data_9CMB
# 
_entry.id   9CMB 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CMB         pdb_00009cmb 10.2210/pdb9cmb/pdb 
WWPDB D_1000285919 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-18 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CMB 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        'Identical complex in different space group' 
_pdbx_database_related.db_id          8E3K 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gpoon@gsu.edu 
_pdbx_contact_author.name_first         Gregory 
_pdbx_contact_author.name_last          Poon 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5107-9458 
# 
_audit_author.name               'Poon, G.M.K.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0001-5107-9458 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Human PU.1 ETS Domain (165-270) bound to d(AATAAAAGGAAGTGGG)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Poon, G.M.K.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   0000-0001-5107-9458 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Transcription factor PU.1'                                      12436.583 2  ? ? 
'ETS-Domain UNP residues 165-270' ? 
2 polymer     syn 
;DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3')
;
5044.317  2  ? ? ?                                 ? 
3 polymer     syn 
;DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3')
;
4750.089  2  ? ? ?                                 ? 
4 non-polymer syn 'ZINC ION'                                                       65.409    1  ? ? ? ? 
5 water       nat water                                                            18.015    94 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        '31 kDa-transforming protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;GSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKV
KKKLTYQFSGEVLGRGGLAERRHPPH
;
;GSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKV
KKKLTYQFSGEVLGRGGLAERRHPPH
;
A,C ? 
2 polydeoxyribonucleotide no no '(DA)(DA)(DT)(DA)(DA)(DA)(DA)(DG)(DG)(DA)(DA)(DG)(DT)(DG)(DG)(DG)' AATAAAAGGAAGTGGG B,D ? 
3 polydeoxyribonucleotide no no '(DT)(DC)(DC)(DC)(DA)(DC)(DT)(DT)(DC)(DC)(DT)(DT)(DT)(DT)(DA)(DT)' TCCCACTTCCTTTTAT E,F ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'ZINC ION' ZN  
5 water      HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   LYS n 
1 4   LYS n 
1 5   LYS n 
1 6   ILE n 
1 7   ARG n 
1 8   LEU n 
1 9   TYR n 
1 10  GLN n 
1 11  PHE n 
1 12  LEU n 
1 13  LEU n 
1 14  ASP n 
1 15  LEU n 
1 16  LEU n 
1 17  ARG n 
1 18  SER n 
1 19  GLY n 
1 20  ASP n 
1 21  MET n 
1 22  LYS n 
1 23  ASP n 
1 24  SER n 
1 25  ILE n 
1 26  TRP n 
1 27  TRP n 
1 28  VAL n 
1 29  ASP n 
1 30  LYS n 
1 31  ASP n 
1 32  LYS n 
1 33  GLY n 
1 34  THR n 
1 35  PHE n 
1 36  GLN n 
1 37  PHE n 
1 38  SER n 
1 39  SER n 
1 40  LYS n 
1 41  HIS n 
1 42  LYS n 
1 43  GLU n 
1 44  ALA n 
1 45  LEU n 
1 46  ALA n 
1 47  HIS n 
1 48  ARG n 
1 49  TRP n 
1 50  GLY n 
1 51  ILE n 
1 52  GLN n 
1 53  LYS n 
1 54  GLY n 
1 55  ASN n 
1 56  ARG n 
1 57  LYS n 
1 58  LYS n 
1 59  MET n 
1 60  THR n 
1 61  TYR n 
1 62  GLN n 
1 63  LYS n 
1 64  MET n 
1 65  ALA n 
1 66  ARG n 
1 67  ALA n 
1 68  LEU n 
1 69  ARG n 
1 70  ASN n 
1 71  TYR n 
1 72  GLY n 
1 73  LYS n 
1 74  THR n 
1 75  GLY n 
1 76  GLU n 
1 77  VAL n 
1 78  LYS n 
1 79  LYS n 
1 80  VAL n 
1 81  LYS n 
1 82  LYS n 
1 83  LYS n 
1 84  LEU n 
1 85  THR n 
1 86  TYR n 
1 87  GLN n 
1 88  PHE n 
1 89  SER n 
1 90  GLY n 
1 91  GLU n 
1 92  VAL n 
1 93  LEU n 
1 94  GLY n 
1 95  ARG n 
1 96  GLY n 
1 97  GLY n 
1 98  LEU n 
1 99  ALA n 
1 100 GLU n 
1 101 ARG n 
1 102 ARG n 
1 103 HIS n 
1 104 PRO n 
1 105 PRO n 
1 106 HIS n 
2 1   DA  n 
2 2   DA  n 
2 3   DT  n 
2 4   DA  n 
2 5   DA  n 
2 6   DA  n 
2 7   DA  n 
2 8   DG  n 
2 9   DG  n 
2 10  DA  n 
2 11  DA  n 
2 12  DG  n 
2 13  DT  n 
2 14  DG  n 
2 15  DG  n 
2 16  DG  n 
3 1   DT  n 
3 2   DC  n 
3 3   DC  n 
3 4   DC  n 
3 5   DA  n 
3 6   DC  n 
3 7   DT  n 
3 8   DT  n 
3 9   DC  n 
3 10  DC  n 
3 11  DT  n 
3 12  DT  n 
3 13  DT  n 
3 14  DT  n 
3 15  DA  n 
3 16  DT  n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   106 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SPI1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              Star 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
2 1 sample 1 16 'synthetic construct' ? 32630 ? 
3 1 sample 1 16 'synthetic construct' ? 32630 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                ? 'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
ZN  non-polymer         . 'ZINC ION'                           ? 'Zn 2'            65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   165 ?   ?   ?   A . n 
A 1 2   SER 2   166 ?   ?   ?   A . n 
A 1 3   LYS 3   167 ?   ?   ?   A . n 
A 1 4   LYS 4   168 ?   ?   ?   A . n 
A 1 5   LYS 5   169 169 LYS LYS A . n 
A 1 6   ILE 6   170 170 ILE ILE A . n 
A 1 7   ARG 7   171 171 ARG ARG A . n 
A 1 8   LEU 8   172 172 LEU LEU A . n 
A 1 9   TYR 9   173 173 TYR TYR A . n 
A 1 10  GLN 10  174 174 GLN GLN A . n 
A 1 11  PHE 11  175 175 PHE PHE A . n 
A 1 12  LEU 12  176 176 LEU LEU A . n 
A 1 13  LEU 13  177 177 LEU LEU A . n 
A 1 14  ASP 14  178 178 ASP ASP A . n 
A 1 15  LEU 15  179 179 LEU LEU A . n 
A 1 16  LEU 16  180 180 LEU LEU A . n 
A 1 17  ARG 17  181 181 ARG ARG A . n 
A 1 18  SER 18  182 182 SER SER A . n 
A 1 19  GLY 19  183 183 GLY GLY A . n 
A 1 20  ASP 20  184 184 ASP ASP A . n 
A 1 21  MET 21  185 185 MET MET A . n 
A 1 22  LYS 22  186 186 LYS LYS A . n 
A 1 23  ASP 23  187 187 ASP ASP A . n 
A 1 24  SER 24  188 188 SER SER A . n 
A 1 25  ILE 25  189 189 ILE ILE A . n 
A 1 26  TRP 26  190 190 TRP TRP A . n 
A 1 27  TRP 27  191 191 TRP TRP A . n 
A 1 28  VAL 28  192 192 VAL VAL A . n 
A 1 29  ASP 29  193 193 ASP ASP A . n 
A 1 30  LYS 30  194 194 LYS LYS A . n 
A 1 31  ASP 31  195 195 ASP ASP A . n 
A 1 32  LYS 32  196 196 LYS LYS A . n 
A 1 33  GLY 33  197 197 GLY GLY A . n 
A 1 34  THR 34  198 198 THR THR A . n 
A 1 35  PHE 35  199 199 PHE PHE A . n 
A 1 36  GLN 36  200 200 GLN GLN A . n 
A 1 37  PHE 37  201 201 PHE PHE A . n 
A 1 38  SER 38  202 202 SER SER A . n 
A 1 39  SER 39  203 203 SER SER A . n 
A 1 40  LYS 40  204 204 LYS LYS A . n 
A 1 41  HIS 41  205 205 HIS HIS A . n 
A 1 42  LYS 42  206 206 LYS LYS A . n 
A 1 43  GLU 43  207 207 GLU GLU A . n 
A 1 44  ALA 44  208 208 ALA ALA A . n 
A 1 45  LEU 45  209 209 LEU LEU A . n 
A 1 46  ALA 46  210 210 ALA ALA A . n 
A 1 47  HIS 47  211 211 HIS HIS A . n 
A 1 48  ARG 48  212 212 ARG ARG A . n 
A 1 49  TRP 49  213 213 TRP TRP A . n 
A 1 50  GLY 50  214 214 GLY GLY A . n 
A 1 51  ILE 51  215 215 ILE ILE A . n 
A 1 52  GLN 52  216 216 GLN GLN A . n 
A 1 53  LYS 53  217 217 LYS LYS A . n 
A 1 54  GLY 54  218 218 GLY GLY A . n 
A 1 55  ASN 55  219 219 ASN ASN A . n 
A 1 56  ARG 56  220 220 ARG ARG A . n 
A 1 57  LYS 57  221 221 LYS LYS A . n 
A 1 58  LYS 58  222 222 LYS LYS A . n 
A 1 59  MET 59  223 223 MET MET A . n 
A 1 60  THR 60  224 224 THR THR A . n 
A 1 61  TYR 61  225 225 TYR TYR A . n 
A 1 62  GLN 62  226 226 GLN GLN A . n 
A 1 63  LYS 63  227 227 LYS LYS A . n 
A 1 64  MET 64  228 228 MET MET A . n 
A 1 65  ALA 65  229 229 ALA ALA A . n 
A 1 66  ARG 66  230 230 ARG ARG A . n 
A 1 67  ALA 67  231 231 ALA ALA A . n 
A 1 68  LEU 68  232 232 LEU LEU A . n 
A 1 69  ARG 69  233 233 ARG ARG A . n 
A 1 70  ASN 70  234 234 ASN ASN A . n 
A 1 71  TYR 71  235 235 TYR TYR A . n 
A 1 72  GLY 72  236 236 GLY GLY A . n 
A 1 73  LYS 73  237 237 LYS LYS A . n 
A 1 74  THR 74  238 238 THR THR A . n 
A 1 75  GLY 75  239 239 GLY GLY A . n 
A 1 76  GLU 76  240 240 GLU GLU A . n 
A 1 77  VAL 77  241 241 VAL VAL A . n 
A 1 78  LYS 78  242 242 LYS LYS A . n 
A 1 79  LYS 79  243 243 LYS LYS A . n 
A 1 80  VAL 80  244 244 VAL VAL A . n 
A 1 81  LYS 81  245 245 LYS LYS A . n 
A 1 82  LYS 82  246 246 LYS LYS A . n 
A 1 83  LYS 83  247 247 LYS LYS A . n 
A 1 84  LEU 84  248 248 LEU LEU A . n 
A 1 85  THR 85  249 249 THR THR A . n 
A 1 86  TYR 86  250 250 TYR TYR A . n 
A 1 87  GLN 87  251 251 GLN GLN A . n 
A 1 88  PHE 88  252 252 PHE PHE A . n 
A 1 89  SER 89  253 253 SER SER A . n 
A 1 90  GLY 90  254 254 GLY GLY A . n 
A 1 91  GLU 91  255 255 GLU GLU A . n 
A 1 92  VAL 92  256 256 VAL VAL A . n 
A 1 93  LEU 93  257 257 LEU LEU A . n 
A 1 94  GLY 94  258 258 GLY GLY A . n 
A 1 95  ARG 95  259 259 ARG ARG A . n 
A 1 96  GLY 96  260 ?   ?   ?   A . n 
A 1 97  GLY 97  261 ?   ?   ?   A . n 
A 1 98  LEU 98  262 ?   ?   ?   A . n 
A 1 99  ALA 99  263 ?   ?   ?   A . n 
A 1 100 GLU 100 264 ?   ?   ?   A . n 
A 1 101 ARG 101 265 ?   ?   ?   A . n 
A 1 102 ARG 102 266 ?   ?   ?   A . n 
A 1 103 HIS 103 267 ?   ?   ?   A . n 
A 1 104 PRO 104 268 ?   ?   ?   A . n 
A 1 105 PRO 105 269 ?   ?   ?   A . n 
A 1 106 HIS 106 270 ?   ?   ?   A . n 
B 2 1   DA  1   1   1   DA  DA  B . n 
B 2 2   DA  2   2   2   DA  DA  B . n 
B 2 3   DT  3   3   3   DT  DT  B . n 
B 2 4   DA  4   4   4   DA  DA  B . n 
B 2 5   DA  5   5   5   DA  DA  B . n 
B 2 6   DA  6   6   6   DA  DA  B . n 
B 2 7   DA  7   7   7   DA  DA  B . n 
B 2 8   DG  8   8   8   DG  DG  B . n 
B 2 9   DG  9   9   9   DG  DG  B . n 
B 2 10  DA  10  10  10  DA  DA  B . n 
B 2 11  DA  11  11  11  DA  DA  B . n 
B 2 12  DG  12  12  12  DG  DG  B . n 
B 2 13  DT  13  13  13  DT  DT  B . n 
B 2 14  DG  14  14  14  DG  DG  B . n 
B 2 15  DG  15  15  15  DG  DG  B . n 
B 2 16  DG  16  16  16  DG  DG  B . n 
C 1 1   GLY 1   165 ?   ?   ?   C . n 
C 1 2   SER 2   166 ?   ?   ?   C . n 
C 1 3   LYS 3   167 ?   ?   ?   C . n 
C 1 4   LYS 4   168 ?   ?   ?   C . n 
C 1 5   LYS 5   169 169 LYS LYS C . n 
C 1 6   ILE 6   170 170 ILE ILE C . n 
C 1 7   ARG 7   171 171 ARG ARG C . n 
C 1 8   LEU 8   172 172 LEU LEU C . n 
C 1 9   TYR 9   173 173 TYR TYR C . n 
C 1 10  GLN 10  174 174 GLN GLN C . n 
C 1 11  PHE 11  175 175 PHE PHE C . n 
C 1 12  LEU 12  176 176 LEU LEU C . n 
C 1 13  LEU 13  177 177 LEU LEU C . n 
C 1 14  ASP 14  178 178 ASP ASP C . n 
C 1 15  LEU 15  179 179 LEU LEU C . n 
C 1 16  LEU 16  180 180 LEU LEU C . n 
C 1 17  ARG 17  181 181 ARG ARG C . n 
C 1 18  SER 18  182 182 SER SER C . n 
C 1 19  GLY 19  183 183 GLY GLY C . n 
C 1 20  ASP 20  184 184 ASP ASP C . n 
C 1 21  MET 21  185 185 MET MET C . n 
C 1 22  LYS 22  186 186 LYS LYS C . n 
C 1 23  ASP 23  187 187 ASP ASP C . n 
C 1 24  SER 24  188 188 SER SER C . n 
C 1 25  ILE 25  189 189 ILE ILE C . n 
C 1 26  TRP 26  190 190 TRP TRP C . n 
C 1 27  TRP 27  191 191 TRP TRP C . n 
C 1 28  VAL 28  192 192 VAL VAL C . n 
C 1 29  ASP 29  193 193 ASP ASP C . n 
C 1 30  LYS 30  194 194 LYS LYS C . n 
C 1 31  ASP 31  195 195 ASP ASP C . n 
C 1 32  LYS 32  196 196 LYS LYS C . n 
C 1 33  GLY 33  197 197 GLY GLY C . n 
C 1 34  THR 34  198 198 THR THR C . n 
C 1 35  PHE 35  199 199 PHE PHE C . n 
C 1 36  GLN 36  200 200 GLN GLN C . n 
C 1 37  PHE 37  201 201 PHE PHE C . n 
C 1 38  SER 38  202 202 SER SER C . n 
C 1 39  SER 39  203 203 SER SER C . n 
C 1 40  LYS 40  204 204 LYS LYS C . n 
C 1 41  HIS 41  205 205 HIS HIS C . n 
C 1 42  LYS 42  206 206 LYS LYS C . n 
C 1 43  GLU 43  207 207 GLU GLU C . n 
C 1 44  ALA 44  208 208 ALA ALA C . n 
C 1 45  LEU 45  209 209 LEU LEU C . n 
C 1 46  ALA 46  210 210 ALA ALA C . n 
C 1 47  HIS 47  211 211 HIS HIS C . n 
C 1 48  ARG 48  212 212 ARG ARG C . n 
C 1 49  TRP 49  213 213 TRP TRP C . n 
C 1 50  GLY 50  214 214 GLY GLY C . n 
C 1 51  ILE 51  215 215 ILE ILE C . n 
C 1 52  GLN 52  216 216 GLN GLN C . n 
C 1 53  LYS 53  217 217 LYS LYS C . n 
C 1 54  GLY 54  218 218 GLY GLY C . n 
C 1 55  ASN 55  219 219 ASN ASN C . n 
C 1 56  ARG 56  220 220 ARG ARG C . n 
C 1 57  LYS 57  221 221 LYS LYS C . n 
C 1 58  LYS 58  222 222 LYS LYS C . n 
C 1 59  MET 59  223 223 MET MET C . n 
C 1 60  THR 60  224 224 THR THR C . n 
C 1 61  TYR 61  225 225 TYR TYR C . n 
C 1 62  GLN 62  226 226 GLN GLN C . n 
C 1 63  LYS 63  227 227 LYS LYS C . n 
C 1 64  MET 64  228 228 MET MET C . n 
C 1 65  ALA 65  229 229 ALA ALA C . n 
C 1 66  ARG 66  230 230 ARG ARG C . n 
C 1 67  ALA 67  231 231 ALA ALA C . n 
C 1 68  LEU 68  232 232 LEU LEU C . n 
C 1 69  ARG 69  233 233 ARG ARG C . n 
C 1 70  ASN 70  234 234 ASN ASN C . n 
C 1 71  TYR 71  235 235 TYR TYR C . n 
C 1 72  GLY 72  236 236 GLY GLY C . n 
C 1 73  LYS 73  237 237 LYS LYS C . n 
C 1 74  THR 74  238 238 THR THR C . n 
C 1 75  GLY 75  239 239 GLY GLY C . n 
C 1 76  GLU 76  240 240 GLU GLU C . n 
C 1 77  VAL 77  241 241 VAL VAL C . n 
C 1 78  LYS 78  242 242 LYS LYS C . n 
C 1 79  LYS 79  243 243 LYS LYS C . n 
C 1 80  VAL 80  244 244 VAL VAL C . n 
C 1 81  LYS 81  245 245 LYS LYS C . n 
C 1 82  LYS 82  246 246 LYS LYS C . n 
C 1 83  LYS 83  247 247 LYS LYS C . n 
C 1 84  LEU 84  248 248 LEU LEU C . n 
C 1 85  THR 85  249 249 THR THR C . n 
C 1 86  TYR 86  250 250 TYR TYR C . n 
C 1 87  GLN 87  251 251 GLN GLN C . n 
C 1 88  PHE 88  252 252 PHE PHE C . n 
C 1 89  SER 89  253 253 SER SER C . n 
C 1 90  GLY 90  254 254 GLY GLY C . n 
C 1 91  GLU 91  255 255 GLU GLU C . n 
C 1 92  VAL 92  256 256 VAL VAL C . n 
C 1 93  LEU 93  257 257 LEU LEU C . n 
C 1 94  GLY 94  258 258 GLY GLY C . n 
C 1 95  ARG 95  259 259 ARG ARG C . n 
C 1 96  GLY 96  260 ?   ?   ?   C . n 
C 1 97  GLY 97  261 ?   ?   ?   C . n 
C 1 98  LEU 98  262 ?   ?   ?   C . n 
C 1 99  ALA 99  263 ?   ?   ?   C . n 
C 1 100 GLU 100 264 ?   ?   ?   C . n 
C 1 101 ARG 101 265 ?   ?   ?   C . n 
C 1 102 ARG 102 266 ?   ?   ?   C . n 
C 1 103 HIS 103 267 ?   ?   ?   C . n 
C 1 104 PRO 104 268 ?   ?   ?   C . n 
C 1 105 PRO 105 269 ?   ?   ?   C . n 
C 1 106 HIS 106 270 ?   ?   ?   C . n 
D 2 1   DA  1   1   1   DA  DA  D . n 
D 2 2   DA  2   2   2   DA  DA  D . n 
D 2 3   DT  3   3   3   DT  DT  D . n 
D 2 4   DA  4   4   4   DA  DA  D . n 
D 2 5   DA  5   5   5   DA  DA  D . n 
D 2 6   DA  6   6   6   DA  DA  D . n 
D 2 7   DA  7   7   7   DA  DA  D . n 
D 2 8   DG  8   8   8   DG  DG  D . n 
D 2 9   DG  9   9   9   DG  DG  D . n 
D 2 10  DA  10  10  10  DA  DA  D . n 
D 2 11  DA  11  11  11  DA  DA  D . n 
D 2 12  DG  12  12  12  DG  DG  D . n 
D 2 13  DT  13  13  13  DT  DT  D . n 
D 2 14  DG  14  14  14  DG  DG  D . n 
D 2 15  DG  15  15  15  DG  DG  D . n 
D 2 16  DG  16  16  16  DG  DG  D . n 
E 3 1   DT  1   17  17  DT  DT  E . n 
E 3 2   DC  2   18  18  DC  DC  E . n 
E 3 3   DC  3   19  19  DC  DC  E . n 
E 3 4   DC  4   20  20  DC  DC  E . n 
E 3 5   DA  5   21  21  DA  DA  E . n 
E 3 6   DC  6   22  22  DC  DC  E . n 
E 3 7   DT  7   23  23  DT  DT  E . n 
E 3 8   DT  8   24  24  DT  DT  E . n 
E 3 9   DC  9   25  25  DC  DC  E . n 
E 3 10  DC  10  26  26  DC  DC  E . n 
E 3 11  DT  11  27  27  DT  DT  E . n 
E 3 12  DT  12  28  28  DT  DT  E . n 
E 3 13  DT  13  29  29  DT  DT  E . n 
E 3 14  DT  14  30  30  DT  DT  E . n 
E 3 15  DA  15  31  31  DA  DA  E . n 
E 3 16  DT  16  32  32  DT  DT  E . n 
F 3 1   DT  1   17  17  DT  DT  F . n 
F 3 2   DC  2   18  18  DC  DC  F . n 
F 3 3   DC  3   19  19  DC  DC  F . n 
F 3 4   DC  4   20  20  DC  DC  F . n 
F 3 5   DA  5   21  21  DA  DA  F . n 
F 3 6   DC  6   22  22  DC  DC  F . n 
F 3 7   DT  7   23  23  DT  DT  F . n 
F 3 8   DT  8   24  24  DT  DT  F . n 
F 3 9   DC  9   25  25  DC  DC  F . n 
F 3 10  DC  10  26  26  DC  DC  F . n 
F 3 11  DT  11  27  27  DT  DT  F . n 
F 3 12  DT  12  28  28  DT  DT  F . n 
F 3 13  DT  13  29  29  DT  DT  F . n 
F 3 14  DT  14  30  30  DT  DT  F . n 
F 3 15  DA  15  31  31  DA  DA  F . n 
F 3 16  DT  16  32  32  DT  DT  F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 4 ZN  1  301 185  ZN  ZN  C . 
H 5 HOH 1  301 552  HOH HOH A . 
H 5 HOH 2  302 222  HOH HOH A . 
H 5 HOH 3  303 84   HOH HOH A . 
H 5 HOH 4  304 1199 HOH HOH A . 
H 5 HOH 5  305 183  HOH HOH A . 
H 5 HOH 6  306 368  HOH HOH A . 
H 5 HOH 7  307 328  HOH HOH A . 
H 5 HOH 8  308 470  HOH HOH A . 
H 5 HOH 9  309 29   HOH HOH A . 
H 5 HOH 10 310 562  HOH HOH A . 
H 5 HOH 11 311 325  HOH HOH A . 
H 5 HOH 12 312 783  HOH HOH A . 
H 5 HOH 13 313 146  HOH HOH A . 
H 5 HOH 14 314 591  HOH HOH A . 
H 5 HOH 15 315 223  HOH HOH A . 
H 5 HOH 16 316 193  HOH HOH A . 
H 5 HOH 17 317 4    HOH HOH A . 
H 5 HOH 18 318 305  HOH HOH A . 
H 5 HOH 19 319 1241 HOH HOH A . 
H 5 HOH 20 320 319  HOH HOH A . 
H 5 HOH 21 321 82   HOH HOH A . 
H 5 HOH 22 322 560  HOH HOH A . 
I 5 HOH 1  101 846  HOH HOH B . 
I 5 HOH 2  102 7    HOH HOH B . 
I 5 HOH 3  103 74   HOH HOH B . 
I 5 HOH 4  104 106  HOH HOH B . 
I 5 HOH 5  105 102  HOH HOH B . 
I 5 HOH 6  106 1    HOH HOH B . 
I 5 HOH 7  107 1265 HOH HOH B . 
I 5 HOH 8  108 178  HOH HOH B . 
I 5 HOH 9  109 795  HOH HOH B . 
I 5 HOH 10 110 601  HOH HOH B . 
I 5 HOH 11 111 1348 HOH HOH B . 
J 5 HOH 1  401 886  HOH HOH C . 
J 5 HOH 2  402 1236 HOH HOH C . 
J 5 HOH 3  403 202  HOH HOH C . 
J 5 HOH 4  404 885  HOH HOH C . 
J 5 HOH 5  405 1168 HOH HOH C . 
J 5 HOH 6  406 31   HOH HOH C . 
J 5 HOH 7  407 21   HOH HOH C . 
J 5 HOH 8  408 540  HOH HOH C . 
J 5 HOH 9  409 118  HOH HOH C . 
J 5 HOH 10 410 317  HOH HOH C . 
J 5 HOH 11 411 73   HOH HOH C . 
J 5 HOH 12 412 16   HOH HOH C . 
J 5 HOH 13 413 1230 HOH HOH C . 
J 5 HOH 14 414 291  HOH HOH C . 
J 5 HOH 15 415 282  HOH HOH C . 
J 5 HOH 16 416 8    HOH HOH C . 
J 5 HOH 17 417 547  HOH HOH C . 
J 5 HOH 18 418 89   HOH HOH C . 
J 5 HOH 19 419 54   HOH HOH C . 
J 5 HOH 20 420 1266 HOH HOH C . 
J 5 HOH 21 421 232  HOH HOH C . 
J 5 HOH 22 422 395  HOH HOH C . 
J 5 HOH 23 423 543  HOH HOH C . 
J 5 HOH 24 424 1237 HOH HOH C . 
J 5 HOH 25 425 700  HOH HOH C . 
J 5 HOH 26 426 635  HOH HOH C . 
K 5 HOH 1  101 541  HOH HOH D . 
K 5 HOH 2  102 1128 HOH HOH D . 
K 5 HOH 3  103 1242 HOH HOH D . 
K 5 HOH 4  104 1235 HOH HOH D . 
K 5 HOH 5  105 75   HOH HOH D . 
L 5 HOH 1  101 428  HOH HOH E . 
L 5 HOH 2  102 1077 HOH HOH E . 
L 5 HOH 3  103 45   HOH HOH E . 
L 5 HOH 4  104 310  HOH HOH E . 
L 5 HOH 5  105 434  HOH HOH E . 
L 5 HOH 6  106 1269 HOH HOH E . 
L 5 HOH 7  107 35   HOH HOH E . 
L 5 HOH 8  108 9    HOH HOH E . 
L 5 HOH 9  109 65   HOH HOH E . 
L 5 HOH 10 110 5    HOH HOH E . 
L 5 HOH 11 111 26   HOH HOH E . 
L 5 HOH 12 112 50   HOH HOH E . 
L 5 HOH 13 113 270  HOH HOH E . 
L 5 HOH 14 114 3    HOH HOH E . 
L 5 HOH 15 115 808  HOH HOH E . 
L 5 HOH 16 116 37   HOH HOH E . 
L 5 HOH 17 117 1343 HOH HOH E . 
L 5 HOH 18 118 110  HOH HOH E . 
L 5 HOH 19 119 1304 HOH HOH E . 
M 5 HOH 1  101 184  HOH HOH F . 
M 5 HOH 2  102 195  HOH HOH F . 
M 5 HOH 3  103 596  HOH HOH F . 
M 5 HOH 4  104 10   HOH HOH F . 
M 5 HOH 5  105 69   HOH HOH F . 
M 5 HOH 6  106 11   HOH HOH F . 
M 5 HOH 7  107 145  HOH HOH F . 
M 5 HOH 8  108 23   HOH HOH F . 
M 5 HOH 9  109 791  HOH HOH F . 
M 5 HOH 10 110 345  HOH HOH F . 
M 5 HOH 11 111 1355 HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 169 ? CG  ? A LYS 5  CG  
2  1 Y 1 A LYS 169 ? CD  ? A LYS 5  CD  
3  1 Y 1 A LYS 169 ? CE  ? A LYS 5  CE  
4  1 Y 1 A LYS 169 ? NZ  ? A LYS 5  NZ  
5  1 Y 0 A LYS 204 ? CE  ? A LYS 40 CE  
6  1 Y 0 A ARG 220 ? CZ  ? A ARG 56 CZ  
7  1 Y 0 A ARG 220 ? NH1 ? A ARG 56 NH1 
8  1 Y 0 A LYS 237 ? CG  ? A LYS 73 CG  
9  1 Y 0 A LYS 237 ? NZ  ? A LYS 73 NZ  
10 1 Y 0 A LYS 247 ? CE  ? A LYS 83 CE  
11 1 Y 1 A ARG 259 ? CG  ? A ARG 95 CG  
12 1 Y 1 A ARG 259 ? CD  ? A ARG 95 CD  
13 1 Y 1 A ARG 259 ? NE  ? A ARG 95 NE  
14 1 Y 1 A ARG 259 ? CZ  ? A ARG 95 CZ  
15 1 Y 1 A ARG 259 ? NH1 ? A ARG 95 NH1 
16 1 Y 1 A ARG 259 ? NH2 ? A ARG 95 NH2 
17 1 Y 1 C LYS 169 ? CG  ? C LYS 5  CG  
18 1 Y 1 C LYS 169 ? CD  ? C LYS 5  CD  
19 1 Y 1 C LYS 169 ? CE  ? C LYS 5  CE  
20 1 Y 1 C LYS 169 ? NZ  ? C LYS 5  NZ  
21 1 Y 0 C LYS 204 ? CE  ? C LYS 40 CE  
22 1 Y 0 C ARG 220 ? CZ  ? C ARG 56 CZ  
23 1 Y 0 C ARG 220 ? NH1 ? C ARG 56 NH1 
24 1 Y 0 C LYS 237 ? CG  ? C LYS 73 CG  
25 1 Y 0 C LYS 237 ? NZ  ? C LYS 73 NZ  
26 1 Y 1 C ARG 259 ? CG  ? C ARG 95 CG  
27 1 Y 1 C ARG 259 ? CD  ? C ARG 95 CD  
28 1 Y 1 C ARG 259 ? NE  ? C ARG 95 NE  
29 1 Y 1 C ARG 259 ? CZ  ? C ARG 95 CZ  
30 1 Y 1 C ARG 259 ? NH1 ? C ARG 95 NH1 
31 1 Y 1 C ARG 259 ? NH2 ? C ARG 95 NH2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_reference_DOI 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.21.1_5286 ? 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           ? 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           ? 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           ? 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   111.651 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CMB 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     90.954 
_cell.length_a_esd                 ? 
_cell.length_b                     102.731 
_cell.length_b_esd                 ? 
_cell.length_c                     55.753 
_cell.length_c_esd                 ? 
_cell.volume                       484191.169 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CMB 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            'C 2y' 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CMB 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.72 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          54.82 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM sodium cacodylate, pH 6.5, 200 mM zinc acetate and 2% PEG 600' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-10-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.920119 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'NSLS-II BEAMLINE 17-ID-2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.920119 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   17-ID-2 
_diffrn_source.pdbx_synchrotron_site       NSLS-II 
# 
_reflns.B_iso_Wilson_estimate                          42.47 
_reflns.entry_id                                       9CMB 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.15 
_reflns.d_resolution_low                               28.91 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     25670 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.09 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                1.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.075 
_reflns.pdbx_Rpim_I_all                                0.053 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.995 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.053 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.15 
_reflns_shell.d_res_low                                     2.23 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.7 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2547 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               1.8 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.676 
_reflns_shell.pdbx_Rpim_I_all                               0.478 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.780 
_reflns_shell.pdbx_CC_star                                  0.943 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.7 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.478 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               52.93 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CMB 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.15 
_refine.ls_d_res_low                             28.91 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     25670 
_refine.ls_number_reflns_R_free                  3658 
_refine.ls_number_reflns_R_work                  43571 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.1 
_refine.ls_percent_reflns_R_free                 7.75 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2342 
_refine.ls_R_factor_R_free                       0.2457 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2332 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 31.2620 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3025 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.15 
_refine_hist.d_res_low                        28.91 
_refine_hist.number_atoms_solvent             94 
_refine_hist.number_atoms_total               2897 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1502 
_refine_hist.pdbx_number_atoms_nucleic_acid   1300 
_refine_hist.pdbx_number_atoms_ligand         1 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_Zscore 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0146  ? 3002 ? f_bond_d           ? ? ? 
'X-RAY DIFFRACTION' ? 1.5528  ? 4298 ? f_angle_d          ? ? ? 
'X-RAY DIFFRACTION' ? 0.1000  ? 460  ? f_chiral_restr     ? ? ? 
'X-RAY DIFFRACTION' ? 0.0096  ? 316  ? f_plane_restr      ? ? ? 
'X-RAY DIFFRACTION' ? 25.9740 ? 1298 ? f_dihedral_angle_d ? ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.15 2.18  . . 134 1586 88.84 . . . . 0.3685 . . . . . . . . . . . . . . . 0.3604 
'X-RAY DIFFRACTION' 2.18 2.21  . . 139 1653 90.51 . . . . 0.3587 . . . . . . . . . . . . . . . 0.3541 
'X-RAY DIFFRACTION' 2.21 2.24  . . 133 1614 88.68 . . . . 0.3402 . . . . . . . . . . . . . . . 0.2855 
'X-RAY DIFFRACTION' 2.24 2.27  . . 141 1622 90.23 . . . . 0.3131 . . . . . . . . . . . . . . . 0.3246 
'X-RAY DIFFRACTION' 2.27 2.31  . . 140 1647 90.94 . . . . 0.2859 . . . . . . . . . . . . . . . 0.3612 
'X-RAY DIFFRACTION' 2.31 2.35  . . 142 1648 91.00 . . . . 0.3103 . . . . . . . . . . . . . . . 0.2888 
'X-RAY DIFFRACTION' 2.35 2.39  . . 135 1641 90.98 . . . . 0.2899 . . . . . . . . . . . . . . . 0.3159 
'X-RAY DIFFRACTION' 2.39 2.43  . . 143 1652 91.40 . . . . 0.2828 . . . . . . . . . . . . . . . 0.3089 
'X-RAY DIFFRACTION' 2.43 2.48  . . 130 1659 91.46 . . . . 0.2927 . . . . . . . . . . . . . . . 0.2958 
'X-RAY DIFFRACTION' 2.48 2.53  . . 142 1657 91.79 . . . . 0.2757 . . . . . . . . . . . . . . . 0.2785 
'X-RAY DIFFRACTION' 2.53 2.58  . . 142 1690 92.29 . . . . 0.2484 . . . . . . . . . . . . . . . 0.2906 
'X-RAY DIFFRACTION' 2.58 2.64  . . 138 1699 92.59 . . . . 0.2715 . . . . . . . . . . . . . . . 0.2850 
'X-RAY DIFFRACTION' 2.64 2.71  . . 134 1644 92.41 . . . . 0.2684 . . . . . . . . . . . . . . . 0.3059 
'X-RAY DIFFRACTION' 2.71 2.78  . . 136 1666 92.51 . . . . 0.2867 . . . . . . . . . . . . . . . 0.3025 
'X-RAY DIFFRACTION' 2.78 2.86  . . 143 1712 92.66 . . . . 0.2670 . . . . . . . . . . . . . . . 0.2997 
'X-RAY DIFFRACTION' 2.86 2.96  . . 141 1647 92.45 . . . . 0.2672 . . . . . . . . . . . . . . . 0.2591 
'X-RAY DIFFRACTION' 2.96 3.06  . . 143 1695 93.73 . . . . 0.2853 . . . . . . . . . . . . . . . 0.3063 
'X-RAY DIFFRACTION' 3.06 3.18  . . 143 1670 93.36 . . . . 0.2702 . . . . . . . . . . . . . . . 0.3541 
'X-RAY DIFFRACTION' 3.18 3.33  . . 143 1706 92.73 . . . . 0.2315 . . . . . . . . . . . . . . . 0.2115 
'X-RAY DIFFRACTION' 3.33 3.50  . . 145 1696 93.22 . . . . 0.2130 . . . . . . . . . . . . . . . 0.2168 
'X-RAY DIFFRACTION' 3.50 3.72  . . 142 1691 94.58 . . . . 0.2074 . . . . . . . . . . . . . . . 0.2477 
'X-RAY DIFFRACTION' 3.72 4.01  . . 140 1719 93.70 . . . . 0.1921 . . . . . . . . . . . . . . . 0.2221 
'X-RAY DIFFRACTION' 4.01 4.41  . . 141 1679 95.04 . . . . 0.1582 . . . . . . . . . . . . . . . 0.1732 
'X-RAY DIFFRACTION' 4.41 5.05  . . 151 1752 96.11 . . . . 0.1908 . . . . . . . . . . . . . . . 0.1951 
'X-RAY DIFFRACTION' 5.05 6.35  . . 145 1766 97.20 . . . . 0.2203 . . . . . . . . . . . . . . . 0.2282 
'X-RAY DIFFRACTION' 6.35 28.91 . . 152 1760 96.86 . . . . 0.2235 . . . . . . . . . . . . . . . 0.2136 
# 
_struct.entry_id                     9CMB 
_struct.title                        'Human PU.1 ETS Domain (165-270) bound to d(AATAAAAGGAAGTGGG)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CMB 
_struct_keywords.text            'ETS family transcription factor, DNA BINDING PROTEIN, DNA BINDING PROTEIN-DNA complex' 
_struct_keywords.pdbx_keywords   'DNA BINDING PROTEIN/DNA' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 5 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
L N N 5 ? 
M N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP SPI1_HUMAN P17947 ? 1 
;GSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKV
KKKLTYQFSGEVLGRGGLAERRHPPH
;
165 
2 PDB 9CMB       9CMB   ? 2 ? 1   
3 PDB 9CMB       9CMB   ? 3 ? 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CMB A 1 ? 106 ? P17947 165 ? 270 ? 165 270 
2 2 9CMB B 1 ? 16  ? 9CMB   1   ? 16  ? 1   16  
3 1 9CMB C 1 ? 106 ? P17947 165 ? 270 ? 165 270 
4 2 9CMB D 1 ? 16  ? 9CMB   1   ? 16  ? 1   16  
5 3 9CMB E 1 ? 16  ? 9CMB   17  ? 32  ? 17  32  
6 3 9CMB F 1 ? 16  ? 9CMB   17  ? 32  ? 17  32  
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA trimeric 3 
2 author_and_software_defined_assembly PISA trimeric 3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3370 ? 
1 MORE         -23  ? 
1 'SSA (A^2)'  9820 ? 
2 'ABSA (A^2)' 3470 ? 
2 MORE         -50  ? 
2 'SSA (A^2)'  9930 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,H,I,L   
2 1 C,D,F,G,J,K,M 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'native gel electrophoresis' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ARG A 7  ? GLY A 19 ? ARG A 171 GLY A 183 1 ? 13 
HELX_P HELX_P2 AA2 HIS A 41 ? GLY A 54 ? HIS A 205 GLY A 218 1 ? 14 
HELX_P HELX_P3 AA3 THR A 60 ? GLY A 75 ? THR A 224 GLY A 239 1 ? 16 
HELX_P HELX_P4 AA4 SER A 89 ? ARG A 95 ? SER A 253 ARG A 259 1 ? 7  
HELX_P HELX_P5 AA5 ARG C 7  ? GLY C 19 ? ARG C 171 GLY C 183 1 ? 13 
HELX_P HELX_P6 AA6 HIS C 41 ? GLY C 54 ? HIS C 205 GLY C 218 1 ? 14 
HELX_P HELX_P7 AA7 THR C 60 ? GLY C 75 ? THR C 224 GLY C 239 1 ? 16 
HELX_P HELX_P8 AA8 GLU C 91 ? ARG C 95 ? GLU C 255 ARG C 259 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? C ASP 23 OD2 ? ? ? 1_555 G ZN  .  ZN ? ? C ASP 187 C ZN  301 1_555 ? ? ? ? ? ? ?            2.406 ? ? 
metalc2  metalc ? ? C HIS 41 ND1 ? ? ? 1_555 G ZN  .  ZN ? ? C HIS 205 C ZN  301 2_556 ? ? ? ? ? ? ?            2.314 ? ? 
metalc3  metalc ? ? G ZN  .  ZN  ? ? ? 1_555 J HOH .  O  ? ? C ZN  301 C HOH 402 1_555 ? ? ? ? ? ? ?            2.340 ? ? 
metalc4  metalc ? ? G ZN  .  ZN  ? ? ? 1_555 J HOH .  O  ? ? C ZN  301 C HOH 424 2_556 ? ? ? ? ? ? ?            2.319 ? ? 
metalc5  metalc ? ? G ZN  .  ZN  ? ? ? 1_555 J HOH .  O  ? ? C ZN  301 C HOH 425 1_555 ? ? ? ? ? ? ?            2.279 ? ? 
hydrog1  hydrog ? ? B DA  2  N1  ? ? ? 1_555 E DT  16 N3 ? ? B DA  2   E DT  32  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog2  hydrog ? ? B DA  2  N6  ? ? ? 1_555 E DT  16 O4 ? ? B DA  2   E DT  32  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog3  hydrog ? ? B DT  3  N3  ? ? ? 1_555 E DA  15 N1 ? ? B DT  3   E DA  31  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog4  hydrog ? ? B DT  3  O4  ? ? ? 1_555 E DA  15 N6 ? ? B DT  3   E DA  31  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog5  hydrog ? ? B DA  4  N1  ? ? ? 1_555 E DT  14 N3 ? ? B DA  4   E DT  30  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog6  hydrog ? ? B DA  4  N6  ? ? ? 1_555 E DT  14 O4 ? ? B DA  4   E DT  30  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog7  hydrog ? ? B DA  5  N1  ? ? ? 1_555 E DT  13 N3 ? ? B DA  5   E DT  29  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog8  hydrog ? ? B DA  5  N6  ? ? ? 1_555 E DT  13 O4 ? ? B DA  5   E DT  29  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog9  hydrog ? ? B DA  6  N1  ? ? ? 1_555 E DT  12 N3 ? ? B DA  6   E DT  28  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog10 hydrog ? ? B DA  6  N6  ? ? ? 1_555 E DT  12 O4 ? ? B DA  6   E DT  28  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog11 hydrog ? ? B DA  7  N1  ? ? ? 1_555 E DT  11 N3 ? ? B DA  7   E DT  27  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog12 hydrog ? ? B DA  7  N6  ? ? ? 1_555 E DT  11 O4 ? ? B DA  7   E DT  27  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog13 hydrog ? ? B DG  8  N1  ? ? ? 1_555 E DC  10 N3 ? ? B DG  8   E DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog14 hydrog ? ? B DG  8  N2  ? ? ? 1_555 E DC  10 O2 ? ? B DG  8   E DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog15 hydrog ? ? B DG  8  O6  ? ? ? 1_555 E DC  10 N4 ? ? B DG  8   E DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog16 hydrog ? ? B DG  9  N1  ? ? ? 1_555 E DC  9  N3 ? ? B DG  9   E DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog17 hydrog ? ? B DG  9  N2  ? ? ? 1_555 E DC  9  O2 ? ? B DG  9   E DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog18 hydrog ? ? B DG  9  O6  ? ? ? 1_555 E DC  9  N4 ? ? B DG  9   E DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog19 hydrog ? ? B DA  10 N1  ? ? ? 1_555 E DT  8  N3 ? ? B DA  10  E DT  24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog20 hydrog ? ? B DA  10 N6  ? ? ? 1_555 E DT  8  O4 ? ? B DA  10  E DT  24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog21 hydrog ? ? B DA  11 N1  ? ? ? 1_555 E DT  7  N3 ? ? B DA  11  E DT  23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog22 hydrog ? ? B DA  11 N6  ? ? ? 1_555 E DT  7  O4 ? ? B DA  11  E DT  23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog23 hydrog ? ? B DG  12 N1  ? ? ? 1_555 E DC  6  N3 ? ? B DG  12  E DC  22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog24 hydrog ? ? B DG  12 N2  ? ? ? 1_555 E DC  6  O2 ? ? B DG  12  E DC  22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog25 hydrog ? ? B DG  12 O6  ? ? ? 1_555 E DC  6  N4 ? ? B DG  12  E DC  22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog26 hydrog ? ? B DT  13 N3  ? ? ? 1_555 E DA  5  N1 ? ? B DT  13  E DA  21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog27 hydrog ? ? B DT  13 O4  ? ? ? 1_555 E DA  5  N6 ? ? B DT  13  E DA  21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog28 hydrog ? ? B DG  14 O6  ? ? ? 1_555 E DC  4  N4 ? ? B DG  14  E DC  20  1_555 ? ? ? ? ? ? 'DG-DC PAIR' ?     ? ? 
hydrog29 hydrog ? ? B DG  15 N1  ? ? ? 1_555 E DC  3  N3 ? ? B DG  15  E DC  19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog30 hydrog ? ? B DG  15 N2  ? ? ? 1_555 E DC  3  O2 ? ? B DG  15  E DC  19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog31 hydrog ? ? B DG  15 O6  ? ? ? 1_555 E DC  3  N4 ? ? B DG  15  E DC  19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog32 hydrog ? ? B DG  16 N1  ? ? ? 1_555 E DC  2  N3 ? ? B DG  16  E DC  18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog33 hydrog ? ? B DG  16 N2  ? ? ? 1_555 E DC  2  O2 ? ? B DG  16  E DC  18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog34 hydrog ? ? B DG  16 O6  ? ? ? 1_555 E DC  2  N4 ? ? B DG  16  E DC  18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog35 hydrog ? ? D DA  2  N1  ? ? ? 1_555 F DT  16 N3 ? ? D DA  2   F DT  32  1_555 ? ? ? ? ? ? 'DA-DT PAIR' ?     ? ? 
hydrog36 hydrog ? ? D DT  3  N3  ? ? ? 1_555 F DA  15 N1 ? ? D DT  3   F DA  31  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog37 hydrog ? ? D DT  3  O4  ? ? ? 1_555 F DA  15 N6 ? ? D DT  3   F DA  31  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog38 hydrog ? ? D DA  4  N1  ? ? ? 1_555 F DT  14 N3 ? ? D DA  4   F DT  30  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog39 hydrog ? ? D DA  4  N6  ? ? ? 1_555 F DT  14 O4 ? ? D DA  4   F DT  30  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog40 hydrog ? ? D DA  5  N1  ? ? ? 1_555 F DT  13 N3 ? ? D DA  5   F DT  29  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog41 hydrog ? ? D DA  5  N6  ? ? ? 1_555 F DT  13 O4 ? ? D DA  5   F DT  29  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog42 hydrog ? ? D DA  6  N1  ? ? ? 1_555 F DT  12 N3 ? ? D DA  6   F DT  28  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog43 hydrog ? ? D DA  6  N6  ? ? ? 1_555 F DT  12 O4 ? ? D DA  6   F DT  28  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog44 hydrog ? ? D DA  7  N1  ? ? ? 1_555 F DT  11 N3 ? ? D DA  7   F DT  27  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog45 hydrog ? ? D DA  7  N6  ? ? ? 1_555 F DT  11 O4 ? ? D DA  7   F DT  27  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog46 hydrog ? ? D DG  8  N1  ? ? ? 1_555 F DC  10 N3 ? ? D DG  8   F DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog47 hydrog ? ? D DG  8  N2  ? ? ? 1_555 F DC  10 O2 ? ? D DG  8   F DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog48 hydrog ? ? D DG  8  O6  ? ? ? 1_555 F DC  10 N4 ? ? D DG  8   F DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog49 hydrog ? ? D DG  9  N1  ? ? ? 1_555 F DC  9  N3 ? ? D DG  9   F DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog50 hydrog ? ? D DG  9  N2  ? ? ? 1_555 F DC  9  O2 ? ? D DG  9   F DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog51 hydrog ? ? D DG  9  O6  ? ? ? 1_555 F DC  9  N4 ? ? D DG  9   F DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog52 hydrog ? ? D DA  10 N1  ? ? ? 1_555 F DT  8  N3 ? ? D DA  10  F DT  24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog53 hydrog ? ? D DA  10 N6  ? ? ? 1_555 F DT  8  O4 ? ? D DA  10  F DT  24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog54 hydrog ? ? D DA  11 N1  ? ? ? 1_555 F DT  7  N3 ? ? D DA  11  F DT  23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog55 hydrog ? ? D DA  11 N6  ? ? ? 1_555 F DT  7  O4 ? ? D DA  11  F DT  23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog56 hydrog ? ? D DG  12 N1  ? ? ? 1_555 F DC  6  N3 ? ? D DG  12  F DC  22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog57 hydrog ? ? D DG  12 N2  ? ? ? 1_555 F DC  6  O2 ? ? D DG  12  F DC  22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog58 hydrog ? ? D DG  12 O6  ? ? ? 1_555 F DC  6  N4 ? ? D DG  12  F DC  22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog59 hydrog ? ? D DT  13 N3  ? ? ? 1_555 F DA  5  N1 ? ? D DT  13  F DA  21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog60 hydrog ? ? D DT  13 O4  ? ? ? 1_555 F DA  5  N6 ? ? D DT  13  F DA  21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog61 hydrog ? ? D DG  14 O6  ? ? ? 1_555 F DC  4  N4 ? ? D DG  14  F DC  20  1_555 ? ? ? ? ? ? 'DG-DC PAIR' ?     ? ? 
hydrog62 hydrog ? ? D DG  15 N1  ? ? ? 1_555 F DC  3  N3 ? ? D DG  15  F DC  19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog63 hydrog ? ? D DG  15 N2  ? ? ? 1_555 F DC  3  O2 ? ? D DG  15  F DC  19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog64 hydrog ? ? D DG  15 O6  ? ? ? 1_555 F DC  3  N4 ? ? D DG  15  F DC  19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog65 hydrog ? ? D DG  16 N1  ? ? ? 1_555 F DC  2  N3 ? ? D DG  16  F DC  18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog66 hydrog ? ? D DG  16 N2  ? ? ? 1_555 F DC  2  O2 ? ? D DG  16  F DC  18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog67 hydrog ? ? D DG  16 O6  ? ? ? 1_555 F DC  2  N4 ? ? D DG  16  F DC  18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD2 ? C ASP 23 ? C ASP 187 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 ND1 ? C HIS 41 ? C HIS 205 ? 1_555 88.2  ? 
2  OD2 ? C ASP 23 ? C ASP 187 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 402 ? 1_555 60.9  ? 
3  ND1 ? C HIS 41 ? C HIS 205 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 402 ? 1_555 128.7 ? 
4  OD2 ? C ASP 23 ? C ASP 187 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 424 ? 2_556 110.5 ? 
5  ND1 ? C HIS 41 ? C HIS 205 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 424 ? 2_556 48.1  ? 
6  O   ? J HOH .  ? C HOH 402 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 424 ? 2_556 171.3 ? 
7  OD2 ? C ASP 23 ? C ASP 187 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 425 ? 1_555 99.4  ? 
8  ND1 ? C HIS 41 ? C HIS 205 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 425 ? 1_555 172.0 ? 
9  O   ? J HOH .  ? C HOH 402 ? 1_555 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 425 ? 1_555 54.8  ? 
10 O   ? J HOH .  ? C HOH 424 ? 2_556 ZN ? G ZN . ? C ZN 301 ? 1_555 O   ? J HOH .  ? C HOH 425 ? 1_555 129.7 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 25 ? ASP A 29 ? ILE A 189 ASP A 193 
AA1 2 THR A 34 ? PHE A 37 ? THR A 198 PHE A 201 
AA1 3 THR A 85 ? PHE A 88 ? THR A 249 PHE A 252 
AA1 4 VAL A 77 ? LYS A 79 ? VAL A 241 LYS A 243 
AA2 1 ILE C 25 ? ASP C 29 ? ILE C 189 ASP C 193 
AA2 2 THR C 34 ? PHE C 37 ? THR C 198 PHE C 201 
AA2 3 THR C 85 ? PHE C 88 ? THR C 249 PHE C 252 
AA2 4 VAL C 77 ? LYS C 79 ? VAL C 241 LYS C 243 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 28 ? N VAL A 192 O THR A 34 ? O THR A 198 
AA1 2 3 N PHE A 35 ? N PHE A 199 O TYR A 86 ? O TYR A 250 
AA1 3 4 O GLN A 87 ? O GLN A 251 N LYS A 78 ? N LYS A 242 
AA2 1 2 N VAL C 28 ? N VAL C 192 O THR C 34 ? O THR C 198 
AA2 2 3 N PHE C 35 ? N PHE C 199 O TYR C 86 ? O TYR C 250 
AA2 3 4 O GLN C 87 ? O GLN C 251 N LYS C 78 ? N LYS C 242 
# 
_pdbx_entry_details.entry_id                   9CMB 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HG C SER 253 ? ? O C HOH 401 ? ? 1.60 
2 1 O  C HOH 402 ? ? O C HOH 425 ? ? 2.13 
3 1 O  C HOH 408 ? ? O C HOH 423 ? ? 2.16 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 OD2 C ASP 184 ? ? 1_555 HE1 C HIS 211 ? ? 2_556 1.57 
2 1 O   C HOH 424 ? ? 1_555 O   C HOH 424 ? ? 2_556 2.08 
3 1 NE2 A HIS 205 ? ? 1_555 NE2 A HIS 205 ? ? 2_655 2.10 
4 1 OD2 C ASP 184 ? ? 1_555 CE1 C HIS 211 ? ? 2_556 2.18 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 C5 B DG 8  ? ? N7 B DG 8  ? ? 1.429 1.388 0.041  0.006 N 
2 1 C2 E DT 28 ? ? O2 E DT 28 ? ? 1.161 1.220 -0.059 0.008 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 "O3'" B DA 2  ? ? P     B DT 3  ? ? OP1 B DT 3  ? ? 117.90 110.50 7.40  1.10 Y 
2 1 "O5'" B DG 8  ? ? P     B DG 8  ? ? OP2 B DG 8  ? ? 97.66  105.70 -8.04 0.90 N 
3 1 "O4'" B DG 8  ? ? "C1'" B DG 8  ? ? N9  B DG 8  ? ? 113.50 108.30 5.20  0.30 N 
4 1 "O4'" B DA 11 ? ? "C1'" B DA 11 ? ? N9  B DA 11 ? ? 111.35 108.30 3.05  0.30 N 
5 1 "C3'" D DA 2  ? ? "O3'" D DA 2  ? ? P   D DT 3  ? ? 127.83 119.70 8.13  1.20 Y 
6 1 "O4'" D DT 3  ? ? "C1'" D DT 3  ? ? N1  D DT 3  ? ? 110.97 108.30 2.67  0.30 N 
7 1 "O4'" D DG 8  ? ? "C1'" D DG 8  ? ? N9  D DG 8  ? ? 112.08 108.30 3.78  0.30 N 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    LYS 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     245 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             -84.21 
_pdbx_validate_torsion.psi             48.79 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A HOH 322 ? H HOH . 
2 1 C HOH 426 ? J HOH . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 -x,y,-z         
3 x+1/2,y+1/2,z   
4 -x+1/2,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 165 ? A GLY 1   
2  1 Y 1 A SER 166 ? A SER 2   
3  1 Y 1 A LYS 167 ? A LYS 3   
4  1 Y 1 A LYS 168 ? A LYS 4   
5  1 Y 1 A GLY 260 ? A GLY 96  
6  1 Y 1 A GLY 261 ? A GLY 97  
7  1 Y 1 A LEU 262 ? A LEU 98  
8  1 Y 1 A ALA 263 ? A ALA 99  
9  1 Y 1 A GLU 264 ? A GLU 100 
10 1 Y 1 A ARG 265 ? A ARG 101 
11 1 Y 1 A ARG 266 ? A ARG 102 
12 1 Y 1 A HIS 267 ? A HIS 103 
13 1 Y 1 A PRO 268 ? A PRO 104 
14 1 Y 1 A PRO 269 ? A PRO 105 
15 1 Y 1 A HIS 270 ? A HIS 106 
16 1 Y 1 C GLY 165 ? C GLY 1   
17 1 Y 1 C SER 166 ? C SER 2   
18 1 Y 1 C LYS 167 ? C LYS 3   
19 1 Y 1 C LYS 168 ? C LYS 4   
20 1 Y 1 C GLY 260 ? C GLY 96  
21 1 Y 1 C GLY 261 ? C GLY 97  
22 1 Y 1 C LEU 262 ? C LEU 98  
23 1 Y 1 C ALA 263 ? C ALA 99  
24 1 Y 1 C GLU 264 ? C GLU 100 
25 1 Y 1 C ARG 265 ? C ARG 101 
26 1 Y 1 C ARG 266 ? C ARG 102 
27 1 Y 1 C HIS 267 ? C HIS 103 
28 1 Y 1 C PRO 268 ? C PRO 104 
29 1 Y 1 C PRO 269 ? C PRO 105 
30 1 Y 1 C HIS 270 ? C HIS 106 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
DA  OP3    O  N N 74  
DA  P      P  N N 75  
DA  OP1    O  N N 76  
DA  OP2    O  N N 77  
DA  "O5'"  O  N N 78  
DA  "C5'"  C  N N 79  
DA  "C4'"  C  N R 80  
DA  "O4'"  O  N N 81  
DA  "C3'"  C  N S 82  
DA  "O3'"  O  N N 83  
DA  "C2'"  C  N N 84  
DA  "C1'"  C  N R 85  
DA  N9     N  Y N 86  
DA  C8     C  Y N 87  
DA  N7     N  Y N 88  
DA  C5     C  Y N 89  
DA  C6     C  Y N 90  
DA  N6     N  N N 91  
DA  N1     N  Y N 92  
DA  C2     C  Y N 93  
DA  N3     N  Y N 94  
DA  C4     C  Y N 95  
DA  HOP3   H  N N 96  
DA  HOP2   H  N N 97  
DA  "H5'"  H  N N 98  
DA  "H5''" H  N N 99  
DA  "H4'"  H  N N 100 
DA  "H3'"  H  N N 101 
DA  "HO3'" H  N N 102 
DA  "H2'"  H  N N 103 
DA  "H2''" H  N N 104 
DA  "H1'"  H  N N 105 
DA  H8     H  N N 106 
DA  H61    H  N N 107 
DA  H62    H  N N 108 
DA  H2     H  N N 109 
DC  OP3    O  N N 110 
DC  P      P  N N 111 
DC  OP1    O  N N 112 
DC  OP2    O  N N 113 
DC  "O5'"  O  N N 114 
DC  "C5'"  C  N N 115 
DC  "C4'"  C  N R 116 
DC  "O4'"  O  N N 117 
DC  "C3'"  C  N S 118 
DC  "O3'"  O  N N 119 
DC  "C2'"  C  N N 120 
DC  "C1'"  C  N R 121 
DC  N1     N  N N 122 
DC  C2     C  N N 123 
DC  O2     O  N N 124 
DC  N3     N  N N 125 
DC  C4     C  N N 126 
DC  N4     N  N N 127 
DC  C5     C  N N 128 
DC  C6     C  N N 129 
DC  HOP3   H  N N 130 
DC  HOP2   H  N N 131 
DC  "H5'"  H  N N 132 
DC  "H5''" H  N N 133 
DC  "H4'"  H  N N 134 
DC  "H3'"  H  N N 135 
DC  "HO3'" H  N N 136 
DC  "H2'"  H  N N 137 
DC  "H2''" H  N N 138 
DC  "H1'"  H  N N 139 
DC  H41    H  N N 140 
DC  H42    H  N N 141 
DC  H5     H  N N 142 
DC  H6     H  N N 143 
DG  OP3    O  N N 144 
DG  P      P  N N 145 
DG  OP1    O  N N 146 
DG  OP2    O  N N 147 
DG  "O5'"  O  N N 148 
DG  "C5'"  C  N N 149 
DG  "C4'"  C  N R 150 
DG  "O4'"  O  N N 151 
DG  "C3'"  C  N S 152 
DG  "O3'"  O  N N 153 
DG  "C2'"  C  N N 154 
DG  "C1'"  C  N R 155 
DG  N9     N  Y N 156 
DG  C8     C  Y N 157 
DG  N7     N  Y N 158 
DG  C5     C  Y N 159 
DG  C6     C  N N 160 
DG  O6     O  N N 161 
DG  N1     N  N N 162 
DG  C2     C  N N 163 
DG  N2     N  N N 164 
DG  N3     N  N N 165 
DG  C4     C  Y N 166 
DG  HOP3   H  N N 167 
DG  HOP2   H  N N 168 
DG  "H5'"  H  N N 169 
DG  "H5''" H  N N 170 
DG  "H4'"  H  N N 171 
DG  "H3'"  H  N N 172 
DG  "HO3'" H  N N 173 
DG  "H2'"  H  N N 174 
DG  "H2''" H  N N 175 
DG  "H1'"  H  N N 176 
DG  H8     H  N N 177 
DG  H1     H  N N 178 
DG  H21    H  N N 179 
DG  H22    H  N N 180 
DT  OP3    O  N N 181 
DT  P      P  N N 182 
DT  OP1    O  N N 183 
DT  OP2    O  N N 184 
DT  "O5'"  O  N N 185 
DT  "C5'"  C  N N 186 
DT  "C4'"  C  N R 187 
DT  "O4'"  O  N N 188 
DT  "C3'"  C  N S 189 
DT  "O3'"  O  N N 190 
DT  "C2'"  C  N N 191 
DT  "C1'"  C  N R 192 
DT  N1     N  N N 193 
DT  C2     C  N N 194 
DT  O2     O  N N 195 
DT  N3     N  N N 196 
DT  C4     C  N N 197 
DT  O4     O  N N 198 
DT  C5     C  N N 199 
DT  C7     C  N N 200 
DT  C6     C  N N 201 
DT  HOP3   H  N N 202 
DT  HOP2   H  N N 203 
DT  "H5'"  H  N N 204 
DT  "H5''" H  N N 205 
DT  "H4'"  H  N N 206 
DT  "H3'"  H  N N 207 
DT  "HO3'" H  N N 208 
DT  "H2'"  H  N N 209 
DT  "H2''" H  N N 210 
DT  "H1'"  H  N N 211 
DT  H3     H  N N 212 
DT  H71    H  N N 213 
DT  H72    H  N N 214 
DT  H73    H  N N 215 
DT  H6     H  N N 216 
GLN N      N  N N 217 
GLN CA     C  N S 218 
GLN C      C  N N 219 
GLN O      O  N N 220 
GLN CB     C  N N 221 
GLN CG     C  N N 222 
GLN CD     C  N N 223 
GLN OE1    O  N N 224 
GLN NE2    N  N N 225 
GLN OXT    O  N N 226 
GLN H      H  N N 227 
GLN H2     H  N N 228 
GLN HA     H  N N 229 
GLN HB2    H  N N 230 
GLN HB3    H  N N 231 
GLN HG2    H  N N 232 
GLN HG3    H  N N 233 
GLN HE21   H  N N 234 
GLN HE22   H  N N 235 
GLN HXT    H  N N 236 
GLU N      N  N N 237 
GLU CA     C  N S 238 
GLU C      C  N N 239 
GLU O      O  N N 240 
GLU CB     C  N N 241 
GLU CG     C  N N 242 
GLU CD     C  N N 243 
GLU OE1    O  N N 244 
GLU OE2    O  N N 245 
GLU OXT    O  N N 246 
GLU H      H  N N 247 
GLU H2     H  N N 248 
GLU HA     H  N N 249 
GLU HB2    H  N N 250 
GLU HB3    H  N N 251 
GLU HG2    H  N N 252 
GLU HG3    H  N N 253 
GLU HE2    H  N N 254 
GLU HXT    H  N N 255 
GLY N      N  N N 256 
GLY CA     C  N N 257 
GLY C      C  N N 258 
GLY O      O  N N 259 
GLY OXT    O  N N 260 
GLY H      H  N N 261 
GLY H2     H  N N 262 
GLY HA2    H  N N 263 
GLY HA3    H  N N 264 
GLY HXT    H  N N 265 
HIS N      N  N N 266 
HIS CA     C  N S 267 
HIS C      C  N N 268 
HIS O      O  N N 269 
HIS CB     C  N N 270 
HIS CG     C  Y N 271 
HIS ND1    N  Y N 272 
HIS CD2    C  Y N 273 
HIS CE1    C  Y N 274 
HIS NE2    N  Y N 275 
HIS OXT    O  N N 276 
HIS H      H  N N 277 
HIS H2     H  N N 278 
HIS HA     H  N N 279 
HIS HB2    H  N N 280 
HIS HB3    H  N N 281 
HIS HD1    H  N N 282 
HIS HD2    H  N N 283 
HIS HE1    H  N N 284 
HIS HE2    H  N N 285 
HIS HXT    H  N N 286 
HOH O      O  N N 287 
HOH H1     H  N N 288 
HOH H2     H  N N 289 
ILE N      N  N N 290 
ILE CA     C  N S 291 
ILE C      C  N N 292 
ILE O      O  N N 293 
ILE CB     C  N S 294 
ILE CG1    C  N N 295 
ILE CG2    C  N N 296 
ILE CD1    C  N N 297 
ILE OXT    O  N N 298 
ILE H      H  N N 299 
ILE H2     H  N N 300 
ILE HA     H  N N 301 
ILE HB     H  N N 302 
ILE HG12   H  N N 303 
ILE HG13   H  N N 304 
ILE HG21   H  N N 305 
ILE HG22   H  N N 306 
ILE HG23   H  N N 307 
ILE HD11   H  N N 308 
ILE HD12   H  N N 309 
ILE HD13   H  N N 310 
ILE HXT    H  N N 311 
LEU N      N  N N 312 
LEU CA     C  N S 313 
LEU C      C  N N 314 
LEU O      O  N N 315 
LEU CB     C  N N 316 
LEU CG     C  N N 317 
LEU CD1    C  N N 318 
LEU CD2    C  N N 319 
LEU OXT    O  N N 320 
LEU H      H  N N 321 
LEU H2     H  N N 322 
LEU HA     H  N N 323 
LEU HB2    H  N N 324 
LEU HB3    H  N N 325 
LEU HG     H  N N 326 
LEU HD11   H  N N 327 
LEU HD12   H  N N 328 
LEU HD13   H  N N 329 
LEU HD21   H  N N 330 
LEU HD22   H  N N 331 
LEU HD23   H  N N 332 
LEU HXT    H  N N 333 
LYS N      N  N N 334 
LYS CA     C  N S 335 
LYS C      C  N N 336 
LYS O      O  N N 337 
LYS CB     C  N N 338 
LYS CG     C  N N 339 
LYS CD     C  N N 340 
LYS CE     C  N N 341 
LYS NZ     N  N N 342 
LYS OXT    O  N N 343 
LYS H      H  N N 344 
LYS H2     H  N N 345 
LYS HA     H  N N 346 
LYS HB2    H  N N 347 
LYS HB3    H  N N 348 
LYS HG2    H  N N 349 
LYS HG3    H  N N 350 
LYS HD2    H  N N 351 
LYS HD3    H  N N 352 
LYS HE2    H  N N 353 
LYS HE3    H  N N 354 
LYS HZ1    H  N N 355 
LYS HZ2    H  N N 356 
LYS HZ3    H  N N 357 
LYS HXT    H  N N 358 
MET N      N  N N 359 
MET CA     C  N S 360 
MET C      C  N N 361 
MET O      O  N N 362 
MET CB     C  N N 363 
MET CG     C  N N 364 
MET SD     S  N N 365 
MET CE     C  N N 366 
MET OXT    O  N N 367 
MET H      H  N N 368 
MET H2     H  N N 369 
MET HA     H  N N 370 
MET HB2    H  N N 371 
MET HB3    H  N N 372 
MET HG2    H  N N 373 
MET HG3    H  N N 374 
MET HE1    H  N N 375 
MET HE2    H  N N 376 
MET HE3    H  N N 377 
MET HXT    H  N N 378 
PHE N      N  N N 379 
PHE CA     C  N S 380 
PHE C      C  N N 381 
PHE O      O  N N 382 
PHE CB     C  N N 383 
PHE CG     C  Y N 384 
PHE CD1    C  Y N 385 
PHE CD2    C  Y N 386 
PHE CE1    C  Y N 387 
PHE CE2    C  Y N 388 
PHE CZ     C  Y N 389 
PHE OXT    O  N N 390 
PHE H      H  N N 391 
PHE H2     H  N N 392 
PHE HA     H  N N 393 
PHE HB2    H  N N 394 
PHE HB3    H  N N 395 
PHE HD1    H  N N 396 
PHE HD2    H  N N 397 
PHE HE1    H  N N 398 
PHE HE2    H  N N 399 
PHE HZ     H  N N 400 
PHE HXT    H  N N 401 
PRO N      N  N N 402 
PRO CA     C  N S 403 
PRO C      C  N N 404 
PRO O      O  N N 405 
PRO CB     C  N N 406 
PRO CG     C  N N 407 
PRO CD     C  N N 408 
PRO OXT    O  N N 409 
PRO H      H  N N 410 
PRO HA     H  N N 411 
PRO HB2    H  N N 412 
PRO HB3    H  N N 413 
PRO HG2    H  N N 414 
PRO HG3    H  N N 415 
PRO HD2    H  N N 416 
PRO HD3    H  N N 417 
PRO HXT    H  N N 418 
SER N      N  N N 419 
SER CA     C  N S 420 
SER C      C  N N 421 
SER O      O  N N 422 
SER CB     C  N N 423 
SER OG     O  N N 424 
SER OXT    O  N N 425 
SER H      H  N N 426 
SER H2     H  N N 427 
SER HA     H  N N 428 
SER HB2    H  N N 429 
SER HB3    H  N N 430 
SER HG     H  N N 431 
SER HXT    H  N N 432 
THR N      N  N N 433 
THR CA     C  N S 434 
THR C      C  N N 435 
THR O      O  N N 436 
THR CB     C  N R 437 
THR OG1    O  N N 438 
THR CG2    C  N N 439 
THR OXT    O  N N 440 
THR H      H  N N 441 
THR H2     H  N N 442 
THR HA     H  N N 443 
THR HB     H  N N 444 
THR HG1    H  N N 445 
THR HG21   H  N N 446 
THR HG22   H  N N 447 
THR HG23   H  N N 448 
THR HXT    H  N N 449 
TRP N      N  N N 450 
TRP CA     C  N S 451 
TRP C      C  N N 452 
TRP O      O  N N 453 
TRP CB     C  N N 454 
TRP CG     C  Y N 455 
TRP CD1    C  Y N 456 
TRP CD2    C  Y N 457 
TRP NE1    N  Y N 458 
TRP CE2    C  Y N 459 
TRP CE3    C  Y N 460 
TRP CZ2    C  Y N 461 
TRP CZ3    C  Y N 462 
TRP CH2    C  Y N 463 
TRP OXT    O  N N 464 
TRP H      H  N N 465 
TRP H2     H  N N 466 
TRP HA     H  N N 467 
TRP HB2    H  N N 468 
TRP HB3    H  N N 469 
TRP HD1    H  N N 470 
TRP HE1    H  N N 471 
TRP HE3    H  N N 472 
TRP HZ2    H  N N 473 
TRP HZ3    H  N N 474 
TRP HH2    H  N N 475 
TRP HXT    H  N N 476 
TYR N      N  N N 477 
TYR CA     C  N S 478 
TYR C      C  N N 479 
TYR O      O  N N 480 
TYR CB     C  N N 481 
TYR CG     C  Y N 482 
TYR CD1    C  Y N 483 
TYR CD2    C  Y N 484 
TYR CE1    C  Y N 485 
TYR CE2    C  Y N 486 
TYR CZ     C  Y N 487 
TYR OH     O  N N 488 
TYR OXT    O  N N 489 
TYR H      H  N N 490 
TYR H2     H  N N 491 
TYR HA     H  N N 492 
TYR HB2    H  N N 493 
TYR HB3    H  N N 494 
TYR HD1    H  N N 495 
TYR HD2    H  N N 496 
TYR HE1    H  N N 497 
TYR HE2    H  N N 498 
TYR HH     H  N N 499 
TYR HXT    H  N N 500 
VAL N      N  N N 501 
VAL CA     C  N S 502 
VAL C      C  N N 503 
VAL O      O  N N 504 
VAL CB     C  N N 505 
VAL CG1    C  N N 506 
VAL CG2    C  N N 507 
VAL OXT    O  N N 508 
VAL H      H  N N 509 
VAL H2     H  N N 510 
VAL HA     H  N N 511 
VAL HB     H  N N 512 
VAL HG11   H  N N 513 
VAL HG12   H  N N 514 
VAL HG13   H  N N 515 
VAL HG21   H  N N 516 
VAL HG22   H  N N 517 
VAL HG23   H  N N 518 
VAL HXT    H  N N 519 
ZN  ZN     ZN N N 520 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
DA  OP3   P      sing N N 70  
DA  OP3   HOP3   sing N N 71  
DA  P     OP1    doub N N 72  
DA  P     OP2    sing N N 73  
DA  P     "O5'"  sing N N 74  
DA  OP2   HOP2   sing N N 75  
DA  "O5'" "C5'"  sing N N 76  
DA  "C5'" "C4'"  sing N N 77  
DA  "C5'" "H5'"  sing N N 78  
DA  "C5'" "H5''" sing N N 79  
DA  "C4'" "O4'"  sing N N 80  
DA  "C4'" "C3'"  sing N N 81  
DA  "C4'" "H4'"  sing N N 82  
DA  "O4'" "C1'"  sing N N 83  
DA  "C3'" "O3'"  sing N N 84  
DA  "C3'" "C2'"  sing N N 85  
DA  "C3'" "H3'"  sing N N 86  
DA  "O3'" "HO3'" sing N N 87  
DA  "C2'" "C1'"  sing N N 88  
DA  "C2'" "H2'"  sing N N 89  
DA  "C2'" "H2''" sing N N 90  
DA  "C1'" N9     sing N N 91  
DA  "C1'" "H1'"  sing N N 92  
DA  N9    C8     sing Y N 93  
DA  N9    C4     sing Y N 94  
DA  C8    N7     doub Y N 95  
DA  C8    H8     sing N N 96  
DA  N7    C5     sing Y N 97  
DA  C5    C6     sing Y N 98  
DA  C5    C4     doub Y N 99  
DA  C6    N6     sing N N 100 
DA  C6    N1     doub Y N 101 
DA  N6    H61    sing N N 102 
DA  N6    H62    sing N N 103 
DA  N1    C2     sing Y N 104 
DA  C2    N3     doub Y N 105 
DA  C2    H2     sing N N 106 
DA  N3    C4     sing Y N 107 
DC  OP3   P      sing N N 108 
DC  OP3   HOP3   sing N N 109 
DC  P     OP1    doub N N 110 
DC  P     OP2    sing N N 111 
DC  P     "O5'"  sing N N 112 
DC  OP2   HOP2   sing N N 113 
DC  "O5'" "C5'"  sing N N 114 
DC  "C5'" "C4'"  sing N N 115 
DC  "C5'" "H5'"  sing N N 116 
DC  "C5'" "H5''" sing N N 117 
DC  "C4'" "O4'"  sing N N 118 
DC  "C4'" "C3'"  sing N N 119 
DC  "C4'" "H4'"  sing N N 120 
DC  "O4'" "C1'"  sing N N 121 
DC  "C3'" "O3'"  sing N N 122 
DC  "C3'" "C2'"  sing N N 123 
DC  "C3'" "H3'"  sing N N 124 
DC  "O3'" "HO3'" sing N N 125 
DC  "C2'" "C1'"  sing N N 126 
DC  "C2'" "H2'"  sing N N 127 
DC  "C2'" "H2''" sing N N 128 
DC  "C1'" N1     sing N N 129 
DC  "C1'" "H1'"  sing N N 130 
DC  N1    C2     sing N N 131 
DC  N1    C6     sing N N 132 
DC  C2    O2     doub N N 133 
DC  C2    N3     sing N N 134 
DC  N3    C4     doub N N 135 
DC  C4    N4     sing N N 136 
DC  C4    C5     sing N N 137 
DC  N4    H41    sing N N 138 
DC  N4    H42    sing N N 139 
DC  C5    C6     doub N N 140 
DC  C5    H5     sing N N 141 
DC  C6    H6     sing N N 142 
DG  OP3   P      sing N N 143 
DG  OP3   HOP3   sing N N 144 
DG  P     OP1    doub N N 145 
DG  P     OP2    sing N N 146 
DG  P     "O5'"  sing N N 147 
DG  OP2   HOP2   sing N N 148 
DG  "O5'" "C5'"  sing N N 149 
DG  "C5'" "C4'"  sing N N 150 
DG  "C5'" "H5'"  sing N N 151 
DG  "C5'" "H5''" sing N N 152 
DG  "C4'" "O4'"  sing N N 153 
DG  "C4'" "C3'"  sing N N 154 
DG  "C4'" "H4'"  sing N N 155 
DG  "O4'" "C1'"  sing N N 156 
DG  "C3'" "O3'"  sing N N 157 
DG  "C3'" "C2'"  sing N N 158 
DG  "C3'" "H3'"  sing N N 159 
DG  "O3'" "HO3'" sing N N 160 
DG  "C2'" "C1'"  sing N N 161 
DG  "C2'" "H2'"  sing N N 162 
DG  "C2'" "H2''" sing N N 163 
DG  "C1'" N9     sing N N 164 
DG  "C1'" "H1'"  sing N N 165 
DG  N9    C8     sing Y N 166 
DG  N9    C4     sing Y N 167 
DG  C8    N7     doub Y N 168 
DG  C8    H8     sing N N 169 
DG  N7    C5     sing Y N 170 
DG  C5    C6     sing N N 171 
DG  C5    C4     doub Y N 172 
DG  C6    O6     doub N N 173 
DG  C6    N1     sing N N 174 
DG  N1    C2     sing N N 175 
DG  N1    H1     sing N N 176 
DG  C2    N2     sing N N 177 
DG  C2    N3     doub N N 178 
DG  N2    H21    sing N N 179 
DG  N2    H22    sing N N 180 
DG  N3    C4     sing N N 181 
DT  OP3   P      sing N N 182 
DT  OP3   HOP3   sing N N 183 
DT  P     OP1    doub N N 184 
DT  P     OP2    sing N N 185 
DT  P     "O5'"  sing N N 186 
DT  OP2   HOP2   sing N N 187 
DT  "O5'" "C5'"  sing N N 188 
DT  "C5'" "C4'"  sing N N 189 
DT  "C5'" "H5'"  sing N N 190 
DT  "C5'" "H5''" sing N N 191 
DT  "C4'" "O4'"  sing N N 192 
DT  "C4'" "C3'"  sing N N 193 
DT  "C4'" "H4'"  sing N N 194 
DT  "O4'" "C1'"  sing N N 195 
DT  "C3'" "O3'"  sing N N 196 
DT  "C3'" "C2'"  sing N N 197 
DT  "C3'" "H3'"  sing N N 198 
DT  "O3'" "HO3'" sing N N 199 
DT  "C2'" "C1'"  sing N N 200 
DT  "C2'" "H2'"  sing N N 201 
DT  "C2'" "H2''" sing N N 202 
DT  "C1'" N1     sing N N 203 
DT  "C1'" "H1'"  sing N N 204 
DT  N1    C2     sing N N 205 
DT  N1    C6     sing N N 206 
DT  C2    O2     doub N N 207 
DT  C2    N3     sing N N 208 
DT  N3    C4     sing N N 209 
DT  N3    H3     sing N N 210 
DT  C4    O4     doub N N 211 
DT  C4    C5     sing N N 212 
DT  C5    C7     sing N N 213 
DT  C5    C6     doub N N 214 
DT  C7    H71    sing N N 215 
DT  C7    H72    sing N N 216 
DT  C7    H73    sing N N 217 
DT  C6    H6     sing N N 218 
GLN N     CA     sing N N 219 
GLN N     H      sing N N 220 
GLN N     H2     sing N N 221 
GLN CA    C      sing N N 222 
GLN CA    CB     sing N N 223 
GLN CA    HA     sing N N 224 
GLN C     O      doub N N 225 
GLN C     OXT    sing N N 226 
GLN CB    CG     sing N N 227 
GLN CB    HB2    sing N N 228 
GLN CB    HB3    sing N N 229 
GLN CG    CD     sing N N 230 
GLN CG    HG2    sing N N 231 
GLN CG    HG3    sing N N 232 
GLN CD    OE1    doub N N 233 
GLN CD    NE2    sing N N 234 
GLN NE2   HE21   sing N N 235 
GLN NE2   HE22   sing N N 236 
GLN OXT   HXT    sing N N 237 
GLU N     CA     sing N N 238 
GLU N     H      sing N N 239 
GLU N     H2     sing N N 240 
GLU CA    C      sing N N 241 
GLU CA    CB     sing N N 242 
GLU CA    HA     sing N N 243 
GLU C     O      doub N N 244 
GLU C     OXT    sing N N 245 
GLU CB    CG     sing N N 246 
GLU CB    HB2    sing N N 247 
GLU CB    HB3    sing N N 248 
GLU CG    CD     sing N N 249 
GLU CG    HG2    sing N N 250 
GLU CG    HG3    sing N N 251 
GLU CD    OE1    doub N N 252 
GLU CD    OE2    sing N N 253 
GLU OE2   HE2    sing N N 254 
GLU OXT   HXT    sing N N 255 
GLY N     CA     sing N N 256 
GLY N     H      sing N N 257 
GLY N     H2     sing N N 258 
GLY CA    C      sing N N 259 
GLY CA    HA2    sing N N 260 
GLY CA    HA3    sing N N 261 
GLY C     O      doub N N 262 
GLY C     OXT    sing N N 263 
GLY OXT   HXT    sing N N 264 
HIS N     CA     sing N N 265 
HIS N     H      sing N N 266 
HIS N     H2     sing N N 267 
HIS CA    C      sing N N 268 
HIS CA    CB     sing N N 269 
HIS CA    HA     sing N N 270 
HIS C     O      doub N N 271 
HIS C     OXT    sing N N 272 
HIS CB    CG     sing N N 273 
HIS CB    HB2    sing N N 274 
HIS CB    HB3    sing N N 275 
HIS CG    ND1    sing Y N 276 
HIS CG    CD2    doub Y N 277 
HIS ND1   CE1    doub Y N 278 
HIS ND1   HD1    sing N N 279 
HIS CD2   NE2    sing Y N 280 
HIS CD2   HD2    sing N N 281 
HIS CE1   NE2    sing Y N 282 
HIS CE1   HE1    sing N N 283 
HIS NE2   HE2    sing N N 284 
HIS OXT   HXT    sing N N 285 
HOH O     H1     sing N N 286 
HOH O     H2     sing N N 287 
ILE N     CA     sing N N 288 
ILE N     H      sing N N 289 
ILE N     H2     sing N N 290 
ILE CA    C      sing N N 291 
ILE CA    CB     sing N N 292 
ILE CA    HA     sing N N 293 
ILE C     O      doub N N 294 
ILE C     OXT    sing N N 295 
ILE CB    CG1    sing N N 296 
ILE CB    CG2    sing N N 297 
ILE CB    HB     sing N N 298 
ILE CG1   CD1    sing N N 299 
ILE CG1   HG12   sing N N 300 
ILE CG1   HG13   sing N N 301 
ILE CG2   HG21   sing N N 302 
ILE CG2   HG22   sing N N 303 
ILE CG2   HG23   sing N N 304 
ILE CD1   HD11   sing N N 305 
ILE CD1   HD12   sing N N 306 
ILE CD1   HD13   sing N N 307 
ILE OXT   HXT    sing N N 308 
LEU N     CA     sing N N 309 
LEU N     H      sing N N 310 
LEU N     H2     sing N N 311 
LEU CA    C      sing N N 312 
LEU CA    CB     sing N N 313 
LEU CA    HA     sing N N 314 
LEU C     O      doub N N 315 
LEU C     OXT    sing N N 316 
LEU CB    CG     sing N N 317 
LEU CB    HB2    sing N N 318 
LEU CB    HB3    sing N N 319 
LEU CG    CD1    sing N N 320 
LEU CG    CD2    sing N N 321 
LEU CG    HG     sing N N 322 
LEU CD1   HD11   sing N N 323 
LEU CD1   HD12   sing N N 324 
LEU CD1   HD13   sing N N 325 
LEU CD2   HD21   sing N N 326 
LEU CD2   HD22   sing N N 327 
LEU CD2   HD23   sing N N 328 
LEU OXT   HXT    sing N N 329 
LYS N     CA     sing N N 330 
LYS N     H      sing N N 331 
LYS N     H2     sing N N 332 
LYS CA    C      sing N N 333 
LYS CA    CB     sing N N 334 
LYS CA    HA     sing N N 335 
LYS C     O      doub N N 336 
LYS C     OXT    sing N N 337 
LYS CB    CG     sing N N 338 
LYS CB    HB2    sing N N 339 
LYS CB    HB3    sing N N 340 
LYS CG    CD     sing N N 341 
LYS CG    HG2    sing N N 342 
LYS CG    HG3    sing N N 343 
LYS CD    CE     sing N N 344 
LYS CD    HD2    sing N N 345 
LYS CD    HD3    sing N N 346 
LYS CE    NZ     sing N N 347 
LYS CE    HE2    sing N N 348 
LYS CE    HE3    sing N N 349 
LYS NZ    HZ1    sing N N 350 
LYS NZ    HZ2    sing N N 351 
LYS NZ    HZ3    sing N N 352 
LYS OXT   HXT    sing N N 353 
MET N     CA     sing N N 354 
MET N     H      sing N N 355 
MET N     H2     sing N N 356 
MET CA    C      sing N N 357 
MET CA    CB     sing N N 358 
MET CA    HA     sing N N 359 
MET C     O      doub N N 360 
MET C     OXT    sing N N 361 
MET CB    CG     sing N N 362 
MET CB    HB2    sing N N 363 
MET CB    HB3    sing N N 364 
MET CG    SD     sing N N 365 
MET CG    HG2    sing N N 366 
MET CG    HG3    sing N N 367 
MET SD    CE     sing N N 368 
MET CE    HE1    sing N N 369 
MET CE    HE2    sing N N 370 
MET CE    HE3    sing N N 371 
MET OXT   HXT    sing N N 372 
PHE N     CA     sing N N 373 
PHE N     H      sing N N 374 
PHE N     H2     sing N N 375 
PHE CA    C      sing N N 376 
PHE CA    CB     sing N N 377 
PHE CA    HA     sing N N 378 
PHE C     O      doub N N 379 
PHE C     OXT    sing N N 380 
PHE CB    CG     sing N N 381 
PHE CB    HB2    sing N N 382 
PHE CB    HB3    sing N N 383 
PHE CG    CD1    doub Y N 384 
PHE CG    CD2    sing Y N 385 
PHE CD1   CE1    sing Y N 386 
PHE CD1   HD1    sing N N 387 
PHE CD2   CE2    doub Y N 388 
PHE CD2   HD2    sing N N 389 
PHE CE1   CZ     doub Y N 390 
PHE CE1   HE1    sing N N 391 
PHE CE2   CZ     sing Y N 392 
PHE CE2   HE2    sing N N 393 
PHE CZ    HZ     sing N N 394 
PHE OXT   HXT    sing N N 395 
PRO N     CA     sing N N 396 
PRO N     CD     sing N N 397 
PRO N     H      sing N N 398 
PRO CA    C      sing N N 399 
PRO CA    CB     sing N N 400 
PRO CA    HA     sing N N 401 
PRO C     O      doub N N 402 
PRO C     OXT    sing N N 403 
PRO CB    CG     sing N N 404 
PRO CB    HB2    sing N N 405 
PRO CB    HB3    sing N N 406 
PRO CG    CD     sing N N 407 
PRO CG    HG2    sing N N 408 
PRO CG    HG3    sing N N 409 
PRO CD    HD2    sing N N 410 
PRO CD    HD3    sing N N 411 
PRO OXT   HXT    sing N N 412 
SER N     CA     sing N N 413 
SER N     H      sing N N 414 
SER N     H2     sing N N 415 
SER CA    C      sing N N 416 
SER CA    CB     sing N N 417 
SER CA    HA     sing N N 418 
SER C     O      doub N N 419 
SER C     OXT    sing N N 420 
SER CB    OG     sing N N 421 
SER CB    HB2    sing N N 422 
SER CB    HB3    sing N N 423 
SER OG    HG     sing N N 424 
SER OXT   HXT    sing N N 425 
THR N     CA     sing N N 426 
THR N     H      sing N N 427 
THR N     H2     sing N N 428 
THR CA    C      sing N N 429 
THR CA    CB     sing N N 430 
THR CA    HA     sing N N 431 
THR C     O      doub N N 432 
THR C     OXT    sing N N 433 
THR CB    OG1    sing N N 434 
THR CB    CG2    sing N N 435 
THR CB    HB     sing N N 436 
THR OG1   HG1    sing N N 437 
THR CG2   HG21   sing N N 438 
THR CG2   HG22   sing N N 439 
THR CG2   HG23   sing N N 440 
THR OXT   HXT    sing N N 441 
TRP N     CA     sing N N 442 
TRP N     H      sing N N 443 
TRP N     H2     sing N N 444 
TRP CA    C      sing N N 445 
TRP CA    CB     sing N N 446 
TRP CA    HA     sing N N 447 
TRP C     O      doub N N 448 
TRP C     OXT    sing N N 449 
TRP CB    CG     sing N N 450 
TRP CB    HB2    sing N N 451 
TRP CB    HB3    sing N N 452 
TRP CG    CD1    doub Y N 453 
TRP CG    CD2    sing Y N 454 
TRP CD1   NE1    sing Y N 455 
TRP CD1   HD1    sing N N 456 
TRP CD2   CE2    doub Y N 457 
TRP CD2   CE3    sing Y N 458 
TRP NE1   CE2    sing Y N 459 
TRP NE1   HE1    sing N N 460 
TRP CE2   CZ2    sing Y N 461 
TRP CE3   CZ3    doub Y N 462 
TRP CE3   HE3    sing N N 463 
TRP CZ2   CH2    doub Y N 464 
TRP CZ2   HZ2    sing N N 465 
TRP CZ3   CH2    sing Y N 466 
TRP CZ3   HZ3    sing N N 467 
TRP CH2   HH2    sing N N 468 
TRP OXT   HXT    sing N N 469 
TYR N     CA     sing N N 470 
TYR N     H      sing N N 471 
TYR N     H2     sing N N 472 
TYR CA    C      sing N N 473 
TYR CA    CB     sing N N 474 
TYR CA    HA     sing N N 475 
TYR C     O      doub N N 476 
TYR C     OXT    sing N N 477 
TYR CB    CG     sing N N 478 
TYR CB    HB2    sing N N 479 
TYR CB    HB3    sing N N 480 
TYR CG    CD1    doub Y N 481 
TYR CG    CD2    sing Y N 482 
TYR CD1   CE1    sing Y N 483 
TYR CD1   HD1    sing N N 484 
TYR CD2   CE2    doub Y N 485 
TYR CD2   HD2    sing N N 486 
TYR CE1   CZ     doub Y N 487 
TYR CE1   HE1    sing N N 488 
TYR CE2   CZ     sing Y N 489 
TYR CE2   HE2    sing N N 490 
TYR CZ    OH     sing N N 491 
TYR OH    HH     sing N N 492 
TYR OXT   HXT    sing N N 493 
VAL N     CA     sing N N 494 
VAL N     H      sing N N 495 
VAL N     H2     sing N N 496 
VAL CA    C      sing N N 497 
VAL CA    CB     sing N N 498 
VAL CA    HA     sing N N 499 
VAL C     O      doub N N 500 
VAL C     OXT    sing N N 501 
VAL CB    CG1    sing N N 502 
VAL CB    CG2    sing N N 503 
VAL CB    HB     sing N N 504 
VAL CG1   HG11   sing N N 505 
VAL CG1   HG12   sing N N 506 
VAL CG1   HG13   sing N N 507 
VAL CG2   HG21   sing N N 508 
VAL CG2   HG22   sing N N 509 
VAL CG2   HG23   sing N N 510 
VAL OXT   HXT    sing N N 511 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9CMB 'double helix'        
9CMB 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 B DA 2  1_555 E DT 16 1_555 0.756  0.180  0.614  2.209   -9.081  11.716 1  B_DA2:DT32_E  B 2  ? E 32 ? 20 1 
1 B DT 3  1_555 E DA 15 1_555 0.619  -0.173 0.120  9.301   -1.195  6.693  2  B_DT3:DA31_E  B 3  ? E 31 ? 20 1 
1 B DA 4  1_555 E DT 14 1_555 0.275  0.296  0.338  7.393   -15.029 4.595  3  B_DA4:DT30_E  B 4  ? E 30 ? 20 1 
1 B DA 5  1_555 E DT 13 1_555 0.296  -0.281 0.095  3.973   -20.063 3.613  4  B_DA5:DT29_E  B 5  ? E 29 ? 20 1 
1 B DA 6  1_555 E DT 12 1_555 0.228  -0.098 -0.109 -1.653  -13.368 3.726  5  B_DA6:DT28_E  B 6  ? E 28 ? 20 1 
1 B DA 7  1_555 E DT 11 1_555 0.054  -0.290 0.037  -7.625  -2.517  -0.591 6  B_DA7:DT27_E  B 7  ? E 27 ? 20 1 
1 B DG 8  1_555 E DC 10 1_555 -0.642 0.005  1.310  24.977  11.316  1.513  7  B_DG8:DC26_E  B 8  ? E 26 ? 19 1 
1 B DG 9  1_555 E DC 9  1_555 -0.327 -0.198 0.154  9.048   -8.043  0.719  8  B_DG9:DC25_E  B 9  ? E 25 ? 19 1 
1 B DA 10 1_555 E DT 8  1_555 0.065  -0.282 -0.075 10.570  -11.719 3.662  9  B_DA10:DT24_E B 10 ? E 24 ? 20 1 
1 B DA 11 1_555 E DT 7  1_555 -0.619 -0.149 -0.289 9.243   -20.634 -5.020 10 B_DA11:DT23_E B 11 ? E 23 ? 20 1 
1 B DG 12 1_555 E DC 6  1_555 -0.307 -0.192 0.078  -6.090  -16.160 1.614  11 B_DG12:DC22_E B 12 ? E 22 ? 19 1 
1 B DT 13 1_555 E DA 5  1_555 -0.119 -0.112 0.381  -8.212  -11.075 4.728  12 B_DT13:DA21_E B 13 ? E 21 ? 20 1 
1 B DG 14 1_555 E DC 4  1_555 -0.150 -2.369 -1.295 15.951  -4.202  89.235 13 B_DG14:DC20_E B 14 ? E 20 ? ?  ? 
1 B DG 15 1_555 E DC 3  1_555 -0.261 0.078  0.007  -0.106  -10.868 5.600  14 B_DG15:DC19_E B 15 ? E 19 ? 19 1 
1 B DG 16 1_555 E DC 2  1_555 -0.326 -0.061 -0.217 3.330   -11.891 2.692  15 B_DG16:DC18_E B 16 ? E 18 ? 19 1 
1 D DA 2  1_555 F DT 16 1_555 1.447  0.224  0.799  2.760   -6.276  11.546 16 D_DA2:DT32_F  D 2  ? F 32 ? ?  ? 
1 D DT 3  1_555 F DA 15 1_555 -0.080 -0.279 0.224  10.905  -8.537  1.459  17 D_DT3:DA31_F  D 3  ? F 31 ? 20 1 
1 D DA 4  1_555 F DT 14 1_555 -0.889 -0.067 0.285  5.360   -9.201  -4.014 18 D_DA4:DT30_F  D 4  ? F 30 ? 20 1 
1 D DA 5  1_555 F DT 13 1_555 0.205  -0.224 0.360  3.633   -15.263 -0.100 19 D_DA5:DT29_F  D 5  ? F 29 ? 20 1 
1 D DA 6  1_555 F DT 12 1_555 0.251  -0.165 0.219  1.882   -12.904 4.479  20 D_DA6:DT28_F  D 6  ? F 28 ? 20 1 
1 D DA 7  1_555 F DT 11 1_555 -0.025 -0.359 0.139  -8.351  -6.486  3.595  21 D_DA7:DT27_F  D 7  ? F 27 ? 20 1 
1 D DG 8  1_555 F DC 10 1_555 -0.224 -0.303 0.213  9.796   3.411   0.665  22 D_DG8:DC26_F  D 8  ? F 26 ? 19 1 
1 D DG 9  1_555 F DC 9  1_555 -0.353 -0.154 0.082  7.898   -3.105  3.183  23 D_DG9:DC25_F  D 9  ? F 25 ? 19 1 
1 D DA 10 1_555 F DT 8  1_555 0.194  -0.123 0.180  7.744   -10.034 3.208  24 D_DA10:DT24_F D 10 ? F 24 ? 20 1 
1 D DA 11 1_555 F DT 7  1_555 0.330  -0.117 0.299  7.236   -14.098 7.018  25 D_DA11:DT23_F D 11 ? F 23 ? 20 1 
1 D DG 12 1_555 F DC 6  1_555 -0.246 -0.088 -0.235 -11.610 -15.551 0.869  26 D_DG12:DC22_F D 12 ? F 22 ? 19 1 
1 D DT 13 1_555 F DA 5  1_555 -0.304 0.070  0.194  -9.530  -10.792 4.759  27 D_DT13:DA21_F D 13 ? F 21 ? 20 1 
1 D DG 14 1_555 F DC 4  1_555 0.350  -2.911 -0.360 18.372  9.359   93.087 28 D_DG14:DC20_F D 14 ? F 20 ? ?  ? 
1 D DG 15 1_555 F DC 3  1_555 0.617  0.197  -0.037 7.743   -19.508 9.316  29 D_DG15:DC19_F D 15 ? F 19 ? 19 1 
1 D DG 16 1_555 F DC 2  1_555 -0.165 -0.072 -0.267 3.091   -13.688 4.923  30 D_DG16:DC18_F D 16 ? F 18 ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 B DA 2  1_555 E DT 16 1_555 B DT 3  1_555 E DA 15 1_555 -0.135 -0.433 3.132  2.116    0.658   28.842   -1.007 0.718  3.104  
1.318   -4.241  28.926   1  BB_DA2DT3:DA31DT32_EE   B 2  ? E 32 ? B 3  ? E 31 ? 
1 B DT 3  1_555 E DA 15 1_555 B DA 4  1_555 E DT 14 1_555 -0.360 0.596  3.429  -0.666   -7.023  38.784   1.744  0.453  3.281  
-10.471 0.992   39.396   2  BB_DT3DA4:DT30DA31_EE   B 3  ? E 31 ? B 4  ? E 30 ? 
1 B DA 4  1_555 E DT 14 1_555 B DA 5  1_555 E DT 13 1_555 0.041  -0.630 3.273  2.231    -0.849  35.834   -0.900 0.253  3.283  
-1.378  -3.620  35.910   3  BB_DA4DA5:DT29DT30_EE   B 4  ? E 30 ? B 5  ? E 29 ? 
1 B DA 5  1_555 E DT 13 1_555 B DA 6  1_555 E DT 12 1_555 0.072  -0.504 3.384  -0.061   0.616   36.749   -0.887 -0.123 3.375  
0.977   0.096   36.754   4  BB_DA5DA6:DT28DT29_EE   B 5  ? E 29 ? B 6  ? E 28 ? 
1 B DA 6  1_555 E DT 12 1_555 B DA 7  1_555 E DT 11 1_555 0.041  -0.828 3.472  -2.556   1.046   29.933   -1.824 -0.634 3.427  
2.019   4.935   30.057   5  BB_DA6DA7:DT27DT28_EE   B 6  ? E 28 ? B 7  ? E 27 ? 
1 B DA 7  1_555 E DT 11 1_555 B DG 8  1_555 E DC 10 1_555 0.727  -0.369 2.488  -8.486   2.765   25.225   -1.315 -3.160 2.086  
6.093   18.699  26.733   6  BB_DA7DG8:DC26DT27_EE   B 7  ? E 27 ? B 8  ? E 26 ? 
1 B DG 8  1_555 E DC 10 1_555 B DG 9  1_555 E DC 9  1_555 -1.062 0.053  4.001  5.819    7.912   34.910   -1.249 2.691  3.706  
12.876  -9.471  36.224   7  BB_DG8DG9:DC25DC26_EE   B 8  ? E 26 ? B 9  ? E 25 ? 
1 B DG 9  1_555 E DC 9  1_555 B DA 10 1_555 E DT 8  1_555 0.021  -0.146 3.361  1.752    7.513   29.504   -1.812 0.318  3.222  
14.444  -3.368  30.474   8  BB_DG9DA10:DT24DC25_EE  B 9  ? E 25 ? B 10 ? E 24 ? 
1 B DA 10 1_555 E DT 8  1_555 B DA 11 1_555 E DT 7  1_555 -0.384 0.108  3.149  1.672    3.536   30.812   -0.450 1.026  3.117  
6.621   -3.131  31.054   9  BB_DA10DA11:DT23DT24_EE B 10 ? E 24 ? B 11 ? E 23 ? 
1 B DA 11 1_555 E DT 7  1_555 B DG 12 1_555 E DC 6  1_555 0.343  -1.004 3.673  -5.118   6.261   42.317   -2.046 -1.021 3.436  
8.578   7.013   43.048   10 BB_DA11DG12:DC22DT23_EE B 11 ? E 23 ? B 12 ? E 22 ? 
1 B DG 12 1_555 E DC 6  1_555 B DT 13 1_555 E DA 5  1_555 -0.943 -0.862 3.374  -2.234   1.887   28.963   -2.143 1.371  3.374  
3.761   4.453   29.108   11 BB_DG12DT13:DA21DC22_EE B 12 ? E 22 ? B 13 ? E 21 ? 
1 B DT 13 1_555 E DA 5  1_555 B DG 14 1_555 E DC 4  1_555 2.062  2.670  -1.134 174.030  -30.431 120.118  1.305  -1.207 -0.199 
-15.254 -87.234 178.338  12 BB_DT13DG14:DC20DA21_EE B 13 ? E 21 ? B 14 ? E 20 ? 
1 B DG 14 1_555 E DC 4  1_555 B DG 15 1_555 E DC 3  1_555 1.608  2.994  -0.265 -124.448 111.177 -157.089 -1.475 0.830  -0.417 
-55.675 -62.321 -177.399 13 BB_DG14DG15:DC19DC20_EE B 14 ? E 20 ? B 15 ? E 19 ? 
1 B DG 15 1_555 E DC 3  1_555 B DG 16 1_555 E DC 2  1_555 -0.431 0.166  3.296  -2.035   4.511   34.841   -0.408 0.405  3.310  
7.486   3.377   35.180   14 BB_DG15DG16:DC18DC19_EE B 15 ? E 19 ? B 16 ? E 18 ? 
1 D DA 2  1_555 F DT 16 1_555 D DT 3  1_555 F DA 15 1_555 -0.226 -0.854 3.041  1.530    -3.176  24.073   -1.084 0.991  3.105  
-7.564  -3.643  24.326   15 DD_DA2DT3:DA31DT32_FF   D 2  ? F 32 ? D 3  ? F 31 ? 
1 D DT 3  1_555 F DA 15 1_555 D DA 4  1_555 F DT 14 1_555 -0.377 -0.031 3.303  -2.723   -3.438  36.484   0.427  0.221  3.310  
-5.467  4.329   36.738   16 DD_DT3DA4:DT30DA31_FF   D 3  ? F 31 ? D 4  ? F 30 ? 
1 D DA 4  1_555 F DT 14 1_555 D DA 5  1_555 F DT 13 1_555 0.519  -0.907 3.266  1.420    -6.903  38.320   -0.502 -0.602 3.389  
-10.408 -2.141  38.939   17 DD_DA4DA5:DT29DT30_FF   D 4  ? F 30 ? D 5  ? F 29 ? 
1 D DA 5  1_555 F DT 13 1_555 D DA 6  1_555 F DT 12 1_555 0.195  -0.878 3.286  0.462    1.319   35.213   -1.647 -0.253 3.255  
2.180   -0.763  35.240   18 DD_DA5DA6:DT28DT29_FF   D 5  ? F 29 ? D 6  ? F 28 ? 
1 D DA 6  1_555 F DT 12 1_555 D DA 7  1_555 F DT 11 1_555 -0.085 -0.836 3.513  -1.160   2.100   31.485   -1.951 -0.073 3.452  
3.862   2.134   31.574   19 DD_DA6DA7:DT27DT28_FF   D 6  ? F 28 ? D 7  ? F 27 ? 
1 D DA 7  1_555 F DT 11 1_555 D DG 8  1_555 F DC 10 1_555 0.213  -0.197 3.024  -2.659   3.988   25.712   -1.430 -1.133 2.924  
8.863   5.909   26.147   20 DD_DA7DG8:DC26DT27_FF   D 7  ? F 27 ? D 8  ? F 26 ? 
1 D DG 8  1_555 F DC 10 1_555 D DG 9  1_555 F DC 9  1_555 -0.939 0.036  3.417  -2.272   5.530   34.601   -0.814 1.199  3.434  
9.212   3.786   35.098   21 DD_DG8DG9:DC25DC26_FF   D 8  ? F 26 ? D 9  ? F 25 ? 
1 D DG 9  1_555 F DC 9  1_555 D DA 10 1_555 F DT 8  1_555 -0.110 -0.319 3.230  -1.260   6.633   31.277   -1.754 -0.023 3.100  
12.127  2.304   31.980   22 DD_DG9DA10:DT24DC25_FF  D 9  ? F 25 ? D 10 ? F 24 ? 
1 D DA 10 1_555 F DT 8  1_555 D DA 11 1_555 F DT 7  1_555 -0.113 -0.123 3.206  -1.126   2.392   35.032   -0.554 0.023  3.193  
3.966   1.867   35.128   23 DD_DA10DA11:DT23DT24_FF D 10 ? F 24 ? D 11 ? F 23 ? 
1 D DA 11 1_555 F DT 7  1_555 D DG 12 1_555 F DC 6  1_555 -0.253 -0.862 3.718  -0.544   5.250   38.357   -2.022 0.307  3.577  
7.945   0.824   38.705   24 DD_DA11DG12:DC22DT23_FF D 11 ? F 23 ? D 12 ? F 22 ? 
1 D DG 12 1_555 F DC 6  1_555 D DT 13 1_555 F DA 5  1_555 -1.102 -0.835 3.152  -4.060   1.685   26.323   -2.242 1.349  3.224  
3.666   8.836   26.681   25 DD_DG12DT13:DA21DC22_FF D 12 ? F 22 ? D 13 ? F 21 ? 
1 D DT 13 1_555 F DA 5  1_555 D DG 14 1_555 F DC 4  1_555 1.375  -3.453 1.553  -174.816 21.094  134.771  -1.754 -0.916 0.750  
10.565  87.558  178.495  26 DD_DT13DG14:DC20DA21_FF D 13 ? F 21 ? D 14 ? F 20 ? 
1 D DG 14 1_555 F DC 4  1_555 D DG 15 1_555 F DC 3  1_555 1.755  2.381  -0.495 -132.243 116.988 -158.756 -1.159 0.913  -0.535 
-58.514 -66.144 -179.367 27 DD_DG14DG15:DC19DC20_FF D 14 ? F 20 ? D 15 ? F 19 ? 
1 D DG 15 1_555 F DC 3  1_555 D DG 16 1_555 F DC 2  1_555 -0.029 0.053  3.405  0.659    11.153  30.109   -2.003 0.177  3.219  
20.598  -1.218  32.070   28 DD_DG15DG16:DC18DC19_FF D 15 ? F 19 ? D 16 ? F 18 ? 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)'      'United States' HL155178      1 
'National Science Foundation (NSF, United States)'                                         'United States' 'MCB 2028902' 2 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' GM137160      3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8E3K 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 1 2 1' 
_space_group.name_Hall        'C 2y' 
_space_group.IT_number        5 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9CMB 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010995 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.004364 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009734 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.019298 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.pdbx_scat_Cromer_Mann_a5 
_atom_type.pdbx_scat_Cromer_Mann_a6 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.pdbx_scat_Cromer_Mann_b5 
_atom_type.pdbx_scat_Cromer_Mann_b6 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C    ? ? 3.54356  2.42580 ?       ?        ?       ?       25.62398 1.50364  ?       ?       ?       ?        0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H    ? ? 0.51345  0.48472 ?       ?        ?       ?       24.73122 6.32584  ?       ?       ?       ?        0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N    ? ? 4.01032  2.96436 ?       ?        ?       ?       19.97189 1.75589  ?       ?       ?       ?        0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O    ? ? 4.49882  3.47563 ?       ?        ?       ?       15.80542 1.70748  ?       ?       ?       ?        0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O1-  ? ? 5.12366  3.84317 ?       ?        ?       ?       3.49406  27.47979 ?       ?       ?       ?        0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P    ? ? 9.51135  5.44231 ?       ?        ?       ?       1.42069  35.72801 ?       ?       ?       ?        0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S    ? ? 9.55732  6.39887 ?       ?        ?       ?       1.23737  29.19336 ?       ?       ?       ?        0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN   ? ? ?        ?       ?       ?        ?       ?       ?        ?        ?       ?       ?       ?        ?   ? ? 
ZN2+ ? ? 13.65975 6.95497 6.91368 -2.26690 1.63251 1.10620 2.77689  0.25380  7.32919 1.61904 0.01468 19.74356 0.0 
;6-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N      . LYS A 1 5  ? 34.11300  -7.21900  5.64800   1.000 58.59484  ?  169 LYS A N      1 
ATOM   2    C  CA     . LYS A 1 5  ? 35.09000  -6.14400  5.50700   1.000 63.00435  ?  169 LYS A CA     1 
ATOM   3    C  C      . LYS A 1 5  ? 35.02200  -5.13100  6.67300   1.000 61.86315  ?  169 LYS A C      1 
ATOM   4    O  O      . LYS A 1 5  ? 34.57500  -5.45100  7.78700   1.000 62.33073  ?  169 LYS A O      1 
ATOM   5    C  CB     . LYS A 1 5  ? 34.88700  -5.42600  4.17500   1.000 59.86528  ?  169 LYS A CB     1 
ATOM   6    H  HA     . LYS A 1 5  ? 35.98000  -6.53000  5.50300   1.000 75.60522  ?  169 LYS A HA     1 
ATOM   7    N  N      . ILE A 1 6  ? 35.51500  -3.92500  6.41200   1.000 58.94826  ?  170 ILE A N      1 
ATOM   8    C  CA     . ILE A 1 6  ? 35.63500  -2.87000  7.41600   1.000 52.28207  ?  170 ILE A CA     1 
ATOM   9    C  C      . ILE A 1 6  ? 34.50900  -1.86300  7.21500   1.000 54.41375  ?  170 ILE A C      1 
ATOM   10   O  O      . ILE A 1 6  ? 34.21500  -1.44500  6.07700   1.000 51.43782  ?  170 ILE A O      1 
ATOM   11   C  CB     . ILE A 1 6  ? 37.01100  -2.17700  7.33800   1.000 56.03489  ?  170 ILE A CB     1 
ATOM   12   C  CG1    . ILE A 1 6  ? 37.07600  -0.99800  8.31300   1.000 52.00046  ?  170 ILE A CG1    1 
ATOM   13   C  CG2    . ILE A 1 6  ? 37.29700  -1.70200  5.90600   1.000 62.89905  ?  170 ILE A CG2    1 
ATOM   14   C  CD1    . ILE A 1 6  ? 38.36300  -0.24300  8.23300   1.000 51.78515  ?  170 ILE A CD1    1 
ATOM   15   H  H      . ILE A 1 6  ? 35.78900  -3.68600  5.63500   1.000 70.73791  ?  170 ILE A H      1 
ATOM   16   H  HA     . ILE A 1 6  ? 35.54100  -3.25700  8.30100   1.000 62.73849  ?  170 ILE A HA     1 
ATOM   17   H  HB     . ILE A 1 6  ? 37.69200  -2.82000  7.58900   1.000 67.24187  ?  170 ILE A HB     1 
ATOM   18   H  HG12   . ILE A 1 6  ? 36.36500  -0.36900  8.11500   1.000 62.40055  ?  170 ILE A HG12   1 
ATOM   19   H  HG13   . ILE A 1 6  ? 36.98100  -1.33200  9.21900   1.000 62.40055  ?  170 ILE A HG13   1 
ATOM   20   H  HG21   . ILE A 1 6  ? 38.17400  -1.29300  5.87200   1.000 75.47886  ?  170 ILE A HG21   1 
ATOM   21   H  HG22   . ILE A 1 6  ? 37.27800  -2.46100  5.30500   1.000 75.47886  ?  170 ILE A HG22   1 
ATOM   22   H  HG23   . ILE A 1 6  ? 36.62200  -1.05600  5.64500   1.000 75.47886  ?  170 ILE A HG23   1 
ATOM   23   H  HD11   . ILE A 1 6  ? 38.46100  0.29800   9.03200   1.000 62.14218  ?  170 ILE A HD11   1 
ATOM   24   H  HD12   . ILE A 1 6  ? 39.09600  -0.87600  8.17000   1.000 62.14218  ?  170 ILE A HD12   1 
ATOM   25   H  HD13   . ILE A 1 6  ? 38.34900  0.32700   7.44800   1.000 62.14218  ?  170 ILE A HD13   1 
ATOM   26   N  N      . ARG A 1 7  ? 33.88300  -1.46200  8.32400   1.000 50.55067  ?  171 ARG A N      1 
ATOM   27   C  CA     . ARG A 1 7  ? 32.76700  -0.54300  8.26500   1.000 45.69307  ?  171 ARG A CA     1 
ATOM   28   C  C      . ARG A 1 7  ? 33.25500  0.88600   8.07300   1.000 44.96022  ?  171 ARG A C      1 
ATOM   29   O  O      . ARG A 1 7  ? 34.34900  1.26300   8.51900   1.000 38.31462  ?  171 ARG A O      1 
ATOM   30   C  CB     . ARG A 1 7  ? 31.93400  -0.68100  9.52200   1.000 47.63427  ?  171 ARG A CB     1 
ATOM   31   C  CG     . ARG A 1 7  ? 31.52000  -2.11400  9.67200   1.000 51.00933  ?  171 ARG A CG     1 
ATOM   32   C  CD     . ARG A 1 7  ? 30.45700  -2.29300  10.70400  1.000 58.55593  ?  171 ARG A CD     1 
ATOM   33   N  NE     . ARG A 1 7  ? 29.21600  -1.66800  10.26600  1.000 62.29724  ?  171 ARG A NE     1 
ATOM   34   C  CZ     . ARG A 1 7  ? 28.13200  -1.56400  11.01800  1.000 58.82642  ?  171 ARG A CZ     1 
ATOM   35   N  NH1    . ARG A 1 7  ? 28.10200  -2.04100  12.25600  1.000 72.36269  ?  171 ARG A NH1    1 
ATOM   36   N  NH2    . ARG A 1 7  ? 27.05600  -0.95900  10.52500  1.000 57.41424  ?  171 ARG A NH2    1 
ATOM   37   H  H      . ARG A 1 7  ? 34.09200  -1.71200  9.12000   1.000 60.66080  ?  171 ARG A H      1 
ATOM   38   H  HA     . ARG A 1 7  ? 32.20700  -0.77300  7.50700   1.000 54.83168  ?  171 ARG A HA     1 
ATOM   39   H  HB2    . ARG A 1 7  ? 32.46100  -0.42600  10.29500  1.000 57.16112  ?  171 ARG A HB2    1 
ATOM   40   H  HB3    . ARG A 1 7  ? 31.13900  -0.13000  9.45000   1.000 57.16112  ?  171 ARG A HB3    1 
ATOM   41   H  HG2    . ARG A 1 7  ? 31.17500  -2.43500  8.82400   1.000 61.21120  ?  171 ARG A HG2    1 
ATOM   42   H  HG3    . ARG A 1 7  ? 32.28800  -2.64200  9.94100   1.000 61.21120  ?  171 ARG A HG3    1 
ATOM   43   H  HD2    . ARG A 1 7  ? 30.29400  -3.23900  10.84000  1.000 70.26712  ?  171 ARG A HD2    1 
ATOM   44   H  HD3    . ARG A 1 7  ? 30.73700  -1.87400  11.53300  1.000 70.26712  ?  171 ARG A HD3    1 
ATOM   45   H  HE     . ARG A 1 7  ? 29.18600  -1.34700  9.46900   1.000 74.75669  ?  171 ARG A HE     1 
ATOM   46   H  HH11   . ARG A 1 7  ? 28.79300  -2.43200  12.58600  1.000 86.83523  ?  171 ARG A HH11   1 
ATOM   47   H  HH12   . ARG A 1 7  ? 27.38800  -1.96200  12.72900  1.000 86.83523  ?  171 ARG A HH12   1 
ATOM   48   H  HH21   . ARG A 1 7  ? 27.06800  -0.64600  9.72400   1.000 68.89709  ?  171 ARG A HH21   1 
ATOM   49   H  HH22   . ARG A 1 7  ? 26.34600  -0.88500  11.00500  1.000 68.89709  ?  171 ARG A HH22   1 
ATOM   50   N  N      . LEU A 1 8  ? 32.41700  1.68000   7.39000   1.000 40.81757  ?  172 LEU A N      1 
ATOM   51   C  CA     . LEU A 1 8  ? 32.75700  3.06300   7.08000   1.000 39.01949  ?  172 LEU A CA     1 
ATOM   52   C  C      . LEU A 1 8  ? 33.05800  3.87700   8.34500   1.000 38.93970  ?  172 LEU A C      1 
ATOM   53   O  O      . LEU A 1 8  ? 34.03300  4.63000   8.39400   1.000 37.21237  ?  172 LEU A O      1 
ATOM   54   C  CB     . LEU A 1 8  ? 31.61000  3.70400   6.29100   1.000 38.35070  ?  172 LEU A CB     1 
ATOM   55   C  CG     . LEU A 1 8  ? 31.63000  5.21100   6.03800   1.000 40.34657  ?  172 LEU A CG     1 
ATOM   56   C  CD1    . LEU A 1 8  ? 32.90700  5.64300   5.29400   1.000 30.72293  ?  172 LEU A CD1    1 
ATOM   57   C  CD2    . LEU A 1 8  ? 30.40400  5.62700   5.19300   1.000 40.02824  ?  172 LEU A CD2    1 
ATOM   58   H  H      . LEU A 1 8  ? 31.64600  1.43500   7.09800   1.000 48.98109  ?  172 LEU A H      1 
ATOM   59   H  HA     . LEU A 1 8  ? 33.54900  3.07500   6.52100   1.000 46.82338  ?  172 LEU A HA     1 
ATOM   60   H  HB2    . LEU A 1 8  ? 31.57700  3.27700   5.42100   1.000 46.02084  ?  172 LEU A HB2    1 
ATOM   61   H  HB3    . LEU A 1 8  ? 30.78500  3.51300   6.76400   1.000 46.02084  ?  172 LEU A HB3    1 
ATOM   62   H  HG     . LEU A 1 8  ? 31.59200  5.68300   6.88400   1.000 48.41589  ?  172 LEU A HG     1 
ATOM   63   H  HD11   . LEU A 1 8  ? 32.92400  6.61100   5.27400   1.000 36.86751  ?  172 LEU A HD11   1 
ATOM   64   H  HD12   . LEU A 1 8  ? 33.68300  5.30600   5.76800   1.000 36.86751  ?  172 LEU A HD12   1 
ATOM   65   H  HD13   . LEU A 1 8  ? 32.88500  5.28500   4.39300   1.000 36.86751  ?  172 LEU A HD13   1 
ATOM   66   H  HD21   . LEU A 1 8  ? 30.45900  6.57700   5.00400   1.000 48.03389  ?  172 LEU A HD21   1 
ATOM   67   H  HD22   . LEU A 1 8  ? 30.40700  5.12400   4.36400   1.000 48.03389  ?  172 LEU A HD22   1 
ATOM   68   H  HD23   . LEU A 1 8  ? 29.59600  5.43500   5.69400   1.000 48.03389  ?  172 LEU A HD23   1 
ATOM   69   N  N      . TYR A 1 9  ? 32.20700  3.78500   9.37100   1.000 40.20456  ?  173 TYR A N      1 
ATOM   70   C  CA     . TYR A 1 9  ? 32.51000  4.57800   10.57100  1.000 42.63392  ?  173 TYR A CA     1 
ATOM   71   C  C      . TYR A 1 9  ? 33.87100  4.19600   11.16000  1.000 37.67439  ?  173 TYR A C      1 
ATOM   72   O  O      . TYR A 1 9  ? 34.62800  5.06500   11.59400  1.000 36.43232  ?  173 TYR A O      1 
ATOM   73   C  CB     . TYR A 1 9  ? 31.40400  4.43900   11.62300  1.000 41.84685  ?  173 TYR A CB     1 
ATOM   74   C  CG     . TYR A 1 9  ? 31.34700  3.14800   12.34500  1.000 41.44008  ?  173 TYR A CG     1 
ATOM   75   C  CD1    . TYR A 1 9  ? 32.17200  2.90600   13.41900  1.000 46.95348  ?  173 TYR A CD1    1 
ATOM   76   C  CD2    . TYR A 1 9  ? 30.44100  2.18000   11.98900  1.000 45.98067  ?  173 TYR A CD2    1 
ATOM   77   C  CE1    . TYR A 1 9  ? 32.11600  1.74100   14.10100  1.000 48.87886  ?  173 TYR A CE1    1 
ATOM   78   C  CE2    . TYR A 1 9  ? 30.38200  0.97700   12.67900  1.000 50.79078  ?  173 TYR A CE2    1 
ATOM   79   C  CZ     . TYR A 1 9  ? 31.22900  0.77500   13.74400  1.000 50.08844  ?  173 TYR A CZ     1 
ATOM   80   O  OH     . TYR A 1 9  ? 31.20600  -0.39100  14.49000  1.000 56.38450  ?  173 TYR A OH     1 
ATOM   81   H  H      . TYR A 1 9  ? 31.49400  3.30600   9.40300   1.000 48.24547  ?  173 TYR A H      1 
ATOM   82   H  HA     . TYR A 1 9  ? 32.55500  5.51300   10.31800  1.000 51.16070  ?  173 TYR A HA     1 
ATOM   83   H  HB2    . TYR A 1 9  ? 31.52600  5.13500   12.28700  1.000 50.21622  ?  173 TYR A HB2    1 
ATOM   84   H  HB3    . TYR A 1 9  ? 30.54800  4.56100   11.18300  1.000 50.21622  ?  173 TYR A HB3    1 
ATOM   85   H  HD1    . TYR A 1 9  ? 32.78400  3.55600   13.67800  1.000 56.34418  ?  173 TYR A HD1    1 
ATOM   86   H  HD2    . TYR A 1 9  ? 29.87200  2.32500   11.26800  1.000 55.17681  ?  173 TYR A HD2    1 
ATOM   87   H  HE1    . TYR A 1 9  ? 32.68600  1.60000   14.82200  1.000 58.65463  ?  173 TYR A HE1    1 
ATOM   88   H  HE2    . TYR A 1 9  ? 29.76800  0.32300   12.43400  1.000 60.94894  ?  173 TYR A HE2    1 
ATOM   89   H  HH     . TYR A 1 9  ? 30.62500  -0.91600  14.18500  1.000 67.66140  ?  173 TYR A HH     1 
ATOM   90   N  N      . GLN A 1 10 ? 34.20100  2.90400   11.14300  1.000 39.60370  ?  174 GLN A N      1 
ATOM   91   C  CA     . GLN A 1 10 ? 35.48700  2.41600   11.63200  1.000 42.59770  ?  174 GLN A CA     1 
ATOM   92   C  C      . GLN A 1 10 ? 36.66200  2.96500   10.82300  1.000 44.63613  ?  174 GLN A C      1 
ATOM   93   O  O      . GLN A 1 10 ? 37.69100  3.36500   11.37800  1.000 42.61023  ?  174 GLN A O      1 
ATOM   94   C  CB     . GLN A 1 10 ? 35.48500  0.89000   11.58800  1.000 41.94971  ?  174 GLN A CB     1 
ATOM   95   C  CG     . GLN A 1 10 ? 36.61500  0.28400   12.34300  1.000 58.42312  ?  174 GLN A CG     1 
ATOM   96   C  CD     . GLN A 1 10 ? 36.49300  0.56600   13.83700  1.000 63.80255  ?  174 GLN A CD     1 
ATOM   97   O  OE1    . GLN A 1 10 ? 35.67400  -0.05500  14.52700  1.000 60.39853  ?  174 GLN A OE1    1 
ATOM   98   N  NE2    . GLN A 1 10 ? 37.27800  1.53400   14.33200  1.000 56.87252  ?  174 GLN A NE2    1 
ATOM   99   H  H      . GLN A 1 10 ? 33.68600  2.28100   10.84700  1.000 47.52444  ?  174 GLN A H      1 
ATOM   100  H  HA     . GLN A 1 10 ? 35.59900  2.69800   12.55300  1.000 51.11724  ?  174 GLN A HA     1 
ATOM   101  H  HB2    . GLN A 1 10 ? 34.65800  0.56500   11.97600  1.000 50.33965  ?  174 GLN A HB2    1 
ATOM   102  H  HB3    . GLN A 1 10 ? 35.55400  0.60100   10.66500  1.000 50.33965  ?  174 GLN A HB3    1 
ATOM   103  H  HG2    . GLN A 1 10 ? 36.60700  -0.67700  12.21400  1.000 70.10775  ?  174 GLN A HG2    1 
ATOM   104  H  HG3    . GLN A 1 10 ? 37.45300  0.65800   12.02900  1.000 70.10775  ?  174 GLN A HG3    1 
ATOM   105  H  HE21   . GLN A 1 10 ? 37.82900  1.94600   13.81600  1.000 68.24702  ?  174 GLN A HE21   1 
ATOM   106  H  HE22   . GLN A 1 10 ? 37.24200  1.73100   15.16800  1.000 68.24702  ?  174 GLN A HE22   1 
ATOM   107  N  N      . PHE A 1 11 ? 36.54000  2.91900   9.50000   1.000 42.29484  ?  175 PHE A N      1 
ATOM   108  C  CA     . PHE A 1 11 ? 37.51400  3.52900   8.59700   1.000 37.98561  ?  175 PHE A CA     1 
ATOM   109  C  C      . PHE A 1 11 ? 37.74100  4.99600   8.95300   1.000 38.32628  ?  175 PHE A C      1 
ATOM   110  O  O      . PHE A 1 11 ? 38.88300  5.46600   9.10800   1.000 41.81970  ?  175 PHE A O      1 
ATOM   111  C  CB     . PHE A 1 11 ? 36.98600  3.34600   7.15700   1.000 40.48071  ?  175 PHE A CB     1 
ATOM   112  C  CG     . PHE A 1 11 ? 37.70700  4.13500   6.14400   1.000 41.63004  ?  175 PHE A CG     1 
ATOM   113  C  CD1    . PHE A 1 11 ? 38.89900  3.67400   5.62500   1.000 43.45898  ?  175 PHE A CD1    1 
ATOM   114  C  CD2    . PHE A 1 11 ? 37.21400  5.33000   5.69900   1.000 39.36379  ?  175 PHE A CD2    1 
ATOM   115  C  CE1    . PHE A 1 11 ? 39.59200  4.37400   4.68100   1.000 42.83432  ?  175 PHE A CE1    1 
ATOM   116  C  CE2    . PHE A 1 11 ? 37.92400  6.05400   4.71800   1.000 42.10393  ?  175 PHE A CE2    1 
ATOM   117  C  CZ     . PHE A 1 11 ? 39.11500  5.56400   4.22100   1.000 42.61786  ?  175 PHE A CZ     1 
ATOM   118  H  H      . PHE A 1 11 ? 35.88900  2.53300   9.09200   1.000 50.75381  ?  175 PHE A H      1 
ATOM   119  H  HA     . PHE A 1 11 ? 38.36100  3.06200   8.67400   1.000 45.58273  ?  175 PHE A HA     1 
ATOM   120  H  HB2    . PHE A 1 11 ? 37.06500  2.41000   6.91300   1.000 48.57686  ?  175 PHE A HB2    1 
ATOM   121  H  HB3    . PHE A 1 11 ? 36.05400  3.61400   7.13100   1.000 48.57686  ?  175 PHE A HB3    1 
ATOM   122  H  HD1    . PHE A 1 11 ? 39.23800  2.86200   5.92500   1.000 52.15077  ?  175 PHE A HD1    1 
ATOM   123  H  HD2    . PHE A 1 11 ? 36.41000  5.65800   6.03200   1.000 47.23654  ?  175 PHE A HD2    1 
ATOM   124  H  HE1    . PHE A 1 11 ? 40.39300  4.03700   4.35000   1.000 51.40119  ?  175 PHE A HE1    1 
ATOM   125  H  HE2    . PHE A 1 11 ? 37.59400  6.86800   4.41200   1.000 50.52472  ?  175 PHE A HE2    1 
ATOM   126  H  HZ     . PHE A 1 11 ? 39.58800  6.04300   3.57900   1.000 51.14143  ?  175 PHE A HZ     1 
ATOM   127  N  N      . LEU A 1 12 ? 36.64600  5.73800   9.10800   1.000 36.07660  ?  176 LEU A N      1 
ATOM   128  C  CA     . LEU A 1 12 ? 36.77200  7.14700   9.44600   1.000 38.93239  ?  176 LEU A CA     1 
ATOM   129  C  C      . LEU A 1 12 ? 37.42300  7.33500   10.82700  1.000 40.67706  ?  176 LEU A C      1 
ATOM   130  O  O      . LEU A 1 12 ? 38.26500  8.22400   11.02300  1.000 40.14517  ?  176 LEU A O      1 
ATOM   131  C  CB     . LEU A 1 12 ? 35.38900  7.79000   9.42400   1.000 35.42110  ?  176 LEU A CB     1 
ATOM   132  C  CG     . LEU A 1 12 ? 34.67300  7.89600   8.07600   1.000 37.50399  ?  176 LEU A CG     1 
ATOM   133  C  CD1    . LEU A 1 12 ? 33.33000  8.62900   8.30700   1.000 36.39128  ?  176 LEU A CD1    1 
ATOM   134  C  CD2    . LEU A 1 12 ? 35.58300  8.57200   6.99900   1.000 35.74845  ?  176 LEU A CD2    1 
ATOM   135  H  H      . LEU A 1 12 ? 35.83800  5.45500   9.02500   1.000 43.29192  ?  176 LEU A H      1 
ATOM   136  H  HA     . LEU A 1 12 ? 37.33000  7.58800   8.78700   1.000 46.71887  ?  176 LEU A HA     1 
ATOM   137  H  HB2    . LEU A 1 12 ? 34.81200  7.27700   10.01100  1.000 42.50532  ?  176 LEU A HB2    1 
ATOM   138  H  HB3    . LEU A 1 12 ? 35.47300  8.69200   9.77100   1.000 42.50532  ?  176 LEU A HB3    1 
ATOM   139  H  HG     . LEU A 1 12 ? 34.46800  7.00100   7.76400   1.000 45.00479  ?  176 LEU A HG     1 
ATOM   140  H  HD11   . LEU A 1 12 ? 32.86200  8.70400   7.46100   1.000 43.66954  ?  176 LEU A HD11   1 
ATOM   141  H  HD12   . LEU A 1 12 ? 32.79700  8.11900   8.93700   1.000 43.66954  ?  176 LEU A HD12   1 
ATOM   142  H  HD13   . LEU A 1 12 ? 33.51000  9.51200   8.66500   1.000 43.66954  ?  176 LEU A HD13   1 
ATOM   143  H  HD21   . LEU A 1 12 ? 35.05500  8.74500   6.20400   1.000 42.89814  ?  176 LEU A HD21   1 
ATOM   144  H  HD22   . LEU A 1 12 ? 35.92700  9.40600   7.35600   1.000 42.89814  ?  176 LEU A HD22   1 
ATOM   145  H  HD23   . LEU A 1 12 ? 36.31700  7.97600   6.78600   1.000 42.89814  ?  176 LEU A HD23   1 
ATOM   146  N  N      . LEU A 1 13 ? 37.01000  6.53800   11.80300  1.000 42.91463  ?  177 LEU A N      1 
ATOM   147  C  CA     . LEU A 1 13 ? 37.54000  6.72900   13.14800  1.000 41.12440  ?  177 LEU A CA     1 
ATOM   148  C  C      . LEU A 1 13 ? 39.03100  6.42400   13.17500  1.000 45.69587  ?  177 LEU A C      1 
ATOM   149  O  O      . LEU A 1 13 ? 39.78700  7.11400   13.87600  1.000 46.22798  ?  177 LEU A O      1 
ATOM   150  C  CB     . LEU A 1 13 ? 36.78600  5.85600   14.15600  1.000 43.32162  ?  177 LEU A CB     1 
ATOM   151  C  CG     . LEU A 1 13 ? 37.18800  5.99300   15.64700  1.000 48.61532  ?  177 LEU A CG     1 
ATOM   152  C  CD1    . LEU A 1 13 ? 36.90600  7.37800   16.26100  1.000 44.55357  ?  177 LEU A CD1    1 
ATOM   153  C  CD2    . LEU A 1 13 ? 36.48400  4.89700   16.48900  1.000 52.16027  ?  177 LEU A CD2    1 
ATOM   154  H  H      . LEU A 1 13 ? 36.44200  5.89800   11.72000  1.000 51.49756  ?  177 LEU A H      1 
ATOM   155  H  HA     . LEU A 1 13 ? 37.41900  7.65600   13.40600  1.000 49.34928  ?  177 LEU A HA     1 
ATOM   156  H  HB2    . LEU A 1 13 ? 35.84200  6.07100   14.09400  1.000 51.98594  ?  177 LEU A HB2    1 
ATOM   157  H  HB3    . LEU A 1 13 ? 36.91900  4.92700   13.90900  1.000 51.98594  ?  177 LEU A HB3    1 
ATOM   158  H  HG     . LEU A 1 13 ? 38.14300  5.83800   15.71900  1.000 58.33838  ?  177 LEU A HG     1 
ATOM   159  H  HD11   . LEU A 1 13 ? 37.19200  7.37600   17.18800  1.000 53.46429  ?  177 LEU A HD11   1 
ATOM   160  H  HD12   . LEU A 1 13 ? 37.39900  8.04900   15.76400  1.000 53.46429  ?  177 LEU A HD12   1 
ATOM   161  H  HD13   . LEU A 1 13 ? 35.95400  7.55900   16.20800  1.000 53.46429  ?  177 LEU A HD13   1 
ATOM   162  H  HD21   . LEU A 1 13 ? 36.58900  5.10400   17.43000  1.000 62.59232  ?  177 LEU A HD21   1 
ATOM   163  H  HD22   . LEU A 1 13 ? 35.54200  4.88000   16.25800  1.000 62.59232  ?  177 LEU A HD22   1 
ATOM   164  H  HD23   . LEU A 1 13 ? 36.88800  4.03800   16.28900  1.000 62.59232  ?  177 LEU A HD23   1 
ATOM   165  N  N      . ASP A 1 14 ? 39.46100  5.38500   12.42500  1.000 46.14394  ?  178 ASP A N      1 
ATOM   166  C  CA     . ASP A 1 14 ? 40.87200  4.98800   12.38400  1.000 47.04021  ?  178 ASP A CA     1 
ATOM   167  C  C      . ASP A 1 14 ? 41.73500  6.08100   11.76300  1.000 51.46960  ?  178 ASP A C      1 
ATOM   168  O  O      . ASP A 1 14 ? 42.86800  6.33900   12.22100  1.000 50.31967  ?  178 ASP A O      1 
ATOM   169  C  CB     . ASP A 1 14 ? 41.06200  3.70200   11.57300  1.000 44.58650  ?  178 ASP A CB     1 
ATOM   170  C  CG     . ASP A 1 14 ? 40.69400  2.44400   12.34700  1.000 56.21295  ?  178 ASP A CG     1 
ATOM   171  O  OD1    . ASP A 1 14 ? 40.45000  2.55000   13.57300  1.000 62.88050  ?  178 ASP A OD1    1 
ATOM   172  O  OD2    . ASP A 1 14 ? 40.64900  1.34500   11.72200  1.000 65.41987  -1 178 ASP A OD2    1 
ATOM   173  H  H      . ASP A 1 14 ? 38.94900  4.89900   11.93400  1.000 55.37273  ?  178 ASP A H      1 
ATOM   174  H  HA     . ASP A 1 14 ? 41.18700  4.83100   13.28800  1.000 56.44825  ?  178 ASP A HA     1 
ATOM   175  H  HB2    . ASP A 1 14 ? 40.49900  3.74200   10.78400  1.000 53.50381  ?  178 ASP A HB2    1 
ATOM   176  H  HB3    . ASP A 1 14 ? 41.99300  3.63000   11.31200  1.000 53.50381  ?  178 ASP A HB3    1 
ATOM   177  N  N      . LEU A 1 15 ? 41.22400  6.73400   10.72100  1.000 41.36821  ?  179 LEU A N      1 
ATOM   178  C  CA     . LEU A 1 15 ? 41.99100  7.84800   10.16900  1.000 46.04722  ?  179 LEU A CA     1 
ATOM   179  C  C      . LEU A 1 15 ? 42.09800  8.97500   11.19400  1.000 51.93444  ?  179 LEU A C      1 
ATOM   180  O  O      . LEU A 1 15 ? 43.14400  9.64200   11.28900  1.000 50.34813  ?  179 LEU A O      1 
ATOM   181  C  CB     . LEU A 1 15 ? 41.36500  8.38100   8.88200   1.000 42.77657  ?  179 LEU A CB     1 
ATOM   182  C  CG     . LEU A 1 15 ? 41.37000  7.52800   7.60800   1.000 47.43111  ?  179 LEU A CG     1 
ATOM   183  C  CD1    . LEU A 1 15 ? 40.23200  8.01600   6.69500   1.000 49.28367  ?  179 LEU A CD1    1 
ATOM   184  C  CD2    . LEU A 1 15 ? 42.69900  7.59500   6.84700   1.000 45.84300  ?  179 LEU A CD2    1 
ATOM   185  H  H      . LEU A 1 15 ? 40.47600  6.56400   10.33300  1.000 49.64185  ?  179 LEU A H      1 
ATOM   186  H  HA     . LEU A 1 15 ? 42.88700  7.54100   9.96300   1.000 55.25666  ?  179 LEU A HA     1 
ATOM   187  H  HB2    . LEU A 1 15 ? 40.43500  8.58000   9.07400   1.000 51.33188  ?  179 LEU A HB2    1 
ATOM   188  H  HB3    . LEU A 1 15 ? 41.81900  9.20900   8.66000   1.000 51.33188  ?  179 LEU A HB3    1 
ATOM   189  H  HG     . LEU A 1 15 ? 41.19800  6.60200   7.84100   1.000 56.91734  ?  179 LEU A HG     1 
ATOM   190  H  HD11   . LEU A 1 15 ? 40.27200  7.53200   5.85600   1.000 59.14040  ?  179 LEU A HD11   1 
ATOM   191  H  HD12   . LEU A 1 15 ? 39.38200  7.85000   7.13300   1.000 59.14040  ?  179 LEU A HD12   1 
ATOM   192  H  HD13   . LEU A 1 15 ? 40.34200  8.96600   6.53400   1.000 59.14040  ?  179 LEU A HD13   1 
ATOM   193  H  HD21   . LEU A 1 15 ? 42.57000  7.24700   5.95100   1.000 55.01160  ?  179 LEU A HD21   1 
ATOM   194  H  HD22   . LEU A 1 15 ? 42.98900  8.51900   6.80700   1.000 55.01160  ?  179 LEU A HD22   1 
ATOM   195  H  HD23   . LEU A 1 15 ? 43.35900  7.06300   7.31900   1.000 55.01160  ?  179 LEU A HD23   1 
ATOM   196  N  N      . LEU A 1 16 ? 41.01200  9.21800   11.95400  1.000 41.70818  ?  180 LEU A N      1 
ATOM   197  C  CA     . LEU A 1 16 ? 41.04300  10.32800  12.90600  1.000 42.85250  ?  180 LEU A CA     1 
ATOM   198  C  C      . LEU A 1 16 ? 42.02100  10.04200  14.06900  1.000 47.68869  ?  180 LEU A C      1 
ATOM   199  O  O      . LEU A 1 16 ? 42.85500  10.88300  14.41700  1.000 44.22655  ?  180 LEU A O      1 
ATOM   200  C  CB     . LEU A 1 16 ? 39.63600  10.61100  13.41700  1.000 44.38764  ?  180 LEU A CB     1 
ATOM   201  C  CG     . LEU A 1 16 ? 38.77000  11.38200  12.39900  1.000 41.36733  ?  180 LEU A CG     1 
ATOM   202  C  CD1    . LEU A 1 16 ? 37.31400  11.03200  12.54900  1.000 36.73631  ?  180 LEU A CD1    1 
ATOM   203  C  CD2    . LEU A 1 16 ? 38.97100  12.86600  12.58400  1.000 43.78137  ?  180 LEU A CD2    1 
ATOM   204  H  H      . LEU A 1 16 ? 40.27800  8.77100   11.93500  1.000 50.04981  ?  180 LEU A H      1 
ATOM   205  H  HA     . LEU A 1 16 ? 41.35600  11.12300  12.44700  1.000 51.42300  ?  180 LEU A HA     1 
ATOM   206  H  HB2    . LEU A 1 16 ? 39.19500  9.76900   13.60800  1.000 53.26517  ?  180 LEU A HB2    1 
ATOM   207  H  HB3    . LEU A 1 16 ? 39.69500  11.14500  14.22500  1.000 53.26517  ?  180 LEU A HB3    1 
ATOM   208  H  HG     . LEU A 1 16 ? 39.04800  11.14700  11.50000  1.000 49.64079  ?  180 LEU A HG     1 
ATOM   209  H  HD11   . LEU A 1 16 ? 36.80000  11.53800  11.90100  1.000 44.08357  ?  180 LEU A HD11   1 
ATOM   210  H  HD12   . LEU A 1 16 ? 37.20000  10.08100  12.39300  1.000 44.08357  ?  180 LEU A HD12   1 
ATOM   211  H  HD13   . LEU A 1 16 ? 37.02700  11.25700  13.44800  1.000 44.08357  ?  180 LEU A HD13   1 
ATOM   212  H  HD21   . LEU A 1 16 ? 38.44100  13.34000  11.92500  1.000 52.53764  ?  180 LEU A HD21   1 
ATOM   213  H  HD22   . LEU A 1 16 ? 38.68700  13.11400  13.47800  1.000 52.53764  ?  180 LEU A HD22   1 
ATOM   214  H  HD23   . LEU A 1 16 ? 39.91100  13.07400  12.46500  1.000 52.53764  ?  180 LEU A HD23   1 
ATOM   215  N  N      . ARG A 1 17 ? 41.96200  8.83100   14.62100  1.000 45.33511  ?  181 ARG A N      1 
ATOM   216  C  CA     . ARG A 1 17 ? 42.79100  8.42600   15.73900  1.000 49.45448  ?  181 ARG A CA     1 
ATOM   217  C  C      . ARG A 1 17 ? 44.25200  8.22200   15.37000  1.000 50.81431  ?  181 ARG A C      1 
ATOM   218  O  O      . ARG A 1 17 ? 45.10800  8.27800   16.26200  1.000 43.73106  ?  181 ARG A O      1 
ATOM   219  C  CB     . ARG A 1 17 ? 42.22100  7.14100   16.33400  1.000 49.05792  ?  181 ARG A CB     1 
ATOM   220  C  CG     . ARG A 1 17 ? 41.03900  7.40300   17.16500  1.000 47.81494  ?  181 ARG A CG     1 
ATOM   221  C  CD     . ARG A 1 17 ? 40.53300  6.12800   17.79100  1.000 54.08311  ?  181 ARG A CD     1 
ATOM   222  N  NE     . ARG A 1 17 ? 39.48600  6.38300   18.76000  1.000 51.76043  ?  181 ARG A NE     1 
ATOM   223  C  CZ     . ARG A 1 17 ? 38.62700  5.46000   19.17500  1.000 61.94887  ?  181 ARG A CZ     1 
ATOM   224  N  NH1    . ARG A 1 17 ? 38.69800  4.20900   18.73900  1.000 61.90546  ?  181 ARG A NH1    1 
ATOM   225  N  NH2    . ARG A 1 17 ? 37.66300  5.80300   20.03100  1.000 62.36147  ?  181 ARG A NH2    1 
ATOM   226  H  H      . ARG A 1 17 ? 41.43000  8.21200   14.35100  1.000 54.40213  ?  181 ARG A H      1 
ATOM   227  H  HA     . ARG A 1 17 ? 42.75200  9.11300   16.42200  1.000 59.34538  ?  181 ARG A HA     1 
ATOM   228  H  HB2    . ARG A 1 17 ? 41.96000  6.54400   15.61500  1.000 58.86951  ?  181 ARG A HB2    1 
ATOM   229  H  HB3    . ARG A 1 17 ? 42.89500  6.72100   16.89000  1.000 58.86951  ?  181 ARG A HB3    1 
ATOM   230  H  HG2    . ARG A 1 17 ? 41.27400  8.02000   17.87500  1.000 57.37793  ?  181 ARG A HG2    1 
ATOM   231  H  HG3    . ARG A 1 17 ? 40.33300  7.77500   16.61300  1.000 57.37793  ?  181 ARG A HG3    1 
ATOM   232  H  HD2    . ARG A 1 17 ? 40.17100  5.55500   17.09700  1.000 64.89973  ?  181 ARG A HD2    1 
ATOM   233  H  HD3    . ARG A 1 17 ? 41.26500  5.68300   18.24600  1.000 64.89973  ?  181 ARG A HD3    1 
ATOM   234  H  HE     . ARG A 1 17 ? 39.48900  7.14100   19.16600  1.000 62.11251  ?  181 ARG A HE     1 
ATOM   235  H  HH11   . ARG A 1 17 ? 39.31200  3.97700   18.18400  1.000 74.28656  ?  181 ARG A HH11   1 
ATOM   236  H  HH12   . ARG A 1 17 ? 38.13100  3.62600   19.01800  1.000 74.28656  ?  181 ARG A HH12   1 
ATOM   237  H  HH21   . ARG A 1 17 ? 37.61000  6.61200   20.31700  1.000 74.83376  ?  181 ARG A HH21   1 
ATOM   238  H  HH22   . ARG A 1 17 ? 37.10300  5.21200   20.30600  1.000 74.83376  ?  181 ARG A HH22   1 
ATOM   239  N  N      . SER A 1 18 ? 44.56700  8.00500   14.08800  1.000 50.83587  ?  182 SER A N      1 
ATOM   240  C  CA     . SER A 1 18 ? 45.96600  7.95100   13.69300  1.000 47.37873  ?  182 SER A CA     1 
ATOM   241  C  C      . SER A 1 18 ? 46.46500  9.20000   12.98300  1.000 50.25736  ?  182 SER A C      1 
ATOM   242  O  O      . SER A 1 18 ? 47.67900  9.37100   12.86500  1.000 55.73840  ?  182 SER A O      1 
ATOM   243  C  CB     . SER A 1 18 ? 46.23000  6.73300   12.79600  1.000 49.18569  ?  182 SER A CB     1 
ATOM   244  O  OG     . SER A 1 18 ? 45.45100  6.77500   11.64200  1.000 45.96926  ?  182 SER A OG     1 
ATOM   245  H  H      . SER A 1 18 ? 44.00300  7.89000   13.44900  1.000 61.00304  ?  182 SER A H      1 
ATOM   246  H  HA     . SER A 1 18 ? 46.51000  7.83900   14.48700  1.000 56.85447  ?  182 SER A HA     1 
ATOM   247  H  HB2    . SER A 1 18 ? 47.16600  6.72600   12.54300  1.000 59.02283  ?  182 SER A HB2    1 
ATOM   248  H  HB3    . SER A 1 18 ? 46.01600  5.92600   13.29000  1.000 59.02283  ?  182 SER A HB3    1 
ATOM   249  H  HG     . SER A 1 18 ? 44.63600  6.77800   11.84500  1.000 55.16312  ?  182 SER A HG     1 
ATOM   250  N  N      . GLY A 1 19 ? 45.60000  10.15800  12.68100  1.000 54.12338  ?  183 GLY A N      1 
ATOM   251  C  CA     . GLY A 1 19 ? 46.02800  11.46700  12.15400  1.000 50.99284  ?  183 GLY A CA     1 
ATOM   252  C  C      . GLY A 1 19 ? 46.40400  11.49800  10.69000  1.000 54.68441  ?  183 GLY A C      1 
ATOM   253  O  O      . GLY A 1 19 ? 47.03200  12.49000  10.30700  1.000 54.99690  ?  183 GLY A O      1 
ATOM   254  H  H      . GLY A 1 19 ? 44.74800  10.08300  12.77000  1.000 64.94806  ?  183 GLY A H      1 
ATOM   255  H  HA2    . GLY A 1 19 ? 45.31100  12.10600  12.28800  1.000 61.19140  ?  183 GLY A HA2    1 
ATOM   256  H  HA3    . GLY A 1 19 ? 46.79600  11.77100  12.66300  1.000 61.19140  ?  183 GLY A HA3    1 
ATOM   257  N  N      . ASP A 1 20 ? 46.05200  10.49000  9.89400   1.000 53.59878  ?  184 ASP A N      1 
ATOM   258  C  CA     . ASP A 1 20 ? 46.27700  10.55600  8.42400   1.000 58.48662  ?  184 ASP A CA     1 
ATOM   259  C  C      . ASP A 1 20 ? 45.10900  11.32900  7.82100   1.000 55.25386  ?  184 ASP A C      1 
ATOM   260  O  O      . ASP A 1 20 ? 44.04100  11.35500  8.44600   1.000 53.30027  ?  184 ASP A O      1 
ATOM   261  C  CB     . ASP A 1 20 ? 46.48400  9.22900   7.67900   1.000 54.74373  ?  184 ASP A CB     1 
ATOM   262  C  CG     . ASP A 1 20 ? 45.85700  7.97800   8.25400   1.000 66.15052  ?  184 ASP A CG     1 
ATOM   263  O  OD1    . ASP A 1 20 ? 45.09700  8.09500   9.21000   1.000 69.49787  ?  184 ASP A OD1    1 
ATOM   264  O  OD2    . ASP A 1 20 ? 46.13100  6.89500   7.71000   1.000 72.28058  -1 184 ASP A OD2    1 
ATOM   265  H  H      . ASP A 1 20 ? 45.68500  9.76100   10.16400  1.000 64.31854  ?  184 ASP A H      1 
ATOM   266  H  HA     . ASP A 1 20 ? 47.07500  11.08600  8.27100   1.000 70.18394  ?  184 ASP A HA     1 
ATOM   267  H  HB2    . ASP A 1 20 ? 46.13000  9.33400   6.78200   1.000 65.69248  ?  184 ASP A HB2    1 
ATOM   268  H  HB3    . ASP A 1 20 ? 47.43800  9.06500   7.62400   1.000 65.69248  ?  184 ASP A HB3    1 
ATOM   269  N  N      . MET A 1 21 ? 45.33900  11.98200  6.68900   1.000 50.15617  ?  185 MET A N      1 
ATOM   270  C  CA     . MET A 1 21 ? 44.30700  12.74600  5.95700   1.000 50.58542  ?  185 MET A CA     1 
ATOM   271  C  C      . MET A 1 21 ? 43.77900  13.84600  6.86700   1.000 53.10217  ?  185 MET A C      1 
ATOM   272  O  O      . MET A 1 21 ? 42.61000  13.92400  7.00000   1.000 53.27210  ?  185 MET A O      1 
ATOM   273  C  CB     . MET A 1 21 ? 43.19600  11.80700  5.49000   1.000 47.48556  ?  185 MET A CB     1 
ATOM   274  C  CG     . MET A 1 21 ? 43.75700  10.59500  4.77100   1.000 59.88205  ?  185 MET A CG     1 
ATOM   275  S  SD     . MET A 1 21 ? 42.68400  9.91000   3.50200   1.000 53.99020  ?  185 MET A SD     1 
ATOM   276  C  CE     . MET A 1 21 ? 42.53700  11.30800  2.39400   1.000 54.17109  ?  185 MET A CE     1 
ATOM   277  H  H      . MET A 1 21 ? 46.10800  12.00400  6.30500   1.000 60.18741  ?  185 MET A H      1 
ATOM   278  H  HA     . MET A 1 21 ? 44.70900  13.15000  5.17200   1.000 60.70251  ?  185 MET A HA     1 
ATOM   279  H  HB2    . MET A 1 21 ? 42.69700  11.49600  6.26200   1.000 56.98267  ?  185 MET A HB2    1 
ATOM   280  H  HB3    . MET A 1 21 ? 42.60900  12.28500  4.88500   1.000 56.98267  ?  185 MET A HB3    1 
ATOM   281  H  HG2    . MET A 1 21 ? 44.58900  10.85000  4.34200   1.000 71.85846  ?  185 MET A HG2    1 
ATOM   282  H  HG3    . MET A 1 21 ? 43.93000  9.89800   5.42200   1.000 71.85846  ?  185 MET A HG3    1 
ATOM   283  H  HE1    . MET A 1 21 ? 42.15600  11.00500  1.55500   1.000 65.00531  ?  185 MET A HE1    1 
ATOM   284  H  HE2    . MET A 1 21 ? 41.96000  11.97500  2.79600   1.000 65.00531  ?  185 MET A HE2    1 
ATOM   285  H  HE3    . MET A 1 21 ? 43.41900  11.68100  2.23900   1.000 65.00531  ?  185 MET A HE3    1 
ATOM   286  N  N      . LYS A 1 22 ? 44.65000  14.65900  7.44900   1.000 48.78249  ?  186 LYS A N      1 
ATOM   287  C  CA     . LYS A 1 22 ? 44.24300  15.78000  8.32900   1.000 56.28073  ?  186 LYS A CA     1 
ATOM   288  C  C      . LYS A 1 22 ? 43.83000  16.93600  7.42800   1.000 54.62026  ?  186 LYS A C      1 
ATOM   289  O  O      . LYS A 1 22 ? 43.17200  17.83900  7.91100   1.000 55.95829  ?  186 LYS A O      1 
ATOM   290  C  CB     . LYS A 1 22 ? 45.37300  16.12100  9.30200   1.000 59.76395  ?  186 LYS A CB     1 
ATOM   291  C  CG     . LYS A 1 22 ? 45.32900  17.49700  9.95500   1.000 69.39185  ?  186 LYS A CG     1 
ATOM   292  C  CD     . LYS A 1 22 ? 44.09800  17.76000  10.79900  1.000 77.70702  ?  186 LYS A CD     1 
ATOM   293  C  CE     . LYS A 1 22 ? 43.59100  19.18200  10.67700  1.000 72.76943  ?  186 LYS A CE     1 
ATOM   294  N  NZ     . LYS A 1 22 ? 43.28500  19.77100  12.00000  1.000 72.23273  ?  186 LYS A NZ     1 
ATOM   295  H  H      . LYS A 1 22 ? 45.50200  14.59100  7.35500   1.000 58.53898  ?  186 LYS A H      1 
ATOM   296  H  HA     . LYS A 1 22 ? 43.46900  15.51100  8.84900   1.000 67.53688  ?  186 LYS A HA     1 
ATOM   297  H  HB2    . LYS A 1 22 ? 45.36400  15.46500  10.01700  1.000 71.71675  ?  186 LYS A HB2    1 
ATOM   298  H  HB3    . LYS A 1 22 ? 46.21400  16.05900  8.82200   1.000 71.71675  ?  186 LYS A HB3    1 
ATOM   299  H  HG2    . LYS A 1 22 ? 46.10300  17.58700  10.53300  1.000 83.27022  ?  186 LYS A HG2    1 
ATOM   300  H  HG3    . LYS A 1 22 ? 45.36600  18.17000  9.25800   1.000 83.27022  ?  186 LYS A HG3    1 
ATOM   301  H  HD2    . LYS A 1 22 ? 43.38700  17.16400  10.51800  1.000 93.24842  ?  186 LYS A HD2    1 
ATOM   302  H  HD3    . LYS A 1 22 ? 44.31500  17.59900  11.73100  1.000 93.24842  ?  186 LYS A HD3    1 
ATOM   303  H  HE2    . LYS A 1 22 ? 44.27000  19.73300  10.25800  1.000 87.32331  ?  186 LYS A HE2    1 
ATOM   304  H  HE3    . LYS A 1 22 ? 42.78000  19.19000  10.14500  1.000 87.32331  ?  186 LYS A HE3    1 
ATOM   305  H  HZ1    . LYS A 1 22 ? 42.99000  20.60500  11.90100  1.000 86.67928  ?  186 LYS A HZ1    1 
ATOM   306  H  HZ2    . LYS A 1 22 ? 42.65900  19.28900  12.41000  1.000 86.67928  ?  186 LYS A HZ2    1 
ATOM   307  H  HZ3    . LYS A 1 22 ? 44.01800  19.78200  12.50500  1.000 86.67928  ?  186 LYS A HZ3    1 
ATOM   308  N  N      . ASP A 1 23 ? 44.21300  16.89000  6.16100   1.000 57.81185  ?  187 ASP A N      1 
ATOM   309  C  CA     . ASP A 1 23 ? 43.82300  17.92100  5.17600   1.000 59.57698  ?  187 ASP A CA     1 
ATOM   310  C  C      . ASP A 1 23 ? 42.40700  17.59500  4.70400   1.000 55.07682  ?  187 ASP A C      1 
ATOM   311  O  O      . ASP A 1 23 ? 41.75100  18.52400  4.24200   1.000 51.72437  ?  187 ASP A O      1 
ATOM   312  C  CB     . ASP A 1 23 ? 44.81400  17.97900  4.01600   1.000 70.84484  ?  187 ASP A CB     1 
ATOM   313  C  CG     . ASP A 1 23 ? 46.22600  18.40200  4.38200   1.000 76.03041  ?  187 ASP A CG     1 
ATOM   314  O  OD1    . ASP A 1 23 ? 46.41600  18.93500  5.49200   1.000 75.89346  ?  187 ASP A OD1    1 
ATOM   315  O  OD2    . ASP A 1 23 ? 47.12600  18.20300  3.54300   1.000 90.41850  -1 187 ASP A OD2    1 
ATOM   316  H  H      . ASP A 1 23 ? 44.70900  16.27300  5.82700   1.000 69.37422  ?  187 ASP A H      1 
ATOM   317  H  HA     . ASP A 1 23 ? 43.80800  18.78900  5.60800   1.000 71.49238  ?  187 ASP A HA     1 
ATOM   318  H  HB2    . ASP A 1 23 ? 44.86900  17.09800  3.61500   1.000 85.01381  ?  187 ASP A HB2    1 
ATOM   319  H  HB3    . ASP A 1 23 ? 44.48200  18.61300  3.36100   1.000 85.01381  ?  187 ASP A HB3    1 
ATOM   320  N  N      . SER A 1 24 ? 41.95700  16.34600  4.84700   1.000 50.32003  ?  188 SER A N      1 
ATOM   321  C  CA     . SER A 1 24 ? 40.62000  15.91500  4.43100   1.000 52.91294  ?  188 SER A CA     1 
ATOM   322  C  C      . SER A 1 24 ? 39.62400  15.78600  5.59300   1.000 48.15472  ?  188 SER A C      1 
ATOM   323  O  O      . SER A 1 24 ? 38.43800  16.00600  5.39300   1.000 38.82610  ?  188 SER A O      1 
ATOM   324  C  CB     . SER A 1 24 ? 40.69400  14.56300  3.68000   1.000 47.84898  ?  188 SER A CB     1 
ATOM   325  O  OG     . SER A 1 24 ? 41.53200  14.62000  2.54000   1.000 57.09623  ?  188 SER A OG     1 
ATOM   326  H  H      . SER A 1 24 ? 42.42200  15.71000  5.19100   1.000 60.38404  ?  188 SER A H      1 
ATOM   327  H  HA     . SER A 1 24 ? 40.26000  16.57200  3.81700   1.000 63.49552  ?  188 SER A HA     1 
ATOM   328  H  HB2    . SER A 1 24 ? 41.04000  13.89000  4.28600   1.000 57.41877  ?  188 SER A HB2    1 
ATOM   329  H  HB3    . SER A 1 24 ? 39.80000  14.31700  3.39600   1.000 57.41877  ?  188 SER A HB3    1 
ATOM   330  H  HG     . SER A 1 24 ? 41.20500  15.14500  1.97200   1.000 68.51547  ?  188 SER A HG     1 
ATOM   331  N  N      . ILE A 1 25 ? 40.05500  15.44700  6.79800   1.000 46.93951  ?  189 ILE A N      1 
ATOM   332  C  CA     . ILE A 1 25 ? 39.11900  15.24300  7.90600   1.000 44.14253  ?  189 ILE A CA     1 
ATOM   333  C  C      . ILE A 1 25 ? 39.82400  15.53900  9.22600   1.000 44.67216  ?  189 ILE A C      1 
ATOM   334  O  O      . ILE A 1 25 ? 40.99000  15.17800  9.39200   1.000 41.90100  ?  189 ILE A O      1 
ATOM   335  C  CB     . ILE A 1 25 ? 38.60200  13.79900  7.89300   1.000 39.15827  ?  189 ILE A CB     1 
ATOM   336  C  CG1    . ILE A 1 25 ? 37.39800  13.67100  8.82600   1.000 40.83764  ?  189 ILE A CG1    1 
ATOM   337  C  CG2    . ILE A 1 25 ? 39.76200  12.85100  8.22000   1.000 41.50969  ?  189 ILE A CG2    1 
ATOM   338  C  CD1    . ILE A 1 25 ? 36.95100  12.25300  9.07100   1.000 37.95643  ?  189 ILE A CD1    1 
ATOM   339  H  H      . ILE A 1 25 ? 40.88100  15.32800  7.00600   1.000 56.32741  ?  189 ILE A H      1 
ATOM   340  H  HA     . ILE A 1 25 ? 38.36500  15.84500  7.81400   1.000 52.97104  ?  189 ILE A HA     1 
ATOM   341  H  HB     . ILE A 1 25 ? 38.30100  13.59900  6.99300   1.000 46.98992  ?  189 ILE A HB     1 
ATOM   342  H  HG12   . ILE A 1 25 ? 37.62300  14.05800  9.68600   1.000 49.00517  ?  189 ILE A HG12   1 
ATOM   343  H  HG13   . ILE A 1 25 ? 36.65100  14.15200  8.43700   1.000 49.00517  ?  189 ILE A HG13   1 
ATOM   344  H  HG21   . ILE A 1 25 ? 39.50900  11.94900  7.96800   1.000 49.81163  ?  189 ILE A HG21   1 
ATOM   345  H  HG22   . ILE A 1 25 ? 40.54500  13.12300  7.72000   1.000 49.81163  ?  189 ILE A HG22   1 
ATOM   346  H  HG23   . ILE A 1 25 ? 39.94700  12.88700  9.17100   1.000 49.81163  ?  189 ILE A HG23   1 
ATOM   347  H  HD11   . ILE A 1 25 ? 36.10800  12.26400  9.54700   1.000 45.54772  ?  189 ILE A HD11   1 
ATOM   348  H  HD12   . ILE A 1 25 ? 36.84200  11.80600  8.21700   1.000 45.54772  ?  189 ILE A HD12   1 
ATOM   349  H  HD13   . ILE A 1 25 ? 37.62400  11.79600  9.60000   1.000 45.54772  ?  189 ILE A HD13   1 
ATOM   350  N  N      . TRP A 1 26 ? 39.11100  16.17000  10.17400  1.000 40.39942  ?  190 TRP A N      1 
ATOM   351  C  CA     . TRP A 1 26 ? 39.69700  16.50600  11.47900  1.000 50.02190  ?  190 TRP A CA     1 
ATOM   352  C  C      . TRP A 1 26 ? 38.63900  16.55200  12.58500  1.000 47.82464  ?  190 TRP A C      1 
ATOM   353  O  O      . TRP A 1 26 ? 37.44300  16.74800  12.33700  1.000 37.33585  ?  190 TRP A O      1 
ATOM   354  C  CB     . TRP A 1 26 ? 40.42600  17.86800  11.44100  1.000 49.06390  ?  190 TRP A CB     1 
ATOM   355  C  CG     . TRP A 1 26 ? 39.50600  18.95400  10.91000  1.000 49.92690  ?  190 TRP A CG     1 
ATOM   356  C  CD1    . TRP A 1 26 ? 38.53900  19.63300  11.61000  1.000 53.45050  ?  190 TRP A CD1    1 
ATOM   357  C  CD2    . TRP A 1 26 ? 39.42900  19.43600  9.56100   1.000 51.84542  ?  190 TRP A CD2    1 
ATOM   358  N  NE1    . TRP A 1 26 ? 37.87700  20.50900  10.77900  1.000 54.01402  ?  190 TRP A NE1    1 
ATOM   359  C  CE2    . TRP A 1 26 ? 38.41000  20.41400  9.52100   1.000 51.20066  ?  190 TRP A CE2    1 
ATOM   360  C  CE3    . TRP A 1 26 ? 40.13600  19.14800  8.38700   1.000 56.83313  ?  190 TRP A CE3    1 
ATOM   361  C  CZ2    . TRP A 1 26 ? 38.08500  21.11000  8.36200   1.000 50.80265  ?  190 TRP A CZ2    1 
ATOM   362  C  CZ3    . TRP A 1 26 ? 39.80100  19.84100  7.21700   1.000 55.92694  ?  190 TRP A CZ3    1 
ATOM   363  C  CH2    . TRP A 1 26 ? 38.77900  20.80800  7.22500   1.000 54.31765  ?  190 TRP A CH2    1 
ATOM   364  H  H      . TRP A 1 26 ? 38.29100  16.41200  10.08500  1.000 48.47930  ?  190 TRP A H      1 
ATOM   365  H  HA     . TRP A 1 26 ? 40.34700  15.82600  11.71600  1.000 60.02628  ?  190 TRP A HA     1 
ATOM   366  H  HB2    . TRP A 1 26 ? 40.70400  18.11200  12.33800  1.000 58.87668  ?  190 TRP A HB2    1 
ATOM   367  H  HB3    . TRP A 1 26 ? 41.19400  17.80200  10.85300  1.000 58.87668  ?  190 TRP A HB3    1 
ATOM   368  H  HD1    . TRP A 1 26 ? 38.34900  19.50900  12.51200  1.000 64.14060  ?  190 TRP A HD1    1 
ATOM   369  H  HE1    . TRP A 1 26 ? 37.24500  21.04200  11.01600  1.000 64.81682  ?  190 TRP A HE1    1 
ATOM   370  H  HE3    . TRP A 1 26 ? 40.81100  18.50800  8.38400   1.000 68.19976  ?  190 TRP A HE3    1 
ATOM   371  H  HZ2    . TRP A 1 26 ? 37.40800  21.74800  8.35800   1.000 60.96318  ?  190 TRP A HZ2    1 
ATOM   372  H  HZ3    . TRP A 1 26 ? 40.26000  19.66200  6.42900   1.000 67.11233  ?  190 TRP A HZ3    1 
ATOM   373  H  HH2    . TRP A 1 26 ? 38.57600  21.25800  6.43700   1.000 65.18119  ?  190 TRP A HH2    1 
ATOM   374  N  N      . TRP A 1 27 ? 39.10300  16.41300  13.82800  1.000 42.48763  ?  191 TRP A N      1 
ATOM   375  C  CA     . TRP A 1 27 ? 38.21100  16.63900  14.95900  1.000 41.80756  ?  191 TRP A CA     1 
ATOM   376  C  C      . TRP A 1 27 ? 37.80700  18.11100  15.02500  1.000 43.81519  ?  191 TRP A C      1 
ATOM   377  O  O      . TRP A 1 27 ? 38.59300  19.01200  14.72100  1.000 43.67576  ?  191 TRP A O      1 
ATOM   378  C  CB     . TRP A 1 27 ? 38.84700  16.22500  16.28400  1.000 44.78763  ?  191 TRP A CB     1 
ATOM   379  C  CG     . TRP A 1 27 ? 39.14900  14.80000  16.43100  1.000 40.10686  ?  191 TRP A CG     1 
ATOM   380  C  CD1    . TRP A 1 27 ? 40.38100  14.24200  16.54500  1.000 39.07936  ?  191 TRP A CD1    1 
ATOM   381  C  CD2    . TRP A 1 27 ? 38.20800  13.72700  16.52800  1.000 38.81119  ?  191 TRP A CD2    1 
ATOM   382  N  NE1    . TRP A 1 27 ? 40.27300  12.89000  16.70400  1.000 42.26636  ?  191 TRP A NE1    1 
ATOM   383  C  CE2    . TRP A 1 27 ? 38.94900  12.54400  16.69600  1.000 36.34509  ?  191 TRP A CE2    1 
ATOM   384  C  CE3    . TRP A 1 27 ? 36.82800  13.65300  16.48800  1.000 41.28197  ?  191 TRP A CE3    1 
ATOM   385  C  CZ2    . TRP A 1 27 ? 38.35600  11.29700  16.78600  1.000 37.35170  ?  191 TRP A CZ2    1 
ATOM   386  C  CZ3    . TRP A 1 27 ? 36.23700  12.40700  16.60400  1.000 42.17983  ?  191 TRP A CZ3    1 
ATOM   387  C  CH2    . TRP A 1 27 ? 37.00400  11.24100  16.75900  1.000 38.88564  ?  191 TRP A CH2    1 
ATOM   388  H  H      . TRP A 1 27 ? 39.90800  16.19500  14.03700  1.000 50.98516  ?  191 TRP A H      1 
ATOM   389  H  HA     . TRP A 1 27 ? 37.40600  16.11200  14.83600  1.000 50.16908  ?  191 TRP A HA     1 
ATOM   390  H  HB2    . TRP A 1 27 ? 39.68100  16.71000  16.38700  1.000 53.74516  ?  191 TRP A HB2    1 
ATOM   391  H  HB3    . TRP A 1 27 ? 38.24200  16.46800  17.00200  1.000 53.74516  ?  191 TRP A HB3    1 
ATOM   392  H  HD1    . TRP A 1 27 ? 41.18200  14.71400  16.52900  1.000 46.89523  ?  191 TRP A HD1    1 
ATOM   393  H  HE1    . TRP A 1 27 ? 40.93200  12.34200  16.78000  1.000 50.71963  ?  191 TRP A HE1    1 
ATOM   394  H  HE3    . TRP A 1 27 ? 36.31100  14.41900  16.38300  1.000 49.53836  ?  191 TRP A HE3    1 
ATOM   395  H  HZ2    . TRP A 1 27 ? 38.86700  10.52900  16.90200  1.000 44.82204  ?  191 TRP A HZ2    1 
ATOM   396  H  HZ3    . TRP A 1 27 ? 35.31000  12.34000  16.57500  1.000 50.61579  ?  191 TRP A HZ3    1 
ATOM   397  H  HH2    . TRP A 1 27 ? 36.57800  10.41800  16.83200  1.000 46.66276  ?  191 TRP A HH2    1 
ATOM   398  N  N      . VAL A 1 28 ? 36.53800  18.32700  15.33300  1.000 44.82779  ?  192 VAL A N      1 
ATOM   399  C  CA     . VAL A 1 28 ? 36.04500  19.60600  15.81400  1.000 47.61133  ?  192 VAL A CA     1 
ATOM   400  C  C      . VAL A 1 28 ? 36.06100  19.62200  17.34000  1.000 55.48733  ?  192 VAL A C      1 
ATOM   401  O  O      . VAL A 1 28 ? 36.49000  20.60700  17.94200  1.000 58.28581  ?  192 VAL A O      1 
ATOM   402  C  CB     . VAL A 1 28 ? 34.62100  19.88500  15.27900  1.000 52.05451  ?  192 VAL A CB     1 
ATOM   403  C  CG1    . VAL A 1 28 ? 34.18300  21.28900  15.64100  1.000 48.27707  ?  192 VAL A CG1    1 
ATOM   404  C  CG2    . VAL A 1 28 ? 34.51500  19.67400  13.76800  1.000 44.48266  ?  192 VAL A CG2    1 
ATOM   405  H  H      . VAL A 1 28 ? 35.92400  17.72800  15.26900  1.000 53.79335  ?  192 VAL A H      1 
ATOM   406  H  HA     . VAL A 1 28 ? 36.63000  20.31300  15.49800  1.000 57.13359  ?  192 VAL A HA     1 
ATOM   407  H  HB     . VAL A 1 28 ? 34.00500  19.26800  15.70400  1.000 62.46542  ?  192 VAL A HB     1 
ATOM   408  H  HG11   . VAL A 1 28 ? 33.33500  21.47600  15.20800  1.000 57.93248  ?  192 VAL A HG11   1 
ATOM   409  H  HG12   . VAL A 1 28 ? 34.08200  21.35200  16.60400  1.000 57.93248  ?  192 VAL A HG12   1 
ATOM   410  H  HG13   . VAL A 1 28 ? 34.85600  21.91800  15.33500  1.000 57.93248  ?  192 VAL A HG13   1 
ATOM   411  H  HG21   . VAL A 1 28 ? 33.62700  19.93200  13.47500  1.000 53.37919  ?  192 VAL A HG21   1 
ATOM   412  H  HG22   . VAL A 1 28 ? 35.18200  20.22200  13.32600  1.000 53.37919  ?  192 VAL A HG22   1 
ATOM   413  H  HG23   . VAL A 1 28 ? 34.67000  18.73800  13.56700  1.000 53.37919  ?  192 VAL A HG23   1 
ATOM   414  N  N      . ASP A 1 29 ? 35.59000  18.53200  17.96800  1.000 56.31487  ?  193 ASP A N      1 
ATOM   415  C  CA     . ASP A 1 29 ? 35.75100  18.32300  19.41200  1.000 52.48809  ?  193 ASP A CA     1 
ATOM   416  C  C      . ASP A 1 29 ? 35.99400  16.83700  19.63400  1.000 53.76892  ?  193 ASP A C      1 
ATOM   417  O  O      . ASP A 1 29 ? 35.06100  16.02800  19.50000  1.000 55.80234  ?  193 ASP A O      1 
ATOM   418  C  CB     . ASP A 1 29 ? 34.55500  18.80100  20.24500  1.000 66.62903  ?  193 ASP A CB     1 
ATOM   419  C  CG     . ASP A 1 29 ? 34.83500  18.73100  21.80500  1.000 68.76441  ?  193 ASP A CG     1 
ATOM   420  O  OD1    . ASP A 1 29 ? 35.49400  17.76700  22.27000  1.000 61.61500  ?  193 ASP A OD1    1 
ATOM   421  O  OD2    . ASP A 1 29 ? 34.40600  19.63700  22.57000  1.000 77.84421  -1 193 ASP A OD2    1 
ATOM   422  H  H      . ASP A 1 29 ? 35.17000  17.89400  17.57200  1.000 67.57784  ?  193 ASP A H      1 
ATOM   423  H  HA     . ASP A 1 29 ? 36.53700  18.80400  19.71500  1.000 62.98571  ?  193 ASP A HA     1 
ATOM   424  H  HB2    . ASP A 1 29 ? 34.35800  19.72300  20.01600  1.000 79.95484  ?  193 ASP A HB2    1 
ATOM   425  H  HB3    . ASP A 1 29 ? 33.78900  18.23900  20.05100  1.000 79.95484  ?  193 ASP A HB3    1 
ATOM   426  N  N      . LYS A 1 30 ? 37.25000  16.50100  19.95900  1.000 50.95116  ?  194 LYS A N      1 
ATOM   427  C  CA     . LYS A 1 30 ? 37.67500  15.10800  20.05400  1.000 55.00726  ?  194 LYS A CA     1 
ATOM   428  C  C      . LYS A 1 30 ? 36.90900  14.37900  21.14900  1.000 57.29356  ?  194 LYS A C      1 
ATOM   429  O  O      . LYS A 1 30 ? 36.40800  13.26900  20.93800  1.000 51.77029  ?  194 LYS A O      1 
ATOM   430  C  CB     . LYS A 1 30 ? 39.18500  15.04100  20.32800  1.000 56.10776  ?  194 LYS A CB     1 
ATOM   431  C  CG     . LYS A 1 30 ? 39.72300  13.62200  20.53700  1.000 52.78814  ?  194 LYS A CG     1 
ATOM   432  C  CD     . LYS A 1 30 ? 41.21500  13.62100  20.87000  1.000 61.21550  ?  194 LYS A CD     1 
ATOM   433  C  CE     . LYS A 1 30 ? 41.86700  12.28000  20.52200  1.000 62.64982  ?  194 LYS A CE     1 
ATOM   434  N  NZ     . LYS A 1 30 ? 43.35000  12.28900  20.74100  1.000 63.23015  ?  194 LYS A NZ     1 
ATOM   435  H  H      . LYS A 1 30 ? 37.87400  17.06800  20.12900  1.000 61.14140  ?  194 LYS A H      1 
ATOM   436  H  HA     . LYS A 1 30 ? 37.49900  14.66200  19.21100  1.000 66.00871  ?  194 LYS A HA     1 
ATOM   437  H  HB2    . LYS A 1 30 ? 39.65600  15.42700  19.57300  1.000 67.32931  ?  194 LYS A HB2    1 
ATOM   438  H  HB3    . LYS A 1 30 ? 39.37900  15.55100  21.13000  1.000 67.32931  ?  194 LYS A HB3    1 
ATOM   439  H  HG2    . LYS A 1 30 ? 39.25500  13.20200  21.27500  1.000 63.34577  ?  194 LYS A HG2    1 
ATOM   440  H  HG3    . LYS A 1 30 ? 39.59400  13.10900  19.72400  1.000 63.34577  ?  194 LYS A HG3    1 
ATOM   441  H  HD2    . LYS A 1 30 ? 41.65800  14.31600  20.35800  1.000 73.45860  ?  194 LYS A HD2    1 
ATOM   442  H  HD3    . LYS A 1 30 ? 41.33100  13.77800  21.82000  1.000 73.45860  ?  194 LYS A HD3    1 
ATOM   443  H  HE2    . LYS A 1 30 ? 41.48400  11.58700  21.08200  1.000 75.17978  ?  194 LYS A HE2    1 
ATOM   444  H  HE3    . LYS A 1 30 ? 41.70200  12.08100  19.58700  1.000 75.17978  ?  194 LYS A HE3    1 
ATOM   445  H  HZ1    . LYS A 1 30 ? 43.69300  11.49600  20.52900  1.000 75.87618  ?  194 LYS A HZ1    1 
ATOM   446  H  HZ2    . LYS A 1 30 ? 43.72900  12.91300  20.23200  1.000 75.87618  ?  194 LYS A HZ2    1 
ATOM   447  H  HZ3    . LYS A 1 30 ? 43.53000  12.46300  21.59500  1.000 75.87618  ?  194 LYS A HZ3    1 
ATOM   448  N  N      . ASP A 1 31 ? 36.83600  14.99000  22.33700  1.000 62.31128  ?  195 ASP A N      1 
ATOM   449  C  CA     . ASP A 1 31 ? 36.16400  14.39400  23.49400  1.000 69.16423  ?  195 ASP A CA     1 
ATOM   450  C  C      . ASP A 1 31 ? 34.65700  14.21800  23.28300  1.000 63.96761  ?  195 ASP A C      1 
ATOM   451  O  O      . ASP A 1 31 ? 34.04200  13.35800  23.93400  1.000 65.02797  ?  195 ASP A O      1 
ATOM   452  C  CB     . ASP A 1 31 ? 36.42200  15.26200  24.74300  1.000 68.14481  ?  195 ASP A CB     1 
ATOM   453  C  CG     . ASP A 1 31 ? 37.88300  15.68200  24.88200  1.000 74.50814  ?  195 ASP A CG     1 
ATOM   454  O  OD1    . ASP A 1 31 ? 38.78200  14.80600  24.86300  1.000 75.11793  ?  195 ASP A OD1    1 
ATOM   455  O  OD2    . ASP A 1 31 ? 38.12900  16.90300  25.00900  1.000 77.98193  -1 195 ASP A OD2    1 
ATOM   456  H  H      . ASP A 1 31 ? 37.17100  15.76600  22.49400  1.000 74.77354  ?  195 ASP A H      1 
ATOM   457  H  HA     . ASP A 1 31 ? 36.54400  13.51700  23.65800  1.000 82.99707  ?  195 ASP A HA     1 
ATOM   458  H  HB2    . ASP A 1 31 ? 35.87800  16.06400  24.69400  1.000 81.77378  ?  195 ASP A HB2    1 
ATOM   459  H  HB3    . ASP A 1 31 ? 36.19300  14.74900  25.53200  1.000 81.77378  ?  195 ASP A HB3    1 
ATOM   460  N  N      . LYS A 1 32 ? 34.04800  15.00700  22.39500  1.000 61.29227  ?  196 LYS A N      1 
ATOM   461  C  CA     . LYS A 1 32 ? 32.65200  14.81500  22.00600  1.000 61.20927  ?  196 LYS A CA     1 
ATOM   462  C  C      . LYS A 1 32 ? 32.47700  14.00900  20.71600  1.000 54.87692  ?  196 LYS A C      1 
ATOM   463  O  O      . LYS A 1 32 ? 31.34800  13.79100  20.29100  1.000 56.97747  ?  196 LYS A O      1 
ATOM   464  C  CB     . LYS A 1 32 ? 31.96000  16.18200  21.87300  1.000 65.08313  ?  196 LYS A CB     1 
ATOM   465  C  CG     . LYS A 1 32 ? 32.00600  16.97000  23.17900  1.000 68.72574  ?  196 LYS A CG     1 
ATOM   466  C  CD     . LYS A 1 32 ? 31.07700  18.17300  23.21900  1.000 70.79640  ?  196 LYS A CD     1 
ATOM   467  C  CE     . LYS A 1 32 ? 30.69200  18.54100  24.69300  1.000 78.43681  ?  196 LYS A CE     1 
ATOM   468  N  NZ     . LYS A 1 32 ? 29.65800  17.64600  25.31700  1.000 75.23219  ?  196 LYS A NZ     1 
ATOM   469  H  H      . LYS A 1 32 ? 34.42900  15.66900  21.99900  1.000 73.55073  ?  196 LYS A H      1 
ATOM   470  H  HA     . LYS A 1 32 ? 32.19900  14.33000  22.71300  1.000 73.45112  ?  196 LYS A HA     1 
ATOM   471  H  HB2    . LYS A 1 32 ? 32.41000  16.70200  21.18900  1.000 78.09976  ?  196 LYS A HB2    1 
ATOM   472  H  HB3    . LYS A 1 32 ? 31.03000  16.04700  21.63300  1.000 78.09976  ?  196 LYS A HB3    1 
ATOM   473  H  HG2    . LYS A 1 32 ? 31.75500  16.38000  23.90700  1.000 82.47089  ?  196 LYS A HG2    1 
ATOM   474  H  HG3    . LYS A 1 32 ? 32.91100  17.29200  23.31600  1.000 82.47089  ?  196 LYS A HG3    1 
ATOM   475  H  HD2    . LYS A 1 32 ? 31.52300  18.93700  22.82000  1.000 84.95568  ?  196 LYS A HD2    1 
ATOM   476  H  HD3    . LYS A 1 32 ? 30.26300  17.96700  22.73400  1.000 84.95568  ?  196 LYS A HD3    1 
ATOM   477  H  HE2    . LYS A 1 32 ? 31.49000  18.49500  25.24200  1.000 94.12417  ?  196 LYS A HE2    1 
ATOM   478  H  HE3    . LYS A 1 32 ? 30.34100  19.44500  24.70400  1.000 94.12417  ?  196 LYS A HE3    1 
ATOM   479  H  HZ1    . LYS A 1 32 ? 29.48900  17.91200  26.14900  1.000 90.27863  ?  196 LYS A HZ1    1 
ATOM   480  H  HZ2    . LYS A 1 32 ? 28.90400  17.67700  24.84400  1.000 90.27863  ?  196 LYS A HZ2    1 
ATOM   481  H  HZ3    . LYS A 1 32 ? 29.95400  16.80700  25.33600  1.000 90.27863  ?  196 LYS A HZ3    1 
ATOM   482  N  N      . GLY A 1 33 ? 33.55400  13.54300  20.09900  1.000 48.90171  ?  197 GLY A N      1 
ATOM   483  C  CA     . GLY A 1 33 ? 33.42900  12.73800  18.89200  1.000 50.73956  ?  197 GLY A CA     1 
ATOM   484  C  C      . GLY A 1 33 ? 33.05200  13.46800  17.61200  1.000 41.89037  ?  197 GLY A C      1 
ATOM   485  O  O      . GLY A 1 33 ? 32.70600  12.80300  16.64000  1.000 40.43965  ?  197 GLY A O      1 
ATOM   486  H  H      . GLY A 1 33 ? 34.36400  13.67700  20.35600  1.000 58.68206  ?  197 GLY A H      1 
ATOM   487  H  HA2    . GLY A 1 33 ? 34.27400  12.28900  18.73300  1.000 60.88747  ?  197 GLY A HA2    1 
ATOM   488  H  HA3    . GLY A 1 33 ? 32.75700  12.05600  19.04600  1.000 60.88747  ?  197 GLY A HA3    1 
ATOM   489  N  N      . THR A 1 34 ? 33.07700  14.79700  17.58700  1.000 43.30478  ?  198 THR A N      1 
ATOM   490  C  CA     . THR A 1 34 ? 32.55200  15.54000  16.45900  1.000 44.13512  ?  198 THR A CA     1 
ATOM   491  C  C      . THR A 1 34 ? 33.70000  15.84000  15.50500  1.000 44.10686  ?  198 THR A C      1 
ATOM   492  O  O      . THR A 1 34 ? 34.75000  16.34800  15.93200  1.000 43.18775  ?  198 THR A O      1 
ATOM   493  C  CB     . THR A 1 34 ? 31.89100  16.85400  16.88000  1.000 45.41124  ?  198 THR A CB     1 
ATOM   494  O  OG1    . THR A 1 34 ? 32.86800  17.64300  17.53700  1.000 47.00021  ?  198 THR A OG1    1 
ATOM   495  C  CG2    . THR A 1 34 ? 30.72200  16.65600  17.85100  1.000 50.12457  ?  198 THR A CG2    1 
ATOM   496  H  H      . THR A 1 34 ? 33.39500  15.29000  18.21600  1.000 51.96574  ?  198 THR A H      1 
ATOM   497  H  HA     . THR A 1 34 ? 31.89500  15.00100  15.99300  1.000 52.96214  ?  198 THR A HA     1 
ATOM   498  H  HB     . THR A 1 34 ? 31.56700  17.32300  16.09500  1.000 54.49349  ?  198 THR A HB     1 
ATOM   499  H  HG1    . THR A 1 34 ? 32.53200  18.37300  17.78000  1.000 56.40025  ?  198 THR A HG1    1 
ATOM   500  H  HG21   . THR A 1 34 ? 30.36200  17.51700  18.11500  1.000 60.14948  ?  198 THR A HG21   1 
ATOM   501  H  HG22   . THR A 1 34 ? 30.02100  16.13900  17.42400  1.000 60.14948  ?  198 THR A HG22   1 
ATOM   502  H  HG23   . THR A 1 34 ? 31.02500  16.18500  18.64300  1.000 60.14948  ?  198 THR A HG23   1 
ATOM   503  N  N      . PHE A 1 35 ? 33.46100  15.57100  14.22300  1.000 40.10357  ?  199 PHE A N      1 
ATOM   504  C  CA     . PHE A 1 35 ? 34.47100  15.71100  13.19400  1.000 38.32655  ?  199 PHE A CA     1 
ATOM   505  C  C      . PHE A 1 35 ? 33.87200  16.29500  11.92500  1.000 41.40870  ?  199 PHE A C      1 
ATOM   506  O  O      . PHE A 1 35 ? 32.64500  16.33900  11.73400  1.000 37.78435  ?  199 PHE A O      1 
ATOM   507  C  CB     . PHE A 1 35 ? 35.10500  14.36500  12.89700  1.000 38.02275  ?  199 PHE A CB     1 
ATOM   508  C  CG     . PHE A 1 35 ? 34.14000  13.33900  12.32500  1.000 38.73150  ?  199 PHE A CG     1 
ATOM   509  C  CD1    . PHE A 1 35 ? 33.44300  12.52300  13.13600  1.000 36.44716  ?  199 PHE A CD1    1 
ATOM   510  C  CD2    . PHE A 1 35 ? 33.99600  13.16700  10.97300  1.000 35.92417  ?  199 PHE A CD2    1 
ATOM   511  C  CE1    . PHE A 1 35 ? 32.60600  11.58300  12.64000  1.000 35.56559  ?  199 PHE A CE1    1 
ATOM   512  C  CE2    . PHE A 1 35 ? 33.14000  12.20200  10.46500  1.000 29.79299  ?  199 PHE A CE2    1 
ATOM   513  C  CZ     . PHE A 1 35 ? 32.47700  11.41100  11.28400  1.000 31.17767  ?  199 PHE A CZ     1 
ATOM   514  H  H      . PHE A 1 35 ? 32.70200  15.30000  13.92400  1.000 48.12429  ?  199 PHE A H      1 
ATOM   515  H  HA     . PHE A 1 35 ? 35.16600  16.31200  13.50600  1.000 45.99186  ?  199 PHE A HA     1 
ATOM   516  H  HB2    . PHE A 1 35 ? 35.81800  14.49200  12.25200  1.000 45.62730  ?  199 PHE A HB2    1 
ATOM   517  H  HB3    . PHE A 1 35 ? 35.46800  14.00300  13.72000  1.000 45.62730  ?  199 PHE A HB3    1 
ATOM   518  H  HD1    . PHE A 1 35 ? 33.53300  12.61200  14.05700  1.000 43.73659  ?  199 PHE A HD1    1 
ATOM   519  H  HD2    . PHE A 1 35 ? 34.47600  13.70800  10.38800  1.000 43.10901  ?  199 PHE A HD2    1 
ATOM   520  H  HE1    . PHE A 1 35 ? 32.13200  11.03400  13.22200  1.000 42.67870  ?  199 PHE A HE1    1 
ATOM   521  H  HE2    . PHE A 1 35 ? 33.04900  12.10000  9.54500   1.000 35.75158  ?  199 PHE A HE2    1 
ATOM   522  H  HZ     . PHE A 1 35 ? 31.88800  10.77500  10.94700  1.000 37.41320  ?  199 PHE A HZ     1 
ATOM   523  N  N      . GLN A 1 36 ? 34.77000  16.70300  11.03400  1.000 38.78313  ?  200 GLN A N      1 
ATOM   524  C  CA     . GLN A 1 36 ? 34.40600  17.55400  9.92000   1.000 44.94075  ?  200 GLN A CA     1 
ATOM   525  C  C      . GLN A 1 36 ? 35.24600  17.19400  8.70900   1.000 44.01986  ?  200 GLN A C      1 
ATOM   526  O  O      . GLN A 1 36 ? 36.44300  16.91300  8.83000   1.000 42.50005  ?  200 GLN A O      1 
ATOM   527  C  CB     . GLN A 1 36 ? 34.60900  19.01700  10.27100  1.000 43.40187  ?  200 GLN A CB     1 
ATOM   528  C  CG     . GLN A 1 36 ? 34.26500  19.98400  9.18000   1.000 49.88235  ?  200 GLN A CG     1 
ATOM   529  C  CD     . GLN A 1 36 ? 34.39200  21.40600  9.66100   1.000 52.70897  ?  200 GLN A CD     1 
ATOM   530  O  OE1    . GLN A 1 36 ? 35.44800  21.82100  10.14500  1.000 53.07852  ?  200 GLN A OE1    1 
ATOM   531  N  NE2    . GLN A 1 36 ? 33.30200  22.15400  9.55900   1.000 54.48709  ?  200 GLN A NE2    1 
ATOM   532  H  H      . GLN A 1 36 ? 35.60400  16.49600  11.05700  1.000 46.53975  ?  200 GLN A H      1 
ATOM   533  H  HA     . GLN A 1 36 ? 33.47300  17.41700  9.70100   1.000 53.92890  ?  200 GLN A HA     1 
ATOM   534  H  HB2    . GLN A 1 36 ? 34.05300  19.23000  11.03600  1.000 52.08224  ?  200 GLN A HB2    1 
ATOM   535  H  HB3    . GLN A 1 36 ? 35.54200  19.15300  10.49900  1.000 52.08224  ?  200 GLN A HB3    1 
ATOM   536  H  HG2    . GLN A 1 36 ? 34.87300  19.86100  8.43500   1.000 59.85882  ?  200 GLN A HG2    1 
ATOM   537  H  HG3    . GLN A 1 36 ? 33.34900  19.83700  8.89600   1.000 59.85882  ?  200 GLN A HG3    1 
ATOM   538  H  HE21   . GLN A 1 36 ? 32.58400  21.82400  9.22000   1.000 65.38451  ?  200 GLN A HE21   1 
ATOM   539  H  HE22   . GLN A 1 36 ? 33.31700  22.97300  9.82100   1.000 65.38451  ?  200 GLN A HE22   1 
ATOM   540  N  N      . PHE A 1 37 ? 34.61200  17.22900  7.54000   1.000 42.59486  ?  201 PHE A N      1 
ATOM   541  C  CA     . PHE A 1 37 ? 35.31300  17.03100  6.28200   1.000 43.03813  ?  201 PHE A CA     1 
ATOM   542  C  C      . PHE A 1 37 ? 35.71900  18.38600  5.73000   1.000 44.07220  ?  201 PHE A C      1 
ATOM   543  O  O      . PHE A 1 37 ? 35.05700  19.40200  5.96300   1.000 44.52454  ?  201 PHE A O      1 
ATOM   544  C  CB     . PHE A 1 37 ? 34.45500  16.25400  5.25000   1.000 42.17229  ?  201 PHE A CB     1 
ATOM   545  C  CG     . PHE A 1 37 ? 34.16600  14.83600  5.67100   1.000 38.09128  ?  201 PHE A CG     1 
ATOM   546  C  CD1    . PHE A 1 37 ? 35.05300  13.82800  5.39500   1.000 35.20798  ?  201 PHE A CD1    1 
ATOM   547  C  CD2    . PHE A 1 37 ? 33.03500  14.53400  6.37600   1.000 36.65782  ?  201 PHE A CD2    1 
ATOM   548  C  CE1    . PHE A 1 37 ? 34.82300  12.54400  5.80000   1.000 29.60620  ?  201 PHE A CE1    1 
ATOM   549  C  CE2    . PHE A 1 37 ? 32.80000  13.24900  6.78000   1.000 32.72272  ?  201 PHE A CE2    1 
ATOM   550  C  CZ     . PHE A 1 37 ? 33.68800  12.24600  6.48600   1.000 35.95724  ?  201 PHE A CZ     1 
ATOM   551  H  H      . PHE A 1 37 ? 33.76800  17.36700  7.45100   1.000 51.11384  ?  201 PHE A H      1 
ATOM   552  H  HA     . PHE A 1 37 ? 36.12000  16.51900  6.44500   1.000 51.64576  ?  201 PHE A HA     1 
ATOM   553  H  HB2    . PHE A 1 37 ? 33.60700  16.71100  5.13700   1.000 50.60675  ?  201 PHE A HB2    1 
ATOM   554  H  HB3    . PHE A 1 37 ? 34.93000  16.22400  4.40500   1.000 50.60675  ?  201 PHE A HB3    1 
ATOM   555  H  HD1    . PHE A 1 37 ? 35.83200  14.02400  4.92600   1.000 42.24958  ?  201 PHE A HD1    1 
ATOM   556  H  HD2    . PHE A 1 37 ? 32.42400  15.20400  6.58200   1.000 43.98938  ?  201 PHE A HD2    1 
ATOM   557  H  HE1    . PHE A 1 37 ? 35.43300  11.87300  5.59300   1.000 35.52744  ?  201 PHE A HE1    1 
ATOM   558  H  HE2    . PHE A 1 37 ? 32.02300  13.05100  7.25000   1.000 39.26726  ?  201 PHE A HE2    1 
ATOM   559  H  HZ     . PHE A 1 37 ? 33.52000  11.37400  6.76000   1.000 43.14869  ?  201 PHE A HZ     1 
ATOM   560  N  N      . SER A 1 38 ? 36.85800  18.38500  5.04800   1.000 45.95565  ?  202 SER A N      1 
ATOM   561  C  CA     . SER A 1 38 ? 37.32000  19.52500  4.27400   1.000 50.94461  ?  202 SER A CA     1 
ATOM   562  C  C      . SER A 1 38 ? 36.47200  19.72800  3.02100   1.000 50.41546  ?  202 SER A C      1 
ATOM   563  O  O      . SER A 1 38 ? 36.20400  18.78000  2.27400   1.000 46.69893  ?  202 SER A O      1 
ATOM   564  C  CB     . SER A 1 38 ? 38.76700  19.29200  3.84200   1.000 50.42092  ?  202 SER A CB     1 
ATOM   565  O  OG     . SER A 1 38 ? 39.03300  20.01100  2.65400   1.000 54.27509  ?  202 SER A OG     1 
ATOM   566  H  H      . SER A 1 38 ? 37.39500  17.71400  5.02000   1.000 55.14679  ?  202 SER A H      1 
ATOM   567  H  HA     . SER A 1 38 ? 37.27900  20.32900  4.81400   1.000 61.13353  ?  202 SER A HA     1 
ATOM   568  H  HB2    . SER A 1 38 ? 39.36400  19.60100  4.53900   1.000 60.50510  ?  202 SER A HB2    1 
ATOM   569  H  HB3    . SER A 1 38 ? 38.90300  18.34600  3.67800   1.000 60.50510  ?  202 SER A HB3    1 
ATOM   570  H  HG     . SER A 1 38 ? 39.84100  19.92400  2.44100   1.000 65.13011  ?  202 SER A HG     1 
ATOM   571  N  N      . SER A 1 39 ? 36.10000  20.98000  2.75800   1.000 45.32858  ?  203 SER A N      1 
ATOM   572  C  CA     . SER A 1 39 ? 35.38200  21.26100  1.52300   1.000 51.11381  ?  203 SER A CA     1 
ATOM   573  C  C      . SER A 1 39 ? 36.21600  20.88000  0.30900   1.000 51.74531  ?  203 SER A C      1 
ATOM   574  O  O      . SER A 1 39 ? 35.72900  20.19200  -0.58800  1.000 48.98176  ?  203 SER A O      1 
ATOM   575  C  CB     . SER A 1 39 ? 34.97700  22.72700  1.44000   1.000 48.87176  ?  203 SER A CB     1 
ATOM   576  O  OG     . SER A 1 39 ? 34.07000  22.86700  0.36800   1.000 60.11057  ?  203 SER A OG     1 
ATOM   577  H  H      . SER A 1 39 ? 36.24600  21.66200  3.26100   1.000 54.39430  ?  203 SER A H      1 
ATOM   578  H  HA     . SER A 1 39 ? 34.57200  20.72800  1.50500   1.000 61.33657  ?  203 SER A HA     1 
ATOM   579  H  HB2    . SER A 1 39 ? 34.54600  22.99200  2.26700   1.000 58.64611  ?  203 SER A HB2    1 
ATOM   580  H  HB3    . SER A 1 39 ? 35.76200  23.27200  1.27500   1.000 58.64611  ?  203 SER A HB3    1 
ATOM   581  H  HG     . SER A 1 39 ? 33.39200  22.38900  0.50100   1.000 72.13269  ?  203 SER A HG     1 
ATOM   582  N  N      . LYS A 1 40 ? 37.49700  21.23200  0.32100   0.594 52.59784  ?  204 LYS A N      1 
ATOM   583  C  CA     . LYS A 1 40 ? 38.34500  21.07500  -0.85500  1.000 51.50875  ?  204 LYS A CA     1 
ATOM   584  C  C      . LYS A 1 40 ? 38.94200  19.68200  -1.00300  1.000 51.88879  ?  204 LYS A C      1 
ATOM   585  O  O      . LYS A 1 40 ? 39.24300  19.29500  -2.12500  1.000 60.11837  ?  204 LYS A O      1 
ATOM   586  C  CB     . LYS A 1 40 ? 39.48200  22.11000  -0.82000  1.000 59.42276  ?  204 LYS A CB     1 
ATOM   587  C  CG     . LYS A 1 40 ? 38.97900  23.56200  -0.95100  1.000 64.08279  ?  204 LYS A CG     1 
ATOM   588  C  CD     . LYS A 1 40 ? 40.11000  24.60500  -0.93600  1.000 70.02293  ?  204 LYS A CD     1 
ATOM   589  C  CE     . LYS A 1 40 ? 40.64600  24.86200  0.48200   0.000 64.96773  ?  204 LYS A CE     1 
ATOM   590  N  NZ     . LYS A 1 40 ? 41.97500  24.23100  0.79400   1.000 68.26126  ?  204 LYS A NZ     1 
ATOM   591  H  H      . LYS A 1 40 ? 37.90200  21.56600  1.00200   0.530 63.11740  ?  204 LYS A H      1 
ATOM   592  H  HA     . LYS A 1 40 ? 37.81200  21.25100  -1.64600  1.000 61.81050  ?  204 LYS A HA     1 
ATOM   593  H  HB2    . LYS A 1 40 ? 39.95400  22.03200  0.02400   1.000 71.30731  ?  204 LYS A HB2    1 
ATOM   594  H  HB3    . LYS A 1 40 ? 40.08900  21.93600  -1.55600  1.000 71.30731  ?  204 LYS A HB3    1 
ATOM   595  H  HG2    . LYS A 1 40 ? 38.50300  23.65300  -1.79100  1.000 76.89935  ?  204 LYS A HG2    1 
ATOM   596  H  HG3    . LYS A 1 40 ? 38.38100  23.75600  -0.21200  1.000 76.89935  ?  204 LYS A HG3    1 
ATOM   597  H  HD2    . LYS A 1 40 ? 40.84500  24.28500  -1.48300  1.000 84.02751  ?  204 LYS A HD2    1 
ATOM   598  H  HD3    . LYS A 1 40 ? 39.77300  25.44400  -1.28800  1.000 84.02751  ?  204 LYS A HD3    1 
ATOM   599  H  HE2    . LYS A 1 40 ? 40.74400  25.81900  0.60400   0.000 77.96128  ?  204 LYS A HE2    1 
ATOM   600  H  HE3    . LYS A 1 40 ? 40.00400  24.51900  1.12300   0.000 77.96128  ?  204 LYS A HE3    1 
ATOM   601  H  HZ1    . LYS A 1 40 ? 42.21500  24.42500  1.62900   1.000 81.91351  ?  204 LYS A HZ1    1 
ATOM   602  H  HZ2    . LYS A 1 40 ? 41.92000  23.34700  0.70700   1.000 81.91351  ?  204 LYS A HZ2    1 
ATOM   603  H  HZ3    . LYS A 1 40 ? 42.59600  24.53800  0.23500   1.000 81.91351  ?  204 LYS A HZ3    1 
ATOM   604  N  N      . HIS A 1 41 ? 39.19400  18.95600  0.09400   1.000 51.16312  ?  205 HIS A N      1 
ATOM   605  C  CA     . HIS A 1 41 ? 39.98600  17.69300  0.06400   1.000 53.60787  ?  205 HIS A CA     1 
ATOM   606  C  C      . HIS A 1 41 ? 39.16900  16.44400  0.39800   1.000 49.82514  ?  205 HIS A C      1 
ATOM   607  O  O      . HIS A 1 41 ? 39.77100  15.35300  0.44800   1.000 45.47333  ?  205 HIS A O      1 
ATOM   608  C  CB     . HIS A 1 41 ? 41.12300  17.79200  1.08600   1.000 67.39430  ?  205 HIS A CB     1 
ATOM   609  C  CG     . HIS A 1 41 ? 42.39700  17.12800  0.68400   1.000 92.80151  ?  205 HIS A CG     1 
ATOM   610  N  ND1    . HIS A 1 41 ? 42.46300  15.91400  0.03700   1.000 102.17743 ?  205 HIS A ND1    1 
ATOM   611  C  CD2    . HIS A 1 41 ? 43.66200  17.52300  0.85400   1.000 107.97339 ?  205 HIS A CD2    1 
ATOM   612  C  CE1    . HIS A 1 41 ? 43.73100  15.59700  -0.17000  1.000 100.71573 ?  205 HIS A CE1    1 
ATOM   613  N  NE2    . HIS A 1 41 ? 44.47700  16.56200  0.31700   1.000 111.00221 ?  205 HIS A NE2    1 
ATOM   614  H  H      . HIS A 1 41 ? 38.91800  19.16800  0.88000   1.000 61.39574  ?  205 HIS A H      1 
ATOM   615  H  HA     . HIS A 1 41 ? 40.37600  17.57600  -0.81600  1.000 64.32944  ?  205 HIS A HA     1 
ATOM   616  H  HB2    . HIS A 1 41 ? 41.31800  18.73000  1.24000   1.000 80.87316  ?  205 HIS A HB2    1 
ATOM   617  H  HB3    . HIS A 1 41 ? 40.82900  17.38200  1.91200   1.000 80.87316  ?  205 HIS A HB3    1 
ATOM   618  H  HD1    . HIS A 1 41 ? 41.78600  15.43600  -0.19300  1.000 122.61291 ?  205 HIS A HD1    1 
ATOM   619  H  HD2    . HIS A 1 41 ? 43.94000  18.31000  1.26400   1.000 129.56806 ?  205 HIS A HD2    1 
ATOM   620  H  HE1    . HIS A 1 41 ? 44.04000  14.82800  -0.59200  1.000 120.85888 ?  205 HIS A HE1    1 
ATOM   621  N  N      . LYS A 1 42 ? 37.86200  16.55300  0.61700   1.000 43.72282  ?  206 LYS A N      1 
ATOM   622  C  CA     . LYS A 1 42 ? 37.10400  15.37600  1.00800   1.000 44.02069  ?  206 LYS A CA     1 
ATOM   623  C  C      . LYS A 1 42 ? 37.12300  14.29800  -0.06500  1.000 40.89107  ?  206 LYS A C      1 
ATOM   624  O  O      . LYS A 1 42 ? 37.01800  13.11900  0.28300   1.000 37.07890  ?  206 LYS A O      1 
ATOM   625  C  CB     . LYS A 1 42 ? 35.66000  15.75500  1.33900   1.000 45.14373  ?  206 LYS A CB     1 
ATOM   626  C  CG     . LYS A 1 42 ? 34.93700  16.60100  0.30300   1.000 40.32988  ?  206 LYS A CG     1 
ATOM   627  C  CD     . LYS A 1 42 ? 33.61400  17.16000  0.90800   1.000 43.24257  ?  206 LYS A CD     1 
ATOM   628  C  CE     . LYS A 1 42 ? 32.63200  17.50000  -0.19400  1.000 45.41896  ?  206 LYS A CE     1 
ATOM   629  N  NZ     . LYS A 1 42 ? 32.97100  18.76100  -0.90600  1.000 55.91244  ?  206 LYS A NZ     1 
ATOM   630  H  H      . LYS A 1 42 ? 37.40800  17.27900  0.55300   1.000 52.46738  ?  206 LYS A H      1 
ATOM   631  H  HA     . LYS A 1 42 ? 37.50200  15.00200  1.80900   1.000 52.82483  ?  206 LYS A HA     1 
ATOM   632  H  HB2    . LYS A 1 42 ? 35.14900  14.93800  1.45300   1.000 54.17247  ?  206 LYS A HB2    1 
ATOM   633  H  HB3    . LYS A 1 42 ? 35.65900  16.25400  2.17100   1.000 54.17247  ?  206 LYS A HB3    1 
ATOM   634  H  HG2    . LYS A 1 42 ? 35.49000  17.35100  0.03900   1.000 48.39586  ?  206 LYS A HG2    1 
ATOM   635  H  HG3    . LYS A 1 42 ? 34.71900  16.05200  -0.46700  1.000 48.39586  ?  206 LYS A HG3    1 
ATOM   636  H  HD2    . LYS A 1 42 ? 33.21200  16.49000  1.48200   1.000 51.89108  ?  206 LYS A HD2    1 
ATOM   637  H  HD3    . LYS A 1 42 ? 33.80400  17.96800  1.41000   1.000 51.89108  ?  206 LYS A HD3    1 
ATOM   638  H  HE2    . LYS A 1 42 ? 32.62300  16.78100  -0.84500  1.000 54.50275  ?  206 LYS A HE2    1 
ATOM   639  H  HE3    . LYS A 1 42 ? 31.74900  17.60500  0.19400   1.000 54.50275  ?  206 LYS A HE3    1 
ATOM   640  H  HZ1    . LYS A 1 42 ? 32.37000  18.92200  -1.54300  1.000 67.09493  ?  206 LYS A HZ1    1 
ATOM   641  H  HZ2    . LYS A 1 42 ? 32.97400  19.44200  -0.33300  1.000 67.09493  ?  206 LYS A HZ2    1 
ATOM   642  H  HZ3    . LYS A 1 42 ? 33.77600  18.69200  -1.27900  1.000 67.09493  ?  206 LYS A HZ3    1 
ATOM   643  N  N      . GLU A 1 43 ? 37.26300  14.66100  -1.36000  1.000 38.67570  ?  207 GLU A N      1 
ATOM   644  C  CA     . GLU A 1 43 ? 37.19700  13.63200  -2.39900  1.000 41.17771  ?  207 GLU A CA     1 
ATOM   645  C  C      . GLU A 1 43 ? 38.39300  12.67300  -2.34700  1.000 39.29167  ?  207 GLU A C      1 
ATOM   646  O  O      . GLU A 1 43 ? 38.23700  11.50300  -2.67500  1.000 39.64565  ?  207 GLU A O      1 
ATOM   647  C  CB     . GLU A 1 43 ? 37.04400  14.27100  -3.78900  1.000 39.35140  ?  207 GLU A CB     1 
ATOM   648  C  CG     . GLU A 1 43 ? 35.84800  15.18100  -3.91100  1.000 43.20914  ?  207 GLU A CG     1 
ATOM   649  C  CD     . GLU A 1 43 ? 34.46800  14.47000  -3.81500  1.000 48.90934  ?  207 GLU A CD     1 
ATOM   650  O  OE1    . GLU A 1 43 ? 34.42000  13.22000  -3.80200  1.000 45.10027  ?  207 GLU A OE1    1 
ATOM   651  O  OE2    . GLU A 1 43 ? 33.42500  15.17500  -3.76100  1.000 46.42645  -1 207 GLU A OE2    1 
ATOM   652  H  H      . GLU A 1 43 ? 37.39100  15.46200  -1.64400  1.000 46.41084  ?  207 GLU A H      1 
ATOM   653  H  HA     . GLU A 1 43 ? 36.40100  13.10000  -2.24200  1.000 49.41326  ?  207 GLU A HA     1 
ATOM   654  H  HB2    . GLU A 1 43 ? 37.83700  14.79600  -3.98100  1.000 47.22168  ?  207 GLU A HB2    1 
ATOM   655  H  HB3    . GLU A 1 43 ? 36.94900  13.56600  -4.44900  1.000 47.22168  ?  207 GLU A HB3    1 
ATOM   656  H  HG2    . GLU A 1 43 ? 35.88200  15.84000  -3.20200  1.000 51.85097  ?  207 GLU A HG2    1 
ATOM   657  H  HG3    . GLU A 1 43 ? 35.88700  15.62700  -4.77100  1.000 51.85097  ?  207 GLU A HG3    1 
ATOM   658  N  N      . ALA A 1 44 ? 39.57400  13.10600  -1.90700  1.000 40.23860  ?  208 ALA A N      1 
ATOM   659  C  CA     . ALA A 1 44 ? 40.68500  12.15900  -1.79000  1.000 36.83752  ?  208 ALA A CA     1 
ATOM   660  C  C      . ALA A 1 44 ? 40.34600  11.08900  -0.76900  1.000 38.37648  ?  208 ALA A C      1 
ATOM   661  O  O      . ALA A 1 44 ? 40.67800  9.89500   -0.93700  1.000 38.88084  ?  208 ALA A O      1 
ATOM   662  C  CB     . ALA A 1 44 ? 41.94900  12.90500  -1.39900  1.000 44.96086  ?  208 ALA A CB     1 
ATOM   663  H  H      . ALA A 1 44 ? 39.75600  13.91400  -1.67700  1.000 48.28632  ?  208 ALA A H      1 
ATOM   664  H  HA     . ALA A 1 44 ? 40.83500  11.72900  -2.64700  1.000 44.20502  ?  208 ALA A HA     1 
ATOM   665  H  HB1    . ALA A 1 44 ? 42.68200  12.27300  -1.33900  1.000 53.95304  ?  208 ALA A HB1    1 
ATOM   666  H  HB2    . ALA A 1 44 ? 42.14200  13.57400  -2.07500  1.000 53.95304  ?  208 ALA A HB2    1 
ATOM   667  H  HB3    . ALA A 1 44 ? 41.80900  13.33300  -0.54000  1.000 53.95304  ?  208 ALA A HB3    1 
ATOM   668  N  N      . LEU A 1 45 ? 39.62800  11.48200  0.26100   1.000 41.30988  ?  209 LEU A N      1 
ATOM   669  C  CA     . LEU A 1 45 ? 39.27900  10.52500  1.30500   1.000 38.36555  ?  209 LEU A CA     1 
ATOM   670  C  C      . LEU A 1 45 ? 38.15400  9.59400   0.81900   1.000 35.77927  ?  209 LEU A C      1 
ATOM   671  O  O      . LEU A 1 45 ? 38.24200  8.36400   0.98900   1.000 31.15679  ?  209 LEU A O      1 
ATOM   672  C  CB     . LEU A 1 45 ? 38.92800  11.30200  2.57600   1.000 43.03966  ?  209 LEU A CB     1 
ATOM   673  C  CG     . LEU A 1 45 ? 38.61500  10.48500  3.84100   1.000 38.17338  ?  209 LEU A CG     1 
ATOM   674  C  CD1    . LEU A 1 45 ? 38.68800  11.37700  5.10400   1.000 42.39964  ?  209 LEU A CD1    1 
ATOM   675  C  CD2    . LEU A 1 45 ? 37.26000  9.82600   3.69700   1.000 41.35404  ?  209 LEU A CD2    1 
ATOM   676  H  H      . LEU A 1 45 ? 39.33200  12.28000  0.38600   1.000 49.57186  ?  209 LEU A H      1 
ATOM   677  H  HA     . LEU A 1 45 ? 40.05500  9.97600   1.49900   1.000 46.03866  ?  209 LEU A HA     1 
ATOM   678  H  HB2    . LEU A 1 45 ? 39.67800  11.87800  2.79100   1.000 51.64759  ?  209 LEU A HB2    1 
ATOM   679  H  HB3    . LEU A 1 45 ? 38.15200  11.85300  2.38800   1.000 51.64759  ?  209 LEU A HB3    1 
ATOM   680  H  HG     . LEU A 1 45 ? 39.27900  9.78400   3.93300   1.000 45.80805  ?  209 LEU A HG     1 
ATOM   681  H  HD11   . LEU A 1 45 ? 38.49300  10.83500  5.88500   1.000 50.87957  ?  209 LEU A HD11   1 
ATOM   682  H  HD12   . LEU A 1 45 ? 39.58000  11.75100  5.17500   1.000 50.87957  ?  209 LEU A HD12   1 
ATOM   683  H  HD13   . LEU A 1 45 ? 38.03500  12.09000  5.02500   1.000 50.87957  ?  209 LEU A HD13   1 
ATOM   684  H  HD21   . LEU A 1 45 ? 36.85600  9.74500   4.57500   1.000 49.62485  ?  209 LEU A HD21   1 
ATOM   685  H  HD22   . LEU A 1 45 ? 36.69800  10.37100  3.12500   1.000 49.62485  ?  209 LEU A HD22   1 
ATOM   686  H  HD23   . LEU A 1 45 ? 37.37600  8.94600   3.30600   1.000 49.62485  ?  209 LEU A HD23   1 
ATOM   687  N  N      . ALA A 1 46 ? 37.11300  10.16100  0.18700   1.000 34.33245  ?  210 ALA A N      1 
ATOM   688  C  CA     . ALA A 1 46 ? 36.10300  9.33100   -0.45900  1.000 32.94200  ?  210 ALA A CA     1 
ATOM   689  C  C      . ALA A 1 46 ? 36.74700  8.30300   -1.38300  1.000 36.04299  ?  210 ALA A C      1 
ATOM   690  O  O      . ALA A 1 46 ? 36.45000  7.09800   -1.33300  1.000 32.41065  ?  210 ALA A O      1 
ATOM   691  C  CB     . ALA A 1 46 ? 35.11700  10.19800  -1.25200  1.000 32.59439  ?  210 ALA A CB     1 
ATOM   692  H  H      . ALA A 1 46 ? 36.97700  11.00800  0.12300   1.000 41.19894  ?  210 ALA A H      1 
ATOM   693  H  HA     . ALA A 1 46 ? 35.60400  8.85300   0.22100   1.000 39.53040  ?  210 ALA A HA     1 
ATOM   694  H  HB1    . ALA A 1 46 ? 34.48900  9.61400   -1.70200  1.000 39.11327  ?  210 ALA A HB1    1 
ATOM   695  H  HB2    . ALA A 1 46 ? 34.64700  10.78600  -0.64000  1.000 39.11327  ?  210 ALA A HB2    1 
ATOM   696  H  HB3    . ALA A 1 46 ? 35.60900  10.72100  -1.90400  1.000 39.11327  ?  210 ALA A HB3    1 
ATOM   697  N  N      . HIS A 1 47 ? 37.66000  8.77300   -2.23000  1.000 40.04645  ?  211 HIS A N      1 
ATOM   698  C  CA     . HIS A 1 47 ? 38.31000  7.87800   -3.16200  1.000 39.91661  ?  211 HIS A CA     1 
ATOM   699  C  C      . HIS A 1 47 ? 39.03800  6.76500   -2.44300  1.000 39.62319  ?  211 HIS A C      1 
ATOM   700  O  O      . HIS A 1 47 ? 38.96200  5.59500   -2.84700  1.000 38.49223  ?  211 HIS A O      1 
ATOM   701  C  CB     . HIS A 1 47 ? 39.29400  8.65000   -4.01300  1.000 41.88636  ?  211 HIS A CB     1 
ATOM   702  C  CG     . HIS A 1 47 ? 39.71300  7.90700   -5.23100  1.000 50.15158  ?  211 HIS A CG     1 
ATOM   703  N  ND1    . HIS A 1 47 ? 38.99300  6.85900   -5.76400  1.000 59.77343  ?  211 HIS A ND1    1 
ATOM   704  C  CD2    . HIS A 1 47 ? 40.79800  8.05600   -6.01400  1.000 56.64049  ?  211 HIS A CD2    1 
ATOM   705  C  CE1    . HIS A 1 47 ? 39.60800  6.41700   -6.85000  1.000 66.49411  ?  211 HIS A CE1    1 
ATOM   706  N  NE2    . HIS A 1 47 ? 40.70500  7.13000   -7.02500  1.000 62.73080  ?  211 HIS A NE2    1 
ATOM   707  H  H      . HIS A 1 47 ? 37.91300  9.59300   -2.28000  1.000 48.05574  ?  211 HIS A H      1 
ATOM   708  H  HA     . HIS A 1 47 ? 37.64100  7.48300   -3.74200  1.000 47.89993  ?  211 HIS A HA     1 
ATOM   709  H  HB2    . HIS A 1 47 ? 38.88200  9.48100   -4.29600  1.000 50.26364  ?  211 HIS A HB2    1 
ATOM   710  H  HB3    . HIS A 1 47 ? 40.08800  8.83600   -3.48800  1.000 50.26364  ?  211 HIS A HB3    1 
ATOM   711  H  HD2    . HIS A 1 47 ? 41.47000  8.69100   -5.90900  1.000 67.96859  ?  211 HIS A HD2    1 
ATOM   712  H  HE1    . HIS A 1 47 ? 39.32300  5.71500   -7.39000  1.000 79.79293  ?  211 HIS A HE1    1 
ATOM   713  H  HE2    . HIS A 1 47 ? 41.27900  7.01800   -7.65600  1.000 75.27696  ?  211 HIS A HE2    1 
ATOM   714  N  N      . ARG A 1 48 ? 39.75700  7.11100   -1.37600  1.000 40.85002  ?  212 ARG A N      1 
ATOM   715  C  CA     . ARG A 1 48 ? 40.46600  6.08200   -0.62400  1.000 39.41047  ?  212 ARG A CA     1 
ATOM   716  C  C      . ARG A 1 48 ? 39.50600  5.05400   -0.02600  1.000 36.64454  ?  212 ARG A C      1 
ATOM   717  O  O      . ARG A 1 48 ? 39.80500  3.85100   -0.00700  1.000 38.64157  ?  212 ARG A O      1 
ATOM   718  C  CB     . ARG A 1 48 ? 41.33300  6.72200   0.46000   1.000 37.59300  ?  212 ARG A CB     1 
ATOM   719  C  CG     . ARG A 1 48 ? 41.86500  5.69700   1.35800   1.000 35.82709  ?  212 ARG A CG     1 
ATOM   720  C  CD     . ARG A 1 48 ? 42.90900  6.28400   2.26000   1.000 44.19768  ?  212 ARG A CD     1 
ATOM   721  N  NE     . ARG A 1 48 ? 43.38500  5.34600   3.26000   1.000 41.31388  ?  212 ARG A NE     1 
ATOM   722  C  CZ     . ARG A 1 48 ? 44.28700  5.65100   4.18500   1.000 44.31134  ?  212 ARG A CZ     1 
ATOM   723  N  NH1    . ARG A 1 48 ? 44.81900  6.86500   4.27200   1.000 38.66414  ?  212 ARG A NH1    1 
ATOM   724  N  NH2    . ARG A 1 48 ? 44.66500  4.71600   5.04800   1.000 48.04865  ?  212 ARG A NH2    1 
ATOM   725  H  H      . ARG A 1 48 ? 39.84800  7.91100   -1.07500  1.000 49.02002  ?  212 ARG A H      1 
ATOM   726  H  HA     . ARG A 1 48 ? 41.05800  5.61000   -1.23100  1.000 47.29256  ?  212 ARG A HA     1 
ATOM   727  H  HB2    . ARG A 1 48 ? 42.07800  7.18600   0.04700   1.000 45.11159  ?  212 ARG A HB2    1 
ATOM   728  H  HB3    . ARG A 1 48 ? 40.79600  7.33900   0.98100   1.000 45.11159  ?  212 ARG A HB3    1 
ATOM   729  H  HG2    . ARG A 1 48 ? 41.15600  5.34800   1.92000   1.000 42.99250  ?  212 ARG A HG2    1 
ATOM   730  H  HG3    . ARG A 1 48 ? 42.27000  4.98500   0.83800   1.000 42.99250  ?  212 ARG A HG3    1 
ATOM   731  H  HD2    . ARG A 1 48 ? 43.66900  6.56200   1.72400   1.000 53.03722  ?  212 ARG A HD2    1 
ATOM   732  H  HD3    . ARG A 1 48 ? 42.53200  7.04900   2.72200   1.000 53.03722  ?  212 ARG A HD3    1 
ATOM   733  H  HE     . ARG A 1 48 ? 42.98500  4.58700   3.32300   1.000 49.57666  ?  212 ARG A HE     1 
ATOM   734  H  HH11   . ARG A 1 48 ? 44.58400  7.48100   3.72000   1.000 46.39696  ?  212 ARG A HH11   1 
ATOM   735  H  HH12   . ARG A 1 48 ? 45.40100  7.03500   4.88200   1.000 46.39696  ?  212 ARG A HH12   1 
ATOM   736  H  HH21   . ARG A 1 48 ? 44.32700  3.92700   5.00200   1.000 57.65839  ?  212 ARG A HH21   1 
ATOM   737  H  HH22   . ARG A 1 48 ? 45.24800  4.90000   5.65300   1.000 57.65839  ?  212 ARG A HH22   1 
ATOM   738  N  N      . TRP A 1 49 ? 38.34400  5.49800   0.45600   1.000 39.13378  ?  213 TRP A N      1 
ATOM   739  C  CA     . TRP A 1 49 ? 37.37100  4.54100   0.99300   1.000 34.84535  ?  213 TRP A CA     1 
ATOM   740  C  C      . TRP A 1 49 ? 36.93700  3.55400   -0.08800  1.000 37.72374  ?  213 TRP A C      1 
ATOM   741  O  O      . TRP A 1 49 ? 36.82700  2.33800   0.15800   1.000 42.97394  ?  213 TRP A O      1 
ATOM   742  C  CB     . TRP A 1 49 ? 36.16300  5.30200   1.55800   1.000 36.00333  ?  213 TRP A CB     1 
ATOM   743  C  CG     . TRP A 1 49 ? 34.94000  4.47600   1.84700   1.000 35.64562  ?  213 TRP A CG     1 
ATOM   744  C  CD1    . TRP A 1 49 ? 33.66600  4.67300   1.35300   1.000 39.15203  ?  213 TRP A CD1    1 
ATOM   745  C  CD2    . TRP A 1 49 ? 34.85600  3.36400   2.73700   1.000 36.95452  ?  213 TRP A CD2    1 
ATOM   746  N  NE1    . TRP A 1 49 ? 32.82200  3.72700   1.85600   1.000 37.79935  ?  213 TRP A NE1    1 
ATOM   747  C  CE2    . TRP A 1 49 ? 33.52200  2.89800   2.69400   1.000 35.82016  ?  213 TRP A CE2    1 
ATOM   748  C  CE3    . TRP A 1 49 ? 35.78300  2.70500   3.54500   1.000 37.97126  ?  213 TRP A CE3    1 
ATOM   749  C  CZ2    . TRP A 1 49 ? 33.09300  1.80000   3.42900   1.000 37.37983  ?  213 TRP A CZ2    1 
ATOM   750  C  CZ3    . TRP A 1 49 ? 35.37900  1.61900   4.25800   1.000 37.77277  ?  213 TRP A CZ3    1 
ATOM   751  C  CH2    . TRP A 1 49 ? 34.03400  1.17500   4.22600   1.000 37.30939  ?  213 TRP A CH2    1 
ATOM   752  H  H      . TRP A 1 49 ? 38.09900  6.32200   0.48400   1.000 46.96053  ?  213 TRP A H      1 
ATOM   753  H  HA     . TRP A 1 49 ? 37.78000  4.04000   1.71600   1.000 41.81442  ?  213 TRP A HA     1 
ATOM   754  H  HB2    . TRP A 1 49 ? 36.43200  5.71900   2.39000   1.000 43.20400  ?  213 TRP A HB2    1 
ATOM   755  H  HB3    . TRP A 1 49 ? 35.90700  5.98700   0.92100   1.000 43.20400  ?  213 TRP A HB3    1 
ATOM   756  H  HD1    . TRP A 1 49 ? 33.42500  5.33600   0.74700   1.000 46.98244  ?  213 TRP A HD1    1 
ATOM   757  H  HE1    . TRP A 1 49 ? 31.98800  3.65000   1.66200   1.000 45.35922  ?  213 TRP A HE1    1 
ATOM   758  H  HE3    . TRP A 1 49 ? 36.67200  2.97900   3.56400   1.000 45.56551  ?  213 TRP A HE3    1 
ATOM   759  H  HZ2    . TRP A 1 49 ? 32.20700  1.51800   3.41100   1.000 44.85580  ?  213 TRP A HZ2    1 
ATOM   760  H  HZ3    . TRP A 1 49 ? 35.99300  1.17300   4.79600   1.000 45.32733  ?  213 TRP A HZ3    1 
ATOM   761  H  HH2    . TRP A 1 49 ? 33.78500  0.43600   4.73200   1.000 44.77127  ?  213 TRP A HH2    1 
ATOM   762  N  N      . GLY A 1 50 ? 36.69800  4.06300   -1.30300  1.000 40.80509  ?  214 GLY A N      1 
ATOM   763  C  CA     . GLY A 1 50 ? 36.21000  3.19700   -2.36900  1.000 42.19526  ?  214 GLY A CA     1 
ATOM   764  C  C      . GLY A 1 50 ? 37.27600  2.23300   -2.86100  1.000 43.84444  ?  214 GLY A C      1 
ATOM   765  O  O      . GLY A 1 50 ? 36.99400  1.06200   -3.16800  1.000 45.29568  ?  214 GLY A O      1 
ATOM   766  H  H      . GLY A 1 50 ? 36.80900  4.88600   -1.52700  1.000 48.96611  ?  214 GLY A H      1 
ATOM   767  H  HA2    . GLY A 1 50 ? 35.45300  2.68200   -2.04800  1.000 50.63431  ?  214 GLY A HA2    1 
ATOM   768  H  HA3    . GLY A 1 50 ? 35.91900  3.73900   -3.11900  1.000 50.63431  ?  214 GLY A HA3    1 
ATOM   769  N  N      . ILE A 1 51 ? 38.51800  2.70300   -2.94400  1.000 45.62812  ?  215 ILE A N      1 
ATOM   770  C  CA     . ILE A 1 51 ? 39.61000  1.79300   -3.26700  1.000 44.17995  ?  215 ILE A CA     1 
ATOM   771  C  C      . ILE A 1 51 ? 39.65900  0.68200   -2.23300  1.000 48.00043  ?  215 ILE A C      1 
ATOM   772  O  O      . ILE A 1 51 ? 39.72800  -0.50900  -2.56700  1.000 50.20831  ?  215 ILE A O      1 
ATOM   773  C  CB     . ILE A 1 51 ? 40.94400  2.55800   -3.34000  1.000 47.51677  ?  215 ILE A CB     1 
ATOM   774  C  CG1    . ILE A 1 51 ? 40.90800  3.60800   -4.46800  1.000 50.74483  ?  215 ILE A CG1    1 
ATOM   775  C  CG2    . ILE A 1 51 ? 42.09600  1.59600   -3.56600  1.000 50.26886  ?  215 ILE A CG2    1 
ATOM   776  C  CD1    . ILE A 1 51 ? 42.05600  4.65600   -4.34600  1.000 51.65773  ?  215 ILE A CD1    1 
ATOM   777  H  H      . ILE A 1 51 ? 38.75000  3.52200   -2.82100  1.000 54.75374  ?  215 ILE A H      1 
ATOM   778  H  HA     . ILE A 1 51 ? 39.44400  1.39200   -4.13400  1.000 53.01594  ?  215 ILE A HA     1 
ATOM   779  H  HB     . ILE A 1 51 ? 41.08400  3.01600   -2.49600  1.000 57.02012  ?  215 ILE A HB     1 
ATOM   780  H  HG12   . ILE A 1 51 ? 41.00400  3.15700   -5.32200  1.000 60.89379  ?  215 ILE A HG12   1 
ATOM   781  H  HG13   . ILE A 1 51 ? 40.06400  4.08400   -4.43700  1.000 60.89379  ?  215 ILE A HG13   1 
ATOM   782  H  HG21   . ILE A 1 51 ? 42.88900  2.10000   -3.80500  1.000 60.32263  ?  215 ILE A HG21   1 
ATOM   783  H  HG22   . ILE A 1 51 ? 42.25900  1.09700   -2.75100  1.000 60.32263  ?  215 ILE A HG22   1 
ATOM   784  H  HG23   . ILE A 1 51 ? 41.86300  0.98900   -4.28600  1.000 60.32263  ?  215 ILE A HG23   1 
ATOM   785  H  HD11   . ILE A 1 51 ? 41.90600  5.36300   -4.99300  1.000 61.98927  ?  215 ILE A HD11   1 
ATOM   786  H  HD12   . ILE A 1 51 ? 42.05300  5.02300   -3.44800  1.000 61.98927  ?  215 ILE A HD12   1 
ATOM   787  H  HD13   . ILE A 1 51 ? 42.90400  4.22000   -4.52300  1.000 61.98927  ?  215 ILE A HD13   1 
ATOM   788  N  N      . GLN A 1 52 ? 39.57500  1.05100   -0.95200  1.000 45.08547  ?  216 GLN A N      1 
ATOM   789  C  CA     . GLN A 1 52 ? 39.76500  0.04600   0.08500   1.000 42.10582  ?  216 GLN A CA     1 
ATOM   790  C  C      . GLN A 1 52 ? 38.63100  -0.97200  0.10500   1.000 45.09864  ?  216 GLN A C      1 
ATOM   791  O  O      . GLN A 1 52 ? 38.86300  -2.12700  0.47800   0.856 47.62724  ?  216 GLN A O      1 
ATOM   792  C  CB     . GLN A 1 52 ? 39.93700  0.73400   1.42700   1.000 42.37883  ?  216 GLN A CB     1 
ATOM   793  C  CG     . GLN A 1 52 ? 39.99000  -0.26800  2.57600   1.000 51.01640  ?  216 GLN A CG     1 
ATOM   794  C  CD     . GLN A 1 52 ? 40.50300  0.28500   3.91800   1.000 51.52690  ?  216 GLN A CD     1 
ATOM   795  O  OE1    . GLN A 1 52 ? 40.19600  -0.29400  4.95500   1.000 55.76846  ?  216 GLN A OE1    1 
ATOM   796  N  NE2    . GLN A 1 52 ? 41.30900  1.34900   3.89900   1.000 53.77140  ?  216 GLN A NE2    1 
ATOM   797  H  H      . GLN A 1 52 ? 39.41500  1.84700   -0.66900  1.000 54.10256  ?  216 GLN A H      1 
ATOM   798  H  HA     . GLN A 1 52 ? 40.58500  -0.43700  -0.10200  1.000 50.52699  ?  216 GLN A HA     1 
ATOM   799  H  HB2    . GLN A 1 52 ? 40.76700  1.23400   1.41100   1.000 50.85459  ?  216 GLN A HB2    1 
ATOM   800  H  HB3    . GLN A 1 52 ? 39.18800  1.33100   1.57900   1.000 50.85459  ?  216 GLN A HB3    1 
ATOM   801  H  HG2    . GLN A 1 52 ? 39.09500  -0.60800  2.73000   1.000 61.21968  ?  216 GLN A HG2    1 
ATOM   802  H  HG3    . GLN A 1 52 ? 40.57400  -0.99900  2.32000   1.000 61.21968  ?  216 GLN A HG3    1 
ATOM   803  H  HE21   . GLN A 1 52 ? 41.51400  1.72800   3.15700   1.000 64.52568  ?  216 GLN A HE21   1 
ATOM   804  H  HE22   . GLN A 1 52 ? 41.61000  1.66900   4.63800   1.000 64.52568  ?  216 GLN A HE22   1 
ATOM   805  N  N      . LYS A 1 53 ? 37.40900  -0.58300  -0.31400  1.000 44.11270  ?  217 LYS A N      1 
ATOM   806  C  CA     . LYS A 1 53 ? 36.30000  -1.54300  -0.41700  1.000 40.92462  ?  217 LYS A CA     1 
ATOM   807  C  C      . LYS A 1 53 ? 36.26700  -2.32600  -1.73700  1.000 44.90322  ?  217 LYS A C      1 
ATOM   808  O  O      . LYS A 1 53 ? 35.48500  -3.27900  -1.86000  1.000 46.48765  ?  217 LYS A O      1 
ATOM   809  C  CB     . LYS A 1 53 ? 34.95800  -0.82100  -0.22500  1.000 41.71476  ?  217 LYS A CB     1 
ATOM   810  C  CG     . LYS A 1 53 ? 34.67400  -0.41500  1.24600   1.000 41.81165  ?  217 LYS A CG     1 
ATOM   811  C  CD     . LYS A 1 53 ? 34.13900  -1.57300  2.09200   1.000 40.49693  ?  217 LYS A CD     1 
ATOM   812  C  CE     . LYS A 1 53 ? 32.79400  -2.12500  1.63100   1.000 40.84961  ?  217 LYS A CE     1 
ATOM   813  N  NZ     . LYS A 1 53 ? 31.64800  -1.15900  1.62600   1.000 43.32248  ?  217 LYS A NZ     1 
ATOM   814  H  H      . LYS A 1 53 ? 37.20300  0.22100   -0.54000  1.000 52.93524  ?  217 LYS A H      1 
ATOM   815  H  HA     . LYS A 1 53 ? 36.38700  -2.18900  0.30100   1.000 49.10955  ?  217 LYS A HA     1 
ATOM   816  H  HB2    . LYS A 1 53 ? 34.96600  -0.00900  -0.75600  1.000 50.05772  ?  217 LYS A HB2    1 
ATOM   817  H  HB3    . LYS A 1 53 ? 34.24400  -1.40000  -0.53000  1.000 50.05772  ?  217 LYS A HB3    1 
ATOM   818  H  HG2    . LYS A 1 53 ? 35.49800  -0.10300  1.65200   1.000 50.17398  ?  217 LYS A HG2    1 
ATOM   819  H  HG3    . LYS A 1 53 ? 34.01100  0.29300   1.25400   1.000 50.17398  ?  217 LYS A HG3    1 
ATOM   820  H  HD2    . LYS A 1 53 ? 34.78000  -2.30000  2.06100   1.000 48.59631  ?  217 LYS A HD2    1 
ATOM   821  H  HD3    . LYS A 1 53 ? 34.03500  -1.27100  3.00700   1.000 48.59631  ?  217 LYS A HD3    1 
ATOM   822  H  HE2    . LYS A 1 53 ? 32.88800  -2.47100  0.73100   1.000 49.01953  ?  217 LYS A HE2    1 
ATOM   823  H  HE3    . LYS A 1 53 ? 32.54900  -2.85200  2.22500   1.000 49.01953  ?  217 LYS A HE3    1 
ATOM   824  H  HZ1    . LYS A 1 53 ? 30.91100  -1.56200  1.33200   1.000 51.98698  ?  217 LYS A HZ1    1 
ATOM   825  H  HZ2    . LYS A 1 53 ? 31.50300  -0.85500  2.45000   1.000 51.98698  ?  217 LYS A HZ2    1 
ATOM   826  H  HZ3    . LYS A 1 53 ? 31.83500  -0.47200  1.09200   1.000 51.98698  ?  217 LYS A HZ3    1 
ATOM   827  N  N      . GLY A 1 54 ? 37.08800  -1.97100  -2.71500  1.000 47.10767  ?  218 GLY A N      1 
ATOM   828  C  CA     . GLY A 1 54 ? 37.04700  -2.66200  -3.99300  1.000 44.39704  ?  218 GLY A CA     1 
ATOM   829  C  C      . GLY A 1 54 ? 35.82100  -2.36800  -4.83200  1.000 48.03753  ?  218 GLY A C      1 
ATOM   830  O  O      . GLY A 1 54 ? 35.43200  -3.18900  -5.67700  1.000 49.09567  ?  218 GLY A O      1 
ATOM   831  H  H      . GLY A 1 54 ? 37.67100  -1.34100  -2.66600  1.000 56.52921  ?  218 GLY A H      1 
ATOM   832  H  HA2    . GLY A 1 54 ? 37.83000  -2.41500  -4.51000  1.000 53.27645  ?  218 GLY A HA2    1 
ATOM   833  H  HA3    . GLY A 1 54 ? 37.08000  -3.61900  -3.83600  1.000 53.27645  ?  218 GLY A HA3    1 
ATOM   834  N  N      . ASN A 1 55 ? 35.21000  -1.21500  -4.64000  1.000 46.09180  ?  219 ASN A N      1 
ATOM   835  C  CA     . ASN A 1 55 ? 34.00400  -0.93400  -5.38700  1.000 44.49737  ?  219 ASN A CA     1 
ATOM   836  C  C      . ASN A 1 55 ? 34.28400  -0.75900  -6.87000  1.000 49.47588  ?  219 ASN A C      1 
ATOM   837  O  O      . ASN A 1 55 ? 35.35400  -0.29000  -7.29200  1.000 54.39093  ?  219 ASN A O      1 
ATOM   838  C  CB     . ASN A 1 55 ? 33.32400  0.31000   -4.85900  1.000 45.53230  ?  219 ASN A CB     1 
ATOM   839  C  CG     . ASN A 1 55 ? 32.89400  0.14000   -3.44900  1.000 42.14697  ?  219 ASN A CG     1 
ATOM   840  O  OD1    . ASN A 1 55 ? 32.54700  -0.96300  -3.03000  1.000 40.70479  ?  219 ASN A OD1    1 
ATOM   841  N  ND2    . ASN A 1 55 ? 32.93900  1.21100   -2.70300  1.000 34.85621  ?  219 ASN A ND2    1 
ATOM   842  H  H      . ASN A 1 55 ? 35.46300  -0.59500  -4.10000  1.000 55.31016  ?  219 ASN A H      1 
ATOM   843  H  HA     . ASN A 1 55 ? 33.39000  -1.67800  -5.28500  1.000 53.39684  ?  219 ASN A HA     1 
ATOM   844  H  HB2    . ASN A 1 55 ? 33.94500  1.05300   -4.89900  1.000 54.63876  ?  219 ASN A HB2    1 
ATOM   845  H  HB3    . ASN A 1 55 ? 32.53900  0.49900   -5.39600  1.000 54.63876  ?  219 ASN A HB3    1 
ATOM   846  H  HD21   . ASN A 1 55 ? 32.70300  1.17000   -1.87700  1.000 41.82745  ?  219 ASN A HD21   1 
ATOM   847  H  HD22   . ASN A 1 55 ? 33.19400  1.96000   -3.04100  1.000 41.82745  ?  219 ASN A HD22   1 
ATOM   848  N  N      . ARG A 1 56 ? 33.26600  -1.09200  -7.65500  1.000 44.17802  ?  220 ARG A N      1 
ATOM   849  C  CA     . ARG A 1 56 ? 33.36100  -1.03100  -9.10600  1.000 43.00425  ?  220 ARG A CA     1 
ATOM   850  C  C      . ARG A 1 56 ? 33.64800  0.37900   -9.57300  1.000 44.79536  ?  220 ARG A C      1 
ATOM   851  O  O      . ARG A 1 56 ? 34.56800  0.61200   -10.36100 1.000 48.79026  ?  220 ARG A O      1 
ATOM   852  C  CB     . ARG A 1 56 ? 32.04600  -1.53900  -9.69300  1.000 52.41808  ?  220 ARG A CB     1 
ATOM   853  C  CG     . ARG A 1 56 ? 31.96300  -1.54900  -11.18800 1.000 51.92114  ?  220 ARG A CG     1 
ATOM   854  C  CD     . ARG A 1 56 ? 30.53900  -1.96500  -11.59200 1.000 64.09461  ?  220 ARG A CD     1 
ATOM   855  N  NE     . ARG A 1 56 ? 29.78100  -0.87800  -12.21800 1.000 62.08580  ?  220 ARG A NE     1 
ATOM   856  C  CZ     . ARG A 1 56 ? 28.70600  -0.29500  -11.71000 0.000 53.21621  ?  220 ARG A CZ     1 
ATOM   857  N  NH1    . ARG A 1 56 ? 28.18800  -0.67200  -10.55300 0.000 49.76755  ?  220 ARG A NH1    1 
ATOM   858  N  NH2    . ARG A 1 56 ? 28.13200  0.68500   -12.38900 1.000 53.62182  ?  220 ARG A NH2    1 
ATOM   859  H  H      . ARG A 1 56 ? 32.50100  -1.35900  -7.36700  1.000 53.01363  ?  220 ARG A H      1 
ATOM   860  H  HA     . ARG A 1 56 ? 34.07900  -1.60900  -9.40900  1.000 51.60510  ?  220 ARG A HA     1 
ATOM   861  H  HB2    . ARG A 1 56 ? 31.90700  -2.44900  -9.38800  1.000 62.90170  ?  220 ARG A HB2    1 
ATOM   862  H  HB3    . ARG A 1 56 ? 31.32800  -0.97500  -9.36600  1.000 62.90170  ?  220 ARG A HB3    1 
ATOM   863  H  HG2    . ARG A 1 56 ? 32.13800  -0.66200  -11.53800 1.000 62.30537  ?  220 ARG A HG2    1 
ATOM   864  H  HG3    . ARG A 1 56 ? 32.59200  -2.19300  -11.54900 1.000 62.30537  ?  220 ARG A HG3    1 
ATOM   865  H  HD2    . ARG A 1 56 ? 30.59800  -2.69000  -12.23300 1.000 76.91353  ?  220 ARG A HD2    1 
ATOM   866  H  HD3    . ARG A 1 56 ? 30.06300  -2.26400  -10.80400 1.000 76.91353  ?  220 ARG A HD3    1 
ATOM   867  H  HE     . ARG A 1 56 ? 30.05800  -0.59400  -12.98100 1.000 74.50296  ?  220 ARG A HE     1 
ATOM   868  H  HH11   . ARG A 1 56 ? 28.54600  -1.30600  -10.09800 0.000 59.72106  ?  220 ARG A HH11   1 
ATOM   869  H  HH12   . ARG A 1 56 ? 27.48800  -0.27400  -10.25100 0.000 59.72106  ?  220 ARG A HH12   1 
ATOM   870  H  HH21   . ARG A 1 56 ? 28.46100  0.93500   -13.14300 1.000 64.34618  ?  220 ARG A HH21   1 
ATOM   871  H  HH22   . ARG A 1 56 ? 27.43200  1.07300   -12.07500 1.000 64.34618  ?  220 ARG A HH22   1 
ATOM   872  N  N      . LYS A 1 57 ? 32.85100  1.32600   -9.11500  1.000 46.84897  ?  221 LYS A N      1 
ATOM   873  C  CA     . LYS A 1 57 ? 32.95500  2.74200   -9.42000  1.000 43.11464  ?  221 LYS A CA     1 
ATOM   874  C  C      . LYS A 1 57 ? 33.85400  3.49700   -8.42100  1.000 43.35231  ?  221 LYS A C      1 
ATOM   875  O  O      . LYS A 1 57 ? 34.11500  3.04000   -7.30600  1.000 38.92395  ?  221 LYS A O      1 
ATOM   876  C  CB     . LYS A 1 57 ? 31.54700  3.37700   -9.40700  1.000 42.77220  ?  221 LYS A CB     1 
ATOM   877  C  CG     . LYS A 1 57 ? 30.62100  2.86800   -10.50600 1.000 45.81247  ?  221 LYS A CG     1 
ATOM   878  C  CD     . LYS A 1 57 ? 31.25900  3.03400   -11.89400 1.000 44.37647  ?  221 LYS A CD     1 
ATOM   879  C  CE     . LYS A 1 57 ? 30.23000  3.40400   -12.95500 1.000 51.86049  ?  221 LYS A CE     1 
ATOM   880  N  NZ     . LYS A 1 57 ? 29.83500  4.83400   -12.91900 1.000 53.43693  ?  221 LYS A NZ     1 
ATOM   881  H  H      . LYS A 1 57 ? 32.19400  1.15800   -8.58600  1.000 56.21877  ?  221 LYS A H      1 
ATOM   882  H  HA     . LYS A 1 57 ? 33.33800  2.85000   -10.30400 1.000 51.73756  ?  221 LYS A HA     1 
ATOM   883  H  HB2    . LYS A 1 57 ? 31.12700  3.18500   -8.55400  1.000 51.32664  ?  221 LYS A HB2    1 
ATOM   884  H  HB3    . LYS A 1 57 ? 31.63800  4.33600   -9.51900  1.000 51.32664  ?  221 LYS A HB3    1 
ATOM   885  H  HG2    . LYS A 1 57 ? 30.44200  1.92500   -10.36400 1.000 54.97496  ?  221 LYS A HG2    1 
ATOM   886  H  HG3    . LYS A 1 57 ? 29.79400  3.37400   -10.48800 1.000 54.97496  ?  221 LYS A HG3    1 
ATOM   887  H  HD2    . LYS A 1 57 ? 31.92100  3.74200   -11.85800 1.000 53.25177  ?  221 LYS A HD2    1 
ATOM   888  H  HD3    . LYS A 1 57 ? 31.67600  2.19800   -12.15500 1.000 53.25177  ?  221 LYS A HD3    1 
ATOM   889  H  HE2    . LYS A 1 57 ? 30.60200  3.22000   -13.83200 1.000 62.23259  ?  221 LYS A HE2    1 
ATOM   890  H  HE3    . LYS A 1 57 ? 29.43100  2.87200   -12.81700 1.000 62.23259  ?  221 LYS A HE3    1 
ATOM   891  H  HZ1    . LYS A 1 57 ? 29.23500  5.00000   -13.55500 1.000 64.12432  ?  221 LYS A HZ1    1 
ATOM   892  H  HZ2    . LYS A 1 57 ? 29.47900  5.03100   -12.12700 1.000 64.12432  ?  221 LYS A HZ2    1 
ATOM   893  H  HZ3    . LYS A 1 57 ? 30.54800  5.35000   -13.05300 1.000 64.12432  ?  221 LYS A HZ3    1 
ATOM   894  N  N      . LYS A 1 58 ? 34.30600  4.68200   -8.86200  1.000 41.44952  ?  222 LYS A N      1 
ATOM   895  C  CA     . LYS A 1 58 ? 34.95800  5.67400   -8.02400  1.000 39.84979  ?  222 LYS A CA     1 
ATOM   896  C  C      . LYS A 1 58 ? 33.98400  6.18100   -6.96200  1.000 42.59424  ?  222 LYS A C      1 
ATOM   897  O  O      . LYS A 1 58 ? 32.94300  6.77400   -7.27400  1.000 41.59467  ?  222 LYS A O      1 
ATOM   898  C  CB     . LYS A 1 58 ? 35.44800  6.84100   -8.87300  1.000 41.53206  ?  222 LYS A CB     1 
ATOM   899  C  CG     . LYS A 1 58 ? 36.34700  7.83700   -8.20600  1.000 46.69623  ?  222 LYS A CG     1 
ATOM   900  C  CD     . LYS A 1 58 ? 36.46100  9.14200   -9.02700  1.000 52.88941  ?  222 LYS A CD     1 
ATOM   901  C  CE     . LYS A 1 58 ? 37.74700  9.93100   -8.77700  1.000 59.67134  ?  222 LYS A CE     1 
ATOM   902  N  NZ     . LYS A 1 58 ? 38.98500  9.18700   -9.16800  1.000 67.23994  ?  222 LYS A NZ     1 
ATOM   903  H  H      . LYS A 1 58 ? 34.23700  4.93400   -9.68200  1.000 49.73942  ?  222 LYS A H      1 
ATOM   904  H  HA     . LYS A 1 58 ? 35.72100  5.27300   -7.57900  1.000 47.81975  ?  222 LYS A HA     1 
ATOM   905  H  HB2    . LYS A 1 58 ? 35.93400  6.48000   -9.63000  1.000 49.83847  ?  222 LYS A HB2    1 
ATOM   906  H  HB3    . LYS A 1 58 ? 34.67200  7.32700   -9.19400  1.000 49.83847  ?  222 LYS A HB3    1 
ATOM   907  H  HG2    . LYS A 1 58 ? 35.98800  8.05900   -7.33300  1.000 56.03547  ?  222 LYS A HG2    1 
ATOM   908  H  HG3    . LYS A 1 58 ? 37.23400  7.45600   -8.11600  1.000 56.03547  ?  222 LYS A HG3    1 
ATOM   909  H  HD2    . LYS A 1 58 ? 36.43000  8.91900   -9.97100  1.000 63.46729  ?  222 LYS A HD2    1 
ATOM   910  H  HD3    . LYS A 1 58 ? 35.71300  9.71700   -8.80200  1.000 63.46729  ?  222 LYS A HD3    1 
ATOM   911  H  HE2    . LYS A 1 58 ? 37.71700  10.75200  -9.29300  1.000 71.60561  ?  222 LYS A HE2    1 
ATOM   912  H  HE3    . LYS A 1 58 ? 37.81000  10.13800  -7.83100  1.000 71.60561  ?  222 LYS A HE3    1 
ATOM   913  H  HZ1    . LYS A 1 58 ? 39.70200  9.69400   -9.02500  1.000 80.68793  ?  222 LYS A HZ1    1 
ATOM   914  H  HZ2    . LYS A 1 58 ? 39.05700  8.44200   -8.68700  1.000 80.68793  ?  222 LYS A HZ2    1 
ATOM   915  H  HZ3    . LYS A 1 58 ? 38.95100  8.97200   -10.03100 1.000 80.68793  ?  222 LYS A HZ3    1 
ATOM   916  N  N      . MET A 1 59 ? 34.34600  5.93700   -5.72400  1.000 38.78587  ?  223 MET A N      1 
ATOM   917  C  CA     . MET A 1 59 ? 33.63500  6.49100   -4.58900  1.000 35.21481  ?  223 MET A CA     1 
ATOM   918  C  C      . MET A 1 59 ? 33.81100  7.99600   -4.55700  1.000 37.05943  ?  223 MET A C      1 
ATOM   919  O  O      . MET A 1 59 ? 34.90700  8.51200   -4.80100  1.000 42.69326  ?  223 MET A O      1 
ATOM   920  C  CB     . MET A 1 59 ? 34.18400  5.85800   -3.31800  1.000 34.66367  ?  223 MET A CB     1 
ATOM   921  C  CG     . MET A 1 59 ? 33.62000  6.49900   -2.11400  1.000 34.92643  ?  223 MET A CG     1 
ATOM   922  S  SD     . MET A 1 59 ? 31.81800  6.40300   -2.00000  1.000 35.56122  ?  223 MET A SD     1 
ATOM   923  C  CE     . MET A 1 59 ? 31.51800  4.66300   -1.93300  1.000 33.62205  ?  223 MET A CE     1 
ATOM   924  H  H      . MET A 1 59 ? 35.01500  5.44300   -5.50600  1.000 46.54304  ?  223 MET A H      1 
ATOM   925  H  HA     . MET A 1 59 ? 32.69200  6.27500   -4.66300  1.000 42.25777  ?  223 MET A HA     1 
ATOM   926  H  HB2    . MET A 1 59 ? 33.95000  4.91700   -3.30100  1.000 41.59640  ?  223 MET A HB2    1 
ATOM   927  H  HB3    . MET A 1 59 ? 35.14800  5.96500   -3.29700  1.000 41.59640  ?  223 MET A HB3    1 
ATOM   928  H  HG2    . MET A 1 59 ? 33.97900  6.04500   -1.33600  1.000 41.91172  ?  223 MET A HG2    1 
ATOM   929  H  HG3    . MET A 1 59 ? 33.87700  7.43300   -2.08300  1.000 41.91172  ?  223 MET A HG3    1 
ATOM   930  H  HE1    . MET A 1 59 ? 30.56800  4.51200   -1.80800  1.000 40.34646  ?  223 MET A HE1    1 
ATOM   931  H  HE2    . MET A 1 59 ? 31.81100  4.25900   -2.76500  1.000 40.34646  ?  223 MET A HE2    1 
ATOM   932  H  HE3    . MET A 1 59 ? 32.01300  4.28600   -1.18900  1.000 40.34646  ?  223 MET A HE3    1 
ATOM   933  N  N      . THR A 1 60 ? 32.72000  8.71300   -4.26000  1.000 36.40522  ?  224 THR A N      1 
ATOM   934  C  CA     . THR A 1 60 ? 32.69700  10.16700  -4.15800  1.000 35.16159  ?  224 THR A CA     1 
ATOM   935  C  C      . THR A 1 60 ? 32.27700  10.56900  -2.75600  1.000 33.22822  ?  224 THR A C      1 
ATOM   936  O  O      . THR A 1 60 ? 31.71400  9.76700   -2.00500  1.000 32.45680  ?  224 THR A O      1 
ATOM   937  C  CB     . THR A 1 60 ? 31.69600  10.76500  -5.14200  1.000 34.33238  ?  224 THR A CB     1 
ATOM   938  O  OG1    . THR A 1 60 ? 30.42600  10.19800  -4.83600  1.000 34.13101  ?  224 THR A OG1    1 
ATOM   939  C  CG2    . THR A 1 60 ? 32.04000  10.41700  -6.61600  1.000 38.88431  ?  224 THR A CG2    1 
ATOM   940  H  H      . THR A 1 60 ? 31.95200  8.35700   -4.10800  1.000 43.68626  ?  224 THR A H      1 
ATOM   941  H  HA     . THR A 1 60 ? 33.57800  10.53000  -4.34200  1.000 42.19390  ?  224 THR A HA     1 
ATOM   942  H  HB     . THR A 1 60 ? 31.66400  11.72900  -5.04200  1.000 41.19885  ?  224 THR A HB     1 
ATOM   943  H  HG1    . THR A 1 60 ? 29.84200  10.50200  -5.35800  1.000 40.95721  ?  224 THR A HG1    1 
ATOM   944  H  HG21   . THR A 1 60 ? 31.39000  10.82100  -7.21200  1.000 46.66118  ?  224 THR A HG21   1 
ATOM   945  H  HG22   . THR A 1 60 ? 32.92300  10.75200  -6.83800  1.000 46.66118  ?  224 THR A HG22   1 
ATOM   946  H  HG23   . THR A 1 60 ? 32.02700  9.45500   -6.74100  1.000 46.66118  ?  224 THR A HG23   1 
ATOM   947  N  N      . TYR A 1 61 ? 32.45000  11.84400  -2.41100  1.000 34.63420  ?  225 TYR A N      1 
ATOM   948  C  CA     . TYR A 1 61 ? 31.96000  12.26500  -1.09700  1.000 35.76378  ?  225 TYR A CA     1 
ATOM   949  C  C      . TYR A 1 61 ? 30.43900  12.10700  -1.00600  1.000 35.58244  ?  225 TYR A C      1 
ATOM   950  O  O      . TYR A 1 61 ? 29.90900  11.69200  0.02200   1.000 34.51005  ?  225 TYR A O      1 
ATOM   951  C  CB     . TYR A 1 61 ? 32.36400  13.70600  -0.76700  1.000 34.91022  ?  225 TYR A CB     1 
ATOM   952  C  CG     . TYR A 1 61 ? 31.64800  14.19500  0.49400   1.000 38.24701  ?  225 TYR A CG     1 
ATOM   953  C  CD1    . TYR A 1 61 ? 32.11400  13.86000  1.78500   1.000 38.09446  ?  225 TYR A CD1    1 
ATOM   954  C  CD2    . TYR A 1 61 ? 30.50000  14.94300  0.39700   1.000 36.18454  ?  225 TYR A CD2    1 
ATOM   955  C  CE1    . TYR A 1 61 ? 31.41600  14.29200  2.93400   1.000 42.20385  ?  225 TYR A CE1    1 
ATOM   956  C  CE2    . TYR A 1 61 ? 29.80600  15.36700  1.51900   1.000 35.86091  ?  225 TYR A CE2    1 
ATOM   957  C  CZ     . TYR A 1 61 ? 30.26800  15.02200  2.78800   1.000 40.07012  ?  225 TYR A CZ     1 
ATOM   958  O  OH     . TYR A 1 61 ? 29.57700  15.42200  3.88400   1.000 44.22836  ?  225 TYR A OH     1 
ATOM   959  H  H      . TYR A 1 61 ? 32.82500  12.45400  -2.88700  1.000 41.56105  ?  225 TYR A H      1 
ATOM   960  H  HA     . TYR A 1 61 ? 32.35400  11.69000  -0.42300  1.000 42.91654  ?  225 TYR A HA     1 
ATOM   961  H  HB2    . TYR A 1 61 ? 33.32100  13.74500  -0.61100  1.000 41.89226  ?  225 TYR A HB2    1 
ATOM   962  H  HB3    . TYR A 1 61 ? 32.11800  14.28700  -1.50400  1.000 41.89226  ?  225 TYR A HB3    1 
ATOM   963  H  HD1    . TYR A 1 61 ? 32.88400  13.34700  1.87900   1.000 45.71336  ?  225 TYR A HD1    1 
ATOM   964  H  HD2    . TYR A 1 61 ? 30.17300  15.16100  -0.44600  1.000 43.42145  ?  225 TYR A HD2    1 
ATOM   965  H  HE1    . TYR A 1 61 ? 31.72100  14.06200  3.78200   1.000 50.64461  ?  225 TYR A HE1    1 
ATOM   966  H  HE2    . TYR A 1 61 ? 29.02600  15.86500  1.42500   1.000 43.03309  ?  225 TYR A HE2    1 
ATOM   967  H  HH     . TYR A 1 61 ? 28.89800  15.85900  3.65200   1.000 53.07403  ?  225 TYR A HH     1 
ATOM   968  N  N      . GLN A 1 62 ? 29.71600  12.38200  -2.08500  1.000 35.35851  ?  226 GLN A N      1 
ATOM   969  C  CA     A GLN A 1 62 ? 28.25500  12.33500  -2.01600  0.585 35.28431  ?  226 GLN A CA     1 
ATOM   970  C  CA     B GLN A 1 62 ? 28.25100  12.33800  -1.97000  0.415 36.10164  ?  226 GLN A CA     1 
ATOM   971  C  C      . GLN A 1 62 ? 27.76700  10.92300  -1.72000  1.000 33.37998  ?  226 GLN A C      1 
ATOM   972  O  O      . GLN A 1 62 ? 26.81000  10.72500  -0.94800  1.000 32.45708  ?  226 GLN A O      1 
ATOM   973  C  CB     A GLN A 1 62 ? 27.73600  12.85900  -3.36700  0.585 38.18006  ?  226 GLN A CB     1 
ATOM   974  C  CB     B GLN A 1 62 ? 27.56100  12.93000  -3.20000  0.415 38.23343  ?  226 GLN A CB     1 
ATOM   975  C  CG     A GLN A 1 62 ? 26.26800  12.98900  -3.48200  0.585 38.21659  ?  226 GLN A CG     1 
ATOM   976  C  CG     B GLN A 1 62 ? 26.00100  12.93000  -3.02800  0.415 37.56278  ?  226 GLN A CG     1 
ATOM   977  C  CD     A GLN A 1 62 ? 25.92900  13.67400  -4.77200  0.585 37.84533  ?  226 GLN A CD     1 
ATOM   978  C  CD     B GLN A 1 62 ? 25.42000  13.79900  -1.87500  0.415 39.06251  ?  226 GLN A CD     1 
ATOM   979  O  OE1    A GLN A 1 62 ? 26.80800  14.25600  -5.42100  0.585 42.29841  ?  226 GLN A OE1    1 
ATOM   980  O  OE1    B GLN A 1 62 ? 25.55000  13.49600  -0.60100  0.415 35.79423  ?  226 GLN A OE1    1 
ATOM   981  N  NE2    A GLN A 1 62 ? 24.66300  13.61200  -5.16400  0.585 29.84831  ?  226 GLN A NE2    1 
ATOM   982  N  NE2    B GLN A 1 62 ? 24.69800  14.85900  -2.30600  0.415 34.26435  ?  226 GLN A NE2    1 
ATOM   983  H  H      A GLN A 1 62 ? 30.03500  12.59400  -2.85500  0.585 42.43021  ?  226 GLN A H      1 
ATOM   984  H  H      B GLN A 1 62 ? 30.02400  12.58800  -2.86100  0.415 42.43021  ?  226 GLN A H      1 
ATOM   985  H  HA     A GLN A 1 62 ? 27.94200  12.92500  -1.31300  0.585 42.34117  ?  226 GLN A HA     1 
ATOM   986  H  HA     B GLN A 1 62 ? 27.98900  12.87300  -1.20500  0.415 43.32197  ?  226 GLN A HA     1 
ATOM   987  H  HB2    A GLN A 1 62 ? 28.12000  13.73700  -3.51700  0.585 45.81607  ?  226 GLN A HB2    1 
ATOM   988  H  HB2    B GLN A 1 62 ? 27.85400  13.84600  -3.32300  0.415 45.88012  ?  226 GLN A HB2    1 
ATOM   989  H  HB3    A GLN A 1 62 ? 28.03000  12.25300  -4.06500  0.585 45.81607  ?  226 GLN A HB3    1 
ATOM   990  H  HB3    B GLN A 1 62 ? 27.78200  12.39700  -3.98000  0.415 45.88012  ?  226 GLN A HB3    1 
ATOM   991  H  HG2    A GLN A 1 62 ? 25.86100  12.10900  -3.48100  0.585 45.85990  ?  226 GLN A HG2    1 
ATOM   992  H  HG2    B GLN A 1 62 ? 25.61200  13.26000  -3.85300  0.415 45.07534  ?  226 GLN A HG2    1 
ATOM   993  H  HG3    A GLN A 1 62 ? 25.92900  13.52400  -2.74800  0.585 45.85990  ?  226 GLN A HG3    1 
ATOM   994  H  HG3    B GLN A 1 62 ? 25.70200  12.01900  -2.88200  0.415 45.07534  ?  226 GLN A HG3    1 
ATOM   995  H  HE21   A GLN A 1 62 ? 24.08400  13.19600  -4.68300  0.585 35.81797  ?  226 GLN A HE21   1 
ATOM   996  H  HE21   B GLN A 1 62 ? 24.62600  15.01700  -3.14800  0.415 41.11722  ?  226 GLN A HE21   1 
ATOM   997  H  HE22   A GLN A 1 62 ? 24.42100  13.99000  -5.89800  0.585 35.81797  ?  226 GLN A HE22   1 
ATOM   998  H  HE22   B GLN A 1 62 ? 24.33500  15.39200  -1.73700  0.415 41.11722  ?  226 GLN A HE22   1 
ATOM   999  N  N      . LYS A 1 63 ? 28.40200  9.90400   -2.33100  1.000 29.44513  ?  227 LYS A N      1 
ATOM   1000 C  CA     . LYS A 1 63 ? 27.97700  8.53200   -2.08900  1.000 29.64276  ?  227 LYS A CA     1 
ATOM   1001 C  C      . LYS A 1 63 ? 28.36200  8.06600   -0.67800  1.000 31.34929  ?  227 LYS A C      1 
ATOM   1002 O  O      . LYS A 1 63 ? 27.60300  7.33900   0.00900   1.000 28.37217  ?  227 LYS A O      1 
ATOM   1003 C  CB     . LYS A 1 63 ? 28.57400  7.61200   -3.15100  1.000 33.41714  ?  227 LYS A CB     1 
ATOM   1004 C  CG     . LYS A 1 63 ? 27.86500  7.75100   -4.55200  1.000 32.01770  ?  227 LYS A CG     1 
ATOM   1005 C  CD     . LYS A 1 63 ? 28.31300  6.65100   -5.48800  1.000 30.54771  ?  227 LYS A CD     1 
ATOM   1006 C  CE     . LYS A 1 63 ? 29.73700  6.97000   -6.04400  1.000 35.70618  ?  227 LYS A CE     1 
ATOM   1007 N  NZ     . LYS A 1 63 ? 30.32500  5.89600   -6.85900  1.000 36.62887  ?  227 LYS A NZ     1 
ATOM   1008 H  H      . LYS A 1 63 ? 29.06300  9.98700   -2.87400  1.000 35.33415  ?  227 LYS A H      1 
ATOM   1009 H  HA     . LYS A 1 63 ? 27.01100  8.48500   -2.16400  1.000 35.57132  ?  227 LYS A HA     1 
ATOM   1010 H  HB2    . LYS A 1 63 ? 29.51200  7.83100   -3.26600  1.000 40.10056  ?  227 LYS A HB2    1 
ATOM   1011 H  HB3    . LYS A 1 63 ? 28.48200  6.69200   -2.85800  1.000 40.10056  ?  227 LYS A HB3    1 
ATOM   1012 H  HG2    . LYS A 1 63 ? 26.90400  7.68300   -4.43600  1.000 38.42124  ?  227 LYS A HG2    1 
ATOM   1013 H  HG3    . LYS A 1 63 ? 28.09900  8.60500   -4.94900  1.000 38.42124  ?  227 LYS A HG3    1 
ATOM   1014 H  HD2    . LYS A 1 63 ? 28.35100  5.81000   -5.00700  1.000 36.65725  ?  227 LYS A HD2    1 
ATOM   1015 H  HD3    . LYS A 1 63 ? 27.69700  6.58900   -6.23500  1.000 36.65725  ?  227 LYS A HD3    1 
ATOM   1016 H  HE2    . LYS A 1 63 ? 29.68300  7.76400   -6.59800  1.000 42.84742  ?  227 LYS A HE2    1 
ATOM   1017 H  HE3    . LYS A 1 63 ? 30.33400  7.13200   -5.29700  1.000 42.84742  ?  227 LYS A HE3    1 
ATOM   1018 H  HZ1    . LYS A 1 63 ? 31.13200  6.13800   -7.14400  1.000 43.95465  ?  227 LYS A HZ1    1 
ATOM   1019 H  HZ2    . LYS A 1 63 ? 30.40000  5.15300   -6.37400  1.000 43.95465  ?  227 LYS A HZ2    1 
ATOM   1020 H  HZ3    . LYS A 1 63 ? 29.80700  5.73100   -7.56300  1.000 43.95465  ?  227 LYS A HZ3    1 
ATOM   1021 N  N      . MET A 1 64 ? 29.52500  8.50700   -0.21900  1.000 30.88663  ?  228 MET A N      1 
ATOM   1022 C  CA     . MET A 1 64 ? 29.93000  8.21000   1.14900   1.000 35.70235  ?  228 MET A CA     1 
ATOM   1023 C  C      . MET A 1 64 ? 28.98100  8.83300   2.15800   1.000 32.07348  ?  228 MET A C      1 
ATOM   1024 O  O      . MET A 1 64 ? 28.52300  8.13500   3.06700   1.000 32.54828  ?  228 MET A O      1 
ATOM   1025 C  CB     . MET A 1 64 ? 31.37400  8.66000   1.37800   1.000 33.39717  ?  228 MET A CB     1 
ATOM   1026 C  CG     . MET A 1 64 ? 31.83800  8.48200   2.85500   1.000 37.85251  ?  228 MET A CG     1 
ATOM   1027 S  SD     . MET A 1 64 ? 33.53900  9.08600   3.00000   1.000 40.34072  ?  228 MET A SD     1 
ATOM   1028 C  CE     . MET A 1 64 ? 34.35700  7.52200   3.29300   1.000 51.00514  ?  228 MET A CE     1 
ATOM   1029 H  H      . MET A 1 64 ? 30.09000  8.97300   -0.67000  1.000 37.06395  ?  228 MET A H      1 
ATOM   1030 H  HA     . MET A 1 64 ? 29.90800  7.24800   1.26800   1.000 42.84282  ?  228 MET A HA     1 
ATOM   1031 H  HB2    . MET A 1 64 ? 31.96200  8.13300   0.81400   1.000 40.07660  ?  228 MET A HB2    1 
ATOM   1032 H  HB3    . MET A 1 64 ? 31.45100  9.60000   1.15100   1.000 40.07660  ?  228 MET A HB3    1 
ATOM   1033 H  HG2    . MET A 1 64 ? 31.27800  9.01200   3.44300   1.000 45.42301  ?  228 MET A HG2    1 
ATOM   1034 H  HG3    . MET A 1 64 ? 31.80200  7.54600   3.10200   1.000 45.42301  ?  228 MET A HG3    1 
ATOM   1035 H  HE1    . MET A 1 64 ? 35.16600  7.50100   2.76000   1.000 61.20616  ?  228 MET A HE1    1 
ATOM   1036 H  HE2    . MET A 1 64 ? 34.58700  7.45600   4.23200   1.000 61.20616  ?  228 MET A HE2    1 
ATOM   1037 H  HE3    . MET A 1 64 ? 33.77500  6.79500   3.03100   1.000 61.20616  ?  228 MET A HE3    1 
ATOM   1038 N  N      . ALA A 1 65 ? 28.65800  10.13300  2.01400   1.000 31.05050  ?  229 ALA A N      1 
ATOM   1039 C  CA     . ALA A 1 65 ? 27.63000  10.73400  2.87300   1.000 32.22072  ?  229 ALA A CA     1 
ATOM   1040 C  C      . ALA A 1 65 ? 26.29600  10.00500  2.76500   1.000 32.01171  ?  229 ALA A C      1 
ATOM   1041 O  O      . ALA A 1 65 ? 25.54600  9.93000   3.74600   1.000 28.06245  ?  229 ALA A O      1 
ATOM   1042 C  CB     . ALA A 1 65 ? 27.38900  12.20900  2.56600   1.000 35.00701  ?  229 ALA A CB     1 
ATOM   1043 H  H      . ALA A 1 65 ? 29.01100  10.67000  1.44200   1.000 37.26060  ?  229 ALA A H      1 
ATOM   1044 H  HA     . ALA A 1 65 ? 27.93100  10.67800  3.79000   1.000 38.66486  ?  229 ALA A HA     1 
ATOM   1045 H  HB1    . ALA A 1 65 ? 26.70300  12.54700  3.16300   1.000 42.00841  ?  229 ALA A HB1    1 
ATOM   1046 H  HB2    . ALA A 1 65 ? 28.21600  12.69800  2.70000   1.000 42.00841  ?  229 ALA A HB2    1 
ATOM   1047 H  HB3    . ALA A 1 65 ? 27.09900  12.29600  1.64500   1.000 42.00841  ?  229 ALA A HB3    1 
ATOM   1048 N  N      . ARG A 1 66 ? 25.97700  9.43400   1.60600   1.000 30.50625  ?  230 ARG A N      1 
ATOM   1049 C  CA     . ARG A 1 66 ? 24.72400  8.69600   1.53800   1.000 30.96568  ?  230 ARG A CA     1 
ATOM   1050 C  C      . ARG A 1 66 ? 24.76400  7.54500   2.50800   1.000 28.08854  ?  230 ARG A C      1 
ATOM   1051 O  O      . ARG A 1 66 ? 23.77500  7.26400   3.19400   1.000 31.48334  ?  230 ARG A O      1 
ATOM   1052 C  CB     . ARG A 1 66 ? 24.44800  8.19000   0.10700   1.000 28.94561  ?  230 ARG A CB     1 
ATOM   1053 C  CG     . ARG A 1 66 ? 23.19300  7.31600   -0.01200  1.000 26.40686  ?  230 ARG A CG     1 
ATOM   1054 C  CD     . ARG A 1 66 ? 22.00400  8.17400   0.08600   1.000 29.99260  ?  230 ARG A CD     1 
ATOM   1055 N  NE     . ARG A 1 66 ? 20.76000  7.41400   0.03000   1.000 33.43884  ?  230 ARG A NE     1 
ATOM   1056 C  CZ     . ARG A 1 66 ? 20.17700  6.84100   1.06700   1.000 36.67211  ?  230 ARG A CZ     1 
ATOM   1057 N  NH1    . ARG A 1 66 ? 20.73400  6.89100   2.27900   1.000 32.56901  ?  230 ARG A NH1    1 
ATOM   1058 N  NH2    . ARG A 1 66 ? 19.01400  6.19600   0.87700   1.000 37.11723  ?  230 ARG A NH2    1 
ATOM   1059 H  H      . ARG A 1 66 ? 26.44100  9.45600   0.88200   1.000 36.60750  ?  230 ARG A H      1 
ATOM   1060 H  HA     . ARG A 1 66 ? 23.99700  9.28400   1.79700   1.000 37.15882  ?  230 ARG A HA     1 
ATOM   1061 H  HB2    . ARG A 1 66 ? 24.33300  8.95500   -0.47800  1.000 34.73473  ?  230 ARG A HB2    1 
ATOM   1062 H  HB3    . ARG A 1 66 ? 25.20500  7.66100   -0.18900  1.000 34.73473  ?  230 ARG A HB3    1 
ATOM   1063 H  HG2    . ARG A 1 66 ? 23.18500  6.88000   -0.87800  1.000 31.68823  ?  230 ARG A HG2    1 
ATOM   1064 H  HG3    . ARG A 1 66 ? 23.16400  6.65700   0.69800   1.000 31.68823  ?  230 ARG A HG3    1 
ATOM   1065 H  HD2    . ARG A 1 66 ? 22.02400  8.65600   0.92700   1.000 35.99112  ?  230 ARG A HD2    1 
ATOM   1066 H  HD3    . ARG A 1 66 ? 22.00500  8.80000   -0.65500  1.000 35.99112  ?  230 ARG A HD3    1 
ATOM   1067 H  HE     . ARG A 1 66 ? 20.37800  7.33300   -0.73600  1.000 40.12661  ?  230 ARG A HE     1 
ATOM   1068 H  HH11   . ARG A 1 66 ? 21.47800  7.30400   2.39800   1.000 39.08281  ?  230 ARG A HH11   1 
ATOM   1069 H  HH12   . ARG A 1 66 ? 20.34400  6.51100   2.94500   1.000 39.08281  ?  230 ARG A HH12   1 
ATOM   1070 H  HH21   . ARG A 1 66 ? 18.66200  6.16600   0.09300   1.000 44.54068  ?  230 ARG A HH21   1 
ATOM   1071 H  HH22   . ARG A 1 66 ? 18.62100  5.81400   1.54000   1.000 44.54068  ?  230 ARG A HH22   1 
ATOM   1072 N  N      . ALA A 1 67 ? 25.87200  6.81800   2.52400   1.000 30.73675  ?  231 ALA A N      1 
ATOM   1073 C  CA     . ALA A 1 67 ? 26.03900  5.77300   3.52800   1.000 33.06795  ?  231 ALA A CA     1 
ATOM   1074 C  C      . ALA A 1 67 ? 26.03500  6.37500   4.92400   1.000 30.70351  ?  231 ALA A C      1 
ATOM   1075 O  O      . ALA A 1 67 ? 25.37700  5.86700   5.82000   1.000 33.65820  ?  231 ALA A O      1 
ATOM   1076 C  CB     . ALA A 1 67 ? 27.33200  5.00100   3.34400   1.000 33.17197  ?  231 ALA A CB     1 
ATOM   1077 H  H      . ALA A 1 67 ? 26.53100  6.90500   1.97800   1.000 36.88410  ?  231 ALA A H      1 
ATOM   1078 H  HA     . ALA A 1 67 ? 25.30000  5.14800   3.46400   1.000 39.68154  ?  231 ALA A HA     1 
ATOM   1079 H  HB1    . ALA A 1 67 ? 27.40400  4.33600   4.04600   1.000 39.80636  ?  231 ALA A HB1    1 
ATOM   1080 H  HB2    . ALA A 1 67 ? 27.32000  4.56700   2.47700   1.000 39.80636  ?  231 ALA A HB2    1 
ATOM   1081 H  HB3    . ALA A 1 67 ? 28.07800  5.61900   3.39600   1.000 39.80636  ?  231 ALA A HB3    1 
ATOM   1082 N  N      . LEU A 1 68 ? 26.76500  7.44900   5.11600   1.000 30.13885  ?  232 LEU A N      1 
ATOM   1083 C  CA     . LEU A 1 68 ? 26.84500  8.02600   6.45600   1.000 34.70705  ?  232 LEU A CA     1 
ATOM   1084 C  C      . LEU A 1 68 ? 25.45400  8.29700   7.01700   1.000 37.28977  ?  232 LEU A C      1 
ATOM   1085 O  O      . LEU A 1 68 ? 25.20100  8.01200   8.17600   1.000 38.45818  ?  232 LEU A O      1 
ATOM   1086 C  CB     . LEU A 1 68 ? 27.67900  9.30800   6.44500   1.000 34.00284  ?  232 LEU A CB     1 
ATOM   1087 C  CG     . LEU A 1 68 ? 29.17300  9.02000   6.52600   1.000 32.78660  ?  232 LEU A CG     1 
ATOM   1088 C  CD1    . LEU A 1 68 ? 29.96100  10.35800  6.47500   1.000 32.29572  ?  232 LEU A CD1    1 
ATOM   1089 C  CD2    . LEU A 1 68 ? 29.56100  8.15900   7.80700   1.000 38.84328  ?  232 LEU A CD2    1 
ATOM   1090 H  H      . LEU A 1 68 ? 27.21700  7.86100   4.51100   1.000 36.16662  ?  232 LEU A H      1 
ATOM   1091 H  HA     . LEU A 1 68 ? 27.26600  7.38100   7.04200   1.000 41.64846  ?  232 LEU A HA     1 
ATOM   1092 H  HB2    . LEU A 1 68 ? 27.50300  9.79300   5.62700   1.000 40.80341  ?  232 LEU A HB2    1 
ATOM   1093 H  HB3    . LEU A 1 68 ? 27.43600  9.85000   7.21200   1.000 40.80341  ?  232 LEU A HB3    1 
ATOM   1094 H  HG     . LEU A 1 68 ? 29.42700  8.50500   5.74400   1.000 39.34392  ?  232 LEU A HG     1 
ATOM   1095 H  HD11   . LEU A 1 68 ? 30.91100  10.16700  6.52700   1.000 38.75486  ?  232 LEU A HD11   1 
ATOM   1096 H  HD12   . LEU A 1 68 ? 29.75900  10.81100  5.64100   1.000 38.75486  ?  232 LEU A HD12   1 
ATOM   1097 H  HD13   . LEU A 1 68 ? 29.69300  10.91100  7.22600   1.000 38.75486  ?  232 LEU A HD13   1 
ATOM   1098 H  HD21   . LEU A 1 68 ? 30.49900  8.30100   8.01000   1.000 46.61194  ?  232 LEU A HD21   1 
ATOM   1099 H  HD22   . LEU A 1 68 ? 29.01400  8.44400   8.55500   1.000 46.61194  ?  232 LEU A HD22   1 
ATOM   1100 H  HD23   . LEU A 1 68 ? 29.40200  7.22100   7.61900   1.000 46.61194  ?  232 LEU A HD23   1 
ATOM   1101 N  N      . ARG A 1 69 ? 24.52500  8.77600   6.17400   1.000 32.86577  ?  233 ARG A N      1 
ATOM   1102 C  CA     . ARG A 1 69 ? 23.19900  9.14900   6.62900   1.000 38.39062  ?  233 ARG A CA     1 
ATOM   1103 C  C      . ARG A 1 69 ? 22.42700  7.94600   7.14900   1.000 38.77988  ?  233 ARG A C      1 
ATOM   1104 O  O      . ARG A 1 69 ? 21.60200  8.09500   8.06300   1.000 35.96187  ?  233 ARG A O      1 
ATOM   1105 C  CB     . ARG A 1 69 ? 22.38000  9.80200   5.49800   1.000 35.51671  ?  233 ARG A CB     1 
ATOM   1106 C  CG     . ARG A 1 69 ? 22.76600  11.26300  5.24400   1.000 39.30173  ?  233 ARG A CG     1 
ATOM   1107 C  CD     . ARG A 1 69 ? 21.68500  12.04000  4.52200   1.000 37.74323  ?  233 ARG A CD     1 
ATOM   1108 N  NE     . ARG A 1 69 ? 21.57900  11.59000  3.14300   1.000 35.39688  ?  233 ARG A NE     1 
ATOM   1109 C  CZ     . ARG A 1 69 ? 22.44200  11.87900  2.16300   1.000 33.74620  ?  233 ARG A CZ     1 
ATOM   1110 N  NH1    . ARG A 1 69 ? 23.49300  12.65700  2.35500   1.000 31.93227  ?  233 ARG A NH1    1 
ATOM   1111 N  NH2    . ARG A 1 69 ? 22.22100  11.39600  0.94500   1.000 30.49269  ?  233 ARG A NH2    1 
ATOM   1112 H  H      . ARG A 1 69 ? 24.65000  8.89100   5.33100   1.000 39.43892  ?  233 ARG A H      1 
ATOM   1113 H  HA     . ARG A 1 69 ? 23.28100  9.79000   7.35200   1.000 46.06875  ?  233 ARG A HA     1 
ATOM   1114 H  HB2    . ARG A 1 69 ? 22.52700  9.30700   4.67700   1.000 42.62005  ?  233 ARG A HB2    1 
ATOM   1115 H  HB3    . ARG A 1 69 ? 21.44000  9.77800   5.73600   1.000 42.62005  ?  233 ARG A HB3    1 
ATOM   1116 H  HG2    . ARG A 1 69 ? 22.93000  11.69900  6.09500   1.000 47.16208  ?  233 ARG A HG2    1 
ATOM   1117 H  HG3    . ARG A 1 69 ? 23.56800  11.28700  4.69900   1.000 47.16208  ?  233 ARG A HG3    1 
ATOM   1118 H  HD2    . ARG A 1 69 ? 20.83200  11.89400  4.96000   1.000 45.29187  ?  233 ARG A HD2    1 
ATOM   1119 H  HD3    . ARG A 1 69 ? 21.91000  12.98400  4.52200   1.000 45.29187  ?  233 ARG A HD3    1 
ATOM   1120 H  HE     . ARG A 1 69 ? 20.90400  11.09600  2.94100   1.000 42.47625  ?  233 ARG A HE     1 
ATOM   1121 H  HH11   . ARG A 1 69 ? 23.65100  12.98300  3.13500   1.000 38.31873  ?  233 ARG A HH11   1 
ATOM   1122 H  HH12   . ARG A 1 69 ? 24.02600  12.82700  1.70200   1.000 38.31873  ?  233 ARG A HH12   1 
ATOM   1123 H  HH21   . ARG A 1 69 ? 21.54000  10.89200  0.80000   1.000 36.59123  ?  233 ARG A HH21   1 
ATOM   1124 H  HH22   . ARG A 1 69 ? 22.76600  11.57800  0.30500   1.000 36.59123  ?  233 ARG A HH22   1 
ATOM   1125 N  N      . ASN A 1 70 ? 22.69100  6.75400   6.58400   1.000 34.57672  ?  234 ASN A N      1 
ATOM   1126 C  CA     . ASN A 1 70 ? 22.08400  5.53900   7.10800   1.000 40.71246  ?  234 ASN A CA     1 
ATOM   1127 C  C      . ASN A 1 70 ? 22.50000  5.24100   8.55500   1.000 40.02463  ?  234 ASN A C      1 
ATOM   1128 O  O      . ASN A 1 70 ? 21.79900  4.51800   9.24900   1.000 43.10928  ?  234 ASN A O      1 
ATOM   1129 C  CB     . ASN A 1 70 ? 22.44800  4.37000   6.20900   1.000 34.05430  ?  234 ASN A CB     1 
ATOM   1130 C  CG     . ASN A 1 70 ? 21.66500  4.41300   4.86400   1.000 40.49652  ?  234 ASN A CG     1 
ATOM   1131 O  OD1    . ASN A 1 70 ? 20.64800  5.10000   4.75000   1.000 46.20571  ?  234 ASN A OD1    1 
ATOM   1132 N  ND2    . ASN A 1 70 ? 22.13400  3.68100   3.86700   1.000 38.26767  ?  234 ASN A ND2    1 
ATOM   1133 H  H      . ASN A 1 70 ? 23.21000  6.63300   5.90900   1.000 41.49207  ?  234 ASN A H      1 
ATOM   1134 H  HA     . ASN A 1 70 ? 21.12100  5.64200   7.09100   1.000 48.85495  ?  234 ASN A HA     1 
ATOM   1135 H  HB2    . ASN A 1 70 ? 23.39600  4.40300   6.00900   1.000 40.86516  ?  234 ASN A HB2    1 
ATOM   1136 H  HB3    . ASN A 1 70 ? 22.22900  3.54000   6.66100   1.000 40.86516  ?  234 ASN A HB3    1 
ATOM   1137 H  HD21   . ASN A 1 70 ? 21.72900  3.67800   3.10800   1.000 45.92120  ?  234 ASN A HD21   1 
ATOM   1138 H  HD22   . ASN A 1 70 ? 22.84500  3.21100   3.97700   1.000 45.92120  ?  234 ASN A HD22   1 
ATOM   1139 N  N      . TYR A 1 71 ? 23.63600  5.73400   9.01100   1.000 35.47810  ?  235 TYR A N      1 
ATOM   1140 C  CA     . TYR A 1 71 ? 23.99000  5.47500   10.39600  1.000 40.40420  ?  235 TYR A CA     1 
ATOM   1141 C  C      . TYR A 1 71 ? 23.07800  6.25300   11.33000  1.000 42.54262  ?  235 TYR A C      1 
ATOM   1142 O  O      . TYR A 1 71 ? 22.92600  5.85800   12.46000  1.000 44.58949  ?  235 TYR A O      1 
ATOM   1143 C  CB     . TYR A 1 71 ? 25.46300  5.81800   10.65700  1.000 36.55611  ?  235 TYR A CB     1 
ATOM   1144 C  CG     . TYR A 1 71 ? 26.46100  4.81400   10.08500  1.000 35.72936  ?  235 TYR A CG     1 
ATOM   1145 C  CD1    . TYR A 1 71 ? 26.21700  3.42900   10.12500  1.000 35.08892  ?  235 TYR A CD1    1 
ATOM   1146 C  CD2    . TYR A 1 71 ? 27.65700  5.26300   9.51400   1.000 35.71593  ?  235 TYR A CD2    1 
ATOM   1147 C  CE1    . TYR A 1 71 ? 27.14300  2.53300   9.62700   1.000 39.40345  ?  235 TYR A CE1    1 
ATOM   1148 C  CE2    . TYR A 1 71 ? 28.60700  4.36100   8.99500   1.000 39.72688  ?  235 TYR A CE2    1 
ATOM   1149 C  CZ     . TYR A 1 71 ? 28.34500  3.01600   9.04900   1.000 40.51183  ?  235 TYR A CZ     1 
ATOM   1150 O  OH     . TYR A 1 71 ? 29.30100  2.18500   8.56000   1.000 42.22651  ?  235 TYR A OH     1 
ATOM   1151 H  H      . TYR A 1 71 ? 24.20000  6.20300   8.56300   1.000 42.57372  ?  235 TYR A H      1 
ATOM   1152 H  HA     . TYR A 1 71 ? 23.85700  4.53300   10.58300  1.000 48.48504  ?  235 TYR A HA     1 
ATOM   1153 H  HB2    . TYR A 1 71 ? 25.65500  6.68200   10.26000  1.000 43.86733  ?  235 TYR A HB2    1 
ATOM   1154 H  HB3    . TYR A 1 71 ? 25.60600  5.86000   11.61500  1.000 43.86733  ?  235 TYR A HB3    1 
ATOM   1155 H  HD1    . TYR A 1 71 ? 25.43100  3.11100   10.50700  1.000 42.10670  ?  235 TYR A HD1    1 
ATOM   1156 H  HD2    . TYR A 1 71 ? 27.83200  6.17600   9.48300   1.000 42.85911  ?  235 TYR A HD2    1 
ATOM   1157 H  HE1    . TYR A 1 71 ? 26.97500  1.61900   9.66100   1.000 47.28414  ?  235 TYR A HE1    1 
ATOM   1158 H  HE2    . TYR A 1 71 ? 29.40100  4.67300   8.62400   1.000 47.67226  ?  235 TYR A HE2    1 
ATOM   1159 H  HH     . TYR A 1 71 ? 29.12600  1.39200   8.77200   1.000 50.67181  ?  235 TYR A HH     1 
ATOM   1160 N  N      . GLY A 1 72 ? 22.44300  7.31500   10.84900  1.000 42.64138  ?  236 GLY A N      1 
ATOM   1161 C  CA     . GLY A 1 72 ? 21.46700  8.03100   11.63400  1.000 43.33021  ?  236 GLY A CA     1 
ATOM   1162 C  C      . GLY A 1 72 ? 20.35300  7.15200   12.17000  1.000 44.98506  ?  236 GLY A C      1 
ATOM   1163 O  O      . GLY A 1 72 ? 19.79600  7.42600   13.24100  1.000 53.36866  ?  236 GLY A O      1 
ATOM   1164 H  H      . GLY A 1 72 ? 22.56600  7.64000   10.06200  1.000 51.16965  ?  236 GLY A H      1 
ATOM   1165 H  HA2    . GLY A 1 72 ? 21.91000  8.45200   12.38700  1.000 51.99625  ?  236 GLY A HA2    1 
ATOM   1166 H  HA3    . GLY A 1 72 ? 21.06800  8.72700   11.08900  1.000 51.99625  ?  236 GLY A HA3    1 
ATOM   1167 N  N      . LYS A 1 73 ? 19.99500  6.09400   11.46600  1.000 44.48832  ?  237 LYS A N      1 
ATOM   1168 C  CA     . LYS A 1 73 ? 18.91300  5.18600   11.91500  1.000 51.97823  ?  237 LYS A CA     1 
ATOM   1169 C  C      . LYS A 1 73 ? 19.40800  4.35600   13.09500  1.000 54.50239  ?  237 LYS A C      1 
ATOM   1170 O  O      . LYS A 1 73 ? 18.68600  4.28800   14.09800  0.563 57.25559  ?  237 LYS A O      1 
ATOM   1171 C  CB     . LYS A 1 73 ? 18.47600  4.27300   10.77000  1.000 54.99065  ?  237 LYS A CB     1 
ATOM   1172 C  CG     . LYS A 1 73 ? 17.65800  4.96000   9.68800   0.000 50.92274  ?  237 LYS A CG     1 
ATOM   1173 C  CD     . LYS A 1 73 ? 17.57300  4.15800   8.41600   1.000 57.04161  ?  237 LYS A CD     1 
ATOM   1174 C  CE     . LYS A 1 73 ? 18.82200  4.27300   7.57300   1.000 57.98428  ?  237 LYS A CE     1 
ATOM   1175 N  NZ     . LYS A 1 73 ? 18.66200  3.59700   6.26600   0.000 45.11152  ?  237 LYS A NZ     1 
ATOM   1176 H  H      . LYS A 1 73 ? 20.35500  5.86500   10.71900  1.000 53.38599  ?  237 LYS A H      1 
ATOM   1177 H  HA     . LYS A 1 73 ? 18.14800  5.70900   12.20300  1.000 62.37387  ?  237 LYS A HA     1 
ATOM   1178 H  HB2    . LYS A 1 73 ? 19.26800  3.90300   10.35000  1.000 65.98878  ?  237 LYS A HB2    1 
ATOM   1179 H  HB3    . LYS A 1 73 ? 17.93500  3.55500   11.13500  1.000 65.98878  ?  237 LYS A HB3    1 
ATOM   1180 H  HG2    . LYS A 1 73 ? 16.75500  5.09800   10.01500  0.000 61.10728  ?  237 LYS A HG2    1 
ATOM   1181 H  HG3    . LYS A 1 73 ? 18.06800  5.81300   9.47700   0.000 61.10728  ?  237 LYS A HG3    1 
ATOM   1182 H  HD2    . LYS A 1 73 ? 17.44600  3.22300   8.63900   1.000 68.44994  ?  237 LYS A HD2    1 
ATOM   1183 H  HD3    . LYS A 1 73 ? 16.82400  4.47800   7.88900   1.000 68.44994  ?  237 LYS A HD3    1 
ATOM   1184 H  HE2    . LYS A 1 73 ? 19.00300  5.21100   7.40700   1.000 69.58114  ?  237 LYS A HE2    1 
ATOM   1185 H  HE3    . LYS A 1 73 ? 19.56600  3.86200   8.04100   1.000 69.58114  ?  237 LYS A HE3    1 
ATOM   1186 H  HZ1    . LYS A 1 73 ? 19.41700  3.65500   5.79900   0.000 54.13382  ?  237 LYS A HZ1    1 
ATOM   1187 H  HZ2    . LYS A 1 73 ? 18.46400  2.73800   6.39100   0.000 54.13382  ?  237 LYS A HZ2    1 
ATOM   1188 H  HZ3    . LYS A 1 73 ? 18.00500  3.98100   5.80400   0.000 54.13382  ?  237 LYS A HZ3    1 
ATOM   1189 N  N      . THR A 1 74 ? 20.58800  3.76400   12.98300  1.000 59.10168  ?  238 THR A N      1 
ATOM   1190 C  CA     . THR A 1 74 ? 21.17100  2.88000   14.02000  1.000 57.73261  ?  238 THR A CA     1 
ATOM   1191 C  C      . THR A 1 74 ? 21.73600  3.72600   15.16100  1.000 53.24817  ?  238 THR A C      1 
ATOM   1192 O  O      . THR A 1 74 ? 21.35400  3.45300   16.29600  1.000 64.51987  ?  238 THR A O      1 
ATOM   1193 C  CB     . THR A 1 74 ? 22.19400  1.96700   13.34800  1.000 63.92663  ?  238 THR A CB     1 
ATOM   1194 O  OG1    . THR A 1 74 ? 21.54700  1.31700   12.25500  1.000 71.17234  ?  238 THR A OG1    1 
ATOM   1195 C  CG2    . THR A 1 74 ? 22.75400  0.93800   14.30000  1.000 73.98742  ?  238 THR A CG2    1 
ATOM   1196 H  H      . THR A 1 74 ? 21.09700  3.85500   12.29600  1.000 70.92201  ?  238 THR A H      1 
ATOM   1197 H  HA     . THR A 1 74 ? 20.46900  2.32000   14.38600  1.000 69.27914  ?  238 THR A HA     1 
ATOM   1198 H  HB     . THR A 1 74 ? 22.92400  2.50400   13.00700  1.000 76.71195  ?  238 THR A HB     1 
ATOM   1199 H  HG1    . THR A 1 74 ? 22.08700  0.80600   11.86400  1.000 85.40681  ?  238 THR A HG1    1 
ATOM   1200 H  HG21   . THR A 1 74 ? 23.36900  0.35300   13.83000  1.000 88.78490  ?  238 THR A HG21   1 
ATOM   1201 H  HG22   . THR A 1 74 ? 23.22800  1.37800   15.02300  1.000 88.78490  ?  238 THR A HG22   1 
ATOM   1202 H  HG23   . THR A 1 74 ? 22.03400  0.40500   14.67200  1.000 88.78490  ?  238 THR A HG23   1 
ATOM   1203 N  N      . GLY A 1 75 ? 22.62300  4.67300   14.88400  1.000 51.33030  ?  239 GLY A N      1 
ATOM   1204 C  CA     . GLY A 1 75 ? 23.12100  5.62000   15.89800  1.000 52.16734  ?  239 GLY A CA     1 
ATOM   1205 C  C      . GLY A 1 75 ? 24.62200  5.82300   15.89300  1.000 48.16493  ?  239 GLY A C      1 
ATOM   1206 O  O      . GLY A 1 75 ? 25.05900  6.72300   16.60600  1.000 46.04783  ?  239 GLY A O      1 
ATOM   1207 H  H      . GLY A 1 75 ? 22.96300  4.79600   14.10400  1.000 61.59636  ?  239 GLY A H      1 
ATOM   1208 H  HA2    . GLY A 1 75 ? 22.70200  6.48300   15.75500  1.000 62.60081  ?  239 GLY A HA2    1 
ATOM   1209 H  HA3    . GLY A 1 75 ? 22.86600  5.30500   16.77900  1.000 62.60081  ?  239 GLY A HA3    1 
ATOM   1210 N  N      . GLU A 1 76 ? 25.38800  5.06000   15.11800  1.000 46.63000  ?  240 GLU A N      1 
ATOM   1211 C  CA     . GLU A 1 76 ? 26.83900  5.16200   15.16600  1.000 45.08132  ?  240 GLU A CA     1 
ATOM   1212 C  C      . GLU A 1 76 ? 27.32600  6.56900   14.79800  1.000 45.04099  ?  240 GLU A C      1 
ATOM   1213 O  O      . GLU A 1 76 ? 28.35400  7.04600   15.30500  1.000 42.08511  ?  240 GLU A O      1 
ATOM   1214 C  CB     . GLU A 1 76 ? 27.47800  4.13200   14.22700  1.000 43.78011  ?  240 GLU A CB     1 
ATOM   1215 C  CG     . GLU A 1 76 ? 27.24000  2.70500   14.62300  1.000 52.34868  ?  240 GLU A CG     1 
ATOM   1216 C  CD     . GLU A 1 76 ? 25.93100  2.17100   14.08300  1.000 60.76996  ?  240 GLU A CD     1 
ATOM   1217 O  OE1    . GLU A 1 76 ? 25.07700  3.00600   13.65700  1.000 60.84842  ?  240 GLU A OE1    1 
ATOM   1218 O  OE2    . GLU A 1 76 ? 25.77000  0.91800   14.08100  1.000 67.58081  -1 240 GLU A OE2    1 
ATOM   1219 H  H      . GLU A 1 76 ? 25.09000  4.48200   14.55600  1.000 55.95600  ?  240 GLU A H      1 
ATOM   1220 H  HA     . GLU A 1 76 ? 27.13800  4.96900   16.06800  1.000 54.09758  ?  240 GLU A HA     1 
ATOM   1221 H  HB2    . GLU A 1 76 ? 27.11800  4.25700   13.33500  1.000 52.53613  ?  240 GLU A HB2    1 
ATOM   1222 H  HB3    . GLU A 1 76 ? 28.43700  4.27700   14.21400  1.000 52.53613  ?  240 GLU A HB3    1 
ATOM   1223 H  HG2    . GLU A 1 76 ? 27.95800  2.15400   14.27300  1.000 62.81841  ?  240 GLU A HG2    1 
ATOM   1224 H  HG3    . GLU A 1 76 ? 27.21400  2.64400   15.59100  1.000 62.81841  ?  240 GLU A HG3    1 
ATOM   1225 N  N      . VAL A 1 77 ? 26.64900  7.23500   13.88600  1.000 39.60699  ?  241 VAL A N      1 
ATOM   1226 C  CA     . VAL A 1 77 ? 27.13500  8.51300   13.40800  1.000 41.47722  ?  241 VAL A CA     1 
ATOM   1227 C  C      . VAL A 1 77 ? 25.91900  9.37300   13.18000  1.000 40.21824  ?  241 VAL A C      1 
ATOM   1228 O  O      . VAL A 1 77 ? 24.99300  8.98000   12.46200  1.000 41.60778  ?  241 VAL A O      1 
ATOM   1229 C  CB     . VAL A 1 77 ? 27.95400  8.40700   12.10500  1.000 43.85858  ?  241 VAL A CB     1 
ATOM   1230 C  CG1    . VAL A 1 77 ? 28.53300  9.76900   11.73300  1.000 40.55294  ?  241 VAL A CG1    1 
ATOM   1231 C  CG2    . VAL A 1 77 ? 29.07700  7.42200   12.23900  1.000 39.46288  ?  241 VAL A CG2    1 
ATOM   1232 H  H      . VAL A 1 77 ? 25.91200  6.97400   13.52900  1.000 47.52838  ?  241 VAL A H      1 
ATOM   1233 H  HA     . VAL A 1 77 ? 27.68500  8.93500   14.08600  1.000 49.77266  ?  241 VAL A HA     1 
ATOM   1234 H  HB     . VAL A 1 77 ? 27.37500  8.11400   11.38400  1.000 52.63030  ?  241 VAL A HB     1 
ATOM   1235 H  HG11   . VAL A 1 77 ? 29.13200  9.66100   10.97800  1.000 48.66353  ?  241 VAL A HG11   1 
ATOM   1236 H  HG12   . VAL A 1 77 ? 27.80900  10.36900  11.49500  1.000 48.66353  ?  241 VAL A HG12   1 
ATOM   1237 H  HG13   . VAL A 1 77 ? 29.02100  10.12200  12.49300  1.000 48.66353  ?  241 VAL A HG13   1 
ATOM   1238 H  HG21   . VAL A 1 77 ? 29.60800  7.43600   11.42700  1.000 47.35546  ?  241 VAL A HG21   1 
ATOM   1239 H  HG22   . VAL A 1 77 ? 29.62600  7.67200   12.99800  1.000 47.35546  ?  241 VAL A HG22   1 
ATOM   1240 H  HG23   . VAL A 1 77 ? 28.70600  6.53600   12.37600  1.000 47.35546  ?  241 VAL A HG23   1 
ATOM   1241 N  N      . LYS A 1 78 ? 25.93600  10.53900  13.78200  1.000 42.02063  ?  242 LYS A N      1 
ATOM   1242 C  CA     . LYS A 1 78 ? 24.83100  11.46900  13.78000  1.000 42.19082  ?  242 LYS A CA     1 
ATOM   1243 C  C      . LYS A 1 78 ? 25.29200  12.66500  12.97700  1.000 43.86469  ?  242 LYS A C      1 
ATOM   1244 O  O      . LYS A 1 78 ? 26.44600  13.07400  13.08400  1.000 39.66442  ?  242 LYS A O      1 
ATOM   1245 C  CB     . LYS A 1 78 ? 24.47300  11.91000  15.21200  1.000 44.64377  ?  242 LYS A CB     1 
ATOM   1246 C  CG     . LYS A 1 78 ? 24.00400  10.81300  16.20800  1.000 56.86815  ?  242 LYS A CG     1 
ATOM   1247 C  CD     . LYS A 1 78 ? 22.46900  10.69800  16.38000  1.000 65.41532  ?  242 LYS A CD     1 
ATOM   1248 C  CE     . LYS A 1 78 ? 21.82100  9.97400   15.14800  1.000 72.12611  ?  242 LYS A CE     1 
ATOM   1249 N  NZ     . LYS A 1 78 ? 20.32400  10.09100  14.94200  1.000 59.95107  ?  242 LYS A NZ     1 
ATOM   1250 H  H      . LYS A 1 78 ? 26.61500  10.83000  14.22300  1.000 50.42475  ?  242 LYS A H      1 
ATOM   1251 H  HA     . LYS A 1 78 ? 24.05400  11.07500  13.35400  1.000 50.62899  ?  242 LYS A HA     1 
ATOM   1252 H  HB2    . LYS A 1 78 ? 25.25700  12.32900  15.60100  1.000 53.57252  ?  242 LYS A HB2    1 
ATOM   1253 H  HB3    . LYS A 1 78 ? 23.75900  12.56400  15.15400  1.000 53.57252  ?  242 LYS A HB3    1 
ATOM   1254 H  HG2    . LYS A 1 78 ? 24.32800  9.95400   15.89600  1.000 68.24178  ?  242 LYS A HG2    1 
ATOM   1255 H  HG3    . LYS A 1 78 ? 24.38200  11.00600  17.08000  1.000 68.24178  ?  242 LYS A HG3    1 
ATOM   1256 H  HD2    . LYS A 1 78 ? 22.27200  10.18100  17.17700  1.000 78.49839  ?  242 LYS A HD2    1 
ATOM   1257 H  HD3    . LYS A 1 78 ? 22.08500  11.58600  16.45000  1.000 78.49839  ?  242 LYS A HD3    1 
ATOM   1258 H  HE2    . LYS A 1 78 ? 22.23900  10.32100  14.34600  1.000 86.55133  ?  242 LYS A HE2    1 
ATOM   1259 H  HE3    . LYS A 1 78 ? 22.02000  9.02800   15.22200  1.000 86.55133  ?  242 LYS A HE3    1 
ATOM   1260 H  HZ1    . LYS A 1 78 ? 20.07400  9.60100   14.24200  1.000 71.94129  ?  242 LYS A HZ1    1 
ATOM   1261 H  HZ2    . LYS A 1 78 ? 19.89600  9.80200   15.66600  1.000 71.94129  ?  242 LYS A HZ2    1 
ATOM   1262 H  HZ3    . LYS A 1 78 ? 20.10300  10.94000  14.79500  1.000 71.94129  ?  242 LYS A HZ3    1 
ATOM   1263 N  N      . LYS A 1 79 ? 24.40900  13.22400  12.17100  1.000 42.43440  ?  243 LYS A N      1 
ATOM   1264 C  CA     . LYS A 1 79 ? 24.74200  14.44200  11.46300  1.000 47.04548  ?  243 LYS A CA     1 
ATOM   1265 C  C      . LYS A 1 79 ? 24.61500  15.59700  12.44000  1.000 41.06907  ?  243 LYS A C      1 
ATOM   1266 O  O      . LYS A 1 79 ? 23.66500  15.65200  13.19600  1.000 50.42493  ?  243 LYS A O      1 
ATOM   1267 C  CB     . LYS A 1 79 ? 23.82000  14.63800  10.24200  1.000 42.37622  ?  243 LYS A CB     1 
ATOM   1268 C  CG     . LYS A 1 79 ? 24.24600  15.82000  9.35100   1.000 40.32409  ?  243 LYS A CG     1 
ATOM   1269 C  CD     . LYS A 1 79 ? 25.51100  15.50500  8.64800   1.000 46.32680  ?  243 LYS A CD     1 
ATOM   1270 C  CE     . LYS A 1 79 ? 25.90400  16.57200  7.62900   1.000 43.92949  ?  243 LYS A CE     1 
ATOM   1271 N  NZ     . LYS A 1 79 ? 26.19000  17.83800  8.38500   1.000 46.18673  ?  243 LYS A NZ     1 
ATOM   1272 H  H      . LYS A 1 79 ? 23.61800  12.92200  12.01800  1.000 50.92128  ?  243 LYS A H      1 
ATOM   1273 H  HA     . LYS A 1 79 ? 25.66100  14.39600  11.15700  1.000 56.45458  ?  243 LYS A HA     1 
ATOM   1274 H  HB2    . LYS A 1 79 ? 23.83800  13.83300  9.70100   1.000 50.85146  ?  243 LYS A HB2    1 
ATOM   1275 H  HB3    . LYS A 1 79 ? 22.91700  14.80800  10.55300  1.000 50.85146  ?  243 LYS A HB3    1 
ATOM   1276 H  HG2    . LYS A 1 79 ? 23.55900  15.98800  8.68700   1.000 48.38891  ?  243 LYS A HG2    1 
ATOM   1277 H  HG3    . LYS A 1 79 ? 24.38600  16.60700  9.90000   1.000 48.38891  ?  243 LYS A HG3    1 
ATOM   1278 H  HD2    . LYS A 1 79 ? 26.22900  15.43100  9.29500   1.000 55.59216  ?  243 LYS A HD2    1 
ATOM   1279 H  HD3    . LYS A 1 79 ? 25.40000  14.66800  8.17300   1.000 55.59216  ?  243 LYS A HD3    1 
ATOM   1280 H  HE2    . LYS A 1 79 ? 26.70500  16.30000  7.15400   1.000 52.71538  ?  243 LYS A HE2    1 
ATOM   1281 H  HE3    . LYS A 1 79 ? 25.17100  16.73000  7.01400   1.000 52.71538  ?  243 LYS A HE3    1 
ATOM   1282 H  HZ1    . LYS A 1 79 ? 26.46300  18.47200  7.82300   1.000 55.42407  ?  243 LYS A HZ1    1 
ATOM   1283 H  HZ2    . LYS A 1 79 ? 25.45400  18.11700  8.80100   1.000 55.42407  ?  243 LYS A HZ2    1 
ATOM   1284 H  HZ3    . LYS A 1 79 ? 26.82700  17.69400  8.98900   1.000 55.42407  ?  243 LYS A HZ3    1 
ATOM   1285 N  N      . VAL A 1 80 ? 25.55900  16.46200  12.45200  1.000 47.53484  ?  244 VAL A N      1 
ATOM   1286 C  CA     . VAL A 1 80 ? 25.44400  17.75200  13.12300  1.000 49.00650  ?  244 VAL A CA     1 
ATOM   1287 C  C      . VAL A 1 80 ? 24.94100  18.82000  12.16000  1.000 54.48433  ?  244 VAL A C      1 
ATOM   1288 O  O      . VAL A 1 80 ? 25.17300  18.76200  10.93600  1.000 55.92142  ?  244 VAL A O      1 
ATOM   1289 C  CB     . VAL A 1 80 ? 26.80400  18.15200  13.71500  1.000 45.13450  ?  244 VAL A CB     1 
ATOM   1290 C  CG1    . VAL A 1 80 ? 26.75800  19.58700  14.21600  1.000 53.23840  ?  244 VAL A CG1    1 
ATOM   1291 C  CG2    . VAL A 1 80 ? 27.17400  17.15200  14.81500  1.000 46.38567  ?  244 VAL A CG2    1 
ATOM   1292 H  H      . VAL A 1 80 ? 26.32000  16.34300  12.06900  1.000 57.04181  ?  244 VAL A H      1 
ATOM   1293 H  HA     . VAL A 1 80 ? 24.80800  17.67900  13.85200  1.000 58.80780  ?  244 VAL A HA     1 
ATOM   1294 H  HB     . VAL A 1 80 ? 27.47900  18.09800  13.02100  1.000 54.16140  ?  244 VAL A HB     1 
ATOM   1295 H  HG11   . VAL A 1 80 ? 27.54800  19.75600  14.75300  1.000 63.88608  ?  244 VAL A HG11   1 
ATOM   1296 H  HG12   . VAL A 1 80 ? 26.74000  20.19200  13.46100  1.000 63.88608  ?  244 VAL A HG12   1 
ATOM   1297 H  HG13   . VAL A 1 80 ? 25.96200  19.70600  14.75700  1.000 63.88608  ?  244 VAL A HG13   1 
ATOM   1298 H  HG21   . VAL A 1 80 ? 28.00800  17.43000  15.22600  1.000 55.66281  ?  244 VAL A HG21   1 
ATOM   1299 H  HG22   . VAL A 1 80 ? 26.46700  17.13700  15.47800  1.000 55.66281  ?  244 VAL A HG22   1 
ATOM   1300 H  HG23   . VAL A 1 80 ? 27.27700  16.27200  14.42100  1.000 55.66281  ?  244 VAL A HG23   1 
ATOM   1301 N  N      . LYS A 1 81 ? 24.28300  19.83800  12.71400  1.000 55.87220  ?  245 LYS A N      1 
ATOM   1302 C  CA     . LYS A 1 81 ? 23.68900  20.88600  11.88400  1.000 67.39338  ?  245 LYS A CA     1 
ATOM   1303 C  C      . LYS A 1 81 ? 24.73900  21.93700  11.54200  1.000 65.12012  ?  245 LYS A C      1 
ATOM   1304 O  O      . LYS A 1 81 ? 24.51700  23.14100  11.70600  1.000 66.46732  ?  245 LYS A O      1 
ATOM   1305 C  CB     . LYS A 1 81 ? 22.47700  21.53400  12.56500  1.000 63.96252  ?  245 LYS A CB     1 
ATOM   1306 C  CG     . LYS A 1 81 ? 21.38200  20.55600  12.99800  1.000 71.14492  ?  245 LYS A CG     1 
ATOM   1307 C  CD     . LYS A 1 81 ? 20.82300  19.75500  11.85100  1.000 80.53614  ?  245 LYS A CD     1 
ATOM   1308 C  CE     . LYS A 1 81 ? 20.37000  20.66400  10.71100  1.000 84.20708  ?  245 LYS A CE     1 
ATOM   1309 N  NZ     . LYS A 1 81 ? 19.44400  19.97200  9.76100   1.000 77.67848  ?  245 LYS A NZ     1 
ATOM   1310 H  H      . LYS A 1 81 ? 24.16700  19.94500  13.55900  1.000 67.04664  ?  245 LYS A H      1 
ATOM   1311 H  HA     . LYS A 1 81 ? 23.38500  20.49100  11.05200  1.000 80.87206  ?  245 LYS A HA     1 
ATOM   1312 H  HB2    . LYS A 1 81 ? 22.78600  21.99000  13.36300  1.000 76.75503  ?  245 LYS A HB2    1 
ATOM   1313 H  HB3    . LYS A 1 81 ? 22.08600  22.18100  11.95800  1.000 76.75503  ?  245 LYS A HB3    1 
ATOM   1314 H  HG2    . LYS A 1 81 ? 21.75200  19.93500  13.64500  1.000 85.37391  ?  245 LYS A HG2    1 
ATOM   1315 H  HG3    . LYS A 1 81 ? 20.65300  21.05600  13.39700  1.000 85.37391  ?  245 LYS A HG3    1 
ATOM   1316 H  HD2    . LYS A 1 81 ? 21.50800  19.15800  11.51200  1.000 96.64337  ?  245 LYS A HD2    1 
ATOM   1317 H  HD3    . LYS A 1 81 ? 20.05600  19.24700  12.15800  1.000 96.64337  ?  245 LYS A HD3    1 
ATOM   1318 H  HE2    . LYS A 1 81 ? 19.90400  21.43000  11.08200  1.000 101.04850 ?  245 LYS A HE2    1 
ATOM   1319 H  HE3    . LYS A 1 81 ? 21.14700  20.95700  10.21100  1.000 101.04850 ?  245 LYS A HE3    1 
ATOM   1320 H  HZ1    . LYS A 1 81 ? 19.20200  20.53000  9.11200   1.000 93.21418  ?  245 LYS A HZ1    1 
ATOM   1321 H  HZ2    . LYS A 1 81 ? 19.85000  19.26700  9.40000   1.000 93.21418  ?  245 LYS A HZ2    1 
ATOM   1322 H  HZ3    . LYS A 1 81 ? 18.71600  19.69600  10.19300  1.000 93.21418  ?  245 LYS A HZ3    1 
ATOM   1323 N  N      . LYS A 1 82 ? 25.90300  21.46200  11.08000  1.000 60.98174  ?  246 LYS A N      1 
ATOM   1324 C  CA     . LYS A 1 82 ? 27.05100  22.30100  10.67800  1.000 56.70148  ?  246 LYS A CA     1 
ATOM   1325 C  C      . LYS A 1 82 ? 27.53700  21.69300  9.36500   1.000 55.08994  ?  246 LYS A C      1 
ATOM   1326 O  O      . LYS A 1 82 ? 27.45000  20.46400  9.24500   1.000 49.26986  ?  246 LYS A O      1 
ATOM   1327 C  CB     . LYS A 1 82 ? 28.16300  22.25100  11.72400  1.000 61.50902  ?  246 LYS A CB     1 
ATOM   1328 C  CG     . LYS A 1 82 ? 28.44200  23.55200  12.46300  1.000 78.83232  ?  246 LYS A CG     1 
ATOM   1329 C  CD     . LYS A 1 82 ? 27.31800  24.03100  13.35300  1.000 79.71945  ?  246 LYS A CD     1 
ATOM   1330 C  CE     . LYS A 1 82 ? 27.00000  23.09000  14.49600  1.000 89.90614  ?  246 LYS A CE     1 
ATOM   1331 N  NZ     . LYS A 1 82 ? 25.56400  22.72900  14.53500  1.000 86.60928  ?  246 LYS A NZ     1 
ATOM   1332 H  H      . LYS A 1 82 ? 26.06200  20.62400  10.97900  1.000 73.17809  ?  246 LYS A H      1 
ATOM   1333 H  HA     . LYS A 1 82 ? 26.77400  23.21900  10.53300  1.000 68.04177  ?  246 LYS A HA     1 
ATOM   1334 H  HB2    . LYS A 1 82 ? 27.93800  21.57900  12.38200  1.000 73.81082  ?  246 LYS A HB2    1 
ATOM   1335 H  HB3    . LYS A 1 82 ? 28.98500  21.99600  11.27700  1.000 73.81082  ?  246 LYS A HB3    1 
ATOM   1336 H  HG2    . LYS A 1 82 ? 29.22500  23.42800  13.02100  1.000 94.59879  ?  246 LYS A HG2    1 
ATOM   1337 H  HG3    . LYS A 1 82 ? 28.61500  24.24800  11.80900  1.000 94.59879  ?  246 LYS A HG3    1 
ATOM   1338 H  HD2    . LYS A 1 82 ? 27.56500  24.88800  13.73500  1.000 95.66334  ?  246 LYS A HD2    1 
ATOM   1339 H  HD3    . LYS A 1 82 ? 26.51500  24.13000  12.81700  1.000 95.66334  ?  246 LYS A HD3    1 
ATOM   1340 H  HE2    . LYS A 1 82 ? 27.51700  22.27600  14.40100  1.000 107.88737 ?  246 LYS A HE2    1 
ATOM   1341 H  HE3    . LYS A 1 82 ? 27.22100  23.52600  15.33400  1.000 107.88737 ?  246 LYS A HE3    1 
ATOM   1342 H  HZ1    . LYS A 1 82 ? 25.34100  22.45700  15.35300  1.000 103.93113 ?  246 LYS A HZ1    1 
ATOM   1343 H  HZ2    . LYS A 1 82 ? 25.06700  23.43500  14.32000  1.000 103.93113 ?  246 LYS A HZ2    1 
ATOM   1344 H  HZ3    . LYS A 1 82 ? 25.40000  22.07300  13.95700  1.000 103.93113 ?  246 LYS A HZ3    1 
ATOM   1345 N  N      . LYS A 1 83 ? 27.99500  22.49800  8.41600   1.000 55.41127  ?  247 LYS A N      1 
ATOM   1346 C  CA     . LYS A 1 83 ? 28.47300  22.05200  7.11700   1.000 53.46533  ?  247 LYS A CA     1 
ATOM   1347 C  C      . LYS A 1 83 ? 29.55100  20.98500  7.29000   1.000 46.66501  ?  247 LYS A C      1 
ATOM   1348 O  O      . LYS A 1 83 ? 30.56600  21.22500  7.95100   1.000 46.50004  ?  247 LYS A O      1 
ATOM   1349 C  CB     . LYS A 1 83 ? 29.01800  23.27400  6.35800   1.000 54.75785  ?  247 LYS A CB     1 
ATOM   1350 C  CG     . LYS A 1 83 ? 28.79600  23.27000  4.84900   1.000 56.61165  ?  247 LYS A CG     1 
ATOM   1351 C  CD     . LYS A 1 83 ? 29.78300  24.19100  4.10200   1.000 57.67786  ?  247 LYS A CD     1 
ATOM   1352 C  CE     . LYS A 1 83 ? 30.15700  25.47300  4.85700   0.000 61.08379  ?  247 LYS A CE     1 
ATOM   1353 N  NZ     . LYS A 1 83 ? 29.02200  26.37400  5.21700   1.000 73.79597  ?  247 LYS A NZ     1 
ATOM   1354 H  H      . LYS A 1 83 ? 28.03900  23.35100  8.51200   1.000 66.49353  ?  247 LYS A H      1 
ATOM   1355 H  HA     . LYS A 1 83 ? 27.73800  21.67300  6.61000   1.000 64.15840  ?  247 LYS A HA     1 
ATOM   1356 H  HB2    . LYS A 1 83 ? 28.59700  24.07400  6.71000   1.000 65.70942  ?  247 LYS A HB2    1 
ATOM   1357 H  HB3    . LYS A 1 83 ? 29.97500  23.31600  6.51100   1.000 65.70942  ?  247 LYS A HB3    1 
ATOM   1358 H  HG2    . LYS A 1 83 ? 28.91500  22.36700  4.51400   1.000 67.93398  ?  247 LYS A HG2    1 
ATOM   1359 H  HG3    . LYS A 1 83 ? 27.89600  23.57900  4.66100   1.000 67.93398  ?  247 LYS A HG3    1 
ATOM   1360 H  HD2    . LYS A 1 83 ? 30.60200  23.69800  3.93600   1.000 69.21343  ?  247 LYS A HD2    1 
ATOM   1361 H  HD3    . LYS A 1 83 ? 29.38400  24.45300  3.25800   1.000 69.21343  ?  247 LYS A HD3    1 
ATOM   1362 H  HE2    . LYS A 1 83 ? 30.62000  25.23900  5.67600   0.000 73.30055  ?  247 LYS A HE2    1 
ATOM   1363 H  HE3    . LYS A 1 83 ? 30.75600  25.98600  4.29200   0.000 73.30055  ?  247 LYS A HE3    1 
ATOM   1364 H  HZ1    . LYS A 1 83 ? 28.82600  26.89800  4.52600   1.000 88.55516  ?  247 LYS A HZ1    1 
ATOM   1365 H  HZ2    . LYS A 1 83 ? 28.30400  25.89300  5.43000   1.000 88.55516  ?  247 LYS A HZ2    1 
ATOM   1366 H  HZ3    . LYS A 1 83 ? 29.24700  26.88500  5.91000   1.000 88.55516  ?  247 LYS A HZ3    1 
ATOM   1367 N  N      . LEU A 1 84 ? 29.31100  19.80500  6.70900   1.000 44.58729  ?  248 LEU A N      1 
ATOM   1368 C  CA     . LEU A 1 84 ? 30.29600  18.72100  6.59000   1.000 44.12050  ?  248 LEU A CA     1 
ATOM   1369 C  C      . LEU A 1 84 ? 30.72000  18.13700  7.95800   1.000 41.30039  ?  248 LEU A C      1 
ATOM   1370 O  O      . LEU A 1 84 ? 31.78000  17.50200  8.08700   1.000 39.54090  ?  248 LEU A O      1 
ATOM   1371 C  CB     . LEU A 1 84 ? 31.52700  19.21600  5.82000   1.000 42.10286  ?  248 LEU A CB     1 
ATOM   1372 C  CG     . LEU A 1 84 ? 31.24700  19.70200  4.38400   1.000 45.29256  ?  248 LEU A CG     1 
ATOM   1373 C  CD1    . LEU A 1 84 ? 32.44700  20.43000  3.74800   1.000 42.81245  ?  248 LEU A CD1    1 
ATOM   1374 C  CD2    . LEU A 1 84 ? 30.86800  18.50500  3.55000   1.000 39.82620  ?  248 LEU A CD2    1 
ATOM   1375 H  H      . LEU A 1 84 ? 28.55100  19.60100  6.36100   1.000 53.50475  ?  248 LEU A H      1 
ATOM   1376 H  HA     . LEU A 1 84 ? 29.89800  17.99900  6.07900   1.000 52.94460  ?  248 LEU A HA     1 
ATOM   1377 H  HB2    . LEU A 1 84 ? 31.92100  19.95600  6.30800   1.000 50.52343  ?  248 LEU A HB2    1 
ATOM   1378 H  HB3    . LEU A 1 84 ? 32.16700  18.48900  5.76300   1.000 50.52343  ?  248 LEU A HB3    1 
ATOM   1379 H  HG     . LEU A 1 84 ? 30.49400  20.31300  4.39500   1.000 54.35107  ?  248 LEU A HG     1 
ATOM   1380 H  HD11   . LEU A 1 84 ? 32.20700  20.71000  2.85100   1.000 51.37494  ?  248 LEU A HD11   1 
ATOM   1381 H  HD12   . LEU A 1 84 ? 32.66900  21.20400  4.28900   1.000 51.37494  ?  248 LEU A HD12   1 
ATOM   1382 H  HD13   . LEU A 1 84 ? 33.20200  19.82200  3.71400   1.000 51.37494  ?  248 LEU A HD13   1 
ATOM   1383 H  HD21   . LEU A 1 84 ? 30.82100  18.77300  2.61900   1.000 47.79143  ?  248 LEU A HD21   1 
ATOM   1384 H  HD22   . LEU A 1 84 ? 31.54200  17.81600  3.66200   1.000 47.79143  ?  248 LEU A HD22   1 
ATOM   1385 H  HD23   . LEU A 1 84 ? 30.00500  18.17500  3.84300   1.000 47.79143  ?  248 LEU A HD23   1 
ATOM   1386 N  N      . THR A 1 85 ? 29.91000  18.34100  8.96600   1.000 40.59044  ?  249 THR A N      1 
ATOM   1387 C  CA     . THR A 1 85 ? 30.20700  17.92500  10.33400  1.000 41.99382  ?  249 THR A CA     1 
ATOM   1388 C  C      . THR A 1 85 ? 29.29700  16.78500  10.79500  1.000 39.43144  ?  249 THR A C      1 
ATOM   1389 O  O      . THR A 1 85 ? 28.09200  16.80000  10.54600  1.000 38.83681  ?  249 THR A O      1 
ATOM   1390 C  CB     . THR A 1 85 ? 30.06100  19.12900  11.27000  1.000 44.73484  ?  249 THR A CB     1 
ATOM   1391 O  OG1    . THR A 1 85 ? 30.87100  20.21500  10.76000  1.000 45.31167  ?  249 THR A OG1    1 
ATOM   1392 C  CG2    . THR A 1 85 ? 30.49200  18.77200  12.64800  1.000 37.88622  ?  249 THR A CG2    1 
ATOM   1393 H  H      . THR A 1 85 ? 29.14800  18.73300  8.89100   1.000 48.70852  ?  249 THR A H      1 
ATOM   1394 H  HA     . THR A 1 85 ? 31.12500  17.61700  10.38200  1.000 50.39258  ?  249 THR A HA     1 
ATOM   1395 H  HB     . THR A 1 85 ? 29.13200  19.40500  11.30000  1.000 53.68181  ?  249 THR A HB     1 
ATOM   1396 H  HG1    . THR A 1 85 ? 31.67700  19.98100  10.72600  1.000 54.37401  ?  249 THR A HG1    1 
ATOM   1397 H  HG21   . THR A 1 85 ? 30.55900  19.57300  13.19000  1.000 45.46347  ?  249 THR A HG21   1 
ATOM   1398 H  HG22   . THR A 1 85 ? 29.84900  18.17100  13.05500  1.000 45.46347  ?  249 THR A HG22   1 
ATOM   1399 H  HG23   . THR A 1 85 ? 31.35900  18.33800  12.62200  1.000 45.46347  ?  249 THR A HG23   1 
ATOM   1400 N  N      . TYR A 1 86 ? 29.89900  15.78400  11.43600  1.000 37.94347  ?  250 TYR A N      1 
ATOM   1401 C  CA     . TYR A 1 86 ? 29.24000  14.60700  11.95800  1.000 36.10535  ?  250 TYR A CA     1 
ATOM   1402 C  C      . TYR A 1 86 ? 29.68600  14.31400  13.39600  1.000 37.56039  ?  250 TYR A C      1 
ATOM   1403 O  O      . TYR A 1 86 ? 30.62700  14.92100  13.91800  1.000 35.52027  ?  250 TYR A O      1 
ATOM   1404 C  CB     . TYR A 1 86 ? 29.56700  13.39400  11.10200  1.000 38.35530  ?  250 TYR A CB     1 
ATOM   1405 C  CG     . TYR A 1 86 ? 29.08100  13.53800  9.69700   1.000 39.47706  ?  250 TYR A CG     1 
ATOM   1406 C  CD1    . TYR A 1 86 ? 29.74900  14.35500  8.78600   1.000 39.11864  ?  250 TYR A CD1    1 
ATOM   1407 C  CD2    . TYR A 1 86 ? 27.95700  12.86500  9.28200   1.000 36.59162  ?  250 TYR A CD2    1 
ATOM   1408 C  CE1    . TYR A 1 86 ? 29.29000  14.49400  7.47700   1.000 37.61893  ?  250 TYR A CE1    1 
ATOM   1409 C  CE2    . TYR A 1 86 ? 27.49200  12.99500  7.98300   1.000 35.98153  ?  250 TYR A CE2    1 
ATOM   1410 C  CZ     . TYR A 1 86 ? 28.14500  13.80600  7.09300   1.000 39.45504  ?  250 TYR A CZ     1 
ATOM   1411 O  OH     . TYR A 1 86 ? 27.65500  13.90400  5.79500   1.000 40.98523  ?  250 TYR A OH     1 
ATOM   1412 H  H      . TYR A 1 86 ? 30.74600  15.77400  11.58500  1.000 45.53217  ?  250 TYR A H      1 
ATOM   1413 H  HA     . TYR A 1 86 ? 28.27900  14.74100  11.95200  1.000 43.32642  ?  250 TYR A HA     1 
ATOM   1414 H  HB2    . TYR A 1 86 ? 30.52900  13.28100  11.07500  1.000 46.02636  ?  250 TYR A HB2    1 
ATOM   1415 H  HB3    . TYR A 1 86 ? 29.14800  12.60800  11.48700  1.000 46.02636  ?  250 TYR A HB3    1 
ATOM   1416 H  HD1    . TYR A 1 86 ? 30.50900  14.81700  9.05700   1.000 46.94237  ?  250 TYR A HD1    1 
ATOM   1417 H  HD2    . TYR A 1 86 ? 27.50100  12.31800  9.88100   1.000 43.90994  ?  250 TYR A HD2    1 
ATOM   1418 H  HE1    . TYR A 1 86 ? 29.73900  15.04100  6.87300   1.000 45.14272  ?  250 TYR A HE1    1 
ATOM   1419 H  HE2    . TYR A 1 86 ? 26.72900  12.53500  7.71600   1.000 43.17783  ?  250 TYR A HE2    1 
ATOM   1420 H  HH     . TYR A 1 86 ? 28.14500  14.41300  5.34100   1.000 49.18228  ?  250 TYR A HH     1 
ATOM   1421 N  N      . GLN A 1 87 ? 29.10500  13.27100  13.99100  1.000 34.45176  ?  251 GLN A N      1 
ATOM   1422 C  CA     . GLN A 1 87 ? 29.41900  12.98000  15.39100  1.000 37.66028  ?  251 GLN A CA     1 
ATOM   1423 C  C      . GLN A 1 87 ? 29.27300  11.50100  15.69300  1.000 32.00846  ?  251 GLN A C      1 
ATOM   1424 O  O      . GLN A 1 87 ? 28.17700  10.95800  15.58000  1.000 35.81323  ?  251 GLN A O      1 
ATOM   1425 C  CB     . GLN A 1 87 ? 28.49300  13.78600  16.31000  1.000 39.76862  ?  251 GLN A CB     1 
ATOM   1426 C  CG     . GLN A 1 87 ? 28.83600  13.61500  17.79800  1.000 45.76166  ?  251 GLN A CG     1 
ATOM   1427 C  CD     . GLN A 1 87 ? 27.97500  14.48400  18.75400  1.000 50.42532  ?  251 GLN A CD     1 
ATOM   1428 O  OE1    . GLN A 1 87 ? 26.85500  14.87100  18.44100  1.000 52.35836  ?  251 GLN A OE1    1 
ATOM   1429 N  NE2    . GLN A 1 87 ? 28.50400  14.74300  19.93400  1.000 54.29533  ?  251 GLN A NE2    1 
ATOM   1430 H  H      . GLN A 1 87 ? 28.54500  12.73300  13.62200  1.000 41.34212  ?  251 GLN A H      1 
ATOM   1431 H  HA     . GLN A 1 87 ? 30.33500  13.23700  15.57900  1.000 45.19234  ?  251 GLN A HA     1 
ATOM   1432 H  HB2    . GLN A 1 87 ? 28.57100  14.72800  16.09000  1.000 47.72234  ?  251 GLN A HB2    1 
ATOM   1433 H  HB3    . GLN A 1 87 ? 27.57900  13.48900  16.17700  1.000 47.72234  ?  251 GLN A HB3    1 
ATOM   1434 H  HG2    . GLN A 1 87 ? 28.70100  12.68700  18.04600  1.000 54.91399  ?  251 GLN A HG2    1 
ATOM   1435 H  HG3    . GLN A 1 87 ? 29.76500  13.85900  17.93300  1.000 54.91399  ?  251 GLN A HG3    1 
ATOM   1436 H  HE21   . GLN A 1 87 ? 29.29000  14.45100  20.12600  1.000 65.15440  ?  251 GLN A HE21   1 
ATOM   1437 H  HE22   . GLN A 1 87 ? 28.07000  15.21700  20.50500  1.000 65.15440  ?  251 GLN A HE22   1 
ATOM   1438 N  N      . PHE A 1 88 ? 30.36300  10.86400  16.10500  1.000 33.90979  ?  252 PHE A N      1 
ATOM   1439 C  CA     . PHE A 1 88 ? 30.32200  9.47100   16.53800  1.000 38.11477  ?  252 PHE A CA     1 
ATOM   1440 C  C      . PHE A 1 88 ? 29.52800  9.32400   17.84200  1.000 36.10831  ?  252 PHE A C      1 
ATOM   1441 O  O      . PHE A 1 88 ? 29.51400  10.22200  18.67400  1.000 37.39173  ?  252 PHE A O      1 
ATOM   1442 C  CB     . PHE A 1 88 ? 31.73500  8.93200   16.78800  1.000 38.68977  ?  252 PHE A CB     1 
ATOM   1443 C  CG     . PHE A 1 88 ? 32.58000  8.81800   15.56700  1.000 36.71566  ?  252 PHE A CG     1 
ATOM   1444 C  CD1    . PHE A 1 88 ? 32.37000  7.78700   14.65000  1.000 42.47675  ?  252 PHE A CD1    1 
ATOM   1445 C  CD2    . PHE A 1 88 ? 33.62100  9.70500   15.35600  1.000 36.18564  ?  252 PHE A CD2    1 
ATOM   1446 C  CE1    . PHE A 1 88 ? 33.19300  7.66900   13.50700  1.000 42.46874  ?  252 PHE A CE1    1 
ATOM   1447 C  CE2    . PHE A 1 88 ? 34.42500  9.59600   14.22900  1.000 37.86799  ?  252 PHE A CE2    1 
ATOM   1448 C  CZ     . PHE A 1 88 ? 34.20900  8.57200   13.30600  1.000 37.40445  ?  252 PHE A CZ     1 
ATOM   1449 H  H      . PHE A 1 88 ? 31.14500  11.21900  16.14400  1.000 40.69175  ?  252 PHE A H      1 
ATOM   1450 H  HA     . PHE A 1 88 ? 29.89900  8.92900   15.85400  1.000 45.73772  ?  252 PHE A HA     1 
ATOM   1451 H  HB2    . PHE A 1 88 ? 32.18900  9.52700   17.40500  1.000 46.42772  ?  252 PHE A HB2    1 
ATOM   1452 H  HB3    . PHE A 1 88 ? 31.66400  8.04800   17.18000  1.000 46.42772  ?  252 PHE A HB3    1 
ATOM   1453 H  HD1    . PHE A 1 88 ? 31.68100  7.17800   14.78800  1.000 50.97210  ?  252 PHE A HD1    1 
ATOM   1454 H  HD2    . PHE A 1 88 ? 33.77200  10.39200  15.96500  1.000 43.42277  ?  252 PHE A HD2    1 
ATOM   1455 H  HE1    . PHE A 1 88 ? 33.04400  6.98800   12.89100  1.000 50.96249  ?  252 PHE A HE1    1 
ATOM   1456 H  HE2    . PHE A 1 88 ? 35.11600  10.20400  14.09300  1.000 45.44159  ?  252 PHE A HE2    1 
ATOM   1457 H  HZ     . PHE A 1 88 ? 34.75200  8.50200   12.55400  1.000 44.88533  ?  252 PHE A HZ     1 
ATOM   1458 N  N      . SER A 1 89 ? 28.85600  8.18900   18.01000  1.000 34.89461  ?  253 SER A N      1 
ATOM   1459 C  CA     . SER A 1 89 ? 28.23500  7.89400   19.29200  1.000 42.12051  ?  253 SER A CA     1 
ATOM   1460 C  C      . SER A 1 89 ? 29.31000  7.55800   20.33300  1.000 48.69217  ?  253 SER A C      1 
ATOM   1461 O  O      . SER A 1 89 ? 30.45000  7.21400   19.99400  1.000 48.68275  ?  253 SER A O      1 
ATOM   1462 C  CB     . SER A 1 89 ? 27.28000  6.72200   19.14800  1.000 41.68364  ?  253 SER A CB     1 
ATOM   1463 O  OG     . SER A 1 89 ? 28.01300  5.51700   19.00400  1.000 47.57568  ?  253 SER A OG     1 
ATOM   1464 H  H      . SER A 1 89 ? 28.74700  7.58400   17.40800  1.000 41.87354  ?  253 SER A H      1 
ATOM   1465 H  HA     . SER A 1 89 ? 27.73500  8.66700   19.59900  1.000 50.54462  ?  253 SER A HA     1 
ATOM   1466 H  HB2    . SER A 1 89 ? 26.72400  6.66400   19.94100  1.000 50.02037  ?  253 SER A HB2    1 
ATOM   1467 H  HB3    . SER A 1 89 ? 26.72900  6.85600   18.36200  1.000 50.02037  ?  253 SER A HB3    1 
ATOM   1468 H  HG     . SER A 1 89 ? 27.48600  4.86700   18.93500  1.000 57.09082  ?  253 SER A HG     1 
ATOM   1469 N  N      . GLY A 1 90 ? 28.93600  7.68100   21.61600  1.000 51.09682  ?  254 GLY A N      1 
ATOM   1470 C  CA     . GLY A 1 90 ? 29.81500  7.22200   22.69300  1.000 51.04264  ?  254 GLY A CA     1 
ATOM   1471 C  C      . GLY A 1 90 ? 30.13500  5.74300   22.60800  1.000 50.31196  ?  254 GLY A C      1 
ATOM   1472 O  O      . GLY A 1 90 ? 31.27000  5.33100   22.85400  1.000 57.74050  ?  254 GLY A O      1 
ATOM   1473 H  H      . GLY A 1 90 ? 28.19200  8.02100   21.88100  1.000 61.31618  ?  254 GLY A H      1 
ATOM   1474 H  HA2    . GLY A 1 90 ? 30.64900  7.71700   22.66000  1.000 61.25117  ?  254 GLY A HA2    1 
ATOM   1475 H  HA3    . GLY A 1 90 ? 29.39100  7.39400   23.54800  1.000 61.25117  ?  254 GLY A HA3    1 
ATOM   1476 N  N      . GLU A 1 91 ? 29.13600  4.92800   22.24900  1.000 51.43278  ?  255 GLU A N      1 
ATOM   1477 C  CA     . GLU A 1 91 ? 29.35000  3.49900   22.01700  1.000 53.77316  ?  255 GLU A CA     1 
ATOM   1478 C  C      . GLU A 1 91 ? 30.44800  3.24500   20.98400  1.000 60.16366  ?  255 GLU A C      1 
ATOM   1479 O  O      . GLU A 1 91 ? 31.23500  2.29900   21.11700  1.000 63.74603  ?  255 GLU A O      1 
ATOM   1480 C  CB     . GLU A 1 91 ? 28.01800  2.87200   21.58400  1.000 62.13645  ?  255 GLU A CB     1 
ATOM   1481 C  CG     . GLU A 1 91 ? 27.92600  1.34700   21.62400  1.000 66.21713  ?  255 GLU A CG     1 
ATOM   1482 C  CD     . GLU A 1 91 ? 26.51400  0.82100   21.30400  1.000 87.39744  ?  255 GLU A CD     1 
ATOM   1483 O  OE1    . GLU A 1 91 ? 25.52600  1.27500   21.93800  1.000 85.48171  ?  255 GLU A OE1    1 
ATOM   1484 O  OE2    . GLU A 1 91 ? 26.39400  -0.05600  20.41100  1.000 91.68363  -1 255 GLU A OE2    1 
ATOM   1485 H  H      . GLU A 1 91 ? 28.32300  5.18200   22.13300  1.000 61.71934  ?  255 GLU A H      1 
ATOM   1486 H  HA     . GLU A 1 91 ? 29.62100  3.08200   22.85000  1.000 64.52780  ?  255 GLU A HA     1 
ATOM   1487 H  HB2    . GLU A 1 91 ? 27.32000  3.21600   22.16300  1.000 74.56374  ?  255 GLU A HB2    1 
ATOM   1488 H  HB3    . GLU A 1 91 ? 27.83800  3.14500   20.67100  1.000 74.56374  ?  255 GLU A HB3    1 
ATOM   1489 H  HG2    . GLU A 1 91 ? 28.53900  0.97700   20.96900  1.000 79.46056  ?  255 GLU A HG2    1 
ATOM   1490 H  HG3    . GLU A 1 91 ? 28.16500  1.04000   22.51200  1.000 79.46056  ?  255 GLU A HG3    1 
ATOM   1491 N  N      . VAL A 1 92 ? 30.53000  4.08400   19.94700  1.000 62.97184  ?  256 VAL A N      1 
ATOM   1492 C  CA     . VAL A 1 92 ? 31.49600  3.86400   18.87100  1.000 51.81206  ?  256 VAL A CA     1 
ATOM   1493 C  C      . VAL A 1 92 ? 32.89500  4.23300   19.31900  1.000 55.90164  ?  256 VAL A C      1 
ATOM   1494 O  O      . VAL A 1 92 ? 33.87600  3.58000   18.93400  1.000 55.62422  ?  256 VAL A O      1 
ATOM   1495 C  CB     . VAL A 1 92 ? 31.07700  4.67700   17.64300  1.000 50.29511  ?  256 VAL A CB     1 
ATOM   1496 C  CG1    . VAL A 1 92 ? 32.28500  4.93000   16.73500  1.000 53.50724  ?  256 VAL A CG1    1 
ATOM   1497 C  CG2    . VAL A 1 92 ? 29.94900  3.96700   16.90400  1.000 49.41979  ?  256 VAL A CG2    1 
ATOM   1498 H  H      . VAL A 1 92 ? 30.04000  4.78300   19.84500  1.000 75.56621  ?  256 VAL A H      1 
ATOM   1499 H  HA     . VAL A 1 92 ? 31.49400  2.92500   18.62800  1.000 62.17447  ?  256 VAL A HA     1 
ATOM   1500 H  HB     . VAL A 1 92 ? 30.74200  5.53800   17.93700  1.000 60.35413  ?  256 VAL A HB     1 
ATOM   1501 H  HG11   . VAL A 1 92 ? 31.96300  5.19300   15.85900  1.000 64.20869  ?  256 VAL A HG11   1 
ATOM   1502 H  HG12   . VAL A 1 92 ? 32.82700  5.64200   17.11000  1.000 64.20869  ?  256 VAL A HG12   1 
ATOM   1503 H  HG13   . VAL A 1 92 ? 32.80500  4.11400   16.65900  1.000 64.20869  ?  256 VAL A HG13   1 
ATOM   1504 H  HG21   . VAL A 1 92 ? 29.67800  4.51000   16.14700  1.000 59.30375  ?  256 VAL A HG21   1 
ATOM   1505 H  HG22   . VAL A 1 92 ? 30.26700  3.10400   16.59600  1.000 59.30375  ?  256 VAL A HG22   1 
ATOM   1506 H  HG23   . VAL A 1 92 ? 29.20100  3.84700   17.51000  1.000 59.30375  ?  256 VAL A HG23   1 
ATOM   1507 N  N      . LEU A 1 93 ? 33.00800  5.29400   20.12200  1.000 51.59686  ?  257 LEU A N      1 
ATOM   1508 C  CA     . LEU A 1 93 ? 34.29500  5.77000   20.62800  1.000 57.86859  ?  257 LEU A CA     1 
ATOM   1509 C  C      . LEU A 1 93 ? 34.94900  4.85900   21.68200  1.000 61.71965  ?  257 LEU A C      1 
ATOM   1510 O  O      . LEU A 1 93 ? 36.09700  5.12300   22.02300  1.000 68.41242  ?  257 LEU A O      1 
ATOM   1511 C  CB     . LEU A 1 93 ? 34.14100  7.17300   21.21800  1.000 50.28208  ?  257 LEU A CB     1 
ATOM   1512 C  CG     . LEU A 1 93 ? 33.65600  8.26400   20.27000  1.000 53.99593  ?  257 LEU A CG     1 
ATOM   1513 C  CD1    . LEU A 1 93 ? 33.19900  9.51700   21.02000  1.000 46.42919  ?  257 LEU A CD1    1 
ATOM   1514 C  CD2    . LEU A 1 93 ? 34.75200  8.58700   19.28600  1.000 47.24406  ?  257 LEU A CD2    1 
ATOM   1515 H  H      . LEU A 1 93 ? 32.33900  5.76300   20.39200  1.000 61.91623  ?  257 LEU A H      1 
ATOM   1516 H  HA     . LEU A 1 93 ? 34.91100  5.83400   19.88100  1.000 69.44230  ?  257 LEU A HA     1 
ATOM   1517 H  HB2    . LEU A 1 93 ? 33.50500  7.12600   21.94900  1.000 60.33850  ?  257 LEU A HB2    1 
ATOM   1518 H  HB3    . LEU A 1 93 ? 35.00400  7.45300   21.56200  1.000 60.33850  ?  257 LEU A HB3    1 
ATOM   1519 H  HG     . LEU A 1 93 ? 32.89800  7.92700   19.76800  1.000 64.79512  ?  257 LEU A HG     1 
ATOM   1520 H  HD11   . LEU A 1 93 ? 32.88300  10.17100  20.37800  1.000 55.71503  ?  257 LEU A HD11   1 
ATOM   1521 H  HD12   . LEU A 1 93 ? 32.48200  9.27700   21.62800  1.000 55.71503  ?  257 LEU A HD12   1 
ATOM   1522 H  HD13   . LEU A 1 93 ? 33.94900  9.87700   21.51800  1.000 55.71503  ?  257 LEU A HD13   1 
ATOM   1523 H  HD21   . LEU A 1 93 ? 34.46400  9.32300   18.72400  1.000 56.69287  ?  257 LEU A HD21   1 
ATOM   1524 H  HD22   . LEU A 1 93 ? 35.55200  8.83700   19.77500  1.000 56.69287  ?  257 LEU A HD22   1 
ATOM   1525 H  HD23   . LEU A 1 93 ? 34.92900  7.80500   18.74100  1.000 56.69287  ?  257 LEU A HD23   1 
ATOM   1526 N  N      . GLY A 1 94 ? 34.29400  3.79400   22.16800  1.000 63.70317  ?  258 GLY A N      1 
ATOM   1527 C  CA     . GLY A 1 94 ? 34.89700  2.86700   23.12200  1.000 74.27788  ?  258 GLY A CA     1 
ATOM   1528 C  C      . GLY A 1 94 ? 35.73900  1.75600   22.49600  1.000 86.41040  ?  258 GLY A C      1 
ATOM   1529 O  O      . GLY A 1 94 ? 36.92600  1.60600   22.81900  1.000 87.95616  ?  258 GLY A O      1 
ATOM   1530 H  H      . GLY A 1 94 ? 33.48700  3.58900   21.95300  1.000 76.44380  ?  258 GLY A H      1 
ATOM   1531 H  HA2    . GLY A 1 94 ? 35.46500  3.36600   23.73000  1.000 89.13345  ?  258 GLY A HA2    1 
ATOM   1532 H  HA3    . GLY A 1 94 ? 34.19300  2.45000   23.64300  1.000 89.13345  ?  258 GLY A HA3    1 
ATOM   1533 N  N      . ARG A 1 95 ? 35.13500  0.97500   21.59300  1.000 92.05105  ?  259 ARG A N      1 
ATOM   1534 C  CA     . ARG A 1 95 ? 35.78600  -0.19600  20.97700  1.000 91.31452  ?  259 ARG A CA     1 
ATOM   1535 C  C      . ARG A 1 95 ? 36.80100  0.14600   19.87500  1.000 86.63477  ?  259 ARG A C      1 
ATOM   1536 O  O      . ARG A 1 95 ? 36.43100  0.39400   18.72000  1.000 86.04789  ?  259 ARG A O      1 
ATOM   1537 C  CB     . ARG A 1 95 ? 34.71700  -1.13100  20.38800  1.000 87.15578  ?  259 ARG A CB     1 
ATOM   1538 H  H      . ARG A 1 95 ? 34.33200  1.10400   21.31400  1.000 110.46126 ?  259 ARG A H      1 
ATOM   1539 H  HA     . ARG A 1 95 ? 36.25800  -0.68600  21.66800  1.000 109.57742 ?  259 ARG A HA     1 
ATOM   1540 O  "O5'"  . DA  B 2 1  ? 18.89200  32.54100  -7.78400  1.000 95.67544  ?  1   DA  B "O5'"  1 
ATOM   1541 C  "C5'"  . DA  B 2 1  ? 18.32200  33.53400  -8.66900  1.000 91.41288  ?  1   DA  B "C5'"  1 
ATOM   1542 C  "C4'"  . DA  B 2 1  ? 19.37500  34.53800  -9.07300  1.000 92.01111  ?  1   DA  B "C4'"  1 
ATOM   1543 O  "O4'"  . DA  B 2 1  ? 19.56300  35.48000  -8.00200  1.000 83.38828  ?  1   DA  B "O4'"  1 
ATOM   1544 C  "C3'"  . DA  B 2 1  ? 20.75000  33.96000  -9.39000  1.000 95.30428  ?  1   DA  B "C3'"  1 
ATOM   1545 O  "O3'"  . DA  B 2 1  ? 21.28600  34.62900  -10.52400 1.000 95.39620  ?  1   DA  B "O3'"  1 
ATOM   1546 C  "C2'"  . DA  B 2 1  ? 21.60100  34.25100  -8.15600  1.000 88.67599  ?  1   DA  B "C2'"  1 
ATOM   1547 C  "C1'"  . DA  B 2 1  ? 20.77100  35.19700  -7.30500  1.000 83.53131  ?  1   DA  B "C1'"  1 
ATOM   1548 N  N9     . DA  B 2 1  ? 20.43000  34.67300  -5.98200  1.000 78.09048  ?  1   DA  B N9     1 
ATOM   1549 C  C8     . DA  B 2 1  ? 19.19500  34.44700  -5.42700  1.000 78.50215  ?  1   DA  B C8     1 
ATOM   1550 N  N7     . DA  B 2 1  ? 19.24900  34.01500  -4.19400  1.000 74.00697  ?  1   DA  B N7     1 
ATOM   1551 C  C5     . DA  B 2 1  ? 20.60300  33.96700  -3.90900  1.000 71.15386  ?  1   DA  B C5     1 
ATOM   1552 C  C6     . DA  B 2 1  ? 21.31000  33.59800  -2.75300  1.000 71.79641  ?  1   DA  B C6     1 
ATOM   1553 N  N6     . DA  B 2 1  ? 20.72600  33.17000  -1.64000  1.000 75.27457  ?  1   DA  B N6     1 
ATOM   1554 N  N1     . DA  B 2 1  ? 22.65900  33.65900  -2.79900  1.000 72.77437  ?  1   DA  B N1     1 
ATOM   1555 C  C2     . DA  B 2 1  ? 23.23800  34.07300  -3.93000  1.000 72.77931  ?  1   DA  B C2     1 
ATOM   1556 N  N3     . DA  B 2 1  ? 22.67800  34.44900  -5.07400  1.000 72.92690  ?  1   DA  B N3     1 
ATOM   1557 C  C4     . DA  B 2 1  ? 21.34200  34.37100  -4.99900  1.000 71.47349  ?  1   DA  B C4     1 
ATOM   1558 H  "H5'"  . DA  B 2 1  ? 17.59900  33.99300  -8.21300  1.000 109.69546 ?  1   DA  B "H5'"  1 
ATOM   1559 H  "H5''" . DA  B 2 1  ? 17.97500  33.09600  -9.46200  1.000 109.69546 ?  1   DA  B "H5''" 1 
ATOM   1560 H  "H4'"  . DA  B 2 1  ? 19.05700  35.01900  -9.85300  1.000 110.41334 ?  1   DA  B "H4'"  1 
ATOM   1561 H  "H3'"  . DA  B 2 1  ? 20.69200  33.00500  -9.54900  1.000 114.36514 ?  1   DA  B "H3'"  1 
ATOM   1562 H  "H2'"  . DA  B 2 1  ? 21.78100  33.43800  -7.67200  1.000 106.41118 ?  1   DA  B "H2'"  1 
ATOM   1563 H  "H2''" . DA  B 2 1  ? 22.43200  34.67800  -8.41600  1.000 106.41118 ?  1   DA  B "H2''" 1 
ATOM   1564 H  "H1'"  . DA  B 2 1  ? 21.26400  36.02400  -7.19200  1.000 100.23757 ?  1   DA  B "H1'"  1 
ATOM   1565 H  H8     . DA  B 2 1  ? 18.39700  34.58100  -5.88600  1.000 94.20258  ?  1   DA  B H8     1 
ATOM   1566 H  H61    . DA  B 2 1  ? 21.19600  32.79700  -1.02400  1.000 90.32948  ?  1   DA  B H61    1 
ATOM   1567 H  H62    . DA  B 2 1  ? 19.87700  33.26400  -1.53600  1.000 90.32948  ?  1   DA  B H62    1 
ATOM   1568 H  H2     . DA  B 2 1  ? 24.16700  34.10500  -3.91300  1.000 87.33517  ?  1   DA  B H2     1 
ATOM   1569 H  "HO5'" . DA  B 2 1  ? 19.61800  32.69400  -7.39100  1.000 114.81053 ?  1   DA  B "HO5'" 1 
ATOM   1570 P  P      . DA  B 2 2  ? 22.38400  33.92200  -11.45500 1.000 101.88464 ?  2   DA  B P      1 
ATOM   1571 O  OP1    . DA  B 2 2  ? 23.42700  34.89600  -11.95000 1.000 110.87230 -1 2   DA  B OP1    1 
ATOM   1572 O  OP2    . DA  B 2 2  ? 21.74800  33.09500  -12.54700 1.000 100.63820 ?  2   DA  B OP2    1 
ATOM   1573 O  "O5'"  . DA  B 2 2  ? 23.11400  32.89200  -10.45700 1.000 102.33117 ?  2   DA  B "O5'"  1 
ATOM   1574 C  "C5'"  . DA  B 2 2  ? 24.55900  32.88000  -10.38200 1.000 101.63267 ?  2   DA  B "C5'"  1 
ATOM   1575 C  "C4'"  . DA  B 2 2  ? 24.98100  31.84600  -9.37300  1.000 94.96567  ?  2   DA  B "C4'"  1 
ATOM   1576 O  "O4'"  . DA  B 2 2  ? 24.26100  32.08400  -8.15400  1.000 89.15817  ?  2   DA  B "O4'"  1 
ATOM   1577 C  "C3'"  . DA  B 2 2  ? 24.66200  30.40200  -9.76500  1.000 90.65551  ?  2   DA  B "C3'"  1 
ATOM   1578 O  "O3'"  . DA  B 2 2  ? 25.72100  29.73200  -10.45900 1.000 91.24061  ?  2   DA  B "O3'"  1 
ATOM   1579 C  "C2'"  . DA  B 2 2  ? 24.33300  29.73200  -8.43100  1.000 83.53380  ?  2   DA  B "C2'"  1 
ATOM   1580 C  "C1'"  . DA  B 2 2  ? 24.22600  30.86600  -7.42600  1.000 81.92243  ?  2   DA  B "C1'"  1 
ATOM   1581 N  N9     . DA  B 2 2  ? 22.98500  30.84000  -6.66500  1.000 74.36706  ?  2   DA  B N9     1 
ATOM   1582 C  C8     . DA  B 2 2  ? 21.70600  30.97900  -7.13500  1.000 79.65559  ?  2   DA  B C8     1 
ATOM   1583 N  N7     . DA  B 2 2  ? 20.79700  30.90800  -6.20000  1.000 69.30346  ?  2   DA  B N7     1 
ATOM   1584 C  C5     . DA  B 2 2  ? 21.52200  30.69300  -5.04200  1.000 69.39666  ?  2   DA  B C5     1 
ATOM   1585 C  C6     . DA  B 2 2  ? 21.13000  30.51200  -3.70800  1.000 68.56366  ?  2   DA  B C6     1 
ATOM   1586 N  N6     . DA  B 2 2  ? 19.87200  30.53600  -3.28900  1.000 70.12479  ?  2   DA  B N6     1 
ATOM   1587 N  N1     . DA  B 2 2  ? 22.10700  30.30600  -2.80500  1.000 64.99809  ?  2   DA  B N1     1 
ATOM   1588 C  C2     . DA  B 2 2  ? 23.37800  30.29300  -3.21300  1.000 63.41071  ?  2   DA  B C2     1 
ATOM   1589 N  N3     . DA  B 2 2  ? 23.86600  30.44700  -4.43500  1.000 67.21291  ?  2   DA  B N3     1 
ATOM   1590 C  C4     . DA  B 2 2  ? 22.87300  30.64300  -5.31400  1.000 70.16933  ?  2   DA  B C4     1 
ATOM   1591 H  "H5'"  . DA  B 2 2  ? 24.87800  33.75400  -10.10600 1.000 121.95921 ?  2   DA  B "H5'"  1 
ATOM   1592 H  "H5''" . DA  B 2 2  ? 24.92800  32.65700  -11.25100 1.000 121.95921 ?  2   DA  B "H5''" 1 
ATOM   1593 H  "H4'"  . DA  B 2 2  ? 25.93100  31.93200  -9.20500  1.000 113.95880 ?  2   DA  B "H4'"  1 
ATOM   1594 H  "H3'"  . DA  B 2 2  ? 23.86900  30.39600  -10.32300 1.000 108.78661 ?  2   DA  B "H3'"  1 
ATOM   1595 H  "H2'"  . DA  B 2 2  ? 23.49000  29.25800  -8.49300  1.000 100.24056 ?  2   DA  B "H2'"  1 
ATOM   1596 H  "H2''" . DA  B 2 2  ? 25.04300  29.12400  -8.17500  1.000 100.24056 ?  2   DA  B "H2''" 1 
ATOM   1597 H  "H1'"  . DA  B 2 2  ? 24.98000  30.83100  -6.81700  1.000 98.30692  ?  2   DA  B "H1'"  1 
ATOM   1598 H  H8     . DA  B 2 2  ? 21.50600  31.13500  -8.03000  1.000 95.58671  ?  2   DA  B H8     1 
ATOM   1599 H  H61    . DA  B 2 2  ? 19.69400  30.42100  -2.45500  1.000 84.14975  ?  2   DA  B H61    1 
ATOM   1600 H  H62    . DA  B 2 2  ? 19.23400  30.66600  -3.85100  1.000 84.14975  ?  2   DA  B H62    1 
ATOM   1601 H  H2     . DA  B 2 2  ? 24.01000  30.15200  -2.54600  1.000 76.09285  ?  2   DA  B H2     1 
ATOM   1602 P  P      . DT  B 2 3  ? 27.23900  29.55300  -9.95200  1.000 96.89506  ?  3   DT  B P      1 
ATOM   1603 O  OP1    . DT  B 2 3  ? 27.97100  30.78200  -9.46300  1.000 96.49638  ?  3   DT  B OP1    1 
ATOM   1604 O  OP2    . DT  B 2 3  ? 27.98300  28.86900  -11.07000 1.000 98.34597  -1 3   DT  B OP2    1 
ATOM   1605 O  "O5'"  . DT  B 2 3  ? 27.23700  28.48200  -8.74300  1.000 99.16386  ?  3   DT  B "O5'"  1 
ATOM   1606 C  "C5'"  . DT  B 2 3  ? 27.83600  28.85400  -7.47400  1.000 84.36965  ?  3   DT  B "C5'"  1 
ATOM   1607 C  "C4'"  . DT  B 2 3  ? 27.70800  27.73200  -6.47100  1.000 76.87966  ?  3   DT  B "C4'"  1 
ATOM   1608 O  "O4'"  . DT  B 2 3  ? 26.47000  27.89000  -5.74200  1.000 70.48100  ?  3   DT  B "O4'"  1 
ATOM   1609 C  "C3'"  . DT  B 2 3  ? 27.68100  26.31100  -7.03400  1.000 74.49968  ?  3   DT  B "C3'"  1 
ATOM   1610 O  "O3'"  . DT  B 2 3  ? 28.30700  25.40300  -6.13700  1.000 76.96028  ?  3   DT  B "O3'"  1 
ATOM   1611 C  "C2'"  . DT  B 2 3  ? 26.19700  26.00400  -7.06500  1.000 69.23701  ?  3   DT  B "C2'"  1 
ATOM   1612 C  "C1'"  . DT  B 2 3  ? 25.77300  26.65500  -5.75800  1.000 67.13233  ?  3   DT  B "C1'"  1 
ATOM   1613 N  N1     . DT  B 2 3  ? 24.32900  26.93700  -5.59600  1.000 64.81428  ?  3   DT  B N1     1 
ATOM   1614 C  C2     . DT  B 2 3  ? 23.82200  26.96500  -4.31600  1.000 62.02880  ?  3   DT  B C2     1 
ATOM   1615 O  O2     . DT  B 2 3  ? 24.50900  26.78300  -3.32300  1.000 57.43995  ?  3   DT  B O2     1 
ATOM   1616 N  N3     . DT  B 2 3  ? 22.47700  27.21800  -4.23300  1.000 60.46488  ?  3   DT  B N3     1 
ATOM   1617 C  C4     . DT  B 2 3  ? 21.60400  27.43700  -5.27700  1.000 66.12728  ?  3   DT  B C4     1 
ATOM   1618 O  O4     . DT  B 2 3  ? 20.41600  27.65800  -5.05700  1.000 67.12486  ?  3   DT  B O4     1 
ATOM   1619 C  C5     . DT  B 2 3  ? 22.19900  27.39700  -6.58700  1.000 64.92645  ?  3   DT  B C5     1 
ATOM   1620 C  C7     . DT  B 2 3  ? 21.31900  27.62900  -7.77600  1.000 69.56050  ?  3   DT  B C7     1 
ATOM   1621 C  C6     . DT  B 2 3  ? 23.51000  27.14900  -6.68400  1.000 66.57312  ?  3   DT  B C6     1 
ATOM   1622 H  "H5'"  . DT  B 2 3  ? 27.38900  29.64300  -7.12900  1.000 101.24358 ?  3   DT  B "H5'"  1 
ATOM   1623 H  "H5''" . DT  B 2 3  ? 28.77500  29.05400  -7.61100  1.000 101.24358 ?  3   DT  B "H5''" 1 
ATOM   1624 H  "H4'"  . DT  B 2 3  ? 28.44400  27.79800  -5.84300  1.000 92.25560  ?  3   DT  B "H4'"  1 
ATOM   1625 H  "H3'"  . DT  B 2 3  ? 28.07200  26.27000  -7.92100  1.000 89.39961  ?  3   DT  B "H3'"  1 
ATOM   1626 H  "H2'"  . DT  B 2 3  ? 25.77100  26.42500  -7.82600  1.000 83.08441  ?  3   DT  B "H2'"  1 
ATOM   1627 H  "H2''" . DT  B 2 3  ? 26.03600  25.04800  -7.05000  1.000 83.08441  ?  3   DT  B "H2''" 1 
ATOM   1628 H  "H1'"  . DT  B 2 3  ? 26.07700  26.10800  -5.01700  1.000 80.55880  ?  3   DT  B "H1'"  1 
ATOM   1629 H  H3     . DT  B 2 3  ? 22.14100  27.24300  -3.44200  1.000 72.55785  ?  3   DT  B H3     1 
ATOM   1630 H  H71    . DT  B 2 3  ? 21.86800  27.76300  -8.56400  1.000 83.47260  ?  3   DT  B H71    1 
ATOM   1631 H  H72    . DT  B 2 3  ? 20.74600  26.85700  -7.90900  1.000 83.47260  ?  3   DT  B H72    1 
ATOM   1632 H  H73    . DT  B 2 3  ? 20.77200  28.41500  -7.62500  1.000 83.47260  ?  3   DT  B H73    1 
ATOM   1633 H  H6     . DT  B 2 3  ? 23.88900  27.11900  -7.53200  1.000 79.88775  ?  3   DT  B H6     1 
ATOM   1634 P  P      . DA  B 2 4  ? 29.42900  24.36500  -6.62300  1.000 71.85398  ?  4   DA  B P      1 
ATOM   1635 O  OP1    . DA  B 2 4  ? 30.54600  25.09000  -7.34900  1.000 78.26213  ?  4   DA  B OP1    1 
ATOM   1636 O  OP2    . DA  B 2 4  ? 28.86600  23.18200  -7.38700  1.000 70.79864  -1 4   DA  B OP2    1 
ATOM   1637 O  "O5'"  . DA  B 2 4  ? 30.06000  23.78700  -5.26400  1.000 69.66562  ?  4   DA  B "O5'"  1 
ATOM   1638 C  "C5'"  . DA  B 2 4  ? 30.42500  24.71200  -4.21200  1.000 66.59234  ?  4   DA  B "C5'"  1 
ATOM   1639 C  "C4'"  . DA  B 2 4  ? 29.74700  24.29000  -2.93300  1.000 62.51532  ?  4   DA  B "C4'"  1 
ATOM   1640 O  "O4'"  . DA  B 2 4  ? 28.33300  24.55800  -3.03300  1.000 67.02819  ?  4   DA  B "O4'"  1 
ATOM   1641 C  "C3'"  . DA  B 2 4  ? 29.89300  22.80700  -2.60600  1.000 60.43787  ?  4   DA  B "C3'"  1 
ATOM   1642 O  "O3'"  . DA  B 2 4  ? 30.15300  22.65900  -1.21700  1.000 58.70405  ?  4   DA  B "O3'"  1 
ATOM   1643 C  "C2'"  . DA  B 2 4  ? 28.53600  22.22400  -2.98700  1.000 59.48408  ?  4   DA  B "C2'"  1 
ATOM   1644 C  "C1'"  . DA  B 2 4  ? 27.60800  23.38300  -2.68400  1.000 57.46867  ?  4   DA  B "C1'"  1 
ATOM   1645 N  N9     . DA  B 2 4  ? 26.36500  23.38200  -3.44700  1.000 56.12759  ?  4   DA  B N9     1 
ATOM   1646 C  C8     . DA  B 2 4  ? 26.21000  23.26600  -4.80500  1.000 59.65977  ?  4   DA  B C8     1 
ATOM   1647 N  N7     . DA  B 2 4  ? 24.96100  23.31600  -5.19200  1.000 56.79843  ?  4   DA  B N7     1 
ATOM   1648 C  C5     . DA  B 2 4  ? 24.24600  23.47800  -4.01600  1.000 48.77286  ?  4   DA  B C5     1 
ATOM   1649 C  C6     . DA  B 2 4  ? 22.87000  23.59800  -3.75800  1.000 46.53436  ?  4   DA  B C6     1 
ATOM   1650 N  N6     . DA  B 2 4  ? 21.93100  23.57600  -4.69800  1.000 51.56609  ?  4   DA  B N6     1 
ATOM   1651 N  N1     . DA  B 2 4  ? 22.49500  23.74700  -2.46900  1.000 50.53739  ?  4   DA  B N1     1 
ATOM   1652 C  C2     . DA  B 2 4  ? 23.43400  23.77200  -1.51900  1.000 52.63098  ?  4   DA  B C2     1 
ATOM   1653 N  N3     . DA  B 2 4  ? 24.75200  23.66900  -1.64200  1.000 56.20661  ?  4   DA  B N3     1 
ATOM   1654 C  C4     . DA  B 2 4  ? 25.09900  23.52300  -2.93000  1.000 48.61284  ?  4   DA  B C4     1 
ATOM   1655 H  "H5'"  . DA  B 2 4  ? 30.13800  25.60700  -4.45200  1.000 79.91080  ?  4   DA  B "H5'"  1 
ATOM   1656 H  "H5''" . DA  B 2 4  ? 31.38700  24.70100  -4.08900  1.000 79.91080  ?  4   DA  B "H5''" 1 
ATOM   1657 H  "H4'"  . DA  B 2 4  ? 30.11300  24.80900  -2.20000  1.000 75.01838  ?  4   DA  B "H4'"  1 
ATOM   1658 H  "H3'"  . DA  B 2 4  ? 30.60100  22.40700  -3.13500  1.000 72.52544  ?  4   DA  B "H3'"  1 
ATOM   1659 H  "H2'"  . DA  B 2 4  ? 28.51000  21.99600  -3.92900  1.000 71.38089  ?  4   DA  B "H2'"  1 
ATOM   1660 H  "H2''" . DA  B 2 4  ? 28.32200  21.45500  -2.43600  1.000 71.38089  ?  4   DA  B "H2''" 1 
ATOM   1661 H  "H1'"  . DA  B 2 4  ? 27.40600  23.39700  -1.73500  1.000 68.96241  ?  4   DA  B "H1'"  1 
ATOM   1662 H  H8     . DA  B 2 4  ? 26.92300  23.16300  -5.39300  1.000 71.59173  ?  4   DA  B H8     1 
ATOM   1663 H  H61    . DA  B 2 4  ? 21.10300  23.65600  -4.48000  1.000 61.87931  ?  4   DA  B H61    1 
ATOM   1664 H  H62    . DA  B 2 4  ? 22.15100  23.48200  -5.52400  1.000 61.87931  ?  4   DA  B H62    1 
ATOM   1665 H  H2     . DA  B 2 4  ? 23.12100  23.87800  -0.65000  1.000 63.15717  ?  4   DA  B H2     1 
ATOM   1666 P  P      . DA  B 2 5  ? 30.57200  21.24000  -0.59100  1.000 63.08551  ?  5   DA  B P      1 
ATOM   1667 O  OP1    . DA  B 2 5  ? 31.60900  21.50500  0.45400   1.000 55.81687  ?  5   DA  B OP1    1 
ATOM   1668 O  OP2    . DA  B 2 5  ? 30.76900  20.22600  -1.65000  1.000 55.35695  -1 5   DA  B OP2    1 
ATOM   1669 O  "O5'"  . DA  B 2 5  ? 29.22400  20.80400  0.10500   1.000 53.26044  ?  5   DA  B "O5'"  1 
ATOM   1670 C  "C5'"  . DA  B 2 5  ? 28.75500  21.53100  1.20700   1.000 48.32608  ?  5   DA  B "C5'"  1 
ATOM   1671 C  "C4'"  . DA  B 2 5  ? 27.34800  21.15100  1.50600   1.000 48.80484  ?  5   DA  B "C4'"  1 
ATOM   1672 O  "O4'"  . DA  B 2 5  ? 26.54700  21.21300  0.32200   1.000 49.18015  ?  5   DA  B "O4'"  1 
ATOM   1673 C  "C3'"  . DA  B 2 5  ? 27.15300  19.73800  2.03700   1.000 47.85857  ?  5   DA  B "C3'"  1 
ATOM   1674 O  "O3'"  . DA  B 2 5  ? 27.01200  19.85400  3.44700   1.000 45.52547  ?  5   DA  B "O3'"  1 
ATOM   1675 C  "C2'"  . DA  B 2 5  ? 25.88100  19.22500  1.30200   1.000 48.80769  ?  5   DA  B "C2'"  1 
ATOM   1676 C  "C1'"  . DA  B 2 5  ? 25.38400  20.45000  0.56100   1.000 48.68919  ?  5   DA  B "C1'"  1 
ATOM   1677 N  N9     . DA  B 2 5  ? 24.76200  20.26100  -0.73100  1.000 43.08939  ?  5   DA  B N9     1 
ATOM   1678 C  C8     . DA  B 2 5  ? 25.39800  20.02600  -1.92100  1.000 42.53901  ?  5   DA  B C8     1 
ATOM   1679 N  N7     . DA  B 2 5  ? 24.58500  20.00100  -2.97200  1.000 43.23326  ?  5   DA  B N7     1 
ATOM   1680 C  C5     . DA  B 2 5  ? 23.34300  20.31700  -2.43100  1.000 39.87965  ?  5   DA  B C5     1 
ATOM   1681 C  C6     . DA  B 2 5  ? 22.06300  20.44500  -3.00100  1.000 38.62831  ?  5   DA  B C6     1 
ATOM   1682 N  N6     . DA  B 2 5  ? 21.81900  20.31000  -4.29300  1.000 41.75354  ?  5   DA  B N6     1 
ATOM   1683 N  N1     . DA  B 2 5  ? 21.04000  20.70600  -2.19500  1.000 36.64533  ?  5   DA  B N1     1 
ATOM   1684 C  C2     . DA  B 2 5  ? 21.27400  20.86300  -0.87800  1.000 38.89593  ?  5   DA  B C2     1 
ATOM   1685 N  N3     . DA  B 2 5  ? 22.43700  20.78100  -0.20700  1.000 38.56611  ?  5   DA  B N3     1 
ATOM   1686 C  C4     . DA  B 2 5  ? 23.43600  20.46600  -1.04100  1.000 40.56352  ?  5   DA  B C4     1 
ATOM   1687 H  "H5'"  . DA  B 2 5  ? 28.79700  22.47900  1.00800   1.000 57.99129  ?  5   DA  B "H5'"  1 
ATOM   1688 H  "H5''" . DA  B 2 5  ? 29.31100  21.34000  1.97900   1.000 57.99129  ?  5   DA  B "H5''" 1 
ATOM   1689 H  "H4'"  . DA  B 2 5  ? 26.99000  21.77700  2.15500   1.000 58.56581  ?  5   DA  B "H4'"  1 
ATOM   1690 H  "H3'"  . DA  B 2 5  ? 27.91900  19.18600  1.81600   1.000 57.43028  ?  5   DA  B "H3'"  1 
ATOM   1691 H  "H2'"  . DA  B 2 5  ? 26.10900  18.51700  0.67900   1.000 58.56923  ?  5   DA  B "H2'"  1 
ATOM   1692 H  "H2''" . DA  B 2 5  ? 25.21700  18.92100  1.93700   1.000 58.56923  ?  5   DA  B "H2''" 1 
ATOM   1693 H  "H1'"  . DA  B 2 5  ? 24.78500  20.95100  1.13600   1.000 58.42703  ?  5   DA  B "H1'"  1 
ATOM   1694 H  H8     . DA  B 2 5  ? 26.31300  19.87000  -1.98400  1.000 51.04681  ?  5   DA  B H8     1 
ATOM   1695 H  H61    . DA  B 2 5  ? 21.01600  20.39100  -4.59000  1.000 50.10425  ?  5   DA  B H61    1 
ATOM   1696 H  H62    . DA  B 2 5  ? 22.46300  20.14100  -4.83700  1.000 50.10425  ?  5   DA  B H62    1 
ATOM   1697 H  H2     . DA  B 2 5  ? 20.52900  21.07100  -0.36200  1.000 46.67511  ?  5   DA  B H2     1 
ATOM   1698 P  P      . DA  B 2 6  ? 26.68900  18.59000  4.39000   1.000 52.23499  ?  6   DA  B P      1 
ATOM   1699 O  OP1    . DA  B 2 6  ? 26.86700  19.20600  5.72600   1.000 48.31135  ?  6   DA  B OP1    1 
ATOM   1700 O  OP2    . DA  B 2 6  ? 27.38100  17.33800  3.92800   1.000 45.31449  -1 6   DA  B OP2    1 
ATOM   1701 O  "O5'"  . DA  B 2 6  ? 25.12500  18.26200  4.12900   1.000 44.44031  ?  6   DA  B "O5'"  1 
ATOM   1702 C  "C5'"  . DA  B 2 6  ? 24.12600  19.24300  4.44300   1.000 39.43060  ?  6   DA  B "C5'"  1 
ATOM   1703 C  "C4'"  . DA  B 2 6  ? 22.72700  18.69300  4.17100   1.000 39.17657  ?  6   DA  B "C4'"  1 
ATOM   1704 O  "O4'"  . DA  B 2 6  ? 22.41800  18.72900  2.73800   1.000 40.58617  ?  6   DA  B "O4'"  1 
ATOM   1705 C  "C3'"  . DA  B 2 6  ? 22.51100  17.24400  4.59300   1.000 34.84726  ?  6   DA  B "C3'"  1 
ATOM   1706 O  "O3'"  . DA  B 2 6  ? 21.43900  17.24000  5.50700   1.000 37.37530  ?  6   DA  B "O3'"  1 
ATOM   1707 C  "C2'"  . DA  B 2 6  ? 22.23200  16.46000  3.30500   1.000 37.52659  ?  6   DA  B "C2'"  1 
ATOM   1708 C  "C1'"  . DA  B 2 6  ? 21.76700  17.51600  2.34700   1.000 34.79060  ?  6   DA  B "C1'"  1 
ATOM   1709 N  N9     . DA  B 2 6  ? 22.07800  17.30100  0.93100   1.000 32.28745  ?  6   DA  B N9     1 
ATOM   1710 C  C8     . DA  B 2 6  ? 23.28100  17.08300  0.38700   1.000 32.73922  ?  6   DA  B C8     1 
ATOM   1711 N  N7     . DA  B 2 6  ? 23.26600  17.02900  -0.92600  1.000 39.68175  ?  6   DA  B N7     1 
ATOM   1712 C  C5     . DA  B 2 6  ? 21.94700  17.24200  -1.26200  1.000 34.51441  ?  6   DA  B C5     1 
ATOM   1713 C  C6     . DA  B 2 6  ? 21.24100  17.29600  -2.52300  1.000 32.42045  ?  6   DA  B C6     1 
ATOM   1714 N  N6     . DA  B 2 6  ? 21.81800  17.13100  -3.71300  1.000 35.60063  ?  6   DA  B N6     1 
ATOM   1715 N  N1     . DA  B 2 6  ? 19.91000  17.51600  -2.49100  1.000 32.17405  ?  6   DA  B N1     1 
ATOM   1716 C  C2     . DA  B 2 6  ? 19.31100  17.69800  -1.30000  1.000 35.60905  ?  6   DA  B C2     1 
ATOM   1717 N  N3     . DA  B 2 6  ? 19.86600  17.67600  -0.05500  1.000 32.82544  ?  6   DA  B N3     1 
ATOM   1718 C  C4     . DA  B 2 6  ? 21.20200  17.43200  -0.11800  1.000 32.47388  ?  6   DA  B C4     1 
ATOM   1719 H  "H5'"  . DA  B 2 6  ? 24.27100  20.03200  3.89800   1.000 47.31672  ?  6   DA  B "H5'"  1 
ATOM   1720 H  "H5''" . DA  B 2 6  ? 24.19800  19.48400  5.38000   1.000 47.31672  ?  6   DA  B "H5''" 1 
ATOM   1721 H  "H4'"  . DA  B 2 6  ? 22.08300  19.24800  4.63800   1.000 47.01188  ?  6   DA  B "H4'"  1 
ATOM   1722 H  "H3'"  . DA  B 2 6  ? 23.31100  16.90200  5.02100   1.000 41.81672  ?  6   DA  B "H3'"  1 
ATOM   1723 H  "H2'"  . DA  B 2 6  ? 23.04200  16.03700  2.98100   1.000 45.03191  ?  6   DA  B "H2'"  1 
ATOM   1724 H  "H2''" . DA  B 2 6  ? 21.53600  15.80100  3.45100   1.000 45.03191  ?  6   DA  B "H2''" 1 
ATOM   1725 H  "H1'"  . DA  B 2 6  ? 20.80800  17.62800  2.44500   1.000 41.74872  ?  6   DA  B "H1'"  1 
ATOM   1726 H  H8     . DA  B 2 6  ? 24.05700  16.98800  0.89100   1.000 39.28707  ?  6   DA  B H8     1 
ATOM   1727 H  H61    . DA  B 2 6  ? 21.34400  17.16600  -4.42900  1.000 42.72076  ?  6   DA  B H61    1 
ATOM   1728 H  H62    . DA  B 2 6  ? 22.66500  16.98900  -3.76400  1.000 42.72076  ?  6   DA  B H62    1 
ATOM   1729 H  H2     . DA  B 2 6  ? 18.39600  17.86100  -1.33000  1.000 42.73087  ?  6   DA  B H2     1 
ATOM   1730 P  P      . DA  B 2 7  ? 20.94000  15.93100  6.26800   1.000 38.85537  ?  7   DA  B P      1 
ATOM   1731 O  OP1    . DA  B 2 7  ? 20.21000  16.53500  7.40200   1.000 45.49230  ?  7   DA  B OP1    1 
ATOM   1732 O  OP2    . DA  B 2 7  ? 22.03500  14.98100  6.55800   1.000 37.01809  -1 7   DA  B OP2    1 
ATOM   1733 O  "O5'"  . DA  B 2 7  ? 19.84700  15.28600  5.27200   1.000 39.53357  ?  7   DA  B "O5'"  1 
ATOM   1734 C  "C5'"  . DA  B 2 7  ? 18.92500  16.12900  4.66000   1.000 38.99149  ?  7   DA  B "C5'"  1 
ATOM   1735 C  "C4'"  . DA  B 2 7  ? 18.08100  15.41000  3.60000   1.000 36.55136  ?  7   DA  B "C4'"  1 
ATOM   1736 O  "O4'"  . DA  B 2 7  ? 18.73600  15.49400  2.32400   1.000 37.50205  ?  7   DA  B "O4'"  1 
ATOM   1737 C  "C3'"  . DA  B 2 7  ? 17.85800  13.92900  3.84400   1.000 37.62406  ?  7   DA  B "C3'"  1 
ATOM   1738 O  "O3'"  . DA  B 2 7  ? 16.58400  13.71500  4.41300   1.000 41.07326  ?  7   DA  B "O3'"  1 
ATOM   1739 C  "C2'"  . DA  B 2 7  ? 18.00100  13.27200  2.44100   1.000 38.38787  ?  7   DA  B "C2'"  1 
ATOM   1740 C  "C1'"  . DA  B 2 7  ? 18.22300  14.45700  1.50400   1.000 33.01563  ?  7   DA  B "C1'"  1 
ATOM   1741 N  N9     . DA  B 2 7  ? 19.16200  14.25900  0.46000   1.000 35.06735  ?  7   DA  B N9     1 
ATOM   1742 C  C8     . DA  B 2 7  ? 20.54700  14.19700  0.56600   1.000 34.55322  ?  7   DA  B C8     1 
ATOM   1743 N  N7     . DA  B 2 7  ? 21.14100  14.07400  -0.59100  1.000 35.75451  ?  7   DA  B N7     1 
ATOM   1744 C  C5     . DA  B 2 7  ? 20.09200  14.07500  -1.48900  1.000 32.93938  ?  7   DA  B C5     1 
ATOM   1745 C  C6     . DA  B 2 7  ? 20.05300  14.01800  -2.91700  1.000 35.19544  ?  7   DA  B C6     1 
ATOM   1746 N  N6     . DA  B 2 7  ? 21.14300  13.86300  -3.68300  1.000 31.70744  ?  7   DA  B N6     1 
ATOM   1747 N  N1     . DA  B 2 7  ? 18.86800  14.05700  -3.50400  1.000 35.13224  ?  7   DA  B N1     1 
ATOM   1748 C  C2     . DA  B 2 7  ? 17.76900  14.16200  -2.75300  1.000 33.70299  ?  7   DA  B C2     1 
ATOM   1749 N  N3     . DA  B 2 7  ? 17.68000  14.27100  -1.43300  1.000 39.66475  ?  7   DA  B N3     1 
ATOM   1750 C  C4     . DA  B 2 7  ? 18.89200  14.22400  -0.86400  1.000 33.39582  ?  7   DA  B C4     1 
ATOM   1751 H  "H5'"  . DA  B 2 7  ? 19.40100  16.86000  4.23700   1.000 46.78978  ?  7   DA  B "H5'"  1 
ATOM   1752 H  "H5''" . DA  B 2 7  ? 18.33400  16.49100  5.33800   1.000 46.78978  ?  7   DA  B "H5''" 1 
ATOM   1753 H  "H4'"  . DA  B 2 7  ? 17.21800  15.84900  3.53800   1.000 43.86163  ?  7   DA  B "H4'"  1 
ATOM   1754 H  "H3'"  . DA  B 2 7  ? 18.54300  13.58500  4.43700   1.000 45.14887  ?  7   DA  B "H3'"  1 
ATOM   1755 H  "H2'"  . DA  B 2 7  ? 18.76400  12.67400  2.42100   1.000 46.06545  ?  7   DA  B "H2'"  1 
ATOM   1756 H  "H2''" . DA  B 2 7  ? 17.18900  12.79800  2.20300   1.000 46.06545  ?  7   DA  B "H2''" 1 
ATOM   1757 H  "H1'"  . DA  B 2 7  ? 17.37400  14.73500  1.12700   1.000 39.61875  ?  7   DA  B "H1'"  1 
ATOM   1758 H  H8     . DA  B 2 7  ? 21.00100  14.21500  1.37700   1.000 41.46386  ?  7   DA  B H8     1 
ATOM   1759 H  H61    . DA  B 2 7  ? 21.06200  13.79000  -4.53600  1.000 38.04893  ?  7   DA  B H61    1 
ATOM   1760 H  H62    . DA  B 2 7  ? 21.92300  13.83700  -3.32100  1.000 38.04893  ?  7   DA  B H62    1 
ATOM   1761 H  H2     . DA  B 2 7  ? 16.96500  14.20600  -3.21800  1.000 40.44359  ?  7   DA  B H2     1 
ATOM   1762 P  P      . DG  B 2 8  ? 16.23500  12.25600  5.00900   1.000 53.64768  ?  8   DG  B P      1 
ATOM   1763 O  OP1    . DG  B 2 8  ? 15.12000  12.39900  5.96900   1.000 51.59076  ?  8   DG  B OP1    1 
ATOM   1764 O  OP2    . DG  B 2 8  ? 17.51700  11.54700  5.23400   1.000 46.14321  -1 8   DG  B OP2    1 
ATOM   1765 O  "O5'"  . DG  B 2 8  ? 15.73700  11.40100  3.74000   1.000 54.98656  ?  8   DG  B "O5'"  1 
ATOM   1766 C  "C5'"  . DG  B 2 8  ? 14.61700  11.82100  2.96100   1.000 51.10839  ?  8   DG  B "C5'"  1 
ATOM   1767 C  "C4'"  . DG  B 2 8  ? 14.47300  10.86300  1.81200   1.000 45.83356  ?  8   DG  B "C4'"  1 
ATOM   1768 O  "O4'"  . DG  B 2 8  ? 15.46000  11.22300  0.76800   1.000 44.84304  ?  8   DG  B "O4'"  1 
ATOM   1769 C  "C3'"  . DG  B 2 8  ? 14.77900  9.38500   2.19900   1.000 49.56573  ?  8   DG  B "C3'"  1 
ATOM   1770 O  "O3'"  . DG  B 2 8  ? 13.99900  8.46000   1.45700   1.000 49.11292  ?  8   DG  B "O3'"  1 
ATOM   1771 C  "C2'"  . DG  B 2 8  ? 16.24200  9.26000   1.81000   1.000 44.13019  ?  8   DG  B "C2'"  1 
ATOM   1772 C  "C1'"  . DG  B 2 8  ? 16.19300  10.04400  0.45900   1.000 41.39858  ?  8   DG  B "C1'"  1 
ATOM   1773 N  N9     . DG  B 2 8  ? 17.50200  10.30600  -0.07300  1.000 35.05167  ?  8   DG  B N9     1 
ATOM   1774 C  C8     . DG  B 2 8  ? 18.66600  10.39400  0.62400   1.000 31.77616  ?  8   DG  B C8     1 
ATOM   1775 N  N7     . DG  B 2 8  ? 19.71400  10.59300  -0.12700  1.000 34.74525  ?  8   DG  B N7     1 
ATOM   1776 C  C5     . DG  B 2 8  ? 19.20100  10.58500  -1.46100  1.000 31.19733  ?  8   DG  B C5     1 
ATOM   1777 C  C6     . DG  B 2 8  ? 19.83100  10.73500  -2.72400  1.000 35.10795  ?  8   DG  B C6     1 
ATOM   1778 O  O6     . DG  B 2 8  ? 21.04200  10.89300  -2.99700  1.000 34.75042  ?  8   DG  B O6     1 
ATOM   1779 N  N1     . DG  B 2 8  ? 18.88800  10.68700  -3.78600  1.000 33.28855  ?  8   DG  B N1     1 
ATOM   1780 C  C2     . DG  B 2 8  ? 17.51100  10.49100  -3.59400  1.000 36.02414  ?  8   DG  B C2     1 
ATOM   1781 N  N2     . DG  B 2 8  ? 16.73600  10.43000  -4.68400  1.000 32.72860  ?  8   DG  B N2     1 
ATOM   1782 N  N3     . DG  B 2 8  ? 16.95000  10.33900  -2.41100  1.000 36.83219  ?  8   DG  B N3     1 
ATOM   1783 C  C4     . DG  B 2 8  ? 17.82900  10.40300  -1.41000  1.000 35.77575  ?  8   DG  B C4     1 
ATOM   1784 H  "H5'"  . DG  B 2 8  ? 14.76900  12.71800  2.62400   1.000 61.33007  ?  8   DG  B "H5'"  1 
ATOM   1785 H  "H5''" . DG  B 2 8  ? 13.81400  11.80500  3.50500   1.000 61.33007  ?  8   DG  B "H5''" 1 
ATOM   1786 H  "H4'"  . DG  B 2 8  ? 13.57700  10.92500  1.44700   1.000 55.00028  ?  8   DG  B "H4'"  1 
ATOM   1787 H  "H3'"  . DG  B 2 8  ? 14.66500  9.24800   3.15200   1.000 59.47887  ?  8   DG  B "H3'"  1 
ATOM   1788 H  "H2'"  . DG  B 2 8  ? 16.81800  9.69800   2.45500   1.000 52.95622  ?  8   DG  B "H2'"  1 
ATOM   1789 H  "H2''" . DG  B 2 8  ? 16.49400  8.33300   1.67300   1.000 52.95622  ?  8   DG  B "H2''" 1 
ATOM   1790 H  "H1'"  . DG  B 2 8  ? 15.69100  9.52300   -0.18700  1.000 49.67829  ?  8   DG  B "H1'"  1 
ATOM   1791 H  H8     . DG  B 2 8  ? 18.70700  10.35000  1.55200   1.000 38.13139  ?  8   DG  B H8     1 
ATOM   1792 H  H1     . DG  B 2 8  ? 19.18000  10.75800  -4.59200  1.000 39.94626  ?  8   DG  B H1     1 
ATOM   1793 H  H21    . DG  B 2 8  ? 15.89100  10.29400  -4.60300  1.000 39.27432  ?  8   DG  B H21    1 
ATOM   1794 H  H22    . DG  B 2 8  ? 17.08400  10.52700  -5.46500  1.000 39.27432  ?  8   DG  B H22    1 
ATOM   1795 P  P      . DG  B 2 9  ? 12.82500  7.62100   2.17600   1.000 56.79325  ?  9   DG  B P      1 
ATOM   1796 O  OP1    . DG  B 2 9  ? 11.85500  8.68400   2.58600   1.000 47.33696  ?  9   DG  B OP1    1 
ATOM   1797 O  OP2    . DG  B 2 9  ? 13.44500  6.60500   3.06900   1.000 44.89914  -1 9   DG  B OP2    1 
ATOM   1798 O  "O5'"  . DG  B 2 9  ? 12.12300  6.86900   0.94300   1.000 53.31352  ?  9   DG  B "O5'"  1 
ATOM   1799 C  "C5'"  . DG  B 2 9  ? 11.48200  7.66700   -0.02900  1.000 52.96082  ?  9   DG  B "C5'"  1 
ATOM   1800 C  "C4'"  . DG  B 2 9  ? 11.76800  7.15600   -1.42700  1.000 58.32704  ?  9   DG  B "C4'"  1 
ATOM   1801 O  "O4'"  . DG  B 2 9  ? 13.11400  7.51800   -1.81500  1.000 55.05166  ?  9   DG  B "O4'"  1 
ATOM   1802 C  "C3'"  . DG  B 2 9  ? 11.67300  5.64100   -1.58500  1.000 57.09416  ?  9   DG  B "C3'"  1 
ATOM   1803 O  "O3'"  . DG  B 2 9  ? 10.76000  5.31600   -2.64800  1.000 68.99643  ?  9   DG  B "O3'"  1 
ATOM   1804 C  "C2'"  . DG  B 2 9  ? 13.11800  5.17400   -1.87100  1.000 53.74866  ?  9   DG  B "C2'"  1 
ATOM   1805 C  "C1'"  . DG  B 2 9  ? 13.77000  6.40800   -2.42200  1.000 50.17900  ?  9   DG  B "C1'"  1 
ATOM   1806 N  N9     . DG  B 2 9  ? 15.22000  6.57100   -2.15900  1.000 46.61369  ?  9   DG  B N9     1 
ATOM   1807 C  C8     . DG  B 2 9  ? 15.83100  6.71800   -0.93800  1.000 42.37341  ?  9   DG  B C8     1 
ATOM   1808 N  N7     . DG  B 2 9  ? 17.11100  6.94500   -1.01200  1.000 39.55418  ?  9   DG  B N7     1 
ATOM   1809 C  C5     . DG  B 2 9  ? 17.37400  6.96600   -2.37100  1.000 39.73577  ?  9   DG  B C5     1 
ATOM   1810 C  C6     . DG  B 2 9  ? 18.60200  7.15100   -3.04900  1.000 36.71564  ?  9   DG  B C6     1 
ATOM   1811 O  O6     . DG  B 2 9  ? 19.74100  7.36300   -2.54300  1.000 35.52754  ?  9   DG  B O6     1 
ATOM   1812 N  N1     . DG  B 2 9  ? 18.43500  7.11100   -4.43800  1.000 33.87492  ?  9   DG  B N1     1 
ATOM   1813 C  C2     . DG  B 2 9  ? 17.19600  6.89600   -5.07600  1.000 42.08125  ?  9   DG  B C2     1 
ATOM   1814 N  N2     . DG  B 2 9  ? 17.20200  6.85400   -6.41700  1.000 39.27759  ?  9   DG  B N2     1 
ATOM   1815 N  N3     . DG  B 2 9  ? 16.04500  6.73300   -4.42500  1.000 38.76715  ?  9   DG  B N3     1 
ATOM   1816 C  C4     . DG  B 2 9  ? 16.21300  6.76900   -3.08700  1.000 41.78212  ?  9   DG  B C4     1 
ATOM   1817 H  "H5'"  . DG  B 2 9  ? 11.80100  8.58000   0.04800   1.000 63.55299  ?  9   DG  B "H5'"  1 
ATOM   1818 H  "H5''" . DG  B 2 9  ? 10.52500  7.65000   0.12600   1.000 63.55299  ?  9   DG  B "H5''" 1 
ATOM   1819 H  "H4'"  . DG  B 2 9  ? 11.14500  7.57200   -2.04300  1.000 69.99244  ?  9   DG  B "H4'"  1 
ATOM   1820 H  "H3'"  . DG  B 2 9  ? 11.36100  5.24600   -0.75600  1.000 68.51300  ?  9   DG  B "H3'"  1 
ATOM   1821 H  "H2'"  . DG  B 2 9  ? 13.55500  4.89200   -1.05200  1.000 64.49839  ?  9   DG  B "H2'"  1 
ATOM   1822 H  "H2''" . DG  B 2 9  ? 13.12400  4.46100   -2.52900  1.000 64.49839  ?  9   DG  B "H2''" 1 
ATOM   1823 H  "H1'"  . DG  B 2 9  ? 13.62000  6.44000   -3.38000  1.000 60.21480  ?  9   DG  B "H1'"  1 
ATOM   1824 H  H8     . DG  B 2 9  ? 15.37000  6.67000   -0.13200  1.000 50.84809  ?  9   DG  B H8     1 
ATOM   1825 H  H1     . DG  B 2 9  ? 19.13200  7.21300   -4.93200  1.000 40.64990  ?  9   DG  B H1     1 
ATOM   1826 H  H21    . DG  B 2 9  ? 16.46800  6.72300   -6.84600  1.000 47.13311  ?  9   DG  B H21    1 
ATOM   1827 H  H22    . DG  B 2 9  ? 17.93900  6.95800   -6.84700  1.000 47.13311  ?  9   DG  B H22    1 
ATOM   1828 P  P      . DA  B 2 10 ? 10.16000  3.82500   -2.78700  1.000 68.80131  ?  10  DA  B P      1 
ATOM   1829 O  OP1    . DA  B 2 10 ? 8.82000   3.99300   -3.42800  1.000 66.62362  ?  10  DA  B OP1    1 
ATOM   1830 O  OP2    . DA  B 2 10 ? 10.37600  3.09600   -1.50500  1.000 61.55669  -1 10  DA  B OP2    1 
ATOM   1831 O  "O5'"  . DA  B 2 10 ? 11.15500  3.08400   -3.79600  1.000 65.04698  ?  10  DA  B "O5'"  1 
ATOM   1832 C  "C5'"  . DA  B 2 10 ? 11.58700  3.73600   -4.96200  1.000 66.67105  ?  10  DA  B "C5'"  1 
ATOM   1833 C  "C4'"  . DA  B 2 10 ? 12.71900  2.96900   -5.59900  1.000 66.64726  ?  10  DA  B "C4'"  1 
ATOM   1834 O  "O4'"  . DA  B 2 10 ? 13.97500  3.45700   -5.07500  1.000 61.87276  ?  10  DA  B "O4'"  1 
ATOM   1835 C  "C3'"  . DA  B 2 10 ? 12.70800  1.45600   -5.34200  1.000 68.51010  ?  10  DA  B "C3'"  1 
ATOM   1836 O  "O3'"  . DA  B 2 10 ? 12.76200  0.78000   -6.58500  1.000 74.61392  ?  10  DA  B "O3'"  1 
ATOM   1837 C  "C2'"  . DA  B 2 10 ? 13.94600  1.18300   -4.47400  1.000 64.21911  ?  10  DA  B "C2'"  1 
ATOM   1838 C  "C1'"  . DA  B 2 10 ? 14.85300  2.35400   -4.85700  1.000 63.98398  ?  10  DA  B "C1'"  1 
ATOM   1839 N  N9     . DA  B 2 10 ? 15.86900  2.75000   -3.87100  1.000 55.87422  ?  10  DA  B N9     1 
ATOM   1840 C  C8     . DA  B 2 10 ? 15.74700  2.86400   -2.50200  1.000 45.18210  ?  10  DA  B C8     1 
ATOM   1841 N  N7     . DA  B 2 10 ? 16.86000  3.27400   -1.90100  1.000 48.06731  ?  10  DA  B N7     1 
ATOM   1842 C  C5     . DA  B 2 10 ? 17.76400  3.45900   -2.95300  1.000 44.26222  ?  10  DA  B C5     1 
ATOM   1843 C  C6     . DA  B 2 10 ? 19.11900  3.88700   -3.01800  1.000 40.96510  ?  10  DA  B C6     1 
ATOM   1844 N  N6     . DA  B 2 10 ? 19.85400  4.22400   -1.95700  1.000 38.46835  ?  10  DA  B N6     1 
ATOM   1845 N  N1     . DA  B 2 10 ? 19.68800  3.97500   -4.24600  1.000 38.86320  ?  10  DA  B N1     1 
ATOM   1846 C  C2     . DA  B 2 10 ? 18.96200  3.62600   -5.33000  1.000 43.12847  ?  10  DA  B C2     1 
ATOM   1847 N  N3     . DA  B 2 10 ? 17.71000  3.21200   -5.38700  1.000 45.28604  ?  10  DA  B N3     1 
ATOM   1848 C  C4     . DA  B 2 10 ? 17.16100  3.15500   -4.17000  1.000 47.83729  ?  10  DA  B C4     1 
ATOM   1849 H  "H5'"  . DA  B 2 10 ? 11.89100  4.62900   -4.73700  1.000 80.00526  ?  10  DA  B "H5'"  1 
ATOM   1850 H  "H5''" . DA  B 2 10 ? 10.84800  3.79700   -5.58800  1.000 80.00526  ?  10  DA  B "H5''" 1 
ATOM   1851 H  "H4'"  . DA  B 2 10 ? 12.70000  3.12300   -6.55700  1.000 79.97671  ?  10  DA  B "H4'"  1 
ATOM   1852 H  "H3'"  . DA  B 2 10 ? 11.90400  1.20400   -4.86300  1.000 82.21212  ?  10  DA  B "H3'"  1 
ATOM   1853 H  "H2'"  . DA  B 2 10 ? 13.72100  1.21100   -3.53100  1.000 77.06294  ?  10  DA  B "H2'"  1 
ATOM   1854 H  "H2''" . DA  B 2 10 ? 14.35100  0.33800   -4.71100  1.000 77.06294  ?  10  DA  B "H2''" 1 
ATOM   1855 H  "H1'"  . DA  B 2 10 ? 15.29800  2.14100   -5.69200  1.000 76.78077  ?  10  DA  B "H1'"  1 
ATOM   1856 H  H8     . DA  B 2 10 ? 14.96900  2.64800   -2.04000  1.000 54.21852  ?  10  DA  B H8     1 
ATOM   1857 H  H61    . DA  B 2 10 ? 20.66600  4.48800   -2.06300  1.000 46.16202  ?  10  DA  B H61    1 
ATOM   1858 H  H62    . DA  B 2 10 ? 19.51600  4.17700   -1.16700  1.000 46.16202  ?  10  DA  B H62    1 
ATOM   1859 H  H2     . DA  B 2 10 ? 19.40200  3.69100   -6.14700  1.000 51.75417  ?  10  DA  B H2     1 
ATOM   1860 P  P      . DA  B 2 11 ? 12.12300  -0.68200  -6.78600  1.000 78.94722  ?  11  DA  B P      1 
ATOM   1861 O  OP1    . DA  B 2 11 ? 10.94300  -0.66000  -7.73700  1.000 84.69429  ?  11  DA  B OP1    1 
ATOM   1862 O  OP2    . DA  B 2 11 ? 11.85500  -1.42600  -5.49000  1.000 74.98275  -1 11  DA  B OP2    1 
ATOM   1863 O  "O5'"  . DA  B 2 11 ? 13.30500  -1.47800  -7.53200  1.000 76.79776  ?  11  DA  B "O5'"  1 
ATOM   1864 C  "C5'"  . DA  B 2 11 ? 13.84100  -0.93600  -8.76200  1.000 75.66941  ?  11  DA  B "C5'"  1 
ATOM   1865 C  "C4'"  . DA  B 2 11 ? 15.34500  -0.99100  -8.70400  1.000 66.85843  ?  11  DA  B "C4'"  1 
ATOM   1866 O  "O4'"  . DA  B 2 11 ? 15.80700  -0.31200  -7.51600  1.000 64.22061  ?  11  DA  B "O4'"  1 
ATOM   1867 C  "C3'"  . DA  B 2 11 ? 15.92300  -2.40700  -8.63200  1.000 68.22928  ?  11  DA  B "C3'"  1 
ATOM   1868 O  "O3'"  . DA  B 2 11 ? 17.01100  -2.56900  -9.53500  1.000 67.04488  ?  11  DA  B "O3'"  1 
ATOM   1869 C  "C2'"  . DA  B 2 11 ? 16.43600  -2.48200  -7.20000  1.000 62.89066  ?  11  DA  B "C2'"  1 
ATOM   1870 C  "C1'"  . DA  B 2 11 ? 16.92300  -1.06400  -7.06600  1.000 53.89634  ?  11  DA  B "C1'"  1 
ATOM   1871 N  N9     . DA  B 2 11 ? 17.30800  -0.68400  -5.71700  1.000 60.86475  ?  11  DA  B N9     1 
ATOM   1872 C  C8     . DA  B 2 11 ? 16.66600  -0.83100  -4.51600  1.000 54.57125  ?  11  DA  B C8     1 
ATOM   1873 N  N7     . DA  B 2 11 ? 17.36200  -0.38200  -3.50400  1.000 49.68560  ?  11  DA  B N7     1 
ATOM   1874 C  C5     . DA  B 2 11 ? 18.55000  0.05100   -4.07200  1.000 51.54911  ?  11  DA  B C5     1 
ATOM   1875 C  C6     . DA  B 2 11 ? 19.70400  0.62400   -3.52000  1.000 43.47532  ?  11  DA  B C6     1 
ATOM   1876 N  N6     . DA  B 2 11 ? 19.85600  0.86000   -2.22100  1.000 47.95983  ?  11  DA  B N6     1 
ATOM   1877 N  N1     . DA  B 2 11 ? 20.70000  0.94900   -4.37700  1.000 43.16761  ?  11  DA  B N1     1 
ATOM   1878 C  C2     . DA  B 2 11 ? 20.54800  0.69600   -5.67800  1.000 47.50504  ?  11  DA  B C2     1 
ATOM   1879 N  N3     . DA  B 2 11 ? 19.50900  0.16600   -6.30800  1.000 53.35543  ?  11  DA  B N3     1 
ATOM   1880 C  C4     . DA  B 2 11 ? 18.53500  -0.13800  -5.43700  1.000 49.17709  ?  11  DA  B C4     1 
ATOM   1881 H  "H5'"  . DA  B 2 11 ? 13.55300  -0.01500  -8.86500  1.000 90.80329  ?  11  DA  B "H5'"  1 
ATOM   1882 H  "H5''" . DA  B 2 11 ? 13.52500  -1.46100  -9.51400  1.000 90.80329  ?  11  DA  B "H5''" 1 
ATOM   1883 H  "H4'"  . DA  B 2 11 ? 15.70700  -0.54200  -9.48400  1.000 80.23011  ?  11  DA  B "H4'"  1 
ATOM   1884 H  "H3'"  . DA  B 2 11 ? 15.23500  -3.07200  -8.78900  1.000 81.87514  ?  11  DA  B "H3'"  1 
ATOM   1885 H  "H2'"  . DA  B 2 11 ? 15.71800  -2.67100  -6.57600  1.000 75.46879  ?  11  DA  B "H2'"  1 
ATOM   1886 H  "H2''" . DA  B 2 11 ? 17.16400  -3.11800  -7.11600  1.000 75.46879  ?  11  DA  B "H2''" 1 
ATOM   1887 H  "H1'"  . DA  B 2 11 ? 17.67000  -0.92200  -7.66800  1.000 64.67561  ?  11  DA  B "H1'"  1 
ATOM   1888 H  H8     . DA  B 2 11 ? 15.80900  -1.18200  -4.43300  1.000 65.48550  ?  11  DA  B H8     1 
ATOM   1889 H  H61    . DA  B 2 11 ? 20.58000  1.22200   -1.93200  1.000 57.55180  ?  11  DA  B H61    1 
ATOM   1890 H  H62    . DA  B 2 11 ? 19.23000  0.65100   -1.67000  1.000 57.55180  ?  11  DA  B H62    1 
ATOM   1891 H  H2     . DA  B 2 11 ? 21.26400  0.93800   -6.22000  1.000 57.00604  ?  11  DA  B H2     1 
ATOM   1892 P  P      . DG  B 2 12 ? 17.65100  -4.01900  -9.80200  1.000 76.52810  ?  12  DG  B P      1 
ATOM   1893 O  OP1    . DG  B 2 12 ? 17.43200  -4.24600  -11.26400 1.000 66.11814  ?  12  DG  B OP1    1 
ATOM   1894 O  OP2    . DG  B 2 12 ? 17.14900  -4.93900  -8.75800  1.000 65.59772  -1 12  DG  B OP2    1 
ATOM   1895 O  "O5'"  . DG  B 2 12 ? 19.21400  -3.90200  -9.48900  1.000 71.29232  ?  12  DG  B "O5'"  1 
ATOM   1896 C  "C5'"  . DG  B 2 12 ? 20.03300  -2.92300  -10.13700 1.000 64.16336  ?  12  DG  B "C5'"  1 
ATOM   1897 C  "C4'"  . DG  B 2 12 ? 21.38100  -2.89300  -9.44600  1.000 65.10871  ?  12  DG  B "C4'"  1 
ATOM   1898 O  "O4'"  . DG  B 2 12 ? 21.20500  -2.42300  -8.07300  1.000 63.06152  ?  12  DG  B "O4'"  1 
ATOM   1899 C  "C3'"  . DG  B 2 12 ? 22.05100  -4.26800  -9.34600  1.000 65.57675  ?  12  DG  B "C3'"  1 
ATOM   1900 O  "O3'"  . DG  B 2 12 ? 23.34600  -4.25300  -9.98100  1.000 68.15035  ?  12  DG  B "O3'"  1 
ATOM   1901 C  "C2'"  . DG  B 2 12 ? 22.11800  -4.56900  -7.84100  1.000 61.47908  ?  12  DG  B "C2'"  1 
ATOM   1902 C  "C1'"  . DG  B 2 12 ? 21.99700  -3.19100  -7.19900  1.000 54.94430  ?  12  DG  B "C1'"  1 
ATOM   1903 N  N9     . DG  B 2 12 ? 21.36000  -3.13900  -5.87600  1.000 50.64227  ?  12  DG  B N9     1 
ATOM   1904 C  C8     . DG  B 2 12 ? 20.04500  -3.36600  -5.55800  1.000 52.91744  ?  12  DG  B C8     1 
ATOM   1905 N  N7     . DG  B 2 12 ? 19.77400  -3.18100  -4.29100  1.000 50.71596  ?  12  DG  B N7     1 
ATOM   1906 C  C5     . DG  B 2 12 ? 20.98800  -2.79500  -3.73800  1.000 46.24228  ?  12  DG  B C5     1 
ATOM   1907 C  C6     . DG  B 2 12 ? 21.32600  -2.44100  -2.39600  1.000 46.78202  ?  12  DG  B C6     1 
ATOM   1908 O  O6     . DG  B 2 12 ? 20.60300  -2.42200  -1.38400  1.000 47.62240  ?  12  DG  B O6     1 
ATOM   1909 N  N1     . DG  B 2 12 ? 22.67100  -2.09900  -2.28600  1.000 45.39264  ?  12  DG  B N1     1 
ATOM   1910 C  C2     . DG  B 2 12 ? 23.56400  -2.07700  -3.31900  1.000 42.95260  ?  12  DG  B C2     1 
ATOM   1911 N  N2     . DG  B 2 12 ? 24.81600  -1.71100  -3.02500  1.000 42.21078  ?  12  DG  B N2     1 
ATOM   1912 N  N3     . DG  B 2 12 ? 23.26000  -2.40100  -4.55400  1.000 47.12789  ?  12  DG  B N3     1 
ATOM   1913 C  C4     . DG  B 2 12 ? 21.96000  -2.73700  -4.69500  1.000 46.00417  ?  12  DG  B C4     1 
ATOM   1914 H  "H5'"  . DG  B 2 12 ? 19.61300  -2.05100  -10.07200 1.000 76.99603  ?  12  DG  B "H5'"  1 
ATOM   1915 H  "H5''" . DG  B 2 12 ? 20.15000  -3.16100  -11.07000 1.000 76.99603  ?  12  DG  B "H5''" 1 
ATOM   1916 H  "H4'"  . DG  B 2 12 ? 21.97000  -2.28400  -9.91900  1.000 78.13045  ?  12  DG  B "H4'"  1 
ATOM   1917 H  "H3'"  . DG  B 2 12 ? 21.49000  -4.93000  -9.78000  1.000 78.69210  ?  12  DG  B "H3'"  1 
ATOM   1918 H  "H2'"  . DG  B 2 12 ? 21.37800  -5.13700  -7.57300  1.000 73.77490  ?  12  DG  B "H2'"  1 
ATOM   1919 H  "H2''" . DG  B 2 12 ? 22.96600  -4.97900  -7.61200  1.000 73.77490  ?  12  DG  B "H2''" 1 
ATOM   1920 H  "H1'"  . DG  B 2 12 ? 22.87900  -2.79200  -7.14000  1.000 65.93316  ?  12  DG  B "H1'"  1 
ATOM   1921 H  H8     . DG  B 2 12 ? 19.41100  -3.64400  -6.17900  1.000 63.50092  ?  12  DG  B H8     1 
ATOM   1922 H  H1     . DG  B 2 12 ? 22.96000  -1.87500  -1.50800  1.000 54.47117  ?  12  DG  B H1     1 
ATOM   1923 H  H21    . DG  B 2 12 ? 25.41400  -1.68900  -3.64300  1.000 50.65294  ?  12  DG  B H21    1 
ATOM   1924 H  H22    . DG  B 2 12 ? 25.02300  -1.49700  -2.21800  1.000 50.65294  ?  12  DG  B H22    1 
ATOM   1925 P  P      . DT  B 2 13 ? 24.19500  -5.61600  -10.11400 1.000 76.91456  ?  13  DT  B P      1 
ATOM   1926 O  OP1    . DT  B 2 13 ? 25.11500  -5.50000  -11.27000 1.000 66.25323  ?  13  DT  B OP1    1 
ATOM   1927 O  OP2    . DT  B 2 13 ? 23.24200  -6.74100  -10.00700 1.000 76.12990  -1 13  DT  B OP2    1 
ATOM   1928 O  "O5'"  . DT  B 2 13 ? 25.05800  -5.68600  -8.76100  1.000 68.75916  ?  13  DT  B "O5'"  1 
ATOM   1929 C  "C5'"  . DT  B 2 13 ? 26.07200  -4.74200  -8.53600  1.000 68.33819  ?  13  DT  B "C5'"  1 
ATOM   1930 C  "C4'"  . DT  B 2 13 ? 26.82400  -5.04900  -7.26000  1.000 68.38676  ?  13  DT  B "C4'"  1 
ATOM   1931 O  "O4'"  . DT  B 2 13 ? 26.01500  -4.74500  -6.10100  1.000 64.82979  ?  13  DT  B "O4'"  1 
ATOM   1932 C  "C3'"  . DT  B 2 13 ? 27.22500  -6.50500  -7.12500  1.000 71.33493  ?  13  DT  B "C3'"  1 
ATOM   1933 O  "O3'"  . DT  B 2 13 ? 28.59700  -6.62100  -7.41200  1.000 75.82643  ?  13  DT  B "O3'"  1 
ATOM   1934 C  "C2'"  . DT  B 2 13 ? 26.86400  -6.89800  -5.67500  1.000 72.06416  ?  13  DT  B "C2'"  1 
ATOM   1935 C  "C1'"  . DT  B 2 13 ? 26.38300  -5.60100  -5.04000  1.000 62.25866  ?  13  DT  B "C1'"  1 
ATOM   1936 N  N1     . DT  B 2 13 ? 25.19800  -5.71000  -4.16600  1.000 57.64357  ?  13  DT  B N1     1 
ATOM   1937 C  C2     . DT  B 2 13 ? 25.30000  -5.38800  -2.82100  1.000 56.18729  ?  13  DT  B C2     1 
ATOM   1938 O  O2     . DT  B 2 13 ? 26.33300  -5.07100  -2.27400  1.000 56.19529  ?  13  DT  B O2     1 
ATOM   1939 N  N3     . DT  B 2 13 ? 24.14000  -5.47600  -2.12900  1.000 50.46631  ?  13  DT  B N3     1 
ATOM   1940 C  C4     . DT  B 2 13 ? 22.90500  -5.81900  -2.60900  1.000 46.56800  ?  13  DT  B C4     1 
ATOM   1941 O  O4     . DT  B 2 13 ? 21.91600  -5.85500  -1.88200  1.000 53.71411  ?  13  DT  B O4     1 
ATOM   1942 C  C5     . DT  B 2 13 ? 22.85200  -6.12700  -4.00800  1.000 50.37181  ?  13  DT  B C5     1 
ATOM   1943 C  C7     . DT  B 2 13 ? 21.57500  -6.50300  -4.63100  1.000 51.95338  ?  13  DT  B C7     1 
ATOM   1944 C  C6     . DT  B 2 13 ? 23.98400  -6.05300  -4.72100  1.000 55.75503  ?  13  DT  B C6     1 
ATOM   1945 H  "H5'"  . DT  B 2 13 ? 25.67600  -3.85900  -8.46800  1.000 82.00583  ?  13  DT  B "H5'"  1 
ATOM   1946 H  "H5''" . DT  B 2 13 ? 26.69200  -4.75600  -9.28200  1.000 82.00583  ?  13  DT  B "H5''" 1 
ATOM   1947 H  "H4'"  . DT  B 2 13 ? 27.62500  -4.50200  -7.23200  1.000 82.06411  ?  13  DT  B "H4'"  1 
ATOM   1948 H  "H3'"  . DT  B 2 13 ? 26.71400  -7.04500  -7.74700  1.000 85.60191  ?  13  DT  B "H3'"  1 
ATOM   1949 H  "H2'"  . DT  B 2 13 ? 26.15600  -7.56100  -5.67000  1.000 86.47699  ?  13  DT  B "H2'"  1 
ATOM   1950 H  "H2''" . DT  B 2 13 ? 27.64700  -7.23300  -5.21000  1.000 86.47699  ?  13  DT  B "H2''" 1 
ATOM   1951 H  "H1'"  . DT  B 2 13 ? 27.11200  -5.19800  -4.54300  1.000 74.71039  ?  13  DT  B "H1'"  1 
ATOM   1952 H  H3     . DT  B 2 13 ? 24.18400  -5.29300  -1.29000  1.000 60.55958  ?  13  DT  B H3     1 
ATOM   1953 H  H71    . DT  B 2 13 ? 21.38000  -5.89500  -5.36100  1.000 62.34406  ?  13  DT  B H71    1 
ATOM   1954 H  H72    . DT  B 2 13 ? 21.63600  -7.40900  -4.97200  1.000 62.34406  ?  13  DT  B H72    1 
ATOM   1955 H  H73    . DT  B 2 13 ? 20.86600  -6.45300  -3.97200  1.000 62.34406  ?  13  DT  B H73    1 
ATOM   1956 H  H6     . DT  B 2 13 ? 23.94800  -6.23900  -5.63200  1.000 66.90603  ?  13  DT  B H6     1 
ATOM   1957 P  P      . DG  B 2 14 ? 29.28900  -8.06700  -7.49900  1.000 87.84881  ?  14  DG  B P      1 
ATOM   1958 O  OP1    . DG  B 2 14 ? 30.49200  -7.81300  -8.33600  1.000 86.14055  -1 14  DG  B OP1    1 
ATOM   1959 O  OP2    . DG  B 2 14 ? 28.30700  -9.11700  -7.86100  1.000 78.93639  ?  14  DG  B OP2    1 
ATOM   1960 O  "O5'"  . DG  B 2 14 ? 29.78200  -8.31500  -6.00600  1.000 76.45415  ?  14  DG  B "O5'"  1 
ATOM   1961 C  "C5'"  . DG  B 2 14 ? 30.50300  -7.30200  -5.34800  1.000 77.91821  ?  14  DG  B "C5'"  1 
ATOM   1962 C  "C4'"  . DG  B 2 14 ? 30.70200  -7.62100  -3.88800  1.000 72.41054  ?  14  DG  B "C4'"  1 
ATOM   1963 O  "O4'"  . DG  B 2 14 ? 29.48800  -7.42700  -3.14400  1.000 68.21311  ?  14  DG  B "O4'"  1 
ATOM   1964 C  "C3'"  . DG  B 2 14 ? 31.12900  -9.06600  -3.58400  1.000 73.14811  ?  14  DG  B "C3'"  1 
ATOM   1965 O  "O3'"  . DG  B 2 14 ? 32.49000  -9.02700  -3.14500  1.000 79.74574  ?  14  DG  B "O3'"  1 
ATOM   1966 C  "C2'"  . DG  B 2 14 ? 30.11900  -9.54400  -2.51300  1.000 74.00532  ?  14  DG  B "C2'"  1 
ATOM   1967 C  "C1'"  . DG  B 2 14 ? 29.57400  -8.23000  -1.97700  1.000 75.44605  ?  14  DG  B "C1'"  1 
ATOM   1968 N  N9     . DG  B 2 14 ? 28.26500  -8.22800  -1.29800  1.000 68.75063  ?  14  DG  B N9     1 
ATOM   1969 C  C8     . DG  B 2 14 ? 28.00200  -7.73100  -0.00900  1.000 66.45343  ?  14  DG  B C8     1 
ATOM   1970 N  N7     . DG  B 2 14 ? 26.74300  -7.80300  0.34500   1.000 60.25585  ?  14  DG  B N7     1 
ATOM   1971 C  C5     . DG  B 2 14 ? 26.12600  -8.34700  -0.78400  1.000 62.15548  ?  14  DG  B C5     1 
ATOM   1972 C  C6     . DG  B 2 14 ? 24.78100  -8.64300  -0.99200  1.000 60.91859  ?  14  DG  B C6     1 
ATOM   1973 O  O6     . DG  B 2 14 ? 23.86500  -8.48200  -0.22200  1.000 65.39349  ?  14  DG  B O6     1 
ATOM   1974 N  N1     . DG  B 2 14 ? 24.53800  -9.21500  -2.24500  1.000 71.43989  ?  14  DG  B N1     1 
ATOM   1975 C  C2     . DG  B 2 14 ? 25.49400  -9.46100  -3.21900  1.000 69.85471  ?  14  DG  B C2     1 
ATOM   1976 N  N2     . DG  B 2 14 ? 25.02300  -10.03400 -4.37100  1.000 61.76291  ?  14  DG  B N2     1 
ATOM   1977 N  N3     . DG  B 2 14 ? 26.81300  -9.17200  -3.05100  1.000 66.72587  ?  14  DG  B N3     1 
ATOM   1978 C  C4     . DG  B 2 14 ? 27.04500  -8.61400  -1.80600  1.000 64.69292  ?  14  DG  B C4     1 
ATOM   1979 H  "H5'"  . DG  B 2 14 ? 30.01700  -6.46600  -5.42600  1.000 93.50185  ?  14  DG  B "H5'"  1 
ATOM   1980 H  "H5''" . DG  B 2 14 ? 31.37000  -7.20500  -5.77200  1.000 93.50185  ?  14  DG  B "H5''" 1 
ATOM   1981 H  "H4'"  . DG  B 2 14 ? 31.37700  -7.02200  -3.53400  1.000 86.89264  ?  14  DG  B "H4'"  1 
ATOM   1982 H  "H3'"  . DG  B 2 14 ? 31.05100  -9.61100  -4.38300  1.000 87.77773  ?  14  DG  B "H3'"  1 
ATOM   1983 H  "H2'"  . DG  B 2 14 ? 29.41200  -10.07000 -2.91800  1.000 88.80638  ?  14  DG  B "H2'"  1 
ATOM   1984 H  "H2''" . DG  B 2 14 ? 30.56700  -10.04200 -1.81400  1.000 88.80638  ?  14  DG  B "H2''" 1 
ATOM   1985 H  "H1'"  . DG  B 2 14 ? 30.23300  -7.84200  -1.38000  1.000 90.53526  ?  14  DG  B "H1'"  1 
ATOM   1986 H  H8     . DG  B 2 14 ? 28.66300  -7.37900  0.54200   1.000 79.74411  ?  14  DG  B H8     1 
ATOM   1987 H  H1     . DG  B 2 14 ? 23.72600  -9.43000  -2.42800  1.000 85.72786  ?  14  DG  B H1     1 
ATOM   1988 H  H21    . DG  B 2 14 ? 25.56600  -10.22000 -5.01200  1.000 74.11549  ?  14  DG  B H21    1 
ATOM   1989 H  H22    . DG  B 2 14 ? 24.18500  -10.20700 -4.45400  1.000 74.11549  ?  14  DG  B H22    1 
ATOM   1990 P  P      . DG  B 2 15 ? 33.35000  -10.35000 -2.86300  1.000 82.04892  ?  15  DG  B P      1 
ATOM   1991 O  OP1    . DG  B 2 15 ? 34.71500  -9.82400  -2.66300  1.000 71.99565  ?  15  DG  B OP1    1 
ATOM   1992 O  OP2    . DG  B 2 15 ? 33.10000  -11.37800 -3.90900  1.000 77.45827  -1 15  DG  B OP2    1 
ATOM   1993 O  "O5'"  . DG  B 2 15 ? 32.81800  -10.82600 -1.43100  1.000 79.33561  ?  15  DG  B "O5'"  1 
ATOM   1994 C  "C5'"  . DG  B 2 15 ? 32.92100  -9.90500  -0.33800  1.000 77.08446  ?  15  DG  B "C5'"  1 
ATOM   1995 C  "C4'"  . DG  B 2 15 ? 32.11200  -10.35100 0.85900   1.000 77.68399  ?  15  DG  B "C4'"  1 
ATOM   1996 O  "O4'"  . DG  B 2 15 ? 30.70000  -10.29200 0.54100   1.000 75.97120  ?  15  DG  B "O4'"  1 
ATOM   1997 C  "C3'"  . DG  B 2 15 ? 32.37400  -11.77700 1.33400   1.000 78.25947  ?  15  DG  B "C3'"  1 
ATOM   1998 O  "O3'"  . DG  B 2 15 ? 32.51400  -11.77000 2.74900   1.000 83.65211  ?  15  DG  B "O3'"  1 
ATOM   1999 C  "C2'"  . DG  B 2 15 ? 31.13900  -12.54800 0.85600   1.000 75.62166  ?  15  DG  B "C2'"  1 
ATOM   2000 C  "C1'"  . DG  B 2 15 ? 30.07100  -11.48300 0.96100   1.000 73.67498  ?  15  DG  B "C1'"  1 
ATOM   2001 N  N9     . DG  B 2 15 ? 28.85800  -11.67700 0.15800   1.000 72.65237  ?  15  DG  B N9     1 
ATOM   2002 C  C8     . DG  B 2 15 ? 28.73300  -12.05400 -1.17300  1.000 67.88805  ?  15  DG  B C8     1 
ATOM   2003 N  N7     . DG  B 2 15 ? 27.48400  -12.11300 -1.58400  1.000 68.32286  ?  15  DG  B N7     1 
ATOM   2004 C  C5     . DG  B 2 15 ? 26.74100  -11.74000 -0.43800  1.000 71.13370  ?  15  DG  B C5     1 
ATOM   2005 C  C6     . DG  B 2 15 ? 25.33100  -11.61900 -0.22700  1.000 69.02398  ?  15  DG  B C6     1 
ATOM   2006 O  O6     . DG  B 2 15 ? 24.41300  -11.80800 -1.02800  1.000 69.35574  ?  15  DG  B O6     1 
ATOM   2007 N  N1     . DG  B 2 15 ? 25.03200  -11.21600 1.07600   1.000 68.18041  ?  15  DG  B N1     1 
ATOM   2008 C  C2     . DG  B 2 15 ? 25.96900  -10.97200 2.05800   1.000 68.82993  ?  15  DG  B C2     1 
ATOM   2009 N  N2     . DG  B 2 15 ? 25.50400  -10.59700 3.26200   1.000 69.22141  ?  15  DG  B N2     1 
ATOM   2010 N  N3     . DG  B 2 15 ? 27.26700  -11.08300 1.87900   1.000 71.48929  ?  15  DG  B N3     1 
ATOM   2011 C  C4     . DG  B 2 15 ? 27.58200  -11.46800 0.61900   1.000 70.18054  ?  15  DG  B C4     1 
ATOM   2012 H  "H5'"  . DG  B 2 15 ? 32.60200  -9.03600  -0.62700  1.000 92.50135  ?  15  DG  B "H5'"  1 
ATOM   2013 H  "H5''" . DG  B 2 15 ? 33.85200  -9.82800  -0.07800  1.000 92.50135  ?  15  DG  B "H5''" 1 
ATOM   2014 H  "H4'"  . DG  B 2 15 ? 32.28900  -9.74400  1.59400   1.000 93.22079  ?  15  DG  B "H4'"  1 
ATOM   2015 H  "H3'"  . DG  B 2 15 ? 33.17500  -12.12900 0.91600   1.000 93.91136  ?  15  DG  B "H3'"  1 
ATOM   2016 H  "H2'"  . DG  B 2 15 ? 31.24700  -12.84300 -0.06200  1.000 90.74600  ?  15  DG  B "H2'"  1 
ATOM   2017 H  "H2''" . DG  B 2 15 ? 30.94600  -13.29400 1.44500   1.000 90.74600  ?  15  DG  B "H2''" 1 
ATOM   2018 H  "H1'"  . DG  B 2 15 ? 29.81600  -11.38900 1.89200   1.000 88.40997  ?  15  DG  B "H1'"  1 
ATOM   2019 H  H8     . DG  B 2 15 ? 29.46000  -12.24800 -1.71900  1.000 81.46566  ?  15  DG  B H8     1 
ATOM   2020 H  H1     . DG  B 2 15 ? 24.20300  -11.11800 1.28300   1.000 81.81649  ?  15  DG  B H1     1 
ATOM   2021 H  H21    . DG  B 2 15 ? 26.05300  -10.43400 3.90300   1.000 83.06569  ?  15  DG  B H21    1 
ATOM   2022 H  H22    . DG  B 2 15 ? 24.65700  -10.52000 3.39100   1.000 83.06569  ?  15  DG  B H22    1 
ATOM   2023 P  P      . DG  B 2 16 ? 33.58600  -12.71100 3.48500   1.000 90.55645  ?  16  DG  B P      1 
ATOM   2024 O  OP1    . DG  B 2 16 ? 34.57200  -11.81900 4.14600   1.000 87.13662  ?  16  DG  B OP1    1 
ATOM   2025 O  OP2    . DG  B 2 16 ? 34.07000  -13.72100 2.50800   1.000 85.69208  -1 16  DG  B OP2    1 
ATOM   2026 O  "O5'"  . DG  B 2 16 ? 32.70100  -13.44700 4.60100   1.000 82.79890  ?  16  DG  B "O5'"  1 
ATOM   2027 C  "C5'"  . DG  B 2 16 ? 32.07400  -12.67600 5.63000   1.000 85.39982  ?  16  DG  B "C5'"  1 
ATOM   2028 C  "C4'"  . DG  B 2 16 ? 30.73700  -13.27800 6.05000   1.000 83.57135  ?  16  DG  B "C4'"  1 
ATOM   2029 O  "O4'"  . DG  B 2 16 ? 29.77800  -13.13200 4.97600   1.000 81.03762  ?  16  DG  B "O4'"  1 
ATOM   2030 C  "C3'"  . DG  B 2 16 ? 30.78200  -14.77300 6.37200   1.000 84.67351  ?  16  DG  B "C3'"  1 
ATOM   2031 O  "O3'"  . DG  B 2 16 ? 30.66100  -14.97900 7.78100   1.000 91.35517  ?  16  DG  B "O3'"  1 
ATOM   2032 C  "C2'"  . DG  B 2 16 ? 29.60900  -15.38800 5.59600   1.000 79.31176  ?  16  DG  B "C2'"  1 
ATOM   2033 C  "C1'"  . DG  B 2 16 ? 28.84100  -14.17000 5.07400   1.000 80.17486  ?  16  DG  B "C1'"  1 
ATOM   2034 N  N9     . DG  B 2 16 ? 28.22900  -14.37800 3.77300   1.000 74.11544  ?  16  DG  B N9     1 
ATOM   2035 C  C8     . DG  B 2 16 ? 28.86500  -14.70600 2.59900   1.000 75.90433  ?  16  DG  B C8     1 
ATOM   2036 N  N7     . DG  B 2 16 ? 28.05000  -14.83400 1.58500   1.000 74.57263  ?  16  DG  B N7     1 
ATOM   2037 C  C5     . DG  B 2 16 ? 26.79000  -14.57400 2.13200   1.000 71.36353  ?  16  DG  B C5     1 
ATOM   2038 C  C6     . DG  B 2 16 ? 25.50700  -14.56400 1.52500   1.000 70.08064  ?  16  DG  B C6     1 
ATOM   2039 O  O6     . DG  B 2 16 ? 25.20900  -14.77900 0.34400   1.000 67.01530  ?  16  DG  B O6     1 
ATOM   2040 N  N1     . DG  B 2 16 ? 24.50900  -14.25100 2.44100   1.000 70.90727  ?  16  DG  B N1     1 
ATOM   2041 C  C2     . DG  B 2 16 ? 24.72000  -13.98100 3.76800   1.000 74.63311  ?  16  DG  B C2     1 
ATOM   2042 N  N2     . DG  B 2 16 ? 23.62900  -13.70600 4.49700   1.000 77.52812  ?  16  DG  B N2     1 
ATOM   2043 N  N3     . DG  B 2 16 ? 25.90900  -13.98900 4.34500   1.000 73.25459  ?  16  DG  B N3     1 
ATOM   2044 C  C4     . DG  B 2 16 ? 26.89300  -14.28700 3.47300   1.000 70.41185  ?  16  DG  B C4     1 
ATOM   2045 H  "H5'"  . DG  B 2 16 ? 31.92600  -11.77400 5.30400   1.000 102.47979 ?  16  DG  B "H5'"  1 
ATOM   2046 H  "H5''" . DG  B 2 16 ? 32.66100  -12.64100 6.40100   1.000 102.47979 ?  16  DG  B "H5''" 1 
ATOM   2047 H  "H4'"  . DG  B 2 16 ? 30.41000  -12.80000 6.82800   1.000 100.28562 ?  16  DG  B "H4'"  1 
ATOM   2048 H  "H3'"  . DG  B 2 16 ? 31.61800  -15.15100 6.05600   1.000 101.60822 ?  16  DG  B "H3'"  1 
ATOM   2049 H  "HO3'" . DG  B 2 16 ? 30.02200  -15.43000 8.08600   1.000 109.62621 ?  16  DG  B "HO3'" 1 
ATOM   2050 H  "H2'"  . DG  B 2 16 ? 29.93400  -15.92800 4.85900   1.000 95.17411  ?  16  DG  B "H2'"  1 
ATOM   2051 H  "H2''" . DG  B 2 16 ? 29.04900  -15.91600 6.18700   1.000 95.17411  ?  16  DG  B "H2''" 1 
ATOM   2052 H  "H1'"  . DG  B 2 16 ? 28.15600  -13.92400 5.71500   1.000 96.20983  ?  16  DG  B "H1'"  1 
ATOM   2053 H  H8     . DG  B 2 16 ? 29.78500  -14.82400 2.53200   1.000 91.08520  ?  16  DG  B H8     1 
ATOM   2054 H  H1     . DG  B 2 16 ? 23.70000  -14.21900 2.15200   1.000 85.08872  ?  16  DG  B H1     1 
ATOM   2055 H  H21    . DG  B 2 16 ? 23.70500  -13.53600 5.33700   1.000 93.03374  ?  16  DG  B H21    1 
ATOM   2056 H  H22    . DG  B 2 16 ? 22.85400  -13.70000 4.12500   1.000 93.03374  ?  16  DG  B H22    1 
ATOM   2057 N  N      . LYS C 1 5  ? 0.70400   -3.94900  19.85000  1.000 53.44250  ?  169 LYS C N      1 
ATOM   2058 C  CA     . LYS C 1 5  ? -0.09400  -2.76700  20.12500  1.000 65.65770  ?  169 LYS C CA     1 
ATOM   2059 C  C      . LYS C 1 5  ? 0.07400   -1.71900  19.00500  1.000 60.77966  ?  169 LYS C C      1 
ATOM   2060 O  O      . LYS C 1 5  ? 0.65300   -1.98500  17.93900  1.000 61.69160  ?  169 LYS C O      1 
ATOM   2061 C  CB     . LYS C 1 5  ? 0.27100   -2.15100  21.50300  1.000 56.73363  ?  169 LYS C CB     1 
ATOM   2062 H  HA     . LYS C 1 5  ? -1.02900  -3.02200  20.15400  1.000 78.78924  ?  169 LYS C HA     1 
ATOM   2063 N  N      . ILE C 1 6  ? -0.48500  -0.53800  19.26500  1.000 58.53820  ?  170 ILE C N      1 
ATOM   2064 C  CA     . ILE C 1 6  ? -0.60000  0.54400   18.29900  1.000 56.92426  ?  170 ILE C CA     1 
ATOM   2065 C  C      . ILE C 1 6  ? 0.58900   1.47600   18.48800  1.000 51.14653  ?  170 ILE C C      1 
ATOM   2066 O  O      . ILE C 1 6  ? 1.09600   1.64000   19.61000  1.000 53.05584  ?  170 ILE C O      1 
ATOM   2067 C  CB     . ILE C 1 6  ? -1.95100  1.28300   18.44800  1.000 52.26852  ?  170 ILE C CB     1 
ATOM   2068 C  CG1    . ILE C 1 6  ? -1.97000  2.56600   17.61400  1.000 51.80429  ?  170 ILE C CG1    1 
ATOM   2069 C  CG2    . ILE C 1 6  ? -2.23100  1.63800   19.89900  1.000 59.15956  ?  170 ILE C CG2    1 
ATOM   2070 C  CD1    . ILE C 1 6  ? -3.36300  3.05200   17.24900  1.000 49.53813  ?  170 ILE C CD1    1 
ATOM   2071 H  H      . ILE C 1 6  ? -0.81200  -0.33900  20.03400  1.000 70.24584  ?  170 ILE C H      1 
ATOM   2072 H  HA     . ILE C 1 6  ? -0.55500  0.17600   17.40300  1.000 68.30911  ?  170 ILE C HA     1 
ATOM   2073 H  HB     . ILE C 1 6  ? -2.65800  0.69900   18.13200  1.000 62.72222  ?  170 ILE C HB     1 
ATOM   2074 H  HG12   . ILE C 1 6  ? -1.53400  3.27100   18.11700  1.000 62.16515  ?  170 ILE C HG12   1 
ATOM   2075 H  HG13   . ILE C 1 6  ? -1.48800  2.40700   16.78700  1.000 62.16515  ?  170 ILE C HG13   1 
ATOM   2076 H  HG21   . ILE C 1 6  ? -2.96000  2.27700   19.93100  1.000 70.99147  ?  170 ILE C HG21   1 
ATOM   2077 H  HG22   . ILE C 1 6  ? -2.47800  0.83300   20.38100  1.000 70.99147  ?  170 ILE C HG22   1 
ATOM   2078 H  HG23   . ILE C 1 6  ? -1.43400  2.02900   20.28900  1.000 70.99147  ?  170 ILE C HG23   1 
ATOM   2079 H  HD11   . ILE C 1 6  ? -3.28500  3.84600   16.69800  1.000 59.44576  ?  170 ILE C HD11   1 
ATOM   2080 H  HD12   . ILE C 1 6  ? -3.82200  2.35200   16.75900  1.000 59.44576  ?  170 ILE C HD12   1 
ATOM   2081 H  HD13   . ILE C 1 6  ? -3.84900  3.26000   18.06200  1.000 59.44576  ?  170 ILE C HD13   1 
ATOM   2082 N  N      . ARG C 1 7  ? 1.05800   2.07200   17.38700  1.000 46.25246  ?  171 ARG C N      1 
ATOM   2083 C  CA     . ARG C 1 7  ? 2.20400   2.96200   17.43200  1.000 44.85646  ?  171 ARG C CA     1 
ATOM   2084 C  C      . ARG C 1 7  ? 1.77900   4.40900   17.67000  1.000 39.25006  ?  171 ARG C C      1 
ATOM   2085 O  O      . ARG C 1 7  ? 0.70500   4.84600   17.23000  1.000 38.07400  ?  171 ARG C O      1 
ATOM   2086 C  CB     . ARG C 1 7  ? 3.00500   2.84000   16.13900  1.000 46.64128  ?  171 ARG C CB     1 
ATOM   2087 C  CG     . ARG C 1 7  ? 3.55200   1.42500   15.96200  1.000 48.65909  ?  171 ARG C CG     1 
ATOM   2088 C  CD     . ARG C 1 7  ? 4.38800   1.28000   14.73200  1.000 55.80202  ?  171 ARG C CD     1 
ATOM   2089 N  NE     . ARG C 1 7  ? 5.60900   2.08600   14.79800  1.000 60.93953  ?  171 ARG C NE     1 
ATOM   2090 C  CZ     . ARG C 1 7  ? 6.84100   1.60300   14.69100  1.000 57.06338  ?  171 ARG C CZ     1 
ATOM   2091 N  NH1    . ARG C 1 7  ? 7.05900   0.31200   14.45400  1.000 62.86298  ?  171 ARG C NH1    1 
ATOM   2092 N  NH2    . ARG C 1 7  ? 7.88200   2.43700   14.80600  1.000 50.86446  ?  171 ARG C NH2    1 
ATOM   2093 H  H      . ARG C 1 7  ? 0.72300   1.97200   16.60100  1.000 55.50295  ?  171 ARG C H      1 
ATOM   2094 H  HA     . ARG C 1 7  ? 2.78100   2.69600   18.16500  1.000 53.82775  ?  171 ARG C HA     1 
ATOM   2095 H  HB2    . ARG C 1 7  ? 2.43000   3.04100   15.38400  1.000 55.96954  ?  171 ARG C HB2    1 
ATOM   2096 H  HB3    . ARG C 1 7  ? 3.75400   3.45600   16.16600  1.000 55.96954  ?  171 ARG C HB3    1 
ATOM   2097 H  HG2    . ARG C 1 7  ? 4.10300   1.20100   16.72800  1.000 58.39091  ?  171 ARG C HG2    1 
ATOM   2098 H  HG3    . ARG C 1 7  ? 2.81000   0.80400   15.89400  1.000 58.39091  ?  171 ARG C HG3    1 
ATOM   2099 H  HD2    . ARG C 1 7  ? 4.62600   0.34800   14.62600  1.000 66.96242  ?  171 ARG C HD2    1 
ATOM   2100 H  HD3    . ARG C 1 7  ? 3.87400   1.57900   13.96600  1.000 66.96242  ?  171 ARG C HD3    1 
ATOM   2101 H  HE     . ARG C 1 7  ? 5.52200   2.93200   14.92800  1.000 73.12744  ?  171 ARG C HE     1 
ATOM   2102 H  HH11   . ARG C 1 7  ? 6.40600   -0.23900  14.37500  1.000 75.43557  ?  171 ARG C HH11   1 
ATOM   2103 H  HH12   . ARG C 1 7  ? 7.86600   0.02500   14.38500  1.000 75.43557  ?  171 ARG C HH12   1 
ATOM   2104 H  HH21   . ARG C 1 7  ? 7.74800   3.27300   14.95600  1.000 61.03735  ?  171 ARG C HH21   1 
ATOM   2105 H  HH22   . ARG C 1 7  ? 8.68400   2.13600   14.73300  1.000 61.03735  ?  171 ARG C HH22   1 
ATOM   2106 N  N      . LEU C 1 8  ? 2.64400   5.15600   18.38100  1.000 37.65755  ?  172 LEU C N      1 
ATOM   2107 C  CA     . LEU C 1 8  ? 2.37100   6.56800   18.64300  1.000 37.01605  ?  172 LEU C CA     1 
ATOM   2108 C  C      . LEU C 1 8  ? 2.01500   7.37800   17.36400  1.000 36.66579  ?  172 LEU C C      1 
ATOM   2109 O  O      . LEU C 1 8  ? 1.04400   8.15600   17.37100  1.000 30.67309  ?  172 LEU C O      1 
ATOM   2110 C  CB     . LEU C 1 8  ? 3.54100   7.19000   19.38200  1.000 33.45600  ?  172 LEU C CB     1 
ATOM   2111 C  CG     . LEU C 1 8  ? 3.41200   8.68900   19.59700  1.000 35.69213  ?  172 LEU C CG     1 
ATOM   2112 C  CD1    . LEU C 1 8  ? 2.14000   9.01700   20.40800  1.000 33.07507  ?  172 LEU C CD1    1 
ATOM   2113 C  CD2    . LEU C 1 8  ? 4.59400   9.18300   20.35000  1.000 35.33058  ?  172 LEU C CD2    1 
ATOM   2114 H  H      . LEU C 1 8  ? 3.38200   4.86800   18.71500  1.000 45.18906  ?  172 LEU C H      1 
ATOM   2115 H  HA     . LEU C 1 8  ? 1.60200   6.61600   19.23200  1.000 44.41926  ?  172 LEU C HA     1 
ATOM   2116 H  HB2    . LEU C 1 8  ? 3.61700   6.77200   20.25400  1.000 40.14720  ?  172 LEU C HB2    1 
ATOM   2117 H  HB3    . LEU C 1 8  ? 4.35100   7.03300   18.87200  1.000 40.14720  ?  172 LEU C HB3    1 
ATOM   2118 H  HG     . LEU C 1 8  ? 3.37300   9.15200   18.74600  1.000 42.83056  ?  172 LEU C HG     1 
ATOM   2119 H  HD11   . LEU C 1 8  ? 2.14200   9.96200   20.62600  1.000 39.69008  ?  172 LEU C HD11   1 
ATOM   2120 H  HD12   . LEU C 1 8  ? 1.35900   8.80300   19.87500  1.000 39.69008  ?  172 LEU C HD12   1 
ATOM   2121 H  HD13   . LEU C 1 8  ? 2.14100   8.49100   21.22200  1.000 39.69008  ?  172 LEU C HD13   1 
ATOM   2122 H  HD21   . LEU C 1 8  ? 4.50800   10.14000  20.48000  1.000 42.39669  ?  172 LEU C HD21   1 
ATOM   2123 H  HD22   . LEU C 1 8  ? 4.63100   8.73400   21.20900  1.000 42.39669  ?  172 LEU C HD22   1 
ATOM   2124 H  HD23   . LEU C 1 8  ? 5.39600   8.98900   19.84000  1.000 42.39669  ?  172 LEU C HD23   1 
ATOM   2125 N  N      . TYR C 1 9  ? 2.79400   7.25400   16.26300  1.000 37.31725  ?  173 TYR C N      1 
ATOM   2126 C  CA     . TYR C 1 9  ? 2.45900   8.10100   15.09700  1.000 33.44768  ?  173 TYR C CA     1 
ATOM   2127 C  C      . TYR C 1 9  ? 1.09300   7.75200   14.51800  1.000 34.14458  ?  173 TYR C C      1 
ATOM   2128 O  O      . TYR C 1 9  ? 0.35100   8.63400   14.06600  1.000 33.38603  ?  173 TYR C O      1 
ATOM   2129 C  CB     . TYR C 1 9  ? 3.53600   8.01600   14.00200  1.000 39.60564  ?  173 TYR C CB     1 
ATOM   2130 C  CG     . TYR C 1 9  ? 3.64700   6.69700   13.27400  1.000 38.47887  ?  173 TYR C CG     1 
ATOM   2131 C  CD1    . TYR C 1 9  ? 2.77300   6.38700   12.26500  1.000 43.02381  ?  173 TYR C CD1    1 
ATOM   2132 C  CD2    . TYR C 1 9  ? 4.65800   5.78900   13.57400  1.000 40.94436  ?  173 TYR C CD2    1 
ATOM   2133 C  CE1    . TYR C 1 9  ? 2.85500   5.19800   11.57100  1.000 54.21698  ?  173 TYR C CE1    1 
ATOM   2134 C  CE2    . TYR C 1 9  ? 4.75700   4.56700   12.87400  1.000 46.23407  ?  173 TYR C CE2    1 
ATOM   2135 C  CZ     . TYR C 1 9  ? 3.85000   4.29900   11.87100  1.000 53.13728  ?  173 TYR C CZ     1 
ATOM   2136 O  OH     . TYR C 1 9  ? 3.89500   3.13000   11.15000  1.000 56.20925  ?  173 TYR C OH     1 
ATOM   2137 H  H      . TYR C 1 9  ? 3.46900   6.72900   16.17000  1.000 44.78070  ?  173 TYR C H      1 
ATOM   2138 H  HA     . TYR C 1 9  ? 2.42000   9.02400   15.39300  1.000 40.13722  ?  173 TYR C HA     1 
ATOM   2139 H  HB2    . TYR C 1 9  ? 3.34800   8.69700   13.33700  1.000 47.52677  ?  173 TYR C HB2    1 
ATOM   2140 H  HB3    . TYR C 1 9  ? 4.39800   8.19400   14.40900  1.000 47.52677  ?  173 TYR C HB3    1 
ATOM   2141 H  HD1    . TYR C 1 9  ? 2.09800   6.98900   12.05100  1.000 51.62858  ?  173 TYR C HD1    1 
ATOM   2142 H  HD2    . TYR C 1 9  ? 5.26600   5.98300   14.25000  1.000 49.13323  ?  173 TYR C HD2    1 
ATOM   2143 H  HE1    . TYR C 1 9  ? 2.24600   5.01000   10.89400  1.000 65.06038  ?  173 TYR C HE1    1 
ATOM   2144 H  HE2    . TYR C 1 9  ? 5.43000   3.95800   13.07800  1.000 55.48088  ?  173 TYR C HE2    1 
ATOM   2145 H  HH     . TYR C 1 9  ? 4.53700   2.65500   11.41200  1.000 67.45111  ?  173 TYR C HH     1 
ATOM   2146 N  N      . GLN C 1 10 ? 0.72300   6.48500   14.57800  1.000 37.90762  ?  174 GLN C N      1 
ATOM   2147 C  CA     . GLN C 1 10 ? -0.56800  6.08400   14.04900  1.000 40.90789  ?  174 GLN C CA     1 
ATOM   2148 C  C      . GLN C 1 10 ? -1.69500  6.61000   14.91500  1.000 36.85666  ?  174 GLN C C      1 
ATOM   2149 O  O      . GLN C 1 10 ? -2.72400  7.03000   14.40700  1.000 34.88601  ?  174 GLN C O      1 
ATOM   2150 C  CB     . GLN C 1 10 ? -0.63900  4.56700   13.95400  1.000 41.85754  ?  174 GLN C CB     1 
ATOM   2151 C  CG     . GLN C 1 10 ? -1.88800  4.07100   13.23100  1.000 49.93924  ?  174 GLN C CG     1 
ATOM   2152 C  CD     . GLN C 1 10 ? -1.99600  4.58300   11.77300  1.000 53.29347  ?  174 GLN C CD     1 
ATOM   2153 O  OE1    . GLN C 1 10 ? -3.01700  5.15000   11.37500  1.000 53.58722  ?  174 GLN C OE1    1 
ATOM   2154 N  NE2    . GLN C 1 10 ? -0.94400  4.38500   10.99300  1.000 56.88146  ?  174 GLN C NE2    1 
ATOM   2155 H  H      . GLN C 1 10 ? 1.19100   5.84700   14.91400  1.000 45.48915  ?  174 GLN C H      1 
ATOM   2156 H  HA     . GLN C 1 10 ? -0.67300  6.45300   13.15800  1.000 49.08947  ?  174 GLN C HA     1 
ATOM   2157 H  HB2    . GLN C 1 10 ? 0.13600   4.24600   13.46700  1.000 50.22905  ?  174 GLN C HB2    1 
ATOM   2158 H  HB3    . GLN C 1 10 ? -0.64500  4.19500   14.85000  1.000 50.22905  ?  174 GLN C HB3    1 
ATOM   2159 H  HG2    . GLN C 1 10 ? -1.87000  3.10200   13.20500  1.000 59.92708  ?  174 GLN C HG2    1 
ATOM   2160 H  HG3    . GLN C 1 10 ? -2.67400  4.37200   13.71300  1.000 59.92708  ?  174 GLN C HG3    1 
ATOM   2161 H  HE21   . GLN C 1 10 ? -0.24800  3.98700   11.30300  1.000 68.25775  ?  174 GLN C HE21   1 
ATOM   2162 H  HE22   . GLN C 1 10 ? -0.95800  4.65300   10.17600  1.000 68.25775  ?  174 GLN C HE22   1 
ATOM   2163 N  N      . PHE C 1 11 ? -1.50200  6.57900   16.22600  1.000 37.21269  ?  175 PHE C N      1 
ATOM   2164 C  CA     . PHE C 1 11 ? -2.46500  7.15900   17.16600  1.000 34.01022  ?  175 PHE C CA     1 
ATOM   2165 C  C      . PHE C 1 11 ? -2.70200  8.62400   16.82000  1.000 34.62732  ?  175 PHE C C      1 
ATOM   2166 O  O      . PHE C 1 11 ? -3.84800  9.10100   16.76200  1.000 36.47205  ?  175 PHE C O      1 
ATOM   2167 C  CB     . PHE C 1 11 ? -1.91800  6.98500   18.60000  1.000 34.71831  ?  175 PHE C CB     1 
ATOM   2168 C  CG     . PHE C 1 11 ? -2.63000  7.77800   19.62500  1.000 33.76454  ?  175 PHE C CG     1 
ATOM   2169 C  CD1    . PHE C 1 11 ? -3.86100  7.36500   20.08700  1.000 39.28540  ?  175 PHE C CD1    1 
ATOM   2170 C  CD2    . PHE C 1 11 ? -2.09200  8.93700   20.12100  1.000 40.20539  ?  175 PHE C CD2    1 
ATOM   2171 C  CE1    . PHE C 1 11 ? -4.55100  8.09700   21.02500  1.000 35.61894  ?  175 PHE C CE1    1 
ATOM   2172 C  CE2    . PHE C 1 11 ? -2.77900  9.67900   21.13300  1.000 37.09342  ?  175 PHE C CE2    1 
ATOM   2173 C  CZ     . PHE C 1 11 ? -3.99500  9.25300   21.56700  1.000 36.32153  ?  175 PHE C CZ     1 
ATOM   2174 H  H      . PHE C 1 11 ? -0.81600  6.22500   16.60500  1.000 44.65523  ?  175 PHE C H      1 
ATOM   2175 H  HA     . PHE C 1 11 ? -3.30900  6.68600   17.09900  1.000 40.81226  ?  175 PHE C HA     1 
ATOM   2176 H  HB2    . PHE C 1 11 ? -1.99000  6.05000   18.84800  1.000 41.66197  ?  175 PHE C HB2    1 
ATOM   2177 H  HB3    . PHE C 1 11 ? -0.98700  7.25600   18.61200  1.000 41.66197  ?  175 PHE C HB3    1 
ATOM   2178 H  HD1    . PHE C 1 11 ? -4.24100  6.58900   19.74300  1.000 47.14248  ?  175 PHE C HD1    1 
ATOM   2179 H  HD2    . PHE C 1 11 ? -1.25400  9.21800   19.83100  1.000 48.24647  ?  175 PHE C HD2    1 
ATOM   2180 H  HE1    . PHE C 1 11 ? -5.37500  7.79400   21.33100  1.000 42.74273  ?  175 PHE C HE1    1 
ATOM   2181 H  HE2    . PHE C 1 11 ? -2.41100  10.46400  21.46900  1.000 44.51211  ?  175 PHE C HE2    1 
ATOM   2182 H  HZ     . PHE C 1 11 ? -4.46200  9.74200   22.20500  1.000 43.58584  ?  175 PHE C HZ     1 
ATOM   2183 N  N      . LEU C 1 12 ? -1.60700  9.36400   16.56600  1.000 32.80614  ?  176 LEU C N      1 
ATOM   2184 C  CA     . LEU C 1 12 ? -1.79300  10.79200  16.33100  1.000 28.84526  ?  176 LEU C CA     1 
ATOM   2185 C  C      . LEU C 1 12 ? -2.49500  11.01100  14.99000  1.000 35.18776  ?  176 LEU C C      1 
ATOM   2186 O  O      . LEU C 1 12 ? -3.34700  11.90600  14.84200  1.000 34.70684  ?  176 LEU C O      1 
ATOM   2187 C  CB     . LEU C 1 12 ? -0.44100  11.50100  16.35900  1.000 26.15229  ?  176 LEU C CB     1 
ATOM   2188 C  CG     . LEU C 1 12 ? 0.40500   11.44100  17.64100  1.000 30.13990  ?  176 LEU C CG     1 
ATOM   2189 C  CD1    . LEU C 1 12 ? 1.74600   12.10600  17.49600  1.000 27.90381  ?  176 LEU C CD1    1 
ATOM   2190 C  CD2    . LEU C 1 12 ? -0.36800  12.17900  18.64200  1.000 32.89873  ?  176 LEU C CD2    1 
ATOM   2191 H  H      . LEU C 1 12 ? -0.79700  9.07800   16.52700  1.000 39.36737  ?  176 LEU C H      1 
ATOM   2192 H  HA     . LEU C 1 12 ? -2.35300  11.16400  17.03000  1.000 34.61431  ?  176 LEU C HA     1 
ATOM   2193 H  HB2    . LEU C 1 12 ? 0.10300   11.12100  15.65100  1.000 31.38275  ?  176 LEU C HB2    1 
ATOM   2194 H  HB3    . LEU C 1 12 ? -0.59500  12.43900  16.16400  1.000 31.38275  ?  176 LEU C HB3    1 
ATOM   2195 H  HG     . LEU C 1 12 ? 0.52300   10.52400  17.93300  1.000 36.16788  ?  176 LEU C HG     1 
ATOM   2196 H  HD11   . LEU C 1 12 ? 2.23100   12.02400  18.33200  1.000 33.48457  ?  176 LEU C HD11   1 
ATOM   2197 H  HD12   . LEU C 1 12 ? 2.23800   11.67000  16.78300  1.000 33.48457  ?  176 LEU C HD12   1 
ATOM   2198 H  HD13   . LEU C 1 12 ? 1.61200   13.04200  17.28200  1.000 33.48457  ?  176 LEU C HD13   1 
ATOM   2199 H  HD21   . LEU C 1 12 ? 0.17300   12.28400  19.44000  1.000 39.47848  ?  176 LEU C HD21   1 
ATOM   2200 H  HD22   . LEU C 1 12 ? -0.60100  13.05100  18.28700  1.000 39.47848  ?  176 LEU C HD22   1 
ATOM   2201 H  HD23   . LEU C 1 12 ? -1.17300  11.68100  18.85300  1.000 39.47848  ?  176 LEU C HD23   1 
ATOM   2202 N  N      . LEU C 1 13 ? -2.09300  10.23600  13.99200  1.000 38.42641  ?  177 LEU C N      1 
ATOM   2203 C  CA     . LEU C 1 13 ? -2.69800  10.35800  12.66900  1.000 33.74847  ?  177 LEU C CA     1 
ATOM   2204 C  C      . LEU C 1 13 ? -4.18700  10.05300  12.71300  1.000 37.64672  ?  177 LEU C C      1 
ATOM   2205 O  O      . LEU C 1 13 ? -4.99100  10.73300  12.06100  1.000 38.42661  ?  177 LEU C O      1 
ATOM   2206 C  CB     . LEU C 1 13 ? -1.98600  9.40700   11.71600  1.000 37.69276  ?  177 LEU C CB     1 
ATOM   2207 C  CG     . LEU C 1 13 ? -2.33100  9.54800   10.23300  1.000 44.49712  ?  177 LEU C CG     1 
ATOM   2208 C  CD1    . LEU C 1 13 ? -1.94200  10.91900  9.73700   1.000 40.64894  ?  177 LEU C CD1    1 
ATOM   2209 C  CD2    . LEU C 1 13 ? -1.63600  8.40700   9.47000   1.000 46.50436  ?  177 LEU C CD2    1 
ATOM   2210 H  H      . LEU C 1 13 ? -1.47900  9.63700   14.05100  1.000 46.11169  ?  177 LEU C H      1 
ATOM   2211 H  HA     . LEU C 1 13 ? -2.58100  11.26500  12.34800  1.000 40.49817  ?  177 LEU C HA     1 
ATOM   2212 H  HB2    . LEU C 1 13 ? -1.03000  9.54800   11.80400  1.000 45.23131  ?  177 LEU C HB2    1 
ATOM   2213 H  HB3    . LEU C 1 13 ? -2.20200  8.49800   11.97700  1.000 45.23131  ?  177 LEU C HB3    1 
ATOM   2214 H  HG     . LEU C 1 13 ? -3.28900  9.44700   10.11900  1.000 53.39654  ?  177 LEU C HG     1 
ATOM   2215 H  HD11   . LEU C 1 13 ? -2.00500  10.93200  8.76900   1.000 48.77873  ?  177 LEU C HD11   1 
ATOM   2216 H  HD12   . LEU C 1 13 ? -2.54500  11.57700  10.11600  1.000 48.77873  ?  177 LEU C HD12   1 
ATOM   2217 H  HD13   . LEU C 1 13 ? -1.03000  11.10700  10.01100  1.000 48.77873  ?  177 LEU C HD13   1 
ATOM   2218 H  HD21   . LEU C 1 13 ? -1.84300  8.48700   8.52600   1.000 55.80523  ?  177 LEU C HD21   1 
ATOM   2219 H  HD22   . LEU C 1 13 ? -0.67800  8.47400   9.60600   1.000 55.80523  ?  177 LEU C HD22   1 
ATOM   2220 H  HD23   . LEU C 1 13 ? -1.96000  7.55800   9.80900   1.000 55.80523  ?  177 LEU C HD23   1 
ATOM   2221 N  N      . ASP C 1 14 ? -4.57400  9.01500   13.45600  1.000 38.75739  ?  178 ASP C N      1 
ATOM   2222 C  CA     . ASP C 1 14 ? -5.98200  8.64600   13.54300  1.000 40.37163  ?  178 ASP C CA     1 
ATOM   2223 C  C      . ASP C 1 14 ? -6.81600  9.73100   14.20800  1.000 43.72431  ?  178 ASP C C      1 
ATOM   2224 O  O      . ASP C 1 14 ? -7.97500  9.95400   13.82200  1.000 39.30305  ?  178 ASP C O      1 
ATOM   2225 C  CB     . ASP C 1 14 ? -6.10900  7.33800   14.30500  1.000 39.69212  ?  178 ASP C CB     1 
ATOM   2226 C  CG     . ASP C 1 14 ? -5.60100  6.17400   13.50000  1.000 45.77133  ?  178 ASP C CG     1 
ATOM   2227 O  OD1    . ASP C 1 14 ? -5.22500  6.42000   12.33000  1.000 49.76124  ?  178 ASP C OD1    1 
ATOM   2228 O  OD2    . ASP C 1 14 ? -5.56300  5.01900   14.01000  1.000 59.99713  -1 178 ASP C OD2    1 
ATOM   2229 H  H      . ASP C 1 14 ? -4.04500  8.51500   13.91400  1.000 46.50887  ?  178 ASP C H      1 
ATOM   2230 H  HA     . ASP C 1 14 ? -6.33100  8.51100   12.64800  1.000 48.44595  ?  178 ASP C HA     1 
ATOM   2231 H  HB2    . ASP C 1 14 ? -5.58800  7.39200   15.12200  1.000 47.63054  ?  178 ASP C HB2    1 
ATOM   2232 H  HB3    . ASP C 1 14 ? -7.04300  7.17900   14.51300  1.000 47.63054  ?  178 ASP C HB3    1 
ATOM   2233 N  N      . LEU C 1 15 ? -6.23500  10.44600  15.17500  1.000 33.17462  ?  179 LEU C N      1 
ATOM   2234 C  CA     . LEU C 1 15 ? -6.96900  11.59600  15.74700  1.000 34.38666  ?  179 LEU C CA     1 
ATOM   2235 C  C      . LEU C 1 15 ? -7.17500  12.67400  14.69100  1.000 39.31918  ?  179 LEU C C      1 
ATOM   2236 O  O      . LEU C 1 15 ? -8.23300  13.34200  14.62800  1.000 36.11112  ?  179 LEU C O      1 
ATOM   2237 C  CB     . LEU C 1 15 ? -6.18700  12.19500  16.92600  1.000 31.40018  ?  179 LEU C CB     1 
ATOM   2238 C  CG     . LEU C 1 15 ? -6.17900  11.41700  18.25000  1.000 36.12120  ?  179 LEU C CG     1 
ATOM   2239 C  CD1    . LEU C 1 15 ? -4.99000  11.82600  19.21400  1.000 37.64778  ?  179 LEU C CD1    1 
ATOM   2240 C  CD2    . LEU C 1 15 ? -7.53300  11.60700  18.97100  1.000 39.72373  ?  179 LEU C CD2    1 
ATOM   2241 H  H      . LEU C 1 15 ? -5.45500  10.30200  15.50800  1.000 39.80954  ?  179 LEU C H      1 
ATOM   2242 H  HA     . LEU C 1 15 ? -7.83700  11.30400  16.06600  1.000 41.26399  ?  179 LEU C HA     1 
ATOM   2243 H  HB2    . LEU C 1 15 ? -5.26200  12.29400  16.65100  1.000 37.68021  ?  179 LEU C HB2    1 
ATOM   2244 H  HB3    . LEU C 1 15 ? -6.55700  13.07200  17.11500  1.000 37.68021  ?  179 LEU C HB3    1 
ATOM   2245 H  HG     . LEU C 1 15 ? -6.08300  10.47200  18.05200  1.000 43.34544  ?  179 LEU C HG     1 
ATOM   2246 H  HD11   . LEU C 1 15 ? -5.07900  11.33900  20.04800  1.000 45.17734  ?  179 LEU C HD11   1 
ATOM   2247 H  HD12   . LEU C 1 15 ? -4.14700  11.60300  18.78800  1.000 45.17734  ?  179 LEU C HD12   1 
ATOM   2248 H  HD13   . LEU C 1 15 ? -5.03500  12.78000  19.38200  1.000 45.17734  ?  179 LEU C HD13   1 
ATOM   2249 H  HD21   . LEU C 1 15 ? -7.49700  11.16400  19.83300  1.000 47.66847  ?  179 LEU C HD21   1 
ATOM   2250 H  HD22   . LEU C 1 15 ? -7.69400  12.55600  19.09300  1.000 47.66847  ?  179 LEU C HD22   1 
ATOM   2251 H  HD23   . LEU C 1 15 ? -8.23600  11.21800  18.42800  1.000 47.66847  ?  179 LEU C HD23   1 
ATOM   2252 N  N      . LEU C 1 16 ? -6.12400  12.89400  13.87900  1.000 37.00241  ?  180 LEU C N      1 
ATOM   2253 C  CA     . LEU C 1 16 ? -6.16400  14.00800  12.94200  1.000 38.09815  ?  180 LEU C CA     1 
ATOM   2254 C  C      . LEU C 1 16 ? -7.14600  13.72500  11.80600  1.000 37.44403  ?  180 LEU C C      1 
ATOM   2255 O  O      . LEU C 1 16 ? -7.97900  14.57000  11.46700  1.000 38.75870  ?  180 LEU C O      1 
ATOM   2256 C  CB     . LEU C 1 16 ? -4.75600  14.27100  12.43300  1.000 36.13274  ?  180 LEU C CB     1 
ATOM   2257 C  CG     . LEU C 1 16 ? -3.88700  15.03800  13.42100  1.000 40.81171  ?  180 LEU C CG     1 
ATOM   2258 C  CD1    . LEU C 1 16 ? -2.43600  14.74800  13.18000  1.000 34.17624  ?  180 LEU C CD1    1 
ATOM   2259 C  CD2    . LEU C 1 16 ? -4.15000  16.54100  13.40300  1.000 39.13758  ?  180 LEU C CD2    1 
ATOM   2260 H  H      . LEU C 1 16 ? -5.40400  12.42400  13.85800  1.000 44.40289  ?  180 LEU C H      1 
ATOM   2261 H  HA     . LEU C 1 16 ? -6.46700  14.80200  13.40900  1.000 45.71778  ?  180 LEU C HA     1 
ATOM   2262 H  HB2    . LEU C 1 16 ? -4.32400  13.42200  12.25300  1.000 43.35929  ?  180 LEU C HB2    1 
ATOM   2263 H  HB3    . LEU C 1 16 ? -4.81000  14.79300  11.61700  1.000 43.35929  ?  180 LEU C HB3    1 
ATOM   2264 H  HG     . LEU C 1 16 ? -4.09700  14.72300  14.31400  1.000 48.97406  ?  180 LEU C HG     1 
ATOM   2265 H  HD11   . LEU C 1 16 ? -1.90300  15.26200  13.80700  1.000 41.01149  ?  180 LEU C HD11   1 
ATOM   2266 H  HD12   . LEU C 1 16 ? -2.27800  13.80000  13.31000  1.000 41.01149  ?  180 LEU C HD12   1 
ATOM   2267 H  HD13   . LEU C 1 16 ? -2.21100  15.00000  12.27100  1.000 41.01149  ?  180 LEU C HD13   1 
ATOM   2268 H  HD21   . LEU C 1 16 ? -3.53100  16.97700  14.00900  1.000 46.96510  ?  180 LEU C HD21   1 
ATOM   2269 H  HD22   . LEU C 1 16 ? -4.01900  16.87300  12.50100  1.000 46.96510  ?  180 LEU C HD22   1 
ATOM   2270 H  HD23   . LEU C 1 16 ? -5.06300  16.70500  13.68700  1.000 46.96510  ?  180 LEU C HD23   1 
ATOM   2271 N  N      . ARG C 1 17 ? -7.09600  12.51400  11.27300  1.000 32.44864  ?  181 ARG C N      1 
ATOM   2272 C  CA     . ARG C 1 17 ? -7.95100  12.10300  10.18100  1.000 43.38426  ?  181 ARG C CA     1 
ATOM   2273 C  C      . ARG C 1 17 ? -9.38800  11.90600  10.59600  1.000 47.13737  ?  181 ARG C C      1 
ATOM   2274 O  O      . ARG C 1 17 ? -10.25500 12.00200  9.72700   1.000 53.12687  ?  181 ARG C O      1 
ATOM   2275 C  CB     . ARG C 1 17 ? -7.39500  10.82500  9.53200   1.000 50.21686  ?  181 ARG C CB     1 
ATOM   2276 C  CG     . ARG C 1 17 ? -6.05200  11.08400  8.83200   1.000 45.87342  ?  181 ARG C CG     1 
ATOM   2277 C  CD     . ARG C 1 17 ? -5.51400  9.90100   8.03000   1.000 53.72587  ?  181 ARG C CD     1 
ATOM   2278 N  NE     . ARG C 1 17 ? -4.55900  10.34800  7.01600   1.000 51.97842  ?  181 ARG C NE     1 
ATOM   2279 C  CZ     . ARG C 1 17 ? -3.69400  9.55900   6.38800   1.000 63.37319  ?  181 ARG C CZ     1 
ATOM   2280 N  NH1    . ARG C 1 17 ? -3.67100  8.24100   6.59300   1.000 61.69495  ?  181 ARG C NH1    1 
ATOM   2281 N  NH2    . ARG C 1 17 ? -2.81600  10.10600  5.53700   1.000 66.51214  ?  181 ARG C NH2    1 
ATOM   2282 H  H      . ARG C 1 17 ? -6.55800  11.89700  11.53700  1.000 38.93837  ?  181 ARG C H      1 
ATOM   2283 H  HA     . ARG C 1 17 ? -7.93900  12.79900  9.50600   1.000 52.06111  ?  181 ARG C HA     1 
ATOM   2284 H  HB2    . ARG C 1 17 ? -7.25600  10.15300  10.21700  1.000 60.26023  ?  181 ARG C HB2    1 
ATOM   2285 H  HB3    . ARG C 1 17 ? -8.02600  10.50300  8.86900   1.000 60.26023  ?  181 ARG C HB3    1 
ATOM   2286 H  HG2    . ARG C 1 17 ? -6.16000  11.82900  8.22000   1.000 55.04810  ?  181 ARG C HG2    1 
ATOM   2287 H  HG3    . ARG C 1 17 ? -5.39000  11.30800  9.50500   1.000 55.04810  ?  181 ARG C HG3    1 
ATOM   2288 H  HD2    . ARG C 1 17 ? -5.06100  9.28600   8.62800   1.000 64.47105  ?  181 ARG C HD2    1 
ATOM   2289 H  HD3    . ARG C 1 17 ? -6.25000  9.45500   7.58200   1.000 64.47105  ?  181 ARG C HD3    1 
ATOM   2290 H  HE     . ARG C 1 17 ? -4.55700  11.18300  6.81100   1.000 62.37411  ?  181 ARG C HE     1 
ATOM   2291 H  HH11   . ARG C 1 17 ? -4.22700  7.88000   7.14000   1.000 74.03394  ?  181 ARG C HH11   1 
ATOM   2292 H  HH12   . ARG C 1 17 ? -3.10100  7.75100   6.17400   1.000 74.03394  ?  181 ARG C HH12   1 
ATOM   2293 H  HH21   . ARG C 1 17 ? -2.82400  10.95500  5.39800   1.000 79.81456  ?  181 ARG C HH21   1 
ATOM   2294 H  HH22   . ARG C 1 17 ? -2.25200  9.60700   5.12100   1.000 79.81456  ?  181 ARG C HH22   1 
ATOM   2295 N  N      . SER C 1 18 ? -9.67900  11.66700  11.88600  1.000 42.96095  ?  182 SER C N      1 
ATOM   2296 C  CA     . SER C 1 18 ? -11.06400 11.61300  12.31500  1.000 41.54681  ?  182 SER C CA     1 
ATOM   2297 C  C      . SER C 1 18 ? -11.57100 12.91700  12.92400  1.000 42.64481  ?  182 SER C C      1 
ATOM   2298 O  O      . SER C 1 18 ? -12.74100 12.99200  13.30900  1.000 47.09553  ?  182 SER C O      1 
ATOM   2299 C  CB     . SER C 1 18 ? -11.27900 10.41500  13.27500  1.000 47.45749  ?  182 SER C CB     1 
ATOM   2300 O  OG     . SER C 1 18 ? -10.49900 10.41800  14.46300  1.000 42.83024  ?  182 SER C OG     1 
ATOM   2301 H  H      . SER C 1 18 ? -9.10100  11.53700  12.50900  1.000 51.55314  ?  182 SER C H      1 
ATOM   2302 H  HA     . SER C 1 18 ? -11.61400 11.44100  11.53500  1.000 49.85617  ?  182 SER C HA     1 
ATOM   2303 H  HB2    . SER C 1 18 ? -12.21400 10.40300  13.53200  1.000 56.94899  ?  182 SER C HB2    1 
ATOM   2304 H  HB3    . SER C 1 18 ? -11.07600 9.60200   12.78700  1.000 56.94899  ?  182 SER C HB3    1 
ATOM   2305 H  HG     . SER C 1 18 ? -9.68200  10.41200  14.27000  1.000 51.39628  ?  182 SER C HG     1 
ATOM   2306 N  N      . GLY C 1 19 ? -10.72900 13.92300  13.02800  1.000 42.27217  ?  183 GLY C N      1 
ATOM   2307 C  CA     . GLY C 1 19 ? -11.13600 15.18700  13.64700  1.000 47.20879  ?  183 GLY C CA     1 
ATOM   2308 C  C      . GLY C 1 19 ? -11.51400 15.03500  15.10800  1.000 47.26311  ?  183 GLY C C      1 
ATOM   2309 O  O      . GLY C 1 19 ? -12.57000 15.51000  15.49400  1.000 48.45680  ?  183 GLY C O      1 
ATOM   2310 H  H      . GLY C 1 19 ? -9.91500  13.91100  12.75200  1.000 50.72660  ?  183 GLY C H      1 
ATOM   2311 H  HA2    . GLY C 1 19 ? -10.40800 15.82400  13.58200  1.000 56.65055  ?  183 GLY C HA2    1 
ATOM   2312 H  HA3    . GLY C 1 19 ? -11.90100 15.54400  13.16900  1.000 56.65055  ?  183 GLY C HA3    1 
ATOM   2313 N  N      . ASP C 1 20 ? -10.75800 14.29500  15.90500  1.000 43.54842  ?  184 ASP C N      1 
ATOM   2314 C  CA     . ASP C 1 20 ? -10.99100 14.23600  17.36400  1.000 41.91608  ?  184 ASP C CA     1 
ATOM   2315 C  C      . ASP C 1 20 ? -9.94100  15.13000  18.00600  1.000 43.79478  ?  184 ASP C C      1 
ATOM   2316 O  O      . ASP C 1 20 ? -8.91100  15.35900  17.37700  1.000 39.84310  ?  184 ASP C O      1 
ATOM   2317 C  CB     . ASP C 1 20 ? -10.95800 12.81600  17.92000  1.000 49.11777  ?  184 ASP C CB     1 
ATOM   2318 C  CG     . ASP C 1 20 ? -11.90900 12.51100  19.06500  1.000 48.56177  ?  184 ASP C CG     1 
ATOM   2319 O  OD1    . ASP C 1 20 ? -12.47600 13.44500  19.66600  1.000 59.40976  ?  184 ASP C OD1    1 
ATOM   2320 O  OD2    . ASP C 1 20 ? -12.07500 11.32100  19.34900  1.000 57.71703  -1 184 ASP C OD2    1 
ATOM   2321 H  H      . ASP C 1 20 ? -10.09900 13.81200  15.63600  1.000 52.25810  ?  184 ASP C H      1 
ATOM   2322 H  HA     . ASP C 1 20 ? -11.86300 14.61100  17.56300  1.000 50.29930  ?  184 ASP C HA     1 
ATOM   2323 H  HB2    . ASP C 1 20 ? -11.17100 12.20300  17.19900  1.000 58.94133  ?  184 ASP C HB2    1 
ATOM   2324 H  HB3    . ASP C 1 20 ? -10.06000 12.63700  18.23800  1.000 58.94133  ?  184 ASP C HB3    1 
ATOM   2325 N  N      . MET C 1 21 ? -10.22700 15.63200  19.19800  1.000 46.19108  ?  185 MET C N      1 
ATOM   2326 C  CA     . MET C 1 21 ? -9.27700  16.45100  19.97800  1.000 41.54534  ?  185 MET C CA     1 
ATOM   2327 C  C      . MET C 1 21 ? -8.74100  17.56300  19.08900  1.000 44.91541  ?  185 MET C C      1 
ATOM   2328 O  O      . MET C 1 21 ? -7.57100  17.58700  18.88700  1.000 47.35118  ?  185 MET C O      1 
ATOM   2329 C  CB     . MET C 1 21 ? -8.14900  15.56100  20.49400  1.000 38.32983  ?  185 MET C CB     1 
ATOM   2330 C  CG     . MET C 1 21 ? -8.66900  14.36000  21.24400  1.000 51.85350  ?  185 MET C CG     1 
ATOM   2331 S  SD     . MET C 1 21 ? -7.42600  13.60800  22.29300  1.000 46.58158  ?  185 MET C SD     1 
ATOM   2332 C  CE     . MET C 1 21 ? -7.20500  14.89800  23.51200  1.000 49.30863  ?  185 MET C CE     1 
ATOM   2333 H  H      . MET C 1 21 ? -10.98100 15.51500  19.59500  1.000 55.42930  ?  185 MET C H      1 
ATOM   2334 H  HA     . MET C 1 21 ? -9.73500  16.83900  20.74000  1.000 49.85441  ?  185 MET C HA     1 
ATOM   2335 H  HB2    . MET C 1 21 ? -7.62400  15.24300  19.74200  1.000 45.99580  ?  185 MET C HB2    1 
ATOM   2336 H  HB3    . MET C 1 21 ? -7.59200  16.07400  21.09700  1.000 45.99580  ?  185 MET C HB3    1 
ATOM   2337 H  HG2    . MET C 1 21 ? -9.40900  14.63600  21.80700  1.000 62.22420  ?  185 MET C HG2    1 
ATOM   2338 H  HG3    . MET C 1 21 ? -8.96800  13.69300  20.60600  1.000 62.22420  ?  185 MET C HG3    1 
ATOM   2339 H  HE1    . MET C 1 21 ? -6.86100  14.50500  24.32900  1.000 59.17035  ?  185 MET C HE1    1 
ATOM   2340 H  HE2    . MET C 1 21 ? -6.57800  15.55400  23.16900  1.000 59.17035  ?  185 MET C HE2    1 
ATOM   2341 H  HE3    . MET C 1 21 ? -8.06300  15.31600  23.68600  1.000 59.17035  ?  185 MET C HE3    1 
ATOM   2342 N  N      . LYS C 1 22 ? -9.60200  18.41900  18.56900  1.000 38.22749  ?  186 LYS C N      1 
ATOM   2343 C  CA     . LYS C 1 22 ? -9.16500  19.55800  17.73800  1.000 46.44149  ?  186 LYS C CA     1 
ATOM   2344 C  C      . LYS C 1 22 ? -8.61800  20.63500  18.67000  1.000 48.41090  ?  186 LYS C C      1 
ATOM   2345 O  O      . LYS C 1 22 ? -7.81100  21.41500  18.21000  1.000 45.49130  ?  186 LYS C O      1 
ATOM   2346 C  CB     . LYS C 1 22 ? -10.29800 20.09800  16.87000  1.000 56.09639  ?  186 LYS C CB     1 
ATOM   2347 C  CG     . LYS C 1 22 ? -11.05400 19.06300  16.05300  1.000 63.70341  ?  186 LYS C CG     1 
ATOM   2348 C  CD     . LYS C 1 22 ? -10.30300 18.61000  14.83700  1.000 71.58154  ?  186 LYS C CD     1 
ATOM   2349 C  CE     . LYS C 1 22 ? -11.00800 18.97900  13.55300  1.000 67.38472  ?  186 LYS C CE     1 
ATOM   2350 N  NZ     . LYS C 1 22 ? -12.30600 18.27700  13.42400  1.000 73.57082  ?  186 LYS C NZ     1 
ATOM   2351 H  H      . LYS C 1 22 ? -10.45400 18.37300  18.67600  1.000 45.87299  ?  186 LYS C H      1 
ATOM   2352 H  HA     . LYS C 1 22 ? -8.44700  19.27000  17.15300  1.000 55.72979  ?  186 LYS C HA     1 
ATOM   2353 H  HB2    . LYS C 1 22 ? -10.94200 20.53700  17.44700  1.000 67.31567  ?  186 LYS C HB2    1 
ATOM   2354 H  HB3    . LYS C 1 22 ? -9.92700  20.74500  16.25000  1.000 67.31567  ?  186 LYS C HB3    1 
ATOM   2355 H  HG2    . LYS C 1 22 ? -11.22600 18.28500  16.60500  1.000 76.44409  ?  186 LYS C HG2    1 
ATOM   2356 H  HG3    . LYS C 1 22 ? -11.89300 19.44900  15.75700  1.000 76.44409  ?  186 LYS C HG3    1 
ATOM   2357 H  HD2    . LYS C 1 22 ? -9.42700  19.02700  14.83000  1.000 85.89785  ?  186 LYS C HD2    1 
ATOM   2358 H  HD3    . LYS C 1 22 ? -10.21100 17.64500  14.86500  1.000 85.89785  ?  186 LYS C HD3    1 
ATOM   2359 H  HE2    . LYS C 1 22 ? -11.17700 19.93400  13.54400  1.000 80.86166  ?  186 LYS C HE2    1 
ATOM   2360 H  HE3    . LYS C 1 22 ? -10.45100 18.72900  12.79900  1.000 80.86166  ?  186 LYS C HE3    1 
ATOM   2361 H  HZ1    . LYS C 1 22 ? -12.51800 18.18300  12.56500  1.000 88.28498  ?  186 LYS C HZ1    1 
ATOM   2362 H  HZ2    . LYS C 1 22 ? -12.25500 17.47300  13.80100  1.000 88.28498  ?  186 LYS C HZ2    1 
ATOM   2363 H  HZ3    . LYS C 1 22 ? -12.94500 18.74400  13.83200  1.000 88.28498  ?  186 LYS C HZ3    1 
ATOM   2364 N  N      . ASP C 1 23 ? -9.05100  20.68600  19.93200  1.000 46.34316  ?  187 ASP C N      1 
ATOM   2365 C  CA     . ASP C 1 23 ? -8.49000  21.63200  20.88000  1.000 49.77788  ?  187 ASP C CA     1 
ATOM   2366 C  C      . ASP C 1 23 ? -7.07000  21.26300  21.25900  1.000 43.35431  ?  187 ASP C C      1 
ATOM   2367 O  O      . ASP C 1 23 ? -6.32500  22.12400  21.72100  1.000 44.50031  ?  187 ASP C O      1 
ATOM   2368 C  CB     . ASP C 1 23 ? -9.34800  21.69300  22.15900  1.000 64.91668  ?  187 ASP C CB     1 
ATOM   2369 C  CG     . ASP C 1 23 ? -10.75300 22.25000  21.91200  1.000 79.24869  ?  187 ASP C CG     1 
ATOM   2370 O  OD1    . ASP C 1 23 ? -10.88800 23.48700  21.74100  1.000 88.18511  ?  187 ASP C OD1    1 
ATOM   2371 O  OD2    . ASP C 1 23 ? -11.71700 21.44900  21.85800  1.000 99.23787  -1 187 ASP C OD2    1 
ATOM   2372 H  H      . ASP C 1 23 ? -9.66800  20.18300  20.25800  1.000 55.61179  ?  187 ASP C H      1 
ATOM   2373 H  HA     . ASP C 1 23 ? -8.47800  22.51600  20.48000  1.000 59.73345  ?  187 ASP C HA     1 
ATOM   2374 H  HB2    . ASP C 1 23 ? -9.44100  20.79700  22.51900  1.000 77.90001  ?  187 ASP C HB2    1 
ATOM   2375 H  HB3    . ASP C 1 23 ? -8.90800  22.26600  22.80600  1.000 77.90001  ?  187 ASP C HB3    1 
ATOM   2376 N  N      . SER C 1 24 ? -6.70200  20.00000  21.10100  1.000 39.72030  ?  188 SER C N      1 
ATOM   2377 C  CA     . SER C 1 24 ? -5.38700  19.49000  21.46500  1.000 46.18312  ?  188 SER C CA     1 
ATOM   2378 C  C      . SER C 1 24 ? -4.41800  19.33300  20.27600  1.000 38.38638  ?  188 SER C C      1 
ATOM   2379 O  O      . SER C 1 24 ? -3.21700  19.49900  20.44200  1.000 34.50474  ?  188 SER C O      1 
ATOM   2380 C  CB     . SER C 1 24 ? -5.53400  18.12600  22.17300  1.000 41.26510  ?  188 SER C CB     1 
ATOM   2381 O  OG     . SER C 1 24 ? -6.06900  18.25200  23.46200  1.000 43.92134  ?  188 SER C OG     1 
ATOM   2382 H  H      . SER C 1 24 ? -7.21700  19.39400  20.77300  1.000 47.66436  ?  188 SER C H      1 
ATOM   2383 H  HA     . SER C 1 24 ? -4.98000  20.10500  22.09500  1.000 55.41974  ?  188 SER C HA     1 
ATOM   2384 H  HB2    . SER C 1 24 ? -6.12000  17.56500  21.64400  1.000 49.51812  ?  188 SER C HB2    1 
ATOM   2385 H  HB3    . SER C 1 24 ? -4.65800  17.71500  22.23800  1.000 49.51812  ?  188 SER C HB3    1 
ATOM   2386 H  HG     . SER C 1 24 ? -5.56300  18.72400  23.93800  1.000 52.70561  ?  188 SER C HG     1 
ATOM   2387 N  N      . ILE C 1 25 ? -4.87400  18.94100  19.10000  1.000 35.62564  ?  189 ILE C N      1 
ATOM   2388 C  CA     . ILE C 1 25 ? -3.96900  18.70100  17.96100  1.000 38.93698  ?  189 ILE C CA     1 
ATOM   2389 C  C      . ILE C 1 25 ? -4.68500  19.09100  16.66600  1.000 38.35691  ?  189 ILE C C      1 
ATOM   2390 O  O      . ILE C 1 25 ? -5.90600  18.92400  16.56400  1.000 38.68270  ?  189 ILE C O      1 
ATOM   2391 C  CB     . ILE C 1 25 ? -3.54400  17.22600  17.93900  1.000 37.09270  ?  189 ILE C CB     1 
ATOM   2392 C  CG1    . ILE C 1 25 ? -2.38200  17.05500  16.98900  1.000 37.29941  ?  189 ILE C CG1    1 
ATOM   2393 C  CG2    . ILE C 1 25 ? -4.74700  16.34400  17.59400  1.000 38.74857  ?  189 ILE C CG2    1 
ATOM   2394 C  CD1    . ILE C 1 25 ? -1.80900  15.61800  16.93600  1.000 36.36763  ?  189 ILE C CD1    1 
ATOM   2395 H  H      . ILE C 1 25 ? -5.70400  18.80300  18.92300  1.000 42.75077  ?  189 ILE C H      1 
ATOM   2396 H  HA     . ILE C 1 25 ? -3.17500  19.25100  18.05100  1.000 46.72438  ?  189 ILE C HA     1 
ATOM   2397 H  HB     . ILE C 1 25 ? -3.24200  16.98700  18.82900  1.000 44.51124  ?  189 ILE C HB     1 
ATOM   2398 H  HG12   . ILE C 1 25 ? -2.67300  17.28900  16.09400  1.000 44.75929  ?  189 ILE C HG12   1 
ATOM   2399 H  HG13   . ILE C 1 25 ? -1.66500  17.64800  17.26500  1.000 44.75929  ?  189 ILE C HG13   1 
ATOM   2400 H  HG21   . ILE C 1 25 ? -4.53000  15.42200  17.80200  1.000 46.49828  ?  189 ILE C HG21   1 
ATOM   2401 H  HG22   . ILE C 1 25 ? -5.50900  16.62900  18.12000  1.000 46.49828  ?  189 ILE C HG22   1 
ATOM   2402 H  HG23   . ILE C 1 25 ? -4.94600  16.43000  16.64900  1.000 46.49828  ?  189 ILE C HG23   1 
ATOM   2403 H  HD11   . ILE C 1 25 ? -1.04000  15.60700  16.34500  1.000 43.64115  ?  189 ILE C HD11   1 
ATOM   2404 H  HD12   . ILE C 1 25 ? -1.54300  15.35100  17.83000  1.000 43.64115  ?  189 ILE C HD12   1 
ATOM   2405 H  HD13   . ILE C 1 25 ? -2.49300  15.01700  16.60100  1.000 43.64115  ?  189 ILE C HD13   1 
ATOM   2406 N  N      . TRP C 1 26 ? -3.94700  19.65700  15.69500  1.000 34.11505  ?  190 TRP C N      1 
ATOM   2407 C  CA     . TRP C 1 26 ? -4.58400  20.10800  14.44600  1.000 40.42187  ?  190 TRP C CA     1 
ATOM   2408 C  C      . TRP C 1 26 ? -3.57300  20.18800  13.29900  1.000 39.88666  ?  190 TRP C C      1 
ATOM   2409 O  O      . TRP C 1 26 ? -2.37600  20.41800  13.52900  1.000 33.72559  ?  190 TRP C O      1 
ATOM   2410 C  CB     . TRP C 1 26 ? -5.27500  21.47500  14.60100  1.000 39.54055  ?  190 TRP C CB     1 
ATOM   2411 C  CG     . TRP C 1 26 ? -4.35700  22.54000  15.06300  1.000 42.23133  ?  190 TRP C CG     1 
ATOM   2412 C  CD1    . TRP C 1 26 ? -3.39200  23.21300  14.31800  1.000 45.96563  ?  190 TRP C CD1    1 
ATOM   2413 C  CD2    . TRP C 1 26 ? -4.27200  23.06200  16.40000  1.000 44.95012  ?  190 TRP C CD2    1 
ATOM   2414 N  NE1    . TRP C 1 26 ? -2.72800  24.11700  15.13100  1.000 47.34190  ?  190 TRP C NE1    1 
ATOM   2415 C  CE2    . TRP C 1 26 ? -3.24400  24.03500  16.41100  1.000 47.61257  ?  190 TRP C CE2    1 
ATOM   2416 C  CE3    . TRP C 1 26 ? -4.95000  22.78100  17.58800  1.000 46.59280  ?  190 TRP C CE3    1 
ATOM   2417 C  CZ2    . TRP C 1 26 ? -2.90500  24.74100  17.57100  1.000 44.82982  ?  190 TRP C CZ2    1 
ATOM   2418 C  CZ3    . TRP C 1 26 ? -4.62300  23.48000  18.72700  1.000 48.06874  ?  190 TRP C CZ3    1 
ATOM   2419 C  CH2    . TRP C 1 26 ? -3.60500  24.44800  18.71000  1.000 47.73418  ?  190 TRP C CH2    1 
ATOM   2420 H  H      . TRP C 1 26 ? -3.09800  19.78800  15.73300  1.000 40.93806  ?  190 TRP C H      1 
ATOM   2421 H  HA     . TRP C 1 26 ? -5.26300  19.46300  14.19400  1.000 48.50625  ?  190 TRP C HA     1 
ATOM   2422 H  HB2    . TRP C 1 26 ? -5.63700  21.74400  13.74200  1.000 47.44866  ?  190 TRP C HB2    1 
ATOM   2423 H  HB3    . TRP C 1 26 ? -5.99100  21.39400  15.25100  1.000 47.44866  ?  190 TRP C HB3    1 
ATOM   2424 H  HD1    . TRP C 1 26 ? -3.22000  23.07600  13.41400  1.000 55.15876  ?  190 TRP C HD1    1 
ATOM   2425 H  HE1    . TRP C 1 26 ? -2.09500  24.64300  14.88100  1.000 56.81028  ?  190 TRP C HE1    1 
ATOM   2426 H  HE3    . TRP C 1 26 ? -5.62400  22.14100  17.60500  1.000 55.91136  ?  190 TRP C HE3    1 
ATOM   2427 H  HZ2    . TRP C 1 26 ? -2.23700  25.38800  17.56600  1.000 53.79578  ?  190 TRP C HZ2    1 
ATOM   2428 H  HZ3    . TRP C 1 26 ? -5.07400  23.30100  19.52000  1.000 57.68248  ?  190 TRP C HZ3    1 
ATOM   2429 H  HH2    . TRP C 1 26 ? -3.40200  24.90300  19.49500  1.000 57.28102  ?  190 TRP C HH2    1 
ATOM   2430 N  N      . TRP C 1 27 ? -4.06200  19.97800  12.07600  1.000 39.61071  ?  191 TRP C N      1 
ATOM   2431 C  CA     . TRP C 1 27 ? -3.23600  20.10700  10.85900  1.000 37.28580  ?  191 TRP C CA     1 
ATOM   2432 C  C      . TRP C 1 27 ? -2.87100  21.57800  10.68200  1.000 37.18279  ?  191 TRP C C      1 
ATOM   2433 O  O      . TRP C 1 27 ? -3.76100  22.40100  10.86500  1.000 43.48825  ?  191 TRP C O      1 
ATOM   2434 C  CB     . TRP C 1 27 ? -3.98400  19.58900  9.62800   1.000 38.11453  ?  191 TRP C CB     1 
ATOM   2435 C  CG     . TRP C 1 27 ? -4.16500  18.11200  9.48500   1.000 35.02834  ?  191 TRP C CG     1 
ATOM   2436 C  CD1    . TRP C 1 27 ? -5.35200  17.45300  9.38800   1.000 32.75853  ?  191 TRP C CD1    1 
ATOM   2437 C  CD2    . TRP C 1 27 ? -3.14100  17.11700  9.33300   1.000 35.44409  ?  191 TRP C CD2    1 
ATOM   2438 N  NE1    . TRP C 1 27 ? -5.14100  16.11400  9.22600   1.000 40.63841  ?  191 TRP C NE1    1 
ATOM   2439 C  CE2    . TRP C 1 27 ? -3.79500  15.87700  9.18700   1.000 33.30916  ?  191 TRP C CE2    1 
ATOM   2440 C  CE3    . TRP C 1 27 ? -1.74500  17.14400  9.33000   1.000 34.05257  ?  191 TRP C CE3    1 
ATOM   2441 C  CZ2    . TRP C 1 27 ? -3.10100  14.68000  9.04400   1.000 35.09759  ?  191 TRP C CZ2    1 
ATOM   2442 C  CZ3    . TRP C 1 27 ? -1.06100  15.96000  9.18600   1.000 33.36721  ?  191 TRP C CZ3    1 
ATOM   2443 C  CH2    . TRP C 1 27 ? -1.73000  14.74800  9.04500   1.000 34.59245  ?  191 TRP C CH2    1 
ATOM   2444 H  H      . TRP C 1 27 ? -4.87800  19.75700  11.91700  1.000 47.53285  ?  191 TRP C H      1 
ATOM   2445 H  HA     . TRP C 1 27 ? -2.41900  19.59500  10.96400  1.000 44.74295  ?  191 TRP C HA     1 
ATOM   2446 H  HB2    . TRP C 1 27 ? -4.87100  19.98300  9.63100   1.000 45.73744  ?  191 TRP C HB2    1 
ATOM   2447 H  HB3    . TRP C 1 27 ? -3.50600  19.89200  8.84000   1.000 45.73744  ?  191 TRP C HB3    1 
ATOM   2448 H  HD1    . TRP C 1 27 ? -6.18800  17.85600  9.43800   1.000 39.31024  ?  191 TRP C HD1    1 
ATOM   2449 H  HE1    . TRP C 1 27 ? -5.75600  15.51600  9.15600   1.000 48.76610  ?  191 TRP C HE1    1 
ATOM   2450 H  HE3    . TRP C 1 27 ? -1.28600  17.94700  9.42900   1.000 40.86309  ?  191 TRP C HE3    1 
ATOM   2451 H  HZ2    . TRP C 1 27 ? -3.54700  13.86900  8.94800   1.000 42.11711  ?  191 TRP C HZ2    1 
ATOM   2452 H  HZ3    . TRP C 1 27 ? -0.13100  15.96900  9.18300   1.000 40.04066  ?  191 TRP C HZ3    1 
ATOM   2453 H  HH2    . TRP C 1 27 ? -1.23700  13.96600  8.94800   1.000 41.51094  ?  191 TRP C HH2    1 
ATOM   2454 N  N      . VAL C 1 28 ? -1.61100  21.89600  10.42800  1.000 41.84796  ?  192 VAL C N      1 
ATOM   2455 C  CA     . VAL C 1 28 ? -1.12900  23.26300  10.10100  1.000 42.45291  ?  192 VAL C CA     1 
ATOM   2456 C  C      . VAL C 1 28 ? -1.10300  23.33300  8.57300   1.000 45.96440  ?  192 VAL C C      1 
ATOM   2457 O  O      . VAL C 1 28 ? -1.44900  24.38400  8.04500   1.000 51.75973  ?  192 VAL C O      1 
ATOM   2458 C  CB     . VAL C 1 28 ? 0.24800   23.50100  10.73900  1.000 44.80321  ?  192 VAL C CB     1 
ATOM   2459 C  CG1    . VAL C 1 28 ? 0.98500   24.66700  10.11300  1.000 45.94538  ?  192 VAL C CG1    1 
ATOM   2460 C  CG2    . VAL C 1 28 ? 0.14400   23.66900  12.24400  1.000 44.33584  ?  192 VAL C CG2    1 
ATOM   2461 H  H      . VAL C 1 28 ? -0.97500  21.31700  10.43600  1.000 50.21755  ?  192 VAL C H      1 
ATOM   2462 H  HA     . VAL C 1 28 ? -1.75300  23.92500  10.43800  1.000 50.94349  ?  192 VAL C HA     1 
ATOM   2463 H  HB     . VAL C 1 28 ? 0.78800   22.71100  10.58200  1.000 53.76386  ?  192 VAL C HB     1 
ATOM   2464 H  HG11   . VAL C 1 28 ? 1.74100   24.89900  10.67500  1.000 55.13445  ?  192 VAL C HG11   1 
ATOM   2465 H  HG12   . VAL C 1 28 ? 1.29700   24.41000  9.23100   1.000 55.13445  ?  192 VAL C HG12   1 
ATOM   2466 H  HG13   . VAL C 1 28 ? 0.38100   25.42300  10.04600  1.000 55.13445  ?  192 VAL C HG13   1 
ATOM   2467 H  HG21   . VAL C 1 28 ? 1.03300   23.80400  12.60900  1.000 53.20301  ?  192 VAL C HG21   1 
ATOM   2468 H  HG22   . VAL C 1 28 ? -0.41400  24.43800  12.43800  1.000 53.20301  ?  192 VAL C HG22   1 
ATOM   2469 H  HG23   . VAL C 1 28 ? -0.25100  22.86900  12.62400  1.000 53.20301  ?  192 VAL C HG23   1 
ATOM   2470 N  N      . ASP C 1 29 ? -0.72500  22.24600  7.90100   1.000 48.64294  ?  193 ASP C N      1 
ATOM   2471 C  CA     . ASP C 1 29 ? -0.72000  22.11500  6.42100   1.000 46.44595  ?  193 ASP C CA     1 
ATOM   2472 C  C      . ASP C 1 29 ? -0.99500  20.64500  6.13100   1.000 39.33250  ?  193 ASP C C      1 
ATOM   2473 O  O      . ASP C 1 29 ? -0.05900  19.90400  6.07700   1.000 46.09809  ?  193 ASP C O      1 
ATOM   2474 C  CB     . ASP C 1 29 ? 0.57200   22.63000  5.79600   1.000 56.84838  ?  193 ASP C CB     1 
ATOM   2475 C  CG     . ASP C 1 29 ? 0.59700   22.55600  4.28300   1.000 69.77622  ?  193 ASP C CG     1 
ATOM   2476 O  OD1    . ASP C 1 29 ? -0.38800  22.06600  3.69800   1.000 64.67859  ?  193 ASP C OD1    1 
ATOM   2477 O  OD2    . ASP C 1 29 ? 1.61100   22.98500  3.70800   1.000 84.45483  -1 193 ASP C OD2    1 
ATOM   2478 H  H      . ASP C 1 29 ? -0.45100  21.53100  8.29200   1.000 58.37152  ?  193 ASP C H      1 
ATOM   2479 H  HA     . ASP C 1 29 ? -1.45400  22.63400  6.05600   1.000 55.73514  ?  193 ASP C HA     1 
ATOM   2480 H  HB2    . ASP C 1 29 ? 0.69300   23.55900  6.04900   1.000 68.21805  ?  193 ASP C HB2    1 
ATOM   2481 H  HB3    . ASP C 1 29 ? 1.31300   22.10000  6.12900   1.000 68.21805  ?  193 ASP C HB3    1 
ATOM   2482 N  N      . LYS C 1 30 ? -2.23300  20.27200  5.88800   1.000 40.60189  ?  194 LYS C N      1 
ATOM   2483 C  CA     . LYS C 1 30 ? -2.66000  18.88400  5.75000   1.000 49.11517  ?  194 LYS C CA     1 
ATOM   2484 C  C      . LYS C 1 30 ? -1.95500  18.21600  4.58000   1.000 49.59921  ?  194 LYS C C      1 
ATOM   2485 O  O      . LYS C 1 30 ? -1.48600  17.07100  4.67900   1.000 42.30178  ?  194 LYS C O      1 
ATOM   2486 C  CB     . LYS C 1 30 ? -4.19100  18.82100  5.55500   1.000 44.13923  ?  194 LYS C CB     1 
ATOM   2487 C  CG     . LYS C 1 30 ? -4.77500  17.39000  5.58700   1.000 42.68723  ?  194 LYS C CG     1 
ATOM   2488 C  CD     . LYS C 1 30 ? -6.16900  17.24000  4.88400   1.000 48.20526  ?  194 LYS C CD     1 
ATOM   2489 C  CE     . LYS C 1 30 ? -7.32400  17.87000  5.61800   1.000 50.39177  ?  194 LYS C CE     1 
ATOM   2490 N  NZ     . LYS C 1 30 ? -8.61800  17.47500  4.98900   1.000 56.07676  ?  194 LYS C NZ     1 
ATOM   2491 H  H      . LYS C 1 30 ? -2.88100  20.83000  5.79300   1.000 48.72227  ?  194 LYS C H      1 
ATOM   2492 H  HA     . LYS C 1 30 ? -2.43600  18.39800  6.55900   1.000 58.93820  ?  194 LYS C HA     1 
ATOM   2493 H  HB2    . LYS C 1 30 ? -4.61600  19.32900  6.26300   1.000 52.96708  ?  194 LYS C HB2    1 
ATOM   2494 H  HB3    . LYS C 1 30 ? -4.41100  19.21100  4.69500   1.000 52.96708  ?  194 LYS C HB3    1 
ATOM   2495 H  HG2    . LYS C 1 30 ? -4.15800  16.78800  5.14300   1.000 51.22467  ?  194 LYS C HG2    1 
ATOM   2496 H  HG3    . LYS C 1 30 ? -4.88300  17.12100  6.51300   1.000 51.22467  ?  194 LYS C HG3    1 
ATOM   2497 H  HD2    . LYS C 1 30 ? -6.11900  17.65400  4.00800   1.000 57.84631  ?  194 LYS C HD2    1 
ATOM   2498 H  HD3    . LYS C 1 30 ? -6.36500  16.29500  4.78600   1.000 57.84631  ?  194 LYS C HD3    1 
ATOM   2499 H  HE2    . LYS C 1 30 ? -7.32500  17.56800  6.54000   1.000 60.47012  ?  194 LYS C HE2    1 
ATOM   2500 H  HE3    . LYS C 1 30 ? -7.24500  18.83600  5.57800   1.000 60.47012  ?  194 LYS C HE3    1 
ATOM   2501 H  HZ1    . LYS C 1 30 ? -9.29600  17.85000  5.42700   1.000 67.29211  ?  194 LYS C HZ1    1 
ATOM   2502 H  HZ2    . LYS C 1 30 ? -8.63800  17.74300  4.14100   1.000 67.29211  ?  194 LYS C HZ2    1 
ATOM   2503 H  HZ3    . LYS C 1 30 ? -8.71100  16.59000  5.01500   1.000 67.29211  ?  194 LYS C HZ3    1 
ATOM   2504 N  N      . ASP C 1 31 ? -1.85800  18.92100  3.45900   1.000 55.12206  ?  195 ASP C N      1 
ATOM   2505 C  CA     . ASP C 1 31 ? -1.26000  18.31100  2.26700   1.000 56.44570  ?  195 ASP C CA     1 
ATOM   2506 C  C      . ASP C 1 31 ? 0.18100   17.88900  2.50900   1.000 49.32652  ?  195 ASP C C      1 
ATOM   2507 O  O      . ASP C 1 31 ? 0.57200   16.77800  2.14400   1.000 49.63049  ?  195 ASP C O      1 
ATOM   2508 C  CB     . ASP C 1 31 ? -1.36400  19.28300  1.10400   1.000 60.00781  ?  195 ASP C CB     1 
ATOM   2509 C  CG     . ASP C 1 31 ? -2.76400  19.79600  0.94100   1.000 71.12371  ?  195 ASP C CG     1 
ATOM   2510 O  OD1    . ASP C 1 31 ? -3.69500  18.94300  1.01700   1.000 63.50419  ?  195 ASP C OD1    1 
ATOM   2511 O  OD2    . ASP C 1 31 ? -2.93000  21.04000  0.78800   1.000 83.74266  -1 195 ASP C OD2    1 
ATOM   2512 H  H      . ASP C 1 31 ? -2.11900  19.73400  3.36200   1.000 66.14647  ?  195 ASP C H      1 
ATOM   2513 H  HA     . ASP C 1 31 ? -1.76600  17.51600  2.03600   1.000 67.73484  ?  195 ASP C HA     1 
ATOM   2514 H  HB2    . ASP C 1 31 ? -0.77900  20.04000  1.26500   1.000 72.00937  ?  195 ASP C HB2    1 
ATOM   2515 H  HB3    . ASP C 1 31 ? -1.11000  18.83000  0.28500   1.000 72.00937  ?  195 ASP C HB3    1 
ATOM   2516 N  N      . LYS C 1 32 ? 0.98800   18.76200  3.12100   1.000 51.47842  ?  196 LYS C N      1 
ATOM   2517 C  CA     . LYS C 1 32 ? 2.36800   18.42700  3.49000   1.000 54.97442  ?  196 LYS C CA     1 
ATOM   2518 C  C      . LYS C 1 32 ? 2.50500   17.62100  4.79700   1.000 47.78098  ?  196 LYS C C      1 
ATOM   2519 O  O      . LYS C 1 32 ? 3.59700   17.15800  5.09400   1.000 50.21765  ?  196 LYS C O      1 
ATOM   2520 C  CB     . LYS C 1 32 ? 3.20800   19.70400  3.61900   1.000 63.53787  ?  196 LYS C CB     1 
ATOM   2521 C  CG     . LYS C 1 32 ? 3.68100   20.28500  2.30100   1.000 72.07583  ?  196 LYS C CG     1 
ATOM   2522 C  CD     . LYS C 1 32 ? 5.01000   21.04100  2.41600   1.000 77.86409  ?  196 LYS C CD     1 
ATOM   2523 C  CE     . LYS C 1 32 ? 5.58900   21.31900  1.01700   1.000 76.67874  ?  196 LYS C CE     1 
ATOM   2524 N  NZ     . LYS C 1 32 ? 4.75200   22.29500  0.23600   1.000 74.45749  ?  196 LYS C NZ     1 
ATOM   2525 H  H      . LYS C 1 32 ? 0.75700   19.56200  3.33500   1.000 61.77410  ?  196 LYS C H      1 
ATOM   2526 H  HA     . LYS C 1 32 ? 2.75400   17.89200  2.77900   1.000 65.96930  ?  196 LYS C HA     1 
ATOM   2527 H  HB2    . LYS C 1 32 ? 2.67500   20.38100  4.06400   1.000 76.24544  ?  196 LYS C HB2    1 
ATOM   2528 H  HB3    . LYS C 1 32 ? 3.99300   19.50500  4.15200   1.000 76.24544  ?  196 LYS C HB3    1 
ATOM   2529 H  HG2    . LYS C 1 32 ? 3.80300   19.56400  1.66400   1.000 86.49099  ?  196 LYS C HG2    1 
ATOM   2530 H  HG3    . LYS C 1 32 ? 3.01200   20.90600  1.97300   1.000 86.49099  ?  196 LYS C HG3    1 
ATOM   2531 H  HD2    . LYS C 1 32 ? 4.86200   21.89000  2.86200   1.000 93.43690  ?  196 LYS C HD2    1 
ATOM   2532 H  HD3    . LYS C 1 32 ? 5.64800   20.50300  2.91100   1.000 93.43690  ?  196 LYS C HD3    1 
ATOM   2533 H  HE2    . LYS C 1 32 ? 6.47900   21.69300  1.11100   1.000 92.01448  ?  196 LYS C HE2    1 
ATOM   2534 H  HE3    . LYS C 1 32 ? 5.62700   20.48800  0.51800   1.000 92.01448  ?  196 LYS C HE3    1 
ATOM   2535 H  HZ1    . LYS C 1 32 ? 5.10900   22.42600  -0.56900  1.000 89.34899  ?  196 LYS C HZ1    1 
ATOM   2536 H  HZ2    . LYS C 1 32 ? 3.92600   21.97700  0.13800   1.000 89.34899  ?  196 LYS C HZ2    1 
ATOM   2537 H  HZ3    . LYS C 1 32 ? 4.71300   23.07400  0.66500   1.000 89.34899  ?  196 LYS C HZ3    1 
ATOM   2538 N  N      . GLY C 1 33 ? 1.45500   17.42500  5.57900   1.000 48.12216  ?  197 GLY C N      1 
ATOM   2539 C  CA     . GLY C 1 33 ? 1.56100   16.55500  6.73700   1.000 41.53669  ?  197 GLY C CA     1 
ATOM   2540 C  C      . GLY C 1 33 ? 2.02500   17.22400  8.01500   1.000 38.37273  ?  197 GLY C C      1 
ATOM   2541 O  O      . GLY C 1 33 ? 2.47200   16.51900  8.92000   1.000 42.81817  ?  197 GLY C O      1 
ATOM   2542 H  H      . GLY C 1 33 ? 0.68000   17.77900  5.46400   1.000 57.74659  ?  197 GLY C H      1 
ATOM   2543 H  HA2    . GLY C 1 33 ? 0.69200   16.16000  6.90900   1.000 49.84403  ?  197 GLY C HA2    1 
ATOM   2544 H  HA3    . GLY C 1 33 ? 2.18000   15.83600  6.53600   1.000 49.84403  ?  197 GLY C HA3    1 
ATOM   2545 N  N      . THR C 1 34 ? 1.93700   18.55400  8.12100   1.000 39.78804  ?  198 THR C N      1 
ATOM   2546 C  CA     . THR C 1 34 ? 2.43700   19.27300  9.28200   1.000 40.79175  ?  198 THR C CA     1 
ATOM   2547 C  C      . THR C 1 34 ? 1.29000   19.51100  10.24900  1.000 40.94639  ?  198 THR C C      1 
ATOM   2548 O  O      . THR C 1 34 ? 0.22300   20.00900  9.84300   1.000 42.74567  ?  198 THR C O      1 
ATOM   2549 C  CB     . THR C 1 34 ? 3.06700   20.61500  8.90500   1.000 41.61458  ?  198 THR C CB     1 
ATOM   2550 O  OG1    . THR C 1 34 ? 2.06600   21.44500  8.35500   1.000 48.07082  ?  198 THR C OG1    1 
ATOM   2551 C  CG2    . THR C 1 34 ? 4.12000   20.44000  7.82800   1.000 45.84912  ?  198 THR C CG2    1 
ATOM   2552 H  H      . THR C 1 34 ? 1.58600   19.06300  7.52300   1.000 47.74565  ?  198 THR C H      1 
ATOM   2553 H  HA     . THR C 1 34 ? 3.10900   18.73600  9.72900   1.000 48.95010  ?  198 THR C HA     1 
ATOM   2554 H  HB     . THR C 1 34 ? 3.46600   21.03500  9.68300   1.000 49.93749  ?  198 THR C HB     1 
ATOM   2555 H  HG1    . THR C 1 34 ? 2.39400   22.18800  8.14200   1.000 57.68499  ?  198 THR C HG1    1 
ATOM   2556 H  HG21   . THR C 1 34 ? 4.55500   21.28800  7.65000   1.000 55.01894  ?  198 THR C HG21   1 
ATOM   2557 H  HG22   . THR C 1 34 ? 4.78700   19.79900  8.11800   1.000 55.01894  ?  198 THR C HG22   1 
ATOM   2558 H  HG23   . THR C 1 34 ? 3.70900   20.11900  7.01000   1.000 55.01894  ?  198 THR C HG23   1 
ATOM   2559 N  N      . PHE C 1 35 ? 1.53200   19.17200  11.51100  1.000 37.81340  ?  199 PHE C N      1 
ATOM   2560 C  CA     . PHE C 1 35 ? 0.54000   19.30100  12.56700  1.000 37.41328  ?  199 PHE C CA     1 
ATOM   2561 C  C      . PHE C 1 35 ? 1.15500   19.88000  13.83800  1.000 36.33223  ?  199 PHE C C      1 
ATOM   2562 O  O      . PHE C 1 35 ? 2.35500   19.76000  14.08700  1.000 37.07946  ?  199 PHE C O      1 
ATOM   2563 C  CB     . PHE C 1 35 ? -0.06100  17.94600  12.84300  1.000 37.56185  ?  199 PHE C CB     1 
ATOM   2564 C  CG     . PHE C 1 35 ? 0.92200   16.93500  13.37900  1.000 32.79347  ?  199 PHE C CG     1 
ATOM   2565 C  CD1    . PHE C 1 35 ? 1.07500   16.76700  14.75000  1.000 35.73670  ?  199 PHE C CD1    1 
ATOM   2566 C  CD2    . PHE C 1 35 ? 1.59300   16.11100  12.56300  1.000 31.96367  ?  199 PHE C CD2    1 
ATOM   2567 C  CE1    . PHE C 1 35 ? 1.92600   15.82200  15.28500  1.000 31.66125  ?  199 PHE C CE1    1 
ATOM   2568 C  CE2    . PHE C 1 35 ? 2.46200   15.14800  13.08900  1.000 34.79702  ?  199 PHE C CE2    1 
ATOM   2569 C  CZ     . PHE C 1 35 ? 2.60500   15.00900  14.47600  1.000 35.89533  ?  199 PHE C CZ     1 
ATOM   2570 H  H      . PHE C 1 35 ? 2.28400   18.85700  11.78500  1.000 45.37609  ?  199 PHE C H      1 
ATOM   2571 H  HA     . PHE C 1 35 ? -0.16800  19.89500  12.27300  1.000 44.89594  ?  199 PHE C HA     1 
ATOM   2572 H  HB2    . PHE C 1 35 ? -0.76900  18.04700  13.49900  1.000 45.07422  ?  199 PHE C HB2    1 
ATOM   2573 H  HB3    . PHE C 1 35 ? -0.42700  17.59300  12.01700  1.000 45.07422  ?  199 PHE C HB3    1 
ATOM   2574 H  HD1    . PHE C 1 35 ? 0.59900   17.32000  15.32600  1.000 42.88404  ?  199 PHE C HD1    1 
ATOM   2575 H  HD2    . PHE C 1 35 ? 1.49500   16.19100  11.64200  1.000 38.35641  ?  199 PHE C HD2    1 
ATOM   2576 H  HE1    . PHE C 1 35 ? 2.01700   15.74500  16.20700  1.000 37.99351  ?  199 PHE C HE1    1 
ATOM   2577 H  HE2    . PHE C 1 35 ? 2.93700   14.59000  12.51600  1.000 41.75642  ?  199 PHE C HE2    1 
ATOM   2578 H  HZ     . PHE C 1 35 ? 3.19100   14.37800  14.82700  1.000 43.07439  ?  199 PHE C HZ     1 
ATOM   2579 N  N      . GLN C 1 36 ? 0.29200   20.48500  14.66600  1.000 35.45357  ?  200 GLN C N      1 
ATOM   2580 C  CA     . GLN C 1 36 ? 0.70900   21.24200  15.83500  1.000 37.66374  ?  200 GLN C CA     1 
ATOM   2581 C  C      . GLN C 1 36 ? -0.12100  20.85400  17.05500  1.000 36.37091  ?  200 GLN C C      1 
ATOM   2582 O  O      . GLN C 1 36 ? -1.34100  20.65900  16.96000  1.000 34.27561  ?  200 GLN C O      1 
ATOM   2583 C  CB     . GLN C 1 36 ? 0.55900   22.70100  15.57000  1.000 35.81841  ?  200 GLN C CB     1 
ATOM   2584 C  CG     . GLN C 1 36 ? 0.96800   23.61300  16.67200  1.000 43.42707  ?  200 GLN C CG     1 
ATOM   2585 C  CD     . GLN C 1 36 ? 0.84000   25.03400  16.20800  1.000 46.17765  ?  200 GLN C CD     1 
ATOM   2586 O  OE1    . GLN C 1 36 ? -0.22600  25.44800  15.76600  1.000 47.08139  ?  200 GLN C OE1    1 
ATOM   2587 N  NE2    . GLN C 1 36 ? 1.95000   25.76600  16.22000  1.000 47.98783  ?  200 GLN C NE2    1 
ATOM   2588 H  H      . GLN C 1 36 ? -0.56100  20.46500  14.56100  1.000 42.54428  ?  200 GLN C H      1 
ATOM   2589 H  HA     . GLN C 1 36 ? 1.64100   21.05800  16.02600  1.000 45.19648  ?  200 GLN C HA     1 
ATOM   2590 H  HB2    . GLN C 1 36 ? 1.09700   22.92600  14.79500  1.000 42.98209  ?  200 GLN C HB2    1 
ATOM   2591 H  HB3    . GLN C 1 36 ? -0.37400  22.88100  15.37700  1.000 42.98209  ?  200 GLN C HB3    1 
ATOM   2592 H  HG2    . GLN C 1 36 ? 0.38700   23.48500  17.43800  1.000 52.11249  ?  200 GLN C HG2    1 
ATOM   2593 H  HG3    . GLN C 1 36 ? 1.89300   23.44500  16.91000  1.000 52.11249  ?  200 GLN C HG3    1 
ATOM   2594 H  HE21   . GLN C 1 36 ? 2.68200   25.43200  16.52400  1.000 57.58540  ?  200 GLN C HE21   1 
ATOM   2595 H  HE22   . GLN C 1 36 ? 1.92800   26.58400  15.95600  1.000 57.58540  ?  200 GLN C HE22   1 
ATOM   2596 N  N      . PHE C 1 37 ? 0.54000   20.81000  18.21200  1.000 32.61284  ?  201 PHE C N      1 
ATOM   2597 C  CA     . PHE C 1 37 ? -0.13900  20.62200  19.48500  1.000 36.84073  ?  201 PHE C CA     1 
ATOM   2598 C  C      . PHE C 1 37 ? -0.49500  21.97700  20.07100  1.000 38.78938  ?  201 PHE C C      1 
ATOM   2599 O  O      . PHE C 1 37 ? 0.22600   22.95300  19.89200  1.000 41.57437  ?  201 PHE C O      1 
ATOM   2600 C  CB     . PHE C 1 37 ? 0.72800   19.83400  20.49100  1.000 35.65110  ?  201 PHE C CB     1 
ATOM   2601 C  CG     . PHE C 1 37 ? 0.99500   18.41700  20.08700  1.000 34.54664  ?  201 PHE C CG     1 
ATOM   2602 C  CD1    . PHE C 1 37 ? 0.03600   17.42600  20.31900  1.000 31.28442  ?  201 PHE C CD1    1 
ATOM   2603 C  CD2    . PHE C 1 37 ? 2.20300   18.05700  19.48700  1.000 29.55850  ?  201 PHE C CD2    1 
ATOM   2604 C  CE1    . PHE C 1 37 ? 0.24900   16.09400  19.93700  1.000 30.68591  ?  201 PHE C CE1    1 
ATOM   2605 C  CE2    . PHE C 1 37 ? 2.42200   16.72300  19.11100  1.000 30.87096  ?  201 PHE C CE2    1 
ATOM   2606 C  CZ     . PHE C 1 37 ? 1.41000   15.73300  19.34900  1.000 29.19657  ?  201 PHE C CZ     1 
ATOM   2607 H  H      . PHE C 1 37 ? 1.39400   20.88800  18.28300  1.000 39.13541  ?  201 PHE C H      1 
ATOM   2608 H  HA     . PHE C 1 37 ? -0.96100  20.12700  19.34100  1.000 44.20887  ?  201 PHE C HA     1 
ATOM   2609 H  HB2    . PHE C 1 37 ? 1.58400   20.28200  20.58300  1.000 42.78132  ?  201 PHE C HB2    1 
ATOM   2610 H  HB3    . PHE C 1 37 ? 0.27300   19.81700  21.34800  1.000 42.78132  ?  201 PHE C HB3    1 
ATOM   2611 H  HD1    . PHE C 1 37 ? -0.77200  17.66100  20.71400  1.000 37.54130  ?  201 PHE C HD1    1 
ATOM   2612 H  HD2    . PHE C 1 37 ? 2.85400   18.70100  19.32500  1.000 35.47020  ?  201 PHE C HD2    1 
ATOM   2613 H  HE1    . PHE C 1 37 ? -0.40700  15.45500  20.09900  1.000 36.82310  ?  201 PHE C HE1    1 
ATOM   2614 H  HE2    . PHE C 1 37 ? 3.22300   16.48000  18.70700  1.000 37.04515  ?  201 PHE C HE2    1 
ATOM   2615 H  HZ     . PHE C 1 37 ? 1.55600   14.84700  19.10600  1.000 35.03588  ?  201 PHE C HZ     1 
ATOM   2616 N  N      . SER C 1 38 ? -1.61900  22.00800  20.77000  1.000 40.44289  ?  202 SER C N      1 
ATOM   2617 C  CA     . SER C 1 38 ? -2.03000  23.13800  21.59900  1.000 44.22270  ?  202 SER C CA     1 
ATOM   2618 C  C      . SER C 1 38 ? -1.15600  23.26500  22.83500  1.000 44.88241  ?  202 SER C C      1 
ATOM   2619 O  O      . SER C 1 38 ? -0.95500  22.28300  23.55400  1.000 45.15324  ?  202 SER C O      1 
ATOM   2620 C  CB     . SER C 1 38 ? -3.47600  22.91900  22.04800  1.000 42.43099  ?  202 SER C CB     1 
ATOM   2621 O  OG     . SER C 1 38 ? -3.80300  23.65700  23.21200  1.000 47.94905  ?  202 SER C OG     1 
ATOM   2622 H  H      . SER C 1 38 ? -2.18400  21.36000  20.78100  1.000 48.53146  ?  202 SER C H      1 
ATOM   2623 H  HA     . SER C 1 38 ? -1.97800  23.96100  21.08900  1.000 53.06724  ?  202 SER C HA     1 
ATOM   2624 H  HB2    . SER C 1 38 ? -4.06900  23.19500  21.33500  1.000 50.91719  ?  202 SER C HB2    1 
ATOM   2625 H  HB3    . SER C 1 38 ? -3.60500  21.97600  22.23300  1.000 50.91719  ?  202 SER C HB3    1 
ATOM   2626 H  HG     . SER C 1 38 ? -4.63100  23.63000  23.34700  1.000 57.53886  ?  202 SER C HG     1 
ATOM   2627 N  N      . SER C 1 39 ? -0.69700  24.48100  23.13900  1.000 45.32649  ?  203 SER C N      1 
ATOM   2628 C  CA     . SER C 1 39 ? 0.05400   24.66500  24.38500  1.000 51.20595  ?  203 SER C CA     1 
ATOM   2629 C  C      . SER C 1 39 ? -0.78000  24.27900  25.60700  1.000 48.89978  ?  203 SER C C      1 
ATOM   2630 O  O      . SER C 1 39 ? -0.32500  23.50900  26.45900  1.000 50.82318  ?  203 SER C O      1 
ATOM   2631 C  CB     . SER C 1 39 ? 0.55100   26.09400  24.53200  1.000 51.82622  ?  203 SER C CB     1 
ATOM   2632 O  OG     . SER C 1 39 ? 1.29100   26.18100  25.73800  1.000 55.40470  ?  203 SER C OG     1 
ATOM   2633 H  H      . SER C 1 39 ? -0.80100  25.19000  22.66300  1.000 54.39179  ?  203 SER C H      1 
ATOM   2634 H  HA     . SER C 1 39 ? 0.83100   24.08500  24.36500  1.000 61.44715  ?  203 SER C HA     1 
ATOM   2635 H  HB2    . SER C 1 39 ? 1.12500   26.31700  23.78200  1.000 62.19146  ?  203 SER C HB2    1 
ATOM   2636 H  HB3    . SER C 1 39 ? -0.20700  26.69800  24.57200  1.000 62.19146  ?  203 SER C HB3    1 
ATOM   2637 H  HG     . SER C 1 39 ? 1.94300   25.65200  25.71400  1.000 66.48563  ?  203 SER C HG     1 
ATOM   2638 N  N      . LYS C 1 40 ? -2.02500  24.75500  25.66700  0.889 48.92465  ?  204 LYS C N      1 
ATOM   2639 C  CA     . LYS C 1 40 ? -2.88700  24.57000  26.83000  1.000 48.72000  ?  204 LYS C CA     1 
ATOM   2640 C  C      . LYS C 1 40 ? -3.52000  23.19100  26.90600  1.000 49.70023  ?  204 LYS C C      1 
ATOM   2641 O  O      . LYS C 1 40 ? -3.79100  22.71300  28.00200  1.000 55.09865  ?  204 LYS C O      1 
ATOM   2642 C  CB     . LYS C 1 40 ? -4.00500  25.63000  26.83400  1.000 55.64973  ?  204 LYS C CB     1 
ATOM   2643 C  CG     . LYS C 1 40 ? -3.47700  27.07300  26.93600  1.000 59.15599  ?  204 LYS C CG     1 
ATOM   2644 C  CD     . LYS C 1 40 ? -4.30200  27.97000  27.86300  0.785 62.16500  ?  204 LYS C CD     1 
ATOM   2645 C  CE     . LYS C 1 40 ? -3.72800  29.37900  27.90400  0.000 63.22569  ?  204 LYS C CE     1 
ATOM   2646 N  NZ     . LYS C 1 40 ? -3.39800  29.81800  29.28500  1.000 70.41609  ?  204 LYS C NZ     1 
ATOM   2647 H  H      . LYS C 1 40 ? -2.39800  25.19800  25.03100  0.900 58.70957  ?  204 LYS C H      1 
ATOM   2648 H  HA     . LYS C 1 40 ? -2.35700  24.69600  27.63300  1.000 58.46400  ?  204 LYS C HA     1 
ATOM   2649 H  HB2    . LYS C 1 40 ? -4.51100  25.55500  26.01000  1.000 66.77967  ?  204 LYS C HB2    1 
ATOM   2650 H  HB3    . LYS C 1 40 ? -4.58600  25.47100  27.59400  1.000 66.77967  ?  204 LYS C HB3    1 
ATOM   2651 H  HG2    . LYS C 1 40 ? -2.56900  27.05000  27.27700  1.000 70.98718  ?  204 LYS C HG2    1 
ATOM   2652 H  HG3    . LYS C 1 40 ? -3.48600  27.47200  26.05200  1.000 70.98718  ?  204 LYS C HG3    1 
ATOM   2653 H  HD2    . LYS C 1 40 ? -5.21400  28.02000  27.53500  0.752 74.59800  ?  204 LYS C HD2    1 
ATOM   2654 H  HD3    . LYS C 1 40 ? -4.28500  27.60600  28.76200  0.725 74.59800  ?  204 LYS C HD3    1 
ATOM   2655 H  HE2    . LYS C 1 40 ? -2.91400  29.40500  27.37700  0.000 75.87083  ?  204 LYS C HE2    1 
ATOM   2656 H  HE3    . LYS C 1 40 ? -4.38000  29.99800  27.53900  0.000 75.87083  ?  204 LYS C HE3    1 
ATOM   2657 H  HZ1    . LYS C 1 40 ? -3.06600  30.64400  29.27000  1.000 84.49931  ?  204 LYS C HZ1    1 
ATOM   2658 H  HZ2    . LYS C 1 40 ? -4.13100  29.81000  29.79000  1.000 84.49931  ?  204 LYS C HZ2    1 
ATOM   2659 H  HZ3    . LYS C 1 40 ? -2.79500  29.27000  29.64200  1.000 84.49931  ?  204 LYS C HZ3    1 
ATOM   2660 N  N      . HIS C 1 41 ? -3.77700  22.52900  25.77900  1.000 46.30075  ?  205 HIS C N      1 
ATOM   2661 C  CA     . HIS C 1 41 ? -4.58900  21.32600  25.79100  1.000 46.86931  ?  205 HIS C CA     1 
ATOM   2662 C  C      . HIS C 1 41 ? -3.82000  20.05900  25.45600  1.000 43.20106  ?  205 HIS C C      1 
ATOM   2663 O  O      . HIS C 1 41 ? -4.43800  18.98200  25.32200  1.000 41.74159  ?  205 HIS C O      1 
ATOM   2664 C  CB     . HIS C 1 41 ? -5.77200  21.50600  24.84000  1.000 54.35761  ?  205 HIS C CB     1 
ATOM   2665 C  CG     . HIS C 1 41 ? -6.79100  22.48300  25.34400  1.000 62.20860  ?  205 HIS C CG     1 
ATOM   2666 N  ND1    . HIS C 1 41 ? -7.85800  22.10200  26.13600  1.000 73.81352  ?  205 HIS C ND1    1 
ATOM   2667 C  CD2    . HIS C 1 41 ? -6.88400  23.83200  25.21600  1.000 63.69866  ?  205 HIS C CD2    1 
ATOM   2668 C  CE1    . HIS C 1 41 ? -8.59000  23.17200  26.43800  1.000 78.77249  ?  205 HIS C CE1    1 
ATOM   2669 N  NE2    . HIS C 1 41 ? -8.00100  24.23100  25.91100  1.000 73.84278  ?  205 HIS C NE2    1 
ATOM   2670 H  H      . HIS C 1 41 ? -3.49200  22.75800  25.00000  1.000 55.56090  ?  205 HIS C H      1 
ATOM   2671 H  HA     . HIS C 1 41 ? -4.95700  21.20800  26.68000  1.000 56.24318  ?  205 HIS C HA     1 
ATOM   2672 H  HB2    . HIS C 1 41 ? -5.44300  21.82800  23.98700  1.000 65.22914  ?  205 HIS C HB2    1 
ATOM   2673 H  HB3    . HIS C 1 41 ? -6.21300  20.65000  24.72200  1.000 65.22914  ?  205 HIS C HB3    1 
ATOM   2674 H  HD2    . HIS C 1 41 ? -6.30000  24.38300  24.74700  1.000 76.43839  ?  205 HIS C HD2    1 
ATOM   2675 H  HE1    . HIS C 1 41 ? -9.36000  23.17800  26.95900  1.000 94.52698  ?  205 HIS C HE1    1 
ATOM   2676 H  HE2    . HIS C 1 41 ? -8.28700  25.04000  25.96900  1.000 88.61133  ?  205 HIS C HE2    1 
ATOM   2677 N  N      . LYS C 1 42 ? -2.49200  20.14700  25.31600  1.000 43.88547  ?  206 LYS C N      1 
ATOM   2678 C  CA     . LYS C 1 42 ? -1.72200  18.98200  24.89700  1.000 37.40185  ?  206 LYS C CA     1 
ATOM   2679 C  C      . LYS C 1 42 ? -1.69900  17.87800  25.95000  1.000 37.71250  ?  206 LYS C C      1 
ATOM   2680 O  O      . LYS C 1 42 ? -1.52100  16.71400  25.58600  1.000 34.83748  ?  206 LYS C O      1 
ATOM   2681 C  CB     . LYS C 1 42 ? -0.28100  19.37900  24.55800  1.000 35.04422  ?  206 LYS C CB     1 
ATOM   2682 C  CG     . LYS C 1 42 ? 0.46900   20.16000  25.55600  1.000 37.83395  ?  206 LYS C CG     1 
ATOM   2683 C  CD     . LYS C 1 42 ? 1.78800   20.63400  24.97800  1.000 39.58653  ?  206 LYS C CD     1 
ATOM   2684 C  CE     . LYS C 1 42 ? 2.75500   21.10400  26.04700  1.000 41.50262  ?  206 LYS C CE     1 
ATOM   2685 N  NZ     . LYS C 1 42 ? 2.15300   22.19000  26.78000  1.000 46.92685  ?  206 LYS C NZ     1 
ATOM   2686 H  H      . LYS C 1 42 ? -2.02900  20.85700  25.45300  1.000 52.66256  ?  206 LYS C H      1 
ATOM   2687 H  HA     . LYS C 1 42 ? -2.12500  18.61600  24.09400  1.000 44.88222  ?  206 LYS C HA     1 
ATOM   2688 H  HB2    . LYS C 1 42 ? 0.22300   18.56500  24.40000  1.000 42.05306  ?  206 LYS C HB2    1 
ATOM   2689 H  HB3    . LYS C 1 42 ? -0.29900  19.90400  23.74300  1.000 42.05306  ?  206 LYS C HB3    1 
ATOM   2690 H  HG2    . LYS C 1 42 ? -0.04500  20.93900  25.81700  1.000 45.40074  ?  206 LYS C HG2    1 
ATOM   2691 H  HG3    . LYS C 1 42 ? 0.65500   19.60300  26.32800  1.000 45.40074  ?  206 LYS C HG3    1 
ATOM   2692 H  HD2    . LYS C 1 42 ? 2.20400   19.91000  24.49000  1.000 47.50383  ?  206 LYS C HD2    1 
ATOM   2693 H  HD3    . LYS C 1 42 ? 1.61900   21.38000  24.38100  1.000 47.50383  ?  206 LYS C HD3    1 
ATOM   2694 H  HE2    . LYS C 1 42 ? 2.94200   20.37800  26.66300  1.000 49.80315  ?  206 LYS C HE2    1 
ATOM   2695 H  HE3    . LYS C 1 42 ? 3.57200   21.42300  25.63300  1.000 49.80315  ?  206 LYS C HE3    1 
ATOM   2696 H  HZ1    . LYS C 1 42 ? 2.73300   22.51700  27.37000  1.000 56.31222  ?  206 LYS C HZ1    1 
ATOM   2697 H  HZ2    . LYS C 1 42 ? 1.91400   22.83900  26.22000  1.000 56.31222  ?  206 LYS C HZ2    1 
ATOM   2698 H  HZ3    . LYS C 1 42 ? 1.43100   21.90200  27.21300  1.000 56.31222  ?  206 LYS C HZ3    1 
ATOM   2699 N  N      . GLU C 1 43 ? -1.84600  18.21500  27.25700  1.000 37.29669  ?  207 GLU C N      1 
ATOM   2700 C  CA     . GLU C 1 43 ? -1.70000  17.19100  28.29600  1.000 38.86508  ?  207 GLU C CA     1 
ATOM   2701 C  C      . GLU C 1 43 ? -2.89400  16.24200  28.32000  1.000 37.64513  ?  207 GLU C C      1 
ATOM   2702 O  O      . GLU C 1 43 ? -2.73600  15.07500  28.67400  1.000 37.25303  ?  207 GLU C O      1 
ATOM   2703 C  CB     . GLU C 1 43 ? -1.49800  17.84600  29.66500  1.000 34.02763  ?  207 GLU C CB     1 
ATOM   2704 C  CG     . GLU C 1 43 ? -0.29300  18.73500  29.69300  1.000 42.80126  ?  207 GLU C CG     1 
ATOM   2705 C  CD     . GLU C 1 43 ? 1.06100   18.00700  29.58000  1.000 44.48833  ?  207 GLU C CD     1 
ATOM   2706 O  OE1    . GLU C 1 43 ? 1.13100   16.75400  29.61700  1.000 40.92636  ?  207 GLU C OE1    1 
ATOM   2707 O  OE2    . GLU C 1 43 ? 2.07900   18.73200  29.47200  1.000 45.45033  -1 207 GLU C OE2    1 
ATOM   2708 H  H      . GLU C 1 43 ? -2.02400  19.00400  27.54900  1.000 44.75603  ?  207 GLU C H      1 
ATOM   2709 H  HA     . GLU C 1 43 ? -0.91000  16.66300  28.10200  1.000 46.63810  ?  207 GLU C HA     1 
ATOM   2710 H  HB2    . GLU C 1 43 ? -2.27600  18.38500  29.87800  1.000 40.83316  ?  207 GLU C HB2    1 
ATOM   2711 H  HB3    . GLU C 1 43 ? -1.37800  17.15400  30.33400  1.000 40.83316  ?  207 GLU C HB3    1 
ATOM   2712 H  HG2    . GLU C 1 43 ? -0.34600  19.35800  28.95300  1.000 51.36152  ?  207 GLU C HG2    1 
ATOM   2713 H  HG3    . GLU C 1 43 ? -0.29200  19.22500  30.53000  1.000 51.36152  ?  207 GLU C HG3    1 
ATOM   2714 N  N      . ALA C 1 44 ? -4.07400  16.68500  27.88600  1.000 40.73508  ?  208 ALA C N      1 
ATOM   2715 C  CA     . ALA C 1 44 ? -5.20300  15.76400  27.76100  1.000 35.09656  ?  208 ALA C CA     1 
ATOM   2716 C  C      . ALA C 1 44 ? -4.94100  14.71600  26.67100  1.000 33.76957  ?  208 ALA C C      1 
ATOM   2717 O  O      . ALA C 1 44 ? -5.21600  13.50400  26.85400  1.000 36.02661  ?  208 ALA C O      1 
ATOM   2718 C  CB     . ALA C 1 44 ? -6.45700  16.57500  27.48900  1.000 41.45300  ?  208 ALA C CB     1 
ATOM   2719 H  H      . ALA C 1 44 ? -4.24500  17.49700  27.66200  1.000 48.88210  ?  208 ALA C H      1 
ATOM   2720 H  HA     . ALA C 1 44 ? -5.32500  15.29700  28.60200  1.000 42.11588  ?  208 ALA C HA     1 
ATOM   2721 H  HB1    . ALA C 1 44 ? -7.21100  15.97100  27.40500  1.000 49.74360  ?  208 ALA C HB1    1 
ATOM   2722 H  HB2    . ALA C 1 44 ? -6.60300  17.18700  28.22800  1.000 49.74360  ?  208 ALA C HB2    1 
ATOM   2723 H  HB3    . ALA C 1 44 ? -6.33800  17.07300  26.66500  1.000 49.74360  ?  208 ALA C HB3    1 
ATOM   2724 N  N      . LEU C 1 45 ? -4.36800  15.13900  25.55100  1.000 37.44766  ?  209 LEU C N      1 
ATOM   2725 C  CA     . LEU C 1 45 ? -4.03200  14.16800  24.50400  1.000 34.80304  ?  209 LEU C CA     1 
ATOM   2726 C  C      . LEU C 1 45 ? -2.93100  13.20700  24.98000  1.000 29.51272  ?  209 LEU C C      1 
ATOM   2727 O  O      . LEU C 1 45 ? -3.02000  11.99400  24.77100  1.000 26.54183  ?  209 LEU C O      1 
ATOM   2728 C  CB     . LEU C 1 45 ? -3.58600  14.90800  23.24100  1.000 31.38314  ?  209 LEU C CB     1 
ATOM   2729 C  CG     . LEU C 1 45 ? -3.55400  14.04200  21.99300  1.000 38.37502  ?  209 LEU C CG     1 
ATOM   2730 C  CD1    . LEU C 1 45 ? -3.63000  14.96700  20.73300  1.000 30.37921  ?  209 LEU C CD1    1 
ATOM   2731 C  CD2    . LEU C 1 45 ? -2.37400  13.18700  22.02400  1.000 36.14621  ?  209 LEU C CD2    1 
ATOM   2732 H  H      . LEU C 1 45 ? -4.16700  15.95500  25.37100  1.000 44.93719  ?  209 LEU C H      1 
ATOM   2733 H  HA     . LEU C 1 45 ? -4.81700  13.64200  24.28800  1.000 41.76365  ?  209 LEU C HA     1 
ATOM   2734 H  HB2    . LEU C 1 45 ? -4.20900  15.63200  23.07500  1.000 37.65977  ?  209 LEU C HB2    1 
ATOM   2735 H  HB3    . LEU C 1 45 ? -2.69900  15.27200  23.38600  1.000 37.65977  ?  209 LEU C HB3    1 
ATOM   2736 H  HG     . LEU C 1 45 ? -4.33700  13.46900  21.98900  1.000 46.05002  ?  209 LEU C HG     1 
ATOM   2737 H  HD11   . LEU C 1 45 ? -3.54100  14.42200  19.93500  1.000 36.45505  ?  209 LEU C HD11   1 
ATOM   2738 H  HD12   . LEU C 1 45 ? -4.48600  15.42400  20.72800  1.000 36.45505  ?  209 LEU C HD12   1 
ATOM   2739 H  HD13   . LEU C 1 45 ? -2.90900  15.61400  20.77400  1.000 36.45505  ?  209 LEU C HD13   1 
ATOM   2740 H  HD21   . LEU C 1 45 ? -2.07900  13.03000  21.11300  1.000 43.37545  ?  209 LEU C HD21   1 
ATOM   2741 H  HD22   . LEU C 1 45 ? -1.66800  13.62200  22.52600  1.000 43.37545  ?  209 LEU C HD22   1 
ATOM   2742 H  HD23   . LEU C 1 45 ? -2.60600  12.34400  22.44200  1.000 43.37545  ?  209 LEU C HD23   1 
ATOM   2743 N  N      . ALA C 1 46 ? -1.89500  13.73600  25.64100  1.000 32.25647  ?  210 ALA C N      1 
ATOM   2744 C  CA     . ALA C 1 46 ? -0.86700  12.86100  26.22000  1.000 28.22708  ?  210 ALA C CA     1 
ATOM   2745 C  C      . ALA C 1 46 ? -1.48700  11.85600  27.19000  1.000 31.27680  ?  210 ALA C C      1 
ATOM   2746 O  O      . ALA C 1 46 ? -1.17500  10.65800  27.15500  1.000 29.13625  ?  210 ALA C O      1 
ATOM   2747 C  CB     . ALA C 1 46 ? 0.18300   13.69300  26.94400  1.000 31.58428  ?  210 ALA C CB     1 
ATOM   2748 H  H      . ALA C 1 46 ? -1.76500  14.57700  25.76600  1.000 38.70776  ?  210 ALA C H      1 
ATOM   2749 H  HA     . ALA C 1 46 ? -0.42800  12.36800  25.50900  1.000 33.87250  ?  210 ALA C HA     1 
ATOM   2750 H  HB1    . ALA C 1 46 ? 0.85700   13.10200  27.31200  1.000 37.90113  ?  210 ALA C HB1    1 
ATOM   2751 H  HB2    . ALA C 1 46 ? 0.59000   14.30500  26.31200  1.000 37.90113  ?  210 ALA C HB2    1 
ATOM   2752 H  HB3    . ALA C 1 46 ? -0.24600  14.19100  27.65700  1.000 37.90113  ?  210 ALA C HB3    1 
ATOM   2753 N  N      . HIS C 1 47 ? -2.32900  12.35700  28.08900  1.000 31.79505  ?  211 HIS C N      1 
ATOM   2754 C  CA     . HIS C 1 47 ? -3.03400  11.50800  29.05000  1.000 36.11085  ?  211 HIS C CA     1 
ATOM   2755 C  C      . HIS C 1 47 ? -3.68100  10.33700  28.31700  1.000 38.49986  ?  211 HIS C C      1 
ATOM   2756 O  O      . HIS C 1 47 ? -3.52900  9.16600   28.70700  1.000 37.47439  ?  211 HIS C O      1 
ATOM   2757 C  CB     . HIS C 1 47 ? -4.09800  12.38800  29.78500  1.000 32.04424  ?  211 HIS C CB     1 
ATOM   2758 C  CG     . HIS C 1 47 ? -4.75500  11.74000  30.96100  1.000 44.23117  ?  211 HIS C CG     1 
ATOM   2759 N  ND1    . HIS C 1 47 ? -6.06000  12.08200  31.39600  1.000 44.18262  ?  211 HIS C ND1    1 
ATOM   2760 C  CD2    . HIS C 1 47 ? -4.30600  10.76400  31.77300  1.000 39.31814  ?  211 HIS C CD2    1 
ATOM   2761 C  CE1    . HIS C 1 47 ? -6.31900  11.30300  32.44000  1.000 52.07228  ?  211 HIS C CE1    1 
ATOM   2762 N  NE2    . HIS C 1 47 ? -5.29300  10.51100  32.68500  1.000 44.99498  ?  211 HIS C NE2    1 
ATOM   2763 H  H      . HIS C 1 47 ? -2.51200  13.19400  28.16500  1.000 38.15406  ?  211 HIS C H      1 
ATOM   2764 H  HA     . HIS C 1 47 ? -2.40700  11.16100  29.70400  1.000 43.33302  ?  211 HIS C HA     1 
ATOM   2765 H  HB2    . HIS C 1 47 ? -3.66400  13.19600  30.10100  1.000 38.45309  ?  211 HIS C HB2    1 
ATOM   2766 H  HB3    . HIS C 1 47 ? -4.79600  12.62000  29.15300  1.000 38.45309  ?  211 HIS C HB3    1 
ATOM   2767 H  HD2    . HIS C 1 47 ? -3.48200  10.33700  31.71900  1.000 47.18177  ?  211 HIS C HD2    1 
ATOM   2768 H  HE1    . HIS C 1 47 ? -7.02100  11.25200  33.00000  1.000 62.48673  ?  211 HIS C HE1    1 
ATOM   2769 H  HE2    . HIS C 1 47 ? -5.24900  9.93400   33.32100  1.000 53.99398  ?  211 HIS C HE2    1 
ATOM   2770 N  N      . ARG C 1 48 ? -4.37300  10.65100  27.20200  1.000 33.37424  ?  212 ARG C N      1 
ATOM   2771 C  CA     . ARG C 1 48 ? -5.14100  9.63100   26.49500  1.000 37.29567  ?  212 ARG C CA     1 
ATOM   2772 C  C      . ARG C 1 48 ? -4.22000  8.62000   25.82100  1.000 35.76026  ?  212 ARG C C      1 
ATOM   2773 O  O      . ARG C 1 48 ? -4.53400  7.42900   25.74100  1.000 36.88275  ?  212 ARG C O      1 
ATOM   2774 C  CB     . ARG C 1 48 ? -6.06800  10.32500  25.47500  1.000 36.04842  ?  212 ARG C CB     1 
ATOM   2775 C  CG     . ARG C 1 48 ? -6.79200  9.40400   24.55500  1.000 38.81621  ?  212 ARG C CG     1 
ATOM   2776 C  CD     . ARG C 1 48 ? -7.61300  10.19400  23.52100  1.000 40.56193  ?  212 ARG C CD     1 
ATOM   2777 N  NE     . ARG C 1 48 ? -8.10800  9.27500   22.50900  1.000 40.88735  ?  212 ARG C NE     1 
ATOM   2778 C  CZ     . ARG C 1 48 ? -9.07200  9.52300   21.62400  1.000 43.18542  ?  212 ARG C CZ     1 
ATOM   2779 N  NH1    . ARG C 1 48 ? -9.71100  10.68900  21.57300  1.000 38.56557  ?  212 ARG C NH1    1 
ATOM   2780 N  NH2    . ARG C 1 48 ? -9.40900  8.57100   20.77600  1.000 48.30274  ?  212 ARG C NH2    1 
ATOM   2781 H  H      . ARG C 1 48 ? -4.40800  11.43400  26.84900  1.000 40.04909  ?  212 ARG C H      1 
ATOM   2782 H  HA     . ARG C 1 48 ? -5.69700  9.15400   27.13100  1.000 44.75481  ?  212 ARG C HA     1 
ATOM   2783 H  HB2    . ARG C 1 48 ? -6.73400  10.83600  25.96100  1.000 43.25810  ?  212 ARG C HB2    1 
ATOM   2784 H  HB3    . ARG C 1 48 ? -5.53400  10.92300  24.92900  1.000 43.25810  ?  212 ARG C HB3    1 
ATOM   2785 H  HG2    . ARG C 1 48 ? -6.15600  8.85400   24.07300  1.000 46.57946  ?  212 ARG C HG2    1 
ATOM   2786 H  HG3    . ARG C 1 48 ? -7.39900  8.84800   25.06800  1.000 46.57946  ?  212 ARG C HG3    1 
ATOM   2787 H  HD2    . ARG C 1 48 ? -8.37000  10.61700  23.95600  1.000 48.67432  ?  212 ARG C HD2    1 
ATOM   2788 H  HD3    . ARG C 1 48 ? -7.04900  10.85600  23.09200  1.000 48.67432  ?  212 ARG C HD3    1 
ATOM   2789 H  HE     . ARG C 1 48 ? -7.74300  8.49700   22.47900  1.000 49.06483  ?  212 ARG C HE     1 
ATOM   2790 H  HH11   . ARG C 1 48 ? -9.50300  11.31800  22.12100  1.000 46.27868  ?  212 ARG C HH11   1 
ATOM   2791 H  HH12   . ARG C 1 48 ? -10.33000 10.81500  20.98900  1.000 46.27868  ?  212 ARG C HH12   1 
ATOM   2792 H  HH21   . ARG C 1 48 ? -9.00500  7.81200   20.79900  1.000 57.96328  ?  212 ARG C HH21   1 
ATOM   2793 H  HH22   . ARG C 1 48 ? -10.03000 8.71100   20.19700  1.000 57.96328  ?  212 ARG C HH22   1 
ATOM   2794 N  N      . TRP C 1 49 ? -3.06300  9.05900   25.35500  1.000 35.11449  ?  213 TRP C N      1 
ATOM   2795 C  CA     . TRP C 1 49 ? -2.10300  8.08700   24.81500  1.000 34.75376  ?  213 TRP C CA     1 
ATOM   2796 C  C      . TRP C 1 49 ? -1.67300  7.08900   25.90600  1.000 34.10430  ?  213 TRP C C      1 
ATOM   2797 O  O      . TRP C 1 49 ? -1.62200  5.87100   25.68200  1.000 33.93866  ?  213 TRP C O      1 
ATOM   2798 C  CB     . TRP C 1 49 ? -0.91700  8.85000   24.22000  1.000 33.14967  ?  213 TRP C CB     1 
ATOM   2799 C  CG     . TRP C 1 49 ? 0.26800   7.99900   23.87600  1.000 32.97144  ?  213 TRP C CG     1 
ATOM   2800 C  CD1    . TRP C 1 49 ? 1.56500   8.15600   24.31700  1.000 33.44905  ?  213 TRP C CD1    1 
ATOM   2801 C  CD2    . TRP C 1 49 ? 0.29000   6.88900   22.97300  1.000 34.20942  ?  213 TRP C CD2    1 
ATOM   2802 N  NE1    . TRP C 1 49 ? 2.35300   7.18600   23.78200  1.000 33.47846  ?  213 TRP C NE1    1 
ATOM   2803 C  CE2    . TRP C 1 49 ? 1.59800   6.38300   22.96600  1.000 34.74104  ?  213 TRP C CE2    1 
ATOM   2804 C  CE3    . TRP C 1 49 ? -0.67500  6.27400   22.17900  1.000 33.12162  ?  213 TRP C CE3    1 
ATOM   2805 C  CZ2    . TRP C 1 49 ? 1.96600   5.28900   22.20300  1.000 34.11909  ?  213 TRP C CZ2    1 
ATOM   2806 C  CZ3    . TRP C 1 49 ? -0.32000  5.17500   21.45000  1.000 33.13109  ?  213 TRP C CZ3    1 
ATOM   2807 C  CH2    . TRP C 1 49 ? 0.98700   4.69800   21.45600  1.000 35.41916  ?  213 TRP C CH2    1 
ATOM   2808 H  H      . TRP C 1 49 ? -2.80800  9.88000   25.33500  1.000 42.13739  ?  213 TRP C H      1 
ATOM   2809 H  HA     . TRP C 1 49 ? -2.52700  7.58600   24.10100  1.000 41.70451  ?  213 TRP C HA     1 
ATOM   2810 H  HB2    . TRP C 1 49 ? -1.20800  9.29000   23.40700  1.000 39.77960  ?  213 TRP C HB2    1 
ATOM   2811 H  HB3    . TRP C 1 49 ? -0.62400  9.51500   24.86300  1.000 39.77960  ?  213 TRP C HB3    1 
ATOM   2812 H  HD1    . TRP C 1 49 ? 1.84800   8.80000   24.92600  1.000 40.13886  ?  213 TRP C HD1    1 
ATOM   2813 H  HE1    . TRP C 1 49 ? 3.19100   7.08000   23.94600  1.000 40.17415  ?  213 TRP C HE1    1 
ATOM   2814 H  HE3    . TRP C 1 49 ? -1.55800  6.56500   22.19800  1.000 39.74595  ?  213 TRP C HE3    1 
ATOM   2815 H  HZ2    . TRP C 1 49 ? 2.84200   4.97700   22.19100  1.000 40.94291  ?  213 TRP C HZ2    1 
ATOM   2816 H  HZ3    . TRP C 1 49 ? -0.96000  4.74600   20.93000  1.000 39.75731  ?  213 TRP C HZ3    1 
ATOM   2817 H  HH2    . TRP C 1 49 ? 1.20300   3.96400   20.92700  1.000 42.50300  ?  213 TRP C HH2    1 
ATOM   2818 N  N      . GLY C 1 50 ? -1.41900  7.59000   27.11800  1.000 39.62819  ?  214 GLY C N      1 
ATOM   2819 C  CA     . GLY C 1 50 ? -0.93600  6.70900   28.18800  1.000 39.28967  ?  214 GLY C CA     1 
ATOM   2820 C  C      . GLY C 1 50 ? -1.99300  5.72500   28.66800  1.000 38.85034  ?  214 GLY C C      1 
ATOM   2821 O  O      . GLY C 1 50 ? -1.69600  4.55000   28.94700  1.000 38.49250  ?  214 GLY C O      1 
ATOM   2822 H  H      . GLY C 1 50 ? -1.51500  8.41400   27.34400  1.000 47.55383  ?  214 GLY C H      1 
ATOM   2823 H  HA2    . GLY C 1 50 ? -0.17300  6.20300   27.86700  1.000 47.14761  ?  214 GLY C HA2    1 
ATOM   2824 H  HA3    . GLY C 1 50 ? -0.65000  7.24500   28.94300  1.000 47.14761  ?  214 GLY C HA3    1 
ATOM   2825 N  N      . ILE C 1 51 ? -3.24900  6.18000   28.75000  1.000 38.85857  ?  215 ILE C N      1 
ATOM   2826 C  CA     . ILE C 1 51 ? -4.35500  5.25600   29.06100  1.000 39.90384  ?  215 ILE C CA     1 
ATOM   2827 C  C      . ILE C 1 51 ? -4.46800  4.19400   27.97300  1.000 42.24837  ?  215 ILE C C      1 
ATOM   2828 O  O      . ILE C 1 51 ? -4.64000  3.00200   28.25700  1.000 44.65312  ?  215 ILE C O      1 
ATOM   2829 C  CB     . ILE C 1 51 ? -5.68400  6.01400   29.20900  1.000 43.18724  ?  215 ILE C CB     1 
ATOM   2830 C  CG1    . ILE C 1 51 ? -5.57700  7.11300   30.26400  1.000 43.03082  ?  215 ILE C CG1    1 
ATOM   2831 C  CG2    . ILE C 1 51 ? -6.81200  5.08200   29.60900  1.000 43.17105  ?  215 ILE C CG2    1 
ATOM   2832 C  CD1    . ILE C 1 51 ? -6.87800  8.06100   30.23000  1.000 48.33796  ?  215 ILE C CD1    1 
ATOM   2833 H  H      . ILE C 1 51 ? -3.48500  6.99800   28.63000  1.000 46.63029  ?  215 ILE C H      1 
ATOM   2834 H  HA     . ILE C 1 51 ? -4.16800  4.80800   29.90100  1.000 47.88460  ?  215 ILE C HA     1 
ATOM   2835 H  HB     . ILE C 1 51 ? -5.90500  6.42200   28.35700  1.000 51.82469  ?  215 ILE C HB     1 
ATOM   2836 H  HG12   . ILE C 1 51 ? -5.51700  6.70900   31.14400  1.000 51.63699  ?  215 ILE C HG12   1 
ATOM   2837 H  HG13   . ILE C 1 51 ? -4.79700  7.66200   30.09200  1.000 51.63699  ?  215 ILE C HG13   1 
ATOM   2838 H  HG21   . ILE C 1 51 ? -7.64200  5.58100   29.64900  1.000 51.80526  ?  215 ILE C HG21   1 
ATOM   2839 H  HG22   . ILE C 1 51 ? -6.89300  4.37400   28.95100  1.000 51.80526  ?  215 ILE C HG22   1 
ATOM   2840 H  HG23   . ILE C 1 51 ? -6.61200  4.70300   30.47900  1.000 51.80526  ?  215 ILE C HG23   1 
ATOM   2841 H  HD11   . ILE C 1 51 ? -6.69100  8.87000   30.73100  1.000 58.00555  ?  215 ILE C HD11   1 
ATOM   2842 H  HD12   . ILE C 1 51 ? -7.08200  8.28300   29.30800  1.000 58.00555  ?  215 ILE C HD12   1 
ATOM   2843 H  HD13   . ILE C 1 51 ? -7.62500  7.59000   30.63000  1.000 58.00555  ?  215 ILE C HD13   1 
ATOM   2844 N  N      . GLN C 1 52 ? -4.33100  4.59800   26.70700  1.000 43.17897  ?  216 GLN C N      1 
ATOM   2845 C  CA     . GLN C 1 52 ? -4.52100  3.61900   25.63600  1.000 41.34625  ?  216 GLN C CA     1 
ATOM   2846 C  C      . GLN C 1 52 ? -3.42900  2.55900   25.66400  1.000 42.57150  ?  216 GLN C C      1 
ATOM   2847 O  O      . GLN C 1 52 ? -3.69000  1.39400   25.35200  1.000 44.96561  ?  216 GLN C O      1 
ATOM   2848 C  CB     . GLN C 1 52 ? -4.56900  4.33200   24.29200  1.000 41.15601  ?  216 GLN C CB     1 
ATOM   2849 C  CG     . GLN C 1 52 ? -4.89000  3.38400   23.12800  0.760 44.50597  ?  216 GLN C CG     1 
ATOM   2850 C  CD     . GLN C 1 52 ? -5.21100  4.12200   21.87600  1.000 42.52808  ?  216 GLN C CD     1 
ATOM   2851 O  OE1    . GLN C 1 52 ? -4.58600  3.87500   20.85300  1.000 48.78729  ?  216 GLN C OE1    1 
ATOM   2852 N  NE2    . GLN C 1 52 ? -6.16500  5.04400   21.93800  1.000 42.08615  ?  216 GLN C NE2    1 
ATOM   2853 H  H      . GLN C 1 52 ? -4.13700  5.39600   26.45100  1.000 51.81477  ?  216 GLN C H      1 
ATOM   2854 H  HA     . GLN C 1 52 ? -5.37200  3.17300   25.76700  1.000 49.61550  ?  216 GLN C HA     1 
ATOM   2855 H  HB2    . GLN C 1 52 ? -5.25500  5.01600   24.32500  1.000 49.38721  ?  216 GLN C HB2    1 
ATOM   2856 H  HB3    . GLN C 1 52 ? -3.70500  4.73700   24.11900  1.000 49.38721  ?  216 GLN C HB3    1 
ATOM   2857 H  HG2    . GLN C 1 52 ? -4.12100  2.81900   22.95600  0.869 53.40716  ?  216 GLN C HG2    1 
ATOM   2858 H  HG3    . GLN C 1 52 ? -5.65800  2.84000   23.36300  0.770 53.40716  ?  216 GLN C HG3    1 
ATOM   2859 H  HE21   . GLN C 1 52 ? -6.57700  5.18800   22.67900  1.000 50.50337  ?  216 GLN C HE21   1 
ATOM   2860 H  HE22   . GLN C 1 52 ? -6.37600  5.49200   21.23500  1.000 50.50337  ?  216 GLN C HE22   1 
ATOM   2861 N  N      . LYS C 1 53 ? -2.20600  2.93000   26.07000  1.000 44.66402  ?  217 LYS C N      1 
ATOM   2862 C  CA     . LYS C 1 53 ? -1.13400  1.93800   26.13000  1.000 39.89874  ?  217 LYS C CA     1 
ATOM   2863 C  C      . LYS C 1 53 ? -1.12300  1.15700   27.44600  1.000 45.93560  ?  217 LYS C C      1 
ATOM   2864 O  O      . LYS C 1 53 ? -0.43000  0.13600   27.54600  1.000 50.71716  ?  217 LYS C O      1 
ATOM   2865 C  CB     . LYS C 1 53 ? 0.23400   2.61500   25.92500  1.000 40.95885  ?  217 LYS C CB     1 
ATOM   2866 C  CG     . LYS C 1 53 ? 0.56100   3.03800   24.44800  1.000 40.73829  ?  217 LYS C CG     1 
ATOM   2867 C  CD     . LYS C 1 53 ? 1.01800   1.87600   23.54800  1.000 35.95604  ?  217 LYS C CD     1 
ATOM   2868 C  CE     . LYS C 1 53 ? 2.35600   1.23800   23.99100  1.000 35.13737  ?  217 LYS C CE     1 
ATOM   2869 N  NZ     . LYS C 1 53 ? 3.49700   2.21200   24.01900  1.000 35.48925  ?  217 LYS C NZ     1 
ATOM   2870 H  H      . LYS C 1 53 ? -1.98000  3.72500   26.30800  1.000 53.59682  ?  217 LYS C H      1 
ATOM   2871 H  HA     . LYS C 1 53 ? -1.25700  1.30000   25.40900  1.000 47.87849  ?  217 LYS C HA     1 
ATOM   2872 H  HB2    . LYS C 1 53 ? 0.26100   3.41800   26.46800  1.000 49.15062  ?  217 LYS C HB2    1 
ATOM   2873 H  HB3    . LYS C 1 53 ? 0.92600   2.00400   26.22000  1.000 49.15062  ?  217 LYS C HB3    1 
ATOM   2874 H  HG2    . LYS C 1 53 ? -0.23500  3.42400   24.05100  1.000 48.88595  ?  217 LYS C HG2    1 
ATOM   2875 H  HG3    . LYS C 1 53 ? 1.27200   3.69700   24.46400  1.000 48.88595  ?  217 LYS C HG3    1 
ATOM   2876 H  HD2    . LYS C 1 53 ? 0.34000   1.18300   23.56400  1.000 43.14725  ?  217 LYS C HD2    1 
ATOM   2877 H  HD3    . LYS C 1 53 ? 1.13100   2.20400   22.64300  1.000 43.14725  ?  217 LYS C HD3    1 
ATOM   2878 H  HE2    . LYS C 1 53 ? 2.25400   0.87000   24.88200  1.000 42.16484  ?  217 LYS C HE2    1 
ATOM   2879 H  HE3    . LYS C 1 53 ? 2.58600   0.53100   23.36800  1.000 42.16484  ?  217 LYS C HE3    1 
ATOM   2880 H  HZ1    . LYS C 1 53 ? 4.24300   1.79900   24.27600  1.000 42.58710  ?  217 LYS C HZ1    1 
ATOM   2881 H  HZ2    . LYS C 1 53 ? 3.62200   2.55700   23.20800  1.000 42.58710  ?  217 LYS C HZ2    1 
ATOM   2882 H  HZ3    . LYS C 1 53 ? 3.32000   2.87100   24.59000  1.000 42.58710  ?  217 LYS C HZ3    1 
ATOM   2883 N  N      . GLY C 1 54 ? -1.85300  1.61900   28.45500  1.000 42.81651  ?  218 GLY C N      1 
ATOM   2884 C  CA     . GLY C 1 54 ? -1.78800  0.97600   29.75400  1.000 45.98027  ?  218 GLY C CA     1 
ATOM   2885 C  C      . GLY C 1 54 ? -0.48000  1.15600   30.49400  1.000 42.74961  ?  218 GLY C C      1 
ATOM   2886 O  O      . GLY C 1 54 ? -0.13300  0.31700   31.33400  1.000 47.97468  ?  218 GLY C O      1 
ATOM   2887 H  H      . GLY C 1 54 ? -2.38500  2.29300   28.41300  1.000 51.37981  ?  218 GLY C H      1 
ATOM   2888 H  HA2    . GLY C 1 54 ? -2.49800  1.32700   30.31400  1.000 55.17632  ?  218 GLY C HA2    1 
ATOM   2889 H  HA3    . GLY C 1 54 ? -1.93800  0.02400   29.64100  1.000 55.17632  ?  218 GLY C HA3    1 
ATOM   2890 N  N      . ASN C 1 55 ? 0.27400   2.21200   30.19600  1.000 40.69663  ?  219 ASN C N      1 
ATOM   2891 C  CA     . ASN C 1 55 ? 1.50900   2.41800   30.92400  1.000 40.59738  ?  219 ASN C CA     1 
ATOM   2892 C  C      . ASN C 1 55 ? 1.24100   2.56500   32.42500  1.000 40.56400  ?  219 ASN C C      1 
ATOM   2893 O  O      . ASN C 1 55 ? 0.12600   2.84100   32.85900  1.000 41.58821  ?  219 ASN C O      1 
ATOM   2894 C  CB     . ASN C 1 55 ? 2.21800   3.66600   30.44200  1.000 43.98284  ?  219 ASN C CB     1 
ATOM   2895 C  CG     . ASN C 1 55 ? 2.57600   3.59300   29.01100  1.000 39.51363  ?  219 ASN C CG     1 
ATOM   2896 O  OD1    . ASN C 1 55 ? 2.96800   2.55100   28.52500  1.000 42.59339  ?  219 ASN C OD1    1 
ATOM   2897 N  ND2    . ASN C 1 55 ? 2.43600   4.70700   28.31900  1.000 35.96622  ?  219 ASN C ND2    1 
ATOM   2898 H  H      . ASN C 1 55 ? 0.09600   2.80200   29.59700  1.000 48.83595  ?  219 ASN C H      1 
ATOM   2899 H  HA     . ASN C 1 55 ? 2.09600   1.65800   30.78800  1.000 48.71686  ?  219 ASN C HA     1 
ATOM   2900 H  HB2    . ASN C 1 55 ? 1.63300   4.42900   30.56800  1.000 52.77941  ?  219 ASN C HB2    1 
ATOM   2901 H  HB3    . ASN C 1 55 ? 3.03500   3.78400   30.95200  1.000 52.77941  ?  219 ASN C HB3    1 
ATOM   2902 H  HD21   . ASN C 1 55 ? 2.63000   4.72000   27.48100  1.000 43.15946  ?  219 ASN C HD21   1 
ATOM   2903 H  HD22   . ASN C 1 55 ? 2.15400   5.42100   28.70600  1.000 43.15946  ?  219 ASN C HD22   1 
ATOM   2904 N  N      . ARG C 1 56 ? 2.30700   2.41800   33.20800  1.000 42.58957  ?  220 ARG C N      1 
ATOM   2905 C  CA     . ARG C 1 56 ? 2.19800   2.42600   34.67100  1.000 47.28034  ?  220 ARG C CA     1 
ATOM   2906 C  C      . ARG C 1 56 ? 2.10800   3.84300   35.20800  1.000 46.26326  ?  220 ARG C C      1 
ATOM   2907 O  O      . ARG C 1 56 ? 1.33800   4.12100   36.13900  1.000 44.18438  ?  220 ARG C O      1 
ATOM   2908 C  CB     . ARG C 1 56 ? 3.40400   1.69900   35.28400  1.000 52.55853  ?  220 ARG C CB     1 
ATOM   2909 C  CG     . ARG C 1 56 ? 3.32700   1.44100   36.76900  0.660 52.55442  ?  220 ARG C CG     1 
ATOM   2910 C  CD     . ARG C 1 56 ? 4.47000   0.52300   37.16000  1.000 62.79604  ?  220 ARG C CD     1 
ATOM   2911 N  NE     . ARG C 1 56 ? 4.22700   -0.86400  36.77400  1.000 67.08131  ?  220 ARG C NE     1 
ATOM   2912 C  CZ     . ARG C 1 56 ? 5.15200   -1.81300  36.75300  0.000 62.00962  ?  220 ARG C CZ     1 
ATOM   2913 N  NH1    . ARG C 1 56 ? 6.42800   -1.54100  36.97400  0.000 61.56571  ?  220 ARG C NH1    1 
ATOM   2914 N  NH2    . ARG C 1 56 ? 4.78700   -3.06500  36.50700  1.000 60.34907  ?  220 ARG C NH2    1 
ATOM   2915 H  H      . ARG C 1 56 ? 3.11000   2.31100   32.91800  1.000 51.10749  ?  220 ARG C H      1 
ATOM   2916 H  HA     . ARG C 1 56 ? 1.39300   1.95200   34.93300  1.000 56.73641  ?  220 ARG C HA     1 
ATOM   2917 H  HB2    . ARG C 1 56 ? 3.49900   0.84000   34.84400  1.000 63.07024  ?  220 ARG C HB2    1 
ATOM   2918 H  HB3    . ARG C 1 56 ? 4.19700   2.23300   35.12300  1.000 63.07024  ?  220 ARG C HB3    1 
ATOM   2919 H  HG2    . ARG C 1 56 ? 3.41700   2.27700   37.25400  0.718 63.06531  ?  220 ARG C HG2    1 
ATOM   2920 H  HG3    . ARG C 1 56 ? 2.48800   1.00500   36.98400  0.693 63.06531  ?  220 ARG C HG3    1 
ATOM   2921 H  HD2    . ARG C 1 56 ? 5.28000   0.82100   36.71800  1.000 75.35525  ?  220 ARG C HD2    1 
ATOM   2922 H  HD3    . ARG C 1 56 ? 4.58500   0.55200   38.12300  1.000 75.35525  ?  220 ARG C HD3    1 
ATOM   2923 H  HE     . ARG C 1 56 ? 3.42700   -1.08000  36.54400  1.000 80.49757  ?  220 ARG C HE     1 
ATOM   2924 H  HH11   . ARG C 1 56 ? 6.67600   -0.73500  37.14000  0.000 73.87885  ?  220 ARG C HH11   1 
ATOM   2925 H  HH12   . ARG C 1 56 ? 7.01100   -2.17300  36.95300  0.000 73.87885  ?  220 ARG C HH12   1 
ATOM   2926 H  HH21   . ARG C 1 56 ? 3.96100   -3.25100  36.35800  1.000 72.41888  ?  220 ARG C HH21   1 
ATOM   2927 H  HH22   . ARG C 1 56 ? 5.37900   -3.68900  36.48300  1.000 72.41888  ?  220 ARG C HH22   1 
ATOM   2928 N  N      . LYS C 1 57 ? 2.88500   4.75200   34.64400  1.000 41.35722  ?  221 LYS C N      1 
ATOM   2929 C  CA     . LYS C 1 57 ? 2.80900   6.13700   35.06800  1.000 43.89576  ?  221 LYS C CA     1 
ATOM   2930 C  C      . LYS C 1 57 ? 1.87700   6.91700   34.12900  1.000 43.52248  ?  221 LYS C C      1 
ATOM   2931 O  O      . LYS C 1 57 ? 1.60400   6.50000   33.00000  1.000 40.56444  ?  221 LYS C O      1 
ATOM   2932 C  CB     . LYS C 1 57 ? 4.21400   6.75200   35.10100  1.000 46.28407  ?  221 LYS C CB     1 
ATOM   2933 C  CG     . LYS C 1 57 ? 5.19000   5.98900   35.98000  1.000 42.18220  ?  221 LYS C CG     1 
ATOM   2934 C  CD     . LYS C 1 57 ? 5.15800   6.53600   37.37500  1.000 49.97578  ?  221 LYS C CD     1 
ATOM   2935 C  CE     . LYS C 1 57 ? 6.08500   7.71900   37.50800  1.000 57.10021  ?  221 LYS C CE     1 
ATOM   2936 N  NZ     . LYS C 1 57 ? 5.47700   8.67700   38.42700  1.000 52.59239  ?  221 LYS C NZ     1 
ATOM   2937 H  H      . LYS C 1 57 ? 3.45800   4.59600   34.02200  1.000 49.62866  ?  221 LYS C H      1 
ATOM   2938 H  HA     . LYS C 1 57 ? 2.44200   6.18300   35.96400  1.000 52.67491  ?  221 LYS C HA     1 
ATOM   2939 H  HB2    . LYS C 1 57 ? 4.57200   6.76300   34.20000  1.000 55.54088  ?  221 LYS C HB2    1 
ATOM   2940 H  HB3    . LYS C 1 57 ? 4.15200   7.65800   35.44100  1.000 55.54088  ?  221 LYS C HB3    1 
ATOM   2941 H  HG2    . LYS C 1 57 ? 4.94500   5.05200   36.01300  1.000 50.61864  ?  221 LYS C HG2    1 
ATOM   2942 H  HG3    . LYS C 1 57 ? 6.08900   6.09100   35.63000  1.000 50.61864  ?  221 LYS C HG3    1 
ATOM   2943 H  HD2    . LYS C 1 57 ? 4.25700   6.82600   37.58800  1.000 59.97093  ?  221 LYS C HD2    1 
ATOM   2944 H  HD3    . LYS C 1 57 ? 5.44800   5.85000   37.99600  1.000 59.97093  ?  221 LYS C HD3    1 
ATOM   2945 H  HE2    . LYS C 1 57 ? 6.93700   7.43200   37.87300  1.000 68.52025  ?  221 LYS C HE2    1 
ATOM   2946 H  HE3    . LYS C 1 57 ? 6.20400   8.14500   36.64500  1.000 68.52025  ?  221 LYS C HE3    1 
ATOM   2947 H  HZ1    . LYS C 1 57 ? 6.00800   9.38500   38.52300  1.000 63.11087  ?  221 LYS C HZ1    1 
ATOM   2948 H  HZ2    . LYS C 1 57 ? 4.69000   8.94600   38.10900  1.000 63.11087  ?  221 LYS C HZ2    1 
ATOM   2949 H  HZ3    . LYS C 1 57 ? 5.35300   8.29800   39.22300  1.000 63.11087  ?  221 LYS C HZ3    1 
ATOM   2950 N  N      . LYS C 1 58 ? 1.42200   8.07100   34.61000  1.000 41.10038  ?  222 LYS C N      1 
ATOM   2951 C  CA     . LYS C 1 58 ? 0.60000   8.95300   33.80800  1.000 40.02730  ?  222 LYS C CA     1 
ATOM   2952 C  C      . LYS C 1 58 ? 1.44200   9.57400   32.69100  1.000 41.32239  ?  222 LYS C C      1 
ATOM   2953 O  O      . LYS C 1 58 ? 2.52800   10.13800  32.93100  1.000 39.54763  ?  222 LYS C O      1 
ATOM   2954 C  CB     . LYS C 1 58 ? -0.01300  10.03100  34.67200  1.000 36.90312  ?  222 LYS C CB     1 
ATOM   2955 C  CG     . LYS C 1 58 ? -0.81600  11.02900  33.96500  1.000 39.32655  ?  222 LYS C CG     1 
ATOM   2956 C  CD     . LYS C 1 58 ? -1.86700  11.71500  34.86100  1.000 45.25533  ?  222 LYS C CD     1 
ATOM   2957 C  CE     . LYS C 1 58 ? -1.87200  13.22400  34.66300  1.000 37.40804  ?  222 LYS C CE     1 
ATOM   2958 N  NZ     . LYS C 1 58 ? -3.26900  13.74000  34.79600  1.000 44.58876  ?  222 LYS C NZ     1 
ATOM   2959 H  H      . LYS C 1 58 ? 1.58000   8.36300   35.40400  1.000 49.32045  ?  222 LYS C H      1 
ATOM   2960 H  HA     . LYS C 1 58 ? -0.11800  8.44200   33.40200  1.000 48.03276  ?  222 LYS C HA     1 
ATOM   2961 H  HB2    . LYS C 1 58 ? -0.58800  9.60500   35.32700  1.000 44.28374  ?  222 LYS C HB2    1 
ATOM   2962 H  HB3    . LYS C 1 58 ? 0.70200   10.50300  35.12700  1.000 44.28374  ?  222 LYS C HB3    1 
ATOM   2963 H  HG2    . LYS C 1 58 ? -0.22300  11.71300  33.61600  1.000 47.19185  ?  222 LYS C HG2    1 
ATOM   2964 H  HG3    . LYS C 1 58 ? -1.28500  10.59500  33.23500  1.000 47.19185  ?  222 LYS C HG3    1 
ATOM   2965 H  HD2    . LYS C 1 58 ? -2.74800  11.37600  34.63700  1.000 54.30639  ?  222 LYS C HD2    1 
ATOM   2966 H  HD3    . LYS C 1 58 ? -1.66400  11.53300  35.79200  1.000 54.30639  ?  222 LYS C HD3    1 
ATOM   2967 H  HE2    . LYS C 1 58 ? -1.32000  13.64400  35.34100  1.000 44.88965  ?  222 LYS C HE2    1 
ATOM   2968 H  HE3    . LYS C 1 58 ? -1.54900  13.44200  33.77500  1.000 44.88965  ?  222 LYS C HE3    1 
ATOM   2969 H  HZ1    . LYS C 1 58 ? -3.27900  14.62300  34.68100  1.000 53.50651  ?  222 LYS C HZ1    1 
ATOM   2970 H  HZ2    . LYS C 1 58 ? -3.79200  13.36300  34.18300  1.000 53.50651  ?  222 LYS C HZ2    1 
ATOM   2971 H  HZ3    . LYS C 1 58 ? -3.58800  13.55000  35.60500  1.000 53.50651  ?  222 LYS C HZ3    1 
ATOM   2972 N  N      . MET C 1 59 ? 0.92200   9.48700   31.47500  1.000 35.57632  ?  223 MET C N      1 
ATOM   2973 C  CA     . MET C 1 59 ? 1.66600   10.00100  30.32500  1.000 32.08942  ?  223 MET C CA     1 
ATOM   2974 C  C      . MET C 1 59 ? 1.58600   11.50900  30.34900  1.000 33.08580  ?  223 MET C C      1 
ATOM   2975 O  O      . MET C 1 59 ? 0.52800   12.09000  30.61500  1.000 37.55697  ?  223 MET C O      1 
ATOM   2976 C  CB     . MET C 1 59 ? 1.10300   9.45300   28.99300  1.000 32.74095  ?  223 MET C CB     1 
ATOM   2977 C  CG     . MET C 1 59 ? 1.74400   10.12400  27.77800  1.000 24.99098  ?  223 MET C CG     1 
ATOM   2978 S  SD     . MET C 1 59 ? 3.53400   9.85000   27.57300  1.000 34.24448  ?  223 MET C SD     1 
ATOM   2979 C  CE     . MET C 1 59 ? 3.66400   8.10800   27.53400  1.000 31.42264  ?  223 MET C CE     1 
ATOM   2980 H  H      . MET C 1 59 ? 0.15700   9.14300   31.28700  1.000 42.69158  ?  223 MET C H      1 
ATOM   2981 H  HA     . MET C 1 59 ? 2.59400   9.72900   30.39700  1.000 38.50730  ?  223 MET C HA     1 
ATOM   2982 H  HB2    . MET C 1 59 ? 1.28000   8.50100   28.94000  1.000 39.28914  ?  223 MET C HB2    1 
ATOM   2983 H  HB3    . MET C 1 59 ? 0.14800   9.61700   28.96100  1.000 39.28914  ?  223 MET C HB3    1 
ATOM   2984 H  HG2    . MET C 1 59 ? 1.31200   9.77500   26.98300  1.000 29.98917  ?  223 MET C HG2    1 
ATOM   2985 H  HG3    . MET C 1 59 ? 1.59700   11.08000  27.82300  1.000 29.98917  ?  223 MET C HG3    1 
ATOM   2986 H  HE1    . MET C 1 59 ? 4.57000   7.86600   27.28700  1.000 37.70716  ?  223 MET C HE1    1 
ATOM   2987 H  HE2    . MET C 1 59 ? 3.45600   7.75700   28.41300  1.000 37.70716  ?  223 MET C HE2    1 
ATOM   2988 H  HE3    . MET C 1 59 ? 3.03900   7.75900   26.87900  1.000 37.70716  ?  223 MET C HE3    1 
ATOM   2989 N  N      . THR C 1 60 ? 2.70900   12.14600  30.11600  1.000 30.75744  ?  224 THR C N      1 
ATOM   2990 C  CA     . THR C 1 60 ? 2.75500   13.58700  30.00400  1.000 28.83102  ?  224 THR C CA     1 
ATOM   2991 C  C      . THR C 1 60 ? 3.19700   14.00200  28.60000  1.000 32.76127  ?  224 THR C C      1 
ATOM   2992 O  O      . THR C 1 60 ? 3.79500   13.22200  27.82400  1.000 32.07182  ?  224 THR C O      1 
ATOM   2993 C  CB     . THR C 1 60 ? 3.75700   14.14500  30.99600  1.000 31.81579  ?  224 THR C CB     1 
ATOM   2994 O  OG1    . THR C 1 60 ? 5.01000   13.62800  30.55400  1.000 31.55942  ?  224 THR C OG1    1 
ATOM   2995 C  CG2    . THR C 1 60 ? 3.48600   13.70200  32.48700  1.000 34.87981  ?  224 THR C CG2    1 
ATOM   2996 H  H      . THR C 1 60 ? 3.47200   11.76300  30.01700  1.000 36.90893  ?  224 THR C H      1 
ATOM   2997 H  HA     . THR C 1 60 ? 1.88300   13.97000  30.18700  1.000 34.59723  ?  224 THR C HA     1 
ATOM   2998 H  HB     . THR C 1 60 ? 3.76400   15.11400  30.95000  1.000 38.17895  ?  224 THR C HB     1 
ATOM   2999 H  HG1    . THR C 1 60 ? 5.62500   13.89600  31.05900  1.000 37.87131  ?  224 THR C HG1    1 
ATOM   3000 H  HG21   . THR C 1 60 ? 4.14000   14.10800  33.07700  1.000 41.85577  ?  224 THR C HG21   1 
ATOM   3001 H  HG22   . THR C 1 60 ? 2.59900   13.98300  32.76000  1.000 41.85577  ?  224 THR C HG22   1 
ATOM   3002 H  HG23   . THR C 1 60 ? 3.54800   12.73700  32.56300  1.000 41.85577  ?  224 THR C HG23   1 
ATOM   3003 N  N      . TYR C 1 61 ? 2.99200   15.26700  28.26500  1.000 33.92604  ?  225 TYR C N      1 
ATOM   3004 C  CA     . TYR C 1 61 ? 3.47700   15.68400  26.95100  1.000 36.05049  ?  225 TYR C CA     1 
ATOM   3005 C  C      . TYR C 1 61 ? 5.00000   15.53900  26.81300  1.000 36.20109  ?  225 TYR C C      1 
ATOM   3006 O  O      . TYR C 1 61 ? 5.48600   15.18600  25.72500  1.000 33.37374  ?  225 TYR C O      1 
ATOM   3007 C  CB     . TYR C 1 61 ? 3.08700   17.11600  26.65300  1.000 34.22515  ?  225 TYR C CB     1 
ATOM   3008 C  CG     . TYR C 1 61 ? 3.64500   17.60200  25.33900  1.000 34.50381  ?  225 TYR C CG     1 
ATOM   3009 C  CD1    . TYR C 1 61 ? 2.95100   17.38600  24.16600  1.000 38.50542  ?  225 TYR C CD1    1 
ATOM   3010 C  CD2    . TYR C 1 61 ? 4.87200   18.26700  25.27100  1.000 37.50298  ?  225 TYR C CD2    1 
ATOM   3011 C  CE1    . TYR C 1 61 ? 3.43800   17.83200  22.94800  1.000 38.15859  ?  225 TYR C CE1    1 
ATOM   3012 C  CE2    . TYR C 1 61 ? 5.37900   18.71200  24.04200  1.000 33.18521  ?  225 TYR C CE2    1 
ATOM   3013 C  CZ     . TYR C 1 61 ? 4.65900   18.48100  22.89500  1.000 37.95671  ?  225 TYR C CZ     1 
ATOM   3014 O  OH     . TYR C 1 61 ? 5.12700   18.92200  21.67700  1.000 48.07794  ?  225 TYR C OH     1 
ATOM   3015 H  H      . TYR C 1 61 ? 2.60300   15.86900  28.74000  1.000 40.71125  ?  225 TYR C H      1 
ATOM   3016 H  HA     . TYR C 1 61 ? 3.06600   15.12100  26.27700  1.000 43.26059  ?  225 TYR C HA     1 
ATOM   3017 H  HB2    . TYR C 1 61 ? 2.12000   17.17900  26.61100  1.000 41.07018  ?  225 TYR C HB2    1 
ATOM   3018 H  HB3    . TYR C 1 61 ? 3.42800   17.69100  27.35600  1.000 41.07018  ?  225 TYR C HB3    1 
ATOM   3019 H  HD1    . TYR C 1 61 ? 2.13100   16.94800  24.19600  1.000 46.20651  ?  225 TYR C HD1    1 
ATOM   3020 H  HD2    . TYR C 1 61 ? 5.35700   18.41800  26.05000  1.000 45.00358  ?  225 TYR C HD2    1 
ATOM   3021 H  HE1    . TYR C 1 61 ? 2.95600   17.67900  22.16800  1.000 45.79031  ?  225 TYR C HE1    1 
ATOM   3022 H  HE2    . TYR C 1 61 ? 6.19500   19.15700  24.00300  1.000 39.82225  ?  225 TYR C HE2    1 
ATOM   3023 H  HH     . TYR C 1 61 ? 5.87200   19.29700  21.77400  1.000 57.69353  ?  225 TYR C HH     1 
ATOM   3024 N  N      . GLN C 1 62 ? 5.79900   15.87600  27.84900  1.000 33.16479  ?  226 GLN C N      1 
ATOM   3025 C  CA     A GLN C 1 62 ? 7.24500   15.76200  27.73600  0.482 33.34827  ?  226 GLN C CA     1 
ATOM   3026 C  CA     B GLN C 1 62 ? 7.24500   15.78100  27.69700  0.518 34.72508  ?  226 GLN C CA     1 
ATOM   3027 C  C      . GLN C 1 62 ? 7.64100   14.35300  27.35200  1.000 32.42571  ?  226 GLN C C      1 
ATOM   3028 O  O      . GLN C 1 62 ? 8.53900   14.13400  26.55600  1.000 31.05451  ?  226 GLN C O      1 
ATOM   3029 C  CB     A GLN C 1 62 ? 7.92500   16.14500  29.06500  0.482 35.65466  ?  226 GLN C CB     1 
ATOM   3030 C  CB     B GLN C 1 62 ? 8.01600   16.31100  28.93000  0.518 35.64553  ?  226 GLN C CB     1 
ATOM   3031 C  CG     A GLN C 1 62 ? 9.37800   15.57000  29.31100  0.482 36.06233  ?  226 GLN C CG     1 
ATOM   3032 C  CG     B GLN C 1 62 ? 9.64800   16.22100  28.88400  0.518 35.94759  ?  226 GLN C CG     1 
ATOM   3033 C  CD     A GLN C 1 62 ? 9.71000   15.38000  30.82600  0.482 38.90497  ?  226 GLN C CD     1 
ATOM   3034 C  CD     B GLN C 1 62 ? 10.48200  17.44200  28.30700  0.518 40.13726  ?  226 GLN C CD     1 
ATOM   3035 O  OE1    A GLN C 1 62 ? 10.29700  14.33600  31.25800  0.482 30.76337  ?  226 GLN C OE1    1 
ATOM   3036 O  OE1    B GLN C 1 62 ? 11.63800  17.26400  27.88000  0.518 36.73967  ?  226 GLN C OE1    1 
ATOM   3037 N  NE2    A GLN C 1 62 ? 9.30300   16.38000  31.63700  0.482 35.75403  ?  226 GLN C NE2    1 
ATOM   3038 N  NE2    B GLN C 1 62 ? 9.91200   18.65500  28.31800  0.518 41.60197  ?  226 GLN C NE2    1 
ATOM   3039 H  H      A GLN C 1 62 ? 5.52200   16.16700  28.60900  0.482 39.79775  ?  226 GLN C H      1 
ATOM   3040 H  H      B GLN C 1 62 ? 5.53000   16.15100  28.61800  0.518 39.79775  ?  226 GLN C H      1 
ATOM   3041 H  HA     A GLN C 1 62 ? 7.56100   16.36600  27.04600  0.482 40.01792  ?  226 GLN C HA     1 
ATOM   3042 H  HA     B GLN C 1 62 ? 7.50300   16.33600  26.94400  0.518 41.67010  ?  226 GLN C HA     1 
ATOM   3043 H  HB2    A GLN C 1 62 ? 7.98900   17.11200  29.10500  0.482 42.78559  ?  226 GLN C HB2    1 
ATOM   3044 H  HB2    B GLN C 1 62 ? 7.78200   17.24400  29.05400  0.518 42.77463  ?  226 GLN C HB2    1 
ATOM   3045 H  HB3    A GLN C 1 62 ? 7.36600   15.83100  29.79300  0.482 42.78559  ?  226 GLN C HB3    1 
ATOM   3046 H  HB3    B GLN C 1 62 ? 7.72600   15.80500  29.70500  0.518 42.77463  ?  226 GLN C HB3    1 
ATOM   3047 H  HG2    A GLN C 1 62 ? 9.48900   14.70500  28.89200  0.482 43.27480  ?  226 GLN C HG2    1 
ATOM   3048 H  HG2    B GLN C 1 62 ? 9.95800   16.08100  29.79300  0.518 43.13710  ?  226 GLN C HG2    1 
ATOM   3049 H  HG3    A GLN C 1 62 ? 10.02400  16.19500  28.94500  0.482 43.27480  ?  226 GLN C HG3    1 
ATOM   3050 H  HG3    B GLN C 1 62 ? 9.88800   15.44700  28.35100  0.518 43.13710  ?  226 GLN C HG3    1 
ATOM   3051 H  HE21   A GLN C 1 62 ? 8.90500   17.06700  31.30700  0.482 42.90484  ?  226 GLN C HE21   1 
ATOM   3052 H  HE21   B GLN C 1 62 ? 9.11400   18.75400  28.62100  0.518 49.92236  ?  226 GLN C HE21   1 
ATOM   3053 H  HE22   A GLN C 1 62 ? 9.45300   16.33600  32.48300  0.482 42.90484  ?  226 GLN C HE22   1 
ATOM   3054 H  HE22   B GLN C 1 62 ? 10.34200  19.33400  28.01300  0.518 49.92236  ?  226 GLN C HE22   1 
ATOM   3055 N  N      . LYS C 1 63 ? 6.95500   13.36700  27.93600  1.000 30.81890  ?  227 LYS C N      1 
ATOM   3056 C  CA     . LYS C 1 63 ? 7.36500   11.99600  27.66600  1.000 30.30488  ?  227 LYS C CA     1 
ATOM   3057 C  C      . LYS C 1 63 ? 6.93500   11.53600  26.28300  1.000 30.94865  ?  227 LYS C C      1 
ATOM   3058 O  O      . LYS C 1 63 ? 7.66200   10.78400  25.60200  1.000 27.05886  ?  227 LYS C O      1 
ATOM   3059 C  CB     . LYS C 1 63 ? 6.80000   11.06100  28.73000  1.000 30.98564  ?  227 LYS C CB     1 
ATOM   3060 C  CG     . LYS C 1 63 ? 7.56500   11.16200  30.09300  1.000 26.09009  ?  227 LYS C CG     1 
ATOM   3061 C  CD     . LYS C 1 63 ? 7.18200   10.00800  31.03600  1.000 25.79383  ?  227 LYS C CD     1 
ATOM   3062 C  CE     . LYS C 1 63 ? 5.69700   10.05000  31.40200  1.000 31.31422  ?  227 LYS C CE     1 
ATOM   3063 N  NZ     . LYS C 1 63 ? 5.32700   9.16700   32.52300  1.000 36.99299  ?  227 LYS C NZ     1 
ATOM   3064 H  H      . LYS C 1 63 ? 6.28300   13.46000  28.46500  1.000 36.98268  ?  227 LYS C H      1 
ATOM   3065 H  HA     . LYS C 1 63 ? 8.33300   11.94400  27.70900  1.000 36.36586  ?  227 LYS C HA     1 
ATOM   3066 H  HB2    . LYS C 1 63 ? 5.87100   11.28900  28.88900  1.000 37.18277  ?  227 LYS C HB2    1 
ATOM   3067 H  HB3    . LYS C 1 63 ? 6.86800   10.14600  28.41500  1.000 37.18277  ?  227 LYS C HB3    1 
ATOM   3068 H  HG2    . LYS C 1 63 ? 8.52000   11.11700  29.92900  1.000 31.30811  ?  227 LYS C HG2    1 
ATOM   3069 H  HG3    . LYS C 1 63 ? 7.33700   11.99900  30.52700  1.000 31.30811  ?  227 LYS C HG3    1 
ATOM   3070 H  HD2    . LYS C 1 63 ? 7.36300   9.16200   30.59700  1.000 30.95259  ?  227 LYS C HD2    1 
ATOM   3071 H  HD3    . LYS C 1 63 ? 7.69900   10.07800  31.85400  1.000 30.95259  ?  227 LYS C HD3    1 
ATOM   3072 H  HE2    . LYS C 1 63 ? 5.46300   10.95800  31.65100  1.000 37.57707  ?  227 LYS C HE2    1 
ATOM   3073 H  HE3    . LYS C 1 63 ? 5.17800   9.77900   30.62900  1.000 37.57707  ?  227 LYS C HE3    1 
ATOM   3074 H  HZ1    . LYS C 1 63 ? 4.45500   9.23300   32.68700  1.000 44.39159  ?  227 LYS C HZ1    1 
ATOM   3075 H  HZ2    . LYS C 1 63 ? 5.52000   8.32200   32.32100  1.000 44.39159  ?  227 LYS C HZ2    1 
ATOM   3076 H  HZ3    . LYS C 1 63 ? 5.77700   9.40000   33.25500  1.000 44.39159  ?  227 LYS C HZ3    1 
ATOM   3077 N  N      . MET C 1 64 ? 5.74100   11.94600  25.88300  1.000 34.04420  ?  228 MET C N      1 
ATOM   3078 C  CA     . MET C 1 64 ? 5.29500   11.65000  24.52600  1.000 33.78408  ?  228 MET C CA     1 
ATOM   3079 C  C      . MET C 1 64 ? 6.18300   12.34200  23.51000  1.000 30.96232  ?  228 MET C C      1 
ATOM   3080 O  O      . MET C 1 64 ? 6.51000   11.73400  22.49000  1.000 32.98994  ?  228 MET C O      1 
ATOM   3081 C  CB     . MET C 1 64 ? 3.82800   12.04500  24.35200  1.000 32.33099  ?  228 MET C CB     1 
ATOM   3082 C  CG     . MET C 1 64 ? 3.19100   11.61000  23.02500  1.000 37.41744  ?  228 MET C CG     1 
ATOM   3083 S  SD     . MET C 1 64 ? 1.45700   12.12000  22.94400  1.000 36.00008  ?  228 MET C SD     1 
ATOM   3084 C  CE     . MET C 1 64 ? 1.74500   13.76500  22.46600  1.000 35.05711  ?  228 MET C CE     1 
ATOM   3085 H  H      . MET C 1 64 ? 5.18000   12.38700  26.36300  1.000 40.85304  ?  228 MET C H      1 
ATOM   3086 H  HA     . MET C 1 64 ? 5.35700   10.69200  24.38500  1.000 40.54089  ?  228 MET C HA     1 
ATOM   3087 H  HB2    . MET C 1 64 ? 3.31300   11.64300  25.06900  1.000 38.79719  ?  228 MET C HB2    1 
ATOM   3088 H  HB3    . MET C 1 64 ? 3.76100   13.01100  24.40700  1.000 38.79719  ?  228 MET C HB3    1 
ATOM   3089 H  HG2    . MET C 1 64 ? 3.66700   12.02400  22.28800  1.000 44.90093  ?  228 MET C HG2    1 
ATOM   3090 H  HG3    . MET C 1 64 ? 3.22900   10.64400  22.95100  1.000 44.90093  ?  228 MET C HG3    1 
ATOM   3091 H  HE1    . MET C 1 64 ? 0.89200   14.21100  22.34200  1.000 42.06854  ?  228 MET C HE1    1 
ATOM   3092 H  HE2    . MET C 1 64 ? 2.25400   14.21200  23.16000  1.000 42.06854  ?  228 MET C HE2    1 
ATOM   3093 H  HE3    . MET C 1 64 ? 2.24400   13.76900  21.63400  1.000 42.06854  ?  228 MET C HE3    1 
ATOM   3094 N  N      . ALA C 1 65 ? 6.59500   13.58900  23.77500  1.000 28.48707  ?  229 ALA C N      1 
ATOM   3095 C  CA     . ALA C 1 65 ? 7.53900   14.28700  22.90800  1.000 26.81536  ?  229 ALA C CA     1 
ATOM   3096 C  C      . ALA C 1 65 ? 8.89100   13.59200  22.87900  1.000 32.49807  ?  229 ALA C C      1 
ATOM   3097 O  O      . ALA C 1 65 ? 9.53700   13.52100  21.81900  1.000 33.14554  ?  229 ALA C O      1 
ATOM   3098 C  CB     . ALA C 1 65 ? 7.74300   15.74900  23.29900  1.000 28.99574  ?  229 ALA C CB     1 
ATOM   3099 H  H      . ALA C 1 65 ? 6.33900   14.05000  24.45400  1.000 34.18448  ?  229 ALA C H      1 
ATOM   3100 H  HA     . ALA C 1 65 ? 7.18800   14.27600  22.00400  1.000 32.17843  ?  229 ALA C HA     1 
ATOM   3101 H  HB1    . ALA C 1 65 ? 8.37800   16.15300  22.68700  1.000 34.79489  ?  229 ALA C HB1    1 
ATOM   3102 H  HB2    . ALA C 1 65 ? 6.89200   16.21100  23.24600  1.000 34.79489  ?  229 ALA C HB2    1 
ATOM   3103 H  HB3    . ALA C 1 65 ? 8.08600   15.78800  24.20600  1.000 34.79489  ?  229 ALA C HB3    1 
ATOM   3104 N  N      . ARG C 1 66 ? 9.32100   13.02400  24.01100  1.000 30.15561  ?  230 ARG C N      1 
ATOM   3105 C  CA     . ARG C 1 66 ? 10.51800  12.18600  23.97800  1.000 32.04711  ?  230 ARG C CA     1 
ATOM   3106 C  C      . ARG C 1 66 ? 10.38200  11.06700  22.95200  1.000 32.83304  ?  230 ARG C C      1 
ATOM   3107 O  O      . ARG C 1 66 ? 11.31500  10.79300  22.15900  1.000 32.69255  ?  230 ARG C O      1 
ATOM   3108 C  CB     . ARG C 1 66 ? 10.79600  11.58900  25.34900  1.000 36.35118  ?  230 ARG C CB     1 
ATOM   3109 C  CG     . ARG C 1 66 ? 12.06700  10.76300  25.34100  1.000 37.17090  ?  230 ARG C CG     1 
ATOM   3110 C  CD     . ARG C 1 66 ? 13.28800  11.64700  25.20700  1.000 38.17092  ?  230 ARG C CD     1 
ATOM   3111 N  NE     . ARG C 1 66 ? 14.51200  10.87300  25.12500  1.000 31.85174  ?  230 ARG C NE     1 
ATOM   3112 C  CZ     . ARG C 1 66 ? 14.97000  10.38100  23.98900  1.000 44.80824  ?  230 ARG C CZ     1 
ATOM   3113 N  NH1    . ARG C 1 66 ? 14.27700  10.48100  22.87800  1.000 37.40175  ?  230 ARG C NH1    1 
ATOM   3114 N  NH2    . ARG C 1 66 ? 16.16100  9.78700   23.97000  1.000 46.86775  ?  230 ARG C NH2    1 
ATOM   3115 H  H      . ARG C 1 66 ? 8.95100   13.10500  24.78300  1.000 36.18673  ?  230 ARG C H      1 
ATOM   3116 H  HA     . ARG C 1 66 ? 11.27200  12.73800  23.72200  1.000 38.45654  ?  230 ARG C HA     1 
ATOM   3117 H  HB2    . ARG C 1 66 ? 10.90100  12.30400  25.99500  1.000 43.62141  ?  230 ARG C HB2    1 
ATOM   3118 H  HB3    . ARG C 1 66 ? 10.06100  11.01100  25.60300  1.000 43.62141  ?  230 ARG C HB3    1 
ATOM   3119 H  HG2    . ARG C 1 66 ? 12.13600  10.28900  26.18400  1.000 44.60508  ?  230 ARG C HG2    1 
ATOM   3120 H  HG3    . ARG C 1 66 ? 12.06200  10.13100  24.60700  1.000 44.60508  ?  230 ARG C HG3    1 
ATOM   3121 H  HD2    . ARG C 1 66 ? 13.21800  12.15700  24.39000  1.000 45.80510  ?  230 ARG C HD2    1 
ATOM   3122 H  HD3    . ARG C 1 66 ? 13.34700  12.23800  25.97400  1.000 45.80510  ?  230 ARG C HD3    1 
ATOM   3123 H  HE     . ARG C 1 66 ? 14.85000  10.57500  25.85800  1.000 38.22208  ?  230 ARG C HE     1 
ATOM   3124 H  HH11   . ARG C 1 66 ? 13.50900  10.86600  22.87400  1.000 44.88210  ?  230 ARG C HH11   1 
ATOM   3125 H  HH12   . ARG C 1 66 ? 14.59300  10.15300  22.14800  1.000 44.88210  ?  230 ARG C HH12   1 
ATOM   3126 H  HH21   . ARG C 1 66 ? 16.61800  9.71700   24.69500  1.000 56.24129  ?  230 ARG C HH21   1 
ATOM   3127 H  HH22   . ARG C 1 66 ? 16.46600  9.45800   23.23600  1.000 56.24129  ?  230 ARG C HH22   1 
ATOM   3128 N  N      . ALA C 1 67 ? 9.23800   10.36400  22.98000  1.000 28.80131  ?  231 ALA C N      1 
ATOM   3129 C  CA     . ALA C 1 67 ? 9.03400   9.30200   22.00700  1.000 31.00927  ?  231 ALA C CA     1 
ATOM   3130 C  C      . ALA C 1 67 ? 8.91200   9.86700   20.57800  1.000 33.13404  ?  231 ALA C C      1 
ATOM   3131 O  O      . ALA C 1 67 ? 9.39700   9.27500   19.61900  1.000 34.00641  ?  231 ALA C O      1 
ATOM   3132 C  CB     . ALA C 1 67 ? 7.79800   8.50100   22.35800  1.000 26.51835  ?  231 ALA C CB     1 
ATOM   3133 H  H      . ALA C 1 67 ? 8.59200   10.48300  23.53500  1.000 34.56157  ?  231 ALA C H      1 
ATOM   3134 H  HA     . ALA C 1 67 ? 9.79600   8.70300   22.02900  1.000 37.21113  ?  231 ALA C HA     1 
ATOM   3135 H  HB1    . ALA C 1 67 ? 7.67400   7.80600   21.69300  1.000 31.82202  ?  231 ALA C HB1    1 
ATOM   3136 H  HB2    . ALA C 1 67 ? 7.91800   8.10400   23.23500  1.000 31.82202  ?  231 ALA C HB2    1 
ATOM   3137 H  HB3    . ALA C 1 67 ? 7.03000   9.09300   22.36400  1.000 31.82202  ?  231 ALA C HB3    1 
ATOM   3138 N  N      . LEU C 1 68 ? 8.29800   11.01800  20.42200  1.000 33.25752  ?  232 LEU C N      1 
ATOM   3139 C  CA     . LEU C 1 68 ? 8.22700   11.59800  19.08900  1.000 35.19901  ?  232 LEU C CA     1 
ATOM   3140 C  C      . LEU C 1 68 ? 9.61800   11.86000  18.53600  1.000 39.88101  ?  232 LEU C C      1 
ATOM   3141 O  O      . LEU C 1 68 ? 9.86700   11.62200  17.35600  1.000 37.21093  ?  232 LEU C O      1 
ATOM   3142 C  CB     . LEU C 1 68 ? 7.44800   12.91200  19.09900  1.000 36.52968  ?  232 LEU C CB     1 
ATOM   3143 C  CG     . LEU C 1 68 ? 5.93700   12.75400  19.05300  1.000 32.88568  ?  232 LEU C CG     1 
ATOM   3144 C  CD1    . LEU C 1 68 ? 5.28200   14.10500  18.88800  1.000 35.32606  ?  232 LEU C CD1    1 
ATOM   3145 C  CD2    . LEU C 1 68 ? 5.48600   11.78300  17.99000  1.000 35.40530  ?  232 LEU C CD2    1 
ATOM   3146 H  H      . LEU C 1 68 ? 7.92300   11.47700  21.04600  1.000 39.90902  ?  232 LEU C H      1 
ATOM   3147 H  HA     . LEU C 1 68 ? 7.79800   10.96700  18.49400  1.000 42.23882  ?  232 LEU C HA     1 
ATOM   3148 H  HB2    . LEU C 1 68 ? 7.66800   13.39600  19.91000  1.000 43.83562  ?  232 LEU C HB2    1 
ATOM   3149 H  HB3    . LEU C 1 68 ? 7.71200   13.43400  18.32500  1.000 43.83562  ?  232 LEU C HB3    1 
ATOM   3150 H  HG     . LEU C 1 68 ? 5.64500   12.39800  19.90700  1.000 39.46282  ?  232 LEU C HG     1 
ATOM   3151 H  HD11   . LEU C 1 68 ? 4.31900   13.99100  18.88700  1.000 42.39127  ?  232 LEU C HD11   1 
ATOM   3152 H  HD12   . LEU C 1 68 ? 5.54700   14.67600  19.62600  1.000 42.39127  ?  232 LEU C HD12   1 
ATOM   3153 H  HD13   . LEU C 1 68 ? 5.57100   14.49500  18.04800  1.000 42.39127  ?  232 LEU C HD13   1 
ATOM   3154 H  HD21   . LEU C 1 68 ? 4.55600   11.95900  17.77600  1.000 42.48636  ?  232 LEU C HD21   1 
ATOM   3155 H  HD22   . LEU C 1 68 ? 6.03600   11.90300  17.20000  1.000 42.48636  ?  232 LEU C HD22   1 
ATOM   3156 H  HD23   . LEU C 1 68 ? 5.58300   10.87800  18.32500  1.000 42.48636  ?  232 LEU C HD23   1 
ATOM   3157 N  N      . ARG C 1 69 ? 10.53400  12.36200  19.37400  1.000 35.40142  ?  233 ARG C N      1 
ATOM   3158 C  CA     . ARG C 1 69 ? 11.86200  12.71200  18.87600  1.000 36.19969  ?  233 ARG C CA     1 
ATOM   3159 C  C      . ARG C 1 69 ? 12.61000  11.47500  18.42300  1.000 38.18620  ?  233 ARG C C      1 
ATOM   3160 O  O      . ARG C 1 69 ? 13.40500  11.53500  17.47500  1.000 39.27654  ?  233 ARG C O      1 
ATOM   3161 C  CB     . ARG C 1 69 ? 12.70500  13.42900  19.94600  1.000 39.20437  ?  233 ARG C CB     1 
ATOM   3162 C  CG     . ARG C 1 69 ? 12.37800  14.92000  20.06500  1.000 42.43580  ?  233 ARG C CG     1 
ATOM   3163 C  CD     . ARG C 1 69 ? 13.42600  15.64400  20.89100  1.000 42.20804  ?  233 ARG C CD     1 
ATOM   3164 N  NE     . ARG C 1 69 ? 13.60700  15.02900  22.20300  1.000 41.70714  ?  233 ARG C NE     1 
ATOM   3165 C  CZ     . ARG C 1 69 ? 12.83500  15.25400  23.25500  1.000 37.82100  ?  233 ARG C CZ     1 
ATOM   3166 N  NH1    . ARG C 1 69 ? 11.82200  16.11700  23.21100  1.000 36.22556  ?  233 ARG C NH1    1 
ATOM   3167 N  NH2    . ARG C 1 69 ? 13.08300  14.61200  24.37800  1.000 40.06937  ?  233 ARG C NH2    1 
ATOM   3168 H  H      . ARG C 1 69 ? 10.41300  12.50500  20.21300  1.000 42.48170  ?  233 ARG C H      1 
ATOM   3169 H  HA     . ARG C 1 69 ? 11.77000  13.30600  18.11500  1.000 43.43963  ?  233 ARG C HA     1 
ATOM   3170 H  HB2    . ARG C 1 69 ? 12.53800  13.01600  20.80800  1.000 47.04525  ?  233 ARG C HB2    1 
ATOM   3171 H  HB3    . ARG C 1 69 ? 13.64400  13.34600  19.71600  1.000 47.04525  ?  233 ARG C HB3    1 
ATOM   3172 H  HG2    . ARG C 1 69 ? 12.35900  15.31700  19.18000  1.000 50.92296  ?  233 ARG C HG2    1 
ATOM   3173 H  HG3    . ARG C 1 69 ? 11.51800  15.02700  20.50100  1.000 50.92296  ?  233 ARG C HG3    1 
ATOM   3174 H  HD2    . ARG C 1 69 ? 14.27600  15.61400  20.42400  1.000 50.64965  ?  233 ARG C HD2    1 
ATOM   3175 H  HD3    . ARG C 1 69 ? 13.15000  16.56500  21.02200  1.000 50.64965  ?  233 ARG C HD3    1 
ATOM   3176 H  HE     . ARG C 1 69 ? 14.26300  14.48100  22.29900  1.000 50.04857  ?  233 ARG C HE     1 
ATOM   3177 H  HH11   . ARG C 1 69 ? 11.64600  16.54100  22.48400  1.000 43.47067  ?  233 ARG C HH11   1 
ATOM   3178 H  HH12   . ARG C 1 69 ? 11.33700  16.24500  23.91000  1.000 43.47067  ?  233 ARG C HH12   1 
ATOM   3179 H  HH21   . ARG C 1 69 ? 13.73900  14.05900  24.41800  1.000 48.08325  ?  233 ARG C HH21   1 
ATOM   3180 H  HH22   . ARG C 1 69 ? 12.59400  14.75200  25.07100  1.000 48.08325  ?  233 ARG C HH22   1 
ATOM   3181 N  N      . ASN C 1 70 ? 12.32400  10.33100  19.04100  1.000 39.34976  ?  234 ASN C N      1 
ATOM   3182 C  CA     . ASN C 1 70 ? 12.93800  9.14000   18.46600  1.000 41.93931  ?  234 ASN C CA     1 
ATOM   3183 C  C      . ASN C 1 70 ? 12.53800  8.88100   17.00500  1.000 40.46086  ?  234 ASN C C      1 
ATOM   3184 O  O      . ASN C 1 70 ? 13.26600  8.17700   16.30400  1.000 41.96659  ?  234 ASN C O      1 
ATOM   3185 C  CB     . ASN C 1 70 ? 12.59500  7.93000   19.29500  1.000 40.34728  ?  234 ASN C CB     1 
ATOM   3186 C  CG     . ASN C 1 70 ? 13.48000  7.79800   20.46800  1.000 42.44127  ?  234 ASN C CG     1 
ATOM   3187 O  OD1    . ASN C 1 70 ? 14.47900  8.52900   20.61700  1.000 44.01601  ?  234 ASN C OD1    1 
ATOM   3188 N  ND2    . ASN C 1 70 ? 13.13800  6.85400   21.33500  1.000 44.41174  ?  234 ASN C ND2    1 
ATOM   3189 H  H      . ASN C 1 70 ? 11.82400  10.22000  19.73200  1.000 47.21971  ?  234 ASN C H      1 
ATOM   3190 H  HA     . ASN C 1 70 ? 13.90100  9.25100   18.48200  1.000 50.32717  ?  234 ASN C HA     1 
ATOM   3191 H  HB2    . ASN C 1 70 ? 11.68200  8.00900   19.61200  1.000 48.41673  ?  234 ASN C HB2    1 
ATOM   3192 H  HB3    . ASN C 1 70 ? 12.69200  7.13300   18.75100  1.000 48.41673  ?  234 ASN C HB3    1 
ATOM   3193 H  HD21   . ASN C 1 70 ? 13.61300  6.72500   22.04000  1.000 53.29409  ?  234 ASN C HD21   1 
ATOM   3194 H  HD22   . ASN C 1 70 ? 12.44000  6.37200   21.19200  1.000 53.29409  ?  234 ASN C HD22   1 
ATOM   3195 N  N      . TYR C 1 71 ? 11.39100  9.39300   16.53700  1.000 35.46937  ?  235 TYR C N      1 
ATOM   3196 C  CA     . TYR C 1 71 ? 10.99300  9.10800   15.17400  1.000 39.17567  ?  235 TYR C CA     1 
ATOM   3197 C  C      . TYR C 1 71 ? 11.87500  9.82500   14.17800  1.000 42.19709  ?  235 TYR C C      1 
ATOM   3198 O  O      . TYR C 1 71 ? 11.84500  9.47000   12.98600  1.000 45.86025  ?  235 TYR C O      1 
ATOM   3199 C  CB     . TYR C 1 71 ? 9.53500   9.50000   14.91500  1.000 41.16125  ?  235 TYR C CB     1 
ATOM   3200 C  CG     . TYR C 1 71 ? 8.49400   8.53300   15.44900  1.000 37.96013  ?  235 TYR C CG     1 
ATOM   3201 C  CD1    . TYR C 1 71 ? 8.60600   7.16300   15.27100  1.000 39.37578  ?  235 TYR C CD1    1 
ATOM   3202 C  CD2    . TYR C 1 71 ? 7.35900   9.00800   16.08600  1.000 34.77780  ?  235 TYR C CD2    1 
ATOM   3203 C  CE1    . TYR C 1 71 ? 7.62600   6.27800   15.77500  1.000 39.92196  ?  235 TYR C CE1    1 
ATOM   3204 C  CE2    . TYR C 1 71 ? 6.36800   8.15000   16.52800  1.000 35.69830  ?  235 TYR C CE2    1 
ATOM   3205 C  CZ     . TYR C 1 71 ? 6.50700   6.79000   16.41200  1.000 35.61206  ?  235 TYR C CZ     1 
ATOM   3206 O  OH     . TYR C 1 71 ? 5.46500   5.98900   16.89300  1.000 38.13035  ?  235 TYR C OH     1 
ATOM   3207 H  H      . TYR C 1 71 ? 10.84800  9.89100   16.98100  1.000 42.56325  ?  235 TYR C H      1 
ATOM   3208 H  HA     . TYR C 1 71 ? 11.08600  8.15600   15.01400  1.000 47.01081  ?  235 TYR C HA     1 
ATOM   3209 H  HB2    . TYR C 1 71 ? 9.37000   10.36200  15.32700  1.000 49.39350  ?  235 TYR C HB2    1 
ATOM   3210 H  HB3    . TYR C 1 71 ? 9.40200   9.56900   13.95700  1.000 49.39350  ?  235 TYR C HB3    1 
ATOM   3211 H  HD1    . TYR C 1 71 ? 9.36400   6.81700   14.85800  1.000 47.25093  ?  235 TYR C HD1    1 
ATOM   3212 H  HD2    . TYR C 1 71 ? 7.24600   9.92500   16.18900  1.000 41.73336  ?  235 TYR C HD2    1 
ATOM   3213 H  HE1    . TYR C 1 71 ? 7.71800   5.36000   15.65500  1.000 47.90635  ?  235 TYR C HE1    1 
ATOM   3214 H  HE2    . TYR C 1 71 ? 5.62600   8.49800   16.96800  1.000 42.83796  ?  235 TYR C HE2    1 
ATOM   3215 H  HH     . TYR C 1 71 ? 5.62200   5.18100   16.72500  1.000 45.75642  ?  235 TYR C HH     1 
ATOM   3216 N  N      . GLY C 1 72 ? 12.59900  10.86000  14.61900  1.000 38.04612  ?  236 GLY C N      1 
ATOM   3217 C  CA     . GLY C 1 72 ? 13.47100  11.63200  13.73700  1.000 44.33214  ?  236 GLY C CA     1 
ATOM   3218 C  C      . GLY C 1 72 ? 14.62900  10.83200  13.17000  1.000 45.58916  ?  236 GLY C C      1 
ATOM   3219 O  O      . GLY C 1 72 ? 15.18800  11.21200  12.12500  1.000 56.77379  ?  236 GLY C O      1 
ATOM   3220 H  H      . GLY C 1 72 ? 12.60000  11.13600  15.43300  1.000 45.65534  ?  236 GLY C H      1 
ATOM   3221 H  HA2    . GLY C 1 72 ? 12.94900  11.97700  12.99500  1.000 53.19857  ?  236 GLY C HA2    1 
ATOM   3222 H  HA3    . GLY C 1 72 ? 13.83500  12.38500  14.22800  1.000 53.19857  ?  236 GLY C HA3    1 
ATOM   3223 N  N      . LYS C 1 73 ? 14.97400  9.72300   13.81400  1.000 45.18775  ?  237 LYS C N      1 
ATOM   3224 C  CA     . LYS C 1 73 ? 16.07200  8.83700   13.37600  1.000 52.77165  ?  237 LYS C CA     1 
ATOM   3225 C  C      . LYS C 1 73 ? 15.57400  7.90400   12.28500  1.000 51.15982  ?  237 LYS C C      1 
ATOM   3226 O  O      . LYS C 1 73 ? 16.36300  7.59600   11.38100  0.777 53.73708  ?  237 LYS C O      1 
ATOM   3227 C  CB     . LYS C 1 73 ? 16.51600  7.95600   14.53800  1.000 47.96476  ?  237 LYS C CB     1 
ATOM   3228 C  CG     . LYS C 1 73 ? 17.08600  8.68700   15.74300  0.000 51.04931  ?  237 LYS C CG     1 
ATOM   3229 C  CD     . LYS C 1 73 ? 17.35700  7.78100   16.92500  1.000 57.30927  ?  237 LYS C CD     1 
ATOM   3230 C  CE     . LYS C 1 73 ? 18.27300  6.61400   16.61900  1.000 60.42441  ?  237 LYS C CE     1 
ATOM   3231 N  NZ     . LYS C 1 73 ? 19.59500  7.05700   16.11500  0.000 55.21680  ?  237 LYS C NZ     1 
ATOM   3232 H  H      . LYS C 1 73 ? 14.58200  9.44700   14.52800  1.000 54.22530  ?  237 LYS C H      1 
ATOM   3233 H  HA     . LYS C 1 73 ? 16.82400  9.35400   13.04900  1.000 63.32598  ?  237 LYS C HA     1 
ATOM   3234 H  HB2    . LYS C 1 73 ? 15.75100  7.44400   14.84400  1.000 57.55772  ?  237 LYS C HB2    1 
ATOM   3235 H  HB3    . LYS C 1 73 ? 17.20100  7.35100   14.21300  1.000 57.55772  ?  237 LYS C HB3    1 
ATOM   3236 H  HG2    . LYS C 1 73 ? 17.92400  9.10400   15.48900  0.000 61.25917  ?  237 LYS C HG2    1 
ATOM   3237 H  HG3    . LYS C 1 73 ? 16.45300  9.36500   16.02700  0.000 61.25917  ?  237 LYS C HG3    1 
ATOM   3238 H  HD2    . LYS C 1 73 ? 17.77100  8.30400   17.62900  1.000 68.77113  ?  237 LYS C HD2    1 
ATOM   3239 H  HD3    . LYS C 1 73 ? 16.51400  7.41900   17.23900  1.000 68.77113  ?  237 LYS C HD3    1 
ATOM   3240 H  HE2    . LYS C 1 73 ? 18.41800  6.10500   17.43200  1.000 72.50929  ?  237 LYS C HE2    1 
ATOM   3241 H  HE3    . LYS C 1 73 ? 17.86300  6.05100   15.94400  1.000 72.50929  ?  237 LYS C HE3    1 
ATOM   3242 H  HZ1    . LYS C 1 73 ? 20.10900  6.35000   15.94800  0.000 66.26016  ?  237 LYS C HZ1    1 
ATOM   3243 H  HZ2    . LYS C 1 73 ? 19.49300  7.52400   15.36500  0.000 66.26016  ?  237 LYS C HZ2    1 
ATOM   3244 H  HZ3    . LYS C 1 73 ? 19.99600  7.56900   16.72300  0.000 66.26016  ?  237 LYS C HZ3    1 
ATOM   3245 N  N      . THR C 1 74 ? 14.32800  7.46900   12.37900  1.000 52.10001  ?  238 THR C N      1 
ATOM   3246 C  CA     . THR C 1 74 ? 13.72200  6.48900   11.45300  1.000 51.24527  ?  238 THR C CA     1 
ATOM   3247 C  C      . THR C 1 74 ? 13.02000  7.23600   10.31900  1.000 50.94580  ?  238 THR C C      1 
ATOM   3248 O  O      . THR C 1 74 ? 12.91700  6.66400   9.23500   1.000 57.96689  ?  238 THR C O      1 
ATOM   3249 C  CB     . THR C 1 74 ? 12.82800  5.58700   12.30200  1.000 52.62395  ?  238 THR C CB     1 
ATOM   3250 O  OG1    . THR C 1 74 ? 13.57800  5.19700   13.44900  1.000 64.42505  ?  238 THR C OG1    1 
ATOM   3251 C  CG2    . THR C 1 74 ? 12.35600  4.36300   11.55400  1.000 64.14028  ?  238 THR C CG2    1 
ATOM   3252 H  H      . THR C 1 74 ? 13.78300  7.73000   12.99100  1.000 62.52001  ?  238 THR C H      1 
ATOM   3253 H  HA     . THR C 1 74 ? 14.42200  5.94100   11.06500  1.000 61.49433  ?  238 THR C HA     1 
ATOM   3254 H  HB     . THR C 1 74 ? 12.05300  6.08800   12.59100  1.000 63.14874  ?  238 THR C HB     1 
ATOM   3255 H  HG1    . THR C 1 74 ? 13.11400  4.69800   13.94000  1.000 77.31005  ?  238 THR C HG1    1 
ATOM   3256 H  HG21   . THR C 1 74 ? 11.79400  3.82000   12.12800  1.000 76.96834  ?  238 THR C HG21   1 
ATOM   3257 H  HG22   . THR C 1 74 ? 11.84600  4.62800   10.77300  1.000 76.96834  ?  238 THR C HG22   1 
ATOM   3258 H  HG23   . THR C 1 74 ? 13.11800  3.83500   11.26900  1.000 76.96834  ?  238 THR C HG23   1 
ATOM   3259 N  N      . GLY C 1 75 ? 12.55800  8.45300   10.56500  1.000 49.57366  ?  239 GLY C N      1 
ATOM   3260 C  CA     . GLY C 1 75 ? 11.94700  9.31100   9.53700   1.000 48.18970  ?  239 GLY C CA     1 
ATOM   3261 C  C      . GLY C 1 75 ? 10.43900  9.44300   9.59300   1.000 41.32831  ?  239 GLY C C      1 
ATOM   3262 O  O      . GLY C 1 75 ? 9.96200   10.35600  8.94500   1.000 46.54333  ?  239 GLY C O      1 
ATOM   3263 H  H      . GLY C 1 75 ? 12.58300  8.82200   11.34100  1.000 59.48839  ?  239 GLY C H      1 
ATOM   3264 H  HA2    . GLY C 1 75 ? 12.32400  10.20200  9.61200   1.000 57.82764  ?  239 GLY C HA2    1 
ATOM   3265 H  HA3    . GLY C 1 75 ? 12.18000  8.96400   8.66200   1.000 57.82764  ?  239 GLY C HA3    1 
ATOM   3266 N  N      . GLU C 1 76 ? 9.70500   8.64600   10.36500  1.000 42.60859  ?  240 GLU C N      1 
ATOM   3267 C  CA     . GLU C 1 76 ? 8.24000   8.69300   10.28200  1.000 46.93473  ?  240 GLU C CA     1 
ATOM   3268 C  C      . GLU C 1 76 ? 7.68800   10.05400  10.66100  1.000 45.10715  ?  240 GLU C C      1 
ATOM   3269 O  O      . GLU C 1 76 ? 6.64100   10.46200  10.13800  1.000 41.28477  ?  240 GLU C O      1 
ATOM   3270 C  CB     . GLU C 1 76 ? 7.58600   7.64300   11.16800  1.000 44.39708  ?  240 GLU C CB     1 
ATOM   3271 C  CG     . GLU C 1 76 ? 8.04900   6.25400   10.89700  1.000 49.54606  ?  240 GLU C CG     1 
ATOM   3272 C  CD     . GLU C 1 76 ? 9.20200   5.87400   11.79500  1.000 53.12465  ?  240 GLU C CD     1 
ATOM   3273 O  OE1    . GLU C 1 76 ? 9.92300   6.83100   12.21300  1.000 54.48763  ?  240 GLU C OE1    1 
ATOM   3274 O  OE2    . GLU C 1 76 ? 9.36700   4.64600   12.08100  1.000 56.61805  -1 240 GLU C OE2    1 
ATOM   3275 H  H      . GLU C 1 76 ? 10.01900  8.08400   10.93400  1.000 51.13031  ?  240 GLU C H      1 
ATOM   3276 H  HA     . GLU C 1 76 ? 7.97500   8.51300   9.36700   1.000 56.32168  ?  240 GLU C HA     1 
ATOM   3277 H  HB2    . GLU C 1 76 ? 7.78900   7.84900   12.09400  1.000 53.27650  ?  240 GLU C HB2    1 
ATOM   3278 H  HB3    . GLU C 1 76 ? 6.62700   7.66800   11.03700  1.000 53.27650  ?  240 GLU C HB3    1 
ATOM   3279 H  HG2    . GLU C 1 76 ? 7.32000   5.63500   11.06000  1.000 59.45527  ?  240 GLU C HG2    1 
ATOM   3280 H  HG3    . GLU C 1 76 ? 8.34600   6.18900   9.97600   1.000 59.45527  ?  240 GLU C HG3    1 
ATOM   3281 N  N      . VAL C 1 77 ? 8.36700   10.77400  11.54900  1.000 39.93343  ?  241 VAL C N      1 
ATOM   3282 C  CA     . VAL C 1 77 ? 7.84700   12.03400  12.08000  1.000 38.90585  ?  241 VAL C CA     1 
ATOM   3283 C  C      . VAL C 1 77 ? 9.04300   12.93800  12.28600  1.000 40.63812  ?  241 VAL C C      1 
ATOM   3284 O  O      . VAL C 1 77 ? 10.02300  12.55700  12.94900  1.000 35.76905  ?  241 VAL C O      1 
ATOM   3285 C  CB     . VAL C 1 77 ? 7.07700   11.84700  13.42400  1.000 40.25938  ?  241 VAL C CB     1 
ATOM   3286 C  CG1    . VAL C 1 77 ? 6.53700   13.16800  13.96500  1.000 35.07559  ?  241 VAL C CG1    1 
ATOM   3287 C  CG2    . VAL C 1 77 ? 5.93500   10.87800  13.27800  1.000 38.68408  ?  241 VAL C CG2    1 
ATOM   3288 H  H      . VAL C 1 77 ? 9.13700   10.55400  11.86300  1.000 47.92012  ?  241 VAL C H      1 
ATOM   3289 H  HA     . VAL C 1 77 ? 7.25300   12.44500  11.43300  1.000 46.68702  ?  241 VAL C HA     1 
ATOM   3290 H  HB     . VAL C 1 77 ? 7.68800   11.48500  14.08500  1.000 48.31125  ?  241 VAL C HB     1 
ATOM   3291 H  HG11   . VAL C 1 77 ? 5.99100   12.98900  14.74600  1.000 42.09071  ?  241 VAL C HG11   1 
ATOM   3292 H  HG12   . VAL C 1 77 ? 7.28200   13.74000  14.20800  1.000 42.09071  ?  241 VAL C HG12   1 
ATOM   3293 H  HG13   . VAL C 1 77 ? 6.00100   13.59400  13.27800  1.000 42.09071  ?  241 VAL C HG13   1 
ATOM   3294 H  HG21   . VAL C 1 77 ? 5.44800   10.83500  14.11600  1.000 46.42089  ?  241 VAL C HG21   1 
ATOM   3295 H  HG22   . VAL C 1 77 ? 5.34800   11.18700  12.57000  1.000 46.42089  ?  241 VAL C HG22   1 
ATOM   3296 H  HG23   . VAL C 1 77 ? 6.29000   10.00300  13.05600  1.000 46.42089  ?  241 VAL C HG23   1 
ATOM   3297 N  N      . LYS C 1 78 ? 8.97000   14.13600  11.75600  1.000 38.28969  ?  242 LYS C N      1 
ATOM   3298 C  CA     . LYS C 1 78 ? 10.07300  15.06600  11.92400  1.000 40.88030  ?  242 LYS C CA     1 
ATOM   3299 C  C      . LYS C 1 78 ? 9.61500   16.32400  12.63100  1.000 39.69894  ?  242 LYS C C      1 
ATOM   3300 O  O      . LYS C 1 78 ? 8.48600   16.74000  12.47500  1.000 35.89036  ?  242 LYS C O      1 
ATOM   3301 C  CB     . LYS C 1 78 ? 10.68200  15.42000  10.58900  1.000 42.86482  ?  242 LYS C CB     1 
ATOM   3302 C  CG     . LYS C 1 78 ? 11.34400  14.16500  9.93400   1.000 52.79202  ?  242 LYS C CG     1 
ATOM   3303 C  CD     . LYS C 1 78 ? 12.31900  14.49200  8.79800   1.000 56.87659  ?  242 LYS C CD     1 
ATOM   3304 C  CE     . LYS C 1 78 ? 13.42900  13.40100  8.69900   1.000 60.39682  ?  242 LYS C CE     1 
ATOM   3305 N  NZ     . LYS C 1 78 ? 14.23100  13.26800  10.00000  1.000 60.58478  ?  242 LYS C NZ     1 
ATOM   3306 H  H      . LYS C 1 78 ? 8.30600   14.43800  11.30000  1.000 45.94763  ?  242 LYS C H      1 
ATOM   3307 H  HA     . LYS C 1 78 ? 10.76600  14.65900  12.46600  1.000 49.05636  ?  242 LYS C HA     1 
ATOM   3308 H  HB2    . LYS C 1 78 ? 9.98900   15.74600  9.99400   1.000 51.43778  ?  242 LYS C HB2    1 
ATOM   3309 H  HB3    . LYS C 1 78 ? 11.36500  16.09700  10.71600  1.000 51.43778  ?  242 LYS C HB3    1 
ATOM   3310 H  HG2    . LYS C 1 78 ? 11.83400  13.68100  10.61600  1.000 63.35042  ?  242 LYS C HG2    1 
ATOM   3311 H  HG3    . LYS C 1 78 ? 10.64500  13.60000  9.56900   1.000 63.35042  ?  242 LYS C HG3    1 
ATOM   3312 H  HD2    . LYS C 1 78 ? 11.83800  14.51800  7.95600   1.000 68.25191  ?  242 LYS C HD2    1 
ATOM   3313 H  HD3    . LYS C 1 78 ? 12.74300  15.34700  8.97200   1.000 68.25191  ?  242 LYS C HD3    1 
ATOM   3314 H  HE2    . LYS C 1 78 ? 13.01600  12.54400  8.51000   1.000 72.47619  ?  242 LYS C HE2    1 
ATOM   3315 H  HE3    . LYS C 1 78 ? 14.04500  13.63800  7.98800   1.000 72.47619  ?  242 LYS C HE3    1 
ATOM   3316 H  HZ1    . LYS C 1 78 ? 14.95400  12.76800  9.86100   1.000 72.70174  ?  242 LYS C HZ1    1 
ATOM   3317 H  HZ2    . LYS C 1 78 ? 14.48600  14.07200  10.28300  1.000 72.70174  ?  242 LYS C HZ2    1 
ATOM   3318 H  HZ3    . LYS C 1 78 ? 13.73200  12.88500  10.62900  1.000 72.70174  ?  242 LYS C HZ3    1 
ATOM   3319 N  N      . LYS C 1 79 ? 10.52500  16.91100  13.39200  1.000 36.22634  ?  243 LYS C N      1 
ATOM   3320 C  CA     . LYS C 1 79 ? 10.31500  18.16100  14.09100  1.000 42.16883  ?  243 LYS C CA     1 
ATOM   3321 C  C      . LYS C 1 79 ? 10.38700  19.31200  13.10900  1.000 42.87842  ?  243 LYS C C      1 
ATOM   3322 O  O      . LYS C 1 79 ? 11.25700  19.34800  12.26200  1.000 40.31620  ?  243 LYS C O      1 
ATOM   3323 C  CB     . LYS C 1 79 ? 11.38600  18.36300  15.19200  1.000 41.23774  ?  243 LYS C CB     1 
ATOM   3324 C  CG     . LYS C 1 79 ? 11.04000  19.50300  16.13300  1.000 40.96306  ?  243 LYS C CG     1 
ATOM   3325 C  CD     . LYS C 1 79 ? 9.90300   19.05700  17.05000  1.000 40.95928  ?  243 LYS C CD     1 
ATOM   3326 C  CE     . LYS C 1 79 ? 9.45300   20.14700  18.04200  1.000 48.15959  ?  243 LYS C CE     1 
ATOM   3327 N  NZ     . LYS C 1 79 ? 8.98100   21.37100  17.33600  1.000 45.04626  ?  243 LYS C NZ     1 
ATOM   3328 H  H      . LYS C 1 79 ? 11.31000  16.58400  13.52200  1.000 43.47161  ?  243 LYS C H      1 
ATOM   3329 H  HA     . LYS C 1 79 ? 9.43600   18.15700  14.49800  1.000 50.60260  ?  243 LYS C HA     1 
ATOM   3330 H  HB2    . LYS C 1 79 ? 11.45900  17.55000  15.71700  1.000 49.48529  ?  243 LYS C HB2    1 
ATOM   3331 H  HB3    . LYS C 1 79 ? 12.23700  18.56600  14.77300  1.000 49.48529  ?  243 LYS C HB3    1 
ATOM   3332 H  HG2    . LYS C 1 79 ? 11.81100  19.72300  16.67800  1.000 49.15567  ?  243 LYS C HG2    1 
ATOM   3333 H  HG3    . LYS C 1 79 ? 10.74700  20.27500  15.62500  1.000 49.15567  ?  243 LYS C HG3    1 
ATOM   3334 H  HD2    . LYS C 1 79 ? 9.13300   18.82000  16.51200  1.000 49.15114  ?  243 LYS C HD2    1 
ATOM   3335 H  HD3    . LYS C 1 79 ? 10.19600  18.28800  17.56400  1.000 49.15114  ?  243 LYS C HD3    1 
ATOM   3336 H  HE2    . LYS C 1 79 ? 8.72200   19.80700  18.58100  1.000 57.79150  ?  243 LYS C HE2    1 
ATOM   3337 H  HE3    . LYS C 1 79 ? 10.20100  20.39300  18.60800  1.000 57.79150  ?  243 LYS C HE3    1 
ATOM   3338 H  HZ1    . LYS C 1 79 ? 8.71700   21.98000  17.92800  1.000 54.05551  ?  243 LYS C HZ1    1 
ATOM   3339 H  HZ2    . LYS C 1 79 ? 9.64000   21.71200  16.84500  1.000 54.05551  ?  243 LYS C HZ2    1 
ATOM   3340 H  HZ3    . LYS C 1 79 ? 8.29700   21.17000  16.80300  1.000 54.05551  ?  243 LYS C HZ3    1 
ATOM   3341 N  N      . VAL C 1 80 ? 9.46200   20.23200  13.22000  1.000 40.52598  ?  244 VAL C N      1 
ATOM   3342 C  CA     . VAL C 1 80 ? 9.51500   21.47700  12.47600  1.000 43.54108  ?  244 VAL C CA     1 
ATOM   3343 C  C      . VAL C 1 80 ? 10.03100  22.56400  13.40300  1.000 53.75324  ?  244 VAL C C      1 
ATOM   3344 O  O      . VAL C 1 80 ? 9.80900   22.51800  14.63700  1.000 50.54444  ?  244 VAL C O      1 
ATOM   3345 C  CB     . VAL C 1 80 ? 8.10700   21.79700  11.93800  1.000 48.84183  ?  244 VAL C CB     1 
ATOM   3346 C  CG1    . VAL C 1 80 ? 8.03900   23.18600  11.25100  1.000 51.34856  ?  244 VAL C CG1    1 
ATOM   3347 C  CG2    . VAL C 1 80 ? 7.66800   20.66900  11.04400  1.000 45.63776  ?  244 VAL C CG2    1 
ATOM   3348 H  H      . VAL C 1 80 ? 8.77400   20.16300  13.73100  1.000 48.63118  ?  244 VAL C H      1 
ATOM   3349 H  HA     . VAL C 1 80 ? 10.12300  21.39100  11.72500  1.000 52.24930  ?  244 VAL C HA     1 
ATOM   3350 H  HB     . VAL C 1 80 ? 7.49500   21.82100  12.69000  1.000 58.61020  ?  244 VAL C HB     1 
ATOM   3351 H  HG11   . VAL C 1 80 ? 7.17400   23.28300  10.82400  1.000 61.61827  ?  244 VAL C HG11   1 
ATOM   3352 H  HG12   . VAL C 1 80 ? 8.15600   23.87700  11.92100  1.000 61.61827  ?  244 VAL C HG12   1 
ATOM   3353 H  HG13   . VAL C 1 80 ? 8.74400   23.24400  10.58700  1.000 61.61827  ?  244 VAL C HG13   1 
ATOM   3354 H  HG21   . VAL C 1 80 ? 6.85200   20.92800  10.58800  1.000 54.76532  ?  244 VAL C HG21   1 
ATOM   3355 H  HG22   . VAL C 1 80 ? 8.36700   20.49100  10.39500  1.000 54.76532  ?  244 VAL C HG22   1 
ATOM   3356 H  HG23   . VAL C 1 80 ? 7.50900   19.87900  11.58400  1.000 54.76532  ?  244 VAL C HG23   1 
ATOM   3357 N  N      . LYS C 1 81 ? 10.71000  23.56200  12.81500  1.000 51.52338  ?  245 LYS C N      1 
ATOM   3358 C  CA     . LYS C 1 81 ? 11.29400  24.67500  13.57000  1.000 57.99606  ?  245 LYS C CA     1 
ATOM   3359 C  C      . LYS C 1 81 ? 10.21500  25.72300  13.83100  1.000 59.22887  ?  245 LYS C C      1 
ATOM   3360 O  O      . LYS C 1 81 ? 10.33800  26.89600  13.47000  1.000 65.32424  ?  245 LYS C O      1 
ATOM   3361 C  CB     . LYS C 1 81 ? 12.47800  25.31000  12.84900  1.000 60.82699  ?  245 LYS C CB     1 
ATOM   3362 C  CG     . LYS C 1 81 ? 13.68900  24.42100  12.64800  1.000 63.33898  ?  245 LYS C CG     1 
ATOM   3363 C  CD     . LYS C 1 81 ? 14.45900  24.18800  13.92600  1.000 69.13144  ?  245 LYS C CD     1 
ATOM   3364 C  CE     . LYS C 1 81 ? 15.31300  25.39700  14.28900  1.000 78.76290  ?  245 LYS C CE     1 
ATOM   3365 N  NZ     . LYS C 1 81 ? 15.91900  25.27600  15.66600  1.000 81.70245  ?  245 LYS C NZ     1 
ATOM   3366 H  H      . LYS C 1 81 ? 10.84600  23.61400  11.96700  1.000 61.82806  ?  245 LYS C H      1 
ATOM   3367 H  HA     . LYS C 1 81 ? 11.60500  24.34600  14.42800  1.000 69.59527  ?  245 LYS C HA     1 
ATOM   3368 H  HB2    . LYS C 1 81 ? 12.18100  25.59400  11.97000  1.000 72.99238  ?  245 LYS C HB2    1 
ATOM   3369 H  HB3    . LYS C 1 81 ? 12.76300  26.08500  13.35700  1.000 72.99238  ?  245 LYS C HB3    1 
ATOM   3370 H  HG2    . LYS C 1 81 ? 13.39600  23.55900  12.31200  1.000 76.00677  ?  245 LYS C HG2    1 
ATOM   3371 H  HG3    . LYS C 1 81 ? 14.28700  24.84100  12.01000  1.000 76.00677  ?  245 LYS C HG3    1 
ATOM   3372 H  HD2    . LYS C 1 81 ? 13.83700  24.02600  14.65200  1.000 82.95773  ?  245 LYS C HD2    1 
ATOM   3373 H  HD3    . LYS C 1 81 ? 15.04600  23.42500  13.81100  1.000 82.95773  ?  245 LYS C HD3    1 
ATOM   3374 H  HE2    . LYS C 1 81 ? 16.03600  25.47800  13.64800  1.000 94.51548  ?  245 LYS C HE2    1 
ATOM   3375 H  HE3    . LYS C 1 81 ? 14.76300  26.19600  14.27300  1.000 94.51548  ?  245 LYS C HE3    1 
ATOM   3376 H  HZ1    . LYS C 1 81 ? 16.41000  25.99600  15.84600  1.000 98.04294  ?  245 LYS C HZ1    1 
ATOM   3377 H  HZ2    . LYS C 1 81 ? 15.27500  25.20500  16.27600  1.000 98.04294  ?  245 LYS C HZ2    1 
ATOM   3378 H  HZ3    . LYS C 1 81 ? 16.43800  24.55400  15.70700  1.000 98.04294  ?  245 LYS C HZ3    1 
ATOM   3379 N  N      . LYS C 1 82 ? 9.13900   25.24900  14.46200  1.000 57.69013  ?  246 LYS C N      1 
ATOM   3380 C  CA     . LYS C 1 82 ? 8.06800   26.08400  14.98000  1.000 56.78696  ?  246 LYS C CA     1 
ATOM   3381 C  C      . LYS C 1 82 ? 7.55600   25.39600  16.22900  1.000 53.58435  ?  246 LYS C C      1 
ATOM   3382 O  O      . LYS C 1 82 ? 7.60600   24.16500  16.34900  1.000 46.65859  ?  246 LYS C O      1 
ATOM   3383 C  CB     . LYS C 1 82 ? 6.92800   26.29800  13.97700  1.000 57.80805  ?  246 LYS C CB     1 
ATOM   3384 C  CG     . LYS C 1 82 ? 7.41200   26.74600  12.57900  1.000 79.92718  ?  246 LYS C CG     1 
ATOM   3385 C  CD     . LYS C 1 82 ? 8.08500   28.15700  12.58900  1.000 77.40489  ?  246 LYS C CD     1 
ATOM   3386 C  CE     . LYS C 1 82 ? 7.06500   29.27300  12.50700  1.000 81.16813  ?  246 LYS C CE     1 
ATOM   3387 N  NZ     . LYS C 1 82 ? 6.22300   29.13200  11.28100  1.000 87.32249  ?  246 LYS C NZ     1 
ATOM   3388 H  H      . LYS C 1 82 ? 9.00700   24.41400  14.61100  1.000 69.22815  ?  246 LYS C H      1 
ATOM   3389 H  HA     . LYS C 1 82 ? 8.42500   26.95000  15.23200  1.000 68.14436  ?  246 LYS C HA     1 
ATOM   3390 H  HB2    . LYS C 1 82 ? 6.44300   25.46500  13.87100  1.000 69.36966  ?  246 LYS C HB2    1 
ATOM   3391 H  HB3    . LYS C 1 82 ? 6.33400   26.98400  14.32000  1.000 69.36966  ?  246 LYS C HB3    1 
ATOM   3392 H  HG2    . LYS C 1 82 ? 8.06100   26.10700  12.24600  1.000 95.91262  ?  246 LYS C HG2    1 
ATOM   3393 H  HG3    . LYS C 1 82 ? 6.65000   26.78100  11.98000  1.000 95.91262  ?  246 LYS C HG3    1 
ATOM   3394 H  HD2    . LYS C 1 82 ? 8.56900   28.27900  13.41900  1.000 92.88587  ?  246 LYS C HD2    1 
ATOM   3395 H  HD3    . LYS C 1 82 ? 8.68600   28.23400  11.83200  1.000 92.88587  ?  246 LYS C HD3    1 
ATOM   3396 H  HE2    . LYS C 1 82 ? 6.48400   29.23700  13.28300  1.000 97.40175  ?  246 LYS C HE2    1 
ATOM   3397 H  HE3    . LYS C 1 82 ? 7.52400   30.12700  12.46700  1.000 97.40175  ?  246 LYS C HE3    1 
ATOM   3398 H  HZ1    . LYS C 1 82 ? 5.77800   29.88800  11.13000  1.000 104.78699 ?  246 LYS C HZ1    1 
ATOM   3399 H  HZ2    . LYS C 1 82 ? 6.73800   28.95400  10.57800  1.000 104.78699 ?  246 LYS C HZ2    1 
ATOM   3400 H  HZ3    . LYS C 1 82 ? 5.63900   28.46900  11.38600  1.000 104.78699 ?  246 LYS C HZ3    1 
ATOM   3401 N  N      . LYS C 1 83 ? 7.09100   26.20800  17.15700  1.000 52.19594  ?  247 LYS C N      1 
ATOM   3402 C  CA     . LYS C 1 83 ? 6.67600   25.71700  18.46300  1.000 53.25564  ?  247 LYS C CA     1 
ATOM   3403 C  C      . LYS C 1 83 ? 5.63700   24.60000  18.31600  1.000 44.49349  ?  247 LYS C C      1 
ATOM   3404 O  O      . LYS C 1 83 ? 4.60800   24.78100  17.65500  1.000 46.53824  ?  247 LYS C O      1 
ATOM   3405 C  CB     . LYS C 1 83 ? 6.13000   26.91000  19.25400  1.000 57.68041  ?  247 LYS C CB     1 
ATOM   3406 C  CG     . LYS C 1 83 ? 5.91900   26.68100  20.72400  1.000 57.17351  ?  247 LYS C CG     1 
ATOM   3407 C  CD     . LYS C 1 83 ? 5.38700   27.93800  21.39800  1.000 57.88814  ?  247 LYS C CD     1 
ATOM   3408 C  CE     . LYS C 1 83 ? 4.87900   27.60700  22.81500  0.335 59.64647  ?  247 LYS C CE     1 
ATOM   3409 N  NZ     . LYS C 1 83 ? 4.18700   28.71900  23.53700  1.000 73.70508  ?  247 LYS C NZ     1 
ATOM   3410 H  H      . LYS C 1 83 ? 7.00300   27.05800  17.05800  1.000 62.63513  ?  247 LYS C H      1 
ATOM   3411 H  HA     . LYS C 1 83 ? 7.44500   25.36100  18.93500  1.000 63.90677  ?  247 LYS C HA     1 
ATOM   3412 H  HB2    . LYS C 1 83 ? 6.75300   27.64800  19.16300  1.000 69.21649  ?  247 LYS C HB2    1 
ATOM   3413 H  HB3    . LYS C 1 83 ? 5.27400   27.16200  18.87400  1.000 69.21649  ?  247 LYS C HB3    1 
ATOM   3414 H  HG2    . LYS C 1 83 ? 5.27000   25.97200  20.84800  1.000 68.60821  ?  247 LYS C HG2    1 
ATOM   3415 H  HG3    . LYS C 1 83 ? 6.76300   26.44400  21.13900  1.000 68.60821  ?  247 LYS C HG3    1 
ATOM   3416 H  HD2    . LYS C 1 83 ? 6.09900   28.59300  21.47100  1.000 69.46576  ?  247 LYS C HD2    1 
ATOM   3417 H  HD3    . LYS C 1 83 ? 4.64800   28.29500  20.88100  1.000 69.46576  ?  247 LYS C HD3    1 
ATOM   3418 H  HE2    . LYS C 1 83 ? 4.26100   26.86200  22.75900  0.350 71.57577  ?  247 LYS C HE2    1 
ATOM   3419 H  HE3    . LYS C 1 83 ? 5.64400   27.35800  23.35100  0.333 71.57577  ?  247 LYS C HE3    1 
ATOM   3420 H  HZ1    . LYS C 1 83 ? 3.92800   28.44300  24.34300  1.000 88.44609  ?  247 LYS C HZ1    1 
ATOM   3421 H  HZ2    . LYS C 1 83 ? 4.74000   29.41000  23.63200  1.000 88.44609  ?  247 LYS C HZ2    1 
ATOM   3422 H  HZ3    . LYS C 1 83 ? 3.47200   28.98100  23.07700  1.000 88.44609  ?  247 LYS C HZ3    1 
ATOM   3423 N  N      . LEU C 1 84 ? 5.96500   23.42200  18.86300  1.000 42.77208  ?  248 LEU C N      1 
ATOM   3424 C  CA     . LEU C 1 84 ? 5.02700   22.30200  19.04200  1.000 43.38191  ?  248 LEU C CA     1 
ATOM   3425 C  C      . LEU C 1 84 ? 4.52500   21.73900  17.69800  1.000 38.29877  ?  248 LEU C C      1 
ATOM   3426 O  O      . LEU C 1 84 ? 3.46000   21.12900  17.63200  1.000 37.30472  ?  248 LEU C O      1 
ATOM   3427 C  CB     . LEU C 1 84 ? 3.82700   22.71200  19.90200  1.000 38.87144  ?  248 LEU C CB     1 
ATOM   3428 C  CG     . LEU C 1 84 ? 4.15200   23.19000  21.31600  1.000 44.60863  ?  248 LEU C CG     1 
ATOM   3429 C  CD1    . LEU C 1 84 ? 2.93500   23.82900  21.95700  1.000 42.94842  ?  248 LEU C CD1    1 
ATOM   3430 C  CD2    . LEU C 1 84 ? 4.63500   22.00400  22.09700  1.000 42.78925  ?  248 LEU C CD2    1 
ATOM   3431 H  H      . LEU C 1 84 ? 6.75600   23.24200  19.14900  1.000 51.32650  ?  248 LEU C H      1 
ATOM   3432 H  HA     . LEU C 1 84 ? 5.48900   21.58400  19.50200  1.000 52.05830  ?  248 LEU C HA     1 
ATOM   3433 H  HB2    . LEU C 1 84 ? 3.36200   23.43500  19.45200  1.000 46.64573  ?  248 LEU C HB2    1 
ATOM   3434 H  HB3    . LEU C 1 84 ? 3.23400   21.94900  19.98300  1.000 46.64573  ?  248 LEU C HB3    1 
ATOM   3435 H  HG     . LEU C 1 84 ? 4.86500   23.84500  21.28200  1.000 53.53035  ?  248 LEU C HG     1 
ATOM   3436 H  HD11   . LEU C 1 84 ? 3.16700   24.12100  22.85200  1.000 51.53810  ?  248 LEU C HD11   1 
ATOM   3437 H  HD12   . LEU C 1 84 ? 2.65900   24.59000  21.42200  1.000 51.53810  ?  248 LEU C HD12   1 
ATOM   3438 H  HD13   . LEU C 1 84 ? 2.22000   23.17500  21.99700  1.000 51.53810  ?  248 LEU C HD13   1 
ATOM   3439 H  HD21   . LEU C 1 84 ? 4.74400   22.26300  23.02600  1.000 51.34710  ?  248 LEU C HD21   1 
ATOM   3440 H  HD22   . LEU C 1 84 ? 3.98100   21.29100  22.02700  1.000 51.34710  ?  248 LEU C HD22   1 
ATOM   3441 H  HD23   . LEU C 1 84 ? 5.48500   21.71000  21.73500  1.000 51.34710  ?  248 LEU C HD23   1 
ATOM   3442 N  N      . THR C 1 85 ? 5.29500   21.90400  16.64800  1.000 35.22281  ?  249 THR C N      1 
ATOM   3443 C  CA     . THR C 1 85 ? 4.91400   21.49300  15.31000  1.000 39.16150  ?  249 THR C CA     1 
ATOM   3444 C  C      . THR C 1 85 ? 5.83300   20.38400  14.79300  1.000 36.22527  ?  249 THR C C      1 
ATOM   3445 O  O      . THR C 1 85 ? 7.04400   20.39300  15.03400  1.000 33.22642  ?  249 THR C O      1 
ATOM   3446 C  CB     . THR C 1 85 ? 4.94100   22.70400  14.35500  1.000 40.66733  ?  249 THR C CB     1 
ATOM   3447 O  OG1    . THR C 1 85 ? 4.08900   23.74800  14.85800  1.000 43.53425  ?  249 THR C OG1    1 
ATOM   3448 C  CG2    . THR C 1 85 ? 4.47700   22.30600  12.96800  1.000 39.71698  ?  249 THR C CG2    1 
ATOM   3449 H  H      . THR C 1 85 ? 6.07500   22.26500  16.68200  1.000 42.26737  ?  249 THR C H      1 
ATOM   3450 H  HA     . THR C 1 85 ? 4.00800   21.14700  15.32600  1.000 46.99380  ?  249 THR C HA     1 
ATOM   3451 H  HB     . THR C 1 85 ? 5.84900   23.03800  14.28700  1.000 48.80080  ?  249 THR C HB     1 
ATOM   3452 H  HG1    . THR C 1 85 ? 4.35700   23.99900  15.61400  1.000 52.24110  ?  249 THR C HG1    1 
ATOM   3453 H  HG21   . THR C 1 85 ? 4.34600   23.09800  12.42400  1.000 47.66037  ?  249 THR C HG21   1 
ATOM   3454 H  HG22   . THR C 1 85 ? 5.14000   21.74000  12.54300  1.000 47.66037  ?  249 THR C HG22   1 
ATOM   3455 H  HG23   . THR C 1 85 ? 3.63800   21.82300  13.02500  1.000 47.66037  ?  249 THR C HG23   1 
ATOM   3456 N  N      . TYR C 1 86 ? 5.23200   19.41300  14.09700  1.000 33.71730  ?  250 TYR C N      1 
ATOM   3457 C  CA     . TYR C 1 86 ? 5.87800   18.20500  13.65400  1.000 32.12301  ?  250 TYR C CA     1 
ATOM   3458 C  C      . TYR C 1 86 ? 5.34500   17.92400  12.25000  1.000 36.40858  ?  250 TYR C C      1 
ATOM   3459 O  O      . TYR C 1 86 ? 4.40200   18.57100  11.79800  1.000 37.03010  ?  250 TYR C O      1 
ATOM   3460 C  CB     . TYR C 1 86 ? 5.59600   17.01500  14.55900  1.000 32.91333  ?  250 TYR C CB     1 
ATOM   3461 C  CG     . TYR C 1 86 ? 6.14300   17.13900  15.96100  1.000 39.76769  ?  250 TYR C CG     1 
ATOM   3462 C  CD1    . TYR C 1 86 ? 5.46300   17.86600  16.94300  1.000 37.58547  ?  250 TYR C CD1    1 
ATOM   3463 C  CD2    . TYR C 1 86 ? 7.33000   16.50200  16.31400  1.000 35.76814  ?  250 TYR C CD2    1 
ATOM   3464 C  CE1    . TYR C 1 86 ? 5.97900   17.95400  18.25000  1.000 40.12031  ?  250 TYR C CE1    1 
ATOM   3465 C  CE2    . TYR C 1 86 ? 7.82800   16.58700  17.55800  1.000 39.52291  ?  250 TYR C CE2    1 
ATOM   3466 C  CZ     . TYR C 1 86 ? 7.16000   17.31300  18.53000  1.000 38.11509  ?  250 TYR C CZ     1 
ATOM   3467 O  OH     . TYR C 1 86 ? 7.69900   17.36600  19.77400  1.000 46.40834  ?  250 TYR C OH     1 
ATOM   3468 H  H      . TYR C 1 86 ? 4.40500   19.44900  13.86500  1.000 40.46076  ?  250 TYR C H      1 
ATOM   3469 H  HA     . TYR C 1 86 ? 6.83700   18.34200  13.60400  1.000 38.54761  ?  250 TYR C HA     1 
ATOM   3470 H  HB2    . TYR C 1 86 ? 4.63500   16.90300  14.62900  1.000 39.49600  ?  250 TYR C HB2    1 
ATOM   3471 H  HB3    . TYR C 1 86 ? 5.98800   16.22200  14.16000  1.000 39.49600  ?  250 TYR C HB3    1 
ATOM   3472 H  HD1    . TYR C 1 86 ? 4.66500   18.29400  16.73200  1.000 45.10256  ?  250 TYR C HD1    1 
ATOM   3473 H  HD2    . TYR C 1 86 ? 7.79100   16.01200  15.67200  1.000 42.92177  ?  250 TYR C HD2    1 
ATOM   3474 H  HE1    . TYR C 1 86 ? 5.53400   18.44100  18.90600  1.000 48.14437  ?  250 TYR C HE1    1 
ATOM   3475 H  HE2    . TYR C 1 86 ? 8.62500   16.15600  17.76800  1.000 47.42749  ?  250 TYR C HE2    1 
ATOM   3476 H  HH     . TYR C 1 86 ? 8.41700   16.93000  19.79500  1.000 55.69001  ?  250 TYR C HH     1 
ATOM   3477 N  N      . GLN C 1 87 ? 5.87800   16.90000  11.59600  1.000 33.78371  ?  251 GLN C N      1 
ATOM   3478 C  CA     . GLN C 1 87 ? 5.50800   16.62200  10.21200  1.000 33.15716  ?  251 GLN C CA     1 
ATOM   3479 C  C      . GLN C 1 87 ? 5.61600   15.13500  9.96900   1.000 30.47579  ?  251 GLN C C      1 
ATOM   3480 O  O      . GLN C 1 87 ? 6.69700   14.58000  10.03900  1.000 34.36630  ?  251 GLN C O      1 
ATOM   3481 C  CB     . GLN C 1 87 ? 6.42000   17.38300  9.20500   1.000 37.03499  ?  251 GLN C CB     1 
ATOM   3482 C  CG     . GLN C 1 87 ? 6.03200   17.18100  7.69400   1.000 41.50237  ?  251 GLN C CG     1 
ATOM   3483 C  CD     . GLN C 1 87 ? 6.96200   17.90800  6.66900   1.000 46.44659  ?  251 GLN C CD     1 
ATOM   3484 O  OE1    . GLN C 1 87 ? 7.83000   18.71200  7.01100   1.000 52.42024  ?  251 GLN C OE1    1 
ATOM   3485 N  NE2    . GLN C 1 87 ? 6.75900   17.59400  5.40200   1.000 51.14071  ?  251 GLN C NE2    1 
ATOM   3486 H  H      . GLN C 1 87 ? 6.45300   16.35300  11.92700  1.000 40.54046  ?  251 GLN C H      1 
ATOM   3487 H  HA     . GLN C 1 87 ? 4.58900   16.89200  10.06000  1.000 39.78859  ?  251 GLN C HA     1 
ATOM   3488 H  HB2    . GLN C 1 87 ? 6.37000   18.33200  9.39700   1.000 44.44199  ?  251 GLN C HB2    1 
ATOM   3489 H  HB3    . GLN C 1 87 ? 7.33300   17.07400  9.31800   1.000 44.44199  ?  251 GLN C HB3    1 
ATOM   3490 H  HG2    . GLN C 1 87 ? 6.06500   16.23500  7.49200   1.000 49.80285  ?  251 GLN C HG2    1 
ATOM   3491 H  HG3    . GLN C 1 87 ? 5.13000   17.51200  7.55900   1.000 49.80285  ?  251 GLN C HG3    1 
ATOM   3492 H  HE21   . GLN C 1 87 ? 6.14600   17.02800  5.19200   1.000 61.36885  ?  251 GLN C HE21   1 
ATOM   3493 H  HE22   . GLN C 1 87 ? 7.23700   17.95800  4.78700   1.000 61.36885  ?  251 GLN C HE22   1 
ATOM   3494 N  N      . PHE C 1 88 ? 4.51600   14.50400  9.61500   1.000 31.52033  ?  252 PHE C N      1 
ATOM   3495 C  CA     . PHE C 1 88 ? 4.58700   13.11700  9.17100   1.000 34.28678  ?  252 PHE C CA     1 
ATOM   3496 C  C      . PHE C 1 88 ? 5.40500   13.02700  7.88300   1.000 36.37821  ?  252 PHE C C      1 
ATOM   3497 O  O      . PHE C 1 88 ? 5.51600   13.99500  7.13400   1.000 35.67781  ?  252 PHE C O      1 
ATOM   3498 C  CB     . PHE C 1 88 ? 3.16900   12.55900  8.94300   1.000 38.33035  ?  252 PHE C CB     1 
ATOM   3499 C  CG     . PHE C 1 88 ? 2.32900   12.46700  10.20600  1.000 36.14915  ?  252 PHE C CG     1 
ATOM   3500 C  CD1    . PHE C 1 88 ? 2.65300   11.54300  11.19300  1.000 37.13942  ?  252 PHE C CD1    1 
ATOM   3501 C  CD2    . PHE C 1 88 ? 1.22700   13.29100  10.38300  1.000 37.67528  ?  252 PHE C CD2    1 
ATOM   3502 C  CE1    . PHE C 1 88 ? 1.90400   11.44500  12.37500  1.000 38.41108  ?  252 PHE C CE1    1 
ATOM   3503 C  CE2    . PHE C 1 88 ? 0.43100   13.20400  11.57600  1.000 39.27067  ?  252 PHE C CE2    1 
ATOM   3504 C  CZ     . PHE C 1 88 ? 0.79800   12.27200  12.56600  1.000 32.23367  ?  252 PHE C CZ     1 
ATOM   3505 H  H      . PHE C 1 88 ? 3.72600   14.84300  9.62000   1.000 37.82439  ?  252 PHE C H      1 
ATOM   3506 H  HA     . PHE C 1 88 ? 5.02300   12.58100  9.85100   1.000 41.14414  ?  252 PHE C HA     1 
ATOM   3507 H  HB2    . PHE C 1 88 ? 2.70300   13.13800  8.31900   1.000 45.99643  ?  252 PHE C HB2    1 
ATOM   3508 H  HB3    . PHE C 1 88 ? 3.24200   11.66600  8.57100   1.000 45.99643  ?  252 PHE C HB3    1 
ATOM   3509 H  HD1    . PHE C 1 88 ? 3.39500   10.99400  11.07700  1.000 44.56731  ?  252 PHE C HD1    1 
ATOM   3510 H  HD2    . PHE C 1 88 ? 1.00200   13.90700  9.72400   1.000 45.21033  ?  252 PHE C HD2    1 
ATOM   3511 H  HE1    . PHE C 1 88 ? 2.13900   10.82300  13.02500  1.000 46.09330  ?  252 PHE C HE1    1 
ATOM   3512 H  HE2    . PHE C 1 88 ? -0.30400  13.76100  11.69800  1.000 47.12480  ?  252 PHE C HE2    1 
ATOM   3513 H  HZ     . PHE C 1 88 ? 0.29400   12.19900  13.34400  1.000 38.68040  ?  252 PHE C HZ     1 
ATOM   3514 N  N      . SER C 1 89 ? 6.00500   11.86400  7.65800   1.000 33.36001  ?  253 SER C N      1 
ATOM   3515 C  CA     . SER C 1 89 ? 6.62400   11.51600  6.38900   1.000 43.03322  ?  253 SER C CA     1 
ATOM   3516 C  C      . SER C 1 89 ? 5.56800   11.04700  5.36700   1.000 48.51682  ?  253 SER C C      1 
ATOM   3517 O  O      . SER C 1 89 ? 4.48100   10.55500  5.72900   1.000 48.85338  ?  253 SER C O      1 
ATOM   3518 C  CB     . SER C 1 89 ? 7.63800   10.40400  6.59900   1.000 38.86809  ?  253 SER C CB     1 
ATOM   3519 O  OG     . SER C 1 89 ? 6.98800   9.13100   6.73200   1.000 43.69305  ?  253 SER C OG     1 
ATOM   3520 H  H      . SER C 1 89 ? 6.06700   11.24100  8.24700   1.000 40.03201  ?  253 SER C H      1 
ATOM   3521 H  HA     . SER C 1 89 ? 7.08300   12.29000  6.02700   1.000 51.63986  ?  253 SER C HA     1 
ATOM   3522 H  HB2    . SER C 1 89 ? 8.23700   10.37500  5.83600   1.000 46.64171  ?  253 SER C HB2    1 
ATOM   3523 H  HB3    . SER C 1 89 ? 8.14000   10.58700  7.40800   1.000 46.64171  ?  253 SER C HB3    1 
ATOM   3524 H  HG     . SER C 1 89 ? 7.55500   8.51500   6.69100   1.000 52.43166  ?  253 SER C HG     1 
ATOM   3525 N  N      . GLY C 1 90 ? 5.91100   11.19200  4.07900   1.000 55.33216  ?  254 GLY C N      1 
ATOM   3526 C  CA     . GLY C 1 90 ? 5.02700   10.70100  3.00700   1.000 55.47806  ?  254 GLY C CA     1 
ATOM   3527 C  C      . GLY C 1 90 ? 4.64700   9.24000   3.17300   1.000 56.72966  ?  254 GLY C C      1 
ATOM   3528 O  O      . GLY C 1 90 ? 3.48400   8.87700   3.01300   1.000 60.25337  ?  254 GLY C O      1 
ATOM   3529 H  H      . GLY C 1 90 ? 6.63600   11.56400  3.80200   1.000 66.39860  ?  254 GLY C H      1 
ATOM   3530 H  HA2    . GLY C 1 90 ? 4.21300   11.22900  2.99500   1.000 66.57368  ?  254 GLY C HA2    1 
ATOM   3531 H  HA3    . GLY C 1 90 ? 5.47200   10.80500  2.15100   1.000 66.57368  ?  254 GLY C HA3    1 
ATOM   3532 N  N      . GLU C 1 91 ? 5.61000   8.39100   3.54700   1.000 59.60163  ?  255 GLU C N      1 
ATOM   3533 C  CA     . GLU C 1 91 ? 5.32300   6.97000   3.73300   1.000 66.45787  ?  255 GLU C CA     1 
ATOM   3534 C  C      . GLU C 1 91 ? 4.20000   6.75300   4.75800   1.000 69.05256  ?  255 GLU C C      1 
ATOM   3535 O  O      . GLU C 1 91 ? 3.23000   6.02800   4.49700   1.000 70.30091  ?  255 GLU C O      1 
ATOM   3536 C  CB     . GLU C 1 91 ? 6.62300   6.27100   4.13400   1.000 71.62138  ?  255 GLU C CB     1 
ATOM   3537 C  CG     . GLU C 1 91 ? 6.56300   4.75700   4.28400   1.000 81.23889  ?  255 GLU C CG     1 
ATOM   3538 C  CD     . GLU C 1 91 ? 7.37300   4.26700   5.50800   1.000 94.74834  ?  255 GLU C CD     1 
ATOM   3539 O  OE1    . GLU C 1 91 ? 6.94500   4.52100   6.67300   1.000 94.78132  ?  255 GLU C OE1    1 
ATOM   3540 O  OE2    . GLU C 1 91 ? 8.44700   3.64200   5.29800   1.000 93.22584  -1 255 GLU C OE2    1 
ATOM   3541 H  H      . GLU C 1 91 ? 6.42700   8.61200   3.69700   1.000 71.52196  ?  255 GLU C H      1 
ATOM   3542 H  HA     . GLU C 1 91 ? 5.03100   6.59500   2.88800   1.000 79.74944  ?  255 GLU C HA     1 
ATOM   3543 H  HB2    . GLU C 1 91 ? 7.29300   6.46600   3.46000   1.000 85.94566  ?  255 GLU C HB2    1 
ATOM   3544 H  HB3    . GLU C 1 91 ? 6.91100   6.63300   4.98700   1.000 85.94566  ?  255 GLU C HB3    1 
ATOM   3545 H  HG2    . GLU C 1 91 ? 5.64100   4.48100   4.40100   1.000 97.48667  ?  255 GLU C HG2    1 
ATOM   3546 H  HG3    . GLU C 1 91 ? 6.93700   4.34400   3.49000   1.000 97.48667  ?  255 GLU C HG3    1 
ATOM   3547 N  N      . VAL C 1 92 ? 4.29100   7.41600   5.91800   1.000 67.45667  ?  256 VAL C N      1 
ATOM   3548 C  CA     . VAL C 1 92 ? 3.32800   7.22100   7.00100   1.000 63.04318  ?  256 VAL C CA     1 
ATOM   3549 C  C      . VAL C 1 92 ? 1.92400   7.60800   6.55800   1.000 65.46037  ?  256 VAL C C      1 
ATOM   3550 O  O      . VAL C 1 92 ? 0.92900   6.96400   6.93700   1.000 67.81587  ?  256 VAL C O      1 
ATOM   3551 C  CB     . VAL C 1 92 ? 3.77700   8.03700   8.23000   1.000 55.68295  ?  256 VAL C CB     1 
ATOM   3552 C  CG1    . VAL C 1 92 ? 2.62300   8.28000   9.20800   1.000 62.39801  ?  256 VAL C CG1    1 
ATOM   3553 C  CG2    . VAL C 1 92 ? 4.94500   7.34500   8.91100   1.000 56.33080  ?  256 VAL C CG2    1 
ATOM   3554 H  H      . VAL C 1 92 ? 4.90700   7.98800   6.10000   1.000 80.94800  ?  256 VAL C H      1 
ATOM   3555 H  HA     . VAL C 1 92 ? 3.31700   6.28400   7.25000   1.000 75.65181  ?  256 VAL C HA     1 
ATOM   3556 H  HB     . VAL C 1 92 ? 4.08900   8.90400   7.92600   1.000 66.81954  ?  256 VAL C HB     1 
ATOM   3557 H  HG11   . VAL C 1 92 ? 2.99000   8.55400   10.06300  1.000 74.87761  ?  256 VAL C HG11   1 
ATOM   3558 H  HG12   . VAL C 1 92 ? 2.04900   8.98000   8.85800   1.000 74.87761  ?  256 VAL C HG12   1 
ATOM   3559 H  HG13   . VAL C 1 92 ? 2.12000   7.45700   9.31500   1.000 74.87761  ?  256 VAL C HG13   1 
ATOM   3560 H  HG21   . VAL C 1 92 ? 5.56300   8.02400   9.22000   1.000 67.59696  ?  256 VAL C HG21   1 
ATOM   3561 H  HG22   . VAL C 1 92 ? 4.61500   6.82500   9.66100   1.000 67.59696  ?  256 VAL C HG22   1 
ATOM   3562 H  HG23   . VAL C 1 92 ? 5.38700   6.76700   8.27000   1.000 67.59696  ?  256 VAL C HG23   1 
ATOM   3563 N  N      . LEU C 1 93 ? 1.81800   8.67700   5.78000   1.000 61.13205  ?  257 LEU C N      1 
ATOM   3564 C  CA     . LEU C 1 93 ? 0.54300   9.12300   5.22600   1.000 66.42346  ?  257 LEU C CA     1 
ATOM   3565 C  C      . LEU C 1 93 ? -0.07400  8.16000   4.18700   1.000 73.05376  ?  257 LEU C C      1 
ATOM   3566 O  O      . LEU C 1 93 ? -1.16600  8.46200   3.69200   1.000 72.17869  ?  257 LEU C O      1 
ATOM   3567 C  CB     . LEU C 1 93 ? 0.75000   10.50300  4.61700   1.000 56.77308  ?  257 LEU C CB     1 
ATOM   3568 C  CG     . LEU C 1 93 ? 1.15500   11.56600  5.62600   1.000 58.42889  ?  257 LEU C CG     1 
ATOM   3569 C  CD1    . LEU C 1 93 ? 1.73200   12.79900  4.93900   1.000 47.51344  ?  257 LEU C CD1    1 
ATOM   3570 C  CD2    . LEU C 1 93 ? -0.06100  11.96900  6.48200   1.000 48.20910  ?  257 LEU C CD2    1 
ATOM   3571 H  H      . LEU C 1 93 ? 2.48300   9.17200   5.55300   1.000 73.35845  ?  257 LEU C H      1 
ATOM   3572 H  HA     . LEU C 1 93 ? -0.09400  9.21300   5.95200   1.000 79.70816  ?  257 LEU C HA     1 
ATOM   3573 H  HB2    . LEU C 1 93 ? 1.45000   10.44700  3.94800   1.000 68.12770  ?  257 LEU C HB2    1 
ATOM   3574 H  HB3    . LEU C 1 93 ? -0.07900  10.78900  4.20200   1.000 68.12770  ?  257 LEU C HB3    1 
ATOM   3575 H  HG     . LEU C 1 93 ? 1.83400   11.20600  6.21700   1.000 70.11467  ?  257 LEU C HG     1 
ATOM   3576 H  HD11   . LEU C 1 93 ? 1.97600   13.45100  5.61400   1.000 57.01613  ?  257 LEU C HD11   1 
ATOM   3577 H  HD12   . LEU C 1 93 ? 2.51700   12.53900  4.43100   1.000 57.01613  ?  257 LEU C HD12   1 
ATOM   3578 H  HD13   . LEU C 1 93 ? 1.06200   13.17200  4.34500   1.000 57.01613  ?  257 LEU C HD13   1 
ATOM   3579 H  HD21   . LEU C 1 93 ? 0.19500   12.69700  7.07000   1.000 57.85092  ?  257 LEU C HD21   1 
ATOM   3580 H  HD22   . LEU C 1 93 ? -0.77900  12.25500  5.89500   1.000 57.85092  ?  257 LEU C HD22   1 
ATOM   3581 H  HD23   . LEU C 1 93 ? -0.34700  11.20500  7.00600   1.000 57.85092  ?  257 LEU C HD23   1 
ATOM   3582 N  N      . GLY C 1 94 ? 0.56400   7.02900   3.84900   1.000 79.26240  ?  258 GLY C N      1 
ATOM   3583 C  CA     . GLY C 1 94 ? -0.07200  5.97400   3.05800   1.000 81.87402  ?  258 GLY C CA     1 
ATOM   3584 C  C      . GLY C 1 94 ? -0.41300  4.70800   3.84600   1.000 85.76757  ?  258 GLY C C      1 
ATOM   3585 O  O      . GLY C 1 94 ? -1.14700  3.83900   3.35900   1.000 83.03352  ?  258 GLY C O      1 
ATOM   3586 H  H      . GLY C 1 94 ? 1.37600   6.85100   4.07100   1.000 95.11488  ?  258 GLY C H      1 
ATOM   3587 H  HA2    . GLY C 1 94 ? -0.89300  6.31500   2.67000   1.000 98.24882  ?  258 GLY C HA2    1 
ATOM   3588 H  HA3    . GLY C 1 94 ? 0.52100   5.72400   2.33300   1.000 98.24882  ?  258 GLY C HA3    1 
ATOM   3589 N  N      . ARG C 1 95 ? 0.14100   4.59400   5.05900   1.000 92.80630  ?  259 ARG C N      1 
ATOM   3590 C  CA     . ARG C 1 95 ? -0.12100  3.49100   6.00100   1.000 89.04212  ?  259 ARG C CA     1 
ATOM   3591 C  C      . ARG C 1 95 ? -0.05400  4.01600   7.45200   1.000 84.27428  ?  259 ARG C C      1 
ATOM   3592 O  O      . ARG C 1 95 ? -1.04500  4.01000   8.19900   1.000 83.14391  ?  259 ARG C O      1 
ATOM   3593 C  CB     . ARG C 1 95 ? 0.89200   2.35700   5.80900   1.000 86.34178  ?  259 ARG C CB     1 
ATOM   3594 H  H      . ARG C 1 95 ? 0.69800   5.16900   5.37400   1.000 111.36756 ?  259 ARG C H      1 
ATOM   3595 H  HA     . ARG C 1 95 ? -1.01000  3.13700   5.84400   1.000 106.85054 ?  259 ARG C HA     1 
ATOM   3596 O  "O5'"  . DA  D 2 1  ? 18.49500  36.30900  34.06800  1.000 97.40691  ?  1   DA  D "O5'"  1 
ATOM   3597 C  "C5'"  . DA  D 2 1  ? 17.22800  35.83600  34.55300  1.000 98.44979  ?  1   DA  D "C5'"  1 
ATOM   3598 C  "C4'"  . DA  D 2 1  ? 16.44300  36.95700  35.22100  1.000 97.88168  ?  1   DA  D "C4'"  1 
ATOM   3599 O  "O4'"  . DA  D 2 1  ? 16.40300  38.11300  34.35200  1.000 89.97288  ?  1   DA  D "O4'"  1 
ATOM   3600 C  "C3'"  . DA  D 2 1  ? 14.98500  36.63200  35.52500  1.000 99.87069  ?  1   DA  D "C3'"  1 
ATOM   3601 O  "O3'"  . DA  D 2 1  ? 14.58900  37.23500  36.75700  1.000 107.50989 ?  1   DA  D "O3'"  1 
ATOM   3602 C  "C2'"  . DA  D 2 1  ? 14.20500  37.18900  34.32300  1.000 96.71636  ?  1   DA  D "C2'"  1 
ATOM   3603 C  "C1'"  . DA  D 2 1  ? 15.19400  38.11300  33.61000  1.000 89.36436  ?  1   DA  D "C1'"  1 
ATOM   3604 N  N9     . DA  D 2 1  ? 15.49400  37.74000  32.20500  1.000 85.75092  ?  1   DA  D N9     1 
ATOM   3605 C  C8     . DA  D 2 1  ? 16.72600  37.48600  31.66100  1.000 82.95269  ?  1   DA  D C8     1 
ATOM   3606 N  N7     . DA  D 2 1  ? 16.69600  37.22000  30.38000  1.000 80.71832  ?  1   DA  D N7     1 
ATOM   3607 C  C5     . DA  D 2 1  ? 15.36000  37.31300  30.05400  1.000 78.38030  ?  1   DA  D C5     1 
ATOM   3608 C  C6     . DA  D 2 1  ? 14.67400  37.14400  28.84300  1.000 79.78835  ?  1   DA  D C6     1 
ATOM   3609 N  N6     . DA  D 2 1  ? 15.28200  36.83600  27.69300  1.000 80.51790  ?  1   DA  D N6     1 
ATOM   3610 N  N1     . DA  D 2 1  ? 13.33600  37.30700  28.85500  1.000 78.58730  ?  1   DA  D N1     1 
ATOM   3611 C  C2     . DA  D 2 1  ? 12.73400  37.61800  30.00200  1.000 77.84597  ?  1   DA  D C2     1 
ATOM   3612 N  N3     . DA  D 2 1  ? 13.27200  37.80300  31.20000  1.000 81.70305  ?  1   DA  D N3     1 
ATOM   3613 C  C4     . DA  D 2 1  ? 14.60200  37.63400  31.15800  1.000 78.70089  ?  1   DA  D C4     1 
ATOM   3614 H  "H5'"  . DA  D 2 1  ? 17.37900  35.12600  35.19700  1.000 118.13975 ?  1   DA  D "H5'"  1 
ATOM   3615 H  "H5''" . DA  D 2 1  ? 16.71300  35.48700  33.80900  1.000 118.13975 ?  1   DA  D "H5''" 1 
ATOM   3616 H  "H4'"  . DA  D 2 1  ? 16.88800  37.20200  36.04700  1.000 117.45801 ?  1   DA  D "H4'"  1 
ATOM   3617 H  "H3'"  . DA  D 2 1  ? 14.86700  35.67100  35.57600  1.000 119.84483 ?  1   DA  D "H3'"  1 
ATOM   3618 H  "H2'"  . DA  D 2 1  ? 13.93000  36.47100  33.73500  1.000 116.05964 ?  1   DA  D "H2'"  1 
ATOM   3619 H  "H2''" . DA  D 2 1  ? 13.43300  37.69200  34.62600  1.000 116.05964 ?  1   DA  D "H2''" 1 
ATOM   3620 H  "H1'"  . DA  D 2 1  ? 14.83100  39.01200  33.61600  1.000 107.23724 ?  1   DA  D "H1'"  1 
ATOM   3621 H  H8     . DA  D 2 1  ? 17.51200  37.50100  32.15700  1.000 99.54323  ?  1   DA  D H8     1 
ATOM   3622 H  H61    . DA  D 2 1  ? 14.82000  36.74400  26.97300  1.000 96.62148  ?  1   DA  D H61    1 
ATOM   3623 H  H62    . DA  D 2 1  ? 16.13500  36.73000  27.67300  1.000 96.62148  ?  1   DA  D H62    1 
ATOM   3624 H  H2     . DA  D 2 1  ? 11.81100  37.72200  29.95600  1.000 93.41516  ?  1   DA  D H2     1 
ATOM   3625 H  "HO5'" . DA  D 2 1  ? 19.02000  35.78100  33.68000  1.000 116.88829 ?  1   DA  D "HO5'" 1 
ATOM   3626 P  P      . DA  D 2 2  ? 13.10800  37.08600  37.37100  1.000 128.07236 ?  2   DA  D P      1 
ATOM   3627 O  OP1    . DA  D 2 2  ? 12.26800  38.31100  37.06500  1.000 125.38956 -1 2   DA  D OP1    1 
ATOM   3628 O  OP2    . DA  D 2 2  ? 13.15100  36.73400  38.84400  1.000 121.68969 ?  2   DA  D OP2    1 
ATOM   3629 O  "O5'"  . DA  D 2 2  ? 12.45400  35.81600  36.61400  1.000 119.18708 ?  2   DA  D "O5'"  1 
ATOM   3630 C  "C5'"  . DA  D 2 2  ? 11.04000  35.80400  36.29100  1.000 106.01475 ?  2   DA  D "C5'"  1 
ATOM   3631 C  "C4'"  . DA  D 2 2  ? 10.79400  34.72900  35.26400  1.000 99.66858  ?  2   DA  D "C4'"  1 
ATOM   3632 O  "O4'"  . DA  D 2 2  ? 11.64900  34.96100  34.13800  1.000 95.06016  ?  2   DA  D "O4'"  1 
ATOM   3633 C  "C3'"  . DA  D 2 2  ? 11.13100  33.30600  35.71400  1.000 96.26381  ?  2   DA  D "C3'"  1 
ATOM   3634 O  "O3'"  . DA  D 2 2  ? 10.07200  32.63900  36.42000  1.000 97.03520  ?  2   DA  D "O3'"  1 
ATOM   3635 C  "C2'"  . DA  D 2 2  ? 11.51800  32.61500  34.39900  1.000 88.38225  ?  2   DA  D "C2'"  1 
ATOM   3636 C  "C1'"  . DA  D 2 2  ? 11.67500  33.75100  33.39400  1.000 88.57773  ?  2   DA  D "C1'"  1 
ATOM   3637 N  N9     . DA  D 2 2  ? 12.92300  33.75300  32.63700  1.000 82.22135  ?  2   DA  D N9     1 
ATOM   3638 C  C8     . DA  D 2 2  ? 14.20500  33.92300  33.09600  1.000 85.41929  ?  2   DA  D C8     1 
ATOM   3639 N  N7     . DA  D 2 2  ? 15.10300  33.90900  32.14500  1.000 80.78166  ?  2   DA  D N7     1 
ATOM   3640 C  C5     . DA  D 2 2  ? 14.36900  33.73200  30.98200  1.000 75.37788  ?  2   DA  D C5     1 
ATOM   3641 C  C6     . DA  D 2 2  ? 14.74500  33.63200  29.63000  1.000 76.71538  ?  2   DA  D C6     1 
ATOM   3642 N  N6     . DA  D 2 2  ? 16.00300  33.69800  29.20700  1.000 79.69131  ?  2   DA  D N6     1 
ATOM   3643 N  N1     . DA  D 2 2  ? 13.76100  33.45400  28.72000  1.000 73.87458  ?  2   DA  D N1     1 
ATOM   3644 C  C2     . DA  D 2 2  ? 12.49600  33.39300  29.15300  1.000 76.75198  ?  2   DA  D C2     1 
ATOM   3645 N  N3     . DA  D 2 2  ? 12.02400  33.47100  30.39100  1.000 77.06921  ?  2   DA  D N3     1 
ATOM   3646 C  C4     . DA  D 2 2  ? 13.02200  33.64500  31.27000  1.000 76.50485  ?  2   DA  D C4     1 
ATOM   3647 H  "H5'"  . DA  D 2 2  ? 10.78000  36.66600  35.93000  1.000 127.21770 ?  2   DA  D "H5'"  1 
ATOM   3648 H  "H5''" . DA  D 2 2  ? 10.52400  35.61600  37.09100  1.000 127.21770 ?  2   DA  D "H5''" 1 
ATOM   3649 H  "H4'"  . DA  D 2 2  ? 9.87100   34.76700  34.97500  1.000 119.60230 ?  2   DA  D "H4'"  1 
ATOM   3650 H  "H3'"  . DA  D 2 2  ? 11.91200  33.33900  36.28800  1.000 115.51657 ?  2   DA  D "H3'"  1 
ATOM   3651 H  "H2'"  . DA  D 2 2  ? 12.35600  32.13700  34.50200  1.000 106.05870 ?  2   DA  D "H2'"  1 
ATOM   3652 H  "H2''" . DA  D 2 2  ? 10.81600  32.01000  34.11600  1.000 106.05870 ?  2   DA  D "H2''" 1 
ATOM   3653 H  "H1'"  . DA  D 2 2  ? 10.92600  33.73900  32.77700  1.000 106.29328 ?  2   DA  D "H1'"  1 
ATOM   3654 H  H8     . DA  D 2 2  ? 14.41500  34.03000  33.99600  1.000 102.50315 ?  2   DA  D H8     1 
ATOM   3655 H  H61    . DA  D 2 2  ? 16.17900  33.62800  28.36800  1.000 95.62957  ?  2   DA  D H61    1 
ATOM   3656 H  H62    . DA  D 2 2  ? 16.64100  33.81100  29.77200  1.000 95.62957  ?  2   DA  D H62    1 
ATOM   3657 H  H2     . DA  D 2 2  ? 11.85500  33.27200  28.49000  1.000 92.10238  ?  2   DA  D H2     1 
ATOM   3658 P  P      . DT  D 2 3  ? 8.50000   32.60600  36.04800  1.000 99.57756  ?  3   DT  D P      1 
ATOM   3659 O  OP1    . DT  D 2 3  ? 7.87600   33.91600  35.74900  1.000 93.93729  ?  3   DT  D OP1    1 
ATOM   3660 O  OP2    . DT  D 2 3  ? 7.90800   31.78100  37.11900  1.000 107.29848 -1 3   DT  D OP2    1 
ATOM   3661 O  "O5'"  . DT  D 2 3  ? 8.52300   31.72300  34.70600  1.000 97.59789  ?  3   DT  D "O5'"  1 
ATOM   3662 C  "C5'"  . DT  D 2 3  ? 7.70600   32.10700  33.60200  1.000 89.21376  ?  3   DT  D "C5'"  1 
ATOM   3663 C  "C4'"  . DT  D 2 3  ? 7.87500   31.17800  32.42400  1.000 83.09071  ?  3   DT  D "C4'"  1 
ATOM   3664 O  "O4'"  . DT  D 2 3  ? 9.16200   31.40700  31.77300  1.000 82.61706  ?  3   DT  D "O4'"  1 
ATOM   3665 C  "C3'"  . DT  D 2 3  ? 7.85800   29.67000  32.74600  1.000 83.84971  ?  3   DT  D "C3'"  1 
ATOM   3666 O  "O3'"  . DT  D 2 3  ? 7.06700   28.99500  31.77600  1.000 85.12825  ?  3   DT  D "O3'"  1 
ATOM   3667 C  "C2'"  . DT  D 2 3  ? 9.33100   29.28000  32.62500  1.000 77.55463  ?  3   DT  D "C2'"  1 
ATOM   3668 C  "C1'"  . DT  D 2 3  ? 9.70000   30.13800  31.43000  1.000 77.20543  ?  3   DT  D "C1'"  1 
ATOM   3669 N  N1     . DT  D 2 3  ? 11.13700  30.24400  31.10200  1.000 74.47771  ?  3   DT  D N1     1 
ATOM   3670 C  C2     . DT  D 2 3  ? 11.48200  30.30100  29.77600  1.000 70.37917  ?  3   DT  D C2     1 
ATOM   3671 O  O2     . DT  D 2 3  ? 10.66500  30.28500  28.87500  1.000 68.12548  ?  3   DT  D O2     1 
ATOM   3672 N  N3     . DT  D 2 3  ? 12.81400  30.39300  29.53600  1.000 69.53054  ?  3   DT  D N3     1 
ATOM   3673 C  C4     . DT  D 2 3  ? 13.81900  30.41600  30.45600  1.000 69.13283  ?  3   DT  D C4     1 
ATOM   3674 O  O4     . DT  D 2 3  ? 14.99000  30.49600  30.13600  1.000 69.38606  ?  3   DT  D O4     1 
ATOM   3675 C  C5     . DT  D 2 3  ? 13.40100  30.34600  31.82300  1.000 72.18466  ?  3   DT  D C5     1 
ATOM   3676 C  C7     . DT  D 2 3  ? 14.42300  30.37200  32.90100  1.000 75.64443  ?  3   DT  D C7     1 
ATOM   3677 C  C6     . DT  D 2 3  ? 12.08900  30.26100  32.08500  1.000 73.12505  ?  3   DT  D C6     1 
ATOM   3678 H  "H5'"  . DT  D 2 3  ? 7.94500   33.00700  33.33100  1.000 107.05651 ?  3   DT  D "H5'"  1 
ATOM   3679 H  "H5''" . DT  D 2 3  ? 6.77700   32.09800  33.88000  1.000 107.05651 ?  3   DT  D "H5''" 1 
ATOM   3680 H  "H4'"  . DT  D 2 3  ? 7.17000   31.36300  31.78400  1.000 99.70885  ?  3   DT  D "H4'"  1 
ATOM   3681 H  "H3'"  . DT  D 2 3  ? 7.52700   29.50900  33.64300  1.000 100.61965 ?  3   DT  D "H3'"  1 
ATOM   3682 H  "H2'"  . DT  D 2 3  ? 9.83000   29.53800  33.41500  1.000 93.06556  ?  3   DT  D "H2'"  1 
ATOM   3683 H  "H2''" . DT  D 2 3  ? 9.43200   28.33600  32.42800  1.000 93.06556  ?  3   DT  D "H2''" 1 
ATOM   3684 H  "H1'"  . DT  D 2 3  ? 9.22800   29.80200  30.65200  1.000 92.64651  ?  3   DT  D "H1'"  1 
ATOM   3685 H  H3     . DT  D 2 3  ? 13.05100  30.43100  28.71100  1.000 83.43665  ?  3   DT  D H3     1 
ATOM   3686 H  H71    . DT  D 2 3  ? 14.21900  31.08800  33.52300  1.000 90.77331  ?  3   DT  D H71    1 
ATOM   3687 H  H72    . DT  D 2 3  ? 14.41800  29.52400  33.37200  1.000 90.77331  ?  3   DT  D H72    1 
ATOM   3688 H  H73    . DT  D 2 3  ? 15.29900  30.52100  32.51300  1.000 90.77331  ?  3   DT  D H73    1 
ATOM   3689 H  H6     . DT  D 2 3  ? 11.81400  30.21500  32.97200  1.000 87.75006  ?  3   DT  D H6     1 
ATOM   3690 P  P      . DA  D 2 4  ? 6.06700   27.81800  32.22300  1.000 81.68154  ?  4   DA  D P      1 
ATOM   3691 O  OP1    . DA  D 2 4  ? 4.92100   28.34500  33.06500  1.000 83.41794  ?  4   DA  D OP1    1 
ATOM   3692 O  OP2    . DA  D 2 4  ? 6.82000   26.66900  32.86600  1.000 78.60091  -1 4   DA  D OP2    1 
ATOM   3693 O  "O5'"  . DA  D 2 4  ? 5.41700   27.24100  30.87400  1.000 82.20645  ?  4   DA  D "O5'"  1 
ATOM   3694 C  "C5'"  . DA  D 2 4  ? 5.00900   28.15800  29.83200  1.000 74.27129  ?  4   DA  D "C5'"  1 
ATOM   3695 C  "C4'"  . DA  D 2 4  ? 5.71500   27.77900  28.55700  1.000 72.65094  ?  4   DA  D "C4'"  1 
ATOM   3696 O  "O4'"  . DA  D 2 4  ? 7.11300   28.12100  28.66300  1.000 71.48653  ?  4   DA  D "O4'"  1 
ATOM   3697 C  "C3'"  . DA  D 2 4  ? 5.65300   26.28800  28.22700  1.000 69.52879  ?  4   DA  D "C3'"  1 
ATOM   3698 O  "O3'"  . DA  D 2 4  ? 5.26800   26.12200  26.87100  1.000 65.40248  ?  4   DA  D "O3'"  1 
ATOM   3699 C  "C2'"  . DA  D 2 4  ? 7.08200   25.81000  28.44700  1.000 67.22212  ?  4   DA  D "C2'"  1 
ATOM   3700 C  "C1'"  . DA  D 2 4  ? 7.86100   27.05600  28.09000  1.000 68.08773  ?  4   DA  D "C1'"  1 
ATOM   3701 N  N9     . DA  D 2 4  ? 9.21600   27.08100  28.62200  1.000 68.67190  ?  4   DA  D N9     1 
ATOM   3702 C  C8     . DA  D 2 4  ? 9.61900   27.06100  29.93300  1.000 71.18829  ?  4   DA  D C8     1 
ATOM   3703 N  N7     . DA  D 2 4  ? 10.92000  27.08000  30.07400  1.000 67.92015  ?  4   DA  D N7     1 
ATOM   3704 C  C5     . DA  D 2 4  ? 11.40500  27.10000  28.77400  1.000 63.94854  ?  4   DA  D C5     1 
ATOM   3705 C  C6     . DA  D 2 4  ? 12.70900  27.12800  28.25300  1.000 64.19568  ?  4   DA  D C6     1 
ATOM   3706 N  N6     . DA  D 2 4  ? 13.80300  27.13100  29.00800  1.000 61.19212  ?  4   DA  D N6     1 
ATOM   3707 N  N1     . DA  D 2 4  ? 12.83900  27.14300  26.90600  1.000 62.07265  ?  4   DA  D N1     1 
ATOM   3708 C  C2     . DA  D 2 4  ? 11.73600  27.13900  26.15200  1.000 63.71439  ?  4   DA  D C2     1 
ATOM   3709 N  N3     . DA  D 2 4  ? 10.46400  27.11600  26.52900  1.000 69.43137  ?  4   DA  D N3     1 
ATOM   3710 C  C4     . DA  D 2 4  ? 10.36400  27.09800  27.86800  1.000 67.93959  ?  4   DA  D C4     1 
ATOM   3711 H  "H5'"  . DA  D 2 4  ? 5.25000   29.06400  30.08200  1.000 89.12554  ?  4   DA  D "H5'"  1 
ATOM   3712 H  "H5''" . DA  D 2 4  ? 4.04900   28.09900  29.70300  1.000 89.12554  ?  4   DA  D "H5''" 1 
ATOM   3713 H  "H4'"  . DA  D 2 4  ? 5.32500   28.27900  27.82300  1.000 87.18113  ?  4   DA  D "H4'"  1 
ATOM   3714 H  "H3'"  . DA  D 2 4  ? 5.03900   25.82800  28.82100  1.000 83.43455  ?  4   DA  D "H3'"  1 
ATOM   3715 H  "H2'"  . DA  D 2 4  ? 7.22700   25.56200  29.37300  1.000 80.66654  ?  4   DA  D "H2'"  1 
ATOM   3716 H  "H2''" . DA  D 2 4  ? 7.30100   25.07900  27.84900  1.000 80.66654  ?  4   DA  D "H2''" 1 
ATOM   3717 H  "H1'"  . DA  D 2 4  ? 7.88700   27.15900  27.12600  1.000 81.70528  ?  4   DA  D "H1'"  1 
ATOM   3718 H  H8     . DA  D 2 4  ? 9.02700   27.04600  30.65000  1.000 85.42595  ?  4   DA  D H8     1 
ATOM   3719 H  H61    . DA  D 2 4  ? 14.58000  27.12400  28.64000  1.000 73.43054  ?  4   DA  D H61    1 
ATOM   3720 H  H62    . DA  D 2 4  ? 13.73400  27.13900  29.86500  1.000 73.43054  ?  4   DA  D H62    1 
ATOM   3721 H  H2     . DA  D 2 4  ? 11.88000  27.15100  25.23300  1.000 76.45726  ?  4   DA  D H2     1 
ATOM   3722 P  P      . DA  D 2 5  ? 4.90000   24.67800  26.27100  1.000 62.74185  ?  5   DA  D P      1 
ATOM   3723 O  OP1    . DA  D 2 5  ? 3.80700   24.98900  25.29900  1.000 59.59876  ?  5   DA  D OP1    1 
ATOM   3724 O  OP2    . DA  D 2 5  ? 4.76700   23.67000  27.35200  1.000 57.05441  -1 5   DA  D OP2    1 
ATOM   3725 O  "O5'"  . DA  D 2 5  ? 6.17500   24.25800  25.44400  1.000 59.30947  ?  5   DA  D "O5'"  1 
ATOM   3726 C  "C5'"  . DA  D 2 5  ? 6.60600   25.10200  24.43500  1.000 54.61770  ?  5   DA  D "C5'"  1 
ATOM   3727 C  "C4'"  . DA  D 2 5  ? 8.04300   24.84100  24.12400  1.000 55.43523  ?  5   DA  D "C4'"  1 
ATOM   3728 O  "O4'"  . DA  D 2 5  ? 8.83800   24.86900  25.31700  1.000 61.52139  ?  5   DA  D "O4'"  1 
ATOM   3729 C  "C3'"  . DA  D 2 5  ? 8.31700   23.47800  23.50900  1.000 51.52059  ?  5   DA  D "C3'"  1 
ATOM   3730 O  "O3'"  . DA  D 2 5  ? 8.41500   23.65600  22.11000  1.000 54.87699  ?  5   DA  D "O3'"  1 
ATOM   3731 C  "C2'"  . DA  D 2 5  ? 9.63100   23.01700  24.17800  1.000 50.88757  ?  5   DA  D "C2'"  1 
ATOM   3732 C  "C1'"  . DA  D 2 5  ? 10.03200  24.20900  25.01500  1.000 53.95407  ?  5   DA  D "C1'"  1 
ATOM   3733 N  N9     . DA  D 2 5  ? 10.71300  23.93200  26.25100  1.000 57.46742  ?  5   DA  D N9     1 
ATOM   3734 C  C8     . DA  D 2 5  ? 10.17100  23.71400  27.48600  1.000 56.87763  ?  5   DA  D C8     1 
ATOM   3735 N  N7     . DA  D 2 5  ? 11.06500  23.59100  28.44000  1.000 58.75612  ?  5   DA  D N7     1 
ATOM   3736 C  C5     . DA  D 2 5  ? 12.25300  23.77800  27.78400  1.000 53.98492  ?  5   DA  D C5     1 
ATOM   3737 C  C6     . DA  D 2 5  ? 13.57700  23.77800  28.21300  1.000 50.94719  ?  5   DA  D C6     1 
ATOM   3738 N  N6     . DA  D 2 5  ? 13.93000  23.58300  29.47100  1.000 52.62765  ?  5   DA  D N6     1 
ATOM   3739 N  N1     . DA  D 2 5  ? 14.52800  23.99100  27.29300  1.000 51.47555  ?  5   DA  D N1     1 
ATOM   3740 C  C2     . DA  D 2 5  ? 14.17300  24.19300  26.02900  1.000 54.68977  ?  5   DA  D C2     1 
ATOM   3741 N  N3     . DA  D 2 5  ? 12.95300  24.22500  25.50800  1.000 53.42168  ?  5   DA  D N3     1 
ATOM   3742 C  C4     . DA  D 2 5  ? 12.04200  23.99400  26.43500  1.000 53.40743  ?  5   DA  D C4     1 
ATOM   3743 H  "H5'"  . DA  D 2 5  ? 6.50400   26.02100  24.72400  1.000 65.54124  ?  5   DA  D "H5'"  1 
ATOM   3744 H  "H5''" . DA  D 2 5  ? 6.07100   24.95300  23.63900  1.000 65.54124  ?  5   DA  D "H5''" 1 
ATOM   3745 H  "H4'"  . DA  D 2 5  ? 8.36200   25.52800  23.51800  1.000 66.52228  ?  5   DA  D "H4'"  1 
ATOM   3746 H  "H3'"  . DA  D 2 5  ? 7.59700   22.86400  23.72200  1.000 61.82470  ?  5   DA  D "H3'"  1 
ATOM   3747 H  "H2'"  . DA  D 2 5  ? 9.47500   22.24100  24.73900  1.000 61.06509  ?  5   DA  D "H2'"  1 
ATOM   3748 H  "H2''" . DA  D 2 5  ? 10.30700  22.82800  23.51000  1.000 61.06509  ?  5   DA  D "H2''" 1 
ATOM   3749 H  "H1'"  . DA  D 2 5  ? 10.58600  24.79600  24.47700  1.000 64.74489  ?  5   DA  D "H1'"  1 
ATOM   3750 H  H8     . DA  D 2 5  ? 9.25600   23.64300  27.63400  1.000 68.25316  ?  5   DA  D H8     1 
ATOM   3751 H  H61    . DA  D 2 5  ? 14.76100  23.59400  29.69100  1.000 63.15318  ?  5   DA  D H61    1 
ATOM   3752 H  H62    . DA  D 2 5  ? 13.32800  23.44500  30.07000  1.000 63.15318  ?  5   DA  D H62    1 
ATOM   3753 H  H2     . DA  D 2 5  ? 14.87100  24.34500  25.43300  1.000 65.62773  ?  5   DA  D H2     1 
ATOM   3754 P  P      . DA  D 2 6  ? 8.62200   22.42300  21.10400  1.000 58.24456  ?  6   DA  D P      1 
ATOM   3755 O  OP1    . DA  D 2 6  ? 8.49100   23.06000  19.74700  1.000 51.08545  ?  6   DA  D OP1    1 
ATOM   3756 O  OP2    . DA  D 2 6  ? 7.79400   21.29000  21.58500  1.000 43.31919  -1 6   DA  D OP2    1 
ATOM   3757 O  "O5'"  . DA  D 2 6  ? 10.13700  21.95200  21.35200  1.000 52.73197  ?  6   DA  D "O5'"  1 
ATOM   3758 C  "C5'"  . DA  D 2 6  ? 11.19800  22.72300  20.85200  1.000 49.42578  ?  6   DA  D "C5'"  1 
ATOM   3759 C  "C4'"  . DA  D 2 6  ? 12.54100  22.13800  21.26400  1.000 47.43895  ?  6   DA  D "C4'"  1 
ATOM   3760 O  "O4'"  . DA  D 2 6  ? 12.67800  22.12200  22.69800  1.000 48.84104  ?  6   DA  D "O4'"  1 
ATOM   3761 C  "C3'"  . DA  D 2 6  ? 12.78300  20.70100  20.83600  1.000 47.19847  ?  6   DA  D "C3'"  1 
ATOM   3762 O  "O3'"  . DA  D 2 6  ? 13.75900  20.71800  19.84800  1.000 45.73417  ?  6   DA  D "O3'"  1 
ATOM   3763 C  "C2'"  . DA  D 2 6  ? 13.22100  19.94600  22.10200  1.000 48.23939  ?  6   DA  D "C2'"  1 
ATOM   3764 C  "C1'"  . DA  D 2 6  ? 13.53300  21.05900  23.06400  1.000 45.16548  ?  6   DA  D "C1'"  1 
ATOM   3765 N  N9     . DA  D 2 6  ? 13.30600  20.81300  24.47400  1.000 44.28502  ?  6   DA  D N9     1 
ATOM   3766 C  C8     . DA  D 2 6  ? 12.11800  20.65700  25.12500  1.000 43.25285  ?  6   DA  D C8     1 
ATOM   3767 N  N7     . DA  D 2 6  ? 12.23900  20.52400  26.41600  1.000 46.13890  ?  6   DA  D N7     1 
ATOM   3768 C  C5     . DA  D 2 6  ? 13.60200  20.63700  26.61700  1.000 44.93345  ?  6   DA  D C5     1 
ATOM   3769 C  C6     . DA  D 2 6  ? 14.39400  20.63000  27.77900  1.000 50.68597  ?  6   DA  D C6     1 
ATOM   3770 N  N6     . DA  D 2 6  ? 13.89300  20.43900  29.00500  1.000 49.23845  ?  6   DA  D N6     1 
ATOM   3771 N  N1     . DA  D 2 6  ? 15.72300  20.76600  27.62600  1.000 48.09685  ?  6   DA  D N1     1 
ATOM   3772 C  C2     . DA  D 2 6  ? 16.20800  20.92400  26.40200  1.000 52.68628  ?  6   DA  D C2     1 
ATOM   3773 N  N3     . DA  D 2 6  ? 15.55900  20.97200  25.23500  1.000 49.82461  ?  6   DA  D N3     1 
ATOM   3774 C  C4     . DA  D 2 6  ? 14.25600  20.82300  25.42600  1.000 45.97628  ?  6   DA  D C4     1 
ATOM   3775 H  "H5'"  . DA  D 2 6  ? 11.12500  23.62700  21.19700  1.000 59.31094  ?  6   DA  D "H5'"  1 
ATOM   3776 H  "H5''" . DA  D 2 6  ? 11.14500  22.74700  19.88400  1.000 59.31094  ?  6   DA  D "H5''" 1 
ATOM   3777 H  "H4'"  . DA  D 2 6  ? 13.24500  22.69300  20.89300  1.000 56.92674  ?  6   DA  D "H4'"  1 
ATOM   3778 H  "H3'"  . DA  D 2 6  ? 11.96300  20.31700  20.48700  1.000 56.63816  ?  6   DA  D "H3'"  1 
ATOM   3779 H  "H2'"  . DA  D 2 6  ? 12.49900  19.39300  22.43900  1.000 57.88726  ?  6   DA  D "H2'"  1 
ATOM   3780 H  "H2''" . DA  D 2 6  ? 14.01200  19.41300  21.92700  1.000 57.88726  ?  6   DA  D "H2''" 1 
ATOM   3781 H  "H1'"  . DA  D 2 6  ? 14.45300  21.33700  22.93600  1.000 54.19858  ?  6   DA  D "H1'"  1 
ATOM   3782 H  H8     . DA  D 2 6  ? 11.29900  20.62000  24.68500  1.000 51.90342  ?  6   DA  D H8     1 
ATOM   3783 H  H61    . DA  D 2 6  ? 14.42000  20.40400  29.68400  1.000 59.08614  ?  6   DA  D H61    1 
ATOM   3784 H  H62    . DA  D 2 6  ? 13.04400  20.35100  29.11400  1.000 59.08614  ?  6   DA  D H62    1 
ATOM   3785 H  H2     . DA  D 2 6  ? 17.13100  21.02900  26.34900  1.000 63.22353  ?  6   DA  D H2     1 
ATOM   3786 P  P      . DA  D 2 7  ? 14.10700  19.40300  19.00800  1.000 52.39323  ?  7   DA  D P      1 
ATOM   3787 O  OP1    . DA  D 2 7  ? 14.68000  19.92900  17.73600  1.000 48.80973  ?  7   DA  D OP1    1 
ATOM   3788 O  OP2    . DA  D 2 7  ? 12.95700  18.46400  18.93000  1.000 46.48788  -1 7   DA  D OP2    1 
ATOM   3789 O  "O5'"  . DA  D 2 7  ? 15.26400  18.78800  19.89900  1.000 52.87819  ?  7   DA  D "O5'"  1 
ATOM   3790 C  "C5'"  . DA  D 2 7  ? 16.34400  19.60300  20.24000  1.000 52.30695  ?  7   DA  D "C5'"  1 
ATOM   3791 C  "C4'"  . DA  D 2 7  ? 17.24900  18.91000  21.23900  1.000 52.63392  ?  7   DA  D "C4'"  1 
ATOM   3792 O  "O4'"  . DA  D 2 7  ? 16.66900  18.94200  22.55200  1.000 47.67619  ?  7   DA  D "O4'"  1 
ATOM   3793 C  "C3'"  . DA  D 2 7  ? 17.52500  17.42800  20.95000  1.000 52.49066  ?  7   DA  D "C3'"  1 
ATOM   3794 O  "O3'"  . DA  D 2 7  ? 18.80500  17.32600  20.33500  1.000 59.19961  ?  7   DA  D "O3'"  1 
ATOM   3795 C  "C2'"  . DA  D 2 7  ? 17.43300  16.72300  22.33200  1.000 53.82434  ?  7   DA  D "C2'"  1 
ATOM   3796 C  "C1'"  . DA  D 2 7  ? 17.22200  17.86600  23.31800  1.000 50.22519  ?  7   DA  D "C1'"  1 
ATOM   3797 N  N9     . DA  D 2 7  ? 16.30400  17.64600  24.44100  1.000 45.83423  ?  7   DA  D N9     1 
ATOM   3798 C  C8     . DA  D 2 7  ? 14.92900  17.66900  24.40300  1.000 49.99206  ?  7   DA  D C8     1 
ATOM   3799 N  N7     . DA  D 2 7  ? 14.34700  17.54400  25.60900  1.000 49.84362  ?  7   DA  D N7     1 
ATOM   3800 C  C5     . DA  D 2 7  ? 15.41400  17.46400  26.46800  1.000 46.15511  ?  7   DA  D C5     1 
ATOM   3801 C  C6     . DA  D 2 7  ? 15.49300  17.30400  27.85900  1.000 50.57065  ?  7   DA  D C6     1 
ATOM   3802 N  N6     . DA  D 2 7  ? 14.42700  17.21800  28.65800  1.000 51.78225  ?  7   DA  D N6     1 
ATOM   3803 N  N1     . DA  D 2 7  ? 16.73400  17.25800  28.40800  1.000 49.02574  ?  7   DA  D N1     1 
ATOM   3804 C  C2     . DA  D 2 7  ? 17.80800  17.34300  27.61300  1.000 49.22057  ?  7   DA  D C2     1 
ATOM   3805 N  N3     . DA  D 2 7  ? 17.86500  17.48600  26.28600  1.000 49.63875  ?  7   DA  D N3     1 
ATOM   3806 C  C4     . DA  D 2 7  ? 16.63300  17.53700  25.76300  1.000 46.09323  ?  7   DA  D C4     1 
ATOM   3807 H  "H5'"  . DA  D 2 7  ? 16.01200  20.42700  20.62900  1.000 62.76834  ?  7   DA  D "H5'"  1 
ATOM   3808 H  "H5''" . DA  D 2 7  ? 16.85200  19.81000  19.44000  1.000 62.76834  ?  7   DA  D "H5''" 1 
ATOM   3809 H  "H4'"  . DA  D 2 7  ? 18.09600  19.38200  21.26500  1.000 63.16071  ?  7   DA  D "H4'"  1 
ATOM   3810 H  "H3'"  . DA  D 2 7  ? 16.84500  17.07600  20.35500  1.000 62.98879  ?  7   DA  D "H3'"  1 
ATOM   3811 H  "H2'"  . DA  D 2 7  ? 16.68000  16.11200  22.35200  1.000 64.58921  ?  7   DA  D "H2'"  1 
ATOM   3812 H  "H2''" . DA  D 2 7  ? 18.25700  16.25400  22.53000  1.000 64.58921  ?  7   DA  D "H2''" 1 
ATOM   3813 H  "H1'"  . DA  D 2 7  ? 18.08400  18.14100  23.66800  1.000 60.27023  ?  7   DA  D "H1'"  1 
ATOM   3814 H  H8     . DA  D 2 7  ? 14.44500  17.76400  23.61400  1.000 59.99048  ?  7   DA  D H8     1 
ATOM   3815 H  H61    . DA  D 2 7  ? 14.53200  17.13500  29.50800  1.000 62.13870  ?  7   DA  D H61    1 
ATOM   3816 H  H62    . DA  D 2 7  ? 13.63500  17.24600  28.32300  1.000 62.13870  ?  7   DA  D H62    1 
ATOM   3817 H  H2     . DA  D 2 7  ? 18.63000  17.30700  28.04700  1.000 59.06469  ?  7   DA  D H2     1 
ATOM   3818 P  P      . DG  D 2 8  ? 19.31800  15.96100  19.65200  1.000 68.36502  ?  8   DG  D P      1 
ATOM   3819 O  OP1    . DG  D 2 8  ? 20.63100  16.32100  19.04700  1.000 62.31738  ?  8   DG  D OP1    1 
ATOM   3820 O  OP2    . DG  D 2 8  ? 18.27000  15.27600  18.84700  1.000 66.51139  -1 8   DG  D OP2    1 
ATOM   3821 O  "O5'"  . DG  D 2 8  ? 19.58600  15.03600  20.90300  1.000 59.79401  ?  8   DG  D "O5'"  1 
ATOM   3822 C  "C5'"  . DG  D 2 8  ? 20.66700  15.35300  21.74100  1.000 55.27402  ?  8   DG  D "C5'"  1 
ATOM   3823 C  "C4'"  . DG  D 2 8  ? 20.71600  14.39600  22.90600  1.000 55.69552  ?  8   DG  D "C4'"  1 
ATOM   3824 O  "O4'"  . DG  D 2 8  ? 19.68400  14.73200  23.87400  1.000 48.39730  ?  8   DG  D "O4'"  1 
ATOM   3825 C  "C3'"  . DG  D 2 8  ? 20.45300  12.91700  22.53300  1.000 54.14285  ?  8   DG  D "C3'"  1 
ATOM   3826 O  "O3'"  . DG  D 2 8  ? 21.31900  12.05200  23.26000  1.000 57.74224  ?  8   DG  D "O3'"  1 
ATOM   3827 C  "C2'"  . DG  D 2 8  ? 19.01000  12.72100  22.97300  1.000 52.77370  ?  8   DG  D "C2'"  1 
ATOM   3828 C  "C1'"  . DG  D 2 8  ? 19.05600  13.52100  24.26400  1.000 51.87378  ?  8   DG  D "C1'"  1 
ATOM   3829 N  N9     . DG  D 2 8  ? 17.76800  13.75300  24.90000  1.000 48.83181  ?  8   DG  D N9     1 
ATOM   3830 C  C8     . DG  D 2 8  ? 16.54500  13.90400  24.30300  1.000 44.00467  ?  8   DG  D C8     1 
ATOM   3831 N  N7     . DG  D 2 8  ? 15.57500  14.07100  25.15600  1.000 46.35050  ?  8   DG  D N7     1 
ATOM   3832 C  C5     . DG  D 2 8  ? 16.18800  14.00000  26.39000  1.000 42.90786  ?  8   DG  D C5     1 
ATOM   3833 C  C6     . DG  D 2 8  ? 15.64500  14.12200  27.68200  1.000 47.65018  ?  8   DG  D C6     1 
ATOM   3834 O  O6     . DG  D 2 8  ? 14.47300  14.29400  27.99900  1.000 46.18115  ?  8   DG  D O6     1 
ATOM   3835 N  N1     . DG  D 2 8  ? 16.62000  14.01100  28.65800  1.000 48.33580  ?  8   DG  D N1     1 
ATOM   3836 C  C2     . DG  D 2 8  ? 17.95900  13.79700  28.41900  1.000 49.44274  ?  8   DG  D C2     1 
ATOM   3837 N  N2     . DG  D 2 8  ? 18.77100  13.68900  29.51300  1.000 47.62466  ?  8   DG  D N2     1 
ATOM   3838 N  N3     . DG  D 2 8  ? 18.47800  13.68800  27.21000  1.000 50.12315  ?  8   DG  D N3     1 
ATOM   3839 C  C4     . DG  D 2 8  ? 17.54200  13.80800  26.25000  1.000 48.27522  ?  8   DG  D C4     1 
ATOM   3840 H  "H5'"  . DG  D 2 8  ? 20.56200  16.25800  22.07300  1.000 66.32882  ?  8   DG  D "H5'"  1 
ATOM   3841 H  "H5''" . DG  D 2 8  ? 21.49400  15.28900  21.23700  1.000 66.32882  ?  8   DG  D "H5''" 1 
ATOM   3842 H  "H4'"  . DG  D 2 8  ? 21.58400  14.46400  23.33400  1.000 66.83463  ?  8   DG  D "H4'"  1 
ATOM   3843 H  "H3'"  . DG  D 2 8  ? 20.54500  12.78000  21.57700  1.000 64.97142  ?  8   DG  D "H3'"  1 
ATOM   3844 H  "H2'"  . DG  D 2 8  ? 18.39000  13.11000  22.33700  1.000 63.32844  ?  8   DG  D "H2'"  1 
ATOM   3845 H  "H2''" . DG  D 2 8  ? 18.81500  11.78600  23.14200  1.000 63.32844  ?  8   DG  D "H2''" 1 
ATOM   3846 H  "H1'"  . DG  D 2 8  ? 19.63300  13.06100  24.89300  1.000 62.24854  ?  8   DG  D "H1'"  1 
ATOM   3847 H  H8     . DG  D 2 8  ? 16.42200  13.90200  23.38100  1.000 52.80560  ?  8   DG  D H8     1 
ATOM   3848 H  H1     . DG  D 2 8  ? 16.36600  14.05600  29.47800  1.000 58.00296  ?  8   DG  D H1     1 
ATOM   3849 H  H21    . DG  D 2 8  ? 19.59400  13.45900  29.41700  1.000 57.14960  ?  8   DG  D H21    1 
ATOM   3850 H  H22    . DG  D 2 8  ? 18.45900  13.85100  30.29700  1.000 57.14960  ?  8   DG  D H22    1 
ATOM   3851 P  P      . DG  D 2 9  ? 22.25600  11.00400  22.50500  1.000 61.52262  ?  9   DG  D P      1 
ATOM   3852 O  OP1    . DG  D 2 9  ? 22.98600  11.80900  21.51200  1.000 56.56638  ?  9   DG  D OP1    1 
ATOM   3853 O  OP2    . DG  D 2 9  ? 21.45200  9.80500   22.15300  1.000 59.29070  -1 9   DG  D OP2    1 
ATOM   3854 O  "O5'"  . DG  D 2 9  ? 23.22300  10.49200  23.66800  1.000 57.89177  ?  9   DG  D "O5'"  1 
ATOM   3855 C  "C5'"  . DG  D 2 9  ? 23.62200  11.38500  24.67200  1.000 57.11475  ?  9   DG  D "C5'"  1 
ATOM   3856 C  "C4'"  . DG  D 2 9  ? 23.60500  10.69700  26.00200  1.000 58.30493  ?  9   DG  D "C4'"  1 
ATOM   3857 O  "O4'"  . DG  D 2 9  ? 22.33600  10.96800  26.65900  1.000 57.73202  ?  9   DG  D "O4'"  1 
ATOM   3858 C  "C3'"  . DG  D 2 9  ? 23.76000  9.17900   25.95400  1.000 63.60170  ?  9   DG  D "C3'"  1 
ATOM   3859 O  "O3'"  . DG  D 2 9  ? 24.71700  8.75000   26.95700  1.000 66.47174  ?  9   DG  D "O3'"  1 
ATOM   3860 C  "C2'"  . DG  D 2 9  ? 22.33600  8.65200   26.22000  1.000 59.35929  ?  9   DG  D "C2'"  1 
ATOM   3861 C  "C1'"  . DG  D 2 9  ? 21.70700  9.75100   27.06100  1.000 53.42262  ?  9   DG  D "C1'"  1 
ATOM   3862 N  N9     . DG  D 2 9  ? 20.26800  9.97500   26.87500  1.000 54.70102  ?  9   DG  D N9     1 
ATOM   3863 C  C8     . DG  D 2 9  ? 19.62200  10.20200  25.67500  1.000 51.51771  ?  9   DG  D C8     1 
ATOM   3864 N  N7     . DG  D 2 9  ? 18.34100  10.44300  25.80300  1.000 53.46439  ?  9   DG  D N7     1 
ATOM   3865 C  C5     . DG  D 2 9  ? 18.11600  10.40600  27.18000  1.000 50.23647  ?  9   DG  D C5     1 
ATOM   3866 C  C6     . DG  D 2 9  ? 16.91700  10.59600  27.91000  1.000 46.14928  ?  9   DG  D C6     1 
ATOM   3867 O  O6     . DG  D 2 9  ? 15.78400  10.84200  27.48100  1.000 42.20239  ?  9   DG  D O6     1 
ATOM   3868 N  N1     . DG  D 2 9  ? 17.12700  10.46300  29.27400  1.000 47.74756  ?  9   DG  D N1     1 
ATOM   3869 C  C2     . DG  D 2 9  ? 18.36100  10.18100  29.86000  1.000 51.44732  ?  9   DG  D C2     1 
ATOM   3870 N  N2     . DG  D 2 9  ? 18.38300  10.12300  31.20900  1.000 39.79699  ?  9   DG  D N2     1 
ATOM   3871 N  N3     . DG  D 2 9  ? 19.48100  9.98700   29.18200  1.000 47.69106  ?  9   DG  D N3     1 
ATOM   3872 C  C4     . DG  D 2 9  ? 19.29700  10.12800  27.85900  1.000 52.80028  ?  9   DG  D C4     1 
ATOM   3873 H  "H5'"  . DG  D 2 9  ? 23.01900  12.14100  24.69500  1.000 68.53770  ?  9   DG  D "H5'"  1 
ATOM   3874 H  "H5''" . DG  D 2 9  ? 24.52100  11.69800  24.48400  1.000 68.53770  ?  9   DG  D "H5''" 1 
ATOM   3875 H  "H4'"  . DG  D 2 9  ? 24.31900  11.06300  26.54700  1.000 69.96591  ?  9   DG  D "H4'"  1 
ATOM   3876 H  "H3'"  . DG  D 2 9  ? 24.05700  8.90200   25.07400  1.000 76.32204  ?  9   DG  D "H3'"  1 
ATOM   3877 H  "H2'"  . DG  D 2 9  ? 21.85200  8.53900   25.38700  1.000 71.23115  ?  9   DG  D "H2'"  1 
ATOM   3878 H  "H2''" . DG  D 2 9  ? 22.36700  7.81800   26.71500  1.000 71.23115  ?  9   DG  D "H2''" 1 
ATOM   3879 H  "H1'"  . DG  D 2 9  ? 21.89100  9.58700   27.99900  1.000 64.10715  ?  9   DG  D "H1'"  1 
ATOM   3880 H  H8     . DG  D 2 9  ? 20.05300  10.17000  24.85200  1.000 61.82125  ?  9   DG  D H8     1 
ATOM   3881 H  H1     . DG  D 2 9  ? 16.45000  10.56400  29.79500  1.000 57.29707  ?  9   DG  D H1     1 
ATOM   3882 H  H21    . DG  D 2 9  ? 19.11900  9.95300   31.62000  1.000 47.75638  ?  9   DG  D H21    1 
ATOM   3883 H  H22    . DG  D 2 9  ? 17.66100  10.25600  31.65700  1.000 47.75638  ?  9   DG  D H22    1 
ATOM   3884 P  P      . DA  D 2 10 ? 25.22000  7.22100   26.98200  1.000 76.73369  ?  10  DA  D P      1 
ATOM   3885 O  OP1    . DA  D 2 10 ? 26.63400  7.22900   27.42800  1.000 79.07430  ?  10  DA  D OP1    1 
ATOM   3886 O  OP2    . DA  D 2 10 ? 24.80000  6.60900   25.67900  1.000 70.23281  -1 10  DA  D OP2    1 
ATOM   3887 O  "O5'"  . DA  D 2 10 ? 24.34700  6.55600   28.13200  1.000 56.77345  ?  10  DA  D "O5'"  1 
ATOM   3888 C  "C5'"  . DA  D 2 10 ? 24.04500  7.31200   29.26500  1.000 63.15884  ?  10  DA  D "C5'"  1 
ATOM   3889 C  "C4'"  . DA  D 2 10 ? 23.02700  6.60000   30.13300  1.000 58.14270  ?  10  DA  D "C4'"  1 
ATOM   3890 O  "O4'"  . DA  D 2 10 ? 21.68700  7.07500   29.82500  1.000 57.12128  ?  10  DA  D "O4'"  1 
ATOM   3891 C  "C3'"  . DA  D 2 10 ? 22.97900  5.08200   29.96600  1.000 61.17153  ?  10  DA  D "C3'"  1 
ATOM   3892 O  "O3'"  . DA  D 2 10 ? 22.93600  4.49100   31.23300  1.000 65.39927  ?  10  DA  D "O3'"  1 
ATOM   3893 C  "C2'"  . DA  D 2 10 ? 21.69900  4.82800   29.15600  1.000 60.57674  ?  10  DA  D "C2'"  1 
ATOM   3894 C  "C1'"  . DA  D 2 10 ? 20.81100  5.96400   29.63100  1.000 58.93381  ?  10  DA  D "C1'"  1 
ATOM   3895 N  N9     . DA  D 2 10 ? 19.74700  6.35400   28.70000  1.000 53.46108  ?  10  DA  D N9     1 
ATOM   3896 C  C8     . DA  D 2 10 ? 19.84200  6.54200   27.33400  1.000 53.93147  ?  10  DA  D C8     1 
ATOM   3897 N  N7     . DA  D 2 10 ? 18.69800  6.91500   26.76200  1.000 55.03122  ?  10  DA  D N7     1 
ATOM   3898 C  C5     . DA  D 2 10 ? 17.79900  6.99300   27.83900  1.000 51.05624  ?  10  DA  D C5     1 
ATOM   3899 C  C6     . DA  D 2 10 ? 16.41500  7.34400   27.92700  1.000 43.09980  ?  10  DA  D C6     1 
ATOM   3900 N  N6     . DA  D 2 10 ? 15.66600  7.69500   26.87000  1.000 46.29941  ?  10  DA  D N6     1 
ATOM   3901 N  N1     . DA  D 2 10 ? 15.84600  7.33300   29.13700  1.000 42.61224  ?  10  DA  D N1     1 
ATOM   3902 C  C2     . DA  D 2 10 ? 16.60700  6.96600   30.20000  1.000 49.57681  ?  10  DA  D C2     1 
ATOM   3903 N  N3     . DA  D 2 10 ? 17.90800  6.61400   30.24000  1.000 45.53927  ?  10  DA  D N3     1 
ATOM   3904 C  C4     . DA  D 2 10 ? 18.44600  6.66300   29.03800  1.000 48.27514  ?  10  DA  D C4     1 
ATOM   3905 H  "H5'"  . DA  D 2 10 ? 23.68400  8.16900   28.99100  1.000 75.79061  ?  10  DA  D "H5'"  1 
ATOM   3906 H  "H5''" . DA  D 2 10 ? 24.85600  7.45600   29.77800  1.000 75.79061  ?  10  DA  D "H5''" 1 
ATOM   3907 H  "H4'"  . DA  D 2 10 ? 23.22000  6.80200   31.06200  1.000 69.77124  ?  10  DA  D "H4'"  1 
ATOM   3908 H  "H3'"  . DA  D 2 10 ? 23.75500  4.77100   29.47600  1.000 73.40583  ?  10  DA  D "H3'"  1 
ATOM   3909 H  "H2'"  . DA  D 2 10 ? 21.87200  4.89700   28.20400  1.000 72.69208  ?  10  DA  D "H2'"  1 
ATOM   3910 H  "H2''" . DA  D 2 10 ? 21.31300  3.96800   29.38000  1.000 72.69208  ?  10  DA  D "H2''" 1 
ATOM   3911 H  "H1'"  . DA  D 2 10 ? 20.41400  5.72100   30.48200  1.000 70.72058  ?  10  DA  D "H1'"  1 
ATOM   3912 H  H8     . DA  D 2 10 ? 20.62700  6.40100   26.85500  1.000 64.71777  ?  10  DA  D H8     1 
ATOM   3913 H  H61    . DA  D 2 10 ? 14.84000  7.90600   26.98000  1.000 55.55929  ?  10  DA  D H61    1 
ATOM   3914 H  H62    . DA  D 2 10 ? 16.01200  7.70900   26.08300  1.000 55.55929  ?  10  DA  D H62    1 
ATOM   3915 H  H2     . DA  D 2 10 ? 16.17000  6.96500   31.02100  1.000 59.49217  ?  10  DA  D H2     1 
ATOM   3916 P  P      . DA  D 2 11 ? 23.17400  2.92000   31.43000  1.000 72.89394  ?  11  DA  D P      1 
ATOM   3917 O  OP1    . DA  D 2 11 ? 24.25800  2.75600   32.42700  1.000 74.05464  ?  11  DA  D OP1    1 
ATOM   3918 O  OP2    . DA  D 2 11 ? 23.28600  2.32600   30.07100  1.000 71.30162  -1 11  DA  D OP2    1 
ATOM   3919 O  "O5'"  . DA  D 2 11 ? 21.78700  2.41000   32.05700  1.000 67.17561  ?  11  DA  D "O5'"  1 
ATOM   3920 C  "C5'"  . DA  D 2 11 ? 21.36500  2.88000   33.32400  1.000 65.32350  ?  11  DA  D "C5'"  1 
ATOM   3921 C  "C4'"  . DA  D 2 11 ? 19.88300  2.61500   33.53800  1.000 62.88828  ?  11  DA  D "C4'"  1 
ATOM   3922 O  "O4'"  . DA  D 2 11 ? 19.12100  3.35100   32.53800  1.000 57.87644  ?  11  DA  D "O4'"  1 
ATOM   3923 C  "C3'"  . DA  D 2 11 ? 19.46400  1.14200   33.40500  1.000 65.60656  ?  11  DA  D "C3'"  1 
ATOM   3924 O  "O3'"  . DA  D 2 11 ? 18.71500  0.72800   34.56300  1.000 69.22490  ?  11  DA  D "O3'"  1 
ATOM   3925 C  "C2'"  . DA  D 2 11 ? 18.63700  1.09100   32.11800  1.000 60.59669  ?  11  DA  D "C2'"  1 
ATOM   3926 C  "C1'"  . DA  D 2 11 ? 18.15100  2.51700   31.96200  1.000 53.35841  ?  11  DA  D "C1'"  1 
ATOM   3927 N  N9     . DA  D 2 11 ? 17.93100  2.89500   30.55600  1.000 53.65332  ?  11  DA  D N9     1 
ATOM   3928 C  C8     . DA  D 2 11 ? 18.80900  2.83700   29.51500  1.000 56.33788  ?  11  DA  D C8     1 
ATOM   3929 N  N7     . DA  D 2 11 ? 18.29100  3.22300   28.35800  1.000 54.84549  ?  11  DA  D N7     1 
ATOM   3930 C  C5     . DA  D 2 11 ? 16.98300  3.55800   28.69300  1.000 53.04097  ?  11  DA  D C5     1 
ATOM   3931 C  C6     . DA  D 2 11 ? 15.88200  4.04100   27.94500  1.000 44.95095  ?  11  DA  D C6     1 
ATOM   3932 N  N6     . DA  D 2 11 ? 15.91600  4.31000   26.65200  1.000 46.16019  ?  11  DA  D N6     1 
ATOM   3933 N  N1     . DA  D 2 11 ? 14.73100  4.26900   28.60700  1.000 42.20957  ?  11  DA  D N1     1 
ATOM   3934 C  C2     . DA  D 2 11 ? 14.68200  4.01400   29.92000  1.000 48.48573  ?  11  DA  D C2     1 
ATOM   3935 N  N3     . DA  D 2 11 ? 15.64200  3.57000   30.71800  1.000 53.14866  ?  11  DA  D N3     1 
ATOM   3936 C  C4     . DA  D 2 11 ? 16.77000  3.35900   30.04300  1.000 49.50135  ?  11  DA  D C4     1 
ATOM   3937 H  "H5'"  . DA  D 2 11 ? 21.52900  3.83400   33.38000  1.000 78.38820  ?  11  DA  D "H5'"  1 
ATOM   3938 H  "H5''" . DA  D 2 11 ? 21.87200  2.42800   34.01600  1.000 78.38820  ?  11  DA  D "H5''" 1 
ATOM   3939 H  "H4'"  . DA  D 2 11 ? 19.63200  2.93300   34.41900  1.000 75.46593  ?  11  DA  D "H4'"  1 
ATOM   3940 H  "H3'"  . DA  D 2 11 ? 20.25300  0.58600   33.30900  1.000 78.72787  ?  11  DA  D "H3'"  1 
ATOM   3941 H  "H2'"  . DA  D 2 11 ? 19.19200  0.83300   31.36600  1.000 72.71603  ?  11  DA  D "H2'"  1 
ATOM   3942 H  "H2''" . DA  D 2 11 ? 17.88900  0.48400   32.21600  1.000 72.71603  ?  11  DA  D "H2''" 1 
ATOM   3943 H  "H1'"  . DA  D 2 11 ? 17.31900  2.62000   32.44900  1.000 64.03009  ?  11  DA  D "H1'"  1 
ATOM   3944 H  H8     . DA  D 2 11 ? 19.68600  2.54200   29.60600  1.000 67.60546  ?  11  DA  D H8     1 
ATOM   3945 H  H61    . DA  D 2 11 ? 15.21700  4.62100   26.25900  1.000 55.39223  ?  11  DA  D H61    1 
ATOM   3946 H  H62    . DA  D 2 11 ? 16.63700  4.17400   26.20300  1.000 55.39223  ?  11  DA  D H62    1 
ATOM   3947 H  H2     . DA  D 2 11 ? 13.86600  4.18500   30.33100  1.000 58.18287  ?  11  DA  D H2     1 
ATOM   3948 P  P      . DG  D 2 12 ? 18.08900  -0.75600  34.68100  1.000 74.36214  ?  12  DG  D P      1 
ATOM   3949 O  OP1    . DG  D 2 12 ? 18.21000  -1.07800  36.13200  1.000 81.98546  ?  12  DG  D OP1    1 
ATOM   3950 O  OP2    . DG  D 2 12 ? 18.63000  -1.69100  33.66300  1.000 70.77812  -1 12  DG  D OP2    1 
ATOM   3951 O  "O5'"  . DG  D 2 12 ? 16.54400  -0.52600  34.32000  1.000 73.07160  ?  12  DG  D "O5'"  1 
ATOM   3952 C  "C5'"  . DG  D 2 12 ? 15.79100  0.46300   35.04200  1.000 67.56600  ?  12  DG  D "C5'"  1 
ATOM   3953 C  "C4'"  . DG  D 2 12 ? 14.36100  0.49100   34.56500  1.000 69.18711  ?  12  DG  D "C4'"  1 
ATOM   3954 O  "O4'"  . DG  D 2 12 ? 14.29400  1.07400   33.22000  1.000 54.84277  ?  12  DG  D "O4'"  1 
ATOM   3955 C  "C3'"  . DG  D 2 12 ? 13.70900  -0.88400  34.48700  1.000 63.66026  ?  12  DG  D "C3'"  1 
ATOM   3956 O  "O3'"  . DG  D 2 12 ? 12.46500  -0.84400  35.16300  1.000 61.07161  ?  12  DG  D "O3'"  1 
ATOM   3957 C  "C2'"  . DG  D 2 12 ? 13.58800  -1.16100  32.97700  1.000 62.46500  ?  12  DG  D "C2'"  1 
ATOM   3958 C  "C1'"  . DG  D 2 12 ? 13.57400  0.22700   32.35800  1.000 55.59559  ?  12  DG  D "C1'"  1 
ATOM   3959 N  N9     . DG  D 2 12 ? 14.19300  0.32900   31.03500  1.000 55.34857  ?  12  DG  D N9     1 
ATOM   3960 C  C8     . DG  D 2 12 ? 15.52200  0.16500   30.70100  1.000 56.18350  ?  12  DG  D C8     1 
ATOM   3961 N  N7     . DG  D 2 12 ? 15.76300  0.36700   29.43000  1.000 51.60911  ?  12  DG  D N7     1 
ATOM   3962 C  C5     . DG  D 2 12 ? 14.51900  0.70500   28.90500  1.000 51.95489  ?  12  DG  D C5     1 
ATOM   3963 C  C6     . DG  D 2 12 ? 14.13900  1.03600   27.58500  1.000 45.45821  ?  12  DG  D C6     1 
ATOM   3964 O  O6     . DG  D 2 12 ? 14.84400  1.10500   26.58500  1.000 47.14979  ?  12  DG  D O6     1 
ATOM   3965 N  N1     . DG  D 2 12 ? 12.77900  1.32300   27.49100  1.000 43.33249  ?  12  DG  D N1     1 
ATOM   3966 C  C2     . DG  D 2 12 ? 11.89100  1.29200   28.54500  1.000 45.71279  ?  12  DG  D C2     1 
ATOM   3967 N  N2     . DG  D 2 12 ? 10.59300  1.59500   28.26500  1.000 44.74990  ?  12  DG  D N2     1 
ATOM   3968 N  N3     . DG  D 2 12 ? 12.24200  0.98000   29.77900  1.000 47.36273  ?  12  DG  D N3     1 
ATOM   3969 C  C4     . DG  D 2 12 ? 13.55900  0.70300   29.88300  1.000 49.69239  ?  12  DG  D C4     1 
ATOM   3970 H  "H5'"  . DG  D 2 12 ? 16.19200  1.33500   34.90500  1.000 81.07919  ?  12  DG  D "H5'"  1 
ATOM   3971 H  "H5''" . DG  D 2 12 ? 15.80600  0.24900   35.98500  1.000 81.07919  ?  12  DG  D "H5''" 1 
ATOM   3972 H  "H4'"  . DG  D 2 12 ? 13.84400  1.04600   35.17000  1.000 83.02453  ?  12  DG  D "H4'"  1 
ATOM   3973 H  "H3'"  . DG  D 2 12 ? 14.28700  -1.54600  34.89800  1.000 76.39231  ?  12  DG  D "H3'"  1 
ATOM   3974 H  "H2'"  . DG  D 2 12 ? 14.35300  -1.66600  32.66200  1.000 74.95800  ?  12  DG  D "H2'"  1 
ATOM   3975 H  "H2''" . DG  D 2 12 ? 12.76300  -1.63000  32.78000  1.000 74.95800  ?  12  DG  D "H2''" 1 
ATOM   3976 H  "H1'"  . DG  D 2 12 ? 12.65700  0.53900   32.30300  1.000 66.71471  ?  12  DG  D "H1'"  1 
ATOM   3977 H  H8     . DG  D 2 12 ? 16.17500  -0.08700  31.31200  1.000 67.42020  ?  12  DG  D H8     1 
ATOM   3978 H  H1     . DG  D 2 12 ? 12.47000  1.53500   26.71700  1.000 51.99899  ?  12  DG  D H1     1 
ATOM   3979 H  H21    . DG  D 2 12 ? 10.00400  1.58300   28.89100  1.000 53.69988  ?  12  DG  D H21    1 
ATOM   3980 H  H22    . DG  D 2 12 ? 10.36300  1.79800   27.46200  1.000 53.69988  ?  12  DG  D H22    1 
ATOM   3981 P  P      . DT  D 2 13 ? 11.51200  -2.13700  35.22900  1.000 64.04233  ?  13  DT  D P      1 
ATOM   3982 O  OP1    . DT  D 2 13 ? 10.66200  -2.00100  36.43500  1.000 70.27700  ?  13  DT  D OP1    1 
ATOM   3983 O  OP2    . DT  D 2 13 ? 12.33900  -3.33900  35.01000  1.000 67.88768  -1 13  DT  D OP2    1 
ATOM   3984 O  "O5'"  . DT  D 2 13 ? 10.61600  -1.98700  33.90800  1.000 66.02199  ?  13  DT  D "O5'"  1 
ATOM   3985 C  "C5'"  . DT  D 2 13 ? 9.54500   -1.05800  33.88000  1.000 62.42198  ?  13  DT  D "C5'"  1 
ATOM   3986 C  "C4'"  . DT  D 2 13 ? 8.64500   -1.35100  32.70000  1.000 65.00925  ?  13  DT  D "C4'"  1 
ATOM   3987 O  "O4'"  . DT  D 2 13 ? 9.38400   -1.12000  31.48000  1.000 59.79025  ?  13  DT  D "O4'"  1 
ATOM   3988 C  "C3'"  . DT  D 2 13 ? 8.13200   -2.79100  32.64100  1.000 68.19683  ?  13  DT  D "C3'"  1 
ATOM   3989 O  "O3'"  . DT  D 2 13 ? 6.70200   -2.78400  32.67800  1.000 71.82446  ?  13  DT  D "O3'"  1 
ATOM   3990 C  "C2'"  . DT  D 2 13 ? 8.71300   -3.36600  31.33400  1.000 70.39243  ?  13  DT  D "C2'"  1 
ATOM   3991 C  "C1'"  . DT  D 2 13 ? 9.07000   -2.12300  30.53000  1.000 65.82996  ?  13  DT  D "C1'"  1 
ATOM   3992 N  N1     . DT  D 2 13 ? 10.26400  -2.20300  29.58400  1.000 61.10045  ?  13  DT  D N1     1 
ATOM   3993 C  C2     . DT  D 2 13 ? 10.07100  -1.88000  28.26100  1.000 59.79866  ?  13  DT  D C2     1 
ATOM   3994 O  O2     . DT  D 2 13 ? 8.98700   -1.60700  27.79800  1.000 58.92634  ?  13  DT  D O2     1 
ATOM   3995 N  N3     . DT  D 2 13 ? 11.18600  -1.91400  27.49000  1.000 52.03784  ?  13  DT  D N3     1 
ATOM   3996 C  C4     . DT  D 2 13 ? 12.47200  -2.20800  27.88500  1.000 56.23419  ?  13  DT  D C4     1 
ATOM   3997 O  O4     . DT  D 2 13 ? 13.42500  -2.20000  27.09400  1.000 54.28080  ?  13  DT  D O4     1 
ATOM   3998 C  C5     . DT  D 2 13 ? 12.62300  -2.53100  29.30000  1.000 54.97634  ?  13  DT  D C5     1 
ATOM   3999 C  C7     . DT  D 2 13 ? 13.98500  -2.87200  29.85800  1.000 53.11424  ?  13  DT  D C7     1 
ATOM   4000 C  C6     . DT  D 2 13 ? 11.52600  -2.49200  30.07000  1.000 58.33344  ?  13  DT  D C6     1 
ATOM   4001 H  "H5'"  . DT  D 2 13 ? 9.90000   -0.15900  33.79900  1.000 74.90637  ?  13  DT  D "H5'"  1 
ATOM   4002 H  "H5''" . DT  D 2 13 ? 9.03400   -1.13000  34.70100  1.000 74.90637  ?  13  DT  D "H5''" 1 
ATOM   4003 H  "H4'"  . DT  D 2 13 ? 7.88600   -0.74800  32.72700  1.000 78.01110  ?  13  DT  D "H4'"  1 
ATOM   4004 H  "H3'"  . DT  D 2 13 ? 8.47600   -3.29000  33.39800  1.000 81.83619  ?  13  DT  D "H3'"  1 
ATOM   4005 H  "H2'"  . DT  D 2 13 ? 9.50600   -3.89400  31.51600  1.000 84.47091  ?  13  DT  D "H2'"  1 
ATOM   4006 H  "H2''" . DT  D 2 13 ? 8.04700   -3.89500  30.86800  1.000 84.47091  ?  13  DT  D "H2''" 1 
ATOM   4007 H  "H1'"  . DT  D 2 13 ? 8.29000   -1.84300  30.02700  1.000 78.99595  ?  13  DT  D "H1'"  1 
ATOM   4008 H  H3     . DT  D 2 13 ? 11.07800  -1.72800  26.65700  1.000 62.44541  ?  13  DT  D H3     1 
ATOM   4009 H  H71    . DT  D 2 13 ? 13.95000  -2.86000  30.82600  1.000 63.73709  ?  13  DT  D H71    1 
ATOM   4010 H  H72    . DT  D 2 13 ? 14.24600  -3.75600  29.55500  1.000 63.73709  ?  13  DT  D H72    1 
ATOM   4011 H  H73    . DT  D 2 13 ? 14.63300  -2.22000  29.54900  1.000 63.73709  ?  13  DT  D H73    1 
ATOM   4012 H  H6     . DT  D 2 13 ? 11.61600  -2.68500  30.97500  1.000 70.00013  ?  13  DT  D H6     1 
ATOM   4013 P  P      . DG  D 2 14 ? 5.87900   -4.13700  32.93600  1.000 83.03731  ?  14  DG  D P      1 
ATOM   4014 O  OP1    . DG  D 2 14 ? 5.02700   -3.91400  34.11700  1.000 80.29483  -1 14  DG  D OP1    1 
ATOM   4015 O  OP2    . DG  D 2 14 ? 6.83300   -5.26700  32.88100  1.000 81.57153  ?  14  DG  D OP2    1 
ATOM   4016 O  "O5'"  . DG  D 2 14 ? 4.91500   -4.25300  31.67100  1.000 83.76665  ?  14  DG  D "O5'"  1 
ATOM   4017 C  "C5'"  . DG  D 2 14 ? 5.02100   -3.31100  30.59700  1.000 83.18035  ?  14  DG  D "C5'"  1 
ATOM   4018 C  "C4'"  . DG  D 2 14 ? 4.45700   -3.88000  29.31000  1.000 86.05851  ?  14  DG  D "C4'"  1 
ATOM   4019 O  "O4'"  . DG  D 2 14 ? 5.40400   -3.64200  28.21700  1.000 85.58367  ?  14  DG  D "O4'"  1 
ATOM   4020 C  "C3'"  . DG  D 2 14 ? 4.21900   -5.39600  29.29000  1.000 85.77423  ?  14  DG  D "C3'"  1 
ATOM   4021 O  "O3'"  . DG  D 2 14 ? 3.08400   -5.68200  28.46600  1.000 89.78494  ?  14  DG  D "O3'"  1 
ATOM   4022 C  "C2'"  . DG  D 2 14 ? 5.53100   -5.91400  28.68900  1.000 82.12794  ?  14  DG  D "C2'"  1 
ATOM   4023 C  "C1'"  . DG  D 2 14 ? 5.73100   -4.88500  27.59000  1.000 84.31322  ?  14  DG  D "C1'"  1 
ATOM   4024 N  N9     . DG  D 2 14 ? 7.06400   -4.78400  26.97300  1.000 79.97295  ?  14  DG  D N9     1 
ATOM   4025 C  C8     . DG  D 2 14 ? 7.32900   -4.21100  25.74100  1.000 71.67940  ?  14  DG  D C8     1 
ATOM   4026 N  N7     . DG  D 2 14 ? 8.59700   -4.25200  25.39300  1.000 70.38136  ?  14  DG  D N7     1 
ATOM   4027 C  C5     . DG  D 2 14 ? 9.21300   -4.86900  26.46700  1.000 67.24370  ?  14  DG  D C5     1 
ATOM   4028 C  C6     . DG  D 2 14 ? 10.56000  -5.16700  26.65400  1.000 64.90186  ?  14  DG  D C6     1 
ATOM   4029 O  O6     . DG  D 2 14 ? 11.48500  -4.92500  25.90400  1.000 69.08154  ?  14  DG  D O6     1 
ATOM   4030 N  N1     . DG  D 2 14 ? 10.80500  -5.81900  27.87300  1.000 79.20643  ?  14  DG  D N1     1 
ATOM   4031 C  C2     . DG  D 2 14 ? 9.84600   -6.14000  28.82200  1.000 77.68358  ?  14  DG  D C2     1 
ATOM   4032 N  N2     . DG  D 2 14 ? 10.30400  -6.79900  29.92400  1.000 74.67787  ?  14  DG  D N2     1 
ATOM   4033 N  N3     . DG  D 2 14 ? 8.52800   -5.85600  28.66500  1.000 73.02151  ?  14  DG  D N3     1 
ATOM   4034 C  C4     . DG  D 2 14 ? 8.29000   -5.21700  27.46000  1.000 75.58117  ?  14  DG  D C4     1 
ATOM   4035 H  "H5'"  . DG  D 2 14 ? 5.95400   -3.08700  30.46100  1.000 99.81642  ?  14  DG  D "H5'"  1 
ATOM   4036 H  "H5''" . DG  D 2 14 ? 4.53200   -2.50700  30.83000  1.000 99.81642  ?  14  DG  D "H5''" 1 
ATOM   4037 H  "H4'"  . DG  D 2 14 ? 3.62300   -3.42900  29.10700  1.000 103.27021 ?  14  DG  D "H4'"  1 
ATOM   4038 H  "H3'"  . DG  D 2 14 ? 4.09100   -5.74000  30.18700  1.000 102.92908 ?  14  DG  D "H3'"  1 
ATOM   4039 H  "H2'"  . DG  D 2 14 ? 6.24700   -5.88100  29.33900  1.000 98.55353  ?  14  DG  D "H2'"  1 
ATOM   4040 H  "H2''" . DG  D 2 14 ? 5.42200   -6.80400  28.32300  1.000 98.55353  ?  14  DG  D "H2''" 1 
ATOM   4041 H  "H1'"  . DG  D 2 14 ? 5.08200   -5.05600  26.88900  1.000 101.17587 ?  14  DG  D "H1'"  1 
ATOM   4042 H  H8     . DG  D 2 14 ? 6.66900   -3.83500  25.20500  1.000 86.01528  ?  14  DG  D H8     1 
ATOM   4043 H  H1     . DG  D 2 14 ? 11.61900  -6.03600  28.04700  1.000 95.04772  ?  14  DG  D H1     1 
ATOM   4044 H  H21    . DG  D 2 14 ? 9.75400   -7.04400  30.53800  1.000 89.61344  ?  14  DG  D H21    1 
ATOM   4045 H  H22    . DG  D 2 14 ? 11.14300  -6.97000  30.00500  1.000 89.61344  ?  14  DG  D H22    1 
ATOM   4046 P  P      . DG  D 2 15 ? 2.11400   -6.93500  28.74200  1.000 88.26926  ?  15  DG  D P      1 
ATOM   4047 O  OP1    . DG  D 2 15 ? 0.70100   -6.48800  29.05800  1.000 88.75129  ?  15  DG  D OP1    1 
ATOM   4048 O  OP2    . DG  D 2 15 ? 2.66900   -7.94900  29.72700  1.000 90.12159  -1 15  DG  D OP2    1 
ATOM   4049 O  "O5'"  . DG  D 2 15 ? 2.05600   -7.67600  27.31500  1.000 88.90285  ?  15  DG  D "O5'"  1 
ATOM   4050 C  "C5'"  . DG  D 2 15 ? 1.66900   -6.91800  26.14300  1.000 87.54697  ?  15  DG  D "C5'"  1 
ATOM   4051 C  "C4'"  . DG  D 2 15 ? 2.67500   -7.16500  25.05000  1.000 87.46559  ?  15  DG  D "C4'"  1 
ATOM   4052 O  "O4'"  . DG  D 2 15 ? 4.00000   -7.08500  25.60400  1.000 85.80760  ?  15  DG  D "O4'"  1 
ATOM   4053 C  "C3'"  . DG  D 2 15 ? 2.57100   -8.54400  24.40400  1.000 91.39686  ?  15  DG  D "C3'"  1 
ATOM   4054 O  "O3'"  . DG  D 2 15 ? 1.99600   -8.42600  23.10600  1.000 89.91381  ?  15  DG  D "O3'"  1 
ATOM   4055 C  "C2'"  . DG  D 2 15 ? 4.01300   -9.04100  24.30900  1.000 85.48986  ?  15  DG  D "C2'"  1 
ATOM   4056 C  "C1'"  . DG  D 2 15 ? 4.84800   -7.85900  24.77000  1.000 82.31230  ?  15  DG  D "C1'"  1 
ATOM   4057 N  N9     . DG  D 2 15 ? 6.03100   -8.22800  25.53900  1.000 80.05003  ?  15  DG  D N9     1 
ATOM   4058 C  C8     . DG  D 2 15 ? 6.08700   -8.88600  26.74100  1.000 81.65846  ?  15  DG  D C8     1 
ATOM   4059 N  N7     . DG  D 2 15 ? 7.31000   -9.06800  27.17600  1.000 80.50927  ?  15  DG  D N7     1 
ATOM   4060 C  C5     . DG  D 2 15 ? 8.10800   -8.50000  26.19200  1.000 76.64154  ?  15  DG  D C5     1 
ATOM   4061 C  C6     . DG  D 2 15 ? 9.51800   -8.39800  26.11100  1.000 76.74351  ?  15  DG  D C6     1 
ATOM   4062 O  O6     . DG  D 2 15 ? 10.36500  -8.80500  26.91800  1.000 81.81173  ?  15  DG  D O6     1 
ATOM   4063 N  N1     . DG  D 2 15 ? 9.90900   -7.74900  24.94100  1.000 74.53971  ?  15  DG  D N1     1 
ATOM   4064 C  C2     . DG  D 2 15 ? 9.06200   -7.26100  23.98100  1.000 74.45282  ?  15  DG  D C2     1 
ATOM   4065 N  N2     . DG  D 2 15 ? 9.63700   -6.66000  22.93400  1.000 73.26584  ?  15  DG  D N2     1 
ATOM   4066 N  N3     . DG  D 2 15 ? 7.73700   -7.35000  24.05100  1.000 78.63237  ?  15  DG  D N3     1 
ATOM   4067 C  C4     . DG  D 2 15 ? 7.33300   -7.98000  25.17900  1.000 77.82407  ?  15  DG  D C4     1 
ATOM   4068 H  "H5'"  . DG  D 2 15 ? 1.64900   -5.97300  26.35900  1.000 105.05637 ?  15  DG  D "H5'"  1 
ATOM   4069 H  "H5''" . DG  D 2 15 ? 0.79000   -7.20300  25.84700  1.000 105.05637 ?  15  DG  D "H5''" 1 
ATOM   4070 H  "H4'"  . DG  D 2 15 ? 2.57500   -6.48500  24.36600  1.000 104.95871 ?  15  DG  D "H4'"  1 
ATOM   4071 H  "H3'"  . DG  D 2 15 ? 2.04200   -9.13900  24.95800  1.000 109.67624 ?  15  DG  D "H3'"  1 
ATOM   4072 H  "H2'"  . DG  D 2 15 ? 4.14900   -9.80200  24.89500  1.000 102.58784 ?  15  DG  D "H2'"  1 
ATOM   4073 H  "H2''" . DG  D 2 15 ? 4.23100   -9.27300  23.39300  1.000 102.58784 ?  15  DG  D "H2''" 1 
ATOM   4074 H  "H1'"  . DG  D 2 15 ? 5.11300   -7.33100  24.00100  1.000 98.77476  ?  15  DG  D "H1'"  1 
ATOM   4075 H  H8     . DG  D 2 15 ? 5.33200   -9.16700  27.20600  1.000 97.99015  ?  15  DG  D H8     1 
ATOM   4076 H  H1     . DG  D 2 15 ? 10.75300  -7.64200  24.81300  1.000 89.44766  ?  15  DG  D H1     1 
ATOM   4077 H  H21    . DG  D 2 15 ? 9.16500   -6.44700  22.24800  1.000 87.91901  ?  15  DG  D H21    1 
ATOM   4078 H  H22    . DG  D 2 15 ? 10.47900  -6.48700  22.94700  1.000 87.91901  ?  15  DG  D H22    1 
ATOM   4079 P  P      . DG  D 2 16 ? 1.17900   -9.62800  22.41400  1.000 95.50546  ?  16  DG  D P      1 
ATOM   4080 O  OP1    . DG  D 2 16 ? 0.11000   -8.98300  21.60900  1.000 93.90141  ?  16  DG  D OP1    1 
ATOM   4081 O  OP2    . DG  D 2 16 ? 0.81900   -10.64900 23.43400  1.000 92.02781  -1 16  DG  D OP2    1 
ATOM   4082 O  "O5'"  . DG  D 2 16 ? 2.25600   -10.24100 21.39600  1.000 91.18286  ?  16  DG  D "O5'"  1 
ATOM   4083 C  "C5'"  . DG  D 2 16 ? 2.76100   -9.42200  20.32700  1.000 90.44976  ?  16  DG  D "C5'"  1 
ATOM   4084 C  "C4'"  . DG  D 2 16 ? 4.14700   -9.87400  19.87400  1.000 88.93646  ?  16  DG  D "C4'"  1 
ATOM   4085 O  "O4'"  . DG  D 2 16 ? 5.08500   -9.78600  20.97800  1.000 89.04333  ?  16  DG  D "O4'"  1 
ATOM   4086 C  "C3'"  . DG  D 2 16 ? 4.21500   -11.32100 19.37700  1.000 90.58361  ?  16  DG  D "C3'"  1 
ATOM   4087 O  "O3'"  . DG  D 2 16 ? 4.61500   -11.35800 17.99900  1.000 90.75152  ?  16  DG  D "O3'"  1 
ATOM   4088 C  "C2'"  . DG  D 2 16 ? 5.23600   -12.00400 20.30200  1.000 86.84348  ?  16  DG  D "C2'"  1 
ATOM   4089 C  "C1'"  . DG  D 2 16 ? 6.02400   -10.82800 20.86400  1.000 85.70320  ?  16  DG  D "C1'"  1 
ATOM   4090 N  N9     . DG  D 2 16 ? 6.65300   -11.06900 22.16500  1.000 79.63251  ?  16  DG  D N9     1 
ATOM   4091 C  C8     . DG  D 2 16 ? 6.05000   -11.43700 23.34900  1.000 82.65394  ?  16  DG  D C8     1 
ATOM   4092 N  N7     . DG  D 2 16 ? 6.89100   -11.57000 24.34500  1.000 81.88657  ?  16  DG  D N7     1 
ATOM   4093 C  C5     . DG  D 2 16 ? 8.12300   -11.27300 23.77900  1.000 78.84019  ?  16  DG  D C5     1 
ATOM   4094 C  C6     . DG  D 2 16 ? 9.41000   -11.24900 24.35600  1.000 78.19707  ?  16  DG  D C6     1 
ATOM   4095 O  O6     . DG  D 2 16 ? 9.73700   -11.48800 25.52300  1.000 78.54868  ?  16  DG  D O6     1 
ATOM   4096 N  N1     . DG  D 2 16 ? 10.38600  -10.89800 23.42300  1.000 75.83676  ?  16  DG  D N1     1 
ATOM   4097 C  C2     . DG  D 2 16 ? 10.13700  -10.61100 22.11100  1.000 78.17010  ?  16  DG  D C2     1 
ATOM   4098 N  N2     . DG  D 2 16 ? 11.20000  -10.29100 21.36000  1.000 79.22753  ?  16  DG  D N2     1 
ATOM   4099 N  N3     . DG  D 2 16 ? 8.93600   -10.62600 21.56400  1.000 77.52348  ?  16  DG  D N3     1 
ATOM   4100 C  C4     . DG  D 2 16 ? 7.98600   -10.95800 22.44600  1.000 77.02604  ?  16  DG  D C4     1 
ATOM   4101 H  "H5'"  . DG  D 2 16 ? 2.81200   -8.50200  20.63100  1.000 108.53971 ?  16  DG  D "H5'"  1 
ATOM   4102 H  "H5''" . DG  D 2 16 ? 2.15100   -9.47300  19.57500  1.000 108.53971 ?  16  DG  D "H5''" 1 
ATOM   4103 H  "H4'"  . DG  D 2 16 ? 4.44800   -9.28700  19.16300  1.000 106.72375 ?  16  DG  D "H4'"  1 
ATOM   4104 H  "H3'"  . DG  D 2 16 ? 3.34700   -11.74300 19.47800  1.000 108.70033 ?  16  DG  D "H3'"  1 
ATOM   4105 H  "HO3'" . DG  D 2 16 ? 5.31600   -11.76400 17.77600  1.000 108.90182 ?  16  DG  D "HO3'" 1 
ATOM   4106 H  "H2'"  . DG  D 2 16 ? 4.78600   -12.48700 21.01300  1.000 104.21218 ?  16  DG  D "H2'"  1 
ATOM   4107 H  "H2''" . DG  D 2 16 ? 5.81400   -12.59300 19.79600  1.000 104.21218 ?  16  DG  D "H2''" 1 
ATOM   4108 H  "H1'"  . DG  D 2 16 ? 6.70600   -10.57000 20.22500  1.000 102.84384 ?  16  DG  D "H1'"  1 
ATOM   4109 H  H8     . DG  D 2 16 ? 5.13400   -11.57100 23.43400  1.000 99.18473  ?  16  DG  D H8     1 
ATOM   4110 H  H1     . DG  D 2 16 ? 11.20100  -10.85800 23.69300  1.000 91.00411  ?  16  DG  D H1     1 
ATOM   4111 H  H21    . DG  D 2 16 ? 11.09700  -10.10500 20.52700  1.000 95.07304  ?  16  DG  D H21    1 
ATOM   4112 H  H22    . DG  D 2 16 ? 11.98500  -10.27200 21.71100  1.000 95.07304  ?  16  DG  D H22    1 
ATOM   4113 O  "O5'"  . DT  E 3 1  ? 17.23200  -18.77000 -4.27500  1.000 81.60643  ?  17  DT  E "O5'"  1 
ATOM   4114 C  "C5'"  . DT  E 3 1  ? 16.76200  -17.75800 -3.37700  1.000 86.51742  ?  17  DT  E "C5'"  1 
ATOM   4115 C  "C4'"  . DT  E 3 1  ? 16.59800  -18.32000 -1.96000  1.000 86.16472  ?  17  DT  E "C4'"  1 
ATOM   4116 O  "O4'"  . DT  E 3 1  ? 17.74700  -19.12900 -1.62500  1.000 78.68571  ?  17  DT  E "O4'"  1 
ATOM   4117 C  "C3'"  . DT  E 3 1  ? 16.49200  -17.26500 -0.87100  1.000 90.59513  ?  17  DT  E "C3'"  1 
ATOM   4118 O  "O3'"  . DT  E 3 1  ? 15.13700  -17.04500 -0.53800  1.000 104.01764 ?  17  DT  E "O3'"  1 
ATOM   4119 C  "C2'"  . DT  E 3 1  ? 17.26900  -17.82800 0.31500   1.000 82.34888  ?  17  DT  E "C2'"  1 
ATOM   4120 C  "C1'"  . DT  E 3 1  ? 18.18000  -18.87100 -0.30200  1.000 76.56806  ?  17  DT  E "C1'"  1 
ATOM   4121 N  N1     . DT  E 3 1  ? 19.62900  -18.49000 -0.36600  1.000 70.63258  ?  17  DT  E N1     1 
ATOM   4122 C  C2     . DT  E 3 1  ? 20.33800  -18.32600 0.79700   1.000 70.30885  ?  17  DT  E C2     1 
ATOM   4123 O  O2     . DT  E 3 1  ? 19.84500  -18.42000 1.90500   1.000 73.78779  ?  17  DT  E O2     1 
ATOM   4124 N  N3     . DT  E 3 1  ? 21.65900  -18.03100 0.61900   1.000 69.91386  ?  17  DT  E N3     1 
ATOM   4125 C  C4     . DT  E 3 1  ? 22.32900  -17.89800 -0.57700  1.000 69.39241  ?  17  DT  E C4     1 
ATOM   4126 O  O4     . DT  E 3 1  ? 23.52500  -17.63200 -0.63800  1.000 68.73311  ?  17  DT  E O4     1 
ATOM   4127 C  C5     . DT  E 3 1  ? 21.52600  -18.08800 -1.75400  1.000 67.86038  ?  17  DT  E C5     1 
ATOM   4128 C  C7     . DT  E 3 1  ? 22.14100  -17.96300 -3.09800  1.000 68.35383  ?  17  DT  E C7     1 
ATOM   4129 C  C6     . DT  E 3 1  ? 20.23700  -18.38000 -1.59700  1.000 69.41458  ?  17  DT  E C6     1 
ATOM   4130 H  "H5'"  . DT  E 3 1  ? 15.90600  -17.42700 -3.69000  1.000 103.82090 ?  17  DT  E "H5'"  1 
ATOM   4131 H  "H5''" . DT  E 3 1  ? 17.39900  -17.02700 -3.35900  1.000 103.82090 ?  17  DT  E "H5''" 1 
ATOM   4132 H  "H4'"  . DT  E 3 1  ? 15.80400  -18.87700 -1.93400  1.000 103.39766 ?  17  DT  E "H4'"  1 
ATOM   4133 H  "H3'"  . DT  E 3 1  ? 16.89900  -16.43700 -1.17100  1.000 108.71415 ?  17  DT  E "H3'"  1 
ATOM   4134 H  "H2'"  . DT  E 3 1  ? 17.79100  -17.13000 0.74100   1.000 98.81865  ?  17  DT  E "H2'"  1 
ATOM   4135 H  "H2''" . DT  E 3 1  ? 16.66500  -18.24000 0.95200   1.000 98.81865  ?  17  DT  E "H2''" 1 
ATOM   4136 H  "H1'"  . DT  E 3 1  ? 18.10100  -19.69000 0.21200   1.000 91.88167  ?  17  DT  E "H1'"  1 
ATOM   4137 H  H3     . DT  E 3 1  ? 22.12100  -17.91400 1.32800   1.000 83.89663  ?  17  DT  E H3     1 
ATOM   4138 H  H71    . DT  E 3 1  ? 22.04300  -18.80100 -3.57700  1.000 82.02459  ?  17  DT  E H71    1 
ATOM   4139 H  H72    . DT  E 3 1  ? 21.69800  -17.25500 -3.59100  1.000 82.02459  ?  17  DT  E H72    1 
ATOM   4140 H  H73    . DT  E 3 1  ? 23.08300  -17.75200 -3.00500  1.000 82.02459  ?  17  DT  E H73    1 
ATOM   4141 H  H6     . DT  E 3 1  ? 19.72100  -18.51500 -2.35800  1.000 83.29749  ?  17  DT  E H6     1 
ATOM   4142 H  "HO5'" . DT  E 3 1  ? 17.04300  -19.57600 -4.13500  1.000 97.92772  ?  17  DT  E "HO5'" 1 
ATOM   4143 P  P      . DC  E 3 2  ? 14.59000  -15.55100 -0.41500  1.000 100.02699 ?  18  DC  E P      1 
ATOM   4144 O  OP1    . DC  E 3 2  ? 13.12900  -15.64100 -0.19000  1.000 98.51275  ?  18  DC  E OP1    1 
ATOM   4145 O  OP2    . DC  E 3 2  ? 15.18600  -14.81100 -1.55800  1.000 95.68393  -1 18  DC  E OP2    1 
ATOM   4146 O  "O5'"  . DC  E 3 2  ? 15.28400  -15.00700 0.91000   1.000 92.56577  ?  18  DC  E "O5'"  1 
ATOM   4147 C  "C5'"  . DC  E 3 2  ? 15.13800  -15.72200 2.14300   1.000 91.90892  ?  18  DC  E "C5'"  1 
ATOM   4148 C  "C4'"  . DC  E 3 2  ? 16.11300  -15.18000 3.18800   1.000 88.57512  ?  18  DC  E "C4'"  1 
ATOM   4149 O  "O4'"  . DC  E 3 2  ? 17.46300  -15.55800 2.81400   1.000 87.52310  ?  18  DC  E "O4'"  1 
ATOM   4150 C  "C3'"  . DC  E 3 2  ? 16.09700  -13.65600 3.32400   1.000 81.40289  ?  18  DC  E "C3'"  1 
ATOM   4151 O  "O3'"  . DC  E 3 2  ? 15.69300  -13.26900 4.63900   1.000 89.10401  ?  18  DC  E "O3'"  1 
ATOM   4152 C  "C2'"  . DC  E 3 2  ? 17.52000  -13.20200 2.99900   1.000 80.04191  ?  18  DC  E "C2'"  1 
ATOM   4153 C  "C1'"  . DC  E 3 2  ? 18.34700  -14.48400 3.03000   1.000 79.35024  ?  18  DC  E "C1'"  1 
ATOM   4154 N  N1     . DC  E 3 2  ? 19.42700  -14.53100 1.97600   1.000 72.59156  ?  18  DC  E N1     1 
ATOM   4155 C  C2     . DC  E 3 2  ? 20.77100  -14.54600 2.36700   1.000 74.62736  ?  18  DC  E C2     1 
ATOM   4156 O  O2     . DC  E 3 2  ? 21.05100  -14.53100 3.57900   1.000 75.09066  ?  18  DC  E O2     1 
ATOM   4157 N  N3     . DC  E 3 2  ? 21.73400  -14.58100 1.41200   1.000 74.08162  ?  18  DC  E N3     1 
ATOM   4158 C  C4     . DC  E 3 2  ? 21.39100  -14.60500 0.11100   1.000 71.70072  ?  18  DC  E C4     1 
ATOM   4159 N  N4     . DC  E 3 2  ? 22.38000  -14.64200 -0.79500  1.000 69.22829  ?  18  DC  E N4     1 
ATOM   4160 C  C5     . DC  E 3 2  ? 20.02600  -14.58800 -0.30500  1.000 70.67825  ?  18  DC  E C5     1 
ATOM   4161 C  C6     . DC  E 3 2  ? 19.08700  -14.54700 0.65200   1.000 75.24456  ?  18  DC  E C6     1 
ATOM   4162 H  "H5'"  . DC  E 3 2  ? 15.32000  -16.66300 1.99200   1.000 110.29070 ?  18  DC  E "H5'"  1 
ATOM   4163 H  "H5''" . DC  E 3 2  ? 14.23000  -15.61900 2.46800   1.000 110.29070 ?  18  DC  E "H5''" 1 
ATOM   4164 H  "H4'"  . DC  E 3 2  ? 15.90300  -15.57500 4.04900   1.000 106.29014 ?  18  DC  E "H4'"  1 
ATOM   4165 H  "H3'"  . DC  E 3 2  ? 15.48300  -13.28100 2.67400   1.000 97.68346  ?  18  DC  E "H3'"  1 
ATOM   4166 H  "H2'"  . DC  E 3 2  ? 17.55300  -12.79800 2.11800   1.000 96.05029  ?  18  DC  E "H2'"  1 
ATOM   4167 H  "H2''" . DC  E 3 2  ? 17.83800  -12.57800 3.67000   1.000 96.05029  ?  18  DC  E "H2''" 1 
ATOM   4168 H  "H1'"  . DC  E 3 2  ? 18.75100  -14.57900 3.90600   1.000 95.22029  ?  18  DC  E "H1'"  1 
ATOM   4169 H  H41    . DC  E 3 2  ? 22.19400  -14.65800 -1.63400  1.000 83.07394  ?  18  DC  E H41    1 
ATOM   4170 H  H42    . DC  E 3 2  ? 23.20000  -14.65000 -0.53600  1.000 83.07394  ?  18  DC  E H42    1 
ATOM   4171 H  H5     . DC  E 3 2  ? 19.79600  -14.60000 -1.20600  1.000 84.81391  ?  18  DC  E H5     1 
ATOM   4172 H  H6     . DC  E 3 2  ? 18.18900  -14.53600 0.41100   1.000 90.29347  ?  18  DC  E H6     1 
ATOM   4173 P  P      . DC  E 3 3  ? 15.34800  -11.73200 4.96800   1.000 92.23029  ?  19  DC  E P      1 
ATOM   4174 O  OP1    . DC  E 3 3  ? 14.32800  -11.70100 6.03600   1.000 87.63920  ?  19  DC  E OP1    1 
ATOM   4175 O  OP2    . DC  E 3 3  ? 15.09800  -11.01600 3.69200   1.000 86.67315  -1 19  DC  E OP2    1 
ATOM   4176 O  "O5'"  . DC  E 3 3  ? 16.72700  -11.15900 5.53900   1.000 81.60901  ?  19  DC  E "O5'"  1 
ATOM   4177 C  "C5'"  . DC  E 3 3  ? 17.53700  -11.96300 6.40600   1.000 81.60985  ?  19  DC  E "C5'"  1 
ATOM   4178 C  "C4'"  . DC  E 3 3  ? 18.85200  -11.26100 6.71900   1.000 80.74826  ?  19  DC  E "C4'"  1 
ATOM   4179 O  "O4'"  . DC  E 3 3  ? 19.82600  -11.52500 5.66300   1.000 76.45407  ?  19  DC  E "O4'"  1 
ATOM   4180 C  "C3'"  . DC  E 3 3  ? 18.73600  -9.73900  6.83200   1.000 77.95396  ?  19  DC  E "C3'"  1 
ATOM   4181 O  "O3'"  . DC  E 3 3  ? 19.44200  -9.27800  7.97600   1.000 81.04984  ?  19  DC  E "O3'"  1 
ATOM   4182 C  "C2'"  . DC  E 3 3  ? 19.32700  -9.22700  5.52000   1.000 76.65799  ?  19  DC  E "C2'"  1 
ATOM   4183 C  "C1'"  . DC  E 3 3  ? 20.35100  -10.30800 5.16200   1.000 76.13161  ?  19  DC  E "C1'"  1 
ATOM   4184 N  N1     . DC  E 3 3  ? 20.61000  -10.49200 3.67300   1.000 72.70319  ?  19  DC  E N1     1 
ATOM   4185 C  C2     . DC  E 3 3  ? 21.92600  -10.71800 3.21200   1.000 69.24120  ?  19  DC  E C2     1 
ATOM   4186 O  O2     . DC  E 3 3  ? 22.85800  -10.74300 4.03500   1.000 66.82866  ?  19  DC  E O2     1 
ATOM   4187 N  N3     . DC  E 3 3  ? 22.13200  -10.90400 1.88400   1.000 67.32841  ?  19  DC  E N3     1 
ATOM   4188 C  C4     . DC  E 3 3  ? 21.09100  -10.86200 1.04400   1.000 68.24443  ?  19  DC  E C4     1 
ATOM   4189 N  N4     . DC  E 3 3  ? 21.32400  -11.04000 -0.25100  1.000 68.52697  ?  19  DC  E N4     1 
ATOM   4190 C  C5     . DC  E 3 3  ? 19.76000  -10.63200 1.49400   1.000 69.66288  ?  19  DC  E C5     1 
ATOM   4191 C  C6     . DC  E 3 3  ? 19.56700  -10.46100 2.79900   1.000 70.14131  ?  19  DC  E C6     1 
ATOM   4192 H  "H5'"  . DC  E 3 3  ? 17.72300  -12.81100 5.97400   1.000 97.93182  ?  19  DC  E "H5'"  1 
ATOM   4193 H  "H5''" . DC  E 3 3  ? 17.05700  -12.12400 7.23300   1.000 97.93182  ?  19  DC  E "H5''" 1 
ATOM   4194 H  "H4'"  . DC  E 3 3  ? 19.19800  -11.60900 7.55600   1.000 96.89791  ?  19  DC  E "H4'"  1 
ATOM   4195 H  "H3'"  . DC  E 3 3  ? 17.80300  -9.48300  6.89500   1.000 93.54475  ?  19  DC  E "H3'"  1 
ATOM   4196 H  "H2'"  . DC  E 3 3  ? 18.64000  -9.16100  4.84100   1.000 91.98958  ?  19  DC  E "H2'"  1 
ATOM   4197 H  "H2''" . DC  E 3 3  ? 19.76400  -8.37200  5.65200   1.000 91.98958  ?  19  DC  E "H2''" 1 
ATOM   4198 H  "H1'"  . DC  E 3 3  ? 21.18700  -10.11600 5.60800   1.000 91.35793  ?  19  DC  E "H1'"  1 
ATOM   4199 H  H41    . DC  E 3 3  ? 20.67300  -11.01800 -0.81200  1.000 82.23237  ?  19  DC  E H41    1 
ATOM   4200 H  H42    . DC  E 3 3  ? 22.12600  -11.17800 -0.52900  1.000 82.23237  ?  19  DC  E H42    1 
ATOM   4201 H  H5     . DC  E 3 3  ? 19.04800  -10.61300 0.89700   1.000 83.59546  ?  19  DC  E H5     1 
ATOM   4202 H  H6     . DC  E 3 3  ? 18.70600  -10.31700 3.11900   1.000 84.16957  ?  19  DC  E H6     1 
ATOM   4203 P  P      . DC  E 3 4  ? 19.56100  -7.72000  8.35800   1.000 83.12743  ?  20  DC  E P      1 
ATOM   4204 O  OP1    . DC  E 3 4  ? 19.55900  -7.49900  9.85700   1.000 83.62931  ?  20  DC  E OP1    1 
ATOM   4205 O  OP2    . DC  E 3 4  ? 18.60900  -6.81000  7.60200   1.000 79.61525  -1 20  DC  E OP2    1 
ATOM   4206 O  "O5'"  . DC  E 3 4  ? 21.04700  -7.37800  7.84300   1.000 75.25734  ?  20  DC  E "O5'"  1 
ATOM   4207 C  "C5'"  . DC  E 3 4  ? 22.06500  -8.40700  7.92600   1.000 77.15027  ?  20  DC  E "C5'"  1 
ATOM   4208 C  "C4'"  . DC  E 3 4  ? 23.44800  -7.79900  7.92700   1.000 71.47662  ?  20  DC  E "C4'"  1 
ATOM   4209 O  "O4'"  . DC  E 3 4  ? 24.04600  -7.97200  6.62300   1.000 74.40049  ?  20  DC  E "O4'"  1 
ATOM   4210 C  "C3'"  . DC  E 3 4  ? 23.54100  -6.30700  8.22600   1.000 68.25572  ?  20  DC  E "C3'"  1 
ATOM   4211 O  "O3'"  . DC  E 3 4  ? 24.76300  -6.07500  8.91800   1.000 67.51860  ?  20  DC  E "O3'"  1 
ATOM   4212 C  "C2'"  . DC  E 3 4  ? 23.51200  -5.67400  6.84100   1.000 65.05326  ?  20  DC  E "C2'"  1 
ATOM   4213 C  "C1'"  . DC  E 3 4  ? 24.12700  -6.73700  5.94100   1.000 64.71587  ?  20  DC  E "C1'"  1 
ATOM   4214 N  N1     . DC  E 3 4  ? 23.43700  -6.93300  4.63800   1.000 57.84513  ?  20  DC  E N1     1 
ATOM   4215 C  C2     . DC  E 3 4  ? 24.17400  -6.97300  3.44700   1.000 57.71950  ?  20  DC  E C2     1 
ATOM   4216 O  O2     . DC  E 3 4  ? 25.40500  -6.81800  3.47500   1.000 61.78886  ?  20  DC  E O2     1 
ATOM   4217 N  N3     . DC  E 3 4  ? 23.51700  -7.16900  2.27800   1.000 57.47296  ?  20  DC  E N3     1 
ATOM   4218 C  C4     . DC  E 3 4  ? 22.19000  -7.33500  2.26000   1.000 59.90367  ?  20  DC  E C4     1 
ATOM   4219 N  N4     . DC  E 3 4  ? 21.59800  -7.51800  1.09000   1.000 59.95407  ?  20  DC  E N4     1 
ATOM   4220 C  C5     . DC  E 3 4  ? 21.43100  -7.30900  3.45500   1.000 60.54998  ?  20  DC  E C5     1 
ATOM   4221 C  C6     . DC  E 3 4  ? 22.08900  -7.12000  4.60600   1.000 64.13141  ?  20  DC  E C6     1 
ATOM   4222 H  "H5'"  . DC  E 3 4  ? 21.98100  -9.00000  7.16800   1.000 92.58033  ?  20  DC  E "H5'"  1 
ATOM   4223 H  "H5''" . DC  E 3 4  ? 21.93900  -8.91400  8.74300   1.000 92.58033  ?  20  DC  E "H5''" 1 
ATOM   4224 H  "H4'"  . DC  E 3 4  ? 23.98900  -8.27400  8.57700   1.000 85.77194  ?  20  DC  E "H4'"  1 
ATOM   4225 H  "H3'"  . DC  E 3 4  ? 22.78300  -6.01400  8.75500   1.000 81.90687  ?  20  DC  E "H3'"  1 
ATOM   4226 H  "H2'"  . DC  E 3 4  ? 22.60000  -5.48300  6.57500   1.000 78.06392  ?  20  DC  E "H2'"  1 
ATOM   4227 H  "H2''" . DC  E 3 4  ? 24.04800  -4.86600  6.82600   1.000 78.06392  ?  20  DC  E "H2''" 1 
ATOM   4228 H  "H1'"  . DC  E 3 4  ? 25.05900  -6.52100  5.78200   1.000 77.65905  ?  20  DC  E "H1'"  1 
ATOM   4229 H  H41    . DC  E 3 4  ? 20.74600  -7.62700  1.05200   1.000 71.94488  ?  20  DC  E H41    1 
ATOM   4230 H  H42    . DC  E 3 4  ? 22.06600  -7.52800  0.36800   1.000 71.94488  ?  20  DC  E H42    1 
ATOM   4231 H  H5     . DC  E 3 4  ? 20.50800  -7.42400  3.44200   1.000 72.65998  ?  20  DC  E H5     1 
ATOM   4232 H  H6     . DC  E 3 4  ? 21.61000  -7.09600  5.40300   1.000 76.95770  ?  20  DC  E H6     1 
ATOM   4233 P  P      . DA  E 3 5  ? 25.09900  -4.66500  9.61600   1.000 70.63204  ?  21  DA  E P      1 
ATOM   4234 O  OP1    . DA  E 3 5  ? 26.13600  -4.90500  10.66000  1.000 71.67672  ?  21  DA  E OP1    1 
ATOM   4235 O  OP2    . DA  E 3 5  ? 23.82800  -3.91500  9.83600   1.000 62.02918  -1 21  DA  E OP2    1 
ATOM   4236 O  "O5'"  . DA  E 3 5  ? 25.83900  -3.95900  8.37800   1.000 65.76136  ?  21  DA  E "O5'"  1 
ATOM   4237 C  "C5'"  . DA  E 3 5  ? 27.03200  -4.50000  7.91200   1.000 60.81255  ?  21  DA  E "C5'"  1 
ATOM   4238 C  "C4'"  . DA  E 3 5  ? 27.52000  -3.72900  6.70500   1.000 54.29199  ?  21  DA  E "C4'"  1 
ATOM   4239 O  "O4'"  . DA  E 3 5  ? 26.73500  -4.08500  5.51100   1.000 50.80077  ?  21  DA  E "O4'"  1 
ATOM   4240 C  "C3'"  . DA  E 3 5  ? 27.38600  -2.20900  6.82800   1.000 45.22554  ?  21  DA  E "C3'"  1 
ATOM   4241 O  "O3'"  . DA  E 3 5  ? 28.50000  -1.60200  6.21400   1.000 44.48417  ?  21  DA  E "O3'"  1 
ATOM   4242 C  "C2'"  . DA  E 3 5  ? 26.06700  -1.94100  6.10700   1.000 46.28017  ?  21  DA  E "C2'"  1 
ATOM   4243 C  "C1'"  . DA  E 3 5  ? 26.21500  -2.91100  4.94000   1.000 44.69790  ?  21  DA  E "C1'"  1 
ATOM   4244 N  N9     . DA  E 3 5  ? 24.99500  -3.20700  4.21900   1.000 45.00232  ?  21  DA  E N9     1 
ATOM   4245 C  C8     . DA  E 3 5  ? 23.70600  -3.02600  4.62300   1.000 42.22648  ?  21  DA  E C8     1 
ATOM   4246 N  N7     . DA  E 3 5  ? 22.81400  -3.36000  3.70700   1.000 44.30006  ?  21  DA  E N7     1 
ATOM   4247 C  C5     . DA  E 3 5  ? 23.58400  -3.77800  2.62400   1.000 46.35017  ?  21  DA  E C5     1 
ATOM   4248 C  C6     . DA  E 3 5  ? 23.26200  -4.24300  1.32500   1.000 42.41028  ?  21  DA  E C6     1 
ATOM   4249 N  N6     . DA  E 3 5  ? 22.01900  -4.38700  0.86800   1.000 42.57470  ?  21  DA  E N6     1 
ATOM   4250 N  N1     . DA  E 3 5  ? 24.28100  -4.55400  0.51100   1.000 47.08328  ?  21  DA  E N1     1 
ATOM   4251 C  C2     . DA  E 3 5  ? 25.52800  -4.39600  0.94500   1.000 45.57984  ?  21  DA  E C2     1 
ATOM   4252 N  N3     . DA  E 3 5  ? 25.94700  -3.95900  2.12500   1.000 44.53464  ?  21  DA  E N3     1 
ATOM   4253 C  C4     . DA  E 3 5  ? 24.92600  -3.66500  2.91800   1.000 44.93506  ?  21  DA  E C4     1 
ATOM   4254 H  "H5'"  . DA  E 3 5  ? 26.88900  -5.42700  7.66400   1.000 72.97506  ?  21  DA  E "H5'"  1 
ATOM   4255 H  "H5''" . DA  E 3 5  ? 27.70000  -4.45500  8.61300   1.000 72.97506  ?  21  DA  E "H5''" 1 
ATOM   4256 H  "H4'"  . DA  E 3 5  ? 28.45100  -3.95000  6.54600   1.000 65.15038  ?  21  DA  E "H4'"  1 
ATOM   4257 H  "H3'"  . DA  E 3 5  ? 27.32400  -1.94800  7.76000   1.000 54.27065  ?  21  DA  E "H3'"  1 
ATOM   4258 H  "H2'"  . DA  E 3 5  ? 25.30900  -2.17400  6.66500   1.000 55.53620  ?  21  DA  E "H2'"  1 
ATOM   4259 H  "H2''" . DA  E 3 5  ? 26.01400  -1.02300  5.79800   1.000 55.53620  ?  21  DA  E "H2''" 1 
ATOM   4260 H  "H1'"  . DA  E 3 5  ? 26.86600  -2.55200  4.31700   1.000 53.63749  ?  21  DA  E "H1'"  1 
ATOM   4261 H  H8     . DA  E 3 5  ? 23.47600  -2.71600  5.46900   1.000 50.67178  ?  21  DA  E H8     1 
ATOM   4262 H  H61    . DA  E 3 5  ? 21.88500  -4.67300  0.06800   1.000 51.08964  ?  21  DA  E H61    1 
ATOM   4263 H  H62    . DA  E 3 5  ? 21.35000  -4.19400  1.37300   1.000 51.08964  ?  21  DA  E H62    1 
ATOM   4264 H  H2     . DA  E 3 5  ? 26.19600  -4.62300  0.34000   1.000 54.69581  ?  21  DA  E H2     1 
ATOM   4265 P  P      . DC  E 3 6  ? 28.89300  -0.10200  6.56300   1.000 44.51461  ?  22  DC  E P      1 
ATOM   4266 O  OP1    . DC  E 3 6  ? 30.21800  0.22500   6.05300   1.000 38.19930  ?  22  DC  E OP1    1 
ATOM   4267 O  OP2    . DC  E 3 6  ? 28.62800  0.05400   8.04800   1.000 41.90687  -1 22  DC  E OP2    1 
ATOM   4268 O  "O5'"  . DC  E 3 6  ? 27.78500  0.72700   5.77900   1.000 38.52530  ?  22  DC  E "O5'"  1 
ATOM   4269 C  "C5'"  . DC  E 3 6  ? 28.11800  1.43900   4.61700   1.000 43.36105  ?  22  DC  E "C5'"  1 
ATOM   4270 C  "C4'"  . DC  E 3 6  ? 28.23500  0.50300   3.40400   1.000 37.99315  ?  22  DC  E "C4'"  1 
ATOM   4271 O  "O4'"  . DC  E 3 6  ? 26.96100  -0.21100  3.22400   1.000 33.38797  ?  22  DC  E "O4'"  1 
ATOM   4272 C  "C3'"  . DC  E 3 6  ? 28.51700  1.22800   2.07400   1.000 39.95534  ?  22  DC  E "C3'"  1 
ATOM   4273 O  "O3'"  . DC  E 3 6  ? 29.71700  0.73100   1.43900   1.000 40.94272  ?  22  DC  E "O3'"  1 
ATOM   4274 C  "C2'"  . DC  E 3 6  ? 27.27000  0.95500   1.23100   1.000 37.85493  ?  22  DC  E "C2'"  1 
ATOM   4275 C  "C1'"  . DC  E 3 6  ? 26.70700  -0.31900  1.83900   1.000 36.51380  ?  22  DC  E "C1'"  1 
ATOM   4276 N  N1     . DC  E 3 6  ? 25.27700  -0.47900  1.63600   1.000 36.82420  ?  22  DC  E N1     1 
ATOM   4277 C  C2     . DC  E 3 6  ? 24.78500  -1.02400  0.42400   1.000 36.97555  ?  22  DC  E C2     1 
ATOM   4278 O  O2     . DC  E 3 6  ? 25.56100  -1.38500  -0.42300  1.000 42.41700  ?  22  DC  E O2     1 
ATOM   4279 N  N3     . DC  E 3 6  ? 23.44500  -1.15700  0.25800   1.000 39.82564  ?  22  DC  E N3     1 
ATOM   4280 C  C4     . DC  E 3 6  ? 22.60400  -0.74900  1.23500   1.000 37.46445  ?  22  DC  E C4     1 
ATOM   4281 N  N4     . DC  E 3 6  ? 21.28800  -0.89300  1.02900   1.000 40.72931  ?  22  DC  E N4     1 
ATOM   4282 C  C5     . DC  E 3 6  ? 23.08700  -0.17400  2.45300   1.000 36.96891  ?  22  DC  E C5     1 
ATOM   4283 C  C6     . DC  E 3 6  ? 24.41500  -0.05200  2.60300   1.000 35.38856  ?  22  DC  E C6     1 
ATOM   4284 H  "H5'"  . DC  E 3 6  ? 28.96500  1.89100   4.75300   1.000 52.03326  ?  22  DC  E "H5'"  1 
ATOM   4285 H  "H5''" . DC  E 3 6  ? 27.43000  2.10000   4.44200   1.000 52.03326  ?  22  DC  E "H5''" 1 
ATOM   4286 H  "H4'"  . DC  E 3 6  ? 28.94000  -0.14300  3.56900   1.000 45.59178  ?  22  DC  E "H4'"  1 
ATOM   4287 H  "H3'"  . DC  E 3 6  ? 28.60100  2.18100   2.23300   1.000 47.94641  ?  22  DC  E "H3'"  1 
ATOM   4288 H  "H2'"  . DC  E 3 6  ? 26.63500  1.68300   1.31500   1.000 45.42592  ?  22  DC  E "H2'"  1 
ATOM   4289 H  "H2''" . DC  E 3 6  ? 27.50800  0.81300   0.30300   1.000 45.42592  ?  22  DC  E "H2''" 1 
ATOM   4290 H  "H1'"  . DC  E 3 6  ? 27.17700  -1.08800  1.48000   1.000 43.81656  ?  22  DC  E "H1'"  1 
ATOM   4291 H  H41    . DC  E 3 6  ? 20.72800  -0.64300  1.63200   1.000 48.87517  ?  22  DC  E H41    1 
ATOM   4292 H  H42    . DC  E 3 6  ? 21.00300  -1.23600  0.29400   1.000 48.87517  ?  22  DC  E H42    1 
ATOM   4293 H  H5     . DC  E 3 6  ? 22.50100  0.10300   3.12000   1.000 44.36269  ?  22  DC  E H5     1 
ATOM   4294 H  H6     . DC  E 3 6  ? 24.75400  0.31000   3.39000   1.000 42.46627  ?  22  DC  E H6     1 
ATOM   4295 P  P      . DT  E 3 7  ? 30.42500  1.62700   0.31700   1.000 34.41351  ?  23  DT  E P      1 
ATOM   4296 O  OP1    . DT  E 3 7  ? 31.80000  1.08700   0.03400   1.000 34.45838  ?  23  DT  E OP1    1 
ATOM   4297 O  OP2    . DT  E 3 7  ? 30.33500  3.01500   0.73700   1.000 35.18672  -1 23  DT  E OP2    1 
ATOM   4298 O  "O5'"  . DT  E 3 7  ? 29.38900  1.41300   -0.93200  1.000 36.65150  ?  23  DT  E "O5'"  1 
ATOM   4299 C  "C5'"  . DT  E 3 7  ? 29.41300  0.16900   -1.66800  1.000 36.84661  ?  23  DT  E "C5'"  1 
ATOM   4300 C  "C4'"  . DT  E 3 7  ? 28.66300  0.31800   -2.96600  1.000 37.55514  ?  23  DT  E "C4'"  1 
ATOM   4301 O  "O4'"  . DT  E 3 7  ? 27.23100  0.39500   -2.73400  1.000 38.04807  ?  23  DT  E "O4'"  1 
ATOM   4302 C  "C3'"  . DT  E 3 7  ? 28.98900  1.58200   -3.76400  1.000 33.36147  ?  23  DT  E "C3'"  1 
ATOM   4303 O  "O3'"  . DT  E 3 7  ? 29.17800  1.14100   -5.16200  1.000 40.57908  ?  23  DT  E "O3'"  1 
ATOM   4304 C  "C2'"  . DT  E 3 7  ? 27.79000  2.50000   -3.50900  1.000 31.29652  ?  23  DT  E "C2'"  1 
ATOM   4305 C  "C1'"  . DT  E 3 7  ? 26.66800  1.50400   -3.44400  1.000 34.44373  ?  23  DT  E "C1'"  1 
ATOM   4306 N  N1     . DT  E 3 7  ? 25.37100  1.81800   -2.69500  1.000 35.04399  ?  23  DT  E N1     1 
ATOM   4307 C  C2     . DT  E 3 7  ? 24.19000  1.36900   -3.25100  1.000 38.16166  ?  23  DT  E C2     1 
ATOM   4308 O  O2     . DT  E 3 7  ? 24.11500  0.84500   -4.33600  1.000 36.34925  ?  23  DT  E O2     1 
ATOM   4309 N  N3     . DT  E 3 7  ? 23.10700  1.54900   -2.50300  1.000 37.21492  ?  23  DT  E N3     1 
ATOM   4310 C  C4     . DT  E 3 7  ? 23.02400  2.11300   -1.26800  1.000 36.99696  ?  23  DT  E C4     1 
ATOM   4311 O  O4     . DT  E 3 7  ? 21.95600  2.23600   -0.70600  1.000 34.41847  ?  23  DT  E O4     1 
ATOM   4312 C  C5     . DT  E 3 7  ? 24.28300  2.56500   -0.71000  1.000 35.16458  ?  23  DT  E C5     1 
ATOM   4313 C  C7     . DT  E 3 7  ? 24.31900  3.22500   0.66000   1.000 33.87915  ?  23  DT  E C7     1 
ATOM   4314 C  C6     . DT  E 3 7  ? 25.39200  2.36100   -1.44300  1.000 33.40479  ?  23  DT  E C6     1 
ATOM   4315 H  "H5'"  . DT  E 3 7  ? 28.99800  -0.52700  -1.13500  1.000 44.21593  ?  23  DT  E "H5'"  1 
ATOM   4316 H  "H5''" . DT  E 3 7  ? 30.33300  -0.07600  -1.85500  1.000 44.21593  ?  23  DT  E "H5''" 1 
ATOM   4317 H  "H4'"  . DT  E 3 7  ? 28.84700  -0.45600  -3.52100  1.000 45.06617  ?  23  DT  E "H4'"  1 
ATOM   4318 H  "H3'"  . DT  E 3 7  ? 29.80200  1.98900   -3.42600  1.000 40.03377  ?  23  DT  E "H3'"  1 
ATOM   4319 H  "H2'"  . DT  E 3 7  ? 27.88600  2.97100   -2.66700  1.000 37.55583  ?  23  DT  E "H2'"  1 
ATOM   4320 H  "H2''" . DT  E 3 7  ? 27.66300  3.11900   -4.24500  1.000 37.55583  ?  23  DT  E "H2''" 1 
ATOM   4321 H  "H1'"  . DT  E 3 7  ? 26.45000  1.22100   -4.34500  1.000 41.33247  ?  23  DT  E "H1'"  1 
ATOM   4322 H  H71    . DT  E 3 7  ? 23.44400  3.59000   0.86600   1.000 40.65498  ?  23  DT  E H71    1 
ATOM   4323 H  H72    . DT  E 3 7  ? 24.56000  2.56700   1.33000   1.000 40.65498  ?  23  DT  E H72    1 
ATOM   4324 H  H73    . DT  E 3 7  ? 24.97500  3.93900   0.65800   1.000 40.65498  ?  23  DT  E H73    1 
ATOM   4325 H  H6     . DT  E 3 7  ? 26.21000  2.62600   -1.09000  1.000 40.08574  ?  23  DT  E H6     1 
ATOM   4326 P  P      . DT  E 3 8  ? 29.80500  2.08200   -6.27200  1.000 38.14027  ?  24  DT  E P      1 
ATOM   4327 O  OP1    . DT  E 3 8  ? 30.62800  1.14900   -7.10500  1.000 44.87239  ?  24  DT  E OP1    1 
ATOM   4328 O  OP2    . DT  E 3 8  ? 30.40000  3.28800   -5.70900  1.000 36.10780  -1 24  DT  E OP2    1 
ATOM   4329 O  "O5'"  . DT  E 3 8  ? 28.52000  2.56900   -7.09600  1.000 34.77657  ?  24  DT  E "O5'"  1 
ATOM   4330 C  "C5'"  . DT  E 3 8  ? 27.67200  1.58400   -7.67300  1.000 37.71134  ?  24  DT  E "C5'"  1 
ATOM   4331 C  "C4'"  . DT  E 3 8  ? 26.34200  2.17100   -8.12400  1.000 36.75748  ?  24  DT  E "C4'"  1 
ATOM   4332 O  "O4'"  . DT  E 3 8  ? 25.47700  2.44700   -7.00600  1.000 34.74479  ?  24  DT  E "O4'"  1 
ATOM   4333 C  "C3'"  . DT  E 3 8  ? 26.44300  3.47500   -8.91400  1.000 36.36260  ?  24  DT  E "C3'"  1 
ATOM   4334 O  "O3'"  . DT  E 3 8  ? 26.01800  3.18700   -10.29000 1.000 40.39150  ?  24  DT  E "O3'"  1 
ATOM   4335 C  "C2'"  . DT  E 3 8  ? 25.52000  4.46300   -8.16800  1.000 30.48846  ?  24  DT  E "C2'"  1 
ATOM   4336 C  "C1'"  . DT  E 3 8  ? 24.64800  3.52700   -7.32700  1.000 34.73063  ?  24  DT  E "C1'"  1 
ATOM   4337 N  N1     . DT  E 3 8  ? 24.09900  4.01000   -6.05400  1.000 33.50495  ?  24  DT  E N1     1 
ATOM   4338 C  C2     . DT  E 3 8  ? 22.73400  3.82600   -5.81600  1.000 35.65019  ?  24  DT  E C2     1 
ATOM   4339 O  O2     . DT  E 3 8  ? 21.96000  3.40600   -6.63000  1.000 35.97539  ?  24  DT  E O2     1 
ATOM   4340 N  N3     . DT  E 3 8  ? 22.30900  4.17500   -4.60900  1.000 29.20469  ?  24  DT  E N3     1 
ATOM   4341 C  C4     . DT  E 3 8  ? 23.03900  4.68900   -3.56700  1.000 32.49323  ?  24  DT  E C4     1 
ATOM   4342 O  O4     . DT  E 3 8  ? 22.49700  5.02000   -2.47800  1.000 32.37700  ?  24  DT  E O4     1 
ATOM   4343 C  C5     . DT  E 3 8  ? 24.44700  4.86600   -3.83700  1.000 34.45066  ?  24  DT  E C5     1 
ATOM   4344 C  C7     . DT  E 3 8  ? 25.32700  5.43900   -2.78000  1.000 31.99746  ?  24  DT  E C7     1 
ATOM   4345 C  C6     . DT  E 3 8  ? 24.92400  4.49900   -5.06700  1.000 33.68116  ?  24  DT  E C6     1 
ATOM   4346 H  "H5'"  . DT  E 3 8  ? 27.50400  0.88900   -7.01700  1.000 45.25361  ?  24  DT  E "H5'"  1 
ATOM   4347 H  "H5''" . DT  E 3 8  ? 28.12000  1.19200   -8.43900  1.000 45.25361  ?  24  DT  E "H5''" 1 
ATOM   4348 H  "H4'"  . DT  E 3 8  ? 25.90300  1.51400   -8.68700  1.000 44.10898  ?  24  DT  E "H4'"  1 
ATOM   4349 H  "H3'"  . DT  E 3 8  ? 27.35700  3.80000   -8.90600  1.000 43.63512  ?  24  DT  E "H3'"  1 
ATOM   4350 H  "H2'"  . DT  E 3 8  ? 26.03700  5.05500   -7.60000  1.000 36.58616  ?  24  DT  E "H2'"  1 
ATOM   4351 H  "H2''" . DT  E 3 8  ? 24.97800  4.96800   -8.79400  1.000 36.58616  ?  24  DT  E "H2''" 1 
ATOM   4352 H  "H1'"  . DT  E 3 8  ? 23.91900  3.20500   -7.87900  1.000 41.67676  ?  24  DT  E "H1'"  1 
ATOM   4353 H  H71    . DT  E 3 8  ? 26.09900  4.86500   -2.65500  1.000 38.39695  ?  24  DT  E H71    1 
ATOM   4354 H  H72    . DT  E 3 8  ? 25.62200  6.32300   -3.04900  1.000 38.39695  ?  24  DT  E H72    1 
ATOM   4355 H  H73    . DT  E 3 8  ? 24.83400  5.50300   -1.94700  1.000 38.39695  ?  24  DT  E H73    1 
ATOM   4356 H  H6     . DT  E 3 8  ? 25.83400  4.58300   -5.24100  1.000 40.41739  ?  24  DT  E H6     1 
ATOM   4357 P  P      . DC  E 3 9  ? 26.22300  4.24100   -11.49100 1.000 37.38283  ?  25  DC  E P      1 
ATOM   4358 O  OP1    . DC  E 3 9  ? 26.22800  3.35900   -12.71100 1.000 47.87240  ?  25  DC  E OP1    1 
ATOM   4359 O  OP2    . DC  E 3 9  ? 27.36900  5.12100   -11.24300 1.000 41.49626  -1 25  DC  E OP2    1 
ATOM   4360 O  "O5'"  . DC  E 3 9  ? 24.88200  5.07700   -11.45200 1.000 37.41216  ?  25  DC  E "O5'"  1 
ATOM   4361 C  "C5'"  . DC  E 3 9  ? 23.67500  4.35200   -11.39200 1.000 41.33216  ?  25  DC  E "C5'"  1 
ATOM   4362 C  "C4'"  . DC  E 3 9  ? 22.51000  5.23900   -11.03600 1.000 43.95753  ?  25  DC  E "C4'"  1 
ATOM   4363 O  "O4'"  . DC  E 3 9  ? 22.41400  5.39000   -9.60500  1.000 41.59675  ?  25  DC  E "O4'"  1 
ATOM   4364 C  "C3'"  . DC  E 3 9  ? 22.59900  6.66900   -11.57400 1.000 44.29663  ?  25  DC  E "C3'"  1 
ATOM   4365 O  "O3'"  . DC  E 3 9  ? 21.62900  6.82200   -12.55300 1.000 61.76428  ?  25  DC  E "O3'"  1 
ATOM   4366 C  "C2'"  . DC  E 3 9  ? 22.35300  7.56800   -10.36800 1.000 41.84293  ?  25  DC  E "C2'"  1 
ATOM   4367 C  "C1'"  . DC  E 3 9  ? 21.73100  6.58900   -9.39200  1.000 43.33916  ?  25  DC  E "C1'"  1 
ATOM   4368 N  N1     . DC  E 3 9  ? 21.86400  6.93800   -8.01900  1.000 39.06419  ?  25  DC  E N1     1 
ATOM   4369 C  C2     . DC  E 3 9  ? 20.70900  6.95500   -7.21300  1.000 38.28740  ?  25  DC  E C2     1 
ATOM   4370 O  O2     . DC  E 3 9  ? 19.59600  6.65800   -7.73300  1.000 39.60614  ?  25  DC  E O2     1 
ATOM   4371 N  N3     . DC  E 3 9  ? 20.83200  7.27800   -5.90200  1.000 33.30700  ?  25  DC  E N3     1 
ATOM   4372 C  C4     . DC  E 3 9  ? 22.05400  7.56200   -5.39500  1.000 33.94869  ?  25  DC  E C4     1 
ATOM   4373 N  N4     . DC  E 3 9  ? 22.14700  7.86900   -4.06800  1.000 34.27056  ?  25  DC  E N4     1 
ATOM   4374 C  C5     . DC  E 3 9  ? 23.22200  7.56800   -6.21800  1.000 34.87638  ?  25  DC  E C5     1 
ATOM   4375 C  C6     . DC  E 3 9  ? 23.07600  7.24900   -7.52000  1.000 33.80983  ?  25  DC  E C6     1 
ATOM   4376 H  "H5'"  . DC  E 3 9  ? 23.75600  3.65500   -10.72300 1.000 49.59859  ?  25  DC  E "H5'"  1 
ATOM   4377 H  "H5''" . DC  E 3 9  ? 23.50900  3.94300   -12.25600 1.000 49.59859  ?  25  DC  E "H5''" 1 
ATOM   4378 H  "H4'"  . DC  E 3 9  ? 21.69300  4.83100   -11.36400 1.000 52.74904  ?  25  DC  E "H4'"  1 
ATOM   4379 H  "H3'"  . DC  E 3 9  ? 23.47900  6.83700   -11.94400 1.000 53.15596  ?  25  DC  E "H3'"  1 
ATOM   4380 H  "H2'"  . DC  E 3 9  ? 23.18700  7.92500   -10.02700 1.000 50.21151  ?  25  DC  E "H2'"  1 
ATOM   4381 H  "H2''" . DC  E 3 9  ? 21.73200  8.27600   -10.59000 1.000 50.21151  ?  25  DC  E "H2''" 1 
ATOM   4382 H  "H1'"  . DC  E 3 9  ? 20.79500  6.46900   -9.61100  1.000 52.00699  ?  25  DC  E "H1'"  1 
ATOM   4383 H  H41    . DC  E 3 9  ? 22.91200  8.05300   -3.72200  1.000 41.12467  ?  25  DC  E H41    1 
ATOM   4384 H  H42    . DC  E 3 9  ? 21.44000  7.87800   -3.57800  1.000 41.12467  ?  25  DC  E H42    1 
ATOM   4385 H  H5     . DC  E 3 9  ? 24.05800  7.76700   -5.86300  1.000 41.85165  ?  25  DC  E H5     1 
ATOM   4386 H  H6     . DC  E 3 9  ? 23.82200  7.22600   -8.07500  1.000 40.57180  ?  25  DC  E H6     1 
ATOM   4387 P  P      . DC  E 3 10 ? 21.71000  7.98700   -13.66000 1.000 60.17051  ?  26  DC  E P      1 
ATOM   4388 O  OP1    . DC  E 3 10 ? 21.09000  7.56000   -14.97600 1.000 58.61382  ?  26  DC  E OP1    1 
ATOM   4389 O  OP2    . DC  E 3 10 ? 23.07600  8.63200   -13.80900 1.000 55.31581  -1 26  DC  E OP2    1 
ATOM   4390 O  "O5'"  . DC  E 3 10 ? 20.73900  9.10300   -13.03000 1.000 52.16499  ?  26  DC  E "O5'"  1 
ATOM   4391 C  "C5'"  . DC  E 3 10 ? 19.31600  8.84900   -13.01900 1.000 45.90644  ?  26  DC  E "C5'"  1 
ATOM   4392 C  "C4'"  . DC  E 3 10 ? 18.67000  9.67300   -11.93600 1.000 49.34710  ?  26  DC  E "C4'"  1 
ATOM   4393 O  "O4'"  . DC  E 3 10 ? 19.30300  9.41700   -10.66900 1.000 45.78984  ?  26  DC  E "O4'"  1 
ATOM   4394 C  "C3'"  . DC  E 3 10 ? 18.79200  11.18200  -12.09900 1.000 44.90682  ?  26  DC  E "C3'"  1 
ATOM   4395 O  "O3'"  . DC  E 3 10 ? 17.72700  11.71600  -12.88000 1.000 40.76594  ?  26  DC  E "O3'"  1 
ATOM   4396 C  "C2'"  . DC  E 3 10 ? 18.69800  11.69000  -10.66500 1.000 45.30692  ?  26  DC  E "C2'"  1 
ATOM   4397 C  "C1'"  . DC  E 3 10 ? 18.89500  10.45400  -9.80400  1.000 43.48862  ?  26  DC  E "C1'"  1 
ATOM   4398 N  N1     . DC  E 3 10 ? 19.90800  10.64100  -8.73900  1.000 41.43302  ?  26  DC  E N1     1 
ATOM   4399 C  C2     . DC  E 3 10 ? 19.48200  11.14300  -7.50900  1.000 43.23677  ?  26  DC  E C2     1 
ATOM   4400 O  O2     . DC  E 3 10 ? 18.28300  11.41300  -7.35100  1.000 44.44688  ?  26  DC  E O2     1 
ATOM   4401 N  N3     . DC  E 3 10 ? 20.39300  11.33500  -6.53100  1.000 36.34368  ?  26  DC  E N3     1 
ATOM   4402 C  C4     . DC  E 3 10 ? 21.67900  11.04900  -6.72800  1.000 37.34809  ?  26  DC  E C4     1 
ATOM   4403 N  N4     . DC  E 3 10 ? 22.51000  11.25800  -5.72100  1.000 37.96473  ?  26  DC  E N4     1 
ATOM   4404 C  C5     . DC  E 3 10 ? 22.13500  10.54700  -7.97400  1.000 41.11062  ?  26  DC  E C5     1 
ATOM   4405 C  C6     . DC  E 3 10 ? 21.22500  10.37000  -8.94300  1.000 38.98054  ?  26  DC  E C6     1 
ATOM   4406 H  "H5'"  . DC  E 3 10 ? 19.15700  7.90800   -12.84800 1.000 55.08772  ?  26  DC  E "H5'"  1 
ATOM   4407 H  "H5''" . DC  E 3 10 ? 18.93700  9.09100   -13.87900 1.000 55.08772  ?  26  DC  E "H5''" 1 
ATOM   4408 H  "H4'"  . DC  E 3 10 ? 17.73100  9.43600   -11.87500 1.000 59.21652  ?  26  DC  E "H4'"  1 
ATOM   4409 H  "H3'"  . DC  E 3 10 ? 19.65100  11.41400  -12.48600 1.000 53.88819  ?  26  DC  E "H3'"  1 
ATOM   4410 H  "H2'"  . DC  E 3 10 ? 19.39700  12.33800  -10.49000 1.000 54.36831  ?  26  DC  E "H2'"  1 
ATOM   4411 H  "H2''" . DC  E 3 10 ? 17.82500  12.08000  -10.50100 1.000 54.36831  ?  26  DC  E "H2''" 1 
ATOM   4412 H  "H1'"  . DC  E 3 10 ? 18.04800  10.21200  -9.39800  1.000 52.18634  ?  26  DC  E "H1'"  1 
ATOM   4413 H  H41    . DC  E 3 10 ? 23.34800  11.08500  -5.81200  1.000 45.55768  ?  26  DC  E H41    1 
ATOM   4414 H  H42    . DC  E 3 10 ? 22.21300  11.56700  -4.97500  1.000 45.55768  ?  26  DC  E H42    1 
ATOM   4415 H  H5     . DC  E 3 10 ? 23.03200  10.34700  -8.11300  1.000 49.33274  ?  26  DC  E H5     1 
ATOM   4416 H  H6     . DC  E 3 10 ? 21.49700  10.03500  -9.76500  1.000 46.77665  ?  26  DC  E H6     1 
ATOM   4417 P  P      . DT  E 3 11 ? 17.58900  13.29900  -13.13400 1.000 45.81587  ?  27  DT  E P      1 
ATOM   4418 O  OP1    . DT  E 3 11 ? 16.82300  13.48700  -14.40100 1.000 52.70342  ?  27  DT  E OP1    1 
ATOM   4419 O  OP2    . DT  E 3 11 ? 18.96100  13.89300  -13.01400 1.000 48.15466  -1 27  DT  E OP2    1 
ATOM   4420 O  "O5'"  . DT  E 3 11 ? 16.66500  13.77600  -11.88200 1.000 45.33214  ?  27  DT  E "O5'"  1 
ATOM   4421 C  "C5'"  . DT  E 3 11 ? 15.40300  13.07500  -11.64700 1.000 45.02082  ?  27  DT  E "C5'"  1 
ATOM   4422 C  "C4'"  . DT  E 3 11 ? 14.66900  13.65900  -10.46300 1.000 43.02884  ?  27  DT  E "C4'"  1 
ATOM   4423 O  "O4'"  . DT  E 3 11 ? 15.42100  13.39400  -9.20000  1.000 40.87676  ?  27  DT  E "O4'"  1 
ATOM   4424 C  "C3'"  . DT  E 3 11 ? 14.50400  15.15900  -10.55700 1.000 41.65192  ?  27  DT  E "C3'"  1 
ATOM   4425 O  "O3'"  . DT  E 3 11 ? 13.17900  15.51800  -10.18100 1.000 45.14132  ?  27  DT  E "O3'"  1 
ATOM   4426 C  "C2'"  . DT  E 3 11 ? 15.60800  15.69700  -9.63400  1.000 44.15257  ?  27  DT  E "C2'"  1 
ATOM   4427 C  "C1'"  . DT  E 3 11 ? 15.75700  14.59600  -8.58000  1.000 35.50217  ?  27  DT  E "C1'"  1 
ATOM   4428 N  N1     . DT  E 3 11 ? 17.17400  14.45300  -7.99600  1.000 43.84469  ?  27  DT  E N1     1 
ATOM   4429 C  C2     . DT  E 3 11 ? 17.31600  14.35100  -6.62500  1.000 38.67576  ?  27  DT  E C2     1 
ATOM   4430 O  O2     . DT  E 3 11 ? 16.37100  14.36400  -5.88400  1.000 36.40659  ?  27  DT  E O2     1 
ATOM   4431 N  N3     . DT  E 3 11 ? 18.61100  14.23200  -6.16100  1.000 34.56350  ?  27  DT  E N3     1 
ATOM   4432 C  C4     . DT  E 3 11 ? 19.75700  14.23100  -6.90200  1.000 36.15064  ?  27  DT  E C4     1 
ATOM   4433 O  O4     . DT  E 3 11 ? 20.87900  14.11600  -6.39100  1.000 32.70972  ?  27  DT  E O4     1 
ATOM   4434 C  C5     . DT  E 3 11 ? 19.55800  14.36000  -8.35300  1.000 38.12435  ?  27  DT  E C5     1 
ATOM   4435 C  C7     . DT  E 3 11 ? 20.72800  14.35000  -9.25300  1.000 35.78872  ?  27  DT  E C7     1 
ATOM   4436 C  C6     . DT  E 3 11 ? 18.29600  14.46800  -8.82300  1.000 41.89689  ?  27  DT  E C6     1 
ATOM   4437 H  "H5'"  . DT  E 3 11 ? 15.58600  12.13800  -11.47700 1.000 54.02498  ?  27  DT  E "H5'"  1 
ATOM   4438 H  "H5''" . DT  E 3 11 ? 14.84800  13.15200  -12.43500 1.000 54.02498  ?  27  DT  E "H5''" 1 
ATOM   4439 H  "H4'"  . DT  E 3 11 ? 13.79300  13.24800  -10.40100 1.000 51.63460  ?  27  DT  E "H4'"  1 
ATOM   4440 H  "H3'"  . DT  E 3 11 ? 14.67300  15.44700  -11.46800 1.000 49.98230  ?  27  DT  E "H3'"  1 
ATOM   4441 H  "H2'"  . DT  E 3 11 ? 16.43400  15.81500  -10.12700 1.000 52.98308  ?  27  DT  E "H2'"  1 
ATOM   4442 H  "H2''" . DT  E 3 11 ? 15.33400  16.53000  -9.22000  1.000 52.98308  ?  27  DT  E "H2''" 1 
ATOM   4443 H  "H1'"  . DT  E 3 11 ? 15.13200  14.76400  -7.85800  1.000 42.60260  ?  27  DT  E "H1'"  1 
ATOM   4444 H  H3     . DT  E 3 11 ? 18.70700  14.16800  -5.30900  1.000 41.47620  ?  27  DT  E H3     1 
ATOM   4445 H  H71    . DT  E 3 11 ? 21.43900  14.88400  -8.86500  1.000 42.94647  ?  27  DT  E H71    1 
ATOM   4446 H  H72    . DT  E 3 11 ? 21.03700  13.43800  -9.37200  1.000 42.94647  ?  27  DT  E H72    1 
ATOM   4447 H  H73    . DT  E 3 11 ? 20.47800  14.72200  -10.11300 1.000 42.94647  ?  27  DT  E H73    1 
ATOM   4448 H  H6     . DT  E 3 11 ? 18.16900  14.54200  -9.74100  1.000 50.27627  ?  27  DT  E H6     1 
ATOM   4449 P  P      . DT  E 3 12 ? 12.75900  17.05300  -9.94300  1.000 50.37141  ?  28  DT  E P      1 
ATOM   4450 O  OP1    . DT  E 3 12 ? 11.29500  17.09700  -10.22200 1.000 60.25708  ?  28  DT  E OP1    1 
ATOM   4451 O  OP2    . DT  E 3 12 ? 13.65900  18.05300  -10.56200 1.000 41.25493  -1 28  DT  E OP2    1 
ATOM   4452 O  "O5'"  . DT  E 3 12 ? 12.93500  17.20500  -8.36500  1.000 49.41981  ?  28  DT  E "O5'"  1 
ATOM   4453 C  "C5'"  . DT  E 3 12 ? 12.26200  16.35100  -7.49300  1.000 43.18320  ?  28  DT  E "C5'"  1 
ATOM   4454 C  "C4'"  . DT  E 3 12 ? 12.46200  16.84000  -6.07700  1.000 46.89169  ?  28  DT  E "C4'"  1 
ATOM   4455 O  "O4'"  . DT  E 3 12 ? 13.83900  16.58800  -5.68700  1.000 45.46057  ?  28  DT  E "O4'"  1 
ATOM   4456 C  "C3'"  . DT  E 3 12 ? 12.24100  18.34400  -5.87400  1.000 44.41735  ?  28  DT  E "C3'"  1 
ATOM   4457 O  "O3'"  . DT  E 3 12 ? 11.44300  18.53200  -4.70800  1.000 53.52199  ?  28  DT  E "O3'"  1 
ATOM   4458 C  "C2'"  . DT  E 3 12 ? 13.66000  18.90500  -5.76900  1.000 43.03588  ?  28  DT  E "C2'"  1 
ATOM   4459 C  "C1'"  . DT  E 3 12 ? 14.40500  17.75600  -5.15000  1.000 42.98337  ?  28  DT  E "C1'"  1 
ATOM   4460 N  N1     . DT  E 3 12 ? 15.90200  17.74300  -5.39200  1.000 42.51270  ?  28  DT  E N1     1 
ATOM   4461 C  C2     . DT  E 3 12 ? 16.73400  17.58800  -4.32000  1.000 37.88753  ?  28  DT  E C2     1 
ATOM   4462 O  O2     . DT  E 3 12 ? 16.33100  17.45600  -3.23900  1.000 39.91262  ?  28  DT  E O2     1 
ATOM   4463 N  N3     . DT  E 3 12 ? 18.08500  17.59400  -4.59900  1.000 36.53708  ?  28  DT  E N3     1 
ATOM   4464 C  C4     . DT  E 3 12 ? 18.66400  17.74000  -5.81300  1.000 34.88724  ?  28  DT  E C4     1 
ATOM   4465 O  O4     . DT  E 3 12 ? 19.90000  17.75300  -5.95100  1.000 34.72866  ?  28  DT  E O4     1 
ATOM   4466 C  C5     . DT  E 3 12 ? 17.72800  17.90400  -6.91600  1.000 36.23523  ?  28  DT  E C5     1 
ATOM   4467 C  C7     . DT  E 3 12 ? 18.23400  18.05900  -8.33900  1.000 41.91615  ?  28  DT  E C7     1 
ATOM   4468 C  C6     . DT  E 3 12 ? 16.41200  17.90200  -6.64800  1.000 39.62370  ?  28  DT  E C6     1 
ATOM   4469 H  "H5'"  . DT  E 3 12 ? 12.61700  15.45200  -7.58000  1.000 51.81983  ?  28  DT  E "H5'"  1 
ATOM   4470 H  "H5''" . DT  E 3 12 ? 11.31600  16.34900  -7.70600  1.000 51.81983  ?  28  DT  E "H5''" 1 
ATOM   4471 H  "H4'"  . DT  E 3 12 ? 11.87000  16.35000  -5.48500  1.000 56.27003  ?  28  DT  E "H4'"  1 
ATOM   4472 H  "H3'"  . DT  E 3 12 ? 11.79200  18.71900  -6.64800  1.000 53.30082  ?  28  DT  E "H3'"  1 
ATOM   4473 H  "H2'"  . DT  E 3 12 ? 14.01300  19.11500  -6.64700  1.000 51.64306  ?  28  DT  E "H2'"  1 
ATOM   4474 H  "H2''" . DT  E 3 12 ? 13.68200  19.68300  -5.19000  1.000 51.64306  ?  28  DT  E "H2''" 1 
ATOM   4475 H  "H1'"  . DT  E 3 12 ? 14.24500  17.76500  -4.19400  1.000 51.58004  ?  28  DT  E "H1'"  1 
ATOM   4476 H  H3     . DT  E 3 12 ? 18.61600  17.50400  -3.92900  1.000 43.84450  ?  28  DT  E H3     1 
ATOM   4477 H  H71    . DT  E 3 12 ? 17.87600  17.34500  -8.88900  1.000 50.29938  ?  28  DT  E H71    1 
ATOM   4478 H  H72    . DT  E 3 12 ? 17.94600  18.91500  -8.69300  1.000 50.29938  ?  28  DT  E H72    1 
ATOM   4479 H  H73    . DT  E 3 12 ? 19.20300  18.01600  -8.34400  1.000 50.29938  ?  28  DT  E H73    1 
ATOM   4480 H  H6     . DT  E 3 12 ? 15.81700  17.99700  -7.35700  1.000 47.54844  ?  28  DT  E H6     1 
ATOM   4481 P  P      . DT  E 3 13 ? 10.99900  19.98700  -4.17600  1.000 54.35418  ?  29  DT  E P      1 
ATOM   4482 O  OP1    . DT  E 3 13 ? 9.65200   19.72900  -3.64000  1.000 59.27273  ?  29  DT  E OP1    1 
ATOM   4483 O  OP2    . DT  E 3 13 ? 11.26300  21.10900  -5.10100  1.000 52.26237  -1 29  DT  E OP2    1 
ATOM   4484 O  "O5'"  . DT  E 3 13 ? 12.00100  20.20100  -2.92800  1.000 55.04974  ?  29  DT  E "O5'"  1 
ATOM   4485 C  "C5'"  . DT  E 3 13 ? 11.99100  19.28300  -1.87100  1.000 52.19572  ?  29  DT  E "C5'"  1 
ATOM   4486 C  "C4'"  . DT  E 3 13 ? 13.06600  19.61100  -0.85600  1.000 49.29596  ?  29  DT  E "C4'"  1 
ATOM   4487 O  "O4'"  . DT  E 3 13 ? 14.37900  19.50800  -1.44900  1.000 41.35433  ?  29  DT  E "O4'"  1 
ATOM   4488 C  "C3'"  . DT  E 3 13 ? 12.99300  21.01500  -0.26000  1.000 44.86557  ?  29  DT  E "C3'"  1 
ATOM   4489 O  "O3'"  . DT  E 3 13 ? 12.99400  20.86900  1.14500   1.000 55.23483  ?  29  DT  E "O3'"  1 
ATOM   4490 C  "C2'"  . DT  E 3 13 ? 14.23200  21.74600  -0.78700  1.000 42.18488  ?  29  DT  E "C2'"  1 
ATOM   4491 C  "C1'"  . DT  E 3 13 ? 15.19100  20.59700  -1.00600  1.000 41.27457  ?  29  DT  E "C1'"  1 
ATOM   4492 N  N1     . DT  E 3 13 ? 16.25100  20.82500  -2.04800  1.000 43.82282  ?  29  DT  E N1     1 
ATOM   4493 C  C2     . DT  E 3 13 ? 17.56100  20.68700  -1.66600  1.000 39.80055  ?  29  DT  E C2     1 
ATOM   4494 O  O2     . DT  E 3 13 ? 17.89000  20.44900  -0.52300  1.000 40.54695  ?  29  DT  E O2     1 
ATOM   4495 N  N3     . DT  E 3 13 ? 18.46400  20.85200  -2.65800  1.000 35.83092  ?  29  DT  E N3     1 
ATOM   4496 C  C4     . DT  E 3 13 ? 18.19200  21.12700  -3.99800  1.000 42.15686  ?  29  DT  E C4     1 
ATOM   4497 O  O4     . DT  E 3 13 ? 19.08900  21.26100  -4.82400  1.000 40.52391  ?  29  DT  E O4     1 
ATOM   4498 C  C5     . DT  E 3 13 ? 16.76200  21.26800  -4.34100  1.000 38.90250  ?  29  DT  E C5     1 
ATOM   4499 C  C7     . DT  E 3 13 ? 16.33300  21.57700  -5.75700  1.000 45.83517  ?  29  DT  E C7     1 
ATOM   4500 C  C6     . DT  E 3 13 ? 15.87900  21.07600  -3.37000  1.000 38.75948  ?  29  DT  E C6     1 
ATOM   4501 H  "H5'"  . DT  E 3 13 ? 12.14600  18.39200  -2.22200  1.000 62.63487  ?  29  DT  E "H5'"  1 
ATOM   4502 H  "H5''" . DT  E 3 13 ? 11.12400  19.30800  -1.43600  1.000 62.63487  ?  29  DT  E "H5''" 1 
ATOM   4503 H  "H4'"  . DT  E 3 13 ? 13.00700  18.96900  -0.13200  1.000 59.15516  ?  29  DT  E "H4'"  1 
ATOM   4504 H  "H3'"  . DT  E 3 13 ? 12.18500  21.46400  -0.55400  1.000 53.83868  ?  29  DT  E "H3'"  1 
ATOM   4505 H  "H2'"  . DT  E 3 13 ? 14.03700  22.19900  -1.62200  1.000 50.62185  ?  29  DT  E "H2'"  1 
ATOM   4506 H  "H2''" . DT  E 3 13 ? 14.57800  22.36500  -0.12500  1.000 50.62185  ?  29  DT  E "H2''" 1 
ATOM   4507 H  "H1'"  . DT  E 3 13 ? 15.60900  20.36300  -0.16300  1.000 49.52949  ?  29  DT  E "H1'"  1 
ATOM   4508 H  H3     . DT  E 3 13 ? 19.29100  20.78100  -2.44100  1.000 42.99710  ?  29  DT  E H3     1 
ATOM   4509 H  H71    . DT  E 3 13 ? 15.76100  20.86500  -6.08400  1.000 55.00220  ?  29  DT  E H71    1 
ATOM   4510 H  H72    . DT  E 3 13 ? 15.84600  22.41600  -5.77100  1.000 55.00220  ?  29  DT  E H72    1 
ATOM   4511 H  H73    . DT  E 3 13 ? 17.11600  21.64900  -6.32400  1.000 55.00220  ?  29  DT  E H73    1 
ATOM   4512 H  H6     . DT  E 3 13 ? 14.97400  21.15900  -3.56900  1.000 46.51137  ?  29  DT  E H6     1 
ATOM   4513 P  P      . DT  E 3 14 ? 12.77500  22.13900  2.08800   1.000 55.48277  ?  30  DT  E P      1 
ATOM   4514 O  OP1    . DT  E 3 14 ? 12.01300  21.54700  3.20600   1.000 60.50298  ?  30  DT  E OP1    1 
ATOM   4515 O  OP2    . DT  E 3 14 ? 12.29400  23.28100  1.26300   1.000 58.28825  -1 30  DT  E OP2    1 
ATOM   4516 O  "O5'"  . DT  E 3 14 ? 14.26000  22.52300  2.51600   1.000 51.11982  ?  30  DT  E "O5'"  1 
ATOM   4517 C  "C5'"  . DT  E 3 14 ? 15.06000  21.52400  3.02100   1.000 51.01549  ?  30  DT  E "C5'"  1 
ATOM   4518 C  "C4'"  . DT  E 3 14 ? 16.44900  22.03300  3.31500   1.000 51.79420  ?  30  DT  E "C4'"  1 
ATOM   4519 O  "O4'"  . DT  E 3 14 ? 17.18000  22.17500  2.09000   1.000 45.22313  ?  30  DT  E "O4'"  1 
ATOM   4520 C  "C3'"  . DT  E 3 14 ? 16.52900  23.39800  4.01000   1.000 51.35214  ?  30  DT  E "C3'"  1 
ATOM   4521 O  "O3'"  . DT  E 3 14 ? 17.29300  23.20000  5.20300   1.000 59.49384  ?  30  DT  E "O3'"  1 
ATOM   4522 C  "C2'"  . DT  E 3 14 ? 17.18100  24.32700  2.95700   1.000 49.82706  ?  30  DT  E "C2'"  1 
ATOM   4523 C  "C1'"  . DT  E 3 14 ? 17.95900  23.34400  2.10600   1.000 44.40912  ?  30  DT  E "C1'"  1 
ATOM   4524 N  N1     . DT  E 3 14 ? 18.19500  23.69000  0.68900   1.000 42.64406  ?  30  DT  E N1     1 
ATOM   4525 C  C2     . DT  E 3 14 ? 19.46900  23.68000  0.22000   1.000 43.00739  ?  30  DT  E C2     1 
ATOM   4526 O  O2     . DT  E 3 14 ? 20.41900  23.48100  0.92300   1.000 39.62346  ?  30  DT  E O2     1 
ATOM   4527 N  N3     . DT  E 3 14 ? 19.59800  23.95500  -1.12600  1.000 46.97814  ?  30  DT  E N3     1 
ATOM   4528 C  C4     . DT  E 3 14 ? 18.58100  24.19200  -2.03200  1.000 40.24166  ?  30  DT  E C4     1 
ATOM   4529 O  O4     . DT  E 3 14 ? 18.80800  24.43400  -3.23200  1.000 47.34168  ?  30  DT  E O4     1 
ATOM   4530 C  C5     . DT  E 3 14 ? 17.25700  24.18300  -1.47100  1.000 44.98289  ?  30  DT  E C5     1 
ATOM   4531 C  C7     . DT  E 3 14 ? 16.06100  24.43500  -2.34400  1.000 44.91290  ?  30  DT  E C7     1 
ATOM   4532 C  C6     . DT  E 3 14 ? 17.12500  23.90300  -0.15600  1.000 45.41129  ?  30  DT  E C6     1 
ATOM   4533 H  "H5'"  . DT  E 3 14 ? 15.11600  20.80400  2.37400   1.000 61.21858  ?  30  DT  E "H5'"  1 
ATOM   4534 H  "H5''" . DT  E 3 14 ? 14.66600  21.18500  3.84000   1.000 61.21858  ?  30  DT  E "H5''" 1 
ATOM   4535 H  "H4'"  . DT  E 3 14 ? 16.90300  21.38000  3.87000   1.000 62.15304  ?  30  DT  E "H4'"  1 
ATOM   4536 H  "H3'"  . DT  E 3 14 ? 15.63800  23.71300  4.23000   1.000 61.62257  ?  30  DT  E "H3'"  1 
ATOM   4537 H  "H2'"  . DT  E 3 14 ? 16.50400  24.78000  2.43000   1.000 59.79247  ?  30  DT  E "H2'"  1 
ATOM   4538 H  "H2''" . DT  E 3 14 ? 17.77700  24.96400  3.38100   1.000 59.79247  ?  30  DT  E "H2''" 1 
ATOM   4539 H  "H1'"  . DT  E 3 14 ? 18.80700  23.15400  2.53600   1.000 53.29095  ?  30  DT  E "H1'"  1 
ATOM   4540 H  H3     . DT  E 3 14 ? 20.39900  23.96900  -1.43800  1.000 56.37376  ?  30  DT  E H3     1 
ATOM   4541 H  H71    . DT  E 3 14 ? 15.27100  24.05700  -1.92800  1.000 53.89549  ?  30  DT  E H71    1 
ATOM   4542 H  H72    . DT  E 3 14 ? 15.94000  25.39100  -2.45800  1.000 53.89549  ?  30  DT  E H72    1 
ATOM   4543 H  H73    . DT  E 3 14 ? 16.20000  24.02200  -3.21000  1.000 53.89549  ?  30  DT  E H73    1 
ATOM   4544 H  H6     . DT  E 3 14 ? 16.26800  23.88100  0.20500   1.000 54.49355  ?  30  DT  E H6     1 
ATOM   4545 P  P      . DA  E 3 15 ? 17.63600  24.40600  6.21000   1.000 58.35499  ?  31  DA  E P      1 
ATOM   4546 O  OP1    . DA  E 3 15 ? 17.77000  23.73400  7.50500   1.000 63.36644  ?  31  DA  E OP1    1 
ATOM   4547 O  OP2    . DA  E 3 15 ? 16.78400  25.58700  5.92800   1.000 58.31291  -1 31  DA  E OP2    1 
ATOM   4548 O  "O5'"  . DA  E 3 15 ? 19.11800  24.83600  5.80600   1.000 54.07419  ?  31  DA  E "O5'"  1 
ATOM   4549 C  "C5'"  . DA  E 3 15 ? 20.14600  23.85700  5.79500   1.000 56.23745  ?  31  DA  E "C5'"  1 
ATOM   4550 C  "C4'"  . DA  E 3 15 ? 21.44900  24.48300  5.34100   1.000 56.77745  ?  31  DA  E "C4'"  1 
ATOM   4551 O  "O4'"  . DA  E 3 15 ? 21.38000  24.74800  3.92400   1.000 58.25608  ?  31  DA  E "O4'"  1 
ATOM   4552 C  "C3'"  . DA  E 3 15 ? 21.78300  25.81800  5.99900   1.000 60.25276  ?  31  DA  E "C3'"  1 
ATOM   4553 O  "O3'"  . DA  E 3 15 ? 23.13800  25.80600  6.36500   1.000 69.58123  ?  31  DA  E "O3'"  1 
ATOM   4554 C  "C2'"  . DA  E 3 15 ? 21.45700  26.85800  4.91800   1.000 60.66874  ?  31  DA  E "C2'"  1 
ATOM   4555 C  "C1'"  . DA  E 3 15 ? 21.77100  26.09000  3.64500   1.000 58.86228  ?  31  DA  E "C1'"  1 
ATOM   4556 N  N9     . DA  E 3 15 ? 21.06700  26.50600  2.42600   1.000 55.49042  ?  31  DA  E N9     1 
ATOM   4557 C  C8     . DA  E 3 15 ? 19.73600  26.69800  2.27800   1.000 51.50247  ?  31  DA  E C8     1 
ATOM   4558 N  N7     . DA  E 3 15 ? 19.38100  27.03100  1.05100   1.000 52.12065  ?  31  DA  E N7     1 
ATOM   4559 C  C5     . DA  E 3 15 ? 20.54700  27.01900  0.34900   1.000 50.24520  ?  31  DA  E C5     1 
ATOM   4560 C  C6     . DA  E 3 15 ? 20.82200  27.26500  -0.99600  1.000 53.29893  ?  31  DA  E C6     1 
ATOM   4561 N  N6     . DA  E 3 15 ? 19.88700  27.59600  -1.88500  1.000 59.04466  ?  31  DA  E N6     1 
ATOM   4562 N  N1     . DA  E 3 15 ? 22.08900  27.16300  -1.40200  1.000 53.13058  ?  31  DA  E N1     1 
ATOM   4563 C  C2     . DA  E 3 15 ? 23.02400  26.85300  -0.51200  1.000 56.37876  ?  31  DA  E C2     1 
ATOM   4564 N  N3     . DA  E 3 15 ? 22.89000  26.59800  0.80100   1.000 52.77589  ?  31  DA  E N3     1 
ATOM   4565 C  C4     . DA  E 3 15 ? 21.60600  26.69000  1.16300   1.000 52.47685  ?  31  DA  E C4     1 
ATOM   4566 H  "H5'"  . DA  E 3 15 ? 19.90300  23.14200  5.18600   1.000 67.48493  ?  31  DA  E "H5'"  1 
ATOM   4567 H  "H5''" . DA  E 3 15 ? 20.25600  23.49600  6.68800   1.000 67.48493  ?  31  DA  E "H5''" 1 
ATOM   4568 H  "H4'"  . DA  E 3 15 ? 22.17300  23.86000  5.51000   1.000 68.13294  ?  31  DA  E "H4'"  1 
ATOM   4569 H  "H3'"  . DA  E 3 15 ? 21.22400  25.95700  6.77900   1.000 72.30331  ?  31  DA  E "H3'"  1 
ATOM   4570 H  "H2'"  . DA  E 3 15 ? 20.52000  27.10800  4.95000   1.000 72.80249  ?  31  DA  E "H2'"  1 
ATOM   4571 H  "H2''" . DA  E 3 15 ? 22.02900  27.63700  5.00300   1.000 72.80249  ?  31  DA  E "H2''" 1 
ATOM   4572 H  "H1'"  . DA  E 3 15 ? 22.72700  26.11600  3.48500   1.000 70.63474  ?  31  DA  E "H1'"  1 
ATOM   4573 H  H8     . DA  E 3 15 ? 19.13200  26.63600  2.98300   1.000 61.80296  ?  31  DA  E H8     1 
ATOM   4574 H  H61    . DA  E 3 15 ? 20.10500  27.74000  -2.70500  1.000 70.85359  ?  31  DA  E H61    1 
ATOM   4575 H  H62    . DA  E 3 15 ? 19.06600  27.66600  -1.63900  1.000 70.85359  ?  31  DA  E H62    1 
ATOM   4576 H  H2     . DA  E 3 15 ? 23.89100  26.80100  -0.84400  1.000 67.65452  ?  31  DA  E H2     1 
ATOM   4577 P  P      . DT  E 3 16 ? 23.76100  26.94900  7.29800   1.000 74.25354  ?  32  DT  E P      1 
ATOM   4578 O  OP1    . DT  E 3 16 ? 24.62700  26.22900  8.26200   1.000 77.11272  ?  32  DT  E OP1    1 
ATOM   4579 O  OP2    . DT  E 3 16 ? 22.69300  27.82500  7.82700   1.000 70.50588  -1 32  DT  E OP2    1 
ATOM   4580 O  "O5'"  . DT  E 3 16 ? 24.66700  27.77600  6.27200   1.000 69.85117  ?  32  DT  E "O5'"  1 
ATOM   4581 C  "C5'"  . DT  E 3 16 ? 25.77400  27.13200  5.66100   1.000 72.00001  ?  32  DT  E "C5'"  1 
ATOM   4582 C  "C4'"  . DT  E 3 16 ? 26.23600  27.88300  4.42700   1.000 71.84717  ?  32  DT  E "C4'"  1 
ATOM   4583 O  "O4'"  . DT  E 3 16 ? 25.14100  27.99900  3.49500   1.000 74.97016  ?  32  DT  E "O4'"  1 
ATOM   4584 C  "C3'"  . DT  E 3 16 ? 26.70900  29.31200  4.69300   1.000 76.16697  ?  32  DT  E "C3'"  1 
ATOM   4585 O  "O3'"  . DT  E 3 16 ? 28.12500  29.40300  4.52800   1.000 80.13033  ?  32  DT  E "O3'"  1 
ATOM   4586 C  "C2'"  . DT  E 3 16 ? 25.94200  30.18000  3.68000   1.000 76.42549  ?  32  DT  E "C2'"  1 
ATOM   4587 C  "C1'"  . DT  E 3 16 ? 25.35600  29.14900  2.71400   1.000 71.56184  ?  32  DT  E "C1'"  1 
ATOM   4588 N  N1     . DT  E 3 16 ? 24.07000  29.56600  2.06700   1.000 64.08772  ?  32  DT  E N1     1 
ATOM   4589 C  C2     . DT  E 3 16 ? 24.06600  29.81100  0.72800   1.000 62.76889  ?  32  DT  E C2     1 
ATOM   4590 O  O2     . DT  E 3 16 ? 25.06300  29.71300  0.04000   1.000 60.96174  ?  32  DT  E O2     1 
ATOM   4591 N  N3     . DT  E 3 16 ? 22.84600  30.19200  0.22000   1.000 64.02425  ?  32  DT  E N3     1 
ATOM   4592 C  C4     . DT  E 3 16 ? 21.66800  30.32800  0.91900   1.000 61.57391  ?  32  DT  E C4     1 
ATOM   4593 O  O4     . DT  E 3 16 ? 20.61800  30.66300  0.40200   1.000 63.81948  ?  32  DT  E O4     1 
ATOM   4594 C  C5     . DT  E 3 16 ? 21.74800  30.05400  2.30800   1.000 62.91484  ?  32  DT  E C5     1 
ATOM   4595 C  C7     . DT  E 3 16 ? 20.51700  30.17400  3.13800   1.000 63.62863  ?  32  DT  E C7     1 
ATOM   4596 C  C6     . DT  E 3 16 ? 22.93000  29.69000  2.82100   1.000 63.40542  ?  32  DT  E C6     1 
ATOM   4597 H  "H5'"  . DT  E 3 16 ? 25.51700  26.23200  5.40700   1.000 86.40001  ?  32  DT  E "H5'"  1 
ATOM   4598 H  "H5''" . DT  E 3 16 ? 26.50500  27.08600  6.29700   1.000 86.40001  ?  32  DT  E "H5''" 1 
ATOM   4599 H  "H4'"  . DT  E 3 16 ? 26.95400  27.38700  4.00700   1.000 86.21661  ?  32  DT  E "H4'"  1 
ATOM   4600 H  "H3'"  . DT  E 3 16 ? 26.46700  29.57300  5.59500   1.000 91.40036  ?  32  DT  E "H3'"  1 
ATOM   4601 H  "HO3'" . DT  E 3 16 ? 28.60800  29.64400  5.17200   1.000 96.15640  ?  32  DT  E "HO3'" 1 
ATOM   4602 H  "H2'"  . DT  E 3 16 ? 25.23500  30.67700  4.12100   1.000 91.71059  ?  32  DT  E "H2'"  1 
ATOM   4603 H  "H2''" . DT  E 3 16 ? 26.54700  30.77900  3.21600   1.000 91.71059  ?  32  DT  E "H2''" 1 
ATOM   4604 H  "H1'"  . DT  E 3 16 ? 26.01000  28.94900  2.02700   1.000 85.87420  ?  32  DT  E "H1'"  1 
ATOM   4605 H  H3     . DT  E 3 16 ? 22.81400  30.35200  -0.62400  1.000 76.82910  ?  32  DT  E H3     1 
ATOM   4606 H  H71    . DT  E 3 16 ? 20.43900  29.39800  3.71400   1.000 76.35436  ?  32  DT  E H71    1 
ATOM   4607 H  H72    . DT  E 3 16 ? 20.57100  30.97600  3.68200   1.000 76.35436  ?  32  DT  E H72    1 
ATOM   4608 H  H73    . DT  E 3 16 ? 19.74000  30.22700  2.56000   1.000 76.35436  ?  32  DT  E H73    1 
ATOM   4609 H  H6     . DT  E 3 16 ? 22.97900  29.50500  3.73100   1.000 76.08651  ?  32  DT  E H6     1 
ATOM   4610 O  "O5'"  . DT  F 3 1  ? 17.47800  -14.63100 29.26300  1.000 92.90858  ?  17  DT  F "O5'"  1 
ATOM   4611 C  "C5'"  . DT  F 3 1  ? 18.25400  -15.62200 28.59500  1.000 91.24861  ?  17  DT  F "C5'"  1 
ATOM   4612 C  "C4'"  . DT  F 3 1  ? 18.33100  -15.34800 27.09200  1.000 91.35747  ?  17  DT  F "C4'"  1 
ATOM   4613 O  "O4'"  . DT  F 3 1  ? 17.09700  -15.77600 26.47200  1.000 85.76840  ?  17  DT  F "O4'"  1 
ATOM   4614 C  "C3'"  . DT  F 3 1  ? 18.53500  -13.88100 26.73800  1.000 96.95793  ?  17  DT  F "C3'"  1 
ATOM   4615 O  "O3'"  . DT  F 3 1  ? 19.75600  -13.68000 26.01300  1.000 106.02576 ?  17  DT  F "O3'"  1 
ATOM   4616 C  "C2'"  . DT  F 3 1  ? 17.32500  -13.49000 25.90100  1.000 97.48328  ?  17  DT  F "C2'"  1 
ATOM   4617 C  "C1'"  . DT  F 3 1  ? 16.61600  -14.79800 25.58800  1.000 88.91373  ?  17  DT  F "C1'"  1 
ATOM   4618 N  N1     . DT  F 3 1  ? 15.15800  -14.70700 25.78000  1.000 80.01246  ?  17  DT  F N1     1 
ATOM   4619 C  C2     . DT  F 3 1  ? 14.32200  -14.63300 24.69500  1.000 80.48534  ?  17  DT  F C2     1 
ATOM   4620 O  O2     . DT  F 3 1  ? 14.71600  -14.64400 23.54100  1.000 81.42478  ?  17  DT  F O2     1 
ATOM   4621 N  N3     . DT  F 3 1  ? 12.99600  -14.54400 25.01100  1.000 77.69639  ?  17  DT  F N3     1 
ATOM   4622 C  C4     . DT  F 3 1  ? 12.44000  -14.51300 26.27900  1.000 78.27771  ?  17  DT  F C4     1 
ATOM   4623 O  O4     . DT  F 3 1  ? 11.22400  -14.43800 26.46500  1.000 80.23468  ?  17  DT  F O4     1 
ATOM   4624 C  C5     . DT  F 3 1  ? 13.39000  -14.58700 27.36700  1.000 78.44689  ?  17  DT  F C5     1 
ATOM   4625 C  C7     . DT  F 3 1  ? 12.93000  -14.57600 28.78700  1.000 78.98898  ?  17  DT  F C7     1 
ATOM   4626 C  C6     . DT  F 3 1  ? 14.68000  -14.67400 27.06500  1.000 79.60063  ?  17  DT  F C6     1 
ATOM   4627 H  "H5'"  . DT  F 3 1  ? 17.85000  -16.49200 28.73900  1.000 109.49833 ?  17  DT  F "H5'"  1 
ATOM   4628 H  "H5''" . DT  F 3 1  ? 19.15100  -15.62400 28.96400  1.000 109.49833 ?  17  DT  F "H5''" 1 
ATOM   4629 H  "H4'"  . DT  F 3 1  ? 19.06300  -15.86300 26.71800  1.000 109.62896 ?  17  DT  F "H4'"  1 
ATOM   4630 H  "H3'"  . DT  F 3 1  ? 18.55100  -13.35100 27.55000  1.000 116.34952 ?  17  DT  F "H3'"  1 
ATOM   4631 H  "H2'"  . DT  F 3 1  ? 16.74700  -12.91100 26.41300  1.000 116.97994 ?  17  DT  F "H2'"  1 
ATOM   4632 H  "H2''" . DT  F 3 1  ? 17.60700  -13.05600 25.08300  1.000 116.97994 ?  17  DT  F "H2''" 1 
ATOM   4633 H  "H1'"  . DT  F 3 1  ? 16.80900  -15.06300 24.67500  1.000 106.69648 ?  17  DT  F "H1'"  1 
ATOM   4634 H  H3     . DT  F 3 1  ? 12.44800  -14.50000 24.35300  1.000 93.23567  ?  17  DT  F H3     1 
ATOM   4635 H  H71    . DT  F 3 1  ? 11.96100  -14.54600 28.81300  1.000 94.78677  ?  17  DT  F H71    1 
ATOM   4636 H  H72    . DT  F 3 1  ? 13.24100  -15.37900 29.23400  1.000 94.78677  ?  17  DT  F H72    1 
ATOM   4637 H  H73    . DT  F 3 1  ? 13.29000  -13.79600 29.23700  1.000 94.78677  ?  17  DT  F H73    1 
ATOM   4638 H  H6     . DT  F 3 1  ? 15.29200  -14.72700 27.76300  1.000 95.52075  ?  17  DT  F H6     1 
ATOM   4639 H  "HO5'" . DT  F 3 1  ? 17.36400  -14.67700 30.09400  1.000 111.49029 ?  17  DT  F "HO5'" 1 
ATOM   4640 P  P      . DC  F 3 2  ? 20.25700  -12.18400 25.69600  1.000 107.98350 ?  18  DC  F P      1 
ATOM   4641 O  OP1    . DC  F 3 2  ? 21.70100  -12.25600 25.37800  1.000 106.57023 ?  18  DC  F OP1    1 
ATOM   4642 O  OP2    . DC  F 3 2  ? 19.76900  -11.31900 26.80600  1.000 102.94003 -1 18  DC  F OP2    1 
ATOM   4643 O  "O5'"  . DC  F 3 2  ? 19.46600  -11.78400 24.35200  1.000 109.41836 ?  18  DC  F "O5'"  1 
ATOM   4644 C  "C5'"  . DC  F 3 2  ? 19.50300  -12.64300 23.17800  1.000 100.82734 ?  18  DC  F "C5'"  1 
ATOM   4645 C  "C4'"  . DC  F 3 2  ? 18.65800  -12.05000 22.04900  1.000 98.96479  ?  18  DC  F "C4'"  1 
ATOM   4646 O  "O4'"  . DC  F 3 2  ? 17.24500  -12.28800 22.32300  1.000 94.97985  ?  18  DC  F "O4'"  1 
ATOM   4647 C  "C3'"  . DC  F 3 2  ? 18.82800  -10.53900 21.87400  1.000 98.41940  ?  18  DC  F "C3'"  1 
ATOM   4648 O  "O3'"  . DC  F 3 2  ? 19.01200  -10.19000 20.49000  1.000 105.01454 ?  18  DC  F "O3'"  1 
ATOM   4649 C  "C2'"  . DC  F 3 2  ? 17.54900  -9.94300  22.47200  1.000 92.38897  ?  18  DC  F "C2'"  1 
ATOM   4650 C  "C1'"  . DC  F 3 2  ? 16.52000  -11.06700 22.32300  1.000 90.88637  ?  18  DC  F "C1'"  1 
ATOM   4651 N  N1     . DC  F 3 2  ? 15.48400  -11.11600 23.44000  1.000 83.90690  ?  18  DC  F N1     1 
ATOM   4652 C  C2     . DC  F 3 2  ? 14.11500  -11.16900 23.13100  1.000 80.33008  ?  18  DC  F C2     1 
ATOM   4653 O  O2     . DC  F 3 2  ? 13.76100  -11.16200 21.95200  1.000 77.66126  ?  18  DC  F O2     1 
ATOM   4654 N  N3     . DC  F 3 2  ? 13.20300  -11.21000 24.15000  1.000 80.39361  ?  18  DC  F N3     1 
ATOM   4655 C  C4     . DC  F 3 2  ? 13.61800  -11.21000 25.42100  1.000 80.99344  ?  18  DC  F C4     1 
ATOM   4656 N  N4     . DC  F 3 2  ? 12.69200  -11.25900 26.38800  1.000 79.72890  ?  18  DC  F N4     1 
ATOM   4657 C  C5     . DC  F 3 2  ? 15.00400  -11.15600 25.75200  1.000 83.56024  ?  18  DC  F C5     1 
ATOM   4658 C  C6     . DC  F 3 2  ? 15.89000  -11.10300 24.74100  1.000 86.55648  ?  18  DC  F C6     1 
ATOM   4659 H  "H5'"  . DC  F 3 2  ? 19.15600  -13.51800 23.41100  1.000 120.99281 ?  18  DC  F "H5'"  1 
ATOM   4660 H  "H5''" . DC  F 3 2  ? 20.42100  -12.73300 22.87700  1.000 120.99281 ?  18  DC  F "H5''" 1 
ATOM   4661 H  "H4'"  . DC  F 3 2  ? 18.89400  -12.49000 21.21700  1.000 118.75775 ?  18  DC  F "H4'"  1 
ATOM   4662 H  "H3'"  . DC  F 3 2  ? 19.59400  -10.23900 22.38700  1.000 118.10328 ?  18  DC  F "H3'"  1 
ATOM   4663 H  "H2'"  . DC  F 3 2  ? 17.68300  -9.72100  23.40600  1.000 110.86677 ?  18  DC  F "H2'"  1 
ATOM   4664 H  "H2''" . DC  F 3 2  ? 17.27200  -9.16000  21.97100  1.000 110.86677 ?  18  DC  F "H2''" 1 
ATOM   4665 H  "H1'"  . DC  F 3 2  ? 16.06600  -10.96900 21.47200  1.000 109.06365 ?  18  DC  F "H1'"  1 
ATOM   4666 H  H41    . DC  F 3 2  ? 12.93200  -11.26000 27.21400  1.000 95.67468  ?  18  DC  F H41    1 
ATOM   4667 H  H42    . DC  F 3 2  ? 11.85700  -11.28900 26.18300  1.000 95.67468  ?  18  DC  F H42    1 
ATOM   4668 H  H5     . DC  F 3 2  ? 15.28600  -11.15400 26.63800  1.000 100.27229 ?  18  DC  F H5     1 
ATOM   4669 H  H6     . DC  F 3 2  ? 16.79900  -11.07600 24.93400  1.000 103.86777 ?  18  DC  F H6     1 
ATOM   4670 P  P      . DC  F 3 3  ? 19.35700  -8.66600  20.07900  1.000 109.49662 ?  19  DC  F P      1 
ATOM   4671 O  OP1    . DC  F 3 3  ? 20.23000  -8.62000  18.88500  1.000 108.30108 ?  19  DC  F OP1    1 
ATOM   4672 O  OP2    . DC  F 3 3  ? 19.79600  -7.97500  21.31200  1.000 102.08290 -1 19  DC  F OP2    1 
ATOM   4673 O  "O5'"  . DC  F 3 3  ? 17.93700  -8.07300  19.66300  1.000 95.49280  ?  19  DC  F "O5'"  1 
ATOM   4674 C  "C5'"  . DC  F 3 3  ? 17.09700  -8.80500  18.78200  1.000 90.86862  ?  19  DC  F "C5'"  1 
ATOM   4675 C  "C4'"  . DC  F 3 3  ? 15.83000  -8.02600  18.47100  1.000 85.91336  ?  19  DC  F "C4'"  1 
ATOM   4676 O  "O4'"  . DC  F 3 3  ? 14.84600  -8.24100  19.52400  1.000 83.64643  ?  19  DC  F "O4'"  1 
ATOM   4677 C  "C3'"  . DC  F 3 3  ? 16.02400  -6.51000  18.36400  1.000 83.38705  ?  19  DC  F "C3'"  1 
ATOM   4678 O  "O3'"  . DC  F 3 3  ? 15.34100  -6.02000  17.21900  1.000 84.69486  ?  19  DC  F "O3'"  1 
ATOM   4679 C  "C2'"  . DC  F 3 3  ? 15.45800  -5.97200  19.68200  1.000 78.55664  ?  19  DC  F "C2'"  1 
ATOM   4680 C  "C1'"  . DC  F 3 3  ? 14.37500  -6.99600  20.02700  1.000 79.53869  ?  19  DC  F "C1'"  1 
ATOM   4681 N  N1     . DC  F 3 3  ? 14.09700  -7.16900  21.50100  1.000 74.54422  ?  19  DC  F N1     1 
ATOM   4682 C  C2     . DC  F 3 3  ? 12.76900  -7.30700  21.97300  1.000 71.13163  ?  19  DC  F C2     1 
ATOM   4683 O  O2     . DC  F 3 3  ? 11.82100  -7.25400  21.17800  1.000 67.77883  ?  19  DC  F O2     1 
ATOM   4684 N  N3     . DC  F 3 3  ? 12.56600  -7.48700  23.30900  1.000 72.59153  ?  19  DC  F N3     1 
ATOM   4685 C  C4     . DC  F 3 3  ? 13.60500  -7.55100  24.14000  1.000 75.88617  ?  19  DC  F C4     1 
ATOM   4686 N  N4     . DC  F 3 3  ? 13.35700  -7.73400  25.44600  1.000 77.82236  ?  19  DC  F N4     1 
ATOM   4687 C  C5     . DC  F 3 3  ? 14.94800  -7.41900  23.68300  1.000 74.09097  ?  19  DC  F C5     1 
ATOM   4688 C  C6     . DC  F 3 3  ? 15.14500  -7.24100  22.37300  1.000 78.09835  ?  19  DC  F C6     1 
ATOM   4689 H  "H5'"  . DC  F 3 3  ? 16.85900  -9.64900  19.19600  1.000 109.04235 ?  19  DC  F "H5'"  1 
ATOM   4690 H  "H5''" . DC  F 3 3  ? 17.57500  -8.97900  17.95600  1.000 109.04235 ?  19  DC  F "H5''" 1 
ATOM   4691 H  "H4'"  . DC  F 3 3  ? 15.46400  -8.35100  17.63400  1.000 103.09604 ?  19  DC  F "H4'"  1 
ATOM   4692 H  "H3'"  . DC  F 3 3  ? 16.96900  -6.30200  18.30000  1.000 100.06447 ?  19  DC  F "H3'"  1 
ATOM   4693 H  "H2'"  . DC  F 3 3  ? 16.14600  -5.95000  20.36400  1.000 94.26796  ?  19  DC  F "H2'"  1 
ATOM   4694 H  "H2''" . DC  F 3 3  ? 15.07000  -5.09200  19.55500  1.000 94.26796  ?  19  DC  F "H2''" 1 
ATOM   4695 H  "H1'"  . DC  F 3 3  ? 13.55300  -6.75800  19.57100  1.000 95.44643  ?  19  DC  F "H1'"  1 
ATOM   4696 H  H41    . DC  F 3 3  ? 14.00900  -7.77800  26.00500  1.000 93.38683  ?  19  DC  F H41    1 
ATOM   4697 H  H42    . DC  F 3 3  ? 12.54600  -7.80700  25.72400  1.000 93.38683  ?  19  DC  F H42    1 
ATOM   4698 H  H5     . DC  F 3 3  ? 15.66400  -7.46300  24.27500  1.000 88.90916  ?  19  DC  F H5     1 
ATOM   4699 H  H6     . DC  F 3 3  ? 16.01300  -7.16000  22.05000  1.000 93.71802  ?  19  DC  F H6     1 
ATOM   4700 P  P      . DC  F 3 4  ? 15.42900  -4.47300  16.80500  1.000 83.78160  ?  20  DC  F P      1 
ATOM   4701 O  OP1    . DC  F 3 4  ? 15.73400  -4.43000  15.36200  1.000 89.70839  ?  20  DC  F OP1    1 
ATOM   4702 O  OP2    . DC  F 3 4  ? 16.31000  -3.78800  17.78700  1.000 87.20878  -1 20  DC  F OP2    1 
ATOM   4703 O  "O5'"  . DC  F 3 4  ? 13.92600  -3.98000  16.98300  1.000 74.95413  ?  20  DC  F "O5'"  1 
ATOM   4704 C  "C5'"  . DC  F 3 4  ? 12.88800  -4.88800  16.70300  1.000 70.96032  ?  20  DC  F "C5'"  1 
ATOM   4705 C  "C4'"  . DC  F 3 4  ? 11.56800  -4.34500  17.16100  1.000 65.75426  ?  20  DC  F "C4'"  1 
ATOM   4706 O  "O4'"  . DC  F 3 4  ? 11.36300  -4.59100  18.58200  1.000 68.36789  ?  20  DC  F "O4'"  1 
ATOM   4707 C  "C3'"  . DC  F 3 4  ? 11.40800  -2.84600  16.98600  1.000 62.92225  ?  20  DC  F "C3'"  1 
ATOM   4708 O  "O3'"  . DC  F 3 4  ? 10.10500  -2.62800  16.51200  1.000 58.57852  ?  20  DC  F "O3'"  1 
ATOM   4709 C  "C2'"  . DC  F 3 4  ? 11.67900  -2.28100  18.39200  1.000 57.80546  ?  20  DC  F "C2'"  1 
ATOM   4710 C  "C1'"  . DC  F 3 4  ? 11.09100  -3.36800  19.27800  1.000 60.18717  ?  20  DC  F "C1'"  1 
ATOM   4711 N  N1     . DC  F 3 4  ? 11.66700  -3.51900  20.66900  1.000 56.71210  ?  20  DC  F N1     1 
ATOM   4712 C  C2     . DC  F 3 4  ? 10.82600  -3.84000  21.71700  1.000 56.95846  ?  20  DC  F C2     1 
ATOM   4713 O  O2     . DC  F 3 4  ? 9.62100   -3.93900  21.50600  1.000 60.88633  ?  20  DC  F O2     1 
ATOM   4714 N  N3     . DC  F 3 4  ? 11.34700  -4.02500  22.94800  1.000 62.38821  ?  20  DC  F N3     1 
ATOM   4715 C  C4     . DC  F 3 4  ? 12.65200  -3.91700  23.13700  1.000 62.87952  ?  20  DC  F C4     1 
ATOM   4716 N  N4     . DC  F 3 4  ? 13.12700  -4.09300  24.37800  1.000 66.50013  ?  20  DC  F N4     1 
ATOM   4717 C  C5     . DC  F 3 4  ? 13.52900  -3.60100  22.07600  1.000 56.77972  ?  20  DC  F C5     1 
ATOM   4718 C  C6     . DC  F 3 4  ? 12.99800  -3.42800  20.86700  1.000 59.87085  ?  20  DC  F C6     1 
ATOM   4719 H  "H5'"  . DC  F 3 4  ? 13.06200  -5.72500  17.16000  1.000 85.15239  ?  20  DC  F "H5'"  1 
ATOM   4720 H  "H5''" . DC  F 3 4  ? 12.85300  -5.04800  15.74700  1.000 85.15239  ?  20  DC  F "H5''" 1 
ATOM   4721 H  "H4'"  . DC  F 3 4  ? 10.86300  -4.79000  16.66600  1.000 78.90511  ?  20  DC  F "H4'"  1 
ATOM   4722 H  "H3'"  . DC  F 3 4  ? 12.06100  -2.50900  16.35300  1.000 75.50670  ?  20  DC  F "H3'"  1 
ATOM   4723 H  "H2'"  . DC  F 3 4  ? 12.63100  -2.18200  18.54600  1.000 69.36655  ?  20  DC  F "H2'"  1 
ATOM   4724 H  "H2''" . DC  F 3 4  ? 11.21400  -1.44000  18.52200  1.000 69.36655  ?  20  DC  F "H2''" 1 
ATOM   4725 H  "H1'"  . DC  F 3 4  ? 10.13100  -3.24300  19.34000  1.000 72.22461  ?  20  DC  F "H1'"  1 
ATOM   4726 H  H41    . DC  F 3 4  ? 13.96700  -4.23200  24.50100  1.000 79.80016  ?  20  DC  F H41    1 
ATOM   4727 H  H42    . DC  F 3 4  ? 12.59200  -4.06700  25.05000  1.000 79.80016  ?  20  DC  F H42    1 
ATOM   4728 H  H5     . DC  F 3 4  ? 14.44500  -3.52400  22.21500  1.000 68.13567  ?  20  DC  F H5     1 
ATOM   4729 H  H6     . DC  F 3 4  ? 13.55400  -3.23000  20.14900  1.000 71.84502  ?  20  DC  F H6     1 
ATOM   4730 P  P      . DA  F 3 5  ? 9.73900   -1.26900  15.77000  1.000 64.69013  ?  21  DA  F P      1 
ATOM   4731 O  OP1    . DA  F 3 5  ? 8.75100   -1.68500  14.73900  1.000 56.94636  ?  21  DA  F OP1    1 
ATOM   4732 O  OP2    . DA  F 3 5  ? 10.97200  -0.49300  15.52000  1.000 53.35978  -1 21  DA  F OP2    1 
ATOM   4733 O  "O5'"  . DA  F 3 5  ? 8.94800   -0.45500  16.90700  1.000 56.89390  ?  21  DA  F "O5'"  1 
ATOM   4734 C  "C5'"  . DA  F 3 5  ? 7.77600   -1.00000  17.45000  1.000 50.02426  ?  21  DA  F "C5'"  1 
ATOM   4735 C  "C4'"  . DA  F 3 5  ? 7.36400   -0.21700  18.67900  1.000 50.92858  ?  21  DA  F "C4'"  1 
ATOM   4736 O  "O4'"  . DA  F 3 5  ? 8.22700   -0.56900  19.81500  1.000 46.15901  ?  21  DA  F "O4'"  1 
ATOM   4737 C  "C3'"  . DA  F 3 5  ? 7.48300   1.30200   18.52100  1.000 49.41303  ?  21  DA  F "C3'"  1 
ATOM   4738 O  "O3'"  . DA  F 3 5  ? 6.35200   1.93700   19.14700  1.000 45.58882  ?  21  DA  F "O3'"  1 
ATOM   4739 C  "C2'"  . DA  F 3 5  ? 8.82400   1.59200   19.21400  1.000 46.08208  ?  21  DA  F "C2'"  1 
ATOM   4740 C  "C1'"  . DA  F 3 5  ? 8.76900   0.59900   20.36700  1.000 43.85271  ?  21  DA  F "C1'"  1 
ATOM   4741 N  N9     . DA  F 3 5  ? 10.03100  0.30700   21.00400  1.000 43.24652  ?  21  DA  F N9     1 
ATOM   4742 C  C8     . DA  F 3 5  ? 11.29600  0.54400   20.53700  1.000 47.51554  ?  21  DA  F C8     1 
ATOM   4743 N  N7     . DA  F 3 5  ? 12.25700  0.22400   21.40200  1.000 46.38319  ?  21  DA  F N7     1 
ATOM   4744 C  C5     . DA  F 3 5  ? 11.55800  -0.24900  22.51000  1.000 46.85447  ?  21  DA  F C5     1 
ATOM   4745 C  C6     . DA  F 3 5  ? 11.97900  -0.74200  23.77000  1.000 49.91239  ?  21  DA  F C6     1 
ATOM   4746 N  N6     . DA  F 3 5  ? 13.26000  -0.83500  24.12800  1.000 51.66602  ?  21  DA  F N6     1 
ATOM   4747 N  N1     . DA  F 3 5  ? 11.02400  -1.12600  24.64600  1.000 47.23627  ?  21  DA  F N1     1 
ATOM   4748 C  C2     . DA  F 3 5  ? 9.73500   -0.99500  24.30400  1.000 45.88967  ?  21  DA  F C2     1 
ATOM   4749 N  N3     . DA  F 3 5  ? 9.21200   -0.53200  23.16200  1.000 48.36573  ?  21  DA  F N3     1 
ATOM   4750 C  C4     . DA  F 3 5  ? 10.18800  -0.18200  22.29400  1.000 46.09341  ?  21  DA  F C4     1 
ATOM   4751 H  "H5'"  . DA  F 3 5  ? 7.93500   -1.92500  17.69600  1.000 60.02911  ?  21  DA  F "H5'"  1 
ATOM   4752 H  "H5''" . DA  F 3 5  ? 7.06600   -0.96000  16.79000  1.000 60.02911  ?  21  DA  F "H5''" 1 
ATOM   4753 H  "H4'"  . DA  F 3 5  ? 6.44600   -0.43900  18.90000  1.000 61.11430  ?  21  DA  F "H4'"  1 
ATOM   4754 H  "H3'"  . DA  F 3 5  ? 7.52900   1.54000   17.58200  1.000 59.29563  ?  21  DA  F "H3'"  1 
ATOM   4755 H  "H2'"  . DA  F 3 5  ? 9.56900   1.40000   18.62300  1.000 55.29849  ?  21  DA  F "H2'"  1 
ATOM   4756 H  "H2''" . DA  F 3 5  ? 8.85900   2.50400   19.54000  1.000 55.29849  ?  21  DA  F "H2''" 1 
ATOM   4757 H  "H1'"  . DA  F 3 5  ? 8.15600   0.93800   21.03800  1.000 52.62325  ?  21  DA  F "H1'"  1 
ATOM   4758 H  H8     . DA  F 3 5  ? 11.46900  0.89200   19.69200  1.000 57.01864  ?  21  DA  F H8     1 
ATOM   4759 H  H61    . DA  F 3 5  ? 13.46800  -1.13600  24.90600  1.000 61.99922  ?  21  DA  F H61    1 
ATOM   4760 H  H62    . DA  F 3 5  ? 13.87800  -0.59400  23.58100  1.000 61.99922  ?  21  DA  F H62    1 
ATOM   4761 H  H2     . DA  F 3 5  ? 9.12000   -1.26500  24.94700  1.000 55.06760  ?  21  DA  F H2     1 
ATOM   4762 P  P      . DC  F 3 6  ? 6.05300   3.46800   18.84900  1.000 40.58511  ?  22  DC  F P      1 
ATOM   4763 O  OP1    . DC  F 3 6  ? 4.69300   3.76500   19.40800  1.000 41.52170  ?  22  DC  F OP1    1 
ATOM   4764 O  OP2    . DC  F 3 6  ? 6.37200   3.66900   17.43000  1.000 42.19367  -1 22  DC  F OP2    1 
ATOM   4765 O  "O5'"  . DC  F 3 6  ? 7.20100   4.23200   19.66700  1.000 43.70858  ?  22  DC  F "O5'"  1 
ATOM   4766 C  "C5'"  . DC  F 3 6  ? 6.88900   4.91600   20.83600  1.000 37.47662  ?  22  DC  F "C5'"  1 
ATOM   4767 C  "C4'"  . DC  F 3 6  ? 6.93700   4.00000   22.02600  1.000 35.40050  ?  22  DC  F "C4'"  1 
ATOM   4768 O  "O4'"  . DC  F 3 6  ? 8.23100   3.38600   22.07000  1.000 35.98766  ?  22  DC  F "O4'"  1 
ATOM   4769 C  "C3'"  . DC  F 3 6  ? 6.73600   4.70200   23.38500  1.000 33.87865  ?  22  DC  F "C3'"  1 
ATOM   4770 O  "O3'"  . DC  F 3 6  ? 5.47400   4.29300   24.02500  1.000 32.91116  ?  22  DC  F "O3'"  1 
ATOM   4771 C  "C2'"  . DC  F 3 6  ? 7.94700   4.29700   24.22500  1.000 35.21361  ?  22  DC  F "C2'"  1 
ATOM   4772 C  "C1'"  . DC  F 3 6  ? 8.53600   3.13900   23.43100  1.000 39.25882  ?  22  DC  F "C1'"  1 
ATOM   4773 N  N1     . DC  F 3 6  ? 9.99300   2.99800   23.59600  1.000 39.92399  ?  22  DC  F N1     1 
ATOM   4774 C  C2     . DC  F 3 6  ? 10.47700  2.35300   24.72600  1.000 42.23354  ?  22  DC  F C2     1 
ATOM   4775 O  O2     . DC  F 3 6  ? 9.67700   1.95300   25.57700  1.000 41.56810  ?  22  DC  F O2     1 
ATOM   4776 N  N3     . DC  F 3 6  ? 11.82300  2.18200   24.85600  1.000 42.26177  ?  22  DC  F N3     1 
ATOM   4777 C  C4     . DC  F 3 6  ? 12.63200  2.65800   23.93100  1.000 39.25560  ?  22  DC  F C4     1 
ATOM   4778 N  N4     . DC  F 3 6  ? 13.93100  2.49100   24.10500  1.000 41.98821  ?  22  DC  F N4     1 
ATOM   4779 C  C5     . DC  F 3 6  ? 12.13900  3.34500   22.77500  1.000 34.48401  ?  22  DC  F C5     1 
ATOM   4780 C  C6     . DC  F 3 6  ? 10.82500  3.46200   22.65600  1.000 33.00174  ?  22  DC  F C6     1 
ATOM   4781 H  "H5'"  . DC  F 3 6  ? 5.99800   5.29100   20.75800  1.000 44.97194  ?  22  DC  F "H5'"  1 
ATOM   4782 H  "H5''" . DC  F 3 6  ? 7.52700   5.63600   20.96300  1.000 44.97194  ?  22  DC  F "H5''" 1 
ATOM   4783 H  "H4'"  . DC  F 3 6  ? 6.26300   3.31100   21.92300  1.000 42.48060  ?  22  DC  F "H4'"  1 
ATOM   4784 H  "H3'"  . DC  F 3 6  ? 6.73800   5.66300   23.25600  1.000 40.65438  ?  22  DC  F "H3'"  1 
ATOM   4785 H  "H2'"  . DC  F 3 6  ? 8.57900   5.02700   24.28700  1.000 42.25633  ?  22  DC  F "H2'"  1 
ATOM   4786 H  "H2''" . DC  F 3 6  ? 7.67100   4.00200   25.10600  1.000 42.25633  ?  22  DC  F "H2''" 1 
ATOM   4787 H  "H1'"  . DC  F 3 6  ? 8.10500   2.31500   23.70700  1.000 47.11058  ?  22  DC  F "H1'"  1 
ATOM   4788 H  H41    . DC  F 3 6  ? 14.48500  2.79000   23.51900  1.000 50.38585  ?  22  DC  F H41    1 
ATOM   4789 H  H42    . DC  F 3 6  ? 14.22200  2.08300   24.80400  1.000 50.38585  ?  22  DC  F H42    1 
ATOM   4790 H  H5     . DC  F 3 6  ? 12.71400  3.65200   22.11200  1.000 41.38082  ?  22  DC  F H5     1 
ATOM   4791 H  H6     . DC  F 3 6  ? 10.47300  3.88700   21.90800  1.000 39.60208  ?  22  DC  F H6     1 
ATOM   4792 P  P      . DT  F 3 7  ? 4.85600   5.16800   25.24700  1.000 33.77877  ?  23  DT  F P      1 
ATOM   4793 O  OP1    . DT  F 3 7  ? 3.53900   4.53400   25.58400  1.000 31.25857  ?  23  DT  F OP1    1 
ATOM   4794 O  OP2    . DT  F 3 7  ? 4.91800   6.59400   24.80700  1.000 38.77279  -1 23  DT  F OP2    1 
ATOM   4795 O  "O5'"  . DT  F 3 7  ? 5.92700   4.91800   26.43600  1.000 35.93155  ?  23  DT  F "O5'"  1 
ATOM   4796 C  "C5'"  . DT  F 3 7  ? 5.83000   3.68500   27.16000  1.000 38.35908  ?  23  DT  F "C5'"  1 
ATOM   4797 C  "C4'"  . DT  F 3 7  ? 6.64600   3.72500   28.41600  1.000 35.16001  ?  23  DT  F "C4'"  1 
ATOM   4798 O  "O4'"  . DT  F 3 7  ? 8.06400   3.74100   28.13500  1.000 33.50375  ?  23  DT  F "O4'"  1 
ATOM   4799 C  "C3'"  . DT  F 3 7  ? 6.40700   4.97800   29.28000  1.000 33.77901  ?  23  DT  F "C3'"  1 
ATOM   4800 O  "O3'"  . DT  F 3 7  ? 6.28700   4.52500   30.60100  1.000 40.91070  ?  23  DT  F "O3'"  1 
ATOM   4801 C  "C2'"  . DT  F 3 7  ? 7.65200   5.86200   29.03200  1.000 36.21483  ?  23  DT  F "C2'"  1 
ATOM   4802 C  "C1'"  . DT  F 3 7  ? 8.71400   4.80600   28.87500  1.000 35.80756  ?  23  DT  F "C1'"  1 
ATOM   4803 N  N1     . DT  F 3 7  ? 9.91600   5.14000   28.11800  1.000 36.99408  ?  23  DT  F N1     1 
ATOM   4804 C  C2     . DT  F 3 7  ? 11.13300  4.79600   28.64500  1.000 39.40035  ?  23  DT  F C2     1 
ATOM   4805 O  O2     . DT  F 3 7  ? 11.25800  4.32200   29.76100  1.000 41.22004  ?  23  DT  F O2     1 
ATOM   4806 N  N3     . DT  F 3 7  ? 12.20900  5.05700   27.81900  1.000 36.18824  ?  23  DT  F N3     1 
ATOM   4807 C  C4     . DT  F 3 7  ? 12.15900  5.54600   26.53100  1.000 40.35922  ?  23  DT  F C4     1 
ATOM   4808 O  O4     . DT  F 3 7  ? 13.16400  5.74300   25.86400  1.000 35.47828  ?  23  DT  F O4     1 
ATOM   4809 C  C5     . DT  F 3 7  ? 10.85400  5.88400   26.05900  1.000 34.25844  ?  23  DT  F C5     1 
ATOM   4810 C  C7     . DT  F 3 7  ? 10.69400  6.48500   24.68400  1.000 41.11133  ?  23  DT  F C7     1 
ATOM   4811 C  C6     . DT  F 3 7  ? 9.80900   5.63100   26.84900  1.000 35.19281  ?  23  DT  F C6     1 
ATOM   4812 H  "H5'"  . DT  F 3 7  ? 6.14800   2.96100   26.59800  1.000 46.03090  ?  23  DT  F "H5'"  1 
ATOM   4813 H  "H5''" . DT  F 3 7  ? 4.90200   3.52400   27.39000  1.000 46.03090  ?  23  DT  F "H5''" 1 
ATOM   4814 H  "H4'"  . DT  F 3 7  ? 6.44200   2.93800   28.94500  1.000 42.19201  ?  23  DT  F "H4'"  1 
ATOM   4815 H  "H3'"  . DT  F 3 7  ? 5.59900   5.43600   28.99900  1.000 40.53482  ?  23  DT  F "H3'"  1 
ATOM   4816 H  "H2'"  . DT  F 3 7  ? 7.55400   6.38300   28.22000  1.000 43.45780  ?  23  DT  F "H2'"  1 
ATOM   4817 H  "H2''" . DT  F 3 7  ? 7.83500   6.43000   29.79700  1.000 43.45780  ?  23  DT  F "H2''" 1 
ATOM   4818 H  "H1'"  . DT  F 3 7  ? 8.96600   4.47600   29.75100  1.000 42.96908  ?  23  DT  F "H1'"  1 
ATOM   4819 H  H3     . DT  F 3 7  ? 12.98600  4.85300   28.12300  1.000 43.42588  ?  23  DT  F H3     1 
ATOM   4820 H  H71    . DT  F 3 7  ? 11.43400  7.08600   24.50600  1.000 49.33359  ?  23  DT  F H71    1 
ATOM   4821 H  H72    . DT  F 3 7  ? 10.68600  5.77900   24.02100  1.000 49.33359  ?  23  DT  F H72    1 
ATOM   4822 H  H73    . DT  F 3 7  ? 9.86000   6.97900   24.64200  1.000 49.33359  ?  23  DT  F H73    1 
ATOM   4823 H  H6     . DT  F 3 7  ? 8.95900   5.82800   26.52700  1.000 42.23137  ?  23  DT  F H6     1 
ATOM   4824 P  P      . DT  F 3 8  ? 5.71700   5.44700   31.77200  1.000 39.31209  ?  24  DT  F P      1 
ATOM   4825 O  OP1    . DT  F 3 8  ? 5.06500   4.45100   32.64900  1.000 42.32981  ?  24  DT  F OP1    1 
ATOM   4826 O  OP2    . DT  F 3 8  ? 4.91500   6.60500   31.34300  1.000 39.72544  -1 24  DT  F OP2    1 
ATOM   4827 O  "O5'"  . DT  F 3 8  ? 7.06200   6.00400   32.38900  1.000 36.80579  ?  24  DT  F "O5'"  1 
ATOM   4828 C  "C5'"  . DT  F 3 8  ? 7.85200   5.11100   33.13300  1.000 42.34964  ?  24  DT  F "C5'"  1 
ATOM   4829 C  "C4'"  . DT  F 3 8  ? 9.19700   5.71200   33.49100  1.000 36.73824  ?  24  DT  F "C4'"  1 
ATOM   4830 O  "O4'"  . DT  F 3 8  ? 9.96200   5.97100   32.33200  1.000 34.87417  ?  24  DT  F "O4'"  1 
ATOM   4831 C  "C3'"  . DT  F 3 8  ? 9.13900   7.04900   34.23000  1.000 37.21775  ?  24  DT  F "C3'"  1 
ATOM   4832 O  "O3'"  . DT  F 3 8  ? 9.53900   6.79100   35.58900  1.000 41.35030  ?  24  DT  F "O3'"  1 
ATOM   4833 C  "C2'"  . DT  F 3 8  ? 10.09500  7.98700   33.44300  1.000 35.83199  ?  24  DT  F "C2'"  1 
ATOM   4834 C  "C1'"  . DT  F 3 8  ? 10.87400  7.01000   32.60000  1.000 34.06393  ?  24  DT  F "C1'"  1 
ATOM   4835 N  N1     . DT  F 3 8  ? 11.41800  7.48000   31.25500  1.000 39.64314  ?  24  DT  F N1     1 
ATOM   4836 C  C2     . DT  F 3 8  ? 12.76800  7.32300   31.02200  1.000 41.02490  ?  24  DT  F C2     1 
ATOM   4837 O  O2     . DT  F 3 8  ? 13.53800  6.88700   31.85200  1.000 39.41182  ?  24  DT  F O2     1 
ATOM   4838 N  N3     . DT  F 3 8  ? 13.18400  7.70900   29.79600  1.000 39.41284  ?  24  DT  F N3     1 
ATOM   4839 C  C4     . DT  F 3 8  ? 12.40100  8.21000   28.75600  1.000 39.14224  ?  24  DT  F C4     1 
ATOM   4840 O  O4     . DT  F 3 8  ? 12.88100  8.55100   27.68700  1.000 37.63847  ?  24  DT  F O4     1 
ATOM   4841 C  C5     . DT  F 3 8  ? 10.99800  8.36600   29.06500  1.000 37.91992  ?  24  DT  F C5     1 
ATOM   4842 C  C7     . DT  F 3 8  ? 10.06300  8.91000   28.02400  1.000 36.62412  ?  24  DT  F C7     1 
ATOM   4843 C  C6     . DT  F 3 8  ? 10.57500  7.97700   30.29000  1.000 33.93071  ?  24  DT  F C6     1 
ATOM   4844 H  "H5'"  . DT  F 3 8  ? 7.99500   4.30600   32.61100  1.000 50.81957  ?  24  DT  F "H5'"  1 
ATOM   4845 H  "H5''" . DT  F 3 8  ? 7.38200   4.87900   33.94900  1.000 50.81957  ?  24  DT  F "H5''" 1 
ATOM   4846 H  "H4'"  . DT  F 3 8  ? 9.68000   5.07700   34.04300  1.000 44.08588  ?  24  DT  F "H4'"  1 
ATOM   4847 H  "H3'"  . DT  F 3 8  ? 8.23500   7.40000   34.20900  1.000 44.66130  ?  24  DT  F "H3'"  1 
ATOM   4848 H  "H2'"  . DT  F 3 8  ? 9.59300   8.60100   32.88500  1.000 42.99838  ?  24  DT  F "H2'"  1 
ATOM   4849 H  "H2''" . DT  F 3 8  ? 10.68300  8.46700   34.04700  1.000 42.99838  ?  24  DT  F "H2''" 1 
ATOM   4850 H  "H1'"  . DT  F 3 8  ? 11.60500  6.65500   33.12900  1.000 40.87671  ?  24  DT  F "H1'"  1 
ATOM   4851 H  H3     . DT  F 3 8  ? 14.02500  7.62800   29.63500  1.000 47.29541  ?  24  DT  F H3     1 
ATOM   4852 H  H71    . DT  F 3 8  ? 9.29900   8.31900   27.93500  1.000 43.94895  ?  24  DT  F H71    1 
ATOM   4853 H  H72    . DT  F 3 8  ? 9.76000   9.79200   28.29100  1.000 43.94895  ?  24  DT  F H72    1 
ATOM   4854 H  H73    . DT  F 3 8  ? 10.52500  8.97100   27.17400  1.000 43.94895  ?  24  DT  F H73    1 
ATOM   4855 H  H6     . DT  F 3 8  ? 9.66900   8.04500   30.48700  1.000 40.71685  ?  24  DT  F H6     1 
ATOM   4856 P  P      . DC  F 3 9  ? 9.53800   7.98000   36.66000  1.000 43.85928  ?  25  DC  F P      1 
ATOM   4857 O  OP1    . DC  F 3 9  ? 9.58800   7.22700   37.93200  1.000 48.15050  ?  25  DC  F OP1    1 
ATOM   4858 O  OP2    . DC  F 3 9  ? 8.46800   8.95700   36.28800  1.000 44.76566  -1 25  DC  F OP2    1 
ATOM   4859 O  "O5'"  . DC  F 3 9  ? 10.95300  8.69300   36.48100  1.000 41.90689  ?  25  DC  F "O5'"  1 
ATOM   4860 C  "C5'"  . DC  F 3 9  ? 12.08300  7.91100   36.66800  1.000 41.72084  ?  25  DC  F "C5'"  1 
ATOM   4861 C  "C4'"  . DC  F 3 9  ? 13.33000  8.62600   36.28300  1.000 45.61167  ?  25  DC  F "C4'"  1 
ATOM   4862 O  "O4'"  . DC  F 3 9  ? 13.37000  8.77800   34.86400  1.000 47.15594  ?  25  DC  F "O4'"  1 
ATOM   4863 C  "C3'"  . DC  F 3 9  ? 13.50500  10.03000  36.85600  1.000 51.34763  ?  25  DC  F "C3'"  1 
ATOM   4864 O  "O3'"  . DC  F 3 9  ? 14.55500  9.96500   37.85900  1.000 58.08076  ?  25  DC  F "O3'"  1 
ATOM   4865 C  "C2'"  . DC  F 3 9  ? 13.87400  10.91300  35.63900  1.000 49.57834  ?  25  DC  F "C2'"  1 
ATOM   4866 C  "C1'"  . DC  F 3 9  ? 14.21100  9.88100   34.56300  1.000 47.07868  ?  25  DC  F "C1'"  1 
ATOM   4867 N  N1     . DC  F 3 9  ? 13.95200  10.26800  33.09400  1.000 45.93194  ?  25  DC  F N1     1 
ATOM   4868 C  C2     . DC  F 3 9  ? 15.01500  10.27600  32.19200  1.000 43.53257  ?  25  DC  F C2     1 
ATOM   4869 O  O2     . DC  F 3 9  ? 16.14800  10.00600  32.61000  1.000 43.87505  ?  25  DC  F O2     1 
ATOM   4870 N  N3     . DC  F 3 9  ? 14.78000  10.58800  30.89800  1.000 44.56908  ?  25  DC  F N3     1 
ATOM   4871 C  C4     . DC  F 3 9  ? 13.54300  10.85900  30.48000  1.000 42.61408  ?  25  DC  F C4     1 
ATOM   4872 N  N4     . DC  F 3 9  ? 13.36300  11.14500  29.16000  1.000 40.81695  ?  25  DC  F N4     1 
ATOM   4873 C  C5     . DC  F 3 9  ? 12.43800  10.83800  31.37900  1.000 41.80308  ?  25  DC  F C5     1 
ATOM   4874 C  C6     . DC  F 3 9  ? 12.68600  10.51800  32.66600  1.000 47.10480  ?  25  DC  F C6     1 
ATOM   4875 H  "H5'"  . DC  F 3 9  ? 12.00200  7.10800   36.13000  1.000 50.06501  ?  25  DC  F "H5'"  1 
ATOM   4876 H  "H5''" . DC  F 3 9  ? 12.14000  7.66000   37.60300  1.000 50.06501  ?  25  DC  F "H5''" 1 
ATOM   4877 H  "H4'"  . DC  F 3 9  ? 14.08900  8.08700   36.55600  1.000 54.73401  ?  25  DC  F "H4'"  1 
ATOM   4878 H  "H3'"  . DC  F 3 9  ? 12.67500  10.33500  37.25500  1.000 61.61716  ?  25  DC  F "H3'"  1 
ATOM   4879 H  "H2'"  . DC  F 3 9  ? 13.11800  11.45700  35.36800  1.000 59.49401  ?  25  DC  F "H2'"  1 
ATOM   4880 H  "H2''" . DC  F 3 9  ? 14.64500  11.46600  35.83800  1.000 59.49401  ?  25  DC  F "H2''" 1 
ATOM   4881 H  "H1'"  . DC  F 3 9  ? 15.13600  9.61000   34.66300  1.000 56.49442  ?  25  DC  F "H1'"  1 
ATOM   4882 H  H41    . DC  F 3 9  ? 12.57600  11.32400  28.86200  1.000 48.98034  ?  25  DC  F H41    1 
ATOM   4883 H  H42    . DC  F 3 9  ? 14.03600  11.14700  28.62500  1.000 48.98034  ?  25  DC  F H42    1 
ATOM   4884 H  H5     . DC  F 3 9  ? 11.57500  11.02500  31.08700  1.000 50.16370  ?  25  DC  F H5     1 
ATOM   4885 H  H6     . DC  F 3 9  ? 11.98500  10.50300  33.27700  1.000 56.52576  ?  25  DC  F H6     1 
ATOM   4886 P  P      . DC  F 3 10 ? 14.84000  11.19100  38.85100  1.000 52.72260  ?  26  DC  F P      1 
ATOM   4887 O  OP1    . DC  F 3 10 ? 15.62300  10.62800  39.97700  1.000 67.79594  ?  26  DC  F OP1    1 
ATOM   4888 O  OP2    . DC  F 3 10 ? 13.56100  11.92700  39.04900  1.000 54.21861  -1 26  DC  F OP2    1 
ATOM   4889 O  "O5'"  . DC  F 3 10 ? 15.84600  12.13900  38.03900  1.000 59.22076  ?  26  DC  F "O5'"  1 
ATOM   4890 C  "C5'"  . DC  F 3 10 ? 17.08100  11.66000  37.64900  1.000 58.02856  ?  26  DC  F "C5'"  1 
ATOM   4891 C  "C4'"  . DC  F 3 10 ? 17.66500  12.53400  36.58400  1.000 63.06267  ?  26  DC  F "C4'"  1 
ATOM   4892 O  "O4'"  . DC  F 3 10 ? 16.89400  12.42300  35.36700  1.000 63.56694  ?  26  DC  F "O4'"  1 
ATOM   4893 C  "C3'"  . DC  F 3 10 ? 17.67100  14.04100  36.87900  1.000 67.91267  ?  26  DC  F "C3'"  1 
ATOM   4894 O  "O3'"  . DC  F 3 10 ? 18.92800  14.42800  37.45900  1.000 71.39197  ?  26  DC  F "O3'"  1 
ATOM   4895 C  "C2'"  . DC  F 3 10 ? 17.43400  14.70200  35.50100  1.000 68.25430  ?  26  DC  F "C2'"  1 
ATOM   4896 C  "C1'"  . DC  F 3 10 ? 17.27100  13.50700  34.55400  1.000 62.37040  ?  26  DC  F "C1'"  1 
ATOM   4897 N  N1     . DC  F 3 10 ? 16.25200  13.70400  33.51100  1.000 57.70146  ?  26  DC  F N1     1 
ATOM   4898 C  C2     . DC  F 3 10 ? 16.66100  13.86300  32.16900  1.000 52.07599  ?  26  DC  F C2     1 
ATOM   4899 O  O2     . DC  F 3 10 ? 17.86200  13.84300  31.90400  1.000 52.10782  ?  26  DC  F O2     1 
ATOM   4900 N  N3     . DC  F 3 10 ? 15.73400  14.05800  31.23600  1.000 53.29189  ?  26  DC  F N3     1 
ATOM   4901 C  C4     . DC  F 3 10 ? 14.43900  14.07400  31.56600  1.000 53.64942  ?  26  DC  F C4     1 
ATOM   4902 N  N4     . DC  F 3 10 ? 13.54000  14.25600  30.57700  1.000 43.34428  ?  26  DC  F N4     1 
ATOM   4903 C  C5     . DC  F 3 10 ? 14.00800  13.92900  32.93700  1.000 46.62532  ?  26  DC  F C5     1 
ATOM   4904 C  C6     . DC  F 3 10 ? 14.94300  13.73800  33.85200  1.000 52.47299  ?  26  DC  F C6     1 
ATOM   4905 H  "H5'"  . DC  F 3 10 ? 16.98100  10.75900  37.30500  1.000 69.63427  ?  26  DC  F "H5'"  1 
ATOM   4906 H  "H5''" . DC  F 3 10 ? 17.67600  11.64700  38.41500  1.000 69.63427  ?  26  DC  F "H5''" 1 
ATOM   4907 H  "H4'"  . DC  F 3 10 ? 18.57400  12.24600  36.40600  1.000 75.67520  ?  26  DC  F "H4'"  1 
ATOM   4908 H  "H3'"  . DC  F 3 10 ? 16.94500  14.26300  37.48200  1.000 81.49520  ?  26  DC  F "H3'"  1 
ATOM   4909 H  "H2'"  . DC  F 3 10 ? 16.62700  15.23900  35.51500  1.000 81.90517  ?  26  DC  F "H2'"  1 
ATOM   4910 H  "H2''" . DC  F 3 10 ? 18.19900  15.23900  35.24300  1.000 81.90517  ?  26  DC  F "H2''" 1 
ATOM   4911 H  "H1'"  . DC  F 3 10 ? 18.12400  13.31100  34.13800  1.000 74.84448  ?  26  DC  F "H1'"  1 
ATOM   4912 H  H41    . DC  F 3 10 ? 12.69900  14.27100  30.75800  1.000 52.01314  ?  26  DC  F H41    1 
ATOM   4913 H  H42    . DC  F 3 10 ? 13.80800  14.35700  29.76600  1.000 52.01314  ?  26  DC  F H42    1 
ATOM   4914 H  H5     . DC  F 3 10 ? 13.10600  13.93700  33.16300  1.000 55.95039  ?  26  DC  F H5     1 
ATOM   4915 H  H6     . DC  F 3 10 ? 14.69800  13.63100  34.74300  1.000 62.96758  ?  26  DC  F H6     1 
ATOM   4916 P  P      . DT  F 3 11 ? 19.24500  15.96300  37.80300  1.000 76.45954  ?  27  DT  F P      1 
ATOM   4917 O  OP1    . DT  F 3 11 ? 20.26000  15.91900  38.88100  1.000 84.63076  ?  27  DT  F OP1    1 
ATOM   4918 O  OP2    . DT  F 3 11 ? 17.99200  16.70300  38.06200  1.000 80.98822  -1 27  DT  F OP2    1 
ATOM   4919 O  "O5'"  . DT  F 3 11 ? 19.94600  16.47200  36.48200  1.000 74.61502  ?  27  DT  F "O5'"  1 
ATOM   4920 C  "C5'"  . DT  F 3 11 ? 20.94600  15.62700  35.86900  1.000 78.56482  ?  27  DT  F "C5'"  1 
ATOM   4921 C  "C4'"  . DT  F 3 11 ? 21.52000  16.29400  34.63200  1.000 81.92244  ?  27  DT  F "C4'"  1 
ATOM   4922 O  "O4'"  . DT  F 3 11 ? 20.58300  16.14400  33.53900  1.000 75.10795  ?  27  DT  F "O4'"  1 
ATOM   4923 C  "C3'"  . DT  F 3 11 ? 21.76400  17.79600  34.80700  1.000 83.76647  ?  27  DT  F "C3'"  1 
ATOM   4924 O  "O3'"  . DT  F 3 11 ? 23.00900  18.17800  34.26600  1.000 85.52902  ?  27  DT  F "O3'"  1 
ATOM   4925 C  "C2'"  . DT  F 3 11 ? 20.58700  18.44100  34.08700  1.000 77.58013  ?  27  DT  F "C2'"  1 
ATOM   4926 C  "C1'"  . DT  F 3 11 ? 20.25700  17.40800  33.01500  1.000 76.19245  ?  27  DT  F "C1'"  1 
ATOM   4927 N  N1     . DT  F 3 11 ? 18.80300  17.43500  32.58900  1.000 70.26647  ?  27  DT  F N1     1 
ATOM   4928 C  C2     . DT  F 3 11 ? 18.52600  17.36400  31.25100  1.000 65.15333  ?  27  DT  F C2     1 
ATOM   4929 O  O2     . DT  F 3 11 ? 19.41300  17.24400  30.39200  1.000 60.26559  ?  27  DT  F O2     1 
ATOM   4930 N  N3     . DT  F 3 11 ? 17.17200  17.42300  30.93500  1.000 60.09312  ?  27  DT  F N3     1 
ATOM   4931 C  C4     . DT  F 3 11 ? 16.10900  17.55400  31.82200  1.000 62.46481  ?  27  DT  F C4     1 
ATOM   4932 O  O4     . DT  F 3 11 ? 14.95300  17.61200  31.45000  1.000 58.12900  ?  27  DT  F O4     1 
ATOM   4933 C  C5     . DT  F 3 11 ? 16.47500  17.63100  33.22100  1.000 64.29799  ?  27  DT  F C5     1 
ATOM   4934 C  C7     . DT  F 3 11 ? 15.41100  17.76700  34.26000  1.000 58.18614  ?  27  DT  F C7     1 
ATOM   4935 C  C6     . DT  F 3 11 ? 17.79000  17.57300  33.53800  1.000 67.85246  ?  27  DT  F C6     1 
ATOM   4936 H  "H5'"  . DT  F 3 11 ? 20.54100  14.78200  35.61800  1.000 94.27778  ?  27  DT  F "H5'"  1 
ATOM   4937 H  "H5''" . DT  F 3 11 ? 21.66000  15.46300  36.50500  1.000 94.27778  ?  27  DT  F "H5''" 1 
ATOM   4938 H  "H4'"  . DT  F 3 11 ? 22.35600  15.86100  34.39600  1.000 98.30693  ?  27  DT  F "H4'"  1 
ATOM   4939 H  "H3'"  . DT  F 3 11 ? 21.73400  18.02300  35.74900  1.000 100.51976 ?  27  DT  F "H3'"  1 
ATOM   4940 H  "H2'"  . DT  F 3 11 ? 19.84400  18.56500  34.69400  1.000 93.09616  ?  27  DT  F "H2'"  1 
ATOM   4941 H  "H2''" . DT  F 3 11 ? 20.84800  19.28300  33.68300  1.000 93.09616  ?  27  DT  F "H2''" 1 
ATOM   4942 H  "H1'"  . DT  F 3 11 ? 20.81400  17.57700  32.23900  1.000 91.43094  ?  27  DT  F "H1'"  1 
ATOM   4943 H  H3     . DT  F 3 11 ? 16.97100  17.37800  30.10200  1.000 72.11174  ?  27  DT  F H3     1 
ATOM   4944 H  H71    . DT  F 3 11 ? 14.56400  17.96500  33.83200  1.000 69.82337  ?  27  DT  F H71    1 
ATOM   4945 H  H72    . DT  F 3 11 ? 15.33600  16.93800  34.75700  1.000 69.82337  ?  27  DT  F H72    1 
ATOM   4946 H  H73    . DT  F 3 11 ? 15.64200  18.48800  34.86700  1.000 69.82337  ?  27  DT  F H73    1 
ATOM   4947 H  H6     . DT  F 3 11 ? 18.03000  17.62600  34.43500  1.000 81.42295  ?  27  DT  F H6     1 
ATOM   4948 P  P      . DT  F 3 12 ? 23.47700  19.71600  34.33900  1.000 92.04046  ?  28  DT  F P      1 
ATOM   4949 O  OP1    . DT  F 3 12 ? 24.91200  19.67400  34.70200  1.000 96.49300  ?  28  DT  F OP1    1 
ATOM   4950 O  OP2    . DT  F 3 12 ? 22.54000  20.48600  35.21600  1.000 81.69766  -1 28  DT  F OP2    1 
ATOM   4951 O  "O5'"  . DT  F 3 12 ? 23.36400  20.18100  32.80000  1.000 86.26800  ?  28  DT  F "O5'"  1 
ATOM   4952 C  "C5'"  . DT  F 3 12 ? 23.92000  19.33600  31.77500  1.000 81.48295  ?  28  DT  F "C5'"  1 
ATOM   4953 C  "C4'"  . DT  F 3 12 ? 23.43900  19.76900  30.40600  1.000 78.08475  ?  28  DT  F "C4'"  1 
ATOM   4954 O  "O4'"  . DT  F 3 12 ? 22.01700  19.49400  30.27400  1.000 73.93449  ?  28  DT  F "O4'"  1 
ATOM   4955 C  "C3'"  . DT  F 3 12 ? 23.62500  21.26300  30.14300  1.000 76.43017  ?  28  DT  F "C3'"  1 
ATOM   4956 O  "O3'"  . DT  F 3 12 ? 24.43300  21.47600  29.00300  1.000 75.52137  ?  28  DT  F "O3'"  1 
ATOM   4957 C  "C2'"  . DT  F 3 12 ? 22.21100  21.81100  29.94800  1.000 73.74148  ?  28  DT  F "C2'"  1 
ATOM   4958 C  "C1'"  . DT  F 3 12 ? 21.40300  20.56500  29.60900  1.000 70.97802  ?  28  DT  F "C1'"  1 
ATOM   4959 N  N1     . DT  F 3 12 ? 19.98400  20.67200  30.02500  1.000 67.37385  ?  28  DT  F N1     1 
ATOM   4960 C  C2     . DT  F 3 12 ? 19.03700  20.70900  29.04800  1.000 61.88574  ?  28  DT  F C2     1 
ATOM   4961 O  O2     . DT  F 3 12 ? 19.30500  20.61700  27.87600  1.000 66.61171  ?  28  DT  F O2     1 
ATOM   4962 N  N3     . DT  F 3 12 ? 17.75800  20.81500  29.49100  1.000 60.50516  ?  28  DT  F N3     1 
ATOM   4963 C  C4     . DT  F 3 12 ? 17.32700  20.92100  30.77500  1.000 58.69221  ?  28  DT  F C4     1 
ATOM   4964 O  O4     . DT  F 3 12 ? 16.15500  21.03200  31.04100  1.000 60.05602  ?  28  DT  F O4     1 
ATOM   4965 C  C5     . DT  F 3 12 ? 18.35800  20.90700  31.78100  1.000 64.19343  ?  28  DT  F C5     1 
ATOM   4966 C  C7     . DT  F 3 12 ? 17.98300  21.00900  33.21900  1.000 66.93324  ?  28  DT  F C7     1 
ATOM   4967 C  C6     . DT  F 3 12 ? 19.63800  20.78300  31.37000  1.000 68.11004  ?  28  DT  F C6     1 
ATOM   4968 H  "H5'"  . DT  F 3 12 ? 23.64700  18.41900  31.93400  1.000 97.77953  ?  28  DT  F "H5'"  1 
ATOM   4969 H  "H5''" . DT  F 3 12 ? 24.88800  19.39100  31.80600  1.000 97.77953  ?  28  DT  F "H5''" 1 
ATOM   4970 H  "H4'"  . DT  F 3 12 ? 23.92100  19.26800  29.73000  1.000 93.70170  ?  28  DT  F "H4'"  1 
ATOM   4971 H  "H3'"  . DT  F 3 12 ? 24.03400  21.68200  30.91600  1.000 91.71621  ?  28  DT  F "H3'"  1 
ATOM   4972 H  "H2'"  . DT  F 3 12 ? 21.88700  22.21800  30.76600  1.000 88.48977  ?  28  DT  F "H2'"  1 
ATOM   4973 H  "H2''" . DT  F 3 12 ? 22.18600  22.44400  29.21400  1.000 88.48977  ?  28  DT  F "H2''" 1 
ATOM   4974 H  "H1'"  . DT  F 3 12 ? 21.44600  20.41000  28.65300  1.000 85.17363  ?  28  DT  F "H1'"  1 
ATOM   4975 H  H3     . DT  F 3 12 ? 17.14800  20.83300  28.88500  1.000 72.60620  ?  28  DT  F H3     1 
ATOM   4976 H  H71    . DT  F 3 12 ? 18.44800  20.32400  33.72400  1.000 80.31989  ?  28  DT  F H71    1 
ATOM   4977 H  H72    . DT  F 3 12 ? 18.23200  21.88400  33.55700  1.000 80.31989  ?  28  DT  F H72    1 
ATOM   4978 H  H73    . DT  F 3 12 ? 17.02600  20.88700  33.31400  1.000 80.31989  ?  28  DT  F H73    1 
ATOM   4979 H  H6     . DT  F 3 12 ? 20.31400  20.77000  32.00900  1.000 81.73205  ?  28  DT  F H6     1 
ATOM   4980 P  P      . DT  F 3 13 ? 24.81300  22.97700  28.57100  1.000 85.67204  ?  29  DT  F P      1 
ATOM   4981 O  OP1    . DT  F 3 13 ? 26.16600  22.86300  27.96400  1.000 79.47350  ?  29  DT  F OP1    1 
ATOM   4982 O  OP2    . DT  F 3 13 ? 24.51200  23.89800  29.70300  1.000 73.65245  -1 29  DT  F OP2    1 
ATOM   4983 O  "O5'"  . DT  F 3 13 ? 23.75400  23.34300  27.43100  1.000 71.89334  ?  29  DT  F "O5'"  1 
ATOM   4984 C  "C5'"  . DT  F 3 13 ? 23.61600  22.49200  26.31200  1.000 68.49668  ?  29  DT  F "C5'"  1 
ATOM   4985 C  "C4'"  . DT  F 3 13 ? 22.44500  22.91200  25.44600  1.000 67.17377  ?  29  DT  F "C4'"  1 
ATOM   4986 O  "O4'"  . DT  F 3 13 ? 21.19800  22.77600  26.18500  1.000 64.38571  ?  29  DT  F "O4'"  1 
ATOM   4987 C  "C3'"  . DT  F 3 13 ? 22.48800  24.36500  24.96000  1.000 62.70988  ?  29  DT  F "C3'"  1 
ATOM   4988 O  "O3'"  . DT  F 3 13 ? 22.24900  24.37900  23.56800  1.000 67.80188  ?  29  DT  F "O3'"  1 
ATOM   4989 C  "C2'"  . DT  F 3 13 ? 21.38000  25.05100  25.74700  1.000 61.32910  ?  29  DT  F "C2'"  1 
ATOM   4990 C  "C1'"  . DT  F 3 13 ? 20.39600  23.89900  25.92200  1.000 62.83789  ?  29  DT  F "C1'"  1 
ATOM   4991 N  N1     . DT  F 3 13 ? 19.41300  24.05400  27.02000  1.000 65.36022  ?  29  DT  F N1     1 
ATOM   4992 C  C2     . DT  F 3 13 ? 18.07600  24.06000  26.70000  1.000 61.56810  ?  29  DT  F C2     1 
ATOM   4993 O  O2     . DT  F 3 13 ? 17.67000  23.96700  25.56400  1.000 59.85905  ?  29  DT  F O2     1 
ATOM   4994 N  N3     . DT  F 3 13 ? 17.23500  24.18500  27.75700  1.000 57.89875  ?  29  DT  F N3     1 
ATOM   4995 C  C4     . DT  F 3 13 ? 17.57700  24.28900  29.09700  1.000 65.40652  ?  29  DT  F C4     1 
ATOM   4996 O  O4     . DT  F 3 13 ? 16.71600  24.39800  30.00100  1.000 63.46175  ?  29  DT  F O4     1 
ATOM   4997 C  C5     . DT  F 3 13 ? 19.00400  24.26600  29.36400  1.000 63.26846  ?  29  DT  F C5     1 
ATOM   4998 C  C7     . DT  F 3 13 ? 19.51100  24.38600  30.77600  1.000 61.90974  ?  29  DT  F C7     1 
ATOM   4999 C  C6     . DT  F 3 13 ? 19.84200  24.14300  28.32000  1.000 64.45942  ?  29  DT  F C6     1 
ATOM   5000 H  "H5'"  . DT  F 3 13 ? 23.47400  21.58300  26.61900  1.000 82.19601  ?  29  DT  F "H5'"  1 
ATOM   5001 H  "H5''" . DT  F 3 13 ? 24.42900  22.52600  25.78500  1.000 82.19601  ?  29  DT  F "H5''" 1 
ATOM   5002 H  "H4'"  . DT  F 3 13 ? 22.41000  22.32900  24.67200  1.000 80.60853  ?  29  DT  F "H4'"  1 
ATOM   5003 H  "H3'"  . DT  F 3 13 ? 23.34800  24.76500  25.16300  1.000 75.25186  ?  29  DT  F "H3'"  1 
ATOM   5004 H  "H2'"  . DT  F 3 13 ? 21.70500  25.36500  26.60500  1.000 73.59492  ?  29  DT  F "H2'"  1 
ATOM   5005 H  "H2''" . DT  F 3 13 ? 20.98400  25.77300  25.23400  1.000 73.59492  ?  29  DT  F "H2''" 1 
ATOM   5006 H  "H1'"  . DT  F 3 13 ? 19.92200  23.75900  25.08800  1.000 75.40547  ?  29  DT  F "H1'"  1 
ATOM   5007 H  H3     . DT  F 3 13 ? 16.39400  24.19300  27.57600  1.000 69.47850  ?  29  DT  F H3     1 
ATOM   5008 H  H71    . DT  F 3 13 ? 20.02700  23.59700  31.00200  1.000 74.29169  ?  29  DT  F H71    1 
ATOM   5009 H  H72    . DT  F 3 13 ? 20.07400  25.17300  30.85200  1.000 74.29169  ?  29  DT  F H72    1 
ATOM   5010 H  H73    . DT  F 3 13 ? 18.76000  24.46600  31.38400  1.000 74.29169  ?  29  DT  F H73    1 
ATOM   5011 H  H6     . DT  F 3 13 ? 20.75700  24.13000  28.48600  1.000 77.35131  ?  29  DT  F H6     1 
ATOM   5012 P  P      . DT  F 3 14 ? 22.64600  25.63900  22.65700  1.000 74.41058  ?  30  DT  F P      1 
ATOM   5013 O  OP1    . DT  F 3 14 ? 23.31600  25.06600  21.44700  1.000 71.71596  ?  30  DT  F OP1    1 
ATOM   5014 O  OP2    . DT  F 3 14 ? 23.27000  26.67400  23.51400  1.000 72.06349  -1 30  DT  F OP2    1 
ATOM   5015 O  "O5'"  . DT  F 3 14 ? 21.23700  26.19600  22.18400  1.000 67.58746  ?  30  DT  F "O5'"  1 
ATOM   5016 C  "C5'"  . DT  F 3 14 ? 20.36200  25.31400  21.54900  1.000 65.13533  ?  30  DT  F "C5'"  1 
ATOM   5017 C  "C4'"  . DT  F 3 14 ? 18.94900  25.76200  21.71700  1.000 62.03150  ?  30  DT  F "C4'"  1 
ATOM   5018 O  "O4'"  . DT  F 3 14 ? 18.58100  25.81200  23.09200  1.000 63.32827  ?  30  DT  F "O4'"  1 
ATOM   5019 C  "C3'"  . DT  F 3 14 ? 18.66800  27.15600  21.18900  1.000 63.69544  ?  30  DT  F "C3'"  1 
ATOM   5020 O  "O3'"  . DT  F 3 14 ? 18.00400  26.99500  19.97400  1.000 68.56439  ?  30  DT  F "O3'"  1 
ATOM   5021 C  "C2'"  . DT  F 3 14 ? 17.81600  27.83400  22.27500  1.000 63.21362  ?  30  DT  F "C2'"  1 
ATOM   5022 C  "C1'"  . DT  F 3 14 ? 17.48600  26.68700  23.20000  1.000 61.06615  ?  30  DT  F "C1'"  1 
ATOM   5023 N  N1     . DT  F 3 14 ? 17.32300  27.00600  24.60900  1.000 63.88125  ?  30  DT  F N1     1 
ATOM   5024 C  C2     . DT  F 3 14 ? 16.05800  27.04300  25.14200  1.000 60.19086  ?  30  DT  F C2     1 
ATOM   5025 O  O2     . DT  F 3 14 ? 15.04700  26.91400  24.48600  1.000 62.59612  ?  30  DT  F O2     1 
ATOM   5026 N  N3     . DT  F 3 14 ? 16.00800  27.28900  26.47000  1.000 59.82298  ?  30  DT  F N3     1 
ATOM   5027 C  C4     . DT  F 3 14 ? 17.06700  27.46400  27.32000  1.000 60.10530  ?  30  DT  F C4     1 
ATOM   5028 O  O4     . DT  F 3 14 ? 16.89500  27.66500  28.49800  1.000 60.12980  ?  30  DT  F O4     1 
ATOM   5029 C  C5     . DT  F 3 14 ? 18.37500  27.37300  26.70800  1.000 62.14520  ?  30  DT  F C5     1 
ATOM   5030 C  C7     . DT  F 3 14 ? 19.61100  27.53200  27.51500  1.000 64.06789  ?  30  DT  F C7     1 
ATOM   5031 C  C6     . DT  F 3 14 ? 18.43400  27.13700  25.40000  1.000 64.52059  ?  30  DT  F C6     1 
ATOM   5032 H  "H5'"  . DT  F 3 14 ? 20.46400  24.42900  21.93300  1.000 78.16240  ?  30  DT  F "H5'"  1 
ATOM   5033 H  "H5''" . DT  F 3 14 ? 20.57500  25.27800  20.60300  1.000 78.16240  ?  30  DT  F "H5''" 1 
ATOM   5034 H  "H4'"  . DT  F 3 14 ? 18.36700  25.13300  21.26200  1.000 74.43780  ?  30  DT  F "H4'"  1 
ATOM   5035 H  "H3'"  . DT  F 3 14 ? 19.49800  27.64000  21.05900  1.000 76.43453  ?  30  DT  F "H3'"  1 
ATOM   5036 H  "H2'"  . DT  F 3 14 ? 18.32700  28.51600  22.73900  1.000 75.85635  ?  30  DT  F "H2'"  1 
ATOM   5037 H  "H2''" . DT  F 3 14 ? 17.01000  28.20600  21.89000  1.000 75.85635  ?  30  DT  F "H2''" 1 
ATOM   5038 H  "H1'"  . DT  F 3 14 ? 16.68800  26.23900  22.87900  1.000 73.27938  ?  30  DT  F "H1'"  1 
ATOM   5039 H  H3     . DT  F 3 14 ? 15.22400  27.34200  26.82000  1.000 71.78757  ?  30  DT  F H3     1 
ATOM   5040 H  H71    . DT  F 3 14 ? 20.37900  27.26700  26.98600  1.000 76.88147  ?  30  DT  F H71    1 
ATOM   5041 H  H72    . DT  F 3 14 ? 19.70700  28.46000  27.78000  1.000 76.88147  ?  30  DT  F H72    1 
ATOM   5042 H  H73    . DT  F 3 14 ? 19.55400  26.97400  28.30600  1.000 76.88147  ?  30  DT  F H73    1 
ATOM   5043 H  H6     . DT  F 3 14 ? 19.27100  27.07200  25.00000  1.000 77.42471  ?  30  DT  F H6     1 
ATOM   5044 P  P      . DA  F 3 15 ? 17.68300  28.22900  19.02500  1.000 72.29736  ?  31  DA  F P      1 
ATOM   5045 O  OP1    . DA  F 3 15 ? 17.65100  27.55200  17.70900  1.000 75.77770  ?  31  DA  F OP1    1 
ATOM   5046 O  OP2    . DA  F 3 15 ? 18.57900  29.36300  19.34600  1.000 72.37890  -1 31  DA  F OP2    1 
ATOM   5047 O  "O5'"  . DA  F 3 15 ? 16.20600  28.66300  19.42700  1.000 65.19673  ?  31  DA  F "O5'"  1 
ATOM   5048 C  "C5'"  . DA  F 3 15 ? 15.15900  27.71800  19.32800  1.000 69.87257  ?  31  DA  F "C5'"  1 
ATOM   5049 C  "C4'"  . DA  F 3 15 ? 13.91500  28.20800  20.03200  1.000 66.65391  ?  31  DA  F "C4'"  1 
ATOM   5050 O  "O4'"  . DA  F 3 15 ? 14.19000  28.34300  21.44000  1.000 68.77292  ?  31  DA  F "O4'"  1 
ATOM   5051 C  "C3'"  . DA  F 3 15 ? 13.40300  29.57000  19.56200  1.000 70.35002  ?  31  DA  F "C3'"  1 
ATOM   5052 O  "O3'"  . DA  F 3 15 ? 12.04100  29.43800  19.16700  1.000 69.39036  ?  31  DA  F "O3'"  1 
ATOM   5053 C  "C2'"  . DA  F 3 15 ? 13.59600  30.50100  20.77400  1.000 68.11006  ?  31  DA  F "C2'"  1 
ATOM   5054 C  "C1'"  . DA  F 3 15 ? 13.59700  29.52900  21.93300  1.000 68.09659  ?  31  DA  F "C1'"  1 
ATOM   5055 N  N9     . DA  F 3 15 ? 14.36600  29.92400  23.10400  1.000 67.48541  ?  31  DA  F N9     1 
ATOM   5056 C  C8     . DA  F 3 15 ? 15.71000  30.08900  23.18300  1.000 66.06142  ?  31  DA  F C8     1 
ATOM   5057 N  N7     . DA  F 3 15 ? 16.13700  30.39400  24.38000  1.000 64.34230  ?  31  DA  F N7     1 
ATOM   5058 C  C5     . DA  F 3 15 ? 14.99500  30.40300  25.13900  1.000 64.56611  ?  31  DA  F C5     1 
ATOM   5059 C  C6     . DA  F 3 15 ? 14.77900  30.64800  26.49200  1.000 65.18564  ?  31  DA  F C6     1 
ATOM   5060 N  N6     . DA  F 3 15 ? 15.75500  30.96100  27.34000  1.000 67.25186  ?  31  DA  F N6     1 
ATOM   5061 N  N1     . DA  F 3 15 ? 13.51700  30.57400  26.94100  1.000 65.43080  ?  31  DA  F N1     1 
ATOM   5062 C  C2     . DA  F 3 15 ? 12.54400  30.27100  26.07800  1.000 68.49107  ?  31  DA  F C2     1 
ATOM   5063 N  N3     . DA  F 3 15 ? 12.63100  30.01400  24.78100  1.000 67.43451  ?  31  DA  F N3     1 
ATOM   5064 C  C4     . DA  F 3 15 ? 13.89300  30.10300  24.37300  1.000 64.02490  ?  31  DA  F C4     1 
ATOM   5065 H  "H5'"  . DA  F 3 15 ? 15.44500  26.88300  19.73100  1.000 83.84708  ?  31  DA  F "H5'"  1 
ATOM   5066 H  "H5''" . DA  F 3 15 ? 14.95600  27.56600  18.39200  1.000 83.84708  ?  31  DA  F "H5''" 1 
ATOM   5067 H  "H4'"  . DA  F 3 15 ? 13.21100  27.55200  19.91300  1.000 79.98469  ?  31  DA  F "H4'"  1 
ATOM   5068 H  "H3'"  . DA  F 3 15 ? 13.93600  29.88400  18.81500  1.000 84.42003  ?  31  DA  F "H3'"  1 
ATOM   5069 H  "H2'"  . DA  F 3 15 ? 14.44300  30.97000  20.71600  1.000 81.73207  ?  31  DA  F "H2'"  1 
ATOM   5070 H  "H2''" . DA  F 3 15 ? 12.85800  31.12600  20.84900  1.000 81.73207  ?  31  DA  F "H2''" 1 
ATOM   5071 H  "H1'"  . DA  F 3 15 ? 12.68200  29.34400  22.19700  1.000 81.71591  ?  31  DA  F "H1'"  1 
ATOM   5072 H  H8     . DA  F 3 15 ? 16.27300  30.01600  22.44700  1.000 79.27371  ?  31  DA  F H8     1 
ATOM   5073 H  H61    . DA  F 3 15 ? 15.57400  31.11400  28.16700  1.000 80.70223  ?  31  DA  F H61    1 
ATOM   5074 H  H62    . DA  F 3 15 ? 16.56700  31.01100  27.06100  1.000 80.70223  ?  31  DA  F H62    1 
ATOM   5075 H  H2     . DA  F 3 15 ? 11.68800  30.23000  26.43800  1.000 82.18929  ?  31  DA  F H2     1 
ATOM   5076 P  P      . DT  F 3 16 ? 11.27200  30.64200  18.44300  1.000 78.30900  ?  32  DT  F P      1 
ATOM   5077 O  OP1    . DT  F 3 16 ? 10.45700  30.01000  17.38100  1.000 77.68361  ?  32  DT  F OP1    1 
ATOM   5078 O  OP2    . DT  F 3 16 ? 12.26400  31.66500  18.06300  1.000 76.42990  -1 32  DT  F OP2    1 
ATOM   5079 O  "O5'"  . DT  F 3 16 ? 10.34600  31.25500  19.60100  1.000 75.24639  ?  32  DT  F "O5'"  1 
ATOM   5080 C  "C5'"  . DT  F 3 16 ? 9.68300   30.37100  20.51100  1.000 77.75386  ?  32  DT  F "C5'"  1 
ATOM   5081 C  "C4'"  . DT  F 3 16 ? 8.93800   31.13200  21.60000  1.000 79.87708  ?  32  DT  F "C4'"  1 
ATOM   5082 O  "O4'"  . DT  F 3 16 ? 9.81500   31.33100  22.74800  1.000 79.73130  ?  32  DT  F "O4'"  1 
ATOM   5083 C  "C3'"  . DT  F 3 16 ? 8.44800   32.52600  21.19700  1.000 78.90800  ?  32  DT  F "C3'"  1 
ATOM   5084 O  "O3'"  . DT  F 3 16 ? 7.11200   32.74100  21.65900  1.000 85.44781  ?  32  DT  F "O3'"  1 
ATOM   5085 C  "C2'"  . DT  F 3 16 ? 9.44900   33.46500  21.87100  1.000 80.18658  ?  32  DT  F "C2'"  1 
ATOM   5086 C  "C1'"  . DT  F 3 16 ? 9.76000   32.69600  23.14800  1.000 79.58948  ?  32  DT  F "C1'"  1 
ATOM   5087 N  N1     . DT  F 3 16 ? 11.04600  33.06700  23.81300  1.000 70.89329  ?  32  DT  F N1     1 
ATOM   5088 C  C2     . DT  F 3 16 ? 11.05400  33.26100  25.17300  1.000 71.71910  ?  32  DT  F C2     1 
ATOM   5089 O  O2     . DT  F 3 16 ? 10.05700  33.15200  25.87100  1.000 72.17465  ?  32  DT  F O2     1 
ATOM   5090 N  N3     . DT  F 3 16 ? 12.28100  33.58300  25.69200  1.000 73.79723  ?  32  DT  F N3     1 
ATOM   5091 C  C4     . DT  F 3 16 ? 13.47300  33.72500  24.99600  1.000 72.21011  ?  32  DT  F C4     1 
ATOM   5092 O  O4     . DT  F 3 16 ? 14.52800  34.01900  25.54900  1.000 71.56959  ?  32  DT  F O4     1 
ATOM   5093 C  C5     . DT  F 3 16 ? 13.38500  33.51100  23.57400  1.000 68.63859  ?  32  DT  F C5     1 
ATOM   5094 C  C7     . DT  F 3 16 ? 14.60800  33.63100  22.71400  1.000 67.47785  ?  32  DT  F C7     1 
ATOM   5095 C  C6     . DT  F 3 16 ? 12.19300  33.19200  23.06000  1.000 70.44731  ?  32  DT  F C6     1 
ATOM   5096 H  "H5'"  . DT  F 3 16 ? 10.34200  29.79200  20.92500  1.000 93.30463  ?  32  DT  F "H5'"  1 
ATOM   5097 H  "H5''" . DT  F 3 16 ? 9.05000   29.82600  20.01700  1.000 93.30463  ?  32  DT  F "H5''" 1 
ATOM   5098 H  "H4'"  . DT  F 3 16 ? 8.17400   30.60400  21.88000  1.000 95.85249  ?  32  DT  F "H4'"  1 
ATOM   5099 H  "H3'"  . DT  F 3 16 ? 8.49000   32.62900  20.23400  1.000 94.68961  ?  32  DT  F "H3'"  1 
ATOM   5100 H  "HO3'" . DT  F 3 16 ? 6.49800   32.90200  21.10900  1.000 102.53737 ?  32  DT  F "HO3'" 1 
ATOM   5101 H  "H2'"  . DT  F 3 16 ? 10.24200  33.57400  21.32500  1.000 96.22389  ?  32  DT  F "H2'"  1 
ATOM   5102 H  "H2''" . DT  F 3 16 ? 9.04100   34.32200  22.07200  1.000 96.22389  ?  32  DT  F "H2''" 1 
ATOM   5103 H  "H1'"  . DT  F 3 16 ? 9.03000   32.81400  23.77500  1.000 95.50738  ?  32  DT  F "H1'"  1 
ATOM   5104 H  H3     . DT  F 3 16 ? 12.31600  33.71100  26.54100  1.000 88.55667  ?  32  DT  F H3     1 
ATOM   5105 H  H71    . DT  F 3 16 ? 14.77100  32.78700  22.26400  1.000 80.97342  ?  32  DT  F H71    1 
ATOM   5106 H  H72    . DT  F 3 16 ? 14.47100  34.32800  22.05300  1.000 80.97342  ?  32  DT  F H72    1 
ATOM   5107 H  H73    . DT  F 3 16 ? 15.37200  33.85500  23.26700  1.000 80.97342  ?  32  DT  F H73    1 
ATOM   5108 H  H6     . DT  F 3 16 ? 12.13500  33.04600  22.14300  1.000 84.53678  ?  32  DT  F H6     1 
HETATM 5109 ZN ZN     . ZN  G 4 .  ? -12.50300 20.57500  23.95700  1.000 115.83787 2  301 ZN  C ZN     1 
HETATM 5110 O  O      . HOH H 5 .  ? 35.16600  19.33200  24.80100  1.000 69.39651  ?  301 HOH A O      1 
HETATM 5111 O  O      . HOH H 5 .  ? 29.96000  10.88400  20.91500  1.000 43.01084  ?  302 HOH A O      1 
HETATM 5112 O  O      . HOH H 5 .  ? 24.49700  9.69900   10.22300  1.000 39.82160  ?  303 HOH A O      1 
HETATM 5113 O  O      . HOH H 5 .  ? 36.26500  2.75700   19.53200  1.000 65.13833  ?  304 HOH A O      1 
HETATM 5114 O  O      . HOH H 5 .  ? 33.03700  3.32400   -5.05100  1.000 42.13054  ?  305 HOH A O      1 
HETATM 5115 O  O      . HOH H 5 .  ? 32.04600  8.05100   -9.25000  1.000 48.01738  ?  306 HOH A O      1 
HETATM 5116 O  O      . HOH H 5 .  ? 31.15200  14.14000  -4.13600  1.000 37.62026  ?  307 HOH A O      1 
HETATM 5117 O  O      . HOH H 5 .  ? 26.31800  3.76300   18.28300  1.000 52.95858  ?  308 HOH A O      1 
HETATM 5118 O  O      . HOH H 5 .  ? 37.44900  17.11900  -2.04400  1.000 48.54127  ?  309 HOH A O      1 
HETATM 5119 O  O      . HOH H 5 .  ? 20.86100  3.08700   1.66700   1.000 43.16376  ?  310 HOH A O      1 
HETATM 5120 O  O      . HOH H 5 .  ? 37.70700  0.02200   -6.10000  1.000 55.05800  ?  311 HOH A O      1 
HETATM 5121 O  O      . HOH H 5 .  ? 23.75700  19.15100  8.32500   1.000 52.15382  ?  312 HOH A O      1 
HETATM 5122 O  O      . HOH H 5 .  ? 48.71300  8.57100   10.38400  1.000 50.25101  ?  313 HOH A O      1 
HETATM 5123 O  O      . HOH H 5 .  ? 28.47800  10.72600  -6.80800  1.000 43.96250  ?  314 HOH A O      1 
HETATM 5124 O  O      . HOH H 5 .  ? 24.38300  13.95500  4.76000   1.000 39.45203  ?  315 HOH A O      1 
HETATM 5125 O  O      . HOH H 5 .  ? 36.98600  4.83000   -5.19900  1.000 40.70712  ?  316 HOH A O      1 
HETATM 5126 O  O      . HOH H 5 .  ? 27.92700  4.46500   -0.31300  1.000 28.80585  ?  317 HOH A O      1 
HETATM 5127 O  O      . HOH H 5 .  ? 36.84700  2.54700   -6.29400  1.000 49.42622  ?  318 HOH A O      1 
HETATM 5128 O  O      . HOH H 5 .  ? 23.47900  19.70000  15.56800  1.000 49.09933  ?  319 HOH A O      1 
HETATM 5129 O  O      . HOH H 5 .  ? 36.29800  11.26200  -5.13100  1.000 48.44839  ?  320 HOH A O      1 
HETATM 5130 O  O      . HOH H 5 .  ? 17.92300  4.49800   3.26000   1.000 45.12435  ?  321 HOH A O      1 
HETATM 5131 O  O      . HOH H 5 .  ? 35.19191  22.09100  25.90977  0.50  61.61078  ?  322 HOH A O      1 
HETATM 5132 O  O      . HOH I 5 .  ? 12.10300  2.02300   -0.60700  1.000 62.10899  ?  101 HOH B O      1 
HETATM 5133 O  O      . HOH I 5 .  ? 23.11100  11.11000  -1.81000  1.000 30.84217  ?  102 HOH B O      1 
HETATM 5134 O  O      . HOH I 5 .  ? 22.99200  -7.73700  -7.82400  1.000 63.98206  ?  103 HOH B O      1 
HETATM 5135 O  O      . HOH I 5 .  ? 21.04500  13.49700  8.19300   1.000 42.32410  ?  104 HOH B O      1 
HETATM 5136 O  O      . HOH I 5 .  ? 17.95100  -4.53300  -3.30700  1.000 56.31195  ?  105 HOH B O      1 
HETATM 5137 O  O      . HOH I 5 .  ? 26.62800  -13.10300 -3.76600  1.000 56.50770  ?  106 HOH B O      1 
HETATM 5138 O  O      . HOH I 5 .  ? 16.80200  2.16200   -8.10600  1.000 54.11728  ?  107 HOH B O      1 
HETATM 5139 O  O      . HOH I 5 .  ? 16.30100  -1.05900  -1.05500  1.000 43.38734  ?  108 HOH B O      1 
HETATM 5140 O  O      . HOH I 5 .  ? 28.75000  -15.70900 -0.94700  1.000 60.22560  ?  109 HOH B O      1 
HETATM 5141 O  O      . HOH I 5 .  ? 20.03600  20.46000  3.70000   1.000 42.92306  ?  110 HOH B O      1 
HETATM 5142 O  O      . HOH I 5 .  ? 16.26300  -3.48400  -1.66100  1.000 50.47861  ?  111 HOH B O      1 
HETATM 5143 O  O      . HOH J 5 .  ? 8.44200   7.31600   7.26200   1.000 56.71372  ?  401 HOH C O      1 
HETATM 5144 O  O      . HOH J 5 .  ? -13.96900 21.81300  22.61800  1.000 72.24336  ?  402 HOH C O      1 
HETATM 5145 O  O      . HOH J 5 .  ? 10.56300  13.46600  15.12400  1.000 39.08230  ?  403 HOH C O      1 
HETATM 5146 O  O      . HOH J 5 .  ? -1.86700  21.04400  28.37700  1.000 49.36294  ?  404 HOH C O      1 
HETATM 5147 O  O      . HOH J 5 .  ? -12.252   25.072    23.305    1.000 73.97902  ?  405 HOH C O      1 
HETATM 5148 O  O      . HOH J 5 .  ? 3.46500   11.30600  35.12300  1.000 45.51204  ?  406 HOH C O      1 
HETATM 5149 O  O      . HOH J 5 .  ? -7.78700  6.55500   23.42200  1.000 41.48376  ?  407 HOH C O      1 
HETATM 5150 O  O      . HOH J 5 .  ? 0.43100   22.85800  1.28300   1.000 74.12787  ?  408 HOH C O      1 
HETATM 5151 O  O      . HOH J 5 .  ? -8.28900  17.09400  12.66700  1.000 47.15944  ?  409 HOH C O      1 
HETATM 5152 O  O      . HOH J 5 .  ? -1.15000  14.42100  30.91700  1.000 41.46873  ?  410 HOH C O      1 
HETATM 5153 O  O      . HOH J 5 .  ? 6.88700   14.22400  32.58100  1.000 36.59923  ?  411 HOH C O      1 
HETATM 5154 O  O      . HOH J 5 .  ? -1.60600  8.39700   30.80300  1.000 34.88137  ?  412 HOH C O      1 
HETATM 5155 O  O      . HOH J 5 .  ? -12.38800 12.95400  22.46900  1.000 51.88345  ?  413 HOH C O      1 
HETATM 5156 O  O      . HOH J 5 .  ? -5.96000  14.56900  34.36000  1.000 34.85847  ?  414 HOH C O      1 
HETATM 5157 O  O      . HOH J 5 .  ? 0.27300   1.38500   14.73300  1.000 51.52835  ?  415 HOH C O      1 
HETATM 5158 O  O      . HOH J 5 .  ? 7.36200   7.94700   25.91200  1.000 33.60978  ?  416 HOH C O      1 
HETATM 5159 O  O      . HOH J 5 .  ? -13.682   12.481    15.994    1.000 51.92145  ?  417 HOH C O      1 
HETATM 5160 O  O      . HOH J 5 .  ? -7.53400  16.76100  15.17500  1.000 39.55126  ?  418 HOH C O      1 
HETATM 5161 O  O      . HOH J 5 .  ? 11.50600  22.96700  17.19700  1.000 53.77749  ?  419 HOH C O      1 
HETATM 5162 O  O      . HOH J 5 .  ? 10.54100  17.54400  20.74600  1.000 46.46886  ?  420 HOH C O      1 
HETATM 5163 O  O      . HOH J 5 .  ? -4.57500  13.11500  5.77400   1.000 52.75992  ?  421 HOH C O      1 
HETATM 5164 O  O      . HOH J 5 .  ? 0.52800   2.02700   12.38200  1.000 57.88226  ?  422 HOH C O      1 
HETATM 5165 O  O      . HOH J 5 .  ? -1.34800  24.00600  0.88100   1.000 72.52559  ?  423 HOH C O      1 
HETATM 5166 O  O      . HOH J 5 .  ? -9.747    19.378    26.802    1.000 79.30498  ?  424 HOH C O      1 
HETATM 5167 O  O      . HOH J 5 .  ? -14.58900 19.90700  23.32600  1.000 53.75867  ?  425 HOH C O      1 
HETATM 5168 O  O      . HOH J 5 .  ? 0.00000   25.65100  0.00000   0.50  64.30601  ?  426 HOH C O      1 
HETATM 5169 O  O      . HOH K 5 .  ? 18.87600  2.83100   26.02500  1.000 49.73933  ?  101 HOH D O      1 
HETATM 5170 O  O      . HOH K 5 .  ? 16.97700  0.44800   37.90500  1.000 63.92081  ?  102 HOH D O      1 
HETATM 5171 O  O      . HOH K 5 .  ? 6.21900   -12.17200 26.99200  1.000 70.36531  ?  103 HOH D O      1 
HETATM 5172 O  O      . HOH K 5 .  ? 10.34600  22.40900  30.93500  1.000 59.26422  ?  104 HOH D O      1 
HETATM 5173 O  O      . HOH K 5 .  ? 18.14000  -0.44200  27.89900  1.000 49.78105  ?  105 HOH D O      1 
HETATM 5174 O  O      . HOH L 5 .  ? 23.13700  14.51000  -6.97600  1.000 43.58783  ?  101 HOH E O      1 
HETATM 5175 O  O      . HOH L 5 .  ? 30.11900  -1.17300  -6.86800  1.000 50.70956  ?  102 HOH E O      1 
HETATM 5176 O  O      . HOH L 5 .  ? 20.46200  -3.13200  4.17900   1.000 44.26016  ?  103 HOH E O      1 
HETATM 5177 O  O      . HOH L 5 .  ? 28.59900  6.05300   -9.37300  1.000 36.71901  ?  104 HOH E O      1 
HETATM 5178 O  O      . HOH L 5 .  ? 21.74000  18.19100  -7.63700  1.000 42.53874  ?  105 HOH E O      1 
HETATM 5179 O  O      . HOH L 5 .  ? 24.70900  24.86600  1.51900   1.000 56.82983  ?  106 HOH E O      1 
HETATM 5180 O  O      . HOH L 5 .  ? 31.58100  -1.50000  4.54500   1.000 49.56236  ?  107 HOH E O      1 
HETATM 5181 O  O      . HOH L 5 .  ? 18.47800  19.14700  1.75700   1.000 32.21070  ?  108 HOH E O      1 
HETATM 5182 O  O      . HOH L 5 .  ? 17.52500  24.83700  -5.58600  1.000 52.34175  ?  109 HOH E O      1 
HETATM 5183 O  O      . HOH L 5 .  ? 24.44600  9.20000   -3.47100  1.000 28.97577  ?  110 HOH E O      1 
HETATM 5184 O  O      . HOH L 5 .  ? 18.87300  16.25900  -11.64700 1.000 41.61561  ?  111 HOH E O      1 
HETATM 5185 O  O      . HOH L 5 .  ? 19.23100  21.80800  -7.53000  1.000 45.37263  ?  112 HOH E O      1 
HETATM 5186 O  O      . HOH L 5 .  ? 24.57300  -0.54700  -6.71300  1.000 43.66951  ?  113 HOH E O      1 
HETATM 5187 O  O      . HOH L 5 .  ? 25.21500  10.49300  -5.99100  1.000 30.86027  ?  114 HOH E O      1 
HETATM 5188 O  O      . HOH L 5 .  ? 22.08100  21.81500  2.51300   1.000 48.42431  ?  115 HOH E O      1 
HETATM 5189 O  O      . HOH L 5 .  ? 15.29200  19.89300  -9.13200  1.000 47.17737  ?  116 HOH E O      1 
HETATM 5190 O  O      . HOH L 5 .  ? 22.32300  -2.29700  7.95500   1.000 53.79895  ?  117 HOH E O      1 
HETATM 5191 O  O      . HOH L 5 .  ? 22.263    13.713    -16.021   1.000 42.70123  ?  118 HOH E O      1 
HETATM 5192 O  O      . HOH L 5 .  ? 14.54700  24.94500  -5.69800  1.000 49.79183  ?  119 HOH E O      1 
HETATM 5193 O  O      . HOH M 5 .  ? 14.64800  0.51500   21.11200  1.000 46.48639  ?  101 HOH F O      1 
HETATM 5194 O  O      . HOH M 5 .  ? 6.82400   9.67500   34.64600  1.000 45.33245  ?  102 HOH F O      1 
HETATM 5195 O  O      . HOH M 5 .  ? 25.37800  17.38100  33.61800  1.000 81.28448  ?  103 HOH F O      1 
HETATM 5196 O  O      . HOH M 5 .  ? 3.69500   2.06200   21.10100  1.000 43.86758  ?  104 HOH F O      1 
HETATM 5197 O  O      . HOH M 5 .  ? 7.61900   0.57500   26.50900  1.000 48.64965  ?  105 HOH F O      1 
HETATM 5198 O  O      . HOH M 5 .  ? 11.04100  12.43600  28.80600  1.000 35.69751  ?  106 HOH F O      1 
HETATM 5199 O  O      . HOH M 5 .  ? 27.30900  20.63200  29.01800  1.000 70.35389  ?  107 HOH F O      1 
HETATM 5200 O  O      . HOH M 5 .  ? 2.36000   6.72900   30.25700  1.000 38.39303  ?  108 HOH F O      1 
HETATM 5201 O  O      . HOH M 5 .  ? 12.09200  1.53500   17.14600  1.000 47.18456  ?  109 HOH F O      1 
HETATM 5202 O  O      . HOH M 5 .  ? 17.41000  22.40100  23.06200  1.000 52.67212  ?  110 HOH F O      1 
HETATM 5203 O  O      . HOH M 5 .  ? 10.18600  2.31900   31.68400  1.000 46.29028  ?  111 HOH F O      1 
# 
