data_9CL0
# 
_entry.id   9CL0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CL0         pdb_00009cl0 10.2210/pdb9cl0/pdb 
WWPDB D_1000284341 ?            ?                   
EMDB  EMD-45657    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-18 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CL0 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of human XPR1 in presence of inorganic phosphate and phytic acid' 
_pdbx_database_related.db_id          EMD-45657 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhaow@bcm.edu 
_pdbx_contact_author.name_first         Zhao 
_pdbx_contact_author.name_last          Wang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4897-9986 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wang, Z.' 1 ? 
'Wu, H.'   2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                4519 
_citation.page_last                 4519 
_citation.title                     
'The identification of XPR1 as a voltage- and phosphate-activated phosphate-permeable ion channel.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-59678-2 
_citation.pdbx_database_id_PubMed   40374661 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wu, H.'         1 ?                   
primary 'Sun, L.'        2 0000-0002-7817-5121 
primary 'Huo, T.'        3 ?                   
primary 'Wensel, T.G.'   4 0000-0003-3518-9352 
primary 'Horrigan, F.T.' 5 0000-0001-6703-9581 
primary 'Wang, Z.'       6 0000-0003-4897-9986 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Solute carrier family 53 member 1' 
_entity.formula_weight             84991.484 
_entity.pdbx_number_of_molecules   2 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Phosphate exporter SLC53A1,Protein SYG1 homolog,Xenotropic and polytropic murine leukemia virus receptor X3,X-receptor,Xenotropic and polytropic retrovirus receptor 1
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTENLYFQGHHHHHHHHSGAAAWSHP
QFEK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTENLYFQGHHHHHHHHSGAAAWSHP
QFEK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   PHE n 
1 4   ALA n 
1 5   GLU n 
1 6   HIS n 
1 7   LEU n 
1 8   SER n 
1 9   ALA n 
1 10  HIS n 
1 11  ILE n 
1 12  THR n 
1 13  PRO n 
1 14  GLU n 
1 15  TRP n 
1 16  ARG n 
1 17  LYS n 
1 18  GLN n 
1 19  TYR n 
1 20  ILE n 
1 21  GLN n 
1 22  TYR n 
1 23  GLU n 
1 24  ALA n 
1 25  PHE n 
1 26  LYS n 
1 27  ASP n 
1 28  MET n 
1 29  LEU n 
1 30  TYR n 
1 31  SER n 
1 32  ALA n 
1 33  GLN n 
1 34  ASP n 
1 35  GLN n 
1 36  ALA n 
1 37  PRO n 
1 38  SER n 
1 39  VAL n 
1 40  GLU n 
1 41  VAL n 
1 42  THR n 
1 43  ASP n 
1 44  GLU n 
1 45  ASP n 
1 46  THR n 
1 47  VAL n 
1 48  LYS n 
1 49  ARG n 
1 50  TYR n 
1 51  PHE n 
1 52  ALA n 
1 53  LYS n 
1 54  PHE n 
1 55  GLU n 
1 56  GLU n 
1 57  LYS n 
1 58  PHE n 
1 59  PHE n 
1 60  GLN n 
1 61  THR n 
1 62  CYS n 
1 63  GLU n 
1 64  LYS n 
1 65  GLU n 
1 66  LEU n 
1 67  ALA n 
1 68  LYS n 
1 69  ILE n 
1 70  ASN n 
1 71  THR n 
1 72  PHE n 
1 73  TYR n 
1 74  SER n 
1 75  GLU n 
1 76  LYS n 
1 77  LEU n 
1 78  ALA n 
1 79  GLU n 
1 80  ALA n 
1 81  GLN n 
1 82  ARG n 
1 83  ARG n 
1 84  PHE n 
1 85  ALA n 
1 86  THR n 
1 87  LEU n 
1 88  GLN n 
1 89  ASN n 
1 90  GLU n 
1 91  LEU n 
1 92  GLN n 
1 93  SER n 
1 94  SER n 
1 95  LEU n 
1 96  ASP n 
1 97  ALA n 
1 98  GLN n 
1 99  LYS n 
1 100 GLU n 
1 101 SER n 
1 102 THR n 
1 103 GLY n 
1 104 VAL n 
1 105 THR n 
1 106 THR n 
1 107 LEU n 
1 108 ARG n 
1 109 GLN n 
1 110 ARG n 
1 111 ARG n 
1 112 LYS n 
1 113 PRO n 
1 114 VAL n 
1 115 PHE n 
1 116 HIS n 
1 117 LEU n 
1 118 SER n 
1 119 HIS n 
1 120 GLU n 
1 121 GLU n 
1 122 ARG n 
1 123 VAL n 
1 124 GLN n 
1 125 HIS n 
1 126 ARG n 
1 127 ASN n 
1 128 ILE n 
1 129 LYS n 
1 130 ASP n 
1 131 LEU n 
1 132 LYS n 
1 133 LEU n 
1 134 ALA n 
1 135 PHE n 
1 136 SER n 
1 137 GLU n 
1 138 PHE n 
1 139 TYR n 
1 140 LEU n 
1 141 SER n 
1 142 LEU n 
1 143 ILE n 
1 144 LEU n 
1 145 LEU n 
1 146 GLN n 
1 147 ASN n 
1 148 TYR n 
1 149 GLN n 
1 150 ASN n 
1 151 LEU n 
1 152 ASN n 
1 153 PHE n 
1 154 THR n 
1 155 GLY n 
1 156 PHE n 
1 157 ARG n 
1 158 LYS n 
1 159 ILE n 
1 160 LEU n 
1 161 LYS n 
1 162 LYS n 
1 163 HIS n 
1 164 ASP n 
1 165 LYS n 
1 166 ILE n 
1 167 LEU n 
1 168 GLU n 
1 169 THR n 
1 170 SER n 
1 171 ARG n 
1 172 GLY n 
1 173 ALA n 
1 174 ASP n 
1 175 TRP n 
1 176 ARG n 
1 177 VAL n 
1 178 ALA n 
1 179 HIS n 
1 180 VAL n 
1 181 GLU n 
1 182 VAL n 
1 183 ALA n 
1 184 PRO n 
1 185 PHE n 
1 186 TYR n 
1 187 THR n 
1 188 CYS n 
1 189 LYS n 
1 190 LYS n 
1 191 ILE n 
1 192 ASN n 
1 193 GLN n 
1 194 LEU n 
1 195 ILE n 
1 196 SER n 
1 197 GLU n 
1 198 THR n 
1 199 GLU n 
1 200 ALA n 
1 201 VAL n 
1 202 VAL n 
1 203 THR n 
1 204 ASN n 
1 205 GLU n 
1 206 LEU n 
1 207 GLU n 
1 208 ASP n 
1 209 GLY n 
1 210 ASP n 
1 211 ARG n 
1 212 GLN n 
1 213 LYS n 
1 214 ALA n 
1 215 MET n 
1 216 LYS n 
1 217 ARG n 
1 218 LEU n 
1 219 ARG n 
1 220 VAL n 
1 221 PRO n 
1 222 PRO n 
1 223 LEU n 
1 224 GLY n 
1 225 ALA n 
1 226 ALA n 
1 227 GLN n 
1 228 PRO n 
1 229 ALA n 
1 230 PRO n 
1 231 ALA n 
1 232 TRP n 
1 233 THR n 
1 234 THR n 
1 235 PHE n 
1 236 ARG n 
1 237 VAL n 
1 238 GLY n 
1 239 LEU n 
1 240 PHE n 
1 241 CYS n 
1 242 GLY n 
1 243 ILE n 
1 244 PHE n 
1 245 ILE n 
1 246 VAL n 
1 247 LEU n 
1 248 ASN n 
1 249 ILE n 
1 250 THR n 
1 251 LEU n 
1 252 VAL n 
1 253 LEU n 
1 254 ALA n 
1 255 ALA n 
1 256 VAL n 
1 257 PHE n 
1 258 LYS n 
1 259 LEU n 
1 260 GLU n 
1 261 THR n 
1 262 ASP n 
1 263 ARG n 
1 264 SER n 
1 265 ILE n 
1 266 TRP n 
1 267 PRO n 
1 268 LEU n 
1 269 ILE n 
1 270 ARG n 
1 271 ILE n 
1 272 TYR n 
1 273 ARG n 
1 274 GLY n 
1 275 GLY n 
1 276 PHE n 
1 277 LEU n 
1 278 LEU n 
1 279 ILE n 
1 280 GLU n 
1 281 PHE n 
1 282 LEU n 
1 283 PHE n 
1 284 LEU n 
1 285 LEU n 
1 286 GLY n 
1 287 ILE n 
1 288 ASN n 
1 289 THR n 
1 290 TYR n 
1 291 GLY n 
1 292 TRP n 
1 293 ARG n 
1 294 GLN n 
1 295 ALA n 
1 296 GLY n 
1 297 VAL n 
1 298 ASN n 
1 299 HIS n 
1 300 VAL n 
1 301 LEU n 
1 302 ILE n 
1 303 PHE n 
1 304 GLU n 
1 305 LEU n 
1 306 ASN n 
1 307 PRO n 
1 308 ARG n 
1 309 SER n 
1 310 ASN n 
1 311 LEU n 
1 312 SER n 
1 313 HIS n 
1 314 GLN n 
1 315 HIS n 
1 316 LEU n 
1 317 PHE n 
1 318 GLU n 
1 319 ILE n 
1 320 ALA n 
1 321 GLY n 
1 322 PHE n 
1 323 LEU n 
1 324 GLY n 
1 325 ILE n 
1 326 LEU n 
1 327 TRP n 
1 328 CYS n 
1 329 LEU n 
1 330 SER n 
1 331 LEU n 
1 332 LEU n 
1 333 ALA n 
1 334 CYS n 
1 335 PHE n 
1 336 PHE n 
1 337 ALA n 
1 338 PRO n 
1 339 ILE n 
1 340 SER n 
1 341 VAL n 
1 342 ILE n 
1 343 PRO n 
1 344 THR n 
1 345 TYR n 
1 346 VAL n 
1 347 TYR n 
1 348 PRO n 
1 349 LEU n 
1 350 ALA n 
1 351 LEU n 
1 352 TYR n 
1 353 GLY n 
1 354 PHE n 
1 355 MET n 
1 356 VAL n 
1 357 PHE n 
1 358 PHE n 
1 359 LEU n 
1 360 ILE n 
1 361 ASN n 
1 362 PRO n 
1 363 THR n 
1 364 LYS n 
1 365 THR n 
1 366 PHE n 
1 367 TYR n 
1 368 TYR n 
1 369 LYS n 
1 370 SER n 
1 371 ARG n 
1 372 PHE n 
1 373 TRP n 
1 374 LEU n 
1 375 LEU n 
1 376 LYS n 
1 377 LEU n 
1 378 LEU n 
1 379 PHE n 
1 380 ARG n 
1 381 VAL n 
1 382 PHE n 
1 383 THR n 
1 384 ALA n 
1 385 PRO n 
1 386 PHE n 
1 387 HIS n 
1 388 LYS n 
1 389 VAL n 
1 390 GLY n 
1 391 PHE n 
1 392 ALA n 
1 393 ASP n 
1 394 PHE n 
1 395 TRP n 
1 396 LEU n 
1 397 ALA n 
1 398 ASP n 
1 399 GLN n 
1 400 LEU n 
1 401 ASN n 
1 402 SER n 
1 403 LEU n 
1 404 SER n 
1 405 VAL n 
1 406 ILE n 
1 407 LEU n 
1 408 MET n 
1 409 ASP n 
1 410 LEU n 
1 411 GLU n 
1 412 TYR n 
1 413 MET n 
1 414 ILE n 
1 415 CYS n 
1 416 PHE n 
1 417 TYR n 
1 418 SER n 
1 419 LEU n 
1 420 GLU n 
1 421 LEU n 
1 422 LYS n 
1 423 TRP n 
1 424 ASP n 
1 425 GLU n 
1 426 SER n 
1 427 LYS n 
1 428 GLY n 
1 429 LEU n 
1 430 LEU n 
1 431 PRO n 
1 432 ASN n 
1 433 ASN n 
1 434 SER n 
1 435 GLU n 
1 436 GLU n 
1 437 SER n 
1 438 GLY n 
1 439 ILE n 
1 440 CYS n 
1 441 HIS n 
1 442 LYS n 
1 443 TYR n 
1 444 THR n 
1 445 TYR n 
1 446 GLY n 
1 447 VAL n 
1 448 ARG n 
1 449 ALA n 
1 450 ILE n 
1 451 VAL n 
1 452 GLN n 
1 453 CYS n 
1 454 ILE n 
1 455 PRO n 
1 456 ALA n 
1 457 TRP n 
1 458 LEU n 
1 459 ARG n 
1 460 PHE n 
1 461 ILE n 
1 462 GLN n 
1 463 CYS n 
1 464 LEU n 
1 465 ARG n 
1 466 ARG n 
1 467 TYR n 
1 468 ARG n 
1 469 ASP n 
1 470 THR n 
1 471 LYS n 
1 472 ARG n 
1 473 ALA n 
1 474 PHE n 
1 475 PRO n 
1 476 HIS n 
1 477 LEU n 
1 478 VAL n 
1 479 ASN n 
1 480 ALA n 
1 481 GLY n 
1 482 LYS n 
1 483 TYR n 
1 484 SER n 
1 485 THR n 
1 486 THR n 
1 487 PHE n 
1 488 PHE n 
1 489 MET n 
1 490 VAL n 
1 491 THR n 
1 492 PHE n 
1 493 ALA n 
1 494 ALA n 
1 495 LEU n 
1 496 TYR n 
1 497 SER n 
1 498 THR n 
1 499 HIS n 
1 500 LYS n 
1 501 GLU n 
1 502 ARG n 
1 503 GLY n 
1 504 HIS n 
1 505 SER n 
1 506 ASP n 
1 507 THR n 
1 508 MET n 
1 509 VAL n 
1 510 PHE n 
1 511 PHE n 
1 512 TYR n 
1 513 LEU n 
1 514 TRP n 
1 515 ILE n 
1 516 VAL n 
1 517 PHE n 
1 518 TYR n 
1 519 ILE n 
1 520 ILE n 
1 521 SER n 
1 522 SER n 
1 523 CYS n 
1 524 TYR n 
1 525 THR n 
1 526 LEU n 
1 527 ILE n 
1 528 TRP n 
1 529 ASP n 
1 530 LEU n 
1 531 LYS n 
1 532 MET n 
1 533 ASP n 
1 534 TRP n 
1 535 GLY n 
1 536 LEU n 
1 537 PHE n 
1 538 ASP n 
1 539 LYS n 
1 540 ASN n 
1 541 ALA n 
1 542 GLY n 
1 543 GLU n 
1 544 ASN n 
1 545 THR n 
1 546 PHE n 
1 547 LEU n 
1 548 ARG n 
1 549 GLU n 
1 550 GLU n 
1 551 ILE n 
1 552 VAL n 
1 553 TYR n 
1 554 PRO n 
1 555 GLN n 
1 556 LYS n 
1 557 ALA n 
1 558 TYR n 
1 559 TYR n 
1 560 TYR n 
1 561 CYS n 
1 562 ALA n 
1 563 ILE n 
1 564 ILE n 
1 565 GLU n 
1 566 ASP n 
1 567 VAL n 
1 568 ILE n 
1 569 LEU n 
1 570 ARG n 
1 571 PHE n 
1 572 ALA n 
1 573 TRP n 
1 574 THR n 
1 575 ILE n 
1 576 GLN n 
1 577 ILE n 
1 578 SER n 
1 579 ILE n 
1 580 THR n 
1 581 SER n 
1 582 THR n 
1 583 THR n 
1 584 LEU n 
1 585 LEU n 
1 586 PRO n 
1 587 HIS n 
1 588 SER n 
1 589 GLY n 
1 590 ASP n 
1 591 ILE n 
1 592 ILE n 
1 593 ALA n 
1 594 THR n 
1 595 VAL n 
1 596 PHE n 
1 597 ALA n 
1 598 PRO n 
1 599 LEU n 
1 600 GLU n 
1 601 VAL n 
1 602 PHE n 
1 603 ARG n 
1 604 ARG n 
1 605 PHE n 
1 606 VAL n 
1 607 TRP n 
1 608 ASN n 
1 609 PHE n 
1 610 PHE n 
1 611 ARG n 
1 612 LEU n 
1 613 GLU n 
1 614 ASN n 
1 615 GLU n 
1 616 HIS n 
1 617 LEU n 
1 618 ASN n 
1 619 ASN n 
1 620 CYS n 
1 621 GLY n 
1 622 GLU n 
1 623 PHE n 
1 624 ARG n 
1 625 ALA n 
1 626 VAL n 
1 627 ARG n 
1 628 ASP n 
1 629 ILE n 
1 630 SER n 
1 631 VAL n 
1 632 ALA n 
1 633 PRO n 
1 634 LEU n 
1 635 ASN n 
1 636 ALA n 
1 637 ASP n 
1 638 ASP n 
1 639 GLN n 
1 640 THR n 
1 641 LEU n 
1 642 LEU n 
1 643 GLU n 
1 644 GLN n 
1 645 MET n 
1 646 MET n 
1 647 ASP n 
1 648 GLN n 
1 649 ASP n 
1 650 ASP n 
1 651 GLY n 
1 652 VAL n 
1 653 ARG n 
1 654 ASN n 
1 655 ARG n 
1 656 GLN n 
1 657 LYS n 
1 658 ASN n 
1 659 ARG n 
1 660 SER n 
1 661 TRP n 
1 662 LYS n 
1 663 TYR n 
1 664 ASN n 
1 665 GLN n 
1 666 SER n 
1 667 ILE n 
1 668 SER n 
1 669 LEU n 
1 670 ARG n 
1 671 ARG n 
1 672 PRO n 
1 673 ARG n 
1 674 LEU n 
1 675 ALA n 
1 676 SER n 
1 677 GLN n 
1 678 SER n 
1 679 LYS n 
1 680 ALA n 
1 681 ARG n 
1 682 ASP n 
1 683 THR n 
1 684 LYS n 
1 685 VAL n 
1 686 LEU n 
1 687 ILE n 
1 688 GLU n 
1 689 ASP n 
1 690 THR n 
1 691 ASP n 
1 692 ASP n 
1 693 GLU n 
1 694 ALA n 
1 695 ASN n 
1 696 THR n 
1 697 GLU n 
1 698 ASN n 
1 699 LEU n 
1 700 TYR n 
1 701 PHE n 
1 702 GLN n 
1 703 GLY n 
1 704 HIS n 
1 705 HIS n 
1 706 HIS n 
1 707 HIS n 
1 708 HIS n 
1 709 HIS n 
1 710 HIS n 
1 711 HIS n 
1 712 SER n 
1 713 GLY n 
1 714 ALA n 
1 715 ALA n 
1 716 ALA n 
1 717 TRP n 
1 718 SER n 
1 719 HIS n 
1 720 PRO n 
1 721 GLN n 
1 722 PHE n 
1 723 GLU n 
1 724 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   724 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'XPR1, SLC53A1, SYG1, X3' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               human 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   LYS 2   2   ?   ?   ?   A . n 
A 1 3   PHE 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   GLU 5   5   ?   ?   ?   A . n 
A 1 6   HIS 6   6   ?   ?   ?   A . n 
A 1 7   LEU 7   7   ?   ?   ?   A . n 
A 1 8   SER 8   8   ?   ?   ?   A . n 
A 1 9   ALA 9   9   ?   ?   ?   A . n 
A 1 10  HIS 10  10  ?   ?   ?   A . n 
A 1 11  ILE 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  ?   ?   ?   A . n 
A 1 13  PRO 13  13  ?   ?   ?   A . n 
A 1 14  GLU 14  14  ?   ?   ?   A . n 
A 1 15  TRP 15  15  ?   ?   ?   A . n 
A 1 16  ARG 16  16  ?   ?   ?   A . n 
A 1 17  LYS 17  17  ?   ?   ?   A . n 
A 1 18  GLN 18  18  ?   ?   ?   A . n 
A 1 19  TYR 19  19  ?   ?   ?   A . n 
A 1 20  ILE 20  20  ?   ?   ?   A . n 
A 1 21  GLN 21  21  ?   ?   ?   A . n 
A 1 22  TYR 22  22  ?   ?   ?   A . n 
A 1 23  GLU 23  23  ?   ?   ?   A . n 
A 1 24  ALA 24  24  ?   ?   ?   A . n 
A 1 25  PHE 25  25  ?   ?   ?   A . n 
A 1 26  LYS 26  26  ?   ?   ?   A . n 
A 1 27  ASP 27  27  ?   ?   ?   A . n 
A 1 28  MET 28  28  ?   ?   ?   A . n 
A 1 29  LEU 29  29  ?   ?   ?   A . n 
A 1 30  TYR 30  30  ?   ?   ?   A . n 
A 1 31  SER 31  31  ?   ?   ?   A . n 
A 1 32  ALA 32  32  ?   ?   ?   A . n 
A 1 33  GLN 33  33  ?   ?   ?   A . n 
A 1 34  ASP 34  34  ?   ?   ?   A . n 
A 1 35  GLN 35  35  ?   ?   ?   A . n 
A 1 36  ALA 36  36  ?   ?   ?   A . n 
A 1 37  PRO 37  37  ?   ?   ?   A . n 
A 1 38  SER 38  38  ?   ?   ?   A . n 
A 1 39  VAL 39  39  ?   ?   ?   A . n 
A 1 40  GLU 40  40  ?   ?   ?   A . n 
A 1 41  VAL 41  41  ?   ?   ?   A . n 
A 1 42  THR 42  42  ?   ?   ?   A . n 
A 1 43  ASP 43  43  ?   ?   ?   A . n 
A 1 44  GLU 44  44  ?   ?   ?   A . n 
A 1 45  ASP 45  45  ?   ?   ?   A . n 
A 1 46  THR 46  46  ?   ?   ?   A . n 
A 1 47  VAL 47  47  ?   ?   ?   A . n 
A 1 48  LYS 48  48  ?   ?   ?   A . n 
A 1 49  ARG 49  49  ?   ?   ?   A . n 
A 1 50  TYR 50  50  ?   ?   ?   A . n 
A 1 51  PHE 51  51  ?   ?   ?   A . n 
A 1 52  ALA 52  52  ?   ?   ?   A . n 
A 1 53  LYS 53  53  ?   ?   ?   A . n 
A 1 54  PHE 54  54  ?   ?   ?   A . n 
A 1 55  GLU 55  55  ?   ?   ?   A . n 
A 1 56  GLU 56  56  ?   ?   ?   A . n 
A 1 57  LYS 57  57  ?   ?   ?   A . n 
A 1 58  PHE 58  58  ?   ?   ?   A . n 
A 1 59  PHE 59  59  ?   ?   ?   A . n 
A 1 60  GLN 60  60  ?   ?   ?   A . n 
A 1 61  THR 61  61  ?   ?   ?   A . n 
A 1 62  CYS 62  62  ?   ?   ?   A . n 
A 1 63  GLU 63  63  ?   ?   ?   A . n 
A 1 64  LYS 64  64  ?   ?   ?   A . n 
A 1 65  GLU 65  65  ?   ?   ?   A . n 
A 1 66  LEU 66  66  ?   ?   ?   A . n 
A 1 67  ALA 67  67  ?   ?   ?   A . n 
A 1 68  LYS 68  68  ?   ?   ?   A . n 
A 1 69  ILE 69  69  ?   ?   ?   A . n 
A 1 70  ASN 70  70  ?   ?   ?   A . n 
A 1 71  THR 71  71  ?   ?   ?   A . n 
A 1 72  PHE 72  72  ?   ?   ?   A . n 
A 1 73  TYR 73  73  ?   ?   ?   A . n 
A 1 74  SER 74  74  ?   ?   ?   A . n 
A 1 75  GLU 75  75  ?   ?   ?   A . n 
A 1 76  LYS 76  76  ?   ?   ?   A . n 
A 1 77  LEU 77  77  ?   ?   ?   A . n 
A 1 78  ALA 78  78  ?   ?   ?   A . n 
A 1 79  GLU 79  79  ?   ?   ?   A . n 
A 1 80  ALA 80  80  ?   ?   ?   A . n 
A 1 81  GLN 81  81  ?   ?   ?   A . n 
A 1 82  ARG 82  82  ?   ?   ?   A . n 
A 1 83  ARG 83  83  ?   ?   ?   A . n 
A 1 84  PHE 84  84  ?   ?   ?   A . n 
A 1 85  ALA 85  85  ?   ?   ?   A . n 
A 1 86  THR 86  86  ?   ?   ?   A . n 
A 1 87  LEU 87  87  ?   ?   ?   A . n 
A 1 88  GLN 88  88  ?   ?   ?   A . n 
A 1 89  ASN 89  89  ?   ?   ?   A . n 
A 1 90  GLU 90  90  ?   ?   ?   A . n 
A 1 91  LEU 91  91  ?   ?   ?   A . n 
A 1 92  GLN 92  92  ?   ?   ?   A . n 
A 1 93  SER 93  93  ?   ?   ?   A . n 
A 1 94  SER 94  94  ?   ?   ?   A . n 
A 1 95  LEU 95  95  ?   ?   ?   A . n 
A 1 96  ASP 96  96  ?   ?   ?   A . n 
A 1 97  ALA 97  97  ?   ?   ?   A . n 
A 1 98  GLN 98  98  ?   ?   ?   A . n 
A 1 99  LYS 99  99  ?   ?   ?   A . n 
A 1 100 GLU 100 100 ?   ?   ?   A . n 
A 1 101 SER 101 101 ?   ?   ?   A . n 
A 1 102 THR 102 102 ?   ?   ?   A . n 
A 1 103 GLY 103 103 ?   ?   ?   A . n 
A 1 104 VAL 104 104 ?   ?   ?   A . n 
A 1 105 THR 105 105 ?   ?   ?   A . n 
A 1 106 THR 106 106 ?   ?   ?   A . n 
A 1 107 LEU 107 107 ?   ?   ?   A . n 
A 1 108 ARG 108 108 ?   ?   ?   A . n 
A 1 109 GLN 109 109 ?   ?   ?   A . n 
A 1 110 ARG 110 110 ?   ?   ?   A . n 
A 1 111 ARG 111 111 ?   ?   ?   A . n 
A 1 112 LYS 112 112 ?   ?   ?   A . n 
A 1 113 PRO 113 113 ?   ?   ?   A . n 
A 1 114 VAL 114 114 ?   ?   ?   A . n 
A 1 115 PHE 115 115 ?   ?   ?   A . n 
A 1 116 HIS 116 116 ?   ?   ?   A . n 
A 1 117 LEU 117 117 ?   ?   ?   A . n 
A 1 118 SER 118 118 ?   ?   ?   A . n 
A 1 119 HIS 119 119 ?   ?   ?   A . n 
A 1 120 GLU 120 120 ?   ?   ?   A . n 
A 1 121 GLU 121 121 ?   ?   ?   A . n 
A 1 122 ARG 122 122 ?   ?   ?   A . n 
A 1 123 VAL 123 123 ?   ?   ?   A . n 
A 1 124 GLN 124 124 ?   ?   ?   A . n 
A 1 125 HIS 125 125 ?   ?   ?   A . n 
A 1 126 ARG 126 126 ?   ?   ?   A . n 
A 1 127 ASN 127 127 ?   ?   ?   A . n 
A 1 128 ILE 128 128 ?   ?   ?   A . n 
A 1 129 LYS 129 129 ?   ?   ?   A . n 
A 1 130 ASP 130 130 ?   ?   ?   A . n 
A 1 131 LEU 131 131 ?   ?   ?   A . n 
A 1 132 LYS 132 132 ?   ?   ?   A . n 
A 1 133 LEU 133 133 ?   ?   ?   A . n 
A 1 134 ALA 134 134 ?   ?   ?   A . n 
A 1 135 PHE 135 135 ?   ?   ?   A . n 
A 1 136 SER 136 136 ?   ?   ?   A . n 
A 1 137 GLU 137 137 ?   ?   ?   A . n 
A 1 138 PHE 138 138 ?   ?   ?   A . n 
A 1 139 TYR 139 139 ?   ?   ?   A . n 
A 1 140 LEU 140 140 ?   ?   ?   A . n 
A 1 141 SER 141 141 ?   ?   ?   A . n 
A 1 142 LEU 142 142 ?   ?   ?   A . n 
A 1 143 ILE 143 143 ?   ?   ?   A . n 
A 1 144 LEU 144 144 ?   ?   ?   A . n 
A 1 145 LEU 145 145 ?   ?   ?   A . n 
A 1 146 GLN 146 146 ?   ?   ?   A . n 
A 1 147 ASN 147 147 ?   ?   ?   A . n 
A 1 148 TYR 148 148 ?   ?   ?   A . n 
A 1 149 GLN 149 149 ?   ?   ?   A . n 
A 1 150 ASN 150 150 ?   ?   ?   A . n 
A 1 151 LEU 151 151 ?   ?   ?   A . n 
A 1 152 ASN 152 152 ?   ?   ?   A . n 
A 1 153 PHE 153 153 ?   ?   ?   A . n 
A 1 154 THR 154 154 ?   ?   ?   A . n 
A 1 155 GLY 155 155 ?   ?   ?   A . n 
A 1 156 PHE 156 156 ?   ?   ?   A . n 
A 1 157 ARG 157 157 ?   ?   ?   A . n 
A 1 158 LYS 158 158 ?   ?   ?   A . n 
A 1 159 ILE 159 159 ?   ?   ?   A . n 
A 1 160 LEU 160 160 ?   ?   ?   A . n 
A 1 161 LYS 161 161 ?   ?   ?   A . n 
A 1 162 LYS 162 162 ?   ?   ?   A . n 
A 1 163 HIS 163 163 ?   ?   ?   A . n 
A 1 164 ASP 164 164 ?   ?   ?   A . n 
A 1 165 LYS 165 165 ?   ?   ?   A . n 
A 1 166 ILE 166 166 ?   ?   ?   A . n 
A 1 167 LEU 167 167 ?   ?   ?   A . n 
A 1 168 GLU 168 168 ?   ?   ?   A . n 
A 1 169 THR 169 169 ?   ?   ?   A . n 
A 1 170 SER 170 170 ?   ?   ?   A . n 
A 1 171 ARG 171 171 ?   ?   ?   A . n 
A 1 172 GLY 172 172 ?   ?   ?   A . n 
A 1 173 ALA 173 173 ?   ?   ?   A . n 
A 1 174 ASP 174 174 ?   ?   ?   A . n 
A 1 175 TRP 175 175 ?   ?   ?   A . n 
A 1 176 ARG 176 176 ?   ?   ?   A . n 
A 1 177 VAL 177 177 ?   ?   ?   A . n 
A 1 178 ALA 178 178 ?   ?   ?   A . n 
A 1 179 HIS 179 179 ?   ?   ?   A . n 
A 1 180 VAL 180 180 ?   ?   ?   A . n 
A 1 181 GLU 181 181 ?   ?   ?   A . n 
A 1 182 VAL 182 182 ?   ?   ?   A . n 
A 1 183 ALA 183 183 ?   ?   ?   A . n 
A 1 184 PRO 184 184 ?   ?   ?   A . n 
A 1 185 PHE 185 185 ?   ?   ?   A . n 
A 1 186 TYR 186 186 ?   ?   ?   A . n 
A 1 187 THR 187 187 ?   ?   ?   A . n 
A 1 188 CYS 188 188 ?   ?   ?   A . n 
A 1 189 LYS 189 189 ?   ?   ?   A . n 
A 1 190 LYS 190 190 ?   ?   ?   A . n 
A 1 191 ILE 191 191 ?   ?   ?   A . n 
A 1 192 ASN 192 192 ?   ?   ?   A . n 
A 1 193 GLN 193 193 ?   ?   ?   A . n 
A 1 194 LEU 194 194 ?   ?   ?   A . n 
A 1 195 ILE 195 195 ?   ?   ?   A . n 
A 1 196 SER 196 196 ?   ?   ?   A . n 
A 1 197 GLU 197 197 ?   ?   ?   A . n 
A 1 198 THR 198 198 ?   ?   ?   A . n 
A 1 199 GLU 199 199 ?   ?   ?   A . n 
A 1 200 ALA 200 200 ?   ?   ?   A . n 
A 1 201 VAL 201 201 ?   ?   ?   A . n 
A 1 202 VAL 202 202 ?   ?   ?   A . n 
A 1 203 THR 203 203 ?   ?   ?   A . n 
A 1 204 ASN 204 204 ?   ?   ?   A . n 
A 1 205 GLU 205 205 ?   ?   ?   A . n 
A 1 206 LEU 206 206 ?   ?   ?   A . n 
A 1 207 GLU 207 207 ?   ?   ?   A . n 
A 1 208 ASP 208 208 ?   ?   ?   A . n 
A 1 209 GLY 209 209 ?   ?   ?   A . n 
A 1 210 ASP 210 210 ?   ?   ?   A . n 
A 1 211 ARG 211 211 ?   ?   ?   A . n 
A 1 212 GLN 212 212 ?   ?   ?   A . n 
A 1 213 LYS 213 213 ?   ?   ?   A . n 
A 1 214 ALA 214 214 ?   ?   ?   A . n 
A 1 215 MET 215 215 ?   ?   ?   A . n 
A 1 216 LYS 216 216 ?   ?   ?   A . n 
A 1 217 ARG 217 217 ?   ?   ?   A . n 
A 1 218 LEU 218 218 ?   ?   ?   A . n 
A 1 219 ARG 219 219 ?   ?   ?   A . n 
A 1 220 VAL 220 220 ?   ?   ?   A . n 
A 1 221 PRO 221 221 ?   ?   ?   A . n 
A 1 222 PRO 222 222 ?   ?   ?   A . n 
A 1 223 LEU 223 223 ?   ?   ?   A . n 
A 1 224 GLY 224 224 ?   ?   ?   A . n 
A 1 225 ALA 225 225 ?   ?   ?   A . n 
A 1 226 ALA 226 226 ?   ?   ?   A . n 
A 1 227 GLN 227 227 ?   ?   ?   A . n 
A 1 228 PRO 228 228 ?   ?   ?   A . n 
A 1 229 ALA 229 229 ?   ?   ?   A . n 
A 1 230 PRO 230 230 ?   ?   ?   A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 TRP 232 232 232 TRP TRP A . n 
A 1 233 THR 233 233 233 THR THR A . n 
A 1 234 THR 234 234 234 THR THR A . n 
A 1 235 PHE 235 235 235 PHE PHE A . n 
A 1 236 ARG 236 236 236 ARG ARG A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 CYS 241 241 241 CYS CYS A . n 
A 1 242 GLY 242 242 242 GLY GLY A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 THR 250 250 250 THR THR A . n 
A 1 251 LEU 251 251 251 LEU LEU A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 LYS 258 258 258 LYS LYS A . n 
A 1 259 LEU 259 259 259 LEU LEU A . n 
A 1 260 GLU 260 260 260 GLU GLU A . n 
A 1 261 THR 261 261 261 THR THR A . n 
A 1 262 ASP 262 262 262 ASP ASP A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 ILE 265 265 265 ILE ILE A . n 
A 1 266 TRP 266 266 266 TRP TRP A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 ARG 270 270 270 ARG ARG A . n 
A 1 271 ILE 271 271 271 ILE ILE A . n 
A 1 272 TYR 272 272 272 TYR TYR A . n 
A 1 273 ARG 273 273 273 ARG ARG A . n 
A 1 274 GLY 274 274 274 GLY GLY A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 PHE 276 276 276 PHE PHE A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 PHE 283 283 283 PHE PHE A . n 
A 1 284 LEU 284 284 284 LEU LEU A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 GLY 286 286 286 GLY GLY A . n 
A 1 287 ILE 287 287 287 ILE ILE A . n 
A 1 288 ASN 288 288 288 ASN ASN A . n 
A 1 289 THR 289 289 289 THR THR A . n 
A 1 290 TYR 290 290 290 TYR TYR A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 TRP 292 292 292 TRP TRP A . n 
A 1 293 ARG 293 293 293 ARG ARG A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 ASN 298 298 298 ASN ASN A . n 
A 1 299 HIS 299 299 299 HIS HIS A . n 
A 1 300 VAL 300 300 300 VAL VAL A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 ILE 302 302 302 ILE ILE A . n 
A 1 303 PHE 303 303 303 PHE PHE A . n 
A 1 304 GLU 304 304 304 GLU GLU A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 ASN 306 306 306 ASN ASN A . n 
A 1 307 PRO 307 307 307 PRO PRO A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 SER 309 309 309 SER SER A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 LEU 311 311 311 LEU LEU A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 HIS 313 313 313 HIS HIS A . n 
A 1 314 GLN 314 314 314 GLN GLN A . n 
A 1 315 HIS 315 315 315 HIS HIS A . n 
A 1 316 LEU 316 316 316 LEU LEU A . n 
A 1 317 PHE 317 317 317 PHE PHE A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 PHE 322 322 322 PHE PHE A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 GLY 324 324 324 GLY GLY A . n 
A 1 325 ILE 325 325 325 ILE ILE A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 TRP 327 327 327 TRP TRP A . n 
A 1 328 CYS 328 328 328 CYS CYS A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 SER 330 330 330 SER SER A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 CYS 334 334 334 CYS CYS A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 PRO 338 338 338 PRO PRO A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 SER 340 340 340 SER SER A . n 
A 1 341 VAL 341 341 341 VAL VAL A . n 
A 1 342 ILE 342 342 342 ILE ILE A . n 
A 1 343 PRO 343 343 343 PRO PRO A . n 
A 1 344 THR 344 344 344 THR THR A . n 
A 1 345 TYR 345 345 345 TYR TYR A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 TYR 347 347 347 TYR TYR A . n 
A 1 348 PRO 348 348 348 PRO PRO A . n 
A 1 349 LEU 349 349 349 LEU LEU A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 TYR 352 352 352 TYR TYR A . n 
A 1 353 GLY 353 353 353 GLY GLY A . n 
A 1 354 PHE 354 354 354 PHE PHE A . n 
A 1 355 MET 355 355 355 MET MET A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 PHE 357 357 357 PHE PHE A . n 
A 1 358 PHE 358 358 358 PHE PHE A . n 
A 1 359 LEU 359 359 359 LEU LEU A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 ASN 361 361 361 ASN ASN A . n 
A 1 362 PRO 362 362 362 PRO PRO A . n 
A 1 363 THR 363 363 363 THR THR A . n 
A 1 364 LYS 364 364 364 LYS LYS A . n 
A 1 365 THR 365 365 365 THR THR A . n 
A 1 366 PHE 366 366 366 PHE PHE A . n 
A 1 367 TYR 367 367 367 TYR TYR A . n 
A 1 368 TYR 368 368 368 TYR TYR A . n 
A 1 369 LYS 369 369 369 LYS LYS A . n 
A 1 370 SER 370 370 370 SER SER A . n 
A 1 371 ARG 371 371 371 ARG ARG A . n 
A 1 372 PHE 372 372 372 PHE PHE A . n 
A 1 373 TRP 373 373 373 TRP TRP A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 LYS 376 376 376 LYS LYS A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 ARG 380 380 380 ARG ARG A . n 
A 1 381 VAL 381 381 381 VAL VAL A . n 
A 1 382 PHE 382 382 382 PHE PHE A . n 
A 1 383 THR 383 383 383 THR THR A . n 
A 1 384 ALA 384 384 384 ALA ALA A . n 
A 1 385 PRO 385 385 385 PRO PRO A . n 
A 1 386 PHE 386 386 386 PHE PHE A . n 
A 1 387 HIS 387 387 387 HIS HIS A . n 
A 1 388 LYS 388 388 388 LYS LYS A . n 
A 1 389 VAL 389 389 389 VAL VAL A . n 
A 1 390 GLY 390 390 390 GLY GLY A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 ASP 393 393 393 ASP ASP A . n 
A 1 394 PHE 394 394 394 PHE PHE A . n 
A 1 395 TRP 395 395 395 TRP TRP A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 ALA 397 397 397 ALA ALA A . n 
A 1 398 ASP 398 398 398 ASP ASP A . n 
A 1 399 GLN 399 399 399 GLN GLN A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 ASN 401 401 401 ASN ASN A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 SER 404 404 404 SER SER A . n 
A 1 405 VAL 405 405 405 VAL VAL A . n 
A 1 406 ILE 406 406 406 ILE ILE A . n 
A 1 407 LEU 407 407 407 LEU LEU A . n 
A 1 408 MET 408 408 408 MET MET A . n 
A 1 409 ASP 409 409 409 ASP ASP A . n 
A 1 410 LEU 410 410 410 LEU LEU A . n 
A 1 411 GLU 411 411 411 GLU GLU A . n 
A 1 412 TYR 412 412 412 TYR TYR A . n 
A 1 413 MET 413 413 413 MET MET A . n 
A 1 414 ILE 414 414 414 ILE ILE A . n 
A 1 415 CYS 415 415 415 CYS CYS A . n 
A 1 416 PHE 416 416 416 PHE PHE A . n 
A 1 417 TYR 417 417 417 TYR TYR A . n 
A 1 418 SER 418 418 418 SER SER A . n 
A 1 419 LEU 419 419 419 LEU LEU A . n 
A 1 420 GLU 420 420 420 GLU GLU A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 LYS 422 422 422 LYS ALA A . n 
A 1 423 TRP 423 423 ?   ?   ?   A . n 
A 1 424 ASP 424 424 ?   ?   ?   A . n 
A 1 425 GLU 425 425 ?   ?   ?   A . n 
A 1 426 SER 426 426 ?   ?   ?   A . n 
A 1 427 LYS 427 427 ?   ?   ?   A . n 
A 1 428 GLY 428 428 ?   ?   ?   A . n 
A 1 429 LEU 429 429 ?   ?   ?   A . n 
A 1 430 LEU 430 430 ?   ?   ?   A . n 
A 1 431 PRO 431 431 ?   ?   ?   A . n 
A 1 432 ASN 432 432 ?   ?   ?   A . n 
A 1 433 ASN 433 433 ?   ?   ?   A . n 
A 1 434 SER 434 434 ?   ?   ?   A . n 
A 1 435 GLU 435 435 ?   ?   ?   A . n 
A 1 436 GLU 436 436 ?   ?   ?   A . n 
A 1 437 SER 437 437 ?   ?   ?   A . n 
A 1 438 GLY 438 438 ?   ?   ?   A . n 
A 1 439 ILE 439 439 ?   ?   ?   A . n 
A 1 440 CYS 440 440 ?   ?   ?   A . n 
A 1 441 HIS 441 441 ?   ?   ?   A . n 
A 1 442 LYS 442 442 ?   ?   ?   A . n 
A 1 443 TYR 443 443 443 TYR TYR A . n 
A 1 444 THR 444 444 444 THR THR A . n 
A 1 445 TYR 445 445 445 TYR TYR A . n 
A 1 446 GLY 446 446 446 GLY GLY A . n 
A 1 447 VAL 447 447 447 VAL VAL A . n 
A 1 448 ARG 448 448 448 ARG ARG A . n 
A 1 449 ALA 449 449 449 ALA ALA A . n 
A 1 450 ILE 450 450 450 ILE ILE A . n 
A 1 451 VAL 451 451 451 VAL VAL A . n 
A 1 452 GLN 452 452 452 GLN GLN A . n 
A 1 453 CYS 453 453 453 CYS CYS A . n 
A 1 454 ILE 454 454 454 ILE ILE A . n 
A 1 455 PRO 455 455 455 PRO PRO A . n 
A 1 456 ALA 456 456 456 ALA ALA A . n 
A 1 457 TRP 457 457 457 TRP TRP A . n 
A 1 458 LEU 458 458 458 LEU LEU A . n 
A 1 459 ARG 459 459 459 ARG ARG A . n 
A 1 460 PHE 460 460 460 PHE PHE A . n 
A 1 461 ILE 461 461 461 ILE ILE A . n 
A 1 462 GLN 462 462 462 GLN GLN A . n 
A 1 463 CYS 463 463 463 CYS CYS A . n 
A 1 464 LEU 464 464 464 LEU LEU A . n 
A 1 465 ARG 465 465 465 ARG ARG A . n 
A 1 466 ARG 466 466 466 ARG ARG A . n 
A 1 467 TYR 467 467 467 TYR TYR A . n 
A 1 468 ARG 468 468 468 ARG ARG A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 THR 470 470 470 THR THR A . n 
A 1 471 LYS 471 471 471 LYS LYS A . n 
A 1 472 ARG 472 472 472 ARG ARG A . n 
A 1 473 ALA 473 473 473 ALA ALA A . n 
A 1 474 PHE 474 474 474 PHE PHE A . n 
A 1 475 PRO 475 475 475 PRO PRO A . n 
A 1 476 HIS 476 476 476 HIS HIS A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 VAL 478 478 478 VAL VAL A . n 
A 1 479 ASN 479 479 479 ASN ASN A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 GLY 481 481 481 GLY GLY A . n 
A 1 482 LYS 482 482 482 LYS LYS A . n 
A 1 483 TYR 483 483 483 TYR TYR A . n 
A 1 484 SER 484 484 484 SER SER A . n 
A 1 485 THR 485 485 485 THR THR A . n 
A 1 486 THR 486 486 486 THR THR A . n 
A 1 487 PHE 487 487 487 PHE PHE A . n 
A 1 488 PHE 488 488 488 PHE PHE A . n 
A 1 489 MET 489 489 489 MET MET A . n 
A 1 490 VAL 490 490 490 VAL VAL A . n 
A 1 491 THR 491 491 491 THR THR A . n 
A 1 492 PHE 492 492 492 PHE PHE A . n 
A 1 493 ALA 493 493 493 ALA ALA A . n 
A 1 494 ALA 494 494 494 ALA ALA A . n 
A 1 495 LEU 495 495 495 LEU LEU A . n 
A 1 496 TYR 496 496 496 TYR TYR A . n 
A 1 497 SER 497 497 497 SER SER A . n 
A 1 498 THR 498 498 498 THR THR A . n 
A 1 499 HIS 499 499 499 HIS HIS A . n 
A 1 500 LYS 500 500 500 LYS LYS A . n 
A 1 501 GLU 501 501 501 GLU GLU A . n 
A 1 502 ARG 502 502 502 ARG ARG A . n 
A 1 503 GLY 503 503 503 GLY GLY A . n 
A 1 504 HIS 504 504 504 HIS HIS A . n 
A 1 505 SER 505 505 505 SER SER A . n 
A 1 506 ASP 506 506 506 ASP ASP A . n 
A 1 507 THR 507 507 507 THR THR A . n 
A 1 508 MET 508 508 508 MET MET A . n 
A 1 509 VAL 509 509 509 VAL VAL A . n 
A 1 510 PHE 510 510 510 PHE PHE A . n 
A 1 511 PHE 511 511 511 PHE PHE A . n 
A 1 512 TYR 512 512 512 TYR TYR A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 TRP 514 514 514 TRP TRP A . n 
A 1 515 ILE 515 515 515 ILE ILE A . n 
A 1 516 VAL 516 516 516 VAL VAL A . n 
A 1 517 PHE 517 517 517 PHE PHE A . n 
A 1 518 TYR 518 518 518 TYR TYR A . n 
A 1 519 ILE 519 519 519 ILE ILE A . n 
A 1 520 ILE 520 520 520 ILE ILE A . n 
A 1 521 SER 521 521 521 SER SER A . n 
A 1 522 SER 522 522 522 SER SER A . n 
A 1 523 CYS 523 523 523 CYS CYS A . n 
A 1 524 TYR 524 524 524 TYR TYR A . n 
A 1 525 THR 525 525 525 THR THR A . n 
A 1 526 LEU 526 526 526 LEU LEU A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 TRP 528 528 528 TRP TRP A . n 
A 1 529 ASP 529 529 529 ASP ASP A . n 
A 1 530 LEU 530 530 530 LEU LEU A . n 
A 1 531 LYS 531 531 531 LYS LYS A . n 
A 1 532 MET 532 532 532 MET MET A . n 
A 1 533 ASP 533 533 533 ASP ASP A . n 
A 1 534 TRP 534 534 534 TRP TRP A . n 
A 1 535 GLY 535 535 535 GLY GLY A . n 
A 1 536 LEU 536 536 536 LEU LEU A . n 
A 1 537 PHE 537 537 537 PHE PHE A . n 
A 1 538 ASP 538 538 538 ASP ASP A . n 
A 1 539 LYS 539 539 539 LYS LYS A . n 
A 1 540 ASN 540 540 540 ASN ASN A . n 
A 1 541 ALA 541 541 541 ALA ALA A . n 
A 1 542 GLY 542 542 542 GLY GLY A . n 
A 1 543 GLU 543 543 543 GLU GLU A . n 
A 1 544 ASN 544 544 544 ASN ASN A . n 
A 1 545 THR 545 545 545 THR THR A . n 
A 1 546 PHE 546 546 546 PHE PHE A . n 
A 1 547 LEU 547 547 547 LEU LEU A . n 
A 1 548 ARG 548 548 548 ARG ARG A . n 
A 1 549 GLU 549 549 549 GLU GLU A . n 
A 1 550 GLU 550 550 550 GLU GLU A . n 
A 1 551 ILE 551 551 551 ILE ILE A . n 
A 1 552 VAL 552 552 552 VAL VAL A . n 
A 1 553 TYR 553 553 553 TYR TYR A . n 
A 1 554 PRO 554 554 554 PRO PRO A . n 
A 1 555 GLN 555 555 555 GLN GLN A . n 
A 1 556 LYS 556 556 556 LYS LYS A . n 
A 1 557 ALA 557 557 557 ALA ALA A . n 
A 1 558 TYR 558 558 558 TYR TYR A . n 
A 1 559 TYR 559 559 559 TYR TYR A . n 
A 1 560 TYR 560 560 560 TYR TYR A . n 
A 1 561 CYS 561 561 561 CYS CYS A . n 
A 1 562 ALA 562 562 562 ALA ALA A . n 
A 1 563 ILE 563 563 563 ILE ILE A . n 
A 1 564 ILE 564 564 564 ILE ILE A . n 
A 1 565 GLU 565 565 565 GLU GLU A . n 
A 1 566 ASP 566 566 566 ASP ASP A . n 
A 1 567 VAL 567 567 567 VAL VAL A . n 
A 1 568 ILE 568 568 568 ILE ILE A . n 
A 1 569 LEU 569 569 569 LEU LEU A . n 
A 1 570 ARG 570 570 570 ARG ARG A . n 
A 1 571 PHE 571 571 571 PHE PHE A . n 
A 1 572 ALA 572 572 572 ALA ALA A . n 
A 1 573 TRP 573 573 573 TRP TRP A . n 
A 1 574 THR 574 574 574 THR THR A . n 
A 1 575 ILE 575 575 575 ILE ILE A . n 
A 1 576 GLN 576 576 576 GLN GLN A . n 
A 1 577 ILE 577 577 577 ILE ILE A . n 
A 1 578 SER 578 578 578 SER SER A . n 
A 1 579 ILE 579 579 579 ILE ILE A . n 
A 1 580 THR 580 580 580 THR THR A . n 
A 1 581 SER 581 581 581 SER SER A . n 
A 1 582 THR 582 582 582 THR THR A . n 
A 1 583 THR 583 583 583 THR THR A . n 
A 1 584 LEU 584 584 584 LEU LEU A . n 
A 1 585 LEU 585 585 585 LEU LEU A . n 
A 1 586 PRO 586 586 586 PRO PRO A . n 
A 1 587 HIS 587 587 587 HIS HIS A . n 
A 1 588 SER 588 588 588 SER SER A . n 
A 1 589 GLY 589 589 589 GLY GLY A . n 
A 1 590 ASP 590 590 590 ASP ASP A . n 
A 1 591 ILE 591 591 591 ILE ILE A . n 
A 1 592 ILE 592 592 592 ILE ILE A . n 
A 1 593 ALA 593 593 593 ALA ALA A . n 
A 1 594 THR 594 594 594 THR THR A . n 
A 1 595 VAL 595 595 595 VAL VAL A . n 
A 1 596 PHE 596 596 596 PHE PHE A . n 
A 1 597 ALA 597 597 597 ALA ALA A . n 
A 1 598 PRO 598 598 598 PRO PRO A . n 
A 1 599 LEU 599 599 599 LEU LEU A . n 
A 1 600 GLU 600 600 600 GLU GLU A . n 
A 1 601 VAL 601 601 601 VAL VAL A . n 
A 1 602 PHE 602 602 602 PHE PHE A . n 
A 1 603 ARG 603 603 603 ARG ARG A . n 
A 1 604 ARG 604 604 604 ARG ARG A . n 
A 1 605 PHE 605 605 605 PHE PHE A . n 
A 1 606 VAL 606 606 606 VAL VAL A . n 
A 1 607 TRP 607 607 607 TRP TRP A . n 
A 1 608 ASN 608 608 608 ASN ASN A . n 
A 1 609 PHE 609 609 609 PHE PHE A . n 
A 1 610 PHE 610 610 610 PHE PHE A . n 
A 1 611 ARG 611 611 611 ARG ARG A . n 
A 1 612 LEU 612 612 612 LEU LEU A . n 
A 1 613 GLU 613 613 613 GLU GLU A . n 
A 1 614 ASN 614 614 614 ASN ASN A . n 
A 1 615 GLU 615 615 615 GLU GLU A . n 
A 1 616 HIS 616 616 616 HIS HIS A . n 
A 1 617 LEU 617 617 617 LEU LEU A . n 
A 1 618 ASN 618 618 618 ASN ASN A . n 
A 1 619 ASN 619 619 619 ASN ASN A . n 
A 1 620 CYS 620 620 620 CYS CYS A . n 
A 1 621 GLY 621 621 621 GLY GLY A . n 
A 1 622 GLU 622 622 622 GLU GLU A . n 
A 1 623 PHE 623 623 623 PHE PHE A . n 
A 1 624 ARG 624 624 624 ARG ARG A . n 
A 1 625 ALA 625 625 625 ALA ALA A . n 
A 1 626 VAL 626 626 ?   ?   ?   A . n 
A 1 627 ARG 627 627 ?   ?   ?   A . n 
A 1 628 ASP 628 628 ?   ?   ?   A . n 
A 1 629 ILE 629 629 ?   ?   ?   A . n 
A 1 630 SER 630 630 ?   ?   ?   A . n 
A 1 631 VAL 631 631 ?   ?   ?   A . n 
A 1 632 ALA 632 632 ?   ?   ?   A . n 
A 1 633 PRO 633 633 ?   ?   ?   A . n 
A 1 634 LEU 634 634 ?   ?   ?   A . n 
A 1 635 ASN 635 635 ?   ?   ?   A . n 
A 1 636 ALA 636 636 ?   ?   ?   A . n 
A 1 637 ASP 637 637 ?   ?   ?   A . n 
A 1 638 ASP 638 638 ?   ?   ?   A . n 
A 1 639 GLN 639 639 ?   ?   ?   A . n 
A 1 640 THR 640 640 ?   ?   ?   A . n 
A 1 641 LEU 641 641 ?   ?   ?   A . n 
A 1 642 LEU 642 642 ?   ?   ?   A . n 
A 1 643 GLU 643 643 ?   ?   ?   A . n 
A 1 644 GLN 644 644 ?   ?   ?   A . n 
A 1 645 MET 645 645 ?   ?   ?   A . n 
A 1 646 MET 646 646 ?   ?   ?   A . n 
A 1 647 ASP 647 647 ?   ?   ?   A . n 
A 1 648 GLN 648 648 ?   ?   ?   A . n 
A 1 649 ASP 649 649 ?   ?   ?   A . n 
A 1 650 ASP 650 650 ?   ?   ?   A . n 
A 1 651 GLY 651 651 ?   ?   ?   A . n 
A 1 652 VAL 652 652 ?   ?   ?   A . n 
A 1 653 ARG 653 653 ?   ?   ?   A . n 
A 1 654 ASN 654 654 ?   ?   ?   A . n 
A 1 655 ARG 655 655 ?   ?   ?   A . n 
A 1 656 GLN 656 656 ?   ?   ?   A . n 
A 1 657 LYS 657 657 ?   ?   ?   A . n 
A 1 658 ASN 658 658 ?   ?   ?   A . n 
A 1 659 ARG 659 659 ?   ?   ?   A . n 
A 1 660 SER 660 660 ?   ?   ?   A . n 
A 1 661 TRP 661 661 ?   ?   ?   A . n 
A 1 662 LYS 662 662 ?   ?   ?   A . n 
A 1 663 TYR 663 663 ?   ?   ?   A . n 
A 1 664 ASN 664 664 ?   ?   ?   A . n 
A 1 665 GLN 665 665 ?   ?   ?   A . n 
A 1 666 SER 666 666 ?   ?   ?   A . n 
A 1 667 ILE 667 667 ?   ?   ?   A . n 
A 1 668 SER 668 668 ?   ?   ?   A . n 
A 1 669 LEU 669 669 ?   ?   ?   A . n 
A 1 670 ARG 670 670 ?   ?   ?   A . n 
A 1 671 ARG 671 671 ?   ?   ?   A . n 
A 1 672 PRO 672 672 ?   ?   ?   A . n 
A 1 673 ARG 673 673 ?   ?   ?   A . n 
A 1 674 LEU 674 674 ?   ?   ?   A . n 
A 1 675 ALA 675 675 ?   ?   ?   A . n 
A 1 676 SER 676 676 ?   ?   ?   A . n 
A 1 677 GLN 677 677 ?   ?   ?   A . n 
A 1 678 SER 678 678 ?   ?   ?   A . n 
A 1 679 LYS 679 679 ?   ?   ?   A . n 
A 1 680 ALA 680 680 ?   ?   ?   A . n 
A 1 681 ARG 681 681 ?   ?   ?   A . n 
A 1 682 ASP 682 682 ?   ?   ?   A . n 
A 1 683 THR 683 683 ?   ?   ?   A . n 
A 1 684 LYS 684 684 ?   ?   ?   A . n 
A 1 685 VAL 685 685 ?   ?   ?   A . n 
A 1 686 LEU 686 686 ?   ?   ?   A . n 
A 1 687 ILE 687 687 ?   ?   ?   A . n 
A 1 688 GLU 688 688 ?   ?   ?   A . n 
A 1 689 ASP 689 689 ?   ?   ?   A . n 
A 1 690 THR 690 690 ?   ?   ?   A . n 
A 1 691 ASP 691 691 ?   ?   ?   A . n 
A 1 692 ASP 692 692 ?   ?   ?   A . n 
A 1 693 GLU 693 693 ?   ?   ?   A . n 
A 1 694 ALA 694 694 ?   ?   ?   A . n 
A 1 695 ASN 695 695 ?   ?   ?   A . n 
A 1 696 THR 696 696 ?   ?   ?   A . n 
A 1 697 GLU 697 697 ?   ?   ?   A . n 
A 1 698 ASN 698 698 ?   ?   ?   A . n 
A 1 699 LEU 699 699 ?   ?   ?   A . n 
A 1 700 TYR 700 700 ?   ?   ?   A . n 
A 1 701 PHE 701 701 ?   ?   ?   A . n 
A 1 702 GLN 702 702 ?   ?   ?   A . n 
A 1 703 GLY 703 703 ?   ?   ?   A . n 
A 1 704 HIS 704 704 ?   ?   ?   A . n 
A 1 705 HIS 705 705 ?   ?   ?   A . n 
A 1 706 HIS 706 706 ?   ?   ?   A . n 
A 1 707 HIS 707 707 ?   ?   ?   A . n 
A 1 708 HIS 708 708 ?   ?   ?   A . n 
A 1 709 HIS 709 709 ?   ?   ?   A . n 
A 1 710 HIS 710 710 ?   ?   ?   A . n 
A 1 711 HIS 711 711 ?   ?   ?   A . n 
A 1 712 SER 712 712 ?   ?   ?   A . n 
A 1 713 GLY 713 713 ?   ?   ?   A . n 
A 1 714 ALA 714 714 ?   ?   ?   A . n 
A 1 715 ALA 715 715 ?   ?   ?   A . n 
A 1 716 ALA 716 716 ?   ?   ?   A . n 
A 1 717 TRP 717 717 ?   ?   ?   A . n 
A 1 718 SER 718 718 ?   ?   ?   A . n 
A 1 719 HIS 719 719 ?   ?   ?   A . n 
A 1 720 PRO 720 720 ?   ?   ?   A . n 
A 1 721 GLN 721 721 ?   ?   ?   A . n 
A 1 722 PHE 722 722 ?   ?   ?   A . n 
A 1 723 GLU 723 723 ?   ?   ?   A . n 
A 1 724 LYS 724 724 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   LYS 2   2   ?   ?   ?   B . n 
B 1 3   PHE 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   GLU 5   5   ?   ?   ?   B . n 
B 1 6   HIS 6   6   ?   ?   ?   B . n 
B 1 7   LEU 7   7   ?   ?   ?   B . n 
B 1 8   SER 8   8   ?   ?   ?   B . n 
B 1 9   ALA 9   9   ?   ?   ?   B . n 
B 1 10  HIS 10  10  ?   ?   ?   B . n 
B 1 11  ILE 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  ?   ?   ?   B . n 
B 1 13  PRO 13  13  ?   ?   ?   B . n 
B 1 14  GLU 14  14  ?   ?   ?   B . n 
B 1 15  TRP 15  15  ?   ?   ?   B . n 
B 1 16  ARG 16  16  ?   ?   ?   B . n 
B 1 17  LYS 17  17  ?   ?   ?   B . n 
B 1 18  GLN 18  18  ?   ?   ?   B . n 
B 1 19  TYR 19  19  ?   ?   ?   B . n 
B 1 20  ILE 20  20  ?   ?   ?   B . n 
B 1 21  GLN 21  21  ?   ?   ?   B . n 
B 1 22  TYR 22  22  ?   ?   ?   B . n 
B 1 23  GLU 23  23  ?   ?   ?   B . n 
B 1 24  ALA 24  24  ?   ?   ?   B . n 
B 1 25  PHE 25  25  ?   ?   ?   B . n 
B 1 26  LYS 26  26  ?   ?   ?   B . n 
B 1 27  ASP 27  27  ?   ?   ?   B . n 
B 1 28  MET 28  28  ?   ?   ?   B . n 
B 1 29  LEU 29  29  ?   ?   ?   B . n 
B 1 30  TYR 30  30  ?   ?   ?   B . n 
B 1 31  SER 31  31  ?   ?   ?   B . n 
B 1 32  ALA 32  32  ?   ?   ?   B . n 
B 1 33  GLN 33  33  ?   ?   ?   B . n 
B 1 34  ASP 34  34  ?   ?   ?   B . n 
B 1 35  GLN 35  35  ?   ?   ?   B . n 
B 1 36  ALA 36  36  ?   ?   ?   B . n 
B 1 37  PRO 37  37  ?   ?   ?   B . n 
B 1 38  SER 38  38  ?   ?   ?   B . n 
B 1 39  VAL 39  39  ?   ?   ?   B . n 
B 1 40  GLU 40  40  ?   ?   ?   B . n 
B 1 41  VAL 41  41  ?   ?   ?   B . n 
B 1 42  THR 42  42  ?   ?   ?   B . n 
B 1 43  ASP 43  43  ?   ?   ?   B . n 
B 1 44  GLU 44  44  ?   ?   ?   B . n 
B 1 45  ASP 45  45  ?   ?   ?   B . n 
B 1 46  THR 46  46  ?   ?   ?   B . n 
B 1 47  VAL 47  47  ?   ?   ?   B . n 
B 1 48  LYS 48  48  ?   ?   ?   B . n 
B 1 49  ARG 49  49  ?   ?   ?   B . n 
B 1 50  TYR 50  50  ?   ?   ?   B . n 
B 1 51  PHE 51  51  ?   ?   ?   B . n 
B 1 52  ALA 52  52  ?   ?   ?   B . n 
B 1 53  LYS 53  53  ?   ?   ?   B . n 
B 1 54  PHE 54  54  ?   ?   ?   B . n 
B 1 55  GLU 55  55  ?   ?   ?   B . n 
B 1 56  GLU 56  56  ?   ?   ?   B . n 
B 1 57  LYS 57  57  ?   ?   ?   B . n 
B 1 58  PHE 58  58  ?   ?   ?   B . n 
B 1 59  PHE 59  59  ?   ?   ?   B . n 
B 1 60  GLN 60  60  ?   ?   ?   B . n 
B 1 61  THR 61  61  ?   ?   ?   B . n 
B 1 62  CYS 62  62  ?   ?   ?   B . n 
B 1 63  GLU 63  63  ?   ?   ?   B . n 
B 1 64  LYS 64  64  ?   ?   ?   B . n 
B 1 65  GLU 65  65  ?   ?   ?   B . n 
B 1 66  LEU 66  66  ?   ?   ?   B . n 
B 1 67  ALA 67  67  ?   ?   ?   B . n 
B 1 68  LYS 68  68  ?   ?   ?   B . n 
B 1 69  ILE 69  69  ?   ?   ?   B . n 
B 1 70  ASN 70  70  ?   ?   ?   B . n 
B 1 71  THR 71  71  ?   ?   ?   B . n 
B 1 72  PHE 72  72  ?   ?   ?   B . n 
B 1 73  TYR 73  73  ?   ?   ?   B . n 
B 1 74  SER 74  74  ?   ?   ?   B . n 
B 1 75  GLU 75  75  ?   ?   ?   B . n 
B 1 76  LYS 76  76  ?   ?   ?   B . n 
B 1 77  LEU 77  77  ?   ?   ?   B . n 
B 1 78  ALA 78  78  ?   ?   ?   B . n 
B 1 79  GLU 79  79  ?   ?   ?   B . n 
B 1 80  ALA 80  80  ?   ?   ?   B . n 
B 1 81  GLN 81  81  ?   ?   ?   B . n 
B 1 82  ARG 82  82  ?   ?   ?   B . n 
B 1 83  ARG 83  83  ?   ?   ?   B . n 
B 1 84  PHE 84  84  ?   ?   ?   B . n 
B 1 85  ALA 85  85  ?   ?   ?   B . n 
B 1 86  THR 86  86  ?   ?   ?   B . n 
B 1 87  LEU 87  87  ?   ?   ?   B . n 
B 1 88  GLN 88  88  ?   ?   ?   B . n 
B 1 89  ASN 89  89  ?   ?   ?   B . n 
B 1 90  GLU 90  90  ?   ?   ?   B . n 
B 1 91  LEU 91  91  ?   ?   ?   B . n 
B 1 92  GLN 92  92  ?   ?   ?   B . n 
B 1 93  SER 93  93  ?   ?   ?   B . n 
B 1 94  SER 94  94  ?   ?   ?   B . n 
B 1 95  LEU 95  95  ?   ?   ?   B . n 
B 1 96  ASP 96  96  ?   ?   ?   B . n 
B 1 97  ALA 97  97  ?   ?   ?   B . n 
B 1 98  GLN 98  98  ?   ?   ?   B . n 
B 1 99  LYS 99  99  ?   ?   ?   B . n 
B 1 100 GLU 100 100 ?   ?   ?   B . n 
B 1 101 SER 101 101 ?   ?   ?   B . n 
B 1 102 THR 102 102 ?   ?   ?   B . n 
B 1 103 GLY 103 103 ?   ?   ?   B . n 
B 1 104 VAL 104 104 ?   ?   ?   B . n 
B 1 105 THR 105 105 ?   ?   ?   B . n 
B 1 106 THR 106 106 ?   ?   ?   B . n 
B 1 107 LEU 107 107 ?   ?   ?   B . n 
B 1 108 ARG 108 108 ?   ?   ?   B . n 
B 1 109 GLN 109 109 ?   ?   ?   B . n 
B 1 110 ARG 110 110 ?   ?   ?   B . n 
B 1 111 ARG 111 111 ?   ?   ?   B . n 
B 1 112 LYS 112 112 ?   ?   ?   B . n 
B 1 113 PRO 113 113 ?   ?   ?   B . n 
B 1 114 VAL 114 114 ?   ?   ?   B . n 
B 1 115 PHE 115 115 ?   ?   ?   B . n 
B 1 116 HIS 116 116 ?   ?   ?   B . n 
B 1 117 LEU 117 117 ?   ?   ?   B . n 
B 1 118 SER 118 118 ?   ?   ?   B . n 
B 1 119 HIS 119 119 ?   ?   ?   B . n 
B 1 120 GLU 120 120 ?   ?   ?   B . n 
B 1 121 GLU 121 121 ?   ?   ?   B . n 
B 1 122 ARG 122 122 ?   ?   ?   B . n 
B 1 123 VAL 123 123 ?   ?   ?   B . n 
B 1 124 GLN 124 124 ?   ?   ?   B . n 
B 1 125 HIS 125 125 ?   ?   ?   B . n 
B 1 126 ARG 126 126 ?   ?   ?   B . n 
B 1 127 ASN 127 127 ?   ?   ?   B . n 
B 1 128 ILE 128 128 ?   ?   ?   B . n 
B 1 129 LYS 129 129 ?   ?   ?   B . n 
B 1 130 ASP 130 130 ?   ?   ?   B . n 
B 1 131 LEU 131 131 ?   ?   ?   B . n 
B 1 132 LYS 132 132 ?   ?   ?   B . n 
B 1 133 LEU 133 133 ?   ?   ?   B . n 
B 1 134 ALA 134 134 ?   ?   ?   B . n 
B 1 135 PHE 135 135 ?   ?   ?   B . n 
B 1 136 SER 136 136 ?   ?   ?   B . n 
B 1 137 GLU 137 137 ?   ?   ?   B . n 
B 1 138 PHE 138 138 ?   ?   ?   B . n 
B 1 139 TYR 139 139 ?   ?   ?   B . n 
B 1 140 LEU 140 140 ?   ?   ?   B . n 
B 1 141 SER 141 141 ?   ?   ?   B . n 
B 1 142 LEU 142 142 ?   ?   ?   B . n 
B 1 143 ILE 143 143 ?   ?   ?   B . n 
B 1 144 LEU 144 144 ?   ?   ?   B . n 
B 1 145 LEU 145 145 ?   ?   ?   B . n 
B 1 146 GLN 146 146 ?   ?   ?   B . n 
B 1 147 ASN 147 147 ?   ?   ?   B . n 
B 1 148 TYR 148 148 ?   ?   ?   B . n 
B 1 149 GLN 149 149 ?   ?   ?   B . n 
B 1 150 ASN 150 150 ?   ?   ?   B . n 
B 1 151 LEU 151 151 ?   ?   ?   B . n 
B 1 152 ASN 152 152 ?   ?   ?   B . n 
B 1 153 PHE 153 153 ?   ?   ?   B . n 
B 1 154 THR 154 154 ?   ?   ?   B . n 
B 1 155 GLY 155 155 ?   ?   ?   B . n 
B 1 156 PHE 156 156 ?   ?   ?   B . n 
B 1 157 ARG 157 157 ?   ?   ?   B . n 
B 1 158 LYS 158 158 ?   ?   ?   B . n 
B 1 159 ILE 159 159 ?   ?   ?   B . n 
B 1 160 LEU 160 160 ?   ?   ?   B . n 
B 1 161 LYS 161 161 ?   ?   ?   B . n 
B 1 162 LYS 162 162 ?   ?   ?   B . n 
B 1 163 HIS 163 163 ?   ?   ?   B . n 
B 1 164 ASP 164 164 ?   ?   ?   B . n 
B 1 165 LYS 165 165 ?   ?   ?   B . n 
B 1 166 ILE 166 166 ?   ?   ?   B . n 
B 1 167 LEU 167 167 ?   ?   ?   B . n 
B 1 168 GLU 168 168 ?   ?   ?   B . n 
B 1 169 THR 169 169 ?   ?   ?   B . n 
B 1 170 SER 170 170 ?   ?   ?   B . n 
B 1 171 ARG 171 171 ?   ?   ?   B . n 
B 1 172 GLY 172 172 ?   ?   ?   B . n 
B 1 173 ALA 173 173 ?   ?   ?   B . n 
B 1 174 ASP 174 174 ?   ?   ?   B . n 
B 1 175 TRP 175 175 ?   ?   ?   B . n 
B 1 176 ARG 176 176 ?   ?   ?   B . n 
B 1 177 VAL 177 177 ?   ?   ?   B . n 
B 1 178 ALA 178 178 ?   ?   ?   B . n 
B 1 179 HIS 179 179 ?   ?   ?   B . n 
B 1 180 VAL 180 180 ?   ?   ?   B . n 
B 1 181 GLU 181 181 ?   ?   ?   B . n 
B 1 182 VAL 182 182 ?   ?   ?   B . n 
B 1 183 ALA 183 183 ?   ?   ?   B . n 
B 1 184 PRO 184 184 ?   ?   ?   B . n 
B 1 185 PHE 185 185 ?   ?   ?   B . n 
B 1 186 TYR 186 186 ?   ?   ?   B . n 
B 1 187 THR 187 187 ?   ?   ?   B . n 
B 1 188 CYS 188 188 ?   ?   ?   B . n 
B 1 189 LYS 189 189 ?   ?   ?   B . n 
B 1 190 LYS 190 190 ?   ?   ?   B . n 
B 1 191 ILE 191 191 ?   ?   ?   B . n 
B 1 192 ASN 192 192 ?   ?   ?   B . n 
B 1 193 GLN 193 193 ?   ?   ?   B . n 
B 1 194 LEU 194 194 ?   ?   ?   B . n 
B 1 195 ILE 195 195 ?   ?   ?   B . n 
B 1 196 SER 196 196 ?   ?   ?   B . n 
B 1 197 GLU 197 197 ?   ?   ?   B . n 
B 1 198 THR 198 198 ?   ?   ?   B . n 
B 1 199 GLU 199 199 ?   ?   ?   B . n 
B 1 200 ALA 200 200 ?   ?   ?   B . n 
B 1 201 VAL 201 201 ?   ?   ?   B . n 
B 1 202 VAL 202 202 ?   ?   ?   B . n 
B 1 203 THR 203 203 ?   ?   ?   B . n 
B 1 204 ASN 204 204 ?   ?   ?   B . n 
B 1 205 GLU 205 205 ?   ?   ?   B . n 
B 1 206 LEU 206 206 ?   ?   ?   B . n 
B 1 207 GLU 207 207 ?   ?   ?   B . n 
B 1 208 ASP 208 208 ?   ?   ?   B . n 
B 1 209 GLY 209 209 ?   ?   ?   B . n 
B 1 210 ASP 210 210 ?   ?   ?   B . n 
B 1 211 ARG 211 211 ?   ?   ?   B . n 
B 1 212 GLN 212 212 ?   ?   ?   B . n 
B 1 213 LYS 213 213 ?   ?   ?   B . n 
B 1 214 ALA 214 214 ?   ?   ?   B . n 
B 1 215 MET 215 215 ?   ?   ?   B . n 
B 1 216 LYS 216 216 ?   ?   ?   B . n 
B 1 217 ARG 217 217 ?   ?   ?   B . n 
B 1 218 LEU 218 218 ?   ?   ?   B . n 
B 1 219 ARG 219 219 ?   ?   ?   B . n 
B 1 220 VAL 220 220 ?   ?   ?   B . n 
B 1 221 PRO 221 221 ?   ?   ?   B . n 
B 1 222 PRO 222 222 ?   ?   ?   B . n 
B 1 223 LEU 223 223 ?   ?   ?   B . n 
B 1 224 GLY 224 224 ?   ?   ?   B . n 
B 1 225 ALA 225 225 ?   ?   ?   B . n 
B 1 226 ALA 226 226 ?   ?   ?   B . n 
B 1 227 GLN 227 227 ?   ?   ?   B . n 
B 1 228 PRO 228 228 ?   ?   ?   B . n 
B 1 229 ALA 229 229 ?   ?   ?   B . n 
B 1 230 PRO 230 230 ?   ?   ?   B . n 
B 1 231 ALA 231 231 231 ALA ALA B . n 
B 1 232 TRP 232 232 232 TRP TRP B . n 
B 1 233 THR 233 233 233 THR THR B . n 
B 1 234 THR 234 234 234 THR THR B . n 
B 1 235 PHE 235 235 235 PHE PHE B . n 
B 1 236 ARG 236 236 236 ARG ARG B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 PHE 240 240 240 PHE PHE B . n 
B 1 241 CYS 241 241 241 CYS CYS B . n 
B 1 242 GLY 242 242 242 GLY GLY B . n 
B 1 243 ILE 243 243 243 ILE ILE B . n 
B 1 244 PHE 244 244 244 PHE PHE B . n 
B 1 245 ILE 245 245 245 ILE ILE B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 LEU 247 247 247 LEU LEU B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 ILE 249 249 249 ILE ILE B . n 
B 1 250 THR 250 250 250 THR THR B . n 
B 1 251 LEU 251 251 251 LEU LEU B . n 
B 1 252 VAL 252 252 252 VAL VAL B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 VAL 256 256 256 VAL VAL B . n 
B 1 257 PHE 257 257 257 PHE PHE B . n 
B 1 258 LYS 258 258 258 LYS LYS B . n 
B 1 259 LEU 259 259 259 LEU LEU B . n 
B 1 260 GLU 260 260 260 GLU GLU B . n 
B 1 261 THR 261 261 261 THR THR B . n 
B 1 262 ASP 262 262 262 ASP ASP B . n 
B 1 263 ARG 263 263 263 ARG ARG B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 ILE 265 265 265 ILE ILE B . n 
B 1 266 TRP 266 266 266 TRP TRP B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 ARG 270 270 270 ARG ARG B . n 
B 1 271 ILE 271 271 271 ILE ILE B . n 
B 1 272 TYR 272 272 272 TYR TYR B . n 
B 1 273 ARG 273 273 273 ARG ARG B . n 
B 1 274 GLY 274 274 274 GLY GLY B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 PHE 276 276 276 PHE PHE B . n 
B 1 277 LEU 277 277 277 LEU LEU B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 PHE 281 281 281 PHE PHE B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 PHE 283 283 283 PHE PHE B . n 
B 1 284 LEU 284 284 284 LEU LEU B . n 
B 1 285 LEU 285 285 285 LEU LEU B . n 
B 1 286 GLY 286 286 286 GLY GLY B . n 
B 1 287 ILE 287 287 287 ILE ILE B . n 
B 1 288 ASN 288 288 288 ASN ASN B . n 
B 1 289 THR 289 289 289 THR THR B . n 
B 1 290 TYR 290 290 290 TYR TYR B . n 
B 1 291 GLY 291 291 291 GLY GLY B . n 
B 1 292 TRP 292 292 292 TRP TRP B . n 
B 1 293 ARG 293 293 293 ARG ARG B . n 
B 1 294 GLN 294 294 294 GLN GLN B . n 
B 1 295 ALA 295 295 295 ALA ALA B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 VAL 297 297 297 VAL VAL B . n 
B 1 298 ASN 298 298 298 ASN ASN B . n 
B 1 299 HIS 299 299 299 HIS HIS B . n 
B 1 300 VAL 300 300 300 VAL VAL B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 ILE 302 302 302 ILE ILE B . n 
B 1 303 PHE 303 303 303 PHE PHE B . n 
B 1 304 GLU 304 304 304 GLU GLU B . n 
B 1 305 LEU 305 305 305 LEU LEU B . n 
B 1 306 ASN 306 306 306 ASN ASN B . n 
B 1 307 PRO 307 307 307 PRO PRO B . n 
B 1 308 ARG 308 308 308 ARG ARG B . n 
B 1 309 SER 309 309 309 SER SER B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 LEU 311 311 311 LEU LEU B . n 
B 1 312 SER 312 312 312 SER SER B . n 
B 1 313 HIS 313 313 313 HIS HIS B . n 
B 1 314 GLN 314 314 314 GLN GLN B . n 
B 1 315 HIS 315 315 315 HIS HIS B . n 
B 1 316 LEU 316 316 316 LEU LEU B . n 
B 1 317 PHE 317 317 317 PHE PHE B . n 
B 1 318 GLU 318 318 318 GLU GLU B . n 
B 1 319 ILE 319 319 319 ILE ILE B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 PHE 322 322 322 PHE PHE B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 GLY 324 324 324 GLY GLY B . n 
B 1 325 ILE 325 325 325 ILE ILE B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 TRP 327 327 327 TRP TRP B . n 
B 1 328 CYS 328 328 328 CYS CYS B . n 
B 1 329 LEU 329 329 329 LEU LEU B . n 
B 1 330 SER 330 330 330 SER SER B . n 
B 1 331 LEU 331 331 331 LEU LEU B . n 
B 1 332 LEU 332 332 332 LEU LEU B . n 
B 1 333 ALA 333 333 333 ALA ALA B . n 
B 1 334 CYS 334 334 334 CYS CYS B . n 
B 1 335 PHE 335 335 335 PHE PHE B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 PRO 338 338 338 PRO PRO B . n 
B 1 339 ILE 339 339 339 ILE ILE B . n 
B 1 340 SER 340 340 340 SER SER B . n 
B 1 341 VAL 341 341 341 VAL VAL B . n 
B 1 342 ILE 342 342 342 ILE ILE B . n 
B 1 343 PRO 343 343 343 PRO PRO B . n 
B 1 344 THR 344 344 344 THR THR B . n 
B 1 345 TYR 345 345 345 TYR TYR B . n 
B 1 346 VAL 346 346 346 VAL VAL B . n 
B 1 347 TYR 347 347 347 TYR TYR B . n 
B 1 348 PRO 348 348 348 PRO PRO B . n 
B 1 349 LEU 349 349 349 LEU LEU B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 LEU 351 351 351 LEU LEU B . n 
B 1 352 TYR 352 352 352 TYR TYR B . n 
B 1 353 GLY 353 353 353 GLY GLY B . n 
B 1 354 PHE 354 354 354 PHE PHE B . n 
B 1 355 MET 355 355 355 MET MET B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 PHE 357 357 357 PHE PHE B . n 
B 1 358 PHE 358 358 358 PHE PHE B . n 
B 1 359 LEU 359 359 359 LEU LEU B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 ASN 361 361 361 ASN ASN B . n 
B 1 362 PRO 362 362 362 PRO PRO B . n 
B 1 363 THR 363 363 363 THR THR B . n 
B 1 364 LYS 364 364 364 LYS LYS B . n 
B 1 365 THR 365 365 365 THR THR B . n 
B 1 366 PHE 366 366 366 PHE PHE B . n 
B 1 367 TYR 367 367 367 TYR TYR B . n 
B 1 368 TYR 368 368 368 TYR TYR B . n 
B 1 369 LYS 369 369 369 LYS LYS B . n 
B 1 370 SER 370 370 370 SER SER B . n 
B 1 371 ARG 371 371 371 ARG ARG B . n 
B 1 372 PHE 372 372 372 PHE PHE B . n 
B 1 373 TRP 373 373 373 TRP TRP B . n 
B 1 374 LEU 374 374 374 LEU LEU B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 LYS 376 376 376 LYS LYS B . n 
B 1 377 LEU 377 377 377 LEU LEU B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 PHE 379 379 379 PHE PHE B . n 
B 1 380 ARG 380 380 380 ARG ARG B . n 
B 1 381 VAL 381 381 381 VAL VAL B . n 
B 1 382 PHE 382 382 382 PHE PHE B . n 
B 1 383 THR 383 383 383 THR THR B . n 
B 1 384 ALA 384 384 384 ALA ALA B . n 
B 1 385 PRO 385 385 385 PRO PRO B . n 
B 1 386 PHE 386 386 386 PHE PHE B . n 
B 1 387 HIS 387 387 387 HIS HIS B . n 
B 1 388 LYS 388 388 388 LYS LYS B . n 
B 1 389 VAL 389 389 389 VAL VAL B . n 
B 1 390 GLY 390 390 390 GLY GLY B . n 
B 1 391 PHE 391 391 391 PHE PHE B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 ASP 393 393 393 ASP ASP B . n 
B 1 394 PHE 394 394 394 PHE PHE B . n 
B 1 395 TRP 395 395 395 TRP TRP B . n 
B 1 396 LEU 396 396 396 LEU LEU B . n 
B 1 397 ALA 397 397 397 ALA ALA B . n 
B 1 398 ASP 398 398 398 ASP ASP B . n 
B 1 399 GLN 399 399 399 GLN GLN B . n 
B 1 400 LEU 400 400 400 LEU LEU B . n 
B 1 401 ASN 401 401 401 ASN ASN B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 SER 404 404 404 SER SER B . n 
B 1 405 VAL 405 405 405 VAL VAL B . n 
B 1 406 ILE 406 406 406 ILE ILE B . n 
B 1 407 LEU 407 407 407 LEU LEU B . n 
B 1 408 MET 408 408 408 MET MET B . n 
B 1 409 ASP 409 409 409 ASP ASP B . n 
B 1 410 LEU 410 410 410 LEU LEU B . n 
B 1 411 GLU 411 411 411 GLU GLU B . n 
B 1 412 TYR 412 412 412 TYR TYR B . n 
B 1 413 MET 413 413 413 MET MET B . n 
B 1 414 ILE 414 414 414 ILE ILE B . n 
B 1 415 CYS 415 415 415 CYS CYS B . n 
B 1 416 PHE 416 416 416 PHE PHE B . n 
B 1 417 TYR 417 417 417 TYR TYR B . n 
B 1 418 SER 418 418 418 SER SER B . n 
B 1 419 LEU 419 419 419 LEU LEU B . n 
B 1 420 GLU 420 420 420 GLU GLU B . n 
B 1 421 LEU 421 421 421 LEU LEU B . n 
B 1 422 LYS 422 422 422 LYS ALA B . n 
B 1 423 TRP 423 423 ?   ?   ?   B . n 
B 1 424 ASP 424 424 ?   ?   ?   B . n 
B 1 425 GLU 425 425 ?   ?   ?   B . n 
B 1 426 SER 426 426 ?   ?   ?   B . n 
B 1 427 LYS 427 427 ?   ?   ?   B . n 
B 1 428 GLY 428 428 ?   ?   ?   B . n 
B 1 429 LEU 429 429 ?   ?   ?   B . n 
B 1 430 LEU 430 430 ?   ?   ?   B . n 
B 1 431 PRO 431 431 ?   ?   ?   B . n 
B 1 432 ASN 432 432 ?   ?   ?   B . n 
B 1 433 ASN 433 433 ?   ?   ?   B . n 
B 1 434 SER 434 434 ?   ?   ?   B . n 
B 1 435 GLU 435 435 ?   ?   ?   B . n 
B 1 436 GLU 436 436 ?   ?   ?   B . n 
B 1 437 SER 437 437 ?   ?   ?   B . n 
B 1 438 GLY 438 438 ?   ?   ?   B . n 
B 1 439 ILE 439 439 ?   ?   ?   B . n 
B 1 440 CYS 440 440 ?   ?   ?   B . n 
B 1 441 HIS 441 441 ?   ?   ?   B . n 
B 1 442 LYS 442 442 ?   ?   ?   B . n 
B 1 443 TYR 443 443 443 TYR TYR B . n 
B 1 444 THR 444 444 444 THR THR B . n 
B 1 445 TYR 445 445 445 TYR TYR B . n 
B 1 446 GLY 446 446 446 GLY GLY B . n 
B 1 447 VAL 447 447 447 VAL VAL B . n 
B 1 448 ARG 448 448 448 ARG ARG B . n 
B 1 449 ALA 449 449 449 ALA ALA B . n 
B 1 450 ILE 450 450 450 ILE ILE B . n 
B 1 451 VAL 451 451 451 VAL VAL B . n 
B 1 452 GLN 452 452 452 GLN GLN B . n 
B 1 453 CYS 453 453 453 CYS CYS B . n 
B 1 454 ILE 454 454 454 ILE ILE B . n 
B 1 455 PRO 455 455 455 PRO PRO B . n 
B 1 456 ALA 456 456 456 ALA ALA B . n 
B 1 457 TRP 457 457 457 TRP TRP B . n 
B 1 458 LEU 458 458 458 LEU LEU B . n 
B 1 459 ARG 459 459 459 ARG ARG B . n 
B 1 460 PHE 460 460 460 PHE PHE B . n 
B 1 461 ILE 461 461 461 ILE ILE B . n 
B 1 462 GLN 462 462 462 GLN GLN B . n 
B 1 463 CYS 463 463 463 CYS CYS B . n 
B 1 464 LEU 464 464 464 LEU LEU B . n 
B 1 465 ARG 465 465 465 ARG ARG B . n 
B 1 466 ARG 466 466 466 ARG ARG B . n 
B 1 467 TYR 467 467 467 TYR TYR B . n 
B 1 468 ARG 468 468 468 ARG ARG B . n 
B 1 469 ASP 469 469 469 ASP ASP B . n 
B 1 470 THR 470 470 470 THR THR B . n 
B 1 471 LYS 471 471 471 LYS LYS B . n 
B 1 472 ARG 472 472 472 ARG ARG B . n 
B 1 473 ALA 473 473 473 ALA ALA B . n 
B 1 474 PHE 474 474 474 PHE PHE B . n 
B 1 475 PRO 475 475 475 PRO PRO B . n 
B 1 476 HIS 476 476 476 HIS HIS B . n 
B 1 477 LEU 477 477 477 LEU LEU B . n 
B 1 478 VAL 478 478 478 VAL VAL B . n 
B 1 479 ASN 479 479 479 ASN ASN B . n 
B 1 480 ALA 480 480 480 ALA ALA B . n 
B 1 481 GLY 481 481 481 GLY GLY B . n 
B 1 482 LYS 482 482 482 LYS LYS B . n 
B 1 483 TYR 483 483 483 TYR TYR B . n 
B 1 484 SER 484 484 484 SER SER B . n 
B 1 485 THR 485 485 485 THR THR B . n 
B 1 486 THR 486 486 486 THR THR B . n 
B 1 487 PHE 487 487 487 PHE PHE B . n 
B 1 488 PHE 488 488 488 PHE PHE B . n 
B 1 489 MET 489 489 489 MET MET B . n 
B 1 490 VAL 490 490 490 VAL VAL B . n 
B 1 491 THR 491 491 491 THR THR B . n 
B 1 492 PHE 492 492 492 PHE PHE B . n 
B 1 493 ALA 493 493 493 ALA ALA B . n 
B 1 494 ALA 494 494 494 ALA ALA B . n 
B 1 495 LEU 495 495 495 LEU LEU B . n 
B 1 496 TYR 496 496 496 TYR TYR B . n 
B 1 497 SER 497 497 497 SER SER B . n 
B 1 498 THR 498 498 498 THR THR B . n 
B 1 499 HIS 499 499 499 HIS HIS B . n 
B 1 500 LYS 500 500 500 LYS LYS B . n 
B 1 501 GLU 501 501 501 GLU GLU B . n 
B 1 502 ARG 502 502 502 ARG ARG B . n 
B 1 503 GLY 503 503 503 GLY GLY B . n 
B 1 504 HIS 504 504 504 HIS HIS B . n 
B 1 505 SER 505 505 505 SER SER B . n 
B 1 506 ASP 506 506 506 ASP ASP B . n 
B 1 507 THR 507 507 507 THR THR B . n 
B 1 508 MET 508 508 508 MET MET B . n 
B 1 509 VAL 509 509 509 VAL VAL B . n 
B 1 510 PHE 510 510 510 PHE PHE B . n 
B 1 511 PHE 511 511 511 PHE PHE B . n 
B 1 512 TYR 512 512 512 TYR TYR B . n 
B 1 513 LEU 513 513 513 LEU LEU B . n 
B 1 514 TRP 514 514 514 TRP TRP B . n 
B 1 515 ILE 515 515 515 ILE ILE B . n 
B 1 516 VAL 516 516 516 VAL VAL B . n 
B 1 517 PHE 517 517 517 PHE PHE B . n 
B 1 518 TYR 518 518 518 TYR TYR B . n 
B 1 519 ILE 519 519 519 ILE ILE B . n 
B 1 520 ILE 520 520 520 ILE ILE B . n 
B 1 521 SER 521 521 521 SER SER B . n 
B 1 522 SER 522 522 522 SER SER B . n 
B 1 523 CYS 523 523 523 CYS CYS B . n 
B 1 524 TYR 524 524 524 TYR TYR B . n 
B 1 525 THR 525 525 525 THR THR B . n 
B 1 526 LEU 526 526 526 LEU LEU B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 TRP 528 528 528 TRP TRP B . n 
B 1 529 ASP 529 529 529 ASP ASP B . n 
B 1 530 LEU 530 530 530 LEU LEU B . n 
B 1 531 LYS 531 531 531 LYS LYS B . n 
B 1 532 MET 532 532 532 MET MET B . n 
B 1 533 ASP 533 533 533 ASP ASP B . n 
B 1 534 TRP 534 534 534 TRP TRP B . n 
B 1 535 GLY 535 535 535 GLY GLY B . n 
B 1 536 LEU 536 536 536 LEU LEU B . n 
B 1 537 PHE 537 537 537 PHE PHE B . n 
B 1 538 ASP 538 538 538 ASP ASP B . n 
B 1 539 LYS 539 539 539 LYS LYS B . n 
B 1 540 ASN 540 540 540 ASN ASN B . n 
B 1 541 ALA 541 541 541 ALA ALA B . n 
B 1 542 GLY 542 542 542 GLY GLY B . n 
B 1 543 GLU 543 543 543 GLU GLU B . n 
B 1 544 ASN 544 544 544 ASN ASN B . n 
B 1 545 THR 545 545 545 THR THR B . n 
B 1 546 PHE 546 546 546 PHE PHE B . n 
B 1 547 LEU 547 547 547 LEU LEU B . n 
B 1 548 ARG 548 548 548 ARG ARG B . n 
B 1 549 GLU 549 549 549 GLU GLU B . n 
B 1 550 GLU 550 550 550 GLU GLU B . n 
B 1 551 ILE 551 551 551 ILE ILE B . n 
B 1 552 VAL 552 552 552 VAL VAL B . n 
B 1 553 TYR 553 553 553 TYR TYR B . n 
B 1 554 PRO 554 554 554 PRO PRO B . n 
B 1 555 GLN 555 555 555 GLN GLN B . n 
B 1 556 LYS 556 556 556 LYS LYS B . n 
B 1 557 ALA 557 557 557 ALA ALA B . n 
B 1 558 TYR 558 558 558 TYR TYR B . n 
B 1 559 TYR 559 559 559 TYR TYR B . n 
B 1 560 TYR 560 560 560 TYR TYR B . n 
B 1 561 CYS 561 561 561 CYS CYS B . n 
B 1 562 ALA 562 562 562 ALA ALA B . n 
B 1 563 ILE 563 563 563 ILE ILE B . n 
B 1 564 ILE 564 564 564 ILE ILE B . n 
B 1 565 GLU 565 565 565 GLU GLU B . n 
B 1 566 ASP 566 566 566 ASP ASP B . n 
B 1 567 VAL 567 567 567 VAL VAL B . n 
B 1 568 ILE 568 568 568 ILE ILE B . n 
B 1 569 LEU 569 569 569 LEU LEU B . n 
B 1 570 ARG 570 570 570 ARG ARG B . n 
B 1 571 PHE 571 571 571 PHE PHE B . n 
B 1 572 ALA 572 572 572 ALA ALA B . n 
B 1 573 TRP 573 573 573 TRP TRP B . n 
B 1 574 THR 574 574 574 THR THR B . n 
B 1 575 ILE 575 575 575 ILE ILE B . n 
B 1 576 GLN 576 576 576 GLN GLN B . n 
B 1 577 ILE 577 577 577 ILE ILE B . n 
B 1 578 SER 578 578 578 SER SER B . n 
B 1 579 ILE 579 579 579 ILE ILE B . n 
B 1 580 THR 580 580 580 THR THR B . n 
B 1 581 SER 581 581 581 SER SER B . n 
B 1 582 THR 582 582 582 THR THR B . n 
B 1 583 THR 583 583 583 THR THR B . n 
B 1 584 LEU 584 584 584 LEU LEU B . n 
B 1 585 LEU 585 585 585 LEU LEU B . n 
B 1 586 PRO 586 586 586 PRO PRO B . n 
B 1 587 HIS 587 587 587 HIS HIS B . n 
B 1 588 SER 588 588 588 SER SER B . n 
B 1 589 GLY 589 589 589 GLY GLY B . n 
B 1 590 ASP 590 590 590 ASP ASP B . n 
B 1 591 ILE 591 591 591 ILE ILE B . n 
B 1 592 ILE 592 592 592 ILE ILE B . n 
B 1 593 ALA 593 593 593 ALA ALA B . n 
B 1 594 THR 594 594 594 THR THR B . n 
B 1 595 VAL 595 595 595 VAL VAL B . n 
B 1 596 PHE 596 596 596 PHE PHE B . n 
B 1 597 ALA 597 597 597 ALA ALA B . n 
B 1 598 PRO 598 598 598 PRO PRO B . n 
B 1 599 LEU 599 599 599 LEU LEU B . n 
B 1 600 GLU 600 600 600 GLU GLU B . n 
B 1 601 VAL 601 601 601 VAL VAL B . n 
B 1 602 PHE 602 602 602 PHE PHE B . n 
B 1 603 ARG 603 603 603 ARG ARG B . n 
B 1 604 ARG 604 604 604 ARG ARG B . n 
B 1 605 PHE 605 605 605 PHE PHE B . n 
B 1 606 VAL 606 606 606 VAL VAL B . n 
B 1 607 TRP 607 607 607 TRP TRP B . n 
B 1 608 ASN 608 608 608 ASN ASN B . n 
B 1 609 PHE 609 609 609 PHE PHE B . n 
B 1 610 PHE 610 610 610 PHE PHE B . n 
B 1 611 ARG 611 611 611 ARG ARG B . n 
B 1 612 LEU 612 612 612 LEU LEU B . n 
B 1 613 GLU 613 613 613 GLU GLU B . n 
B 1 614 ASN 614 614 614 ASN ASN B . n 
B 1 615 GLU 615 615 615 GLU GLU B . n 
B 1 616 HIS 616 616 616 HIS HIS B . n 
B 1 617 LEU 617 617 617 LEU LEU B . n 
B 1 618 ASN 618 618 618 ASN ASN B . n 
B 1 619 ASN 619 619 619 ASN ASN B . n 
B 1 620 CYS 620 620 620 CYS CYS B . n 
B 1 621 GLY 621 621 621 GLY GLY B . n 
B 1 622 GLU 622 622 622 GLU GLU B . n 
B 1 623 PHE 623 623 623 PHE PHE B . n 
B 1 624 ARG 624 624 624 ARG ARG B . n 
B 1 625 ALA 625 625 625 ALA ALA B . n 
B 1 626 VAL 626 626 ?   ?   ?   B . n 
B 1 627 ARG 627 627 ?   ?   ?   B . n 
B 1 628 ASP 628 628 ?   ?   ?   B . n 
B 1 629 ILE 629 629 ?   ?   ?   B . n 
B 1 630 SER 630 630 ?   ?   ?   B . n 
B 1 631 VAL 631 631 ?   ?   ?   B . n 
B 1 632 ALA 632 632 ?   ?   ?   B . n 
B 1 633 PRO 633 633 ?   ?   ?   B . n 
B 1 634 LEU 634 634 ?   ?   ?   B . n 
B 1 635 ASN 635 635 ?   ?   ?   B . n 
B 1 636 ALA 636 636 ?   ?   ?   B . n 
B 1 637 ASP 637 637 ?   ?   ?   B . n 
B 1 638 ASP 638 638 ?   ?   ?   B . n 
B 1 639 GLN 639 639 ?   ?   ?   B . n 
B 1 640 THR 640 640 ?   ?   ?   B . n 
B 1 641 LEU 641 641 ?   ?   ?   B . n 
B 1 642 LEU 642 642 ?   ?   ?   B . n 
B 1 643 GLU 643 643 ?   ?   ?   B . n 
B 1 644 GLN 644 644 ?   ?   ?   B . n 
B 1 645 MET 645 645 ?   ?   ?   B . n 
B 1 646 MET 646 646 ?   ?   ?   B . n 
B 1 647 ASP 647 647 ?   ?   ?   B . n 
B 1 648 GLN 648 648 ?   ?   ?   B . n 
B 1 649 ASP 649 649 ?   ?   ?   B . n 
B 1 650 ASP 650 650 ?   ?   ?   B . n 
B 1 651 GLY 651 651 ?   ?   ?   B . n 
B 1 652 VAL 652 652 ?   ?   ?   B . n 
B 1 653 ARG 653 653 ?   ?   ?   B . n 
B 1 654 ASN 654 654 ?   ?   ?   B . n 
B 1 655 ARG 655 655 ?   ?   ?   B . n 
B 1 656 GLN 656 656 ?   ?   ?   B . n 
B 1 657 LYS 657 657 ?   ?   ?   B . n 
B 1 658 ASN 658 658 ?   ?   ?   B . n 
B 1 659 ARG 659 659 ?   ?   ?   B . n 
B 1 660 SER 660 660 ?   ?   ?   B . n 
B 1 661 TRP 661 661 ?   ?   ?   B . n 
B 1 662 LYS 662 662 ?   ?   ?   B . n 
B 1 663 TYR 663 663 ?   ?   ?   B . n 
B 1 664 ASN 664 664 ?   ?   ?   B . n 
B 1 665 GLN 665 665 ?   ?   ?   B . n 
B 1 666 SER 666 666 ?   ?   ?   B . n 
B 1 667 ILE 667 667 ?   ?   ?   B . n 
B 1 668 SER 668 668 ?   ?   ?   B . n 
B 1 669 LEU 669 669 ?   ?   ?   B . n 
B 1 670 ARG 670 670 ?   ?   ?   B . n 
B 1 671 ARG 671 671 ?   ?   ?   B . n 
B 1 672 PRO 672 672 ?   ?   ?   B . n 
B 1 673 ARG 673 673 ?   ?   ?   B . n 
B 1 674 LEU 674 674 ?   ?   ?   B . n 
B 1 675 ALA 675 675 ?   ?   ?   B . n 
B 1 676 SER 676 676 ?   ?   ?   B . n 
B 1 677 GLN 677 677 ?   ?   ?   B . n 
B 1 678 SER 678 678 ?   ?   ?   B . n 
B 1 679 LYS 679 679 ?   ?   ?   B . n 
B 1 680 ALA 680 680 ?   ?   ?   B . n 
B 1 681 ARG 681 681 ?   ?   ?   B . n 
B 1 682 ASP 682 682 ?   ?   ?   B . n 
B 1 683 THR 683 683 ?   ?   ?   B . n 
B 1 684 LYS 684 684 ?   ?   ?   B . n 
B 1 685 VAL 685 685 ?   ?   ?   B . n 
B 1 686 LEU 686 686 ?   ?   ?   B . n 
B 1 687 ILE 687 687 ?   ?   ?   B . n 
B 1 688 GLU 688 688 ?   ?   ?   B . n 
B 1 689 ASP 689 689 ?   ?   ?   B . n 
B 1 690 THR 690 690 ?   ?   ?   B . n 
B 1 691 ASP 691 691 ?   ?   ?   B . n 
B 1 692 ASP 692 692 ?   ?   ?   B . n 
B 1 693 GLU 693 693 ?   ?   ?   B . n 
B 1 694 ALA 694 694 ?   ?   ?   B . n 
B 1 695 ASN 695 695 ?   ?   ?   B . n 
B 1 696 THR 696 696 ?   ?   ?   B . n 
B 1 697 GLU 697 697 ?   ?   ?   B . n 
B 1 698 ASN 698 698 ?   ?   ?   B . n 
B 1 699 LEU 699 699 ?   ?   ?   B . n 
B 1 700 TYR 700 700 ?   ?   ?   B . n 
B 1 701 PHE 701 701 ?   ?   ?   B . n 
B 1 702 GLN 702 702 ?   ?   ?   B . n 
B 1 703 GLY 703 703 ?   ?   ?   B . n 
B 1 704 HIS 704 704 ?   ?   ?   B . n 
B 1 705 HIS 705 705 ?   ?   ?   B . n 
B 1 706 HIS 706 706 ?   ?   ?   B . n 
B 1 707 HIS 707 707 ?   ?   ?   B . n 
B 1 708 HIS 708 708 ?   ?   ?   B . n 
B 1 709 HIS 709 709 ?   ?   ?   B . n 
B 1 710 HIS 710 710 ?   ?   ?   B . n 
B 1 711 HIS 711 711 ?   ?   ?   B . n 
B 1 712 SER 712 712 ?   ?   ?   B . n 
B 1 713 GLY 713 713 ?   ?   ?   B . n 
B 1 714 ALA 714 714 ?   ?   ?   B . n 
B 1 715 ALA 715 715 ?   ?   ?   B . n 
B 1 716 ALA 716 716 ?   ?   ?   B . n 
B 1 717 TRP 717 717 ?   ?   ?   B . n 
B 1 718 SER 718 718 ?   ?   ?   B . n 
B 1 719 HIS 719 719 ?   ?   ?   B . n 
B 1 720 PRO 720 720 ?   ?   ?   B . n 
B 1 721 GLN 721 721 ?   ?   ?   B . n 
B 1 722 PHE 722 722 ?   ?   ?   B . n 
B 1 723 GLU 723 723 ?   ?   ?   B . n 
B 1 724 LYS 724 724 ?   ?   ?   B . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A LYS 422 ? CG ? A LYS 422 CG 
2 1 Y 1 A LYS 422 ? CD ? A LYS 422 CD 
3 1 Y 1 A LYS 422 ? CE ? A LYS 422 CE 
4 1 Y 1 A LYS 422 ? NZ ? A LYS 422 NZ 
5 1 Y 1 B LYS 422 ? CG ? B LYS 422 CG 
6 1 Y 1 B LYS 422 ? CD ? B LYS 422 CD 
7 1 Y 1 B LYS 422 ? CE ? B LYS 422 CE 
8 1 Y 1 B LYS 422 ? NZ ? B LYS 422 NZ 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CL0 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CL0 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CL0 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9CL0 
_struct.title                        'Cryo-EM structure of human XPR1 in presence of inorganic phosphate and phytic acid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CL0 
_struct_keywords.text            'Ion channel, phosphate transport, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S53A1_HUMAN 
_struct_ref.pdbx_db_accession          Q9UBH6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CL0 A 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
2 1 9CL0 B 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CL0 GLU A 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 1  
1 9CL0 ASN A 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 2  
1 9CL0 LEU A 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 3  
1 9CL0 TYR A 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 4  
1 9CL0 PHE A 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 5  
1 9CL0 GLN A 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 6  
1 9CL0 GLY A 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 7  
1 9CL0 HIS A 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 8  
1 9CL0 HIS A 705 ? UNP Q9UBH6 ? ? 'expression tag' 705 9  
1 9CL0 HIS A 706 ? UNP Q9UBH6 ? ? 'expression tag' 706 10 
1 9CL0 HIS A 707 ? UNP Q9UBH6 ? ? 'expression tag' 707 11 
1 9CL0 HIS A 708 ? UNP Q9UBH6 ? ? 'expression tag' 708 12 
1 9CL0 HIS A 709 ? UNP Q9UBH6 ? ? 'expression tag' 709 13 
1 9CL0 HIS A 710 ? UNP Q9UBH6 ? ? 'expression tag' 710 14 
1 9CL0 HIS A 711 ? UNP Q9UBH6 ? ? 'expression tag' 711 15 
1 9CL0 SER A 712 ? UNP Q9UBH6 ? ? 'expression tag' 712 16 
1 9CL0 GLY A 713 ? UNP Q9UBH6 ? ? 'expression tag' 713 17 
1 9CL0 ALA A 714 ? UNP Q9UBH6 ? ? 'expression tag' 714 18 
1 9CL0 ALA A 715 ? UNP Q9UBH6 ? ? 'expression tag' 715 19 
1 9CL0 ALA A 716 ? UNP Q9UBH6 ? ? 'expression tag' 716 20 
1 9CL0 TRP A 717 ? UNP Q9UBH6 ? ? 'expression tag' 717 21 
1 9CL0 SER A 718 ? UNP Q9UBH6 ? ? 'expression tag' 718 22 
1 9CL0 HIS A 719 ? UNP Q9UBH6 ? ? 'expression tag' 719 23 
1 9CL0 PRO A 720 ? UNP Q9UBH6 ? ? 'expression tag' 720 24 
1 9CL0 GLN A 721 ? UNP Q9UBH6 ? ? 'expression tag' 721 25 
1 9CL0 PHE A 722 ? UNP Q9UBH6 ? ? 'expression tag' 722 26 
1 9CL0 GLU A 723 ? UNP Q9UBH6 ? ? 'expression tag' 723 27 
1 9CL0 LYS A 724 ? UNP Q9UBH6 ? ? 'expression tag' 724 28 
2 9CL0 GLU B 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 29 
2 9CL0 ASN B 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 30 
2 9CL0 LEU B 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 31 
2 9CL0 TYR B 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 32 
2 9CL0 PHE B 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 33 
2 9CL0 GLN B 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 34 
2 9CL0 GLY B 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 35 
2 9CL0 HIS B 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 36 
2 9CL0 HIS B 705 ? UNP Q9UBH6 ? ? 'expression tag' 705 37 
2 9CL0 HIS B 706 ? UNP Q9UBH6 ? ? 'expression tag' 706 38 
2 9CL0 HIS B 707 ? UNP Q9UBH6 ? ? 'expression tag' 707 39 
2 9CL0 HIS B 708 ? UNP Q9UBH6 ? ? 'expression tag' 708 40 
2 9CL0 HIS B 709 ? UNP Q9UBH6 ? ? 'expression tag' 709 41 
2 9CL0 HIS B 710 ? UNP Q9UBH6 ? ? 'expression tag' 710 42 
2 9CL0 HIS B 711 ? UNP Q9UBH6 ? ? 'expression tag' 711 43 
2 9CL0 SER B 712 ? UNP Q9UBH6 ? ? 'expression tag' 712 44 
2 9CL0 GLY B 713 ? UNP Q9UBH6 ? ? 'expression tag' 713 45 
2 9CL0 ALA B 714 ? UNP Q9UBH6 ? ? 'expression tag' 714 46 
2 9CL0 ALA B 715 ? UNP Q9UBH6 ? ? 'expression tag' 715 47 
2 9CL0 ALA B 716 ? UNP Q9UBH6 ? ? 'expression tag' 716 48 
2 9CL0 TRP B 717 ? UNP Q9UBH6 ? ? 'expression tag' 717 49 
2 9CL0 SER B 718 ? UNP Q9UBH6 ? ? 'expression tag' 718 50 
2 9CL0 HIS B 719 ? UNP Q9UBH6 ? ? 'expression tag' 719 51 
2 9CL0 PRO B 720 ? UNP Q9UBH6 ? ? 'expression tag' 720 52 
2 9CL0 GLN B 721 ? UNP Q9UBH6 ? ? 'expression tag' 721 53 
2 9CL0 PHE B 722 ? UNP Q9UBH6 ? ? 'expression tag' 722 54 
2 9CL0 GLU B 723 ? UNP Q9UBH6 ? ? 'expression tag' 723 55 
2 9CL0 LYS B 724 ? UNP Q9UBH6 ? ? 'expression tag' 724 56 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 231 ? PHE A 257 ? ALA A 231 PHE A 257 1 ? 27 
HELX_P HELX_P2  AA2 ILE A 265 ? GLY A 296 ? ILE A 265 GLY A 296 1 ? 32 
HELX_P HELX_P3  AA3 ASN A 298 ? PHE A 303 ? ASN A 298 PHE A 303 1 ? 6  
HELX_P HELX_P4  AA4 SER A 312 ? ALA A 337 ? SER A 312 ALA A 337 1 ? 26 
HELX_P HELX_P5  AA5 VAL A 346 ? ASN A 361 ? VAL A 346 ASN A 361 1 ? 16 
HELX_P HELX_P6  AA6 TYR A 367 ? THR A 383 ? TYR A 367 THR A 383 1 ? 17 
HELX_P HELX_P7  AA7 ALA A 384 ? HIS A 387 ? ALA A 384 HIS A 387 5 ? 4  
HELX_P HELX_P8  AA8 GLY A 390 ? SER A 402 ? GLY A 390 SER A 402 1 ? 13 
HELX_P HELX_P9  AA9 LEU A 403 ? LEU A 419 ? LEU A 403 LEU A 419 1 ? 17 
HELX_P HELX_P10 AB1 TYR A 445 ? LYS A 471 ? TYR A 445 LYS A 471 1 ? 27 
HELX_P HELX_P11 AB2 ARG A 472 ? ARG A 502 ? ARG A 472 ARG A 502 1 ? 31 
HELX_P HELX_P12 AB3 ASP A 506 ? MET A 532 ? ASP A 506 MET A 532 1 ? 27 
HELX_P HELX_P13 AB4 GLN A 555 ? SER A 581 ? GLN A 555 SER A 581 1 ? 27 
HELX_P HELX_P14 AB5 SER A 588 ? ASN A 619 ? SER A 588 ASN A 619 1 ? 32 
HELX_P HELX_P15 AB6 TRP B 232 ? PHE B 257 ? TRP B 232 PHE B 257 1 ? 26 
HELX_P HELX_P16 AB7 ILE B 265 ? GLY B 296 ? ILE B 265 GLY B 296 1 ? 32 
HELX_P HELX_P17 AB8 ASN B 298 ? PHE B 303 ? ASN B 298 PHE B 303 1 ? 6  
HELX_P HELX_P18 AB9 SER B 312 ? ALA B 337 ? SER B 312 ALA B 337 1 ? 26 
HELX_P HELX_P19 AC1 VAL B 346 ? ASN B 361 ? VAL B 346 ASN B 361 1 ? 16 
HELX_P HELX_P20 AC2 TYR B 367 ? THR B 383 ? TYR B 367 THR B 383 1 ? 17 
HELX_P HELX_P21 AC3 ALA B 384 ? HIS B 387 ? ALA B 384 HIS B 387 5 ? 4  
HELX_P HELX_P22 AC4 GLY B 390 ? SER B 402 ? GLY B 390 SER B 402 1 ? 13 
HELX_P HELX_P23 AC5 LEU B 403 ? LEU B 419 ? LEU B 403 LEU B 419 1 ? 17 
HELX_P HELX_P24 AC6 TYR B 445 ? LYS B 471 ? TYR B 445 LYS B 471 1 ? 27 
HELX_P HELX_P25 AC7 ARG B 472 ? ARG B 502 ? ARG B 472 ARG B 502 1 ? 31 
HELX_P HELX_P26 AC8 ASP B 506 ? MET B 532 ? ASP B 506 MET B 532 1 ? 27 
HELX_P HELX_P27 AC9 GLN B 555 ? SER B 581 ? GLN B 555 SER B 581 1 ? 27 
HELX_P HELX_P28 AD1 SER B 588 ? ASN B 619 ? SER B 588 ASN B 619 1 ? 32 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 474 A . ? PHE 474 A PRO 475 A ? PRO 475 A 1 -0.57 
2 PHE 474 B . ? PHE 474 B PRO 475 B ? PRO 475 B 1 -0.57 
# 
_pdbx_entry_details.entry_id                   9CL0 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NZ A LYS 258 ? ? CE1 A PHE 336 ? ? 1.78 
2 1 NZ B LYS 258 ? ? CE1 B PHE 336 ? ? 1.78 
3 1 NZ B LYS 258 ? ? CZ  B PHE 336 ? ? 2.03 
4 1 NZ A LYS 258 ? ? CZ  A PHE 336 ? ? 2.03 
5 1 CD B LYS 258 ? ? CE1 B PHE 336 ? ? 2.10 
6 1 CD A LYS 258 ? ? CE1 A PHE 336 ? ? 2.10 
7 1 O  B HIS 499 ? ? OG1 B THR 507 ? ? 2.13 
8 1 O  A HIS 499 ? ? OG1 A THR 507 ? ? 2.13 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CB A PHE 386 ? ? CA A PHE 386 ? ? C  A PHE 386 ? ? 80.69  110.40 -29.71 2.00 N 
2  1 N  A PHE 386 ? ? CA A PHE 386 ? ? C  A PHE 386 ? ? 146.86 111.00 35.86  2.70 N 
3  1 CB A HIS 387 ? ? CA A HIS 387 ? ? C  A HIS 387 ? ? 124.38 110.40 13.98  2.00 N 
4  1 N  A HIS 387 ? ? CA A HIS 387 ? ? CB A HIS 387 ? ? 90.29  110.60 -20.31 1.80 N 
5  1 N  A HIS 387 ? ? CA A HIS 387 ? ? C  A HIS 387 ? ? 80.56  111.00 -30.44 2.70 N 
6  1 CB A LEU 421 ? ? CA A LEU 421 ? ? C  A LEU 421 ? ? 85.04  110.20 -25.16 1.90 N 
7  1 N  A LEU 421 ? ? CA A LEU 421 ? ? C  A LEU 421 ? ? 150.09 111.00 39.09  2.70 N 
8  1 N  A LYS 422 ? ? CA A LYS 422 ? ? CB A LYS 422 ? ? 122.96 110.60 12.36  1.80 N 
9  1 CB A ARG 468 ? ? CA A ARG 468 ? ? C  A ARG 468 ? ? 92.86  110.40 -17.54 2.00 N 
10 1 CB B PHE 386 ? ? CA B PHE 386 ? ? C  B PHE 386 ? ? 80.69  110.40 -29.71 2.00 N 
11 1 N  B PHE 386 ? ? CA B PHE 386 ? ? C  B PHE 386 ? ? 146.86 111.00 35.86  2.70 N 
12 1 CB B HIS 387 ? ? CA B HIS 387 ? ? C  B HIS 387 ? ? 124.38 110.40 13.98  2.00 N 
13 1 N  B HIS 387 ? ? CA B HIS 387 ? ? CB B HIS 387 ? ? 90.29  110.60 -20.31 1.80 N 
14 1 N  B HIS 387 ? ? CA B HIS 387 ? ? C  B HIS 387 ? ? 80.56  111.00 -30.44 2.70 N 
15 1 CB B LEU 421 ? ? CA B LEU 421 ? ? C  B LEU 421 ? ? 85.04  110.20 -25.16 1.90 N 
16 1 N  B LEU 421 ? ? CA B LEU 421 ? ? C  B LEU 421 ? ? 150.09 111.00 39.09  2.70 N 
17 1 N  B LYS 422 ? ? CA B LYS 422 ? ? CB B LYS 422 ? ? 122.96 110.60 12.36  1.80 N 
18 1 CB B ARG 468 ? ? CA B ARG 468 ? ? C  B ARG 468 ? ? 92.86  110.40 -17.54 2.00 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE A 257 ? ? -100.29 -76.83  
2  1 GLU A 260 ? ? 55.24   -132.66 
3  1 ARG A 263 ? ? 75.44   130.44  
4  1 ALA A 337 ? ? 54.72   73.01   
5  1 LYS A 364 ? ? -93.83  58.83   
6  1 THR A 383 ? ? -95.46  53.48   
7  1 LEU A 536 ? ? -100.17 -164.67 
8  1 PHE A 537 ? ? 48.57   28.85   
9  1 PHE A 546 ? ? 66.26   -1.41   
10 1 PHE B 257 ? ? -100.29 -76.83  
11 1 GLU B 260 ? ? 55.24   -132.66 
12 1 ARG B 263 ? ? 75.44   130.44  
13 1 ALA B 337 ? ? 54.72   73.01   
14 1 LYS B 364 ? ? -93.83  58.83   
15 1 THR B 383 ? ? -95.46  53.48   
16 1 LEU B 536 ? ? -100.17 -164.67 
17 1 PHE B 537 ? ? 48.57   28.85   
18 1 PHE B 546 ? ? 66.26   -1.41   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 263 ? ? 0.165 'SIDE CHAIN' 
2 1 ARG A 308 ? ? 0.089 'SIDE CHAIN' 
3 1 ARG A 468 ? ? 0.163 'SIDE CHAIN' 
4 1 ARG B 263 ? ? 0.165 'SIDE CHAIN' 
5 1 ARG B 308 ? ? 0.089 'SIDE CHAIN' 
6 1 ARG B 468 ? ? 0.163 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9CL0 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9CL0 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               536955 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Homodimeric complex of full-length human XPR1 in detergents' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9CL0 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              9CL0 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9CL0 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9CL0 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A LYS 2   ? A LYS 2   
3   1 Y 1 A PHE 3   ? A PHE 3   
4   1 Y 1 A ALA 4   ? A ALA 4   
5   1 Y 1 A GLU 5   ? A GLU 5   
6   1 Y 1 A HIS 6   ? A HIS 6   
7   1 Y 1 A LEU 7   ? A LEU 7   
8   1 Y 1 A SER 8   ? A SER 8   
9   1 Y 1 A ALA 9   ? A ALA 9   
10  1 Y 1 A HIS 10  ? A HIS 10  
11  1 Y 1 A ILE 11  ? A ILE 11  
12  1 Y 1 A THR 12  ? A THR 12  
13  1 Y 1 A PRO 13  ? A PRO 13  
14  1 Y 1 A GLU 14  ? A GLU 14  
15  1 Y 1 A TRP 15  ? A TRP 15  
16  1 Y 1 A ARG 16  ? A ARG 16  
17  1 Y 1 A LYS 17  ? A LYS 17  
18  1 Y 1 A GLN 18  ? A GLN 18  
19  1 Y 1 A TYR 19  ? A TYR 19  
20  1 Y 1 A ILE 20  ? A ILE 20  
21  1 Y 1 A GLN 21  ? A GLN 21  
22  1 Y 1 A TYR 22  ? A TYR 22  
23  1 Y 1 A GLU 23  ? A GLU 23  
24  1 Y 1 A ALA 24  ? A ALA 24  
25  1 Y 1 A PHE 25  ? A PHE 25  
26  1 Y 1 A LYS 26  ? A LYS 26  
27  1 Y 1 A ASP 27  ? A ASP 27  
28  1 Y 1 A MET 28  ? A MET 28  
29  1 Y 1 A LEU 29  ? A LEU 29  
30  1 Y 1 A TYR 30  ? A TYR 30  
31  1 Y 1 A SER 31  ? A SER 31  
32  1 Y 1 A ALA 32  ? A ALA 32  
33  1 Y 1 A GLN 33  ? A GLN 33  
34  1 Y 1 A ASP 34  ? A ASP 34  
35  1 Y 1 A GLN 35  ? A GLN 35  
36  1 Y 1 A ALA 36  ? A ALA 36  
37  1 Y 1 A PRO 37  ? A PRO 37  
38  1 Y 1 A SER 38  ? A SER 38  
39  1 Y 1 A VAL 39  ? A VAL 39  
40  1 Y 1 A GLU 40  ? A GLU 40  
41  1 Y 1 A VAL 41  ? A VAL 41  
42  1 Y 1 A THR 42  ? A THR 42  
43  1 Y 1 A ASP 43  ? A ASP 43  
44  1 Y 1 A GLU 44  ? A GLU 44  
45  1 Y 1 A ASP 45  ? A ASP 45  
46  1 Y 1 A THR 46  ? A THR 46  
47  1 Y 1 A VAL 47  ? A VAL 47  
48  1 Y 1 A LYS 48  ? A LYS 48  
49  1 Y 1 A ARG 49  ? A ARG 49  
50  1 Y 1 A TYR 50  ? A TYR 50  
51  1 Y 1 A PHE 51  ? A PHE 51  
52  1 Y 1 A ALA 52  ? A ALA 52  
53  1 Y 1 A LYS 53  ? A LYS 53  
54  1 Y 1 A PHE 54  ? A PHE 54  
55  1 Y 1 A GLU 55  ? A GLU 55  
56  1 Y 1 A GLU 56  ? A GLU 56  
57  1 Y 1 A LYS 57  ? A LYS 57  
58  1 Y 1 A PHE 58  ? A PHE 58  
59  1 Y 1 A PHE 59  ? A PHE 59  
60  1 Y 1 A GLN 60  ? A GLN 60  
61  1 Y 1 A THR 61  ? A THR 61  
62  1 Y 1 A CYS 62  ? A CYS 62  
63  1 Y 1 A GLU 63  ? A GLU 63  
64  1 Y 1 A LYS 64  ? A LYS 64  
65  1 Y 1 A GLU 65  ? A GLU 65  
66  1 Y 1 A LEU 66  ? A LEU 66  
67  1 Y 1 A ALA 67  ? A ALA 67  
68  1 Y 1 A LYS 68  ? A LYS 68  
69  1 Y 1 A ILE 69  ? A ILE 69  
70  1 Y 1 A ASN 70  ? A ASN 70  
71  1 Y 1 A THR 71  ? A THR 71  
72  1 Y 1 A PHE 72  ? A PHE 72  
73  1 Y 1 A TYR 73  ? A TYR 73  
74  1 Y 1 A SER 74  ? A SER 74  
75  1 Y 1 A GLU 75  ? A GLU 75  
76  1 Y 1 A LYS 76  ? A LYS 76  
77  1 Y 1 A LEU 77  ? A LEU 77  
78  1 Y 1 A ALA 78  ? A ALA 78  
79  1 Y 1 A GLU 79  ? A GLU 79  
80  1 Y 1 A ALA 80  ? A ALA 80  
81  1 Y 1 A GLN 81  ? A GLN 81  
82  1 Y 1 A ARG 82  ? A ARG 82  
83  1 Y 1 A ARG 83  ? A ARG 83  
84  1 Y 1 A PHE 84  ? A PHE 84  
85  1 Y 1 A ALA 85  ? A ALA 85  
86  1 Y 1 A THR 86  ? A THR 86  
87  1 Y 1 A LEU 87  ? A LEU 87  
88  1 Y 1 A GLN 88  ? A GLN 88  
89  1 Y 1 A ASN 89  ? A ASN 89  
90  1 Y 1 A GLU 90  ? A GLU 90  
91  1 Y 1 A LEU 91  ? A LEU 91  
92  1 Y 1 A GLN 92  ? A GLN 92  
93  1 Y 1 A SER 93  ? A SER 93  
94  1 Y 1 A SER 94  ? A SER 94  
95  1 Y 1 A LEU 95  ? A LEU 95  
96  1 Y 1 A ASP 96  ? A ASP 96  
97  1 Y 1 A ALA 97  ? A ALA 97  
98  1 Y 1 A GLN 98  ? A GLN 98  
99  1 Y 1 A LYS 99  ? A LYS 99  
100 1 Y 1 A GLU 100 ? A GLU 100 
101 1 Y 1 A SER 101 ? A SER 101 
102 1 Y 1 A THR 102 ? A THR 102 
103 1 Y 1 A GLY 103 ? A GLY 103 
104 1 Y 1 A VAL 104 ? A VAL 104 
105 1 Y 1 A THR 105 ? A THR 105 
106 1 Y 1 A THR 106 ? A THR 106 
107 1 Y 1 A LEU 107 ? A LEU 107 
108 1 Y 1 A ARG 108 ? A ARG 108 
109 1 Y 1 A GLN 109 ? A GLN 109 
110 1 Y 1 A ARG 110 ? A ARG 110 
111 1 Y 1 A ARG 111 ? A ARG 111 
112 1 Y 1 A LYS 112 ? A LYS 112 
113 1 Y 1 A PRO 113 ? A PRO 113 
114 1 Y 1 A VAL 114 ? A VAL 114 
115 1 Y 1 A PHE 115 ? A PHE 115 
116 1 Y 1 A HIS 116 ? A HIS 116 
117 1 Y 1 A LEU 117 ? A LEU 117 
118 1 Y 1 A SER 118 ? A SER 118 
119 1 Y 1 A HIS 119 ? A HIS 119 
120 1 Y 1 A GLU 120 ? A GLU 120 
121 1 Y 1 A GLU 121 ? A GLU 121 
122 1 Y 1 A ARG 122 ? A ARG 122 
123 1 Y 1 A VAL 123 ? A VAL 123 
124 1 Y 1 A GLN 124 ? A GLN 124 
125 1 Y 1 A HIS 125 ? A HIS 125 
126 1 Y 1 A ARG 126 ? A ARG 126 
127 1 Y 1 A ASN 127 ? A ASN 127 
128 1 Y 1 A ILE 128 ? A ILE 128 
129 1 Y 1 A LYS 129 ? A LYS 129 
130 1 Y 1 A ASP 130 ? A ASP 130 
131 1 Y 1 A LEU 131 ? A LEU 131 
132 1 Y 1 A LYS 132 ? A LYS 132 
133 1 Y 1 A LEU 133 ? A LEU 133 
134 1 Y 1 A ALA 134 ? A ALA 134 
135 1 Y 1 A PHE 135 ? A PHE 135 
136 1 Y 1 A SER 136 ? A SER 136 
137 1 Y 1 A GLU 137 ? A GLU 137 
138 1 Y 1 A PHE 138 ? A PHE 138 
139 1 Y 1 A TYR 139 ? A TYR 139 
140 1 Y 1 A LEU 140 ? A LEU 140 
141 1 Y 1 A SER 141 ? A SER 141 
142 1 Y 1 A LEU 142 ? A LEU 142 
143 1 Y 1 A ILE 143 ? A ILE 143 
144 1 Y 1 A LEU 144 ? A LEU 144 
145 1 Y 1 A LEU 145 ? A LEU 145 
146 1 Y 1 A GLN 146 ? A GLN 146 
147 1 Y 1 A ASN 147 ? A ASN 147 
148 1 Y 1 A TYR 148 ? A TYR 148 
149 1 Y 1 A GLN 149 ? A GLN 149 
150 1 Y 1 A ASN 150 ? A ASN 150 
151 1 Y 1 A LEU 151 ? A LEU 151 
152 1 Y 1 A ASN 152 ? A ASN 152 
153 1 Y 1 A PHE 153 ? A PHE 153 
154 1 Y 1 A THR 154 ? A THR 154 
155 1 Y 1 A GLY 155 ? A GLY 155 
156 1 Y 1 A PHE 156 ? A PHE 156 
157 1 Y 1 A ARG 157 ? A ARG 157 
158 1 Y 1 A LYS 158 ? A LYS 158 
159 1 Y 1 A ILE 159 ? A ILE 159 
160 1 Y 1 A LEU 160 ? A LEU 160 
161 1 Y 1 A LYS 161 ? A LYS 161 
162 1 Y 1 A LYS 162 ? A LYS 162 
163 1 Y 1 A HIS 163 ? A HIS 163 
164 1 Y 1 A ASP 164 ? A ASP 164 
165 1 Y 1 A LYS 165 ? A LYS 165 
166 1 Y 1 A ILE 166 ? A ILE 166 
167 1 Y 1 A LEU 167 ? A LEU 167 
168 1 Y 1 A GLU 168 ? A GLU 168 
169 1 Y 1 A THR 169 ? A THR 169 
170 1 Y 1 A SER 170 ? A SER 170 
171 1 Y 1 A ARG 171 ? A ARG 171 
172 1 Y 1 A GLY 172 ? A GLY 172 
173 1 Y 1 A ALA 173 ? A ALA 173 
174 1 Y 1 A ASP 174 ? A ASP 174 
175 1 Y 1 A TRP 175 ? A TRP 175 
176 1 Y 1 A ARG 176 ? A ARG 176 
177 1 Y 1 A VAL 177 ? A VAL 177 
178 1 Y 1 A ALA 178 ? A ALA 178 
179 1 Y 1 A HIS 179 ? A HIS 179 
180 1 Y 1 A VAL 180 ? A VAL 180 
181 1 Y 1 A GLU 181 ? A GLU 181 
182 1 Y 1 A VAL 182 ? A VAL 182 
183 1 Y 1 A ALA 183 ? A ALA 183 
184 1 Y 1 A PRO 184 ? A PRO 184 
185 1 Y 1 A PHE 185 ? A PHE 185 
186 1 Y 1 A TYR 186 ? A TYR 186 
187 1 Y 1 A THR 187 ? A THR 187 
188 1 Y 1 A CYS 188 ? A CYS 188 
189 1 Y 1 A LYS 189 ? A LYS 189 
190 1 Y 1 A LYS 190 ? A LYS 190 
191 1 Y 1 A ILE 191 ? A ILE 191 
192 1 Y 1 A ASN 192 ? A ASN 192 
193 1 Y 1 A GLN 193 ? A GLN 193 
194 1 Y 1 A LEU 194 ? A LEU 194 
195 1 Y 1 A ILE 195 ? A ILE 195 
196 1 Y 1 A SER 196 ? A SER 196 
197 1 Y 1 A GLU 197 ? A GLU 197 
198 1 Y 1 A THR 198 ? A THR 198 
199 1 Y 1 A GLU 199 ? A GLU 199 
200 1 Y 1 A ALA 200 ? A ALA 200 
201 1 Y 1 A VAL 201 ? A VAL 201 
202 1 Y 1 A VAL 202 ? A VAL 202 
203 1 Y 1 A THR 203 ? A THR 203 
204 1 Y 1 A ASN 204 ? A ASN 204 
205 1 Y 1 A GLU 205 ? A GLU 205 
206 1 Y 1 A LEU 206 ? A LEU 206 
207 1 Y 1 A GLU 207 ? A GLU 207 
208 1 Y 1 A ASP 208 ? A ASP 208 
209 1 Y 1 A GLY 209 ? A GLY 209 
210 1 Y 1 A ASP 210 ? A ASP 210 
211 1 Y 1 A ARG 211 ? A ARG 211 
212 1 Y 1 A GLN 212 ? A GLN 212 
213 1 Y 1 A LYS 213 ? A LYS 213 
214 1 Y 1 A ALA 214 ? A ALA 214 
215 1 Y 1 A MET 215 ? A MET 215 
216 1 Y 1 A LYS 216 ? A LYS 216 
217 1 Y 1 A ARG 217 ? A ARG 217 
218 1 Y 1 A LEU 218 ? A LEU 218 
219 1 Y 1 A ARG 219 ? A ARG 219 
220 1 Y 1 A VAL 220 ? A VAL 220 
221 1 Y 1 A PRO 221 ? A PRO 221 
222 1 Y 1 A PRO 222 ? A PRO 222 
223 1 Y 1 A LEU 223 ? A LEU 223 
224 1 Y 1 A GLY 224 ? A GLY 224 
225 1 Y 1 A ALA 225 ? A ALA 225 
226 1 Y 1 A ALA 226 ? A ALA 226 
227 1 Y 1 A GLN 227 ? A GLN 227 
228 1 Y 1 A PRO 228 ? A PRO 228 
229 1 Y 1 A ALA 229 ? A ALA 229 
230 1 Y 1 A PRO 230 ? A PRO 230 
231 1 Y 1 A TRP 423 ? A TRP 423 
232 1 Y 1 A ASP 424 ? A ASP 424 
233 1 Y 1 A GLU 425 ? A GLU 425 
234 1 Y 1 A SER 426 ? A SER 426 
235 1 Y 1 A LYS 427 ? A LYS 427 
236 1 Y 1 A GLY 428 ? A GLY 428 
237 1 Y 1 A LEU 429 ? A LEU 429 
238 1 Y 1 A LEU 430 ? A LEU 430 
239 1 Y 1 A PRO 431 ? A PRO 431 
240 1 Y 1 A ASN 432 ? A ASN 432 
241 1 Y 1 A ASN 433 ? A ASN 433 
242 1 Y 1 A SER 434 ? A SER 434 
243 1 Y 1 A GLU 435 ? A GLU 435 
244 1 Y 1 A GLU 436 ? A GLU 436 
245 1 Y 1 A SER 437 ? A SER 437 
246 1 Y 1 A GLY 438 ? A GLY 438 
247 1 Y 1 A ILE 439 ? A ILE 439 
248 1 Y 1 A CYS 440 ? A CYS 440 
249 1 Y 1 A HIS 441 ? A HIS 441 
250 1 Y 1 A LYS 442 ? A LYS 442 
251 1 Y 1 A VAL 626 ? A VAL 626 
252 1 Y 1 A ARG 627 ? A ARG 627 
253 1 Y 1 A ASP 628 ? A ASP 628 
254 1 Y 1 A ILE 629 ? A ILE 629 
255 1 Y 1 A SER 630 ? A SER 630 
256 1 Y 1 A VAL 631 ? A VAL 631 
257 1 Y 1 A ALA 632 ? A ALA 632 
258 1 Y 1 A PRO 633 ? A PRO 633 
259 1 Y 1 A LEU 634 ? A LEU 634 
260 1 Y 1 A ASN 635 ? A ASN 635 
261 1 Y 1 A ALA 636 ? A ALA 636 
262 1 Y 1 A ASP 637 ? A ASP 637 
263 1 Y 1 A ASP 638 ? A ASP 638 
264 1 Y 1 A GLN 639 ? A GLN 639 
265 1 Y 1 A THR 640 ? A THR 640 
266 1 Y 1 A LEU 641 ? A LEU 641 
267 1 Y 1 A LEU 642 ? A LEU 642 
268 1 Y 1 A GLU 643 ? A GLU 643 
269 1 Y 1 A GLN 644 ? A GLN 644 
270 1 Y 1 A MET 645 ? A MET 645 
271 1 Y 1 A MET 646 ? A MET 646 
272 1 Y 1 A ASP 647 ? A ASP 647 
273 1 Y 1 A GLN 648 ? A GLN 648 
274 1 Y 1 A ASP 649 ? A ASP 649 
275 1 Y 1 A ASP 650 ? A ASP 650 
276 1 Y 1 A GLY 651 ? A GLY 651 
277 1 Y 1 A VAL 652 ? A VAL 652 
278 1 Y 1 A ARG 653 ? A ARG 653 
279 1 Y 1 A ASN 654 ? A ASN 654 
280 1 Y 1 A ARG 655 ? A ARG 655 
281 1 Y 1 A GLN 656 ? A GLN 656 
282 1 Y 1 A LYS 657 ? A LYS 657 
283 1 Y 1 A ASN 658 ? A ASN 658 
284 1 Y 1 A ARG 659 ? A ARG 659 
285 1 Y 1 A SER 660 ? A SER 660 
286 1 Y 1 A TRP 661 ? A TRP 661 
287 1 Y 1 A LYS 662 ? A LYS 662 
288 1 Y 1 A TYR 663 ? A TYR 663 
289 1 Y 1 A ASN 664 ? A ASN 664 
290 1 Y 1 A GLN 665 ? A GLN 665 
291 1 Y 1 A SER 666 ? A SER 666 
292 1 Y 1 A ILE 667 ? A ILE 667 
293 1 Y 1 A SER 668 ? A SER 668 
294 1 Y 1 A LEU 669 ? A LEU 669 
295 1 Y 1 A ARG 670 ? A ARG 670 
296 1 Y 1 A ARG 671 ? A ARG 671 
297 1 Y 1 A PRO 672 ? A PRO 672 
298 1 Y 1 A ARG 673 ? A ARG 673 
299 1 Y 1 A LEU 674 ? A LEU 674 
300 1 Y 1 A ALA 675 ? A ALA 675 
301 1 Y 1 A SER 676 ? A SER 676 
302 1 Y 1 A GLN 677 ? A GLN 677 
303 1 Y 1 A SER 678 ? A SER 678 
304 1 Y 1 A LYS 679 ? A LYS 679 
305 1 Y 1 A ALA 680 ? A ALA 680 
306 1 Y 1 A ARG 681 ? A ARG 681 
307 1 Y 1 A ASP 682 ? A ASP 682 
308 1 Y 1 A THR 683 ? A THR 683 
309 1 Y 1 A LYS 684 ? A LYS 684 
310 1 Y 1 A VAL 685 ? A VAL 685 
311 1 Y 1 A LEU 686 ? A LEU 686 
312 1 Y 1 A ILE 687 ? A ILE 687 
313 1 Y 1 A GLU 688 ? A GLU 688 
314 1 Y 1 A ASP 689 ? A ASP 689 
315 1 Y 1 A THR 690 ? A THR 690 
316 1 Y 1 A ASP 691 ? A ASP 691 
317 1 Y 1 A ASP 692 ? A ASP 692 
318 1 Y 1 A GLU 693 ? A GLU 693 
319 1 Y 1 A ALA 694 ? A ALA 694 
320 1 Y 1 A ASN 695 ? A ASN 695 
321 1 Y 1 A THR 696 ? A THR 696 
322 1 Y 1 A GLU 697 ? A GLU 697 
323 1 Y 1 A ASN 698 ? A ASN 698 
324 1 Y 1 A LEU 699 ? A LEU 699 
325 1 Y 1 A TYR 700 ? A TYR 700 
326 1 Y 1 A PHE 701 ? A PHE 701 
327 1 Y 1 A GLN 702 ? A GLN 702 
328 1 Y 1 A GLY 703 ? A GLY 703 
329 1 Y 1 A HIS 704 ? A HIS 704 
330 1 Y 1 A HIS 705 ? A HIS 705 
331 1 Y 1 A HIS 706 ? A HIS 706 
332 1 Y 1 A HIS 707 ? A HIS 707 
333 1 Y 1 A HIS 708 ? A HIS 708 
334 1 Y 1 A HIS 709 ? A HIS 709 
335 1 Y 1 A HIS 710 ? A HIS 710 
336 1 Y 1 A HIS 711 ? A HIS 711 
337 1 Y 1 A SER 712 ? A SER 712 
338 1 Y 1 A GLY 713 ? A GLY 713 
339 1 Y 1 A ALA 714 ? A ALA 714 
340 1 Y 1 A ALA 715 ? A ALA 715 
341 1 Y 1 A ALA 716 ? A ALA 716 
342 1 Y 1 A TRP 717 ? A TRP 717 
343 1 Y 1 A SER 718 ? A SER 718 
344 1 Y 1 A HIS 719 ? A HIS 719 
345 1 Y 1 A PRO 720 ? A PRO 720 
346 1 Y 1 A GLN 721 ? A GLN 721 
347 1 Y 1 A PHE 722 ? A PHE 722 
348 1 Y 1 A GLU 723 ? A GLU 723 
349 1 Y 1 A LYS 724 ? A LYS 724 
350 1 Y 1 B MET 1   ? B MET 1   
351 1 Y 1 B LYS 2   ? B LYS 2   
352 1 Y 1 B PHE 3   ? B PHE 3   
353 1 Y 1 B ALA 4   ? B ALA 4   
354 1 Y 1 B GLU 5   ? B GLU 5   
355 1 Y 1 B HIS 6   ? B HIS 6   
356 1 Y 1 B LEU 7   ? B LEU 7   
357 1 Y 1 B SER 8   ? B SER 8   
358 1 Y 1 B ALA 9   ? B ALA 9   
359 1 Y 1 B HIS 10  ? B HIS 10  
360 1 Y 1 B ILE 11  ? B ILE 11  
361 1 Y 1 B THR 12  ? B THR 12  
362 1 Y 1 B PRO 13  ? B PRO 13  
363 1 Y 1 B GLU 14  ? B GLU 14  
364 1 Y 1 B TRP 15  ? B TRP 15  
365 1 Y 1 B ARG 16  ? B ARG 16  
366 1 Y 1 B LYS 17  ? B LYS 17  
367 1 Y 1 B GLN 18  ? B GLN 18  
368 1 Y 1 B TYR 19  ? B TYR 19  
369 1 Y 1 B ILE 20  ? B ILE 20  
370 1 Y 1 B GLN 21  ? B GLN 21  
371 1 Y 1 B TYR 22  ? B TYR 22  
372 1 Y 1 B GLU 23  ? B GLU 23  
373 1 Y 1 B ALA 24  ? B ALA 24  
374 1 Y 1 B PHE 25  ? B PHE 25  
375 1 Y 1 B LYS 26  ? B LYS 26  
376 1 Y 1 B ASP 27  ? B ASP 27  
377 1 Y 1 B MET 28  ? B MET 28  
378 1 Y 1 B LEU 29  ? B LEU 29  
379 1 Y 1 B TYR 30  ? B TYR 30  
380 1 Y 1 B SER 31  ? B SER 31  
381 1 Y 1 B ALA 32  ? B ALA 32  
382 1 Y 1 B GLN 33  ? B GLN 33  
383 1 Y 1 B ASP 34  ? B ASP 34  
384 1 Y 1 B GLN 35  ? B GLN 35  
385 1 Y 1 B ALA 36  ? B ALA 36  
386 1 Y 1 B PRO 37  ? B PRO 37  
387 1 Y 1 B SER 38  ? B SER 38  
388 1 Y 1 B VAL 39  ? B VAL 39  
389 1 Y 1 B GLU 40  ? B GLU 40  
390 1 Y 1 B VAL 41  ? B VAL 41  
391 1 Y 1 B THR 42  ? B THR 42  
392 1 Y 1 B ASP 43  ? B ASP 43  
393 1 Y 1 B GLU 44  ? B GLU 44  
394 1 Y 1 B ASP 45  ? B ASP 45  
395 1 Y 1 B THR 46  ? B THR 46  
396 1 Y 1 B VAL 47  ? B VAL 47  
397 1 Y 1 B LYS 48  ? B LYS 48  
398 1 Y 1 B ARG 49  ? B ARG 49  
399 1 Y 1 B TYR 50  ? B TYR 50  
400 1 Y 1 B PHE 51  ? B PHE 51  
401 1 Y 1 B ALA 52  ? B ALA 52  
402 1 Y 1 B LYS 53  ? B LYS 53  
403 1 Y 1 B PHE 54  ? B PHE 54  
404 1 Y 1 B GLU 55  ? B GLU 55  
405 1 Y 1 B GLU 56  ? B GLU 56  
406 1 Y 1 B LYS 57  ? B LYS 57  
407 1 Y 1 B PHE 58  ? B PHE 58  
408 1 Y 1 B PHE 59  ? B PHE 59  
409 1 Y 1 B GLN 60  ? B GLN 60  
410 1 Y 1 B THR 61  ? B THR 61  
411 1 Y 1 B CYS 62  ? B CYS 62  
412 1 Y 1 B GLU 63  ? B GLU 63  
413 1 Y 1 B LYS 64  ? B LYS 64  
414 1 Y 1 B GLU 65  ? B GLU 65  
415 1 Y 1 B LEU 66  ? B LEU 66  
416 1 Y 1 B ALA 67  ? B ALA 67  
417 1 Y 1 B LYS 68  ? B LYS 68  
418 1 Y 1 B ILE 69  ? B ILE 69  
419 1 Y 1 B ASN 70  ? B ASN 70  
420 1 Y 1 B THR 71  ? B THR 71  
421 1 Y 1 B PHE 72  ? B PHE 72  
422 1 Y 1 B TYR 73  ? B TYR 73  
423 1 Y 1 B SER 74  ? B SER 74  
424 1 Y 1 B GLU 75  ? B GLU 75  
425 1 Y 1 B LYS 76  ? B LYS 76  
426 1 Y 1 B LEU 77  ? B LEU 77  
427 1 Y 1 B ALA 78  ? B ALA 78  
428 1 Y 1 B GLU 79  ? B GLU 79  
429 1 Y 1 B ALA 80  ? B ALA 80  
430 1 Y 1 B GLN 81  ? B GLN 81  
431 1 Y 1 B ARG 82  ? B ARG 82  
432 1 Y 1 B ARG 83  ? B ARG 83  
433 1 Y 1 B PHE 84  ? B PHE 84  
434 1 Y 1 B ALA 85  ? B ALA 85  
435 1 Y 1 B THR 86  ? B THR 86  
436 1 Y 1 B LEU 87  ? B LEU 87  
437 1 Y 1 B GLN 88  ? B GLN 88  
438 1 Y 1 B ASN 89  ? B ASN 89  
439 1 Y 1 B GLU 90  ? B GLU 90  
440 1 Y 1 B LEU 91  ? B LEU 91  
441 1 Y 1 B GLN 92  ? B GLN 92  
442 1 Y 1 B SER 93  ? B SER 93  
443 1 Y 1 B SER 94  ? B SER 94  
444 1 Y 1 B LEU 95  ? B LEU 95  
445 1 Y 1 B ASP 96  ? B ASP 96  
446 1 Y 1 B ALA 97  ? B ALA 97  
447 1 Y 1 B GLN 98  ? B GLN 98  
448 1 Y 1 B LYS 99  ? B LYS 99  
449 1 Y 1 B GLU 100 ? B GLU 100 
450 1 Y 1 B SER 101 ? B SER 101 
451 1 Y 1 B THR 102 ? B THR 102 
452 1 Y 1 B GLY 103 ? B GLY 103 
453 1 Y 1 B VAL 104 ? B VAL 104 
454 1 Y 1 B THR 105 ? B THR 105 
455 1 Y 1 B THR 106 ? B THR 106 
456 1 Y 1 B LEU 107 ? B LEU 107 
457 1 Y 1 B ARG 108 ? B ARG 108 
458 1 Y 1 B GLN 109 ? B GLN 109 
459 1 Y 1 B ARG 110 ? B ARG 110 
460 1 Y 1 B ARG 111 ? B ARG 111 
461 1 Y 1 B LYS 112 ? B LYS 112 
462 1 Y 1 B PRO 113 ? B PRO 113 
463 1 Y 1 B VAL 114 ? B VAL 114 
464 1 Y 1 B PHE 115 ? B PHE 115 
465 1 Y 1 B HIS 116 ? B HIS 116 
466 1 Y 1 B LEU 117 ? B LEU 117 
467 1 Y 1 B SER 118 ? B SER 118 
468 1 Y 1 B HIS 119 ? B HIS 119 
469 1 Y 1 B GLU 120 ? B GLU 120 
470 1 Y 1 B GLU 121 ? B GLU 121 
471 1 Y 1 B ARG 122 ? B ARG 122 
472 1 Y 1 B VAL 123 ? B VAL 123 
473 1 Y 1 B GLN 124 ? B GLN 124 
474 1 Y 1 B HIS 125 ? B HIS 125 
475 1 Y 1 B ARG 126 ? B ARG 126 
476 1 Y 1 B ASN 127 ? B ASN 127 
477 1 Y 1 B ILE 128 ? B ILE 128 
478 1 Y 1 B LYS 129 ? B LYS 129 
479 1 Y 1 B ASP 130 ? B ASP 130 
480 1 Y 1 B LEU 131 ? B LEU 131 
481 1 Y 1 B LYS 132 ? B LYS 132 
482 1 Y 1 B LEU 133 ? B LEU 133 
483 1 Y 1 B ALA 134 ? B ALA 134 
484 1 Y 1 B PHE 135 ? B PHE 135 
485 1 Y 1 B SER 136 ? B SER 136 
486 1 Y 1 B GLU 137 ? B GLU 137 
487 1 Y 1 B PHE 138 ? B PHE 138 
488 1 Y 1 B TYR 139 ? B TYR 139 
489 1 Y 1 B LEU 140 ? B LEU 140 
490 1 Y 1 B SER 141 ? B SER 141 
491 1 Y 1 B LEU 142 ? B LEU 142 
492 1 Y 1 B ILE 143 ? B ILE 143 
493 1 Y 1 B LEU 144 ? B LEU 144 
494 1 Y 1 B LEU 145 ? B LEU 145 
495 1 Y 1 B GLN 146 ? B GLN 146 
496 1 Y 1 B ASN 147 ? B ASN 147 
497 1 Y 1 B TYR 148 ? B TYR 148 
498 1 Y 1 B GLN 149 ? B GLN 149 
499 1 Y 1 B ASN 150 ? B ASN 150 
500 1 Y 1 B LEU 151 ? B LEU 151 
501 1 Y 1 B ASN 152 ? B ASN 152 
502 1 Y 1 B PHE 153 ? B PHE 153 
503 1 Y 1 B THR 154 ? B THR 154 
504 1 Y 1 B GLY 155 ? B GLY 155 
505 1 Y 1 B PHE 156 ? B PHE 156 
506 1 Y 1 B ARG 157 ? B ARG 157 
507 1 Y 1 B LYS 158 ? B LYS 158 
508 1 Y 1 B ILE 159 ? B ILE 159 
509 1 Y 1 B LEU 160 ? B LEU 160 
510 1 Y 1 B LYS 161 ? B LYS 161 
511 1 Y 1 B LYS 162 ? B LYS 162 
512 1 Y 1 B HIS 163 ? B HIS 163 
513 1 Y 1 B ASP 164 ? B ASP 164 
514 1 Y 1 B LYS 165 ? B LYS 165 
515 1 Y 1 B ILE 166 ? B ILE 166 
516 1 Y 1 B LEU 167 ? B LEU 167 
517 1 Y 1 B GLU 168 ? B GLU 168 
518 1 Y 1 B THR 169 ? B THR 169 
519 1 Y 1 B SER 170 ? B SER 170 
520 1 Y 1 B ARG 171 ? B ARG 171 
521 1 Y 1 B GLY 172 ? B GLY 172 
522 1 Y 1 B ALA 173 ? B ALA 173 
523 1 Y 1 B ASP 174 ? B ASP 174 
524 1 Y 1 B TRP 175 ? B TRP 175 
525 1 Y 1 B ARG 176 ? B ARG 176 
526 1 Y 1 B VAL 177 ? B VAL 177 
527 1 Y 1 B ALA 178 ? B ALA 178 
528 1 Y 1 B HIS 179 ? B HIS 179 
529 1 Y 1 B VAL 180 ? B VAL 180 
530 1 Y 1 B GLU 181 ? B GLU 181 
531 1 Y 1 B VAL 182 ? B VAL 182 
532 1 Y 1 B ALA 183 ? B ALA 183 
533 1 Y 1 B PRO 184 ? B PRO 184 
534 1 Y 1 B PHE 185 ? B PHE 185 
535 1 Y 1 B TYR 186 ? B TYR 186 
536 1 Y 1 B THR 187 ? B THR 187 
537 1 Y 1 B CYS 188 ? B CYS 188 
538 1 Y 1 B LYS 189 ? B LYS 189 
539 1 Y 1 B LYS 190 ? B LYS 190 
540 1 Y 1 B ILE 191 ? B ILE 191 
541 1 Y 1 B ASN 192 ? B ASN 192 
542 1 Y 1 B GLN 193 ? B GLN 193 
543 1 Y 1 B LEU 194 ? B LEU 194 
544 1 Y 1 B ILE 195 ? B ILE 195 
545 1 Y 1 B SER 196 ? B SER 196 
546 1 Y 1 B GLU 197 ? B GLU 197 
547 1 Y 1 B THR 198 ? B THR 198 
548 1 Y 1 B GLU 199 ? B GLU 199 
549 1 Y 1 B ALA 200 ? B ALA 200 
550 1 Y 1 B VAL 201 ? B VAL 201 
551 1 Y 1 B VAL 202 ? B VAL 202 
552 1 Y 1 B THR 203 ? B THR 203 
553 1 Y 1 B ASN 204 ? B ASN 204 
554 1 Y 1 B GLU 205 ? B GLU 205 
555 1 Y 1 B LEU 206 ? B LEU 206 
556 1 Y 1 B GLU 207 ? B GLU 207 
557 1 Y 1 B ASP 208 ? B ASP 208 
558 1 Y 1 B GLY 209 ? B GLY 209 
559 1 Y 1 B ASP 210 ? B ASP 210 
560 1 Y 1 B ARG 211 ? B ARG 211 
561 1 Y 1 B GLN 212 ? B GLN 212 
562 1 Y 1 B LYS 213 ? B LYS 213 
563 1 Y 1 B ALA 214 ? B ALA 214 
564 1 Y 1 B MET 215 ? B MET 215 
565 1 Y 1 B LYS 216 ? B LYS 216 
566 1 Y 1 B ARG 217 ? B ARG 217 
567 1 Y 1 B LEU 218 ? B LEU 218 
568 1 Y 1 B ARG 219 ? B ARG 219 
569 1 Y 1 B VAL 220 ? B VAL 220 
570 1 Y 1 B PRO 221 ? B PRO 221 
571 1 Y 1 B PRO 222 ? B PRO 222 
572 1 Y 1 B LEU 223 ? B LEU 223 
573 1 Y 1 B GLY 224 ? B GLY 224 
574 1 Y 1 B ALA 225 ? B ALA 225 
575 1 Y 1 B ALA 226 ? B ALA 226 
576 1 Y 1 B GLN 227 ? B GLN 227 
577 1 Y 1 B PRO 228 ? B PRO 228 
578 1 Y 1 B ALA 229 ? B ALA 229 
579 1 Y 1 B PRO 230 ? B PRO 230 
580 1 Y 1 B TRP 423 ? B TRP 423 
581 1 Y 1 B ASP 424 ? B ASP 424 
582 1 Y 1 B GLU 425 ? B GLU 425 
583 1 Y 1 B SER 426 ? B SER 426 
584 1 Y 1 B LYS 427 ? B LYS 427 
585 1 Y 1 B GLY 428 ? B GLY 428 
586 1 Y 1 B LEU 429 ? B LEU 429 
587 1 Y 1 B LEU 430 ? B LEU 430 
588 1 Y 1 B PRO 431 ? B PRO 431 
589 1 Y 1 B ASN 432 ? B ASN 432 
590 1 Y 1 B ASN 433 ? B ASN 433 
591 1 Y 1 B SER 434 ? B SER 434 
592 1 Y 1 B GLU 435 ? B GLU 435 
593 1 Y 1 B GLU 436 ? B GLU 436 
594 1 Y 1 B SER 437 ? B SER 437 
595 1 Y 1 B GLY 438 ? B GLY 438 
596 1 Y 1 B ILE 439 ? B ILE 439 
597 1 Y 1 B CYS 440 ? B CYS 440 
598 1 Y 1 B HIS 441 ? B HIS 441 
599 1 Y 1 B LYS 442 ? B LYS 442 
600 1 Y 1 B VAL 626 ? B VAL 626 
601 1 Y 1 B ARG 627 ? B ARG 627 
602 1 Y 1 B ASP 628 ? B ASP 628 
603 1 Y 1 B ILE 629 ? B ILE 629 
604 1 Y 1 B SER 630 ? B SER 630 
605 1 Y 1 B VAL 631 ? B VAL 631 
606 1 Y 1 B ALA 632 ? B ALA 632 
607 1 Y 1 B PRO 633 ? B PRO 633 
608 1 Y 1 B LEU 634 ? B LEU 634 
609 1 Y 1 B ASN 635 ? B ASN 635 
610 1 Y 1 B ALA 636 ? B ALA 636 
611 1 Y 1 B ASP 637 ? B ASP 637 
612 1 Y 1 B ASP 638 ? B ASP 638 
613 1 Y 1 B GLN 639 ? B GLN 639 
614 1 Y 1 B THR 640 ? B THR 640 
615 1 Y 1 B LEU 641 ? B LEU 641 
616 1 Y 1 B LEU 642 ? B LEU 642 
617 1 Y 1 B GLU 643 ? B GLU 643 
618 1 Y 1 B GLN 644 ? B GLN 644 
619 1 Y 1 B MET 645 ? B MET 645 
620 1 Y 1 B MET 646 ? B MET 646 
621 1 Y 1 B ASP 647 ? B ASP 647 
622 1 Y 1 B GLN 648 ? B GLN 648 
623 1 Y 1 B ASP 649 ? B ASP 649 
624 1 Y 1 B ASP 650 ? B ASP 650 
625 1 Y 1 B GLY 651 ? B GLY 651 
626 1 Y 1 B VAL 652 ? B VAL 652 
627 1 Y 1 B ARG 653 ? B ARG 653 
628 1 Y 1 B ASN 654 ? B ASN 654 
629 1 Y 1 B ARG 655 ? B ARG 655 
630 1 Y 1 B GLN 656 ? B GLN 656 
631 1 Y 1 B LYS 657 ? B LYS 657 
632 1 Y 1 B ASN 658 ? B ASN 658 
633 1 Y 1 B ARG 659 ? B ARG 659 
634 1 Y 1 B SER 660 ? B SER 660 
635 1 Y 1 B TRP 661 ? B TRP 661 
636 1 Y 1 B LYS 662 ? B LYS 662 
637 1 Y 1 B TYR 663 ? B TYR 663 
638 1 Y 1 B ASN 664 ? B ASN 664 
639 1 Y 1 B GLN 665 ? B GLN 665 
640 1 Y 1 B SER 666 ? B SER 666 
641 1 Y 1 B ILE 667 ? B ILE 667 
642 1 Y 1 B SER 668 ? B SER 668 
643 1 Y 1 B LEU 669 ? B LEU 669 
644 1 Y 1 B ARG 670 ? B ARG 670 
645 1 Y 1 B ARG 671 ? B ARG 671 
646 1 Y 1 B PRO 672 ? B PRO 672 
647 1 Y 1 B ARG 673 ? B ARG 673 
648 1 Y 1 B LEU 674 ? B LEU 674 
649 1 Y 1 B ALA 675 ? B ALA 675 
650 1 Y 1 B SER 676 ? B SER 676 
651 1 Y 1 B GLN 677 ? B GLN 677 
652 1 Y 1 B SER 678 ? B SER 678 
653 1 Y 1 B LYS 679 ? B LYS 679 
654 1 Y 1 B ALA 680 ? B ALA 680 
655 1 Y 1 B ARG 681 ? B ARG 681 
656 1 Y 1 B ASP 682 ? B ASP 682 
657 1 Y 1 B THR 683 ? B THR 683 
658 1 Y 1 B LYS 684 ? B LYS 684 
659 1 Y 1 B VAL 685 ? B VAL 685 
660 1 Y 1 B LEU 686 ? B LEU 686 
661 1 Y 1 B ILE 687 ? B ILE 687 
662 1 Y 1 B GLU 688 ? B GLU 688 
663 1 Y 1 B ASP 689 ? B ASP 689 
664 1 Y 1 B THR 690 ? B THR 690 
665 1 Y 1 B ASP 691 ? B ASP 691 
666 1 Y 1 B ASP 692 ? B ASP 692 
667 1 Y 1 B GLU 693 ? B GLU 693 
668 1 Y 1 B ALA 694 ? B ALA 694 
669 1 Y 1 B ASN 695 ? B ASN 695 
670 1 Y 1 B THR 696 ? B THR 696 
671 1 Y 1 B GLU 697 ? B GLU 697 
672 1 Y 1 B ASN 698 ? B ASN 698 
673 1 Y 1 B LEU 699 ? B LEU 699 
674 1 Y 1 B TYR 700 ? B TYR 700 
675 1 Y 1 B PHE 701 ? B PHE 701 
676 1 Y 1 B GLN 702 ? B GLN 702 
677 1 Y 1 B GLY 703 ? B GLY 703 
678 1 Y 1 B HIS 704 ? B HIS 704 
679 1 Y 1 B HIS 705 ? B HIS 705 
680 1 Y 1 B HIS 706 ? B HIS 706 
681 1 Y 1 B HIS 707 ? B HIS 707 
682 1 Y 1 B HIS 708 ? B HIS 708 
683 1 Y 1 B HIS 709 ? B HIS 709 
684 1 Y 1 B HIS 710 ? B HIS 710 
685 1 Y 1 B HIS 711 ? B HIS 711 
686 1 Y 1 B SER 712 ? B SER 712 
687 1 Y 1 B GLY 713 ? B GLY 713 
688 1 Y 1 B ALA 714 ? B ALA 714 
689 1 Y 1 B ALA 715 ? B ALA 715 
690 1 Y 1 B ALA 716 ? B ALA 716 
691 1 Y 1 B TRP 717 ? B TRP 717 
692 1 Y 1 B SER 718 ? B SER 718 
693 1 Y 1 B HIS 719 ? B HIS 719 
694 1 Y 1 B PRO 720 ? B PRO 720 
695 1 Y 1 B GLN 721 ? B GLN 721 
696 1 Y 1 B PHE 722 ? B PHE 722 
697 1 Y 1 B GLU 723 ? B GLU 723 
698 1 Y 1 B LYS 724 ? B LYS 724 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-10 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9CL0 
_em_admin.last_update        2025-06-18 
_em_admin.map_release_date   2025-06-18 
_em_admin.title              'Cryo-EM map of human XPR1 in presence of inorganic phosphate and phytic acid' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.85 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    15 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? 1 ? ? ? 
OTHER                      ? 8  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 9  ? 1 ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           15 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R01GM143380 1 
'National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)'      'United States' R01HL162842 2 
# 
_atom_sites.entry_id                    9CL0 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 231 ? 150.501 145.148 136.448 1.00 8.82  ? 231 ALA A N   1 
ATOM 2    C CA  . ALA A 1 231 ? 149.638 145.856 137.386 1.00 3.93  ? 231 ALA A CA  1 
ATOM 3    C C   . ALA A 1 231 ? 149.794 145.307 138.800 1.00 3.95  ? 231 ALA A C   1 
ATOM 4    O O   . ALA A 1 231 ? 149.730 146.055 139.775 1.00 5.01  ? 231 ALA A O   1 
ATOM 5    C CB  . ALA A 1 231 ? 148.190 145.769 136.942 1.00 3.06  ? 231 ALA A CB  1 
ATOM 6    N N   . TRP A 1 232 ? 149.997 143.991 138.905 1.00 0.66  ? 232 TRP A N   1 
ATOM 7    C CA  . TRP A 1 232 ? 150.177 143.378 140.216 1.00 3.78  ? 232 TRP A CA  1 
ATOM 8    C C   . TRP A 1 232 ? 151.457 143.858 140.888 1.00 3.52  ? 232 TRP A C   1 
ATOM 9    O O   . TRP A 1 232 ? 151.512 143.944 142.119 1.00 2.70  ? 232 TRP A O   1 
ATOM 10   C CB  . TRP A 1 232 ? 150.180 141.854 140.095 1.00 1.90  ? 232 TRP A CB  1 
ATOM 11   C CG  . TRP A 1 232 ? 148.808 141.256 140.017 1.00 4.81  ? 232 TRP A CG  1 
ATOM 12   C CD1 . TRP A 1 232 ? 148.285 140.542 138.979 1.00 5.92  ? 232 TRP A CD1 1 
ATOM 13   C CD2 . TRP A 1 232 ? 147.782 141.318 141.018 1.00 4.07  ? 232 TRP A CD2 1 
ATOM 14   N NE1 . TRP A 1 232 ? 146.999 140.157 139.269 1.00 6.74  ? 232 TRP A NE1 1 
ATOM 15   C CE2 . TRP A 1 232 ? 146.666 140.622 140.514 1.00 6.87  ? 232 TRP A CE2 1 
ATOM 16   C CE3 . TRP A 1 232 ? 147.700 141.896 142.288 1.00 2.80  ? 232 TRP A CE3 1 
ATOM 17   C CZ2 . TRP A 1 232 ? 145.483 140.486 141.236 1.00 6.74  ? 232 TRP A CZ2 1 
ATOM 18   C CZ3 . TRP A 1 232 ? 146.523 141.762 143.004 1.00 3.45  ? 232 TRP A CZ3 1 
ATOM 19   C CH2 . TRP A 1 232 ? 145.431 141.061 142.476 1.00 2.08  ? 232 TRP A CH2 1 
ATOM 20   N N   . THR A 1 233 ? 152.490 144.170 140.102 1.00 3.65  ? 233 THR A N   1 
ATOM 21   C CA  . THR A 1 233 ? 153.724 144.707 140.669 1.00 2.75  ? 233 THR A CA  1 
ATOM 22   C C   . THR A 1 233 ? 153.490 146.076 141.297 1.00 2.58  ? 233 THR A C   1 
ATOM 23   O O   . THR A 1 233 ? 153.940 146.344 142.416 1.00 0.04  ? 233 THR A O   1 
ATOM 24   C CB  . THR A 1 233 ? 154.809 144.786 139.591 1.00 5.83  ? 233 THR A CB  1 
ATOM 25   O OG1 . THR A 1 233 ? 155.023 143.487 139.027 1.00 6.89  ? 233 THR A OG1 1 
ATOM 26   C CG2 . THR A 1 233 ? 156.118 145.297 140.182 1.00 0.99  ? 233 THR A CG2 1 
ATOM 27   N N   . THR A 1 234 ? 152.783 146.960 140.587 1.00 0.00  ? 234 THR A N   1 
ATOM 28   C CA  . THR A 1 234 ? 152.478 148.278 141.135 1.00 0.95  ? 234 THR A CA  1 
ATOM 29   C C   . THR A 1 234 ? 151.605 148.168 142.379 1.00 4.45  ? 234 THR A C   1 
ATOM 30   O O   . THR A 1 234 ? 151.819 148.886 143.366 1.00 3.19  ? 234 THR A O   1 
ATOM 31   C CB  . THR A 1 234 ? 151.792 149.143 140.077 1.00 0.00  ? 234 THR A CB  1 
ATOM 32   O OG1 . THR A 1 234 ? 152.465 148.989 138.822 1.00 3.02  ? 234 THR A OG1 1 
ATOM 33   C CG2 . THR A 1 234 ? 151.817 150.605 140.485 1.00 1.27  ? 234 THR A CG2 1 
ATOM 34   N N   . PHE A 1 235 ? 150.613 147.274 142.349 1.00 0.00  ? 235 PHE A N   1 
ATOM 35   C CA  . PHE A 1 235 ? 149.773 147.066 143.522 1.00 0.87  ? 235 PHE A CA  1 
ATOM 36   C C   . PHE A 1 235 ? 150.591 146.567 144.704 1.00 0.00  ? 235 PHE A C   1 
ATOM 37   O O   . PHE A 1 235 ? 150.395 147.021 145.835 1.00 0.00  ? 235 PHE A O   1 
ATOM 38   C CB  . PHE A 1 235 ? 148.648 146.082 143.205 1.00 0.00  ? 235 PHE A CB  1 
ATOM 39   C CG  . PHE A 1 235 ? 147.860 145.666 144.411 1.00 0.00  ? 235 PHE A CG  1 
ATOM 40   C CD1 . PHE A 1 235 ? 146.896 146.504 144.944 1.00 0.95  ? 235 PHE A CD1 1 
ATOM 41   C CD2 . PHE A 1 235 ? 148.096 144.448 145.024 1.00 0.00  ? 235 PHE A CD2 1 
ATOM 42   C CE1 . PHE A 1 235 ? 146.173 146.130 146.059 1.00 0.00  ? 235 PHE A CE1 1 
ATOM 43   C CE2 . PHE A 1 235 ? 147.377 144.069 146.141 1.00 0.00  ? 235 PHE A CE2 1 
ATOM 44   C CZ  . PHE A 1 235 ? 146.414 144.912 146.658 1.00 0.00  ? 235 PHE A CZ  1 
ATOM 45   N N   . ARG A 1 236 ? 151.502 145.622 144.464 1.00 0.75  ? 236 ARG A N   1 
ATOM 46   C CA  . ARG A 1 236 ? 152.338 145.107 145.542 1.00 1.13  ? 236 ARG A CA  1 
ATOM 47   C C   . ARG A 1 236 ? 153.253 146.193 146.093 1.00 1.52  ? 236 ARG A C   1 
ATOM 48   O O   . ARG A 1 236 ? 153.481 146.265 147.305 1.00 0.00  ? 236 ARG A O   1 
ATOM 49   C CB  . ARG A 1 236 ? 153.150 143.908 145.052 1.00 3.26  ? 236 ARG A CB  1 
ATOM 50   C CG  . ARG A 1 236 ? 152.511 142.565 145.369 1.00 0.63  ? 236 ARG A CG  1 
ATOM 51   C CD  . ARG A 1 236 ? 153.411 141.406 144.983 1.00 1.06  ? 236 ARG A CD  1 
ATOM 52   N NE  . ARG A 1 236 ? 153.915 141.532 143.621 1.00 1.56  ? 236 ARG A NE  1 
ATOM 53   C CZ  . ARG A 1 236 ? 153.613 140.705 142.629 1.00 3.34  ? 236 ARG A CZ  1 
ATOM 54   N NH1 . ARG A 1 236 ? 152.805 139.675 142.810 1.00 4.65  ? 236 ARG A NH1 1 
ATOM 55   N NH2 . ARG A 1 236 ? 154.134 140.920 141.425 1.00 3.76  ? 236 ARG A NH2 1 
ATOM 56   N N   . VAL A 1 237 ? 153.786 147.047 145.216 1.00 0.00  ? 237 VAL A N   1 
ATOM 57   C CA  . VAL A 1 237 ? 154.623 148.157 145.666 1.00 0.00  ? 237 VAL A CA  1 
ATOM 58   C C   . VAL A 1 237 ? 153.826 149.084 146.574 1.00 1.52  ? 237 VAL A C   1 
ATOM 59   O O   . VAL A 1 237 ? 154.280 149.460 147.661 1.00 0.08  ? 237 VAL A O   1 
ATOM 60   C CB  . VAL A 1 237 ? 155.207 148.913 144.458 1.00 1.27  ? 237 VAL A CB  1 
ATOM 61   C CG1 . VAL A 1 237 ? 155.675 150.301 144.869 1.00 0.26  ? 237 VAL A CG1 1 
ATOM 62   C CG2 . VAL A 1 237 ? 156.348 148.125 143.839 1.00 0.00  ? 237 VAL A CG2 1 
ATOM 63   N N   . GLY A 1 238 ? 152.615 149.453 146.146 1.00 1.94  ? 238 GLY A N   1 
ATOM 64   C CA  . GLY A 1 238 ? 151.776 150.305 146.976 1.00 0.00  ? 238 GLY A CA  1 
ATOM 65   C C   . GLY A 1 238 ? 151.414 149.661 148.302 1.00 0.00  ? 238 GLY A C   1 
ATOM 66   O O   . GLY A 1 238 ? 151.427 150.316 149.348 1.00 0.00  ? 238 GLY A O   1 
ATOM 67   N N   . LEU A 1 239 ? 151.088 148.368 148.274 1.00 0.00  ? 239 LEU A N   1 
ATOM 68   C CA  . LEU A 1 239 ? 150.708 147.658 149.490 1.00 0.00  ? 239 LEU A CA  1 
ATOM 69   C C   . LEU A 1 239 ? 151.867 147.601 150.478 1.00 0.36  ? 239 LEU A C   1 
ATOM 70   O O   . LEU A 1 239 ? 151.698 147.880 151.674 1.00 0.00  ? 239 LEU A O   1 
ATOM 71   C CB  . LEU A 1 239 ? 150.231 146.249 149.132 1.00 0.00  ? 239 LEU A CB  1 
ATOM 72   C CG  . LEU A 1 239 ? 149.752 145.332 150.259 1.00 0.66  ? 239 LEU A CG  1 
ATOM 73   C CD1 . LEU A 1 239 ? 148.314 145.642 150.639 1.00 1.58  ? 239 LEU A CD1 1 
ATOM 74   C CD2 . LEU A 1 239 ? 149.899 143.874 149.858 1.00 0.00  ? 239 LEU A CD2 1 
ATOM 75   N N   . PHE A 1 240 ? 153.059 147.245 149.989 1.00 3.40  ? 240 PHE A N   1 
ATOM 76   C CA  . PHE A 1 240 ? 154.229 147.183 150.856 1.00 1.89  ? 240 PHE A CA  1 
ATOM 77   C C   . PHE A 1 240 ? 154.582 148.562 151.394 1.00 0.00  ? 240 PHE A C   1 
ATOM 78   O O   . PHE A 1 240 ? 154.959 148.696 152.560 1.00 0.00  ? 240 PHE A O   1 
ATOM 79   C CB  . PHE A 1 240 ? 155.417 146.569 150.113 1.00 2.70  ? 240 PHE A CB  1 
ATOM 80   C CG  . PHE A 1 240 ? 155.216 145.128 149.726 1.00 1.99  ? 240 PHE A CG  1 
ATOM 81   C CD1 . PHE A 1 240 ? 154.287 144.339 150.387 1.00 1.91  ? 240 PHE A CD1 1 
ATOM 82   C CD2 . PHE A 1 240 ? 155.955 144.564 148.700 1.00 0.00  ? 240 PHE A CD2 1 
ATOM 83   C CE1 . PHE A 1 240 ? 154.099 143.017 150.031 1.00 1.61  ? 240 PHE A CE1 1 
ATOM 84   C CE2 . PHE A 1 240 ? 155.773 143.242 148.339 1.00 0.77  ? 240 PHE A CE2 1 
ATOM 85   C CZ  . PHE A 1 240 ? 154.843 142.467 149.004 1.00 2.88  ? 240 PHE A CZ  1 
ATOM 86   N N   . CYS A 1 241 ? 154.447 149.602 150.566 1.00 0.00  ? 241 CYS A N   1 
ATOM 87   C CA  . CYS A 1 241 ? 154.728 150.955 151.034 1.00 0.88  ? 241 CYS A CA  1 
ATOM 88   C C   . CYS A 1 241 ? 153.764 151.378 152.137 1.00 1.88  ? 241 CYS A C   1 
ATOM 89   O O   . CYS A 1 241 ? 154.183 151.959 153.145 1.00 0.70  ? 241 CYS A O   1 
ATOM 90   C CB  . CYS A 1 241 ? 154.669 151.932 149.860 1.00 0.00  ? 241 CYS A CB  1 
ATOM 91   S SG  . CYS A 1 241 ? 154.754 153.672 150.324 1.00 14.11 ? 241 CYS A SG  1 
ATOM 92   N N   . GLY A 1 242 ? 152.470 151.093 151.970 1.00 2.78  ? 242 GLY A N   1 
ATOM 93   C CA  . GLY A 1 242 ? 151.506 151.453 153.001 1.00 1.18  ? 242 GLY A CA  1 
ATOM 94   C C   . GLY A 1 242 ? 151.741 150.708 154.301 1.00 0.83  ? 242 GLY A C   1 
ATOM 95   O O   . GLY A 1 242 ? 151.726 151.300 155.390 1.00 2.59  ? 242 GLY A O   1 
ATOM 96   N N   . ILE A 1 243 ? 151.980 149.397 154.204 1.00 0.00  ? 243 ILE A N   1 
ATOM 97   C CA  . ILE A 1 243 ? 152.268 148.606 155.397 1.00 0.09  ? 243 ILE A CA  1 
ATOM 98   C C   . ILE A 1 243 ? 153.531 149.114 156.079 1.00 3.48  ? 243 ILE A C   1 
ATOM 99   O O   . ILE A 1 243 ? 153.584 149.235 157.308 1.00 2.26  ? 243 ILE A O   1 
ATOM 100  C CB  . ILE A 1 243 ? 152.375 147.112 155.038 1.00 3.62  ? 243 ILE A CB  1 
ATOM 101  C CG1 . ILE A 1 243 ? 150.997 146.547 154.694 1.00 1.48  ? 243 ILE A CG1 1 
ATOM 102  C CG2 . ILE A 1 243 ? 153.002 146.325 156.178 1.00 0.00  ? 243 ILE A CG2 1 
ATOM 103  C CD1 . ILE A 1 243 ? 151.036 145.147 154.132 1.00 3.60  ? 243 ILE A CD1 1 
ATOM 104  N N   . PHE A 1 244 ? 154.563 149.432 155.291 1.00 2.47  ? 244 PHE A N   1 
ATOM 105  C CA  . PHE A 1 244 ? 155.818 149.929 155.842 1.00 1.06  ? 244 PHE A CA  1 
ATOM 106  C C   . PHE A 1 244 ? 155.627 151.263 156.552 1.00 2.60  ? 244 PHE A C   1 
ATOM 107  O O   . PHE A 1 244 ? 156.193 151.483 157.626 1.00 4.95  ? 244 PHE A O   1 
ATOM 108  C CB  . PHE A 1 244 ? 156.850 150.057 154.721 1.00 3.09  ? 244 PHE A CB  1 
ATOM 109  C CG  . PHE A 1 244 ? 158.239 150.365 155.196 1.00 2.33  ? 244 PHE A CG  1 
ATOM 110  C CD1 . PHE A 1 244 ? 158.871 149.551 156.120 1.00 3.33  ? 244 PHE A CD1 1 
ATOM 111  C CD2 . PHE A 1 244 ? 158.922 151.466 154.706 1.00 6.64  ? 244 PHE A CD2 1 
ATOM 112  C CE1 . PHE A 1 244 ? 160.154 149.834 156.547 1.00 1.16  ? 244 PHE A CE1 1 
ATOM 113  C CE2 . PHE A 1 244 ? 160.204 151.752 155.131 1.00 6.57  ? 244 PHE A CE2 1 
ATOM 114  C CZ  . PHE A 1 244 ? 160.820 150.934 156.054 1.00 1.90  ? 244 PHE A CZ  1 
ATOM 115  N N   . ILE A 1 245 ? 154.843 152.170 155.963 1.00 0.87  ? 245 ILE A N   1 
ATOM 116  C CA  . ILE A 1 245 ? 154.610 153.470 156.589 1.00 0.68  ? 245 ILE A CA  1 
ATOM 117  C C   . ILE A 1 245 ? 153.893 153.295 157.922 1.00 3.93  ? 245 ILE A C   1 
ATOM 118  O O   . ILE A 1 245 ? 154.275 153.892 158.941 1.00 3.14  ? 245 ILE A O   1 
ATOM 119  C CB  . ILE A 1 245 ? 153.819 154.390 155.642 1.00 5.14  ? 245 ILE A CB  1 
ATOM 120  C CG1 . ILE A 1 245 ? 154.709 154.884 154.502 1.00 4.23  ? 245 ILE A CG1 1 
ATOM 121  C CG2 . ILE A 1 245 ? 153.224 155.567 156.404 1.00 3.27  ? 245 ILE A CG2 1 
ATOM 122  C CD1 . ILE A 1 245 ? 153.932 155.398 153.314 1.00 3.34  ? 245 ILE A CD1 1 
ATOM 123  N N   . VAL A 1 246 ? 152.846 152.463 157.938 1.00 1.42  ? 246 VAL A N   1 
ATOM 124  C CA  . VAL A 1 246 ? 152.112 152.246 159.183 1.00 1.92  ? 246 VAL A CA  1 
ATOM 125  C C   . VAL A 1 246 ? 153.014 151.602 160.231 1.00 0.59  ? 246 VAL A C   1 
ATOM 126  O O   . VAL A 1 246 ? 152.991 151.982 161.408 1.00 0.19  ? 246 VAL A O   1 
ATOM 127  C CB  . VAL A 1 246 ? 150.843 151.411 158.929 1.00 3.15  ? 246 VAL A CB  1 
ATOM 128  C CG1 . VAL A 1 246 ? 150.094 151.182 160.235 1.00 2.35  ? 246 VAL A CG1 1 
ATOM 129  C CG2 . VAL A 1 246 ? 149.942 152.109 157.925 1.00 1.66  ? 246 VAL A CG2 1 
ATOM 130  N N   . LEU A 1 247 ? 153.830 150.627 159.823 1.00 2.49  ? 247 LEU A N   1 
ATOM 131  C CA  . LEU A 1 247 ? 154.708 149.955 160.776 1.00 2.28  ? 247 LEU A CA  1 
ATOM 132  C C   . LEU A 1 247 ? 155.802 150.882 161.290 1.00 1.74  ? 247 LEU A C   1 
ATOM 133  O O   . LEU A 1 247 ? 156.219 150.757 162.442 1.00 0.00  ? 247 LEU A O   1 
ATOM 134  C CB  . LEU A 1 247 ? 155.317 148.704 160.142 1.00 2.32  ? 247 LEU A CB  1 
ATOM 135  C CG  . LEU A 1 247 ? 154.360 147.528 159.935 1.00 1.31  ? 247 LEU A CG  1 
ATOM 136  C CD1 . LEU A 1 247 ? 155.118 146.263 159.562 1.00 4.13  ? 247 LEU A CD1 1 
ATOM 137  C CD2 . LEU A 1 247 ? 153.501 147.302 161.171 1.00 0.49  ? 247 LEU A CD2 1 
ATOM 138  N N   . ASN A 1 248 ? 156.277 151.815 160.462 1.00 4.47  ? 248 ASN A N   1 
ATOM 139  C CA  . ASN A 1 248 ? 157.260 152.788 160.929 1.00 1.20  ? 248 ASN A CA  1 
ATOM 140  C C   . ASN A 1 248 ? 156.647 153.748 161.940 1.00 2.27  ? 248 ASN A C   1 
ATOM 141  O O   . ASN A 1 248 ? 157.285 154.095 162.943 1.00 6.40  ? 248 ASN A O   1 
ATOM 142  C CB  . ASN A 1 248 ? 157.842 153.557 159.744 1.00 3.41  ? 248 ASN A CB  1 
ATOM 143  C CG  . ASN A 1 248 ? 158.885 152.759 158.990 1.00 6.12  ? 248 ASN A CG  1 
ATOM 144  O OD1 . ASN A 1 248 ? 159.727 152.097 159.592 1.00 4.73  ? 248 ASN A OD1 1 
ATOM 145  N ND2 . ASN A 1 248 ? 158.836 152.821 157.665 1.00 6.68  ? 248 ASN A ND2 1 
ATOM 146  N N   . ILE A 1 249 ? 155.411 154.190 161.693 1.00 2.96  ? 249 ILE A N   1 
ATOM 147  C CA  . ILE A 1 249 ? 154.716 155.011 162.683 1.00 2.51  ? 249 ILE A CA  1 
ATOM 148  C C   . ILE A 1 249 ? 154.548 154.235 163.986 1.00 3.25  ? 249 ILE A C   1 
ATOM 149  O O   . ILE A 1 249 ? 154.752 154.773 165.085 1.00 6.45  ? 249 ILE A O   1 
ATOM 150  C CB  . ILE A 1 249 ? 153.362 155.490 162.126 1.00 6.45  ? 249 ILE A CB  1 
ATOM 151  C CG1 . ILE A 1 249 ? 153.576 156.412 160.924 1.00 4.07  ? 249 ILE A CG1 1 
ATOM 152  C CG2 . ILE A 1 249 ? 152.545 156.186 163.210 1.00 5.34  ? 249 ILE A CG2 1 
ATOM 153  C CD1 . ILE A 1 249 ? 152.358 157.227 160.550 1.00 4.36  ? 249 ILE A CD1 1 
ATOM 154  N N   . THR A 1 250 ? 154.181 152.955 163.879 1.00 3.53  ? 250 THR A N   1 
ATOM 155  C CA  . THR A 1 250 ? 154.043 152.112 165.062 1.00 1.36  ? 250 THR A CA  1 
ATOM 156  C C   . THR A 1 250 ? 155.366 151.978 165.804 1.00 5.67  ? 250 THR A C   1 
ATOM 157  O O   . THR A 1 250 ? 155.396 152.002 167.038 1.00 7.12  ? 250 THR A O   1 
ATOM 158  C CB  . THR A 1 250 ? 153.516 150.733 164.666 1.00 2.42  ? 250 THR A CB  1 
ATOM 159  O OG1 . THR A 1 250 ? 152.413 150.878 163.764 1.00 6.55  ? 250 THR A OG1 1 
ATOM 160  C CG2 . THR A 1 250 ? 153.064 149.963 165.892 1.00 3.57  ? 250 THR A CG2 1 
ATOM 161  N N   . LEU A 1 251 ? 156.469 151.818 165.069 1.00 5.87  ? 251 LEU A N   1 
ATOM 162  C CA  . LEU A 1 251 ? 157.779 151.708 165.703 1.00 2.79  ? 251 LEU A CA  1 
ATOM 163  C C   . LEU A 1 251 ? 158.151 152.993 166.425 1.00 2.89  ? 251 LEU A C   1 
ATOM 164  O O   . LEU A 1 251 ? 158.710 152.951 167.525 1.00 8.15  ? 251 LEU A O   1 
ATOM 165  C CB  . LEU A 1 251 ? 158.847 151.355 164.669 1.00 7.53  ? 251 LEU A CB  1 
ATOM 166  C CG  . LEU A 1 251 ? 159.016 149.881 164.306 1.00 5.49  ? 251 LEU A CG  1 
ATOM 167  C CD1 . LEU A 1 251 ? 159.785 149.755 163.007 1.00 4.13  ? 251 LEU A CD1 1 
ATOM 168  C CD2 . LEU A 1 251 ? 159.725 149.130 165.422 1.00 2.83  ? 251 LEU A CD2 1 
ATOM 169  N N   . VAL A 1 252 ? 157.864 154.145 165.818 1.00 3.78  ? 252 VAL A N   1 
ATOM 170  C CA  . VAL A 1 252 ? 158.148 155.414 166.483 1.00 4.29  ? 252 VAL A CA  1 
ATOM 171  C C   . VAL A 1 252 ? 157.356 155.520 167.780 1.00 8.12  ? 252 VAL A C   1 
ATOM 172  O O   . VAL A 1 252 ? 157.900 155.867 168.838 1.00 9.52  ? 252 VAL A O   1 
ATOM 173  C CB  . VAL A 1 252 ? 157.853 156.596 165.542 1.00 7.96  ? 252 VAL A CB  1 
ATOM 174  C CG1 . VAL A 1 252 ? 157.830 157.901 166.323 1.00 5.59  ? 252 VAL A CG1 1 
ATOM 175  C CG2 . VAL A 1 252 ? 158.890 156.658 164.433 1.00 7.35  ? 252 VAL A CG2 1 
ATOM 176  N N   . LEU A 1 253 ? 156.059 155.198 167.722 1.00 8.52  ? 253 LEU A N   1 
ATOM 177  C CA  . LEU A 1 253 ? 155.230 155.280 168.923 1.00 8.20  ? 253 LEU A CA  1 
ATOM 178  C C   . LEU A 1 253 ? 155.714 154.314 170.000 1.00 7.26  ? 253 LEU A C   1 
ATOM 179  O O   . LEU A 1 253 ? 155.788 154.675 171.182 1.00 7.36  ? 253 LEU A O   1 
ATOM 180  C CB  . LEU A 1 253 ? 153.768 155.006 168.571 1.00 6.24  ? 253 LEU A CB  1 
ATOM 181  C CG  . LEU A 1 253 ? 153.077 156.044 167.683 1.00 6.84  ? 253 LEU A CG  1 
ATOM 182  C CD1 . LEU A 1 253 ? 151.568 155.901 167.766 1.00 6.52  ? 253 LEU A CD1 1 
ATOM 183  C CD2 . LEU A 1 253 ? 153.500 157.452 168.064 1.00 7.49  ? 253 LEU A CD2 1 
ATOM 184  N N   . ALA A 1 254 ? 156.055 153.084 169.609 1.00 3.29  ? 254 ALA A N   1 
ATOM 185  C CA  . ALA A 1 254 ? 156.525 152.093 170.569 1.00 6.00  ? 254 ALA A CA  1 
ATOM 186  C C   . ALA A 1 254 ? 157.854 152.503 171.189 1.00 8.95  ? 254 ALA A C   1 
ATOM 187  O O   . ALA A 1 254 ? 158.066 152.315 172.391 1.00 10.87 ? 254 ALA A O   1 
ATOM 188  C CB  . ALA A 1 254 ? 156.648 150.728 169.892 1.00 5.99  ? 254 ALA A CB  1 
ATOM 189  N N   . ALA A 1 255 ? 158.763 153.059 170.386 1.00 9.19  ? 255 ALA A N   1 
ATOM 190  C CA  . ALA A 1 255 ? 160.039 153.519 170.920 1.00 6.57  ? 255 ALA A CA  1 
ATOM 191  C C   . ALA A 1 255 ? 159.841 154.671 171.893 1.00 7.96  ? 255 ALA A C   1 
ATOM 192  O O   . ALA A 1 255 ? 160.550 154.768 172.901 1.00 11.69 ? 255 ALA A O   1 
ATOM 193  C CB  . ALA A 1 255 ? 160.969 153.930 169.779 1.00 6.93  ? 255 ALA A CB  1 
ATOM 194  N N   . VAL A 1 256 ? 158.885 155.555 171.608 1.00 10.07 ? 256 VAL A N   1 
ATOM 195  C CA  . VAL A 1 256 ? 158.639 156.675 172.509 1.00 6.06  ? 256 VAL A CA  1 
ATOM 196  C C   . VAL A 1 256 ? 158.009 156.197 173.815 1.00 8.48  ? 256 VAL A C   1 
ATOM 197  O O   . VAL A 1 256 ? 158.353 156.687 174.898 1.00 12.23 ? 256 VAL A O   1 
ATOM 198  C CB  . VAL A 1 256 ? 157.773 157.741 171.812 1.00 11.61 ? 256 VAL A CB  1 
ATOM 199  C CG1 . VAL A 1 256 ? 157.330 158.804 172.803 1.00 6.70  ? 256 VAL A CG1 1 
ATOM 200  C CG2 . VAL A 1 256 ? 158.543 158.379 170.668 1.00 8.68  ? 256 VAL A CG2 1 
ATOM 201  N N   . PHE A 1 257 ? 157.074 155.245 173.713 1.00 10.21 ? 257 PHE A N   1 
ATOM 202  C CA  . PHE A 1 257 ? 156.340 154.786 174.926 1.00 7.96  ? 257 PHE A CA  1 
ATOM 203  C C   . PHE A 1 257 ? 156.924 153.472 175.436 1.00 12.16 ? 257 PHE A C   1 
ATOM 204  O O   . PHE A 1 257 ? 157.675 153.499 176.430 1.00 17.01 ? 257 PHE A O   1 
ATOM 205  C CB  . PHE A 1 257 ? 154.846 154.600 174.639 1.00 8.33  ? 257 PHE A CB  1 
ATOM 206  C CG  . PHE A 1 257 ? 154.194 155.669 173.773 1.00 9.22  ? 257 PHE A CG  1 
ATOM 207  C CD1 . PHE A 1 257 ? 154.461 157.018 173.977 1.00 9.49  ? 257 PHE A CD1 1 
ATOM 208  C CD2 . PHE A 1 257 ? 153.302 155.322 172.765 1.00 9.75  ? 257 PHE A CD2 1 
ATOM 209  C CE1 . PHE A 1 257 ? 153.864 157.986 173.185 1.00 11.19 ? 257 PHE A CE1 1 
ATOM 210  C CE2 . PHE A 1 257 ? 152.708 156.294 171.976 1.00 8.28  ? 257 PHE A CE2 1 
ATOM 211  C CZ  . PHE A 1 257 ? 152.990 157.623 172.188 1.00 7.37  ? 257 PHE A CZ  1 
ATOM 212  N N   . LYS A 1 258 ? 156.606 152.355 174.776 1.00 9.64  ? 258 LYS A N   1 
ATOM 213  C CA  . LYS A 1 258 ? 157.045 151.022 175.273 1.00 6.45  ? 258 LYS A CA  1 
ATOM 214  C C   . LYS A 1 258 ? 158.529 151.056 175.674 1.00 12.10 ? 258 LYS A C   1 
ATOM 215  O O   . LYS A 1 258 ? 158.846 150.585 176.789 1.00 12.34 ? 258 LYS A O   1 
ATOM 216  C CB  . LYS A 1 258 ? 156.808 149.958 174.196 1.00 10.06 ? 258 LYS A CB  1 
ATOM 217  C CG  . LYS A 1 258 ? 155.348 149.672 173.874 1.00 9.77  ? 258 LYS A CG  1 
ATOM 218  C CD  . LYS A 1 258 ? 155.169 148.625 172.781 1.00 10.03 ? 258 LYS A CD  1 
ATOM 219  C CE  . LYS A 1 258 ? 153.731 148.333 172.487 1.00 9.46  ? 258 LYS A CE  1 
ATOM 220  N NZ  . LYS A 1 258 ? 153.580 147.343 171.418 1.00 12.16 ? 258 LYS A NZ  1 
ATOM 221  N N   . LEU A 1 259 ? 159.399 151.589 174.812 1.00 13.04 ? 259 LEU A N   1 
ATOM 222  C CA  . LEU A 1 259 ? 160.860 151.572 175.098 1.00 9.97  ? 259 LEU A CA  1 
ATOM 223  C C   . LEU A 1 259 ? 161.179 152.462 176.309 1.00 11.89 ? 259 LEU A C   1 
ATOM 224  O O   . LEU A 1 259 ? 162.106 152.102 177.068 1.00 12.38 ? 259 LEU A O   1 
ATOM 225  C CB  . LEU A 1 259 ? 161.642 152.020 173.866 1.00 8.18  ? 259 LEU A CB  1 
ATOM 226  C CG  . LEU A 1 259 ? 162.086 150.907 172.913 1.00 7.21  ? 259 LEU A CG  1 
ATOM 227  C CD1 . LEU A 1 259 ? 160.875 150.280 172.246 1.00 8.69  ? 259 LEU A CD1 1 
ATOM 228  C CD2 . LEU A 1 259 ? 163.043 151.470 171.878 1.00 10.13 ? 259 LEU A CD2 1 
ATOM 229  N N   . GLU A 1 260 ? 160.466 153.582 176.467 1.00 9.42  ? 260 GLU A N   1 
ATOM 230  C CA  . GLU A 1 260 ? 160.774 154.535 177.568 1.00 9.93  ? 260 GLU A CA  1 
ATOM 231  C C   . GLU A 1 260 ? 162.253 154.940 177.465 1.00 11.71 ? 260 GLU A C   1 
ATOM 232  O O   . GLU A 1 260 ? 162.698 155.275 176.344 1.00 12.14 ? 260 GLU A O   1 
ATOM 233  C CB  . GLU A 1 260 ? 160.497 153.933 178.947 1.00 7.71  ? 260 GLU A CB  1 
ATOM 234  C CG  . GLU A 1 260 ? 159.039 153.549 179.172 1.00 10.65 ? 260 GLU A CG  1 
ATOM 235  C CD  . GLU A 1 260 ? 158.124 154.724 179.467 1.00 12.85 ? 260 GLU A CD  1 
ATOM 236  O OE1 . GLU A 1 260 ? 156.920 154.629 179.150 1.00 11.17 ? 260 GLU A OE1 1 
ATOM 237  O OE2 . GLU A 1 260 ? 158.615 155.733 180.014 1.00 14.64 ? 260 GLU A OE2 1 
ATOM 238  N N   . THR A 1 261 ? 162.979 154.906 178.586 1.00 13.87 ? 261 THR A N   1 
ATOM 239  C CA  . THR A 1 261 ? 164.419 155.250 178.585 1.00 11.73 ? 261 THR A CA  1 
ATOM 240  C C   . THR A 1 261 ? 165.169 154.207 179.385 1.00 12.01 ? 261 THR A C   1 
ATOM 241  O O   . THR A 1 261 ? 165.559 154.516 180.533 1.00 13.25 ? 261 THR A O   1 
ATOM 242  C CB  . THR A 1 261 ? 164.618 156.651 179.163 1.00 10.36 ? 261 THR A CB  1 
ATOM 243  O OG1 . THR A 1 261 ? 163.668 156.763 180.218 1.00 10.80 ? 261 THR A OG1 1 
ATOM 244  C CG2 . THR A 1 261 ? 164.388 157.745 178.136 1.00 8.19  ? 261 THR A CG2 1 
ATOM 245  N N   . ASP A 1 262 ? 165.364 153.013 178.816 1.00 11.32 ? 262 ASP A N   1 
ATOM 246  C CA  . ASP A 1 262 ? 166.029 151.907 179.561 1.00 12.09 ? 262 ASP A CA  1 
ATOM 247  C C   . ASP A 1 262 ? 166.647 150.909 178.577 1.00 9.04  ? 262 ASP A C   1 
ATOM 248  O O   . ASP A 1 262 ? 166.378 151.057 177.363 1.00 13.33 ? 262 ASP A O   1 
ATOM 249  C CB  . ASP A 1 262 ? 165.058 151.222 180.510 1.00 10.20 ? 262 ASP A CB  1 
ATOM 250  C CG  . ASP A 1 262 ? 164.651 152.044 181.725 1.00 13.70 ? 262 ASP A CG  1 
ATOM 251  O OD1 . ASP A 1 262 ? 165.332 153.053 182.004 1.00 13.83 ? 262 ASP A OD1 1 
ATOM 252  O OD2 . ASP A 1 262 ? 163.660 151.665 182.382 1.00 14.53 ? 262 ASP A OD2 1 
ATOM 253  N N   . ARG A 1 263 ? 167.444 149.954 179.077 1.00 10.19 ? 263 ARG A N   1 
ATOM 254  C CA  . ARG A 1 263 ? 168.079 148.903 178.230 1.00 10.49 ? 263 ARG A CA  1 
ATOM 255  C C   . ARG A 1 263 ? 169.263 149.478 177.432 1.00 14.38 ? 263 ARG A C   1 
ATOM 256  O O   . ARG A 1 263 ? 169.091 150.536 176.787 1.00 12.34 ? 263 ARG A O   1 
ATOM 257  C CB  . ARG A 1 263 ? 167.083 148.228 177.277 1.00 12.58 ? 263 ARG A CB  1 
ATOM 258  C CG  . ARG A 1 263 ? 166.025 147.394 177.986 1.00 9.04  ? 263 ARG A CG  1 
ATOM 259  C CD  . ARG A 1 263 ? 165.086 146.702 177.010 1.00 9.43  ? 263 ARG A CD  1 
ATOM 260  N NE  . ARG A 1 263 ? 164.024 145.956 177.693 1.00 12.51 ? 263 ARG A NE  1 
ATOM 261  C CZ  . ARG A 1 263 ? 163.010 145.358 177.078 1.00 11.59 ? 263 ARG A CZ  1 
ATOM 262  N NH1 . ARG A 1 263 ? 162.526 144.223 177.549 1.00 9.88  ? 263 ARG A NH1 1 
ATOM 263  N NH2 . ARG A 1 263 ? 162.485 145.899 175.994 1.00 14.16 ? 263 ARG A NH2 1 
ATOM 264  N N   . SER A 1 264 ? 170.418 148.805 177.478 1.00 9.92  ? 264 SER A N   1 
ATOM 265  C CA  . SER A 1 264 ? 171.600 149.263 176.701 1.00 7.78  ? 264 SER A CA  1 
ATOM 266  C C   . SER A 1 264 ? 171.074 148.833 175.326 1.00 5.01  ? 264 SER A C   1 
ATOM 267  O O   . SER A 1 264 ? 171.526 147.784 174.823 1.00 10.99 ? 264 SER A O   1 
ATOM 268  C CB  . SER A 1 264 ? 172.941 148.645 176.992 1.00 11.70 ? 264 SER A CB  1 
ATOM 269  O OG  . SER A 1 264 ? 172.838 147.231 177.078 1.00 6.35  ? 264 SER A OG  1 
ATOM 270  N N   . ILE A 1 265 ? 170.149 149.607 174.755 1.00 7.00  ? 265 ILE A N   1 
ATOM 271  C CA  . ILE A 1 265 ? 169.520 149.227 173.454 1.00 6.93  ? 265 ILE A CA  1 
ATOM 272  C C   . ILE A 1 265 ? 170.570 149.364 172.340 1.00 10.19 ? 265 ILE A C   1 
ATOM 273  O O   . ILE A 1 265 ? 170.328 148.840 171.230 1.00 9.23  ? 265 ILE A O   1 
ATOM 274  C CB  . ILE A 1 265 ? 168.190 149.986 173.277 1.00 4.05  ? 265 ILE A CB  1 
ATOM 275  C CG1 . ILE A 1 265 ? 167.142 149.561 174.307 1.00 8.44  ? 265 ILE A CG1 1 
ATOM 276  C CG2 . ILE A 1 265 ? 167.669 149.853 171.845 1.00 5.98  ? 265 ILE A CG2 1 
ATOM 277  C CD1 . ILE A 1 265 ? 165.917 150.456 174.344 1.00 7.99  ? 265 ILE A CD1 1 
ATOM 278  N N   . TRP A 1 266 ? 171.703 150.018 172.619 1.00 8.32  ? 266 TRP A N   1 
ATOM 279  C CA  . TRP A 1 266 ? 172.661 150.234 171.539 1.00 6.96  ? 266 TRP A CA  1 
ATOM 280  C C   . TRP A 1 266 ? 173.126 149.039 170.705 1.00 8.51  ? 266 TRP A C   1 
ATOM 281  O O   . TRP A 1 266 ? 173.295 149.187 169.486 1.00 11.79 ? 266 TRP A O   1 
ATOM 282  C CB  . TRP A 1 266 ? 173.867 150.999 172.089 1.00 6.27  ? 266 TRP A CB  1 
ATOM 283  C CG  . TRP A 1 266 ? 173.634 152.461 172.073 1.00 6.24  ? 266 TRP A CG  1 
ATOM 284  C CD1 . TRP A 1 266 ? 173.419 153.271 173.147 1.00 7.87  ? 266 TRP A CD1 1 
ATOM 285  C CD2 . TRP A 1 266 ? 173.523 153.292 170.915 1.00 7.89  ? 266 TRP A CD2 1 
ATOM 286  N NE1 . TRP A 1 266 ? 173.213 154.562 172.731 1.00 11.73 ? 266 TRP A NE1 1 
ATOM 287  C CE2 . TRP A 1 266 ? 173.269 154.600 171.363 1.00 7.25  ? 266 TRP A CE2 1 
ATOM 288  C CE3 . TRP A 1 266 ? 173.628 153.057 169.539 1.00 9.06  ? 266 TRP A CE3 1 
ATOM 289  C CZ2 . TRP A 1 266 ? 173.116 155.667 170.489 1.00 8.39  ? 266 TRP A CZ2 1 
ATOM 290  C CZ3 . TRP A 1 266 ? 173.476 154.121 168.673 1.00 6.57  ? 266 TRP A CZ3 1 
ATOM 291  C CH2 . TRP A 1 266 ? 173.225 155.409 169.149 1.00 7.95  ? 266 TRP A CH2 1 
ATOM 292  N N   . PRO A 1 267 ? 173.378 147.852 171.303 1.00 3.93  ? 267 PRO A N   1 
ATOM 293  C CA  . PRO A 1 267 ? 173.643 146.672 170.467 1.00 3.26  ? 267 PRO A CA  1 
ATOM 294  C C   . PRO A 1 267 ? 172.537 146.431 169.453 1.00 4.44  ? 267 PRO A C   1 
ATOM 295  O O   . PRO A 1 267 ? 172.804 146.046 168.313 1.00 2.89  ? 267 PRO A O   1 
ATOM 296  C CB  . PRO A 1 267 ? 173.722 145.523 171.481 1.00 4.07  ? 267 PRO A CB  1 
ATOM 297  C CG  . PRO A 1 267 ? 173.881 146.159 172.825 1.00 5.81  ? 267 PRO A CG  1 
ATOM 298  C CD  . PRO A 1 267 ? 173.862 147.646 172.679 1.00 4.50  ? 267 PRO A CD  1 
ATOM 299  N N   . LEU A 1 268 ? 171.289 146.671 169.862 1.00 2.76  ? 268 LEU A N   1 
ATOM 300  C CA  . LEU A 1 268 ? 170.159 146.533 168.949 1.00 2.58  ? 268 LEU A CA  1 
ATOM 301  C C   . LEU A 1 268 ? 170.257 147.520 167.790 1.00 4.12  ? 268 LEU A C   1 
ATOM 302  O O   . LEU A 1 268 ? 169.980 147.167 166.635 1.00 1.69  ? 268 LEU A O   1 
ATOM 303  C CB  . LEU A 1 268 ? 168.856 146.718 169.731 1.00 2.63  ? 268 LEU A CB  1 
ATOM 304  C CG  . LEU A 1 268 ? 167.470 146.601 169.093 1.00 4.93  ? 268 LEU A CG  1 
ATOM 305  C CD1 . LEU A 1 268 ? 166.454 146.321 170.181 1.00 6.97  ? 268 LEU A CD1 1 
ATOM 306  C CD2 . LEU A 1 268 ? 167.091 147.873 168.360 1.00 3.17  ? 268 LEU A CD2 1 
ATOM 307  N N   . ILE A 1 269 ? 170.634 148.768 168.081 1.00 3.81  ? 269 ILE A N   1 
ATOM 308  C CA  . ILE A 1 269 ? 170.783 149.769 167.028 1.00 3.70  ? 269 ILE A CA  1 
ATOM 309  C C   . ILE A 1 269 ? 171.870 149.349 166.048 1.00 3.94  ? 269 ILE A C   1 
ATOM 310  O O   . ILE A 1 269 ? 171.692 149.421 164.827 1.00 2.75  ? 269 ILE A O   1 
ATOM 311  C CB  . ILE A 1 269 ? 171.077 151.153 167.635 1.00 1.95  ? 269 ILE A CB  1 
ATOM 312  C CG1 . ILE A 1 269 ? 169.859 151.675 168.398 1.00 3.56  ? 269 ILE A CG1 1 
ATOM 313  C CG2 . ILE A 1 269 ? 171.491 152.135 166.549 1.00 2.50  ? 269 ILE A CG2 1 
ATOM 314  C CD1 . ILE A 1 269 ? 170.026 153.088 168.916 1.00 3.41  ? 269 ILE A CD1 1 
ATOM 315  N N   . ARG A 1 270 ? 173.012 148.895 166.572 1.00 2.19  ? 270 ARG A N   1 
ATOM 316  C CA  . ARG A 1 270 ? 174.088 148.433 165.701 1.00 4.28  ? 270 ARG A CA  1 
ATOM 317  C C   . ARG A 1 270 ? 173.661 147.228 164.873 1.00 4.21  ? 270 ARG A C   1 
ATOM 318  O O   . ARG A 1 270 ? 174.043 147.112 163.704 1.00 10.29 ? 270 ARG A O   1 
ATOM 319  C CB  . ARG A 1 270 ? 175.330 148.096 166.529 1.00 3.43  ? 270 ARG A CB  1 
ATOM 320  C CG  . ARG A 1 270 ? 175.776 149.212 167.459 1.00 6.06  ? 270 ARG A CG  1 
ATOM 321  C CD  . ARG A 1 270 ? 177.283 149.401 167.436 1.00 7.80  ? 270 ARG A CD  1 
ATOM 322  N NE  . ARG A 1 270 ? 177.851 149.177 166.113 1.00 8.76  ? 270 ARG A NE  1 
ATOM 323  C CZ  . ARG A 1 270 ? 179.141 149.285 165.824 1.00 6.90  ? 270 ARG A CZ  1 
ATOM 324  N NH1 . ARG A 1 270 ? 180.029 149.618 166.746 1.00 0.84  ? 270 ARG A NH1 1 
ATOM 325  N NH2 . ARG A 1 270 ? 179.549 149.053 164.580 1.00 1.44  ? 270 ARG A NH2 1 
ATOM 326  N N   . ILE A 1 271 ? 172.865 146.331 165.456 1.00 0.00  ? 271 ILE A N   1 
ATOM 327  C CA  . ILE A 1 271 ? 172.446 145.120 164.760 1.00 1.53  ? 271 ILE A CA  1 
ATOM 328  C C   . ILE A 1 271 ? 171.468 145.440 163.634 1.00 2.59  ? 271 ILE A C   1 
ATOM 329  O O   . ILE A 1 271 ? 171.553 144.862 162.546 1.00 6.85  ? 271 ILE A O   1 
ATOM 330  C CB  . ILE A 1 271 ? 171.857 144.116 165.770 1.00 3.34  ? 271 ILE A CB  1 
ATOM 331  C CG1 . ILE A 1 271 ? 172.982 143.394 166.515 1.00 3.30  ? 271 ILE A CG1 1 
ATOM 332  C CG2 . ILE A 1 271 ? 170.948 143.115 165.084 1.00 1.35  ? 271 ILE A CG2 1 
ATOM 333  C CD1 . ILE A 1 271 ? 172.500 142.444 167.586 1.00 2.72  ? 271 ILE A CD1 1 
ATOM 334  N N   . TYR A 1 272 ? 170.534 146.363 163.861 1.00 0.00  ? 272 TYR A N   1 
ATOM 335  C CA  . TYR A 1 272 ? 169.519 146.653 162.853 1.00 0.00  ? 272 TYR A CA  1 
ATOM 336  C C   . TYR A 1 272 ? 169.925 147.756 161.877 1.00 0.25  ? 272 TYR A C   1 
ATOM 337  O O   . TYR A 1 272 ? 169.261 147.925 160.841 1.00 1.25  ? 272 TYR A O   1 
ATOM 338  C CB  . TYR A 1 272 ? 168.196 147.017 163.537 1.00 0.56  ? 272 TYR A CB  1 
ATOM 339  C CG  . TYR A 1 272 ? 167.399 145.803 163.960 1.00 0.94  ? 272 TYR A CG  1 
ATOM 340  C CD1 . TYR A 1 272 ? 167.623 145.198 165.190 1.00 0.00  ? 272 TYR A CD1 1 
ATOM 341  C CD2 . TYR A 1 272 ? 166.440 145.248 163.123 1.00 0.63  ? 272 TYR A CD2 1 
ATOM 342  C CE1 . TYR A 1 272 ? 166.908 144.084 165.579 1.00 0.00  ? 272 TYR A CE1 1 
ATOM 343  C CE2 . TYR A 1 272 ? 165.718 144.135 163.503 1.00 0.51  ? 272 TYR A CE2 1 
ATOM 344  C CZ  . TYR A 1 272 ? 165.956 143.556 164.732 1.00 1.86  ? 272 TYR A CZ  1 
ATOM 345  O OH  . TYR A 1 272 ? 165.242 142.448 165.118 1.00 0.00  ? 272 TYR A OH  1 
ATOM 346  N N   . ARG A 1 273 ? 171.012 148.480 162.165 1.00 1.64  ? 273 ARG A N   1 
ATOM 347  C CA  . ARG A 1 273 ? 171.441 149.569 161.295 1.00 0.88  ? 273 ARG A CA  1 
ATOM 348  C C   . ARG A 1 273 ? 171.819 149.066 159.907 1.00 0.54  ? 273 ARG A C   1 
ATOM 349  O O   . ARG A 1 273 ? 171.492 149.706 158.903 1.00 0.00  ? 273 ARG A O   1 
ATOM 350  C CB  . ARG A 1 273 ? 172.612 150.309 161.944 1.00 0.72  ? 273 ARG A CB  1 
ATOM 351  C CG  . ARG A 1 273 ? 173.086 151.537 161.192 1.00 4.69  ? 273 ARG A CG  1 
ATOM 352  C CD  . ARG A 1 273 ? 174.127 152.316 161.990 1.00 1.78  ? 273 ARG A CD  1 
ATOM 353  N NE  . ARG A 1 273 ? 175.201 151.463 162.485 1.00 4.13  ? 273 ARG A NE  1 
ATOM 354  C CZ  . ARG A 1 273 ? 176.086 151.830 163.401 1.00 3.11  ? 273 ARG A CZ  1 
ATOM 355  N NH1 . ARG A 1 273 ? 176.052 153.032 163.953 1.00 0.00  ? 273 ARG A NH1 1 
ATOM 356  N NH2 . ARG A 1 273 ? 177.030 150.970 163.773 1.00 2.35  ? 273 ARG A NH2 1 
ATOM 357  N N   . GLY A 1 274 ? 172.514 147.929 159.830 1.00 2.74  ? 274 GLY A N   1 
ATOM 358  C CA  . GLY A 1 274 ? 172.939 147.418 158.535 1.00 0.00  ? 274 GLY A CA  1 
ATOM 359  C C   . GLY A 1 274 ? 171.779 147.023 157.641 1.00 1.30  ? 274 GLY A C   1 
ATOM 360  O O   . GLY A 1 274 ? 171.774 147.326 156.443 1.00 1.83  ? 274 GLY A O   1 
ATOM 361  N N   . GLY A 1 275 ? 170.783 146.338 158.206 1.00 5.64  ? 275 GLY A N   1 
ATOM 362  C CA  . GLY A 1 275 ? 169.592 146.016 157.438 1.00 0.00  ? 275 GLY A CA  1 
ATOM 363  C C   . GLY A 1 275 ? 168.836 147.254 157.001 1.00 0.00  ? 275 GLY A C   1 
ATOM 364  O O   . GLY A 1 275 ? 168.357 147.334 155.862 1.00 3.26  ? 275 GLY A O   1 
ATOM 365  N N   . PHE A 1 276 ? 168.725 148.245 157.893 1.00 0.00  ? 276 PHE A N   1 
ATOM 366  C CA  . PHE A 1 276 ? 168.078 149.494 157.502 1.00 0.00  ? 276 PHE A CA  1 
ATOM 367  C C   . PHE A 1 276 ? 168.817 150.152 156.340 1.00 0.00  ? 276 PHE A C   1 
ATOM 368  O O   . PHE A 1 276 ? 168.191 150.642 155.392 1.00 0.00  ? 276 PHE A O   1 
ATOM 369  C CB  . PHE A 1 276 ? 167.998 150.445 158.694 1.00 0.00  ? 276 PHE A CB  1 
ATOM 370  C CG  . PHE A 1 276 ? 167.383 151.774 158.363 1.00 2.23  ? 276 PHE A CG  1 
ATOM 371  C CD1 . PHE A 1 276 ? 166.006 151.917 158.301 1.00 0.84  ? 276 PHE A CD1 1 
ATOM 372  C CD2 . PHE A 1 276 ? 168.178 152.879 158.110 1.00 2.93  ? 276 PHE A CD2 1 
ATOM 373  C CE1 . PHE A 1 276 ? 165.435 153.138 157.995 1.00 1.05  ? 276 PHE A CE1 1 
ATOM 374  C CE2 . PHE A 1 276 ? 167.612 154.103 157.804 1.00 0.82  ? 276 PHE A CE2 1 
ATOM 375  C CZ  . PHE A 1 276 ? 166.240 154.233 157.747 1.00 1.96  ? 276 PHE A CZ  1 
ATOM 376  N N   . LEU A 1 277 ? 170.150 150.164 156.399 1.00 0.00  ? 277 LEU A N   1 
ATOM 377  C CA  . LEU A 1 277 ? 170.941 150.779 155.340 1.00 0.00  ? 277 LEU A CA  1 
ATOM 378  C C   . LEU A 1 277 ? 170.793 150.025 154.024 1.00 0.00  ? 277 LEU A C   1 
ATOM 379  O O   . LEU A 1 277 ? 170.751 150.643 152.958 1.00 0.00  ? 277 LEU A O   1 
ATOM 380  C CB  . LEU A 1 277 ? 172.406 150.859 155.762 1.00 0.71  ? 277 LEU A CB  1 
ATOM 381  C CG  . LEU A 1 277 ? 172.663 151.869 156.883 1.00 0.00  ? 277 LEU A CG  1 
ATOM 382  C CD1 . LEU A 1 277 ? 173.953 151.558 157.598 1.00 1.49  ? 277 LEU A CD1 1 
ATOM 383  C CD2 . LEU A 1 277 ? 172.670 153.295 156.353 1.00 0.00  ? 277 LEU A CD2 1 
ATOM 384  N N   . LEU A 1 278 ? 170.710 148.693 154.074 1.00 1.52  ? 278 LEU A N   1 
ATOM 385  C CA  . LEU A 1 278 ? 170.489 147.937 152.844 1.00 1.54  ? 278 LEU A CA  1 
ATOM 386  C C   . LEU A 1 278 ? 169.125 148.253 152.236 1.00 2.07  ? 278 LEU A C   1 
ATOM 387  O O   . LEU A 1 278 ? 168.998 148.386 151.010 1.00 0.00  ? 278 LEU A O   1 
ATOM 388  C CB  . LEU A 1 278 ? 170.626 146.436 153.103 1.00 0.00  ? 278 LEU A CB  1 
ATOM 389  C CG  . LEU A 1 278 ? 170.435 145.575 151.849 1.00 1.33  ? 278 LEU A CG  1 
ATOM 390  C CD1 . LEU A 1 278 ? 171.433 145.962 150.765 1.00 0.74  ? 278 LEU A CD1 1 
ATOM 391  C CD2 . LEU A 1 278 ? 170.547 144.098 152.165 1.00 3.45  ? 278 LEU A CD2 1 
ATOM 392  N N   . ILE A 1 279 ? 168.092 148.378 153.074 1.00 0.00  ? 279 ILE A N   1 
ATOM 393  C CA  . ILE A 1 279 ? 166.771 148.734 152.556 1.00 1.47  ? 279 ILE A CA  1 
ATOM 394  C C   . ILE A 1 279 ? 166.796 150.123 151.922 1.00 2.27  ? 279 ILE A C   1 
ATOM 395  O O   . ILE A 1 279 ? 166.245 150.340 150.831 1.00 2.53  ? 279 ILE A O   1 
ATOM 396  C CB  . ILE A 1 279 ? 165.711 148.627 153.670 1.00 0.00  ? 279 ILE A CB  1 
ATOM 397  C CG1 . ILE A 1 279 ? 165.366 147.159 153.930 1.00 0.00  ? 279 ILE A CG1 1 
ATOM 398  C CG2 . ILE A 1 279 ? 164.455 149.398 153.298 1.00 0.09  ? 279 ILE A CG2 1 
ATOM 399  C CD1 . ILE A 1 279 ? 165.144 146.826 155.388 1.00 0.15  ? 279 ILE A CD1 1 
ATOM 400  N N   . GLU A 1 280 ? 167.440 151.083 152.592 1.00 0.00  ? 280 GLU A N   1 
ATOM 401  C CA  . GLU A 1 280 ? 167.561 152.427 152.033 1.00 0.75  ? 280 GLU A CA  1 
ATOM 402  C C   . GLU A 1 280 ? 168.325 152.409 150.713 1.00 0.00  ? 280 GLU A C   1 
ATOM 403  O O   . GLU A 1 280 ? 167.963 153.118 149.766 1.00 1.14  ? 280 GLU A O   1 
ATOM 404  C CB  . GLU A 1 280 ? 168.246 153.358 153.036 1.00 0.00  ? 280 GLU A CB  1 
ATOM 405  C CG  . GLU A 1 280 ? 168.398 154.795 152.549 1.00 1.44  ? 280 GLU A CG  1 
ATOM 406  C CD  . GLU A 1 280 ? 169.540 155.534 153.227 1.00 0.42  ? 280 GLU A CD  1 
ATOM 407  O OE1 . GLU A 1 280 ? 169.927 155.138 154.344 1.00 2.92  ? 280 GLU A OE1 1 
ATOM 408  O OE2 . GLU A 1 280 ? 170.043 156.520 152.652 1.00 0.54  ? 280 GLU A OE2 1 
ATOM 409  N N   . PHE A 1 281 ? 169.387 151.604 150.637 1.00 0.00  ? 281 PHE A N   1 
ATOM 410  C CA  . PHE A 1 281 ? 170.161 151.496 149.408 1.00 0.00  ? 281 PHE A CA  1 
ATOM 411  C C   . PHE A 1 281 ? 169.313 150.946 148.271 1.00 2.36  ? 281 PHE A C   1 
ATOM 412  O O   . PHE A 1 281 ? 169.378 151.446 147.146 1.00 0.00  ? 281 PHE A O   1 
ATOM 413  C CB  . PHE A 1 281 ? 171.389 150.617 149.643 1.00 0.00  ? 281 PHE A CB  1 
ATOM 414  C CG  . PHE A 1 281 ? 172.233 150.409 148.418 1.00 0.00  ? 281 PHE A CG  1 
ATOM 415  C CD1 . PHE A 1 281 ? 172.920 151.466 147.844 1.00 0.00  ? 281 PHE A CD1 1 
ATOM 416  C CD2 . PHE A 1 281 ? 172.348 149.153 147.847 1.00 0.33  ? 281 PHE A CD2 1 
ATOM 417  C CE1 . PHE A 1 281 ? 173.701 151.277 146.718 1.00 0.00  ? 281 PHE A CE1 1 
ATOM 418  C CE2 . PHE A 1 281 ? 173.130 148.956 146.722 1.00 2.17  ? 281 PHE A CE2 1 
ATOM 419  C CZ  . PHE A 1 281 ? 173.808 150.020 146.157 1.00 0.00  ? 281 PHE A CZ  1 
ATOM 420  N N   . LEU A 1 282 ? 168.507 149.918 148.546 1.00 1.70  ? 282 LEU A N   1 
ATOM 421  C CA  . LEU A 1 282 ? 167.649 149.360 147.504 1.00 4.66  ? 282 LEU A CA  1 
ATOM 422  C C   . LEU A 1 282 ? 166.616 150.378 147.024 1.00 0.09  ? 282 LEU A C   1 
ATOM 423  O O   . LEU A 1 282 ? 166.379 150.514 145.815 1.00 0.09  ? 282 LEU A O   1 
ATOM 424  C CB  . LEU A 1 282 ? 166.969 148.089 148.013 1.00 0.50  ? 282 LEU A CB  1 
ATOM 425  C CG  . LEU A 1 282 ? 167.897 146.880 148.147 1.00 0.50  ? 282 LEU A CG  1 
ATOM 426  C CD1 . LEU A 1 282 ? 167.232 145.759 148.928 1.00 0.00  ? 282 LEU A CD1 1 
ATOM 427  C CD2 . LEU A 1 282 ? 168.351 146.394 146.780 1.00 0.06  ? 282 LEU A CD2 1 
ATOM 428  N N   . PHE A 1 283 ? 166.007 151.118 147.953 1.00 1.57  ? 283 PHE A N   1 
ATOM 429  C CA  . PHE A 1 283 ? 165.023 152.130 147.569 1.00 3.96  ? 283 PHE A CA  1 
ATOM 430  C C   . PHE A 1 283 ? 165.660 153.233 146.719 1.00 0.00  ? 283 PHE A C   1 
ATOM 431  O O   . PHE A 1 283 ? 165.126 153.626 145.666 1.00 0.00  ? 283 PHE A O   1 
ATOM 432  C CB  . PHE A 1 283 ? 164.374 152.704 148.830 1.00 0.05  ? 283 PHE A CB  1 
ATOM 433  C CG  . PHE A 1 283 ? 163.561 153.939 148.594 1.00 3.44  ? 283 PHE A CG  1 
ATOM 434  C CD1 . PHE A 1 283 ? 162.368 153.879 147.893 1.00 3.75  ? 283 PHE A CD1 1 
ATOM 435  C CD2 . PHE A 1 283 ? 163.978 155.162 149.094 1.00 0.18  ? 283 PHE A CD2 1 
ATOM 436  C CE1 . PHE A 1 283 ? 161.615 155.017 147.683 1.00 4.02  ? 283 PHE A CE1 1 
ATOM 437  C CE2 . PHE A 1 283 ? 163.227 156.304 148.888 1.00 2.13  ? 283 PHE A CE2 1 
ATOM 438  C CZ  . PHE A 1 283 ? 162.044 156.231 148.183 1.00 2.90  ? 283 PHE A CZ  1 
ATOM 439  N N   . LEU A 1 284 ? 166.818 153.735 147.155 1.00 1.76  ? 284 LEU A N   1 
ATOM 440  C CA  . LEU A 1 284 ? 167.499 154.775 146.395 1.00 2.67  ? 284 LEU A CA  1 
ATOM 441  C C   . LEU A 1 284 ? 168.002 154.251 145.056 1.00 2.78  ? 284 LEU A C   1 
ATOM 442  O O   . LEU A 1 284 ? 168.070 155.010 144.088 1.00 0.00  ? 284 LEU A O   1 
ATOM 443  C CB  . LEU A 1 284 ? 168.645 155.366 147.219 1.00 0.00  ? 284 LEU A CB  1 
ATOM 444  C CG  . LEU A 1 284 ? 168.212 156.228 148.410 1.00 0.00  ? 284 LEU A CG  1 
ATOM 445  C CD1 . LEU A 1 284 ? 169.407 156.664 149.248 1.00 0.00  ? 284 LEU A CD1 1 
ATOM 446  C CD2 . LEU A 1 284 ? 167.406 157.437 147.950 1.00 0.00  ? 284 LEU A CD2 1 
ATOM 447  N N   . LEU A 1 285 ? 168.334 152.961 144.970 1.00 0.00  ? 285 LEU A N   1 
ATOM 448  C CA  . LEU A 1 285 ? 168.724 152.379 143.692 1.00 0.00  ? 285 LEU A CA  1 
ATOM 449  C C   . LEU A 1 285 ? 167.537 152.300 142.743 1.00 5.82  ? 285 LEU A C   1 
ATOM 450  O O   . LEU A 1 285 ? 167.692 152.464 141.528 1.00 0.00  ? 285 LEU A O   1 
ATOM 451  C CB  . LEU A 1 285 ? 169.333 150.995 143.908 1.00 0.00  ? 285 LEU A CB  1 
ATOM 452  C CG  . LEU A 1 285 ? 170.136 150.424 142.740 1.00 3.54  ? 285 LEU A CG  1 
ATOM 453  C CD1 . LEU A 1 285 ? 171.278 151.360 142.368 1.00 3.50  ? 285 LEU A CD1 1 
ATOM 454  C CD2 . LEU A 1 285 ? 170.660 149.035 143.075 1.00 3.51  ? 285 LEU A CD2 1 
ATOM 455  N N   . GLY A 1 286 ? 166.344 152.040 143.280 1.00 3.48  ? 286 GLY A N   1 
ATOM 456  C CA  . GLY A 1 286 ? 165.148 152.134 142.458 1.00 2.94  ? 286 GLY A CA  1 
ATOM 457  C C   . GLY A 1 286 ? 164.951 153.530 141.896 1.00 4.79  ? 286 GLY A C   1 
ATOM 458  O O   . GLY A 1 286 ? 164.659 153.706 140.706 1.00 0.28  ? 286 GLY A O   1 
ATOM 459  N N   . ILE A 1 287 ? 165.131 154.544 142.744 1.00 0.00  ? 287 ILE A N   1 
ATOM 460  C CA  . ILE A 1 287 ? 165.040 155.924 142.259 1.00 0.00  ? 287 ILE A CA  1 
ATOM 461  C C   . ILE A 1 287 ? 166.127 156.204 141.220 1.00 6.93  ? 287 ILE A C   1 
ATOM 462  O O   . ILE A 1 287 ? 165.892 156.902 140.224 1.00 0.00  ? 287 ILE A O   1 
ATOM 463  C CB  . ILE A 1 287 ? 165.102 156.917 143.435 1.00 0.00  ? 287 ILE A CB  1 
ATOM 464  C CG1 . ILE A 1 287 ? 163.943 156.673 144.404 1.00 0.31  ? 287 ILE A CG1 1 
ATOM 465  C CG2 . ILE A 1 287 ? 165.071 158.354 142.929 1.00 0.00  ? 287 ILE A CG2 1 
ATOM 466  C CD1 . ILE A 1 287 ? 163.838 157.707 145.498 1.00 0.61  ? 287 ILE A CD1 1 
ATOM 467  N N   . ASN A 1 288 ? 167.328 155.657 141.434 1.00 7.16  ? 288 ASN A N   1 
ATOM 468  C CA  . ASN A 1 288 ? 168.427 155.816 140.482 1.00 2.88  ? 288 ASN A CA  1 
ATOM 469  C C   . ASN A 1 288 ? 168.064 155.233 139.124 1.00 0.97  ? 288 ASN A C   1 
ATOM 470  O O   . ASN A 1 288 ? 168.322 155.844 138.082 1.00 0.00  ? 288 ASN A O   1 
ATOM 471  C CB  . ASN A 1 288 ? 169.685 155.126 141.015 1.00 0.00  ? 288 ASN A CB  1 
ATOM 472  C CG  . ASN A 1 288 ? 170.560 156.040 141.845 1.00 2.11  ? 288 ASN A CG  1 
ATOM 473  O OD1 . ASN A 1 288 ? 171.120 155.617 142.854 1.00 0.84  ? 288 ASN A OD1 1 
ATOM 474  N ND2 . ASN A 1 288 ? 170.690 157.290 141.424 1.00 0.00  ? 288 ASN A ND2 1 
ATOM 475  N N   . THR A 1 289 ? 167.486 154.031 139.121 1.00 3.19  ? 289 THR A N   1 
ATOM 476  C CA  . THR A 1 289 ? 167.109 153.379 137.872 1.00 1.11  ? 289 THR A CA  1 
ATOM 477  C C   . THR A 1 289 ? 166.023 154.166 137.153 1.00 1.71  ? 289 THR A C   1 
ATOM 478  O O   . THR A 1 289 ? 166.071 154.333 135.926 1.00 0.00  ? 289 THR A O   1 
ATOM 479  C CB  . THR A 1 289 ? 166.648 151.946 138.151 1.00 2.11  ? 289 THR A CB  1 
ATOM 480  O OG1 . THR A 1 289 ? 167.740 151.190 138.686 1.00 4.44  ? 289 THR A OG1 1 
ATOM 481  C CG2 . THR A 1 289 ? 166.155 151.277 136.880 1.00 1.66  ? 289 THR A CG2 1 
ATOM 482  N N   . TYR A 1 290 ? 165.041 154.674 137.905 1.00 1.07  ? 290 TYR A N   1 
ATOM 483  C CA  . TYR A 1 290 ? 164.012 155.505 137.290 1.00 0.01  ? 290 TYR A CA  1 
ATOM 484  C C   . TYR A 1 290 ? 164.615 156.756 136.661 1.00 0.63  ? 290 TYR A C   1 
ATOM 485  O O   . TYR A 1 290 ? 164.250 157.135 135.542 1.00 0.00  ? 290 TYR A O   1 
ATOM 486  C CB  . TYR A 1 290 ? 162.948 155.881 138.321 1.00 1.34  ? 290 TYR A CB  1 
ATOM 487  C CG  . TYR A 1 290 ? 162.022 156.981 137.858 1.00 0.35  ? 290 TYR A CG  1 
ATOM 488  C CD1 . TYR A 1 290 ? 160.940 156.702 137.035 1.00 2.52  ? 290 TYR A CD1 1 
ATOM 489  C CD2 . TYR A 1 290 ? 162.232 158.300 138.238 1.00 2.26  ? 290 TYR A CD2 1 
ATOM 490  C CE1 . TYR A 1 290 ? 160.094 157.700 136.605 1.00 4.85  ? 290 TYR A CE1 1 
ATOM 491  C CE2 . TYR A 1 290 ? 161.391 159.308 137.811 1.00 2.47  ? 290 TYR A CE2 1 
ATOM 492  C CZ  . TYR A 1 290 ? 160.322 159.001 136.996 1.00 6.10  ? 290 TYR A CZ  1 
ATOM 493  O OH  . TYR A 1 290 ? 159.479 159.999 136.568 1.00 11.57 ? 290 TYR A OH  1 
ATOM 494  N N   . GLY A 1 291 ? 165.542 157.410 137.366 1.00 2.68  ? 291 GLY A N   1 
ATOM 495  C CA  . GLY A 1 291 ? 166.176 158.598 136.817 1.00 0.00  ? 291 GLY A CA  1 
ATOM 496  C C   . GLY A 1 291 ? 167.015 158.304 135.587 1.00 2.26  ? 291 GLY A C   1 
ATOM 497  O O   . GLY A 1 291 ? 167.006 159.074 134.622 1.00 1.07  ? 291 GLY A O   1 
ATOM 498  N N   . TRP A 1 292 ? 167.751 157.189 135.607 1.00 0.32  ? 292 TRP A N   1 
ATOM 499  C CA  . TRP A 1 292 ? 168.528 156.784 134.440 1.00 0.00  ? 292 TRP A CA  1 
ATOM 500  C C   . TRP A 1 292 ? 167.625 156.575 133.236 1.00 1.65  ? 292 TRP A C   1 
ATOM 501  O O   . TRP A 1 292 ? 167.915 157.057 132.135 1.00 1.56  ? 292 TRP A O   1 
ATOM 502  C CB  . TRP A 1 292 ? 169.302 155.497 134.731 1.00 0.00  ? 292 TRP A CB  1 
ATOM 503  C CG  . TRP A 1 292 ? 170.399 155.618 135.736 1.00 0.87  ? 292 TRP A CG  1 
ATOM 504  C CD1 . TRP A 1 292 ? 171.089 156.743 136.076 1.00 3.48  ? 292 TRP A CD1 1 
ATOM 505  C CD2 . TRP A 1 292 ? 170.939 154.560 136.533 1.00 0.37  ? 292 TRP A CD2 1 
ATOM 506  N NE1 . TRP A 1 292 ? 172.022 156.451 137.040 1.00 0.00  ? 292 TRP A NE1 1 
ATOM 507  C CE2 . TRP A 1 292 ? 171.950 155.117 137.338 1.00 1.21  ? 292 TRP A CE2 1 
ATOM 508  C CE3 . TRP A 1 292 ? 170.661 153.194 136.646 1.00 0.00  ? 292 TRP A CE3 1 
ATOM 509  C CZ2 . TRP A 1 292 ? 172.686 154.355 138.244 1.00 2.98  ? 292 TRP A CZ2 1 
ATOM 510  C CZ3 . TRP A 1 292 ? 171.393 152.440 137.545 1.00 0.00  ? 292 TRP A CZ3 1 
ATOM 511  C CH2 . TRP A 1 292 ? 172.395 153.022 138.330 1.00 0.00  ? 292 TRP A CH2 1 
ATOM 512  N N   . ARG A 1 293 ? 166.521 155.847 133.428 1.00 5.21  ? 293 ARG A N   1 
ATOM 513  C CA  . ARG A 1 293 ? 165.619 155.571 132.316 1.00 3.12  ? 293 ARG A CA  1 
ATOM 514  C C   . ARG A 1 293 ? 164.970 156.849 131.796 1.00 1.51  ? 293 ARG A C   1 
ATOM 515  O O   . ARG A 1 293 ? 164.856 157.045 130.582 1.00 3.10  ? 293 ARG A O   1 
ATOM 516  C CB  . ARG A 1 293 ? 164.559 154.555 132.741 1.00 4.45  ? 293 ARG A CB  1 
ATOM 517  C CG  . ARG A 1 293 ? 163.933 153.796 131.584 1.00 5.83  ? 293 ARG A CG  1 
ATOM 518  C CD  . ARG A 1 293 ? 163.679 152.342 131.946 1.00 9.30  ? 293 ARG A CD  1 
ATOM 519  N NE  . ARG A 1 293 ? 164.666 151.453 131.345 1.00 5.57  ? 293 ARG A NE  1 
ATOM 520  C CZ  . ARG A 1 293 ? 165.135 150.353 131.919 1.00 7.85  ? 293 ARG A CZ  1 
ATOM 521  N NH1 . ARG A 1 293 ? 164.731 149.973 133.120 1.00 5.03  ? 293 ARG A NH1 1 
ATOM 522  N NH2 . ARG A 1 293 ? 166.032 149.617 131.271 1.00 11.41 ? 293 ARG A NH2 1 
ATOM 523  N N   . GLN A 1 294 ? 164.542 157.733 132.700 1.00 2.98  ? 294 GLN A N   1 
ATOM 524  C CA  . GLN A 1 294 ? 163.898 158.972 132.272 1.00 2.94  ? 294 GLN A CA  1 
ATOM 525  C C   . GLN A 1 294 ? 164.866 159.876 131.519 1.00 2.51  ? 294 GLN A C   1 
ATOM 526  O O   . GLN A 1 294 ? 164.492 160.491 130.514 1.00 5.81  ? 294 GLN A O   1 
ATOM 527  C CB  . GLN A 1 294 ? 163.309 159.700 133.477 1.00 0.00  ? 294 GLN A CB  1 
ATOM 528  C CG  . GLN A 1 294 ? 162.000 159.114 133.967 1.00 4.40  ? 294 GLN A CG  1 
ATOM 529  C CD  . GLN A 1 294 ? 160.990 158.929 132.851 1.00 4.63  ? 294 GLN A CD  1 
ATOM 530  O OE1 . GLN A 1 294 ? 160.576 157.809 132.552 1.00 12.71 ? 294 GLN A OE1 1 
ATOM 531  N NE2 . GLN A 1 294 ? 160.587 160.031 132.229 1.00 4.04  ? 294 GLN A NE2 1 
ATOM 532  N N   . ALA A 1 295 ? 166.112 159.973 131.985 1.00 5.82  ? 295 ALA A N   1 
ATOM 533  C CA  . ALA A 1 295 ? 167.082 160.843 131.332 1.00 0.27  ? 295 ALA A CA  1 
ATOM 534  C C   . ALA A 1 295 ? 167.597 160.279 130.015 1.00 6.79  ? 295 ALA A C   1 
ATOM 535  O O   . ALA A 1 295 ? 168.063 161.047 129.169 1.00 14.13 ? 295 ALA A O   1 
ATOM 536  C CB  . ALA A 1 295 ? 168.263 161.114 132.265 1.00 0.07  ? 295 ALA A CB  1 
ATOM 537  N N   . GLY A 1 296 ? 167.516 158.970 129.814 1.00 5.63  ? 296 GLY A N   1 
ATOM 538  C CA  . GLY A 1 296 ? 168.067 158.350 128.632 1.00 0.00  ? 296 GLY A CA  1 
ATOM 539  C C   . GLY A 1 296 ? 169.435 157.732 128.804 1.00 3.13  ? 296 GLY A C   1 
ATOM 540  O O   . GLY A 1 296 ? 170.045 157.339 127.803 1.00 7.54  ? 296 GLY A O   1 
ATOM 541  N N   . VAL A 1 297 ? 169.940 157.639 130.034 1.00 0.00  ? 297 VAL A N   1 
ATOM 542  C CA  . VAL A 1 297 ? 171.200 156.949 130.279 1.00 0.88  ? 297 VAL A CA  1 
ATOM 543  C C   . VAL A 1 297 ? 171.000 155.456 130.059 1.00 0.91  ? 297 VAL A C   1 
ATOM 544  O O   . VAL A 1 297 ? 170.068 154.851 130.605 1.00 4.94  ? 297 VAL A O   1 
ATOM 545  C CB  . VAL A 1 297 ? 171.710 157.247 131.697 1.00 3.74  ? 297 VAL A CB  1 
ATOM 546  C CG1 . VAL A 1 297 ? 172.909 156.370 132.033 1.00 1.28  ? 297 VAL A CG1 1 
ATOM 547  C CG2 . VAL A 1 297 ? 172.067 158.717 131.832 1.00 0.74  ? 297 VAL A CG2 1 
ATOM 548  N N   . ASN A 1 298 ? 171.874 154.854 129.254 1.00 0.00  ? 298 ASN A N   1 
ATOM 549  C CA  . ASN A 1 298 ? 171.734 153.453 128.865 1.00 0.16  ? 298 ASN A CA  1 
ATOM 550  C C   . ASN A 1 298 ? 172.513 152.584 129.848 1.00 1.70  ? 298 ASN A C   1 
ATOM 551  O O   . ASN A 1 298 ? 173.586 152.060 129.552 1.00 3.51  ? 298 ASN A O   1 
ATOM 552  C CB  . ASN A 1 298 ? 172.199 153.251 127.428 1.00 3.35  ? 298 ASN A CB  1 
ATOM 553  C CG  . ASN A 1 298 ? 171.744 151.929 126.853 1.00 2.08  ? 298 ASN A CG  1 
ATOM 554  O OD1 . ASN A 1 298 ? 170.825 151.301 127.372 1.00 4.39  ? 298 ASN A OD1 1 
ATOM 555  N ND2 . ASN A 1 298 ? 172.360 151.518 125.755 1.00 5.70  ? 298 ASN A ND2 1 
ATOM 556  N N   . HIS A 1 299 ? 171.940 152.425 131.042 1.00 0.00  ? 299 HIS A N   1 
ATOM 557  C CA  . HIS A 1 299 ? 172.570 151.620 132.080 1.00 0.54  ? 299 HIS A CA  1 
ATOM 558  C C   . HIS A 1 299 ? 172.540 150.130 131.762 1.00 0.70  ? 299 HIS A C   1 
ATOM 559  O O   . HIS A 1 299 ? 173.411 149.394 132.234 1.00 0.53  ? 299 HIS A O   1 
ATOM 560  C CB  . HIS A 1 299 ? 171.893 151.885 133.426 1.00 0.13  ? 299 HIS A CB  1 
ATOM 561  C CG  . HIS A 1 299 ? 170.488 151.378 133.502 1.00 0.59  ? 299 HIS A CG  1 
ATOM 562  N ND1 . HIS A 1 299 ? 170.170 150.140 134.015 1.00 1.55  ? 299 HIS A ND1 1 
ATOM 563  C CD2 . HIS A 1 299 ? 169.316 151.938 133.120 1.00 1.20  ? 299 HIS A CD2 1 
ATOM 564  C CE1 . HIS A 1 299 ? 168.863 149.961 133.952 1.00 2.34  ? 299 HIS A CE1 1 
ATOM 565  N NE2 . HIS A 1 299 ? 168.322 151.038 133.412 1.00 3.16  ? 299 HIS A NE2 1 
ATOM 566  N N   . VAL A 1 300 ? 171.562 149.672 130.976 1.00 3.60  ? 300 VAL A N   1 
ATOM 567  C CA  . VAL A 1 300 ? 171.504 148.260 130.605 1.00 1.21  ? 300 VAL A CA  1 
ATOM 568  C C   . VAL A 1 300 ? 172.730 147.875 129.787 1.00 2.13  ? 300 VAL A C   1 
ATOM 569  O O   . VAL A 1 300 ? 173.299 146.791 129.962 1.00 5.63  ? 300 VAL A O   1 
ATOM 570  C CB  . VAL A 1 300 ? 170.194 147.958 129.852 1.00 3.00  ? 300 VAL A CB  1 
ATOM 571  C CG1 . VAL A 1 300 ? 170.230 146.567 129.237 1.00 2.28  ? 300 VAL A CG1 1 
ATOM 572  C CG2 . VAL A 1 300 ? 169.004 148.096 130.788 1.00 1.10  ? 300 VAL A CG2 1 
ATOM 573  N N   . LEU A 1 301 ? 173.161 148.759 128.886 1.00 1.79  ? 301 LEU A N   1 
ATOM 574  C CA  . LEU A 1 301 ? 174.365 148.490 128.106 1.00 5.41  ? 301 LEU A CA  1 
ATOM 575  C C   . LEU A 1 301 ? 175.624 148.656 128.950 1.00 3.59  ? 301 LEU A C   1 
ATOM 576  O O   . LEU A 1 301 ? 176.562 147.860 128.837 1.00 5.81  ? 301 LEU A O   1 
ATOM 577  C CB  . LEU A 1 301 ? 174.410 149.407 126.885 1.00 0.53  ? 301 LEU A CB  1 
ATOM 578  C CG  . LEU A 1 301 ? 175.775 149.758 126.292 1.00 1.93  ? 301 LEU A CG  1 
ATOM 579  C CD1 . LEU A 1 301 ? 176.301 148.620 125.430 1.00 3.54  ? 301 LEU A CD1 1 
ATOM 580  C CD2 . LEU A 1 301 ? 175.692 151.048 125.492 1.00 2.44  ? 301 LEU A CD2 1 
ATOM 581  N N   . ILE A 1 302 ? 175.663 149.688 129.798 1.00 0.61  ? 302 ILE A N   1 
ATOM 582  C CA  . ILE A 1 302 ? 176.854 149.954 130.602 1.00 0.67  ? 302 ILE A CA  1 
ATOM 583  C C   . ILE A 1 302 ? 177.104 148.819 131.586 1.00 1.80  ? 302 ILE A C   1 
ATOM 584  O O   . ILE A 1 302 ? 178.241 148.364 131.755 1.00 6.49  ? 302 ILE A O   1 
ATOM 585  C CB  . ILE A 1 302 ? 176.719 151.314 131.314 1.00 6.12  ? 302 ILE A CB  1 
ATOM 586  C CG1 . ILE A 1 302 ? 176.668 152.441 130.280 1.00 0.00  ? 302 ILE A CG1 1 
ATOM 587  C CG2 . ILE A 1 302 ? 177.864 151.526 132.301 1.00 0.00  ? 302 ILE A CG2 1 
ATOM 588  C CD1 . ILE A 1 302 ? 176.521 153.812 130.871 1.00 0.34  ? 302 ILE A CD1 1 
ATOM 589  N N   . PHE A 1 303 ? 176.048 148.332 132.237 1.00 0.00  ? 303 PHE A N   1 
ATOM 590  C CA  . PHE A 1 303 ? 176.146 147.196 133.146 1.00 2.74  ? 303 PHE A CA  1 
ATOM 591  C C   . PHE A 1 303 ? 176.296 145.863 132.423 1.00 2.50  ? 303 PHE A C   1 
ATOM 592  O O   . PHE A 1 303 ? 176.449 144.835 133.091 1.00 0.14  ? 303 PHE A O   1 
ATOM 593  C CB  . PHE A 1 303 ? 174.918 147.143 134.063 1.00 4.26  ? 303 PHE A CB  1 
ATOM 594  C CG  . PHE A 1 303 ? 175.016 148.037 135.267 1.00 0.36  ? 303 PHE A CG  1 
ATOM 595  C CD1 . PHE A 1 303 ? 175.727 147.637 136.388 1.00 0.40  ? 303 PHE A CD1 1 
ATOM 596  C CD2 . PHE A 1 303 ? 174.397 149.275 135.280 1.00 1.02  ? 303 PHE A CD2 1 
ATOM 597  C CE1 . PHE A 1 303 ? 175.816 148.456 137.501 1.00 0.00  ? 303 PHE A CE1 1 
ATOM 598  C CE2 . PHE A 1 303 ? 174.483 150.100 136.389 1.00 1.36  ? 303 PHE A CE2 1 
ATOM 599  C CZ  . PHE A 1 303 ? 175.195 149.691 137.500 1.00 0.00  ? 303 PHE A CZ  1 
ATOM 600  N N   . GLU A 1 304 ? 176.244 145.858 131.090 1.00 7.89  ? 304 GLU A N   1 
ATOM 601  C CA  . GLU A 1 304 ? 176.362 144.645 130.276 1.00 4.19  ? 304 GLU A CA  1 
ATOM 602  C C   . GLU A 1 304 ? 175.270 143.636 130.624 1.00 4.55  ? 304 GLU A C   1 
ATOM 603  O O   . GLU A 1 304 ? 175.528 142.454 130.856 1.00 8.57  ? 304 GLU A O   1 
ATOM 604  C CB  . GLU A 1 304 ? 177.752 144.020 130.415 1.00 2.80  ? 304 GLU A CB  1 
ATOM 605  C CG  . GLU A 1 304 ? 178.876 144.885 129.880 1.00 5.30  ? 304 GLU A CG  1 
ATOM 606  C CD  . GLU A 1 304 ? 179.844 144.113 129.007 1.00 12.06 ? 304 GLU A CD  1 
ATOM 607  O OE1 . GLU A 1 304 ? 180.695 144.753 128.354 1.00 9.89  ? 304 GLU A OE1 1 
ATOM 608  O OE2 . GLU A 1 304 ? 179.754 142.867 128.970 1.00 12.71 ? 304 GLU A OE2 1 
ATOM 609  N N   . LEU A 1 305 ? 174.030 144.116 130.646 1.00 4.42  ? 305 LEU A N   1 
ATOM 610  C CA  . LEU A 1 305 ? 172.870 143.291 130.945 1.00 2.71  ? 305 LEU A CA  1 
ATOM 611  C C   . LEU A 1 305 ? 172.060 143.072 129.674 1.00 6.14  ? 305 LEU A C   1 
ATOM 612  O O   . LEU A 1 305 ? 172.278 143.738 128.657 1.00 12.71 ? 305 LEU A O   1 
ATOM 613  C CB  . LEU A 1 305 ? 171.991 143.936 132.023 1.00 5.31  ? 305 LEU A CB  1 
ATOM 614  C CG  . LEU A 1 305 ? 172.608 144.102 133.413 1.00 2.32  ? 305 LEU A CG  1 
ATOM 615  C CD1 . LEU A 1 305 ? 171.687 144.908 134.312 1.00 2.50  ? 305 LEU A CD1 1 
ATOM 616  C CD2 . LEU A 1 305 ? 172.925 142.755 134.038 1.00 7.70  ? 305 LEU A CD2 1 
ATOM 617  N N   . ASN A 1 306 ? 171.125 142.131 129.740 1.00 4.19  ? 306 ASN A N   1 
ATOM 618  C CA  . ASN A 1 306 ? 170.323 141.793 128.575 1.00 7.17  ? 306 ASN A CA  1 
ATOM 619  C C   . ASN A 1 306 ? 169.441 142.977 128.181 1.00 6.18  ? 306 ASN A C   1 
ATOM 620  O O   . ASN A 1 306 ? 168.738 143.530 129.038 1.00 6.11  ? 306 ASN A O   1 
ATOM 621  C CB  . ASN A 1 306 ? 169.451 140.569 128.862 1.00 7.89  ? 306 ASN A CB  1 
ATOM 622  C CG  . ASN A 1 306 ? 170.185 139.502 129.647 1.00 10.28 ? 306 ASN A CG  1 
ATOM 623  O OD1 . ASN A 1 306 ? 170.829 139.791 130.655 1.00 10.68 ? 306 ASN A OD1 1 
ATOM 624  N ND2 . ASN A 1 306 ? 170.091 138.259 129.189 1.00 7.98  ? 306 ASN A ND2 1 
ATOM 625  N N   . PRO A 1 307 ? 169.411 143.442 126.903 1.00 9.56  ? 307 PRO A N   1 
ATOM 626  C CA  . PRO A 1 307 ? 168.623 144.621 126.570 1.00 6.02  ? 307 PRO A CA  1 
ATOM 627  C C   . PRO A 1 307 ? 167.205 144.491 127.101 1.00 6.20  ? 307 PRO A C   1 
ATOM 628  O O   . PRO A 1 307 ? 166.559 145.524 127.364 1.00 6.56  ? 307 PRO A O   1 
ATOM 629  C CB  . PRO A 1 307 ? 168.660 144.667 125.037 1.00 4.24  ? 307 PRO A CB  1 
ATOM 630  C CG  . PRO A 1 307 ? 169.974 144.014 124.693 1.00 5.05  ? 307 PRO A CG  1 
ATOM 631  C CD  . PRO A 1 307 ? 170.084 142.892 125.707 1.00 4.24  ? 307 PRO A CD  1 
ATOM 632  N N   . ARG A 1 308 ? 166.730 143.253 127.264 1.00 7.35  ? 308 ARG A N   1 
ATOM 633  C CA  . ARG A 1 308 ? 165.333 143.024 127.717 1.00 9.13  ? 308 ARG A CA  1 
ATOM 634  C C   . ARG A 1 308 ? 165.334 142.163 128.988 1.00 8.36  ? 308 ARG A C   1 
ATOM 635  O O   . ARG A 1 308 ? 166.430 141.900 129.525 1.00 10.12 ? 308 ARG A O   1 
ATOM 636  C CB  . ARG A 1 308 ? 164.537 142.343 126.599 1.00 7.09  ? 308 ARG A CB  1 
ATOM 637  C CG  . ARG A 1 308 ? 164.322 143.220 125.373 1.00 8.58  ? 308 ARG A CG  1 
ATOM 638  C CD  . ARG A 1 308 ? 163.489 142.549 124.290 1.00 8.85  ? 308 ARG A CD  1 
ATOM 639  N NE  . ARG A 1 308 ? 163.340 143.367 123.081 1.00 12.52 ? 308 ARG A NE  1 
ATOM 640  C CZ  . ARG A 1 308 ? 162.756 142.944 121.968 1.00 10.01 ? 308 ARG A CZ  1 
ATOM 641  N NH1 . ARG A 1 308 ? 162.587 141.650 121.765 1.00 9.48  ? 308 ARG A NH1 1 
ATOM 642  N NH2 . ARG A 1 308 ? 162.345 143.811 121.063 1.00 8.23  ? 308 ARG A NH2 1 
ATOM 643  N N   . SER A 1 309 ? 164.150 141.741 129.445 1.00 4.05  ? 309 SER A N   1 
ATOM 644  C CA  . SER A 1 309 ? 164.038 140.918 130.680 1.00 9.40  ? 309 SER A CA  1 
ATOM 645  C C   . SER A 1 309 ? 164.976 141.470 131.764 1.00 11.13 ? 309 SER A C   1 
ATOM 646  O O   . SER A 1 309 ? 165.829 140.702 132.261 1.00 12.60 ? 309 SER A O   1 
ATOM 647  C CB  . SER A 1 309 ? 164.312 139.460 130.398 1.00 10.74 ? 309 SER A CB  1 
ATOM 648  O OG  . SER A 1 309 ? 165.699 139.223 130.201 1.00 13.86 ? 309 SER A OG  1 
ATOM 649  N N   . ASN A 1 310 ? 164.812 142.746 132.123 1.00 4.82  ? 310 ASN A N   1 
ATOM 650  C CA  . ASN A 1 310 ? 165.700 143.379 133.137 1.00 5.08  ? 310 ASN A CA  1 
ATOM 651  C C   . ASN A 1 310 ? 164.851 144.008 134.244 1.00 8.18  ? 310 ASN A C   1 
ATOM 652  O O   . ASN A 1 310 ? 163.793 144.592 133.920 1.00 9.63  ? 310 ASN A O   1 
ATOM 653  C CB  . ASN A 1 310 ? 166.644 144.398 132.507 1.00 8.41  ? 310 ASN A CB  1 
ATOM 654  C CG  . ASN A 1 310 ? 165.911 145.571 131.900 1.00 5.86  ? 310 ASN A CG  1 
ATOM 655  O OD1 . ASN A 1 310 ? 164.871 145.995 132.414 1.00 4.75  ? 310 ASN A OD1 1 
ATOM 656  N ND2 . ASN A 1 310 ? 166.439 146.113 130.813 1.00 5.37  ? 310 ASN A ND2 1 
ATOM 657  N N   . LEU A 1 311 ? 165.296 143.896 135.499 1.00 4.95  ? 311 LEU A N   1 
ATOM 658  C CA  . LEU A 1 311 ? 164.579 144.498 136.614 1.00 1.86  ? 311 LEU A CA  1 
ATOM 659  C C   . LEU A 1 311 ? 164.283 145.970 136.354 1.00 8.54  ? 311 LEU A C   1 
ATOM 660  O O   . LEU A 1 311 ? 165.149 146.727 135.907 1.00 11.76 ? 311 LEU A O   1 
ATOM 661  C CB  . LEU A 1 311 ? 165.382 144.356 137.907 1.00 6.73  ? 311 LEU A CB  1 
ATOM 662  C CG  . LEU A 1 311 ? 165.261 143.022 138.646 1.00 8.22  ? 311 LEU A CG  1 
ATOM 663  C CD1 . LEU A 1 311 ? 165.674 143.175 140.102 1.00 3.50  ? 311 LEU A CD1 1 
ATOM 664  C CD2 . LEU A 1 311 ? 163.853 142.453 138.535 1.00 5.88  ? 311 LEU A CD2 1 
ATOM 665  N N   . SER A 1 312 ? 163.046 146.369 136.637 1.00 5.59  ? 312 SER A N   1 
ATOM 666  C CA  . SER A 1 312 ? 162.662 147.769 136.583 1.00 1.89  ? 312 SER A CA  1 
ATOM 667  C C   . SER A 1 312 ? 162.731 148.386 137.979 1.00 3.72  ? 312 SER A C   1 
ATOM 668  O O   . SER A 1 312 ? 163.026 147.715 138.971 1.00 2.41  ? 312 SER A O   1 
ATOM 669  C CB  . SER A 1 312 ? 161.260 147.918 135.990 1.00 4.87  ? 312 SER A CB  1 
ATOM 670  O OG  . SER A 1 312 ? 160.264 147.499 136.906 1.00 5.67  ? 312 SER A OG  1 
ATOM 671  N N   . HIS A 1 313 ? 162.468 149.693 138.047 1.00 2.63  ? 313 HIS A N   1 
ATOM 672  C CA  . HIS A 1 313 ? 162.503 150.377 139.336 1.00 1.17  ? 313 HIS A CA  1 
ATOM 673  C C   . HIS A 1 313 ? 161.371 149.918 140.248 1.00 1.62  ? 313 HIS A C   1 
ATOM 674  O O   . HIS A 1 313 ? 161.527 149.910 141.476 1.00 2.38  ? 313 HIS A O   1 
ATOM 675  C CB  . HIS A 1 313 ? 162.462 151.893 139.129 1.00 0.00  ? 313 HIS A CB  1 
ATOM 676  C CG  . HIS A 1 313 ? 161.208 152.388 138.478 1.00 2.30  ? 313 HIS A CG  1 
ATOM 677  N ND1 . HIS A 1 313 ? 161.057 152.453 137.110 1.00 3.92  ? 313 HIS A ND1 1 
ATOM 678  C CD2 . HIS A 1 313 ? 160.055 152.860 139.006 1.00 4.51  ? 313 HIS A CD2 1 
ATOM 679  C CE1 . HIS A 1 313 ? 159.861 152.935 136.824 1.00 2.94  ? 313 HIS A CE1 1 
ATOM 680  N NE2 . HIS A 1 313 ? 159.233 153.190 137.957 1.00 3.48  ? 313 HIS A NE2 1 
ATOM 681  N N   . GLN A 1 314 ? 160.235 149.518 139.670 1.00 2.31  ? 314 GLN A N   1 
ATOM 682  C CA  . GLN A 1 314 ? 159.136 148.998 140.477 1.00 1.84  ? 314 GLN A CA  1 
ATOM 683  C C   . GLN A 1 314 ? 159.533 147.713 141.192 1.00 0.98  ? 314 GLN A C   1 
ATOM 684  O O   . GLN A 1 314 ? 159.129 147.483 142.334 1.00 0.91  ? 314 GLN A O   1 
ATOM 685  C CB  . GLN A 1 314 ? 157.902 148.764 139.606 1.00 1.70  ? 314 GLN A CB  1 
ATOM 686  C CG  . GLN A 1 314 ? 157.777 149.704 138.421 1.00 2.52  ? 314 GLN A CG  1 
ATOM 687  C CD  . GLN A 1 314 ? 157.050 150.987 138.768 1.00 8.64  ? 314 GLN A CD  1 
ATOM 688  O OE1 . GLN A 1 314 ? 157.232 151.545 139.849 1.00 7.31  ? 314 GLN A OE1 1 
ATOM 689  N NE2 . GLN A 1 314 ? 156.219 151.463 137.848 1.00 8.75  ? 314 GLN A NE2 1 
ATOM 690  N N   . HIS A 1 315 ? 160.317 146.856 140.534 1.00 0.00  ? 315 HIS A N   1 
ATOM 691  C CA  . HIS A 1 315 ? 160.752 145.619 141.176 1.00 0.00  ? 315 HIS A CA  1 
ATOM 692  C C   . HIS A 1 315 ? 161.678 145.898 142.355 1.00 2.33  ? 315 HIS A C   1 
ATOM 693  O O   . HIS A 1 315 ? 161.576 145.244 143.403 1.00 2.03  ? 315 HIS A O   1 
ATOM 694  C CB  . HIS A 1 315 ? 161.429 144.712 140.151 1.00 2.32  ? 315 HIS A CB  1 
ATOM 695  C CG  . HIS A 1 315 ? 160.504 144.222 139.083 1.00 7.28  ? 315 HIS A CG  1 
ATOM 696  N ND1 . HIS A 1 315 ? 160.502 144.738 137.805 1.00 6.24  ? 315 HIS A ND1 1 
ATOM 697  C CD2 . HIS A 1 315 ? 159.540 143.272 139.106 1.00 3.01  ? 315 HIS A CD2 1 
ATOM 698  C CE1 . HIS A 1 315 ? 159.582 144.123 137.085 1.00 5.96  ? 315 HIS A CE1 1 
ATOM 699  N NE2 . HIS A 1 315 ? 158.983 143.228 137.851 1.00 4.86  ? 315 HIS A NE2 1 
ATOM 700  N N   . LEU A 1 316 ? 162.587 146.864 142.204 1.00 0.72  ? 316 LEU A N   1 
ATOM 701  C CA  . LEU A 1 316 ? 163.440 147.256 143.319 1.00 2.34  ? 316 LEU A CA  1 
ATOM 702  C C   . LEU A 1 316 ? 162.619 147.854 144.455 1.00 0.73  ? 316 LEU A C   1 
ATOM 703  O O   . LEU A 1 316 ? 162.883 147.576 145.630 1.00 0.00  ? 316 LEU A O   1 
ATOM 704  C CB  . LEU A 1 316 ? 164.512 148.238 142.844 1.00 1.09  ? 316 LEU A CB  1 
ATOM 705  C CG  . LEU A 1 316 ? 165.646 147.623 142.020 1.00 1.36  ? 316 LEU A CG  1 
ATOM 706  C CD1 . LEU A 1 316 ? 166.397 148.689 141.236 1.00 2.05  ? 316 LEU A CD1 1 
ATOM 707  C CD2 . LEU A 1 316 ? 166.594 146.841 142.912 1.00 2.84  ? 316 LEU A CD2 1 
ATOM 708  N N   . PHE A 1 317 ? 161.615 148.672 144.124 1.00 0.00  ? 317 PHE A N   1 
ATOM 709  C CA  . PHE A 1 317 ? 160.720 149.195 145.154 1.00 1.98  ? 317 PHE A CA  1 
ATOM 710  C C   . PHE A 1 317 ? 159.985 148.066 145.869 1.00 0.00  ? 317 PHE A C   1 
ATOM 711  O O   . PHE A 1 317 ? 159.799 148.110 147.088 1.00 0.00  ? 317 PHE A O   1 
ATOM 712  C CB  . PHE A 1 317 ? 159.721 150.179 144.541 1.00 1.82  ? 317 PHE A CB  1 
ATOM 713  C CG  . PHE A 1 317 ? 160.338 151.472 144.078 1.00 1.49  ? 317 PHE A CG  1 
ATOM 714  C CD1 . PHE A 1 317 ? 161.413 152.028 144.754 1.00 2.57  ? 317 PHE A CD1 1 
ATOM 715  C CD2 . PHE A 1 317 ? 159.835 152.134 142.970 1.00 0.00  ? 317 PHE A CD2 1 
ATOM 716  C CE1 . PHE A 1 317 ? 161.979 153.215 144.329 1.00 1.65  ? 317 PHE A CE1 1 
ATOM 717  C CE2 . PHE A 1 317 ? 160.397 153.324 142.539 1.00 1.04  ? 317 PHE A CE2 1 
ATOM 718  C CZ  . PHE A 1 317 ? 161.471 153.865 143.220 1.00 1.81  ? 317 PHE A CZ  1 
ATOM 719  N N   . GLU A 1 318 ? 159.568 147.041 145.123 1.00 0.00  ? 318 GLU A N   1 
ATOM 720  C CA  . GLU A 1 318 ? 158.871 145.902 145.714 1.00 1.52  ? 318 GLU A CA  1 
ATOM 721  C C   . GLU A 1 318 ? 159.769 145.145 146.686 1.00 3.23  ? 318 GLU A C   1 
ATOM 722  O O   . GLU A 1 318 ? 159.362 144.826 147.813 1.00 0.00  ? 318 GLU A O   1 
ATOM 723  C CB  . GLU A 1 318 ? 158.377 144.975 144.603 1.00 2.70  ? 318 GLU A CB  1 
ATOM 724  C CG  . GLU A 1 318 ? 157.736 143.688 145.083 1.00 2.95  ? 318 GLU A CG  1 
ATOM 725  C CD  . GLU A 1 318 ? 156.809 143.084 144.046 1.00 6.32  ? 318 GLU A CD  1 
ATOM 726  O OE1 . GLU A 1 318 ? 156.465 141.892 144.177 1.00 9.91  ? 318 GLU A OE1 1 
ATOM 727  O OE2 . GLU A 1 318 ? 156.419 143.803 143.104 1.00 8.53  ? 318 GLU A OE2 1 
ATOM 728  N N   . ILE A 1 319 ? 160.996 144.838 146.258 1.00 1.33  ? 319 ILE A N   1 
ATOM 729  C CA  . ILE A 1 319 ? 161.927 144.122 147.127 1.00 0.00  ? 319 ILE A CA  1 
ATOM 730  C C   . ILE A 1 319 ? 162.241 144.952 148.365 1.00 0.40  ? 319 ILE A C   1 
ATOM 731  O O   . ILE A 1 319 ? 162.266 144.434 149.490 1.00 0.00  ? 319 ILE A O   1 
ATOM 732  C CB  . ILE A 1 319 ? 163.206 143.746 146.355 1.00 1.14  ? 319 ILE A CB  1 
ATOM 733  C CG1 . ILE A 1 319 ? 162.878 142.800 145.200 1.00 6.40  ? 319 ILE A CG1 1 
ATOM 734  C CG2 . ILE A 1 319 ? 164.224 143.104 147.283 1.00 2.94  ? 319 ILE A CG2 1 
ATOM 735  C CD1 . ILE A 1 319 ? 163.832 142.907 144.029 1.00 4.44  ? 319 ILE A CD1 1 
ATOM 736  N N   . ALA A 1 320 ? 162.475 146.255 148.180 1.00 1.20  ? 320 ALA A N   1 
ATOM 737  C CA  . ALA A 1 320 ? 162.776 147.125 149.310 1.00 0.82  ? 320 ALA A CA  1 
ATOM 738  C C   . ALA A 1 320 ? 161.605 147.197 150.279 1.00 0.54  ? 320 ALA A C   1 
ATOM 739  O O   . ALA A 1 320 ? 161.805 147.187 151.496 1.00 0.00  ? 320 ALA A O   1 
ATOM 740  C CB  . ALA A 1 320 ? 163.155 148.521 148.816 1.00 0.00  ? 320 ALA A CB  1 
ATOM 741  N N   . GLY A 1 321 ? 160.377 147.264 149.762 1.00 0.00  ? 321 GLY A N   1 
ATOM 742  C CA  . GLY A 1 321 ? 159.217 147.292 150.636 1.00 0.00  ? 321 GLY A CA  1 
ATOM 743  C C   . GLY A 1 321 ? 159.038 146.007 151.421 1.00 0.00  ? 321 GLY A C   1 
ATOM 744  O O   . GLY A 1 321 ? 158.749 146.039 152.619 1.00 0.27  ? 321 GLY A O   1 
ATOM 745  N N   . PHE A 1 322 ? 159.212 144.859 150.762 1.00 0.00  ? 322 PHE A N   1 
ATOM 746  C CA  . PHE A 1 322 ? 159.100 143.583 151.463 1.00 0.00  ? 322 PHE A CA  1 
ATOM 747  C C   . PHE A 1 322 ? 160.163 143.456 152.552 1.00 1.56  ? 322 PHE A C   1 
ATOM 748  O O   . PHE A 1 322 ? 159.869 143.046 153.686 1.00 0.78  ? 322 PHE A O   1 
ATOM 749  C CB  . PHE A 1 322 ? 159.205 142.429 150.464 1.00 0.10  ? 322 PHE A CB  1 
ATOM 750  C CG  . PHE A 1 322 ? 159.088 141.070 151.091 1.00 1.91  ? 322 PHE A CG  1 
ATOM 751  C CD1 . PHE A 1 322 ? 157.876 140.623 151.588 1.00 0.44  ? 322 PHE A CD1 1 
ATOM 752  C CD2 . PHE A 1 322 ? 160.192 140.241 151.187 1.00 1.56  ? 322 PHE A CD2 1 
ATOM 753  C CE1 . PHE A 1 322 ? 157.768 139.375 152.167 1.00 0.72  ? 322 PHE A CE1 1 
ATOM 754  C CE2 . PHE A 1 322 ? 160.089 138.990 151.765 1.00 3.04  ? 322 PHE A CE2 1 
ATOM 755  C CZ  . PHE A 1 322 ? 158.876 138.557 152.256 1.00 1.55  ? 322 PHE A CZ  1 
ATOM 756  N N   . LEU A 1 323 ? 161.408 143.817 152.230 1.00 0.00  ? 323 LEU A N   1 
ATOM 757  C CA  . LEU A 1 323 ? 162.474 143.730 153.223 1.00 0.00  ? 323 LEU A CA  1 
ATOM 758  C C   . LEU A 1 323 ? 162.258 144.729 154.352 1.00 0.00  ? 323 LEU A C   1 
ATOM 759  O O   . LEU A 1 323 ? 162.560 144.433 155.512 1.00 0.00  ? 323 LEU A O   1 
ATOM 760  C CB  . LEU A 1 323 ? 163.836 143.939 152.561 1.00 0.64  ? 323 LEU A CB  1 
ATOM 761  C CG  . LEU A 1 323 ? 164.307 142.820 151.628 1.00 0.60  ? 323 LEU A CG  1 
ATOM 762  C CD1 . LEU A 1 323 ? 165.771 143.002 151.259 1.00 2.81  ? 323 LEU A CD1 1 
ATOM 763  C CD2 . LEU A 1 323 ? 164.076 141.453 152.256 1.00 0.00  ? 323 LEU A CD2 1 
ATOM 764  N N   . GLY A 1 324 ? 161.736 145.914 154.036 1.00 0.00  ? 324 GLY A N   1 
ATOM 765  C CA  . GLY A 1 324 ? 161.409 146.867 155.079 1.00 0.26  ? 324 GLY A CA  1 
ATOM 766  C C   . GLY A 1 324 ? 160.311 146.364 155.993 1.00 0.00  ? 324 GLY A C   1 
ATOM 767  O O   . GLY A 1 324 ? 160.344 146.597 157.200 1.00 0.00  ? 324 GLY A O   1 
ATOM 768  N N   . ILE A 1 325 ? 159.329 145.657 155.428 1.00 2.32  ? 325 ILE A N   1 
ATOM 769  C CA  . ILE A 1 325 ? 158.280 145.052 156.245 1.00 1.10  ? 325 ILE A CA  1 
ATOM 770  C C   . ILE A 1 325 ? 158.875 144.017 157.189 1.00 0.00  ? 325 ILE A C   1 
ATOM 771  O O   . ILE A 1 325 ? 158.543 143.972 158.379 1.00 1.71  ? 325 ILE A O   1 
ATOM 772  C CB  . ILE A 1 325 ? 157.191 144.432 155.351 1.00 2.53  ? 325 ILE A CB  1 
ATOM 773  C CG1 . ILE A 1 325 ? 156.309 145.521 154.744 1.00 0.70  ? 325 ILE A CG1 1 
ATOM 774  C CG2 . ILE A 1 325 ? 156.349 143.439 156.140 1.00 0.00  ? 325 ILE A CG2 1 
ATOM 775  C CD1 . ILE A 1 325 ? 155.398 145.010 153.660 1.00 3.39  ? 325 ILE A CD1 1 
ATOM 776  N N   . LEU A 1 326 ? 159.756 143.160 156.668 1.00 0.00  ? 326 LEU A N   1 
ATOM 777  C CA  . LEU A 1 326 ? 160.373 142.147 157.523 1.00 0.02  ? 326 LEU A CA  1 
ATOM 778  C C   . LEU A 1 326 ? 161.233 142.784 158.610 1.00 2.30  ? 326 LEU A C   1 
ATOM 779  O O   . LEU A 1 326 ? 161.219 142.341 159.764 1.00 0.60  ? 326 LEU A O   1 
ATOM 780  C CB  . LEU A 1 326 ? 161.192 141.171 156.682 1.00 1.14  ? 326 LEU A CB  1 
ATOM 781  C CG  . LEU A 1 326 ? 160.378 140.095 155.962 1.00 3.75  ? 326 LEU A CG  1 
ATOM 782  C CD1 . LEU A 1 326 ? 161.283 138.978 155.487 1.00 3.21  ? 326 LEU A CD1 1 
ATOM 783  C CD2 . LEU A 1 326 ? 159.277 139.547 156.859 1.00 1.86  ? 326 LEU A CD2 1 
ATOM 784  N N   . TRP A 1 327 ? 161.982 143.831 158.258 1.00 3.46  ? 327 TRP A N   1 
ATOM 785  C CA  . TRP A 1 327 ? 162.794 144.551 159.234 1.00 0.00  ? 327 TRP A CA  1 
ATOM 786  C C   . TRP A 1 327 ? 161.924 145.194 160.310 1.00 0.00  ? 327 TRP A C   1 
ATOM 787  O O   . TRP A 1 327 ? 162.240 145.120 161.505 1.00 0.00  ? 327 TRP A O   1 
ATOM 788  C CB  . TRP A 1 327 ? 163.635 145.597 158.500 1.00 0.00  ? 327 TRP A CB  1 
ATOM 789  C CG  . TRP A 1 327 ? 164.561 146.419 159.339 1.00 0.00  ? 327 TRP A CG  1 
ATOM 790  C CD1 . TRP A 1 327 ? 165.847 146.117 159.682 1.00 0.00  ? 327 TRP A CD1 1 
ATOM 791  C CD2 . TRP A 1 327 ? 164.289 147.707 159.903 1.00 1.48  ? 327 TRP A CD2 1 
ATOM 792  N NE1 . TRP A 1 327 ? 166.385 147.127 160.440 1.00 0.00  ? 327 TRP A NE1 1 
ATOM 793  C CE2 . TRP A 1 327 ? 165.450 148.117 160.588 1.00 0.08  ? 327 TRP A CE2 1 
ATOM 794  C CE3 . TRP A 1 327 ? 163.173 148.551 159.900 1.00 0.00  ? 327 TRP A CE3 1 
ATOM 795  C CZ2 . TRP A 1 327 ? 165.528 149.332 161.267 1.00 0.00  ? 327 TRP A CZ2 1 
ATOM 796  C CZ3 . TRP A 1 327 ? 163.252 149.757 160.576 1.00 0.00  ? 327 TRP A CZ3 1 
ATOM 797  C CH2 . TRP A 1 327 ? 164.421 150.136 161.249 1.00 0.00  ? 327 TRP A CH2 1 
ATOM 798  N N   . CYS A 1 328 ? 160.816 145.816 159.901 1.00 1.11  ? 328 CYS A N   1 
ATOM 799  C CA  . CYS A 1 328 ? 159.899 146.432 160.854 1.00 0.57  ? 328 CYS A CA  1 
ATOM 800  C C   . CYS A 1 328 ? 159.287 145.394 161.781 1.00 0.91  ? 328 CYS A C   1 
ATOM 801  O O   . CYS A 1 328 ? 159.171 145.627 162.985 1.00 0.00  ? 328 CYS A O   1 
ATOM 802  C CB  . CYS A 1 328 ? 158.800 147.192 160.112 1.00 2.46  ? 328 CYS A CB  1 
ATOM 803  S SG  . CYS A 1 328 ? 159.217 148.890 159.665 1.00 8.84  ? 328 CYS A SG  1 
ATOM 804  N N   . LEU A 1 329 ? 158.884 144.243 161.238 1.00 2.99  ? 329 LEU A N   1 
ATOM 805  C CA  . LEU A 1 329 ? 158.305 143.194 162.072 1.00 0.79  ? 329 LEU A CA  1 
ATOM 806  C C   . LEU A 1 329 ? 159.328 142.634 163.052 1.00 0.00  ? 329 LEU A C   1 
ATOM 807  O O   . LEU A 1 329 ? 159.001 142.372 164.215 1.00 0.00  ? 329 LEU A O   1 
ATOM 808  C CB  . LEU A 1 329 ? 157.733 142.078 161.199 1.00 4.30  ? 329 LEU A CB  1 
ATOM 809  C CG  . LEU A 1 329 ? 156.450 142.410 160.436 1.00 2.94  ? 329 LEU A CG  1 
ATOM 810  C CD1 . LEU A 1 329 ? 156.032 141.240 159.563 1.00 0.56  ? 329 LEU A CD1 1 
ATOM 811  C CD2 . LEU A 1 329 ? 155.334 142.800 161.398 1.00 2.75  ? 329 LEU A CD2 1 
ATOM 812  N N   . SER A 1 330 ? 160.570 142.439 162.600 1.00 0.80  ? 330 SER A N   1 
ATOM 813  C CA  . SER A 1 330 ? 161.611 141.945 163.493 1.00 1.08  ? 330 SER A CA  1 
ATOM 814  C C   . SER A 1 330 ? 161.879 142.932 164.623 1.00 3.48  ? 330 SER A C   1 
ATOM 815  O O   . SER A 1 330 ? 161.991 142.538 165.792 1.00 1.82  ? 330 SER A O   1 
ATOM 816  C CB  . SER A 1 330 ? 162.887 141.666 162.698 1.00 2.91  ? 330 SER A CB  1 
ATOM 817  O OG  . SER A 1 330 ? 163.968 141.336 163.549 1.00 7.31  ? 330 SER A OG  1 
ATOM 818  N N   . LEU A 1 331 ? 161.957 144.226 164.299 1.00 0.60  ? 331 LEU A N   1 
ATOM 819  C CA  . LEU A 1 331 ? 162.158 145.231 165.338 1.00 0.61  ? 331 LEU A CA  1 
ATOM 820  C C   . LEU A 1 331 ? 160.954 145.321 166.271 1.00 2.35  ? 331 LEU A C   1 
ATOM 821  O O   . LEU A 1 331 ? 161.115 145.501 167.483 1.00 6.19  ? 331 LEU A O   1 
ATOM 822  C CB  . LEU A 1 331 ? 162.450 146.590 164.708 1.00 3.70  ? 331 LEU A CB  1 
ATOM 823  C CG  . LEU A 1 331 ? 163.869 147.110 164.927 1.00 2.67  ? 331 LEU A CG  1 
ATOM 824  C CD1 . LEU A 1 331 ? 164.027 148.498 164.340 1.00 0.32  ? 331 LEU A CD1 1 
ATOM 825  C CD2 . LEU A 1 331 ? 164.207 147.106 166.402 1.00 1.53  ? 331 LEU A CD2 1 
ATOM 826  N N   . LEU A 1 332 ? 159.741 145.206 165.725 1.00 3.54  ? 332 LEU A N   1 
ATOM 827  C CA  . LEU A 1 332 ? 158.542 145.272 166.552 1.00 2.47  ? 332 LEU A CA  1 
ATOM 828  C C   . LEU A 1 332 ? 158.483 144.105 167.524 1.00 3.07  ? 332 LEU A C   1 
ATOM 829  O O   . LEU A 1 332 ? 158.086 144.274 168.680 1.00 5.99  ? 332 LEU A O   1 
ATOM 830  C CB  . LEU A 1 332 ? 157.291 145.301 165.672 1.00 3.89  ? 332 LEU A CB  1 
ATOM 831  C CG  . LEU A 1 332 ? 156.933 146.643 165.029 1.00 4.77  ? 332 LEU A CG  1 
ATOM 832  C CD1 . LEU A 1 332 ? 156.086 146.432 163.783 1.00 2.34  ? 332 LEU A CD1 1 
ATOM 833  C CD2 . LEU A 1 332 ? 156.226 147.558 166.014 1.00 3.20  ? 332 LEU A CD2 1 
ATOM 834  N N   . ALA A 1 333 ? 158.864 142.910 167.074 1.00 6.07  ? 333 ALA A N   1 
ATOM 835  C CA  . ALA A 1 333 ? 158.941 141.776 167.989 1.00 2.65  ? 333 ALA A CA  1 
ATOM 836  C C   . ALA A 1 333 ? 160.016 142.000 169.045 1.00 2.12  ? 333 ALA A C   1 
ATOM 837  O O   . ALA A 1 333 ? 159.784 141.777 170.240 1.00 9.13  ? 333 ALA A O   1 
ATOM 838  C CB  . ALA A 1 333 ? 159.201 140.490 167.210 1.00 1.76  ? 333 ALA A CB  1 
ATOM 839  N N   . CYS A 1 334 ? 161.196 142.466 168.625 1.00 6.57  ? 334 CYS A N   1 
ATOM 840  C CA  . CYS A 1 334 ? 162.270 142.759 169.567 1.00 5.96  ? 334 CYS A CA  1 
ATOM 841  C C   . CYS A 1 334 ? 161.859 143.784 170.615 1.00 6.59  ? 334 CYS A C   1 
ATOM 842  O O   . CYS A 1 334 ? 162.373 143.744 171.738 1.00 9.48  ? 334 CYS A O   1 
ATOM 843  C CB  . CYS A 1 334 ? 163.502 143.255 168.804 1.00 3.65  ? 334 CYS A CB  1 
ATOM 844  S SG  . CYS A 1 334 ? 165.080 142.957 169.620 1.00 24.48 ? 334 CYS A SG  1 
ATOM 845  N N   . PHE A 1 335 ? 160.948 144.691 170.275 1.00 8.90  ? 335 PHE A N   1 
ATOM 846  C CA  . PHE A 1 335 ? 160.460 145.695 171.205 1.00 4.09  ? 335 PHE A CA  1 
ATOM 847  C C   . PHE A 1 335 ? 159.276 145.234 172.044 1.00 8.29  ? 335 PHE A C   1 
ATOM 848  O O   . PHE A 1 335 ? 159.152 145.669 173.194 1.00 10.02 ? 335 PHE A O   1 
ATOM 849  C CB  . PHE A 1 335 ? 160.062 146.968 170.443 1.00 4.80  ? 335 PHE A CB  1 
ATOM 850  C CG  . PHE A 1 335 ? 161.232 147.784 169.980 1.00 3.35  ? 335 PHE A CG  1 
ATOM 851  C CD1 . PHE A 1 335 ? 162.463 147.668 170.603 1.00 7.53  ? 335 PHE A CD1 1 
ATOM 852  C CD2 . PHE A 1 335 ? 161.107 148.655 168.913 1.00 5.11  ? 335 PHE A CD2 1 
ATOM 853  C CE1 . PHE A 1 335 ? 163.542 148.416 170.177 1.00 8.73  ? 335 PHE A CE1 1 
ATOM 854  C CE2 . PHE A 1 335 ? 162.182 149.404 168.483 1.00 6.54  ? 335 PHE A CE2 1 
ATOM 855  C CZ  . PHE A 1 335 ? 163.401 149.284 169.115 1.00 5.31  ? 335 PHE A CZ  1 
ATOM 856  N N   . PHE A 1 336 ? 158.409 144.376 171.510 1.00 8.84  ? 336 PHE A N   1 
ATOM 857  C CA  . PHE A 1 336 ? 157.176 143.979 172.174 1.00 7.15  ? 336 PHE A CA  1 
ATOM 858  C C   . PHE A 1 336 ? 157.292 142.662 172.926 1.00 7.56  ? 336 PHE A C   1 
ATOM 859  O O   . PHE A 1 336 ? 156.320 142.254 173.569 1.00 5.54  ? 336 PHE A O   1 
ATOM 860  C CB  . PHE A 1 336 ? 156.041 143.882 171.149 1.00 4.48  ? 336 PHE A CB  1 
ATOM 861  C CG  . PHE A 1 336 ? 155.556 145.213 170.656 1.00 7.88  ? 336 PHE A CG  1 
ATOM 862  C CD1 . PHE A 1 336 ? 155.730 146.355 171.418 1.00 8.24  ? 336 PHE A CD1 1 
ATOM 863  C CD2 . PHE A 1 336 ? 154.932 145.324 169.425 1.00 7.66  ? 336 PHE A CD2 1 
ATOM 864  C CE1 . PHE A 1 336 ? 155.287 147.582 170.966 1.00 6.77  ? 336 PHE A CE1 1 
ATOM 865  C CE2 . PHE A 1 336 ? 154.485 146.550 168.967 1.00 8.25  ? 336 PHE A CE2 1 
ATOM 866  C CZ  . PHE A 1 336 ? 154.663 147.679 169.738 1.00 5.47  ? 336 PHE A CZ  1 
ATOM 867  N N   . ALA A 1 337 ? 158.449 141.992 172.864 1.00 9.11  ? 337 ALA A N   1 
ATOM 868  C CA  . ALA A 1 337 ? 158.678 140.767 173.627 1.00 6.99  ? 337 ALA A CA  1 
ATOM 869  C C   . ALA A 1 337 ? 157.599 139.725 173.348 1.00 8.19  ? 337 ALA A C   1 
ATOM 870  O O   . ALA A 1 337 ? 156.737 139.474 174.199 1.00 10.83 ? 337 ALA A O   1 
ATOM 871  C CB  . ALA A 1 337 ? 158.748 141.070 175.125 1.00 5.35  ? 337 ALA A CB  1 
ATOM 872  N N   . PRO A 1 338 ? 157.617 139.103 172.173 1.00 7.14  ? 338 PRO A N   1 
ATOM 873  C CA  . PRO A 1 338 ? 156.596 138.104 171.838 1.00 9.55  ? 338 PRO A CA  1 
ATOM 874  C C   . PRO A 1 338 ? 156.810 136.793 172.580 1.00 12.60 ? 338 PRO A C   1 
ATOM 875  O O   . PRO A 1 338 ? 157.632 136.732 173.501 1.00 14.83 ? 338 PRO A O   1 
ATOM 876  C CB  . PRO A 1 338 ? 156.751 137.945 170.321 1.00 8.94  ? 338 PRO A CB  1 
ATOM 877  C CG  . PRO A 1 338 ? 158.180 138.298 170.046 1.00 7.26  ? 338 PRO A CG  1 
ATOM 878  C CD  . PRO A 1 338 ? 158.715 139.117 171.193 1.00 9.66  ? 338 PRO A CD  1 
ATOM 879  N N   . ILE A 1 339 ? 156.058 135.757 172.196 1.00 11.23 ? 339 ILE A N   1 
ATOM 880  C CA  . ILE A 1 339 ? 155.964 134.482 172.909 1.00 6.97  ? 339 ILE A CA  1 
ATOM 881  C C   . ILE A 1 339 ? 157.318 134.014 173.438 1.00 8.87  ? 339 ILE A C   1 
ATOM 882  O O   . ILE A 1 339 ? 158.322 134.004 172.716 1.00 7.00  ? 339 ILE A O   1 
ATOM 883  C CB  . ILE A 1 339 ? 155.297 133.423 172.006 1.00 8.89  ? 339 ILE A CB  1 
ATOM 884  C CG1 . ILE A 1 339 ? 156.116 133.166 170.741 1.00 6.32  ? 339 ILE A CG1 1 
ATOM 885  C CG2 . ILE A 1 339 ? 153.886 133.851 171.634 1.00 10.12 ? 339 ILE A CG2 1 
ATOM 886  C CD1 . ILE A 1 339 ? 156.382 131.709 170.478 1.00 9.24  ? 339 ILE A CD1 1 
ATOM 887  N N   . SER A 1 340 ? 157.346 133.649 174.724 1.00 13.17 ? 340 SER A N   1 
ATOM 888  C CA  . SER A 1 340 ? 158.600 133.611 175.472 1.00 8.04  ? 340 SER A CA  1 
ATOM 889  C C   . SER A 1 340 ? 159.451 132.398 175.123 1.00 9.95  ? 340 SER A C   1 
ATOM 890  O O   . SER A 1 340 ? 160.635 132.345 175.474 1.00 14.46 ? 340 SER A O   1 
ATOM 891  C CB  . SER A 1 340 ? 158.313 133.639 176.974 1.00 9.87  ? 340 SER A CB  1 
ATOM 892  O OG  . SER A 1 340 ? 157.665 132.451 177.394 1.00 14.17 ? 340 SER A OG  1 
ATOM 893  N N   . VAL A 1 341 ? 158.869 131.409 174.450 1.00 7.79  ? 341 VAL A N   1 
ATOM 894  C CA  . VAL A 1 341 ? 159.607 130.198 174.104 1.00 8.23  ? 341 VAL A CA  1 
ATOM 895  C C   . VAL A 1 341 ? 160.778 130.541 173.188 1.00 10.62 ? 341 VAL A C   1 
ATOM 896  O O   . VAL A 1 341 ? 161.839 129.911 173.262 1.00 13.32 ? 341 VAL A O   1 
ATOM 897  C CB  . VAL A 1 341 ? 158.688 129.139 173.469 1.00 8.56  ? 341 VAL A CB  1 
ATOM 898  C CG1 . VAL A 1 341 ? 159.510 127.942 173.009 1.00 7.53  ? 341 VAL A CG1 1 
ATOM 899  C CG2 . VAL A 1 341 ? 157.630 128.689 174.459 1.00 9.50  ? 341 VAL A CG2 1 
ATOM 900  N N   . ILE A 1 342 ? 160.599 131.528 172.316 1.00 7.25  ? 342 ILE A N   1 
ATOM 901  C CA  . ILE A 1 342 ? 161.683 131.980 171.446 1.00 5.86  ? 342 ILE A CA  1 
ATOM 902  C C   . ILE A 1 342 ? 162.277 133.261 172.023 1.00 8.09  ? 342 ILE A C   1 
ATOM 903  O O   . ILE A 1 342 ? 161.573 134.277 172.128 1.00 12.14 ? 342 ILE A O   1 
ATOM 904  C CB  . ILE A 1 342 ? 161.196 132.179 170.002 1.00 7.07  ? 342 ILE A CB  1 
ATOM 905  C CG1 . ILE A 1 342 ? 162.149 133.089 169.230 1.00 10.92 ? 342 ILE A CG1 1 
ATOM 906  C CG2 . ILE A 1 342 ? 159.795 132.748 169.981 1.00 7.44  ? 342 ILE A CG2 1 
ATOM 907  C CD1 . ILE A 1 342 ? 161.799 133.228 167.774 1.00 8.64  ? 342 ILE A CD1 1 
ATOM 908  N N   . PRO A 1 343 ? 163.539 133.251 172.449 1.00 6.82  ? 343 PRO A N   1 
ATOM 909  C CA  . PRO A 1 343 ? 164.167 134.481 172.941 1.00 6.13  ? 343 PRO A CA  1 
ATOM 910  C C   . PRO A 1 343 ? 164.184 135.580 171.888 1.00 9.41  ? 343 PRO A C   1 
ATOM 911  O O   . PRO A 1 343 ? 164.031 135.342 170.688 1.00 10.60 ? 343 PRO A O   1 
ATOM 912  C CB  . PRO A 1 343 ? 165.595 134.031 173.282 1.00 6.85  ? 343 PRO A CB  1 
ATOM 913  C CG  . PRO A 1 343 ? 165.619 132.512 173.003 1.00 6.33  ? 343 PRO A CG  1 
ATOM 914  C CD  . PRO A 1 343 ? 164.198 132.092 173.057 1.00 4.21  ? 343 PRO A CD  1 
ATOM 915  N N   . THR A 1 344 ? 164.384 136.810 172.366 1.00 4.39  ? 344 THR A N   1 
ATOM 916  C CA  . THR A 1 344 ? 164.407 137.971 171.483 1.00 6.99  ? 344 THR A CA  1 
ATOM 917  C C   . THR A 1 344 ? 165.669 138.047 170.633 1.00 7.99  ? 344 THR A C   1 
ATOM 918  O O   . THR A 1 344 ? 165.702 138.833 169.681 1.00 11.08 ? 344 THR A O   1 
ATOM 919  C CB  . THR A 1 344 ? 164.269 139.262 172.293 1.00 6.32  ? 344 THR A CB  1 
ATOM 920  O OG1 . THR A 1 344 ? 165.329 139.344 173.254 1.00 5.98  ? 344 THR A OG1 1 
ATOM 921  C CG2 . THR A 1 344 ? 162.929 139.304 173.013 1.00 6.98  ? 344 THR A CG2 1 
ATOM 922  N N   . TYR A 1 345 ? 166.695 137.257 170.944 1.00 9.41  ? 345 TYR A N   1 
ATOM 923  C CA  . TYR A 1 345 ? 167.951 137.275 170.208 1.00 7.82  ? 345 TYR A CA  1 
ATOM 924  C C   . TYR A 1 345 ? 167.912 136.416 168.947 1.00 7.75  ? 345 TYR A C   1 
ATOM 925  O O   . TYR A 1 345 ? 168.968 136.122 168.375 1.00 14.63 ? 345 TYR A O   1 
ATOM 926  C CB  . TYR A 1 345 ? 169.104 136.860 171.135 1.00 8.47  ? 345 TYR A CB  1 
ATOM 927  C CG  . TYR A 1 345 ? 169.082 135.436 171.689 1.00 6.41  ? 345 TYR A CG  1 
ATOM 928  C CD1 . TYR A 1 345 ? 168.947 134.327 170.862 1.00 8.75  ? 345 TYR A CD1 1 
ATOM 929  C CD2 . TYR A 1 345 ? 169.207 135.212 173.054 1.00 8.39  ? 345 TYR A CD2 1 
ATOM 930  C CE1 . TYR A 1 345 ? 168.932 133.047 171.374 1.00 7.91  ? 345 TYR A CE1 1 
ATOM 931  C CE2 . TYR A 1 345 ? 169.195 133.932 173.576 1.00 8.36  ? 345 TYR A CE2 1 
ATOM 932  C CZ  . TYR A 1 345 ? 169.057 132.854 172.731 1.00 9.81  ? 345 TYR A CZ  1 
ATOM 933  O OH  . TYR A 1 345 ? 169.043 131.578 173.245 1.00 13.02 ? 345 TYR A OH  1 
ATOM 934  N N   . VAL A 1 346 ? 166.724 136.020 168.500 1.00 9.26  ? 346 VAL A N   1 
ATOM 935  C CA  . VAL A 1 346 ? 166.581 135.148 167.340 1.00 4.73  ? 346 VAL A CA  1 
ATOM 936  C C   . VAL A 1 346 ? 165.950 135.941 166.203 1.00 3.93  ? 346 VAL A C   1 
ATOM 937  O O   . VAL A 1 346 ? 166.204 135.670 165.024 1.00 8.24  ? 346 VAL A O   1 
ATOM 938  C CB  . VAL A 1 346 ? 165.750 133.898 167.697 1.00 5.46  ? 346 VAL A CB  1 
ATOM 939  C CG1 . VAL A 1 346 ? 165.233 133.195 166.449 1.00 4.07  ? 346 VAL A CG1 1 
ATOM 940  C CG2 . VAL A 1 346 ? 166.573 132.943 168.545 1.00 6.79  ? 346 VAL A CG2 1 
ATOM 941  N N   . TYR A 1 347 ? 165.144 136.942 166.548 1.00 4.86  ? 347 TYR A N   1 
ATOM 942  C CA  . TYR A 1 347 ? 164.418 137.712 165.542 1.00 4.92  ? 347 TYR A CA  1 
ATOM 943  C C   . TYR A 1 347 ? 165.349 138.472 164.598 1.00 3.52  ? 347 TYR A C   1 
ATOM 944  O O   . TYR A 1 347 ? 165.134 138.423 163.381 1.00 6.67  ? 347 TYR A O   1 
ATOM 945  C CB  . TYR A 1 347 ? 163.409 138.651 166.212 1.00 3.29  ? 347 TYR A CB  1 
ATOM 946  C CG  . TYR A 1 347 ? 162.301 137.894 166.903 1.00 5.53  ? 347 TYR A CG  1 
ATOM 947  C CD1 . TYR A 1 347 ? 162.500 137.306 168.144 1.00 8.94  ? 347 TYR A CD1 1 
ATOM 948  C CD2 . TYR A 1 347 ? 161.074 137.710 166.282 1.00 8.04  ? 347 TYR A CD2 1 
ATOM 949  C CE1 . TYR A 1 347 ? 161.495 136.596 168.767 1.00 8.98  ? 347 TYR A CE1 1 
ATOM 950  C CE2 . TYR A 1 347 ? 160.065 136.999 166.895 1.00 6.27  ? 347 TYR A CE2 1 
ATOM 951  C CZ  . TYR A 1 347 ? 160.281 136.443 168.136 1.00 5.25  ? 347 TYR A CZ  1 
ATOM 952  O OH  . TYR A 1 347 ? 159.278 135.731 168.750 1.00 10.15 ? 347 TYR A OH  1 
ATOM 953  N N   . PRO A 1 348 ? 166.375 139.191 165.081 1.00 5.98  ? 348 PRO A N   1 
ATOM 954  C CA  . PRO A 1 348 ? 167.383 139.694 164.128 1.00 3.28  ? 348 PRO A CA  1 
ATOM 955  C C   . PRO A 1 348 ? 168.089 138.570 163.392 1.00 6.56  ? 348 PRO A C   1 
ATOM 956  O O   . PRO A 1 348 ? 168.371 138.685 162.190 1.00 10.11 ? 348 PRO A O   1 
ATOM 957  C CB  . PRO A 1 348 ? 168.354 140.493 165.011 1.00 4.94  ? 348 PRO A CB  1 
ATOM 958  C CG  . PRO A 1 348 ? 168.040 140.126 166.408 1.00 0.93  ? 348 PRO A CG  1 
ATOM 959  C CD  . PRO A 1 348 ? 166.629 139.664 166.453 1.00 6.75  ? 348 PRO A CD  1 
ATOM 960  N N   . LEU A 1 349 ? 168.365 137.468 164.095 1.00 5.58  ? 349 LEU A N   1 
ATOM 961  C CA  . LEU A 1 349 ? 168.977 136.310 163.455 1.00 3.02  ? 349 LEU A CA  1 
ATOM 962  C C   . LEU A 1 349 ? 168.064 135.734 162.385 1.00 4.89  ? 349 LEU A C   1 
ATOM 963  O O   . LEU A 1 349 ? 168.522 135.397 161.290 1.00 7.36  ? 349 LEU A O   1 
ATOM 964  C CB  . LEU A 1 349 ? 169.314 135.250 164.504 1.00 3.39  ? 349 LEU A CB  1 
ATOM 965  C CG  . LEU A 1 349 ? 170.412 134.237 164.175 1.00 5.15  ? 349 LEU A CG  1 
ATOM 966  C CD1 . LEU A 1 349 ? 171.435 134.828 163.217 1.00 5.93  ? 349 LEU A CD1 1 
ATOM 967  C CD2 . LEU A 1 349 ? 171.084 133.757 165.454 1.00 4.54  ? 349 LEU A CD2 1 
ATOM 968  N N   . ALA A 1 350 ? 166.767 135.623 162.679 1.00 0.52  ? 350 ALA A N   1 
ATOM 969  C CA  . ALA A 1 350 ? 165.824 135.123 161.684 1.00 0.70  ? 350 ALA A CA  1 
ATOM 970  C C   . ALA A 1 350 ? 165.729 136.065 160.491 1.00 2.35  ? 350 ALA A C   1 
ATOM 971  O O   . ALA A 1 350 ? 165.672 135.616 159.342 1.00 1.95  ? 350 ALA A O   1 
ATOM 972  C CB  . ALA A 1 350 ? 164.450 134.916 162.319 1.00 2.78  ? 350 ALA A CB  1 
ATOM 973  N N   . LEU A 1 351 ? 165.717 137.376 160.744 1.00 3.27  ? 351 LEU A N   1 
ATOM 974  C CA  . LEU A 1 351 ? 165.652 138.346 159.655 1.00 3.72  ? 351 LEU A CA  1 
ATOM 975  C C   . LEU A 1 351 ? 166.851 138.212 158.723 1.00 1.38  ? 351 LEU A C   1 
ATOM 976  O O   . LEU A 1 351 ? 166.696 138.112 157.499 1.00 0.00  ? 351 LEU A O   1 
ATOM 977  C CB  . LEU A 1 351 ? 165.568 139.762 160.223 1.00 5.49  ? 351 LEU A CB  1 
ATOM 978  C CG  . LEU A 1 351 ? 165.895 140.900 159.254 1.00 2.28  ? 351 LEU A CG  1 
ATOM 979  C CD1 . LEU A 1 351 ? 164.730 141.161 158.312 1.00 0.71  ? 351 LEU A CD1 1 
ATOM 980  C CD2 . LEU A 1 351 ? 166.275 142.165 160.009 1.00 0.40  ? 351 LEU A CD2 1 
ATOM 981  N N   . TYR A 1 352 ? 168.060 138.188 159.288 1.00 0.63  ? 352 TYR A N   1 
ATOM 982  C CA  . TYR A 1 352 ? 169.245 138.114 158.440 1.00 1.17  ? 352 TYR A CA  1 
ATOM 983  C C   . TYR A 1 352 ? 169.399 136.739 157.800 1.00 3.13  ? 352 TYR A C   1 
ATOM 984  O O   . TYR A 1 352 ? 169.883 136.639 156.666 1.00 2.95  ? 352 TYR A O   1 
ATOM 985  C CB  . TYR A 1 352 ? 170.488 138.500 159.239 1.00 0.85  ? 352 TYR A CB  1 
ATOM 986  C CG  . TYR A 1 352 ? 170.509 139.968 159.601 1.00 2.30  ? 352 TYR A CG  1 
ATOM 987  C CD1 . TYR A 1 352 ? 170.326 140.941 158.628 1.00 1.29  ? 352 TYR A CD1 1 
ATOM 988  C CD2 . TYR A 1 352 ? 170.691 140.382 160.915 1.00 2.06  ? 352 TYR A CD2 1 
ATOM 989  C CE1 . TYR A 1 352 ? 170.334 142.284 158.949 1.00 3.58  ? 352 TYR A CE1 1 
ATOM 990  C CE2 . TYR A 1 352 ? 170.701 141.723 161.245 1.00 0.78  ? 352 TYR A CE2 1 
ATOM 991  C CZ  . TYR A 1 352 ? 170.523 142.670 160.257 1.00 4.12  ? 352 TYR A CZ  1 
ATOM 992  O OH  . TYR A 1 352 ? 170.532 144.009 160.576 1.00 4.43  ? 352 TYR A OH  1 
ATOM 993  N N   . GLY A 1 353 ? 168.972 135.676 158.485 1.00 1.27  ? 353 GLY A N   1 
ATOM 994  C CA  . GLY A 1 353 ? 168.997 134.361 157.873 1.00 1.48  ? 353 GLY A CA  1 
ATOM 995  C C   . GLY A 1 353 ? 168.056 134.256 156.691 1.00 2.04  ? 353 GLY A C   1 
ATOM 996  O O   . GLY A 1 353 ? 168.409 133.690 155.655 1.00 7.90  ? 353 GLY A O   1 
ATOM 997  N N   . PHE A 1 354 ? 166.847 134.806 156.825 1.00 3.40  ? 354 PHE A N   1 
ATOM 998  C CA  . PHE A 1 354 ? 165.929 134.824 155.695 1.00 0.91  ? 354 PHE A CA  1 
ATOM 999  C C   . PHE A 1 354 ? 166.472 135.686 154.567 1.00 1.95  ? 354 PHE A C   1 
ATOM 1000 O O   . PHE A 1 354 ? 166.284 135.365 153.393 1.00 2.57  ? 354 PHE A O   1 
ATOM 1001 C CB  . PHE A 1 354 ? 164.548 135.319 156.118 1.00 3.31  ? 354 PHE A CB  1 
ATOM 1002 C CG  . PHE A 1 354 ? 163.562 135.372 154.986 1.00 4.39  ? 354 PHE A CG  1 
ATOM 1003 C CD1 . PHE A 1 354 ? 162.826 134.252 154.640 1.00 0.42  ? 354 PHE A CD1 1 
ATOM 1004 C CD2 . PHE A 1 354 ? 163.387 136.534 154.252 1.00 3.83  ? 354 PHE A CD2 1 
ATOM 1005 C CE1 . PHE A 1 354 ? 161.926 134.293 153.594 1.00 4.23  ? 354 PHE A CE1 1 
ATOM 1006 C CE2 . PHE A 1 354 ? 162.488 136.580 153.202 1.00 4.53  ? 354 PHE A CE2 1 
ATOM 1007 C CZ  . PHE A 1 354 ? 161.757 135.459 152.875 1.00 3.98  ? 354 PHE A CZ  1 
ATOM 1008 N N   . MET A 1 355 ? 167.132 136.794 154.902 1.00 6.35  ? 355 MET A N   1 
ATOM 1009 C CA  . MET A 1 355 ? 167.726 137.637 153.869 1.00 1.86  ? 355 MET A CA  1 
ATOM 1010 C C   . MET A 1 355 ? 168.793 136.873 153.088 1.00 2.73  ? 355 MET A C   1 
ATOM 1011 O O   . MET A 1 355 ? 168.810 136.885 151.849 1.00 1.91  ? 355 MET A O   1 
ATOM 1012 C CB  . MET A 1 355 ? 168.300 138.893 154.521 1.00 6.11  ? 355 MET A CB  1 
ATOM 1013 C CG  . MET A 1 355 ? 167.399 140.109 154.404 1.00 4.94  ? 355 MET A CG  1 
ATOM 1014 S SD  . MET A 1 355 ? 167.825 141.399 155.589 1.00 11.23 ? 355 MET A SD  1 
ATOM 1015 C CE  . MET A 1 355 ? 169.204 142.177 154.770 1.00 6.93  ? 355 MET A CE  1 
ATOM 1016 N N   . VAL A 1 356 ? 169.665 136.159 153.805 1.00 5.12  ? 356 VAL A N   1 
ATOM 1017 C CA  . VAL A 1 356 ? 170.708 135.366 153.158 1.00 6.33  ? 356 VAL A CA  1 
ATOM 1018 C C   . VAL A 1 356 ? 170.095 134.257 152.309 1.00 4.34  ? 356 VAL A C   1 
ATOM 1019 O O   . VAL A 1 356 ? 170.515 134.024 151.169 1.00 4.17  ? 356 VAL A O   1 
ATOM 1020 C CB  . VAL A 1 356 ? 171.678 134.802 154.215 1.00 1.84  ? 356 VAL A CB  1 
ATOM 1021 C CG1 . VAL A 1 356 ? 172.409 133.579 153.681 1.00 5.09  ? 356 VAL A CG1 1 
ATOM 1022 C CG2 . VAL A 1 356 ? 172.666 135.871 154.655 1.00 0.39  ? 356 VAL A CG2 1 
ATOM 1023 N N   . PHE A 1 357 ? 169.094 133.555 152.847 1.00 4.43  ? 357 PHE A N   1 
ATOM 1024 C CA  . PHE A 1 357 ? 168.482 132.452 152.113 1.00 4.86  ? 357 PHE A CA  1 
ATOM 1025 C C   . PHE A 1 357 ? 167.735 132.948 150.881 1.00 4.67  ? 357 PHE A C   1 
ATOM 1026 O O   . PHE A 1 357 ? 167.788 132.315 149.822 1.00 4.98  ? 357 PHE A O   1 
ATOM 1027 C CB  . PHE A 1 357 ? 167.550 131.663 153.029 1.00 3.92  ? 357 PHE A CB  1 
ATOM 1028 C CG  . PHE A 1 357 ? 168.219 130.514 153.726 1.00 5.16  ? 357 PHE A CG  1 
ATOM 1029 C CD1 . PHE A 1 357 ? 169.524 130.624 154.175 1.00 4.84  ? 357 PHE A CD1 1 
ATOM 1030 C CD2 . PHE A 1 357 ? 167.546 129.322 153.926 1.00 7.89  ? 357 PHE A CD2 1 
ATOM 1031 C CE1 . PHE A 1 357 ? 170.145 129.568 154.815 1.00 7.78  ? 357 PHE A CE1 1 
ATOM 1032 C CE2 . PHE A 1 357 ? 168.162 128.262 154.565 1.00 6.44  ? 357 PHE A CE2 1 
ATOM 1033 C CZ  . PHE A 1 357 ? 169.463 128.385 155.009 1.00 9.03  ? 357 PHE A CZ  1 
ATOM 1034 N N   . PHE A 1 358 ? 167.039 134.079 151.001 1.00 4.05  ? 358 PHE A N   1 
ATOM 1035 C CA  . PHE A 1 358 ? 166.370 134.679 149.855 1.00 3.79  ? 358 PHE A CA  1 
ATOM 1036 C C   . PHE A 1 358 ? 167.377 135.054 148.781 1.00 4.50  ? 358 PHE A C   1 
ATOM 1037 O O   . PHE A 1 358 ? 167.124 134.860 147.588 1.00 4.84  ? 358 PHE A O   1 
ATOM 1038 C CB  . PHE A 1 358 ? 165.571 135.905 150.308 1.00 2.33  ? 358 PHE A CB  1 
ATOM 1039 C CG  . PHE A 1 358 ? 164.968 136.698 149.181 1.00 4.19  ? 358 PHE A CG  1 
ATOM 1040 C CD1 . PHE A 1 358 ? 163.710 136.385 148.695 1.00 7.27  ? 358 PHE A CD1 1 
ATOM 1041 C CD2 . PHE A 1 358 ? 165.651 137.764 148.617 1.00 3.40  ? 358 PHE A CD2 1 
ATOM 1042 C CE1 . PHE A 1 358 ? 163.150 137.112 147.662 1.00 4.27  ? 358 PHE A CE1 1 
ATOM 1043 C CE2 . PHE A 1 358 ? 165.097 138.491 147.583 1.00 3.46  ? 358 PHE A CE2 1 
ATOM 1044 C CZ  . PHE A 1 358 ? 163.845 138.164 147.106 1.00 6.26  ? 358 PHE A CZ  1 
ATOM 1045 N N   . LEU A 1 359 ? 168.529 135.591 149.187 1.00 1.44  ? 359 LEU A N   1 
ATOM 1046 C CA  . LEU A 1 359 ? 169.570 135.909 148.218 1.00 3.26  ? 359 LEU A CA  1 
ATOM 1047 C C   . LEU A 1 359 ? 170.163 134.651 147.588 1.00 2.97  ? 359 LEU A C   1 
ATOM 1048 O O   . LEU A 1 359 ? 170.560 134.676 146.418 1.00 8.02  ? 359 LEU A O   1 
ATOM 1049 C CB  . LEU A 1 359 ? 170.659 136.745 148.896 1.00 3.53  ? 359 LEU A CB  1 
ATOM 1050 C CG  . LEU A 1 359 ? 171.752 137.457 148.088 1.00 6.39  ? 359 LEU A CG  1 
ATOM 1051 C CD1 . LEU A 1 359 ? 173.057 136.684 148.150 1.00 2.99  ? 359 LEU A CD1 1 
ATOM 1052 C CD2 . LEU A 1 359 ? 171.340 137.724 146.642 1.00 1.08  ? 359 LEU A CD2 1 
ATOM 1053 N N   . ILE A 1 360 ? 170.209 133.541 148.325 1.00 3.64  ? 360 ILE A N   1 
ATOM 1054 C CA  . ILE A 1 360 ? 171.030 132.395 147.941 1.00 3.64  ? 360 ILE A CA  1 
ATOM 1055 C C   . ILE A 1 360 ? 170.226 131.158 147.556 1.00 5.98  ? 360 ILE A C   1 
ATOM 1056 O O   . ILE A 1 360 ? 170.827 130.184 147.072 1.00 5.90  ? 360 ILE A O   1 
ATOM 1057 C CB  . ILE A 1 360 ? 172.037 132.036 149.056 1.00 5.93  ? 360 ILE A CB  1 
ATOM 1058 C CG1 . ILE A 1 360 ? 173.347 131.519 148.461 1.00 7.56  ? 360 ILE A CG1 1 
ATOM 1059 C CG2 . ILE A 1 360 ? 171.437 131.027 150.031 1.00 5.23  ? 360 ILE A CG2 1 
ATOM 1060 C CD1 . ILE A 1 360 ? 174.543 131.715 149.364 1.00 6.10  ? 360 ILE A CD1 1 
ATOM 1061 N N   . ASN A 1 361 ? 168.907 131.154 147.736 1.00 5.58  ? 361 ASN A N   1 
ATOM 1062 C CA  . ASN A 1 361 ? 168.143 129.926 147.538 1.00 4.18  ? 361 ASN A CA  1 
ATOM 1063 C C   . ASN A 1 361 ? 168.238 129.466 146.085 1.00 7.51  ? 361 ASN A C   1 
ATOM 1064 O O   . ASN A 1 361 ? 168.066 130.280 145.166 1.00 10.91 ? 361 ASN A O   1 
ATOM 1065 C CB  . ASN A 1 361 ? 166.678 130.112 147.934 1.00 7.04  ? 361 ASN A CB  1 
ATOM 1066 C CG  . ASN A 1 361 ? 165.968 131.141 147.085 1.00 7.74  ? 361 ASN A CG  1 
ATOM 1067 O OD1 . ASN A 1 361 ? 166.457 132.254 146.906 1.00 11.60 ? 361 ASN A OD1 1 
ATOM 1068 N ND2 . ASN A 1 361 ? 164.810 130.772 146.550 1.00 5.03  ? 361 ASN A ND2 1 
ATOM 1069 N N   . PRO A 1 362 ? 168.515 128.182 145.833 1.00 6.57  ? 362 PRO A N   1 
ATOM 1070 C CA  . PRO A 1 362 ? 168.665 127.712 144.449 1.00 5.74  ? 362 PRO A CA  1 
ATOM 1071 C C   . PRO A 1 362 ? 167.351 127.552 143.707 1.00 4.41  ? 362 PRO A C   1 
ATOM 1072 O O   . PRO A 1 362 ? 167.374 127.330 142.489 1.00 10.29 ? 362 PRO A O   1 
ATOM 1073 C CB  . PRO A 1 362 ? 169.372 126.353 144.609 1.00 5.17  ? 362 PRO A CB  1 
ATOM 1074 C CG  . PRO A 1 362 ? 169.502 126.106 146.095 1.00 5.96  ? 362 PRO A CG  1 
ATOM 1075 C CD  . PRO A 1 362 ? 168.640 127.090 146.809 1.00 5.77  ? 362 PRO A CD  1 
ATOM 1076 N N   . THR A 1 363 ? 166.217 127.654 144.395 1.00 9.58  ? 363 THR A N   1 
ATOM 1077 C CA  . THR A 1 363 ? 164.925 127.544 143.734 1.00 5.45  ? 363 THR A CA  1 
ATOM 1078 C C   . THR A 1 363 ? 164.728 128.695 142.753 1.00 6.88  ? 363 THR A C   1 
ATOM 1079 O O   . THR A 1 363 ? 165.203 129.812 142.972 1.00 11.90 ? 363 THR A O   1 
ATOM 1080 C CB  . THR A 1 363 ? 163.801 127.530 144.769 1.00 8.00  ? 363 THR A CB  1 
ATOM 1081 O OG1 . THR A 1 363 ? 163.804 128.764 145.497 1.00 10.68 ? 363 THR A OG1 1 
ATOM 1082 C CG2 . THR A 1 363 ? 163.992 126.373 145.741 1.00 5.78  ? 363 THR A CG2 1 
ATOM 1083 N N   . LYS A 1 364 ? 164.021 128.410 141.666 1.00 5.43  ? 364 LYS A N   1 
ATOM 1084 C CA  . LYS A 1 364 ? 163.847 129.357 140.567 1.00 2.51  ? 364 LYS A CA  1 
ATOM 1085 C C   . LYS A 1 364 ? 162.555 130.152 140.750 1.00 7.06  ? 364 LYS A C   1 
ATOM 1086 O O   . LYS A 1 364 ? 161.665 130.143 139.900 1.00 9.04  ? 364 LYS A O   1 
ATOM 1087 C CB  . LYS A 1 364 ? 163.844 128.606 139.239 1.00 3.78  ? 364 LYS A CB  1 
ATOM 1088 C CG  . LYS A 1 364 ? 165.217 128.199 138.734 1.00 5.51  ? 364 LYS A CG  1 
ATOM 1089 C CD  . LYS A 1 364 ? 165.290 128.250 137.219 1.00 7.44  ? 364 LYS A CD  1 
ATOM 1090 C CE  . LYS A 1 364 ? 166.731 128.249 136.742 1.00 5.69  ? 364 LYS A CE  1 
ATOM 1091 N NZ  . LYS A 1 364 ? 167.211 126.867 136.457 1.00 8.71  ? 364 LYS A NZ  1 
ATOM 1092 N N   . THR A 1 365 ? 162.455 130.860 141.877 1.00 7.57  ? 365 THR A N   1 
ATOM 1093 C CA  . THR A 1 365 ? 161.167 131.394 142.311 1.00 6.26  ? 365 THR A CA  1 
ATOM 1094 C C   . THR A 1 365 ? 161.110 132.918 142.325 1.00 7.69  ? 365 THR A C   1 
ATOM 1095 O O   . THR A 1 365 ? 160.233 133.493 141.672 1.00 10.92 ? 365 THR A O   1 
ATOM 1096 C CB  . THR A 1 365 ? 160.822 130.827 143.693 1.00 7.57  ? 365 THR A CB  1 
ATOM 1097 O OG1 . THR A 1 365 ? 161.383 129.515 143.823 1.00 10.73 ? 365 THR A OG1 1 
ATOM 1098 C CG2 . THR A 1 365 ? 159.315 130.723 143.854 1.00 9.14  ? 365 THR A CG2 1 
ATOM 1099 N N   . PHE A 1 366 ? 162.002 133.601 143.046 1.00 7.98  ? 366 PHE A N   1 
ATOM 1100 C CA  . PHE A 1 366 ? 161.888 135.044 143.261 1.00 6.06  ? 366 PHE A CA  1 
ATOM 1101 C C   . PHE A 1 366 ? 163.104 135.749 142.671 1.00 4.90  ? 366 PHE A C   1 
ATOM 1102 O O   . PHE A 1 366 ? 164.190 135.710 143.259 1.00 3.12  ? 366 PHE A O   1 
ATOM 1103 C CB  . PHE A 1 366 ? 161.754 135.373 144.750 1.00 4.55  ? 366 PHE A CB  1 
ATOM 1104 C CG  . PHE A 1 366 ? 160.550 134.761 145.408 1.00 2.91  ? 366 PHE A CG  1 
ATOM 1105 C CD1 . PHE A 1 366 ? 160.602 133.477 145.922 1.00 4.89  ? 366 PHE A CD1 1 
ATOM 1106 C CD2 . PHE A 1 366 ? 159.366 135.470 145.516 1.00 6.01  ? 366 PHE A CD2 1 
ATOM 1107 C CE1 . PHE A 1 366 ? 159.498 132.913 146.531 1.00 7.50  ? 366 PHE A CE1 1 
ATOM 1108 C CE2 . PHE A 1 366 ? 158.258 134.910 146.122 1.00 3.25  ? 366 PHE A CE2 1 
ATOM 1109 C CZ  . PHE A 1 366 ? 158.324 133.629 146.629 1.00 2.89  ? 366 PHE A CZ  1 
ATOM 1110 N N   . TYR A 1 367 ? 162.910 136.413 141.532 1.00 7.08  ? 367 TYR A N   1 
ATOM 1111 C CA  . TYR A 1 367 ? 163.963 137.157 140.835 1.00 5.51  ? 367 TYR A CA  1 
ATOM 1112 C C   . TYR A 1 367 ? 165.237 136.326 140.703 1.00 3.47  ? 367 TYR A C   1 
ATOM 1113 O O   . TYR A 1 367 ? 166.347 136.799 140.955 1.00 6.84  ? 367 TYR A O   1 
ATOM 1114 C CB  . TYR A 1 367 ? 164.267 138.486 141.530 1.00 3.59  ? 367 TYR A CB  1 
ATOM 1115 C CG  . TYR A 1 367 ? 163.071 139.227 142.087 1.00 5.58  ? 367 TYR A CG  1 
ATOM 1116 C CD1 . TYR A 1 367 ? 162.640 139.012 143.389 1.00 2.84  ? 367 TYR A CD1 1 
ATOM 1117 C CD2 . TYR A 1 367 ? 162.391 140.161 141.319 1.00 6.39  ? 367 TYR A CD2 1 
ATOM 1118 C CE1 . TYR A 1 367 ? 161.556 139.693 143.903 1.00 0.57  ? 367 TYR A CE1 1 
ATOM 1119 C CE2 . TYR A 1 367 ? 161.304 140.848 141.826 1.00 4.10  ? 367 TYR A CE2 1 
ATOM 1120 C CZ  . TYR A 1 367 ? 160.892 140.609 143.117 1.00 7.89  ? 367 TYR A CZ  1 
ATOM 1121 O OH  . TYR A 1 367 ? 159.813 141.292 143.629 1.00 15.25 ? 367 TYR A OH  1 
ATOM 1122 N N   . TYR A 1 368 ? 165.069 135.064 140.302 1.00 0.00  ? 368 TYR A N   1 
ATOM 1123 C CA  . TYR A 1 368 ? 166.191 134.132 140.343 1.00 0.86  ? 368 TYR A CA  1 
ATOM 1124 C C   . TYR A 1 368 ? 167.299 134.520 139.369 1.00 1.72  ? 368 TYR A C   1 
ATOM 1125 O O   . TYR A 1 368 ? 168.480 134.332 139.680 1.00 7.92  ? 368 TYR A O   1 
ATOM 1126 C CB  . TYR A 1 368 ? 165.696 132.701 140.095 1.00 1.91  ? 368 TYR A CB  1 
ATOM 1127 C CG  . TYR A 1 368 ? 165.062 132.438 138.747 1.00 3.29  ? 368 TYR A CG  1 
ATOM 1128 C CD1 . TYR A 1 368 ? 165.838 132.200 137.621 1.00 4.47  ? 368 TYR A CD1 1 
ATOM 1129 C CD2 . TYR A 1 368 ? 163.684 132.356 138.617 1.00 4.28  ? 368 TYR A CD2 1 
ATOM 1130 C CE1 . TYR A 1 368 ? 165.256 131.936 136.396 1.00 4.49  ? 368 TYR A CE1 1 
ATOM 1131 C CE2 . TYR A 1 368 ? 163.093 132.096 137.397 1.00 4.94  ? 368 TYR A CE2 1 
ATOM 1132 C CZ  . TYR A 1 368 ? 163.884 131.884 136.291 1.00 6.22  ? 368 TYR A CZ  1 
ATOM 1133 O OH  . TYR A 1 368 ? 163.299 131.622 135.074 1.00 8.70  ? 368 TYR A OH  1 
ATOM 1134 N N   . LYS A 1 369 ? 166.952 135.068 138.203 1.00 0.15  ? 369 LYS A N   1 
ATOM 1135 C CA  . LYS A 1 369 ? 167.978 135.528 137.271 1.00 2.43  ? 369 LYS A CA  1 
ATOM 1136 C C   . LYS A 1 369 ? 168.811 136.649 137.879 1.00 6.49  ? 369 LYS A C   1 
ATOM 1137 O O   . LYS A 1 369 ? 170.049 136.608 137.849 1.00 9.72  ? 369 LYS A O   1 
ATOM 1138 C CB  . LYS A 1 369 ? 167.331 135.984 135.961 1.00 3.26  ? 369 LYS A CB  1 
ATOM 1139 C CG  . LYS A 1 369 ? 166.616 134.911 135.118 1.00 2.56  ? 369 LYS A CG  1 
ATOM 1140 C CD  . LYS A 1 369 ? 167.535 133.929 134.352 1.00 6.47  ? 369 LYS A CD  1 
ATOM 1141 C CE  . LYS A 1 369 ? 168.408 133.016 135.205 1.00 3.79  ? 369 LYS A CE  1 
ATOM 1142 N NZ  . LYS A 1 369 ? 168.931 131.862 134.425 1.00 6.85  ? 369 LYS A NZ  1 
ATOM 1143 N N   . SER A 1 370 ? 168.143 137.655 138.449 1.00 0.05  ? 370 SER A N   1 
ATOM 1144 C CA  . SER A 1 370 ? 168.855 138.757 139.085 1.00 4.00  ? 370 SER A CA  1 
ATOM 1145 C C   . SER A 1 370 ? 169.686 138.266 140.261 1.00 2.39  ? 370 SER A C   1 
ATOM 1146 O O   . SER A 1 370 ? 170.826 138.704 140.451 1.00 4.37  ? 370 SER A O   1 
ATOM 1147 C CB  . SER A 1 370 ? 167.865 139.830 139.540 1.00 2.29  ? 370 SER A CB  1 
ATOM 1148 O OG  . SER A 1 370 ? 167.235 140.446 138.432 1.00 8.47  ? 370 SER A OG  1 
ATOM 1149 N N   . ARG A 1 371 ? 169.132 137.352 141.059 1.00 1.81  ? 371 ARG A N   1 
ATOM 1150 C CA  . ARG A 1 371 ? 169.853 136.840 142.220 1.00 3.14  ? 371 ARG A CA  1 
ATOM 1151 C C   . ARG A 1 371 ? 171.108 136.079 141.809 1.00 0.68  ? 371 ARG A C   1 
ATOM 1152 O O   . ARG A 1 371 ? 172.168 136.247 142.418 1.00 0.00  ? 371 ARG A O   1 
ATOM 1153 C CB  . ARG A 1 371 ? 168.932 135.953 143.053 1.00 1.51  ? 371 ARG A CB  1 
ATOM 1154 C CG  . ARG A 1 371 ? 167.816 136.711 143.748 1.00 3.10  ? 371 ARG A CG  1 
ATOM 1155 C CD  . ARG A 1 371 ? 167.027 135.815 144.681 1.00 3.05  ? 371 ARG A CD  1 
ATOM 1156 N NE  . ARG A 1 371 ? 166.401 134.691 143.991 1.00 2.65  ? 371 ARG A NE  1 
ATOM 1157 C CZ  . ARG A 1 371 ? 166.847 133.443 144.030 1.00 0.88  ? 371 ARG A CZ  1 
ATOM 1158 N NH1 . ARG A 1 371 ? 167.939 133.120 144.702 1.00 2.72  ? 371 ARG A NH1 1 
ATOM 1159 N NH2 . ARG A 1 371 ? 166.180 132.496 143.378 1.00 0.00  ? 371 ARG A NH2 1 
ATOM 1160 N N   . PHE A 1 372 ? 171.011 135.239 140.775 1.00 1.89  ? 372 PHE A N   1 
ATOM 1161 C CA  . PHE A 1 372 ? 172.180 134.480 140.334 1.00 2.63  ? 372 PHE A CA  1 
ATOM 1162 C C   . PHE A 1 372 ? 173.228 135.393 139.706 1.00 3.30  ? 372 PHE A C   1 
ATOM 1163 O O   . PHE A 1 372 ? 174.436 135.200 139.912 1.00 0.97  ? 372 PHE A O   1 
ATOM 1164 C CB  . PHE A 1 372 ? 171.762 133.379 139.357 1.00 4.61  ? 372 PHE A CB  1 
ATOM 1165 C CG  . PHE A 1 372 ? 170.764 132.399 139.922 1.00 3.82  ? 372 PHE A CG  1 
ATOM 1166 C CD1 . PHE A 1 372 ? 170.566 132.288 141.291 1.00 3.75  ? 372 PHE A CD1 1 
ATOM 1167 C CD2 . PHE A 1 372 ? 170.023 131.586 139.078 1.00 6.12  ? 372 PHE A CD2 1 
ATOM 1168 C CE1 . PHE A 1 372 ? 169.651 131.388 141.805 1.00 2.76  ? 372 PHE A CE1 1 
ATOM 1169 C CE2 . PHE A 1 372 ? 169.105 130.683 139.588 1.00 7.76  ? 372 PHE A CE2 1 
ATOM 1170 C CZ  . PHE A 1 372 ? 168.919 130.585 140.954 1.00 1.54  ? 372 PHE A CZ  1 
ATOM 1171 N N   . TRP A 1 373 ? 172.788 136.400 138.944 1.00 0.00  ? 373 TRP A N   1 
ATOM 1172 C CA  . TRP A 1 373 ? 173.729 137.377 138.409 1.00 0.39  ? 373 TRP A CA  1 
ATOM 1173 C C   . TRP A 1 373 ? 174.452 138.111 139.533 1.00 1.36  ? 373 TRP A C   1 
ATOM 1174 O O   . TRP A 1 373 ? 175.674 138.303 139.477 1.00 2.00  ? 373 TRP A O   1 
ATOM 1175 C CB  . TRP A 1 373 ? 172.992 138.363 137.499 1.00 1.26  ? 373 TRP A CB  1 
ATOM 1176 C CG  . TRP A 1 373 ? 173.847 139.472 136.968 1.00 0.60  ? 373 TRP A CG  1 
ATOM 1177 C CD1 . TRP A 1 373 ? 174.594 139.455 135.828 1.00 2.48  ? 373 TRP A CD1 1 
ATOM 1178 C CD2 . TRP A 1 373 ? 174.035 140.769 137.550 1.00 0.51  ? 373 TRP A CD2 1 
ATOM 1179 N NE1 . TRP A 1 373 ? 175.239 140.655 135.665 1.00 3.85  ? 373 TRP A NE1 1 
ATOM 1180 C CE2 . TRP A 1 373 ? 174.912 141.479 136.708 1.00 0.08  ? 373 TRP A CE2 1 
ATOM 1181 C CE3 . TRP A 1 373 ? 173.551 141.395 138.702 1.00 0.00  ? 373 TRP A CE3 1 
ATOM 1182 C CZ2 . TRP A 1 373 ? 175.315 142.785 136.981 1.00 0.90  ? 373 TRP A CZ2 1 
ATOM 1183 C CZ3 . TRP A 1 373 ? 173.950 142.690 138.970 1.00 3.07  ? 373 TRP A CZ3 1 
ATOM 1184 C CH2 . TRP A 1 373 ? 174.822 143.373 138.113 1.00 3.66  ? 373 TRP A CH2 1 
ATOM 1185 N N   . LEU A 1 374 ? 173.714 138.509 140.572 1.00 0.00  ? 374 LEU A N   1 
ATOM 1186 C CA  . LEU A 1 374 ? 174.326 139.195 141.705 1.00 0.00  ? 374 LEU A CA  1 
ATOM 1187 C C   . LEU A 1 374 ? 175.281 138.280 142.457 1.00 0.00  ? 374 LEU A C   1 
ATOM 1188 O O   . LEU A 1 374 ? 176.321 138.731 142.943 1.00 0.00  ? 374 LEU A O   1 
ATOM 1189 C CB  . LEU A 1 374 ? 173.243 139.731 142.642 1.00 0.00  ? 374 LEU A CB  1 
ATOM 1190 C CG  . LEU A 1 374 ? 173.732 140.534 143.850 1.00 0.00  ? 374 LEU A CG  1 
ATOM 1191 C CD1 . LEU A 1 374 ? 174.488 141.778 143.402 1.00 0.00  ? 374 LEU A CD1 1 
ATOM 1192 C CD2 . LEU A 1 374 ? 172.574 140.901 144.764 1.00 0.00  ? 374 LEU A CD2 1 
ATOM 1193 N N   . LEU A 1 375 ? 174.935 136.997 142.581 1.00 1.73  ? 375 LEU A N   1 
ATOM 1194 C CA  . LEU A 1 375 ? 175.814 136.047 143.252 1.00 0.37  ? 375 LEU A CA  1 
ATOM 1195 C C   . LEU A 1 375 ? 177.135 135.912 142.507 1.00 0.39  ? 375 LEU A C   1 
ATOM 1196 O O   . LEU A 1 375 ? 178.216 135.938 143.114 1.00 0.00  ? 375 LEU A O   1 
ATOM 1197 C CB  . LEU A 1 375 ? 175.117 134.692 143.367 1.00 0.00  ? 375 LEU A CB  1 
ATOM 1198 C CG  . LEU A 1 375 ? 174.139 134.514 144.529 1.00 1.44  ? 375 LEU A CG  1 
ATOM 1199 C CD1 . LEU A 1 375 ? 173.368 133.211 144.385 1.00 2.05  ? 375 LEU A CD1 1 
ATOM 1200 C CD2 . LEU A 1 375 ? 174.876 134.556 145.854 1.00 3.95  ? 375 LEU A CD2 1 
ATOM 1201 N N   . LYS A 1 376 ? 177.064 135.785 141.180 1.00 0.00  ? 376 LYS A N   1 
ATOM 1202 C CA  . LYS A 1 376 ? 178.285 135.711 140.386 1.00 0.00  ? 376 LYS A CA  1 
ATOM 1203 C C   . LYS A 1 376 ? 179.096 136.996 140.499 1.00 0.99  ? 376 LYS A C   1 
ATOM 1204 O O   . LYS A 1 376 ? 180.327 136.952 140.608 1.00 0.64  ? 376 LYS A O   1 
ATOM 1205 C CB  . LYS A 1 376 ? 177.947 135.408 138.927 1.00 0.90  ? 376 LYS A CB  1 
ATOM 1206 C CG  . LYS A 1 376 ? 177.626 133.946 138.671 1.00 1.49  ? 376 LYS A CG  1 
ATOM 1207 C CD  . LYS A 1 376 ? 177.702 133.612 137.194 1.00 3.51  ? 376 LYS A CD  1 
ATOM 1208 C CE  . LYS A 1 376 ? 176.357 133.804 136.518 1.00 2.77  ? 376 LYS A CE  1 
ATOM 1209 N NZ  . LYS A 1 376 ? 175.260 133.151 137.280 1.00 4.08  ? 376 LYS A NZ  1 
ATOM 1210 N N   . LEU A 1 377 ? 178.424 138.153 140.484 1.00 0.00  ? 377 LEU A N   1 
ATOM 1211 C CA  . LEU A 1 377 ? 179.141 139.420 140.608 1.00 0.00  ? 377 LEU A CA  1 
ATOM 1212 C C   . LEU A 1 377 ? 179.819 139.552 141.969 1.00 0.00  ? 377 LEU A C   1 
ATOM 1213 O O   . LEU A 1 377 ? 180.952 140.031 142.055 1.00 0.00  ? 377 LEU A O   1 
ATOM 1214 C CB  . LEU A 1 377 ? 178.193 140.593 140.365 1.00 0.00  ? 377 LEU A CB  1 
ATOM 1215 C CG  . LEU A 1 377 ? 178.861 141.970 140.302 1.00 0.00  ? 377 LEU A CG  1 
ATOM 1216 C CD1 . LEU A 1 377 ? 180.026 141.969 139.324 1.00 0.00  ? 377 LEU A CD1 1 
ATOM 1217 C CD2 . LEU A 1 377 ? 177.855 143.046 139.935 1.00 0.00  ? 377 LEU A CD2 1 
ATOM 1218 N N   . LEU A 1 378 ? 179.142 139.138 143.043 1.00 0.00  ? 378 LEU A N   1 
ATOM 1219 C CA  . LEU A 1 378 ? 179.746 139.200 144.371 1.00 1.88  ? 378 LEU A CA  1 
ATOM 1220 C C   . LEU A 1 378 ? 180.955 138.280 144.472 1.00 3.81  ? 378 LEU A C   1 
ATOM 1221 O O   . LEU A 1 378 ? 181.990 138.659 145.039 1.00 1.31  ? 378 LEU A O   1 
ATOM 1222 C CB  . LEU A 1 378 ? 178.711 138.839 145.437 1.00 1.07  ? 378 LEU A CB  1 
ATOM 1223 C CG  . LEU A 1 378 ? 177.618 139.866 145.723 1.00 0.82  ? 378 LEU A CG  1 
ATOM 1224 C CD1 . LEU A 1 378 ? 176.432 139.193 146.389 1.00 1.71  ? 378 LEU A CD1 1 
ATOM 1225 C CD2 . LEU A 1 378 ? 178.154 140.991 146.591 1.00 0.00  ? 378 LEU A CD2 1 
ATOM 1226 N N   . PHE A 1 379 ? 180.846 137.065 143.924 1.00 0.25  ? 379 PHE A N   1 
ATOM 1227 C CA  . PHE A 1 379 ? 181.997 136.168 143.907 1.00 0.00  ? 379 PHE A CA  1 
ATOM 1228 C C   . PHE A 1 379 ? 183.151 136.777 143.123 1.00 0.00  ? 379 PHE A C   1 
ATOM 1229 O O   . PHE A 1 379 ? 184.311 136.694 143.543 1.00 3.13  ? 379 PHE A O   1 
ATOM 1230 C CB  . PHE A 1 379 ? 181.603 134.813 143.316 1.00 0.00  ? 379 PHE A CB  1 
ATOM 1231 C CG  . PHE A 1 379 ? 182.772 133.911 143.039 1.00 0.00  ? 379 PHE A CG  1 
ATOM 1232 C CD1 . PHE A 1 379 ? 183.305 133.120 144.043 1.00 2.63  ? 379 PHE A CD1 1 
ATOM 1233 C CD2 . PHE A 1 379 ? 183.334 133.847 141.775 1.00 0.19  ? 379 PHE A CD2 1 
ATOM 1234 C CE1 . PHE A 1 379 ? 184.380 132.288 143.793 1.00 3.07  ? 379 PHE A CE1 1 
ATOM 1235 C CE2 . PHE A 1 379 ? 184.409 133.020 141.520 1.00 1.77  ? 379 PHE A CE2 1 
ATOM 1236 C CZ  . PHE A 1 379 ? 184.932 132.238 142.530 1.00 1.37  ? 379 PHE A CZ  1 
ATOM 1237 N N   . ARG A 1 380 ? 182.849 137.391 141.978 1.00 2.45  ? 380 ARG A N   1 
ATOM 1238 C CA  . ARG A 1 380 ? 183.884 138.029 141.173 1.00 1.25  ? 380 ARG A CA  1 
ATOM 1239 C C   . ARG A 1 380 ? 184.540 139.179 141.931 1.00 1.77  ? 380 ARG A C   1 
ATOM 1240 O O   . ARG A 1 380 ? 185.759 139.370 141.855 1.00 0.32  ? 380 ARG A O   1 
ATOM 1241 C CB  . ARG A 1 380 ? 183.276 138.520 139.858 1.00 1.02  ? 380 ARG A CB  1 
ATOM 1242 C CG  . ARG A 1 380 ? 183.955 137.972 138.619 1.00 3.18  ? 380 ARG A CG  1 
ATOM 1243 C CD  . ARG A 1 380 ? 183.383 138.529 137.316 1.00 2.14  ? 380 ARG A CD  1 
ATOM 1244 N NE  . ARG A 1 380 ? 181.950 138.790 137.371 1.00 2.14  ? 380 ARG A NE  1 
ATOM 1245 C CZ  . ARG A 1 380 ? 181.012 137.852 137.326 1.00 3.47  ? 380 ARG A CZ  1 
ATOM 1246 N NH1 . ARG A 1 380 ? 181.321 136.567 137.261 1.00 5.18  ? 380 ARG A NH1 1 
ATOM 1247 N NH2 . ARG A 1 380 ? 179.733 138.212 137.345 1.00 3.14  ? 380 ARG A NH2 1 
ATOM 1248 N N   . VAL A 1 381 ? 183.742 139.952 142.670 1.00 1.03  ? 381 VAL A N   1 
ATOM 1249 C CA  . VAL A 1 381 ? 184.255 141.129 143.363 1.00 0.00  ? 381 VAL A CA  1 
ATOM 1250 C C   . VAL A 1 381 ? 185.142 140.727 144.532 1.00 0.00  ? 381 VAL A C   1 
ATOM 1251 O O   . VAL A 1 381 ? 186.220 141.297 144.732 1.00 0.00  ? 381 VAL A O   1 
ATOM 1252 C CB  . VAL A 1 381 ? 183.089 142.029 143.818 1.00 3.49  ? 381 VAL A CB  1 
ATOM 1253 C CG1 . VAL A 1 381 ? 183.490 142.868 145.028 1.00 0.78  ? 381 VAL A CG1 1 
ATOM 1254 C CG2 . VAL A 1 381 ? 182.631 142.924 142.680 1.00 0.39  ? 381 VAL A CG2 1 
ATOM 1255 N N   . PHE A 1 382 ? 184.711 139.749 145.329 1.00 4.89  ? 382 PHE A N   1 
ATOM 1256 C CA  . PHE A 1 382 ? 185.467 139.430 146.534 1.00 4.19  ? 382 PHE A CA  1 
ATOM 1257 C C   . PHE A 1 382 ? 186.747 138.654 146.245 1.00 3.39  ? 382 PHE A C   1 
ATOM 1258 O O   . PHE A 1 382 ? 187.659 138.664 147.077 1.00 2.89  ? 382 PHE A O   1 
ATOM 1259 C CB  . PHE A 1 382 ? 184.583 138.679 147.528 1.00 2.47  ? 382 PHE A CB  1 
ATOM 1260 C CG  . PHE A 1 382 ? 183.874 139.588 148.491 1.00 2.53  ? 382 PHE A CG  1 
ATOM 1261 C CD1 . PHE A 1 382 ? 184.498 140.008 149.654 1.00 3.66  ? 382 PHE A CD1 1 
ATOM 1262 C CD2 . PHE A 1 382 ? 182.600 140.053 148.215 1.00 2.26  ? 382 PHE A CD2 1 
ATOM 1263 C CE1 . PHE A 1 382 ? 183.855 140.857 150.534 1.00 2.10  ? 382 PHE A CE1 1 
ATOM 1264 C CE2 . PHE A 1 382 ? 181.952 140.901 149.093 1.00 0.84  ? 382 PHE A CE2 1 
ATOM 1265 C CZ  . PHE A 1 382 ? 182.581 141.305 150.252 1.00 0.90  ? 382 PHE A CZ  1 
ATOM 1266 N N   . THR A 1 383 ? 186.835 137.987 145.100 1.00 1.66  ? 383 THR A N   1 
ATOM 1267 C CA  . THR A 1 383 ? 188.109 137.497 144.568 1.00 1.00  ? 383 THR A CA  1 
ATOM 1268 C C   . THR A 1 383 ? 188.689 138.491 143.566 1.00 4.50  ? 383 THR A C   1 
ATOM 1269 O O   . THR A 1 383 ? 189.029 138.145 142.436 1.00 8.21  ? 383 THR A O   1 
ATOM 1270 C CB  . THR A 1 383 ? 187.926 136.121 143.936 1.00 4.39  ? 383 THR A CB  1 
ATOM 1271 O OG1 . THR A 1 383 ? 187.242 136.251 142.683 1.00 4.90  ? 383 THR A OG1 1 
ATOM 1272 C CG2 . THR A 1 383 ? 187.118 135.220 144.854 1.00 0.00  ? 383 THR A CG2 1 
ATOM 1273 N N   . ALA A 1 384 ? 188.817 139.744 144.003 1.00 6.92  ? 384 ALA A N   1 
ATOM 1274 C CA  . ALA A 1 384 ? 189.096 140.848 143.085 1.00 0.10  ? 384 ALA A CA  1 
ATOM 1275 C C   . ALA A 1 384 ? 190.370 140.712 142.255 1.00 8.73  ? 384 ALA A C   1 
ATOM 1276 O O   . ALA A 1 384 ? 190.345 141.136 141.086 1.00 11.25 ? 384 ALA A O   1 
ATOM 1277 C CB  . ALA A 1 384 ? 189.115 142.168 143.864 1.00 1.84  ? 384 ALA A CB  1 
ATOM 1278 N N   . PRO A 1 385 ? 191.505 140.212 142.773 1.00 6.11  ? 385 PRO A N   1 
ATOM 1279 C CA  . PRO A 1 385 ? 192.718 140.183 141.931 1.00 1.12  ? 385 PRO A CA  1 
ATOM 1280 C C   . PRO A 1 385 ? 192.547 139.432 140.619 1.00 5.99  ? 385 PRO A C   1 
ATOM 1281 O O   . PRO A 1 385 ? 193.099 139.858 139.598 1.00 5.60  ? 385 PRO A O   1 
ATOM 1282 C CB  . PRO A 1 385 ? 193.757 139.512 142.838 1.00 1.81  ? 385 PRO A CB  1 
ATOM 1283 C CG  . PRO A 1 385 ? 193.301 139.799 144.206 1.00 4.45  ? 385 PRO A CG  1 
ATOM 1284 C CD  . PRO A 1 385 ? 191.804 139.829 144.165 1.00 0.10  ? 385 PRO A CD  1 
ATOM 1285 N N   . PHE A 1 386 ? 191.802 138.331 140.608 1.00 5.71  ? 386 PHE A N   1 
ATOM 1286 C CA  . PHE A 1 386 ? 191.500 137.632 139.366 1.00 5.21  ? 386 PHE A CA  1 
ATOM 1287 C C   . PHE A 1 386 ? 190.458 137.326 138.290 1.00 8.89  ? 386 PHE A C   1 
ATOM 1288 O O   . PHE A 1 386 ? 190.575 136.346 137.551 1.00 16.03 ? 386 PHE A O   1 
ATOM 1289 C CB  . PHE A 1 386 ? 191.297 136.145 139.635 1.00 4.48  ? 386 PHE A CB  1 
ATOM 1290 C CG  . PHE A 1 386 ? 192.217 135.591 140.683 1.00 7.38  ? 386 PHE A CG  1 
ATOM 1291 C CD1 . PHE A 1 386 ? 193.566 135.424 140.421 1.00 7.77  ? 386 PHE A CD1 1 
ATOM 1292 C CD2 . PHE A 1 386 ? 191.735 135.244 141.934 1.00 8.22  ? 386 PHE A CD2 1 
ATOM 1293 C CE1 . PHE A 1 386 ? 194.417 134.916 141.385 1.00 7.17  ? 386 PHE A CE1 1 
ATOM 1294 C CE2 . PHE A 1 386 ? 192.581 134.739 142.902 1.00 8.57  ? 386 PHE A CE2 1 
ATOM 1295 C CZ  . PHE A 1 386 ? 193.924 134.575 142.626 1.00 8.13  ? 386 PHE A CZ  1 
ATOM 1296 N N   . HIS A 1 387 ? 189.424 138.163 138.184 1.00 4.38  ? 387 HIS A N   1 
ATOM 1297 C CA  . HIS A 1 387 ? 188.475 138.093 137.073 1.00 5.17  ? 387 HIS A CA  1 
ATOM 1298 C C   . HIS A 1 387 ? 189.085 139.471 136.796 1.00 7.54  ? 387 HIS A C   1 
ATOM 1299 O O   . HIS A 1 387 ? 189.711 140.088 137.661 1.00 11.96 ? 387 HIS A O   1 
ATOM 1300 C CB  . HIS A 1 387 ? 187.330 137.836 138.057 1.00 4.14  ? 387 HIS A CB  1 
ATOM 1301 C CG  . HIS A 1 387 ? 187.241 136.419 138.523 1.00 6.24  ? 387 HIS A CG  1 
ATOM 1302 N ND1 . HIS A 1 387 ? 187.200 136.075 139.856 1.00 5.35  ? 387 HIS A ND1 1 
ATOM 1303 C CD2 . HIS A 1 387 ? 187.189 135.256 137.832 1.00 5.60  ? 387 HIS A CD2 1 
ATOM 1304 C CE1 . HIS A 1 387 ? 187.124 134.761 139.967 1.00 7.81  ? 387 HIS A CE1 1 
ATOM 1305 N NE2 . HIS A 1 387 ? 187.115 134.240 138.754 1.00 8.90  ? 387 HIS A NE2 1 
ATOM 1306 N N   . LYS A 1 388 ? 188.915 139.909 135.543 1.00 10.91 ? 388 LYS A N   1 
ATOM 1307 C CA  . LYS A 1 388 ? 189.511 141.144 135.036 1.00 1.16  ? 388 LYS A CA  1 
ATOM 1308 C C   . LYS A 1 388 ? 188.265 142.023 135.091 1.00 1.89  ? 388 LYS A C   1 
ATOM 1309 O O   . LYS A 1 388 ? 187.142 141.559 134.879 1.00 5.22  ? 388 LYS A O   1 
ATOM 1310 C CB  . LYS A 1 388 ? 190.040 141.057 133.597 1.00 5.97  ? 388 LYS A CB  1 
ATOM 1311 C CG  . LYS A 1 388 ? 189.054 141.465 132.508 1.00 3.97  ? 388 LYS A CG  1 
ATOM 1312 C CD  . LYS A 1 388 ? 189.751 141.666 131.173 1.00 6.45  ? 388 LYS A CD  1 
ATOM 1313 C CE  . LYS A 1 388 ? 188.905 142.499 130.223 1.00 8.81  ? 388 LYS A CE  1 
ATOM 1314 N NZ  . LYS A 1 388 ? 188.872 143.932 130.621 1.00 10.28 ? 388 LYS A NZ  1 
ATOM 1315 N N   . VAL A 1 389 ? 188.484 143.300 135.382 1.00 4.17  ? 389 VAL A N   1 
ATOM 1316 C CA  . VAL A 1 389 ? 187.450 144.174 135.926 1.00 1.55  ? 389 VAL A CA  1 
ATOM 1317 C C   . VAL A 1 389 ? 186.588 144.738 134.804 1.00 1.74  ? 389 VAL A C   1 
ATOM 1318 O O   . VAL A 1 389 ? 187.066 145.508 133.966 1.00 10.33 ? 389 VAL A O   1 
ATOM 1319 C CB  . VAL A 1 389 ? 188.074 145.307 136.753 1.00 1.19  ? 389 VAL A CB  1 
ATOM 1320 C CG1 . VAL A 1 389 ? 186.991 146.151 137.410 1.00 0.80  ? 389 VAL A CG1 1 
ATOM 1321 C CG2 . VAL A 1 389 ? 189.029 144.740 137.790 1.00 1.76  ? 389 VAL A CG2 1 
ATOM 1322 N N   . GLY A 1 390 ? 185.308 144.362 134.799 1.00 0.00  ? 390 GLY A N   1 
ATOM 1323 C CA  . GLY A 1 390 ? 184.311 145.057 134.016 1.00 0.96  ? 390 GLY A CA  1 
ATOM 1324 C C   . GLY A 1 390 ? 183.684 146.189 134.813 1.00 2.48  ? 390 GLY A C   1 
ATOM 1325 O O   . GLY A 1 390 ? 184.071 146.480 135.943 1.00 0.00  ? 390 GLY A O   1 
ATOM 1326 N N   . PHE A 1 391 ? 182.689 146.836 134.202 1.00 0.00  ? 391 PHE A N   1 
ATOM 1327 C CA  . PHE A 1 391 ? 182.034 147.961 134.866 1.00 1.14  ? 391 PHE A CA  1 
ATOM 1328 C C   . PHE A 1 391 ? 181.304 147.525 136.134 1.00 0.82  ? 391 PHE A C   1 
ATOM 1329 O O   . PHE A 1 391 ? 181.414 148.173 137.183 1.00 0.00  ? 391 PHE A O   1 
ATOM 1330 C CB  . PHE A 1 391 ? 181.068 148.666 133.909 1.00 0.00  ? 391 PHE A CB  1 
ATOM 1331 C CG  . PHE A 1 391 ? 180.157 149.657 134.590 1.00 0.00  ? 391 PHE A CG  1 
ATOM 1332 C CD1 . PHE A 1 391 ? 180.545 150.971 134.781 1.00 0.00  ? 391 PHE A CD1 1 
ATOM 1333 C CD2 . PHE A 1 391 ? 178.901 149.270 135.026 1.00 0.00  ? 391 PHE A CD2 1 
ATOM 1334 C CE1 . PHE A 1 391 ? 179.711 151.872 135.417 1.00 0.00  ? 391 PHE A CE1 1 
ATOM 1335 C CE2 . PHE A 1 391 ? 178.064 150.165 135.655 1.00 0.00  ? 391 PHE A CE2 1 
ATOM 1336 C CZ  . PHE A 1 391 ? 178.467 151.467 135.851 1.00 0.00  ? 391 PHE A CZ  1 
ATOM 1337 N N   . ALA A 1 392 ? 180.538 146.436 136.050 1.00 0.00  ? 392 ALA A N   1 
ATOM 1338 C CA  . ALA A 1 392 ? 179.704 146.029 137.176 1.00 0.00  ? 392 ALA A CA  1 
ATOM 1339 C C   . ALA A 1 392 ? 180.552 145.668 138.388 1.00 0.00  ? 392 ALA A C   1 
ATOM 1340 O O   . ALA A 1 392 ? 180.169 145.953 139.528 1.00 0.00  ? 392 ALA A O   1 
ATOM 1341 C CB  . ALA A 1 392 ? 178.809 144.859 136.767 1.00 0.00  ? 392 ALA A CB  1 
ATOM 1342 N N   . ASP A 1 393 ? 181.718 145.059 138.155 1.00 0.95  ? 393 ASP A N   1 
ATOM 1343 C CA  . ASP A 1 393 ? 182.609 144.697 139.253 1.00 2.69  ? 393 ASP A CA  1 
ATOM 1344 C C   . ASP A 1 393 ? 183.051 145.925 140.044 1.00 0.00  ? 393 ASP A C   1 
ATOM 1345 O O   . ASP A 1 393 ? 182.894 145.971 141.273 1.00 0.00  ? 393 ASP A O   1 
ATOM 1346 C CB  . ASP A 1 393 ? 183.827 143.941 138.718 1.00 0.00  ? 393 ASP A CB  1 
ATOM 1347 C CG  . ASP A 1 393 ? 183.451 142.799 137.801 1.00 1.27  ? 393 ASP A CG  1 
ATOM 1348 O OD1 . ASP A 1 393 ? 182.728 143.043 136.815 1.00 7.29  ? 393 ASP A OD1 1 
ATOM 1349 O OD2 . ASP A 1 393 ? 183.885 141.658 138.063 1.00 9.08  ? 393 ASP A OD2 1 
ATOM 1350 N N   . PHE A 1 394 ? 183.710 146.787 139.180 1.00 0.00  ? 394 PHE A N   1 
ATOM 1351 C CA  . PHE A 1 394 ? 184.143 148.125 139.582 1.00 1.89  ? 394 PHE A CA  1 
ATOM 1352 C C   . PHE A 1 394 ? 183.047 148.886 140.493 1.00 0.00  ? 394 PHE A C   1 
ATOM 1353 O O   . PHE A 1 394 ? 183.371 149.253 141.575 1.00 0.00  ? 394 PHE A O   1 
ATOM 1354 C CB  . PHE A 1 394 ? 184.657 149.014 138.394 1.00 1.81  ? 394 PHE A CB  1 
ATOM 1355 C CG  . PHE A 1 394 ? 184.322 150.482 138.561 1.00 0.08  ? 394 PHE A CG  1 
ATOM 1356 C CD1 . PHE A 1 394 ? 185.041 151.270 139.451 1.00 0.94  ? 394 PHE A CD1 1 
ATOM 1357 C CD2 . PHE A 1 394 ? 183.213 151.040 137.942 1.00 3.25  ? 394 PHE A CD2 1 
ATOM 1358 C CE1 . PHE A 1 394 ? 184.709 152.594 139.616 1.00 0.09  ? 394 PHE A CE1 1 
ATOM 1359 C CE2 . PHE A 1 394 ? 182.861 152.344 138.160 1.00 7.25  ? 394 PHE A CE2 1 
ATOM 1360 C CZ  . PHE A 1 394 ? 183.595 153.126 139.012 1.00 1.87  ? 394 PHE A CZ  1 
ATOM 1361 N N   . TRP A 1 395 ? 181.855 148.914 140.003 1.00 0.00  ? 395 TRP A N   1 
ATOM 1362 C CA  . TRP A 1 395 ? 180.696 149.656 140.488 1.00 0.00  ? 395 TRP A CA  1 
ATOM 1363 C C   . TRP A 1 395 ? 180.166 149.053 141.782 1.00 0.00  ? 395 TRP A C   1 
ATOM 1364 O O   . TRP A 1 395 ? 179.881 149.779 142.739 1.00 0.00  ? 395 TRP A O   1 
ATOM 1365 C CB  . TRP A 1 395 ? 179.600 149.694 139.416 1.00 0.00  ? 395 TRP A CB  1 
ATOM 1366 C CG  . TRP A 1 395 ? 178.404 150.533 139.787 1.00 0.00  ? 395 TRP A CG  1 
ATOM 1367 C CD1 . TRP A 1 395 ? 178.250 151.874 139.587 1.00 0.00  ? 395 TRP A CD1 1 
ATOM 1368 C CD2 . TRP A 1 395 ? 177.206 150.087 140.437 1.00 0.00  ? 395 TRP A CD2 1 
ATOM 1369 N NE1 . TRP A 1 395 ? 177.033 152.289 140.065 1.00 0.00  ? 395 TRP A NE1 1 
ATOM 1370 C CE2 . TRP A 1 395 ? 176.372 151.212 140.593 1.00 0.00  ? 395 TRP A CE2 1 
ATOM 1371 C CE3 . TRP A 1 395 ? 176.757 148.846 140.898 1.00 0.00  ? 395 TRP A CE3 1 
ATOM 1372 C CZ2 . TRP A 1 395 ? 175.116 151.134 141.189 1.00 0.00  ? 395 TRP A CZ2 1 
ATOM 1373 C CZ3 . TRP A 1 395 ? 175.510 148.770 141.489 1.00 0.00  ? 395 TRP A CZ3 1 
ATOM 1374 C CH2 . TRP A 1 395 ? 174.705 149.908 141.632 1.00 0.00  ? 395 TRP A CH2 1 
ATOM 1375 N N   . LEU A 1 396 ? 180.055 147.723 141.841 1.00 0.00  ? 396 LEU A N   1 
ATOM 1376 C CA  . LEU A 1 396 ? 179.638 147.072 143.078 1.00 0.00  ? 396 LEU A CA  1 
ATOM 1377 C C   . LEU A 1 396 ? 180.680 147.254 144.176 1.00 0.00  ? 396 LEU A C   1 
ATOM 1378 O O   . LEU A 1 396 ? 180.327 147.439 145.347 1.00 0.00  ? 396 LEU A O   1 
ATOM 1379 C CB  . LEU A 1 396 ? 179.365 145.587 142.828 1.00 0.03  ? 396 LEU A CB  1 
ATOM 1380 C CG  . LEU A 1 396 ? 178.867 144.786 144.036 1.00 1.59  ? 396 LEU A CG  1 
ATOM 1381 C CD1 . LEU A 1 396 ? 177.505 145.289 144.492 1.00 0.00  ? 396 LEU A CD1 1 
ATOM 1382 C CD2 . LEU A 1 396 ? 178.823 143.290 143.737 1.00 0.52  ? 396 LEU A CD2 1 
ATOM 1383 N N   . ALA A 1 397 ? 181.968 147.213 143.821 1.00 0.00  ? 397 ALA A N   1 
ATOM 1384 C CA  . ALA A 1 397 ? 183.006 147.455 144.819 1.00 0.07  ? 397 ALA A CA  1 
ATOM 1385 C C   . ALA A 1 397 ? 182.912 148.869 145.393 1.00 0.15  ? 397 ALA A C   1 
ATOM 1386 O O   . ALA A 1 397 ? 183.089 149.071 146.599 1.00 1.22  ? 397 ALA A O   1 
ATOM 1387 C CB  . ALA A 1 397 ? 184.384 147.200 144.211 1.00 0.00  ? 397 ALA A CB  1 
ATOM 1388 N N   . ASP A 1 398 ? 182.625 149.860 144.546 1.00 0.00  ? 398 ASP A N   1 
ATOM 1389 C CA  . ASP A 1 398 ? 182.434 151.229 145.023 1.00 0.00  ? 398 ASP A CA  1 
ATOM 1390 C C   . ASP A 1 398 ? 181.192 151.350 145.905 1.00 0.00  ? 398 ASP A C   1 
ATOM 1391 O O   . ASP A 1 398 ? 181.221 152.035 146.940 1.00 1.82  ? 398 ASP A O   1 
ATOM 1392 C CB  . ASP A 1 398 ? 182.350 152.193 143.837 1.00 0.46  ? 398 ASP A CB  1 
ATOM 1393 C CG  . ASP A 1 398 ? 183.686 152.380 143.139 1.00 0.24  ? 398 ASP A CG  1 
ATOM 1394 O OD1 . ASP A 1 398 ? 184.723 152.005 143.717 1.00 0.52  ? 398 ASP A OD1 1 
ATOM 1395 O OD2 . ASP A 1 398 ? 183.699 152.912 142.010 1.00 1.19  ? 398 ASP A OD2 1 
ATOM 1396 N N   . GLN A 1 399 ? 180.089 150.699 145.511 1.00 0.00  ? 399 GLN A N   1 
ATOM 1397 C CA  . GLN A 1 399 ? 178.909 150.675 146.375 1.00 0.00  ? 399 GLN A CA  1 
ATOM 1398 C C   . GLN A 1 399 ? 179.260 150.100 147.744 1.00 3.52  ? 399 GLN A C   1 
ATOM 1399 O O   . GLN A 1 399 ? 178.788 150.592 148.775 1.00 0.00  ? 399 GLN A O   1 
ATOM 1400 C CB  . GLN A 1 399 ? 177.769 149.865 145.742 1.00 0.00  ? 399 GLN A CB  1 
ATOM 1401 C CG  . GLN A 1 399 ? 177.375 150.192 144.289 1.00 0.00  ? 399 GLN A CG  1 
ATOM 1402 C CD  . GLN A 1 399 ? 177.147 151.669 144.017 1.00 0.00  ? 399 GLN A CD  1 
ATOM 1403 O OE1 . GLN A 1 399 ? 176.178 152.255 144.491 1.00 0.00  ? 399 GLN A OE1 1 
ATOM 1404 N NE2 . GLN A 1 399 ? 178.034 152.270 143.232 1.00 0.00  ? 399 GLN A NE2 1 
ATOM 1405 N N   . LEU A 1 400 ? 180.094 149.055 147.768 1.00 0.00  ? 400 LEU A N   1 
ATOM 1406 C CA  . LEU A 1 400 ? 180.563 148.502 149.035 1.00 1.00  ? 400 LEU A CA  1 
ATOM 1407 C C   . LEU A 1 400 ? 181.392 149.520 149.807 1.00 0.00  ? 400 LEU A C   1 
ATOM 1408 O O   . LEU A 1 400 ? 181.291 149.612 151.035 1.00 0.00  ? 400 LEU A O   1 
ATOM 1409 C CB  . LEU A 1 400 ? 181.376 147.232 148.789 1.00 0.00  ? 400 LEU A CB  1 
ATOM 1410 C CG  . LEU A 1 400 ? 180.598 146.004 148.324 1.00 0.00  ? 400 LEU A CG  1 
ATOM 1411 C CD1 . LEU A 1 400 ? 181.523 144.806 148.201 1.00 1.10  ? 400 LEU A CD1 1 
ATOM 1412 C CD2 . LEU A 1 400 ? 179.445 145.708 149.268 1.00 1.05  ? 400 LEU A CD2 1 
ATOM 1413 N N   . ASN A 1 401 ? 182.234 150.280 149.102 1.00 0.47  ? 401 ASN A N   1 
ATOM 1414 C CA  . ASN A 1 401 ? 182.988 151.344 149.757 1.00 0.73  ? 401 ASN A CA  1 
ATOM 1415 C C   . ASN A 1 401 ? 182.059 152.348 150.422 1.00 0.00  ? 401 ASN A C   1 
ATOM 1416 O O   . ASN A 1 401 ? 182.426 152.965 151.427 1.00 2.65  ? 401 ASN A O   1 
ATOM 1417 C CB  . ASN A 1 401 ? 183.898 152.057 148.758 1.00 0.43  ? 401 ASN A CB  1 
ATOM 1418 C CG  . ASN A 1 401 ? 185.277 151.440 148.681 1.00 0.71  ? 401 ASN A CG  1 
ATOM 1419 O OD1 . ASN A 1 401 ? 186.242 151.983 149.213 1.00 0.00  ? 401 ASN A OD1 1 
ATOM 1420 N ND2 . ASN A 1 401 ? 185.377 150.301 148.009 1.00 0.00  ? 401 ASN A ND2 1 
ATOM 1421 N N   . SER A 1 402 ? 180.860 152.529 149.879 1.00 2.51  ? 402 SER A N   1 
ATOM 1422 C CA  . SER A 1 402 ? 179.853 153.346 150.544 1.00 1.84  ? 402 SER A CA  1 
ATOM 1423 C C   . SER A 1 402 ? 179.025 152.569 151.566 1.00 0.73  ? 402 SER A C   1 
ATOM 1424 O O   . SER A 1 402 ? 178.199 153.173 152.256 1.00 0.00  ? 402 SER A O   1 
ATOM 1425 C CB  . SER A 1 402 ? 178.923 153.987 149.512 1.00 1.10  ? 402 SER A CB  1 
ATOM 1426 O OG  . SER A 1 402 ? 177.809 154.591 150.140 1.00 2.10  ? 402 SER A OG  1 
ATOM 1427 N N   . LEU A 1 403 ? 179.223 151.256 151.686 1.00 0.00  ? 403 LEU A N   1 
ATOM 1428 C CA  . LEU A 1 403 ? 178.433 150.421 152.586 1.00 0.00  ? 403 LEU A CA  1 
ATOM 1429 C C   . LEU A 1 403 ? 179.303 149.664 153.587 1.00 0.61  ? 403 LEU A C   1 
ATOM 1430 O O   . LEU A 1 403 ? 178.916 148.597 154.066 1.00 0.00  ? 403 LEU A O   1 
ATOM 1431 C CB  . LEU A 1 403 ? 177.572 149.438 151.794 1.00 0.00  ? 403 LEU A CB  1 
ATOM 1432 C CG  . LEU A 1 403 ? 176.348 149.983 151.058 1.00 0.00  ? 403 LEU A CG  1 
ATOM 1433 C CD1 . LEU A 1 403 ? 175.778 148.928 150.123 1.00 1.98  ? 403 LEU A CD1 1 
ATOM 1434 C CD2 . LEU A 1 403 ? 175.293 150.454 152.041 1.00 2.17  ? 403 LEU A CD2 1 
ATOM 1435 N N   . SER A 1 404 ? 180.479 150.204 153.920 1.00 2.72  ? 404 SER A N   1 
ATOM 1436 C CA  . SER A 1 404 ? 181.400 149.483 154.796 1.00 2.12  ? 404 SER A CA  1 
ATOM 1437 C C   . SER A 1 404 ? 180.847 149.336 156.209 1.00 1.11  ? 404 SER A C   1 
ATOM 1438 O O   . SER A 1 404 ? 181.304 148.473 156.967 1.00 0.60  ? 404 SER A O   1 
ATOM 1439 C CB  . SER A 1 404 ? 182.757 150.188 154.834 1.00 1.68  ? 404 SER A CB  1 
ATOM 1440 O OG  . SER A 1 404 ? 182.676 151.416 155.536 1.00 3.83  ? 404 SER A OG  1 
ATOM 1441 N N   . VAL A 1 405 ? 179.867 150.163 156.577 1.00 1.33  ? 405 VAL A N   1 
ATOM 1442 C CA  . VAL A 1 405 ? 179.293 150.115 157.918 1.00 1.68  ? 405 VAL A CA  1 
ATOM 1443 C C   . VAL A 1 405 ? 178.586 148.787 158.169 1.00 0.39  ? 405 VAL A C   1 
ATOM 1444 O O   . VAL A 1 405 ? 178.523 148.317 159.310 1.00 6.15  ? 405 VAL A O   1 
ATOM 1445 C CB  . VAL A 1 405 ? 178.355 151.324 158.120 1.00 2.58  ? 405 VAL A CB  1 
ATOM 1446 C CG1 . VAL A 1 405 ? 177.376 151.424 156.972 1.00 1.68  ? 405 VAL A CG1 1 
ATOM 1447 C CG2 . VAL A 1 405 ? 177.624 151.243 159.454 1.00 0.99  ? 405 VAL A CG2 1 
ATOM 1448 N N   . ILE A 1 406 ? 178.064 148.149 157.120 1.00 1.34  ? 406 ILE A N   1 
ATOM 1449 C CA  . ILE A 1 406 ? 177.417 146.850 157.288 1.00 2.60  ? 406 ILE A CA  1 
ATOM 1450 C C   . ILE A 1 406 ? 178.432 145.784 157.700 1.00 2.65  ? 406 ILE A C   1 
ATOM 1451 O O   . ILE A 1 406 ? 178.146 144.933 158.551 1.00 7.28  ? 406 ILE A O   1 
ATOM 1452 C CB  . ILE A 1 406 ? 176.664 146.462 156.003 1.00 3.71  ? 406 ILE A CB  1 
ATOM 1453 C CG1 . ILE A 1 406 ? 175.556 147.479 155.717 1.00 0.00  ? 406 ILE A CG1 1 
ATOM 1454 C CG2 . ILE A 1 406 ? 176.087 145.062 156.116 1.00 1.59  ? 406 ILE A CG2 1 
ATOM 1455 C CD1 . ILE A 1 406 ? 174.873 147.288 154.385 1.00 1.70  ? 406 ILE A CD1 1 
ATOM 1456 N N   . LEU A 1 407 ? 179.629 145.808 157.106 1.00 1.70  ? 407 LEU A N   1 
ATOM 1457 C CA  . LEU A 1 407 ? 180.659 144.842 157.484 1.00 0.63  ? 407 LEU A CA  1 
ATOM 1458 C C   . LEU A 1 407 ? 181.133 145.066 158.916 1.00 5.41  ? 407 LEU A C   1 
ATOM 1459 O O   . LEU A 1 407 ? 181.375 144.101 159.656 1.00 4.92  ? 407 LEU A O   1 
ATOM 1460 C CB  . LEU A 1 407 ? 181.833 144.915 156.508 1.00 3.00  ? 407 LEU A CB  1 
ATOM 1461 C CG  . LEU A 1 407 ? 181.491 144.796 155.020 1.00 3.63  ? 407 LEU A CG  1 
ATOM 1462 C CD1 . LEU A 1 407 ? 182.757 144.725 154.178 1.00 1.70  ? 407 LEU A CD1 1 
ATOM 1463 C CD2 . LEU A 1 407 ? 180.606 143.585 154.764 1.00 3.39  ? 407 LEU A CD2 1 
ATOM 1464 N N   . MET A 1 408 ? 181.274 146.330 159.326 1.00 1.50  ? 408 MET A N   1 
ATOM 1465 C CA  . MET A 1 408 ? 181.612 146.621 160.715 1.00 2.04  ? 408 MET A CA  1 
ATOM 1466 C C   . MET A 1 408 ? 180.508 146.163 161.654 1.00 3.64  ? 408 MET A C   1 
ATOM 1467 O O   . MET A 1 408 ? 180.784 145.663 162.748 1.00 4.86  ? 408 MET A O   1 
ATOM 1468 C CB  . MET A 1 408 ? 181.883 148.114 160.899 1.00 3.13  ? 408 MET A CB  1 
ATOM 1469 C CG  . MET A 1 408 ? 182.776 148.717 159.840 1.00 3.09  ? 408 MET A CG  1 
ATOM 1470 S SD  . MET A 1 408 ? 184.455 148.089 159.993 1.00 9.75  ? 408 MET A SD  1 
ATOM 1471 C CE  . MET A 1 408 ? 184.999 148.932 161.474 1.00 1.03  ? 408 MET A CE  1 
ATOM 1472 N N   . ASP A 1 409 ? 179.249 146.337 161.249 1.00 1.94  ? 409 ASP A N   1 
ATOM 1473 C CA  . ASP A 1 409 ? 178.137 145.863 162.064 1.00 3.10  ? 409 ASP A CA  1 
ATOM 1474 C C   . ASP A 1 409 ? 178.167 144.348 162.199 1.00 3.32  ? 409 ASP A C   1 
ATOM 1475 O O   . ASP A 1 409 ? 177.872 143.809 163.268 1.00 9.11  ? 409 ASP A O   1 
ATOM 1476 C CB  . ASP A 1 409 ? 176.810 146.330 161.465 1.00 4.82  ? 409 ASP A CB  1 
ATOM 1477 C CG  . ASP A 1 409 ? 176.517 147.787 161.765 1.00 4.40  ? 409 ASP A CG  1 
ATOM 1478 O OD1 . ASP A 1 409 ? 177.215 148.371 162.619 1.00 4.96  ? 409 ASP A OD1 1 
ATOM 1479 O OD2 . ASP A 1 409 ? 175.595 148.351 161.141 1.00 5.21  ? 409 ASP A OD2 1 
ATOM 1480 N N   . LEU A 1 410 ? 178.525 143.645 161.124 1.00 6.85  ? 410 LEU A N   1 
ATOM 1481 C CA  . LEU A 1 410 ? 178.658 142.192 161.198 1.00 7.25  ? 410 LEU A CA  1 
ATOM 1482 C C   . LEU A 1 410 ? 179.785 141.780 162.141 1.00 3.44  ? 410 LEU A C   1 
ATOM 1483 O O   . LEU A 1 410 ? 179.626 140.850 162.941 1.00 7.40  ? 410 LEU A O   1 
ATOM 1484 C CB  . LEU A 1 410 ? 178.889 141.619 159.801 1.00 4.76  ? 410 LEU A CB  1 
ATOM 1485 C CG  . LEU A 1 410 ? 178.738 140.105 159.648 1.00 6.97  ? 410 LEU A CG  1 
ATOM 1486 C CD1 . LEU A 1 410 ? 177.875 139.776 158.444 1.00 5.37  ? 410 LEU A CD1 1 
ATOM 1487 C CD2 . LEU A 1 410 ? 180.100 139.438 159.530 1.00 5.46  ? 410 LEU A CD2 1 
ATOM 1488 N N   . GLU A 1 411 ? 180.934 142.455 162.056 1.00 2.75  ? 411 GLU A N   1 
ATOM 1489 C CA  . GLU A 1 411 ? 182.039 142.147 162.962 1.00 3.18  ? 411 GLU A CA  1 
ATOM 1490 C C   . GLU A 1 411 ? 181.656 142.424 164.413 1.00 8.27  ? 411 GLU A C   1 
ATOM 1491 O O   . GLU A 1 411 ? 181.987 141.642 165.316 1.00 8.07  ? 411 GLU A O   1 
ATOM 1492 C CB  . GLU A 1 411 ? 183.279 142.950 162.567 1.00 2.57  ? 411 GLU A CB  1 
ATOM 1493 C CG  . GLU A 1 411 ? 184.590 142.344 163.037 1.00 2.68  ? 411 GLU A CG  1 
ATOM 1494 C CD  . GLU A 1 411 ? 185.203 143.104 164.199 1.00 6.77  ? 411 GLU A CD  1 
ATOM 1495 O OE1 . GLU A 1 411 ? 184.496 143.927 164.818 1.00 11.75 ? 411 GLU A OE1 1 
ATOM 1496 O OE2 . GLU A 1 411 ? 186.394 142.878 164.494 1.00 7.47  ? 411 GLU A OE2 1 
ATOM 1497 N N   . TYR A 1 412 ? 180.955 143.533 164.653 1.00 6.09  ? 412 TYR A N   1 
ATOM 1498 C CA  . TYR A 1 412 ? 180.472 143.854 165.991 1.00 10.16 ? 412 TYR A CA  1 
ATOM 1499 C C   . TYR A 1 412 ? 179.473 142.812 166.477 1.00 8.23  ? 412 TYR A C   1 
ATOM 1500 O O   . TYR A 1 412 ? 179.472 142.444 167.654 1.00 7.96  ? 412 TYR A O   1 
ATOM 1501 C CB  . TYR A 1 412 ? 179.851 145.255 165.991 1.00 4.83  ? 412 TYR A CB  1 
ATOM 1502 C CG  . TYR A 1 412 ? 179.210 145.667 167.296 1.00 4.69  ? 412 TYR A CG  1 
ATOM 1503 C CD1 . TYR A 1 412 ? 179.956 146.275 168.297 1.00 6.92  ? 412 TYR A CD1 1 
ATOM 1504 C CD2 . TYR A 1 412 ? 177.856 145.457 167.525 1.00 6.95  ? 412 TYR A CD2 1 
ATOM 1505 C CE1 . TYR A 1 412 ? 179.373 146.656 169.490 1.00 5.51  ? 412 TYR A CE1 1 
ATOM 1506 C CE2 . TYR A 1 412 ? 177.266 145.833 168.714 1.00 5.67  ? 412 TYR A CE2 1 
ATOM 1507 C CZ  . TYR A 1 412 ? 178.028 146.432 169.693 1.00 7.06  ? 412 TYR A CZ  1 
ATOM 1508 O OH  . TYR A 1 412 ? 177.442 146.810 170.879 1.00 9.29  ? 412 TYR A OH  1 
ATOM 1509 N N   . MET A 1 413 ? 178.604 142.336 165.582 1.00 6.01  ? 413 MET A N   1 
ATOM 1510 C CA  . MET A 1 413 ? 177.647 141.295 165.933 1.00 3.92  ? 413 MET A CA  1 
ATOM 1511 C C   . MET A 1 413 ? 178.352 140.010 166.339 1.00 6.78  ? 413 MET A C   1 
ATOM 1512 O O   . MET A 1 413 ? 177.984 139.386 167.341 1.00 10.99 ? 413 MET A O   1 
ATOM 1513 C CB  . MET A 1 413 ? 176.710 141.045 164.749 1.00 4.14  ? 413 MET A CB  1 
ATOM 1514 C CG  . MET A 1 413 ? 175.498 140.185 165.052 1.00 9.90  ? 413 MET A CG  1 
ATOM 1515 S SD  . MET A 1 413 ? 174.154 140.494 163.887 1.00 24.25 ? 413 MET A SD  1 
ATOM 1516 C CE  . MET A 1 413 ? 173.248 138.954 163.980 1.00 4.34  ? 413 MET A CE  1 
ATOM 1517 N N   . ILE A 1 414 ? 179.372 139.609 165.582 1.00 8.27  ? 414 ILE A N   1 
ATOM 1518 C CA  . ILE A 1 414 ? 180.180 138.439 165.902 1.00 6.45  ? 414 ILE A CA  1 
ATOM 1519 C C   . ILE A 1 414 ? 180.883 138.594 167.243 1.00 7.35  ? 414 ILE A C   1 
ATOM 1520 O O   . ILE A 1 414 ? 180.907 137.648 168.039 1.00 9.55  ? 414 ILE A O   1 
ATOM 1521 C CB  . ILE A 1 414 ? 181.194 138.134 164.786 1.00 7.02  ? 414 ILE A CB  1 
ATOM 1522 C CG1 . ILE A 1 414 ? 180.473 137.914 163.454 1.00 8.03  ? 414 ILE A CG1 1 
ATOM 1523 C CG2 . ILE A 1 414 ? 182.043 136.923 165.148 1.00 8.65  ? 414 ILE A CG2 1 
ATOM 1524 C CD1 . ILE A 1 414 ? 181.312 137.221 162.405 1.00 8.45  ? 414 ILE A CD1 1 
ATOM 1525 N N   . CYS A 1 415 ? 181.454 139.765 167.518 1.00 8.61  ? 415 CYS A N   1 
ATOM 1526 C CA  . CYS A 1 415 ? 182.092 140.035 168.802 1.00 4.58  ? 415 CYS A CA  1 
ATOM 1527 C C   . CYS A 1 415 ? 181.108 140.016 169.967 1.00 9.17  ? 415 CYS A C   1 
ATOM 1528 O O   . CYS A 1 415 ? 181.419 139.481 171.034 1.00 10.96 ? 415 CYS A O   1 
ATOM 1529 C CB  . CYS A 1 415 ? 182.812 141.388 168.756 1.00 5.02  ? 415 CYS A CB  1 
ATOM 1530 S SG  . CYS A 1 415 ? 184.332 141.461 169.728 1.00 17.69 ? 415 CYS A SG  1 
ATOM 1531 N N   . PHE A 1 416 ? 179.921 140.596 169.781 1.00 10.55 ? 416 PHE A N   1 
ATOM 1532 C CA  . PHE A 1 416 ? 178.972 140.743 170.878 1.00 7.72  ? 416 PHE A CA  1 
ATOM 1533 C C   . PHE A 1 416 ? 178.294 139.417 171.206 1.00 8.09  ? 416 PHE A C   1 
ATOM 1534 O O   . PHE A 1 416 ? 178.123 139.065 172.378 1.00 9.71  ? 416 PHE A O   1 
ATOM 1535 C CB  . PHE A 1 416 ? 177.938 141.814 170.521 1.00 6.92  ? 416 PHE A CB  1 
ATOM 1536 C CG  . PHE A 1 416 ? 176.738 141.833 171.426 1.00 7.88  ? 416 PHE A CG  1 
ATOM 1537 C CD1 . PHE A 1 416 ? 176.853 142.255 172.740 1.00 7.10  ? 416 PHE A CD1 1 
ATOM 1538 C CD2 . PHE A 1 416 ? 175.496 141.433 170.964 1.00 10.68 ? 416 PHE A CD2 1 
ATOM 1539 C CE1 . PHE A 1 416 ? 175.752 142.277 173.574 1.00 7.32  ? 416 PHE A CE1 1 
ATOM 1540 C CE2 . PHE A 1 416 ? 174.393 141.451 171.794 1.00 9.71  ? 416 PHE A CE2 1 
ATOM 1541 C CZ  . PHE A 1 416 ? 174.520 141.874 173.099 1.00 5.51  ? 416 PHE A CZ  1 
ATOM 1542 N N   . TYR A 1 417 ? 177.898 138.660 170.176 1.00 8.49  ? 417 TYR A N   1 
ATOM 1543 C CA  . TYR A 1 417 ? 177.210 137.396 170.418 1.00 10.64 ? 417 TYR A CA  1 
ATOM 1544 C C   . TYR A 1 417 ? 178.136 136.350 171.023 1.00 8.37  ? 417 TYR A C   1 
ATOM 1545 O O   . TYR A 1 417 ? 177.669 135.401 171.662 1.00 14.69 ? 417 TYR A O   1 
ATOM 1546 C CB  . TYR A 1 417 ? 176.600 136.863 169.120 1.00 8.76  ? 417 TYR A CB  1 
ATOM 1547 C CG  . TYR A 1 417 ? 175.173 137.305 168.876 1.00 9.89  ? 417 TYR A CG  1 
ATOM 1548 C CD1 . TYR A 1 417 ? 174.798 138.632 169.036 1.00 10.47 ? 417 TYR A CD1 1 
ATOM 1549 C CD2 . TYR A 1 417 ? 174.199 136.392 168.495 1.00 11.07 ? 417 TYR A CD2 1 
ATOM 1550 C CE1 . TYR A 1 417 ? 173.495 139.038 168.815 1.00 10.18 ? 417 TYR A CE1 1 
ATOM 1551 C CE2 . TYR A 1 417 ? 172.894 136.789 168.272 1.00 8.83  ? 417 TYR A CE2 1 
ATOM 1552 C CZ  . TYR A 1 417 ? 172.548 138.112 168.434 1.00 8.24  ? 417 TYR A CZ  1 
ATOM 1553 O OH  . TYR A 1 417 ? 171.249 138.511 168.213 1.00 10.83 ? 417 TYR A OH  1 
ATOM 1554 N N   . SER A 1 418 ? 179.446 136.496 170.828 1.00 9.37  ? 418 SER A N   1 
ATOM 1555 C CA  . SER A 1 418 ? 180.398 135.520 171.342 1.00 7.67  ? 418 SER A CA  1 
ATOM 1556 C C   . SER A 1 418 ? 180.836 135.863 172.761 1.00 10.66 ? 418 SER A C   1 
ATOM 1557 O O   . SER A 1 418 ? 180.701 135.040 173.672 1.00 14.43 ? 418 SER A O   1 
ATOM 1558 C CB  . SER A 1 418 ? 181.618 135.426 170.422 1.00 10.08 ? 418 SER A CB  1 
ATOM 1559 O OG  . SER A 1 418 ? 182.305 136.663 170.355 1.00 16.31 ? 418 SER A OG  1 
ATOM 1560 N N   . LEU A 1 419 ? 181.363 137.073 172.959 1.00 9.72  ? 419 LEU A N   1 
ATOM 1561 C CA  . LEU A 1 419 ? 181.910 137.440 174.262 1.00 10.89 ? 419 LEU A CA  1 
ATOM 1562 C C   . LEU A 1 419 ? 180.805 137.832 175.235 1.00 8.39  ? 419 LEU A C   1 
ATOM 1563 O O   . LEU A 1 419 ? 180.657 137.230 176.306 1.00 15.13 ? 419 LEU A O   1 
ATOM 1564 C CB  . LEU A 1 419 ? 182.921 138.578 174.104 1.00 8.24  ? 419 LEU A CB  1 
ATOM 1565 C CG  . LEU A 1 419 ? 184.185 138.293 173.288 1.00 8.11  ? 419 LEU A CG  1 
ATOM 1566 C CD1 . LEU A 1 419 ? 185.322 139.189 173.749 1.00 8.39  ? 419 LEU A CD1 1 
ATOM 1567 C CD2 . LEU A 1 419 ? 184.587 136.829 173.390 1.00 7.83  ? 419 LEU A CD2 1 
ATOM 1568 N N   . GLU A 1 420 ? 180.017 138.843 174.881 1.00 8.87  ? 420 GLU A N   1 
ATOM 1569 C CA  . GLU A 1 420 ? 178.959 139.332 175.755 1.00 10.46 ? 420 GLU A CA  1 
ATOM 1570 C C   . GLU A 1 420 ? 177.673 138.526 175.643 1.00 9.17  ? 420 GLU A C   1 
ATOM 1571 O O   . GLU A 1 420 ? 176.706 138.842 176.346 1.00 10.36 ? 420 GLU A O   1 
ATOM 1572 C CB  . GLU A 1 420 ? 178.670 140.805 175.453 1.00 8.72  ? 420 GLU A CB  1 
ATOM 1573 C CG  . GLU A 1 420 ? 179.743 141.762 175.943 1.00 8.62  ? 420 GLU A CG  1 
ATOM 1574 C CD  . GLU A 1 420 ? 179.550 143.169 175.418 1.00 12.31 ? 420 GLU A CD  1 
ATOM 1575 O OE1 . GLU A 1 420 ? 180.471 143.690 174.754 1.00 14.58 ? 420 GLU A OE1 1 
ATOM 1576 O OE2 . GLU A 1 420 ? 178.476 143.755 175.667 1.00 11.66 ? 420 GLU A OE2 1 
ATOM 1577 N N   . LEU A 1 421 ? 177.636 137.517 174.768 1.00 9.95  ? 421 LEU A N   1 
ATOM 1578 C CA  . LEU A 1 421 ? 176.481 136.644 174.571 1.00 7.68  ? 421 LEU A CA  1 
ATOM 1579 C C   . LEU A 1 421 ? 175.019 136.454 174.183 1.00 10.96 ? 421 LEU A C   1 
ATOM 1580 O O   . LEU A 1 421 ? 174.357 135.520 174.646 1.00 9.81  ? 421 LEU A O   1 
ATOM 1581 C CB  . LEU A 1 421 ? 176.085 135.952 175.881 1.00 7.56  ? 421 LEU A CB  1 
ATOM 1582 C CG  . LEU A 1 421 ? 177.136 135.084 176.583 1.00 10.40 ? 421 LEU A CG  1 
ATOM 1583 C CD1 . LEU A 1 421 ? 176.466 134.030 177.453 1.00 8.15  ? 421 LEU A CD1 1 
ATOM 1584 C CD2 . LEU A 1 421 ? 178.070 134.423 175.581 1.00 9.34  ? 421 LEU A CD2 1 
ATOM 1585 N N   . LYS A 1 422 ? 174.505 137.342 173.340 1.00 13.54 ? 422 LYS A N   1 
ATOM 1586 C CA  . LYS A 1 422 ? 173.105 137.296 172.940 1.00 9.14  ? 422 LYS A CA  1 
ATOM 1587 C C   . LYS A 1 422 ? 171.996 137.543 173.956 1.00 11.38 ? 422 LYS A C   1 
ATOM 1588 O O   . LYS A 1 422 ? 171.690 138.688 174.289 1.00 19.90 ? 422 LYS A O   1 
ATOM 1589 C CB  . LYS A 1 422 ? 172.599 136.426 171.804 1.00 8.56  ? 422 LYS A CB  1 
ATOM 1590 N N   . TYR A 1 443 ? 187.935 146.516 172.222 1.00 10.21 ? 443 TYR A N   1 
ATOM 1591 C CA  . TYR A 1 443 ? 188.508 147.850 172.363 1.00 8.85  ? 443 TYR A CA  1 
ATOM 1592 C C   . TYR A 1 443 ? 188.890 148.407 170.996 1.00 12.95 ? 443 TYR A C   1 
ATOM 1593 O O   . TYR A 1 443 ? 188.029 148.656 170.153 1.00 16.38 ? 443 TYR A O   1 
ATOM 1594 C CB  . TYR A 1 443 ? 189.730 147.819 173.286 1.00 7.19  ? 443 TYR A CB  1 
ATOM 1595 C CG  . TYR A 1 443 ? 189.398 147.677 174.757 1.00 12.49 ? 443 TYR A CG  1 
ATOM 1596 C CD1 . TYR A 1 443 ? 188.098 147.431 175.179 1.00 11.26 ? 443 TYR A CD1 1 
ATOM 1597 C CD2 . TYR A 1 443 ? 190.389 147.787 175.724 1.00 8.59  ? 443 TYR A CD2 1 
ATOM 1598 C CE1 . TYR A 1 443 ? 187.793 147.300 176.520 1.00 10.08 ? 443 TYR A CE1 1 
ATOM 1599 C CE2 . TYR A 1 443 ? 190.094 147.657 177.067 1.00 8.42  ? 443 TYR A CE2 1 
ATOM 1600 C CZ  . TYR A 1 443 ? 188.795 147.414 177.460 1.00 12.84 ? 443 TYR A CZ  1 
ATOM 1601 O OH  . TYR A 1 443 ? 188.494 147.285 178.796 1.00 15.00 ? 443 TYR A OH  1 
ATOM 1602 N N   . THR A 1 444 ? 190.187 148.606 170.785 1.00 8.30  ? 444 THR A N   1 
ATOM 1603 C CA  . THR A 1 444 ? 190.732 148.995 169.491 1.00 5.93  ? 444 THR A CA  1 
ATOM 1604 C C   . THR A 1 444 ? 191.746 147.942 169.067 1.00 10.06 ? 444 THR A C   1 
ATOM 1605 O O   . THR A 1 444 ? 192.850 147.882 169.618 1.00 10.08 ? 444 THR A O   1 
ATOM 1606 C CB  . THR A 1 444 ? 191.383 150.377 169.553 1.00 9.53  ? 444 THR A CB  1 
ATOM 1607 O OG1 . THR A 1 444 ? 190.467 151.316 170.129 1.00 15.89 ? 444 THR A OG1 1 
ATOM 1608 C CG2 . THR A 1 444 ? 191.769 150.847 168.159 1.00 6.23  ? 444 THR A CG2 1 
ATOM 1609 N N   . TYR A 1 445 ? 191.369 147.116 168.094 1.00 9.06  ? 445 TYR A N   1 
ATOM 1610 C CA  . TYR A 1 445 ? 192.203 146.013 167.640 1.00 7.05  ? 445 TYR A CA  1 
ATOM 1611 C C   . TYR A 1 445 ? 192.369 146.081 166.129 1.00 8.48  ? 445 TYR A C   1 
ATOM 1612 O O   . TYR A 1 445 ? 191.575 146.713 165.426 1.00 5.91  ? 445 TYR A O   1 
ATOM 1613 C CB  . TYR A 1 445 ? 191.622 144.643 168.045 1.00 7.94  ? 445 TYR A CB  1 
ATOM 1614 C CG  . TYR A 1 445 ? 190.108 144.563 168.059 1.00 6.80  ? 445 TYR A CG  1 
ATOM 1615 C CD1 . TYR A 1 445 ? 189.372 145.074 169.122 1.00 3.00  ? 445 TYR A CD1 1 
ATOM 1616 C CD2 . TYR A 1 445 ? 189.417 143.966 167.014 1.00 4.13  ? 445 TYR A CD2 1 
ATOM 1617 C CE1 . TYR A 1 445 ? 187.994 145.002 169.137 1.00 5.87  ? 445 TYR A CE1 1 
ATOM 1618 C CE2 . TYR A 1 445 ? 188.037 143.888 167.021 1.00 4.06  ? 445 TYR A CE2 1 
ATOM 1619 C CZ  . TYR A 1 445 ? 187.331 144.406 168.086 1.00 7.42  ? 445 TYR A CZ  1 
ATOM 1620 O OH  . TYR A 1 445 ? 185.957 144.330 168.098 1.00 6.97  ? 445 TYR A OH  1 
ATOM 1621 N N   . GLY A 1 446 ? 193.421 145.424 165.640 1.00 6.04  ? 446 GLY A N   1 
ATOM 1622 C CA  . GLY A 1 446 ? 193.748 145.458 164.226 1.00 6.31  ? 446 GLY A CA  1 
ATOM 1623 C C   . GLY A 1 446 ? 192.709 144.827 163.324 1.00 7.18  ? 446 GLY A C   1 
ATOM 1624 O O   . GLY A 1 446 ? 192.537 145.283 162.190 1.00 10.08 ? 446 GLY A O   1 
ATOM 1625 N N   . VAL A 1 447 ? 192.014 143.791 163.801 1.00 7.85  ? 447 VAL A N   1 
ATOM 1626 C CA  . VAL A 1 447 ? 191.060 143.072 162.957 1.00 8.25  ? 447 VAL A CA  1 
ATOM 1627 C C   . VAL A 1 447 ? 189.941 144.000 162.497 1.00 5.59  ? 447 VAL A C   1 
ATOM 1628 O O   . VAL A 1 447 ? 189.531 143.974 161.327 1.00 9.57  ? 447 VAL A O   1 
ATOM 1629 C CB  . VAL A 1 447 ? 190.510 141.843 163.706 1.00 4.95  ? 447 VAL A CB  1 
ATOM 1630 C CG1 . VAL A 1 447 ? 189.168 141.417 163.135 1.00 2.75  ? 447 VAL A CG1 1 
ATOM 1631 C CG2 . VAL A 1 447 ? 191.506 140.696 163.644 1.00 8.37  ? 447 VAL A CG2 1 
ATOM 1632 N N   . ARG A 1 448 ? 189.431 144.834 163.406 1.00 2.56  ? 448 ARG A N   1 
ATOM 1633 C CA  . ARG A 1 448 ? 188.365 145.763 163.044 1.00 6.57  ? 448 ARG A CA  1 
ATOM 1634 C C   . ARG A 1 448 ? 188.830 146.750 161.980 1.00 4.92  ? 448 ARG A C   1 
ATOM 1635 O O   . ARG A 1 448 ? 188.080 147.074 161.051 1.00 7.81  ? 448 ARG A O   1 
ATOM 1636 C CB  . ARG A 1 448 ? 187.871 146.501 164.288 1.00 5.15  ? 448 ARG A CB  1 
ATOM 1637 C CG  . ARG A 1 448 ? 186.430 146.965 164.193 1.00 4.62  ? 448 ARG A CG  1 
ATOM 1638 C CD  . ARG A 1 448 ? 185.840 147.264 165.569 1.00 6.18  ? 448 ARG A CD  1 
ATOM 1639 N NE  . ARG A 1 448 ? 184.614 148.059 165.526 1.00 11.83 ? 448 ARG A NE  1 
ATOM 1640 C CZ  . ARG A 1 448 ? 183.543 147.799 164.784 1.00 8.15  ? 448 ARG A CZ  1 
ATOM 1641 N NH1 . ARG A 1 448 ? 183.438 146.690 164.070 1.00 6.05  ? 448 ARG A NH1 1 
ATOM 1642 N NH2 . ARG A 1 448 ? 182.535 148.666 164.780 1.00 5.70  ? 448 ARG A NH2 1 
ATOM 1643 N N   . ALA A 1 449 ? 190.068 147.237 162.097 1.00 4.78  ? 449 ALA A N   1 
ATOM 1644 C CA  . ALA A 1 449 ? 190.618 148.127 161.080 1.00 3.20  ? 449 ALA A CA  1 
ATOM 1645 C C   . ALA A 1 449 ? 190.746 147.430 159.729 1.00 1.26  ? 449 ALA A C   1 
ATOM 1646 O O   . ALA A 1 449 ? 190.488 148.047 158.688 1.00 4.19  ? 449 ALA A O   1 
ATOM 1647 C CB  . ALA A 1 449 ? 191.973 148.668 161.536 1.00 4.29  ? 449 ALA A CB  1 
ATOM 1648 N N   . ILE A 1 450 ? 191.139 146.154 159.724 1.00 3.57  ? 450 ILE A N   1 
ATOM 1649 C CA  . ILE A 1 450 ? 191.216 145.399 158.476 1.00 3.98  ? 450 ILE A CA  1 
ATOM 1650 C C   . ILE A 1 450 ? 189.837 145.276 157.838 1.00 4.36  ? 450 ILE A C   1 
ATOM 1651 O O   . ILE A 1 450 ? 189.676 145.457 156.622 1.00 1.62  ? 450 ILE A O   1 
ATOM 1652 C CB  . ILE A 1 450 ? 191.848 144.018 158.726 1.00 4.42  ? 450 ILE A CB  1 
ATOM 1653 C CG1 . ILE A 1 450 ? 193.233 144.171 159.360 1.00 7.22  ? 450 ILE A CG1 1 
ATOM 1654 C CG2 . ILE A 1 450 ? 191.923 143.221 157.433 1.00 2.50  ? 450 ILE A CG2 1 
ATOM 1655 C CD1 . ILE A 1 450 ? 194.073 142.912 159.327 1.00 8.20  ? 450 ILE A CD1 1 
ATOM 1656 N N   . VAL A 1 451 ? 188.822 144.957 158.647 1.00 1.11  ? 451 VAL A N   1 
ATOM 1657 C CA  . VAL A 1 451 ? 187.463 144.863 158.120 1.00 0.96  ? 451 VAL A CA  1 
ATOM 1658 C C   . VAL A 1 451 ? 187.023 146.207 157.553 1.00 1.59  ? 451 VAL A C   1 
ATOM 1659 O O   . VAL A 1 451 ? 186.369 146.273 156.505 1.00 4.09  ? 451 VAL A O   1 
ATOM 1660 C CB  . VAL A 1 451 ? 186.495 144.358 159.207 1.00 2.89  ? 451 VAL A CB  1 
ATOM 1661 C CG1 . VAL A 1 451 ? 185.056 144.425 158.714 1.00 0.96  ? 451 VAL A CG1 1 
ATOM 1662 C CG2 . VAL A 1 451 ? 186.852 142.940 159.623 1.00 0.00  ? 451 VAL A CG2 1 
ATOM 1663 N N   . GLN A 1 452 ? 187.384 147.298 158.231 1.00 0.00  ? 452 GLN A N   1 
ATOM 1664 C CA  . GLN A 1 452 ? 187.038 148.629 157.741 1.00 0.00  ? 452 GLN A CA  1 
ATOM 1665 C C   . GLN A 1 452 ? 187.721 148.928 156.411 1.00 0.09  ? 452 GLN A C   1 
ATOM 1666 O O   . GLN A 1 452 ? 187.142 149.589 155.541 1.00 1.72  ? 452 GLN A O   1 
ATOM 1667 C CB  . GLN A 1 452 ? 187.406 149.682 158.787 1.00 0.00  ? 452 GLN A CB  1 
ATOM 1668 C CG  . GLN A 1 452 ? 187.175 151.110 158.339 1.00 0.37  ? 452 GLN A CG  1 
ATOM 1669 C CD  . GLN A 1 452 ? 185.703 151.455 158.238 1.00 2.27  ? 452 GLN A CD  1 
ATOM 1670 O OE1 . GLN A 1 452 ? 185.122 151.432 157.154 1.00 2.90  ? 452 GLN A OE1 1 
ATOM 1671 N NE2 . GLN A 1 452 ? 185.093 151.779 159.370 1.00 2.44  ? 452 GLN A NE2 1 
ATOM 1672 N N   . CYS A 1 453 ? 188.951 148.453 156.236 1.00 0.33  ? 453 CYS A N   1 
ATOM 1673 C CA  . CYS A 1 453 ? 189.697 148.717 155.012 1.00 1.08  ? 453 CYS A CA  1 
ATOM 1674 C C   . CYS A 1 453 ? 189.390 147.736 153.884 1.00 2.48  ? 453 CYS A C   1 
ATOM 1675 O O   . CYS A 1 453 ? 189.877 147.941 152.768 1.00 0.00  ? 453 CYS A O   1 
ATOM 1676 C CB  . CYS A 1 453 ? 191.199 148.701 155.306 1.00 0.00  ? 453 CYS A CB  1 
ATOM 1677 S SG  . CYS A 1 453 ? 191.767 150.074 156.323 1.00 10.49 ? 453 CYS A SG  1 
ATOM 1678 N N   . ILE A 1 454 ? 188.612 146.680 154.150 1.00 0.00  ? 454 ILE A N   1 
ATOM 1679 C CA  . ILE A 1 454 ? 188.369 145.649 153.132 1.00 1.82  ? 454 ILE A CA  1 
ATOM 1680 C C   . ILE A 1 454 ? 187.809 146.200 151.814 1.00 0.28  ? 454 ILE A C   1 
ATOM 1681 O O   . ILE A 1 454 ? 188.341 145.845 150.753 1.00 0.00  ? 454 ILE A O   1 
ATOM 1682 C CB  . ILE A 1 454 ? 187.503 144.521 153.721 1.00 1.91  ? 454 ILE A CB  1 
ATOM 1683 C CG1 . ILE A 1 454 ? 188.386 143.437 154.341 1.00 0.86  ? 454 ILE A CG1 1 
ATOM 1684 C CG2 . ILE A 1 454 ? 186.599 143.907 152.661 1.00 1.00  ? 454 ILE A CG2 1 
ATOM 1685 C CD1 . ILE A 1 454 ? 187.647 142.517 155.287 1.00 1.59  ? 454 ILE A CD1 1 
ATOM 1686 N N   . PRO A 1 455 ? 186.746 147.022 151.797 1.00 0.00  ? 455 PRO A N   1 
ATOM 1687 C CA  . PRO A 1 455 ? 186.255 147.522 150.494 1.00 0.00  ? 455 PRO A CA  1 
ATOM 1688 C C   . PRO A 1 455 ? 187.274 148.370 149.750 1.00 0.71  ? 455 PRO A C   1 
ATOM 1689 O O   . PRO A 1 455 ? 187.402 148.269 148.517 1.00 0.00  ? 455 PRO A O   1 
ATOM 1690 C CB  . PRO A 1 455 ? 185.008 148.333 150.874 1.00 0.00  ? 455 PRO A CB  1 
ATOM 1691 C CG  . PRO A 1 455 ? 184.608 147.819 152.214 1.00 0.00  ? 455 PRO A CG  1 
ATOM 1692 C CD  . PRO A 1 455 ? 185.885 147.476 152.904 1.00 0.00  ? 455 PRO A CD  1 
ATOM 1693 N N   . ALA A 1 456 ? 188.016 149.202 150.483 1.00 0.00  ? 456 ALA A N   1 
ATOM 1694 C CA  . ALA A 1 456 ? 189.097 149.962 149.872 1.00 0.00  ? 456 ALA A CA  1 
ATOM 1695 C C   . ALA A 1 456 ? 190.166 149.032 149.320 1.00 0.00  ? 456 ALA A C   1 
ATOM 1696 O O   . ALA A 1 456 ? 190.743 149.302 148.263 1.00 2.49  ? 456 ALA A O   1 
ATOM 1697 C CB  . ALA A 1 456 ? 189.696 150.933 150.885 1.00 0.00  ? 456 ALA A CB  1 
ATOM 1698 N N   . TRP A 1 457 ? 190.436 147.927 150.019 1.00 0.00  ? 457 TRP A N   1 
ATOM 1699 C CA  . TRP A 1 457 ? 191.383 146.937 149.517 1.00 0.00  ? 457 TRP A CA  1 
ATOM 1700 C C   . TRP A 1 457 ? 190.898 146.326 148.210 1.00 1.48  ? 457 TRP A C   1 
ATOM 1701 O O   . TRP A 1 457 ? 191.685 146.130 147.276 1.00 1.47  ? 457 TRP A O   1 
ATOM 1702 C CB  . TRP A 1 457 ? 191.609 145.853 150.571 1.00 0.00  ? 457 TRP A CB  1 
ATOM 1703 C CG  . TRP A 1 457 ? 192.223 144.604 150.028 1.00 0.33  ? 457 TRP A CG  1 
ATOM 1704 C CD1 . TRP A 1 457 ? 191.577 143.451 149.694 1.00 1.57  ? 457 TRP A CD1 1 
ATOM 1705 C CD2 . TRP A 1 457 ? 193.610 144.381 149.752 1.00 2.34  ? 457 TRP A CD2 1 
ATOM 1706 N NE1 . TRP A 1 457 ? 192.475 142.524 149.227 1.00 0.00  ? 457 TRP A NE1 1 
ATOM 1707 C CE2 . TRP A 1 457 ? 193.731 143.070 149.254 1.00 0.20  ? 457 TRP A CE2 1 
ATOM 1708 C CE3 . TRP A 1 457 ? 194.762 145.164 149.877 1.00 0.00  ? 457 TRP A CE3 1 
ATOM 1709 C CZ2 . TRP A 1 457 ? 194.957 142.523 148.881 1.00 4.54  ? 457 TRP A CZ2 1 
ATOM 1710 C CZ3 . TRP A 1 457 ? 195.978 144.619 149.508 1.00 1.20  ? 457 TRP A CZ3 1 
ATOM 1711 C CH2 . TRP A 1 457 ? 196.065 143.312 149.015 1.00 4.22  ? 457 TRP A CH2 1 
ATOM 1712 N N   . LEU A 1 458 ? 189.604 146.014 148.127 1.00 0.00  ? 458 LEU A N   1 
ATOM 1713 C CA  . LEU A 1 458 ? 189.057 145.450 146.898 1.00 0.00  ? 458 LEU A CA  1 
ATOM 1714 C C   . LEU A 1 458 ? 189.218 146.423 145.733 1.00 0.00  ? 458 LEU A C   1 
ATOM 1715 O O   . LEU A 1 458 ? 189.694 146.045 144.655 1.00 0.00  ? 458 LEU A O   1 
ATOM 1716 C CB  . LEU A 1 458 ? 187.588 145.076 147.104 1.00 0.00  ? 458 LEU A CB  1 
ATOM 1717 C CG  . LEU A 1 458 ? 187.312 144.017 148.178 1.00 2.86  ? 458 LEU A CG  1 
ATOM 1718 C CD1 . LEU A 1 458 ? 185.823 143.894 148.460 1.00 0.33  ? 458 LEU A CD1 1 
ATOM 1719 C CD2 . LEU A 1 458 ? 187.899 142.667 147.787 1.00 0.00  ? 458 LEU A CD2 1 
ATOM 1720 N N   . ARG A 1 459 ? 188.855 147.692 145.946 1.00 2.83  ? 459 ARG A N   1 
ATOM 1721 C CA  . ARG A 1 459 ? 189.006 148.687 144.883 1.00 1.76  ? 459 ARG A CA  1 
ATOM 1722 C C   . ARG A 1 459 ? 190.475 148.884 144.508 1.00 0.00  ? 459 ARG A C   1 
ATOM 1723 O O   . ARG A 1 459 ? 190.812 149.009 143.324 1.00 0.00  ? 459 ARG A O   1 
ATOM 1724 C CB  . ARG A 1 459 ? 188.378 150.018 145.305 1.00 0.00  ? 459 ARG A CB  1 
ATOM 1725 C CG  . ARG A 1 459 ? 186.872 150.136 145.057 1.00 0.00  ? 459 ARG A CG  1 
ATOM 1726 C CD  . ARG A 1 459 ? 186.494 149.954 143.588 1.00 0.00  ? 459 ARG A CD  1 
ATOM 1727 N NE  . ARG A 1 459 ? 186.956 151.047 142.742 1.00 0.00  ? 459 ARG A NE  1 
ATOM 1728 C CZ  . ARG A 1 459 ? 187.674 150.888 141.638 1.00 0.00  ? 459 ARG A CZ  1 
ATOM 1729 N NH1 . ARG A 1 459 ? 188.038 149.688 141.218 1.00 0.00  ? 459 ARG A NH1 1 
ATOM 1730 N NH2 . ARG A 1 459 ? 188.032 151.959 140.937 1.00 0.00  ? 459 ARG A NH2 1 
ATOM 1731 N N   . PHE A 1 460 ? 191.362 148.906 145.507 1.00 0.00  ? 460 PHE A N   1 
ATOM 1732 C CA  . PHE A 1 460 ? 192.789 149.108 145.271 1.00 2.17  ? 460 PHE A CA  1 
ATOM 1733 C C   . PHE A 1 460 ? 193.383 147.979 144.434 1.00 0.00  ? 460 PHE A C   1 
ATOM 1734 O O   . PHE A 1 460 ? 194.131 148.222 143.477 1.00 0.00  ? 460 PHE A O   1 
ATOM 1735 C CB  . PHE A 1 460 ? 193.502 149.229 146.623 1.00 0.58  ? 460 PHE A CB  1 
ATOM 1736 C CG  . PHE A 1 460 ? 195.002 149.237 146.540 1.00 0.29  ? 460 PHE A CG  1 
ATOM 1737 C CD1 . PHE A 1 460 ? 195.693 150.426 146.384 1.00 0.08  ? 460 PHE A CD1 1 
ATOM 1738 C CD2 . PHE A 1 460 ? 195.725 148.060 146.661 1.00 0.09  ? 460 PHE A CD2 1 
ATOM 1739 C CE1 . PHE A 1 460 ? 197.071 150.440 146.322 1.00 0.00  ? 460 PHE A CE1 1 
ATOM 1740 C CE2 . PHE A 1 460 ? 197.103 148.066 146.596 1.00 0.36  ? 460 PHE A CE2 1 
ATOM 1741 C CZ  . PHE A 1 460 ? 197.778 149.258 146.428 1.00 2.16  ? 460 PHE A CZ  1 
ATOM 1742 N N   . ILE A 1 461 ? 193.055 146.732 144.775 1.00 3.15  ? 461 ILE A N   1 
ATOM 1743 C CA  . ILE A 1 461 ? 193.626 145.616 144.030 1.00 0.00  ? 461 ILE A CA  1 
ATOM 1744 C C   . ILE A 1 461 ? 192.967 145.493 142.660 1.00 2.96  ? 461 ILE A C   1 
ATOM 1745 O O   . ILE A 1 461 ? 193.601 145.037 141.701 1.00 0.00  ? 461 ILE A O   1 
ATOM 1746 C CB  . ILE A 1 461 ? 193.539 144.315 144.854 1.00 2.70  ? 461 ILE A CB  1 
ATOM 1747 C CG1 . ILE A 1 461 ? 194.726 143.404 144.535 1.00 2.16  ? 461 ILE A CG1 1 
ATOM 1748 C CG2 . ILE A 1 461 ? 192.228 143.595 144.624 1.00 0.55  ? 461 ILE A CG2 1 
ATOM 1749 C CD1 . ILE A 1 461 ? 196.000 143.786 145.261 1.00 3.74  ? 461 ILE A CD1 1 
ATOM 1750 N N   . GLN A 1 462 ? 191.712 145.937 142.525 1.00 4.27  ? 462 GLN A N   1 
ATOM 1751 C CA  . GLN A 1 462 ? 191.113 146.038 141.198 1.00 0.91  ? 462 GLN A CA  1 
ATOM 1752 C C   . GLN A 1 462 ? 191.866 147.042 140.334 1.00 0.00  ? 462 GLN A C   1 
ATOM 1753 O O   . GLN A 1 462 ? 192.109 146.796 139.146 1.00 0.00  ? 462 GLN A O   1 
ATOM 1754 C CB  . GLN A 1 462 ? 189.640 146.432 141.312 1.00 0.00  ? 462 GLN A CB  1 
ATOM 1755 C CG  . GLN A 1 462 ? 188.675 145.265 141.441 1.00 0.21  ? 462 GLN A CG  1 
ATOM 1756 C CD  . GLN A 1 462 ? 187.224 145.709 141.440 1.00 0.12  ? 462 GLN A CD  1 
ATOM 1757 O OE1 . GLN A 1 462 ? 186.929 146.903 141.440 1.00 1.87  ? 462 GLN A OE1 1 
ATOM 1758 N NE2 . GLN A 1 462 ? 186.309 144.749 141.437 1.00 0.00  ? 462 GLN A NE2 1 
ATOM 1759 N N   . CYS A 1 463 ? 192.237 148.184 140.914 1.00 3.13  ? 463 CYS A N   1 
ATOM 1760 C CA  . CYS A 1 463 ? 193.004 149.179 140.170 1.00 0.70  ? 463 CYS A CA  1 
ATOM 1761 C C   . CYS A 1 463 ? 194.379 148.643 139.787 1.00 0.00  ? 463 CYS A C   1 
ATOM 1762 O O   . CYS A 1 463 ? 194.870 148.907 138.682 1.00 0.00  ? 463 CYS A O   1 
ATOM 1763 C CB  . CYS A 1 463 ? 193.131 150.463 140.989 1.00 0.61  ? 463 CYS A CB  1 
ATOM 1764 S SG  . CYS A 1 463 ? 191.602 151.425 141.109 1.00 3.37  ? 463 CYS A SG  1 
ATOM 1765 N N   . LEU A 1 464 ? 195.014 147.890 140.688 1.00 3.81  ? 464 LEU A N   1 
ATOM 1766 C CA  . LEU A 1 464 ? 196.296 147.269 140.362 1.00 3.69  ? 464 LEU A CA  1 
ATOM 1767 C C   . LEU A 1 464 ? 196.154 146.274 139.215 1.00 2.45  ? 464 LEU A C   1 
ATOM 1768 O O   . LEU A 1 464 ? 197.006 146.218 138.319 1.00 7.61  ? 464 LEU A O   1 
ATOM 1769 C CB  . LEU A 1 464 ? 196.879 146.580 141.595 1.00 1.75  ? 464 LEU A CB  1 
ATOM 1770 C CG  . LEU A 1 464 ? 197.447 147.479 142.694 1.00 1.48  ? 464 LEU A CG  1 
ATOM 1771 C CD1 . LEU A 1 464 ? 198.446 146.712 143.541 1.00 4.66  ? 464 LEU A CD1 1 
ATOM 1772 C CD2 . LEU A 1 464 ? 198.088 148.722 142.102 1.00 2.29  ? 464 LEU A CD2 1 
ATOM 1773 N N   . ARG A 1 465 ? 195.082 145.478 139.225 1.00 1.78  ? 465 ARG A N   1 
ATOM 1774 C CA  . ARG A 1 465 ? 194.845 144.536 138.135 1.00 2.72  ? 465 ARG A CA  1 
ATOM 1775 C C   . ARG A 1 465 ? 194.600 145.264 136.817 1.00 4.82  ? 465 ARG A C   1 
ATOM 1776 O O   . ARG A 1 465 ? 195.085 144.837 135.761 1.00 6.86  ? 465 ARG A O   1 
ATOM 1777 C CB  . ARG A 1 465 ? 193.665 143.627 138.484 1.00 3.46  ? 465 ARG A CB  1 
ATOM 1778 C CG  . ARG A 1 465 ? 193.060 142.901 137.300 1.00 5.37  ? 465 ARG A CG  1 
ATOM 1779 C CD  . ARG A 1 465 ? 193.765 141.583 137.046 1.00 4.27  ? 465 ARG A CD  1 
ATOM 1780 N NE  . ARG A 1 465 ? 193.383 141.000 135.766 1.00 7.01  ? 465 ARG A NE  1 
ATOM 1781 C CZ  . ARG A 1 465 ? 193.044 139.731 135.593 1.00 1.80  ? 465 ARG A CZ  1 
ATOM 1782 N NH1 . ARG A 1 465 ? 193.024 138.877 136.601 1.00 5.48  ? 465 ARG A NH1 1 
ATOM 1783 N NH2 . ARG A 1 465 ? 192.717 139.308 134.376 1.00 3.65  ? 465 ARG A NH2 1 
ATOM 1784 N N   . ARG A 1 466 ? 193.845 146.365 136.857 1.00 5.47  ? 466 ARG A N   1 
ATOM 1785 C CA  . ARG A 1 466 ? 193.611 147.143 135.643 1.00 0.00  ? 466 ARG A CA  1 
ATOM 1786 C C   . ARG A 1 466 ? 194.907 147.738 135.111 1.00 2.39  ? 466 ARG A C   1 
ATOM 1787 O O   . ARG A 1 466 ? 195.118 147.794 133.894 1.00 7.10  ? 466 ARG A O   1 
ATOM 1788 C CB  . ARG A 1 466 ? 192.587 148.245 135.906 1.00 0.00  ? 466 ARG A CB  1 
ATOM 1789 C CG  . ARG A 1 466 ? 191.149 147.768 135.949 1.00 0.00  ? 466 ARG A CG  1 
ATOM 1790 C CD  . ARG A 1 466 ? 190.197 148.935 135.788 1.00 0.00  ? 466 ARG A CD  1 
ATOM 1791 N NE  . ARG A 1 466 ? 189.916 149.209 134.385 1.00 3.01  ? 466 ARG A NE  1 
ATOM 1792 C CZ  . ARG A 1 466 ? 189.324 150.307 133.939 1.00 1.72  ? 466 ARG A CZ  1 
ATOM 1793 N NH1 . ARG A 1 466 ? 188.927 151.262 134.764 1.00 0.00  ? 466 ARG A NH1 1 
ATOM 1794 N NH2 . ARG A 1 466 ? 189.121 150.450 132.633 1.00 0.00  ? 466 ARG A NH2 1 
ATOM 1795 N N   . TYR A 1 467 ? 195.779 148.207 136.006 1.00 3.80  ? 467 TYR A N   1 
ATOM 1796 C CA  . TYR A 1 467 ? 197.077 148.706 135.567 1.00 4.01  ? 467 TYR A CA  1 
ATOM 1797 C C   . TYR A 1 467 ? 197.911 147.594 134.944 1.00 6.93  ? 467 TYR A C   1 
ATOM 1798 O O   . TYR A 1 467 ? 198.598 147.812 133.941 1.00 6.74  ? 467 TYR A O   1 
ATOM 1799 C CB  . TYR A 1 467 ? 197.830 149.342 136.733 1.00 4.40  ? 467 TYR A CB  1 
ATOM 1800 C CG  . TYR A 1 467 ? 199.289 149.581 136.425 1.00 9.26  ? 467 TYR A CG  1 
ATOM 1801 C CD1 . TYR A 1 467 ? 199.677 150.592 135.557 1.00 7.11  ? 467 TYR A CD1 1 
ATOM 1802 C CD2 . TYR A 1 467 ? 200.279 148.793 136.998 1.00 7.09  ? 467 TYR A CD2 1 
ATOM 1803 C CE1 . TYR A 1 467 ? 201.007 150.812 135.267 1.00 4.74  ? 467 TYR A CE1 1 
ATOM 1804 C CE2 . TYR A 1 467 ? 201.614 149.007 136.714 1.00 4.38  ? 467 TYR A CE2 1 
ATOM 1805 C CZ  . TYR A 1 467 ? 201.972 150.019 135.849 1.00 5.63  ? 467 TYR A CZ  1 
ATOM 1806 O OH  . TYR A 1 467 ? 203.299 150.238 135.563 1.00 11.81 ? 467 TYR A OH  1 
ATOM 1807 N N   . ARG A 1 468 ? 197.890 146.337 135.380 1.00 6.74  ? 468 ARG A N   1 
ATOM 1808 C CA  . ARG A 1 468 ? 198.694 145.279 134.760 1.00 2.91  ? 468 ARG A CA  1 
ATOM 1809 C C   . ARG A 1 468 ? 198.020 144.807 133.515 1.00 8.28  ? 468 ARG A C   1 
ATOM 1810 O O   . ARG A 1 468 ? 198.664 144.094 132.730 1.00 9.13  ? 468 ARG A O   1 
ATOM 1811 C CB  . ARG A 1 468 ? 198.542 143.936 135.442 1.00 5.60  ? 468 ARG A CB  1 
ATOM 1812 C CG  . ARG A 1 468 ? 199.747 143.027 135.624 1.00 7.28  ? 468 ARG A CG  1 
ATOM 1813 C CD  . ARG A 1 468 ? 199.249 141.604 135.613 1.00 7.65  ? 468 ARG A CD  1 
ATOM 1814 N NE  . ARG A 1 468 ? 198.059 141.460 134.769 1.00 10.72 ? 468 ARG A NE  1 
ATOM 1815 C CZ  . ARG A 1 468 ? 197.682 140.308 134.243 1.00 13.34 ? 468 ARG A CZ  1 
ATOM 1816 N NH1 . ARG A 1 468 ? 198.595 139.423 133.912 1.00 9.85  ? 468 ARG A NH1 1 
ATOM 1817 N NH2 . ARG A 1 468 ? 196.404 140.023 134.081 1.00 12.23 ? 468 ARG A NH2 1 
ATOM 1818 N N   . ASP A 1 469 ? 196.730 145.073 133.360 1.00 6.47  ? 469 ASP A N   1 
ATOM 1819 C CA  . ASP A 1 469 ? 196.132 144.736 132.072 1.00 2.18  ? 469 ASP A CA  1 
ATOM 1820 C C   . ASP A 1 469 ? 196.404 145.800 131.011 1.00 5.33  ? 469 ASP A C   1 
ATOM 1821 O O   . ASP A 1 469 ? 196.615 145.467 129.840 1.00 11.32 ? 469 ASP A O   1 
ATOM 1822 C CB  . ASP A 1 469 ? 194.628 144.517 132.234 1.00 2.86  ? 469 ASP A CB  1 
ATOM 1823 C CG  . ASP A 1 469 ? 194.287 143.090 132.609 1.00 5.43  ? 469 ASP A CG  1 
ATOM 1824 O OD1 . ASP A 1 469 ? 195.139 142.203 132.400 1.00 8.93  ? 469 ASP A OD1 1 
ATOM 1825 O OD2 . ASP A 1 469 ? 193.170 142.855 133.116 1.00 7.12  ? 469 ASP A OD2 1 
ATOM 1826 N N   . THR A 1 470 ? 196.405 147.079 131.394 1.00 9.69  ? 470 THR A N   1 
ATOM 1827 C CA  . THR A 1 470 ? 196.518 148.168 130.431 1.00 5.72  ? 470 THR A CA  1 
ATOM 1828 C C   . THR A 1 470 ? 197.872 148.865 130.425 1.00 7.44  ? 470 THR A C   1 
ATOM 1829 O O   . THR A 1 470 ? 198.190 149.536 129.439 1.00 11.51 ? 470 THR A O   1 
ATOM 1830 C CB  . THR A 1 470 ? 195.431 149.224 130.687 1.00 7.73  ? 470 THR A CB  1 
ATOM 1831 O OG1 . THR A 1 470 ? 195.627 149.810 131.980 1.00 8.01  ? 470 THR A OG1 1 
ATOM 1832 C CG2 . THR A 1 470 ? 194.048 148.595 130.624 1.00 7.22  ? 470 THR A CG2 1 
ATOM 1833 N N   . LYS A 1 471 ? 198.666 148.726 131.488 1.00 5.17  ? 471 LYS A N   1 
ATOM 1834 C CA  . LYS A 1 471 ? 199.986 149.357 131.588 1.00 3.66  ? 471 LYS A CA  1 
ATOM 1835 C C   . LYS A 1 471 ? 199.907 150.870 131.390 1.00 9.08  ? 471 LYS A C   1 
ATOM 1836 O O   . LYS A 1 471 ? 200.739 151.470 130.707 1.00 13.34 ? 471 LYS A O   1 
ATOM 1837 C CB  . LYS A 1 471 ? 200.978 148.732 130.604 1.00 4.38  ? 471 LYS A CB  1 
ATOM 1838 C CG  . LYS A 1 471 ? 200.918 147.217 130.548 1.00 6.61  ? 471 LYS A CG  1 
ATOM 1839 C CD  . LYS A 1 471 ? 201.359 146.604 131.866 1.00 8.14  ? 471 LYS A CD  1 
ATOM 1840 C CE  . LYS A 1 471 ? 202.841 146.836 132.117 1.00 9.16  ? 471 LYS A CE  1 
ATOM 1841 N NZ  . LYS A 1 471 ? 203.254 146.364 133.467 1.00 8.91  ? 471 LYS A NZ  1 
ATOM 1842 N N   . ARG A 1 472 ? 198.898 151.492 131.993 1.00 4.91  ? 472 ARG A N   1 
ATOM 1843 C CA  . ARG A 1 472 ? 198.740 152.943 131.982 1.00 5.77  ? 472 ARG A CA  1 
ATOM 1844 C C   . ARG A 1 472 ? 198.779 153.430 133.424 1.00 10.21 ? 472 ARG A C   1 
ATOM 1845 O O   . ARG A 1 472 ? 197.886 153.111 134.215 1.00 12.05 ? 472 ARG A O   1 
ATOM 1846 C CB  . ARG A 1 472 ? 197.439 153.353 131.295 1.00 6.42  ? 472 ARG A CB  1 
ATOM 1847 C CG  . ARG A 1 472 ? 197.154 152.595 130.010 1.00 8.24  ? 472 ARG A CG  1 
ATOM 1848 C CD  . ARG A 1 472 ? 195.952 153.171 129.283 1.00 6.96  ? 472 ARG A CD  1 
ATOM 1849 N NE  . ARG A 1 472 ? 195.938 154.628 129.317 1.00 6.66  ? 472 ARG A NE  1 
ATOM 1850 C CZ  . ARG A 1 472 ? 194.877 155.356 129.636 1.00 10.47 ? 472 ARG A CZ  1 
ATOM 1851 N NH1 . ARG A 1 472 ? 193.730 154.792 129.972 1.00 10.51 ? 472 ARG A NH1 1 
ATOM 1852 N NH2 . ARG A 1 472 ? 194.970 156.682 129.619 1.00 9.86  ? 472 ARG A NH2 1 
ATOM 1853 N N   . ALA A 1 473 ? 199.820 154.194 133.766 1.00 7.37  ? 473 ALA A N   1 
ATOM 1854 C CA  . ALA A 1 473 ? 199.931 154.727 135.119 1.00 8.98  ? 473 ALA A CA  1 
ATOM 1855 C C   . ALA A 1 473 ? 198.758 155.643 135.443 1.00 9.79  ? 473 ALA A C   1 
ATOM 1856 O O   . ALA A 1 473 ? 198.198 155.584 136.545 1.00 9.01  ? 473 ALA A O   1 
ATOM 1857 C CB  . ALA A 1 473 ? 201.258 155.466 135.286 1.00 7.93  ? 473 ALA A CB  1 
ATOM 1858 N N   . PHE A 1 474 ? 198.373 156.497 134.500 1.00 5.40  ? 474 PHE A N   1 
ATOM 1859 C CA  . PHE A 1 474 ? 197.146 157.255 134.687 1.00 5.67  ? 474 PHE A CA  1 
ATOM 1860 C C   . PHE A 1 474 ? 195.991 156.569 133.970 1.00 8.32  ? 474 PHE A C   1 
ATOM 1861 O O   . PHE A 1 474 ? 196.145 156.132 132.825 1.00 13.08 ? 474 PHE A O   1 
ATOM 1862 C CB  . PHE A 1 474 ? 197.292 158.683 134.161 1.00 2.81  ? 474 PHE A CB  1 
ATOM 1863 C CG  . PHE A 1 474 ? 196.237 159.626 134.668 1.00 8.53  ? 474 PHE A CG  1 
ATOM 1864 C CD1 . PHE A 1 474 ? 196.406 160.294 135.868 1.00 7.95  ? 474 PHE A CD1 1 
ATOM 1865 C CD2 . PHE A 1 474 ? 195.073 159.837 133.949 1.00 6.39  ? 474 PHE A CD2 1 
ATOM 1866 C CE1 . PHE A 1 474 ? 195.435 161.157 136.342 1.00 7.61  ? 474 PHE A CE1 1 
ATOM 1867 C CE2 . PHE A 1 474 ? 194.099 160.699 134.418 1.00 5.53  ? 474 PHE A CE2 1 
ATOM 1868 C CZ  . PHE A 1 474 ? 194.281 161.359 135.615 1.00 6.69  ? 474 PHE A CZ  1 
ATOM 1869 N N   . PRO A 1 475 ? 194.821 156.459 134.608 1.00 7.23  ? 475 PRO A N   1 
ATOM 1870 C CA  . PRO A 1 475 ? 194.483 156.914 135.958 1.00 3.10  ? 475 PRO A CA  1 
ATOM 1871 C C   . PRO A 1 475 ? 194.519 155.807 137.007 1.00 4.97  ? 475 PRO A C   1 
ATOM 1872 O O   . PRO A 1 475 ? 194.184 156.047 138.162 1.00 8.14  ? 475 PRO A O   1 
ATOM 1873 C CB  . PRO A 1 475 ? 193.062 157.446 135.765 1.00 4.43  ? 475 PRO A CB  1 
ATOM 1874 C CG  . PRO A 1 475 ? 192.465 156.484 134.756 1.00 4.20  ? 475 PRO A CG  1 
ATOM 1875 C CD  . PRO A 1 475 ? 193.620 155.987 133.896 1.00 5.44  ? 475 PRO A CD  1 
ATOM 1876 N N   . HIS A 1 476 ? 194.919 154.590 136.632 1.00 2.68  ? 476 HIS A N   1 
ATOM 1877 C CA  . HIS A 1 476 ? 194.722 153.437 137.508 1.00 2.56  ? 476 HIS A CA  1 
ATOM 1878 C C   . HIS A 1 476 ? 195.591 153.513 138.760 1.00 5.52  ? 476 HIS A C   1 
ATOM 1879 O O   . HIS A 1 476 ? 195.125 153.197 139.861 1.00 7.18  ? 476 HIS A O   1 
ATOM 1880 C CB  . HIS A 1 476 ? 194.987 152.149 136.732 1.00 1.28  ? 476 HIS A CB  1 
ATOM 1881 C CG  . HIS A 1 476 ? 194.154 152.014 135.497 1.00 1.55  ? 476 HIS A CG  1 
ATOM 1882 N ND1 . HIS A 1 476 ? 192.786 152.178 135.502 1.00 2.89  ? 476 HIS A ND1 1 
ATOM 1883 C CD2 . HIS A 1 476 ? 194.495 151.742 134.215 1.00 5.09  ? 476 HIS A CD2 1 
ATOM 1884 C CE1 . HIS A 1 476 ? 192.319 152.009 134.278 1.00 0.00  ? 476 HIS A CE1 1 
ATOM 1885 N NE2 . HIS A 1 476 ? 193.335 151.743 133.478 1.00 3.79  ? 476 HIS A NE2 1 
ATOM 1886 N N   . LEU A 1 477 ? 196.852 153.927 138.618 1.00 6.86  ? 477 LEU A N   1 
ATOM 1887 C CA  . LEU A 1 477 ? 197.713 154.056 139.790 1.00 2.36  ? 477 LEU A CA  1 
ATOM 1888 C C   . LEU A 1 477 ? 197.299 155.233 140.665 1.00 4.04  ? 477 LEU A C   1 
ATOM 1889 O O   . LEU A 1 477 ? 197.394 155.155 141.896 1.00 7.05  ? 477 LEU A O   1 
ATOM 1890 C CB  . LEU A 1 477 ? 199.174 154.194 139.359 1.00 6.93  ? 477 LEU A CB  1 
ATOM 1891 C CG  . LEU A 1 477 ? 199.789 152.992 138.637 1.00 5.78  ? 477 LEU A CG  1 
ATOM 1892 C CD1 . LEU A 1 477 ? 201.306 153.037 138.717 1.00 4.42  ? 477 LEU A CD1 1 
ATOM 1893 C CD2 . LEU A 1 477 ? 199.265 151.683 139.201 1.00 4.43  ? 477 LEU A CD2 1 
ATOM 1894 N N   . VAL A 1 478 ? 196.834 156.323 140.054 1.00 1.96  ? 478 VAL A N   1 
ATOM 1895 C CA  . VAL A 1 478 ? 196.293 157.439 140.825 1.00 1.73  ? 478 VAL A CA  1 
ATOM 1896 C C   . VAL A 1 478 ? 195.050 157.002 141.593 1.00 2.14  ? 478 VAL A C   1 
ATOM 1897 O O   . VAL A 1 478 ? 194.859 157.367 142.761 1.00 5.38  ? 478 VAL A O   1 
ATOM 1898 C CB  . VAL A 1 478 ? 196.005 158.629 139.891 1.00 4.11  ? 478 VAL A CB  1 
ATOM 1899 C CG1 . VAL A 1 478 ? 195.764 159.894 140.692 1.00 1.11  ? 478 VAL A CG1 1 
ATOM 1900 C CG2 . VAL A 1 478 ? 197.163 158.821 138.932 1.00 5.39  ? 478 VAL A CG2 1 
ATOM 1901 N N   . ASN A 1 479 ? 194.189 156.209 140.952 1.00 1.03  ? 479 ASN A N   1 
ATOM 1902 C CA  . ASN A 1 479 ? 193.028 155.657 141.642 1.00 0.57  ? 479 ASN A CA  1 
ATOM 1903 C C   . ASN A 1 479 ? 193.452 154.757 142.799 1.00 0.00  ? 479 ASN A C   1 
ATOM 1904 O O   . ASN A 1 479 ? 192.842 154.785 143.875 1.00 0.57  ? 479 ASN A O   1 
ATOM 1905 C CB  . ASN A 1 479 ? 192.152 154.891 140.650 1.00 2.17  ? 479 ASN A CB  1 
ATOM 1906 C CG  . ASN A 1 479 ? 190.681 155.231 140.783 1.00 0.00  ? 479 ASN A CG  1 
ATOM 1907 O OD1 . ASN A 1 479 ? 190.271 155.898 141.729 1.00 0.00  ? 479 ASN A OD1 1 
ATOM 1908 N ND2 . ASN A 1 479 ? 189.878 154.761 139.837 1.00 0.00  ? 479 ASN A ND2 1 
ATOM 1909 N N   . ALA A 1 480 ? 194.501 153.954 142.597 1.00 2.17  ? 480 ALA A N   1 
ATOM 1910 C CA  . ALA A 1 480 ? 195.007 153.109 143.675 1.00 2.12  ? 480 ALA A CA  1 
ATOM 1911 C C   . ALA A 1 480 ? 195.511 153.946 144.846 1.00 1.75  ? 480 ALA A C   1 
ATOM 1912 O O   . ALA A 1 480 ? 195.273 153.604 146.009 1.00 2.95  ? 480 ALA A O   1 
ATOM 1913 C CB  . ALA A 1 480 ? 196.114 152.194 143.152 1.00 0.25  ? 480 ALA A CB  1 
ATOM 1914 N N   . GLY A 1 481 ? 196.213 155.043 144.561 1.00 1.86  ? 481 GLY A N   1 
ATOM 1915 C CA  . GLY A 1 481 ? 196.633 155.936 145.632 1.00 2.09  ? 481 GLY A CA  1 
ATOM 1916 C C   . GLY A 1 481 ? 195.457 156.548 146.373 1.00 3.70  ? 481 GLY A C   1 
ATOM 1917 O O   . GLY A 1 481 ? 195.482 156.688 147.603 1.00 4.50  ? 481 GLY A O   1 
ATOM 1918 N N   . LYS A 1 482 ? 194.409 156.917 145.632 1.00 0.00  ? 482 LYS A N   1 
ATOM 1919 C CA  . LYS A 1 482 ? 193.192 157.418 146.262 1.00 0.00  ? 482 LYS A CA  1 
ATOM 1920 C C   . LYS A 1 482 ? 192.601 156.381 147.210 1.00 1.29  ? 482 LYS A C   1 
ATOM 1921 O O   . LYS A 1 482 ? 192.177 156.711 148.323 1.00 0.70  ? 482 LYS A O   1 
ATOM 1922 C CB  . LYS A 1 482 ? 192.169 157.812 145.195 1.00 0.00  ? 482 LYS A CB  1 
ATOM 1923 C CG  . LYS A 1 482 ? 190.966 158.563 145.741 1.00 0.73  ? 482 LYS A CG  1 
ATOM 1924 C CD  . LYS A 1 482 ? 189.801 158.558 144.768 1.00 3.48  ? 482 LYS A CD  1 
ATOM 1925 C CE  . LYS A 1 482 ? 189.250 157.158 144.555 1.00 2.64  ? 482 LYS A CE  1 
ATOM 1926 N NZ  . LYS A 1 482 ? 188.175 157.140 143.529 1.00 0.00  ? 482 LYS A NZ  1 
ATOM 1927 N N   . TYR A 1 483 ? 192.571 155.116 146.784 1.00 0.00  ? 483 TYR A N   1 
ATOM 1928 C CA  . TYR A 1 483 ? 192.017 154.065 147.632 1.00 0.00  ? 483 TYR A CA  1 
ATOM 1929 C C   . TYR A 1 483 ? 192.974 153.633 148.739 1.00 2.93  ? 483 TYR A C   1 
ATOM 1930 O O   . TYR A 1 483 ? 192.560 152.905 149.645 1.00 2.59  ? 483 TYR A O   1 
ATOM 1931 C CB  . TYR A 1 483 ? 191.611 152.858 146.782 1.00 0.00  ? 483 TYR A CB  1 
ATOM 1932 C CG  . TYR A 1 483 ? 190.378 153.119 145.952 1.00 0.00  ? 483 TYR A CG  1 
ATOM 1933 C CD1 . TYR A 1 483 ? 189.166 153.422 146.557 1.00 0.00  ? 483 TYR A CD1 1 
ATOM 1934 C CD2 . TYR A 1 483 ? 190.429 153.088 144.565 1.00 0.00  ? 483 TYR A CD2 1 
ATOM 1935 C CE1 . TYR A 1 483 ? 188.039 153.675 145.808 1.00 0.00  ? 483 TYR A CE1 1 
ATOM 1936 C CE2 . TYR A 1 483 ? 189.306 153.341 143.807 1.00 0.00  ? 483 TYR A CE2 1 
ATOM 1937 C CZ  . TYR A 1 483 ? 188.113 153.635 144.434 1.00 0.00  ? 483 TYR A CZ  1 
ATOM 1938 O OH  . TYR A 1 483 ? 186.989 153.887 143.686 1.00 0.00  ? 483 TYR A OH  1 
ATOM 1939 N N   . SER A 1 484 ? 194.243 154.033 148.672 1.00 2.73  ? 484 SER A N   1 
ATOM 1940 C CA  . SER A 1 484 ? 195.183 153.780 149.759 1.00 1.36  ? 484 SER A CA  1 
ATOM 1941 C C   . SER A 1 484 ? 195.199 154.892 150.804 1.00 2.47  ? 484 SER A C   1 
ATOM 1942 O O   . SER A 1 484 ? 195.680 154.671 151.930 1.00 3.62  ? 484 SER A O   1 
ATOM 1943 C CB  . SER A 1 484 ? 196.596 153.584 149.196 1.00 1.91  ? 484 SER A CB  1 
ATOM 1944 O OG  . SER A 1 484 ? 197.249 154.826 149.011 1.00 9.73  ? 484 SER A OG  1 
ATOM 1945 N N   . THR A 1 485 ? 194.709 156.082 150.446 1.00 4.42  ? 485 THR A N   1 
ATOM 1946 C CA  . THR A 1 485 ? 194.591 157.152 151.435 1.00 0.50  ? 485 THR A CA  1 
ATOM 1947 C C   . THR A 1 485 ? 193.775 156.705 152.645 1.00 1.80  ? 485 THR A C   1 
ATOM 1948 O O   . THR A 1 485 ? 194.102 157.055 153.786 1.00 4.68  ? 485 THR A O   1 
ATOM 1949 C CB  . THR A 1 485 ? 193.963 158.399 150.812 1.00 1.05  ? 485 THR A CB  1 
ATOM 1950 O OG1 . THR A 1 485 ? 192.666 158.080 150.292 1.00 4.70  ? 485 THR A OG1 1 
ATOM 1951 C CG2 . THR A 1 485 ? 194.843 158.949 149.706 1.00 1.40  ? 485 THR A CG2 1 
ATOM 1952 N N   . THR A 1 486 ? 192.706 155.935 152.419 1.00 5.57  ? 486 THR A N   1 
ATOM 1953 C CA  . THR A 1 486 ? 191.909 155.447 153.540 1.00 4.52  ? 486 THR A CA  1 
ATOM 1954 C C   . THR A 1 486 ? 192.666 154.419 154.373 1.00 1.78  ? 486 THR A C   1 
ATOM 1955 O O   . THR A 1 486 ? 192.477 154.364 155.592 1.00 1.89  ? 486 THR A O   1 
ATOM 1956 C CB  . THR A 1 486 ? 190.578 154.870 153.050 1.00 3.28  ? 486 THR A CB  1 
ATOM 1957 O OG1 . THR A 1 486 ? 189.820 155.889 152.385 1.00 8.02  ? 486 THR A OG1 1 
ATOM 1958 C CG2 . THR A 1 486 ? 189.782 154.314 154.194 1.00 5.54  ? 486 THR A CG2 1 
ATOM 1959 N N   . PHE A 1 487 ? 193.521 153.603 153.746 1.00 5.72  ? 487 PHE A N   1 
ATOM 1960 C CA  . PHE A 1 487 ? 194.406 152.737 154.521 1.00 1.95  ? 487 PHE A CA  1 
ATOM 1961 C C   . PHE A 1 487 ? 195.248 153.561 155.481 1.00 4.40  ? 487 PHE A C   1 
ATOM 1962 O O   . PHE A 1 487 ? 195.320 153.265 156.681 1.00 2.54  ? 487 PHE A O   1 
ATOM 1963 C CB  . PHE A 1 487 ? 195.327 151.932 153.601 1.00 4.07  ? 487 PHE A CB  1 
ATOM 1964 C CG  . PHE A 1 487 ? 194.613 151.007 152.669 1.00 1.57  ? 487 PHE A CG  1 
ATOM 1965 C CD1 . PHE A 1 487 ? 193.375 150.484 152.993 1.00 2.76  ? 487 PHE A CD1 1 
ATOM 1966 C CD2 . PHE A 1 487 ? 195.190 150.654 151.462 1.00 3.01  ? 487 PHE A CD2 1 
ATOM 1967 C CE1 . PHE A 1 487 ? 192.729 149.632 152.129 1.00 6.05  ? 487 PHE A CE1 1 
ATOM 1968 C CE2 . PHE A 1 487 ? 194.546 149.804 150.592 1.00 1.26  ? 487 PHE A CE2 1 
ATOM 1969 C CZ  . PHE A 1 487 ? 193.316 149.294 150.926 1.00 5.80  ? 487 PHE A CZ  1 
ATOM 1970 N N   . PHE A 1 488 ? 195.893 154.608 154.961 1.00 8.44  ? 488 PHE A N   1 
ATOM 1971 C CA  . PHE A 1 488 ? 196.736 155.442 155.816 1.00 3.31  ? 488 PHE A CA  1 
ATOM 1972 C C   . PHE A 1 488 ? 195.923 156.097 156.929 1.00 2.91  ? 488 PHE A C   1 
ATOM 1973 O O   . PHE A 1 488 ? 196.351 156.126 158.091 1.00 5.39  ? 488 PHE A O   1 
ATOM 1974 C CB  . PHE A 1 488 ? 197.460 156.502 154.986 1.00 2.76  ? 488 PHE A CB  1 
ATOM 1975 C CG  . PHE A 1 488 ? 198.581 155.957 154.148 1.00 4.97  ? 488 PHE A CG  1 
ATOM 1976 C CD1 . PHE A 1 488 ? 199.823 155.710 154.708 1.00 7.28  ? 488 PHE A CD1 1 
ATOM 1977 C CD2 . PHE A 1 488 ? 198.399 155.701 152.800 1.00 2.99  ? 488 PHE A CD2 1 
ATOM 1978 C CE1 . PHE A 1 488 ? 200.859 155.210 153.941 1.00 6.97  ? 488 PHE A CE1 1 
ATOM 1979 C CE2 . PHE A 1 488 ? 199.429 155.201 152.027 1.00 6.31  ? 488 PHE A CE2 1 
ATOM 1980 C CZ  . PHE A 1 488 ? 200.661 154.956 152.598 1.00 3.79  ? 488 PHE A CZ  1 
ATOM 1981 N N   . MET A 1 489 ? 194.739 156.614 156.592 1.00 3.09  ? 489 MET A N   1 
ATOM 1982 C CA  . MET A 1 489 ? 193.913 157.303 157.578 1.00 2.66  ? 489 MET A CA  1 
ATOM 1983 C C   . MET A 1 489 ? 193.480 156.361 158.696 1.00 1.82  ? 489 MET A C   1 
ATOM 1984 O O   . MET A 1 489 ? 193.588 156.696 159.882 1.00 2.23  ? 489 MET A O   1 
ATOM 1985 C CB  . MET A 1 489 ? 192.695 157.924 156.894 1.00 4.91  ? 489 MET A CB  1 
ATOM 1986 C CG  . MET A 1 489 ? 192.208 159.208 157.538 1.00 3.06  ? 489 MET A CG  1 
ATOM 1987 S SD  . MET A 1 489 ? 190.529 159.651 157.053 1.00 8.14  ? 489 MET A SD  1 
ATOM 1988 C CE  . MET A 1 489 ? 189.696 158.083 157.247 1.00 3.34  ? 489 MET A CE  1 
ATOM 1989 N N   . VAL A 1 490 ? 192.994 155.170 158.334 1.00 0.72  ? 490 VAL A N   1 
ATOM 1990 C CA  . VAL A 1 490 ? 192.540 154.212 159.336 1.00 0.89  ? 490 VAL A CA  1 
ATOM 1991 C C   . VAL A 1 490 ? 193.706 153.741 160.195 1.00 4.76  ? 490 VAL A C   1 
ATOM 1992 O O   . VAL A 1 490 ? 193.577 153.605 161.419 1.00 1.84  ? 490 VAL A O   1 
ATOM 1993 C CB  . VAL A 1 490 ? 191.818 153.032 158.657 1.00 2.24  ? 490 VAL A CB  1 
ATOM 1994 C CG1 . VAL A 1 490 ? 191.648 151.873 159.626 1.00 0.52  ? 490 VAL A CG1 1 
ATOM 1995 C CG2 . VAL A 1 490 ? 190.470 153.478 158.114 1.00 3.34  ? 490 VAL A CG2 1 
ATOM 1996 N N   . THR A 1 491 ? 194.862 153.487 159.575 1.00 1.67  ? 491 THR A N   1 
ATOM 1997 C CA  . THR A 1 491 ? 196.020 153.047 160.343 1.00 2.20  ? 491 THR A CA  1 
ATOM 1998 C C   . THR A 1 491 ? 196.427 154.095 161.367 1.00 5.69  ? 491 THR A C   1 
ATOM 1999 O O   . THR A 1 491 ? 196.689 153.770 162.533 1.00 6.20  ? 491 THR A O   1 
ATOM 2000 C CB  . THR A 1 491 ? 197.185 152.734 159.405 1.00 2.23  ? 491 THR A CB  1 
ATOM 2001 O OG1 . THR A 1 491 ? 196.833 151.637 158.554 1.00 8.01  ? 491 THR A OG1 1 
ATOM 2002 C CG2 . THR A 1 491 ? 198.429 152.372 160.200 1.00 3.79  ? 491 THR A CG2 1 
ATOM 2003 N N   . PHE A 1 492 ? 196.462 155.365 160.962 1.00 5.94  ? 492 PHE A N   1 
ATOM 2004 C CA  . PHE A 1 492 ? 196.901 156.400 161.890 1.00 3.77  ? 492 PHE A CA  1 
ATOM 2005 C C   . PHE A 1 492 ? 195.859 156.658 162.973 1.00 2.99  ? 492 PHE A C   1 
ATOM 2006 O O   . PHE A 1 492 ? 196.215 156.928 164.126 1.00 10.30 ? 492 PHE A O   1 
ATOM 2007 C CB  . PHE A 1 492 ? 197.249 157.671 161.122 1.00 1.78  ? 492 PHE A CB  1 
ATOM 2008 C CG  . PHE A 1 492 ? 198.600 157.615 160.472 1.00 2.01  ? 492 PHE A CG  1 
ATOM 2009 C CD1 . PHE A 1 492 ? 199.716 157.257 161.209 1.00 6.36  ? 492 PHE A CD1 1 
ATOM 2010 C CD2 . PHE A 1 492 ? 198.753 157.880 159.124 1.00 2.87  ? 492 PHE A CD2 1 
ATOM 2011 C CE1 . PHE A 1 492 ? 200.963 157.189 160.619 1.00 8.02  ? 492 PHE A CE1 1 
ATOM 2012 C CE2 . PHE A 1 492 ? 199.998 157.808 158.529 1.00 3.37  ? 492 PHE A CE2 1 
ATOM 2013 C CZ  . PHE A 1 492 ? 201.103 157.464 159.277 1.00 5.04  ? 492 PHE A CZ  1 
ATOM 2014 N N   . ALA A 1 493 ? 194.570 156.552 162.636 1.00 2.53  ? 493 ALA A N   1 
ATOM 2015 C CA  . ALA A 1 493 ? 193.537 156.680 163.660 1.00 2.31  ? 493 ALA A CA  1 
ATOM 2016 C C   . ALA A 1 493 ? 193.646 155.568 164.699 1.00 7.37  ? 493 ALA A C   1 
ATOM 2017 O O   . ALA A 1 493 ? 193.541 155.821 165.908 1.00 5.01  ? 493 ALA A O   1 
ATOM 2018 C CB  . ALA A 1 493 ? 192.153 156.681 163.014 1.00 2.24  ? 493 ALA A CB  1 
ATOM 2019 N N   . ALA A 1 494 ? 193.865 154.329 164.248 1.00 5.19  ? 494 ALA A N   1 
ATOM 2020 C CA  . ALA A 1 494 ? 194.012 153.218 165.183 1.00 0.58  ? 494 ALA A CA  1 
ATOM 2021 C C   . ALA A 1 494 ? 195.261 153.374 166.043 1.00 7.88  ? 494 ALA A C   1 
ATOM 2022 O O   . ALA A 1 494 ? 195.233 153.088 167.246 1.00 11.83 ? 494 ALA A O   1 
ATOM 2023 C CB  . ALA A 1 494 ? 194.040 151.892 164.425 1.00 2.63  ? 494 ALA A CB  1 
ATOM 2024 N N   . LEU A 1 495 ? 196.370 153.819 165.444 1.00 6.72  ? 495 LEU A N   1 
ATOM 2025 C CA  . LEU A 1 495 ? 197.591 154.019 166.219 1.00 2.84  ? 495 LEU A CA  1 
ATOM 2026 C C   . LEU A 1 495 ? 197.411 155.117 167.262 1.00 9.29  ? 495 LEU A C   1 
ATOM 2027 O O   . LEU A 1 495 ? 197.876 154.981 168.401 1.00 9.56  ? 495 LEU A O   1 
ATOM 2028 C CB  . LEU A 1 495 ? 198.758 154.341 165.287 1.00 6.15  ? 495 LEU A CB  1 
ATOM 2029 C CG  . LEU A 1 495 ? 199.384 153.136 164.581 1.00 5.62  ? 495 LEU A CG  1 
ATOM 2030 C CD1 . LEU A 1 495 ? 200.551 153.566 163.709 1.00 4.12  ? 495 LEU A CD1 1 
ATOM 2031 C CD2 . LEU A 1 495 ? 199.823 152.087 165.593 1.00 7.23  ? 495 LEU A CD2 1 
ATOM 2032 N N   . TYR A 1 496 ? 196.738 156.209 166.895 1.00 7.40  ? 496 TYR A N   1 
ATOM 2033 C CA  . TYR A 1 496 ? 196.444 157.272 167.844 1.00 3.41  ? 496 TYR A CA  1 
ATOM 2034 C C   . TYR A 1 496 ? 195.538 156.814 168.976 1.00 6.58  ? 496 TYR A C   1 
ATOM 2035 O O   . TYR A 1 496 ? 195.769 157.206 170.124 1.00 11.65 ? 496 TYR A O   1 
ATOM 2036 C CB  . TYR A 1 496 ? 195.810 158.464 167.122 1.00 8.72  ? 496 TYR A CB  1 
ATOM 2037 C CG  . TYR A 1 496 ? 195.158 159.471 168.043 1.00 11.58 ? 496 TYR A CG  1 
ATOM 2038 C CD1 . TYR A 1 496 ? 195.924 160.363 168.783 1.00 10.20 ? 496 TYR A CD1 1 
ATOM 2039 C CD2 . TYR A 1 496 ? 193.777 159.539 168.164 1.00 10.56 ? 496 TYR A CD2 1 
ATOM 2040 C CE1 . TYR A 1 496 ? 195.333 161.286 169.623 1.00 10.19 ? 496 TYR A CE1 1 
ATOM 2041 C CE2 . TYR A 1 496 ? 193.178 160.460 169.001 1.00 9.25  ? 496 TYR A CE2 1 
ATOM 2042 C CZ  . TYR A 1 496 ? 193.960 161.331 169.728 1.00 11.48 ? 496 TYR A CZ  1 
ATOM 2043 O OH  . TYR A 1 496 ? 193.368 162.249 170.562 1.00 14.44 ? 496 TYR A OH  1 
ATOM 2044 N N   . SER A 1 497 ? 194.520 156.001 168.690 1.00 6.80  ? 497 SER A N   1 
ATOM 2045 C CA  . SER A 1 497 ? 193.699 155.453 169.765 1.00 8.02  ? 497 SER A CA  1 
ATOM 2046 C C   . SER A 1 497 ? 194.462 154.493 170.667 1.00 10.46 ? 497 SER A C   1 
ATOM 2047 O O   . SER A 1 497 ? 194.240 154.497 171.882 1.00 9.24  ? 497 SER A O   1 
ATOM 2048 C CB  . SER A 1 497 ? 192.465 154.749 169.199 1.00 5.19  ? 497 SER A CB  1 
ATOM 2049 O OG  . SER A 1 497 ? 191.409 155.675 169.036 1.00 12.76 ? 497 SER A OG  1 
ATOM 2050 N N   . THR A 1 498 ? 195.349 153.668 170.109 1.00 6.05  ? 498 THR A N   1 
ATOM 2051 C CA  . THR A 1 498 ? 196.153 152.791 170.954 1.00 6.52  ? 498 THR A CA  1 
ATOM 2052 C C   . THR A 1 498 ? 197.082 153.591 171.864 1.00 10.80 ? 498 THR A C   1 
ATOM 2053 O O   . THR A 1 498 ? 197.129 153.350 173.079 1.00 13.22 ? 498 THR A O   1 
ATOM 2054 C CB  . THR A 1 498 ? 196.955 151.818 170.089 1.00 6.30  ? 498 THR A CB  1 
ATOM 2055 O OG1 . THR A 1 498 ? 196.092 150.776 169.617 1.00 10.84 ? 498 THR A OG1 1 
ATOM 2056 C CG2 . THR A 1 498 ? 198.093 151.198 170.888 1.00 7.41  ? 498 THR A CG2 1 
ATOM 2057 N N   . HIS A 1 499 ? 197.799 154.571 171.303 1.00 9.25  ? 499 HIS A N   1 
ATOM 2058 C CA  . HIS A 1 499 ? 198.719 155.405 172.068 1.00 6.47  ? 499 HIS A CA  1 
ATOM 2059 C C   . HIS A 1 499 ? 198.003 156.478 172.879 1.00 10.21 ? 499 HIS A C   1 
ATOM 2060 O O   . HIS A 1 499 ? 198.659 157.338 173.482 1.00 12.26 ? 499 HIS A O   1 
ATOM 2061 C CB  . HIS A 1 499 ? 199.756 156.038 171.140 1.00 7.32  ? 499 HIS A CB  1 
ATOM 2062 C CG  . HIS A 1 499 ? 200.762 155.067 170.606 1.00 5.52  ? 499 HIS A CG  1 
ATOM 2063 N ND1 . HIS A 1 499 ? 200.406 153.883 169.997 1.00 11.81 ? 499 HIS A ND1 1 
ATOM 2064 C CD2 . HIS A 1 499 ? 202.116 155.102 170.596 1.00 6.91  ? 499 HIS A CD2 1 
ATOM 2065 C CE1 . HIS A 1 499 ? 201.496 153.233 169.632 1.00 11.39 ? 499 HIS A CE1 1 
ATOM 2066 N NE2 . HIS A 1 499 ? 202.547 153.951 169.983 1.00 11.75 ? 499 HIS A NE2 1 
ATOM 2067 N N   . LYS A 1 500 ? 196.676 156.454 172.902 1.00 10.15 ? 500 LYS A N   1 
ATOM 2068 C CA  . LYS A 1 500 ? 195.923 157.303 173.814 1.00 8.73  ? 500 LYS A CA  1 
ATOM 2069 C C   . LYS A 1 500 ? 195.186 156.494 174.869 1.00 12.41 ? 500 LYS A C   1 
ATOM 2070 O O   . LYS A 1 500 ? 194.917 157.027 175.949 1.00 17.20 ? 500 LYS A O   1 
ATOM 2071 C CB  . LYS A 1 500 ? 194.934 158.179 173.021 1.00 10.86 ? 500 LYS A CB  1 
ATOM 2072 C CG  . LYS A 1 500 ? 194.133 159.168 173.856 1.00 7.59  ? 500 LYS A CG  1 
ATOM 2073 C CD  . LYS A 1 500 ? 193.223 160.019 172.989 1.00 7.80  ? 500 LYS A CD  1 
ATOM 2074 C CE  . LYS A 1 500 ? 192.409 160.986 173.833 1.00 11.56 ? 500 LYS A CE  1 
ATOM 2075 N NZ  . LYS A 1 500 ? 191.509 161.831 173.000 1.00 11.41 ? 500 LYS A NZ  1 
ATOM 2076 N N   . GLU A 1 501 ? 194.859 155.231 174.603 1.00 11.68 ? 501 GLU A N   1 
ATOM 2077 C CA  . GLU A 1 501 ? 194.368 154.313 175.618 1.00 9.57  ? 501 GLU A CA  1 
ATOM 2078 C C   . GLU A 1 501 ? 195.474 153.726 176.480 1.00 11.03 ? 501 GLU A C   1 
ATOM 2079 O O   . GLU A 1 501 ? 195.198 153.293 177.600 1.00 16.51 ? 501 GLU A O   1 
ATOM 2080 C CB  . GLU A 1 501 ? 193.580 153.167 174.968 1.00 9.72  ? 501 GLU A CB  1 
ATOM 2081 C CG  . GLU A 1 501 ? 194.431 151.976 174.548 1.00 9.03  ? 501 GLU A CG  1 
ATOM 2082 C CD  . GLU A 1 501 ? 193.611 150.849 173.950 1.00 10.90 ? 501 GLU A CD  1 
ATOM 2083 O OE1 . GLU A 1 501 ? 193.005 151.057 172.878 1.00 12.37 ? 501 GLU A OE1 1 
ATOM 2084 O OE2 . GLU A 1 501 ? 193.576 149.755 174.550 1.00 8.95  ? 501 GLU A OE2 1 
ATOM 2085 N N   . ARG A 1 502 ? 196.716 153.700 175.991 1.00 10.78 ? 502 ARG A N   1 
ATOM 2086 C CA  . ARG A 1 502 ? 197.819 153.211 176.809 1.00 8.03  ? 502 ARG A CA  1 
ATOM 2087 C C   . ARG A 1 502 ? 198.428 154.293 177.690 1.00 9.81  ? 502 ARG A C   1 
ATOM 2088 O O   . ARG A 1 502 ? 198.869 153.994 178.806 1.00 15.43 ? 502 ARG A O   1 
ATOM 2089 C CB  . ARG A 1 502 ? 198.910 152.598 175.929 1.00 9.36  ? 502 ARG A CB  1 
ATOM 2090 C CG  . ARG A 1 502 ? 198.965 151.079 176.000 1.00 9.52  ? 502 ARG A CG  1 
ATOM 2091 C CD  . ARG A 1 502 ? 200.286 150.534 175.480 1.00 10.51 ? 502 ARG A CD  1 
ATOM 2092 N NE  . ARG A 1 502 ? 200.611 151.033 174.149 1.00 14.15 ? 502 ARG A NE  1 
ATOM 2093 C CZ  . ARG A 1 502 ? 201.589 151.889 173.889 1.00 11.31 ? 502 ARG A CZ  1 
ATOM 2094 N NH1 . ARG A 1 502 ? 202.355 152.376 174.851 1.00 14.23 ? 502 ARG A NH1 1 
ATOM 2095 N NH2 . ARG A 1 502 ? 201.803 152.267 172.632 1.00 9.56  ? 502 ARG A NH2 1 
ATOM 2096 N N   . GLY A 1 503 ? 198.465 155.538 177.222 1.00 11.66 ? 503 GLY A N   1 
ATOM 2097 C CA  . GLY A 1 503 ? 199.032 156.616 178.009 1.00 8.33  ? 503 GLY A CA  1 
ATOM 2098 C C   . GLY A 1 503 ? 200.351 157.130 177.469 1.00 13.10 ? 503 GLY A C   1 
ATOM 2099 O O   . GLY A 1 503 ? 200.993 157.984 178.089 1.00 9.03  ? 503 GLY A O   1 
ATOM 2100 N N   . HIS A 1 504 ? 200.766 156.611 176.314 1.00 12.82 ? 504 HIS A N   1 
ATOM 2101 C CA  . HIS A 1 504 ? 202.028 156.997 175.693 1.00 9.19  ? 504 HIS A CA  1 
ATOM 2102 C C   . HIS A 1 504 ? 202.057 158.483 175.363 1.00 12.57 ? 504 HIS A C   1 
ATOM 2103 O O   . HIS A 1 504 ? 201.011 159.089 175.109 1.00 9.99  ? 504 HIS A O   1 
ATOM 2104 C CB  . HIS A 1 504 ? 202.269 156.173 174.427 1.00 9.77  ? 504 HIS A CB  1 
ATOM 2105 C CG  . HIS A 1 504 ? 203.693 155.754 174.238 1.00 12.09 ? 504 HIS A CG  1 
ATOM 2106 N ND1 . HIS A 1 504 ? 204.540 156.377 173.348 1.00 13.32 ? 504 HIS A ND1 1 
ATOM 2107 C CD2 . HIS A 1 504 ? 204.419 154.772 174.824 1.00 11.74 ? 504 HIS A CD2 1 
ATOM 2108 C CE1 . HIS A 1 504 ? 205.727 155.798 173.393 1.00 11.50 ? 504 HIS A CE1 1 
ATOM 2109 N NE2 . HIS A 1 504 ? 205.680 154.821 174.280 1.00 12.61 ? 504 HIS A NE2 1 
ATOM 2110 N N   . SER A 1 505 ? 203.249 159.080 175.373 1.00 11.30 ? 505 SER A N   1 
ATOM 2111 C CA  . SER A 1 505 ? 203.419 160.486 175.035 1.00 6.63  ? 505 SER A CA  1 
ATOM 2112 C C   . SER A 1 505 ? 203.541 160.732 173.537 1.00 11.17 ? 505 SER A C   1 
ATOM 2113 O O   . SER A 1 505 ? 203.551 161.893 173.115 1.00 14.01 ? 505 SER A O   1 
ATOM 2114 C CB  . SER A 1 505 ? 204.655 161.057 175.744 1.00 11.24 ? 505 SER A CB  1 
ATOM 2115 O OG  . SER A 1 505 ? 205.814 160.915 174.942 1.00 8.49  ? 505 SER A OG  1 
ATOM 2116 N N   . ASP A 1 506 ? 203.634 159.675 172.728 1.00 11.53 ? 506 ASP A N   1 
ATOM 2117 C CA  . ASP A 1 506 ? 203.703 159.811 171.278 1.00 9.81  ? 506 ASP A CA  1 
ATOM 2118 C C   . ASP A 1 506 ? 202.332 159.947 170.631 1.00 10.01 ? 506 ASP A C   1 
ATOM 2119 O O   . ASP A 1 506 ? 202.216 159.736 169.419 1.00 13.61 ? 506 ASP A O   1 
ATOM 2120 C CB  . ASP A 1 506 ? 204.439 158.612 170.675 1.00 9.18  ? 506 ASP A CB  1 
ATOM 2121 C CG  . ASP A 1 506 ? 205.845 158.957 170.227 1.00 11.74 ? 506 ASP A CG  1 
ATOM 2122 O OD1 . ASP A 1 506 ? 206.088 160.131 169.878 1.00 15.26 ? 506 ASP A OD1 1 
ATOM 2123 O OD2 . ASP A 1 506 ? 206.707 158.053 170.223 1.00 9.24  ? 506 ASP A OD2 1 
ATOM 2124 N N   . THR A 1 507 ? 201.297 160.279 171.405 1.00 11.93 ? 507 THR A N   1 
ATOM 2125 C CA  . THR A 1 507 ? 199.949 160.373 170.854 1.00 8.24  ? 507 THR A CA  1 
ATOM 2126 C C   . THR A 1 507 ? 199.820 161.551 169.895 1.00 11.35 ? 507 THR A C   1 
ATOM 2127 O O   . THR A 1 507 ? 199.074 161.487 168.912 1.00 17.57 ? 507 THR A O   1 
ATOM 2128 C CB  . THR A 1 507 ? 198.930 160.496 171.987 1.00 7.89  ? 507 THR A CB  1 
ATOM 2129 O OG1 . THR A 1 507 ? 198.998 159.333 172.819 1.00 15.72 ? 507 THR A OG1 1 
ATOM 2130 C CG2 . THR A 1 507 ? 197.525 160.612 171.422 1.00 11.49 ? 507 THR A CG2 1 
ATOM 2131 N N   . MET A 1 508 ? 200.535 162.643 170.175 1.00 11.35 ? 508 MET A N   1 
ATOM 2132 C CA  . MET A 1 508 ? 200.367 163.864 169.392 1.00 10.85 ? 508 MET A CA  1 
ATOM 2133 C C   . MET A 1 508 ? 200.806 163.669 167.945 1.00 8.88  ? 508 MET A C   1 
ATOM 2134 O O   . MET A 1 508 ? 200.166 164.176 167.018 1.00 17.62 ? 508 MET A O   1 
ATOM 2135 C CB  . MET A 1 508 ? 201.138 165.014 170.041 1.00 12.80 ? 508 MET A CB  1 
ATOM 2136 C CG  . MET A 1 508 ? 200.340 165.839 171.053 1.00 8.80  ? 508 MET A CG  1 
ATOM 2137 S SD  . MET A 1 508 ? 198.638 166.216 170.574 1.00 26.65 ? 508 MET A SD  1 
ATOM 2138 C CE  . MET A 1 508 ? 197.723 164.914 171.403 1.00 12.20 ? 508 MET A CE  1 
ATOM 2139 N N   . VAL A 1 509 ? 201.907 162.945 167.730 1.00 8.56  ? 509 VAL A N   1 
ATOM 2140 C CA  . VAL A 1 509 ? 202.391 162.733 166.366 1.00 7.56  ? 509 VAL A CA  1 
ATOM 2141 C C   . VAL A 1 509 ? 201.406 161.862 165.588 1.00 11.53 ? 509 VAL A C   1 
ATOM 2142 O O   . VAL A 1 509 ? 201.096 162.127 164.420 1.00 12.21 ? 509 VAL A O   1 
ATOM 2143 C CB  . VAL A 1 509 ? 203.816 162.146 166.377 1.00 6.74  ? 509 VAL A CB  1 
ATOM 2144 C CG1 . VAL A 1 509 ? 203.843 160.692 166.838 1.00 7.99  ? 509 VAL A CG1 1 
ATOM 2145 C CG2 . VAL A 1 509 ? 204.464 162.288 165.010 1.00 7.90  ? 509 VAL A CG2 1 
ATOM 2146 N N   . PHE A 1 510 ? 200.874 160.823 166.239 1.00 13.98 ? 510 PHE A N   1 
ATOM 2147 C CA  . PHE A 1 510 ? 199.887 159.973 165.585 1.00 7.15  ? 510 PHE A CA  1 
ATOM 2148 C C   . PHE A 1 510 ? 198.597 160.731 165.316 1.00 7.48  ? 510 PHE A C   1 
ATOM 2149 O O   . PHE A 1 510 ? 197.867 160.402 164.375 1.00 15.00 ? 510 PHE A O   1 
ATOM 2150 C CB  . PHE A 1 510 ? 199.613 158.733 166.437 1.00 6.76  ? 510 PHE A CB  1 
ATOM 2151 C CG  . PHE A 1 510 ? 200.665 157.668 166.315 1.00 7.51  ? 510 PHE A CG  1 
ATOM 2152 C CD1 . PHE A 1 510 ? 201.343 157.482 165.122 1.00 8.28  ? 510 PHE A CD1 1 
ATOM 2153 C CD2 . PHE A 1 510 ? 200.971 156.847 167.388 1.00 10.16 ? 510 PHE A CD2 1 
ATOM 2154 C CE1 . PHE A 1 510 ? 202.309 156.502 165.002 1.00 8.10  ? 510 PHE A CE1 1 
ATOM 2155 C CE2 . PHE A 1 510 ? 201.937 155.864 167.274 1.00 7.33  ? 510 PHE A CE2 1 
ATOM 2156 C CZ  . PHE A 1 510 ? 202.606 155.692 166.078 1.00 7.96  ? 510 PHE A CZ  1 
ATOM 2157 N N   . PHE A 1 511 ? 198.301 161.742 166.132 1.00 7.12  ? 511 PHE A N   1 
ATOM 2158 C CA  . PHE A 1 511 ? 197.142 162.593 165.899 1.00 7.84  ? 511 PHE A CA  1 
ATOM 2159 C C   . PHE A 1 511 ? 197.371 163.522 164.712 1.00 11.06 ? 511 PHE A C   1 
ATOM 2160 O O   . PHE A 1 511 ? 196.465 163.735 163.898 1.00 12.36 ? 511 PHE A O   1 
ATOM 2161 C CB  . PHE A 1 511 ? 196.836 163.390 167.169 1.00 8.05  ? 511 PHE A CB  1 
ATOM 2162 C CG  . PHE A 1 511 ? 195.644 164.294 167.058 1.00 8.79  ? 511 PHE A CG  1 
ATOM 2163 C CD1 . PHE A 1 511 ? 194.364 163.792 167.210 1.00 9.08  ? 511 PHE A CD1 1 
ATOM 2164 C CD2 . PHE A 1 511 ? 195.804 165.650 166.831 1.00 10.74 ? 511 PHE A CD2 1 
ATOM 2165 C CE1 . PHE A 1 511 ? 193.265 164.622 167.121 1.00 8.46  ? 511 PHE A CE1 1 
ATOM 2166 C CE2 . PHE A 1 511 ? 194.710 166.484 166.740 1.00 6.54  ? 511 PHE A CE2 1 
ATOM 2167 C CZ  . PHE A 1 511 ? 193.438 165.969 166.885 1.00 5.88  ? 511 PHE A CZ  1 
ATOM 2168 N N   . TYR A 1 512 ? 198.583 164.067 164.589 1.00 11.27 ? 512 TYR A N   1 
ATOM 2169 C CA  . TYR A 1 512 ? 198.865 165.008 163.508 1.00 7.53  ? 512 TYR A CA  1 
ATOM 2170 C C   . TYR A 1 512 ? 198.931 164.309 162.154 1.00 5.92  ? 512 TYR A C   1 
ATOM 2171 O O   . TYR A 1 512 ? 198.391 164.821 161.163 1.00 10.37 ? 512 TYR A O   1 
ATOM 2172 C CB  . TYR A 1 512 ? 200.158 165.769 163.795 1.00 9.45  ? 512 TYR A CB  1 
ATOM 2173 C CG  . TYR A 1 512 ? 199.999 166.833 164.858 1.00 8.11  ? 512 TYR A CG  1 
ATOM 2174 C CD1 . TYR A 1 512 ? 198.884 167.659 164.872 1.00 8.46  ? 512 TYR A CD1 1 
ATOM 2175 C CD2 . TYR A 1 512 ? 200.962 167.014 165.842 1.00 10.86 ? 512 TYR A CD2 1 
ATOM 2176 C CE1 . TYR A 1 512 ? 198.728 168.633 165.838 1.00 9.10  ? 512 TYR A CE1 1 
ATOM 2177 C CE2 . TYR A 1 512 ? 200.815 167.988 166.814 1.00 11.70 ? 512 TYR A CE2 1 
ATOM 2178 C CZ  . TYR A 1 512 ? 199.696 168.794 166.807 1.00 11.39 ? 512 TYR A CZ  1 
ATOM 2179 O OH  . TYR A 1 512 ? 199.543 169.765 167.770 1.00 14.97 ? 512 TYR A OH  1 
ATOM 2180 N N   . LEU A 1 513 ? 199.590 163.145 162.081 1.00 7.99  ? 513 LEU A N   1 
ATOM 2181 C CA  . LEU A 1 513 ? 199.524 162.375 160.839 1.00 8.12  ? 513 LEU A CA  1 
ATOM 2182 C C   . LEU A 1 513 ? 198.096 161.959 160.509 1.00 7.49  ? 513 LEU A C   1 
ATOM 2183 O O   . LEU A 1 513 ? 197.702 161.966 159.336 1.00 6.28  ? 513 LEU A O   1 
ATOM 2184 C CB  . LEU A 1 513 ? 200.455 161.157 160.858 1.00 7.19  ? 513 LEU A CB  1 
ATOM 2185 C CG  . LEU A 1 513 ? 201.977 161.331 160.740 1.00 7.16  ? 513 LEU A CG  1 
ATOM 2186 C CD1 . LEU A 1 513 ? 202.286 162.251 159.564 1.00 4.85  ? 513 LEU A CD1 1 
ATOM 2187 C CD2 . LEU A 1 513 ? 202.672 161.824 161.975 1.00 7.83  ? 513 LEU A CD2 1 
ATOM 2188 N N   . TRP A 1 514 ? 197.296 161.611 161.520 1.00 7.85  ? 514 TRP A N   1 
ATOM 2189 C CA  . TRP A 1 514 ? 195.903 161.284 161.231 1.00 3.61  ? 514 TRP A CA  1 
ATOM 2190 C C   . TRP A 1 514 ? 195.168 162.482 160.649 1.00 7.45  ? 514 TRP A C   1 
ATOM 2191 O O   . TRP A 1 514 ? 194.381 162.334 159.711 1.00 13.44 ? 514 TRP A O   1 
ATOM 2192 C CB  . TRP A 1 514 ? 195.169 160.787 162.474 1.00 3.66  ? 514 TRP A CB  1 
ATOM 2193 C CG  . TRP A 1 514 ? 193.700 160.666 162.194 1.00 3.42  ? 514 TRP A CG  1 
ATOM 2194 C CD1 . TRP A 1 514 ? 193.090 159.701 161.448 1.00 1.79  ? 514 TRP A CD1 1 
ATOM 2195 C CD2 . TRP A 1 514 ? 192.664 161.567 162.606 1.00 7.70  ? 514 TRP A CD2 1 
ATOM 2196 N NE1 . TRP A 1 514 ? 191.740 159.931 161.387 1.00 1.85  ? 514 TRP A NE1 1 
ATOM 2197 C CE2 . TRP A 1 514 ? 191.451 161.070 162.089 1.00 5.27  ? 514 TRP A CE2 1 
ATOM 2198 C CE3 . TRP A 1 514 ? 192.642 162.737 163.370 1.00 5.95  ? 514 TRP A CE3 1 
ATOM 2199 C CZ2 . TRP A 1 514 ? 190.230 161.702 162.313 1.00 7.05  ? 514 TRP A CZ2 1 
ATOM 2200 C CZ3 . TRP A 1 514 ? 191.429 163.361 163.591 1.00 5.50  ? 514 TRP A CZ3 1 
ATOM 2201 C CH2 . TRP A 1 514 ? 190.241 162.844 163.063 1.00 7.54  ? 514 TRP A CH2 1 
ATOM 2202 N N   . ILE A 1 515 ? 195.403 163.677 161.194 1.00 4.94  ? 515 ILE A N   1 
ATOM 2203 C CA  . ILE A 1 515 ? 194.706 164.866 160.703 1.00 5.53  ? 515 ILE A CA  1 
ATOM 2204 C C   . ILE A 1 515 ? 195.106 165.164 159.261 1.00 5.28  ? 515 ILE A C   1 
ATOM 2205 O O   . ILE A 1 515 ? 194.252 165.417 158.398 1.00 5.52  ? 515 ILE A O   1 
ATOM 2206 C CB  . ILE A 1 515 ? 194.976 166.068 161.626 1.00 6.29  ? 515 ILE A CB  1 
ATOM 2207 C CG1 . ILE A 1 515 ? 193.931 166.128 162.741 1.00 9.14  ? 515 ILE A CG1 1 
ATOM 2208 C CG2 . ILE A 1 515 ? 194.967 167.370 160.838 1.00 5.49  ? 515 ILE A CG2 1 
ATOM 2209 C CD1 . ILE A 1 515 ? 192.538 166.445 162.248 1.00 5.50  ? 515 ILE A CD1 1 
ATOM 2210 N N   . VAL A 1 516 ? 196.411 165.131 158.976 1.00 7.38  ? 516 VAL A N   1 
ATOM 2211 C CA  . VAL A 1 516 ? 196.852 165.478 157.628 1.00 3.25  ? 516 VAL A CA  1 
ATOM 2212 C C   . VAL A 1 516 ? 196.369 164.435 156.628 1.00 4.73  ? 516 VAL A C   1 
ATOM 2213 O O   . VAL A 1 516 ? 195.966 164.772 155.510 1.00 10.05 ? 516 VAL A O   1 
ATOM 2214 C CB  . VAL A 1 516 ? 198.382 165.669 157.569 1.00 5.28  ? 516 VAL A CB  1 
ATOM 2215 C CG1 . VAL A 1 516 ? 199.112 164.436 158.040 1.00 4.71  ? 516 VAL A CG1 1 
ATOM 2216 C CG2 . VAL A 1 516 ? 198.819 166.040 156.160 1.00 4.07  ? 516 VAL A CG2 1 
ATOM 2217 N N   . PHE A 1 517 ? 196.358 163.156 157.019 1.00 5.74  ? 517 PHE A N   1 
ATOM 2218 C CA  . PHE A 1 517 ? 195.887 162.132 156.097 1.00 5.17  ? 517 PHE A CA  1 
ATOM 2219 C C   . PHE A 1 517 ? 194.371 162.138 155.956 1.00 4.35  ? 517 PHE A C   1 
ATOM 2220 O O   . PHE A 1 517 ? 193.858 161.780 154.895 1.00 6.47  ? 517 PHE A O   1 
ATOM 2221 C CB  . PHE A 1 517 ? 196.394 160.759 156.534 1.00 5.21  ? 517 PHE A CB  1 
ATOM 2222 C CG  . PHE A 1 517 ? 197.716 160.396 155.927 1.00 5.89  ? 517 PHE A CG  1 
ATOM 2223 C CD1 . PHE A 1 517 ? 197.803 160.046 154.591 1.00 2.99  ? 517 PHE A CD1 1 
ATOM 2224 C CD2 . PHE A 1 517 ? 198.878 160.443 156.678 1.00 6.35  ? 517 PHE A CD2 1 
ATOM 2225 C CE1 . PHE A 1 517 ? 199.017 159.724 154.022 1.00 7.30  ? 517 PHE A CE1 1 
ATOM 2226 C CE2 . PHE A 1 517 ? 200.097 160.123 156.113 1.00 6.68  ? 517 PHE A CE2 1 
ATOM 2227 C CZ  . PHE A 1 517 ? 200.166 159.762 154.784 1.00 4.82  ? 517 PHE A CZ  1 
ATOM 2228 N N   . TYR A 1 518 ? 193.640 162.561 156.989 1.00 5.25  ? 518 TYR A N   1 
ATOM 2229 C CA  . TYR A 1 518 ? 192.205 162.769 156.845 1.00 3.39  ? 518 TYR A CA  1 
ATOM 2230 C C   . TYR A 1 518 ? 191.921 163.863 155.828 1.00 3.34  ? 518 TYR A C   1 
ATOM 2231 O O   . TYR A 1 518 ? 191.060 163.703 154.952 1.00 6.92  ? 518 TYR A O   1 
ATOM 2232 C CB  . TYR A 1 518 ? 191.595 163.107 158.210 1.00 3.12  ? 518 TYR A CB  1 
ATOM 2233 C CG  . TYR A 1 518 ? 190.234 163.771 158.164 1.00 4.57  ? 518 TYR A CG  1 
ATOM 2234 C CD1 . TYR A 1 518 ? 190.111 165.154 158.080 1.00 5.00  ? 518 TYR A CD1 1 
ATOM 2235 C CD2 . TYR A 1 518 ? 189.072 163.016 158.220 1.00 2.25  ? 518 TYR A CD2 1 
ATOM 2236 C CE1 . TYR A 1 518 ? 188.872 165.760 158.039 1.00 0.00  ? 518 TYR A CE1 1 
ATOM 2237 C CE2 . TYR A 1 518 ? 187.829 163.616 158.182 1.00 2.86  ? 518 TYR A CE2 1 
ATOM 2238 C CZ  . TYR A 1 518 ? 187.734 164.985 158.089 1.00 1.65  ? 518 TYR A CZ  1 
ATOM 2239 O OH  . TYR A 1 518 ? 186.494 165.578 158.051 1.00 0.03  ? 518 TYR A OH  1 
ATOM 2240 N N   . ILE A 1 519 ? 192.654 164.975 155.918 1.00 3.38  ? 519 ILE A N   1 
ATOM 2241 C CA  . ILE A 1 519 ? 192.489 166.053 154.946 1.00 4.53  ? 519 ILE A CA  1 
ATOM 2242 C C   . ILE A 1 519 ? 192.851 165.568 153.547 1.00 3.35  ? 519 ILE A C   1 
ATOM 2243 O O   . ILE A 1 519 ? 192.143 165.851 152.570 1.00 5.26  ? 519 ILE A O   1 
ATOM 2244 C CB  . ILE A 1 519 ? 193.327 167.276 155.361 1.00 5.28  ? 519 ILE A CB  1 
ATOM 2245 C CG1 . ILE A 1 519 ? 192.565 168.120 156.385 1.00 5.13  ? 519 ILE A CG1 1 
ATOM 2246 C CG2 . ILE A 1 519 ? 193.698 168.117 154.149 1.00 0.37  ? 519 ILE A CG2 1 
ATOM 2247 C CD1 . ILE A 1 519 ? 193.437 169.095 157.139 1.00 3.67  ? 519 ILE A CD1 1 
ATOM 2248 N N   . ILE A 1 520 ? 193.951 164.820 153.431 1.00 1.26  ? 520 ILE A N   1 
ATOM 2249 C CA  . ILE A 1 520 ? 194.395 164.330 152.129 1.00 3.05  ? 520 ILE A CA  1 
ATOM 2250 C C   . ILE A 1 520 ? 193.354 163.393 151.528 1.00 4.65  ? 520 ILE A C   1 
ATOM 2251 O O   . ILE A 1 520 ? 193.014 163.498 150.347 1.00 4.29  ? 520 ILE A O   1 
ATOM 2252 C CB  . ILE A 1 520 ? 195.768 163.646 152.252 1.00 6.56  ? 520 ILE A CB  1 
ATOM 2253 C CG1 . ILE A 1 520 ? 196.881 164.694 152.324 1.00 5.92  ? 520 ILE A CG1 1 
ATOM 2254 C CG2 . ILE A 1 520 ? 196.006 162.706 151.083 1.00 3.62  ? 520 ILE A CG2 1 
ATOM 2255 C CD1 . ILE A 1 520 ? 198.274 164.105 152.339 1.00 3.24  ? 520 ILE A CD1 1 
ATOM 2256 N N   . SER A 1 521 ? 192.826 162.469 152.334 1.00 4.85  ? 521 SER A N   1 
ATOM 2257 C CA  . SER A 1 521 ? 191.829 161.525 151.840 1.00 4.05  ? 521 SER A CA  1 
ATOM 2258 C C   . SER A 1 521 ? 190.558 162.243 151.404 1.00 3.10  ? 521 SER A C   1 
ATOM 2259 O O   . SER A 1 521 ? 190.011 161.963 150.329 1.00 0.16  ? 521 SER A O   1 
ATOM 2260 C CB  . SER A 1 521 ? 191.522 160.485 152.920 1.00 3.33  ? 521 SER A CB  1 
ATOM 2261 O OG  . SER A 1 521 ? 190.604 159.514 152.453 1.00 7.72  ? 521 SER A OG  1 
ATOM 2262 N N   . SER A 1 522 ? 190.080 163.185 152.223 1.00 1.21  ? 522 SER A N   1 
ATOM 2263 C CA  . SER A 1 522 ? 188.864 163.915 151.879 1.00 1.43  ? 522 SER A CA  1 
ATOM 2264 C C   . SER A 1 522 ? 189.038 164.697 150.582 1.00 2.90  ? 522 SER A C   1 
ATOM 2265 O O   . SER A 1 522 ? 188.202 164.608 149.674 1.00 6.23  ? 522 SER A O   1 
ATOM 2266 C CB  . SER A 1 522 ? 188.473 164.851 153.023 1.00 2.72  ? 522 SER A CB  1 
ATOM 2267 O OG  . SER A 1 522 ? 188.779 164.280 154.281 1.00 6.44  ? 522 SER A OG  1 
ATOM 2268 N N   . CYS A 1 523 ? 190.131 165.460 150.471 1.00 1.71  ? 523 CYS A N   1 
ATOM 2269 C CA  . CYS A 1 523 ? 190.358 166.252 149.266 1.00 3.99  ? 523 CYS A CA  1 
ATOM 2270 C C   . CYS A 1 523 ? 190.569 165.364 148.045 1.00 3.14  ? 523 CYS A C   1 
ATOM 2271 O O   . CYS A 1 523 ? 190.054 165.661 146.962 1.00 4.79  ? 523 CYS A O   1 
ATOM 2272 C CB  . CYS A 1 523 ? 191.552 167.184 149.469 1.00 5.88  ? 523 CYS A CB  1 
ATOM 2273 S SG  . CYS A 1 523 ? 191.217 168.597 150.549 1.00 13.16 ? 523 CYS A SG  1 
ATOM 2274 N N   . TYR A 1 524 ? 191.320 164.272 148.202 1.00 1.47  ? 524 TYR A N   1 
ATOM 2275 C CA  . TYR A 1 524 ? 191.575 163.345 147.105 1.00 0.11  ? 524 TYR A CA  1 
ATOM 2276 C C   . TYR A 1 524 ? 190.274 162.768 146.564 1.00 0.85  ? 524 TYR A C   1 
ATOM 2277 O O   . TYR A 1 524 ? 190.017 162.809 145.353 1.00 2.35  ? 524 TYR A O   1 
ATOM 2278 C CB  . TYR A 1 524 ? 192.498 162.234 147.609 1.00 2.41  ? 524 TYR A CB  1 
ATOM 2279 C CG  . TYR A 1 524 ? 193.420 161.590 146.596 1.00 2.68  ? 524 TYR A CG  1 
ATOM 2280 C CD1 . TYR A 1 524 ? 193.024 161.376 145.284 1.00 2.79  ? 524 TYR A CD1 1 
ATOM 2281 C CD2 . TYR A 1 524 ? 194.689 161.170 146.972 1.00 2.12  ? 524 TYR A CD2 1 
ATOM 2282 C CE1 . TYR A 1 524 ? 193.873 160.774 144.374 1.00 1.01  ? 524 TYR A CE1 1 
ATOM 2283 C CE2 . TYR A 1 524 ? 195.540 160.571 146.076 1.00 0.00  ? 524 TYR A CE2 1 
ATOM 2284 C CZ  . TYR A 1 524 ? 195.132 160.375 144.778 1.00 1.40  ? 524 TYR A CZ  1 
ATOM 2285 O OH  . TYR A 1 524 ? 195.989 159.776 143.889 1.00 5.32  ? 524 TYR A OH  1 
ATOM 2286 N N   . THR A 1 525 ? 189.428 162.239 147.453 1.00 0.00  ? 525 THR A N   1 
ATOM 2287 C CA  . THR A 1 525 ? 188.179 161.634 147.001 1.00 0.77  ? 525 THR A CA  1 
ATOM 2288 C C   . THR A 1 525 ? 187.227 162.678 146.430 1.00 1.79  ? 525 THR A C   1 
ATOM 2289 O O   . THR A 1 525 ? 186.539 162.411 145.440 1.00 3.37  ? 525 THR A O   1 
ATOM 2290 C CB  . THR A 1 525 ? 187.513 160.857 148.139 1.00 4.53  ? 525 THR A CB  1 
ATOM 2291 O OG1 . THR A 1 525 ? 187.468 161.663 149.322 1.00 4.28  ? 525 THR A OG1 1 
ATOM 2292 C CG2 . THR A 1 525 ? 188.279 159.577 148.425 1.00 0.00  ? 525 THR A CG2 1 
ATOM 2293 N N   . LEU A 1 526 ? 187.178 163.875 147.026 1.00 0.15  ? 526 LEU A N   1 
ATOM 2294 C CA  . LEU A 1 526 ? 186.303 164.922 146.502 1.00 0.61  ? 526 LEU A CA  1 
ATOM 2295 C C   . LEU A 1 526 ? 186.735 165.365 145.107 1.00 1.14  ? 526 LEU A C   1 
ATOM 2296 O O   . LEU A 1 526 ? 185.894 165.539 144.215 1.00 0.00  ? 526 LEU A O   1 
ATOM 2297 C CB  . LEU A 1 526 ? 186.282 166.110 147.463 1.00 0.62  ? 526 LEU A CB  1 
ATOM 2298 C CG  . LEU A 1 526 ? 185.520 167.369 147.044 1.00 0.98  ? 526 LEU A CG  1 
ATOM 2299 C CD1 . LEU A 1 526 ? 184.079 167.046 146.673 1.00 0.84  ? 526 LEU A CD1 1 
ATOM 2300 C CD2 . LEU A 1 526 ? 185.575 168.412 148.145 1.00 2.79  ? 526 LEU A CD2 1 
ATOM 2301 N N   . ILE A 1 527 ? 188.041 165.541 144.896 1.00 0.00  ? 527 ILE A N   1 
ATOM 2302 C CA  . ILE A 1 527 ? 188.530 165.972 143.592 1.00 0.00  ? 527 ILE A CA  1 
ATOM 2303 C C   . ILE A 1 527 ? 188.325 164.877 142.554 1.00 1.38  ? 527 ILE A C   1 
ATOM 2304 O O   . ILE A 1 527 ? 187.967 165.158 141.404 1.00 0.58  ? 527 ILE A O   1 
ATOM 2305 C CB  . ILE A 1 527 ? 190.003 166.408 143.693 1.00 0.13  ? 527 ILE A CB  1 
ATOM 2306 C CG1 . ILE A 1 527 ? 190.110 167.729 144.459 1.00 2.53  ? 527 ILE A CG1 1 
ATOM 2307 C CG2 . ILE A 1 527 ? 190.623 166.554 142.313 1.00 0.00  ? 527 ILE A CG2 1 
ATOM 2308 C CD1 . ILE A 1 527 ? 191.505 168.050 144.944 1.00 1.57  ? 527 ILE A CD1 1 
ATOM 2309 N N   . TRP A 1 528 ? 188.536 163.612 142.936 1.00 2.28  ? 528 TRP A N   1 
ATOM 2310 C CA  . TRP A 1 528 ? 188.268 162.518 142.008 1.00 0.37  ? 528 TRP A CA  1 
ATOM 2311 C C   . TRP A 1 528 ? 186.785 162.437 141.660 1.00 0.08  ? 528 TRP A C   1 
ATOM 2312 O O   . TRP A 1 528 ? 186.425 162.165 140.510 1.00 0.00  ? 528 TRP A O   1 
ATOM 2313 C CB  . TRP A 1 528 ? 188.761 161.191 142.587 1.00 0.59  ? 528 TRP A CB  1 
ATOM 2314 C CG  . TRP A 1 528 ? 188.854 160.102 141.558 1.00 1.83  ? 528 TRP A CG  1 
ATOM 2315 C CD1 . TRP A 1 528 ? 187.863 159.246 141.180 1.00 0.00  ? 528 TRP A CD1 1 
ATOM 2316 C CD2 . TRP A 1 528 ? 189.997 159.769 140.763 1.00 0.30  ? 528 TRP A CD2 1 
ATOM 2317 N NE1 . TRP A 1 528 ? 188.319 158.395 140.205 1.00 0.74  ? 528 TRP A NE1 1 
ATOM 2318 C CE2 . TRP A 1 528 ? 189.627 158.695 139.931 1.00 0.00  ? 528 TRP A CE2 1 
ATOM 2319 C CE3 . TRP A 1 528 ? 191.298 160.271 140.677 1.00 0.44  ? 528 TRP A CE3 1 
ATOM 2320 C CZ2 . TRP A 1 528 ? 190.510 158.116 139.023 1.00 0.00  ? 528 TRP A CZ2 1 
ATOM 2321 C CZ3 . TRP A 1 528 ? 192.173 159.694 139.776 1.00 2.19  ? 528 TRP A CZ3 1 
ATOM 2322 C CH2 . TRP A 1 528 ? 191.775 158.629 138.961 1.00 0.00  ? 528 TRP A CH2 1 
ATOM 2323 N N   . ASP A 1 529 ? 185.910 162.667 142.642 1.00 0.00  ? 529 ASP A N   1 
ATOM 2324 C CA  . ASP A 1 529 ? 184.476 162.696 142.374 1.00 0.00  ? 529 ASP A CA  1 
ATOM 2325 C C   . ASP A 1 529 ? 184.124 163.800 141.383 1.00 0.00  ? 529 ASP A C   1 
ATOM 2326 O O   . ASP A 1 529 ? 183.374 163.577 140.427 1.00 1.18  ? 529 ASP A O   1 
ATOM 2327 C CB  . ASP A 1 529 ? 183.703 162.899 143.678 1.00 0.00  ? 529 ASP A CB  1 
ATOM 2328 C CG  . ASP A 1 529 ? 183.537 161.620 144.474 1.00 0.62  ? 529 ASP A CG  1 
ATOM 2329 O OD1 . ASP A 1 529 ? 183.979 160.551 144.005 1.00 6.29  ? 529 ASP A OD1 1 
ATOM 2330 O OD2 . ASP A 1 529 ? 182.965 161.689 145.579 1.00 0.76  ? 529 ASP A OD2 1 
ATOM 2331 N N   . LEU A 1 530 ? 184.664 165.002 141.598 1.00 0.00  ? 530 LEU A N   1 
ATOM 2332 C CA  . LEU A 1 530 ? 184.240 166.154 140.808 1.00 0.00  ? 530 LEU A CA  1 
ATOM 2333 C C   . LEU A 1 530 ? 184.841 166.146 139.405 1.00 0.67  ? 530 LEU A C   1 
ATOM 2334 O O   . LEU A 1 530 ? 184.165 166.518 138.440 1.00 0.00  ? 530 LEU A O   1 
ATOM 2335 C CB  . LEU A 1 530 ? 184.604 167.448 141.536 1.00 0.00  ? 530 LEU A CB  1 
ATOM 2336 C CG  . LEU A 1 530 ? 183.863 167.727 142.848 1.00 1.59  ? 530 LEU A CG  1 
ATOM 2337 C CD1 . LEU A 1 530 ? 184.239 169.090 143.407 1.00 0.97  ? 530 LEU A CD1 1 
ATOM 2338 C CD2 . LEU A 1 530 ? 182.358 167.615 142.673 1.00 0.00  ? 530 LEU A CD2 1 
ATOM 2339 N N   . LYS A 1 531 ? 186.095 165.717 139.266 1.00 0.65  ? 531 LYS A N   1 
ATOM 2340 C CA  . LYS A 1 531 ? 186.813 165.840 138.003 1.00 0.00  ? 531 LYS A CA  1 
ATOM 2341 C C   . LYS A 1 531 ? 186.831 164.565 137.174 1.00 4.45  ? 531 LYS A C   1 
ATOM 2342 O O   . LYS A 1 531 ? 186.827 164.647 135.942 1.00 2.10  ? 531 LYS A O   1 
ATOM 2343 C CB  . LYS A 1 531 ? 188.258 166.283 138.255 1.00 1.01  ? 531 LYS A CB  1 
ATOM 2344 C CG  . LYS A 1 531 ? 188.494 167.768 138.060 1.00 5.85  ? 531 LYS A CG  1 
ATOM 2345 C CD  . LYS A 1 531 ? 188.845 168.085 136.614 1.00 1.73  ? 531 LYS A CD  1 
ATOM 2346 C CE  . LYS A 1 531 ? 188.864 169.581 136.369 1.00 4.88  ? 531 LYS A CE  1 
ATOM 2347 N NZ  . LYS A 1 531 ? 188.905 169.907 134.918 1.00 4.53  ? 531 LYS A NZ  1 
ATOM 2348 N N   . MET A 1 532 ? 186.869 163.391 137.801 1.00 4.96  ? 532 MET A N   1 
ATOM 2349 C CA  . MET A 1 532 ? 186.955 162.140 137.059 1.00 0.82  ? 532 MET A CA  1 
ATOM 2350 C C   . MET A 1 532 ? 185.625 161.398 136.990 1.00 1.34  ? 532 MET A C   1 
ATOM 2351 O O   . MET A 1 532 ? 185.190 161.019 135.901 1.00 6.19  ? 532 MET A O   1 
ATOM 2352 C CB  . MET A 1 532 ? 188.032 161.233 137.669 1.00 0.76  ? 532 MET A CB  1 
ATOM 2353 C CG  . MET A 1 532 ? 189.357 161.931 137.921 1.00 2.60  ? 532 MET A CG  1 
ATOM 2354 S SD  . MET A 1 532 ? 190.266 162.326 136.411 1.00 7.70  ? 532 MET A SD  1 
ATOM 2355 C CE  . MET A 1 532 ? 190.510 160.701 135.703 1.00 4.04  ? 532 MET A CE  1 
ATOM 2356 N N   . ASP A 1 533 ? 184.967 161.185 138.133 1.00 0.00  ? 533 ASP A N   1 
ATOM 2357 C CA  . ASP A 1 533 ? 183.722 160.421 138.141 1.00 0.00  ? 533 ASP A CA  1 
ATOM 2358 C C   . ASP A 1 533 ? 182.609 161.157 137.402 1.00 0.00  ? 533 ASP A C   1 
ATOM 2359 O O   . ASP A 1 533 ? 181.940 160.583 136.535 1.00 0.00  ? 533 ASP A O   1 
ATOM 2360 C CB  . ASP A 1 533 ? 183.297 160.119 139.580 1.00 0.00  ? 533 ASP A CB  1 
ATOM 2361 C CG  . ASP A 1 533 ? 184.179 159.079 140.249 1.00 0.00  ? 533 ASP A CG  1 
ATOM 2362 O OD1 . ASP A 1 533 ? 184.431 158.019 139.640 1.00 3.36  ? 533 ASP A OD1 1 
ATOM 2363 O OD2 . ASP A 1 533 ? 184.614 159.319 141.393 1.00 0.00  ? 533 ASP A OD2 1 
ATOM 2364 N N   . TRP A 1 534 ? 182.418 162.432 137.759 1.00 3.28  ? 534 TRP A N   1 
ATOM 2365 C CA  . TRP A 1 534 ? 181.334 163.241 137.145 1.00 0.00  ? 534 TRP A CA  1 
ATOM 2366 C C   . TRP A 1 534 ? 181.899 164.061 135.986 1.00 0.65  ? 534 TRP A C   1 
ATOM 2367 O O   . TRP A 1 534 ? 181.104 164.500 135.126 1.00 8.99  ? 534 TRP A O   1 
ATOM 2368 C CB  . TRP A 1 534 ? 180.699 164.155 138.201 1.00 0.00  ? 534 TRP A CB  1 
ATOM 2369 C CG  . TRP A 1 534 ? 180.111 163.434 139.386 1.00 1.18  ? 534 TRP A CG  1 
ATOM 2370 C CD1 . TRP A 1 534 ? 180.012 162.086 139.579 1.00 0.00  ? 534 TRP A CD1 1 
ATOM 2371 C CD2 . TRP A 1 534 ? 179.519 164.048 140.552 1.00 1.48  ? 534 TRP A CD2 1 
ATOM 2372 N NE1 . TRP A 1 534 ? 179.409 161.819 140.779 1.00 0.00  ? 534 TRP A NE1 1 
ATOM 2373 C CE2 . TRP A 1 534 ? 179.095 163.000 141.397 1.00 0.71  ? 534 TRP A CE2 1 
ATOM 2374 C CE3 . TRP A 1 534 ? 179.310 165.369 140.959 1.00 0.39  ? 534 TRP A CE3 1 
ATOM 2375 C CZ2 . TRP A 1 534 ? 178.476 163.241 142.622 1.00 0.64  ? 534 TRP A CZ2 1 
ATOM 2376 C CZ3 . TRP A 1 534 ? 178.698 165.604 142.170 1.00 0.00  ? 534 TRP A CZ3 1 
ATOM 2377 C CH2 . TRP A 1 534 ? 178.286 164.553 142.988 1.00 0.00  ? 534 TRP A CH2 1 
ATOM 2378 N N   . GLY A 1 535 ? 183.220 164.270 135.968 1.00 4.51  ? 535 GLY A N   1 
ATOM 2379 C CA  . GLY A 1 535 ? 183.865 165.007 134.864 1.00 1.05  ? 535 GLY A CA  1 
ATOM 2380 C C   . GLY A 1 535 ? 183.545 166.465 134.598 1.00 0.11  ? 535 GLY A C   1 
ATOM 2381 O O   . GLY A 1 535 ? 183.408 166.831 133.414 1.00 1.44  ? 535 GLY A O   1 
ATOM 2382 N N   . LEU A 1 536 ? 183.450 167.276 135.655 1.00 5.14  ? 536 LEU A N   1 
ATOM 2383 C CA  . LEU A 1 536 ? 182.885 168.649 135.567 1.00 1.97  ? 536 LEU A CA  1 
ATOM 2384 C C   . LEU A 1 536 ? 184.025 169.677 135.507 1.00 0.78  ? 536 LEU A C   1 
ATOM 2385 O O   . LEU A 1 536 ? 185.176 169.264 135.239 1.00 6.82  ? 536 LEU A O   1 
ATOM 2386 C CB  . LEU A 1 536 ? 181.958 168.901 136.754 1.00 1.94  ? 536 LEU A CB  1 
ATOM 2387 C CG  . LEU A 1 536 ? 180.727 167.993 136.839 1.00 0.94  ? 536 LEU A CG  1 
ATOM 2388 C CD1 . LEU A 1 536 ? 179.910 168.291 138.084 1.00 0.00  ? 536 LEU A CD1 1 
ATOM 2389 C CD2 . LEU A 1 536 ? 179.871 168.124 135.590 1.00 0.63  ? 536 LEU A CD2 1 
ATOM 2390 N N   . PHE A 1 537 ? 183.714 170.956 135.740 1.00 3.46  ? 537 PHE A N   1 
ATOM 2391 C CA  . PHE A 1 537 ? 184.721 172.015 135.702 1.00 4.26  ? 537 PHE A CA  1 
ATOM 2392 C C   . PHE A 1 537 ? 185.568 171.917 134.440 1.00 3.42  ? 537 PHE A C   1 
ATOM 2393 O O   . PHE A 1 537 ? 186.739 172.304 134.429 1.00 10.51 ? 537 PHE A O   1 
ATOM 2394 C CB  . PHE A 1 537 ? 185.607 171.989 136.951 1.00 2.20  ? 537 PHE A CB  1 
ATOM 2395 C CG  . PHE A 1 537 ? 184.882 172.349 138.212 1.00 4.59  ? 537 PHE A CG  1 
ATOM 2396 C CD1 . PHE A 1 537 ? 184.643 173.673 138.537 1.00 3.43  ? 537 PHE A CD1 1 
ATOM 2397 C CD2 . PHE A 1 537 ? 184.428 171.361 139.070 1.00 2.81  ? 537 PHE A CD2 1 
ATOM 2398 C CE1 . PHE A 1 537 ? 183.972 174.006 139.697 1.00 4.11  ? 537 PHE A CE1 1 
ATOM 2399 C CE2 . PHE A 1 537 ? 183.756 171.687 140.229 1.00 2.62  ? 537 PHE A CE2 1 
ATOM 2400 C CZ  . PHE A 1 537 ? 183.528 173.012 140.544 1.00 4.12  ? 537 PHE A CZ  1 
ATOM 2401 N N   . ASP A 1 538 ? 184.974 171.386 133.377 1.00 6.57  ? 538 ASP A N   1 
ATOM 2402 C CA  . ASP A 1 538 ? 185.675 171.176 132.123 1.00 7.94  ? 538 ASP A CA  1 
ATOM 2403 C C   . ASP A 1 538 ? 185.883 172.499 131.398 1.00 5.88  ? 538 ASP A C   1 
ATOM 2404 O O   . ASP A 1 538 ? 185.048 173.405 131.455 1.00 8.62  ? 538 ASP A O   1 
ATOM 2405 C CB  . ASP A 1 538 ? 184.894 170.205 131.237 1.00 3.77  ? 538 ASP A CB  1 
ATOM 2406 C CG  . ASP A 1 538 ? 185.784 169.451 130.275 1.00 9.42  ? 538 ASP A CG  1 
ATOM 2407 O OD1 . ASP A 1 538 ? 187.019 169.497 130.446 1.00 10.25 ? 538 ASP A OD1 1 
ATOM 2408 O OD2 . ASP A 1 538 ? 185.249 168.807 129.349 1.00 10.29 ? 538 ASP A OD2 1 
ATOM 2409 N N   . LYS A 1 539 ? 187.022 172.604 130.714 1.00 7.21  ? 539 LYS A N   1 
ATOM 2410 C CA  . LYS A 1 539 ? 187.328 173.792 129.930 1.00 5.82  ? 539 LYS A CA  1 
ATOM 2411 C C   . LYS A 1 539 ? 186.422 173.943 128.715 1.00 9.45  ? 539 LYS A C   1 
ATOM 2412 O O   . LYS A 1 539 ? 186.377 175.027 128.125 1.00 12.19 ? 539 LYS A O   1 
ATOM 2413 C CB  . LYS A 1 539 ? 188.791 173.759 129.487 1.00 6.73  ? 539 LYS A CB  1 
ATOM 2414 C CG  . LYS A 1 539 ? 189.142 172.566 128.619 1.00 5.19  ? 539 LYS A CG  1 
ATOM 2415 C CD  . LYS A 1 539 ? 190.644 172.432 128.445 1.00 7.42  ? 539 LYS A CD  1 
ATOM 2416 C CE  . LYS A 1 539 ? 191.005 172.144 126.998 1.00 6.39  ? 539 LYS A CE  1 
ATOM 2417 N NZ  . LYS A 1 539 ? 190.622 173.267 126.102 1.00 10.23 ? 539 LYS A NZ  1 
ATOM 2418 N N   . ASN A 1 540 ? 185.701 172.889 128.335 1.00 7.66  ? 540 ASN A N   1 
ATOM 2419 C CA  . ASN A 1 540 ? 184.800 172.928 127.192 1.00 4.87  ? 540 ASN A CA  1 
ATOM 2420 C C   . ASN A 1 540 ? 183.390 173.373 127.555 1.00 8.46  ? 540 ASN A C   1 
ATOM 2421 O O   . ASN A 1 540 ? 182.511 173.356 126.688 1.00 8.53  ? 540 ASN A O   1 
ATOM 2422 C CB  . ASN A 1 540 ? 184.740 171.552 126.519 1.00 6.30  ? 540 ASN A CB  1 
ATOM 2423 C CG  . ASN A 1 540 ? 186.083 171.114 125.968 1.00 10.59 ? 540 ASN A CG  1 
ATOM 2424 O OD1 . ASN A 1 540 ? 187.108 171.743 126.230 1.00 12.58 ? 540 ASN A OD1 1 
ATOM 2425 N ND2 . ASN A 1 540 ? 186.084 170.033 125.197 1.00 11.67 ? 540 ASN A ND2 1 
ATOM 2426 N N   . ALA A 1 541 ? 183.149 173.750 128.809 1.00 6.12  ? 541 ALA A N   1 
ATOM 2427 C CA  . ALA A 1 541 ? 181.840 174.244 129.217 1.00 5.35  ? 541 ALA A CA  1 
ATOM 2428 C C   . ALA A 1 541 ? 181.575 175.619 128.619 1.00 10.56 ? 541 ALA A C   1 
ATOM 2429 O O   . ALA A 1 541 ? 182.192 176.609 129.026 1.00 10.36 ? 541 ALA A O   1 
ATOM 2430 C CB  . ALA A 1 541 ? 181.738 174.297 130.741 1.00 5.85  ? 541 ALA A CB  1 
ATOM 2431 N N   . GLY A 1 542 ? 180.663 175.692 127.654 1.00 10.28 ? 542 GLY A N   1 
ATOM 2432 C CA  . GLY A 1 542 ? 180.371 176.949 126.997 1.00 10.41 ? 542 GLY A CA  1 
ATOM 2433 C C   . GLY A 1 542 ? 179.648 177.939 127.885 1.00 8.84  ? 542 GLY A C   1 
ATOM 2434 O O   . GLY A 1 542 ? 180.209 178.974 128.259 1.00 10.51 ? 542 GLY A O   1 
ATOM 2435 N N   . GLU A 1 543 ? 178.401 177.632 128.232 1.00 11.16 ? 543 GLU A N   1 
ATOM 2436 C CA  . GLU A 1 543 ? 177.591 178.493 129.081 1.00 6.80  ? 543 GLU A CA  1 
ATOM 2437 C C   . GLU A 1 543 ? 177.121 177.798 130.350 1.00 7.34  ? 543 GLU A C   1 
ATOM 2438 O O   . GLU A 1 543 ? 176.594 178.463 131.246 1.00 9.49  ? 543 GLU A O   1 
ATOM 2439 C CB  . GLU A 1 543 ? 176.385 179.023 128.298 1.00 8.67  ? 543 GLU A CB  1 
ATOM 2440 C CG  . GLU A 1 543 ? 176.519 180.473 127.854 1.00 9.16  ? 543 GLU A CG  1 
ATOM 2441 C CD  . GLU A 1 543 ? 177.692 180.697 126.918 1.00 12.88 ? 543 GLU A CD  1 
ATOM 2442 O OE1 . GLU A 1 543 ? 178.726 181.228 127.376 1.00 11.85 ? 543 GLU A OE1 1 
ATOM 2443 O OE2 . GLU A 1 543 ? 177.581 180.345 125.724 1.00 11.37 ? 543 GLU A OE2 1 
ATOM 2444 N N   . ASN A 1 544 ? 177.298 176.479 130.450 1.00 9.29  ? 544 ASN A N   1 
ATOM 2445 C CA  . ASN A 1 544 ? 177.058 175.754 131.697 1.00 5.45  ? 544 ASN A CA  1 
ATOM 2446 C C   . ASN A 1 544 ? 178.302 175.914 132.564 1.00 7.46  ? 544 ASN A C   1 
ATOM 2447 O O   . ASN A 1 544 ? 179.218 175.089 132.557 1.00 7.14  ? 544 ASN A O   1 
ATOM 2448 C CB  . ASN A 1 544 ? 176.741 174.288 131.424 1.00 5.40  ? 544 ASN A CB  1 
ATOM 2449 C CG  . ASN A 1 544 ? 175.723 174.104 130.317 1.00 8.81  ? 544 ASN A CG  1 
ATOM 2450 O OD1 . ASN A 1 544 ? 174.655 174.716 130.330 1.00 6.16  ? 544 ASN A OD1 1 
ATOM 2451 N ND2 . ASN A 1 544 ? 176.046 173.249 129.354 1.00 6.59  ? 544 ASN A ND2 1 
ATOM 2452 N N   . THR A 1 545 ? 178.330 177.013 133.315 1.00 6.54  ? 545 THR A N   1 
ATOM 2453 C CA  . THR A 1 545 ? 179.503 177.375 134.104 1.00 4.15  ? 545 THR A CA  1 
ATOM 2454 C C   . THR A 1 545 ? 179.851 176.285 135.107 1.00 4.47  ? 545 THR A C   1 
ATOM 2455 O O   . THR A 1 545 ? 178.988 175.815 135.854 1.00 6.46  ? 545 THR A O   1 
ATOM 2456 C CB  . THR A 1 545 ? 179.252 178.699 134.830 1.00 4.02  ? 545 THR A CB  1 
ATOM 2457 O OG1 . THR A 1 545 ? 178.108 178.572 135.683 1.00 6.88  ? 545 THR A OG1 1 
ATOM 2458 C CG2 . THR A 1 545 ? 179.011 179.818 133.831 1.00 3.73  ? 545 THR A CG2 1 
ATOM 2459 N N   . PHE A 1 546 ? 181.123 175.878 135.102 1.00 3.73  ? 546 PHE A N   1 
ATOM 2460 C CA  . PHE A 1 546 ? 181.711 174.890 136.004 1.00 3.30  ? 546 PHE A CA  1 
ATOM 2461 C C   . PHE A 1 546 ? 181.152 173.487 135.804 1.00 6.76  ? 546 PHE A C   1 
ATOM 2462 O O   . PHE A 1 546 ? 181.573 172.555 136.501 1.00 8.33  ? 546 PHE A O   1 
ATOM 2463 C CB  . PHE A 1 546 ? 181.557 175.303 137.472 1.00 5.82  ? 546 PHE A CB  1 
ATOM 2464 C CG  . PHE A 1 546 ? 182.008 176.707 137.751 1.00 7.55  ? 546 PHE A CG  1 
ATOM 2465 C CD1 . PHE A 1 546 ? 183.240 177.152 137.303 1.00 4.75  ? 546 PHE A CD1 1 
ATOM 2466 C CD2 . PHE A 1 546 ? 181.200 177.582 138.455 1.00 9.47  ? 546 PHE A CD2 1 
ATOM 2467 C CE1 . PHE A 1 546 ? 183.659 178.442 137.553 1.00 10.15 ? 546 PHE A CE1 1 
ATOM 2468 C CE2 . PHE A 1 546 ? 181.615 178.875 138.710 1.00 5.68  ? 546 PHE A CE2 1 
ATOM 2469 C CZ  . PHE A 1 546 ? 182.846 179.305 138.258 1.00 7.18  ? 546 PHE A CZ  1 
ATOM 2470 N N   . LEU A 1 547 ? 180.208 173.312 134.893 1.00 5.94  ? 547 LEU A N   1 
ATOM 2471 C CA  . LEU A 1 547 ? 179.707 171.999 134.495 1.00 2.59  ? 547 LEU A CA  1 
ATOM 2472 C C   . LEU A 1 547 ? 180.482 171.545 133.256 1.00 7.69  ? 547 LEU A C   1 
ATOM 2473 O O   . LEU A 1 547 ? 181.550 172.104 132.995 1.00 11.22 ? 547 LEU A O   1 
ATOM 2474 C CB  . LEU A 1 547 ? 178.194 172.056 134.324 1.00 3.80  ? 547 LEU A CB  1 
ATOM 2475 C CG  . LEU A 1 547 ? 177.430 172.842 135.391 1.00 2.08  ? 547 LEU A CG  1 
ATOM 2476 C CD1 . LEU A 1 547 ? 175.945 172.874 135.072 1.00 2.13  ? 547 LEU A CD1 1 
ATOM 2477 C CD2 . LEU A 1 547 ? 177.676 172.250 136.769 1.00 0.45  ? 547 LEU A CD2 1 
ATOM 2478 N N   . ARG A 1 548 ? 180.023 170.536 132.522 1.00 5.94  ? 548 ARG A N   1 
ATOM 2479 C CA  . ARG A 1 548 ? 180.623 170.147 131.256 1.00 2.15  ? 548 ARG A CA  1 
ATOM 2480 C C   . ARG A 1 548 ? 179.702 170.554 130.113 1.00 3.85  ? 548 ARG A C   1 
ATOM 2481 O O   . ARG A 1 548 ? 178.581 171.019 130.330 1.00 8.67  ? 548 ARG A O   1 
ATOM 2482 C CB  . ARG A 1 548 ? 180.925 168.645 131.243 1.00 7.44  ? 548 ARG A CB  1 
ATOM 2483 C CG  . ARG A 1 548 ? 179.715 167.790 131.542 1.00 2.32  ? 548 ARG A CG  1 
ATOM 2484 C CD  . ARG A 1 548 ? 180.088 166.318 131.672 1.00 2.86  ? 548 ARG A CD  1 
ATOM 2485 N NE  . ARG A 1 548 ? 179.346 165.609 132.714 1.00 3.82  ? 548 ARG A NE  1 
ATOM 2486 C CZ  . ARG A 1 548 ? 178.032 165.637 132.907 1.00 5.60  ? 548 ARG A CZ  1 
ATOM 2487 N NH1 . ARG A 1 548 ? 177.214 166.263 132.076 1.00 0.00  ? 548 ARG A NH1 1 
ATOM 2488 N NH2 . ARG A 1 548 ? 177.522 165.007 133.961 1.00 4.26  ? 548 ARG A NH2 1 
ATOM 2489 N N   . GLU A 1 549 ? 180.200 170.379 128.887 1.00 6.41  ? 549 GLU A N   1 
ATOM 2490 C CA  . GLU A 1 549 ? 179.495 170.886 127.711 1.00 8.58  ? 549 GLU A CA  1 
ATOM 2491 C C   . GLU A 1 549 ? 178.136 170.216 127.537 1.00 4.62  ? 549 GLU A C   1 
ATOM 2492 O O   . GLU A 1 549 ? 177.153 170.871 127.173 1.00 11.07 ? 549 GLU A O   1 
ATOM 2493 C CB  . GLU A 1 549 ? 180.358 170.701 126.461 1.00 10.23 ? 549 GLU A CB  1 
ATOM 2494 C CG  . GLU A 1 549 ? 180.845 169.280 126.232 1.00 6.84  ? 549 GLU A CG  1 
ATOM 2495 C CD  . GLU A 1 549 ? 181.096 168.983 124.768 1.00 9.38  ? 549 GLU A CD  1 
ATOM 2496 O OE1 . GLU A 1 549 ? 181.845 169.750 124.126 1.00 14.27 ? 549 GLU A OE1 1 
ATOM 2497 O OE2 . GLU A 1 549 ? 180.541 167.988 124.258 1.00 13.63 ? 549 GLU A OE2 1 
ATOM 2498 N N   . GLU A 1 550 ? 178.059 168.914 127.786 1.00 9.79  ? 550 GLU A N   1 
ATOM 2499 C CA  . GLU A 1 550 ? 176.802 168.199 127.627 1.00 7.78  ? 550 GLU A CA  1 
ATOM 2500 C C   . GLU A 1 550 ? 176.257 167.842 129.004 1.00 4.97  ? 550 GLU A C   1 
ATOM 2501 O O   . GLU A 1 550 ? 176.933 167.191 129.806 1.00 8.53  ? 550 GLU A O   1 
ATOM 2502 C CB  . GLU A 1 550 ? 177.025 166.951 126.758 1.00 9.40  ? 550 GLU A CB  1 
ATOM 2503 C CG  . GLU A 1 550 ? 175.798 166.203 126.169 1.00 7.57  ? 550 GLU A CG  1 
ATOM 2504 C CD  . GLU A 1 550 ? 174.733 165.713 127.146 1.00 11.42 ? 550 GLU A CD  1 
ATOM 2505 O OE1 . GLU A 1 550 ? 174.995 165.571 128.353 1.00 10.36 ? 550 GLU A OE1 1 
ATOM 2506 O OE2 . GLU A 1 550 ? 173.602 165.461 126.683 1.00 14.84 ? 550 GLU A OE2 1 
ATOM 2507 N N   . ILE A 1 551 ? 175.026 168.275 129.279 1.00 6.76  ? 551 ILE A N   1 
ATOM 2508 C CA  . ILE A 1 551 ? 174.311 167.848 130.478 1.00 2.03  ? 551 ILE A CA  1 
ATOM 2509 C C   . ILE A 1 551 ? 172.967 167.260 130.060 1.00 4.93  ? 551 ILE A C   1 
ATOM 2510 O O   . ILE A 1 551 ? 172.220 167.860 129.279 1.00 12.43 ? 551 ILE A O   1 
ATOM 2511 C CB  . ILE A 1 551 ? 174.150 168.994 131.500 1.00 8.06  ? 551 ILE A CB  1 
ATOM 2512 C CG1 . ILE A 1 551 ? 173.173 170.070 131.015 1.00 3.51  ? 551 ILE A CG1 1 
ATOM 2513 C CG2 . ILE A 1 551 ? 175.501 169.611 131.835 1.00 5.42  ? 551 ILE A CG2 1 
ATOM 2514 C CD1 . ILE A 1 551 ? 172.938 171.173 132.024 1.00 4.42  ? 551 ILE A CD1 1 
ATOM 2515 N N   . VAL A 1 552 ? 172.669 166.055 130.549 1.00 5.13  ? 552 VAL A N   1 
ATOM 2516 C CA  . VAL A 1 552 ? 171.426 165.388 130.180 1.00 1.95  ? 552 VAL A CA  1 
ATOM 2517 C C   . VAL A 1 552 ? 170.279 165.750 131.113 1.00 5.75  ? 552 VAL A C   1 
ATOM 2518 O O   . VAL A 1 552 ? 169.159 165.986 130.644 1.00 14.32 ? 552 VAL A O   1 
ATOM 2519 C CB  . VAL A 1 552 ? 171.618 163.863 130.156 1.00 4.63  ? 552 VAL A CB  1 
ATOM 2520 C CG1 . VAL A 1 552 ? 170.321 163.169 129.793 1.00 5.19  ? 552 VAL A CG1 1 
ATOM 2521 C CG2 . VAL A 1 552 ? 172.723 163.482 129.188 1.00 5.16  ? 552 VAL A CG2 1 
ATOM 2522 N N   . TYR A 1 553 ? 170.525 165.805 132.409 1.00 6.72  ? 553 TYR A N   1 
ATOM 2523 C CA  . TYR A 1 553 ? 169.476 166.128 133.363 1.00 3.36  ? 553 TYR A CA  1 
ATOM 2524 C C   . TYR A 1 553 ? 169.019 167.574 133.168 1.00 4.59  ? 553 TYR A C   1 
ATOM 2525 O O   . TYR A 1 553 ? 169.844 168.458 132.921 1.00 5.26  ? 553 TYR A O   1 
ATOM 2526 C CB  . TYR A 1 553 ? 169.975 165.906 134.785 1.00 1.35  ? 553 TYR A CB  1 
ATOM 2527 C CG  . TYR A 1 553 ? 170.447 164.487 135.006 1.00 0.69  ? 553 TYR A CG  1 
ATOM 2528 C CD1 . TYR A 1 553 ? 169.569 163.418 134.894 1.00 0.00  ? 553 TYR A CD1 1 
ATOM 2529 C CD2 . TYR A 1 553 ? 171.776 164.214 135.302 1.00 4.05  ? 553 TYR A CD2 1 
ATOM 2530 C CE1 . TYR A 1 553 ? 169.998 162.119 135.083 1.00 0.00  ? 553 TYR A CE1 1 
ATOM 2531 C CE2 . TYR A 1 553 ? 172.213 162.919 135.494 1.00 0.42  ? 553 TYR A CE2 1 
ATOM 2532 C CZ  . TYR A 1 553 ? 171.321 161.875 135.382 1.00 0.00  ? 553 TYR A CZ  1 
ATOM 2533 O OH  . TYR A 1 553 ? 171.755 160.585 135.572 1.00 0.00  ? 553 TYR A OH  1 
ATOM 2534 N N   . PRO A 1 554 ? 167.714 167.839 133.274 1.00 6.24  ? 554 PRO A N   1 
ATOM 2535 C CA  . PRO A 1 554 ? 167.185 169.115 132.766 1.00 4.35  ? 554 PRO A CA  1 
ATOM 2536 C C   . PRO A 1 554 ? 167.588 170.336 133.576 1.00 8.35  ? 554 PRO A C   1 
ATOM 2537 O O   . PRO A 1 554 ? 167.874 171.383 132.982 1.00 14.60 ? 554 PRO A O   1 
ATOM 2538 C CB  . PRO A 1 554 ? 165.668 168.888 132.803 1.00 3.90  ? 554 PRO A CB  1 
ATOM 2539 C CG  . PRO A 1 554 ? 165.487 167.941 133.944 1.00 4.37  ? 554 PRO A CG  1 
ATOM 2540 C CD  . PRO A 1 554 ? 166.641 166.981 133.807 1.00 5.90  ? 554 PRO A CD  1 
ATOM 2541 N N   . GLN A 1 555 ? 167.623 170.247 134.902 1.00 4.57  ? 555 GLN A N   1 
ATOM 2542 C CA  . GLN A 1 555 ? 167.864 171.403 135.756 1.00 3.05  ? 555 GLN A CA  1 
ATOM 2543 C C   . GLN A 1 555 ? 169.358 171.558 136.009 1.00 4.75  ? 555 GLN A C   1 
ATOM 2544 O O   . GLN A 1 555 ? 170.019 170.609 136.444 1.00 12.85 ? 555 GLN A O   1 
ATOM 2545 C CB  . GLN A 1 555 ? 167.110 171.269 137.079 1.00 7.37  ? 555 GLN A CB  1 
ATOM 2546 C CG  . GLN A 1 555 ? 165.693 171.830 137.059 1.00 6.99  ? 555 GLN A CG  1 
ATOM 2547 C CD  . GLN A 1 555 ? 165.621 173.254 136.533 1.00 7.02  ? 555 GLN A CD  1 
ATOM 2548 O OE1 . GLN A 1 555 ? 166.524 174.061 136.757 1.00 6.11  ? 555 GLN A OE1 1 
ATOM 2549 N NE2 . GLN A 1 555 ? 164.540 173.568 135.831 1.00 11.15 ? 555 GLN A NE2 1 
ATOM 2550 N N   . LYS A 1 556 ? 169.885 172.753 135.736 1.00 4.96  ? 556 LYS A N   1 
ATOM 2551 C CA  . LYS A 1 556 ? 171.273 173.058 136.062 1.00 2.86  ? 556 LYS A CA  1 
ATOM 2552 C C   . LYS A 1 556 ? 171.512 173.162 137.560 1.00 2.02  ? 556 LYS A C   1 
ATOM 2553 O O   . LYS A 1 556 ? 172.641 172.933 138.007 1.00 2.10  ? 556 LYS A O   1 
ATOM 2554 C CB  . LYS A 1 556 ? 171.702 174.363 135.389 1.00 1.29  ? 556 LYS A CB  1 
ATOM 2555 C CG  . LYS A 1 556 ? 172.563 174.174 134.157 1.00 3.47  ? 556 LYS A CG  1 
ATOM 2556 C CD  . LYS A 1 556 ? 173.484 175.362 133.948 1.00 4.30  ? 556 LYS A CD  1 
ATOM 2557 C CE  . LYS A 1 556 ? 172.815 176.446 133.122 1.00 4.95  ? 556 LYS A CE  1 
ATOM 2558 N NZ  . LYS A 1 556 ? 173.727 177.599 132.893 1.00 4.10  ? 556 LYS A NZ  1 
ATOM 2559 N N   . ALA A 1 557 ? 170.490 173.507 138.341 1.00 4.10  ? 557 ALA A N   1 
ATOM 2560 C CA  . ALA A 1 557 ? 170.614 173.600 139.788 1.00 3.19  ? 557 ALA A CA  1 
ATOM 2561 C C   . ALA A 1 557 ? 170.898 172.257 140.443 1.00 5.74  ? 557 ALA A C   1 
ATOM 2562 O O   . ALA A 1 557 ? 171.476 172.228 141.538 1.00 2.96  ? 557 ALA A O   1 
ATOM 2563 C CB  . ALA A 1 557 ? 169.341 174.204 140.390 1.00 2.82  ? 557 ALA A CB  1 
ATOM 2564 N N   . TYR A 1 558 ? 170.513 171.151 139.798 1.00 3.12  ? 558 TYR A N   1 
ATOM 2565 C CA  . TYR A 1 558 ? 170.819 169.832 140.340 1.00 4.32  ? 558 TYR A CA  1 
ATOM 2566 C C   . TYR A 1 558 ? 172.321 169.629 140.464 1.00 2.38  ? 558 TYR A C   1 
ATOM 2567 O O   . TYR A 1 558 ? 172.799 169.099 141.470 1.00 0.00  ? 558 TYR A O   1 
ATOM 2568 C CB  . TYR A 1 558 ? 170.217 168.738 139.458 1.00 3.97  ? 558 TYR A CB  1 
ATOM 2569 C CG  . TYR A 1 558 ? 168.708 168.670 139.464 1.00 4.94  ? 558 TYR A CG  1 
ATOM 2570 C CD1 . TYR A 1 558 ? 167.970 169.185 140.522 1.00 5.18  ? 558 TYR A CD1 1 
ATOM 2571 C CD2 . TYR A 1 558 ? 168.023 168.064 138.422 1.00 4.91  ? 558 TYR A CD2 1 
ATOM 2572 C CE1 . TYR A 1 558 ? 166.590 169.116 140.529 1.00 3.56  ? 558 TYR A CE1 1 
ATOM 2573 C CE2 . TYR A 1 558 ? 166.646 167.989 138.421 1.00 5.43  ? 558 TYR A CE2 1 
ATOM 2574 C CZ  . TYR A 1 558 ? 165.935 168.516 139.477 1.00 4.14  ? 558 TYR A CZ  1 
ATOM 2575 O OH  . TYR A 1 558 ? 164.562 168.440 139.476 1.00 9.99  ? 558 TYR A OH  1 
ATOM 2576 N N   . TYR A 1 559 ? 173.080 170.050 139.451 1.00 2.95  ? 559 TYR A N   1 
ATOM 2577 C CA  . TYR A 1 559 ? 174.524 169.848 139.466 1.00 0.67  ? 559 TYR A CA  1 
ATOM 2578 C C   . TYR A 1 559 ? 175.196 170.678 140.556 1.00 2.03  ? 559 TYR A C   1 
ATOM 2579 O O   . TYR A 1 559 ? 176.085 170.182 141.255 1.00 4.00  ? 559 TYR A O   1 
ATOM 2580 C CB  . TYR A 1 559 ? 175.108 170.172 138.091 1.00 3.40  ? 559 TYR A CB  1 
ATOM 2581 C CG  . TYR A 1 559 ? 174.631 169.253 136.984 1.00 0.53  ? 559 TYR A CG  1 
ATOM 2582 C CD1 . TYR A 1 559 ? 173.341 169.355 136.474 1.00 3.61  ? 559 TYR A CD1 1 
ATOM 2583 C CD2 . TYR A 1 559 ? 175.470 168.284 136.448 1.00 0.00  ? 559 TYR A CD2 1 
ATOM 2584 C CE1 . TYR A 1 559 ? 172.902 168.520 135.468 1.00 5.65  ? 559 TYR A CE1 1 
ATOM 2585 C CE2 . TYR A 1 559 ? 175.038 167.444 135.440 1.00 0.35  ? 559 TYR A CE2 1 
ATOM 2586 C CZ  . TYR A 1 559 ? 173.754 167.566 134.954 1.00 3.08  ? 559 TYR A CZ  1 
ATOM 2587 O OH  . TYR A 1 559 ? 173.314 166.734 133.952 1.00 5.07  ? 559 TYR A OH  1 
ATOM 2588 N N   . TYR A 1 560 ? 174.786 171.939 140.721 1.00 0.14  ? 560 TYR A N   1 
ATOM 2589 C CA  . TYR A 1 560 ? 175.362 172.771 141.777 1.00 3.41  ? 560 TYR A CA  1 
ATOM 2590 C C   . TYR A 1 560 ? 175.012 172.234 143.161 1.00 0.00  ? 560 TYR A C   1 
ATOM 2591 O O   . TYR A 1 560 ? 175.874 172.174 144.052 1.00 2.93  ? 560 TYR A O   1 
ATOM 2592 C CB  . TYR A 1 560 ? 174.885 174.216 141.630 1.00 2.09  ? 560 TYR A CB  1 
ATOM 2593 C CG  . TYR A 1 560 ? 175.280 174.868 140.327 1.00 1.54  ? 560 TYR A CG  1 
ATOM 2594 C CD1 . TYR A 1 560 ? 176.590 174.818 139.873 1.00 3.50  ? 560 TYR A CD1 1 
ATOM 2595 C CD2 . TYR A 1 560 ? 174.344 175.539 139.553 1.00 1.96  ? 560 TYR A CD2 1 
ATOM 2596 C CE1 . TYR A 1 560 ? 176.956 175.414 138.685 1.00 2.12  ? 560 TYR A CE1 1 
ATOM 2597 C CE2 . TYR A 1 560 ? 174.701 176.137 138.361 1.00 4.00  ? 560 TYR A CE2 1 
ATOM 2598 C CZ  . TYR A 1 560 ? 176.008 176.071 137.932 1.00 3.80  ? 560 TYR A CZ  1 
ATOM 2599 O OH  . TYR A 1 560 ? 176.370 176.665 136.746 1.00 5.64  ? 560 TYR A OH  1 
ATOM 2600 N N   . CYS A 1 561 ? 173.751 171.840 143.358 1.00 0.00  ? 561 CYS A N   1 
ATOM 2601 C CA  . CYS A 1 561 ? 173.351 171.253 144.631 1.00 2.02  ? 561 CYS A CA  1 
ATOM 2602 C C   . CYS A 1 561 ? 174.127 169.972 144.910 1.00 2.10  ? 561 CYS A C   1 
ATOM 2603 O O   . CYS A 1 561 ? 174.534 169.719 146.050 1.00 4.21  ? 561 CYS A O   1 
ATOM 2604 C CB  . CYS A 1 561 ? 171.846 170.983 144.632 1.00 4.33  ? 561 CYS A CB  1 
ATOM 2605 S SG  . CYS A 1 561 ? 170.816 172.454 144.838 1.00 15.29 ? 561 CYS A SG  1 
ATOM 2606 N N   . ALA A 1 562 ? 174.346 169.154 143.875 1.00 1.28  ? 562 ALA A N   1 
ATOM 2607 C CA  . ALA A 1 562 ? 175.118 167.928 144.029 1.00 2.76  ? 562 ALA A CA  1 
ATOM 2608 C C   . ALA A 1 562 ? 176.565 168.226 144.392 1.00 0.74  ? 562 ALA A C   1 
ATOM 2609 O O   . ALA A 1 562 ? 177.156 167.531 145.223 1.00 3.52  ? 562 ALA A O   1 
ATOM 2610 C CB  . ALA A 1 562 ? 175.045 167.100 142.749 1.00 0.00  ? 562 ALA A CB  1 
ATOM 2611 N N   . ILE A 1 563 ? 177.154 169.252 143.775 1.00 0.49  ? 563 ILE A N   1 
ATOM 2612 C CA  . ILE A 1 563 ? 178.523 169.636 144.115 1.00 0.86  ? 563 ILE A CA  1 
ATOM 2613 C C   . ILE A 1 563 ? 178.612 170.010 145.589 1.00 0.48  ? 563 ILE A C   1 
ATOM 2614 O O   . ILE A 1 563 ? 179.505 169.551 146.313 1.00 6.23  ? 563 ILE A O   1 
ATOM 2615 C CB  . ILE A 1 563 ? 179.000 170.787 143.211 1.00 1.42  ? 563 ILE A CB  1 
ATOM 2616 C CG1 . ILE A 1 563 ? 179.227 170.294 141.783 1.00 2.63  ? 563 ILE A CG1 1 
ATOM 2617 C CG2 . ILE A 1 563 ? 180.273 171.414 143.763 1.00 3.94  ? 563 ILE A CG2 1 
ATOM 2618 C CD1 . ILE A 1 563 ? 179.477 171.407 140.792 1.00 1.66  ? 563 ILE A CD1 1 
ATOM 2619 N N   . ILE A 1 564 ? 177.669 170.830 146.059 1.00 2.86  ? 564 ILE A N   1 
ATOM 2620 C CA  . ILE A 1 564 ? 177.696 171.271 147.454 1.00 4.42  ? 564 ILE A CA  1 
ATOM 2621 C C   . ILE A 1 564 ? 177.524 170.081 148.397 1.00 2.38  ? 564 ILE A C   1 
ATOM 2622 O O   . ILE A 1 564 ? 178.282 169.911 149.368 1.00 3.80  ? 564 ILE A O   1 
ATOM 2623 C CB  . ILE A 1 564 ? 176.621 172.345 147.697 1.00 3.86  ? 564 ILE A CB  1 
ATOM 2624 C CG1 . ILE A 1 564 ? 176.843 173.545 146.775 1.00 3.48  ? 564 ILE A CG1 1 
ATOM 2625 C CG2 . ILE A 1 564 ? 176.624 172.787 149.153 1.00 3.82  ? 564 ILE A CG2 1 
ATOM 2626 C CD1 . ILE A 1 564 ? 178.188 174.208 146.947 1.00 6.17  ? 564 ILE A CD1 1 
ATOM 2627 N N   . GLU A 1 565 ? 176.523 169.238 148.122 1.00 0.27  ? 565 GLU A N   1 
ATOM 2628 C CA  . GLU A 1 565 ? 176.259 168.108 149.005 1.00 2.87  ? 565 GLU A CA  1 
ATOM 2629 C C   . GLU A 1 565 ? 177.434 167.140 149.023 1.00 5.04  ? 565 GLU A C   1 
ATOM 2630 O O   . GLU A 1 565 ? 177.779 166.604 150.078 1.00 7.56  ? 565 GLU A O   1 
ATOM 2631 C CB  . GLU A 1 565 ? 174.956 167.399 148.612 1.00 2.83  ? 565 GLU A CB  1 
ATOM 2632 C CG  . GLU A 1 565 ? 174.970 166.629 147.296 1.00 2.34  ? 565 GLU A CG  1 
ATOM 2633 C CD  . GLU A 1 565 ? 175.501 165.211 147.433 1.00 3.84  ? 565 GLU A CD  1 
ATOM 2634 O OE1 . GLU A 1 565 ? 175.265 164.579 148.482 1.00 0.00  ? 565 GLU A OE1 1 
ATOM 2635 O OE2 . GLU A 1 565 ? 176.169 164.736 146.491 1.00 7.47  ? 565 GLU A OE2 1 
ATOM 2636 N N   . ASP A 1 566 ? 178.070 166.911 147.871 1.00 0.00  ? 566 ASP A N   1 
ATOM 2637 C CA  . ASP A 1 566 ? 179.217 166.012 147.830 1.00 2.16  ? 566 ASP A CA  1 
ATOM 2638 C C   . ASP A 1 566 ? 180.398 166.589 148.596 1.00 0.01  ? 566 ASP A C   1 
ATOM 2639 O O   . ASP A 1 566 ? 181.102 165.855 149.300 1.00 2.59  ? 566 ASP A O   1 
ATOM 2640 C CB  . ASP A 1 566 ? 179.607 165.718 146.383 1.00 0.13  ? 566 ASP A CB  1 
ATOM 2641 C CG  . ASP A 1 566 ? 180.358 164.411 146.239 1.00 0.00  ? 566 ASP A CG  1 
ATOM 2642 O OD1 . ASP A 1 566 ? 179.708 163.348 146.263 1.00 4.06  ? 566 ASP A OD1 1 
ATOM 2643 O OD2 . ASP A 1 566 ? 181.597 164.446 146.104 1.00 0.00  ? 566 ASP A OD2 1 
ATOM 2644 N N   . VAL A 1 567 ? 180.619 167.902 148.486 1.00 3.11  ? 567 VAL A N   1 
ATOM 2645 C CA  . VAL A 1 567 ? 181.706 168.536 149.228 1.00 2.15  ? 567 VAL A CA  1 
ATOM 2646 C C   . VAL A 1 567 ? 181.514 168.329 150.726 1.00 2.22  ? 567 VAL A C   1 
ATOM 2647 O O   . VAL A 1 567 ? 182.455 167.977 151.447 1.00 3.99  ? 567 VAL A O   1 
ATOM 2648 C CB  . VAL A 1 567 ? 181.804 170.031 148.872 1.00 3.29  ? 567 VAL A CB  1 
ATOM 2649 C CG1 . VAL A 1 567 ? 182.650 170.768 149.896 1.00 1.55  ? 567 VAL A CG1 1 
ATOM 2650 C CG2 . VAL A 1 567 ? 182.387 170.212 147.479 1.00 1.57  ? 567 VAL A CG2 1 
ATOM 2651 N N   . ILE A 1 568 ? 180.290 168.533 151.216 1.00 2.54  ? 568 ILE A N   1 
ATOM 2652 C CA  . ILE A 1 568 ? 180.037 168.357 152.649 1.00 1.64  ? 568 ILE A CA  1 
ATOM 2653 C C   . ILE A 1 568 ? 180.134 166.880 153.044 1.00 1.69  ? 568 ILE A C   1 
ATOM 2654 O O   . ILE A 1 568 ? 180.777 166.513 154.044 1.00 2.60  ? 568 ILE A O   1 
ATOM 2655 C CB  . ILE A 1 568 ? 178.671 168.961 153.023 1.00 1.48  ? 568 ILE A CB  1 
ATOM 2656 C CG1 . ILE A 1 568 ? 178.721 170.488 152.916 1.00 4.31  ? 568 ILE A CG1 1 
ATOM 2657 C CG2 . ILE A 1 568 ? 178.251 168.530 154.416 1.00 3.24  ? 568 ILE A CG2 1 
ATOM 2658 C CD1 . ILE A 1 568 ? 177.369 171.146 152.751 1.00 2.82  ? 568 ILE A CD1 1 
ATOM 2659 N N   . LEU A 1 569 ? 179.513 166.006 152.256 1.00 0.00  ? 569 LEU A N   1 
ATOM 2660 C CA  . LEU A 1 569 ? 179.359 164.620 152.661 1.00 0.00  ? 569 LEU A CA  1 
ATOM 2661 C C   . LEU A 1 569 ? 180.635 163.803 152.511 1.00 0.49  ? 569 LEU A C   1 
ATOM 2662 O O   . LEU A 1 569 ? 180.766 162.785 153.189 1.00 1.37  ? 569 LEU A O   1 
ATOM 2663 C CB  . LEU A 1 569 ? 178.211 163.975 151.879 1.00 0.44  ? 569 LEU A CB  1 
ATOM 2664 C CG  . LEU A 1 569 ? 176.822 164.505 152.256 1.00 0.00  ? 569 LEU A CG  1 
ATOM 2665 C CD1 . LEU A 1 569 ? 175.711 163.624 151.702 1.00 0.19  ? 569 LEU A CD1 1 
ATOM 2666 C CD2 . LEU A 1 569 ? 176.687 164.660 153.768 1.00 0.00  ? 569 LEU A CD2 1 
ATOM 2667 N N   . ARG A 1 570 ? 181.593 164.225 151.680 1.00 0.00  ? 570 ARG A N   1 
ATOM 2668 C CA  . ARG A 1 570 ? 182.870 163.514 151.651 1.00 0.94  ? 570 ARG A CA  1 
ATOM 2669 C C   . ARG A 1 570 ? 183.625 163.681 152.967 1.00 0.79  ? 570 ARG A C   1 
ATOM 2670 O O   . ARG A 1 570 ? 184.178 162.710 153.504 1.00 2.51  ? 570 ARG A O   1 
ATOM 2671 C CB  . ARG A 1 570 ? 183.719 163.993 150.473 1.00 0.00  ? 570 ARG A CB  1 
ATOM 2672 C CG  . ARG A 1 570 ? 183.491 163.211 149.184 1.00 0.54  ? 570 ARG A CG  1 
ATOM 2673 C CD  . ARG A 1 570 ? 183.752 161.724 149.377 1.00 0.00  ? 570 ARG A CD  1 
ATOM 2674 N NE  . ARG A 1 570 ? 183.793 161.000 148.113 1.00 1.31  ? 570 ARG A NE  1 
ATOM 2675 C CZ  . ARG A 1 570 ? 184.033 159.700 148.002 1.00 0.91  ? 570 ARG A CZ  1 
ATOM 2676 N NH1 . ARG A 1 570 ? 184.265 158.946 149.063 1.00 1.38  ? 570 ARG A NH1 1 
ATOM 2677 N NH2 . ARG A 1 570 ? 184.041 159.143 146.795 1.00 0.00  ? 570 ARG A NH2 1 
ATOM 2678 N N   . PHE A 1 571 ? 183.652 164.905 153.502 1.00 1.50  ? 571 PHE A N   1 
ATOM 2679 C CA  . PHE A 1 571 ? 184.241 165.127 154.819 1.00 2.73  ? 571 PHE A CA  1 
ATOM 2680 C C   . PHE A 1 571 ? 183.473 164.370 155.893 1.00 2.79  ? 571 PHE A C   1 
ATOM 2681 O O   . PHE A 1 571 ? 184.077 163.756 156.788 1.00 0.00  ? 571 PHE A O   1 
ATOM 2682 C CB  . PHE A 1 571 ? 184.277 166.622 155.135 1.00 2.75  ? 571 PHE A CB  1 
ATOM 2683 C CG  . PHE A 1 571 ? 185.354 167.370 154.407 1.00 0.86  ? 571 PHE A CG  1 
ATOM 2684 C CD1 . PHE A 1 571 ? 186.648 167.394 154.896 1.00 0.57  ? 571 PHE A CD1 1 
ATOM 2685 C CD2 . PHE A 1 571 ? 185.074 168.048 153.235 1.00 3.95  ? 571 PHE A CD2 1 
ATOM 2686 C CE1 . PHE A 1 571 ? 187.641 168.081 154.229 1.00 0.77  ? 571 PHE A CE1 1 
ATOM 2687 C CE2 . PHE A 1 571 ? 186.064 168.735 152.564 1.00 2.50  ? 571 PHE A CE2 1 
ATOM 2688 C CZ  . PHE A 1 571 ? 187.349 168.752 153.062 1.00 2.91  ? 571 PHE A CZ  1 
ATOM 2689 N N   . ALA A 1 572 ? 182.137 164.390 155.814 1.00 5.20  ? 572 ALA A N   1 
ATOM 2690 C CA  . ALA A 1 572 ? 181.346 163.611 156.765 1.00 2.18  ? 572 ALA A CA  1 
ATOM 2691 C C   . ALA A 1 572 ? 181.705 162.126 156.707 1.00 2.43  ? 572 ALA A C   1 
ATOM 2692 O O   . ALA A 1 572 ? 181.830 161.466 157.746 1.00 5.73  ? 572 ALA A O   1 
ATOM 2693 C CB  . ALA A 1 572 ? 179.855 163.816 156.501 1.00 0.51  ? 572 ALA A CB  1 
ATOM 2694 N N   . TRP A 1 573 ? 181.895 161.590 155.499 1.00 0.00  ? 573 TRP A N   1 
ATOM 2695 C CA  . TRP A 1 573 ? 182.203 160.172 155.337 1.00 0.00  ? 573 TRP A CA  1 
ATOM 2696 C C   . TRP A 1 573 ? 183.583 159.827 155.882 1.00 0.00  ? 573 TRP A C   1 
ATOM 2697 O O   . TRP A 1 573 ? 183.758 158.782 156.519 1.00 0.00  ? 573 TRP A O   1 
ATOM 2698 C CB  . TRP A 1 573 ? 182.100 159.788 153.863 1.00 1.48  ? 573 TRP A CB  1 
ATOM 2699 C CG  . TRP A 1 573 ? 182.777 158.502 153.520 1.00 1.34  ? 573 TRP A CG  1 
ATOM 2700 C CD1 . TRP A 1 573 ? 182.322 157.245 153.777 1.00 0.00  ? 573 TRP A CD1 1 
ATOM 2701 C CD2 . TRP A 1 573 ? 184.034 158.346 152.852 1.00 2.01  ? 573 TRP A CD2 1 
ATOM 2702 N NE1 . TRP A 1 573 ? 183.212 156.314 153.307 1.00 0.03  ? 573 TRP A NE1 1 
ATOM 2703 C CE2 . TRP A 1 573 ? 184.274 156.963 152.736 1.00 1.57  ? 573 TRP A CE2 1 
ATOM 2704 C CE3 . TRP A 1 573 ? 184.978 159.240 152.339 1.00 3.56  ? 573 TRP A CE3 1 
ATOM 2705 C CZ2 . TRP A 1 573 ? 185.420 156.452 152.128 1.00 0.76  ? 573 TRP A CZ2 1 
ATOM 2706 C CZ3 . TRP A 1 573 ? 186.117 158.731 151.737 1.00 2.57  ? 573 TRP A CZ3 1 
ATOM 2707 C CH2 . TRP A 1 573 ? 186.327 157.350 151.636 1.00 1.18  ? 573 TRP A CH2 1 
ATOM 2708 N N   . THR A 1 574 ? 184.581 160.673 155.616 1.00 0.95  ? 574 THR A N   1 
ATOM 2709 C CA  . THR A 1 574 ? 185.910 160.413 156.162 1.00 2.05  ? 574 THR A CA  1 
ATOM 2710 C C   . THR A 1 574 ? 185.883 160.426 157.686 1.00 6.98  ? 574 THR A C   1 
ATOM 2711 O O   . THR A 1 574 ? 186.467 159.546 158.336 1.00 4.07  ? 574 THR A O   1 
ATOM 2712 C CB  . THR A 1 574 ? 186.921 161.431 155.634 1.00 2.22  ? 574 THR A CB  1 
ATOM 2713 O OG1 . THR A 1 574 ? 186.317 162.727 155.574 1.00 6.30  ? 574 THR A OG1 1 
ATOM 2714 C CG2 . THR A 1 574 ? 187.408 161.034 154.248 1.00 4.62  ? 574 THR A CG2 1 
ATOM 2715 N N   . ILE A 1 575 ? 185.176 161.395 158.277 1.00 3.09  ? 575 ILE A N   1 
ATOM 2716 C CA  . ILE A 1 575 ? 185.107 161.428 159.734 1.00 1.69  ? 575 ILE A CA  1 
ATOM 2717 C C   . ILE A 1 575 ? 184.352 160.214 160.275 1.00 3.00  ? 575 ILE A C   1 
ATOM 2718 O O   . ILE A 1 575 ? 184.696 159.693 161.342 1.00 6.31  ? 575 ILE A O   1 
ATOM 2719 C CB  . ILE A 1 575 ? 184.508 162.762 160.227 1.00 3.48  ? 575 ILE A CB  1 
ATOM 2720 C CG1 . ILE A 1 575 ? 185.185 163.196 161.528 1.00 7.02  ? 575 ILE A CG1 1 
ATOM 2721 C CG2 . ILE A 1 575 ? 183.015 162.659 160.465 1.00 0.32  ? 575 ILE A CG2 1 
ATOM 2722 C CD1 . ILE A 1 575 ? 186.692 163.139 161.489 1.00 5.47  ? 575 ILE A CD1 1 
ATOM 2723 N N   . GLN A 1 576 ? 183.334 159.725 159.557 1.00 2.63  ? 576 GLN A N   1 
ATOM 2724 C CA  . GLN A 1 576 ? 182.568 158.595 160.077 1.00 2.97  ? 576 GLN A CA  1 
ATOM 2725 C C   . GLN A 1 576 ? 183.365 157.297 159.971 1.00 1.34  ? 576 GLN A C   1 
ATOM 2726 O O   . GLN A 1 576 ? 183.290 156.443 160.863 1.00 3.79  ? 576 GLN A O   1 
ATOM 2727 C CB  . GLN A 1 576 ? 181.209 158.510 159.364 1.00 0.32  ? 576 GLN A CB  1 
ATOM 2728 C CG  . GLN A 1 576 ? 180.310 157.299 159.689 1.00 2.24  ? 576 GLN A CG  1 
ATOM 2729 C CD  . GLN A 1 576 ? 180.773 155.986 159.098 1.00 5.63  ? 576 GLN A CD  1 
ATOM 2730 O OE1 . GLN A 1 576 ? 180.796 154.956 159.771 1.00 5.71  ? 576 GLN A OE1 1 
ATOM 2731 N NE2 . GLN A 1 576 ? 181.083 156.005 157.815 1.00 8.30  ? 576 GLN A NE2 1 
ATOM 2732 N N   . ILE A 1 577 ? 184.144 157.136 158.895 1.00 2.22  ? 577 ILE A N   1 
ATOM 2733 C CA  . ILE A 1 577 ? 185.070 156.007 158.814 1.00 3.47  ? 577 ILE A CA  1 
ATOM 2734 C C   . ILE A 1 577 ? 186.077 156.070 159.954 1.00 5.47  ? 577 ILE A C   1 
ATOM 2735 O O   . ILE A 1 577 ? 186.398 155.049 160.575 1.00 7.52  ? 577 ILE A O   1 
ATOM 2736 C CB  . ILE A 1 577 ? 185.772 155.960 157.440 1.00 4.18  ? 577 ILE A CB  1 
ATOM 2737 C CG1 . ILE A 1 577 ? 185.088 154.977 156.485 1.00 4.28  ? 577 ILE A CG1 1 
ATOM 2738 C CG2 . ILE A 1 577 ? 187.224 155.536 157.582 1.00 0.70  ? 577 ILE A CG2 1 
ATOM 2739 C CD1 . ILE A 1 577 ? 183.622 155.142 156.332 1.00 1.17  ? 577 ILE A CD1 1 
ATOM 2740 N N   . SER A 1 578 ? 186.587 157.268 160.256 1.00 3.16  ? 578 SER A N   1 
ATOM 2741 C CA  . SER A 1 578 ? 187.529 157.394 161.364 1.00 3.72  ? 578 SER A CA  1 
ATOM 2742 C C   . SER A 1 578 ? 186.880 157.015 162.692 1.00 6.00  ? 578 SER A C   1 
ATOM 2743 O O   . SER A 1 578 ? 187.501 156.344 163.524 1.00 4.60  ? 578 SER A O   1 
ATOM 2744 C CB  . SER A 1 578 ? 188.082 158.817 161.429 1.00 5.16  ? 578 SER A CB  1 
ATOM 2745 O OG  . SER A 1 578 ? 188.934 159.086 160.332 1.00 6.19  ? 578 SER A OG  1 
ATOM 2746 N N   . ILE A 1 579 ? 185.635 157.439 162.910 1.00 4.90  ? 579 ILE A N   1 
ATOM 2747 C CA  . ILE A 1 579 ? 184.978 157.197 164.191 1.00 3.34  ? 579 ILE A CA  1 
ATOM 2748 C C   . ILE A 1 579 ? 184.626 155.722 164.370 1.00 2.54  ? 579 ILE A C   1 
ATOM 2749 O O   . ILE A 1 579 ? 184.837 155.154 165.446 1.00 6.62  ? 579 ILE A O   1 
ATOM 2750 C CB  . ILE A 1 579 ? 183.738 158.101 164.327 1.00 3.05  ? 579 ILE A CB  1 
ATOM 2751 C CG1 . ILE A 1 579 ? 184.139 159.468 164.883 1.00 2.30  ? 579 ILE A CG1 1 
ATOM 2752 C CG2 . ILE A 1 579 ? 182.690 157.454 165.222 1.00 2.06  ? 579 ILE A CG2 1 
ATOM 2753 C CD1 . ILE A 1 579 ? 183.126 160.556 164.617 1.00 3.00  ? 579 ILE A CD1 1 
ATOM 2754 N N   . THR A 1 580 ? 184.077 155.078 163.339 1.00 0.92  ? 580 THR A N   1 
ATOM 2755 C CA  . THR A 1 580 ? 183.576 153.715 163.500 1.00 0.69  ? 580 THR A CA  1 
ATOM 2756 C C   . THR A 1 580 ? 184.672 152.701 163.814 1.00 7.22  ? 580 THR A C   1 
ATOM 2757 O O   . THR A 1 580 ? 184.469 151.837 164.674 1.00 10.13 ? 580 THR A O   1 
ATOM 2758 C CB  . THR A 1 580 ? 182.814 153.283 162.244 1.00 4.53  ? 580 THR A CB  1 
ATOM 2759 O OG1 . THR A 1 580 ? 181.626 154.074 162.112 1.00 6.15  ? 580 THR A OG1 1 
ATOM 2760 C CG2 . THR A 1 580 ? 182.424 151.812 162.322 1.00 3.44  ? 580 THR A CG2 1 
ATOM 2761 N N   . SER A 1 581 ? 185.827 152.792 163.157 1.00 9.97  ? 581 SER A N   1 
ATOM 2762 C CA  . SER A 1 581 ? 186.891 151.810 163.307 1.00 6.23  ? 581 SER A CA  1 
ATOM 2763 C C   . SER A 1 581 ? 187.849 152.145 164.446 1.00 9.29  ? 581 SER A C   1 
ATOM 2764 O O   . SER A 1 581 ? 188.817 151.411 164.668 1.00 9.47  ? 581 SER A O   1 
ATOM 2765 C CB  . SER A 1 581 ? 187.666 151.678 161.995 1.00 5.93  ? 581 SER A CB  1 
ATOM 2766 O OG  . SER A 1 581 ? 188.342 150.436 161.923 1.00 6.78  ? 581 SER A OG  1 
ATOM 2767 N N   . THR A 1 582 ? 187.592 153.226 165.181 1.00 5.52  ? 582 THR A N   1 
ATOM 2768 C CA  . THR A 1 582 ? 188.586 153.764 166.099 1.00 5.77  ? 582 THR A CA  1 
ATOM 2769 C C   . THR A 1 582 ? 187.919 154.460 167.283 1.00 12.47 ? 582 THR A C   1 
ATOM 2770 O O   . THR A 1 582 ? 186.905 155.144 167.119 1.00 17.37 ? 582 THR A O   1 
ATOM 2771 C CB  . THR A 1 582 ? 189.517 154.711 165.331 1.00 6.53  ? 582 THR A CB  1 
ATOM 2772 O OG1 . THR A 1 582 ? 190.467 153.944 164.581 1.00 11.90 ? 582 THR A OG1 1 
ATOM 2773 C CG2 . THR A 1 582 ? 190.252 155.653 166.250 1.00 9.27  ? 582 THR A CG2 1 
ATOM 2774 N N   . THR A 1 583 ? 188.489 154.304 168.479 1.00 8.73  ? 583 THR A N   1 
ATOM 2775 C CA  . THR A 1 583 ? 187.876 154.776 169.718 1.00 7.38  ? 583 THR A CA  1 
ATOM 2776 C C   . THR A 1 583 ? 187.982 156.301 169.810 1.00 9.78  ? 583 THR A C   1 
ATOM 2777 O O   . THR A 1 583 ? 187.673 156.899 170.846 1.00 16.17 ? 583 THR A O   1 
ATOM 2778 C CB  . THR A 1 583 ? 188.542 154.071 170.913 1.00 5.83  ? 583 THR A CB  1 
ATOM 2779 O OG1 . THR A 1 583 ? 188.453 152.654 170.726 1.00 10.14 ? 583 THR A OG1 1 
ATOM 2780 C CG2 . THR A 1 583 ? 187.832 154.384 172.226 1.00 5.34  ? 583 THR A CG2 1 
ATOM 2781 N N   . LEU A 1 584 ? 188.398 156.936 168.711 1.00 4.50  ? 584 LEU A N   1 
ATOM 2782 C CA  . LEU A 1 584 ? 188.612 158.378 168.609 1.00 7.87  ? 584 LEU A CA  1 
ATOM 2783 C C   . LEU A 1 584 ? 187.576 159.212 169.356 1.00 8.24  ? 584 LEU A C   1 
ATOM 2784 O O   . LEU A 1 584 ? 187.936 160.131 170.099 1.00 13.90 ? 584 LEU A O   1 
ATOM 2785 C CB  . LEU A 1 584 ? 188.627 158.792 167.136 1.00 7.94  ? 584 LEU A CB  1 
ATOM 2786 C CG  . LEU A 1 584 ? 189.762 158.254 166.264 1.00 7.00  ? 584 LEU A CG  1 
ATOM 2787 C CD1 . LEU A 1 584 ? 189.543 158.639 164.811 1.00 10.12 ? 584 LEU A CD1 1 
ATOM 2788 C CD2 . LEU A 1 584 ? 191.102 158.774 166.762 1.00 7.23  ? 584 LEU A CD2 1 
ATOM 2789 N N   . LEU A 1 585 ? 186.292 158.904 169.176 1.00 8.46  ? 585 LEU A N   1 
ATOM 2790 C CA  . LEU A 1 585 ? 185.229 159.662 169.822 1.00 6.22  ? 585 LEU A CA  1 
ATOM 2791 C C   . LEU A 1 585 ? 184.354 158.721 170.632 1.00 8.31  ? 585 LEU A C   1 
ATOM 2792 O O   . LEU A 1 585 ? 183.301 158.291 170.136 1.00 9.06  ? 585 LEU A O   1 
ATOM 2793 C CB  . LEU A 1 585 ? 184.393 160.399 168.783 1.00 5.39  ? 585 LEU A CB  1 
ATOM 2794 C CG  . LEU A 1 585 ? 183.814 161.755 169.185 1.00 9.48  ? 585 LEU A CG  1 
ATOM 2795 C CD1 . LEU A 1 585 ? 184.905 162.662 169.723 1.00 8.20  ? 585 LEU A CD1 1 
ATOM 2796 C CD2 . LEU A 1 585 ? 183.117 162.402 167.999 1.00 7.47  ? 585 LEU A CD2 1 
ATOM 2797 N N   . PRO A 1 586 ? 184.728 158.385 171.866 1.00 5.37  ? 586 PRO A N   1 
ATOM 2798 C CA  . PRO A 1 586 ? 184.008 157.350 172.629 1.00 7.51  ? 586 PRO A CA  1 
ATOM 2799 C C   . PRO A 1 586 ? 182.657 157.761 173.201 1.00 10.52 ? 586 PRO A C   1 
ATOM 2800 O O   . PRO A 1 586 ? 181.953 156.889 173.723 1.00 10.80 ? 586 PRO A O   1 
ATOM 2801 C CB  . PRO A 1 586 ? 184.995 157.059 173.766 1.00 10.46 ? 586 PRO A CB  1 
ATOM 2802 C CG  . PRO A 1 586 ? 185.649 158.374 174.000 1.00 9.95  ? 586 PRO A CG  1 
ATOM 2803 C CD  . PRO A 1 586 ? 185.877 158.918 172.618 1.00 7.66  ? 586 PRO A CD  1 
ATOM 2804 N N   . HIS A 1 587 ? 182.272 159.035 173.122 1.00 10.53 ? 587 HIS A N   1 
ATOM 2805 C CA  . HIS A 1 587 ? 181.010 159.487 173.698 1.00 5.84  ? 587 HIS A CA  1 
ATOM 2806 C C   . HIS A 1 587 ? 179.983 159.825 172.627 1.00 10.84 ? 587 HIS A C   1 
ATOM 2807 O O   . HIS A 1 587 ? 178.879 159.270 172.649 1.00 13.27 ? 587 HIS A O   1 
ATOM 2808 C CB  . HIS A 1 587 ? 181.242 160.691 174.623 1.00 8.03  ? 587 HIS A CB  1 
ATOM 2809 C CG  . HIS A 1 587 ? 182.181 161.717 174.068 1.00 10.23 ? 587 HIS A CG  1 
ATOM 2810 N ND1 . HIS A 1 587 ? 183.528 161.483 173.894 1.00 8.49  ? 587 HIS A ND1 1 
ATOM 2811 C CD2 . HIS A 1 587 ? 181.964 162.987 173.652 1.00 9.84  ? 587 HIS A CD2 1 
ATOM 2812 C CE1 . HIS A 1 587 ? 184.100 162.563 173.393 1.00 9.84  ? 587 HIS A CE1 1 
ATOM 2813 N NE2 . HIS A 1 587 ? 183.172 163.490 173.236 1.00 9.65  ? 587 HIS A NE2 1 
ATOM 2814 N N   . SER A 1 588 ? 180.347 160.690 171.676 1.00 9.95  ? 588 SER A N   1 
ATOM 2815 C CA  . SER A 1 588 ? 179.374 161.134 170.642 1.00 3.67  ? 588 SER A CA  1 
ATOM 2816 C C   . SER A 1 588 ? 179.465 160.249 169.391 1.00 6.31  ? 588 SER A C   1 
ATOM 2817 O O   . SER A 1 588 ? 178.419 160.047 168.738 1.00 8.87  ? 588 SER A O   1 
ATOM 2818 C CB  . SER A 1 588 ? 179.579 162.586 170.291 1.00 7.45  ? 588 SER A CB  1 
ATOM 2819 O OG  . SER A 1 588 ? 180.853 162.793 169.696 1.00 9.18  ? 588 SER A OG  1 
ATOM 2820 N N   . GLY A 1 589 ? 180.659 159.739 169.075 1.00 11.40 ? 589 GLY A N   1 
ATOM 2821 C CA  . GLY A 1 589 ? 180.851 158.930 167.853 1.00 7.66  ? 589 GLY A CA  1 
ATOM 2822 C C   . GLY A 1 589 ? 179.666 158.032 167.549 1.00 7.30  ? 589 GLY A C   1 
ATOM 2823 O O   . GLY A 1 589 ? 179.187 158.070 166.398 1.00 10.87 ? 589 GLY A O   1 
ATOM 2824 N N   . ASP A 1 590 ? 179.216 157.238 168.526 1.00 6.82  ? 590 ASP A N   1 
ATOM 2825 C CA  . ASP A 1 590 ? 178.096 156.279 168.311 1.00 8.05  ? 590 ASP A CA  1 
ATOM 2826 C C   . ASP A 1 590 ? 176.987 156.925 167.474 1.00 3.20  ? 590 ASP A C   1 
ATOM 2827 O O   . ASP A 1 590 ? 176.718 156.428 166.358 1.00 5.01  ? 590 ASP A O   1 
ATOM 2828 C CB  . ASP A 1 590 ? 177.543 155.775 169.635 1.00 6.53  ? 590 ASP A CB  1 
ATOM 2829 C CG  . ASP A 1 590 ? 176.456 154.716 169.531 1.00 6.08  ? 590 ASP A CG  1 
ATOM 2830 O OD1 . ASP A 1 590 ? 176.120 154.333 168.391 1.00 13.84 ? 590 ASP A OD1 1 
ATOM 2831 O OD2 . ASP A 1 590 ? 175.952 154.284 170.589 1.00 9.11  ? 590 ASP A OD2 1 
ATOM 2832 N N   . ILE A 1 591 ? 176.355 157.976 168.001 1.00 2.98  ? 591 ILE A N   1 
ATOM 2833 C CA  . ILE A 1 591 ? 175.209 158.618 167.289 1.00 4.38  ? 591 ILE A CA  1 
ATOM 2834 C C   . ILE A 1 591 ? 175.696 159.175 165.942 1.00 4.39  ? 591 ILE A C   1 
ATOM 2835 O O   . ILE A 1 591 ? 175.017 158.931 164.925 1.00 2.46  ? 591 ILE A O   1 
ATOM 2836 C CB  . ILE A 1 591 ? 174.571 159.716 168.160 1.00 3.59  ? 591 ILE A CB  1 
ATOM 2837 C CG1 . ILE A 1 591 ? 173.911 159.133 169.410 1.00 5.10  ? 591 ILE A CG1 1 
ATOM 2838 C CG2 . ILE A 1 591 ? 173.593 160.556 167.340 1.00 5.39  ? 591 ILE A CG2 1 
ATOM 2839 C CD1 . ILE A 1 591 ? 173.496 160.171 170.437 1.00 4.79  ? 591 ILE A CD1 1 
ATOM 2840 N N   . ILE A 1 592 ? 176.813 159.907 165.948 1.00 3.26  ? 592 ILE A N   1 
ATOM 2841 C CA  . ILE A 1 592 ? 177.368 160.483 164.687 1.00 4.32  ? 592 ILE A CA  1 
ATOM 2842 C C   . ILE A 1 592 ? 177.315 159.403 163.597 1.00 2.35  ? 592 ILE A C   1 
ATOM 2843 O O   . ILE A 1 592 ? 176.728 159.669 162.527 1.00 3.57  ? 592 ILE A O   1 
ATOM 2844 C CB  . ILE A 1 592 ? 178.803 160.991 164.907 1.00 7.41  ? 592 ILE A CB  1 
ATOM 2845 C CG1 . ILE A 1 592 ? 178.870 161.987 166.061 1.00 5.31  ? 592 ILE A CG1 1 
ATOM 2846 C CG2 . ILE A 1 592 ? 179.383 161.575 163.618 1.00 2.87  ? 592 ILE A CG2 1 
ATOM 2847 C CD1 . ILE A 1 592 ? 180.066 162.917 166.005 1.00 3.54  ? 592 ILE A CD1 1 
ATOM 2848 N N   . ALA A 1 593 ? 177.899 158.233 163.868 1.00 5.70  ? 593 ALA A N   1 
ATOM 2849 C CA  . ALA A 1 593 ? 177.925 157.163 162.874 1.00 0.95  ? 593 ALA A CA  1 
ATOM 2850 C C   . ALA A 1 593 ? 176.520 156.807 162.398 1.00 1.42  ? 593 ALA A C   1 
ATOM 2851 O O   . ALA A 1 593 ? 176.288 156.643 161.192 1.00 2.28  ? 593 ALA A O   1 
ATOM 2852 C CB  . ALA A 1 593 ? 178.626 155.933 163.447 1.00 1.24  ? 593 ALA A CB  1 
ATOM 2853 N N   . THR A 1 594 ? 175.572 156.687 163.332 1.00 1.88  ? 594 THR A N   1 
ATOM 2854 C CA  . THR A 1 594 ? 174.201 156.343 162.971 1.00 0.52  ? 594 THR A CA  1 
ATOM 2855 C C   . THR A 1 594 ? 173.542 157.451 162.163 1.00 0.98  ? 594 THR A C   1 
ATOM 2856 O O   . THR A 1 594 ? 172.706 157.170 161.298 1.00 5.19  ? 594 THR A O   1 
ATOM 2857 C CB  . THR A 1 594 ? 173.385 156.037 164.232 1.00 3.52  ? 594 THR A CB  1 
ATOM 2858 O OG1 . THR A 1 594 ? 174.025 154.991 164.972 1.00 1.40  ? 594 THR A OG1 1 
ATOM 2859 C CG2 . THR A 1 594 ? 171.971 155.599 163.882 1.00 0.00  ? 594 THR A CG2 1 
ATOM 2860 N N   . VAL A 1 595 ? 173.888 158.710 162.433 1.00 0.52  ? 595 VAL A N   1 
ATOM 2861 C CA  . VAL A 1 595 ? 173.379 159.794 161.600 1.00 2.69  ? 595 VAL A CA  1 
ATOM 2862 C C   . VAL A 1 595 ? 174.035 159.779 160.220 1.00 2.27  ? 595 VAL A C   1 
ATOM 2863 O O   . VAL A 1 595 ? 173.361 159.950 159.198 1.00 2.00  ? 595 VAL A O   1 
ATOM 2864 C CB  . VAL A 1 595 ? 173.577 161.146 162.311 1.00 2.49  ? 595 VAL A CB  1 
ATOM 2865 C CG1 . VAL A 1 595 ? 173.445 162.293 161.323 1.00 1.02  ? 595 VAL A CG1 1 
ATOM 2866 C CG2 . VAL A 1 595 ? 172.574 161.300 163.441 1.00 0.11  ? 595 VAL A CG2 1 
ATOM 2867 N N   . PHE A 1 596 ? 175.349 159.558 160.167 1.00 1.64  ? 596 PHE A N   1 
ATOM 2868 C CA  . PHE A 1 596 ? 176.123 159.778 158.952 1.00 1.21  ? 596 PHE A CA  1 
ATOM 2869 C C   . PHE A 1 596 ? 175.985 158.650 157.936 1.00 0.00  ? 596 PHE A C   1 
ATOM 2870 O O   . PHE A 1 596 ? 176.061 158.911 156.731 1.00 1.02  ? 596 PHE A O   1 
ATOM 2871 C CB  . PHE A 1 596 ? 177.598 159.978 159.309 1.00 1.17  ? 596 PHE A CB  1 
ATOM 2872 C CG  . PHE A 1 596 ? 177.938 161.379 159.741 1.00 3.07  ? 596 PHE A CG  1 
ATOM 2873 C CD1 . PHE A 1 596 ? 176.946 162.255 160.152 1.00 3.45  ? 596 PHE A CD1 1 
ATOM 2874 C CD2 . PHE A 1 596 ? 179.251 161.819 159.742 1.00 4.32  ? 596 PHE A CD2 1 
ATOM 2875 C CE1 . PHE A 1 596 ? 177.256 163.540 160.549 1.00 0.41  ? 596 PHE A CE1 1 
ATOM 2876 C CE2 . PHE A 1 596 ? 179.566 163.106 160.137 1.00 3.82  ? 596 PHE A CE2 1 
ATOM 2877 C CZ  . PHE A 1 596 ? 178.568 163.966 160.542 1.00 0.00  ? 596 PHE A CZ  1 
ATOM 2878 N N   . ALA A 1 597 ? 175.809 157.403 158.383 1.00 0.00  ? 597 ALA A N   1 
ATOM 2879 C CA  . ALA A 1 597 ? 175.728 156.291 157.433 1.00 1.17  ? 597 ALA A CA  1 
ATOM 2880 C C   . ALA A 1 597 ? 174.593 156.443 156.424 1.00 1.08  ? 597 ALA A C   1 
ATOM 2881 O O   . ALA A 1 597 ? 174.846 156.267 155.217 1.00 0.00  ? 597 ALA A O   1 
ATOM 2882 C CB  . ALA A 1 597 ? 175.631 154.964 158.195 1.00 0.00  ? 597 ALA A CB  1 
ATOM 2883 N N   . PRO A 1 598 ? 173.350 156.756 156.815 1.00 0.91  ? 598 PRO A N   1 
ATOM 2884 C CA  . PRO A 1 598 ? 172.331 157.037 155.791 1.00 0.60  ? 598 PRO A CA  1 
ATOM 2885 C C   . PRO A 1 598 ? 172.686 158.225 154.921 1.00 0.00  ? 598 PRO A C   1 
ATOM 2886 O O   . PRO A 1 598 ? 172.345 158.238 153.734 1.00 4.17  ? 598 PRO A O   1 
ATOM 2887 C CB  . PRO A 1 598 ? 171.058 157.293 156.614 1.00 1.14  ? 598 PRO A CB  1 
ATOM 2888 C CG  . PRO A 1 598 ? 171.341 156.725 157.960 1.00 1.95  ? 598 PRO A CG  1 
ATOM 2889 C CD  . PRO A 1 598 ? 172.799 156.915 158.172 1.00 0.00  ? 598 PRO A CD  1 
ATOM 2890 N N   . LEU A 1 599 ? 173.378 159.223 155.478 1.00 0.36  ? 599 LEU A N   1 
ATOM 2891 C CA  . LEU A 1 599 ? 173.833 160.351 154.672 1.00 2.03  ? 599 LEU A CA  1 
ATOM 2892 C C   . LEU A 1 599 ? 174.850 159.909 153.626 1.00 0.88  ? 599 LEU A C   1 
ATOM 2893 O O   . LEU A 1 599 ? 174.832 160.397 152.492 1.00 0.00  ? 599 LEU A O   1 
ATOM 2894 C CB  . LEU A 1 599 ? 174.418 161.440 155.571 1.00 0.00  ? 599 LEU A CB  1 
ATOM 2895 C CG  . LEU A 1 599 ? 173.423 162.231 156.424 1.00 0.51  ? 599 LEU A CG  1 
ATOM 2896 C CD1 . LEU A 1 599 ? 174.136 163.292 157.248 1.00 0.15  ? 599 LEU A CD1 1 
ATOM 2897 C CD2 . LEU A 1 599 ? 172.340 162.855 155.557 1.00 0.90  ? 599 LEU A CD2 1 
ATOM 2898 N N   . GLU A 1 600 ? 175.749 158.989 153.985 1.00 0.00  ? 600 GLU A N   1 
ATOM 2899 C CA  . GLU A 1 600 ? 176.707 158.486 153.003 1.00 1.80  ? 600 GLU A CA  1 
ATOM 2900 C C   . GLU A 1 600 ? 176.016 157.642 151.937 1.00 5.01  ? 600 GLU A C   1 
ATOM 2901 O O   . GLU A 1 600 ? 176.392 157.689 150.759 1.00 0.00  ? 600 GLU A O   1 
ATOM 2902 C CB  . GLU A 1 600 ? 177.817 157.693 153.697 1.00 0.00  ? 600 GLU A CB  1 
ATOM 2903 C CG  . GLU A 1 600 ? 178.565 156.714 152.790 1.00 0.30  ? 600 GLU A CG  1 
ATOM 2904 C CD  . GLU A 1 600 ? 179.593 157.381 151.876 1.00 2.03  ? 600 GLU A CD  1 
ATOM 2905 O OE1 . GLU A 1 600 ? 179.491 158.596 151.613 1.00 1.83  ? 600 GLU A OE1 1 
ATOM 2906 O OE2 . GLU A 1 600 ? 180.508 156.674 151.407 1.00 6.24  ? 600 GLU A OE2 1 
ATOM 2907 N N   . VAL A 1 601 ? 175.001 156.866 152.327 1.00 0.00  ? 601 VAL A N   1 
ATOM 2908 C CA  . VAL A 1 601 ? 174.211 156.141 151.333 1.00 0.00  ? 601 VAL A CA  1 
ATOM 2909 C C   . VAL A 1 601 ? 173.537 157.121 150.378 1.00 0.00  ? 601 VAL A C   1 
ATOM 2910 O O   . VAL A 1 601 ? 173.497 156.901 149.161 1.00 0.00  ? 601 VAL A O   1 
ATOM 2911 C CB  . VAL A 1 601 ? 173.188 155.219 152.026 1.00 0.72  ? 601 VAL A CB  1 
ATOM 2912 C CG1 . VAL A 1 601 ? 172.267 154.569 151.002 1.00 1.67  ? 601 VAL A CG1 1 
ATOM 2913 C CG2 . VAL A 1 601 ? 173.899 154.157 152.846 1.00 0.00  ? 601 VAL A CG2 1 
ATOM 2914 N N   . PHE A 1 602 ? 173.015 158.226 150.916 1.00 0.00  ? 602 PHE A N   1 
ATOM 2915 C CA  . PHE A 1 602 ? 172.423 159.269 150.083 1.00 0.60  ? 602 PHE A CA  1 
ATOM 2916 C C   . PHE A 1 602 ? 173.458 159.892 149.148 1.00 0.00  ? 602 PHE A C   1 
ATOM 2917 O O   . PHE A 1 602 ? 173.155 160.201 147.988 1.00 0.00  ? 602 PHE A O   1 
ATOM 2918 C CB  . PHE A 1 602 ? 171.783 160.332 150.979 1.00 0.00  ? 602 PHE A CB  1 
ATOM 2919 C CG  . PHE A 1 602 ? 171.226 161.507 150.233 1.00 0.00  ? 602 PHE A CG  1 
ATOM 2920 C CD1 . PHE A 1 602 ? 169.992 161.428 149.612 1.00 2.32  ? 602 PHE A CD1 1 
ATOM 2921 C CD2 . PHE A 1 602 ? 171.933 162.694 150.158 1.00 2.62  ? 602 PHE A CD2 1 
ATOM 2922 C CE1 . PHE A 1 602 ? 169.476 162.507 148.928 1.00 0.00  ? 602 PHE A CE1 1 
ATOM 2923 C CE2 . PHE A 1 602 ? 171.423 163.777 149.474 1.00 1.74  ? 602 PHE A CE2 1 
ATOM 2924 C CZ  . PHE A 1 602 ? 170.192 163.683 148.858 1.00 1.82  ? 602 PHE A CZ  1 
ATOM 2925 N N   . ARG A 1 603 ? 174.682 160.099 149.641 1.00 0.00  ? 603 ARG A N   1 
ATOM 2926 C CA  . ARG A 1 603 ? 175.746 160.633 148.794 1.00 1.68  ? 603 ARG A CA  1 
ATOM 2927 C C   . ARG A 1 603 ? 176.077 159.681 147.651 1.00 0.00  ? 603 ARG A C   1 
ATOM 2928 O O   . ARG A 1 603 ? 176.283 160.116 146.515 1.00 0.00  ? 603 ARG A O   1 
ATOM 2929 C CB  . ARG A 1 603 ? 177.003 160.921 149.618 1.00 0.36  ? 603 ARG A CB  1 
ATOM 2930 C CG  . ARG A 1 603 ? 177.969 161.875 148.929 1.00 0.00  ? 603 ARG A CG  1 
ATOM 2931 C CD  . ARG A 1 603 ? 179.419 161.682 149.365 1.00 0.00  ? 603 ARG A CD  1 
ATOM 2932 N NE  . ARG A 1 603 ? 179.872 160.301 149.250 1.00 3.43  ? 603 ARG A NE  1 
ATOM 2933 C CZ  . ARG A 1 603 ? 180.496 159.803 148.192 1.00 0.00  ? 603 ARG A CZ  1 
ATOM 2934 N NH1 . ARG A 1 603 ? 180.730 160.539 147.118 1.00 0.00  ? 603 ARG A NH1 1 
ATOM 2935 N NH2 . ARG A 1 603 ? 180.890 158.533 148.209 1.00 0.00  ? 603 ARG A NH2 1 
ATOM 2936 N N   . ARG A 1 604 ? 176.146 158.378 147.940 1.00 0.00  ? 604 ARG A N   1 
ATOM 2937 C CA  . ARG A 1 604 ? 176.376 157.394 146.885 1.00 0.00  ? 604 ARG A CA  1 
ATOM 2938 C C   . ARG A 1 604 ? 175.228 157.393 145.882 1.00 0.00  ? 604 ARG A C   1 
ATOM 2939 O O   . ARG A 1 604 ? 175.446 157.254 144.672 1.00 0.00  ? 604 ARG A O   1 
ATOM 2940 C CB  . ARG A 1 604 ? 176.569 156.002 147.491 1.00 0.00  ? 604 ARG A CB  1 
ATOM 2941 C CG  . ARG A 1 604 ? 176.800 154.891 146.470 1.00 0.00  ? 604 ARG A CG  1 
ATOM 2942 C CD  . ARG A 1 604 ? 178.048 155.135 145.638 1.00 0.00  ? 604 ARG A CD  1 
ATOM 2943 N NE  . ARG A 1 604 ? 179.252 155.189 146.459 1.00 0.00  ? 604 ARG A NE  1 
ATOM 2944 C CZ  . ARG A 1 604 ? 180.475 155.382 145.987 1.00 0.00  ? 604 ARG A CZ  1 
ATOM 2945 N NH1 . ARG A 1 604 ? 180.699 155.540 144.692 1.00 0.00  ? 604 ARG A NH1 1 
ATOM 2946 N NH2 . ARG A 1 604 ? 181.500 155.418 146.833 1.00 0.00  ? 604 ARG A NH2 1 
ATOM 2947 N N   . PHE A 1 605 ? 173.997 157.553 146.372 1.00 0.00  ? 605 PHE A N   1 
ATOM 2948 C CA  . PHE A 1 605 ? 172.837 157.641 145.492 1.00 0.00  ? 605 PHE A CA  1 
ATOM 2949 C C   . PHE A 1 605 ? 172.938 158.842 144.552 1.00 0.00  ? 605 PHE A C   1 
ATOM 2950 O O   . PHE A 1 605 ? 172.634 158.732 143.360 1.00 0.00  ? 605 PHE A O   1 
ATOM 2951 C CB  . PHE A 1 605 ? 171.564 157.697 146.341 1.00 4.99  ? 605 PHE A CB  1 
ATOM 2952 C CG  . PHE A 1 605 ? 170.413 158.406 145.688 1.00 2.74  ? 605 PHE A CG  1 
ATOM 2953 C CD1 . PHE A 1 605 ? 169.684 157.796 144.680 1.00 0.00  ? 605 PHE A CD1 1 
ATOM 2954 C CD2 . PHE A 1 605 ? 170.041 159.676 146.103 1.00 0.00  ? 605 PHE A CD2 1 
ATOM 2955 C CE1 . PHE A 1 605 ? 168.617 158.444 144.084 1.00 0.00  ? 605 PHE A CE1 1 
ATOM 2956 C CE2 . PHE A 1 605 ? 168.975 160.331 145.512 1.00 0.81  ? 605 PHE A CE2 1 
ATOM 2957 C CZ  . PHE A 1 605 ? 168.260 159.712 144.502 1.00 0.00  ? 605 PHE A CZ  1 
ATOM 2958 N N   . VAL A 1 606 ? 173.367 159.995 145.071 1.00 0.00  ? 606 VAL A N   1 
ATOM 2959 C CA  . VAL A 1 606 ? 173.556 161.171 144.220 1.00 0.00  ? 606 VAL A CA  1 
ATOM 2960 C C   . VAL A 1 606 ? 174.704 160.946 143.239 1.00 0.00  ? 606 VAL A C   1 
ATOM 2961 O O   . VAL A 1 606 ? 174.634 161.349 142.072 1.00 0.00  ? 606 VAL A O   1 
ATOM 2962 C CB  . VAL A 1 606 ? 173.785 162.431 145.080 1.00 0.28  ? 606 VAL A CB  1 
ATOM 2963 C CG1 . VAL A 1 606 ? 174.153 163.627 144.204 1.00 0.00  ? 606 VAL A CG1 1 
ATOM 2964 C CG2 . VAL A 1 606 ? 172.556 162.743 145.914 1.00 0.20  ? 606 VAL A CG2 1 
ATOM 2965 N N   . TRP A 1 607 ? 175.775 160.297 143.701 1.00 0.00  ? 607 TRP A N   1 
ATOM 2966 C CA  . TRP A 1 607 ? 176.941 160.023 142.866 1.00 0.00  ? 607 TRP A CA  1 
ATOM 2967 C C   . TRP A 1 607 ? 176.607 159.084 141.711 1.00 0.00  ? 607 TRP A C   1 
ATOM 2968 O O   . TRP A 1 607 ? 177.224 159.172 140.642 1.00 0.00  ? 607 TRP A O   1 
ATOM 2969 C CB  . TRP A 1 607 ? 178.047 159.449 143.755 1.00 0.00  ? 607 TRP A CB  1 
ATOM 2970 C CG  . TRP A 1 607 ? 179.328 159.023 143.088 1.00 0.00  ? 607 TRP A CG  1 
ATOM 2971 C CD1 . TRP A 1 607 ? 180.483 159.745 143.001 1.00 0.00  ? 607 TRP A CD1 1 
ATOM 2972 C CD2 . TRP A 1 607 ? 179.604 157.756 142.478 1.00 0.00  ? 607 TRP A CD2 1 
ATOM 2973 N NE1 . TRP A 1 607 ? 181.448 159.020 142.350 1.00 0.00  ? 607 TRP A NE1 1 
ATOM 2974 C CE2 . TRP A 1 607 ? 180.936 157.793 142.022 1.00 0.00  ? 607 TRP A CE2 1 
ATOM 2975 C CE3 . TRP A 1 607 ? 178.851 156.597 142.265 1.00 0.00  ? 607 TRP A CE3 1 
ATOM 2976 C CZ2 . TRP A 1 607 ? 181.530 156.719 141.363 1.00 0.00  ? 607 TRP A CZ2 1 
ATOM 2977 C CZ3 . TRP A 1 607 ? 179.443 155.534 141.608 1.00 0.00  ? 607 TRP A CZ3 1 
ATOM 2978 C CH2 . TRP A 1 607 ? 180.769 155.600 141.170 1.00 0.00  ? 607 TRP A CH2 1 
ATOM 2979 N N   . ASN A 1 608 ? 175.645 158.179 141.914 1.00 0.00  ? 608 ASN A N   1 
ATOM 2980 C CA  . ASN A 1 608 ? 175.299 157.210 140.879 1.00 0.00  ? 608 ASN A CA  1 
ATOM 2981 C C   . ASN A 1 608 ? 174.780 157.894 139.616 1.00 6.50  ? 608 ASN A C   1 
ATOM 2982 O O   . ASN A 1 608 ? 175.190 157.540 138.502 1.00 3.63  ? 608 ASN A O   1 
ATOM 2983 C CB  . ASN A 1 608 ? 174.272 156.214 141.419 1.00 2.29  ? 608 ASN A CB  1 
ATOM 2984 C CG  . ASN A 1 608 ? 174.909 155.115 142.252 1.00 0.00  ? 608 ASN A CG  1 
ATOM 2985 O OD1 . ASN A 1 608 ? 176.027 154.685 141.979 1.00 0.00  ? 608 ASN A OD1 1 
ATOM 2986 N ND2 . ASN A 1 608 ? 174.198 154.657 143.272 1.00 0.00  ? 608 ASN A ND2 1 
ATOM 2987 N N   . PHE A 1 609 ? 173.896 158.887 139.773 1.00 0.79  ? 609 PHE A N   1 
ATOM 2988 C CA  . PHE A 1 609 ? 173.382 159.646 138.634 1.00 0.00  ? 609 PHE A CA  1 
ATOM 2989 C C   . PHE A 1 609 ? 174.514 160.151 137.749 1.00 0.00  ? 609 PHE A C   1 
ATOM 2990 O O   . PHE A 1 609 ? 174.598 159.819 136.561 1.00 0.00  ? 609 PHE A O   1 
ATOM 2991 C CB  . PHE A 1 609 ? 172.541 160.833 139.118 1.00 2.30  ? 609 PHE A CB  1 
ATOM 2992 C CG  . PHE A 1 609 ? 171.195 160.457 139.664 1.00 0.28  ? 609 PHE A CG  1 
ATOM 2993 C CD1 . PHE A 1 609 ? 170.302 159.720 138.906 1.00 0.00  ? 609 PHE A CD1 1 
ATOM 2994 C CD2 . PHE A 1 609 ? 170.815 160.858 140.934 1.00 3.43  ? 609 PHE A CD2 1 
ATOM 2995 C CE1 . PHE A 1 609 ? 169.062 159.380 139.406 1.00 0.00  ? 609 PHE A CE1 1 
ATOM 2996 C CE2 . PHE A 1 609 ? 169.577 160.523 141.440 1.00 0.00  ? 609 PHE A CE2 1 
ATOM 2997 C CZ  . PHE A 1 609 ? 168.699 159.781 140.677 1.00 0.13  ? 609 PHE A CZ  1 
ATOM 2998 N N   . PHE A 1 610 ? 175.408 160.950 138.328 1.00 5.23  ? 610 PHE A N   1 
ATOM 2999 C CA  . PHE A 1 610 ? 176.393 161.661 137.528 1.00 0.00  ? 610 PHE A CA  1 
ATOM 3000 C C   . PHE A 1 610 ? 177.526 160.756 137.059 1.00 0.00  ? 610 PHE A C   1 
ATOM 3001 O O   . PHE A 1 610 ? 178.047 160.963 135.959 1.00 0.00  ? 610 PHE A O   1 
ATOM 3002 C CB  . PHE A 1 610 ? 176.914 162.866 138.311 1.00 0.00  ? 610 PHE A CB  1 
ATOM 3003 C CG  . PHE A 1 610 ? 175.829 163.824 138.723 1.00 0.70  ? 610 PHE A CG  1 
ATOM 3004 C CD1 . PHE A 1 610 ? 175.265 164.695 137.802 1.00 2.25  ? 610 PHE A CD1 1 
ATOM 3005 C CD2 . PHE A 1 610 ? 175.349 163.832 140.021 1.00 1.26  ? 610 PHE A CD2 1 
ATOM 3006 C CE1 . PHE A 1 610 ? 174.257 165.566 138.176 1.00 0.30  ? 610 PHE A CE1 1 
ATOM 3007 C CE2 . PHE A 1 610 ? 174.340 164.696 140.396 1.00 1.09  ? 610 PHE A CE2 1 
ATOM 3008 C CZ  . PHE A 1 610 ? 173.796 165.567 139.475 1.00 0.00  ? 610 PHE A CZ  1 
ATOM 3009 N N   . ARG A 1 611 ? 177.897 159.730 137.832 1.00 3.62  ? 611 ARG A N   1 
ATOM 3010 C CA  . ARG A 1 611 ? 178.871 158.768 137.326 1.00 0.09  ? 611 ARG A CA  1 
ATOM 3011 C C   . ARG A 1 611 ? 178.320 158.001 136.128 1.00 3.71  ? 611 ARG A C   1 
ATOM 3012 O O   . ARG A 1 611 ? 179.018 157.832 135.121 1.00 0.00  ? 611 ARG A O   1 
ATOM 3013 C CB  . ARG A 1 611 ? 179.299 157.804 138.433 1.00 0.00  ? 611 ARG A CB  1 
ATOM 3014 C CG  . ARG A 1 611 ? 180.149 156.630 137.952 1.00 0.00  ? 611 ARG A CG  1 
ATOM 3015 C CD  . ARG A 1 611 ? 181.511 157.080 137.428 1.00 0.00  ? 611 ARG A CD  1 
ATOM 3016 N NE  . ARG A 1 611 ? 182.092 156.104 136.512 1.00 0.20  ? 611 ARG A NE  1 
ATOM 3017 C CZ  . ARG A 1 611 ? 183.334 155.644 136.586 1.00 0.57  ? 611 ARG A CZ  1 
ATOM 3018 N NH1 . ARG A 1 611 ? 184.174 156.065 137.517 1.00 1.85  ? 611 ARG A NH1 1 
ATOM 3019 N NH2 . ARG A 1 611 ? 183.743 154.736 135.705 1.00 0.00  ? 611 ARG A NH2 1 
ATOM 3020 N N   . LEU A 1 612 ? 177.065 157.544 136.206 1.00 0.00  ? 612 LEU A N   1 
ATOM 3021 C CA  . LEU A 1 612 ? 176.486 156.828 135.075 1.00 0.00  ? 612 LEU A CA  1 
ATOM 3022 C C   . LEU A 1 612 ? 176.310 157.743 133.869 1.00 0.64  ? 612 LEU A C   1 
ATOM 3023 O O   . LEU A 1 612 ? 176.499 157.310 132.728 1.00 0.00  ? 612 LEU A O   1 
ATOM 3024 C CB  . LEU A 1 612 ? 175.156 156.192 135.473 1.00 0.72  ? 612 LEU A CB  1 
ATOM 3025 C CG  . LEU A 1 612 ? 175.233 154.706 135.833 1.00 0.00  ? 612 LEU A CG  1 
ATOM 3026 C CD1 . LEU A 1 612 ? 175.734 153.894 134.646 1.00 0.00  ? 612 LEU A CD1 1 
ATOM 3027 C CD2 . LEU A 1 612 ? 176.111 154.473 137.068 1.00 0.00  ? 612 LEU A CD2 1 
ATOM 3028 N N   . GLU A 1 613 ? 175.950 159.009 134.097 1.00 2.90  ? 613 GLU A N   1 
ATOM 3029 C CA  . GLU A 1 613 ? 175.828 159.945 132.983 1.00 0.00  ? 613 GLU A CA  1 
ATOM 3030 C C   . GLU A 1 613 ? 177.178 160.201 132.319 1.00 1.06  ? 613 GLU A C   1 
ATOM 3031 O O   . GLU A 1 613 ? 177.272 160.231 131.085 1.00 1.85  ? 613 GLU A O   1 
ATOM 3032 C CB  . GLU A 1 613 ? 175.205 161.256 133.460 1.00 2.55  ? 613 GLU A CB  1 
ATOM 3033 C CG  . GLU A 1 613 ? 175.583 162.461 132.618 1.00 0.00  ? 613 GLU A CG  1 
ATOM 3034 C CD  . GLU A 1 613 ? 174.570 163.578 132.718 1.00 7.75  ? 613 GLU A CD  1 
ATOM 3035 O OE1 . GLU A 1 613 ? 173.359 163.279 132.682 1.00 13.19 ? 613 GLU A OE1 1 
ATOM 3036 O OE2 . GLU A 1 613 ? 174.979 164.752 132.835 1.00 4.84  ? 613 GLU A OE2 1 
ATOM 3037 N N   . ASN A 1 614 ? 178.236 160.387 133.117 1.00 0.06  ? 614 ASN A N   1 
ATOM 3038 C CA  . ASN A 1 614 ? 179.569 160.550 132.546 1.00 0.00  ? 614 ASN A CA  1 
ATOM 3039 C C   . ASN A 1 614 ? 179.986 159.321 131.755 1.00 0.00  ? 614 ASN A C   1 
ATOM 3040 O O   . ASN A 1 614 ? 180.594 159.439 130.686 1.00 0.00  ? 614 ASN A O   1 
ATOM 3041 C CB  . ASN A 1 614 ? 180.597 160.825 133.640 1.00 0.00  ? 614 ASN A CB  1 
ATOM 3042 C CG  . ASN A 1 614 ? 181.925 161.284 133.083 1.00 0.00  ? 614 ASN A CG  1 
ATOM 3043 O OD1 . ASN A 1 614 ? 181.987 161.930 132.038 1.00 1.68  ? 614 ASN A OD1 1 
ATOM 3044 N ND2 . ASN A 1 614 ? 183.003 160.875 133.732 1.00 0.00  ? 614 ASN A ND2 1 
ATOM 3045 N N   . GLU A 1 615 ? 179.689 158.131 132.281 1.00 0.00  ? 615 GLU A N   1 
ATOM 3046 C CA  . GLU A 1 615 ? 179.983 156.901 131.557 1.00 0.00  ? 615 GLU A CA  1 
ATOM 3047 C C   . GLU A 1 615 ? 179.228 156.848 130.236 1.00 2.74  ? 615 GLU A C   1 
ATOM 3048 O O   . GLU A 1 615 ? 179.783 156.440 129.209 1.00 1.60  ? 615 GLU A O   1 
ATOM 3049 C CB  . GLU A 1 615 ? 179.627 155.696 132.425 1.00 2.34  ? 615 GLU A CB  1 
ATOM 3050 C CG  . GLU A 1 615 ? 180.491 154.477 132.197 1.00 1.40  ? 615 GLU A CG  1 
ATOM 3051 C CD  . GLU A 1 615 ? 181.787 154.536 132.976 1.00 1.74  ? 615 GLU A CD  1 
ATOM 3052 O OE1 . GLU A 1 615 ? 182.729 155.203 132.507 1.00 0.13  ? 615 GLU A OE1 1 
ATOM 3053 O OE2 . GLU A 1 615 ? 181.863 153.918 134.055 1.00 3.36  ? 615 GLU A OE2 1 
ATOM 3054 N N   . HIS A 1 616 ? 177.956 157.249 130.248 1.00 3.39  ? 616 HIS A N   1 
ATOM 3055 C CA  . HIS A 1 616 ? 177.148 157.236 129.035 1.00 0.00  ? 616 HIS A CA  1 
ATOM 3056 C C   . HIS A 1 616 ? 177.708 158.189 127.987 1.00 2.99  ? 616 HIS A C   1 
ATOM 3057 O O   . HIS A 1 616 ? 177.781 157.852 126.800 1.00 4.51  ? 616 HIS A O   1 
ATOM 3058 C CB  . HIS A 1 616 ? 175.700 157.598 129.374 1.00 2.77  ? 616 HIS A CB  1 
ATOM 3059 C CG  . HIS A 1 616 ? 174.840 157.850 128.175 1.00 1.55  ? 616 HIS A CG  1 
ATOM 3060 N ND1 . HIS A 1 616 ? 174.267 156.833 127.443 1.00 2.02  ? 616 HIS A ND1 1 
ATOM 3061 C CD2 . HIS A 1 616 ? 174.448 159.004 127.586 1.00 5.85  ? 616 HIS A CD2 1 
ATOM 3062 C CE1 . HIS A 1 616 ? 173.563 157.349 126.453 1.00 3.58  ? 616 HIS A CE1 1 
ATOM 3063 N NE2 . HIS A 1 616 ? 173.656 158.665 126.517 1.00 5.02  ? 616 HIS A NE2 1 
ATOM 3064 N N   . LEU A 1 617 ? 178.117 159.385 128.409 1.00 3.23  ? 617 LEU A N   1 
ATOM 3065 C CA  . LEU A 1 617 ? 178.540 160.400 127.450 1.00 0.52  ? 617 LEU A CA  1 
ATOM 3066 C C   . LEU A 1 617 ? 179.984 160.197 127.007 1.00 2.24  ? 617 LEU A C   1 
ATOM 3067 O O   . LEU A 1 617 ? 180.252 159.924 125.832 1.00 7.89  ? 617 LEU A O   1 
ATOM 3068 C CB  . LEU A 1 617 ? 178.362 161.793 128.053 1.00 2.53  ? 617 LEU A CB  1 
ATOM 3069 C CG  . LEU A 1 617 ? 176.949 162.186 128.474 1.00 5.86  ? 617 LEU A CG  1 
ATOM 3070 C CD1 . LEU A 1 617 ? 177.007 163.414 129.358 1.00 3.83  ? 617 LEU A CD1 1 
ATOM 3071 C CD2 . LEU A 1 617 ? 176.076 162.431 127.256 1.00 2.50  ? 617 LEU A CD2 1 
ATOM 3072 N N   . ASN A 1 618 ? 180.931 160.316 127.936 1.00 5.36  ? 618 ASN A N   1 
ATOM 3073 C CA  . ASN A 1 618 ? 182.347 160.363 127.598 1.00 1.42  ? 618 ASN A CA  1 
ATOM 3074 C C   . ASN A 1 618 ? 183.061 159.027 127.770 1.00 0.00  ? 618 ASN A C   1 
ATOM 3075 O O   . ASN A 1 618 ? 184.263 158.949 127.499 1.00 0.00  ? 618 ASN A O   1 
ATOM 3076 C CB  . ASN A 1 618 ? 183.048 161.437 128.432 1.00 2.51  ? 618 ASN A CB  1 
ATOM 3077 C CG  . ASN A 1 618 ? 182.320 162.768 128.406 1.00 4.92  ? 618 ASN A CG  1 
ATOM 3078 O OD1 . ASN A 1 618 ? 181.545 163.083 129.309 1.00 8.63  ? 618 ASN A OD1 1 
ATOM 3079 N ND2 . ASN A 1 618 ? 182.562 163.554 127.366 1.00 6.12  ? 618 ASN A ND2 1 
ATOM 3080 N N   . ASN A 1 619 ? 182.358 157.978 128.200 1.00 3.31  ? 619 ASN A N   1 
ATOM 3081 C CA  . ASN A 1 619 ? 182.967 156.667 128.451 1.00 3.97  ? 619 ASN A CA  1 
ATOM 3082 C C   . ASN A 1 619 ? 184.161 156.798 129.400 1.00 4.10  ? 619 ASN A C   1 
ATOM 3083 O O   . ASN A 1 619 ? 185.276 156.358 129.112 1.00 5.56  ? 619 ASN A O   1 
ATOM 3084 C CB  . ASN A 1 619 ? 183.365 155.994 127.133 1.00 2.39  ? 619 ASN A CB  1 
ATOM 3085 C CG  . ASN A 1 619 ? 183.843 154.567 127.320 1.00 4.67  ? 619 ASN A CG  1 
ATOM 3086 O OD1 . ASN A 1 619 ? 183.304 153.821 128.136 1.00 8.26  ? 619 ASN A OD1 1 
ATOM 3087 N ND2 . ASN A 1 619 ? 184.858 154.180 126.558 1.00 4.55  ? 619 ASN A ND2 1 
ATOM 3088 N N   . CYS A 1 620 ? 183.909 157.423 130.554 1.00 0.19  ? 620 CYS A N   1 
ATOM 3089 C CA  . CYS A 1 620 ? 184.997 157.854 131.427 1.00 1.91  ? 620 CYS A CA  1 
ATOM 3090 C C   . CYS A 1 620 ? 185.762 156.683 132.029 1.00 1.37  ? 620 CYS A C   1 
ATOM 3091 O O   . CYS A 1 620 ? 186.929 156.834 132.406 1.00 5.08  ? 620 CYS A O   1 
ATOM 3092 C CB  . CYS A 1 620 ? 184.449 158.767 132.529 1.00 4.25  ? 620 CYS A CB  1 
ATOM 3093 S SG  . CYS A 1 620 ? 183.291 157.997 133.685 1.00 4.07  ? 620 CYS A SG  1 
ATOM 3094 N N   . GLY A 1 621 ? 185.134 155.512 132.125 1.00 2.55  ? 621 GLY A N   1 
ATOM 3095 C CA  . GLY A 1 621 ? 185.809 154.347 132.668 1.00 4.01  ? 621 GLY A CA  1 
ATOM 3096 C C   . GLY A 1 621 ? 186.694 153.591 131.700 1.00 2.50  ? 621 GLY A C   1 
ATOM 3097 O O   . GLY A 1 621 ? 187.442 152.712 132.138 1.00 3.97  ? 621 GLY A O   1 
ATOM 3098 N N   . GLU A 1 622 ? 186.629 153.913 130.405 1.00 7.02  ? 622 GLU A N   1 
ATOM 3099 C CA  . GLU A 1 622 ? 187.378 153.209 129.359 1.00 1.24  ? 622 GLU A CA  1 
ATOM 3100 C C   . GLU A 1 622 ? 187.058 151.715 129.338 1.00 5.34  ? 622 GLU A C   1 
ATOM 3101 O O   . GLU A 1 622 ? 187.907 150.890 128.995 1.00 5.97  ? 622 GLU A O   1 
ATOM 3102 C CB  . GLU A 1 622 ? 188.887 153.437 129.499 1.00 0.71  ? 622 GLU A CB  1 
ATOM 3103 C CG  . GLU A 1 622 ? 189.335 154.856 129.176 1.00 5.34  ? 622 GLU A CG  1 
ATOM 3104 C CD  . GLU A 1 622 ? 190.705 155.182 129.742 1.00 9.26  ? 622 GLU A CD  1 
ATOM 3105 O OE1 . GLU A 1 622 ? 191.331 154.285 130.343 1.00 9.30  ? 622 GLU A OE1 1 
ATOM 3106 O OE2 . GLU A 1 622 ? 191.162 156.333 129.581 1.00 13.88 ? 622 GLU A OE2 1 
ATOM 3107 N N   . PHE A 1 623 ? 185.826 151.363 129.709 1.00 1.75  ? 623 PHE A N   1 
ATOM 3108 C CA  . PHE A 1 623 ? 185.380 149.975 129.677 1.00 0.00  ? 623 PHE A CA  1 
ATOM 3109 C C   . PHE A 1 623 ? 184.788 149.590 128.327 1.00 4.62  ? 623 PHE A C   1 
ATOM 3110 O O   . PHE A 1 623 ? 184.509 148.409 128.094 1.00 12.27 ? 623 PHE A O   1 
ATOM 3111 C CB  . PHE A 1 623 ? 184.371 149.740 130.801 1.00 1.07  ? 623 PHE A CB  1 
ATOM 3112 C CG  . PHE A 1 623 ? 184.994 149.690 132.162 1.00 0.68  ? 623 PHE A CG  1 
ATOM 3113 C CD1 . PHE A 1 623 ? 185.721 148.583 132.560 1.00 3.03  ? 623 PHE A CD1 1 
ATOM 3114 C CD2 . PHE A 1 623 ? 184.919 150.776 133.013 1.00 3.53  ? 623 PHE A CD2 1 
ATOM 3115 C CE1 . PHE A 1 623 ? 186.312 148.537 133.802 1.00 2.96  ? 623 PHE A CE1 1 
ATOM 3116 C CE2 . PHE A 1 623 ? 185.525 150.741 134.245 1.00 0.27  ? 623 PHE A CE2 1 
ATOM 3117 C CZ  . PHE A 1 623 ? 186.210 149.614 134.647 1.00 0.00  ? 623 PHE A CZ  1 
ATOM 3118 N N   . ARG A 1 624 ? 184.594 150.558 127.435 1.00 5.06  ? 624 ARG A N   1 
ATOM 3119 C CA  . ARG A 1 624 ? 184.134 150.303 126.076 1.00 5.83  ? 624 ARG A CA  1 
ATOM 3120 C C   . ARG A 1 624 ? 185.319 150.407 125.123 1.00 5.90  ? 624 ARG A C   1 
ATOM 3121 O O   . ARG A 1 624 ? 186.246 151.187 125.363 1.00 7.46  ? 624 ARG A O   1 
ATOM 3122 C CB  . ARG A 1 624 ? 183.034 151.284 125.674 1.00 3.80  ? 624 ARG A CB  1 
ATOM 3123 C CG  . ARG A 1 624 ? 181.748 151.108 126.450 1.00 4.73  ? 624 ARG A CG  1 
ATOM 3124 C CD  . ARG A 1 624 ? 180.668 152.055 125.967 1.00 1.62  ? 624 ARG A CD  1 
ATOM 3125 N NE  . ARG A 1 624 ? 179.915 152.601 127.088 1.00 7.49  ? 624 ARG A NE  1 
ATOM 3126 C CZ  . ARG A 1 624 ? 179.800 153.894 127.354 1.00 5.80  ? 624 ARG A CZ  1 
ATOM 3127 N NH1 . ARG A 1 624 ? 180.327 154.813 126.562 1.00 5.06  ? 624 ARG A NH1 1 
ATOM 3128 N NH2 . ARG A 1 624 ? 179.130 154.275 128.437 1.00 6.22  ? 624 ARG A NH2 1 
ATOM 3129 N N   . ALA A 1 625 ? 185.283 149.624 124.050 1.00 8.87  ? 625 ALA A N   1 
ATOM 3130 C CA  . ALA A 1 625 ? 186.348 149.632 123.052 1.00 8.14  ? 625 ALA A CA  1 
ATOM 3131 C C   . ALA A 1 625 ? 186.207 150.825 122.111 1.00 7.68  ? 625 ALA A C   1 
ATOM 3132 O O   . ALA A 1 625 ? 185.141 151.434 122.019 1.00 13.33 ? 625 ALA A O   1 
ATOM 3133 C CB  . ALA A 1 625 ? 186.345 148.332 122.266 1.00 7.90  ? 625 ALA A CB  1 
ATOM 3134 N N   . ALA B 1 231 ? 149.019 154.372 136.448 1.00 8.82  ? 231 ALA B N   1 
ATOM 3135 C CA  . ALA B 1 231 ? 149.882 153.664 137.386 1.00 3.93  ? 231 ALA B CA  1 
ATOM 3136 C C   . ALA B 1 231 ? 149.726 154.213 138.800 1.00 3.95  ? 231 ALA B C   1 
ATOM 3137 O O   . ALA B 1 231 ? 149.790 153.465 139.775 1.00 5.01  ? 231 ALA B O   1 
ATOM 3138 C CB  . ALA B 1 231 ? 151.330 153.751 136.942 1.00 3.06  ? 231 ALA B CB  1 
ATOM 3139 N N   . TRP B 1 232 ? 149.523 155.529 138.905 1.00 0.66  ? 232 TRP B N   1 
ATOM 3140 C CA  . TRP B 1 232 ? 149.343 156.142 140.216 1.00 3.78  ? 232 TRP B CA  1 
ATOM 3141 C C   . TRP B 1 232 ? 148.063 155.662 140.888 1.00 3.52  ? 232 TRP B C   1 
ATOM 3142 O O   . TRP B 1 232 ? 148.008 155.576 142.119 1.00 2.70  ? 232 TRP B O   1 
ATOM 3143 C CB  . TRP B 1 232 ? 149.340 157.666 140.095 1.00 1.90  ? 232 TRP B CB  1 
ATOM 3144 C CG  . TRP B 1 232 ? 150.712 158.264 140.017 1.00 4.81  ? 232 TRP B CG  1 
ATOM 3145 C CD1 . TRP B 1 232 ? 151.235 158.978 138.979 1.00 5.92  ? 232 TRP B CD1 1 
ATOM 3146 C CD2 . TRP B 1 232 ? 151.738 158.202 141.018 1.00 4.07  ? 232 TRP B CD2 1 
ATOM 3147 N NE1 . TRP B 1 232 ? 152.521 159.363 139.269 1.00 6.74  ? 232 TRP B NE1 1 
ATOM 3148 C CE2 . TRP B 1 232 ? 152.854 158.898 140.514 1.00 6.87  ? 232 TRP B CE2 1 
ATOM 3149 C CE3 . TRP B 1 232 ? 151.820 157.624 142.288 1.00 2.80  ? 232 TRP B CE3 1 
ATOM 3150 C CZ2 . TRP B 1 232 ? 154.037 159.034 141.236 1.00 6.74  ? 232 TRP B CZ2 1 
ATOM 3151 C CZ3 . TRP B 1 232 ? 152.997 157.758 143.004 1.00 3.45  ? 232 TRP B CZ3 1 
ATOM 3152 C CH2 . TRP B 1 232 ? 154.089 158.459 142.476 1.00 2.08  ? 232 TRP B CH2 1 
ATOM 3153 N N   . THR B 1 233 ? 147.030 155.350 140.102 1.00 3.65  ? 233 THR B N   1 
ATOM 3154 C CA  . THR B 1 233 ? 145.796 154.813 140.669 1.00 2.75  ? 233 THR B CA  1 
ATOM 3155 C C   . THR B 1 233 ? 146.030 153.444 141.297 1.00 2.58  ? 233 THR B C   1 
ATOM 3156 O O   . THR B 1 233 ? 145.580 153.176 142.416 1.00 0.04  ? 233 THR B O   1 
ATOM 3157 C CB  . THR B 1 233 ? 144.711 154.734 139.591 1.00 5.83  ? 233 THR B CB  1 
ATOM 3158 O OG1 . THR B 1 233 ? 144.497 156.033 139.027 1.00 6.89  ? 233 THR B OG1 1 
ATOM 3159 C CG2 . THR B 1 233 ? 143.402 154.223 140.182 1.00 0.99  ? 233 THR B CG2 1 
ATOM 3160 N N   . THR B 1 234 ? 146.737 152.560 140.587 1.00 0.00  ? 234 THR B N   1 
ATOM 3161 C CA  . THR B 1 234 ? 147.042 151.242 141.135 1.00 0.95  ? 234 THR B CA  1 
ATOM 3162 C C   . THR B 1 234 ? 147.915 151.352 142.379 1.00 4.45  ? 234 THR B C   1 
ATOM 3163 O O   . THR B 1 234 ? 147.701 150.634 143.366 1.00 3.19  ? 234 THR B O   1 
ATOM 3164 C CB  . THR B 1 234 ? 147.728 150.377 140.077 1.00 0.00  ? 234 THR B CB  1 
ATOM 3165 O OG1 . THR B 1 234 ? 147.055 150.531 138.822 1.00 3.02  ? 234 THR B OG1 1 
ATOM 3166 C CG2 . THR B 1 234 ? 147.703 148.915 140.485 1.00 1.27  ? 234 THR B CG2 1 
ATOM 3167 N N   . PHE B 1 235 ? 148.907 152.246 142.349 1.00 0.00  ? 235 PHE B N   1 
ATOM 3168 C CA  . PHE B 1 235 ? 149.747 152.454 143.522 1.00 0.87  ? 235 PHE B CA  1 
ATOM 3169 C C   . PHE B 1 235 ? 148.929 152.953 144.704 1.00 0.00  ? 235 PHE B C   1 
ATOM 3170 O O   . PHE B 1 235 ? 149.125 152.499 145.835 1.00 0.00  ? 235 PHE B O   1 
ATOM 3171 C CB  . PHE B 1 235 ? 150.872 153.438 143.205 1.00 0.00  ? 235 PHE B CB  1 
ATOM 3172 C CG  . PHE B 1 235 ? 151.660 153.854 144.411 1.00 0.00  ? 235 PHE B CG  1 
ATOM 3173 C CD1 . PHE B 1 235 ? 152.624 153.016 144.944 1.00 0.95  ? 235 PHE B CD1 1 
ATOM 3174 C CD2 . PHE B 1 235 ? 151.424 155.072 145.024 1.00 0.00  ? 235 PHE B CD2 1 
ATOM 3175 C CE1 . PHE B 1 235 ? 153.347 153.390 146.059 1.00 0.00  ? 235 PHE B CE1 1 
ATOM 3176 C CE2 . PHE B 1 235 ? 152.143 155.451 146.141 1.00 0.00  ? 235 PHE B CE2 1 
ATOM 3177 C CZ  . PHE B 1 235 ? 153.106 154.608 146.658 1.00 0.00  ? 235 PHE B CZ  1 
ATOM 3178 N N   . ARG B 1 236 ? 148.018 153.898 144.464 1.00 0.75  ? 236 ARG B N   1 
ATOM 3179 C CA  . ARG B 1 236 ? 147.182 154.413 145.542 1.00 1.13  ? 236 ARG B CA  1 
ATOM 3180 C C   . ARG B 1 236 ? 146.267 153.327 146.093 1.00 1.52  ? 236 ARG B C   1 
ATOM 3181 O O   . ARG B 1 236 ? 146.039 153.255 147.305 1.00 0.00  ? 236 ARG B O   1 
ATOM 3182 C CB  . ARG B 1 236 ? 146.370 155.612 145.052 1.00 3.26  ? 236 ARG B CB  1 
ATOM 3183 C CG  . ARG B 1 236 ? 147.009 156.955 145.369 1.00 0.63  ? 236 ARG B CG  1 
ATOM 3184 C CD  . ARG B 1 236 ? 146.109 158.114 144.983 1.00 1.06  ? 236 ARG B CD  1 
ATOM 3185 N NE  . ARG B 1 236 ? 145.605 157.988 143.621 1.00 1.56  ? 236 ARG B NE  1 
ATOM 3186 C CZ  . ARG B 1 236 ? 145.907 158.815 142.629 1.00 3.34  ? 236 ARG B CZ  1 
ATOM 3187 N NH1 . ARG B 1 236 ? 146.715 159.845 142.810 1.00 4.65  ? 236 ARG B NH1 1 
ATOM 3188 N NH2 . ARG B 1 236 ? 145.386 158.600 141.425 1.00 3.76  ? 236 ARG B NH2 1 
ATOM 3189 N N   . VAL B 1 237 ? 145.734 152.473 145.216 1.00 0.00  ? 237 VAL B N   1 
ATOM 3190 C CA  . VAL B 1 237 ? 144.897 151.363 145.666 1.00 0.00  ? 237 VAL B CA  1 
ATOM 3191 C C   . VAL B 1 237 ? 145.694 150.436 146.574 1.00 1.52  ? 237 VAL B C   1 
ATOM 3192 O O   . VAL B 1 237 ? 145.240 150.060 147.661 1.00 0.08  ? 237 VAL B O   1 
ATOM 3193 C CB  . VAL B 1 237 ? 144.313 150.607 144.458 1.00 1.27  ? 237 VAL B CB  1 
ATOM 3194 C CG1 . VAL B 1 237 ? 143.845 149.219 144.869 1.00 0.26  ? 237 VAL B CG1 1 
ATOM 3195 C CG2 . VAL B 1 237 ? 143.172 151.395 143.839 1.00 0.00  ? 237 VAL B CG2 1 
ATOM 3196 N N   . GLY B 1 238 ? 146.905 150.067 146.146 1.00 1.94  ? 238 GLY B N   1 
ATOM 3197 C CA  . GLY B 1 238 ? 147.744 149.215 146.976 1.00 0.00  ? 238 GLY B CA  1 
ATOM 3198 C C   . GLY B 1 238 ? 148.106 149.859 148.302 1.00 0.00  ? 238 GLY B C   1 
ATOM 3199 O O   . GLY B 1 238 ? 148.093 149.204 149.348 1.00 0.00  ? 238 GLY B O   1 
ATOM 3200 N N   . LEU B 1 239 ? 148.432 151.152 148.274 1.00 0.00  ? 239 LEU B N   1 
ATOM 3201 C CA  . LEU B 1 239 ? 148.812 151.862 149.490 1.00 0.00  ? 239 LEU B CA  1 
ATOM 3202 C C   . LEU B 1 239 ? 147.653 151.919 150.478 1.00 0.36  ? 239 LEU B C   1 
ATOM 3203 O O   . LEU B 1 239 ? 147.822 151.640 151.674 1.00 0.00  ? 239 LEU B O   1 
ATOM 3204 C CB  . LEU B 1 239 ? 149.289 153.271 149.132 1.00 0.00  ? 239 LEU B CB  1 
ATOM 3205 C CG  . LEU B 1 239 ? 149.768 154.188 150.259 1.00 0.66  ? 239 LEU B CG  1 
ATOM 3206 C CD1 . LEU B 1 239 ? 151.206 153.878 150.639 1.00 1.58  ? 239 LEU B CD1 1 
ATOM 3207 C CD2 . LEU B 1 239 ? 149.621 155.646 149.858 1.00 0.00  ? 239 LEU B CD2 1 
ATOM 3208 N N   . PHE B 1 240 ? 146.461 152.275 149.989 1.00 3.40  ? 240 PHE B N   1 
ATOM 3209 C CA  . PHE B 1 240 ? 145.291 152.337 150.856 1.00 1.89  ? 240 PHE B CA  1 
ATOM 3210 C C   . PHE B 1 240 ? 144.938 150.958 151.394 1.00 0.00  ? 240 PHE B C   1 
ATOM 3211 O O   . PHE B 1 240 ? 144.561 150.824 152.560 1.00 0.00  ? 240 PHE B O   1 
ATOM 3212 C CB  . PHE B 1 240 ? 144.103 152.951 150.113 1.00 2.70  ? 240 PHE B CB  1 
ATOM 3213 C CG  . PHE B 1 240 ? 144.304 154.392 149.726 1.00 1.99  ? 240 PHE B CG  1 
ATOM 3214 C CD1 . PHE B 1 240 ? 145.233 155.181 150.387 1.00 1.91  ? 240 PHE B CD1 1 
ATOM 3215 C CD2 . PHE B 1 240 ? 143.565 154.956 148.700 1.00 0.00  ? 240 PHE B CD2 1 
ATOM 3216 C CE1 . PHE B 1 240 ? 145.421 156.503 150.031 1.00 1.61  ? 240 PHE B CE1 1 
ATOM 3217 C CE2 . PHE B 1 240 ? 143.747 156.278 148.339 1.00 0.77  ? 240 PHE B CE2 1 
ATOM 3218 C CZ  . PHE B 1 240 ? 144.677 157.053 149.004 1.00 2.88  ? 240 PHE B CZ  1 
ATOM 3219 N N   . CYS B 1 241 ? 145.073 149.918 150.566 1.00 0.00  ? 241 CYS B N   1 
ATOM 3220 C CA  . CYS B 1 241 ? 144.792 148.565 151.034 1.00 0.88  ? 241 CYS B CA  1 
ATOM 3221 C C   . CYS B 1 241 ? 145.756 148.142 152.137 1.00 1.88  ? 241 CYS B C   1 
ATOM 3222 O O   . CYS B 1 241 ? 145.337 147.561 153.145 1.00 0.70  ? 241 CYS B O   1 
ATOM 3223 C CB  . CYS B 1 241 ? 144.851 147.588 149.860 1.00 0.00  ? 241 CYS B CB  1 
ATOM 3224 S SG  . CYS B 1 241 ? 144.766 145.848 150.324 1.00 14.11 ? 241 CYS B SG  1 
ATOM 3225 N N   . GLY B 1 242 ? 147.050 148.427 151.970 1.00 2.78  ? 242 GLY B N   1 
ATOM 3226 C CA  . GLY B 1 242 ? 148.014 148.067 153.001 1.00 1.18  ? 242 GLY B CA  1 
ATOM 3227 C C   . GLY B 1 242 ? 147.779 148.812 154.301 1.00 0.83  ? 242 GLY B C   1 
ATOM 3228 O O   . GLY B 1 242 ? 147.794 148.220 155.390 1.00 2.59  ? 242 GLY B O   1 
ATOM 3229 N N   . ILE B 1 243 ? 147.540 150.123 154.204 1.00 0.00  ? 243 ILE B N   1 
ATOM 3230 C CA  . ILE B 1 243 ? 147.252 150.914 155.397 1.00 0.09  ? 243 ILE B CA  1 
ATOM 3231 C C   . ILE B 1 243 ? 145.989 150.406 156.079 1.00 3.48  ? 243 ILE B C   1 
ATOM 3232 O O   . ILE B 1 243 ? 145.936 150.285 157.308 1.00 2.26  ? 243 ILE B O   1 
ATOM 3233 C CB  . ILE B 1 243 ? 147.145 152.408 155.038 1.00 3.62  ? 243 ILE B CB  1 
ATOM 3234 C CG1 . ILE B 1 243 ? 148.523 152.973 154.694 1.00 1.48  ? 243 ILE B CG1 1 
ATOM 3235 C CG2 . ILE B 1 243 ? 146.518 153.195 156.178 1.00 0.00  ? 243 ILE B CG2 1 
ATOM 3236 C CD1 . ILE B 1 243 ? 148.484 154.373 154.132 1.00 3.60  ? 243 ILE B CD1 1 
ATOM 3237 N N   . PHE B 1 244 ? 144.957 150.088 155.291 1.00 2.47  ? 244 PHE B N   1 
ATOM 3238 C CA  . PHE B 1 244 ? 143.702 149.591 155.842 1.00 1.06  ? 244 PHE B CA  1 
ATOM 3239 C C   . PHE B 1 244 ? 143.893 148.257 156.552 1.00 2.60  ? 244 PHE B C   1 
ATOM 3240 O O   . PHE B 1 244 ? 143.327 148.037 157.626 1.00 4.95  ? 244 PHE B O   1 
ATOM 3241 C CB  . PHE B 1 244 ? 142.670 149.463 154.721 1.00 3.09  ? 244 PHE B CB  1 
ATOM 3242 C CG  . PHE B 1 244 ? 141.281 149.155 155.196 1.00 2.33  ? 244 PHE B CG  1 
ATOM 3243 C CD1 . PHE B 1 244 ? 140.649 149.969 156.120 1.00 3.33  ? 244 PHE B CD1 1 
ATOM 3244 C CD2 . PHE B 1 244 ? 140.598 148.054 154.706 1.00 6.64  ? 244 PHE B CD2 1 
ATOM 3245 C CE1 . PHE B 1 244 ? 139.366 149.686 156.547 1.00 1.16  ? 244 PHE B CE1 1 
ATOM 3246 C CE2 . PHE B 1 244 ? 139.316 147.768 155.131 1.00 6.57  ? 244 PHE B CE2 1 
ATOM 3247 C CZ  . PHE B 1 244 ? 138.700 148.586 156.054 1.00 1.90  ? 244 PHE B CZ  1 
ATOM 3248 N N   . ILE B 1 245 ? 144.677 147.350 155.963 1.00 0.87  ? 245 ILE B N   1 
ATOM 3249 C CA  . ILE B 1 245 ? 144.910 146.050 156.589 1.00 0.68  ? 245 ILE B CA  1 
ATOM 3250 C C   . ILE B 1 245 ? 145.627 146.225 157.922 1.00 3.93  ? 245 ILE B C   1 
ATOM 3251 O O   . ILE B 1 245 ? 145.245 145.628 158.941 1.00 3.14  ? 245 ILE B O   1 
ATOM 3252 C CB  . ILE B 1 245 ? 145.701 145.130 155.642 1.00 5.14  ? 245 ILE B CB  1 
ATOM 3253 C CG1 . ILE B 1 245 ? 144.811 144.636 154.502 1.00 4.23  ? 245 ILE B CG1 1 
ATOM 3254 C CG2 . ILE B 1 245 ? 146.296 143.953 156.404 1.00 3.27  ? 245 ILE B CG2 1 
ATOM 3255 C CD1 . ILE B 1 245 ? 145.588 144.122 153.314 1.00 3.34  ? 245 ILE B CD1 1 
ATOM 3256 N N   . VAL B 1 246 ? 146.674 147.057 157.938 1.00 1.42  ? 246 VAL B N   1 
ATOM 3257 C CA  . VAL B 1 246 ? 147.408 147.274 159.183 1.00 1.92  ? 246 VAL B CA  1 
ATOM 3258 C C   . VAL B 1 246 ? 146.506 147.918 160.231 1.00 0.59  ? 246 VAL B C   1 
ATOM 3259 O O   . VAL B 1 246 ? 146.529 147.538 161.408 1.00 0.19  ? 246 VAL B O   1 
ATOM 3260 C CB  . VAL B 1 246 ? 148.677 148.109 158.929 1.00 3.15  ? 246 VAL B CB  1 
ATOM 3261 C CG1 . VAL B 1 246 ? 149.426 148.338 160.235 1.00 2.35  ? 246 VAL B CG1 1 
ATOM 3262 C CG2 . VAL B 1 246 ? 149.578 147.411 157.925 1.00 1.66  ? 246 VAL B CG2 1 
ATOM 3263 N N   . LEU B 1 247 ? 145.690 148.893 159.823 1.00 2.49  ? 247 LEU B N   1 
ATOM 3264 C CA  . LEU B 1 247 ? 144.812 149.565 160.776 1.00 2.28  ? 247 LEU B CA  1 
ATOM 3265 C C   . LEU B 1 247 ? 143.718 148.638 161.290 1.00 1.74  ? 247 LEU B C   1 
ATOM 3266 O O   . LEU B 1 247 ? 143.301 148.763 162.442 1.00 0.00  ? 247 LEU B O   1 
ATOM 3267 C CB  . LEU B 1 247 ? 144.203 150.816 160.142 1.00 2.32  ? 247 LEU B CB  1 
ATOM 3268 C CG  . LEU B 1 247 ? 145.160 151.992 159.935 1.00 1.31  ? 247 LEU B CG  1 
ATOM 3269 C CD1 . LEU B 1 247 ? 144.402 153.257 159.562 1.00 4.13  ? 247 LEU B CD1 1 
ATOM 3270 C CD2 . LEU B 1 247 ? 146.019 152.218 161.171 1.00 0.49  ? 247 LEU B CD2 1 
ATOM 3271 N N   . ASN B 1 248 ? 143.243 147.705 160.462 1.00 4.47  ? 248 ASN B N   1 
ATOM 3272 C CA  . ASN B 1 248 ? 142.260 146.732 160.929 1.00 1.20  ? 248 ASN B CA  1 
ATOM 3273 C C   . ASN B 1 248 ? 142.873 145.772 161.940 1.00 2.27  ? 248 ASN B C   1 
ATOM 3274 O O   . ASN B 1 248 ? 142.235 145.425 162.943 1.00 6.40  ? 248 ASN B O   1 
ATOM 3275 C CB  . ASN B 1 248 ? 141.678 145.963 159.744 1.00 3.41  ? 248 ASN B CB  1 
ATOM 3276 C CG  . ASN B 1 248 ? 140.635 146.761 158.990 1.00 6.12  ? 248 ASN B CG  1 
ATOM 3277 O OD1 . ASN B 1 248 ? 139.793 147.423 159.592 1.00 4.73  ? 248 ASN B OD1 1 
ATOM 3278 N ND2 . ASN B 1 248 ? 140.684 146.699 157.665 1.00 6.68  ? 248 ASN B ND2 1 
ATOM 3279 N N   . ILE B 1 249 ? 144.109 145.330 161.693 1.00 2.96  ? 249 ILE B N   1 
ATOM 3280 C CA  . ILE B 1 249 ? 144.804 144.509 162.683 1.00 2.51  ? 249 ILE B CA  1 
ATOM 3281 C C   . ILE B 1 249 ? 144.972 145.285 163.986 1.00 3.25  ? 249 ILE B C   1 
ATOM 3282 O O   . ILE B 1 249 ? 144.768 144.747 165.085 1.00 6.45  ? 249 ILE B O   1 
ATOM 3283 C CB  . ILE B 1 249 ? 146.158 144.030 162.126 1.00 6.45  ? 249 ILE B CB  1 
ATOM 3284 C CG1 . ILE B 1 249 ? 145.944 143.108 160.924 1.00 4.07  ? 249 ILE B CG1 1 
ATOM 3285 C CG2 . ILE B 1 249 ? 146.975 143.334 163.210 1.00 5.34  ? 249 ILE B CG2 1 
ATOM 3286 C CD1 . ILE B 1 249 ? 147.162 142.293 160.550 1.00 4.36  ? 249 ILE B CD1 1 
ATOM 3287 N N   . THR B 1 250 ? 145.339 146.565 163.879 1.00 3.53  ? 250 THR B N   1 
ATOM 3288 C CA  . THR B 1 250 ? 145.477 147.408 165.062 1.00 1.36  ? 250 THR B CA  1 
ATOM 3289 C C   . THR B 1 250 ? 144.154 147.542 165.804 1.00 5.67  ? 250 THR B C   1 
ATOM 3290 O O   . THR B 1 250 ? 144.124 147.518 167.038 1.00 7.12  ? 250 THR B O   1 
ATOM 3291 C CB  . THR B 1 250 ? 146.004 148.787 164.666 1.00 2.42  ? 250 THR B CB  1 
ATOM 3292 O OG1 . THR B 1 250 ? 147.107 148.642 163.764 1.00 6.55  ? 250 THR B OG1 1 
ATOM 3293 C CG2 . THR B 1 250 ? 146.456 149.557 165.892 1.00 3.57  ? 250 THR B CG2 1 
ATOM 3294 N N   . LEU B 1 251 ? 143.051 147.702 165.069 1.00 5.87  ? 251 LEU B N   1 
ATOM 3295 C CA  . LEU B 1 251 ? 141.741 147.812 165.703 1.00 2.79  ? 251 LEU B CA  1 
ATOM 3296 C C   . LEU B 1 251 ? 141.369 146.527 166.425 1.00 2.89  ? 251 LEU B C   1 
ATOM 3297 O O   . LEU B 1 251 ? 140.810 146.569 167.525 1.00 8.15  ? 251 LEU B O   1 
ATOM 3298 C CB  . LEU B 1 251 ? 140.673 148.165 164.669 1.00 7.53  ? 251 LEU B CB  1 
ATOM 3299 C CG  . LEU B 1 251 ? 140.504 149.639 164.306 1.00 5.49  ? 251 LEU B CG  1 
ATOM 3300 C CD1 . LEU B 1 251 ? 139.735 149.765 163.007 1.00 4.13  ? 251 LEU B CD1 1 
ATOM 3301 C CD2 . LEU B 1 251 ? 139.795 150.390 165.422 1.00 2.83  ? 251 LEU B CD2 1 
ATOM 3302 N N   . VAL B 1 252 ? 141.656 145.375 165.818 1.00 3.78  ? 252 VAL B N   1 
ATOM 3303 C CA  . VAL B 1 252 ? 141.372 144.106 166.483 1.00 4.29  ? 252 VAL B CA  1 
ATOM 3304 C C   . VAL B 1 252 ? 142.164 144.000 167.780 1.00 8.12  ? 252 VAL B C   1 
ATOM 3305 O O   . VAL B 1 252 ? 141.620 143.653 168.838 1.00 9.52  ? 252 VAL B O   1 
ATOM 3306 C CB  . VAL B 1 252 ? 141.667 142.924 165.542 1.00 7.96  ? 252 VAL B CB  1 
ATOM 3307 C CG1 . VAL B 1 252 ? 141.690 141.619 166.323 1.00 5.59  ? 252 VAL B CG1 1 
ATOM 3308 C CG2 . VAL B 1 252 ? 140.630 142.862 164.433 1.00 7.35  ? 252 VAL B CG2 1 
ATOM 3309 N N   . LEU B 1 253 ? 143.461 144.322 167.722 1.00 8.52  ? 253 LEU B N   1 
ATOM 3310 C CA  . LEU B 1 253 ? 144.290 144.240 168.923 1.00 8.20  ? 253 LEU B CA  1 
ATOM 3311 C C   . LEU B 1 253 ? 143.806 145.206 170.000 1.00 7.26  ? 253 LEU B C   1 
ATOM 3312 O O   . LEU B 1 253 ? 143.732 144.845 171.182 1.00 7.36  ? 253 LEU B O   1 
ATOM 3313 C CB  . LEU B 1 253 ? 145.752 144.514 168.571 1.00 6.24  ? 253 LEU B CB  1 
ATOM 3314 C CG  . LEU B 1 253 ? 146.443 143.476 167.683 1.00 6.84  ? 253 LEU B CG  1 
ATOM 3315 C CD1 . LEU B 1 253 ? 147.952 143.619 167.766 1.00 6.52  ? 253 LEU B CD1 1 
ATOM 3316 C CD2 . LEU B 1 253 ? 146.020 142.068 168.064 1.00 7.49  ? 253 LEU B CD2 1 
ATOM 3317 N N   . ALA B 1 254 ? 143.465 146.436 169.609 1.00 3.29  ? 254 ALA B N   1 
ATOM 3318 C CA  . ALA B 1 254 ? 142.995 147.427 170.569 1.00 6.00  ? 254 ALA B CA  1 
ATOM 3319 C C   . ALA B 1 254 ? 141.666 147.017 171.189 1.00 8.95  ? 254 ALA B C   1 
ATOM 3320 O O   . ALA B 1 254 ? 141.454 147.205 172.391 1.00 10.87 ? 254 ALA B O   1 
ATOM 3321 C CB  . ALA B 1 254 ? 142.872 148.792 169.892 1.00 5.99  ? 254 ALA B CB  1 
ATOM 3322 N N   . ALA B 1 255 ? 140.757 146.461 170.386 1.00 9.19  ? 255 ALA B N   1 
ATOM 3323 C CA  . ALA B 1 255 ? 139.481 146.001 170.920 1.00 6.57  ? 255 ALA B CA  1 
ATOM 3324 C C   . ALA B 1 255 ? 139.679 144.849 171.893 1.00 7.96  ? 255 ALA B C   1 
ATOM 3325 O O   . ALA B 1 255 ? 138.970 144.752 172.901 1.00 11.69 ? 255 ALA B O   1 
ATOM 3326 C CB  . ALA B 1 255 ? 138.551 145.590 169.779 1.00 6.93  ? 255 ALA B CB  1 
ATOM 3327 N N   . VAL B 1 256 ? 140.635 143.965 171.608 1.00 10.07 ? 256 VAL B N   1 
ATOM 3328 C CA  . VAL B 1 256 ? 140.881 142.845 172.509 1.00 6.06  ? 256 VAL B CA  1 
ATOM 3329 C C   . VAL B 1 256 ? 141.511 143.323 173.815 1.00 8.48  ? 256 VAL B C   1 
ATOM 3330 O O   . VAL B 1 256 ? 141.167 142.833 174.898 1.00 12.23 ? 256 VAL B O   1 
ATOM 3331 C CB  . VAL B 1 256 ? 141.747 141.779 171.812 1.00 11.61 ? 256 VAL B CB  1 
ATOM 3332 C CG1 . VAL B 1 256 ? 142.190 140.716 172.803 1.00 6.70  ? 256 VAL B CG1 1 
ATOM 3333 C CG2 . VAL B 1 256 ? 140.977 141.141 170.668 1.00 8.68  ? 256 VAL B CG2 1 
ATOM 3334 N N   . PHE B 1 257 ? 142.446 144.275 173.713 1.00 10.21 ? 257 PHE B N   1 
ATOM 3335 C CA  . PHE B 1 257 ? 143.180 144.734 174.926 1.00 7.96  ? 257 PHE B CA  1 
ATOM 3336 C C   . PHE B 1 257 ? 142.596 146.048 175.436 1.00 12.16 ? 257 PHE B C   1 
ATOM 3337 O O   . PHE B 1 257 ? 141.845 146.021 176.430 1.00 17.01 ? 257 PHE B O   1 
ATOM 3338 C CB  . PHE B 1 257 ? 144.674 144.920 174.639 1.00 8.33  ? 257 PHE B CB  1 
ATOM 3339 C CG  . PHE B 1 257 ? 145.326 143.851 173.773 1.00 9.22  ? 257 PHE B CG  1 
ATOM 3340 C CD1 . PHE B 1 257 ? 145.059 142.502 173.977 1.00 9.49  ? 257 PHE B CD1 1 
ATOM 3341 C CD2 . PHE B 1 257 ? 146.218 144.198 172.765 1.00 9.75  ? 257 PHE B CD2 1 
ATOM 3342 C CE1 . PHE B 1 257 ? 145.656 141.534 173.185 1.00 11.19 ? 257 PHE B CE1 1 
ATOM 3343 C CE2 . PHE B 1 257 ? 146.812 143.226 171.976 1.00 8.28  ? 257 PHE B CE2 1 
ATOM 3344 C CZ  . PHE B 1 257 ? 146.530 141.897 172.188 1.00 7.37  ? 257 PHE B CZ  1 
ATOM 3345 N N   . LYS B 1 258 ? 142.914 147.165 174.776 1.00 9.64  ? 258 LYS B N   1 
ATOM 3346 C CA  . LYS B 1 258 ? 142.475 148.498 175.273 1.00 6.45  ? 258 LYS B CA  1 
ATOM 3347 C C   . LYS B 1 258 ? 140.991 148.464 175.674 1.00 12.10 ? 258 LYS B C   1 
ATOM 3348 O O   . LYS B 1 258 ? 140.674 148.935 176.789 1.00 12.34 ? 258 LYS B O   1 
ATOM 3349 C CB  . LYS B 1 258 ? 142.712 149.562 174.196 1.00 10.06 ? 258 LYS B CB  1 
ATOM 3350 C CG  . LYS B 1 258 ? 144.172 149.848 173.874 1.00 9.77  ? 258 LYS B CG  1 
ATOM 3351 C CD  . LYS B 1 258 ? 144.351 150.895 172.781 1.00 10.03 ? 258 LYS B CD  1 
ATOM 3352 C CE  . LYS B 1 258 ? 145.789 151.187 172.487 1.00 9.46  ? 258 LYS B CE  1 
ATOM 3353 N NZ  . LYS B 1 258 ? 145.940 152.177 171.418 1.00 12.16 ? 258 LYS B NZ  1 
ATOM 3354 N N   . LEU B 1 259 ? 140.121 147.931 174.812 1.00 13.04 ? 259 LEU B N   1 
ATOM 3355 C CA  . LEU B 1 259 ? 138.660 147.948 175.098 1.00 9.97  ? 259 LEU B CA  1 
ATOM 3356 C C   . LEU B 1 259 ? 138.341 147.058 176.309 1.00 11.89 ? 259 LEU B C   1 
ATOM 3357 O O   . LEU B 1 259 ? 137.414 147.418 177.068 1.00 12.38 ? 259 LEU B O   1 
ATOM 3358 C CB  . LEU B 1 259 ? 137.878 147.500 173.866 1.00 8.18  ? 259 LEU B CB  1 
ATOM 3359 C CG  . LEU B 1 259 ? 137.434 148.613 172.913 1.00 7.21  ? 259 LEU B CG  1 
ATOM 3360 C CD1 . LEU B 1 259 ? 138.645 149.240 172.246 1.00 8.69  ? 259 LEU B CD1 1 
ATOM 3361 C CD2 . LEU B 1 259 ? 136.477 148.050 171.878 1.00 10.13 ? 259 LEU B CD2 1 
ATOM 3362 N N   . GLU B 1 260 ? 139.054 145.938 176.467 1.00 9.42  ? 260 GLU B N   1 
ATOM 3363 C CA  . GLU B 1 260 ? 138.746 144.985 177.568 1.00 9.93  ? 260 GLU B CA  1 
ATOM 3364 C C   . GLU B 1 260 ? 137.267 144.580 177.465 1.00 11.71 ? 260 GLU B C   1 
ATOM 3365 O O   . GLU B 1 260 ? 136.822 144.245 176.344 1.00 12.14 ? 260 GLU B O   1 
ATOM 3366 C CB  . GLU B 1 260 ? 139.023 145.587 178.947 1.00 7.71  ? 260 GLU B CB  1 
ATOM 3367 C CG  . GLU B 1 260 ? 140.481 145.971 179.172 1.00 10.65 ? 260 GLU B CG  1 
ATOM 3368 C CD  . GLU B 1 260 ? 141.396 144.796 179.467 1.00 12.85 ? 260 GLU B CD  1 
ATOM 3369 O OE1 . GLU B 1 260 ? 142.600 144.891 179.150 1.00 11.17 ? 260 GLU B OE1 1 
ATOM 3370 O OE2 . GLU B 1 260 ? 140.905 143.787 180.014 1.00 14.64 ? 260 GLU B OE2 1 
ATOM 3371 N N   . THR B 1 261 ? 136.541 144.614 178.586 1.00 13.87 ? 261 THR B N   1 
ATOM 3372 C CA  . THR B 1 261 ? 135.101 144.270 178.585 1.00 11.73 ? 261 THR B CA  1 
ATOM 3373 C C   . THR B 1 261 ? 134.351 145.313 179.385 1.00 12.01 ? 261 THR B C   1 
ATOM 3374 O O   . THR B 1 261 ? 133.961 145.004 180.533 1.00 13.25 ? 261 THR B O   1 
ATOM 3375 C CB  . THR B 1 261 ? 134.902 142.869 179.163 1.00 10.36 ? 261 THR B CB  1 
ATOM 3376 O OG1 . THR B 1 261 ? 135.852 142.757 180.218 1.00 10.80 ? 261 THR B OG1 1 
ATOM 3377 C CG2 . THR B 1 261 ? 135.132 141.775 178.136 1.00 8.19  ? 261 THR B CG2 1 
ATOM 3378 N N   . ASP B 1 262 ? 134.156 146.507 178.816 1.00 11.32 ? 262 ASP B N   1 
ATOM 3379 C CA  . ASP B 1 262 ? 133.491 147.613 179.561 1.00 12.09 ? 262 ASP B CA  1 
ATOM 3380 C C   . ASP B 1 262 ? 132.873 148.611 178.577 1.00 9.04  ? 262 ASP B C   1 
ATOM 3381 O O   . ASP B 1 262 ? 133.142 148.463 177.363 1.00 13.33 ? 262 ASP B O   1 
ATOM 3382 C CB  . ASP B 1 262 ? 134.462 148.298 180.510 1.00 10.20 ? 262 ASP B CB  1 
ATOM 3383 C CG  . ASP B 1 262 ? 134.869 147.476 181.725 1.00 13.70 ? 262 ASP B CG  1 
ATOM 3384 O OD1 . ASP B 1 262 ? 134.188 146.467 182.004 1.00 13.83 ? 262 ASP B OD1 1 
ATOM 3385 O OD2 . ASP B 1 262 ? 135.860 147.855 182.382 1.00 14.53 ? 262 ASP B OD2 1 
ATOM 3386 N N   . ARG B 1 263 ? 132.076 149.566 179.077 1.00 10.19 ? 263 ARG B N   1 
ATOM 3387 C CA  . ARG B 1 263 ? 131.441 150.617 178.230 1.00 10.49 ? 263 ARG B CA  1 
ATOM 3388 C C   . ARG B 1 263 ? 130.257 150.042 177.432 1.00 14.38 ? 263 ARG B C   1 
ATOM 3389 O O   . ARG B 1 263 ? 130.429 148.984 176.787 1.00 12.34 ? 263 ARG B O   1 
ATOM 3390 C CB  . ARG B 1 263 ? 132.437 151.292 177.277 1.00 12.58 ? 263 ARG B CB  1 
ATOM 3391 C CG  . ARG B 1 263 ? 133.495 152.126 177.986 1.00 9.04  ? 263 ARG B CG  1 
ATOM 3392 C CD  . ARG B 1 263 ? 134.434 152.818 177.010 1.00 9.43  ? 263 ARG B CD  1 
ATOM 3393 N NE  . ARG B 1 263 ? 135.496 153.564 177.693 1.00 12.51 ? 263 ARG B NE  1 
ATOM 3394 C CZ  . ARG B 1 263 ? 136.510 154.162 177.078 1.00 11.59 ? 263 ARG B CZ  1 
ATOM 3395 N NH1 . ARG B 1 263 ? 136.994 155.297 177.549 1.00 9.88  ? 263 ARG B NH1 1 
ATOM 3396 N NH2 . ARG B 1 263 ? 137.035 153.621 175.994 1.00 14.16 ? 263 ARG B NH2 1 
ATOM 3397 N N   . SER B 1 264 ? 129.102 150.715 177.478 1.00 9.92  ? 264 SER B N   1 
ATOM 3398 C CA  . SER B 1 264 ? 127.920 150.257 176.701 1.00 7.78  ? 264 SER B CA  1 
ATOM 3399 C C   . SER B 1 264 ? 128.446 150.687 175.326 1.00 5.01  ? 264 SER B C   1 
ATOM 3400 O O   . SER B 1 264 ? 127.994 151.736 174.823 1.00 10.99 ? 264 SER B O   1 
ATOM 3401 C CB  . SER B 1 264 ? 126.579 150.875 176.992 1.00 11.70 ? 264 SER B CB  1 
ATOM 3402 O OG  . SER B 1 264 ? 126.682 152.289 177.078 1.00 6.35  ? 264 SER B OG  1 
ATOM 3403 N N   . ILE B 1 265 ? 129.371 149.913 174.755 1.00 7.00  ? 265 ILE B N   1 
ATOM 3404 C CA  . ILE B 1 265 ? 130.000 150.293 173.454 1.00 6.93  ? 265 ILE B CA  1 
ATOM 3405 C C   . ILE B 1 265 ? 128.950 150.156 172.340 1.00 10.19 ? 265 ILE B C   1 
ATOM 3406 O O   . ILE B 1 265 ? 129.192 150.680 171.230 1.00 9.23  ? 265 ILE B O   1 
ATOM 3407 C CB  . ILE B 1 265 ? 131.330 149.534 173.277 1.00 4.05  ? 265 ILE B CB  1 
ATOM 3408 C CG1 . ILE B 1 265 ? 132.378 149.959 174.307 1.00 8.44  ? 265 ILE B CG1 1 
ATOM 3409 C CG2 . ILE B 1 265 ? 131.851 149.667 171.845 1.00 5.98  ? 265 ILE B CG2 1 
ATOM 3410 C CD1 . ILE B 1 265 ? 133.603 149.064 174.344 1.00 7.99  ? 265 ILE B CD1 1 
ATOM 3411 N N   . TRP B 1 266 ? 127.817 149.502 172.619 1.00 8.32  ? 266 TRP B N   1 
ATOM 3412 C CA  . TRP B 1 266 ? 126.859 149.286 171.539 1.00 6.96  ? 266 TRP B CA  1 
ATOM 3413 C C   . TRP B 1 266 ? 126.394 150.481 170.705 1.00 8.51  ? 266 TRP B C   1 
ATOM 3414 O O   . TRP B 1 266 ? 126.225 150.333 169.486 1.00 11.79 ? 266 TRP B O   1 
ATOM 3415 C CB  . TRP B 1 266 ? 125.653 148.521 172.089 1.00 6.27  ? 266 TRP B CB  1 
ATOM 3416 C CG  . TRP B 1 266 ? 125.886 147.059 172.073 1.00 6.24  ? 266 TRP B CG  1 
ATOM 3417 C CD1 . TRP B 1 266 ? 126.101 146.249 173.147 1.00 7.87  ? 266 TRP B CD1 1 
ATOM 3418 C CD2 . TRP B 1 266 ? 125.997 146.228 170.915 1.00 7.89  ? 266 TRP B CD2 1 
ATOM 3419 N NE1 . TRP B 1 266 ? 126.307 144.958 172.731 1.00 11.73 ? 266 TRP B NE1 1 
ATOM 3420 C CE2 . TRP B 1 266 ? 126.251 144.920 171.363 1.00 7.25  ? 266 TRP B CE2 1 
ATOM 3421 C CE3 . TRP B 1 266 ? 125.892 146.463 169.539 1.00 9.06  ? 266 TRP B CE3 1 
ATOM 3422 C CZ2 . TRP B 1 266 ? 126.404 143.853 170.489 1.00 8.39  ? 266 TRP B CZ2 1 
ATOM 3423 C CZ3 . TRP B 1 266 ? 126.044 145.399 168.673 1.00 6.57  ? 266 TRP B CZ3 1 
ATOM 3424 C CH2 . TRP B 1 266 ? 126.295 144.111 169.149 1.00 7.95  ? 266 TRP B CH2 1 
ATOM 3425 N N   . PRO B 1 267 ? 126.142 151.668 171.303 1.00 3.93  ? 267 PRO B N   1 
ATOM 3426 C CA  . PRO B 1 267 ? 125.877 152.848 170.467 1.00 3.26  ? 267 PRO B CA  1 
ATOM 3427 C C   . PRO B 1 267 ? 126.983 153.089 169.453 1.00 4.44  ? 267 PRO B C   1 
ATOM 3428 O O   . PRO B 1 267 ? 126.716 153.474 168.313 1.00 2.89  ? 267 PRO B O   1 
ATOM 3429 C CB  . PRO B 1 267 ? 125.798 153.997 171.481 1.00 4.07  ? 267 PRO B CB  1 
ATOM 3430 C CG  . PRO B 1 267 ? 125.639 153.361 172.825 1.00 5.81  ? 267 PRO B CG  1 
ATOM 3431 C CD  . PRO B 1 267 ? 125.658 151.874 172.679 1.00 4.50  ? 267 PRO B CD  1 
ATOM 3432 N N   . LEU B 1 268 ? 128.231 152.849 169.862 1.00 2.76  ? 268 LEU B N   1 
ATOM 3433 C CA  . LEU B 1 268 ? 129.361 152.987 168.949 1.00 2.58  ? 268 LEU B CA  1 
ATOM 3434 C C   . LEU B 1 268 ? 129.263 152.000 167.790 1.00 4.12  ? 268 LEU B C   1 
ATOM 3435 O O   . LEU B 1 268 ? 129.540 152.353 166.635 1.00 1.69  ? 268 LEU B O   1 
ATOM 3436 C CB  . LEU B 1 268 ? 130.664 152.802 169.731 1.00 2.63  ? 268 LEU B CB  1 
ATOM 3437 C CG  . LEU B 1 268 ? 132.050 152.919 169.093 1.00 4.93  ? 268 LEU B CG  1 
ATOM 3438 C CD1 . LEU B 1 268 ? 133.066 153.199 170.181 1.00 6.97  ? 268 LEU B CD1 1 
ATOM 3439 C CD2 . LEU B 1 268 ? 132.429 151.647 168.360 1.00 3.17  ? 268 LEU B CD2 1 
ATOM 3440 N N   . ILE B 1 269 ? 128.886 150.752 168.081 1.00 3.81  ? 269 ILE B N   1 
ATOM 3441 C CA  . ILE B 1 269 ? 128.737 149.751 167.028 1.00 3.70  ? 269 ILE B CA  1 
ATOM 3442 C C   . ILE B 1 269 ? 127.650 150.171 166.048 1.00 3.94  ? 269 ILE B C   1 
ATOM 3443 O O   . ILE B 1 269 ? 127.828 150.099 164.827 1.00 2.75  ? 269 ILE B O   1 
ATOM 3444 C CB  . ILE B 1 269 ? 128.443 148.367 167.635 1.00 1.95  ? 269 ILE B CB  1 
ATOM 3445 C CG1 . ILE B 1 269 ? 129.661 147.845 168.398 1.00 3.56  ? 269 ILE B CG1 1 
ATOM 3446 C CG2 . ILE B 1 269 ? 128.029 147.385 166.549 1.00 2.50  ? 269 ILE B CG2 1 
ATOM 3447 C CD1 . ILE B 1 269 ? 129.494 146.432 168.916 1.00 3.41  ? 269 ILE B CD1 1 
ATOM 3448 N N   . ARG B 1 270 ? 126.508 150.625 166.572 1.00 2.19  ? 270 ARG B N   1 
ATOM 3449 C CA  . ARG B 1 270 ? 125.432 151.087 165.701 1.00 4.28  ? 270 ARG B CA  1 
ATOM 3450 C C   . ARG B 1 270 ? 125.859 152.292 164.873 1.00 4.21  ? 270 ARG B C   1 
ATOM 3451 O O   . ARG B 1 270 ? 125.477 152.408 163.704 1.00 10.29 ? 270 ARG B O   1 
ATOM 3452 C CB  . ARG B 1 270 ? 124.190 151.424 166.529 1.00 3.43  ? 270 ARG B CB  1 
ATOM 3453 C CG  . ARG B 1 270 ? 123.744 150.308 167.459 1.00 6.06  ? 270 ARG B CG  1 
ATOM 3454 C CD  . ARG B 1 270 ? 122.237 150.119 167.436 1.00 7.80  ? 270 ARG B CD  1 
ATOM 3455 N NE  . ARG B 1 270 ? 121.669 150.343 166.113 1.00 8.76  ? 270 ARG B NE  1 
ATOM 3456 C CZ  . ARG B 1 270 ? 120.379 150.235 165.824 1.00 6.90  ? 270 ARG B CZ  1 
ATOM 3457 N NH1 . ARG B 1 270 ? 119.491 149.902 166.746 1.00 0.84  ? 270 ARG B NH1 1 
ATOM 3458 N NH2 . ARG B 1 270 ? 119.971 150.467 164.580 1.00 1.44  ? 270 ARG B NH2 1 
ATOM 3459 N N   . ILE B 1 271 ? 126.655 153.189 165.456 1.00 0.00  ? 271 ILE B N   1 
ATOM 3460 C CA  . ILE B 1 271 ? 127.074 154.400 164.760 1.00 1.53  ? 271 ILE B CA  1 
ATOM 3461 C C   . ILE B 1 271 ? 128.052 154.080 163.634 1.00 2.59  ? 271 ILE B C   1 
ATOM 3462 O O   . ILE B 1 271 ? 127.967 154.658 162.546 1.00 6.85  ? 271 ILE B O   1 
ATOM 3463 C CB  . ILE B 1 271 ? 127.663 155.404 165.770 1.00 3.34  ? 271 ILE B CB  1 
ATOM 3464 C CG1 . ILE B 1 271 ? 126.538 156.126 166.515 1.00 3.30  ? 271 ILE B CG1 1 
ATOM 3465 C CG2 . ILE B 1 271 ? 128.572 156.405 165.084 1.00 1.35  ? 271 ILE B CG2 1 
ATOM 3466 C CD1 . ILE B 1 271 ? 127.020 157.076 167.586 1.00 2.72  ? 271 ILE B CD1 1 
ATOM 3467 N N   . TYR B 1 272 ? 128.986 153.157 163.861 1.00 0.00  ? 272 TYR B N   1 
ATOM 3468 C CA  . TYR B 1 272 ? 130.001 152.867 162.853 1.00 0.00  ? 272 TYR B CA  1 
ATOM 3469 C C   . TYR B 1 272 ? 129.595 151.764 161.877 1.00 0.25  ? 272 TYR B C   1 
ATOM 3470 O O   . TYR B 1 272 ? 130.259 151.595 160.841 1.00 1.25  ? 272 TYR B O   1 
ATOM 3471 C CB  . TYR B 1 272 ? 131.324 152.503 163.537 1.00 0.56  ? 272 TYR B CB  1 
ATOM 3472 C CG  . TYR B 1 272 ? 132.121 153.717 163.960 1.00 0.94  ? 272 TYR B CG  1 
ATOM 3473 C CD1 . TYR B 1 272 ? 131.897 154.322 165.190 1.00 0.00  ? 272 TYR B CD1 1 
ATOM 3474 C CD2 . TYR B 1 272 ? 133.080 154.272 163.123 1.00 0.63  ? 272 TYR B CD2 1 
ATOM 3475 C CE1 . TYR B 1 272 ? 132.612 155.436 165.579 1.00 0.00  ? 272 TYR B CE1 1 
ATOM 3476 C CE2 . TYR B 1 272 ? 133.802 155.385 163.503 1.00 0.51  ? 272 TYR B CE2 1 
ATOM 3477 C CZ  . TYR B 1 272 ? 133.564 155.964 164.732 1.00 1.86  ? 272 TYR B CZ  1 
ATOM 3478 O OH  . TYR B 1 272 ? 134.278 157.072 165.118 1.00 0.00  ? 272 TYR B OH  1 
ATOM 3479 N N   . ARG B 1 273 ? 128.508 151.040 162.165 1.00 1.64  ? 273 ARG B N   1 
ATOM 3480 C CA  . ARG B 1 273 ? 128.079 149.951 161.295 1.00 0.88  ? 273 ARG B CA  1 
ATOM 3481 C C   . ARG B 1 273 ? 127.701 150.454 159.907 1.00 0.54  ? 273 ARG B C   1 
ATOM 3482 O O   . ARG B 1 273 ? 128.028 149.814 158.903 1.00 0.00  ? 273 ARG B O   1 
ATOM 3483 C CB  . ARG B 1 273 ? 126.908 149.211 161.944 1.00 0.72  ? 273 ARG B CB  1 
ATOM 3484 C CG  . ARG B 1 273 ? 126.434 147.983 161.192 1.00 4.69  ? 273 ARG B CG  1 
ATOM 3485 C CD  . ARG B 1 273 ? 125.393 147.204 161.990 1.00 1.78  ? 273 ARG B CD  1 
ATOM 3486 N NE  . ARG B 1 273 ? 124.319 148.057 162.485 1.00 4.13  ? 273 ARG B NE  1 
ATOM 3487 C CZ  . ARG B 1 273 ? 123.434 147.690 163.401 1.00 3.11  ? 273 ARG B CZ  1 
ATOM 3488 N NH1 . ARG B 1 273 ? 123.468 146.488 163.953 1.00 0.00  ? 273 ARG B NH1 1 
ATOM 3489 N NH2 . ARG B 1 273 ? 122.490 148.550 163.773 1.00 2.35  ? 273 ARG B NH2 1 
ATOM 3490 N N   . GLY B 1 274 ? 127.006 151.591 159.830 1.00 2.74  ? 274 GLY B N   1 
ATOM 3491 C CA  . GLY B 1 274 ? 126.581 152.102 158.535 1.00 0.00  ? 274 GLY B CA  1 
ATOM 3492 C C   . GLY B 1 274 ? 127.741 152.497 157.641 1.00 1.30  ? 274 GLY B C   1 
ATOM 3493 O O   . GLY B 1 274 ? 127.746 152.194 156.443 1.00 1.83  ? 274 GLY B O   1 
ATOM 3494 N N   . GLY B 1 275 ? 128.737 153.182 158.206 1.00 5.64  ? 275 GLY B N   1 
ATOM 3495 C CA  . GLY B 1 275 ? 129.928 153.504 157.438 1.00 0.00  ? 275 GLY B CA  1 
ATOM 3496 C C   . GLY B 1 275 ? 130.684 152.266 157.001 1.00 0.00  ? 275 GLY B C   1 
ATOM 3497 O O   . GLY B 1 275 ? 131.163 152.186 155.862 1.00 3.26  ? 275 GLY B O   1 
ATOM 3498 N N   . PHE B 1 276 ? 130.795 151.275 157.893 1.00 0.00  ? 276 PHE B N   1 
ATOM 3499 C CA  . PHE B 1 276 ? 131.442 150.026 157.502 1.00 0.00  ? 276 PHE B CA  1 
ATOM 3500 C C   . PHE B 1 276 ? 130.703 149.368 156.340 1.00 0.00  ? 276 PHE B C   1 
ATOM 3501 O O   . PHE B 1 276 ? 131.329 148.878 155.392 1.00 0.00  ? 276 PHE B O   1 
ATOM 3502 C CB  . PHE B 1 276 ? 131.522 149.075 158.694 1.00 0.00  ? 276 PHE B CB  1 
ATOM 3503 C CG  . PHE B 1 276 ? 132.137 147.746 158.363 1.00 2.23  ? 276 PHE B CG  1 
ATOM 3504 C CD1 . PHE B 1 276 ? 133.514 147.603 158.301 1.00 0.84  ? 276 PHE B CD1 1 
ATOM 3505 C CD2 . PHE B 1 276 ? 131.342 146.641 158.110 1.00 2.93  ? 276 PHE B CD2 1 
ATOM 3506 C CE1 . PHE B 1 276 ? 134.085 146.382 157.995 1.00 1.05  ? 276 PHE B CE1 1 
ATOM 3507 C CE2 . PHE B 1 276 ? 131.908 145.417 157.804 1.00 0.82  ? 276 PHE B CE2 1 
ATOM 3508 C CZ  . PHE B 1 276 ? 133.280 145.287 157.747 1.00 1.96  ? 276 PHE B CZ  1 
ATOM 3509 N N   . LEU B 1 277 ? 129.370 149.356 156.399 1.00 0.00  ? 277 LEU B N   1 
ATOM 3510 C CA  . LEU B 1 277 ? 128.579 148.741 155.340 1.00 0.00  ? 277 LEU B CA  1 
ATOM 3511 C C   . LEU B 1 277 ? 128.727 149.495 154.024 1.00 0.00  ? 277 LEU B C   1 
ATOM 3512 O O   . LEU B 1 277 ? 128.769 148.877 152.958 1.00 0.00  ? 277 LEU B O   1 
ATOM 3513 C CB  . LEU B 1 277 ? 127.114 148.661 155.762 1.00 0.71  ? 277 LEU B CB  1 
ATOM 3514 C CG  . LEU B 1 277 ? 126.857 147.651 156.883 1.00 0.00  ? 277 LEU B CG  1 
ATOM 3515 C CD1 . LEU B 1 277 ? 125.567 147.962 157.598 1.00 1.49  ? 277 LEU B CD1 1 
ATOM 3516 C CD2 . LEU B 1 277 ? 126.850 146.225 156.353 1.00 0.00  ? 277 LEU B CD2 1 
ATOM 3517 N N   . LEU B 1 278 ? 128.810 150.827 154.074 1.00 1.52  ? 278 LEU B N   1 
ATOM 3518 C CA  . LEU B 1 278 ? 129.031 151.583 152.844 1.00 1.54  ? 278 LEU B CA  1 
ATOM 3519 C C   . LEU B 1 278 ? 130.395 151.267 152.236 1.00 2.07  ? 278 LEU B C   1 
ATOM 3520 O O   . LEU B 1 278 ? 130.522 151.134 151.010 1.00 0.00  ? 278 LEU B O   1 
ATOM 3521 C CB  . LEU B 1 278 ? 128.894 153.084 153.103 1.00 0.00  ? 278 LEU B CB  1 
ATOM 3522 C CG  . LEU B 1 278 ? 129.085 153.945 151.849 1.00 1.33  ? 278 LEU B CG  1 
ATOM 3523 C CD1 . LEU B 1 278 ? 128.087 153.558 150.765 1.00 0.74  ? 278 LEU B CD1 1 
ATOM 3524 C CD2 . LEU B 1 278 ? 128.973 155.422 152.165 1.00 3.45  ? 278 LEU B CD2 1 
ATOM 3525 N N   . ILE B 1 279 ? 131.428 151.142 153.074 1.00 0.00  ? 279 ILE B N   1 
ATOM 3526 C CA  . ILE B 1 279 ? 132.749 150.786 152.556 1.00 1.47  ? 279 ILE B CA  1 
ATOM 3527 C C   . ILE B 1 279 ? 132.724 149.397 151.922 1.00 2.27  ? 279 ILE B C   1 
ATOM 3528 O O   . ILE B 1 279 ? 133.275 149.180 150.831 1.00 2.53  ? 279 ILE B O   1 
ATOM 3529 C CB  . ILE B 1 279 ? 133.809 150.893 153.670 1.00 0.00  ? 279 ILE B CB  1 
ATOM 3530 C CG1 . ILE B 1 279 ? 134.154 152.361 153.930 1.00 0.00  ? 279 ILE B CG1 1 
ATOM 3531 C CG2 . ILE B 1 279 ? 135.065 150.122 153.298 1.00 0.09  ? 279 ILE B CG2 1 
ATOM 3532 C CD1 . ILE B 1 279 ? 134.376 152.694 155.388 1.00 0.15  ? 279 ILE B CD1 1 
ATOM 3533 N N   . GLU B 1 280 ? 132.080 148.437 152.592 1.00 0.00  ? 280 GLU B N   1 
ATOM 3534 C CA  . GLU B 1 280 ? 131.959 147.093 152.033 1.00 0.75  ? 280 GLU B CA  1 
ATOM 3535 C C   . GLU B 1 280 ? 131.195 147.111 150.713 1.00 0.00  ? 280 GLU B C   1 
ATOM 3536 O O   . GLU B 1 280 ? 131.557 146.402 149.766 1.00 1.14  ? 280 GLU B O   1 
ATOM 3537 C CB  . GLU B 1 280 ? 131.274 146.162 153.036 1.00 0.00  ? 280 GLU B CB  1 
ATOM 3538 C CG  . GLU B 1 280 ? 131.122 144.725 152.549 1.00 1.44  ? 280 GLU B CG  1 
ATOM 3539 C CD  . GLU B 1 280 ? 129.980 143.986 153.227 1.00 0.42  ? 280 GLU B CD  1 
ATOM 3540 O OE1 . GLU B 1 280 ? 129.593 144.382 154.344 1.00 2.92  ? 280 GLU B OE1 1 
ATOM 3541 O OE2 . GLU B 1 280 ? 129.477 143.000 152.652 1.00 0.54  ? 280 GLU B OE2 1 
ATOM 3542 N N   . PHE B 1 281 ? 130.133 147.916 150.637 1.00 0.00  ? 281 PHE B N   1 
ATOM 3543 C CA  . PHE B 1 281 ? 129.359 148.024 149.408 1.00 0.00  ? 281 PHE B CA  1 
ATOM 3544 C C   . PHE B 1 281 ? 130.207 148.574 148.271 1.00 2.36  ? 281 PHE B C   1 
ATOM 3545 O O   . PHE B 1 281 ? 130.142 148.074 147.146 1.00 0.00  ? 281 PHE B O   1 
ATOM 3546 C CB  . PHE B 1 281 ? 128.131 148.903 149.643 1.00 0.00  ? 281 PHE B CB  1 
ATOM 3547 C CG  . PHE B 1 281 ? 127.287 149.111 148.418 1.00 0.00  ? 281 PHE B CG  1 
ATOM 3548 C CD1 . PHE B 1 281 ? 126.600 148.054 147.844 1.00 0.00  ? 281 PHE B CD1 1 
ATOM 3549 C CD2 . PHE B 1 281 ? 127.172 150.367 147.847 1.00 0.33  ? 281 PHE B CD2 1 
ATOM 3550 C CE1 . PHE B 1 281 ? 125.819 148.243 146.718 1.00 0.00  ? 281 PHE B CE1 1 
ATOM 3551 C CE2 . PHE B 1 281 ? 126.390 150.564 146.722 1.00 2.17  ? 281 PHE B CE2 1 
ATOM 3552 C CZ  . PHE B 1 281 ? 125.712 149.500 146.157 1.00 0.00  ? 281 PHE B CZ  1 
ATOM 3553 N N   . LEU B 1 282 ? 131.013 149.602 148.546 1.00 1.70  ? 282 LEU B N   1 
ATOM 3554 C CA  . LEU B 1 282 ? 131.871 150.160 147.504 1.00 4.66  ? 282 LEU B CA  1 
ATOM 3555 C C   . LEU B 1 282 ? 132.904 149.142 147.024 1.00 0.09  ? 282 LEU B C   1 
ATOM 3556 O O   . LEU B 1 282 ? 133.141 149.006 145.815 1.00 0.09  ? 282 LEU B O   1 
ATOM 3557 C CB  . LEU B 1 282 ? 132.551 151.431 148.013 1.00 0.50  ? 282 LEU B CB  1 
ATOM 3558 C CG  . LEU B 1 282 ? 131.623 152.640 148.147 1.00 0.50  ? 282 LEU B CG  1 
ATOM 3559 C CD1 . LEU B 1 282 ? 132.288 153.761 148.928 1.00 0.00  ? 282 LEU B CD1 1 
ATOM 3560 C CD2 . LEU B 1 282 ? 131.169 153.126 146.780 1.00 0.06  ? 282 LEU B CD2 1 
ATOM 3561 N N   . PHE B 1 283 ? 133.513 148.402 147.953 1.00 1.57  ? 283 PHE B N   1 
ATOM 3562 C CA  . PHE B 1 283 ? 134.497 147.390 147.569 1.00 3.96  ? 283 PHE B CA  1 
ATOM 3563 C C   . PHE B 1 283 ? 133.860 146.287 146.719 1.00 0.00  ? 283 PHE B C   1 
ATOM 3564 O O   . PHE B 1 283 ? 134.394 145.894 145.666 1.00 0.00  ? 283 PHE B O   1 
ATOM 3565 C CB  . PHE B 1 283 ? 135.146 146.816 148.830 1.00 0.05  ? 283 PHE B CB  1 
ATOM 3566 C CG  . PHE B 1 283 ? 135.959 145.581 148.594 1.00 3.44  ? 283 PHE B CG  1 
ATOM 3567 C CD1 . PHE B 1 283 ? 137.152 145.641 147.893 1.00 3.75  ? 283 PHE B CD1 1 
ATOM 3568 C CD2 . PHE B 1 283 ? 135.542 144.358 149.094 1.00 0.18  ? 283 PHE B CD2 1 
ATOM 3569 C CE1 . PHE B 1 283 ? 137.905 144.503 147.683 1.00 4.02  ? 283 PHE B CE1 1 
ATOM 3570 C CE2 . PHE B 1 283 ? 136.293 143.216 148.888 1.00 2.13  ? 283 PHE B CE2 1 
ATOM 3571 C CZ  . PHE B 1 283 ? 137.476 143.289 148.183 1.00 2.90  ? 283 PHE B CZ  1 
ATOM 3572 N N   . LEU B 1 284 ? 132.702 145.785 147.155 1.00 1.76  ? 284 LEU B N   1 
ATOM 3573 C CA  . LEU B 1 284 ? 132.021 144.745 146.395 1.00 2.67  ? 284 LEU B CA  1 
ATOM 3574 C C   . LEU B 1 284 ? 131.518 145.269 145.056 1.00 2.78  ? 284 LEU B C   1 
ATOM 3575 O O   . LEU B 1 284 ? 131.450 144.510 144.088 1.00 0.00  ? 284 LEU B O   1 
ATOM 3576 C CB  . LEU B 1 284 ? 130.875 144.154 147.219 1.00 0.00  ? 284 LEU B CB  1 
ATOM 3577 C CG  . LEU B 1 284 ? 131.308 143.292 148.410 1.00 0.00  ? 284 LEU B CG  1 
ATOM 3578 C CD1 . LEU B 1 284 ? 130.113 142.856 149.248 1.00 0.00  ? 284 LEU B CD1 1 
ATOM 3579 C CD2 . LEU B 1 284 ? 132.114 142.083 147.950 1.00 0.00  ? 284 LEU B CD2 1 
ATOM 3580 N N   . LEU B 1 285 ? 131.186 146.559 144.970 1.00 0.00  ? 285 LEU B N   1 
ATOM 3581 C CA  . LEU B 1 285 ? 130.796 147.141 143.692 1.00 0.00  ? 285 LEU B CA  1 
ATOM 3582 C C   . LEU B 1 285 ? 131.983 147.220 142.743 1.00 5.82  ? 285 LEU B C   1 
ATOM 3583 O O   . LEU B 1 285 ? 131.828 147.056 141.528 1.00 0.00  ? 285 LEU B O   1 
ATOM 3584 C CB  . LEU B 1 285 ? 130.187 148.525 143.908 1.00 0.00  ? 285 LEU B CB  1 
ATOM 3585 C CG  . LEU B 1 285 ? 129.384 149.096 142.740 1.00 3.54  ? 285 LEU B CG  1 
ATOM 3586 C CD1 . LEU B 1 285 ? 128.242 148.160 142.368 1.00 3.50  ? 285 LEU B CD1 1 
ATOM 3587 C CD2 . LEU B 1 285 ? 128.860 150.485 143.075 1.00 3.51  ? 285 LEU B CD2 1 
ATOM 3588 N N   . GLY B 1 286 ? 133.176 147.480 143.280 1.00 3.48  ? 286 GLY B N   1 
ATOM 3589 C CA  . GLY B 1 286 ? 134.372 147.386 142.458 1.00 2.94  ? 286 GLY B CA  1 
ATOM 3590 C C   . GLY B 1 286 ? 134.569 145.990 141.896 1.00 4.79  ? 286 GLY B C   1 
ATOM 3591 O O   . GLY B 1 286 ? 134.861 145.814 140.706 1.00 0.28  ? 286 GLY B O   1 
ATOM 3592 N N   . ILE B 1 287 ? 134.389 144.976 142.744 1.00 0.00  ? 287 ILE B N   1 
ATOM 3593 C CA  . ILE B 1 287 ? 134.480 143.596 142.259 1.00 0.00  ? 287 ILE B CA  1 
ATOM 3594 C C   . ILE B 1 287 ? 133.393 143.316 141.220 1.00 6.93  ? 287 ILE B C   1 
ATOM 3595 O O   . ILE B 1 287 ? 133.628 142.618 140.224 1.00 0.00  ? 287 ILE B O   1 
ATOM 3596 C CB  . ILE B 1 287 ? 134.418 142.603 143.435 1.00 0.00  ? 287 ILE B CB  1 
ATOM 3597 C CG1 . ILE B 1 287 ? 135.577 142.847 144.404 1.00 0.31  ? 287 ILE B CG1 1 
ATOM 3598 C CG2 . ILE B 1 287 ? 134.449 141.166 142.929 1.00 0.00  ? 287 ILE B CG2 1 
ATOM 3599 C CD1 . ILE B 1 287 ? 135.682 141.813 145.498 1.00 0.61  ? 287 ILE B CD1 1 
ATOM 3600 N N   . ASN B 1 288 ? 132.192 143.863 141.434 1.00 7.16  ? 288 ASN B N   1 
ATOM 3601 C CA  . ASN B 1 288 ? 131.093 143.704 140.482 1.00 2.88  ? 288 ASN B CA  1 
ATOM 3602 C C   . ASN B 1 288 ? 131.456 144.287 139.124 1.00 0.97  ? 288 ASN B C   1 
ATOM 3603 O O   . ASN B 1 288 ? 131.198 143.676 138.082 1.00 0.00  ? 288 ASN B O   1 
ATOM 3604 C CB  . ASN B 1 288 ? 129.835 144.394 141.015 1.00 0.00  ? 288 ASN B CB  1 
ATOM 3605 C CG  . ASN B 1 288 ? 128.960 143.480 141.845 1.00 2.11  ? 288 ASN B CG  1 
ATOM 3606 O OD1 . ASN B 1 288 ? 128.400 143.903 142.854 1.00 0.84  ? 288 ASN B OD1 1 
ATOM 3607 N ND2 . ASN B 1 288 ? 128.830 142.230 141.424 1.00 0.00  ? 288 ASN B ND2 1 
ATOM 3608 N N   . THR B 1 289 ? 132.034 145.489 139.121 1.00 3.19  ? 289 THR B N   1 
ATOM 3609 C CA  . THR B 1 289 ? 132.411 146.141 137.872 1.00 1.11  ? 289 THR B CA  1 
ATOM 3610 C C   . THR B 1 289 ? 133.497 145.354 137.153 1.00 1.71  ? 289 THR B C   1 
ATOM 3611 O O   . THR B 1 289 ? 133.449 145.187 135.926 1.00 0.00  ? 289 THR B O   1 
ATOM 3612 C CB  . THR B 1 289 ? 132.872 147.574 138.151 1.00 2.11  ? 289 THR B CB  1 
ATOM 3613 O OG1 . THR B 1 289 ? 131.780 148.330 138.686 1.00 4.44  ? 289 THR B OG1 1 
ATOM 3614 C CG2 . THR B 1 289 ? 133.365 148.243 136.880 1.00 1.66  ? 289 THR B CG2 1 
ATOM 3615 N N   . TYR B 1 290 ? 134.479 144.846 137.905 1.00 1.07  ? 290 TYR B N   1 
ATOM 3616 C CA  . TYR B 1 290 ? 135.508 144.015 137.290 1.00 0.01  ? 290 TYR B CA  1 
ATOM 3617 C C   . TYR B 1 290 ? 134.905 142.764 136.661 1.00 0.63  ? 290 TYR B C   1 
ATOM 3618 O O   . TYR B 1 290 ? 135.270 142.385 135.542 1.00 0.00  ? 290 TYR B O   1 
ATOM 3619 C CB  . TYR B 1 290 ? 136.572 143.639 138.321 1.00 1.34  ? 290 TYR B CB  1 
ATOM 3620 C CG  . TYR B 1 290 ? 137.498 142.539 137.858 1.00 0.35  ? 290 TYR B CG  1 
ATOM 3621 C CD1 . TYR B 1 290 ? 138.580 142.818 137.035 1.00 2.52  ? 290 TYR B CD1 1 
ATOM 3622 C CD2 . TYR B 1 290 ? 137.288 141.220 138.238 1.00 2.26  ? 290 TYR B CD2 1 
ATOM 3623 C CE1 . TYR B 1 290 ? 139.426 141.820 136.605 1.00 4.85  ? 290 TYR B CE1 1 
ATOM 3624 C CE2 . TYR B 1 290 ? 138.129 140.212 137.811 1.00 2.47  ? 290 TYR B CE2 1 
ATOM 3625 C CZ  . TYR B 1 290 ? 139.198 140.519 136.996 1.00 6.10  ? 290 TYR B CZ  1 
ATOM 3626 O OH  . TYR B 1 290 ? 140.041 139.521 136.568 1.00 11.57 ? 290 TYR B OH  1 
ATOM 3627 N N   . GLY B 1 291 ? 133.978 142.110 137.366 1.00 2.68  ? 291 GLY B N   1 
ATOM 3628 C CA  . GLY B 1 291 ? 133.344 140.922 136.817 1.00 0.00  ? 291 GLY B CA  1 
ATOM 3629 C C   . GLY B 1 291 ? 132.505 141.216 135.587 1.00 2.26  ? 291 GLY B C   1 
ATOM 3630 O O   . GLY B 1 291 ? 132.514 140.446 134.622 1.00 1.07  ? 291 GLY B O   1 
ATOM 3631 N N   . TRP B 1 292 ? 131.769 142.331 135.607 1.00 0.32  ? 292 TRP B N   1 
ATOM 3632 C CA  . TRP B 1 292 ? 130.992 142.736 134.440 1.00 0.00  ? 292 TRP B CA  1 
ATOM 3633 C C   . TRP B 1 292 ? 131.895 142.945 133.236 1.00 1.65  ? 292 TRP B C   1 
ATOM 3634 O O   . TRP B 1 292 ? 131.605 142.463 132.135 1.00 1.56  ? 292 TRP B O   1 
ATOM 3635 C CB  . TRP B 1 292 ? 130.218 144.023 134.731 1.00 0.00  ? 292 TRP B CB  1 
ATOM 3636 C CG  . TRP B 1 292 ? 129.121 143.902 135.736 1.00 0.87  ? 292 TRP B CG  1 
ATOM 3637 C CD1 . TRP B 1 292 ? 128.431 142.777 136.076 1.00 3.48  ? 292 TRP B CD1 1 
ATOM 3638 C CD2 . TRP B 1 292 ? 128.581 144.960 136.533 1.00 0.37  ? 292 TRP B CD2 1 
ATOM 3639 N NE1 . TRP B 1 292 ? 127.498 143.069 137.040 1.00 0.00  ? 292 TRP B NE1 1 
ATOM 3640 C CE2 . TRP B 1 292 ? 127.570 144.403 137.338 1.00 1.21  ? 292 TRP B CE2 1 
ATOM 3641 C CE3 . TRP B 1 292 ? 128.859 146.326 136.646 1.00 0.00  ? 292 TRP B CE3 1 
ATOM 3642 C CZ2 . TRP B 1 292 ? 126.834 145.165 138.244 1.00 2.98  ? 292 TRP B CZ2 1 
ATOM 3643 C CZ3 . TRP B 1 292 ? 128.127 147.080 137.545 1.00 0.00  ? 292 TRP B CZ3 1 
ATOM 3644 C CH2 . TRP B 1 292 ? 127.125 146.498 138.330 1.00 0.00  ? 292 TRP B CH2 1 
ATOM 3645 N N   . ARG B 1 293 ? 132.999 143.673 133.428 1.00 5.21  ? 293 ARG B N   1 
ATOM 3646 C CA  . ARG B 1 293 ? 133.901 143.949 132.316 1.00 3.12  ? 293 ARG B CA  1 
ATOM 3647 C C   . ARG B 1 293 ? 134.550 142.671 131.796 1.00 1.51  ? 293 ARG B C   1 
ATOM 3648 O O   . ARG B 1 293 ? 134.664 142.475 130.582 1.00 3.10  ? 293 ARG B O   1 
ATOM 3649 C CB  . ARG B 1 293 ? 134.961 144.965 132.741 1.00 4.45  ? 293 ARG B CB  1 
ATOM 3650 C CG  . ARG B 1 293 ? 135.587 145.724 131.584 1.00 5.83  ? 293 ARG B CG  1 
ATOM 3651 C CD  . ARG B 1 293 ? 135.841 147.178 131.946 1.00 9.30  ? 293 ARG B CD  1 
ATOM 3652 N NE  . ARG B 1 293 ? 134.854 148.067 131.345 1.00 5.57  ? 293 ARG B NE  1 
ATOM 3653 C CZ  . ARG B 1 293 ? 134.385 149.167 131.919 1.00 7.85  ? 293 ARG B CZ  1 
ATOM 3654 N NH1 . ARG B 1 293 ? 134.789 149.547 133.120 1.00 5.03  ? 293 ARG B NH1 1 
ATOM 3655 N NH2 . ARG B 1 293 ? 133.488 149.903 131.271 1.00 11.41 ? 293 ARG B NH2 1 
ATOM 3656 N N   . GLN B 1 294 ? 134.978 141.787 132.700 1.00 2.98  ? 294 GLN B N   1 
ATOM 3657 C CA  . GLN B 1 294 ? 135.622 140.548 132.272 1.00 2.94  ? 294 GLN B CA  1 
ATOM 3658 C C   . GLN B 1 294 ? 134.654 139.644 131.519 1.00 2.51  ? 294 GLN B C   1 
ATOM 3659 O O   . GLN B 1 294 ? 135.028 139.029 130.514 1.00 5.81  ? 294 GLN B O   1 
ATOM 3660 C CB  . GLN B 1 294 ? 136.211 139.820 133.477 1.00 0.00  ? 294 GLN B CB  1 
ATOM 3661 C CG  . GLN B 1 294 ? 137.520 140.406 133.967 1.00 4.40  ? 294 GLN B CG  1 
ATOM 3662 C CD  . GLN B 1 294 ? 138.530 140.591 132.851 1.00 4.63  ? 294 GLN B CD  1 
ATOM 3663 O OE1 . GLN B 1 294 ? 138.944 141.711 132.552 1.00 12.71 ? 294 GLN B OE1 1 
ATOM 3664 N NE2 . GLN B 1 294 ? 138.933 139.489 132.229 1.00 4.04  ? 294 GLN B NE2 1 
ATOM 3665 N N   . ALA B 1 295 ? 133.408 139.547 131.985 1.00 5.82  ? 295 ALA B N   1 
ATOM 3666 C CA  . ALA B 1 295 ? 132.438 138.677 131.332 1.00 0.27  ? 295 ALA B CA  1 
ATOM 3667 C C   . ALA B 1 295 ? 131.923 139.241 130.015 1.00 6.79  ? 295 ALA B C   1 
ATOM 3668 O O   . ALA B 1 295 ? 131.457 138.473 129.169 1.00 14.13 ? 295 ALA B O   1 
ATOM 3669 C CB  . ALA B 1 295 ? 131.257 138.406 132.265 1.00 0.07  ? 295 ALA B CB  1 
ATOM 3670 N N   . GLY B 1 296 ? 132.004 140.550 129.814 1.00 5.63  ? 296 GLY B N   1 
ATOM 3671 C CA  . GLY B 1 296 ? 131.453 141.170 128.632 1.00 0.00  ? 296 GLY B CA  1 
ATOM 3672 C C   . GLY B 1 296 ? 130.085 141.788 128.804 1.00 3.13  ? 296 GLY B C   1 
ATOM 3673 O O   . GLY B 1 296 ? 129.475 142.181 127.803 1.00 7.54  ? 296 GLY B O   1 
ATOM 3674 N N   . VAL B 1 297 ? 129.580 141.881 130.034 1.00 0.00  ? 297 VAL B N   1 
ATOM 3675 C CA  . VAL B 1 297 ? 128.320 142.571 130.279 1.00 0.88  ? 297 VAL B CA  1 
ATOM 3676 C C   . VAL B 1 297 ? 128.520 144.064 130.059 1.00 0.91  ? 297 VAL B C   1 
ATOM 3677 O O   . VAL B 1 297 ? 129.452 144.669 130.605 1.00 4.94  ? 297 VAL B O   1 
ATOM 3678 C CB  . VAL B 1 297 ? 127.810 142.273 131.697 1.00 3.74  ? 297 VAL B CB  1 
ATOM 3679 C CG1 . VAL B 1 297 ? 126.611 143.150 132.033 1.00 1.28  ? 297 VAL B CG1 1 
ATOM 3680 C CG2 . VAL B 1 297 ? 127.453 140.803 131.832 1.00 0.74  ? 297 VAL B CG2 1 
ATOM 3681 N N   . ASN B 1 298 ? 127.646 144.666 129.254 1.00 0.00  ? 298 ASN B N   1 
ATOM 3682 C CA  . ASN B 1 298 ? 127.786 146.067 128.865 1.00 0.16  ? 298 ASN B CA  1 
ATOM 3683 C C   . ASN B 1 298 ? 127.007 146.936 129.848 1.00 1.70  ? 298 ASN B C   1 
ATOM 3684 O O   . ASN B 1 298 ? 125.934 147.460 129.552 1.00 3.51  ? 298 ASN B O   1 
ATOM 3685 C CB  . ASN B 1 298 ? 127.321 146.269 127.428 1.00 3.35  ? 298 ASN B CB  1 
ATOM 3686 C CG  . ASN B 1 298 ? 127.776 147.591 126.853 1.00 2.08  ? 298 ASN B CG  1 
ATOM 3687 O OD1 . ASN B 1 298 ? 128.695 148.219 127.372 1.00 4.39  ? 298 ASN B OD1 1 
ATOM 3688 N ND2 . ASN B 1 298 ? 127.160 148.002 125.755 1.00 5.70  ? 298 ASN B ND2 1 
ATOM 3689 N N   . HIS B 1 299 ? 127.580 147.095 131.042 1.00 0.00  ? 299 HIS B N   1 
ATOM 3690 C CA  . HIS B 1 299 ? 126.950 147.900 132.080 1.00 0.54  ? 299 HIS B CA  1 
ATOM 3691 C C   . HIS B 1 299 ? 126.980 149.390 131.762 1.00 0.70  ? 299 HIS B C   1 
ATOM 3692 O O   . HIS B 1 299 ? 126.109 150.126 132.234 1.00 0.53  ? 299 HIS B O   1 
ATOM 3693 C CB  . HIS B 1 299 ? 127.627 147.635 133.426 1.00 0.13  ? 299 HIS B CB  1 
ATOM 3694 C CG  . HIS B 1 299 ? 129.032 148.142 133.502 1.00 0.59  ? 299 HIS B CG  1 
ATOM 3695 N ND1 . HIS B 1 299 ? 129.350 149.380 134.015 1.00 1.55  ? 299 HIS B ND1 1 
ATOM 3696 C CD2 . HIS B 1 299 ? 130.204 147.582 133.120 1.00 1.20  ? 299 HIS B CD2 1 
ATOM 3697 C CE1 . HIS B 1 299 ? 130.657 149.559 133.952 1.00 2.34  ? 299 HIS B CE1 1 
ATOM 3698 N NE2 . HIS B 1 299 ? 131.198 148.482 133.412 1.00 3.16  ? 299 HIS B NE2 1 
ATOM 3699 N N   . VAL B 1 300 ? 127.958 149.848 130.976 1.00 3.60  ? 300 VAL B N   1 
ATOM 3700 C CA  . VAL B 1 300 ? 128.016 151.260 130.605 1.00 1.21  ? 300 VAL B CA  1 
ATOM 3701 C C   . VAL B 1 300 ? 126.790 151.645 129.787 1.00 2.13  ? 300 VAL B C   1 
ATOM 3702 O O   . VAL B 1 300 ? 126.221 152.729 129.962 1.00 5.63  ? 300 VAL B O   1 
ATOM 3703 C CB  . VAL B 1 300 ? 129.326 151.562 129.852 1.00 3.00  ? 300 VAL B CB  1 
ATOM 3704 C CG1 . VAL B 1 300 ? 129.290 152.953 129.237 1.00 2.28  ? 300 VAL B CG1 1 
ATOM 3705 C CG2 . VAL B 1 300 ? 130.516 151.424 130.788 1.00 1.10  ? 300 VAL B CG2 1 
ATOM 3706 N N   . LEU B 1 301 ? 126.359 150.761 128.886 1.00 1.79  ? 301 LEU B N   1 
ATOM 3707 C CA  . LEU B 1 301 ? 125.155 151.030 128.106 1.00 5.41  ? 301 LEU B CA  1 
ATOM 3708 C C   . LEU B 1 301 ? 123.896 150.864 128.950 1.00 3.59  ? 301 LEU B C   1 
ATOM 3709 O O   . LEU B 1 301 ? 122.958 151.660 128.837 1.00 5.81  ? 301 LEU B O   1 
ATOM 3710 C CB  . LEU B 1 301 ? 125.110 150.113 126.885 1.00 0.53  ? 301 LEU B CB  1 
ATOM 3711 C CG  . LEU B 1 301 ? 123.745 149.762 126.292 1.00 1.93  ? 301 LEU B CG  1 
ATOM 3712 C CD1 . LEU B 1 301 ? 123.219 150.900 125.430 1.00 3.54  ? 301 LEU B CD1 1 
ATOM 3713 C CD2 . LEU B 1 301 ? 123.828 148.472 125.492 1.00 2.44  ? 301 LEU B CD2 1 
ATOM 3714 N N   . ILE B 1 302 ? 123.857 149.832 129.798 1.00 0.61  ? 302 ILE B N   1 
ATOM 3715 C CA  . ILE B 1 302 ? 122.666 149.566 130.602 1.00 0.67  ? 302 ILE B CA  1 
ATOM 3716 C C   . ILE B 1 302 ? 122.416 150.701 131.586 1.00 1.80  ? 302 ILE B C   1 
ATOM 3717 O O   . ILE B 1 302 ? 121.279 151.156 131.755 1.00 6.49  ? 302 ILE B O   1 
ATOM 3718 C CB  . ILE B 1 302 ? 122.801 148.206 131.314 1.00 6.12  ? 302 ILE B CB  1 
ATOM 3719 C CG1 . ILE B 1 302 ? 122.852 147.079 130.280 1.00 0.00  ? 302 ILE B CG1 1 
ATOM 3720 C CG2 . ILE B 1 302 ? 121.656 147.994 132.301 1.00 0.00  ? 302 ILE B CG2 1 
ATOM 3721 C CD1 . ILE B 1 302 ? 122.999 145.708 130.871 1.00 0.34  ? 302 ILE B CD1 1 
ATOM 3722 N N   . PHE B 1 303 ? 123.472 151.188 132.237 1.00 0.00  ? 303 PHE B N   1 
ATOM 3723 C CA  . PHE B 1 303 ? 123.374 152.324 133.146 1.00 2.74  ? 303 PHE B CA  1 
ATOM 3724 C C   . PHE B 1 303 ? 123.224 153.657 132.423 1.00 2.50  ? 303 PHE B C   1 
ATOM 3725 O O   . PHE B 1 303 ? 123.071 154.685 133.091 1.00 0.14  ? 303 PHE B O   1 
ATOM 3726 C CB  . PHE B 1 303 ? 124.602 152.377 134.063 1.00 4.26  ? 303 PHE B CB  1 
ATOM 3727 C CG  . PHE B 1 303 ? 124.504 151.483 135.267 1.00 0.36  ? 303 PHE B CG  1 
ATOM 3728 C CD1 . PHE B 1 303 ? 123.793 151.883 136.388 1.00 0.40  ? 303 PHE B CD1 1 
ATOM 3729 C CD2 . PHE B 1 303 ? 125.123 150.245 135.280 1.00 1.02  ? 303 PHE B CD2 1 
ATOM 3730 C CE1 . PHE B 1 303 ? 123.704 151.064 137.501 1.00 0.00  ? 303 PHE B CE1 1 
ATOM 3731 C CE2 . PHE B 1 303 ? 125.037 149.420 136.389 1.00 1.36  ? 303 PHE B CE2 1 
ATOM 3732 C CZ  . PHE B 1 303 ? 124.325 149.829 137.500 1.00 0.00  ? 303 PHE B CZ  1 
ATOM 3733 N N   . GLU B 1 304 ? 123.276 153.662 131.090 1.00 7.89  ? 304 GLU B N   1 
ATOM 3734 C CA  . GLU B 1 304 ? 123.158 154.875 130.276 1.00 4.19  ? 304 GLU B CA  1 
ATOM 3735 C C   . GLU B 1 304 ? 124.250 155.884 130.624 1.00 4.55  ? 304 GLU B C   1 
ATOM 3736 O O   . GLU B 1 304 ? 123.992 157.066 130.856 1.00 8.57  ? 304 GLU B O   1 
ATOM 3737 C CB  . GLU B 1 304 ? 121.768 155.500 130.415 1.00 2.80  ? 304 GLU B CB  1 
ATOM 3738 C CG  . GLU B 1 304 ? 120.644 154.635 129.880 1.00 5.30  ? 304 GLU B CG  1 
ATOM 3739 C CD  . GLU B 1 304 ? 119.676 155.407 129.007 1.00 12.06 ? 304 GLU B CD  1 
ATOM 3740 O OE1 . GLU B 1 304 ? 118.825 154.767 128.354 1.00 9.89  ? 304 GLU B OE1 1 
ATOM 3741 O OE2 . GLU B 1 304 ? 119.766 156.653 128.970 1.00 12.71 ? 304 GLU B OE2 1 
ATOM 3742 N N   . LEU B 1 305 ? 125.490 155.404 130.646 1.00 4.42  ? 305 LEU B N   1 
ATOM 3743 C CA  . LEU B 1 305 ? 126.650 156.229 130.945 1.00 2.71  ? 305 LEU B CA  1 
ATOM 3744 C C   . LEU B 1 305 ? 127.460 156.448 129.674 1.00 6.14  ? 305 LEU B C   1 
ATOM 3745 O O   . LEU B 1 305 ? 127.242 155.782 128.657 1.00 12.71 ? 305 LEU B O   1 
ATOM 3746 C CB  . LEU B 1 305 ? 127.529 155.584 132.023 1.00 5.31  ? 305 LEU B CB  1 
ATOM 3747 C CG  . LEU B 1 305 ? 126.912 155.418 133.413 1.00 2.32  ? 305 LEU B CG  1 
ATOM 3748 C CD1 . LEU B 1 305 ? 127.833 154.612 134.312 1.00 2.50  ? 305 LEU B CD1 1 
ATOM 3749 C CD2 . LEU B 1 305 ? 126.595 156.765 134.038 1.00 7.70  ? 305 LEU B CD2 1 
ATOM 3750 N N   . ASN B 1 306 ? 128.395 157.389 129.740 1.00 4.19  ? 306 ASN B N   1 
ATOM 3751 C CA  . ASN B 1 306 ? 129.197 157.727 128.575 1.00 7.17  ? 306 ASN B CA  1 
ATOM 3752 C C   . ASN B 1 306 ? 130.079 156.543 128.181 1.00 6.18  ? 306 ASN B C   1 
ATOM 3753 O O   . ASN B 1 306 ? 130.782 155.990 129.038 1.00 6.11  ? 306 ASN B O   1 
ATOM 3754 C CB  . ASN B 1 306 ? 130.069 158.951 128.862 1.00 7.89  ? 306 ASN B CB  1 
ATOM 3755 C CG  . ASN B 1 306 ? 129.335 160.018 129.647 1.00 10.28 ? 306 ASN B CG  1 
ATOM 3756 O OD1 . ASN B 1 306 ? 128.691 159.729 130.655 1.00 10.68 ? 306 ASN B OD1 1 
ATOM 3757 N ND2 . ASN B 1 306 ? 129.429 161.261 129.189 1.00 7.98  ? 306 ASN B ND2 1 
ATOM 3758 N N   . PRO B 1 307 ? 130.109 156.078 126.903 1.00 9.56  ? 307 PRO B N   1 
ATOM 3759 C CA  . PRO B 1 307 ? 130.897 154.899 126.570 1.00 6.02  ? 307 PRO B CA  1 
ATOM 3760 C C   . PRO B 1 307 ? 132.315 155.029 127.101 1.00 6.20  ? 307 PRO B C   1 
ATOM 3761 O O   . PRO B 1 307 ? 132.961 153.996 127.364 1.00 6.56  ? 307 PRO B O   1 
ATOM 3762 C CB  . PRO B 1 307 ? 130.860 154.853 125.037 1.00 4.24  ? 307 PRO B CB  1 
ATOM 3763 C CG  . PRO B 1 307 ? 129.546 155.506 124.693 1.00 5.05  ? 307 PRO B CG  1 
ATOM 3764 C CD  . PRO B 1 307 ? 129.436 156.628 125.707 1.00 4.24  ? 307 PRO B CD  1 
ATOM 3765 N N   . ARG B 1 308 ? 132.790 156.267 127.264 1.00 7.35  ? 308 ARG B N   1 
ATOM 3766 C CA  . ARG B 1 308 ? 134.187 156.496 127.717 1.00 9.13  ? 308 ARG B CA  1 
ATOM 3767 C C   . ARG B 1 308 ? 134.186 157.357 128.988 1.00 8.36  ? 308 ARG B C   1 
ATOM 3768 O O   . ARG B 1 308 ? 133.090 157.620 129.525 1.00 10.12 ? 308 ARG B O   1 
ATOM 3769 C CB  . ARG B 1 308 ? 134.983 157.177 126.599 1.00 7.09  ? 308 ARG B CB  1 
ATOM 3770 C CG  . ARG B 1 308 ? 135.198 156.300 125.373 1.00 8.58  ? 308 ARG B CG  1 
ATOM 3771 C CD  . ARG B 1 308 ? 136.031 156.971 124.290 1.00 8.85  ? 308 ARG B CD  1 
ATOM 3772 N NE  . ARG B 1 308 ? 136.180 156.153 123.081 1.00 12.52 ? 308 ARG B NE  1 
ATOM 3773 C CZ  . ARG B 1 308 ? 136.764 156.576 121.968 1.00 10.01 ? 308 ARG B CZ  1 
ATOM 3774 N NH1 . ARG B 1 308 ? 136.933 157.870 121.765 1.00 9.48  ? 308 ARG B NH1 1 
ATOM 3775 N NH2 . ARG B 1 308 ? 137.175 155.709 121.063 1.00 8.23  ? 308 ARG B NH2 1 
ATOM 3776 N N   . SER B 1 309 ? 135.370 157.779 129.445 1.00 4.05  ? 309 SER B N   1 
ATOM 3777 C CA  . SER B 1 309 ? 135.482 158.602 130.680 1.00 9.40  ? 309 SER B CA  1 
ATOM 3778 C C   . SER B 1 309 ? 134.544 158.050 131.764 1.00 11.13 ? 309 SER B C   1 
ATOM 3779 O O   . SER B 1 309 ? 133.691 158.818 132.261 1.00 12.60 ? 309 SER B O   1 
ATOM 3780 C CB  . SER B 1 309 ? 135.208 160.060 130.398 1.00 10.74 ? 309 SER B CB  1 
ATOM 3781 O OG  . SER B 1 309 ? 133.821 160.297 130.201 1.00 13.86 ? 309 SER B OG  1 
ATOM 3782 N N   . ASN B 1 310 ? 134.708 156.774 132.123 1.00 4.82  ? 310 ASN B N   1 
ATOM 3783 C CA  . ASN B 1 310 ? 133.820 156.141 133.137 1.00 5.08  ? 310 ASN B CA  1 
ATOM 3784 C C   . ASN B 1 310 ? 134.669 155.512 134.244 1.00 8.18  ? 310 ASN B C   1 
ATOM 3785 O O   . ASN B 1 310 ? 135.727 154.928 133.920 1.00 9.63  ? 310 ASN B O   1 
ATOM 3786 C CB  . ASN B 1 310 ? 132.876 155.122 132.507 1.00 8.41  ? 310 ASN B CB  1 
ATOM 3787 C CG  . ASN B 1 310 ? 133.609 153.949 131.900 1.00 5.86  ? 310 ASN B CG  1 
ATOM 3788 O OD1 . ASN B 1 310 ? 134.649 153.525 132.414 1.00 4.75  ? 310 ASN B OD1 1 
ATOM 3789 N ND2 . ASN B 1 310 ? 133.081 153.407 130.813 1.00 5.37  ? 310 ASN B ND2 1 
ATOM 3790 N N   . LEU B 1 311 ? 134.224 155.624 135.499 1.00 4.95  ? 311 LEU B N   1 
ATOM 3791 C CA  . LEU B 1 311 ? 134.941 155.022 136.614 1.00 1.86  ? 311 LEU B CA  1 
ATOM 3792 C C   . LEU B 1 311 ? 135.237 153.550 136.354 1.00 8.54  ? 311 LEU B C   1 
ATOM 3793 O O   . LEU B 1 311 ? 134.371 152.793 135.907 1.00 11.76 ? 311 LEU B O   1 
ATOM 3794 C CB  . LEU B 1 311 ? 134.138 155.164 137.907 1.00 6.73  ? 311 LEU B CB  1 
ATOM 3795 C CG  . LEU B 1 311 ? 134.259 156.498 138.646 1.00 8.22  ? 311 LEU B CG  1 
ATOM 3796 C CD1 . LEU B 1 311 ? 133.846 156.345 140.102 1.00 3.50  ? 311 LEU B CD1 1 
ATOM 3797 C CD2 . LEU B 1 311 ? 135.667 157.067 138.535 1.00 5.88  ? 311 LEU B CD2 1 
ATOM 3798 N N   . SER B 1 312 ? 136.474 153.151 136.637 1.00 5.59  ? 312 SER B N   1 
ATOM 3799 C CA  . SER B 1 312 ? 136.858 151.751 136.583 1.00 1.89  ? 312 SER B CA  1 
ATOM 3800 C C   . SER B 1 312 ? 136.789 151.134 137.979 1.00 3.72  ? 312 SER B C   1 
ATOM 3801 O O   . SER B 1 312 ? 136.494 151.805 138.971 1.00 2.41  ? 312 SER B O   1 
ATOM 3802 C CB  . SER B 1 312 ? 138.260 151.602 135.990 1.00 4.87  ? 312 SER B CB  1 
ATOM 3803 O OG  . SER B 1 312 ? 139.256 152.021 136.906 1.00 5.67  ? 312 SER B OG  1 
ATOM 3804 N N   . HIS B 1 313 ? 137.052 149.827 138.047 1.00 2.63  ? 313 HIS B N   1 
ATOM 3805 C CA  . HIS B 1 313 ? 137.017 149.143 139.336 1.00 1.17  ? 313 HIS B CA  1 
ATOM 3806 C C   . HIS B 1 313 ? 138.149 149.602 140.248 1.00 1.62  ? 313 HIS B C   1 
ATOM 3807 O O   . HIS B 1 313 ? 137.993 149.610 141.476 1.00 2.38  ? 313 HIS B O   1 
ATOM 3808 C CB  . HIS B 1 313 ? 137.058 147.627 139.129 1.00 0.00  ? 313 HIS B CB  1 
ATOM 3809 C CG  . HIS B 1 313 ? 138.312 147.132 138.478 1.00 2.30  ? 313 HIS B CG  1 
ATOM 3810 N ND1 . HIS B 1 313 ? 138.463 147.067 137.110 1.00 3.92  ? 313 HIS B ND1 1 
ATOM 3811 C CD2 . HIS B 1 313 ? 139.465 146.660 139.006 1.00 4.51  ? 313 HIS B CD2 1 
ATOM 3812 C CE1 . HIS B 1 313 ? 139.659 146.585 136.824 1.00 2.94  ? 313 HIS B CE1 1 
ATOM 3813 N NE2 . HIS B 1 313 ? 140.287 146.330 137.957 1.00 3.48  ? 313 HIS B NE2 1 
ATOM 3814 N N   . GLN B 1 314 ? 139.285 150.002 139.670 1.00 2.31  ? 314 GLN B N   1 
ATOM 3815 C CA  . GLN B 1 314 ? 140.384 150.522 140.477 1.00 1.84  ? 314 GLN B CA  1 
ATOM 3816 C C   . GLN B 1 314 ? 139.987 151.807 141.192 1.00 0.98  ? 314 GLN B C   1 
ATOM 3817 O O   . GLN B 1 314 ? 140.391 152.037 142.334 1.00 0.91  ? 314 GLN B O   1 
ATOM 3818 C CB  . GLN B 1 314 ? 141.618 150.756 139.606 1.00 1.70  ? 314 GLN B CB  1 
ATOM 3819 C CG  . GLN B 1 314 ? 141.743 149.816 138.421 1.00 2.52  ? 314 GLN B CG  1 
ATOM 3820 C CD  . GLN B 1 314 ? 142.470 148.533 138.768 1.00 8.64  ? 314 GLN B CD  1 
ATOM 3821 O OE1 . GLN B 1 314 ? 142.288 147.975 139.849 1.00 7.31  ? 314 GLN B OE1 1 
ATOM 3822 N NE2 . GLN B 1 314 ? 143.301 148.057 137.848 1.00 8.75  ? 314 GLN B NE2 1 
ATOM 3823 N N   . HIS B 1 315 ? 139.203 152.664 140.534 1.00 0.00  ? 315 HIS B N   1 
ATOM 3824 C CA  . HIS B 1 315 ? 138.768 153.901 141.176 1.00 0.00  ? 315 HIS B CA  1 
ATOM 3825 C C   . HIS B 1 315 ? 137.842 153.622 142.355 1.00 2.33  ? 315 HIS B C   1 
ATOM 3826 O O   . HIS B 1 315 ? 137.944 154.276 143.403 1.00 2.03  ? 315 HIS B O   1 
ATOM 3827 C CB  . HIS B 1 315 ? 138.091 154.808 140.151 1.00 2.32  ? 315 HIS B CB  1 
ATOM 3828 C CG  . HIS B 1 315 ? 139.016 155.298 139.083 1.00 7.28  ? 315 HIS B CG  1 
ATOM 3829 N ND1 . HIS B 1 315 ? 139.018 154.782 137.805 1.00 6.24  ? 315 HIS B ND1 1 
ATOM 3830 C CD2 . HIS B 1 315 ? 139.980 156.248 139.106 1.00 3.01  ? 315 HIS B CD2 1 
ATOM 3831 C CE1 . HIS B 1 315 ? 139.938 155.397 137.085 1.00 5.96  ? 315 HIS B CE1 1 
ATOM 3832 N NE2 . HIS B 1 315 ? 140.537 156.292 137.851 1.00 4.86  ? 315 HIS B NE2 1 
ATOM 3833 N N   . LEU B 1 316 ? 136.933 152.656 142.204 1.00 0.72  ? 316 LEU B N   1 
ATOM 3834 C CA  . LEU B 1 316 ? 136.080 152.264 143.319 1.00 2.34  ? 316 LEU B CA  1 
ATOM 3835 C C   . LEU B 1 316 ? 136.901 151.666 144.455 1.00 0.73  ? 316 LEU B C   1 
ATOM 3836 O O   . LEU B 1 316 ? 136.637 151.944 145.630 1.00 0.00  ? 316 LEU B O   1 
ATOM 3837 C CB  . LEU B 1 316 ? 135.008 151.282 142.844 1.00 1.09  ? 316 LEU B CB  1 
ATOM 3838 C CG  . LEU B 1 316 ? 133.874 151.897 142.020 1.00 1.36  ? 316 LEU B CG  1 
ATOM 3839 C CD1 . LEU B 1 316 ? 133.123 150.831 141.236 1.00 2.05  ? 316 LEU B CD1 1 
ATOM 3840 C CD2 . LEU B 1 316 ? 132.926 152.679 142.912 1.00 2.84  ? 316 LEU B CD2 1 
ATOM 3841 N N   . PHE B 1 317 ? 137.905 150.848 144.124 1.00 0.00  ? 317 PHE B N   1 
ATOM 3842 C CA  . PHE B 1 317 ? 138.800 150.325 145.154 1.00 1.98  ? 317 PHE B CA  1 
ATOM 3843 C C   . PHE B 1 317 ? 139.535 151.454 145.869 1.00 0.00  ? 317 PHE B C   1 
ATOM 3844 O O   . PHE B 1 317 ? 139.721 151.410 147.088 1.00 0.00  ? 317 PHE B O   1 
ATOM 3845 C CB  . PHE B 1 317 ? 139.799 149.341 144.541 1.00 1.82  ? 317 PHE B CB  1 
ATOM 3846 C CG  . PHE B 1 317 ? 139.182 148.048 144.078 1.00 1.49  ? 317 PHE B CG  1 
ATOM 3847 C CD1 . PHE B 1 317 ? 138.107 147.492 144.754 1.00 2.57  ? 317 PHE B CD1 1 
ATOM 3848 C CD2 . PHE B 1 317 ? 139.685 147.386 142.970 1.00 0.00  ? 317 PHE B CD2 1 
ATOM 3849 C CE1 . PHE B 1 317 ? 137.541 146.305 144.329 1.00 1.65  ? 317 PHE B CE1 1 
ATOM 3850 C CE2 . PHE B 1 317 ? 139.123 146.196 142.539 1.00 1.04  ? 317 PHE B CE2 1 
ATOM 3851 C CZ  . PHE B 1 317 ? 138.049 145.655 143.220 1.00 1.81  ? 317 PHE B CZ  1 
ATOM 3852 N N   . GLU B 1 318 ? 139.952 152.479 145.123 1.00 0.00  ? 318 GLU B N   1 
ATOM 3853 C CA  . GLU B 1 318 ? 140.649 153.618 145.714 1.00 1.52  ? 318 GLU B CA  1 
ATOM 3854 C C   . GLU B 1 318 ? 139.751 154.375 146.686 1.00 3.23  ? 318 GLU B C   1 
ATOM 3855 O O   . GLU B 1 318 ? 140.158 154.694 147.813 1.00 0.00  ? 318 GLU B O   1 
ATOM 3856 C CB  . GLU B 1 318 ? 141.143 154.545 144.603 1.00 2.70  ? 318 GLU B CB  1 
ATOM 3857 C CG  . GLU B 1 318 ? 141.784 155.832 145.083 1.00 2.95  ? 318 GLU B CG  1 
ATOM 3858 C CD  . GLU B 1 318 ? 142.711 156.436 144.046 1.00 6.32  ? 318 GLU B CD  1 
ATOM 3859 O OE1 . GLU B 1 318 ? 143.055 157.628 144.177 1.00 9.91  ? 318 GLU B OE1 1 
ATOM 3860 O OE2 . GLU B 1 318 ? 143.101 155.717 143.104 1.00 8.53  ? 318 GLU B OE2 1 
ATOM 3861 N N   . ILE B 1 319 ? 138.524 154.682 146.258 1.00 1.33  ? 319 ILE B N   1 
ATOM 3862 C CA  . ILE B 1 319 ? 137.593 155.398 147.127 1.00 0.00  ? 319 ILE B CA  1 
ATOM 3863 C C   . ILE B 1 319 ? 137.279 154.568 148.365 1.00 0.40  ? 319 ILE B C   1 
ATOM 3864 O O   . ILE B 1 319 ? 137.254 155.086 149.490 1.00 0.00  ? 319 ILE B O   1 
ATOM 3865 C CB  . ILE B 1 319 ? 136.314 155.774 146.355 1.00 1.14  ? 319 ILE B CB  1 
ATOM 3866 C CG1 . ILE B 1 319 ? 136.642 156.720 145.200 1.00 6.40  ? 319 ILE B CG1 1 
ATOM 3867 C CG2 . ILE B 1 319 ? 135.296 156.416 147.283 1.00 2.94  ? 319 ILE B CG2 1 
ATOM 3868 C CD1 . ILE B 1 319 ? 135.688 156.613 144.029 1.00 4.44  ? 319 ILE B CD1 1 
ATOM 3869 N N   . ALA B 1 320 ? 137.045 153.265 148.180 1.00 1.20  ? 320 ALA B N   1 
ATOM 3870 C CA  . ALA B 1 320 ? 136.744 152.395 149.310 1.00 0.82  ? 320 ALA B CA  1 
ATOM 3871 C C   . ALA B 1 320 ? 137.915 152.323 150.279 1.00 0.54  ? 320 ALA B C   1 
ATOM 3872 O O   . ALA B 1 320 ? 137.715 152.333 151.496 1.00 0.00  ? 320 ALA B O   1 
ATOM 3873 C CB  . ALA B 1 320 ? 136.365 150.999 148.816 1.00 0.00  ? 320 ALA B CB  1 
ATOM 3874 N N   . GLY B 1 321 ? 139.143 152.256 149.762 1.00 0.00  ? 321 GLY B N   1 
ATOM 3875 C CA  . GLY B 1 321 ? 140.303 152.228 150.636 1.00 0.00  ? 321 GLY B CA  1 
ATOM 3876 C C   . GLY B 1 321 ? 140.482 153.513 151.421 1.00 0.00  ? 321 GLY B C   1 
ATOM 3877 O O   . GLY B 1 321 ? 140.771 153.481 152.619 1.00 0.27  ? 321 GLY B O   1 
ATOM 3878 N N   . PHE B 1 322 ? 140.308 154.661 150.762 1.00 0.00  ? 322 PHE B N   1 
ATOM 3879 C CA  . PHE B 1 322 ? 140.420 155.937 151.463 1.00 0.00  ? 322 PHE B CA  1 
ATOM 3880 C C   . PHE B 1 322 ? 139.357 156.064 152.552 1.00 1.56  ? 322 PHE B C   1 
ATOM 3881 O O   . PHE B 1 322 ? 139.651 156.474 153.686 1.00 0.78  ? 322 PHE B O   1 
ATOM 3882 C CB  . PHE B 1 322 ? 140.315 157.091 150.464 1.00 0.10  ? 322 PHE B CB  1 
ATOM 3883 C CG  . PHE B 1 322 ? 140.432 158.450 151.091 1.00 1.91  ? 322 PHE B CG  1 
ATOM 3884 C CD1 . PHE B 1 322 ? 141.644 158.897 151.588 1.00 0.44  ? 322 PHE B CD1 1 
ATOM 3885 C CD2 . PHE B 1 322 ? 139.328 159.279 151.187 1.00 1.56  ? 322 PHE B CD2 1 
ATOM 3886 C CE1 . PHE B 1 322 ? 141.752 160.145 152.167 1.00 0.72  ? 322 PHE B CE1 1 
ATOM 3887 C CE2 . PHE B 1 322 ? 139.431 160.530 151.765 1.00 3.04  ? 322 PHE B CE2 1 
ATOM 3888 C CZ  . PHE B 1 322 ? 140.644 160.963 152.256 1.00 1.55  ? 322 PHE B CZ  1 
ATOM 3889 N N   . LEU B 1 323 ? 138.112 155.703 152.230 1.00 0.00  ? 323 LEU B N   1 
ATOM 3890 C CA  . LEU B 1 323 ? 137.046 155.790 153.223 1.00 0.00  ? 323 LEU B CA  1 
ATOM 3891 C C   . LEU B 1 323 ? 137.262 154.791 154.352 1.00 0.00  ? 323 LEU B C   1 
ATOM 3892 O O   . LEU B 1 323 ? 136.960 155.087 155.512 1.00 0.00  ? 323 LEU B O   1 
ATOM 3893 C CB  . LEU B 1 323 ? 135.684 155.581 152.561 1.00 0.64  ? 323 LEU B CB  1 
ATOM 3894 C CG  . LEU B 1 323 ? 135.213 156.700 151.628 1.00 0.60  ? 323 LEU B CG  1 
ATOM 3895 C CD1 . LEU B 1 323 ? 133.749 156.518 151.259 1.00 2.81  ? 323 LEU B CD1 1 
ATOM 3896 C CD2 . LEU B 1 323 ? 135.444 158.067 152.256 1.00 0.00  ? 323 LEU B CD2 1 
ATOM 3897 N N   . GLY B 1 324 ? 137.784 153.606 154.036 1.00 0.00  ? 324 GLY B N   1 
ATOM 3898 C CA  . GLY B 1 324 ? 138.111 152.653 155.079 1.00 0.26  ? 324 GLY B CA  1 
ATOM 3899 C C   . GLY B 1 324 ? 139.209 153.156 155.993 1.00 0.00  ? 324 GLY B C   1 
ATOM 3900 O O   . GLY B 1 324 ? 139.176 152.923 157.200 1.00 0.00  ? 324 GLY B O   1 
ATOM 3901 N N   . ILE B 1 325 ? 140.191 153.863 155.428 1.00 2.32  ? 325 ILE B N   1 
ATOM 3902 C CA  . ILE B 1 325 ? 141.240 154.468 156.245 1.00 1.10  ? 325 ILE B CA  1 
ATOM 3903 C C   . ILE B 1 325 ? 140.645 155.503 157.189 1.00 0.00  ? 325 ILE B C   1 
ATOM 3904 O O   . ILE B 1 325 ? 140.977 155.548 158.379 1.00 1.71  ? 325 ILE B O   1 
ATOM 3905 C CB  . ILE B 1 325 ? 142.329 155.088 155.351 1.00 2.53  ? 325 ILE B CB  1 
ATOM 3906 C CG1 . ILE B 1 325 ? 143.211 153.999 154.744 1.00 0.70  ? 325 ILE B CG1 1 
ATOM 3907 C CG2 . ILE B 1 325 ? 143.171 156.081 156.140 1.00 0.00  ? 325 ILE B CG2 1 
ATOM 3908 C CD1 . ILE B 1 325 ? 144.122 154.510 153.660 1.00 3.39  ? 325 ILE B CD1 1 
ATOM 3909 N N   . LEU B 1 326 ? 139.764 156.360 156.668 1.00 0.00  ? 326 LEU B N   1 
ATOM 3910 C CA  . LEU B 1 326 ? 139.147 157.373 157.523 1.00 0.02  ? 326 LEU B CA  1 
ATOM 3911 C C   . LEU B 1 326 ? 138.287 156.736 158.610 1.00 2.30  ? 326 LEU B C   1 
ATOM 3912 O O   . LEU B 1 326 ? 138.301 157.179 159.764 1.00 0.60  ? 326 LEU B O   1 
ATOM 3913 C CB  . LEU B 1 326 ? 138.328 158.349 156.682 1.00 1.14  ? 326 LEU B CB  1 
ATOM 3914 C CG  . LEU B 1 326 ? 139.142 159.425 155.962 1.00 3.75  ? 326 LEU B CG  1 
ATOM 3915 C CD1 . LEU B 1 326 ? 138.237 160.542 155.487 1.00 3.21  ? 326 LEU B CD1 1 
ATOM 3916 C CD2 . LEU B 1 326 ? 140.243 159.973 156.859 1.00 1.86  ? 326 LEU B CD2 1 
ATOM 3917 N N   . TRP B 1 327 ? 137.538 155.689 158.258 1.00 3.46  ? 327 TRP B N   1 
ATOM 3918 C CA  . TRP B 1 327 ? 136.726 154.969 159.234 1.00 0.00  ? 327 TRP B CA  1 
ATOM 3919 C C   . TRP B 1 327 ? 137.596 154.326 160.310 1.00 0.00  ? 327 TRP B C   1 
ATOM 3920 O O   . TRP B 1 327 ? 137.280 154.400 161.505 1.00 0.00  ? 327 TRP B O   1 
ATOM 3921 C CB  . TRP B 1 327 ? 135.885 153.923 158.500 1.00 0.00  ? 327 TRP B CB  1 
ATOM 3922 C CG  . TRP B 1 327 ? 134.959 153.101 159.339 1.00 0.00  ? 327 TRP B CG  1 
ATOM 3923 C CD1 . TRP B 1 327 ? 133.673 153.403 159.682 1.00 0.00  ? 327 TRP B CD1 1 
ATOM 3924 C CD2 . TRP B 1 327 ? 135.231 151.813 159.903 1.00 1.48  ? 327 TRP B CD2 1 
ATOM 3925 N NE1 . TRP B 1 327 ? 133.135 152.393 160.440 1.00 0.00  ? 327 TRP B NE1 1 
ATOM 3926 C CE2 . TRP B 1 327 ? 134.070 151.403 160.588 1.00 0.08  ? 327 TRP B CE2 1 
ATOM 3927 C CE3 . TRP B 1 327 ? 136.347 150.969 159.900 1.00 0.00  ? 327 TRP B CE3 1 
ATOM 3928 C CZ2 . TRP B 1 327 ? 133.992 150.188 161.267 1.00 0.00  ? 327 TRP B CZ2 1 
ATOM 3929 C CZ3 . TRP B 1 327 ? 136.268 149.763 160.576 1.00 0.00  ? 327 TRP B CZ3 1 
ATOM 3930 C CH2 . TRP B 1 327 ? 135.099 149.384 161.249 1.00 0.00  ? 327 TRP B CH2 1 
ATOM 3931 N N   . CYS B 1 328 ? 138.704 153.704 159.901 1.00 1.11  ? 328 CYS B N   1 
ATOM 3932 C CA  . CYS B 1 328 ? 139.621 153.088 160.854 1.00 0.57  ? 328 CYS B CA  1 
ATOM 3933 C C   . CYS B 1 328 ? 140.233 154.126 161.781 1.00 0.91  ? 328 CYS B C   1 
ATOM 3934 O O   . CYS B 1 328 ? 140.349 153.893 162.985 1.00 0.00  ? 328 CYS B O   1 
ATOM 3935 C CB  . CYS B 1 328 ? 140.720 152.328 160.112 1.00 2.46  ? 328 CYS B CB  1 
ATOM 3936 S SG  . CYS B 1 328 ? 140.303 150.630 159.665 1.00 8.84  ? 328 CYS B SG  1 
ATOM 3937 N N   . LEU B 1 329 ? 140.636 155.277 161.238 1.00 2.99  ? 329 LEU B N   1 
ATOM 3938 C CA  . LEU B 1 329 ? 141.215 156.326 162.072 1.00 0.79  ? 329 LEU B CA  1 
ATOM 3939 C C   . LEU B 1 329 ? 140.192 156.886 163.052 1.00 0.00  ? 329 LEU B C   1 
ATOM 3940 O O   . LEU B 1 329 ? 140.519 157.148 164.215 1.00 0.00  ? 329 LEU B O   1 
ATOM 3941 C CB  . LEU B 1 329 ? 141.787 157.442 161.199 1.00 4.30  ? 329 LEU B CB  1 
ATOM 3942 C CG  . LEU B 1 329 ? 143.070 157.110 160.436 1.00 2.94  ? 329 LEU B CG  1 
ATOM 3943 C CD1 . LEU B 1 329 ? 143.488 158.280 159.563 1.00 0.56  ? 329 LEU B CD1 1 
ATOM 3944 C CD2 . LEU B 1 329 ? 144.186 156.720 161.398 1.00 2.75  ? 329 LEU B CD2 1 
ATOM 3945 N N   . SER B 1 330 ? 138.950 157.081 162.600 1.00 0.80  ? 330 SER B N   1 
ATOM 3946 C CA  . SER B 1 330 ? 137.909 157.575 163.493 1.00 1.08  ? 330 SER B CA  1 
ATOM 3947 C C   . SER B 1 330 ? 137.641 156.588 164.623 1.00 3.48  ? 330 SER B C   1 
ATOM 3948 O O   . SER B 1 330 ? 137.529 156.982 165.792 1.00 1.82  ? 330 SER B O   1 
ATOM 3949 C CB  . SER B 1 330 ? 136.633 157.854 162.698 1.00 2.91  ? 330 SER B CB  1 
ATOM 3950 O OG  . SER B 1 330 ? 135.552 158.184 163.549 1.00 7.31  ? 330 SER B OG  1 
ATOM 3951 N N   . LEU B 1 331 ? 137.563 155.294 164.299 1.00 0.60  ? 331 LEU B N   1 
ATOM 3952 C CA  . LEU B 1 331 ? 137.362 154.289 165.338 1.00 0.61  ? 331 LEU B CA  1 
ATOM 3953 C C   . LEU B 1 331 ? 138.566 154.199 166.271 1.00 2.35  ? 331 LEU B C   1 
ATOM 3954 O O   . LEU B 1 331 ? 138.405 154.019 167.483 1.00 6.19  ? 331 LEU B O   1 
ATOM 3955 C CB  . LEU B 1 331 ? 137.070 152.930 164.708 1.00 3.70  ? 331 LEU B CB  1 
ATOM 3956 C CG  . LEU B 1 331 ? 135.651 152.410 164.927 1.00 2.67  ? 331 LEU B CG  1 
ATOM 3957 C CD1 . LEU B 1 331 ? 135.493 151.022 164.340 1.00 0.32  ? 331 LEU B CD1 1 
ATOM 3958 C CD2 . LEU B 1 331 ? 135.313 152.414 166.402 1.00 1.53  ? 331 LEU B CD2 1 
ATOM 3959 N N   . LEU B 1 332 ? 139.779 154.314 165.725 1.00 3.54  ? 332 LEU B N   1 
ATOM 3960 C CA  . LEU B 1 332 ? 140.978 154.248 166.552 1.00 2.47  ? 332 LEU B CA  1 
ATOM 3961 C C   . LEU B 1 332 ? 141.037 155.415 167.524 1.00 3.07  ? 332 LEU B C   1 
ATOM 3962 O O   . LEU B 1 332 ? 141.434 155.246 168.680 1.00 5.99  ? 332 LEU B O   1 
ATOM 3963 C CB  . LEU B 1 332 ? 142.229 154.219 165.672 1.00 3.89  ? 332 LEU B CB  1 
ATOM 3964 C CG  . LEU B 1 332 ? 142.587 152.877 165.029 1.00 4.77  ? 332 LEU B CG  1 
ATOM 3965 C CD1 . LEU B 1 332 ? 143.434 153.088 163.783 1.00 2.34  ? 332 LEU B CD1 1 
ATOM 3966 C CD2 . LEU B 1 332 ? 143.294 151.962 166.014 1.00 3.20  ? 332 LEU B CD2 1 
ATOM 3967 N N   . ALA B 1 333 ? 140.656 156.610 167.074 1.00 6.07  ? 333 ALA B N   1 
ATOM 3968 C CA  . ALA B 1 333 ? 140.579 157.744 167.989 1.00 2.65  ? 333 ALA B CA  1 
ATOM 3969 C C   . ALA B 1 333 ? 139.504 157.520 169.045 1.00 2.12  ? 333 ALA B C   1 
ATOM 3970 O O   . ALA B 1 333 ? 139.736 157.743 170.240 1.00 9.13  ? 333 ALA B O   1 
ATOM 3971 C CB  . ALA B 1 333 ? 140.319 159.030 167.210 1.00 1.76  ? 333 ALA B CB  1 
ATOM 3972 N N   . CYS B 1 334 ? 138.324 157.054 168.625 1.00 6.57  ? 334 CYS B N   1 
ATOM 3973 C CA  . CYS B 1 334 ? 137.250 156.761 169.567 1.00 5.96  ? 334 CYS B CA  1 
ATOM 3974 C C   . CYS B 1 334 ? 137.661 155.736 170.615 1.00 6.59  ? 334 CYS B C   1 
ATOM 3975 O O   . CYS B 1 334 ? 137.147 155.776 171.738 1.00 9.48  ? 334 CYS B O   1 
ATOM 3976 C CB  . CYS B 1 334 ? 136.018 156.265 168.804 1.00 3.65  ? 334 CYS B CB  1 
ATOM 3977 S SG  . CYS B 1 334 ? 134.440 156.563 169.620 1.00 24.48 ? 334 CYS B SG  1 
ATOM 3978 N N   . PHE B 1 335 ? 138.572 154.829 170.275 1.00 8.90  ? 335 PHE B N   1 
ATOM 3979 C CA  . PHE B 1 335 ? 139.060 153.825 171.205 1.00 4.09  ? 335 PHE B CA  1 
ATOM 3980 C C   . PHE B 1 335 ? 140.244 154.286 172.044 1.00 8.29  ? 335 PHE B C   1 
ATOM 3981 O O   . PHE B 1 335 ? 140.368 153.851 173.194 1.00 10.02 ? 335 PHE B O   1 
ATOM 3982 C CB  . PHE B 1 335 ? 139.458 152.552 170.443 1.00 4.80  ? 335 PHE B CB  1 
ATOM 3983 C CG  . PHE B 1 335 ? 138.288 151.736 169.980 1.00 3.35  ? 335 PHE B CG  1 
ATOM 3984 C CD1 . PHE B 1 335 ? 137.057 151.852 170.603 1.00 7.53  ? 335 PHE B CD1 1 
ATOM 3985 C CD2 . PHE B 1 335 ? 138.413 150.865 168.913 1.00 5.11  ? 335 PHE B CD2 1 
ATOM 3986 C CE1 . PHE B 1 335 ? 135.978 151.104 170.177 1.00 8.73  ? 335 PHE B CE1 1 
ATOM 3987 C CE2 . PHE B 1 335 ? 137.338 150.116 168.483 1.00 6.54  ? 335 PHE B CE2 1 
ATOM 3988 C CZ  . PHE B 1 335 ? 136.119 150.236 169.115 1.00 5.31  ? 335 PHE B CZ  1 
ATOM 3989 N N   . PHE B 1 336 ? 141.111 155.144 171.510 1.00 8.84  ? 336 PHE B N   1 
ATOM 3990 C CA  . PHE B 1 336 ? 142.344 155.541 172.174 1.00 7.15  ? 336 PHE B CA  1 
ATOM 3991 C C   . PHE B 1 336 ? 142.228 156.858 172.926 1.00 7.56  ? 336 PHE B C   1 
ATOM 3992 O O   . PHE B 1 336 ? 143.200 157.266 173.569 1.00 5.54  ? 336 PHE B O   1 
ATOM 3993 C CB  . PHE B 1 336 ? 143.479 155.638 171.149 1.00 4.48  ? 336 PHE B CB  1 
ATOM 3994 C CG  . PHE B 1 336 ? 143.964 154.307 170.656 1.00 7.88  ? 336 PHE B CG  1 
ATOM 3995 C CD1 . PHE B 1 336 ? 143.790 153.165 171.418 1.00 8.24  ? 336 PHE B CD1 1 
ATOM 3996 C CD2 . PHE B 1 336 ? 144.588 154.196 169.425 1.00 7.66  ? 336 PHE B CD2 1 
ATOM 3997 C CE1 . PHE B 1 336 ? 144.233 151.938 170.966 1.00 6.77  ? 336 PHE B CE1 1 
ATOM 3998 C CE2 . PHE B 1 336 ? 145.035 152.970 168.967 1.00 8.25  ? 336 PHE B CE2 1 
ATOM 3999 C CZ  . PHE B 1 336 ? 144.857 151.841 169.738 1.00 5.47  ? 336 PHE B CZ  1 
ATOM 4000 N N   . ALA B 1 337 ? 141.071 157.528 172.864 1.00 9.11  ? 337 ALA B N   1 
ATOM 4001 C CA  . ALA B 1 337 ? 140.842 158.753 173.627 1.00 6.99  ? 337 ALA B CA  1 
ATOM 4002 C C   . ALA B 1 337 ? 141.921 159.795 173.348 1.00 8.19  ? 337 ALA B C   1 
ATOM 4003 O O   . ALA B 1 337 ? 142.783 160.046 174.199 1.00 10.83 ? 337 ALA B O   1 
ATOM 4004 C CB  . ALA B 1 337 ? 140.772 158.450 175.125 1.00 5.35  ? 337 ALA B CB  1 
ATOM 4005 N N   . PRO B 1 338 ? 141.903 160.417 172.173 1.00 7.14  ? 338 PRO B N   1 
ATOM 4006 C CA  . PRO B 1 338 ? 142.924 161.416 171.838 1.00 9.55  ? 338 PRO B CA  1 
ATOM 4007 C C   . PRO B 1 338 ? 142.710 162.727 172.580 1.00 12.60 ? 338 PRO B C   1 
ATOM 4008 O O   . PRO B 1 338 ? 141.888 162.788 173.501 1.00 14.83 ? 338 PRO B O   1 
ATOM 4009 C CB  . PRO B 1 338 ? 142.769 161.575 170.321 1.00 8.94  ? 338 PRO B CB  1 
ATOM 4010 C CG  . PRO B 1 338 ? 141.340 161.222 170.046 1.00 7.26  ? 338 PRO B CG  1 
ATOM 4011 C CD  . PRO B 1 338 ? 140.805 160.403 171.193 1.00 9.66  ? 338 PRO B CD  1 
ATOM 4012 N N   . ILE B 1 339 ? 143.462 163.763 172.196 1.00 11.23 ? 339 ILE B N   1 
ATOM 4013 C CA  . ILE B 1 339 ? 143.556 165.038 172.909 1.00 6.97  ? 339 ILE B CA  1 
ATOM 4014 C C   . ILE B 1 339 ? 142.202 165.506 173.438 1.00 8.87  ? 339 ILE B C   1 
ATOM 4015 O O   . ILE B 1 339 ? 141.198 165.516 172.716 1.00 7.00  ? 339 ILE B O   1 
ATOM 4016 C CB  . ILE B 1 339 ? 144.223 166.097 172.006 1.00 8.89  ? 339 ILE B CB  1 
ATOM 4017 C CG1 . ILE B 1 339 ? 143.404 166.354 170.741 1.00 6.32  ? 339 ILE B CG1 1 
ATOM 4018 C CG2 . ILE B 1 339 ? 145.634 165.669 171.634 1.00 10.12 ? 339 ILE B CG2 1 
ATOM 4019 C CD1 . ILE B 1 339 ? 143.138 167.811 170.478 1.00 9.24  ? 339 ILE B CD1 1 
ATOM 4020 N N   . SER B 1 340 ? 142.174 165.871 174.724 1.00 13.17 ? 340 SER B N   1 
ATOM 4021 C CA  . SER B 1 340 ? 140.920 165.909 175.472 1.00 8.04  ? 340 SER B CA  1 
ATOM 4022 C C   . SER B 1 340 ? 140.069 167.122 175.123 1.00 9.95  ? 340 SER B C   1 
ATOM 4023 O O   . SER B 1 340 ? 138.885 167.175 175.474 1.00 14.46 ? 340 SER B O   1 
ATOM 4024 C CB  . SER B 1 340 ? 141.207 165.881 176.974 1.00 9.87  ? 340 SER B CB  1 
ATOM 4025 O OG  . SER B 1 340 ? 141.855 167.069 177.394 1.00 14.17 ? 340 SER B OG  1 
ATOM 4026 N N   . VAL B 1 341 ? 140.651 168.111 174.450 1.00 7.79  ? 341 VAL B N   1 
ATOM 4027 C CA  . VAL B 1 341 ? 139.913 169.322 174.104 1.00 8.23  ? 341 VAL B CA  1 
ATOM 4028 C C   . VAL B 1 341 ? 138.742 168.979 173.188 1.00 10.62 ? 341 VAL B C   1 
ATOM 4029 O O   . VAL B 1 341 ? 137.681 169.609 173.262 1.00 13.32 ? 341 VAL B O   1 
ATOM 4030 C CB  . VAL B 1 341 ? 140.832 170.381 173.469 1.00 8.56  ? 341 VAL B CB  1 
ATOM 4031 C CG1 . VAL B 1 341 ? 140.010 171.578 173.009 1.00 7.53  ? 341 VAL B CG1 1 
ATOM 4032 C CG2 . VAL B 1 341 ? 141.890 170.831 174.459 1.00 9.50  ? 341 VAL B CG2 1 
ATOM 4033 N N   . ILE B 1 342 ? 138.921 167.992 172.316 1.00 7.25  ? 342 ILE B N   1 
ATOM 4034 C CA  . ILE B 1 342 ? 137.837 167.540 171.446 1.00 5.86  ? 342 ILE B CA  1 
ATOM 4035 C C   . ILE B 1 342 ? 137.243 166.259 172.023 1.00 8.09  ? 342 ILE B C   1 
ATOM 4036 O O   . ILE B 1 342 ? 137.947 165.243 172.128 1.00 12.14 ? 342 ILE B O   1 
ATOM 4037 C CB  . ILE B 1 342 ? 138.324 167.341 170.002 1.00 7.07  ? 342 ILE B CB  1 
ATOM 4038 C CG1 . ILE B 1 342 ? 137.371 166.431 169.230 1.00 10.92 ? 342 ILE B CG1 1 
ATOM 4039 C CG2 . ILE B 1 342 ? 139.725 166.772 169.981 1.00 7.44  ? 342 ILE B CG2 1 
ATOM 4040 C CD1 . ILE B 1 342 ? 137.721 166.292 167.774 1.00 8.64  ? 342 ILE B CD1 1 
ATOM 4041 N N   . PRO B 1 343 ? 135.981 166.269 172.449 1.00 6.82  ? 343 PRO B N   1 
ATOM 4042 C CA  . PRO B 1 343 ? 135.353 165.039 172.941 1.00 6.13  ? 343 PRO B CA  1 
ATOM 4043 C C   . PRO B 1 343 ? 135.336 163.940 171.888 1.00 9.41  ? 343 PRO B C   1 
ATOM 4044 O O   . PRO B 1 343 ? 135.489 164.178 170.688 1.00 10.60 ? 343 PRO B O   1 
ATOM 4045 C CB  . PRO B 1 343 ? 133.925 165.489 173.282 1.00 6.85  ? 343 PRO B CB  1 
ATOM 4046 C CG  . PRO B 1 343 ? 133.901 167.008 173.003 1.00 6.33  ? 343 PRO B CG  1 
ATOM 4047 C CD  . PRO B 1 343 ? 135.322 167.428 173.057 1.00 4.21  ? 343 PRO B CD  1 
ATOM 4048 N N   . THR B 1 344 ? 135.136 162.710 172.366 1.00 4.39  ? 344 THR B N   1 
ATOM 4049 C CA  . THR B 1 344 ? 135.113 161.549 171.483 1.00 6.99  ? 344 THR B CA  1 
ATOM 4050 C C   . THR B 1 344 ? 133.851 161.473 170.633 1.00 7.99  ? 344 THR B C   1 
ATOM 4051 O O   . THR B 1 344 ? 133.818 160.687 169.681 1.00 11.08 ? 344 THR B O   1 
ATOM 4052 C CB  . THR B 1 344 ? 135.251 160.258 172.293 1.00 6.32  ? 344 THR B CB  1 
ATOM 4053 O OG1 . THR B 1 344 ? 134.191 160.176 173.254 1.00 5.98  ? 344 THR B OG1 1 
ATOM 4054 C CG2 . THR B 1 344 ? 136.591 160.216 173.013 1.00 6.98  ? 344 THR B CG2 1 
ATOM 4055 N N   . TYR B 1 345 ? 132.825 162.263 170.944 1.00 9.41  ? 345 TYR B N   1 
ATOM 4056 C CA  . TYR B 1 345 ? 131.569 162.245 170.208 1.00 7.82  ? 345 TYR B CA  1 
ATOM 4057 C C   . TYR B 1 345 ? 131.608 163.104 168.947 1.00 7.75  ? 345 TYR B C   1 
ATOM 4058 O O   . TYR B 1 345 ? 130.552 163.398 168.375 1.00 14.63 ? 345 TYR B O   1 
ATOM 4059 C CB  . TYR B 1 345 ? 130.416 162.660 171.135 1.00 8.47  ? 345 TYR B CB  1 
ATOM 4060 C CG  . TYR B 1 345 ? 130.438 164.084 171.689 1.00 6.41  ? 345 TYR B CG  1 
ATOM 4061 C CD1 . TYR B 1 345 ? 130.573 165.193 170.862 1.00 8.75  ? 345 TYR B CD1 1 
ATOM 4062 C CD2 . TYR B 1 345 ? 130.313 164.308 173.054 1.00 8.39  ? 345 TYR B CD2 1 
ATOM 4063 C CE1 . TYR B 1 345 ? 130.588 166.473 171.374 1.00 7.91  ? 345 TYR B CE1 1 
ATOM 4064 C CE2 . TYR B 1 345 ? 130.325 165.588 173.576 1.00 8.36  ? 345 TYR B CE2 1 
ATOM 4065 C CZ  . TYR B 1 345 ? 130.463 166.666 172.731 1.00 9.81  ? 345 TYR B CZ  1 
ATOM 4066 O OH  . TYR B 1 345 ? 130.477 167.942 173.245 1.00 13.02 ? 345 TYR B OH  1 
ATOM 4067 N N   . VAL B 1 346 ? 132.796 163.500 168.500 1.00 9.26  ? 346 VAL B N   1 
ATOM 4068 C CA  . VAL B 1 346 ? 132.939 164.372 167.340 1.00 4.73  ? 346 VAL B CA  1 
ATOM 4069 C C   . VAL B 1 346 ? 133.570 163.579 166.203 1.00 3.93  ? 346 VAL B C   1 
ATOM 4070 O O   . VAL B 1 346 ? 133.316 163.850 165.024 1.00 8.24  ? 346 VAL B O   1 
ATOM 4071 C CB  . VAL B 1 346 ? 133.770 165.622 167.697 1.00 5.46  ? 346 VAL B CB  1 
ATOM 4072 C CG1 . VAL B 1 346 ? 134.287 166.325 166.449 1.00 4.07  ? 346 VAL B CG1 1 
ATOM 4073 C CG2 . VAL B 1 346 ? 132.947 166.577 168.545 1.00 6.79  ? 346 VAL B CG2 1 
ATOM 4074 N N   . TYR B 1 347 ? 134.376 162.578 166.548 1.00 4.86  ? 347 TYR B N   1 
ATOM 4075 C CA  . TYR B 1 347 ? 135.102 161.808 165.542 1.00 4.92  ? 347 TYR B CA  1 
ATOM 4076 C C   . TYR B 1 347 ? 134.171 161.048 164.598 1.00 3.52  ? 347 TYR B C   1 
ATOM 4077 O O   . TYR B 1 347 ? 134.386 161.097 163.381 1.00 6.67  ? 347 TYR B O   1 
ATOM 4078 C CB  . TYR B 1 347 ? 136.111 160.869 166.212 1.00 3.29  ? 347 TYR B CB  1 
ATOM 4079 C CG  . TYR B 1 347 ? 137.219 161.626 166.903 1.00 5.53  ? 347 TYR B CG  1 
ATOM 4080 C CD1 . TYR B 1 347 ? 137.020 162.214 168.144 1.00 8.94  ? 347 TYR B CD1 1 
ATOM 4081 C CD2 . TYR B 1 347 ? 138.446 161.810 166.282 1.00 8.04  ? 347 TYR B CD2 1 
ATOM 4082 C CE1 . TYR B 1 347 ? 138.025 162.924 168.767 1.00 8.98  ? 347 TYR B CE1 1 
ATOM 4083 C CE2 . TYR B 1 347 ? 139.455 162.521 166.895 1.00 6.27  ? 347 TYR B CE2 1 
ATOM 4084 C CZ  . TYR B 1 347 ? 139.239 163.077 168.136 1.00 5.25  ? 347 TYR B CZ  1 
ATOM 4085 O OH  . TYR B 1 347 ? 140.242 163.789 168.750 1.00 10.15 ? 347 TYR B OH  1 
ATOM 4086 N N   . PRO B 1 348 ? 133.145 160.329 165.081 1.00 5.98  ? 348 PRO B N   1 
ATOM 4087 C CA  . PRO B 1 348 ? 132.137 159.826 164.128 1.00 3.28  ? 348 PRO B CA  1 
ATOM 4088 C C   . PRO B 1 348 ? 131.431 160.950 163.392 1.00 6.56  ? 348 PRO B C   1 
ATOM 4089 O O   . PRO B 1 348 ? 131.149 160.835 162.190 1.00 10.11 ? 348 PRO B O   1 
ATOM 4090 C CB  . PRO B 1 348 ? 131.166 159.027 165.011 1.00 4.94  ? 348 PRO B CB  1 
ATOM 4091 C CG  . PRO B 1 348 ? 131.480 159.394 166.408 1.00 0.93  ? 348 PRO B CG  1 
ATOM 4092 C CD  . PRO B 1 348 ? 132.891 159.856 166.453 1.00 6.75  ? 348 PRO B CD  1 
ATOM 4093 N N   . LEU B 1 349 ? 131.155 162.052 164.095 1.00 5.58  ? 349 LEU B N   1 
ATOM 4094 C CA  . LEU B 1 349 ? 130.543 163.210 163.455 1.00 3.02  ? 349 LEU B CA  1 
ATOM 4095 C C   . LEU B 1 349 ? 131.456 163.786 162.385 1.00 4.89  ? 349 LEU B C   1 
ATOM 4096 O O   . LEU B 1 349 ? 130.998 164.123 161.290 1.00 7.36  ? 349 LEU B O   1 
ATOM 4097 C CB  . LEU B 1 349 ? 130.206 164.270 164.504 1.00 3.39  ? 349 LEU B CB  1 
ATOM 4098 C CG  . LEU B 1 349 ? 129.108 165.283 164.175 1.00 5.15  ? 349 LEU B CG  1 
ATOM 4099 C CD1 . LEU B 1 349 ? 128.085 164.692 163.217 1.00 5.93  ? 349 LEU B CD1 1 
ATOM 4100 C CD2 . LEU B 1 349 ? 128.436 165.763 165.454 1.00 4.54  ? 349 LEU B CD2 1 
ATOM 4101 N N   . ALA B 1 350 ? 132.753 163.897 162.679 1.00 0.52  ? 350 ALA B N   1 
ATOM 4102 C CA  . ALA B 1 350 ? 133.696 164.397 161.684 1.00 0.70  ? 350 ALA B CA  1 
ATOM 4103 C C   . ALA B 1 350 ? 133.791 163.455 160.491 1.00 2.35  ? 350 ALA B C   1 
ATOM 4104 O O   . ALA B 1 350 ? 133.848 163.904 159.342 1.00 1.95  ? 350 ALA B O   1 
ATOM 4105 C CB  . ALA B 1 350 ? 135.070 164.604 162.319 1.00 2.78  ? 350 ALA B CB  1 
ATOM 4106 N N   . LEU B 1 351 ? 133.803 162.144 160.744 1.00 3.27  ? 351 LEU B N   1 
ATOM 4107 C CA  . LEU B 1 351 ? 133.868 161.174 159.655 1.00 3.72  ? 351 LEU B CA  1 
ATOM 4108 C C   . LEU B 1 351 ? 132.669 161.308 158.723 1.00 1.38  ? 351 LEU B C   1 
ATOM 4109 O O   . LEU B 1 351 ? 132.824 161.408 157.499 1.00 0.00  ? 351 LEU B O   1 
ATOM 4110 C CB  . LEU B 1 351 ? 133.952 159.758 160.223 1.00 5.49  ? 351 LEU B CB  1 
ATOM 4111 C CG  . LEU B 1 351 ? 133.625 158.620 159.254 1.00 2.28  ? 351 LEU B CG  1 
ATOM 4112 C CD1 . LEU B 1 351 ? 134.790 158.359 158.312 1.00 0.71  ? 351 LEU B CD1 1 
ATOM 4113 C CD2 . LEU B 1 351 ? 133.245 157.355 160.009 1.00 0.40  ? 351 LEU B CD2 1 
ATOM 4114 N N   . TYR B 1 352 ? 131.460 161.332 159.288 1.00 0.63  ? 352 TYR B N   1 
ATOM 4115 C CA  . TYR B 1 352 ? 130.275 161.406 158.440 1.00 1.17  ? 352 TYR B CA  1 
ATOM 4116 C C   . TYR B 1 352 ? 130.121 162.781 157.800 1.00 3.13  ? 352 TYR B C   1 
ATOM 4117 O O   . TYR B 1 352 ? 129.637 162.881 156.666 1.00 2.95  ? 352 TYR B O   1 
ATOM 4118 C CB  . TYR B 1 352 ? 129.032 161.020 159.239 1.00 0.85  ? 352 TYR B CB  1 
ATOM 4119 C CG  . TYR B 1 352 ? 129.011 159.552 159.601 1.00 2.30  ? 352 TYR B CG  1 
ATOM 4120 C CD1 . TYR B 1 352 ? 129.194 158.579 158.628 1.00 1.29  ? 352 TYR B CD1 1 
ATOM 4121 C CD2 . TYR B 1 352 ? 128.829 159.138 160.915 1.00 2.06  ? 352 TYR B CD2 1 
ATOM 4122 C CE1 . TYR B 1 352 ? 129.186 157.236 158.949 1.00 3.58  ? 352 TYR B CE1 1 
ATOM 4123 C CE2 . TYR B 1 352 ? 128.819 157.797 161.245 1.00 0.78  ? 352 TYR B CE2 1 
ATOM 4124 C CZ  . TYR B 1 352 ? 128.997 156.850 160.257 1.00 4.12  ? 352 TYR B CZ  1 
ATOM 4125 O OH  . TYR B 1 352 ? 128.988 155.511 160.576 1.00 4.43  ? 352 TYR B OH  1 
ATOM 4126 N N   . GLY B 1 353 ? 130.548 163.844 158.485 1.00 1.27  ? 353 GLY B N   1 
ATOM 4127 C CA  . GLY B 1 353 ? 130.523 165.159 157.873 1.00 1.48  ? 353 GLY B CA  1 
ATOM 4128 C C   . GLY B 1 353 ? 131.464 165.264 156.691 1.00 2.04  ? 353 GLY B C   1 
ATOM 4129 O O   . GLY B 1 353 ? 131.111 165.830 155.655 1.00 7.90  ? 353 GLY B O   1 
ATOM 4130 N N   . PHE B 1 354 ? 132.673 164.714 156.825 1.00 3.40  ? 354 PHE B N   1 
ATOM 4131 C CA  . PHE B 1 354 ? 133.591 164.696 155.695 1.00 0.91  ? 354 PHE B CA  1 
ATOM 4132 C C   . PHE B 1 354 ? 133.048 163.834 154.567 1.00 1.95  ? 354 PHE B C   1 
ATOM 4133 O O   . PHE B 1 354 ? 133.236 164.155 153.393 1.00 2.57  ? 354 PHE B O   1 
ATOM 4134 C CB  . PHE B 1 354 ? 134.972 164.201 156.118 1.00 3.31  ? 354 PHE B CB  1 
ATOM 4135 C CG  . PHE B 1 354 ? 135.958 164.148 154.986 1.00 4.39  ? 354 PHE B CG  1 
ATOM 4136 C CD1 . PHE B 1 354 ? 136.694 165.268 154.640 1.00 0.42  ? 354 PHE B CD1 1 
ATOM 4137 C CD2 . PHE B 1 354 ? 136.133 162.986 154.252 1.00 3.83  ? 354 PHE B CD2 1 
ATOM 4138 C CE1 . PHE B 1 354 ? 137.594 165.227 153.594 1.00 4.23  ? 354 PHE B CE1 1 
ATOM 4139 C CE2 . PHE B 1 354 ? 137.032 162.940 153.202 1.00 4.53  ? 354 PHE B CE2 1 
ATOM 4140 C CZ  . PHE B 1 354 ? 137.763 164.061 152.875 1.00 3.98  ? 354 PHE B CZ  1 
ATOM 4141 N N   . MET B 1 355 ? 132.388 162.726 154.902 1.00 6.35  ? 355 MET B N   1 
ATOM 4142 C CA  . MET B 1 355 ? 131.794 161.883 153.869 1.00 1.86  ? 355 MET B CA  1 
ATOM 4143 C C   . MET B 1 355 ? 130.727 162.647 153.088 1.00 2.73  ? 355 MET B C   1 
ATOM 4144 O O   . MET B 1 355 ? 130.710 162.635 151.849 1.00 1.91  ? 355 MET B O   1 
ATOM 4145 C CB  . MET B 1 355 ? 131.220 160.627 154.521 1.00 6.11  ? 355 MET B CB  1 
ATOM 4146 C CG  . MET B 1 355 ? 132.121 159.411 154.404 1.00 4.94  ? 355 MET B CG  1 
ATOM 4147 S SD  . MET B 1 355 ? 131.695 158.121 155.589 1.00 11.23 ? 355 MET B SD  1 
ATOM 4148 C CE  . MET B 1 355 ? 130.316 157.343 154.770 1.00 6.93  ? 355 MET B CE  1 
ATOM 4149 N N   . VAL B 1 356 ? 129.855 163.361 153.805 1.00 5.12  ? 356 VAL B N   1 
ATOM 4150 C CA  . VAL B 1 356 ? 128.812 164.154 153.158 1.00 6.33  ? 356 VAL B CA  1 
ATOM 4151 C C   . VAL B 1 356 ? 129.425 165.263 152.309 1.00 4.34  ? 356 VAL B C   1 
ATOM 4152 O O   . VAL B 1 356 ? 129.005 165.496 151.169 1.00 4.17  ? 356 VAL B O   1 
ATOM 4153 C CB  . VAL B 1 356 ? 127.842 164.718 154.215 1.00 1.84  ? 356 VAL B CB  1 
ATOM 4154 C CG1 . VAL B 1 356 ? 127.111 165.941 153.681 1.00 5.09  ? 356 VAL B CG1 1 
ATOM 4155 C CG2 . VAL B 1 356 ? 126.854 163.649 154.655 1.00 0.39  ? 356 VAL B CG2 1 
ATOM 4156 N N   . PHE B 1 357 ? 130.426 165.965 152.847 1.00 4.43  ? 357 PHE B N   1 
ATOM 4157 C CA  . PHE B 1 357 ? 131.038 167.068 152.113 1.00 4.86  ? 357 PHE B CA  1 
ATOM 4158 C C   . PHE B 1 357 ? 131.785 166.572 150.881 1.00 4.67  ? 357 PHE B C   1 
ATOM 4159 O O   . PHE B 1 357 ? 131.732 167.205 149.822 1.00 4.98  ? 357 PHE B O   1 
ATOM 4160 C CB  . PHE B 1 357 ? 131.970 167.857 153.029 1.00 3.92  ? 357 PHE B CB  1 
ATOM 4161 C CG  . PHE B 1 357 ? 131.301 169.006 153.726 1.00 5.16  ? 357 PHE B CG  1 
ATOM 4162 C CD1 . PHE B 1 357 ? 129.996 168.896 154.175 1.00 4.84  ? 357 PHE B CD1 1 
ATOM 4163 C CD2 . PHE B 1 357 ? 131.974 170.198 153.926 1.00 7.89  ? 357 PHE B CD2 1 
ATOM 4164 C CE1 . PHE B 1 357 ? 129.375 169.952 154.815 1.00 7.78  ? 357 PHE B CE1 1 
ATOM 4165 C CE2 . PHE B 1 357 ? 131.358 171.258 154.565 1.00 6.44  ? 357 PHE B CE2 1 
ATOM 4166 C CZ  . PHE B 1 357 ? 130.057 171.135 155.009 1.00 9.03  ? 357 PHE B CZ  1 
ATOM 4167 N N   . PHE B 1 358 ? 132.481 165.441 151.001 1.00 4.05  ? 358 PHE B N   1 
ATOM 4168 C CA  . PHE B 1 358 ? 133.150 164.841 149.855 1.00 3.79  ? 358 PHE B CA  1 
ATOM 4169 C C   . PHE B 1 358 ? 132.143 164.466 148.781 1.00 4.50  ? 358 PHE B C   1 
ATOM 4170 O O   . PHE B 1 358 ? 132.396 164.660 147.588 1.00 4.84  ? 358 PHE B O   1 
ATOM 4171 C CB  . PHE B 1 358 ? 133.949 163.615 150.308 1.00 2.33  ? 358 PHE B CB  1 
ATOM 4172 C CG  . PHE B 1 358 ? 134.552 162.822 149.181 1.00 4.19  ? 358 PHE B CG  1 
ATOM 4173 C CD1 . PHE B 1 358 ? 135.810 163.135 148.695 1.00 7.27  ? 358 PHE B CD1 1 
ATOM 4174 C CD2 . PHE B 1 358 ? 133.869 161.756 148.617 1.00 3.40  ? 358 PHE B CD2 1 
ATOM 4175 C CE1 . PHE B 1 358 ? 136.370 162.408 147.662 1.00 4.27  ? 358 PHE B CE1 1 
ATOM 4176 C CE2 . PHE B 1 358 ? 134.423 161.029 147.583 1.00 3.46  ? 358 PHE B CE2 1 
ATOM 4177 C CZ  . PHE B 1 358 ? 135.675 161.356 147.106 1.00 6.26  ? 358 PHE B CZ  1 
ATOM 4178 N N   . LEU B 1 359 ? 130.991 163.929 149.187 1.00 1.44  ? 359 LEU B N   1 
ATOM 4179 C CA  . LEU B 1 359 ? 129.950 163.611 148.218 1.00 3.26  ? 359 LEU B CA  1 
ATOM 4180 C C   . LEU B 1 359 ? 129.357 164.869 147.588 1.00 2.97  ? 359 LEU B C   1 
ATOM 4181 O O   . LEU B 1 359 ? 128.960 164.844 146.418 1.00 8.02  ? 359 LEU B O   1 
ATOM 4182 C CB  . LEU B 1 359 ? 128.861 162.775 148.896 1.00 3.53  ? 359 LEU B CB  1 
ATOM 4183 C CG  . LEU B 1 359 ? 127.768 162.063 148.088 1.00 6.39  ? 359 LEU B CG  1 
ATOM 4184 C CD1 . LEU B 1 359 ? 126.463 162.836 148.150 1.00 2.99  ? 359 LEU B CD1 1 
ATOM 4185 C CD2 . LEU B 1 359 ? 128.180 161.796 146.642 1.00 1.08  ? 359 LEU B CD2 1 
ATOM 4186 N N   . ILE B 1 360 ? 129.311 165.979 148.325 1.00 3.64  ? 360 ILE B N   1 
ATOM 4187 C CA  . ILE B 1 360 ? 128.490 167.125 147.941 1.00 3.64  ? 360 ILE B CA  1 
ATOM 4188 C C   . ILE B 1 360 ? 129.294 168.362 147.556 1.00 5.98  ? 360 ILE B C   1 
ATOM 4189 O O   . ILE B 1 360 ? 128.693 169.336 147.072 1.00 5.90  ? 360 ILE B O   1 
ATOM 4190 C CB  . ILE B 1 360 ? 127.483 167.484 149.056 1.00 5.93  ? 360 ILE B CB  1 
ATOM 4191 C CG1 . ILE B 1 360 ? 126.173 168.001 148.461 1.00 7.56  ? 360 ILE B CG1 1 
ATOM 4192 C CG2 . ILE B 1 360 ? 128.083 168.493 150.031 1.00 5.23  ? 360 ILE B CG2 1 
ATOM 4193 C CD1 . ILE B 1 360 ? 124.977 167.805 149.364 1.00 6.10  ? 360 ILE B CD1 1 
ATOM 4194 N N   . ASN B 1 361 ? 130.613 168.366 147.736 1.00 5.58  ? 361 ASN B N   1 
ATOM 4195 C CA  . ASN B 1 361 ? 131.377 169.594 147.538 1.00 4.18  ? 361 ASN B CA  1 
ATOM 4196 C C   . ASN B 1 361 ? 131.282 170.054 146.085 1.00 7.51  ? 361 ASN B C   1 
ATOM 4197 O O   . ASN B 1 361 ? 131.454 169.240 145.166 1.00 10.91 ? 361 ASN B O   1 
ATOM 4198 C CB  . ASN B 1 361 ? 132.842 169.408 147.934 1.00 7.04  ? 361 ASN B CB  1 
ATOM 4199 C CG  . ASN B 1 361 ? 133.552 168.379 147.085 1.00 7.74  ? 361 ASN B CG  1 
ATOM 4200 O OD1 . ASN B 1 361 ? 133.063 167.266 146.906 1.00 11.60 ? 361 ASN B OD1 1 
ATOM 4201 N ND2 . ASN B 1 361 ? 134.710 168.748 146.550 1.00 5.03  ? 361 ASN B ND2 1 
ATOM 4202 N N   . PRO B 1 362 ? 131.005 171.338 145.833 1.00 6.57  ? 362 PRO B N   1 
ATOM 4203 C CA  . PRO B 1 362 ? 130.855 171.808 144.449 1.00 5.74  ? 362 PRO B CA  1 
ATOM 4204 C C   . PRO B 1 362 ? 132.169 171.968 143.707 1.00 4.41  ? 362 PRO B C   1 
ATOM 4205 O O   . PRO B 1 362 ? 132.146 172.190 142.489 1.00 10.29 ? 362 PRO B O   1 
ATOM 4206 C CB  . PRO B 1 362 ? 130.148 173.167 144.609 1.00 5.17  ? 362 PRO B CB  1 
ATOM 4207 C CG  . PRO B 1 362 ? 130.018 173.414 146.095 1.00 5.96  ? 362 PRO B CG  1 
ATOM 4208 C CD  . PRO B 1 362 ? 130.880 172.430 146.809 1.00 5.77  ? 362 PRO B CD  1 
ATOM 4209 N N   . THR B 1 363 ? 133.303 171.866 144.395 1.00 9.58  ? 363 THR B N   1 
ATOM 4210 C CA  . THR B 1 363 ? 134.595 171.976 143.734 1.00 5.45  ? 363 THR B CA  1 
ATOM 4211 C C   . THR B 1 363 ? 134.792 170.825 142.753 1.00 6.88  ? 363 THR B C   1 
ATOM 4212 O O   . THR B 1 363 ? 134.317 169.708 142.972 1.00 11.90 ? 363 THR B O   1 
ATOM 4213 C CB  . THR B 1 363 ? 135.719 171.990 144.769 1.00 8.00  ? 363 THR B CB  1 
ATOM 4214 O OG1 . THR B 1 363 ? 135.716 170.756 145.497 1.00 10.68 ? 363 THR B OG1 1 
ATOM 4215 C CG2 . THR B 1 363 ? 135.528 173.147 145.741 1.00 5.78  ? 363 THR B CG2 1 
ATOM 4216 N N   . LYS B 1 364 ? 135.499 171.110 141.666 1.00 5.43  ? 364 LYS B N   1 
ATOM 4217 C CA  . LYS B 1 364 ? 135.673 170.163 140.567 1.00 2.51  ? 364 LYS B CA  1 
ATOM 4218 C C   . LYS B 1 364 ? 136.965 169.368 140.750 1.00 7.06  ? 364 LYS B C   1 
ATOM 4219 O O   . LYS B 1 364 ? 137.855 169.377 139.900 1.00 9.04  ? 364 LYS B O   1 
ATOM 4220 C CB  . LYS B 1 364 ? 135.676 170.914 139.239 1.00 3.78  ? 364 LYS B CB  1 
ATOM 4221 C CG  . LYS B 1 364 ? 134.303 171.321 138.734 1.00 5.51  ? 364 LYS B CG  1 
ATOM 4222 C CD  . LYS B 1 364 ? 134.230 171.270 137.219 1.00 7.44  ? 364 LYS B CD  1 
ATOM 4223 C CE  . LYS B 1 364 ? 132.789 171.271 136.742 1.00 5.69  ? 364 LYS B CE  1 
ATOM 4224 N NZ  . LYS B 1 364 ? 132.309 172.653 136.457 1.00 8.71  ? 364 LYS B NZ  1 
ATOM 4225 N N   . THR B 1 365 ? 137.065 168.660 141.877 1.00 7.57  ? 365 THR B N   1 
ATOM 4226 C CA  . THR B 1 365 ? 138.353 168.126 142.311 1.00 6.26  ? 365 THR B CA  1 
ATOM 4227 C C   . THR B 1 365 ? 138.410 166.602 142.325 1.00 7.69  ? 365 THR B C   1 
ATOM 4228 O O   . THR B 1 365 ? 139.287 166.027 141.672 1.00 10.92 ? 365 THR B O   1 
ATOM 4229 C CB  . THR B 1 365 ? 138.698 168.693 143.693 1.00 7.57  ? 365 THR B CB  1 
ATOM 4230 O OG1 . THR B 1 365 ? 138.137 170.005 143.823 1.00 10.73 ? 365 THR B OG1 1 
ATOM 4231 C CG2 . THR B 1 365 ? 140.205 168.797 143.854 1.00 9.14  ? 365 THR B CG2 1 
ATOM 4232 N N   . PHE B 1 366 ? 137.518 165.919 143.046 1.00 7.98  ? 366 PHE B N   1 
ATOM 4233 C CA  . PHE B 1 366 ? 137.632 164.476 143.261 1.00 6.06  ? 366 PHE B CA  1 
ATOM 4234 C C   . PHE B 1 366 ? 136.416 163.771 142.671 1.00 4.90  ? 366 PHE B C   1 
ATOM 4235 O O   . PHE B 1 366 ? 135.330 163.810 143.259 1.00 3.12  ? 366 PHE B O   1 
ATOM 4236 C CB  . PHE B 1 366 ? 137.766 164.147 144.750 1.00 4.55  ? 366 PHE B CB  1 
ATOM 4237 C CG  . PHE B 1 366 ? 138.970 164.759 145.408 1.00 2.91  ? 366 PHE B CG  1 
ATOM 4238 C CD1 . PHE B 1 366 ? 138.918 166.043 145.922 1.00 4.89  ? 366 PHE B CD1 1 
ATOM 4239 C CD2 . PHE B 1 366 ? 140.154 164.050 145.516 1.00 6.01  ? 366 PHE B CD2 1 
ATOM 4240 C CE1 . PHE B 1 366 ? 140.022 166.607 146.531 1.00 7.50  ? 366 PHE B CE1 1 
ATOM 4241 C CE2 . PHE B 1 366 ? 141.262 164.610 146.122 1.00 3.25  ? 366 PHE B CE2 1 
ATOM 4242 C CZ  . PHE B 1 366 ? 141.196 165.891 146.629 1.00 2.89  ? 366 PHE B CZ  1 
ATOM 4243 N N   . TYR B 1 367 ? 136.610 163.107 141.532 1.00 7.08  ? 367 TYR B N   1 
ATOM 4244 C CA  . TYR B 1 367 ? 135.557 162.363 140.835 1.00 5.51  ? 367 TYR B CA  1 
ATOM 4245 C C   . TYR B 1 367 ? 134.283 163.194 140.703 1.00 3.47  ? 367 TYR B C   1 
ATOM 4246 O O   . TYR B 1 367 ? 133.173 162.721 140.955 1.00 6.84  ? 367 TYR B O   1 
ATOM 4247 C CB  . TYR B 1 367 ? 135.253 161.034 141.530 1.00 3.59  ? 367 TYR B CB  1 
ATOM 4248 C CG  . TYR B 1 367 ? 136.449 160.293 142.087 1.00 5.58  ? 367 TYR B CG  1 
ATOM 4249 C CD1 . TYR B 1 367 ? 136.880 160.508 143.389 1.00 2.84  ? 367 TYR B CD1 1 
ATOM 4250 C CD2 . TYR B 1 367 ? 137.129 159.359 141.319 1.00 6.39  ? 367 TYR B CD2 1 
ATOM 4251 C CE1 . TYR B 1 367 ? 137.964 159.827 143.903 1.00 0.57  ? 367 TYR B CE1 1 
ATOM 4252 C CE2 . TYR B 1 367 ? 138.216 158.672 141.826 1.00 4.10  ? 367 TYR B CE2 1 
ATOM 4253 C CZ  . TYR B 1 367 ? 138.628 158.911 143.117 1.00 7.89  ? 367 TYR B CZ  1 
ATOM 4254 O OH  . TYR B 1 367 ? 139.707 158.228 143.629 1.00 15.25 ? 367 TYR B OH  1 
ATOM 4255 N N   . TYR B 1 368 ? 134.451 164.456 140.302 1.00 0.00  ? 368 TYR B N   1 
ATOM 4256 C CA  . TYR B 1 368 ? 133.329 165.388 140.343 1.00 0.86  ? 368 TYR B CA  1 
ATOM 4257 C C   . TYR B 1 368 ? 132.221 165.000 139.369 1.00 1.72  ? 368 TYR B C   1 
ATOM 4258 O O   . TYR B 1 368 ? 131.040 165.188 139.680 1.00 7.92  ? 368 TYR B O   1 
ATOM 4259 C CB  . TYR B 1 368 ? 133.824 166.819 140.095 1.00 1.91  ? 368 TYR B CB  1 
ATOM 4260 C CG  . TYR B 1 368 ? 134.458 167.082 138.747 1.00 3.29  ? 368 TYR B CG  1 
ATOM 4261 C CD1 . TYR B 1 368 ? 133.682 167.320 137.621 1.00 4.47  ? 368 TYR B CD1 1 
ATOM 4262 C CD2 . TYR B 1 368 ? 135.836 167.164 138.617 1.00 4.28  ? 368 TYR B CD2 1 
ATOM 4263 C CE1 . TYR B 1 368 ? 134.264 167.584 136.396 1.00 4.49  ? 368 TYR B CE1 1 
ATOM 4264 C CE2 . TYR B 1 368 ? 136.427 167.424 137.397 1.00 4.94  ? 368 TYR B CE2 1 
ATOM 4265 C CZ  . TYR B 1 368 ? 135.636 167.636 136.291 1.00 6.22  ? 368 TYR B CZ  1 
ATOM 4266 O OH  . TYR B 1 368 ? 136.221 167.898 135.074 1.00 8.70  ? 368 TYR B OH  1 
ATOM 4267 N N   . LYS B 1 369 ? 132.568 164.452 138.203 1.00 0.15  ? 369 LYS B N   1 
ATOM 4268 C CA  . LYS B 1 369 ? 131.542 163.992 137.271 1.00 2.43  ? 369 LYS B CA  1 
ATOM 4269 C C   . LYS B 1 369 ? 130.709 162.871 137.879 1.00 6.49  ? 369 LYS B C   1 
ATOM 4270 O O   . LYS B 1 369 ? 129.471 162.912 137.849 1.00 9.72  ? 369 LYS B O   1 
ATOM 4271 C CB  . LYS B 1 369 ? 132.189 163.536 135.961 1.00 3.26  ? 369 LYS B CB  1 
ATOM 4272 C CG  . LYS B 1 369 ? 132.904 164.609 135.118 1.00 2.56  ? 369 LYS B CG  1 
ATOM 4273 C CD  . LYS B 1 369 ? 131.985 165.591 134.352 1.00 6.47  ? 369 LYS B CD  1 
ATOM 4274 C CE  . LYS B 1 369 ? 131.112 166.504 135.205 1.00 3.79  ? 369 LYS B CE  1 
ATOM 4275 N NZ  . LYS B 1 369 ? 130.589 167.658 134.425 1.00 6.85  ? 369 LYS B NZ  1 
ATOM 4276 N N   . SER B 1 370 ? 131.377 161.865 138.449 1.00 0.05  ? 370 SER B N   1 
ATOM 4277 C CA  . SER B 1 370 ? 130.665 160.763 139.085 1.00 4.00  ? 370 SER B CA  1 
ATOM 4278 C C   . SER B 1 370 ? 129.834 161.254 140.261 1.00 2.39  ? 370 SER B C   1 
ATOM 4279 O O   . SER B 1 370 ? 128.694 160.816 140.451 1.00 4.37  ? 370 SER B O   1 
ATOM 4280 C CB  . SER B 1 370 ? 131.655 159.690 139.540 1.00 2.29  ? 370 SER B CB  1 
ATOM 4281 O OG  . SER B 1 370 ? 132.285 159.074 138.432 1.00 8.47  ? 370 SER B OG  1 
ATOM 4282 N N   . ARG B 1 371 ? 130.388 162.168 141.059 1.00 1.81  ? 371 ARG B N   1 
ATOM 4283 C CA  . ARG B 1 371 ? 129.667 162.680 142.220 1.00 3.14  ? 371 ARG B CA  1 
ATOM 4284 C C   . ARG B 1 371 ? 128.412 163.441 141.809 1.00 0.68  ? 371 ARG B C   1 
ATOM 4285 O O   . ARG B 1 371 ? 127.352 163.273 142.418 1.00 0.00  ? 371 ARG B O   1 
ATOM 4286 C CB  . ARG B 1 371 ? 130.588 163.567 143.053 1.00 1.51  ? 371 ARG B CB  1 
ATOM 4287 C CG  . ARG B 1 371 ? 131.704 162.809 143.748 1.00 3.10  ? 371 ARG B CG  1 
ATOM 4288 C CD  . ARG B 1 371 ? 132.493 163.705 144.681 1.00 3.05  ? 371 ARG B CD  1 
ATOM 4289 N NE  . ARG B 1 371 ? 133.119 164.829 143.991 1.00 2.65  ? 371 ARG B NE  1 
ATOM 4290 C CZ  . ARG B 1 371 ? 132.673 166.077 144.030 1.00 0.88  ? 371 ARG B CZ  1 
ATOM 4291 N NH1 . ARG B 1 371 ? 131.581 166.400 144.702 1.00 2.72  ? 371 ARG B NH1 1 
ATOM 4292 N NH2 . ARG B 1 371 ? 133.340 167.024 143.378 1.00 0.00  ? 371 ARG B NH2 1 
ATOM 4293 N N   . PHE B 1 372 ? 128.509 164.281 140.775 1.00 1.89  ? 372 PHE B N   1 
ATOM 4294 C CA  . PHE B 1 372 ? 127.340 165.040 140.334 1.00 2.63  ? 372 PHE B CA  1 
ATOM 4295 C C   . PHE B 1 372 ? 126.292 164.127 139.706 1.00 3.30  ? 372 PHE B C   1 
ATOM 4296 O O   . PHE B 1 372 ? 125.084 164.320 139.912 1.00 0.97  ? 372 PHE B O   1 
ATOM 4297 C CB  . PHE B 1 372 ? 127.758 166.141 139.357 1.00 4.61  ? 372 PHE B CB  1 
ATOM 4298 C CG  . PHE B 1 372 ? 128.756 167.121 139.922 1.00 3.82  ? 372 PHE B CG  1 
ATOM 4299 C CD1 . PHE B 1 372 ? 128.954 167.232 141.291 1.00 3.75  ? 372 PHE B CD1 1 
ATOM 4300 C CD2 . PHE B 1 372 ? 129.497 167.934 139.078 1.00 6.12  ? 372 PHE B CD2 1 
ATOM 4301 C CE1 . PHE B 1 372 ? 129.869 168.132 141.805 1.00 2.76  ? 372 PHE B CE1 1 
ATOM 4302 C CE2 . PHE B 1 372 ? 130.415 168.837 139.588 1.00 7.76  ? 372 PHE B CE2 1 
ATOM 4303 C CZ  . PHE B 1 372 ? 130.601 168.935 140.954 1.00 1.54  ? 372 PHE B CZ  1 
ATOM 4304 N N   . TRP B 1 373 ? 126.732 163.120 138.944 1.00 0.00  ? 373 TRP B N   1 
ATOM 4305 C CA  . TRP B 1 373 ? 125.791 162.143 138.409 1.00 0.39  ? 373 TRP B CA  1 
ATOM 4306 C C   . TRP B 1 373 ? 125.068 161.409 139.533 1.00 1.36  ? 373 TRP B C   1 
ATOM 4307 O O   . TRP B 1 373 ? 123.846 161.217 139.477 1.00 2.00  ? 373 TRP B O   1 
ATOM 4308 C CB  . TRP B 1 373 ? 126.528 161.157 137.499 1.00 1.26  ? 373 TRP B CB  1 
ATOM 4309 C CG  . TRP B 1 373 ? 125.673 160.048 136.968 1.00 0.60  ? 373 TRP B CG  1 
ATOM 4310 C CD1 . TRP B 1 373 ? 124.926 160.065 135.828 1.00 2.48  ? 373 TRP B CD1 1 
ATOM 4311 C CD2 . TRP B 1 373 ? 125.485 158.751 137.550 1.00 0.51  ? 373 TRP B CD2 1 
ATOM 4312 N NE1 . TRP B 1 373 ? 124.281 158.865 135.665 1.00 3.85  ? 373 TRP B NE1 1 
ATOM 4313 C CE2 . TRP B 1 373 ? 124.608 158.041 136.708 1.00 0.08  ? 373 TRP B CE2 1 
ATOM 4314 C CE3 . TRP B 1 373 ? 125.969 158.125 138.702 1.00 0.00  ? 373 TRP B CE3 1 
ATOM 4315 C CZ2 . TRP B 1 373 ? 124.205 156.735 136.981 1.00 0.90  ? 373 TRP B CZ2 1 
ATOM 4316 C CZ3 . TRP B 1 373 ? 125.570 156.830 138.970 1.00 3.07  ? 373 TRP B CZ3 1 
ATOM 4317 C CH2 . TRP B 1 373 ? 124.698 156.147 138.113 1.00 3.66  ? 373 TRP B CH2 1 
ATOM 4318 N N   . LEU B 1 374 ? 125.806 161.011 140.572 1.00 0.00  ? 374 LEU B N   1 
ATOM 4319 C CA  . LEU B 1 374 ? 125.194 160.325 141.705 1.00 0.00  ? 374 LEU B CA  1 
ATOM 4320 C C   . LEU B 1 374 ? 124.239 161.240 142.457 1.00 0.00  ? 374 LEU B C   1 
ATOM 4321 O O   . LEU B 1 374 ? 123.199 160.789 142.943 1.00 0.00  ? 374 LEU B O   1 
ATOM 4322 C CB  . LEU B 1 374 ? 126.277 159.789 142.642 1.00 0.00  ? 374 LEU B CB  1 
ATOM 4323 C CG  . LEU B 1 374 ? 125.788 158.986 143.850 1.00 0.00  ? 374 LEU B CG  1 
ATOM 4324 C CD1 . LEU B 1 374 ? 125.032 157.742 143.402 1.00 0.00  ? 374 LEU B CD1 1 
ATOM 4325 C CD2 . LEU B 1 374 ? 126.946 158.619 144.764 1.00 0.00  ? 374 LEU B CD2 1 
ATOM 4326 N N   . LEU B 1 375 ? 124.585 162.523 142.581 1.00 1.73  ? 375 LEU B N   1 
ATOM 4327 C CA  . LEU B 1 375 ? 123.706 163.473 143.252 1.00 0.37  ? 375 LEU B CA  1 
ATOM 4328 C C   . LEU B 1 375 ? 122.385 163.608 142.507 1.00 0.39  ? 375 LEU B C   1 
ATOM 4329 O O   . LEU B 1 375 ? 121.304 163.582 143.114 1.00 0.00  ? 375 LEU B O   1 
ATOM 4330 C CB  . LEU B 1 375 ? 124.403 164.828 143.367 1.00 0.00  ? 375 LEU B CB  1 
ATOM 4331 C CG  . LEU B 1 375 ? 125.381 165.006 144.529 1.00 1.44  ? 375 LEU B CG  1 
ATOM 4332 C CD1 . LEU B 1 375 ? 126.152 166.309 144.385 1.00 2.05  ? 375 LEU B CD1 1 
ATOM 4333 C CD2 . LEU B 1 375 ? 124.644 164.964 145.854 1.00 3.95  ? 375 LEU B CD2 1 
ATOM 4334 N N   . LYS B 1 376 ? 122.456 163.735 141.180 1.00 0.00  ? 376 LYS B N   1 
ATOM 4335 C CA  . LYS B 1 376 ? 121.235 163.809 140.386 1.00 0.00  ? 376 LYS B CA  1 
ATOM 4336 C C   . LYS B 1 376 ? 120.424 162.524 140.499 1.00 0.99  ? 376 LYS B C   1 
ATOM 4337 O O   . LYS B 1 376 ? 119.193 162.568 140.608 1.00 0.64  ? 376 LYS B O   1 
ATOM 4338 C CB  . LYS B 1 376 ? 121.573 164.112 138.927 1.00 0.90  ? 376 LYS B CB  1 
ATOM 4339 C CG  . LYS B 1 376 ? 121.894 165.574 138.671 1.00 1.49  ? 376 LYS B CG  1 
ATOM 4340 C CD  . LYS B 1 376 ? 121.818 165.908 137.194 1.00 3.51  ? 376 LYS B CD  1 
ATOM 4341 C CE  . LYS B 1 376 ? 123.163 165.716 136.518 1.00 2.77  ? 376 LYS B CE  1 
ATOM 4342 N NZ  . LYS B 1 376 ? 124.260 166.369 137.280 1.00 4.08  ? 376 LYS B NZ  1 
ATOM 4343 N N   . LEU B 1 377 ? 121.096 161.367 140.484 1.00 0.00  ? 377 LEU B N   1 
ATOM 4344 C CA  . LEU B 1 377 ? 120.379 160.100 140.608 1.00 0.00  ? 377 LEU B CA  1 
ATOM 4345 C C   . LEU B 1 377 ? 119.701 159.968 141.969 1.00 0.00  ? 377 LEU B C   1 
ATOM 4346 O O   . LEU B 1 377 ? 118.568 159.489 142.055 1.00 0.00  ? 377 LEU B O   1 
ATOM 4347 C CB  . LEU B 1 377 ? 121.327 158.927 140.365 1.00 0.00  ? 377 LEU B CB  1 
ATOM 4348 C CG  . LEU B 1 377 ? 120.659 157.550 140.302 1.00 0.00  ? 377 LEU B CG  1 
ATOM 4349 C CD1 . LEU B 1 377 ? 119.494 157.551 139.324 1.00 0.00  ? 377 LEU B CD1 1 
ATOM 4350 C CD2 . LEU B 1 377 ? 121.665 156.474 139.935 1.00 0.00  ? 377 LEU B CD2 1 
ATOM 4351 N N   . LEU B 1 378 ? 120.378 160.382 143.043 1.00 0.00  ? 378 LEU B N   1 
ATOM 4352 C CA  . LEU B 1 378 ? 119.774 160.320 144.371 1.00 1.88  ? 378 LEU B CA  1 
ATOM 4353 C C   . LEU B 1 378 ? 118.565 161.240 144.472 1.00 3.81  ? 378 LEU B C   1 
ATOM 4354 O O   . LEU B 1 378 ? 117.530 160.861 145.039 1.00 1.31  ? 378 LEU B O   1 
ATOM 4355 C CB  . LEU B 1 378 ? 120.809 160.681 145.437 1.00 1.07  ? 378 LEU B CB  1 
ATOM 4356 C CG  . LEU B 1 378 ? 121.902 159.654 145.723 1.00 0.82  ? 378 LEU B CG  1 
ATOM 4357 C CD1 . LEU B 1 378 ? 123.088 160.327 146.389 1.00 1.71  ? 378 LEU B CD1 1 
ATOM 4358 C CD2 . LEU B 1 378 ? 121.366 158.529 146.591 1.00 0.00  ? 378 LEU B CD2 1 
ATOM 4359 N N   . PHE B 1 379 ? 118.674 162.455 143.924 1.00 0.25  ? 379 PHE B N   1 
ATOM 4360 C CA  . PHE B 1 379 ? 117.523 163.352 143.907 1.00 0.00  ? 379 PHE B CA  1 
ATOM 4361 C C   . PHE B 1 379 ? 116.369 162.743 143.123 1.00 0.00  ? 379 PHE B C   1 
ATOM 4362 O O   . PHE B 1 379 ? 115.209 162.826 143.543 1.00 3.13  ? 379 PHE B O   1 
ATOM 4363 C CB  . PHE B 1 379 ? 117.917 164.707 143.316 1.00 0.00  ? 379 PHE B CB  1 
ATOM 4364 C CG  . PHE B 1 379 ? 116.748 165.609 143.039 1.00 0.00  ? 379 PHE B CG  1 
ATOM 4365 C CD1 . PHE B 1 379 ? 116.215 166.400 144.043 1.00 2.63  ? 379 PHE B CD1 1 
ATOM 4366 C CD2 . PHE B 1 379 ? 116.186 165.673 141.775 1.00 0.19  ? 379 PHE B CD2 1 
ATOM 4367 C CE1 . PHE B 1 379 ? 115.140 167.232 143.793 1.00 3.07  ? 379 PHE B CE1 1 
ATOM 4368 C CE2 . PHE B 1 379 ? 115.111 166.500 141.520 1.00 1.77  ? 379 PHE B CE2 1 
ATOM 4369 C CZ  . PHE B 1 379 ? 114.588 167.282 142.530 1.00 1.37  ? 379 PHE B CZ  1 
ATOM 4370 N N   . ARG B 1 380 ? 116.671 162.129 141.978 1.00 2.45  ? 380 ARG B N   1 
ATOM 4371 C CA  . ARG B 1 380 ? 115.636 161.491 141.173 1.00 1.25  ? 380 ARG B CA  1 
ATOM 4372 C C   . ARG B 1 380 ? 114.980 160.341 141.931 1.00 1.77  ? 380 ARG B C   1 
ATOM 4373 O O   . ARG B 1 380 ? 113.761 160.150 141.855 1.00 0.32  ? 380 ARG B O   1 
ATOM 4374 C CB  . ARG B 1 380 ? 116.244 161.000 139.858 1.00 1.02  ? 380 ARG B CB  1 
ATOM 4375 C CG  . ARG B 1 380 ? 115.565 161.548 138.619 1.00 3.18  ? 380 ARG B CG  1 
ATOM 4376 C CD  . ARG B 1 380 ? 116.137 160.991 137.316 1.00 2.14  ? 380 ARG B CD  1 
ATOM 4377 N NE  . ARG B 1 380 ? 117.570 160.730 137.371 1.00 2.14  ? 380 ARG B NE  1 
ATOM 4378 C CZ  . ARG B 1 380 ? 118.508 161.668 137.326 1.00 3.47  ? 380 ARG B CZ  1 
ATOM 4379 N NH1 . ARG B 1 380 ? 118.199 162.953 137.261 1.00 5.18  ? 380 ARG B NH1 1 
ATOM 4380 N NH2 . ARG B 1 380 ? 119.787 161.308 137.345 1.00 3.14  ? 380 ARG B NH2 1 
ATOM 4381 N N   . VAL B 1 381 ? 115.778 159.568 142.670 1.00 1.03  ? 381 VAL B N   1 
ATOM 4382 C CA  . VAL B 1 381 ? 115.265 158.391 143.363 1.00 0.00  ? 381 VAL B CA  1 
ATOM 4383 C C   . VAL B 1 381 ? 114.378 158.793 144.532 1.00 0.00  ? 381 VAL B C   1 
ATOM 4384 O O   . VAL B 1 381 ? 113.300 158.223 144.732 1.00 0.00  ? 381 VAL B O   1 
ATOM 4385 C CB  . VAL B 1 381 ? 116.431 157.491 143.818 1.00 3.49  ? 381 VAL B CB  1 
ATOM 4386 C CG1 . VAL B 1 381 ? 116.030 156.652 145.028 1.00 0.78  ? 381 VAL B CG1 1 
ATOM 4387 C CG2 . VAL B 1 381 ? 116.889 156.596 142.680 1.00 0.39  ? 381 VAL B CG2 1 
ATOM 4388 N N   . PHE B 1 382 ? 114.809 159.771 145.329 1.00 4.89  ? 382 PHE B N   1 
ATOM 4389 C CA  . PHE B 1 382 ? 114.053 160.090 146.534 1.00 4.19  ? 382 PHE B CA  1 
ATOM 4390 C C   . PHE B 1 382 ? 112.773 160.866 146.245 1.00 3.39  ? 382 PHE B C   1 
ATOM 4391 O O   . PHE B 1 382 ? 111.861 160.856 147.077 1.00 2.89  ? 382 PHE B O   1 
ATOM 4392 C CB  . PHE B 1 382 ? 114.937 160.841 147.528 1.00 2.47  ? 382 PHE B CB  1 
ATOM 4393 C CG  . PHE B 1 382 ? 115.646 159.932 148.491 1.00 2.53  ? 382 PHE B CG  1 
ATOM 4394 C CD1 . PHE B 1 382 ? 115.022 159.512 149.654 1.00 3.66  ? 382 PHE B CD1 1 
ATOM 4395 C CD2 . PHE B 1 382 ? 116.920 159.467 148.215 1.00 2.26  ? 382 PHE B CD2 1 
ATOM 4396 C CE1 . PHE B 1 382 ? 115.665 158.663 150.534 1.00 2.10  ? 382 PHE B CE1 1 
ATOM 4397 C CE2 . PHE B 1 382 ? 117.568 158.619 149.093 1.00 0.84  ? 382 PHE B CE2 1 
ATOM 4398 C CZ  . PHE B 1 382 ? 116.939 158.215 150.252 1.00 0.90  ? 382 PHE B CZ  1 
ATOM 4399 N N   . THR B 1 383 ? 112.685 161.533 145.100 1.00 1.66  ? 383 THR B N   1 
ATOM 4400 C CA  . THR B 1 383 ? 111.411 162.023 144.568 1.00 1.00  ? 383 THR B CA  1 
ATOM 4401 C C   . THR B 1 383 ? 110.831 161.029 143.566 1.00 4.50  ? 383 THR B C   1 
ATOM 4402 O O   . THR B 1 383 ? 110.491 161.375 142.436 1.00 8.21  ? 383 THR B O   1 
ATOM 4403 C CB  . THR B 1 383 ? 111.594 163.399 143.936 1.00 4.39  ? 383 THR B CB  1 
ATOM 4404 O OG1 . THR B 1 383 ? 112.278 163.269 142.683 1.00 4.90  ? 383 THR B OG1 1 
ATOM 4405 C CG2 . THR B 1 383 ? 112.402 164.300 144.854 1.00 0.00  ? 383 THR B CG2 1 
ATOM 4406 N N   . ALA B 1 384 ? 110.703 159.776 144.003 1.00 6.92  ? 384 ALA B N   1 
ATOM 4407 C CA  . ALA B 1 384 ? 110.424 158.672 143.085 1.00 0.10  ? 384 ALA B CA  1 
ATOM 4408 C C   . ALA B 1 384 ? 109.150 158.808 142.255 1.00 8.73  ? 384 ALA B C   1 
ATOM 4409 O O   . ALA B 1 384 ? 109.175 158.384 141.086 1.00 11.25 ? 384 ALA B O   1 
ATOM 4410 C CB  . ALA B 1 384 ? 110.405 157.352 143.864 1.00 1.84  ? 384 ALA B CB  1 
ATOM 4411 N N   . PRO B 1 385 ? 108.015 159.308 142.773 1.00 6.11  ? 385 PRO B N   1 
ATOM 4412 C CA  . PRO B 1 385 ? 106.802 159.337 141.931 1.00 1.12  ? 385 PRO B CA  1 
ATOM 4413 C C   . PRO B 1 385 ? 106.973 160.088 140.619 1.00 5.99  ? 385 PRO B C   1 
ATOM 4414 O O   . PRO B 1 385 ? 106.421 159.662 139.598 1.00 5.60  ? 385 PRO B O   1 
ATOM 4415 C CB  . PRO B 1 385 ? 105.763 160.008 142.838 1.00 1.81  ? 385 PRO B CB  1 
ATOM 4416 C CG  . PRO B 1 385 ? 106.219 159.721 144.206 1.00 4.45  ? 385 PRO B CG  1 
ATOM 4417 C CD  . PRO B 1 385 ? 107.716 159.691 144.165 1.00 0.10  ? 385 PRO B CD  1 
ATOM 4418 N N   . PHE B 1 386 ? 107.718 161.189 140.608 1.00 5.71  ? 386 PHE B N   1 
ATOM 4419 C CA  . PHE B 1 386 ? 108.020 161.888 139.366 1.00 5.21  ? 386 PHE B CA  1 
ATOM 4420 C C   . PHE B 1 386 ? 109.062 162.194 138.290 1.00 8.89  ? 386 PHE B C   1 
ATOM 4421 O O   . PHE B 1 386 ? 108.945 163.174 137.551 1.00 16.03 ? 386 PHE B O   1 
ATOM 4422 C CB  . PHE B 1 386 ? 108.223 163.375 139.635 1.00 4.48  ? 386 PHE B CB  1 
ATOM 4423 C CG  . PHE B 1 386 ? 107.303 163.929 140.683 1.00 7.38  ? 386 PHE B CG  1 
ATOM 4424 C CD1 . PHE B 1 386 ? 105.954 164.096 140.421 1.00 7.77  ? 386 PHE B CD1 1 
ATOM 4425 C CD2 . PHE B 1 386 ? 107.785 164.276 141.934 1.00 8.22  ? 386 PHE B CD2 1 
ATOM 4426 C CE1 . PHE B 1 386 ? 105.103 164.604 141.385 1.00 7.17  ? 386 PHE B CE1 1 
ATOM 4427 C CE2 . PHE B 1 386 ? 106.939 164.781 142.902 1.00 8.57  ? 386 PHE B CE2 1 
ATOM 4428 C CZ  . PHE B 1 386 ? 105.596 164.945 142.626 1.00 8.13  ? 386 PHE B CZ  1 
ATOM 4429 N N   . HIS B 1 387 ? 110.096 161.357 138.184 1.00 4.38  ? 387 HIS B N   1 
ATOM 4430 C CA  . HIS B 1 387 ? 111.045 161.427 137.073 1.00 5.17  ? 387 HIS B CA  1 
ATOM 4431 C C   . HIS B 1 387 ? 110.435 160.049 136.796 1.00 7.54  ? 387 HIS B C   1 
ATOM 4432 O O   . HIS B 1 387 ? 109.809 159.432 137.661 1.00 11.96 ? 387 HIS B O   1 
ATOM 4433 C CB  . HIS B 1 387 ? 112.190 161.684 138.057 1.00 4.14  ? 387 HIS B CB  1 
ATOM 4434 C CG  . HIS B 1 387 ? 112.279 163.101 138.523 1.00 6.24  ? 387 HIS B CG  1 
ATOM 4435 N ND1 . HIS B 1 387 ? 112.320 163.445 139.856 1.00 5.35  ? 387 HIS B ND1 1 
ATOM 4436 C CD2 . HIS B 1 387 ? 112.331 164.264 137.832 1.00 5.60  ? 387 HIS B CD2 1 
ATOM 4437 C CE1 . HIS B 1 387 ? 112.396 164.759 139.967 1.00 7.81  ? 387 HIS B CE1 1 
ATOM 4438 N NE2 . HIS B 1 387 ? 112.405 165.280 138.754 1.00 8.90  ? 387 HIS B NE2 1 
ATOM 4439 N N   . LYS B 1 388 ? 110.605 159.611 135.543 1.00 10.91 ? 388 LYS B N   1 
ATOM 4440 C CA  . LYS B 1 388 ? 110.009 158.376 135.036 1.00 1.16  ? 388 LYS B CA  1 
ATOM 4441 C C   . LYS B 1 388 ? 111.255 157.497 135.091 1.00 1.89  ? 388 LYS B C   1 
ATOM 4442 O O   . LYS B 1 388 ? 112.378 157.961 134.879 1.00 5.22  ? 388 LYS B O   1 
ATOM 4443 C CB  . LYS B 1 388 ? 109.480 158.463 133.597 1.00 5.97  ? 388 LYS B CB  1 
ATOM 4444 C CG  . LYS B 1 388 ? 110.466 158.055 132.508 1.00 3.97  ? 388 LYS B CG  1 
ATOM 4445 C CD  . LYS B 1 388 ? 109.769 157.854 131.173 1.00 6.45  ? 388 LYS B CD  1 
ATOM 4446 C CE  . LYS B 1 388 ? 110.615 157.021 130.223 1.00 8.81  ? 388 LYS B CE  1 
ATOM 4447 N NZ  . LYS B 1 388 ? 110.648 155.588 130.621 1.00 10.28 ? 388 LYS B NZ  1 
ATOM 4448 N N   . VAL B 1 389 ? 111.036 156.220 135.382 1.00 4.17  ? 389 VAL B N   1 
ATOM 4449 C CA  . VAL B 1 389 ? 112.070 155.346 135.926 1.00 1.55  ? 389 VAL B CA  1 
ATOM 4450 C C   . VAL B 1 389 ? 112.932 154.782 134.804 1.00 1.74  ? 389 VAL B C   1 
ATOM 4451 O O   . VAL B 1 389 ? 112.454 154.012 133.966 1.00 10.33 ? 389 VAL B O   1 
ATOM 4452 C CB  . VAL B 1 389 ? 111.446 154.213 136.753 1.00 1.19  ? 389 VAL B CB  1 
ATOM 4453 C CG1 . VAL B 1 389 ? 112.529 153.369 137.410 1.00 0.80  ? 389 VAL B CG1 1 
ATOM 4454 C CG2 . VAL B 1 389 ? 110.491 154.780 137.790 1.00 1.76  ? 389 VAL B CG2 1 
ATOM 4455 N N   . GLY B 1 390 ? 114.212 155.158 134.799 1.00 0.00  ? 390 GLY B N   1 
ATOM 4456 C CA  . GLY B 1 390 ? 115.209 154.463 134.016 1.00 0.96  ? 390 GLY B CA  1 
ATOM 4457 C C   . GLY B 1 390 ? 115.836 153.331 134.813 1.00 2.48  ? 390 GLY B C   1 
ATOM 4458 O O   . GLY B 1 390 ? 115.449 153.040 135.943 1.00 0.00  ? 390 GLY B O   1 
ATOM 4459 N N   . PHE B 1 391 ? 116.831 152.684 134.202 1.00 0.00  ? 391 PHE B N   1 
ATOM 4460 C CA  . PHE B 1 391 ? 117.486 151.559 134.866 1.00 1.14  ? 391 PHE B CA  1 
ATOM 4461 C C   . PHE B 1 391 ? 118.216 151.995 136.134 1.00 0.82  ? 391 PHE B C   1 
ATOM 4462 O O   . PHE B 1 391 ? 118.106 151.347 137.183 1.00 0.00  ? 391 PHE B O   1 
ATOM 4463 C CB  . PHE B 1 391 ? 118.452 150.854 133.909 1.00 0.00  ? 391 PHE B CB  1 
ATOM 4464 C CG  . PHE B 1 391 ? 119.363 149.863 134.590 1.00 0.00  ? 391 PHE B CG  1 
ATOM 4465 C CD1 . PHE B 1 391 ? 118.975 148.549 134.781 1.00 0.00  ? 391 PHE B CD1 1 
ATOM 4466 C CD2 . PHE B 1 391 ? 120.619 150.250 135.026 1.00 0.00  ? 391 PHE B CD2 1 
ATOM 4467 C CE1 . PHE B 1 391 ? 119.809 147.648 135.417 1.00 0.00  ? 391 PHE B CE1 1 
ATOM 4468 C CE2 . PHE B 1 391 ? 121.456 149.355 135.655 1.00 0.00  ? 391 PHE B CE2 1 
ATOM 4469 C CZ  . PHE B 1 391 ? 121.053 148.053 135.851 1.00 0.00  ? 391 PHE B CZ  1 
ATOM 4470 N N   . ALA B 1 392 ? 118.982 153.084 136.050 1.00 0.00  ? 392 ALA B N   1 
ATOM 4471 C CA  . ALA B 1 392 ? 119.816 153.491 137.176 1.00 0.00  ? 392 ALA B CA  1 
ATOM 4472 C C   . ALA B 1 392 ? 118.968 153.852 138.388 1.00 0.00  ? 392 ALA B C   1 
ATOM 4473 O O   . ALA B 1 392 ? 119.351 153.567 139.528 1.00 0.00  ? 392 ALA B O   1 
ATOM 4474 C CB  . ALA B 1 392 ? 120.711 154.661 136.767 1.00 0.00  ? 392 ALA B CB  1 
ATOM 4475 N N   . ASP B 1 393 ? 117.802 154.461 138.155 1.00 0.95  ? 393 ASP B N   1 
ATOM 4476 C CA  . ASP B 1 393 ? 116.911 154.823 139.253 1.00 2.69  ? 393 ASP B CA  1 
ATOM 4477 C C   . ASP B 1 393 ? 116.469 153.595 140.044 1.00 0.00  ? 393 ASP B C   1 
ATOM 4478 O O   . ASP B 1 393 ? 116.626 153.549 141.273 1.00 0.00  ? 393 ASP B O   1 
ATOM 4479 C CB  . ASP B 1 393 ? 115.693 155.579 138.718 1.00 0.00  ? 393 ASP B CB  1 
ATOM 4480 C CG  . ASP B 1 393 ? 116.069 156.721 137.801 1.00 1.27  ? 393 ASP B CG  1 
ATOM 4481 O OD1 . ASP B 1 393 ? 116.792 156.477 136.815 1.00 7.29  ? 393 ASP B OD1 1 
ATOM 4482 O OD2 . ASP B 1 393 ? 115.635 157.862 138.063 1.00 9.08  ? 393 ASP B OD2 1 
ATOM 4483 N N   . PHE B 1 394 ? 115.810 152.733 139.180 1.00 0.00  ? 394 PHE B N   1 
ATOM 4484 C CA  . PHE B 1 394 ? 115.377 151.395 139.582 1.00 1.89  ? 394 PHE B CA  1 
ATOM 4485 C C   . PHE B 1 394 ? 116.473 150.634 140.493 1.00 0.00  ? 394 PHE B C   1 
ATOM 4486 O O   . PHE B 1 394 ? 116.149 150.267 141.575 1.00 0.00  ? 394 PHE B O   1 
ATOM 4487 C CB  . PHE B 1 394 ? 114.863 150.506 138.394 1.00 1.81  ? 394 PHE B CB  1 
ATOM 4488 C CG  . PHE B 1 394 ? 115.198 149.038 138.561 1.00 0.08  ? 394 PHE B CG  1 
ATOM 4489 C CD1 . PHE B 1 394 ? 114.479 148.250 139.451 1.00 0.94  ? 394 PHE B CD1 1 
ATOM 4490 C CD2 . PHE B 1 394 ? 116.307 148.480 137.942 1.00 3.25  ? 394 PHE B CD2 1 
ATOM 4491 C CE1 . PHE B 1 394 ? 114.811 146.926 139.616 1.00 0.09  ? 394 PHE B CE1 1 
ATOM 4492 C CE2 . PHE B 1 394 ? 116.659 147.176 138.160 1.00 7.25  ? 394 PHE B CE2 1 
ATOM 4493 C CZ  . PHE B 1 394 ? 115.925 146.394 139.012 1.00 1.87  ? 394 PHE B CZ  1 
ATOM 4494 N N   . TRP B 1 395 ? 117.665 150.606 140.003 1.00 0.00  ? 395 TRP B N   1 
ATOM 4495 C CA  . TRP B 1 395 ? 118.824 149.864 140.488 1.00 0.00  ? 395 TRP B CA  1 
ATOM 4496 C C   . TRP B 1 395 ? 119.354 150.467 141.782 1.00 0.00  ? 395 TRP B C   1 
ATOM 4497 O O   . TRP B 1 395 ? 119.639 149.741 142.739 1.00 0.00  ? 395 TRP B O   1 
ATOM 4498 C CB  . TRP B 1 395 ? 119.920 149.826 139.416 1.00 0.00  ? 395 TRP B CB  1 
ATOM 4499 C CG  . TRP B 1 395 ? 121.116 148.987 139.787 1.00 0.00  ? 395 TRP B CG  1 
ATOM 4500 C CD1 . TRP B 1 395 ? 121.270 147.646 139.587 1.00 0.00  ? 395 TRP B CD1 1 
ATOM 4501 C CD2 . TRP B 1 395 ? 122.314 149.433 140.437 1.00 0.00  ? 395 TRP B CD2 1 
ATOM 4502 N NE1 . TRP B 1 395 ? 122.487 147.231 140.065 1.00 0.00  ? 395 TRP B NE1 1 
ATOM 4503 C CE2 . TRP B 1 395 ? 123.148 148.308 140.593 1.00 0.00  ? 395 TRP B CE2 1 
ATOM 4504 C CE3 . TRP B 1 395 ? 122.763 150.674 140.898 1.00 0.00  ? 395 TRP B CE3 1 
ATOM 4505 C CZ2 . TRP B 1 395 ? 124.404 148.386 141.189 1.00 0.00  ? 395 TRP B CZ2 1 
ATOM 4506 C CZ3 . TRP B 1 395 ? 124.010 150.750 141.489 1.00 0.00  ? 395 TRP B CZ3 1 
ATOM 4507 C CH2 . TRP B 1 395 ? 124.815 149.612 141.632 1.00 0.00  ? 395 TRP B CH2 1 
ATOM 4508 N N   . LEU B 1 396 ? 119.465 151.797 141.841 1.00 0.00  ? 396 LEU B N   1 
ATOM 4509 C CA  . LEU B 1 396 ? 119.882 152.448 143.078 1.00 0.00  ? 396 LEU B CA  1 
ATOM 4510 C C   . LEU B 1 396 ? 118.840 152.266 144.176 1.00 0.00  ? 396 LEU B C   1 
ATOM 4511 O O   . LEU B 1 396 ? 119.193 152.081 145.347 1.00 0.00  ? 396 LEU B O   1 
ATOM 4512 C CB  . LEU B 1 396 ? 120.155 153.933 142.828 1.00 0.03  ? 396 LEU B CB  1 
ATOM 4513 C CG  . LEU B 1 396 ? 120.653 154.734 144.036 1.00 1.59  ? 396 LEU B CG  1 
ATOM 4514 C CD1 . LEU B 1 396 ? 122.015 154.231 144.492 1.00 0.00  ? 396 LEU B CD1 1 
ATOM 4515 C CD2 . LEU B 1 396 ? 120.697 156.230 143.737 1.00 0.52  ? 396 LEU B CD2 1 
ATOM 4516 N N   . ALA B 1 397 ? 117.552 152.307 143.821 1.00 0.00  ? 397 ALA B N   1 
ATOM 4517 C CA  . ALA B 1 397 ? 116.514 152.065 144.819 1.00 0.07  ? 397 ALA B CA  1 
ATOM 4518 C C   . ALA B 1 397 ? 116.608 150.651 145.393 1.00 0.15  ? 397 ALA B C   1 
ATOM 4519 O O   . ALA B 1 397 ? 116.431 150.449 146.599 1.00 1.22  ? 397 ALA B O   1 
ATOM 4520 C CB  . ALA B 1 397 ? 115.136 152.320 144.211 1.00 0.00  ? 397 ALA B CB  1 
ATOM 4521 N N   . ASP B 1 398 ? 116.895 149.660 144.546 1.00 0.00  ? 398 ASP B N   1 
ATOM 4522 C CA  . ASP B 1 398 ? 117.086 148.291 145.023 1.00 0.00  ? 398 ASP B CA  1 
ATOM 4523 C C   . ASP B 1 398 ? 118.328 148.170 145.905 1.00 0.00  ? 398 ASP B C   1 
ATOM 4524 O O   . ASP B 1 398 ? 118.299 147.485 146.940 1.00 1.82  ? 398 ASP B O   1 
ATOM 4525 C CB  . ASP B 1 398 ? 117.170 147.327 143.837 1.00 0.46  ? 398 ASP B CB  1 
ATOM 4526 C CG  . ASP B 1 398 ? 115.834 147.140 143.139 1.00 0.24  ? 398 ASP B CG  1 
ATOM 4527 O OD1 . ASP B 1 398 ? 114.797 147.515 143.717 1.00 0.52  ? 398 ASP B OD1 1 
ATOM 4528 O OD2 . ASP B 1 398 ? 115.821 146.608 142.010 1.00 1.19  ? 398 ASP B OD2 1 
ATOM 4529 N N   . GLN B 1 399 ? 119.431 148.821 145.511 1.00 0.00  ? 399 GLN B N   1 
ATOM 4530 C CA  . GLN B 1 399 ? 120.611 148.845 146.375 1.00 0.00  ? 399 GLN B CA  1 
ATOM 4531 C C   . GLN B 1 399 ? 120.260 149.420 147.744 1.00 3.52  ? 399 GLN B C   1 
ATOM 4532 O O   . GLN B 1 399 ? 120.732 148.928 148.775 1.00 0.00  ? 399 GLN B O   1 
ATOM 4533 C CB  . GLN B 1 399 ? 121.751 149.655 145.742 1.00 0.00  ? 399 GLN B CB  1 
ATOM 4534 C CG  . GLN B 1 399 ? 122.145 149.328 144.289 1.00 0.00  ? 399 GLN B CG  1 
ATOM 4535 C CD  . GLN B 1 399 ? 122.373 147.851 144.017 1.00 0.00  ? 399 GLN B CD  1 
ATOM 4536 O OE1 . GLN B 1 399 ? 123.342 147.265 144.491 1.00 0.00  ? 399 GLN B OE1 1 
ATOM 4537 N NE2 . GLN B 1 399 ? 121.486 147.250 143.232 1.00 0.00  ? 399 GLN B NE2 1 
ATOM 4538 N N   . LEU B 1 400 ? 119.426 150.465 147.768 1.00 0.00  ? 400 LEU B N   1 
ATOM 4539 C CA  . LEU B 1 400 ? 118.957 151.018 149.035 1.00 1.00  ? 400 LEU B CA  1 
ATOM 4540 C C   . LEU B 1 400 ? 118.128 150.000 149.807 1.00 0.00  ? 400 LEU B C   1 
ATOM 4541 O O   . LEU B 1 400 ? 118.229 149.908 151.035 1.00 0.00  ? 400 LEU B O   1 
ATOM 4542 C CB  . LEU B 1 400 ? 118.144 152.288 148.789 1.00 0.00  ? 400 LEU B CB  1 
ATOM 4543 C CG  . LEU B 1 400 ? 118.922 153.516 148.324 1.00 0.00  ? 400 LEU B CG  1 
ATOM 4544 C CD1 . LEU B 1 400 ? 117.997 154.714 148.201 1.00 1.10  ? 400 LEU B CD1 1 
ATOM 4545 C CD2 . LEU B 1 400 ? 120.075 153.812 149.268 1.00 1.05  ? 400 LEU B CD2 1 
ATOM 4546 N N   . ASN B 1 401 ? 117.286 149.240 149.102 1.00 0.47  ? 401 ASN B N   1 
ATOM 4547 C CA  . ASN B 1 401 ? 116.532 148.176 149.757 1.00 0.73  ? 401 ASN B CA  1 
ATOM 4548 C C   . ASN B 1 401 ? 117.461 147.172 150.422 1.00 0.00  ? 401 ASN B C   1 
ATOM 4549 O O   . ASN B 1 401 ? 117.094 146.555 151.427 1.00 2.65  ? 401 ASN B O   1 
ATOM 4550 C CB  . ASN B 1 401 ? 115.622 147.463 148.758 1.00 0.43  ? 401 ASN B CB  1 
ATOM 4551 C CG  . ASN B 1 401 ? 114.243 148.080 148.681 1.00 0.71  ? 401 ASN B CG  1 
ATOM 4552 O OD1 . ASN B 1 401 ? 113.278 147.537 149.213 1.00 0.00  ? 401 ASN B OD1 1 
ATOM 4553 N ND2 . ASN B 1 401 ? 114.143 149.219 148.009 1.00 0.00  ? 401 ASN B ND2 1 
ATOM 4554 N N   . SER B 1 402 ? 118.660 146.991 149.879 1.00 2.51  ? 402 SER B N   1 
ATOM 4555 C CA  . SER B 1 402 ? 119.667 146.174 150.544 1.00 1.84  ? 402 SER B CA  1 
ATOM 4556 C C   . SER B 1 402 ? 120.495 146.951 151.566 1.00 0.73  ? 402 SER B C   1 
ATOM 4557 O O   . SER B 1 402 ? 121.321 146.347 152.256 1.00 0.00  ? 402 SER B O   1 
ATOM 4558 C CB  . SER B 1 402 ? 120.597 145.533 149.512 1.00 1.10  ? 402 SER B CB  1 
ATOM 4559 O OG  . SER B 1 402 ? 121.711 144.929 150.140 1.00 2.10  ? 402 SER B OG  1 
ATOM 4560 N N   . LEU B 1 403 ? 120.297 148.264 151.686 1.00 0.00  ? 403 LEU B N   1 
ATOM 4561 C CA  . LEU B 1 403 ? 121.087 149.099 152.586 1.00 0.00  ? 403 LEU B CA  1 
ATOM 4562 C C   . LEU B 1 403 ? 120.217 149.856 153.587 1.00 0.61  ? 403 LEU B C   1 
ATOM 4563 O O   . LEU B 1 403 ? 120.604 150.923 154.066 1.00 0.00  ? 403 LEU B O   1 
ATOM 4564 C CB  . LEU B 1 403 ? 121.948 150.082 151.794 1.00 0.00  ? 403 LEU B CB  1 
ATOM 4565 C CG  . LEU B 1 403 ? 123.172 149.537 151.058 1.00 0.00  ? 403 LEU B CG  1 
ATOM 4566 C CD1 . LEU B 1 403 ? 123.742 150.592 150.123 1.00 1.98  ? 403 LEU B CD1 1 
ATOM 4567 C CD2 . LEU B 1 403 ? 124.227 149.066 152.041 1.00 2.17  ? 403 LEU B CD2 1 
ATOM 4568 N N   . SER B 1 404 ? 119.041 149.316 153.920 1.00 2.72  ? 404 SER B N   1 
ATOM 4569 C CA  . SER B 1 404 ? 118.120 150.037 154.796 1.00 2.12  ? 404 SER B CA  1 
ATOM 4570 C C   . SER B 1 404 ? 118.673 150.184 156.209 1.00 1.11  ? 404 SER B C   1 
ATOM 4571 O O   . SER B 1 404 ? 118.216 151.047 156.967 1.00 0.60  ? 404 SER B O   1 
ATOM 4572 C CB  . SER B 1 404 ? 116.763 149.332 154.834 1.00 1.68  ? 404 SER B CB  1 
ATOM 4573 O OG  . SER B 1 404 ? 116.844 148.104 155.536 1.00 3.83  ? 404 SER B OG  1 
ATOM 4574 N N   . VAL B 1 405 ? 119.653 149.357 156.577 1.00 1.33  ? 405 VAL B N   1 
ATOM 4575 C CA  . VAL B 1 405 ? 120.227 149.405 157.918 1.00 1.68  ? 405 VAL B CA  1 
ATOM 4576 C C   . VAL B 1 405 ? 120.934 150.733 158.169 1.00 0.39  ? 405 VAL B C   1 
ATOM 4577 O O   . VAL B 1 405 ? 120.997 151.203 159.310 1.00 6.15  ? 405 VAL B O   1 
ATOM 4578 C CB  . VAL B 1 405 ? 121.165 148.196 158.120 1.00 2.58  ? 405 VAL B CB  1 
ATOM 4579 C CG1 . VAL B 1 405 ? 122.144 148.096 156.972 1.00 1.68  ? 405 VAL B CG1 1 
ATOM 4580 C CG2 . VAL B 1 405 ? 121.896 148.277 159.454 1.00 0.99  ? 405 VAL B CG2 1 
ATOM 4581 N N   . ILE B 1 406 ? 121.456 151.371 157.120 1.00 1.34  ? 406 ILE B N   1 
ATOM 4582 C CA  . ILE B 1 406 ? 122.103 152.670 157.288 1.00 2.60  ? 406 ILE B CA  1 
ATOM 4583 C C   . ILE B 1 406 ? 121.088 153.736 157.700 1.00 2.65  ? 406 ILE B C   1 
ATOM 4584 O O   . ILE B 1 406 ? 121.374 154.587 158.551 1.00 7.28  ? 406 ILE B O   1 
ATOM 4585 C CB  . ILE B 1 406 ? 122.856 153.058 156.003 1.00 3.71  ? 406 ILE B CB  1 
ATOM 4586 C CG1 . ILE B 1 406 ? 123.964 152.041 155.717 1.00 0.00  ? 406 ILE B CG1 1 
ATOM 4587 C CG2 . ILE B 1 406 ? 123.433 154.458 156.116 1.00 1.59  ? 406 ILE B CG2 1 
ATOM 4588 C CD1 . ILE B 1 406 ? 124.647 152.232 154.385 1.00 1.70  ? 406 ILE B CD1 1 
ATOM 4589 N N   . LEU B 1 407 ? 119.891 153.712 157.106 1.00 1.70  ? 407 LEU B N   1 
ATOM 4590 C CA  . LEU B 1 407 ? 118.861 154.678 157.484 1.00 0.63  ? 407 LEU B CA  1 
ATOM 4591 C C   . LEU B 1 407 ? 118.387 154.454 158.916 1.00 5.41  ? 407 LEU B C   1 
ATOM 4592 O O   . LEU B 1 407 ? 118.145 155.419 159.656 1.00 4.92  ? 407 LEU B O   1 
ATOM 4593 C CB  . LEU B 1 407 ? 117.687 154.605 156.508 1.00 3.00  ? 407 LEU B CB  1 
ATOM 4594 C CG  . LEU B 1 407 ? 118.029 154.724 155.020 1.00 3.63  ? 407 LEU B CG  1 
ATOM 4595 C CD1 . LEU B 1 407 ? 116.763 154.795 154.178 1.00 1.70  ? 407 LEU B CD1 1 
ATOM 4596 C CD2 . LEU B 1 407 ? 118.914 155.935 154.764 1.00 3.39  ? 407 LEU B CD2 1 
ATOM 4597 N N   . MET B 1 408 ? 118.246 153.190 159.326 1.00 1.50  ? 408 MET B N   1 
ATOM 4598 C CA  . MET B 1 408 ? 117.908 152.899 160.715 1.00 2.04  ? 408 MET B CA  1 
ATOM 4599 C C   . MET B 1 408 ? 119.012 153.357 161.654 1.00 3.64  ? 408 MET B C   1 
ATOM 4600 O O   . MET B 1 408 ? 118.736 153.857 162.748 1.00 4.86  ? 408 MET B O   1 
ATOM 4601 C CB  . MET B 1 408 ? 117.637 151.406 160.899 1.00 3.13  ? 408 MET B CB  1 
ATOM 4602 C CG  . MET B 1 408 ? 116.744 150.803 159.840 1.00 3.09  ? 408 MET B CG  1 
ATOM 4603 S SD  . MET B 1 408 ? 115.065 151.431 159.993 1.00 9.75  ? 408 MET B SD  1 
ATOM 4604 C CE  . MET B 1 408 ? 114.521 150.588 161.474 1.00 1.03  ? 408 MET B CE  1 
ATOM 4605 N N   . ASP B 1 409 ? 120.271 153.183 161.249 1.00 1.94  ? 409 ASP B N   1 
ATOM 4606 C CA  . ASP B 1 409 ? 121.383 153.657 162.064 1.00 3.10  ? 409 ASP B CA  1 
ATOM 4607 C C   . ASP B 1 409 ? 121.353 155.172 162.199 1.00 3.32  ? 409 ASP B C   1 
ATOM 4608 O O   . ASP B 1 409 ? 121.648 155.711 163.268 1.00 9.11  ? 409 ASP B O   1 
ATOM 4609 C CB  . ASP B 1 409 ? 122.710 153.190 161.465 1.00 4.82  ? 409 ASP B CB  1 
ATOM 4610 C CG  . ASP B 1 409 ? 123.003 151.733 161.765 1.00 4.40  ? 409 ASP B CG  1 
ATOM 4611 O OD1 . ASP B 1 409 ? 122.305 151.149 162.619 1.00 4.96  ? 409 ASP B OD1 1 
ATOM 4612 O OD2 . ASP B 1 409 ? 123.925 151.169 161.141 1.00 5.21  ? 409 ASP B OD2 1 
ATOM 4613 N N   . LEU B 1 410 ? 120.995 155.875 161.124 1.00 6.85  ? 410 LEU B N   1 
ATOM 4614 C CA  . LEU B 1 410 ? 120.862 157.328 161.198 1.00 7.25  ? 410 LEU B CA  1 
ATOM 4615 C C   . LEU B 1 410 ? 119.735 157.740 162.141 1.00 3.44  ? 410 LEU B C   1 
ATOM 4616 O O   . LEU B 1 410 ? 119.894 158.670 162.941 1.00 7.40  ? 410 LEU B O   1 
ATOM 4617 C CB  . LEU B 1 410 ? 120.631 157.901 159.801 1.00 4.76  ? 410 LEU B CB  1 
ATOM 4618 C CG  . LEU B 1 410 ? 120.782 159.415 159.648 1.00 6.97  ? 410 LEU B CG  1 
ATOM 4619 C CD1 . LEU B 1 410 ? 121.645 159.744 158.444 1.00 5.37  ? 410 LEU B CD1 1 
ATOM 4620 C CD2 . LEU B 1 410 ? 119.420 160.082 159.530 1.00 5.46  ? 410 LEU B CD2 1 
ATOM 4621 N N   . GLU B 1 411 ? 118.586 157.065 162.056 1.00 2.75  ? 411 GLU B N   1 
ATOM 4622 C CA  . GLU B 1 411 ? 117.481 157.373 162.962 1.00 3.18  ? 411 GLU B CA  1 
ATOM 4623 C C   . GLU B 1 411 ? 117.864 157.096 164.413 1.00 8.27  ? 411 GLU B C   1 
ATOM 4624 O O   . GLU B 1 411 ? 117.533 157.878 165.316 1.00 8.07  ? 411 GLU B O   1 
ATOM 4625 C CB  . GLU B 1 411 ? 116.241 156.570 162.567 1.00 2.57  ? 411 GLU B CB  1 
ATOM 4626 C CG  . GLU B 1 411 ? 114.930 157.176 163.037 1.00 2.68  ? 411 GLU B CG  1 
ATOM 4627 C CD  . GLU B 1 411 ? 114.317 156.416 164.199 1.00 6.77  ? 411 GLU B CD  1 
ATOM 4628 O OE1 . GLU B 1 411 ? 115.024 155.593 164.818 1.00 11.75 ? 411 GLU B OE1 1 
ATOM 4629 O OE2 . GLU B 1 411 ? 113.126 156.642 164.494 1.00 7.47  ? 411 GLU B OE2 1 
ATOM 4630 N N   . TYR B 1 412 ? 118.565 155.987 164.653 1.00 6.09  ? 412 TYR B N   1 
ATOM 4631 C CA  . TYR B 1 412 ? 119.048 155.666 165.991 1.00 10.16 ? 412 TYR B CA  1 
ATOM 4632 C C   . TYR B 1 412 ? 120.047 156.708 166.477 1.00 8.23  ? 412 TYR B C   1 
ATOM 4633 O O   . TYR B 1 412 ? 120.048 157.076 167.654 1.00 7.96  ? 412 TYR B O   1 
ATOM 4634 C CB  . TYR B 1 412 ? 119.669 154.265 165.991 1.00 4.83  ? 412 TYR B CB  1 
ATOM 4635 C CG  . TYR B 1 412 ? 120.310 153.853 167.296 1.00 4.69  ? 412 TYR B CG  1 
ATOM 4636 C CD1 . TYR B 1 412 ? 119.564 153.245 168.297 1.00 6.92  ? 412 TYR B CD1 1 
ATOM 4637 C CD2 . TYR B 1 412 ? 121.664 154.063 167.525 1.00 6.95  ? 412 TYR B CD2 1 
ATOM 4638 C CE1 . TYR B 1 412 ? 120.147 152.864 169.490 1.00 5.51  ? 412 TYR B CE1 1 
ATOM 4639 C CE2 . TYR B 1 412 ? 122.254 153.687 168.714 1.00 5.67  ? 412 TYR B CE2 1 
ATOM 4640 C CZ  . TYR B 1 412 ? 121.492 153.088 169.693 1.00 7.06  ? 412 TYR B CZ  1 
ATOM 4641 O OH  . TYR B 1 412 ? 122.078 152.710 170.879 1.00 9.29  ? 412 TYR B OH  1 
ATOM 4642 N N   . MET B 1 413 ? 120.916 157.184 165.582 1.00 6.01  ? 413 MET B N   1 
ATOM 4643 C CA  . MET B 1 413 ? 121.873 158.225 165.933 1.00 3.92  ? 413 MET B CA  1 
ATOM 4644 C C   . MET B 1 413 ? 121.168 159.510 166.339 1.00 6.78  ? 413 MET B C   1 
ATOM 4645 O O   . MET B 1 413 ? 121.536 160.134 167.341 1.00 10.99 ? 413 MET B O   1 
ATOM 4646 C CB  . MET B 1 413 ? 122.810 158.475 164.749 1.00 4.14  ? 413 MET B CB  1 
ATOM 4647 C CG  . MET B 1 413 ? 124.022 159.335 165.052 1.00 9.90  ? 413 MET B CG  1 
ATOM 4648 S SD  . MET B 1 413 ? 125.366 159.026 163.887 1.00 24.25 ? 413 MET B SD  1 
ATOM 4649 C CE  . MET B 1 413 ? 126.272 160.566 163.980 1.00 4.34  ? 413 MET B CE  1 
ATOM 4650 N N   . ILE B 1 414 ? 120.148 159.911 165.582 1.00 8.27  ? 414 ILE B N   1 
ATOM 4651 C CA  . ILE B 1 414 ? 119.340 161.081 165.902 1.00 6.45  ? 414 ILE B CA  1 
ATOM 4652 C C   . ILE B 1 414 ? 118.637 160.926 167.243 1.00 7.35  ? 414 ILE B C   1 
ATOM 4653 O O   . ILE B 1 414 ? 118.613 161.872 168.039 1.00 9.55  ? 414 ILE B O   1 
ATOM 4654 C CB  . ILE B 1 414 ? 118.326 161.386 164.786 1.00 7.02  ? 414 ILE B CB  1 
ATOM 4655 C CG1 . ILE B 1 414 ? 119.047 161.606 163.454 1.00 8.03  ? 414 ILE B CG1 1 
ATOM 4656 C CG2 . ILE B 1 414 ? 117.477 162.597 165.148 1.00 8.65  ? 414 ILE B CG2 1 
ATOM 4657 C CD1 . ILE B 1 414 ? 118.208 162.299 162.405 1.00 8.45  ? 414 ILE B CD1 1 
ATOM 4658 N N   . CYS B 1 415 ? 118.066 159.755 167.518 1.00 8.61  ? 415 CYS B N   1 
ATOM 4659 C CA  . CYS B 1 415 ? 117.428 159.485 168.802 1.00 4.58  ? 415 CYS B CA  1 
ATOM 4660 C C   . CYS B 1 415 ? 118.412 159.504 169.967 1.00 9.17  ? 415 CYS B C   1 
ATOM 4661 O O   . CYS B 1 415 ? 118.101 160.039 171.034 1.00 10.96 ? 415 CYS B O   1 
ATOM 4662 C CB  . CYS B 1 415 ? 116.708 158.132 168.756 1.00 5.02  ? 415 CYS B CB  1 
ATOM 4663 S SG  . CYS B 1 415 ? 115.188 158.059 169.728 1.00 17.69 ? 415 CYS B SG  1 
ATOM 4664 N N   . PHE B 1 416 ? 119.599 158.924 169.781 1.00 10.55 ? 416 PHE B N   1 
ATOM 4665 C CA  . PHE B 1 416 ? 120.548 158.777 170.878 1.00 7.72  ? 416 PHE B CA  1 
ATOM 4666 C C   . PHE B 1 416 ? 121.226 160.103 171.206 1.00 8.09  ? 416 PHE B C   1 
ATOM 4667 O O   . PHE B 1 416 ? 121.397 160.455 172.378 1.00 9.71  ? 416 PHE B O   1 
ATOM 4668 C CB  . PHE B 1 416 ? 121.582 157.706 170.521 1.00 6.92  ? 416 PHE B CB  1 
ATOM 4669 C CG  . PHE B 1 416 ? 122.782 157.687 171.426 1.00 7.88  ? 416 PHE B CG  1 
ATOM 4670 C CD1 . PHE B 1 416 ? 122.667 157.265 172.740 1.00 7.10  ? 416 PHE B CD1 1 
ATOM 4671 C CD2 . PHE B 1 416 ? 124.024 158.087 170.964 1.00 10.68 ? 416 PHE B CD2 1 
ATOM 4672 C CE1 . PHE B 1 416 ? 123.768 157.243 173.574 1.00 7.32  ? 416 PHE B CE1 1 
ATOM 4673 C CE2 . PHE B 1 416 ? 125.127 158.069 171.794 1.00 9.71  ? 416 PHE B CE2 1 
ATOM 4674 C CZ  . PHE B 1 416 ? 125.000 157.646 173.099 1.00 5.51  ? 416 PHE B CZ  1 
ATOM 4675 N N   . TYR B 1 417 ? 121.622 160.860 170.176 1.00 8.49  ? 417 TYR B N   1 
ATOM 4676 C CA  . TYR B 1 417 ? 122.310 162.124 170.418 1.00 10.64 ? 417 TYR B CA  1 
ATOM 4677 C C   . TYR B 1 417 ? 121.384 163.170 171.023 1.00 8.37  ? 417 TYR B C   1 
ATOM 4678 O O   . TYR B 1 417 ? 121.851 164.119 171.662 1.00 14.69 ? 417 TYR B O   1 
ATOM 4679 C CB  . TYR B 1 417 ? 122.920 162.657 169.120 1.00 8.76  ? 417 TYR B CB  1 
ATOM 4680 C CG  . TYR B 1 417 ? 124.347 162.215 168.876 1.00 9.89  ? 417 TYR B CG  1 
ATOM 4681 C CD1 . TYR B 1 417 ? 124.722 160.888 169.036 1.00 10.47 ? 417 TYR B CD1 1 
ATOM 4682 C CD2 . TYR B 1 417 ? 125.321 163.128 168.495 1.00 11.07 ? 417 TYR B CD2 1 
ATOM 4683 C CE1 . TYR B 1 417 ? 126.025 160.482 168.815 1.00 10.18 ? 417 TYR B CE1 1 
ATOM 4684 C CE2 . TYR B 1 417 ? 126.626 162.731 168.272 1.00 8.83  ? 417 TYR B CE2 1 
ATOM 4685 C CZ  . TYR B 1 417 ? 126.972 161.408 168.434 1.00 8.24  ? 417 TYR B CZ  1 
ATOM 4686 O OH  . TYR B 1 417 ? 128.271 161.009 168.213 1.00 10.83 ? 417 TYR B OH  1 
ATOM 4687 N N   . SER B 1 418 ? 120.074 163.024 170.828 1.00 9.37  ? 418 SER B N   1 
ATOM 4688 C CA  . SER B 1 418 ? 119.122 164.000 171.342 1.00 7.67  ? 418 SER B CA  1 
ATOM 4689 C C   . SER B 1 418 ? 118.684 163.657 172.761 1.00 10.66 ? 418 SER B C   1 
ATOM 4690 O O   . SER B 1 418 ? 118.819 164.480 173.672 1.00 14.43 ? 418 SER B O   1 
ATOM 4691 C CB  . SER B 1 418 ? 117.902 164.094 170.422 1.00 10.08 ? 418 SER B CB  1 
ATOM 4692 O OG  . SER B 1 418 ? 117.215 162.857 170.355 1.00 16.31 ? 418 SER B OG  1 
ATOM 4693 N N   . LEU B 1 419 ? 118.157 162.447 172.959 1.00 9.72  ? 419 LEU B N   1 
ATOM 4694 C CA  . LEU B 1 419 ? 117.610 162.080 174.262 1.00 10.89 ? 419 LEU B CA  1 
ATOM 4695 C C   . LEU B 1 419 ? 118.715 161.688 175.235 1.00 8.39  ? 419 LEU B C   1 
ATOM 4696 O O   . LEU B 1 419 ? 118.863 162.290 176.306 1.00 15.13 ? 419 LEU B O   1 
ATOM 4697 C CB  . LEU B 1 419 ? 116.599 160.942 174.104 1.00 8.24  ? 419 LEU B CB  1 
ATOM 4698 C CG  . LEU B 1 419 ? 115.335 161.227 173.288 1.00 8.11  ? 419 LEU B CG  1 
ATOM 4699 C CD1 . LEU B 1 419 ? 114.198 160.331 173.749 1.00 8.39  ? 419 LEU B CD1 1 
ATOM 4700 C CD2 . LEU B 1 419 ? 114.933 162.691 173.390 1.00 7.83  ? 419 LEU B CD2 1 
ATOM 4701 N N   . GLU B 1 420 ? 119.503 160.677 174.881 1.00 8.87  ? 420 GLU B N   1 
ATOM 4702 C CA  . GLU B 1 420 ? 120.561 160.188 175.755 1.00 10.46 ? 420 GLU B CA  1 
ATOM 4703 C C   . GLU B 1 420 ? 121.847 160.994 175.643 1.00 9.17  ? 420 GLU B C   1 
ATOM 4704 O O   . GLU B 1 420 ? 122.814 160.678 176.346 1.00 10.36 ? 420 GLU B O   1 
ATOM 4705 C CB  . GLU B 1 420 ? 120.850 158.715 175.453 1.00 8.72  ? 420 GLU B CB  1 
ATOM 4706 C CG  . GLU B 1 420 ? 119.777 157.758 175.943 1.00 8.62  ? 420 GLU B CG  1 
ATOM 4707 C CD  . GLU B 1 420 ? 119.970 156.351 175.418 1.00 12.31 ? 420 GLU B CD  1 
ATOM 4708 O OE1 . GLU B 1 420 ? 119.049 155.830 174.754 1.00 14.58 ? 420 GLU B OE1 1 
ATOM 4709 O OE2 . GLU B 1 420 ? 121.044 155.765 175.667 1.00 11.66 ? 420 GLU B OE2 1 
ATOM 4710 N N   . LEU B 1 421 ? 121.884 162.003 174.768 1.00 9.95  ? 421 LEU B N   1 
ATOM 4711 C CA  . LEU B 1 421 ? 123.039 162.876 174.571 1.00 7.68  ? 421 LEU B CA  1 
ATOM 4712 C C   . LEU B 1 421 ? 124.501 163.066 174.183 1.00 10.96 ? 421 LEU B C   1 
ATOM 4713 O O   . LEU B 1 421 ? 125.163 164.000 174.646 1.00 9.81  ? 421 LEU B O   1 
ATOM 4714 C CB  . LEU B 1 421 ? 123.435 163.568 175.881 1.00 7.56  ? 421 LEU B CB  1 
ATOM 4715 C CG  . LEU B 1 421 ? 122.384 164.436 176.583 1.00 10.40 ? 421 LEU B CG  1 
ATOM 4716 C CD1 . LEU B 1 421 ? 123.054 165.490 177.453 1.00 8.15  ? 421 LEU B CD1 1 
ATOM 4717 C CD2 . LEU B 1 421 ? 121.450 165.097 175.581 1.00 9.34  ? 421 LEU B CD2 1 
ATOM 4718 N N   . LYS B 1 422 ? 125.015 162.178 173.340 1.00 13.54 ? 422 LYS B N   1 
ATOM 4719 C CA  . LYS B 1 422 ? 126.415 162.224 172.940 1.00 9.14  ? 422 LYS B CA  1 
ATOM 4720 C C   . LYS B 1 422 ? 127.524 161.977 173.956 1.00 11.38 ? 422 LYS B C   1 
ATOM 4721 O O   . LYS B 1 422 ? 127.830 160.832 174.289 1.00 19.90 ? 422 LYS B O   1 
ATOM 4722 C CB  . LYS B 1 422 ? 126.921 163.094 171.804 1.00 8.56  ? 422 LYS B CB  1 
ATOM 4723 N N   . TYR B 1 443 ? 111.585 153.004 172.222 1.00 10.21 ? 443 TYR B N   1 
ATOM 4724 C CA  . TYR B 1 443 ? 111.012 151.670 172.363 1.00 8.85  ? 443 TYR B CA  1 
ATOM 4725 C C   . TYR B 1 443 ? 110.630 151.113 170.996 1.00 12.95 ? 443 TYR B C   1 
ATOM 4726 O O   . TYR B 1 443 ? 111.491 150.864 170.153 1.00 16.38 ? 443 TYR B O   1 
ATOM 4727 C CB  . TYR B 1 443 ? 109.790 151.701 173.286 1.00 7.19  ? 443 TYR B CB  1 
ATOM 4728 C CG  . TYR B 1 443 ? 110.122 151.843 174.757 1.00 12.49 ? 443 TYR B CG  1 
ATOM 4729 C CD1 . TYR B 1 443 ? 111.422 152.089 175.179 1.00 11.26 ? 443 TYR B CD1 1 
ATOM 4730 C CD2 . TYR B 1 443 ? 109.131 151.733 175.724 1.00 8.59  ? 443 TYR B CD2 1 
ATOM 4731 C CE1 . TYR B 1 443 ? 111.727 152.220 176.520 1.00 10.08 ? 443 TYR B CE1 1 
ATOM 4732 C CE2 . TYR B 1 443 ? 109.426 151.863 177.067 1.00 8.42  ? 443 TYR B CE2 1 
ATOM 4733 C CZ  . TYR B 1 443 ? 110.725 152.106 177.460 1.00 12.84 ? 443 TYR B CZ  1 
ATOM 4734 O OH  . TYR B 1 443 ? 111.026 152.235 178.796 1.00 15.00 ? 443 TYR B OH  1 
ATOM 4735 N N   . THR B 1 444 ? 109.333 150.914 170.785 1.00 8.30  ? 444 THR B N   1 
ATOM 4736 C CA  . THR B 1 444 ? 108.788 150.525 169.491 1.00 5.93  ? 444 THR B CA  1 
ATOM 4737 C C   . THR B 1 444 ? 107.774 151.578 169.067 1.00 10.06 ? 444 THR B C   1 
ATOM 4738 O O   . THR B 1 444 ? 106.670 151.638 169.618 1.00 10.08 ? 444 THR B O   1 
ATOM 4739 C CB  . THR B 1 444 ? 108.137 149.143 169.553 1.00 9.53  ? 444 THR B CB  1 
ATOM 4740 O OG1 . THR B 1 444 ? 109.053 148.204 170.129 1.00 15.89 ? 444 THR B OG1 1 
ATOM 4741 C CG2 . THR B 1 444 ? 107.751 148.673 168.159 1.00 6.23  ? 444 THR B CG2 1 
ATOM 4742 N N   . TYR B 1 445 ? 108.151 152.404 168.094 1.00 9.06  ? 445 TYR B N   1 
ATOM 4743 C CA  . TYR B 1 445 ? 107.317 153.507 167.640 1.00 7.05  ? 445 TYR B CA  1 
ATOM 4744 C C   . TYR B 1 445 ? 107.151 153.439 166.129 1.00 8.48  ? 445 TYR B C   1 
ATOM 4745 O O   . TYR B 1 445 ? 107.945 152.807 165.426 1.00 5.91  ? 445 TYR B O   1 
ATOM 4746 C CB  . TYR B 1 445 ? 107.898 154.877 168.045 1.00 7.94  ? 445 TYR B CB  1 
ATOM 4747 C CG  . TYR B 1 445 ? 109.412 154.957 168.059 1.00 6.80  ? 445 TYR B CG  1 
ATOM 4748 C CD1 . TYR B 1 445 ? 110.148 154.446 169.122 1.00 3.00  ? 445 TYR B CD1 1 
ATOM 4749 C CD2 . TYR B 1 445 ? 110.103 155.554 167.014 1.00 4.13  ? 445 TYR B CD2 1 
ATOM 4750 C CE1 . TYR B 1 445 ? 111.526 154.518 169.137 1.00 5.87  ? 445 TYR B CE1 1 
ATOM 4751 C CE2 . TYR B 1 445 ? 111.483 155.632 167.021 1.00 4.06  ? 445 TYR B CE2 1 
ATOM 4752 C CZ  . TYR B 1 445 ? 112.189 155.114 168.086 1.00 7.42  ? 445 TYR B CZ  1 
ATOM 4753 O OH  . TYR B 1 445 ? 113.563 155.190 168.098 1.00 6.97  ? 445 TYR B OH  1 
ATOM 4754 N N   . GLY B 1 446 ? 106.099 154.096 165.640 1.00 6.04  ? 446 GLY B N   1 
ATOM 4755 C CA  . GLY B 1 446 ? 105.772 154.062 164.226 1.00 6.31  ? 446 GLY B CA  1 
ATOM 4756 C C   . GLY B 1 446 ? 106.811 154.693 163.324 1.00 7.18  ? 446 GLY B C   1 
ATOM 4757 O O   . GLY B 1 446 ? 106.983 154.237 162.190 1.00 10.08 ? 446 GLY B O   1 
ATOM 4758 N N   . VAL B 1 447 ? 107.506 155.729 163.801 1.00 7.85  ? 447 VAL B N   1 
ATOM 4759 C CA  . VAL B 1 447 ? 108.460 156.448 162.957 1.00 8.25  ? 447 VAL B CA  1 
ATOM 4760 C C   . VAL B 1 447 ? 109.579 155.520 162.497 1.00 5.59  ? 447 VAL B C   1 
ATOM 4761 O O   . VAL B 1 447 ? 109.989 155.546 161.327 1.00 9.57  ? 447 VAL B O   1 
ATOM 4762 C CB  . VAL B 1 447 ? 109.010 157.677 163.706 1.00 4.95  ? 447 VAL B CB  1 
ATOM 4763 C CG1 . VAL B 1 447 ? 110.352 158.103 163.135 1.00 2.75  ? 447 VAL B CG1 1 
ATOM 4764 C CG2 . VAL B 1 447 ? 108.014 158.824 163.644 1.00 8.37  ? 447 VAL B CG2 1 
ATOM 4765 N N   . ARG B 1 448 ? 110.089 154.686 163.406 1.00 2.56  ? 448 ARG B N   1 
ATOM 4766 C CA  . ARG B 1 448 ? 111.155 153.757 163.044 1.00 6.57  ? 448 ARG B CA  1 
ATOM 4767 C C   . ARG B 1 448 ? 110.690 152.770 161.980 1.00 4.92  ? 448 ARG B C   1 
ATOM 4768 O O   . ARG B 1 448 ? 111.440 152.446 161.051 1.00 7.81  ? 448 ARG B O   1 
ATOM 4769 C CB  . ARG B 1 448 ? 111.649 153.019 164.288 1.00 5.15  ? 448 ARG B CB  1 
ATOM 4770 C CG  . ARG B 1 448 ? 113.090 152.555 164.193 1.00 4.62  ? 448 ARG B CG  1 
ATOM 4771 C CD  . ARG B 1 448 ? 113.680 152.256 165.569 1.00 6.18  ? 448 ARG B CD  1 
ATOM 4772 N NE  . ARG B 1 448 ? 114.906 151.461 165.526 1.00 11.83 ? 448 ARG B NE  1 
ATOM 4773 C CZ  . ARG B 1 448 ? 115.977 151.721 164.784 1.00 8.15  ? 448 ARG B CZ  1 
ATOM 4774 N NH1 . ARG B 1 448 ? 116.082 152.830 164.070 1.00 6.05  ? 448 ARG B NH1 1 
ATOM 4775 N NH2 . ARG B 1 448 ? 116.985 150.854 164.780 1.00 5.70  ? 448 ARG B NH2 1 
ATOM 4776 N N   . ALA B 1 449 ? 109.452 152.283 162.097 1.00 4.78  ? 449 ALA B N   1 
ATOM 4777 C CA  . ALA B 1 449 ? 108.902 151.393 161.080 1.00 3.20  ? 449 ALA B CA  1 
ATOM 4778 C C   . ALA B 1 449 ? 108.774 152.090 159.729 1.00 1.26  ? 449 ALA B C   1 
ATOM 4779 O O   . ALA B 1 449 ? 109.032 151.473 158.688 1.00 4.19  ? 449 ALA B O   1 
ATOM 4780 C CB  . ALA B 1 449 ? 107.547 150.852 161.536 1.00 4.29  ? 449 ALA B CB  1 
ATOM 4781 N N   . ILE B 1 450 ? 108.381 153.366 159.724 1.00 3.57  ? 450 ILE B N   1 
ATOM 4782 C CA  . ILE B 1 450 ? 108.304 154.121 158.476 1.00 3.98  ? 450 ILE B CA  1 
ATOM 4783 C C   . ILE B 1 450 ? 109.683 154.244 157.838 1.00 4.36  ? 450 ILE B C   1 
ATOM 4784 O O   . ILE B 1 450 ? 109.844 154.063 156.622 1.00 1.62  ? 450 ILE B O   1 
ATOM 4785 C CB  . ILE B 1 450 ? 107.672 155.502 158.726 1.00 4.42  ? 450 ILE B CB  1 
ATOM 4786 C CG1 . ILE B 1 450 ? 106.287 155.349 159.360 1.00 7.22  ? 450 ILE B CG1 1 
ATOM 4787 C CG2 . ILE B 1 450 ? 107.597 156.299 157.433 1.00 2.50  ? 450 ILE B CG2 1 
ATOM 4788 C CD1 . ILE B 1 450 ? 105.447 156.608 159.327 1.00 8.20  ? 450 ILE B CD1 1 
ATOM 4789 N N   . VAL B 1 451 ? 110.698 154.563 158.647 1.00 1.11  ? 451 VAL B N   1 
ATOM 4790 C CA  . VAL B 1 451 ? 112.057 154.657 158.120 1.00 0.96  ? 451 VAL B CA  1 
ATOM 4791 C C   . VAL B 1 451 ? 112.497 153.313 157.553 1.00 1.59  ? 451 VAL B C   1 
ATOM 4792 O O   . VAL B 1 451 ? 113.151 153.247 156.505 1.00 4.09  ? 451 VAL B O   1 
ATOM 4793 C CB  . VAL B 1 451 ? 113.025 155.162 159.207 1.00 2.89  ? 451 VAL B CB  1 
ATOM 4794 C CG1 . VAL B 1 451 ? 114.464 155.095 158.714 1.00 0.96  ? 451 VAL B CG1 1 
ATOM 4795 C CG2 . VAL B 1 451 ? 112.668 156.580 159.623 1.00 0.00  ? 451 VAL B CG2 1 
ATOM 4796 N N   . GLN B 1 452 ? 112.136 152.222 158.231 1.00 0.00  ? 452 GLN B N   1 
ATOM 4797 C CA  . GLN B 1 452 ? 112.482 150.891 157.741 1.00 0.00  ? 452 GLN B CA  1 
ATOM 4798 C C   . GLN B 1 452 ? 111.799 150.592 156.411 1.00 0.09  ? 452 GLN B C   1 
ATOM 4799 O O   . GLN B 1 452 ? 112.378 149.931 155.541 1.00 1.72  ? 452 GLN B O   1 
ATOM 4800 C CB  . GLN B 1 452 ? 112.114 149.838 158.787 1.00 0.00  ? 452 GLN B CB  1 
ATOM 4801 C CG  . GLN B 1 452 ? 112.345 148.410 158.339 1.00 0.37  ? 452 GLN B CG  1 
ATOM 4802 C CD  . GLN B 1 452 ? 113.817 148.065 158.238 1.00 2.27  ? 452 GLN B CD  1 
ATOM 4803 O OE1 . GLN B 1 452 ? 114.398 148.088 157.154 1.00 2.90  ? 452 GLN B OE1 1 
ATOM 4804 N NE2 . GLN B 1 452 ? 114.427 147.741 159.370 1.00 2.44  ? 452 GLN B NE2 1 
ATOM 4805 N N   . CYS B 1 453 ? 110.569 151.067 156.236 1.00 0.33  ? 453 CYS B N   1 
ATOM 4806 C CA  . CYS B 1 453 ? 109.823 150.803 155.012 1.00 1.08  ? 453 CYS B CA  1 
ATOM 4807 C C   . CYS B 1 453 ? 110.130 151.784 153.884 1.00 2.48  ? 453 CYS B C   1 
ATOM 4808 O O   . CYS B 1 453 ? 109.643 151.579 152.768 1.00 0.00  ? 453 CYS B O   1 
ATOM 4809 C CB  . CYS B 1 453 ? 108.321 150.819 155.306 1.00 0.00  ? 453 CYS B CB  1 
ATOM 4810 S SG  . CYS B 1 453 ? 107.753 149.446 156.323 1.00 10.49 ? 453 CYS B SG  1 
ATOM 4811 N N   . ILE B 1 454 ? 110.908 152.840 154.150 1.00 0.00  ? 454 ILE B N   1 
ATOM 4812 C CA  . ILE B 1 454 ? 111.151 153.871 153.132 1.00 1.82  ? 454 ILE B CA  1 
ATOM 4813 C C   . ILE B 1 454 ? 111.711 153.320 151.814 1.00 0.28  ? 454 ILE B C   1 
ATOM 4814 O O   . ILE B 1 454 ? 111.179 153.675 150.753 1.00 0.00  ? 454 ILE B O   1 
ATOM 4815 C CB  . ILE B 1 454 ? 112.017 154.999 153.721 1.00 1.91  ? 454 ILE B CB  1 
ATOM 4816 C CG1 . ILE B 1 454 ? 111.134 156.083 154.341 1.00 0.86  ? 454 ILE B CG1 1 
ATOM 4817 C CG2 . ILE B 1 454 ? 112.921 155.613 152.661 1.00 1.00  ? 454 ILE B CG2 1 
ATOM 4818 C CD1 . ILE B 1 454 ? 111.873 157.003 155.287 1.00 1.59  ? 454 ILE B CD1 1 
ATOM 4819 N N   . PRO B 1 455 ? 112.774 152.498 151.797 1.00 0.00  ? 455 PRO B N   1 
ATOM 4820 C CA  . PRO B 1 455 ? 113.265 151.998 150.494 1.00 0.00  ? 455 PRO B CA  1 
ATOM 4821 C C   . PRO B 1 455 ? 112.246 151.150 149.750 1.00 0.71  ? 455 PRO B C   1 
ATOM 4822 O O   . PRO B 1 455 ? 112.118 151.251 148.517 1.00 0.00  ? 455 PRO B O   1 
ATOM 4823 C CB  . PRO B 1 455 ? 114.512 151.187 150.874 1.00 0.00  ? 455 PRO B CB  1 
ATOM 4824 C CG  . PRO B 1 455 ? 114.912 151.701 152.214 1.00 0.00  ? 455 PRO B CG  1 
ATOM 4825 C CD  . PRO B 1 455 ? 113.635 152.044 152.904 1.00 0.00  ? 455 PRO B CD  1 
ATOM 4826 N N   . ALA B 1 456 ? 111.504 150.318 150.483 1.00 0.00  ? 456 ALA B N   1 
ATOM 4827 C CA  . ALA B 1 456 ? 110.423 149.558 149.872 1.00 0.00  ? 456 ALA B CA  1 
ATOM 4828 C C   . ALA B 1 456 ? 109.354 150.488 149.320 1.00 0.00  ? 456 ALA B C   1 
ATOM 4829 O O   . ALA B 1 456 ? 108.777 150.218 148.263 1.00 2.49  ? 456 ALA B O   1 
ATOM 4830 C CB  . ALA B 1 456 ? 109.824 148.587 150.885 1.00 0.00  ? 456 ALA B CB  1 
ATOM 4831 N N   . TRP B 1 457 ? 109.084 151.593 150.019 1.00 0.00  ? 457 TRP B N   1 
ATOM 4832 C CA  . TRP B 1 457 ? 108.137 152.583 149.517 1.00 0.00  ? 457 TRP B CA  1 
ATOM 4833 C C   . TRP B 1 457 ? 108.622 153.194 148.210 1.00 1.48  ? 457 TRP B C   1 
ATOM 4834 O O   . TRP B 1 457 ? 107.835 153.390 147.276 1.00 1.47  ? 457 TRP B O   1 
ATOM 4835 C CB  . TRP B 1 457 ? 107.911 153.667 150.571 1.00 0.00  ? 457 TRP B CB  1 
ATOM 4836 C CG  . TRP B 1 457 ? 107.297 154.916 150.028 1.00 0.33  ? 457 TRP B CG  1 
ATOM 4837 C CD1 . TRP B 1 457 ? 107.943 156.069 149.694 1.00 1.57  ? 457 TRP B CD1 1 
ATOM 4838 C CD2 . TRP B 1 457 ? 105.910 155.139 149.752 1.00 2.34  ? 457 TRP B CD2 1 
ATOM 4839 N NE1 . TRP B 1 457 ? 107.045 156.996 149.227 1.00 0.00  ? 457 TRP B NE1 1 
ATOM 4840 C CE2 . TRP B 1 457 ? 105.789 156.450 149.254 1.00 0.20  ? 457 TRP B CE2 1 
ATOM 4841 C CE3 . TRP B 1 457 ? 104.758 154.356 149.877 1.00 0.00  ? 457 TRP B CE3 1 
ATOM 4842 C CZ2 . TRP B 1 457 ? 104.563 156.997 148.881 1.00 4.54  ? 457 TRP B CZ2 1 
ATOM 4843 C CZ3 . TRP B 1 457 ? 103.542 154.901 149.508 1.00 1.20  ? 457 TRP B CZ3 1 
ATOM 4844 C CH2 . TRP B 1 457 ? 103.455 156.208 149.015 1.00 4.22  ? 457 TRP B CH2 1 
ATOM 4845 N N   . LEU B 1 458 ? 109.916 153.506 148.127 1.00 0.00  ? 458 LEU B N   1 
ATOM 4846 C CA  . LEU B 1 458 ? 110.463 154.070 146.898 1.00 0.00  ? 458 LEU B CA  1 
ATOM 4847 C C   . LEU B 1 458 ? 110.302 153.097 145.733 1.00 0.00  ? 458 LEU B C   1 
ATOM 4848 O O   . LEU B 1 458 ? 109.826 153.475 144.655 1.00 0.00  ? 458 LEU B O   1 
ATOM 4849 C CB  . LEU B 1 458 ? 111.932 154.444 147.104 1.00 0.00  ? 458 LEU B CB  1 
ATOM 4850 C CG  . LEU B 1 458 ? 112.208 155.503 148.178 1.00 2.86  ? 458 LEU B CG  1 
ATOM 4851 C CD1 . LEU B 1 458 ? 113.697 155.626 148.460 1.00 0.33  ? 458 LEU B CD1 1 
ATOM 4852 C CD2 . LEU B 1 458 ? 111.621 156.853 147.787 1.00 0.00  ? 458 LEU B CD2 1 
ATOM 4853 N N   . ARG B 1 459 ? 110.665 151.828 145.946 1.00 2.83  ? 459 ARG B N   1 
ATOM 4854 C CA  . ARG B 1 459 ? 110.514 150.833 144.883 1.00 1.76  ? 459 ARG B CA  1 
ATOM 4855 C C   . ARG B 1 459 ? 109.045 150.636 144.508 1.00 0.00  ? 459 ARG B C   1 
ATOM 4856 O O   . ARG B 1 459 ? 108.708 150.511 143.324 1.00 0.00  ? 459 ARG B O   1 
ATOM 4857 C CB  . ARG B 1 459 ? 111.142 149.502 145.305 1.00 0.00  ? 459 ARG B CB  1 
ATOM 4858 C CG  . ARG B 1 459 ? 112.648 149.384 145.057 1.00 0.00  ? 459 ARG B CG  1 
ATOM 4859 C CD  . ARG B 1 459 ? 113.026 149.566 143.588 1.00 0.00  ? 459 ARG B CD  1 
ATOM 4860 N NE  . ARG B 1 459 ? 112.564 148.473 142.742 1.00 0.00  ? 459 ARG B NE  1 
ATOM 4861 C CZ  . ARG B 1 459 ? 111.846 148.632 141.638 1.00 0.00  ? 459 ARG B CZ  1 
ATOM 4862 N NH1 . ARG B 1 459 ? 111.482 149.832 141.218 1.00 0.00  ? 459 ARG B NH1 1 
ATOM 4863 N NH2 . ARG B 1 459 ? 111.488 147.561 140.937 1.00 0.00  ? 459 ARG B NH2 1 
ATOM 4864 N N   . PHE B 1 460 ? 108.158 150.614 145.507 1.00 0.00  ? 460 PHE B N   1 
ATOM 4865 C CA  . PHE B 1 460 ? 106.731 150.412 145.271 1.00 2.17  ? 460 PHE B CA  1 
ATOM 4866 C C   . PHE B 1 460 ? 106.137 151.541 144.434 1.00 0.00  ? 460 PHE B C   1 
ATOM 4867 O O   . PHE B 1 460 ? 105.389 151.298 143.477 1.00 0.00  ? 460 PHE B O   1 
ATOM 4868 C CB  . PHE B 1 460 ? 106.018 150.291 146.623 1.00 0.58  ? 460 PHE B CB  1 
ATOM 4869 C CG  . PHE B 1 460 ? 104.518 150.283 146.540 1.00 0.29  ? 460 PHE B CG  1 
ATOM 4870 C CD1 . PHE B 1 460 ? 103.827 149.094 146.384 1.00 0.08  ? 460 PHE B CD1 1 
ATOM 4871 C CD2 . PHE B 1 460 ? 103.795 151.460 146.661 1.00 0.09  ? 460 PHE B CD2 1 
ATOM 4872 C CE1 . PHE B 1 460 ? 102.449 149.080 146.322 1.00 0.00  ? 460 PHE B CE1 1 
ATOM 4873 C CE2 . PHE B 1 460 ? 102.417 151.454 146.596 1.00 0.36  ? 460 PHE B CE2 1 
ATOM 4874 C CZ  . PHE B 1 460 ? 101.742 150.262 146.428 1.00 2.16  ? 460 PHE B CZ  1 
ATOM 4875 N N   . ILE B 1 461 ? 106.465 152.788 144.775 1.00 3.15  ? 461 ILE B N   1 
ATOM 4876 C CA  . ILE B 1 461 ? 105.894 153.904 144.030 1.00 0.00  ? 461 ILE B CA  1 
ATOM 4877 C C   . ILE B 1 461 ? 106.553 154.027 142.660 1.00 2.96  ? 461 ILE B C   1 
ATOM 4878 O O   . ILE B 1 461 ? 105.919 154.483 141.701 1.00 0.00  ? 461 ILE B O   1 
ATOM 4879 C CB  . ILE B 1 461 ? 105.981 155.205 144.854 1.00 2.70  ? 461 ILE B CB  1 
ATOM 4880 C CG1 . ILE B 1 461 ? 104.794 156.116 144.535 1.00 2.16  ? 461 ILE B CG1 1 
ATOM 4881 C CG2 . ILE B 1 461 ? 107.292 155.925 144.624 1.00 0.55  ? 461 ILE B CG2 1 
ATOM 4882 C CD1 . ILE B 1 461 ? 103.520 155.734 145.261 1.00 3.74  ? 461 ILE B CD1 1 
ATOM 4883 N N   . GLN B 1 462 ? 107.808 153.583 142.525 1.00 4.27  ? 462 GLN B N   1 
ATOM 4884 C CA  . GLN B 1 462 ? 108.407 153.482 141.198 1.00 0.91  ? 462 GLN B CA  1 
ATOM 4885 C C   . GLN B 1 462 ? 107.654 152.478 140.334 1.00 0.00  ? 462 GLN B C   1 
ATOM 4886 O O   . GLN B 1 462 ? 107.411 152.724 139.146 1.00 0.00  ? 462 GLN B O   1 
ATOM 4887 C CB  . GLN B 1 462 ? 109.880 153.088 141.312 1.00 0.00  ? 462 GLN B CB  1 
ATOM 4888 C CG  . GLN B 1 462 ? 110.845 154.255 141.441 1.00 0.21  ? 462 GLN B CG  1 
ATOM 4889 C CD  . GLN B 1 462 ? 112.296 153.811 141.440 1.00 0.12  ? 462 GLN B CD  1 
ATOM 4890 O OE1 . GLN B 1 462 ? 112.591 152.617 141.440 1.00 1.87  ? 462 GLN B OE1 1 
ATOM 4891 N NE2 . GLN B 1 462 ? 113.211 154.771 141.437 1.00 0.00  ? 462 GLN B NE2 1 
ATOM 4892 N N   . CYS B 1 463 ? 107.283 151.336 140.914 1.00 3.13  ? 463 CYS B N   1 
ATOM 4893 C CA  . CYS B 1 463 ? 106.516 150.341 140.170 1.00 0.70  ? 463 CYS B CA  1 
ATOM 4894 C C   . CYS B 1 463 ? 105.141 150.877 139.787 1.00 0.00  ? 463 CYS B C   1 
ATOM 4895 O O   . CYS B 1 463 ? 104.650 150.613 138.682 1.00 0.00  ? 463 CYS B O   1 
ATOM 4896 C CB  . CYS B 1 463 ? 106.389 149.057 140.989 1.00 0.61  ? 463 CYS B CB  1 
ATOM 4897 S SG  . CYS B 1 463 ? 107.918 148.095 141.109 1.00 3.37  ? 463 CYS B SG  1 
ATOM 4898 N N   . LEU B 1 464 ? 104.506 151.630 140.688 1.00 3.81  ? 464 LEU B N   1 
ATOM 4899 C CA  . LEU B 1 464 ? 103.224 152.251 140.362 1.00 3.69  ? 464 LEU B CA  1 
ATOM 4900 C C   . LEU B 1 464 ? 103.366 153.246 139.215 1.00 2.45  ? 464 LEU B C   1 
ATOM 4901 O O   . LEU B 1 464 ? 102.514 153.302 138.319 1.00 7.61  ? 464 LEU B O   1 
ATOM 4902 C CB  . LEU B 1 464 ? 102.641 152.940 141.595 1.00 1.75  ? 464 LEU B CB  1 
ATOM 4903 C CG  . LEU B 1 464 ? 102.073 152.041 142.694 1.00 1.48  ? 464 LEU B CG  1 
ATOM 4904 C CD1 . LEU B 1 464 ? 101.074 152.808 143.541 1.00 4.66  ? 464 LEU B CD1 1 
ATOM 4905 C CD2 . LEU B 1 464 ? 101.432 150.798 142.102 1.00 2.29  ? 464 LEU B CD2 1 
ATOM 4906 N N   . ARG B 1 465 ? 104.438 154.042 139.225 1.00 1.78  ? 465 ARG B N   1 
ATOM 4907 C CA  . ARG B 1 465 ? 104.675 154.984 138.135 1.00 2.72  ? 465 ARG B CA  1 
ATOM 4908 C C   . ARG B 1 465 ? 104.920 154.256 136.817 1.00 4.82  ? 465 ARG B C   1 
ATOM 4909 O O   . ARG B 1 465 ? 104.435 154.683 135.761 1.00 6.86  ? 465 ARG B O   1 
ATOM 4910 C CB  . ARG B 1 465 ? 105.855 155.893 138.484 1.00 3.46  ? 465 ARG B CB  1 
ATOM 4911 C CG  . ARG B 1 465 ? 106.460 156.619 137.300 1.00 5.37  ? 465 ARG B CG  1 
ATOM 4912 C CD  . ARG B 1 465 ? 105.755 157.937 137.046 1.00 4.27  ? 465 ARG B CD  1 
ATOM 4913 N NE  . ARG B 1 465 ? 106.137 158.520 135.766 1.00 7.01  ? 465 ARG B NE  1 
ATOM 4914 C CZ  . ARG B 1 465 ? 106.476 159.789 135.593 1.00 1.80  ? 465 ARG B CZ  1 
ATOM 4915 N NH1 . ARG B 1 465 ? 106.496 160.643 136.601 1.00 5.48  ? 465 ARG B NH1 1 
ATOM 4916 N NH2 . ARG B 1 465 ? 106.803 160.212 134.376 1.00 3.65  ? 465 ARG B NH2 1 
ATOM 4917 N N   . ARG B 1 466 ? 105.675 153.155 136.857 1.00 5.47  ? 466 ARG B N   1 
ATOM 4918 C CA  . ARG B 1 466 ? 105.909 152.377 135.643 1.00 0.00  ? 466 ARG B CA  1 
ATOM 4919 C C   . ARG B 1 466 ? 104.613 151.782 135.111 1.00 2.39  ? 466 ARG B C   1 
ATOM 4920 O O   . ARG B 1 466 ? 104.402 151.726 133.894 1.00 7.10  ? 466 ARG B O   1 
ATOM 4921 C CB  . ARG B 1 466 ? 106.933 151.275 135.906 1.00 0.00  ? 466 ARG B CB  1 
ATOM 4922 C CG  . ARG B 1 466 ? 108.371 151.752 135.949 1.00 0.00  ? 466 ARG B CG  1 
ATOM 4923 C CD  . ARG B 1 466 ? 109.323 150.585 135.788 1.00 0.00  ? 466 ARG B CD  1 
ATOM 4924 N NE  . ARG B 1 466 ? 109.604 150.311 134.385 1.00 3.01  ? 466 ARG B NE  1 
ATOM 4925 C CZ  . ARG B 1 466 ? 110.196 149.213 133.939 1.00 1.72  ? 466 ARG B CZ  1 
ATOM 4926 N NH1 . ARG B 1 466 ? 110.593 148.258 134.764 1.00 0.00  ? 466 ARG B NH1 1 
ATOM 4927 N NH2 . ARG B 1 466 ? 110.399 149.070 132.633 1.00 0.00  ? 466 ARG B NH2 1 
ATOM 4928 N N   . TYR B 1 467 ? 103.741 151.313 136.006 1.00 3.80  ? 467 TYR B N   1 
ATOM 4929 C CA  . TYR B 1 467 ? 102.443 150.814 135.567 1.00 4.01  ? 467 TYR B CA  1 
ATOM 4930 C C   . TYR B 1 467 ? 101.609 151.926 134.944 1.00 6.93  ? 467 TYR B C   1 
ATOM 4931 O O   . TYR B 1 467 ? 100.922 151.708 133.941 1.00 6.74  ? 467 TYR B O   1 
ATOM 4932 C CB  . TYR B 1 467 ? 101.690 150.178 136.733 1.00 4.40  ? 467 TYR B CB  1 
ATOM 4933 C CG  . TYR B 1 467 ? 100.231 149.939 136.425 1.00 9.26  ? 467 TYR B CG  1 
ATOM 4934 C CD1 . TYR B 1 467 ? 99.843  148.928 135.557 1.00 7.11  ? 467 TYR B CD1 1 
ATOM 4935 C CD2 . TYR B 1 467 ? 99.241  150.727 136.998 1.00 7.09  ? 467 TYR B CD2 1 
ATOM 4936 C CE1 . TYR B 1 467 ? 98.513  148.708 135.267 1.00 4.74  ? 467 TYR B CE1 1 
ATOM 4937 C CE2 . TYR B 1 467 ? 97.906  150.513 136.714 1.00 4.38  ? 467 TYR B CE2 1 
ATOM 4938 C CZ  . TYR B 1 467 ? 97.548  149.501 135.849 1.00 5.63  ? 467 TYR B CZ  1 
ATOM 4939 O OH  . TYR B 1 467 ? 96.221  149.282 135.563 1.00 11.81 ? 467 TYR B OH  1 
ATOM 4940 N N   . ARG B 1 468 ? 101.630 153.183 135.380 1.00 6.74  ? 468 ARG B N   1 
ATOM 4941 C CA  . ARG B 1 468 ? 100.826 154.241 134.760 1.00 2.91  ? 468 ARG B CA  1 
ATOM 4942 C C   . ARG B 1 468 ? 101.500 154.713 133.515 1.00 8.28  ? 468 ARG B C   1 
ATOM 4943 O O   . ARG B 1 468 ? 100.856 155.426 132.730 1.00 9.13  ? 468 ARG B O   1 
ATOM 4944 C CB  . ARG B 1 468 ? 100.978 155.584 135.442 1.00 5.60  ? 468 ARG B CB  1 
ATOM 4945 C CG  . ARG B 1 468 ? 99.773  156.493 135.624 1.00 7.28  ? 468 ARG B CG  1 
ATOM 4946 C CD  . ARG B 1 468 ? 100.271 157.916 135.613 1.00 7.65  ? 468 ARG B CD  1 
ATOM 4947 N NE  . ARG B 1 468 ? 101.461 158.060 134.769 1.00 10.72 ? 468 ARG B NE  1 
ATOM 4948 C CZ  . ARG B 1 468 ? 101.838 159.212 134.243 1.00 13.34 ? 468 ARG B CZ  1 
ATOM 4949 N NH1 . ARG B 1 468 ? 100.925 160.097 133.912 1.00 9.85  ? 468 ARG B NH1 1 
ATOM 4950 N NH2 . ARG B 1 468 ? 103.116 159.497 134.081 1.00 12.23 ? 468 ARG B NH2 1 
ATOM 4951 N N   . ASP B 1 469 ? 102.790 154.447 133.360 1.00 6.47  ? 469 ASP B N   1 
ATOM 4952 C CA  . ASP B 1 469 ? 103.388 154.784 132.072 1.00 2.18  ? 469 ASP B CA  1 
ATOM 4953 C C   . ASP B 1 469 ? 103.116 153.720 131.011 1.00 5.33  ? 469 ASP B C   1 
ATOM 4954 O O   . ASP B 1 469 ? 102.905 154.053 129.840 1.00 11.32 ? 469 ASP B O   1 
ATOM 4955 C CB  . ASP B 1 469 ? 104.892 155.003 132.234 1.00 2.86  ? 469 ASP B CB  1 
ATOM 4956 C CG  . ASP B 1 469 ? 105.233 156.430 132.609 1.00 5.43  ? 469 ASP B CG  1 
ATOM 4957 O OD1 . ASP B 1 469 ? 104.381 157.317 132.400 1.00 8.93  ? 469 ASP B OD1 1 
ATOM 4958 O OD2 . ASP B 1 469 ? 106.350 156.665 133.116 1.00 7.12  ? 469 ASP B OD2 1 
ATOM 4959 N N   . THR B 1 470 ? 103.115 152.441 131.394 1.00 9.69  ? 470 THR B N   1 
ATOM 4960 C CA  . THR B 1 470 ? 103.002 151.352 130.431 1.00 5.72  ? 470 THR B CA  1 
ATOM 4961 C C   . THR B 1 470 ? 101.648 150.655 130.425 1.00 7.44  ? 470 THR B C   1 
ATOM 4962 O O   . THR B 1 470 ? 101.330 149.984 129.439 1.00 11.51 ? 470 THR B O   1 
ATOM 4963 C CB  . THR B 1 470 ? 104.089 150.296 130.687 1.00 7.73  ? 470 THR B CB  1 
ATOM 4964 O OG1 . THR B 1 470 ? 103.893 149.710 131.980 1.00 8.01  ? 470 THR B OG1 1 
ATOM 4965 C CG2 . THR B 1 470 ? 105.472 150.925 130.624 1.00 7.22  ? 470 THR B CG2 1 
ATOM 4966 N N   . LYS B 1 471 ? 100.854 150.794 131.488 1.00 5.17  ? 471 LYS B N   1 
ATOM 4967 C CA  . LYS B 1 471 ? 99.534  150.163 131.588 1.00 3.66  ? 471 LYS B CA  1 
ATOM 4968 C C   . LYS B 1 471 ? 99.613  148.650 131.390 1.00 9.08  ? 471 LYS B C   1 
ATOM 4969 O O   . LYS B 1 471 ? 98.781  148.050 130.707 1.00 13.34 ? 471 LYS B O   1 
ATOM 4970 C CB  . LYS B 1 471 ? 98.542  150.788 130.604 1.00 4.38  ? 471 LYS B CB  1 
ATOM 4971 C CG  . LYS B 1 471 ? 98.602  152.303 130.548 1.00 6.61  ? 471 LYS B CG  1 
ATOM 4972 C CD  . LYS B 1 471 ? 98.161  152.916 131.866 1.00 8.14  ? 471 LYS B CD  1 
ATOM 4973 C CE  . LYS B 1 471 ? 96.679  152.684 132.117 1.00 9.16  ? 471 LYS B CE  1 
ATOM 4974 N NZ  . LYS B 1 471 ? 96.266  153.156 133.467 1.00 8.91  ? 471 LYS B NZ  1 
ATOM 4975 N N   . ARG B 1 472 ? 100.622 148.028 131.993 1.00 4.91  ? 472 ARG B N   1 
ATOM 4976 C CA  . ARG B 1 472 ? 100.780 146.577 131.982 1.00 5.77  ? 472 ARG B CA  1 
ATOM 4977 C C   . ARG B 1 472 ? 100.741 146.090 133.424 1.00 10.21 ? 472 ARG B C   1 
ATOM 4978 O O   . ARG B 1 472 ? 101.634 146.409 134.215 1.00 12.05 ? 472 ARG B O   1 
ATOM 4979 C CB  . ARG B 1 472 ? 102.081 146.167 131.295 1.00 6.42  ? 472 ARG B CB  1 
ATOM 4980 C CG  . ARG B 1 472 ? 102.366 146.925 130.010 1.00 8.24  ? 472 ARG B CG  1 
ATOM 4981 C CD  . ARG B 1 472 ? 103.568 146.349 129.283 1.00 6.96  ? 472 ARG B CD  1 
ATOM 4982 N NE  . ARG B 1 472 ? 103.582 144.892 129.317 1.00 6.66  ? 472 ARG B NE  1 
ATOM 4983 C CZ  . ARG B 1 472 ? 104.643 144.164 129.636 1.00 10.47 ? 472 ARG B CZ  1 
ATOM 4984 N NH1 . ARG B 1 472 ? 105.790 144.728 129.972 1.00 10.51 ? 472 ARG B NH1 1 
ATOM 4985 N NH2 . ARG B 1 472 ? 104.550 142.838 129.619 1.00 9.86  ? 472 ARG B NH2 1 
ATOM 4986 N N   . ALA B 1 473 ? 99.700  145.326 133.766 1.00 7.37  ? 473 ALA B N   1 
ATOM 4987 C CA  . ALA B 1 473 ? 99.589  144.793 135.119 1.00 8.98  ? 473 ALA B CA  1 
ATOM 4988 C C   . ALA B 1 473 ? 100.762 143.877 135.443 1.00 9.79  ? 473 ALA B C   1 
ATOM 4989 O O   . ALA B 1 473 ? 101.322 143.936 136.545 1.00 9.01  ? 473 ALA B O   1 
ATOM 4990 C CB  . ALA B 1 473 ? 98.262  144.054 135.286 1.00 7.93  ? 473 ALA B CB  1 
ATOM 4991 N N   . PHE B 1 474 ? 101.147 143.023 134.500 1.00 5.40  ? 474 PHE B N   1 
ATOM 4992 C CA  . PHE B 1 474 ? 102.374 142.265 134.687 1.00 5.67  ? 474 PHE B CA  1 
ATOM 4993 C C   . PHE B 1 474 ? 103.529 142.951 133.970 1.00 8.32  ? 474 PHE B C   1 
ATOM 4994 O O   . PHE B 1 474 ? 103.375 143.388 132.825 1.00 13.08 ? 474 PHE B O   1 
ATOM 4995 C CB  . PHE B 1 474 ? 102.228 140.837 134.161 1.00 2.81  ? 474 PHE B CB  1 
ATOM 4996 C CG  . PHE B 1 474 ? 103.283 139.894 134.668 1.00 8.53  ? 474 PHE B CG  1 
ATOM 4997 C CD1 . PHE B 1 474 ? 103.114 139.226 135.868 1.00 7.95  ? 474 PHE B CD1 1 
ATOM 4998 C CD2 . PHE B 1 474 ? 104.447 139.683 133.949 1.00 6.39  ? 474 PHE B CD2 1 
ATOM 4999 C CE1 . PHE B 1 474 ? 104.085 138.363 136.342 1.00 7.61  ? 474 PHE B CE1 1 
ATOM 5000 C CE2 . PHE B 1 474 ? 105.421 138.821 134.418 1.00 5.53  ? 474 PHE B CE2 1 
ATOM 5001 C CZ  . PHE B 1 474 ? 105.239 138.161 135.615 1.00 6.69  ? 474 PHE B CZ  1 
ATOM 5002 N N   . PRO B 1 475 ? 104.699 143.061 134.608 1.00 7.23  ? 475 PRO B N   1 
ATOM 5003 C CA  . PRO B 1 475 ? 105.037 142.606 135.958 1.00 3.10  ? 475 PRO B CA  1 
ATOM 5004 C C   . PRO B 1 475 ? 105.001 143.713 137.007 1.00 4.97  ? 475 PRO B C   1 
ATOM 5005 O O   . PRO B 1 475 ? 105.336 143.473 138.162 1.00 8.14  ? 475 PRO B O   1 
ATOM 5006 C CB  . PRO B 1 475 ? 106.458 142.074 135.765 1.00 4.43  ? 475 PRO B CB  1 
ATOM 5007 C CG  . PRO B 1 475 ? 107.055 143.036 134.756 1.00 4.20  ? 475 PRO B CG  1 
ATOM 5008 C CD  . PRO B 1 475 ? 105.900 143.533 133.896 1.00 5.44  ? 475 PRO B CD  1 
ATOM 5009 N N   . HIS B 1 476 ? 104.601 144.930 136.632 1.00 2.68  ? 476 HIS B N   1 
ATOM 5010 C CA  . HIS B 1 476 ? 104.798 146.083 137.508 1.00 2.56  ? 476 HIS B CA  1 
ATOM 5011 C C   . HIS B 1 476 ? 103.929 146.007 138.760 1.00 5.52  ? 476 HIS B C   1 
ATOM 5012 O O   . HIS B 1 476 ? 104.395 146.323 139.861 1.00 7.18  ? 476 HIS B O   1 
ATOM 5013 C CB  . HIS B 1 476 ? 104.533 147.371 136.732 1.00 1.28  ? 476 HIS B CB  1 
ATOM 5014 C CG  . HIS B 1 476 ? 105.366 147.506 135.497 1.00 1.55  ? 476 HIS B CG  1 
ATOM 5015 N ND1 . HIS B 1 476 ? 106.734 147.342 135.502 1.00 2.89  ? 476 HIS B ND1 1 
ATOM 5016 C CD2 . HIS B 1 476 ? 105.025 147.778 134.215 1.00 5.09  ? 476 HIS B CD2 1 
ATOM 5017 C CE1 . HIS B 1 476 ? 107.201 147.511 134.278 1.00 0.00  ? 476 HIS B CE1 1 
ATOM 5018 N NE2 . HIS B 1 476 ? 106.185 147.777 133.478 1.00 3.79  ? 476 HIS B NE2 1 
ATOM 5019 N N   . LEU B 1 477 ? 102.668 145.593 138.618 1.00 6.86  ? 477 LEU B N   1 
ATOM 5020 C CA  . LEU B 1 477 ? 101.807 145.464 139.790 1.00 2.36  ? 477 LEU B CA  1 
ATOM 5021 C C   . LEU B 1 477 ? 102.221 144.287 140.665 1.00 4.04  ? 477 LEU B C   1 
ATOM 5022 O O   . LEU B 1 477 ? 102.126 144.365 141.896 1.00 7.05  ? 477 LEU B O   1 
ATOM 5023 C CB  . LEU B 1 477 ? 100.346 145.326 139.359 1.00 6.93  ? 477 LEU B CB  1 
ATOM 5024 C CG  . LEU B 1 477 ? 99.731  146.528 138.637 1.00 5.78  ? 477 LEU B CG  1 
ATOM 5025 C CD1 . LEU B 1 477 ? 98.214  146.483 138.717 1.00 4.42  ? 477 LEU B CD1 1 
ATOM 5026 C CD2 . LEU B 1 477 ? 100.255 147.837 139.201 1.00 4.43  ? 477 LEU B CD2 1 
ATOM 5027 N N   . VAL B 1 478 ? 102.686 143.197 140.054 1.00 1.96  ? 478 VAL B N   1 
ATOM 5028 C CA  . VAL B 1 478 ? 103.227 142.081 140.825 1.00 1.73  ? 478 VAL B CA  1 
ATOM 5029 C C   . VAL B 1 478 ? 104.470 142.518 141.593 1.00 2.14  ? 478 VAL B C   1 
ATOM 5030 O O   . VAL B 1 478 ? 104.661 142.153 142.761 1.00 5.38  ? 478 VAL B O   1 
ATOM 5031 C CB  . VAL B 1 478 ? 103.515 140.891 139.891 1.00 4.11  ? 478 VAL B CB  1 
ATOM 5032 C CG1 . VAL B 1 478 ? 103.756 139.626 140.692 1.00 1.11  ? 478 VAL B CG1 1 
ATOM 5033 C CG2 . VAL B 1 478 ? 102.357 140.699 138.932 1.00 5.39  ? 478 VAL B CG2 1 
ATOM 5034 N N   . ASN B 1 479 ? 105.331 143.311 140.952 1.00 1.03  ? 479 ASN B N   1 
ATOM 5035 C CA  . ASN B 1 479 ? 106.492 143.863 141.642 1.00 0.57  ? 479 ASN B CA  1 
ATOM 5036 C C   . ASN B 1 479 ? 106.068 144.763 142.799 1.00 0.00  ? 479 ASN B C   1 
ATOM 5037 O O   . ASN B 1 479 ? 106.678 144.735 143.875 1.00 0.57  ? 479 ASN B O   1 
ATOM 5038 C CB  . ASN B 1 479 ? 107.368 144.629 140.650 1.00 2.17  ? 479 ASN B CB  1 
ATOM 5039 C CG  . ASN B 1 479 ? 108.839 144.289 140.783 1.00 0.00  ? 479 ASN B CG  1 
ATOM 5040 O OD1 . ASN B 1 479 ? 109.249 143.622 141.729 1.00 0.00  ? 479 ASN B OD1 1 
ATOM 5041 N ND2 . ASN B 1 479 ? 109.642 144.759 139.837 1.00 0.00  ? 479 ASN B ND2 1 
ATOM 5042 N N   . ALA B 1 480 ? 105.019 145.566 142.597 1.00 2.17  ? 480 ALA B N   1 
ATOM 5043 C CA  . ALA B 1 480 ? 104.513 146.411 143.675 1.00 2.12  ? 480 ALA B CA  1 
ATOM 5044 C C   . ALA B 1 480 ? 104.009 145.574 144.846 1.00 1.75  ? 480 ALA B C   1 
ATOM 5045 O O   . ALA B 1 480 ? 104.247 145.916 146.009 1.00 2.95  ? 480 ALA B O   1 
ATOM 5046 C CB  . ALA B 1 480 ? 103.406 147.326 143.152 1.00 0.25  ? 480 ALA B CB  1 
ATOM 5047 N N   . GLY B 1 481 ? 103.307 144.477 144.561 1.00 1.86  ? 481 GLY B N   1 
ATOM 5048 C CA  . GLY B 1 481 ? 102.887 143.584 145.632 1.00 2.09  ? 481 GLY B CA  1 
ATOM 5049 C C   . GLY B 1 481 ? 104.063 142.972 146.373 1.00 3.70  ? 481 GLY B C   1 
ATOM 5050 O O   . GLY B 1 481 ? 104.038 142.832 147.603 1.00 4.50  ? 481 GLY B O   1 
ATOM 5051 N N   . LYS B 1 482 ? 105.111 142.603 145.632 1.00 0.00  ? 482 LYS B N   1 
ATOM 5052 C CA  . LYS B 1 482 ? 106.328 142.102 146.262 1.00 0.00  ? 482 LYS B CA  1 
ATOM 5053 C C   . LYS B 1 482 ? 106.919 143.139 147.210 1.00 1.29  ? 482 LYS B C   1 
ATOM 5054 O O   . LYS B 1 482 ? 107.343 142.809 148.323 1.00 0.70  ? 482 LYS B O   1 
ATOM 5055 C CB  . LYS B 1 482 ? 107.351 141.708 145.195 1.00 0.00  ? 482 LYS B CB  1 
ATOM 5056 C CG  . LYS B 1 482 ? 108.554 140.957 145.741 1.00 0.73  ? 482 LYS B CG  1 
ATOM 5057 C CD  . LYS B 1 482 ? 109.719 140.962 144.768 1.00 3.48  ? 482 LYS B CD  1 
ATOM 5058 C CE  . LYS B 1 482 ? 110.270 142.362 144.555 1.00 2.64  ? 482 LYS B CE  1 
ATOM 5059 N NZ  . LYS B 1 482 ? 111.345 142.380 143.529 1.00 0.00  ? 482 LYS B NZ  1 
ATOM 5060 N N   . TYR B 1 483 ? 106.949 144.404 146.784 1.00 0.00  ? 483 TYR B N   1 
ATOM 5061 C CA  . TYR B 1 483 ? 107.503 145.455 147.632 1.00 0.00  ? 483 TYR B CA  1 
ATOM 5062 C C   . TYR B 1 483 ? 106.546 145.887 148.739 1.00 2.93  ? 483 TYR B C   1 
ATOM 5063 O O   . TYR B 1 483 ? 106.960 146.615 149.645 1.00 2.59  ? 483 TYR B O   1 
ATOM 5064 C CB  . TYR B 1 483 ? 107.909 146.662 146.782 1.00 0.00  ? 483 TYR B CB  1 
ATOM 5065 C CG  . TYR B 1 483 ? 109.142 146.401 145.952 1.00 0.00  ? 483 TYR B CG  1 
ATOM 5066 C CD1 . TYR B 1 483 ? 110.354 146.098 146.557 1.00 0.00  ? 483 TYR B CD1 1 
ATOM 5067 C CD2 . TYR B 1 483 ? 109.091 146.432 144.565 1.00 0.00  ? 483 TYR B CD2 1 
ATOM 5068 C CE1 . TYR B 1 483 ? 111.481 145.845 145.808 1.00 0.00  ? 483 TYR B CE1 1 
ATOM 5069 C CE2 . TYR B 1 483 ? 110.214 146.179 143.807 1.00 0.00  ? 483 TYR B CE2 1 
ATOM 5070 C CZ  . TYR B 1 483 ? 111.407 145.885 144.434 1.00 0.00  ? 483 TYR B CZ  1 
ATOM 5071 O OH  . TYR B 1 483 ? 112.531 145.633 143.686 1.00 0.00  ? 483 TYR B OH  1 
ATOM 5072 N N   . SER B 1 484 ? 105.277 145.487 148.672 1.00 2.73  ? 484 SER B N   1 
ATOM 5073 C CA  . SER B 1 484 ? 104.337 145.740 149.759 1.00 1.36  ? 484 SER B CA  1 
ATOM 5074 C C   . SER B 1 484 ? 104.321 144.628 150.804 1.00 2.47  ? 484 SER B C   1 
ATOM 5075 O O   . SER B 1 484 ? 103.840 144.849 151.930 1.00 3.62  ? 484 SER B O   1 
ATOM 5076 C CB  . SER B 1 484 ? 102.924 145.936 149.196 1.00 1.91  ? 484 SER B CB  1 
ATOM 5077 O OG  . SER B 1 484 ? 102.271 144.694 149.011 1.00 9.73  ? 484 SER B OG  1 
ATOM 5078 N N   . THR B 1 485 ? 104.811 143.438 150.446 1.00 4.42  ? 485 THR B N   1 
ATOM 5079 C CA  . THR B 1 485 ? 104.929 142.368 151.435 1.00 0.50  ? 485 THR B CA  1 
ATOM 5080 C C   . THR B 1 485 ? 105.745 142.815 152.645 1.00 1.80  ? 485 THR B C   1 
ATOM 5081 O O   . THR B 1 485 ? 105.418 142.465 153.786 1.00 4.68  ? 485 THR B O   1 
ATOM 5082 C CB  . THR B 1 485 ? 105.557 141.121 150.812 1.00 1.05  ? 485 THR B CB  1 
ATOM 5083 O OG1 . THR B 1 485 ? 106.854 141.440 150.292 1.00 4.70  ? 485 THR B OG1 1 
ATOM 5084 C CG2 . THR B 1 485 ? 104.677 140.571 149.706 1.00 1.40  ? 485 THR B CG2 1 
ATOM 5085 N N   . THR B 1 486 ? 106.814 143.585 152.419 1.00 5.57  ? 486 THR B N   1 
ATOM 5086 C CA  . THR B 1 486 ? 107.611 144.073 153.540 1.00 4.52  ? 486 THR B CA  1 
ATOM 5087 C C   . THR B 1 486 ? 106.854 145.101 154.373 1.00 1.78  ? 486 THR B C   1 
ATOM 5088 O O   . THR B 1 486 ? 107.043 145.156 155.592 1.00 1.89  ? 486 THR B O   1 
ATOM 5089 C CB  . THR B 1 486 ? 108.942 144.650 153.050 1.00 3.28  ? 486 THR B CB  1 
ATOM 5090 O OG1 . THR B 1 486 ? 109.700 143.631 152.385 1.00 8.02  ? 486 THR B OG1 1 
ATOM 5091 C CG2 . THR B 1 486 ? 109.738 145.206 154.194 1.00 5.54  ? 486 THR B CG2 1 
ATOM 5092 N N   . PHE B 1 487 ? 105.999 145.917 153.746 1.00 5.72  ? 487 PHE B N   1 
ATOM 5093 C CA  . PHE B 1 487 ? 105.114 146.783 154.521 1.00 1.95  ? 487 PHE B CA  1 
ATOM 5094 C C   . PHE B 1 487 ? 104.272 145.959 155.481 1.00 4.40  ? 487 PHE B C   1 
ATOM 5095 O O   . PHE B 1 487 ? 104.200 146.255 156.681 1.00 2.54  ? 487 PHE B O   1 
ATOM 5096 C CB  . PHE B 1 487 ? 104.193 147.588 153.601 1.00 4.07  ? 487 PHE B CB  1 
ATOM 5097 C CG  . PHE B 1 487 ? 104.907 148.513 152.669 1.00 1.57  ? 487 PHE B CG  1 
ATOM 5098 C CD1 . PHE B 1 487 ? 106.145 149.036 152.993 1.00 2.76  ? 487 PHE B CD1 1 
ATOM 5099 C CD2 . PHE B 1 487 ? 104.330 148.866 151.462 1.00 3.01  ? 487 PHE B CD2 1 
ATOM 5100 C CE1 . PHE B 1 487 ? 106.791 149.888 152.129 1.00 6.05  ? 487 PHE B CE1 1 
ATOM 5101 C CE2 . PHE B 1 487 ? 104.974 149.716 150.592 1.00 1.26  ? 487 PHE B CE2 1 
ATOM 5102 C CZ  . PHE B 1 487 ? 106.204 150.226 150.926 1.00 5.80  ? 487 PHE B CZ  1 
ATOM 5103 N N   . PHE B 1 488 ? 103.627 144.912 154.961 1.00 8.44  ? 488 PHE B N   1 
ATOM 5104 C CA  . PHE B 1 488 ? 102.784 144.078 155.816 1.00 3.31  ? 488 PHE B CA  1 
ATOM 5105 C C   . PHE B 1 488 ? 103.597 143.423 156.929 1.00 2.91  ? 488 PHE B C   1 
ATOM 5106 O O   . PHE B 1 488 ? 103.169 143.394 158.091 1.00 5.39  ? 488 PHE B O   1 
ATOM 5107 C CB  . PHE B 1 488 ? 102.060 143.018 154.986 1.00 2.76  ? 488 PHE B CB  1 
ATOM 5108 C CG  . PHE B 1 488 ? 100.939 143.563 154.148 1.00 4.97  ? 488 PHE B CG  1 
ATOM 5109 C CD1 . PHE B 1 488 ? 99.697  143.810 154.708 1.00 7.28  ? 488 PHE B CD1 1 
ATOM 5110 C CD2 . PHE B 1 488 ? 101.121 143.819 152.800 1.00 2.99  ? 488 PHE B CD2 1 
ATOM 5111 C CE1 . PHE B 1 488 ? 98.661  144.310 153.941 1.00 6.97  ? 488 PHE B CE1 1 
ATOM 5112 C CE2 . PHE B 1 488 ? 100.091 144.319 152.027 1.00 6.31  ? 488 PHE B CE2 1 
ATOM 5113 C CZ  . PHE B 1 488 ? 98.859  144.564 152.598 1.00 3.79  ? 488 PHE B CZ  1 
ATOM 5114 N N   . MET B 1 489 ? 104.781 142.906 156.592 1.00 3.09  ? 489 MET B N   1 
ATOM 5115 C CA  . MET B 1 489 ? 105.607 142.217 157.578 1.00 2.66  ? 489 MET B CA  1 
ATOM 5116 C C   . MET B 1 489 ? 106.040 143.159 158.696 1.00 1.82  ? 489 MET B C   1 
ATOM 5117 O O   . MET B 1 489 ? 105.932 142.824 159.882 1.00 2.23  ? 489 MET B O   1 
ATOM 5118 C CB  . MET B 1 489 ? 106.825 141.596 156.894 1.00 4.91  ? 489 MET B CB  1 
ATOM 5119 C CG  . MET B 1 489 ? 107.312 140.312 157.538 1.00 3.06  ? 489 MET B CG  1 
ATOM 5120 S SD  . MET B 1 489 ? 108.991 139.869 157.053 1.00 8.14  ? 489 MET B SD  1 
ATOM 5121 C CE  . MET B 1 489 ? 109.824 141.437 157.247 1.00 3.34  ? 489 MET B CE  1 
ATOM 5122 N N   . VAL B 1 490 ? 106.526 144.350 158.334 1.00 0.72  ? 490 VAL B N   1 
ATOM 5123 C CA  . VAL B 1 490 ? 106.980 145.308 159.336 1.00 0.89  ? 490 VAL B CA  1 
ATOM 5124 C C   . VAL B 1 490 ? 105.814 145.779 160.195 1.00 4.76  ? 490 VAL B C   1 
ATOM 5125 O O   . VAL B 1 490 ? 105.943 145.915 161.419 1.00 1.84  ? 490 VAL B O   1 
ATOM 5126 C CB  . VAL B 1 490 ? 107.702 146.488 158.657 1.00 2.24  ? 490 VAL B CB  1 
ATOM 5127 C CG1 . VAL B 1 490 ? 107.872 147.647 159.626 1.00 0.52  ? 490 VAL B CG1 1 
ATOM 5128 C CG2 . VAL B 1 490 ? 109.050 146.042 158.114 1.00 3.34  ? 490 VAL B CG2 1 
ATOM 5129 N N   . THR B 1 491 ? 104.658 146.033 159.575 1.00 1.67  ? 491 THR B N   1 
ATOM 5130 C CA  . THR B 1 491 ? 103.500 146.473 160.343 1.00 2.20  ? 491 THR B CA  1 
ATOM 5131 C C   . THR B 1 491 ? 103.093 145.425 161.367 1.00 5.69  ? 491 THR B C   1 
ATOM 5132 O O   . THR B 1 491 ? 102.831 145.750 162.533 1.00 6.20  ? 491 THR B O   1 
ATOM 5133 C CB  . THR B 1 491 ? 102.335 146.786 159.405 1.00 2.23  ? 491 THR B CB  1 
ATOM 5134 O OG1 . THR B 1 491 ? 102.687 147.883 158.554 1.00 8.01  ? 491 THR B OG1 1 
ATOM 5135 C CG2 . THR B 1 491 ? 101.091 147.148 160.200 1.00 3.79  ? 491 THR B CG2 1 
ATOM 5136 N N   . PHE B 1 492 ? 103.058 144.155 160.962 1.00 5.94  ? 492 PHE B N   1 
ATOM 5137 C CA  . PHE B 1 492 ? 102.619 143.120 161.890 1.00 3.77  ? 492 PHE B CA  1 
ATOM 5138 C C   . PHE B 1 492 ? 103.661 142.862 162.973 1.00 2.99  ? 492 PHE B C   1 
ATOM 5139 O O   . PHE B 1 492 ? 103.305 142.592 164.126 1.00 10.30 ? 492 PHE B O   1 
ATOM 5140 C CB  . PHE B 1 492 ? 102.271 141.849 161.122 1.00 1.78  ? 492 PHE B CB  1 
ATOM 5141 C CG  . PHE B 1 492 ? 100.920 141.905 160.472 1.00 2.01  ? 492 PHE B CG  1 
ATOM 5142 C CD1 . PHE B 1 492 ? 99.804  142.263 161.209 1.00 6.36  ? 492 PHE B CD1 1 
ATOM 5143 C CD2 . PHE B 1 492 ? 100.767 141.640 159.124 1.00 2.87  ? 492 PHE B CD2 1 
ATOM 5144 C CE1 . PHE B 1 492 ? 98.557  142.331 160.619 1.00 8.02  ? 492 PHE B CE1 1 
ATOM 5145 C CE2 . PHE B 1 492 ? 99.522  141.712 158.529 1.00 3.37  ? 492 PHE B CE2 1 
ATOM 5146 C CZ  . PHE B 1 492 ? 98.417  142.056 159.277 1.00 5.04  ? 492 PHE B CZ  1 
ATOM 5147 N N   . ALA B 1 493 ? 104.950 142.968 162.636 1.00 2.53  ? 493 ALA B N   1 
ATOM 5148 C CA  . ALA B 1 493 ? 105.983 142.840 163.660 1.00 2.31  ? 493 ALA B CA  1 
ATOM 5149 C C   . ALA B 1 493 ? 105.874 143.952 164.699 1.00 7.37  ? 493 ALA B C   1 
ATOM 5150 O O   . ALA B 1 493 ? 105.979 143.699 165.908 1.00 5.01  ? 493 ALA B O   1 
ATOM 5151 C CB  . ALA B 1 493 ? 107.367 142.839 163.014 1.00 2.24  ? 493 ALA B CB  1 
ATOM 5152 N N   . ALA B 1 494 ? 105.655 145.191 164.248 1.00 5.19  ? 494 ALA B N   1 
ATOM 5153 C CA  . ALA B 1 494 ? 105.508 146.302 165.183 1.00 0.58  ? 494 ALA B CA  1 
ATOM 5154 C C   . ALA B 1 494 ? 104.259 146.146 166.043 1.00 7.88  ? 494 ALA B C   1 
ATOM 5155 O O   . ALA B 1 494 ? 104.287 146.432 167.246 1.00 11.83 ? 494 ALA B O   1 
ATOM 5156 C CB  . ALA B 1 494 ? 105.480 147.628 164.425 1.00 2.63  ? 494 ALA B CB  1 
ATOM 5157 N N   . LEU B 1 495 ? 103.150 145.701 165.444 1.00 6.72  ? 495 LEU B N   1 
ATOM 5158 C CA  . LEU B 1 495 ? 101.929 145.501 166.219 1.00 2.84  ? 495 LEU B CA  1 
ATOM 5159 C C   . LEU B 1 495 ? 102.109 144.403 167.262 1.00 9.29  ? 495 LEU B C   1 
ATOM 5160 O O   . LEU B 1 495 ? 101.644 144.539 168.401 1.00 9.56  ? 495 LEU B O   1 
ATOM 5161 C CB  . LEU B 1 495 ? 100.762 145.179 165.287 1.00 6.15  ? 495 LEU B CB  1 
ATOM 5162 C CG  . LEU B 1 495 ? 100.136 146.384 164.581 1.00 5.62  ? 495 LEU B CG  1 
ATOM 5163 C CD1 . LEU B 1 495 ? 98.969  145.954 163.709 1.00 4.12  ? 495 LEU B CD1 1 
ATOM 5164 C CD2 . LEU B 1 495 ? 99.697  147.433 165.593 1.00 7.23  ? 495 LEU B CD2 1 
ATOM 5165 N N   . TYR B 1 496 ? 102.782 143.311 166.895 1.00 7.40  ? 496 TYR B N   1 
ATOM 5166 C CA  . TYR B 1 496 ? 103.076 142.248 167.844 1.00 3.41  ? 496 TYR B CA  1 
ATOM 5167 C C   . TYR B 1 496 ? 103.982 142.706 168.976 1.00 6.58  ? 496 TYR B C   1 
ATOM 5168 O O   . TYR B 1 496 ? 103.751 142.314 170.124 1.00 11.65 ? 496 TYR B O   1 
ATOM 5169 C CB  . TYR B 1 496 ? 103.710 141.056 167.122 1.00 8.72  ? 496 TYR B CB  1 
ATOM 5170 C CG  . TYR B 1 496 ? 104.362 140.049 168.043 1.00 11.58 ? 496 TYR B CG  1 
ATOM 5171 C CD1 . TYR B 1 496 ? 103.596 139.157 168.783 1.00 10.20 ? 496 TYR B CD1 1 
ATOM 5172 C CD2 . TYR B 1 496 ? 105.743 139.981 168.164 1.00 10.56 ? 496 TYR B CD2 1 
ATOM 5173 C CE1 . TYR B 1 496 ? 104.187 138.234 169.623 1.00 10.19 ? 496 TYR B CE1 1 
ATOM 5174 C CE2 . TYR B 1 496 ? 106.342 139.060 169.001 1.00 9.25  ? 496 TYR B CE2 1 
ATOM 5175 C CZ  . TYR B 1 496 ? 105.560 138.189 169.728 1.00 11.48 ? 496 TYR B CZ  1 
ATOM 5176 O OH  . TYR B 1 496 ? 106.152 137.271 170.562 1.00 14.44 ? 496 TYR B OH  1 
ATOM 5177 N N   . SER B 1 497 ? 105.000 143.519 168.690 1.00 6.80  ? 497 SER B N   1 
ATOM 5178 C CA  . SER B 1 497 ? 105.821 144.067 169.765 1.00 8.02  ? 497 SER B CA  1 
ATOM 5179 C C   . SER B 1 497 ? 105.058 145.027 170.667 1.00 10.46 ? 497 SER B C   1 
ATOM 5180 O O   . SER B 1 497 ? 105.280 145.023 171.882 1.00 9.24  ? 497 SER B O   1 
ATOM 5181 C CB  . SER B 1 497 ? 107.055 144.771 169.199 1.00 5.19  ? 497 SER B CB  1 
ATOM 5182 O OG  . SER B 1 497 ? 108.111 143.845 169.036 1.00 12.76 ? 497 SER B OG  1 
ATOM 5183 N N   . THR B 1 498 ? 104.171 145.852 170.109 1.00 6.05  ? 498 THR B N   1 
ATOM 5184 C CA  . THR B 1 498 ? 103.367 146.729 170.954 1.00 6.52  ? 498 THR B CA  1 
ATOM 5185 C C   . THR B 1 498 ? 102.438 145.929 171.864 1.00 10.80 ? 498 THR B C   1 
ATOM 5186 O O   . THR B 1 498 ? 102.391 146.170 173.079 1.00 13.22 ? 498 THR B O   1 
ATOM 5187 C CB  . THR B 1 498 ? 102.565 147.702 170.089 1.00 6.30  ? 498 THR B CB  1 
ATOM 5188 O OG1 . THR B 1 498 ? 103.428 148.744 169.617 1.00 10.84 ? 498 THR B OG1 1 
ATOM 5189 C CG2 . THR B 1 498 ? 101.427 148.322 170.888 1.00 7.41  ? 498 THR B CG2 1 
ATOM 5190 N N   . HIS B 1 499 ? 101.721 144.949 171.303 1.00 9.25  ? 499 HIS B N   1 
ATOM 5191 C CA  . HIS B 1 499 ? 100.801 144.115 172.068 1.00 6.47  ? 499 HIS B CA  1 
ATOM 5192 C C   . HIS B 1 499 ? 101.517 143.042 172.879 1.00 10.21 ? 499 HIS B C   1 
ATOM 5193 O O   . HIS B 1 499 ? 100.861 142.182 173.482 1.00 12.26 ? 499 HIS B O   1 
ATOM 5194 C CB  . HIS B 1 499 ? 99.764  143.482 171.140 1.00 7.32  ? 499 HIS B CB  1 
ATOM 5195 C CG  . HIS B 1 499 ? 98.758  144.453 170.606 1.00 5.52  ? 499 HIS B CG  1 
ATOM 5196 N ND1 . HIS B 1 499 ? 99.114  145.637 169.997 1.00 11.81 ? 499 HIS B ND1 1 
ATOM 5197 C CD2 . HIS B 1 499 ? 97.404  144.418 170.596 1.00 6.91  ? 499 HIS B CD2 1 
ATOM 5198 C CE1 . HIS B 1 499 ? 98.024  146.287 169.632 1.00 11.39 ? 499 HIS B CE1 1 
ATOM 5199 N NE2 . HIS B 1 499 ? 96.973  145.569 169.983 1.00 11.75 ? 499 HIS B NE2 1 
ATOM 5200 N N   . LYS B 1 500 ? 102.844 143.066 172.902 1.00 10.15 ? 500 LYS B N   1 
ATOM 5201 C CA  . LYS B 1 500 ? 103.597 142.217 173.814 1.00 8.73  ? 500 LYS B CA  1 
ATOM 5202 C C   . LYS B 1 500 ? 104.334 143.026 174.869 1.00 12.41 ? 500 LYS B C   1 
ATOM 5203 O O   . LYS B 1 500 ? 104.603 142.493 175.949 1.00 17.20 ? 500 LYS B O   1 
ATOM 5204 C CB  . LYS B 1 500 ? 104.586 141.341 173.021 1.00 10.86 ? 500 LYS B CB  1 
ATOM 5205 C CG  . LYS B 1 500 ? 105.387 140.352 173.856 1.00 7.59  ? 500 LYS B CG  1 
ATOM 5206 C CD  . LYS B 1 500 ? 106.297 139.501 172.989 1.00 7.80  ? 500 LYS B CD  1 
ATOM 5207 C CE  . LYS B 1 500 ? 107.111 138.534 173.833 1.00 11.56 ? 500 LYS B CE  1 
ATOM 5208 N NZ  . LYS B 1 500 ? 108.011 137.689 173.000 1.00 11.41 ? 500 LYS B NZ  1 
ATOM 5209 N N   . GLU B 1 501 ? 104.661 144.289 174.603 1.00 11.68 ? 501 GLU B N   1 
ATOM 5210 C CA  . GLU B 1 501 ? 105.152 145.207 175.618 1.00 9.57  ? 501 GLU B CA  1 
ATOM 5211 C C   . GLU B 1 501 ? 104.046 145.794 176.480 1.00 11.03 ? 501 GLU B C   1 
ATOM 5212 O O   . GLU B 1 501 ? 104.322 146.227 177.600 1.00 16.51 ? 501 GLU B O   1 
ATOM 5213 C CB  . GLU B 1 501 ? 105.940 146.353 174.968 1.00 9.72  ? 501 GLU B CB  1 
ATOM 5214 C CG  . GLU B 1 501 ? 105.089 147.544 174.548 1.00 9.03  ? 501 GLU B CG  1 
ATOM 5215 C CD  . GLU B 1 501 ? 105.909 148.671 173.950 1.00 10.90 ? 501 GLU B CD  1 
ATOM 5216 O OE1 . GLU B 1 501 ? 106.515 148.463 172.878 1.00 12.37 ? 501 GLU B OE1 1 
ATOM 5217 O OE2 . GLU B 1 501 ? 105.944 149.765 174.550 1.00 8.95  ? 501 GLU B OE2 1 
ATOM 5218 N N   . ARG B 1 502 ? 102.804 145.820 175.991 1.00 10.78 ? 502 ARG B N   1 
ATOM 5219 C CA  . ARG B 1 502 ? 101.701 146.309 176.809 1.00 8.03  ? 502 ARG B CA  1 
ATOM 5220 C C   . ARG B 1 502 ? 101.092 145.227 177.690 1.00 9.81  ? 502 ARG B C   1 
ATOM 5221 O O   . ARG B 1 502 ? 100.651 145.526 178.806 1.00 15.43 ? 502 ARG B O   1 
ATOM 5222 C CB  . ARG B 1 502 ? 100.610 146.922 175.929 1.00 9.36  ? 502 ARG B CB  1 
ATOM 5223 C CG  . ARG B 1 502 ? 100.555 148.441 176.000 1.00 9.52  ? 502 ARG B CG  1 
ATOM 5224 C CD  . ARG B 1 502 ? 99.234  148.986 175.480 1.00 10.51 ? 502 ARG B CD  1 
ATOM 5225 N NE  . ARG B 1 502 ? 98.909  148.487 174.149 1.00 14.15 ? 502 ARG B NE  1 
ATOM 5226 C CZ  . ARG B 1 502 ? 97.931  147.631 173.889 1.00 11.31 ? 502 ARG B CZ  1 
ATOM 5227 N NH1 . ARG B 1 502 ? 97.165  147.144 174.851 1.00 14.23 ? 502 ARG B NH1 1 
ATOM 5228 N NH2 . ARG B 1 502 ? 97.717  147.253 172.632 1.00 9.56  ? 502 ARG B NH2 1 
ATOM 5229 N N   . GLY B 1 503 ? 101.055 143.982 177.222 1.00 11.66 ? 503 GLY B N   1 
ATOM 5230 C CA  . GLY B 1 503 ? 100.488 142.904 178.009 1.00 8.33  ? 503 GLY B CA  1 
ATOM 5231 C C   . GLY B 1 503 ? 99.169  142.390 177.469 1.00 13.10 ? 503 GLY B C   1 
ATOM 5232 O O   . GLY B 1 503 ? 98.527  141.536 178.089 1.00 9.03  ? 503 GLY B O   1 
ATOM 5233 N N   . HIS B 1 504 ? 98.754  142.909 176.314 1.00 12.82 ? 504 HIS B N   1 
ATOM 5234 C CA  . HIS B 1 504 ? 97.492  142.523 175.693 1.00 9.19  ? 504 HIS B CA  1 
ATOM 5235 C C   . HIS B 1 504 ? 97.463  141.037 175.363 1.00 12.57 ? 504 HIS B C   1 
ATOM 5236 O O   . HIS B 1 504 ? 98.509  140.431 175.109 1.00 9.99  ? 504 HIS B O   1 
ATOM 5237 C CB  . HIS B 1 504 ? 97.251  143.347 174.427 1.00 9.77  ? 504 HIS B CB  1 
ATOM 5238 C CG  . HIS B 1 504 ? 95.827  143.766 174.238 1.00 12.09 ? 504 HIS B CG  1 
ATOM 5239 N ND1 . HIS B 1 504 ? 94.980  143.143 173.348 1.00 13.32 ? 504 HIS B ND1 1 
ATOM 5240 C CD2 . HIS B 1 504 ? 95.101  144.748 174.824 1.00 11.74 ? 504 HIS B CD2 1 
ATOM 5241 C CE1 . HIS B 1 504 ? 93.793  143.722 173.393 1.00 11.50 ? 504 HIS B CE1 1 
ATOM 5242 N NE2 . HIS B 1 504 ? 93.840  144.699 174.280 1.00 12.61 ? 504 HIS B NE2 1 
ATOM 5243 N N   . SER B 1 505 ? 96.271  140.440 175.373 1.00 11.30 ? 505 SER B N   1 
ATOM 5244 C CA  . SER B 1 505 ? 96.101  139.034 175.035 1.00 6.63  ? 505 SER B CA  1 
ATOM 5245 C C   . SER B 1 505 ? 95.979  138.788 173.537 1.00 11.17 ? 505 SER B C   1 
ATOM 5246 O O   . SER B 1 505 ? 95.969  137.627 173.115 1.00 14.01 ? 505 SER B O   1 
ATOM 5247 C CB  . SER B 1 505 ? 94.865  138.463 175.744 1.00 11.24 ? 505 SER B CB  1 
ATOM 5248 O OG  . SER B 1 505 ? 93.706  138.605 174.942 1.00 8.49  ? 505 SER B OG  1 
ATOM 5249 N N   . ASP B 1 506 ? 95.886  139.845 172.728 1.00 11.53 ? 506 ASP B N   1 
ATOM 5250 C CA  . ASP B 1 506 ? 95.817  139.709 171.278 1.00 9.81  ? 506 ASP B CA  1 
ATOM 5251 C C   . ASP B 1 506 ? 97.188  139.573 170.631 1.00 10.01 ? 506 ASP B C   1 
ATOM 5252 O O   . ASP B 1 506 ? 97.304  139.784 169.419 1.00 13.61 ? 506 ASP B O   1 
ATOM 5253 C CB  . ASP B 1 506 ? 95.081  140.908 170.675 1.00 9.18  ? 506 ASP B CB  1 
ATOM 5254 C CG  . ASP B 1 506 ? 93.675  140.563 170.227 1.00 11.74 ? 506 ASP B CG  1 
ATOM 5255 O OD1 . ASP B 1 506 ? 93.432  139.389 169.878 1.00 15.26 ? 506 ASP B OD1 1 
ATOM 5256 O OD2 . ASP B 1 506 ? 92.813  141.467 170.223 1.00 9.24  ? 506 ASP B OD2 1 
ATOM 5257 N N   . THR B 1 507 ? 98.223  139.241 171.405 1.00 11.93 ? 507 THR B N   1 
ATOM 5258 C CA  . THR B 1 507 ? 99.571  139.147 170.854 1.00 8.24  ? 507 THR B CA  1 
ATOM 5259 C C   . THR B 1 507 ? 99.700  137.969 169.895 1.00 11.35 ? 507 THR B C   1 
ATOM 5260 O O   . THR B 1 507 ? 100.446 138.033 168.912 1.00 17.57 ? 507 THR B O   1 
ATOM 5261 C CB  . THR B 1 507 ? 100.590 139.024 171.987 1.00 7.89  ? 507 THR B CB  1 
ATOM 5262 O OG1 . THR B 1 507 ? 100.522 140.187 172.819 1.00 15.72 ? 507 THR B OG1 1 
ATOM 5263 C CG2 . THR B 1 507 ? 101.995 138.908 171.422 1.00 11.49 ? 507 THR B CG2 1 
ATOM 5264 N N   . MET B 1 508 ? 98.985  136.877 170.175 1.00 11.35 ? 508 MET B N   1 
ATOM 5265 C CA  . MET B 1 508 ? 99.153  135.656 169.392 1.00 10.85 ? 508 MET B CA  1 
ATOM 5266 C C   . MET B 1 508 ? 98.714  135.851 167.945 1.00 8.88  ? 508 MET B C   1 
ATOM 5267 O O   . MET B 1 508 ? 99.354  135.344 167.018 1.00 17.62 ? 508 MET B O   1 
ATOM 5268 C CB  . MET B 1 508 ? 98.382  134.506 170.041 1.00 12.80 ? 508 MET B CB  1 
ATOM 5269 C CG  . MET B 1 508 ? 99.180  133.681 171.053 1.00 8.80  ? 508 MET B CG  1 
ATOM 5270 S SD  . MET B 1 508 ? 100.882 133.304 170.574 1.00 26.65 ? 508 MET B SD  1 
ATOM 5271 C CE  . MET B 1 508 ? 101.797 134.606 171.403 1.00 12.20 ? 508 MET B CE  1 
ATOM 5272 N N   . VAL B 1 509 ? 97.613  136.575 167.730 1.00 8.56  ? 509 VAL B N   1 
ATOM 5273 C CA  . VAL B 1 509 ? 97.129  136.787 166.366 1.00 7.56  ? 509 VAL B CA  1 
ATOM 5274 C C   . VAL B 1 509 ? 98.114  137.658 165.588 1.00 11.53 ? 509 VAL B C   1 
ATOM 5275 O O   . VAL B 1 509 ? 98.424  137.393 164.420 1.00 12.21 ? 509 VAL B O   1 
ATOM 5276 C CB  . VAL B 1 509 ? 95.704  137.374 166.377 1.00 6.74  ? 509 VAL B CB  1 
ATOM 5277 C CG1 . VAL B 1 509 ? 95.677  138.828 166.838 1.00 7.99  ? 509 VAL B CG1 1 
ATOM 5278 C CG2 . VAL B 1 509 ? 95.056  137.232 165.010 1.00 7.90  ? 509 VAL B CG2 1 
ATOM 5279 N N   . PHE B 1 510 ? 98.646  138.697 166.239 1.00 13.98 ? 510 PHE B N   1 
ATOM 5280 C CA  . PHE B 1 510 ? 99.633  139.547 165.585 1.00 7.15  ? 510 PHE B CA  1 
ATOM 5281 C C   . PHE B 1 510 ? 100.923 138.789 165.316 1.00 7.48  ? 510 PHE B C   1 
ATOM 5282 O O   . PHE B 1 510 ? 101.653 139.118 164.375 1.00 15.00 ? 510 PHE B O   1 
ATOM 5283 C CB  . PHE B 1 510 ? 99.907  140.787 166.437 1.00 6.76  ? 510 PHE B CB  1 
ATOM 5284 C CG  . PHE B 1 510 ? 98.855  141.852 166.315 1.00 7.51  ? 510 PHE B CG  1 
ATOM 5285 C CD1 . PHE B 1 510 ? 98.177  142.038 165.122 1.00 8.28  ? 510 PHE B CD1 1 
ATOM 5286 C CD2 . PHE B 1 510 ? 98.549  142.673 167.388 1.00 10.16 ? 510 PHE B CD2 1 
ATOM 5287 C CE1 . PHE B 1 510 ? 97.211  143.018 165.002 1.00 8.10  ? 510 PHE B CE1 1 
ATOM 5288 C CE2 . PHE B 1 510 ? 97.583  143.656 167.274 1.00 7.33  ? 510 PHE B CE2 1 
ATOM 5289 C CZ  . PHE B 1 510 ? 96.914  143.828 166.078 1.00 7.96  ? 510 PHE B CZ  1 
ATOM 5290 N N   . PHE B 1 511 ? 101.219 137.778 166.132 1.00 7.12  ? 511 PHE B N   1 
ATOM 5291 C CA  . PHE B 1 511 ? 102.378 136.927 165.899 1.00 7.84  ? 511 PHE B CA  1 
ATOM 5292 C C   . PHE B 1 511 ? 102.149 135.998 164.712 1.00 11.06 ? 511 PHE B C   1 
ATOM 5293 O O   . PHE B 1 511 ? 103.055 135.785 163.898 1.00 12.36 ? 511 PHE B O   1 
ATOM 5294 C CB  . PHE B 1 511 ? 102.684 136.130 167.169 1.00 8.05  ? 511 PHE B CB  1 
ATOM 5295 C CG  . PHE B 1 511 ? 103.876 135.226 167.058 1.00 8.79  ? 511 PHE B CG  1 
ATOM 5296 C CD1 . PHE B 1 511 ? 105.156 135.728 167.210 1.00 9.08  ? 511 PHE B CD1 1 
ATOM 5297 C CD2 . PHE B 1 511 ? 103.716 133.870 166.831 1.00 10.74 ? 511 PHE B CD2 1 
ATOM 5298 C CE1 . PHE B 1 511 ? 106.255 134.898 167.121 1.00 8.46  ? 511 PHE B CE1 1 
ATOM 5299 C CE2 . PHE B 1 511 ? 104.810 133.036 166.740 1.00 6.54  ? 511 PHE B CE2 1 
ATOM 5300 C CZ  . PHE B 1 511 ? 106.082 133.551 166.885 1.00 5.88  ? 511 PHE B CZ  1 
ATOM 5301 N N   . TYR B 1 512 ? 100.937 135.453 164.589 1.00 11.27 ? 512 TYR B N   1 
ATOM 5302 C CA  . TYR B 1 512 ? 100.655 134.512 163.508 1.00 7.53  ? 512 TYR B CA  1 
ATOM 5303 C C   . TYR B 1 512 ? 100.589 135.211 162.154 1.00 5.92  ? 512 TYR B C   1 
ATOM 5304 O O   . TYR B 1 512 ? 101.129 134.699 161.163 1.00 10.37 ? 512 TYR B O   1 
ATOM 5305 C CB  . TYR B 1 512 ? 99.362  133.751 163.795 1.00 9.45  ? 512 TYR B CB  1 
ATOM 5306 C CG  . TYR B 1 512 ? 99.521  132.687 164.858 1.00 8.11  ? 512 TYR B CG  1 
ATOM 5307 C CD1 . TYR B 1 512 ? 100.636 131.861 164.872 1.00 8.46  ? 512 TYR B CD1 1 
ATOM 5308 C CD2 . TYR B 1 512 ? 98.558  132.506 165.842 1.00 10.86 ? 512 TYR B CD2 1 
ATOM 5309 C CE1 . TYR B 1 512 ? 100.792 130.887 165.838 1.00 9.10  ? 512 TYR B CE1 1 
ATOM 5310 C CE2 . TYR B 1 512 ? 98.705  131.532 166.814 1.00 11.70 ? 512 TYR B CE2 1 
ATOM 5311 C CZ  . TYR B 1 512 ? 99.824  130.726 166.807 1.00 11.39 ? 512 TYR B CZ  1 
ATOM 5312 O OH  . TYR B 1 512 ? 99.977  129.755 167.770 1.00 14.97 ? 512 TYR B OH  1 
ATOM 5313 N N   . LEU B 1 513 ? 99.930  136.375 162.081 1.00 7.99  ? 513 LEU B N   1 
ATOM 5314 C CA  . LEU B 1 513 ? 99.996  137.145 160.839 1.00 8.12  ? 513 LEU B CA  1 
ATOM 5315 C C   . LEU B 1 513 ? 101.424 137.561 160.509 1.00 7.49  ? 513 LEU B C   1 
ATOM 5316 O O   . LEU B 1 513 ? 101.818 137.554 159.336 1.00 6.28  ? 513 LEU B O   1 
ATOM 5317 C CB  . LEU B 1 513 ? 99.065  138.363 160.858 1.00 7.19  ? 513 LEU B CB  1 
ATOM 5318 C CG  . LEU B 1 513 ? 97.543  138.189 160.740 1.00 7.16  ? 513 LEU B CG  1 
ATOM 5319 C CD1 . LEU B 1 513 ? 97.234  137.269 159.564 1.00 4.85  ? 513 LEU B CD1 1 
ATOM 5320 C CD2 . LEU B 1 513 ? 96.848  137.696 161.975 1.00 7.83  ? 513 LEU B CD2 1 
ATOM 5321 N N   . TRP B 1 514 ? 102.224 137.909 161.520 1.00 7.85  ? 514 TRP B N   1 
ATOM 5322 C CA  . TRP B 1 514 ? 103.617 138.236 161.231 1.00 3.61  ? 514 TRP B CA  1 
ATOM 5323 C C   . TRP B 1 514 ? 104.352 137.038 160.649 1.00 7.45  ? 514 TRP B C   1 
ATOM 5324 O O   . TRP B 1 514 ? 105.139 137.186 159.711 1.00 13.44 ? 514 TRP B O   1 
ATOM 5325 C CB  . TRP B 1 514 ? 104.351 138.733 162.474 1.00 3.66  ? 514 TRP B CB  1 
ATOM 5326 C CG  . TRP B 1 514 ? 105.820 138.854 162.194 1.00 3.42  ? 514 TRP B CG  1 
ATOM 5327 C CD1 . TRP B 1 514 ? 106.430 139.819 161.448 1.00 1.79  ? 514 TRP B CD1 1 
ATOM 5328 C CD2 . TRP B 1 514 ? 106.856 137.953 162.606 1.00 7.70  ? 514 TRP B CD2 1 
ATOM 5329 N NE1 . TRP B 1 514 ? 107.780 139.589 161.387 1.00 1.85  ? 514 TRP B NE1 1 
ATOM 5330 C CE2 . TRP B 1 514 ? 108.069 138.450 162.089 1.00 5.27  ? 514 TRP B CE2 1 
ATOM 5331 C CE3 . TRP B 1 514 ? 106.878 136.783 163.370 1.00 5.95  ? 514 TRP B CE3 1 
ATOM 5332 C CZ2 . TRP B 1 514 ? 109.290 137.818 162.313 1.00 7.05  ? 514 TRP B CZ2 1 
ATOM 5333 C CZ3 . TRP B 1 514 ? 108.091 136.159 163.591 1.00 5.50  ? 514 TRP B CZ3 1 
ATOM 5334 C CH2 . TRP B 1 514 ? 109.279 136.676 163.063 1.00 7.54  ? 514 TRP B CH2 1 
ATOM 5335 N N   . ILE B 1 515 ? 104.117 135.843 161.194 1.00 4.94  ? 515 ILE B N   1 
ATOM 5336 C CA  . ILE B 1 515 ? 104.814 134.654 160.703 1.00 5.53  ? 515 ILE B CA  1 
ATOM 5337 C C   . ILE B 1 515 ? 104.414 134.356 159.261 1.00 5.28  ? 515 ILE B C   1 
ATOM 5338 O O   . ILE B 1 515 ? 105.268 134.103 158.398 1.00 5.52  ? 515 ILE B O   1 
ATOM 5339 C CB  . ILE B 1 515 ? 104.544 133.452 161.626 1.00 6.29  ? 515 ILE B CB  1 
ATOM 5340 C CG1 . ILE B 1 515 ? 105.589 133.392 162.741 1.00 9.14  ? 515 ILE B CG1 1 
ATOM 5341 C CG2 . ILE B 1 515 ? 104.553 132.150 160.838 1.00 5.49  ? 515 ILE B CG2 1 
ATOM 5342 C CD1 . ILE B 1 515 ? 106.982 133.075 162.248 1.00 5.50  ? 515 ILE B CD1 1 
ATOM 5343 N N   . VAL B 1 516 ? 103.109 134.389 158.976 1.00 7.38  ? 516 VAL B N   1 
ATOM 5344 C CA  . VAL B 1 516 ? 102.668 134.042 157.628 1.00 3.25  ? 516 VAL B CA  1 
ATOM 5345 C C   . VAL B 1 516 ? 103.151 135.085 156.628 1.00 4.73  ? 516 VAL B C   1 
ATOM 5346 O O   . VAL B 1 516 ? 103.554 134.748 155.510 1.00 10.05 ? 516 VAL B O   1 
ATOM 5347 C CB  . VAL B 1 516 ? 101.138 133.851 157.569 1.00 5.28  ? 516 VAL B CB  1 
ATOM 5348 C CG1 . VAL B 1 516 ? 100.408 135.084 158.040 1.00 4.71  ? 516 VAL B CG1 1 
ATOM 5349 C CG2 . VAL B 1 516 ? 100.701 133.480 156.160 1.00 4.07  ? 516 VAL B CG2 1 
ATOM 5350 N N   . PHE B 1 517 ? 103.162 136.364 157.019 1.00 5.74  ? 517 PHE B N   1 
ATOM 5351 C CA  . PHE B 1 517 ? 103.633 137.388 156.097 1.00 5.17  ? 517 PHE B CA  1 
ATOM 5352 C C   . PHE B 1 517 ? 105.149 137.382 155.956 1.00 4.35  ? 517 PHE B C   1 
ATOM 5353 O O   . PHE B 1 517 ? 105.662 137.740 154.895 1.00 6.47  ? 517 PHE B O   1 
ATOM 5354 C CB  . PHE B 1 517 ? 103.126 138.761 156.534 1.00 5.21  ? 517 PHE B CB  1 
ATOM 5355 C CG  . PHE B 1 517 ? 101.804 139.124 155.927 1.00 5.89  ? 517 PHE B CG  1 
ATOM 5356 C CD1 . PHE B 1 517 ? 101.717 139.474 154.591 1.00 2.99  ? 517 PHE B CD1 1 
ATOM 5357 C CD2 . PHE B 1 517 ? 100.642 139.077 156.678 1.00 6.35  ? 517 PHE B CD2 1 
ATOM 5358 C CE1 . PHE B 1 517 ? 100.503 139.796 154.022 1.00 7.30  ? 517 PHE B CE1 1 
ATOM 5359 C CE2 . PHE B 1 517 ? 99.423  139.397 156.113 1.00 6.68  ? 517 PHE B CE2 1 
ATOM 5360 C CZ  . PHE B 1 517 ? 99.354  139.758 154.784 1.00 4.82  ? 517 PHE B CZ  1 
ATOM 5361 N N   . TYR B 1 518 ? 105.880 136.959 156.989 1.00 5.25  ? 518 TYR B N   1 
ATOM 5362 C CA  . TYR B 1 518 ? 107.315 136.751 156.845 1.00 3.39  ? 518 TYR B CA  1 
ATOM 5363 C C   . TYR B 1 518 ? 107.599 135.657 155.828 1.00 3.34  ? 518 TYR B C   1 
ATOM 5364 O O   . TYR B 1 518 ? 108.460 135.817 154.952 1.00 6.92  ? 518 TYR B O   1 
ATOM 5365 C CB  . TYR B 1 518 ? 107.925 136.413 158.210 1.00 3.12  ? 518 TYR B CB  1 
ATOM 5366 C CG  . TYR B 1 518 ? 109.286 135.749 158.164 1.00 4.57  ? 518 TYR B CG  1 
ATOM 5367 C CD1 . TYR B 1 518 ? 109.409 134.366 158.080 1.00 5.00  ? 518 TYR B CD1 1 
ATOM 5368 C CD2 . TYR B 1 518 ? 110.448 136.504 158.220 1.00 2.25  ? 518 TYR B CD2 1 
ATOM 5369 C CE1 . TYR B 1 518 ? 110.648 133.760 158.039 1.00 0.00  ? 518 TYR B CE1 1 
ATOM 5370 C CE2 . TYR B 1 518 ? 111.691 135.904 158.182 1.00 2.86  ? 518 TYR B CE2 1 
ATOM 5371 C CZ  . TYR B 1 518 ? 111.786 134.535 158.089 1.00 1.65  ? 518 TYR B CZ  1 
ATOM 5372 O OH  . TYR B 1 518 ? 113.026 133.942 158.051 1.00 0.03  ? 518 TYR B OH  1 
ATOM 5373 N N   . ILE B 1 519 ? 106.866 134.545 155.918 1.00 3.38  ? 519 ILE B N   1 
ATOM 5374 C CA  . ILE B 1 519 ? 107.031 133.467 154.946 1.00 4.53  ? 519 ILE B CA  1 
ATOM 5375 C C   . ILE B 1 519 ? 106.669 133.952 153.547 1.00 3.35  ? 519 ILE B C   1 
ATOM 5376 O O   . ILE B 1 519 ? 107.377 133.669 152.570 1.00 5.26  ? 519 ILE B O   1 
ATOM 5377 C CB  . ILE B 1 519 ? 106.193 132.244 155.361 1.00 5.28  ? 519 ILE B CB  1 
ATOM 5378 C CG1 . ILE B 1 519 ? 106.955 131.400 156.385 1.00 5.13  ? 519 ILE B CG1 1 
ATOM 5379 C CG2 . ILE B 1 519 ? 105.822 131.403 154.149 1.00 0.37  ? 519 ILE B CG2 1 
ATOM 5380 C CD1 . ILE B 1 519 ? 106.083 130.425 157.139 1.00 3.67  ? 519 ILE B CD1 1 
ATOM 5381 N N   . ILE B 1 520 ? 105.569 134.700 153.431 1.00 1.26  ? 520 ILE B N   1 
ATOM 5382 C CA  . ILE B 1 520 ? 105.125 135.190 152.129 1.00 3.05  ? 520 ILE B CA  1 
ATOM 5383 C C   . ILE B 1 520 ? 106.166 136.127 151.528 1.00 4.65  ? 520 ILE B C   1 
ATOM 5384 O O   . ILE B 1 520 ? 106.506 136.022 150.347 1.00 4.29  ? 520 ILE B O   1 
ATOM 5385 C CB  . ILE B 1 520 ? 103.752 135.874 152.252 1.00 6.56  ? 520 ILE B CB  1 
ATOM 5386 C CG1 . ILE B 1 520 ? 102.639 134.826 152.324 1.00 5.92  ? 520 ILE B CG1 1 
ATOM 5387 C CG2 . ILE B 1 520 ? 103.514 136.814 151.083 1.00 3.62  ? 520 ILE B CG2 1 
ATOM 5388 C CD1 . ILE B 1 520 ? 101.246 135.415 152.339 1.00 3.24  ? 520 ILE B CD1 1 
ATOM 5389 N N   . SER B 1 521 ? 106.694 137.051 152.334 1.00 4.85  ? 521 SER B N   1 
ATOM 5390 C CA  . SER B 1 521 ? 107.691 137.995 151.840 1.00 4.05  ? 521 SER B CA  1 
ATOM 5391 C C   . SER B 1 521 ? 108.962 137.277 151.404 1.00 3.10  ? 521 SER B C   1 
ATOM 5392 O O   . SER B 1 521 ? 109.509 137.557 150.329 1.00 0.16  ? 521 SER B O   1 
ATOM 5393 C CB  . SER B 1 521 ? 107.998 139.035 152.920 1.00 3.33  ? 521 SER B CB  1 
ATOM 5394 O OG  . SER B 1 521 ? 108.916 140.006 152.453 1.00 7.72  ? 521 SER B OG  1 
ATOM 5395 N N   . SER B 1 522 ? 109.440 136.335 152.223 1.00 1.21  ? 522 SER B N   1 
ATOM 5396 C CA  . SER B 1 522 ? 110.656 135.605 151.879 1.00 1.43  ? 522 SER B CA  1 
ATOM 5397 C C   . SER B 1 522 ? 110.482 134.823 150.582 1.00 2.90  ? 522 SER B C   1 
ATOM 5398 O O   . SER B 1 522 ? 111.318 134.912 149.674 1.00 6.23  ? 522 SER B O   1 
ATOM 5399 C CB  . SER B 1 522 ? 111.047 134.669 153.023 1.00 2.72  ? 522 SER B CB  1 
ATOM 5400 O OG  . SER B 1 522 ? 110.741 135.240 154.281 1.00 6.44  ? 522 SER B OG  1 
ATOM 5401 N N   . CYS B 1 523 ? 109.389 134.060 150.471 1.00 1.71  ? 523 CYS B N   1 
ATOM 5402 C CA  . CYS B 1 523 ? 109.162 133.268 149.266 1.00 3.99  ? 523 CYS B CA  1 
ATOM 5403 C C   . CYS B 1 523 ? 108.951 134.156 148.045 1.00 3.14  ? 523 CYS B C   1 
ATOM 5404 O O   . CYS B 1 523 ? 109.466 133.859 146.962 1.00 4.79  ? 523 CYS B O   1 
ATOM 5405 C CB  . CYS B 1 523 ? 107.968 132.336 149.469 1.00 5.88  ? 523 CYS B CB  1 
ATOM 5406 S SG  . CYS B 1 523 ? 108.303 130.923 150.549 1.00 13.16 ? 523 CYS B SG  1 
ATOM 5407 N N   . TYR B 1 524 ? 108.200 135.248 148.202 1.00 1.47  ? 524 TYR B N   1 
ATOM 5408 C CA  . TYR B 1 524 ? 107.945 136.175 147.105 1.00 0.11  ? 524 TYR B CA  1 
ATOM 5409 C C   . TYR B 1 524 ? 109.246 136.752 146.564 1.00 0.85  ? 524 TYR B C   1 
ATOM 5410 O O   . TYR B 1 524 ? 109.503 136.711 145.353 1.00 2.35  ? 524 TYR B O   1 
ATOM 5411 C CB  . TYR B 1 524 ? 107.022 137.286 147.609 1.00 2.41  ? 524 TYR B CB  1 
ATOM 5412 C CG  . TYR B 1 524 ? 106.100 137.930 146.596 1.00 2.68  ? 524 TYR B CG  1 
ATOM 5413 C CD1 . TYR B 1 524 ? 106.496 138.144 145.284 1.00 2.79  ? 524 TYR B CD1 1 
ATOM 5414 C CD2 . TYR B 1 524 ? 104.831 138.350 146.972 1.00 2.12  ? 524 TYR B CD2 1 
ATOM 5415 C CE1 . TYR B 1 524 ? 105.647 138.746 144.374 1.00 1.01  ? 524 TYR B CE1 1 
ATOM 5416 C CE2 . TYR B 1 524 ? 103.980 138.949 146.076 1.00 0.00  ? 524 TYR B CE2 1 
ATOM 5417 C CZ  . TYR B 1 524 ? 104.388 139.145 144.778 1.00 1.40  ? 524 TYR B CZ  1 
ATOM 5418 O OH  . TYR B 1 524 ? 103.531 139.744 143.889 1.00 5.32  ? 524 TYR B OH  1 
ATOM 5419 N N   . THR B 1 525 ? 110.092 137.281 147.453 1.00 0.00  ? 525 THR B N   1 
ATOM 5420 C CA  . THR B 1 525 ? 111.341 137.886 147.001 1.00 0.77  ? 525 THR B CA  1 
ATOM 5421 C C   . THR B 1 525 ? 112.293 136.842 146.430 1.00 1.79  ? 525 THR B C   1 
ATOM 5422 O O   . THR B 1 525 ? 112.981 137.109 145.440 1.00 3.37  ? 525 THR B O   1 
ATOM 5423 C CB  . THR B 1 525 ? 112.007 138.663 148.139 1.00 4.53  ? 525 THR B CB  1 
ATOM 5424 O OG1 . THR B 1 525 ? 112.052 137.857 149.322 1.00 4.28  ? 525 THR B OG1 1 
ATOM 5425 C CG2 . THR B 1 525 ? 111.241 139.943 148.425 1.00 0.00  ? 525 THR B CG2 1 
ATOM 5426 N N   . LEU B 1 526 ? 112.342 135.645 147.026 1.00 0.15  ? 526 LEU B N   1 
ATOM 5427 C CA  . LEU B 1 526 ? 113.217 134.598 146.502 1.00 0.61  ? 526 LEU B CA  1 
ATOM 5428 C C   . LEU B 1 526 ? 112.785 134.155 145.107 1.00 1.14  ? 526 LEU B C   1 
ATOM 5429 O O   . LEU B 1 526 ? 113.626 133.981 144.215 1.00 0.00  ? 526 LEU B O   1 
ATOM 5430 C CB  . LEU B 1 526 ? 113.238 133.410 147.463 1.00 0.62  ? 526 LEU B CB  1 
ATOM 5431 C CG  . LEU B 1 526 ? 114.000 132.151 147.044 1.00 0.98  ? 526 LEU B CG  1 
ATOM 5432 C CD1 . LEU B 1 526 ? 115.441 132.474 146.673 1.00 0.84  ? 526 LEU B CD1 1 
ATOM 5433 C CD2 . LEU B 1 526 ? 113.945 131.108 148.145 1.00 2.79  ? 526 LEU B CD2 1 
ATOM 5434 N N   . ILE B 1 527 ? 111.479 133.979 144.896 1.00 0.00  ? 527 ILE B N   1 
ATOM 5435 C CA  . ILE B 1 527 ? 110.990 133.548 143.592 1.00 0.00  ? 527 ILE B CA  1 
ATOM 5436 C C   . ILE B 1 527 ? 111.195 134.643 142.554 1.00 1.38  ? 527 ILE B C   1 
ATOM 5437 O O   . ILE B 1 527 ? 111.553 134.362 141.404 1.00 0.58  ? 527 ILE B O   1 
ATOM 5438 C CB  . ILE B 1 527 ? 109.517 133.112 143.693 1.00 0.13  ? 527 ILE B CB  1 
ATOM 5439 C CG1 . ILE B 1 527 ? 109.410 131.791 144.459 1.00 2.53  ? 527 ILE B CG1 1 
ATOM 5440 C CG2 . ILE B 1 527 ? 108.897 132.966 142.313 1.00 0.00  ? 527 ILE B CG2 1 
ATOM 5441 C CD1 . ILE B 1 527 ? 108.015 131.470 144.944 1.00 1.57  ? 527 ILE B CD1 1 
ATOM 5442 N N   . TRP B 1 528 ? 110.984 135.908 142.936 1.00 2.28  ? 528 TRP B N   1 
ATOM 5443 C CA  . TRP B 1 528 ? 111.252 137.002 142.008 1.00 0.37  ? 528 TRP B CA  1 
ATOM 5444 C C   . TRP B 1 528 ? 112.735 137.083 141.660 1.00 0.08  ? 528 TRP B C   1 
ATOM 5445 O O   . TRP B 1 528 ? 113.095 137.355 140.510 1.00 0.00  ? 528 TRP B O   1 
ATOM 5446 C CB  . TRP B 1 528 ? 110.759 138.329 142.587 1.00 0.59  ? 528 TRP B CB  1 
ATOM 5447 C CG  . TRP B 1 528 ? 110.666 139.418 141.558 1.00 1.83  ? 528 TRP B CG  1 
ATOM 5448 C CD1 . TRP B 1 528 ? 111.657 140.274 141.180 1.00 0.00  ? 528 TRP B CD1 1 
ATOM 5449 C CD2 . TRP B 1 528 ? 109.523 139.751 140.763 1.00 0.30  ? 528 TRP B CD2 1 
ATOM 5450 N NE1 . TRP B 1 528 ? 111.201 141.125 140.205 1.00 0.74  ? 528 TRP B NE1 1 
ATOM 5451 C CE2 . TRP B 1 528 ? 109.893 140.825 139.931 1.00 0.00  ? 528 TRP B CE2 1 
ATOM 5452 C CE3 . TRP B 1 528 ? 108.222 139.249 140.677 1.00 0.44  ? 528 TRP B CE3 1 
ATOM 5453 C CZ2 . TRP B 1 528 ? 109.010 141.404 139.023 1.00 0.00  ? 528 TRP B CZ2 1 
ATOM 5454 C CZ3 . TRP B 1 528 ? 107.347 139.826 139.776 1.00 2.19  ? 528 TRP B CZ3 1 
ATOM 5455 C CH2 . TRP B 1 528 ? 107.745 140.891 138.961 1.00 0.00  ? 528 TRP B CH2 1 
ATOM 5456 N N   . ASP B 1 529 ? 113.610 136.853 142.642 1.00 0.00  ? 529 ASP B N   1 
ATOM 5457 C CA  . ASP B 1 529 ? 115.044 136.824 142.374 1.00 0.00  ? 529 ASP B CA  1 
ATOM 5458 C C   . ASP B 1 529 ? 115.396 135.720 141.383 1.00 0.00  ? 529 ASP B C   1 
ATOM 5459 O O   . ASP B 1 529 ? 116.146 135.943 140.427 1.00 1.18  ? 529 ASP B O   1 
ATOM 5460 C CB  . ASP B 1 529 ? 115.817 136.621 143.678 1.00 0.00  ? 529 ASP B CB  1 
ATOM 5461 C CG  . ASP B 1 529 ? 115.983 137.900 144.474 1.00 0.62  ? 529 ASP B CG  1 
ATOM 5462 O OD1 . ASP B 1 529 ? 115.541 138.969 144.005 1.00 6.29  ? 529 ASP B OD1 1 
ATOM 5463 O OD2 . ASP B 1 529 ? 116.555 137.831 145.579 1.00 0.76  ? 529 ASP B OD2 1 
ATOM 5464 N N   . LEU B 1 530 ? 114.856 134.518 141.598 1.00 0.00  ? 530 LEU B N   1 
ATOM 5465 C CA  . LEU B 1 530 ? 115.280 133.366 140.808 1.00 0.00  ? 530 LEU B CA  1 
ATOM 5466 C C   . LEU B 1 530 ? 114.679 133.374 139.405 1.00 0.67  ? 530 LEU B C   1 
ATOM 5467 O O   . LEU B 1 530 ? 115.355 133.002 138.440 1.00 0.00  ? 530 LEU B O   1 
ATOM 5468 C CB  . LEU B 1 530 ? 114.916 132.072 141.536 1.00 0.00  ? 530 LEU B CB  1 
ATOM 5469 C CG  . LEU B 1 530 ? 115.657 131.793 142.848 1.00 1.59  ? 530 LEU B CG  1 
ATOM 5470 C CD1 . LEU B 1 530 ? 115.281 130.430 143.407 1.00 0.97  ? 530 LEU B CD1 1 
ATOM 5471 C CD2 . LEU B 1 530 ? 117.162 131.905 142.673 1.00 0.00  ? 530 LEU B CD2 1 
ATOM 5472 N N   . LYS B 1 531 ? 113.425 133.803 139.266 1.00 0.65  ? 531 LYS B N   1 
ATOM 5473 C CA  . LYS B 1 531 ? 112.707 133.680 138.003 1.00 0.00  ? 531 LYS B CA  1 
ATOM 5474 C C   . LYS B 1 531 ? 112.689 134.955 137.174 1.00 4.45  ? 531 LYS B C   1 
ATOM 5475 O O   . LYS B 1 531 ? 112.693 134.873 135.942 1.00 2.10  ? 531 LYS B O   1 
ATOM 5476 C CB  . LYS B 1 531 ? 111.262 133.237 138.255 1.00 1.01  ? 531 LYS B CB  1 
ATOM 5477 C CG  . LYS B 1 531 ? 111.026 131.752 138.060 1.00 5.85  ? 531 LYS B CG  1 
ATOM 5478 C CD  . LYS B 1 531 ? 110.675 131.435 136.614 1.00 1.73  ? 531 LYS B CD  1 
ATOM 5479 C CE  . LYS B 1 531 ? 110.656 129.939 136.369 1.00 4.88  ? 531 LYS B CE  1 
ATOM 5480 N NZ  . LYS B 1 531 ? 110.615 129.613 134.918 1.00 4.53  ? 531 LYS B NZ  1 
ATOM 5481 N N   . MET B 1 532 ? 112.651 136.129 137.801 1.00 4.96  ? 532 MET B N   1 
ATOM 5482 C CA  . MET B 1 532 ? 112.565 137.380 137.059 1.00 0.82  ? 532 MET B CA  1 
ATOM 5483 C C   . MET B 1 532 ? 113.895 138.122 136.990 1.00 1.34  ? 532 MET B C   1 
ATOM 5484 O O   . MET B 1 532 ? 114.330 138.501 135.901 1.00 6.19  ? 532 MET B O   1 
ATOM 5485 C CB  . MET B 1 532 ? 111.488 138.287 137.669 1.00 0.76  ? 532 MET B CB  1 
ATOM 5486 C CG  . MET B 1 532 ? 110.163 137.589 137.921 1.00 2.60  ? 532 MET B CG  1 
ATOM 5487 S SD  . MET B 1 532 ? 109.254 137.194 136.411 1.00 7.70  ? 532 MET B SD  1 
ATOM 5488 C CE  . MET B 1 532 ? 109.010 138.819 135.703 1.00 4.04  ? 532 MET B CE  1 
ATOM 5489 N N   . ASP B 1 533 ? 114.553 138.335 138.133 1.00 0.00  ? 533 ASP B N   1 
ATOM 5490 C CA  . ASP B 1 533 ? 115.798 139.099 138.141 1.00 0.00  ? 533 ASP B CA  1 
ATOM 5491 C C   . ASP B 1 533 ? 116.911 138.363 137.402 1.00 0.00  ? 533 ASP B C   1 
ATOM 5492 O O   . ASP B 1 533 ? 117.580 138.937 136.535 1.00 0.00  ? 533 ASP B O   1 
ATOM 5493 C CB  . ASP B 1 533 ? 116.223 139.401 139.580 1.00 0.00  ? 533 ASP B CB  1 
ATOM 5494 C CG  . ASP B 1 533 ? 115.341 140.441 140.249 1.00 0.00  ? 533 ASP B CG  1 
ATOM 5495 O OD1 . ASP B 1 533 ? 115.089 141.501 139.640 1.00 3.36  ? 533 ASP B OD1 1 
ATOM 5496 O OD2 . ASP B 1 533 ? 114.906 140.201 141.393 1.00 0.00  ? 533 ASP B OD2 1 
ATOM 5497 N N   . TRP B 1 534 ? 117.102 137.088 137.759 1.00 3.28  ? 534 TRP B N   1 
ATOM 5498 C CA  . TRP B 1 534 ? 118.186 136.279 137.145 1.00 0.00  ? 534 TRP B CA  1 
ATOM 5499 C C   . TRP B 1 534 ? 117.621 135.459 135.986 1.00 0.65  ? 534 TRP B C   1 
ATOM 5500 O O   . TRP B 1 534 ? 118.416 135.020 135.126 1.00 8.99  ? 534 TRP B O   1 
ATOM 5501 C CB  . TRP B 1 534 ? 118.821 135.365 138.201 1.00 0.00  ? 534 TRP B CB  1 
ATOM 5502 C CG  . TRP B 1 534 ? 119.409 136.086 139.386 1.00 1.18  ? 534 TRP B CG  1 
ATOM 5503 C CD1 . TRP B 1 534 ? 119.508 137.434 139.579 1.00 0.00  ? 534 TRP B CD1 1 
ATOM 5504 C CD2 . TRP B 1 534 ? 120.001 135.472 140.552 1.00 1.48  ? 534 TRP B CD2 1 
ATOM 5505 N NE1 . TRP B 1 534 ? 120.111 137.701 140.779 1.00 0.00  ? 534 TRP B NE1 1 
ATOM 5506 C CE2 . TRP B 1 534 ? 120.425 136.520 141.397 1.00 0.71  ? 534 TRP B CE2 1 
ATOM 5507 C CE3 . TRP B 1 534 ? 120.210 134.151 140.959 1.00 0.39  ? 534 TRP B CE3 1 
ATOM 5508 C CZ2 . TRP B 1 534 ? 121.044 136.279 142.622 1.00 0.64  ? 534 TRP B CZ2 1 
ATOM 5509 C CZ3 . TRP B 1 534 ? 120.822 133.916 142.170 1.00 0.00  ? 534 TRP B CZ3 1 
ATOM 5510 C CH2 . TRP B 1 534 ? 121.234 134.967 142.988 1.00 0.00  ? 534 TRP B CH2 1 
ATOM 5511 N N   . GLY B 1 535 ? 116.300 135.250 135.968 1.00 4.51  ? 535 GLY B N   1 
ATOM 5512 C CA  . GLY B 1 535 ? 115.655 134.513 134.864 1.00 1.05  ? 535 GLY B CA  1 
ATOM 5513 C C   . GLY B 1 535 ? 115.975 133.055 134.598 1.00 0.11  ? 535 GLY B C   1 
ATOM 5514 O O   . GLY B 1 535 ? 116.112 132.689 133.414 1.00 1.44  ? 535 GLY B O   1 
ATOM 5515 N N   . LEU B 1 536 ? 116.070 132.244 135.655 1.00 5.14  ? 536 LEU B N   1 
ATOM 5516 C CA  . LEU B 1 536 ? 116.635 130.871 135.567 1.00 1.97  ? 536 LEU B CA  1 
ATOM 5517 C C   . LEU B 1 536 ? 115.495 129.843 135.507 1.00 0.78  ? 536 LEU B C   1 
ATOM 5518 O O   . LEU B 1 536 ? 114.344 130.256 135.239 1.00 6.82  ? 536 LEU B O   1 
ATOM 5519 C CB  . LEU B 1 536 ? 117.562 130.619 136.754 1.00 1.94  ? 536 LEU B CB  1 
ATOM 5520 C CG  . LEU B 1 536 ? 118.793 131.527 136.839 1.00 0.94  ? 536 LEU B CG  1 
ATOM 5521 C CD1 . LEU B 1 536 ? 119.610 131.229 138.084 1.00 0.00  ? 536 LEU B CD1 1 
ATOM 5522 C CD2 . LEU B 1 536 ? 119.649 131.396 135.590 1.00 0.63  ? 536 LEU B CD2 1 
ATOM 5523 N N   . PHE B 1 537 ? 115.806 128.564 135.740 1.00 3.46  ? 537 PHE B N   1 
ATOM 5524 C CA  . PHE B 1 537 ? 114.799 127.505 135.702 1.00 4.26  ? 537 PHE B CA  1 
ATOM 5525 C C   . PHE B 1 537 ? 113.952 127.603 134.440 1.00 3.42  ? 537 PHE B C   1 
ATOM 5526 O O   . PHE B 1 537 ? 112.781 127.216 134.429 1.00 10.51 ? 537 PHE B O   1 
ATOM 5527 C CB  . PHE B 1 537 ? 113.913 127.531 136.951 1.00 2.20  ? 537 PHE B CB  1 
ATOM 5528 C CG  . PHE B 1 537 ? 114.638 127.171 138.212 1.00 4.59  ? 537 PHE B CG  1 
ATOM 5529 C CD1 . PHE B 1 537 ? 114.877 125.847 138.537 1.00 3.43  ? 537 PHE B CD1 1 
ATOM 5530 C CD2 . PHE B 1 537 ? 115.092 128.159 139.070 1.00 2.81  ? 537 PHE B CD2 1 
ATOM 5531 C CE1 . PHE B 1 537 ? 115.548 125.514 139.697 1.00 4.11  ? 537 PHE B CE1 1 
ATOM 5532 C CE2 . PHE B 1 537 ? 115.764 127.833 140.229 1.00 2.62  ? 537 PHE B CE2 1 
ATOM 5533 C CZ  . PHE B 1 537 ? 115.992 126.508 140.544 1.00 4.12  ? 537 PHE B CZ  1 
ATOM 5534 N N   . ASP B 1 538 ? 114.546 128.134 133.377 1.00 6.57  ? 538 ASP B N   1 
ATOM 5535 C CA  . ASP B 1 538 ? 113.845 128.344 132.123 1.00 7.94  ? 538 ASP B CA  1 
ATOM 5536 C C   . ASP B 1 538 ? 113.637 127.021 131.398 1.00 5.88  ? 538 ASP B C   1 
ATOM 5537 O O   . ASP B 1 538 ? 114.472 126.115 131.455 1.00 8.62  ? 538 ASP B O   1 
ATOM 5538 C CB  . ASP B 1 538 ? 114.626 129.315 131.237 1.00 3.77  ? 538 ASP B CB  1 
ATOM 5539 C CG  . ASP B 1 538 ? 113.736 130.069 130.275 1.00 9.42  ? 538 ASP B CG  1 
ATOM 5540 O OD1 . ASP B 1 538 ? 112.501 130.023 130.446 1.00 10.25 ? 538 ASP B OD1 1 
ATOM 5541 O OD2 . ASP B 1 538 ? 114.271 130.713 129.349 1.00 10.29 ? 538 ASP B OD2 1 
ATOM 5542 N N   . LYS B 1 539 ? 112.498 126.916 130.714 1.00 7.21  ? 539 LYS B N   1 
ATOM 5543 C CA  . LYS B 1 539 ? 112.192 125.728 129.930 1.00 5.82  ? 539 LYS B CA  1 
ATOM 5544 C C   . LYS B 1 539 ? 113.098 125.577 128.715 1.00 9.45  ? 539 LYS B C   1 
ATOM 5545 O O   . LYS B 1 539 ? 113.143 124.493 128.125 1.00 12.19 ? 539 LYS B O   1 
ATOM 5546 C CB  . LYS B 1 539 ? 110.729 125.761 129.487 1.00 6.73  ? 539 LYS B CB  1 
ATOM 5547 C CG  . LYS B 1 539 ? 110.378 126.954 128.619 1.00 5.19  ? 539 LYS B CG  1 
ATOM 5548 C CD  . LYS B 1 539 ? 108.876 127.088 128.445 1.00 7.42  ? 539 LYS B CD  1 
ATOM 5549 C CE  . LYS B 1 539 ? 108.515 127.376 126.998 1.00 6.39  ? 539 LYS B CE  1 
ATOM 5550 N NZ  . LYS B 1 539 ? 108.898 126.253 126.102 1.00 10.23 ? 539 LYS B NZ  1 
ATOM 5551 N N   . ASN B 1 540 ? 113.819 126.631 128.335 1.00 7.66  ? 540 ASN B N   1 
ATOM 5552 C CA  . ASN B 1 540 ? 114.720 126.592 127.192 1.00 4.87  ? 540 ASN B CA  1 
ATOM 5553 C C   . ASN B 1 540 ? 116.130 126.147 127.555 1.00 8.46  ? 540 ASN B C   1 
ATOM 5554 O O   . ASN B 1 540 ? 117.009 126.164 126.688 1.00 8.53  ? 540 ASN B O   1 
ATOM 5555 C CB  . ASN B 1 540 ? 114.780 127.968 126.519 1.00 6.30  ? 540 ASN B CB  1 
ATOM 5556 C CG  . ASN B 1 540 ? 113.437 128.406 125.968 1.00 10.59 ? 540 ASN B CG  1 
ATOM 5557 O OD1 . ASN B 1 540 ? 112.412 127.777 126.230 1.00 12.58 ? 540 ASN B OD1 1 
ATOM 5558 N ND2 . ASN B 1 540 ? 113.436 129.487 125.197 1.00 11.67 ? 540 ASN B ND2 1 
ATOM 5559 N N   . ALA B 1 541 ? 116.371 125.770 128.809 1.00 6.12  ? 541 ALA B N   1 
ATOM 5560 C CA  . ALA B 1 541 ? 117.680 125.276 129.217 1.00 5.35  ? 541 ALA B CA  1 
ATOM 5561 C C   . ALA B 1 541 ? 117.945 123.901 128.619 1.00 10.56 ? 541 ALA B C   1 
ATOM 5562 O O   . ALA B 1 541 ? 117.328 122.911 129.026 1.00 10.36 ? 541 ALA B O   1 
ATOM 5563 C CB  . ALA B 1 541 ? 117.782 125.223 130.741 1.00 5.85  ? 541 ALA B CB  1 
ATOM 5564 N N   . GLY B 1 542 ? 118.857 123.828 127.654 1.00 10.28 ? 542 GLY B N   1 
ATOM 5565 C CA  . GLY B 1 542 ? 119.149 122.571 126.997 1.00 10.41 ? 542 GLY B CA  1 
ATOM 5566 C C   . GLY B 1 542 ? 119.872 121.581 127.885 1.00 8.84  ? 542 GLY B C   1 
ATOM 5567 O O   . GLY B 1 542 ? 119.311 120.546 128.259 1.00 10.51 ? 542 GLY B O   1 
ATOM 5568 N N   . GLU B 1 543 ? 121.119 121.888 128.232 1.00 11.16 ? 543 GLU B N   1 
ATOM 5569 C CA  . GLU B 1 543 ? 121.929 121.027 129.081 1.00 6.80  ? 543 GLU B CA  1 
ATOM 5570 C C   . GLU B 1 543 ? 122.399 121.722 130.350 1.00 7.34  ? 543 GLU B C   1 
ATOM 5571 O O   . GLU B 1 543 ? 122.926 121.057 131.246 1.00 9.49  ? 543 GLU B O   1 
ATOM 5572 C CB  . GLU B 1 543 ? 123.135 120.497 128.298 1.00 8.67  ? 543 GLU B CB  1 
ATOM 5573 C CG  . GLU B 1 543 ? 123.001 119.047 127.854 1.00 9.16  ? 543 GLU B CG  1 
ATOM 5574 C CD  . GLU B 1 543 ? 121.828 118.823 126.918 1.00 12.88 ? 543 GLU B CD  1 
ATOM 5575 O OE1 . GLU B 1 543 ? 120.794 118.292 127.376 1.00 11.85 ? 543 GLU B OE1 1 
ATOM 5576 O OE2 . GLU B 1 543 ? 121.939 119.175 125.724 1.00 11.37 ? 543 GLU B OE2 1 
ATOM 5577 N N   . ASN B 1 544 ? 122.222 123.041 130.450 1.00 9.29  ? 544 ASN B N   1 
ATOM 5578 C CA  . ASN B 1 544 ? 122.462 123.766 131.697 1.00 5.45  ? 544 ASN B CA  1 
ATOM 5579 C C   . ASN B 1 544 ? 121.218 123.606 132.564 1.00 7.46  ? 544 ASN B C   1 
ATOM 5580 O O   . ASN B 1 544 ? 120.302 124.431 132.557 1.00 7.14  ? 544 ASN B O   1 
ATOM 5581 C CB  . ASN B 1 544 ? 122.779 125.232 131.424 1.00 5.40  ? 544 ASN B CB  1 
ATOM 5582 C CG  . ASN B 1 544 ? 123.797 125.416 130.317 1.00 8.81  ? 544 ASN B CG  1 
ATOM 5583 O OD1 . ASN B 1 544 ? 124.865 124.804 130.330 1.00 6.16  ? 544 ASN B OD1 1 
ATOM 5584 N ND2 . ASN B 1 544 ? 123.474 126.271 129.354 1.00 6.59  ? 544 ASN B ND2 1 
ATOM 5585 N N   . THR B 1 545 ? 121.190 122.507 133.315 1.00 6.54  ? 545 THR B N   1 
ATOM 5586 C CA  . THR B 1 545 ? 120.017 122.145 134.104 1.00 4.15  ? 545 THR B CA  1 
ATOM 5587 C C   . THR B 1 545 ? 119.669 123.235 135.107 1.00 4.47  ? 545 THR B C   1 
ATOM 5588 O O   . THR B 1 545 ? 120.532 123.705 135.854 1.00 6.46  ? 545 THR B O   1 
ATOM 5589 C CB  . THR B 1 545 ? 120.268 120.821 134.830 1.00 4.02  ? 545 THR B CB  1 
ATOM 5590 O OG1 . THR B 1 545 ? 121.412 120.948 135.683 1.00 6.88  ? 545 THR B OG1 1 
ATOM 5591 C CG2 . THR B 1 545 ? 120.509 119.702 133.831 1.00 3.73  ? 545 THR B CG2 1 
ATOM 5592 N N   . PHE B 1 546 ? 118.397 123.642 135.102 1.00 3.73  ? 546 PHE B N   1 
ATOM 5593 C CA  . PHE B 1 546 ? 117.809 124.630 136.004 1.00 3.30  ? 546 PHE B CA  1 
ATOM 5594 C C   . PHE B 1 546 ? 118.368 126.033 135.804 1.00 6.76  ? 546 PHE B C   1 
ATOM 5595 O O   . PHE B 1 546 ? 117.947 126.965 136.501 1.00 8.33  ? 546 PHE B O   1 
ATOM 5596 C CB  . PHE B 1 546 ? 117.963 124.217 137.472 1.00 5.82  ? 546 PHE B CB  1 
ATOM 5597 C CG  . PHE B 1 546 ? 117.512 122.813 137.751 1.00 7.55  ? 546 PHE B CG  1 
ATOM 5598 C CD1 . PHE B 1 546 ? 116.280 122.368 137.303 1.00 4.75  ? 546 PHE B CD1 1 
ATOM 5599 C CD2 . PHE B 1 546 ? 118.320 121.938 138.455 1.00 9.47  ? 546 PHE B CD2 1 
ATOM 5600 C CE1 . PHE B 1 546 ? 115.861 121.078 137.553 1.00 10.15 ? 546 PHE B CE1 1 
ATOM 5601 C CE2 . PHE B 1 546 ? 117.905 120.645 138.710 1.00 5.68  ? 546 PHE B CE2 1 
ATOM 5602 C CZ  . PHE B 1 546 ? 116.674 120.215 138.258 1.00 7.18  ? 546 PHE B CZ  1 
ATOM 5603 N N   . LEU B 1 547 ? 119.312 126.208 134.893 1.00 5.94  ? 547 LEU B N   1 
ATOM 5604 C CA  . LEU B 1 547 ? 119.813 127.521 134.495 1.00 2.59  ? 547 LEU B CA  1 
ATOM 5605 C C   . LEU B 1 547 ? 119.038 127.975 133.256 1.00 7.69  ? 547 LEU B C   1 
ATOM 5606 O O   . LEU B 1 547 ? 117.970 127.416 132.995 1.00 11.22 ? 547 LEU B O   1 
ATOM 5607 C CB  . LEU B 1 547 ? 121.326 127.464 134.324 1.00 3.80  ? 547 LEU B CB  1 
ATOM 5608 C CG  . LEU B 1 547 ? 122.090 126.678 135.391 1.00 2.08  ? 547 LEU B CG  1 
ATOM 5609 C CD1 . LEU B 1 547 ? 123.575 126.646 135.072 1.00 2.13  ? 547 LEU B CD1 1 
ATOM 5610 C CD2 . LEU B 1 547 ? 121.844 127.270 136.769 1.00 0.45  ? 547 LEU B CD2 1 
ATOM 5611 N N   . ARG B 1 548 ? 119.497 128.984 132.522 1.00 5.94  ? 548 ARG B N   1 
ATOM 5612 C CA  . ARG B 1 548 ? 118.897 129.373 131.256 1.00 2.15  ? 548 ARG B CA  1 
ATOM 5613 C C   . ARG B 1 548 ? 119.818 128.966 130.113 1.00 3.85  ? 548 ARG B C   1 
ATOM 5614 O O   . ARG B 1 548 ? 120.939 128.501 130.330 1.00 8.67  ? 548 ARG B O   1 
ATOM 5615 C CB  . ARG B 1 548 ? 118.595 130.875 131.243 1.00 7.44  ? 548 ARG B CB  1 
ATOM 5616 C CG  . ARG B 1 548 ? 119.805 131.730 131.542 1.00 2.32  ? 548 ARG B CG  1 
ATOM 5617 C CD  . ARG B 1 548 ? 119.432 133.202 131.672 1.00 2.86  ? 548 ARG B CD  1 
ATOM 5618 N NE  . ARG B 1 548 ? 120.174 133.911 132.714 1.00 3.82  ? 548 ARG B NE  1 
ATOM 5619 C CZ  . ARG B 1 548 ? 121.488 133.883 132.907 1.00 5.60  ? 548 ARG B CZ  1 
ATOM 5620 N NH1 . ARG B 1 548 ? 122.306 133.257 132.076 1.00 0.00  ? 548 ARG B NH1 1 
ATOM 5621 N NH2 . ARG B 1 548 ? 121.998 134.513 133.961 1.00 4.26  ? 548 ARG B NH2 1 
ATOM 5622 N N   . GLU B 1 549 ? 119.320 129.141 128.887 1.00 6.41  ? 549 GLU B N   1 
ATOM 5623 C CA  . GLU B 1 549 ? 120.025 128.634 127.711 1.00 8.58  ? 549 GLU B CA  1 
ATOM 5624 C C   . GLU B 1 549 ? 121.384 129.304 127.537 1.00 4.62  ? 549 GLU B C   1 
ATOM 5625 O O   . GLU B 1 549 ? 122.367 128.649 127.173 1.00 11.07 ? 549 GLU B O   1 
ATOM 5626 C CB  . GLU B 1 549 ? 119.162 128.819 126.461 1.00 10.23 ? 549 GLU B CB  1 
ATOM 5627 C CG  . GLU B 1 549 ? 118.675 130.240 126.232 1.00 6.84  ? 549 GLU B CG  1 
ATOM 5628 C CD  . GLU B 1 549 ? 118.424 130.537 124.768 1.00 9.38  ? 549 GLU B CD  1 
ATOM 5629 O OE1 . GLU B 1 549 ? 117.675 129.770 124.126 1.00 14.27 ? 549 GLU B OE1 1 
ATOM 5630 O OE2 . GLU B 1 549 ? 118.979 131.532 124.258 1.00 13.63 ? 549 GLU B OE2 1 
ATOM 5631 N N   . GLU B 1 550 ? 121.461 130.606 127.786 1.00 9.79  ? 550 GLU B N   1 
ATOM 5632 C CA  . GLU B 1 550 ? 122.718 131.321 127.627 1.00 7.78  ? 550 GLU B CA  1 
ATOM 5633 C C   . GLU B 1 550 ? 123.263 131.678 129.004 1.00 4.97  ? 550 GLU B C   1 
ATOM 5634 O O   . GLU B 1 550 ? 122.587 132.329 129.806 1.00 8.53  ? 550 GLU B O   1 
ATOM 5635 C CB  . GLU B 1 550 ? 122.495 132.569 126.758 1.00 9.40  ? 550 GLU B CB  1 
ATOM 5636 C CG  . GLU B 1 550 ? 123.722 133.317 126.169 1.00 7.57  ? 550 GLU B CG  1 
ATOM 5637 C CD  . GLU B 1 550 ? 124.787 133.807 127.146 1.00 11.42 ? 550 GLU B CD  1 
ATOM 5638 O OE1 . GLU B 1 550 ? 124.525 133.949 128.353 1.00 10.36 ? 550 GLU B OE1 1 
ATOM 5639 O OE2 . GLU B 1 550 ? 125.918 134.059 126.683 1.00 14.84 ? 550 GLU B OE2 1 
ATOM 5640 N N   . ILE B 1 551 ? 124.494 131.245 129.279 1.00 6.76  ? 551 ILE B N   1 
ATOM 5641 C CA  . ILE B 1 551 ? 125.209 131.672 130.478 1.00 2.03  ? 551 ILE B CA  1 
ATOM 5642 C C   . ILE B 1 551 ? 126.553 132.260 130.060 1.00 4.93  ? 551 ILE B C   1 
ATOM 5643 O O   . ILE B 1 551 ? 127.300 131.660 129.279 1.00 12.43 ? 551 ILE B O   1 
ATOM 5644 C CB  . ILE B 1 551 ? 125.370 130.526 131.500 1.00 8.06  ? 551 ILE B CB  1 
ATOM 5645 C CG1 . ILE B 1 551 ? 126.347 129.450 131.015 1.00 3.51  ? 551 ILE B CG1 1 
ATOM 5646 C CG2 . ILE B 1 551 ? 124.019 129.909 131.835 1.00 5.42  ? 551 ILE B CG2 1 
ATOM 5647 C CD1 . ILE B 1 551 ? 126.582 128.347 132.024 1.00 4.42  ? 551 ILE B CD1 1 
ATOM 5648 N N   . VAL B 1 552 ? 126.851 133.465 130.549 1.00 5.13  ? 552 VAL B N   1 
ATOM 5649 C CA  . VAL B 1 552 ? 128.094 134.132 130.180 1.00 1.95  ? 552 VAL B CA  1 
ATOM 5650 C C   . VAL B 1 552 ? 129.241 133.770 131.113 1.00 5.75  ? 552 VAL B C   1 
ATOM 5651 O O   . VAL B 1 552 ? 130.361 133.534 130.644 1.00 14.32 ? 552 VAL B O   1 
ATOM 5652 C CB  . VAL B 1 552 ? 127.902 135.657 130.156 1.00 4.63  ? 552 VAL B CB  1 
ATOM 5653 C CG1 . VAL B 1 552 ? 129.199 136.351 129.793 1.00 5.19  ? 552 VAL B CG1 1 
ATOM 5654 C CG2 . VAL B 1 552 ? 126.797 136.038 129.188 1.00 5.16  ? 552 VAL B CG2 1 
ATOM 5655 N N   . TYR B 1 553 ? 128.995 133.715 132.409 1.00 6.72  ? 553 TYR B N   1 
ATOM 5656 C CA  . TYR B 1 553 ? 130.044 133.392 133.363 1.00 3.36  ? 553 TYR B CA  1 
ATOM 5657 C C   . TYR B 1 553 ? 130.501 131.946 133.168 1.00 4.59  ? 553 TYR B C   1 
ATOM 5658 O O   . TYR B 1 553 ? 129.676 131.062 132.921 1.00 5.26  ? 553 TYR B O   1 
ATOM 5659 C CB  . TYR B 1 553 ? 129.545 133.614 134.785 1.00 1.35  ? 553 TYR B CB  1 
ATOM 5660 C CG  . TYR B 1 553 ? 129.073 135.033 135.006 1.00 0.69  ? 553 TYR B CG  1 
ATOM 5661 C CD1 . TYR B 1 553 ? 129.951 136.102 134.894 1.00 0.00  ? 553 TYR B CD1 1 
ATOM 5662 C CD2 . TYR B 1 553 ? 127.744 135.306 135.302 1.00 4.05  ? 553 TYR B CD2 1 
ATOM 5663 C CE1 . TYR B 1 553 ? 129.522 137.401 135.083 1.00 0.00  ? 553 TYR B CE1 1 
ATOM 5664 C CE2 . TYR B 1 553 ? 127.307 136.601 135.494 1.00 0.42  ? 553 TYR B CE2 1 
ATOM 5665 C CZ  . TYR B 1 553 ? 128.199 137.645 135.382 1.00 0.00  ? 553 TYR B CZ  1 
ATOM 5666 O OH  . TYR B 1 553 ? 127.765 138.935 135.572 1.00 0.00  ? 553 TYR B OH  1 
ATOM 5667 N N   . PRO B 1 554 ? 131.806 131.681 133.274 1.00 6.24  ? 554 PRO B N   1 
ATOM 5668 C CA  . PRO B 1 554 ? 132.335 130.405 132.766 1.00 4.35  ? 554 PRO B CA  1 
ATOM 5669 C C   . PRO B 1 554 ? 131.932 129.184 133.576 1.00 8.35  ? 554 PRO B C   1 
ATOM 5670 O O   . PRO B 1 554 ? 131.646 128.137 132.982 1.00 14.60 ? 554 PRO B O   1 
ATOM 5671 C CB  . PRO B 1 554 ? 133.852 130.632 132.803 1.00 3.90  ? 554 PRO B CB  1 
ATOM 5672 C CG  . PRO B 1 554 ? 134.033 131.579 133.944 1.00 4.37  ? 554 PRO B CG  1 
ATOM 5673 C CD  . PRO B 1 554 ? 132.879 132.539 133.807 1.00 5.90  ? 554 PRO B CD  1 
ATOM 5674 N N   . GLN B 1 555 ? 131.897 129.273 134.902 1.00 4.57  ? 555 GLN B N   1 
ATOM 5675 C CA  . GLN B 1 555 ? 131.656 128.117 135.756 1.00 3.05  ? 555 GLN B CA  1 
ATOM 5676 C C   . GLN B 1 555 ? 130.162 127.962 136.009 1.00 4.75  ? 555 GLN B C   1 
ATOM 5677 O O   . GLN B 1 555 ? 129.501 128.911 136.444 1.00 12.85 ? 555 GLN B O   1 
ATOM 5678 C CB  . GLN B 1 555 ? 132.410 128.251 137.079 1.00 7.37  ? 555 GLN B CB  1 
ATOM 5679 C CG  . GLN B 1 555 ? 133.827 127.690 137.059 1.00 6.99  ? 555 GLN B CG  1 
ATOM 5680 C CD  . GLN B 1 555 ? 133.899 126.266 136.533 1.00 7.02  ? 555 GLN B CD  1 
ATOM 5681 O OE1 . GLN B 1 555 ? 132.996 125.459 136.757 1.00 6.11  ? 555 GLN B OE1 1 
ATOM 5682 N NE2 . GLN B 1 555 ? 134.980 125.952 135.831 1.00 11.15 ? 555 GLN B NE2 1 
ATOM 5683 N N   . LYS B 1 556 ? 129.635 126.767 135.736 1.00 4.96  ? 556 LYS B N   1 
ATOM 5684 C CA  . LYS B 1 556 ? 128.247 126.462 136.062 1.00 2.86  ? 556 LYS B CA  1 
ATOM 5685 C C   . LYS B 1 556 ? 128.008 126.358 137.560 1.00 2.02  ? 556 LYS B C   1 
ATOM 5686 O O   . LYS B 1 556 ? 126.879 126.587 138.007 1.00 2.10  ? 556 LYS B O   1 
ATOM 5687 C CB  . LYS B 1 556 ? 127.818 125.157 135.389 1.00 1.29  ? 556 LYS B CB  1 
ATOM 5688 C CG  . LYS B 1 556 ? 126.957 125.346 134.157 1.00 3.47  ? 556 LYS B CG  1 
ATOM 5689 C CD  . LYS B 1 556 ? 126.036 124.158 133.948 1.00 4.30  ? 556 LYS B CD  1 
ATOM 5690 C CE  . LYS B 1 556 ? 126.705 123.074 133.122 1.00 4.95  ? 556 LYS B CE  1 
ATOM 5691 N NZ  . LYS B 1 556 ? 125.793 121.921 132.893 1.00 4.10  ? 556 LYS B NZ  1 
ATOM 5692 N N   . ALA B 1 557 ? 129.030 126.013 138.341 1.00 4.10  ? 557 ALA B N   1 
ATOM 5693 C CA  . ALA B 1 557 ? 128.906 125.920 139.788 1.00 3.19  ? 557 ALA B CA  1 
ATOM 5694 C C   . ALA B 1 557 ? 128.622 127.263 140.443 1.00 5.74  ? 557 ALA B C   1 
ATOM 5695 O O   . ALA B 1 557 ? 128.044 127.292 141.538 1.00 2.96  ? 557 ALA B O   1 
ATOM 5696 C CB  . ALA B 1 557 ? 130.179 125.316 140.390 1.00 2.82  ? 557 ALA B CB  1 
ATOM 5697 N N   . TYR B 1 558 ? 129.007 128.369 139.798 1.00 3.12  ? 558 TYR B N   1 
ATOM 5698 C CA  . TYR B 1 558 ? 128.701 129.688 140.340 1.00 4.32  ? 558 TYR B CA  1 
ATOM 5699 C C   . TYR B 1 558 ? 127.199 129.891 140.464 1.00 2.38  ? 558 TYR B C   1 
ATOM 5700 O O   . TYR B 1 558 ? 126.721 130.421 141.470 1.00 0.00  ? 558 TYR B O   1 
ATOM 5701 C CB  . TYR B 1 558 ? 129.303 130.782 139.458 1.00 3.97  ? 558 TYR B CB  1 
ATOM 5702 C CG  . TYR B 1 558 ? 130.812 130.850 139.464 1.00 4.94  ? 558 TYR B CG  1 
ATOM 5703 C CD1 . TYR B 1 558 ? 131.550 130.335 140.522 1.00 5.18  ? 558 TYR B CD1 1 
ATOM 5704 C CD2 . TYR B 1 558 ? 131.497 131.456 138.422 1.00 4.91  ? 558 TYR B CD2 1 
ATOM 5705 C CE1 . TYR B 1 558 ? 132.930 130.404 140.529 1.00 3.56  ? 558 TYR B CE1 1 
ATOM 5706 C CE2 . TYR B 1 558 ? 132.874 131.531 138.421 1.00 5.43  ? 558 TYR B CE2 1 
ATOM 5707 C CZ  . TYR B 1 558 ? 133.585 131.004 139.477 1.00 4.14  ? 558 TYR B CZ  1 
ATOM 5708 O OH  . TYR B 1 558 ? 134.958 131.080 139.476 1.00 9.99  ? 558 TYR B OH  1 
ATOM 5709 N N   . TYR B 1 559 ? 126.440 129.470 139.451 1.00 2.95  ? 559 TYR B N   1 
ATOM 5710 C CA  . TYR B 1 559 ? 124.996 129.672 139.466 1.00 0.67  ? 559 TYR B CA  1 
ATOM 5711 C C   . TYR B 1 559 ? 124.324 128.842 140.556 1.00 2.03  ? 559 TYR B C   1 
ATOM 5712 O O   . TYR B 1 559 ? 123.435 129.338 141.255 1.00 4.00  ? 559 TYR B O   1 
ATOM 5713 C CB  . TYR B 1 559 ? 124.412 129.348 138.091 1.00 3.40  ? 559 TYR B CB  1 
ATOM 5714 C CG  . TYR B 1 559 ? 124.889 130.267 136.984 1.00 0.53  ? 559 TYR B CG  1 
ATOM 5715 C CD1 . TYR B 1 559 ? 126.179 130.165 136.474 1.00 3.61  ? 559 TYR B CD1 1 
ATOM 5716 C CD2 . TYR B 1 559 ? 124.050 131.236 136.448 1.00 0.00  ? 559 TYR B CD2 1 
ATOM 5717 C CE1 . TYR B 1 559 ? 126.618 131.000 135.468 1.00 5.65  ? 559 TYR B CE1 1 
ATOM 5718 C CE2 . TYR B 1 559 ? 124.482 132.076 135.440 1.00 0.35  ? 559 TYR B CE2 1 
ATOM 5719 C CZ  . TYR B 1 559 ? 125.766 131.954 134.954 1.00 3.08  ? 559 TYR B CZ  1 
ATOM 5720 O OH  . TYR B 1 559 ? 126.206 132.786 133.952 1.00 5.07  ? 559 TYR B OH  1 
ATOM 5721 N N   . TYR B 1 560 ? 124.734 127.581 140.721 1.00 0.14  ? 560 TYR B N   1 
ATOM 5722 C CA  . TYR B 1 560 ? 124.158 126.749 141.777 1.00 3.41  ? 560 TYR B CA  1 
ATOM 5723 C C   . TYR B 1 560 ? 124.508 127.286 143.161 1.00 0.00  ? 560 TYR B C   1 
ATOM 5724 O O   . TYR B 1 560 ? 123.646 127.346 144.052 1.00 2.93  ? 560 TYR B O   1 
ATOM 5725 C CB  . TYR B 1 560 ? 124.635 125.304 141.630 1.00 2.09  ? 560 TYR B CB  1 
ATOM 5726 C CG  . TYR B 1 560 ? 124.240 124.652 140.327 1.00 1.54  ? 560 TYR B CG  1 
ATOM 5727 C CD1 . TYR B 1 560 ? 122.930 124.702 139.873 1.00 3.50  ? 560 TYR B CD1 1 
ATOM 5728 C CD2 . TYR B 1 560 ? 125.176 123.981 139.553 1.00 1.96  ? 560 TYR B CD2 1 
ATOM 5729 C CE1 . TYR B 1 560 ? 122.564 124.106 138.685 1.00 2.12  ? 560 TYR B CE1 1 
ATOM 5730 C CE2 . TYR B 1 560 ? 124.819 123.383 138.361 1.00 4.00  ? 560 TYR B CE2 1 
ATOM 5731 C CZ  . TYR B 1 560 ? 123.512 123.449 137.932 1.00 3.80  ? 560 TYR B CZ  1 
ATOM 5732 O OH  . TYR B 1 560 ? 123.150 122.855 136.746 1.00 5.64  ? 560 TYR B OH  1 
ATOM 5733 N N   . CYS B 1 561 ? 125.769 127.680 143.358 1.00 0.00  ? 561 CYS B N   1 
ATOM 5734 C CA  . CYS B 1 561 ? 126.169 128.267 144.631 1.00 2.02  ? 561 CYS B CA  1 
ATOM 5735 C C   . CYS B 1 561 ? 125.393 129.548 144.910 1.00 2.10  ? 561 CYS B C   1 
ATOM 5736 O O   . CYS B 1 561 ? 124.986 129.801 146.050 1.00 4.21  ? 561 CYS B O   1 
ATOM 5737 C CB  . CYS B 1 561 ? 127.674 128.537 144.632 1.00 4.33  ? 561 CYS B CB  1 
ATOM 5738 S SG  . CYS B 1 561 ? 128.704 127.066 144.838 1.00 15.29 ? 561 CYS B SG  1 
ATOM 5739 N N   . ALA B 1 562 ? 125.174 130.366 143.875 1.00 1.28  ? 562 ALA B N   1 
ATOM 5740 C CA  . ALA B 1 562 ? 124.402 131.592 144.029 1.00 2.76  ? 562 ALA B CA  1 
ATOM 5741 C C   . ALA B 1 562 ? 122.955 131.294 144.392 1.00 0.74  ? 562 ALA B C   1 
ATOM 5742 O O   . ALA B 1 562 ? 122.364 131.989 145.223 1.00 3.52  ? 562 ALA B O   1 
ATOM 5743 C CB  . ALA B 1 562 ? 124.475 132.420 142.749 1.00 0.00  ? 562 ALA B CB  1 
ATOM 5744 N N   . ILE B 1 563 ? 122.366 130.268 143.775 1.00 0.49  ? 563 ILE B N   1 
ATOM 5745 C CA  . ILE B 1 563 ? 120.997 129.884 144.115 1.00 0.86  ? 563 ILE B CA  1 
ATOM 5746 C C   . ILE B 1 563 ? 120.908 129.510 145.589 1.00 0.48  ? 563 ILE B C   1 
ATOM 5747 O O   . ILE B 1 563 ? 120.015 129.969 146.313 1.00 6.23  ? 563 ILE B O   1 
ATOM 5748 C CB  . ILE B 1 563 ? 120.520 128.733 143.211 1.00 1.42  ? 563 ILE B CB  1 
ATOM 5749 C CG1 . ILE B 1 563 ? 120.293 129.226 141.783 1.00 2.63  ? 563 ILE B CG1 1 
ATOM 5750 C CG2 . ILE B 1 563 ? 119.247 128.106 143.763 1.00 3.94  ? 563 ILE B CG2 1 
ATOM 5751 C CD1 . ILE B 1 563 ? 120.043 128.113 140.792 1.00 1.66  ? 563 ILE B CD1 1 
ATOM 5752 N N   . ILE B 1 564 ? 121.851 128.690 146.059 1.00 2.86  ? 564 ILE B N   1 
ATOM 5753 C CA  . ILE B 1 564 ? 121.824 128.249 147.454 1.00 4.42  ? 564 ILE B CA  1 
ATOM 5754 C C   . ILE B 1 564 ? 121.996 129.439 148.397 1.00 2.38  ? 564 ILE B C   1 
ATOM 5755 O O   . ILE B 1 564 ? 121.238 129.609 149.368 1.00 3.80  ? 564 ILE B O   1 
ATOM 5756 C CB  . ILE B 1 564 ? 122.899 127.175 147.697 1.00 3.86  ? 564 ILE B CB  1 
ATOM 5757 C CG1 . ILE B 1 564 ? 122.677 125.975 146.775 1.00 3.48  ? 564 ILE B CG1 1 
ATOM 5758 C CG2 . ILE B 1 564 ? 122.896 126.733 149.153 1.00 3.82  ? 564 ILE B CG2 1 
ATOM 5759 C CD1 . ILE B 1 564 ? 121.332 125.312 146.947 1.00 6.17  ? 564 ILE B CD1 1 
ATOM 5760 N N   . GLU B 1 565 ? 122.997 130.282 148.122 1.00 0.27  ? 565 GLU B N   1 
ATOM 5761 C CA  . GLU B 1 565 ? 123.261 131.412 149.005 1.00 2.87  ? 565 GLU B CA  1 
ATOM 5762 C C   . GLU B 1 565 ? 122.086 132.380 149.023 1.00 5.04  ? 565 GLU B C   1 
ATOM 5763 O O   . GLU B 1 565 ? 121.741 132.916 150.078 1.00 7.56  ? 565 GLU B O   1 
ATOM 5764 C CB  . GLU B 1 565 ? 124.564 132.121 148.612 1.00 2.83  ? 565 GLU B CB  1 
ATOM 5765 C CG  . GLU B 1 565 ? 124.550 132.891 147.296 1.00 2.34  ? 565 GLU B CG  1 
ATOM 5766 C CD  . GLU B 1 565 ? 124.019 134.309 147.433 1.00 3.84  ? 565 GLU B CD  1 
ATOM 5767 O OE1 . GLU B 1 565 ? 124.255 134.941 148.482 1.00 0.00  ? 565 GLU B OE1 1 
ATOM 5768 O OE2 . GLU B 1 565 ? 123.351 134.784 146.491 1.00 7.47  ? 565 GLU B OE2 1 
ATOM 5769 N N   . ASP B 1 566 ? 121.450 132.609 147.871 1.00 0.00  ? 566 ASP B N   1 
ATOM 5770 C CA  . ASP B 1 566 ? 120.303 133.508 147.830 1.00 2.16  ? 566 ASP B CA  1 
ATOM 5771 C C   . ASP B 1 566 ? 119.122 132.931 148.596 1.00 0.01  ? 566 ASP B C   1 
ATOM 5772 O O   . ASP B 1 566 ? 118.418 133.665 149.300 1.00 2.59  ? 566 ASP B O   1 
ATOM 5773 C CB  . ASP B 1 566 ? 119.913 133.802 146.383 1.00 0.13  ? 566 ASP B CB  1 
ATOM 5774 C CG  . ASP B 1 566 ? 119.162 135.109 146.239 1.00 0.00  ? 566 ASP B CG  1 
ATOM 5775 O OD1 . ASP B 1 566 ? 119.812 136.172 146.263 1.00 4.06  ? 566 ASP B OD1 1 
ATOM 5776 O OD2 . ASP B 1 566 ? 117.923 135.074 146.104 1.00 0.00  ? 566 ASP B OD2 1 
ATOM 5777 N N   . VAL B 1 567 ? 118.901 131.618 148.486 1.00 3.11  ? 567 VAL B N   1 
ATOM 5778 C CA  . VAL B 1 567 ? 117.814 130.984 149.228 1.00 2.15  ? 567 VAL B CA  1 
ATOM 5779 C C   . VAL B 1 567 ? 118.006 131.191 150.726 1.00 2.22  ? 567 VAL B C   1 
ATOM 5780 O O   . VAL B 1 567 ? 117.065 131.543 151.447 1.00 3.99  ? 567 VAL B O   1 
ATOM 5781 C CB  . VAL B 1 567 ? 117.716 129.489 148.872 1.00 3.29  ? 567 VAL B CB  1 
ATOM 5782 C CG1 . VAL B 1 567 ? 116.870 128.752 149.896 1.00 1.55  ? 567 VAL B CG1 1 
ATOM 5783 C CG2 . VAL B 1 567 ? 117.133 129.308 147.479 1.00 1.57  ? 567 VAL B CG2 1 
ATOM 5784 N N   . ILE B 1 568 ? 119.230 130.987 151.216 1.00 2.54  ? 568 ILE B N   1 
ATOM 5785 C CA  . ILE B 1 568 ? 119.483 131.163 152.649 1.00 1.64  ? 568 ILE B CA  1 
ATOM 5786 C C   . ILE B 1 568 ? 119.386 132.640 153.044 1.00 1.69  ? 568 ILE B C   1 
ATOM 5787 O O   . ILE B 1 568 ? 118.743 133.007 154.044 1.00 2.60  ? 568 ILE B O   1 
ATOM 5788 C CB  . ILE B 1 568 ? 120.849 130.559 153.023 1.00 1.48  ? 568 ILE B CB  1 
ATOM 5789 C CG1 . ILE B 1 568 ? 120.799 129.032 152.916 1.00 4.31  ? 568 ILE B CG1 1 
ATOM 5790 C CG2 . ILE B 1 568 ? 121.269 130.990 154.416 1.00 3.24  ? 568 ILE B CG2 1 
ATOM 5791 C CD1 . ILE B 1 568 ? 122.151 128.374 152.751 1.00 2.82  ? 568 ILE B CD1 1 
ATOM 5792 N N   . LEU B 1 569 ? 120.007 133.514 152.256 1.00 0.00  ? 569 LEU B N   1 
ATOM 5793 C CA  . LEU B 1 569 ? 120.161 134.900 152.661 1.00 0.00  ? 569 LEU B CA  1 
ATOM 5794 C C   . LEU B 1 569 ? 118.885 135.717 152.511 1.00 0.49  ? 569 LEU B C   1 
ATOM 5795 O O   . LEU B 1 569 ? 118.754 136.735 153.189 1.00 1.37  ? 569 LEU B O   1 
ATOM 5796 C CB  . LEU B 1 569 ? 121.309 135.545 151.879 1.00 0.44  ? 569 LEU B CB  1 
ATOM 5797 C CG  . LEU B 1 569 ? 122.698 135.015 152.256 1.00 0.00  ? 569 LEU B CG  1 
ATOM 5798 C CD1 . LEU B 1 569 ? 123.809 135.896 151.702 1.00 0.19  ? 569 LEU B CD1 1 
ATOM 5799 C CD2 . LEU B 1 569 ? 122.833 134.860 153.768 1.00 0.00  ? 569 LEU B CD2 1 
ATOM 5800 N N   . ARG B 1 570 ? 117.927 135.295 151.680 1.00 0.00  ? 570 ARG B N   1 
ATOM 5801 C CA  . ARG B 1 570 ? 116.650 136.006 151.651 1.00 0.94  ? 570 ARG B CA  1 
ATOM 5802 C C   . ARG B 1 570 ? 115.895 135.839 152.967 1.00 0.79  ? 570 ARG B C   1 
ATOM 5803 O O   . ARG B 1 570 ? 115.342 136.810 153.504 1.00 2.51  ? 570 ARG B O   1 
ATOM 5804 C CB  . ARG B 1 570 ? 115.801 135.527 150.473 1.00 0.00  ? 570 ARG B CB  1 
ATOM 5805 C CG  . ARG B 1 570 ? 116.029 136.309 149.184 1.00 0.54  ? 570 ARG B CG  1 
ATOM 5806 C CD  . ARG B 1 570 ? 115.768 137.796 149.377 1.00 0.00  ? 570 ARG B CD  1 
ATOM 5807 N NE  . ARG B 1 570 ? 115.727 138.520 148.113 1.00 1.31  ? 570 ARG B NE  1 
ATOM 5808 C CZ  . ARG B 1 570 ? 115.487 139.820 148.002 1.00 0.91  ? 570 ARG B CZ  1 
ATOM 5809 N NH1 . ARG B 1 570 ? 115.255 140.574 149.063 1.00 1.38  ? 570 ARG B NH1 1 
ATOM 5810 N NH2 . ARG B 1 570 ? 115.479 140.377 146.795 1.00 0.00  ? 570 ARG B NH2 1 
ATOM 5811 N N   . PHE B 1 571 ? 115.868 134.615 153.502 1.00 1.50  ? 571 PHE B N   1 
ATOM 5812 C CA  . PHE B 1 571 ? 115.279 134.393 154.819 1.00 2.73  ? 571 PHE B CA  1 
ATOM 5813 C C   . PHE B 1 571 ? 116.047 135.150 155.893 1.00 2.79  ? 571 PHE B C   1 
ATOM 5814 O O   . PHE B 1 571 ? 115.443 135.764 156.788 1.00 0.00  ? 571 PHE B O   1 
ATOM 5815 C CB  . PHE B 1 571 ? 115.243 132.898 155.135 1.00 2.75  ? 571 PHE B CB  1 
ATOM 5816 C CG  . PHE B 1 571 ? 114.166 132.150 154.407 1.00 0.86  ? 571 PHE B CG  1 
ATOM 5817 C CD1 . PHE B 1 571 ? 112.872 132.126 154.896 1.00 0.57  ? 571 PHE B CD1 1 
ATOM 5818 C CD2 . PHE B 1 571 ? 114.446 131.472 153.235 1.00 3.95  ? 571 PHE B CD2 1 
ATOM 5819 C CE1 . PHE B 1 571 ? 111.879 131.439 154.229 1.00 0.77  ? 571 PHE B CE1 1 
ATOM 5820 C CE2 . PHE B 1 571 ? 113.456 130.785 152.564 1.00 2.50  ? 571 PHE B CE2 1 
ATOM 5821 C CZ  . PHE B 1 571 ? 112.171 130.768 153.062 1.00 2.91  ? 571 PHE B CZ  1 
ATOM 5822 N N   . ALA B 1 572 ? 117.383 135.130 155.814 1.00 5.20  ? 572 ALA B N   1 
ATOM 5823 C CA  . ALA B 1 572 ? 118.174 135.909 156.765 1.00 2.18  ? 572 ALA B CA  1 
ATOM 5824 C C   . ALA B 1 572 ? 117.815 137.394 156.707 1.00 2.43  ? 572 ALA B C   1 
ATOM 5825 O O   . ALA B 1 572 ? 117.690 138.054 157.746 1.00 5.73  ? 572 ALA B O   1 
ATOM 5826 C CB  . ALA B 1 572 ? 119.665 135.704 156.501 1.00 0.51  ? 572 ALA B CB  1 
ATOM 5827 N N   . TRP B 1 573 ? 117.625 137.930 155.499 1.00 0.00  ? 573 TRP B N   1 
ATOM 5828 C CA  . TRP B 1 573 ? 117.317 139.348 155.337 1.00 0.00  ? 573 TRP B CA  1 
ATOM 5829 C C   . TRP B 1 573 ? 115.937 139.693 155.882 1.00 0.00  ? 573 TRP B C   1 
ATOM 5830 O O   . TRP B 1 573 ? 115.762 140.738 156.519 1.00 0.00  ? 573 TRP B O   1 
ATOM 5831 C CB  . TRP B 1 573 ? 117.420 139.732 153.863 1.00 1.48  ? 573 TRP B CB  1 
ATOM 5832 C CG  . TRP B 1 573 ? 116.743 141.018 153.520 1.00 1.34  ? 573 TRP B CG  1 
ATOM 5833 C CD1 . TRP B 1 573 ? 117.198 142.275 153.777 1.00 0.00  ? 573 TRP B CD1 1 
ATOM 5834 C CD2 . TRP B 1 573 ? 115.486 141.174 152.852 1.00 2.01  ? 573 TRP B CD2 1 
ATOM 5835 N NE1 . TRP B 1 573 ? 116.308 143.206 153.307 1.00 0.03  ? 573 TRP B NE1 1 
ATOM 5836 C CE2 . TRP B 1 573 ? 115.246 142.557 152.736 1.00 1.57  ? 573 TRP B CE2 1 
ATOM 5837 C CE3 . TRP B 1 573 ? 114.542 140.280 152.339 1.00 3.56  ? 573 TRP B CE3 1 
ATOM 5838 C CZ2 . TRP B 1 573 ? 114.100 143.068 152.128 1.00 0.76  ? 573 TRP B CZ2 1 
ATOM 5839 C CZ3 . TRP B 1 573 ? 113.403 140.789 151.737 1.00 2.57  ? 573 TRP B CZ3 1 
ATOM 5840 C CH2 . TRP B 1 573 ? 113.193 142.170 151.636 1.00 1.18  ? 573 TRP B CH2 1 
ATOM 5841 N N   . THR B 1 574 ? 114.939 138.847 155.616 1.00 0.95  ? 574 THR B N   1 
ATOM 5842 C CA  . THR B 1 574 ? 113.610 139.107 156.162 1.00 2.05  ? 574 THR B CA  1 
ATOM 5843 C C   . THR B 1 574 ? 113.637 139.094 157.686 1.00 6.98  ? 574 THR B C   1 
ATOM 5844 O O   . THR B 1 574 ? 113.053 139.974 158.336 1.00 4.07  ? 574 THR B O   1 
ATOM 5845 C CB  . THR B 1 574 ? 112.599 138.089 155.634 1.00 2.22  ? 574 THR B CB  1 
ATOM 5846 O OG1 . THR B 1 574 ? 113.203 136.793 155.574 1.00 6.30  ? 574 THR B OG1 1 
ATOM 5847 C CG2 . THR B 1 574 ? 112.112 138.486 154.248 1.00 4.62  ? 574 THR B CG2 1 
ATOM 5848 N N   . ILE B 1 575 ? 114.344 138.125 158.277 1.00 3.09  ? 575 ILE B N   1 
ATOM 5849 C CA  . ILE B 1 575 ? 114.413 138.092 159.734 1.00 1.69  ? 575 ILE B CA  1 
ATOM 5850 C C   . ILE B 1 575 ? 115.168 139.306 160.275 1.00 3.00  ? 575 ILE B C   1 
ATOM 5851 O O   . ILE B 1 575 ? 114.824 139.827 161.342 1.00 6.31  ? 575 ILE B O   1 
ATOM 5852 C CB  . ILE B 1 575 ? 115.012 136.758 160.227 1.00 3.48  ? 575 ILE B CB  1 
ATOM 5853 C CG1 . ILE B 1 575 ? 114.335 136.324 161.528 1.00 7.02  ? 575 ILE B CG1 1 
ATOM 5854 C CG2 . ILE B 1 575 ? 116.505 136.861 160.465 1.00 0.32  ? 575 ILE B CG2 1 
ATOM 5855 C CD1 . ILE B 1 575 ? 112.828 136.381 161.489 1.00 5.47  ? 575 ILE B CD1 1 
ATOM 5856 N N   . GLN B 1 576 ? 116.186 139.795 159.557 1.00 2.63  ? 576 GLN B N   1 
ATOM 5857 C CA  . GLN B 1 576 ? 116.952 140.925 160.077 1.00 2.97  ? 576 GLN B CA  1 
ATOM 5858 C C   . GLN B 1 576 ? 116.155 142.223 159.971 1.00 1.34  ? 576 GLN B C   1 
ATOM 5859 O O   . GLN B 1 576 ? 116.230 143.077 160.863 1.00 3.79  ? 576 GLN B O   1 
ATOM 5860 C CB  . GLN B 1 576 ? 118.311 141.010 159.364 1.00 0.32  ? 576 GLN B CB  1 
ATOM 5861 C CG  . GLN B 1 576 ? 119.210 142.221 159.689 1.00 2.24  ? 576 GLN B CG  1 
ATOM 5862 C CD  . GLN B 1 576 ? 118.747 143.534 159.098 1.00 5.63  ? 576 GLN B CD  1 
ATOM 5863 O OE1 . GLN B 1 576 ? 118.724 144.564 159.771 1.00 5.71  ? 576 GLN B OE1 1 
ATOM 5864 N NE2 . GLN B 1 576 ? 118.437 143.515 157.815 1.00 8.30  ? 576 GLN B NE2 1 
ATOM 5865 N N   . ILE B 1 577 ? 115.376 142.384 158.895 1.00 2.22  ? 577 ILE B N   1 
ATOM 5866 C CA  . ILE B 1 577 ? 114.450 143.513 158.814 1.00 3.47  ? 577 ILE B CA  1 
ATOM 5867 C C   . ILE B 1 577 ? 113.443 143.450 159.954 1.00 5.47  ? 577 ILE B C   1 
ATOM 5868 O O   . ILE B 1 577 ? 113.122 144.471 160.575 1.00 7.52  ? 577 ILE B O   1 
ATOM 5869 C CB  . ILE B 1 577 ? 113.748 143.560 157.440 1.00 4.18  ? 577 ILE B CB  1 
ATOM 5870 C CG1 . ILE B 1 577 ? 114.432 144.543 156.485 1.00 4.28  ? 577 ILE B CG1 1 
ATOM 5871 C CG2 . ILE B 1 577 ? 112.296 143.984 157.582 1.00 0.70  ? 577 ILE B CG2 1 
ATOM 5872 C CD1 . ILE B 1 577 ? 115.898 144.378 156.332 1.00 1.17  ? 577 ILE B CD1 1 
ATOM 5873 N N   . SER B 1 578 ? 112.933 142.252 160.256 1.00 3.16  ? 578 SER B N   1 
ATOM 5874 C CA  . SER B 1 578 ? 111.991 142.126 161.364 1.00 3.72  ? 578 SER B CA  1 
ATOM 5875 C C   . SER B 1 578 ? 112.640 142.505 162.692 1.00 6.00  ? 578 SER B C   1 
ATOM 5876 O O   . SER B 1 578 ? 112.019 143.176 163.524 1.00 4.60  ? 578 SER B O   1 
ATOM 5877 C CB  . SER B 1 578 ? 111.438 140.703 161.429 1.00 5.16  ? 578 SER B CB  1 
ATOM 5878 O OG  . SER B 1 578 ? 110.586 140.434 160.332 1.00 6.19  ? 578 SER B OG  1 
ATOM 5879 N N   . ILE B 1 579 ? 113.885 142.081 162.910 1.00 4.90  ? 579 ILE B N   1 
ATOM 5880 C CA  . ILE B 1 579 ? 114.542 142.323 164.191 1.00 3.34  ? 579 ILE B CA  1 
ATOM 5881 C C   . ILE B 1 579 ? 114.894 143.798 164.370 1.00 2.54  ? 579 ILE B C   1 
ATOM 5882 O O   . ILE B 1 579 ? 114.683 144.366 165.446 1.00 6.62  ? 579 ILE B O   1 
ATOM 5883 C CB  . ILE B 1 579 ? 115.782 141.419 164.327 1.00 3.05  ? 579 ILE B CB  1 
ATOM 5884 C CG1 . ILE B 1 579 ? 115.381 140.052 164.883 1.00 2.30  ? 579 ILE B CG1 1 
ATOM 5885 C CG2 . ILE B 1 579 ? 116.830 142.066 165.222 1.00 2.06  ? 579 ILE B CG2 1 
ATOM 5886 C CD1 . ILE B 1 579 ? 116.394 138.964 164.617 1.00 3.00  ? 579 ILE B CD1 1 
ATOM 5887 N N   . THR B 1 580 ? 115.443 144.442 163.339 1.00 0.92  ? 580 THR B N   1 
ATOM 5888 C CA  . THR B 1 580 ? 115.944 145.805 163.500 1.00 0.69  ? 580 THR B CA  1 
ATOM 5889 C C   . THR B 1 580 ? 114.848 146.819 163.814 1.00 7.22  ? 580 THR B C   1 
ATOM 5890 O O   . THR B 1 580 ? 115.051 147.683 164.674 1.00 10.13 ? 580 THR B O   1 
ATOM 5891 C CB  . THR B 1 580 ? 116.706 146.237 162.244 1.00 4.53  ? 580 THR B CB  1 
ATOM 5892 O OG1 . THR B 1 580 ? 117.894 145.446 162.112 1.00 6.15  ? 580 THR B OG1 1 
ATOM 5893 C CG2 . THR B 1 580 ? 117.096 147.708 162.322 1.00 3.44  ? 580 THR B CG2 1 
ATOM 5894 N N   . SER B 1 581 ? 113.693 146.728 163.157 1.00 9.97  ? 581 SER B N   1 
ATOM 5895 C CA  . SER B 1 581 ? 112.629 147.710 163.307 1.00 6.23  ? 581 SER B CA  1 
ATOM 5896 C C   . SER B 1 581 ? 111.671 147.375 164.446 1.00 9.29  ? 581 SER B C   1 
ATOM 5897 O O   . SER B 1 581 ? 110.703 148.109 164.668 1.00 9.47  ? 581 SER B O   1 
ATOM 5898 C CB  . SER B 1 581 ? 111.854 147.842 161.995 1.00 5.93  ? 581 SER B CB  1 
ATOM 5899 O OG  . SER B 1 581 ? 111.178 149.084 161.923 1.00 6.78  ? 581 SER B OG  1 
ATOM 5900 N N   . THR B 1 582 ? 111.928 146.294 165.181 1.00 5.52  ? 582 THR B N   1 
ATOM 5901 C CA  . THR B 1 582 ? 110.934 145.756 166.099 1.00 5.77  ? 582 THR B CA  1 
ATOM 5902 C C   . THR B 1 582 ? 111.601 145.060 167.283 1.00 12.47 ? 582 THR B C   1 
ATOM 5903 O O   . THR B 1 582 ? 112.615 144.376 167.119 1.00 17.37 ? 582 THR B O   1 
ATOM 5904 C CB  . THR B 1 582 ? 110.003 144.809 165.331 1.00 6.53  ? 582 THR B CB  1 
ATOM 5905 O OG1 . THR B 1 582 ? 109.053 145.576 164.581 1.00 11.90 ? 582 THR B OG1 1 
ATOM 5906 C CG2 . THR B 1 582 ? 109.268 143.867 166.250 1.00 9.27  ? 582 THR B CG2 1 
ATOM 5907 N N   . THR B 1 583 ? 111.031 145.216 168.479 1.00 8.73  ? 583 THR B N   1 
ATOM 5908 C CA  . THR B 1 583 ? 111.644 144.744 169.718 1.00 7.38  ? 583 THR B CA  1 
ATOM 5909 C C   . THR B 1 583 ? 111.538 143.219 169.810 1.00 9.78  ? 583 THR B C   1 
ATOM 5910 O O   . THR B 1 583 ? 111.847 142.621 170.846 1.00 16.17 ? 583 THR B O   1 
ATOM 5911 C CB  . THR B 1 583 ? 110.978 145.449 170.913 1.00 5.83  ? 583 THR B CB  1 
ATOM 5912 O OG1 . THR B 1 583 ? 111.067 146.866 170.726 1.00 10.14 ? 583 THR B OG1 1 
ATOM 5913 C CG2 . THR B 1 583 ? 111.688 145.136 172.226 1.00 5.34  ? 583 THR B CG2 1 
ATOM 5914 N N   . LEU B 1 584 ? 111.122 142.584 168.711 1.00 4.50  ? 584 LEU B N   1 
ATOM 5915 C CA  . LEU B 1 584 ? 110.908 141.142 168.609 1.00 7.87  ? 584 LEU B CA  1 
ATOM 5916 C C   . LEU B 1 584 ? 111.944 140.308 169.356 1.00 8.24  ? 584 LEU B C   1 
ATOM 5917 O O   . LEU B 1 584 ? 111.584 139.389 170.099 1.00 13.90 ? 584 LEU B O   1 
ATOM 5918 C CB  . LEU B 1 584 ? 110.893 140.728 167.136 1.00 7.94  ? 584 LEU B CB  1 
ATOM 5919 C CG  . LEU B 1 584 ? 109.758 141.266 166.264 1.00 7.00  ? 584 LEU B CG  1 
ATOM 5920 C CD1 . LEU B 1 584 ? 109.977 140.881 164.811 1.00 10.12 ? 584 LEU B CD1 1 
ATOM 5921 C CD2 . LEU B 1 584 ? 108.418 140.746 166.762 1.00 7.23  ? 584 LEU B CD2 1 
ATOM 5922 N N   . LEU B 1 585 ? 113.228 140.616 169.176 1.00 8.46  ? 585 LEU B N   1 
ATOM 5923 C CA  . LEU B 1 585 ? 114.291 139.858 169.822 1.00 6.22  ? 585 LEU B CA  1 
ATOM 5924 C C   . LEU B 1 585 ? 115.166 140.799 170.632 1.00 8.31  ? 585 LEU B C   1 
ATOM 5925 O O   . LEU B 1 585 ? 116.219 141.229 170.136 1.00 9.06  ? 585 LEU B O   1 
ATOM 5926 C CB  . LEU B 1 585 ? 115.127 139.121 168.783 1.00 5.39  ? 585 LEU B CB  1 
ATOM 5927 C CG  . LEU B 1 585 ? 115.706 137.765 169.185 1.00 9.48  ? 585 LEU B CG  1 
ATOM 5928 C CD1 . LEU B 1 585 ? 114.615 136.858 169.723 1.00 8.20  ? 585 LEU B CD1 1 
ATOM 5929 C CD2 . LEU B 1 585 ? 116.403 137.118 167.999 1.00 7.47  ? 585 LEU B CD2 1 
ATOM 5930 N N   . PRO B 1 586 ? 114.792 141.135 171.866 1.00 5.37  ? 586 PRO B N   1 
ATOM 5931 C CA  . PRO B 1 586 ? 115.512 142.170 172.629 1.00 7.51  ? 586 PRO B CA  1 
ATOM 5932 C C   . PRO B 1 586 ? 116.863 141.759 173.201 1.00 10.52 ? 586 PRO B C   1 
ATOM 5933 O O   . PRO B 1 586 ? 117.567 142.631 173.723 1.00 10.80 ? 586 PRO B O   1 
ATOM 5934 C CB  . PRO B 1 586 ? 114.525 142.461 173.766 1.00 10.46 ? 586 PRO B CB  1 
ATOM 5935 C CG  . PRO B 1 586 ? 113.871 141.146 174.000 1.00 9.95  ? 586 PRO B CG  1 
ATOM 5936 C CD  . PRO B 1 586 ? 113.643 140.602 172.618 1.00 7.66  ? 586 PRO B CD  1 
ATOM 5937 N N   . HIS B 1 587 ? 117.248 140.485 173.122 1.00 10.53 ? 587 HIS B N   1 
ATOM 5938 C CA  . HIS B 1 587 ? 118.510 140.033 173.698 1.00 5.84  ? 587 HIS B CA  1 
ATOM 5939 C C   . HIS B 1 587 ? 119.537 139.695 172.627 1.00 10.84 ? 587 HIS B C   1 
ATOM 5940 O O   . HIS B 1 587 ? 120.641 140.250 172.649 1.00 13.27 ? 587 HIS B O   1 
ATOM 5941 C CB  . HIS B 1 587 ? 118.278 138.829 174.623 1.00 8.03  ? 587 HIS B CB  1 
ATOM 5942 C CG  . HIS B 1 587 ? 117.339 137.803 174.068 1.00 10.23 ? 587 HIS B CG  1 
ATOM 5943 N ND1 . HIS B 1 587 ? 115.992 138.037 173.894 1.00 8.49  ? 587 HIS B ND1 1 
ATOM 5944 C CD2 . HIS B 1 587 ? 117.556 136.533 173.652 1.00 9.84  ? 587 HIS B CD2 1 
ATOM 5945 C CE1 . HIS B 1 587 ? 115.420 136.957 173.393 1.00 9.84  ? 587 HIS B CE1 1 
ATOM 5946 N NE2 . HIS B 1 587 ? 116.348 136.030 173.236 1.00 9.65  ? 587 HIS B NE2 1 
ATOM 5947 N N   . SER B 1 588 ? 119.173 138.830 171.676 1.00 9.95  ? 588 SER B N   1 
ATOM 5948 C CA  . SER B 1 588 ? 120.146 138.386 170.642 1.00 3.67  ? 588 SER B CA  1 
ATOM 5949 C C   . SER B 1 588 ? 120.055 139.271 169.391 1.00 6.31  ? 588 SER B C   1 
ATOM 5950 O O   . SER B 1 588 ? 121.101 139.473 168.738 1.00 8.87  ? 588 SER B O   1 
ATOM 5951 C CB  . SER B 1 588 ? 119.941 136.934 170.291 1.00 7.45  ? 588 SER B CB  1 
ATOM 5952 O OG  . SER B 1 588 ? 118.667 136.727 169.696 1.00 9.18  ? 588 SER B OG  1 
ATOM 5953 N N   . GLY B 1 589 ? 118.861 139.781 169.075 1.00 11.40 ? 589 GLY B N   1 
ATOM 5954 C CA  . GLY B 1 589 ? 118.669 140.590 167.853 1.00 7.66  ? 589 GLY B CA  1 
ATOM 5955 C C   . GLY B 1 589 ? 119.854 141.488 167.549 1.00 7.30  ? 589 GLY B C   1 
ATOM 5956 O O   . GLY B 1 589 ? 120.333 141.450 166.398 1.00 10.87 ? 589 GLY B O   1 
ATOM 5957 N N   . ASP B 1 590 ? 120.304 142.282 168.526 1.00 6.82  ? 590 ASP B N   1 
ATOM 5958 C CA  . ASP B 1 590 ? 121.424 143.241 168.311 1.00 8.05  ? 590 ASP B CA  1 
ATOM 5959 C C   . ASP B 1 590 ? 122.533 142.595 167.474 1.00 3.20  ? 590 ASP B C   1 
ATOM 5960 O O   . ASP B 1 590 ? 122.802 143.092 166.358 1.00 5.01  ? 590 ASP B O   1 
ATOM 5961 C CB  . ASP B 1 590 ? 121.977 143.745 169.635 1.00 6.53  ? 590 ASP B CB  1 
ATOM 5962 C CG  . ASP B 1 590 ? 123.064 144.804 169.531 1.00 6.08  ? 590 ASP B CG  1 
ATOM 5963 O OD1 . ASP B 1 590 ? 123.400 145.187 168.391 1.00 13.84 ? 590 ASP B OD1 1 
ATOM 5964 O OD2 . ASP B 1 590 ? 123.568 145.236 170.589 1.00 9.11  ? 590 ASP B OD2 1 
ATOM 5965 N N   . ILE B 1 591 ? 123.165 141.544 168.001 1.00 2.98  ? 591 ILE B N   1 
ATOM 5966 C CA  . ILE B 1 591 ? 124.311 140.902 167.289 1.00 4.38  ? 591 ILE B CA  1 
ATOM 5967 C C   . ILE B 1 591 ? 123.824 140.345 165.942 1.00 4.39  ? 591 ILE B C   1 
ATOM 5968 O O   . ILE B 1 591 ? 124.503 140.589 164.925 1.00 2.46  ? 591 ILE B O   1 
ATOM 5969 C CB  . ILE B 1 591 ? 124.949 139.804 168.160 1.00 3.59  ? 591 ILE B CB  1 
ATOM 5970 C CG1 . ILE B 1 591 ? 125.609 140.387 169.410 1.00 5.10  ? 591 ILE B CG1 1 
ATOM 5971 C CG2 . ILE B 1 591 ? 125.927 138.964 167.340 1.00 5.39  ? 591 ILE B CG2 1 
ATOM 5972 C CD1 . ILE B 1 591 ? 126.024 139.349 170.437 1.00 4.79  ? 591 ILE B CD1 1 
ATOM 5973 N N   . ILE B 1 592 ? 122.707 139.613 165.948 1.00 3.26  ? 592 ILE B N   1 
ATOM 5974 C CA  . ILE B 1 592 ? 122.152 139.037 164.687 1.00 4.32  ? 592 ILE B CA  1 
ATOM 5975 C C   . ILE B 1 592 ? 122.205 140.117 163.597 1.00 2.35  ? 592 ILE B C   1 
ATOM 5976 O O   . ILE B 1 592 ? 122.792 139.851 162.527 1.00 3.57  ? 592 ILE B O   1 
ATOM 5977 C CB  . ILE B 1 592 ? 120.717 138.529 164.907 1.00 7.41  ? 592 ILE B CB  1 
ATOM 5978 C CG1 . ILE B 1 592 ? 120.650 137.533 166.061 1.00 5.31  ? 592 ILE B CG1 1 
ATOM 5979 C CG2 . ILE B 1 592 ? 120.137 137.945 163.618 1.00 2.87  ? 592 ILE B CG2 1 
ATOM 5980 C CD1 . ILE B 1 592 ? 119.454 136.603 166.005 1.00 3.54  ? 592 ILE B CD1 1 
ATOM 5981 N N   . ALA B 1 593 ? 121.621 141.287 163.868 1.00 5.70  ? 593 ALA B N   1 
ATOM 5982 C CA  . ALA B 1 593 ? 121.595 142.357 162.874 1.00 0.95  ? 593 ALA B CA  1 
ATOM 5983 C C   . ALA B 1 593 ? 123.000 142.713 162.398 1.00 1.42  ? 593 ALA B C   1 
ATOM 5984 O O   . ALA B 1 593 ? 123.232 142.877 161.192 1.00 2.28  ? 593 ALA B O   1 
ATOM 5985 C CB  . ALA B 1 593 ? 120.894 143.587 163.447 1.00 1.24  ? 593 ALA B CB  1 
ATOM 5986 N N   . THR B 1 594 ? 123.948 142.833 163.332 1.00 1.88  ? 594 THR B N   1 
ATOM 5987 C CA  . THR B 1 594 ? 125.319 143.177 162.971 1.00 0.52  ? 594 THR B CA  1 
ATOM 5988 C C   . THR B 1 594 ? 125.978 142.069 162.163 1.00 0.98  ? 594 THR B C   1 
ATOM 5989 O O   . THR B 1 594 ? 126.814 142.350 161.298 1.00 5.19  ? 594 THR B O   1 
ATOM 5990 C CB  . THR B 1 594 ? 126.135 143.483 164.232 1.00 3.52  ? 594 THR B CB  1 
ATOM 5991 O OG1 . THR B 1 594 ? 125.495 144.529 164.972 1.00 1.40  ? 594 THR B OG1 1 
ATOM 5992 C CG2 . THR B 1 594 ? 127.549 143.921 163.882 1.00 0.00  ? 594 THR B CG2 1 
ATOM 5993 N N   . VAL B 1 595 ? 125.632 140.810 162.433 1.00 0.52  ? 595 VAL B N   1 
ATOM 5994 C CA  . VAL B 1 595 ? 126.141 139.726 161.600 1.00 2.69  ? 595 VAL B CA  1 
ATOM 5995 C C   . VAL B 1 595 ? 125.485 139.741 160.220 1.00 2.27  ? 595 VAL B C   1 
ATOM 5996 O O   . VAL B 1 595 ? 126.159 139.570 159.198 1.00 2.00  ? 595 VAL B O   1 
ATOM 5997 C CB  . VAL B 1 595 ? 125.943 138.374 162.311 1.00 2.49  ? 595 VAL B CB  1 
ATOM 5998 C CG1 . VAL B 1 595 ? 126.075 137.227 161.323 1.00 1.02  ? 595 VAL B CG1 1 
ATOM 5999 C CG2 . VAL B 1 595 ? 126.946 138.220 163.441 1.00 0.11  ? 595 VAL B CG2 1 
ATOM 6000 N N   . PHE B 1 596 ? 124.171 139.962 160.167 1.00 1.64  ? 596 PHE B N   1 
ATOM 6001 C CA  . PHE B 1 596 ? 123.397 139.742 158.952 1.00 1.21  ? 596 PHE B CA  1 
ATOM 6002 C C   . PHE B 1 596 ? 123.535 140.870 157.936 1.00 0.00  ? 596 PHE B C   1 
ATOM 6003 O O   . PHE B 1 596 ? 123.459 140.609 156.731 1.00 1.02  ? 596 PHE B O   1 
ATOM 6004 C CB  . PHE B 1 596 ? 121.922 139.542 159.309 1.00 1.17  ? 596 PHE B CB  1 
ATOM 6005 C CG  . PHE B 1 596 ? 121.582 138.141 159.741 1.00 3.07  ? 596 PHE B CG  1 
ATOM 6006 C CD1 . PHE B 1 596 ? 122.574 137.265 160.152 1.00 3.45  ? 596 PHE B CD1 1 
ATOM 6007 C CD2 . PHE B 1 596 ? 120.269 137.701 159.742 1.00 4.32  ? 596 PHE B CD2 1 
ATOM 6008 C CE1 . PHE B 1 596 ? 122.264 135.980 160.549 1.00 0.41  ? 596 PHE B CE1 1 
ATOM 6009 C CE2 . PHE B 1 596 ? 119.954 136.414 160.137 1.00 3.82  ? 596 PHE B CE2 1 
ATOM 6010 C CZ  . PHE B 1 596 ? 120.952 135.554 160.542 1.00 0.00  ? 596 PHE B CZ  1 
ATOM 6011 N N   . ALA B 1 597 ? 123.711 142.117 158.383 1.00 0.00  ? 597 ALA B N   1 
ATOM 6012 C CA  . ALA B 1 597 ? 123.792 143.229 157.433 1.00 1.17  ? 597 ALA B CA  1 
ATOM 6013 C C   . ALA B 1 597 ? 124.927 143.077 156.424 1.00 1.08  ? 597 ALA B C   1 
ATOM 6014 O O   . ALA B 1 597 ? 124.674 143.253 155.217 1.00 0.00  ? 597 ALA B O   1 
ATOM 6015 C CB  . ALA B 1 597 ? 123.889 144.556 158.195 1.00 0.00  ? 597 ALA B CB  1 
ATOM 6016 N N   . PRO B 1 598 ? 126.170 142.764 156.815 1.00 0.91  ? 598 PRO B N   1 
ATOM 6017 C CA  . PRO B 1 598 ? 127.189 142.483 155.791 1.00 0.60  ? 598 PRO B CA  1 
ATOM 6018 C C   . PRO B 1 598 ? 126.834 141.295 154.921 1.00 0.00  ? 598 PRO B C   1 
ATOM 6019 O O   . PRO B 1 598 ? 127.175 141.282 153.734 1.00 4.17  ? 598 PRO B O   1 
ATOM 6020 C CB  . PRO B 1 598 ? 128.462 142.227 156.614 1.00 1.14  ? 598 PRO B CB  1 
ATOM 6021 C CG  . PRO B 1 598 ? 128.179 142.795 157.960 1.00 1.95  ? 598 PRO B CG  1 
ATOM 6022 C CD  . PRO B 1 598 ? 126.721 142.605 158.172 1.00 0.00  ? 598 PRO B CD  1 
ATOM 6023 N N   . LEU B 1 599 ? 126.142 140.297 155.478 1.00 0.36  ? 599 LEU B N   1 
ATOM 6024 C CA  . LEU B 1 599 ? 125.687 139.169 154.672 1.00 2.03  ? 599 LEU B CA  1 
ATOM 6025 C C   . LEU B 1 599 ? 124.670 139.611 153.626 1.00 0.88  ? 599 LEU B C   1 
ATOM 6026 O O   . LEU B 1 599 ? 124.688 139.123 152.492 1.00 0.00  ? 599 LEU B O   1 
ATOM 6027 C CB  . LEU B 1 599 ? 125.102 138.080 155.571 1.00 0.00  ? 599 LEU B CB  1 
ATOM 6028 C CG  . LEU B 1 599 ? 126.097 137.289 156.424 1.00 0.51  ? 599 LEU B CG  1 
ATOM 6029 C CD1 . LEU B 1 599 ? 125.384 136.228 157.248 1.00 0.15  ? 599 LEU B CD1 1 
ATOM 6030 C CD2 . LEU B 1 599 ? 127.180 136.665 155.557 1.00 0.90  ? 599 LEU B CD2 1 
ATOM 6031 N N   . GLU B 1 600 ? 123.771 140.531 153.985 1.00 0.00  ? 600 GLU B N   1 
ATOM 6032 C CA  . GLU B 1 600 ? 122.813 141.034 153.003 1.00 1.80  ? 600 GLU B CA  1 
ATOM 6033 C C   . GLU B 1 600 ? 123.504 141.878 151.937 1.00 5.01  ? 600 GLU B C   1 
ATOM 6034 O O   . GLU B 1 600 ? 123.128 141.831 150.759 1.00 0.00  ? 600 GLU B O   1 
ATOM 6035 C CB  . GLU B 1 600 ? 121.703 141.827 153.697 1.00 0.00  ? 600 GLU B CB  1 
ATOM 6036 C CG  . GLU B 1 600 ? 120.955 142.806 152.790 1.00 0.30  ? 600 GLU B CG  1 
ATOM 6037 C CD  . GLU B 1 600 ? 119.927 142.139 151.876 1.00 2.03  ? 600 GLU B CD  1 
ATOM 6038 O OE1 . GLU B 1 600 ? 120.029 140.924 151.613 1.00 1.83  ? 600 GLU B OE1 1 
ATOM 6039 O OE2 . GLU B 1 600 ? 119.012 142.846 151.407 1.00 6.24  ? 600 GLU B OE2 1 
ATOM 6040 N N   . VAL B 1 601 ? 124.519 142.654 152.327 1.00 0.00  ? 601 VAL B N   1 
ATOM 6041 C CA  . VAL B 1 601 ? 125.309 143.379 151.333 1.00 0.00  ? 601 VAL B CA  1 
ATOM 6042 C C   . VAL B 1 601 ? 125.983 142.399 150.378 1.00 0.00  ? 601 VAL B C   1 
ATOM 6043 O O   . VAL B 1 601 ? 126.023 142.619 149.161 1.00 0.00  ? 601 VAL B O   1 
ATOM 6044 C CB  . VAL B 1 601 ? 126.332 144.301 152.026 1.00 0.72  ? 601 VAL B CB  1 
ATOM 6045 C CG1 . VAL B 1 601 ? 127.253 144.951 151.002 1.00 1.67  ? 601 VAL B CG1 1 
ATOM 6046 C CG2 . VAL B 1 601 ? 125.621 145.363 152.846 1.00 0.00  ? 601 VAL B CG2 1 
ATOM 6047 N N   . PHE B 1 602 ? 126.505 141.294 150.916 1.00 0.00  ? 602 PHE B N   1 
ATOM 6048 C CA  . PHE B 1 602 ? 127.097 140.251 150.083 1.00 0.60  ? 602 PHE B CA  1 
ATOM 6049 C C   . PHE B 1 602 ? 126.062 139.628 149.148 1.00 0.00  ? 602 PHE B C   1 
ATOM 6050 O O   . PHE B 1 602 ? 126.365 139.319 147.988 1.00 0.00  ? 602 PHE B O   1 
ATOM 6051 C CB  . PHE B 1 602 ? 127.737 139.188 150.979 1.00 0.00  ? 602 PHE B CB  1 
ATOM 6052 C CG  . PHE B 1 602 ? 128.294 138.013 150.233 1.00 0.00  ? 602 PHE B CG  1 
ATOM 6053 C CD1 . PHE B 1 602 ? 129.528 138.092 149.612 1.00 2.32  ? 602 PHE B CD1 1 
ATOM 6054 C CD2 . PHE B 1 602 ? 127.587 136.826 150.158 1.00 2.62  ? 602 PHE B CD2 1 
ATOM 6055 C CE1 . PHE B 1 602 ? 130.044 137.013 148.928 1.00 0.00  ? 602 PHE B CE1 1 
ATOM 6056 C CE2 . PHE B 1 602 ? 128.097 135.743 149.474 1.00 1.74  ? 602 PHE B CE2 1 
ATOM 6057 C CZ  . PHE B 1 602 ? 129.328 135.837 148.858 1.00 1.82  ? 602 PHE B CZ  1 
ATOM 6058 N N   . ARG B 1 603 ? 124.838 139.421 149.641 1.00 0.00  ? 603 ARG B N   1 
ATOM 6059 C CA  . ARG B 1 603 ? 123.774 138.887 148.794 1.00 1.68  ? 603 ARG B CA  1 
ATOM 6060 C C   . ARG B 1 603 ? 123.443 139.839 147.651 1.00 0.00  ? 603 ARG B C   1 
ATOM 6061 O O   . ARG B 1 603 ? 123.237 139.404 146.515 1.00 0.00  ? 603 ARG B O   1 
ATOM 6062 C CB  . ARG B 1 603 ? 122.517 138.599 149.618 1.00 0.36  ? 603 ARG B CB  1 
ATOM 6063 C CG  . ARG B 1 603 ? 121.551 137.645 148.929 1.00 0.00  ? 603 ARG B CG  1 
ATOM 6064 C CD  . ARG B 1 603 ? 120.101 137.838 149.365 1.00 0.00  ? 603 ARG B CD  1 
ATOM 6065 N NE  . ARG B 1 603 ? 119.648 139.219 149.250 1.00 3.43  ? 603 ARG B NE  1 
ATOM 6066 C CZ  . ARG B 1 603 ? 119.024 139.717 148.192 1.00 0.00  ? 603 ARG B CZ  1 
ATOM 6067 N NH1 . ARG B 1 603 ? 118.790 138.981 147.118 1.00 0.00  ? 603 ARG B NH1 1 
ATOM 6068 N NH2 . ARG B 1 603 ? 118.630 140.987 148.209 1.00 0.00  ? 603 ARG B NH2 1 
ATOM 6069 N N   . ARG B 1 604 ? 123.374 141.142 147.940 1.00 0.00  ? 604 ARG B N   1 
ATOM 6070 C CA  . ARG B 1 604 ? 123.144 142.126 146.885 1.00 0.00  ? 604 ARG B CA  1 
ATOM 6071 C C   . ARG B 1 604 ? 124.292 142.127 145.882 1.00 0.00  ? 604 ARG B C   1 
ATOM 6072 O O   . ARG B 1 604 ? 124.074 142.266 144.672 1.00 0.00  ? 604 ARG B O   1 
ATOM 6073 C CB  . ARG B 1 604 ? 122.951 143.518 147.491 1.00 0.00  ? 604 ARG B CB  1 
ATOM 6074 C CG  . ARG B 1 604 ? 122.720 144.629 146.470 1.00 0.00  ? 604 ARG B CG  1 
ATOM 6075 C CD  . ARG B 1 604 ? 121.472 144.385 145.638 1.00 0.00  ? 604 ARG B CD  1 
ATOM 6076 N NE  . ARG B 1 604 ? 120.268 144.331 146.459 1.00 0.00  ? 604 ARG B NE  1 
ATOM 6077 C CZ  . ARG B 1 604 ? 119.045 144.138 145.987 1.00 0.00  ? 604 ARG B CZ  1 
ATOM 6078 N NH1 . ARG B 1 604 ? 118.821 143.980 144.692 1.00 0.00  ? 604 ARG B NH1 1 
ATOM 6079 N NH2 . ARG B 1 604 ? 118.020 144.102 146.833 1.00 0.00  ? 604 ARG B NH2 1 
ATOM 6080 N N   . PHE B 1 605 ? 125.523 141.967 146.372 1.00 0.00  ? 605 PHE B N   1 
ATOM 6081 C CA  . PHE B 1 605 ? 126.683 141.879 145.492 1.00 0.00  ? 605 PHE B CA  1 
ATOM 6082 C C   . PHE B 1 605 ? 126.582 140.678 144.552 1.00 0.00  ? 605 PHE B C   1 
ATOM 6083 O O   . PHE B 1 605 ? 126.886 140.788 143.360 1.00 0.00  ? 605 PHE B O   1 
ATOM 6084 C CB  . PHE B 1 605 ? 127.956 141.823 146.341 1.00 4.99  ? 605 PHE B CB  1 
ATOM 6085 C CG  . PHE B 1 605 ? 129.107 141.114 145.688 1.00 2.74  ? 605 PHE B CG  1 
ATOM 6086 C CD1 . PHE B 1 605 ? 129.836 141.724 144.680 1.00 0.00  ? 605 PHE B CD1 1 
ATOM 6087 C CD2 . PHE B 1 605 ? 129.479 139.844 146.103 1.00 0.00  ? 605 PHE B CD2 1 
ATOM 6088 C CE1 . PHE B 1 605 ? 130.903 141.076 144.084 1.00 0.00  ? 605 PHE B CE1 1 
ATOM 6089 C CE2 . PHE B 1 605 ? 130.545 139.189 145.512 1.00 0.81  ? 605 PHE B CE2 1 
ATOM 6090 C CZ  . PHE B 1 605 ? 131.260 139.808 144.502 1.00 0.00  ? 605 PHE B CZ  1 
ATOM 6091 N N   . VAL B 1 606 ? 126.153 139.525 145.071 1.00 0.00  ? 606 VAL B N   1 
ATOM 6092 C CA  . VAL B 1 606 ? 125.964 138.349 144.220 1.00 0.00  ? 606 VAL B CA  1 
ATOM 6093 C C   . VAL B 1 606 ? 124.816 138.574 143.239 1.00 0.00  ? 606 VAL B C   1 
ATOM 6094 O O   . VAL B 1 606 ? 124.886 138.171 142.072 1.00 0.00  ? 606 VAL B O   1 
ATOM 6095 C CB  . VAL B 1 606 ? 125.735 137.089 145.080 1.00 0.28  ? 606 VAL B CB  1 
ATOM 6096 C CG1 . VAL B 1 606 ? 125.367 135.893 144.204 1.00 0.00  ? 606 VAL B CG1 1 
ATOM 6097 C CG2 . VAL B 1 606 ? 126.964 136.777 145.914 1.00 0.20  ? 606 VAL B CG2 1 
ATOM 6098 N N   . TRP B 1 607 ? 123.745 139.223 143.701 1.00 0.00  ? 607 TRP B N   1 
ATOM 6099 C CA  . TRP B 1 607 ? 122.579 139.497 142.866 1.00 0.00  ? 607 TRP B CA  1 
ATOM 6100 C C   . TRP B 1 607 ? 122.913 140.436 141.711 1.00 0.00  ? 607 TRP B C   1 
ATOM 6101 O O   . TRP B 1 607 ? 122.296 140.348 140.642 1.00 0.00  ? 607 TRP B O   1 
ATOM 6102 C CB  . TRP B 1 607 ? 121.473 140.071 143.755 1.00 0.00  ? 607 TRP B CB  1 
ATOM 6103 C CG  . TRP B 1 607 ? 120.192 140.497 143.088 1.00 0.00  ? 607 TRP B CG  1 
ATOM 6104 C CD1 . TRP B 1 607 ? 119.037 139.775 143.001 1.00 0.00  ? 607 TRP B CD1 1 
ATOM 6105 C CD2 . TRP B 1 607 ? 119.916 141.764 142.478 1.00 0.00  ? 607 TRP B CD2 1 
ATOM 6106 N NE1 . TRP B 1 607 ? 118.072 140.500 142.350 1.00 0.00  ? 607 TRP B NE1 1 
ATOM 6107 C CE2 . TRP B 1 607 ? 118.584 141.727 142.022 1.00 0.00  ? 607 TRP B CE2 1 
ATOM 6108 C CE3 . TRP B 1 607 ? 120.669 142.923 142.265 1.00 0.00  ? 607 TRP B CE3 1 
ATOM 6109 C CZ2 . TRP B 1 607 ? 117.990 142.801 141.363 1.00 0.00  ? 607 TRP B CZ2 1 
ATOM 6110 C CZ3 . TRP B 1 607 ? 120.077 143.986 141.608 1.00 0.00  ? 607 TRP B CZ3 1 
ATOM 6111 C CH2 . TRP B 1 607 ? 118.751 143.920 141.170 1.00 0.00  ? 607 TRP B CH2 1 
ATOM 6112 N N   . ASN B 1 608 ? 123.875 141.341 141.914 1.00 0.00  ? 608 ASN B N   1 
ATOM 6113 C CA  . ASN B 1 608 ? 124.221 142.310 140.879 1.00 0.00  ? 608 ASN B CA  1 
ATOM 6114 C C   . ASN B 1 608 ? 124.740 141.626 139.616 1.00 6.50  ? 608 ASN B C   1 
ATOM 6115 O O   . ASN B 1 608 ? 124.330 141.980 138.502 1.00 3.63  ? 608 ASN B O   1 
ATOM 6116 C CB  . ASN B 1 608 ? 125.248 143.306 141.419 1.00 2.29  ? 608 ASN B CB  1 
ATOM 6117 C CG  . ASN B 1 608 ? 124.611 144.405 142.252 1.00 0.00  ? 608 ASN B CG  1 
ATOM 6118 O OD1 . ASN B 1 608 ? 123.493 144.835 141.979 1.00 0.00  ? 608 ASN B OD1 1 
ATOM 6119 N ND2 . ASN B 1 608 ? 125.322 144.863 143.272 1.00 0.00  ? 608 ASN B ND2 1 
ATOM 6120 N N   . PHE B 1 609 ? 125.624 140.633 139.773 1.00 0.79  ? 609 PHE B N   1 
ATOM 6121 C CA  . PHE B 1 609 ? 126.138 139.874 138.634 1.00 0.00  ? 609 PHE B CA  1 
ATOM 6122 C C   . PHE B 1 609 ? 125.006 139.369 137.749 1.00 0.00  ? 609 PHE B C   1 
ATOM 6123 O O   . PHE B 1 609 ? 124.922 139.701 136.561 1.00 0.00  ? 609 PHE B O   1 
ATOM 6124 C CB  . PHE B 1 609 ? 126.979 138.687 139.118 1.00 2.30  ? 609 PHE B CB  1 
ATOM 6125 C CG  . PHE B 1 609 ? 128.325 139.063 139.664 1.00 0.28  ? 609 PHE B CG  1 
ATOM 6126 C CD1 . PHE B 1 609 ? 129.218 139.800 138.906 1.00 0.00  ? 609 PHE B CD1 1 
ATOM 6127 C CD2 . PHE B 1 609 ? 128.705 138.662 140.934 1.00 3.43  ? 609 PHE B CD2 1 
ATOM 6128 C CE1 . PHE B 1 609 ? 130.458 140.140 139.406 1.00 0.00  ? 609 PHE B CE1 1 
ATOM 6129 C CE2 . PHE B 1 609 ? 129.943 138.997 141.440 1.00 0.00  ? 609 PHE B CE2 1 
ATOM 6130 C CZ  . PHE B 1 609 ? 130.821 139.739 140.677 1.00 0.13  ? 609 PHE B CZ  1 
ATOM 6131 N N   . PHE B 1 610 ? 124.112 138.570 138.328 1.00 5.23  ? 610 PHE B N   1 
ATOM 6132 C CA  . PHE B 1 610 ? 123.127 137.859 137.528 1.00 0.00  ? 610 PHE B CA  1 
ATOM 6133 C C   . PHE B 1 610 ? 121.994 138.764 137.059 1.00 0.00  ? 610 PHE B C   1 
ATOM 6134 O O   . PHE B 1 610 ? 121.473 138.557 135.959 1.00 0.00  ? 610 PHE B O   1 
ATOM 6135 C CB  . PHE B 1 610 ? 122.606 136.654 138.311 1.00 0.00  ? 610 PHE B CB  1 
ATOM 6136 C CG  . PHE B 1 610 ? 123.691 135.696 138.723 1.00 0.70  ? 610 PHE B CG  1 
ATOM 6137 C CD1 . PHE B 1 610 ? 124.255 134.825 137.802 1.00 2.25  ? 610 PHE B CD1 1 
ATOM 6138 C CD2 . PHE B 1 610 ? 124.171 135.688 140.021 1.00 1.26  ? 610 PHE B CD2 1 
ATOM 6139 C CE1 . PHE B 1 610 ? 125.263 133.954 138.176 1.00 0.30  ? 610 PHE B CE1 1 
ATOM 6140 C CE2 . PHE B 1 610 ? 125.180 134.824 140.396 1.00 1.09  ? 610 PHE B CE2 1 
ATOM 6141 C CZ  . PHE B 1 610 ? 125.724 133.953 139.475 1.00 0.00  ? 610 PHE B CZ  1 
ATOM 6142 N N   . ARG B 1 611 ? 121.623 139.790 137.832 1.00 3.62  ? 611 ARG B N   1 
ATOM 6143 C CA  . ARG B 1 611 ? 120.649 140.752 137.326 1.00 0.09  ? 611 ARG B CA  1 
ATOM 6144 C C   . ARG B 1 611 ? 121.200 141.519 136.128 1.00 3.71  ? 611 ARG B C   1 
ATOM 6145 O O   . ARG B 1 611 ? 120.502 141.688 135.121 1.00 0.00  ? 611 ARG B O   1 
ATOM 6146 C CB  . ARG B 1 611 ? 120.221 141.716 138.433 1.00 0.00  ? 611 ARG B CB  1 
ATOM 6147 C CG  . ARG B 1 611 ? 119.371 142.890 137.952 1.00 0.00  ? 611 ARG B CG  1 
ATOM 6148 C CD  . ARG B 1 611 ? 118.009 142.440 137.428 1.00 0.00  ? 611 ARG B CD  1 
ATOM 6149 N NE  . ARG B 1 611 ? 117.428 143.416 136.512 1.00 0.20  ? 611 ARG B NE  1 
ATOM 6150 C CZ  . ARG B 1 611 ? 116.186 143.876 136.586 1.00 0.57  ? 611 ARG B CZ  1 
ATOM 6151 N NH1 . ARG B 1 611 ? 115.346 143.455 137.517 1.00 1.85  ? 611 ARG B NH1 1 
ATOM 6152 N NH2 . ARG B 1 611 ? 115.777 144.784 135.705 1.00 0.00  ? 611 ARG B NH2 1 
ATOM 6153 N N   . LEU B 1 612 ? 122.455 141.976 136.206 1.00 0.00  ? 612 LEU B N   1 
ATOM 6154 C CA  . LEU B 1 612 ? 123.034 142.692 135.075 1.00 0.00  ? 612 LEU B CA  1 
ATOM 6155 C C   . LEU B 1 612 ? 123.210 141.777 133.869 1.00 0.64  ? 612 LEU B C   1 
ATOM 6156 O O   . LEU B 1 612 ? 123.021 142.210 132.728 1.00 0.00  ? 612 LEU B O   1 
ATOM 6157 C CB  . LEU B 1 612 ? 124.364 143.328 135.473 1.00 0.72  ? 612 LEU B CB  1 
ATOM 6158 C CG  . LEU B 1 612 ? 124.287 144.814 135.833 1.00 0.00  ? 612 LEU B CG  1 
ATOM 6159 C CD1 . LEU B 1 612 ? 123.786 145.626 134.646 1.00 0.00  ? 612 LEU B CD1 1 
ATOM 6160 C CD2 . LEU B 1 612 ? 123.409 145.047 137.068 1.00 0.00  ? 612 LEU B CD2 1 
ATOM 6161 N N   . GLU B 1 613 ? 123.570 140.511 134.097 1.00 2.90  ? 613 GLU B N   1 
ATOM 6162 C CA  . GLU B 1 613 ? 123.692 139.575 132.983 1.00 0.00  ? 613 GLU B CA  1 
ATOM 6163 C C   . GLU B 1 613 ? 122.342 139.319 132.319 1.00 1.06  ? 613 GLU B C   1 
ATOM 6164 O O   . GLU B 1 613 ? 122.248 139.289 131.085 1.00 1.85  ? 613 GLU B O   1 
ATOM 6165 C CB  . GLU B 1 613 ? 124.315 138.264 133.460 1.00 2.55  ? 613 GLU B CB  1 
ATOM 6166 C CG  . GLU B 1 613 ? 123.937 137.059 132.618 1.00 0.00  ? 613 GLU B CG  1 
ATOM 6167 C CD  . GLU B 1 613 ? 124.950 135.942 132.718 1.00 7.75  ? 613 GLU B CD  1 
ATOM 6168 O OE1 . GLU B 1 613 ? 126.161 136.241 132.682 1.00 13.19 ? 613 GLU B OE1 1 
ATOM 6169 O OE2 . GLU B 1 613 ? 124.541 134.768 132.835 1.00 4.84  ? 613 GLU B OE2 1 
ATOM 6170 N N   . ASN B 1 614 ? 121.284 139.133 133.117 1.00 0.06  ? 614 ASN B N   1 
ATOM 6171 C CA  . ASN B 1 614 ? 119.951 138.970 132.546 1.00 0.00  ? 614 ASN B CA  1 
ATOM 6172 C C   . ASN B 1 614 ? 119.534 140.199 131.755 1.00 0.00  ? 614 ASN B C   1 
ATOM 6173 O O   . ASN B 1 614 ? 118.926 140.081 130.686 1.00 0.00  ? 614 ASN B O   1 
ATOM 6174 C CB  . ASN B 1 614 ? 118.923 138.695 133.640 1.00 0.00  ? 614 ASN B CB  1 
ATOM 6175 C CG  . ASN B 1 614 ? 117.595 138.236 133.083 1.00 0.00  ? 614 ASN B CG  1 
ATOM 6176 O OD1 . ASN B 1 614 ? 117.533 137.590 132.038 1.00 1.68  ? 614 ASN B OD1 1 
ATOM 6177 N ND2 . ASN B 1 614 ? 116.517 138.645 133.732 1.00 0.00  ? 614 ASN B ND2 1 
ATOM 6178 N N   . GLU B 1 615 ? 119.831 141.389 132.281 1.00 0.00  ? 615 GLU B N   1 
ATOM 6179 C CA  . GLU B 1 615 ? 119.537 142.619 131.557 1.00 0.00  ? 615 GLU B CA  1 
ATOM 6180 C C   . GLU B 1 615 ? 120.292 142.672 130.236 1.00 2.74  ? 615 GLU B C   1 
ATOM 6181 O O   . GLU B 1 615 ? 119.737 143.080 129.209 1.00 1.60  ? 615 GLU B O   1 
ATOM 6182 C CB  . GLU B 1 615 ? 119.893 143.824 132.425 1.00 2.34  ? 615 GLU B CB  1 
ATOM 6183 C CG  . GLU B 1 615 ? 119.029 145.043 132.197 1.00 1.40  ? 615 GLU B CG  1 
ATOM 6184 C CD  . GLU B 1 615 ? 117.733 144.984 132.976 1.00 1.74  ? 615 GLU B CD  1 
ATOM 6185 O OE1 . GLU B 1 615 ? 116.791 144.317 132.507 1.00 0.13  ? 615 GLU B OE1 1 
ATOM 6186 O OE2 . GLU B 1 615 ? 117.657 145.602 134.055 1.00 3.36  ? 615 GLU B OE2 1 
ATOM 6187 N N   . HIS B 1 616 ? 121.564 142.271 130.248 1.00 3.39  ? 616 HIS B N   1 
ATOM 6188 C CA  . HIS B 1 616 ? 122.372 142.284 129.035 1.00 0.00  ? 616 HIS B CA  1 
ATOM 6189 C C   . HIS B 1 616 ? 121.812 141.331 127.987 1.00 2.99  ? 616 HIS B C   1 
ATOM 6190 O O   . HIS B 1 616 ? 121.739 141.668 126.800 1.00 4.51  ? 616 HIS B O   1 
ATOM 6191 C CB  . HIS B 1 616 ? 123.820 141.922 129.374 1.00 2.77  ? 616 HIS B CB  1 
ATOM 6192 C CG  . HIS B 1 616 ? 124.680 141.670 128.175 1.00 1.55  ? 616 HIS B CG  1 
ATOM 6193 N ND1 . HIS B 1 616 ? 125.253 142.687 127.443 1.00 2.02  ? 616 HIS B ND1 1 
ATOM 6194 C CD2 . HIS B 1 616 ? 125.072 140.516 127.586 1.00 5.85  ? 616 HIS B CD2 1 
ATOM 6195 C CE1 . HIS B 1 616 ? 125.957 142.171 126.453 1.00 3.58  ? 616 HIS B CE1 1 
ATOM 6196 N NE2 . HIS B 1 616 ? 125.864 140.855 126.517 1.00 5.02  ? 616 HIS B NE2 1 
ATOM 6197 N N   . LEU B 1 617 ? 121.403 140.135 128.409 1.00 3.23  ? 617 LEU B N   1 
ATOM 6198 C CA  . LEU B 1 617 ? 120.980 139.120 127.450 1.00 0.52  ? 617 LEU B CA  1 
ATOM 6199 C C   . LEU B 1 617 ? 119.536 139.323 127.007 1.00 2.24  ? 617 LEU B C   1 
ATOM 6200 O O   . LEU B 1 617 ? 119.268 139.596 125.832 1.00 7.89  ? 617 LEU B O   1 
ATOM 6201 C CB  . LEU B 1 617 ? 121.158 137.727 128.053 1.00 2.53  ? 617 LEU B CB  1 
ATOM 6202 C CG  . LEU B 1 617 ? 122.571 137.334 128.474 1.00 5.86  ? 617 LEU B CG  1 
ATOM 6203 C CD1 . LEU B 1 617 ? 122.513 136.106 129.358 1.00 3.83  ? 617 LEU B CD1 1 
ATOM 6204 C CD2 . LEU B 1 617 ? 123.444 137.089 127.256 1.00 2.50  ? 617 LEU B CD2 1 
ATOM 6205 N N   . ASN B 1 618 ? 118.589 139.204 127.936 1.00 5.36  ? 618 ASN B N   1 
ATOM 6206 C CA  . ASN B 1 618 ? 117.173 139.157 127.598 1.00 1.42  ? 618 ASN B CA  1 
ATOM 6207 C C   . ASN B 1 618 ? 116.459 140.493 127.770 1.00 0.00  ? 618 ASN B C   1 
ATOM 6208 O O   . ASN B 1 618 ? 115.257 140.571 127.499 1.00 0.00  ? 618 ASN B O   1 
ATOM 6209 C CB  . ASN B 1 618 ? 116.472 138.083 128.432 1.00 2.51  ? 618 ASN B CB  1 
ATOM 6210 C CG  . ASN B 1 618 ? 117.200 136.752 128.406 1.00 4.92  ? 618 ASN B CG  1 
ATOM 6211 O OD1 . ASN B 1 618 ? 117.975 136.437 129.309 1.00 8.63  ? 618 ASN B OD1 1 
ATOM 6212 N ND2 . ASN B 1 618 ? 116.958 135.966 127.366 1.00 6.12  ? 618 ASN B ND2 1 
ATOM 6213 N N   . ASN B 1 619 ? 117.162 141.542 128.200 1.00 3.31  ? 619 ASN B N   1 
ATOM 6214 C CA  . ASN B 1 619 ? 116.553 142.853 128.451 1.00 3.97  ? 619 ASN B CA  1 
ATOM 6215 C C   . ASN B 1 619 ? 115.359 142.722 129.400 1.00 4.10  ? 619 ASN B C   1 
ATOM 6216 O O   . ASN B 1 619 ? 114.244 143.162 129.112 1.00 5.56  ? 619 ASN B O   1 
ATOM 6217 C CB  . ASN B 1 619 ? 116.155 143.526 127.133 1.00 2.39  ? 619 ASN B CB  1 
ATOM 6218 C CG  . ASN B 1 619 ? 115.677 144.953 127.320 1.00 4.67  ? 619 ASN B CG  1 
ATOM 6219 O OD1 . ASN B 1 619 ? 116.216 145.699 128.136 1.00 8.26  ? 619 ASN B OD1 1 
ATOM 6220 N ND2 . ASN B 1 619 ? 114.662 145.340 126.558 1.00 4.55  ? 619 ASN B ND2 1 
ATOM 6221 N N   . CYS B 1 620 ? 115.611 142.097 130.554 1.00 0.19  ? 620 CYS B N   1 
ATOM 6222 C CA  . CYS B 1 620 ? 114.523 141.666 131.427 1.00 1.91  ? 620 CYS B CA  1 
ATOM 6223 C C   . CYS B 1 620 ? 113.758 142.837 132.029 1.00 1.37  ? 620 CYS B C   1 
ATOM 6224 O O   . CYS B 1 620 ? 112.591 142.686 132.406 1.00 5.08  ? 620 CYS B O   1 
ATOM 6225 C CB  . CYS B 1 620 ? 115.071 140.753 132.529 1.00 4.25  ? 620 CYS B CB  1 
ATOM 6226 S SG  . CYS B 1 620 ? 116.229 141.523 133.685 1.00 4.07  ? 620 CYS B SG  1 
ATOM 6227 N N   . GLY B 1 621 ? 114.386 144.008 132.125 1.00 2.55  ? 621 GLY B N   1 
ATOM 6228 C CA  . GLY B 1 621 ? 113.711 145.173 132.668 1.00 4.01  ? 621 GLY B CA  1 
ATOM 6229 C C   . GLY B 1 621 ? 112.826 145.929 131.700 1.00 2.50  ? 621 GLY B C   1 
ATOM 6230 O O   . GLY B 1 621 ? 112.078 146.808 132.138 1.00 3.97  ? 621 GLY B O   1 
ATOM 6231 N N   . GLU B 1 622 ? 112.891 145.607 130.405 1.00 7.02  ? 622 GLU B N   1 
ATOM 6232 C CA  . GLU B 1 622 ? 112.142 146.311 129.359 1.00 1.24  ? 622 GLU B CA  1 
ATOM 6233 C C   . GLU B 1 622 ? 112.462 147.805 129.338 1.00 5.34  ? 622 GLU B C   1 
ATOM 6234 O O   . GLU B 1 622 ? 111.613 148.630 128.995 1.00 5.97  ? 622 GLU B O   1 
ATOM 6235 C CB  . GLU B 1 622 ? 110.633 146.083 129.499 1.00 0.71  ? 622 GLU B CB  1 
ATOM 6236 C CG  . GLU B 1 622 ? 110.185 144.664 129.176 1.00 5.34  ? 622 GLU B CG  1 
ATOM 6237 C CD  . GLU B 1 622 ? 108.815 144.338 129.742 1.00 9.26  ? 622 GLU B CD  1 
ATOM 6238 O OE1 . GLU B 1 622 ? 108.189 145.235 130.343 1.00 9.30  ? 622 GLU B OE1 1 
ATOM 6239 O OE2 . GLU B 1 622 ? 108.358 143.187 129.581 1.00 13.88 ? 622 GLU B OE2 1 
ATOM 6240 N N   . PHE B 1 623 ? 113.694 148.157 129.709 1.00 1.75  ? 623 PHE B N   1 
ATOM 6241 C CA  . PHE B 1 623 ? 114.140 149.545 129.677 1.00 0.00  ? 623 PHE B CA  1 
ATOM 6242 C C   . PHE B 1 623 ? 114.732 149.930 128.327 1.00 4.62  ? 623 PHE B C   1 
ATOM 6243 O O   . PHE B 1 623 ? 115.011 151.111 128.094 1.00 12.27 ? 623 PHE B O   1 
ATOM 6244 C CB  . PHE B 1 623 ? 115.149 149.780 130.801 1.00 1.07  ? 623 PHE B CB  1 
ATOM 6245 C CG  . PHE B 1 623 ? 114.526 149.830 132.162 1.00 0.68  ? 623 PHE B CG  1 
ATOM 6246 C CD1 . PHE B 1 623 ? 113.799 150.937 132.560 1.00 3.03  ? 623 PHE B CD1 1 
ATOM 6247 C CD2 . PHE B 1 623 ? 114.601 148.744 133.013 1.00 3.53  ? 623 PHE B CD2 1 
ATOM 6248 C CE1 . PHE B 1 623 ? 113.208 150.983 133.802 1.00 2.96  ? 623 PHE B CE1 1 
ATOM 6249 C CE2 . PHE B 1 623 ? 113.995 148.779 134.245 1.00 0.27  ? 623 PHE B CE2 1 
ATOM 6250 C CZ  . PHE B 1 623 ? 113.310 149.906 134.647 1.00 0.00  ? 623 PHE B CZ  1 
ATOM 6251 N N   . ARG B 1 624 ? 114.926 148.962 127.435 1.00 5.06  ? 624 ARG B N   1 
ATOM 6252 C CA  . ARG B 1 624 ? 115.386 149.217 126.076 1.00 5.83  ? 624 ARG B CA  1 
ATOM 6253 C C   . ARG B 1 624 ? 114.201 149.113 125.123 1.00 5.90  ? 624 ARG B C   1 
ATOM 6254 O O   . ARG B 1 624 ? 113.274 148.333 125.363 1.00 7.46  ? 624 ARG B O   1 
ATOM 6255 C CB  . ARG B 1 624 ? 116.486 148.236 125.674 1.00 3.80  ? 624 ARG B CB  1 
ATOM 6256 C CG  . ARG B 1 624 ? 117.772 148.412 126.450 1.00 4.73  ? 624 ARG B CG  1 
ATOM 6257 C CD  . ARG B 1 624 ? 118.852 147.465 125.967 1.00 1.62  ? 624 ARG B CD  1 
ATOM 6258 N NE  . ARG B 1 624 ? 119.605 146.919 127.088 1.00 7.49  ? 624 ARG B NE  1 
ATOM 6259 C CZ  . ARG B 1 624 ? 119.720 145.626 127.354 1.00 5.80  ? 624 ARG B CZ  1 
ATOM 6260 N NH1 . ARG B 1 624 ? 119.193 144.707 126.562 1.00 5.06  ? 624 ARG B NH1 1 
ATOM 6261 N NH2 . ARG B 1 624 ? 120.390 145.245 128.437 1.00 6.22  ? 624 ARG B NH2 1 
ATOM 6262 N N   . ALA B 1 625 ? 114.237 149.896 124.050 1.00 8.87  ? 625 ALA B N   1 
ATOM 6263 C CA  . ALA B 1 625 ? 113.172 149.888 123.052 1.00 8.14  ? 625 ALA B CA  1 
ATOM 6264 C C   . ALA B 1 625 ? 113.313 148.695 122.111 1.00 7.68  ? 625 ALA B C   1 
ATOM 6265 O O   . ALA B 1 625 ? 114.379 148.086 122.019 1.00 13.33 ? 625 ALA B O   1 
ATOM 6266 C CB  . ALA B 1 625 ? 113.175 151.188 122.266 1.00 7.90  ? 625 ALA B CB  1 
# 
