  1 
ATOM   1519 C  CE  . LYS A 1 245 ? 188.402 152.087 181.523 1.00 127.48 ? 245 LYS A CE  1 
ATOM   1520 N  NZ  . LYS A 1 245 ? 189.050 151.234 182.558 1.00 127.48 ? 245 LYS A NZ  1 
ATOM   1521 N  N   . GLY A 1 246 ? 185.046 156.216 178.840 1.00 134.95 ? 246 GLY A N   1 
ATOM   1522 C  CA  . GLY A 1 246 ? 183.723 155.857 178.374 1.00 134.95 ? 246 GLY A CA  1 
ATOM   1523 C  C   . GLY A 1 246 ? 183.320 156.618 177.130 1.00 134.95 ? 246 GLY A C   1 
ATOM   1524 O  O   . GLY A 1 246 ? 182.279 156.334 176.529 1.00 134.95 ? 246 GLY A O   1 
ATOM   1525 N  N   . THR A 1 247 ? 184.137 157.600 176.738 1.00 138.85 ? 247 THR A N   1 
ATOM   1526 C  CA  . THR A 1 247 ? 183.920 158.274 175.462 1.00 138.85 ? 247 THR A CA  1 
ATOM   1527 C  C   . THR A 1 247 ? 184.190 157.343 174.288 1.00 138.85 ? 247 THR A C   1 
ATOM   1528 O  O   . THR A 1 247 ? 183.612 157.522 173.210 1.00 138.85 ? 247 THR A O   1 
ATOM   1529 C  CB  . THR A 1 247 ? 184.799 159.520 175.361 1.00 138.85 ? 247 THR A CB  1 
ATOM   1530 O  OG1 . THR A 1 247 ? 186.141 159.195 175.745 1.00 138.85 ? 247 THR A OG1 1 
ATOM   1531 C  CG2 . THR A 1 247 ? 184.269 160.621 176.263 1.00 138.85 ? 247 THR A CG2 1 
ATOM   1532 N  N   . LYS A 1 248 ? 185.057 156.351 174.476 1.00 143.73 ? 248 LYS A N   1 
ATOM   1533 C  CA  . LYS A 1 248 ? 185.314 155.338 173.455 1.00 143.73 ? 248 LYS A CA  1 
ATOM   1534 C  C   . LYS A 1 248 ? 184.106 154.414 173.383 1.00 143.73 ? 248 LYS A C   1 
ATOM   1535 O  O   . LYS A 1 248 ? 183.981 153.465 174.161 1.00 143.73 ? 248 LYS A O   1 
ATOM   1536 C  CB  . LYS A 1 248 ? 186.590 154.569 173.781 1.00 143.73 ? 248 LYS A CB  1 
ATOM   1537 C  CG  . LYS A 1 248 ? 187.798 155.460 174.031 1.00 143.73 ? 248 LYS A CG  1 
ATOM   1538 C  CD  . LYS A 1 248 ? 188.782 154.814 174.994 1.00 143.73 ? 248 LYS A CD  1 
ATOM   1539 C  CE  . LYS A 1 248 ? 188.161 154.602 176.366 1.00 143.73 ? 248 LYS A CE  1 
ATOM   1540 N  NZ  . LYS A 1 248 ? 189.036 153.785 177.252 1.00 143.73 ? 248 LYS A NZ  1 
ATOM   1541 N  N   . SER A 1 249 ? 183.210 154.691 172.441 1.00 146.59 ? 249 SER A N   1 
ATOM   1542 C  CA  . SER A 1 249 ? 181.936 153.999 172.335 1.00 146.59 ? 249 SER A CA  1 
ATOM   1543 C  C   . SER A 1 249 ? 182.095 152.721 171.511 1.00 146.59 ? 249 SER A C   1 
ATOM   1544 O  O   . SER A 1 249 ? 183.208 152.239 171.280 1.00 146.59 ? 249 SER A O   1 
ATOM   1545 C  CB  . SER A 1 249 ? 180.883 154.931 171.739 1.00 146.59 ? 249 SER A CB  1 
ATOM   1546 O  OG  . SER A 1 249 ? 180.591 155.999 172.624 1.00 146.59 ? 249 SER A OG  1 
ATOM   1547 N  N   . THR A 1 250 ? 180.958 152.147 171.097 1.00 144.46 ? 250 THR A N   1 
ATOM   1548 C  CA  . THR A 1 250 ? 180.836 150.939 170.278 1.00 144.46 ? 250 THR A CA  1 
ATOM   1549 C  C   . THR A 1 250 ? 181.453 149.710 170.940 1.00 144.46 ? 250 THR A C   1 
ATOM   1550 O  O   . THR A 1 250 ? 181.866 149.754 172.104 1.00 144.46 ? 250 THR A O   1 
ATOM   1551 C  CB  . THR A 1 250 ? 181.440 151.138 168.878 1.00 144.46 ? 250 THR A CB  1 
ATOM   1552 O  OG1 . THR A 1 250 ? 182.870 151.201 168.964 1.00 144.46 ? 250 THR A OG1 1 
ATOM   1553 C  CG2 . THR A 1 250 ? 180.907 152.414 168.232 1.00 144.46 ? 250 THR A CG2 1 
ATOM   1554 N  N   . GLY A 1 251 ? 181.499 148.601 170.207 1.00 140.61 ? 251 GLY A N   1 
ATOM   1555 C  CA  . GLY A 1 251 ? 181.951 147.343 170.767 1.00 140.61 ? 251 GLY A CA  1 
ATOM   1556 C  C   . GLY A 1 251 ? 180.791 146.461 171.182 1.00 140.61 ? 251 GLY A C   1 
ATOM   1557 O  O   . GLY A 1 251 ? 179.730 146.489 170.553 1.00 140.61 ? 251 GLY A O   1 
ATOM   1558 N  N   . LYS A 1 252 ? 180.978 145.676 172.239 1.00 136.75 ? 252 LYS A N   1 
ATOM   1559 C  CA  . LYS A 1 252 ? 179.926 144.815 172.761 1.00 136.75 ? 252 LYS A CA  1 
ATOM   1560 C  C   . LYS A 1 252 ? 179.028 145.516 173.772 1.00 136.75 ? 252 LYS A C   1 
ATOM   1561 O  O   . LYS A 1 252 ? 178.062 144.908 174.246 1.00 136.75 ? 252 LYS A O   1 
ATOM   1562 C  CB  . LYS A 1 252 ? 180.535 143.562 173.400 1.00 136.75 ? 252 LYS A CB  1 
ATOM   1563 C  CG  . LYS A 1 252 ? 181.479 142.796 172.491 1.00 136.75 ? 252 LYS A CG  1 
ATOM   1564 C  CD  . LYS A 1 252 ? 180.711 142.078 171.391 1.00 136.75 ? 252 LYS A CD  1 
ATOM   1565 C  CE  . LYS A 1 252 ? 181.637 141.262 170.506 1.00 136.75 ? 252 LYS A CE  1 
ATOM   1566 N  NZ  . LYS A 1 252 ? 181.045 141.021 169.162 1.00 136.75 ? 252 LYS A NZ  1 
ATOM   1567 N  N   . VAL A 1 253 ? 179.317 146.772 174.113 1.00 136.46 ? 253 VAL A N   1 
ATOM   1568 C  CA  . VAL A 1 253 ? 178.513 147.483 175.100 1.00 136.46 ? 253 VAL A CA  1 
ATOM   1569 C  C   . VAL A 1 253 ? 177.300 148.177 174.492 1.00 136.46 ? 253 VAL A C   1 
ATOM   1570 O  O   . VAL A 1 253 ? 176.357 148.507 175.225 1.00 136.46 ? 253 VAL A O   1 
ATOM   1571 C  CB  . VAL A 1 253 ? 179.369 148.510 175.864 1.00 136.46 ? 253 VAL A CB  1 
ATOM   1572 C  CG1 . VAL A 1 253 ? 180.444 147.804 176.675 1.00 136.46 ? 253 VAL A CG1 1 
ATOM   1573 C  CG2 . VAL A 1 253 ? 179.993 149.507 174.899 1.00 136.46 ? 253 VAL A CG2 1 
ATOM   1574 N  N   . VAL A 1 254 ? 177.289 148.405 173.178 1.00 132.29 ? 254 VAL A N   1 
ATOM   1575 C  CA  . VAL A 1 254 ? 176.159 149.077 172.546 1.00 132.29 ? 254 VAL A CA  1 
ATOM   1576 C  C   . VAL A 1 254 ? 175.064 148.109 172.112 1.00 132.29 ? 254 VAL A C   1 
ATOM   1577 O  O   . VAL A 1 254 ? 173.914 148.533 171.934 1.00 132.29 ? 254 VAL A O   1 
ATOM   1578 C  CB  . VAL A 1 254 ? 176.618 149.909 171.337 1.00 132.29 ? 254 VAL A CB  1 
ATOM   1579 C  CG1 . VAL A 1 254 ? 177.330 151.169 171.802 1.00 132.29 ? 254 VAL A CG1 1 
ATOM   1580 C  CG2 . VAL A 1 254 ? 177.520 149.081 170.436 1.00 132.29 ? 254 VAL A CG2 1 
ATOM   1581 N  N   . TYR A 1 255 ? 175.382 146.827 171.937 1.00 130.46 ? 255 TYR A N   1 
ATOM   1582 C  CA  . TYR A 1 255 ? 174.373 145.844 171.567 1.00 130.46 ? 255 TYR A CA  1 
ATOM   1583 C  C   . TYR A 1 255 ? 173.459 145.470 172.724 1.00 130.46 ? 255 TYR A C   1 
ATOM   1584 O  O   . TYR A 1 255 ? 172.365 144.948 172.485 1.00 130.46 ? 255 TYR A O   1 
ATOM   1585 C  CB  . TYR A 1 255 ? 175.043 144.582 171.016 1.00 130.46 ? 255 TYR A CB  1 
ATOM   1586 C  CG  . TYR A 1 255 ? 175.663 144.762 169.649 1.00 130.46 ? 255 TYR A CG  1 
ATOM   1587 C  CD1 . TYR A 1 255 ? 176.959 145.245 169.510 1.00 130.46 ? 255 TYR A CD1 1 
ATOM   1588 C  CD2 . TYR A 1 255 ? 174.952 144.451 168.497 1.00 130.46 ? 255 TYR A CD2 1 
ATOM   1589 C  CE1 . TYR A 1 255 ? 177.530 145.412 168.262 1.00 130.46 ? 255 TYR A CE1 1 
ATOM   1590 C  CE2 . TYR A 1 255 ? 175.514 144.615 167.244 1.00 130.46 ? 255 TYR A CE2 1 
ATOM   1591 C  CZ  . TYR A 1 255 ? 176.803 145.095 167.133 1.00 130.46 ? 255 TYR A CZ  1 
ATOM   1592 O  OH  . TYR A 1 255 ? 177.366 145.259 165.888 1.00 130.46 ? 255 TYR A OH  1 
ATOM   1593 N  N   . VAL A 1 256 ? 173.874 145.726 173.960 1.00 124.80 ? 256 VAL A N   1 
ATOM   1594 C  CA  . VAL A 1 256 ? 173.090 145.387 175.141 1.00 124.80 ? 256 VAL A CA  1 
ATOM   1595 C  C   . VAL A 1 256 ? 172.402 146.614 175.723 1.00 124.80 ? 256 VAL A C   1 
ATOM   1596 O  O   . VAL A 1 256 ? 171.214 146.576 176.045 1.00 124.80 ? 256 VAL A O   1 
ATOM   1597 C  CB  . VAL A 1 256 ? 173.989 144.695 176.190 1.00 124.80 ? 256 VAL A CB  1 
ATOM   1598 C  CG1 . VAL A 1 256 ? 173.219 144.435 177.477 1.00 124.80 ? 256 VAL A CG1 1 
ATOM   1599 C  CG2 . VAL A 1 256 ? 174.560 143.401 175.629 1.00 124.80 ? 256 VAL A CG2 1 
ATOM   1600 N  N   . THR A 1 257 ? 173.131 147.725 175.842 1.00 121.07 ? 257 THR A N   1 
ATOM   1601 C  CA  . THR A 1 257 ? 172.633 148.927 176.500 1.00 121.07 ? 257 THR A CA  1 
ATOM   1602 C  C   . THR A 1 257 ? 171.897 149.866 175.552 1.00 121.07 ? 257 THR A C   1 
ATOM   1603 O  O   . THR A 1 257 ? 171.833 151.074 175.812 1.00 121.07 ? 257 THR A O   1 
ATOM   1604 C  CB  . THR A 1 257 ? 173.784 149.665 177.184 1.00 121.07 ? 257 THR A CB  1 
ATOM   1605 O  OG1 . THR A 1 257 ? 174.651 150.224 176.190 1.00 121.07 ? 257 THR A OG1 1 
ATOM   1606 C  CG2 . THR A 1 257 ? 174.576 148.710 178.064 1.00 121.07 ? 257 THR A CG2 1 
ATOM   1607 N  N   . ALA A 1 258 ? 171.351 149.354 174.464 1.00 114.12 ? 258 ALA A N   1 
ATOM   1608 C  CA  . ALA A 1 258 ? 170.516 150.173 173.593 1.00 114.12 ? 258 ALA A CA  1 
ATOM   1609 C  C   . ALA A 1 258 ? 169.129 149.588 173.392 1.00 114.12 ? 258 ALA A C   1 
ATOM   1610 O  O   . ALA A 1 258 ? 168.154 150.341 173.345 1.00 114.12 ? 258 ALA A O   1 
ATOM   1611 C  CB  . ALA A 1 258 ? 171.195 150.374 172.233 1.00 114.12 ? 258 ALA A CB  1 
ATOM   1612 N  N   . THR A 1 259 ? 169.014 148.267 173.267 1.00 106.54 ? 259 THR A N   1 
ATOM   1613 C  CA  . THR A 1 259 ? 167.711 147.626 173.157 1.00 106.54 ? 259 THR A CA  1 
ATOM   1614 C  C   . THR A 1 259 ? 167.100 147.299 174.512 1.00 106.54 ? 259 THR A C   1 
ATOM   1615 O  O   . THR A 1 259 ? 165.915 146.957 174.568 1.00 106.54 ? 259 THR A O   1 
ATOM   1616 C  CB  . THR A 1 259 ? 167.818 146.346 172.324 1.00 106.54 ? 259 THR A CB  1 
ATOM   1617 O  OG1 . THR A 1 259 ? 166.509 145.809 172.100 1.00 106.54 ? 259 THR A OG1 1 
ATOM   1618 C  CG2 . THR A 1 259 ? 168.670 145.309 173.041 1.00 106.54 ? 259 THR A CG2 1 
ATOM   1619 N  N   . PHE A 1 260 ? 167.879 147.391 175.590 1.00 101.04 ? 260 PHE A N   1 
ATOM   1620 C  CA  . PHE A 1 260 ? 167.360 147.110 176.929 1.00 101.04 ? 260 PHE A CA  1 
ATOM   1621 C  C   . PHE A 1 260 ? 166.247 148.056 177.382 1.00 101.04 ? 260 PHE A C   1 
ATOM   1622 O  O   . PHE A 1 260 ? 165.265 147.561 177.966 1.00 101.04 ? 260 PHE A O   1 
ATOM   1623 C  CB  . PHE A 1 260 ? 168.526 147.075 177.925 1.00 101.04 ? 260 PHE A CB  1 
ATOM   1624 C  CG  . PHE A 1 260 ? 168.105 146.835 179.343 1.00 101.04 ? 260 PHE A CG  1 
ATOM   1625 C  CD1 . PHE A 1 260 ? 167.628 145.597 179.737 1.00 101.04 ? 260 PHE A CD1 1 
ATOM   1626 C  CD2 . PHE A 1 260 ? 168.210 147.842 180.287 1.00 101.04 ? 260 PHE A CD2 1 
ATOM   1627 C  CE1 . PHE A 1 260 ? 167.244 145.373 181.045 1.00 101.04 ? 260 PHE A CE1 1 
ATOM   1628 C  CE2 . PHE A 1 260 ? 167.831 147.624 181.595 1.00 101.04 ? 260 PHE A CE2 1 
ATOM   1629 C  CZ  . PHE A 1 260 ? 167.347 146.387 181.975 1.00 101.04 ? 260 PHE A CZ  1 
ATOM   1630 N  N   . PRO A 1 261 ? 166.325 149.389 177.193 1.00 98.39  ? 261 PRO A N   1 
ATOM   1631 C  CA  . PRO A 1 261 ? 165.155 150.218 177.534 1.00 98.39  ? 261 PRO A CA  1 
ATOM   1632 C  C   . PRO A 1 261 ? 163.900 149.874 176.755 1.00 98.39  ? 261 PRO A C   1 
ATOM   1633 O  O   . PRO A 1 261 ? 162.805 149.938 177.323 1.00 98.39  ? 261 PRO A O   1 
ATOM   1634 C  CB  . PRO A 1 261 ? 165.633 151.642 177.226 1.00 98.39  ? 261 PRO A CB  1 
ATOM   1635 C  CG  . PRO A 1 261 ? 167.081 151.579 177.424 1.00 98.39  ? 261 PRO A CG  1 
ATOM   1636 C  CD  . PRO A 1 261 ? 167.470 150.258 176.851 1.00 98.39  ? 261 PRO A CD  1 
ATOM   1637 N  N   . TYR A 1 262 ? 164.019 149.478 175.487 1.00 100.17 ? 262 TYR A N   1 
ATOM   1638 C  CA  . TYR A 1 262 ? 162.827 149.124 174.723 1.00 100.17 ? 262 TYR A CA  1 
ATOM   1639 C  C   . TYR A 1 262 ? 162.235 147.801 175.191 1.00 100.17 ? 262 TYR A C   1 
ATOM   1640 O  O   . TYR A 1 262 ? 161.010 147.655 175.245 1.00 100.17 ? 262 TYR A O   1 
ATOM   1641 C  CB  . TYR A 1 262 ? 163.149 149.078 173.233 1.00 100.17 ? 262 TYR A CB  1 
ATOM   1642 C  CG  . TYR A 1 262 ? 163.668 150.390 172.711 1.00 100.17 ? 262 TYR A CG  1 
ATOM   1643 C  CD1 . TYR A 1 262 ? 162.809 151.458 172.494 1.00 100.17 ? 262 TYR A CD1 1 
ATOM   1644 C  CD2 . TYR A 1 262 ? 165.016 150.566 172.446 1.00 100.17 ? 262 TYR A CD2 1 
ATOM   1645 C  CE1 . TYR A 1 262 ? 163.278 152.663 172.022 1.00 100.17 ? 262 TYR A CE1 1 
ATOM   1646 C  CE2 . TYR A 1 262 ? 165.495 151.765 171.974 1.00 100.17 ? 262 TYR A CE2 1 
ATOM   1647 C  CZ  . TYR A 1 262 ? 164.623 152.810 171.763 1.00 100.17 ? 262 TYR A CZ  1 
ATOM   1648 O  OH  . TYR A 1 262 ? 165.103 154.007 171.291 1.00 100.17 ? 262 TYR A OH  1 
ATOM   1649 N  N   . ILE A 1 263 ? 163.086 146.833 175.545 1.00 96.10  ? 263 ILE A N   1 
ATOM   1650 C  CA  . ILE A 1 263 ? 162.598 145.571 176.100 1.00 96.10  ? 263 ILE A CA  1 
ATOM   1651 C  C   . ILE A 1 263 ? 161.890 145.810 177.427 1.00 96.10  ? 263 ILE A C   1 
ATOM   1652 O  O   . ILE A 1 263 ? 160.807 145.260 177.681 1.00 96.10  ? 263 ILE A O   1 
ATOM   1653 C  CB  . ILE A 1 263 ? 163.759 144.568 176.248 1.00 96.10  ? 263 ILE A CB  1 
ATOM   1654 C  CG1 . ILE A 1 263 ? 164.288 144.153 174.876 1.00 96.10  ? 263 ILE A CG1 1 
ATOM   1655 C  CG2 . ILE A 1 263 ? 163.331 143.343 177.041 1.00 96.10  ? 263 ILE A CG2 1 
ATOM   1656 C  CD1 . ILE A 1 263 ? 165.584 143.378 174.935 1.00 96.10  ? 263 ILE A CD1 1 
ATOM   1657 N  N   . MET A 1 264 ? 162.478 146.648 178.285 1.00 91.67  ? 264 MET A N   1 
ATOM   1658 C  CA  . MET A 1 264 ? 161.867 146.922 179.582 1.00 91.67  ? 264 MET A CA  1 
ATOM   1659 C  C   . MET A 1 264 ? 160.564 147.702 179.435 1.00 91.67  ? 264 MET A C   1 
ATOM   1660 O  O   . MET A 1 264 ? 159.588 147.425 180.143 1.00 91.67  ? 264 MET A O   1 
ATOM   1661 C  CB  . MET A 1 264 ? 162.853 147.670 180.473 1.00 91.67  ? 264 MET A CB  1 
ATOM   1662 C  CG  . MET A 1 264 ? 162.373 147.865 181.893 1.00 91.67  ? 264 MET A CG  1 
ATOM   1663 S  SD  . MET A 1 264 ? 162.076 146.288 182.705 1.00 91.67  ? 264 MET A SD  1 
ATOM   1664 C  CE  . MET A 1 264 ? 163.752 145.689 182.849 1.00 91.67  ? 264 MET A CE  1 
ATOM   1665 N  N   . LEU A 1 265 ? 160.518 148.664 178.510 1.00 89.46  ? 265 LEU A N   1 
ATOM   1666 C  CA  . LEU A 1 265 ? 159.277 149.389 178.254 1.00 89.46  ? 265 LEU A CA  1 
ATOM   1667 C  C   . LEU A 1 265 ? 158.206 148.469 177.685 1.00 89.46  ? 265 LEU A C   1 
ATOM   1668 O  O   . LEU A 1 265 ? 157.029 148.589 178.043 1.00 89.46  ? 265 LEU A O   1 
ATOM   1669 C  CB  . LEU A 1 265 ? 159.534 150.560 177.307 1.00 89.46  ? 265 LEU A CB  1 
ATOM   1670 C  CG  . LEU A 1 265 ? 159.776 151.920 177.961 1.00 89.46  ? 265 LEU A CG  1 
ATOM   1671 C  CD1 . LEU A 1 265 ? 159.731 153.027 176.923 1.00 89.46  ? 265 LEU A CD1 1 
ATOM   1672 C  CD2 . LEU A 1 265 ? 158.759 152.177 179.058 1.00 89.46  ? 265 LEU A CD2 1 
ATOM   1673 N  N   . LEU A 1 266 ? 158.595 147.541 176.806 1.00 92.22  ? 266 LEU A N   1 
ATOM   1674 C  CA  . LEU A 1 266 ? 157.638 146.603 176.233 1.00 92.22  ? 266 LEU A CA  1 
ATOM   1675 C  C   . LEU A 1 266 ? 157.059 145.682 177.299 1.00 92.22  ? 266 LEU A C   1 
ATOM   1676 O  O   . LEU A 1 266 ? 155.843 145.467 177.347 1.00 92.22  ? 266 LEU A O   1 
ATOM   1677 C  CB  . LEU A 1 266 ? 158.302 145.792 175.121 1.00 92.22  ? 266 LEU A CB  1 
ATOM   1678 C  CG  . LEU A 1 266 ? 157.493 144.620 174.565 1.00 92.22  ? 266 LEU A CG  1 
ATOM   1679 C  CD1 . LEU A 1 266 ? 156.347 145.125 173.704 1.00 92.22  ? 266 LEU A CD1 1 
ATOM   1680 C  CD2 . LEU A 1 266 ? 158.385 143.673 173.779 1.00 92.22  ? 266 LEU A CD2 1 
ATOM   1681 N  N   . ILE A 1 267 ? 157.911 145.144 178.179 1.00 91.28  ? 267 ILE A N   1 
ATOM   1682 C  CA  . ILE A 1 267 ? 157.396 144.240 179.206 1.00 91.28  ? 267 ILE A CA  1 
ATOM   1683 C  C   . ILE A 1 267 ? 156.578 145.008 180.244 1.00 91.28  ? 267 ILE A C   1 
ATOM   1684 O  O   . ILE A 1 267 ? 155.573 144.491 180.755 1.00 91.28  ? 267 ILE A O   1 
ATOM   1685 C  CB  . ILE A 1 267 ? 158.533 143.406 179.839 1.00 91.28  ? 267 ILE A CB  1 
ATOM   1686 C  CG1 . ILE A 1 267 ? 157.961 142.290 180.715 1.00 91.28  ? 267 ILE A CG1 1 
ATOM   1687 C  CG2 . ILE A 1 267 ? 159.494 144.248 180.650 1.00 91.28  ? 267 ILE A CG2 1 
ATOM   1688 C  CD1 . ILE A 1 267 ? 158.982 141.258 181.126 1.00 91.28  ? 267 ILE A CD1 1 
ATOM   1689 N  N   . LEU A 1 268 ? 156.939 146.266 180.526 1.00 89.17  ? 268 LEU A N   1 
ATOM   1690 C  CA  . LEU A 1 268 ? 156.150 147.060 181.461 1.00 89.17  ? 268 LEU A CA  1 
ATOM   1691 C  C   . LEU A 1 268 ? 154.791 147.421 180.872 1.00 89.17  ? 268 LEU A C   1 
ATOM   1692 O  O   . LEU A 1 268 ? 153.785 147.415 181.586 1.00 89.17  ? 268 LEU A O   1 
ATOM   1693 C  CB  . LEU A 1 268 ? 156.916 148.319 181.863 1.00 89.17  ? 268 LEU A CB  1 
ATOM   1694 C  CG  . LEU A 1 268 ? 157.911 148.138 183.011 1.00 89.17  ? 268 LEU A CG  1 
ATOM   1695 C  CD1 . LEU A 1 268 ? 158.679 149.423 183.264 1.00 89.17  ? 268 LEU A CD1 1 
ATOM   1696 C  CD2 . LEU A 1 268 ? 157.205 147.672 184.273 1.00 89.17  ? 268 LEU A CD2 1 
ATOM   1697 N  N   . LEU A 1 269 ? 154.738 147.720 179.571 1.00 88.39  ? 269 LEU A N   1 
ATOM   1698 C  CA  . LEU A 1 269 ? 153.460 147.984 178.917 1.00 88.39  ? 269 LEU A CA  1 
ATOM   1699 C  C   . LEU A 1 269 ? 152.599 146.726 178.865 1.00 88.39  ? 269 LEU A C   1 
ATOM   1700 O  O   . LEU A 1 269 ? 151.379 146.791 179.079 1.00 88.39  ? 269 LEU A O   1 
ATOM   1701 C  CB  . LEU A 1 269 ? 153.704 148.529 177.509 1.00 88.39  ? 269 LEU A CB  1 
ATOM   1702 C  CG  . LEU A 1 269 ? 152.523 148.595 176.539 1.00 88.39  ? 269 LEU A CG  1 
ATOM   1703 C  CD1 . LEU A 1 269 ? 151.426 149.496 177.078 1.00 88.39  ? 269 LEU A CD1 1 
ATOM   1704 C  CD2 . LEU A 1 269 ? 152.970 149.055 175.165 1.00 88.39  ? 269 LEU A CD2 1 
ATOM   1705 N  N   . ILE A 1 270 ? 153.226 145.577 178.588 1.00 90.03  ? 270 ILE A N   1 
ATOM   1706 C  CA  . ILE A 1 270 ? 152.519 144.299 178.542 1.00 90.03  ? 270 ILE A CA  1 
ATOM   1707 C  C   . ILE A 1 270 ? 151.907 143.982 179.900 1.00 90.03  ? 270 ILE A C   1 
ATOM   1708 O  O   . ILE A 1 270 ? 150.762 143.518 179.989 1.00 90.03  ? 270 ILE A O   1 
ATOM   1709 C  CB  . ILE A 1 270 ? 153.476 143.187 178.063 1.00 90.03  ? 270 ILE A CB  1 
ATOM   1710 C  CG1 . ILE A 1 270 ? 153.621 143.226 176.539 1.00 90.03  ? 270 ILE A CG1 1 
ATOM   1711 C  CG2 . ILE A 1 270 ? 153.018 141.805 178.514 1.00 90.03  ? 270 ILE A CG2 1 
ATOM   1712 C  CD1 . ILE A 1 270 ? 152.331 142.976 175.792 1.00 90.03  ? 270 ILE A CD1 1 
ATOM   1713 N  N   . ARG A 1 271 ? 152.646 144.248 180.980 1.00 90.86  ? 271 ARG A N   1 
ATOM   1714 C  CA  . ARG A 1 271 ? 152.061 144.090 182.307 1.00 90.86  ? 271 ARG A CA  1 
ATOM   1715 C  C   . ARG A 1 271 ? 150.959 145.115 182.553 1.00 90.86  ? 271 ARG A C   1 
ATOM   1716 O  O   . ARG A 1 271 ? 149.875 144.755 183.019 1.00 90.86  ? 271 ARG A O   1 
ATOM   1717 C  CB  . ARG A 1 271 ? 153.136 144.194 183.386 1.00 90.86  ? 271 ARG A CB  1 
ATOM   1718 C  CG  . ARG A 1 271 ? 152.593 144.121 184.808 1.00 90.86  ? 271 ARG A CG  1 
ATOM   1719 C  CD  . ARG A 1 271 ? 151.768 142.855 185.032 1.00 90.86  ? 271 ARG A CD  1 
ATOM   1720 N  NE  . ARG A 1 271 ? 152.530 141.636 184.790 1.00 90.86  ? 271 ARG A NE  1 
ATOM   1721 C  CZ  . ARG A 1 271 ? 152.051 140.409 184.946 1.00 90.86  ? 271 ARG A CZ  1 
ATOM   1722 N  NH1 . ARG A 1 271 ? 150.815 140.198 185.368 1.00 90.86  ? 271 ARG A NH1 1 
ATOM   1723 N  NH2 . ARG A 1 271 ? 152.830 139.367 184.669 1.00 90.86  ? 271 ARG A NH2 1 
ATOM   1724 N  N   . GLY A 1 272 ? 151.204 146.382 182.204 1.00 89.42  ? 272 GLY A N   1 
ATOM   1725 C  CA  . GLY A 1 272 ? 150.285 147.449 182.574 1.00 89.42  ? 272 GLY A CA  1 
ATOM   1726 C  C   . GLY A 1 272 ? 148.922 147.334 181.919 1.00 89.42  ? 272 GLY A C   1 
ATOM   1727 O  O   . GLY A 1 272 ? 147.906 147.680 182.524 1.00 89.42  ? 272 GLY A O   1 
ATOM   1728 N  N   . VAL A 1 273 ? 148.876 146.837 180.680 1.00 88.61  ? 273 VAL A N   1 
ATOM   1729 C  CA  . VAL A 1 273 ? 147.574 146.625 180.057 1.00 88.61  ? 273 VAL A CA  1 
ATOM   1730 C  C   . VAL A 1 273 ? 146.839 145.436 180.668 1.00 88.61  ? 273 VAL A C   1 
ATOM   1731 O  O   . VAL A 1 273 ? 145.618 145.326 180.519 1.00 88.61  ? 273 VAL A O   1 
ATOM   1732 C  CB  . VAL A 1 273 ? 147.714 146.448 178.534 1.00 88.61  ? 273 VAL A CB  1 
ATOM   1733 C  CG1 . VAL A 1 273 ? 148.257 147.717 177.904 1.00 88.61  ? 273 VAL A CG1 1 
ATOM   1734 C  CG2 . VAL A 1 273 ? 148.597 145.257 178.210 1.00 88.61  ? 273 VAL A CG2 1 
ATOM   1735 N  N   . THR A 1 274 ? 147.549 144.546 181.364 1.00 88.01  ? 274 THR A N   1 
ATOM   1736 C  CA  . THR A 1 274 ? 146.932 143.371 181.967 1.00 88.01  ? 274 THR A CA  1 
ATOM   1737 C  C   . THR A 1 274 ? 146.309 143.682 183.328 1.00 88.01  ? 274 THR A C   1 
ATOM   1738 O  O   . THR A 1 274 ? 145.379 142.980 183.746 1.00 88.01  ? 274 THR A O   1 
ATOM   1739 C  CB  . THR A 1 274 ? 147.986 142.259 182.074 1.00 88.01  ? 274 THR A CB  1 
ATOM   1740 O  OG1 . THR A 1 274 ? 148.600 142.074 180.793 1.00 88.01  ? 274 THR A OG1 1 
ATOM   1741 C  CG2 . THR A 1 274 ? 147.377 140.923 182.489 1.00 88.01  ? 274 THR A CG2 1 
ATOM   1742 N  N   . LEU A 1 275 ? 146.776 144.735 184.002 1.00 87.01  ? 275 LEU A N   1 
ATOM   1743 C  CA  . LEU A 1 275 ? 146.235 145.132 185.300 1.00 87.01  ? 275 LEU A CA  1 
ATOM   1744 C  C   . LEU A 1 275 ? 144.753 145.483 185.201 1.00 87.01  ? 275 LEU A C   1 
ATOM   1745 O  O   . LEU A 1 275 ? 144.347 146.176 184.259 1.00 87.01  ? 275 LEU A O   1 
ATOM   1746 C  CB  . LEU A 1 275 ? 147.021 146.323 185.856 1.00 87.01  ? 275 LEU A CB  1 
ATOM   1747 C  CG  . LEU A 1 275 ? 148.238 146.085 186.758 1.00 87.01  ? 275 LEU A CG  1 
ATOM   1748 C  CD1 . LEU A 1 275 ? 149.345 145.368 186.069 1.00 87.01  ? 275 LEU A CD1 1 
ATOM   1749 C  CD2 . LEU A 1 275 ? 148.783 147.417 187.215 1.00 87.01  ? 275 LEU A CD2 1 
ATOM   1750 N  N   . PRO A 1 276 ? 143.919 145.004 186.124 1.00 84.27  ? 276 PRO A N   1 
ATOM   1751 C  CA  . PRO A 1 276 ? 142.488 145.317 186.069 1.00 84.27  ? 276 PRO A CA  1 
ATOM   1752 C  C   . PRO A 1 276 ? 142.231 146.790 186.325 1.00 84.27  ? 276 PRO A C   1 
ATOM   1753 O  O   . PRO A 1 276 ? 142.967 147.457 187.053 1.00 84.27  ? 276 PRO A O   1 
ATOM   1754 C  CB  . PRO A 1 276 ? 141.887 144.451 187.184 1.00 84.27  ? 276 PRO A CB  1 
ATOM   1755 C  CG  . PRO A 1 276 ? 142.949 143.457 187.539 1.00 84.27  ? 276 PRO A CG  1 
ATOM   1756 C  CD  . PRO A 1 276 ? 144.250 144.121 187.252 1.00 84.27  ? 276 PRO A CD  1 
ATOM   1757 N  N   . GLY A 1 277 ? 141.166 147.299 185.713 1.00 83.84  ? 277 GLY A N   1 
ATOM   1758 C  CA  . GLY A 1 277 ? 140.877 148.713 185.818 1.00 83.84  ? 277 GLY A CA  1 
ATOM   1759 C  C   . GLY A 1 277 ? 141.749 149.604 184.967 1.00 83.84  ? 277 GLY A C   1 
ATOM   1760 O  O   . GLY A 1 277 ? 141.742 150.822 185.164 1.00 83.84  ? 277 GLY A O   1 
ATOM   1761 N  N   . ALA A 1 278 ? 142.509 149.036 184.032 1.00 82.07  ? 278 ALA A N   1 
ATOM   1762 C  CA  . ALA A 1 278 ? 143.307 149.835 183.113 1.00 82.07  ? 278 ALA A CA  1 
ATOM   1763 C  C   . ALA A 1 278 ? 142.481 150.432 181.986 1.00 82.07  ? 278 ALA A C   1 
ATOM   1764 O  O   . ALA A 1 278 ? 142.963 151.345 181.307 1.00 82.07  ? 278 ALA A O   1 
ATOM   1765 C  CB  . ALA A 1 278 ? 144.437 148.993 182.521 1.00 82.07  ? 278 ALA A CB  1 
ATOM   1766 N  N   . SER A 1 279 ? 141.261 149.935 181.768 1.00 83.23  ? 279 SER A N   1 
ATOM   1767 C  CA  . SER A 1 279 ? 140.389 150.526 180.760 1.00 83.23  ? 279 SER A CA  1 
ATOM   1768 C  C   . SER A 1 279 ? 140.006 151.950 181.136 1.00 83.23  ? 279 SER A C   1 
ATOM   1769 O  O   . SER A 1 279 ? 139.998 152.843 180.281 1.00 83.23  ? 279 SER A O   1 
ATOM   1770 C  CB  . SER A 1 279 ? 139.141 149.665 180.576 1.00 83.23  ? 279 SER A CB  1 
ATOM   1771 O  OG  . SER A 1 279 ? 139.488 148.328 180.264 1.00 83.23  ? 279 SER A OG  1 
ATOM   1772 N  N   . GLU A 1 280 ? 139.701 152.182 182.416 1.00 83.14  ? 280 GLU A N   1 
ATOM   1773 C  CA  . GLU A 1 280 ? 139.398 153.532 182.881 1.00 83.14  ? 280 GLU A CA  1 
ATOM   1774 C  C   . GLU A 1 280 ? 140.615 154.440 182.769 1.00 83.14  ? 280 GLU A C   1 
ATOM   1775 O  O   . GLU A 1 280 ? 140.489 155.617 182.412 1.00 83.14  ? 280 GLU A O   1 
ATOM   1776 C  CB  . GLU A 1 280 ? 138.893 153.491 184.321 1.00 83.14  ? 280 GLU A CB  1 
ATOM   1777 C  CG  . GLU A 1 280 ? 137.607 152.708 184.505 1.00 83.14  ? 280 GLU A CG  1 
ATOM   1778 C  CD  . GLU A 1 280 ? 136.629 152.919 183.367 1.00 83.14  ? 280 GLU A CD  1 
ATOM   1779 O  OE1 . GLU A 1 280 ? 136.056 154.025 183.274 1.00 83.14  ? 280 GLU A OE1 1 
ATOM   1780 O  OE2 . GLU A 1 280 ? 136.433 151.981 182.567 1.00 83.14  ? 280 GLU A OE2 1 
ATOM   1781 N  N   . GLY A 1 281 ? 141.802 153.907 183.064 1.00 77.50  ? 281 GLY A N   1 
ATOM   1782 C  CA  . GLY A 1 281 ? 143.014 154.696 182.922 1.00 77.50  ? 281 GLY A CA  1 
ATOM   1783 C  C   . GLY A 1 281 ? 143.296 155.084 181.485 1.00 77.50  ? 281 GLY A C   1 
ATOM   1784 O  O   . GLY A 1 281 ? 143.656 156.228 181.205 1.00 77.50  ? 281 GLY A O   1 
ATOM   1785 N  N   . ILE A 1 282 ? 143.110 154.148 180.551 1.00 77.78  ? 282 ILE A N   1 
ATOM   1786 C  CA  . ILE A 1 282 ? 143.332 154.450 179.139 1.00 77.78  ? 282 ILE A CA  1 
ATOM   1787 C  C   . ILE A 1 282 ? 142.270 155.417 178.619 1.00 77.78  ? 282 ILE A C   1 
ATOM   1788 O  O   . ILE A 1 282 ? 142.572 156.319 177.827 1.00 77.78  ? 282 ILE A O   1 
ATOM   1789 C  CB  . ILE A 1 282 ? 143.391 153.144 178.325 1.00 77.78  ? 282 ILE A CB  1 
ATOM   1790 C  CG1 . ILE A 1 282 ? 144.669 152.376 178.662 1.00 77.78  ? 282 ILE A CG1 1 
ATOM   1791 C  CG2 . ILE A 1 282 ? 143.348 153.407 176.832 1.00 77.78  ? 282 ILE A CG2 1 
ATOM   1792 C  CD1 . ILE A 1 282 ? 144.763 151.028 177.995 1.00 77.78  ? 282 ILE A CD1 1 
ATOM   1793 N  N   . LYS A 1 283 ? 141.021 155.267 179.075 1.00 79.56  ? 283 LYS A N   1 
ATOM   1794 C  CA  . LYS A 1 283 ? 139.963 156.195 178.680 1.00 79.56  ? 283 LYS A CA  1 
ATOM   1795 C  C   . LYS A 1 283 ? 140.243 157.607 179.185 1.00 79.56  ? 283 LYS A C   1 
ATOM   1796 O  O   . LYS A 1 283 ? 140.055 158.584 178.451 1.00 79.56  ? 283 LYS A O   1 
ATOM   1797 C  CB  . LYS A 1 283 ? 138.613 155.689 179.192 1.00 79.56  ? 283 LYS A CB  1 
ATOM   1798 C  CG  . LYS A 1 283 ? 137.553 156.765 179.377 1.00 79.56  ? 283 LYS A CG  1 
ATOM   1799 C  CD  . LYS A 1 283 ? 136.153 156.211 179.168 1.00 79.56  ? 283 LYS A CD  1 
ATOM   1800 C  CE  . LYS A 1 283 ? 135.888 155.004 180.051 1.00 79.56  ? 283 LYS A CE  1 
ATOM   1801 N  NZ  . LYS A 1 283 ? 134.513 154.470 179.854 1.00 79.56  ? 283 LYS A NZ  1 
ATOM   1802 N  N   . PHE A 1 284 ? 140.708 157.733 180.430 1.00 76.54  ? 284 PHE A N   1 
ATOM   1803 C  CA  . PHE A 1 284 ? 141.142 159.029 180.944 1.00 76.54  ? 284 PHE A CA  1 
ATOM   1804 C  C   . PHE A 1 284 ? 142.349 159.554 180.177 1.00 76.54  ? 284 PHE A C   1 
ATOM   1805 O  O   . PHE A 1 284 ? 142.484 160.767 179.981 1.00 76.54  ? 284 PHE A O   1 
ATOM   1806 C  CB  . PHE A 1 284 ? 141.455 158.903 182.437 1.00 76.54  ? 284 PHE A CB  1 
ATOM   1807 C  CG  . PHE A 1 284 ? 142.162 160.091 183.025 1.00 76.54  ? 284 PHE A CG  1 
ATOM   1808 C  CD1 . PHE A 1 284 ? 141.462 161.240 183.344 1.00 76.54  ? 284 PHE A CD1 1 
ATOM   1809 C  CD2 . PHE A 1 284 ? 143.522 160.047 183.290 1.00 76.54  ? 284 PHE A CD2 1 
ATOM   1810 C  CE1 . PHE A 1 284 ? 142.106 162.329 183.893 1.00 76.54  ? 284 PHE A CE1 1 
ATOM   1811 C  CE2 . PHE A 1 284 ? 144.168 161.131 183.839 1.00 76.54  ? 284 PHE A CE2 1 
ATOM   1812 C  CZ  . PHE A 1 284 ? 143.461 162.272 184.143 1.00 76.54  ? 284 PHE A CZ  1 
ATOM   1813 N  N   . TYR A 1 285 ? 143.228 158.656 179.736 1.00 73.76  ? 285 TYR A N   1 
ATOM   1814 C  CA  . TYR A 1 285 ? 144.426 159.053 179.010 1.00 73.76  ? 285 TYR A CA  1 
ATOM   1815 C  C   . TYR A 1 285 ? 144.104 159.553 177.609 1.00 73.76  ? 285 TYR A C   1 
ATOM   1816 O  O   . TYR A 1 285 ? 144.836 160.389 177.072 1.00 73.76  ? 285 TYR A O   1 
ATOM   1817 C  CB  . TYR A 1 285 ? 145.389 157.868 178.957 1.00 73.76  ? 285 TYR A CB  1 
ATOM   1818 C  CG  . TYR A 1 285 ? 146.663 158.093 178.181 1.00 73.76  ? 285 TYR A CG  1 
ATOM   1819 C  CD1 . TYR A 1 285 ? 147.463 159.198 178.425 1.00 73.76  ? 285 TYR A CD1 1 
ATOM   1820 C  CD2 . TYR A 1 285 ? 147.083 157.179 177.228 1.00 73.76  ? 285 TYR A CD2 1 
ATOM   1821 C  CE1 . TYR A 1 285 ? 148.635 159.398 177.723 1.00 73.76  ? 285 TYR A CE1 1 
ATOM   1822 C  CE2 . TYR A 1 285 ? 148.253 157.369 176.523 1.00 73.76  ? 285 TYR A CE2 1 
ATOM   1823 C  CZ  . TYR A 1 285 ? 149.024 158.479 176.775 1.00 73.76  ? 285 TYR A CZ  1 
ATOM   1824 O  OH  . TYR A 1 285 ? 150.191 158.674 176.076 1.00 73.76  ? 285 TYR A OH  1 
ATOM   1825 N  N   . LEU A 1 286 ? 143.018 159.068 177.005 1.00 78.50  ? 286 LEU A N   1 
ATOM   1826 C  CA  . LEU A 1 286 ? 142.733 159.347 175.602 1.00 78.50  ? 286 LEU A CA  1 
ATOM   1827 C  C   . LEU A 1 286 ? 141.550 160.288 175.393 1.00 78.50  ? 286 LEU A C   1 
ATOM   1828 O  O   . LEU A 1 286 ? 141.630 161.192 174.558 1.00 78.50  ? 286 LEU A O   1 
ATOM   1829 C  CB  . LEU A 1 286 ? 142.496 158.031 174.851 1.00 78.50  ? 286 LEU A CB  1 
ATOM   1830 C  CG  . LEU A 1 286 ? 143.773 157.243 174.554 1.00 78.50  ? 286 LEU A CG  1 
ATOM   1831 C  CD1 . LEU A 1 286 ? 143.451 155.870 173.996 1.00 78.50  ? 286 LEU A CD1 1 
ATOM   1832 C  CD2 . LEU A 1 286 ? 144.666 158.015 173.599 1.00 78.50  ? 286 LEU A CD2 1 
ATOM   1833 N  N   . TYR A 1 287 ? 140.457 160.101 176.123 1.00 87.26  ? 287 TYR A N   1 
ATOM   1834 C  CA  . TYR A 1 287 ? 139.272 160.932 175.915 1.00 87.26  ? 287 TYR A CA  1 
ATOM   1835 C  C   . TYR A 1 287 ? 139.500 162.321 176.503 1.00 87.26  ? 287 TYR A C   1 
ATOM   1836 O  O   . TYR A 1 287 ? 139.750 162.440 177.709 1.00 87.26  ? 287 TYR A O   1 
ATOM   1837 C  CB  . TYR A 1 287 ? 138.045 160.271 176.542 1.00 87.26  ? 287 TYR A CB  1 
ATOM   1838 C  CG  . TYR A 1 287 ? 136.723 160.916 176.180 1.00 87.26  ? 287 TYR A CG  1 
ATOM   1839 C  CD1 . TYR A 1 287 ? 136.178 161.927 176.965 1.00 87.26  ? 287 TYR A CD1 1 
ATOM   1840 C  CD2 . TYR A 1 287 ? 136.016 160.506 175.056 1.00 87.26  ? 287 TYR A CD2 1 
ATOM   1841 C  CE1 . TYR A 1 287 ? 134.970 162.516 176.636 1.00 87.26  ? 287 TYR A CE1 1 
ATOM   1842 C  CE2 . TYR A 1 287 ? 134.807 161.088 174.719 1.00 87.26  ? 287 TYR A CE2 1 
ATOM   1843 C  CZ  . TYR A 1 287 ? 134.290 162.092 175.513 1.00 87.26  ? 287 TYR A CZ  1 
ATOM   1844 O  OH  . TYR A 1 287 ? 133.088 162.675 175.183 1.00 87.26  ? 287 TYR A OH  1 
ATOM   1845 N  N   . PRO A 1 288 ? 139.426 163.383 175.706 1.00 85.88  ? 288 PRO A N   1 
ATOM   1846 C  CA  . PRO A 1 288 ? 139.774 164.720 176.191 1.00 85.88  ? 288 PRO A CA  1 
ATOM   1847 C  C   . PRO A 1 288 ? 138.575 165.531 176.668 1.00 85.88  ? 288 PRO A C   1 
ATOM   1848 O  O   . PRO A 1 288 ? 137.417 165.227 176.376 1.00 85.88  ? 288 PRO A O   1 
ATOM   1849 C  CB  . PRO A 1 288 ? 140.395 165.368 174.948 1.00 85.88  ? 288 PRO A CB  1 
ATOM   1850 C  CG  . PRO A 1 288 ? 139.647 164.736 173.807 1.00 85.88  ? 288 PRO A CG  1 
ATOM   1851 C  CD  . PRO A 1 288 ? 139.167 163.375 174.257 1.00 85.88  ? 288 PRO A CD  1 
ATOM   1852 N  N   . ASP A 1 289 ? 138.886 166.588 177.418 1.00 89.14  ? 289 ASP A N   1 
ATOM   1853 C  CA  . ASP A 1 289 ? 137.921 167.604 177.825 1.00 89.14  ? 289 ASP A CA  1 
ATOM   1854 C  C   . ASP A 1 289 ? 138.332 168.953 177.249 1.00 89.14  ? 289 ASP A C   1 
ATOM   1855 O  O   . ASP A 1 289 ? 139.499 169.344 177.349 1.00 89.14  ? 289 ASP A O   1 
ATOM   1856 C  CB  . ASP A 1 289 ? 137.818 167.709 179.350 1.00 89.14  ? 289 ASP A CB  1 
ATOM   1857 C  CG  . ASP A 1 289 ? 137.340 166.428 180.001 1.00 89.14  ? 289 ASP A CG  1 
ATOM   1858 O  OD1 . ASP A 1 289 ? 137.008 165.466 179.280 1.00 89.14  ? 289 ASP A OD1 1 
ATOM   1859 O  OD2 . ASP A 1 289 ? 137.289 166.386 181.248 1.00 89.14  ? 289 ASP A OD2 1 
ATOM   1860 N  N   . LEU A 1 290 ? 137.370 169.665 176.658 1.00 90.04  ? 290 LEU A N   1 
ATOM   1861 C  CA  . LEU A 1 290 ? 137.659 170.984 176.099 1.00 90.04  ? 290 LEU A CA  1 
ATOM   1862 C  C   . LEU A 1 290 ? 137.814 172.035 177.192 1.00 90.04  ? 290 LEU A C   1 
ATOM   1863 O  O   . LEU A 1 290 ? 138.567 173.006 177.021 1.00 90.04  ? 290 LEU A O   1 
ATOM   1864 C  CB  . LEU A 1 290 ? 136.559 171.397 175.118 1.00 90.04  ? 290 LEU A CB  1 
ATOM   1865 C  CG  . LEU A 1 290 ? 136.624 170.944 173.651 1.00 90.04  ? 290 LEU A CG  1 
ATOM   1866 C  CD1 . LEU A 1 290 ? 137.857 171.517 172.966 1.00 90.04  ? 290 LEU A CD1 1 
ATOM   1867 C  CD2 . LEU A 1 290 ? 136.564 169.426 173.478 1.00 90.04  ? 290 LEU A CD2 1 
ATOM   1868 N  N   . SER A 1 291 ? 137.105 171.864 178.313 1.00 88.83  ? 291 SER A N   1 
ATOM   1869 C  CA  . SER A 1 291 ? 137.265 172.769 179.446 1.00 88.83  ? 291 SER A CA  1 
ATOM   1870 C  C   . SER A 1 291 ? 138.678 172.705 180.008 1.00 88.83  ? 291 SER A C   1 
ATOM   1871 O  O   . SER A 1 291 ? 139.205 173.718 180.483 1.00 88.83  ? 291 SER A O   1 
ATOM   1872 C  CB  . SER A 1 291 ? 136.244 172.435 180.533 1.00 88.83  ? 291 SER A CB  1 
ATOM   1873 O  OG  . SER A 1 291 ? 134.920 172.609 180.060 1.00 88.83  ? 291 SER A OG  1 
ATOM   1874 N  N   . ARG A 1 292 ? 139.305 171.532 179.958 1.00 87.18  ? 292 ARG A N   1 
ATOM   1875 C  CA  . ARG A 1 292 ? 140.715 171.404 180.289 1.00 87.18  ? 292 ARG A CA  1 
ATOM   1876 C  C   . ARG A 1 292 ? 141.627 171.908 179.180 1.00 87.18  ? 292 ARG A C   1 
ATOM   1877 O  O   . ARG A 1 292 ? 142.816 172.115 179.431 1.00 87.18  ? 292 ARG A O   1 
ATOM   1878 C  CB  . ARG A 1 292 ? 141.052 169.948 180.617 1.00 87.18  ? 292 ARG A CB  1 
ATOM   1879 C  CG  . ARG A 1 292 ? 140.434 169.455 181.912 1.00 87.18  ? 292 ARG A CG  1 
ATOM   1880 C  CD  . ARG A 1 292 ? 140.980 170.237 183.094 1.00 87.18  ? 292 ARG A CD  1 
ATOM   1881 N  NE  . ARG A 1 292 ? 142.418 170.054 183.244 1.00 87.18  ? 292 ARG A NE  1 
ATOM   1882 C  CZ  . ARG A 1 292 ? 143.208 170.862 183.938 1.00 87.18  ? 292 ARG A CZ  1 
ATOM   1883 N  NH1 . ARG A 1 292 ? 142.730 171.926 184.561 1.00 87.18  ? 292 ARG A NH1 1 
ATOM   1884 N  NH2 . ARG A 1 292 ? 144.509 170.597 184.005 1.00 87.18  ? 292 ARG A NH2 1 
ATOM   1885 N  N   . LEU A 1 293 ? 141.111 172.095 177.965 1.00 84.74  ? 293 LEU A N   1 
ATOM   1886 C  CA  . LEU A 1 293 ? 141.857 172.753 176.902 1.00 84.74  ? 293 LEU A CA  1 
ATOM   1887 C  C   . LEU A 1 293 ? 141.751 174.269 176.955 1.00 84.74  ? 293 LEU A C   1 
ATOM   1888 O  O   . LEU A 1 293 ? 142.520 174.951 176.270 1.00 84.74  ? 293 LEU A O   1 
ATOM   1889 C  CB  . LEU A 1 293 ? 141.381 172.268 175.528 1.00 84.74  ? 293 LEU A CB  1 
ATOM   1890 C  CG  . LEU A 1 293 ? 142.152 171.105 174.914 1.00 84.74  ? 293 LEU A CG  1 
ATOM   1891 C  CD1 . LEU A 1 293 ? 141.430 170.583 173.692 1.00 84.74  ? 293 LEU A CD1 1 
ATOM   1892 C  CD2 . LEU A 1 293 ? 143.545 171.569 174.550 1.00 84.74  ? 293 LEU A CD2 1 
ATOM   1893 N  N   . SER A 1 294 ? 140.816 174.804 177.741 1.00 86.09  ? 294 SER A N   1 
ATOM   1894 C  CA  . SER A 1 294 ? 140.623 176.248 177.822 1.00 86.09  ? 294 SER A CA  1 
ATOM   1895 C  C   . SER A 1 294 ? 141.804 176.988 178.442 1.00 86.09  ? 294 SER A C   1 
ATOM   1896 O  O   . SER A 1 294 ? 142.003 178.165 178.123 1.00 86.09  ? 294 SER A O   1 
ATOM   1897 C  CB  . SER A 1 294 ? 139.355 176.561 178.618 1.00 86.09  ? 294 SER A CB  1 
ATOM   1898 O  OG  . SER A 1 294 ? 138.244 175.840 178.115 1.00 86.09  ? 294 SER A OG  1 
ATOM   1899 N  N   . ASP A 1 295 ? 142.599 176.335 179.315 1.00 85.67  ? 295 ASP A N   1 
ATOM   1900 C  CA  . ASP A 1 295 ? 143.667 177.106 179.938 1.00 85.67  ? 295 ASP A CA  1 
ATOM   1901 C  C   . ASP A 1 295 ? 144.943 177.050 179.100 1.00 85.67  ? 295 ASP A C   1 
ATOM   1902 O  O   . ASP A 1 295 ? 145.136 176.118 178.315 1.00 85.67  ? 295 ASP A O   1 
ATOM   1903 C  CB  . ASP A 1 295 ? 143.944 176.601 181.364 1.00 85.67  ? 295 ASP A CB  1 
ATOM   1904 C  CG  . ASP A 1 295 ? 144.257 175.115 181.426 1.00 85.67  ? 295 ASP A CG  1 
ATOM   1905 O  OD1 . ASP A 1 295 ? 144.172 174.425 180.392 1.00 85.67  ? 295 ASP A OD1 1 
ATOM   1906 O  OD2 . ASP A 1 295 ? 144.595 174.635 182.529 1.00 85.67  ? 295 ASP A OD2 1 
ATOM   1907 N  N   . PRO A 1 296 ? 145.831 178.047 179.210 1.00 80.08  ? 296 PRO A N   1 
ATOM   1908 C  CA  . PRO A 1 296 ? 147.064 178.012 178.409 1.00 80.08  ? 296 PRO A CA  1 
ATOM   1909 C  C   . PRO A 1 296 ? 148.140 177.094 178.953 1.00 80.08  ? 296 PRO A C   1 
ATOM   1910 O  O   . PRO A 1 296 ? 149.151 176.889 178.262 1.00 80.08  ? 296 PRO A O   1 
ATOM   1911 C  CB  . PRO A 1 296 ? 147.536 179.467 178.440 1.00 80.08  ? 296 PRO A CB  1 
ATOM   1912 C  CG  . PRO A 1 296 ? 147.022 179.977 179.724 1.00 80.08  ? 296 PRO A CG  1 
ATOM   1913 C  CD  . PRO A 1 296 ? 145.679 179.337 179.904 1.00 80.08  ? 296 PRO A CD  1 
ATOM   1914 N  N   . GLN A 1 297 ? 147.966 176.554 180.162 1.00 79.01  ? 297 GLN A N   1 
ATOM   1915 C  CA  . GLN A 1 297 ? 148.979 175.680 180.745 1.00 79.01  ? 297 GLN A CA  1 
ATOM   1916 C  C   . GLN A 1 297 ? 149.165 174.417 179.918 1.00 79.01  ? 297 GLN A C   1 
ATOM   1917 O  O   . GLN A 1 297 ? 150.298 173.963 179.717 1.00 79.01  ? 297 GLN A O   1 
ATOM   1918 C  CB  . GLN A 1 297 ? 148.602 175.324 182.182 1.00 79.01  ? 297 GLN A CB  1 
ATOM   1919 C  CG  . GLN A 1 297 ? 149.291 176.176 183.227 1.00 79.01  ? 297 GLN A CG  1 
ATOM   1920 C  CD  . GLN A 1 297 ? 150.785 175.936 183.267 1.00 79.01  ? 297 GLN A CD  1 
ATOM   1921 O  OE1 . GLN A 1 297 ? 151.570 176.761 182.804 1.00 79.01  ? 297 GLN A OE1 1 
ATOM   1922 N  NE2 . GLN A 1 297 ? 151.185 174.795 183.814 1.00 79.01  ? 297 GLN A NE2 1 
ATOM   1923 N  N   . VAL A 1 298 ? 148.066 173.848 179.417 1.00 75.32  ? 298 VAL A N   1 
ATOM   1924 C  CA  . VAL A 1 298 ? 148.142 172.631 178.615 1.00 75.32  ? 298 VAL A CA  1 
ATOM   1925 C  C   . VAL A 1 298 ? 148.897 172.888 177.319 1.00 75.32  ? 298 VAL A C   1 
ATOM   1926 O  O   . VAL A 1 298 ? 149.762 172.097 176.923 1.00 75.32  ? 298 VAL A O   1 
ATOM   1927 C  CB  . VAL A 1 298 ? 146.728 172.087 178.351 1.00 75.32  ? 298 VAL A CB  1 
ATOM   1928 C  CG1 . VAL A 1 298 ? 146.787 170.855 177.472 1.00 75.32  ? 298 VAL A CG1 1 
ATOM   1929 C  CG2 . VAL A 1 298 ? 146.044 171.770 179.659 1.00 75.32  ? 298 VAL A CG2 1 
ATOM   1930 N  N   . TRP A 1 299 ? 148.605 174.010 176.658 1.00 77.28  ? 299 TRP A N   1 
ATOM   1931 C  CA  . TRP A 1 299 ? 149.274 174.345 175.403 1.00 77.28  ? 299 TRP A CA  1 
ATOM   1932 C  C   . TRP A 1 299 ? 150.761 174.603 175.617 1.00 77.28  ? 299 TRP A C   1 
ATOM   1933 O  O   . TRP A 1 299 ? 151.604 174.111 174.853 1.00 77.28  ? 299 TRP A O   1 
ATOM   1934 C  CB  . TRP A 1 299 ? 148.601 175.562 174.771 1.00 77.28  ? 299 TRP A CB  1 
ATOM   1935 C  CG  . TRP A 1 299 ? 147.173 175.323 174.419 1.00 77.28  ? 299 TRP A CG  1 
ATOM   1936 C  CD1 . TRP A 1 299 ? 146.096 175.443 175.243 1.00 77.28  ? 299 TRP A CD1 1 
ATOM   1937 C  CD2 . TRP A 1 299 ? 146.662 174.925 173.144 1.00 77.28  ? 299 TRP A CD2 1 
ATOM   1938 N  NE1 . TRP A 1 299 ? 144.944 175.139 174.563 1.00 77.28  ? 299 TRP A NE1 1 
ATOM   1939 C  CE2 . TRP A 1 299 ? 145.265 174.819 173.271 1.00 77.28  ? 299 TRP A CE2 1 
ATOM   1940 C  CE3 . TRP A 1 299 ? 147.250 174.650 171.907 1.00 77.28  ? 299 TRP A CE3 1 
ATOM   1941 C  CZ2 . TRP A 1 299 ? 144.447 174.449 172.209 1.00 77.28  ? 299 TRP A CZ2 1 
ATOM   1942 C  CZ3 . TRP A 1 299 ? 146.437 174.281 170.854 1.00 77.28  ? 299 TRP A CZ3 1 
ATOM   1943 C  CH2 . TRP A 1 299 ? 145.051 174.184 171.011 1.00 77.28  ? 299 TRP A CH2 1 
ATOM   1944 N  N   . VAL A 1 300 ? 151.098 175.363 176.664 1.00 72.27  ? 300 VAL A N   1 
ATOM   1945 C  CA  . VAL A 1 300 ? 152.495 175.679 176.953 1.00 72.27  ? 300 VAL A CA  1 
ATOM   1946 C  C   . VAL A 1 300 ? 153.273 174.409 177.276 1.00 72.27  ? 300 VAL A C   1 
ATOM   1947 O  O   . VAL A 1 300 ? 154.368 174.176 176.744 1.00 72.27  ? 300 VAL A O   1 
ATOM   1948 C  CB  . VAL A 1 300 ? 152.583 176.702 178.100 1.00 72.27  ? 300 VAL A CB  1 
ATOM   1949 C  CG1 . VAL A 1 300 ? 153.985 176.749 178.674 1.00 72.27  ? 300 VAL A CG1 1 
ATOM   1950 C  CG2 . VAL A 1 300 ? 152.168 178.072 177.616 1.00 72.27  ? 300 VAL A CG2 1 
ATOM   1951 N  N   . ASP A 1 301 ? 152.703 173.554 178.130 1.00 73.67  ? 301 ASP A N   1 
ATOM   1952 C  CA  . ASP A 1 301 ? 153.393 172.335 178.528 1.00 73.67  ? 301 ASP A CA  1 
ATOM   1953 C  C   . ASP A 1 301 ? 153.511 171.347 177.378 1.00 73.67  ? 301 ASP A C   1 
ATOM   1954 O  O   . ASP A 1 301 ? 154.539 170.679 177.260 1.00 73.67  ? 301 ASP A O   1 
ATOM   1955 C  CB  . ASP A 1 301 ? 152.685 171.705 179.723 1.00 73.67  ? 301 ASP A CB  1 
ATOM   1956 C  CG  . ASP A 1 301 ? 152.816 172.546 180.975 1.00 73.67  ? 301 ASP A CG  1 
ATOM   1957 O  OD1 . ASP A 1 301 ? 153.581 173.533 180.946 1.00 73.67  ? 301 ASP A OD1 1 
ATOM   1958 O  OD2 . ASP A 1 301 ? 152.158 172.232 181.987 1.00 73.67  ? 301 ASP A OD2 1 
ATOM   1959 N  N   . ALA A 1 302 ? 152.509 171.272 176.498 1.00 72.99  ? 302 ALA A N   1 
ATOM   1960 C  CA  . ALA A 1 302 ? 152.612 170.394 175.337 1.00 72.99  ? 302 ALA A CA  1 
ATOM   1961 C  C   . ALA A 1 302 ? 153.695 170.864 174.377 1.00 72.99  ? 302 ALA A C   1 
ATOM   1962 O  O   . ALA A 1 302 ? 154.526 170.064 173.925 1.00 72.99  ? 302 ALA A O   1 
ATOM   1963 C  CB  . ALA A 1 302 ? 151.265 170.312 174.623 1.00 72.99  ? 302 ALA A CB  1 
ATOM   1964 N  N   . GLY A 1 303 ? 153.708 172.164 174.064 1.00 75.48  ? 303 GLY A N   1 
ATOM   1965 C  CA  . GLY A 1 303 ? 154.709 172.680 173.144 1.00 75.48  ? 303 GLY A CA  1 
ATOM   1966 C  C   . GLY A 1 303 ? 156.122 172.551 173.677 1.00 75.48  ? 303 GLY A C   1 
ATOM   1967 O  O   . GLY A 1 303 ? 157.037 172.133 172.959 1.00 75.48  ? 303 GLY A O   1 
ATOM   1968 N  N   . THR A 1 304 ? 156.317 172.863 174.950 1.00 72.84  ? 304 THR A N   1 
ATOM   1969 C  CA  . THR A 1 304 ? 157.662 172.757 175.481 1.00 72.84  ? 304 THR A CA  1 
ATOM   1970 C  C   . THR A 1 304 ? 158.042 171.333 175.860 1.00 72.84  ? 304 THR A C   1 
ATOM   1971 O  O   . THR A 1 304 ? 159.233 171.048 175.965 1.00 72.84  ? 304 THR A O   1 
ATOM   1972 C  CB  . THR A 1 304 ? 157.810 173.706 176.655 1.00 72.84  ? 304 THR A CB  1 
ATOM   1973 O  OG1 . THR A 1 304 ? 156.878 173.348 177.681 1.00 72.84  ? 304 THR A OG1 1 
ATOM   1974 C  CG2 . THR A 1 304 ? 157.502 175.103 176.165 1.00 72.84  ? 304 THR A CG2 1 
ATOM   1975 N  N   . GLN A 1 305 ? 157.081 170.415 175.985 1.00 72.47  ? 305 GLN A N   1 
ATOM   1976 C  CA  . GLN A 1 305 ? 157.429 169.002 176.075 1.00 72.47  ? 305 GLN A CA  1 
ATOM   1977 C  C   . GLN A 1 305 ? 157.894 168.473 174.726 1.00 72.47  ? 305 GLN A C   1 
ATOM   1978 O  O   . GLN A 1 305 ? 158.832 167.668 174.660 1.00 72.47  ? 305 GLN A O   1 
ATOM   1979 C  CB  . GLN A 1 305 ? 156.233 168.207 176.596 1.00 72.47  ? 305 GLN A CB  1 
ATOM   1980 C  CG  . GLN A 1 305 ? 156.370 166.705 176.480 1.00 72.47  ? 305 GLN A CG  1 
ATOM   1981 C  CD  . GLN A 1 305 ? 157.606 166.179 177.170 1.00 72.47  ? 305 GLN A CD  1 
ATOM   1982 O  OE1 . GLN A 1 305 ? 157.940 166.600 178.275 1.00 72.47  ? 305 GLN A OE1 1 
ATOM   1983 N  NE2 . GLN A 1 305 ? 158.300 165.258 176.515 1.00 72.47  ? 305 GLN A NE2 1 
ATOM   1984 N  N   . ILE A 1 306 ? 157.251 168.922 173.642 1.00 75.55  ? 306 ILE A N   1 
ATOM   1985 C  CA  . ILE A 1 306 ? 157.753 168.648 172.294 1.00 75.55  ? 306 ILE A CA  1 
ATOM   1986 C  C   . ILE A 1 306 ? 159.176 169.167 172.136 1.00 75.55  ? 306 ILE A C   1 
ATOM   1987 O  O   . ILE A 1 306 ? 160.062 168.459 171.644 1.00 75.55  ? 306 ILE A O   1 
ATOM   1988 C  CB  . ILE A 1 306 ? 156.813 169.255 171.237 1.00 75.55  ? 306 ILE A CB  1 
ATOM   1989 C  CG1 . ILE A 1 306 ? 155.478 168.520 171.217 1.00 75.55  ? 306 ILE A CG1 1 
ATOM   1990 C  CG2 . ILE A 1 306 ? 157.451 169.240 169.866 1.00 75.55  ? 306 ILE A CG2 1 
ATOM   1991 C  CD1 . ILE A 1 306 ? 155.616 167.084 170.795 1.00 75.55  ? 306 ILE A CD1 1 
ATOM   1992 N  N   . PHE A 1 307 ? 159.424 170.401 172.578 1.00 78.70  ? 307 PHE A N   1 
ATOM   1993 C  CA  . PHE A 1 307 ? 160.761 170.971 172.423 1.00 78.70  ? 307 PHE A CA  1 
ATOM   1994 C  C   . PHE A 1 307 ? 161.787 170.299 173.332 1.00 78.70  ? 307 PHE A C   1 
ATOM   1995 O  O   . PHE A 1 307 ? 162.948 170.146 172.941 1.00 78.70  ? 307 PHE A O   1 
ATOM   1996 C  CB  . PHE A 1 307 ? 160.725 172.475 172.682 1.00 78.70  ? 307 PHE A CB  1 
ATOM   1997 C  CG  . PHE A 1 307 ? 160.017 173.256 171.614 1.00 78.70  ? 307 PHE A CG  1 
ATOM   1998 C  CD1 . PHE A 1 307 ? 159.798 172.706 170.363 1.00 78.70  ? 307 PHE A CD1 1 
ATOM   1999 C  CD2 . PHE A 1 307 ? 159.556 174.533 171.866 1.00 78.70  ? 307 PHE A CD2 1 
ATOM   2000 C  CE1 . PHE A 1 307 ? 159.146 173.419 169.385 1.00 78.70  ? 307 PHE A CE1 1 
ATOM   2001 C  CE2 . PHE A 1 307 ? 158.898 175.249 170.892 1.00 78.70  ? 307 PHE A CE2 1 
ATOM   2002 C  CZ  . PHE A 1 307 ? 158.695 174.693 169.649 1.00 78.70  ? 307 PHE A CZ  1 
ATOM   2003 N  N   . PHE A 1 308 ? 161.387 169.890 174.536 1.00 76.63  ? 308 PHE A N   1 
ATOM   2004 C  CA  . PHE A 1 308 ? 162.307 169.261 175.474 1.00 76.63  ? 308 PHE A CA  1 
ATOM   2005 C  C   . PHE A 1 308 ? 162.670 167.842 175.060 1.00 76.63  ? 308 PHE A C   1 
ATOM   2006 O  O   . PHE A 1 308 ? 163.844 167.462 175.111 1.00 76.63  ? 308 PHE A O   1 
ATOM   2007 C  CB  . PHE A 1 308 ? 161.691 169.262 176.872 1.00 76.63  ? 308 PHE A CB  1 
ATOM   2008 C  CG  . PHE A 1 308 ? 162.604 168.747 177.943 1.00 76.63  ? 308 PHE A CG  1 
ATOM   2009 C  CD1 . PHE A 1 308 ? 163.531 169.579 178.535 1.00 76.63  ? 308 PHE A CD1 1 
ATOM   2010 C  CD2 . PHE A 1 308 ? 162.517 167.433 178.375 1.00 76.63  ? 308 PHE A CD2 1 
ATOM   2011 C  CE1 . PHE A 1 308 ? 164.366 169.109 179.523 1.00 76.63  ? 308 PHE A CE1 1 
ATOM   2012 C  CE2 . PHE A 1 308 ? 163.350 166.957 179.363 1.00 76.63  ? 308 PHE A CE2 1 
ATOM   2013 C  CZ  . PHE A 1 308 ? 164.275 167.797 179.939 1.00 76.63  ? 308 PHE A CZ  1 
ATOM   2014 N  N   . SER A 1 309 ? 161.679 167.042 174.661 1.00 81.25  ? 309 SER A N   1 
ATOM   2015 C  CA  . SER A 1 309 ? 161.925 165.629 174.399 1.00 81.25  ? 309 SER A CA  1 
ATOM   2016 C  C   . SER A 1 309 ? 162.751 165.400 173.144 1.00 81.25  ? 309 SER A C   1 
ATOM   2017 O  O   . SER A 1 309 ? 163.402 164.357 173.029 1.00 81.25  ? 309 SER A O   1 
ATOM   2018 C  CB  . SER A 1 309 ? 160.601 164.876 174.287 1.00 81.25  ? 309 SER A CB  1 
ATOM   2019 O  OG  . SER A 1 309 ? 160.824 163.514 173.970 1.00 81.25  ? 309 SER A OG  1 
ATOM   2020 N  N   . TYR A 1 310 ? 162.745 166.345 172.209 1.00 88.91  ? 310 TYR A N   1 
ATOM   2021 C  CA  . TYR A 1 310 ? 163.506 166.232 170.974 1.00 88.91  ? 310 TYR A CA  1 
ATOM   2022 C  C   . TYR A 1 310 ? 164.869 166.894 171.078 1.00 88.91  ? 310 TYR A C   1 
ATOM   2023 O  O   . TYR A 1 310 ? 165.571 166.988 170.066 1.00 88.91  ? 310 TYR A O   1 
ATOM   2024 C  CB  . TYR A 1 310 ? 162.730 166.860 169.812 1.00 88.91  ? 310 TYR A CB  1 
ATOM   2025 C  CG  . TYR A 1 310 ? 161.395 166.219 169.518 1.00 88.91  ? 310 TYR A CG  1 
ATOM   2026 C  CD1 . TYR A 1 310 ? 161.127 164.909 169.892 1.00 88.91  ? 310 TYR A CD1 1 
ATOM   2027 C  CD2 . TYR A 1 310 ? 160.388 166.939 168.895 1.00 88.91  ? 310 TYR A CD2 1 
ATOM   2028 C  CE1 . TYR A 1 310 ? 159.902 164.332 169.636 1.00 88.91  ? 310 TYR A CE1 1 
ATOM   2029 C  CE2 . TYR A 1 310 ? 159.160 166.373 168.644 1.00 88.91  ? 310 TYR A CE2 1 
ATOM   2030 C  CZ  . TYR A 1 310 ? 158.922 165.067 169.011 1.00 88.91  ? 310 TYR A CZ  1 
ATOM   2031 O  OH  . TYR A 1 310 ? 157.699 164.495 168.754 1.00 88.91  ? 310 TYR A OH  1 
ATOM   2032 N  N   . ALA A 1 311 ? 165.233 167.377 172.271 1.00 94.77  ? 311 ALA A N   1 
ATOM   2033 C  CA  . ALA A 1 311 ? 166.391 168.235 172.529 1.00 94.77  ? 311 ALA A CA  1 
ATOM   2034 C  C   . ALA A 1 311 ? 166.358 169.520 171.705 1.00 94.77  ? 311 ALA A C   1 
ATOM   2035 O  O   . ALA A 1 311 ? 167.400 170.136 171.467 1.00 94.77  ? 311 ALA A O   1 
ATOM   2036 C  CB  . ALA A 1 311 ? 167.717 167.493 172.312 1.00 94.77  ? 311 ALA A CB  1 
ATOM   2037 N  N   . ILE A 1 312 ? 165.165 169.943 171.284 1.00 91.52  ? 312 ILE A N   1 
ATOM   2038 C  CA  . ILE A 1 312 ? 165.015 171.151 170.483 1.00 91.52  ? 312 ILE A CA  1 
ATOM   2039 C  C   . ILE A 1 312 ? 165.221 172.367 171.374 1.00 91.52  ? 312 ILE A C   1 
ATOM   2040 O  O   . ILE A 1 312 ? 164.686 172.432 172.489 1.00 91.52  ? 312 ILE A O   1 
ATOM   2041 C  CB  . ILE A 1 312 ? 163.636 171.168 169.806 1.00 91.52  ? 312 ILE A CB  1 
ATOM   2042 C  CG1 . ILE A 1 312 ? 163.626 170.248 168.585 1.00 91.52  ? 312 ILE A CG1 1 
ATOM   2043 C  CG2 . ILE A 1 312 ? 163.235 172.572 169.402 1.00 91.52  ? 312 ILE A CG2 1 
ATOM   2044 C  CD1 . ILE A 1 312 ? 162.250 170.049 167.993 1.00 91.52  ? 312 ILE A CD1 1 
ATOM   2045 N  N   . CYS A 1 313 ? 166.041 173.311 170.902 1.00 96.19  ? 313 CYS A N   1 
ATOM   2046 C  CA  . CYS A 1 313 ? 166.396 174.566 171.565 1.00 96.19  ? 313 CYS A CA  1 
ATOM   2047 C  C   . CYS A 1 313 ? 167.175 174.359 172.859 1.00 96.19  ? 313 CYS A C   1 
ATOM   2048 O  O   . CYS A 1 313 ? 167.402 175.323 173.598 1.00 96.19  ? 313 CYS A O   1 
ATOM   2049 C  CB  . CYS A 1 313 ? 165.165 175.446 171.832 1.00 96.19  ? 313 CYS A CB  1 
ATOM   2050 S  SG  . CYS A 1 313 ? 164.332 176.035 170.345 1.00 96.19  ? 313 CYS A SG  1 
ATOM   2051 N  N   . LEU A 1 314 ? 167.590 173.126 173.157 1.00 96.16  ? 314 LEU A N   1 
ATOM   2052 C  CA  . LEU A 1 314 ? 168.470 172.906 174.296 1.00 96.16  ? 314 LEU A CA  1 
ATOM   2053 C  C   . LEU A 1 314 ? 169.884 173.369 173.982 1.00 96.16  ? 314 LEU A C   1 
ATOM   2054 O  O   . LEU A 1 314 ? 170.529 174.016 174.813 1.00 96.16  ? 314 LEU A O   1 
ATOM   2055 C  CB  . LEU A 1 314 ? 168.458 171.431 174.696 1.00 96.16  ? 314 LEU A CB  1 
ATOM   2056 C  CG  . LEU A 1 314 ? 167.139 170.839 175.202 1.00 96.16  ? 314 LEU A CG  1 
ATOM   2057 C  CD1 . LEU A 1 314 ? 167.396 169.550 175.966 1.00 96.16  ? 314 LEU A CD1 1 
ATOM   2058 C  CD2 . LEU A 1 314 ? 166.376 171.828 176.069 1.00 96.16  ? 314 LEU A CD2 1 
ATOM   2059 N  N   . GLY A 1 315 ? 170.375 173.065 172.784 1.00 101.69 ? 315 GLY A N   1 
ATOM   2060 C  CA  . GLY A 1 315 ? 171.694 173.502 172.374 1.00 101.69 ? 315 GLY A CA  1 
ATOM   2061 C  C   . GLY A 1 315 ? 172.590 172.382 171.890 1.00 101.69 ? 315 GLY A C   1 
ATOM   2062 O  O   . GLY A 1 315 ? 173.624 172.634 171.264 1.00 101.69 ? 315 GLY A O   1 
ATOM   2063 N  N   . CYS A 1 316 ? 172.210 171.137 172.177 1.00 107.45 ? 316 CYS A N   1 
ATOM   2064 C  CA  . CYS A 1 316 ? 173.010 169.993 171.763 1.00 107.45 ? 316 CYS A CA  1 
ATOM   2065 C  C   . CYS A 1 316 ? 172.673 169.502 170.362 1.00 107.45 ? 316 CYS A C   1 
ATOM   2066 O  O   . CYS A 1 316 ? 173.426 168.690 169.815 1.00 107.45 ? 316 CYS A O   1 
ATOM   2067 C  CB  . CYS A 1 316 ? 172.842 168.846 172.763 1.00 107.45 ? 316 CYS A CB  1 
ATOM   2068 S  SG  . CYS A 1 316 ? 171.131 168.479 173.200 1.00 107.45 ? 316 CYS A SG  1 
ATOM   2069 N  N   . LEU A 1 317 ? 171.579 169.976 169.764 1.00 103.42 ? 317 LEU A N   1 
ATOM   2070 C  CA  . LEU A 1 317 ? 171.215 169.530 168.422 1.00 103.42 ? 317 LEU A CA  1 
ATOM   2071 C  C   . LEU A 1 317 ? 172.103 170.142 167.348 1.00 103.42 ? 317 LEU A C   1 
ATOM   2072 O  O   . LEU A 1 317 ? 172.385 169.485 166.340 1.00 103.42 ? 317 LEU A O   1 
ATOM   2073 C  CB  . LEU A 1 317 ? 169.749 169.853 168.141 1.00 103.42 ? 317 LEU A CB  1 
ATOM   2074 C  CG  . LEU A 1 317 ? 168.741 168.873 168.738 1.00 103.42 ? 317 LEU A CG  1 
ATOM   2075 C  CD1 . LEU A 1 317 ? 167.349 169.180 168.237 1.00 103.42 ? 317 LEU A CD1 1 
ATOM   2076 C  CD2 . LEU A 1 317 ? 169.119 167.440 168.402 1.00 103.42 ? 317 LEU A CD2 1 
ATOM   2077 N  N   . THR A 1 318 ? 172.534 171.392 167.533 1.00 106.00 ? 318 THR A N   1 
ATOM   2078 C  CA  . THR A 1 318 ? 173.492 171.991 166.610 1.00 106.00 ? 318 THR A CA  1 
ATOM   2079 C  C   . THR A 1 318 ? 174.834 171.271 166.678 1.00 106.00 ? 318 THR A C   1 
ATOM   2080 O  O   . THR A 1 318 ? 175.500 171.079 165.654 1.00 106.00 ? 318 THR A O   1 
ATOM   2081 C  CB  . THR A 1 318 ? 173.652 173.480 166.919 1.00 106.00 ? 318 THR A CB  1 
ATOM   2082 O  OG1 . THR A 1 318 ? 172.359 174.095 166.976 1.00 106.00 ? 318 THR A OG1 1 
ATOM   2083 C  CG2 . THR A 1 318 ? 174.475 174.173 165.847 1.00 106.00 ? 318 THR A CG2 1 
ATOM   2084 N  N   . ALA A 1 319 ? 175.241 170.854 167.879 1.00 111.11 ? 319 ALA A N   1 
ATOM   2085 C  CA  . ALA A 1 319 ? 176.457 170.060 168.016 1.00 111.11 ? 319 ALA A CA  1 
ATOM   2086 C  C   . ALA A 1 319 ? 176.288 168.662 167.435 1.00 111.11 ? 319 ALA A C   1 
ATOM   2087 O  O   . ALA A 1 319 ? 177.254 168.087 166.921 1.00 111.11 ? 319 ALA A O   1 
ATOM   2088 C  CB  . ALA A 1 319 ? 176.868 169.979 169.485 1.00 111.11 ? 319 ALA A CB  1 
ATOM   2089 N  N   . LEU A 1 320 ? 175.080 168.096 167.521 1.00 110.70 ? 320 LEU A N   1 
ATOM   2090 C  CA  . LEU A 1 320 ? 174.829 166.775 166.952 1.00 110.70 ? 320 LEU A CA  1 
ATOM   2091 C  C   . LEU A 1 320 ? 174.916 166.801 165.431 1.00 110.70 ? 320 LEU A C   1 
ATOM   2092 O  O   . LEU A 1 320 ? 175.437 165.862 164.817 1.00 110.70 ? 320 LEU A O   1 
ATOM   2093 C  CB  . LEU A 1 320 ? 173.461 166.262 167.408 1.00 110.70 ? 320 LEU A CB  1 
ATOM   2094 C  CG  . LEU A 1 320 ? 172.890 165.022 166.716 1.00 110.70 ? 320 LEU A CG  1 
ATOM   2095 C  CD1 . LEU A 1 320 ? 173.764 163.806 166.987 1.00 110.70 ? 320 LEU A CD1 1 
ATOM   2096 C  CD2 . LEU A 1 320 ? 171.460 164.763 167.159 1.00 110.70 ? 320 LEU A CD2 1 
ATOM   2097 N  N   . GLY A 1 321 ? 174.409 167.867 164.808 1.00 112.13 ? 321 GLY A N   1 
ATOM   2098 C  CA  . GLY A 1 321 ? 174.521 167.995 163.364 1.00 112.13 ? 321 GLY A CA  1 
ATOM   2099 C  C   . GLY A 1 321 ? 175.954 168.177 162.899 1.00 112.13 ? 321 GLY A C   1 
ATOM   2100 O  O   . GLY A 1 321 ? 176.332 167.703 161.824 1.00 112.13 ? 321 GLY A O   1 
ATOM   2101 N  N   . SER A 1 322 ? 176.770 168.866 163.702 1.00 111.50 ? 322 SER A N   1 
ATOM   2102 C  CA  . SER A 1 322 ? 178.171 169.080 163.356 1.00 111.50 ? 322 SER A CA  1 
ATOM   2103 C  C   . SER A 1 322 ? 178.981 167.790 163.366 1.00 111.50 ? 322 SER A C   1 
ATOM   2104 O  O   . SER A 1 322 ? 180.029 167.729 162.715 1.00 111.50 ? 322 SER A O   1 
ATOM   2105 C  CB  . SER A 1 322 ? 178.798 170.089 164.317 1.00 111.50 ? 322 SER A CB  1 
ATOM   2106 O  OG  . SER A 1 322 ? 178.820 169.585 165.641 1.00 111.50 ? 322 SER A OG  1 
ATOM   2107 N  N   . TYR A 1 323 ? 178.527 166.768 164.097 1.00 116.20 ? 323 TYR A N   1 
ATOM   2108 C  CA  . TYR A 1 323 ? 179.215 165.481 164.083 1.00 116.20 ? 323 TYR A CA  1 
ATOM   2109 C  C   . TYR A 1 323 ? 179.093 164.795 162.729 1.00 116.20 ? 323 TYR A C   1 
ATOM   2110 O  O   . TYR A 1 323 ? 180.046 164.153 162.273 1.00 116.20 ? 323 TYR A O   1 
ATOM   2111 C  CB  . TYR A 1 323 ? 178.660 164.574 165.183 1.00 116.20 ? 323 TYR A CB  1 
ATOM   2112 C  CG  . TYR A 1 323 ? 179.167 164.886 166.575 1.00 116.20 ? 323 TYR A CG  1 
ATOM   2113 C  CD1 . TYR A 1 323 ? 180.132 165.864 166.787 1.00 116.20 ? 323 TYR A CD1 1 
ATOM   2114 C  CD2 . TYR A 1 323 ? 178.676 164.200 167.680 1.00 116.20 ? 323 TYR A CD2 1 
ATOM   2115 C  CE1 . TYR A 1 323 ? 180.593 166.149 168.059 1.00 116.20 ? 323 TYR A CE1 1 
ATOM   2116 C  CE2 . TYR A 1 323 ? 179.132 164.477 168.955 1.00 116.20 ? 323 TYR A CE2 1 
ATOM   2117 C  CZ  . TYR A 1 323 ? 180.090 165.452 169.138 1.00 116.20 ? 323 TYR A CZ  1 
ATOM   2118 O  OH  . TYR A 1 323 ? 180.546 165.731 170.406 1.00 116.20 ? 323 TYR A OH  1 
ATOM   2119 N  N   . ASN A 1 324 ? 177.939 164.916 162.080 1.00 117.06 ? 324 ASN A N   1 
ATOM   2120 C  CA  . ASN A 1 324 ? 177.715 164.288 160.788 1.00 117.06 ? 324 ASN A CA  1 
ATOM   2121 C  C   . ASN A 1 324 ? 178.494 165.013 159.695 1.00 117.06 ? 324 ASN A C   1 
ATOM   2122 O  O   . ASN A 1 324 ? 178.905 166.167 159.846 1.00 117.06 ? 324 ASN A O   1 
ATOM   2123 C  CB  . ASN A 1 324 ? 176.225 164.277 160.445 1.00 117.06 ? 324 ASN A CB  1 
ATOM   2124 C  CG  . ASN A 1 324 ? 175.393 163.538 161.474 1.00 117.06 ? 324 ASN A CG  1 
ATOM   2125 O  OD1 . ASN A 1 324 ? 175.882 162.635 162.154 1.00 117.06 ? 324 ASN A OD1 1 
ATOM   2126 N  ND2 . ASN A 1 324 ? 174.127 163.919 161.594 1.00 117.06 ? 324 ASN A ND2 1 
ATOM   2127 N  N   . ASN A 1 325 ? 178.692 164.316 158.580 1.00 114.88 ? 325 ASN A N   1 
ATOM   2128 C  CA  . ASN A 1 325 ? 179.374 164.892 157.434 1.00 114.88 ? 325 ASN A CA  1 
ATOM   2129 C  C   . ASN A 1 325 ? 178.446 165.858 156.700 1.00 114.88 ? 325 ASN A C   1 
ATOM   2130 O  O   . ASN A 1 325 ? 177.263 165.997 157.023 1.00 114.88 ? 325 ASN A O   1 
ATOM   2131 C  CB  . ASN A 1 325 ? 179.878 163.791 156.504 1.00 114.88 ? 325 ASN A CB  1 
ATOM   2132 C  CG  . ASN A 1 325 ? 178.822 162.745 156.212 1.00 114.88 ? 325 ASN A CG  1 
ATOM   2133 O  OD1 . ASN A 1 325 ? 177.707 162.811 156.728 1.00 114.88 ? 325 ASN A OD1 1 
ATOM   2134 N  ND2 . ASN A 1 325 ? 179.168 161.771 155.379 1.00 114.88 ? 325 ASN A ND2 1 
ATOM   2135 N  N   . TYR A 1 326 ? 178.992 166.535 155.688 1.00 110.69 ? 326 TYR A N   1 
ATOM   2136 C  CA  . TYR A 1 326 ? 178.242 167.568 154.982 1.00 110.69 ? 326 TYR A CA  1 
ATOM   2137 C  C   . TYR A 1 326 ? 177.138 167.001 154.098 1.00 110.69 ? 326 TYR A C   1 
ATOM   2138 O  O   . TYR A 1 326 ? 176.210 167.736 153.744 1.00 110.69 ? 326 TYR A O   1 
ATOM   2139 C  CB  . TYR A 1 326 ? 179.193 168.417 154.138 1.00 110.69 ? 326 TYR A CB  1 
ATOM   2140 C  CG  . TYR A 1 326 ? 178.586 169.709 153.642 1.00 110.69 ? 326 TYR A CG  1 
ATOM   2141 C  CD1 . TYR A 1 326 ? 178.330 170.757 154.515 1.00 110.69 ? 326 TYR A CD1 1 
ATOM   2142 C  CD2 . TYR A 1 326 ? 178.266 169.878 152.302 1.00 110.69 ? 326 TYR A CD2 1 
ATOM   2143 C  CE1 . TYR A 1 326 ? 177.775 171.941 154.065 1.00 110.69 ? 326 TYR A CE1 1 
ATOM   2144 C  CE2 . TYR A 1 326 ? 177.710 171.058 151.843 1.00 110.69 ? 326 TYR A CE2 1 
ATOM   2145 C  CZ  . TYR A 1 326 ? 177.467 172.085 152.730 1.00 110.69 ? 326 TYR A CZ  1 
ATOM   2146 O  OH  . TYR A 1 326 ? 176.915 173.261 152.281 1.00 110.69 ? 326 TYR A OH  1 
ATOM   2147 N  N   . HIS A 1 327 ? 177.201 165.716 153.743 1.00 111.62 ? 327 HIS A N   1 
ATOM   2148 C  CA  . HIS A 1 327 ? 176.241 165.127 152.817 1.00 111.62 ? 327 HIS A CA  1 
ATOM   2149 C  C   . HIS A 1 327 ? 175.309 164.128 153.496 1.00 111.62 ? 327 HIS A C   1 
ATOM   2150 O  O   . HIS A 1 327 ? 174.723 163.276 152.820 1.00 111.62 ? 327 HIS A O   1 
ATOM   2151 C  CB  . HIS A 1 327 ? 176.971 164.469 151.645 1.00 111.62 ? 327 HIS A CB  1 
ATOM   2152 C  CG  . HIS A 1 327 ? 177.382 165.434 150.576 1.00 111.62 ? 327 HIS A CG  1 
ATOM   2153 N  ND1 . HIS A 1 327 ? 178.683 165.859 150.418 1.00 111.62 ? 327 HIS A ND1 1 
ATOM   2154 C  CD2 . HIS A 1 327 ? 176.662 166.060 149.616 1.00 111.62 ? 327 HIS A CD2 1 
ATOM   2155 C  CE1 . HIS A 1 327 ? 178.748 166.704 149.404 1.00 111.62 ? 327 HIS A CE1 1 
ATOM   2156 N  NE2 . HIS A 1 327 ? 177.535 166.843 148.901 1.00 111.62 ? 327 HIS A NE2 1 
ATOM   2157 N  N   . ASN A 1 328 ? 175.162 164.209 154.815 1.00 108.64 ? 328 ASN A N   1 
ATOM   2158 C  CA  . ASN A 1 328 ? 174.196 163.372 155.511 1.00 108.64 ? 328 ASN A CA  1 
ATOM   2159 C  C   . ASN A 1 328 ? 172.776 163.861 155.243 1.00 108.64 ? 328 ASN A C   1 
ATOM   2160 O  O   . ASN A 1 328 ? 172.531 165.054 155.047 1.00 108.64 ? 328 ASN A O   1 
ATOM   2161 C  CB  . ASN A 1 328 ? 174.474 163.369 157.014 1.00 108.64 ? 328 ASN A CB  1 
ATOM   2162 C  CG  . ASN A 1 328 ? 174.041 162.080 157.681 1.00 108.64 ? 328 ASN A CG  1 
ATOM   2163 O  OD1 . ASN A 1 328 ? 173.899 161.046 157.028 1.00 108.64 ? 328 ASN A OD1 1 
ATOM   2164 N  ND2 . ASN A 1 328 ? 173.831 162.133 158.991 1.00 108.64 ? 328 ASN A ND2 1 
ATOM   2165 N  N   . ASN A 1 329 ? 171.834 162.922 155.239 1.00 106.07 ? 329 ASN A N   1 
ATOM   2166 C  CA  . ASN A 1 329 ? 170.439 163.232 154.942 1.00 106.07 ? 329 ASN A CA  1 
ATOM   2167 C  C   . ASN A 1 329 ? 169.768 163.773 156.200 1.00 106.07 ? 329 ASN A C   1 
ATOM   2168 O  O   . ASN A 1 329 ? 169.553 163.034 157.166 1.00 106.07 ? 329 ASN A O   1 
ATOM   2169 C  CB  . ASN A 1 329 ? 169.719 161.990 154.424 1.00 106.07 ? 329 ASN A CB  1 
ATOM   2170 C  CG  . ASN A 1 329 ? 168.525 162.329 153.555 1.00 106.07 ? 329 ASN A CG  1 
ATOM   2171 O  OD1 . ASN A 1 329 ? 168.260 163.496 153.272 1.00 106.07 ? 329 ASN A OD1 1 
ATOM   2172 N  ND2 . ASN A 1 329 ? 167.797 161.305 153.124 1.00 106.07 ? 329 ASN A ND2 1 
ATOM   2173 N  N   . CYS A 1 330 ? 169.440 165.068 156.192 1.00 102.28 ? 330 CYS A N   1 
ATOM   2174 C  CA  . CYS A 1 330 ? 168.786 165.675 157.347 1.00 102.28 ? 330 CYS A CA  1 
ATOM   2175 C  C   . CYS A 1 330 ? 167.320 165.272 157.439 1.00 102.28 ? 330 CYS A C   1 
ATOM   2176 O  O   . CYS A 1 330 ? 166.814 165.005 158.535 1.00 102.28 ? 330 CYS A O   1 
ATOM   2177 C  CB  . CYS A 1 330 ? 168.894 167.197 157.277 1.00 102.28 ? 330 CYS A CB  1 
ATOM   2178 S  SG  . CYS A 1 330 ? 170.547 167.864 157.466 1.00 102.28 ? 330 CYS A SG  1 
ATOM   2179 N  N   . TYR A 1 331 ? 166.627 165.232 156.299 1.00 98.81  ? 331 TYR A N   1 
ATOM   2180 C  CA  . TYR A 1 331 ? 165.168 165.158 156.296 1.00 98.81  ? 331 TYR A CA  1 
ATOM   2181 C  C   . TYR A 1 331 ? 164.669 163.807 156.795 1.00 98.81  ? 331 TYR A C   1 
ATOM   2182 O  O   . TYR A 1 331 ? 163.797 163.742 157.672 1.00 98.81  ? 331 TYR A O   1 
ATOM   2183 C  CB  . TYR A 1 331 ? 164.652 165.441 154.886 1.00 98.81  ? 331 TYR A CB  1 
ATOM   2184 C  CG  . TYR A 1 331 ? 163.156 165.602 154.772 1.00 98.81  ? 331 TYR A CG  1 
ATOM   2185 C  CD1 . TYR A 1 331 ? 162.534 166.777 155.167 1.00 98.81  ? 331 TYR A CD1 1 
ATOM   2186 C  CD2 . TYR A 1 331 ? 162.368 164.585 154.249 1.00 98.81  ? 331 TYR A CD2 1 
ATOM   2187 C  CE1 . TYR A 1 331 ? 161.166 166.932 155.055 1.00 98.81  ? 331 TYR A CE1 1 
ATOM   2188 C  CE2 . TYR A 1 331 ? 160.999 164.731 154.134 1.00 98.81  ? 331 TYR A CE2 1 
ATOM   2189 C  CZ  . TYR A 1 331 ? 160.404 165.906 154.538 1.00 98.81  ? 331 TYR A CZ  1 
ATOM   2190 O  OH  . TYR A 1 331 ? 159.041 166.058 154.427 1.00 98.81  ? 331 TYR A OH  1 
ATOM   2191 N  N   . ARG A 1 332 ? 165.222 162.716 156.255 1.00 102.13 ? 332 ARG A N   1 
ATOM   2192 C  CA  . ARG A 1 332 ? 164.773 161.381 156.639 1.00 102.13 ? 332 ARG A CA  1 
ATOM   2193 C  C   . ARG A 1 332 ? 165.118 161.078 158.092 1.00 102.13 ? 332 ARG A C   1 
ATOM   2194 O  O   . ARG A 1 332 ? 164.284 160.539 158.834 1.00 102.13 ? 332 ARG A O   1 
ATOM   2195 C  CB  . ARG A 1 332 ? 165.383 160.338 155.699 1.00 102.13 ? 332 ARG A CB  1 
ATOM   2196 C  CG  . ARG A 1 332 ? 165.687 158.988 156.334 1.00 102.13 ? 332 ARG A CG  1 
ATOM   2197 C  CD  . ARG A 1 332 ? 165.611 157.866 155.311 1.00 102.13 ? 332 ARG A CD  1 
ATOM   2198 N  NE  . ARG A 1 332 ? 164.243 157.611 154.877 1.00 102.13 ? 332 ARG A NE  1 
ATOM   2199 C  CZ  . ARG A 1 332 ? 163.913 156.803 153.878 1.00 102.13 ? 332 ARG A CZ  1 
ATOM   2200 N  NH1 . ARG A 1 332 ? 164.832 156.151 153.184 1.00 102.13 ? 332 ARG A NH1 1 
ATOM   2201 N  NH2 . ARG A 1 332 ? 162.629 156.645 153.568 1.00 102.13 ? 332 ARG A NH2 1 
ATOM   2202 N  N   . ASP A 1 333 ? 166.334 161.444 158.516 1.00 104.87 ? 333 ASP A N   1 
ATOM   2203 C  CA  . ASP A 1 333 ? 166.749 161.233 159.900 1.00 104.87 ? 333 ASP A CA  1 
ATOM   2204 C  C   . ASP A 1 333 ? 165.880 162.028 160.863 1.00 104.87 ? 333 ASP A C   1 
ATOM   2205 O  O   . ASP A 1 333 ? 165.451 161.504 161.898 1.00 104.87 ? 333 ASP A O   1 
ATOM   2206 C  CB  . ASP A 1 333 ? 168.218 161.619 160.072 1.00 104.87 ? 333 ASP A CB  1 
ATOM   2207 C  CG  . ASP A 1 333 ? 169.154 160.702 159.317 1.00 104.87 ? 333 ASP A CG  1 
ATOM   2208 O  OD1 . ASP A 1 333 ? 168.662 159.861 158.536 1.00 104.87 ? 333 ASP A OD1 1 
ATOM   2209 O  OD2 . ASP A 1 333 ? 170.383 160.822 159.504 1.00 104.87 ? 333 ASP A OD2 1 
ATOM   2210 N  N   . CYS A 1 334 ? 165.592 163.288 160.521 1.00 101.64 ? 334 CYS A N   1 
ATOM   2211 C  CA  . CYS A 1 334 ? 164.743 164.131 161.356 1.00 101.64 ? 334 CYS A CA  1 
ATOM   2212 C  C   . CYS A 1 334 ? 163.340 163.554 161.478 1.00 101.64 ? 334 CYS A C   1 
ATOM   2213 O  O   . CYS A 1 334 ? 162.788 163.465 162.584 1.00 101.64 ? 334 CYS A O   1 
ATOM   2214 C  CB  . CYS A 1 334 ? 164.695 165.543 160.774 1.00 101.64 ? 334 CYS A CB  1 
ATOM   2215 S  SG  . CYS A 1 334 ? 163.400 166.598 161.453 1.00 101.64 ? 334 CYS A SG  1 
ATOM   2216 N  N   . ILE A 1 335 ? 162.767 163.115 160.352 1.00 98.31  ? 335 ILE A N   1 
ATOM   2217 C  CA  . ILE A 1 335 ? 161.401 162.594 160.349 1.00 98.31  ? 335 ILE A CA  1 
ATOM   2218 C  C   . ILE A 1 335 ? 161.310 161.323 161.186 1.00 98.31  ? 335 ILE A C   1 
ATOM   2219 O  O   . ILE A 1 335 ? 160.434 161.193 162.054 1.00 98.31  ? 335 ILE A O   1 
ATOM   2220 C  CB  . ILE A 1 335 ? 160.927 162.356 158.903 1.00 98.31  ? 335 ILE A CB  1 
ATOM   2221 C  CG1 . ILE A 1 335 ? 160.508 163.676 158.256 1.00 98.31  ? 335 ILE A CG1 1 
ATOM   2222 C  CG2 . ILE A 1 335 ? 159.771 161.366 158.859 1.00 98.31  ? 335 ILE A CG2 1 
ATOM   2223 C  CD1 . ILE A 1 335 ? 159.281 164.296 158.876 1.00 98.31  ? 335 ILE A CD1 1 
ATOM   2224 N  N   . MET A 1 336 ? 162.238 160.383 160.972 1.00 102.10 ? 336 MET A N   1 
ATOM   2225 C  CA  . MET A 1 336 ? 162.141 159.108 161.675 1.00 102.10 ? 336 MET A CA  1 
ATOM   2226 C  C   . MET A 1 336 ? 162.483 159.255 163.155 1.00 102.10 ? 336 MET A C   1 
ATOM   2227 O  O   . MET A 1 336 ? 161.833 158.629 164.003 1.00 102.10 ? 336 MET A O   1 
ATOM   2228 C  CB  . MET A 1 336 ? 163.011 158.049 160.989 1.00 102.10 ? 336 MET A CB  1 
ATOM   2229 C  CG  . MET A 1 336 ? 164.514 158.237 161.075 1.00 102.10 ? 336 MET A CG  1 
ATOM   2230 S  SD  . MET A 1 336 ? 165.407 156.696 160.819 1.00 102.10 ? 336 MET A SD  1 
ATOM   2231 C  CE  . MET A 1 336 ? 167.024 157.159 161.421 1.00 102.10 ? 336 MET A CE  1 
ATOM   2232 N  N   . LEU A 1 337 ? 163.456 160.113 163.496 1.00 98.31  ? 337 LEU A N   1 
ATOM   2233 C  CA  . LEU A 1 337 ? 163.791 160.338 164.897 1.00 98.31  ? 337 LEU A CA  1 
ATOM   2234 C  C   . LEU A 1 337 ? 162.636 160.990 165.643 1.00 98.31  ? 337 LEU A C   1 
ATOM   2235 O  O   . LEU A 1 337 ? 162.281 160.556 166.747 1.00 98.31  ? 337 LEU A O   1 
ATOM   2236 C  CB  . LEU A 1 337 ? 165.048 161.200 165.000 1.00 98.31  ? 337 LEU A CB  1 
ATOM   2237 C  CG  . LEU A 1 337 ? 166.394 160.473 165.006 1.00 98.31  ? 337 LEU A CG  1 
ATOM   2238 C  CD1 . LEU A 1 337 ? 167.538 161.470 164.928 1.00 98.31  ? 337 LEU A CD1 1 
ATOM   2239 C  CD2 . LEU A 1 337 ? 166.526 159.606 166.243 1.00 98.31  ? 337 LEU A CD2 1 
ATOM   2240 N  N   . CYS A 1 338 ? 162.018 162.012 165.041 1.00 92.96  ? 338 CYS A N   1 
ATOM   2241 C  CA  . CYS A 1 338 ? 160.905 162.695 165.686 1.00 92.96  ? 338 CYS A CA  1 
ATOM   2242 C  C   . CYS A 1 338 ? 159.698 161.776 165.850 1.00 92.96  ? 338 CYS A C   1 
ATOM   2243 O  O   . CYS A 1 338 ? 159.078 161.742 166.924 1.00 92.96  ? 338 CYS A O   1 
ATOM   2244 C  CB  . CYS A 1 338 ? 160.541 163.936 164.878 1.00 92.96  ? 338 CYS A CB  1 
ATOM   2245 S  SG  . CYS A 1 338 ? 159.195 164.891 165.554 1.00 92.96  ? 338 CYS A SG  1 
ATOM   2246 N  N   . CYS A 1 339 ? 159.364 161.006 164.806 1.00 92.22  ? 339 CYS A N   1 
ATOM   2247 C  CA  . CYS A 1 339 ? 158.215 160.111 164.887 1.00 92.22  ? 339 CYS A CA  1 
ATOM   2248 C  C   . CYS A 1 339 ? 158.437 159.002 165.910 1.00 92.22  ? 339 CYS A C   1 
ATOM   2249 O  O   . CYS A 1 339 ? 157.525 158.672 166.679 1.00 92.22  ? 339 CYS A O   1 
ATOM   2250 C  CB  . CYS A 1 339 ? 157.913 159.520 163.511 1.00 92.22  ? 339 CYS A CB  1 
ATOM   2251 S  SG  . CYS A 1 339 ? 156.347 158.625 163.417 1.00 92.22  ? 339 CYS A SG  1 
ATOM   2252 N  N   . LEU A 1 340 ? 159.647 158.433 165.959 1.00 92.06  ? 340 LEU A N   1 
ATOM   2253 C  CA  . LEU A 1 340 ? 159.910 157.371 166.923 1.00 92.06  ? 340 LEU A CA  1 
ATOM   2254 C  C   . LEU A 1 340 ? 159.958 157.899 168.352 1.00 92.06  ? 340 LEU A C   1 
ATOM   2255 O  O   . LEU A 1 340 ? 159.535 157.197 169.281 1.00 92.06  ? 340 LEU A O   1 
ATOM   2256 C  CB  . LEU A 1 340 ? 161.208 156.653 166.562 1.00 92.06  ? 340 LEU A CB  1 
ATOM   2257 C  CG  . LEU A 1 340 ? 161.047 155.695 165.380 1.00 92.06  ? 340 LEU A CG  1 
ATOM   2258 C  CD1 . LEU A 1 340 ? 162.393 155.257 164.829 1.00 92.06  ? 340 LEU A CD1 1 
ATOM   2259 C  CD2 . LEU A 1 340 ? 160.211 154.491 165.783 1.00 92.06  ? 340 LEU A CD2 1 
ATOM   2260 N  N   . ASN A 1 341 ? 160.450 159.128 168.551 1.00 87.43  ? 341 ASN A N   1 
ATOM   2261 C  CA  . ASN A 1 341 ? 160.421 159.724 169.884 1.00 87.43  ? 341 ASN A CA  1 
ATOM   2262 C  C   . ASN A 1 341 ? 158.993 159.967 170.357 1.00 87.43  ? 341 ASN A C   1 
ATOM   2263 O  O   . ASN A 1 341 ? 158.659 159.679 171.517 1.00 87.43  ? 341 ASN A O   1 
ATOM   2264 C  CB  . ASN A 1 341 ? 161.222 161.023 169.893 1.00 87.43  ? 341 ASN A CB  1 
ATOM   2265 C  CG  . ASN A 1 341 ? 161.863 161.295 171.232 1.00 87.43  ? 341 ASN A CG  1 
ATOM   2266 O  OD1 . ASN A 1 341 ? 161.704 160.522 172.174 1.00 87.43  ? 341 ASN A OD1 1 
ATOM   2267 N  ND2 . ASN A 1 341 ? 162.600 162.393 171.324 1.00 87.43  ? 341 ASN A ND2 1 
ATOM   2268 N  N   . SER A 1 342 ? 158.131 160.475 169.468 1.00 85.30  ? 342 SER A N   1 
ATOM   2269 C  CA  . SER A 1 342 ? 156.724 160.644 169.825 1.00 85.30  ? 342 SER A CA  1 
ATOM   2270 C  C   . SER A 1 342 ? 156.069 159.302 170.129 1.00 85.30  ? 342 SER A C   1 
ATOM   2271 O  O   . SER A 1 342 ? 155.271 159.190 171.069 1.00 85.30  ? 342 SER A O   1 
ATOM   2272 C  CB  . SER A 1 342 ? 155.975 161.354 168.701 1.00 85.30  ? 342 SER A CB  1 
ATOM   2273 O  OG  . SER A 1 342 ? 155.612 160.438 167.683 1.00 85.30  ? 342 SER A OG  1 
ATOM   2274 N  N   . GLY A 1 343 ? 156.415 158.268 169.358 1.00 84.90  ? 343 GLY A N   1 
ATOM   2275 C  CA  . GLY A 1 343 ? 155.843 156.952 169.593 1.00 84.90  ? 343 GLY A CA  1 
ATOM   2276 C  C   . GLY A 1 343 ? 156.245 156.348 170.926 1.00 84.90  ? 343 GLY A C   1 
ATOM   2277 O  O   . GLY A 1 343 ? 155.407 155.784 171.638 1.00 84.90  ? 343 GLY A O   1 
ATOM   2278 N  N   . THR A 1 344 ? 157.524 156.461 171.291 1.00 83.36  ? 344 THR A N   1 
ATOM   2279 C  CA  . THR A 1 344 ? 157.935 155.878 172.564 1.00 83.36  ? 344 THR A CA  1 
ATOM   2280 C  C   . THR A 1 344 ? 157.415 156.692 173.750 1.00 83.36  ? 344 THR A C   1 
ATOM   2281 O  O   . THR A 1 344 ? 157.093 156.110 174.800 1.00 83.36  ? 344 THR A O   1 
ATOM   2282 C  CB  . THR A 1 344 ? 159.457 155.697 172.613 1.00 83.36  ? 344 THR A CB  1 
ATOM   2283 O  OG1 . THR A 1 344 ? 159.817 155.018 173.821 1.00 83.36  ? 344 THR A OG1 1 
ATOM   2284 C  CG2 . THR A 1 344 ? 160.191 157.017 172.545 1.00 83.36  ? 344 THR A CG2 1 
ATOM   2285 N  N   . SER A 1 345 ? 157.263 158.016 173.591 1.00 78.01  ? 345 SER A N   1 
ATOM   2286 C  CA  . SER A 1 345 ? 156.592 158.799 174.627 1.00 78.01  ? 345 SER A CA  1 
ATOM   2287 C  C   . SER A 1 345 ? 155.144 158.349 174.789 1.00 78.01  ? 345 SER A C   1 
ATOM   2288 O  O   . SER A 1 345 ? 154.656 158.187 175.915 1.00 78.01  ? 345 SER A O   1 
ATOM   2289 C  CB  . SER A 1 345 ? 156.660 160.291 174.293 1.00 78.01  ? 345 SER A CB  1 
ATOM   2290 O  OG  . SER A 1 345 ? 157.957 160.826 174.506 1.00 78.01  ? 345 SER A OG  1 
ATOM   2291 N  N   . PHE A 1 346 ? 154.468 158.083 173.667 1.00 76.66  ? 346 PHE A N   1 
ATOM   2292 C  CA  . PHE A 1 346 ? 153.085 157.620 173.688 1.00 76.66  ? 346 PHE A CA  1 
ATOM   2293 C  C   . PHE A 1 346 ? 152.959 156.267 174.386 1.00 76.66  ? 346 PHE A C   1 
ATOM   2294 O  O   . PHE A 1 346 ? 152.002 156.024 175.137 1.00 76.66  ? 346 PHE A O   1 
ATOM   2295 C  CB  . PHE A 1 346 ? 152.581 157.521 172.250 1.00 76.66  ? 346 PHE A CB  1 
ATOM   2296 C  CG  . PHE A 1 346 ? 151.116 157.733 172.104 1.00 76.66  ? 346 PHE A CG  1 
ATOM   2297 C  CD1 . PHE A 1 346 ? 150.524 158.868 172.610 1.00 76.66  ? 346 PHE A CD1 1 
ATOM   2298 C  CD2 . PHE A 1 346 ? 150.329 156.793 171.473 1.00 76.66  ? 346 PHE A CD2 1 
ATOM   2299 C  CE1 . PHE A 1 346 ? 149.170 159.072 172.482 1.00 76.66  ? 346 PHE A CE1 1 
ATOM   2300 C  CE2 . PHE A 1 346 ? 148.971 156.978 171.345 1.00 76.66  ? 346 PHE A CE2 1 
ATOM   2301 C  CZ  . PHE A 1 346 ? 148.386 158.124 171.845 1.00 76.66  ? 346 PHE A CZ  1 
ATOM   2302 N  N   . VAL A 1 347 ? 153.918 155.373 174.139 1.00 76.73  ? 347 VAL A N   1 
ATOM   2303 C  CA  . VAL A 1 347 ? 153.881 154.035 174.726 1.00 76.73  ? 347 VAL A CA  1 
ATOM   2304 C  C   . VAL A 1 347 ? 154.090 154.094 176.238 1.00 76.73  ? 347 VAL A C   1 
ATOM   2305 O  O   . VAL A 1 347 ? 153.370 153.435 177.010 1.00 76.73  ? 347 VAL A O   1 
ATOM   2306 C  CB  . VAL A 1 347 ? 154.924 153.150 174.021 1.00 76.73  ? 347 VAL A CB  1 
ATOM   2307 C  CG1 . VAL A 1 347 ? 155.303 151.948 174.863 1.00 76.73  ? 347 VAL A CG1 1 
ATOM   2308 C  CG2 . VAL A 1 347 ? 154.391 152.711 172.665 1.00 76.73  ? 347 VAL A CG2 1 
ATOM   2309 N  N   . ALA A 1 348 ? 155.060 154.900 176.690 1.00 75.26  ? 348 ALA A N   1 
ATOM   2310 C  CA  . ALA A 1 348 ? 155.240 155.101 178.127 1.00 75.26  ? 348 ALA A CA  1 
ATOM   2311 C  C   . ALA A 1 348 ? 154.006 155.743 178.754 1.00 75.26  ? 348 ALA A C   1 
ATOM   2312 O  O   . ALA A 1 348 ? 153.681 155.486 179.924 1.00 75.26  ? 348 ALA A O   1 
ATOM   2313 C  CB  . ALA A 1 348 ? 156.482 155.949 178.382 1.00 75.26  ? 348 ALA A CB  1 
ATOM   2314 N  N   . GLY A 1 349 ? 153.306 156.580 177.983 1.00 75.00  ? 349 GLY A N   1 
ATOM   2315 C  CA  . GLY A 1 349 ? 152.037 157.119 178.442 1.00 75.00  ? 349 GLY A CA  1 
ATOM   2316 C  C   . GLY A 1 349 ? 150.986 156.051 178.676 1.00 75.00  ? 349 GLY A C   1 
ATOM   2317 O  O   . GLY A 1 349 ? 150.302 156.066 179.706 1.00 75.00  ? 349 GLY A O   1 
ATOM   2318 N  N   . PHE A 1 350 ? 150.841 155.113 177.725 1.00 75.14  ? 350 PHE A N   1 
ATOM   2319 C  CA  . PHE A 1 350 ? 149.976 153.949 177.957 1.00 75.14  ? 350 PHE A CA  1 
ATOM   2320 C  C   . PHE A 1 350 ? 150.346 153.219 179.236 1.00 75.14  ? 350 PHE A C   1 
ATOM   2321 O  O   . PHE A 1 350 ? 149.468 152.872 180.033 1.00 75.14  ? 350 PHE A O   1 
ATOM   2322 C  CB  . PHE A 1 350 ? 150.003 152.935 176.809 1.00 75.14  ? 350 PHE A CB  1 
ATOM   2323 C  CG  . PHE A 1 350 ? 149.319 153.379 175.561 1.00 75.14  ? 350 PHE A CG  1 
ATOM   2324 C  CD1 . PHE A 1 350 ? 147.937 153.322 175.479 1.00 75.14  ? 350 PHE A CD1 1 
ATOM   2325 C  CD2 . PHE A 1 350 ? 150.043 153.723 174.435 1.00 75.14  ? 350 PHE A CD2 1 
ATOM   2326 C  CE1 . PHE A 1 350 ? 147.286 153.693 174.331 1.00 75.14  ? 350 PHE A CE1 1 
ATOM   2327 C  CE2 . PHE A 1 350 ? 149.397 154.086 173.270 1.00 75.14  ? 350 PHE A CE2 1 
ATOM   2328 C  CZ  . PHE A 1 350 ? 148.015 154.077 173.218 1.00 75.14  ? 350 PHE A CZ  1 
ATOM   2329 N  N   . ALA A 1 351 ? 151.644 152.979 179.445 1.00 75.99  ? 351 ALA A N   1 
ATOM   2330 C  CA  . ALA A 1 351 ? 152.072 152.168 180.585 1.00 75.99  ? 351 ALA A CA  1 
ATOM   2331 C  C   . ALA A 1 351 ? 151.718 152.833 181.913 1.00 75.99  ? 351 ALA A C   1 
ATOM   2332 O  O   . ALA A 1 351 ? 151.055 152.226 182.775 1.00 75.99  ? 351 ALA A O   1 
ATOM   2333 C  CB  . ALA A 1 351 ? 153.575 151.901 180.501 1.00 75.99  ? 351 ALA A CB  1 
ATOM   2334 N  N   . ILE A 1 352 ? 152.112 154.100 182.074 1.00 73.70  ? 352 ILE A N   1 
ATOM   2335 C  CA  . ILE A 1 352 ? 151.872 154.775 183.346 1.00 73.70  ? 352 ILE A CA  1 
ATOM   2336 C  C   . ILE A 1 352 ? 150.379 155.014 183.573 1.00 73.70  ? 352 ILE A C   1 
ATOM   2337 O  O   . ILE A 1 352 ? 149.874 154.834 184.694 1.00 73.70  ? 352 ILE A O   1 
ATOM   2338 C  CB  . ILE A 1 352 ? 152.706 156.066 183.422 1.00 73.70  ? 352 ILE A CB  1 
ATOM   2339 C  CG1 . ILE A 1 352 ? 154.162 155.695 183.655 1.00 73.70  ? 352 ILE A CG1 1 
ATOM   2340 C  CG2 . ILE A 1 352 ? 152.253 156.961 184.540 1.00 73.70  ? 352 ILE A CG2 1 
ATOM   2341 C  CD1 . ILE A 1 352 ? 155.136 156.830 183.696 1.00 73.70  ? 352 ILE A CD1 1 
ATOM   2342 N  N   . PHE A 1 353 ? 149.632 155.361 182.521 1.00 70.23  ? 353 PHE A N   1 
ATOM   2343 C  CA  . PHE A 1 353 ? 148.224 155.645 182.753 1.00 70.23  ? 353 PHE A CA  1 
ATOM   2344 C  C   . PHE A 1 353 ? 147.411 154.378 182.975 1.00 70.23  ? 353 PHE A C   1 
ATOM   2345 O  O   . PHE A 1 353 ? 146.440 154.408 183.737 1.00 70.23  ? 353 PHE A O   1 
ATOM   2346 C  CB  . PHE A 1 353 ? 147.655 156.478 181.617 1.00 70.23  ? 353 PHE A CB  1 
ATOM   2347 C  CG  . PHE A 1 353 ? 147.905 157.937 181.793 1.00 70.23  ? 353 PHE A CG  1 
ATOM   2348 C  CD1 . PHE A 1 353 ? 149.163 158.452 181.577 1.00 70.23  ? 353 PHE A CD1 1 
ATOM   2349 C  CD2 . PHE A 1 353 ? 146.905 158.782 182.238 1.00 70.23  ? 353 PHE A CD2 1 
ATOM   2350 C  CE1 . PHE A 1 353 ? 149.420 159.783 181.753 1.00 70.23  ? 353 PHE A CE1 1 
ATOM   2351 C  CE2 . PHE A 1 353 ? 147.155 160.120 182.419 1.00 70.23  ? 353 PHE A CE2 1 
ATOM   2352 C  CZ  . PHE A 1 353 ? 148.416 160.621 182.176 1.00 70.23  ? 353 PHE A CZ  1 
ATOM   2353 N  N   . SER A 1 354 ? 147.807 153.249 182.380 1.00 74.99  ? 354 SER A N   1 
ATOM   2354 C  CA  . SER A 1 354 ? 147.154 151.987 182.714 1.00 74.99  ? 354 SER A CA  1 
ATOM   2355 C  C   . SER A 1 354 ? 147.422 151.598 184.162 1.00 74.99  ? 354 SER A C   1 
ATOM   2356 O  O   . SER A 1 354 ? 146.516 151.130 184.868 1.00 74.99  ? 354 SER A O   1 
ATOM   2357 C  CB  . SER A 1 354 ? 147.626 150.880 181.773 1.00 74.99  ? 354 SER A CB  1 
ATOM   2358 O  OG  . SER A 1 354 ? 149.036 150.903 181.624 1.00 74.99  ? 354 SER A OG  1 
ATOM   2359 N  N   . VAL A 1 355 ? 148.660 151.804 184.628 1.00 72.15  ? 355 VAL A N   1 
ATOM   2360 C  CA  . VAL A 1 355 ? 149.005 151.434 186.002 1.00 72.15  ? 355 VAL A CA  1 
ATOM   2361 C  C   . VAL A 1 355 ? 148.222 152.281 187.004 1.00 72.15  ? 355 VAL A C   1 
ATOM   2362 O  O   . VAL A 1 355 ? 147.648 151.762 187.973 1.00 72.15  ? 355 VAL A O   1 
ATOM   2363 C  CB  . VAL A 1 355 ? 150.523 151.550 186.218 1.00 72.15  ? 355 VAL A CB  1 
ATOM   2364 C  CG1 . VAL A 1 355 ? 150.850 151.541 187.688 1.00 72.15  ? 355 VAL A CG1 1 
ATOM   2365 C  CG2 . VAL A 1 355 ? 151.232 150.418 185.513 1.00 72.15  ? 355 VAL A CG2 1 
ATOM   2366 N  N   . LEU A 1 356 ? 148.156 153.595 186.774 1.00 74.03  ? 356 LEU A N   1 
ATOM   2367 C  CA  . LEU A 1 356 ? 147.409 154.426 187.715 1.00 74.03  ? 356 LEU A CA  1 
ATOM   2368 C  C   . LEU A 1 356 ? 145.901 154.278 187.543 1.00 74.03  ? 356 LEU A C   1 
ATOM   2369 O  O   . LEU A 1 356 ? 145.155 154.573 188.482 1.00 74.03  ? 356 LEU A O   1 
ATOM   2370 C  CB  . LEU A 1 356 ? 147.847 155.889 187.614 1.00 74.03  ? 356 LEU A CB  1 
ATOM   2371 C  CG  . LEU A 1 356 ? 147.712 156.733 186.353 1.00 74.03  ? 356 LEU A CG  1 
ATOM   2372 C  CD1 . LEU A 1 356 ? 146.367 157.422 186.290 1.00 74.03  ? 356 LEU A CD1 1 
ATOM   2373 C  CD2 . LEU A 1 356 ? 148.828 157.749 186.331 1.00 74.03  ? 356 LEU A CD2 1 
ATOM   2374 N  N   . GLY A 1 357 ? 145.433 153.799 186.388 1.00 77.94  ? 357 GLY A N   1 
ATOM   2375 C  CA  . GLY A 1 357 ? 144.049 153.372 186.293 1.00 77.94  ? 357 GLY A CA  1 
ATOM   2376 C  C   . GLY A 1 357 ? 143.761 152.179 187.182 1.00 77.94  ? 357 GLY A C   1 
ATOM   2377 O  O   . GLY A 1 357 ? 142.705 152.107 187.817 1.00 77.94  ? 357 GLY A O   1 
ATOM   2378 N  N   . PHE A 1 358 ? 144.704 151.235 187.255 1.00 83.34  ? 358 PHE A N   1 
ATOM   2379 C  CA  . PHE A 1 358 ? 144.568 150.141 188.217 1.00 83.34  ? 358 PHE A CA  1 
ATOM   2380 C  C   . PHE A 1 358 ? 144.592 150.658 189.650 1.00 83.34  ? 358 PHE A C   1 
ATOM   2381 O  O   . PHE A 1 358 ? 143.878 150.139 190.518 1.00 83.34  ? 358 PHE A O   1 
ATOM   2382 C  CB  . PHE A 1 358 ? 145.674 149.105 188.026 1.00 83.34  ? 358 PHE A CB  1 
ATOM   2383 C  CG  . PHE A 1 358 ? 145.870 148.203 189.218 1.00 83.34  ? 358 PHE A CG  1 
ATOM   2384 C  CD1 . PHE A 1 358 ? 144.946 147.217 189.511 1.00 83.34  ? 358 PHE A CD1 1 
ATOM   2385 C  CD2 . PHE A 1 358 ? 146.968 148.348 190.051 1.00 83.34  ? 358 PHE A CD2 1 
ATOM   2386 C  CE1 . PHE A 1 358 ? 145.114 146.389 190.601 1.00 83.34  ? 358 PHE A CE1 1 
ATOM   2387 C  CE2 . PHE A 1 358 ? 147.142 147.520 191.139 1.00 83.34  ? 358 PHE A CE2 1 
ATOM   2388 C  CZ  . PHE A 1 358 ? 146.212 146.541 191.415 1.00 83.34  ? 358 PHE A CZ  1 
ATOM   2389 N  N   . MET A 1 359 ? 145.440 151.652 189.921 1.00 81.17  ? 359 MET A N   1 
ATOM   2390 C  CA  . MET A 1 359 ? 145.511 152.239 191.259 1.00 81.17  ? 359 MET A CA  1 
ATOM   2391 C  C   . MET A 1 359 ? 144.180 152.875 191.650 1.00 81.17  ? 359 MET A C   1 
ATOM   2392 O  O   . MET A 1 359 ? 143.686 152.684 192.768 1.00 81.17  ? 359 MET A O   1 
ATOM   2393 C  CB  . MET A 1 359 ? 146.639 153.270 191.315 1.00 81.17  ? 359 MET A CB  1 
ATOM   2394 C  CG  . MET A 1 359 ? 147.999 152.692 191.670 1.00 81.17  ? 359 MET A CG  1 
ATOM   2395 S  SD  . MET A 1 359 ? 149.311 153.931 191.647 1.00 81.17  ? 359 MET A SD  1 
ATOM   2396 C  CE  . MET A 1 359 ? 149.335 154.442 193.361 1.00 81.17  ? 359 MET A CE  1 
ATOM   2397 N  N   . ALA A 1 360 ? 143.572 153.617 190.724 1.00 82.90  ? 360 ALA A N   1 
ATOM   2398 C  CA  . ALA A 1 360 ? 142.266 154.209 190.986 1.00 82.90  ? 360 ALA A CA  1 
ATOM   2399 C  C   . ALA A 1 360 ? 141.173 153.153 191.074 1.00 82.90  ? 360 ALA A C   1 
ATOM   2400 O  O   . ALA A 1 360 ? 140.169 153.361 191.763 1.00 82.90  ? 360 ALA A O   1 
ATOM   2401 C  CB  . ALA A 1 360 ? 141.925 155.231 189.907 1.00 82.90  ? 360 ALA A CB  1 
ATOM   2402 N  N   . TYR A 1 361 ? 141.335 152.029 190.373 1.00 85.07  ? 361 TYR A N   1 
ATOM   2403 C  CA  . TYR A 1 361 ? 140.368 150.941 190.486 1.00 85.07  ? 361 TYR A CA  1 
ATOM   2404 C  C   . TYR A 1 361 ? 140.431 150.290 191.862 1.00 85.07  ? 361 TYR A C   1 
ATOM   2405 O  O   . TYR A 1 361 ? 139.394 150.018 192.478 1.00 85.07  ? 361 TYR A O   1 
ATOM   2406 C  CB  . TYR A 1 361 ? 140.615 149.907 189.389 1.00 85.07  ? 361 TYR A CB  1 
ATOM   2407 C  CG  . TYR A 1 361 ? 140.029 148.543 189.679 1.00 85.07  ? 361 TYR A CG  1 
ATOM   2408 C  CD1 . TYR A 1 361 ? 138.656 148.333 189.645 1.00 85.07  ? 361 TYR A CD1 1 
ATOM   2409 C  CD2 . TYR A 1 361 ? 140.850 147.462 189.973 1.00 85.07  ? 361 TYR A CD2 1 
ATOM   2410 C  CE1 . TYR A 1 361 ? 138.117 147.085 189.905 1.00 85.07  ? 361 TYR A CE1 1 
ATOM   2411 C  CE2 . TYR A 1 361 ? 140.321 146.212 190.233 1.00 85.07  ? 361 TYR A CE2 1 
ATOM   2412 C  CZ  . TYR A 1 361 ? 138.956 146.030 190.198 1.00 85.07  ? 361 TYR A CZ  1 
ATOM   2413 O  OH  . TYR A 1 361 ? 138.428 144.787 190.457 1.00 85.07  ? 361 TYR A OH  1 
ATOM   2414 N  N   . GLU A 1 362 ? 141.641 150.028 192.358 1.00 89.98  ? 362 GLU A N   1 
ATOM   2415 C  CA  . GLU A 1 362 ? 141.776 149.386 193.661 1.00 89.98  ? 362 GLU A CA  1 
ATOM   2416 C  C   . GLU A 1 362 ? 141.484 150.345 194.808 1.00 89.98  ? 362 GLU A C   1 
ATOM   2417 O  O   . GLU A 1 362 ? 141.167 149.888 195.910 1.00 89.98  ? 362 GLU A O   1 
ATOM   2418 C  CB  . GLU A 1 362 ? 143.170 148.772 193.821 1.00 89.98  ? 362 GLU A CB  1 
ATOM   2419 C  CG  . GLU A 1 362 ? 144.292 149.764 194.046 1.00 89.98  ? 362 GLU A CG  1 
ATOM   2420 C  CD  . GLU A 1 362 ? 145.552 149.106 194.566 1.00 89.98  ? 362 GLU A CD  1 
ATOM   2421 O  OE1 . GLU A 1 362 ? 145.707 147.883 194.367 1.00 89.98  ? 362 GLU A OE1 1 
ATOM   2422 O  OE2 . GLU A 1 362 ? 146.389 149.809 195.171 1.00 89.98  ? 362 GLU A OE2 1 
ATOM   2423 N  N   . GLN A 1 363 ? 141.579 151.655 194.581 1.00 90.67  ? 363 GLN A N   1 
ATOM   2424 C  CA  . GLN A 1 363 ? 141.060 152.609 195.547 1.00 90.67  ? 363 GLN A CA  1 
ATOM   2425 C  C   . GLN A 1 363 ? 139.610 152.945 195.206 1.00 90.67  ? 363 GLN A C   1 
ATOM   2426 O  O   . GLN A 1 363 ? 139.029 152.420 194.254 1.00 90.67  ? 363 GLN A O   1 
ATOM   2427 C  CB  . GLN A 1 363 ? 141.917 153.874 195.587 1.00 90.67  ? 363 GLN A CB  1 
ATOM   2428 C  CG  . GLN A 1 363 ? 143.388 153.635 195.849 1.00 90.67  ? 363 GLN A CG  1 
ATOM   2429 C  CD  . GLN A 1 363 ? 144.134 154.913 196.160 1.00 90.67  ? 363 GLN A CD  1 
ATOM   2430 O  OE1 . GLN A 1 363 ? 143.560 155.865 196.681 1.00 90.67  ? 363 GLN A OE1 1 
ATOM   2431 N  NE2 . GLN A 1 363 ? 145.419 154.943 195.835 1.00 90.67  ? 363 GLN A NE2 1 
ATOM   2432 N  N   . GLY A 1 364 ? 139.010 153.824 196.001 1.00 93.13  ? 364 GLY A N   1 
ATOM   2433 C  CA  . GLY A 1 364 ? 137.683 154.321 195.697 1.00 93.13  ? 364 GLY A CA  1 
ATOM   2434 C  C   . GLY A 1 364 ? 137.726 155.710 195.095 1.00 93.13  ? 364 GLY A C   1 
ATOM   2435 O  O   . GLY A 1 364 ? 136.709 156.232 194.627 1.00 93.13  ? 364 GLY A O   1 
ATOM   2436 N  N   . VAL A 1 365 ? 138.909 156.315 195.106 1.00 88.57  ? 365 VAL A N   1 
ATOM   2437 C  CA  . VAL A 1 365 ? 139.116 157.674 194.614 1.00 88.57  ? 365 VAL A CA  1 
ATOM   2438 C  C   . VAL A 1 365 ? 139.101 157.612 193.088 1.00 88.57  ? 365 VAL A C   1 
ATOM   2439 O  O   . VAL A 1 365 ? 139.475 156.578 192.514 1.00 88.57  ? 365 VAL A O   1 
ATOM   2440 C  CB  . VAL A 1 365 ? 140.422 158.261 195.190 1.00 88.57  ? 365 VAL A CB  1 
ATOM   2441 C  CG1 . VAL A 1 365 ? 141.661 157.625 194.565 1.00 88.57  ? 365 VAL A CG1 1 
ATOM   2442 C  CG2 . VAL A 1 365 ? 140.462 159.780 195.111 1.00 88.57  ? 365 VAL A CG2 1 
ATOM   2443 N  N   . PRO A 1 366 ? 138.620 158.647 192.384 1.00 91.48  ? 366 PRO A N   1 
ATOM   2444 C  CA  . PRO A 1 366 ? 138.707 158.623 190.918 1.00 91.48  ? 366 PRO A CA  1 
ATOM   2445 C  C   . PRO A 1 366 ? 140.120 158.812 190.391 1.00 91.48  ? 366 PRO A C   1 
ATOM   2446 O  O   . PRO A 1 366 ? 141.064 159.038 191.154 1.00 91.48  ? 366 PRO A O   1 
ATOM   2447 C  CB  . PRO A 1 366 ? 137.788 159.774 190.489 1.00 91.48  ? 366 PRO A CB  1 
ATOM   2448 C  CG  . PRO A 1 366 ? 137.684 160.650 191.677 1.00 91.48  ? 366 PRO A CG  1 
ATOM   2449 C  CD  . PRO A 1 366 ? 137.727 159.722 192.850 1.00 91.48  ? 366 PRO A CD  1 
ATOM   2450 N  N   . ILE A 1 367 ? 140.254 158.721 189.066 1.00 85.91  ? 367 ILE A N   1 
ATOM   2451 C  CA  . ILE A 1 367 ? 141.558 158.679 188.412 1.00 85.91  ? 367 ILE A CA  1 
ATOM   2452 C  C   . ILE A 1 367 ? 142.270 160.023 188.532 1.00 85.91  ? 367 ILE A C   1 
ATOM   2453 O  O   . ILE A 1 367 ? 143.507 160.078 188.565 1.00 85.91  ? 367 ILE A O   1 
ATOM   2454 C  CB  . ILE A 1 367 ? 141.383 158.244 186.939 1.00 85.91  ? 367 ILE A CB  1 
ATOM   2455 C  CG1 . ILE A 1 367 ? 140.697 156.877 186.836 1.00 85.91  ? 367 ILE A CG1 1 
ATOM   2456 C  CG2 . ILE A 1 367 ? 142.712 158.130 186.224 1.00 85.91  ? 367 ILE A CG2 1 
ATOM   2457 C  CD1 . ILE A 1 367 ? 139.196 156.923 186.561 1.00 85.91  ? 367 ILE A CD1 1 
ATOM   2458 N  N   . ALA A 1 368 ? 141.505 161.116 188.637 1.00 85.17  ? 368 ALA A N   1 
ATOM   2459 C  CA  . ALA A 1 368 ? 142.070 162.462 188.557 1.00 85.17  ? 368 ALA A CA  1 
ATOM   2460 C  C   . ALA A 1 368 ? 143.041 162.745 189.696 1.00 85.17  ? 368 ALA A C   1 
ATOM   2461 O  O   . ALA A 1 368 ? 144.085 163.372 189.484 1.00 85.17  ? 368 ALA A O   1 
ATOM   2462 C  CB  . ALA A 1 368 ? 140.947 163.499 188.545 1.00 85.17  ? 368 ALA A CB  1 
ATOM   2463 N  N   . GLU A 1 369 ? 142.726 162.288 190.909 1.00 87.17  ? 369 GLU A N   1 
ATOM   2464 C  CA  . GLU A 1 369 ? 143.620 162.464 192.054 1.00 87.17  ? 369 GLU A CA  1 
ATOM   2465 C  C   . GLU A 1 369 ? 143.860 161.096 192.689 1.00 87.17  ? 369 GLU A C   1 
ATOM   2466 O  O   . GLU A 1 369 ? 143.216 160.723 193.670 1.00 87.17  ? 369 GLU A O   1 
ATOM   2467 C  CB  . GLU A 1 369 ? 143.043 163.465 193.051 1.00 87.17  ? 369 GLU A CB  1 
ATOM   2468 C  CG  . GLU A 1 369 ? 144.039 163.935 194.098 1.00 87.17  ? 369 GLU A CG  1 
ATOM   2469 C  CD  . GLU A 1 369 ? 145.217 164.681 193.491 1.00 87.17  ? 369 GLU A CD  1 
ATOM   2470 O  OE1 . GLU A 1 369 ? 145.006 165.452 192.530 1.00 87.17  ? 369 GLU A OE1 1 
ATOM   2471 O  OE2 . GLU A 1 369 ? 146.354 164.497 193.976 1.00 87.17  ? 369 GLU A OE2 1 
ATOM   2472 N  N   . VAL A 1 370 ? 144.813 160.356 192.126 1.00 79.91  ? 370 VAL A N   1 
ATOM   2473 C  CA  . VAL A 1 370 ? 145.281 159.109 192.722 1.00 79.91  ? 370 VAL A CA  1 
ATOM   2474 C  C   . VAL A 1 370 ? 146.791 159.069 192.869 1.00 79.91  ? 370 VAL A C   1 
ATOM   2475 O  O   . VAL A 1 370 ? 147.315 158.283 193.681 1.00 79.91  ? 370 VAL A O   1 
ATOM   2476 C  CB  . VAL A 1 370 ? 144.782 157.895 191.898 1.00 79.91  ? 370 VAL A CB  1 
ATOM   2477 C  CG1 . VAL A 1 370 ? 145.573 157.738 190.613 1.00 79.91  ? 370 VAL A CG1 1 
ATOM   2478 C  CG2 . VAL A 1 370 ? 144.794 156.610 192.720 1.00 79.91  ? 370 VAL A CG2 1 
ATOM   2479 N  N   . ALA A 1 371 ? 147.529 159.907 192.155 1.00 78.28  ? 371 ALA A N   1 
ATOM   2480 C  CA  . ALA A 1 371 ? 148.969 160.032 192.279 1.00 78.28  ? 371 ALA A CA  1 
ATOM   2481 C  C   . ALA A 1 371 ? 149.306 161.463 192.687 1.00 78.28  ? 371 ALA A C   1 
ATOM   2482 O  O   . ALA A 1 371 ? 148.428 162.258 193.031 1.00 78.28  ? 371 ALA A O   1 
ATOM   2483 C  CB  . ALA A 1 371 ? 149.659 159.631 190.977 1.00 78.28  ? 371 ALA A CB  1 
ATOM   2484 N  N   . GLU A 1 372 ? 150.598 161.784 192.654 1.00 78.16  ? 372 GLU A N   1 
ATOM   2485 C  CA  . GLU A 1 372 ? 151.046 163.084 193.140 1.00 78.16  ? 372 GLU A CA  1 
ATOM   2486 C  C   . GLU A 1 372 ? 150.751 164.194 192.138 1.00 78.16  ? 372 GLU A C   1 
ATOM   2487 O  O   . GLU A 1 372 ? 150.535 165.345 192.535 1.00 78.16  ? 372 GLU A O   1 
ATOM   2488 C  CB  . GLU A 1 372 ? 152.539 163.027 193.458 1.00 78.16  ? 372 GLU A CB  1 
ATOM   2489 C  CG  . GLU A 1 372 ? 153.084 164.263 194.143 1.00 78.16  ? 372 GLU A CG  1 
ATOM   2490 C  CD  . GLU A 1 372 ? 154.446 164.032 194.742 1.00 78.16  ? 372 GLU A CD  1 
ATOM   2491 O  OE1 . GLU A 1 372 ? 155.224 163.246 194.164 1.00 78.16  ? 372 GLU A OE1 1 
ATOM   2492 O  OE2 . GLU A 1 372 ? 154.743 164.641 195.790 1.00 78.16  ? 372 GLU A OE2 1 
ATOM   2493 N  N   . SER A 1 373 ? 150.793 163.876 190.838 1.00 72.40  ? 373 SER A N   1 
ATOM   2494 C  CA  . SER A 1 373 ? 150.671 164.808 189.712 1.00 72.40  ? 373 SER A CA  1 
ATOM   2495 C  C   . SER A 1 373 ? 151.817 165.818 189.660 1.00 72.40  ? 373 SER A C   1 
ATOM   2496 O  O   . SER A 1 373 ? 151.803 166.735 188.834 1.00 72.40  ? 373 SER A O   1 
ATOM   2497 C  CB  . SER A 1 373 ? 149.323 165.545 189.723 1.00 72.40  ? 373 SER A CB  1 
ATOM   2498 O  OG  . SER A 1 373 ? 148.255 164.660 190.004 1.00 72.40  ? 373 SER A OG  1 
ATOM   2499 N  N   . GLY A 1 374 ? 152.806 165.667 190.536 1.00 71.35  ? 374 GLY A N   1 
ATOM   2500 C  CA  . GLY A 1 374 ? 154.052 166.380 190.427 1.00 71.35  ? 374 GLY A CA  1 
ATOM   2501 C  C   . GLY A 1 374 ? 155.048 165.508 189.698 1.00 71.35  ? 374 GLY A C   1 
ATOM   2502 O  O   . GLY A 1 374 ? 154.721 164.395 189.275 1.00 71.35  ? 374 GLY A O   1 
ATOM   2503 N  N   . PRO A 1 375 ? 156.280 165.980 189.527 1.00 68.43  ? 375 PRO A N   1 
ATOM   2504 C  CA  . PRO A 1 375 ? 157.273 165.205 188.756 1.00 68.43  ? 375 PRO A CA  1 
ATOM   2505 C  C   . PRO A 1 375 ? 157.857 164.034 189.542 1.00 68.43  ? 375 PRO A C   1 
ATOM   2506 O  O   . PRO A 1 375 ? 159.069 163.905 189.720 1.00 68.43  ? 375 PRO A O   1 
ATOM   2507 C  CB  . PRO A 1 375 ? 158.320 166.268 188.401 1.00 68.43  ? 375 PRO A CB  1 
ATOM   2508 C  CG  . PRO A 1 375 ? 158.164 167.341 189.383 1.00 68.43  ? 375 PRO A CG  1 
ATOM   2509 C  CD  . PRO A 1 375 ? 156.786 167.294 189.951 1.00 68.43  ? 375 PRO A CD  1 
ATOM   2510 N  N   . GLY A 1 376 ? 156.975 163.155 190.009 1.00 65.98  ? 376 GLY A N   1 
ATOM   2511 C  CA  . GLY A 1 376 ? 157.357 161.929 190.671 1.00 65.98  ? 376 GLY A CA  1 
ATOM   2512 C  C   . GLY A 1 376 ? 156.408 160.815 190.289 1.00 65.98  ? 376 GLY A C   1 
ATOM   2513 O  O   . GLY A 1 376 ? 156.381 159.760 190.928 1.00 65.98  ? 376 GLY A O   1 
ATOM   2514 N  N   . LEU A 1 377 ? 155.614 161.058 189.243 1.00 64.49  ? 377 LEU A N   1 
ATOM   2515 C  CA  . LEU A 1 377 ? 154.671 160.055 188.757 1.00 64.49  ? 377 LEU A CA  1 
ATOM   2516 C  C   . LEU A 1 377 ? 155.391 158.821 188.233 1.00 64.49  ? 377 LEU A C   1 
ATOM   2517 O  O   . LEU A 1 377 ? 154.951 157.689 188.468 1.00 64.49  ? 377 LEU A O   1 
ATOM   2518 C  CB  . LEU A 1 377 ? 153.787 160.660 187.671 1.00 64.49  ? 377 LEU A CB  1 
ATOM   2519 C  CG  . LEU A 1 377 ? 152.772 159.726 187.021 1.00 64.49  ? 377 LEU A CG  1 
ATOM   2520 C  CD1 . LEU A 1 377 ? 151.810 159.178 188.041 1.00 64.49  ? 377 LEU A CD1 1 
ATOM   2521 C  CD2 . LEU A 1 377 ? 152.033 160.455 185.932 1.00 64.49  ? 377 LEU A CD2 1 
ATOM   2522 N  N   . ALA A 1 378 ? 156.504 159.016 187.524 1.00 67.34  ? 378 ALA A N   1 
ATOM   2523 C  CA  . ALA A 1 378 ? 157.313 157.886 187.088 1.00 67.34  ? 378 ALA A CA  1 
ATOM   2524 C  C   . ALA A 1 378 ? 157.971 157.165 188.254 1.00 67.34  ? 378 ALA A C   1 
ATOM   2525 O  O   . ALA A 1 378 ? 158.411 156.024 188.091 1.00 67.34  ? 378 ALA A O   1 
ATOM   2526 C  CB  . ALA A 1 378 ? 158.379 158.349 186.099 1.00 67.34  ? 378 ALA A CB  1 
ATOM   2527 N  N   . PHE A 1 379 ? 158.060 157.809 189.415 1.00 63.39  ? 379 PHE A N   1 
ATOM   2528 C  CA  . PHE A 1 379 ? 158.551 157.188 190.633 1.00 63.39  ? 379 PHE A CA  1 
ATOM   2529 C  C   . PHE A 1 379 ? 157.422 156.713 191.532 1.00 63.39  ? 379 PHE A C   1 
ATOM   2530 O  O   . PHE A 1 379 ? 157.668 156.383 192.695 1.00 63.39  ? 379 PHE A O   1 
ATOM   2531 C  CB  . PHE A 1 379 ? 159.447 158.164 191.391 1.00 63.39  ? 379 PHE A CB  1 
ATOM   2532 C  CG  . PHE A 1 379 ? 160.753 158.419 190.714 1.00 63.39  ? 379 PHE A CG  1 
ATOM   2533 C  CD1 . PHE A 1 379 ? 161.668 157.399 190.544 1.00 63.39  ? 379 PHE A CD1 1 
ATOM   2534 C  CD2 . PHE A 1 379 ? 161.056 159.676 190.227 1.00 63.39  ? 379 PHE A CD2 1 
ATOM   2535 C  CE1 . PHE A 1 379 ? 162.870 157.630 189.916 1.00 63.39  ? 379 PHE A CE1 1 
ATOM   2536 C  CE2 . PHE A 1 379 ? 162.254 159.914 189.596 1.00 63.39  ? 379 PHE A CE2 1 
ATOM   2537 C  CZ  . PHE A 1 379 ? 163.163 158.890 189.440 1.00 63.39  ? 379 PHE A CZ  1 
ATOM   2538 N  N   . ILE A 1 380 ? 156.190 156.681 191.022 1.00 63.82  ? 380 ILE A N   1 
ATOM   2539 C  CA  . ILE A 1 380 ? 155.033 156.182 191.753 1.00 63.82  ? 380 ILE A CA  1 
ATOM   2540 C  C   . ILE A 1 380 ? 154.324 155.072 190.981 1.00 63.82  ? 380 ILE A C   1 
ATOM   2541 O  O   . ILE A 1 380 ? 154.038 154.004 191.530 1.00 63.82  ? 380 ILE A O   1 
ATOM   2542 C  CB  . ILE A 1 380 ? 154.055 157.326 192.099 1.00 63.82  ? 380 ILE A CB  1 
ATOM   2543 C  CG1 . ILE A 1 380 ? 154.605 158.137 193.268 1.00 63.82  ? 380 ILE A CG1 1 
ATOM   2544 C  CG2 . ILE A 1 380 ? 152.675 156.791 192.447 1.00 63.82  ? 380 ILE A CG2 1 
ATOM   2545 C  CD1 . ILE A 1 380 ? 154.101 159.553 193.309 1.00 63.82  ? 380 ILE A CD1 1 
ATOM   2546 N  N   . ALA A 1 381 ? 154.048 155.302 189.695 1.00 66.09  ? 381 ALA A N   1 
ATOM   2547 C  CA  . ALA A 1 381 ? 153.373 154.286 188.893 1.00 66.09  ? 381 ALA A CA  1 
ATOM   2548 C  C   . ALA A 1 381 ? 154.296 153.113 188.583 1.00 66.09  ? 381 ALA A C   1 
ATOM   2549 O  O   . ALA A 1 381 ? 153.903 151.951 188.727 1.00 66.09  ? 381 ALA A O   1 
ATOM   2550 C  CB  . ALA A 1 381 ? 152.836 154.907 187.605 1.00 66.09  ? 381 ALA A CB  1 
ATOM   2551 N  N   . TYR A 1 382 ? 155.521 153.395 188.142 1.00 69.56  ? 382 TYR A N   1 
ATOM   2552 C  CA  . TYR A 1 382 ? 156.491 152.328 187.899 1.00 69.56  ? 382 TYR A CA  1 
ATOM   2553 C  C   . TYR A 1 382 ? 156.875 151.501 189.128 1.00 69.56  ? 382 TYR A C   1 
ATOM   2554 O  O   . TYR A 1 382 ? 156.949 150.269 188.988 1.00 69.56  ? 382 TYR A O   1 
ATOM   2555 C  CB  . TYR A 1 382 ? 157.715 152.917 187.182 1.00 69.56  ? 382 TYR A CB  1 
ATOM   2556 C  CG  . TYR A 1 382 ? 157.486 153.245 185.725 1.00 69.56  ? 382 TYR A CG  1 
ATOM   2557 C  CD1 . TYR A 1 382 ? 156.432 152.678 185.025 1.00 69.56  ? 382 TYR A CD1 1 
ATOM   2558 C  CD2 . TYR A 1 382 ? 158.277 154.177 185.070 1.00 69.56  ? 382 TYR A CD2 1 
ATOM   2559 C  CE1 . TYR A 1 382 ? 156.236 152.966 183.689 1.00 69.56  ? 382 TYR A CE1 1 
ATOM   2560 C  CE2 . TYR A 1 382 ? 158.075 154.484 183.744 1.00 69.56  ? 382 TYR A CE2 1 
ATOM   2561 C  CZ  . TYR A 1 382 ? 157.049 153.882 183.061 1.00 69.56  ? 382 TYR A CZ  1 
ATOM   2562 O  OH  . TYR A 1 382 ? 156.841 154.202 181.741 1.00 69.56  ? 382 TYR A OH  1 
ATOM   2563 N  N   . PRO A 1 383 ? 157.139 152.061 190.319 1.00 66.14  ? 383 PRO A N   1 
ATOM   2564 C  CA  . PRO A 1 383 ? 157.308 151.184 191.491 1.00 66.14  ? 383 PRO A CA  1 
ATOM   2565 C  C   . PRO A 1 383 ? 156.050 150.429 191.889 1.00 66.14  ? 383 PRO A C   1 
ATOM   2566 O  O   . PRO A 1 383 ? 156.161 149.396 192.560 1.00 66.14  ? 383 PRO A O   1 
ATOM   2567 C  CB  . PRO A 1 383 ? 157.751 152.151 192.593 1.00 66.14  ? 383 PRO A CB  1 
ATOM   2568 C  CG  . PRO A 1 383 ? 158.384 153.253 191.862 1.00 66.14  ? 383 PRO A CG  1 
ATOM   2569 C  CD  . PRO A 1 383 ? 157.533 153.439 190.658 1.00 66.14  ? 383 PRO A CD  1 
ATOM   2570 N  N   . LYS A 1 384 ? 154.864 150.904 191.507 1.00 67.89  ? 384 LYS A N   1 
ATOM   2571 C  CA  . LYS A 1 384 ? 153.651 150.129 191.748 1.00 67.89  ? 384 LYS A CA  1 
ATOM   2572 C  C   . LYS A 1 384 ? 153.540 148.969 190.767 1.00 67.89  ? 384 LYS A C   1 
ATOM   2573 O  O   . LYS A 1 384 ? 153.088 147.879 191.135 1.00 67.89  ? 384 LYS A O   1 
ATOM   2574 C  CB  . LYS A 1 384 ? 152.424 151.036 191.652 1.00 67.89  ? 384 LYS A CB  1 
ATOM   2575 C  CG  . LYS A 1 384 ? 151.085 150.323 191.749 1.00 67.89  ? 384 LYS A CG  1 
ATOM   2576 C  CD  . LYS A 1 384 ? 150.928 149.618 193.082 1.00 67.89  ? 384 LYS A CD  1 
ATOM   2577 C  CE  . LYS A 1 384 ? 149.473 149.274 193.342 1.00 67.89  ? 384 LYS A CE  1 
ATOM   2578 N  NZ  . LYS A 1 384 ? 149.159 149.209 194.795 1.00 67.89  ? 384 LYS A NZ  1 
ATOM   2579 N  N   . ALA A 1 385 ? 153.949 149.187 189.515 1.00 71.32  ? 385 ALA A N   1 
ATOM   2580 C  CA  . ALA A 1 385 ? 153.836 148.148 188.496 1.00 71.32  ? 385 ALA A CA  1 
ATOM   2581 C  C   . ALA A 1 385 ? 154.776 146.985 188.777 1.00 71.32  ? 385 ALA A C   1 
ATOM   2582 O  O   . ALA A 1 385 ? 154.397 145.821 188.608 1.00 71.32  ? 385 ALA A O   1 
ATOM   2583 C  CB  . ALA A 1 385 ? 154.115 148.735 187.114 1.00 71.32  ? 385 ALA A CB  1 
ATOM   2584 N  N   . VAL A 1 386 ? 156.004 147.276 189.214 1.00 74.59  ? 386 VAL A N   1 
ATOM   2585 C  CA  . VAL A 1 386 ? 156.973 146.216 189.458 1.00 74.59  ? 386 VAL A CA  1 
ATOM   2586 C  C   . VAL A 1 386 ? 156.661 145.394 190.696 1.00 74.59  ? 386 VAL A C   1 
ATOM   2587 O  O   . VAL A 1 386 ? 157.273 144.342 190.887 1.00 74.59  ? 386 VAL A O   1 
ATOM   2588 C  CB  . VAL A 1 386 ? 158.405 146.774 189.572 1.00 74.59  ? 386 VAL A CB  1 
ATOM   2589 C  CG1 . VAL A 1 386 ? 158.742 147.608 188.354 1.00 74.59  ? 386 VAL A CG1 1 
ATOM   2590 C  CG2 . VAL A 1 386 ? 158.557 147.586 190.841 1.00 74.59  ? 386 VAL A CG2 1 
ATOM   2591 N  N   . THR A 1 387 ? 155.728 145.835 191.543 1.00 76.20  ? 387 THR A N   1 
ATOM   2592 C  CA  . THR A 1 387 ? 155.333 145.005 192.675 1.00 76.20  ? 387 THR A CA  1 
ATOM   2593 C  C   . THR A 1 387 ? 154.483 143.823 192.230 1.00 76.20  ? 387 THR A C   1 
ATOM   2594 O  O   . THR A 1 387 ? 154.512 142.767 192.870 1.00 76.20  ? 387 THR A O   1 
ATOM   2595 C  CB  . THR A 1 387 ? 154.577 145.832 193.713 1.00 76.20  ? 387 THR A CB  1 
ATOM   2596 O  OG1 . THR A 1 387 ? 153.595 146.641 193.058 1.00 76.20  ? 387 THR A OG1 1 
ATOM   2597 C  CG2 . THR A 1 387 ? 155.536 146.727 194.474 1.00 76.20  ? 387 THR A CG2 1 
ATOM   2598 N  N   . MET A 1 388 ? 153.728 143.976 191.144 1.00 81.73  ? 388 MET A N   1 
ATOM   2599 C  CA  . MET A 1 388 ? 152.875 142.906 190.650 1.00 81.73  ? 388 MET A CA  1 
ATOM   2600 C  C   . MET A 1 388 ? 153.628 141.860 189.839 1.00 81.73  ? 388 MET A C   1 
ATOM   2601 O  O   . MET A 1 388 ? 153.077 140.782 189.591 1.00 81.73  ? 388 MET A O   1 
ATOM   2602 C  CB  . MET A 1 388 ? 151.739 143.485 189.802 1.00 81.73  ? 388 MET A CB  1 
ATOM   2603 C  CG  . MET A 1 388 ? 150.776 144.356 190.582 1.00 81.73  ? 388 MET A CG  1 
ATOM   2604 S  SD  . MET A 1 388 ? 149.894 143.428 191.847 1.00 81.73  ? 388 MET A SD  1 
ATOM   2605 C  CE  . MET A 1 388 ? 149.059 144.753 192.711 1.00 81.73  ? 388 MET A CE  1 
ATOM   2606 N  N   . MET A 1 389 ? 154.857 142.146 189.416 1.00 83.05  ? 389 MET A N   1 
ATOM   2607 C  CA  . MET A 1 389 ? 155.659 141.144 188.736 1.00 83.05  ? 389 MET A CA  1 
ATOM   2608 C  C   . MET A 1 389 ? 156.076 140.042 189.707 1.00 83.05  ? 389 MET A C   1 
ATOM   2609 O  O   . MET A 1 389 ? 156.463 140.321 190.845 1.00 83.05  ? 389 MET A O   1 
ATOM   2610 C  CB  . MET A 1 389 ? 156.910 141.769 188.128 1.00 83.05  ? 389 MET A CB  1 
ATOM   2611 C  CG  . MET A 1 389 ? 156.697 143.101 187.454 1.00 83.05  ? 389 MET A CG  1 
ATOM   2612 S  SD  . MET A 1 389 ? 155.756 142.936 185.936 1.00 83.05  ? 389 MET A SD  1 
ATOM   2613 C  CE  . MET A 1 389 ? 157.057 143.100 184.719 1.00 83.05  ? 389 MET A CE  1 
ATOM   2614 N  N   . PRO A 1 390 ? 155.986 138.781 189.290 1.00 85.83  ? 390 PRO A N   1 
ATOM   2615 C  CA  . PRO A 1 390 ? 156.673 137.718 190.030 1.00 85.83  ? 390 PRO A CA  1 
ATOM   2616 C  C   . PRO A 1 390 ? 158.176 137.948 189.993 1.00 85.83  ? 390 PRO A C   1 
ATOM   2617 O  O   . PRO A 1 390 ? 158.723 138.392 188.980 1.00 85.83  ? 390 PRO A O   1 
ATOM   2618 C  CB  . PRO A 1 390 ? 156.269 136.442 189.283 1.00 85.83  ? 390 PRO A CB  1 
ATOM   2619 C  CG  . PRO A 1 390 ? 155.034 136.814 188.524 1.00 85.83  ? 390 PRO A CG  1 
ATOM   2620 C  CD  . PRO A 1 390 ? 155.197 138.254 188.166 1.00 85.83  ? 390 PRO A CD  1 
ATOM   2621 N  N   . LEU A 1 391 ? 158.836 137.627 191.108 1.00 86.09  ? 391 LEU A N   1 
ATOM   2622 C  CA  . LEU A 1 391 ? 160.215 138.032 191.390 1.00 86.09  ? 391 LEU A CA  1 
ATOM   2623 C  C   . LEU A 1 391 ? 160.372 139.544 191.208 1.00 86.09  ? 391 LEU A C   1 
ATOM   2624 O  O   . LEU A 1 391 ? 161.091 140.032 190.334 1.00 86.09  ? 391 LEU A O   1 
ATOM   2625 C  CB  . LEU A 1 391 ? 161.221 137.252 190.538 1.00 86.09  ? 391 LEU A CB  1 
ATOM   2626 C  CG  . LEU A 1 391 ? 162.640 137.164 191.104 1.00 86.09  ? 391 LEU A CG  1 
ATOM   2627 C  CD1 . LEU A 1 391 ? 162.621 136.705 192.556 1.00 86.09  ? 391 LEU A CD1 1 
ATOM   2628 C  CD2 . LEU A 1 391 ? 163.502 136.240 190.257 1.00 86.09  ? 391 LEU A CD2 1 
ATOM   2629 N  N   . SER A 1 392 ? 159.648 140.273 192.057 1.00 83.40  ? 392 SER A N   1 
ATOM   2630 C  CA  . SER A 1 392 ? 159.584 141.730 191.953 1.00 83.40  ? 392 SER A CA  1 
ATOM   2631 C  C   . SER A 1 392 ? 160.914 142.478 192.104 1.00 83.40  ? 392 SER A C   1 
ATOM   2632 O  O   . SER A 1 392 ? 161.136 143.410 191.309 1.00 83.40  ? 392 SER A O   1 
ATOM   2633 C  CB  . SER A 1 392 ? 158.541 142.255 192.952 1.00 83.40  ? 392 SER A CB  1 
ATOM   2634 O  OG  . SER A 1 392 ? 158.616 141.598 194.203 1.00 83.40  ? 392 SER A OG  1 
ATOM   2635 N  N   . PRO A 1 393 ? 161.804 142.183 193.074 1.00 83.04  ? 393 PRO A N   1 
ATOM   2636 C  CA  . PRO A 1 393 ? 163.030 142.998 193.182 1.00 83.04  ? 393 PRO A CA  1 
ATOM   2637 C  C   . PRO A 1 393 ? 163.945 142.918 191.975 1.00 83.04  ? 393 PRO A C   1 
ATOM   2638 O  O   . PRO A 1 393 ? 164.657 143.890 191.700 1.00 83.04  ? 393 PRO A O   1 
ATOM   2639 C  CB  . PRO A 1 393 ? 163.714 142.438 194.437 1.00 83.04  ? 393 PRO A CB  1 
ATOM   2640 C  CG  . PRO A 1 393 ? 162.632 141.827 195.209 1.00 83.04  ? 393 PRO A CG  1 
ATOM   2641 C  CD  . PRO A 1 393 ? 161.767 141.201 194.175 1.00 83.04  ? 393 PRO A CD  1 
ATOM   2642 N  N   . LEU A 1 394 ? 163.943 141.798 191.246 1.00 86.23  ? 394 LEU A N   1 
ATOM   2643 C  CA  . LEU A 1 394 ? 164.751 141.693 190.033 1.00 86.23  ? 394 LEU A CA  1 
ATOM   2644 C  C   . LEU A 1 394 ? 164.294 142.693 188.978 1.00 86.23  ? 394 LEU A C   1 
ATOM   2645 O  O   . LEU A 1 394 ? 165.110 143.431 188.408 1.00 86.23  ? 394 LEU A O   1 
ATOM   2646 C  CB  . LEU A 1 394 ? 164.683 140.270 189.481 1.00 86.23  ? 394 LEU A CB  1 
ATOM   2647 C  CG  . LEU A 1 394 ? 165.201 140.088 188.054 1.00 86.23  ? 394 LEU A CG  1 
ATOM   2648 C  CD1 . LEU A 1 394 ? 166.706 140.311 187.989 1.00 86.23  ? 394 LEU A CD1 1 
ATOM   2649 C  CD2 . LEU A 1 394 ? 164.826 138.718 187.514 1.00 86.23  ? 394 LEU A CD2 1 
ATOM   2650 N  N   . TRP A 1 395 ? 162.986 142.739 188.715 1.00 86.56  ? 395 TRP A N   1 
ATOM   2651 C  CA  . TRP A 1 395 ? 162.465 143.693 187.745 1.00 86.56  ? 395 TRP A CA  1 
ATOM   2652 C  C   . TRP A 1 395 ? 162.625 145.120 188.243 1.00 86.56  ? 395 TRP A C   1 
ATOM   2653 O  O   . TRP A 1 395 ? 162.868 146.032 187.447 1.00 86.56  ? 395 TRP A O   1 
ATOM   2654 C  CB  . TRP A 1 395 ? 161.004 143.385 187.430 1.00 86.56  ? 395 TRP A CB  1 
ATOM   2655 C  CG  . TRP A 1 395 ? 160.827 142.052 186.785 1.00 86.56  ? 395 TRP A CG  1 
ATOM   2656 C  CD1 . TRP A 1 395 ? 160.224 140.956 187.323 1.00 86.56  ? 395 TRP A CD1 1 
ATOM   2657 C  CD2 . TRP A 1 395 ? 161.280 141.663 185.483 1.00 86.56  ? 395 TRP A CD2 1 
ATOM   2658 N  NE1 . TRP A 1 395 ? 160.261 139.910 186.433 1.00 86.56  ? 395 TRP A NE1 1 
ATOM   2659 C  CE2 . TRP A 1 395 ? 160.906 140.319 185.296 1.00 86.56  ? 395 TRP A CE2 1 
ATOM   2660 C  CE3 . TRP A 1 395 ? 161.960 142.323 184.455 1.00 86.56  ? 395 TRP A CE3 1 
ATOM   2661 C  CZ2 . TRP A 1 395 ? 161.189 139.622 184.125 1.00 86.56  ? 395 TRP A CZ2 1 
ATOM   2662 C  CZ3 . TRP A 1 395 ? 162.241 141.630 183.294 1.00 86.56  ? 395 TRP A CZ3 1 
ATOM   2663 C  CH2 . TRP A 1 395 ? 161.856 140.293 183.138 1.00 86.56  ? 395 TRP A CH2 1 
ATOM   2664 N  N   . ALA A 1 396 ? 162.539 145.323 189.560 1.00 84.60  ? 396 ALA A N   1 
ATOM   2665 C  CA  . ALA A 1 396 ? 162.720 146.663 190.110 1.00 84.60  ? 396 ALA A CA  1 
ATOM   2666 C  C   . ALA A 1 396 ? 164.150 147.159 189.917 1.00 84.60  ? 396 ALA A C   1 
ATOM   2667 O  O   . ALA A 1 396 ? 164.364 148.292 189.469 1.00 84.60  ? 396 ALA A O   1 
ATOM   2668 C  CB  . ALA A 1 396 ? 162.330 146.680 191.586 1.00 84.60  ? 396 ALA A CB  1 
ATOM   2669 N  N   . THR A 1 397 ? 165.147 146.321 190.228 1.00 85.55  ? 397 THR A N   1 
ATOM   2670 C  CA  . THR A 1 397 ? 166.528 146.768 190.071 1.00 85.55  ? 397 THR A CA  1 
ATOM   2671 C  C   . THR A 1 397 ? 166.919 146.882 188.603 1.00 85.55  ? 397 THR A C   1 
ATOM   2672 O  O   . THR A 1 397 ? 167.696 147.775 188.247 1.00 85.55  ? 397 THR A O   1 
ATOM   2673 C  CB  . THR A 1 397 ? 167.504 145.858 190.832 1.00 85.55  ? 397 THR A CB  1 
ATOM   2674 O  OG1 . THR A 1 397 ? 168.822 146.415 190.764 1.00 85.55  ? 397 THR A OG1 1 
ATOM   2675 C  CG2 . THR A 1 397 ? 167.539 144.441 190.285 1.00 85.55  ? 397 THR A CG2 1 
ATOM   2676 N  N   . LEU A 1 398 ? 166.359 146.037 187.731 1.00 87.98  ? 398 LEU A N   1 
ATOM   2677 C  CA  . LEU A 1 398 ? 166.633 146.183 186.307 1.00 87.98  ? 398 LEU A CA  1 
ATOM   2678 C  C   . LEU A 1 398 ? 166.008 147.461 185.758 1.00 87.98  ? 398 LEU A C   1 
ATOM   2679 O  O   . LEU A 1 398 ? 166.621 148.158 184.941 1.00 87.98  ? 398 LEU A O   1 
ATOM   2680 C  CB  . LEU A 1 398 ? 166.126 144.959 185.551 1.00 87.98  ? 398 LEU A CB  1 
ATOM   2681 C  CG  . LEU A 1 398 ? 167.079 143.766 185.508 1.00 87.98  ? 398 LEU A CG  1 
ATOM   2682 C  CD1 . LEU A 1 398 ? 166.410 142.573 184.849 1.00 87.98  ? 398 LEU A CD1 1 
ATOM   2683 C  CD2 . LEU A 1 398 ? 168.363 144.137 184.787 1.00 87.98  ? 398 LEU A CD2 1 
ATOM   2684 N  N   . PHE A 1 399 ? 164.801 147.796 186.219 1.00 83.58  ? 399 PHE A N   1 
ATOM   2685 C  CA  . PHE A 1 399 ? 164.162 149.046 185.826 1.00 83.58  ? 399 PHE A CA  1 
ATOM   2686 C  C   . PHE A 1 399 ? 164.940 150.267 186.306 1.00 83.58  ? 399 PHE A C   1 
ATOM   2687 O  O   . PHE A 1 399 ? 165.099 151.247 185.566 1.00 83.58  ? 399 PHE A O   1 
ATOM   2688 C  CB  . PHE A 1 399 ? 162.739 149.087 186.368 1.00 83.58  ? 399 PHE A CB  1 
ATOM   2689 C  CG  . PHE A 1 399 ? 162.143 150.438 186.304 1.00 83.58  ? 399 PHE A CG  1 
ATOM   2690 C  CD1 . PHE A 1 399 ? 161.914 151.053 185.090 1.00 83.58  ? 399 PHE A CD1 1 
ATOM   2691 C  CD2 . PHE A 1 399 ? 161.881 151.131 187.467 1.00 83.58  ? 399 PHE A CD2 1 
ATOM   2692 C  CE1 . PHE A 1 399 ? 161.401 152.318 185.044 1.00 83.58  ? 399 PHE A CE1 1 
ATOM   2693 C  CE2 . PHE A 1 399 ? 161.367 152.393 187.421 1.00 83.58  ? 399 PHE A CE2 1 
ATOM   2694 C  CZ  . PHE A 1 399 ? 161.135 152.986 186.214 1.00 83.58  ? 399 PHE A CZ  1 
ATOM   2695 N  N   . PHE A 1 400 ? 165.404 150.247 187.554 1.00 79.39  ? 400 PHE A N   1 
ATOM   2696 C  CA  . PHE A 1 400 ? 166.131 151.412 188.046 1.00 79.39  ? 400 PHE A CA  1 
ATOM   2697 C  C   . PHE A 1 400 ? 167.502 151.524 187.393 1.00 79.39  ? 400 PHE A C   1 
ATOM   2698 O  O   . PHE A 1 400 ? 167.986 152.639 187.168 1.00 79.39  ? 400 PHE A O   1 
ATOM   2699 C  CB  . PHE A 1 400 ? 166.224 151.372 189.569 1.00 79.39  ? 400 PHE A CB  1 
ATOM   2700 C  CG  . PHE A 1 400 ? 164.911 151.634 190.250 1.00 79.39  ? 400 PHE A CG  1 
ATOM   2701 C  CD1 . PHE A 1 400 ? 164.098 152.671 189.826 1.00 79.39  ? 400 PHE A CD1 1 
ATOM   2702 C  CD2 . PHE A 1 400 ? 164.471 150.828 191.283 1.00 79.39  ? 400 PHE A CD2 1 
ATOM   2703 C  CE1 . PHE A 1 400 ? 162.885 152.914 190.438 1.00 79.39  ? 400 PHE A CE1 1 
ATOM   2704 C  CE2 . PHE A 1 400 ? 163.251 151.059 191.890 1.00 79.39  ? 400 PHE A CE2 1 
ATOM   2705 C  CZ  . PHE A 1 400 ? 162.459 152.104 191.465 1.00 79.39  ? 400 PHE A CZ  1 
ATOM   2706 N  N   . MET A 1 401 ? 168.114 150.394 187.028 1.00 89.20  ? 401 MET A N   1 
ATOM   2707 C  CA  . MET A 1 401 ? 169.338 150.448 186.238 1.00 89.20  ? 401 MET A CA  1 
ATOM   2708 C  C   . MET A 1 401 ? 169.074 150.996 184.838 1.00 89.20  ? 401 MET A C   1 
ATOM   2709 O  O   . MET A 1 401 ? 169.916 151.719 184.290 1.00 89.20  ? 401 MET A O   1 
ATOM   2710 C  CB  . MET A 1 401 ? 169.971 149.059 186.175 1.00 89.20  ? 401 MET A CB  1 
ATOM   2711 C  CG  . MET A 1 401 ? 171.355 149.026 185.559 1.00 89.20  ? 401 MET A CG  1 
ATOM   2712 S  SD  . MET A 1 401 ? 172.073 147.374 185.607 1.00 89.20  ? 401 MET A SD  1 
ATOM   2713 C  CE  . MET A 1 401 ? 172.419 147.213 187.356 1.00 89.20  ? 401 MET A CE  1 
ATOM   2714 N  N   . MET A 1 402 ? 167.909 150.678 184.259 1.00 88.73  ? 402 MET A N   1 
ATOM   2715 C  CA  . MET A 1 402 ? 167.504 151.291 182.996 1.00 88.73  ? 402 MET A CA  1 
ATOM   2716 C  C   . MET A 1 402 ? 167.407 152.804 183.123 1.00 88.73  ? 402 MET A C   1 
ATOM   2717 O  O   . MET A 1 402 ? 167.885 153.544 182.253 1.00 88.73  ? 402 MET A O   1 
ATOM   2718 C  CB  . MET A 1 402 ? 166.154 150.742 182.541 1.00 88.73  ? 402 MET A CB  1 
ATOM   2719 C  CG  . MET A 1 402 ? 165.688 151.350 181.233 1.00 88.73  ? 402 MET A CG  1 
ATOM   2720 S  SD  . MET A 1 402 ? 163.956 151.061 180.862 1.00 88.73  ? 402 MET A SD  1 
ATOM   2721 C  CE  . MET A 1 402 ? 163.193 152.279 181.921 1.00 88.73  ? 402 MET A CE  1 
ATOM   2722 N  N   . LEU A 1 403 ? 166.759 153.276 184.194 1.00 85.57  ? 403 LEU A N   1 
ATOM   2723 C  CA  . LEU A 1 403 ? 166.613 154.716 184.400 1.00 85.57  ? 403 LEU A CA  1 
ATOM   2724 C  C   . LEU A 1 403 ? 167.966 155.387 184.579 1.00 85.57  ? 403 LEU A C   1 
ATOM   2725 O  O   . LEU A 1 403 ? 168.203 156.471 184.030 1.00 85.57  ? 403 LEU A O   1 
ATOM   2726 C  CB  . LEU A 1 403 ? 165.724 155.006 185.606 1.00 85.57  ? 403 LEU A CB  1 
ATOM   2727 C  CG  . LEU A 1 403 ? 164.215 155.081 185.385 1.00 85.57  ? 403 LEU A CG  1 
ATOM   2728 C  CD1 . LEU A 1 403 ? 163.542 155.522 186.668 1.00 85.57  ? 403 LEU A CD1 1 
ATOM   2729 C  CD2 . LEU A 1 403 ? 163.878 156.023 184.252 1.00 85.57  ? 403 LEU A CD2 1 
ATOM   2730 N  N   . ILE A 1 404 ? 168.871 154.745 185.326 1.00 86.69  ? 404 ILE A N   1 
ATOM   2731 C  CA  . ILE A 1 404 ? 170.224 155.273 185.493 1.00 86.69  ? 404 ILE A CA  1 
ATOM   2732 C  C   . ILE A 1 404 ? 170.938 155.369 184.152 1.00 86.69  ? 404 ILE A C   1 
ATOM   2733 O  O   . ILE A 1 404 ? 171.565 156.389 183.846 1.00 86.69  ? 404 ILE A O   1 
ATOM   2734 C  CB  . ILE A 1 404 ? 171.016 154.420 186.501 1.00 86.69  ? 404 ILE A CB  1 
ATOM   2735 C  CG1 . ILE A 1 404 ? 170.426 154.581 187.895 1.00 86.69  ? 404 ILE A CG1 1 
ATOM   2736 C  CG2 . ILE A 1 404 ? 172.482 154.815 186.519 1.00 86.69  ? 404 ILE A CG2 1 
ATOM   2737 C  CD1 . ILE A 1 404 ? 170.407 156.009 188.348 1.00 86.69  ? 404 ILE A CD1 1 
ATOM   2738 N  N   . PHE A 1 405 ? 170.826 154.331 183.318 1.00 91.35  ? 405 PHE A N   1 
ATOM   2739 C  CA  . PHE A 1 405 ? 171.519 154.337 182.031 1.00 91.35  ? 405 PHE A CA  1 
ATOM   2740 C  C   . PHE A 1 405 ? 170.976 155.420 181.103 1.00 91.35  ? 405 PHE A C   1 
ATOM   2741 O  O   . PHE A 1 405 ? 171.747 156.206 180.532 1.00 91.35  ? 405 PHE A O   1 
ATOM   2742 C  CB  . PHE A 1 405 ? 171.412 152.962 181.373 1.00 91.35  ? 405 PHE A CB  1 
ATOM   2743 C  CG  . PHE A 1 405 ? 172.310 151.926 181.986 1.00 91.35  ? 405 PHE A CG  1 
ATOM   2744 C  CD1 . PHE A 1 405 ? 173.386 152.301 182.776 1.00 91.35  ? 405 PHE A CD1 1 
ATOM   2745 C  CD2 . PHE A 1 405 ? 172.080 150.578 181.771 1.00 91.35  ? 405 PHE A CD2 1 
ATOM   2746 C  CE1 . PHE A 1 405 ? 174.213 151.351 183.342 1.00 91.35  ? 405 PHE A CE1 1 
ATOM   2747 C  CE2 . PHE A 1 405 ? 172.905 149.622 182.333 1.00 91.35  ? 405 PHE A CE2 1 
ATOM   2748 C  CZ  . PHE A 1 405 ? 173.972 150.010 183.120 1.00 91.35  ? 405 PHE A CZ  1 
ATOM   2749 N  N   . LEU A 1 406 ? 169.651 155.496 180.954 1.00 88.74  ? 406 LEU A N   1 
ATOM   2750 C  CA  . LEU A 1 406 ? 169.094 156.456 180.009 1.00 88.74  ? 406 LEU A CA  1 
ATOM   2751 C  C   . LEU A 1 406 ? 169.059 157.878 180.552 1.00 88.74  ? 406 LEU A C   1 
ATOM   2752 O  O   . LEU A 1 406 ? 168.807 158.806 179.778 1.00 88.74  ? 406 LEU A O   1 
ATOM   2753 C  CB  . LEU A 1 406 ? 167.692 156.032 179.549 1.00 88.74  ? 406 LEU A CB  1 
ATOM   2754 C  CG  . LEU A 1 406 ? 166.488 155.853 180.476 1.00 88.74  ? 406 LEU A CG  1 
ATOM   2755 C  CD1 . LEU A 1 406 ? 165.715 157.138 180.698 1.00 88.74  ? 406 LEU A CD1 1 
ATOM   2756 C  CD2 . LEU A 1 406 ? 165.572 154.796 179.894 1.00 88.74  ? 406 LEU A CD2 1 
ATOM   2757 N  N   . GLY A 1 407 ? 169.300 158.080 181.845 1.00 88.07  ? 407 GLY A N   1 
ATOM   2758 C  CA  . GLY A 1 407 ? 169.498 159.428 182.329 1.00 88.07  ? 407 GLY A CA  1 
ATOM   2759 C  C   . GLY A 1 407 ? 170.948 159.838 182.206 1.00 88.07  ? 407 GLY A C   1 
ATOM   2760 O  O   . GLY A 1 407 ? 171.254 160.990 181.877 1.00 88.07  ? 407 GLY A O   1 
ATOM   2761 N  N   . LEU A 1 408 ? 171.852 158.886 182.456 1.00 91.67  ? 408 LEU A N   1 
ATOM   2762 C  CA  . LEU A 1 408 ? 173.278 159.160 182.382 1.00 91.67  ? 408 LEU A CA  1 
ATOM   2763 C  C   . LEU A 1 408 ? 173.727 159.444 180.960 1.00 91.67  ? 408 LEU A C   1 
ATOM   2764 O  O   . LEU A 1 408 ? 174.618 160.272 180.761 1.00 91.67  ? 408 LEU A O   1 
ATOM   2765 C  CB  . LEU A 1 408 ? 174.066 157.986 182.962 1.00 91.67  ? 408 LEU A CB  1 
ATOM   2766 C  CG  . LEU A 1 408 ? 174.438 158.062 184.442 1.00 91.67  ? 408 LEU A CG  1 
ATOM   2767 C  CD1 . LEU A 1 408 ? 175.403 156.949 184.795 1.00 91.67  ? 408 LEU A CD1 1 
ATOM   2768 C  CD2 . LEU A 1 408 ? 175.050 159.413 184.767 1.00 91.67  ? 408 LEU A CD2 1 
ATOM   2769 N  N   . ASP A 1 409 ? 173.132 158.778 179.965 1.00 96.98  ? 409 ASP A N   1 
ATOM   2770 C  CA  . ASP A 1 409 ? 173.495 159.053 178.575 1.00 96.98  ? 409 ASP A CA  1 
ATOM   2771 C  C   . ASP A 1 409 ? 173.146 160.486 178.183 1.00 96.98  ? 409 ASP A C   1 
ATOM   2772 O  O   . ASP A 1 409 ? 173.963 161.200 177.582 1.00 96.98  ? 409 ASP A O   1 
ATOM   2773 C  CB  . ASP A 1 409 ? 172.800 158.058 177.647 1.00 96.98  ? 409 ASP A CB  1 
ATOM   2774 C  CG  . ASP A 1 409 ? 173.322 156.646 177.812 1.00 96.98  ? 409 ASP A CG  1 
ATOM   2775 O  OD1 . ASP A 1 409 ? 174.121 156.412 178.742 1.00 96.98  ? 409 ASP A OD1 1 
ATOM   2776 O  OD2 . ASP A 1 409 ? 172.929 155.769 177.014 1.00 96.98  ? 409 ASP A OD2 1 
ATOM   2777 N  N   . SER A 1 410 ? 171.939 160.932 178.540 1.00 96.87  ? 410 SER A N   1 
ATOM   2778 C  CA  . SER A 1 410 ? 171.521 162.290 178.212 1.00 96.87  ? 410 SER A CA  1 
ATOM   2779 C  C   . SER A 1 410 ? 172.316 163.323 179.000 1.00 96.87  ? 410 SER A C   1 
ATOM   2780 O  O   . SER A 1 410 ? 172.688 164.369 178.458 1.00 96.87  ? 410 SER A O   1 
ATOM   2781 C  CB  . SER A 1 410 ? 170.024 162.455 178.463 1.00 96.87  ? 410 SER A CB  1 
ATOM   2782 O  OG  . SER A 1 410 ? 169.268 161.618 177.607 1.00 96.87  ? 410 SER A OG  1 
ATOM   2783 N  N   . GLN A 1 411 ? 172.599 163.041 180.276 1.00 96.28  ? 411 GLN A N   1 
ATOM   2784 C  CA  . GLN A 1 411 ? 173.418 163.954 181.068 1.00 96.28  ? 411 GLN A CA  1 
ATOM   2785 C  C   . GLN A 1 411 ? 174.835 164.047 180.516 1.00 96.28  ? 411 GLN A C   1 
ATOM   2786 O  O   . GLN A 1 411 ? 175.420 165.135 180.468 1.00 96.28  ? 411 GLN A O   1 
ATOM   2787 C  CB  . GLN A 1 411 ? 173.438 163.507 182.530 1.00 96.28  ? 411 GLN A CB  1 
ATOM   2788 C  CG  . GLN A 1 411 ? 174.221 164.422 183.466 1.00 96.28  ? 411 GLN A CG  1 
ATOM   2789 C  CD  . GLN A 1 411 ? 173.528 165.746 183.754 1.00 96.28  ? 411 GLN A CD  1 
ATOM   2790 O  OE1 . GLN A 1 411 ? 172.401 165.988 183.321 1.00 96.28  ? 411 GLN A OE1 1 
ATOM   2791 N  NE2 . GLN A 1 411 ? 174.211 166.615 184.488 1.00 96.28  ? 411 GLN A NE2 1 
ATOM   2792 N  N   . PHE A 1 412 ? 175.390 162.913 180.078 1.00 107.34 ? 412 PHE A N   1 
ATOM   2793 C  CA  . PHE A 1 412 ? 176.724 162.884 179.490 1.00 107.34 ? 412 PHE A CA  1 
ATOM   2794 C  C   . PHE A 1 412 ? 176.787 163.707 178.213 1.00 107.34 ? 412 PHE A C   1 
ATOM   2795 O  O   . PHE A 1 412 ? 177.696 164.526 178.041 1.00 107.34 ? 412 PHE A O   1 
ATOM   2796 C  CB  . PHE A 1 412 ? 177.132 161.435 179.221 1.00 107.34 ? 412 PHE A CB  1 
ATOM   2797 C  CG  . PHE A 1 412 ? 178.378 161.294 178.397 1.00 107.34 ? 412 PHE A CG  1 
ATOM   2798 C  CD1 . PHE A 1 412 ? 179.622 161.563 178.939 1.00 107.34 ? 412 PHE A CD1 1 
ATOM   2799 C  CD2 . PHE A 1 412 ? 178.302 160.877 177.077 1.00 107.34 ? 412 PHE A CD2 1 
ATOM   2800 C  CE1 . PHE A 1 412 ? 180.768 161.428 178.175 1.00 107.34 ? 412 PHE A CE1 1 
ATOM   2801 C  CE2 . PHE A 1 412 ? 179.442 160.740 176.309 1.00 107.34 ? 412 PHE A CE2 1 
ATOM   2802 C  CZ  . PHE A 1 412 ? 180.676 161.016 176.860 1.00 107.34 ? 412 PHE A CZ  1 
ATOM   2803 N  N   . VAL A 1 413 ? 175.824 163.510 177.305 1.00 105.73 ? 413 VAL A N   1 
ATOM   2804 C  CA  . VAL A 1 413 ? 175.876 164.265 176.054 1.00 105.73 ? 413 VAL A CA  1 
ATOM   2805 C  C   . VAL A 1 413 ? 175.585 165.746 176.297 1.00 105.73 ? 413 VAL A C   1 
ATOM   2806 O  O   . VAL A 1 413 ? 176.163 166.610 175.625 1.00 105.73 ? 413 VAL A O   1 
ATOM   2807 C  CB  . VAL A 1 413 ? 174.947 163.651 174.985 1.00 105.73 ? 413 VAL A CB  1 
ATOM   2808 C  CG1 . VAL A 1 413 ? 175.342 162.208 174.712 1.00 105.73 ? 413 VAL A CG1 1 
ATOM   2809 C  CG2 . VAL A 1 413 ? 173.485 163.732 175.382 1.00 105.73 ? 413 VAL A CG2 1 
ATOM   2810 N  N   . CYS A 1 414 ? 174.755 166.070 177.297 1.00 106.02 ? 414 CYS A N   1 
ATOM   2811 C  CA  . CYS A 1 414 ? 174.483 167.468 177.617 1.00 106.02 ? 414 CYS A CA  1 
ATOM   2812 C  C   . CYS A 1 414 ? 175.723 168.166 178.164 1.00 106.02 ? 414 CYS A C   1 
ATOM   2813 O  O   . CYS A 1 414 ? 176.086 169.258 177.703 1.00 106.02 ? 414 CYS A O   1 
ATOM   2814 C  CB  . CYS A 1 414 ? 173.330 167.556 178.617 1.00 106.02 ? 414 CYS A CB  1 
ATOM   2815 S  SG  . CYS A 1 414 ? 171.685 167.461 177.877 1.00 106.02 ? 414 CYS A SG  1 
ATOM   2816 N  N   . VAL A 1 415 ? 176.396 167.547 179.138 1.00 106.52 ? 415 VAL A N   1 
ATOM   2817 C  CA  . VAL A 1 415 ? 177.573 168.184 179.719 1.00 106.52 ? 415 VAL A CA  1 
ATOM   2818 C  C   . VAL A 1 415 ? 178.727 168.197 178.721 1.00 106.52 ? 415 VAL A C   1 
ATOM   2819 O  O   . VAL A 1 415 ? 179.530 169.137 178.713 1.00 106.52 ? 415 VAL A O   1 
ATOM   2820 C  CB  . VAL A 1 415 ? 177.954 167.519 181.062 1.00 106.52 ? 415 VAL A CB  1 
ATOM   2821 C  CG1 . VAL A 1 415 ? 178.488 166.107 180.875 1.00 106.52 ? 415 VAL A CG1 1 
ATOM   2822 C  CG2 . VAL A 1 415 ? 178.951 168.380 181.829 1.00 106.52 ? 415 VAL A CG2 1 
ATOM   2823 N  N   . GLU A 1 416 ? 178.803 167.200 177.830 1.00 112.07 ? 416 GLU A N   1 
ATOM   2824 C  CA  . GLU A 1 416 ? 179.844 167.199 176.809 1.00 112.07 ? 416 GLU A CA  1 
ATOM   2825 C  C   . GLU A 1 416 ? 179.621 168.312 175.795 1.00 112.07 ? 416 GLU A C   1 
ATOM   2826 O  O   . GLU A 1 416 ? 180.573 168.999 175.404 1.00 112.07 ? 416 GLU A O   1 
ATOM   2827 C  CB  . GLU A 1 416 ? 179.900 165.837 176.118 1.00 112.07 ? 416 GLU A CB  1 
ATOM   2828 C  CG  . GLU A 1 416 ? 180.917 165.748 174.992 1.00 112.07 ? 416 GLU A CG  1 
ATOM   2829 C  CD  . GLU A 1 416 ? 180.678 164.559 174.084 1.00 112.07 ? 416 GLU A CD  1 
ATOM   2830 O  OE1 . GLU A 1 416 ? 180.172 163.528 174.574 1.00 112.07 ? 416 GLU A OE1 1 
ATOM   2831 O  OE2 . GLU A 1 416 ? 180.998 164.654 172.880 1.00 112.07 ? 416 GLU A OE2 1 
ATOM   2832 N  N   . SER A 1 417 ? 178.369 168.517 175.371 1.00 113.47 ? 417 SER A N   1 
ATOM   2833 C  CA  . SER A 1 417 ? 178.062 169.624 174.471 1.00 113.47 ? 417 SER A CA  1 
ATOM   2834 C  C   . SER A 1 417 ? 178.344 170.967 175.133 1.00 113.47 ? 417 SER A C   1 
ATOM   2835 O  O   . SER A 1 417 ? 178.901 171.873 174.499 1.00 113.47 ? 417 SER A O   1 
ATOM   2836 C  CB  . SER A 1 417 ? 176.604 169.541 174.020 1.00 113.47 ? 417 SER A CB  1 
ATOM   2837 O  OG  . SER A 1 417 ? 175.722 169.735 175.111 1.00 113.47 ? 417 SER A OG  1 
ATOM   2838 N  N   . LEU A 1 418 ? 177.991 171.102 176.416 1.00 110.83 ? 418 LEU A N   1 
ATOM   2839 C  CA  . LEU A 1 418 ? 178.244 172.350 177.129 1.00 110.83 ? 418 LEU A CA  1 
ATOM   2840 C  C   . LEU A 1 418 ? 179.738 172.638 177.247 1.00 110.83 ? 418 LEU A C   1 
ATOM   2841 O  O   . LEU A 1 418 ? 180.180 173.768 176.996 1.00 110.83 ? 418 LEU A O   1 
ATOM   2842 C  CB  . LEU A 1 418 ? 177.597 172.301 178.513 1.00 110.83 ? 418 LEU A CB  1 
ATOM   2843 C  CG  . LEU A 1 418 ? 177.903 173.462 179.460 1.00 110.83 ? 418 LEU A CG  1 
ATOM   2844 C  CD1 . LEU A 1 418 ? 177.384 174.771 178.891 1.00 110.83 ? 418 LEU A CD1 1 
ATOM   2845 C  CD2 . LEU A 1 418 ? 177.311 173.203 180.833 1.00 110.83 ? 418 LEU A CD2 1 
ATOM   2846 N  N   . VAL A 1 419 ? 180.536 171.626 177.604 1.00 116.49 ? 419 VAL A N   1 
ATOM   2847 C  CA  . VAL A 1 419 ? 181.963 171.865 177.792 1.00 116.49 ? 419 VAL A CA  1 
ATOM   2848 C  C   . VAL A 1 419 ? 182.656 172.102 176.451 1.00 116.49 ? 419 VAL A C   1 
ATOM   2849 O  O   . VAL A 1 419 ? 183.552 172.949 176.352 1.00 116.49 ? 419 VAL A O   1 
ATOM   2850 C  CB  . VAL A 1 419 ? 182.621 170.734 178.614 1.00 116.49 ? 419 VAL A CB  1 
ATOM   2851 C  CG1 . VAL A 1 419 ? 182.671 169.408 177.870 1.00 116.49 ? 419 VAL A CG1 1 
ATOM   2852 C  CG2 . VAL A 1 419 ? 184.017 171.148 179.042 1.00 116.49 ? 419 VAL A CG2 1 
ATOM   2853 N  N   . THR A 1 420 ? 182.228 171.409 175.386 1.00 119.91 ? 420 THR A N   1 
ATOM   2854 C  CA  . THR A 1 420 ? 182.870 171.647 174.099 1.00 119.91 ? 420 THR A CA  1 
ATOM   2855 C  C   . THR A 1 420 ? 182.467 173.002 173.527 1.00 119.91 ? 420 THR A C   1 
ATOM   2856 O  O   . THR A 1 420 ? 183.287 173.659 172.877 1.00 119.91 ? 420 THR A O   1 
ATOM   2857 C  CB  . THR A 1 420 ? 182.586 170.494 173.121 1.00 119.91 ? 420 THR A CB  1 
ATOM   2858 O  OG1 . THR A 1 420 ? 183.531 170.538 172.044 1.00 119.91 ? 420 THR A OG1 1 
ATOM   2859 C  CG2 . THR A 1 420 ? 181.174 170.536 172.544 1.00 119.91 ? 420 THR A CG2 1 
ATOM   2860 N  N   . ALA A 1 421 ? 181.260 173.485 173.841 1.00 122.68 ? 421 ALA A N   1 
ATOM   2861 C  CA  . ALA A 1 421 ? 180.876 174.821 173.405 1.00 122.68 ? 421 ALA A CA  1 
ATOM   2862 C  C   . ALA A 1 421 ? 181.633 175.895 174.177 1.00 122.68 ? 421 ALA A C   1 
ATOM   2863 O  O   . ALA A 1 421 ? 182.070 176.895 173.590 1.00 122.68 ? 421 ALA A O   1 
ATOM   2864 C  CB  . ALA A 1 421 ? 179.368 175.007 173.553 1.00 122.68 ? 421 ALA A CB  1 
ATOM   2865 N  N   . VAL A 1 422 ? 181.816 175.706 175.487 1.00 125.57 ? 422 VAL A N   1 
ATOM   2866 C  CA  . VAL A 1 422 ? 182.504 176.735 176.262 1.00 125.57 ? 422 VAL A CA  1 
ATOM   2867 C  C   . VAL A 1 422 ? 184.010 176.729 175.996 1.00 125.57 ? 422 VAL A C   1 
ATOM   2868 O  O   . VAL A 1 422 ? 184.656 177.776 176.134 1.00 125.57 ? 422 VAL A O   1 
ATOM   2869 C  CB  . VAL A 1 422 ? 182.183 176.602 177.766 1.00 125.57 ? 422 VAL A CB  1 
ATOM   2870 C  CG1 . VAL A 1 422 ? 182.831 175.378 178.379 1.00 125.57 ? 422 VAL A CG1 1 
ATOM   2871 C  CG2 . VAL A 1 422 ? 182.543 177.877 178.535 1.00 125.57 ? 422 VAL A CG2 1 
ATOM   2872 N  N   . VAL A 1 423 ? 184.596 175.598 175.584 1.00 129.91 ? 423 VAL A N   1 
ATOM   2873 C  CA  . VAL A 1 423 ? 185.999 175.632 175.173 1.00 129.91 ? 423 VAL A CA  1 
ATOM   2874 C  C   . VAL A 1 423 ? 186.175 176.002 173.704 1.00 129.91 ? 423 VAL A C   1 
ATOM   2875 O  O   . VAL A 1 423 ? 187.289 176.364 173.299 1.00 129.91 ? 423 VAL A O   1 
ATOM   2876 C  CB  . VAL A 1 423 ? 186.734 174.306 175.444 1.00 129.91 ? 423 VAL A CB  1 
ATOM   2877 C  CG1 . VAL A 1 423 ? 186.619 173.917 176.909 1.00 129.91 ? 423 VAL A CG1 1 
ATOM   2878 C  CG2 . VAL A 1 423 ? 186.236 173.201 174.525 1.00 129.91 ? 423 VAL A CG2 1 
ATOM   2879 N  N   . ASP A 1 424 ? 185.121 175.915 172.891 1.00 132.34 ? 424 ASP A N   1 
ATOM   2880 C  CA  . ASP A 1 424 ? 185.204 176.475 171.550 1.00 132.34 ? 424 ASP A CA  1 
ATOM   2881 C  C   . ASP A 1 424 ? 185.077 177.991 171.586 1.00 132.34 ? 424 ASP A C   1 
ATOM   2882 O  O   . ASP A 1 424 ? 185.724 178.694 170.801 1.00 132.34 ? 424 ASP A O   1 
ATOM   2883 C  CB  . ASP A 1 424 ? 184.129 175.862 170.657 1.00 132.34 ? 424 ASP A CB  1 
ATOM   2884 C  CG  . ASP A 1 424 ? 184.543 174.522 170.093 1.00 132.34 ? 424 ASP A CG  1 
ATOM   2885 O  OD1 . ASP A 1 424 ? 185.312 173.812 170.772 1.00 132.34 ? 424 ASP A OD1 1 
ATOM   2886 O  OD2 . ASP A 1 424 ? 184.100 174.177 168.979 1.00 132.34 ? 424 ASP A OD2 1 
ATOM   2887 N  N   . MET A 1 425 ? 184.251 178.514 172.494 1.00 132.86 ? 425 MET A N   1 
ATOM   2888 C  CA  . MET A 1 425 ? 184.097 179.959 172.587 1.00 132.86 ? 425 MET A CA  1 
ATOM   2889 C  C   . MET A 1 425 ? 185.297 180.594 173.282 1.00 132.86 ? 425 MET A C   1 
ATOM   2890 O  O   . MET A 1 425 ? 185.645 181.741 172.985 1.00 132.86 ? 425 MET A O   1 
ATOM   2891 C  CB  . MET A 1 425 ? 182.779 180.287 173.294 1.00 132.86 ? 425 MET A CB  1 
ATOM   2892 C  CG  . MET A 1 425 ? 182.318 181.733 173.176 1.00 132.86 ? 425 MET A CG  1 
ATOM   2893 S  SD  . MET A 1 425 ? 182.987 182.901 174.368 1.00 132.86 ? 425 MET A SD  1 
ATOM   2894 C  CE  . MET A 1 425 ? 181.895 182.603 175.757 1.00 132.86 ? 425 MET A CE  1 
ATOM   2895 N  N   . TYR A 1 426 ? 185.947 179.856 174.191 1.00 138.96 ? 426 TYR A N   1 
ATOM   2896 C  CA  . TYR A 1 426 ? 187.244 180.200 174.765 1.00 138.96 ? 426 TYR A CA  1 
ATOM   2897 C  C   . TYR A 1 426 ? 188.303 179.210 174.290 1.00 138.96 ? 426 TYR A C   1 
ATOM   2898 O  O   . TYR A 1 426 ? 188.642 178.268 175.019 1.00 138.96 ? 426 TYR A O   1 
ATOM   2899 C  CB  . TYR A 1 426 ? 187.200 180.199 176.295 1.00 138.96 ? 426 TYR A CB  1 
ATOM   2900 C  CG  . TYR A 1 426 ? 186.413 181.315 176.946 1.00 138.96 ? 426 TYR A CG  1 
ATOM   2901 C  CD1 . TYR A 1 426 ? 186.031 182.439 176.229 1.00 138.96 ? 426 TYR A CD1 1 
ATOM   2902 C  CD2 . TYR A 1 426 ? 186.089 181.257 178.296 1.00 138.96 ? 426 TYR A CD2 1 
ATOM   2903 C  CE1 . TYR A 1 426 ? 185.333 183.466 176.836 1.00 138.96 ? 426 TYR A CE1 1 
ATOM   2904 C  CE2 . TYR A 1 426 ? 185.386 182.278 178.907 1.00 138.96 ? 426 TYR A CE2 1 
ATOM   2905 C  CZ  . TYR A 1 426 ? 185.010 183.377 178.173 1.00 138.96 ? 426 TYR A CZ  1 
ATOM   2906 O  OH  . TYR A 1 426 ? 184.306 184.398 178.770 1.00 138.96 ? 426 TYR A OH  1 
ATOM   2907 N  N   . PRO A 1 427 ? 188.859 179.393 173.088 1.00 143.33 ? 427 PRO A N   1 
ATOM   2908 C  CA  . PRO A 1 427 ? 189.811 178.408 172.552 1.00 143.33 ? 427 PRO A CA  1 
ATOM   2909 C  C   . PRO A 1 427 ? 191.234 178.533 173.081 1.00 143.33 ? 427 PRO A C   1 
ATOM   2910 O  O   . PRO A 1 427 ? 191.923 177.521 173.247 1.00 143.33 ? 427 PRO A O   1 
ATOM   2911 C  CB  . PRO A 1 427 ? 189.763 178.676 171.043 1.00 143.33 ? 427 PRO A CB  1 
ATOM   2912 C  CG  . PRO A 1 427 ? 189.407 180.123 170.927 1.00 143.33 ? 427 PRO A CG  1 
ATOM   2913 C  CD  . PRO A 1 427 ? 188.612 180.502 172.150 1.00 143.33 ? 427 PRO A CD  1 
ATOM   2914 N  N   . LYS A 1 428 ? 191.689 179.755 173.349 1.00 149.72 ? 428 LYS A N   1 
ATOM   2915 C  CA  . LYS A 1 428 ? 193.103 179.993 173.615 1.00 149.72 ? 428 LYS A CA  1 
ATOM   2916 C  C   . LYS A 1 428 ? 193.502 179.753 175.065 1.00 149.72 ? 428 LYS A C   1 
ATOM   2917 O  O   . LYS A 1 428 ? 194.687 179.887 175.388 1.00 149.72 ? 428 LYS A O   1 
ATOM   2918 C  CB  . LYS A 1 428 ? 193.481 181.424 173.221 1.00 149.72 ? 428 LYS A CB  1 
ATOM   2919 C  CG  . LYS A 1 428 ? 192.755 182.503 174.010 1.00 149.72 ? 428 LYS A CG  1 
ATOM   2920 C  CD  . LYS A 1 428 ? 193.258 183.897 173.658 1.00 149.72 ? 428 LYS A CD  1 
ATOM   2921 C  CE  . LYS A 1 428 ? 193.251 184.135 172.157 1.00 149.72 ? 428 LYS A CE  1 
ATOM   2922 N  NZ  . LYS A 1 428 ? 193.538 185.556 171.816 1.00 149.72 ? 428 LYS A NZ  1 
ATOM   2923 N  N   . VAL A 1 429 ? 192.564 179.410 175.944 1.00 149.59 ? 429 VAL A N   1 
ATOM   2924 C  CA  . VAL A 1 429 ? 192.852 179.249 177.360 1.00 149.59 ? 429 VAL A CA  1 
ATOM   2925 C  C   . VAL A 1 429 ? 192.679 177.802 177.818 1.00 149.59 ? 429 VAL A C   1 
ATOM   2926 O  O   . VAL A 1 429 ? 193.489 177.300 178.600 1.00 149.59 ? 429 VAL A O   1 
ATOM   2927 C  CB  . VAL A 1 429 ? 191.995 180.223 178.209 1.00 149.59 ? 429 VAL A CB  1 
ATOM   2928 C  CG1 . VAL A 1 429 ? 190.505 180.072 177.919 1.00 149.59 ? 429 VAL A CG1 1 
ATOM   2929 C  CG2 . VAL A 1 429 ? 192.283 180.067 179.700 1.00 149.59 ? 429 VAL A CG2 1 
ATOM   2930 N  N   . PHE A 1 430 ? 191.668 177.098 177.309 1.00 148.08 ? 430 PHE A N   1 
ATOM   2931 C  CA  . PHE A 1 430 ? 191.349 175.753 177.768 1.00 148.08 ? 430 PHE A CA  1 
ATOM   2932 C  C   . PHE A 1 430 ? 191.861 174.666 176.833 1.00 148.08 ? 430 PHE A C   1 
ATOM   2933 O  O   . PHE A 1 430 ? 191.543 173.489 177.036 1.00 148.08 ? 430 PHE A O   1 
ATOM   2934 C  CB  . PHE A 1 430 ? 189.839 175.609 177.960 1.00 148.08 ? 430 PHE A CB  1 
ATOM   2935 C  CG  . PHE A 1 430 ? 189.249 176.630 178.888 1.00 148.08 ? 430 PHE A CG  1 
ATOM   2936 C  CD1 . PHE A 1 430 ? 189.831 176.880 180.121 1.00 148.08 ? 430 PHE A CD1 1 
ATOM   2937 C  CD2 . PHE A 1 430 ? 188.119 177.345 178.527 1.00 148.08 ? 430 PHE A CD2 1 
ATOM   2938 C  CE1 . PHE A 1 430 ? 189.294 177.822 180.980 1.00 148.08 ? 430 PHE A CE1 1 
ATOM   2939 C  CE2 . PHE A 1 430 ? 187.577 178.288 179.381 1.00 148.08 ? 430 PHE A CE2 1 
ATOM   2940 C  CZ  . PHE A 1 430 ? 188.166 178.527 180.609 1.00 148.08 ? 430 PHE A CZ  1 
ATOM   2941 N  N   . ARG A 1 431 ? 192.644 175.027 175.814 1.00 151.81 ? 431 ARG A N   1 
ATOM   2942 C  CA  . ARG A 1 431 ? 193.186 174.051 174.876 1.00 151.81 ? 431 ARG A CA  1 
ATOM   2943 C  C   . ARG A 1 431 ? 194.704 174.140 174.776 1.00 151.81 ? 431 ARG A C   1 
ATOM   2944 O  O   . ARG A 1 431 ? 195.281 173.688 173.782 1.00 151.81 ? 431 ARG A O   1 
ATOM   2945 C  CB  . ARG A 1 431 ? 192.556 174.223 173.491 1.00 151.81 ? 431 ARG A CB  1 
ATOM   2946 N  N   . ARG A 1 432 ? 195.364 174.713 175.782 1.00 152.69 ? 432 ARG A N   1 
ATOM   2947 C  CA  . ARG A 1 432 ? 196.810 174.899 175.746 1.00 152.69 ? 432 ARG A CA  1 
ATOM   2948 C  C   . ARG A 1 432 ? 197.534 174.485 177.018 1.00 152.69 ? 432 ARG A C   1 
ATOM   2949 O  O   . ARG A 1 432 ? 198.757 174.304 176.968 1.00 152.69 ? 432 ARG A O   1 
ATOM   2950 C  CB  . ARG A 1 432 ? 197.152 176.366 175.444 1.00 152.69 ? 432 ARG A CB  1 
ATOM   2951 C  CG  . ARG A 1 432 ? 196.743 177.337 176.540 1.00 152.69 ? 432 ARG A CG  1 
ATOM   2952 C  CD  . ARG A 1 432 ? 197.591 178.597 176.508 1.00 152.69 ? 432 ARG A CD  1 
ATOM   2953 N  NE  . ARG A 1 432 ? 197.168 179.565 177.513 1.00 152.69 ? 432 ARG A NE  1 
ATOM   2954 C  CZ  . ARG A 1 432 ? 197.567 179.557 178.777 1.00 152.69 ? 432 ARG A CZ  1 
ATOM   2955 N  NH1 . ARG A 1 432 ? 198.408 178.642 179.231 1.00 152.69 ? 432 ARG A NH1 1 
ATOM   2956 N  NH2 . ARG A 1 432 ? 197.112 180.492 179.607 1.00 152.69 ? 432 ARG A NH2 1 
ATOM   2957 N  N   . GLY A 1 433 ? 196.843 174.326 178.144 1.00 152.75 ? 433 GLY A N   1 
ATOM   2958 C  CA  . GLY A 1 433 ? 197.518 174.021 179.390 1.00 152.75 ? 433 GLY A CA  1 
ATOM   2959 C  C   . GLY A 1 433 ? 197.016 172.779 180.097 1.00 152.75 ? 433 GLY A C   1 
ATOM   2960 O  O   . GLY A 1 433 ? 197.291 172.594 181.288 1.00 152.75 ? 433 GLY A O   1 
ATOM   2961 N  N   . TYR A 1 434 ? 196.287 171.928 179.366 1.00 151.39 ? 434 TYR A N   1 
ATOM   2962 C  CA  . TYR A 1 434 ? 195.712 170.677 179.874 1.00 151.39 ? 434 TYR A CA  1 
ATOM   2963 C  C   . TYR A 1 434 ? 194.813 170.934 181.087 1.00 151.39 ? 434 TYR A C   1 
ATOM   2964 O  O   . TYR A 1 434 ? 195.078 170.491 182.207 1.00 151.39 ? 434 TYR A O   1 
ATOM   2965 C  CB  . TYR A 1 434 ? 196.807 169.651 180.196 1.00 151.39 ? 434 TYR A CB  1 
ATOM   2966 C  CG  . TYR A 1 434 ? 196.277 168.263 180.482 1.00 151.39 ? 434 TYR A CG  1 
ATOM   2967 C  CD1 . TYR A 1 434 ? 195.513 167.583 179.542 1.00 151.39 ? 434 TYR A CD1 1 
ATOM   2968 C  CD2 . TYR A 1 434 ? 196.529 167.641 181.699 1.00 151.39 ? 434 TYR A CD2 1 
ATOM   2969 C  CE1 . TYR A 1 434 ? 195.024 166.316 179.801 1.00 151.39 ? 434 TYR A CE1 1 
ATOM   2970 C  CE2 . TYR A 1 434 ? 196.042 166.375 181.969 1.00 151.39 ? 434 TYR A CE2 1 
ATOM   2971 C  CZ  . TYR A 1 434 ? 195.290 165.717 181.016 1.00 151.39 ? 434 TYR A CZ  1 
ATOM   2972 O  OH  . TYR A 1 434 ? 194.804 164.457 181.278 1.00 151.39 ? 434 TYR A OH  1 
ATOM   2973 N  N   . ARG A 1 435 ? 193.737 171.684 180.843 1.00 149.17 ? 435 ARG A N   1 
ATOM   2974 C  CA  . ARG A 1 435 ? 192.799 172.042 181.899 1.00 149.17 ? 435 ARG A CA  1 
ATOM   2975 C  C   . ARG A 1 435 ? 191.347 171.808 181.502 1.00 149.17 ? 435 ARG A C   1 
ATOM   2976 O  O   . ARG A 1 435 ? 190.447 172.320 182.177 1.00 149.17 ? 435 ARG A O   1 
ATOM   2977 C  CB  . ARG A 1 435 ? 192.997 173.503 182.318 1.00 149.17 ? 435 ARG A CB  1 
ATOM   2978 C  CG  . ARG A 1 435 ? 192.938 174.494 181.170 1.00 149.17 ? 435 ARG A CG  1 
ATOM   2979 C  CD  . ARG A 1 435 ? 193.774 175.728 181.469 1.00 149.17 ? 435 ARG A CD  1 
ATOM   2980 N  NE  . ARG A 1 435 ? 195.190 175.411 181.612 1.00 149.17 ? 435 ARG A NE  1 
ATOM   2981 C  CZ  . ARG A 1 435 ? 195.986 175.936 182.533 1.00 149.17 ? 435 ARG A CZ  1 
ATOM   2982 N  NH1 . ARG A 1 435 ? 195.536 176.813 183.416 1.00 149.17 ? 435 ARG A NH1 1 
ATOM   2983 N  NH2 . ARG A 1 435 ? 197.265 175.574 182.569 1.00 149.17 ? 435 ARG A NH2 1 
ATOM   2984 N  N   . ARG A 1 436 ? 191.093 171.055 180.428 1.00 140.83 ? 436 ARG A N   1 
ATOM   2985 C  CA  . ARG A 1 436 ? 189.718 170.727 180.062 1.00 140.83 ? 436 ARG A CA  1 
ATOM   2986 C  C   . ARG A 1 436 ? 189.079 169.804 181.093 1.00 140.83 ? 436 ARG A C   1 
ATOM   2987 O  O   . ARG A 1 436 ? 187.928 170.014 181.495 1.00 140.83 ? 436 ARG A O   1 
ATOM   2988 C  CB  . ARG A 1 436 ? 189.685 170.097 178.670 1.00 140.83 ? 436 ARG A CB  1 
ATOM   2989 C  CG  . ARG A 1 436 ? 188.317 170.114 178.008 1.00 140.83 ? 436 ARG A CG  1 
ATOM   2990 C  CD  . ARG A 1 436 ? 188.312 169.274 176.741 1.00 140.83 ? 436 ARG A CD  1 
ATOM   2991 N  NE  . ARG A 1 436 ? 188.211 167.848 177.026 1.00 140.83 ? 436 ARG A NE  1 
ATOM   2992 C  CZ  . ARG A 1 436 ? 187.092 167.143 176.932 1.00 140.83 ? 436 ARG A CZ  1 
ATOM   2993 N  NH1 . ARG A 1 436 ? 185.953 167.701 176.557 1.00 140.83 ? 436 ARG A NH1 1 
ATOM   2994 N  NH2 . ARG A 1 436 ? 187.118 165.844 177.218 1.00 140.83 ? 436 ARG A NH2 1 
ATOM   2995 N  N   . GLU A 1 437 ? 189.817 168.787 181.547 1.00 139.75 ? 437 GLU A N   1 
ATOM   2996 C  CA  . GLU A 1 437 ? 189.313 167.914 182.603 1.00 139.75 ? 437 GLU A CA  1 
ATOM   2997 C  C   . GLU A 1 437 ? 189.175 168.656 183.925 1.00 139.75 ? 437 GLU A C   1 
ATOM   2998 O  O   . GLU A 1 437 ? 188.261 168.364 184.706 1.00 139.75 ? 437 GLU A O   1 
ATOM   2999 C  CB  . GLU A 1 437 ? 190.229 166.703 182.763 1.00 139.75 ? 437 GLU A CB  1 
ATOM   3000 C  CG  . GLU A 1 437 ? 190.342 165.851 181.512 1.00 139.75 ? 437 GLU A CG  1 
ATOM   3001 C  CD  . GLU A 1 437 ? 191.549 166.209 180.668 1.00 139.75 ? 437 GLU A CD  1 
ATOM   3002 O  OE1 . GLU A 1 437 ? 192.119 167.302 180.874 1.00 139.75 ? 437 GLU A OE1 1 
ATOM   3003 O  OE2 . GLU A 1 437 ? 191.927 165.397 179.797 1.00 139.75 ? 437 GLU A OE2 1 
ATOM   3004 N  N   . LEU A 1 438 ? 190.061 169.621 184.185 1.00 135.34 ? 438 LEU A N   1 
ATOM   3005 C  CA  . LEU A 1 438 ? 189.914 170.472 185.362 1.00 135.34 ? 438 LEU A CA  1 
ATOM   3006 C  C   . LEU A 1 438 ? 188.646 171.312 185.276 1.00 135.34 ? 438 LEU A C   1 
ATOM   3007 O  O   . LEU A 1 438 ? 187.948 171.494 186.280 1.00 135.34 ? 438 LEU A O   1 
ATOM   3008 C  CB  . LEU A 1 438 ? 191.141 171.371 185.526 1.00 135.34 ? 438 LEU A CB  1 
ATOM   3009 C  CG  . LEU A 1 438 ? 192.363 170.862 186.304 1.00 135.34 ? 438 LEU A CG  1 
ATOM   3010 C  CD1 . LEU A 1 438 ? 191.994 170.583 187.755 1.00 135.34 ? 438 LEU A CD1 1 
ATOM   3011 C  CD2 . LEU A 1 438 ? 193.020 169.641 185.662 1.00 135.34 ? 438 LEU A CD2 1 
ATOM   3012 N  N   . LEU A 1 439 ? 188.332 171.826 184.082 1.00 130.28 ? 439 LEU A N   1 
ATOM   3013 C  CA  . LEU A 1 439 ? 187.095 172.578 183.891 1.00 130.28 ? 439 LEU A CA  1 
ATOM   3014 C  C   . LEU A 1 439 ? 185.877 171.686 184.086 1.00 130.28 ? 439 LEU A C   1 
ATOM   3015 O  O   . LEU A 1 439 ? 184.875 172.119 184.665 1.00 130.28 ? 439 LEU A O   1 
ATOM   3016 C  CB  . LEU A 1 439 ? 187.082 173.220 182.501 1.00 130.28 ? 439 LEU A CB  1 
ATOM   3017 C  CG  . LEU A 1 439 ? 186.051 174.308 182.171 1.00 130.28 ? 439 LEU A CG  1 
ATOM   3018 C  CD1 . LEU A 1 439 ? 186.653 175.279 181.180 1.00 130.28 ? 439 LEU A CD1 1 
ATOM   3019 C  CD2 . LEU A 1 439 ? 184.756 173.748 181.599 1.00 130.28 ? 439 LEU A CD2 1 
ATOM   3020 N  N   . ILE A 1 440 ? 185.945 170.444 183.601 1.00 125.89 ? 440 ILE A N   1 
ATOM   3021 C  CA  . ILE A 1 440 ? 184.837 169.507 183.779 1.00 125.89 ? 440 ILE A CA  1 
ATOM   3022 C  C   . ILE A 1 440 ? 184.633 169.190 185.257 1.00 125.89 ? 440 ILE A C   1 
ATOM   3023 O  O   . ILE A 1 440 ? 183.497 169.157 185.748 1.00 125.89 ? 440 ILE A O   1 
ATOM   3024 C  CB  . ILE A 1 440 ? 185.074 168.235 182.942 1.00 125.89 ? 440 ILE A CB  1 
ATOM   3025 C  CG1 . ILE A 1 440 ? 185.039 168.579 181.455 1.00 125.89 ? 440 ILE A CG1 1 
ATOM   3026 C  CG2 . ILE A 1 440 ? 184.030 167.174 183.247 1.00 125.89 ? 440 ILE A CG2 1 
ATOM   3027 C  CD1 . ILE A 1 440 ? 185.563 167.496 180.553 1.00 125.89 ? 440 ILE A CD1 1 
ATOM   3028 N  N   . LEU A 1 441 ? 185.728 168.976 185.993 1.00 121.20 ? 441 LEU A N   1 
ATOM   3029 C  CA  . LEU A 1 441 ? 185.625 168.706 187.426 1.00 121.20 ? 441 LEU A CA  1 
ATOM   3030 C  C   . LEU A 1 441 ? 185.075 169.910 188.184 1.00 121.20 ? 441 LEU A C   1 
ATOM   3031 O  O   . LEU A 1 441 ? 184.243 169.756 189.088 1.00 121.20 ? 441 LEU A O   1 
ATOM   3032 C  CB  . LEU A 1 441 ? 186.992 168.290 187.976 1.00 121.20 ? 441 LEU A CB  1 
ATOM   3033 C  CG  . LEU A 1 441 ? 187.090 167.740 189.403 1.00 121.20 ? 441 LEU A CG  1 
ATOM   3034 C  CD1 . LEU A 1 441 ? 188.110 166.618 189.449 1.00 121.20 ? 441 LEU A CD1 1 
ATOM   3035 C  CD2 . LEU A 1 441 ? 187.476 168.823 190.404 1.00 121.20 ? 441 LEU A CD2 1 
ATOM   3036 N  N   . ALA A 1 442 ? 185.526 171.117 187.828 1.00 117.80 ? 442 ALA A N   1 
ATOM   3037 C  CA  . ALA A 1 442 ? 185.023 172.323 188.479 1.00 117.80 ? 442 ALA A CA  1 
ATOM   3038 C  C   . ALA A 1 442 ? 183.543 172.536 188.186 1.00 117.80 ? 442 ALA A C   1 
ATOM   3039 O  O   . ALA A 1 442 ? 182.778 172.912 189.082 1.00 117.80 ? 442 ALA A O   1 
ATOM   3040 C  CB  . ALA A 1 442 ? 185.838 173.537 188.038 1.00 117.80 ? 442 ALA A CB  1 
ATOM   3041 N  N   . LEU A 1 443 ? 183.122 172.291 186.941 1.00 113.90 ? 443 LEU A N   1 
ATOM   3042 C  CA  . LEU A 1 443 ? 181.713 172.418 186.586 1.00 113.90 ? 443 LEU A CA  1 
ATOM   3043 C  C   . LEU A 1 443 ? 180.867 171.384 187.315 1.00 113.90 ? 443 LEU A C   1 
ATOM   3044 O  O   . LEU A 1 443 ? 179.752 171.688 187.754 1.00 113.90 ? 443 LEU A O   1 
ATOM   3045 C  CB  . LEU A 1 443 ? 181.550 172.295 185.068 1.00 113.90 ? 443 LEU A CB  1 
ATOM   3046 C  CG  . LEU A 1 443 ? 180.210 172.632 184.407 1.00 113.90 ? 443 LEU A CG  1 
ATOM   3047 C  CD1 . LEU A 1 443 ? 180.463 173.265 183.053 1.00 113.90 ? 443 LEU A CD1 1 
ATOM   3048 C  CD2 . LEU A 1 443 ? 179.337 171.397 184.235 1.00 113.90 ? 443 LEU A CD2 1 
ATOM   3049 N  N   . SER A 1 444 ? 181.382 170.159 187.455 1.00 109.53 ? 444 SER A N   1 
ATOM   3050 C  CA  . SER A 1 444 ? 180.658 169.128 188.191 1.00 109.53 ? 444 SER A CA  1 
ATOM   3051 C  C   . SER A 1 444 ? 180.512 169.495 189.661 1.00 109.53 ? 444 SER A C   1 
ATOM   3052 O  O   . SER A 1 444 ? 179.439 169.316 190.245 1.00 109.53 ? 444 SER A O   1 
ATOM   3053 C  CB  . SER A 1 444 ? 181.367 167.782 188.042 1.00 109.53 ? 444 SER A CB  1 
ATOM   3054 O  OG  . SER A 1 444 ? 181.639 167.498 186.681 1.00 109.53 ? 444 SER A OG  1 
ATOM   3055 N  N   . VAL A 1 445 ? 181.573 170.033 190.268 1.00 106.35 ? 445 VAL A N   1 
ATOM   3056 C  CA  . VAL A 1 445 ? 181.508 170.445 191.670 1.00 106.35 ? 445 VAL A CA  1 
ATOM   3057 C  C   . VAL A 1 445 ? 180.523 171.599 191.848 1.00 106.35 ? 445 VAL A C   1 
ATOM   3058 O  O   . VAL A 1 445 ? 179.718 171.609 192.791 1.00 106.35 ? 445 VAL A O   1 
ATOM   3059 C  CB  . VAL A 1 445 ? 182.919 170.804 192.177 1.00 106.35 ? 445 VAL A CB  1 
ATOM   3060 C  CG1 . VAL A 1 445 ? 182.860 171.653 193.440 1.00 106.35 ? 445 VAL A CG1 1 
ATOM   3061 C  CG2 . VAL A 1 445 ? 183.724 169.540 192.424 1.00 106.35 ? 445 VAL A CG2 1 
ATOM   3062 N  N   . ILE A 1 446 ? 180.556 172.572 190.932 1.00 102.03 ? 446 ILE A N   1 
ATOM   3063 C  CA  . ILE A 1 446 ? 179.664 173.726 191.015 1.00 102.03 ? 446 ILE A CA  1 
ATOM   3064 C  C   . ILE A 1 446 ? 178.206 173.305 190.851 1.00 102.03 ? 446 ILE A C   1 
ATOM   3065 O  O   . ILE A 1 446 ? 177.335 173.730 191.622 1.00 102.03 ? 446 ILE A O   1 
ATOM   3066 C  CB  . ILE A 1 446 ? 180.080 174.782 189.973 1.00 102.03 ? 446 ILE A CB  1 
ATOM   3067 C  CG1 . ILE A 1 446 ? 181.345 175.511 190.430 1.00 102.03 ? 446 ILE A CG1 1 
ATOM   3068 C  CG2 . ILE A 1 446 ? 178.968 175.777 189.717 1.00 102.03 ? 446 ILE A CG2 1 
ATOM   3069 C  CD1 . ILE A 1 446 ? 181.950 176.405 189.370 1.00 102.03 ? 446 ILE A CD1 1 
ATOM   3070 N  N   . SER A 1 447 ? 177.918 172.445 189.871 1.00 97.30  ? 447 SER A N   1 
ATOM   3071 C  CA  . SER A 1 447 ? 176.548 171.987 189.671 1.00 97.30  ? 447 SER A CA  1 
ATOM   3072 C  C   . SER A 1 447 ? 176.099 171.007 190.747 1.00 97.30  ? 447 SER A C   1 
ATOM   3073 O  O   . SER A 1 447 ? 174.893 170.840 190.948 1.00 97.30  ? 447 SER A O   1 
ATOM   3074 C  CB  . SER A 1 447 ? 176.400 171.351 188.291 1.00 97.30  ? 447 SER A CB  1 
ATOM   3075 O  OG  . SER A 1 447 ? 176.441 172.332 187.269 1.00 97.30  ? 447 SER A OG  1 
ATOM   3076 N  N   . TYR A 1 448 ? 177.035 170.355 191.438 1.00 92.94  ? 448 TYR A N   1 
ATOM   3077 C  CA  . TYR A 1 448 ? 176.658 169.535 192.582 1.00 92.94  ? 448 TYR A CA  1 
ATOM   3078 C  C   . TYR A 1 448 ? 176.289 170.399 193.779 1.00 92.94  ? 448 TYR A C   1 
ATOM   3079 O  O   . TYR A 1 448 ? 175.319 170.107 194.485 1.00 92.94  ? 448 TYR A O   1 
ATOM   3080 C  CB  . TYR A 1 448 ? 177.797 168.583 192.940 1.00 92.94  ? 448 TYR A CB  1 
ATOM   3081 C  CG  . TYR A 1 448 ? 177.562 167.797 194.207 1.00 92.94  ? 448 TYR A CG  1 
ATOM   3082 C  CD1 . TYR A 1 448 ? 176.672 166.734 194.231 1.00 92.94  ? 448 TYR A CD1 1 
ATOM   3083 C  CD2 . TYR A 1 448 ? 178.233 168.116 195.380 1.00 92.94  ? 448 TYR A CD2 1 
ATOM   3084 C  CE1 . TYR A 1 448 ? 176.452 166.012 195.387 1.00 92.94  ? 448 TYR A CE1 1 
ATOM   3085 C  CE2 . TYR A 1 448 ? 178.020 167.400 196.541 1.00 92.94  ? 448 TYR A CE2 1 
ATOM   3086 C  CZ  . TYR A 1 448 ? 177.130 166.349 196.538 1.00 92.94  ? 448 TYR A CZ  1 
ATOM   3087 O  OH  . TYR A 1 448 ? 176.915 165.632 197.692 1.00 92.94  ? 448 TYR A OH  1 
ATOM   3088 N  N   . PHE A 1 449 ? 177.060 171.460 194.030 1.00 94.55  ? 449 PHE A N   1 
ATOM   3089 C  CA  . PHE A 1 449 ? 176.748 172.345 195.148 1.00 94.55  ? 449 PHE A CA  1 
ATOM   3090 C  C   . PHE A 1 449 ? 175.478 173.152 194.900 1.00 94.55  ? 449 PHE A C   1 
ATOM   3091 O  O   . PHE A 1 449 ? 174.689 173.362 195.827 1.00 94.55  ? 449 PHE A O   1 
ATOM   3092 C  CB  . PHE A 1 449 ? 177.927 173.272 195.441 1.00 94.55  ? 449 PHE A CB  1 
ATOM   3093 C  CG  . PHE A 1 449 ? 179.053 172.603 196.176 1.00 94.55  ? 449 PHE A CG  1 
ATOM   3094 C  CD1 . PHE A 1 449 ? 178.855 171.390 196.817 1.00 94.55  ? 449 PHE A CD1 1 
ATOM   3095 C  CD2 . PHE A 1 449 ? 180.306 173.191 196.236 1.00 94.55  ? 449 PHE A CD2 1 
ATOM   3096 C  CE1 . PHE A 1 449 ? 179.885 170.773 197.498 1.00 94.55  ? 449 PHE A CE1 1 
ATOM   3097 C  CE2 . PHE A 1 449 ? 181.342 172.578 196.916 1.00 94.55  ? 449 PHE A CE2 1 
ATOM   3098 C  CZ  . PHE A 1 449 ? 181.130 171.367 197.547 1.00 94.55  ? 449 PHE A CZ  1 
ATOM   3099 N  N   . LEU A 1 450 ? 175.260 173.618 193.668 1.00 89.86  ? 450 LEU A N   1 
ATOM   3100 C  CA  . LEU A 1 450 ? 173.999 174.293 193.376 1.00 89.86  ? 450 LEU A CA  1 
ATOM   3101 C  C   . LEU A 1 450 ? 172.850 173.304 193.248 1.00 89.86  ? 450 LEU A C   1 
ATOM   3102 O  O   . LEU A 1 450 ? 171.688 173.681 193.432 1.00 89.86  ? 450 LEU A O   1 
ATOM   3103 C  CB  . LEU A 1 450 ? 174.112 175.133 192.105 1.00 89.86  ? 450 LEU A CB  1 
ATOM   3104 C  CG  . LEU A 1 450 ? 175.121 176.281 192.108 1.00 89.86  ? 450 LEU A CG  1 
ATOM   3105 C  CD1 . LEU A 1 450 ? 175.518 176.632 190.688 1.00 89.86  ? 450 LEU A CD1 1 
ATOM   3106 C  CD2 . LEU A 1 450 ? 174.554 177.496 192.823 1.00 89.86  ? 450 LEU A CD2 1 
ATOM   3107 N  N   . GLY A 1 451 ? 173.148 172.043 192.930 1.00 83.78  ? 451 GLY A N   1 
ATOM   3108 C  CA  . GLY A 1 451 ? 172.102 171.046 192.806 1.00 83.78  ? 451 GLY A CA  1 
ATOM   3109 C  C   . GLY A 1 451 ? 171.586 170.518 194.126 1.00 83.78  ? 451 GLY A C   1 
ATOM   3110 O  O   . GLY A 1 451 ? 170.479 169.975 194.171 1.00 83.78  ? 451 GLY A O   1 
ATOM   3111 N  N   . LEU A 1 452 ? 172.356 170.675 195.204 1.00 80.46  ? 452 LEU A N   1 
ATOM   3112 C  CA  . LEU A 1 452 ? 171.985 170.112 196.498 1.00 80.46  ? 452 LEU A CA  1 
ATOM   3113 C  C   . LEU A 1 452 ? 170.836 170.848 197.169 1.00 80.46  ? 452 LEU A C   1 
ATOM   3114 O  O   . LEU A 1 452 ? 170.280 170.327 198.141 1.00 80.46  ? 452 LEU A O   1 
ATOM   3115 C  CB  . LEU A 1 452 ? 173.194 170.107 197.434 1.00 80.46  ? 452 LEU A CB  1 
ATOM   3116 C  CG  . LEU A 1 452 ? 173.960 168.791 197.554 1.00 80.46  ? 452 LEU A CG  1 
ATOM   3117 C  CD1 . LEU A 1 452 ? 175.120 168.937 198.522 1.00 80.46  ? 452 LEU A CD1 1 
ATOM   3118 C  CD2 . LEU A 1 452 ? 173.029 167.680 197.998 1.00 80.46  ? 452 LEU A CD2 1 
ATOM   3119 N  N   . VAL A 1 453 ? 170.467 172.037 196.686 1.00 76.03  ? 453 VAL A N   1 
ATOM   3120 C  CA  . VAL A 1 453 ? 169.400 172.800 197.321 1.00 76.03  ? 453 VAL A CA  1 
ATOM   3121 C  C   . VAL A 1 453 ? 168.036 172.161 197.080 1.00 76.03  ? 453 VAL A C   1 
ATOM   3122 O  O   . VAL A 1 453 ? 167.085 172.434 197.820 1.00 76.03  ? 453 VAL A O   1 
ATOM   3123 C  CB  . VAL A 1 453 ? 169.448 174.263 196.831 1.00 76.03  ? 453 VAL A CB  1 
ATOM   3124 C  CG1 . VAL A 1 453 ? 168.935 174.385 195.403 1.00 76.03  ? 453 VAL A CG1 1 
ATOM   3125 C  CG2 . VAL A 1 453 ? 168.699 175.194 197.780 1.00 76.03  ? 453 VAL A CG2 1 
ATOM   3126 N  N   . MET A 1 454 ? 167.919 171.290 196.075 1.00 73.59  ? 454 MET A N   1 
ATOM   3127 C  CA  . MET A 1 454 ? 166.651 170.637 195.786 1.00 73.59  ? 454 MET A CA  1 
ATOM   3128 C  C   . MET A 1 454 ? 166.476 169.327 196.541 1.00 73.59  ? 454 MET A C   1 
ATOM   3129 O  O   . MET A 1 454 ? 165.390 168.741 196.488 1.00 73.59  ? 454 MET A O   1 
ATOM   3130 C  CB  . MET A 1 454 ? 166.529 170.360 194.290 1.00 73.59  ? 454 MET A CB  1 
ATOM   3131 C  CG  . MET A 1 454 ? 166.927 171.511 193.407 1.00 73.59  ? 454 MET A CG  1 
ATOM   3132 S  SD  . MET A 1 454 ? 166.924 171.029 191.677 1.00 73.59  ? 454 MET A SD  1 
ATOM   3133 C  CE  . MET A 1 454 ? 167.385 172.577 190.922 1.00 73.59  ? 454 MET A CE  1 
ATOM   3134 N  N   . LEU A 1 455 ? 167.511 168.850 197.227 1.00 74.55  ? 455 LEU A N   1 
ATOM   3135 C  CA  . LEU A 1 455 ? 167.465 167.555 197.888 1.00 74.55  ? 455 LEU A CA  1 
ATOM   3136 C  C   . LEU A 1 455 ? 166.967 167.649 199.323 1.00 74.55  ? 455 LEU A C   1 
ATOM   3137 O  O   . LEU A 1 455 ? 166.895 166.625 200.009 1.00 74.55  ? 455 LEU A O   1 
ATOM   3138 C  CB  . LEU A 1 455 ? 168.845 166.889 197.880 1.00 74.55  ? 455 LEU A CB  1 
ATOM   3139 C  CG  . LEU A 1 455 ? 169.363 166.155 196.634 1.00 74.55  ? 455 LEU A CG  1 
ATOM   3140 C  CD1 . LEU A 1 455 ? 168.449 165.011 196.227 1.00 74.55  ? 455 LEU A CD1 1 
ATOM   3141 C  CD2 . LEU A 1 455 ? 169.652 167.074 195.465 1.00 74.55  ? 455 LEU A CD2 1 
ATOM   3142 N  N   . THR A 1 456 ? 166.625 168.845 199.791 1.00 76.12  ? 456 THR A N   1 
ATOM   3143 C  CA  . THR A 1 456 ? 166.221 169.045 201.176 1.00 76.12  ? 456 THR A CA  1 
ATOM   3144 C  C   . THR A 1 456 ? 164.781 168.572 201.373 1.00 76.12  ? 456 THR A C   1 
ATOM   3145 O  O   . THR A 1 456 ? 164.173 167.956 200.494 1.00 76.12  ? 456 THR A O   1 
ATOM   3146 C  CB  . THR A 1 456 ? 166.392 170.509 201.567 1.00 76.12  ? 456 THR A CB  1 
ATOM   3147 O  OG1 . THR A 1 456 ? 165.692 171.338 200.633 1.00 76.12  ? 456 THR A OG1 1 
ATOM   3148 C  CG2 . THR A 1 456 ? 167.859 170.890 201.557 1.00 76.12  ? 456 THR A CG2 1 
ATOM   3149 N  N   . GLU A 1 457 ? 164.224 168.849 202.554 1.00 80.19  ? 457 GLU A N   1 
ATOM   3150 C  CA  . GLU A 1 457 ? 162.848 168.454 202.840 1.00 80.19  ? 457 GLU A CA  1 
ATOM   3151 C  C   . GLU A 1 457 ? 161.857 169.226 201.977 1.00 80.19  ? 457 GLU A C   1 
ATOM   3152 O  O   . GLU A 1 457 ? 160.850 168.668 201.528 1.00 80.19  ? 457 GLU A O   1 
ATOM   3153 C  CB  . GLU A 1 457 ? 162.539 168.661 204.321 1.00 80.19  ? 457 GLU A CB  1 
ATOM   3154 C  CG  . GLU A 1 457 ? 163.055 167.556 205.222 1.00 80.19  ? 457 GLU A CG  1 
ATOM   3155 C  CD  . GLU A 1 457 ? 162.289 167.466 206.527 1.00 80.19  ? 457 GLU A CD  1 
ATOM   3156 O  OE1 . GLU A 1 457 ? 161.317 168.231 206.701 1.00 80.19  ? 457 GLU A OE1 1 
ATOM   3157 O  OE2 . GLU A 1 457 ? 162.658 166.630 207.378 1.00 80.19  ? 457 GLU A OE2 1 
ATOM   3158 N  N   . GLY A 1 458 ? 162.118 170.507 201.745 1.00 76.68  ? 458 GLY A N   1 
ATOM   3159 C  CA  . GLY A 1 458 ? 161.288 171.327 200.892 1.00 76.68  ? 458 GLY A CA  1 
ATOM   3160 C  C   . GLY A 1 458 ? 161.856 171.611 199.521 1.00 76.68  ? 458 GLY A C   1 
ATOM   3161 O  O   . GLY A 1 458 ? 161.307 172.456 198.806 1.00 76.68  ? 458 GLY A O   1 
ATOM   3162 N  N   . GLY A 1 459 ? 162.930 170.936 199.122 1.00 70.30  ? 459 GLY A N   1 
ATOM   3163 C  CA  . GLY A 1 459 ? 163.548 171.196 197.840 1.00 70.30  ? 459 GLY A CA  1 
ATOM   3164 C  C   . GLY A 1 459 ? 162.806 170.656 196.645 1.00 70.30  ? 459 GLY A C   1 
ATOM   3165 O  O   . GLY A 1 459 ? 163.157 170.973 195.503 1.00 70.30  ? 459 GLY A O   1 
ATOM   3166 N  N   . MET A 1 460 ? 161.778 169.841 196.885 1.00 67.77  ? 460 MET A N   1 
ATOM   3167 C  CA  . MET A 1 460 ? 160.957 169.332 195.795 1.00 67.77  ? 460 MET A CA  1 
ATOM   3168 C  C   . MET A 1 460 ? 160.211 170.458 195.095 1.00 67.77  ? 460 MET A C   1 
ATOM   3169 O  O   . MET A 1 460 ? 160.038 170.430 193.872 1.00 67.77  ? 460 MET A O   1 
ATOM   3170 C  CB  . MET A 1 460 ? 159.982 168.291 196.330 1.00 67.77  ? 460 MET A CB  1 
ATOM   3171 C  CG  . MET A 1 460 ? 159.180 167.599 195.265 1.00 67.77  ? 460 MET A CG  1 
ATOM   3172 S  SD  . MET A 1 460 ? 160.220 166.682 194.127 1.00 67.77  ? 460 MET A SD  1 
ATOM   3173 C  CE  . MET A 1 460 ? 159.095 166.502 192.761 1.00 67.77  ? 460 MET A CE  1 
ATOM   3174 N  N   . TYR A 1 461 ? 159.765 171.460 195.856 1.00 70.40  ? 461 TYR A N   1 
ATOM   3175 C  CA  . TYR A 1 461 ? 159.115 172.618 195.251 1.00 70.40  ? 461 TYR A CA  1 
ATOM   3176 C  C   . TYR A 1 461 ? 160.085 173.411 194.385 1.00 70.40  ? 461 TYR A C   1 
ATOM   3177 O  O   . TYR A 1 461 ? 159.702 173.919 193.326 1.00 70.40  ? 461 TYR A O   1 
ATOM   3178 C  CB  . TYR A 1 461 ? 158.513 173.509 196.333 1.00 70.40  ? 461 TYR A CB  1 
ATOM   3179 C  CG  . TYR A 1 461 ? 157.597 172.778 197.282 1.00 70.40  ? 461 TYR A CG  1 
ATOM   3180 C  CD1 . TYR A 1 461 ? 156.386 172.265 196.845 1.00 70.40  ? 461 TYR A CD1 1 
ATOM   3181 C  CD2 . TYR A 1 461 ? 157.936 172.612 198.616 1.00 70.40  ? 461 TYR A CD2 1 
ATOM   3182 C  CE1 . TYR A 1 461 ? 155.542 171.600 197.706 1.00 70.40  ? 461 TYR A CE1 1 
ATOM   3183 C  CE2 . TYR A 1 461 ? 157.098 171.949 199.484 1.00 70.40  ? 461 TYR A CE2 1 
ATOM   3184 C  CZ  . TYR A 1 461 ? 155.903 171.445 199.023 1.00 70.40  ? 461 TYR A CZ  1 
ATOM   3185 O  OH  . TYR A 1 461 ? 155.060 170.782 199.883 1.00 70.40  ? 461 TYR A OH  1 
ATOM   3186 N  N   . ILE A 1 462 ? 161.343 173.526 194.818 1.00 67.97  ? 462 ILE A N   1 
ATOM   3187 C  CA  . ILE A 1 462 ? 162.353 174.204 194.012 1.00 67.97  ? 462 ILE A CA  1 
ATOM   3188 C  C   . ILE A 1 462 ? 162.616 173.434 192.725 1.00 67.97  ? 462 ILE A C   1 
ATOM   3189 O  O   . ILE A 1 462 ? 162.758 174.029 191.647 1.00 67.97  ? 462 ILE A O   1 
ATOM   3190 C  CB  . ILE A 1 462 ? 163.642 174.401 194.828 1.00 67.97  ? 462 ILE A CB  1 
ATOM   3191 C  CG1 . ILE A 1 462 ? 163.319 175.040 196.179 1.00 67.97  ? 462 ILE A CG1 1 
ATOM   3192 C  CG2 . ILE A 1 462 ? 164.631 175.253 194.057 1.00 67.97  ? 462 ILE A CG2 1 
ATOM   3193 C  CD1 . ILE A 1 462 ? 164.540 175.398 196.999 1.00 67.97  ? 462 ILE A CD1 1 
ATOM   3194 N  N   . PHE A 1 463 ? 162.678 172.100 192.815 1.00 64.91  ? 463 PHE A N   1 
ATOM   3195 C  CA  . PHE A 1 463 ? 162.850 171.288 191.612 1.00 64.91  ? 463 PHE A CA  1 
ATOM   3196 C  C   . PHE A 1 463 ? 161.664 171.434 190.670 1.00 64.91  ? 463 PHE A C   1 
ATOM   3197 O  O   . PHE A 1 463 ? 161.841 171.497 189.451 1.00 64.91  ? 463 PHE A O   1 
ATOM   3198 C  CB  . PHE A 1 463 ? 163.044 169.818 191.973 1.00 64.91  ? 463 PHE A CB  1 
ATOM   3199 C  CG  . PHE A 1 463 ? 162.974 168.898 190.789 1.00 64.91  ? 463 PHE A CG  1 
ATOM   3200 C  CD1 . PHE A 1 463 ? 163.989 168.883 189.851 1.00 64.91  ? 463 PHE A CD1 1 
ATOM   3201 C  CD2 . PHE A 1 463 ? 161.887 168.064 190.603 1.00 64.91  ? 463 PHE A CD2 1 
ATOM   3202 C  CE1 . PHE A 1 463 ? 163.927 168.046 188.760 1.00 64.91  ? 463 PHE A CE1 1 
ATOM   3203 C  CE2 . PHE A 1 463 ? 161.821 167.227 189.510 1.00 64.91  ? 463 PHE A CE2 1 
ATOM   3204 C  CZ  . PHE A 1 463 ? 162.844 167.218 188.589 1.00 64.91  ? 463 PHE A CZ  1 
ATOM   3205 N  N   . GLN A 1 464 ? 160.448 171.479 191.217 1.00 66.30  ? 464 GLN A N   1 
ATOM   3206 C  CA  . GLN A 1 464 ? 159.259 171.660 190.390 1.00 66.30  ? 464 GLN A CA  1 
ATOM   3207 C  C   . GLN A 1 464 ? 159.264 173.016 189.700 1.00 66.30  ? 464 GLN A C   1 
ATOM   3208 O  O   . GLN A 1 464 ? 158.935 173.114 188.510 1.00 66.30  ? 464 GLN A O   1 
ATOM   3209 C  CB  . GLN A 1 464 ? 158.004 171.497 191.246 1.00 66.30  ? 464 GLN A CB  1 
ATOM   3210 C  CG  . GLN A 1 464 ? 156.715 172.012 190.630 1.00 66.30  ? 464 GLN A CG  1 
ATOM   3211 C  CD  . GLN A 1 464 ? 156.075 171.025 189.678 1.00 66.30  ? 464 GLN A CD  1 
ATOM   3212 O  OE1 . GLN A 1 464 ? 156.734 170.439 188.824 1.00 66.30  ? 464 GLN A OE1 1 
ATOM   3213 N  NE2 . GLN A 1 464 ? 154.777 170.816 189.843 1.00 66.30  ? 464 GLN A NE2 1 
ATOM   3214 N  N   . LEU A 1 465 ? 159.650 174.065 190.431 1.00 69.15  ? 465 LEU A N   1 
ATOM   3215 C  CA  . LEU A 1 465 ? 159.729 175.402 189.854 1.00 69.15  ? 465 LEU A CA  1 
ATOM   3216 C  C   . LEU A 1 465 ? 160.740 175.454 188.721 1.00 69.15  ? 465 LEU A C   1 
ATOM   3217 O  O   . LEU A 1 465 ? 160.453 175.989 187.644 1.00 69.15  ? 465 LEU A O   1 
ATOM   3218 C  CB  . LEU A 1 465 ? 160.091 176.418 190.934 1.00 69.15  ? 465 LEU A CB  1 
ATOM   3219 C  CG  . LEU A 1 465 ? 158.925 177.172 191.565 1.00 69.15  ? 465 LEU A CG  1 
ATOM   3220 C  CD1 . LEU A 1 465 ? 159.435 178.198 192.558 1.00 69.15  ? 465 LEU A CD1 1 
ATOM   3221 C  CD2 . LEU A 1 465 ? 158.093 177.833 190.484 1.00 69.15  ? 465 LEU A CD2 1 
ATOM   3222 N  N   . PHE A 1 466 ? 161.925 174.875 188.930 1.00 71.00  ? 466 PHE A N   1 
ATOM   3223 C  CA  . PHE A 1 466 ? 162.937 174.956 187.881 1.00 71.00  ? 466 PHE A CA  1 
ATOM   3224 C  C   . PHE A 1 466 ? 162.632 174.015 186.724 1.00 71.00  ? 466 PHE A C   1 
ATOM   3225 O  O   . PHE A 1 466 ? 163.023 174.297 185.588 1.00 71.00  ? 466 PHE A O   1 
ATOM   3226 C  CB  . PHE A 1 466 ? 164.333 174.694 188.444 1.00 71.00  ? 466 PHE A CB  1 
ATOM   3227 C  CG  . PHE A 1 466 ? 164.878 175.830 189.271 1.00 71.00  ? 466 PHE A CG  1 
ATOM   3228 C  CD1 . PHE A 1 466 ? 164.201 177.039 189.355 1.00 71.00  ? 466 PHE A CD1 1 
ATOM   3229 C  CD2 . PHE A 1 466 ? 166.087 175.704 189.928 1.00 71.00  ? 466 PHE A CD2 1 
ATOM   3230 C  CE1 . PHE A 1 466 ? 164.705 178.085 190.103 1.00 71.00  ? 466 PHE A CE1 1 
ATOM   3231 C  CE2 . PHE A 1 466 ? 166.599 176.746 190.678 1.00 71.00  ? 466 PHE A CE2 1 
ATOM   3232 C  CZ  . PHE A 1 466 ? 165.906 177.939 190.765 1.00 71.00  ? 466 PHE A CZ  1 
ATOM   3233 N  N   . ASP A 1 467 ? 161.917 172.917 186.978 1.00 68.25  ? 467 ASP A N   1 
ATOM   3234 C  CA  . ASP A 1 467 ? 161.487 172.050 185.888 1.00 68.25  ? 467 ASP A CA  1 
ATOM   3235 C  C   . ASP A 1 467 ? 160.440 172.733 185.025 1.00 68.25  ? 467 ASP A C   1 
ATOM   3236 O  O   . ASP A 1 467 ? 160.456 172.598 183.798 1.00 68.25  ? 467 ASP A O   1 
ATOM   3237 C  CB  . ASP A 1 467 ? 160.940 170.738 186.444 1.00 68.25  ? 467 ASP A CB  1 
ATOM   3238 C  CG  . ASP A 1 467 ? 160.385 169.837 185.363 1.00 68.25  ? 467 ASP A CG  1 
ATOM   3239 O  OD1 . ASP A 1 467 ? 160.992 169.769 184.275 1.00 68.25  ? 467 ASP A OD1 1 
ATOM   3240 O  OD2 . ASP A 1 467 ? 159.337 169.202 185.599 1.00 68.25  ? 467 ASP A OD2 1 
ATOM   3241 N  N   . SER A 1 468 ? 159.515 173.461 185.645 1.00 67.19  ? 468 SER A N   1 
ATOM   3242 C  CA  . SER A 1 468 ? 158.493 174.147 184.872 1.00 67.19  ? 468 SER A CA  1 
ATOM   3243 C  C   . SER A 1 468 ? 158.979 175.450 184.254 1.00 67.19  ? 468 SER A C   1 
ATOM   3244 O  O   . SER A 1 468 ? 158.355 175.924 183.300 1.00 67.19  ? 468 SER A O   1 
ATOM   3245 C  CB  . SER A 1 468 ? 157.275 174.437 185.745 1.00 67.19  ? 468 SER A CB  1 
ATOM   3246 O  OG  . SER A 1 468 ? 157.576 175.453 186.682 1.00 67.19  ? 468 SER A OG  1 
ATOM   3247 N  N   . TYR A 1 469 ? 160.066 176.042 184.757 1.00 70.31  ? 469 TYR A N   1 
ATOM   3248 C  CA  . TYR A 1 469 ? 160.453 177.367 184.300 1.00 70.31  ? 469 TYR A CA  1 
ATOM   3249 C  C   . TYR A 1 469 ? 161.864 177.485 183.740 1.00 70.31  ? 469 TYR A C   1 
ATOM   3250 O  O   . TYR A 1 469 ? 162.265 178.599 183.390 1.00 70.31  ? 469 TYR A O   1 
ATOM   3251 C  CB  . TYR A 1 469 ? 160.304 178.383 185.443 1.00 70.31  ? 469 TYR A CB  1 
ATOM   3252 C  CG  . TYR A 1 469 ? 158.889 178.862 185.662 1.00 70.31  ? 469 TYR A CG  1 
ATOM   3253 C  CD1 . TYR A 1 469 ? 157.953 178.816 184.639 1.00 70.31  ? 469 TYR A CD1 1 
ATOM   3254 C  CD2 . TYR A 1 469 ? 158.489 179.363 186.893 1.00 70.31  ? 469 TYR A CD2 1 
ATOM   3255 C  CE1 . TYR A 1 469 ? 156.655 179.252 184.836 1.00 70.31  ? 469 TYR A CE1 1 
ATOM   3256 C  CE2 . TYR A 1 469 ? 157.195 179.802 187.100 1.00 70.31  ? 469 TYR A CE2 1 
ATOM   3257 C  CZ  . TYR A 1 469 ? 156.283 179.744 186.068 1.00 70.31  ? 469 TYR A CZ  1 
ATOM   3258 O  OH  . TYR A 1 469 ? 154.994 180.179 186.268 1.00 70.31  ? 469 TYR A OH  1 
ATOM   3259 N  N   . ALA A 1 470 ? 162.634 176.400 183.638 1.00 69.75  ? 470 ALA A N   1 
ATOM   3260 C  CA  . ALA A 1 470 ? 163.994 176.514 183.129 1.00 69.75  ? 470 ALA A CA  1 
ATOM   3261 C  C   . ALA A 1 470 ? 164.172 175.865 181.764 1.00 69.75  ? 470 ALA A C   1 
ATOM   3262 O  O   . ALA A 1 470 ? 164.478 176.558 180.791 1.00 69.75  ? 470 ALA A O   1 
ATOM   3263 C  CB  . ALA A 1 470 ? 164.972 175.893 184.128 1.00 69.75  ? 470 ALA A CB  1 
ATOM   3264 N  N   . ALA A 1 471 ? 163.990 174.556 181.658 1.00 68.22  ? 471 ALA A N   1 
ATOM   3265 C  CA  . ALA A 1 471 ? 163.946 173.898 180.353 1.00 68.22  ? 471 ALA A CA  1 
ATOM   3266 C  C   . ALA A 1 471 ? 162.511 173.653 179.916 1.00 68.22  ? 471 ALA A C   1 
ATOM   3267 O  O   . ALA A 1 471 ? 162.160 172.557 179.483 1.00 68.22  ? 471 ALA A O   1 
ATOM   3268 C  CB  . ALA A 1 471 ? 164.738 172.599 180.388 1.00 68.22  ? 471 ALA A CB  1 
ATOM   3269 N  N   . SER A 1 472 ? 161.682 174.689 179.990 1.00 70.83  ? 472 SER A N   1 
ATOM   3270 C  CA  . SER A 1 472 ? 160.253 174.560 179.740 1.00 70.83  ? 472 SER A CA  1 
ATOM   3271 C  C   . SER A 1 472 ? 159.640 175.947 179.681 1.00 70.83  ? 472 SER A C   1 
ATOM   3272 O  O   . SER A 1 472 ? 160.242 176.934 180.112 1.00 70.83  ? 472 SER A O   1 
ATOM   3273 C  CB  . SER A 1 472 ? 159.552 173.730 180.821 1.00 70.83  ? 472 SER A CB  1 
ATOM   3274 O  OG  . SER A 1 472 ? 158.146 173.759 180.652 1.00 70.83  ? 472 SER A OG  1 
ATOM   3275 N  N   . GLY A 1 473 ? 158.426 175.997 179.150 1.00 74.65  ? 473 GLY A N   1 
ATOM   3276 C  CA  . GLY A 1 473 ? 157.650 177.223 179.154 1.00 74.65  ? 473 GLY A CA  1 
ATOM   3277 C  C   . GLY A 1 473 ? 158.237 178.311 178.278 1.00 74.65  ? 473 GLY A C   1 
ATOM   3278 O  O   . GLY A 1 473 ? 158.564 178.112 177.096 1.00 74.65  ? 473 GLY A O   1 
ATOM   3279 N  N   . MET A 1 474 ? 158.379 179.487 178.888 1.00 78.75  ? 474 MET A N   1 
ATOM   3280 C  CA  . MET A 1 474 ? 158.651 180.701 178.136 1.00 78.75  ? 474 MET A CA  1 
ATOM   3281 C  C   . MET A 1 474 ? 160.057 180.710 177.561 1.00 78.75  ? 474 MET A C   1 
ATOM   3282 O  O   . MET A 1 474 ? 160.284 181.327 176.518 1.00 78.75  ? 474 MET A O   1 
ATOM   3283 C  CB  . MET A 1 474 ? 158.417 181.913 179.032 1.00 78.75  ? 474 MET A CB  1 
ATOM   3284 C  CG  . MET A 1 474 ? 157.015 181.962 179.638 1.00 78.75  ? 474 MET A CG  1 
ATOM   3285 S  SD  . MET A 1 474 ? 155.671 182.004 178.431 1.00 78.75  ? 474 MET A SD  1 
ATOM   3286 C  CE  . MET A 1 474 ? 155.069 180.314 178.484 1.00 78.75  ? 474 MET A CE  1 
ATOM   3287 N  N   . CYS A 1 475 ? 160.997 180.009 178.200 1.00 78.45  ? 475 CYS A N   1 
ATOM   3288 C  CA  . CYS A 1 475 ? 162.361 179.950 177.687 1.00 78.45  ? 475 CYS A CA  1 
ATOM   3289 C  C   . CYS A 1 475 ? 162.406 179.256 176.332 1.00 78.45  ? 475 CYS A C   1 
ATOM   3290 O  O   . CYS A 1 475 ? 162.904 179.818 175.347 1.00 78.45  ? 475 CYS A O   1 
ATOM   3291 C  CB  . CYS A 1 475 ? 163.253 179.220 178.687 1.00 78.45  ? 475 CYS A CB  1 
ATOM   3292 S  SG  . CYS A 1 475 ? 163.078 179.809 180.377 1.00 78.45  ? 475 CYS A SG  1 
ATOM   3293 N  N   . LEU A 1 476 ? 161.846 178.046 176.258 1.00 74.82  ? 476 LEU A N   1 
ATOM   3294 C  CA  . LEU A 1 476 ? 161.842 177.302 175.004 1.00 74.82  ? 476 LEU A CA  1 
ATOM   3295 C  C   . LEU A 1 476 ? 160.957 177.973 173.965 1.00 74.82  ? 476 LEU A C   1 
ATOM   3296 O  O   . LEU A 1 476 ? 161.301 177.995 172.777 1.00 74.82  ? 476 LEU A O   1 
ATOM   3297 C  CB  . LEU A 1 476 ? 161.392 175.864 175.248 1.00 74.82  ? 476 LEU A CB  1 
ATOM   3298 C  CG  . LEU A 1 476 ? 162.398 174.980 175.983 1.00 74.82  ? 476 LEU A CG  1 
ATOM   3299 C  CD1 . LEU A 1 476 ? 161.873 173.563 176.103 1.00 74.82  ? 476 LEU A CD1 1 
ATOM   3300 C  CD2 . LEU A 1 476 ? 163.737 174.996 175.272 1.00 74.82  ? 476 LEU A CD2 1 
ATOM   3301 N  N   . LEU A 1 477 ? 159.824 178.542 174.395 1.00 73.41  ? 477 LEU A N   1 
ATOM   3302 C  CA  . LEU A 1 477 ? 158.952 179.236 173.450 1.00 73.41  ? 477 LEU A CA  1 
ATOM   3303 C  C   . LEU A 1 477 ? 159.645 180.446 172.831 1.00 73.41  ? 477 LEU A C   1 
ATOM   3304 O  O   . LEU A 1 477 ? 159.599 180.633 171.611 1.00 73.41  ? 477 LEU A O   1 
ATOM   3305 C  CB  . LEU A 1 477 ? 157.656 179.654 174.141 1.00 73.41  ? 477 LEU A CB  1 
ATOM   3306 C  CG  . LEU A 1 477 ? 156.603 178.564 174.358 1.00 73.41  ? 477 LEU A CG  1 
ATOM   3307 C  CD1 . LEU A 1 477 ? 155.248 179.186 174.638 1.00 73.41  ? 477 LEU A CD1 1 
ATOM   3308 C  CD2 . LEU A 1 477 ? 156.523 177.623 173.169 1.00 73.41  ? 477 LEU A CD2 1 
ATOM   3309 N  N   . PHE A 1 478 ? 160.325 181.256 173.649 1.00 75.17  ? 478 PHE A N   1 
ATOM   3310 C  CA  . PHE A 1 478 ? 161.008 182.440 173.141 1.00 75.17  ? 478 PHE A CA  1 
ATOM   3311 C  C   . PHE A 1 478 ? 162.187 182.071 172.251 1.00 75.17  ? 478 PHE A C   1 
ATOM   3312 O  O   . PHE A 1 478 ? 162.409 182.710 171.213 1.00 75.17  ? 478 PHE A O   1 
ATOM   3313 C  CB  . PHE A 1 478 ? 161.474 183.306 174.308 1.00 75.17  ? 478 PHE A CB  1 
ATOM   3314 C  CG  . PHE A 1 478 ? 161.566 184.764 173.983 1.00 75.17  ? 478 PHE A CG  1 
ATOM   3315 C  CD1 . PHE A 1 478 ? 160.453 185.460 173.546 1.00 75.17  ? 478 PHE A CD1 1 
ATOM   3316 C  CD2 . PHE A 1 478 ? 162.764 185.443 174.126 1.00 75.17  ? 478 PHE A CD2 1 
ATOM   3317 C  CE1 . PHE A 1 478 ? 160.534 186.808 173.251 1.00 75.17  ? 478 PHE A CE1 1 
ATOM   3318 C  CE2 . PHE A 1 478 ? 162.853 186.789 173.832 1.00 75.17  ? 478 PHE A CE2 1 
ATOM   3319 C  CZ  . PHE A 1 478 ? 161.736 187.473 173.395 1.00 75.17  ? 478 PHE A CZ  1 
ATOM   3320 N  N   . VAL A 1 479 ? 162.955 181.046 172.637 1.00 72.05  ? 479 VAL A N   1 
ATOM   3321 C  CA  . VAL A 1 479 ? 164.097 180.639 171.823 1.00 72.05  ? 479 VAL A CA  1 
ATOM   3322 C  C   . VAL A 1 479 ? 163.635 180.091 170.476 1.00 72.05  ? 479 VAL A C   1 
ATOM   3323 O  O   . VAL A 1 479 ? 164.218 180.416 169.435 1.00 72.05  ? 479 VAL A O   1 
ATOM   3324 C  CB  . VAL A 1 479 ? 164.975 179.635 172.591 1.00 72.05  ? 479 VAL A CB  1 
ATOM   3325 C  CG1 . VAL A 1 479 ? 166.030 179.034 171.685 1.00 72.05  ? 479 VAL A CG1 1 
ATOM   3326 C  CG2 . VAL A 1 479 ? 165.659 180.334 173.746 1.00 72.05  ? 479 VAL A CG2 1 
ATOM   3327 N  N   . ALA A 1 480 ? 162.565 179.290 170.459 1.00 73.36  ? 480 ALA A N   1 
ATOM   3328 C  CA  . ALA A 1 480 ? 162.049 178.786 169.188 1.00 73.36  ? 480 ALA A CA  1 
ATOM   3329 C  C   . ALA A 1 480 ? 161.475 179.905 168.327 1.00 73.36  ? 480 ALA A C   1 
ATOM   3330 O  O   . ALA A 1 480 ? 161.656 179.900 167.101 1.00 73.36  ? 480 ALA A O   1 
ATOM   3331 C  CB  . ALA A 1 480 ? 160.995 177.712 169.435 1.00 73.36  ? 480 ALA A CB  1 
ATOM   3332 N  N   . ILE A 1 481 ? 160.788 180.872 168.951 1.00 73.10  ? 481 ILE A N   1 
ATOM   3333 C  CA  . ILE A 1 481 ? 160.248 182.018 168.220 1.00 73.10  ? 481 ILE A CA  1 
ATOM   3334 C  C   . ILE A 1 481 ? 161.367 182.784 167.533 1.00 73.10  ? 481 ILE A C   1 
ATOM   3335 O  O   . ILE A 1 481 ? 161.307 183.052 166.328 1.00 73.10  ? 481 ILE A O   1 
ATOM   3336 C  CB  . ILE A 1 481 ? 159.447 182.932 169.167 1.00 73.10  ? 481 ILE A CB  1 
ATOM   3337 C  CG1 . ILE A 1 481 ? 158.035 182.403 169.367 1.00 73.10  ? 481 ILE A CG1 1 
ATOM   3338 C  CG2 . ILE A 1 481 ? 159.358 184.350 168.627 1.00 73.10  ? 481 ILE A CG2 1 
ATOM   3339 C  CD1 . ILE A 1 481 ? 157.351 182.948 170.594 1.00 73.10  ? 481 ILE A CD1 1 
ATOM   3340 N  N   . PHE A 1 482 ? 162.422 183.112 168.278 1.00 77.13  ? 482 PHE A N   1 
ATOM   3341 C  CA  . PHE A 1 482 ? 163.486 183.916 167.691 1.00 77.13  ? 482 PHE A CA  1 
ATOM   3342 C  C   . PHE A 1 482 ? 164.335 183.117 166.712 1.00 77.13  ? 482 PHE A C   1 
ATOM   3343 O  O   . PHE A 1 482 ? 164.814 183.682 165.726 1.00 77.13  ? 482 PHE A O   1 
ATOM   3344 C  CB  . PHE A 1 482 ? 164.339 184.538 168.790 1.00 77.13  ? 482 PHE A CB  1 
ATOM   3345 C  CG  . PHE A 1 482 ? 163.872 185.901 169.198 1.00 77.13  ? 482 PHE A CG  1 
ATOM   3346 C  CD1 . PHE A 1 482 ? 162.542 186.121 169.513 1.00 77.13  ? 482 PHE A CD1 1 
ATOM   3347 C  CD2 . PHE A 1 482 ? 164.752 186.962 169.254 1.00 77.13  ? 482 PHE A CD2 1 
ATOM   3348 C  CE1 . PHE A 1 482 ? 162.101 187.375 169.880 1.00 77.13  ? 482 PHE A CE1 1 
ATOM   3349 C  CE2 . PHE A 1 482 ? 164.319 188.220 169.623 1.00 77.13  ? 482 PHE A CE2 1 
ATOM   3350 C  CZ  . PHE A 1 482 ? 162.991 188.426 169.936 1.00 77.13  ? 482 PHE A CZ  1 
ATOM   3351 N  N   . GLU A 1 483 ? 164.477 181.808 166.928 1.00 79.37  ? 483 GLU A N   1 
ATOM   3352 C  CA  . GLU A 1 483 ? 165.169 180.945 165.976 1.00 79.37  ? 483 GLU A CA  1 
ATOM   3353 C  C   . GLU A 1 483 ? 164.454 180.917 164.630 1.00 79.37  ? 483 GLU A C   1 
ATOM   3354 O  O   . GLU A 1 483 ? 165.066 181.149 163.576 1.00 79.37  ? 483 GLU A O   1 
ATOM   3355 C  CB  . GLU A 1 483 ? 165.258 179.538 166.562 1.00 79.37  ? 483 GLU A CB  1 
ATOM   3356 C  CG  . GLU A 1 483 ? 166.254 178.623 165.914 1.00 79.37  ? 483 GLU A CG  1 
ATOM   3357 C  CD  . GLU A 1 483 ? 166.536 177.404 166.765 1.00 79.37  ? 483 GLU A CD  1 
ATOM   3358 O  OE1 . GLU A 1 483 ? 165.656 176.524 166.843 1.00 79.37  ? 483 GLU A OE1 1 
ATOM   3359 O  OE2 . GLU A 1 483 ? 167.631 177.327 167.358 1.00 79.37  ? 483 GLU A OE2 1 
ATOM   3360 N  N   . CYS A 1 484 ? 163.148 180.644 164.651 1.00 73.58  ? 484 CYS A N   1 
ATOM   3361 C  CA  . CYS A 1 484 ? 162.403 180.556 163.404 1.00 73.58  ? 484 CYS A CA  1 
ATOM   3362 C  C   . CYS A 1 484 ? 162.248 181.918 162.741 1.00 73.58  ? 484 CYS A C   1 
ATOM   3363 O  O   . CYS A 1 484 ? 162.274 182.000 161.510 1.00 73.58  ? 484 CYS A O   1 
ATOM   3364 C  CB  . CYS A 1 484 ? 161.044 179.912 163.652 1.00 73.58  ? 484 CYS A CB  1 
ATOM   3365 S  SG  . CYS A 1 484 ? 161.088 178.111 163.604 1.00 73.58  ? 484 CYS A SG  1 
ATOM   3366 N  N   . ILE A 1 485 ? 162.113 182.995 163.525 1.00 74.36  ? 485 ILE A N   1 
ATOM   3367 C  CA  . ILE A 1 485 ? 162.072 184.335 162.943 1.00 74.36  ? 485 ILE A CA  1 
ATOM   3368 C  C   . ILE A 1 485 ? 163.400 184.676 162.279 1.00 74.36  ? 485 ILE A C   1 
ATOM   3369 O  O   . ILE A 1 485 ? 163.423 185.206 161.161 1.00 74.36  ? 485 ILE A O   1 
ATOM   3370 C  CB  . ILE A 1 485 ? 161.668 185.377 164.004 1.00 74.36  ? 485 ILE A CB  1 
ATOM   3371 C  CG1 . ILE A 1 485 ? 160.166 185.288 164.280 1.00 74.36  ? 485 ILE A CG1 1 
ATOM   3372 C  CG2 . ILE A 1 485 ? 162.045 186.786 163.580 1.00 74.36  ? 485 ILE A CG2 1 
ATOM   3373 C  CD1 . ILE A 1 485 ? 159.697 186.166 165.413 1.00 74.36  ? 485 ILE A CD1 1 
ATOM   3374 N  N   . CYS A 1 486 ? 164.520 184.338 162.930 1.00 76.74  ? 486 CYS A N   1 
ATOM   3375 C  CA  . CYS A 1 486 ? 165.840 184.573 162.349 1.00 76.74  ? 486 CYS A CA  1 
ATOM   3376 C  C   . CYS A 1 486 ? 165.998 183.857 161.016 1.00 76.74  ? 486 CYS A C   1 
ATOM   3377 O  O   . CYS A 1 486 ? 166.361 184.479 160.010 1.00 76.74  ? 486 CYS A O   1 
ATOM   3378 C  CB  . CYS A 1 486 ? 166.926 184.117 163.321 1.00 76.74  ? 486 CYS A CB  1 
ATOM   3379 S  SG  . CYS A 1 486 ? 168.595 184.137 162.632 1.00 76.74  ? 486 CYS A SG  1 
ATOM   3380 N  N   . ILE A 1 487 ? 165.675 182.562 160.979 1.00 77.91  ? 487 ILE A N   1 
ATOM   3381 C  CA  . ILE A 1 487 ? 165.866 181.790 159.752 1.00 77.91  ? 487 ILE A CA  1 
ATOM   3382 C  C   . ILE A 1 487 ? 164.906 182.255 158.660 1.00 77.91  ? 487 ILE A C   1 
ATOM   3383 O  O   . ILE A 1 487 ? 165.313 182.488 157.515 1.00 77.91  ? 487 ILE A O   1 
ATOM   3384 C  CB  . ILE A 1 487 ? 165.722 180.285 160.035 1.00 77.91  ? 487 ILE A CB  1 
ATOM   3385 C  CG1 . ILE A 1 487 ? 166.997 179.750 160.683 1.00 77.91  ? 487 ILE A CG1 1 
ATOM   3386 C  CG2 . ILE A 1 487 ? 165.442 179.515 158.758 1.00 77.91  ? 487 ILE A CG2 1 
ATOM   3387 C  CD1 . ILE A 1 487 ? 168.231 179.920 159.830 1.00 77.91  ? 487 ILE A CD1 1 
ATOM   3388 N  N   . GLY A 1 488 ? 163.627 182.435 158.997 1.00 78.28  ? 488 GLY A N   1 
ATOM   3389 C  CA  . GLY A 1 488 ? 162.639 182.737 157.979 1.00 78.28  ? 488 GLY A CA  1 
ATOM   3390 C  C   . GLY A 1 488 ? 162.594 184.185 157.539 1.00 78.28  ? 488 GLY A C   1 
ATOM   3391 O  O   . GLY A 1 488 ? 161.962 184.486 156.522 1.00 78.28  ? 488 GLY A O   1 
ATOM   3392 N  N   . TRP A 1 489 ? 163.235 185.088 158.267 1.00 79.01  ? 489 TRP A N   1 
ATOM   3393 C  CA  . TRP A 1 489 ? 163.143 186.473 157.826 1.00 79.01  ? 489 TRP A CA  1 
ATOM   3394 C  C   . TRP A 1 489 ? 164.490 187.166 157.697 1.00 79.01  ? 489 TRP A C   1 
ATOM   3395 O  O   . TRP A 1 489 ? 164.662 187.982 156.790 1.00 79.01  ? 489 TRP A O   1 
ATOM   3396 C  CB  . TRP A 1 489 ? 162.240 187.256 158.783 1.00 79.01  ? 489 TRP A CB  1 
ATOM   3397 C  CG  . TRP A 1 489 ? 160.842 186.732 158.824 1.00 79.01  ? 489 TRP A CG  1 
ATOM   3398 C  CD1 . TRP A 1 489 ? 160.297 185.928 159.777 1.00 79.01  ? 489 TRP A CD1 1 
ATOM   3399 C  CD2 . TRP A 1 489 ? 159.805 186.981 157.868 1.00 79.01  ? 489 TRP A CD2 1 
ATOM   3400 N  NE1 . TRP A 1 489 ? 158.986 185.656 159.475 1.00 79.01  ? 489 TRP A NE1 1 
ATOM   3401 C  CE2 . TRP A 1 489 ? 158.659 186.293 158.307 1.00 79.01  ? 489 TRP A CE2 1 
ATOM   3402 C  CE3 . TRP A 1 489 ? 159.735 187.720 156.684 1.00 79.01  ? 489 TRP A CE3 1 
ATOM   3403 C  CZ2 . TRP A 1 489 ? 157.458 186.319 157.605 1.00 79.01  ? 489 TRP A CZ2 1 
ATOM   3404 C  CZ3 . TRP A 1 489 ? 158.541 187.745 155.988 1.00 79.01  ? 489 TRP A CZ3 1 
ATOM   3405 C  CH2 . TRP A 1 489 ? 157.419 187.049 156.450 1.00 79.01  ? 489 TRP A CH2 1 
ATOM   3406 N  N   . VAL A 1 490 ? 165.446 186.872 158.571 1.00 82.15  ? 490 VAL A N   1 
ATOM   3407 C  CA  . VAL A 1 490 ? 166.715 187.590 158.543 1.00 82.15  ? 490 VAL A CA  1 
ATOM   3408 C  C   . VAL A 1 490 ? 167.711 186.916 157.612 1.00 82.15  ? 490 VAL A C   1 
ATOM   3409 O  O   . VAL A 1 490 ? 168.275 187.556 156.721 1.00 82.15  ? 490 VAL A O   1 
ATOM   3410 C  CB  . VAL A 1 490 ? 167.273 187.724 159.972 1.00 82.15  ? 490 VAL A CB  1 
ATOM   3411 C  CG1 . VAL A 1 490 ? 168.445 188.682 159.987 1.00 82.15  ? 490 VAL A CG1 1 
ATOM   3412 C  CG2 . VAL A 1 490 ? 166.182 188.200 160.909 1.00 82.15  ? 490 VAL A CG2 1 
ATOM   3413 N  N   . TYR A 1 491 ? 167.942 185.616 157.797 1.00 85.97  ? 491 TYR A N   1 
ATOM   3414 C  CA  . TYR A 1 491 ? 168.798 184.882 156.875 1.00 85.97  ? 491 TYR A CA  1 
ATOM   3415 C  C   . TYR A 1 491 ? 168.110 184.619 155.546 1.00 85.97  ? 491 TYR A C   1 
ATOM   3416 O  O   . TYR A 1 491 ? 168.793 184.446 154.532 1.00 85.97  ? 491 TYR A O   1 
ATOM   3417 C  CB  . TYR A 1 491 ? 169.236 183.559 157.501 1.00 85.97  ? 491 TYR A CB  1 
ATOM   3418 C  CG  . TYR A 1 491 ? 170.312 182.837 156.725 1.00 85.97  ? 491 TYR A CG  1 
ATOM   3419 C  CD1 . TYR A 1 491 ? 171.530 183.444 156.462 1.00 85.97  ? 491 TYR A CD1 1 
ATOM   3420 C  CD2 . TYR A 1 491 ? 170.109 181.547 156.257 1.00 85.97  ? 491 TYR A CD2 1 
ATOM   3421 C  CE1 . TYR A 1 491 ? 172.516 182.787 155.753 1.00 85.97  ? 491 TYR A CE1 1 
ATOM   3422 C  CE2 . TYR A 1 491 ? 171.089 180.882 155.547 1.00 85.97  ? 491 TYR A CE2 1 
ATOM   3423 C  CZ  . TYR A 1 491 ? 172.290 181.508 155.299 1.00 85.97  ? 491 TYR A CZ  1 
ATOM   3424 O  OH  . TYR A 1 491 ? 173.272 180.853 154.594 1.00 85.97  ? 491 TYR A OH  1 
ATOM   3425 N  N   . GLY A 1 492 ? 166.783 184.593 155.527 1.00 85.14  ? 492 GLY A N   1 
ATOM   3426 C  CA  . GLY A 1 492 ? 166.050 184.307 154.312 1.00 85.14  ? 492 GLY A CA  1 
ATOM   3427 C  C   . GLY A 1 492 ? 165.764 182.830 154.161 1.00 85.14  ? 492 GLY A C   1 
ATOM   3428 O  O   . GLY A 1 492 ? 166.681 182.006 154.227 1.00 85.14  ? 492 GLY A O   1 
ATOM   3429 N  N   . SER A 1 493 ? 164.492 182.478 153.970 1.00 85.12  ? 493 SER A N   1 
ATOM   3430 C  CA  . SER A 1 493 ? 164.139 181.072 153.827 1.00 85.12  ? 493 SER A CA  1 
ATOM   3431 C  C   . SER A 1 493 ? 164.601 180.509 152.491 1.00 85.12  ? 493 SER A C   1 
ATOM   3432 O  O   . SER A 1 493 ? 164.884 179.311 152.395 1.00 85.12  ? 493 SER A O   1 
ATOM   3433 C  CB  . SER A 1 493 ? 162.633 180.886 153.986 1.00 85.12  ? 493 SER A CB  1 
ATOM   3434 O  OG  . SER A 1 493 ? 162.289 179.512 153.984 1.00 85.12  ? 493 SER A OG  1 
ATOM   3435 N  N   . ASN A 1 494 ? 164.680 181.349 151.455 1.00 91.09  ? 494 ASN A N   1 
ATOM   3436 C  CA  . ASN A 1 494 ? 165.163 180.884 150.158 1.00 91.09  ? 494 ASN A CA  1 
ATOM   3437 C  C   . ASN A 1 494 ? 166.643 180.525 150.212 1.00 91.09  ? 494 ASN A C   1 
ATOM   3438 O  O   . ASN A 1 494 ? 167.057 179.498 149.661 1.00 91.09  ? 494 ASN A O   1 
ATOM   3439 C  CB  . ASN A 1 494 ? 164.907 181.945 149.091 1.00 91.09  ? 494 ASN A CB  1 
ATOM   3440 C  CG  . ASN A 1 494 ? 165.292 183.335 149.551 1.00 91.09  ? 494 ASN A CG  1 
ATOM   3441 O  OD1 . ASN A 1 494 ? 165.725 183.524 150.687 1.00 91.09  ? 494 ASN A OD1 1 
ATOM   3442 N  ND2 . ASN A 1 494 ? 165.138 184.316 148.670 1.00 91.09  ? 494 ASN A ND2 1 
ATOM   3443 N  N   . ARG A 1 495 ? 167.452 181.354 150.880 1.00 86.86  ? 495 ARG A N   1 
ATOM   3444 C  CA  . ARG A 1 495 ? 168.877 181.068 151.008 1.00 86.86  ? 495 ARG A CA  1 
ATOM   3445 C  C   . ARG A 1 495 ? 169.121 179.808 151.828 1.00 86.86  ? 495 ARG A C   1 
ATOM   3446 O  O   . ARG A 1 495 ? 169.975 178.984 151.476 1.00 86.86  ? 495 ARG A O   1 
ATOM   3447 C  CB  . ARG A 1 495 ? 169.598 182.258 151.636 1.00 86.86  ? 495 ARG A CB  1 
ATOM   3448 C  CG  . ARG A 1 495 ? 171.006 182.468 151.116 1.00 86.86  ? 495 ARG A CG  1 
ATOM   3449 C  CD  . ARG A 1 495 ? 171.794 183.416 152.002 1.00 86.86  ? 495 ARG A CD  1 
ATOM   3450 N  NE  . ARG A 1 495 ? 170.957 184.468 152.564 1.00 86.86  ? 495 ARG A NE  1 
ATOM   3451 C  CZ  . ARG A 1 495 ? 170.745 185.643 151.987 1.00 86.86  ? 495 ARG A CZ  1 
ATOM   3452 N  NH1 . ARG A 1 495 ? 171.295 185.950 150.824 1.00 86.86  ? 495 ARG A NH1 1 
ATOM   3453 N  NH2 . ARG A 1 495 ? 169.961 186.531 152.591 1.00 86.86  ? 495 ARG A NH2 1 
ATOM   3454 N  N   . PHE A 1 496 ? 168.370 179.630 152.916 1.00 85.18  ? 496 PHE A N   1 
ATOM   3455 C  CA  . PHE A 1 496 ? 168.542 178.430 153.724 1.00 85.18  ? 496 PHE A CA  1 
ATOM   3456 C  C   . PHE A 1 496 ? 168.033 177.189 153.003 1.00 85.18  ? 496 PHE A C   1 
ATOM   3457 O  O   . PHE A 1 496 ? 168.612 176.109 153.154 1.00 85.18  ? 496 PHE A O   1 
ATOM   3458 C  CB  . PHE A 1 496 ? 167.840 178.584 155.069 1.00 85.18  ? 496 PHE A CB  1 
ATOM   3459 C  CG  . PHE A 1 496 ? 168.252 177.557 156.074 1.00 85.18  ? 496 PHE A CG  1 
ATOM   3460 C  CD1 . PHE A 1 496 ? 169.588 177.255 156.256 1.00 85.18  ? 496 PHE A CD1 1 
ATOM   3461 C  CD2 . PHE A 1 496 ? 167.309 176.875 156.816 1.00 85.18  ? 496 PHE A CD2 1 
ATOM   3462 C  CE1 . PHE A 1 496 ? 169.978 176.305 157.172 1.00 85.18  ? 496 PHE A CE1 1 
ATOM   3463 C  CE2 . PHE A 1 496 ? 167.692 175.921 157.733 1.00 85.18  ? 496 PHE A CE2 1 
ATOM   3464 C  CZ  . PHE A 1 496 ? 169.029 175.637 157.911 1.00 85.18  ? 496 PHE A CZ  1 
ATOM   3465 N  N   . SER A 1 497 ? 166.959 177.320 152.219 1.00 87.60  ? 497 SER A N   1 
ATOM   3466 C  CA  . SER A 1 497 ? 166.488 176.196 151.417 1.00 87.60  ? 497 SER A CA  1 
ATOM   3467 C  C   . SER A 1 497 ? 167.509 175.819 150.353 1.00 87.60  ? 497 SER A C   1 
ATOM   3468 O  O   . SER A 1 497 ? 167.703 174.634 150.064 1.00 87.60  ? 497 SER A O   1 
ATOM   3469 C  CB  . SER A 1 497 ? 165.146 176.534 150.774 1.00 87.60  ? 497 SER A CB  1 
ATOM   3470 O  OG  . SER A 1 497 ? 165.334 177.281 149.586 1.00 87.60  ? 497 SER A OG  1 
ATOM   3471 N  N   . GLU A 1 498 ? 168.177 176.815 149.769 1.00 89.51  ? 498 GLU A N   1 
ATOM   3472 C  CA  . GLU A 1 498 ? 169.254 176.538 148.825 1.00 89.51  ? 498 GLU A CA  1 
ATOM   3473 C  C   . GLU A 1 498 ? 170.425 175.840 149.511 1.00 89.51  ? 498 GLU A C   1 
ATOM   3474 O  O   . GLU A 1 498 ? 171.028 174.923 148.940 1.00 89.51  ? 498 GLU A O   1 
ATOM   3475 C  CB  . GLU A 1 498 ? 169.710 177.839 148.171 1.00 89.51  ? 498 GLU A CB  1 
ATOM   3476 C  CG  . GLU A 1 498 ? 170.991 177.720 147.388 1.00 89.51  ? 498 GLU A CG  1 
ATOM   3477 C  CD  . GLU A 1 498 ? 171.688 179.044 147.220 1.00 89.51  ? 498 GLU A CD  1 
ATOM   3478 O  OE1 . GLU A 1 498 ? 171.023 180.093 147.353 1.00 89.51  ? 498 GLU A OE1 1 
ATOM   3479 O  OE2 . GLU A 1 498 ? 172.904 179.032 146.952 1.00 89.51  ? 498 GLU A OE2 1 
ATOM   3480 N  N   . ASP A 1 499 ? 170.756 176.259 150.737 1.00 88.90  ? 499 ASP A N   1 
ATOM   3481 C  CA  . ASP A 1 499 ? 171.816 175.592 151.493 1.00 88.90  ? 499 ASP A CA  1 
ATOM   3482 C  C   . ASP A 1 499 ? 171.453 174.143 151.802 1.00 88.90  ? 499 ASP A C   1 
ATOM   3483 O  O   . ASP A 1 499 ? 172.302 173.248 151.715 1.00 88.90  ? 499 ASP A O   1 
ATOM   3484 C  CB  . ASP A 1 499 ? 172.097 176.353 152.786 1.00 88.90  ? 499 ASP A CB  1 
ATOM   3485 C  CG  . ASP A 1 499 ? 172.713 177.710 152.540 1.00 88.90  ? 499 ASP A CG  1 
ATOM   3486 O  OD1 . ASP A 1 499 ? 173.403 177.873 151.515 1.00 88.90  ? 499 ASP A OD1 1 
ATOM   3487 O  OD2 . ASP A 1 499 ? 172.508 178.617 153.372 1.00 88.90  ? 499 ASP A OD2 1 
ATOM   3488 N  N   . ILE A 1 500 ? 170.191 173.897 152.159 1.00 86.85  ? 500 ILE A N   1 
ATOM   3489 C  CA  . ILE A 1 500 ? 169.724 172.537 152.412 1.00 86.85  ? 500 ILE A CA  1 
ATOM   3490 C  C   . ILE A 1 500 ? 169.770 171.706 151.132 1.00 86.85  ? 500 ILE A C   1 
ATOM   3491 O  O   . ILE A 1 500 ? 170.134 170.523 151.157 1.00 86.85  ? 500 ILE A O   1 
ATOM   3492 C  CB  . ILE A 1 500 ? 168.315 172.581 153.031 1.00 86.85  ? 500 ILE A CB  1 
ATOM   3493 C  CG1 . ILE A 1 500 ? 168.395 173.095 154.468 1.00 86.85  ? 500 ILE A CG1 1 
ATOM   3494 C  CG2 . ILE A 1 500 ? 167.644 171.221 153.002 1.00 86.85  ? 500 ILE A CG2 1 
ATOM   3495 C  CD1 . ILE A 1 500 ? 167.059 173.432 155.071 1.00 86.85  ? 500 ILE A CD1 1 
ATOM   3496 N  N   . ARG A 1 501 ? 169.421 172.315 149.995 1.00 84.60  ? 501 ARG A N   1 
ATOM   3497 C  CA  . ARG A 1 501 ? 169.515 171.626 148.711 1.00 84.60  ? 501 ARG A CA  1 
ATOM   3498 C  C   . ARG A 1 501 ? 170.958 171.270 148.380 1.00 84.60  ? 501 ARG A C   1 
ATOM   3499 O  O   . ARG A 1 501 ? 171.230 170.196 147.834 1.00 84.60  ? 501 ARG A O   1 
ATOM   3500 C  CB  . ARG A 1 501 ? 168.910 172.493 147.607 1.00 84.60  ? 501 ARG A CB  1 
ATOM   3501 C  CG  . ARG A 1 501 ? 168.797 171.809 146.251 1.00 84.60  ? 501 ARG A CG  1 
ATOM   3502 C  CD  . ARG A 1 501 ? 169.856 172.305 145.275 1.00 84.60  ? 501 ARG A CD  1 
ATOM   3503 N  NE  . ARG A 1 501 ? 169.924 171.480 144.076 1.00 84.60  ? 501 ARG A NE  1 
ATOM   3504 C  CZ  . ARG A 1 501 ? 171.009 171.335 143.328 1.00 84.60  ? 501 ARG A CZ  1 
ATOM   3505 N  NH1 . ARG A 1 501 ? 172.144 171.941 143.634 1.00 84.60  ? 501 ARG A NH1 1 
ATOM   3506 N  NH2 . ARG A 1 501 ? 170.954 170.563 142.248 1.00 84.60  ? 501 ARG A NH2 1 
ATOM   3507 N  N   . ASP A 1 502 ? 171.893 172.167 148.688 1.00 86.85  ? 502 ASP A N   1 
ATOM   3508 C  CA  . ASP A 1 502 ? 173.303 171.866 148.465 1.00 86.85  ? 502 ASP A CA  1 
ATOM   3509 C  C   . ASP A 1 502 ? 173.803 170.784 149.411 1.00 86.85  ? 502 ASP A C   1 
ATOM   3510 O  O   . ASP A 1 502 ? 174.690 170.004 149.048 1.00 86.85  ? 502 ASP A O   1 
ATOM   3511 C  CB  . ASP A 1 502 ? 174.142 173.131 148.625 1.00 86.85  ? 502 ASP A CB  1 
ATOM   3512 C  CG  . ASP A 1 502 ? 175.543 172.970 148.080 1.00 86.85  ? 502 ASP A CG  1 
ATOM   3513 O  OD1 . ASP A 1 502 ? 175.761 172.054 147.261 1.00 86.85  ? 502 ASP A OD1 1 
ATOM   3514 O  OD2 . ASP A 1 502 ? 176.429 173.757 148.473 1.00 86.85  ? 502 ASP A OD2 1 
ATOM   3515 N  N   . MET A 1 503 ? 173.248 170.721 150.621 1.00 94.88  ? 503 MET A N   1 
ATOM   3516 C  CA  . MET A 1 503 ? 173.697 169.747 151.609 1.00 94.88  ? 503 MET A CA  1 
ATOM   3517 C  C   . MET A 1 503 ? 173.169 168.350 151.305 1.00 94.88  ? 503 MET A C   1 
ATOM   3518 O  O   . MET A 1 503 ? 173.944 167.417 151.068 1.00 94.88  ? 503 MET A O   1 
ATOM   3519 C  CB  . MET A 1 503 ? 173.242 170.180 153.002 1.00 94.88  ? 503 MET A CB  1 
ATOM   3520 C  CG  . MET A 1 503 ? 174.179 171.125 153.707 1.00 94.88  ? 503 MET A CG  1 
ATOM   3521 S  SD  . MET A 1 503 ? 173.335 171.883 155.099 1.00 94.88  ? 503 MET A SD  1 
ATOM   3522 C  CE  . MET A 1 503 ? 172.724 170.436 155.952 1.00 94.88  ? 503 MET A CE  1 
ATOM   3523 N  N   . ILE A 1 504 ? 171.845 168.190 151.309 1.00 91.67  ? 504 ILE A N   1 
ATOM   3524 C  CA  . ILE A 1 504 ? 171.227 166.869 151.246 1.00 91.67  ? 504 ILE A CA  1 
ATOM   3525 C  C   . ILE A 1 504 ? 170.773 166.485 149.846 1.00 91.67  ? 504 ILE A C   1 
ATOM   3526 O  O   . ILE A 1 504 ? 170.452 165.307 149.617 1.00 91.67  ? 504 ILE A O   1 
ATOM   3527 C  CB  . ILE A 1 504 ? 170.039 166.771 152.227 1.00 91.67  ? 504 ILE A CB  1 
ATOM   3528 C  CG1 . ILE A 1 504 ? 168.818 167.504 151.670 1.00 91.67  ? 504 ILE A CG1 1 
ATOM   3529 C  CG2 . ILE A 1 504 ? 170.424 167.339 153.580 1.00 91.67  ? 504 ILE A CG2 1 
ATOM   3530 C  CD1 . ILE A 1 504 ? 167.622 167.486 152.592 1.00 91.67  ? 504 ILE A CD1 1 
ATOM   3531 N  N   . GLY A 1 505 ? 170.733 167.423 148.906 1.00 87.29  ? 505 GLY A N   1 
ATOM   3532 C  CA  . GLY A 1 505 ? 170.339 167.092 147.553 1.00 87.29  ? 505 GLY A CA  1 
ATOM   3533 C  C   . GLY A 1 505 ? 169.050 167.748 147.106 1.00 87.29  ? 505 GLY A C   1 
ATOM   3534 O  O   . GLY A 1 505 ? 168.931 168.164 145.951 1.00 87.29  ? 505 GLY A O   1 
ATOM   3535 N  N   . PHE A 1 506 ? 168.078 167.850 148.004 1.00 88.93  ? 506 PHE A N   1 
ATOM   3536 C  CA  . PHE A 1 506 ? 166.771 168.374 147.648 1.00 88.93  ? 506 PHE A CA  1 
ATOM   3537 C  C   . PHE A 1 506 ? 166.343 169.446 148.638 1.00 88.93  ? 506 PHE A C   1 
ATOM   3538 O  O   . PHE A 1 506 ? 166.676 169.371 149.824 1.00 88.93  ? 506 PHE A O   1 
ATOM   3539 C  CB  . PHE A 1 506 ? 165.717 167.252 147.599 1.00 88.93  ? 506 PHE A CB  1 
ATOM   3540 C  CG  . PHE A 1 506 ? 165.490 166.552 148.914 1.00 88.93  ? 506 PHE A CG  1 
ATOM   3541 C  CD1 . PHE A 1 506 ? 166.332 165.532 149.330 1.00 88.93  ? 506 PHE A CD1 1 
ATOM   3542 C  CD2 . PHE A 1 506 ? 164.412 166.888 149.716 1.00 88.93  ? 506 PHE A CD2 1 
ATOM   3543 C  CE1 . PHE A 1 506 ? 166.119 164.882 150.528 1.00 88.93  ? 506 PHE A CE1 1 
ATOM   3544 C  CE2 . PHE A 1 506 ? 164.194 166.241 150.916 1.00 88.93  ? 506 PHE A CE2 1 
ATOM   3545 C  CZ  . PHE A 1 506 ? 165.049 165.236 151.321 1.00 88.93  ? 506 PHE A CZ  1 
ATOM   3546 N  N   . PRO A 1 507 ? 165.605 170.455 148.179 1.00 83.26  ? 507 PRO A N   1 
ATOM   3547 C  CA  . PRO A 1 507 ? 165.156 171.522 149.076 1.00 83.26  ? 507 PRO A CA  1 
ATOM   3548 C  C   . PRO A 1 507 ? 164.049 171.034 149.993 1.00 83.26  ? 507 PRO A C   1 
ATOM   3549 O  O   . PRO A 1 507 ? 163.498 169.944 149.780 1.00 83.26  ? 507 PRO A O   1 
ATOM   3550 C  CB  . PRO A 1 507 ? 164.645 172.595 148.103 1.00 83.26  ? 507 PRO A CB  1 
ATOM   3551 C  CG  . PRO A 1 507 ? 164.198 171.824 146.927 1.00 83.26  ? 507 PRO A CG  1 
ATOM   3552 C  CD  . PRO A 1 507 ? 165.208 170.722 146.785 1.00 83.26  ? 507 PRO A CD  1 
ATOM   3553 N  N   . PRO A 1 508 ? 163.715 171.795 151.036 1.00 84.56  ? 508 PRO A N   1 
ATOM   3554 C  CA  . PRO A 1 508 ? 162.556 171.444 151.852 1.00 84.56  ? 508 PRO A CA  1 
ATOM   3555 C  C   . PRO A 1 508 ? 161.282 171.517 151.037 1.00 84.56  ? 508 PRO A C   1 
ATOM   3556 O  O   . PRO A 1 508 ? 161.196 172.276 150.053 1.00 84.56  ? 508 PRO A O   1 
ATOM   3557 C  CB  . PRO A 1 508 ? 162.576 172.503 152.963 1.00 84.56  ? 508 PRO A CB  1 
ATOM   3558 C  CG  . PRO A 1 508 ? 163.982 172.923 153.050 1.00 84.56  ? 508 PRO A CG  1 
ATOM   3559 C  CD  . PRO A 1 508 ? 164.512 172.867 151.657 1.00 84.56  ? 508 PRO A CD  1 
ATOM   3560 N  N   . PRO A 1 509 ? 160.246 170.750 151.419 1.00 89.66  ? 509 PRO A N   1 
ATOM   3561 C  CA  . PRO A 1 509 ? 159.054 170.627 150.563 1.00 89.66  ? 509 PRO A CA  1 
ATOM   3562 C  C   . PRO A 1 509 ? 158.113 171.825 150.599 1.00 89.66  ? 509 PRO A C   1 
ATOM   3563 O  O   . PRO A 1 509 ? 156.945 171.698 150.216 1.00 89.66  ? 509 PRO A O   1 
ATOM   3564 C  CB  . PRO A 1 509 ? 158.355 169.373 151.114 1.00 89.66  ? 509 PRO A CB  1 
ATOM   3565 C  CG  . PRO A 1 509 ? 159.331 168.741 152.073 1.00 89.66  ? 509 PRO A CG  1 
ATOM   3566 C  CD  . PRO A 1 509 ? 160.175 169.851 152.580 1.00 89.66  ? 509 PRO A CD  1 
ATOM   3567 N  N   . SER A 1 510 ? 158.598 172.952 151.132 1.00 88.11  ? 510 SER A N   1 
ATOM   3568 C  CA  . SER A 1 510 ? 157.958 174.267 151.214 1.00 88.11  ? 510 SER A CA  1 
ATOM   3569 C  C   . SER A 1 510 ? 156.840 174.314 152.250 1.00 88.11  ? 510 SER A C   1 
ATOM   3570 O  O   . SER A 1 510 ? 156.400 175.402 152.638 1.00 88.11  ? 510 SER A O   1 
ATOM   3571 C  CB  . SER A 1 510 ? 157.432 174.724 149.848 1.00 88.11  ? 510 SER A CB  1 
ATOM   3572 O  OG  . SER A 1 510 ? 156.428 175.712 149.997 1.00 88.11  ? 510 SER A OG  1 
ATOM   3573 N  N   . LEU A 1 511 ? 156.434 173.157 152.771 1.00 88.59  ? 511 LEU A N   1 
ATOM   3574 C  CA  . LEU A 1 511 ? 155.591 173.158 153.958 1.00 88.59  ? 511 LEU A CA  1 
ATOM   3575 C  C   . LEU A 1 511 ? 156.408 173.537 155.182 1.00 88.59  ? 511 LEU A C   1 
ATOM   3576 O  O   . LEU A 1 511 ? 155.968 174.343 156.007 1.00 88.59  ? 511 LEU A O   1 
ATOM   3577 C  CB  . LEU A 1 511 ? 154.935 171.792 154.144 1.00 88.59  ? 511 LEU A CB  1 
ATOM   3578 C  CG  . LEU A 1 511 ? 153.793 171.758 155.157 1.00 88.59  ? 511 LEU A CG  1 
ATOM   3579 C  CD1 . LEU A 1 511 ? 152.674 172.697 154.730 1.00 88.59  ? 511 LEU A CD1 1 
ATOM   3580 C  CD2 . LEU A 1 511 ? 153.275 170.340 155.331 1.00 88.59  ? 511 LEU A CD2 1 
ATOM   3581 N  N   . ILE A 1 512 ? 157.622 172.990 155.291 1.00 86.32  ? 512 ILE A N   1 
ATOM   3582 C  CA  . ILE A 1 512 ? 158.548 173.406 156.336 1.00 86.32  ? 512 ILE A CA  1 
ATOM   3583 C  C   . ILE A 1 512 ? 158.976 174.855 156.129 1.00 86.32  ? 512 ILE A C   1 
ATOM   3584 O  O   . ILE A 1 512 ? 159.193 175.590 157.101 1.00 86.32  ? 512 ILE A O   1 
ATOM   3585 C  CB  . ILE A 1 512 ? 159.749 172.444 156.379 1.00 86.32  ? 512 ILE A CB  1 
ATOM   3586 C  CG1 . ILE A 1 512 ? 159.255 171.001 156.496 1.00 86.32  ? 512 ILE A CG1 1 
ATOM   3587 C  CG2 . ILE A 1 512 ? 160.662 172.767 157.544 1.00 86.32  ? 512 ILE A CG2 1 
ATOM   3588 C  CD1 . ILE A 1 512 ? 160.344 169.994 156.802 1.00 86.32  ? 512 ILE A CD1 1 
ATOM   3589 N  N   . LYS A 1 513 ? 159.079 175.301 154.873 1.00 83.81  ? 513 LYS A N   1 
ATOM   3590 C  CA  . LYS A 1 513 ? 159.407 176.699 154.606 1.00 83.81  ? 513 LYS A CA  1 
ATOM   3591 C  C   . LYS A 1 513 ? 158.309 177.631 155.108 1.00 83.81  ? 513 LYS A C   1 
ATOM   3592 O  O   . LYS A 1 513 ? 158.587 178.603 155.822 1.00 83.81  ? 513 LYS A O   1 
ATOM   3593 C  CB  . LYS A 1 513 ? 159.645 176.909 153.111 1.00 83.81  ? 513 LYS A CB  1 
ATOM   3594 C  CG  . LYS A 1 513 ? 161.074 176.652 152.663 1.00 83.81  ? 513 LYS A CG  1 
ATOM   3595 C  CD  . LYS A 1 513 ? 161.152 176.333 151.175 1.00 83.81  ? 513 LYS A CD  1 
ATOM   3596 C  CE  . LYS A 1 513 ? 160.436 177.378 150.331 1.00 83.81  ? 513 LYS A CE  1 
ATOM   3597 N  NZ  . LYS A 1 513 ? 160.993 178.744 150.530 1.00 83.81  ? 513 LYS A NZ  1 
ATOM   3598 N  N   . TRP A 1 514 ? 157.050 177.338 154.765 1.00 87.04  ? 514 TRP A N   1 
ATOM   3599 C  CA  . TRP A 1 514 ? 155.954 178.163 155.267 1.00 87.04  ? 514 TRP A CA  1 
ATOM   3600 C  C   . TRP A 1 514 ? 155.793 178.032 156.776 1.00 87.04  ? 514 TRP A C   1 
ATOM   3601 O  O   . TRP A 1 514 ? 155.322 178.971 157.429 1.00 87.04  ? 514 TRP A O   1 
ATOM   3602 C  CB  . TRP A 1 514 ? 154.645 177.807 154.560 1.00 87.04  ? 514 TRP A CB  1 
ATOM   3603 C  CG  . TRP A 1 514 ? 154.543 178.271 153.122 1.00 87.04  ? 514 TRP A CG  1 
ATOM   3604 C  CD1 . TRP A 1 514 ? 154.166 177.513 152.051 1.00 87.04  ? 514 TRP A CD1 1 
ATOM   3605 C  CD2 . TRP A 1 514 ? 154.770 179.599 152.608 1.00 87.04  ? 514 TRP A CD2 1 
ATOM   3606 N  NE1 . TRP A 1 514 ? 154.172 178.270 150.905 1.00 87.04  ? 514 TRP A NE1 1 
ATOM   3607 C  CE2 . TRP A 1 514 ? 154.535 179.552 151.220 1.00 87.04  ? 514 TRP A CE2 1 
ATOM   3608 C  CE3 . TRP A 1 514 ? 155.156 180.816 153.184 1.00 87.04  ? 514 TRP A CE3 1 
ATOM   3609 C  CZ2 . TRP A 1 514 ? 154.675 180.671 150.401 1.00 87.04  ? 514 TRP A CZ2 1 
ATOM   3610 C  CZ3 . TRP A 1 514 ? 155.297 181.923 152.369 1.00 87.04  ? 514 TRP A CZ3 1 
ATOM   3611 C  CH2 . TRP A 1 514 ? 155.056 181.844 150.994 1.00 87.04  ? 514 TRP A CH2 1 
ATOM   3612 N  N   . CYS A 1 515 ? 156.182 176.887 157.343 1.00 82.87  ? 515 CYS A N   1 
ATOM   3613 C  CA  . CYS A 1 515 ? 156.210 176.750 158.794 1.00 82.87  ? 515 CYS A CA  1 
ATOM   3614 C  C   . CYS A 1 515 ? 157.241 177.682 159.413 1.00 82.87  ? 515 CYS A C   1 
ATOM   3615 O  O   . CYS A 1 515 ? 156.997 178.276 160.469 1.00 82.87  ? 515 CYS A O   1 
ATOM   3616 C  CB  . CYS A 1 515 ? 156.495 175.300 159.175 1.00 82.87  ? 515 CYS A CB  1 
ATOM   3617 S  SG  . CYS A 1 515 ? 155.044 174.226 159.162 1.00 82.87  ? 515 CYS A SG  1 
ATOM   3618 N  N   . TRP A 1 516 ? 158.402 177.816 158.772 1.00 80.84  ? 516 TRP A N   1 
ATOM   3619 C  CA  . TRP A 1 516 ? 159.418 178.739 159.263 1.00 80.84  ? 516 TRP A CA  1 
ATOM   3620 C  C   . TRP A 1 516 ? 158.955 180.186 159.149 1.00 80.84  ? 516 TRP A C   1 
ATOM   3621 O  O   . TRP A 1 516 ? 159.239 181.001 160.033 1.00 80.84  ? 516 TRP A O   1 
ATOM   3622 C  CB  . TRP A 1 516 ? 160.726 178.538 158.504 1.00 80.84  ? 516 TRP A CB  1 
ATOM   3623 C  CG  . TRP A 1 516 ? 161.404 177.246 158.810 1.00 80.84  ? 516 TRP A CG  1 
ATOM   3624 C  CD1 . TRP A 1 516 ? 161.203 176.453 159.897 1.00 80.84  ? 516 TRP A CD1 1 
ATOM   3625 C  CD2 . TRP A 1 516 ? 162.400 176.594 158.016 1.00 80.84  ? 516 TRP A CD2 1 
ATOM   3626 N  NE1 . TRP A 1 516 ? 162.010 175.345 159.830 1.00 80.84  ? 516 TRP A NE1 1 
ATOM   3627 C  CE2 . TRP A 1 516 ? 162.757 175.410 158.684 1.00 80.84  ? 516 TRP A CE2 1 
ATOM   3628 C  CE3 . TRP A 1 516 ? 163.024 176.898 156.804 1.00 80.84  ? 516 TRP A CE3 1 
ATOM   3629 C  CZ2 . TRP A 1 516 ? 163.710 174.530 158.182 1.00 80.84  ? 516 TRP A CZ2 1 
ATOM   3630 C  CZ3 . TRP A 1 516 ? 163.967 176.023 156.306 1.00 80.84  ? 516 TRP A CZ3 1 
ATOM   3631 C  CH2 . TRP A 1 516 ? 164.301 174.853 156.993 1.00 80.84  ? 516 TRP A CH2 1 
ATOM   3632 N  N   . MET A 1 517 ? 158.253 180.531 158.066 1.00 78.76  ? 517 MET A N   1 
ATOM   3633 C  CA  . MET A 1 517 ? 157.788 181.912 157.922 1.00 78.76  ? 517 MET A CA  1 
ATOM   3634 C  C   . MET A 1 517 ? 156.659 182.233 158.896 1.00 78.76  ? 517 MET A C   1 
ATOM   3635 O  O   . MET A 1 517 ? 156.814 183.080 159.783 1.00 78.76  ? 517 MET A O   1 
ATOM   3636 C  CB  . MET A 1 517 ? 157.335 182.212 156.488 1.00 78.76  ? 517 MET A CB  1 
ATOM   3637 C  CG  . MET A 1 517 ? 158.200 181.670 155.377 1.00 78.76  ? 517 MET A CG  1 
ATOM   3638 S  SD  . MET A 1 517 ? 159.686 182.649 155.125 1.00 78.76  ? 517 MET A SD  1 
ATOM   3639 C  CE  . MET A 1 517 ? 159.045 183.972 154.105 1.00 78.76  ? 517 MET A CE  1 
ATOM   3640 N  N   . ILE A 1 518 ? 155.511 181.570 158.752 1.00 79.27  ? 518 ILE A N   1 
ATOM   3641 C  CA  . ILE A 1 518 ? 154.291 182.095 159.359 1.00 79.27  ? 518 ILE A CA  1 
ATOM   3642 C  C   . ILE A 1 518 ? 153.646 181.132 160.348 1.00 79.27  ? 518 ILE A C   1 
ATOM   3643 O  O   . ILE A 1 518 ? 152.898 181.561 161.233 1.00 79.27  ? 518 ILE A O   1 
ATOM   3644 C  CB  . ILE A 1 518 ? 153.271 182.496 158.275 1.00 79.27  ? 518 ILE A CB  1 
ATOM   3645 C  CG1 . ILE A 1 518 ? 152.898 181.292 157.406 1.00 79.27  ? 518 ILE A CG1 1 
ATOM   3646 C  CG2 . ILE A 1 518 ? 153.809 183.635 157.421 1.00 79.27  ? 518 ILE A CG2 1 
ATOM   3647 C  CD1 . ILE A 1 518 ? 151.731 181.545 156.477 1.00 79.27  ? 518 ILE A CD1 1 
ATOM   3648 N  N   . MET A 1 519 ? 153.908 179.833 160.216 1.00 80.68  ? 519 MET A N   1 
ATOM   3649 C  CA  . MET A 1 519 ? 153.147 178.883 161.020 1.00 80.68  ? 519 MET A CA  1 
ATOM   3650 C  C   . MET A 1 519 ? 153.755 178.702 162.405 1.00 80.68  ? 519 MET A C   1 
ATOM   3651 O  O   . MET A 1 519 ? 153.086 178.940 163.414 1.00 80.68  ? 519 MET A O   1 
ATOM   3652 C  CB  . MET A 1 519 ? 153.031 177.539 160.301 1.00 80.68  ? 519 MET A CB  1 
ATOM   3653 C  CG  . MET A 1 519 ? 151.910 176.665 160.825 1.00 80.68  ? 519 MET A CG  1 
ATOM   3654 S  SD  . MET A 1 519 ? 150.292 177.268 160.312 1.00 80.68  ? 519 MET A SD  1 
ATOM   3655 C  CE  . MET A 1 519 ? 149.426 177.292 161.878 1.00 80.68  ? 519 MET A CE  1 
ATOM   3656 N  N   . THR A 1 520 ? 155.015 178.266 162.475 1.00 75.35  ? 520 THR A N   1 
ATOM   3657 C  CA  . THR A 1 520 ? 155.640 178.020 163.776 1.00 75.35  ? 520 THR A CA  1 
ATOM   3658 C  C   . THR A 1 520 ? 155.820 179.280 164.625 1.00 75.35  ? 520 THR A C   1 
ATOM   3659 O  O   . THR A 1 520 ? 155.403 179.254 165.798 1.00 75.35  ? 520 THR A O   1 
ATOM   3660 C  CB  . THR A 1 520 ? 156.959 177.258 163.583 1.00 75.35  ? 520 THR A CB  1 
ATOM   3661 O  OG1 . THR A 1 520 ? 156.678 175.905 163.215 1.00 75.35  ? 520 THR A OG1 1 
ATOM   3662 C  CG2 . THR A 1 520 ? 157.777 177.261 164.860 1.00 75.35  ? 520 THR A CG2 1 
ATOM   3663 N  N   . PRO A 1 521 ? 156.406 180.393 164.139 1.00 73.76  ? 521 PRO A N   1 
ATOM   3664 C  CA  . PRO A 1 521 ? 156.453 181.588 164.999 1.00 73.76  ? 521 PRO A CA  1 
ATOM   3665 C  C   . PRO A 1 521 ? 155.085 182.150 165.311 1.00 73.76  ? 521 PRO A C   1 
ATOM   3666 O  O   . PRO A 1 521 ? 154.883 182.666 166.414 1.00 73.76  ? 521 PRO A O   1 
ATOM   3667 C  CB  . PRO A 1 521 ? 157.296 182.586 164.193 1.00 73.76  ? 521 PRO A CB  1 
ATOM   3668 C  CG  . PRO A 1 521 ? 157.972 181.795 163.173 1.00 73.76  ? 521 PRO A CG  1 
ATOM   3669 C  CD  . PRO A 1 521 ? 157.031 180.698 162.837 1.00 73.76  ? 521 PRO A CD  1 
ATOM   3670 N  N   . GLY A 1 522 ? 154.131 182.032 164.386 1.00 71.72  ? 522 GLY A N   1 
ATOM   3671 C  CA  . GLY A 1 522 ? 152.785 182.506 164.663 1.00 71.72  ? 522 GLY A CA  1 
ATOM   3672 C  C   . GLY A 1 522 ? 152.117 181.738 165.787 1.00 71.72  ? 522 GLY A C   1 
ATOM   3673 O  O   . GLY A 1 522 ? 151.574 182.332 166.721 1.00 71.72  ? 522 GLY A O   1 
ATOM   3674 N  N   . ILE A 1 523 ? 152.192 180.405 165.739 1.00 75.68  ? 523 ILE A N   1 
ATOM   3675 C  CA  . ILE A 1 523 ? 151.546 179.606 166.776 1.00 75.68  ? 523 ILE A CA  1 
ATOM   3676 C  C   . ILE A 1 523 ? 152.294 179.728 168.100 1.00 75.68  ? 523 ILE A C   1 
ATOM   3677 O  O   . ILE A 1 523 ? 151.667 179.763 169.166 1.00 75.68  ? 523 ILE A O   1 
ATOM   3678 C  CB  . ILE A 1 523 ? 151.374 178.136 166.325 1.00 75.68  ? 523 ILE A CB  1 
ATOM   3679 C  CG1 . ILE A 1 523 ? 150.443 177.386 167.275 1.00 75.68  ? 523 ILE A CG1 1 
ATOM   3680 C  CG2 . ILE A 1 523 ? 152.690 177.389 166.229 1.00 75.68  ? 523 ILE A CG2 1 
ATOM   3681 C  CD1 . ILE A 1 523 ? 149.995 176.049 166.743 1.00 75.68  ? 523 ILE A CD1 1 
ATOM   3682 N  N   . CYS A 1 524 ? 153.625 179.857 168.072 1.00 72.39  ? 524 CYS A N   1 
ATOM   3683 C  CA  . CYS A 1 524 ? 154.359 179.946 169.329 1.00 72.39  ? 524 CYS A CA  1 
ATOM   3684 C  C   . CYS A 1 524 ? 154.183 181.315 169.976 1.00 72.39  ? 524 CYS A C   1 
ATOM   3685 O  O   . CYS A 1 524 ? 154.060 181.412 171.202 1.00 72.39  ? 524 CYS A O   1 
ATOM   3686 C  CB  . CYS A 1 524 ? 155.831 179.624 169.097 1.00 72.39  ? 524 CYS A CB  1 
ATOM   3687 S  SG  . CYS A 1 524 ? 156.201 177.861 168.983 1.00 72.39  ? 524 CYS A SG  1 
ATOM   3688 N  N   . ALA A 1 525 ? 154.131 182.383 169.174 1.00 72.36  ? 525 ALA A N   1 
ATOM   3689 C  CA  . ALA A 1 525 ? 153.806 183.697 169.712 1.00 72.36  ? 525 ALA A CA  1 
ATOM   3690 C  C   . ALA A 1 525 ? 152.374 183.754 170.218 1.00 72.36  ? 525 ALA A C   1 
ATOM   3691 O  O   . ALA A 1 525 ? 152.107 184.413 171.228 1.00 72.36  ? 525 ALA A O   1 
ATOM   3692 C  CB  . ALA A 1 525 ? 154.037 184.774 168.653 1.00 72.36  ? 525 ALA A CB  1 
ATOM   3693 N  N   . GLY A 1 526 ? 151.446 183.075 169.538 1.00 75.53  ? 526 GLY A N   1 
ATOM   3694 C  CA  . GLY A 1 526 ? 150.084 183.003 170.037 1.00 75.53  ? 526 GLY A CA  1 
ATOM   3695 C  C   . GLY A 1 526 ? 149.989 182.296 171.375 1.00 75.53  ? 526 GLY A C   1 
ATOM   3696 O  O   . GLY A 1 526 ? 149.282 182.752 172.274 1.00 75.53  ? 526 GLY A O   1 
ATOM   3697 N  N   . ILE A 1 527 ? 150.720 181.189 171.531 1.00 72.22  ? 527 ILE A N   1 
ATOM   3698 C  CA  . ILE A 1 527 ? 150.724 180.467 172.802 1.00 72.22  ? 527 ILE A CA  1 
ATOM   3699 C  C   . ILE A 1 527 ? 151.386 181.303 173.895 1.00 72.22  ? 527 ILE A C   1 
ATOM   3700 O  O   . ILE A 1 527 ? 150.921 181.325 175.041 1.00 72.22  ? 527 ILE A O   1 
ATOM   3701 C  CB  . ILE A 1 527 ? 151.399 179.094 172.627 1.00 72.22  ? 527 ILE A CB  1 
ATOM   3702 C  CG1 . ILE A 1 527 ? 150.546 178.192 171.736 1.00 72.22  ? 527 ILE A CG1 1 
ATOM   3703 C  CG2 . ILE A 1 527 ? 151.608 178.407 173.955 1.00 72.22  ? 527 ILE A CG2 1 
ATOM   3704 C  CD1 . ILE A 1 527 ? 149.091 178.139 172.127 1.00 72.22  ? 527 ILE A CD1 1 
ATOM   3705 N  N   . PHE A 1 528 ? 152.456 182.027 173.553 1.00 74.86  ? 528 PHE A N   1 
ATOM   3706 C  CA  . PHE A 1 528 ? 153.120 182.906 174.515 1.00 74.86  ? 528 PHE A CA  1 
ATOM   3707 C  C   . PHE A 1 528 ? 152.187 184.015 174.995 1.00 74.86  ? 528 PHE A C   1 
ATOM   3708 O  O   . PHE A 1 528 ? 152.062 184.261 176.203 1.00 74.86  ? 528 PHE A O   1 
ATOM   3709 C  CB  . PHE A 1 528 ? 154.374 183.502 173.876 1.00 74.86  ? 528 PHE A CB  1 
ATOM   3710 C  CG  . PHE A 1 528 ? 155.432 183.912 174.857 1.00 74.86  ? 528 PHE A CG  1 
ATOM   3711 C  CD1 . PHE A 1 528 ? 155.304 185.076 175.596 1.00 74.86  ? 528 PHE A CD1 1 
ATOM   3712 C  CD2 . PHE A 1 528 ? 156.574 183.149 175.014 1.00 74.86  ? 528 PHE A CD2 1 
ATOM   3713 C  CE1 . PHE A 1 528 ? 156.285 185.458 176.489 1.00 74.86  ? 528 PHE A CE1 1 
ATOM   3714 C  CE2 . PHE A 1 528 ? 157.562 183.529 175.901 1.00 74.86  ? 528 PHE A CE2 1 
ATOM   3715 C  CZ  . PHE A 1 528 ? 157.415 184.684 176.642 1.00 74.86  ? 528 PHE A CZ  1 
ATOM   3716 N  N   . ILE A 1 529 ? 151.510 184.685 174.060 1.00 75.61  ? 529 ILE A N   1 
ATOM   3717 C  CA  . ILE A 1 529 ? 150.598 185.765 174.424 1.00 75.61  ? 529 ILE A CA  1 
ATOM   3718 C  C   . ILE A 1 529 ? 149.406 185.218 175.202 1.00 75.61  ? 529 ILE A C   1 
ATOM   3719 O  O   . ILE A 1 529 ? 148.956 185.827 176.180 1.00 75.61  ? 529 ILE A O   1 
ATOM   3720 C  CB  . ILE A 1 529 ? 150.167 186.536 173.162 1.00 75.61  ? 529 ILE A CB  1 
ATOM   3721 C  CG1 . ILE A 1 529 ? 151.361 187.289 172.575 1.00 75.61  ? 529 ILE A CG1 1 
ATOM   3722 C  CG2 . ILE A 1 529 ? 149.039 187.511 173.460 1.00 75.61  ? 529 ILE A CG2 1 
ATOM   3723 C  CD1 . ILE A 1 529 ? 151.919 188.356 173.489 1.00 75.61  ? 529 ILE A CD1 1 
ATOM   3724 N  N   . PHE A 1 530 ? 148.907 184.043 174.808 1.00 77.64  ? 530 PHE A N   1 
ATOM   3725 C  CA  . PHE A 1 530 ? 147.772 183.432 175.488 1.00 77.64  ? 530 PHE A CA  1 
ATOM   3726 C  C   . PHE A 1 530 ? 148.132 183.018 176.910 1.00 77.64  ? 530 PHE A C   1 
ATOM   3727 O  O   . PHE A 1 530 ? 147.293 183.095 177.814 1.00 77.64  ? 530 PHE A O   1 
ATOM   3728 C  CB  . PHE A 1 530 ? 147.282 182.236 174.673 1.00 77.64  ? 530 PHE A CB  1 
ATOM   3729 C  CG  . PHE A 1 530 ? 146.095 181.540 175.259 1.00 77.64  ? 530 PHE A CG  1 
ATOM   3730 C  CD1 . PHE A 1 530 ? 145.021 182.263 175.750 1.00 77.64  ? 530 PHE A CD1 1 
ATOM   3731 C  CD2 . PHE A 1 530 ? 146.040 180.159 175.290 1.00 77.64  ? 530 PHE A CD2 1 
ATOM   3732 C  CE1 . PHE A 1 530 ? 143.925 181.620 176.284 1.00 77.64  ? 530 PHE A CE1 1 
ATOM   3733 C  CE2 . PHE A 1 530 ? 144.947 179.510 175.821 1.00 77.64  ? 530 PHE A CE2 1 
ATOM   3734 C  CZ  . PHE A 1 530 ? 143.887 180.241 176.318 1.00 77.64  ? 530 PHE A CZ  1 
ATOM   3735 N  N   . PHE A 1 531 ? 149.371 182.577 177.128 1.00 76.74  ? 531 PHE A N   1 
ATOM   3736 C  CA  . PHE A 1 531 ? 149.823 182.317 178.490 1.00 76.74  ? 531 PHE A CA  1 
ATOM   3737 C  C   . PHE A 1 531 ? 149.965 183.611 179.275 1.00 76.74  ? 531 PHE A C   1 
ATOM   3738 O  O   . PHE A 1 531 ? 149.677 183.649 180.476 1.00 76.74  ? 531 PHE A O   1 
ATOM   3739 C  CB  . PHE A 1 531 ? 151.149 181.559 178.477 1.00 76.74  ? 531 PHE A CB  1 
ATOM   3740 C  CG  . PHE A 1 531 ? 151.668 181.226 179.847 1.00 76.74  ? 531 PHE A CG  1 
ATOM   3741 C  CD1 . PHE A 1 531 ? 151.143 180.162 180.557 1.00 76.74  ? 531 PHE A CD1 1 
ATOM   3742 C  CD2 . PHE A 1 531 ? 152.671 181.982 180.428 1.00 76.74  ? 531 PHE A CD2 1 
ATOM   3743 C  CE1 . PHE A 1 531 ? 151.614 179.853 181.818 1.00 76.74  ? 531 PHE A CE1 1 
ATOM   3744 C  CE2 . PHE A 1 531 ? 153.147 181.676 181.685 1.00 76.74  ? 531 PHE A CE2 1 
ATOM   3745 C  CZ  . PHE A 1 531 ? 152.617 180.611 182.382 1.00 76.74  ? 531 PHE A CZ  1 
ATOM   3746 N  N   . LEU A 1 532 ? 150.417 184.679 178.616 1.00 76.76  ? 532 LEU A N   1 
ATOM   3747 C  CA  . LEU A 1 532 ? 150.705 185.913 179.337 1.00 76.76  ? 532 LEU A CA  1 
ATOM   3748 C  C   . LEU A 1 532 ? 149.428 186.633 179.760 1.00 76.76  ? 532 LEU A C   1 
ATOM   3749 O  O   . LEU A 1 532 ? 149.379 187.239 180.837 1.00 76.76  ? 532 LEU A O   1 
ATOM   3750 C  CB  . LEU A 1 532 ? 151.585 186.822 178.482 1.00 76.76  ? 532 LEU A CB  1 
ATOM   3751 C  CG  . LEU A 1 532 ? 153.095 186.634 178.655 1.00 76.76  ? 532 LEU A CG  1 
ATOM   3752 C  CD1 . LEU A 1 532 ? 153.855 187.801 178.047 1.00 76.76  ? 532 LEU A CD1 1 
ATOM   3753 C  CD2 . LEU A 1 532 ? 153.471 186.448 180.117 1.00 76.76  ? 532 LEU A CD2 1 
ATOM   3754 N  N   . ILE A 1 533 ? 148.381 186.584 178.933 1.00 77.76  ? 533 ILE A N   1 
ATOM   3755 C  CA  . ILE A 1 533 ? 147.187 187.360 179.262 1.00 77.76  ? 533 ILE A CA  1 
ATOM   3756 C  C   . ILE A 1 533 ? 146.287 186.604 180.237 1.00 77.76  ? 533 ILE A C   1 
ATOM   3757 O  O   . ILE A 1 533 ? 145.743 187.197 181.174 1.00 77.76  ? 533 ILE A O   1 
ATOM   3758 C  CB  . ILE A 1 533 ? 146.431 187.796 177.987 1.00 77.76  ? 533 ILE A CB  1 
ATOM   3759 C  CG1 . ILE A 1 533 ? 145.998 186.610 177.123 1.00 77.76  ? 533 ILE A CG1 1 
ATOM   3760 C  CG2 . ILE A 1 533 ? 147.285 188.747 177.165 1.00 77.76  ? 533 ILE A CG2 1 
ATOM   3761 C  CD1 . ILE A 1 533 ? 144.999 186.977 176.052 1.00 77.76  ? 533 ILE A CD1 1 
ATOM   3762 N  N   . LYS A 1 534 ? 146.108 185.296 180.045 1.00 77.87  ? 534 LYS A N   1 
ATOM   3763 C  CA  . LYS A 1 534 ? 145.304 184.481 180.955 1.00 77.87  ? 534 LYS A CA  1 
ATOM   3764 C  C   . LYS A 1 534 ? 146.250 183.702 181.861 1.00 77.87  ? 534 LYS A C   1 
ATOM   3765 O  O   . LYS A 1 534 ? 146.469 182.503 181.700 1.00 77.87  ? 534 LYS A O   1 
ATOM   3766 C  CB  . LYS A 1 534 ? 144.370 183.560 180.177 1.00 77.87  ? 534 LYS A CB  1 
ATOM   3767 C  CG  . LYS A 1 534 ? 143.553 184.260 179.106 1.00 77.87  ? 534 LYS A CG  1 
ATOM   3768 C  CD  . LYS A 1 534 ? 142.668 185.350 179.697 1.00 77.87  ? 534 LYS A CD  1 
ATOM   3769 C  CE  . LYS A 1 534 ? 141.638 184.783 180.665 1.00 77.87  ? 534 LYS A CE  1 
ATOM   3770 N  NZ  . LYS A 1 534 ? 140.379 185.577 180.660 1.00 77.87  ? 534 LYS A NZ  1 
ATOM   3771 N  N   . TYR A 1 535 ? 146.816 184.407 182.835 1.00 85.03  ? 535 TYR A N   1 
ATOM   3772 C  CA  . TYR A 1 535 ? 147.770 183.787 183.743 1.00 85.03  ? 535 TYR A CA  1 
ATOM   3773 C  C   . TYR A 1 535 ? 147.045 182.871 184.719 1.00 85.03  ? 535 TYR A C   1 
ATOM   3774 O  O   . TYR A 1 535 ? 146.046 183.260 185.332 1.00 85.03  ? 535 TYR A O   1 
ATOM   3775 C  CB  . TYR A 1 535 ? 148.555 184.859 184.499 1.00 85.03  ? 535 TYR A CB  1 
ATOM   3776 C  CG  . TYR A 1 535 ? 149.858 184.375 185.097 1.00 85.03  ? 535 TYR A CG  1 
ATOM   3777 C  CD1 . TYR A 1 535 ? 149.880 183.648 186.281 1.00 85.03  ? 535 TYR A CD1 1 
ATOM   3778 C  CD2 . TYR A 1 535 ? 151.067 184.644 184.474 1.00 85.03  ? 535 TYR A CD2 1 
ATOM   3779 C  CE1 . TYR A 1 535 ? 151.067 183.205 186.825 1.00 85.03  ? 535 TYR A CE1 1 
ATOM   3780 C  CE2 . TYR A 1 535 ? 152.258 184.206 185.011 1.00 85.03  ? 535 TYR A CE2 1 
ATOM   3781 C  CZ  . TYR A 1 535 ? 152.253 183.487 186.186 1.00 85.03  ? 535 TYR A CZ  1 
ATOM   3782 O  OH  . TYR A 1 535 ? 153.441 183.049 186.721 1.00 85.03  ? 535 TYR A OH  1 
ATOM   3783 N  N   . LYS A 1 536 ? 147.552 181.651 184.860 1.00 87.72  ? 536 LYS A N   1 
ATOM   3784 C  CA  . LYS A 1 536 ? 147.059 180.707 185.840 1.00 87.72  ? 536 LYS A CA  1 
ATOM   3785 C  C   . LYS A 1 536 ? 148.204 180.302 186.756 1.00 87.72  ? 536 LYS A C   1 
ATOM   3786 O  O   . LYS A 1 536 ? 149.250 179.852 186.266 1.00 87.72  ? 536 LYS A O   1 
ATOM   3787 C  CB  . LYS A 1 536 ? 146.462 179.468 185.164 1.00 87.72  ? 536 LYS A CB  1 
ATOM   3788 C  CG  . LYS A 1 536 ? 145.104 179.715 184.538 1.00 87.72  ? 536 LYS A CG  1 
ATOM   3789 C  CD  . LYS A 1 536 ? 144.052 179.990 185.598 1.00 87.72  ? 536 LYS A CD  1 
ATOM   3790 C  CE  . LYS A 1 536 ? 143.737 178.739 186.400 1.00 87.72  ? 536 LYS A CE  1 
ATOM   3791 N  NZ  . LYS A 1 536 ? 143.626 177.536 185.528 1.00 87.72  ? 536 LYS A NZ  1 
ATOM   3792 N  N   . PRO A 1 537 ? 148.062 180.463 188.070 1.00 84.93  ? 537 PRO A N   1 
ATOM   3793 C  CA  . PRO A 1 537 ? 149.178 180.176 188.975 1.00 84.93  ? 537 PRO A CA  1 
ATOM   3794 C  C   . PRO A 1 537 ? 149.508 178.692 189.029 1.00 84.93  ? 537 PRO A C   1 
ATOM   3795 O  O   . PRO A 1 537 ? 148.648 177.828 188.846 1.00 84.93  ? 537 PRO A O   1 
ATOM   3796 C  CB  . PRO A 1 537 ? 148.674 180.687 190.329 1.00 84.93  ? 537 PRO A CB  1 
ATOM   3797 C  CG  . PRO A 1 537 ? 147.195 180.632 190.224 1.00 84.93  ? 537 PRO A CG  1 
ATOM   3798 C  CD  . PRO A 1 537 ? 146.866 180.929 188.791 1.00 84.93  ? 537 PRO A CD  1 
ATOM   3799 N  N   . LEU A 1 538 ? 150.782 178.409 189.283 1.00 81.98  ? 538 LEU A N   1 
ATOM   3800 C  CA  . LEU A 1 538 ? 151.304 177.049 189.284 1.00 81.98  ? 538 LEU A CA  1 
ATOM   3801 C  C   . LEU A 1 538 ? 151.103 176.420 190.657 1.00 81.98  ? 538 LEU A C   1 
ATOM   3802 O  O   . LEU A 1 538 ? 151.429 177.032 191.678 1.00 81.98  ? 538 LEU A O   1 
ATOM   3803 C  CB  . LEU A 1 538 ? 152.788 177.059 188.924 1.00 81.98  ? 538 LEU A CB  1 
ATOM   3804 C  CG  . LEU A 1 538 ? 153.479 175.708 188.783 1.00 81.98  ? 538 LEU A CG  1 
ATOM   3805 C  CD1 . LEU A 1 538 ? 152.879 174.955 187.618 1.00 81.98  ? 538 LEU A CD1 1 
ATOM   3806 C  CD2 . LEU A 1 538 ? 154.967 175.896 188.599 1.00 81.98  ? 538 LEU A CD2 1 
ATOM   3807 N  N   . LYS A 1 539 ? 150.559 175.205 190.681 1.00 77.38  ? 539 LYS A N   1 
ATOM   3808 C  CA  . LYS A 1 539 ? 150.351 174.458 191.914 1.00 77.38  ? 539 LYS A CA  1 
ATOM   3809 C  C   . LYS A 1 539 ? 151.053 173.113 191.808 1.00 77.38  ? 539 LYS A C   1 
ATOM   3810 O  O   . LYS A 1 539 ? 150.940 172.433 190.783 1.00 77.38  ? 539 LYS A O   1 
ATOM   3811 C  CB  . LYS A 1 539 ? 148.862 174.260 192.203 1.00 77.38  ? 539 LYS A CB  1 
ATOM   3812 C  CG  . LYS A 1 539 ? 147.973 175.418 191.782 1.00 77.38  ? 539 LYS A CG  1 
ATOM   3813 C  CD  . LYS A 1 539 ? 146.777 175.547 192.710 1.00 77.38  ? 539 LYS A CD  1 
ATOM   3814 C  CE  . LYS A 1 539 ? 145.826 176.628 192.238 1.00 77.38  ? 539 LYS A CE  1 
ATOM   3815 N  NZ  . LYS A 1 539 ? 144.936 176.132 191.155 1.00 77.38  ? 539 LYS A NZ  1 
ATOM   3816 N  N   . TYR A 1 540 ? 151.790 172.741 192.858 1.00 76.18  ? 540 TYR A N   1 
ATOM   3817 C  CA  . TYR A 1 540 ? 152.581 171.515 192.848 1.00 76.18  ? 540 TYR A CA  1 
ATOM   3818 C  C   . TYR A 1 540 ? 151.731 170.250 192.767 1.00 76.18  ? 540 TYR A C   1 
ATOM   3819 O  O   . TYR A 1 540 ? 151.741 169.559 191.744 1.00 76.18  ? 540 TYR A O   1 
ATOM   3820 C  CB  . TYR A 1 540 ? 153.470 171.456 194.091 1.00 76.18  ? 540 TYR A CB  1 
ATOM   3821 C  CG  . TYR A 1 540 ? 154.203 170.148 194.239 1.00 76.18  ? 540 TYR A CG  1 
ATOM   3822 C  CD1 . TYR A 1 540 ? 155.219 169.800 193.362 1.00 76.18  ? 540 TYR A CD1 1 
ATOM   3823 C  CD2 . TYR A 1 540 ? 153.874 169.255 195.250 1.00 76.18  ? 540 TYR A CD2 1 
ATOM   3824 C  CE1 . TYR A 1 540 ? 155.890 168.602 193.489 1.00 76.18  ? 540 TYR A CE1 1 
ATOM   3825 C  CE2 . TYR A 1 540 ? 154.537 168.055 195.384 1.00 76.18  ? 540 TYR A CE2 1 
ATOM   3826 C  CZ  . TYR A 1 540 ? 155.544 167.735 194.500 1.00 76.18  ? 540 TYR A CZ  1 
ATOM   3827 O  OH  . TYR A 1 540 ? 156.208 166.542 194.628 1.00 76.18  ? 540 TYR A OH  1 
ATOM   3828 N  N   . ASN A 1 541 ? 150.987 169.939 193.822 1.00 80.42  ? 541 ASN A N   1 
ATOM   3829 C  CA  . ASN A 1 541 ? 150.083 168.787 193.819 1.00 80.42  ? 541 ASN A CA  1 
ATOM   3830 C  C   . ASN A 1 541 ? 148.675 169.220 193.435 1.00 80.42  ? 541 ASN A C   1 
ATOM   3831 O  O   . ASN A 1 541 ? 147.692 168.897 194.103 1.00 80.42  ? 541 ASN A O   1 
ATOM   3832 C  CB  . ASN A 1 541 ? 150.101 168.122 195.191 1.00 80.42  ? 541 ASN A CB  1 
ATOM   3833 C  CG  . ASN A 1 541 ? 149.694 166.661 195.151 1.00 80.42  ? 541 ASN A CG  1 
ATOM   3834 O  OD1 . ASN A 1 541 ? 148.705 166.289 194.521 1.00 80.42  ? 541 ASN A OD1 1 
ATOM   3835 N  ND2 . ASN A 1 541 ? 150.470 165.820 195.822 1.00 80.42  ? 541 ASN A ND2 1 
ATOM   3836 N  N   . ASN A 1 542 ? 148.599 170.038 192.380 1.00 77.77  ? 542 ASN A N   1 
ATOM   3837 C  CA  . ASN A 1 542 ? 147.393 170.620 191.788 1.00 77.77  ? 542 ASN A CA  1 
ATOM   3838 C  C   . ASN A 1 542 ? 146.636 171.559 192.729 1.00 77.77  ? 542 ASN A C   1 
ATOM   3839 O  O   . ASN A 1 542 ? 145.758 172.302 192.278 1.00 77.77  ? 542 ASN A O   1 
ATOM   3840 C  CB  . ASN A 1 542 ? 146.453 169.524 191.276 1.00 77.77  ? 542 ASN A CB  1 
ATOM   3841 C  CG  . ASN A 1 542 ? 146.679 169.204 189.815 1.00 77.77  ? 542 ASN A CG  1 
ATOM   3842 O  OD1 . ASN A 1 542 ? 146.881 170.100 188.995 1.00 77.77  ? 542 ASN A OD1 1 
ATOM   3843 N  ND2 . ASN A 1 542 ? 146.651 167.920 189.480 1.00 77.77  ? 542 ASN A ND2 1 
ATOM   3844 N  N   . ILE A 1 543 ? 146.985 171.559 194.020 1.00 81.76  ? 543 ILE A N   1 
ATOM   3845 C  CA  . ILE A 1 543 ? 146.591 172.553 195.014 1.00 81.76  ? 543 ILE A CA  1 
ATOM   3846 C  C   . ILE A 1 543 ? 147.789 172.895 195.910 1.00 81.76  ? 543 ILE A C   1 
ATOM   3847 O  O   . ILE A 1 543 ? 148.077 172.218 196.903 1.00 81.76  ? 543 ILE A O   1 
ATOM   3848 C  CB  . ILE A 1 543 ? 145.329 172.095 195.801 1.00 81.76  ? 543 ILE A CB  1 
ATOM   3849 C  CG1 . ILE A 1 543 ? 145.489 170.721 196.485 1.00 81.76  ? 543 ILE A CG1 1 
ATOM   3850 C  CG2 . ILE A 1 543 ? 144.047 172.172 194.962 1.00 81.76  ? 543 ILE A CG2 1 
ATOM   3851 C  CD1 . ILE A 1 543 ? 144.369 170.373 197.434 1.00 81.76  ? 543 ILE A CD1 1 
ATOM   3852 N  N   . TYR A 1 544 ? 148.526 173.926 195.546 1.00 79.34  ? 544 TYR A N   1 
ATOM   3853 C  CA  . TYR A 1 544 ? 149.491 174.461 196.503 1.00 79.34  ? 544 TYR A CA  1 
ATOM   3854 C  C   . TYR A 1 544 ? 149.436 175.976 196.614 1.00 79.34  ? 544 TYR A C   1 
ATOM   3855 O  O   . TYR A 1 544 ? 149.566 176.500 197.725 1.00 79.34  ? 544 TYR A O   1 
ATOM   3856 C  CB  . TYR A 1 544 ? 150.918 174.021 196.152 1.00 79.34  ? 544 TYR A CB  1 
ATOM   3857 C  CG  . TYR A 1 544 ? 151.967 174.672 197.021 1.00 79.34  ? 544 TYR A CG  1 
ATOM   3858 C  CD1 . TYR A 1 544 ? 151.973 174.487 198.397 1.00 79.34  ? 544 TYR A CD1 1 
ATOM   3859 C  CD2 . TYR A 1 544 ? 152.940 175.483 196.469 1.00 79.34  ? 544 TYR A CD2 1 
ATOM   3860 C  CE1 . TYR A 1 544 ? 152.930 175.090 199.193 1.00 79.34  ? 544 TYR A CE1 1 
ATOM   3861 C  CE2 . TYR A 1 544 ? 153.897 176.084 197.251 1.00 79.34  ? 544 TYR A CE2 1 
ATOM   3862 C  CZ  . TYR A 1 544 ? 153.889 175.888 198.609 1.00 79.34  ? 544 TYR A CZ  1 
ATOM   3863 O  OH  . TYR A 1 544 ? 154.850 176.500 199.375 1.00 79.34  ? 544 TYR A OH  1 
ATOM   3864 N  N   . THR A 1 545 ? 149.231 176.684 195.495 1.00 81.51  ? 545 THR A N   1 
ATOM   3865 C  CA  . THR A 1 545 ? 149.141 178.147 195.435 1.00 81.51  ? 545 THR A CA  1 
ATOM   3866 C  C   . THR A 1 545 ? 150.412 178.785 196.010 1.00 81.51  ? 545 THR A C   1 
ATOM   3867 O  O   . THR A 1 545 ? 150.433 179.322 197.121 1.00 81.51  ? 545 THR A O   1 
ATOM   3868 C  CB  . THR A 1 545 ? 147.870 178.660 196.128 1.00 81.51  ? 545 THR A CB  1 
ATOM   3869 O  OG1 . THR A 1 545 ? 146.742 177.925 195.641 1.00 81.51  ? 545 THR A OG1 1 
ATOM   3870 C  CG2 . THR A 1 545 ? 147.637 180.132 195.802 1.00 81.51  ? 545 THR A CG2 1 
ATOM   3871 N  N   . TYR A 1 546 ? 151.501 178.616 195.241 1.00 76.95  ? 546 TYR A N   1 
ATOM   3872 C  CA  . TYR A 1 546 ? 152.869 179.040 195.539 1.00 76.95  ? 546 TYR A CA  1 
ATOM   3873 C  C   . TYR A 1 546 ? 152.957 180.448 196.119 1.00 76.95  ? 546 TYR A C   1 
ATOM   3874 O  O   . TYR A 1 546 ? 152.145 181.316 195.773 1.00 76.95  ? 546 TYR A O   1 
ATOM   3875 C  CB  . TYR A 1 546 ? 153.733 178.998 194.279 1.00 76.95  ? 546 TYR A CB  1 
ATOM   3876 C  CG  . TYR A 1 546 ? 154.572 177.759 194.086 1.00 76.95  ? 546 TYR A CG  1 
ATOM   3877 C  CD1 . TYR A 1 546 ? 154.066 176.650 193.428 1.00 76.95  ? 546 TYR A CD1 1 
ATOM   3878 C  CD2 . TYR A 1 546 ? 155.874 177.703 194.557 1.00 76.95  ? 546 TYR A CD2 1 
ATOM   3879 C  CE1 . TYR A 1 546 ? 154.834 175.522 193.242 1.00 76.95  ? 546 TYR A CE1 1 
ATOM   3880 C  CE2 . TYR A 1 546 ? 156.647 176.579 194.378 1.00 76.95  ? 546 TYR A CE2 1 
ATOM   3881 C  CZ  . TYR A 1 546 ? 156.121 175.492 193.721 1.00 76.95  ? 546 TYR A CZ  1 
ATOM   3882 O  OH  . TYR A 1 546 ? 156.887 174.368 193.540 1.00 76.95  ? 546 TYR A OH  1 
ATOM   3883 N  N   . PRO A 1 547 ? 153.918 180.706 197.003 1.00 79.96  ? 547 PRO A N   1 
ATOM   3884 C  CA  . PRO A 1 547 ? 154.125 182.071 197.494 1.00 79.96  ? 547 PRO A CA  1 
ATOM   3885 C  C   . PRO A 1 547 ? 154.602 182.993 196.383 1.00 79.96  ? 547 PRO A C   1 
ATOM   3886 O  O   . PRO A 1 547 ? 155.109 182.557 195.347 1.00 79.96  ? 547 PRO A O   1 
ATOM   3887 C  CB  . PRO A 1 547 ? 155.200 181.906 198.574 1.00 79.96  ? 547 PRO A CB  1 
ATOM   3888 C  CG  . PRO A 1 547 ? 155.150 180.464 198.949 1.00 79.96  ? 547 PRO A CG  1 
ATOM   3889 C  CD  . PRO A 1 547 ? 154.777 179.736 197.700 1.00 79.96  ? 547 PRO A CD  1 
ATOM   3890 N  N   . ALA A 1 548 ? 154.414 184.295 196.616 1.00 81.56  ? 548 ALA A N   1 
ATOM   3891 C  CA  . ALA A 1 548 ? 154.732 185.294 195.602 1.00 81.56  ? 548 ALA A CA  1 
ATOM   3892 C  C   . ALA A 1 548 ? 156.223 185.346 195.292 1.00 81.56  ? 548 ALA A C   1 
ATOM   3893 O  O   . ALA A 1 548 ? 156.604 185.591 194.143 1.00 81.56  ? 548 ALA A O   1 
ATOM   3894 C  CB  . ALA A 1 548 ? 154.238 186.669 196.049 1.00 81.56  ? 548 ALA A CB  1 
ATOM   3895 N  N   . TRP A 1 549 ? 157.079 185.114 196.288 1.00 82.59  ? 549 TRP A N   1 
ATOM   3896 C  CA  . TRP A 1 549 ? 158.513 185.145 196.026 1.00 82.59  ? 549 TRP A CA  1 
ATOM   3897 C  C   . TRP A 1 549 ? 158.975 183.896 195.284 1.00 82.59  ? 549 TRP A C   1 
ATOM   3898 O  O   . TRP A 1 549 ? 159.978 183.943 194.563 1.00 82.59  ? 549 TRP A O   1 
ATOM   3899 C  CB  . TRP A 1 549 ? 159.282 185.333 197.333 1.00 82.59  ? 549 TRP A CB  1 
ATOM   3900 C  CG  . TRP A 1 549 ? 159.192 184.190 198.286 1.00 82.59  ? 549 TRP A CG  1 
ATOM   3901 C  CD1 . TRP A 1 549 ? 158.262 184.015 199.266 1.00 82.59  ? 549 TRP A CD1 1 
ATOM   3902 C  CD2 . TRP A 1 549 ? 160.103 183.092 198.395 1.00 82.59  ? 549 TRP A CD2 1 
ATOM   3903 N  NE1 . TRP A 1 549 ? 158.516 182.856 199.957 1.00 82.59  ? 549 TRP A NE1 1 
ATOM   3904 C  CE2 . TRP A 1 549 ? 159.645 182.273 199.444 1.00 82.59  ? 549 TRP A CE2 1 
ATOM   3905 C  CE3 . TRP A 1 549 ? 161.254 182.713 197.699 1.00 82.59  ? 549 TRP A CE3 1 
ATOM   3906 C  CZ2 . TRP A 1 549 ? 160.296 181.101 199.814 1.00 82.59  ? 549 TRP A CZ2 1 
ATOM   3907 C  CZ3 . TRP A 1 549 ? 161.899 181.548 198.067 1.00 82.59  ? 549 TRP A CZ3 1 
ATOM   3908 C  CH2 . TRP A 1 549 ? 161.419 180.757 199.115 1.00 82.59  ? 549 TRP A CH2 1 
ATOM   3909 N  N   . GLY A 1 550 ? 158.252 182.783 195.424 1.00 82.62  ? 550 GLY A N   1 
ATOM   3910 C  CA  . GLY A 1 550 ? 158.546 181.617 194.606 1.00 82.62  ? 550 GLY A CA  1 
ATOM   3911 C  C   . GLY A 1 550 ? 158.259 181.853 193.135 1.00 82.62  ? 550 GLY A C   1 
ATOM   3912 O  O   . GLY A 1 550 ? 159.070 181.507 192.269 1.00 82.62  ? 550 GLY A O   1 
ATOM   3913 N  N   . TYR A 1 551 ? 157.109 182.460 192.832 1.00 83.57  ? 551 TYR A N   1 
ATOM   3914 C  CA  . TYR A 1 551 ? 156.828 182.869 191.460 1.00 83.57  ? 551 TYR A CA  1 
ATOM   3915 C  C   . TYR A 1 551 ? 157.824 183.917 190.991 1.00 83.57  ? 551 TYR A C   1 
ATOM   3916 O  O   . TYR A 1 551 ? 158.200 183.942 189.815 1.00 83.57  ? 551 TYR A O   1 
ATOM   3917 C  CB  . TYR A 1 551 ? 155.407 183.413 191.351 1.00 83.57  ? 551 TYR A CB  1 
ATOM   3918 C  CG  . TYR A 1 551 ? 154.348 182.350 191.380 1.00 83.57  ? 551 TYR A CG  1 
ATOM   3919 C  CD1 . TYR A 1 551 ? 154.596 181.086 190.869 1.00 83.57  ? 551 TYR A CD1 1 
ATOM   3920 C  CD2 . TYR A 1 551 ? 153.101 182.608 191.927 1.00 83.57  ? 551 TYR A CD2 1 
ATOM   3921 C  CE1 . TYR A 1 551 ? 153.627 180.108 190.895 1.00 83.57  ? 551 TYR A CE1 1 
ATOM   3922 C  CE2 . TYR A 1 551 ? 152.128 181.639 191.961 1.00 83.57  ? 551 TYR A CE2 1 
ATOM   3923 C  CZ  . TYR A 1 551 ? 152.395 180.393 191.442 1.00 83.57  ? 551 TYR A CZ  1 
ATOM   3924 O  OH  . TYR A 1 551 ? 151.424 179.426 191.484 1.00 83.57  ? 551 TYR A OH  1 
ATOM   3925 N  N   . GLY A 1 552 ? 158.262 184.787 191.904 1.00 84.86  ? 552 GLY A N   1 
ATOM   3926 C  CA  . GLY A 1 552 ? 159.258 185.783 191.553 1.00 84.86  ? 552 GLY A CA  1 
ATOM   3927 C  C   . GLY A 1 552 ? 160.579 185.172 191.131 1.00 84.86  ? 552 GLY A C   1 
ATOM   3928 O  O   . GLY A 1 552 ? 161.144 185.554 190.108 1.00 84.86  ? 552 GLY A O   1 
ATOM   3929 N  N   . ILE A 1 553 ? 161.073 184.192 191.893 1.00 81.08  ? 553 ILE A N   1 
ATOM   3930 C  CA  . ILE A 1 553 ? 162.347 183.574 191.530 1.00 81.08  ? 553 ILE A CA  1 
ATOM   3931 C  C   . ILE A 1 553 ? 162.189 182.685 190.298 1.00 81.08  ? 553 ILE A C   1 
ATOM   3932 O  O   . ILE A 1 553 ? 163.106 182.607 189.464 1.00 81.08  ? 553 ILE A O   1 
ATOM   3933 C  CB  . ILE A 1 553 ? 162.968 182.825 192.733 1.00 81.08  ? 553 ILE A CB  1 
ATOM   3934 C  CG1 . ILE A 1 553 ? 164.413 182.419 192.432 1.00 81.08  ? 553 ILE A CG1 1 
ATOM   3935 C  CG2 . ILE A 1 553 ? 162.160 181.608 193.147 1.00 81.08  ? 553 ILE A CG2 1 
ATOM   3936 C  CD1 . ILE A 1 553 ? 165.188 181.977 193.653 1.00 81.08  ? 553 ILE A CD1 1 
ATOM   3937 N  N   . GLY A 1 554 ? 161.026 182.046 190.127 1.00 77.37  ? 554 GLY A N   1 
ATOM   3938 C  CA  . GLY A 1 554 ? 160.799 181.259 188.924 1.00 77.37  ? 554 GLY A CA  1 
ATOM   3939 C  C   . GLY A 1 554 ? 160.778 182.109 187.668 1.00 77.37  ? 554 GLY A C   1 
ATOM   3940 O  O   . GLY A 1 554 ? 161.443 181.794 186.676 1.00 77.37  ? 554 GLY A O   1 
ATOM   3941 N  N   . TRP A 1 555 ? 160.042 183.224 187.708 1.00 79.79  ? 555 TRP A N   1 
ATOM   3942 C  CA  . TRP A 1 555 ? 160.025 184.146 186.579 1.00 79.79  ? 555 TRP A CA  1 
ATOM   3943 C  C   . TRP A 1 555 ? 161.373 184.821 186.388 1.00 79.79  ? 555 TRP A C   1 
ATOM   3944 O  O   . TRP A 1 555 ? 161.748 185.124 185.253 1.00 79.79  ? 555 TRP A O   1 
ATOM   3945 C  CB  . TRP A 1 555 ? 158.935 185.199 186.770 1.00 79.79  ? 555 TRP A CB  1 
ATOM   3946 C  CG  . TRP A 1 555 ? 157.626 184.824 186.160 1.00 79.79  ? 555 TRP A CG  1 
ATOM   3947 C  CD1 . TRP A 1 555 ? 156.466 184.549 186.819 1.00 79.79  ? 555 TRP A CD1 1 
ATOM   3948 C  CD2 . TRP A 1 555 ? 157.338 184.686 184.764 1.00 79.79  ? 555 TRP A CD2 1 
ATOM   3949 N  NE1 . TRP A 1 555 ? 155.473 184.245 185.921 1.00 79.79  ? 555 TRP A NE1 1 
ATOM   3950 C  CE2 . TRP A 1 555 ? 155.983 184.322 184.652 1.00 79.79  ? 555 TRP A CE2 1 
ATOM   3951 C  CE3 . TRP A 1 555 ? 158.095 184.833 183.597 1.00 79.79  ? 555 TRP A CE3 1 
ATOM   3952 C  CZ2 . TRP A 1 555 ? 155.369 184.103 183.422 1.00 79.79  ? 555 TRP A CZ2 1 
ATOM   3953 C  CZ3 . TRP A 1 555 ? 157.483 184.615 182.378 1.00 79.79  ? 555 TRP A CZ3 1 
ATOM   3954 C  CH2 . TRP A 1 555 ? 156.135 184.255 182.299 1.00 79.79  ? 555 TRP A CH2 1 
ATOM   3955 N  N   . LEU A 1 556 ? 162.117 185.046 187.474 1.00 81.67  ? 556 LEU A N   1 
ATOM   3956 C  CA  . LEU A 1 556 ? 163.437 185.655 187.370 1.00 81.67  ? 556 LEU A CA  1 
ATOM   3957 C  C   . LEU A 1 556 ? 164.393 184.754 186.605 1.00 81.67  ? 556 LEU A C   1 
ATOM   3958 O  O   . LEU A 1 556 ? 165.095 185.208 185.695 1.00 81.67  ? 556 LEU A O   1 
ATOM   3959 C  CB  . LEU A 1 556 ? 163.975 185.962 188.770 1.00 81.67  ? 556 LEU A CB  1 
ATOM   3960 C  CG  . LEU A 1 556 ? 165.238 186.810 188.928 1.00 81.67  ? 556 LEU A CG  1 
ATOM   3961 C  CD1 . LEU A 1 556 ? 165.090 187.731 190.124 1.00 81.67  ? 556 LEU A CD1 1 
ATOM   3962 C  CD2 . LEU A 1 556 ? 166.468 185.931 189.104 1.00 81.67  ? 556 LEU A CD2 1 
ATOM   3963 N  N   . MET A 1 557 ? 164.416 183.464 186.937 1.00 76.51  ? 557 MET A N   1 
ATOM   3964 C  CA  . MET A 1 557 ? 165.334 182.590 186.220 1.00 76.51  ? 557 MET A CA  1 
ATOM   3965 C  C   . MET A 1 557 ? 164.823 182.251 184.822 1.00 76.51  ? 557 MET A C   1 
ATOM   3966 O  O   . MET A 1 557 ? 165.632 182.024 183.912 1.00 76.51  ? 557 MET A O   1 
ATOM   3967 C  CB  . MET A 1 557 ? 165.613 181.324 187.027 1.00 76.51  ? 557 MET A CB  1 
ATOM   3968 C  CG  . MET A 1 557 ? 164.425 180.450 187.337 1.00 76.51  ? 557 MET A CG  1 
ATOM   3969 S  SD  . MET A 1 557 ? 164.420 179.105 186.153 1.00 76.51  ? 557 MET A SD  1 
ATOM   3970 C  CE  . MET A 1 557 ? 165.970 178.339 186.617 1.00 76.51  ? 557 MET A CE  1 
ATOM   3971 N  N   . ALA A 1 558 ? 163.499 182.234 184.620 1.00 76.59  ? 558 ALA A N   1 
ATOM   3972 C  CA  . ALA A 1 558 ? 162.963 182.055 183.274 1.00 76.59  ? 558 ALA A CA  1 
ATOM   3973 C  C   . ALA A 1 558 ? 163.311 183.234 182.376 1.00 76.59  ? 558 ALA A C   1 
ATOM   3974 O  O   . ALA A 1 558 ? 163.610 183.049 181.191 1.00 76.59  ? 558 ALA A O   1 
ATOM   3975 C  CB  . ALA A 1 558 ? 161.450 181.855 183.330 1.00 76.59  ? 558 ALA A CB  1 
ATOM   3976 N  N   . LEU A 1 559 ? 163.258 184.454 182.916 1.00 79.29  ? 559 LEU A N   1 
ATOM   3977 C  CA  . LEU A 1 559 ? 163.701 185.625 182.171 1.00 79.29  ? 559 LEU A CA  1 
ATOM   3978 C  C   . LEU A 1 559 ? 165.197 185.567 181.905 1.00 79.29  ? 559 LEU A C   1 
ATOM   3979 O  O   . LEU A 1 559 ? 165.644 185.816 180.781 1.00 79.29  ? 559 LEU A O   1 
ATOM   3980 C  CB  . LEU A 1 559 ? 163.342 186.899 182.935 1.00 79.29  ? 559 LEU A CB  1 
ATOM   3981 C  CG  . LEU A 1 559 ? 161.911 187.412 182.787 1.00 79.29  ? 559 LEU A CG  1 
ATOM   3982 C  CD1 . LEU A 1 559 ? 161.635 188.499 183.808 1.00 79.29  ? 559 LEU A CD1 1 
ATOM   3983 C  CD2 . LEU A 1 559 ? 161.673 187.927 181.382 1.00 79.29  ? 559 LEU A CD2 1 
ATOM   3984 N  N   . SER A 1 560 ? 165.984 185.207 182.925 1.00 79.80  ? 560 SER A N   1 
ATOM   3985 C  CA  . SER A 1 560 ? 167.433 185.116 182.777 1.00 79.80  ? 560 SER A CA  1 
ATOM   3986 C  C   . SER A 1 560 ? 167.853 184.043 181.785 1.00 79.80  ? 560 SER A C   1 
ATOM   3987 O  O   . SER A 1 560 ? 168.971 184.099 181.264 1.00 79.80  ? 560 SER A O   1 
ATOM   3988 C  CB  . SER A 1 560 ? 168.081 184.843 184.133 1.00 79.80  ? 560 SER A CB  1 
ATOM   3989 O  OG  . SER A 1 560 ? 169.476 184.638 183.997 1.00 79.80  ? 560 SER A OG  1 
ATOM   3990 N  N   . SER A 1 561 ? 166.992 183.063 181.521 1.00 80.94  ? 561 SER A N   1 
ATOM   3991 C  CA  . SER A 1 561 ? 167.281 182.101 180.468 1.00 80.94  ? 561 SER A CA  1 
ATOM   3992 C  C   . SER A 1 561 ? 166.980 182.644 179.075 1.00 80.94  ? 561 SER A C   1 
ATOM   3993 O  O   . SER A 1 561 ? 167.530 182.139 178.092 1.00 80.94  ? 561 SER A O   1 
ATOM   3994 C  CB  . SER A 1 561 ? 166.491 180.818 180.709 1.00 80.94  ? 561 SER A CB  1 
ATOM   3995 O  OG  . SER A 1 561 ? 166.553 179.970 179.581 1.00 80.94  ? 561 SER A OG  1 
ATOM   3996 N  N   . MET A 1 562 ? 166.124 183.661 178.960 1.00 79.67  ? 562 MET A N   1 
ATOM   3997 C  CA  . MET A 1 562 ? 165.671 184.124 177.656 1.00 79.67  ? 562 MET A CA  1 
ATOM   3998 C  C   . MET A 1 562 ? 165.832 185.620 177.421 1.00 79.67  ? 562 MET A C   1 
ATOM   3999 O  O   . MET A 1 562 ? 165.490 186.091 176.331 1.00 79.67  ? 562 MET A O   1 
ATOM   4000 C  CB  . MET A 1 562 ? 164.204 183.730 177.435 1.00 79.67  ? 562 MET A CB  1 
ATOM   4001 C  CG  . MET A 1 562 ? 163.187 184.627 178.116 1.00 79.67  ? 562 MET A CG  1 
ATOM   4002 S  SD  . MET A 1 562 ? 161.643 183.750 178.423 1.00 79.67  ? 562 MET A SD  1 
ATOM   4003 C  CE  . MET A 1 562 ? 160.684 185.019 179.240 1.00 79.67  ? 562 MET A CE  1 
ATOM   4004 N  N   . LEU A 1 563 ? 166.343 186.384 178.387 1.00 83.29  ? 563 LEU A N   1 
ATOM   4005 C  CA  . LEU A 1 563 ? 166.660 187.779 178.102 1.00 83.29  ? 563 LEU A CA  1 
ATOM   4006 C  C   . LEU A 1 563 ? 168.046 187.943 177.502 1.00 83.29  ? 563 LEU A C   1 
ATOM   4007 O  O   . LEU A 1 563 ? 168.460 189.076 177.242 1.00 83.29  ? 563 LEU A O   1 
ATOM   4008 C  CB  . LEU A 1 563 ? 166.531 188.650 179.362 1.00 83.29  ? 563 LEU A CB  1 
ATOM   4009 C  CG  . LEU A 1 563 ? 167.425 188.509 180.603 1.00 83.29  ? 563 LEU A CG  1 
ATOM   4010 C  CD1 . LEU A 1 563 ? 168.695 189.354 180.546 1.00 83.29  ? 563 LEU A CD1 1 
ATOM   4011 C  CD2 . LEU A 1 563 ? 166.625 188.852 181.848 1.00 83.29  ? 563 LEU A CD2 1 
ATOM   4012 N  N   . CYS A 1 564 ? 168.772 186.846 177.285 1.00 87.45  ? 564 CYS A N   1 
ATOM   4013 C  CA  . CYS A 1 564 ? 170.127 186.950 176.767 1.00 87.45  ? 564 CYS A CA  1 
ATOM   4014 C  C   . CYS A 1 564 ? 170.154 187.250 175.275 1.00 87.45  ? 564 CYS A C   1 
ATOM   4015 O  O   . CYS A 1 564 ? 171.205 187.638 174.756 1.00 87.45  ? 564 CYS A O   1 
ATOM   4016 C  CB  . CYS A 1 564 ? 170.898 185.664 177.061 1.00 87.45  ? 564 CYS A CB  1 
ATOM   4017 S  SG  . CYS A 1 564 ? 172.687 185.879 177.100 1.00 87.45  ? 564 CYS A SG  1 
ATOM   4018 N  N   . ILE A 1 565 ? 169.036 187.083 174.577 1.00 88.84  ? 565 ILE A N   1 
ATOM   4019 C  CA  . ILE A 1 565 ? 168.962 187.443 173.162 1.00 88.84  ? 565 ILE A CA  1 
ATOM   4020 C  C   . ILE A 1 565 ? 168.826 188.959 172.986 1.00 88.84  ? 565 ILE A C   1 
ATOM   4021 O  O   . ILE A 1 565 ? 169.649 189.535 172.254 1.00 88.84  ? 565 ILE A O   1 
ATOM   4022 C  CB  . ILE A 1 565 ? 167.837 186.678 172.439 1.00 88.84  ? 565 ILE A CB  1 
ATOM   4023 C  CG1 . ILE A 1 565 ? 167.925 185.182 172.737 1.00 88.84  ? 565 ILE A CG1 1 
ATOM   4024 C  CG2 . ILE A 1 565 ? 167.905 186.932 170.950 1.00 88.84  ? 565 ILE A CG2 1 
ATOM   4025 C  CD1 . ILE A 1 565 ? 166.759 184.393 172.201 1.00 88.84  ? 565 ILE A CD1 1 
ATOM   4026 N  N   . PRO A 1 566 ? 167.850 189.666 173.595 1.00 92.22  ? 566 PRO A N   1 
ATOM   4027 C  CA  . PRO A 1 566 ? 167.826 191.125 173.396 1.00 92.22  ? 566 PRO A CA  1 
ATOM   4028 C  C   . PRO A 1 566 ? 168.997 191.837 174.046 1.00 92.22  ? 566 PRO A C   1 
ATOM   4029 O  O   . PRO A 1 566 ? 169.421 192.884 173.542 1.00 92.22  ? 566 PRO A O   1 
ATOM   4030 C  CB  . PRO A 1 566 ? 166.488 191.554 174.019 1.00 92.22  ? 566 PRO A CB  1 
ATOM   4031 C  CG  . PRO A 1 566 ? 165.715 190.310 174.194 1.00 92.22  ? 566 PRO A CG  1 
ATOM   4032 C  CD  . PRO A 1 566 ? 166.735 189.278 174.482 1.00 92.22  ? 566 PRO A CD  1 
ATOM   4033 N  N   . LEU A 1 567 ? 169.538 191.295 175.139 1.00 93.35  ? 567 LEU A N   1 
ATOM   4034 C  CA  . LEU A 1 567 ? 170.734 191.875 175.740 1.00 93.35  ? 567 LEU A CA  1 
ATOM   4035 C  C   . LEU A 1 567 ? 171.921 191.789 174.789 1.00 93.35  ? 567 LEU A C   1 
ATOM   4036 O  O   . LEU A 1 567 ? 172.671 192.763 174.631 1.00 93.35  ? 567 LEU A O   1 
ATOM   4037 C  CB  . LEU A 1 567 ? 171.045 191.174 177.062 1.00 93.35  ? 567 LEU A CB  1 
ATOM   4038 C  CG  . LEU A 1 567 ? 172.085 191.802 177.991 1.00 93.35  ? 567 LEU A CG  1 
ATOM   4039 C  CD1 . LEU A 1 567 ? 171.608 191.719 179.428 1.00 93.35  ? 567 LEU A CD1 1 
ATOM   4040 C  CD2 . LEU A 1 567 ? 173.436 191.115 177.847 1.00 93.35  ? 567 LEU A CD2 1 
ATOM   4041 N  N   . TRP A 1 568 ? 172.097 190.638 174.132 1.00 99.23  ? 568 TRP A N   1 
ATOM   4042 C  CA  . TRP A 1 568 ? 173.191 190.513 173.178 1.00 99.23  ? 568 TRP A CA  1 
ATOM   4043 C  C   . TRP A 1 568 ? 172.957 191.377 171.949 1.00 99.23  ? 568 TRP A C   1 
ATOM   4044 O  O   . TRP A 1 568 ? 173.916 191.927 171.398 1.00 99.23  ? 568 TRP A O   1 
ATOM   4045 C  CB  . TRP A 1 568 ? 173.406 189.059 172.766 1.00 99.23  ? 568 TRP A CB  1 
ATOM   4046 C  CG  . TRP A 1 568 ? 174.593 188.905 171.865 1.00 99.23  ? 568 TRP A CG  1 
ATOM   4047 C  CD1 . TRP A 1 568 ? 174.602 188.953 170.502 1.00 99.23  ? 568 TRP A CD1 1 
ATOM   4048 C  CD2 . TRP A 1 568 ? 175.955 188.722 172.268 1.00 99.23  ? 568 TRP A CD2 1 
ATOM   4049 N  NE1 . TRP A 1 568 ? 175.882 188.798 170.031 1.00 99.23  ? 568 TRP A NE1 1 
ATOM   4050 C  CE2 . TRP A 1 568 ? 176.731 188.649 171.095 1.00 99.23  ? 568 TRP A CE2 1 
ATOM   4051 C  CE3 . TRP A 1 568 ? 176.591 188.599 173.506 1.00 99.23  ? 568 TRP A CE3 1 
ATOM   4052 C  CZ2 . TRP A 1 568 ? 178.111 188.462 171.123 1.00 99.23  ? 568 TRP A CZ2 1 
ATOM   4053 C  CZ3 . TRP A 1 568 ? 177.962 188.417 173.531 1.00 99.23  ? 568 TRP A CZ3 1 
ATOM   4054 C  CH2 . TRP A 1 568 ? 178.706 188.348 172.348 1.00 99.23  ? 568 TRP A CH2 1 
ATOM   4055 N  N   . ILE A 1 569 ? 171.699 191.519 171.519 1.00 96.86  ? 569 ILE A N   1 
ATOM   4056 C  CA  . ILE A 1 569 ? 171.380 192.424 170.416 1.00 96.86  ? 569 ILE A CA  1 
ATOM   4057 C  C   . ILE A 1 569 ? 171.763 193.855 170.775 1.00 96.86  ? 569 ILE A C   1 
ATOM   4058 O  O   . ILE A 1 569 ? 172.392 194.567 169.978 1.00 96.86  ? 569 ILE A O   1 
ATOM   4059 C  CB  . ILE A 1 569 ? 169.886 192.309 170.054 1.00 96.86  ? 569 ILE A CB  1 
ATOM   4060 C  CG1 . ILE A 1 569 ? 169.619 191.012 169.293 1.00 96.86  ? 569 ILE A CG1 1 
ATOM   4061 C  CG2 . ILE A 1 569 ? 169.422 193.505 169.239 1.00 96.86  ? 569 ILE A CG2 1 
ATOM   4062 C  CD1 . ILE A 1 569 ? 168.196 190.525 169.418 1.00 96.86  ? 569 ILE A CD1 1 
ATOM   4063 N  N   . CYS A 1 570 ? 171.426 194.281 171.997 1.00 102.28 ? 570 CYS A N   1 
ATOM   4064 C  CA  . CYS A 1 570 ? 171.737 195.636 172.439 1.00 102.28 ? 570 CYS A CA  1 
ATOM   4065 C  C   . CYS A 1 570 ? 173.240 195.873 172.530 1.00 102.28 ? 570 CYS A C   1 
ATOM   4066 O  O   . CYS A 1 570 ? 173.729 196.922 172.096 1.00 102.28 ? 570 CYS A O   1 
ATOM   4067 C  CB  . CYS A 1 570 ? 171.072 195.913 173.786 1.00 102.28 ? 570 CYS A CB  1 
ATOM   4068 S  SG  . CYS A 1 570 ? 169.323 196.354 173.678 1.00 102.28 ? 570 CYS A SG  1 
ATOM   4069 N  N   . ILE A 1 571 ? 173.996 194.913 173.072 1.00 106.00 ? 571 ILE A N   1 
ATOM   4070 C  CA  . ILE A 1 571 ? 175.426 195.181 173.214 1.00 106.00 ? 571 ILE A CA  1 
ATOM   4071 C  C   . ILE A 1 571 ? 176.140 195.032 171.875 1.00 106.00 ? 571 ILE A C   1 
ATOM   4072 O  O   . ILE A 1 571 ? 177.191 195.646 171.661 1.00 106.00 ? 571 ILE A O   1 
ATOM   4073 C  CB  . ILE A 1 571 ? 176.083 194.299 174.291 1.00 106.00 ? 571 ILE A CB  1 
ATOM   4074 C  CG1 . ILE A 1 571 ? 175.837 192.820 174.027 1.00 106.00 ? 571 ILE A CG1 1 
ATOM   4075 C  CG2 . ILE A 1 571 ? 175.571 194.680 175.670 1.00 106.00 ? 571 ILE A CG2 1 
ATOM   4076 C  CD1 . ILE A 1 571 ? 176.664 191.912 174.905 1.00 106.00 ? 571 ILE A CD1 1 
ATOM   4077 N  N   . THR A 1 572 ? 175.593 194.238 170.950 1.00 107.94 ? 572 THR A N   1 
ATOM   4078 C  CA  . THR A 1 572 ? 176.171 194.177 169.611 1.00 107.94 ? 572 THR A CA  1 
ATOM   4079 C  C   . THR A 1 572 ? 175.914 195.468 168.847 1.00 107.94 ? 572 THR A C   1 
ATOM   4080 O  O   . THR A 1 572 ? 176.769 195.920 168.077 1.00 107.94 ? 572 THR A O   1 
ATOM   4081 C  CB  . THR A 1 572 ? 175.609 192.980 168.845 1.00 107.94 ? 572 THR A CB  1 
ATOM   4082 O  OG1 . THR A 1 572 ? 175.536 191.846 169.716 1.00 107.94 ? 572 THR A OG1 1 
ATOM   4083 C  CG2 . THR A 1 572 ? 176.501 192.640 167.662 1.00 107.94 ? 572 THR A CG2 1 
ATOM   4084 N  N   . VAL A 1 573 ? 174.737 196.068 169.040 1.00 110.75 ? 573 VAL A N   1 
ATOM   4085 C  CA  . VAL A 1 573 ? 174.456 197.368 168.437 1.00 110.75 ? 573 VAL A CA  1 
ATOM   4086 C  C   . VAL A 1 573 ? 175.356 198.442 169.041 1.00 110.75 ? 573 VAL A C   1 
ATOM   4087 O  O   . VAL A 1 573 ? 175.917 199.278 168.321 1.00 110.75 ? 573 VAL A O   1 
ATOM   4088 C  CB  . VAL A 1 573 ? 172.961 197.706 168.593 1.00 110.75 ? 573 VAL A CB  1 
ATOM   4089 C  CG1 . VAL A 1 573 ? 172.705 199.194 168.400 1.00 110.75 ? 573 VAL A CG1 1 
ATOM   4090 C  CG2 . VAL A 1 573 ? 172.134 196.895 167.608 1.00 110.75 ? 573 VAL A CG2 1 
ATOM   4091 N  N   . TRP A 1 574 ? 175.534 198.417 170.365 1.00 119.30 ? 574 TRP A N   1 
ATOM   4092 C  CA  . TRP A 1 574 ? 176.340 199.438 171.030 1.00 119.30 ? 574 TRP A CA  1 
ATOM   4093 C  C   . TRP A 1 574 ? 177.825 199.300 170.712 1.00 119.30 ? 574 TRP A C   1 
ATOM   4094 O  O   . TRP A 1 574 ? 178.524 200.312 170.591 1.00 119.30 ? 574 TRP A O   1 
ATOM   4095 C  CB  . TRP A 1 574 ? 176.111 199.376 172.543 1.00 119.30 ? 574 TRP A CB  1 
ATOM   4096 C  CG  . TRP A 1 574 ? 177.165 200.071 173.362 1.00 119.30 ? 574 TRP A CG  1 
ATOM   4097 C  CD1 . TRP A 1 574 ? 177.189 201.389 173.716 1.00 119.30 ? 574 TRP A CD1 1 
ATOM   4098 C  CD2 . TRP A 1 574 ? 178.338 199.481 173.939 1.00 119.30 ? 574 TRP A CD2 1 
ATOM   4099 N  NE1 . TRP A 1 574 ? 178.306 201.657 174.470 1.00 119.30 ? 574 TRP A NE1 1 
ATOM   4100 C  CE2 . TRP A 1 574 ? 179.029 200.503 174.620 1.00 119.30 ? 574 TRP A CE2 1 
ATOM   4101 C  CE3 . TRP A 1 574 ? 178.876 198.190 173.938 1.00 119.30 ? 574 TRP A CE3 1 
ATOM   4102 C  CZ2 . TRP A 1 574 ? 180.225 200.274 175.296 1.00 119.30 ? 574 TRP A CZ2 1 
ATOM   4103 C  CZ3 . TRP A 1 574 ? 180.064 197.964 174.610 1.00 119.30 ? 574 TRP A CZ3 1 
ATOM   4104 C  CH2 . TRP A 1 574 ? 180.725 199.001 175.279 1.00 119.30 ? 574 TRP A CH2 1 
ATOM   4105 N  N   . LYS A 1 575 ? 178.325 198.068 170.577 1.00 120.62 ? 575 LYS A N   1 
ATOM   4106 C  CA  . LYS A 1 575 ? 179.760 197.859 170.402 1.00 120.62 ? 575 LYS A CA  1 
ATOM   4107 C  C   . LYS A 1 575 ? 180.229 198.321 169.027 1.00 120.62 ? 575 LYS A C   1 
ATOM   4108 O  O   . LYS A 1 575 ? 181.253 199.003 168.907 1.00 120.62 ? 575 LYS A O   1 
ATOM   4109 C  CB  . LYS A 1 575 ? 180.103 196.385 170.621 1.00 120.62 ? 575 LYS A CB  1 
ATOM   4110 C  CG  . LYS A 1 575 ? 181.596 196.087 170.634 1.00 120.62 ? 575 LYS A CG  1 
ATOM   4111 C  CD  . LYS A 1 575 ? 182.341 197.009 171.590 1.00 120.62 ? 575 LYS A CD  1 
ATOM   4112 C  CE  . LYS A 1 575 ? 183.767 196.533 171.822 1.00 120.62 ? 575 LYS A CE  1 
ATOM   4113 N  NZ  . LYS A 1 575 ? 184.656 197.639 172.273 1.00 120.62 ? 575 LYS A NZ  1 
ATOM   4114 N  N   . THR A 1 576 ? 179.499 197.954 167.979 1.00 122.75 ? 576 THR A N   1 
ATOM   4115 C  CA  . THR A 1 576 ? 179.831 198.337 166.608 1.00 122.75 ? 576 THR A CA  1 
ATOM   4116 C  C   . THR A 1 576 ? 178.692 199.203 166.081 1.00 122.75 ? 576 THR A C   1 
ATOM   4117 O  O   . THR A 1 576 ? 177.663 198.683 165.639 1.00 122.75 ? 576 THR A O   1 
ATOM   4118 C  CB  . THR A 1 576 ? 180.050 197.110 165.729 1.00 122.75 ? 576 THR A CB  1 
ATOM   4119 O  OG1 . THR A 1 576 ? 178.842 196.340 165.673 1.00 122.75 ? 576 THR A OG1 1 
ATOM   4120 C  CG2 . THR A 1 576 ? 181.170 196.244 166.289 1.00 122.75 ? 576 THR A CG2 1 
ATOM   4121 N  N   . GLU A 1 577 ? 178.878 200.520 166.121 1.00 128.50 ? 577 GLU A N   1 
ATOM   4122 C  CA  . GLU A 1 577 ? 177.850 201.468 165.714 1.00 128.50 ? 577 GLU A CA  1 
ATOM   4123 C  C   . GLU A 1 577 ? 178.293 202.217 164.464 1.00 128.50 ? 577 GLU A C   1 
ATOM   4124 O  O   . GLU A 1 577 ? 179.393 202.778 164.418 1.00 128.50 ? 577 GLU A O   1 
ATOM   4125 C  CB  . GLU A 1 577 ? 177.513 202.437 166.858 1.00 128.50 ? 577 GLU A CB  1 
ATOM   4126 C  CG  . GLU A 1 577 ? 178.700 203.144 167.497 1.00 128.50 ? 577 GLU A CG  1 
ATOM   4127 C  CD  . GLU A 1 577 ? 178.295 204.020 168.665 1.00 128.50 ? 577 GLU A CD  1 
ATOM   4128 O  OE1 . GLU A 1 577 ? 177.091 204.050 168.997 1.00 128.50 ? 577 GLU A OE1 1 
ATOM   4129 O  OE2 . GLU A 1 577 ? 179.179 204.680 169.250 1.00 128.50 ? 577 GLU A OE2 1 
ATOM   4130 N  N   . GLY A 1 578 ? 177.446 202.182 163.439 1.00 131.02 ? 578 GLY A N   1 
ATOM   4131 C  CA  . GLY A 1 578 ? 177.670 202.911 162.207 1.00 131.02 ? 578 GLY A CA  1 
ATOM   4132 C  C   . GLY A 1 578 ? 176.386 203.527 161.691 1.00 131.02 ? 578 GLY A C   1 
ATOM   4133 O  O   . GLY A 1 578 ? 176.177 203.592 160.476 1.00 131.02 ? 578 GLY A O   1 
ATOM   4134 N  N   . THR A 1 579 ? 175.522 203.954 162.626 1.00 131.29 ? 579 THR A N   1 
ATOM   4135 C  CA  . THR A 1 579 ? 174.119 204.356 162.452 1.00 131.29 ? 579 THR A CA  1 
ATOM   4136 C  C   . THR A 1 579 ? 173.243 203.175 162.039 1.00 131.29 ? 579 THR A C   1 
ATOM   4137 O  O   . THR A 1 579 ? 173.748 202.137 161.601 1.00 131.29 ? 579 THR A O   1 
ATOM   4138 C  CB  . THR A 1 579 ? 173.948 205.520 161.460 1.00 131.29 ? 579 THR A CB  1 
ATOM   4139 O  OG1 . THR A 1 579 ? 174.234 205.074 160.128 1.00 131.29 ? 579 THR A OG1 1 
ATOM   4140 C  CG2 . THR A 1 579 ? 174.867 206.682 161.823 1.00 131.29 ? 579 THR A CG2 1 
ATOM   4141 N  N   . LEU A 1 580 ? 171.924 203.344 162.173 1.00 130.19 ? 580 LEU A N   1 
ATOM   4142 C  CA  . LEU A 1 580 ? 170.994 202.212 162.158 1.00 130.19 ? 580 LEU A CA  1 
ATOM   4143 C  C   . LEU A 1 580 ? 170.973 201.394 160.863 1.00 130.19 ? 580 LEU A C   1 
ATOM   4144 O  O   . LEU A 1 580 ? 171.055 200.155 160.958 1.00 130.19 ? 580 LEU A O   1 
ATOM   4145 C  CB  . LEU A 1 580 ? 169.589 202.711 162.522 1.00 130.19 ? 580 LEU A CB  1 
ATOM   4146 C  CG  . LEU A 1 580 ? 168.485 201.657 162.608 1.00 130.19 ? 580 LEU A CG  1 
ATOM   4147 C  CD1 . LEU A 1 580 ? 168.793 200.646 163.702 1.00 130.19 ? 580 LEU A CD1 1 
ATOM   4148 C  CD2 . LEU A 1 580 ? 167.133 202.314 162.841 1.00 130.19 ? 580 LEU A CD2 1 
ATOM   4149 N  N   . PRO A 1 581 ? 170.856 201.974 159.652 1.00 127.85 ? 581 PRO A N   1 
ATOM   4150 C  CA  . PRO A 1 581 ? 170.794 201.092 158.470 1.00 127.85 ? 581 PRO A CA  1 
ATOM   4151 C  C   . PRO A 1 581 ? 172.099 200.370 158.187 1.00 127.85 ? 581 PRO A C   1 
ATOM   4152 O  O   . PRO A 1 581 ? 172.075 199.185 157.835 1.00 127.85 ? 581 PRO A O   1 
ATOM   4153 C  CB  . PRO A 1 581 ? 170.405 202.044 157.332 1.00 127.85 ? 581 PRO A CB  1 
ATOM   4154 C  CG  . PRO A 1 581 ? 170.882 203.358 157.760 1.00 127.85 ? 581 PRO A CG  1 
ATOM   4155 C  CD  . PRO A 1 581 ? 170.732 203.392 159.248 1.00 127.85 ? 581 PRO A CD  1 
ATOM   4156 N  N   . GLU A 1 582 ? 173.241 201.038 158.363 1.00 127.73 ? 582 GLU A N   1 
ATOM   4157 C  CA  . GLU A 1 582 ? 174.519 200.356 158.198 1.00 127.73 ? 582 GLU A CA  1 
ATOM   4158 C  C   . GLU A 1 582 ? 174.740 199.310 159.282 1.00 127.73 ? 582 GLU A C   1 
ATOM   4159 O  O   . GLU A 1 582 ? 175.333 198.261 159.009 1.00 127.73 ? 582 GLU A O   1 
ATOM   4160 C  CB  . GLU A 1 582 ? 175.664 201.367 158.189 1.00 127.73 ? 582 GLU A CB  1 
ATOM   4161 N  N   . LYS A 1 583 ? 174.261 199.568 160.504 1.00 126.24 ? 583 LYS A N   1 
ATOM   4162 C  CA  . LYS A 1 583 ? 174.359 198.577 161.574 1.00 126.24 ? 583 LYS A CA  1 
ATOM   4163 C  C   . LYS A 1 583 ? 173.565 197.321 161.240 1.00 126.24 ? 583 LYS A C   1 
ATOM   4164 O  O   . LYS A 1 583 ? 174.071 196.199 161.371 1.00 126.24 ? 583 LYS A O   1 
ATOM   4165 C  CB  . LYS A 1 583 ? 173.872 199.171 162.896 1.00 126.24 ? 583 LYS A CB  1 
ATOM   4166 C  CG  . LYS A 1 583 ? 174.935 199.896 163.701 1.00 126.24 ? 583 LYS A CG  1 
ATOM   4167 C  CD  . LYS A 1 583 ? 174.430 200.202 165.103 1.00 126.24 ? 583 LYS A CD  1 
ATOM   4168 C  CE  . LYS A 1 583 ? 173.784 201.576 165.168 1.00 126.24 ? 583 LYS A CE  1 
ATOM   4169 N  NZ  . LYS A 1 583 ? 174.129 202.300 166.421 1.00 126.24 ? 583 LYS A NZ  1 
ATOM   4170 N  N   . LEU A 1 584 ? 172.315 197.488 160.792 1.00 125.80 ? 584 LEU A N   1 
ATOM   4171 C  CA  . LEU A 1 584 ? 171.513 196.313 160.464 1.00 125.80 ? 584 LEU A CA  1 
ATOM   4172 C  C   . LEU A 1 584 ? 172.034 195.610 159.216 1.00 125.80 ? 584 LEU A C   1 
ATOM   4173 O  O   . LEU A 1 584 ? 171.922 194.383 159.112 1.00 125.80 ? 584 LEU A O   1 
ATOM   4174 C  CB  . LEU A 1 584 ? 170.035 196.693 160.315 1.00 125.80 ? 584 LEU A CB  1 
ATOM   4175 C  CG  . LEU A 1 584 ? 169.512 197.668 159.254 1.00 125.80 ? 584 LEU A CG  1 
ATOM   4176 C  CD1 . LEU A 1 584 ? 169.145 196.976 157.941 1.00 125.80 ? 584 LEU A CD1 1 
ATOM   4177 C  CD2 . LEU A 1 584 ? 168.325 198.450 159.797 1.00 125.80 ? 584 LEU A CD2 1 
ATOM   4178 N  N   . GLN A 1 585 ? 172.623 196.355 158.274 1.00 124.67 ? 585 GLN A N   1 
ATOM   4179 C  CA  . GLN A 1 585 ? 173.205 195.722 157.095 1.00 124.67 ? 585 GLN A CA  1 
ATOM   4180 C  C   . GLN A 1 585 ? 174.452 194.918 157.448 1.00 124.67 ? 585 GLN A C   1 
ATOM   4181 O  O   . GLN A 1 585 ? 174.648 193.813 156.930 1.00 124.67 ? 585 GLN A O   1 
ATOM   4182 C  CB  . GLN A 1 585 ? 173.529 196.777 156.037 1.00 124.67 ? 585 GLN A CB  1 
ATOM   4183 C  CG  . GLN A 1 585 ? 172.325 197.232 155.230 1.00 124.67 ? 585 GLN A CG  1 
ATOM   4184 C  CD  . GLN A 1 585 ? 171.670 196.096 154.473 1.00 124.67 ? 585 GLN A CD  1 
ATOM   4185 O  OE1 . GLN A 1 585 ? 170.572 195.659 154.816 1.00 124.67 ? 585 GLN A OE1 1 
ATOM   4186 N  NE2 . GLN A 1 585 ? 172.343 195.611 153.437 1.00 124.67 ? 585 GLN A NE2 1 
ATOM   4187 N  N   . LYS A 1 586 ? 175.306 195.449 158.325 1.00 123.53 ? 586 LYS A N   1 
ATOM   4188 C  CA  . LYS A 1 586 ? 176.520 194.734 158.697 1.00 123.53 ? 586 LYS A CA  1 
ATOM   4189 C  C   . LYS A 1 586 ? 176.267 193.635 159.719 1.00 123.53 ? 586 LYS A C   1 
ATOM   4190 O  O   . LYS A 1 586 ? 177.132 192.773 159.904 1.00 123.53 ? 586 LYS A O   1 
ATOM   4191 C  CB  . LYS A 1 586 ? 177.569 195.710 159.236 1.00 123.53 ? 586 LYS A CB  1 
ATOM   4192 C  CG  . LYS A 1 586 ? 177.306 196.203 160.648 1.00 123.53 ? 586 LYS A CG  1 
ATOM   4193 C  CD  . LYS A 1 586 ? 178.401 197.147 161.117 1.00 123.53 ? 586 LYS A CD  1 
ATOM   4194 C  CE  . LYS A 1 586 ? 177.981 197.897 162.371 1.00 123.53 ? 586 LYS A CE  1 
ATOM   4195 N  NZ  . LYS A 1 586 ? 177.528 196.974 163.446 1.00 123.53 ? 586 LYS A NZ  1 
ATOM   4196 N  N   . LEU A 1 587 ? 175.111 193.642 160.384 1.00 119.29 ? 587 LEU A N   1 
ATOM   4197 C  CA  . LEU A 1 587 ? 174.779 192.553 161.293 1.00 119.29 ? 587 LEU A CA  1 
ATOM   4198 C  C   . LEU A 1 587 ? 173.936 191.470 160.632 1.00 119.29 ? 587 LEU A C   1 
ATOM   4199 O  O   . LEU A 1 587 ? 173.978 190.313 161.065 1.00 119.29 ? 587 LEU A O   1 
ATOM   4200 C  CB  . LEU A 1 587 ? 174.051 193.099 162.525 1.00 119.29 ? 587 LEU A CB  1 
ATOM   4201 C  CG  . LEU A 1 587 ? 174.920 193.809 163.570 1.00 119.29 ? 587 LEU A CG  1 
ATOM   4202 C  CD1 . LEU A 1 587 ? 174.179 193.936 164.891 1.00 119.29 ? 587 LEU A CD1 1 
ATOM   4203 C  CD2 . LEU A 1 587 ? 176.248 193.091 163.770 1.00 119.29 ? 587 LEU A CD2 1 
ATOM   4204 N  N   . THR A 1 588 ? 173.173 191.819 159.593 1.00 120.76 ? 588 THR A N   1 
ATOM   4205 C  CA  . THR A 1 588 ? 172.394 190.822 158.866 1.00 120.76 ? 588 THR A CA  1 
ATOM   4206 C  C   . THR A 1 588 ? 173.287 189.938 158.001 1.00 120.76 ? 588 THR A C   1 
ATOM   4207 O  O   . THR A 1 588 ? 173.001 188.747 157.826 1.00 120.76 ? 588 THR A O   1 
ATOM   4208 C  CB  . THR A 1 588 ? 171.332 191.528 158.016 1.00 120.76 ? 588 THR A CB  1 
ATOM   4209 O  OG1 . THR A 1 588 ? 170.560 192.401 158.850 1.00 120.76 ? 588 THR A OG1 1 
ATOM   4210 C  CG2 . THR A 1 588 ? 170.392 190.530 157.350 1.00 120.76 ? 588 THR A CG2 1 
ATOM   4211 N  N   . THR A 1 589 ? 174.377 190.494 157.481 1.00 123.08 ? 589 THR A N   1 
ATOM   4212 C  CA  . THR A 1 589 ? 175.232 189.772 156.542 1.00 123.08 ? 589 THR A CA  1 
ATOM   4213 C  C   . THR A 1 589 ? 175.961 188.631 157.244 1.00 123.08 ? 589 THR A C   1 
ATOM   4214 O  O   . THR A 1 589 ? 176.584 188.850 158.290 1.00 123.08 ? 589 THR A O   1 
ATOM   4215 C  CB  . THR A 1 589 ? 176.240 190.730 155.909 1.00 123.08 ? 589 THR A CB  1 
ATOM   4216 O  OG1 . THR A 1 589 ? 175.541 191.773 155.219 1.00 123.08 ? 589 THR A OG1 1 
ATOM   4217 C  CG2 . THR A 1 589 ? 177.139 189.995 154.926 1.00 123.08 ? 589 THR A CG2 1 
ATOM   4218 N  N   . PRO A 1 590 ? 175.904 187.403 156.709 1.00 120.48 ? 590 PRO A N   1 
ATOM   4219 C  CA  . PRO A 1 590 ? 176.627 186.284 157.330 1.00 120.48 ? 590 PRO A CA  1 
ATOM   4220 C  C   . PRO A 1 590 ? 178.135 186.405 157.181 1.00 120.48 ? 590 PRO A C   1 
ATOM   4221 O  O   . PRO A 1 590 ? 178.628 187.246 156.423 1.00 120.48 ? 590 PRO A O   1 
ATOM   4222 C  CB  . PRO A 1 590 ? 176.091 185.057 156.579 1.00 120.48 ? 590 PRO A CB  1 
ATOM   4223 C  CG  . PRO A 1 590 ? 174.832 185.520 155.913 1.00 120.48 ? 590 PRO A CG  1 
ATOM   4224 C  CD  . PRO A 1 590 ? 175.053 186.959 155.596 1.00 120.48 ? 590 PRO A CD  1 
ATOM   4225 N  N   . SER A 1 591 ? 178.877 185.562 157.893 1.00 123.75 ? 591 SER A N   1 
ATOM   4226 C  CA  . SER A 1 591 ? 180.327 185.659 157.968 1.00 123.75 ? 591 SER A CA  1 
ATOM   4227 C  C   . SER A 1 591 ? 180.966 184.463 157.278 1.00 123.75 ? 591 SER A C   1 
ATOM   4228 O  O   . SER A 1 591 ? 180.532 183.323 157.475 1.00 123.75 ? 591 SER A O   1 
ATOM   4229 C  CB  . SER A 1 591 ? 180.792 185.740 159.425 1.00 123.75 ? 591 SER A CB  1 
ATOM   4230 O  OG  . SER A 1 591 ? 182.206 185.708 159.515 1.00 123.75 ? 591 SER A OG  1 
ATOM   4231 N  N   . THR A 1 592 ? 181.995 184.736 156.478 1.00 123.69 ? 592 THR A N   1 
ATOM   4232 C  CA  . THR A 1 592 ? 182.851 183.769 155.770 1.00 123.69 ? 592 THR A CA  1 
ATOM   4233 C  C   . THR A 1 592 ? 181.986 182.891 154.860 1.00 123.69 ? 592 THR A C   1 
ATOM   4234 O  O   . THR A 1 592 ? 180.925 183.318 154.386 1.00 123.69 ? 592 THR A O   1 
ATOM   4235 C  CB  . THR A 1 592 ? 183.710 182.991 156.765 1.00 123.69 ? 592 THR A CB  1 
ATOM   4236 O  OG1 . THR A 1 592 ? 182.893 182.075 157.505 1.00 123.69 ? 592 THR A OG1 1 
ATOM   4237 C  CG2 . THR A 1 592 ? 184.417 183.938 157.727 1.00 123.69 ? 592 THR A CG2 1 
ATOM   4238 N  N   . ASP A 1 593 ? 182.437 181.665 154.606 1.00 122.79 ? 593 ASP A N   1 
ATOM   4239 C  CA  . ASP A 1 593 ? 181.736 180.724 153.745 1.00 122.79 ? 593 ASP A CA  1 
ATOM   4240 C  C   . ASP A 1 593 ? 180.873 179.747 154.530 1.00 122.79 ? 593 ASP A C   1 
ATOM   4241 O  O   . ASP A 1 593 ? 180.369 178.781 153.946 1.00 122.79 ? 593 ASP A O   1 
ATOM   4242 C  CB  . ASP A 1 593 ? 182.738 179.955 152.880 1.00 122.79 ? 593 ASP A CB  1 
ATOM   4243 C  CG  . ASP A 1 593 ? 183.554 180.866 151.984 1.00 122.79 ? 593 ASP A CG  1 
ATOM   4244 O  OD1 . ASP A 1 593 ? 183.042 181.938 151.599 1.00 122.79 ? 593 ASP A OD1 1 
ATOM   4245 O  OD2 . ASP A 1 593 ? 184.708 180.510 151.665 1.00 122.79 ? 593 ASP A OD2 1 
ATOM   4246 N  N   . LEU A 1 594 ? 180.708 179.978 155.834 1.00 118.10 ? 594 LEU A N   1 
ATOM   4247 C  CA  . LEU A 1 594 ? 179.909 179.148 156.742 1.00 118.10 ? 594 LEU A CA  1 
ATOM   4248 C  C   . LEU A 1 594 ? 180.362 177.689 156.751 1.00 118.10 ? 594 LEU A C   1 
ATOM   4249 O  O   . LEU A 1 594 ? 181.554 177.398 156.643 1.00 118.10 ? 594 LEU A O   1 
ATOM   4250 C  CB  . LEU A 1 594 ? 178.419 179.232 156.388 1.00 118.10 ? 594 LEU A CB  1 
ATOM   4251 C  CG  . LEU A 1 594 ? 177.775 180.617 156.454 1.00 118.10 ? 594 LEU A CG  1 
ATOM   4252 C  CD1 . LEU A 1 594 ? 177.644 181.216 155.064 1.00 118.10 ? 594 LEU A CD1 1 
ATOM   4253 C  CD2 . LEU A 1 594 ? 176.419 180.539 157.131 1.00 118.10 ? 594 LEU A CD2 1 
ATOM   4254 N  N   . GLU B 2 1   ? 153.785 173.481 128.013 1.00 64.26  ? 1   GLU H N   1 
ATOM   4255 C  CA  . GLU B 2 1   ? 153.775 173.747 129.447 1.00 64.26  ? 1   GLU H CA  1 
ATOM   4256 C  C   . GLU B 2 1   ? 155.056 174.449 129.880 1.00 64.26  ? 1   GLU H C   1 
ATOM   4257 O  O   . GLU B 2 1   ? 155.054 175.646 130.166 1.00 64.26  ? 1   GLU H O   1 
ATOM   4258 C  CB  . GLU B 2 1   ? 153.598 172.447 130.232 1.00 64.26  ? 1   GLU H CB  1 
ATOM   4259 N  N   . VAL B 2 2   ? 156.150 173.695 129.925 1.00 62.23  ? 2   VAL H N   1 
ATOM   4260 C  CA  . VAL B 2 2   ? 157.459 174.212 130.305 1.00 62.23  ? 2   VAL H CA  1 
ATOM   4261 C  C   . VAL B 2 2   ? 158.364 174.120 129.087 1.00 62.23  ? 2   VAL H C   1 
ATOM   4262 O  O   . VAL B 2 2   ? 158.563 173.030 128.537 1.00 62.23  ? 2   VAL H O   1 
ATOM   4263 C  CB  . VAL B 2 2   ? 158.055 173.440 131.490 1.00 62.23  ? 2   VAL H CB  1 
ATOM   4264 C  CG1 . VAL B 2 2   ? 159.417 173.993 131.842 1.00 62.23  ? 2   VAL H CG1 1 
ATOM   4265 C  CG2 . VAL B 2 2   ? 157.122 173.508 132.686 1.00 62.23  ? 2   VAL H CG2 1 
ATOM   4266 N  N   . GLN B 2 3   ? 158.915 175.257 128.669 1.00 57.97  ? 3   GLN H N   1 
ATOM   4267 C  CA  . GLN B 2 3   ? 159.732 175.339 127.462 1.00 57.97  ? 3   GLN H CA  1 
ATOM   4268 C  C   . GLN B 2 3   ? 161.100 175.896 127.828 1.00 57.97  ? 3   GLN H C   1 
ATOM   4269 O  O   . GLN B 2 3   ? 161.213 177.054 128.245 1.00 57.97  ? 3   GLN H O   1 
ATOM   4270 C  CB  . GLN B 2 3   ? 159.053 176.206 126.403 1.00 57.97  ? 3   GLN H CB  1 
ATOM   4271 N  N   . LEU B 2 4   ? 162.133 175.076 127.674 1.00 52.98  ? 4   LEU H N   1 
ATOM   4272 C  CA  . LEU B 2 4   ? 163.514 175.509 127.882 1.00 52.98  ? 4   LEU H CA  1 
ATOM   4273 C  C   . LEU B 2 4   ? 164.170 175.860 126.549 1.00 52.98  ? 4   LEU H C   1 
ATOM   4274 O  O   . LEU B 2 4   ? 165.095 175.196 126.085 1.00 52.98  ? 4   LEU H O   1 
ATOM   4275 C  CB  . LEU B 2 4   ? 164.306 174.430 128.618 1.00 52.98  ? 4   LEU H CB  1 
ATOM   4276 C  CG  . LEU B 2 4   ? 164.339 174.392 130.150 1.00 52.98  ? 4   LEU H CG  1 
ATOM   4277 C  CD1 . LEU B 2 4   ? 165.020 175.636 130.690 1.00 52.98  ? 4   LEU H CD1 1 
ATOM   4278 C  CD2 . LEU B 2 4   ? 162.963 174.225 130.763 1.00 52.98  ? 4   LEU H CD2 1 
ATOM   4279 N  N   . VAL B 2 5   ? 163.672 176.926 125.923 1.00 55.41  ? 5   VAL H N   1 
ATOM   4280 C  CA  . VAL B 2 5   ? 164.239 177.363 124.654 1.00 55.41  ? 5   VAL H CA  1 
ATOM   4281 C  C   . VAL B 2 5   ? 165.600 178.010 124.902 1.00 55.41  ? 5   VAL H C   1 
ATOM   4282 O  O   . VAL B 2 5   ? 165.857 178.603 125.959 1.00 55.41  ? 5   VAL H O   1 
ATOM   4283 C  CB  . VAL B 2 5   ? 163.263 178.306 123.920 1.00 55.41  ? 5   VAL H CB  1 
ATOM   4284 C  CG1 . VAL B 2 5   ? 163.222 179.692 124.553 1.00 55.41  ? 5   VAL H CG1 1 
ATOM   4285 C  CG2 . VAL B 2 5   ? 163.593 178.386 122.433 1.00 55.41  ? 5   VAL H CG2 1 
ATOM   4286 N  N   . GLU B 2 6   ? 166.507 177.841 123.944 1.00 52.60  ? 6   GLU H N   1 
ATOM   4287 C  CA  . GLU B 2 6   ? 167.881 178.297 124.082 1.00 52.60  ? 6   GLU H CA  1 
ATOM   4288 C  C   . GLU B 2 6   ? 168.269 179.137 122.876 1.00 52.60  ? 6   GLU H C   1 
ATOM   4289 O  O   . GLU B 2 6   ? 167.596 179.117 121.842 1.00 52.60  ? 6   GLU H O   1 
ATOM   4290 C  CB  . GLU B 2 6   ? 168.857 177.125 124.216 1.00 52.60  ? 6   GLU H CB  1 
ATOM   4291 C  CG  . GLU B 2 6   ? 168.398 176.001 125.122 1.00 52.60  ? 6   GLU H CG  1 
ATOM   4292 C  CD  . GLU B 2 6   ? 169.212 174.745 124.916 1.00 52.60  ? 6   GLU H CD  1 
ATOM   4293 O  OE1 . GLU B 2 6   ? 170.162 174.786 124.108 1.00 52.60  ? 6   GLU H OE1 1 
ATOM   4294 O  OE2 . GLU B 2 6   ? 168.905 173.719 125.555 1.00 52.60  ? 6   GLU H OE2 1 
ATOM   4295 N  N   . SER B 2 7   ? 169.362 179.882 123.021 1.00 55.19  ? 7   SER H N   1 
ATOM   4296 C  CA  . SER B 2 7   ? 169.866 180.718 121.939 1.00 55.19  ? 7   SER H CA  1 
ATOM   4297 C  C   . SER B 2 7   ? 171.388 180.693 121.899 1.00 55.19  ? 7   SER H C   1 
ATOM   4298 O  O   . SER B 2 7   ? 172.021 179.901 122.604 1.00 55.19  ? 7   SER H O   1 
ATOM   4299 C  CB  . SER B 2 7   ? 169.365 182.154 122.092 1.00 55.19  ? 7   SER H CB  1 
ATOM   4300 O  OG  . SER B 2 7   ? 169.888 182.984 121.071 1.00 55.19  ? 7   SER H OG  1 
ATOM   4301 N  N   . GLY B 2 8   ? 171.982 181.558 121.086 1.00 58.22  ? 8   GLY H N   1 
ATOM   4302 C  CA  . GLY B 2 8   ? 173.423 181.598 120.977 1.00 58.22  ? 8   GLY H CA  1 
ATOM   4303 C  C   . GLY B 2 8   ? 173.961 180.460 120.125 1.00 58.22  ? 8   GLY H C   1 
ATOM   4304 O  O   . GLY B 2 8   ? 173.229 179.718 119.471 1.00 58.22  ? 8   GLY H O   1 
ATOM   4305 N  N   . GLY B 2 9   ? 175.282 180.343 120.139 1.00 61.60  ? 9   GLY H N   1 
ATOM   4306 C  CA  . GLY B 2 9   ? 175.962 179.302 119.401 1.00 61.60  ? 9   GLY H CA  1 
ATOM   4307 C  C   . GLY B 2 9   ? 176.175 179.665 117.941 1.00 61.60  ? 9   GLY H C   1 
ATOM   4308 O  O   . GLY B 2 9   ? 175.462 180.477 117.355 1.00 61.60  ? 9   GLY H O   1 
ATOM   4309 N  N   . GLY B 2 10  ? 177.174 179.029 117.348 1.00 66.10  ? 10  GLY H N   1 
ATOM   4310 C  CA  . GLY B 2 10  ? 177.554 179.281 115.979 1.00 66.10  ? 10  GLY H CA  1 
ATOM   4311 C  C   . GLY B 2 10  ? 178.999 178.900 115.759 1.00 66.10  ? 10  GLY H C   1 
ATOM   4312 O  O   . GLY B 2 10  ? 179.531 178.015 116.426 1.00 66.10  ? 10  GLY H O   1 
ATOM   4313 N  N   . LEU B 2 11  ? 179.635 179.577 114.807 1.00 72.55  ? 11  LEU H N   1 
ATOM   4314 C  CA  . LEU B 2 11  ? 181.032 179.313 114.498 1.00 72.55  ? 11  LEU H CA  1 
ATOM   4315 C  C   . LEU B 2 11  ? 181.915 180.364 115.157 1.00 72.55  ? 11  LEU H C   1 
ATOM   4316 O  O   . LEU B 2 11  ? 181.694 181.567 114.989 1.00 72.55  ? 11  LEU H O   1 
ATOM   4317 C  CB  . LEU B 2 11  ? 181.253 179.306 112.985 1.00 72.55  ? 11  LEU H CB  1 
ATOM   4318 C  CG  . LEU B 2 11  ? 182.699 179.346 112.482 1.00 72.55  ? 11  LEU H CG  1 
ATOM   4319 C  CD1 . LEU B 2 11  ? 183.506 178.160 113.000 1.00 72.55  ? 11  LEU H CD1 1 
ATOM   4320 C  CD2 . LEU B 2 11  ? 182.740 179.402 110.967 1.00 72.55  ? 11  LEU H CD2 1 
ATOM   4321 N  N   . VAL B 2 12  ? 182.917 179.908 115.905 1.00 72.31  ? 12  VAL H N   1 
ATOM   4322 C  CA  . VAL B 2 12  ? 183.866 180.793 116.565 1.00 72.31  ? 12  VAL H CA  1 
ATOM   4323 C  C   . VAL B 2 12  ? 185.278 180.310 116.276 1.00 72.31  ? 12  VAL H C   1 
ATOM   4324 O  O   . VAL B 2 12  ? 185.511 179.126 116.010 1.00 72.31  ? 12  VAL H O   1 
ATOM   4325 C  CB  . VAL B 2 12  ? 183.623 180.869 118.087 1.00 72.31  ? 12  VAL H CB  1 
ATOM   4326 C  CG1 . VAL B 2 12  ? 182.381 181.687 118.387 1.00 72.31  ? 12  VAL H CG1 1 
ATOM   4327 C  CG2 . VAL B 2 12  ? 183.496 179.476 118.668 1.00 72.31  ? 12  VAL H CG2 1 
ATOM   4328 N  N   . LYS B 2 13  ? 186.225 181.240 116.329 1.00 76.20  ? 13  LYS H N   1 
ATOM   4329 C  CA  . LYS B 2 13  ? 187.620 180.905 116.109 1.00 76.20  ? 13  LYS H CA  1 
ATOM   4330 C  C   . LYS B 2 13  ? 188.183 180.190 117.337 1.00 76.20  ? 13  LYS H C   1 
ATOM   4331 O  O   . LYS B 2 13  ? 187.681 180.373 118.450 1.00 76.20  ? 13  LYS H O   1 
ATOM   4332 C  CB  . LYS B 2 13  ? 188.439 182.163 115.813 1.00 76.20  ? 13  LYS H CB  1 
ATOM   4333 C  CG  . LYS B 2 13  ? 188.394 182.651 114.361 1.00 76.20  ? 13  LYS H CG  1 
ATOM   4334 C  CD  . LYS B 2 13  ? 187.083 183.341 114.005 1.00 76.20  ? 13  LYS H CD  1 
ATOM   4335 C  CE  . LYS B 2 13  ? 187.106 183.887 112.588 1.00 76.20  ? 13  LYS H CE  1 
ATOM   4336 N  NZ  . LYS B 2 13  ? 185.786 184.455 112.200 1.00 76.20  ? 13  LYS H NZ  1 
ATOM   4337 N  N   . PRO B 2 14  ? 189.202 179.344 117.160 1.00 77.51  ? 14  PRO H N   1 
ATOM   4338 C  CA  . PRO B 2 14  ? 189.855 178.728 118.325 1.00 77.51  ? 14  PRO H CA  1 
ATOM   4339 C  C   . PRO B 2 14  ? 190.532 179.779 119.192 1.00 77.51  ? 14  PRO H C   1 
ATOM   4340 O  O   . PRO B 2 14  ? 191.172 180.704 118.688 1.00 77.51  ? 14  PRO H O   1 
ATOM   4341 C  CB  . PRO B 2 14  ? 190.872 177.765 117.700 1.00 77.51  ? 14  PRO H CB  1 
ATOM   4342 C  CG  . PRO B 2 14  ? 191.067 178.258 116.309 1.00 77.51  ? 14  PRO H CG  1 
ATOM   4343 C  CD  . PRO B 2 14  ? 189.745 178.823 115.895 1.00 77.51  ? 14  PRO H CD  1 
ATOM   4344 N  N   . GLY B 2 15  ? 190.382 179.629 120.505 1.00 75.25  ? 15  GLY H N   1 
ATOM   4345 C  CA  . GLY B 2 15  ? 190.846 180.626 121.443 1.00 75.25  ? 15  GLY H CA  1 
ATOM   4346 C  C   . GLY B 2 15  ? 189.919 181.806 121.628 1.00 75.25  ? 15  GLY H C   1 
ATOM   4347 O  O   . GLY B 2 15  ? 190.263 182.729 122.377 1.00 75.25  ? 15  GLY H O   1 
ATOM   4348 N  N   . GLY B 2 16  ? 188.757 181.809 120.979 1.00 73.14  ? 16  GLY H N   1 
ATOM   4349 C  CA  . GLY B 2 16  ? 187.828 182.915 121.083 1.00 73.14  ? 16  GLY H CA  1 
ATOM   4350 C  C   . GLY B 2 16  ? 186.876 182.786 122.253 1.00 73.14  ? 16  GLY H C   1 
ATOM   4351 O  O   . GLY B 2 16  ? 187.197 182.133 123.250 1.00 73.14  ? 16  GLY H O   1 
ATOM   4352 N  N   . SER B 2 17  ? 185.700 183.402 122.146 1.00 66.15  ? 17  SER H N   1 
ATOM   4353 C  CA  . SER B 2 17  ? 184.733 183.385 123.232 1.00 66.15  ? 17  SER H CA  1 
ATOM   4354 C  C   . SER B 2 17  ? 183.326 183.472 122.661 1.00 66.15  ? 17  SER H C   1 
ATOM   4355 O  O   . SER B 2 17  ? 183.124 183.937 121.537 1.00 66.15  ? 17  SER H O   1 
ATOM   4356 C  CB  . SER B 2 17  ? 184.977 184.534 124.215 1.00 66.15  ? 17  SER H CB  1 
ATOM   4357 O  OG  . SER B 2 17  ? 184.063 184.477 125.295 1.00 66.15  ? 17  SER H OG  1 
ATOM   4358 N  N   . LEU B 2 18  ? 182.354 183.018 123.451 1.00 60.84  ? 18  LEU H N   1 
ATOM   4359 C  CA  . LEU B 2 18  ? 180.953 183.037 123.059 1.00 60.84  ? 18  LEU H CA  1 
ATOM   4360 C  C   . LEU B 2 18  ? 180.091 183.124 124.311 1.00 60.84  ? 18  LEU H C   1 
ATOM   4361 O  O   . LEU B 2 18  ? 180.525 182.780 125.412 1.00 60.84  ? 18  LEU H O   1 
ATOM   4362 C  CB  . LEU B 2 18  ? 180.590 181.797 122.228 1.00 60.84  ? 18  LEU H CB  1 
ATOM   4363 C  CG  . LEU B 2 18  ? 179.350 181.859 121.332 1.00 60.84  ? 18  LEU H CG  1 
ATOM   4364 C  CD1 . LEU B 2 18  ? 179.298 183.172 120.572 1.00 60.84  ? 18  LEU H CD1 1 
ATOM   4365 C  CD2 . LEU B 2 18  ? 179.324 180.683 120.372 1.00 60.84  ? 18  LEU H CD2 1 
ATOM   4366 N  N   . LYS B 2 19  ? 178.855 183.590 124.132 1.00 54.10  ? 19  LYS H N   1 
ATOM   4367 C  CA  . LYS B 2 19  ? 177.919 183.800 125.235 1.00 54.10  ? 19  LYS H CA  1 
ATOM   4368 C  C   . LYS B 2 19  ? 176.587 183.147 124.877 1.00 54.10  ? 19  LYS H C   1 
ATOM   4369 O  O   . LYS B 2 19  ? 175.801 183.709 124.110 1.00 54.10  ? 19  LYS H O   1 
ATOM   4370 C  CB  . LYS B 2 19  ? 177.744 185.288 125.520 1.00 54.10  ? 19  LYS H CB  1 
ATOM   4371 C  CG  . LYS B 2 19  ? 176.833 185.606 126.693 1.00 54.10  ? 19  LYS H CG  1 
ATOM   4372 C  CD  . LYS B 2 19  ? 177.609 185.606 127.999 1.00 54.10  ? 19  LYS H CD  1 
ATOM   4373 C  CE  . LYS B 2 19  ? 176.731 186.010 129.168 1.00 54.10  ? 19  LYS H CE  1 
ATOM   4374 N  NZ  . LYS B 2 19  ? 175.764 187.074 128.789 1.00 54.10  ? 19  LYS H NZ  1 
ATOM   4375 N  N   . LEU B 2 20  ? 176.334 181.966 125.435 1.00 52.66  ? 20  LEU H N   1 
ATOM   4376 C  CA  . LEU B 2 20  ? 175.084 181.260 125.191 1.00 52.66  ? 20  LEU H CA  1 
ATOM   4377 C  C   . LEU B 2 20  ? 174.002 181.740 126.148 1.00 52.66  ? 20  LEU H C   1 
ATOM   4378 O  O   . LEU B 2 20  ? 174.292 182.204 127.253 1.00 52.66  ? 20  LEU H O   1 
ATOM   4379 C  CB  . LEU B 2 20  ? 175.282 179.750 125.333 1.00 52.66  ? 20  LEU H CB  1 
ATOM   4380 C  CG  . LEU B 2 20  ? 175.556 178.970 124.045 1.00 52.66  ? 20  LEU H CG  1 
ATOM   4381 C  CD1 . LEU B 2 20  ? 176.877 179.363 123.417 1.00 52.66  ? 20  LEU H CD1 1 
ATOM   4382 C  CD2 . LEU B 2 20  ? 175.532 177.481 124.318 1.00 52.66  ? 20  LEU H CD2 1 
ATOM   4383 N  N   . SER B 2 21  ? 172.749 181.631 125.712 1.00 53.01  ? 21  SER H N   1 
ATOM   4384 C  CA  . SER B 2 21  ? 171.607 182.109 126.480 1.00 53.01  ? 21  SER H CA  1 
ATOM   4385 C  C   . SER B 2 21  ? 170.541 181.028 126.546 1.00 53.01  ? 21  SER H C   1 
ATOM   4386 O  O   . SER B 2 21  ? 170.185 180.440 125.520 1.00 53.01  ? 21  SER H O   1 
ATOM   4387 C  CB  . SER B 2 21  ? 171.020 183.379 125.860 1.00 53.01  ? 21  SER H CB  1 
ATOM   4388 O  OG  . SER B 2 21  ? 169.745 183.666 126.405 1.00 53.01  ? 21  SER H OG  1 
ATOM   4389 N  N   . CYS B 2 22  ? 170.031 180.770 127.746 1.00 55.79  ? 22  CYS H N   1 
ATOM   4390 C  CA  . CYS B 2 22  ? 168.907 179.865 127.951 1.00 55.79  ? 22  CYS H CA  1 
ATOM   4391 C  C   . CYS B 2 22  ? 167.741 180.663 128.509 1.00 55.79  ? 22  CYS H C   1 
ATOM   4392 O  O   . CYS B 2 22  ? 167.874 181.311 129.552 1.00 55.79  ? 22  CYS H O   1 
ATOM   4393 C  CB  . CYS B 2 22  ? 169.271 178.718 128.897 1.00 55.79  ? 22  CYS H CB  1 
ATOM   4394 S  SG  . CYS B 2 22  ? 167.924 177.528 129.162 1.00 55.79  ? 22  CYS H SG  1 
ATOM   4395 N  N   . ALA B 2 23  ? 166.605 180.615 127.822 1.00 56.60  ? 23  ALA H N   1 
ATOM   4396 C  CA  . ALA B 2 23  ? 165.383 181.260 128.277 1.00 56.60  ? 23  ALA H CA  1 
ATOM   4397 C  C   . ALA B 2 23  ? 164.451 180.203 128.847 1.00 56.60  ? 23  ALA H C   1 
ATOM   4398 O  O   . ALA B 2 23  ? 164.097 179.245 128.154 1.00 56.60  ? 23  ALA H O   1 
ATOM   4399 C  CB  . ALA B 2 23  ? 164.697 182.016 127.138 1.00 56.60  ? 23  ALA H CB  1 
ATOM   4400 N  N   . ALA B 2 24  ? 164.057 180.379 130.102 1.00 58.67  ? 24  ALA H N   1 
ATOM   4401 C  CA  . ALA B 2 24  ? 163.160 179.453 130.772 1.00 58.67  ? 24  ALA H CA  1 
ATOM   4402 C  C   . ALA B 2 24  ? 161.831 180.139 131.047 1.00 58.67  ? 24  ALA H C   1 
ATOM   4403 O  O   . ALA B 2 24  ? 161.783 181.326 131.382 1.00 58.67  ? 24  ALA H O   1 
ATOM   4404 C  CB  . ALA B 2 24  ? 163.766 178.938 132.078 1.00 58.67  ? 24  ALA H CB  1 
ATOM   4405 N  N   . SER B 2 25  ? 160.748 179.380 130.904 1.00 63.63  ? 25  SER H N   1 
ATOM   4406 C  CA  . SER B 2 25  ? 159.413 179.932 131.070 1.00 63.63  ? 25  SER H CA  1 
ATOM   4407 C  C   . SER B 2 25  ? 158.456 178.823 131.480 1.00 63.63  ? 25  SER H C   1 
ATOM   4408 O  O   . SER B 2 25  ? 158.751 177.635 131.335 1.00 63.63  ? 25  SER H O   1 
ATOM   4409 C  CB  . SER B 2 25  ? 158.928 180.616 129.788 1.00 63.63  ? 25  SER H CB  1 
ATOM   4410 O  OG  . SER B 2 25  ? 158.752 179.673 128.746 1.00 63.63  ? 25  SER H OG  1 
ATOM   4411 N  N   . GLY B 2 26  ? 157.300 179.233 131.997 1.00 64.77  ? 26  GLY H N   1 
ATOM   4412 C  CA  . GLY B 2 26  ? 156.288 178.303 132.447 1.00 64.77  ? 26  GLY H CA  1 
ATOM   4413 C  C   . GLY B 2 26  ? 156.477 177.770 133.848 1.00 64.77  ? 26  GLY H C   1 
ATOM   4414 O  O   . GLY B 2 26  ? 155.674 176.936 134.286 1.00 64.77  ? 26  GLY H O   1 
ATOM   4415 N  N   . PHE B 2 27  ? 157.501 178.220 134.567 1.00 61.96  ? 27  PHE H N   1 
ATOM   4416 C  CA  . PHE B 2 27  ? 157.755 177.756 135.923 1.00 61.96  ? 27  PHE H CA  1 
ATOM   4417 C  C   . PHE B 2 27  ? 158.585 178.807 136.645 1.00 61.96  ? 27  PHE H C   1 
ATOM   4418 O  O   . PHE B 2 27  ? 159.117 179.736 136.034 1.00 61.96  ? 27  PHE H O   1 
ATOM   4419 C  CB  . PHE B 2 27  ? 158.461 176.394 135.931 1.00 61.96  ? 27  PHE H CB  1 
ATOM   4420 C  CG  . PHE B 2 27  ? 159.907 176.455 135.523 1.00 61.96  ? 27  PHE H CG  1 
ATOM   4421 C  CD1 . PHE B 2 27  ? 160.260 176.588 134.192 1.00 61.96  ? 27  PHE H CD1 1 
ATOM   4422 C  CD2 . PHE B 2 27  ? 160.912 176.368 136.471 1.00 61.96  ? 27  PHE H CD2 1 
ATOM   4423 C  CE1 . PHE B 2 27  ? 161.584 176.641 133.814 1.00 61.96  ? 27  PHE H CE1 1 
ATOM   4424 C  CE2 . PHE B 2 27  ? 162.237 176.424 136.098 1.00 61.96  ? 27  PHE H CE2 1 
ATOM   4425 C  CZ  . PHE B 2 27  ? 162.572 176.559 134.767 1.00 61.96  ? 27  PHE H CZ  1 
ATOM   4426 N  N   . THR B 2 28  ? 158.692 178.644 137.961 1.00 65.28  ? 28  THR H N   1 
ATOM   4427 C  CA  . THR B 2 28  ? 159.484 179.547 138.788 1.00 65.28  ? 28  THR H CA  1 
ATOM   4428 C  C   . THR B 2 28  ? 160.961 179.256 138.555 1.00 65.28  ? 28  THR H C   1 
ATOM   4429 O  O   . THR B 2 28  ? 161.487 178.250 139.040 1.00 65.28  ? 28  THR H O   1 
ATOM   4430 C  CB  . THR B 2 28  ? 159.118 179.385 140.260 1.00 65.28  ? 28  THR H CB  1 
ATOM   4431 O  OG1 . THR B 2 28  ? 159.209 178.003 140.625 1.00 65.28  ? 28  THR H OG1 1 
ATOM   4432 C  CG2 . THR B 2 28  ? 157.701 179.873 140.509 1.00 65.28  ? 28  THR H CG2 1 
ATOM   4433 N  N   . PHE B 2 29  ? 161.631 180.140 137.812 1.00 59.84  ? 29  PHE H N   1 
ATOM   4434 C  CA  . PHE B 2 29  ? 163.029 179.916 137.459 1.00 59.84  ? 29  PHE H CA  1 
ATOM   4435 C  C   . PHE B 2 29  ? 163.953 180.051 138.662 1.00 59.84  ? 29  PHE H C   1 
ATOM   4436 O  O   . PHE B 2 29  ? 164.997 179.392 138.715 1.00 59.84  ? 29  PHE H O   1 
ATOM   4437 C  CB  . PHE B 2 29  ? 163.444 180.888 136.357 1.00 59.84  ? 29  PHE H CB  1 
ATOM   4438 C  CG  . PHE B 2 29  ? 164.883 180.775 135.956 1.00 59.84  ? 29  PHE H CG  1 
ATOM   4439 C  CD1 . PHE B 2 29  ? 165.330 179.691 135.225 1.00 59.84  ? 29  PHE H CD1 1 
ATOM   4440 C  CD2 . PHE B 2 29  ? 165.788 181.762 136.303 1.00 59.84  ? 29  PHE H CD2 1 
ATOM   4441 C  CE1 . PHE B 2 29  ? 166.654 179.591 134.852 1.00 59.84  ? 29  PHE H CE1 1 
ATOM   4442 C  CE2 . PHE B 2 29  ? 167.113 181.666 135.933 1.00 59.84  ? 29  PHE H CE2 1 
ATOM   4443 C  CZ  . PHE B 2 29  ? 167.547 180.579 135.207 1.00 59.84  ? 29  PHE H CZ  1 
ATOM   4444 N  N   . SER B 2 30  ? 163.591 180.883 139.635 1.00 58.94  ? 30  SER H N   1 
ATOM   4445 C  CA  . SER B 2 30  ? 164.446 181.092 140.794 1.00 58.94  ? 30  SER H CA  1 
ATOM   4446 C  C   . SER B 2 30  ? 164.358 179.964 141.813 1.00 58.94  ? 30  SER H C   1 
ATOM   4447 O  O   . SER B 2 30  ? 165.173 179.929 142.741 1.00 58.94  ? 30  SER H O   1 
ATOM   4448 C  CB  . SER B 2 30  ? 164.098 182.419 141.472 1.00 58.94  ? 30  SER H CB  1 
ATOM   4449 N  N   . SER B 2 31  ? 163.404 179.048 141.669 1.00 59.36  ? 31  SER H N   1 
ATOM   4450 C  CA  . SER B 2 31  ? 163.223 177.963 142.622 1.00 59.36  ? 31  SER H CA  1 
ATOM   4451 C  C   . SER B 2 31  ? 163.765 176.629 142.127 1.00 59.36  ? 31  SER H C   1 
ATOM   4452 O  O   . SER B 2 31  ? 163.543 175.608 142.784 1.00 59.36  ? 31  SER H O   1 
ATOM   4453 C  CB  . SER B 2 31  ? 161.741 177.815 142.976 1.00 59.36  ? 31  SER H CB  1 
ATOM   4454 O  OG  . SER B 2 31  ? 161.320 178.856 143.839 1.00 59.36  ? 31  SER H OG  1 
ATOM   4455 N  N   . TYR B 2 32  ? 164.457 176.605 140.990 1.00 55.25  ? 32  TYR H N   1 
ATOM   4456 C  CA  . TYR B 2 32  ? 165.056 175.382 140.472 1.00 55.25  ? 32  TYR H CA  1 
ATOM   4457 C  C   . TYR B 2 32  ? 166.458 175.679 139.967 1.00 55.25  ? 32  TYR H C   1 
ATOM   4458 O  O   . TYR B 2 32  ? 166.679 176.693 139.300 1.00 55.25  ? 32  TYR H O   1 
ATOM   4459 C  CB  . TYR B 2 32  ? 164.207 174.777 139.352 1.00 55.25  ? 32  TYR H CB  1 
ATOM   4460 C  CG  . TYR B 2 32  ? 162.847 174.309 139.808 1.00 55.25  ? 32  TYR H CG  1 
ATOM   4461 C  CD1 . TYR B 2 32  ? 162.670 173.039 140.338 1.00 55.25  ? 32  TYR H CD1 1 
ATOM   4462 C  CD2 . TYR B 2 32  ? 161.738 175.136 139.703 1.00 55.25  ? 32  TYR H CD2 1 
ATOM   4463 C  CE1 . TYR B 2 32  ? 161.426 172.608 140.758 1.00 55.25  ? 32  TYR H CE1 1 
ATOM   4464 C  CE2 . TYR B 2 32  ? 160.491 174.714 140.117 1.00 55.25  ? 32  TYR H CE2 1 
ATOM   4465 C  CZ  . TYR B 2 32  ? 160.340 173.450 140.643 1.00 55.25  ? 32  TYR H CZ  1 
ATOM   4466 O  OH  . TYR B 2 32  ? 159.098 173.027 141.057 1.00 55.25  ? 32  TYR H OH  1 
ATOM   4467 N  N   . ALA B 2 33  ? 167.398 174.792 140.282 1.00 48.41  ? 33  ALA H N   1 
ATOM   4468 C  CA  . ALA B 2 33  ? 168.763 174.949 139.811 1.00 48.41  ? 33  ALA H CA  1 
ATOM   4469 C  C   . ALA B 2 33  ? 168.855 174.613 138.326 1.00 48.41  ? 33  ALA H C   1 
ATOM   4470 O  O   . ALA B 2 33  ? 167.913 174.102 137.717 1.00 48.41  ? 33  ALA H O   1 
ATOM   4471 C  CB  . ALA B 2 33  ? 169.714 174.066 140.616 1.00 48.41  ? 33  ALA H CB  1 
ATOM   4472 N  N   . MET B 2 34  ? 170.010 174.911 137.741 1.00 45.85  ? 34  MET H N   1 
ATOM   4473 C  CA  . MET B 2 34  ? 170.209 174.773 136.309 1.00 45.85  ? 34  MET H CA  1 
ATOM   4474 C  C   . MET B 2 34  ? 171.568 174.154 136.027 1.00 45.85  ? 34  MET H C   1 
ATOM   4475 O  O   . MET B 2 34  ? 172.489 174.227 136.843 1.00 45.85  ? 34  MET H O   1 
ATOM   4476 C  CB  . MET B 2 34  ? 170.103 176.126 135.605 1.00 45.85  ? 34  MET H CB  1 
ATOM   4477 C  CG  . MET B 2 34  ? 168.684 176.577 135.339 1.00 45.85  ? 34  MET H CG  1 
ATOM   4478 S  SD  . MET B 2 34  ? 167.684 175.254 134.652 1.00 45.85  ? 34  MET H SD  1 
ATOM   4479 C  CE  . MET B 2 34  ? 166.098 176.060 134.528 1.00 45.85  ? 34  MET H CE  1 
ATOM   4480 N  N   . SER B 2 35  ? 171.682 173.536 134.854 1.00 42.17  ? 35  SER H N   1 
ATOM   4481 C  CA  . SER B 2 35  ? 172.942 172.958 134.416 1.00 42.17  ? 35  SER H CA  1 
ATOM   4482 C  C   . SER B 2 35  ? 173.019 173.019 132.900 1.00 42.17  ? 35  SER H C   1 
ATOM   4483 O  O   . SER B 2 35  ? 172.001 173.054 132.207 1.00 42.17  ? 35  SER H O   1 
ATOM   4484 C  CB  . SER B 2 35  ? 173.101 171.511 134.889 1.00 42.17  ? 35  SER H CB  1 
ATOM   4485 O  OG  . SER B 2 35  ? 173.001 171.416 136.297 1.00 42.17  ? 35  SER H OG  1 
ATOM   4486 N  N   . TRP B 2 36  ? 174.246 173.028 132.395 1.00 42.75  ? 36  TRP H N   1 
ATOM   4487 C  CA  . TRP B 2 36  ? 174.517 172.970 130.967 1.00 42.75  ? 36  TRP H CA  1 
ATOM   4488 C  C   . TRP B 2 36  ? 175.187 171.643 130.653 1.00 42.75  ? 36  TRP H C   1 
ATOM   4489 O  O   . TRP B 2 36  ? 176.256 171.344 131.193 1.00 42.75  ? 36  TRP H O   1 
ATOM   4490 C  CB  . TRP B 2 36  ? 175.413 174.129 130.529 1.00 42.75  ? 36  TRP H CB  1 
ATOM   4491 C  CG  . TRP B 2 36  ? 174.699 175.431 130.409 1.00 42.75  ? 36  TRP H CG  1 
ATOM   4492 C  CD1 . TRP B 2 36  ? 174.478 176.333 131.401 1.00 42.75  ? 36  TRP H CD1 1 
ATOM   4493 C  CD2 . TRP B 2 36  ? 174.125 175.990 129.223 1.00 42.75  ? 36  TRP H CD2 1 
ATOM   4494 N  NE1 . TRP B 2 36  ? 173.796 177.417 130.912 1.00 42.75  ? 36  TRP H NE1 1 
ATOM   4495 C  CE2 . TRP B 2 36  ? 173.565 177.229 129.576 1.00 42.75  ? 36  TRP H CE2 1 
ATOM   4496 C  CE3 . TRP B 2 36  ? 174.026 175.561 127.899 1.00 42.75  ? 36  TRP H CE3 1 
ATOM   4497 C  CZ2 . TRP B 2 36  ? 172.917 178.043 128.655 1.00 42.75  ? 36  TRP H CZ2 1 
ATOM   4498 C  CZ3 . TRP B 2 36  ? 173.381 176.370 126.987 1.00 42.75  ? 36  TRP H CZ3 1 
ATOM   4499 C  CH2 . TRP B 2 36  ? 172.836 177.596 127.368 1.00 42.75  ? 36  TRP H CH2 1 
ATOM   4500 N  N   . VAL B 2 37  ? 174.563 170.850 129.790 1.00 41.63  ? 37  VAL H N   1 
ATOM   4501 C  CA  . VAL B 2 37  ? 175.083 169.548 129.395 1.00 41.63  ? 37  VAL H CA  1 
ATOM   4502 C  C   . VAL B 2 37  ? 175.364 169.583 127.902 1.00 41.63  ? 37  VAL H C   1 
ATOM   4503 O  O   . VAL B 2 37  ? 174.472 169.894 127.106 1.00 41.63  ? 37  VAL H O   1 
ATOM   4504 C  CB  . VAL B 2 37  ? 174.100 168.415 129.739 1.00 41.63  ? 37  VAL H CB  1 
ATOM   4505 C  CG1 . VAL B 2 37  ? 174.729 167.078 129.445 1.00 41.63  ? 37  VAL H CG1 1 
ATOM   4506 C  CG2 . VAL B 2 37  ? 173.689 168.495 131.192 1.00 41.63  ? 37  VAL H CG2 1 
ATOM   4507 N  N   . ARG B 2 38  ? 176.596 169.267 127.524 1.00 42.97  ? 38  ARG H N   1 
ATOM   4508 C  CA  . ARG B 2 38  ? 177.009 169.300 126.131 1.00 42.97  ? 38  ARG H CA  1 
ATOM   4509 C  C   . ARG B 2 38  ? 177.026 167.891 125.556 1.00 42.97  ? 38  ARG H C   1 
ATOM   4510 O  O   . ARG B 2 38  ? 177.110 166.899 126.283 1.00 42.97  ? 38  ARG H O   1 
ATOM   4511 C  CB  . ARG B 2 38  ? 178.388 169.947 125.984 1.00 42.97  ? 38  ARG H CB  1 
ATOM   4512 C  CG  . ARG B 2 38  ? 179.544 169.044 126.344 1.00 42.97  ? 38  ARG H CG  1 
ATOM   4513 C  CD  . ARG B 2 38  ? 180.863 169.651 125.914 1.00 42.97  ? 38  ARG H CD  1 
ATOM   4514 N  NE  . ARG B 2 38  ? 181.968 169.180 126.737 1.00 42.97  ? 38  ARG H NE  1 
ATOM   4515 C  CZ  . ARG B 2 38  ? 182.967 169.945 127.151 1.00 42.97  ? 38  ARG H CZ  1 
ATOM   4516 N  NH1 . ARG B 2 38  ? 183.022 171.230 126.848 1.00 42.97  ? 38  ARG H NH1 1 
ATOM   4517 N  NH2 . ARG B 2 38  ? 183.931 169.409 127.894 1.00 42.97  ? 38  ARG H NH2 1 
ATOM   4518 N  N   . GLN B 2 39  ? 176.928 167.815 124.231 1.00 48.23  ? 39  GLN H N   1 
ATOM   4519 C  CA  . GLN B 2 39  ? 176.947 166.546 123.513 1.00 48.23  ? 39  GLN H CA  1 
ATOM   4520 C  C   . GLN B 2 39  ? 177.987 166.614 122.408 1.00 48.23  ? 39  GLN H C   1 
ATOM   4521 O  O   . GLN B 2 39  ? 177.826 167.379 121.452 1.00 48.23  ? 39  GLN H O   1 
ATOM   4522 C  CB  . GLN B 2 39  ? 175.578 166.213 122.920 1.00 48.23  ? 39  GLN H CB  1 
ATOM   4523 C  CG  . GLN B 2 39  ? 175.524 164.828 122.309 1.00 48.23  ? 39  GLN H CG  1 
ATOM   4524 C  CD  . GLN B 2 39  ? 174.135 164.237 122.315 1.00 48.23  ? 39  GLN H CD  1 
ATOM   4525 O  OE1 . GLN B 2 39  ? 173.156 164.928 122.589 1.00 48.23  ? 39  GLN H OE1 1 
ATOM   4526 N  NE2 . GLN B 2 39  ? 174.040 162.947 122.015 1.00 48.23  ? 39  GLN H NE2 1 
ATOM   4527 N  N   . SER B 2 40  ? 179.023 165.790 122.523 1.00 51.43  ? 40  SER H N   1 
ATOM   4528 C  CA  . SER B 2 40  ? 180.085 165.748 121.535 1.00 51.43  ? 40  SER H CA  1 
ATOM   4529 C  C   . SER B 2 40  ? 179.552 165.219 120.203 1.00 51.43  ? 40  SER H C   1 
ATOM   4530 O  O   . SER B 2 40  ? 178.513 164.557 120.163 1.00 51.43  ? 40  SER H O   1 
ATOM   4531 C  CB  . SER B 2 40  ? 181.227 164.868 122.041 1.00 51.43  ? 40  SER H CB  1 
ATOM   4532 O  OG  . SER B 2 40  ? 181.820 165.422 123.203 1.00 51.43  ? 40  SER H OG  1 
ATOM   4533 N  N   . PRO B 2 41  ? 180.232 165.525 119.091 1.00 53.73  ? 41  PRO H N   1 
ATOM   4534 C  CA  . PRO B 2 41  ? 179.817 164.947 117.799 1.00 53.73  ? 41  PRO H CA  1 
ATOM   4535 C  C   . PRO B 2 41  ? 179.912 163.430 117.740 1.00 53.73  ? 41  PRO H C   1 
ATOM   4536 O  O   . PRO B 2 41  ? 179.276 162.820 116.872 1.00 53.73  ? 41  PRO H O   1 
ATOM   4537 C  CB  . PRO B 2 41  ? 180.771 165.609 116.793 1.00 53.73  ? 41  PRO H CB  1 
ATOM   4538 C  CG  . PRO B 2 41  ? 181.893 166.155 117.615 1.00 53.73  ? 41  PRO H CG  1 
ATOM   4539 C  CD  . PRO B 2 41  ? 181.270 166.552 118.909 1.00 53.73  ? 41  PRO H CD  1 
ATOM   4540 N  N   . GLU B 2 42  ? 180.678 162.802 118.631 1.00 55.93  ? 42  GLU H N   1 
ATOM   4541 C  CA  . GLU B 2 42  ? 180.688 161.353 118.784 1.00 55.93  ? 42  GLU H CA  1 
ATOM   4542 C  C   . GLU B 2 42  ? 179.547 160.840 119.661 1.00 55.93  ? 42  GLU H C   1 
ATOM   4543 O  O   . GLU B 2 42  ? 179.591 159.677 120.081 1.00 55.93  ? 42  GLU H O   1 
ATOM   4544 C  CB  . GLU B 2 42  ? 182.035 160.902 119.357 1.00 55.93  ? 42  GLU H CB  1 
ATOM   4545 C  CG  . GLU B 2 42  ? 182.273 161.335 120.795 1.00 55.93  ? 42  GLU H CG  1 
ATOM   4546 C  CD  . GLU B 2 42  ? 183.735 161.294 121.181 1.00 55.93  ? 42  GLU H CD  1 
ATOM   4547 O  OE1 . GLU B 2 42  ? 184.586 161.159 120.277 1.00 55.93  ? 42  GLU H OE1 1 
ATOM   4548 O  OE2 . GLU B 2 42  ? 184.035 161.401 122.389 1.00 55.93  ? 42  GLU H OE2 1 
ATOM   4549 N  N   . LYS B 2 43  ? 178.543 161.685 119.927 1.00 53.07  ? 43  LYS H N   1 
ATOM   4550 C  CA  . LYS B 2 43  ? 177.363 161.354 120.735 1.00 53.07  ? 43  LYS H CA  1 
ATOM   4551 C  C   . LYS B 2 43  ? 177.748 160.914 122.147 1.00 53.07  ? 43  LYS H C   1 
ATOM   4552 O  O   . LYS B 2 43  ? 177.147 160.009 122.728 1.00 53.07  ? 43  LYS H O   1 
ATOM   4553 C  CB  . LYS B 2 43  ? 176.493 160.296 120.048 1.00 53.07  ? 43  LYS H CB  1 
ATOM   4554 C  CG  . LYS B 2 43  ? 175.924 160.736 118.713 1.00 53.07  ? 43  LYS H CG  1 
ATOM   4555 C  CD  . LYS B 2 43  ? 175.084 161.990 118.860 1.00 53.07  ? 43  LYS H CD  1 
ATOM   4556 C  CE  . LYS B 2 43  ? 175.412 162.996 117.769 1.00 53.07  ? 43  LYS H CE  1 
ATOM   4557 N  NZ  . LYS B 2 43  ? 174.814 164.330 118.046 1.00 53.07  ? 43  LYS H NZ  1 
ATOM   4558 N  N   . ARG B 2 44  ? 178.759 161.572 122.703 1.00 52.87  ? 44  ARG H N   1 
ATOM   4559 C  CA  . ARG B 2 44  ? 179.182 161.348 124.079 1.00 52.87  ? 44  ARG H CA  1 
ATOM   4560 C  C   . ARG B 2 44  ? 178.712 162.522 124.923 1.00 52.87  ? 44  ARG H C   1 
ATOM   4561 O  O   . ARG B 2 44  ? 179.097 163.668 124.668 1.00 52.87  ? 44  ARG H O   1 
ATOM   4562 C  CB  . ARG B 2 44  ? 180.698 161.184 124.175 1.00 52.87  ? 44  ARG H CB  1 
ATOM   4563 C  CG  . ARG B 2 44  ? 181.235 161.285 125.591 1.00 52.87  ? 44  ARG H CG  1 
ATOM   4564 C  CD  . ARG B 2 44  ? 182.609 160.639 125.711 1.00 52.87  ? 44  ARG H CD  1 
ATOM   4565 N  NE  . ARG B 2 44  ? 183.330 161.068 126.905 1.00 52.87  ? 44  ARG H NE  1 
ATOM   4566 C  CZ  . ARG B 2 44  ? 183.068 160.655 128.138 1.00 52.87  ? 44  ARG H CZ  1 
ATOM   4567 N  NH1 . ARG B 2 44  ? 182.116 159.771 128.388 1.00 52.87  ? 44  ARG H NH1 1 
ATOM   4568 N  NH2 . ARG B 2 44  ? 183.788 161.135 129.148 1.00 52.87  ? 44  ARG H NH2 1 
ATOM   4569 N  N   . LEU B 2 45  ? 177.884 162.236 125.920 1.00 45.61  ? 45  LEU H N   1 
ATOM   4570 C  CA  . LEU B 2 45  ? 177.286 163.257 126.767 1.00 45.61  ? 45  LEU H CA  1 
ATOM   4571 C  C   . LEU B 2 45  ? 178.175 163.493 127.980 1.00 45.61  ? 45  LEU H C   1 
ATOM   4572 O  O   . LEU B 2 45  ? 178.719 162.543 128.549 1.00 45.61  ? 45  LEU H O   1 
ATOM   4573 C  CB  . LEU B 2 45  ? 175.886 162.830 127.209 1.00 45.61  ? 45  LEU H CB  1 
ATOM   4574 C  CG  . LEU B 2 45  ? 174.845 163.925 127.418 1.00 45.61  ? 45  LEU H CG  1 
ATOM   4575 C  CD1 . LEU B 2 45  ? 174.625 164.677 126.130 1.00 45.61  ? 45  LEU H CD1 1 
ATOM   4576 C  CD2 . LEU B 2 45  ? 173.542 163.327 127.904 1.00 45.61  ? 45  LEU H CD2 1 
ATOM   4577 N  N   . GLU B 2 46  ? 178.333 164.758 128.362 1.00 47.71  ? 46  GLU H N   1 
ATOM   4578 C  CA  . GLU B 2 46  ? 179.078 165.094 129.565 1.00 47.71  ? 46  GLU H CA  1 
ATOM   4579 C  C   . GLU B 2 46  ? 178.547 166.398 130.139 1.00 47.71  ? 46  GLU H C   1 
ATOM   4580 O  O   . GLU B 2 46  ? 178.066 167.267 129.408 1.00 47.71  ? 46  GLU H O   1 
ATOM   4581 C  CB  . GLU B 2 46  ? 180.584 165.197 129.295 1.00 47.71  ? 46  GLU H CB  1 
ATOM   4582 C  CG  . GLU B 2 46  ? 180.984 166.290 128.326 1.00 47.71  ? 46  GLU H CG  1 
ATOM   4583 C  CD  . GLU B 2 46  ? 182.296 165.995 127.625 1.00 47.71  ? 46  GLU H CD  1 
ATOM   4584 O  OE1 . GLU B 2 46  ? 182.987 165.038 128.033 1.00 47.71  ? 46  GLU H OE1 1 
ATOM   4585 O  OE2 . GLU B 2 46  ? 182.639 166.722 126.670 1.00 47.71  ? 46  GLU H OE2 1 
ATOM   4586 N  N   . TRP B 2 47  ? 178.634 166.518 131.459 1.00 44.40  ? 47  TRP H N   1 
ATOM   4587 C  CA  . TRP B 2 47  ? 178.134 167.679 132.178 1.00 44.40  ? 47  TRP H CA  1 
ATOM   4588 C  C   . TRP B 2 47  ? 179.206 168.759 132.234 1.00 44.40  ? 47  TRP H C   1 
ATOM   4589 O  O   . TRP B 2 47  ? 180.390 168.464 132.412 1.00 44.40  ? 47  TRP H O   1 
ATOM   4590 C  CB  . TRP B 2 47  ? 177.703 167.269 133.586 1.00 44.40  ? 47  TRP H CB  1 
ATOM   4591 C  CG  . TRP B 2 47  ? 177.517 168.391 134.549 1.00 44.40  ? 47  TRP H CG  1 
ATOM   4592 C  CD1 . TRP B 2 47  ? 176.420 169.184 134.679 1.00 44.40  ? 47  TRP H CD1 1 
ATOM   4593 C  CD2 . TRP B 2 47  ? 178.452 168.834 135.536 1.00 44.40  ? 47  TRP H CD2 1 
ATOM   4594 N  NE1 . TRP B 2 47  ? 176.614 170.099 135.682 1.00 44.40  ? 47  TRP H NE1 1 
ATOM   4595 C  CE2 . TRP B 2 47  ? 177.856 169.905 136.224 1.00 44.40  ? 47  TRP H CE2 1 
ATOM   4596 C  CE3 . TRP B 2 47  ? 179.738 168.432 135.902 1.00 44.40  ? 47  TRP H CE3 1 
ATOM   4597 C  CZ2 . TRP B 2 47  ? 178.500 170.579 137.254 1.00 44.40  ? 47  TRP H CZ2 1 
ATOM   4598 C  CZ3 . TRP B 2 47  ? 180.375 169.101 136.926 1.00 44.40  ? 47  TRP H CZ3 1 
ATOM   4599 C  CH2 . TRP B 2 47  ? 179.756 170.163 137.590 1.00 44.40  ? 47  TRP H CH2 1 
ATOM   4600 N  N   . VAL B 2 48  ? 178.785 170.013 132.076 1.00 44.52  ? 48  VAL H N   1 
ATOM   4601 C  CA  . VAL B 2 48  ? 179.726 171.121 131.945 1.00 44.52  ? 48  VAL H CA  1 
ATOM   4602 C  C   . VAL B 2 48  ? 179.711 172.006 133.185 1.00 44.52  ? 48  VAL H C   1 
ATOM   4603 O  O   . VAL B 2 48  ? 180.750 172.214 133.820 1.00 44.52  ? 48  VAL H O   1 
ATOM   4604 C  CB  . VAL B 2 48  ? 179.424 171.947 130.684 1.00 44.52  ? 48  VAL H CB  1 
ATOM   4605 C  CG1 . VAL B 2 48  ? 180.246 173.211 130.673 1.00 44.52  ? 48  VAL H CG1 1 
ATOM   4606 C  CG2 . VAL B 2 48  ? 179.707 171.127 129.447 1.00 44.52  ? 48  VAL H CG2 1 
ATOM   4607 N  N   . ALA B 2 49  ? 178.544 172.538 133.535 1.00 46.44  ? 49  ALA H N   1 
ATOM   4608 C  CA  . ALA B 2 49  ? 178.443 173.471 134.648 1.00 46.44  ? 49  ALA H CA  1 
ATOM   4609 C  C   . ALA B 2 49  ? 177.111 173.269 135.350 1.00 46.44  ? 49  ALA H C   1 
ATOM   4610 O  O   . ALA B 2 49  ? 176.203 172.621 134.827 1.00 46.44  ? 49  ALA H O   1 
ATOM   4611 C  CB  . ALA B 2 49  ? 178.589 174.919 134.178 1.00 46.44  ? 49  ALA H CB  1 
ATOM   4612 N  N   . GLU B 2 50  ? 177.006 173.822 136.557 1.00 47.15  ? 50  GLU H N   1 
ATOM   4613 C  CA  . GLU B 2 50  ? 175.755 173.799 137.302 1.00 47.15  ? 50  GLU H CA  1 
ATOM   4614 C  C   . GLU B 2 50  ? 175.711 174.994 138.238 1.00 47.15  ? 50  GLU H C   1 
ATOM   4615 O  O   . GLU B 2 50  ? 176.654 175.219 139.001 1.00 47.15  ? 50  GLU H O   1 
ATOM   4616 C  CB  . GLU B 2 50  ? 175.596 172.503 138.105 1.00 47.15  ? 50  GLU H CB  1 
ATOM   4617 C  CG  . GLU B 2 50  ? 174.440 172.538 139.094 1.00 47.15  ? 50  GLU H CG  1 
ATOM   4618 C  CD  . GLU B 2 50  ? 174.432 171.356 140.042 1.00 47.15  ? 50  GLU H CD  1 
ATOM   4619 O  OE1 . GLU B 2 50  ? 175.361 170.527 139.971 1.00 47.15  ? 50  GLU H OE1 1 
ATOM   4620 O  OE2 . GLU B 2 50  ? 173.493 171.255 140.858 1.00 47.15  ? 50  GLU H OE2 1 
ATOM   4621 N  N   . ILE B 2 51  ? 174.618 175.749 138.180 1.00 47.60  ? 51  ILE H N   1 
ATOM   4622 C  CA  . ILE B 2 51  ? 174.393 176.874 139.076 1.00 47.60  ? 51  ILE H CA  1 
ATOM   4623 C  C   . ILE B 2 51  ? 173.185 176.552 139.947 1.00 47.60  ? 51  ILE H C   1 
ATOM   4624 O  O   . ILE B 2 51  ? 172.254 175.857 139.524 1.00 47.60  ? 51  ILE H O   1 
ATOM   4625 C  CB  . ILE B 2 51  ? 174.216 178.196 138.292 1.00 47.60  ? 51  ILE H CB  1 
ATOM   4626 C  CG1 . ILE B 2 51  ? 174.276 179.406 139.225 1.00 47.60  ? 51  ILE H CG1 1 
ATOM   4627 C  CG2 . ILE B 2 51  ? 172.934 178.197 137.473 1.00 47.60  ? 51  ILE H CG2 1 
ATOM   4628 C  CD1 . ILE B 2 51  ? 174.622 180.693 138.523 1.00 47.60  ? 51  ILE H CD1 1 
ATOM   4629 N  N   . SER B 2 52  ? 173.227 177.017 141.192 1.00 49.88  ? 52  SER H N   1 
ATOM   4630 C  CA  . SER B 2 52  ? 172.167 176.730 142.143 1.00 49.88  ? 52  SER H CA  1 
ATOM   4631 C  C   . SER B 2 52  ? 170.980 177.661 141.914 1.00 49.88  ? 52  SER H C   1 
ATOM   4632 O  O   . SER B 2 52  ? 170.997 178.540 141.049 1.00 49.88  ? 52  SER H O   1 
ATOM   4633 C  CB  . SER B 2 52  ? 172.689 176.851 143.570 1.00 49.88  ? 52  SER H CB  1 
ATOM   4634 O  OG  . SER B 2 52  ? 173.092 178.179 143.849 1.00 49.88  ? 52  SER H OG  1 
ATOM   4635 N  N   . SER B 2 53  ? 169.927 177.462 142.710 1.00 53.50  ? 53  SER H N   1 
ATOM   4636 C  CA  . SER B 2 53  ? 168.725 178.276 142.581 1.00 53.50  ? 53  SER H CA  1 
ATOM   4637 C  C   . SER B 2 53  ? 168.936 179.704 143.063 1.00 53.50  ? 53  SER H C   1 
ATOM   4638 O  O   . SER B 2 53  ? 168.198 180.601 142.643 1.00 53.50  ? 53  SER H O   1 
ATOM   4639 C  CB  . SER B 2 53  ? 167.571 177.632 143.349 1.00 53.50  ? 53  SER H CB  1 
ATOM   4640 O  OG  . SER B 2 53  ? 167.883 177.503 144.724 1.00 53.50  ? 53  SER H OG  1 
ATOM   4641 N  N   . GLY B 2 54  ? 169.916 179.935 143.930 1.00 52.46  ? 54  GLY H N   1 
ATOM   4642 C  CA  . GLY B 2 54  ? 170.223 181.278 144.379 1.00 52.46  ? 54  GLY H CA  1 
ATOM   4643 C  C   . GLY B 2 54  ? 171.257 181.949 143.501 1.00 52.46  ? 54  GLY H C   1 
ATOM   4644 O  O   . GLY B 2 54  ? 171.053 183.074 143.036 1.00 52.46  ? 54  GLY H O   1 
ATOM   4645 N  N   . GLY B 2 55  ? 172.373 181.267 143.266 1.00 54.66  ? 55  GLY H N   1 
ATOM   4646 C  CA  . GLY B 2 55  ? 173.384 181.783 142.369 1.00 54.66  ? 55  GLY H CA  1 
ATOM   4647 C  C   . GLY B 2 55  ? 174.771 181.845 142.970 1.00 54.66  ? 55  GLY H C   1 
ATOM   4648 O  O   . GLY B 2 55  ? 175.675 182.442 142.381 1.00 54.66  ? 55  GLY H O   1 
ATOM   4649 N  N   . ARG B 2 56  ? 174.959 181.235 144.140 1.00 57.74  ? 56  ARG H N   1 
ATOM   4650 C  CA  . ARG B 2 56  ? 176.254 181.250 144.803 1.00 57.74  ? 56  ARG H CA  1 
ATOM   4651 C  C   . ARG B 2 56  ? 176.867 179.871 144.992 1.00 57.74  ? 56  ARG H C   1 
ATOM   4652 O  O   . ARG B 2 56  ? 177.995 179.783 145.491 1.00 57.74  ? 56  ARG H O   1 
ATOM   4653 C  CB  . ARG B 2 56  ? 176.154 181.945 146.171 1.00 57.74  ? 56  ARG H CB  1 
ATOM   4654 C  CG  . ARG B 2 56  ? 175.083 181.380 147.077 1.00 57.74  ? 56  ARG H CG  1 
ATOM   4655 C  CD  . ARG B 2 56  ? 174.668 182.366 148.154 1.00 57.74  ? 56  ARG H CD  1 
ATOM   4656 N  NE  . ARG B 2 56  ? 173.931 181.705 149.223 1.00 57.74  ? 56  ARG H NE  1 
ATOM   4657 C  CZ  . ARG B 2 56  ? 174.499 181.115 150.266 1.00 57.74  ? 56  ARG H CZ  1 
ATOM   4658 N  NH1 . ARG B 2 56  ? 175.812 181.105 150.423 1.00 57.74  ? 56  ARG H NH1 1 
ATOM   4659 N  NH2 . ARG B 2 56  ? 173.731 180.519 151.173 1.00 57.74  ? 56  ARG H NH2 1 
ATOM   4660 N  N   . TYR B 2 57  ? 176.172 178.800 144.620 1.00 55.33  ? 57  TYR H N   1 
ATOM   4661 C  CA  . TYR B 2 57  ? 176.723 177.448 144.668 1.00 55.33  ? 57  TYR H CA  1 
ATOM   4662 C  C   . TYR B 2 57  ? 176.915 176.975 143.233 1.00 55.33  ? 57  TYR H C   1 
ATOM   4663 O  O   . TYR B 2 57  ? 175.972 176.510 142.589 1.00 55.33  ? 57  TYR H O   1 
ATOM   4664 C  CB  . TYR B 2 57  ? 175.808 176.516 145.452 1.00 55.33  ? 57  TYR H CB  1 
ATOM   4665 C  CG  . TYR B 2 57  ? 175.996 176.607 146.945 1.00 55.33  ? 57  TYR H CG  1 
ATOM   4666 C  CD1 . TYR B 2 57  ? 177.258 176.781 147.494 1.00 55.33  ? 57  TYR H CD1 1 
ATOM   4667 C  CD2 . TYR B 2 57  ? 174.911 176.529 147.804 1.00 55.33  ? 57  TYR H CD2 1 
ATOM   4668 C  CE1 . TYR B 2 57  ? 177.435 176.867 148.859 1.00 55.33  ? 57  TYR H CE1 1 
ATOM   4669 C  CE2 . TYR B 2 57  ? 175.078 176.612 149.168 1.00 55.33  ? 57  TYR H CE2 1 
ATOM   4670 C  CZ  . TYR B 2 57  ? 176.341 176.783 149.691 1.00 55.33  ? 57  TYR H CZ  1 
ATOM   4671 O  OH  . TYR B 2 57  ? 176.513 176.869 151.052 1.00 55.33  ? 57  TYR H OH  1 
ATOM   4672 N  N   . ILE B 2 58  ? 178.144 177.088 142.736 1.00 51.37  ? 58  ILE H N   1 
ATOM   4673 C  CA  . ILE B 2 58  ? 178.464 176.840 141.337 1.00 51.37  ? 58  ILE H CA  1 
ATOM   4674 C  C   . ILE B 2 58  ? 179.539 175.765 141.271 1.00 51.37  ? 58  ILE H C   1 
ATOM   4675 O  O   . ILE B 2 58  ? 180.572 175.873 141.941 1.00 51.37  ? 58  ILE H O   1 
ATOM   4676 C  CB  . ILE B 2 58  ? 178.930 178.132 140.641 1.00 51.37  ? 58  ILE H CB  1 
ATOM   4677 C  CG1 . ILE B 2 58  ? 177.746 179.067 140.414 1.00 51.37  ? 58  ILE H CG1 1 
ATOM   4678 C  CG2 . ILE B 2 58  ? 179.594 177.826 139.322 1.00 51.37  ? 58  ILE H CG2 1 
ATOM   4679 C  CD1 . ILE B 2 58  ? 178.138 180.409 139.847 1.00 51.37  ? 58  ILE H CD1 1 
ATOM   4680 N  N   . TYR B 2 59  ? 179.298 174.732 140.466 1.00 54.57  ? 59  TYR H N   1 
ATOM   4681 C  CA  . TYR B 2 59  ? 180.249 173.648 140.274 1.00 54.57  ? 59  TYR H CA  1 
ATOM   4682 C  C   . TYR B 2 59  ? 180.586 173.500 138.797 1.00 54.57  ? 59  TYR H C   1 
ATOM   4683 O  O   . TYR B 2 59  ? 179.773 173.813 137.922 1.00 54.57  ? 59  TYR H O   1 
ATOM   4684 C  CB  . TYR B 2 59  ? 179.702 172.325 140.811 1.00 54.57  ? 59  TYR H CB  1 
ATOM   4685 C  CG  . TYR B 2 59  ? 179.412 172.335 142.293 1.00 54.57  ? 59  TYR H CG  1 
ATOM   4686 C  CD1 . TYR B 2 59  ? 180.440 172.247 143.221 1.00 54.57  ? 59  TYR H CD1 1 
ATOM   4687 C  CD2 . TYR B 2 59  ? 178.110 172.425 142.763 1.00 54.57  ? 59  TYR H CD2 1 
ATOM   4688 C  CE1 . TYR B 2 59  ? 180.180 172.253 144.577 1.00 54.57  ? 59  TYR H CE1 1 
ATOM   4689 C  CE2 . TYR B 2 59  ? 177.839 172.432 144.117 1.00 54.57  ? 59  TYR H CE2 1 
ATOM   4690 C  CZ  . TYR B 2 59  ? 178.878 172.346 145.019 1.00 54.57  ? 59  TYR H CZ  1 
ATOM   4691 O  OH  . TYR B 2 59  ? 178.616 172.353 146.369 1.00 54.57  ? 59  TYR H OH  1 
ATOM   4692 N  N   . TYR B 2 60  ? 181.795 173.017 138.529 1.00 53.13  ? 60  TYR H N   1 
ATOM   4693 C  CA  . TYR B 2 60  ? 182.287 172.819 137.175 1.00 53.13  ? 60  TYR H CA  1 
ATOM   4694 C  C   . TYR B 2 60  ? 182.931 171.446 137.062 1.00 53.13  ? 60  TYR H C   1 
ATOM   4695 O  O   . TYR B 2 60  ? 183.375 170.863 138.054 1.00 53.13  ? 60  TYR H O   1 
ATOM   4696 C  CB  . TYR B 2 60  ? 183.311 173.886 136.781 1.00 53.13  ? 60  TYR H CB  1 
ATOM   4697 C  CG  . TYR B 2 60  ? 182.762 175.287 136.721 1.00 53.13  ? 60  TYR H CG  1 
ATOM   4698 C  CD1 . TYR B 2 60  ? 181.757 175.620 135.830 1.00 53.13  ? 60  TYR H CD1 1 
ATOM   4699 C  CD2 . TYR B 2 60  ? 183.256 176.277 137.556 1.00 53.13  ? 60  TYR H CD2 1 
ATOM   4700 C  CE1 . TYR B 2 60  ? 181.258 176.902 135.771 1.00 53.13  ? 60  TYR H CE1 1 
ATOM   4701 C  CE2 . TYR B 2 60  ? 182.763 177.560 137.505 1.00 53.13  ? 60  TYR H CE2 1 
ATOM   4702 C  CZ  . TYR B 2 60  ? 181.766 177.867 136.611 1.00 53.13  ? 60  TYR H CZ  1 
ATOM   4703 O  OH  . TYR B 2 60  ? 181.272 179.146 136.566 1.00 53.13  ? 60  TYR H OH  1 
ATOM   4704 N  N   . SER B 2 61  ? 182.981 170.934 135.839 1.00 55.17  ? 61  SER H N   1 
ATOM   4705 C  CA  . SER B 2 61  ? 183.704 169.701 135.582 1.00 55.17  ? 61  SER H CA  1 
ATOM   4706 C  C   . SER B 2 61  ? 185.196 169.991 135.451 1.00 55.17  ? 61  SER H C   1 
ATOM   4707 O  O   . SER B 2 61  ? 185.622 171.132 135.264 1.00 55.17  ? 61  SER H O   1 
ATOM   4708 C  CB  . SER B 2 61  ? 183.172 169.010 134.327 1.00 55.17  ? 61  SER H CB  1 
ATOM   4709 O  OG  . SER B 2 61  ? 183.498 169.742 133.161 1.00 55.17  ? 61  SER H OG  1 
ATOM   4710 N  N   . ASP B 2 62  ? 185.999 168.929 135.553 1.00 64.89  ? 62  ASP H N   1 
ATOM   4711 C  CA  . ASP B 2 62  ? 187.450 169.067 135.530 1.00 64.89  ? 62  ASP H CA  1 
ATOM   4712 C  C   . ASP B 2 62  ? 187.995 169.450 134.160 1.00 64.89  ? 62  ASP H C   1 
ATOM   4713 O  O   . ASP B 2 62  ? 189.155 169.865 134.071 1.00 64.89  ? 62  ASP H O   1 
ATOM   4714 C  CB  . ASP B 2 62  ? 188.106 167.765 135.994 1.00 64.89  ? 62  ASP H CB  1 
ATOM   4715 C  CG  . ASP B 2 62  ? 187.824 167.458 137.451 1.00 64.89  ? 62  ASP H CG  1 
ATOM   4716 O  OD1 . ASP B 2 62  ? 187.593 168.408 138.228 1.00 64.89  ? 62  ASP H OD1 1 
ATOM   4717 O  OD2 . ASP B 2 62  ? 187.835 166.266 137.822 1.00 64.89  ? 62  ASP H OD2 1 
ATOM   4718 N  N   . THR B 2 63  ? 187.198 169.327 133.099 1.00 61.94  ? 63  THR H N   1 
ATOM   4719 C  CA  . THR B 2 63  ? 187.669 169.622 131.753 1.00 61.94  ? 63  THR H CA  1 
ATOM   4720 C  C   . THR B 2 63  ? 187.410 171.059 131.323 1.00 61.94  ? 63  THR H C   1 
ATOM   4721 O  O   . THR B 2 63  ? 188.076 171.541 130.400 1.00 61.94  ? 63  THR H O   1 
ATOM   4722 C  CB  . THR B 2 63  ? 187.017 168.673 130.743 1.00 61.94  ? 63  THR H CB  1 
ATOM   4723 O  OG1 . THR B 2 63  ? 185.595 168.855 130.760 1.00 61.94  ? 63  THR H OG1 1 
ATOM   4724 C  CG2 . THR B 2 63  ? 187.341 167.227 131.085 1.00 61.94  ? 63  THR H CG2 1 
ATOM   4725 N  N   . VAL B 2 64  ? 186.464 171.753 131.955 1.00 58.62  ? 64  VAL H N   1 
ATOM   4726 C  CA  . VAL B 2 64  ? 186.129 173.124 131.590 1.00 58.62  ? 64  VAL H CA  1 
ATOM   4727 C  C   . VAL B 2 64  ? 186.278 174.095 132.747 1.00 58.62  ? 64  VAL H C   1 
ATOM   4728 O  O   . VAL B 2 64  ? 185.877 175.255 132.616 1.00 58.62  ? 64  VAL H O   1 
ATOM   4729 C  CB  . VAL B 2 64  ? 184.706 173.225 131.005 1.00 58.62  ? 64  VAL H CB  1 
ATOM   4730 C  CG1 . VAL B 2 64  ? 184.573 172.371 129.756 1.00 58.62  ? 64  VAL H CG1 1 
ATOM   4731 C  CG2 . VAL B 2 64  ? 183.679 172.833 132.050 1.00 58.62  ? 64  VAL H CG2 1 
ATOM   4732 N  N   . THR B 2 65  ? 186.828 173.662 133.879 1.00 61.73  ? 65  THR H N   1 
ATOM   4733 C  CA  . THR B 2 65  ? 186.983 174.558 135.016 1.00 61.73  ? 65  THR H CA  1 
ATOM   4734 C  C   . THR B 2 65  ? 188.019 175.636 134.717 1.00 61.73  ? 65  THR H C   1 
ATOM   4735 O  O   . THR B 2 65  ? 188.998 175.407 134.000 1.00 61.73  ? 65  THR H O   1 
ATOM   4736 C  CB  . THR B 2 65  ? 187.357 173.769 136.277 1.00 61.73  ? 65  THR H CB  1 
ATOM   4737 O  OG1 . THR B 2 65  ? 187.400 174.652 137.406 1.00 61.73  ? 65  THR H OG1 1 
ATOM   4738 C  CG2 . THR B 2 65  ? 188.693 173.045 136.124 1.00 61.73  ? 65  THR H CG2 1 
ATOM   4739 N  N   . GLY B 2 66  ? 187.767 176.834 135.228 1.00 61.76  ? 66  GLY H N   1 
ATOM   4740 C  CA  . GLY B 2 66  ? 188.626 177.983 135.004 1.00 61.76  ? 66  GLY H CA  1 
ATOM   4741 C  C   . GLY B 2 66  ? 188.319 178.772 133.746 1.00 61.76  ? 66  GLY H C   1 
ATOM   4742 O  O   . GLY B 2 66  ? 188.296 180.004 133.778 1.00 61.76  ? 66  GLY H O   1 
ATOM   4743 N  N   . ARG B 2 67  ? 188.081 178.079 132.632 1.00 62.02  ? 67  ARG H N   1 
ATOM   4744 C  CA  . ARG B 2 67  ? 187.803 178.740 131.365 1.00 62.02  ? 67  ARG H CA  1 
ATOM   4745 C  C   . ARG B 2 67  ? 186.325 179.019 131.141 1.00 62.02  ? 67  ARG H C   1 
ATOM   4746 O  O   . ARG B 2 67  ? 185.988 179.823 130.266 1.00 62.02  ? 67  ARG H O   1 
ATOM   4747 C  CB  . ARG B 2 67  ? 188.324 177.894 130.196 1.00 62.02  ? 67  ARG H CB  1 
ATOM   4748 C  CG  . ARG B 2 67  ? 189.641 177.193 130.464 1.00 62.02  ? 67  ARG H CG  1 
ATOM   4749 C  CD  . ARG B 2 67  ? 189.960 176.191 129.365 1.00 62.02  ? 67  ARG H CD  1 
ATOM   4750 N  NE  . ARG B 2 67  ? 189.079 175.030 129.394 1.00 62.02  ? 67  ARG H NE  1 
ATOM   4751 C  CZ  . ARG B 2 67  ? 188.294 174.662 128.390 1.00 62.02  ? 67  ARG H CZ  1 
ATOM   4752 N  NH1 . ARG B 2 67  ? 188.245 175.350 127.262 1.00 62.02  ? 67  ARG H NH1 1 
ATOM   4753 N  NH2 . ARG B 2 67  ? 187.544 173.571 128.520 1.00 62.02  ? 67  ARG H NH2 1 
ATOM   4754 N  N   . PHE B 2 68  ? 185.444 178.377 131.901 1.00 59.41  ? 68  PHE H N   1 
ATOM   4755 C  CA  . PHE B 2 68  ? 184.003 178.487 131.716 1.00 59.41  ? 68  PHE H CA  1 
ATOM   4756 C  C   . PHE B 2 68  ? 183.397 179.175 132.928 1.00 59.41  ? 68  PHE H C   1 
ATOM   4757 O  O   . PHE B 2 68  ? 183.731 178.836 134.068 1.00 59.41  ? 68  PHE H O   1 
ATOM   4758 C  CB  . PHE B 2 68  ? 183.361 177.108 131.535 1.00 59.41  ? 68  PHE H CB  1 
ATOM   4759 C  CG  . PHE B 2 68  ? 183.440 176.559 130.133 1.00 59.41  ? 68  PHE H CG  1 
ATOM   4760 C  CD1 . PHE B 2 68  ? 184.588 176.688 129.369 1.00 59.41  ? 68  PHE H CD1 1 
ATOM   4761 C  CD2 . PHE B 2 68  ? 182.361 175.885 129.592 1.00 59.41  ? 68  PHE H CD2 1 
ATOM   4762 C  CE1 . PHE B 2 68  ? 184.650 176.171 128.090 1.00 59.41  ? 68  PHE H CE1 1 
ATOM   4763 C  CE2 . PHE B 2 68  ? 182.418 175.361 128.318 1.00 59.41  ? 68  PHE H CE2 1 
ATOM   4764 C  CZ  . PHE B 2 68  ? 183.564 175.507 127.565 1.00 59.41  ? 68  PHE H CZ  1 
ATOM   4765 N  N   . THR B 2 69  ? 182.509 180.133 132.686 1.00 55.79  ? 69  THR H N   1 
ATOM   4766 C  CA  . THR B 2 69  ? 181.749 180.770 133.750 1.00 55.79  ? 69  THR H CA  1 
ATOM   4767 C  C   . THR B 2 69  ? 180.267 180.760 133.399 1.00 55.79  ? 69  THR H C   1 
ATOM   4768 O  O   . THR B 2 69  ? 179.889 180.913 132.233 1.00 55.79  ? 69  THR H O   1 
ATOM   4769 C  CB  . THR B 2 69  ? 182.249 182.202 134.030 1.00 55.79  ? 69  THR H CB  1 
ATOM   4770 O  OG1 . THR B 2 69  ? 181.515 182.765 135.125 1.00 55.79  ? 69  THR H OG1 1 
ATOM   4771 C  CG2 . THR B 2 69  ? 182.130 183.101 132.807 1.00 55.79  ? 69  THR H CG2 1 
ATOM   4772 N  N   . ILE B 2 70  ? 179.433 180.537 134.410 1.00 51.39  ? 70  ILE H N   1 
ATOM   4773 C  CA  . ILE B 2 70  ? 177.992 180.421 134.236 1.00 51.39  ? 70  ILE H CA  1 
ATOM   4774 C  C   . ILE B 2 70  ? 177.319 181.496 135.079 1.00 51.39  ? 70  ILE H C   1 
ATOM   4775 O  O   . ILE B 2 70  ? 177.634 181.657 136.264 1.00 51.39  ? 70  ILE H O   1 
ATOM   4776 C  CB  . ILE B 2 70  ? 177.489 179.008 134.597 1.00 51.39  ? 70  ILE H CB  1 
ATOM   4777 C  CG1 . ILE B 2 70  ? 175.963 178.945 134.601 1.00 51.39  ? 70  ILE H CG1 1 
ATOM   4778 C  CG2 . ILE B 2 70  ? 178.066 178.526 135.918 1.00 51.39  ? 70  ILE H CG2 1 
ATOM   4779 C  CD1 . ILE B 2 70  ? 175.422 177.539 134.692 1.00 51.39  ? 70  ILE H CD1 1 
ATOM   4780 N  N   . SER B 2 71  ? 176.425 182.252 134.459 1.00 52.75  ? 71  SER H N   1 
ATOM   4781 C  CA  . SER B 2 71  ? 175.718 183.338 135.115 1.00 52.75  ? 71  SER H CA  1 
ATOM   4782 C  C   . SER B 2 71  ? 174.267 182.934 135.339 1.00 52.75  ? 71  SER H C   1 
ATOM   4783 O  O   . SER B 2 71  ? 173.857 181.810 135.047 1.00 52.75  ? 71  SER H O   1 
ATOM   4784 C  CB  . SER B 2 71  ? 175.806 184.624 134.289 1.00 52.75  ? 71  SER H CB  1 
ATOM   4785 O  OG  . SER B 2 71  ? 177.127 184.848 133.832 1.00 52.75  ? 71  SER H OG  1 
ATOM   4786 N  N   . ARG B 2 72  ? 173.489 183.874 135.867 1.00 53.55  ? 72  ARG H N   1 
ATOM   4787 C  CA  . ARG B 2 72  ? 172.074 183.652 136.110 1.00 53.55  ? 72  ARG H CA  1 
ATOM   4788 C  C   . ARG B 2 72  ? 171.380 185.001 136.191 1.00 53.55  ? 72  ARG H C   1 
ATOM   4789 O  O   . ARG B 2 72  ? 172.014 186.034 136.415 1.00 53.55  ? 72  ARG H O   1 
ATOM   4790 C  CB  . ARG B 2 72  ? 171.842 182.857 137.398 1.00 53.55  ? 72  ARG H CB  1 
ATOM   4791 C  CG  . ARG B 2 72  ? 170.705 181.861 137.332 1.00 53.55  ? 72  ARG H CG  1 
ATOM   4792 C  CD  . ARG B 2 72  ? 170.665 181.030 138.599 1.00 53.55  ? 72  ARG H CD  1 
ATOM   4793 N  NE  . ARG B 2 72  ? 169.917 179.793 138.424 1.00 53.55  ? 72  ARG H NE  1 
ATOM   4794 C  CZ  . ARG B 2 72  ? 168.612 179.678 138.617 1.00 53.55  ? 72  ARG H CZ  1 
ATOM   4795 N  NH1 . ARG B 2 72  ? 167.878 180.709 138.997 1.00 53.55  ? 72  ARG H NH1 1 
ATOM   4796 N  NH2 . ARG B 2 72  ? 168.030 178.498 138.429 1.00 53.55  ? 72  ARG H NH2 1 
ATOM   4797 N  N   . ASP B 2 73  ? 170.061 184.978 136.004 1.00 62.36  ? 73  ASP H N   1 
ATOM   4798 C  CA  . ASP B 2 73  ? 169.248 186.179 136.181 1.00 62.36  ? 73  ASP H CA  1 
ATOM   4799 C  C   . ASP B 2 73  ? 167.834 185.722 136.523 1.00 62.36  ? 73  ASP H C   1 
ATOM   4800 O  O   . ASP B 2 73  ? 167.077 185.315 135.637 1.00 62.36  ? 73  ASP H O   1 
ATOM   4801 C  CB  . ASP B 2 73  ? 169.272 187.058 134.939 1.00 62.36  ? 73  ASP H CB  1 
ATOM   4802 C  CG  . ASP B 2 73  ? 168.982 188.510 135.253 1.00 62.36  ? 73  ASP H CG  1 
ATOM   4803 O  OD1 . ASP B 2 73  ? 168.559 188.798 136.392 1.00 62.36  ? 73  ASP H OD1 1 
ATOM   4804 O  OD2 . ASP B 2 73  ? 169.195 189.365 134.371 1.00 62.36  ? 73  ASP H OD2 1 
ATOM   4805 N  N   . ASN B 2 74  ? 167.489 185.797 137.807 1.00 62.85  ? 74  ASN H N   1 
ATOM   4806 C  CA  . ASN B 2 74  ? 166.186 185.355 138.281 1.00 62.85  ? 74  ASN H CA  1 
ATOM   4807 C  C   . ASN B 2 74  ? 165.069 186.336 137.953 1.00 62.85  ? 74  ASN H C   1 
ATOM   4808 O  O   . ASN B 2 74  ? 163.895 185.987 138.119 1.00 62.85  ? 74  ASN H O   1 
ATOM   4809 C  CB  . ASN B 2 74  ? 166.240 185.125 139.792 1.00 62.85  ? 74  ASN H CB  1 
ATOM   4810 C  CG  . ASN B 2 74  ? 167.156 183.980 140.172 1.00 62.85  ? 74  ASN H CG  1 
ATOM   4811 O  OD1 . ASN B 2 74  ? 167.204 182.958 139.491 1.00 62.85  ? 74  ASN H OD1 1 
ATOM   4812 N  ND2 . ASN B 2 74  ? 167.897 184.151 141.259 1.00 62.85  ? 74  ASN H ND2 1 
ATOM   4813 N  N   . ALA B 2 75  ? 165.399 187.544 137.496 1.00 67.98  ? 75  ALA H N   1 
ATOM   4814 C  CA  . ALA B 2 75  ? 164.379 188.550 137.222 1.00 67.98  ? 75  ALA H CA  1 
ATOM   4815 C  C   . ALA B 2 75  ? 163.719 188.321 135.867 1.00 67.98  ? 75  ALA H C   1 
ATOM   4816 O  O   . ALA B 2 75  ? 162.490 188.251 135.766 1.00 67.98  ? 75  ALA H O   1 
ATOM   4817 C  CB  . ALA B 2 75  ? 164.994 189.951 137.292 1.00 67.98  ? 75  ALA H CB  1 
ATOM   4818 N  N   . ARG B 2 76  ? 164.522 188.201 134.812 1.00 66.12  ? 76  ARG H N   1 
ATOM   4819 C  CA  . ARG B 2 76  ? 164.009 188.005 133.464 1.00 66.12  ? 76  ARG H CA  1 
ATOM   4820 C  C   . ARG B 2 76  ? 163.892 186.534 133.087 1.00 66.12  ? 76  ARG H C   1 
ATOM   4821 O  O   . ARG B 2 76  ? 163.545 186.234 131.939 1.00 66.12  ? 76  ARG H O   1 
ATOM   4822 C  CB  . ARG B 2 76  ? 164.896 188.731 132.450 1.00 66.12  ? 76  ARG H CB  1 
ATOM   4823 C  CG  . ARG B 2 76  ? 166.382 188.534 132.675 1.00 66.12  ? 76  ARG H CG  1 
ATOM   4824 C  CD  . ARG B 2 76  ? 167.199 189.476 131.810 1.00 66.12  ? 76  ARG H CD  1 
ATOM   4825 N  NE  . ARG B 2 76  ? 166.762 190.860 131.949 1.00 66.12  ? 76  ARG H NE  1 
ATOM   4826 C  CZ  . ARG B 2 76  ? 167.422 191.904 131.469 1.00 66.12  ? 76  ARG H CZ  1 
ATOM   4827 N  NH1 . ARG B 2 76  ? 168.559 191.759 130.809 1.00 66.12  ? 76  ARG H NH1 1 
ATOM   4828 N  NH2 . ARG B 2 76  ? 166.930 193.125 131.657 1.00 66.12  ? 76  ARG H NH2 1 
ATOM   4829 N  N   . ASN B 2 77  ? 164.181 185.627 134.028 1.00 63.58  ? 77  ASN H N   1 
ATOM   4830 C  CA  . ASN B 2 77  ? 164.094 184.175 133.837 1.00 63.58  ? 77  ASN H CA  1 
ATOM   4831 C  C   . ASN B 2 77  ? 164.979 183.712 132.680 1.00 63.58  ? 77  ASN H C   1 
ATOM   4832 O  O   . ASN B 2 77  ? 164.521 183.076 131.729 1.00 63.58  ? 77  ASN H O   1 
ATOM   4833 C  CB  . ASN B 2 77  ? 162.644 183.725 133.635 1.00 63.58  ? 77  ASN H CB  1 
ATOM   4834 C  CG  . ASN B 2 77  ? 161.775 184.009 134.839 1.00 63.58  ? 77  ASN H CG  1 
ATOM   4835 O  OD1 . ASN B 2 77  ? 162.212 183.876 135.981 1.00 63.58  ? 77  ASN H OD1 1 
ATOM   4836 N  ND2 . ASN B 2 77  ? 160.533 184.402 134.591 1.00 63.58  ? 77  ASN H ND2 1 
ATOM   4837 N  N   . ILE B 2 78  ? 166.267 184.042 132.767 1.00 57.25  ? 78  ILE H N   1 
ATOM   4838 C  CA  . ILE B 2 78  ? 167.221 183.725 131.716 1.00 57.25  ? 78  ILE H CA  1 
ATOM   4839 C  C   . ILE B 2 78  ? 168.456 183.101 132.357 1.00 57.25  ? 78  ILE H C   1 
ATOM   4840 O  O   . ILE B 2 78  ? 168.705 183.242 133.556 1.00 57.25  ? 78  ILE H O   1 
ATOM   4841 C  CB  . ILE B 2 78  ? 167.586 184.974 130.875 1.00 57.25  ? 78  ILE H CB  1 
ATOM   4842 C  CG1 . ILE B 2 78  ? 167.959 184.588 129.443 1.00 57.25  ? 78  ILE H CG1 1 
ATOM   4843 C  CG2 . ILE B 2 78  ? 168.716 185.758 131.514 1.00 57.25  ? 78  ILE H CG2 1 
ATOM   4844 C  CD1 . ILE B 2 78  ? 167.989 185.757 128.482 1.00 57.25  ? 78  ILE H CD1 1 
ATOM   4845 N  N   . LEU B 2 79  ? 169.213 182.372 131.541 1.00 51.39  ? 79  LEU H N   1 
ATOM   4846 C  CA  . LEU B 2 79  ? 170.423 181.688 131.969 1.00 51.39  ? 79  LEU H CA  1 
ATOM   4847 C  C   . LEU B 2 79  ? 171.526 181.965 130.959 1.00 51.39  ? 79  LEU H C   1 
ATOM   4848 O  O   . LEU B 2 79  ? 171.256 182.208 129.781 1.00 51.39  ? 79  LEU H O   1 
ATOM   4849 C  CB  . LEU B 2 79  ? 170.186 180.181 132.100 1.00 51.39  ? 79  LEU H CB  1 
ATOM   4850 C  CG  . LEU B 2 79  ? 171.232 179.288 132.761 1.00 51.39  ? 79  LEU H CG  1 
ATOM   4851 C  CD1 . LEU B 2 79  ? 171.325 179.566 134.245 1.00 51.39  ? 79  LEU H CD1 1 
ATOM   4852 C  CD2 . LEU B 2 79  ? 170.889 177.840 132.502 1.00 51.39  ? 79  LEU H CD2 1 
ATOM   4853 N  N   . HIS B 2 80  ? 172.771 181.933 131.423 1.00 50.64  ? 80  HIS H N   1 
ATOM   4854 C  CA  . HIS B 2 80  ? 173.904 182.268 130.576 1.00 50.64  ? 80  HIS H CA  1 
ATOM   4855 C  C   . HIS B 2 80  ? 175.037 181.281 130.808 1.00 50.64  ? 80  HIS H C   1 
ATOM   4856 O  O   . HIS B 2 80  ? 175.112 180.622 131.846 1.00 50.64  ? 80  HIS H O   1 
ATOM   4857 C  CB  . HIS B 2 80  ? 174.393 183.695 130.836 1.00 50.64  ? 80  HIS H CB  1 
ATOM   4858 C  CG  . HIS B 2 80  ? 173.407 184.752 130.450 1.00 50.64  ? 80  HIS H CG  1 
ATOM   4859 N  ND1 . HIS B 2 80  ? 173.302 185.238 129.165 1.00 50.64  ? 80  HIS H ND1 1 
ATOM   4860 C  CD2 . HIS B 2 80  ? 172.481 185.417 131.180 1.00 50.64  ? 80  HIS H CD2 1 
ATOM   4861 C  CE1 . HIS B 2 80  ? 172.355 186.158 129.120 1.00 50.64  ? 80  HIS H CE1 1 
ATOM   4862 N  NE2 . HIS B 2 80  ? 171.842 186.286 130.330 1.00 50.64  ? 80  HIS H NE2 1 
ATOM   4863 N  N   . LEU B 2 81  ? 175.923 181.190 129.819 1.00 48.73  ? 81  LEU H N   1 
ATOM   4864 C  CA  . LEU B 2 81  ? 177.140 180.393 129.939 1.00 48.73  ? 81  LEU H CA  1 
ATOM   4865 C  C   . LEU B 2 81  ? 178.200 181.041 129.061 1.00 48.73  ? 81  LEU H C   1 
ATOM   4866 O  O   . LEU B 2 81  ? 178.129 180.945 127.833 1.00 48.73  ? 81  LEU H O   1 
ATOM   4867 C  CB  . LEU B 2 81  ? 176.899 178.942 129.533 1.00 48.73  ? 81  LEU H CB  1 
ATOM   4868 C  CG  . LEU B 2 81  ? 178.115 178.014 129.552 1.00 48.73  ? 81  LEU H CG  1 
ATOM   4869 C  CD1 . LEU B 2 81  ? 178.603 177.802 130.969 1.00 48.73  ? 81  LEU H CD1 1 
ATOM   4870 C  CD2 . LEU B 2 81  ? 177.778 176.683 128.914 1.00 48.73  ? 81  LEU H CD2 1 
ATOM   4871 N  N   . GLU B 2 82  ? 179.172 181.699 129.685 1.00 55.58  ? 82  GLU H N   1 
ATOM   4872 C  CA  . GLU B 2 82  ? 180.229 182.402 128.971 1.00 55.58  ? 82  GLU H CA  1 
ATOM   4873 C  C   . GLU B 2 82  ? 181.516 181.595 129.051 1.00 55.58  ? 82  GLU H C   1 
ATOM   4874 O  O   . GLU B 2 82  ? 181.915 181.159 130.136 1.00 55.58  ? 82  GLU H O   1 
ATOM   4875 C  CB  . GLU B 2 82  ? 180.442 183.801 129.552 1.00 55.58  ? 82  GLU H CB  1 
ATOM   4876 C  CG  . GLU B 2 82  ? 181.652 184.531 128.990 1.00 55.58  ? 82  GLU H CG  1 
ATOM   4877 C  CD  . GLU B 2 82  ? 182.216 185.556 129.953 1.00 55.58  ? 82  GLU H CD  1 
ATOM   4878 O  OE1 . GLU B 2 82  ? 181.549 186.587 130.182 1.00 55.58  ? 82  GLU H OE1 1 
ATOM   4879 O  OE2 . GLU B 2 82  ? 183.327 185.332 130.480 1.00 55.58  ? 82  GLU H OE2 1 
ATOM   4880 N  N   . MET B 2 83  ? 182.161 181.397 127.905 1.00 59.78  ? 83  MET H N   1 
ATOM   4881 C  CA  . MET B 2 83  ? 183.358 180.578 127.810 1.00 59.78  ? 83  MET H CA  1 
ATOM   4882 C  C   . MET B 2 83  ? 184.518 181.403 127.274 1.00 59.78  ? 83  MET H C   1 
ATOM   4883 O  O   . MET B 2 83  ? 184.321 182.393 126.566 1.00 59.78  ? 83  MET H O   1 
ATOM   4884 C  CB  . MET B 2 83  ? 183.127 179.370 126.900 1.00 59.78  ? 83  MET H CB  1 
ATOM   4885 C  CG  . MET B 2 83  ? 181.826 178.648 127.162 1.00 59.78  ? 83  MET H CG  1 
ATOM   4886 S  SD  . MET B 2 83  ? 181.335 177.620 125.775 1.00 59.78  ? 83  MET H SD  1 
ATOM   4887 C  CE  . MET B 2 83  ? 180.137 178.698 125.012 1.00 59.78  ? 83  MET H CE  1 
ATOM   4888 N  N   . SER B 2 84  ? 185.731 180.983 127.623 1.00 65.53  ? 84  SER H N   1 
ATOM   4889 C  CA  . SER B 2 84  ? 186.944 181.621 127.136 1.00 65.53  ? 84  SER H CA  1 
ATOM   4890 C  C   . SER B 2 84  ? 187.954 180.549 126.761 1.00 65.53  ? 84  SER H C   1 
ATOM   4891 O  O   . SER B 2 84  ? 187.934 179.442 127.308 1.00 65.53  ? 84  SER H O   1 
ATOM   4892 C  CB  . SER B 2 84  ? 187.546 182.569 128.181 1.00 65.53  ? 84  SER H CB  1 
ATOM   4893 O  OG  . SER B 2 84  ? 188.808 183.057 127.760 1.00 65.53  ? 84  SER H OG  1 
ATOM   4894 N  N   . SER B 2 85  ? 188.836 180.900 125.819 1.00 70.21  ? 85  SER H N   1 
ATOM   4895 C  CA  . SER B 2 85  ? 189.902 180.030 125.312 1.00 70.21  ? 85  SER H CA  1 
ATOM   4896 C  C   . SER B 2 85  ? 189.337 178.714 124.771 1.00 70.21  ? 85  SER H C   1 
ATOM   4897 O  O   . SER B 2 85  ? 189.710 177.619 125.197 1.00 70.21  ? 85  SER H O   1 
ATOM   4898 C  CB  . SER B 2 85  ? 190.970 179.779 126.383 1.00 70.21  ? 85  SER H CB  1 
ATOM   4899 O  OG  . SER B 2 85  ? 190.575 178.740 127.261 1.00 70.21  ? 85  SER H OG  1 
ATOM   4900 N  N   . LEU B 2 86  ? 188.414 178.846 123.822 1.00 70.57  ? 86  LEU H N   1 
ATOM   4901 C  CA  . LEU B 2 86  ? 187.801 177.679 123.204 1.00 70.57  ? 86  LEU H CA  1 
ATOM   4902 C  C   . LEU B 2 86  ? 188.798 176.978 122.292 1.00 70.57  ? 86  LEU H C   1 
ATOM   4903 O  O   . LEU B 2 86  ? 189.400 177.603 121.414 1.00 70.57  ? 86  LEU H O   1 
ATOM   4904 C  CB  . LEU B 2 86  ? 186.563 178.091 122.411 1.00 70.57  ? 86  LEU H CB  1 
ATOM   4905 C  CG  . LEU B 2 86  ? 185.350 178.529 123.229 1.00 70.57  ? 86  LEU H CG  1 
ATOM   4906 C  CD1 . LEU B 2 86  ? 184.301 179.157 122.333 1.00 70.57  ? 86  LEU H CD1 1 
ATOM   4907 C  CD2 . LEU B 2 86  ? 184.769 177.343 123.976 1.00 70.57  ? 86  LEU H CD2 1 
ATOM   4908 N  N   . ARG B 2 87  ? 188.976 175.681 122.503 1.00 66.85  ? 87  ARG H N   1 
ATOM   4909 C  CA  . ARG B 2 87  ? 189.819 174.863 121.651 1.00 66.85  ? 87  ARG H CA  1 
ATOM   4910 C  C   . ARG B 2 87  ? 188.937 174.044 120.711 1.00 66.85  ? 87  ARG H C   1 
ATOM   4911 O  O   . ARG B 2 87  ? 187.725 174.249 120.621 1.00 66.85  ? 87  ARG H O   1 
ATOM   4912 C  CB  . ARG B 2 87  ? 190.736 173.981 122.501 1.00 66.85  ? 87  ARG H CB  1 
ATOM   4913 C  CG  . ARG B 2 87  ? 190.074 173.384 123.730 1.00 66.85  ? 87  ARG H CG  1 
ATOM   4914 C  CD  . ARG B 2 87  ? 190.959 172.321 124.359 1.00 66.85  ? 87  ARG H CD  1 
ATOM   4915 N  NE  . ARG B 2 87  ? 192.019 172.898 125.175 1.00 66.85  ? 87  ARG H NE  1 
ATOM   4916 C  CZ  . ARG B 2 87  ? 191.883 173.234 126.450 1.00 66.85  ? 87  ARG H CZ  1 
ATOM   4917 N  NH1 . ARG B 2 87  ? 190.743 173.053 127.094 1.00 66.85  ? 87  ARG H NH1 1 
ATOM   4918 N  NH2 . ARG B 2 87  ? 192.919 173.762 127.096 1.00 66.85  ? 87  ARG H NH2 1 
ATOM   4919 N  N   . SER B 2 88  ? 189.548 173.111 119.988 1.00 65.80  ? 88  SER H N   1 
ATOM   4920 C  CA  . SER B 2 88  ? 188.787 172.220 119.124 1.00 65.80  ? 88  SER H CA  1 
ATOM   4921 C  C   . SER B 2 88  ? 188.202 171.032 119.873 1.00 65.80  ? 88  SER H C   1 
ATOM   4922 O  O   . SER B 2 88  ? 187.486 170.230 119.264 1.00 65.80  ? 88  SER H O   1 
ATOM   4923 C  CB  . SER B 2 88  ? 189.668 171.722 117.976 1.00 65.80  ? 88  SER H CB  1 
ATOM   4924 O  OG  . SER B 2 88  ? 189.021 170.690 117.254 1.00 65.80  ? 88  SER H OG  1 
ATOM   4925 N  N   . GLU B 2 89  ? 188.486 170.898 121.167 1.00 66.24  ? 89  GLU H N   1 
ATOM   4926 C  CA  . GLU B 2 89  ? 188.015 169.757 121.939 1.00 66.24  ? 89  GLU H CA  1 
ATOM   4927 C  C   . GLU B 2 89  ? 186.645 169.984 122.561 1.00 66.24  ? 89  GLU H C   1 
ATOM   4928 O  O   . GLU B 2 89  ? 185.920 169.013 122.806 1.00 66.24  ? 89  GLU H O   1 
ATOM   4929 C  CB  . GLU B 2 89  ? 189.024 169.413 123.041 1.00 66.24  ? 89  GLU H CB  1 
ATOM   4930 C  CG  . GLU B 2 89  ? 188.965 167.971 123.546 1.00 66.24  ? 89  GLU H CG  1 
ATOM   4931 C  CD  . GLU B 2 89  ? 189.722 166.984 122.665 1.00 66.24  ? 89  GLU H CD  1 
ATOM   4932 O  OE1 . GLU B 2 89  ? 190.172 167.366 121.564 1.00 66.24  ? 89  GLU H OE1 1 
ATOM   4933 O  OE2 . GLU B 2 89  ? 189.869 165.816 123.083 1.00 66.24  ? 89  GLU H OE2 1 
ATOM   4934 N  N   . ASP B 2 90  ? 186.267 171.233 122.823 1.00 62.66  ? 90  ASP H N   1 
ATOM   4935 C  CA  . ASP B 2 90  ? 184.978 171.533 123.445 1.00 62.66  ? 90  ASP H CA  1 
ATOM   4936 C  C   . ASP B 2 90  ? 183.963 172.063 122.440 1.00 62.66  ? 90  ASP H C   1 
ATOM   4937 O  O   . ASP B 2 90  ? 183.156 172.938 122.765 1.00 62.66  ? 90  ASP H O   1 
ATOM   4938 C  CB  . ASP B 2 90  ? 185.148 172.509 124.607 1.00 62.66  ? 90  ASP H CB  1 
ATOM   4939 C  CG  . ASP B 2 90  ? 185.996 173.710 124.252 1.00 62.66  ? 90  ASP H CG  1 
ATOM   4940 O  OD1 . ASP B 2 90  ? 186.441 173.805 123.094 1.00 62.66  ? 90  ASP H OD1 1 
ATOM   4941 O  OD2 . ASP B 2 90  ? 186.221 174.560 125.140 1.00 62.66  ? 90  ASP H OD2 1 
ATOM   4942 N  N   . THR B 2 91  ? 183.986 171.556 121.210 1.00 59.18  ? 91  THR H N   1 
ATOM   4943 C  CA  . THR B 2 91  ? 182.903 171.788 120.266 1.00 59.18  ? 91  THR H CA  1 
ATOM   4944 C  C   . THR B 2 91  ? 181.847 170.702 120.444 1.00 59.18  ? 91  THR H C   1 
ATOM   4945 O  O   . THR B 2 91  ? 182.173 169.515 120.564 1.00 59.18  ? 91  THR H O   1 
ATOM   4946 C  CB  . THR B 2 91  ? 183.422 171.854 118.821 1.00 59.18  ? 91  THR H CB  1 
ATOM   4947 O  OG1 . THR B 2 91  ? 182.344 172.173 117.933 1.00 59.18  ? 91  THR H OG1 1 
ATOM   4948 C  CG2 . THR B 2 91  ? 184.126 170.570 118.370 1.00 59.18  ? 91  THR H CG2 1 
ATOM   4949 N  N   . ALA B 2 92  ? 180.591 171.117 120.516 1.00 51.61  ? 92  ALA H N   1 
ATOM   4950 C  CA  . ALA B 2 92  ? 179.500 170.239 120.928 1.00 51.61  ? 92  ALA H CA  1 
ATOM   4951 C  C   . ALA B 2 92  ? 178.184 170.931 120.600 1.00 51.61  ? 92  ALA H C   1 
ATOM   4952 O  O   . ALA B 2 92  ? 178.158 171.970 119.929 1.00 51.61  ? 92  ALA H O   1 
ATOM   4953 C  CB  . ALA B 2 92  ? 179.593 169.905 122.417 1.00 51.61  ? 92  ALA H CB  1 
ATOM   4954 N  N   . MET B 2 93  ? 177.086 170.350 121.075 1.00 48.41  ? 93  MET H N   1 
ATOM   4955 C  CA  . MET B 2 93  ? 175.778 170.993 121.062 1.00 48.41  ? 93  MET H CA  1 
ATOM   4956 C  C   . MET B 2 93  ? 175.294 171.048 122.502 1.00 48.41  ? 93  MET H C   1 
ATOM   4957 O  O   . MET B 2 93  ? 175.087 170.005 123.129 1.00 48.41  ? 93  MET H O   1 
ATOM   4958 C  CB  . MET B 2 93  ? 174.792 170.245 120.167 1.00 48.41  ? 93  MET H CB  1 
ATOM   4959 C  CG  . MET B 2 93  ? 173.429 170.904 120.083 1.00 48.41  ? 93  MET H CG  1 
ATOM   4960 S  SD  . MET B 2 93  ? 172.335 170.112 118.894 1.00 48.41  ? 93  MET H SD  1 
ATOM   4961 C  CE  . MET B 2 93  ? 172.002 168.567 119.724 1.00 48.41  ? 93  MET H CE  1 
ATOM   4962 N  N   . TYR B 2 94  ? 175.121 172.257 123.027 1.00 44.17  ? 94  TYR H N   1 
ATOM   4963 C  CA  . TYR B 2 94  ? 174.906 172.437 124.456 1.00 44.17  ? 94  TYR H CA  1 
ATOM   4964 C  C   . TYR B 2 94  ? 173.418 172.445 124.782 1.00 44.17  ? 94  TYR H C   1 
ATOM   4965 O  O   . TYR B 2 94  ? 172.639 173.170 124.159 1.00 44.17  ? 94  TYR H O   1 
ATOM   4966 C  CB  . TYR B 2 94  ? 175.559 173.735 124.933 1.00 44.17  ? 94  TYR H CB  1 
ATOM   4967 C  CG  . TYR B 2 94  ? 177.070 173.676 124.996 1.00 44.17  ? 94  TYR H CG  1 
ATOM   4968 C  CD1 . TYR B 2 94  ? 177.838 173.760 123.843 1.00 44.17  ? 94  TYR H CD1 1 
ATOM   4969 C  CD2 . TYR B 2 94  ? 177.727 173.533 126.208 1.00 44.17  ? 94  TYR H CD2 1 
ATOM   4970 C  CE1 . TYR B 2 94  ? 179.212 173.703 123.894 1.00 44.17  ? 94  TYR H CE1 1 
ATOM   4971 C  CE2 . TYR B 2 94  ? 179.105 173.476 126.268 1.00 44.17  ? 94  TYR H CE2 1 
ATOM   4972 C  CZ  . TYR B 2 94  ? 179.841 173.560 125.107 1.00 44.17  ? 94  TYR H CZ  1 
ATOM   4973 O  OH  . TYR B 2 94  ? 181.213 173.503 125.158 1.00 44.17  ? 94  TYR H OH  1 
ATOM   4974 N  N   . TYR B 2 95  ? 173.033 171.639 125.765 1.00 40.24  ? 95  TYR H N   1 
ATOM   4975 C  CA  . TYR B 2 95  ? 171.667 171.581 126.258 1.00 40.24  ? 95  TYR H CA  1 
ATOM   4976 C  C   . TYR B 2 95  ? 171.523 172.434 127.509 1.00 40.24  ? 95  TYR H C   1 
ATOM   4977 O  O   . TYR B 2 95  ? 172.497 172.732 128.201 1.00 40.24  ? 95  TYR H O   1 
ATOM   4978 C  CB  . TYR B 2 95  ? 171.262 170.141 126.577 1.00 40.24  ? 95  TYR H CB  1 
ATOM   4979 C  CG  . TYR B 2 95  ? 171.066 169.260 125.372 1.00 40.24  ? 95  TYR H CG  1 
ATOM   4980 C  CD1 . TYR B 2 95  ? 170.025 169.484 124.486 1.00 40.24  ? 95  TYR H CD1 1 
ATOM   4981 C  CD2 . TYR B 2 95  ? 171.929 168.209 125.117 1.00 40.24  ? 95  TYR H CD2 1 
ATOM   4982 C  CE1 . TYR B 2 95  ? 169.846 168.675 123.383 1.00 40.24  ? 95  TYR H CE1 1 
ATOM   4983 C  CE2 . TYR B 2 95  ? 171.760 167.400 124.020 1.00 40.24  ? 95  TYR H CE2 1 
ATOM   4984 C  CZ  . TYR B 2 95  ? 170.720 167.635 123.155 1.00 40.24  ? 95  TYR H CZ  1 
ATOM   4985 O  OH  . TYR B 2 95  ? 170.558 166.817 122.062 1.00 40.24  ? 95  TYR H OH  1 
ATOM   4986 N  N   . CYS B 2 96  ? 170.285 172.813 127.801 1.00 42.24  ? 96  CYS H N   1 
ATOM   4987 C  CA  . CYS B 2 96  ? 169.951 173.570 129.005 1.00 42.24  ? 96  CYS H CA  1 
ATOM   4988 C  C   . CYS B 2 96  ? 169.061 172.683 129.871 1.00 42.24  ? 96  CYS H C   1 
ATOM   4989 O  O   . CYS B 2 96  ? 167.834 172.770 129.821 1.00 42.24  ? 96  CYS H O   1 
ATOM   4990 C  CB  . CYS B 2 96  ? 169.265 174.882 128.648 1.00 42.24  ? 96  CYS H CB  1 
ATOM   4991 S  SG  . CYS B 2 96  ? 168.778 175.911 130.048 1.00 42.24  ? 96  CYS H SG  1 
ATOM   4992 N  N   . ALA B 2 97  ? 169.691 171.833 130.673 1.00 40.38  ? 97  ALA H N   1 
ATOM   4993 C  CA  . ALA B 2 97  ? 168.960 170.935 131.550 1.00 40.38  ? 97  ALA H CA  1 
ATOM   4994 C  C   . ALA B 2 97  ? 168.502 171.671 132.803 1.00 40.38  ? 97  ALA H C   1 
ATOM   4995 O  O   . ALA B 2 97  ? 169.019 172.732 133.154 1.00 40.38  ? 97  ALA H O   1 
ATOM   4996 C  CB  . ALA B 2 97  ? 169.824 169.738 131.933 1.00 40.38  ? 97  ALA H CB  1 
ATOM   4997 N  N   . ARG B 2 98  ? 167.520 171.088 133.485 1.00 43.19  ? 98  ARG H N   1 
ATOM   4998 C  CA  . ARG B 2 98  ? 166.985 171.646 134.724 1.00 43.19  ? 98  ARG H CA  1 
ATOM   4999 C  C   . ARG B 2 98  ? 167.008 170.561 135.787 1.00 43.19  ? 98  ARG H C   1 
ATOM   5000 O  O   . ARG B 2 98  ? 166.243 169.596 135.708 1.00 43.19  ? 98  ARG H O   1 
ATOM   5001 C  CB  . ARG B 2 98  ? 165.567 172.179 134.531 1.00 43.19  ? 98  ARG H CB  1 
ATOM   5002 C  CG  . ARG B 2 98  ? 164.867 172.526 135.834 1.00 43.19  ? 98  ARG H CG  1 
ATOM   5003 C  CD  . ARG B 2 98  ? 163.500 173.126 135.586 1.00 43.19  ? 98  ARG H CD  1 
ATOM   5004 N  NE  . ARG B 2 98  ? 162.556 172.808 136.650 1.00 43.19  ? 98  ARG H NE  1 
ATOM   5005 C  CZ  . ARG B 2 98  ? 161.792 171.724 136.674 1.00 43.19  ? 98  ARG H CZ  1 
ATOM   5006 N  NH1 . ARG B 2 98  ? 161.826 170.834 135.699 1.00 43.19  ? 98  ARG H NH1 1 
ATOM   5007 N  NH2 . ARG B 2 98  ? 160.969 171.534 137.700 1.00 43.19  ? 98  ARG H NH2 1 
ATOM   5008 N  N   . GLY B 2 99  ? 167.889 170.702 136.769 1.00 44.85  ? 99  GLY H N   1 
ATOM   5009 C  CA  . GLY B 2 99  ? 167.896 169.763 137.869 1.00 44.85  ? 99  GLY H CA  1 
ATOM   5010 C  C   . GLY B 2 99  ? 168.017 170.438 139.215 1.00 44.85  ? 99  GLY H C   1 
ATOM   5011 O  O   . GLY B 2 99  ? 169.030 171.080 139.500 1.00 44.85  ? 99  GLY H O   1 
ATOM   5012 N  N   . GLU B 2 100 ? 166.999 170.288 140.059 1.00 51.09  ? 100 GLU H N   1 
ATOM   5013 C  CA  . GLU B 2 100 ? 167.015 170.848 141.402 1.00 51.09  ? 100 GLU H CA  1 
ATOM   5014 C  C   . GLU B 2 100 ? 167.086 169.773 142.472 1.00 51.09  ? 100 GLU H C   1 
ATOM   5015 O  O   . GLU B 2 100 ? 167.977 169.805 143.326 1.00 51.09  ? 100 GLU H O   1 
ATOM   5016 C  CB  . GLU B 2 100 ? 165.774 171.728 141.628 1.00 51.09  ? 100 GLU H CB  1 
ATOM   5017 C  CG  . GLU B 2 100 ? 165.480 172.106 143.090 1.00 51.09  ? 100 GLU H CG  1 
ATOM   5018 C  CD  . GLU B 2 100 ? 166.466 173.103 143.712 1.00 51.09  ? 100 GLU H CD  1 
ATOM   5019 O  OE1 . GLU B 2 100 ? 167.454 173.506 143.063 1.00 51.09  ? 100 GLU H OE1 1 
ATOM   5020 O  OE2 . GLU B 2 100 ? 166.240 173.495 144.876 1.00 51.09  ? 100 GLU H OE2 1 
ATOM   5021 N  N   . VAL B 2 101 ? 166.169 168.813 142.442 1.00 46.87  ? 101 VAL H N   1 
ATOM   5022 C  CA  . VAL B 2 101 ? 166.206 167.688 143.368 1.00 46.87  ? 101 VAL H CA  1 
ATOM   5023 C  C   . VAL B 2 101 ? 167.222 166.683 142.843 1.00 46.87  ? 101 VAL H C   1 
ATOM   5024 O  O   . VAL B 2 101 ? 167.101 166.198 141.714 1.00 46.87  ? 101 VAL H O   1 
ATOM   5025 C  CB  . VAL B 2 101 ? 164.819 167.050 143.519 1.00 46.87  ? 101 VAL H CB  1 
ATOM   5026 C  CG1 . VAL B 2 101 ? 164.914 165.736 144.272 1.00 46.87  ? 101 VAL H CG1 1 
ATOM   5027 C  CG2 . VAL B 2 101 ? 163.868 168.006 144.219 1.00 46.87  ? 101 VAL H CG2 1 
ATOM   5028 N  N   . ARG B 2 102 ? 168.227 166.370 143.661 1.00 43.78  ? 102 ARG H N   1 
ATOM   5029 C  CA  . ARG B 2 102 ? 169.269 165.446 143.234 1.00 43.78  ? 102 ARG H CA  1 
ATOM   5030 C  C   . ARG B 2 102 ? 168.796 164.000 143.182 1.00 43.78  ? 102 ARG H C   1 
ATOM   5031 O  O   . ARG B 2 102 ? 169.505 163.156 142.628 1.00 43.78  ? 102 ARG H O   1 
ATOM   5032 C  CB  . ARG B 2 102 ? 170.486 165.561 144.147 1.00 43.78  ? 102 ARG H CB  1 
ATOM   5033 C  CG  . ARG B 2 102 ? 171.304 166.815 143.915 1.00 43.78  ? 102 ARG H CG  1 
ATOM   5034 C  CD  . ARG B 2 102 ? 172.777 166.559 144.159 1.00 43.78  ? 102 ARG H CD  1 
ATOM   5035 N  NE  . ARG B 2 102 ? 173.527 167.800 144.303 1.00 43.78  ? 102 ARG H NE  1 
ATOM   5036 C  CZ  . ARG B 2 102 ? 174.117 168.189 145.423 1.00 43.78  ? 102 ARG H CZ  1 
ATOM   5037 N  NH1 . ARG B 2 102 ? 174.056 167.459 146.524 1.00 43.78  ? 102 ARG H NH1 1 
ATOM   5038 N  NH2 . ARG B 2 102 ? 174.785 169.338 145.439 1.00 43.78  ? 102 ARG H NH2 1 
ATOM   5039 N  N   . GLN B 2 103 ? 167.635 163.693 143.746 1.00 46.51  ? 103 GLN H N   1 
ATOM   5040 C  CA  . GLN B 2 103 ? 167.022 162.384 143.597 1.00 46.51  ? 103 GLN H CA  1 
ATOM   5041 C  C   . GLN B 2 103 ? 166.053 162.334 142.425 1.00 46.51  ? 103 GLN H C   1 
ATOM   5042 O  O   . GLN B 2 103 ? 165.416 161.300 142.202 1.00 46.51  ? 103 GLN H O   1 
ATOM   5043 C  CB  . GLN B 2 103 ? 166.307 161.987 144.891 1.00 46.51  ? 103 GLN H CB  1 
ATOM   5044 C  CG  . GLN B 2 103 ? 167.234 161.434 145.963 1.00 46.51  ? 103 GLN H CG  1 
ATOM   5045 C  CD  . GLN B 2 103 ? 168.042 162.511 146.658 1.00 46.51  ? 103 GLN H CD  1 
ATOM   5046 O  OE1 . GLN B 2 103 ? 167.550 163.188 147.557 1.00 46.51  ? 103 GLN H OE1 1 
ATOM   5047 N  NE2 . GLN B 2 103 ? 169.289 162.678 146.238 1.00 46.51  ? 103 GLN H NE2 1 
ATOM   5048 N  N   . ARG B 2 104 ? 165.930 163.428 141.675 1.00 46.46  ? 104 ARG H N   1 
ATOM   5049 C  CA  . ARG B 2 104 ? 165.034 163.516 140.532 1.00 46.46  ? 104 ARG H CA  1 
ATOM   5050 C  C   . ARG B 2 104 ? 165.761 163.593 139.202 1.00 46.46  ? 104 ARG H C   1 
ATOM   5051 O  O   . ARG B 2 104 ? 165.263 163.059 138.210 1.00 46.46  ? 104 ARG H O   1 
ATOM   5052 C  CB  . ARG B 2 104 ? 164.124 164.743 140.670 1.00 46.46  ? 104 ARG H CB  1 
ATOM   5053 C  CG  . ARG B 2 104 ? 162.790 164.467 141.344 1.00 46.46  ? 104 ARG H CG  1 
ATOM   5054 C  CD  . ARG B 2 104 ? 162.008 163.393 140.620 1.00 46.46  ? 104 ARG H CD  1 
ATOM   5055 N  NE  . ARG B 2 104 ? 161.800 163.737 139.219 1.00 46.46  ? 104 ARG H NE  1 
ATOM   5056 C  CZ  . ARG B 2 104 ? 160.760 164.425 138.767 1.00 46.46  ? 104 ARG H CZ  1 
ATOM   5057 N  NH1 . ARG B 2 104 ? 159.810 164.855 139.581 1.00 46.46  ? 104 ARG H NH1 1 
ATOM   5058 N  NH2 . ARG B 2 104 ? 160.672 164.688 137.467 1.00 46.46  ? 104 ARG H NH2 1 
ATOM   5059 N  N   . GLY B 2 105 ? 166.922 164.240 139.157 1.00 41.05  ? 105 GLY H N   1 
ATOM   5060 C  CA  . GLY B 2 105 ? 167.688 164.345 137.934 1.00 41.05  ? 105 GLY H CA  1 
ATOM   5061 C  C   . GLY B 2 105 ? 167.278 165.523 137.078 1.00 41.05  ? 105 GLY H C   1 
ATOM   5062 O  O   . GLY B 2 105 ? 166.400 166.322 137.415 1.00 41.05  ? 105 GLY H O   1 
ATOM   5063 N  N   . PHE B 2 106 ? 167.943 165.627 135.928 1.00 38.79  ? 106 PHE H N   1 
ATOM   5064 C  CA  . PHE B 2 106 ? 167.655 166.671 134.947 1.00 38.79  ? 106 PHE H CA  1 
ATOM   5065 C  C   . PHE B 2 106 ? 166.346 166.305 134.254 1.00 38.79  ? 106 PHE H C   1 
ATOM   5066 O  O   . PHE B 2 106 ? 166.317 165.659 133.205 1.00 38.79  ? 106 PHE H O   1 
ATOM   5067 C  CB  . PHE B 2 106 ? 168.794 166.800 133.944 1.00 38.79  ? 106 PHE H CB  1 
ATOM   5068 C  CG  . PHE B 2 106 ? 170.098 167.241 134.547 1.00 38.79  ? 106 PHE H CG  1 
ATOM   5069 C  CD1 . PHE B 2 106 ? 170.128 168.007 135.697 1.00 38.79  ? 106 PHE H CD1 1 
ATOM   5070 C  CD2 . PHE B 2 106 ? 171.297 166.892 133.953 1.00 38.79  ? 106 PHE H CD2 1 
ATOM   5071 C  CE1 . PHE B 2 106 ? 171.328 168.410 136.245 1.00 38.79  ? 106 PHE H CE1 1 
ATOM   5072 C  CE2 . PHE B 2 106 ? 172.497 167.295 134.496 1.00 38.79  ? 106 PHE H CE2 1 
ATOM   5073 C  CZ  . PHE B 2 106 ? 172.513 168.051 135.643 1.00 38.79  ? 106 PHE H CZ  1 
ATOM   5074 N  N   . ASP B 2 107 ? 165.235 166.723 134.865 1.00 43.03  ? 107 ASP H N   1 
ATOM   5075 C  CA  . ASP B 2 107 ? 163.935 166.231 134.419 1.00 43.03  ? 107 ASP H CA  1 
ATOM   5076 C  C   . ASP B 2 107 ? 163.475 166.909 133.132 1.00 43.03  ? 107 ASP H C   1 
ATOM   5077 O  O   . ASP B 2 107 ? 162.893 166.257 132.259 1.00 43.03  ? 107 ASP H O   1 
ATOM   5078 C  CB  . ASP B 2 107 ? 162.898 166.389 135.534 1.00 43.03  ? 107 ASP H CB  1 
ATOM   5079 C  CG  . ASP B 2 107 ? 162.785 167.809 136.045 1.00 43.03  ? 107 ASP H CG  1 
ATOM   5080 O  OD1 . ASP B 2 107 ? 163.544 168.684 135.587 1.00 43.03  ? 107 ASP H OD1 1 
ATOM   5081 O  OD2 . ASP B 2 107 ? 161.929 168.054 136.921 1.00 43.03  ? 107 ASP H OD2 1 
ATOM   5082 N  N   . TYR B 2 108 ? 163.724 168.207 132.989 1.00 43.90  ? 108 TYR H N   1 
ATOM   5083 C  CA  . TYR B 2 108 ? 163.283 168.960 131.821 1.00 43.90  ? 108 TYR H CA  1 
ATOM   5084 C  C   . TYR B 2 108 ? 164.503 169.488 131.085 1.00 43.90  ? 108 TYR H C   1 
ATOM   5085 O  O   . TYR B 2 108 ? 165.274 170.275 131.643 1.00 43.90  ? 108 TYR H O   1 
ATOM   5086 C  CB  . TYR B 2 108 ? 162.359 170.109 132.224 1.00 43.90  ? 108 TYR H CB  1 
ATOM   5087 C  CG  . TYR B 2 108 ? 160.923 169.694 132.453 1.00 43.90  ? 108 TYR H CG  1 
ATOM   5088 C  CD1 . TYR B 2 108 ? 160.502 168.398 132.188 1.00 43.90  ? 108 TYR H CD1 1 
ATOM   5089 C  CD2 . TYR B 2 108 ? 159.991 170.598 132.941 1.00 43.90  ? 108 TYR H CD2 1 
ATOM   5090 C  CE1 . TYR B 2 108 ? 159.192 168.015 132.397 1.00 43.90  ? 108 TYR H CE1 1 
ATOM   5091 C  CE2 . TYR B 2 108 ? 158.679 170.225 133.155 1.00 43.90  ? 108 TYR H CE2 1 
ATOM   5092 C  CZ  . TYR B 2 108 ? 158.285 168.933 132.881 1.00 43.90  ? 108 TYR H CZ  1 
ATOM   5093 O  OH  . TYR B 2 108 ? 156.979 168.555 133.091 1.00 43.90  ? 108 TYR H OH  1 
ATOM   5094 N  N   . TRP B 2 109 ? 164.669 169.069 129.837 1.00 38.62  ? 109 TRP H N   1 
ATOM   5095 C  CA  . TRP B 2 109 ? 165.808 169.452 129.018 1.00 38.62  ? 109 TRP H CA  1 
ATOM   5096 C  C   . TRP B 2 109 ? 165.383 170.498 127.995 1.00 38.62  ? 109 TRP H C   1 
ATOM   5097 O  O   . TRP B 2 109 ? 164.200 170.808 127.837 1.00 38.62  ? 109 TRP H O   1 
ATOM   5098 C  CB  . TRP B 2 109 ? 166.416 168.230 128.332 1.00 38.62  ? 109 TRP H CB  1 
ATOM   5099 C  CG  . TRP B 2 109 ? 167.127 167.309 129.267 1.00 38.62  ? 109 TRP H CG  1 
ATOM   5100 C  CD1 . TRP B 2 109 ? 166.573 166.570 130.265 1.00 38.62  ? 109 TRP H CD1 1 
ATOM   5101 C  CD2 . TRP B 2 109 ? 168.527 167.016 129.280 1.00 38.62  ? 109 TRP H CD2 1 
ATOM   5102 N  NE1 . TRP B 2 109 ? 167.541 165.839 130.906 1.00 38.62  ? 109 TRP H NE1 1 
ATOM   5103 C  CE2 . TRP B 2 109 ? 168.750 166.095 130.318 1.00 38.62  ? 109 TRP H CE2 1 
ATOM   5104 C  CE3 . TRP B 2 109 ? 169.614 167.444 128.516 1.00 38.62  ? 109 TRP H CE3 1 
ATOM   5105 C  CZ2 . TRP B 2 109 ? 170.014 165.598 130.613 1.00 38.62  ? 109 TRP H CZ2 1 
ATOM   5106 C  CZ3 . TRP B 2 109 ? 170.866 166.948 128.809 1.00 38.62  ? 109 TRP H CZ3 1 
ATOM   5107 C  CH2 . TRP B 2 109 ? 171.057 166.035 129.848 1.00 38.62  ? 109 TRP H CH2 1 
ATOM   5108 N  N   . GLY B 2 110 ? 166.366 171.041 127.295 1.00 41.34  ? 110 GLY H N   1 
ATOM   5109 C  CA  . GLY B 2 110 ? 166.159 172.106 126.342 1.00 41.34  ? 110 GLY H CA  1 
ATOM   5110 C  C   . GLY B 2 110 ? 166.039 171.603 124.922 1.00 41.34  ? 110 GLY H C   1 
ATOM   5111 O  O   . GLY B 2 110 ? 165.630 170.464 124.672 1.00 41.34  ? 110 GLY H O   1 
ATOM   5112 N  N   . GLN B 2 111 ? 166.395 172.466 123.973 1.00 47.28  ? 111 GLN H N   1 
ATOM   5113 C  CA  . GLN B 2 111 ? 166.358 172.133 122.555 1.00 47.28  ? 111 GLN H CA  1 
ATOM   5114 C  C   . GLN B 2 111 ? 167.741 171.836 121.993 1.00 47.28  ? 111 GLN H C   1 
ATOM   5115 O  O   . GLN B 2 111 ? 167.919 170.846 121.278 1.00 47.28  ? 111 GLN H O   1 
ATOM   5116 C  CB  . GLN B 2 111 ? 165.705 173.272 121.762 1.00 47.28  ? 111 GLN H CB  1 
ATOM   5117 N  N   . GLY B 2 112 ? 168.727 172.672 122.303 1.00 49.58  ? 112 GLY H N   1 
ATOM   5118 C  CA  . GLY B 2 112 ? 170.079 172.439 121.837 1.00 49.58  ? 112 GLY H CA  1 
ATOM   5119 C  C   . GLY B 2 112 ? 170.559 173.468 120.837 1.00 49.58  ? 112 GLY H C   1 
ATOM   5120 O  O   . GLY B 2 112 ? 169.910 173.694 119.812 1.00 49.58  ? 112 GLY H O   1 
ATOM   5121 N  N   . THR B 2 113 ? 171.689 174.107 121.125 1.00 49.11  ? 113 THR H N   1 
ATOM   5122 C  CA  . THR B 2 113 ? 172.304 175.065 120.217 1.00 49.11  ? 113 THR H CA  1 
ATOM   5123 C  C   . THR B 2 113 ? 173.644 174.519 119.747 1.00 49.11  ? 113 THR H C   1 
ATOM   5124 O  O   . THR B 2 113 ? 174.525 174.237 120.567 1.00 49.11  ? 113 THR H O   1 
ATOM   5125 C  CB  . THR B 2 113 ? 172.493 176.419 120.893 1.00 49.11  ? 113 THR H CB  1 
ATOM   5126 O  OG1 . THR B 2 113 ? 173.385 176.274 122.005 1.00 49.11  ? 113 THR H OG1 1 
ATOM   5127 C  CG2 . THR B 2 113 ? 171.164 176.954 121.377 1.00 49.11  ? 113 THR H CG2 1 
ATOM   5128 N  N   . THR B 2 114 ? 173.798 174.382 118.434 1.00 53.91  ? 114 THR H N   1 
ATOM   5129 C  CA  . THR B 2 114 ? 175.025 173.832 117.877 1.00 53.91  ? 114 THR H CA  1 
ATOM   5130 C  C   . THR B 2 114 ? 176.160 174.837 118.012 1.00 53.91  ? 114 THR H C   1 
ATOM   5131 O  O   . THR B 2 114 ? 175.995 176.021 117.707 1.00 53.91  ? 114 THR H O   1 
ATOM   5132 C  CB  . THR B 2 114 ? 174.823 173.465 116.410 1.00 53.91  ? 114 THR H CB  1 
ATOM   5133 O  OG1 . THR B 2 114 ? 174.508 174.645 115.662 1.00 53.91  ? 114 THR H OG1 1 
ATOM   5134 C  CG2 . THR B 2 114 ? 173.687 172.466 116.267 1.00 53.91  ? 114 THR H CG2 1 
ATOM   5135 N  N   . LEU B 2 115 ? 177.312 174.364 118.475 1.00 57.23  ? 115 LEU H N   1 
ATOM   5136 C  CA  . LEU B 2 115 ? 178.497 175.193 118.629 1.00 57.23  ? 115 LEU H CA  1 
ATOM   5137 C  C   . LEU B 2 115 ? 179.649 174.543 117.877 1.00 57.23  ? 115 LEU H C   1 
ATOM   5138 O  O   . LEU B 2 115 ? 179.925 173.354 118.065 1.00 57.23  ? 115 LEU H O   1 
ATOM   5139 C  CB  . LEU B 2 115 ? 178.843 175.378 120.108 1.00 57.23  ? 115 LEU H CB  1 
ATOM   5140 C  CG  . LEU B 2 115 ? 179.858 176.459 120.471 1.00 57.23  ? 115 LEU H CG  1 
ATOM   5141 C  CD1 . LEU B 2 115 ? 179.408 177.145 121.734 1.00 57.23  ? 115 LEU H CD1 1 
ATOM   5142 C  CD2 . LEU B 2 115 ? 181.233 175.869 120.676 1.00 57.23  ? 115 LEU H CD2 1 
ATOM   5143 N  N   . THR B 2 116 ? 180.315 175.322 117.030 1.00 66.85  ? 116 THR H N   1 
ATOM   5144 C  CA  . THR B 2 116 ? 181.396 174.820 116.195 1.00 66.85  ? 116 THR H CA  1 
ATOM   5145 C  C   . THR B 2 116 ? 182.628 175.688 116.388 1.00 66.85  ? 116 THR H C   1 
ATOM   5146 O  O   . THR B 2 116 ? 182.558 176.910 116.230 1.00 66.85  ? 116 THR H O   1 
ATOM   5147 C  CB  . THR B 2 116 ? 180.990 174.805 114.718 1.00 66.85  ? 116 THR H CB  1 
ATOM   5148 O  OG1 . THR B 2 116 ? 179.812 174.007 114.553 1.00 66.85  ? 116 THR H OG1 1 
ATOM   5149 C  CG2 . THR B 2 116 ? 182.107 174.226 113.865 1.00 66.85  ? 116 THR H CG2 1 
ATOM   5150 N  N   . VAL B 2 117 ? 183.749 175.060 116.729 1.00 69.91  ? 117 VAL H N   1 
ATOM   5151 C  CA  . VAL B 2 117 ? 185.033 175.742 116.838 1.00 69.91  ? 117 VAL H CA  1 
ATOM   5152 C  C   . VAL B 2 117 ? 185.956 175.166 115.777 1.00 69.91  ? 117 VAL H C   1 
ATOM   5153 O  O   . VAL B 2 117 ? 186.234 173.961 115.779 1.00 69.91  ? 117 VAL H O   1 
ATOM   5154 C  CB  . VAL B 2 117 ? 185.654 175.590 118.234 1.00 69.91  ? 117 VAL H CB  1 
ATOM   5155 C  CG1 . VAL B 2 117 ? 186.891 176.457 118.344 1.00 69.91  ? 117 VAL H CG1 1 
ATOM   5156 C  CG2 . VAL B 2 117 ? 184.654 175.960 119.303 1.00 69.91  ? 117 VAL H CG2 1 
ATOM   5157 N  N   . SER B 2 118 ? 186.435 176.024 114.881 1.00 77.36  ? 118 SER H N   1 
ATOM   5158 C  CA  . SER B 2 118 ? 187.349 175.595 113.834 1.00 77.36  ? 118 SER H CA  1 
ATOM   5159 C  C   . SER B 2 118 ? 188.106 176.804 113.312 1.00 77.36  ? 118 SER H C   1 
ATOM   5160 O  O   . SER B 2 118 ? 187.663 177.947 113.452 1.00 77.36  ? 118 SER H O   1 
ATOM   5161 C  CB  . SER B 2 118 ? 186.609 174.906 112.685 1.00 77.36  ? 118 SER H CB  1 
ATOM   5162 O  OG  . SER B 2 118 ? 185.862 175.855 111.949 1.00 77.36  ? 118 SER H OG  1 
ATOM   5163 N  N   . SER B 2 119 ? 189.250 176.531 112.693 1.00 81.31  ? 119 SER H N   1 
ATOM   5164 C  CA  . SER B 2 119 ? 190.032 177.550 112.008 1.00 81.31  ? 119 SER H CA  1 
ATOM   5165 C  C   . SER B 2 119 ? 189.576 177.766 110.572 1.00 81.31  ? 119 SER H C   1 
ATOM   5166 O  O   . SER B 2 119 ? 190.150 178.607 109.874 1.00 81.31  ? 119 SER H O   1 
ATOM   5167 C  CB  . SER B 2 119 ? 191.518 177.179 112.026 1.00 81.31  ? 119 SER H CB  1 
ATOM   5168 O  OG  . SER B 2 119 ? 191.989 177.020 113.352 1.00 81.31  ? 119 SER H OG  1 
ATOM   5169 N  N   . ALA B 2 120 ? 188.567 177.027 110.117 1.00 82.45  ? 120 ALA H N   1 
ATOM   5170 C  CA  . ALA B 2 120 ? 188.076 177.147 108.755 1.00 82.45  ? 120 ALA H CA  1 
ATOM   5171 C  C   . ALA B 2 120 ? 187.184 178.378 108.619 1.00 82.45  ? 120 ALA H C   1 
ATOM   5172 O  O   . ALA B 2 120 ? 186.870 179.068 109.592 1.00 82.45  ? 120 ALA H O   1 
ATOM   5173 C  CB  . ALA B 2 120 ? 187.332 175.878 108.348 1.00 82.45  ? 120 ALA H CB  1 
ATOM   5174 N  N   . LYS B 2 121 ? 186.762 178.651 107.389 1.00 88.78  ? 121 LYS H N   1 
ATOM   5175 C  CA  . LYS B 2 121 ? 185.987 179.837 107.066 1.00 88.78  ? 121 LYS H CA  1 
ATOM   5176 C  C   . LYS B 2 121 ? 184.592 179.444 106.600 1.00 88.78  ? 121 LYS H C   1 
ATOM   5177 O  O   . LYS B 2 121 ? 184.364 178.333 106.114 1.00 88.78  ? 121 LYS H O   1 
ATOM   5178 C  CB  . LYS B 2 121 ? 186.682 180.668 105.982 1.00 88.78  ? 121 LYS H CB  1 
ATOM   5179 C  CG  . LYS B 2 121 ? 187.997 181.281 106.423 1.00 88.78  ? 121 LYS H CG  1 
ATOM   5180 C  CD  . LYS B 2 121 ? 188.558 182.202 105.355 1.00 88.78  ? 121 LYS H CD  1 
ATOM   5181 C  CE  . LYS B 2 121 ? 189.120 181.405 104.189 1.00 88.78  ? 121 LYS H CE  1 
ATOM   5182 N  NZ  . LYS B 2 121 ? 189.776 182.282 103.181 1.00 88.78  ? 121 LYS H NZ  1 
ATOM   5183 N  N   . THR B 2 122 ? 183.656 180.376 106.757 1.00 90.22  ? 122 THR H N   1 
ATOM   5184 C  CA  . THR B 2 122 ? 182.289 180.153 106.306 1.00 90.22  ? 122 THR H CA  1 
ATOM   5185 C  C   . THR B 2 122 ? 182.216 180.264 104.789 1.00 90.22  ? 122 THR H C   1 
ATOM   5186 O  O   . THR B 2 122 ? 182.694 181.240 104.203 1.00 90.22  ? 122 THR H O   1 
ATOM   5187 C  CB  . THR B 2 122 ? 181.345 181.165 106.955 1.00 90.22  ? 122 THR H CB  1 
ATOM   5188 O  OG1 . THR B 2 122 ? 181.456 181.077 108.380 1.00 90.22  ? 122 THR H OG1 1 
ATOM   5189 C  CG2 . THR B 2 122 ? 179.906 180.891 106.551 1.00 90.22  ? 122 THR H CG2 1 
ATOM   5190 N  N   . THR B 2 123 ? 181.615 179.264 104.152 1.00 96.53  ? 123 THR H N   1 
ATOM   5191 C  CA  . THR B 2 123 ? 181.480 179.222 102.704 1.00 96.53  ? 123 THR H CA  1 
ATOM   5192 C  C   . THR B 2 123 ? 180.023 178.962 102.343 1.00 96.53  ? 123 THR H C   1 
ATOM   5193 O  O   . THR B 2 123 ? 179.355 178.140 102.977 1.00 96.53  ? 123 THR H O   1 
ATOM   5194 C  CB  . THR B 2 123 ? 182.387 178.139 102.101 1.00 96.53  ? 123 THR H CB  1 
ATOM   5195 O  OG1 . THR B 2 123 ? 183.717 178.294 102.611 1.00 96.53  ? 123 THR H OG1 1 
ATOM   5196 C  CG2 . THR B 2 123 ? 182.431 178.249 100.583 1.00 96.53  ? 123 THR H CG2 1 
ATOM   5197 N  N   . ALA B 2 124 ? 179.535 179.683 101.335 1.00 102.66 ? 124 ALA H N   1 
ATOM   5198 C  CA  . ALA B 2 124 ? 178.155 179.532 100.899 1.00 102.66 ? 124 ALA H CA  1 
ATOM   5199 C  C   . ALA B 2 124 ? 177.940 178.154 100.274 1.00 102.66 ? 124 ALA H C   1 
ATOM   5200 O  O   . ALA B 2 124 ? 178.835 177.631 99.602  1.00 102.66 ? 124 ALA H O   1 
ATOM   5201 C  CB  . ALA B 2 124 ? 177.794 180.625 99.892  1.00 102.66 ? 124 ALA H CB  1 
ATOM   5202 N  N   . PRO B 2 125 ? 176.777 177.538 100.486 1.00 104.79 ? 125 PRO H N   1 
ATOM   5203 C  CA  . PRO B 2 125 ? 176.538 176.204 99.922  1.00 104.79 ? 125 PRO H CA  1 
ATOM   5204 C  C   . PRO B 2 125 ? 176.339 176.252 98.416  1.00 104.79 ? 125 PRO H C   1 
ATOM   5205 O  O   . PRO B 2 125 ? 175.933 177.272 97.854  1.00 104.79 ? 125 PRO H O   1 
ATOM   5206 C  CB  . PRO B 2 125 ? 175.266 175.739 100.638 1.00 104.79 ? 125 PRO H CB  1 
ATOM   5207 C  CG  . PRO B 2 125 ? 174.566 176.990 101.005 1.00 104.79 ? 125 PRO H CG  1 
ATOM   5208 C  CD  . PRO B 2 125 ? 175.629 178.019 101.273 1.00 104.79 ? 125 PRO H CD  1 
ATOM   5209 N  N   . SER B 2 126 ? 176.637 175.132 97.766  1.00 107.52 ? 126 SER H N   1 
ATOM   5210 C  CA  . SER B 2 126 ? 176.466 174.968 96.325  1.00 107.52 ? 126 SER H CA  1 
ATOM   5211 C  C   . SER B 2 126 ? 175.500 173.809 96.103  1.00 107.52 ? 126 SER H C   1 
ATOM   5212 O  O   . SER B 2 126 ? 175.890 172.641 96.186  1.00 107.52 ? 126 SER H O   1 
ATOM   5213 C  CB  . SER B 2 126 ? 177.806 174.714 95.642  1.00 107.52 ? 126 SER H CB  1 
ATOM   5214 O  OG  . SER B 2 126 ? 178.720 175.764 95.901  1.00 107.52 ? 126 SER H OG  1 
ATOM   5215 N  N   . VAL B 2 127 ? 174.242 174.130 95.822  1.00 110.25 ? 127 VAL H N   1 
ATOM   5216 C  CA  . VAL B 2 127 ? 173.232 173.103 95.600  1.00 110.25 ? 127 VAL H CA  1 
ATOM   5217 C  C   . VAL B 2 127 ? 173.360 172.580 94.178  1.00 110.25 ? 127 VAL H C   1 
ATOM   5218 O  O   . VAL B 2 127 ? 173.282 173.346 93.210  1.00 110.25 ? 127 VAL H O   1 
ATOM   5219 C  CB  . VAL B 2 127 ? 171.824 173.655 95.868  1.00 110.25 ? 127 VAL H CB  1 
ATOM   5220 C  CG1 . VAL B 2 127 ? 170.778 172.601 95.556  1.00 110.25 ? 127 VAL H CG1 1 
ATOM   5221 C  CG2 . VAL B 2 127 ? 171.708 174.101 97.311  1.00 110.25 ? 127 VAL H CG2 1 
ATOM   5222 N  N   . TYR B 2 128 ? 173.559 171.275 94.048  1.00 113.79 ? 128 TYR H N   1 
ATOM   5223 C  CA  . TYR B 2 128 ? 173.768 170.638 92.748  1.00 113.79 ? 128 TYR H CA  1 
ATOM   5224 C  C   . TYR B 2 128 ? 172.597 169.716 92.444  1.00 113.79 ? 128 TYR H C   1 
ATOM   5225 O  O   . TYR B 2 128 ? 172.382 168.732 93.179  1.00 113.79 ? 128 TYR H O   1 
ATOM   5226 C  CB  . TYR B 2 128 ? 175.080 169.855 92.736  1.00 113.79 ? 128 TYR H CB  1 
ATOM   5227 C  CG  . TYR B 2 128 ? 176.308 170.668 92.379  1.00 113.79 ? 128 TYR H CG  1 
ATOM   5228 C  CD1 . TYR B 2 128 ? 176.373 172.029 92.653  1.00 113.79 ? 128 TYR H CD1 1 
ATOM   5229 C  CD2 . TYR B 2 128 ? 177.406 170.070 91.775  1.00 113.79 ? 128 TYR H CD2 1 
ATOM   5230 C  CE1 . TYR B 2 128 ? 177.493 172.771 92.333  1.00 113.79 ? 128 TYR H CE1 1 
ATOM   5231 C  CE2 . TYR B 2 128 ? 178.531 170.805 91.450  1.00 113.79 ? 128 TYR H CE2 1 
ATOM   5232 C  CZ  . TYR B 2 128 ? 178.569 172.154 91.731  1.00 113.79 ? 128 TYR H CZ  1 
ATOM   5233 O  OH  . TYR B 2 128 ? 179.686 172.887 91.409  1.00 113.79 ? 128 TYR H OH  1 
ATOM   5234 N  N   . PRO B 2 129 ? 171.806 169.986 91.408  1.00 118.76 ? 129 PRO H N   1 
ATOM   5235 C  CA  . PRO B 2 129 ? 170.720 169.068 91.051  1.00 118.76 ? 129 PRO H CA  1 
ATOM   5236 C  C   . PRO B 2 129 ? 171.253 167.765 90.477  1.00 118.76 ? 129 PRO H C   1 
ATOM   5237 O  O   . PRO B 2 129 ? 172.367 167.698 89.952  1.00 118.76 ? 129 PRO H O   1 
ATOM   5238 C  CB  . PRO B 2 129 ? 169.925 169.851 90.001  1.00 118.76 ? 129 PRO H CB  1 
ATOM   5239 C  CG  . PRO B 2 129 ? 170.916 170.802 89.421  1.00 118.76 ? 129 PRO H CG  1 
ATOM   5240 C  CD  . PRO B 2 129 ? 171.821 171.184 90.554  1.00 118.76 ? 129 PRO H CD  1 
ATOM   5241 N  N   . LEU B 2 130 ? 170.438 166.717 90.586  1.00 123.88 ? 130 LEU H N   1 
ATOM   5242 C  CA  . LEU B 2 130 ? 170.802 165.384 90.126  1.00 123.88 ? 130 LEU H CA  1 
ATOM   5243 C  C   . LEU B 2 130 ? 169.705 164.831 89.228  1.00 123.88 ? 130 LEU H C   1 
ATOM   5244 O  O   . LEU B 2 130 ? 168.529 164.835 89.606  1.00 123.88 ? 130 LEU H O   1 
ATOM   5245 C  CB  . LEU B 2 130 ? 171.041 164.445 91.309  1.00 123.88 ? 130 LEU H CB  1 
ATOM   5246 C  CG  . LEU B 2 130 ? 172.250 164.767 92.187  1.00 123.88 ? 130 LEU H CG  1 
ATOM   5247 C  CD1 . LEU B 2 130 ? 172.285 163.847 93.396  1.00 123.88 ? 130 LEU H CD1 1 
ATOM   5248 C  CD2 . LEU B 2 130 ? 173.537 164.664 91.384  1.00 123.88 ? 130 LEU H CD2 1 
ATOM   5249 N  N   . ALA B 2 131 ? 170.097 164.339 88.043  1.00 128.96 ? 131 ALA H N   1 
ATOM   5250 C  CA  . ALA B 2 131 ? 169.168 163.797 87.057  1.00 128.96 ? 131 ALA H CA  1 
ATOM   5251 C  C   . ALA B 2 131 ? 169.152 162.279 87.127  1.00 128.96 ? 131 ALA H C   1 
ATOM   5252 O  O   . ALA B 2 131 ? 170.200 161.667 87.379  1.00 128.96 ? 131 ALA H O   1 
ATOM   5253 C  CB  . ALA B 2 131 ? 169.560 164.245 85.652  1.00 128.96 ? 131 ALA H CB  1 
ATOM   5254 N  N   . PRO B 2 132 ? 167.997 161.635 86.915  1.00 132.99 ? 132 PRO H N   1 
ATOM   5255 C  CA  . PRO B 2 132 ? 167.947 160.166 86.967  1.00 132.99 ? 132 PRO H CA  1 
ATOM   5256 C  C   . PRO B 2 132 ? 168.564 159.506 85.744  1.00 132.99 ? 132 PRO H C   1 
ATOM   5257 O  O   . PRO B 2 132 ? 168.999 160.185 84.808  1.00 132.99 ? 132 PRO H O   1 
ATOM   5258 C  CB  . PRO B 2 132 ? 166.443 159.863 87.058  1.00 132.99 ? 132 PRO H CB  1 
ATOM   5259 C  CG  . PRO B 2 132 ? 165.777 161.175 87.359  1.00 132.99 ? 132 PRO H CG  1 
ATOM   5260 C  CD  . PRO B 2 132 ? 166.657 162.223 86.769  1.00 132.99 ? 132 PRO H CD  1 
ATOM   5261 N  N   . VAL B 2 133 ? 168.605 158.171 85.746  1.00 135.37 ? 133 VAL H N   1 
ATOM   5262 C  CA  . VAL B 2 133 ? 169.129 157.444 84.596  1.00 135.37 ? 133 VAL H CA  1 
ATOM   5263 C  C   . VAL B 2 133 ? 168.106 157.448 83.463  1.00 135.37 ? 133 VAL H C   1 
ATOM   5264 O  O   . VAL B 2 133 ? 166.927 157.778 83.642  1.00 135.37 ? 133 VAL H O   1 
ATOM   5265 C  CB  . VAL B 2 133 ? 169.518 156.007 84.982  1.00 135.37 ? 133 VAL H CB  1 
ATOM   5266 C  CG1 . VAL B 2 133 ? 170.510 156.016 86.133  1.00 135.37 ? 133 VAL H CG1 1 
ATOM   5267 C  CG2 . VAL B 2 133 ? 168.280 155.200 85.342  1.00 135.37 ? 133 VAL H CG2 1 
ATOM   5268 N  N   . CYS B 2 134 ? 168.572 157.073 82.277  1.00 136.33 ? 134 CYS H N   1 
ATOM   5269 C  CA  . CYS B 2 134 ? 167.712 157.002 81.103  1.00 136.33 ? 134 CYS H CA  1 
ATOM   5270 C  C   . CYS B 2 134 ? 167.825 155.640 80.426  1.00 136.33 ? 134 CYS H C   1 
ATOM   5271 O  O   . CYS B 2 134 ? 167.006 155.288 79.578  1.00 136.33 ? 134 CYS H O   1 
ATOM   5272 C  CB  . CYS B 2 134 ? 168.062 158.114 80.112  1.00 136.33 ? 134 CYS H CB  1 
ATOM   5273 S  SG  . CYS B 2 134 ? 169.785 158.110 79.567  1.00 136.33 ? 134 CYS H SG  1 
ATOM   5274 N  N   . GLY B 2 139 ? 163.028 152.933 85.127  1.00 151.48 ? 139 GLY H N   1 
ATOM   5275 C  CA  . GLY B 2 139 ? 162.317 151.871 85.814  1.00 151.48 ? 139 GLY H CA  1 
ATOM   5276 C  C   . GLY B 2 139 ? 160.904 152.253 86.206  1.00 151.48 ? 139 GLY H C   1 
ATOM   5277 O  O   . GLY B 2 139 ? 160.264 153.068 85.541  1.00 151.48 ? 139 GLY H O   1 
ATOM   5278 N  N   . SER B 2 140 ? 160.414 151.659 87.295  1.00 150.97 ? 140 SER H N   1 
ATOM   5279 C  CA  . SER B 2 140 ? 159.066 151.937 87.781  1.00 150.97 ? 140 SER H CA  1 
ATOM   5280 C  C   . SER B 2 140 ? 159.061 153.084 88.789  1.00 150.97 ? 140 SER H C   1 
ATOM   5281 O  O   . SER B 2 140 ? 158.360 154.083 88.601  1.00 150.97 ? 140 SER H O   1 
ATOM   5282 C  CB  . SER B 2 140 ? 158.458 150.673 88.398  1.00 150.97 ? 140 SER H CB  1 
ATOM   5283 O  OG  . SER B 2 140 ? 157.306 150.983 89.163  1.00 150.97 ? 140 SER H OG  1 
ATOM   5284 N  N   . SER B 2 141 ? 159.837 152.953 89.862  1.00 145.72 ? 141 SER H N   1 
ATOM   5285 C  CA  . SER B 2 141 ? 159.928 153.980 90.898  1.00 145.72 ? 141 SER H CA  1 
ATOM   5286 C  C   . SER B 2 141 ? 161.113 154.878 90.563  1.00 145.72 ? 141 SER H C   1 
ATOM   5287 O  O   . SER B 2 141 ? 162.256 154.592 90.920  1.00 145.72 ? 141 SER H O   1 
ATOM   5288 C  CB  . SER B 2 141 ? 160.068 153.354 92.280  1.00 145.72 ? 141 SER H CB  1 
ATOM   5289 O  OG  . SER B 2 141 ? 160.041 154.348 93.291  1.00 145.72 ? 141 SER H OG  1 
ATOM   5290 N  N   . VAL B 2 142 ? 160.833 155.975 89.868  1.00 142.71 ? 142 VAL H N   1 
ATOM   5291 C  CA  . VAL B 2 142 ? 161.875 156.915 89.474  1.00 142.71 ? 142 VAL H CA  1 
ATOM   5292 C  C   . VAL B 2 142 ? 162.216 157.803 90.662  1.00 142.71 ? 142 VAL H C   1 
ATOM   5293 O  O   . VAL B 2 142 ? 161.336 158.444 91.248  1.00 142.71 ? 142 VAL H O   1 
ATOM   5294 C  CB  . VAL B 2 142 ? 161.424 157.747 88.263  1.00 142.71 ? 142 VAL H CB  1 
ATOM   5295 C  CG1 . VAL B 2 142 ? 162.483 158.776 87.900  1.00 142.71 ? 142 VAL H CG1 1 
ATOM   5296 C  CG2 . VAL B 2 142 ? 161.129 156.838 87.079  1.00 142.71 ? 142 VAL H CG2 1 
ATOM   5297 N  N   . THR B 2 143 ? 163.497 157.847 91.018  1.00 132.62 ? 143 THR H N   1 
ATOM   5298 C  CA  . THR B 2 143 ? 163.970 158.591 92.175  1.00 132.62 ? 143 THR H CA  1 
ATOM   5299 C  C   . THR B 2 143 ? 164.752 159.824 91.737  1.00 132.62 ? 143 THR H C   1 
ATOM   5300 O  O   . THR B 2 143 ? 165.261 159.894 90.614  1.00 132.62 ? 143 THR H O   1 
ATOM   5301 C  CB  . THR B 2 143 ? 164.838 157.704 93.077  1.00 132.62 ? 143 THR H CB  1 
ATOM   5302 O  OG1 . THR B 2 143 ? 165.243 158.443 94.237  1.00 132.62 ? 143 THR H OG1 1 
ATOM   5303 C  CG2 . THR B 2 143 ? 166.061 157.194 92.332  1.00 132.62 ? 143 THR H CG2 1 
ATOM   5304 N  N   . LEU B 2 144 ? 164.826 160.806 92.633  1.00 128.98 ? 144 LEU H N   1 
ATOM   5305 C  CA  . LEU B 2 144 ? 165.480 162.075 92.357  1.00 128.98 ? 144 LEU H CA  1 
ATOM   5306 C  C   . LEU B 2 144 ? 166.383 162.449 93.524  1.00 128.98 ? 144 LEU H C   1 
ATOM   5307 O  O   . LEU B 2 144 ? 166.094 162.127 94.679  1.00 128.98 ? 144 LEU H O   1 
ATOM   5308 C  CB  . LEU B 2 144 ? 164.454 163.186 92.110  1.00 128.98 ? 144 LEU H CB  1 
ATOM   5309 C  CG  . LEU B 2 144 ? 164.924 164.383 91.284  1.00 128.98 ? 144 LEU H CG  1 
ATOM   5310 C  CD1 . LEU B 2 144 ? 165.369 163.923 89.908  1.00 128.98 ? 144 LEU H CD1 1 
ATOM   5311 C  CD2 . LEU B 2 144 ? 163.823 165.426 91.175  1.00 128.98 ? 144 LEU H CD2 1 
ATOM   5312 N  N   . GLY B 2 145 ? 167.478 163.145 93.212  1.00 122.12 ? 145 GLY H N   1 
ATOM   5313 C  CA  . GLY B 2 145 ? 168.476 163.466 94.205  1.00 122.12 ? 145 GLY H CA  1 
ATOM   5314 C  C   . GLY B 2 145 ? 168.859 164.934 94.176  1.00 122.12 ? 145 GLY H C   1 
ATOM   5315 O  O   . GLY B 2 145 ? 168.609 165.652 93.209  1.00 122.12 ? 145 GLY H O   1 
ATOM   5316 N  N   . CYS B 2 146 ? 169.486 165.364 95.272  1.00 114.95 ? 146 CYS H N   1 
ATOM   5317 C  CA  . CYS B 2 146 ? 169.901 166.755 95.451  1.00 114.95 ? 146 CYS H CA  1 
ATOM   5318 C  C   . CYS B 2 146 ? 171.046 166.762 96.458  1.00 114.95 ? 146 CYS H C   1 
ATOM   5319 O  O   . CYS B 2 146 ? 170.824 166.519 97.647  1.00 114.95 ? 146 CYS H O   1 
ATOM   5320 C  CB  . CYS B 2 146 ? 168.738 167.615 95.927  1.00 114.95 ? 146 CYS H CB  1 
ATOM   5321 S  SG  . CYS B 2 146 ? 169.130 169.358 96.185  1.00 114.95 ? 146 CYS H SG  1 
ATOM   5322 N  N   . LEU B 2 147 ? 172.257 167.040 95.985  1.00 109.01 ? 147 LEU H N   1 
ATOM   5323 C  CA  . LEU B 2 147 ? 173.422 167.067 96.856  1.00 109.01 ? 147 LEU H CA  1 
ATOM   5324 C  C   . LEU B 2 147 ? 173.933 168.493 97.016  1.00 109.01 ? 147 LEU H C   1 
ATOM   5325 O  O   . LEU B 2 147 ? 173.945 169.282 96.067  1.00 109.01 ? 147 LEU H O   1 
ATOM   5326 C  CB  . LEU B 2 147 ? 174.537 166.155 96.325  1.00 109.01 ? 147 LEU H CB  1 
ATOM   5327 C  CG  . LEU B 2 147 ? 175.247 166.340 94.975  1.00 109.01 ? 147 LEU H CG  1 
ATOM   5328 C  CD1 . LEU B 2 147 ? 176.428 167.308 95.040  1.00 109.01 ? 147 LEU H CD1 1 
ATOM   5329 C  CD2 . LEU B 2 147 ? 175.706 164.997 94.444  1.00 109.01 ? 147 LEU H CD2 1 
ATOM   5330 N  N   . VAL B 2 148 ? 174.358 168.815 98.233  1.00 101.24 ? 148 VAL H N   1 
ATOM   5331 C  CA  . VAL B 2 148 ? 174.937 170.111 98.557  1.00 101.24 ? 148 VAL H CA  1 
ATOM   5332 C  C   . VAL B 2 148 ? 176.388 169.879 98.946  1.00 101.24 ? 148 VAL H C   1 
ATOM   5333 O  O   . VAL B 2 148 ? 176.669 169.146 99.902  1.00 101.24 ? 148 VAL H O   1 
ATOM   5334 C  CB  . VAL B 2 148 ? 174.171 170.812 99.687  1.00 101.24 ? 148 VAL H CB  1 
ATOM   5335 C  CG1 . VAL B 2 148 ? 174.852 172.114 100.053 1.00 101.24 ? 148 VAL H CG1 1 
ATOM   5336 C  CG2 . VAL B 2 148 ? 172.732 171.052 99.278  1.00 101.24 ? 148 VAL H CG2 1 
ATOM   5337 N  N   . LYS B 2 149 ? 177.305 170.498 98.209  1.00 99.61  ? 149 LYS H N   1 
ATOM   5338 C  CA  . LYS B 2 149 ? 178.735 170.297 98.396  1.00 99.61  ? 149 LYS H CA  1 
ATOM   5339 C  C   . LYS B 2 149 ? 179.409 171.642 98.624  1.00 99.61  ? 149 LYS H C   1 
ATOM   5340 O  O   . LYS B 2 149 ? 179.173 172.594 97.873  1.00 99.61  ? 149 LYS H O   1 
ATOM   5341 C  CB  . LYS B 2 149 ? 179.348 169.588 97.183  1.00 99.61  ? 149 LYS H CB  1 
ATOM   5342 C  CG  . LYS B 2 149 ? 180.863 169.687 97.081  1.00 99.61  ? 149 LYS H CG  1 
ATOM   5343 C  CD  . LYS B 2 149 ? 181.542 168.811 98.119  1.00 99.61  ? 149 LYS H CD  1 
ATOM   5344 C  CE  . LYS B 2 149 ? 182.834 168.214 97.585  1.00 99.61  ? 149 LYS H CE  1 
ATOM   5345 N  NZ  . LYS B 2 149 ? 183.489 167.324 98.585  1.00 99.61  ? 149 LYS H NZ  1 
ATOM   5346 N  N   . GLY B 2 150 ? 180.239 171.718 99.662  1.00 98.72  ? 150 GLY H N   1 
ATOM   5347 C  CA  . GLY B 2 150 ? 181.021 172.911 99.915  1.00 98.72  ? 150 GLY H CA  1 
ATOM   5348 C  C   . GLY B 2 150 ? 180.324 173.964 100.750 1.00 98.72  ? 150 GLY H C   1 
ATOM   5349 O  O   . GLY B 2 150 ? 180.167 175.106 100.311 1.00 98.72  ? 150 GLY H O   1 
ATOM   5350 N  N   . TYR B 2 151 ? 179.898 173.595 101.955 1.00 94.07  ? 151 TYR H N   1 
ATOM   5351 C  CA  . TYR B 2 151 ? 179.306 174.537 102.890 1.00 94.07  ? 151 TYR H CA  1 
ATOM   5352 C  C   . TYR B 2 151 ? 179.953 174.356 104.255 1.00 94.07  ? 151 TYR H C   1 
ATOM   5353 O  O   . TYR B 2 151 ? 180.591 173.338 104.531 1.00 94.07  ? 151 TYR H O   1 
ATOM   5354 C  CB  . TYR B 2 151 ? 177.782 174.363 102.994 1.00 94.07  ? 151 TYR H CB  1 
ATOM   5355 C  CG  . TYR B 2 151 ? 177.322 173.067 103.632 1.00 94.07  ? 151 TYR H CG  1 
ATOM   5356 C  CD1 . TYR B 2 151 ? 177.158 171.916 102.874 1.00 94.07  ? 151 TYR H CD1 1 
ATOM   5357 C  CD2 . TYR B 2 151 ? 177.017 173.006 104.987 1.00 94.07  ? 151 TYR H CD2 1 
ATOM   5358 C  CE1 . TYR B 2 151 ? 176.730 170.738 103.453 1.00 94.07  ? 151 TYR H CE1 1 
ATOM   5359 C  CE2 . TYR B 2 151 ? 176.591 171.835 105.572 1.00 94.07  ? 151 TYR H CE2 1 
ATOM   5360 C  CZ  . TYR B 2 151 ? 176.446 170.707 104.802 1.00 94.07  ? 151 TYR H CZ  1 
ATOM   5361 O  OH  . TYR B 2 151 ? 176.018 169.543 105.389 1.00 94.07  ? 151 TYR H OH  1 
ATOM   5362 N  N   . PHE B 2 152 ? 179.774 175.365 105.112 1.00 88.53  ? 152 PHE H N   1 
ATOM   5363 C  CA  . PHE B 2 152 ? 180.297 175.327 106.469 1.00 88.53  ? 152 PHE H CA  1 
ATOM   5364 C  C   . PHE B 2 152 ? 179.576 176.381 107.287 1.00 88.53  ? 152 PHE H C   1 
ATOM   5365 O  O   . PHE B 2 152 ? 179.357 177.489 106.778 1.00 88.53  ? 152 PHE H O   1 
ATOM   5366 C  CB  . PHE B 2 152 ? 181.807 175.586 106.494 1.00 88.53  ? 152 PHE H CB  1 
ATOM   5367 C  CG  . PHE B 2 152 ? 182.467 175.181 107.774 1.00 88.53  ? 152 PHE H CG  1 
ATOM   5368 C  CD1 . PHE B 2 152 ? 182.726 173.849 108.040 1.00 88.53  ? 152 PHE H CD1 1 
ATOM   5369 C  CD2 . PHE B 2 152 ? 182.820 176.129 108.716 1.00 88.53  ? 152 PHE H CD2 1 
ATOM   5370 C  CE1 . PHE B 2 152 ? 183.330 173.468 109.221 1.00 88.53  ? 152 PHE H CE1 1 
ATOM   5371 C  CE2 . PHE B 2 152 ? 183.423 175.755 109.898 1.00 88.53  ? 152 PHE H CE2 1 
ATOM   5372 C  CZ  . PHE B 2 152 ? 183.678 174.422 110.150 1.00 88.53  ? 152 PHE H CZ  1 
ATOM   5373 N  N   . PRO B 2 153 ? 179.202 176.097 108.542 1.00 88.45  ? 153 PRO H N   1 
ATOM   5374 C  CA  . PRO B 2 153 ? 179.302 174.828 109.263 1.00 88.45  ? 153 PRO H CA  1 
ATOM   5375 C  C   . PRO B 2 153 ? 177.968 174.112 109.447 1.00 88.45  ? 153 PRO H C   1 
ATOM   5376 O  O   . PRO B 2 153 ? 176.941 174.496 108.893 1.00 88.45  ? 153 PRO H O   1 
ATOM   5377 C  CB  . PRO B 2 153 ? 179.877 175.272 110.607 1.00 88.45  ? 153 PRO H CB  1 
ATOM   5378 C  CG  . PRO B 2 153 ? 179.209 176.614 110.844 1.00 88.45  ? 153 PRO H CG  1 
ATOM   5379 C  CD  . PRO B 2 153 ? 178.881 177.190 109.473 1.00 88.45  ? 153 PRO H CD  1 
ATOM   5380 N  N   . GLU B 2 154 ? 178.008 173.038 110.228 1.00 95.89  ? 154 GLU H N   1 
ATOM   5381 C  CA  . GLU B 2 154 ? 176.801 172.350 110.658 1.00 95.89  ? 154 GLU H CA  1 
ATOM   5382 C  C   . GLU B 2 154 ? 175.951 173.293 111.510 1.00 95.89  ? 154 GLU H C   1 
ATOM   5383 O  O   . GLU B 2 154 ? 176.490 174.019 112.354 1.00 95.89  ? 154 GLU H O   1 
ATOM   5384 C  CB  . GLU B 2 154 ? 177.195 171.099 111.454 1.00 95.89  ? 154 GLU H CB  1 
ATOM   5385 C  CG  . GLU B 2 154 ? 176.066 170.227 111.979 1.00 95.89  ? 154 GLU H CG  1 
ATOM   5386 C  CD  . GLU B 2 154 ? 175.443 169.366 110.896 1.00 95.89  ? 154 GLU H CD  1 
ATOM   5387 O  OE1 . GLU B 2 154 ? 176.073 169.203 109.830 1.00 95.89  ? 154 GLU H OE1 1 
ATOM   5388 O  OE2 . GLU B 2 154 ? 174.325 168.852 111.110 1.00 95.89  ? 154 GLU H OE2 1 
ATOM   5389 N  N   . PRO B 2 155 ? 174.620 173.315 111.323 1.00 96.47  ? 155 PRO H N   1 
ATOM   5390 C  CA  . PRO B 2 155 ? 173.809 172.501 110.415 1.00 96.47  ? 155 PRO H CA  1 
ATOM   5391 C  C   . PRO B 2 155 ? 173.218 173.225 109.211 1.00 96.47  ? 155 PRO H C   1 
ATOM   5392 O  O   . PRO B 2 155 ? 173.322 174.437 109.052 1.00 96.47  ? 155 PRO H O   1 
ATOM   5393 C  CB  . PRO B 2 155 ? 172.696 172.012 111.345 1.00 96.47  ? 155 PRO H CB  1 
ATOM   5394 C  CG  . PRO B 2 155 ? 172.474 173.191 112.294 1.00 96.47  ? 155 PRO H CG  1 
ATOM   5395 C  CD  . PRO B 2 155 ? 173.758 174.012 112.292 1.00 96.47  ? 155 PRO H CD  1 
ATOM   5396 N  N   . VAL B 2 156 ? 172.586 172.438 108.343 1.00 103.52 ? 156 VAL H N   1 
ATOM   5397 C  CA  . VAL B 2 156 ? 171.810 172.929 107.212 1.00 103.52 ? 156 VAL H CA  1 
ATOM   5398 C  C   . VAL B 2 156 ? 170.495 172.164 107.201 1.00 103.52 ? 156 VAL H C   1 
ATOM   5399 O  O   . VAL B 2 156 ? 170.495 170.928 107.223 1.00 103.52 ? 156 VAL H O   1 
ATOM   5400 C  CB  . VAL B 2 156 ? 172.556 172.752 105.878 1.00 103.52 ? 156 VAL H CB  1 
ATOM   5401 C  CG1 . VAL B 2 156 ? 171.590 172.778 104.703 1.00 103.52 ? 156 VAL H CG1 1 
ATOM   5402 C  CG2 . VAL B 2 156 ? 173.597 173.835 105.716 1.00 103.52 ? 156 VAL H CG2 1 
ATOM   5403 N  N   . THR B 2 157 ? 169.381 172.890 107.183 1.00 110.08 ? 157 THR H N   1 
ATOM   5404 C  CA  . THR B 2 157 ? 168.063 172.277 107.098 1.00 110.08 ? 157 THR H CA  1 
ATOM   5405 C  C   . THR B 2 157 ? 167.688 172.123 105.629 1.00 110.08 ? 157 THR H C   1 
ATOM   5406 O  O   . THR B 2 157 ? 167.612 173.114 104.896 1.00 110.08 ? 157 THR H O   1 
ATOM   5407 C  CB  . THR B 2 157 ? 167.023 173.118 107.835 1.00 110.08 ? 157 THR H CB  1 
ATOM   5408 O  OG1 . THR B 2 157 ? 167.346 173.163 109.231 1.00 110.08 ? 157 THR H OG1 1 
ATOM   5409 C  CG2 . THR B 2 157 ? 165.637 172.518 107.661 1.00 110.08 ? 157 THR H CG2 1 
ATOM   5410 N  N   . LEU B 2 158 ? 167.459 170.884 105.199 1.00 112.64 ? 158 LEU H N   1 
ATOM   5411 C  CA  . LEU B 2 158 ? 167.140 170.597 103.808 1.00 112.64 ? 158 LEU H CA  1 
ATOM   5412 C  C   . LEU B 2 158 ? 165.844 169.807 103.748 1.00 112.64 ? 158 LEU H C   1 
ATOM   5413 O  O   . LEU B 2 158 ? 165.678 168.819 104.471 1.00 112.64 ? 158 LEU H O   1 
ATOM   5414 C  CB  . LEU B 2 158 ? 168.275 169.821 103.123 1.00 112.64 ? 158 LEU H CB  1 
ATOM   5415 C  CG  . LEU B 2 158 ? 168.258 169.712 101.592 1.00 112.64 ? 158 LEU H CG  1 
ATOM   5416 C  CD1 . LEU B 2 158 ? 169.674 169.768 101.048 1.00 112.64 ? 158 LEU H CD1 1 
ATOM   5417 C  CD2 . LEU B 2 158 ? 167.570 168.446 101.106 1.00 112.64 ? 158 LEU H CD2 1 
ATOM   5418 N  N   . THR B 2 159 ? 164.930 170.250 102.887 1.00 123.31 ? 159 THR H N   1 
ATOM   5419 C  CA  . THR B 2 159 ? 163.695 169.529 102.607 1.00 123.31 ? 159 THR H CA  1 
ATOM   5420 C  C   . THR B 2 159 ? 163.540 169.370 101.101 1.00 123.31 ? 159 THR H C   1 
ATOM   5421 O  O   . THR B 2 159 ? 164.482 169.630 100.346 1.00 123.31 ? 159 THR H O   1 
ATOM   5422 C  CB  . THR B 2 159 ? 162.481 170.255 103.193 1.00 123.31 ? 159 THR H CB  1 
ATOM   5423 O  OG1 . THR B 2 159 ? 162.455 171.607 102.717 1.00 123.31 ? 159 THR H OG1 1 
ATOM   5424 C  CG2 . THR B 2 159 ? 162.522 170.251 104.716 1.00 123.31 ? 159 THR H CG2 1 
ATOM   5425 N  N   . TRP B 2 160 ? 162.365 168.937 100.653 1.00 127.42 ? 160 TRP H N   1 
ATOM   5426 C  CA  . TRP B 2 160 ? 162.060 168.859 99.231  1.00 127.42 ? 160 TRP H CA  1 
ATOM   5427 C  C   . TRP B 2 160 ? 160.759 169.599 98.960  1.00 127.42 ? 160 TRP H C   1 
ATOM   5428 O  O   . TRP B 2 160 ? 159.782 169.426 99.697  1.00 127.42 ? 160 TRP H O   1 
ATOM   5429 C  CB  . TRP B 2 160 ? 161.962 167.406 98.763  1.00 127.42 ? 160 TRP H CB  1 
ATOM   5430 C  CG  . TRP B 2 160 ? 163.296 166.763 98.559  1.00 127.42 ? 160 TRP H CG  1 
ATOM   5431 C  CD1 . TRP B 2 160 ? 164.183 166.394 99.526  1.00 127.42 ? 160 TRP H CD1 1 
ATOM   5432 C  CD2 . TRP B 2 160 ? 163.896 166.410 97.308  1.00 127.42 ? 160 TRP H CD2 1 
ATOM   5433 N  NE1 . TRP B 2 160 ? 165.297 165.832 98.956  1.00 127.42 ? 160 TRP H NE1 1 
ATOM   5434 C  CE2 . TRP B 2 160 ? 165.146 165.829 97.594  1.00 127.42 ? 160 TRP H CE2 1 
ATOM   5435 C  CE3 . TRP B 2 160 ? 163.496 166.525 95.974  1.00 127.42 ? 160 TRP H CE3 1 
ATOM   5436 C  CZ2 . TRP B 2 160 ? 166.000 165.366 96.596  1.00 127.42 ? 160 TRP H CZ2 1 
ATOM   5437 C  CZ3 . TRP B 2 160 ? 164.345 166.066 94.985  1.00 127.42 ? 160 TRP H CZ3 1 
ATOM   5438 C  CH2 . TRP B 2 160 ? 165.583 165.494 95.301  1.00 127.42 ? 160 TRP H CH2 1 
ATOM   5439 N  N   . ASN B 2 161 ? 160.761 170.412 97.896  1.00 130.49 ? 161 ASN H N   1 
ATOM   5440 C  CA  . ASN B 2 161 ? 159.629 171.256 97.496  1.00 130.49 ? 161 ASN H CA  1 
ATOM   5441 C  C   . ASN B 2 161 ? 159.180 172.171 98.637  1.00 130.49 ? 161 ASN H C   1 
ATOM   5442 O  O   . ASN B 2 161 ? 157.985 172.323 98.906  1.00 130.49 ? 161 ASN H O   1 
ATOM   5443 C  CB  . ASN B 2 161 ? 158.462 170.413 96.972  1.00 130.49 ? 161 ASN H CB  1 
ATOM   5444 C  CG  . ASN B 2 161 ? 158.901 169.373 95.963  1.00 130.49 ? 161 ASN H CG  1 
ATOM   5445 O  OD1 . ASN B 2 161 ? 159.498 169.700 94.938  1.00 130.49 ? 161 ASN H OD1 1 
ATOM   5446 N  ND2 . ASN B 2 161 ? 158.601 168.111 96.245  1.00 130.49 ? 161 ASN H ND2 1 
ATOM   5447 N  N   . SER B 2 162 ? 160.168 172.782 99.304  1.00 130.81 ? 162 SER H N   1 
ATOM   5448 C  CA  . SER B 2 162 ? 159.963 173.725 100.411 1.00 130.81 ? 162 SER H CA  1 
ATOM   5449 C  C   . SER B 2 162 ? 159.155 173.105 101.551 1.00 130.81 ? 162 SER H C   1 
ATOM   5450 O  O   . SER B 2 162 ? 158.260 173.735 102.118 1.00 130.81 ? 162 SER H O   1 
ATOM   5451 C  CB  . SER B 2 162 ? 159.314 175.025 99.926  1.00 130.81 ? 162 SER H CB  1 
ATOM   5452 O  OG  . SER B 2 162 ? 160.103 175.645 98.926  1.00 130.81 ? 162 SER H OG  1 
ATOM   5453 N  N   . GLY B 2 163 ? 159.472 171.857 101.888 1.00 130.54 ? 163 GLY H N   1 
ATOM   5454 C  CA  . GLY B 2 163 ? 158.828 171.179 102.991 1.00 130.54 ? 163 GLY H CA  1 
ATOM   5455 C  C   . GLY B 2 163 ? 157.493 170.545 102.674 1.00 130.54 ? 163 GLY H C   1 
ATOM   5456 O  O   . GLY B 2 163 ? 156.891 169.936 103.568 1.00 130.54 ? 163 GLY H O   1 
ATOM   5457 N  N   . SER B 2 164 ? 157.005 170.665 101.438 1.00 133.32 ? 164 SER H N   1 
ATOM   5458 C  CA  . SER B 2 164 ? 155.733 170.050 101.082 1.00 133.32 ? 164 SER H CA  1 
ATOM   5459 C  C   . SER B 2 164 ? 155.840 168.538 100.948 1.00 133.32 ? 164 SER H C   1 
ATOM   5460 O  O   . SER B 2 164 ? 154.832 167.842 101.107 1.00 133.32 ? 164 SER H O   1 
ATOM   5461 C  CB  . SER B 2 164 ? 155.201 170.648 99.779  1.00 133.32 ? 164 SER H CB  1 
ATOM   5462 O  OG  . SER B 2 164 ? 155.704 169.948 98.656  1.00 133.32 ? 164 SER H OG  1 
ATOM   5463 N  N   . LEU B 2 165 ? 157.029 168.018 100.661 1.00 132.49 ? 165 LEU H N   1 
ATOM   5464 C  CA  . LEU B 2 165 ? 157.250 166.587 100.504 1.00 132.49 ? 165 LEU H CA  1 
ATOM   5465 C  C   . LEU B 2 165 ? 158.082 166.095 101.681 1.00 132.49 ? 165 LEU H C   1 
ATOM   5466 O  O   . LEU B 2 165 ? 159.200 166.574 101.898 1.00 132.49 ? 165 LEU H O   1 
ATOM   5467 C  CB  . LEU B 2 165 ? 157.944 166.287 99.173  1.00 132.49 ? 165 LEU H CB  1 
ATOM   5468 C  CG  . LEU B 2 165 ? 157.980 164.846 98.654  1.00 132.49 ? 165 LEU H CG  1 
ATOM   5469 C  CD1 . LEU B 2 165 ? 157.899 164.842 97.136  1.00 132.49 ? 165 LEU H CD1 1 
ATOM   5470 C  CD2 . LEU B 2 165 ? 159.229 164.106 99.108  1.00 132.49 ? 165 LEU H CD2 1 
ATOM   5471 N  N   . SER B 2 166 ? 157.534 165.141 102.434 1.00 129.78 ? 166 SER H N   1 
ATOM   5472 C  CA  . SER B 2 166 ? 158.239 164.571 103.572 1.00 129.78 ? 166 SER H CA  1 
ATOM   5473 C  C   . SER B 2 166 ? 158.091 163.060 103.677 1.00 129.78 ? 166 SER H C   1 
ATOM   5474 O  O   . SER B 2 166 ? 158.567 162.481 104.658 1.00 129.78 ? 166 SER H O   1 
ATOM   5475 C  CB  . SER B 2 166 ? 157.759 165.220 104.880 1.00 129.78 ? 166 SER H CB  1 
ATOM   5476 O  OG  . SER B 2 166 ? 157.933 166.625 104.844 1.00 129.78 ? 166 SER H OG  1 
ATOM   5477 N  N   . SER B 2 167 ? 157.452 162.408 102.711 1.00 128.89 ? 167 SER H N   1 
ATOM   5478 C  CA  . SER B 2 167 ? 157.292 160.961 102.700 1.00 128.89 ? 167 SER H CA  1 
ATOM   5479 C  C   . SER B 2 167 ? 158.185 160.372 101.619 1.00 128.89 ? 167 SER H C   1 
ATOM   5480 O  O   . SER B 2 167 ? 158.176 160.844 100.476 1.00 128.89 ? 167 SER H O   1 
ATOM   5481 C  CB  . SER B 2 167 ? 155.832 160.572 102.458 1.00 128.89 ? 167 SER H CB  1 
ATOM   5482 O  OG  . SER B 2 167 ? 155.627 159.189 102.687 1.00 128.89 ? 167 SER H OG  1 
ATOM   5483 N  N   . GLY B 2 168 ? 158.951 159.346 101.979 1.00 127.16 ? 168 GLY H N   1 
ATOM   5484 C  CA  . GLY B 2 168 ? 159.909 158.771 101.061 1.00 127.16 ? 168 GLY H CA  1 
ATOM   5485 C  C   . GLY B 2 168 ? 161.198 159.545 100.923 1.00 127.16 ? 168 GLY H C   1 
ATOM   5486 O  O   . GLY B 2 168 ? 161.960 159.286 99.985  1.00 127.16 ? 168 GLY H O   1 
ATOM   5487 N  N   . VAL B 2 169 ? 161.463 160.490 101.820 1.00 121.26 ? 169 VAL H N   1 
ATOM   5488 C  CA  . VAL B 2 169 ? 162.677 161.296 101.792 1.00 121.26 ? 169 VAL H CA  1 
ATOM   5489 C  C   . VAL B 2 169 ? 163.686 160.684 102.759 1.00 121.26 ? 169 VAL H C   1 
ATOM   5490 O  O   . VAL B 2 169 ? 163.313 160.179 103.826 1.00 121.26 ? 169 VAL H O   1 
ATOM   5491 C  CB  . VAL B 2 169 ? 162.370 162.771 102.127 1.00 121.26 ? 169 VAL H CB  1 
ATOM   5492 C  CG1 . VAL B 2 169 ? 161.756 162.923 103.518 1.00 121.26 ? 169 VAL H CG1 1 
ATOM   5493 C  CG2 . VAL B 2 169 ? 163.612 163.649 101.980 1.00 121.26 ? 169 VAL H CG2 1 
ATOM   5494 N  N   . HIS B 2 170 ? 164.956 160.672 102.359 1.00 110.62 ? 170 HIS H N   1 
ATOM   5495 C  CA  . HIS B 2 170 ? 166.043 160.188 103.200 1.00 110.62 ? 170 HIS H CA  1 
ATOM   5496 C  C   . HIS B 2 170 ? 167.201 161.168 103.118 1.00 110.62 ? 170 HIS H C   1 
ATOM   5497 O  O   . HIS B 2 170 ? 167.788 161.351 102.046 1.00 110.62 ? 170 HIS H O   1 
ATOM   5498 C  CB  . HIS B 2 170 ? 166.490 158.786 102.781 1.00 110.62 ? 170 HIS H CB  1 
ATOM   5499 C  CG  . HIS B 2 170 ? 165.761 157.689 103.491 1.00 110.62 ? 170 HIS H CG  1 
ATOM   5500 N  ND1 . HIS B 2 170 ? 165.622 156.423 102.966 1.00 110.62 ? 170 HIS H ND1 1 
ATOM   5501 C  CD2 . HIS B 2 170 ? 165.135 157.670 104.691 1.00 110.62 ? 170 HIS H CD2 1 
ATOM   5502 C  CE1 . HIS B 2 170 ? 164.937 155.672 103.810 1.00 110.62 ? 170 HIS H CE1 1 
ATOM   5503 N  NE2 . HIS B 2 170 ? 164.630 156.405 104.865 1.00 110.62 ? 170 HIS H NE2 1 
ATOM   5504 N  N   . THR B 2 171 ? 167.521 161.797 104.241 1.00 103.02 ? 171 THR H N   1 
ATOM   5505 C  CA  . THR B 2 171 ? 168.637 162.722 104.333 1.00 103.02 ? 171 THR H CA  1 
ATOM   5506 C  C   . THR B 2 171 ? 169.882 161.997 104.832 1.00 103.02 ? 171 THR H C   1 
ATOM   5507 O  O   . THR B 2 171 ? 169.823 160.872 105.332 1.00 103.02 ? 171 THR H O   1 
ATOM   5508 C  CB  . THR B 2 171 ? 168.295 163.893 105.257 1.00 103.02 ? 171 THR H CB  1 
ATOM   5509 O  OG1 . THR B 2 171 ? 169.371 164.839 105.252 1.00 103.02 ? 171 THR H OG1 1 
ATOM   5510 C  CG2 . THR B 2 171 ? 168.070 163.398 106.675 1.00 103.02 ? 171 THR H CG2 1 
ATOM   5511 N  N   . PHE B 2 172 ? 171.025 162.661 104.688 1.00 95.12  ? 172 PHE H N   1 
ATOM   5512 C  CA  . PHE B 2 172 ? 172.278 162.076 105.116 1.00 95.12  ? 172 PHE H CA  1 
ATOM   5513 C  C   . PHE B 2 172 ? 173.046 163.057 105.990 1.00 95.12  ? 172 PHE H C   1 
ATOM   5514 O  O   . PHE B 2 172 ? 173.029 164.263 105.725 1.00 95.12  ? 172 PHE H O   1 
ATOM   5515 C  CB  . PHE B 2 172 ? 173.135 161.684 103.909 1.00 95.12  ? 172 PHE H CB  1 
ATOM   5516 C  CG  . PHE B 2 172 ? 172.490 160.665 103.022 1.00 95.12  ? 172 PHE H CG  1 
ATOM   5517 C  CD1 . PHE B 2 172 ? 172.466 159.331 103.382 1.00 95.12  ? 172 PHE H CD1 1 
ATOM   5518 C  CD2 . PHE B 2 172 ? 171.900 161.041 101.831 1.00 95.12  ? 172 PHE H CD2 1 
ATOM   5519 C  CE1 . PHE B 2 172 ? 171.868 158.391 102.567 1.00 95.12  ? 172 PHE H CE1 1 
ATOM   5520 C  CE2 . PHE B 2 172 ? 171.300 160.106 101.014 1.00 95.12  ? 172 PHE H CE2 1 
ATOM   5521 C  CZ  . PHE B 2 172 ? 171.282 158.781 101.381 1.00 95.12  ? 172 PHE H CZ  1 
ATOM   5522 N  N   . PRO B 2 173 ? 173.708 162.580 107.041 1.00 91.88  ? 173 PRO H N   1 
ATOM   5523 C  CA  . PRO B 2 173 ? 174.516 163.476 107.871 1.00 91.88  ? 173 PRO H CA  1 
ATOM   5524 C  C   . PRO B 2 173 ? 175.717 164.011 107.111 1.00 91.88  ? 173 PRO H C   1 
ATOM   5525 O  O   . PRO B 2 173 ? 176.226 163.382 106.181 1.00 91.88  ? 173 PRO H O   1 
ATOM   5526 C  CB  . PRO B 2 173 ? 174.953 162.584 109.040 1.00 91.88  ? 173 PRO H CB  1 
ATOM   5527 C  CG  . PRO B 2 173 ? 173.981 161.451 109.042 1.00 91.88  ? 173 PRO H CG  1 
ATOM   5528 C  CD  . PRO B 2 173 ? 173.632 161.225 107.607 1.00 91.88  ? 173 PRO H CD  1 
ATOM   5529 N  N   . ALA B 2 174 ? 176.154 165.201 107.511 1.00 91.90  ? 174 ALA H N   1 
ATOM   5530 C  CA  . ALA B 2 174 ? 177.308 165.827 106.885 1.00 91.90  ? 174 ALA H CA  1 
ATOM   5531 C  C   . ALA B 2 174 ? 178.586 165.067 107.222 1.00 91.90  ? 174 ALA H C   1 
ATOM   5532 O  O   . ALA B 2 174 ? 178.711 164.450 108.283 1.00 91.90  ? 174 ALA H O   1 
ATOM   5533 C  CB  . ALA B 2 174 ? 177.436 167.280 107.335 1.00 91.90  ? 174 ALA H CB  1 
ATOM   5534 N  N   . VAL B 2 175 ? 179.542 165.120 106.301 1.00 92.00  ? 175 VAL H N   1 
ATOM   5535 C  CA  . VAL B 2 175 ? 180.821 164.441 106.451 1.00 92.00  ? 175 VAL H CA  1 
ATOM   5536 C  C   . VAL B 2 175 ? 181.934 165.479 106.359 1.00 92.00  ? 175 VAL H C   1 
ATOM   5537 O  O   . VAL B 2 175 ? 181.879 166.398 105.534 1.00 92.00  ? 175 VAL H O   1 
ATOM   5538 C  CB  . VAL B 2 175 ? 180.982 163.310 105.405 1.00 92.00  ? 175 VAL H CB  1 
ATOM   5539 C  CG1 . VAL B 2 175 ? 180.845 163.839 103.985 1.00 92.00  ? 175 VAL H CG1 1 
ATOM   5540 C  CG2 . VAL B 2 175 ? 182.299 162.567 105.591 1.00 92.00  ? 175 VAL H CG2 1 
ATOM   5541 N  N   . LEU B 2 176 ? 182.916 165.366 107.249 1.00 96.97  ? 176 LEU H N   1 
ATOM   5542 C  CA  . LEU B 2 176 ? 183.996 166.338 107.355 1.00 96.97  ? 176 LEU H CA  1 
ATOM   5543 C  C   . LEU B 2 176 ? 185.235 165.794 106.656 1.00 96.97  ? 176 LEU H C   1 
ATOM   5544 O  O   . LEU B 2 176 ? 185.787 164.770 107.072 1.00 96.97  ? 176 LEU H O   1 
ATOM   5545 C  CB  . LEU B 2 176 ? 184.300 166.651 108.822 1.00 96.97  ? 176 LEU H CB  1 
ATOM   5546 C  CG  . LEU B 2 176 ? 185.191 167.850 109.170 1.00 96.97  ? 176 LEU H CG  1 
ATOM   5547 C  CD1 . LEU B 2 176 ? 184.693 168.522 110.437 1.00 96.97  ? 176 LEU H CD1 1 
ATOM   5548 C  CD2 . LEU B 2 176 ? 186.652 167.446 109.342 1.00 96.97  ? 176 LEU H CD2 1 
ATOM   5549 N  N   . GLN B 2 177 ? 185.667 166.480 105.601 1.00 100.28 ? 177 GLN H N   1 
ATOM   5550 C  CA  . GLN B 2 177 ? 186.970 166.232 105.004 1.00 100.28 ? 177 GLN H CA  1 
ATOM   5551 C  C   . GLN B 2 177 ? 187.435 167.506 104.314 1.00 100.28 ? 177 GLN H C   1 
ATOM   5552 O  O   . GLN B 2 177 ? 186.632 168.210 103.693 1.00 100.28 ? 177 GLN H O   1 
ATOM   5553 C  CB  . GLN B 2 177 ? 186.948 165.045 104.027 1.00 100.28 ? 177 GLN H CB  1 
ATOM   5554 C  CG  . GLN B 2 177 ? 186.044 165.192 102.815 1.00 100.28 ? 177 GLN H CG  1 
ATOM   5555 C  CD  . GLN B 2 177 ? 185.500 163.858 102.344 1.00 100.28 ? 177 GLN H CD  1 
ATOM   5556 O  OE1 . GLN B 2 177 ? 185.059 163.037 103.148 1.00 100.28 ? 177 GLN H OE1 1 
ATOM   5557 N  NE2 . GLN B 2 177 ? 185.538 163.631 101.035 1.00 100.28 ? 177 GLN H NE2 1 
ATOM   5558 N  N   . SER B 2 178 ? 188.732 167.802 104.465 1.00 103.07 ? 178 SER H N   1 
ATOM   5559 C  CA  . SER B 2 178 ? 189.376 169.008 103.932 1.00 103.07 ? 178 SER H CA  1 
ATOM   5560 C  C   . SER B 2 178 ? 188.703 170.289 104.422 1.00 103.07 ? 178 SER H C   1 
ATOM   5561 O  O   . SER B 2 178 ? 188.661 171.287 103.699 1.00 103.07 ? 178 SER H O   1 
ATOM   5562 C  CB  . SER B 2 178 ? 189.435 168.983 102.400 1.00 103.07 ? 178 SER H CB  1 
ATOM   5563 O  OG  . SER B 2 178 ? 188.172 169.287 101.834 1.00 103.07 ? 178 SER H OG  1 
ATOM   5564 N  N   . ASP B 2 179 ? 188.182 170.253 105.656 1.00 97.67  ? 179 ASP H N   1 
ATOM   5565 C  CA  . ASP B 2 179 ? 187.490 171.374 106.306 1.00 97.67  ? 179 ASP H CA  1 
ATOM   5566 C  C   . ASP B 2 179 ? 186.279 171.857 105.508 1.00 97.67  ? 179 ASP H C   1 
ATOM   5567 O  O   . ASP B 2 179 ? 185.946 173.044 105.526 1.00 97.67  ? 179 ASP H O   1 
ATOM   5568 C  CB  . ASP B 2 179 ? 188.445 172.540 106.589 1.00 97.67  ? 179 ASP H CB  1 
ATOM   5569 N  N   . LEU B 2 180 ? 185.607 170.945 104.807 1.00 96.34  ? 180 LEU H N   1 
ATOM   5570 C  CA  . LEU B 2 180 ? 184.374 171.244 104.093 1.00 96.34  ? 180 LEU H CA  1 
ATOM   5571 C  C   . LEU B 2 180 ? 183.341 170.164 104.382 1.00 96.34  ? 180 LEU H C   1 
ATOM   5572 O  O   . LEU B 2 180 ? 183.680 169.050 104.790 1.00 96.34  ? 180 LEU H O   1 
ATOM   5573 C  CB  . LEU B 2 180 ? 184.587 171.355 102.572 1.00 96.34  ? 180 LEU H CB  1 
ATOM   5574 C  CG  . LEU B 2 180 ? 184.964 172.706 101.951 1.00 96.34  ? 180 LEU H CG  1 
ATOM   5575 C  CD1 . LEU B 2 180 ? 186.400 173.102 102.231 1.00 96.34  ? 180 LEU H CD1 1 
ATOM   5576 C  CD2 . LEU B 2 180 ? 184.705 172.684 100.452 1.00 96.34  ? 180 LEU H CD2 1 
ATOM   5577 N  N   . TYR B 2 181 ? 182.075 170.507 104.166 1.00 92.51  ? 181 TYR H N   1 
ATOM   5578 C  CA  . TYR B 2 181 ? 180.962 169.601 104.398 1.00 92.51  ? 181 TYR H CA  1 
ATOM   5579 C  C   . TYR B 2 181 ? 180.273 169.248 103.087 1.00 92.51  ? 181 TYR H C   1 
ATOM   5580 O  O   . TYR B 2 181 ? 180.312 170.001 102.111 1.00 92.51  ? 181 TYR H O   1 
ATOM   5581 C  CB  . TYR B 2 181 ? 179.943 170.214 105.364 1.00 92.51  ? 181 TYR H CB  1 
ATOM   5582 C  CG  . TYR B 2 181 ? 180.300 170.058 106.821 1.00 92.51  ? 181 TYR H CG  1 
ATOM   5583 C  CD1 . TYR B 2 181 ? 181.368 169.266 107.214 1.00 92.51  ? 181 TYR H CD1 1 
ATOM   5584 C  CD2 . TYR B 2 181 ? 179.561 170.698 107.805 1.00 92.51  ? 181 TYR H CD2 1 
ATOM   5585 C  CE1 . TYR B 2 181 ? 181.692 169.120 108.544 1.00 92.51  ? 181 TYR H CE1 1 
ATOM   5586 C  CE2 . TYR B 2 181 ? 179.878 170.556 109.138 1.00 92.51  ? 181 TYR H CE2 1 
ATOM   5587 C  CZ  . TYR B 2 181 ? 180.945 169.767 109.502 1.00 92.51  ? 181 TYR H CZ  1 
ATOM   5588 O  OH  . TYR B 2 181 ? 181.264 169.624 110.832 1.00 92.51  ? 181 TYR H OH  1 
ATOM   5589 N  N   . THR B 2 182 ? 179.638 168.078 103.080 1.00 97.15  ? 182 THR H N   1 
ATOM   5590 C  CA  . THR B 2 182 ? 178.857 167.615 101.942 1.00 97.15  ? 182 THR H CA  1 
ATOM   5591 C  C   . THR B 2 182 ? 177.587 166.960 102.459 1.00 97.15  ? 182 THR H C   1 
ATOM   5592 O  O   . THR B 2 182 ? 177.645 166.118 103.360 1.00 97.15  ? 182 THR H O   1 
ATOM   5593 C  CB  . THR B 2 182 ? 179.649 166.623 101.082 1.00 97.15  ? 182 THR H CB  1 
ATOM   5594 O  OG1 . THR B 2 182 ? 180.982 167.110 100.890 1.00 97.15  ? 182 THR H OG1 1 
ATOM   5595 C  CG2 . THR B 2 182 ? 178.983 166.444 99.728  1.00 97.15  ? 182 THR H CG2 1 
ATOM   5596 N  N   . LEU B 2 183 ? 176.447 167.347 101.893 1.00 98.17  ? 183 LEU H N   1 
ATOM   5597 C  CA  . LEU B 2 183 ? 175.158 166.799 102.284 1.00 98.17  ? 183 LEU H CA  1 
ATOM   5598 C  C   . LEU B 2 183 ? 174.376 166.422 101.037 1.00 98.17  ? 183 LEU H C   1 
ATOM   5599 O  O   . LEU B 2 183 ? 174.484 167.074 99.996  1.00 98.17  ? 183 LEU H O   1 
ATOM   5600 C  CB  . LEU B 2 183 ? 174.358 167.799 103.136 1.00 98.17  ? 183 LEU H CB  1 
ATOM   5601 C  CG  . LEU B 2 183 ? 173.139 167.296 103.916 1.00 98.17  ? 183 LEU H CG  1 
ATOM   5602 C  CD1 . LEU B 2 183 ? 173.064 167.987 105.264 1.00 98.17  ? 183 LEU H CD1 1 
ATOM   5603 C  CD2 . LEU B 2 183 ? 171.848 167.523 103.148 1.00 98.17  ? 183 LEU H CD2 1 
ATOM   5604 N  N   . SER B 2 184 ? 173.583 165.360 101.154 1.00 98.81  ? 184 SER H N   1 
ATOM   5605 C  CA  . SER B 2 184 ? 172.762 164.878 100.056 1.00 98.81  ? 184 SER H CA  1 
ATOM   5606 C  C   . SER B 2 184 ? 171.420 164.420 100.603 1.00 98.81  ? 184 SER H C   1 
ATOM   5607 O  O   . SER B 2 184 ? 171.268 164.173 101.801 1.00 98.81  ? 184 SER H O   1 
ATOM   5608 C  CB  . SER B 2 184 ? 173.442 163.730 99.302  1.00 98.81  ? 184 SER H CB  1 
ATOM   5609 O  OG  . SER B 2 184 ? 174.773 164.067 98.953  1.00 98.81  ? 184 SER H OG  1 
ATOM   5610 N  N   . SER B 2 185 ? 170.440 164.326 99.709  1.00 108.84 ? 185 SER H N   1 
ATOM   5611 C  CA  . SER B 2 185 ? 169.134 163.786 100.059 1.00 108.84 ? 185 SER H CA  1 
ATOM   5612 C  C   . SER B 2 185 ? 168.478 163.244 98.800  1.00 108.84 ? 185 SER H C   1 
ATOM   5613 O  O   . SER B 2 185 ? 168.628 163.811 97.715  1.00 108.84 ? 185 SER H O   1 
ATOM   5614 C  CB  . SER B 2 185 ? 168.238 164.839 100.714 1.00 108.84 ? 185 SER H CB  1 
ATOM   5615 O  OG  . SER B 2 185 ? 168.667 165.119 102.033 1.00 108.84 ? 185 SER H OG  1 
ATOM   5616 N  N   . SER B 2 186 ? 167.751 162.143 98.958  1.00 119.18 ? 186 SER H N   1 
ATOM   5617 C  CA  . SER B 2 186 ? 167.070 161.503 97.845  1.00 119.18 ? 186 SER H CA  1 
ATOM   5618 C  C   . SER B 2 186 ? 165.630 161.212 98.233  1.00 119.18 ? 186 SER H C   1 
ATOM   5619 O  O   . SER B 2 186 ? 165.319 160.979 99.403  1.00 119.18 ? 186 SER H O   1 
ATOM   5620 C  CB  . SER B 2 186 ? 167.763 160.204 97.423  1.00 119.18 ? 186 SER H CB  1 
ATOM   5621 O  OG  . SER B 2 186 ? 167.520 159.171 98.362  1.00 119.18 ? 186 SER H OG  1 
ATOM   5622 N  N   . VAL B 2 187 ? 164.752 161.229 97.231  1.00 127.68 ? 187 VAL H N   1 
ATOM   5623 C  CA  . VAL B 2 187 ? 163.336 160.957 97.424  1.00 127.68 ? 187 VAL H CA  1 
ATOM   5624 C  C   . VAL B 2 187 ? 162.902 159.889 96.431  1.00 127.68 ? 187 VAL H C   1 
ATOM   5625 O  O   . VAL B 2 187 ? 163.538 159.667 95.399  1.00 127.68 ? 187 VAL H O   1 
ATOM   5626 C  CB  . VAL B 2 187 ? 162.466 162.221 97.265  1.00 127.68 ? 187 VAL H CB  1 
ATOM   5627 C  CG1 . VAL B 2 187 ? 162.763 163.211 98.374  1.00 127.68 ? 187 VAL H CG1 1 
ATOM   5628 C  CG2 . VAL B 2 187 ? 162.703 162.857 95.905  1.00 127.68 ? 187 VAL H CG2 1 
ATOM   5629 N  N   . THR B 2 188 ? 161.800 159.224 96.761  1.00 135.55 ? 188 THR H N   1 
ATOM   5630 C  CA  . THR B 2 188 ? 161.225 158.181 95.926  1.00 135.55 ? 188 THR H CA  1 
ATOM   5631 C  C   . THR B 2 188 ? 159.923 158.685 95.322  1.00 135.55 ? 188 THR H C   1 
ATOM   5632 O  O   . THR B 2 188 ? 159.059 159.198 96.041  1.00 135.55 ? 188 THR H O   1 
ATOM   5633 C  CB  . THR B 2 188 ? 160.974 156.906 96.734  1.00 135.55 ? 188 THR H CB  1 
ATOM   5634 O  OG1 . THR B 2 188 ? 159.959 157.155 97.716  1.00 135.55 ? 188 THR H OG1 1 
ATOM   5635 C  CG2 . THR B 2 188 ? 162.248 156.461 97.434  1.00 135.55 ? 188 THR H CG2 1 
ATOM   5636 N  N   . VAL B 2 189 ? 159.788 158.542 94.004  1.00 142.55 ? 189 VAL H N   1 
ATOM   5637 C  CA  . VAL B 2 189 ? 158.587 158.953 93.292  1.00 142.55 ? 189 VAL H CA  1 
ATOM   5638 C  C   . VAL B 2 189 ? 158.166 157.831 92.353  1.00 142.55 ? 189 VAL H C   1 
ATOM   5639 O  O   . VAL B 2 189 ? 158.969 156.985 91.954  1.00 142.55 ? 189 VAL H O   1 
ATOM   5640 C  CB  . VAL B 2 189 ? 158.790 160.266 92.507  1.00 142.55 ? 189 VAL H CB  1 
ATOM   5641 N  N   . THR B 2 190 ? 156.883 157.833 92.005  1.00 148.66 ? 190 THR H N   1 
ATOM   5642 C  CA  . THR B 2 190 ? 156.347 156.840 91.091  1.00 148.66 ? 190 THR H CA  1 
ATOM   5643 C  C   . THR B 2 190 ? 156.593 157.260 89.643  1.00 148.66 ? 190 THR H C   1 
ATOM   5644 O  O   . THR B 2 190 ? 157.144 158.328 89.359  1.00 148.66 ? 190 THR H O   1 
ATOM   5645 C  CB  . THR B 2 190 ? 154.853 156.630 91.337  1.00 148.66 ? 190 THR H CB  1 
ATOM   5646 O  OG1 . THR B 2 190 ? 154.111 157.692 90.725  1.00 148.66 ? 190 THR H OG1 1 
ATOM   5647 C  CG2 . THR B 2 190 ? 154.558 156.605 92.830  1.00 148.66 ? 190 THR H CG2 1 
ATOM   5648 N  N   . SER B 2 191 ? 156.182 156.390 88.717  1.00 152.27 ? 191 SER H N   1 
ATOM   5649 C  CA  . SER B 2 191 ? 156.353 156.680 87.297  1.00 152.27 ? 191 SER H CA  1 
ATOM   5650 C  C   . SER B 2 191 ? 155.448 157.815 86.836  1.00 152.27 ? 191 SER H C   1 
ATOM   5651 O  O   . SER B 2 191 ? 155.843 158.610 85.976  1.00 152.27 ? 191 SER H O   1 
ATOM   5652 C  CB  . SER B 2 191 ? 156.085 155.425 86.467  1.00 152.27 ? 191 SER H CB  1 
ATOM   5653 O  OG  . SER B 2 191 ? 157.050 154.423 86.727  1.00 152.27 ? 191 SER H OG  1 
ATOM   5654 N  N   . SER B 2 192 ? 154.235 157.903 87.384  1.00 151.86 ? 192 SER H N   1 
ATOM   5655 C  CA  . SER B 2 192 ? 153.302 158.942 86.965  1.00 151.86 ? 192 SER H CA  1 
ATOM   5656 C  C   . SER B 2 192 ? 153.650 160.306 87.548  1.00 151.86 ? 192 SER H C   1 
ATOM   5657 O  O   . SER B 2 192 ? 153.315 161.331 86.947  1.00 151.86 ? 192 SER H O   1 
ATOM   5658 C  CB  . SER B 2 192 ? 151.875 158.558 87.358  1.00 151.86 ? 192 SER H CB  1 
ATOM   5659 O  OG  . SER B 2 192 ? 150.937 159.485 86.838  1.00 151.86 ? 192 SER H OG  1 
ATOM   5660 N  N   . THR B 2 193 ? 154.307 160.341 88.709  1.00 150.54 ? 193 THR H N   1 
ATOM   5661 C  CA  . THR B 2 193 ? 154.592 161.613 89.366  1.00 150.54 ? 193 THR H CA  1 
ATOM   5662 C  C   . THR B 2 193 ? 155.685 162.395 88.645  1.00 150.54 ? 193 THR H C   1 
ATOM   5663 O  O   . THR B 2 193 ? 155.591 163.621 88.517  1.00 150.54 ? 193 THR H O   1 
ATOM   5664 C  CB  . THR B 2 193 ? 154.985 161.374 90.824  1.00 150.54 ? 193 THR H CB  1 
ATOM   5665 O  OG1 . THR B 2 193 ? 154.126 160.380 91.395  1.00 150.54 ? 193 THR H OG1 1 
ATOM   5666 C  CG2 . THR B 2 193 ? 154.861 162.661 91.627  1.00 150.54 ? 193 THR H CG2 1 
ATOM   5667 N  N   . TRP B 2 194 ? 156.720 161.709 88.162  1.00 148.54 ? 194 TRP H N   1 
ATOM   5668 C  CA  . TRP B 2 194 ? 157.847 162.367 87.529  1.00 148.54 ? 194 TRP H CA  1 
ATOM   5669 C  C   . TRP B 2 194 ? 158.038 161.837 86.112  1.00 148.54 ? 194 TRP H C   1 
ATOM   5670 O  O   . TRP B 2 194 ? 157.921 160.628 85.887  1.00 148.54 ? 194 TRP H O   1 
ATOM   5671 C  CB  . TRP B 2 194 ? 159.133 162.142 88.347  1.00 148.54 ? 194 TRP H CB  1 
ATOM   5672 C  CG  . TRP B 2 194 ? 160.202 163.163 88.105  1.00 148.54 ? 194 TRP H CG  1 
ATOM   5673 C  CD1 . TRP B 2 194 ? 160.356 164.355 88.750  1.00 148.54 ? 194 TRP H CD1 1 
ATOM   5674 C  CD2 . TRP B 2 194 ? 161.267 163.084 87.150  1.00 148.54 ? 194 TRP H CD2 1 
ATOM   5675 N  NE1 . TRP B 2 194 ? 161.449 165.024 88.256  1.00 148.54 ? 194 TRP H NE1 1 
ATOM   5676 C  CE2 . TRP B 2 194 ? 162.025 164.265 87.271  1.00 148.54 ? 194 TRP H CE2 1 
ATOM   5677 C  CE3 . TRP B 2 194 ? 161.649 162.132 86.200  1.00 148.54 ? 194 TRP H CE3 1 
ATOM   5678 C  CZ2 . TRP B 2 194 ? 163.144 164.517 86.482  1.00 148.54 ? 194 TRP H CZ2 1 
ATOM   5679 C  CZ3 . TRP B 2 194 ? 162.761 162.383 85.418  1.00 148.54 ? 194 TRP H CZ3 1 
ATOM   5680 C  CH2 . TRP B 2 194 ? 163.495 163.566 85.565  1.00 148.54 ? 194 TRP H CH2 1 
ATOM   5681 N  N   . PRO B 2 195 ? 158.336 162.707 85.134  1.00 151.44 ? 195 PRO H N   1 
ATOM   5682 C  CA  . PRO B 2 195 ? 158.532 164.159 85.230  1.00 151.44 ? 195 PRO H CA  1 
ATOM   5683 C  C   . PRO B 2 195 ? 157.256 164.957 84.995  1.00 151.44 ? 195 PRO H C   1 
ATOM   5684 O  O   . PRO B 2 195 ? 157.311 166.073 84.485  1.00 151.44 ? 195 PRO H O   1 
ATOM   5685 C  CB  . PRO B 2 195 ? 159.575 164.419 84.139  1.00 151.44 ? 195 PRO H CB  1 
ATOM   5686 C  CG  . PRO B 2 195 ? 159.235 163.408 83.065  1.00 151.44 ? 195 PRO H CG  1 
ATOM   5687 C  CD  . PRO B 2 195 ? 158.579 162.226 83.762  1.00 151.44 ? 195 PRO H CD  1 
ATOM   5688 N  N   . SER B 2 196 ? 156.094 164.399 85.345  1.00 150.92 ? 196 SER H N   1 
ATOM   5689 C  CA  . SER B 2 196 ? 154.843 165.139 85.204  1.00 150.92 ? 196 SER H CA  1 
ATOM   5690 C  C   . SER B 2 196 ? 154.776 166.309 86.177  1.00 150.92 ? 196 SER H C   1 
ATOM   5691 O  O   . SER B 2 196 ? 154.318 167.399 85.815  1.00 150.92 ? 196 SER H O   1 
ATOM   5692 C  CB  . SER B 2 196 ? 153.654 164.205 85.411  1.00 150.92 ? 196 SER H CB  1 
ATOM   5693 O  OG  . SER B 2 196 ? 153.322 164.110 86.785  1.00 150.92 ? 196 SER H OG  1 
ATOM   5694 N  N   . GLN B 2 197 ? 155.226 166.105 87.411  1.00 147.61 ? 197 GLN H N   1 
ATOM   5695 C  CA  . GLN B 2 197 ? 155.212 167.146 88.430  1.00 147.61 ? 197 GLN H CA  1 
ATOM   5696 C  C   . GLN B 2 197 ? 156.620 167.698 88.609  1.00 147.61 ? 197 GLN H C   1 
ATOM   5697 O  O   . GLN B 2 197 ? 157.580 166.934 88.757  1.00 147.61 ? 197 GLN H O   1 
ATOM   5698 C  CB  . GLN B 2 197 ? 154.678 166.605 89.757  1.00 147.61 ? 197 GLN H CB  1 
ATOM   5699 C  CG  . GLN B 2 197 ? 153.959 167.645 90.605  1.00 147.61 ? 197 GLN H CG  1 
ATOM   5700 C  CD  . GLN B 2 197 ? 154.891 168.386 91.545  1.00 147.61 ? 197 GLN H CD  1 
ATOM   5701 O  OE1 . GLN B 2 197 ? 156.067 168.047 91.669  1.00 147.61 ? 197 GLN H OE1 1 
ATOM   5702 N  NE2 . GLN B 2 197 ? 154.367 169.409 92.211  1.00 147.61 ? 197 GLN H NE2 1 
ATOM   5703 N  N   . SER B 2 198 ? 156.737 169.023 88.591  1.00 143.69 ? 198 SER H N   1 
ATOM   5704 C  CA  . SER B 2 198 ? 158.025 169.691 88.757  1.00 143.69 ? 198 SER H CA  1 
ATOM   5705 C  C   . SER B 2 198 ? 158.449 169.592 90.216  1.00 143.69 ? 198 SER H C   1 
ATOM   5706 O  O   . SER B 2 198 ? 157.898 170.269 91.086  1.00 143.69 ? 198 SER H O   1 
ATOM   5707 C  CB  . SER B 2 198 ? 157.932 171.144 88.306  1.00 143.69 ? 198 SER H CB  1 
ATOM   5708 N  N   . ILE B 2 199 ? 159.432 168.742 90.490  1.00 139.44 ? 199 ILE H N   1 
ATOM   5709 C  CA  . ILE B 2 199 ? 159.940 168.545 91.842  1.00 139.44 ? 199 ILE H CA  1 
ATOM   5710 C  C   . ILE B 2 199 ? 161.218 169.355 92.006  1.00 139.44 ? 199 ILE H C   1 
ATOM   5711 O  O   . ILE B 2 199 ? 162.153 169.228 91.205  1.00 139.44 ? 199 ILE H O   1 
ATOM   5712 C  CB  . ILE B 2 199 ? 160.186 167.053 92.123  1.00 139.44 ? 199 ILE H CB  1 
ATOM   5713 C  CG1 . ILE B 2 199 ? 158.872 166.276 92.032  1.00 139.44 ? 199 ILE H CG1 1 
ATOM   5714 C  CG2 . ILE B 2 199 ? 160.823 166.862 93.490  1.00 139.44 ? 199 ILE H CG2 1 
ATOM   5715 C  CD1 . ILE B 2 199 ? 159.046 164.775 92.046  1.00 139.44 ? 199 ILE H CD1 1 
ATOM   5716 N  N   . THR B 2 200 ? 161.261 170.191 93.040  1.00 132.07 ? 200 THR H N   1 
ATOM   5717 C  CA  . THR B 2 200 ? 162.400 171.057 93.292  1.00 132.07 ? 200 THR H CA  1 
ATOM   5718 C  C   . THR B 2 200 ? 162.966 170.801 94.683  1.00 132.07 ? 200 THR H C   1 
ATOM   5719 O  O   . THR B 2 200 ? 162.288 170.279 95.573  1.00 132.07 ? 200 THR H O   1 
ATOM   5720 C  CB  . THR B 2 200 ? 162.024 172.537 93.148  1.00 132.07 ? 200 THR H CB  1 
ATOM   5721 O  OG1 . THR B 2 200 ? 163.183 173.348 93.374  1.00 132.07 ? 200 THR H OG1 1 
ATOM   5722 C  CG2 . THR B 2 200 ? 160.939 172.916 94.144  1.00 132.07 ? 200 THR H CG2 1 
ATOM   5723 N  N   . CYS B 2 201 ? 164.231 171.176 94.854  1.00 128.91 ? 201 CYS H N   1 
ATOM   5724 C  CA  . CYS B 2 201 ? 164.975 170.957 96.087  1.00 128.91 ? 201 CYS H CA  1 
ATOM   5725 C  C   . CYS B 2 201 ? 165.355 172.303 96.686  1.00 128.91 ? 201 CYS H C   1 
ATOM   5726 O  O   . CYS B 2 201 ? 165.944 173.145 96.000  1.00 128.91 ? 201 CYS H O   1 
ATOM   5727 C  CB  . CYS B 2 201 ? 166.223 170.111 95.813  1.00 128.91 ? 201 CYS H CB  1 
ATOM   5728 S  SG  . CYS B 2 201 ? 167.480 170.104 97.112  1.00 128.91 ? 201 CYS H SG  1 
ATOM   5729 N  N   . ASN B 2 202 ? 165.019 172.506 97.958  1.00 123.74 ? 202 ASN H N   1 
ATOM   5730 C  CA  . ASN B 2 202 ? 165.300 173.755 98.649  1.00 123.74 ? 202 ASN H CA  1 
ATOM   5731 C  C   . ASN B 2 202 ? 166.334 173.527 99.742  1.00 123.74 ? 202 ASN H C   1 
ATOM   5732 O  O   . ASN B 2 202 ? 166.477 172.417 100.264 1.00 123.74 ? 202 ASN H O   1 
ATOM   5733 C  CB  . ASN B 2 202 ? 164.032 174.363 99.262  1.00 123.74 ? 202 ASN H CB  1 
ATOM   5734 C  CG  . ASN B 2 202 ? 163.549 173.603 100.476 1.00 123.74 ? 202 ASN H CG  1 
ATOM   5735 O  OD1 . ASN B 2 202 ? 163.519 172.376 100.480 1.00 123.74 ? 202 ASN H OD1 1 
ATOM   5736 N  ND2 . ASN B 2 202 ? 163.173 174.332 101.520 1.00 123.74 ? 202 ASN H ND2 1 
ATOM   5737 N  N   . VAL B 2 203 ? 167.050 174.593 100.088 1.00 115.50 ? 203 VAL H N   1 
ATOM   5738 C  CA  . VAL B 2 203 ? 168.108 174.543 101.086 1.00 115.50 ? 203 VAL H CA  1 
ATOM   5739 C  C   . VAL B 2 203 ? 167.888 175.690 102.063 1.00 115.50 ? 203 VAL H C   1 
ATOM   5740 O  O   . VAL B 2 203 ? 167.217 176.677 101.747 1.00 115.50 ? 203 VAL H O   1 
ATOM   5741 C  CB  . VAL B 2 203 ? 169.508 174.612 100.421 1.00 115.50 ? 203 VAL H CB  1 
ATOM   5742 C  CG1 . VAL B 2 203 ? 169.826 176.027 99.943  1.00 115.50 ? 203 VAL H CG1 1 
ATOM   5743 C  CG2 . VAL B 2 203 ? 170.598 174.057 101.333 1.00 115.50 ? 203 VAL H CG2 1 
ATOM   5744 N  N   . ALA B 2 204 ? 168.428 175.544 103.273 1.00 109.25 ? 204 ALA H N   1 
ATOM   5745 C  CA  . ALA B 2 204 ? 168.331 176.582 104.300 1.00 109.25 ? 204 ALA H CA  1 
ATOM   5746 C  C   . ALA B 2 204 ? 169.613 176.553 105.126 1.00 109.25 ? 204 ALA H C   1 
ATOM   5747 O  O   . ALA B 2 204 ? 169.756 175.726 106.031 1.00 109.25 ? 204 ALA H O   1 
ATOM   5748 C  CB  . ALA B 2 204 ? 167.101 176.381 105.177 1.00 109.25 ? 204 ALA H CB  1 
ATOM   5749 N  N   . HIS B 2 205 ? 170.538 177.456 104.813 1.00 102.97 ? 205 HIS H N   1 
ATOM   5750 C  CA  . HIS B 2 205 ? 171.791 177.567 105.550 1.00 102.97 ? 205 HIS H CA  1 
ATOM   5751 C  C   . HIS B 2 205 ? 171.752 178.809 106.427 1.00 102.97 ? 205 HIS H C   1 
ATOM   5752 O  O   . HIS B 2 205 ? 171.754 179.933 105.899 1.00 102.97 ? 205 HIS H O   1 
ATOM   5753 C  CB  . HIS B 2 205 ? 172.980 177.621 104.591 1.00 102.97 ? 205 HIS H CB  1 
ATOM   5754 C  CG  . HIS B 2 205 ? 174.309 177.474 105.265 1.00 102.97 ? 205 HIS H CG  1 
ATOM   5755 N  ND1 . HIS B 2 205 ? 175.499 177.760 104.633 1.00 102.97 ? 205 HIS H ND1 1 
ATOM   5756 C  CD2 . HIS B 2 205 ? 174.634 177.084 106.520 1.00 102.97 ? 205 HIS H CD2 1 
ATOM   5757 C  CE1 . HIS B 2 205 ? 176.501 177.543 105.465 1.00 102.97 ? 205 HIS H CE1 1 
ATOM   5758 N  NE2 . HIS B 2 205 ? 176.004 177.132 106.617 1.00 102.97 ? 205 HIS H NE2 1 
ATOM   5759 N  N   . PRO B 2 206 ? 171.709 178.667 107.755 1.00 102.97 ? 206 PRO H N   1 
ATOM   5760 C  CA  . PRO B 2 206 ? 171.583 179.857 108.610 1.00 102.97 ? 206 PRO H CA  1 
ATOM   5761 C  C   . PRO B 2 206 ? 172.851 180.686 108.694 1.00 102.97 ? 206 PRO H C   1 
ATOM   5762 O  O   . PRO B 2 206 ? 172.764 181.912 108.833 1.00 102.97 ? 206 PRO H O   1 
ATOM   5763 C  CB  . PRO B 2 206 ? 171.205 179.272 109.980 1.00 102.97 ? 206 PRO H CB  1 
ATOM   5764 C  CG  . PRO B 2 206 ? 170.884 177.817 109.733 1.00 102.97 ? 206 PRO H CG  1 
ATOM   5765 C  CD  . PRO B 2 206 ? 171.677 177.422 108.535 1.00 102.97 ? 206 PRO H CD  1 
ATOM   5766 N  N   . ALA B 2 207 ? 174.026 180.063 108.613 1.00 101.39 ? 207 ALA H N   1 
ATOM   5767 C  CA  . ALA B 2 207 ? 175.276 180.796 108.764 1.00 101.39 ? 207 ALA H CA  1 
ATOM   5768 C  C   . ALA B 2 207 ? 175.690 181.543 107.505 1.00 101.39 ? 207 ALA H C   1 
ATOM   5769 O  O   . ALA B 2 207 ? 176.614 182.361 107.568 1.00 101.39 ? 207 ALA H O   1 
ATOM   5770 C  CB  . ALA B 2 207 ? 176.395 179.845 109.185 1.00 101.39 ? 207 ALA H CB  1 
ATOM   5771 N  N   . SER B 2 208 ? 175.043 181.285 106.370 1.00 106.23 ? 208 SER H N   1 
ATOM   5772 C  CA  . SER B 2 208 ? 175.330 182.008 105.142 1.00 106.23 ? 208 SER H CA  1 
ATOM   5773 C  C   . SER B 2 208 ? 174.107 182.696 104.554 1.00 106.23 ? 208 SER H C   1 
ATOM   5774 O  O   . SER B 2 208 ? 174.254 183.436 103.574 1.00 106.23 ? 208 SER H O   1 
ATOM   5775 C  CB  . SER B 2 208 ? 175.937 181.067 104.091 1.00 106.23 ? 208 SER H CB  1 
ATOM   5776 O  OG  . SER B 2 208 ? 176.059 181.713 102.836 1.00 106.23 ? 208 SER H OG  1 
ATOM   5777 N  N   . SER B 2 209 ? 172.917 182.475 105.128 1.00 110.04 ? 209 SER H N   1 
ATOM   5778 C  CA  . SER B 2 209 ? 171.655 183.082 104.686 1.00 110.04 ? 209 SER H CA  1 
ATOM   5779 C  C   . SER B 2 209 ? 171.365 182.784 103.215 1.00 110.04 ? 209 SER H C   1 
ATOM   5780 O  O   . SER B 2 209 ? 170.931 183.654 102.458 1.00 110.04 ? 209 SER H O   1 
ATOM   5781 C  CB  . SER B 2 209 ? 171.639 184.591 104.951 1.00 110.04 ? 209 SER H CB  1 
ATOM   5782 O  OG  . SER B 2 209 ? 171.903 184.869 106.315 1.00 110.04 ? 209 SER H OG  1 
ATOM   5783 N  N   . THR B 2 210 ? 171.609 181.542 102.808 1.00 111.80 ? 210 THR H N   1 
ATOM   5784 C  CA  . THR B 2 210 ? 171.431 181.133 101.422 1.00 111.80 ? 210 THR H CA  1 
ATOM   5785 C  C   . THR B 2 210 ? 170.103 180.405 101.260 1.00 111.80 ? 210 THR H C   1 
ATOM   5786 O  O   . THR B 2 210 ? 169.765 179.528 102.061 1.00 111.80 ? 210 THR H O   1 
ATOM   5787 C  CB  . THR B 2 210 ? 172.585 180.236 100.975 1.00 111.80 ? 210 THR H CB  1 
ATOM   5788 O  OG1 . THR B 2 210 ? 173.826 180.796 101.425 1.00 111.80 ? 210 THR H OG1 1 
ATOM   5789 C  CG2 . THR B 2 210 ? 172.612 180.116 99.458  1.00 111.80 ? 210 THR H CG2 1 
ATOM   5790 N  N   . LYS B 2 211 ? 169.352 180.776 100.220 1.00 118.28 ? 211 LYS H N   1 
ATOM   5791 C  CA  . LYS B 2 211 ? 168.055 180.166 99.914  1.00 118.28 ? 211 LYS H CA  1 
ATOM   5792 C  C   . LYS B 2 211 ? 167.938 180.076 98.393  1.00 118.28 ? 211 LYS H C   1 
ATOM   5793 O  O   . LYS B 2 211 ? 167.583 181.054 97.728  1.00 118.28 ? 211 LYS H O   1 
ATOM   5794 C  CB  . LYS B 2 211 ? 166.911 180.966 100.524 1.00 118.28 ? 211 LYS H CB  1 
ATOM   5795 C  CG  . LYS B 2 211 ? 165.527 180.402 100.237 1.00 118.28 ? 211 LYS H CG  1 
ATOM   5796 C  CD  . LYS B 2 211 ? 165.216 179.206 101.118 1.00 118.28 ? 211 LYS H CD  1 
ATOM   5797 C  CE  . LYS B 2 211 ? 165.263 179.578 102.592 1.00 118.28 ? 211 LYS H CE  1 
ATOM   5798 N  NZ  . LYS B 2 211 ? 164.178 180.527 102.964 1.00 118.28 ? 211 LYS H NZ  1 
ATOM   5799 N  N   . VAL B 2 212 ? 168.251 178.903 97.846  1.00 120.41 ? 212 VAL H N   1 
ATOM   5800 C  CA  . VAL B 2 212 ? 168.156 178.644 96.415  1.00 120.41 ? 212 VAL H CA  1 
ATOM   5801 C  C   . VAL B 2 212 ? 167.335 177.379 96.197  1.00 120.41 ? 212 VAL H C   1 
ATOM   5802 O  O   . VAL B 2 212 ? 167.368 176.455 97.018  1.00 120.41 ? 212 VAL H O   1 
ATOM   5803 C  CB  . VAL B 2 212 ? 169.548 178.525 95.752  1.00 120.41 ? 212 VAL H CB  1 
ATOM   5804 C  CG1 . VAL B 2 212 ? 170.291 179.850 95.824  1.00 120.41 ? 212 VAL H CG1 1 
ATOM   5805 C  CG2 . VAL B 2 212 ? 170.373 177.440 96.417  1.00 120.41 ? 212 VAL H CG2 1 
ATOM   5806 N  N   . ASP B 2 213 ? 166.572 177.354 95.107  1.00 124.18 ? 213 ASP H N   1 
ATOM   5807 C  CA  . ASP B 2 213 ? 165.744 176.211 94.740  1.00 124.18 ? 213 ASP H CA  1 
ATOM   5808 C  C   . ASP B 2 213 ? 166.125 175.740 93.344  1.00 124.18 ? 213 ASP H C   1 
ATOM   5809 O  O   . ASP B 2 213 ? 166.195 176.547 92.410  1.00 124.18 ? 213 ASP H O   1 
ATOM   5810 C  CB  . ASP B 2 213 ? 164.257 176.567 94.785  1.00 124.18 ? 213 ASP H CB  1 
ATOM   5811 C  CG  . ASP B 2 213 ? 163.823 177.103 96.134  1.00 124.18 ? 213 ASP H CG  1 
ATOM   5812 O  OD1 . ASP B 2 213 ? 164.475 176.779 97.146  1.00 124.18 ? 213 ASP H OD1 1 
ATOM   5813 O  OD2 . ASP B 2 213 ? 162.824 177.849 96.183  1.00 124.18 ? 213 ASP H OD2 1 
ATOM   5814 N  N   . LYS B 2 214 ? 166.365 174.437 93.202  1.00 125.84 ? 214 LYS H N   1 
ATOM   5815 C  CA  . LYS B 2 214 ? 166.794 173.843 91.943  1.00 125.84 ? 214 LYS H CA  1 
ATOM   5816 C  C   . LYS B 2 214 ? 165.850 172.714 91.555  1.00 125.84 ? 214 LYS H C   1 
ATOM   5817 O  O   . LYS B 2 214 ? 165.506 171.872 92.391  1.00 125.84 ? 214 LYS H O   1 
ATOM   5818 C  CB  . LYS B 2 214 ? 168.230 173.314 92.040  1.00 125.84 ? 214 LYS H CB  1 
ATOM   5819 C  CG  . LYS B 2 214 ? 169.228 174.286 92.650  1.00 125.84 ? 214 LYS H CG  1 
ATOM   5820 C  CD  . LYS B 2 214 ? 169.701 175.307 91.630  1.00 125.84 ? 214 LYS H CD  1 
ATOM   5821 C  CE  . LYS B 2 214 ? 170.383 174.630 90.452  1.00 125.84 ? 214 LYS H CE  1 
ATOM   5822 N  NZ  . LYS B 2 214 ? 170.288 175.435 89.204  1.00 125.84 ? 214 LYS H NZ  1 
ATOM   5823 N  N   . LYS B 2 215 ? 165.436 172.703 90.291  1.00 129.75 ? 215 LYS H N   1 
ATOM   5824 C  CA  . LYS B 2 215 ? 164.674 171.609 89.705  1.00 129.75 ? 215 LYS H CA  1 
ATOM   5825 C  C   . LYS B 2 215 ? 165.352 171.180 88.412  1.00 129.75 ? 215 LYS H C   1 
ATOM   5826 O  O   . LYS B 2 215 ? 165.790 172.023 87.622  1.00 129.75 ? 215 LYS H O   1 
ATOM   5827 C  CB  . LYS B 2 215 ? 163.224 172.018 89.432  1.00 129.75 ? 215 LYS H CB  1 
ATOM   5828 N  N   . ILE B 2 216 ? 165.433 169.870 88.193  1.00 135.34 ? 216 ILE H N   1 
ATOM   5829 C  CA  . ILE B 2 216 ? 166.235 169.315 87.111  1.00 135.34 ? 216 ILE H CA  1 
ATOM   5830 C  C   . ILE B 2 216 ? 165.310 168.699 86.067  1.00 135.34 ? 216 ILE H C   1 
ATOM   5831 O  O   . ILE B 2 216 ? 164.184 168.288 86.365  1.00 135.34 ? 216 ILE H O   1 
ATOM   5832 C  CB  . ILE B 2 216 ? 167.263 168.282 87.650  1.00 135.34 ? 216 ILE H CB  1 
ATOM   5833 C  CG1 . ILE B 2 216 ? 168.382 168.012 86.637  1.00 135.34 ? 216 ILE H CG1 1 
ATOM   5834 C  CG2 . ILE B 2 216 ? 166.581 166.982 88.056  1.00 135.34 ? 216 ILE H CG2 1 
ATOM   5835 C  CD1 . ILE B 2 216 ? 169.273 169.206 86.375  1.00 135.34 ? 216 ILE H CD1 1 
ATOM   5836 N  N   . GLU B 2 217 ? 165.782 168.685 84.818  1.00 139.87 ? 217 GLU H N   1 
ATOM   5837 C  CA  . GLU B 2 217 ? 165.151 168.038 83.683  1.00 139.87 ? 217 GLU H CA  1 
ATOM   5838 C  C   . GLU B 2 217 ? 165.908 166.762 83.321  1.00 139.87 ? 217 GLU H C   1 
ATOM   5839 O  O   . GLU B 2 217 ? 167.122 166.679 83.531  1.00 139.87 ? 217 GLU H O   1 
ATOM   5840 C  CB  . GLU B 2 217 ? 165.118 168.975 82.468  1.00 139.87 ? 217 GLU H CB  1 
ATOM   5841 N  N   . PRO B 2 218 ? 165.224 165.742 82.784  1.00 145.46 ? 218 PRO H N   1 
ATOM   5842 C  CA  . PRO B 2 218 ? 165.921 164.493 82.446  1.00 145.46 ? 218 PRO H CA  1 
ATOM   5843 C  C   . PRO B 2 218 ? 166.836 164.633 81.240  1.00 145.46 ? 218 PRO H C   1 
ATOM   5844 O  O   . PRO B 2 218 ? 166.465 164.273 80.119  1.00 145.46 ? 218 PRO H O   1 
ATOM   5845 C  CB  . PRO B 2 218 ? 164.774 163.512 82.170  1.00 145.46 ? 218 PRO H CB  1 
ATOM   5846 C  CG  . PRO B 2 218 ? 163.619 164.372 81.794  1.00 145.46 ? 218 PRO H CG  1 
ATOM   5847 C  CD  . PRO B 2 218 ? 163.766 165.627 82.600  1.00 145.46 ? 218 PRO H CD  1 
ATOM   5848 N  N   . ARG B 2 219 ? 168.035 165.160 81.463  1.00 143.51 ? 219 ARG H N   1 
ATOM   5849 C  CA  . ARG B 2 219 ? 169.018 165.302 80.397  1.00 143.51 ? 219 ARG H CA  1 
ATOM   5850 C  C   . ARG B 2 219 ? 169.747 163.984 80.154  1.00 143.51 ? 219 ARG H C   1 
ATOM   5851 O  O   . ARG B 2 219 ? 169.887 163.165 81.063  1.00 143.51 ? 219 ARG H O   1 
ATOM   5852 C  CB  . ARG B 2 219 ? 170.021 166.407 80.734  1.00 143.51 ? 219 ARG H CB  1 
ATOM   5853 N  N   . GLU C 3 1   ? 185.430 162.174 139.866 1.00 78.20  ? 1   GLU L N   1 
ATOM   5854 C  CA  . GLU C 3 1   ? 185.249 161.579 138.549 1.00 78.20  ? 1   GLU L CA  1 
ATOM   5855 C  C   . GLU C 3 1   ? 184.850 160.113 138.661 1.00 78.20  ? 1   GLU L C   1 
ATOM   5856 O  O   . GLU C 3 1   ? 185.694 159.221 138.583 1.00 78.20  ? 1   GLU L O   1 
ATOM   5857 C  CB  . GLU C 3 1   ? 186.525 161.714 137.716 1.00 78.20  ? 1   GLU L CB  1 
ATOM   5858 C  CG  . GLU C 3 1   ? 186.338 161.404 136.241 1.00 78.20  ? 1   GLU L CG  1 
ATOM   5859 C  CD  . GLU C 3 1   ? 185.747 162.564 135.471 1.00 78.20  ? 1   GLU L CD  1 
ATOM   5860 O  OE1 . GLU C 3 1   ? 185.951 163.720 135.894 1.00 78.20  ? 1   GLU L OE1 1 
ATOM   5861 O  OE2 . GLU C 3 1   ? 185.075 162.320 134.447 1.00 78.20  ? 1   GLU L OE2 1 
ATOM   5862 N  N   . ASN C 3 2   ? 183.556 159.869 138.853 1.00 81.38  ? 2   ASN L N   1 
ATOM   5863 C  CA  . ASN C 3 2   ? 183.027 158.509 138.902 1.00 81.38  ? 2   ASN L CA  1 
ATOM   5864 C  C   . ASN C 3 2   ? 182.791 158.071 137.463 1.00 81.38  ? 2   ASN L C   1 
ATOM   5865 O  O   . ASN C 3 2   ? 181.727 158.298 136.885 1.00 81.38  ? 2   ASN L O   1 
ATOM   5866 C  CB  . ASN C 3 2   ? 181.751 158.455 139.735 1.00 81.38  ? 2   ASN L CB  1 
ATOM   5867 C  CG  . ASN C 3 2   ? 181.311 157.034 140.048 1.00 81.38  ? 2   ASN L CG  1 
ATOM   5868 O  OD1 . ASN C 3 2   ? 181.948 156.064 139.636 1.00 81.38  ? 2   ASN L OD1 1 
ATOM   5869 N  ND2 . ASN C 3 2   ? 180.213 156.907 140.786 1.00 81.38  ? 2   ASN L ND2 1 
ATOM   5870 N  N   . VAL C 3 3   ? 183.807 157.442 136.877 1.00 82.39  ? 3   VAL L N   1 
ATOM   5871 C  CA  . VAL C 3 3   ? 183.782 157.070 135.464 1.00 82.39  ? 3   VAL L CA  1 
ATOM   5872 C  C   . VAL C 3 3   ? 182.789 155.927 135.279 1.00 82.39  ? 3   VAL L C   1 
ATOM   5873 O  O   . VAL C 3 3   ? 183.051 154.791 135.682 1.00 82.39  ? 3   VAL L O   1 
ATOM   5874 C  CB  . VAL C 3 3   ? 185.175 156.677 134.962 1.00 82.39  ? 3   VAL L CB  1 
ATOM   5875 C  CG1 . VAL C 3 3   ? 185.115 156.281 133.495 1.00 82.39  ? 3   VAL L CG1 1 
ATOM   5876 C  CG2 . VAL C 3 3   ? 186.153 157.819 135.171 1.00 82.39  ? 3   VAL L CG2 1 
ATOM   5877 N  N   . LEU C 3 4   ? 181.650 156.226 134.666 1.00 76.38  ? 4   LEU L N   1 
ATOM   5878 C  CA  . LEU C 3 4   ? 180.628 155.231 134.385 1.00 76.38  ? 4   LEU L CA  1 
ATOM   5879 C  C   . LEU C 3 4   ? 180.870 154.639 133.004 1.00 76.38  ? 4   LEU L C   1 
ATOM   5880 O  O   . LEU C 3 4   ? 181.192 155.367 132.060 1.00 76.38  ? 4   LEU L O   1 
ATOM   5881 C  CB  . LEU C 3 4   ? 179.230 155.844 134.459 1.00 76.38  ? 4   LEU L CB  1 
ATOM   5882 C  CG  . LEU C 3 4   ? 178.830 156.468 135.794 1.00 76.38  ? 4   LEU L CG  1 
ATOM   5883 C  CD1 . LEU C 3 4   ? 177.846 157.598 135.575 1.00 76.38  ? 4   LEU L CD1 1 
ATOM   5884 C  CD2 . LEU C 3 4   ? 178.229 155.417 136.700 1.00 76.38  ? 4   LEU L CD2 1 
ATOM   5885 N  N   . THR C 3 5   ? 180.722 153.323 132.894 1.00 76.86  ? 5   THR L N   1 
ATOM   5886 C  CA  . THR C 3 5   ? 180.841 152.629 131.623 1.00 76.86  ? 5   THR L CA  1 
ATOM   5887 C  C   . THR C 3 5   ? 179.596 151.784 131.398 1.00 76.86  ? 5   THR L C   1 
ATOM   5888 O  O   . THR C 3 5   ? 178.898 151.413 132.345 1.00 76.86  ? 5   THR L O   1 
ATOM   5889 C  CB  . THR C 3 5   ? 182.106 151.753 131.565 1.00 76.86  ? 5   THR L CB  1 
ATOM   5890 O  OG1 . THR C 3 5   ? 182.250 151.203 130.251 1.00 76.86  ? 5   THR L OG1 1 
ATOM   5891 C  CG2 . THR C 3 5   ? 182.042 150.626 132.586 1.00 76.86  ? 5   THR L CG2 1 
ATOM   5892 N  N   . GLN C 3 6   ? 179.306 151.509 130.131 1.00 74.40  ? 6   GLN L N   1 
ATOM   5893 C  CA  . GLN C 3 6   ? 178.130 150.740 129.754 1.00 74.40  ? 6   GLN L CA  1 
ATOM   5894 C  C   . GLN C 3 6   ? 178.514 149.686 128.729 1.00 74.40  ? 6   GLN L C   1 
ATOM   5895 O  O   . GLN C 3 6   ? 179.335 149.938 127.842 1.00 74.40  ? 6   GLN L O   1 
ATOM   5896 C  CB  . GLN C 3 6   ? 177.028 151.643 129.192 1.00 74.40  ? 6   GLN L CB  1 
ATOM   5897 C  CG  . GLN C 3 6   ? 176.435 152.597 130.210 1.00 74.40  ? 6   GLN L CG  1 
ATOM   5898 C  CD  . GLN C 3 6   ? 175.337 153.459 129.630 1.00 74.40  ? 6   GLN L CD  1 
ATOM   5899 O  OE1 . GLN C 3 6   ? 175.039 153.388 128.442 1.00 74.40  ? 6   GLN L OE1 1 
ATOM   5900 N  NE2 . GLN C 3 6   ? 174.725 154.277 130.471 1.00 74.40  ? 6   GLN L NE2 1 
ATOM   5901 N  N   . SER C 3 7   ? 177.916 148.504 128.859 1.00 78.17  ? 7   SER L N   1 
ATOM   5902 C  CA  . SER C 3 7   ? 178.188 147.391 127.969 1.00 78.17  ? 7   SER L CA  1 
ATOM   5903 C  C   . SER C 3 7   ? 176.898 146.647 127.652 1.00 78.17  ? 7   SER L C   1 
ATOM   5904 O  O   . SER C 3 7   ? 176.100 146.374 128.556 1.00 78.17  ? 7   SER L O   1 
ATOM   5905 C  CB  . SER C 3 7   ? 179.201 146.424 128.597 1.00 78.17  ? 7   SER L CB  1 
ATOM   5906 O  OG  . SER C 3 7   ? 178.786 146.023 129.891 1.00 78.17  ? 7   SER L OG  1 
ATOM   5907 N  N   . PRO C 3 8   ? 176.659 146.309 126.380 1.00 80.80  ? 8   PRO L N   1 
ATOM   5908 C  CA  . PRO C 3 8   ? 177.446 146.658 125.191 1.00 80.80  ? 8   PRO L CA  1 
ATOM   5909 C  C   . PRO C 3 8   ? 177.095 148.048 124.673 1.00 80.80  ? 8   PRO L C   1 
ATOM   5910 O  O   . PRO C 3 8   ? 176.018 148.562 124.961 1.00 80.80  ? 8   PRO L O   1 
ATOM   5911 C  CB  . PRO C 3 8   ? 177.063 145.555 124.200 1.00 80.80  ? 8   PRO L CB  1 
ATOM   5912 C  CG  . PRO C 3 8   ? 175.634 145.243 124.546 1.00 80.80  ? 8   PRO L CG  1 
ATOM   5913 C  CD  . PRO C 3 8   ? 175.520 145.437 126.043 1.00 80.80  ? 8   PRO L CD  1 
ATOM   5914 N  N   . ALA C 3 9   ? 177.994 148.680 123.914 1.00 84.05  ? 9   ALA L N   1 
ATOM   5915 C  CA  . ALA C 3 9   ? 177.703 150.002 123.368 1.00 84.05  ? 9   ALA L CA  1 
ATOM   5916 C  C   . ALA C 3 9   ? 176.642 149.929 122.277 1.00 84.05  ? 9   ALA L C   1 
ATOM   5917 O  O   . ALA C 3 9   ? 175.837 150.854 122.121 1.00 84.05  ? 9   ALA L O   1 
ATOM   5918 C  CB  . ALA C 3 9   ? 178.982 150.644 122.833 1.00 84.05  ? 9   ALA L CB  1 
ATOM   5919 N  N   . ILE C 3 10  ? 176.626 148.840 121.515 1.00 88.28  ? 10  ILE L N   1 
ATOM   5920 C  CA  . ILE C 3 10  ? 175.654 148.628 120.452 1.00 88.28  ? 10  ILE L CA  1 
ATOM   5921 C  C   . ILE C 3 10  ? 174.949 147.298 120.694 1.00 88.28  ? 10  ILE L C   1 
ATOM   5922 O  O   . ILE C 3 10  ? 175.585 146.295 121.038 1.00 88.28  ? 10  ILE L O   1 
ATOM   5923 C  CB  . ILE C 3 10  ? 176.323 148.686 119.057 1.00 88.28  ? 10  ILE L CB  1 
ATOM   5924 C  CG1 . ILE C 3 10  ? 175.298 148.490 117.935 1.00 88.28  ? 10  ILE L CG1 1 
ATOM   5925 C  CG2 . ILE C 3 10  ? 177.510 147.724 118.947 1.00 88.28  ? 10  ILE L CG2 1 
ATOM   5926 C  CD1 . ILE C 3 10  ? 174.148 149.465 117.977 1.00 88.28  ? 10  ILE L CD1 1 
ATOM   5927 N  N   . MET C 3 11  ? 173.625 147.307 120.566 1.00 90.87  ? 11  MET L N   1 
ATOM   5928 C  CA  . MET C 3 11  ? 172.827 146.102 120.733 1.00 90.87  ? 11  MET L CA  1 
ATOM   5929 C  C   . MET C 3 11  ? 171.603 146.205 119.837 1.00 90.87  ? 11  MET L C   1 
ATOM   5930 O  O   . MET C 3 11  ? 171.161 147.300 119.486 1.00 90.87  ? 11  MET L O   1 
ATOM   5931 C  CB  . MET C 3 11  ? 172.417 145.896 122.197 1.00 90.87  ? 11  MET L CB  1 
ATOM   5932 C  CG  . MET C 3 11  ? 171.246 146.755 122.641 1.00 90.87  ? 11  MET L CG  1 
ATOM   5933 S  SD  . MET C 3 11  ? 170.524 146.227 124.200 1.00 90.87  ? 11  MET L SD  1 
ATOM   5934 C  CE  . MET C 3 11  ? 171.989 146.051 125.206 1.00 90.87  ? 11  MET L CE  1 
ATOM   5935 N  N   . SER C 3 12  ? 171.061 145.049 119.463 1.00 97.32  ? 12  SER L N   1 
ATOM   5936 C  CA  . SER C 3 12  ? 169.883 144.981 118.609 1.00 97.32  ? 12  SER L CA  1 
ATOM   5937 C  C   . SER C 3 12  ? 168.887 144.006 119.214 1.00 97.32  ? 12  SER L C   1 
ATOM   5938 O  O   . SER C 3 12  ? 169.261 142.897 119.606 1.00 97.32  ? 12  SER L O   1 
ATOM   5939 C  CB  . SER C 3 12  ? 170.249 144.553 117.186 1.00 97.32  ? 12  SER L CB  1 
ATOM   5940 O  OG  . SER C 3 12  ? 169.093 144.453 116.374 1.00 97.32  ? 12  SER L OG  1 
ATOM   5941 N  N   . THR C 3 13  ? 167.624 144.420 119.294 1.00 99.37  ? 13  THR L N   1 
ATOM   5942 C  CA  . THR C 3 13  ? 166.566 143.624 119.902 1.00 99.37  ? 13  THR L CA  1 
ATOM   5943 C  C   . THR C 3 13  ? 165.395 143.493 118.941 1.00 99.37  ? 13  THR L C   1 
ATOM   5944 O  O   . THR C 3 13  ? 164.950 144.488 118.360 1.00 99.37  ? 13  THR L O   1 
ATOM   5945 C  CB  . THR C 3 13  ? 166.075 144.247 121.211 1.00 99.37  ? 13  THR L CB  1 
ATOM   5946 O  OG1 . THR C 3 13  ? 165.514 145.538 120.944 1.00 99.37  ? 13  THR L OG1 1 
ATOM   5947 C  CG2 . THR C 3 13  ? 167.212 144.390 122.202 1.00 99.37  ? 13  THR L CG2 1 
ATOM   5948 N  N   . SER C 3 14  ? 164.901 142.270 118.779 1.00 99.09  ? 14  SER L N   1 
ATOM   5949 C  CA  . SER C 3 14  ? 163.630 142.069 118.109 1.00 99.09  ? 14  SER L CA  1 
ATOM   5950 C  C   . SER C 3 14  ? 162.493 142.532 119.022 1.00 99.09  ? 14  SER L C   1 
ATOM   5951 O  O   . SER C 3 14  ? 162.643 142.538 120.246 1.00 99.09  ? 14  SER L O   1 
ATOM   5952 C  CB  . SER C 3 14  ? 163.448 140.598 117.742 1.00 99.09  ? 14  SER L CB  1 
ATOM   5953 O  OG  . SER C 3 14  ? 164.250 140.249 116.628 1.00 99.09  ? 14  SER L OG  1 
ATOM   5954 N  N   . PRO C 3 15  ? 161.363 142.957 118.451 1.00 94.36  ? 15  PRO L N   1 
ATOM   5955 C  CA  . PRO C 3 15  ? 160.228 143.377 119.287 1.00 94.36  ? 15  PRO L CA  1 
ATOM   5956 C  C   . PRO C 3 15  ? 159.689 142.235 120.137 1.00 94.36  ? 15  PRO L C   1 
ATOM   5957 O  O   . PRO C 3 15  ? 159.672 141.076 119.719 1.00 94.36  ? 15  PRO L O   1 
ATOM   5958 C  CB  . PRO C 3 15  ? 159.188 143.853 118.267 1.00 94.36  ? 15  PRO L CB  1 
ATOM   5959 C  CG  . PRO C 3 15  ? 159.956 144.176 117.044 1.00 94.36  ? 15  PRO L CG  1 
ATOM   5960 C  CD  . PRO C 3 15  ? 161.158 143.286 117.028 1.00 94.36  ? 15  PRO L CD  1 
ATOM   5961 N  N   . GLY C 3 16  ? 159.244 142.580 121.341 1.00 97.78  ? 16  GLY L N   1 
ATOM   5962 C  CA  . GLY C 3 16  ? 158.734 141.595 122.280 1.00 97.78  ? 16  GLY L CA  1 
ATOM   5963 C  C   . GLY C 3 16  ? 159.771 140.619 122.793 1.00 97.78  ? 16  GLY L C   1 
ATOM   5964 O  O   . GLY C 3 16  ? 159.504 139.413 122.852 1.00 97.78  ? 16  GLY L O   1 
ATOM   5965 N  N   . GLU C 3 17  ? 160.951 141.109 123.165 1.00 99.81  ? 17  GLU L N   1 
ATOM   5966 C  CA  . GLU C 3 17  ? 162.039 140.258 123.619 1.00 99.81  ? 17  GLU L CA  1 
ATOM   5967 C  C   . GLU C 3 17  ? 162.624 140.817 124.909 1.00 99.81  ? 17  GLU L C   1 
ATOM   5968 O  O   . GLU C 3 17  ? 162.623 142.030 125.135 1.00 99.81  ? 17  GLU L O   1 
ATOM   5969 C  CB  . GLU C 3 17  ? 163.132 140.143 122.543 1.00 99.81  ? 17  GLU L CB  1 
ATOM   5970 C  CG  . GLU C 3 17  ? 164.119 139.007 122.756 1.00 99.81  ? 17  GLU L CG  1 
ATOM   5971 C  CD  . GLU C 3 17  ? 165.365 139.157 121.910 1.00 99.81  ? 17  GLU L CD  1 
ATOM   5972 O  OE1 . GLU C 3 17  ? 166.332 139.788 122.383 1.00 99.81  ? 17  GLU L OE1 1 
ATOM   5973 O  OE2 . GLU C 3 17  ? 165.377 138.646 120.771 1.00 99.81  ? 17  GLU L OE2 1 
ATOM   5974 N  N   . LYS C 3 18  ? 163.106 139.913 125.762 1.00 98.03  ? 18  LYS L N   1 
ATOM   5975 C  CA  . LYS C 3 18  ? 163.778 140.312 126.992 1.00 98.03  ? 18  LYS L CA  1 
ATOM   5976 C  C   . LYS C 3 18  ? 165.079 141.041 126.679 1.00 98.03  ? 18  LYS L C   1 
ATOM   5977 O  O   . LYS C 3 18  ? 165.833 140.642 125.788 1.00 98.03  ? 18  LYS L O   1 
ATOM   5978 C  CB  . LYS C 3 18  ? 164.073 139.085 127.859 1.00 98.03  ? 18  LYS L CB  1 
ATOM   5979 C  CG  . LYS C 3 18  ? 162.871 138.244 128.327 1.00 98.03  ? 18  LYS L CG  1 
ATOM   5980 C  CD  . LYS C 3 18  ? 162.028 138.907 129.421 1.00 98.03  ? 18  LYS L CD  1 
ATOM   5981 C  CE  . LYS C 3 18  ? 160.799 139.622 128.880 1.00 98.03  ? 18  LYS L CE  1 
ATOM   5982 N  NZ  . LYS C 3 18  ? 159.940 140.170 129.965 1.00 98.03  ? 18  LYS L NZ  1 
ATOM   5983 N  N   . VAL C 3 19  ? 165.342 142.113 127.421 1.00 91.21  ? 19  VAL L N   1 
ATOM   5984 C  CA  . VAL C 3 19  ? 166.560 142.898 127.243 1.00 91.21  ? 19  VAL L CA  1 
ATOM   5985 C  C   . VAL C 3 19  ? 166.898 143.579 128.565 1.00 91.21  ? 19  VAL L C   1 
ATOM   5986 O  O   . VAL C 3 19  ? 166.010 144.011 129.307 1.00 91.21  ? 19  VAL L O   1 
ATOM   5987 C  CB  . VAL C 3 19  ? 166.409 143.899 126.072 1.00 91.21  ? 19  VAL L CB  1 
ATOM   5988 C  CG1 . VAL C 3 19  ? 165.285 144.884 126.320 1.00 91.21  ? 19  VAL L CG1 1 
ATOM   5989 C  CG2 . VAL C 3 19  ? 167.710 144.639 125.819 1.00 91.21  ? 19  VAL L CG2 1 
ATOM   5990 N  N   . THR C 3 20  ? 168.193 143.637 128.875 1.00 82.49  ? 20  THR L N   1 
ATOM   5991 C  CA  . THR C 3 20  ? 168.665 144.252 130.113 1.00 82.49  ? 20  THR L CA  1 
ATOM   5992 C  C   . THR C 3 20  ? 170.002 144.923 129.834 1.00 82.49  ? 20  THR L C   1 
ATOM   5993 O  O   . THR C 3 20  ? 170.980 144.245 129.506 1.00 82.49  ? 20  THR L O   1 
ATOM   5994 C  CB  . THR C 3 20  ? 168.797 143.214 131.225 1.00 82.49  ? 20  THR L CB  1 
ATOM   5995 O  OG1 . THR C 3 20  ? 167.503 142.693 131.552 1.00 82.49  ? 20  THR L OG1 1 
ATOM   5996 C  CG2 . THR C 3 20  ? 169.420 143.835 132.466 1.00 82.49  ? 20  THR L CG2 1 
ATOM   5997 N  N   . MET C 3 21  ? 170.042 146.247 129.957 1.00 77.64  ? 21  MET L N   1 
ATOM   5998 C  CA  . MET C 3 21  ? 171.288 146.988 129.850 1.00 77.64  ? 21  MET L CA  1 
ATOM   5999 C  C   . MET C 3 21  ? 171.985 147.025 131.207 1.00 77.64  ? 21  MET L C   1 
ATOM   6000 O  O   . MET C 3 21  ? 171.475 146.523 132.211 1.00 77.64  ? 21  MET L O   1 
ATOM   6001 C  CB  . MET C 3 21  ? 171.028 148.399 129.329 1.00 77.64  ? 21  MET L CB  1 
ATOM   6002 C  CG  . MET C 3 21  ? 170.558 148.455 127.888 1.00 77.64  ? 21  MET L CG  1 
ATOM   6003 S  SD  . MET C 3 21  ? 169.565 149.915 127.540 1.00 77.64  ? 21  MET L SD  1 
ATOM   6004 C  CE  . MET C 3 21  ? 168.177 149.172 126.690 1.00 77.64  ? 21  MET L CE  1 
ATOM   6005 N  N   . THR C 3 22  ? 173.170 147.630 131.244 1.00 76.19  ? 22  THR L N   1 
ATOM   6006 C  CA  . THR C 3 22  ? 173.901 147.763 132.495 1.00 76.19  ? 22  THR L CA  1 
ATOM   6007 C  C   . THR C 3 22  ? 174.731 149.037 132.462 1.00 76.19  ? 22  THR L C   1 
ATOM   6008 O  O   . THR C 3 22  ? 174.979 149.616 131.401 1.00 76.19  ? 22  THR L O   1 
ATOM   6009 C  CB  . THR C 3 22  ? 174.794 146.545 132.769 1.00 76.19  ? 22  THR L CB  1 
ATOM   6010 O  OG1 . THR C 3 22  ? 175.249 146.582 134.127 1.00 76.19  ? 22  THR L OG1 1 
ATOM   6011 C  CG2 . THR C 3 22  ? 175.997 146.537 131.845 1.00 76.19  ? 22  THR L CG2 1 
ATOM   6012 N  N   . CYS C 3 23  ? 175.143 149.480 133.653 1.00 77.77  ? 23  CYS L N   1 
ATOM   6013 C  CA  . CYS C 3 23  ? 175.982 150.672 133.822 1.00 77.77  ? 23  CYS L CA  1 
ATOM   6014 C  C   . CYS C 3 23  ? 176.905 150.404 135.009 1.00 77.77  ? 23  CYS L C   1 
ATOM   6015 O  O   . CYS C 3 23  ? 176.485 150.477 136.167 1.00 77.77  ? 23  CYS L O   1 
ATOM   6016 C  CB  . CYS C 3 23  ? 175.141 151.926 134.028 1.00 77.77  ? 23  CYS L CB  1 
ATOM   6017 S  SG  . CYS C 3 23  ? 176.076 153.417 134.448 1.00 77.77  ? 23  CYS L SG  1 
ATOM   6018 N  N   . ARG C 3 24  ? 178.162 150.087 134.713 1.00 82.53  ? 24  ARG L N   1 
ATOM   6019 C  CA  . ARG C 3 24  ? 179.131 149.766 135.750 1.00 82.53  ? 24  ARG L CA  1 
ATOM   6020 C  C   . ARG C 3 24  ? 179.859 151.026 136.202 1.00 82.53  ? 24  ARG L C   1 
ATOM   6021 O  O   . ARG C 3 24  ? 180.487 151.716 135.393 1.00 82.53  ? 24  ARG L O   1 
ATOM   6022 C  CB  . ARG C 3 24  ? 180.131 148.731 135.238 1.00 82.53  ? 24  ARG L CB  1 
ATOM   6023 C  CG  . ARG C 3 24  ? 179.578 147.318 135.170 1.00 82.53  ? 24  ARG L CG  1 
ATOM   6024 C  CD  . ARG C 3 24  ? 179.360 146.754 136.561 1.00 82.53  ? 24  ARG L CD  1 
ATOM   6025 N  NE  . ARG C 3 24  ? 180.625 146.518 137.246 1.00 82.53  ? 24  ARG L NE  1 
ATOM   6026 C  CZ  . ARG C 3 24  ? 180.839 146.771 138.529 1.00 82.53  ? 24  ARG L CZ  1 
ATOM   6027 N  NH1 . ARG C 3 24  ? 179.888 147.264 139.304 1.00 82.53  ? 24  ARG L NH1 1 
ATOM   6028 N  NH2 . ARG C 3 24  ? 182.039 146.526 139.047 1.00 82.53  ? 24  ARG L NH2 1 
ATOM   6029 N  N   . ALA C 3 25  ? 179.781 151.319 137.496 1.00 85.59  ? 25  ALA L N   1 
ATOM   6030 C  CA  . ALA C 3 25  ? 180.401 152.501 138.072 1.00 85.59  ? 25  ALA L CA  1 
ATOM   6031 C  C   . ALA C 3 25  ? 181.804 152.182 138.569 1.00 85.59  ? 25  ALA L C   1 
ATOM   6032 O  O   . ALA C 3 25  ? 182.068 151.091 139.081 1.00 85.59  ? 25  ALA L O   1 
ATOM   6033 C  CB  . ALA C 3 25  ? 179.559 153.052 139.223 1.00 85.59  ? 25  ALA L CB  1 
ATOM   6034 N  N   . SER C 3 26  ? 182.704 153.153 138.413 1.00 84.58  ? 26  SER L N   1 
ATOM   6035 C  CA  . SER C 3 26  ? 184.068 152.991 138.906 1.00 84.58  ? 26  SER L CA  1 
ATOM   6036 C  C   . SER C 3 26  ? 184.102 153.004 140.429 1.00 84.58  ? 26  SER L C   1 
ATOM   6037 O  O   . SER C 3 26  ? 184.737 152.150 141.058 1.00 84.58  ? 26  SER L O   1 
ATOM   6038 C  CB  . SER C 3 26  ? 184.967 154.088 138.334 1.00 84.58  ? 26  SER L CB  1 
ATOM   6039 O  OG  . SER C 3 26  ? 184.867 155.277 139.099 1.00 84.58  ? 26  SER L OG  1 
ATOM   6040 N  N   . SER C 3 27  ? 183.426 153.973 141.039 1.00 85.21  ? 27  SER L N   1 
ATOM   6041 C  CA  . SER C 3 27  ? 183.362 154.093 142.485 1.00 85.21  ? 27  SER L CA  1 
ATOM   6042 C  C   . SER C 3 27  ? 181.951 153.782 142.979 1.00 85.21  ? 27  SER L C   1 
ATOM   6043 O  O   . SER C 3 27  ? 181.004 153.649 142.200 1.00 85.21  ? 27  SER L O   1 
ATOM   6044 C  CB  . SER C 3 27  ? 183.806 155.490 142.920 1.00 85.21  ? 27  SER L CB  1 
ATOM   6045 O  OG  . SER C 3 27  ? 185.093 155.789 142.410 1.00 85.21  ? 27  SER L OG  1 
ATOM   6046 N  N   . SER C 3 28  ? 181.817 153.659 144.297 1.00 85.30  ? 28  SER L N   1 
ATOM   6047 C  CA  . SER C 3 28  ? 180.518 153.396 144.898 1.00 85.30  ? 28  SER L CA  1 
ATOM   6048 C  C   . SER C 3 28  ? 179.621 154.621 144.791 1.00 85.30  ? 28  SER L C   1 
ATOM   6049 O  O   . SER C 3 28  ? 180.052 155.752 145.029 1.00 85.30  ? 28  SER L O   1 
ATOM   6050 C  CB  . SER C 3 28  ? 180.680 152.992 146.363 1.00 85.30  ? 28  SER L CB  1 
ATOM   6051 O  OG  . SER C 3 28  ? 179.439 153.042 147.045 1.00 85.30  ? 28  SER L OG  1 
ATOM   6052 N  N   . VAL C 3 29  ? 178.363 154.387 144.433 1.00 78.19  ? 29  VAL L N   1 
ATOM   6053 C  CA  . VAL C 3 29  ? 177.383 155.449 144.266 1.00 78.19  ? 29  VAL L CA  1 
ATOM   6054 C  C   . VAL C 3 29  ? 176.132 155.060 145.042 1.00 78.19  ? 29  VAL L C   1 
ATOM   6055 O  O   . VAL C 3 29  ? 175.875 153.877 145.288 1.00 78.19  ? 29  VAL L O   1 
ATOM   6056 C  CB  . VAL C 3 29  ? 177.081 155.704 142.765 1.00 78.19  ? 29  VAL L CB  1 
ATOM   6057 C  CG1 . VAL C 3 29  ? 176.246 154.583 142.168 1.00 78.19  ? 29  VAL L CG1 1 
ATOM   6058 C  CG2 . VAL C 3 29  ? 176.428 157.061 142.544 1.00 78.19  ? 29  VAL L CG2 1 
ATOM   6059 N  N   . GLY C 3 30  ? 175.375 156.067 145.471 1.00 75.29  ? 30  GLY L N   1 
ATOM   6060 C  CA  . GLY C 3 30  ? 174.163 155.805 146.218 1.00 75.29  ? 30  GLY L CA  1 
ATOM   6061 C  C   . GLY C 3 30  ? 173.090 155.168 145.356 1.00 75.29  ? 30  GLY L C   1 
ATOM   6062 O  O   . GLY C 3 30  ? 173.049 155.335 144.138 1.00 75.29  ? 30  GLY L O   1 
ATOM   6063 N  N   . SER C 3 31  ? 172.207 154.415 146.011 1.00 76.51  ? 31  SER L N   1 
ATOM   6064 C  CA  . SER C 3 31  ? 171.130 153.736 145.304 1.00 76.51  ? 31  SER L CA  1 
ATOM   6065 C  C   . SER C 3 31  ? 170.017 154.682 144.880 1.00 76.51  ? 31  SER L C   1 
ATOM   6066 O  O   . SER C 3 31  ? 169.173 154.296 144.066 1.00 76.51  ? 31  SER L O   1 
ATOM   6067 C  CB  . SER C 3 31  ? 170.551 152.618 146.174 1.00 76.51  ? 31  SER L CB  1 
ATOM   6068 O  OG  . SER C 3 31  ? 171.558 151.701 146.566 1.00 76.51  ? 31  SER L OG  1 
ATOM   6069 N  N   . SER C 3 32  ? 169.991 155.903 145.412 1.00 73.54  ? 32  SER L N   1 
ATOM   6070 C  CA  . SER C 3 32  ? 168.966 156.880 145.070 1.00 73.54  ? 32  SER L CA  1 
ATOM   6071 C  C   . SER C 3 32  ? 169.525 158.073 144.305 1.00 73.54  ? 32  SER L C   1 
ATOM   6072 O  O   . SER C 3 32  ? 168.844 159.097 144.191 1.00 73.54  ? 32  SER L O   1 
ATOM   6073 C  CB  . SER C 3 32  ? 168.249 157.356 146.334 1.00 73.54  ? 32  SER L CB  1 
ATOM   6074 O  OG  . SER C 3 32  ? 167.111 158.133 146.010 1.00 73.54  ? 32  SER L OG  1 
ATOM   6075 N  N   . TYR C 3 33  ? 170.744 157.967 143.777 1.00 72.54  ? 33  TYR L N   1 
ATOM   6076 C  CA  . TYR C 3 33  ? 171.369 159.058 143.046 1.00 72.54  ? 33  TYR L CA  1 
ATOM   6077 C  C   . TYR C 3 33  ? 171.611 158.752 141.576 1.00 72.54  ? 33  TYR L C   1 
ATOM   6078 O  O   . TYR C 3 33  ? 171.822 159.688 140.797 1.00 72.54  ? 33  TYR L O   1 
ATOM   6079 C  CB  . TYR C 3 33  ? 172.704 159.440 143.700 1.00 72.54  ? 33  TYR L CB  1 
ATOM   6080 C  CG  . TYR C 3 33  ? 172.563 160.357 144.892 1.00 72.54  ? 33  TYR L CG  1 
ATOM   6081 C  CD1 . TYR C 3 33  ? 172.104 159.878 146.111 1.00 72.54  ? 33  TYR L CD1 1 
ATOM   6082 C  CD2 . TYR C 3 33  ? 172.896 161.700 144.799 1.00 72.54  ? 33  TYR L CD2 1 
ATOM   6083 C  CE1 . TYR C 3 33  ? 171.975 160.713 147.202 1.00 72.54  ? 33  TYR L CE1 1 
ATOM   6084 C  CE2 . TYR C 3 33  ? 172.771 162.543 145.885 1.00 72.54  ? 33  TYR L CE2 1 
ATOM   6085 C  CZ  . TYR C 3 33  ? 172.311 162.044 147.083 1.00 72.54  ? 33  TYR L CZ  1 
ATOM   6086 O  OH  . TYR C 3 33  ? 172.186 162.881 148.166 1.00 72.54  ? 33  TYR L OH  1 
ATOM   6087 N  N   . LEU C 3 34  ? 171.586 157.486 141.174 1.00 68.59  ? 34  LEU L N   1 
ATOM   6088 C  CA  . LEU C 3 34  ? 171.859 157.111 139.794 1.00 68.59  ? 34  LEU L CA  1 
ATOM   6089 C  C   . LEU C 3 34  ? 170.578 157.190 138.974 1.00 68.59  ? 34  LEU L C   1 
ATOM   6090 O  O   . LEU C 3 34  ? 169.540 156.659 139.379 1.00 68.59  ? 34  LEU L O   1 
ATOM   6091 C  CB  . LEU C 3 34  ? 172.460 155.707 139.728 1.00 68.59  ? 34  LEU L CB  1 
ATOM   6092 C  CG  . LEU C 3 34  ? 173.053 155.253 138.394 1.00 68.59  ? 34  LEU L CG  1 
ATOM   6093 C  CD1 . LEU C 3 34  ? 174.350 154.506 138.630 1.00 68.59  ? 34  LEU L CD1 1 
ATOM   6094 C  CD2 . LEU C 3 34  ? 172.078 154.369 137.636 1.00 68.59  ? 34  LEU L CD2 1 
ATOM   6095 N  N   . HIS C 3 35  ? 170.658 157.851 137.823 1.00 63.89  ? 35  HIS L N   1 
ATOM   6096 C  CA  . HIS C 3 35  ? 169.509 158.098 136.966 1.00 63.89  ? 35  HIS L CA  1 
ATOM   6097 C  C   . HIS C 3 35  ? 169.767 157.545 135.570 1.00 63.89  ? 35  HIS L C   1 
ATOM   6098 O  O   . HIS C 3 35  ? 170.906 157.285 135.179 1.00 63.89  ? 35  HIS L O   1 
ATOM   6099 C  CB  . HIS C 3 35  ? 169.196 159.596 136.886 1.00 63.89  ? 35  HIS L CB  1 
ATOM   6100 C  CG  . HIS C 3 35  ? 169.192 160.286 138.213 1.00 63.89  ? 35  HIS L CG  1 
ATOM   6101 N  ND1 . HIS C 3 35  ? 168.675 159.709 139.352 1.00 63.89  ? 35  HIS L ND1 1 
ATOM   6102 C  CD2 . HIS C 3 35  ? 169.647 161.506 138.584 1.00 63.89  ? 35  HIS L CD2 1 
ATOM   6103 C  CE1 . HIS C 3 35  ? 168.809 160.544 140.366 1.00 63.89  ? 35  HIS L CE1 1 
ATOM   6104 N  NE2 . HIS C 3 35  ? 169.396 161.642 139.927 1.00 63.89  ? 35  HIS L NE2 1 
ATOM   6105 N  N   . TRP C 3 36  ? 168.684 157.373 134.812 1.00 65.32  ? 36  TRP L N   1 
ATOM   6106 C  CA  . TRP C 3 36  ? 168.756 156.846 133.457 1.00 65.32  ? 36  TRP L CA  1 
ATOM   6107 C  C   . TRP C 3 36  ? 168.001 157.763 132.508 1.00 65.32  ? 36  TRP L C   1 
ATOM   6108 O  O   . TRP C 3 36  ? 166.886 158.198 132.809 1.00 65.32  ? 36  TRP L O   1 
ATOM   6109 C  CB  . TRP C 3 36  ? 168.177 155.430 133.373 1.00 65.32  ? 36  TRP L CB  1 
ATOM   6110 C  CG  . TRP C 3 36  ? 169.108 154.368 133.852 1.00 65.32  ? 36  TRP L CG  1 
ATOM   6111 C  CD1 . TRP C 3 36  ? 169.256 153.926 135.131 1.00 65.32  ? 36  TRP L CD1 1 
ATOM   6112 C  CD2 . TRP C 3 36  ? 170.015 153.602 133.054 1.00 65.32  ? 36  TRP L CD2 1 
ATOM   6113 N  NE1 . TRP C 3 36  ? 170.204 152.935 135.181 1.00 65.32  ? 36  TRP L NE1 1 
ATOM   6114 C  CE2 . TRP C 3 36  ? 170.685 152.718 133.917 1.00 65.32  ? 36  TRP L CE2 1 
ATOM   6115 C  CE3 . TRP C 3 36  ? 170.326 153.581 131.693 1.00 65.32  ? 36  TRP L CE3 1 
ATOM   6116 C  CZ2 . TRP C 3 36  ? 171.646 151.822 133.466 1.00 65.32  ? 36  TRP L CZ2 1 
ATOM   6117 C  CZ3 . TRP C 3 36  ? 171.281 152.691 131.246 1.00 65.32  ? 36  TRP L CZ3 1 
ATOM   6118 C  CH2 . TRP C 3 36  ? 171.931 151.825 132.130 1.00 65.32  ? 36  TRP L CH2 1 
ATOM   6119 N  N   . TYR C 3 37  ? 168.604 158.029 131.353 1.00 56.10  ? 37  TYR L N   1 
ATOM   6120 C  CA  . TYR C 3 37  ? 168.065 158.946 130.361 1.00 56.10  ? 37  TYR L CA  1 
ATOM   6121 C  C   . TYR C 3 37  ? 167.806 158.206 129.056 1.00 56.10  ? 37  TYR L C   1 
ATOM   6122 O  O   . TYR C 3 37  ? 168.266 157.082 128.849 1.00 56.10  ? 37  TYR L O   1 
ATOM   6123 C  CB  . TYR C 3 37  ? 169.025 160.118 130.128 1.00 56.10  ? 37  TYR L CB  1 
ATOM   6124 C  CG  . TYR C 3 37  ? 169.146 161.039 131.316 1.00 56.10  ? 37  TYR L CG  1 
ATOM   6125 C  CD1 . TYR C 3 37  ? 168.054 161.298 132.126 1.00 56.10  ? 37  TYR L CD1 1 
ATOM   6126 C  CD2 . TYR C 3 37  ? 170.355 161.628 131.642 1.00 56.10  ? 37  TYR L CD2 1 
ATOM   6127 C  CE1 . TYR C 3 37  ? 168.159 162.131 133.215 1.00 56.10  ? 37  TYR L CE1 1 
ATOM   6128 C  CE2 . TYR C 3 37  ? 170.468 162.460 132.732 1.00 56.10  ? 37  TYR L CE2 1 
ATOM   6129 C  CZ  . TYR C 3 37  ? 169.367 162.708 133.514 1.00 56.10  ? 37  TYR L CZ  1 
ATOM   6130 O  OH  . TYR C 3 37  ? 169.473 163.538 134.603 1.00 56.10  ? 37  TYR L OH  1 
ATOM   6131 N  N   . GLN C 3 38  ? 167.050 158.852 128.172 1.00 60.71  ? 38  GLN L N   1 
ATOM   6132 C  CA  . GLN C 3 38  ? 166.760 158.291 126.856 1.00 60.71  ? 38  GLN L CA  1 
ATOM   6133 C  C   . GLN C 3 38  ? 166.801 159.411 125.834 1.00 60.71  ? 38  GLN L C   1 
ATOM   6134 O  O   . GLN C 3 38  ? 166.031 160.368 125.939 1.00 60.71  ? 38  GLN L O   1 
ATOM   6135 C  CB  . GLN C 3 38  ? 165.397 157.602 126.828 1.00 60.71  ? 38  GLN L CB  1 
ATOM   6136 C  CG  . GLN C 3 38  ? 164.968 157.190 125.431 1.00 60.71  ? 38  GLN L CG  1 
ATOM   6137 C  CD  . GLN C 3 38  ? 163.466 157.092 125.283 1.00 60.71  ? 38  GLN L CD  1 
ATOM   6138 O  OE1 . GLN C 3 38  ? 162.771 158.104 125.216 1.00 60.71  ? 38  GLN L OE1 1 
ATOM   6139 N  NE2 . GLN C 3 38  ? 162.957 155.869 125.225 1.00 60.71  ? 38  GLN L NE2 1 
ATOM   6140 N  N   . GLN C 3 39  ? 167.684 159.289 124.847 1.00 59.56  ? 39  GLN L N   1 
ATOM   6141 C  CA  . GLN C 3 39  ? 167.845 160.304 123.815 1.00 59.56  ? 39  GLN L CA  1 
ATOM   6142 C  C   . GLN C 3 39  ? 167.496 159.704 122.463 1.00 59.56  ? 39  GLN L C   1 
ATOM   6143 O  O   . GLN C 3 39  ? 168.180 158.788 121.995 1.00 59.56  ? 39  GLN L O   1 
ATOM   6144 C  CB  . GLN C 3 39  ? 169.272 160.851 123.796 1.00 59.56  ? 39  GLN L CB  1 
ATOM   6145 C  CG  . GLN C 3 39  ? 169.525 161.811 122.654 1.00 59.56  ? 39  GLN L CG  1 
ATOM   6146 C  CD  . GLN C 3 39  ? 170.911 162.412 122.685 1.00 59.56  ? 39  GLN L CD  1 
ATOM   6147 O  OE1 . GLN C 3 39  ? 171.881 161.750 123.050 1.00 59.56  ? 39  GLN L OE1 1 
ATOM   6148 N  NE2 . GLN C 3 39  ? 171.011 163.679 122.306 1.00 59.56  ? 39  GLN L NE2 1 
ATOM   6149 N  N   . LYS C 3 40  ? 166.447 160.226 121.836 1.00 66.50  ? 40  LYS L N   1 
ATOM   6150 C  CA  . LYS C 3 40  ? 166.094 159.792 120.495 1.00 66.50  ? 40  LYS L CA  1 
ATOM   6151 C  C   . LYS C 3 40  ? 167.111 160.313 119.484 1.00 66.50  ? 40  LYS L C   1 
ATOM   6152 O  O   . LYS C 3 40  ? 167.893 161.226 119.760 1.00 66.50  ? 40  LYS L O   1 
ATOM   6153 C  CB  . LYS C 3 40  ? 164.692 160.272 120.123 1.00 66.50  ? 40  LYS L CB  1 
ATOM   6154 C  CG  . LYS C 3 40  ? 163.576 159.590 120.894 1.00 66.50  ? 40  LYS L CG  1 
ATOM   6155 C  CD  . LYS C 3 40  ? 163.101 158.333 120.182 1.00 66.50  ? 40  LYS L CD  1 
ATOM   6156 C  CE  . LYS C 3 40  ? 161.812 157.804 120.792 1.00 66.50  ? 40  LYS L CE  1 
ATOM   6157 N  NZ  . LYS C 3 40  ? 161.918 157.634 122.267 1.00 66.50  ? 40  LYS L NZ  1 
ATOM   6158 N  N   . SER C 3 41  ? 167.099 159.710 118.299 1.00 71.75  ? 41  SER L N   1 
ATOM   6159 C  CA  . SER C 3 41  ? 168.033 160.081 117.239 1.00 71.75  ? 41  SER L CA  1 
ATOM   6160 C  C   . SER C 3 41  ? 167.627 161.433 116.669 1.00 71.75  ? 41  SER L C   1 
ATOM   6161 O  O   . SER C 3 41  ? 166.705 161.529 115.857 1.00 71.75  ? 41  SER L O   1 
ATOM   6162 C  CB  . SER C 3 41  ? 168.059 159.013 116.153 1.00 71.75  ? 41  SER L CB  1 
ATOM   6163 O  OG  . SER C 3 41  ? 168.831 159.439 115.043 1.00 71.75  ? 41  SER L OG  1 
ATOM   6164 N  N   . GLY C 3 42  ? 168.318 162.486 117.095 1.00 68.24  ? 42  GLY L N   1 
ATOM   6165 C  CA  . GLY C 3 42  ? 168.029 163.822 116.614 1.00 68.24  ? 42  GLY L CA  1 
ATOM   6166 C  C   . GLY C 3 42  ? 167.076 164.586 117.507 1.00 68.24  ? 42  GLY L C   1 
ATOM   6167 O  O   . GLY C 3 42  ? 166.247 165.361 117.022 1.00 68.24  ? 42  GLY L O   1 
ATOM   6168 N  N   . ALA C 3 43  ? 167.183 164.376 118.817 1.00 61.65  ? 43  ALA L N   1 
ATOM   6169 C  CA  . ALA C 3 43  ? 166.318 165.051 119.772 1.00 61.65  ? 43  ALA L CA  1 
ATOM   6170 C  C   . ALA C 3 43  ? 167.027 165.132 121.114 1.00 61.65  ? 43  ALA L C   1 
ATOM   6171 O  O   . ALA C 3 43  ? 168.027 164.452 121.353 1.00 61.65  ? 43  ALA L O   1 
ATOM   6172 C  CB  . ALA C 3 43  ? 164.970 164.337 119.920 1.00 61.65  ? 43  ALA L CB  1 
ATOM   6173 N  N   . SER C 3 44  ? 166.498 165.986 121.984 1.00 50.37  ? 44  SER L N   1 
ATOM   6174 C  CA  . SER C 3 44  ? 167.068 166.151 123.309 1.00 50.37  ? 44  SER L CA  1 
ATOM   6175 C  C   . SER C 3 44  ? 166.754 164.938 124.182 1.00 50.37  ? 44  SER L C   1 
ATOM   6176 O  O   . SER C 3 44  ? 165.686 164.335 124.056 1.00 50.37  ? 44  SER L O   1 
ATOM   6177 C  CB  . SER C 3 44  ? 166.518 167.408 123.970 1.00 50.37  ? 44  SER L CB  1 
ATOM   6178 O  OG  . SER C 3 44  ? 165.149 167.245 124.294 1.00 50.37  ? 44  SER L OG  1 
ATOM   6179 N  N   . PRO C 3 45  ? 167.673 164.555 125.066 1.00 45.35  ? 45  PRO L N   1 
ATOM   6180 C  CA  . PRO C 3 45  ? 167.377 163.474 126.011 1.00 45.35  ? 45  PRO L CA  1 
ATOM   6181 C  C   . PRO C 3 45  ? 166.298 163.881 127.000 1.00 45.35  ? 45  PRO L C   1 
ATOM   6182 O  O   . PRO C 3 45  ? 166.141 165.055 127.338 1.00 45.35  ? 45  PRO L O   1 
ATOM   6183 C  CB  . PRO C 3 45  ? 168.716 163.239 126.720 1.00 45.35  ? 45  PRO L CB  1 
ATOM   6184 C  CG  . PRO C 3 45  ? 169.741 163.878 125.853 1.00 45.35  ? 45  PRO L CG  1 
ATOM   6185 C  CD  . PRO C 3 45  ? 169.062 165.021 125.181 1.00 45.35  ? 45  PRO L CD  1 
ATOM   6186 N  N   . LYS C 3 46  ? 165.542 162.888 127.454 1.00 51.90  ? 46  LYS L N   1 
ATOM   6187 C  CA  . LYS C 3 46  ? 164.511 163.080 128.461 1.00 51.90  ? 46  LYS L CA  1 
ATOM   6188 C  C   . LYS C 3 46  ? 164.799 162.190 129.660 1.00 51.90  ? 46  LYS L C   1 
ATOM   6189 O  O   . LYS C 3 46  ? 165.436 161.140 129.534 1.00 51.90  ? 46  LYS L O   1 
ATOM   6190 C  CB  . LYS C 3 46  ? 163.114 162.765 127.910 1.00 51.90  ? 46  LYS L CB  1 
ATOM   6191 C  CG  . LYS C 3 46  ? 162.896 163.186 126.467 1.00 51.90  ? 46  LYS L CG  1 
ATOM   6192 C  CD  . LYS C 3 46  ? 162.809 164.701 126.337 1.00 51.90  ? 46  LYS L CD  1 
ATOM   6193 C  CE  . LYS C 3 46  ? 161.756 165.291 127.267 1.00 51.90  ? 46  LYS L CE  1 
ATOM   6194 N  NZ  . LYS C 3 46  ? 161.444 166.707 126.928 1.00 51.90  ? 46  LYS L NZ  1 
ATOM   6195 N  N   . LEU C 3 47  ? 164.336 162.627 130.828 1.00 55.11  ? 47  LEU L N   1 
ATOM   6196 C  CA  . LEU C 3 47  ? 164.459 161.813 132.027 1.00 55.11  ? 47  LEU L CA  1 
ATOM   6197 C  C   . LEU C 3 47  ? 163.576 160.581 131.897 1.00 55.11  ? 47  LEU L C   1 
ATOM   6198 O  O   . LEU C 3 47  ? 162.388 160.688 131.580 1.00 55.11  ? 47  LEU L O   1 
ATOM   6199 C  CB  . LEU C 3 47  ? 164.070 162.621 133.262 1.00 55.11  ? 47  LEU L CB  1 
ATOM   6200 C  CG  . LEU C 3 47  ? 163.894 161.847 134.568 1.00 55.11  ? 47  LEU L CG  1 
ATOM   6201 C  CD1 . LEU C 3 47  ? 165.234 161.500 135.175 1.00 55.11  ? 47  LEU L CD1 1 
ATOM   6202 C  CD2 . LEU C 3 47  ? 163.059 162.646 135.550 1.00 55.11  ? 47  LEU L CD2 1 
ATOM   6203 N  N   . TRP C 3 48  ? 164.162 159.408 132.125 1.00 62.67  ? 48  TRP L N   1 
ATOM   6204 C  CA  . TRP C 3 48  ? 163.451 158.146 131.982 1.00 62.67  ? 48  TRP L CA  1 
ATOM   6205 C  C   . TRP C 3 48  ? 163.306 157.421 133.312 1.00 62.67  ? 48  TRP L C   1 
ATOM   6206 O  O   . TRP C 3 48  ? 162.190 157.086 133.720 1.00 62.67  ? 48  TRP L O   1 
ATOM   6207 C  CB  . TRP C 3 48  ? 164.174 157.257 130.962 1.00 62.67  ? 48  TRP L CB  1 
ATOM   6208 C  CG  . TRP C 3 48  ? 163.256 156.459 130.092 1.00 62.67  ? 48  TRP L CG  1 
ATOM   6209 C  CD1 . TRP C 3 48  ? 163.179 155.102 130.020 1.00 62.67  ? 48  TRP L CD1 1 
ATOM   6210 C  CD2 . TRP C 3 48  ? 162.291 156.966 129.160 1.00 62.67  ? 48  TRP L CD2 1 
ATOM   6211 N  NE1 . TRP C 3 48  ? 162.225 154.730 129.107 1.00 62.67  ? 48  TRP L NE1 1 
ATOM   6212 C  CE2 . TRP C 3 48  ? 161.665 155.856 128.564 1.00 62.67  ? 48  TRP L CE2 1 
ATOM   6213 C  CE3 . TRP C 3 48  ? 161.896 158.250 128.772 1.00 62.67  ? 48  TRP L CE3 1 
ATOM   6214 C  CZ2 . TRP C 3 48  ? 160.665 155.989 127.605 1.00 62.67  ? 48  TRP L CZ2 1 
ATOM   6215 C  CZ3 . TRP C 3 48  ? 160.902 158.379 127.821 1.00 62.67  ? 48  TRP L CZ3 1 
ATOM   6216 C  CH2 . TRP C 3 48  ? 160.299 157.256 127.247 1.00 62.67  ? 48  TRP L CH2 1 
ATOM   6217 N  N   . ILE C 3 49  ? 164.413 157.169 134.002 1.00 64.39  ? 49  ILE L N   1 
ATOM   6218 C  CA  . ILE C 3 49  ? 164.410 156.492 135.291 1.00 64.39  ? 49  ILE L CA  1 
ATOM   6219 C  C   . ILE C 3 49  ? 165.260 157.310 136.249 1.00 64.39  ? 49  ILE L C   1 
ATOM   6220 O  O   . ILE C 3 49  ? 166.418 157.616 135.947 1.00 64.39  ? 49  ILE L O   1 
ATOM   6221 C  CB  . ILE C 3 49  ? 164.943 155.051 135.175 1.00 64.39  ? 49  ILE L CB  1 
ATOM   6222 C  CG1 . ILE C 3 49  ? 163.913 154.152 134.492 1.00 64.39  ? 49  ILE L CG1 1 
ATOM   6223 C  CG2 . ILE C 3 49  ? 165.291 154.494 136.534 1.00 64.39  ? 49  ILE L CG2 1 
ATOM   6224 C  CD1 . ILE C 3 49  ? 164.360 152.716 134.346 1.00 64.39  ? 49  ILE L CD1 1 
ATOM   6225 N  N   . TYR C 3 50  ? 164.687 157.675 137.393 1.00 67.36  ? 50  TYR L N   1 
ATOM   6226 C  CA  . TYR C 3 50  ? 165.398 158.424 138.418 1.00 67.36  ? 50  TYR L CA  1 
ATOM   6227 C  C   . TYR C 3 50  ? 165.459 157.606 139.699 1.00 67.36  ? 50  TYR L C   1 
ATOM   6228 O  O   . TYR C 3 50  ? 164.483 156.946 140.069 1.00 67.36  ? 50  TYR L O   1 
ATOM   6229 C  CB  . TYR C 3 50  ? 164.740 159.784 138.681 1.00 67.36  ? 50  TYR L CB  1 
ATOM   6230 C  CG  . TYR C 3 50  ? 163.299 159.736 139.139 1.00 67.36  ? 50  TYR L CG  1 
ATOM   6231 C  CD1 . TYR C 3 50  ? 162.260 159.666 138.221 1.00 67.36  ? 50  TYR L CD1 1 
ATOM   6232 C  CD2 . TYR C 3 50  ? 162.976 159.795 140.488 1.00 67.36  ? 50  TYR L CD2 1 
ATOM   6233 C  CE1 . TYR C 3 50  ? 160.943 159.636 138.633 1.00 67.36  ? 50  TYR L CE1 1 
ATOM   6234 C  CE2 . TYR C 3 50  ? 161.662 159.764 140.910 1.00 67.36  ? 50  TYR L CE2 1 
ATOM   6235 C  CZ  . TYR C 3 50  ? 160.651 159.686 139.978 1.00 67.36  ? 50  TYR L CZ  1 
ATOM   6236 O  OH  . TYR C 3 50  ? 159.340 159.656 140.394 1.00 67.36  ? 50  TYR L OH  1 
ATOM   6237 N  N   . SER C 3 51  ? 166.624 157.653 140.356 1.00 67.71  ? 51  SER L N   1 
ATOM   6238 C  CA  . SER C 3 51  ? 166.940 156.855 141.546 1.00 67.71  ? 51  SER L CA  1 
ATOM   6239 C  C   . SER C 3 51  ? 166.798 155.358 141.283 1.00 67.71  ? 51  SER L C   1 
ATOM   6240 O  O   . SER C 3 51  ? 166.368 154.608 142.161 1.00 67.71  ? 51  SER L O   1 
ATOM   6241 C  CB  . SER C 3 51  ? 166.093 157.273 142.752 1.00 67.71  ? 51  SER L CB  1 
ATOM   6242 O  OG  . SER C 3 51  ? 166.506 158.533 143.250 1.00 67.71  ? 51  SER L OG  1 
ATOM   6243 N  N   . THR C 3 52  ? 167.093 154.947 140.043 1.00 70.38  ? 52  THR L N   1 
ATOM   6244 C  CA  . THR C 3 52  ? 167.224 153.582 139.516 1.00 70.38  ? 52  THR L CA  1 
ATOM   6245 C  C   . THR C 3 52  ? 166.049 152.650 139.819 1.00 70.38  ? 52  THR L C   1 
ATOM   6246 O  O   . THR C 3 52  ? 166.136 151.443 139.570 1.00 70.38  ? 52  THR L O   1 
ATOM   6247 C  CB  . THR C 3 52  ? 168.550 152.929 139.966 1.00 70.38  ? 52  THR L CB  1 
ATOM   6248 O  OG1 . THR C 3 52  ? 168.812 151.791 139.137 1.00 70.38  ? 52  THR L OG1 1 
ATOM   6249 C  CG2 . THR C 3 52  ? 168.533 152.441 141.418 1.00 70.38  ? 52  THR L CG2 1 
ATOM   6250 N  N   . SER C 3 53  ? 164.928 153.187 140.297 1.00 70.74  ? 53  SER L N   1 
ATOM   6251 C  CA  . SER C 3 53  ? 163.771 152.347 140.578 1.00 70.74  ? 53  SER L CA  1 
ATOM   6252 C  C   . SER C 3 53  ? 162.497 152.923 139.976 1.00 70.74  ? 53  SER L C   1 
ATOM   6253 O  O   . SER C 3 53  ? 161.652 152.181 139.466 1.00 70.74  ? 53  SER L O   1 
ATOM   6254 C  CB  . SER C 3 53  ? 163.603 152.164 142.087 1.00 70.74  ? 53  SER L CB  1 
ATOM   6255 O  OG  . SER C 3 53  ? 164.567 151.261 142.601 1.00 70.74  ? 53  SER L OG  1 
ATOM   6256 N  N   . ASN C 3 54  ? 162.355 154.243 140.022 1.00 72.79  ? 54  ASN L N   1 
ATOM   6257 C  CA  . ASN C 3 54  ? 161.113 154.890 139.644 1.00 72.79  ? 54  ASN L CA  1 
ATOM   6258 C  C   . ASN C 3 54  ? 161.082 155.157 138.142 1.00 72.79  ? 54  ASN L C   1 
ATOM   6259 O  O   . ASN C 3 54  ? 162.020 154.845 137.405 1.00 72.79  ? 54  ASN L O   1 
ATOM   6260 C  CB  . ASN C 3 54  ? 160.930 156.184 140.433 1.00 72.79  ? 54  ASN L CB  1 
ATOM   6261 C  CG  . ASN C 3 54  ? 160.810 155.945 141.923 1.00 72.79  ? 54  ASN L CG  1 
ATOM   6262 O  OD1 . ASN C 3 54  ? 161.676 156.348 142.700 1.00 72.79  ? 54  ASN L OD1 1 
ATOM   6263 N  ND2 . ASN C 3 54  ? 159.732 155.289 142.332 1.00 72.79  ? 54  ASN L ND2 1 
ATOM   6264 N  N   . LEU C 3 55  ? 159.979 155.739 137.681 1.00 73.62  ? 55  LEU L N   1 
ATOM   6265 C  CA  . LEU C 3 55  ? 159.816 156.131 136.291 1.00 73.62  ? 55  LEU L CA  1 
ATOM   6266 C  C   . LEU C 3 55  ? 159.318 157.566 136.234 1.00 73.62  ? 55  LEU L C   1 
ATOM   6267 O  O   . LEU C 3 55  ? 158.569 158.014 137.106 1.00 73.62  ? 55  LEU L O   1 
ATOM   6268 C  CB  . LEU C 3 55  ? 158.837 155.209 135.555 1.00 73.62  ? 55  LEU L CB  1 
ATOM   6269 C  CG  . LEU C 3 55  ? 159.170 153.717 135.551 1.00 73.62  ? 55  LEU L CG  1 
ATOM   6270 C  CD1 . LEU C 3 55  ? 157.922 152.888 135.287 1.00 73.62  ? 55  LEU L CD1 1 
ATOM   6271 C  CD2 . LEU C 3 55  ? 160.253 153.409 134.534 1.00 73.62  ? 55  LEU L CD2 1 
ATOM   6272 N  N   . ALA C 3 56  ? 159.738 158.286 135.198 1.00 71.21  ? 56  ALA L N   1 
ATOM   6273 C  CA  . ALA C 3 56  ? 159.341 159.674 135.038 1.00 71.21  ? 56  ALA L CA  1 
ATOM   6274 C  C   . ALA C 3 56  ? 157.933 159.762 134.452 1.00 71.21  ? 56  ALA L C   1 
ATOM   6275 O  O   . ALA C 3 56  ? 157.261 158.754 134.215 1.00 71.21  ? 56  ALA L O   1 
ATOM   6276 C  CB  . ALA C 3 56  ? 160.346 160.418 134.165 1.00 71.21  ? 56  ALA L CB  1 
ATOM   6277 N  N   . SER C 3 57  ? 157.480 160.990 134.217 1.00 79.76  ? 57  SER L N   1 
ATOM   6278 C  CA  . SER C 3 57  ? 156.148 161.207 133.670 1.00 79.76  ? 57  SER L CA  1 
ATOM   6279 C  C   . SER C 3 57  ? 156.111 160.820 132.197 1.00 79.76  ? 57  SER L C   1 
ATOM   6280 O  O   . SER C 3 57  ? 156.957 161.251 131.408 1.00 79.76  ? 57  SER L O   1 
ATOM   6281 C  CB  . SER C 3 57  ? 155.735 162.668 133.846 1.00 79.76  ? 57  SER L CB  1 
ATOM   6282 O  OG  . SER C 3 57  ? 154.422 162.889 133.364 1.00 79.76  ? 57  SER L OG  1 
ATOM   6283 N  N   . GLY C 3 58  ? 155.125 160.003 131.828 1.00 80.95  ? 58  GLY L N   1 
ATOM   6284 C  CA  . GLY C 3 58  ? 154.978 159.532 130.469 1.00 80.95  ? 58  GLY L CA  1 
ATOM   6285 C  C   . GLY C 3 58  ? 155.730 158.260 130.146 1.00 80.95  ? 58  GLY L C   1 
ATOM   6286 O  O   . GLY C 3 58  ? 155.537 157.706 129.056 1.00 80.95  ? 58  GLY L O   1 
ATOM   6287 N  N   . VAL C 3 59  ? 156.575 157.782 131.048 1.00 76.61  ? 59  VAL L N   1 
ATOM   6288 C  CA  . VAL C 3 59  ? 157.333 156.552 130.797 1.00 76.61  ? 59  VAL L CA  1 
ATOM   6289 C  C   . VAL C 3 59  ? 156.407 155.351 130.952 1.00 76.61  ? 59  VAL L C   1 
ATOM   6290 O  O   . VAL C 3 59  ? 155.690 155.256 131.964 1.00 76.61  ? 59  VAL L O   1 
ATOM   6291 C  CB  . VAL C 3 59  ? 158.518 156.455 131.755 1.00 76.61  ? 59  VAL L CB  1 
ATOM   6292 C  CG1 . VAL C 3 59  ? 159.387 155.262 131.400 1.00 76.61  ? 59  VAL L CG1 1 
ATOM   6293 C  CG2 . VAL C 3 59  ? 159.327 157.738 131.718 1.00 76.61  ? 59  VAL L CG2 1 
ATOM   6294 N  N   . PRO C 3 60  ? 156.365 154.434 129.987 1.00 85.15  ? 60  PRO L N   1 
ATOM   6295 C  CA  . PRO C 3 60  ? 155.569 153.214 130.164 1.00 85.15  ? 60  PRO L CA  1 
ATOM   6296 C  C   . PRO C 3 60  ? 156.141 152.324 131.257 1.00 85.15  ? 60  PRO L C   1 
ATOM   6297 O  O   . PRO C 3 60  ? 157.345 152.318 131.524 1.00 85.15  ? 60  PRO L O   1 
ATOM   6298 C  CB  . PRO C 3 60  ? 155.648 152.534 128.792 1.00 85.15  ? 60  PRO L CB  1 
ATOM   6299 C  CG  . PRO C 3 60  ? 156.872 153.091 128.162 1.00 85.15  ? 60  PRO L CG  1 
ATOM   6300 C  CD  . PRO C 3 60  ? 156.982 154.501 128.653 1.00 85.15  ? 60  PRO L CD  1 
ATOM   6301 N  N   . ALA C 3 61  ? 155.248 151.561 131.891 1.00 90.65  ? 61  ALA L N   1 
ATOM   6302 C  CA  . ALA C 3 61  ? 155.607 150.752 133.050 1.00 90.65  ? 61  ALA L CA  1 
ATOM   6303 C  C   . ALA C 3 61  ? 156.463 149.541 132.702 1.00 90.65  ? 61  ALA L C   1 
ATOM   6304 O  O   . ALA C 3 61  ? 156.977 148.890 133.618 1.00 90.65  ? 61  ALA L O   1 
ATOM   6305 C  CB  . ALA C 3 61  ? 154.341 150.293 133.776 1.00 90.65  ? 61  ALA L CB  1 
ATOM   6306 N  N   . ARG C 3 62  ? 156.626 149.219 131.417 1.00 93.24  ? 62  ARG L N   1 
ATOM   6307 C  CA  . ARG C 3 62  ? 157.456 148.085 131.028 1.00 93.24  ? 62  ARG L CA  1 
ATOM   6308 C  C   . ARG C 3 62  ? 158.940 148.338 131.265 1.00 93.24  ? 62  ARG L C   1 
ATOM   6309 O  O   . ARG C 3 62  ? 159.712 147.378 131.350 1.00 93.24  ? 62  ARG L O   1 
ATOM   6310 C  CB  . ARG C 3 62  ? 157.198 147.736 129.563 1.00 93.24  ? 62  ARG L CB  1 
ATOM   6311 C  CG  . ARG C 3 62  ? 157.316 148.913 128.623 1.00 93.24  ? 62  ARG L CG  1 
ATOM   6312 C  CD  . ARG C 3 62  ? 156.908 148.531 127.214 1.00 93.24  ? 62  ARG L CD  1 
ATOM   6313 N  NE  . ARG C 3 62  ? 156.770 149.706 126.364 1.00 93.24  ? 62  ARG L NE  1 
ATOM   6314 C  CZ  . ARG C 3 62  ? 157.769 150.261 125.695 1.00 93.24  ? 62  ARG L CZ  1 
ATOM   6315 N  NH1 . ARG C 3 62  ? 158.994 149.766 125.749 1.00 93.24  ? 62  ARG L NH1 1 
ATOM   6316 N  NH2 . ARG C 3 62  ? 157.534 151.340 124.954 1.00 93.24  ? 62  ARG L NH2 1 
ATOM   6317 N  N   . PHE C 3 63  ? 159.355 149.597 131.367 1.00 84.31  ? 63  PHE L N   1 
ATOM   6318 C  CA  . PHE C 3 63  ? 160.699 149.913 131.826 1.00 84.31  ? 63  PHE L CA  1 
ATOM   6319 C  C   . PHE C 3 63  ? 160.782 149.723 133.333 1.00 84.31  ? 63  PHE L C   1 
ATOM   6320 O  O   . PHE C 3 63  ? 159.869 150.102 134.071 1.00 84.31  ? 63  PHE L O   1 
ATOM   6321 C  CB  . PHE C 3 63  ? 161.070 151.352 131.466 1.00 84.31  ? 63  PHE L CB  1 
ATOM   6322 C  CG  . PHE C 3 63  ? 161.243 151.588 129.995 1.00 84.31  ? 63  PHE L CG  1 
ATOM   6323 C  CD1 . PHE C 3 63  ? 162.479 151.418 129.396 1.00 84.31  ? 63  PHE L CD1 1 
ATOM   6324 C  CD2 . PHE C 3 63  ? 160.171 151.986 129.213 1.00 84.31  ? 63  PHE L CD2 1 
ATOM   6325 C  CE1 . PHE C 3 63  ? 162.642 151.642 128.045 1.00 84.31  ? 63  PHE L CE1 1 
ATOM   6326 C  CE2 . PHE C 3 63  ? 160.330 152.207 127.858 1.00 84.31  ? 63  PHE L CE2 1 
ATOM   6327 C  CZ  . PHE C 3 63  ? 161.567 152.033 127.275 1.00 84.31  ? 63  PHE L CZ  1 
ATOM   6328 N  N   . SER C 3 64  ? 161.885 149.135 133.790 1.00 82.28  ? 64  SER L N   1 
ATOM   6329 C  CA  . SER C 3 64  ? 162.065 148.894 135.220 1.00 82.28  ? 64  SER L CA  1 
ATOM   6330 C  C   . SER C 3 64  ? 163.556 148.810 135.511 1.00 82.28  ? 64  SER L C   1 
ATOM   6331 O  O   . SER C 3 64  ? 164.222 147.874 135.059 1.00 82.28  ? 64  SER L O   1 
ATOM   6332 C  CB  . SER C 3 64  ? 161.346 147.620 135.649 1.00 82.28  ? 64  SER L CB  1 
ATOM   6333 O  OG  . SER C 3 64  ? 161.919 146.478 135.037 1.00 82.28  ? 64  SER L OG  1 
ATOM   6334 N  N   . GLY C 3 65  ? 164.073 149.783 136.253 1.00 77.54  ? 65  GLY L N   1 
ATOM   6335 C  CA  . GLY C 3 65  ? 165.450 149.730 136.686 1.00 77.54  ? 65  GLY L CA  1 
ATOM   6336 C  C   . GLY C 3 65  ? 165.638 148.815 137.878 1.00 77.54  ? 65  GLY L C   1 
ATOM   6337 O  O   . GLY C 3 65  ? 164.699 148.476 138.595 1.00 77.54  ? 65  GLY L O   1 
ATOM   6338 N  N   . SER C 3 66  ? 166.888 148.416 138.089 1.00 78.53  ? 66  SER L N   1 
ATOM   6339 C  CA  . SER C 3 66  ? 167.233 147.525 139.188 1.00 78.53  ? 66  SER L CA  1 
ATOM   6340 C  C   . SER C 3 66  ? 168.706 147.721 139.520 1.00 78.53  ? 66  SER L C   1 
ATOM   6341 O  O   . SER C 3 66  ? 169.389 148.565 138.935 1.00 78.53  ? 66  SER L O   1 
ATOM   6342 C  CB  . SER C 3 66  ? 166.928 146.066 138.838 1.00 78.53  ? 66  SER L CB  1 
ATOM   6343 O  OG  . SER C 3 66  ? 167.833 145.576 137.865 1.00 78.53  ? 66  SER L OG  1 
ATOM   6344 N  N   . GLY C 3 67  ? 169.190 146.928 140.467 1.00 83.71  ? 67  GLY L N   1 
ATOM   6345 C  CA  . GLY C 3 67  ? 170.573 146.991 140.885 1.00 83.71  ? 67  GLY L CA  1 
ATOM   6346 C  C   . GLY C 3 67  ? 170.806 148.022 141.976 1.00 83.71  ? 67  GLY L C   1 
ATOM   6347 O  O   . GLY C 3 67  ? 170.029 148.954 142.176 1.00 83.71  ? 67  GLY L O   1 
ATOM   6348 N  N   . SER C 3 68  ? 171.911 147.838 142.693 1.00 89.11  ? 68  SER L N   1 
ATOM   6349 C  CA  . SER C 3 68  ? 172.287 148.745 143.766 1.00 89.11  ? 68  SER L CA  1 
ATOM   6350 C  C   . SER C 3 68  ? 173.790 148.653 143.976 1.00 89.11  ? 68  SER L C   1 
ATOM   6351 O  O   . SER C 3 68  ? 174.435 147.686 143.564 1.00 89.11  ? 68  SER L O   1 
ATOM   6352 C  CB  . SER C 3 68  ? 171.536 148.425 145.063 1.00 89.11  ? 68  SER L CB  1 
ATOM   6353 O  OG  . SER C 3 68  ? 170.177 148.816 144.974 1.00 89.11  ? 68  SER L OG  1 
ATOM   6354 N  N   . GLY C 3 69  ? 174.341 149.679 144.620 1.00 82.49  ? 69  GLY L N   1 
ATOM   6355 C  CA  . GLY C 3 69  ? 175.765 149.722 144.881 1.00 82.49  ? 69  GLY L CA  1 
ATOM   6356 C  C   . GLY C 3 69  ? 176.548 150.310 143.728 1.00 82.49  ? 69  GLY L C   1 
ATOM   6357 O  O   . GLY C 3 69  ? 176.620 151.532 143.574 1.00 82.49  ? 69  GLY L O   1 
ATOM   6358 N  N   . THR C 3 70  ? 177.146 149.446 142.912 1.00 82.70  ? 70  THR L N   1 
ATOM   6359 C  CA  . THR C 3 70  ? 177.869 149.864 141.720 1.00 82.70  ? 70  THR L CA  1 
ATOM   6360 C  C   . THR C 3 70  ? 177.311 149.278 140.434 1.00 82.70  ? 70  THR L C   1 
ATOM   6361 O  O   . THR C 3 70  ? 177.435 149.910 139.383 1.00 82.70  ? 70  THR L O   1 
ATOM   6362 C  CB  . THR C 3 70  ? 179.354 149.480 141.824 1.00 82.70  ? 70  THR L CB  1 
ATOM   6363 O  OG1 . THR C 3 70  ? 179.470 148.068 142.036 1.00 82.70  ? 70  THR L OG1 1 
ATOM   6364 C  CG2 . THR C 3 70  ? 180.019 150.213 142.974 1.00 82.70  ? 70  THR L CG2 1 
ATOM   6365 N  N   . SER C 3 71  ? 176.702 148.096 140.486 1.00 83.60  ? 71  SER L N   1 
ATOM   6366 C  CA  . SER C 3 71  ? 176.118 147.463 139.309 1.00 83.60  ? 71  SER L CA  1 
ATOM   6367 C  C   . SER C 3 71  ? 174.642 147.835 139.238 1.00 83.60  ? 71  SER L C   1 
ATOM   6368 O  O   . SER C 3 71  ? 173.872 147.534 140.156 1.00 83.60  ? 71  SER L O   1 
ATOM   6369 C  CB  . SER C 3 71  ? 176.301 145.949 139.364 1.00 83.60  ? 71  SER L CB  1 
ATOM   6370 O  OG  . SER C 3 71  ? 175.683 145.321 138.254 1.00 83.60  ? 71  SER L OG  1 
ATOM   6371 N  N   . TYR C 3 72  ? 174.248 148.489 138.149 1.00 81.62  ? 72  TYR L N   1 
ATOM   6372 C  CA  . TYR C 3 72  ? 172.875 148.922 137.945 1.00 81.62  ? 72  TYR L CA  1 
ATOM   6373 C  C   . TYR C 3 72  ? 172.411 148.457 136.575 1.00 81.62  ? 72  TYR L C   1 
ATOM   6374 O  O   . TYR C 3 72  ? 173.222 148.311 135.657 1.00 81.62  ? 72  TYR L O   1 
ATOM   6375 C  CB  . TYR C 3 72  ? 172.744 150.444 138.057 1.00 81.62  ? 72  TYR L CB  1 
ATOM   6376 C  CG  . TYR C 3 72  ? 172.951 150.977 139.457 1.00 81.62  ? 72  TYR L CG  1 
ATOM   6377 C  CD1 . TYR C 3 72  ? 174.228 151.160 139.968 1.00 81.62  ? 72  TYR L CD1 1 
ATOM   6378 C  CD2 . TYR C 3 72  ? 171.869 151.297 140.267 1.00 81.62  ? 72  TYR L CD2 1 
ATOM   6379 C  CE1 . TYR C 3 72  ? 174.423 151.643 141.243 1.00 81.62  ? 72  TYR L CE1 1 
ATOM   6380 C  CE2 . TYR C 3 72  ? 172.055 151.783 141.546 1.00 81.62  ? 72  TYR L CE2 1 
ATOM   6381 C  CZ  . TYR C 3 72  ? 173.335 151.955 142.028 1.00 81.62  ? 72  TYR L CZ  1 
ATOM   6382 O  OH  . TYR C 3 72  ? 173.530 152.439 143.300 1.00 81.62  ? 72  TYR L OH  1 
ATOM   6383 N  N   . SER C 3 73  ? 171.108 148.223 136.439 1.00 76.72  ? 73  SER L N   1 
ATOM   6384 C  CA  . SER C 3 73  ? 170.559 147.669 135.211 1.00 76.72  ? 73  SER L CA  1 
ATOM   6385 C  C   . SER C 3 73  ? 169.241 148.348 134.874 1.00 76.72  ? 73  SER L C   1 
ATOM   6386 O  O   . SER C 3 73  ? 168.563 148.893 135.748 1.00 76.72  ? 73  SER L O   1 
ATOM   6387 C  CB  . SER C 3 73  ? 170.343 146.155 135.329 1.00 76.72  ? 73  SER L CB  1 
ATOM   6388 O  OG  . SER C 3 73  ? 171.573 145.479 135.524 1.00 76.72  ? 73  SER L OG  1 
ATOM   6389 N  N   . LEU C 3 74  ? 168.887 148.305 133.592 1.00 76.07  ? 74  LEU L N   1 
ATOM   6390 C  CA  . LEU C 3 74  ? 167.597 148.772 133.100 1.00 76.07  ? 74  LEU L CA  1 
ATOM   6391 C  C   . LEU C 3 74  ? 166.956 147.628 132.330 1.00 76.07  ? 74  LEU L C   1 
ATOM   6392 O  O   . LEU C 3 74  ? 167.528 147.141 131.349 1.00 76.07  ? 74  LEU L O   1 
ATOM   6393 C  CB  . LEU C 3 74  ? 167.762 150.016 132.220 1.00 76.07  ? 74  LEU L CB  1 
ATOM   6394 C  CG  . LEU C 3 74  ? 166.539 150.816 131.756 1.00 76.07  ? 74  LEU L CG  1 
ATOM   6395 C  CD1 . LEU C 3 74  ? 166.915 152.280 131.630 1.00 76.07  ? 74  LEU L CD1 1 
ATOM   6396 C  CD2 . LEU C 3 74  ? 165.993 150.317 130.426 1.00 76.07  ? 74  LEU L CD2 1 
ATOM   6397 N  N   . THR C 3 75  ? 165.771 147.207 132.765 1.00 83.00  ? 75  THR L N   1 
ATOM   6398 C  CA  . THR C 3 75  ? 165.098 146.041 132.212 1.00 83.00  ? 75  THR L CA  1 
ATOM   6399 C  C   . THR C 3 75  ? 163.832 146.474 131.489 1.00 83.00  ? 75  THR L C   1 
ATOM   6400 O  O   . THR C 3 75  ? 163.095 147.336 131.980 1.00 83.00  ? 75  THR L O   1 
ATOM   6401 C  CB  . THR C 3 75  ? 164.751 145.032 133.310 1.00 83.00  ? 75  THR L CB  1 
ATOM   6402 O  OG1 . THR C 3 75  ? 163.975 145.678 134.325 1.00 83.00  ? 75  THR L OG1 1 
ATOM   6403 C  CG2 . THR C 3 75  ? 166.016 144.473 133.938 1.00 83.00  ? 75  THR L CG2 1 
ATOM   6404 N  N   . ILE C 3 76  ? 163.584 145.875 130.326 1.00 91.78  ? 76  ILE L N   1 
ATOM   6405 C  CA  . ILE C 3 76  ? 162.403 146.153 129.520 1.00 91.78  ? 76  ILE L CA  1 
ATOM   6406 C  C   . ILE C 3 76  ? 161.685 144.833 129.276 1.00 91.78  ? 76  ILE L C   1 
ATOM   6407 O  O   . ILE C 3 76  ? 162.320 143.831 128.930 1.00 91.78  ? 76  ILE L O   1 
ATOM   6408 C  CB  . ILE C 3 76  ? 162.772 146.818 128.178 1.00 91.78  ? 76  ILE L CB  1 
ATOM   6409 C  CG1 . ILE C 3 76  ? 163.579 148.095 128.399 1.00 91.78  ? 76  ILE L CG1 1 
ATOM   6410 C  CG2 . ILE C 3 76  ? 161.516 147.165 127.396 1.00 91.78  ? 76  ILE L CG2 1 
ATOM   6411 C  CD1 . ILE C 3 76  ? 164.229 148.611 127.133 1.00 91.78  ? 76  ILE L CD1 1 
ATOM   6412 N  N   . SER C 3 77  ? 160.363 144.829 129.457 1.00 101.40 ? 77  SER L N   1 
ATOM   6413 C  CA  . SER C 3 77  ? 159.594 143.612 129.217 1.00 101.40 ? 77  SER L CA  1 
ATOM   6414 C  C   . SER C 3 77  ? 159.480 143.315 127.724 1.00 101.40 ? 77  SER L C   1 
ATOM   6415 O  O   . SER C 3 77  ? 159.935 142.269 127.252 1.00 101.40 ? 77  SER L O   1 
ATOM   6416 C  CB  . SER C 3 77  ? 158.206 143.731 129.851 1.00 101.40 ? 77  SER L CB  1 
ATOM   6417 O  OG  . SER C 3 77  ? 157.332 144.478 129.025 1.00 101.40 ? 77  SER L OG  1 
ATOM   6418 N  N   . SER C 3 78  ? 158.884 144.228 126.962 1.00 101.59 ? 78  SER L N   1 
ATOM   6419 C  CA  . SER C 3 78  ? 158.691 144.041 125.525 1.00 101.59 ? 78  SER L CA  1 
ATOM   6420 C  C   . SER C 3 78  ? 158.963 145.366 124.818 1.00 101.59 ? 78  SER L C   1 
ATOM   6421 O  O   . SER C 3 78  ? 158.255 146.352 125.041 1.00 101.59 ? 78  SER L O   1 
ATOM   6422 C  CB  . SER C 3 78  ? 157.286 143.529 125.222 1.00 101.59 ? 78  SER L CB  1 
ATOM   6423 O  OG  . SER C 3 78  ? 156.304 144.482 125.590 1.00 101.59 ? 78  SER L OG  1 
ATOM   6424 N  N   . VAL C 3 79  ? 159.986 145.385 123.969 1.00 95.62  ? 79  VAL L N   1 
ATOM   6425 C  CA  . VAL C 3 79  ? 160.310 146.575 123.192 1.00 95.62  ? 79  VAL L CA  1 
ATOM   6426 C  C   . VAL C 3 79  ? 159.386 146.662 121.985 1.00 95.62  ? 79  VAL L C   1 
ATOM   6427 O  O   . VAL C 3 79  ? 158.831 145.660 121.520 1.00 95.62  ? 79  VAL L O   1 
ATOM   6428 C  CB  . VAL C 3 79  ? 161.790 146.564 122.761 1.00 95.62  ? 79  VAL L CB  1 
ATOM   6429 C  CG1 . VAL C 3 79  ? 162.700 146.605 123.969 1.00 95.62  ? 79  VAL L CG1 1 
ATOM   6430 C  CG2 . VAL C 3 79  ? 162.088 145.342 121.917 1.00 95.62  ? 79  VAL L CG2 1 
ATOM   6431 N  N   . GLU C 3 80  ? 159.211 147.880 121.477 1.00 96.41  ? 80  GLU L N   1 
ATOM   6432 C  CA  . GLU C 3 80  ? 158.513 148.084 120.214 1.00 96.41  ? 80  GLU L CA  1 
ATOM   6433 C  C   . GLU C 3 80  ? 159.232 149.155 119.405 1.00 96.41  ? 80  GLU L C   1 
ATOM   6434 O  O   . GLU C 3 80  ? 160.352 149.544 119.745 1.00 96.41  ? 80  GLU L O   1 
ATOM   6435 C  CB  . GLU C 3 80  ? 157.048 148.466 120.444 1.00 96.41  ? 80  GLU L CB  1 
ATOM   6436 C  CG  . GLU C 3 80  ? 156.831 149.737 121.244 1.00 96.41  ? 80  GLU L CG  1 
ATOM   6437 C  CD  . GLU C 3 80  ? 156.308 149.465 122.639 1.00 96.41  ? 80  GLU L CD  1 
ATOM   6438 O  OE1 . GLU C 3 80  ? 156.372 148.299 123.083 1.00 96.41  ? 80  GLU L OE1 1 
ATOM   6439 O  OE2 . GLU C 3 80  ? 155.819 150.415 123.286 1.00 96.41  ? 80  GLU L OE2 1 
ATOM   6440 N  N   . ALA C 3 81  ? 158.604 149.637 118.333 1.00 91.40  ? 81  ALA L N   1 
ATOM   6441 C  CA  . ALA C 3 81  ? 159.238 150.643 117.490 1.00 91.40  ? 81  ALA L CA  1 
ATOM   6442 C  C   . ALA C 3 81  ? 159.275 152.025 118.131 1.00 91.40  ? 81  ALA L C   1 
ATOM   6443 O  O   . ALA C 3 81  ? 159.943 152.916 117.596 1.00 91.40  ? 81  ALA L O   1 
ATOM   6444 C  CB  . ALA C 3 81  ? 158.520 150.722 116.142 1.00 91.40  ? 81  ALA L CB  1 
ATOM   6445 N  N   . GLU C 3 82  ? 158.588 152.227 119.254 1.00 92.88  ? 82  GLU L N   1 
ATOM   6446 C  CA  . GLU C 3 82  ? 158.469 153.547 119.857 1.00 92.88  ? 82  GLU L CA  1 
ATOM   6447 C  C   . GLU C 3 82  ? 159.576 153.870 120.852 1.00 92.88  ? 82  GLU L C   1 
ATOM   6448 O  O   . GLU C 3 82  ? 159.605 154.993 121.367 1.00 92.88  ? 82  GLU L O   1 
ATOM   6449 C  CB  . GLU C 3 82  ? 157.113 153.685 120.556 1.00 92.88  ? 82  GLU L CB  1 
ATOM   6450 N  N   . ASP C 3 83  ? 160.477 152.936 121.145 1.00 86.91  ? 83  ASP L N   1 
ATOM   6451 C  CA  . ASP C 3 83  ? 161.568 153.192 122.084 1.00 86.91  ? 83  ASP L CA  1 
ATOM   6452 C  C   . ASP C 3 83  ? 162.894 152.678 121.531 1.00 86.91  ? 83  ASP L C   1 
ATOM   6453 O  O   . ASP C 3 83  ? 163.664 151.998 122.212 1.00 86.91  ? 83  ASP L O   1 
ATOM   6454 C  CB  . ASP C 3 83  ? 161.265 152.604 123.462 1.00 86.91  ? 83  ASP L CB  1 
ATOM   6455 C  CG  . ASP C 3 83  ? 160.962 151.121 123.422 1.00 86.91  ? 83  ASP L CG  1 
ATOM   6456 O  OD1 . ASP C 3 83  ? 160.893 150.544 122.322 1.00 86.91  ? 83  ASP L OD1 1 
ATOM   6457 O  OD2 . ASP C 3 83  ? 160.804 150.526 124.505 1.00 86.91  ? 83  ASP L OD2 1 
ATOM   6458 N  N   . ALA C 3 84  ? 163.174 153.004 120.273 1.00 83.20  ? 84  ALA L N   1 
ATOM   6459 C  CA  . ALA C 3 84  ? 164.482 152.746 119.675 1.00 83.20  ? 84  ALA L CA  1 
ATOM   6460 C  C   . ALA C 3 84  ? 165.299 154.028 119.790 1.00 83.20  ? 84  ALA L C   1 
ATOM   6461 O  O   . ALA C 3 84  ? 165.108 154.971 119.019 1.00 83.20  ? 84  ALA L O   1 
ATOM   6462 C  CB  . ALA C 3 84  ? 164.338 152.295 118.227 1.00 83.20  ? 84  ALA L CB  1 
ATOM   6463 N  N   . ALA C 3 85  ? 166.215 154.063 120.752 1.00 75.65  ? 85  ALA L N   1 
ATOM   6464 C  CA  . ALA C 3 85  ? 166.950 155.281 121.073 1.00 75.65  ? 85  ALA L CA  1 
ATOM   6465 C  C   . ALA C 3 85  ? 168.255 154.893 121.759 1.00 75.65  ? 85  ALA L C   1 
ATOM   6466 O  O   . ALA C 3 85  ? 168.675 153.732 121.723 1.00 75.65  ? 85  ALA L O   1 
ATOM   6467 C  CB  . ALA C 3 85  ? 166.099 156.213 121.941 1.00 75.65  ? 85  ALA L CB  1 
ATOM   6468 N  N   . THR C 3 86  ? 168.905 155.876 122.380 1.00 72.15  ? 86  THR L N   1 
ATOM   6469 C  CA  . THR C 3 86  ? 170.153 155.682 123.104 1.00 72.15  ? 86  THR L CA  1 
ATOM   6470 C  C   . THR C 3 86  ? 169.948 156.044 124.568 1.00 72.15  ? 86  THR L C   1 
ATOM   6471 O  O   . THR C 3 86  ? 169.286 157.038 124.881 1.00 72.15  ? 86  THR L O   1 
ATOM   6472 C  CB  . THR C 3 86  ? 171.276 156.535 122.509 1.00 72.15  ? 86  THR L CB  1 
ATOM   6473 O  OG1 . THR C 3 86  ? 171.206 156.486 121.080 1.00 72.15  ? 86  THR L OG1 1 
ATOM   6474 C  CG2 . THR C 3 86  ? 172.631 156.017 122.953 1.00 72.15  ? 86  THR L CG2 1 
ATOM   6475 N  N   . TYR C 3 87  ? 170.521 155.242 125.462 1.00 68.04  ? 87  TYR L N   1 
ATOM   6476 C  CA  . TYR C 3 87  ? 170.307 155.379 126.897 1.00 68.04  ? 87  TYR L CA  1 
ATOM   6477 C  C   . TYR C 3 87  ? 171.624 155.667 127.603 1.00 68.04  ? 87  TYR L C   1 
ATOM   6478 O  O   . TYR C 3 87  ? 172.644 155.036 127.308 1.00 68.04  ? 87  TYR L O   1 
ATOM   6479 C  CB  . TYR C 3 87  ? 169.662 154.117 127.476 1.00 68.04  ? 87  TYR L CB  1 
ATOM   6480 C  CG  . TYR C 3 87  ? 168.328 153.775 126.855 1.00 68.04  ? 87  TYR L CG  1 
ATOM   6481 C  CD1 . TYR C 3 87  ? 167.150 154.296 127.370 1.00 68.04  ? 87  TYR L CD1 1 
ATOM   6482 C  CD2 . TYR C 3 87  ? 168.244 152.929 125.759 1.00 68.04  ? 87  TYR L CD2 1 
ATOM   6483 C  CE1 . TYR C 3 87  ? 165.928 153.987 126.809 1.00 68.04  ? 87  TYR L CE1 1 
ATOM   6484 C  CE2 . TYR C 3 87  ? 167.026 152.616 125.191 1.00 68.04  ? 87  TYR L CE2 1 
ATOM   6485 C  CZ  . TYR C 3 87  ? 165.873 153.148 125.720 1.00 68.04  ? 87  TYR L CZ  1 
ATOM   6486 O  OH  . TYR C 3 87  ? 164.658 152.838 125.158 1.00 68.04  ? 87  TYR L OH  1 
ATOM   6487 N  N   . TYR C 3 88  ? 171.594 156.618 128.535 1.00 62.44  ? 88  TYR L N   1 
ATOM   6488 C  CA  . TYR C 3 88  ? 172.753 157.009 129.324 1.00 62.44  ? 88  TYR L CA  1 
ATOM   6489 C  C   . TYR C 3 88  ? 172.438 156.889 130.809 1.00 62.44  ? 88  TYR L C   1 
ATOM   6490 O  O   . TYR C 3 88  ? 171.275 156.931 131.219 1.00 62.44  ? 88  TYR L O   1 
ATOM   6491 C  CB  . TYR C 3 88  ? 173.190 158.448 129.016 1.00 62.44  ? 88  TYR L CB  1 
ATOM   6492 C  CG  . TYR C 3 88  ? 173.397 158.749 127.550 1.00 62.44  ? 88  TYR L CG  1 
ATOM   6493 C  CD1 . TYR C 3 88  ? 174.634 158.551 126.953 1.00 62.44  ? 88  TYR L CD1 1 
ATOM   6494 C  CD2 . TYR C 3 88  ? 172.364 159.240 126.767 1.00 62.44  ? 88  TYR L CD2 1 
ATOM   6495 C  CE1 . TYR C 3 88  ? 174.834 158.827 125.618 1.00 62.44  ? 88  TYR L CE1 1 
ATOM   6496 C  CE2 . TYR C 3 88  ? 172.554 159.517 125.430 1.00 62.44  ? 88  TYR L CE2 1 
ATOM   6497 C  CZ  . TYR C 3 88  ? 173.791 159.308 124.861 1.00 62.44  ? 88  TYR L CZ  1 
ATOM   6498 O  OH  . TYR C 3 88  ? 173.987 159.584 123.530 1.00 62.44  ? 88  TYR L OH  1 
ATOM   6499 N  N   . CYS C 3 89  ? 173.488 156.744 131.613 1.00 67.72  ? 89  CYS L N   1 
ATOM   6500 C  CA  . CYS C 3 89  ? 173.370 156.662 133.061 1.00 67.72  ? 89  CYS L CA  1 
ATOM   6501 C  C   . CYS C 3 89  ? 174.175 157.783 133.702 1.00 67.72  ? 89  CYS L C   1 
ATOM   6502 O  O   . CYS C 3 89  ? 175.313 158.048 133.304 1.00 67.72  ? 89  CYS L O   1 
ATOM   6503 C  CB  . CYS C 3 89  ? 173.846 155.300 133.589 1.00 67.72  ? 89  CYS L CB  1 
ATOM   6504 S  SG  . CYS C 3 89  ? 175.503 154.796 133.068 1.00 67.72  ? 89  CYS L SG  1 
ATOM   6505 N  N   . GLN C 3 90  ? 173.580 158.438 134.693 1.00 70.63  ? 90  GLN L N   1 
ATOM   6506 C  CA  . GLN C 3 90  ? 174.191 159.568 135.372 1.00 70.63  ? 90  GLN L CA  1 
ATOM   6507 C  C   . GLN C 3 90  ? 174.266 159.289 136.867 1.00 70.63  ? 90  GLN L C   1 
ATOM   6508 O  O   . GLN C 3 90  ? 173.625 158.369 137.375 1.00 70.63  ? 90  GLN L O   1 
ATOM   6509 C  CB  . GLN C 3 90  ? 173.396 160.854 135.120 1.00 70.63  ? 90  GLN L CB  1 
ATOM   6510 C  CG  . GLN C 3 90  ? 174.211 162.125 135.209 1.00 70.63  ? 90  GLN L CG  1 
ATOM   6511 C  CD  . GLN C 3 90  ? 173.347 163.353 135.291 1.00 70.63  ? 90  GLN L CD  1 
ATOM   6512 O  OE1 . GLN C 3 90  ? 172.131 163.260 135.447 1.00 70.63  ? 90  GLN L OE1 1 
ATOM   6513 N  NE2 . GLN C 3 90  ? 173.971 164.519 135.201 1.00 70.63  ? 90  GLN L NE2 1 
ATOM   6514 N  N   . GLN C 3 91  ? 175.066 160.089 137.571 1.00 66.77  ? 91  GLN L N   1 
ATOM   6515 C  CA  . GLN C 3 91  ? 175.169 160.011 139.020 1.00 66.77  ? 91  GLN L CA  1 
ATOM   6516 C  C   . GLN C 3 91  ? 175.331 161.411 139.597 1.00 66.77  ? 91  GLN L C   1 
ATOM   6517 O  O   . GLN C 3 91  ? 176.037 162.247 139.028 1.00 66.77  ? 91  GLN L O   1 
ATOM   6518 C  CB  . GLN C 3 91  ? 176.329 159.089 139.436 1.00 66.77  ? 91  GLN L CB  1 
ATOM   6519 C  CG  . GLN C 3 91  ? 177.702 159.442 138.868 1.00 66.77  ? 91  GLN L CG  1 
ATOM   6520 C  CD  . GLN C 3 91  ? 178.463 160.446 139.709 1.00 66.77  ? 91  GLN L CD  1 
ATOM   6521 O  OE1 . GLN C 3 91  ? 178.310 160.494 140.928 1.00 66.77  ? 91  GLN L OE1 1 
ATOM   6522 N  NE2 . GLN C 3 91  ? 179.293 161.251 139.060 1.00 66.77  ? 91  GLN L NE2 1 
ATOM   6523 N  N   . PHE C 3 92  ? 174.655 161.669 140.718 1.00 71.33  ? 92  PHE L N   1 
ATOM   6524 C  CA  . PHE C 3 92  ? 174.754 162.946 141.415 1.00 71.33  ? 92  PHE L CA  1 
ATOM   6525 C  C   . PHE C 3 92  ? 175.504 162.852 142.736 1.00 71.33  ? 92  PHE L C   1 
ATOM   6526 O  O   . PHE C 3 92  ? 175.567 163.846 143.466 1.00 71.33  ? 92  PHE L O   1 
ATOM   6527 C  CB  . PHE C 3 92  ? 173.369 163.539 141.681 1.00 71.33  ? 92  PHE L CB  1 
ATOM   6528 C  CG  . PHE C 3 92  ? 172.719 164.163 140.483 1.00 71.33  ? 92  PHE L CG  1 
ATOM   6529 C  CD1 . PHE C 3 92  ? 173.415 164.360 139.309 1.00 71.33  ? 92  PHE L CD1 1 
ATOM   6530 C  CD2 . PHE C 3 92  ? 171.413 164.603 140.557 1.00 71.33  ? 92  PHE L CD2 1 
ATOM   6531 C  CE1 . PHE C 3 92  ? 172.797 164.947 138.223 1.00 71.33  ? 92  PHE L CE1 1 
ATOM   6532 C  CE2 . PHE C 3 92  ? 170.798 165.197 139.481 1.00 71.33  ? 92  PHE L CE2 1 
ATOM   6533 C  CZ  . PHE C 3 92  ? 171.490 165.369 138.312 1.00 71.33  ? 92  PHE L CZ  1 
ATOM   6534 N  N   . SER C 3 93  ? 176.058 161.686 143.073 1.00 69.57  ? 93  SER L N   1 
ATOM   6535 C  CA  . SER C 3 93  ? 176.708 161.527 144.370 1.00 69.57  ? 93  SER L CA  1 
ATOM   6536 C  C   . SER C 3 93  ? 177.994 162.338 144.442 1.00 69.57  ? 93  SER L C   1 
ATOM   6537 O  O   . SER C 3 93  ? 178.126 163.246 145.271 1.00 69.57  ? 93  SER L O   1 
ATOM   6538 C  CB  . SER C 3 93  ? 176.986 160.049 144.642 1.00 69.57  ? 93  SER L CB  1 
ATOM   6539 O  OG  . SER C 3 93  ? 175.794 159.360 144.975 1.00 69.57  ? 93  SER L OG  1 
ATOM   6540 N  N   . GLY C 3 94  ? 178.948 162.036 143.573 1.00 64.20  ? 94  GLY L N   1 
ATOM   6541 C  CA  . GLY C 3 94  ? 180.220 162.727 143.553 1.00 64.20  ? 94  GLY L CA  1 
ATOM   6542 C  C   . GLY C 3 94  ? 180.306 163.728 142.417 1.00 64.20  ? 94  GLY L C   1 
ATOM   6543 O  O   . GLY C 3 94  ? 179.728 163.534 141.351 1.00 64.20  ? 94  GLY L O   1 
ATOM   6544 N  N   . TYR C 3 95  ? 181.034 164.810 142.664 1.00 60.54  ? 95  TYR L N   1 
ATOM   6545 C  CA  . TYR C 3 95  ? 181.302 165.794 141.635 1.00 60.54  ? 95  TYR L CA  1 
ATOM   6546 C  C   . TYR C 3 95  ? 182.721 165.618 141.108 1.00 60.54  ? 95  TYR L C   1 
ATOM   6547 O  O   . TYR C 3 95  ? 183.626 165.288 141.883 1.00 60.54  ? 95  TYR L O   1 
ATOM   6548 C  CB  . TYR C 3 95  ? 181.126 167.221 142.167 1.00 60.54  ? 95  TYR L CB  1 
ATOM   6549 C  CG  . TYR C 3 95  ? 179.694 167.705 142.139 1.00 60.54  ? 95  TYR L CG  1 
ATOM   6550 C  CD1 . TYR C 3 95  ? 178.718 167.095 142.915 1.00 60.54  ? 95  TYR L CD1 1 
ATOM   6551 C  CD2 . TYR C 3 95  ? 179.316 168.763 141.325 1.00 60.54  ? 95  TYR L CD2 1 
ATOM   6552 C  CE1 . TYR C 3 95  ? 177.408 167.535 142.888 1.00 60.54  ? 95  TYR L CE1 1 
ATOM   6553 C  CE2 . TYR C 3 95  ? 178.010 169.207 141.291 1.00 60.54  ? 95  TYR L CE2 1 
ATOM   6554 C  CZ  . TYR C 3 95  ? 177.062 168.591 142.074 1.00 60.54  ? 95  TYR L CZ  1 
ATOM   6555 O  OH  . TYR C 3 95  ? 175.762 169.032 142.041 1.00 60.54  ? 95  TYR L OH  1 
ATOM   6556 N  N   . PRO C 3 96  ? 182.962 165.823 139.804 1.00 64.00  ? 96  PRO L N   1 
ATOM   6557 C  CA  . PRO C 3 96  ? 182.042 166.275 138.751 1.00 64.00  ? 96  PRO L CA  1 
ATOM   6558 C  C   . PRO C 3 96  ? 181.080 165.202 138.256 1.00 64.00  ? 96  PRO L C   1 
ATOM   6559 O  O   . PRO C 3 96  ? 181.315 164.008 138.405 1.00 64.00  ? 96  PRO L O   1 
ATOM   6560 C  CB  . PRO C 3 96  ? 183.000 166.709 137.640 1.00 64.00  ? 96  PRO L CB  1 
ATOM   6561 C  CG  . PRO C 3 96  ? 184.148 165.766 137.777 1.00 64.00  ? 96  PRO L CG  1 
ATOM   6562 C  CD  . PRO C 3 96  ? 184.306 165.554 139.263 1.00 64.00  ? 96  PRO L CD  1 
ATOM   6563 N  N   . LEU C 3 97  ? 179.975 165.640 137.664 1.00 64.01  ? 97  LEU L N   1 
ATOM   6564 C  CA  . LEU C 3 97  ? 178.966 164.728 137.147 1.00 64.01  ? 97  LEU L CA  1 
ATOM   6565 C  C   . LEU C 3 97  ? 179.477 164.026 135.897 1.00 64.01  ? 97  LEU L C   1 
ATOM   6566 O  O   . LEU C 3 97  ? 180.162 164.625 135.065 1.00 64.01  ? 97  LEU L O   1 
ATOM   6567 C  CB  . LEU C 3 97  ? 177.692 165.500 136.827 1.00 64.01  ? 97  LEU L CB  1 
ATOM   6568 C  CG  . LEU C 3 97  ? 176.569 165.649 137.847 1.00 64.01  ? 97  LEU L CG  1 
ATOM   6569 C  CD1 . LEU C 3 97  ? 177.076 166.064 139.208 1.00 64.01  ? 97  LEU L CD1 1 
ATOM   6570 C  CD2 . LEU C 3 97  ? 175.661 166.726 137.308 1.00 64.01  ? 97  LEU L CD2 1 
ATOM   6571 N  N   . THR C 3 98  ? 179.142 162.746 135.768 1.00 67.48  ? 98  THR L N   1 
ATOM   6572 C  CA  . THR C 3 98  ? 179.578 161.938 134.640 1.00 67.48  ? 98  THR L CA  1 
ATOM   6573 C  C   . THR C 3 98  ? 178.385 161.234 134.014 1.00 67.48  ? 98  THR L C   1 
ATOM   6574 O  O   . THR C 3 98  ? 177.371 160.987 134.672 1.00 67.48  ? 98  THR L O   1 
ATOM   6575 C  CB  . THR C 3 98  ? 180.623 160.892 135.053 1.00 67.48  ? 98  THR L CB  1 
ATOM   6576 O  OG1 . THR C 3 98  ? 180.075 160.045 136.070 1.00 67.48  ? 98  THR L OG1 1 
ATOM   6577 C  CG2 . THR C 3 98  ? 181.892 161.555 135.569 1.00 67.48  ? 98  THR L CG2 1 
ATOM   6578 N  N   . PHE C 3 99  ? 178.517 160.915 132.732 1.00 63.51  ? 99  PHE L N   1 
ATOM   6579 C  CA  . PHE C 3 99  ? 177.523 160.157 131.992 1.00 63.51  ? 99  PHE L CA  1 
ATOM   6580 C  C   . PHE C 3 99  ? 178.150 158.876 131.462 1.00 63.51  ? 99  PHE L C   1 
ATOM   6581 O  O   . PHE C 3 99  ? 179.373 158.727 131.408 1.00 63.51  ? 99  PHE L O   1 
ATOM   6582 C  CB  . PHE C 3 99  ? 176.946 160.974 130.832 1.00 63.51  ? 99  PHE L CB  1 
ATOM   6583 C  CG  . PHE C 3 99  ? 175.949 162.011 131.251 1.00 63.51  ? 99  PHE L CG  1 
ATOM   6584 C  CD1 . PHE C 3 99  ? 176.362 163.216 131.787 1.00 63.51  ? 99  PHE L CD1 1 
ATOM   6585 C  CD2 . PHE C 3 99  ? 174.595 161.789 131.086 1.00 63.51  ? 99  PHE L CD2 1 
ATOM   6586 C  CE1 . PHE C 3 99  ? 175.442 164.172 132.164 1.00 63.51  ? 99  PHE L CE1 1 
ATOM   6587 C  CE2 . PHE C 3 99  ? 173.675 162.741 131.460 1.00 63.51  ? 99  PHE L CE2 1 
ATOM   6588 C  CZ  . PHE C 3 99  ? 174.097 163.933 131.996 1.00 63.51  ? 99  PHE L CZ  1 
ATOM   6589 N  N   . GLY C 3 100 ? 177.293 157.945 131.063 1.00 67.24  ? 100 GLY L N   1 
ATOM   6590 C  CA  . GLY C 3 100 ? 177.765 156.709 130.483 1.00 67.24  ? 100 GLY L CA  1 
ATOM   6591 C  C   . GLY C 3 100 ? 178.175 156.873 129.034 1.00 67.24  ? 100 GLY L C   1 
ATOM   6592 O  O   . GLY C 3 100 ? 177.997 157.923 128.417 1.00 67.24  ? 100 GLY L O   1 
ATOM   6593 N  N   . SER C 3 101 ? 178.745 155.800 128.485 1.00 75.10  ? 101 SER L N   1 
ATOM   6594 C  CA  . SER C 3 101 ? 179.129 155.804 127.080 1.00 75.10  ? 101 SER L CA  1 
ATOM   6595 C  C   . SER C 3 101 ? 177.922 155.762 126.154 1.00 75.10  ? 101 SER L C   1 
ATOM   6596 O  O   . SER C 3 101 ? 177.989 156.302 125.045 1.00 75.10  ? 101 SER L O   1 
ATOM   6597 C  CB  . SER C 3 101 ? 180.055 154.624 126.785 1.00 75.10  ? 101 SER L CB  1 
ATOM   6598 O  OG  . SER C 3 101 ? 179.310 153.467 126.449 1.00 75.10  ? 101 SER L OG  1 
ATOM   6599 N  N   . GLY C 3 102 ? 176.826 155.143 126.582 1.00 79.96  ? 102 GLY L N   1 
ATOM   6600 C  CA  . GLY C 3 102 ? 175.623 155.095 125.777 1.00 79.96  ? 102 GLY L CA  1 
ATOM   6601 C  C   . GLY C 3 102 ? 175.410 153.770 125.079 1.00 79.96  ? 102 GLY L C   1 
ATOM   6602 O  O   . GLY C 3 102 ? 176.242 153.348 124.271 1.00 79.96  ? 102 GLY L O   1 
ATOM   6603 N  N   . THR C 3 103 ? 174.302 153.100 125.382 1.00 79.06  ? 103 THR L N   1 
ATOM   6604 C  CA  . THR C 3 103 ? 173.905 151.881 124.689 1.00 79.06  ? 103 THR L CA  1 
ATOM   6605 C  C   . THR C 3 103 ? 172.876 152.248 123.631 1.00 79.06  ? 103 THR L C   1 
ATOM   6606 O  O   . THR C 3 103 ? 171.866 152.888 123.940 1.00 79.06  ? 103 THR L O   1 
ATOM   6607 C  CB  . THR C 3 103 ? 173.329 150.844 125.653 1.00 79.06  ? 103 THR L CB  1 
ATOM   6608 O  OG1 . THR C 3 103 ? 172.034 151.267 126.098 1.00 79.06  ? 103 THR L OG1 1 
ATOM   6609 C  CG2 . THR C 3 103 ? 174.241 150.653 126.851 1.00 79.06  ? 103 THR L CG2 1 
ATOM   6610 N  N   . LYS C 3 104 ? 173.134 151.848 122.392 1.00 84.69  ? 104 LYS L N   1 
ATOM   6611 C  CA  . LYS C 3 104 ? 172.237 152.140 121.283 1.00 84.69  ? 104 LYS L CA  1 
ATOM   6612 C  C   . LYS C 3 104 ? 171.284 150.967 121.087 1.00 84.69  ? 104 LYS L C   1 
ATOM   6613 O  O   . LYS C 3 104 ? 171.715 149.867 120.726 1.00 84.69  ? 104 LYS L O   1 
ATOM   6614 C  CB  . LYS C 3 104 ? 173.036 152.409 120.009 1.00 84.69  ? 104 LYS L CB  1 
ATOM   6615 C  CG  . LYS C 3 104 ? 172.193 152.826 118.817 1.00 84.69  ? 104 LYS L CG  1 
ATOM   6616 C  CD  . LYS C 3 104 ? 172.124 154.336 118.693 1.00 84.69  ? 104 LYS L CD  1 
ATOM   6617 C  CE  . LYS C 3 104 ? 171.468 154.745 117.387 1.00 84.69  ? 104 LYS L CE  1 
ATOM   6618 N  NZ  . LYS C 3 104 ? 172.025 153.985 116.235 1.00 84.69  ? 104 LYS L NZ  1 
ATOM   6619 N  N   . LEU C 3 105 ? 169.996 151.200 121.325 1.00 88.71  ? 105 LEU L N   1 
ATOM   6620 C  CA  . LEU C 3 105 ? 168.975 150.176 121.133 1.00 88.71  ? 105 LEU L CA  1 
ATOM   6621 C  C   . LEU C 3 105 ? 168.600 150.159 119.657 1.00 88.71  ? 105 LEU L C   1 
ATOM   6622 O  O   . LEU C 3 105 ? 168.025 151.123 119.143 1.00 88.71  ? 105 LEU L O   1 
ATOM   6623 C  CB  . LEU C 3 105 ? 167.762 150.445 122.022 1.00 88.71  ? 105 LEU L CB  1 
ATOM   6624 C  CG  . LEU C 3 105 ? 166.686 149.363 122.187 1.00 88.71  ? 105 LEU L CG  1 
ATOM   6625 C  CD1 . LEU C 3 105 ? 166.062 149.466 123.564 1.00 88.71  ? 105 LEU L CD1 1 
ATOM   6626 C  CD2 . LEU C 3 105 ? 165.592 149.458 121.132 1.00 88.71  ? 105 LEU L CD2 1 
ATOM   6627 N  N   . GLU C 3 106 ? 168.919 149.063 118.979 1.00 97.29  ? 106 GLU L N   1 
ATOM   6628 C  CA  . GLU C 3 106 ? 168.673 148.916 117.555 1.00 97.29  ? 106 GLU L CA  1 
ATOM   6629 C  C   . GLU C 3 106 ? 167.593 147.868 117.328 1.00 97.29  ? 106 GLU L C   1 
ATOM   6630 O  O   . GLU C 3 106 ? 167.220 147.122 118.237 1.00 97.29  ? 106 GLU L O   1 
ATOM   6631 C  CB  . GLU C 3 106 ? 169.961 148.518 116.828 1.00 97.29  ? 106 GLU L CB  1 
ATOM   6632 C  CG  . GLU C 3 106 ? 170.797 149.693 116.367 1.00 97.29  ? 106 GLU L CG  1 
ATOM   6633 C  CD  . GLU C 3 106 ? 170.131 150.479 115.273 1.00 97.29  ? 106 GLU L CD  1 
ATOM   6634 O  OE1 . GLU C 3 106 ? 170.074 149.951 114.149 1.00 97.29  ? 106 GLU L OE1 1 
ATOM   6635 O  OE2 . GLU C 3 106 ? 169.662 151.608 115.532 1.00 97.29  ? 106 GLU L OE2 1 
ATOM   6636 N  N   . MET C 3 107 ? 167.086 147.819 116.101 1.00 99.18  ? 107 MET L N   1 
ATOM   6637 C  CA  . MET C 3 107 ? 166.073 146.849 115.714 1.00 99.18  ? 107 MET L CA  1 
ATOM   6638 C  C   . MET C 3 107 ? 166.556 146.030 114.528 1.00 99.18  ? 107 MET L C   1 
ATOM   6639 O  O   . MET C 3 107 ? 167.339 146.511 113.703 1.00 99.18  ? 107 MET L O   1 
ATOM   6640 C  CB  . MET C 3 107 ? 164.745 147.524 115.363 1.00 99.18  ? 107 MET L CB  1 
ATOM   6641 C  CG  . MET C 3 107 ? 164.300 148.582 116.347 1.00 99.18  ? 107 MET L CG  1 
ATOM   6642 S  SD  . MET C 3 107 ? 163.718 147.814 117.866 1.00 99.18  ? 107 MET L SD  1 
ATOM   6643 C  CE  . MET C 3 107 ? 161.960 147.775 117.545 1.00 99.18  ? 107 MET L CE  1 
ATOM   6644 N  N   . LYS C 3 108 ? 166.087 144.788 114.454 1.00 95.08  ? 108 LYS L N   1 
ATOM   6645 C  CA  . LYS C 3 108 ? 166.360 143.911 113.329 1.00 95.08  ? 108 LYS L CA  1 
ATOM   6646 C  C   . LYS C 3 108 ? 165.048 143.368 112.781 1.00 95.08  ? 108 LYS L C   1 
ATOM   6647 O  O   . LYS C 3 108 ? 164.038 143.303 113.489 1.00 95.08  ? 108 LYS L O   1 
ATOM   6648 C  CB  . LYS C 3 108 ? 167.295 142.758 113.727 1.00 95.08  ? 108 LYS L CB  1 
ATOM   6649 C  CG  . LYS C 3 108 ? 166.624 141.612 114.462 1.00 95.08  ? 108 LYS L CG  1 
ATOM   6650 C  CD  . LYS C 3 108 ? 167.648 140.602 114.951 1.00 95.08  ? 108 LYS L CD  1 
ATOM   6651 C  CE  . LYS C 3 108 ? 168.549 141.208 116.009 1.00 95.08  ? 108 LYS L CE  1 
ATOM   6652 N  NZ  . LYS C 3 108 ? 167.761 141.980 117.007 1.00 95.08  ? 108 LYS L NZ  1 
ATOM   6653 N  N   . ARG C 3 109 ? 165.073 143.000 111.505 1.00 97.98  ? 109 ARG L N   1 
ATOM   6654 C  CA  . ARG C 3 109 ? 163.912 142.442 110.823 1.00 97.98  ? 109 ARG L CA  1 
ATOM   6655 C  C   . ARG C 3 109 ? 164.421 141.670 109.611 1.00 97.98  ? 109 ARG L C   1 
ATOM   6656 O  O   . ARG C 3 109 ? 165.631 141.538 109.406 1.00 97.98  ? 109 ARG L O   1 
ATOM   6657 C  CB  . ARG C 3 109 ? 162.899 143.542 110.463 1.00 97.98  ? 109 ARG L CB  1 
ATOM   6658 C  CG  . ARG C 3 109 ? 163.127 144.302 109.154 1.00 97.98  ? 109 ARG L CG  1 
ATOM   6659 C  CD  . ARG C 3 109 ? 164.317 145.238 109.202 1.00 97.98  ? 109 ARG L CD  1 
ATOM   6660 N  NE  . ARG C 3 109 ? 164.310 146.148 108.064 1.00 97.98  ? 109 ARG L NE  1 
ATOM   6661 C  CZ  . ARG C 3 109 ? 164.721 145.829 106.844 1.00 97.98  ? 109 ARG L CZ  1 
ATOM   6662 N  NH1 . ARG C 3 109 ? 165.214 144.632 106.570 1.00 97.98  ? 109 ARG L NH1 1 
ATOM   6663 N  NH2 . ARG C 3 109 ? 164.637 146.734 105.874 1.00 97.98  ? 109 ARG L NH2 1 
ATOM   6664 N  N   . ALA C 3 110 ? 163.485 141.120 108.832 1.00 101.76 ? 110 ALA L N   1 
ATOM   6665 C  CA  . ALA C 3 110 ? 163.833 140.420 107.601 1.00 101.76 ? 110 ALA L CA  1 
ATOM   6666 C  C   . ALA C 3 110 ? 164.571 141.349 106.644 1.00 101.76 ? 110 ALA L C   1 
ATOM   6667 O  O   . ALA C 3 110 ? 164.174 142.501 106.445 1.00 101.76 ? 110 ALA L O   1 
ATOM   6668 C  CB  . ALA C 3 110 ? 162.575 139.864 106.937 1.00 101.76 ? 110 ALA L CB  1 
ATOM   6669 N  N   . ASP C 3 111 ? 165.655 140.841 106.063 1.00 100.06 ? 111 ASP L N   1 
ATOM   6670 C  CA  . ASP C 3 111 ? 166.553 141.668 105.270 1.00 100.06 ? 111 ASP L CA  1 
ATOM   6671 C  C   . ASP C 3 111 ? 165.913 142.064 103.945 1.00 100.06 ? 111 ASP L C   1 
ATOM   6672 O  O   . ASP C 3 111 ? 165.261 141.253 103.282 1.00 100.06 ? 111 ASP L O   1 
ATOM   6673 C  CB  . ASP C 3 111 ? 167.860 140.920 105.016 1.00 100.06 ? 111 ASP L CB  1 
ATOM   6674 C  CG  . ASP C 3 111 ? 168.475 140.378 106.291 1.00 100.06 ? 111 ASP L CG  1 
ATOM   6675 O  OD1 . ASP C 3 111 ? 168.137 140.890 107.378 1.00 100.06 ? 111 ASP L OD1 1 
ATOM   6676 O  OD2 . ASP C 3 111 ? 169.296 139.440 106.206 1.00 100.06 ? 111 ASP L OD2 1 
ATOM   6677 N  N   . ALA C 3 112 ? 166.106 143.321 103.562 1.00 98.62  ? 112 ALA L N   1 
ATOM   6678 C  CA  . ALA C 3 112 ? 165.615 143.853 102.299 1.00 98.62  ? 112 ALA L CA  1 
ATOM   6679 C  C   . ALA C 3 112 ? 166.794 144.335 101.466 1.00 98.62  ? 112 ALA L C   1 
ATOM   6680 O  O   . ALA C 3 112 ? 167.723 144.954 101.997 1.00 98.62  ? 112 ALA L O   1 
ATOM   6681 C  CB  . ALA C 3 112 ? 164.621 144.994 102.531 1.00 98.62  ? 112 ALA L CB  1 
ATOM   6682 N  N   . ALA C 3 113 ? 166.755 144.043 100.169 1.00 95.52  ? 113 ALA L N   1 
ATOM   6683 C  CA  . ALA C 3 113 ? 167.860 144.391 99.287  1.00 95.52  ? 113 ALA L CA  1 
ATOM   6684 C  C   . ALA C 3 113 ? 167.923 145.904 99.081  1.00 95.52  ? 113 ALA L C   1 
ATOM   6685 O  O   . ALA C 3 113 ? 166.889 146.578 99.113  1.00 95.52  ? 113 ALA L O   1 
ATOM   6686 C  CB  . ALA C 3 113 ? 167.705 143.684 97.940  1.00 95.52  ? 113 ALA L CB  1 
ATOM   6687 N  N   . PRO C 3 114 ? 169.115 146.467 98.888  1.00 90.70  ? 114 PRO L N   1 
ATOM   6688 C  CA  . PRO C 3 114 ? 169.211 147.901 98.600  1.00 90.70  ? 114 PRO L CA  1 
ATOM   6689 C  C   . PRO C 3 114 ? 168.648 148.243 97.232  1.00 90.70  ? 114 PRO L C   1 
ATOM   6690 O  O   . PRO C 3 114 ? 168.660 147.431 96.304  1.00 90.70  ? 114 PRO L O   1 
ATOM   6691 C  CB  . PRO C 3 114 ? 170.718 148.176 98.659  1.00 90.70  ? 114 PRO L CB  1 
ATOM   6692 C  CG  . PRO C 3 114 ? 171.348 146.866 98.367  1.00 90.70  ? 114 PRO L CG  1 
ATOM   6693 C  CD  . PRO C 3 114 ? 170.443 145.838 98.983  1.00 90.70  ? 114 PRO L CD  1 
ATOM   6694 N  N   . THR C 3 115 ? 168.150 149.472 97.118  1.00 91.08  ? 115 THR L N   1 
ATOM   6695 C  CA  . THR C 3 115 ? 167.676 150.023 95.849  1.00 91.08  ? 115 THR L CA  1 
ATOM   6696 C  C   . THR C 3 115 ? 168.788 150.917 95.310  1.00 91.08  ? 115 THR L C   1 
ATOM   6697 O  O   . THR C 3 115 ? 168.791 152.132 95.513  1.00 91.08  ? 115 THR L O   1 
ATOM   6698 C  CB  . THR C 3 115 ? 166.371 150.786 96.034  1.00 91.08  ? 115 THR L CB  1 
ATOM   6699 O  OG1 . THR C 3 115 ? 166.540 151.781 97.050  1.00 91.08  ? 115 THR L OG1 1 
ATOM   6700 C  CG2 . THR C 3 115 ? 165.258 149.839 96.449  1.00 91.08  ? 115 THR L CG2 1 
ATOM   6701 N  N   . VAL C 3 116 ? 169.741 150.300 94.620  1.00 95.50  ? 116 VAL L N   1 
ATOM   6702 C  CA  . VAL C 3 116 ? 170.919 151.002 94.126  1.00 95.50  ? 116 VAL L CA  1 
ATOM   6703 C  C   . VAL C 3 116 ? 170.518 151.884 92.953  1.00 95.50  ? 116 VAL L C   1 
ATOM   6704 O  O   . VAL C 3 116 ? 169.882 151.420 91.999  1.00 95.50  ? 116 VAL L O   1 
ATOM   6705 C  CB  . VAL C 3 116 ? 172.011 150.001 93.718  1.00 95.50  ? 116 VAL L CB  1 
ATOM   6706 C  CG1 . VAL C 3 116 ? 173.228 150.728 93.173  1.00 95.50  ? 116 VAL L CG1 1 
ATOM   6707 C  CG2 . VAL C 3 116 ? 172.384 149.110 94.893  1.00 95.50  ? 116 VAL L CG2 1 
ATOM   6708 N  N   . SER C 3 117 ? 170.885 153.162 93.020  1.00 102.68 ? 117 SER L N   1 
ATOM   6709 C  CA  . SER C 3 117 ? 170.574 154.114 91.961  1.00 102.68 ? 117 SER L CA  1 
ATOM   6710 C  C   . SER C 3 117 ? 171.779 155.015 91.742  1.00 102.68 ? 117 SER L C   1 
ATOM   6711 O  O   . SER C 3 117 ? 172.137 155.799 92.627  1.00 102.68 ? 117 SER L O   1 
ATOM   6712 C  CB  . SER C 3 117 ? 169.338 154.944 92.314  1.00 102.68 ? 117 SER L CB  1 
ATOM   6713 O  OG  . SER C 3 117 ? 168.312 154.124 92.844  1.00 102.68 ? 117 SER L OG  1 
ATOM   6714 N  N   . ILE C 3 118 ? 172.397 154.906 90.571  1.00 116.22 ? 118 ILE L N   1 
ATOM   6715 C  CA  . ILE C 3 118 ? 173.561 155.713 90.224  1.00 116.22 ? 118 ILE L CA  1 
ATOM   6716 C  C   . ILE C 3 118 ? 173.081 157.034 89.632  1.00 116.22 ? 118 ILE L C   1 
ATOM   6717 O  O   . ILE C 3 118 ? 172.140 157.066 88.831  1.00 116.22 ? 118 ILE L O   1 
ATOM   6718 C  CB  . ILE C 3 118 ? 174.491 154.955 89.255  1.00 116.22 ? 118 ILE L CB  1 
ATOM   6719 C  CG1 . ILE C 3 118 ? 175.693 155.813 88.848  1.00 116.22 ? 118 ILE L CG1 1 
ATOM   6720 C  CG2 . ILE C 3 118 ? 173.737 154.432 88.032  1.00 116.22 ? 118 ILE L CG2 1 
ATOM   6721 C  CD1 . ILE C 3 118 ? 176.847 155.012 88.284  1.00 116.22 ? 118 ILE L CD1 1 
ATOM   6722 N  N   . PHE C 3 119 ? 173.687 158.130 90.070  1.00 113.00 ? 119 PHE L N   1 
ATOM   6723 C  CA  . PHE C 3 119 ? 173.326 159.462 89.584  1.00 113.00 ? 119 PHE L CA  1 
ATOM   6724 C  C   . PHE C 3 119 ? 174.531 160.104 88.918  1.00 113.00 ? 119 PHE L C   1 
ATOM   6725 O  O   . PHE C 3 119 ? 175.490 160.483 89.617  1.00 113.00 ? 119 PHE L O   1 
ATOM   6726 C  CB  . PHE C 3 119 ? 172.812 160.354 90.714  1.00 113.00 ? 119 PHE L CB  1 
ATOM   6727 C  CG  . PHE C 3 119 ? 171.421 160.020 91.182  1.00 113.00 ? 119 PHE L CG  1 
ATOM   6728 C  CD1 . PHE C 3 119 ? 171.143 158.818 91.815  1.00 113.00 ? 119 PHE L CD1 1 
ATOM   6729 C  CD2 . PHE C 3 119 ? 170.389 160.920 90.986  1.00 113.00 ? 119 PHE L CD2 1 
ATOM   6730 C  CE1 . PHE C 3 119 ? 169.866 158.524 92.241  1.00 113.00 ? 119 PHE L CE1 1 
ATOM   6731 C  CE2 . PHE C 3 119 ? 169.110 160.632 91.410  1.00 113.00 ? 119 PHE L CE2 1 
ATOM   6732 C  CZ  . PHE C 3 119 ? 168.849 159.432 92.038  1.00 113.00 ? 119 PHE L CZ  1 
ATOM   6733 N  N   . PRO C 3 120 ? 174.547 160.227 87.589  1.00 122.29 ? 120 PRO L N   1 
ATOM   6734 C  CA  . PRO C 3 120 ? 175.629 160.961 86.940  1.00 122.29 ? 120 PRO L CA  1 
ATOM   6735 C  C   . PRO C 3 120 ? 175.565 162.435 87.297  1.00 122.29 ? 120 PRO L C   1 
ATOM   6736 O  O   . PRO C 3 120 ? 174.479 162.973 87.572  1.00 122.29 ? 120 PRO L O   1 
ATOM   6737 C  CB  . PRO C 3 120 ? 175.363 160.735 85.440  1.00 122.29 ? 120 PRO L CB  1 
ATOM   6738 C  CG  . PRO C 3 120 ? 174.472 159.538 85.383  1.00 122.29 ? 120 PRO L CG  1 
ATOM   6739 C  CD  . PRO C 3 120 ? 173.628 159.621 86.613  1.00 122.29 ? 120 PRO L CD  1 
ATOM   6740 N  N   . PRO C 3 121 ? 176.704 163.123 87.329  1.00 124.80 ? 121 PRO L N   1 
ATOM   6741 C  CA  . PRO C 3 121 ? 176.690 164.555 87.646  1.00 124.80 ? 121 PRO L CA  1 
ATOM   6742 C  C   . PRO C 3 121 ? 176.019 165.369 86.551  1.00 124.80 ? 121 PRO L C   1 
ATOM   6743 O  O   . PRO C 3 121 ? 175.992 164.983 85.380  1.00 124.80 ? 121 PRO L O   1 
ATOM   6744 C  CB  . PRO C 3 121 ? 178.177 164.906 87.768  1.00 124.80 ? 121 PRO L CB  1 
ATOM   6745 C  CG  . PRO C 3 121 ? 178.875 163.874 86.952  1.00 124.80 ? 121 PRO L CG  1 
ATOM   6746 C  CD  . PRO C 3 121 ? 178.070 162.618 87.111  1.00 124.80 ? 121 PRO L CD  1 
ATOM   6747 N  N   . SER C 3 122 ? 175.464 166.509 86.954  1.00 131.64 ? 122 SER L N   1 
ATOM   6748 C  CA  . SER C 3 122 ? 174.772 167.391 86.030  1.00 131.64 ? 122 SER L CA  1 
ATOM   6749 C  C   . SER C 3 122 ? 175.772 168.150 85.160  1.00 131.64 ? 122 SER L C   1 
ATOM   6750 O  O   . SER C 3 122 ? 176.992 168.047 85.324  1.00 131.64 ? 122 SER L O   1 
ATOM   6751 C  CB  . SER C 3 122 ? 173.878 168.368 86.791  1.00 131.64 ? 122 SER L CB  1 
ATOM   6752 O  OG  . SER C 3 122 ? 174.592 169.001 87.838  1.00 131.64 ? 122 SER L OG  1 
ATOM   6753 N  N   . SER C 3 123 ? 175.231 168.923 84.213  1.00 131.17 ? 123 SER L N   1 
ATOM   6754 C  CA  . SER C 3 123 ? 176.074 169.685 83.297  1.00 131.17 ? 123 SER L CA  1 
ATOM   6755 C  C   . SER C 3 123 ? 176.833 170.792 84.016  1.00 131.17 ? 123 SER L C   1 
ATOM   6756 O  O   . SER C 3 123 ? 177.969 171.106 83.643  1.00 131.17 ? 123 SER L O   1 
ATOM   6757 C  CB  . SER C 3 123 ? 175.223 170.272 82.171  1.00 131.17 ? 123 SER L CB  1 
ATOM   6758 O  OG  . SER C 3 123 ? 174.383 169.285 81.599  1.00 131.17 ? 123 SER L OG  1 
ATOM   6759 N  N   . GLU C 3 124 ? 176.231 171.387 85.044  1.00 134.26 ? 124 GLU L N   1 
ATOM   6760 C  CA  . GLU C 3 124 ? 176.880 172.442 85.811  1.00 134.26 ? 124 GLU L CA  1 
ATOM   6761 C  C   . GLU C 3 124 ? 177.949 171.920 86.763  1.00 134.26 ? 124 GLU L C   1 
ATOM   6762 O  O   . GLU C 3 124 ? 178.693 172.728 87.329  1.00 134.26 ? 124 GLU L O   1 
ATOM   6763 C  CB  . GLU C 3 124 ? 175.822 173.243 86.582  1.00 134.26 ? 124 GLU L CB  1 
ATOM   6764 C  CG  . GLU C 3 124 ? 174.920 172.418 87.497  1.00 134.26 ? 124 GLU L CG  1 
ATOM   6765 C  CD  . GLU C 3 124 ? 175.498 172.207 88.883  1.00 134.26 ? 124 GLU L CD  1 
ATOM   6766 O  OE1 . GLU C 3 124 ? 176.423 172.953 89.265  1.00 134.26 ? 124 GLU L OE1 1 
ATOM   6767 O  OE2 . GLU C 3 124 ? 175.028 171.290 89.588  1.00 134.26 ? 124 GLU L OE2 1 
ATOM   6768 N  N   . GLN C 3 125 ? 178.035 170.602 86.963  1.00 136.06 ? 125 GLN L N   1 
ATOM   6769 C  CA  . GLN C 3 125 ? 179.038 170.054 87.869  1.00 136.06 ? 125 GLN L CA  1 
ATOM   6770 C  C   . GLN C 3 125 ? 180.443 170.180 87.293  1.00 136.06 ? 125 GLN L C   1 
ATOM   6771 O  O   . GLN C 3 125 ? 181.404 170.380 88.045  1.00 136.06 ? 125 GLN L O   1 
ATOM   6772 C  CB  . GLN C 3 125 ? 178.713 168.592 88.187  1.00 136.06 ? 125 GLN L CB  1 
ATOM   6773 C  CG  . GLN C 3 125 ? 179.458 168.025 89.391  1.00 136.06 ? 125 GLN L CG  1 
ATOM   6774 C  CD  . GLN C 3 125 ? 180.804 167.427 89.034  1.00 136.06 ? 125 GLN L CD  1 
ATOM   6775 O  OE1 . GLN C 3 125 ? 180.983 166.872 87.951  1.00 136.06 ? 125 GLN L OE1 1 
ATOM   6776 N  NE2 . GLN C 3 125 ? 181.768 167.566 89.936  1.00 136.06 ? 125 GLN L NE2 1 
ATOM   6777 N  N   . LEU C 3 126 ? 180.583 170.074 85.973  1.00 138.44 ? 126 LEU L N   1 
ATOM   6778 C  CA  . LEU C 3 126 ? 181.884 170.175 85.323  1.00 138.44 ? 126 LEU L CA  1 
ATOM   6779 C  C   . LEU C 3 126 ? 182.347 171.615 85.147  1.00 138.44 ? 126 LEU L C   1 
ATOM   6780 O  O   . LEU C 3 126 ? 183.471 171.832 84.680  1.00 138.44 ? 126 LEU L O   1 
ATOM   6781 C  CB  . LEU C 3 126 ? 181.859 169.476 83.958  1.00 138.44 ? 126 LEU L CB  1 
ATOM   6782 C  CG  . LEU C 3 126 ? 182.046 167.954 83.889  1.00 138.44 ? 126 LEU L CG  1 
ATOM   6783 C  CD1 . LEU C 3 126 ? 180.799 167.191 84.325  1.00 138.44 ? 126 LEU L CD1 1 
ATOM   6784 C  CD2 . LEU C 3 126 ? 182.470 167.534 82.488  1.00 138.44 ? 126 LEU L CD2 1 
ATOM   6785 N  N   . THR C 3 127 ? 181.508 172.596 85.490  1.00 135.54 ? 127 THR L N   1 
ATOM   6786 C  CA  . THR C 3 127 ? 181.926 173.993 85.424  1.00 135.54 ? 127 THR L CA  1 
ATOM   6787 C  C   . THR C 3 127 ? 183.008 174.295 86.453  1.00 135.54 ? 127 THR L C   1 
ATOM   6788 O  O   . THR C 3 127 ? 183.927 175.078 86.185  1.00 135.54 ? 127 THR L O   1 
ATOM   6789 C  CB  . THR C 3 127 ? 180.723 174.913 85.630  1.00 135.54 ? 127 THR L CB  1 
ATOM   6790 O  OG1 . THR C 3 127 ? 180.111 174.626 86.893  1.00 135.54 ? 127 THR L OG1 1 
ATOM   6791 C  CG2 . THR C 3 127 ? 179.701 174.707 84.523  1.00 135.54 ? 127 THR L CG2 1 
ATOM   6792 N  N   . SER C 3 128 ? 182.917 173.685 87.635  1.00 139.73 ? 128 SER L N   1 
ATOM   6793 C  CA  . SER C 3 128 ? 183.917 173.875 88.677  1.00 139.73 ? 128 SER L CA  1 
ATOM   6794 C  C   . SER C 3 128 ? 185.233 173.169 88.378  1.00 139.73 ? 128 SER L C   1 
ATOM   6795 O  O   . SER C 3 128 ? 186.255 173.526 88.972  1.00 139.73 ? 128 SER L O   1 
ATOM   6796 C  CB  . SER C 3 128 ? 183.372 173.391 90.023  1.00 139.73 ? 128 SER L CB  1 
ATOM   6797 N  N   . GLY C 3 129 ? 185.236 172.187 87.481  1.00 141.69 ? 129 GLY L N   1 
ATOM   6798 C  CA  . GLY C 3 129 ? 186.444 171.479 87.119  1.00 141.69 ? 129 GLY L CA  1 
ATOM   6799 C  C   . GLY C 3 129 ? 186.654 170.144 87.796  1.00 141.69 ? 129 GLY L C   1 
ATOM   6800 O  O   . GLY C 3 129 ? 187.719 169.543 87.617  1.00 141.69 ? 129 GLY L O   1 
ATOM   6801 N  N   . GLY C 3 130 ? 185.678 169.658 88.563  1.00 139.23 ? 130 GLY L N   1 
ATOM   6802 C  CA  . GLY C 3 130 ? 185.780 168.389 89.242  1.00 139.23 ? 130 GLY L CA  1 
ATOM   6803 C  C   . GLY C 3 130 ? 184.775 167.368 88.730  1.00 139.23 ? 130 GLY L C   1 
ATOM   6804 O  O   . GLY C 3 130 ? 183.940 167.635 87.870  1.00 139.23 ? 130 GLY L O   1 
ATOM   6805 N  N   . ALA C 3 131 ? 184.882 166.165 89.291  1.00 134.44 ? 131 ALA L N   1 
ATOM   6806 C  CA  . ALA C 3 131 ? 183.982 165.066 88.970  1.00 134.44 ? 131 ALA L CA  1 
ATOM   6807 C  C   . ALA C 3 131 ? 183.359 164.546 90.255  1.00 134.44 ? 131 ALA L C   1 
ATOM   6808 O  O   . ALA C 3 131 ? 184.074 164.107 91.162  1.00 134.44 ? 131 ALA L O   1 
ATOM   6809 C  CB  . ALA C 3 131 ? 184.717 163.937 88.241  1.00 134.44 ? 131 ALA L CB  1 
ATOM   6810 N  N   . SER C 3 132 ? 182.028 164.595 90.330  1.00 126.89 ? 132 SER L N   1 
ATOM   6811 C  CA  . SER C 3 132 ? 181.285 164.150 91.512  1.00 126.89 ? 132 SER L CA  1 
ATOM   6812 C  C   . SER C 3 132 ? 180.102 163.309 91.036  1.00 126.89 ? 132 SER L C   1 
ATOM   6813 O  O   . SER C 3 132 ? 179.005 163.829 90.817  1.00 126.89 ? 132 SER L O   1 
ATOM   6814 C  CB  . SER C 3 132 ? 180.830 165.332 92.357  1.00 126.89 ? 132 SER L CB  1 
ATOM   6815 O  OG  . SER C 3 132 ? 179.596 165.844 91.885  1.00 126.89 ? 132 SER L OG  1 
ATOM   6816 N  N   . VAL C 3 133 ? 180.334 162.009 90.880  1.00 117.68 ? 133 VAL L N   1 
ATOM   6817 C  CA  . VAL C 3 133 ? 179.276 161.048 90.591  1.00 117.68 ? 133 VAL L CA  1 
ATOM   6818 C  C   . VAL C 3 133 ? 178.877 160.386 91.904  1.00 117.68 ? 133 VAL L C   1 
ATOM   6819 O  O   . VAL C 3 133 ? 179.728 160.099 92.756  1.00 117.68 ? 133 VAL L O   1 
ATOM   6820 C  CB  . VAL C 3 133 ? 179.723 160.026 89.521  1.00 117.68 ? 133 VAL L CB  1 
ATOM   6821 C  CG1 . VAL C 3 133 ? 180.953 159.233 89.961  1.00 117.68 ? 133 VAL L CG1 1 
ATOM   6822 C  CG2 . VAL C 3 133 ? 178.579 159.095 89.139  1.00 117.68 ? 133 VAL L CG2 1 
ATOM   6823 N  N   . VAL C 3 134 ? 177.576 160.201 92.101  1.00 105.10 ? 134 VAL L N   1 
ATOM   6824 C  CA  . VAL C 3 134 ? 177.041 159.750 93.378  1.00 105.10 ? 134 VAL L CA  1 
ATOM   6825 C  C   . VAL C 3 134 ? 176.121 158.555 93.149  1.00 105.10 ? 134 VAL L C   1 
ATOM   6826 O  O   . VAL C 3 134 ? 175.359 158.516 92.177  1.00 105.10 ? 134 VAL L O   1 
ATOM   6827 C  CB  . VAL C 3 134 ? 176.326 160.910 94.115  1.00 105.10 ? 134 VAL L CB  1 
ATOM   6828 C  CG1 . VAL C 3 134 ? 175.191 161.489 93.286  1.00 105.10 ? 134 VAL L CG1 1 
ATOM   6829 C  CG2 . VAL C 3 134 ? 175.824 160.475 95.483  1.00 105.10 ? 134 VAL L CG2 1 
ATOM   6830 N  N   . CYS C 3 135 ? 176.239 157.553 94.018  1.00 97.34  ? 135 CYS L N   1 
ATOM   6831 C  CA  . CYS C 3 135 ? 175.360 156.391 94.025  1.00 97.34  ? 135 CYS L CA  1 
ATOM   6832 C  C   . CYS C 3 135 ? 174.576 156.386 95.327  1.00 97.34  ? 135 CYS L C   1 
ATOM   6833 O  O   . CYS C 3 135 ? 175.150 156.589 96.402  1.00 97.34  ? 135 CYS L O   1 
ATOM   6834 C  CB  . CYS C 3 135 ? 176.151 155.087 93.881  1.00 97.34  ? 135 CYS L CB  1 
ATOM   6835 S  SG  . CYS C 3 135 ? 176.693 154.707 92.201  1.00 97.34  ? 135 CYS L SG  1 
ATOM   6836 N  N   . PHE C 3 136 ? 173.271 156.157 95.231  1.00 88.34  ? 136 PHE L N   1 
ATOM   6837 C  CA  . PHE C 3 136 ? 172.394 156.136 96.391  1.00 88.34  ? 136 PHE L CA  1 
ATOM   6838 C  C   . PHE C 3 136 ? 171.986 154.704 96.706  1.00 88.34  ? 136 PHE L C   1 
ATOM   6839 O  O   . PHE C 3 136 ? 171.439 154.004 95.848  1.00 88.34  ? 136 PHE L O   1 
ATOM   6840 C  CB  . PHE C 3 136 ? 171.151 156.998 96.160  1.00 88.34  ? 136 PHE L CB  1 
ATOM   6841 C  CG  . PHE C 3 136 ? 171.405 158.471 96.275  1.00 88.34  ? 136 PHE L CG  1 
ATOM   6842 C  CD1 . PHE C 3 136 ? 171.898 159.189 95.200  1.00 88.34  ? 136 PHE L CD1 1 
ATOM   6843 C  CD2 . PHE C 3 136 ? 171.160 159.137 97.463  1.00 88.34  ? 136 PHE L CD2 1 
ATOM   6844 C  CE1 . PHE C 3 136 ? 172.132 160.548 95.304  1.00 88.34  ? 136 PHE L CE1 1 
ATOM   6845 C  CE2 . PHE C 3 136 ? 171.393 160.494 97.573  1.00 88.34  ? 136 PHE L CE2 1 
ATOM   6846 C  CZ  . PHE C 3 136 ? 171.881 161.199 96.493  1.00 88.34  ? 136 PHE L CZ  1 
ATOM   6847 N  N   . LEU C 3 137 ? 172.254 154.278 97.936  1.00 79.59  ? 137 LEU L N   1 
ATOM   6848 C  CA  . LEU C 3 137 ? 171.821 152.985 98.446  1.00 79.59  ? 137 LEU L CA  1 
ATOM   6849 C  C   . LEU C 3 137 ? 170.728 153.255 99.469  1.00 79.59  ? 137 LEU L C   1 
ATOM   6850 O  O   . LEU C 3 137 ? 170.967 153.945 100.465 1.00 79.59  ? 137 LEU L O   1 
ATOM   6851 C  CB  . LEU C 3 137 ? 172.987 152.225 99.082  1.00 79.59  ? 137 LEU L CB  1 
ATOM   6852 C  CG  . LEU C 3 137 ? 174.319 152.082 98.333  1.00 79.59  ? 137 LEU L CG  1 
ATOM   6853 C  CD1 . LEU C 3 137 ? 175.181 151.011 98.980  1.00 79.59  ? 137 LEU L CD1 1 
ATOM   6854 C  CD2 . LEU C 3 137 ? 174.115 151.761 96.863  1.00 79.59  ? 137 LEU L CD2 1 
ATOM   6855 N  N   . ASN C 3 138 ? 169.534 152.726 99.225  1.00 85.85  ? 138 ASN L N   1 
ATOM   6856 C  CA  . ASN C 3 138 ? 168.374 153.070 100.031 1.00 85.85  ? 138 ASN L CA  1 
ATOM   6857 C  C   . ASN C 3 138 ? 167.590 151.814 100.388 1.00 85.85  ? 138 ASN L C   1 
ATOM   6858 O  O   . ASN C 3 138 ? 167.486 150.888 99.576  1.00 85.85  ? 138 ASN L O   1 
ATOM   6859 C  CB  . ASN C 3 138 ? 167.479 154.069 99.285  1.00 85.85  ? 138 ASN L CB  1 
ATOM   6860 C  CG  . ASN C 3 138 ? 166.471 154.744 100.190 1.00 85.85  ? 138 ASN L CG  1 
ATOM   6861 O  OD1 . ASN C 3 138 ? 166.419 154.477 101.390 1.00 85.85  ? 138 ASN L OD1 1 
ATOM   6862 N  ND2 . ASN C 3 138 ? 165.664 155.630 99.619  1.00 85.85  ? 138 ASN L ND2 1 
ATOM   6863 N  N   . ASN C 3 139 ? 167.043 151.802 101.609 1.00 89.44  ? 139 ASN L N   1 
ATOM   6864 C  CA  . ASN C 3 139 ? 166.215 150.715 102.144 1.00 89.44  ? 139 ASN L CA  1 
ATOM   6865 C  C   . ASN C 3 139 ? 166.960 149.378 102.132 1.00 89.44  ? 139 ASN L C   1 
ATOM   6866 O  O   . ASN C 3 139 ? 166.607 148.440 101.415 1.00 89.44  ? 139 ASN L O   1 
ATOM   6867 C  CB  . ASN C 3 139 ? 164.879 150.615 101.400 1.00 89.44  ? 139 ASN L CB  1 
ATOM   6868 C  CG  . ASN C 3 139 ? 164.203 151.957 101.238 1.00 89.44  ? 139 ASN L CG  1 
ATOM   6869 O  OD1 . ASN C 3 139 ? 163.907 152.637 102.220 1.00 89.44  ? 139 ASN L OD1 1 
ATOM   6870 N  ND2 . ASN C 3 139 ? 163.950 152.347 99.995  1.00 89.44  ? 139 ASN L ND2 1 
ATOM   6871 N  N   . PHE C 3 140 ? 168.011 149.310 102.944 1.00 85.72  ? 140 PHE L N   1 
ATOM   6872 C  CA  . PHE C 3 140 ? 168.815 148.104 103.063 1.00 85.72  ? 140 PHE L CA  1 
ATOM   6873 C  C   . PHE C 3 140 ? 169.123 147.835 104.528 1.00 85.72  ? 140 PHE L C   1 
ATOM   6874 O  O   . PHE C 3 140 ? 169.153 148.752 105.352 1.00 85.72  ? 140 PHE L O   1 
ATOM   6875 C  CB  . PHE C 3 140 ? 170.114 148.214 102.254 1.00 85.72  ? 140 PHE L CB  1 
ATOM   6876 C  CG  . PHE C 3 140 ? 171.177 149.045 102.914 1.00 85.72  ? 140 PHE L CG  1 
ATOM   6877 C  CD1 . PHE C 3 140 ? 171.048 150.418 103.001 1.00 85.72  ? 140 PHE L CD1 1 
ATOM   6878 C  CD2 . PHE C 3 140 ? 172.315 148.453 103.433 1.00 85.72  ? 140 PHE L CD2 1 
ATOM   6879 C  CE1 . PHE C 3 140 ? 172.025 151.181 103.603 1.00 85.72  ? 140 PHE L CE1 1 
ATOM   6880 C  CE2 . PHE C 3 140 ? 173.295 149.213 104.035 1.00 85.72  ? 140 PHE L CE2 1 
ATOM   6881 C  CZ  . PHE C 3 140 ? 173.149 150.577 104.119 1.00 85.72  ? 140 PHE L CZ  1 
ATOM   6882 N  N   . TYR C 3 141 ? 169.348 146.557 104.842 1.00 94.69  ? 141 TYR L N   1 
ATOM   6883 C  CA  . TYR C 3 141 ? 169.683 146.103 106.181 1.00 94.69  ? 141 TYR L CA  1 
ATOM   6884 C  C   . TYR C 3 141 ? 170.628 144.919 106.042 1.00 94.69  ? 141 TYR L C   1 
ATOM   6885 O  O   . TYR C 3 141 ? 170.415 144.075 105.161 1.00 94.69  ? 141 TYR L O   1 
ATOM   6886 C  CB  . TYR C 3 141 ? 168.437 145.698 106.978 1.00 94.69  ? 141 TYR L CB  1 
ATOM   6887 C  CG  . TYR C 3 141 ? 168.697 145.494 108.452 1.00 94.69  ? 141 TYR L CG  1 
ATOM   6888 C  CD1 . TYR C 3 141 ? 168.699 146.567 109.330 1.00 94.69  ? 141 TYR L CD1 1 
ATOM   6889 C  CD2 . TYR C 3 141 ? 168.958 144.229 108.963 1.00 94.69  ? 141 TYR L CD2 1 
ATOM   6890 C  CE1 . TYR C 3 141 ? 168.947 146.388 110.677 1.00 94.69  ? 141 TYR L CE1 1 
ATOM   6891 C  CE2 . TYR C 3 141 ? 169.208 144.040 110.309 1.00 94.69  ? 141 TYR L CE2 1 
ATOM   6892 C  CZ  . TYR C 3 141 ? 169.200 145.123 111.160 1.00 94.69  ? 141 TYR L CZ  1 
ATOM   6893 O  OH  . TYR C 3 141 ? 169.446 144.945 112.501 1.00 94.69  ? 141 TYR L OH  1 
ATOM   6894 N  N   . PRO C 3 142 ? 171.670 144.820 106.880 1.00 93.93  ? 142 PRO L N   1 
ATOM   6895 C  CA  . PRO C 3 142 ? 172.066 145.722 107.967 1.00 93.93  ? 142 PRO L CA  1 
ATOM   6896 C  C   . PRO C 3 142 ? 173.076 146.782 107.549 1.00 93.93  ? 142 PRO L C   1 
ATOM   6897 O  O   . PRO C 3 142 ? 173.379 146.946 106.372 1.00 93.93  ? 142 PRO L O   1 
ATOM   6898 C  CB  . PRO C 3 142 ? 172.652 144.751 108.995 1.00 93.93  ? 142 PRO L CB  1 
ATOM   6899 C  CG  . PRO C 3 142 ? 173.297 143.678 108.151 1.00 93.93  ? 142 PRO L CG  1 
ATOM   6900 C  CD  . PRO C 3 142 ? 172.522 143.619 106.846 1.00 93.93  ? 142 PRO L CD  1 
ATOM   6901 N  N   . LYS C 3 143 ? 173.616 147.517 108.521 1.00 96.98  ? 143 LYS L N   1 
ATOM   6902 C  CA  . LYS C 3 143 ? 174.530 148.612 108.228 1.00 96.98  ? 143 LYS L CA  1 
ATOM   6903 C  C   . LYS C 3 143 ? 175.919 148.138 107.825 1.00 96.98  ? 143 LYS L C   1 
ATOM   6904 O  O   . LYS C 3 143 ? 176.697 148.935 107.291 1.00 96.98  ? 143 LYS L O   1 
ATOM   6905 C  CB  . LYS C 3 143 ? 174.640 149.539 109.440 1.00 96.98  ? 143 LYS L CB  1 
ATOM   6906 C  CG  . LYS C 3 143 ? 175.313 148.903 110.643 1.00 96.98  ? 143 LYS L CG  1 
ATOM   6907 C  CD  . LYS C 3 143 ? 175.363 149.863 111.819 1.00 96.98  ? 143 LYS L CD  1 
ATOM   6908 C  CE  . LYS C 3 143 ? 176.017 149.216 113.027 1.00 96.98  ? 143 LYS L CE  1 
ATOM   6909 N  NZ  . LYS C 3 143 ? 177.462 148.943 112.790 1.00 96.98  ? 143 LYS L NZ  1 
ATOM   6910 N  N   . ASP C 3 144 ? 176.249 146.868 108.060 1.00 103.56 ? 144 ASP L N   1 
ATOM   6911 C  CA  . ASP C 3 144 ? 177.573 146.337 107.733 1.00 103.56 ? 144 ASP L CA  1 
ATOM   6912 C  C   . ASP C 3 144 ? 177.596 145.952 106.257 1.00 103.56 ? 144 ASP L C   1 
ATOM   6913 O  O   . ASP C 3 144 ? 177.616 144.777 105.881 1.00 103.56 ? 144 ASP L O   1 
ATOM   6914 C  CB  . ASP C 3 144 ? 177.915 145.152 108.628 1.00 103.56 ? 144 ASP L CB  1 
ATOM   6915 C  CG  . ASP C 3 144 ? 178.150 145.559 110.070 1.00 103.56 ? 144 ASP L CG  1 
ATOM   6916 O  OD1 . ASP C 3 144 ? 178.587 146.705 110.303 1.00 103.56 ? 144 ASP L OD1 1 
ATOM   6917 O  OD2 . ASP C 3 144 ? 177.898 144.731 110.971 1.00 103.56 ? 144 ASP L OD2 1 
ATOM   6918 N  N   . ILE C 3 145 ? 177.600 146.974 105.404 1.00 103.32 ? 145 ILE L N   1 
ATOM   6919 C  CA  . ILE C 3 145 ? 177.594 146.799 103.957 1.00 103.32 ? 145 ILE L CA  1 
ATOM   6920 C  C   . ILE C 3 145 ? 178.737 147.615 103.371 1.00 103.32 ? 145 ILE L C   1 
ATOM   6921 O  O   . ILE C 3 145 ? 178.826 148.825 103.606 1.00 103.32 ? 145 ILE L O   1 
ATOM   6922 C  CB  . ILE C 3 145 ? 176.248 147.220 103.338 1.00 103.32 ? 145 ILE L CB  1 
ATOM   6923 C  CG1 . ILE C 3 145 ? 175.161 146.204 103.692 1.00 103.32 ? 145 ILE L CG1 1 
ATOM   6924 C  CG2 . ILE C 3 145 ? 176.366 147.370 101.828 1.00 103.32 ? 145 ILE L CG2 1 
ATOM   6925 C  CD1 . ILE C 3 145 ? 175.503 144.786 103.324 1.00 103.32 ? 145 ILE L CD1 1 
ATOM   6926 N  N   . ASN C 3 146 ? 179.605 146.955 102.611 1.00 116.09 ? 146 ASN L N   1 
ATOM   6927 C  CA  . ASN C 3 146 ? 180.749 147.598 101.983 1.00 116.09 ? 146 ASN L CA  1 
ATOM   6928 C  C   . ASN C 3 146 ? 180.413 147.961 100.543 1.00 116.09 ? 146 ASN L C   1 
ATOM   6929 O  O   . ASN C 3 146 ? 179.688 147.232 99.860  1.00 116.09 ? 146 ASN L O   1 
ATOM   6930 C  CB  . ASN C 3 146 ? 181.975 146.683 102.020 1.00 116.09 ? 146 ASN L CB  1 
ATOM   6931 C  CG  . ASN C 3 146 ? 183.281 147.453 101.957 1.00 116.09 ? 146 ASN L CG  1 
ATOM   6932 O  OD1 . ASN C 3 146 ? 183.510 148.236 101.034 1.00 116.09 ? 146 ASN L OD1 1 
ATOM   6933 N  ND2 . ASN C 3 146 ? 184.144 147.234 102.941 1.00 116.09 ? 146 ASN L ND2 1 
ATOM   6934 N  N   . VAL C 3 147 ? 180.943 149.093 100.089 1.00 112.71 ? 147 VAL L N   1 
ATOM   6935 C  CA  . VAL C 3 147 ? 180.742 149.572 98.728  1.00 112.71 ? 147 VAL L CA  1 
ATOM   6936 C  C   . VAL C 3 147 ? 182.105 149.896 98.130  1.00 112.71 ? 147 VAL L C   1 
ATOM   6937 O  O   . VAL C 3 147 ? 183.021 150.326 98.841  1.00 112.71 ? 147 VAL L O   1 
ATOM   6938 C  CB  . VAL C 3 147 ? 179.790 150.794 98.693  1.00 112.71 ? 147 VAL L CB  1 
ATOM   6939 C  CG1 . VAL C 3 147 ? 180.383 151.998 99.424  1.00 112.71 ? 147 VAL L CG1 1 
ATOM   6940 C  CG2 . VAL C 3 147 ? 179.398 151.158 97.262  1.00 112.71 ? 147 VAL L CG2 1 
ATOM   6941 N  N   . LYS C 3 148 ? 182.261 149.628 96.836  1.00 120.09 ? 148 LYS L N   1 
ATOM   6942 C  CA  . LYS C 3 148 ? 183.474 149.989 96.121  1.00 120.09 ? 148 LYS L CA  1 
ATOM   6943 C  C   . LYS C 3 148 ? 183.092 150.567 94.767  1.00 120.09 ? 148 LYS L C   1 
ATOM   6944 O  O   . LYS C 3 148 ? 182.021 150.281 94.225  1.00 120.09 ? 148 LYS L O   1 
ATOM   6945 C  CB  . LYS C 3 148 ? 184.430 148.787 95.976  1.00 120.09 ? 148 LYS L CB  1 
ATOM   6946 C  CG  . LYS C 3 148 ? 183.939 147.632 95.103  1.00 120.09 ? 148 LYS L CG  1 
ATOM   6947 C  CD  . LYS C 3 148 ? 184.547 147.671 93.702  1.00 120.09 ? 148 LYS L CD  1 
ATOM   6948 C  CE  . LYS C 3 148 ? 184.159 146.448 92.889  1.00 120.09 ? 148 LYS L CE  1 
ATOM   6949 N  NZ  . LYS C 3 148 ? 184.724 146.491 91.513  1.00 120.09 ? 148 LYS L NZ  1 
ATOM   6950 N  N   . TRP C 3 149 ? 183.984 151.392 94.230  1.00 120.01 ? 149 TRP L N   1 
ATOM   6951 C  CA  . TRP C 3 149 ? 183.790 152.042 92.943  1.00 120.01 ? 149 TRP L CA  1 
ATOM   6952 C  C   . TRP C 3 149 ? 184.613 151.316 91.889  1.00 120.01 ? 149 TRP L C   1 
ATOM   6953 O  O   . TRP C 3 149 ? 185.802 151.055 92.095  1.00 120.01 ? 149 TRP L O   1 
ATOM   6954 C  CB  . TRP C 3 149 ? 184.190 153.517 93.010  1.00 120.01 ? 149 TRP L CB  1 
ATOM   6955 C  CG  . TRP C 3 149 ? 183.242 154.365 93.804  1.00 120.01 ? 149 TRP L CG  1 
ATOM   6956 C  CD1 . TRP C 3 149 ? 183.320 154.655 95.134  1.00 120.01 ? 149 TRP L CD1 1 
ATOM   6957 C  CD2 . TRP C 3 149 ? 182.087 155.052 93.311  1.00 120.01 ? 149 TRP L CD2 1 
ATOM   6958 N  NE1 . TRP C 3 149 ? 182.278 155.469 95.503  1.00 120.01 ? 149 TRP L NE1 1 
ATOM   6959 C  CE2 . TRP C 3 149 ? 181.507 155.729 94.402  1.00 120.01 ? 149 TRP L CE2 1 
ATOM   6960 C  CE3 . TRP C 3 149 ? 181.483 155.157 92.055  1.00 120.01 ? 149 TRP L CE3 1 
ATOM   6961 C  CZ2 . TRP C 3 149 ? 180.354 156.498 94.275  1.00 120.01 ? 149 TRP L CZ2 1 
ATOM   6962 C  CZ3 . TRP C 3 149 ? 180.338 155.920 91.931  1.00 120.01 ? 149 TRP L CZ3 1 
ATOM   6963 C  CH2 . TRP C 3 149 ? 179.786 156.581 93.034  1.00 120.01 ? 149 TRP L CH2 1 
ATOM   6964 N  N   . LYS C 3 150 ? 183.977 150.988 90.770  1.00 131.48 ? 150 LYS L N   1 
ATOM   6965 C  CA  . LYS C 3 150 ? 184.617 150.275 89.672  1.00 131.48 ? 150 LYS L CA  1 
ATOM   6966 C  C   . LYS C 3 150 ? 184.785 151.247 88.511  1.00 131.48 ? 150 LYS L C   1 
ATOM   6967 O  O   . LYS C 3 150 ? 183.804 151.834 88.040  1.00 131.48 ? 150 LYS L O   1 
ATOM   6968 C  CB  . LYS C 3 150 ? 183.785 149.053 89.274  1.00 131.48 ? 150 LYS L CB  1 
ATOM   6969 C  CG  . LYS C 3 150 ? 183.946 148.561 87.841  1.00 131.48 ? 150 LYS L CG  1 
ATOM   6970 C  CD  . LYS C 3 150 ? 185.311 147.945 87.586  1.00 131.48 ? 150 LYS L CD  1 
ATOM   6971 C  CE  . LYS C 3 150 ? 185.504 147.683 86.104  1.00 131.48 ? 150 LYS L CE  1 
ATOM   6972 N  NZ  . LYS C 3 150 ? 185.628 148.954 85.345  1.00 131.48 ? 150 LYS L NZ  1 
ATOM   6973 N  N   . ILE C 3 151 ? 186.027 151.428 88.065  1.00 137.04 ? 151 ILE L N   1 
ATOM   6974 C  CA  . ILE C 3 151 ? 186.354 152.383 87.013  1.00 137.04 ? 151 ILE L CA  1 
ATOM   6975 C  C   . ILE C 3 151 ? 187.328 151.733 86.039  1.00 137.04 ? 151 ILE L C   1 
ATOM   6976 O  O   . ILE C 3 151 ? 188.249 151.021 86.453  1.00 137.04 ? 151 ILE L O   1 
ATOM   6977 C  CB  . ILE C 3 151 ? 186.948 153.687 87.587  1.00 137.04 ? 151 ILE L CB  1 
ATOM   6978 C  CG1 . ILE C 3 151 ? 187.971 153.380 88.682  1.00 137.04 ? 151 ILE L CG1 1 
ATOM   6979 C  CG2 . ILE C 3 151 ? 185.847 154.586 88.121  1.00 137.04 ? 151 ILE L CG2 1 
ATOM   6980 C  CD1 . ILE C 3 151 ? 188.818 154.573 89.072  1.00 137.04 ? 151 ILE L CD1 1 
ATOM   6981 N  N   . ASP C 3 152 ? 187.110 151.984 84.742  1.00 139.36 ? 152 ASP L N   1 
ATOM   6982 C  CA  . ASP C 3 152 ? 187.954 151.508 83.647  1.00 139.36 ? 152 ASP L CA  1 
ATOM   6983 C  C   . ASP C 3 152 ? 188.083 149.989 83.653  1.00 139.36 ? 152 ASP L C   1 
ATOM   6984 O  O   . ASP C 3 152 ? 187.225 149.284 83.113  1.00 139.36 ? 152 ASP L O   1 
ATOM   6985 C  CB  . ASP C 3 152 ? 189.338 152.164 83.700  1.00 139.36 ? 152 ASP L CB  1 
ATOM   6986 N  N   . GLY C 3 153 ? 189.153 149.480 84.259  1.00 142.63 ? 153 GLY L N   1 
ATOM   6987 C  CA  . GLY C 3 153 ? 189.350 148.048 84.368  1.00 142.63 ? 153 GLY L CA  1 
ATOM   6988 C  C   . GLY C 3 153 ? 189.880 147.618 85.721  1.00 142.63 ? 153 GLY L C   1 
ATOM   6989 O  O   . GLY C 3 153 ? 190.569 146.599 85.826  1.00 142.63 ? 153 GLY L O   1 
ATOM   6990 N  N   . SER C 3 154 ? 189.564 148.381 86.763  1.00 142.78 ? 154 SER L N   1 
ATOM   6991 C  CA  . SER C 3 154 ? 190.044 148.088 88.108  1.00 142.78 ? 154 SER L CA  1 
ATOM   6992 C  C   . SER C 3 154 ? 189.072 148.694 89.113  1.00 142.78 ? 154 SER L C   1 
ATOM   6993 O  O   . SER C 3 154 ? 188.083 149.333 88.746  1.00 142.78 ? 154 SER L O   1 
ATOM   6994 C  CB  . SER C 3 154 ? 191.466 148.617 88.315  1.00 142.78 ? 154 SER L CB  1 
ATOM   6995 O  OG  . SER C 3 154 ? 191.517 150.021 88.132  1.00 142.78 ? 154 SER L OG  1 
ATOM   6996 N  N   . GLU C 3 155 ? 189.363 148.485 90.392  1.00 134.74 ? 155 GLU L N   1 
ATOM   6997 C  CA  . GLU C 3 155 ? 188.575 149.049 91.476  1.00 134.74 ? 155 GLU L CA  1 
ATOM   6998 C  C   . GLU C 3 155 ? 189.160 150.388 91.909  1.00 134.74 ? 155 GLU L C   1 
ATOM   6999 O  O   . GLU C 3 155 ? 190.294 150.737 91.572  1.00 134.74 ? 155 GLU L O   1 
ATOM   7000 C  CB  . GLU C 3 155 ? 188.520 148.089 92.667  1.00 134.74 ? 155 GLU L CB  1 
ATOM   7001 C  CG  . GLU C 3 155 ? 189.883 147.677 93.196  1.00 134.74 ? 155 GLU L CG  1 
ATOM   7002 C  CD  . GLU C 3 155 ? 189.796 146.587 94.246  1.00 134.74 ? 155 GLU L CD  1 
ATOM   7003 O  OE1 . GLU C 3 155 ? 188.667 146.183 94.594  1.00 134.74 ? 155 GLU L OE1 1 
ATOM   7004 O  OE2 . GLU C 3 155 ? 190.858 146.135 94.724  1.00 134.74 ? 155 GLU L OE2 1 
ATOM   7005 N  N   . ARG C 3 156 ? 188.364 151.141 92.661  1.00 129.62 ? 156 ARG L N   1 
ATOM   7006 C  CA  . ARG C 3 156 ? 188.762 152.451 93.153  1.00 129.62 ? 156 ARG L CA  1 
ATOM   7007 C  C   . ARG C 3 156 ? 188.650 152.490 94.669  1.00 129.62 ? 156 ARG L C   1 
ATOM   7008 O  O   . ARG C 3 156 ? 187.639 152.067 95.239  1.00 129.62 ? 156 ARG L O   1 
ATOM   7009 C  CB  . ARG C 3 156 ? 187.905 153.560 92.534  1.00 129.62 ? 156 ARG L CB  1 
ATOM   7010 C  CG  . ARG C 3 156 ? 188.310 154.964 92.948  1.00 129.62 ? 156 ARG L CG  1 
ATOM   7011 C  CD  . ARG C 3 156 ? 189.790 155.204 92.699  1.00 129.62 ? 156 ARG L CD  1 
ATOM   7012 N  NE  . ARG C 3 156 ? 190.235 156.478 93.248  1.00 129.62 ? 156 ARG L NE  1 
ATOM   7013 C  CZ  . ARG C 3 156 ? 190.227 157.621 92.577  1.00 129.62 ? 156 ARG L CZ  1 
ATOM   7014 N  NH1 . ARG C 3 156 ? 189.811 157.682 91.323  1.00 129.62 ? 156 ARG L NH1 1 
ATOM   7015 N  NH2 . ARG C 3 156 ? 190.649 158.730 93.178  1.00 129.62 ? 156 ARG L NH2 1 
ATOM   7016 N  N   . GLN C 3 157 ? 189.694 152.996 95.314  1.00 133.52 ? 157 GLN L N   1 
ATOM   7017 C  CA  . GLN C 3 157 ? 189.740 153.151 96.762  1.00 133.52 ? 157 GLN L CA  1 
ATOM   7018 C  C   . GLN C 3 157 ? 189.798 154.605 97.199  1.00 133.52 ? 157 GLN L C   1 
ATOM   7019 O  O   . GLN C 3 157 ? 189.201 154.964 98.218  1.00 133.52 ? 157 GLN L O   1 
ATOM   7020 C  CB  . GLN C 3 157 ? 190.952 152.390 97.327  1.00 133.52 ? 157 GLN L CB  1 
ATOM   7021 C  CG  . GLN C 3 157 ? 191.051 152.382 98.845  1.00 133.52 ? 157 GLN L CG  1 
ATOM   7022 C  CD  . GLN C 3 157 ? 189.869 151.698 99.501  1.00 133.52 ? 157 GLN L CD  1 
ATOM   7023 O  OE1 . GLN C 3 157 ? 188.982 152.354 100.048 1.00 133.52 ? 157 GLN L OE1 1 
ATOM   7024 N  NE2 . GLN C 3 157 ? 189.850 150.371 99.450  1.00 133.52 ? 157 GLN L NE2 1 
ATOM   7025 N  N   . ASN C 3 158 ? 190.488 155.455 96.445  1.00 127.55 ? 158 ASN L N   1 
ATOM   7026 C  CA  . ASN C 3 158 ? 190.638 156.855 96.811  1.00 127.55 ? 158 ASN L CA  1 
ATOM   7027 C  C   . ASN C 3 158 ? 189.398 157.654 96.430  1.00 127.55 ? 158 ASN L C   1 
ATOM   7028 O  O   . ASN C 3 158 ? 188.729 157.370 95.432  1.00 127.55 ? 158 ASN L O   1 
ATOM   7029 C  CB  . ASN C 3 158 ? 191.870 157.454 96.132  1.00 127.55 ? 158 ASN L CB  1 
ATOM   7030 C  CG  . ASN C 3 158 ? 192.327 158.743 96.784  1.00 127.55 ? 158 ASN L CG  1 
ATOM   7031 O  OD1 . ASN C 3 158 ? 191.759 159.184 97.783  1.00 127.55 ? 158 ASN L OD1 1 
ATOM   7032 N  ND2 . ASN C 3 158 ? 193.361 159.356 96.220  1.00 127.55 ? 158 ASN L ND2 1 
ATOM   7033 N  N   . GLY C 3 159 ? 189.104 158.668 97.238  1.00 119.18 ? 159 GLY L N   1 
ATOM   7034 C  CA  . GLY C 3 159 ? 187.992 159.567 96.975  1.00 119.18 ? 159 GLY L CA  1 
ATOM   7035 C  C   . GLY C 3 159 ? 186.614 158.947 97.066  1.00 119.18 ? 159 GLY L C   1 
ATOM   7036 O  O   . GLY C 3 159 ? 185.768 159.202 96.200  1.00 119.18 ? 159 GLY L O   1 
ATOM   7037 N  N   . VAL C 3 160 ? 186.363 158.144 98.096  1.00 112.98 ? 160 VAL L N   1 
ATOM   7038 C  CA  . VAL C 3 160 ? 185.082 157.473 98.287  1.00 112.98 ? 160 VAL L CA  1 
ATOM   7039 C  C   . VAL C 3 160 ? 184.389 158.096 99.489  1.00 112.98 ? 160 VAL L C   1 
ATOM   7040 O  O   . VAL C 3 160 ? 184.962 158.152 100.584 1.00 112.98 ? 160 VAL L O   1 
ATOM   7041 C  CB  . VAL C 3 160 ? 185.263 155.958 98.480  1.00 112.98 ? 160 VAL L CB  1 
ATOM   7042 C  CG1 . VAL C 3 160 ? 183.913 155.280 98.659  1.00 112.98 ? 160 VAL L CG1 1 
ATOM   7043 C  CG2 . VAL C 3 160 ? 186.021 155.360 97.306  1.00 112.98 ? 160 VAL L CG2 1 
ATOM   7044 N  N   . LEU C 3 161 ? 183.160 158.560 99.287  1.00 99.98  ? 161 LEU L N   1 
ATOM   7045 C  CA  . LEU C 3 161 ? 182.394 159.191 100.349 1.00 99.98  ? 161 LEU L CA  1 
ATOM   7046 C  C   . LEU C 3 161 ? 181.524 158.165 101.067 1.00 99.98  ? 161 LEU L C   1 
ATOM   7047 O  O   . LEU C 3 161 ? 181.146 157.132 100.511 1.00 99.98  ? 161 LEU L O   1 
ATOM   7048 C  CB  . LEU C 3 161 ? 181.525 160.318 99.793  1.00 99.98  ? 161 LEU L CB  1 
ATOM   7049 C  CG  . LEU C 3 161 ? 181.237 161.465 100.760 1.00 99.98  ? 161 LEU L CG  1 
ATOM   7050 C  CD1 . LEU C 3 161 ? 182.545 162.027 101.273 1.00 99.98  ? 161 LEU L CD1 1 
ATOM   7051 C  CD2 . LEU C 3 161 ? 180.411 162.548 100.093 1.00 99.98  ? 161 LEU L CD2 1 
ATOM   7052 N  N   . ASN C 3 162 ? 181.209 158.466 102.323 1.00 86.83  ? 162 ASN L N   1 
ATOM   7053 C  CA  . ASN C 3 162 ? 180.420 157.575 103.158 1.00 86.83  ? 162 ASN L CA  1 
ATOM   7054 C  C   . ASN C 3 162 ? 179.438 158.392 103.982 1.00 86.83  ? 162 ASN L C   1 
ATOM   7055 O  O   . ASN C 3 162 ? 179.809 159.412 104.570 1.00 86.83  ? 162 ASN L O   1 
ATOM   7056 C  CB  . ASN C 3 162 ? 181.320 156.745 104.080 1.00 86.83  ? 162 ASN L CB  1 
ATOM   7057 C  CG  . ASN C 3 162 ? 180.675 155.448 104.507 1.00 86.83  ? 162 ASN L CG  1 
ATOM   7058 O  OD1 . ASN C 3 162 ? 179.557 155.436 105.018 1.00 86.83  ? 162 ASN L OD1 1 
ATOM   7059 N  ND2 . ASN C 3 162 ? 181.375 154.341 104.290 1.00 86.83  ? 162 ASN L ND2 1 
ATOM   7060 N  N   . SER C 3 163 ? 178.188 157.938 104.024 1.00 80.67  ? 163 SER L N   1 
ATOM   7061 C  CA  . SER C 3 163 ? 177.159 158.614 104.810 1.00 80.67  ? 163 SER L CA  1 
ATOM   7062 C  C   . SER C 3 163 ? 176.075 157.606 105.152 1.00 80.67  ? 163 SER L C   1 
ATOM   7063 O  O   . SER C 3 163 ? 175.237 157.292 104.301 1.00 80.67  ? 163 SER L O   1 
ATOM   7064 C  CB  . SER C 3 163 ? 176.572 159.794 104.041 1.00 80.67  ? 163 SER L CB  1 
ATOM   7065 O  OG  . SER C 3 163 ? 177.499 160.861 103.960 1.00 80.67  ? 163 SER L OG  1 
ATOM   7066 N  N   . TRP C 3 164 ? 176.083 157.106 106.383 1.00 78.17  ? 164 TRP L N   1 
ATOM   7067 C  CA  . TRP C 3 164 ? 175.070 156.168 106.844 1.00 78.17  ? 164 TRP L CA  1 
ATOM   7068 C  C   . TRP C 3 164 ? 173.927 156.935 107.491 1.00 78.17  ? 164 TRP L C   1 
ATOM   7069 O  O   . TRP C 3 164 ? 174.153 157.780 108.361 1.00 78.17  ? 164 TRP L O   1 
ATOM   7070 C  CB  . TRP C 3 164 ? 175.642 155.165 107.846 1.00 78.17  ? 164 TRP L CB  1 
ATOM   7071 C  CG  . TRP C 3 164 ? 176.608 154.188 107.268 1.00 78.17  ? 164 TRP L CG  1 
ATOM   7072 C  CD1 . TRP C 3 164 ? 176.316 153.115 106.479 1.00 78.17  ? 164 TRP L CD1 1 
ATOM   7073 C  CD2 . TRP C 3 164 ? 178.024 154.165 107.471 1.00 78.17  ? 164 TRP L CD2 1 
ATOM   7074 N  NE1 . TRP C 3 164 ? 177.467 152.439 106.158 1.00 78.17  ? 164 TRP L NE1 1 
ATOM   7075 C  CE2 . TRP C 3 164 ? 178.529 153.062 106.758 1.00 78.17  ? 164 TRP L CE2 1 
ATOM   7076 C  CE3 . TRP C 3 164 ? 178.915 154.977 108.180 1.00 78.17  ? 164 TRP L CE3 1 
ATOM   7077 C  CZ2 . TRP C 3 164 ? 179.886 152.749 106.732 1.00 78.17  ? 164 TRP L CZ2 1 
ATOM   7078 C  CZ3 . TRP C 3 164 ? 180.261 154.666 108.152 1.00 78.17  ? 164 TRP L CZ3 1 
ATOM   7079 C  CH2 . TRP C 3 164 ? 180.734 153.562 107.434 1.00 78.17  ? 164 TRP L CH2 1 
ATOM   7080 N  N   . THR C 3 165 ? 172.706 156.637 107.062 1.00 79.13  ? 165 THR L N   1 
ATOM   7081 C  CA  . THR C 3 165 ? 171.524 157.190 107.701 1.00 79.13  ? 165 THR L CA  1 
ATOM   7082 C  C   . THR C 3 165 ? 171.224 156.404 108.969 1.00 79.13  ? 165 THR L C   1 
ATOM   7083 O  O   . THR C 3 165 ? 171.446 155.192 109.029 1.00 79.13  ? 165 THR L O   1 
ATOM   7084 C  CB  . THR C 3 165 ? 170.337 157.136 106.739 1.00 79.13  ? 165 THR L CB  1 
ATOM   7085 O  OG1 . THR C 3 165 ? 170.732 157.698 105.485 1.00 79.13  ? 165 THR L OG1 1 
ATOM   7086 C  CG2 . THR C 3 165 ? 169.150 157.929 107.268 1.00 79.13  ? 165 THR L CG2 1 
ATOM   7087 N  N   . ASP C 3 166 ? 170.717 157.096 109.986 1.00 89.75  ? 166 ASP L N   1 
ATOM   7088 C  CA  . ASP C 3 166 ? 170.378 156.450 111.243 1.00 89.75  ? 166 ASP L CA  1 
ATOM   7089 C  C   . ASP C 3 166 ? 169.139 155.568 111.078 1.00 89.75  ? 166 ASP L C   1 
ATOM   7090 O  O   . ASP C 3 166 ? 168.587 155.405 109.986 1.00 89.75  ? 166 ASP L O   1 
ATOM   7091 C  CB  . ASP C 3 166 ? 170.159 157.496 112.333 1.00 89.75  ? 166 ASP L CB  1 
ATOM   7092 C  CG  . ASP C 3 166 ? 171.423 157.805 113.104 1.00 89.75  ? 166 ASP L CG  1 
ATOM   7093 O  OD1 . ASP C 3 166 ? 172.323 156.941 113.141 1.00 89.75  ? 166 ASP L OD1 1 
ATOM   7094 O  OD2 . ASP C 3 166 ? 171.515 158.910 113.677 1.00 89.75  ? 166 ASP L OD2 1 
ATOM   7095 N  N   . GLN C 3 167 ? 168.703 154.988 112.192 1.00 97.86  ? 167 GLN L N   1 
ATOM   7096 C  CA  . GLN C 3 167 ? 167.607 154.029 112.169 1.00 97.86  ? 167 GLN L CA  1 
ATOM   7097 C  C   . GLN C 3 167 ? 166.285 154.716 111.846 1.00 97.86  ? 167 GLN L C   1 
ATOM   7098 O  O   . GLN C 3 167 ? 165.891 155.680 112.509 1.00 97.86  ? 167 GLN L O   1 
ATOM   7099 C  CB  . GLN C 3 167 ? 167.534 153.319 113.518 1.00 97.86  ? 167 GLN L CB  1 
ATOM   7100 C  CG  . GLN C 3 167 ? 166.498 152.226 113.612 1.00 97.86  ? 167 GLN L CG  1 
ATOM   7101 C  CD  . GLN C 3 167 ? 166.817 151.065 112.698 1.00 97.86  ? 167 GLN L CD  1 
ATOM   7102 O  OE1 . GLN C 3 167 ? 167.970 150.686 112.537 1.00 97.86  ? 167 GLN L OE1 1 
ATOM   7103 N  NE2 . GLN C 3 167 ? 165.791 150.467 112.130 1.00 97.86  ? 167 GLN L NE2 1 
ATOM   7104 N  N   . ASP C 3 168 ? 165.601 154.217 110.819 1.00 98.77  ? 168 ASP L N   1 
ATOM   7105 C  CA  . ASP C 3 168 ? 164.325 154.785 110.408 1.00 98.77  ? 168 ASP L CA  1 
ATOM   7106 C  C   . ASP C 3 168 ? 163.202 154.322 111.326 1.00 98.77  ? 168 ASP L C   1 
ATOM   7107 O  O   . ASP C 3 168 ? 163.195 153.182 111.799 1.00 98.77  ? 168 ASP L O   1 
ATOM   7108 C  CB  . ASP C 3 168 ? 163.998 154.400 108.965 1.00 98.77  ? 168 ASP L CB  1 
ATOM   7109 C  CG  . ASP C 3 168 ? 164.886 155.097 107.958 1.00 98.77  ? 168 ASP L CG  1 
ATOM   7110 O  OD1 . ASP C 3 168 ? 165.352 156.218 108.249 1.00 98.77  ? 168 ASP L OD1 1 
ATOM   7111 O  OD2 . ASP C 3 168 ? 165.104 154.531 106.866 1.00 98.77  ? 168 ASP L OD2 1 
ATOM   7112 N  N   . SER C 3 169 ? 162.252 155.218 111.577 1.00 104.78 ? 169 SER L N   1 
ATOM   7113 C  CA  . SER C 3 169 ? 161.076 154.905 112.375 1.00 104.78 ? 169 SER L CA  1 
ATOM   7114 C  C   . SER C 3 169 ? 159.896 154.425 111.539 1.00 104.78 ? 169 SER L C   1 
ATOM   7115 O  O   . SER C 3 169 ? 158.868 154.044 112.108 1.00 104.78 ? 169 SER L O   1 
ATOM   7116 C  CB  . SER C 3 169 ? 160.658 156.129 113.197 1.00 104.78 ? 169 SER L CB  1 
ATOM   7117 N  N   . LYS C 3 170 ? 160.016 154.428 110.211 1.00 109.78 ? 170 LYS L N   1 
ATOM   7118 C  CA  . LYS C 3 170 ? 158.927 154.030 109.327 1.00 109.78 ? 170 LYS L CA  1 
ATOM   7119 C  C   . LYS C 3 170 ? 158.983 152.556 108.946 1.00 109.78 ? 170 LYS L C   1 
ATOM   7120 O  O   . LYS C 3 170 ? 158.053 151.802 109.246 1.00 109.78 ? 170 LYS L O   1 
ATOM   7121 C  CB  . LYS C 3 170 ? 158.940 154.891 108.058 1.00 109.78 ? 170 LYS L CB  1 
ATOM   7122 C  CG  . LYS C 3 170 ? 157.692 154.754 107.200 1.00 109.78 ? 170 LYS L CG  1 
ATOM   7123 C  CD  . LYS C 3 170 ? 157.745 155.676 105.993 1.00 109.78 ? 170 LYS L CD  1 
ATOM   7124 C  CE  . LYS C 3 170 ? 156.422 155.684 105.246 1.00 109.78 ? 170 LYS L CE  1 
ATOM   7125 N  NZ  . LYS C 3 170 ? 156.001 154.310 104.851 1.00 109.78 ? 170 LYS L NZ  1 
ATOM   7126 N  N   . ASP C 3 171 ? 160.063 152.128 108.290 1.00 105.01 ? 171 ASP L N   1 
ATOM   7127 C  CA  . ASP C 3 171 ? 160.211 150.745 107.866 1.00 105.01 ? 171 ASP L CA  1 
ATOM   7128 C  C   . ASP C 3 171 ? 161.441 150.068 108.451 1.00 105.01 ? 171 ASP L C   1 
ATOM   7129 O  O   . ASP C 3 171 ? 161.761 148.948 108.036 1.00 105.01 ? 171 ASP L O   1 
ATOM   7130 C  CB  . ASP C 3 171 ? 160.257 150.656 106.334 1.00 105.01 ? 171 ASP L CB  1 
ATOM   7131 C  CG  . ASP C 3 171 ? 161.145 151.714 105.718 1.00 105.01 ? 171 ASP L CG  1 
ATOM   7132 O  OD1 . ASP C 3 171 ? 161.591 152.618 106.456 1.00 105.01 ? 171 ASP L OD1 1 
ATOM   7133 O  OD2 . ASP C 3 171 ? 161.390 151.648 104.496 1.00 105.01 ? 171 ASP L OD2 1 
ATOM   7134 N  N   . SER C 3 172 ? 162.129 150.717 109.395 1.00 97.68  ? 172 SER L N   1 
ATOM   7135 C  CA  . SER C 3 172 ? 163.258 150.158 110.143 1.00 97.68  ? 172 SER L CA  1 
ATOM   7136 C  C   . SER C 3 172 ? 164.389 149.685 109.224 1.00 97.68  ? 172 SER L C   1 
ATOM   7137 O  O   . SER C 3 172 ? 164.743 148.506 109.182 1.00 97.68  ? 172 SER L O   1 
ATOM   7138 C  CB  . SER C 3 172 ? 162.796 149.028 111.071 1.00 97.68  ? 172 SER L CB  1 
ATOM   7139 O  OG  . SER C 3 172 ? 163.763 148.771 112.073 1.00 97.68  ? 172 SER L OG  1 
ATOM   7140 N  N   . THR C 3 173 ? 164.967 150.637 108.495 1.00 92.21  ? 173 THR L N   1 
ATOM   7141 C  CA  . THR C 3 173 ? 166.039 150.336 107.558 1.00 92.21  ? 173 THR L CA  1 
ATOM   7142 C  C   . THR C 3 173 ? 167.035 151.487 107.537 1.00 92.21  ? 173 THR L C   1 
ATOM   7143 O  O   . THR C 3 173 ? 166.820 152.538 108.145 1.00 92.21  ? 173 THR L O   1 
ATOM   7144 C  CB  . THR C 3 173 ? 165.498 150.076 106.148 1.00 92.21  ? 173 THR L CB  1 
ATOM   7145 O  OG1 . THR C 3 173 ? 166.575 149.681 105.289 1.00 92.21  ? 173 THR L OG1 1 
ATOM   7146 C  CG2 . THR C 3 173 ? 164.842 151.328 105.593 1.00 92.21  ? 173 THR L CG2 1 
ATOM   7147 N  N   . TYR C 3 174 ? 168.144 151.270 106.832 1.00 89.23  ? 174 TYR L N   1 
ATOM   7148 C  CA  . TYR C 3 174 ? 169.209 152.250 106.706 1.00 89.23  ? 174 TYR L CA  1 
ATOM   7149 C  C   . TYR C 3 174 ? 169.193 152.871 105.311 1.00 89.23  ? 174 TYR L C   1 
ATOM   7150 O  O   . TYR C 3 174 ? 168.339 152.570 104.474 1.00 89.23  ? 174 TYR L O   1 
ATOM   7151 C  CB  . TYR C 3 174 ? 170.566 151.606 106.989 1.00 89.23  ? 174 TYR L CB  1 
ATOM   7152 C  CG  . TYR C 3 174 ? 170.725 151.076 108.392 1.00 89.23  ? 174 TYR L CG  1 
ATOM   7153 C  CD1 . TYR C 3 174 ? 170.731 151.933 109.484 1.00 89.23  ? 174 TYR L CD1 1 
ATOM   7154 C  CD2 . TYR C 3 174 ? 170.882 149.718 108.624 1.00 89.23  ? 174 TYR L CD2 1 
ATOM   7155 C  CE1 . TYR C 3 174 ? 170.881 151.449 110.768 1.00 89.23  ? 174 TYR L CE1 1 
ATOM   7156 C  CE2 . TYR C 3 174 ? 171.034 149.226 109.902 1.00 89.23  ? 174 TYR L CE2 1 
ATOM   7157 C  CZ  . TYR C 3 174 ? 171.032 150.095 110.968 1.00 89.23  ? 174 TYR L CZ  1 
ATOM   7158 O  OH  . TYR C 3 174 ? 171.186 149.600 112.239 1.00 89.23  ? 174 TYR L OH  1 
ATOM   7159 N  N   . SER C 3 175 ? 170.162 153.752 105.062 1.00 80.68  ? 175 SER L N   1 
ATOM   7160 C  CA  . SER C 3 175 ? 170.356 154.344 103.742 1.00 80.68  ? 175 SER L CA  1 
ATOM   7161 C  C   . SER C 3 175 ? 171.799 154.813 103.635 1.00 80.68  ? 175 SER L C   1 
ATOM   7162 O  O   . SER C 3 175 ? 172.292 155.512 104.524 1.00 80.68  ? 175 SER L O   1 
ATOM   7163 C  CB  . SER C 3 175 ? 169.391 155.503 103.499 1.00 80.68  ? 175 SER L CB  1 
ATOM   7164 O  OG  . SER C 3 175 ? 169.594 156.062 102.215 1.00 80.68  ? 175 SER L OG  1 
ATOM   7165 N  N   . MET C 3 176 ? 172.466 154.430 102.550 1.00 82.04  ? 176 MET L N   1 
ATOM   7166 C  CA  . MET C 3 176 ? 173.888 154.675 102.352 1.00 82.04  ? 176 MET L CA  1 
ATOM   7167 C  C   . MET C 3 176 ? 174.089 155.549 101.121 1.00 82.04  ? 176 MET L C   1 
ATOM   7168 O  O   . MET C 3 176 ? 173.493 155.292 100.072 1.00 82.04  ? 176 MET L O   1 
ATOM   7169 C  CB  . MET C 3 176 ? 174.633 153.346 102.199 1.00 82.04  ? 176 MET L CB  1 
ATOM   7170 C  CG  . MET C 3 176 ? 176.066 153.438 101.706 1.00 82.04  ? 176 MET L CG  1 
ATOM   7171 S  SD  . MET C 3 176 ? 177.225 154.103 102.910 1.00 82.04  ? 176 MET L SD  1 
ATOM   7172 C  CE  . MET C 3 176 ? 178.620 154.462 101.844 1.00 82.04  ? 176 MET L CE  1 
ATOM   7173 N  N   . SER C 3 177 ? 174.919 156.579 101.248 1.00 86.31  ? 177 SER L N   1 
ATOM   7174 C  CA  . SER C 3 177 ? 175.234 157.466 100.137 1.00 86.31  ? 177 SER L CA  1 
ATOM   7175 C  C   . SER C 3 177 ? 176.739 157.525 99.933  1.00 86.31  ? 177 SER L C   1 
ATOM   7176 O  O   . SER C 3 177 ? 177.494 157.756 100.882 1.00 86.31  ? 177 SER L O   1 
ATOM   7177 C  CB  . SER C 3 177 ? 174.696 158.872 100.379 1.00 86.31  ? 177 SER L CB  1 
ATOM   7178 O  OG  . SER C 3 177 ? 175.070 159.737 99.323  1.00 86.31  ? 177 SER L OG  1 
ATOM   7179 N  N   . SER C 3 178 ? 177.170 157.329 98.689  1.00 98.83  ? 178 SER L N   1 
ATOM   7180 C  CA  . SER C 3 178 ? 178.589 157.329 98.358  1.00 98.83  ? 178 SER L CA  1 
ATOM   7181 C  C   . SER C 3 178 ? 178.818 158.204 97.137  1.00 98.83  ? 178 SER L C   1 
ATOM   7182 O  O   . SER C 3 178 ? 178.079 158.107 96.153  1.00 98.83  ? 178 SER L O   1 
ATOM   7183 C  CB  . SER C 3 178 ? 179.100 155.907 98.098  1.00 98.83  ? 178 SER L CB  1 
ATOM   7184 O  OG  . SER C 3 178 ? 180.517 155.869 98.063  1.00 98.83  ? 178 SER L OG  1 
ATOM   7185 N  N   . THR C 3 179 ? 179.845 159.048 97.204  1.00 107.01 ? 179 THR L N   1 
ATOM   7186 C  CA  . THR C 3 179 ? 180.176 159.984 96.139  1.00 107.01 ? 179 THR L CA  1 
ATOM   7187 C  C   . THR C 3 179 ? 181.648 159.839 95.785  1.00 107.01 ? 179 THR L C   1 
ATOM   7188 O  O   . THR C 3 179 ? 182.507 159.850 96.673  1.00 107.01 ? 179 THR L O   1 
ATOM   7189 C  CB  . THR C 3 179 ? 179.881 161.428 96.560  1.00 107.01 ? 179 THR L CB  1 
ATOM   7190 O  OG1 . THR C 3 179 ? 178.536 161.523 97.045  1.00 107.01 ? 179 THR L OG1 1 
ATOM   7191 C  CG2 . THR C 3 179 ? 180.058 162.376 95.385  1.00 107.01 ? 179 THR L CG2 1 
ATOM   7192 N  N   . LEU C 3 180 ? 181.936 159.709 94.494  1.00 118.58 ? 180 LEU L N   1 
ATOM   7193 C  CA  . LEU C 3 180 ? 183.305 159.639 94.001  1.00 118.58 ? 180 LEU L CA  1 
ATOM   7194 C  C   . LEU C 3 180 ? 183.786 161.049 93.691  1.00 118.58 ? 180 LEU L C   1 
ATOM   7195 O  O   . LEU C 3 180 ? 183.184 161.748 92.868  1.00 118.58 ? 180 LEU L O   1 
ATOM   7196 C  CB  . LEU C 3 180 ? 183.399 158.752 92.760  1.00 118.58 ? 180 LEU L CB  1 
ATOM   7197 C  CG  . LEU C 3 180 ? 184.794 158.224 92.418  1.00 118.58 ? 180 LEU L CG  1 
ATOM   7198 C  CD1 . LEU C 3 180 ? 185.287 157.264 93.488  1.00 118.58 ? 180 LEU L CD1 1 
ATOM   7199 C  CD2 . LEU C 3 180 ? 184.793 157.553 91.054  1.00 118.58 ? 180 LEU L CD2 1 
ATOM   7200 N  N   . THR C 3 181 ? 184.863 161.464 94.350  1.00 129.15 ? 181 THR L N   1 
ATOM   7201 C  CA  . THR C 3 181 ? 185.440 162.788 94.162  1.00 129.15 ? 181 THR L CA  1 
ATOM   7202 C  C   . THR C 3 181 ? 186.630 162.679 93.217  1.00 129.15 ? 181 THR L C   1 
ATOM   7203 O  O   . THR C 3 181 ? 187.632 162.034 93.546  1.00 129.15 ? 181 THR L O   1 
ATOM   7204 C  CB  . THR C 3 181 ? 185.870 163.396 95.497  1.00 129.15 ? 181 THR L CB  1 
ATOM   7205 O  OG1 . THR C 3 181 ? 186.777 162.508 96.159  1.00 129.15 ? 181 THR L OG1 1 
ATOM   7206 C  CG2 . THR C 3 181 ? 184.660 163.632 96.388  1.00 129.15 ? 181 THR L CG2 1 
ATOM   7207 N  N   . LEU C 3 182 ? 186.516 163.308 92.050  1.00 136.47 ? 182 LEU L N   1 
ATOM   7208 C  CA  . LEU C 3 182 ? 187.564 163.285 91.039  1.00 136.47 ? 182 LEU L CA  1 
ATOM   7209 C  C   . LEU C 3 182 ? 187.557 164.629 90.318  1.00 136.47 ? 182 LEU L C   1 
ATOM   7210 O  O   . LEU C 3 182 ? 186.842 165.560 90.702  1.00 136.47 ? 182 LEU L O   1 
ATOM   7211 C  CB  . LEU C 3 182 ? 187.365 162.100 90.084  1.00 136.47 ? 182 LEU L CB  1 
ATOM   7212 C  CG  . LEU C 3 182 ? 188.043 160.783 90.471  1.00 136.47 ? 182 LEU L CG  1 
ATOM   7213 C  CD1 . LEU C 3 182 ? 187.979 159.788 89.323  1.00 136.47 ? 182 LEU L CD1 1 
ATOM   7214 C  CD2 . LEU C 3 182 ? 189.486 161.029 90.888  1.00 136.47 ? 182 LEU L CD2 1 
ATOM   7215 N  N   . THR C 3 183 ? 188.358 164.731 89.262  1.00 139.84 ? 183 THR L N   1 
ATOM   7216 C  CA  . THR C 3 183 ? 188.487 165.955 88.488  1.00 139.84 ? 183 THR L CA  1 
ATOM   7217 C  C   . THR C 3 183 ? 187.853 165.781 87.114  1.00 139.84 ? 183 THR L C   1 
ATOM   7218 O  O   . THR C 3 183 ? 187.653 164.662 86.633  1.00 139.84 ? 183 THR L O   1 
ATOM   7219 C  CB  . THR C 3 183 ? 189.958 166.360 88.336  1.00 139.84 ? 183 THR L CB  1 
ATOM   7220 O  OG1 . THR C 3 183 ? 190.628 165.422 87.486  1.00 139.84 ? 183 THR L OG1 1 
ATOM   7221 C  CG2 . THR C 3 183 ? 190.645 166.386 89.693  1.00 139.84 ? 183 THR L CG2 1 
ATOM   7222 N  N   . LYS C 3 184 ? 187.532 166.917 86.487  1.00 140.78 ? 184 LYS L N   1 
ATOM   7223 C  CA  . LYS C 3 184 ? 186.927 166.892 85.159  1.00 140.78 ? 184 LYS L CA  1 
ATOM   7224 C  C   . LYS C 3 184 ? 187.897 166.369 84.107  1.00 140.78 ? 184 LYS L C   1 
ATOM   7225 O  O   . LYS C 3 184 ? 187.467 165.758 83.121  1.00 140.78 ? 184 LYS L O   1 
ATOM   7226 C  CB  . LYS C 3 184 ? 186.433 168.287 84.778  1.00 140.78 ? 184 LYS L CB  1 
ATOM   7227 N  N   . ASP C 3 185 ? 189.197 166.614 84.287  1.00 144.57 ? 185 ASP L N   1 
ATOM   7228 C  CA  . ASP C 3 185 ? 190.194 166.024 83.398  1.00 144.57 ? 185 ASP L CA  1 
ATOM   7229 C  C   . ASP C 3 185 ? 190.230 164.509 83.545  1.00 144.57 ? 185 ASP L C   1 
ATOM   7230 O  O   . ASP C 3 185 ? 190.374 163.785 82.553  1.00 144.57 ? 185 ASP L O   1 
ATOM   7231 C  CB  . ASP C 3 185 ? 191.570 166.625 83.681  1.00 144.57 ? 185 ASP L CB  1 
ATOM   7232 C  CG  . ASP C 3 185 ? 191.642 168.101 83.348  1.00 144.57 ? 185 ASP L CG  1 
ATOM   7233 O  OD1 . ASP C 3 185 ? 190.891 168.546 82.455  1.00 144.57 ? 185 ASP L OD1 1 
ATOM   7234 O  OD2 . ASP C 3 185 ? 192.447 168.816 83.980  1.00 144.57 ? 185 ASP L OD2 1 
ATOM   7235 N  N   . GLU C 3 186 ? 190.104 164.012 84.777  1.00 145.78 ? 186 GLU L N   1 
ATOM   7236 C  CA  . GLU C 3 186 ? 190.038 162.575 85.004  1.00 145.78 ? 186 GLU L CA  1 
ATOM   7237 C  C   . GLU C 3 186 ? 188.689 162.003 84.583  1.00 145.78 ? 186 GLU L C   1 
ATOM   7238 O  O   . GLU C 3 186 ? 188.604 160.812 84.260  1.00 145.78 ? 186 GLU L O   1 
ATOM   7239 C  CB  . GLU C 3 186 ? 190.325 162.276 86.480  1.00 145.78 ? 186 GLU L CB  1 
ATOM   7240 C  CG  . GLU C 3 186 ? 190.520 160.806 86.829  1.00 145.78 ? 186 GLU L CG  1 
ATOM   7241 C  CD  . GLU C 3 186 ? 191.801 160.230 86.253  1.00 145.78 ? 186 GLU L CD  1 
ATOM   7242 O  OE1 . GLU C 3 186 ? 192.762 161.000 86.042  1.00 145.78 ? 186 GLU L OE1 1 
ATOM   7243 O  OE2 . GLU C 3 186 ? 191.847 159.005 86.012  1.00 145.78 ? 186 GLU L OE2 1 
ATOM   7244 N  N   . TYR C 3 187 ? 187.640 162.832 84.574  1.00 140.83 ? 187 TYR L N   1 
ATOM   7245 C  CA  . TYR C 3 187 ? 186.333 162.401 84.084  1.00 140.83 ? 187 TYR L CA  1 
ATOM   7246 C  C   . TYR C 3 187 ? 186.387 162.044 82.603  1.00 140.83 ? 187 TYR L C   1 
ATOM   7247 O  O   . TYR C 3 187 ? 185.801 161.041 82.179  1.00 140.83 ? 187 TYR L O   1 
ATOM   7248 C  CB  . TYR C 3 187 ? 185.299 163.501 84.346  1.00 140.83 ? 187 TYR L CB  1 
ATOM   7249 C  CG  . TYR C 3 187 ? 183.848 163.103 84.153  1.00 140.83 ? 187 TYR L CG  1 
ATOM   7250 C  CD1 . TYR C 3 187 ? 183.271 163.070 82.886  1.00 140.83 ? 187 TYR L CD1 1 
ATOM   7251 C  CD2 . TYR C 3 187 ? 183.054 162.766 85.240  1.00 140.83 ? 187 TYR L CD2 1 
ATOM   7252 C  CE1 . TYR C 3 187 ? 181.949 162.709 82.711  1.00 140.83 ? 187 TYR L CE1 1 
ATOM   7253 C  CE2 . TYR C 3 187 ? 181.729 162.404 85.073  1.00 140.83 ? 187 TYR L CE2 1 
ATOM   7254 C  CZ  . TYR C 3 187 ? 181.184 162.377 83.807  1.00 140.83 ? 187 TYR L CZ  1 
ATOM   7255 O  OH  . TYR C 3 187 ? 179.867 162.018 83.634  1.00 140.83 ? 187 TYR L OH  1 
ATOM   7256 N  N   . GLU C 3 188 ? 187.083 162.849 81.801  1.00 142.60 ? 188 GLU L N   1 
ATOM   7257 C  CA  . GLU C 3 188 ? 187.179 162.584 80.373  1.00 142.60 ? 188 GLU L CA  1 
ATOM   7258 C  C   . GLU C 3 188 ? 188.149 161.458 80.043  1.00 142.60 ? 188 GLU L C   1 
ATOM   7259 O  O   . GLU C 3 188 ? 188.127 160.956 78.914  1.00 142.60 ? 188 GLU L O   1 
ATOM   7260 C  CB  . GLU C 3 188 ? 187.596 163.856 79.632  1.00 142.60 ? 188 GLU L CB  1 
ATOM   7261 C  CG  . GLU C 3 188 ? 186.431 164.750 79.233  1.00 142.60 ? 188 GLU L CG  1 
ATOM   7262 C  CD  . GLU C 3 188 ? 185.207 163.963 78.806  1.00 142.60 ? 188 GLU L CD  1 
ATOM   7263 O  OE1 . GLU C 3 188 ? 185.236 163.366 77.709  1.00 142.60 ? 188 GLU L OE1 1 
ATOM   7264 O  OE2 . GLU C 3 188 ? 184.214 163.946 79.565  1.00 142.60 ? 188 GLU L OE2 1 
ATOM   7265 N  N   . ARG C 3 189 ? 188.990 161.051 80.991  1.00 143.08 ? 189 ARG L N   1 
ATOM   7266 C  CA  . ARG C 3 189 ? 189.938 159.965 80.788  1.00 143.08 ? 189 ARG L CA  1 
ATOM   7267 C  C   . ARG C 3 189 ? 189.390 158.611 81.220  1.00 143.08 ? 189 ARG L C   1 
ATOM   7268 O  O   . ARG C 3 189 ? 190.127 157.620 81.183  1.00 143.08 ? 189 ARG L O   1 
ATOM   7269 C  CB  . ARG C 3 189 ? 191.242 160.255 81.540  1.00 143.08 ? 189 ARG L CB  1 
ATOM   7270 N  N   . HIS C 3 190 ? 188.125 158.545 81.626  1.00 143.37 ? 190 HIS L N   1 
ATOM   7271 C  CA  . HIS C 3 190 ? 187.510 157.301 82.061  1.00 143.37 ? 190 HIS L CA  1 
ATOM   7272 C  C   . HIS C 3 190 ? 186.162 157.152 81.373  1.00 143.37 ? 190 HIS L C   1 
ATOM   7273 O  O   . HIS C 3 190 ? 185.532 158.142 80.991  1.00 143.37 ? 190 HIS L O   1 
ATOM   7274 C  CB  . HIS C 3 190 ? 187.336 157.265 83.585  1.00 143.37 ? 190 HIS L CB  1 
ATOM   7275 C  CG  . HIS C 3 190 ? 188.546 156.780 84.320  1.00 143.37 ? 190 HIS L CG  1 
ATOM   7276 N  ND1 . HIS C 3 190 ? 189.276 155.683 83.914  1.00 143.37 ? 190 HIS L ND1 1 
ATOM   7277 C  CD2 . HIS C 3 190 ? 189.155 157.244 85.437  1.00 143.37 ? 190 HIS L CD2 1 
ATOM   7278 C  CE1 . HIS C 3 190 ? 190.281 155.492 84.750  1.00 143.37 ? 190 HIS L CE1 1 
ATOM   7279 N  NE2 . HIS C 3 190 ? 190.231 156.425 85.683  1.00 143.37 ? 190 HIS L NE2 1 
ATOM   7280 N  N   . ASN C 3 191 ? 185.721 155.902 81.215  1.00 134.20 ? 191 ASN L N   1 
ATOM   7281 C  CA  . ASN C 3 191 ? 184.467 155.616 80.532  1.00 134.20 ? 191 ASN L CA  1 
ATOM   7282 C  C   . ASN C 3 191 ? 183.540 154.678 81.289  1.00 134.20 ? 191 ASN L C   1 
ATOM   7283 O  O   . ASN C 3 191 ? 182.331 154.703 81.031  1.00 134.20 ? 191 ASN L O   1 
ATOM   7284 C  CB  . ASN C 3 191 ? 184.737 155.020 79.141  1.00 134.20 ? 191 ASN L CB  1 
ATOM   7285 N  N   . SER C 3 192 ? 184.050 153.862 82.206  1.00 134.88 ? 192 SER L N   1 
ATOM   7286 C  CA  . SER C 3 192 ? 183.231 152.927 82.967  1.00 134.88 ? 192 SER L CA  1 
ATOM   7287 C  C   . SER C 3 192 ? 183.054 153.460 84.382  1.00 134.88 ? 192 SER L C   1 
ATOM   7288 O  O   . SER C 3 192 ? 184.038 153.785 85.055  1.00 134.88 ? 192 SER L O   1 
ATOM   7289 C  CB  . SER C 3 192 ? 183.868 151.537 82.989  1.00 134.88 ? 192 SER L CB  1 
ATOM   7290 N  N   . TYR C 3 193 ? 181.803 153.552 84.828  1.00 134.51 ? 193 TYR L N   1 
ATOM   7291 C  CA  . TYR C 3 193 ? 181.484 154.026 86.171  1.00 134.51 ? 193 TYR L CA  1 
ATOM   7292 C  C   . TYR C 3 193 ? 180.486 153.055 86.784  1.00 134.51 ? 193 TYR L C   1 
ATOM   7293 O  O   . TYR C 3 193 ? 179.308 153.059 86.412  1.00 134.51 ? 193 TYR L O   1 
ATOM   7294 C  CB  . TYR C 3 193 ? 180.916 155.444 86.141  1.00 134.51 ? 193 TYR L CB  1 
ATOM   7295 C  CG  . TYR C 3 193 ? 181.954 156.510 85.889  1.00 134.51 ? 193 TYR L CG  1 
ATOM   7296 C  CD1 . TYR C 3 193 ? 183.153 156.514 86.588  1.00 134.51 ? 193 TYR L CD1 1 
ATOM   7297 C  CD2 . TYR C 3 193 ? 181.733 157.515 84.956  1.00 134.51 ? 193 TYR L CD2 1 
ATOM   7298 C  CE1 . TYR C 3 193 ? 184.107 157.485 86.363  1.00 134.51 ? 193 TYR L CE1 1 
ATOM   7299 C  CE2 . TYR C 3 193 ? 182.679 158.492 84.724  1.00 134.51 ? 193 TYR L CE2 1 
ATOM   7300 C  CZ  . TYR C 3 193 ? 183.865 158.472 85.431  1.00 134.51 ? 193 TYR L CZ  1 
ATOM   7301 O  OH  . TYR C 3 193 ? 184.815 159.442 85.206  1.00 134.51 ? 193 TYR L OH  1 
ATOM   7302 N  N   . THR C 3 194 ? 180.951 152.231 87.718  1.00 130.72 ? 194 THR L N   1 
ATOM   7303 C  CA  . THR C 3 194 ? 180.105 151.223 88.337  1.00 130.72 ? 194 THR L CA  1 
ATOM   7304 C  C   . THR C 3 194 ? 180.278 151.267 89.846  1.00 130.72 ? 194 THR L C   1 
ATOM   7305 O  O   . THR C 3 194 ? 181.403 151.341 90.349  1.00 130.72 ? 194 THR L O   1 
ATOM   7306 C  CB  . THR C 3 194 ? 180.436 149.816 87.816  1.00 130.72 ? 194 THR L CB  1 
ATOM   7307 O  OG1 . THR C 3 194 ? 180.568 149.850 86.390  1.00 130.72 ? 194 THR L OG1 1 
ATOM   7308 C  CG2 . THR C 3 194 ? 179.339 148.829 88.193  1.00 130.72 ? 194 THR L CG2 1 
ATOM   7309 N  N   . CYS C 3 195 ? 179.158 151.226 90.561  1.00 122.86 ? 195 CYS L N   1 
ATOM   7310 C  CA  . CYS C 3 195 ? 179.147 151.097 92.010  1.00 122.86 ? 195 CYS L CA  1 
ATOM   7311 C  C   . CYS C 3 195 ? 178.415 149.818 92.388  1.00 122.86 ? 195 CYS L C   1 
ATOM   7312 O  O   . CYS C 3 195 ? 177.346 149.519 91.846  1.00 122.86 ? 195 CYS L O   1 
ATOM   7313 C  CB  . CYS C 3 195 ? 178.492 152.314 92.677  1.00 122.86 ? 195 CYS L CB  1 
ATOM   7314 S  SG  . CYS C 3 195 ? 176.798 152.679 92.152  1.00 122.86 ? 195 CYS L SG  1 
ATOM   7315 N  N   . GLU C 3 196 ? 179.005 149.055 93.304  1.00 123.93 ? 196 GLU L N   1 
ATOM   7316 C  CA  . GLU C 3 196 ? 178.436 147.777 93.703  1.00 123.93 ? 196 GLU L CA  1 
ATOM   7317 C  C   . GLU C 3 196 ? 178.645 147.579 95.196  1.00 123.93 ? 196 GLU L C   1 
ATOM   7318 O  O   . GLU C 3 196 ? 179.557 148.150 95.800  1.00 123.93 ? 196 GLU L O   1 
ATOM   7319 C  CB  . GLU C 3 196 ? 179.048 146.619 92.902  1.00 123.93 ? 196 GLU L CB  1 
ATOM   7320 C  CG  . GLU C 3 196 ? 180.448 146.218 93.336  1.00 123.93 ? 196 GLU L CG  1 
ATOM   7321 C  CD  . GLU C 3 196 ? 180.958 144.996 92.600  1.00 123.93 ? 196 GLU L CD  1 
ATOM   7322 O  OE1 . GLU C 3 196 ? 180.752 144.912 91.371  1.00 123.93 ? 196 GLU L OE1 1 
ATOM   7323 O  OE2 . GLU C 3 196 ? 181.566 144.119 93.249  1.00 123.93 ? 196 GLU L OE2 1 
ATOM   7324 N  N   . ALA C 3 197 ? 177.775 146.764 95.789  1.00 118.06 ? 197 ALA L N   1 
ATOM   7325 C  CA  . ALA C 3 197 ? 177.825 146.498 97.218  1.00 118.06 ? 197 ALA L CA  1 
ATOM   7326 C  C   . ALA C 3 197 ? 177.386 145.065 97.473  1.00 118.06 ? 197 ALA L C   1 
ATOM   7327 O  O   . ALA C 3 197 ? 176.429 144.584 96.861  1.00 118.06 ? 197 ALA L O   1 
ATOM   7328 C  CB  . ALA C 3 197 ? 176.939 147.471 98.001  1.00 118.06 ? 197 ALA L CB  1 
ATOM   7329 N  N   . THR C 3 198 ? 178.086 144.395 98.383  1.00 112.57 ? 198 THR L N   1 
ATOM   7330 C  CA  . THR C 3 198 ? 177.807 142.997 98.705  1.00 112.57 ? 198 THR L CA  1 
ATOM   7331 C  C   . THR C 3 198 ? 176.808 142.957 99.855  1.00 112.57 ? 198 THR L C   1 
ATOM   7332 O  O   . THR C 3 198 ? 177.179 143.088 101.023 1.00 112.57 ? 198 THR L O   1 
ATOM   7333 C  CB  . THR C 3 198 ? 179.091 142.255 99.058  1.00 112.57 ? 198 THR L CB  1 
ATOM   7334 O  OG1 . THR C 3 198 ? 180.040 142.408 97.995  1.00 112.57 ? 198 THR L OG1 1 
ATOM   7335 C  CG2 . THR C 3 198 ? 178.809 140.773 99.264  1.00 112.57 ? 198 THR L CG2 1 
ATOM   7336 N  N   . HIS C 3 199 ? 175.535 142.779 99.521  1.00 104.11 ? 199 HIS L N   1 
ATOM   7337 C  CA  . HIS C 3 199 ? 174.497 142.587 100.519 1.00 104.11 ? 199 HIS L CA  1 
ATOM   7338 C  C   . HIS C 3 199 ? 174.426 141.114 100.918 1.00 104.11 ? 199 HIS L C   1 
ATOM   7339 O  O   . HIS C 3 199 ? 174.916 140.229 100.217 1.00 104.11 ? 199 HIS L O   1 
ATOM   7340 C  CB  . HIS C 3 199 ? 173.150 143.078 99.989  1.00 104.11 ? 199 HIS L CB  1 
ATOM   7341 C  CG  . HIS C 3 199 ? 172.147 143.364 101.062 1.00 104.11 ? 199 HIS L CG  1 
ATOM   7342 N  ND1 . HIS C 3 199 ? 170.953 142.684 101.164 1.00 104.11 ? 199 HIS L ND1 1 
ATOM   7343 C  CD2 . HIS C 3 199 ? 172.165 144.247 102.088 1.00 104.11 ? 199 HIS L CD2 1 
ATOM   7344 C  CE1 . HIS C 3 199 ? 170.275 143.142 102.200 1.00 104.11 ? 199 HIS L CE1 1 
ATOM   7345 N  NE2 . HIS C 3 199 ? 170.988 144.091 102.779 1.00 104.11 ? 199 HIS L NE2 1 
ATOM   7346 N  N   . LYS C 3 200 ? 173.814 140.855 102.071 1.00 106.02 ? 200 LYS L N   1 
ATOM   7347 C  CA  . LYS C 3 200 ? 173.737 139.497 102.589 1.00 106.02 ? 200 LYS L CA  1 
ATOM   7348 C  C   . LYS C 3 200 ? 172.571 138.700 102.021 1.00 106.02 ? 200 LYS L C   1 
ATOM   7349 O  O   . LYS C 3 200 ? 172.457 137.506 102.320 1.00 106.02 ? 200 LYS L O   1 
ATOM   7350 C  CB  . LYS C 3 200 ? 173.655 139.520 104.118 1.00 106.02 ? 200 LYS L CB  1 
ATOM   7351 C  CG  . LYS C 3 200 ? 174.901 140.089 104.778 1.00 106.02 ? 200 LYS L CG  1 
ATOM   7352 C  CD  . LYS C 3 200 ? 174.610 140.624 106.168 1.00 106.02 ? 200 LYS L CD  1 
ATOM   7353 C  CE  . LYS C 3 200 ? 175.792 140.398 107.097 1.00 106.02 ? 200 LYS L CE  1 
ATOM   7354 N  NZ  . LYS C 3 200 ? 175.624 141.108 108.395 1.00 106.02 ? 200 LYS L NZ  1 
ATOM   7355 N  N   . THR C 3 201 ? 171.705 139.320 101.218 1.00 109.78 ? 201 THR L N   1 
ATOM   7356 C  CA  . THR C 3 201 ? 170.635 138.566 100.572 1.00 109.78 ? 201 THR L CA  1 
ATOM   7357 C  C   . THR C 3 201 ? 171.164 137.724 99.418  1.00 109.78 ? 201 THR L C   1 
ATOM   7358 O  O   . THR C 3 201 ? 170.744 136.575 99.237  1.00 109.78 ? 201 THR L O   1 
ATOM   7359 C  CB  . THR C 3 201 ? 169.538 139.513 100.085 1.00 109.78 ? 201 THR L CB  1 
ATOM   7360 O  OG1 . THR C 3 201 ? 170.124 140.580 99.327  1.00 109.78 ? 201 THR L OG1 1 
ATOM   7361 C  CG2 . THR C 3 201 ? 168.759 140.081 101.261 1.00 109.78 ? 201 THR L CG2 1 
ATOM   7362 N  N   . SER C 3 202 ? 172.082 138.274 98.626  1.00 120.77 ? 202 SER L N   1 
ATOM   7363 C  CA  . SER C 3 202 ? 172.643 137.583 97.473  1.00 120.77 ? 202 SER L CA  1 
ATOM   7364 C  C   . SER C 3 202 ? 174.157 137.549 97.599  1.00 120.77 ? 202 SER L C   1 
ATOM   7365 O  O   . SER C 3 202 ? 174.776 138.568 97.922  1.00 120.77 ? 202 SER L O   1 
ATOM   7366 C  CB  . SER C 3 202 ? 172.235 138.267 96.165  1.00 120.77 ? 202 SER L CB  1 
ATOM   7367 O  OG  . SER C 3 202 ? 172.837 137.635 95.049  1.00 120.77 ? 202 SER L OG  1 
ATOM   7368 N  N   . THR C 3 203 ? 174.747 136.375 97.350  1.00 126.33 ? 203 THR L N   1 
ATOM   7369 C  CA  . THR C 3 203 ? 176.200 136.240 97.419  1.00 126.33 ? 203 THR L CA  1 
ATOM   7370 C  C   . THR C 3 203 ? 176.887 137.088 96.355  1.00 126.33 ? 203 THR L C   1 
ATOM   7371 O  O   . THR C 3 203 ? 177.922 137.711 96.619  1.00 126.33 ? 203 THR L O   1 
ATOM   7372 C  CB  . THR C 3 203 ? 176.602 134.772 97.275  1.00 126.33 ? 203 THR L CB  1 
ATOM   7373 O  OG1 . THR C 3 203 ? 175.879 134.181 96.188  1.00 126.33 ? 203 THR L OG1 1 
ATOM   7374 C  CG2 . THR C 3 203 ? 176.297 134.009 98.556  1.00 126.33 ? 203 THR L CG2 1 
ATOM   7375 N  N   . SER C 3 204 ? 176.331 137.119 95.152  1.00 125.26 ? 204 SER L N   1 
ATOM   7376 C  CA  . SER C 3 204 ? 176.825 138.033 94.132  1.00 125.26 ? 204 SER L CA  1 
ATOM   7377 C  C   . SER C 3 204 ? 176.397 139.454 94.481  1.00 125.26 ? 204 SER L C   1 
ATOM   7378 O  O   . SER C 3 204 ? 175.210 139.690 94.740  1.00 125.26 ? 204 SER L O   1 
ATOM   7379 C  CB  . SER C 3 204 ? 176.294 137.643 92.755  1.00 125.26 ? 204 SER L CB  1 
ATOM   7380 O  OG  . SER C 3 204 ? 174.882 137.756 92.704  1.00 125.26 ? 204 SER L OG  1 
ATOM   7381 N  N   . PRO C 3 205 ? 177.322 140.413 94.526  1.00 124.38 ? 205 PRO L N   1 
ATOM   7382 C  CA  . PRO C 3 205 ? 176.940 141.789 94.859  1.00 124.38 ? 205 PRO L CA  1 
ATOM   7383 C  C   . PRO C 3 205 ? 176.095 142.426 93.768  1.00 124.38 ? 205 PRO L C   1 
ATOM   7384 O  O   . PRO C 3 205 ? 176.283 142.177 92.574  1.00 124.38 ? 205 PRO L O   1 
ATOM   7385 C  CB  . PRO C 3 205 ? 178.288 142.504 95.006  1.00 124.38 ? 205 PRO L CB  1 
ATOM   7386 C  CG  . PRO C 3 205 ? 179.225 141.712 94.162  1.00 124.38 ? 205 PRO L CG  1 
ATOM   7387 C  CD  . PRO C 3 205 ? 178.765 140.284 94.262  1.00 124.38 ? 205 PRO L CD  1 
ATOM   7388 N  N   . ILE C 3 206 ? 175.152 143.260 94.198  1.00 126.48 ? 206 ILE L N   1 
ATOM   7389 C  CA  . ILE C 3 206 ? 174.275 143.968 93.273  1.00 126.48 ? 206 ILE L CA  1 
ATOM   7390 C  C   . ILE C 3 206 ? 175.080 145.039 92.548  1.00 126.48 ? 206 ILE L C   1 
ATOM   7391 O  O   . ILE C 3 206 ? 175.826 145.805 93.169  1.00 126.48 ? 206 ILE L O   1 
ATOM   7392 C  CB  . ILE C 3 206 ? 173.062 144.560 94.015  1.00 126.48 ? 206 ILE L CB  1 
ATOM   7393 C  CG1 . ILE C 3 206 ? 172.205 145.412 93.073  1.00 126.48 ? 206 ILE L CG1 1 
ATOM   7394 C  CG2 . ILE C 3 206 ? 173.482 145.321 95.276  1.00 126.48 ? 206 ILE L CG2 1 
ATOM   7395 C  CD1 . ILE C 3 206 ? 170.841 145.757 93.629  1.00 126.48 ? 206 ILE L CD1 1 
ATOM   7396 N  N   . VAL C 3 207 ? 174.955 145.075 91.224  1.00 130.95 ? 207 VAL L N   1 
ATOM   7397 C  CA  . VAL C 3 207 ? 175.747 145.974 90.400  1.00 130.95 ? 207 VAL L CA  1 
ATOM   7398 C  C   . VAL C 3 207 ? 174.819 146.938 89.674  1.00 130.95 ? 207 VAL L C   1 
ATOM   7399 O  O   . VAL C 3 207 ? 173.652 146.643 89.402  1.00 130.95 ? 207 VAL L O   1 
ATOM   7400 C  CB  . VAL C 3 207 ? 176.636 145.208 89.397  1.00 130.95 ? 207 VAL L CB  1 
ATOM   7401 C  CG1 . VAL C 3 207 ? 177.650 144.351 90.139  1.00 130.95 ? 207 VAL L CG1 1 
ATOM   7402 C  CG2 . VAL C 3 207 ? 175.789 144.345 88.475  1.00 130.95 ? 207 VAL L CG2 1 
ATOM   7403 N  N   . LYS C 3 208 ? 175.358 148.119 89.377  1.00 130.28 ? 208 LYS L N   1 
ATOM   7404 C  CA  . LYS C 3 208 ? 174.626 149.138 88.629  1.00 130.28 ? 208 LYS L CA  1 
ATOM   7405 C  C   . LYS C 3 208 ? 175.660 150.037 87.966  1.00 130.28 ? 208 LYS L C   1 
ATOM   7406 O  O   . LYS C 3 208 ? 176.294 150.852 88.643  1.00 130.28 ? 208 LYS L O   1 
ATOM   7407 C  CB  . LYS C 3 208 ? 173.702 149.933 89.543  1.00 130.28 ? 208 LYS L CB  1 
ATOM   7408 C  CG  . LYS C 3 208 ? 172.826 150.938 88.818  1.00 130.28 ? 208 LYS L CG  1 
ATOM   7409 C  CD  . LYS C 3 208 ? 171.634 150.268 88.158  1.00 130.28 ? 208 LYS L CD  1 
ATOM   7410 C  CE  . LYS C 3 208 ? 170.694 149.679 89.194  1.00 130.28 ? 208 LYS L CE  1 
ATOM   7411 N  NZ  . LYS C 3 208 ? 169.742 148.708 88.590  1.00 130.28 ? 208 LYS L NZ  1 
ATOM   7412 N  N   . SER C 3 209 ? 175.824 149.890 86.657  1.00 134.54 ? 209 SER L N   1 
ATOM   7413 C  CA  . SER C 3 209 ? 176.856 150.587 85.909  1.00 134.54 ? 209 SER L CA  1 
ATOM   7414 C  C   . SER C 3 209 ? 176.257 151.735 85.109  1.00 134.54 ? 209 SER L C   1 
ATOM   7415 O  O   . SER C 3 209 ? 175.045 151.809 84.892  1.00 134.54 ? 209 SER L O   1 
ATOM   7416 C  CB  . SER C 3 209 ? 177.589 149.627 84.966  1.00 134.54 ? 209 SER L CB  1 
ATOM   7417 O  OG  . SER C 3 209 ? 178.435 150.335 84.077  1.00 134.54 ? 209 SER L OG  1 
ATOM   7418 N  N   . PHE C 3 210 ? 177.132 152.638 84.675  1.00 137.66 ? 210 PHE L N   1 
ATOM   7419 C  CA  . PHE C 3 210 ? 176.736 153.719 83.788  1.00 137.66 ? 210 PHE L CA  1 
ATOM   7420 C  C   . PHE C 3 210 ? 177.924 154.111 82.923  1.00 137.66 ? 210 PHE L C   1 
ATOM   7421 O  O   . PHE C 3 210 ? 179.080 153.843 83.260  1.00 137.66 ? 210 PHE L O   1 
ATOM   7422 C  CB  . PHE C 3 210 ? 176.212 154.934 84.561  1.00 137.66 ? 210 PHE L CB  1 
ATOM   7423 C  CG  . PHE C 3 210 ? 175.115 155.669 83.848  1.00 137.66 ? 210 PHE L CG  1 
ATOM   7424 C  CD1 . PHE C 3 210 ? 173.808 155.211 83.904  1.00 137.66 ? 210 PHE L CD1 1 
ATOM   7425 C  CD2 . PHE C 3 210 ? 175.393 156.805 83.106  1.00 137.66 ? 210 PHE L CD2 1 
ATOM   7426 C  CE1 . PHE C 3 210 ? 172.795 155.881 83.242  1.00 137.66 ? 210 PHE L CE1 1 
ATOM   7427 C  CE2 . PHE C 3 210 ? 174.386 157.479 82.439  1.00 137.66 ? 210 PHE L CE2 1 
ATOM   7428 C  CZ  . PHE C 3 210 ? 173.085 157.016 82.509  1.00 137.66 ? 210 PHE L CZ  1 
ATOM   7429 N  N   . ASN C 3 211 ? 177.621 154.754 81.799  1.00 137.88 ? 211 ASN L N   1 
ATOM   7430 C  CA  . ASN C 3 211 ? 178.629 155.190 80.847  1.00 137.88 ? 211 ASN L CA  1 
ATOM   7431 C  C   . ASN C 3 211 ? 178.457 156.677 80.575  1.00 137.88 ? 211 ASN L C   1 
ATOM   7432 O  O   . ASN C 3 211 ? 177.337 157.197 80.565  1.00 137.88 ? 211 ASN L O   1 
ATOM   7433 C  CB  . ASN C 3 211 ? 178.539 154.396 79.535  1.00 137.88 ? 211 ASN L CB  1 
ATOM   7434 C  CG  . ASN C 3 211 ? 179.692 154.687 78.596  1.00 137.88 ? 211 ASN L CG  1 
ATOM   7435 O  OD1 . ASN C 3 211 ? 179.488 155.022 77.429  1.00 137.88 ? 211 ASN L OD1 1 
ATOM   7436 N  ND2 . ASN C 3 211 ? 180.914 154.561 79.101  1.00 137.88 ? 211 ASN L ND2 1 
ATOM   7437 N  N   . ARG C 3 212 ? 179.585 157.358 80.361  1.00 137.90 ? 212 ARG L N   1 
ATOM   7438 C  CA  . ARG C 3 212 ? 179.564 158.797 80.125  1.00 137.90 ? 212 ARG L CA  1 
ATOM   7439 C  C   . ARG C 3 212 ? 178.920 159.162 78.795  1.00 137.90 ? 212 ARG L C   1 
ATOM   7440 O  O   . ARG C 3 212 ? 178.351 160.254 78.691  1.00 137.90 ? 212 ARG L O   1 
ATOM   7441 C  CB  . ARG C 3 212 ? 180.986 159.359 80.185  1.00 137.90 ? 212 ARG L CB  1 
ATOM   7442 N  N   . ASN C 3 213 ? 178.990 158.259 77.809  1.00 138.69 ? 213 ASN L N   1 
ATOM   7443 C  CA  . ASN C 3 213 ? 178.482 158.369 76.421  1.00 138.69 ? 213 ASN L CA  1 
ATOM   7444 C  C   . ASN C 3 213 ? 178.164 159.758 75.851  1.00 138.69 ? 213 ASN L C   1 
ATOM   7445 O  O   . ASN C 3 213 ? 177.178 159.936 75.138  1.00 138.69 ? 213 ASN L O   1 
ATOM   7446 C  CB  . ASN C 3 213 ? 177.238 157.472 76.265  1.00 138.69 ? 213 ASN L CB  1 
ATOM   7447 C  CG  . ASN C 3 213 ? 176.133 157.779 77.274  1.00 138.69 ? 213 ASN L CG  1 
ATOM   7448 O  OD1 . ASN C 3 213 ? 176.030 158.882 77.807  1.00 138.69 ? 213 ASN L OD1 1 
ATOM   7449 N  ND2 . ASN C 3 213 ? 175.297 156.781 77.538  1.00 138.69 ? 213 ASN L ND2 1 
HETATM 7450 CL CL  . CL  D 4 .   ? 157.936 163.255 174.058 1.00 86.19  ? 800 CL  A CL  1 
# 
