data_9CHU
# 
_entry.id   9CHU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CHU         pdb_00009chu 10.2210/pdb9chu/pdb 
WWPDB D_1000285536 ?            ?                   
EMDB  EMD-45602    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-13 
2 'Structure model' 1 1 2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 2 'Structure model' 'Structure summary'   
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' audit_author        
2 2 'Structure model' citation            
3 2 'Structure model' citation_author     
4 2 'Structure model' em_admin            
5 2 'Structure model' em_author_list      
6 2 'Structure model' pdbx_contact_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_audit_author.name'                    
2  2 'Structure model' '_citation.country'                     
3  2 'Structure model' '_citation.journal_abbrev'              
4  2 'Structure model' '_citation.journal_id_ASTM'             
5  2 'Structure model' '_citation.journal_id_CSD'              
6  2 'Structure model' '_citation.journal_id_ISSN'             
7  2 'Structure model' '_citation.journal_volume'              
8  2 'Structure model' '_citation.page_first'                  
9  2 'Structure model' '_citation.page_last'                   
10 2 'Structure model' '_citation.pdbx_database_id_DOI'        
11 2 'Structure model' '_citation.pdbx_database_id_PubMed'     
12 2 'Structure model' '_citation.title'                       
13 2 'Structure model' '_citation.year'                        
14 2 'Structure model' '_em_admin.last_update'                 
15 2 'Structure model' '_em_author_list.author'                
16 2 'Structure model' '_pdbx_contact_author.email'            
17 2 'Structure model' '_pdbx_contact_author.identifier_ORCID' 
18 2 'Structure model' '_pdbx_contact_author.name_first'       
19 2 'Structure model' '_pdbx_contact_author.name_last'        
20 2 'Structure model' '_pdbx_contact_author.phone'            
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CHU 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of calcineurin fused beta2 adrenergic receptor in norepinephrine bound inactive state' 
_pdbx_database_related.db_id          EMD-45602 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              kobilka@stanford.edu 
_pdbx_contact_author.name_first         Brian 
_pdbx_contact_author.name_last          Kobilka 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5958-3990 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xu, J.'        1 ? 
'Chen, G.'      2 ? 
'Du, Y.'        3 ? 
'Kobilka, B.K.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.USA 
_citation.journal_id_ASTM           PNASA6 
_citation.journal_id_CSD            0040 
_citation.journal_id_ISSN           1091-6490 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            121 
_citation.language                  ? 
_citation.page_first                e2414544121 
_citation.page_last                 e2414544121 
_citation.title                     'Calcineurin-fusion facilitates cryo-EM structure determination of a Family A GPCR.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1073/pnas.2414544121 
_citation.pdbx_database_id_PubMed   39565314 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xu, J.'        1 ?                   
primary 'Chen, G.'      2 ?                   
primary 'Wang, H.'      3 ?                   
primary 'Cao, S.'       4 ?                   
primary 'Heng, J.'      5 ?                   
primary 'Deupi, X.'     6 ?                   
primary 'Du, Y.'        7 0000-0001-8107-6397 
primary 'Kobilka, B.K.' 8 0000-0001-5958-3990 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Beta-2 adrenergic receptor,Calcineurin subunit B type 1' 49197.328 1 ?        ? ?                
;residues 29-336 (Uniprot numbering) of the beta2-AR with the third cytoplasmic domain replaced with residues 16-170 (Uniprot numbering) of calcineurin subunit B
;
2 polymer     man 'Protein phosphatase 3 catalytic subunit alpha'           42627.785 1 3.1.3.16 ? 'residues 1-370' ? 
3 polymer     man 'Peptidyl-prolyl cis-trans isomerase FKBP1A'              11967.705 1 5.2.1.8  ? ?                ? 
4 non-polymer syn Noradrenaline                                             170.186   1 ?        ? ?                ? 
5 non-polymer syn '8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN'                      804.018   1 ?        ? ?                ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 
;CAM-PRP catalytic subunit,Calcineurin A alpha,Calmodulin-dependent calcineurin A subunit alpha isoform,CNA alpha,Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
;
3 'PPIase FKBP1A,12 kDa FK506-binding protein,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEF
WTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEE
TCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNP
LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV
DKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDVKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRK
EVYILLNWIGYVNSGFNPLIYCRSPDFRIAF
;
;DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEF
WTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEE
TCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNP
LVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV
DKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDVKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRK
EVYILLNWIGYVNSGFNPLIYCRSPDFRIAF
;
A ? 
2 'polypeptide(L)' no no 
;SEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDI
DAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT
FKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGN
EKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAV
LKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNI
;
;SEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDI
DAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT
FKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGN
EKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAV
LKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNI
;
B ? 
3 'polypeptide(L)' no no 
;MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPD
YAYGATGHPGIIPPHATLVFDVELLKLE
;
;MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPD
YAYGATGHPGIIPPHATLVFDVELLKLE
;
C ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 Noradrenaline                        E5E 
5 '8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN' FK5 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   GLU n 
1 3   VAL n 
1 4   TRP n 
1 5   VAL n 
1 6   VAL n 
1 7   GLY n 
1 8   MET n 
1 9   GLY n 
1 10  ILE n 
1 11  VAL n 
1 12  MET n 
1 13  SER n 
1 14  LEU n 
1 15  ILE n 
1 16  VAL n 
1 17  LEU n 
1 18  ALA n 
1 19  ILE n 
1 20  VAL n 
1 21  PHE n 
1 22  GLY n 
1 23  ASN n 
1 24  VAL n 
1 25  LEU n 
1 26  VAL n 
1 27  ILE n 
1 28  THR n 
1 29  ALA n 
1 30  ILE n 
1 31  ALA n 
1 32  LYS n 
1 33  PHE n 
1 34  GLU n 
1 35  ARG n 
1 36  LEU n 
1 37  GLN n 
1 38  THR n 
1 39  VAL n 
1 40  THR n 
1 41  ASN n 
1 42  TYR n 
1 43  PHE n 
1 44  ILE n 
1 45  THR n 
1 46  SER n 
1 47  LEU n 
1 48  ALA n 
1 49  CYS n 
1 50  ALA n 
1 51  ASP n 
1 52  LEU n 
1 53  VAL n 
1 54  MET n 
1 55  GLY n 
1 56  LEU n 
1 57  ALA n 
1 58  VAL n 
1 59  VAL n 
1 60  PRO n 
1 61  PHE n 
1 62  GLY n 
1 63  ALA n 
1 64  ALA n 
1 65  HIS n 
1 66  ILE n 
1 67  LEU n 
1 68  MET n 
1 69  LYS n 
1 70  MET n 
1 71  TRP n 
1 72  THR n 
1 73  PHE n 
1 74  GLY n 
1 75  ASN n 
1 76  PHE n 
1 77  TRP n 
1 78  CYS n 
1 79  GLU n 
1 80  PHE n 
1 81  TRP n 
1 82  THR n 
1 83  SER n 
1 84  ILE n 
1 85  ASP n 
1 86  VAL n 
1 87  LEU n 
1 88  CYS n 
1 89  VAL n 
1 90  THR n 
1 91  ALA n 
1 92  SER n 
1 93  ILE n 
1 94  GLU n 
1 95  THR n 
1 96  LEU n 
1 97  CYS n 
1 98  VAL n 
1 99  ILE n 
1 100 ALA n 
1 101 VAL n 
1 102 ASP n 
1 103 ARG n 
1 104 TYR n 
1 105 PHE n 
1 106 ALA n 
1 107 ILE n 
1 108 THR n 
1 109 SER n 
1 110 PRO n 
1 111 PHE n 
1 112 LYS n 
1 113 TYR n 
1 114 GLN n 
1 115 SER n 
1 116 LEU n 
1 117 LEU n 
1 118 THR n 
1 119 LYS n 
1 120 ASN n 
1 121 LYS n 
1 122 ALA n 
1 123 ARG n 
1 124 VAL n 
1 125 ILE n 
1 126 ILE n 
1 127 LEU n 
1 128 MET n 
1 129 VAL n 
1 130 TRP n 
1 131 ILE n 
1 132 VAL n 
1 133 SER n 
1 134 GLY n 
1 135 LEU n 
1 136 THR n 
1 137 SER n 
1 138 PHE n 
1 139 LEU n 
1 140 PRO n 
1 141 ILE n 
1 142 GLN n 
1 143 MET n 
1 144 HIS n 
1 145 TRP n 
1 146 TYR n 
1 147 ARG n 
1 148 ALA n 
1 149 THR n 
1 150 HIS n 
1 151 GLN n 
1 152 GLU n 
1 153 ALA n 
1 154 ILE n 
1 155 ASN n 
1 156 CYS n 
1 157 TYR n 
1 158 ALA n 
1 159 GLU n 
1 160 GLU n 
1 161 THR n 
1 162 CYS n 
1 163 CYS n 
1 164 ASP n 
1 165 PHE n 
1 166 PHE n 
1 167 THR n 
1 168 ASN n 
1 169 GLN n 
1 170 ALA n 
1 171 TYR n 
1 172 ALA n 
1 173 ILE n 
1 174 ALA n 
1 175 SER n 
1 176 SER n 
1 177 ILE n 
1 178 VAL n 
1 179 SER n 
1 180 PHE n 
1 181 TYR n 
1 182 VAL n 
1 183 PRO n 
1 184 LEU n 
1 185 VAL n 
1 186 ILE n 
1 187 MET n 
1 188 VAL n 
1 189 PHE n 
1 190 VAL n 
1 191 TYR n 
1 192 SER n 
1 193 ARG n 
1 194 VAL n 
1 195 PHE n 
1 196 GLN n 
1 197 GLU n 
1 198 ALA n 
1 199 LYS n 
1 200 ARG n 
1 201 GLN n 
1 202 LEU n 
1 203 ASP n 
1 204 ALA n 
1 205 ASP n 
1 206 GLU n 
1 207 ILE n 
1 208 LYS n 
1 209 ARG n 
1 210 LEU n 
1 211 GLY n 
1 212 LYS n 
1 213 ARG n 
1 214 PHE n 
1 215 LYS n 
1 216 LYS n 
1 217 LEU n 
1 218 ASP n 
1 219 LEU n 
1 220 ASP n 
1 221 ASN n 
1 222 SER n 
1 223 GLY n 
1 224 SER n 
1 225 LEU n 
1 226 SER n 
1 227 VAL n 
1 228 GLU n 
1 229 GLU n 
1 230 PHE n 
1 231 MET n 
1 232 SER n 
1 233 LEU n 
1 234 PRO n 
1 235 GLU n 
1 236 LEU n 
1 237 GLN n 
1 238 GLN n 
1 239 ASN n 
1 240 PRO n 
1 241 LEU n 
1 242 VAL n 
1 243 GLN n 
1 244 ARG n 
1 245 VAL n 
1 246 ILE n 
1 247 ASP n 
1 248 ILE n 
1 249 PHE n 
1 250 ASP n 
1 251 THR n 
1 252 ASP n 
1 253 GLY n 
1 254 ASN n 
1 255 GLY n 
1 256 GLU n 
1 257 VAL n 
1 258 ASP n 
1 259 PHE n 
1 260 LYS n 
1 261 GLU n 
1 262 PHE n 
1 263 ILE n 
1 264 GLU n 
1 265 GLY n 
1 266 VAL n 
1 267 SER n 
1 268 GLN n 
1 269 PHE n 
1 270 SER n 
1 271 VAL n 
1 272 LYS n 
1 273 GLY n 
1 274 ASP n 
1 275 LYS n 
1 276 GLU n 
1 277 GLN n 
1 278 LYS n 
1 279 LEU n 
1 280 ARG n 
1 281 PHE n 
1 282 ALA n 
1 283 PHE n 
1 284 ARG n 
1 285 ILE n 
1 286 TYR n 
1 287 ASP n 
1 288 MET n 
1 289 ASP n 
1 290 LYS n 
1 291 ASP n 
1 292 GLY n 
1 293 TYR n 
1 294 ILE n 
1 295 SER n 
1 296 ASN n 
1 297 GLY n 
1 298 GLU n 
1 299 LEU n 
1 300 PHE n 
1 301 GLN n 
1 302 VAL n 
1 303 LEU n 
1 304 LYS n 
1 305 MET n 
1 306 MET n 
1 307 VAL n 
1 308 GLY n 
1 309 ASN n 
1 310 ASN n 
1 311 LEU n 
1 312 LYS n 
1 313 ASP n 
1 314 THR n 
1 315 GLN n 
1 316 LEU n 
1 317 GLN n 
1 318 GLN n 
1 319 ILE n 
1 320 VAL n 
1 321 ASP n 
1 322 LYS n 
1 323 THR n 
1 324 ILE n 
1 325 ILE n 
1 326 ASN n 
1 327 ALA n 
1 328 ASP n 
1 329 LYS n 
1 330 ASP n 
1 331 GLY n 
1 332 ASP n 
1 333 GLY n 
1 334 ARG n 
1 335 ILE n 
1 336 SER n 
1 337 PHE n 
1 338 GLU n 
1 339 GLU n 
1 340 PHE n 
1 341 CYS n 
1 342 ALA n 
1 343 VAL n 
1 344 VAL n 
1 345 GLY n 
1 346 GLY n 
1 347 LEU n 
1 348 ASP n 
1 349 ILE n 
1 350 HIS n 
1 351 LYS n 
1 352 LYS n 
1 353 MET n 
1 354 VAL n 
1 355 VAL n 
1 356 ASP n 
1 357 VAL n 
1 358 LYS n 
1 359 PHE n 
1 360 CYS n 
1 361 LEU n 
1 362 LYS n 
1 363 GLU n 
1 364 HIS n 
1 365 LYS n 
1 366 ALA n 
1 367 LEU n 
1 368 LYS n 
1 369 THR n 
1 370 LEU n 
1 371 GLY n 
1 372 ILE n 
1 373 ILE n 
1 374 MET n 
1 375 GLY n 
1 376 THR n 
1 377 PHE n 
1 378 THR n 
1 379 LEU n 
1 380 CYS n 
1 381 TRP n 
1 382 LEU n 
1 383 PRO n 
1 384 PHE n 
1 385 PHE n 
1 386 ILE n 
1 387 VAL n 
1 388 ASN n 
1 389 ILE n 
1 390 VAL n 
1 391 HIS n 
1 392 VAL n 
1 393 ILE n 
1 394 GLN n 
1 395 ASP n 
1 396 ASN n 
1 397 LEU n 
1 398 ILE n 
1 399 ARG n 
1 400 LYS n 
1 401 GLU n 
1 402 VAL n 
1 403 TYR n 
1 404 ILE n 
1 405 LEU n 
1 406 LEU n 
1 407 ASN n 
1 408 TRP n 
1 409 ILE n 
1 410 GLY n 
1 411 TYR n 
1 412 VAL n 
1 413 ASN n 
1 414 SER n 
1 415 GLY n 
1 416 PHE n 
1 417 ASN n 
1 418 PRO n 
1 419 LEU n 
1 420 ILE n 
1 421 TYR n 
1 422 CYS n 
1 423 ARG n 
1 424 SER n 
1 425 PRO n 
1 426 ASP n 
1 427 PHE n 
1 428 ARG n 
1 429 ILE n 
1 430 ALA n 
1 431 PHE n 
2 1   SER n 
2 2   GLU n 
2 3   PRO n 
2 4   LYS n 
2 5   ALA n 
2 6   ILE n 
2 7   ASP n 
2 8   PRO n 
2 9   LYS n 
2 10  LEU n 
2 11  SER n 
2 12  THR n 
2 13  THR n 
2 14  ASP n 
2 15  ARG n 
2 16  VAL n 
2 17  VAL n 
2 18  LYS n 
2 19  ALA n 
2 20  VAL n 
2 21  PRO n 
2 22  PHE n 
2 23  PRO n 
2 24  PRO n 
2 25  SER n 
2 26  HIS n 
2 27  ARG n 
2 28  LEU n 
2 29  THR n 
2 30  ALA n 
2 31  LYS n 
2 32  GLU n 
2 33  VAL n 
2 34  PHE n 
2 35  ASP n 
2 36  ASN n 
2 37  ASP n 
2 38  GLY n 
2 39  LYS n 
2 40  PRO n 
2 41  ARG n 
2 42  VAL n 
2 43  ASP n 
2 44  ILE n 
2 45  LEU n 
2 46  LYS n 
2 47  ALA n 
2 48  HIS n 
2 49  LEU n 
2 50  MET n 
2 51  LYS n 
2 52  GLU n 
2 53  GLY n 
2 54  ARG n 
2 55  LEU n 
2 56  GLU n 
2 57  GLU n 
2 58  SER n 
2 59  VAL n 
2 60  ALA n 
2 61  LEU n 
2 62  ARG n 
2 63  ILE n 
2 64  ILE n 
2 65  THR n 
2 66  GLU n 
2 67  GLY n 
2 68  ALA n 
2 69  SER n 
2 70  ILE n 
2 71  LEU n 
2 72  ARG n 
2 73  GLN n 
2 74  GLU n 
2 75  LYS n 
2 76  ASN n 
2 77  LEU n 
2 78  LEU n 
2 79  ASP n 
2 80  ILE n 
2 81  ASP n 
2 82  ALA n 
2 83  PRO n 
2 84  VAL n 
2 85  THR n 
2 86  VAL n 
2 87  CYS n 
2 88  GLY n 
2 89  ASP n 
2 90  ILE n 
2 91  HIS n 
2 92  GLY n 
2 93  GLN n 
2 94  PHE n 
2 95  PHE n 
2 96  ASP n 
2 97  LEU n 
2 98  MET n 
2 99  LYS n 
2 100 LEU n 
2 101 PHE n 
2 102 GLU n 
2 103 VAL n 
2 104 GLY n 
2 105 GLY n 
2 106 SER n 
2 107 PRO n 
2 108 ALA n 
2 109 ASN n 
2 110 THR n 
2 111 ARG n 
2 112 TYR n 
2 113 LEU n 
2 114 PHE n 
2 115 LEU n 
2 116 GLY n 
2 117 ASP n 
2 118 TYR n 
2 119 VAL n 
2 120 ASP n 
2 121 ARG n 
2 122 GLY n 
2 123 TYR n 
2 124 PHE n 
2 125 SER n 
2 126 ILE n 
2 127 GLU n 
2 128 CYS n 
2 129 VAL n 
2 130 LEU n 
2 131 TYR n 
2 132 LEU n 
2 133 TRP n 
2 134 ALA n 
2 135 LEU n 
2 136 LYS n 
2 137 ILE n 
2 138 LEU n 
2 139 TYR n 
2 140 PRO n 
2 141 LYS n 
2 142 THR n 
2 143 LEU n 
2 144 PHE n 
2 145 LEU n 
2 146 LEU n 
2 147 ARG n 
2 148 GLY n 
2 149 ASN n 
2 150 HIS n 
2 151 GLU n 
2 152 CYS n 
2 153 ARG n 
2 154 HIS n 
2 155 LEU n 
2 156 THR n 
2 157 GLU n 
2 158 TYR n 
2 159 PHE n 
2 160 THR n 
2 161 PHE n 
2 162 LYS n 
2 163 GLN n 
2 164 GLU n 
2 165 CYS n 
2 166 LYS n 
2 167 ILE n 
2 168 LYS n 
2 169 TYR n 
2 170 SER n 
2 171 GLU n 
2 172 ARG n 
2 173 VAL n 
2 174 TYR n 
2 175 ASP n 
2 176 ALA n 
2 177 CYS n 
2 178 MET n 
2 179 ASP n 
2 180 ALA n 
2 181 PHE n 
2 182 ASP n 
2 183 CYS n 
2 184 LEU n 
2 185 PRO n 
2 186 LEU n 
2 187 ALA n 
2 188 ALA n 
2 189 LEU n 
2 190 MET n 
2 191 ASN n 
2 192 GLN n 
2 193 GLN n 
2 194 PHE n 
2 195 LEU n 
2 196 CYS n 
2 197 VAL n 
2 198 HIS n 
2 199 GLY n 
2 200 GLY n 
2 201 LEU n 
2 202 SER n 
2 203 PRO n 
2 204 GLU n 
2 205 ILE n 
2 206 ASN n 
2 207 THR n 
2 208 LEU n 
2 209 ASP n 
2 210 ASP n 
2 211 ILE n 
2 212 ARG n 
2 213 LYS n 
2 214 LEU n 
2 215 ASP n 
2 216 ARG n 
2 217 PHE n 
2 218 LYS n 
2 219 GLU n 
2 220 PRO n 
2 221 PRO n 
2 222 ALA n 
2 223 TYR n 
2 224 GLY n 
2 225 PRO n 
2 226 MET n 
2 227 CYS n 
2 228 ASP n 
2 229 ILE n 
2 230 LEU n 
2 231 TRP n 
2 232 SER n 
2 233 ASP n 
2 234 PRO n 
2 235 LEU n 
2 236 GLU n 
2 237 ASP n 
2 238 PHE n 
2 239 GLY n 
2 240 ASN n 
2 241 GLU n 
2 242 LYS n 
2 243 THR n 
2 244 GLN n 
2 245 GLU n 
2 246 HIS n 
2 247 PHE n 
2 248 THR n 
2 249 HIS n 
2 250 ASN n 
2 251 THR n 
2 252 VAL n 
2 253 ARG n 
2 254 GLY n 
2 255 CYS n 
2 256 SER n 
2 257 TYR n 
2 258 PHE n 
2 259 TYR n 
2 260 SER n 
2 261 TYR n 
2 262 PRO n 
2 263 ALA n 
2 264 VAL n 
2 265 CYS n 
2 266 ASP n 
2 267 PHE n 
2 268 LEU n 
2 269 GLN n 
2 270 HIS n 
2 271 ASN n 
2 272 ASN n 
2 273 LEU n 
2 274 LEU n 
2 275 SER n 
2 276 ILE n 
2 277 LEU n 
2 278 ARG n 
2 279 ALA n 
2 280 HIS n 
2 281 GLU n 
2 282 ALA n 
2 283 GLN n 
2 284 ASP n 
2 285 ALA n 
2 286 GLY n 
2 287 TYR n 
2 288 ARG n 
2 289 MET n 
2 290 TYR n 
2 291 ARG n 
2 292 LYS n 
2 293 SER n 
2 294 GLN n 
2 295 THR n 
2 296 THR n 
2 297 GLY n 
2 298 PHE n 
2 299 PRO n 
2 300 SER n 
2 301 LEU n 
2 302 ILE n 
2 303 THR n 
2 304 ILE n 
2 305 PHE n 
2 306 SER n 
2 307 ALA n 
2 308 PRO n 
2 309 ASN n 
2 310 TYR n 
2 311 LEU n 
2 312 ASP n 
2 313 VAL n 
2 314 TYR n 
2 315 ASN n 
2 316 ASN n 
2 317 LYS n 
2 318 ALA n 
2 319 ALA n 
2 320 VAL n 
2 321 LEU n 
2 322 LYS n 
2 323 TYR n 
2 324 GLU n 
2 325 ASN n 
2 326 ASN n 
2 327 VAL n 
2 328 MET n 
2 329 ASN n 
2 330 ILE n 
2 331 ARG n 
2 332 GLN n 
2 333 PHE n 
2 334 ASN n 
2 335 CYS n 
2 336 SER n 
2 337 PRO n 
2 338 HIS n 
2 339 PRO n 
2 340 TYR n 
2 341 TRP n 
2 342 LEU n 
2 343 PRO n 
2 344 ASN n 
2 345 PHE n 
2 346 MET n 
2 347 ASP n 
2 348 VAL n 
2 349 PHE n 
2 350 THR n 
2 351 TRP n 
2 352 SER n 
2 353 LEU n 
2 354 PRO n 
2 355 PHE n 
2 356 VAL n 
2 357 GLY n 
2 358 GLU n 
2 359 LYS n 
2 360 VAL n 
2 361 THR n 
2 362 GLU n 
2 363 MET n 
2 364 LEU n 
2 365 VAL n 
2 366 ASN n 
2 367 VAL n 
2 368 LEU n 
2 369 ASN n 
2 370 ILE n 
3 1   MET n 
3 2   GLY n 
3 3   VAL n 
3 4   GLN n 
3 5   VAL n 
3 6   GLU n 
3 7   THR n 
3 8   ILE n 
3 9   SER n 
3 10  PRO n 
3 11  GLY n 
3 12  ASP n 
3 13  GLY n 
3 14  ARG n 
3 15  THR n 
3 16  PHE n 
3 17  PRO n 
3 18  LYS n 
3 19  ARG n 
3 20  GLY n 
3 21  GLN n 
3 22  THR n 
3 23  CYS n 
3 24  VAL n 
3 25  VAL n 
3 26  HIS n 
3 27  TYR n 
3 28  THR n 
3 29  GLY n 
3 30  MET n 
3 31  LEU n 
3 32  GLU n 
3 33  ASP n 
3 34  GLY n 
3 35  LYS n 
3 36  LYS n 
3 37  PHE n 
3 38  ASP n 
3 39  SER n 
3 40  SER n 
3 41  ARG n 
3 42  ASP n 
3 43  ARG n 
3 44  ASN n 
3 45  LYS n 
3 46  PRO n 
3 47  PHE n 
3 48  LYS n 
3 49  PHE n 
3 50  MET n 
3 51  LEU n 
3 52  GLY n 
3 53  LYS n 
3 54  GLN n 
3 55  GLU n 
3 56  VAL n 
3 57  ILE n 
3 58  ARG n 
3 59  GLY n 
3 60  TRP n 
3 61  GLU n 
3 62  GLU n 
3 63  GLY n 
3 64  VAL n 
3 65  ALA n 
3 66  GLN n 
3 67  MET n 
3 68  SER n 
3 69  VAL n 
3 70  GLY n 
3 71  GLN n 
3 72  ARG n 
3 73  ALA n 
3 74  LYS n 
3 75  LEU n 
3 76  THR n 
3 77  ILE n 
3 78  SER n 
3 79  PRO n 
3 80  ASP n 
3 81  TYR n 
3 82  ALA n 
3 83  TYR n 
3 84  GLY n 
3 85  ALA n 
3 86  THR n 
3 87  GLY n 
3 88  HIS n 
3 89  PRO n 
3 90  GLY n 
3 91  ILE n 
3 92  ILE n 
3 93  PRO n 
3 94  PRO n 
3 95  HIS n 
3 96  ALA n 
3 97  THR n 
3 98  LEU n 
3 99  VAL n 
3 100 PHE n 
3 101 ASP n 
3 102 VAL n 
3 103 GLU n 
3 104 LEU n 
3 105 LEU n 
3 106 LYS n 
3 107 LEU n 
3 108 GLU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   202 human         ? 'ADRB2, ADRB2R, B2AR'   ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda'                     7108   ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 203 357 human         ? 'PPP3R1, CNA2, CNB'     ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda'                     7108   ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 358 431 human         ? 'ADRB2, ADRB2R, B2AR'   ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda'                     7108   ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   370 'house mouse' ? 'Ppp3ca, Calna'         ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda'                     7108   ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   108 human         ? 'FKBP1A, FKBP1, FKBP12' ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
;Escherichia coli 'BL21-Gold(DE3)pLysS AG'
;
866768 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ?    'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                             ?    'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ?    'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ?    'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                             ?    'C3 H7 N O2 S'   121.158 
E5E non-polymer         . Noradrenaline                        ?    'C8 H12 N O3 1'  170.186 
FK5 non-polymer         . '8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN' K506 'C44 H69 N O12'  804.018 
GLN 'L-peptide linking' y GLUTAMINE                            ?    'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ?    'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                              ?    'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                            ?    'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                           ?    'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                              ?    'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                               ?    'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                           ?    'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ?    'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                              ?    'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                               ?    'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                            ?    'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ?    'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                             ?    'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                               ?    'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   29  ?   ?   ?   A . n 
A 1 2   GLU 2   30  ?   ?   ?   A . n 
A 1 3   VAL 3   31  ?   ?   ?   A . n 
A 1 4   TRP 4   32  32  TRP TRP A . n 
A 1 5   VAL 5   33  33  VAL VAL A . n 
A 1 6   VAL 6   34  34  VAL VAL A . n 
A 1 7   GLY 7   35  35  GLY GLY A . n 
A 1 8   MET 8   36  36  MET MET A . n 
A 1 9   GLY 9   37  37  GLY GLY A . n 
A 1 10  ILE 10  38  38  ILE ILE A . n 
A 1 11  VAL 11  39  39  VAL VAL A . n 
A 1 12  MET 12  40  40  MET MET A . n 
A 1 13  SER 13  41  41  SER SER A . n 
A 1 14  LEU 14  42  42  LEU LEU A . n 
A 1 15  ILE 15  43  43  ILE ILE A . n 
A 1 16  VAL 16  44  44  VAL VAL A . n 
A 1 17  LEU 17  45  45  LEU LEU A . n 
A 1 18  ALA 18  46  46  ALA ALA A . n 
A 1 19  ILE 19  47  47  ILE ILE A . n 
A 1 20  VAL 20  48  48  VAL VAL A . n 
A 1 21  PHE 21  49  49  PHE PHE A . n 
A 1 22  GLY 22  50  50  GLY GLY A . n 
A 1 23  ASN 23  51  51  ASN ASN A . n 
A 1 24  VAL 24  52  52  VAL VAL A . n 
A 1 25  LEU 25  53  53  LEU LEU A . n 
A 1 26  VAL 26  54  54  VAL VAL A . n 
A 1 27  ILE 27  55  55  ILE ILE A . n 
A 1 28  THR 28  56  56  THR THR A . n 
A 1 29  ALA 29  57  57  ALA ALA A . n 
A 1 30  ILE 30  58  58  ILE ILE A . n 
A 1 31  ALA 31  59  59  ALA ALA A . n 
A 1 32  LYS 32  60  60  LYS LYS A . n 
A 1 33  PHE 33  61  61  PHE PHE A . n 
A 1 34  GLU 34  62  62  GLU GLU A . n 
A 1 35  ARG 35  63  63  ARG ARG A . n 
A 1 36  LEU 36  64  64  LEU LEU A . n 
A 1 37  GLN 37  65  65  GLN GLN A . n 
A 1 38  THR 38  66  66  THR THR A . n 
A 1 39  VAL 39  67  67  VAL VAL A . n 
A 1 40  THR 40  68  68  THR THR A . n 
A 1 41  ASN 41  69  69  ASN ASN A . n 
A 1 42  TYR 42  70  70  TYR TYR A . n 
A 1 43  PHE 43  71  71  PHE PHE A . n 
A 1 44  ILE 44  72  72  ILE ILE A . n 
A 1 45  THR 45  73  73  THR THR A . n 
A 1 46  SER 46  74  74  SER SER A . n 
A 1 47  LEU 47  75  75  LEU LEU A . n 
A 1 48  ALA 48  76  76  ALA ALA A . n 
A 1 49  CYS 49  77  77  CYS CYS A . n 
A 1 50  ALA 50  78  78  ALA ALA A . n 
A 1 51  ASP 51  79  79  ASP ASP A . n 
A 1 52  LEU 52  80  80  LEU LEU A . n 
A 1 53  VAL 53  81  81  VAL VAL A . n 
A 1 54  MET 54  82  82  MET MET A . n 
A 1 55  GLY 55  83  83  GLY GLY A . n 
A 1 56  LEU 56  84  84  LEU LEU A . n 
A 1 57  ALA 57  85  85  ALA ALA A . n 
A 1 58  VAL 58  86  86  VAL VAL A . n 
A 1 59  VAL 59  87  87  VAL VAL A . n 
A 1 60  PRO 60  88  88  PRO PRO A . n 
A 1 61  PHE 61  89  89  PHE PHE A . n 
A 1 62  GLY 62  90  90  GLY GLY A . n 
A 1 63  ALA 63  91  91  ALA ALA A . n 
A 1 64  ALA 64  92  92  ALA ALA A . n 
A 1 65  HIS 65  93  93  HIS HIS A . n 
A 1 66  ILE 66  94  94  ILE ILE A . n 
A 1 67  LEU 67  95  95  LEU LEU A . n 
A 1 68  MET 68  96  96  MET MET A . n 
A 1 69  LYS 69  97  97  LYS LYS A . n 
A 1 70  MET 70  98  98  MET MET A . n 
A 1 71  TRP 71  99  99  TRP TRP A . n 
A 1 72  THR 72  100 100 THR THR A . n 
A 1 73  PHE 73  101 101 PHE PHE A . n 
A 1 74  GLY 74  102 102 GLY GLY A . n 
A 1 75  ASN 75  103 103 ASN ASN A . n 
A 1 76  PHE 76  104 104 PHE PHE A . n 
A 1 77  TRP 77  105 105 TRP TRP A . n 
A 1 78  CYS 78  106 106 CYS CYS A . n 
A 1 79  GLU 79  107 107 GLU GLU A . n 
A 1 80  PHE 80  108 108 PHE PHE A . n 
A 1 81  TRP 81  109 109 TRP TRP A . n 
A 1 82  THR 82  110 110 THR THR A . n 
A 1 83  SER 83  111 111 SER SER A . n 
A 1 84  ILE 84  112 112 ILE ILE A . n 
A 1 85  ASP 85  113 113 ASP ASP A . n 
A 1 86  VAL 86  114 114 VAL VAL A . n 
A 1 87  LEU 87  115 115 LEU LEU A . n 
A 1 88  CYS 88  116 116 CYS CYS A . n 
A 1 89  VAL 89  117 117 VAL VAL A . n 
A 1 90  THR 90  118 118 THR THR A . n 
A 1 91  ALA 91  119 119 ALA ALA A . n 
A 1 92  SER 92  120 120 SER SER A . n 
A 1 93  ILE 93  121 121 ILE ILE A . n 
A 1 94  GLU 94  122 122 GLU GLU A . n 
A 1 95  THR 95  123 123 THR THR A . n 
A 1 96  LEU 96  124 124 LEU LEU A . n 
A 1 97  CYS 97  125 125 CYS CYS A . n 
A 1 98  VAL 98  126 126 VAL VAL A . n 
A 1 99  ILE 99  127 127 ILE ILE A . n 
A 1 100 ALA 100 128 128 ALA ALA A . n 
A 1 101 VAL 101 129 129 VAL VAL A . n 
A 1 102 ASP 102 130 130 ASP ASP A . n 
A 1 103 ARG 103 131 131 ARG ARG A . n 
A 1 104 TYR 104 132 132 TYR TYR A . n 
A 1 105 PHE 105 133 133 PHE PHE A . n 
A 1 106 ALA 106 134 134 ALA ALA A . n 
A 1 107 ILE 107 135 135 ILE ILE A . n 
A 1 108 THR 108 136 136 THR THR A . n 
A 1 109 SER 109 137 137 SER SER A . n 
A 1 110 PRO 110 138 138 PRO PRO A . n 
A 1 111 PHE 111 139 139 PHE PHE A . n 
A 1 112 LYS 112 140 140 LYS LYS A . n 
A 1 113 TYR 113 141 141 TYR TYR A . n 
A 1 114 GLN 114 142 142 GLN GLN A . n 
A 1 115 SER 115 143 143 SER SER A . n 
A 1 116 LEU 116 144 144 LEU LEU A . n 
A 1 117 LEU 117 145 145 LEU LEU A . n 
A 1 118 THR 118 146 146 THR THR A . n 
A 1 119 LYS 119 147 147 LYS LYS A . n 
A 1 120 ASN 120 148 148 ASN ASN A . n 
A 1 121 LYS 121 149 149 LYS LYS A . n 
A 1 122 ALA 122 150 150 ALA ALA A . n 
A 1 123 ARG 123 151 151 ARG ARG A . n 
A 1 124 VAL 124 152 152 VAL VAL A . n 
A 1 125 ILE 125 153 153 ILE ILE A . n 
A 1 126 ILE 126 154 154 ILE ILE A . n 
A 1 127 LEU 127 155 155 LEU LEU A . n 
A 1 128 MET 128 156 156 MET MET A . n 
A 1 129 VAL 129 157 157 VAL VAL A . n 
A 1 130 TRP 130 158 158 TRP TRP A . n 
A 1 131 ILE 131 159 159 ILE ILE A . n 
A 1 132 VAL 132 160 160 VAL VAL A . n 
A 1 133 SER 133 161 161 SER SER A . n 
A 1 134 GLY 134 162 162 GLY GLY A . n 
A 1 135 LEU 135 163 163 LEU LEU A . n 
A 1 136 THR 136 164 164 THR THR A . n 
A 1 137 SER 137 165 165 SER SER A . n 
A 1 138 PHE 138 166 166 PHE PHE A . n 
A 1 139 LEU 139 167 167 LEU LEU A . n 
A 1 140 PRO 140 168 168 PRO PRO A . n 
A 1 141 ILE 141 169 169 ILE ILE A . n 
A 1 142 GLN 142 170 170 GLN GLN A . n 
A 1 143 MET 143 171 171 MET MET A . n 
A 1 144 HIS 144 172 172 HIS HIS A . n 
A 1 145 TRP 145 173 173 TRP TRP A . n 
A 1 146 TYR 146 174 174 TYR TYR A . n 
A 1 147 ARG 147 175 175 ARG ARG A . n 
A 1 148 ALA 148 176 176 ALA ALA A . n 
A 1 149 THR 149 177 177 THR THR A . n 
A 1 150 HIS 150 178 178 HIS HIS A . n 
A 1 151 GLN 151 179 179 GLN GLN A . n 
A 1 152 GLU 152 180 180 GLU GLU A . n 
A 1 153 ALA 153 181 181 ALA ALA A . n 
A 1 154 ILE 154 182 182 ILE ILE A . n 
A 1 155 ASN 155 183 183 ASN ASN A . n 
A 1 156 CYS 156 184 184 CYS CYS A . n 
A 1 157 TYR 157 185 185 TYR TYR A . n 
A 1 158 ALA 158 186 186 ALA ALA A . n 
A 1 159 GLU 159 187 187 GLU GLU A . n 
A 1 160 GLU 160 188 188 GLU GLU A . n 
A 1 161 THR 161 189 189 THR THR A . n 
A 1 162 CYS 162 190 190 CYS CYS A . n 
A 1 163 CYS 163 191 191 CYS CYS A . n 
A 1 164 ASP 164 192 192 ASP ASP A . n 
A 1 165 PHE 165 193 193 PHE PHE A . n 
A 1 166 PHE 166 194 194 PHE PHE A . n 
A 1 167 THR 167 195 195 THR THR A . n 
A 1 168 ASN 168 196 196 ASN ASN A . n 
A 1 169 GLN 169 197 197 GLN GLN A . n 
A 1 170 ALA 170 198 198 ALA ALA A . n 
A 1 171 TYR 171 199 199 TYR TYR A . n 
A 1 172 ALA 172 200 200 ALA ALA A . n 
A 1 173 ILE 173 201 201 ILE ILE A . n 
A 1 174 ALA 174 202 202 ALA ALA A . n 
A 1 175 SER 175 203 203 SER SER A . n 
A 1 176 SER 176 204 204 SER SER A . n 
A 1 177 ILE 177 205 205 ILE ILE A . n 
A 1 178 VAL 178 206 206 VAL VAL A . n 
A 1 179 SER 179 207 207 SER SER A . n 
A 1 180 PHE 180 208 208 PHE PHE A . n 
A 1 181 TYR 181 209 209 TYR TYR A . n 
A 1 182 VAL 182 210 210 VAL VAL A . n 
A 1 183 PRO 183 211 211 PRO PRO A . n 
A 1 184 LEU 184 212 212 LEU LEU A . n 
A 1 185 VAL 185 213 213 VAL VAL A . n 
A 1 186 ILE 186 214 214 ILE ILE A . n 
A 1 187 MET 187 215 215 MET MET A . n 
A 1 188 VAL 188 216 216 VAL VAL A . n 
A 1 189 PHE 189 217 217 PHE PHE A . n 
A 1 190 VAL 190 218 218 VAL VAL A . n 
A 1 191 TYR 191 219 219 TYR TYR A . n 
A 1 192 SER 192 220 220 SER SER A . n 
A 1 193 ARG 193 221 221 ARG ARG A . n 
A 1 194 VAL 194 222 222 VAL VAL A . n 
A 1 195 PHE 195 223 223 PHE PHE A . n 
A 1 196 GLN 196 224 224 GLN GLN A . n 
A 1 197 GLU 197 225 225 GLU GLU A . n 
A 1 198 ALA 198 226 226 ALA ALA A . n 
A 1 199 LYS 199 227 227 LYS LYS A . n 
A 1 200 ARG 200 228 228 ARG ARG A . n 
A 1 201 GLN 201 229 229 GLN GLN A . n 
A 1 202 LEU 202 230 230 LEU LEU A . n 
A 1 203 ASP 203 231 231 ASP ASP A . n 
A 1 204 ALA 204 232 232 ALA ALA A . n 
A 1 205 ASP 205 233 233 ASP ASP A . n 
A 1 206 GLU 206 234 234 GLU GLU A . n 
A 1 207 ILE 207 235 235 ILE ILE A . n 
A 1 208 LYS 208 236 236 LYS LYS A . n 
A 1 209 ARG 209 237 237 ARG ARG A . n 
A 1 210 LEU 210 238 238 LEU LEU A . n 
A 1 211 GLY 211 239 239 GLY GLY A . n 
A 1 212 LYS 212 240 240 LYS LYS A . n 
A 1 213 ARG 213 241 241 ARG ARG A . n 
A 1 214 PHE 214 242 242 PHE PHE A . n 
A 1 215 LYS 215 243 243 LYS LYS A . n 
A 1 216 LYS 216 244 244 LYS LYS A . n 
A 1 217 LEU 217 245 245 LEU LEU A . n 
A 1 218 ASP 218 246 246 ASP ASP A . n 
A 1 219 LEU 219 247 247 LEU LEU A . n 
A 1 220 ASP 220 248 248 ASP ASP A . n 
A 1 221 ASN 221 249 249 ASN ASN A . n 
A 1 222 SER 222 250 250 SER SER A . n 
A 1 223 GLY 223 251 251 GLY GLY A . n 
A 1 224 SER 224 252 252 SER SER A . n 
A 1 225 LEU 225 253 253 LEU LEU A . n 
A 1 226 SER 226 254 254 SER SER A . n 
A 1 227 VAL 227 255 255 VAL VAL A . n 
A 1 228 GLU 228 256 256 GLU GLU A . n 
A 1 229 GLU 229 257 257 GLU GLU A . n 
A 1 230 PHE 230 258 258 PHE PHE A . n 
A 1 231 MET 231 259 259 MET MET A . n 
A 1 232 SER 232 260 260 SER SER A . n 
A 1 233 LEU 233 261 261 LEU LEU A . n 
A 1 234 PRO 234 262 262 PRO PRO A . n 
A 1 235 GLU 235 263 263 GLU GLU A . n 
A 1 236 LEU 236 264 264 LEU LEU A . n 
A 1 237 GLN 237 265 265 GLN GLN A . n 
A 1 238 GLN 238 266 266 GLN GLN A . n 
A 1 239 ASN 239 267 267 ASN ASN A . n 
A 1 240 PRO 240 268 268 PRO PRO A . n 
A 1 241 LEU 241 269 269 LEU LEU A . n 
A 1 242 VAL 242 270 270 VAL VAL A . n 
A 1 243 GLN 243 271 271 GLN GLN A . n 
A 1 244 ARG 244 272 272 ARG ARG A . n 
A 1 245 VAL 245 273 273 VAL VAL A . n 
A 1 246 ILE 246 274 274 ILE ILE A . n 
A 1 247 ASP 247 275 275 ASP ASP A . n 
A 1 248 ILE 248 276 276 ILE ILE A . n 
A 1 249 PHE 249 277 277 PHE PHE A . n 
A 1 250 ASP 250 278 278 ASP ASP A . n 
A 1 251 THR 251 279 279 THR THR A . n 
A 1 252 ASP 252 280 280 ASP ASP A . n 
A 1 253 GLY 253 281 281 GLY GLY A . n 
A 1 254 ASN 254 282 282 ASN ASN A . n 
A 1 255 GLY 255 283 283 GLY GLY A . n 
A 1 256 GLU 256 284 284 GLU GLU A . n 
A 1 257 VAL 257 285 285 VAL VAL A . n 
A 1 258 ASP 258 286 286 ASP ASP A . n 
A 1 259 PHE 259 287 287 PHE PHE A . n 
A 1 260 LYS 260 288 288 LYS LYS A . n 
A 1 261 GLU 261 289 289 GLU GLU A . n 
A 1 262 PHE 262 290 290 PHE PHE A . n 
A 1 263 ILE 263 291 291 ILE ILE A . n 
A 1 264 GLU 264 292 292 GLU GLU A . n 
A 1 265 GLY 265 293 293 GLY GLY A . n 
A 1 266 VAL 266 294 294 VAL VAL A . n 
A 1 267 SER 267 295 295 SER SER A . n 
A 1 268 GLN 268 296 296 GLN GLN A . n 
A 1 269 PHE 269 297 297 PHE PHE A . n 
A 1 270 SER 270 298 298 SER SER A . n 
A 1 271 VAL 271 299 299 VAL VAL A . n 
A 1 272 LYS 272 300 300 LYS LYS A . n 
A 1 273 GLY 273 301 301 GLY GLY A . n 
A 1 274 ASP 274 302 302 ASP ASP A . n 
A 1 275 LYS 275 303 303 LYS LYS A . n 
A 1 276 GLU 276 304 304 GLU GLU A . n 
A 1 277 GLN 277 305 305 GLN GLN A . n 
A 1 278 LYS 278 306 306 LYS LYS A . n 
A 1 279 LEU 279 307 307 LEU LEU A . n 
A 1 280 ARG 280 308 308 ARG ARG A . n 
A 1 281 PHE 281 309 309 PHE PHE A . n 
A 1 282 ALA 282 310 310 ALA ALA A . n 
A 1 283 PHE 283 311 311 PHE PHE A . n 
A 1 284 ARG 284 312 312 ARG ARG A . n 
A 1 285 ILE 285 313 313 ILE ILE A . n 
A 1 286 TYR 286 314 314 TYR TYR A . n 
A 1 287 ASP 287 315 315 ASP ASP A . n 
A 1 288 MET 288 316 316 MET MET A . n 
A 1 289 ASP 289 317 317 ASP ASP A . n 
A 1 290 LYS 290 318 318 LYS LYS A . n 
A 1 291 ASP 291 319 319 ASP ASP A . n 
A 1 292 GLY 292 320 320 GLY GLY A . n 
A 1 293 TYR 293 321 321 TYR TYR A . n 
A 1 294 ILE 294 322 322 ILE ILE A . n 
A 1 295 SER 295 323 323 SER SER A . n 
A 1 296 ASN 296 324 324 ASN ASN A . n 
A 1 297 GLY 297 325 325 GLY GLY A . n 
A 1 298 GLU 298 326 326 GLU GLU A . n 
A 1 299 LEU 299 327 327 LEU LEU A . n 
A 1 300 PHE 300 328 328 PHE PHE A . n 
A 1 301 GLN 301 329 329 GLN GLN A . n 
A 1 302 VAL 302 330 330 VAL VAL A . n 
A 1 303 LEU 303 331 331 LEU LEU A . n 
A 1 304 LYS 304 332 332 LYS LYS A . n 
A 1 305 MET 305 333 333 MET MET A . n 
A 1 306 MET 306 334 334 MET MET A . n 
A 1 307 VAL 307 335 335 VAL VAL A . n 
A 1 308 GLY 308 336 336 GLY GLY A . n 
A 1 309 ASN 309 337 337 ASN ASN A . n 
A 1 310 ASN 310 338 338 ASN ASN A . n 
A 1 311 LEU 311 339 339 LEU LEU A . n 
A 1 312 LYS 312 340 340 LYS LYS A . n 
A 1 313 ASP 313 341 341 ASP ASP A . n 
A 1 314 THR 314 342 342 THR THR A . n 
A 1 315 GLN 315 343 343 GLN GLN A . n 
A 1 316 LEU 316 344 344 LEU LEU A . n 
A 1 317 GLN 317 345 345 GLN GLN A . n 
A 1 318 GLN 318 346 346 GLN GLN A . n 
A 1 319 ILE 319 347 347 ILE ILE A . n 
A 1 320 VAL 320 348 348 VAL VAL A . n 
A 1 321 ASP 321 349 349 ASP ASP A . n 
A 1 322 LYS 322 350 350 LYS LYS A . n 
A 1 323 THR 323 351 351 THR THR A . n 
A 1 324 ILE 324 352 352 ILE ILE A . n 
A 1 325 ILE 325 353 353 ILE ILE A . n 
A 1 326 ASN 326 354 354 ASN ASN A . n 
A 1 327 ALA 327 355 355 ALA ALA A . n 
A 1 328 ASP 328 356 356 ASP ASP A . n 
A 1 329 LYS 329 357 357 LYS LYS A . n 
A 1 330 ASP 330 358 358 ASP ASP A . n 
A 1 331 GLY 331 359 359 GLY GLY A . n 
A 1 332 ASP 332 360 360 ASP ASP A . n 
A 1 333 GLY 333 361 361 GLY GLY A . n 
A 1 334 ARG 334 362 362 ARG ARG A . n 
A 1 335 ILE 335 363 363 ILE ILE A . n 
A 1 336 SER 336 364 364 SER SER A . n 
A 1 337 PHE 337 365 365 PHE PHE A . n 
A 1 338 GLU 338 366 366 GLU GLU A . n 
A 1 339 GLU 339 367 367 GLU GLU A . n 
A 1 340 PHE 340 368 368 PHE PHE A . n 
A 1 341 CYS 341 369 369 CYS CYS A . n 
A 1 342 ALA 342 370 370 ALA ALA A . n 
A 1 343 VAL 343 371 371 VAL VAL A . n 
A 1 344 VAL 344 372 372 VAL VAL A . n 
A 1 345 GLY 345 373 373 GLY GLY A . n 
A 1 346 GLY 346 374 374 GLY GLY A . n 
A 1 347 LEU 347 375 375 LEU LEU A . n 
A 1 348 ASP 348 376 376 ASP ASP A . n 
A 1 349 ILE 349 377 377 ILE ILE A . n 
A 1 350 HIS 350 378 378 HIS HIS A . n 
A 1 351 LYS 351 379 379 LYS LYS A . n 
A 1 352 LYS 352 380 380 LYS LYS A . n 
A 1 353 MET 353 381 381 MET MET A . n 
A 1 354 VAL 354 382 382 VAL VAL A . n 
A 1 355 VAL 355 383 383 VAL VAL A . n 
A 1 356 ASP 356 384 384 ASP ASP A . n 
A 1 357 VAL 357 385 385 VAL VAL A . n 
A 1 358 LYS 358 386 386 LYS LYS A . n 
A 1 359 PHE 359 387 387 PHE PHE A . n 
A 1 360 CYS 360 388 388 CYS CYS A . n 
A 1 361 LEU 361 389 389 LEU LEU A . n 
A 1 362 LYS 362 390 390 LYS LYS A . n 
A 1 363 GLU 363 391 391 GLU GLU A . n 
A 1 364 HIS 364 392 392 HIS HIS A . n 
A 1 365 LYS 365 393 393 LYS LYS A . n 
A 1 366 ALA 366 394 394 ALA ALA A . n 
A 1 367 LEU 367 395 395 LEU LEU A . n 
A 1 368 LYS 368 396 396 LYS LYS A . n 
A 1 369 THR 369 397 397 THR THR A . n 
A 1 370 LEU 370 398 398 LEU LEU A . n 
A 1 371 GLY 371 399 399 GLY GLY A . n 
A 1 372 ILE 372 400 400 ILE ILE A . n 
A 1 373 ILE 373 401 401 ILE ILE A . n 
A 1 374 MET 374 402 402 MET MET A . n 
A 1 375 GLY 375 403 403 GLY GLY A . n 
A 1 376 THR 376 404 404 THR THR A . n 
A 1 377 PHE 377 405 405 PHE PHE A . n 
A 1 378 THR 378 406 406 THR THR A . n 
A 1 379 LEU 379 407 407 LEU LEU A . n 
A 1 380 CYS 380 408 408 CYS CYS A . n 
A 1 381 TRP 381 409 409 TRP TRP A . n 
A 1 382 LEU 382 410 410 LEU LEU A . n 
A 1 383 PRO 383 411 411 PRO PRO A . n 
A 1 384 PHE 384 412 412 PHE PHE A . n 
A 1 385 PHE 385 413 413 PHE PHE A . n 
A 1 386 ILE 386 414 414 ILE ILE A . n 
A 1 387 VAL 387 415 415 VAL VAL A . n 
A 1 388 ASN 388 416 416 ASN ASN A . n 
A 1 389 ILE 389 417 417 ILE ILE A . n 
A 1 390 VAL 390 418 418 VAL VAL A . n 
A 1 391 HIS 391 419 419 HIS HIS A . n 
A 1 392 VAL 392 420 420 VAL VAL A . n 
A 1 393 ILE 393 421 421 ILE ILE A . n 
A 1 394 GLN 394 422 422 GLN GLN A . n 
A 1 395 ASP 395 423 423 ASP ASP A . n 
A 1 396 ASN 396 424 424 ASN ASN A . n 
A 1 397 LEU 397 425 425 LEU LEU A . n 
A 1 398 ILE 398 426 426 ILE ILE A . n 
A 1 399 ARG 399 427 427 ARG ARG A . n 
A 1 400 LYS 400 428 428 LYS LYS A . n 
A 1 401 GLU 401 429 429 GLU GLU A . n 
A 1 402 VAL 402 430 430 VAL VAL A . n 
A 1 403 TYR 403 431 431 TYR TYR A . n 
A 1 404 ILE 404 432 432 ILE ILE A . n 
A 1 405 LEU 405 433 433 LEU LEU A . n 
A 1 406 LEU 406 434 434 LEU LEU A . n 
A 1 407 ASN 407 435 435 ASN ASN A . n 
A 1 408 TRP 408 436 436 TRP TRP A . n 
A 1 409 ILE 409 437 437 ILE ILE A . n 
A 1 410 GLY 410 438 438 GLY GLY A . n 
A 1 411 TYR 411 439 439 TYR TYR A . n 
A 1 412 VAL 412 440 440 VAL VAL A . n 
A 1 413 ASN 413 441 441 ASN ASN A . n 
A 1 414 SER 414 442 442 SER SER A . n 
A 1 415 GLY 415 443 443 GLY GLY A . n 
A 1 416 PHE 416 444 444 PHE PHE A . n 
A 1 417 ASN 417 445 445 ASN ASN A . n 
A 1 418 PRO 418 446 446 PRO PRO A . n 
A 1 419 LEU 419 447 447 LEU LEU A . n 
A 1 420 ILE 420 448 448 ILE ILE A . n 
A 1 421 TYR 421 449 449 TYR TYR A . n 
A 1 422 CYS 422 450 450 CYS CYS A . n 
A 1 423 ARG 423 451 451 ARG ARG A . n 
A 1 424 SER 424 452 452 SER SER A . n 
A 1 425 PRO 425 453 453 PRO PRO A . n 
A 1 426 ASP 426 454 454 ASP ASP A . n 
A 1 427 PHE 427 455 455 PHE PHE A . n 
A 1 428 ARG 428 456 456 ARG ARG A . n 
A 1 429 ILE 429 457 457 ILE ILE A . n 
A 1 430 ALA 430 458 458 ALA ALA A . n 
A 1 431 PHE 431 459 459 PHE PHE A . n 
B 2 1   SER 1   1   ?   ?   ?   B . n 
B 2 2   GLU 2   2   ?   ?   ?   B . n 
B 2 3   PRO 3   3   ?   ?   ?   B . n 
B 2 4   LYS 4   4   ?   ?   ?   B . n 
B 2 5   ALA 5   5   ?   ?   ?   B . n 
B 2 6   ILE 6   6   ?   ?   ?   B . n 
B 2 7   ASP 7   7   ?   ?   ?   B . n 
B 2 8   PRO 8   8   ?   ?   ?   B . n 
B 2 9   LYS 9   9   ?   ?   ?   B . n 
B 2 10  LEU 10  10  ?   ?   ?   B . n 
B 2 11  SER 11  11  ?   ?   ?   B . n 
B 2 12  THR 12  12  ?   ?   ?   B . n 
B 2 13  THR 13  13  13  THR THR B . n 
B 2 14  ASP 14  14  14  ASP ASP B . n 
B 2 15  ARG 15  15  15  ARG ARG B . n 
B 2 16  VAL 16  16  16  VAL VAL B . n 
B 2 17  VAL 17  17  17  VAL VAL B . n 
B 2 18  LYS 18  18  18  LYS LYS B . n 
B 2 19  ALA 19  19  19  ALA ALA B . n 
B 2 20  VAL 20  20  20  VAL VAL B . n 
B 2 21  PRO 21  21  21  PRO PRO B . n 
B 2 22  PHE 22  22  22  PHE PHE B . n 
B 2 23  PRO 23  23  23  PRO PRO B . n 
B 2 24  PRO 24  24  24  PRO PRO B . n 
B 2 25  SER 25  25  25  SER SER B . n 
B 2 26  HIS 26  26  26  HIS HIS B . n 
B 2 27  ARG 27  27  27  ARG ARG B . n 
B 2 28  LEU 28  28  28  LEU LEU B . n 
B 2 29  THR 29  29  29  THR THR B . n 
B 2 30  ALA 30  30  30  ALA ALA B . n 
B 2 31  LYS 31  31  31  LYS LYS B . n 
B 2 32  GLU 32  32  32  GLU GLU B . n 
B 2 33  VAL 33  33  33  VAL VAL B . n 
B 2 34  PHE 34  34  34  PHE PHE B . n 
B 2 35  ASP 35  35  35  ASP ASP B . n 
B 2 36  ASN 36  36  ?   ?   ?   B . n 
B 2 37  ASP 37  37  ?   ?   ?   B . n 
B 2 38  GLY 38  38  38  GLY GLY B . n 
B 2 39  LYS 39  39  39  LYS LYS B . n 
B 2 40  PRO 40  40  40  PRO PRO B . n 
B 2 41  ARG 41  41  41  ARG ARG B . n 
B 2 42  VAL 42  42  42  VAL VAL B . n 
B 2 43  ASP 43  43  43  ASP ASP B . n 
B 2 44  ILE 44  44  44  ILE ILE B . n 
B 2 45  LEU 45  45  45  LEU LEU B . n 
B 2 46  LYS 46  46  46  LYS LYS B . n 
B 2 47  ALA 47  47  47  ALA ALA B . n 
B 2 48  HIS 48  48  48  HIS HIS B . n 
B 2 49  LEU 49  49  49  LEU LEU B . n 
B 2 50  MET 50  50  50  MET MET B . n 
B 2 51  LYS 51  51  51  LYS LYS B . n 
B 2 52  GLU 52  52  52  GLU GLU B . n 
B 2 53  GLY 53  53  53  GLY GLY B . n 
B 2 54  ARG 54  54  54  ARG ARG B . n 
B 2 55  LEU 55  55  55  LEU LEU B . n 
B 2 56  GLU 56  56  56  GLU GLU B . n 
B 2 57  GLU 57  57  57  GLU GLU B . n 
B 2 58  SER 58  58  58  SER SER B . n 
B 2 59  VAL 59  59  59  VAL VAL B . n 
B 2 60  ALA 60  60  60  ALA ALA B . n 
B 2 61  LEU 61  61  61  LEU LEU B . n 
B 2 62  ARG 62  62  62  ARG ARG B . n 
B 2 63  ILE 63  63  63  ILE ILE B . n 
B 2 64  ILE 64  64  64  ILE ILE B . n 
B 2 65  THR 65  65  65  THR THR B . n 
B 2 66  GLU 66  66  66  GLU GLU B . n 
B 2 67  GLY 67  67  67  GLY GLY B . n 
B 2 68  ALA 68  68  68  ALA ALA B . n 
B 2 69  SER 69  69  69  SER SER B . n 
B 2 70  ILE 70  70  70  ILE ILE B . n 
B 2 71  LEU 71  71  71  LEU LEU B . n 
B 2 72  ARG 72  72  72  ARG ARG B . n 
B 2 73  GLN 73  73  73  GLN GLN B . n 
B 2 74  GLU 74  74  74  GLU GLU B . n 
B 2 75  LYS 75  75  75  LYS LYS B . n 
B 2 76  ASN 76  76  76  ASN ASN B . n 
B 2 77  LEU 77  77  77  LEU LEU B . n 
B 2 78  LEU 78  78  78  LEU LEU B . n 
B 2 79  ASP 79  79  79  ASP ASP B . n 
B 2 80  ILE 80  80  80  ILE ILE B . n 
B 2 81  ASP 81  81  81  ASP ASP B . n 
B 2 82  ALA 82  82  82  ALA ALA B . n 
B 2 83  PRO 83  83  83  PRO PRO B . n 
B 2 84  VAL 84  84  84  VAL VAL B . n 
B 2 85  THR 85  85  85  THR THR B . n 
B 2 86  VAL 86  86  86  VAL VAL B . n 
B 2 87  CYS 87  87  87  CYS CYS B . n 
B 2 88  GLY 88  88  88  GLY GLY B . n 
B 2 89  ASP 89  89  89  ASP ASP B . n 
B 2 90  ILE 90  90  90  ILE ILE B . n 
B 2 91  HIS 91  91  91  HIS HIS B . n 
B 2 92  GLY 92  92  92  GLY GLY B . n 
B 2 93  GLN 93  93  93  GLN GLN B . n 
B 2 94  PHE 94  94  94  PHE PHE B . n 
B 2 95  PHE 95  95  95  PHE PHE B . n 
B 2 96  ASP 96  96  96  ASP ASP B . n 
B 2 97  LEU 97  97  97  LEU LEU B . n 
B 2 98  MET 98  98  98  MET MET B . n 
B 2 99  LYS 99  99  99  LYS LYS B . n 
B 2 100 LEU 100 100 100 LEU LEU B . n 
B 2 101 PHE 101 101 101 PHE PHE B . n 
B 2 102 GLU 102 102 102 GLU GLU B . n 
B 2 103 VAL 103 103 103 VAL VAL B . n 
B 2 104 GLY 104 104 104 GLY GLY B . n 
B 2 105 GLY 105 105 105 GLY GLY B . n 
B 2 106 SER 106 106 106 SER SER B . n 
B 2 107 PRO 107 107 107 PRO PRO B . n 
B 2 108 ALA 108 108 108 ALA ALA B . n 
B 2 109 ASN 109 109 109 ASN ASN B . n 
B 2 110 THR 110 110 110 THR THR B . n 
B 2 111 ARG 111 111 111 ARG ARG B . n 
B 2 112 TYR 112 112 112 TYR TYR B . n 
B 2 113 LEU 113 113 113 LEU LEU B . n 
B 2 114 PHE 114 114 114 PHE PHE B . n 
B 2 115 LEU 115 115 115 LEU LEU B . n 
B 2 116 GLY 116 116 116 GLY GLY B . n 
B 2 117 ASP 117 117 117 ASP ASP B . n 
B 2 118 TYR 118 118 118 TYR TYR B . n 
B 2 119 VAL 119 119 119 VAL VAL B . n 
B 2 120 ASP 120 120 120 ASP ASP B . n 
B 2 121 ARG 121 121 121 ARG ARG B . n 
B 2 122 GLY 122 122 122 GLY GLY B . n 
B 2 123 TYR 123 123 123 TYR TYR B . n 
B 2 124 PHE 124 124 124 PHE PHE B . n 
B 2 125 SER 125 125 125 SER SER B . n 
B 2 126 ILE 126 126 126 ILE ILE B . n 
B 2 127 GLU 127 127 127 GLU GLU B . n 
B 2 128 CYS 128 128 128 CYS CYS B . n 
B 2 129 VAL 129 129 129 VAL VAL B . n 
B 2 130 LEU 130 130 130 LEU LEU B . n 
B 2 131 TYR 131 131 131 TYR TYR B . n 
B 2 132 LEU 132 132 132 LEU LEU B . n 
B 2 133 TRP 133 133 133 TRP TRP B . n 
B 2 134 ALA 134 134 134 ALA ALA B . n 
B 2 135 LEU 135 135 135 LEU LEU B . n 
B 2 136 LYS 136 136 136 LYS LYS B . n 
B 2 137 ILE 137 137 137 ILE ILE B . n 
B 2 138 LEU 138 138 138 LEU LEU B . n 
B 2 139 TYR 139 139 139 TYR TYR B . n 
B 2 140 PRO 140 140 140 PRO PRO B . n 
B 2 141 LYS 141 141 141 LYS LYS B . n 
B 2 142 THR 142 142 142 THR THR B . n 
B 2 143 LEU 143 143 143 LEU LEU B . n 
B 2 144 PHE 144 144 144 PHE PHE B . n 
B 2 145 LEU 145 145 145 LEU LEU B . n 
B 2 146 LEU 146 146 146 LEU LEU B . n 
B 2 147 ARG 147 147 147 ARG ARG B . n 
B 2 148 GLY 148 148 148 GLY GLY B . n 
B 2 149 ASN 149 149 149 ASN ASN B . n 
B 2 150 HIS 150 150 150 HIS HIS B . n 
B 2 151 GLU 151 151 151 GLU GLU B . n 
B 2 152 CYS 152 152 152 CYS CYS B . n 
B 2 153 ARG 153 153 153 ARG ARG B . n 
B 2 154 HIS 154 154 154 HIS HIS B . n 
B 2 155 LEU 155 155 155 LEU LEU B . n 
B 2 156 THR 156 156 156 THR THR B . n 
B 2 157 GLU 157 157 157 GLU GLU B . n 
B 2 158 TYR 158 158 158 TYR TYR B . n 
B 2 159 PHE 159 159 159 PHE PHE B . n 
B 2 160 THR 160 160 160 THR THR B . n 
B 2 161 PHE 161 161 161 PHE PHE B . n 
B 2 162 LYS 162 162 162 LYS LYS B . n 
B 2 163 GLN 163 163 163 GLN GLN B . n 
B 2 164 GLU 164 164 164 GLU GLU B . n 
B 2 165 CYS 165 165 165 CYS CYS B . n 
B 2 166 LYS 166 166 166 LYS LYS B . n 
B 2 167 ILE 167 167 167 ILE ILE B . n 
B 2 168 LYS 168 168 168 LYS LYS B . n 
B 2 169 TYR 169 169 169 TYR TYR B . n 
B 2 170 SER 170 170 170 SER SER B . n 
B 2 171 GLU 171 171 171 GLU GLU B . n 
B 2 172 ARG 172 172 172 ARG ARG B . n 
B 2 173 VAL 173 173 173 VAL VAL B . n 
B 2 174 TYR 174 174 174 TYR TYR B . n 
B 2 175 ASP 175 175 175 ASP ASP B . n 
B 2 176 ALA 176 176 176 ALA ALA B . n 
B 2 177 CYS 177 177 177 CYS CYS B . n 
B 2 178 MET 178 178 178 MET MET B . n 
B 2 179 ASP 179 179 179 ASP ASP B . n 
B 2 180 ALA 180 180 180 ALA ALA B . n 
B 2 181 PHE 181 181 181 PHE PHE B . n 
B 2 182 ASP 182 182 182 ASP ASP B . n 
B 2 183 CYS 183 183 183 CYS CYS B . n 
B 2 184 LEU 184 184 184 LEU LEU B . n 
B 2 185 PRO 185 185 185 PRO PRO B . n 
B 2 186 LEU 186 186 186 LEU LEU B . n 
B 2 187 ALA 187 187 187 ALA ALA B . n 
B 2 188 ALA 188 188 188 ALA ALA B . n 
B 2 189 LEU 189 189 189 LEU LEU B . n 
B 2 190 MET 190 190 190 MET MET B . n 
B 2 191 ASN 191 191 191 ASN ASN B . n 
B 2 192 GLN 192 192 192 GLN GLN B . n 
B 2 193 GLN 193 193 193 GLN GLN B . n 
B 2 194 PHE 194 194 194 PHE PHE B . n 
B 2 195 LEU 195 195 195 LEU LEU B . n 
B 2 196 CYS 196 196 196 CYS CYS B . n 
B 2 197 VAL 197 197 197 VAL VAL B . n 
B 2 198 HIS 198 198 198 HIS HIS B . n 
B 2 199 GLY 199 199 199 GLY GLY B . n 
B 2 200 GLY 200 200 200 GLY GLY B . n 
B 2 201 LEU 201 201 201 LEU LEU B . n 
B 2 202 SER 202 202 202 SER SER B . n 
B 2 203 PRO 203 203 203 PRO PRO B . n 
B 2 204 GLU 204 204 204 GLU GLU B . n 
B 2 205 ILE 205 205 205 ILE ILE B . n 
B 2 206 ASN 206 206 206 ASN ASN B . n 
B 2 207 THR 207 207 207 THR THR B . n 
B 2 208 LEU 208 208 208 LEU LEU B . n 
B 2 209 ASP 209 209 209 ASP ASP B . n 
B 2 210 ASP 210 210 210 ASP ASP B . n 
B 2 211 ILE 211 211 211 ILE ILE B . n 
B 2 212 ARG 212 212 212 ARG ARG B . n 
B 2 213 LYS 213 213 213 LYS LYS B . n 
B 2 214 LEU 214 214 214 LEU LEU B . n 
B 2 215 ASP 215 215 215 ASP ASP B . n 
B 2 216 ARG 216 216 216 ARG ARG B . n 
B 2 217 PHE 217 217 217 PHE PHE B . n 
B 2 218 LYS 218 218 218 LYS LYS B . n 
B 2 219 GLU 219 219 219 GLU GLU B . n 
B 2 220 PRO 220 220 220 PRO PRO B . n 
B 2 221 PRO 221 221 221 PRO PRO B . n 
B 2 222 ALA 222 222 222 ALA ALA B . n 
B 2 223 TYR 223 223 223 TYR TYR B . n 
B 2 224 GLY 224 224 224 GLY GLY B . n 
B 2 225 PRO 225 225 225 PRO PRO B . n 
B 2 226 MET 226 226 226 MET MET B . n 
B 2 227 CYS 227 227 227 CYS CYS B . n 
B 2 228 ASP 228 228 228 ASP ASP B . n 
B 2 229 ILE 229 229 229 ILE ILE B . n 
B 2 230 LEU 230 230 230 LEU LEU B . n 
B 2 231 TRP 231 231 231 TRP TRP B . n 
B 2 232 SER 232 232 232 SER SER B . n 
B 2 233 ASP 233 233 233 ASP ASP B . n 
B 2 234 PRO 234 234 234 PRO PRO B . n 
B 2 235 LEU 235 235 235 LEU LEU B . n 
B 2 236 GLU 236 236 236 GLU GLU B . n 
B 2 237 ASP 237 237 237 ASP ASP B . n 
B 2 238 PHE 238 238 238 PHE PHE B . n 
B 2 239 GLY 239 239 239 GLY GLY B . n 
B 2 240 ASN 240 240 240 ASN ASN B . n 
B 2 241 GLU 241 241 241 GLU GLU B . n 
B 2 242 LYS 242 242 242 LYS LYS B . n 
B 2 243 THR 243 243 ?   ?   ?   B . n 
B 2 244 GLN 244 244 ?   ?   ?   B . n 
B 2 245 GLU 245 245 ?   ?   ?   B . n 
B 2 246 HIS 246 246 246 HIS HIS B . n 
B 2 247 PHE 247 247 247 PHE PHE B . n 
B 2 248 THR 248 248 248 THR THR B . n 
B 2 249 HIS 249 249 249 HIS HIS B . n 
B 2 250 ASN 250 250 250 ASN ASN B . n 
B 2 251 THR 251 251 251 THR THR B . n 
B 2 252 VAL 252 252 252 VAL VAL B . n 
B 2 253 ARG 253 253 253 ARG ARG B . n 
B 2 254 GLY 254 254 254 GLY GLY B . n 
B 2 255 CYS 255 255 255 CYS CYS B . n 
B 2 256 SER 256 256 256 SER SER B . n 
B 2 257 TYR 257 257 257 TYR TYR B . n 
B 2 258 PHE 258 258 258 PHE PHE B . n 
B 2 259 TYR 259 259 259 TYR TYR B . n 
B 2 260 SER 260 260 260 SER SER B . n 
B 2 261 TYR 261 261 261 TYR TYR B . n 
B 2 262 PRO 262 262 262 PRO PRO B . n 
B 2 263 ALA 263 263 263 ALA ALA B . n 
B 2 264 VAL 264 264 264 VAL VAL B . n 
B 2 265 CYS 265 265 265 CYS CYS B . n 
B 2 266 ASP 266 266 266 ASP ASP B . n 
B 2 267 PHE 267 267 267 PHE PHE B . n 
B 2 268 LEU 268 268 268 LEU LEU B . n 
B 2 269 GLN 269 269 269 GLN GLN B . n 
B 2 270 HIS 270 270 270 HIS HIS B . n 
B 2 271 ASN 271 271 271 ASN ASN B . n 
B 2 272 ASN 272 272 272 ASN ASN B . n 
B 2 273 LEU 273 273 273 LEU LEU B . n 
B 2 274 LEU 274 274 274 LEU LEU B . n 
B 2 275 SER 275 275 275 SER SER B . n 
B 2 276 ILE 276 276 276 ILE ILE B . n 
B 2 277 LEU 277 277 277 LEU LEU B . n 
B 2 278 ARG 278 278 278 ARG ARG B . n 
B 2 279 ALA 279 279 279 ALA ALA B . n 
B 2 280 HIS 280 280 280 HIS HIS B . n 
B 2 281 GLU 281 281 281 GLU GLU B . n 
B 2 282 ALA 282 282 282 ALA ALA B . n 
B 2 283 GLN 283 283 283 GLN GLN B . n 
B 2 284 ASP 284 284 284 ASP ASP B . n 
B 2 285 ALA 285 285 285 ALA ALA B . n 
B 2 286 GLY 286 286 286 GLY GLY B . n 
B 2 287 TYR 287 287 287 TYR TYR B . n 
B 2 288 ARG 288 288 288 ARG ARG B . n 
B 2 289 MET 289 289 289 MET MET B . n 
B 2 290 TYR 290 290 290 TYR TYR B . n 
B 2 291 ARG 291 291 291 ARG ARG B . n 
B 2 292 LYS 292 292 292 LYS LYS B . n 
B 2 293 SER 293 293 293 SER SER B . n 
B 2 294 GLN 294 294 294 GLN GLN B . n 
B 2 295 THR 295 295 295 THR THR B . n 
B 2 296 THR 296 296 296 THR THR B . n 
B 2 297 GLY 297 297 297 GLY GLY B . n 
B 2 298 PHE 298 298 298 PHE PHE B . n 
B 2 299 PRO 299 299 299 PRO PRO B . n 
B 2 300 SER 300 300 300 SER SER B . n 
B 2 301 LEU 301 301 301 LEU LEU B . n 
B 2 302 ILE 302 302 302 ILE ILE B . n 
B 2 303 THR 303 303 303 THR THR B . n 
B 2 304 ILE 304 304 304 ILE ILE B . n 
B 2 305 PHE 305 305 305 PHE PHE B . n 
B 2 306 SER 306 306 306 SER SER B . n 
B 2 307 ALA 307 307 307 ALA ALA B . n 
B 2 308 PRO 308 308 308 PRO PRO B . n 
B 2 309 ASN 309 309 309 ASN ASN B . n 
B 2 310 TYR 310 310 310 TYR TYR B . n 
B 2 311 LEU 311 311 311 LEU LEU B . n 
B 2 312 ASP 312 312 312 ASP ASP B . n 
B 2 313 VAL 313 313 313 VAL VAL B . n 
B 2 314 TYR 314 314 314 TYR TYR B . n 
B 2 315 ASN 315 315 315 ASN ASN B . n 
B 2 316 ASN 316 316 316 ASN ASN B . n 
B 2 317 LYS 317 317 317 LYS LYS B . n 
B 2 318 ALA 318 318 318 ALA ALA B . n 
B 2 319 ALA 319 319 319 ALA ALA B . n 
B 2 320 VAL 320 320 320 VAL VAL B . n 
B 2 321 LEU 321 321 321 LEU LEU B . n 
B 2 322 LYS 322 322 322 LYS LYS B . n 
B 2 323 TYR 323 323 323 TYR TYR B . n 
B 2 324 GLU 324 324 324 GLU GLU B . n 
B 2 325 ASN 325 325 325 ASN ASN B . n 
B 2 326 ASN 326 326 326 ASN ASN B . n 
B 2 327 VAL 327 327 327 VAL VAL B . n 
B 2 328 MET 328 328 328 MET MET B . n 
B 2 329 ASN 329 329 329 ASN ASN B . n 
B 2 330 ILE 330 330 330 ILE ILE B . n 
B 2 331 ARG 331 331 331 ARG ARG B . n 
B 2 332 GLN 332 332 332 GLN GLN B . n 
B 2 333 PHE 333 333 333 PHE PHE B . n 
B 2 334 ASN 334 334 334 ASN ASN B . n 
B 2 335 CYS 335 335 335 CYS CYS B . n 
B 2 336 SER 336 336 336 SER SER B . n 
B 2 337 PRO 337 337 337 PRO PRO B . n 
B 2 338 HIS 338 338 338 HIS HIS B . n 
B 2 339 PRO 339 339 339 PRO PRO B . n 
B 2 340 TYR 340 340 340 TYR TYR B . n 
B 2 341 TRP 341 341 341 TRP TRP B . n 
B 2 342 LEU 342 342 342 LEU LEU B . n 
B 2 343 PRO 343 343 343 PRO PRO B . n 
B 2 344 ASN 344 344 344 ASN ASN B . n 
B 2 345 PHE 345 345 345 PHE PHE B . n 
B 2 346 MET 346 346 346 MET MET B . n 
B 2 347 ASP 347 347 347 ASP ASP B . n 
B 2 348 VAL 348 348 348 VAL VAL B . n 
B 2 349 PHE 349 349 349 PHE PHE B . n 
B 2 350 THR 350 350 350 THR THR B . n 
B 2 351 TRP 351 351 351 TRP TRP B . n 
B 2 352 SER 352 352 352 SER SER B . n 
B 2 353 LEU 353 353 353 LEU LEU B . n 
B 2 354 PRO 354 354 354 PRO PRO B . n 
B 2 355 PHE 355 355 355 PHE PHE B . n 
B 2 356 VAL 356 356 356 VAL VAL B . n 
B 2 357 GLY 357 357 357 GLY GLY B . n 
B 2 358 GLU 358 358 358 GLU GLU B . n 
B 2 359 LYS 359 359 359 LYS LYS B . n 
B 2 360 VAL 360 360 360 VAL VAL B . n 
B 2 361 THR 361 361 361 THR THR B . n 
B 2 362 GLU 362 362 362 GLU GLU B . n 
B 2 363 MET 363 363 363 MET MET B . n 
B 2 364 LEU 364 364 364 LEU LEU B . n 
B 2 365 VAL 365 365 365 VAL VAL B . n 
B 2 366 ASN 366 366 366 ASN ASN B . n 
B 2 367 VAL 367 367 367 VAL VAL B . n 
B 2 368 LEU 368 368 368 LEU LEU B . n 
B 2 369 ASN 369 369 369 ASN ASN B . n 
B 2 370 ILE 370 370 ?   ?   ?   B . n 
C 3 1   MET 1   0   ?   ?   ?   C . n 
C 3 2   GLY 2   1   1   GLY GLY C . n 
C 3 3   VAL 3   2   2   VAL VAL C . n 
C 3 4   GLN 4   3   3   GLN GLN C . n 
C 3 5   VAL 5   4   4   VAL VAL C . n 
C 3 6   GLU 6   5   5   GLU GLU C . n 
C 3 7   THR 7   6   6   THR THR C . n 
C 3 8   ILE 8   7   7   ILE ILE C . n 
C 3 9   SER 9   8   8   SER SER C . n 
C 3 10  PRO 10  9   9   PRO PRO C . n 
C 3 11  GLY 11  10  10  GLY GLY C . n 
C 3 12  ASP 12  11  11  ASP ASP C . n 
C 3 13  GLY 13  12  12  GLY GLY C . n 
C 3 14  ARG 14  13  13  ARG ARG C . n 
C 3 15  THR 15  14  14  THR THR C . n 
C 3 16  PHE 16  15  15  PHE PHE C . n 
C 3 17  PRO 17  16  16  PRO PRO C . n 
C 3 18  LYS 18  17  17  LYS LYS C . n 
C 3 19  ARG 19  18  18  ARG ARG C . n 
C 3 20  GLY 20  19  19  GLY GLY C . n 
C 3 21  GLN 21  20  20  GLN GLN C . n 
C 3 22  THR 22  21  21  THR THR C . n 
C 3 23  CYS 23  22  22  CYS CYS C . n 
C 3 24  VAL 24  23  23  VAL VAL C . n 
C 3 25  VAL 25  24  24  VAL VAL C . n 
C 3 26  HIS 26  25  25  HIS HIS C . n 
C 3 27  TYR 27  26  26  TYR TYR C . n 
C 3 28  THR 28  27  27  THR THR C . n 
C 3 29  GLY 29  28  28  GLY GLY C . n 
C 3 30  MET 30  29  29  MET MET C . n 
C 3 31  LEU 31  30  30  LEU LEU C . n 
C 3 32  GLU 32  31  31  GLU GLU C . n 
C 3 33  ASP 33  32  32  ASP ASP C . n 
C 3 34  GLY 34  33  33  GLY GLY C . n 
C 3 35  LYS 35  34  34  LYS LYS C . n 
C 3 36  LYS 36  35  35  LYS LYS C . n 
C 3 37  PHE 37  36  36  PHE PHE C . n 
C 3 38  ASP 38  37  37  ASP ASP C . n 
C 3 39  SER 39  38  38  SER SER C . n 
C 3 40  SER 40  39  39  SER SER C . n 
C 3 41  ARG 41  40  40  ARG ARG C . n 
C 3 42  ASP 42  41  41  ASP ASP C . n 
C 3 43  ARG 43  42  42  ARG ARG C . n 
C 3 44  ASN 44  43  43  ASN ASN C . n 
C 3 45  LYS 45  44  44  LYS LYS C . n 
C 3 46  PRO 46  45  45  PRO PRO C . n 
C 3 47  PHE 47  46  46  PHE PHE C . n 
C 3 48  LYS 48  47  47  LYS LYS C . n 
C 3 49  PHE 49  48  48  PHE PHE C . n 
C 3 50  MET 50  49  49  MET MET C . n 
C 3 51  LEU 51  50  50  LEU LEU C . n 
C 3 52  GLY 52  51  51  GLY GLY C . n 
C 3 53  LYS 53  52  52  LYS LYS C . n 
C 3 54  GLN 54  53  53  GLN GLN C . n 
C 3 55  GLU 55  54  54  GLU GLU C . n 
C 3 56  VAL 56  55  55  VAL VAL C . n 
C 3 57  ILE 57  56  56  ILE ILE C . n 
C 3 58  ARG 58  57  57  ARG ARG C . n 
C 3 59  GLY 59  58  58  GLY GLY C . n 
C 3 60  TRP 60  59  59  TRP TRP C . n 
C 3 61  GLU 61  60  60  GLU GLU C . n 
C 3 62  GLU 62  61  61  GLU GLU C . n 
C 3 63  GLY 63  62  62  GLY GLY C . n 
C 3 64  VAL 64  63  63  VAL VAL C . n 
C 3 65  ALA 65  64  64  ALA ALA C . n 
C 3 66  GLN 66  65  65  GLN GLN C . n 
C 3 67  MET 67  66  66  MET MET C . n 
C 3 68  SER 68  67  67  SER SER C . n 
C 3 69  VAL 69  68  68  VAL VAL C . n 
C 3 70  GLY 70  69  69  GLY GLY C . n 
C 3 71  GLN 71  70  70  GLN GLN C . n 
C 3 72  ARG 72  71  71  ARG ARG C . n 
C 3 73  ALA 73  72  72  ALA ALA C . n 
C 3 74  LYS 74  73  73  LYS LYS C . n 
C 3 75  LEU 75  74  74  LEU LEU C . n 
C 3 76  THR 76  75  75  THR THR C . n 
C 3 77  ILE 77  76  76  ILE ILE C . n 
C 3 78  SER 78  77  77  SER SER C . n 
C 3 79  PRO 79  78  78  PRO PRO C . n 
C 3 80  ASP 80  79  79  ASP ASP C . n 
C 3 81  TYR 81  80  80  TYR TYR C . n 
C 3 82  ALA 82  81  81  ALA ALA C . n 
C 3 83  TYR 83  82  82  TYR TYR C . n 
C 3 84  GLY 84  83  83  GLY GLY C . n 
C 3 85  ALA 85  84  84  ALA ALA C . n 
C 3 86  THR 86  85  85  THR THR C . n 
C 3 87  GLY 87  86  86  GLY GLY C . n 
C 3 88  HIS 88  87  87  HIS HIS C . n 
C 3 89  PRO 89  88  88  PRO PRO C . n 
C 3 90  GLY 90  89  89  GLY GLY C . n 
C 3 91  ILE 91  90  90  ILE ILE C . n 
C 3 92  ILE 92  91  91  ILE ILE C . n 
C 3 93  PRO 93  92  92  PRO PRO C . n 
C 3 94  PRO 94  93  93  PRO PRO C . n 
C 3 95  HIS 95  94  94  HIS HIS C . n 
C 3 96  ALA 96  95  95  ALA ALA C . n 
C 3 97  THR 97  96  96  THR THR C . n 
C 3 98  LEU 98  97  97  LEU LEU C . n 
C 3 99  VAL 99  98  98  VAL VAL C . n 
C 3 100 PHE 100 99  99  PHE PHE C . n 
C 3 101 ASP 101 100 100 ASP ASP C . n 
C 3 102 VAL 102 101 101 VAL VAL C . n 
C 3 103 GLU 103 102 102 GLU GLU C . n 
C 3 104 LEU 104 103 103 LEU LEU C . n 
C 3 105 LEU 105 104 104 LEU LEU C . n 
C 3 106 LYS 106 105 105 LYS LYS C . n 
C 3 107 LEU 107 106 106 LEU LEU C . n 
C 3 108 GLU 108 107 107 GLU GLU C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        FK5 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   FK5 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4 E5E 1 501 501 E5E NOR A . 
E 5 FK5 1 201 108 FK5 FK5 C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A TRP 32  ? CG  ? A TRP 4   CG  
2   1 Y 1 A TRP 32  ? CD1 ? A TRP 4   CD1 
3   1 Y 1 A TRP 32  ? CD2 ? A TRP 4   CD2 
4   1 Y 1 A TRP 32  ? NE1 ? A TRP 4   NE1 
5   1 Y 1 A TRP 32  ? CE2 ? A TRP 4   CE2 
6   1 Y 1 A TRP 32  ? CE3 ? A TRP 4   CE3 
7   1 Y 1 A TRP 32  ? CZ2 ? A TRP 4   CZ2 
8   1 Y 1 A TRP 32  ? CZ3 ? A TRP 4   CZ3 
9   1 Y 1 A TRP 32  ? CH2 ? A TRP 4   CH2 
10  1 Y 1 A VAL 34  ? CG1 ? A VAL 6   CG1 
11  1 Y 1 A VAL 34  ? CG2 ? A VAL 6   CG2 
12  1 Y 1 A ILE 38  ? CG1 ? A ILE 10  CG1 
13  1 Y 1 A ILE 38  ? CG2 ? A ILE 10  CG2 
14  1 Y 1 A ILE 38  ? CD1 ? A ILE 10  CD1 
15  1 Y 1 A LEU 42  ? CG  ? A LEU 14  CG  
16  1 Y 1 A LEU 42  ? CD1 ? A LEU 14  CD1 
17  1 Y 1 A LEU 42  ? CD2 ? A LEU 14  CD2 
18  1 Y 1 A LEU 45  ? CG  ? A LEU 17  CG  
19  1 Y 1 A LEU 45  ? CD1 ? A LEU 17  CD1 
20  1 Y 1 A LEU 45  ? CD2 ? A LEU 17  CD2 
21  1 Y 1 A PHE 49  ? CG  ? A PHE 21  CG  
22  1 Y 1 A PHE 49  ? CD1 ? A PHE 21  CD1 
23  1 Y 1 A PHE 49  ? CD2 ? A PHE 21  CD2 
24  1 Y 1 A PHE 49  ? CE1 ? A PHE 21  CE1 
25  1 Y 1 A PHE 49  ? CE2 ? A PHE 21  CE2 
26  1 Y 1 A PHE 49  ? CZ  ? A PHE 21  CZ  
27  1 Y 1 A VAL 52  ? CG1 ? A VAL 24  CG1 
28  1 Y 1 A VAL 52  ? CG2 ? A VAL 24  CG2 
29  1 Y 1 A THR 56  ? OG1 ? A THR 28  OG1 
30  1 Y 1 A THR 56  ? CG2 ? A THR 28  CG2 
31  1 Y 1 A HIS 172 ? CG  ? A HIS 144 CG  
32  1 Y 1 A HIS 172 ? ND1 ? A HIS 144 ND1 
33  1 Y 1 A HIS 172 ? CD2 ? A HIS 144 CD2 
34  1 Y 1 A HIS 172 ? CE1 ? A HIS 144 CE1 
35  1 Y 1 A HIS 172 ? NE2 ? A HIS 144 NE2 
36  1 Y 1 A GLN 179 ? CG  ? A GLN 151 CG  
37  1 Y 1 A GLN 179 ? CD  ? A GLN 151 CD  
38  1 Y 1 A GLN 179 ? OE1 ? A GLN 151 OE1 
39  1 Y 1 A GLN 179 ? NE2 ? A GLN 151 NE2 
40  1 Y 1 A GLU 180 ? CG  ? A GLU 152 CG  
41  1 Y 1 A GLU 180 ? CD  ? A GLU 152 CD  
42  1 Y 1 A GLU 180 ? OE1 ? A GLU 152 OE1 
43  1 Y 1 A GLU 180 ? OE2 ? A GLU 152 OE2 
44  1 Y 1 A ASN 183 ? CG  ? A ASN 155 CG  
45  1 Y 1 A ASN 183 ? OD1 ? A ASN 155 OD1 
46  1 Y 1 A ASN 183 ? ND2 ? A ASN 155 ND2 
47  1 Y 1 A TYR 185 ? CG  ? A TYR 157 CG  
48  1 Y 1 A TYR 185 ? CD1 ? A TYR 157 CD1 
49  1 Y 1 A TYR 185 ? CD2 ? A TYR 157 CD2 
50  1 Y 1 A TYR 185 ? CE1 ? A TYR 157 CE1 
51  1 Y 1 A TYR 185 ? CE2 ? A TYR 157 CE2 
52  1 Y 1 A TYR 185 ? CZ  ? A TYR 157 CZ  
53  1 Y 1 A TYR 185 ? OH  ? A TYR 157 OH  
54  1 Y 1 A GLU 187 ? CG  ? A GLU 159 CG  
55  1 Y 1 A GLU 187 ? CD  ? A GLU 159 CD  
56  1 Y 1 A GLU 187 ? OE1 ? A GLU 159 OE1 
57  1 Y 1 A GLU 187 ? OE2 ? A GLU 159 OE2 
58  1 Y 1 A GLU 188 ? CG  ? A GLU 160 CG  
59  1 Y 1 A GLU 188 ? CD  ? A GLU 160 CD  
60  1 Y 1 A GLU 188 ? OE1 ? A GLU 160 OE1 
61  1 Y 1 A GLU 188 ? OE2 ? A GLU 160 OE2 
62  1 Y 1 A ASP 192 ? CG  ? A ASP 164 CG  
63  1 Y 1 A ASP 192 ? OD1 ? A ASP 164 OD1 
64  1 Y 1 A ASP 192 ? OD2 ? A ASP 164 OD2 
65  1 Y 1 A LYS 227 ? CG  ? A LYS 199 CG  
66  1 Y 1 A LYS 227 ? CD  ? A LYS 199 CD  
67  1 Y 1 A LYS 227 ? CE  ? A LYS 199 CE  
68  1 Y 1 A LYS 227 ? NZ  ? A LYS 199 NZ  
69  1 Y 1 A LYS 288 ? CG  ? A LYS 260 CG  
70  1 Y 1 A LYS 288 ? CD  ? A LYS 260 CD  
71  1 Y 1 A LYS 288 ? CE  ? A LYS 260 CE  
72  1 Y 1 A LYS 288 ? NZ  ? A LYS 260 NZ  
73  1 Y 1 A LYS 300 ? CG  ? A LYS 272 CG  
74  1 Y 1 A LYS 300 ? CD  ? A LYS 272 CD  
75  1 Y 1 A LYS 300 ? CE  ? A LYS 272 CE  
76  1 Y 1 A LYS 300 ? NZ  ? A LYS 272 NZ  
77  1 Y 1 A VAL 420 ? CG1 ? A VAL 392 CG1 
78  1 Y 1 A VAL 420 ? CG2 ? A VAL 392 CG2 
79  1 Y 1 A GLN 422 ? CG  ? A GLN 394 CG  
80  1 Y 1 A GLN 422 ? CD  ? A GLN 394 CD  
81  1 Y 1 A GLN 422 ? OE1 ? A GLN 394 OE1 
82  1 Y 1 A GLN 422 ? NE2 ? A GLN 394 NE2 
83  1 Y 1 A ASP 423 ? CG  ? A ASP 395 CG  
84  1 Y 1 A ASP 423 ? OD1 ? A ASP 395 OD1 
85  1 Y 1 A ASP 423 ? OD2 ? A ASP 395 OD2 
86  1 Y 1 A ASN 424 ? CG  ? A ASN 396 CG  
87  1 Y 1 A ASN 424 ? OD1 ? A ASN 396 OD1 
88  1 Y 1 A ASN 424 ? ND2 ? A ASN 396 ND2 
89  1 Y 1 A LEU 425 ? CG  ? A LEU 397 CG  
90  1 Y 1 A LEU 425 ? CD1 ? A LEU 397 CD1 
91  1 Y 1 A LEU 425 ? CD2 ? A LEU 397 CD2 
92  1 Y 1 A ILE 426 ? CG1 ? A ILE 398 CG1 
93  1 Y 1 A ILE 426 ? CG2 ? A ILE 398 CG2 
94  1 Y 1 A ILE 426 ? CD1 ? A ILE 398 CD1 
95  1 Y 1 A ARG 427 ? CG  ? A ARG 399 CG  
96  1 Y 1 A ARG 427 ? CD  ? A ARG 399 CD  
97  1 Y 1 A ARG 427 ? NE  ? A ARG 399 NE  
98  1 Y 1 A ARG 427 ? CZ  ? A ARG 399 CZ  
99  1 Y 1 A ARG 427 ? NH1 ? A ARG 399 NH1 
100 1 Y 1 A ARG 427 ? NH2 ? A ARG 399 NH2 
101 1 Y 1 A LYS 428 ? CG  ? A LYS 400 CG  
102 1 Y 1 A LYS 428 ? CD  ? A LYS 400 CD  
103 1 Y 1 A LYS 428 ? CE  ? A LYS 400 CE  
104 1 Y 1 A LYS 428 ? NZ  ? A LYS 400 NZ  
105 1 Y 1 A GLU 429 ? CG  ? A GLU 401 CG  
106 1 Y 1 A GLU 429 ? CD  ? A GLU 401 CD  
107 1 Y 1 A GLU 429 ? OE1 ? A GLU 401 OE1 
108 1 Y 1 A GLU 429 ? OE2 ? A GLU 401 OE2 
109 1 Y 1 B LYS 31  ? CG  ? B LYS 31  CG  
110 1 Y 1 B LYS 31  ? CD  ? B LYS 31  CD  
111 1 Y 1 B LYS 31  ? CE  ? B LYS 31  CE  
112 1 Y 1 B LYS 31  ? NZ  ? B LYS 31  NZ  
113 1 Y 1 B ARG 41  ? CG  ? B ARG 41  CG  
114 1 Y 1 B ARG 41  ? CD  ? B ARG 41  CD  
115 1 Y 1 B ARG 41  ? NE  ? B ARG 41  NE  
116 1 Y 1 B ARG 41  ? CZ  ? B ARG 41  CZ  
117 1 Y 1 B ARG 41  ? NH1 ? B ARG 41  NH1 
118 1 Y 1 B ARG 41  ? NH2 ? B ARG 41  NH2 
119 1 Y 1 B GLU 56  ? CG  ? B GLU 56  CG  
120 1 Y 1 B GLU 56  ? CD  ? B GLU 56  CD  
121 1 Y 1 B GLU 56  ? OE1 ? B GLU 56  OE1 
122 1 Y 1 B GLU 56  ? OE2 ? B GLU 56  OE2 
123 1 Y 1 B GLU 157 ? CG  ? B GLU 157 CG  
124 1 Y 1 B GLU 157 ? CD  ? B GLU 157 CD  
125 1 Y 1 B GLU 157 ? OE1 ? B GLU 157 OE1 
126 1 Y 1 B GLU 157 ? OE2 ? B GLU 157 OE2 
127 1 Y 1 B GLN 192 ? CG  ? B GLN 192 CG  
128 1 Y 1 B GLN 192 ? CD  ? B GLN 192 CD  
129 1 Y 1 B GLN 192 ? OE1 ? B GLN 192 OE1 
130 1 Y 1 B GLN 192 ? NE2 ? B GLN 192 NE2 
131 1 Y 1 B ASP 209 ? CG  ? B ASP 209 CG  
132 1 Y 1 B ASP 209 ? OD1 ? B ASP 209 OD1 
133 1 Y 1 B ASP 209 ? OD2 ? B ASP 209 OD2 
134 1 Y 1 B ASP 210 ? CG  ? B ASP 210 CG  
135 1 Y 1 B ASP 210 ? OD1 ? B ASP 210 OD1 
136 1 Y 1 B ASP 210 ? OD2 ? B ASP 210 OD2 
137 1 Y 1 B ARG 216 ? CG  ? B ARG 216 CG  
138 1 Y 1 B ARG 216 ? CD  ? B ARG 216 CD  
139 1 Y 1 B ARG 216 ? NE  ? B ARG 216 NE  
140 1 Y 1 B ARG 216 ? CZ  ? B ARG 216 CZ  
141 1 Y 1 B ARG 216 ? NH1 ? B ARG 216 NH1 
142 1 Y 1 B ARG 216 ? NH2 ? B ARG 216 NH2 
143 1 Y 1 B ASP 228 ? CG  ? B ASP 228 CG  
144 1 Y 1 B ASP 228 ? OD1 ? B ASP 228 OD1 
145 1 Y 1 B ASP 228 ? OD2 ? B ASP 228 OD2 
146 1 Y 1 B LYS 242 ? CG  ? B LYS 242 CG  
147 1 Y 1 B LYS 242 ? CD  ? B LYS 242 CD  
148 1 Y 1 B LYS 242 ? CE  ? B LYS 242 CE  
149 1 Y 1 B LYS 242 ? NZ  ? B LYS 242 NZ  
150 1 Y 1 B PHE 247 ? CG  ? B PHE 247 CG  
151 1 Y 1 B PHE 247 ? CD1 ? B PHE 247 CD1 
152 1 Y 1 B PHE 247 ? CD2 ? B PHE 247 CD2 
153 1 Y 1 B PHE 247 ? CE1 ? B PHE 247 CE1 
154 1 Y 1 B PHE 247 ? CE2 ? B PHE 247 CE2 
155 1 Y 1 B PHE 247 ? CZ  ? B PHE 247 CZ  
156 1 Y 1 B GLU 324 ? CG  ? B GLU 324 CG  
157 1 Y 1 B GLU 324 ? CD  ? B GLU 324 CD  
158 1 Y 1 B GLU 324 ? OE1 ? B GLU 324 OE1 
159 1 Y 1 B GLU 324 ? OE2 ? B GLU 324 OE2 
160 1 Y 1 B ASN 334 ? CG  ? B ASN 334 CG  
161 1 Y 1 B ASN 334 ? OD1 ? B ASN 334 OD1 
162 1 Y 1 B ASN 334 ? ND2 ? B ASN 334 ND2 
163 1 Y 1 C ARG 13  ? CG  ? C ARG 14  CG  
164 1 Y 1 C ARG 13  ? CD  ? C ARG 14  CD  
165 1 Y 1 C ARG 13  ? NE  ? C ARG 14  NE  
166 1 Y 1 C ARG 13  ? CZ  ? C ARG 14  CZ  
167 1 Y 1 C ARG 13  ? NH1 ? C ARG 14  NH1 
168 1 Y 1 C ARG 13  ? NH2 ? C ARG 14  NH2 
169 1 Y 1 C MET 49  ? CG  ? C MET 50  CG  
170 1 Y 1 C MET 49  ? SD  ? C MET 50  SD  
171 1 Y 1 C MET 49  ? CE  ? C MET 50  CE  
172 1 Y 1 C ARG 57  ? CG  ? C ARG 58  CG  
173 1 Y 1 C ARG 57  ? CD  ? C ARG 58  CD  
174 1 Y 1 C ARG 57  ? NE  ? C ARG 58  NE  
175 1 Y 1 C ARG 57  ? CZ  ? C ARG 58  CZ  
176 1 Y 1 C ARG 57  ? NH1 ? C ARG 58  NH1 
177 1 Y 1 C ARG 57  ? NH2 ? C ARG 58  NH2 
178 1 Y 1 C GLU 60  ? CG  ? C GLU 61  CG  
179 1 Y 1 C GLU 60  ? CD  ? C GLU 61  CD  
180 1 Y 1 C GLU 60  ? OE1 ? C GLU 61  OE1 
181 1 Y 1 C GLU 60  ? OE2 ? C GLU 61  OE2 
182 1 Y 1 C GLU 102 ? CG  ? C GLU 103 CG  
183 1 Y 1 C GLU 102 ? CD  ? C GLU 103 CD  
184 1 Y 1 C GLU 102 ? OE1 ? C GLU 103 OE1 
185 1 Y 1 C GLU 102 ? OE2 ? C GLU 103 OE2 
186 1 Y 1 C GLU 107 ? O   ? C GLU 108 O   
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CHU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CHU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CHU 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CHU 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.005  ? 7262 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.698  ? 9855 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 12.871 ? 1000 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.044  ? 1112 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1246 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9CHU 
_struct.title                        
'Cryo-EM structure of calcineurin fused beta2 adrenergic receptor in norepinephrine bound inactive state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CHU 
_struct_keywords.text            
'GPCR, beta2AR, calcineurin, inactive state, MEMBRANE PROTEIN, MEMBRANE PROTEIN-HYDROLASE-ISOMERASE complex' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN/HYDROLASE/ISOMERASE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP ADRB2_HUMAN P07550 ? 1 
;DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEF
WTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANE
TCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQL
;
29  
2 UNP CANB1_HUMAN P63098 ? 1 
;DADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFA
FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
;
16  
3 UNP ADRB2_HUMAN P07550 ? 1 KFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAF 263 
4 UNP PP2BA_MOUSE P63328 ? 2 
;SEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDI
DAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT
FKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGN
EKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAV
LKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNI
;
2   
5 UNP FKB1A_HUMAN P62942 ? 3 
;MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPD
YAYGATGHPGIIPPHATLVFDVELLKLE
;
1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CHU A 1   ? 202 ? P07550 29  ? 230 ? 29  230 
2 2 9CHU A 203 ? 357 ? P63098 16  ? 170 ? 231 385 
3 3 9CHU A 358 ? 431 ? P07550 263 ? 336 ? 386 459 
4 4 9CHU B 1   ? 370 ? P63328 2   ? 371 ? 1   370 
5 5 9CHU C 1   ? 108 ? P62942 1   ? 108 ? 0   107 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9CHU 
_struct_ref_seq_dif.mon_id                       GLU 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      159 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   P07550 
_struct_ref_seq_dif.db_mon_id                    ASN 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          187 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            187 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 TRP A 4   ? PHE A 33  ? TRP A 32  PHE A 61  1 ? 30 
HELX_P HELX_P2  AA2 THR A 38  ? LYS A 69  ? THR A 66  LYS A 97  1 ? 32 
HELX_P HELX_P3  AA3 GLY A 74  ? SER A 109 ? GLY A 102 SER A 137 1 ? 36 
HELX_P HELX_P4  AA4 SER A 109 ? LEU A 117 ? SER A 137 LEU A 145 1 ? 9  
HELX_P HELX_P5  AA5 THR A 118 ? MET A 143 ? THR A 146 MET A 171 1 ? 26 
HELX_P HELX_P6  AA6 HIS A 150 ? GLU A 159 ? HIS A 178 GLU A 187 1 ? 10 
HELX_P HELX_P7  AA7 ALA A 170 ? PHE A 180 ? ALA A 198 PHE A 208 1 ? 11 
HELX_P HELX_P8  AA8 TYR A 181 ? LEU A 202 ? TYR A 209 LEU A 230 1 ? 22 
HELX_P HELX_P9  AA9 GLU A 206 ? ASP A 218 ? GLU A 234 ASP A 246 1 ? 13 
HELX_P HELX_P10 AB1 SER A 226 ? MET A 231 ? SER A 254 MET A 259 1 ? 6  
HELX_P HELX_P11 AB2 ASN A 239 ? LEU A 241 ? ASN A 267 LEU A 269 5 ? 3  
HELX_P HELX_P12 AB3 VAL A 242 ? ASP A 250 ? VAL A 270 ASP A 278 1 ? 9  
HELX_P HELX_P13 AB4 ASP A 258 ? SER A 267 ? ASP A 286 SER A 295 1 ? 10 
HELX_P HELX_P14 AB5 ASP A 274 ? ILE A 285 ? ASP A 302 ILE A 313 1 ? 12 
HELX_P HELX_P15 AB6 SER A 295 ? MET A 305 ? SER A 323 MET A 333 1 ? 11 
HELX_P HELX_P16 AB7 LYS A 312 ? ASP A 328 ? LYS A 340 ASP A 356 1 ? 17 
HELX_P HELX_P17 AB8 SER A 336 ? VAL A 344 ? SER A 364 VAL A 372 1 ? 9  
HELX_P HELX_P18 AB9 LEU A 367 ? ILE A 393 ? LEU A 395 ILE A 421 1 ? 27 
HELX_P HELX_P19 AC1 VAL A 402 ? ASN A 413 ? VAL A 430 ASN A 441 1 ? 12 
HELX_P HELX_P20 AC2 GLY A 415 ? SER A 424 ? GLY A 443 SER A 452 1 ? 10 
HELX_P HELX_P21 AC3 SER A 424 ? PHE A 431 ? SER A 452 PHE A 459 1 ? 8  
HELX_P HELX_P22 AC4 VAL B 42  ? MET B 50  ? VAL B 42  MET B 50  1 ? 9  
HELX_P HELX_P23 AC5 GLU B 56  ? GLN B 73  ? GLU B 56  GLN B 73  1 ? 18 
HELX_P HELX_P24 AC6 GLN B 93  ? GLY B 104 ? GLN B 93  GLY B 104 1 ? 12 
HELX_P HELX_P25 AC7 PHE B 124 ? TYR B 139 ? PHE B 124 TYR B 139 1 ? 16 
HELX_P HELX_P26 AC8 ARG B 153 ? PHE B 159 ? ARG B 153 PHE B 159 1 ? 7  
HELX_P HELX_P27 AC9 PHE B 161 ? TYR B 169 ? PHE B 161 TYR B 169 1 ? 9  
HELX_P HELX_P28 AD1 SER B 170 ? ASP B 182 ? SER B 170 ASP B 182 1 ? 13 
HELX_P HELX_P29 AD2 THR B 207 ? ARG B 212 ? THR B 207 ARG B 212 5 ? 6  
HELX_P HELX_P30 AD3 MET B 226 ? TRP B 231 ? MET B 226 TRP B 231 1 ? 6  
HELX_P HELX_P31 AD4 SER B 260 ? ASN B 271 ? SER B 260 ASN B 271 1 ? 12 
HELX_P HELX_P32 AD5 ASN B 309 ? VAL B 313 ? ASN B 309 VAL B 313 5 ? 5  
HELX_P HELX_P33 AD6 ASP B 347 ? LEU B 368 ? ASP B 347 LEU B 368 1 ? 22 
HELX_P HELX_P34 AD7 ILE C 57  ? GLU C 62  ? ILE C 56  GLU C 61  1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 78  SG ? ? ? 1_555 A CYS 163 SG ? ? A CYS 106 A CYS 191 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ? ? A CYS 156 SG ? ? ? 1_555 A CYS 162 SG ? ? A CYS 184 A CYS 190 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 78  ? CYS A 163 ? CYS A 106 ? 1_555 CYS A 191 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 156 ? CYS A 162 ? CYS A 184 ? 1_555 CYS A 190 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ASP B 79  ? ILE B 80  ? ASP B 79  ILE B 80  
AA1 2 LEU B 189 ? MET B 190 ? LEU B 189 MET B 190 
AA1 3 PHE B 194 ? CYS B 196 ? PHE B 194 CYS B 196 
AA1 4 SER B 275 ? ARG B 278 ? SER B 275 ARG B 278 
AA1 5 LEU B 301 ? ILE B 304 ? LEU B 301 ILE B 304 
AA1 6 TYR B 287 ? MET B 289 ? TYR B 287 MET B 289 
AA2 1 VAL B 84  ? CYS B 87  ? VAL B 84  CYS B 87  
AA2 2 ARG B 111 ? PHE B 114 ? ARG B 111 PHE B 114 
AA2 3 LEU B 143 ? LEU B 145 ? LEU B 143 LEU B 145 
AA3 1 ALA B 319 ? GLU B 324 ? ALA B 319 GLU B 324 
AA3 2 VAL B 327 ? GLN B 332 ? VAL B 327 GLN B 332 
AA4 1 PHE C 47  ? MET C 50  ? PHE C 46  MET C 49  
AA4 2 THR C 22  ? VAL C 25  ? THR C 21  VAL C 24  
AA4 3 LEU C 104 ? LEU C 107 ? LEU C 103 LEU C 106 
AA5 1 LYS C 36  ? SER C 39  ? LYS C 35  SER C 38  
AA5 2 THR C 28  ? LEU C 31  ? THR C 27  LEU C 30  
AA5 3 LEU C 98  ? PHE C 100 ? LEU C 97  PHE C 99  
AA5 4 LEU C 75  ? ILE C 77  ? LEU C 74  ILE C 76  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE B 80  ? N ILE B 80  O LEU B 189 ? O LEU B 189 
AA1 2 3 N MET B 190 ? N MET B 190 O PHE B 194 ? O PHE B 194 
AA1 3 4 N LEU B 195 ? N LEU B 195 O LEU B 277 ? O LEU B 277 
AA1 4 5 N ARG B 278 ? N ARG B 278 O ILE B 304 ? O ILE B 304 
AA1 5 6 O THR B 303 ? O THR B 303 N ARG B 288 ? N ARG B 288 
AA2 1 2 N CYS B 87  ? N CYS B 87  O LEU B 113 ? O LEU B 113 
AA2 2 3 N TYR B 112 ? N TYR B 112 O PHE B 144 ? O PHE B 144 
AA3 1 2 N VAL B 320 ? N VAL B 320 O ARG B 331 ? O ARG B 331 
AA4 1 2 O PHE C 47  ? O PHE C 46  N VAL C 25  ? N VAL C 24  
AA4 2 3 N VAL C 24  ? N VAL C 23  O LEU C 105 ? O LEU C 104 
AA5 1 2 O ASP C 38  ? O ASP C 37  N GLY C 29  ? N GLY C 28  
AA5 2 3 N MET C 30  ? N MET C 29  O VAL C 99  ? O VAL C 98  
AA5 3 4 O PHE C 100 ? O PHE C 99  N LEU C 75  ? N LEU C 74  
# 
_pdbx_entry_details.entry_id                   9CHU 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OH 
_pdbx_validate_close_contact.auth_asym_id_1   C 
_pdbx_validate_close_contact.auth_comp_id_1   TYR 
_pdbx_validate_close_contact.auth_seq_id_1    82 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O3 
_pdbx_validate_close_contact.auth_asym_id_2   C 
_pdbx_validate_close_contact.auth_comp_id_2   FK5 
_pdbx_validate_close_contact.auth_seq_id_2    201 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.17 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CA 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            SER 
_pdbx_validate_rmsd_bond.auth_seq_id_1             204 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            CB 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            SER 
_pdbx_validate_rmsd_bond.auth_seq_id_2             204 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.424 
_pdbx_validate_rmsd_bond.bond_target_value         1.525 
_pdbx_validate_rmsd_bond.bond_deviation            -0.101 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.015 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             N 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             SER 
_pdbx_validate_rmsd_angle.auth_seq_id_1              203 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             SER 
_pdbx_validate_rmsd_angle.auth_seq_id_2              203 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             SER 
_pdbx_validate_rmsd_angle.auth_seq_id_3              203 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                119.73 
_pdbx_validate_rmsd_angle.angle_target_value         110.50 
_pdbx_validate_rmsd_angle.angle_deviation            9.23 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.50 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 97  ? ? 67.88   -4.91   
2  1 THR A 100 ? ? -98.96  35.83   
3  1 SER A 137 ? ? -159.98 89.49   
4  1 ASP A 192 ? ? -57.40  109.05  
5  1 GLN A 197 ? ? 67.81   -5.77   
6  1 SER A 207 ? ? -135.47 -30.66  
7  1 TYR A 209 ? ? -130.63 -30.40  
8  1 ALA A 232 ? ? -92.45  48.82   
9  1 ASP A 233 ? ? 71.20   -12.56  
10 1 LEU A 269 ? ? -97.12  56.79   
11 1 PHE A 387 ? ? -170.04 141.22  
12 1 GLU A 391 ? ? -92.02  54.42   
13 1 LYS A 428 ? ? 92.32   -14.94  
14 1 ALA B 30  ? ? 58.34   9.15    
15 1 VAL B 119 ? ? -101.79 -62.71  
16 1 THR B 160 ? ? -96.45  37.83   
17 1 TYR B 169 ? ? -118.48 -167.82 
18 1 GLN B 192 ? ? 55.69   18.90   
19 1 LEU B 201 ? ? -68.48  -178.29 
20 1 PHE B 247 ? ? -140.49 26.83   
21 1 SER B 256 ? ? -162.16 -168.54 
22 1 ALA B 279 ? ? -141.71 44.11   
23 1 HIS B 280 ? ? -99.34  -60.42  
24 1 PHE B 305 ? ? -160.94 116.76  
25 1 LEU B 311 ? ? 54.72   16.34   
26 1 GLN B 332 ? ? -78.53  -168.85 
27 1 ASN C 43  ? ? -95.03  59.13   
28 1 ILE C 90  ? ? -105.42 -64.75  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9CHU 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9CHU 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.49 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               198582 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX 'calcineurin fused beta2AR in complex with FKBP12' ? ? ? 1,2,3 
2 1 RECOMBINANT        COMPLEX 'calcineurin fused beta2AR'                        ? ? ? 1     
3 1 RECOMBINANT        COMPLEX 'Protein phosphatase 3 catalytic subunit alpha'    ? ? ? 2     
4 1 RECOMBINANT        COMPLEX FKBP1A                                             ? ? ? 3     
# 
_em_imaging.entry_id                        9CHU 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9CHU 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9CHU 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ASP 29  ? A ASP 1   
2  1 Y 1 A GLU 30  ? A GLU 2   
3  1 Y 1 A VAL 31  ? A VAL 3   
4  1 Y 1 B SER 1   ? B SER 1   
5  1 Y 1 B GLU 2   ? B GLU 2   
6  1 Y 1 B PRO 3   ? B PRO 3   
7  1 Y 1 B LYS 4   ? B LYS 4   
8  1 Y 1 B ALA 5   ? B ALA 5   
9  1 Y 1 B ILE 6   ? B ILE 6   
10 1 Y 1 B ASP 7   ? B ASP 7   
11 1 Y 1 B PRO 8   ? B PRO 8   
12 1 Y 1 B LYS 9   ? B LYS 9   
13 1 Y 1 B LEU 10  ? B LEU 10  
14 1 Y 1 B SER 11  ? B SER 11  
15 1 Y 1 B THR 12  ? B THR 12  
16 1 Y 1 B ASN 36  ? B ASN 36  
17 1 Y 1 B ASP 37  ? B ASP 37  
18 1 Y 1 B THR 243 ? B THR 243 
19 1 Y 1 B GLN 244 ? B GLN 244 
20 1 Y 1 B GLU 245 ? B GLU 245 
21 1 Y 1 B ILE 370 ? B ILE 370 
22 1 Y 1 C MET 0   ? C MET 1   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
E5E OAC  O N N 88  
E5E CAJ  C Y N 89  
E5E CAG  C Y N 90  
E5E CAI  C Y N 91  
E5E OAB  O N N 92  
E5E CAE  C Y N 93  
E5E CAF  C Y N 94  
E5E CAK  C Y N 95  
E5E CAL  C N R 96  
E5E OAD  O N N 97  
E5E CAH  C N N 98  
E5E NAA  N N N 99  
E5E HOAC H N N 100 
E5E HAG  H N N 101 
E5E HOAB H N N 102 
E5E HAE  H N N 103 
E5E HAF  H N N 104 
E5E HAL  H N N 105 
E5E HOAD H N N 106 
E5E HAH  H N N 107 
E5E HAHA H N N 108 
E5E HNAA H N N 109 
E5E HNAB H N N 110 
E5E HNAC H N N 111 
FK5 C1   C N N 112 
FK5 C2   C N S 113 
FK5 C3   C N N 114 
FK5 C4   C N N 115 
FK5 C5   C N N 116 
FK5 C6   C N N 117 
FK5 C8   C N N 118 
FK5 C9   C N N 119 
FK5 C10  C N R 120 
FK5 C11  C N R 121 
FK5 C12  C N N 122 
FK5 C13  C N S 123 
FK5 C14  C N R 124 
FK5 C15  C N S 125 
FK5 C16  C N N 126 
FK5 C17  C N S 127 
FK5 C18  C N N 128 
FK5 C19  C N N 129 
FK5 C20  C N N 130 
FK5 C21  C N R 131 
FK5 C22  C N N 132 
FK5 C23  C N N 133 
FK5 C24  C N S 134 
FK5 C25  C N R 135 
FK5 C26  C N S 136 
FK5 C27  C N N 137 
FK5 C28  C N N 138 
FK5 C29  C N R 139 
FK5 C30  C N N 140 
FK5 C31  C N R 141 
FK5 C32  C N R 142 
FK5 C33  C N N 143 
FK5 C34  C N N 144 
FK5 C35  C N N 145 
FK5 C36  C N N 146 
FK5 C37  C N N 147 
FK5 C38  C N N 148 
FK5 C39  C N N 149 
FK5 C40  C N N 150 
FK5 C41  C N N 151 
FK5 C42  C N N 152 
FK5 C43  C N N 153 
FK5 C44  C N N 154 
FK5 C45  C N N 155 
FK5 N7   N N N 156 
FK5 O1   O N N 157 
FK5 O2   O N N 158 
FK5 O3   O N N 159 
FK5 O4   O N N 160 
FK5 O5   O N N 161 
FK5 O6   O N N 162 
FK5 O7   O N N 163 
FK5 O8   O N N 164 
FK5 O9   O N N 165 
FK5 O10  O N N 166 
FK5 O11  O N N 167 
FK5 O12  O N N 168 
FK5 H2   H N N 169 
FK5 H31A H N N 170 
FK5 H32A H N N 171 
FK5 H41  H N N 172 
FK5 H42  H N N 173 
FK5 H51  H N N 174 
FK5 H52  H N N 175 
FK5 H61  H N N 176 
FK5 H62  H N N 177 
FK5 H11  H N N 178 
FK5 H121 H N N 179 
FK5 H122 H N N 180 
FK5 H13  H N N 181 
FK5 H14  H N N 182 
FK5 H15  H N N 183 
FK5 H161 H N N 184 
FK5 H162 H N N 185 
FK5 H17  H N N 186 
FK5 H181 H N N 187 
FK5 H182 H N N 188 
FK5 H20  H N N 189 
FK5 H21  H N N 190 
FK5 H231 H N N 191 
FK5 H232 H N N 192 
FK5 H24  H N N 193 
FK5 H25  H N N 194 
FK5 H26  H N N 195 
FK5 H28  H N N 196 
FK5 H29  H N N 197 
FK5 H301 H N N 198 
FK5 H302 H N N 199 
FK5 H31  H N N 200 
FK5 H32  H N N 201 
FK5 H331 H N N 202 
FK5 H332 H N N 203 
FK5 H341 H N N 204 
FK5 H342 H N N 205 
FK5 H351 H N N 206 
FK5 H352 H N N 207 
FK5 H353 H N N 208 
FK5 H361 H N N 209 
FK5 H362 H N N 210 
FK5 H363 H N N 211 
FK5 H371 H N N 212 
FK5 H372 H N N 213 
FK5 H373 H N N 214 
FK5 H381 H N N 215 
FK5 H382 H N N 216 
FK5 H39  H N N 217 
FK5 H401 H N N 218 
FK5 H402 H N N 219 
FK5 H411 H N N 220 
FK5 H412 H N N 221 
FK5 H413 H N N 222 
FK5 H421 H N N 223 
FK5 H422 H N N 224 
FK5 H423 H N N 225 
FK5 H431 H N N 226 
FK5 H432 H N N 227 
FK5 H433 H N N 228 
FK5 H441 H N N 229 
FK5 H442 H N N 230 
FK5 H443 H N N 231 
FK5 H451 H N N 232 
FK5 H452 H N N 233 
FK5 H453 H N N 234 
FK5 HO6  H N N 235 
FK5 HO10 H N N 236 
FK5 HO12 H N N 237 
GLN N    N N N 238 
GLN CA   C N S 239 
GLN C    C N N 240 
GLN O    O N N 241 
GLN CB   C N N 242 
GLN CG   C N N 243 
GLN CD   C N N 244 
GLN OE1  O N N 245 
GLN NE2  N N N 246 
GLN OXT  O N N 247 
GLN H    H N N 248 
GLN H2   H N N 249 
GLN HA   H N N 250 
GLN HB2  H N N 251 
GLN HB3  H N N 252 
GLN HG2  H N N 253 
GLN HG3  H N N 254 
GLN HE21 H N N 255 
GLN HE22 H N N 256 
GLN HXT  H N N 257 
GLU N    N N N 258 
GLU CA   C N S 259 
GLU C    C N N 260 
GLU O    O N N 261 
GLU CB   C N N 262 
GLU CG   C N N 263 
GLU CD   C N N 264 
GLU OE1  O N N 265 
GLU OE2  O N N 266 
GLU OXT  O N N 267 
GLU H    H N N 268 
GLU H2   H N N 269 
GLU HA   H N N 270 
GLU HB2  H N N 271 
GLU HB3  H N N 272 
GLU HG2  H N N 273 
GLU HG3  H N N 274 
GLU HE2  H N N 275 
GLU HXT  H N N 276 
GLY N    N N N 277 
GLY CA   C N N 278 
GLY C    C N N 279 
GLY O    O N N 280 
GLY OXT  O N N 281 
GLY H    H N N 282 
GLY H2   H N N 283 
GLY HA2  H N N 284 
GLY HA3  H N N 285 
GLY HXT  H N N 286 
HIS N    N N N 287 
HIS CA   C N S 288 
HIS C    C N N 289 
HIS O    O N N 290 
HIS CB   C N N 291 
HIS CG   C Y N 292 
HIS ND1  N Y N 293 
HIS CD2  C Y N 294 
HIS CE1  C Y N 295 
HIS NE2  N Y N 296 
HIS OXT  O N N 297 
HIS H    H N N 298 
HIS H2   H N N 299 
HIS HA   H N N 300 
HIS HB2  H N N 301 
HIS HB3  H N N 302 
HIS HD1  H N N 303 
HIS HD2  H N N 304 
HIS HE1  H N N 305 
HIS HE2  H N N 306 
HIS HXT  H N N 307 
ILE N    N N N 308 
ILE CA   C N S 309 
ILE C    C N N 310 
ILE O    O N N 311 
ILE CB   C N S 312 
ILE CG1  C N N 313 
ILE CG2  C N N 314 
ILE CD1  C N N 315 
ILE OXT  O N N 316 
ILE H    H N N 317 
ILE H2   H N N 318 
ILE HA   H N N 319 
ILE HB   H N N 320 
ILE HG12 H N N 321 
ILE HG13 H N N 322 
ILE HG21 H N N 323 
ILE HG22 H N N 324 
ILE HG23 H N N 325 
ILE HD11 H N N 326 
ILE HD12 H N N 327 
ILE HD13 H N N 328 
ILE HXT  H N N 329 
LEU N    N N N 330 
LEU CA   C N S 331 
LEU C    C N N 332 
LEU O    O N N 333 
LEU CB   C N N 334 
LEU CG   C N N 335 
LEU CD1  C N N 336 
LEU CD2  C N N 337 
LEU OXT  O N N 338 
LEU H    H N N 339 
LEU H2   H N N 340 
LEU HA   H N N 341 
LEU HB2  H N N 342 
LEU HB3  H N N 343 
LEU HG   H N N 344 
LEU HD11 H N N 345 
LEU HD12 H N N 346 
LEU HD13 H N N 347 
LEU HD21 H N N 348 
LEU HD22 H N N 349 
LEU HD23 H N N 350 
LEU HXT  H N N 351 
LYS N    N N N 352 
LYS CA   C N S 353 
LYS C    C N N 354 
LYS O    O N N 355 
LYS CB   C N N 356 
LYS CG   C N N 357 
LYS CD   C N N 358 
LYS CE   C N N 359 
LYS NZ   N N N 360 
LYS OXT  O N N 361 
LYS H    H N N 362 
LYS H2   H N N 363 
LYS HA   H N N 364 
LYS HB2  H N N 365 
LYS HB3  H N N 366 
LYS HG2  H N N 367 
LYS HG3  H N N 368 
LYS HD2  H N N 369 
LYS HD3  H N N 370 
LYS HE2  H N N 371 
LYS HE3  H N N 372 
LYS HZ1  H N N 373 
LYS HZ2  H N N 374 
LYS HZ3  H N N 375 
LYS HXT  H N N 376 
MET N    N N N 377 
MET CA   C N S 378 
MET C    C N N 379 
MET O    O N N 380 
MET CB   C N N 381 
MET CG   C N N 382 
MET SD   S N N 383 
MET CE   C N N 384 
MET OXT  O N N 385 
MET H    H N N 386 
MET H2   H N N 387 
MET HA   H N N 388 
MET HB2  H N N 389 
MET HB3  H N N 390 
MET HG2  H N N 391 
MET HG3  H N N 392 
MET HE1  H N N 393 
MET HE2  H N N 394 
MET HE3  H N N 395 
MET HXT  H N N 396 
PHE N    N N N 397 
PHE CA   C N S 398 
PHE C    C N N 399 
PHE O    O N N 400 
PHE CB   C N N 401 
PHE CG   C Y N 402 
PHE CD1  C Y N 403 
PHE CD2  C Y N 404 
PHE CE1  C Y N 405 
PHE CE2  C Y N 406 
PHE CZ   C Y N 407 
PHE OXT  O N N 408 
PHE H    H N N 409 
PHE H2   H N N 410 
PHE HA   H N N 411 
PHE HB2  H N N 412 
PHE HB3  H N N 413 
PHE HD1  H N N 414 
PHE HD2  H N N 415 
PHE HE1  H N N 416 
PHE HE2  H N N 417 
PHE HZ   H N N 418 
PHE HXT  H N N 419 
PRO N    N N N 420 
PRO CA   C N S 421 
PRO C    C N N 422 
PRO O    O N N 423 
PRO CB   C N N 424 
PRO CG   C N N 425 
PRO CD   C N N 426 
PRO OXT  O N N 427 
PRO H    H N N 428 
PRO HA   H N N 429 
PRO HB2  H N N 430 
PRO HB3  H N N 431 
PRO HG2  H N N 432 
PRO HG3  H N N 433 
PRO HD2  H N N 434 
PRO HD3  H N N 435 
PRO HXT  H N N 436 
SER N    N N N 437 
SER CA   C N S 438 
SER C    C N N 439 
SER O    O N N 440 
SER CB   C N N 441 
SER OG   O N N 442 
SER OXT  O N N 443 
SER H    H N N 444 
SER H2   H N N 445 
SER HA   H N N 446 
SER HB2  H N N 447 
SER HB3  H N N 448 
SER HG   H N N 449 
SER HXT  H N N 450 
THR N    N N N 451 
THR CA   C N S 452 
THR C    C N N 453 
THR O    O N N 454 
THR CB   C N R 455 
THR OG1  O N N 456 
THR CG2  C N N 457 
THR OXT  O N N 458 
THR H    H N N 459 
THR H2   H N N 460 
THR HA   H N N 461 
THR HB   H N N 462 
THR HG1  H N N 463 
THR HG21 H N N 464 
THR HG22 H N N 465 
THR HG23 H N N 466 
THR HXT  H N N 467 
TRP N    N N N 468 
TRP CA   C N S 469 
TRP C    C N N 470 
TRP O    O N N 471 
TRP CB   C N N 472 
TRP CG   C Y N 473 
TRP CD1  C Y N 474 
TRP CD2  C Y N 475 
TRP NE1  N Y N 476 
TRP CE2  C Y N 477 
TRP CE3  C Y N 478 
TRP CZ2  C Y N 479 
TRP CZ3  C Y N 480 
TRP CH2  C Y N 481 
TRP OXT  O N N 482 
TRP H    H N N 483 
TRP H2   H N N 484 
TRP HA   H N N 485 
TRP HB2  H N N 486 
TRP HB3  H N N 487 
TRP HD1  H N N 488 
TRP HE1  H N N 489 
TRP HE3  H N N 490 
TRP HZ2  H N N 491 
TRP HZ3  H N N 492 
TRP HH2  H N N 493 
TRP HXT  H N N 494 
TYR N    N N N 495 
TYR CA   C N S 496 
TYR C    C N N 497 
TYR O    O N N 498 
TYR CB   C N N 499 
TYR CG   C Y N 500 
TYR CD1  C Y N 501 
TYR CD2  C Y N 502 
TYR CE1  C Y N 503 
TYR CE2  C Y N 504 
TYR CZ   C Y N 505 
TYR OH   O N N 506 
TYR OXT  O N N 507 
TYR H    H N N 508 
TYR H2   H N N 509 
TYR HA   H N N 510 
TYR HB2  H N N 511 
TYR HB3  H N N 512 
TYR HD1  H N N 513 
TYR HD2  H N N 514 
TYR HE1  H N N 515 
TYR HE2  H N N 516 
TYR HH   H N N 517 
TYR HXT  H N N 518 
VAL N    N N N 519 
VAL CA   C N S 520 
VAL C    C N N 521 
VAL O    O N N 522 
VAL CB   C N N 523 
VAL CG1  C N N 524 
VAL CG2  C N N 525 
VAL OXT  O N N 526 
VAL H    H N N 527 
VAL H2   H N N 528 
VAL HA   H N N 529 
VAL HB   H N N 530 
VAL HG11 H N N 531 
VAL HG12 H N N 532 
VAL HG13 H N N 533 
VAL HG21 H N N 534 
VAL HG22 H N N 535 
VAL HG23 H N N 536 
VAL HXT  H N N 537 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
E5E OAD CAL  sing N N 83  
E5E CAL CAK  sing N N 84  
E5E CAL CAH  sing N N 85  
E5E CAK CAF  doub Y N 86  
E5E CAK CAG  sing Y N 87  
E5E CAF CAE  sing Y N 88  
E5E CAG CAJ  doub Y N 89  
E5E CAE CAI  doub Y N 90  
E5E CAJ CAI  sing Y N 91  
E5E CAJ OAC  sing N N 92  
E5E CAI OAB  sing N N 93  
E5E CAH NAA  sing N N 94  
E5E OAC HOAC sing N N 95  
E5E CAG HAG  sing N N 96  
E5E OAB HOAB sing N N 97  
E5E CAE HAE  sing N N 98  
E5E CAF HAF  sing N N 99  
E5E CAL HAL  sing N N 100 
E5E OAD HOAD sing N N 101 
E5E CAH HAH  sing N N 102 
E5E CAH HAHA sing N N 103 
E5E NAA HNAA sing N N 104 
E5E NAA HNAB sing N N 105 
E5E NAA HNAC sing N N 106 
FK5 C1  C2   sing N N 107 
FK5 C1  O1   sing N N 108 
FK5 C1  O2   doub N N 109 
FK5 C2  C3   sing N N 110 
FK5 C2  N7   sing N N 111 
FK5 C2  H2   sing N N 112 
FK5 C3  C4   sing N N 113 
FK5 C3  H31A sing N N 114 
FK5 C3  H32A sing N N 115 
FK5 C4  C5   sing N N 116 
FK5 C4  H41  sing N N 117 
FK5 C4  H42  sing N N 118 
FK5 C5  C6   sing N N 119 
FK5 C5  H51  sing N N 120 
FK5 C5  H52  sing N N 121 
FK5 C6  N7   sing N N 122 
FK5 C6  H61  sing N N 123 
FK5 C6  H62  sing N N 124 
FK5 C8  C9   sing N N 125 
FK5 C8  N7   sing N N 126 
FK5 C8  O3   doub N N 127 
FK5 C9  C10  sing N N 128 
FK5 C9  O4   doub N N 129 
FK5 C10 C11  sing N N 130 
FK5 C10 O5   sing N N 131 
FK5 C10 O6   sing N N 132 
FK5 C11 C12  sing N N 133 
FK5 C11 C35  sing N N 134 
FK5 C11 H11  sing N N 135 
FK5 C12 C13  sing N N 136 
FK5 C12 H121 sing N N 137 
FK5 C12 H122 sing N N 138 
FK5 C13 C14  sing N N 139 
FK5 C13 O7   sing N N 140 
FK5 C13 H13  sing N N 141 
FK5 C14 C15  sing N N 142 
FK5 C14 O5   sing N N 143 
FK5 C14 H14  sing N N 144 
FK5 C15 C16  sing N N 145 
FK5 C15 O8   sing N N 146 
FK5 C15 H15  sing N N 147 
FK5 C16 C17  sing N N 148 
FK5 C16 H161 sing N N 149 
FK5 C16 H162 sing N N 150 
FK5 C17 C18  sing N N 151 
FK5 C17 C36  sing N N 152 
FK5 C17 H17  sing N N 153 
FK5 C18 C19  sing N N 154 
FK5 C18 H181 sing N N 155 
FK5 C18 H182 sing N N 156 
FK5 C19 C20  doub N E 157 
FK5 C19 C37  sing N N 158 
FK5 C20 C21  sing N N 159 
FK5 C20 H20  sing N N 160 
FK5 C21 C22  sing N N 161 
FK5 C21 C38  sing N N 162 
FK5 C21 H21  sing N N 163 
FK5 C22 C23  sing N N 164 
FK5 C22 O9   doub N N 165 
FK5 C23 C24  sing N N 166 
FK5 C23 H231 sing N N 167 
FK5 C23 H232 sing N N 168 
FK5 C24 C25  sing N N 169 
FK5 C24 O10  sing N N 170 
FK5 C24 H24  sing N N 171 
FK5 C25 C26  sing N N 172 
FK5 C25 C41  sing N N 173 
FK5 C25 H25  sing N N 174 
FK5 C26 C27  sing N N 175 
FK5 C26 O1   sing N N 176 
FK5 C26 H26  sing N N 177 
FK5 C27 C28  doub N E 178 
FK5 C27 C42  sing N N 179 
FK5 C28 C29  sing N N 180 
FK5 C28 H28  sing N N 181 
FK5 C29 C30  sing N N 182 
FK5 C29 C34  sing N N 183 
FK5 C29 H29  sing N N 184 
FK5 C30 C31  sing N N 185 
FK5 C30 H301 sing N N 186 
FK5 C30 H302 sing N N 187 
FK5 C31 C32  sing N N 188 
FK5 C31 O11  sing N N 189 
FK5 C31 H31  sing N N 190 
FK5 C32 C33  sing N N 191 
FK5 C32 O12  sing N N 192 
FK5 C32 H32  sing N N 193 
FK5 C33 C34  sing N N 194 
FK5 C33 H331 sing N N 195 
FK5 C33 H332 sing N N 196 
FK5 C34 H341 sing N N 197 
FK5 C34 H342 sing N N 198 
FK5 C35 H351 sing N N 199 
FK5 C35 H352 sing N N 200 
FK5 C35 H353 sing N N 201 
FK5 C36 H361 sing N N 202 
FK5 C36 H362 sing N N 203 
FK5 C36 H363 sing N N 204 
FK5 C37 H371 sing N N 205 
FK5 C37 H372 sing N N 206 
FK5 C37 H373 sing N N 207 
FK5 C38 C39  sing N N 208 
FK5 C38 H381 sing N N 209 
FK5 C38 H382 sing N N 210 
FK5 C39 C40  doub N N 211 
FK5 C39 H39  sing N N 212 
FK5 C40 H401 sing N N 213 
FK5 C40 H402 sing N N 214 
FK5 C41 H411 sing N N 215 
FK5 C41 H412 sing N N 216 
FK5 C41 H413 sing N N 217 
FK5 C42 H421 sing N N 218 
FK5 C42 H422 sing N N 219 
FK5 C42 H423 sing N N 220 
FK5 C43 O7   sing N N 221 
FK5 C43 H431 sing N N 222 
FK5 C43 H432 sing N N 223 
FK5 C43 H433 sing N N 224 
FK5 C44 O8   sing N N 225 
FK5 C44 H441 sing N N 226 
FK5 C44 H442 sing N N 227 
FK5 C44 H443 sing N N 228 
FK5 C45 O11  sing N N 229 
FK5 C45 H451 sing N N 230 
FK5 C45 H452 sing N N 231 
FK5 C45 H453 sing N N 232 
FK5 O6  HO6  sing N N 233 
FK5 O10 HO10 sing N N 234 
FK5 O12 HO12 sing N N 235 
GLN N   CA   sing N N 236 
GLN N   H    sing N N 237 
GLN N   H2   sing N N 238 
GLN CA  C    sing N N 239 
GLN CA  CB   sing N N 240 
GLN CA  HA   sing N N 241 
GLN C   O    doub N N 242 
GLN C   OXT  sing N N 243 
GLN CB  CG   sing N N 244 
GLN CB  HB2  sing N N 245 
GLN CB  HB3  sing N N 246 
GLN CG  CD   sing N N 247 
GLN CG  HG2  sing N N 248 
GLN CG  HG3  sing N N 249 
GLN CD  OE1  doub N N 250 
GLN CD  NE2  sing N N 251 
GLN NE2 HE21 sing N N 252 
GLN NE2 HE22 sing N N 253 
GLN OXT HXT  sing N N 254 
GLU N   CA   sing N N 255 
GLU N   H    sing N N 256 
GLU N   H2   sing N N 257 
GLU CA  C    sing N N 258 
GLU CA  CB   sing N N 259 
GLU CA  HA   sing N N 260 
GLU C   O    doub N N 261 
GLU C   OXT  sing N N 262 
GLU CB  CG   sing N N 263 
GLU CB  HB2  sing N N 264 
GLU CB  HB3  sing N N 265 
GLU CG  CD   sing N N 266 
GLU CG  HG2  sing N N 267 
GLU CG  HG3  sing N N 268 
GLU CD  OE1  doub N N 269 
GLU CD  OE2  sing N N 270 
GLU OE2 HE2  sing N N 271 
GLU OXT HXT  sing N N 272 
GLY N   CA   sing N N 273 
GLY N   H    sing N N 274 
GLY N   H2   sing N N 275 
GLY CA  C    sing N N 276 
GLY CA  HA2  sing N N 277 
GLY CA  HA3  sing N N 278 
GLY C   O    doub N N 279 
GLY C   OXT  sing N N 280 
GLY OXT HXT  sing N N 281 
HIS N   CA   sing N N 282 
HIS N   H    sing N N 283 
HIS N   H2   sing N N 284 
HIS CA  C    sing N N 285 
HIS CA  CB   sing N N 286 
HIS CA  HA   sing N N 287 
HIS C   O    doub N N 288 
HIS C   OXT  sing N N 289 
HIS CB  CG   sing N N 290 
HIS CB  HB2  sing N N 291 
HIS CB  HB3  sing N N 292 
HIS CG  ND1  sing Y N 293 
HIS CG  CD2  doub Y N 294 
HIS ND1 CE1  doub Y N 295 
HIS ND1 HD1  sing N N 296 
HIS CD2 NE2  sing Y N 297 
HIS CD2 HD2  sing N N 298 
HIS CE1 NE2  sing Y N 299 
HIS CE1 HE1  sing N N 300 
HIS NE2 HE2  sing N N 301 
HIS OXT HXT  sing N N 302 
ILE N   CA   sing N N 303 
ILE N   H    sing N N 304 
ILE N   H2   sing N N 305 
ILE CA  C    sing N N 306 
ILE CA  CB   sing N N 307 
ILE CA  HA   sing N N 308 
ILE C   O    doub N N 309 
ILE C   OXT  sing N N 310 
ILE CB  CG1  sing N N 311 
ILE CB  CG2  sing N N 312 
ILE CB  HB   sing N N 313 
ILE CG1 CD1  sing N N 314 
ILE CG1 HG12 sing N N 315 
ILE CG1 HG13 sing N N 316 
ILE CG2 HG21 sing N N 317 
ILE CG2 HG22 sing N N 318 
ILE CG2 HG23 sing N N 319 
ILE CD1 HD11 sing N N 320 
ILE CD1 HD12 sing N N 321 
ILE CD1 HD13 sing N N 322 
ILE OXT HXT  sing N N 323 
LEU N   CA   sing N N 324 
LEU N   H    sing N N 325 
LEU N   H2   sing N N 326 
LEU CA  C    sing N N 327 
LEU CA  CB   sing N N 328 
LEU CA  HA   sing N N 329 
LEU C   O    doub N N 330 
LEU C   OXT  sing N N 331 
LEU CB  CG   sing N N 332 
LEU CB  HB2  sing N N 333 
LEU CB  HB3  sing N N 334 
LEU CG  CD1  sing N N 335 
LEU CG  CD2  sing N N 336 
LEU CG  HG   sing N N 337 
LEU CD1 HD11 sing N N 338 
LEU CD1 HD12 sing N N 339 
LEU CD1 HD13 sing N N 340 
LEU CD2 HD21 sing N N 341 
LEU CD2 HD22 sing N N 342 
LEU CD2 HD23 sing N N 343 
LEU OXT HXT  sing N N 344 
LYS N   CA   sing N N 345 
LYS N   H    sing N N 346 
LYS N   H2   sing N N 347 
LYS CA  C    sing N N 348 
LYS CA  CB   sing N N 349 
LYS CA  HA   sing N N 350 
LYS C   O    doub N N 351 
LYS C   OXT  sing N N 352 
LYS CB  CG   sing N N 353 
LYS CB  HB2  sing N N 354 
LYS CB  HB3  sing N N 355 
LYS CG  CD   sing N N 356 
LYS CG  HG2  sing N N 357 
LYS CG  HG3  sing N N 358 
LYS CD  CE   sing N N 359 
LYS CD  HD2  sing N N 360 
LYS CD  HD3  sing N N 361 
LYS CE  NZ   sing N N 362 
LYS CE  HE2  sing N N 363 
LYS CE  HE3  sing N N 364 
LYS NZ  HZ1  sing N N 365 
LYS NZ  HZ2  sing N N 366 
LYS NZ  HZ3  sing N N 367 
LYS OXT HXT  sing N N 368 
MET N   CA   sing N N 369 
MET N   H    sing N N 370 
MET N   H2   sing N N 371 
MET CA  C    sing N N 372 
MET CA  CB   sing N N 373 
MET CA  HA   sing N N 374 
MET C   O    doub N N 375 
MET C   OXT  sing N N 376 
MET CB  CG   sing N N 377 
MET CB  HB2  sing N N 378 
MET CB  HB3  sing N N 379 
MET CG  SD   sing N N 380 
MET CG  HG2  sing N N 381 
MET CG  HG3  sing N N 382 
MET SD  CE   sing N N 383 
MET CE  HE1  sing N N 384 
MET CE  HE2  sing N N 385 
MET CE  HE3  sing N N 386 
MET OXT HXT  sing N N 387 
PHE N   CA   sing N N 388 
PHE N   H    sing N N 389 
PHE N   H2   sing N N 390 
PHE CA  C    sing N N 391 
PHE CA  CB   sing N N 392 
PHE CA  HA   sing N N 393 
PHE C   O    doub N N 394 
PHE C   OXT  sing N N 395 
PHE CB  CG   sing N N 396 
PHE CB  HB2  sing N N 397 
PHE CB  HB3  sing N N 398 
PHE CG  CD1  doub Y N 399 
PHE CG  CD2  sing Y N 400 
PHE CD1 CE1  sing Y N 401 
PHE CD1 HD1  sing N N 402 
PHE CD2 CE2  doub Y N 403 
PHE CD2 HD2  sing N N 404 
PHE CE1 CZ   doub Y N 405 
PHE CE1 HE1  sing N N 406 
PHE CE2 CZ   sing Y N 407 
PHE CE2 HE2  sing N N 408 
PHE CZ  HZ   sing N N 409 
PHE OXT HXT  sing N N 410 
PRO N   CA   sing N N 411 
PRO N   CD   sing N N 412 
PRO N   H    sing N N 413 
PRO CA  C    sing N N 414 
PRO CA  CB   sing N N 415 
PRO CA  HA   sing N N 416 
PRO C   O    doub N N 417 
PRO C   OXT  sing N N 418 
PRO CB  CG   sing N N 419 
PRO CB  HB2  sing N N 420 
PRO CB  HB3  sing N N 421 
PRO CG  CD   sing N N 422 
PRO CG  HG2  sing N N 423 
PRO CG  HG3  sing N N 424 
PRO CD  HD2  sing N N 425 
PRO CD  HD3  sing N N 426 
PRO OXT HXT  sing N N 427 
SER N   CA   sing N N 428 
SER N   H    sing N N 429 
SER N   H2   sing N N 430 
SER CA  C    sing N N 431 
SER CA  CB   sing N N 432 
SER CA  HA   sing N N 433 
SER C   O    doub N N 434 
SER C   OXT  sing N N 435 
SER CB  OG   sing N N 436 
SER CB  HB2  sing N N 437 
SER CB  HB3  sing N N 438 
SER OG  HG   sing N N 439 
SER OXT HXT  sing N N 440 
THR N   CA   sing N N 441 
THR N   H    sing N N 442 
THR N   H2   sing N N 443 
THR CA  C    sing N N 444 
THR CA  CB   sing N N 445 
THR CA  HA   sing N N 446 
THR C   O    doub N N 447 
THR C   OXT  sing N N 448 
THR CB  OG1  sing N N 449 
THR CB  CG2  sing N N 450 
THR CB  HB   sing N N 451 
THR OG1 HG1  sing N N 452 
THR CG2 HG21 sing N N 453 
THR CG2 HG22 sing N N 454 
THR CG2 HG23 sing N N 455 
THR OXT HXT  sing N N 456 
TRP N   CA   sing N N 457 
TRP N   H    sing N N 458 
TRP N   H2   sing N N 459 
TRP CA  C    sing N N 460 
TRP CA  CB   sing N N 461 
TRP CA  HA   sing N N 462 
TRP C   O    doub N N 463 
TRP C   OXT  sing N N 464 
TRP CB  CG   sing N N 465 
TRP CB  HB2  sing N N 466 
TRP CB  HB3  sing N N 467 
TRP CG  CD1  doub Y N 468 
TRP CG  CD2  sing Y N 469 
TRP CD1 NE1  sing Y N 470 
TRP CD1 HD1  sing N N 471 
TRP CD2 CE2  doub Y N 472 
TRP CD2 CE3  sing Y N 473 
TRP NE1 CE2  sing Y N 474 
TRP NE1 HE1  sing N N 475 
TRP CE2 CZ2  sing Y N 476 
TRP CE3 CZ3  doub Y N 477 
TRP CE3 HE3  sing N N 478 
TRP CZ2 CH2  doub Y N 479 
TRP CZ2 HZ2  sing N N 480 
TRP CZ3 CH2  sing Y N 481 
TRP CZ3 HZ3  sing N N 482 
TRP CH2 HH2  sing N N 483 
TRP OXT HXT  sing N N 484 
TYR N   CA   sing N N 485 
TYR N   H    sing N N 486 
TYR N   H2   sing N N 487 
TYR CA  C    sing N N 488 
TYR CA  CB   sing N N 489 
TYR CA  HA   sing N N 490 
TYR C   O    doub N N 491 
TYR C   OXT  sing N N 492 
TYR CB  CG   sing N N 493 
TYR CB  HB2  sing N N 494 
TYR CB  HB3  sing N N 495 
TYR CG  CD1  doub Y N 496 
TYR CG  CD2  sing Y N 497 
TYR CD1 CE1  sing Y N 498 
TYR CD1 HD1  sing N N 499 
TYR CD2 CE2  doub Y N 500 
TYR CD2 HD2  sing N N 501 
TYR CE1 CZ   doub Y N 502 
TYR CE1 HE1  sing N N 503 
TYR CE2 CZ   sing Y N 504 
TYR CE2 HE2  sing N N 505 
TYR CZ  OH   sing N N 506 
TYR OH  HH   sing N N 507 
TYR OXT HXT  sing N N 508 
VAL N   CA   sing N N 509 
VAL N   H    sing N N 510 
VAL N   H2   sing N N 511 
VAL CA  C    sing N N 512 
VAL CA  CB   sing N N 513 
VAL CA  HA   sing N N 514 
VAL C   O    doub N N 515 
VAL C   OXT  sing N N 516 
VAL CB  CG1  sing N N 517 
VAL CB  CG2  sing N N 518 
VAL CB  HB   sing N N 519 
VAL CG1 HG11 sing N N 520 
VAL CG1 HG12 sing N N 521 
VAL CG1 HG13 sing N N 522 
VAL CG2 HG21 sing N N 523 
VAL CG2 HG22 sing N N 524 
VAL CG2 HG23 sing N N 525 
VAL OXT HXT  sing N N 526 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-02 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9CHU 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-13 
_em_admin.title              
'Cryo-EM structure of calcineurin fused beta2 adrenergic receptor in norepinephrine bound inactive state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 9606  'Homo sapiens' ? ? ? ? ? 
? ? 3 3 10090 'Mus musculus' ? ? ? ? ? 
? ? 4 4 9606  'Homo sapiens' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 2 2 7108   'Spodoptera frugiperda'                     ? ? 
? 3 3 7108   'Spodoptera frugiperda'                     ? ? 
? 4 4 866768 
;Escherichia coli 'BL21-Gold(DE3)pLysS AG'
;
? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         53 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 QUANTUM (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.18_3861: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?          
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?          
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?          
CLASSIFICATION                  ? 5  1 1 1 ?      ?          
MASKING                         ? 6  1 1 1 ?      ?          
RECONSTRUCTION                  ? 7  1 1 1 ?      ?          
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?          
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?          
'CTF CORRECTION'                ? 10 1 1 1 ?      ?          
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?          
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?          
'MODEL FITTING'                 ? 13 1 1 1 ?      ?          
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?          
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?          
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?          
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?          
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?          
OTHER                           ? 19 1 1 1 ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9CHU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . TRP A 1 4   ? 193.352 161.115 123.656 1.00 84.14 ? 32  TRP A N   1 
ATOM   2    C CA  . TRP A 1 4   ? 193.660 159.694 123.561 1.00 84.14 ? 32  TRP A CA  1 
ATOM   3    C C   . TRP A 1 4   ? 192.660 158.871 124.365 1.00 84.14 ? 32  TRP A C   1 
ATOM   4    O O   . TRP A 1 4   ? 191.954 159.402 125.219 1.00 84.14 ? 32  TRP A O   1 
ATOM   5    C CB  . TRP A 1 4   ? 195.085 159.420 124.043 1.00 84.14 ? 32  TRP A CB  1 
ATOM   6    N N   . VAL A 1 5   ? 192.616 157.566 124.085 1.00 78.85 ? 33  VAL A N   1 
ATOM   7    C CA  . VAL A 1 5   ? 191.621 156.695 124.705 1.00 78.85 ? 33  VAL A CA  1 
ATOM   8    C C   . VAL A 1 5   ? 191.818 156.632 126.215 1.00 78.85 ? 33  VAL A C   1 
ATOM   9    O O   . VAL A 1 5   ? 190.852 156.701 126.986 1.00 78.85 ? 33  VAL A O   1 
ATOM   10   C CB  . VAL A 1 5   ? 191.673 155.295 124.066 1.00 78.85 ? 33  VAL A CB  1 
ATOM   11   C CG1 . VAL A 1 5   ? 190.586 154.405 124.642 1.00 78.85 ? 33  VAL A CG1 1 
ATOM   12   C CG2 . VAL A 1 5   ? 191.538 155.400 122.557 1.00 78.85 ? 33  VAL A CG2 1 
ATOM   13   N N   . VAL A 1 6   ? 193.069 156.495 126.662 1.00 73.71 ? 34  VAL A N   1 
ATOM   14   C CA  . VAL A 1 6   ? 193.340 156.376 128.093 1.00 73.71 ? 34  VAL A CA  1 
ATOM   15   C C   . VAL A 1 6   ? 192.908 157.639 128.826 1.00 73.71 ? 34  VAL A C   1 
ATOM   16   O O   . VAL A 1 6   ? 192.356 157.574 129.932 1.00 73.71 ? 34  VAL A O   1 
ATOM   17   C CB  . VAL A 1 6   ? 194.829 156.065 128.330 1.00 73.71 ? 34  VAL A CB  1 
ATOM   18   N N   . GLY A 1 7   ? 193.161 158.805 128.231 1.00 69.88 ? 35  GLY A N   1 
ATOM   19   C CA  . GLY A 1 7   ? 192.744 160.049 128.858 1.00 69.88 ? 35  GLY A CA  1 
ATOM   20   C C   . GLY A 1 7   ? 191.238 160.157 129.001 1.00 69.88 ? 35  GLY A C   1 
ATOM   21   O O   . GLY A 1 7   ? 190.733 160.562 130.051 1.00 69.88 ? 35  GLY A O   1 
ATOM   22   N N   . MET A 1 8   ? 190.500 159.797 127.948 1.00 72.73 ? 36  MET A N   1 
ATOM   23   C CA  . MET A 1 8   ? 189.044 159.808 128.036 1.00 72.73 ? 36  MET A CA  1 
ATOM   24   C C   . MET A 1 8   ? 188.554 158.839 129.104 1.00 72.73 ? 36  MET A C   1 
ATOM   25   O O   . MET A 1 8   ? 187.647 159.167 129.878 1.00 72.73 ? 36  MET A O   1 
ATOM   26   C CB  . MET A 1 8   ? 188.426 159.468 126.680 1.00 72.73 ? 36  MET A CB  1 
ATOM   27   C CG  . MET A 1 8   ? 188.973 160.279 125.520 1.00 72.73 ? 36  MET A CG  1 
ATOM   28   S SD  . MET A 1 8   ? 187.729 160.641 124.266 1.00 72.73 ? 36  MET A SD  1 
ATOM   29   C CE  . MET A 1 8   ? 187.034 162.163 124.902 1.00 72.73 ? 36  MET A CE  1 
ATOM   30   N N   . GLY A 1 9   ? 189.142 157.641 129.161 1.00 64.67 ? 37  GLY A N   1 
ATOM   31   C CA  . GLY A 1 9   ? 188.747 156.688 130.187 1.00 64.67 ? 37  GLY A CA  1 
ATOM   32   C C   . GLY A 1 9   ? 188.996 157.209 131.590 1.00 64.67 ? 37  GLY A C   1 
ATOM   33   O O   . GLY A 1 9   ? 188.156 157.050 132.481 1.00 64.67 ? 37  GLY A O   1 
ATOM   34   N N   . ILE A 1 10  ? 190.148 157.850 131.800 1.00 61.92 ? 38  ILE A N   1 
ATOM   35   C CA  . ILE A 1 10  ? 190.455 158.429 133.105 1.00 61.92 ? 38  ILE A CA  1 
ATOM   36   C C   . ILE A 1 10  ? 189.465 159.536 133.444 1.00 61.92 ? 38  ILE A C   1 
ATOM   37   O O   . ILE A 1 10  ? 189.016 159.659 134.591 1.00 61.92 ? 38  ILE A O   1 
ATOM   38   C CB  . ILE A 1 10  ? 191.907 158.939 133.134 1.00 61.92 ? 38  ILE A CB  1 
ATOM   39   N N   . VAL A 1 11  ? 189.116 160.362 132.456 1.00 57.53 ? 39  VAL A N   1 
ATOM   40   C CA  . VAL A 1 11  ? 188.175 161.453 132.695 1.00 57.53 ? 39  VAL A CA  1 
ATOM   41   C C   . VAL A 1 11  ? 186.816 160.901 133.110 1.00 57.53 ? 39  VAL A C   1 
ATOM   42   O O   . VAL A 1 11  ? 186.197 161.384 134.065 1.00 57.53 ? 39  VAL A O   1 
ATOM   43   C CB  . VAL A 1 11  ? 188.066 162.347 131.448 1.00 57.53 ? 39  VAL A CB  1 
ATOM   44   C CG1 . VAL A 1 11  ? 186.828 163.226 131.527 1.00 57.53 ? 39  VAL A CG1 1 
ATOM   45   C CG2 . VAL A 1 11  ? 189.315 163.195 131.302 1.00 57.53 ? 39  VAL A CG2 1 
ATOM   46   N N   . MET A 1 12  ? 186.334 159.878 132.398 1.00 55.55 ? 40  MET A N   1 
ATOM   47   C CA  . MET A 1 12  ? 185.044 159.287 132.750 1.00 55.55 ? 40  MET A CA  1 
ATOM   48   C C   . MET A 1 12  ? 185.087 158.640 134.127 1.00 55.55 ? 40  MET A C   1 
ATOM   49   O O   . MET A 1 12  ? 184.123 158.740 134.896 1.00 55.55 ? 40  MET A O   1 
ATOM   50   C CB  . MET A 1 12  ? 184.606 158.269 131.697 1.00 55.55 ? 40  MET A CB  1 
ATOM   51   C CG  . MET A 1 12  ? 184.688 158.754 130.263 1.00 55.55 ? 40  MET A CG  1 
ATOM   52   S SD  . MET A 1 12  ? 184.309 160.504 130.078 1.00 55.55 ? 40  MET A SD  1 
ATOM   53   C CE  . MET A 1 12  ? 184.275 160.646 128.295 1.00 55.55 ? 40  MET A CE  1 
ATOM   54   N N   . SER A 1 13  ? 186.190 157.962 134.454 1.00 58.12 ? 41  SER A N   1 
ATOM   55   C CA  . SER A 1 13  ? 186.314 157.353 135.775 1.00 58.12 ? 41  SER A CA  1 
ATOM   56   C C   . SER A 1 13  ? 186.258 158.411 136.870 1.00 58.12 ? 41  SER A C   1 
ATOM   57   O O   . SER A 1 13  ? 185.550 158.251 137.873 1.00 58.12 ? 41  SER A O   1 
ATOM   58   C CB  . SER A 1 13  ? 187.614 156.553 135.862 1.00 58.12 ? 41  SER A CB  1 
ATOM   59   O OG  . SER A 1 13  ? 187.805 156.033 137.166 1.00 58.12 ? 41  SER A OG  1 
ATOM   60   N N   . LEU A 1 14  ? 186.988 159.512 136.684 1.00 52.52 ? 42  LEU A N   1 
ATOM   61   C CA  . LEU A 1 14  ? 186.960 160.587 137.669 1.00 52.52 ? 42  LEU A CA  1 
ATOM   62   C C   . LEU A 1 14  ? 185.567 161.192 137.784 1.00 52.52 ? 42  LEU A C   1 
ATOM   63   O O   . LEU A 1 14  ? 185.106 161.498 138.888 1.00 52.52 ? 42  LEU A O   1 
ATOM   64   C CB  . LEU A 1 14  ? 187.984 161.661 137.305 1.00 52.52 ? 42  LEU A CB  1 
ATOM   65   N N   . ILE A 1 15  ? 184.882 161.373 136.652 1.00 52.37 ? 43  ILE A N   1 
ATOM   66   C CA  . ILE A 1 15  ? 183.550 161.972 136.675 1.00 52.37 ? 43  ILE A CA  1 
ATOM   67   C C   . ILE A 1 15  ? 182.581 161.083 137.442 1.00 52.37 ? 43  ILE A C   1 
ATOM   68   O O   . ILE A 1 15  ? 181.813 161.558 138.290 1.00 52.37 ? 43  ILE A O   1 
ATOM   69   C CB  . ILE A 1 15  ? 183.058 162.243 135.242 1.00 52.37 ? 43  ILE A CB  1 
ATOM   70   C CG1 . ILE A 1 15  ? 183.693 163.522 134.697 1.00 52.37 ? 43  ILE A CG1 1 
ATOM   71   C CG2 . ILE A 1 15  ? 181.546 162.347 135.204 1.00 52.37 ? 43  ILE A CG2 1 
ATOM   72   C CD1 . ILE A 1 15  ? 183.238 163.881 133.302 1.00 52.37 ? 43  ILE A CD1 1 
ATOM   73   N N   . VAL A 1 16  ? 182.602 159.779 137.159 1.00 49.96 ? 44  VAL A N   1 
ATOM   74   C CA  . VAL A 1 16  ? 181.702 158.863 137.855 1.00 49.96 ? 44  VAL A CA  1 
ATOM   75   C C   . VAL A 1 16  ? 182.013 158.842 139.344 1.00 49.96 ? 44  VAL A C   1 
ATOM   76   O O   . VAL A 1 16  ? 181.102 158.861 140.184 1.00 49.96 ? 44  VAL A O   1 
ATOM   77   C CB  . VAL A 1 16  ? 181.783 157.453 137.244 1.00 49.96 ? 44  VAL A CB  1 
ATOM   78   C CG1 . VAL A 1 16  ? 180.927 156.490 138.041 1.00 49.96 ? 44  VAL A CG1 1 
ATOM   79   C CG2 . VAL A 1 16  ? 181.337 157.479 135.804 1.00 49.96 ? 44  VAL A CG2 1 
ATOM   80   N N   . LEU A 1 17  ? 183.301 158.800 139.698 1.00 52.21 ? 45  LEU A N   1 
ATOM   81   C CA  . LEU A 1 17  ? 183.669 158.777 141.110 1.00 52.21 ? 45  LEU A CA  1 
ATOM   82   C C   . LEU A 1 17  ? 183.203 160.042 141.818 1.00 52.21 ? 45  LEU A C   1 
ATOM   83   O O   . LEU A 1 17  ? 182.656 159.975 142.926 1.00 52.21 ? 45  LEU A O   1 
ATOM   84   C CB  . LEU A 1 17  ? 185.181 158.603 141.255 1.00 52.21 ? 45  LEU A CB  1 
ATOM   85   N N   . ALA A 1 18  ? 183.396 161.203 141.187 1.00 49.74 ? 46  ALA A N   1 
ATOM   86   C CA  . ALA A 1 18  ? 182.967 162.457 141.794 1.00 49.74 ? 46  ALA A CA  1 
ATOM   87   C C   . ALA A 1 18  ? 181.457 162.495 141.975 1.00 49.74 ? 46  ALA A C   1 
ATOM   88   O O   . ALA A 1 18  ? 180.963 162.893 143.036 1.00 49.74 ? 46  ALA A O   1 
ATOM   89   C CB  . ALA A 1 18  ? 183.435 163.639 140.946 1.00 49.74 ? 46  ALA A CB  1 
ATOM   90   N N   . ILE A 1 19  ? 180.707 162.072 140.954 1.00 46.61 ? 47  ILE A N   1 
ATOM   91   C CA  . ILE A 1 19  ? 179.250 162.093 141.048 1.00 46.61 ? 47  ILE A CA  1 
ATOM   92   C C   . ILE A 1 19  ? 178.779 161.195 142.184 1.00 46.61 ? 47  ILE A C   1 
ATOM   93   O O   . ILE A 1 19  ? 177.980 161.608 143.038 1.00 46.61 ? 47  ILE A O   1 
ATOM   94   C CB  . ILE A 1 19  ? 178.619 161.680 139.707 1.00 46.61 ? 47  ILE A CB  1 
ATOM   95   C CG1 . ILE A 1 19  ? 178.761 162.801 138.681 1.00 46.61 ? 47  ILE A CG1 1 
ATOM   96   C CG2 . ILE A 1 19  ? 177.159 161.329 139.890 1.00 46.61 ? 47  ILE A CG2 1 
ATOM   97   C CD1 . ILE A 1 19  ? 178.278 162.421 137.309 1.00 46.61 ? 47  ILE A CD1 1 
ATOM   98   N N   . VAL A 1 20  ? 179.284 159.960 142.225 1.00 45.08 ? 48  VAL A N   1 
ATOM   99   C CA  . VAL A 1 20  ? 178.840 159.012 143.244 1.00 45.08 ? 48  VAL A CA  1 
ATOM   100  C C   . VAL A 1 20  ? 179.196 159.520 144.634 1.00 45.08 ? 48  VAL A C   1 
ATOM   101  O O   . VAL A 1 20  ? 178.361 159.516 145.548 1.00 45.08 ? 48  VAL A O   1 
ATOM   102  C CB  . VAL A 1 20  ? 179.439 157.619 142.983 1.00 45.08 ? 48  VAL A CB  1 
ATOM   103  C CG1 . VAL A 1 20  ? 179.061 156.670 144.103 1.00 45.08 ? 48  VAL A CG1 1 
ATOM   104  C CG2 . VAL A 1 20  ? 178.956 157.077 141.650 1.00 45.08 ? 48  VAL A CG2 1 
ATOM   105  N N   . PHE A 1 21  ? 180.439 159.979 144.812 1.00 47.77 ? 49  PHE A N   1 
ATOM   106  C CA  . PHE A 1 21  ? 180.879 160.431 146.126 1.00 47.77 ? 49  PHE A CA  1 
ATOM   107  C C   . PHE A 1 21  ? 180.071 161.634 146.594 1.00 47.77 ? 49  PHE A C   1 
ATOM   108  O O   . PHE A 1 21  ? 179.620 161.678 147.743 1.00 47.77 ? 49  PHE A O   1 
ATOM   109  C CB  . PHE A 1 21  ? 182.371 160.762 146.090 1.00 47.77 ? 49  PHE A CB  1 
ATOM   110  N N   . GLY A 1 22  ? 179.860 162.614 145.712 1.00 48.69 ? 50  GLY A N   1 
ATOM   111  C CA  . GLY A 1 22  ? 179.116 163.798 146.108 1.00 48.69 ? 50  GLY A CA  1 
ATOM   112  C C   . GLY A 1 22  ? 177.672 163.495 146.454 1.00 48.69 ? 50  GLY A C   1 
ATOM   113  O O   . GLY A 1 22  ? 177.146 163.991 147.455 1.00 48.69 ? 50  GLY A O   1 
ATOM   114  N N   . ASN A 1 23  ? 177.010 162.674 145.637 1.00 42.83 ? 51  ASN A N   1 
ATOM   115  C CA  . ASN A 1 23  ? 175.615 162.363 145.920 1.00 42.83 ? 51  ASN A CA  1 
ATOM   116  C C   . ASN A 1 23  ? 175.476 161.557 147.206 1.00 42.83 ? 51  ASN A C   1 
ATOM   117  O O   . ASN A 1 23  ? 174.564 161.810 148.005 1.00 42.83 ? 51  ASN A O   1 
ATOM   118  C CB  . ASN A 1 23  ? 174.992 161.628 144.738 1.00 42.83 ? 51  ASN A CB  1 
ATOM   119  C CG  . ASN A 1 23  ? 174.856 162.513 143.517 1.00 42.83 ? 51  ASN A CG  1 
ATOM   120  O OD1 . ASN A 1 23  ? 175.322 162.171 142.432 1.00 42.83 ? 51  ASN A OD1 1 
ATOM   121  N ND2 . ASN A 1 23  ? 174.223 163.666 143.691 1.00 42.83 ? 51  ASN A ND2 1 
ATOM   122  N N   . VAL A 1 24  ? 176.369 160.592 147.435 1.00 48.68 ? 52  VAL A N   1 
ATOM   123  C CA  . VAL A 1 24  ? 176.304 159.828 148.676 1.00 48.68 ? 52  VAL A CA  1 
ATOM   124  C C   . VAL A 1 24  ? 176.590 160.731 149.870 1.00 48.68 ? 52  VAL A C   1 
ATOM   125  O O   . VAL A 1 24  ? 175.970 160.594 150.932 1.00 48.68 ? 52  VAL A O   1 
ATOM   126  C CB  . VAL A 1 24  ? 177.263 158.625 148.618 1.00 48.68 ? 52  VAL A CB  1 
ATOM   127  N N   . LEU A 1 25  ? 177.517 161.679 149.712 1.00 52.32 ? 53  LEU A N   1 
ATOM   128  C CA  . LEU A 1 25  ? 177.796 162.626 150.785 1.00 52.32 ? 53  LEU A CA  1 
ATOM   129  C C   . LEU A 1 25  ? 176.565 163.454 151.120 1.00 52.32 ? 53  LEU A C   1 
ATOM   130  O O   . LEU A 1 25  ? 176.246 163.654 152.297 1.00 52.32 ? 53  LEU A O   1 
ATOM   131  C CB  . LEU A 1 25  ? 178.961 163.532 150.385 1.00 52.32 ? 53  LEU A CB  1 
ATOM   132  C CG  . LEU A 1 25  ? 179.156 164.818 151.187 1.00 52.32 ? 53  LEU A CG  1 
ATOM   133  C CD1 . LEU A 1 25  ? 179.485 164.499 152.635 1.00 52.32 ? 53  LEU A CD1 1 
ATOM   134  C CD2 . LEU A 1 25  ? 180.238 165.681 150.559 1.00 52.32 ? 53  LEU A CD2 1 
ATOM   135  N N   . VAL A 1 26  ? 175.858 163.942 150.098 1.00 51.17 ? 54  VAL A N   1 
ATOM   136  C CA  . VAL A 1 26  ? 174.658 164.741 150.343 1.00 51.17 ? 54  VAL A CA  1 
ATOM   137  C C   . VAL A 1 26  ? 173.588 163.900 151.027 1.00 51.17 ? 54  VAL A C   1 
ATOM   138  O O   . VAL A 1 26  ? 172.930 164.353 151.976 1.00 51.17 ? 54  VAL A O   1 
ATOM   139  C CB  . VAL A 1 26  ? 174.145 165.360 149.030 1.00 51.17 ? 54  VAL A CB  1 
ATOM   140  C CG1 . VAL A 1 26  ? 172.691 165.765 149.165 1.00 51.17 ? 54  VAL A CG1 1 
ATOM   141  C CG2 . VAL A 1 26  ? 174.991 166.558 148.645 1.00 51.17 ? 54  VAL A CG2 1 
ATOM   142  N N   . ILE A 1 27  ? 173.399 162.661 150.564 1.00 53.95 ? 55  ILE A N   1 
ATOM   143  C CA  . ILE A 1 27  ? 172.386 161.794 151.162 1.00 53.95 ? 55  ILE A CA  1 
ATOM   144  C C   . ILE A 1 27  ? 172.699 161.546 152.632 1.00 53.95 ? 55  ILE A C   1 
ATOM   145  O O   . ILE A 1 27  ? 171.818 161.629 153.497 1.00 53.95 ? 55  ILE A O   1 
ATOM   146  C CB  . ILE A 1 27  ? 172.277 160.473 150.380 1.00 53.95 ? 55  ILE A CB  1 
ATOM   147  C CG1 . ILE A 1 27  ? 171.719 160.725 148.980 1.00 53.95 ? 55  ILE A CG1 1 
ATOM   148  C CG2 . ILE A 1 27  ? 171.400 159.485 151.127 1.00 53.95 ? 55  ILE A CG2 1 
ATOM   149  C CD1 . ILE A 1 27  ? 172.017 159.619 147.998 1.00 53.95 ? 55  ILE A CD1 1 
ATOM   150  N N   . THR A 1 28  ? 173.964 161.245 152.938 1.00 59.81 ? 56  THR A N   1 
ATOM   151  C CA  . THR A 1 28  ? 174.350 160.998 154.323 1.00 59.81 ? 56  THR A CA  1 
ATOM   152  C C   . THR A 1 28  ? 174.192 162.253 155.173 1.00 59.81 ? 56  THR A C   1 
ATOM   153  O O   . THR A 1 28  ? 173.720 162.183 156.313 1.00 59.81 ? 56  THR A O   1 
ATOM   154  C CB  . THR A 1 28  ? 175.790 160.484 154.388 1.00 59.81 ? 56  THR A CB  1 
ATOM   155  N N   . ALA A 1 29  ? 174.572 163.413 154.631 1.00 59.21 ? 57  ALA A N   1 
ATOM   156  C CA  . ALA A 1 29  ? 174.462 164.655 155.388 1.00 59.21 ? 57  ALA A CA  1 
ATOM   157  C C   . ALA A 1 29  ? 173.013 164.963 155.728 1.00 59.21 ? 57  ALA A C   1 
ATOM   158  O O   . ALA A 1 29  ? 172.710 165.419 156.836 1.00 59.21 ? 57  ALA A O   1 
ATOM   159  C CB  . ALA A 1 29  ? 175.087 165.808 154.604 1.00 59.21 ? 57  ALA A CB  1 
ATOM   160  N N   . ILE A 1 30  ? 172.100 164.727 154.786 1.00 61.74 ? 58  ILE A N   1 
ATOM   161  C CA  . ILE A 1 30  ? 170.690 164.972 155.069 1.00 61.74 ? 58  ILE A CA  1 
ATOM   162  C C   . ILE A 1 30  ? 170.152 163.946 156.061 1.00 61.74 ? 58  ILE A C   1 
ATOM   163  O O   . ILE A 1 30  ? 169.419 164.293 156.994 1.00 61.74 ? 58  ILE A O   1 
ATOM   164  C CB  . ILE A 1 30  ? 169.875 164.983 153.763 1.00 61.74 ? 58  ILE A CB  1 
ATOM   165  C CG1 . ILE A 1 30  ? 170.195 166.238 152.951 1.00 61.74 ? 58  ILE A CG1 1 
ATOM   166  C CG2 . ILE A 1 30  ? 168.386 164.917 154.061 1.00 61.74 ? 58  ILE A CG2 1 
ATOM   167  C CD1 . ILE A 1 30  ? 169.567 166.250 151.581 1.00 61.74 ? 58  ILE A CD1 1 
ATOM   168  N N   . ALA A 1 31  ? 170.513 162.673 155.889 1.00 65.76 ? 59  ALA A N   1 
ATOM   169  C CA  . ALA A 1 31  ? 169.870 161.618 156.666 1.00 65.76 ? 59  ALA A CA  1 
ATOM   170  C C   . ALA A 1 31  ? 170.380 161.550 158.102 1.00 65.76 ? 59  ALA A C   1 
ATOM   171  O O   . ALA A 1 31  ? 169.606 161.256 159.019 1.00 65.76 ? 59  ALA A O   1 
ATOM   172  C CB  . ALA A 1 31  ? 170.067 160.270 155.974 1.00 65.76 ? 59  ALA A CB  1 
ATOM   173  N N   . LYS A 1 32  ? 171.667 161.817 158.322 1.00 73.28 ? 60  LYS A N   1 
ATOM   174  C CA  . LYS A 1 32  ? 172.279 161.475 159.603 1.00 73.28 ? 60  LYS A CA  1 
ATOM   175  C C   . LYS A 1 32  ? 172.023 162.533 160.671 1.00 73.28 ? 60  LYS A C   1 
ATOM   176  O O   . LYS A 1 32  ? 171.619 162.204 161.792 1.00 73.28 ? 60  LYS A O   1 
ATOM   177  C CB  . LYS A 1 32  ? 173.782 161.258 159.422 1.00 73.28 ? 60  LYS A CB  1 
ATOM   178  C CG  . LYS A 1 32  ? 174.360 160.177 160.319 1.00 73.28 ? 60  LYS A CG  1 
ATOM   179  C CD  . LYS A 1 32  ? 173.615 158.862 160.156 1.00 73.28 ? 60  LYS A CD  1 
ATOM   180  C CE  . LYS A 1 32  ? 174.445 157.693 160.661 1.00 73.28 ? 60  LYS A CE  1 
ATOM   181  N NZ  . LYS A 1 32  ? 173.903 156.383 160.207 1.00 73.28 ? 60  LYS A NZ  1 
ATOM   182  N N   . PHE A 1 33  ? 172.253 163.807 160.348 1.00 82.44 ? 61  PHE A N   1 
ATOM   183  C CA  . PHE A 1 33  ? 172.266 164.848 161.370 1.00 82.44 ? 61  PHE A CA  1 
ATOM   184  C C   . PHE A 1 33  ? 170.899 165.119 161.981 1.00 82.44 ? 61  PHE A C   1 
ATOM   185  O O   . PHE A 1 33  ? 170.835 165.783 163.022 1.00 82.44 ? 61  PHE A O   1 
ATOM   186  C CB  . PHE A 1 33  ? 172.839 166.138 160.793 1.00 82.44 ? 61  PHE A CB  1 
ATOM   187  C CG  . PHE A 1 33  ? 174.329 166.120 160.659 1.00 82.44 ? 61  PHE A CG  1 
ATOM   188  C CD1 . PHE A 1 33  ? 175.069 165.089 161.212 1.00 82.44 ? 61  PHE A CD1 1 
ATOM   189  C CD2 . PHE A 1 33  ? 174.992 167.128 159.989 1.00 82.44 ? 61  PHE A CD2 1 
ATOM   190  C CE1 . PHE A 1 33  ? 176.441 165.063 161.095 1.00 82.44 ? 61  PHE A CE1 1 
ATOM   191  C CE2 . PHE A 1 33  ? 176.362 167.107 159.872 1.00 82.44 ? 61  PHE A CE2 1 
ATOM   192  C CZ  . PHE A 1 33  ? 177.089 166.074 160.423 1.00 82.44 ? 61  PHE A CZ  1 
ATOM   193  N N   . GLU A 1 34  ? 169.817 164.661 161.353 1.00 85.48 ? 62  GLU A N   1 
ATOM   194  C CA  . GLU A 1 34  ? 168.479 164.696 161.938 1.00 85.48 ? 62  GLU A CA  1 
ATOM   195  C C   . GLU A 1 34  ? 167.975 166.118 162.168 1.00 85.48 ? 62  GLU A C   1 
ATOM   196  O O   . GLU A 1 34  ? 166.864 166.313 162.672 1.00 85.48 ? 62  GLU A O   1 
ATOM   197  C CB  . GLU A 1 34  ? 168.450 163.905 163.249 1.00 85.48 ? 62  GLU A CB  1 
ATOM   198  C CG  . GLU A 1 34  ? 167.111 163.255 163.555 1.00 85.48 ? 62  GLU A CG  1 
ATOM   199  C CD  . GLU A 1 34  ? 167.218 162.171 164.607 1.00 85.48 ? 62  GLU A CD  1 
ATOM   200  O OE1 . GLU A 1 34  ? 168.343 161.915 165.084 1.00 85.48 ? 62  GLU A OE1 1 
ATOM   201  O OE2 . GLU A 1 34  ? 166.177 161.575 164.956 1.00 85.48 ? 62  GLU A OE2 1 
ATOM   202  N N   . ARG A 1 35  ? 168.776 167.117 161.802 1.00 84.86 ? 63  ARG A N   1 
ATOM   203  C CA  . ARG A 1 35  ? 168.351 168.509 161.855 1.00 84.86 ? 63  ARG A CA  1 
ATOM   204  C C   . ARG A 1 35  ? 168.039 169.080 160.483 1.00 84.86 ? 63  ARG A C   1 
ATOM   205  O O   . ARG A 1 35  ? 167.227 170.004 160.377 1.00 84.86 ? 63  ARG A O   1 
ATOM   206  C CB  . ARG A 1 35  ? 169.425 169.371 162.526 1.00 84.86 ? 63  ARG A CB  1 
ATOM   207  C CG  . ARG A 1 35  ? 170.818 169.179 161.953 1.00 84.86 ? 63  ARG A CG  1 
ATOM   208  C CD  . ARG A 1 35  ? 171.799 170.166 162.558 1.00 84.86 ? 63  ARG A CD  1 
ATOM   209  N NE  . ARG A 1 35  ? 171.246 171.515 162.611 1.00 84.86 ? 63  ARG A NE  1 
ATOM   210  C CZ  . ARG A 1 35  ? 171.120 172.314 161.558 1.00 84.86 ? 63  ARG A CZ  1 
ATOM   211  N NH1 . ARG A 1 35  ? 171.516 171.906 160.362 1.00 84.86 ? 63  ARG A NH1 1 
ATOM   212  N NH2 . ARG A 1 35  ? 170.605 173.527 161.701 1.00 84.86 ? 63  ARG A NH2 1 
ATOM   213  N N   . LEU A 1 36  ? 168.669 168.553 159.436 1.00 70.26 ? 64  LEU A N   1 
ATOM   214  C CA  . LEU A 1 36  ? 168.373 168.950 158.064 1.00 70.26 ? 64  LEU A CA  1 
ATOM   215  C C   . LEU A 1 36  ? 167.388 167.953 157.456 1.00 70.26 ? 64  LEU A C   1 
ATOM   216  O O   . LEU A 1 36  ? 167.677 167.252 156.488 1.00 70.26 ? 64  LEU A O   1 
ATOM   217  C CB  . LEU A 1 36  ? 169.659 169.036 157.250 1.00 70.26 ? 64  LEU A CB  1 
ATOM   218  C CG  . LEU A 1 36  ? 170.708 170.040 157.726 1.00 70.26 ? 64  LEU A CG  1 
ATOM   219  C CD1 . LEU A 1 36  ? 172.085 169.643 157.236 1.00 70.26 ? 64  LEU A CD1 1 
ATOM   220  C CD2 . LEU A 1 36  ? 170.360 171.438 157.254 1.00 70.26 ? 64  LEU A CD2 1 
ATOM   221  N N   . GLN A 1 37  ? 166.201 167.900 158.054 1.00 70.30 ? 65  GLN A N   1 
ATOM   222  C CA  . GLN A 1 37  ? 165.159 166.970 157.634 1.00 70.30 ? 65  GLN A CA  1 
ATOM   223  C C   . GLN A 1 37  ? 163.875 167.709 157.300 1.00 70.30 ? 65  GLN A C   1 
ATOM   224  O O   . GLN A 1 37  ? 162.770 167.233 157.576 1.00 70.30 ? 65  GLN A O   1 
ATOM   225  C CB  . GLN A 1 37  ? 164.906 165.907 158.699 1.00 70.30 ? 65  GLN A CB  1 
ATOM   226  C CG  . GLN A 1 37  ? 165.867 164.736 158.632 1.00 70.30 ? 65  GLN A CG  1 
ATOM   227  C CD  . GLN A 1 37  ? 165.898 163.937 159.915 1.00 70.30 ? 65  GLN A CD  1 
ATOM   228  O OE1 . GLN A 1 37  ? 165.360 164.362 160.936 1.00 70.30 ? 65  GLN A OE1 1 
ATOM   229  N NE2 . GLN A 1 37  ? 166.534 162.773 159.872 1.00 70.30 ? 65  GLN A NE2 1 
ATOM   230  N N   . THR A 1 38  ? 164.001 168.886 156.699 1.00 56.56 ? 66  THR A N   1 
ATOM   231  C CA  . THR A 1 38  ? 162.836 169.601 156.203 1.00 56.56 ? 66  THR A CA  1 
ATOM   232  C C   . THR A 1 38  ? 162.276 168.881 154.979 1.00 56.56 ? 66  THR A C   1 
ATOM   233  O O   . THR A 1 38  ? 162.971 168.105 154.318 1.00 56.56 ? 66  THR A O   1 
ATOM   234  C CB  . THR A 1 38  ? 163.213 171.043 155.858 1.00 56.56 ? 66  THR A CB  1 
ATOM   235  O OG1 . THR A 1 38  ? 164.017 171.587 156.911 1.00 56.56 ? 66  THR A OG1 1 
ATOM   236  C CG2 . THR A 1 38  ? 161.973 171.911 155.705 1.00 56.56 ? 66  THR A CG2 1 
ATOM   237  N N   . VAL A 1 39  ? 160.997 169.131 154.686 1.00 50.69 ? 67  VAL A N   1 
ATOM   238  C CA  . VAL A 1 39  ? 160.366 168.523 153.516 1.00 50.69 ? 67  VAL A CA  1 
ATOM   239  C C   . VAL A 1 39  ? 161.135 168.885 152.251 1.00 50.69 ? 67  VAL A C   1 
ATOM   240  O O   . VAL A 1 39  ? 161.342 168.044 151.363 1.00 50.69 ? 67  VAL A O   1 
ATOM   241  C CB  . VAL A 1 39  ? 158.889 168.952 153.431 1.00 50.69 ? 67  VAL A CB  1 
ATOM   242  C CG1 . VAL A 1 39  ? 158.230 168.367 152.201 1.00 50.69 ? 67  VAL A CG1 1 
ATOM   243  C CG2 . VAL A 1 39  ? 158.148 168.525 154.682 1.00 50.69 ? 67  VAL A CG2 1 
ATOM   244  N N   . THR A 1 40  ? 161.579 170.140 152.153 1.00 45.19 ? 68  THR A N   1 
ATOM   245  C CA  . THR A 1 40  ? 162.433 170.537 151.039 1.00 45.19 ? 68  THR A CA  1 
ATOM   246  C C   . THR A 1 40  ? 163.690 169.680 150.986 1.00 45.19 ? 68  THR A C   1 
ATOM   247  O O   . THR A 1 40  ? 164.134 169.279 149.904 1.00 45.19 ? 68  THR A O   1 
ATOM   248  C CB  . THR A 1 40  ? 162.796 172.017 151.158 1.00 45.19 ? 68  THR A CB  1 
ATOM   249  O OG1 . THR A 1 40  ? 161.605 172.808 151.087 1.00 45.19 ? 68  THR A OG1 1 
ATOM   250  C CG2 . THR A 1 40  ? 163.736 172.429 150.039 1.00 45.19 ? 68  THR A CG2 1 
ATOM   251  N N   . ASN A 1 41  ? 164.269 169.368 152.147 1.00 50.16 ? 69  ASN A N   1 
ATOM   252  C CA  . ASN A 1 41  ? 165.442 168.503 152.160 1.00 50.16 ? 69  ASN A CA  1 
ATOM   253  C C   . ASN A 1 41  ? 165.097 167.081 151.737 1.00 50.16 ? 69  ASN A C   1 
ATOM   254  O O   . ASN A 1 41  ? 165.938 166.392 151.157 1.00 50.16 ? 69  ASN A O   1 
ATOM   255  C CB  . ASN A 1 41  ? 166.091 168.515 153.540 1.00 50.16 ? 69  ASN A CB  1 
ATOM   256  C CG  . ASN A 1 41  ? 166.714 169.854 153.877 1.00 50.16 ? 69  ASN A CG  1 
ATOM   257  O OD1 . ASN A 1 41  ? 166.296 170.528 154.818 1.00 50.16 ? 69  ASN A OD1 1 
ATOM   258  N ND2 . ASN A 1 41  ? 167.717 170.251 153.104 1.00 50.16 ? 69  ASN A ND2 1 
ATOM   259  N N   . TYR A 1 42  ? 163.871 166.625 151.994 1.00 49.18 ? 70  TYR A N   1 
ATOM   260  C CA  . TYR A 1 42  ? 163.470 165.313 151.495 1.00 49.18 ? 70  TYR A CA  1 
ATOM   261  C C   . TYR A 1 42  ? 163.362 165.311 149.975 1.00 49.18 ? 70  TYR A C   1 
ATOM   262  O O   . TYR A 1 42  ? 163.769 164.345 149.315 1.00 49.18 ? 70  TYR A O   1 
ATOM   263  C CB  . TYR A 1 42  ? 162.150 164.890 152.131 1.00 49.18 ? 70  TYR A CB  1 
ATOM   264  C CG  . TYR A 1 42  ? 162.322 164.232 153.477 1.00 49.18 ? 70  TYR A CG  1 
ATOM   265  C CD1 . TYR A 1 42  ? 161.277 163.548 154.076 1.00 49.18 ? 70  TYR A CD1 1 
ATOM   266  C CD2 . TYR A 1 42  ? 163.536 164.294 154.149 1.00 49.18 ? 70  TYR A CD2 1 
ATOM   267  C CE1 . TYR A 1 42  ? 161.435 162.945 155.304 1.00 49.18 ? 70  TYR A CE1 1 
ATOM   268  C CE2 . TYR A 1 42  ? 163.702 163.695 155.380 1.00 49.18 ? 70  TYR A CE2 1 
ATOM   269  C CZ  . TYR A 1 42  ? 162.648 163.022 155.953 1.00 49.18 ? 70  TYR A CZ  1 
ATOM   270  O OH  . TYR A 1 42  ? 162.807 162.421 157.179 1.00 49.18 ? 70  TYR A OH  1 
ATOM   271  N N   . PHE A 1 43  ? 162.817 166.386 149.401 1.00 38.24 ? 71  PHE A N   1 
ATOM   272  C CA  . PHE A 1 43  ? 162.804 166.511 147.946 1.00 38.24 ? 71  PHE A CA  1 
ATOM   273  C C   . PHE A 1 43  ? 164.221 166.533 147.387 1.00 38.24 ? 71  PHE A C   1 
ATOM   274  O O   . PHE A 1 43  ? 164.504 165.923 146.346 1.00 38.24 ? 71  PHE A O   1 
ATOM   275  C CB  . PHE A 1 43  ? 162.057 167.775 147.542 1.00 38.24 ? 71  PHE A CB  1 
ATOM   276  C CG  . PHE A 1 43  ? 160.582 167.701 147.752 1.00 38.24 ? 71  PHE A CG  1 
ATOM   277  C CD1 . PHE A 1 43  ? 159.832 166.725 147.130 1.00 38.24 ? 71  PHE A CD1 1 
ATOM   278  C CD2 . PHE A 1 43  ? 159.941 168.620 148.560 1.00 38.24 ? 71  PHE A CD2 1 
ATOM   279  C CE1 . PHE A 1 43  ? 158.470 166.661 147.315 1.00 38.24 ? 71  PHE A CE1 1 
ATOM   280  C CE2 . PHE A 1 43  ? 158.579 168.562 148.748 1.00 38.24 ? 71  PHE A CE2 1 
ATOM   281  C CZ  . PHE A 1 43  ? 157.842 167.581 148.126 1.00 38.24 ? 71  PHE A CZ  1 
ATOM   282  N N   . ILE A 1 44  ? 165.122 167.246 148.063 1.00 37.35 ? 72  ILE A N   1 
ATOM   283  C CA  . ILE A 1 44  ? 166.525 167.264 147.663 1.00 37.35 ? 72  ILE A CA  1 
ATOM   284  C C   . ILE A 1 44  ? 167.121 165.865 147.723 1.00 37.35 ? 72  ILE A C   1 
ATOM   285  O O   . ILE A 1 44  ? 167.929 165.484 146.870 1.00 37.35 ? 72  ILE A O   1 
ATOM   286  C CB  . ILE A 1 44  ? 167.310 168.253 148.540 1.00 37.35 ? 72  ILE A CB  1 
ATOM   287  C CG1 . ILE A 1 44  ? 166.792 169.673 148.331 1.00 37.35 ? 72  ILE A CG1 1 
ATOM   288  C CG2 . ILE A 1 44  ? 168.782 168.160 148.258 1.00 37.35 ? 72  ILE A CG2 1 
ATOM   289  C CD1 . ILE A 1 44  ? 167.324 170.661 149.332 1.00 37.35 ? 72  ILE A CD1 1 
ATOM   290  N N   . THR A 1 45  ? 166.752 165.085 148.739 1.00 41.63 ? 73  THR A N   1 
ATOM   291  C CA  . THR A 1 45  ? 167.230 163.709 148.822 1.00 41.63 ? 73  THR A CA  1 
ATOM   292  C C   . THR A 1 45  ? 166.726 162.883 147.647 1.00 41.63 ? 73  THR A C   1 
ATOM   293  O O   . THR A 1 45  ? 167.465 162.062 147.096 1.00 41.63 ? 73  THR A O   1 
ATOM   294  C CB  . THR A 1 45  ? 166.805 163.073 150.145 1.00 41.63 ? 73  THR A CB  1 
ATOM   295  O OG1 . THR A 1 45  ? 167.446 163.756 151.228 1.00 41.63 ? 73  THR A OG1 1 
ATOM   296  C CG2 . THR A 1 45  ? 167.194 161.604 150.185 1.00 41.63 ? 73  THR A CG2 1 
ATOM   297  N N   . SER A 1 46  ? 165.468 163.082 147.253 1.00 33.85 ? 74  SER A N   1 
ATOM   298  C CA  . SER A 1 46  ? 164.957 162.373 146.082 1.00 33.85 ? 74  SER A CA  1 
ATOM   299  C C   . SER A 1 46  ? 165.736 162.748 144.826 1.00 33.85 ? 74  SER A C   1 
ATOM   300  O O   . SER A 1 46  ? 166.077 161.882 144.011 1.00 33.85 ? 74  SER A O   1 
ATOM   301  C CB  . SER A 1 46  ? 163.473 162.662 145.886 1.00 33.85 ? 74  SER A CB  1 
ATOM   302  O OG  . SER A 1 46  ? 163.056 162.244 144.598 1.00 33.85 ? 74  SER A OG  1 
ATOM   303  N N   . LEU A 1 47  ? 166.025 164.038 144.654 1.00 31.07 ? 75  LEU A N   1 
ATOM   304  C CA  . LEU A 1 47  ? 166.790 164.477 143.489 1.00 31.07 ? 75  LEU A CA  1 
ATOM   305  C C   . LEU A 1 47  ? 168.203 163.903 143.504 1.00 31.07 ? 75  LEU A C   1 
ATOM   306  O O   . LEU A 1 47  ? 168.734 163.501 142.459 1.00 31.07 ? 75  LEU A O   1 
ATOM   307  C CB  . LEU A 1 47  ? 166.827 166.002 143.439 1.00 31.07 ? 75  LEU A CB  1 
ATOM   308  C CG  . LEU A 1 47  ? 167.353 166.682 142.181 1.00 31.07 ? 75  LEU A CG  1 
ATOM   309  C CD1 . LEU A 1 47  ? 166.596 167.965 141.950 1.00 31.07 ? 75  LEU A CD1 1 
ATOM   310  C CD2 . LEU A 1 47  ? 168.824 166.972 142.326 1.00 31.07 ? 75  LEU A CD2 1 
ATOM   311  N N   . ALA A 1 48  ? 168.836 163.877 144.678 1.00 34.20 ? 76  ALA A N   1 
ATOM   312  C CA  . ALA A 1 48  ? 170.174 163.310 144.795 1.00 34.20 ? 76  ALA A CA  1 
ATOM   313  C C   . ALA A 1 48  ? 170.166 161.815 144.507 1.00 34.20 ? 76  ALA A C   1 
ATOM   314  O O   . ALA A 1 48  ? 171.088 161.296 143.874 1.00 34.20 ? 76  ALA A O   1 
ATOM   315  C CB  . ALA A 1 48  ? 170.746 163.588 146.183 1.00 34.20 ? 76  ALA A CB  1 
ATOM   316  N N   . CYS A 1 49  ? 169.134 161.105 144.959 1.00 33.06 ? 77  CYS A N   1 
ATOM   317  C CA  . CYS A 1 49  ? 169.012 159.695 144.613 1.00 33.06 ? 77  CYS A CA  1 
ATOM   318  C C   . CYS A 1 49  ? 168.864 159.517 143.108 1.00 33.06 ? 77  CYS A C   1 
ATOM   319  O O   . CYS A 1 49  ? 169.480 158.623 142.518 1.00 33.06 ? 77  CYS A O   1 
ATOM   320  C CB  . CYS A 1 49  ? 167.827 159.075 145.350 1.00 33.06 ? 77  CYS A CB  1 
ATOM   321  S SG  . CYS A 1 49  ? 167.829 157.273 145.399 1.00 33.06 ? 77  CYS A SG  1 
ATOM   322  N N   . ALA A 1 50  ? 168.064 160.373 142.468 1.00 27.58 ? 78  ALA A N   1 
ATOM   323  C CA  . ALA A 1 50  ? 167.865 160.271 141.025 1.00 27.58 ? 78  ALA A CA  1 
ATOM   324  C C   . ALA A 1 50  ? 169.173 160.456 140.270 1.00 27.58 ? 78  ALA A C   1 
ATOM   325  O O   . ALA A 1 50  ? 169.532 159.641 139.408 1.00 27.58 ? 78  ALA A O   1 
ATOM   326  C CB  . ALA A 1 50  ? 166.840 161.304 140.564 1.00 27.58 ? 78  ALA A CB  1 
ATOM   327  N N   . ASP A 1 51  ? 169.904 161.524 140.573 1.00 29.97 ? 79  ASP A N   1 
ATOM   328  C CA  . ASP A 1 51  ? 171.118 161.745 139.802 1.00 29.97 ? 79  ASP A CA  1 
ATOM   329  C C   . ASP A 1 51  ? 172.236 160.788 140.200 1.00 29.97 ? 79  ASP A C   1 
ATOM   330  O O   . ASP A 1 51  ? 173.086 160.484 139.361 1.00 29.97 ? 79  ASP A O   1 
ATOM   331  C CB  . ASP A 1 51  ? 171.567 163.214 139.874 1.00 29.97 ? 79  ASP A CB  1 
ATOM   332  C CG  . ASP A 1 51  ? 172.270 163.579 141.165 1.00 29.97 ? 79  ASP A CG  1 
ATOM   333  O OD1 . ASP A 1 51  ? 172.239 162.800 142.130 1.00 29.97 ? 79  ASP A OD1 1 
ATOM   334  O OD2 . ASP A 1 51  ? 172.870 164.674 141.209 1.00 29.97 ? 79  ASP A OD2 1 
ATOM   335  N N   . LEU A 1 52  ? 172.233 160.265 141.431 1.00 32.90 ? 80  LEU A N   1 
ATOM   336  C CA  . LEU A 1 52  ? 173.170 159.198 141.775 1.00 32.90 ? 80  LEU A CA  1 
ATOM   337  C C   . LEU A 1 52  ? 172.889 157.936 140.973 1.00 32.90 ? 80  LEU A C   1 
ATOM   338  O O   . LEU A 1 52  ? 173.819 157.289 140.478 1.00 32.90 ? 80  LEU A O   1 
ATOM   339  C CB  . LEU A 1 52  ? 173.099 158.889 143.268 1.00 32.90 ? 80  LEU A CB  1 
ATOM   340  C CG  . LEU A 1 52  ? 173.792 157.590 143.685 1.00 32.90 ? 80  LEU A CG  1 
ATOM   341  C CD1 . LEU A 1 52  ? 175.297 157.784 143.726 1.00 32.90 ? 80  LEU A CD1 1 
ATOM   342  C CD2 . LEU A 1 52  ? 173.271 157.093 145.021 1.00 32.90 ? 80  LEU A CD2 1 
ATOM   343  N N   . VAL A 1 53  ? 171.614 157.563 140.845 1.00 25.83 ? 81  VAL A N   1 
ATOM   344  C CA  . VAL A 1 53  ? 171.261 156.405 140.032 1.00 25.83 ? 81  VAL A CA  1 
ATOM   345  C C   . VAL A 1 53  ? 171.732 156.610 138.602 1.00 25.83 ? 81  VAL A C   1 
ATOM   346  O O   . VAL A 1 53  ? 172.370 155.731 138.009 1.00 25.83 ? 81  VAL A O   1 
ATOM   347  C CB  . VAL A 1 53  ? 169.746 156.141 140.091 1.00 25.83 ? 81  VAL A CB  1 
ATOM   348  C CG1 . VAL A 1 53  ? 169.307 155.315 138.900 1.00 25.83 ? 81  VAL A CG1 1 
ATOM   349  C CG2 . VAL A 1 53  ? 169.381 155.439 141.383 1.00 25.83 ? 81  VAL A CG2 1 
ATOM   350  N N   . MET A 1 54  ? 171.445 157.785 138.029 1.00 29.59 ? 82  MET A N   1 
ATOM   351  C CA  . MET A 1 54  ? 171.834 158.003 136.638 1.00 29.59 ? 82  MET A CA  1 
ATOM   352  C C   . MET A 1 54  ? 173.345 157.963 136.488 1.00 29.59 ? 82  MET A C   1 
ATOM   353  O O   . MET A 1 54  ? 173.864 157.272 135.609 1.00 29.59 ? 82  MET A O   1 
ATOM   354  C CB  . MET A 1 54  ? 171.280 159.315 136.085 1.00 29.59 ? 82  MET A CB  1 
ATOM   355  C CG  . MET A 1 54  ? 172.120 159.879 134.946 1.00 29.59 ? 82  MET A CG  1 
ATOM   356  S SD  . MET A 1 54  ? 171.425 161.342 134.161 1.00 29.59 ? 82  MET A SD  1 
ATOM   357  C CE  . MET A 1 54  ? 171.662 162.571 135.427 1.00 29.59 ? 82  MET A CE  1 
ATOM   358  N N   . GLY A 1 55  ? 174.069 158.659 137.362 1.00 29.50 ? 83  GLY A N   1 
ATOM   359  C CA  . GLY A 1 55  ? 175.513 158.588 137.347 1.00 29.50 ? 83  GLY A CA  1 
ATOM   360  C C   . GLY A 1 55  ? 175.988 157.153 137.355 1.00 29.50 ? 83  GLY A C   1 
ATOM   361  O O   . GLY A 1 55  ? 176.455 156.651 136.326 1.00 29.50 ? 83  GLY A O   1 
ATOM   362  N N   . LEU A 1 56  ? 175.756 156.466 138.476 1.00 30.41 ? 84  LEU A N   1 
ATOM   363  C CA  . LEU A 1 56  ? 176.304 155.131 138.700 1.00 30.41 ? 84  LEU A CA  1 
ATOM   364  C C   . LEU A 1 56  ? 175.955 154.163 137.575 1.00 30.41 ? 84  LEU A C   1 
ATOM   365  O O   . LEU A 1 56  ? 176.829 153.459 137.059 1.00 30.41 ? 84  LEU A O   1 
ATOM   366  C CB  . LEU A 1 56  ? 175.794 154.596 140.039 1.00 30.41 ? 84  LEU A CB  1 
ATOM   367  C CG  . LEU A 1 56  ? 176.372 153.294 140.585 1.00 30.41 ? 84  LEU A CG  1 
ATOM   368  C CD1 . LEU A 1 56  ? 177.841 153.462 140.908 1.00 30.41 ? 84  LEU A CD1 1 
ATOM   369  C CD2 . LEU A 1 56  ? 175.595 152.855 141.814 1.00 30.41 ? 84  LEU A CD2 1 
ATOM   370  N N   . ALA A 1 57  ? 174.682 154.109 137.174 1.00 30.34 ? 85  ALA A N   1 
ATOM   371  C CA  . ALA A 1 57  ? 174.275 153.085 136.219 1.00 30.34 ? 85  ALA A CA  1 
ATOM   372  C C   . ALA A 1 57  ? 174.581 153.489 134.781 1.00 30.34 ? 85  ALA A C   1 
ATOM   373  O O   . ALA A 1 57  ? 175.143 152.697 134.019 1.00 30.34 ? 85  ALA A O   1 
ATOM   374  C CB  . ALA A 1 57  ? 172.789 152.776 136.383 1.00 30.34 ? 85  ALA A CB  1 
ATOM   375  N N   . VAL A 1 58  ? 174.213 154.710 134.382 1.00 31.63 ? 86  VAL A N   1 
ATOM   376  C CA  . VAL A 1 58  ? 174.294 155.094 132.979 1.00 31.63 ? 86  VAL A CA  1 
ATOM   377  C C   . VAL A 1 58  ? 175.709 155.518 132.604 1.00 31.63 ? 86  VAL A C   1 
ATOM   378  O O   . VAL A 1 58  ? 176.276 155.018 131.627 1.00 31.63 ? 86  VAL A O   1 
ATOM   379  C CB  . VAL A 1 58  ? 173.283 156.213 132.681 1.00 31.63 ? 86  VAL A CB  1 
ATOM   380  C CG1 . VAL A 1 58  ? 173.437 156.685 131.253 1.00 31.63 ? 86  VAL A CG1 1 
ATOM   381  C CG2 . VAL A 1 58  ? 171.871 155.732 132.946 1.00 31.63 ? 86  VAL A CG2 1 
ATOM   382  N N   . VAL A 1 59  ? 176.296 156.460 133.357 1.00 31.39 ? 87  VAL A N   1 
ATOM   383  C CA  . VAL A 1 59  ? 177.496 157.150 132.874 1.00 31.39 ? 87  VAL A CA  1 
ATOM   384  C C   . VAL A 1 59  ? 178.648 156.198 132.582 1.00 31.39 ? 87  VAL A C   1 
ATOM   385  O O   . VAL A 1 59  ? 179.267 156.327 131.508 1.00 31.39 ? 87  VAL A O   1 
ATOM   386  C CB  . VAL A 1 59  ? 177.892 158.265 133.857 1.00 31.39 ? 87  VAL A CB  1 
ATOM   387  C CG1 . VAL A 1 59  ? 179.110 158.996 133.348 1.00 31.39 ? 87  VAL A CG1 1 
ATOM   388  C CG2 . VAL A 1 59  ? 176.750 159.234 134.039 1.00 31.39 ? 87  VAL A CG2 1 
ATOM   389  N N   . PRO A 1 60  ? 179.011 155.249 133.458 1.00 37.83 ? 88  PRO A N   1 
ATOM   390  C CA  . PRO A 1 60  ? 180.121 154.344 133.118 1.00 37.83 ? 88  PRO A CA  1 
ATOM   391  C C   . PRO A 1 60  ? 179.879 153.539 131.857 1.00 37.83 ? 88  PRO A C   1 
ATOM   392  O O   . PRO A 1 60  ? 180.808 153.317 131.072 1.00 37.83 ? 88  PRO A O   1 
ATOM   393  C CB  . PRO A 1 60  ? 180.219 153.432 134.348 1.00 37.83 ? 88  PRO A CB  1 
ATOM   394  C CG  . PRO A 1 60  ? 179.577 154.186 135.440 1.00 37.83 ? 88  PRO A CG  1 
ATOM   395  C CD  . PRO A 1 60  ? 178.477 154.954 134.801 1.00 37.83 ? 88  PRO A CD  1 
ATOM   396  N N   . PHE A 1 61  ? 178.642 153.104 131.630 1.00 39.54 ? 89  PHE A N   1 
ATOM   397  C CA  . PHE A 1 61  ? 178.374 152.222 130.501 1.00 39.54 ? 89  PHE A CA  1 
ATOM   398  C C   . PHE A 1 61  ? 178.325 152.994 129.190 1.00 39.54 ? 89  PHE A C   1 
ATOM   399  O O   . PHE A 1 61  ? 178.797 152.501 128.160 1.00 39.54 ? 89  PHE A O   1 
ATOM   400  C CB  . PHE A 1 61  ? 177.084 151.447 130.748 1.00 39.54 ? 89  PHE A CB  1 
ATOM   401  C CG  . PHE A 1 61  ? 177.212 150.394 131.815 1.00 39.54 ? 89  PHE A CG  1 
ATOM   402  C CD1 . PHE A 1 61  ? 176.372 149.299 131.825 1.00 39.54 ? 89  PHE A CD1 1 
ATOM   403  C CD2 . PHE A 1 61  ? 178.183 150.491 132.801 1.00 39.54 ? 89  PHE A CD2 1 
ATOM   404  C CE1 . PHE A 1 61  ? 176.489 148.334 132.798 1.00 39.54 ? 89  PHE A CE1 1 
ATOM   405  C CE2 . PHE A 1 61  ? 178.301 149.524 133.777 1.00 39.54 ? 89  PHE A CE2 1 
ATOM   406  C CZ  . PHE A 1 61  ? 177.454 148.448 133.776 1.00 39.54 ? 89  PHE A CZ  1 
ATOM   407  N N   . GLY A 1 62  ? 177.777 154.208 129.210 1.00 39.25 ? 90  GLY A N   1 
ATOM   408  C CA  . GLY A 1 62  ? 177.895 155.072 128.047 1.00 39.25 ? 90  GLY A CA  1 
ATOM   409  C C   . GLY A 1 62  ? 179.337 155.440 127.757 1.00 39.25 ? 90  GLY A C   1 
ATOM   410  O O   . GLY A 1 62  ? 179.743 155.561 126.597 1.00 39.25 ? 90  GLY A O   1 
ATOM   411  N N   . ALA A 1 63  ? 180.136 155.609 128.812 1.00 47.74 ? 91  ALA A N   1 
ATOM   412  C CA  . ALA A 1 63  ? 181.567 155.821 128.626 1.00 47.74 ? 91  ALA A CA  1 
ATOM   413  C C   . ALA A 1 63  ? 182.222 154.622 127.950 1.00 47.74 ? 91  ALA A C   1 
ATOM   414  O O   . ALA A 1 63  ? 183.040 154.782 127.037 1.00 47.74 ? 91  ALA A O   1 
ATOM   415  C CB  . ALA A 1 63  ? 182.231 156.103 129.973 1.00 47.74 ? 91  ALA A CB  1 
ATOM   416  N N   . ALA A 1 64  ? 181.873 153.410 128.385 1.00 54.59 ? 92  ALA A N   1 
ATOM   417  C CA  . ALA A 1 64  ? 182.418 152.214 127.749 1.00 54.59 ? 92  ALA A CA  1 
ATOM   418  C C   . ALA A 1 64  ? 181.987 152.127 126.292 1.00 54.59 ? 92  ALA A C   1 
ATOM   419  O O   . ALA A 1 64  ? 182.769 151.719 125.427 1.00 54.59 ? 92  ALA A O   1 
ATOM   420  C CB  . ALA A 1 64  ? 181.984 150.965 128.512 1.00 54.59 ? 92  ALA A CB  1 
ATOM   421  N N   . HIS A 1 65  ? 180.741 152.504 126.003 1.00 55.03 ? 93  HIS A N   1 
ATOM   422  C CA  . HIS A 1 65  ? 180.271 152.510 124.622 1.00 55.03 ? 93  HIS A CA  1 
ATOM   423  C C   . HIS A 1 65  ? 181.076 153.480 123.766 1.00 55.03 ? 93  HIS A C   1 
ATOM   424  O O   . HIS A 1 65  ? 181.457 153.152 122.636 1.00 55.03 ? 93  HIS A O   1 
ATOM   425  C CB  . HIS A 1 65  ? 178.789 152.876 124.572 1.00 55.03 ? 93  HIS A CB  1 
ATOM   426  C CG  . HIS A 1 65  ? 178.232 152.948 123.184 1.00 55.03 ? 93  HIS A CG  1 
ATOM   427  N ND1 . HIS A 1 65  ? 178.383 151.930 122.268 1.00 55.03 ? 93  HIS A ND1 1 
ATOM   428  C CD2 . HIS A 1 65  ? 177.530 153.918 122.555 1.00 55.03 ? 93  HIS A CD2 1 
ATOM   429  C CE1 . HIS A 1 65  ? 177.792 152.267 121.136 1.00 55.03 ? 93  HIS A CE1 1 
ATOM   430  N NE2 . HIS A 1 65  ? 177.268 153.470 121.283 1.00 55.03 ? 93  HIS A NE2 1 
ATOM   431  N N   . ILE A 1 66  ? 181.342 154.682 124.281 1.00 54.09 ? 94  ILE A N   1 
ATOM   432  C CA  . ILE A 1 66  ? 182.067 155.654 123.467 1.00 54.09 ? 94  ILE A CA  1 
ATOM   433  C C   . ILE A 1 66  ? 183.546 155.295 123.382 1.00 54.09 ? 94  ILE A C   1 
ATOM   434  O O   . ILE A 1 66  ? 184.239 155.710 122.445 1.00 54.09 ? 94  ILE A O   1 
ATOM   435  C CB  . ILE A 1 66  ? 181.861 157.085 124.000 1.00 54.09 ? 94  ILE A CB  1 
ATOM   436  C CG1 . ILE A 1 66  ? 182.350 158.107 122.974 1.00 54.09 ? 94  ILE A CG1 1 
ATOM   437  C CG2 . ILE A 1 66  ? 182.610 157.293 125.296 1.00 54.09 ? 94  ILE A CG2 1 
ATOM   438  C CD1 . ILE A 1 66  ? 181.543 158.117 121.700 1.00 54.09 ? 94  ILE A CD1 1 
ATOM   439  N N   . LEU A 1 67  ? 184.054 154.514 124.336 1.00 63.07 ? 95  LEU A N   1 
ATOM   440  C CA  . LEU A 1 67  ? 185.477 154.186 124.341 1.00 63.07 ? 95  LEU A CA  1 
ATOM   441  C C   . LEU A 1 67  ? 185.780 152.966 123.477 1.00 63.07 ? 95  LEU A C   1 
ATOM   442  O O   . LEU A 1 67  ? 186.576 153.042 122.535 1.00 63.07 ? 95  LEU A O   1 
ATOM   443  C CB  . LEU A 1 67  ? 185.956 153.955 125.775 1.00 63.07 ? 95  LEU A CB  1 
ATOM   444  C CG  . LEU A 1 67  ? 186.157 155.209 126.624 1.00 63.07 ? 95  LEU A CG  1 
ATOM   445  C CD1 . LEU A 1 67  ? 186.253 154.846 128.098 1.00 63.07 ? 95  LEU A CD1 1 
ATOM   446  C CD2 . LEU A 1 67  ? 187.388 155.977 126.170 1.00 63.07 ? 95  LEU A CD2 1 
ATOM   447  N N   . MET A 1 68  ? 185.157 151.829 123.788 1.00 70.77 ? 96  MET A N   1 
ATOM   448  C CA  . MET A 1 68  ? 185.485 150.588 123.097 1.00 70.77 ? 96  MET A CA  1 
ATOM   449  C C   . MET A 1 68  ? 185.085 150.604 121.629 1.00 70.77 ? 96  MET A C   1 
ATOM   450  O O   . MET A 1 68  ? 185.615 149.802 120.854 1.00 70.77 ? 96  MET A O   1 
ATOM   451  C CB  . MET A 1 68  ? 184.814 149.404 123.793 1.00 70.77 ? 96  MET A CB  1 
ATOM   452  C CG  . MET A 1 68  ? 185.643 148.785 124.904 1.00 70.77 ? 96  MET A CG  1 
ATOM   453  S SD  . MET A 1 68  ? 184.637 147.885 126.098 1.00 70.77 ? 96  MET A SD  1 
ATOM   454  C CE  . MET A 1 68  ? 185.712 147.905 127.528 1.00 70.77 ? 96  MET A CE  1 
ATOM   455  N N   . LYS A 1 69  ? 184.160 151.480 121.237 1.00 73.23 ? 97  LYS A N   1 
ATOM   456  C CA  . LYS A 1 69  ? 183.579 151.584 119.900 1.00 73.23 ? 97  LYS A CA  1 
ATOM   457  C C   . LYS A 1 69  ? 182.712 150.383 119.551 1.00 73.23 ? 97  LYS A C   1 
ATOM   458  O O   . LYS A 1 69  ? 182.080 150.379 118.488 1.00 73.23 ? 97  LYS A O   1 
ATOM   459  C CB  . LYS A 1 69  ? 184.638 151.769 118.804 1.00 73.23 ? 97  LYS A CB  1 
ATOM   460  C CG  . LYS A 1 69  ? 185.059 153.207 118.586 1.00 73.23 ? 97  LYS A CG  1 
ATOM   461  C CD  . LYS A 1 69  ? 186.011 153.327 117.411 1.00 73.23 ? 97  LYS A CD  1 
ATOM   462  C CE  . LYS A 1 69  ? 185.708 154.569 116.593 1.00 73.23 ? 97  LYS A CE  1 
ATOM   463  N NZ  . LYS A 1 69  ? 185.427 155.743 117.463 1.00 73.23 ? 97  LYS A NZ  1 
ATOM   464  N N   . MET A 1 70  ? 182.656 149.367 120.407 1.00 73.17 ? 98  MET A N   1 
ATOM   465  C CA  . MET A 1 70  ? 181.760 148.234 120.239 1.00 73.17 ? 98  MET A CA  1 
ATOM   466  C C   . MET A 1 70  ? 181.089 147.973 121.576 1.00 73.17 ? 98  MET A C   1 
ATOM   467  O O   . MET A 1 70  ? 181.742 148.023 122.622 1.00 73.17 ? 98  MET A O   1 
ATOM   468  C CB  . MET A 1 70  ? 182.512 146.989 119.744 1.00 73.17 ? 98  MET A CB  1 
ATOM   469  C CG  . MET A 1 70  ? 183.531 146.423 120.724 1.00 73.17 ? 98  MET A CG  1 
ATOM   470  S SD  . MET A 1 70  ? 184.425 144.995 120.081 1.00 73.17 ? 98  MET A SD  1 
ATOM   471  C CE  . MET A 1 70  ? 185.515 144.627 121.454 1.00 73.17 ? 98  MET A CE  1 
ATOM   472  N N   . TRP A 1 71  ? 179.788 147.718 121.544 1.00 67.14 ? 99  TRP A N   1 
ATOM   473  C CA  . TRP A 1 71  ? 178.981 147.584 122.752 1.00 67.14 ? 99  TRP A CA  1 
ATOM   474  C C   . TRP A 1 71  ? 178.577 146.118 122.857 1.00 67.14 ? 99  TRP A C   1 
ATOM   475  O O   . TRP A 1 71  ? 177.603 145.685 122.235 1.00 67.14 ? 99  TRP A O   1 
ATOM   476  C CB  . TRP A 1 71  ? 177.772 148.511 122.695 1.00 67.14 ? 99  TRP A CB  1 
ATOM   477  C CG  . TRP A 1 71  ? 177.223 148.883 124.032 1.00 67.14 ? 99  TRP A CG  1 
ATOM   478  C CD1 . TRP A 1 71  ? 177.760 149.768 124.919 1.00 67.14 ? 99  TRP A CD1 1 
ATOM   479  C CD2 . TRP A 1 71  ? 176.023 148.393 124.633 1.00 67.14 ? 99  TRP A CD2 1 
ATOM   480  N NE1 . TRP A 1 71  ? 176.970 149.859 126.037 1.00 67.14 ? 99  TRP A NE1 1 
ATOM   481  C CE2 . TRP A 1 71  ? 175.897 149.023 125.887 1.00 67.14 ? 99  TRP A CE2 1 
ATOM   482  C CE3 . TRP A 1 71  ? 175.046 147.481 124.236 1.00 67.14 ? 99  TRP A CE3 1 
ATOM   483  C CZ2 . TRP A 1 71  ? 174.837 148.768 126.743 1.00 67.14 ? 99  TRP A CZ2 1 
ATOM   484  C CZ3 . TRP A 1 71  ? 173.998 147.232 125.084 1.00 67.14 ? 99  TRP A CZ3 1 
ATOM   485  C CH2 . TRP A 1 71  ? 173.900 147.871 126.325 1.00 67.14 ? 99  TRP A CH2 1 
ATOM   486  N N   . THR A 1 72  ? 179.328 145.362 123.653 1.00 68.12 ? 100 THR A N   1 
ATOM   487  C CA  . THR A 1 72  ? 179.217 143.906 123.716 1.00 68.12 ? 100 THR A CA  1 
ATOM   488  C C   . THR A 1 72  ? 178.380 143.446 124.901 1.00 68.12 ? 100 THR A C   1 
ATOM   489  O O   . THR A 1 72  ? 178.659 142.410 125.510 1.00 68.12 ? 100 THR A O   1 
ATOM   490  C CB  . THR A 1 72  ? 180.608 143.279 123.764 1.00 68.12 ? 100 THR A CB  1 
ATOM   491  O OG1 . THR A 1 72  ? 180.495 141.855 123.886 1.00 68.12 ? 100 THR A OG1 1 
ATOM   492  C CG2 . THR A 1 72  ? 181.409 143.834 124.938 1.00 68.12 ? 100 THR A CG2 1 
ATOM   493  N N   . PHE A 1 73  ? 177.337 144.197 125.248 1.00 59.82 ? 101 PHE A N   1 
ATOM   494  C CA  . PHE A 1 73  ? 176.581 143.919 126.461 1.00 59.82 ? 101 PHE A CA  1 
ATOM   495  C C   . PHE A 1 73  ? 175.233 143.259 126.203 1.00 59.82 ? 101 PHE A C   1 
ATOM   496  O O   . PHE A 1 73  ? 174.738 142.537 127.074 1.00 59.82 ? 101 PHE A O   1 
ATOM   497  C CB  . PHE A 1 73  ? 176.374 145.211 127.259 1.00 59.82 ? 101 PHE A CB  1 
ATOM   498  C CG  . PHE A 1 73  ? 177.613 145.699 127.974 1.00 59.82 ? 101 PHE A CG  1 
ATOM   499  C CD1 . PHE A 1 73  ? 177.503 146.488 129.104 1.00 59.82 ? 101 PHE A CD1 1 
ATOM   500  C CD2 . PHE A 1 73  ? 178.878 145.378 127.515 1.00 59.82 ? 101 PHE A CD2 1 
ATOM   501  C CE1 . PHE A 1 73  ? 178.626 146.940 129.762 1.00 59.82 ? 101 PHE A CE1 1 
ATOM   502  C CE2 . PHE A 1 73  ? 180.003 145.830 128.170 1.00 59.82 ? 101 PHE A CE2 1 
ATOM   503  C CZ  . PHE A 1 73  ? 179.876 146.612 129.295 1.00 59.82 ? 101 PHE A CZ  1 
ATOM   504  N N   . GLY A 1 74  ? 174.623 143.483 125.040 1.00 60.61 ? 102 GLY A N   1 
ATOM   505  C CA  . GLY A 1 74  ? 173.398 142.785 124.692 1.00 60.61 ? 102 GLY A CA  1 
ATOM   506  C C   . GLY A 1 74  ? 172.228 143.669 124.303 1.00 60.61 ? 102 GLY A C   1 
ATOM   507  O O   . GLY A 1 74  ? 172.153 144.830 124.714 1.00 60.61 ? 102 GLY A O   1 
ATOM   508  N N   . ASN A 1 75  ? 171.305 143.126 123.505 1.00 55.77 ? 103 ASN A N   1 
ATOM   509  C CA  . ASN A 1 75  ? 170.130 143.888 123.087 1.00 55.77 ? 103 ASN A CA  1 
ATOM   510  C C   . ASN A 1 75  ? 169.220 144.200 124.271 1.00 55.77 ? 103 ASN A C   1 
ATOM   511  O O   . ASN A 1 75  ? 168.778 145.347 124.448 1.00 55.77 ? 103 ASN A O   1 
ATOM   512  C CB  . ASN A 1 75  ? 169.374 143.114 122.007 1.00 55.77 ? 103 ASN A CB  1 
ATOM   513  C CG  . ASN A 1 75  ? 167.989 143.667 121.749 1.00 55.77 ? 103 ASN A CG  1 
ATOM   514  O OD1 . ASN A 1 75  ? 167.026 143.302 122.422 1.00 55.77 ? 103 ASN A OD1 1 
ATOM   515  N ND2 . ASN A 1 75  ? 167.880 144.553 120.768 1.00 55.77 ? 103 ASN A ND2 1 
ATOM   516  N N   . PHE A 1 76  ? 168.928 143.188 125.093 1.00 52.90 ? 104 PHE A N   1 
ATOM   517  C CA  . PHE A 1 76  ? 168.154 143.426 126.304 1.00 52.90 ? 104 PHE A CA  1 
ATOM   518  C C   . PHE A 1 76  ? 168.817 144.476 127.175 1.00 52.90 ? 104 PHE A C   1 
ATOM   519  O O   . PHE A 1 76  ? 168.147 145.370 127.714 1.00 52.90 ? 104 PHE A O   1 
ATOM   520  C CB  . PHE A 1 76  ? 167.993 142.131 127.095 1.00 52.90 ? 104 PHE A CB  1 
ATOM   521  C CG  . PHE A 1 76  ? 167.796 142.351 128.567 1.00 52.90 ? 104 PHE A CG  1 
ATOM   522  C CD1 . PHE A 1 76  ? 166.564 142.724 129.072 1.00 52.90 ? 104 PHE A CD1 1 
ATOM   523  C CD2 . PHE A 1 76  ? 168.856 142.196 129.447 1.00 52.90 ? 104 PHE A CD2 1 
ATOM   524  C CE1 . PHE A 1 76  ? 166.392 142.931 130.426 1.00 52.90 ? 104 PHE A CE1 1 
ATOM   525  C CE2 . PHE A 1 76  ? 168.689 142.403 130.801 1.00 52.90 ? 104 PHE A CE2 1 
ATOM   526  C CZ  . PHE A 1 76  ? 167.456 142.770 131.290 1.00 52.90 ? 104 PHE A CZ  1 
ATOM   527  N N   . TRP A 1 77  ? 170.132 144.374 127.337 1.00 61.42 ? 105 TRP A N   1 
ATOM   528  C CA  . TRP A 1 77  ? 170.810 145.275 128.250 1.00 61.42 ? 105 TRP A CA  1 
ATOM   529  C C   . TRP A 1 77  ? 170.767 146.689 127.686 1.00 61.42 ? 105 TRP A C   1 
ATOM   530  O O   . TRP A 1 77  ? 170.688 147.668 128.434 1.00 61.42 ? 105 TRP A O   1 
ATOM   531  C CB  . TRP A 1 77  ? 172.244 144.800 128.468 1.00 61.42 ? 105 TRP A CB  1 
ATOM   532  C CG  . TRP A 1 77  ? 172.984 145.583 129.471 1.00 61.42 ? 105 TRP A CG  1 
ATOM   533  C CD1 . TRP A 1 77  ? 173.921 146.554 129.266 1.00 61.42 ? 105 TRP A CD1 1 
ATOM   534  C CD2 . TRP A 1 77  ? 172.902 145.393 130.885 1.00 61.42 ? 105 TRP A CD2 1 
ATOM   535  N NE1 . TRP A 1 77  ? 174.389 147.016 130.477 1.00 61.42 ? 105 TRP A NE1 1 
ATOM   536  C CE2 . TRP A 1 77  ? 173.779 146.310 131.484 1.00 61.42 ? 105 TRP A CE2 1 
ATOM   537  C CE3 . TRP A 1 77  ? 172.152 144.543 131.704 1.00 61.42 ? 105 TRP A CE3 1 
ATOM   538  C CZ2 . TRP A 1 77  ? 173.925 146.400 132.869 1.00 61.42 ? 105 TRP A CZ2 1 
ATOM   539  C CZ3 . TRP A 1 77  ? 172.299 144.634 133.074 1.00 61.42 ? 105 TRP A CZ3 1 
ATOM   540  C CH2 . TRP A 1 77  ? 173.179 145.556 133.644 1.00 61.42 ? 105 TRP A CH2 1 
ATOM   541  N N   . CYS A 1 78  ? 170.785 146.801 126.353 1.00 52.16 ? 106 CYS A N   1 
ATOM   542  C CA  . CYS A 1 78  ? 170.624 148.086 125.677 1.00 52.16 ? 106 CYS A CA  1 
ATOM   543  C C   . CYS A 1 78  ? 169.271 148.714 125.976 1.00 52.16 ? 106 CYS A C   1 
ATOM   544  O O   . CYS A 1 78  ? 169.182 149.909 126.295 1.00 52.16 ? 106 CYS A O   1 
ATOM   545  C CB  . CYS A 1 78  ? 170.799 147.892 124.171 1.00 52.16 ? 106 CYS A CB  1 
ATOM   546  S SG  . CYS A 1 78  ? 171.124 149.400 123.268 1.00 52.16 ? 106 CYS A SG  1 
ATOM   547  N N   . GLU A 1 79  ? 168.197 147.935 125.842 1.00 45.97 ? 107 GLU A N   1 
ATOM   548  C CA  . GLU A 1 79  ? 166.879 148.474 126.161 1.00 45.97 ? 107 GLU A CA  1 
ATOM   549  C C   . GLU A 1 79  ? 166.822 148.932 127.612 1.00 45.97 ? 107 GLU A C   1 
ATOM   550  O O   . GLU A 1 79  ? 166.336 150.032 127.916 1.00 45.97 ? 107 GLU A O   1 
ATOM   551  C CB  . GLU A 1 79  ? 165.795 147.432 125.882 1.00 45.97 ? 107 GLU A CB  1 
ATOM   552  C CG  . GLU A 1 79  ? 165.706 146.984 124.433 1.00 45.97 ? 107 GLU A CG  1 
ATOM   553  C CD  . GLU A 1 79  ? 165.957 148.114 123.459 1.00 45.97 ? 107 GLU A CD  1 
ATOM   554  O OE1 . GLU A 1 79  ? 165.029 148.913 123.222 1.00 45.97 ? 107 GLU A OE1 1 
ATOM   555  O OE2 . GLU A 1 79  ? 167.084 148.207 122.932 1.00 45.97 ? 107 GLU A OE2 1 
ATOM   556  N N   . PHE A 1 80  ? 167.347 148.112 128.522 1.00 41.87 ? 108 PHE A N   1 
ATOM   557  C CA  . PHE A 1 80  ? 167.322 148.486 129.931 1.00 41.87 ? 108 PHE A CA  1 
ATOM   558  C C   . PHE A 1 80  ? 168.084 149.781 130.170 1.00 41.87 ? 108 PHE A C   1 
ATOM   559  O O   . PHE A 1 80  ? 167.617 150.661 130.904 1.00 41.87 ? 108 PHE A O   1 
ATOM   560  C CB  . PHE A 1 80  ? 167.902 147.364 130.787 1.00 41.87 ? 108 PHE A CB  1 
ATOM   561  C CG  . PHE A 1 80  ? 167.406 147.371 132.201 1.00 41.87 ? 108 PHE A CG  1 
ATOM   562  C CD1 . PHE A 1 80  ? 166.056 147.232 132.473 1.00 41.87 ? 108 PHE A CD1 1 
ATOM   563  C CD2 . PHE A 1 80  ? 168.286 147.529 133.258 1.00 41.87 ? 108 PHE A CD2 1 
ATOM   564  C CE1 . PHE A 1 80  ? 165.594 147.240 133.771 1.00 41.87 ? 108 PHE A CE1 1 
ATOM   565  C CE2 . PHE A 1 80  ? 167.828 147.539 134.560 1.00 41.87 ? 108 PHE A CE2 1 
ATOM   566  C CZ  . PHE A 1 80  ? 166.480 147.394 134.817 1.00 41.87 ? 108 PHE A CZ  1 
ATOM   567  N N   . TRP A 1 81  ? 169.255 149.921 129.547 1.00 31.99 ? 109 TRP A N   1 
ATOM   568  C CA  . TRP A 1 81  ? 170.091 151.091 129.783 1.00 31.99 ? 109 TRP A CA  1 
ATOM   569  C C   . TRP A 1 81  ? 169.430 152.360 129.259 1.00 31.99 ? 109 TRP A C   1 
ATOM   570  O O   . TRP A 1 81  ? 169.380 153.380 129.962 1.00 31.99 ? 109 TRP A O   1 
ATOM   571  C CB  . TRP A 1 81  ? 171.458 150.877 129.142 1.00 31.99 ? 109 TRP A CB  1 
ATOM   572  C CG  . TRP A 1 81  ? 172.298 152.087 129.074 1.00 31.99 ? 109 TRP A CG  1 
ATOM   573  C CD1 . TRP A 1 81  ? 172.942 152.690 130.104 1.00 31.99 ? 109 TRP A CD1 1 
ATOM   574  C CD2 . TRP A 1 81  ? 172.617 152.840 127.901 1.00 31.99 ? 109 TRP A CD2 1 
ATOM   575  N NE1 . TRP A 1 81  ? 173.637 153.782 129.651 1.00 31.99 ? 109 TRP A NE1 1 
ATOM   576  C CE2 . TRP A 1 81  ? 173.453 153.895 128.300 1.00 31.99 ? 109 TRP A CE2 1 
ATOM   577  C CE3 . TRP A 1 81  ? 172.272 152.726 126.553 1.00 31.99 ? 109 TRP A CE3 1 
ATOM   578  C CZ2 . TRP A 1 81  ? 173.948 154.830 127.402 1.00 31.99 ? 109 TRP A CZ2 1 
ATOM   579  C CZ3 . TRP A 1 81  ? 172.765 153.655 125.664 1.00 31.99 ? 109 TRP A CZ3 1 
ATOM   580  C CH2 . TRP A 1 81  ? 173.593 154.693 126.090 1.00 31.99 ? 109 TRP A CH2 1 
ATOM   581  N N   . THR A 1 82  ? 168.903 152.321 128.031 1.00 30.48 ? 110 THR A N   1 
ATOM   582  C CA  . THR A 1 82  ? 168.256 153.520 127.507 1.00 30.48 ? 110 THR A CA  1 
ATOM   583  C C   . THR A 1 82  ? 167.028 153.885 128.329 1.00 30.48 ? 110 THR A C   1 
ATOM   584  O O   . THR A 1 82  ? 166.745 155.077 128.539 1.00 30.48 ? 110 THR A O   1 
ATOM   585  C CB  . THR A 1 82  ? 167.893 153.350 126.028 1.00 30.48 ? 110 THR A CB  1 
ATOM   586  O OG1 . THR A 1 82  ? 167.297 154.557 125.541 1.00 30.48 ? 110 THR A OG1 1 
ATOM   587  C CG2 . THR A 1 82  ? 166.926 152.212 125.821 1.00 30.48 ? 110 THR A CG2 1 
ATOM   588  N N   . SER A 1 83  ? 166.311 152.885 128.846 1.00 27.29 ? 111 SER A N   1 
ATOM   589  C CA  . SER A 1 83  ? 165.127 153.202 129.631 1.00 27.29 ? 111 SER A CA  1 
ATOM   590  C C   . SER A 1 83  ? 165.503 153.798 130.984 1.00 27.29 ? 111 SER A C   1 
ATOM   591  O O   . SER A 1 83  ? 164.830 154.714 131.469 1.00 27.29 ? 111 SER A O   1 
ATOM   592  C CB  . SER A 1 83  ? 164.264 151.959 129.798 1.00 27.29 ? 111 SER A CB  1 
ATOM   593  O OG  . SER A 1 83  ? 163.032 152.299 130.397 1.00 27.29 ? 111 SER A OG  1 
ATOM   594  N N   . ILE A 1 84  ? 166.578 153.308 131.606 1.00 18.96 ? 112 ILE A N   1 
ATOM   595  C CA  . ILE A 1 84  ? 167.047 153.935 132.840 1.00 18.96 ? 112 ILE A CA  1 
ATOM   596  C C   . ILE A 1 84  ? 167.462 155.376 132.579 1.00 18.96 ? 112 ILE A C   1 
ATOM   597  O O   . ILE A 1 84  ? 167.194 156.272 133.389 1.00 18.96 ? 112 ILE A O   1 
ATOM   598  C CB  . ILE A 1 84  ? 168.193 153.122 133.470 1.00 18.96 ? 112 ILE A CB  1 
ATOM   599  C CG1 . ILE A 1 84  ? 167.650 151.873 134.157 1.00 18.96 ? 112 ILE A CG1 1 
ATOM   600  C CG2 . ILE A 1 84  ? 168.960 153.958 134.470 1.00 18.96 ? 112 ILE A CG2 1 
ATOM   601  C CD1 . ILE A 1 84  ? 168.727 150.996 134.749 1.00 18.96 ? 112 ILE A CD1 1 
ATOM   602  N N   . ASP A 1 85  ? 168.123 155.622 131.445 1.00 20.23 ? 113 ASP A N   1 
ATOM   603  C CA  . ASP A 1 85  ? 168.514 156.983 131.079 1.00 20.23 ? 113 ASP A CA  1 
ATOM   604  C C   . ASP A 1 85  ? 167.307 157.918 131.029 1.00 20.23 ? 113 ASP A C   1 
ATOM   605  O O   . ASP A 1 85  ? 167.282 158.977 131.685 1.00 20.23 ? 113 ASP A O   1 
ATOM   606  C CB  . ASP A 1 85  ? 169.213 156.944 129.723 1.00 20.23 ? 113 ASP A CB  1 
ATOM   607  C CG  . ASP A 1 85  ? 169.819 158.262 129.338 1.00 20.23 ? 113 ASP A CG  1 
ATOM   608  O OD1 . ASP A 1 85  ? 169.694 159.234 130.108 1.00 20.23 ? 113 ASP A OD1 1 
ATOM   609  O OD2 . ASP A 1 85  ? 170.405 158.331 128.239 1.00 20.23 ? 113 ASP A OD2 1 
ATOM   610  N N   . VAL A 1 86  ? 166.290 157.530 130.257 1.00 15.05 ? 114 VAL A N   1 
ATOM   611  C CA  . VAL A 1 86  ? 165.107 158.373 130.110 1.00 15.05 ? 114 VAL A CA  1 
ATOM   612  C C   . VAL A 1 86  ? 164.415 158.563 131.455 1.00 15.05 ? 114 VAL A C   1 
ATOM   613  O O   . VAL A 1 86  ? 163.966 159.670 131.791 1.00 15.05 ? 114 VAL A O   1 
ATOM   614  C CB  . VAL A 1 86  ? 164.157 157.772 129.063 1.00 15.05 ? 114 VAL A CB  1 
ATOM   615  C CG1 . VAL A 1 86  ? 162.848 158.508 129.064 1.00 15.05 ? 114 VAL A CG1 1 
ATOM   616  C CG2 . VAL A 1 86  ? 164.789 157.826 127.696 1.00 15.05 ? 114 VAL A CG2 1 
ATOM   617  N N   . LEU A 1 87  ? 164.329 157.493 132.251 1.00 16.10 ? 115 LEU A N   1 
ATOM   618  C CA  . LEU A 1 87  ? 163.689 157.584 133.558 1.00 16.10 ? 115 LEU A CA  1 
ATOM   619  C C   . LEU A 1 87  ? 164.396 158.594 134.444 1.00 16.10 ? 115 LEU A C   1 
ATOM   620  O O   . LEU A 1 87  ? 163.749 159.409 135.108 1.00 16.10 ? 115 LEU A O   1 
ATOM   621  C CB  . LEU A 1 87  ? 163.673 156.213 134.231 1.00 16.10 ? 115 LEU A CB  1 
ATOM   622  C CG  . LEU A 1 87  ? 162.689 155.991 135.381 1.00 16.10 ? 115 LEU A CG  1 
ATOM   623  C CD1 . LEU A 1 87  ? 162.425 154.515 135.537 1.00 16.10 ? 115 LEU A CD1 1 
ATOM   624  C CD2 . LEU A 1 87  ? 163.199 156.552 136.685 1.00 16.10 ? 115 LEU A CD2 1 
ATOM   625  N N   . CYS A 1 88  ? 165.725 158.544 134.484 1.00 13.97 ? 116 CYS A N   1 
ATOM   626  C CA  . CYS A 1 88  ? 166.449 159.432 135.382 1.00 13.97 ? 116 CYS A CA  1 
ATOM   627  C C   . CYS A 1 88  ? 166.278 160.889 134.979 1.00 13.97 ? 116 CYS A C   1 
ATOM   628  O O   . CYS A 1 88  ? 166.031 161.753 135.835 1.00 13.97 ? 116 CYS A O   1 
ATOM   629  C CB  . CYS A 1 88  ? 167.917 159.043 135.419 1.00 13.97 ? 116 CYS A CB  1 
ATOM   630  S SG  . CYS A 1 88  ? 168.244 157.660 136.516 1.00 13.97 ? 116 CYS A SG  1 
ATOM   631  N N   . VAL A 1 89  ? 166.376 161.186 133.678 1.00 11.07 ? 117 VAL A N   1 
ATOM   632  C CA  . VAL A 1 89  ? 166.223 162.579 133.248 1.00 11.07 ? 117 VAL A CA  1 
ATOM   633  C C   . VAL A 1 89  ? 164.820 163.094 133.563 1.00 11.07 ? 117 VAL A C   1 
ATOM   634  O O   . VAL A 1 89  ? 164.650 164.188 134.125 1.00 11.07 ? 117 VAL A O   1 
ATOM   635  C CB  . VAL A 1 89  ? 166.552 162.728 131.756 1.00 11.07 ? 117 VAL A CB  1 
ATOM   636  C CG1 . VAL A 1 89  ? 166.023 164.045 131.243 1.00 11.07 ? 117 VAL A CG1 1 
ATOM   637  C CG2 . VAL A 1 89  ? 168.047 162.644 131.550 1.00 11.07 ? 117 VAL A CG2 1 
ATOM   638  N N   . THR A 1 90  ? 163.791 162.313 133.215 1.00 10.94 ? 118 THR A N   1 
ATOM   639  C CA  . THR A 1 90  ? 162.426 162.765 133.465 1.00 10.94 ? 118 THR A CA  1 
ATOM   640  C C   . THR A 1 90  ? 162.157 162.930 134.956 1.00 10.94 ? 118 THR A C   1 
ATOM   641  O O   . THR A 1 90  ? 161.514 163.900 135.373 1.00 10.94 ? 118 THR A O   1 
ATOM   642  C CB  . THR A 1 90  ? 161.424 161.794 132.847 1.00 10.94 ? 118 THR A CB  1 
ATOM   643  O OG1 . THR A 1 90  ? 161.707 161.641 131.454 1.00 10.94 ? 118 THR A OG1 1 
ATOM   644  C CG2 . THR A 1 90  ? 160.019 162.325 132.999 1.00 10.94 ? 118 THR A CG2 1 
ATOM   645  N N   . ALA A 1 91  ? 162.640 161.998 135.780 1.00 10.42 ? 119 ALA A N   1 
ATOM   646  C CA  . ALA A 1 91  ? 162.409 162.095 137.216 1.00 10.42 ? 119 ALA A CA  1 
ATOM   647  C C   . ALA A 1 91  ? 163.053 163.343 137.797 1.00 10.42 ? 119 ALA A C   1 
ATOM   648  O O   . ALA A 1 91  ? 162.449 164.031 138.631 1.00 10.42 ? 119 ALA A O   1 
ATOM   649  C CB  . ALA A 1 91  ? 162.938 160.849 137.918 1.00 10.42 ? 119 ALA A CB  1 
ATOM   650  N N   . SER A 1 92  ? 164.280 163.656 137.375 1.00 8.16  ? 120 SER A N   1 
ATOM   651  C CA  . SER A 1 92  ? 164.925 164.862 137.883 1.00 8.16  ? 120 SER A CA  1 
ATOM   652  C C   . SER A 1 92  ? 164.144 166.110 137.485 1.00 8.16  ? 120 SER A C   1 
ATOM   653  O O   . SER A 1 92  ? 163.887 166.992 138.321 1.00 8.16  ? 120 SER A O   1 
ATOM   654  C CB  . SER A 1 92  ? 166.366 164.936 137.382 1.00 8.16  ? 120 SER A CB  1 
ATOM   655  O OG  . SER A 1 92  ? 167.078 165.960 138.048 1.00 8.16  ? 120 SER A OG  1 
ATOM   656  N N   . ILE A 1 93  ? 163.732 166.196 136.215 1.00 9.95  ? 121 ILE A N   1 
ATOM   657  C CA  . ILE A 1 93  ? 163.038 167.411 135.791 1.00 9.95  ? 121 ILE A CA  1 
ATOM   658  C C   . ILE A 1 93  ? 161.682 167.544 136.468 1.00 9.95  ? 121 ILE A C   1 
ATOM   659  O O   . ILE A 1 93  ? 161.206 168.662 136.684 1.00 9.95  ? 121 ILE A O   1 
ATOM   660  C CB  . ILE A 1 93  ? 162.905 167.489 134.261 1.00 9.95  ? 121 ILE A CB  1 
ATOM   661  C CG1 . ILE A 1 93  ? 162.462 168.888 133.859 1.00 9.95  ? 121 ILE A CG1 1 
ATOM   662  C CG2 . ILE A 1 93  ? 161.885 166.518 133.756 1.00 9.95  ? 121 ILE A CG2 1 
ATOM   663  C CD1 . ILE A 1 93  ? 163.461 169.946 134.155 1.00 9.95  ? 121 ILE A CD1 1 
ATOM   664  N N   . GLU A 1 94  ? 161.031 166.435 136.814 1.00 10.27 ? 122 GLU A N   1 
ATOM   665  C CA  . GLU A 1 94  ? 159.742 166.563 137.488 1.00 10.27 ? 122 GLU A CA  1 
ATOM   666  C C   . GLU A 1 94  ? 159.902 166.925 138.962 1.00 10.27 ? 122 GLU A C   1 
ATOM   667  O O   . GLU A 1 94  ? 159.120 167.724 139.495 1.00 10.27 ? 122 GLU A O   1 
ATOM   668  C CB  . GLU A 1 94  ? 158.937 165.279 137.326 1.00 10.27 ? 122 GLU A CB  1 
ATOM   669  C CG  . GLU A 1 94  ? 158.663 164.899 135.883 1.00 10.27 ? 122 GLU A CG  1 
ATOM   670  C CD  . GLU A 1 94  ? 157.219 165.078 135.489 1.00 10.27 ? 122 GLU A CD  1 
ATOM   671  O OE1 . GLU A 1 94  ? 156.878 164.774 134.329 1.00 10.27 ? 122 GLU A OE1 1 
ATOM   672  O OE2 . GLU A 1 94  ? 156.421 165.523 136.336 1.00 10.27 ? 122 GLU A OE2 1 
ATOM   673  N N   . THR A 1 95  ? 160.907 166.364 139.645 1.00 10.53 ? 123 THR A N   1 
ATOM   674  C CA  . THR A 1 95  ? 161.104 166.751 141.040 1.00 10.53 ? 123 THR A CA  1 
ATOM   675  C C   . THR A 1 95  ? 161.541 168.204 141.163 1.00 10.53 ? 123 THR A C   1 
ATOM   676  O O   . THR A 1 95  ? 161.260 168.846 142.183 1.00 10.53 ? 123 THR A O   1 
ATOM   677  C CB  . THR A 1 95  ? 162.119 165.847 141.731 1.00 10.53 ? 123 THR A CB  1 
ATOM   678  O OG1 . THR A 1 95  ? 163.369 165.913 141.042 1.00 10.53 ? 123 THR A OG1 1 
ATOM   679  C CG2 . THR A 1 95  ? 161.624 164.420 141.752 1.00 10.53 ? 123 THR A CG2 1 
ATOM   680  N N   . LEU A 1 96  ? 162.209 168.752 140.144 1.00 9.27  ? 124 LEU A N   1 
ATOM   681  C CA  . LEU A 1 96  ? 162.547 170.173 140.197 1.00 9.27  ? 124 LEU A CA  1 
ATOM   682  C C   . LEU A 1 96  ? 161.292 171.044 140.247 1.00 9.27  ? 124 LEU A C   1 
ATOM   683  O O   . LEU A 1 96  ? 161.197 171.968 141.064 1.00 9.27  ? 124 LEU A O   1 
ATOM   684  C CB  . LEU A 1 96  ? 163.425 170.554 139.009 1.00 9.27  ? 124 LEU A CB  1 
ATOM   685  C CG  . LEU A 1 96  ? 164.916 170.408 139.291 1.00 9.27  ? 124 LEU A CG  1 
ATOM   686  C CD1 . LEU A 1 96  ? 165.741 170.839 138.099 1.00 9.27  ? 124 LEU A CD1 1 
ATOM   687  C CD2 . LEU A 1 96  ? 165.283 171.212 140.511 1.00 9.27  ? 124 LEU A CD2 1 
ATOM   688  N N   . CYS A 1 97  ? 160.303 170.755 139.396 1.00 11.19 ? 125 CYS A N   1 
ATOM   689  C CA  . CYS A 1 97  ? 159.088 171.563 139.423 1.00 11.19 ? 125 CYS A CA  1 
ATOM   690  C C   . CYS A 1 97  ? 158.259 171.282 140.670 1.00 11.19 ? 125 CYS A C   1 
ATOM   691  O O   . CYS A 1 97  ? 157.550 172.175 141.152 1.00 11.19 ? 125 CYS A O   1 
ATOM   692  C CB  . CYS A 1 97  ? 158.251 171.341 138.165 1.00 11.19 ? 125 CYS A CB  1 
ATOM   693  S SG  . CYS A 1 97  ? 157.427 169.755 138.042 1.00 11.19 ? 125 CYS A SG  1 
ATOM   694  N N   . VAL A 1 98  ? 158.339 170.065 141.218 1.00 12.72 ? 126 VAL A N   1 
ATOM   695  C CA  . VAL A 1 98  ? 157.703 169.816 142.512 1.00 12.72 ? 126 VAL A CA  1 
ATOM   696  C C   . VAL A 1 98  ? 158.301 170.716 143.584 1.00 12.72 ? 126 VAL A C   1 
ATOM   697  O O   . VAL A 1 98  ? 157.574 171.308 144.389 1.00 12.72 ? 126 VAL A O   1 
ATOM   698  C CB  . VAL A 1 98  ? 157.808 168.334 142.905 1.00 12.72 ? 126 VAL A CB  1 
ATOM   699  C CG1 . VAL A 1 98  ? 157.248 168.132 144.289 1.00 12.72 ? 126 VAL A CG1 1 
ATOM   700  C CG2 . VAL A 1 98  ? 157.037 167.482 141.926 1.00 12.72 ? 126 VAL A CG2 1 
ATOM   701  N N   . ILE A 1 99  ? 159.631 170.837 143.611 1.00 13.24 ? 127 ILE A N   1 
ATOM   702  C CA  . ILE A 1 99  ? 160.271 171.739 144.568 1.00 13.24 ? 127 ILE A CA  1 
ATOM   703  C C   . ILE A 1 99  ? 159.819 173.175 144.337 1.00 13.24 ? 127 ILE A C   1 
ATOM   704  O O   . ILE A 1 99  ? 159.565 173.923 145.290 1.00 13.24 ? 127 ILE A O   1 
ATOM   705  C CB  . ILE A 1 99  ? 161.803 171.617 144.490 1.00 13.24 ? 127 ILE A CB  1 
ATOM   706  C CG1 . ILE A 1 99  ? 162.275 170.355 145.198 1.00 13.24 ? 127 ILE A CG1 1 
ATOM   707  C CG2 . ILE A 1 99  ? 162.465 172.826 145.106 1.00 13.24 ? 127 ILE A CG2 1 
ATOM   708  C CD1 . ILE A 1 99  ? 163.769 170.164 145.163 1.00 13.24 ? 127 ILE A CD1 1 
ATOM   709  N N   . ALA A 1 100 ? 159.721 173.586 143.072 1.00 14.12 ? 128 ALA A N   1 
ATOM   710  C CA  . ALA A 1 100 ? 159.311 174.957 142.772 1.00 14.12 ? 128 ALA A CA  1 
ATOM   711  C C   . ALA A 1 100 ? 157.913 175.250 143.307 1.00 14.12 ? 128 ALA A C   1 
ATOM   712  O O   . ALA A 1 100 ? 157.687 176.278 143.958 1.00 14.12 ? 128 ALA A O   1 
ATOM   713  C CB  . ALA A 1 100 ? 159.369 175.205 141.268 1.00 14.12 ? 128 ALA A CB  1 
ATOM   714  N N   . VAL A 1 101 ? 156.960 174.354 143.050 1.00 15.90 ? 129 VAL A N   1 
ATOM   715  C CA  . VAL A 1 101 ? 155.595 174.581 143.523 1.00 15.90 ? 129 VAL A CA  1 
ATOM   716  C C   . VAL A 1 101 ? 155.531 174.519 145.046 1.00 15.90 ? 129 VAL A C   1 
ATOM   717  O O   . VAL A 1 101 ? 154.785 175.278 145.683 1.00 15.90 ? 129 VAL A O   1 
ATOM   718  C CB  . VAL A 1 101 ? 154.627 173.582 142.868 1.00 15.90 ? 129 VAL A CB  1 
ATOM   719  C CG1 . VAL A 1 101 ? 153.241 173.726 143.459 1.00 15.90 ? 129 VAL A CG1 1 
ATOM   720  C CG2 . VAL A 1 101 ? 154.580 173.816 141.374 1.00 15.90 ? 129 VAL A CG2 1 
ATOM   721  N N   . ASP A 1 102 ? 156.307 173.620 145.655 1.00 23.89 ? 130 ASP A N   1 
ATOM   722  C CA  . ASP A 1 102 ? 156.379 173.565 147.111 1.00 23.89 ? 130 ASP A CA  1 
ATOM   723  C C   . ASP A 1 102 ? 156.827 174.901 147.682 1.00 23.89 ? 130 ASP A C   1 
ATOM   724  O O   . ASP A 1 102 ? 156.231 175.416 148.634 1.00 23.89 ? 130 ASP A O   1 
ATOM   725  C CB  . ASP A 1 102 ? 157.335 172.452 147.537 1.00 23.89 ? 130 ASP A CB  1 
ATOM   726  C CG  . ASP A 1 102 ? 157.802 172.596 148.968 1.00 23.89 ? 130 ASP A CG  1 
ATOM   727  O OD1 . ASP A 1 102 ? 156.991 172.983 149.832 1.00 23.89 ? 130 ASP A OD1 1 
ATOM   728  O OD2 . ASP A 1 102 ? 158.990 172.323 149.230 1.00 23.89 ? 130 ASP A OD2 1 
ATOM   729  N N   . ARG A 1 103 ? 157.877 175.481 147.107 1.00 23.40 ? 131 ARG A N   1 
ATOM   730  C CA  . ARG A 1 103 ? 158.372 176.752 147.620 1.00 23.40 ? 131 ARG A CA  1 
ATOM   731  C C   . ARG A 1 103 ? 157.374 177.875 147.375 1.00 23.40 ? 131 ARG A C   1 
ATOM   732  O O   . ARG A 1 103 ? 157.233 178.780 148.207 1.00 23.40 ? 131 ARG A O   1 
ATOM   733  C CB  . ARG A 1 103 ? 159.729 177.075 147.000 1.00 23.40 ? 131 ARG A CB  1 
ATOM   734  C CG  . ARG A 1 103 ? 160.406 178.313 147.553 1.00 23.40 ? 131 ARG A CG  1 
ATOM   735  C CD  . ARG A 1 103 ? 160.380 178.400 149.081 1.00 23.40 ? 131 ARG A CD  1 
ATOM   736  N NE  . ARG A 1 103 ? 160.514 177.116 149.763 1.00 23.40 ? 131 ARG A NE  1 
ATOM   737  C CZ  . ARG A 1 103 ? 161.629 176.400 149.808 1.00 23.40 ? 131 ARG A CZ  1 
ATOM   738  N NH1 . ARG A 1 103 ? 162.725 176.836 149.208 1.00 23.40 ? 131 ARG A NH1 1 
ATOM   739  N NH2 . ARG A 1 103 ? 161.647 175.245 150.457 1.00 23.40 ? 131 ARG A NH2 1 
ATOM   740  N N   . TYR A 1 104 ? 156.661 177.831 146.248 1.00 26.81 ? 132 TYR A N   1 
ATOM   741  C CA  . TYR A 1 104 ? 155.628 178.833 146.006 1.00 26.81 ? 132 TYR A CA  1 
ATOM   742  C C   . TYR A 1 104 ? 154.550 178.776 147.081 1.00 26.81 ? 132 TYR A C   1 
ATOM   743  O O   . TYR A 1 104 ? 154.133 179.811 147.615 1.00 26.81 ? 132 TYR A O   1 
ATOM   744  C CB  . TYR A 1 104 ? 155.008 178.636 144.627 1.00 26.81 ? 132 TYR A CB  1 
ATOM   745  C CG  . TYR A 1 104 ? 153.688 179.343 144.464 1.00 26.81 ? 132 TYR A CG  1 
ATOM   746  C CD1 . TYR A 1 104 ? 152.497 178.635 144.456 1.00 26.81 ? 132 TYR A CD1 1 
ATOM   747  C CD2 . TYR A 1 104 ? 153.633 180.718 144.324 1.00 26.81 ? 132 TYR A CD2 1 
ATOM   748  C CE1 . TYR A 1 104 ? 151.288 179.276 144.310 1.00 26.81 ? 132 TYR A CE1 1 
ATOM   749  C CE2 . TYR A 1 104 ? 152.428 181.371 144.177 1.00 26.81 ? 132 TYR A CE2 1 
ATOM   750  C CZ  . TYR A 1 104 ? 151.259 180.646 144.171 1.00 26.81 ? 132 TYR A CZ  1 
ATOM   751  O OH  . TYR A 1 104 ? 150.054 181.294 144.026 1.00 26.81 ? 132 TYR A OH  1 
ATOM   752  N N   . PHE A 1 105 ? 154.089 177.570 147.414 1.00 31.74 ? 133 PHE A N   1 
ATOM   753  C CA  . PHE A 1 105 ? 153.062 177.446 148.446 1.00 31.74 ? 133 PHE A CA  1 
ATOM   754  C C   . PHE A 1 105 ? 153.604 177.821 149.819 1.00 31.74 ? 133 PHE A C   1 
ATOM   755  O O   . PHE A 1 105 ? 152.865 178.342 150.660 1.00 31.74 ? 133 PHE A O   1 
ATOM   756  C CB  . PHE A 1 105 ? 152.486 176.032 148.463 1.00 31.74 ? 133 PHE A CB  1 
ATOM   757  C CG  . PHE A 1 105 ? 151.233 175.880 147.648 1.00 31.74 ? 133 PHE A CG  1 
ATOM   758  C CD1 . PHE A 1 105 ? 150.006 176.255 148.167 1.00 31.74 ? 133 PHE A CD1 1 
ATOM   759  C CD2 . PHE A 1 105 ? 151.281 175.370 146.362 1.00 31.74 ? 133 PHE A CD2 1 
ATOM   760  C CE1 . PHE A 1 105 ? 148.852 176.120 147.421 1.00 31.74 ? 133 PHE A CE1 1 
ATOM   761  C CE2 . PHE A 1 105 ? 150.130 175.233 145.612 1.00 31.74 ? 133 PHE A CE2 1 
ATOM   762  C CZ  . PHE A 1 105 ? 148.914 175.609 146.142 1.00 31.74 ? 133 PHE A CZ  1 
ATOM   763  N N   . ALA A 1 106 ? 154.888 177.561 150.068 1.00 34.02 ? 134 ALA A N   1 
ATOM   764  C CA  . ALA A 1 106 ? 155.463 177.906 151.363 1.00 34.02 ? 134 ALA A CA  1 
ATOM   765  C C   . ALA A 1 106 ? 155.629 179.410 151.529 1.00 34.02 ? 134 ALA A C   1 
ATOM   766  O O   . ALA A 1 106 ? 155.546 179.918 152.651 1.00 34.02 ? 134 ALA A O   1 
ATOM   767  C CB  . ALA A 1 106 ? 156.805 177.205 151.552 1.00 34.02 ? 134 ALA A CB  1 
ATOM   768  N N   . ILE A 1 107 ? 155.877 180.135 150.442 1.00 30.46 ? 135 ILE A N   1 
ATOM   769  C CA  . ILE A 1 107 ? 156.039 181.584 150.540 1.00 30.46 ? 135 ILE A CA  1 
ATOM   770  C C   . ILE A 1 107 ? 154.698 182.309 150.503 1.00 30.46 ? 135 ILE A C   1 
ATOM   771  O O   . ILE A 1 107 ? 154.504 183.292 151.222 1.00 30.46 ? 135 ILE A O   1 
ATOM   772  C CB  . ILE A 1 107 ? 156.989 182.094 149.438 1.00 30.46 ? 135 ILE A CB  1 
ATOM   773  C CG1 . ILE A 1 107 ? 158.422 181.677 149.746 1.00 30.46 ? 135 ILE A CG1 1 
ATOM   774  C CG2 . ILE A 1 107 ? 156.905 183.599 149.295 1.00 30.46 ? 135 ILE A CG2 1 
ATOM   775  C CD1 . ILE A 1 107 ? 159.394 182.014 148.654 1.00 30.46 ? 135 ILE A CD1 1 
ATOM   776  N N   . THR A 1 108 ? 153.746 181.849 149.689 1.00 36.06 ? 136 THR A N   1 
ATOM   777  C CA  . THR A 1 108 ? 152.501 182.599 149.549 1.00 36.06 ? 136 THR A CA  1 
ATOM   778  C C   . THR A 1 108 ? 151.675 182.602 150.834 1.00 36.06 ? 136 THR A C   1 
ATOM   779  O O   . THR A 1 108 ? 150.899 183.537 151.059 1.00 36.06 ? 136 THR A O   1 
ATOM   780  C CB  . THR A 1 108 ? 151.674 182.047 148.386 1.00 36.06 ? 136 THR A CB  1 
ATOM   781  O OG1 . THR A 1 108 ? 150.609 182.957 148.087 1.00 36.06 ? 136 THR A OG1 1 
ATOM   782  C CG2 . THR A 1 108 ? 151.084 180.688 148.733 1.00 36.06 ? 136 THR A CG2 1 
ATOM   783  N N   . SER A 1 109 ? 151.820 181.581 151.685 1.00 41.68 ? 137 SER A N   1 
ATOM   784  C CA  . SER A 1 109 ? 151.069 181.506 152.936 1.00 41.68 ? 137 SER A CA  1 
ATOM   785  C C   . SER A 1 109 ? 151.757 180.556 153.908 1.00 41.68 ? 137 SER A C   1 
ATOM   786  O O   . SER A 1 109 ? 151.453 179.357 153.918 1.00 41.68 ? 137 SER A O   1 
ATOM   787  C CB  . SER A 1 109 ? 149.633 181.050 152.682 1.00 41.68 ? 137 SER A CB  1 
ATOM   788  O OG  . SER A 1 109 ? 149.597 179.697 152.267 1.00 41.68 ? 137 SER A OG  1 
ATOM   789  N N   . PRO A 1 110 ? 152.680 181.052 154.738 1.00 50.16 ? 138 PRO A N   1 
ATOM   790  C CA  . PRO A 1 110 ? 153.516 180.138 155.539 1.00 50.16 ? 138 PRO A CA  1 
ATOM   791  C C   . PRO A 1 110 ? 152.739 179.199 156.446 1.00 50.16 ? 138 PRO A C   1 
ATOM   792  O O   . PRO A 1 110 ? 153.119 178.029 156.580 1.00 50.16 ? 138 PRO A O   1 
ATOM   793  C CB  . PRO A 1 110 ? 154.398 181.099 156.351 1.00 50.16 ? 138 PRO A CB  1 
ATOM   794  C CG  . PRO A 1 110 ? 154.378 182.380 155.593 1.00 50.16 ? 138 PRO A CG  1 
ATOM   795  C CD  . PRO A 1 110 ? 153.025 182.464 154.962 1.00 50.16 ? 138 PRO A CD  1 
ATOM   796  N N   . PHE A 1 111 ? 151.660 179.671 157.073 1.00 62.34 ? 139 PHE A N   1 
ATOM   797  C CA  . PHE A 1 111 ? 150.967 178.850 158.063 1.00 62.34 ? 139 PHE A CA  1 
ATOM   798  C C   . PHE A 1 111 ? 150.291 177.645 157.420 1.00 62.34 ? 139 PHE A C   1 
ATOM   799  O O   . PHE A 1 111 ? 150.329 176.538 157.973 1.00 62.34 ? 139 PHE A O   1 
ATOM   800  C CB  . PHE A 1 111 ? 149.950 179.698 158.825 1.00 62.34 ? 139 PHE A CB  1 
ATOM   801  C CG  . PHE A 1 111 ? 150.521 180.973 159.375 1.00 62.34 ? 139 PHE A CG  1 
ATOM   802  C CD1 . PHE A 1 111 ? 151.656 180.953 160.168 1.00 62.34 ? 139 PHE A CD1 1 
ATOM   803  C CD2 . PHE A 1 111 ? 149.925 182.192 159.097 1.00 62.34 ? 139 PHE A CD2 1 
ATOM   804  C CE1 . PHE A 1 111 ? 152.186 182.124 160.675 1.00 62.34 ? 139 PHE A CE1 1 
ATOM   805  C CE2 . PHE A 1 111 ? 150.452 183.367 159.602 1.00 62.34 ? 139 PHE A CE2 1 
ATOM   806  C CZ  . PHE A 1 111 ? 151.583 183.332 160.391 1.00 62.34 ? 139 PHE A CZ  1 
ATOM   807  N N   . LYS A 1 112 ? 149.662 177.839 156.259 1.00 57.64 ? 140 LYS A N   1 
ATOM   808  C CA  . LYS A 1 112 ? 148.970 176.735 155.602 1.00 57.64 ? 140 LYS A CA  1 
ATOM   809  C C   . LYS A 1 112 ? 149.942 175.636 155.196 1.00 57.64 ? 140 LYS A C   1 
ATOM   810  O O   . LYS A 1 112 ? 149.663 174.448 155.392 1.00 57.64 ? 140 LYS A O   1 
ATOM   811  C CB  . LYS A 1 112 ? 148.195 177.248 154.389 1.00 57.64 ? 140 LYS A CB  1 
ATOM   812  C CG  . LYS A 1 112 ? 147.035 178.163 154.744 1.00 57.64 ? 140 LYS A CG  1 
ATOM   813  C CD  . LYS A 1 112 ? 146.307 178.647 153.502 1.00 57.64 ? 140 LYS A CD  1 
ATOM   814  C CE  . LYS A 1 112 ? 145.551 177.517 152.823 1.00 57.64 ? 140 LYS A CE  1 
ATOM   815  N NZ  . LYS A 1 112 ? 145.001 177.935 151.504 1.00 57.64 ? 140 LYS A NZ  1 
ATOM   816  N N   . TYR A 1 113 ? 151.093 176.011 154.632 1.00 56.56 ? 141 TYR A N   1 
ATOM   817  C CA  . TYR A 1 113 ? 152.097 175.011 154.286 1.00 56.56 ? 141 TYR A CA  1 
ATOM   818  C C   . TYR A 1 113 ? 152.674 174.359 155.535 1.00 56.56 ? 141 TYR A C   1 
ATOM   819  O O   . TYR A 1 113 ? 152.938 173.152 155.547 1.00 56.56 ? 141 TYR A O   1 
ATOM   820  C CB  . TYR A 1 113 ? 153.211 175.639 153.448 1.00 56.56 ? 141 TYR A CB  1 
ATOM   821  C CG  . TYR A 1 113 ? 154.518 174.880 153.511 1.00 56.56 ? 141 TYR A CG  1 
ATOM   822  C CD1 . TYR A 1 113 ? 154.704 173.718 152.774 1.00 56.56 ? 141 TYR A CD1 1 
ATOM   823  C CD2 . TYR A 1 113 ? 155.562 175.321 154.310 1.00 56.56 ? 141 TYR A CD2 1 
ATOM   824  C CE1 . TYR A 1 113 ? 155.893 173.021 152.832 1.00 56.56 ? 141 TYR A CE1 1 
ATOM   825  C CE2 . TYR A 1 113 ? 156.753 174.630 154.374 1.00 56.56 ? 141 TYR A CE2 1 
ATOM   826  C CZ  . TYR A 1 113 ? 156.913 173.482 153.634 1.00 56.56 ? 141 TYR A CZ  1 
ATOM   827  O OH  . TYR A 1 113 ? 158.101 172.793 153.699 1.00 56.56 ? 141 TYR A OH  1 
ATOM   828  N N   . GLN A 1 114 ? 152.879 175.144 156.593 1.00 57.73 ? 142 GLN A N   1 
ATOM   829  C CA  . GLN A 1 114 ? 153.440 174.597 157.823 1.00 57.73 ? 142 GLN A CA  1 
ATOM   830  C C   . GLN A 1 114 ? 152.519 173.548 158.429 1.00 57.73 ? 142 GLN A C   1 
ATOM   831  O O   . GLN A 1 114 ? 152.984 172.523 158.943 1.00 57.73 ? 142 GLN A O   1 
ATOM   832  C CB  . GLN A 1 114 ? 153.699 175.726 158.821 1.00 57.73 ? 142 GLN A CB  1 
ATOM   833  C CG  . GLN A 1 114 ? 154.482 175.305 160.050 1.00 57.73 ? 142 GLN A CG  1 
ATOM   834  C CD  . GLN A 1 114 ? 155.690 174.463 159.704 1.00 57.73 ? 142 GLN A CD  1 
ATOM   835  O OE1 . GLN A 1 114 ? 155.722 173.263 159.972 1.00 57.73 ? 142 GLN A OE1 1 
ATOM   836  N NE2 . GLN A 1 114 ? 156.693 175.090 159.102 1.00 57.73 ? 142 GLN A NE2 1 
ATOM   837  N N   . SER A 1 115 ? 151.209 173.783 158.375 1.00 63.20 ? 143 SER A N   1 
ATOM   838  C CA  . SER A 1 115 ? 150.253 172.887 159.014 1.00 63.20 ? 143 SER A CA  1 
ATOM   839  C C   . SER A 1 115 ? 149.868 171.704 158.128 1.00 63.20 ? 143 SER A C   1 
ATOM   840  O O   . SER A 1 115 ? 149.894 170.556 158.582 1.00 63.20 ? 143 SER A O   1 
ATOM   841  C CB  . SER A 1 115 ? 149.000 173.668 159.419 1.00 63.20 ? 143 SER A CB  1 
ATOM   842  O OG  . SER A 1 115 ? 148.468 174.385 158.319 1.00 63.20 ? 143 SER A OG  1 
ATOM   843  N N   . LEU A 1 116 ? 149.505 171.963 156.870 1.00 62.94 ? 144 LEU A N   1 
ATOM   844  C CA  . LEU A 1 116 ? 148.925 170.913 156.037 1.00 62.94 ? 144 LEU A CA  1 
ATOM   845  C C   . LEU A 1 116 ? 149.964 169.868 155.639 1.00 62.94 ? 144 LEU A C   1 
ATOM   846  O O   . LEU A 1 116 ? 149.714 168.662 155.746 1.00 62.94 ? 144 LEU A O   1 
ATOM   847  C CB  . LEU A 1 116 ? 148.275 171.533 154.799 1.00 62.94 ? 144 LEU A CB  1 
ATOM   848  C CG  . LEU A 1 116 ? 147.335 170.644 153.979 1.00 62.94 ? 144 LEU A CG  1 
ATOM   849  C CD1 . LEU A 1 116 ? 146.181 171.466 153.426 1.00 62.94 ? 144 LEU A CD1 1 
ATOM   850  C CD2 . LEU A 1 116 ? 148.075 169.946 152.845 1.00 62.94 ? 144 LEU A CD2 1 
ATOM   851  N N   . LEU A 1 117 ? 151.133 170.306 155.179 1.00 61.63 ? 145 LEU A N   1 
ATOM   852  C CA  . LEU A 1 117 ? 152.123 169.385 154.634 1.00 61.63 ? 145 LEU A CA  1 
ATOM   853  C C   . LEU A 1 117 ? 152.922 168.726 155.750 1.00 61.63 ? 145 LEU A C   1 
ATOM   854  O O   . LEU A 1 117 ? 153.480 169.407 156.615 1.00 61.63 ? 145 LEU A O   1 
ATOM   855  C CB  . LEU A 1 117 ? 153.062 170.114 153.675 1.00 61.63 ? 145 LEU A CB  1 
ATOM   856  C CG  . LEU A 1 117 ? 152.640 170.132 152.206 1.00 61.63 ? 145 LEU A CG  1 
ATOM   857  C CD1 . LEU A 1 117 ? 151.530 171.143 151.974 1.00 61.63 ? 145 LEU A CD1 1 
ATOM   858  C CD2 . LEU A 1 117 ? 153.832 170.429 151.313 1.00 61.63 ? 145 LEU A CD2 1 
ATOM   859  N N   . THR A 1 118 ? 152.979 167.396 155.723 1.00 55.46 ? 146 THR A N   1 
ATOM   860  C CA  . THR A 1 118 ? 153.715 166.605 156.699 1.00 55.46 ? 146 THR A CA  1 
ATOM   861  C C   . THR A 1 118 ? 154.683 165.681 155.968 1.00 55.46 ? 146 THR A C   1 
ATOM   862  O O   . THR A 1 118 ? 154.755 165.667 154.736 1.00 55.46 ? 146 THR A O   1 
ATOM   863  C CB  . THR A 1 118 ? 152.768 165.793 157.594 1.00 55.46 ? 146 THR A CB  1 
ATOM   864  O OG1 . THR A 1 118 ? 152.136 164.767 156.818 1.00 55.46 ? 146 THR A OG1 1 
ATOM   865  C CG2 . THR A 1 118 ? 151.704 166.692 158.208 1.00 55.46 ? 146 THR A CG2 1 
ATOM   866  N N   . LYS A 1 119 ? 155.430 164.896 156.747 1.00 51.19 ? 147 LYS A N   1 
ATOM   867  C CA  . LYS A 1 119 ? 156.417 163.989 156.171 1.00 51.19 ? 147 LYS A CA  1 
ATOM   868  C C   . LYS A 1 119 ? 155.760 162.939 155.282 1.00 51.19 ? 147 LYS A C   1 
ATOM   869  O O   . LYS A 1 119 ? 156.280 162.605 154.207 1.00 51.19 ? 147 LYS A O   1 
ATOM   870  C CB  . LYS A 1 119 ? 157.213 163.322 157.290 1.00 51.19 ? 147 LYS A CB  1 
ATOM   871  C CG  . LYS A 1 119 ? 158.418 162.541 156.823 1.00 51.19 ? 147 LYS A CG  1 
ATOM   872  C CD  . LYS A 1 119 ? 159.155 161.922 157.998 1.00 51.19 ? 147 LYS A CD  1 
ATOM   873  C CE  . LYS A 1 119 ? 159.677 162.991 158.943 1.00 51.19 ? 147 LYS A CE  1 
ATOM   874  N NZ  . LYS A 1 119 ? 160.690 163.867 158.295 1.00 51.19 ? 147 LYS A NZ  1 
ATOM   875  N N   . ASN A 1 120 ? 154.618 162.404 155.718 1.00 53.49 ? 148 ASN A N   1 
ATOM   876  C CA  . ASN A 1 120 ? 153.927 161.389 154.932 1.00 53.49 ? 148 ASN A CA  1 
ATOM   877  C C   . ASN A 1 120 ? 153.515 161.934 153.572 1.00 53.49 ? 148 ASN A C   1 
ATOM   878  O O   . ASN A 1 120 ? 153.623 161.236 152.558 1.00 53.49 ? 148 ASN A O   1 
ATOM   879  C CB  . ASN A 1 120 ? 152.707 160.873 155.692 1.00 53.49 ? 148 ASN A CB  1 
ATOM   880  C CG  . ASN A 1 120 ? 151.773 160.068 154.813 1.00 53.49 ? 148 ASN A CG  1 
ATOM   881  O OD1 . ASN A 1 120 ? 152.052 158.916 154.483 1.00 53.49 ? 148 ASN A OD1 1 
ATOM   882  N ND2 . ASN A 1 120 ? 150.657 160.673 154.423 1.00 53.49 ? 148 ASN A ND2 1 
ATOM   883  N N   . LYS A 1 121 ? 153.036 163.179 153.531 1.00 51.21 ? 149 LYS A N   1 
ATOM   884  C CA  . LYS A 1 121 ? 152.669 163.780 152.253 1.00 51.21 ? 149 LYS A CA  1 
ATOM   885  C C   . LYS A 1 121 ? 153.886 163.935 151.349 1.00 51.21 ? 149 LYS A C   1 
ATOM   886  O O   . LYS A 1 121 ? 153.793 163.739 150.131 1.00 51.21 ? 149 LYS A O   1 
ATOM   887  C CB  . LYS A 1 121 ? 151.988 165.127 152.484 1.00 51.21 ? 149 LYS A CB  1 
ATOM   888  C CG  . LYS A 1 121 ? 150.758 165.049 153.374 1.00 51.21 ? 149 LYS A CG  1 
ATOM   889  C CD  . LYS A 1 121 ? 149.798 163.961 152.910 1.00 51.21 ? 149 LYS A CD  1 
ATOM   890  C CE  . LYS A 1 121 ? 149.181 164.290 151.558 1.00 51.21 ? 149 LYS A CE  1 
ATOM   891  N NZ  . LYS A 1 121 ? 148.257 163.219 151.094 1.00 51.21 ? 149 LYS A NZ  1 
ATOM   892  N N   . ALA A 1 122 ? 155.037 164.286 151.928 1.00 47.49 ? 150 ALA A N   1 
ATOM   893  C CA  . ALA A 1 122 ? 156.261 164.392 151.141 1.00 47.49 ? 150 ALA A CA  1 
ATOM   894  C C   . ALA A 1 122 ? 156.624 163.054 150.516 1.00 47.49 ? 150 ALA A C   1 
ATOM   895  O O   . ALA A 1 122 ? 156.922 162.974 149.317 1.00 47.49 ? 150 ALA A O   1 
ATOM   896  C CB  . ALA A 1 122 ? 157.405 164.900 152.015 1.00 47.49 ? 150 ALA A CB  1 
ATOM   897  N N   . ARG A 1 123 ? 156.591 161.984 151.314 1.00 48.18 ? 151 ARG A N   1 
ATOM   898  C CA  . ARG A 1 123 ? 156.900 160.663 150.773 1.00 48.18 ? 151 ARG A CA  1 
ATOM   899  C C   . ARG A 1 123 ? 155.899 160.264 149.696 1.00 48.18 ? 151 ARG A C   1 
ATOM   900  O O   . ARG A 1 123 ? 156.279 159.708 148.657 1.00 48.18 ? 151 ARG A O   1 
ATOM   901  C CB  . ARG A 1 123 ? 156.925 159.622 151.890 1.00 48.18 ? 151 ARG A CB  1 
ATOM   902  C CG  . ARG A 1 123 ? 157.238 158.218 151.406 1.00 48.18 ? 151 ARG A CG  1 
ATOM   903  C CD  . ARG A 1 123 ? 156.487 157.169 152.213 1.00 48.18 ? 151 ARG A CD  1 
ATOM   904  N NE  . ARG A 1 123 ? 157.131 156.885 153.493 1.00 48.18 ? 151 ARG A NE  1 
ATOM   905  C CZ  . ARG A 1 123 ? 157.824 155.782 153.753 1.00 48.18 ? 151 ARG A CZ  1 
ATOM   906  N NH1 . ARG A 1 123 ? 157.967 154.848 152.822 1.00 48.18 ? 151 ARG A NH1 1 
ATOM   907  N NH2 . ARG A 1 123 ? 158.375 155.610 154.946 1.00 48.18 ? 151 ARG A NH2 1 
ATOM   908  N N   . VAL A 1 124 ? 154.616 160.556 149.921 1.00 46.16 ? 152 VAL A N   1 
ATOM   909  C CA  . VAL A 1 124 ? 153.585 160.180 148.960 1.00 46.16 ? 152 VAL A CA  1 
ATOM   910  C C   . VAL A 1 124 ? 153.808 160.888 147.631 1.00 46.16 ? 152 VAL A C   1 
ATOM   911  O O   . VAL A 1 124 ? 153.761 160.266 146.564 1.00 46.16 ? 152 VAL A O   1 
ATOM   912  C CB  . VAL A 1 124 ? 152.187 160.478 149.528 1.00 46.16 ? 152 VAL A CB  1 
ATOM   913  C CG1 . VAL A 1 124 ? 151.158 160.513 148.412 1.00 46.16 ? 152 VAL A CG1 1 
ATOM   914  C CG2 . VAL A 1 124 ? 151.812 159.440 150.569 1.00 46.16 ? 152 VAL A CG2 1 
ATOM   915  N N   . ILE A 1 125 ? 154.063 162.198 147.671 1.00 39.25 ? 153 ILE A N   1 
ATOM   916  C CA  . ILE A 1 125 ? 154.219 162.946 146.426 1.00 39.25 ? 153 ILE A CA  1 
ATOM   917  C C   . ILE A 1 125 ? 155.507 162.547 145.712 1.00 39.25 ? 153 ILE A C   1 
ATOM   918  O O   . ILE A 1 125 ? 155.543 162.461 144.477 1.00 39.25 ? 153 ILE A O   1 
ATOM   919  C CB  . ILE A 1 125 ? 154.139 164.463 146.682 1.00 39.25 ? 153 ILE A CB  1 
ATOM   920  C CG1 . ILE A 1 125 ? 153.939 165.209 145.363 1.00 39.25 ? 153 ILE A CG1 1 
ATOM   921  C CG2 . ILE A 1 125 ? 155.366 164.978 147.403 1.00 39.25 ? 153 ILE A CG2 1 
ATOM   922  C CD1 . ILE A 1 125 ? 152.504 165.234 144.893 1.00 39.25 ? 153 ILE A CD1 1 
ATOM   923  N N   . ILE A 1 126 ? 156.579 162.280 146.468 1.00 34.66 ? 154 ILE A N   1 
ATOM   924  C CA  . ILE A 1 126 ? 157.827 161.851 145.844 1.00 34.66 ? 154 ILE A CA  1 
ATOM   925  C C   . ILE A 1 126 ? 157.627 160.527 145.120 1.00 34.66 ? 154 ILE A C   1 
ATOM   926  O O   . ILE A 1 126 ? 158.023 160.366 143.958 1.00 34.66 ? 154 ILE A O   1 
ATOM   927  C CB  . ILE A 1 126 ? 158.950 161.761 146.891 1.00 34.66 ? 154 ILE A CB  1 
ATOM   928  C CG1 . ILE A 1 126 ? 159.528 163.146 147.167 1.00 34.66 ? 154 ILE A CG1 1 
ATOM   929  C CG2 . ILE A 1 126 ? 160.041 160.825 146.427 1.00 34.66 ? 154 ILE A CG2 1 
ATOM   930  C CD1 . ILE A 1 126 ? 160.547 163.164 148.274 1.00 34.66 ? 154 ILE A CD1 1 
ATOM   931  N N   . LEU A 1 127 ? 156.990 159.563 145.787 1.00 38.24 ? 155 LEU A N   1 
ATOM   932  C CA  . LEU A 1 127 ? 156.759 158.277 145.142 1.00 38.24 ? 155 LEU A CA  1 
ATOM   933  C C   . LEU A 1 127 ? 155.820 158.420 143.952 1.00 38.24 ? 155 LEU A C   1 
ATOM   934  O O   . LEU A 1 127 ? 155.997 157.748 142.931 1.00 38.24 ? 155 LEU A O   1 
ATOM   935  C CB  . LEU A 1 127 ? 156.214 157.270 146.151 1.00 38.24 ? 155 LEU A CB  1 
ATOM   936  C CG  . LEU A 1 127 ? 157.239 156.769 147.172 1.00 38.24 ? 155 LEU A CG  1 
ATOM   937  C CD1 . LEU A 1 127 ? 156.681 155.599 147.967 1.00 38.24 ? 155 LEU A CD1 1 
ATOM   938  C CD2 . LEU A 1 127 ? 158.547 156.389 146.488 1.00 38.24 ? 155 LEU A CD2 1 
ATOM   939  N N   . MET A 1 128 ? 154.823 159.300 144.058 1.00 37.64 ? 156 MET A N   1 
ATOM   940  C CA  . MET A 1 128 ? 153.896 159.503 142.951 1.00 37.64 ? 156 MET A CA  1 
ATOM   941  C C   . MET A 1 128 ? 154.621 160.017 141.714 1.00 37.64 ? 156 MET A C   1 
ATOM   942  O O   . MET A 1 128 ? 154.447 159.485 140.609 1.00 37.64 ? 156 MET A O   1 
ATOM   943  C CB  . MET A 1 128 ? 152.793 160.476 143.369 1.00 37.64 ? 156 MET A CB  1 
ATOM   944  C CG  . MET A 1 128 ? 151.425 160.156 142.794 1.00 37.64 ? 156 MET A CG  1 
ATOM   945  S SD  . MET A 1 128 ? 150.230 161.472 143.096 1.00 37.64 ? 156 MET A SD  1 
ATOM   946  C CE  . MET A 1 128 ? 150.461 161.748 144.850 1.00 37.64 ? 156 MET A CE  1 
ATOM   947  N N   . VAL A 1 129 ? 155.450 161.051 141.879 1.00 34.01 ? 157 VAL A N   1 
ATOM   948  C CA  . VAL A 1 129 ? 156.135 161.615 140.720 1.00 34.01 ? 157 VAL A CA  1 
ATOM   949  C C   . VAL A 1 129 ? 157.150 160.623 140.163 1.00 34.01 ? 157 VAL A C   1 
ATOM   950  O O   . VAL A 1 129 ? 157.303 160.491 138.939 1.00 34.01 ? 157 VAL A O   1 
ATOM   951  C CB  . VAL A 1 129 ? 156.780 162.969 141.068 1.00 34.01 ? 157 VAL A CB  1 
ATOM   952  C CG1 . VAL A 1 129 ? 157.963 162.808 142.005 1.00 34.01 ? 157 VAL A CG1 1 
ATOM   953  C CG2 . VAL A 1 129 ? 157.206 163.664 139.811 1.00 34.01 ? 157 VAL A CG2 1 
ATOM   954  N N   . TRP A 1 130 ? 157.839 159.891 141.045 1.00 23.43 ? 158 TRP A N   1 
ATOM   955  C CA  . TRP A 1 130 ? 158.810 158.910 140.581 1.00 23.43 ? 158 TRP A CA  1 
ATOM   956  C C   . TRP A 1 130 ? 158.138 157.814 139.771 1.00 23.43 ? 158 TRP A C   1 
ATOM   957  O O   . TRP A 1 130 ? 158.648 157.412 138.723 1.00 23.43 ? 158 TRP A O   1 
ATOM   958  C CB  . TRP A 1 130 ? 159.557 158.311 141.766 1.00 23.43 ? 158 TRP A CB  1 
ATOM   959  C CG  . TRP A 1 130 ? 160.919 158.867 141.957 1.00 23.43 ? 158 TRP A CG  1 
ATOM   960  C CD1 . TRP A 1 130 ? 161.272 159.901 142.769 1.00 23.43 ? 158 TRP A CD1 1 
ATOM   961  C CD2 . TRP A 1 130 ? 162.123 158.416 141.333 1.00 23.43 ? 158 TRP A CD2 1 
ATOM   962  N NE1 . TRP A 1 130 ? 162.623 160.124 142.690 1.00 23.43 ? 158 TRP A NE1 1 
ATOM   963  C CE2 . TRP A 1 130 ? 163.168 159.224 141.813 1.00 23.43 ? 158 TRP A CE2 1 
ATOM   964  C CE3 . TRP A 1 130 ? 162.419 157.408 140.413 1.00 23.43 ? 158 TRP A CE3 1 
ATOM   965  C CZ2 . TRP A 1 130 ? 164.485 159.056 141.406 1.00 23.43 ? 158 TRP A CZ2 1 
ATOM   966  C CZ3 . TRP A 1 130 ? 163.729 157.244 140.012 1.00 23.43 ? 158 TRP A CZ3 1 
ATOM   967  C CH2 . TRP A 1 130 ? 164.744 158.064 140.505 1.00 23.43 ? 158 TRP A CH2 1 
ATOM   968  N N   . ILE A 1 131 ? 156.982 157.327 140.229 1.00 31.76 ? 159 ILE A N   1 
ATOM   969  C CA  . ILE A 1 131 ? 156.323 156.251 139.499 1.00 31.76 ? 159 ILE A CA  1 
ATOM   970  C C   . ILE A 1 131 ? 155.706 156.762 138.204 1.00 31.76 ? 159 ILE A C   1 
ATOM   971  O O   . ILE A 1 131 ? 155.662 156.030 137.211 1.00 31.76 ? 159 ILE A O   1 
ATOM   972  C CB  . ILE A 1 131 ? 155.283 155.533 140.378 1.00 31.76 ? 159 ILE A CB  1 
ATOM   973  C CG1 . ILE A 1 131 ? 154.936 154.178 139.761 1.00 31.76 ? 159 ILE A CG1 1 
ATOM   974  C CG2 . ILE A 1 131 ? 154.024 156.367 140.547 1.00 31.76 ? 159 ILE A CG2 1 
ATOM   975  C CD1 . ILE A 1 131 ? 156.126 153.250 139.627 1.00 31.76 ? 159 ILE A CD1 1 
ATOM   976  N N   . VAL A 1 132 ? 155.230 158.010 138.171 1.00 28.55 ? 160 VAL A N   1 
ATOM   977  C CA  . VAL A 1 132 ? 154.701 158.547 136.919 1.00 28.55 ? 160 VAL A CA  1 
ATOM   978  C C   . VAL A 1 132 ? 155.808 158.650 135.875 1.00 28.55 ? 160 VAL A C   1 
ATOM   979  O O   . VAL A 1 132 ? 155.646 158.219 134.723 1.00 28.55 ? 160 VAL A O   1 
ATOM   980  C CB  . VAL A 1 132 ? 154.021 159.905 137.156 1.00 28.55 ? 160 VAL A CB  1 
ATOM   981  C CG1 . VAL A 1 132 ? 153.835 160.631 135.836 1.00 28.55 ? 160 VAL A CG1 1 
ATOM   982  C CG2 . VAL A 1 132 ? 152.690 159.707 137.850 1.00 28.55 ? 160 VAL A CG2 1 
ATOM   983  N N   . SER A 1 133 ? 156.961 159.201 136.267 1.00 27.66 ? 161 SER A N   1 
ATOM   984  C CA  . SER A 1 133 ? 158.085 159.272 135.338 1.00 27.66 ? 161 SER A CA  1 
ATOM   985  C C   . SER A 1 133 ? 158.559 157.880 134.936 1.00 27.66 ? 161 SER A C   1 
ATOM   986  O O   . SER A 1 133 ? 158.883 157.639 133.767 1.00 27.66 ? 161 SER A O   1 
ATOM   987  C CB  . SER A 1 133 ? 159.229 160.066 135.960 1.00 27.66 ? 161 SER A CB  1 
ATOM   988  O OG  . SER A 1 133 ? 160.046 159.225 136.750 1.00 27.66 ? 161 SER A OG  1 
ATOM   989  N N   . GLY A 1 134 ? 158.608 156.951 135.891 1.00 26.28 ? 162 GLY A N   1 
ATOM   990  C CA  . GLY A 1 134 ? 159.061 155.606 135.584 1.00 26.28 ? 162 GLY A CA  1 
ATOM   991  C C   . GLY A 1 134 ? 158.151 154.885 134.612 1.00 26.28 ? 162 GLY A C   1 
ATOM   992  O O   . GLY A 1 134 ? 158.617 154.153 133.739 1.00 26.28 ? 162 GLY A O   1 
ATOM   993  N N   . LEU A 1 135 ? 156.840 155.060 134.764 1.00 33.43 ? 163 LEU A N   1 
ATOM   994  C CA  . LEU A 1 135 ? 155.912 154.510 133.786 1.00 33.43 ? 163 LEU A CA  1 
ATOM   995  C C   . LEU A 1 135 ? 156.138 155.143 132.422 1.00 33.43 ? 163 LEU A C   1 
ATOM   996  O O   . LEU A 1 135 ? 156.252 154.440 131.409 1.00 33.43 ? 163 LEU A O   1 
ATOM   997  C CB  . LEU A 1 135 ? 154.474 154.725 134.250 1.00 33.43 ? 163 LEU A CB  1 
ATOM   998  C CG  . LEU A 1 135 ? 153.415 154.477 133.181 1.00 33.43 ? 163 LEU A CG  1 
ATOM   999  C CD1 . LEU A 1 135 ? 153.331 152.992 132.872 1.00 33.43 ? 163 LEU A CD1 1 
ATOM   1000 C CD2 . LEU A 1 135 ? 152.066 155.022 133.621 1.00 33.43 ? 163 LEU A CD2 1 
ATOM   1001 N N   . THR A 1 136 ? 156.253 156.476 132.384 1.00 29.56 ? 164 THR A N   1 
ATOM   1002 C CA  . THR A 1 136 ? 156.439 157.167 131.111 1.00 29.56 ? 164 THR A CA  1 
ATOM   1003 C C   . THR A 1 136 ? 157.726 156.734 130.414 1.00 29.56 ? 164 THR A C   1 
ATOM   1004 O O   . THR A 1 136 ? 157.815 156.788 129.182 1.00 29.56 ? 164 THR A O   1 
ATOM   1005 C CB  . THR A 1 136 ? 156.434 158.677 131.342 1.00 29.56 ? 164 THR A CB  1 
ATOM   1006 O OG1 . THR A 1 136 ? 155.206 159.052 131.975 1.00 29.56 ? 164 THR A OG1 1 
ATOM   1007 C CG2 . THR A 1 136 ? 156.544 159.426 130.027 1.00 29.56 ? 164 THR A CG2 1 
ATOM   1008 N N   . SER A 1 137 ? 158.726 156.291 131.175 1.00 29.37 ? 165 SER A N   1 
ATOM   1009 C CA  . SER A 1 137 ? 159.989 155.875 130.574 1.00 29.37 ? 165 SER A CA  1 
ATOM   1010 C C   . SER A 1 137 ? 160.024 154.391 130.208 1.00 29.37 ? 165 SER A C   1 
ATOM   1011 O O   . SER A 1 137 ? 160.447 154.042 129.103 1.00 29.37 ? 165 SER A O   1 
ATOM   1012 C CB  . SER A 1 137 ? 161.146 156.213 131.510 1.00 29.37 ? 165 SER A CB  1 
ATOM   1013 O OG  . SER A 1 137 ? 161.252 157.613 131.673 1.00 29.37 ? 165 SER A OG  1 
ATOM   1014 N N   . PHE A 1 138 ? 159.612 153.503 131.116 1.00 33.08 ? 166 PHE A N   1 
ATOM   1015 C CA  . PHE A 1 138 ? 159.580 152.079 130.789 1.00 33.08 ? 166 PHE A CA  1 
ATOM   1016 C C   . PHE A 1 138 ? 158.590 151.768 129.673 1.00 33.08 ? 166 PHE A C   1 
ATOM   1017 O O   . PHE A 1 138 ? 158.946 151.110 128.690 1.00 33.08 ? 166 PHE A O   1 
ATOM   1018 C CB  . PHE A 1 138 ? 159.249 151.237 132.024 1.00 33.08 ? 166 PHE A CB  1 
ATOM   1019 C CG  . PHE A 1 138 ? 160.327 151.209 133.067 1.00 33.08 ? 166 PHE A CG  1 
ATOM   1020 C CD1 . PHE A 1 138 ? 161.605 151.634 132.778 1.00 33.08 ? 166 PHE A CD1 1 
ATOM   1021 C CD2 . PHE A 1 138 ? 160.070 150.701 134.330 1.00 33.08 ? 166 PHE A CD2 1 
ATOM   1022 C CE1 . PHE A 1 138 ? 162.605 151.580 133.728 1.00 33.08 ? 166 PHE A CE1 1 
ATOM   1023 C CE2 . PHE A 1 138 ? 161.066 150.646 135.288 1.00 33.08 ? 166 PHE A CE2 1 
ATOM   1024 C CZ  . PHE A 1 138 ? 162.335 151.089 134.984 1.00 33.08 ? 166 PHE A CZ  1 
ATOM   1025 N N   . LEU A 1 139 ? 157.340 152.221 129.807 1.00 42.44 ? 167 LEU A N   1 
ATOM   1026 C CA  . LEU A 1 139 ? 156.268 151.646 128.995 1.00 42.44 ? 167 LEU A CA  1 
ATOM   1027 C C   . LEU A 1 139 ? 156.507 151.760 127.494 1.00 42.44 ? 167 LEU A C   1 
ATOM   1028 O O   . LEU A 1 139 ? 156.391 150.736 126.799 1.00 42.44 ? 167 LEU A O   1 
ATOM   1029 C CB  . LEU A 1 139 ? 154.929 152.273 129.396 1.00 42.44 ? 167 LEU A CB  1 
ATOM   1030 C CG  . LEU A 1 139 ? 153.683 151.508 128.950 1.00 42.44 ? 167 LEU A CG  1 
ATOM   1031 C CD1 . LEU A 1 139 ? 153.460 150.299 129.841 1.00 42.44 ? 167 LEU A CD1 1 
ATOM   1032 C CD2 . LEU A 1 139 ? 152.459 152.413 128.948 1.00 42.44 ? 167 LEU A CD2 1 
ATOM   1033 N N   . PRO A 1 140 ? 156.838 152.923 126.926 1.00 46.26 ? 168 PRO A N   1 
ATOM   1034 C CA  . PRO A 1 140 ? 157.024 152.968 125.468 1.00 46.26 ? 168 PRO A CA  1 
ATOM   1035 C C   . PRO A 1 140 ? 158.273 152.246 124.988 1.00 46.26 ? 168 PRO A C   1 
ATOM   1036 O O   . PRO A 1 140 ? 158.267 151.706 123.875 1.00 46.26 ? 168 PRO A O   1 
ATOM   1037 C CB  . PRO A 1 140 ? 157.086 154.470 125.167 1.00 46.26 ? 168 PRO A CB  1 
ATOM   1038 C CG  . PRO A 1 140 ? 157.543 155.081 126.429 1.00 46.26 ? 168 PRO A CG  1 
ATOM   1039 C CD  . PRO A 1 140 ? 156.951 154.263 127.527 1.00 46.26 ? 168 PRO A CD  1 
ATOM   1040 N N   . ILE A 1 141 ? 159.341 152.219 125.789 1.00 46.00 ? 169 ILE A N   1 
ATOM   1041 C CA  . ILE A 1 141 ? 160.604 151.643 125.331 1.00 46.00 ? 169 ILE A CA  1 
ATOM   1042 C C   . ILE A 1 141 ? 160.483 150.133 125.166 1.00 46.00 ? 169 ILE A C   1 
ATOM   1043 O O   . ILE A 1 141 ? 160.868 149.573 124.134 1.00 46.00 ? 169 ILE A O   1 
ATOM   1044 C CB  . ILE A 1 141 ? 161.742 152.007 126.299 1.00 46.00 ? 169 ILE A CB  1 
ATOM   1045 C CG1 . ILE A 1 141 ? 161.958 153.515 126.319 1.00 46.00 ? 169 ILE A CG1 1 
ATOM   1046 C CG2 . ILE A 1 141 ? 163.016 151.303 125.899 1.00 46.00 ? 169 ILE A CG2 1 
ATOM   1047 C CD1 . ILE A 1 141 ? 162.244 154.084 124.967 1.00 46.00 ? 169 ILE A CD1 1 
ATOM   1048 N N   . GLN A 1 142 ? 159.942 149.453 126.178 1.00 51.35 ? 170 GLN A N   1 
ATOM   1049 C CA  . GLN A 1 142 ? 159.913 147.994 126.150 1.00 51.35 ? 170 GLN A CA  1 
ATOM   1050 C C   . GLN A 1 142 ? 158.919 147.469 125.123 1.00 51.35 ? 170 GLN A C   1 
ATOM   1051 O O   . GLN A 1 142 ? 159.087 146.355 124.615 1.00 51.35 ? 170 GLN A O   1 
ATOM   1052 C CB  . GLN A 1 142 ? 159.579 147.450 127.539 1.00 51.35 ? 170 GLN A CB  1 
ATOM   1053 C CG  . GLN A 1 142 ? 160.508 147.930 128.653 1.00 51.35 ? 170 GLN A CG  1 
ATOM   1054 C CD  . GLN A 1 142 ? 161.831 147.190 128.701 1.00 51.35 ? 170 GLN A CD  1 
ATOM   1055 O OE1 . GLN A 1 142 ? 162.427 146.887 127.670 1.00 51.35 ? 170 GLN A OE1 1 
ATOM   1056 N NE2 . GLN A 1 142 ? 162.300 146.902 129.908 1.00 51.35 ? 170 GLN A NE2 1 
ATOM   1057 N N   . MET A 1 143 ? 157.889 148.249 124.805 1.00 61.55 ? 171 MET A N   1 
ATOM   1058 C CA  . MET A 1 143 ? 156.857 147.848 123.859 1.00 61.55 ? 171 MET A CA  1 
ATOM   1059 C C   . MET A 1 143 ? 157.241 148.174 122.416 1.00 61.55 ? 171 MET A C   1 
ATOM   1060 O O   . MET A 1 143 ? 156.492 147.844 121.490 1.00 61.55 ? 171 MET A O   1 
ATOM   1061 C CB  . MET A 1 143 ? 155.527 148.510 124.248 1.00 61.55 ? 171 MET A CB  1 
ATOM   1062 C CG  . MET A 1 143 ? 154.310 148.097 123.436 1.00 61.55 ? 171 MET A CG  1 
ATOM   1063 S SD  . MET A 1 143 ? 152.811 148.926 123.992 1.00 61.55 ? 171 MET A SD  1 
ATOM   1064 C CE  . MET A 1 143 ? 152.527 148.096 125.552 1.00 61.55 ? 171 MET A CE  1 
ATOM   1065 N N   . HIS A 1 144 ? 158.404 148.795 122.211 1.00 67.56 ? 172 HIS A N   1 
ATOM   1066 C CA  . HIS A 1 144 ? 158.977 149.027 120.885 1.00 67.56 ? 172 HIS A CA  1 
ATOM   1067 C C   . HIS A 1 144 ? 158.094 149.956 120.050 1.00 67.56 ? 172 HIS A C   1 
ATOM   1068 O O   . HIS A 1 144 ? 157.634 149.613 118.960 1.00 67.56 ? 172 HIS A O   1 
ATOM   1069 C CB  . HIS A 1 144 ? 159.221 147.700 120.159 1.00 67.56 ? 172 HIS A CB  1 
ATOM   1070 N N   . TRP A 1 145 ? 157.859 151.151 120.590 1.00 69.80 ? 173 TRP A N   1 
ATOM   1071 C CA  . TRP A 1 145 ? 157.160 152.199 119.859 1.00 69.80 ? 173 TRP A CA  1 
ATOM   1072 C C   . TRP A 1 145 ? 158.089 153.099 119.057 1.00 69.80 ? 173 TRP A C   1 
ATOM   1073 O O   . TRP A 1 145 ? 157.600 153.934 118.292 1.00 69.80 ? 173 TRP A O   1 
ATOM   1074 C CB  . TRP A 1 145 ? 156.344 153.076 120.818 1.00 69.80 ? 173 TRP A CB  1 
ATOM   1075 C CG  . TRP A 1 145 ? 155.174 152.403 121.474 1.00 69.80 ? 173 TRP A CG  1 
ATOM   1076 C CD1 . TRP A 1 145 ? 155.136 151.846 122.720 1.00 69.80 ? 173 TRP A CD1 1 
ATOM   1077 C CD2 . TRP A 1 145 ? 153.857 152.251 120.927 1.00 69.80 ? 173 TRP A CD2 1 
ATOM   1078 N NE1 . TRP A 1 145 ? 153.882 151.344 122.975 1.00 69.80 ? 173 TRP A NE1 1 
ATOM   1079 C CE2 . TRP A 1 145 ? 153.079 151.581 121.890 1.00 69.80 ? 173 TRP A CE2 1 
ATOM   1080 C CE3 . TRP A 1 145 ? 153.265 152.611 119.712 1.00 69.80 ? 173 TRP A CE3 1 
ATOM   1081 C CZ2 . TRP A 1 145 ? 151.740 151.261 121.676 1.00 69.80 ? 173 TRP A CZ2 1 
ATOM   1082 C CZ3 . TRP A 1 145 ? 151.935 152.293 119.502 1.00 69.80 ? 173 TRP A CZ3 1 
ATOM   1083 C CH2 . TRP A 1 145 ? 151.188 151.625 120.478 1.00 69.80 ? 173 TRP A CH2 1 
ATOM   1084 N N   . TYR A 1 146 ? 159.406 152.955 119.202 1.00 66.90 ? 174 TYR A N   1 
ATOM   1085 C CA  . TYR A 1 146 ? 160.319 153.960 118.676 1.00 66.90 ? 174 TYR A CA  1 
ATOM   1086 C C   . TYR A 1 146 ? 161.153 153.483 117.495 1.00 66.90 ? 174 TYR A C   1 
ATOM   1087 O O   . TYR A 1 146 ? 161.839 154.305 116.877 1.00 66.90 ? 174 TYR A O   1 
ATOM   1088 C CB  . TYR A 1 146 ? 161.254 154.447 119.786 1.00 66.90 ? 174 TYR A CB  1 
ATOM   1089 C CG  . TYR A 1 146 ? 162.241 153.410 120.267 1.00 66.90 ? 174 TYR A CG  1 
ATOM   1090 C CD1 . TYR A 1 146 ? 161.899 152.506 121.259 1.00 66.90 ? 174 TYR A CD1 1 
ATOM   1091 C CD2 . TYR A 1 146 ? 163.529 153.363 119.756 1.00 66.90 ? 174 TYR A CD2 1 
ATOM   1092 C CE1 . TYR A 1 146 ? 162.800 151.565 121.707 1.00 66.90 ? 174 TYR A CE1 1 
ATOM   1093 C CE2 . TYR A 1 146 ? 164.437 152.429 120.199 1.00 66.90 ? 174 TYR A CE2 1 
ATOM   1094 C CZ  . TYR A 1 146 ? 164.069 151.533 121.175 1.00 66.90 ? 174 TYR A CZ  1 
ATOM   1095 O OH  . TYR A 1 146 ? 164.974 150.598 121.620 1.00 66.90 ? 174 TYR A OH  1 
ATOM   1096 N N   . ARG A 1 147 ? 161.020 152.199 117.130 1.00 71.95 ? 175 ARG A N   1 
ATOM   1097 C CA  . ARG A 1 147 ? 161.884 151.662 116.034 1.00 71.95 ? 175 ARG A CA  1 
ATOM   1098 C C   . ARG A 1 147 ? 161.305 152.066 114.683 1.00 71.95 ? 175 ARG A C   1 
ATOM   1099 O O   . ARG A 1 147 ? 160.100 151.865 114.466 1.00 71.95 ? 175 ARG A O   1 
ATOM   1100 C CB  . ARG A 1 147 ? 162.343 150.214 116.219 1.00 71.95 ? 175 ARG A CB  1 
ATOM   1101 C CG  . ARG A 1 147 ? 163.853 150.053 116.159 1.00 71.95 ? 175 ARG A CG  1 
ATOM   1102 C CD  . ARG A 1 147 ? 164.235 148.933 117.097 1.00 71.95 ? 175 ARG A CD  1 
ATOM   1103 N NE  . ARG A 1 147 ? 163.202 147.915 117.050 1.00 71.95 ? 175 ARG A NE  1 
ATOM   1104 C CZ  . ARG A 1 147 ? 163.236 146.775 117.721 1.00 71.95 ? 175 ARG A CZ  1 
ATOM   1105 N NH1 . ARG A 1 147 ? 164.263 146.499 118.504 1.00 71.95 ? 175 ARG A NH1 1 
ATOM   1106 N NH2 . ARG A 1 147 ? 162.243 145.914 117.609 1.00 71.95 ? 175 ARG A NH2 1 
ATOM   1107 N N   . ALA A 1 148 ? 162.148 152.634 113.830 1.00 70.42 ? 176 ALA A N   1 
ATOM   1108 C CA  . ALA A 1 148 ? 161.696 153.177 112.559 1.00 70.42 ? 176 ALA A CA  1 
ATOM   1109 C C   . ALA A 1 148 ? 161.731 152.095 111.480 1.00 70.42 ? 176 ALA A C   1 
ATOM   1110 O O   . ALA A 1 148 ? 161.894 150.905 111.761 1.00 70.42 ? 176 ALA A O   1 
ATOM   1111 C CB  . ALA A 1 148 ? 162.545 154.385 112.171 1.00 70.42 ? 176 ALA A CB  1 
ATOM   1112 N N   . THR A 1 149 ? 161.574 152.511 110.222 1.00 74.03 ? 177 THR A N   1 
ATOM   1113 C CA  . THR A 1 149 ? 161.549 151.598 109.087 1.00 74.03 ? 177 THR A CA  1 
ATOM   1114 C C   . THR A 1 149 ? 162.857 151.590 108.303 1.00 74.03 ? 177 THR A C   1 
ATOM   1115 O O   . THR A 1 149 ? 163.063 150.691 107.479 1.00 74.03 ? 177 THR A O   1 
ATOM   1116 C CB  . THR A 1 149 ? 160.388 151.968 108.151 1.00 74.03 ? 177 THR A CB  1 
ATOM   1117 O OG1 . THR A 1 149 ? 159.209 152.200 108.931 1.00 74.03 ? 177 THR A OG1 1 
ATOM   1118 C CG2 . THR A 1 149 ? 160.090 150.843 107.169 1.00 74.03 ? 177 THR A CG2 1 
ATOM   1119 N N   . HIS A 1 150 ? 163.744 152.552 108.554 1.00 74.88 ? 178 HIS A N   1 
ATOM   1120 C CA  . HIS A 1 150 ? 165.006 152.627 107.829 1.00 74.88 ? 178 HIS A CA  1 
ATOM   1121 C C   . HIS A 1 150 ? 165.795 151.336 108.029 1.00 74.88 ? 178 HIS A C   1 
ATOM   1122 O O   . HIS A 1 150 ? 165.920 150.834 109.149 1.00 74.88 ? 178 HIS A O   1 
ATOM   1123 C CB  . HIS A 1 150 ? 165.800 153.840 108.318 1.00 74.88 ? 178 HIS A CB  1 
ATOM   1124 C CG  . HIS A 1 150 ? 167.042 154.120 107.532 1.00 74.88 ? 178 HIS A CG  1 
ATOM   1125 N ND1 . HIS A 1 150 ? 167.302 153.522 106.318 1.00 74.88 ? 178 HIS A ND1 1 
ATOM   1126 C CD2 . HIS A 1 150 ? 168.106 154.914 107.795 1.00 74.88 ? 178 HIS A CD2 1 
ATOM   1127 C CE1 . HIS A 1 150 ? 168.470 153.940 105.864 1.00 74.88 ? 178 HIS A CE1 1 
ATOM   1128 N NE2 . HIS A 1 150 ? 168.976 154.789 106.739 1.00 74.88 ? 178 HIS A NE2 1 
ATOM   1129 N N   . GLN A 1 151 ? 166.322 150.790 106.927 1.00 74.63 ? 179 GLN A N   1 
ATOM   1130 C CA  . GLN A 1 151 ? 166.820 149.416 106.951 1.00 74.63 ? 179 GLN A CA  1 
ATOM   1131 C C   . GLN A 1 151 ? 168.020 149.257 107.879 1.00 74.63 ? 179 GLN A C   1 
ATOM   1132 O O   . GLN A 1 151 ? 168.130 148.250 108.588 1.00 74.63 ? 179 GLN A O   1 
ATOM   1133 C CB  . GLN A 1 151 ? 167.158 148.940 105.535 1.00 74.63 ? 179 GLN A CB  1 
ATOM   1134 N N   . GLU A 1 152 ? 168.932 150.232 107.893 1.00 74.51 ? 180 GLU A N   1 
ATOM   1135 C CA  . GLU A 1 152 ? 170.088 150.112 108.775 1.00 74.51 ? 180 GLU A CA  1 
ATOM   1136 C C   . GLU A 1 152 ? 169.694 150.288 110.235 1.00 74.51 ? 180 GLU A C   1 
ATOM   1137 O O   . GLU A 1 152 ? 170.366 149.756 111.126 1.00 74.51 ? 180 GLU A O   1 
ATOM   1138 C CB  . GLU A 1 152 ? 171.172 151.112 108.375 1.00 74.51 ? 180 GLU A CB  1 
ATOM   1139 N N   . ALA A 1 153 ? 168.606 151.012 110.502 1.00 73.29 ? 181 ALA A N   1 
ATOM   1140 C CA  . ALA A 1 153 ? 168.054 151.022 111.851 1.00 73.29 ? 181 ALA A CA  1 
ATOM   1141 C C   . ALA A 1 153 ? 167.591 149.628 112.252 1.00 73.29 ? 181 ALA A C   1 
ATOM   1142 O O   . ALA A 1 153 ? 167.824 149.188 113.384 1.00 73.29 ? 181 ALA A O   1 
ATOM   1143 C CB  . ALA A 1 153 ? 166.904 152.023 111.946 1.00 73.29 ? 181 ALA A CB  1 
ATOM   1144 N N   . ILE A 1 154 ? 166.947 148.911 111.329 1.00 69.34 ? 182 ILE A N   1 
ATOM   1145 C CA  . ILE A 1 154 ? 166.559 147.529 111.595 1.00 69.34 ? 182 ILE A CA  1 
ATOM   1146 C C   . ILE A 1 154 ? 167.793 146.667 111.816 1.00 69.34 ? 182 ILE A C   1 
ATOM   1147 O O   . ILE A 1 154 ? 167.793 145.758 112.654 1.00 69.34 ? 182 ILE A O   1 
ATOM   1148 C CB  . ILE A 1 154 ? 165.691 146.988 110.445 1.00 69.34 ? 182 ILE A CB  1 
ATOM   1149 C CG1 . ILE A 1 154 ? 164.513 147.926 110.180 1.00 69.34 ? 182 ILE A CG1 1 
ATOM   1150 C CG2 . ILE A 1 154 ? 165.192 145.589 110.765 1.00 69.34 ? 182 ILE A CG2 1 
ATOM   1151 C CD1 . ILE A 1 154 ? 163.785 147.637 108.887 1.00 69.34 ? 182 ILE A CD1 1 
ATOM   1152 N N   . ASN A 1 155 ? 168.861 146.931 111.060 1.00 69.57 ? 183 ASN A N   1 
ATOM   1153 C CA  . ASN A 1 155 ? 170.095 146.172 111.232 1.00 69.57 ? 183 ASN A CA  1 
ATOM   1154 C C   . ASN A 1 155 ? 170.685 146.384 112.621 1.00 69.57 ? 183 ASN A C   1 
ATOM   1155 O O   . ASN A 1 155 ? 171.070 145.422 113.295 1.00 69.57 ? 183 ASN A O   1 
ATOM   1156 C CB  . ASN A 1 155 ? 171.105 146.562 110.155 1.00 69.57 ? 183 ASN A CB  1 
ATOM   1157 N N   . CYS A 1 156 ? 170.759 147.641 113.068 1.00 75.10 ? 184 CYS A N   1 
ATOM   1158 C CA  . CYS A 1 156 ? 171.232 147.916 114.422 1.00 75.10 ? 184 CYS A CA  1 
ATOM   1159 C C   . CYS A 1 156 ? 170.307 147.318 115.472 1.00 75.10 ? 184 CYS A C   1 
ATOM   1160 O O   . CYS A 1 156 ? 170.766 146.920 116.548 1.00 75.10 ? 184 CYS A O   1 
ATOM   1161 C CB  . CYS A 1 156 ? 171.383 149.421 114.644 1.00 75.10 ? 184 CYS A CB  1 
ATOM   1162 S SG  . CYS A 1 156 ? 172.891 150.133 113.952 1.00 75.10 ? 184 CYS A SG  1 
ATOM   1163 N N   . TYR A 1 157 ? 169.005 147.258 115.188 1.00 67.20 ? 185 TYR A N   1 
ATOM   1164 C CA  . TYR A 1 157 ? 168.096 146.562 116.089 1.00 67.20 ? 185 TYR A CA  1 
ATOM   1165 C C   . TYR A 1 157 ? 168.438 145.082 116.183 1.00 67.20 ? 185 TYR A C   1 
ATOM   1166 O O   . TYR A 1 157 ? 168.453 144.516 117.282 1.00 67.20 ? 185 TYR A O   1 
ATOM   1167 C CB  . TYR A 1 157 ? 166.651 146.746 115.623 1.00 67.20 ? 185 TYR A CB  1 
ATOM   1168 N N   . ALA A 1 158 ? 168.723 144.445 115.049 1.00 66.86 ? 186 ALA A N   1 
ATOM   1169 C CA  . ALA A 1 158 ? 169.091 143.036 115.025 1.00 66.86 ? 186 ALA A CA  1 
ATOM   1170 C C   . ALA A 1 158 ? 170.506 142.797 115.534 1.00 66.86 ? 186 ALA A C   1 
ATOM   1171 O O   . ALA A 1 158 ? 170.734 141.859 116.304 1.00 66.86 ? 186 ALA A O   1 
ATOM   1172 C CB  . ALA A 1 158 ? 168.949 142.480 113.606 1.00 66.86 ? 186 ALA A CB  1 
ATOM   1173 N N   . GLU A 1 159 ? 171.459 143.628 115.122 1.00 70.48 ? 187 GLU A N   1 
ATOM   1174 C CA  . GLU A 1 159 ? 172.836 143.462 115.565 1.00 70.48 ? 187 GLU A CA  1 
ATOM   1175 C C   . GLU A 1 159 ? 172.970 143.848 117.032 1.00 70.48 ? 187 GLU A C   1 
ATOM   1176 O O   . GLU A 1 159 ? 172.483 144.900 117.456 1.00 70.48 ? 187 GLU A O   1 
ATOM   1177 C CB  . GLU A 1 159 ? 173.779 144.303 114.707 1.00 70.48 ? 187 GLU A CB  1 
ATOM   1178 N N   . GLU A 1 160 ? 173.638 142.993 117.808 1.00 65.64 ? 188 GLU A N   1 
ATOM   1179 C CA  . GLU A 1 160 ? 173.766 143.244 119.238 1.00 65.64 ? 188 GLU A CA  1 
ATOM   1180 C C   . GLU A 1 160 ? 174.697 144.414 119.530 1.00 65.64 ? 188 GLU A C   1 
ATOM   1181 O O   . GLU A 1 160 ? 174.469 145.158 120.490 1.00 65.64 ? 188 GLU A O   1 
ATOM   1182 C CB  . GLU A 1 160 ? 174.250 141.978 119.948 1.00 65.64 ? 188 GLU A CB  1 
ATOM   1183 N N   . THR A 1 161 ? 175.744 144.594 118.723 1.00 67.73 ? 189 THR A N   1 
ATOM   1184 C CA  . THR A 1 161 ? 176.741 145.616 119.020 1.00 67.73 ? 189 THR A CA  1 
ATOM   1185 C C   . THR A 1 161 ? 176.169 147.024 118.921 1.00 67.73 ? 189 THR A C   1 
ATOM   1186 O O   . THR A 1 161 ? 176.446 147.866 119.783 1.00 67.73 ? 189 THR A O   1 
ATOM   1187 C CB  . THR A 1 161 ? 177.936 145.466 118.080 1.00 67.73 ? 189 THR A CB  1 
ATOM   1188 O OG1 . THR A 1 161 ? 178.487 144.150 118.215 1.00 67.73 ? 189 THR A OG1 1 
ATOM   1189 C CG2 . THR A 1 161 ? 179.006 146.492 118.407 1.00 67.73 ? 189 THR A CG2 1 
ATOM   1190 N N   . CYS A 1 162 ? 175.365 147.297 117.900 1.00 77.82 ? 190 CYS A N   1 
ATOM   1191 C CA  . CYS A 1 162 ? 174.917 148.651 117.610 1.00 77.82 ? 190 CYS A CA  1 
ATOM   1192 C C   . CYS A 1 162 ? 173.780 149.048 118.543 1.00 77.82 ? 190 CYS A C   1 
ATOM   1193 O O   . CYS A 1 162 ? 172.779 148.334 118.655 1.00 77.82 ? 190 CYS A O   1 
ATOM   1194 C CB  . CYS A 1 162 ? 174.470 148.757 116.151 1.00 77.82 ? 190 CYS A CB  1 
ATOM   1195 S SG  . CYS A 1 162 ? 174.077 150.428 115.577 1.00 77.82 ? 190 CYS A SG  1 
ATOM   1196 N N   . CYS A 1 163 ? 173.945 150.189 119.216 1.00 74.13 ? 191 CYS A N   1 
ATOM   1197 C CA  . CYS A 1 163 ? 172.864 150.823 119.959 1.00 74.13 ? 191 CYS A CA  1 
ATOM   1198 C C   . CYS A 1 163 ? 172.675 152.302 119.671 1.00 74.13 ? 191 CYS A C   1 
ATOM   1199 O O   . CYS A 1 163 ? 172.151 153.008 120.539 1.00 74.13 ? 191 CYS A O   1 
ATOM   1200 C CB  . CYS A 1 163 ? 173.045 150.659 121.475 1.00 74.13 ? 191 CYS A CB  1 
ATOM   1201 S SG  . CYS A 1 163 ? 172.780 149.029 122.149 1.00 74.13 ? 191 CYS A SG  1 
ATOM   1202 N N   . ASP A 1 164 ? 173.085 152.799 118.510 1.00 77.58 ? 192 ASP A N   1 
ATOM   1203 C CA  . ASP A 1 164 ? 172.784 154.179 118.167 1.00 77.58 ? 192 ASP A CA  1 
ATOM   1204 C C   . ASP A 1 164 ? 171.276 154.392 118.206 1.00 77.58 ? 192 ASP A C   1 
ATOM   1205 O O   . ASP A 1 164 ? 170.528 153.783 117.437 1.00 77.58 ? 192 ASP A O   1 
ATOM   1206 C CB  . ASP A 1 164 ? 173.348 154.516 116.789 1.00 77.58 ? 192 ASP A CB  1 
ATOM   1207 N N   . PHE A 1 165 ? 170.812 155.136 119.214 1.00 69.44 ? 193 PHE A N   1 
ATOM   1208 C CA  . PHE A 1 165 ? 169.359 155.392 119.353 1.00 69.44 ? 193 PHE A CA  1 
ATOM   1209 C C   . PHE A 1 165 ? 168.829 155.859 118.022 1.00 69.44 ? 193 PHE A C   1 
ATOM   1210 O O   . PHE A 1 165 ? 169.422 156.714 117.370 1.00 69.44 ? 193 PHE A O   1 
ATOM   1211 C CB  . PHE A 1 165 ? 169.043 156.552 120.292 1.00 69.44 ? 193 PHE A CB  1 
ATOM   1212 C CG  . PHE A 1 165 ? 167.854 156.369 121.202 1.00 69.44 ? 193 PHE A CG  1 
ATOM   1213 C CD1 . PHE A 1 165 ? 167.057 155.241 121.127 1.00 69.44 ? 193 PHE A CD1 1 
ATOM   1214 C CD2 . PHE A 1 165 ? 167.541 157.332 122.146 1.00 69.44 ? 193 PHE A CD2 1 
ATOM   1215 C CE1 . PHE A 1 165 ? 165.974 155.082 121.976 1.00 69.44 ? 193 PHE A CE1 1 
ATOM   1216 C CE2 . PHE A 1 165 ? 166.457 157.173 122.992 1.00 69.44 ? 193 PHE A CE2 1 
ATOM   1217 C CZ  . PHE A 1 165 ? 165.675 156.049 122.902 1.00 69.44 ? 193 PHE A CZ  1 
ATOM   1218 N N   . PHE A 1 166 ? 167.708 155.310 117.660 1.00 72.24 ? 194 PHE A N   1 
ATOM   1219 C CA  . PHE A 1 166 ? 167.036 155.693 116.424 1.00 72.24 ? 194 PHE A CA  1 
ATOM   1220 C C   . PHE A 1 166 ? 165.565 155.961 116.716 1.00 72.24 ? 194 PHE A C   1 
ATOM   1221 O O   . PHE A 1 166 ? 164.857 155.091 117.235 1.00 72.24 ? 194 PHE A O   1 
ATOM   1222 C CB  . PHE A 1 166 ? 167.203 154.617 115.356 1.00 72.24 ? 194 PHE A CB  1 
ATOM   1223 C CG  . PHE A 1 166 ? 168.330 154.888 114.405 1.00 72.24 ? 194 PHE A CG  1 
ATOM   1224 C CD1 . PHE A 1 166 ? 168.169 155.782 113.359 1.00 72.24 ? 194 PHE A CD1 1 
ATOM   1225 C CD2 . PHE A 1 166 ? 169.552 154.259 114.560 1.00 72.24 ? 194 PHE A CD2 1 
ATOM   1226 C CE1 . PHE A 1 166 ? 169.204 156.040 112.485 1.00 72.24 ? 194 PHE A CE1 1 
ATOM   1227 C CE2 . PHE A 1 166 ? 170.591 154.512 113.689 1.00 72.24 ? 194 PHE A CE2 1 
ATOM   1228 C CZ  . PHE A 1 166 ? 170.417 155.404 112.651 1.00 72.24 ? 194 PHE A CZ  1 
ATOM   1229 N N   . THR A 1 167 ? 165.115 157.163 116.375 1.00 62.94 ? 195 THR A N   1 
ATOM   1230 C CA  . THR A 1 167 ? 163.751 157.595 116.614 1.00 62.94 ? 195 THR A CA  1 
ATOM   1231 C C   . THR A 1 167 ? 162.803 156.987 115.584 1.00 62.94 ? 195 THR A C   1 
ATOM   1232 O O   . THR A 1 167 ? 163.218 156.406 114.579 1.00 62.94 ? 195 THR A O   1 
ATOM   1233 C CB  . THR A 1 167 ? 163.666 159.117 116.565 1.00 62.94 ? 195 THR A CB  1 
ATOM   1234 O OG1 . THR A 1 167 ? 164.016 159.569 115.252 1.00 62.94 ? 195 THR A OG1 1 
ATOM   1235 C CG2 . THR A 1 167 ? 164.632 159.728 117.566 1.00 62.94 ? 195 THR A CG2 1 
ATOM   1236 N N   . ASN A 1 168 ? 161.505 157.125 115.851 1.00 59.10 ? 196 ASN A N   1 
ATOM   1237 C CA  . ASN A 1 168 ? 160.458 156.724 114.922 1.00 59.10 ? 196 ASN A CA  1 
ATOM   1238 C C   . ASN A 1 168 ? 159.829 157.945 114.250 1.00 59.10 ? 196 ASN A C   1 
ATOM   1239 O O   . ASN A 1 168 ? 158.707 157.867 113.740 1.00 59.10 ? 196 ASN A O   1 
ATOM   1240 C CB  . ASN A 1 168 ? 159.406 155.893 115.667 1.00 59.10 ? 196 ASN A CB  1 
ATOM   1241 C CG  . ASN A 1 168 ? 158.386 155.230 114.744 1.00 59.10 ? 196 ASN A CG  1 
ATOM   1242 O OD1 . ASN A 1 168 ? 158.421 155.384 113.524 1.00 59.10 ? 196 ASN A OD1 1 
ATOM   1243 N ND2 . ASN A 1 168 ? 157.464 154.485 115.340 1.00 59.10 ? 196 ASN A ND2 1 
ATOM   1244 N N   . GLN A 1 169 ? 160.512 159.093 114.304 1.00 52.12 ? 197 GLN A N   1 
ATOM   1245 C CA  . GLN A 1 169 ? 160.053 160.352 113.721 1.00 52.12 ? 197 GLN A CA  1 
ATOM   1246 C C   . GLN A 1 169 ? 158.830 160.878 114.470 1.00 52.12 ? 197 GLN A C   1 
ATOM   1247 O O   . GLN A 1 169 ? 158.373 162.000 114.230 1.00 52.12 ? 197 GLN A O   1 
ATOM   1248 C CB  . GLN A 1 169 ? 159.765 160.174 112.223 1.00 52.12 ? 197 GLN A CB  1 
ATOM   1249 C CG  . GLN A 1 169 ? 159.395 161.440 111.465 1.00 52.12 ? 197 GLN A CG  1 
ATOM   1250 C CD  . GLN A 1 169 ? 160.354 162.583 111.722 1.00 52.12 ? 197 GLN A CD  1 
ATOM   1251 O OE1 . GLN A 1 169 ? 159.936 163.721 111.935 1.00 52.12 ? 197 GLN A OE1 1 
ATOM   1252 N NE2 . GLN A 1 169 ? 161.649 162.291 111.687 1.00 52.12 ? 197 GLN A NE2 1 
ATOM   1253 N N   . ALA A 1 170 ? 158.324 160.093 115.405 1.00 47.91 ? 198 ALA A N   1 
ATOM   1254 C CA  . ALA A 1 170 ? 157.193 160.445 116.253 1.00 47.91 ? 198 ALA A CA  1 
ATOM   1255 C C   . ALA A 1 170 ? 157.496 160.255 117.727 1.00 47.91 ? 198 ALA A C   1 
ATOM   1256 O O   . ALA A 1 170 ? 156.965 160.995 118.556 1.00 47.91 ? 198 ALA A O   1 
ATOM   1257 C CB  . ALA A 1 170 ? 155.958 159.619 115.869 1.00 47.91 ? 198 ALA A CB  1 
ATOM   1258 N N   . TYR A 1 171 ? 158.330 159.274 118.076 1.00 38.22 ? 199 TYR A N   1 
ATOM   1259 C CA  . TYR A 1 171 ? 158.725 159.107 119.468 1.00 38.22 ? 199 TYR A CA  1 
ATOM   1260 C C   . TYR A 1 171 ? 159.502 160.310 119.976 1.00 38.22 ? 199 TYR A C   1 
ATOM   1261 O O   . TYR A 1 171 ? 159.331 160.711 121.132 1.00 38.22 ? 199 TYR A O   1 
ATOM   1262 C CB  . TYR A 1 171 ? 159.563 157.842 119.643 1.00 38.22 ? 199 TYR A CB  1 
ATOM   1263 C CG  . TYR A 1 171 ? 160.023 157.630 121.064 1.00 38.22 ? 199 TYR A CG  1 
ATOM   1264 C CD1 . TYR A 1 171 ? 159.181 157.063 122.004 1.00 38.22 ? 199 TYR A CD1 1 
ATOM   1265 C CD2 . TYR A 1 171 ? 161.295 158.009 121.467 1.00 38.22 ? 199 TYR A CD2 1 
ATOM   1266 C CE1 . TYR A 1 171 ? 159.592 156.870 123.302 1.00 38.22 ? 199 TYR A CE1 1 
ATOM   1267 C CE2 . TYR A 1 171 ? 161.715 157.821 122.763 1.00 38.22 ? 199 TYR A CE2 1 
ATOM   1268 C CZ  . TYR A 1 171 ? 160.859 157.250 123.677 1.00 38.22 ? 199 TYR A CZ  1 
ATOM   1269 O OH  . TYR A 1 171 ? 161.266 157.059 124.976 1.00 38.22 ? 199 TYR A OH  1 
ATOM   1270 N N   . ALA A 1 172 ? 160.366 160.889 119.142 1.00 33.72 ? 200 ALA A N   1 
ATOM   1271 C CA  . ALA A 1 172 ? 161.164 162.025 119.585 1.00 33.72 ? 200 ALA A CA  1 
ATOM   1272 C C   . ALA A 1 172 ? 160.275 163.187 120.009 1.00 33.72 ? 200 ALA A C   1 
ATOM   1273 O O   . ALA A 1 172 ? 160.439 163.746 121.102 1.00 33.72 ? 200 ALA A O   1 
ATOM   1274 C CB  . ALA A 1 172 ? 162.124 162.454 118.475 1.00 33.72 ? 200 ALA A CB  1 
ATOM   1275 N N   . ILE A 1 173 ? 159.307 163.548 119.164 1.00 30.80 ? 201 ILE A N   1 
ATOM   1276 C CA  . ILE A 1 173 ? 158.458 164.699 119.452 1.00 30.80 ? 201 ILE A CA  1 
ATOM   1277 C C   . ILE A 1 173 ? 157.663 164.465 120.727 1.00 30.80 ? 201 ILE A C   1 
ATOM   1278 O O   . ILE A 1 173 ? 157.646 165.307 121.633 1.00 30.80 ? 201 ILE A O   1 
ATOM   1279 C CB  . ILE A 1 173 ? 157.527 164.991 118.263 1.00 30.80 ? 201 ILE A CB  1 
ATOM   1280 C CG1 . ILE A 1 173 ? 158.341 165.270 116.999 1.00 30.80 ? 201 ILE A CG1 1 
ATOM   1281 C CG2 . ILE A 1 173 ? 156.618 166.163 118.581 1.00 30.80 ? 201 ILE A CG2 1 
ATOM   1282 C CD1 . ILE A 1 173 ? 159.249 166.466 117.110 1.00 30.80 ? 201 ILE A CD1 1 
ATOM   1283 N N   . ALA A 1 174 ? 156.994 163.314 120.815 1.00 26.78 ? 202 ALA A N   1 
ATOM   1284 C CA  . ALA A 1 174 ? 156.145 163.040 121.968 1.00 26.78 ? 202 ALA A CA  1 
ATOM   1285 C C   . ALA A 1 174 ? 156.964 162.983 123.248 1.00 26.78 ? 202 ALA A C   1 
ATOM   1286 O O   . ALA A 1 174 ? 156.567 163.542 124.276 1.00 26.78 ? 202 ALA A O   1 
ATOM   1287 C CB  . ALA A 1 174 ? 155.377 161.736 121.760 1.00 26.78 ? 202 ALA A CB  1 
ATOM   1288 N N   . SER A 1 175 ? 158.193 162.477 123.161 1.00 22.70 ? 203 SER A N   1 
ATOM   1289 C CA  . SER A 1 175 ? 158.885 162.465 124.465 1.00 22.70 ? 203 SER A CA  1 
ATOM   1290 C C   . SER A 1 175 ? 159.492 163.805 124.792 1.00 22.70 ? 203 SER A C   1 
ATOM   1291 O O   . SER A 1 175 ? 159.336 164.214 125.940 1.00 22.70 ? 203 SER A O   1 
ATOM   1292 C CB  . SER A 1 175 ? 159.766 161.375 124.796 1.00 22.70 ? 203 SER A CB  1 
ATOM   1293 O OG  . SER A 1 175 ? 159.872 161.277 126.204 1.00 22.70 ? 203 SER A OG  1 
ATOM   1294 N N   . SER A 1 176 ? 160.003 164.559 123.842 1.00 19.02 ? 204 SER A N   1 
ATOM   1295 C CA  . SER A 1 176 ? 160.563 165.843 124.308 1.00 19.02 ? 204 SER A CA  1 
ATOM   1296 C C   . SER A 1 176 ? 159.456 166.685 124.920 1.00 19.02 ? 204 SER A C   1 
ATOM   1297 O O   . SER A 1 176 ? 159.672 167.174 126.021 1.00 19.02 ? 204 SER A O   1 
ATOM   1298 C CB  . SER A 1 176 ? 161.209 166.511 123.229 1.00 19.02 ? 204 SER A CB  1 
ATOM   1299 O OG  . SER A 1 176 ? 162.343 165.769 122.829 1.00 19.02 ? 204 SER A OG  1 
ATOM   1300 N N   . ILE A 1 177 ? 158.257 166.688 124.338 1.00 19.69 ? 205 ILE A N   1 
ATOM   1301 C CA  . ILE A 1 177 ? 157.078 167.517 124.778 1.00 19.69 ? 205 ILE A CA  1 
ATOM   1302 C C   . ILE A 1 177 ? 156.154 166.811 125.783 1.00 19.69 ? 205 ILE A C   1 
ATOM   1303 O O   . ILE A 1 177 ? 154.964 167.050 125.727 1.00 19.69 ? 205 ILE A O   1 
ATOM   1304 C CB  . ILE A 1 177 ? 156.306 168.092 123.575 1.00 19.69 ? 205 ILE A CB  1 
ATOM   1305 C CG1 . ILE A 1 177 ? 157.231 168.338 122.384 1.00 19.69 ? 205 ILE A CG1 1 
ATOM   1306 C CG2 . ILE A 1 177 ? 155.594 169.376 123.951 1.00 19.69 ? 205 ILE A CG2 1 
ATOM   1307 C CD1 . ILE A 1 177 ? 157.056 169.696 121.752 1.00 19.69 ? 205 ILE A CD1 1 
ATOM   1308 N N   . VAL A 1 178 ? 156.628 165.807 126.487 1.00 14.93 ? 206 VAL A N   1 
ATOM   1309 C CA  . VAL A 1 178 ? 155.894 165.232 127.626 1.00 14.93 ? 206 VAL A CA  1 
ATOM   1310 C C   . VAL A 1 178 ? 156.994 165.112 128.670 1.00 14.93 ? 206 VAL A C   1 
ATOM   1311 O O   . VAL A 1 178 ? 156.698 164.676 129.778 1.00 14.93 ? 206 VAL A O   1 
ATOM   1312 C CB  . VAL A 1 178 ? 155.248 163.892 127.292 1.00 14.93 ? 206 VAL A CB  1 
ATOM   1313 C CG1 . VAL A 1 178 ? 154.650 163.176 128.490 1.00 14.93 ? 206 VAL A CG1 1 
ATOM   1314 C CG2 . VAL A 1 178 ? 154.186 164.046 126.225 1.00 14.93 ? 206 VAL A CG2 1 
ATOM   1315 N N   . SER A 1 179 ? 158.232 165.550 128.372 1.00 16.62 ? 207 SER A N   1 
ATOM   1316 C CA  . SER A 1 179 ? 159.230 165.417 129.469 1.00 16.62 ? 207 SER A CA  1 
ATOM   1317 C C   . SER A 1 179 ? 160.127 166.617 129.706 1.00 16.62 ? 207 SER A C   1 
ATOM   1318 O O   . SER A 1 179 ? 160.543 166.872 130.832 1.00 16.62 ? 207 SER A O   1 
ATOM   1319 C CB  . SER A 1 179 ? 160.041 164.251 129.194 1.00 16.62 ? 207 SER A CB  1 
ATOM   1320 O OG  . SER A 1 179 ? 159.379 163.061 129.595 1.00 16.62 ? 207 SER A OG  1 
ATOM   1321 N N   . PHE A 1 180 ? 160.408 167.342 128.679 1.00 13.02 ? 208 PHE A N   1 
ATOM   1322 C CA  . PHE A 1 180 ? 161.261 168.481 128.992 1.00 13.02 ? 208 PHE A CA  1 
ATOM   1323 C C   . PHE A 1 180 ? 160.747 169.766 128.350 1.00 13.02 ? 208 PHE A C   1 
ATOM   1324 O O   . PHE A 1 180 ? 161.525 170.685 128.082 1.00 13.02 ? 208 PHE A O   1 
ATOM   1325 C CB  . PHE A 1 180 ? 162.709 168.191 128.573 1.00 13.02 ? 208 PHE A CB  1 
ATOM   1326 C CG  . PHE A 1 180 ? 163.717 169.182 129.093 1.00 13.02 ? 208 PHE A CG  1 
ATOM   1327 C CD1 . PHE A 1 180 ? 164.109 169.154 130.417 1.00 13.02 ? 208 PHE A CD1 1 
ATOM   1328 C CD2 . PHE A 1 180 ? 164.309 170.103 128.246 1.00 13.02 ? 208 PHE A CD2 1 
ATOM   1329 C CE1 . PHE A 1 180 ? 165.037 170.049 130.893 1.00 13.02 ? 208 PHE A CE1 1 
ATOM   1330 C CE2 . PHE A 1 180 ? 165.234 171.000 128.718 1.00 13.02 ? 208 PHE A CE2 1 
ATOM   1331 C CZ  . PHE A 1 180 ? 165.601 170.971 130.042 1.00 13.02 ? 208 PHE A CZ  1 
ATOM   1332 N N   . TYR A 1 181 ? 159.445 169.867 128.105 1.00 15.22 ? 209 TYR A N   1 
ATOM   1333 C CA  . TYR A 1 181 ? 158.931 171.129 127.593 1.00 15.22 ? 209 TYR A CA  1 
ATOM   1334 C C   . TYR A 1 181 ? 157.718 171.613 128.377 1.00 15.22 ? 209 TYR A C   1 
ATOM   1335 O O   . TYR A 1 181 ? 157.497 172.820 128.493 1.00 15.22 ? 209 TYR A O   1 
ATOM   1336 C CB  . TYR A 1 181 ? 158.616 171.003 126.105 1.00 15.22 ? 209 TYR A CB  1 
ATOM   1337 C CG  . TYR A 1 181 ? 159.839 171.215 125.242 1.00 15.22 ? 209 TYR A CG  1 
ATOM   1338 C CD1 . TYR A 1 181 ? 160.784 172.172 125.575 1.00 15.22 ? 209 TYR A CD1 1 
ATOM   1339 C CD2 . TYR A 1 181 ? 160.051 170.457 124.102 1.00 15.22 ? 209 TYR A CD2 1 
ATOM   1340 C CE1 . TYR A 1 181 ? 161.903 172.369 124.799 1.00 15.22 ? 209 TYR A CE1 1 
ATOM   1341 C CE2 . TYR A 1 181 ? 161.168 170.649 123.317 1.00 15.22 ? 209 TYR A CE2 1 
ATOM   1342 C CZ  . TYR A 1 181 ? 162.089 171.606 123.672 1.00 15.22 ? 209 TYR A CZ  1 
ATOM   1343 O OH  . TYR A 1 181 ? 163.202 171.796 122.892 1.00 15.22 ? 209 TYR A OH  1 
ATOM   1344 N N   . VAL A 1 182 ? 156.927 170.697 128.920 1.00 15.09 ? 210 VAL A N   1 
ATOM   1345 C CA  . VAL A 1 182 ? 155.838 171.092 129.809 1.00 15.09 ? 210 VAL A CA  1 
ATOM   1346 C C   . VAL A 1 182 ? 156.409 171.408 131.192 1.00 15.09 ? 210 VAL A C   1 
ATOM   1347 O O   . VAL A 1 182 ? 156.200 172.527 131.701 1.00 15.09 ? 210 VAL A O   1 
ATOM   1348 C CB  . VAL A 1 182 ? 154.742 170.013 129.860 1.00 15.09 ? 210 VAL A CB  1 
ATOM   1349 C CG1 . VAL A 1 182 ? 153.700 170.359 130.903 1.00 15.09 ? 210 VAL A CG1 1 
ATOM   1350 C CG2 . VAL A 1 182 ? 154.102 169.848 128.496 1.00 15.09 ? 210 VAL A CG2 1 
ATOM   1351 N N   . PRO A 1 183 ? 157.142 170.487 131.837 1.00 13.19 ? 211 PRO A N   1 
ATOM   1352 C CA  . PRO A 1 183 ? 157.712 170.829 133.146 1.00 13.19 ? 211 PRO A CA  1 
ATOM   1353 C C   . PRO A 1 183 ? 158.650 172.011 133.100 1.00 13.19 ? 211 PRO A C   1 
ATOM   1354 O O   . PRO A 1 183 ? 158.717 172.755 134.081 1.00 13.19 ? 211 PRO A O   1 
ATOM   1355 C CB  . PRO A 1 183 ? 158.440 169.544 133.558 1.00 13.19 ? 211 PRO A CB  1 
ATOM   1356 C CG  . PRO A 1 183 ? 157.753 168.478 132.817 1.00 13.19 ? 211 PRO A CG  1 
ATOM   1357 C CD  . PRO A 1 183 ? 157.448 169.087 131.492 1.00 13.19 ? 211 PRO A CD  1 
ATOM   1358 N N   . LEU A 1 184 ? 159.361 172.227 131.992 1.00 13.24 ? 212 LEU A N   1 
ATOM   1359 C CA  . LEU A 1 184 ? 160.265 173.370 131.914 1.00 13.24 ? 212 LEU A CA  1 
ATOM   1360 C C   . LEU A 1 184 ? 159.511 174.685 132.059 1.00 13.24 ? 212 LEU A C   1 
ATOM   1361 O O   . LEU A 1 184 ? 159.851 175.518 132.907 1.00 13.24 ? 212 LEU A O   1 
ATOM   1362 C CB  . LEU A 1 184 ? 161.033 173.352 130.599 1.00 13.24 ? 212 LEU A CB  1 
ATOM   1363 C CG  . LEU A 1 184 ? 162.038 174.496 130.513 1.00 13.24 ? 212 LEU A CG  1 
ATOM   1364 C CD1 . LEU A 1 184 ? 163.246 174.195 131.376 1.00 13.24 ? 212 LEU A CD1 1 
ATOM   1365 C CD2 . LEU A 1 184 ? 162.445 174.767 129.079 1.00 13.24 ? 212 LEU A CD2 1 
ATOM   1366 N N   . VAL A 1 185 ? 158.469 174.888 131.250 1.00 15.82 ? 213 VAL A N   1 
ATOM   1367 C CA  . VAL A 1 185 ? 157.737 176.149 131.326 1.00 15.82 ? 213 VAL A CA  1 
ATOM   1368 C C   . VAL A 1 185 ? 157.027 176.275 132.667 1.00 15.82 ? 213 VAL A C   1 
ATOM   1369 O O   . VAL A 1 185 ? 156.942 177.374 133.234 1.00 15.82 ? 213 VAL A O   1 
ATOM   1370 C CB  . VAL A 1 185 ? 156.764 176.295 130.141 1.00 15.82 ? 213 VAL A CB  1 
ATOM   1371 C CG1 . VAL A 1 185 ? 157.526 176.276 128.826 1.00 15.82 ? 213 VAL A CG1 1 
ATOM   1372 C CG2 . VAL A 1 185 ? 155.701 175.213 130.164 1.00 15.82 ? 213 VAL A CG2 1 
ATOM   1373 N N   . ILE A 1 186 ? 156.526 175.160 133.212 1.00 13.89 ? 214 ILE A N   1 
ATOM   1374 C CA  . ILE A 1 186 ? 155.844 175.232 134.503 1.00 13.89 ? 214 ILE A CA  1 
ATOM   1375 C C   . ILE A 1 186 ? 156.805 175.701 135.592 1.00 13.89 ? 214 ILE A C   1 
ATOM   1376 O O   . ILE A 1 186 ? 156.517 176.654 136.333 1.00 13.89 ? 214 ILE A O   1 
ATOM   1377 C CB  . ILE A 1 186 ? 155.209 173.876 134.854 1.00 13.89 ? 214 ILE A CB  1 
ATOM   1378 C CG1 . ILE A 1 186 ? 154.024 173.596 133.931 1.00 13.89 ? 214 ILE A CG1 1 
ATOM   1379 C CG2 . ILE A 1 186 ? 154.763 173.861 136.300 1.00 13.89 ? 214 ILE A CG2 1 
ATOM   1380 C CD1 . ILE A 1 186 ? 153.363 172.266 134.176 1.00 13.89 ? 214 ILE A CD1 1 
ATOM   1381 N N   . MET A 1 187 ? 157.968 175.052 135.698 1.00 12.80 ? 215 MET A N   1 
ATOM   1382 C CA  . MET A 1 187 ? 158.946 175.434 136.707 1.00 12.80 ? 215 MET A CA  1 
ATOM   1383 C C   . MET A 1 187 ? 159.578 176.781 136.419 1.00 12.80 ? 215 MET A C   1 
ATOM   1384 O O   . MET A 1 187 ? 160.227 177.336 137.308 1.00 12.80 ? 215 MET A O   1 
ATOM   1385 C CB  . MET A 1 187 ? 160.048 174.379 136.834 1.00 12.80 ? 215 MET A CB  1 
ATOM   1386 C CG  . MET A 1 187 ? 160.854 174.165 135.566 1.00 12.80 ? 215 MET A CG  1 
ATOM   1387 S SD  . MET A 1 187 ? 162.398 173.258 135.754 1.00 12.80 ? 215 MET A SD  1 
ATOM   1388 C CE  . MET A 1 187 ? 163.289 174.354 136.832 1.00 12.80 ? 215 MET A CE  1 
ATOM   1389 N N   . VAL A 1 188 ? 159.431 177.311 135.207 1.00 16.61 ? 216 VAL A N   1 
ATOM   1390 C CA  . VAL A 1 188 ? 159.900 178.670 134.972 1.00 16.61 ? 216 VAL A CA  1 
ATOM   1391 C C   . VAL A 1 188 ? 158.900 179.694 135.495 1.00 16.61 ? 216 VAL A C   1 
ATOM   1392 O O   . VAL A 1 188 ? 159.266 180.577 136.281 1.00 16.61 ? 216 VAL A O   1 
ATOM   1393 C CB  . VAL A 1 188 ? 160.225 178.898 133.487 1.00 16.61 ? 216 VAL A CB  1 
ATOM   1394 C CG1 . VAL A 1 188 ? 160.480 180.366 133.242 1.00 16.61 ? 216 VAL A CG1 1 
ATOM   1395 C CG2 . VAL A 1 188 ? 161.465 178.124 133.110 1.00 16.61 ? 216 VAL A CG2 1 
ATOM   1396 N N   . PHE A 1 189 ? 157.623 179.617 135.088 1.00 20.79 ? 217 PHE A N   1 
ATOM   1397 C CA  . PHE A 1 189 ? 156.781 180.743 135.496 1.00 20.79 ? 217 PHE A CA  1 
ATOM   1398 C C   . PHE A 1 189 ? 156.370 180.638 136.961 1.00 20.79 ? 217 PHE A C   1 
ATOM   1399 O O   . PHE A 1 189 ? 156.181 181.673 137.612 1.00 20.79 ? 217 PHE A O   1 
ATOM   1400 C CB  . PHE A 1 189 ? 155.513 180.932 134.650 1.00 20.79 ? 217 PHE A CB  1 
ATOM   1401 C CG  . PHE A 1 189 ? 154.509 179.823 134.738 1.00 20.79 ? 217 PHE A CG  1 
ATOM   1402 C CD1 . PHE A 1 189 ? 154.541 178.747 133.884 1.00 20.79 ? 217 PHE A CD1 1 
ATOM   1403 C CD2 . PHE A 1 189 ? 153.479 179.905 135.662 1.00 20.79 ? 217 PHE A CD2 1 
ATOM   1404 C CE1 . PHE A 1 189 ? 153.586 177.751 133.967 1.00 20.79 ? 217 PHE A CE1 1 
ATOM   1405 C CE2 . PHE A 1 189 ? 152.526 178.916 135.752 1.00 20.79 ? 217 PHE A CE2 1 
ATOM   1406 C CZ  . PHE A 1 189 ? 152.579 177.836 134.905 1.00 20.79 ? 217 PHE A CZ  1 
ATOM   1407 N N   . VAL A 1 190 ? 156.229 179.424 137.507 1.00 18.75 ? 218 VAL A N   1 
ATOM   1408 C CA  . VAL A 1 190 ? 155.917 179.316 138.930 1.00 18.75 ? 218 VAL A CA  1 
ATOM   1409 C C   . VAL A 1 190 ? 157.017 179.963 139.759 1.00 18.75 ? 218 VAL A C   1 
ATOM   1410 O O   . VAL A 1 190 ? 156.751 180.733 140.691 1.00 18.75 ? 218 VAL A O   1 
ATOM   1411 C CB  . VAL A 1 190 ? 155.704 177.844 139.325 1.00 18.75 ? 218 VAL A CB  1 
ATOM   1412 C CG1 . VAL A 1 190 ? 155.791 177.686 140.823 1.00 18.75 ? 218 VAL A CG1 1 
ATOM   1413 C CG2 . VAL A 1 190 ? 154.365 177.355 138.828 1.00 18.75 ? 218 VAL A CG2 1 
ATOM   1414 N N   . TYR A 1 191 ? 158.268 179.693 139.417 1.00 19.87 ? 219 TYR A N   1 
ATOM   1415 C CA  . TYR A 1 191 ? 159.348 180.248 140.210 1.00 19.87 ? 219 TYR A CA  1 
ATOM   1416 C C   . TYR A 1 191 ? 159.563 181.728 139.914 1.00 19.87 ? 219 TYR A C   1 
ATOM   1417 O O   . TYR A 1 191 ? 160.052 182.463 140.784 1.00 19.87 ? 219 TYR A O   1 
ATOM   1418 C CB  . TYR A 1 191 ? 160.618 179.443 139.968 1.00 19.87 ? 219 TYR A CB  1 
ATOM   1419 C CG  . TYR A 1 191 ? 161.695 179.717 140.970 1.00 19.87 ? 219 TYR A CG  1 
ATOM   1420 C CD1 . TYR A 1 191 ? 161.632 179.158 142.237 1.00 19.87 ? 219 TYR A CD1 1 
ATOM   1421 C CD2 . TYR A 1 191 ? 162.775 180.514 140.659 1.00 19.87 ? 219 TYR A CD2 1 
ATOM   1422 C CE1 . TYR A 1 191 ? 162.608 179.390 143.166 1.00 19.87 ? 219 TYR A CE1 1 
ATOM   1423 C CE2 . TYR A 1 191 ? 163.760 180.748 141.582 1.00 19.87 ? 219 TYR A CE2 1 
ATOM   1424 C CZ  . TYR A 1 191 ? 163.672 180.189 142.835 1.00 19.87 ? 219 TYR A CZ  1 
ATOM   1425 O OH  . TYR A 1 191 ? 164.656 180.429 143.760 1.00 19.87 ? 219 TYR A OH  1 
ATOM   1426 N N   . SER A 1 192 ? 159.170 182.195 138.725 1.00 23.45 ? 220 SER A N   1 
ATOM   1427 C CA  . SER A 1 192 ? 159.134 183.634 138.486 1.00 23.45 ? 220 SER A CA  1 
ATOM   1428 C C   . SER A 1 192 ? 158.133 184.316 139.410 1.00 23.45 ? 220 SER A C   1 
ATOM   1429 O O   . SER A 1 192 ? 158.417 185.382 139.972 1.00 23.45 ? 220 SER A O   1 
ATOM   1430 C CB  . SER A 1 192 ? 158.793 183.920 137.026 1.00 23.45 ? 220 SER A CB  1 
ATOM   1431 O OG  . SER A 1 192 ? 159.846 183.515 136.171 1.00 23.45 ? 220 SER A OG  1 
ATOM   1432 N N   . ARG A 1 193 ? 156.952 183.716 139.581 1.00 26.94 ? 221 ARG A N   1 
ATOM   1433 C CA  . ARG A 1 193 ? 156.000 184.248 140.552 1.00 26.94 ? 221 ARG A CA  1 
ATOM   1434 C C   . ARG A 1 193 ? 156.557 184.183 141.967 1.00 26.94 ? 221 ARG A C   1 
ATOM   1435 O O   . ARG A 1 193 ? 156.247 185.045 142.795 1.00 26.94 ? 221 ARG A O   1 
ATOM   1436 C CB  . ARG A 1 193 ? 154.674 183.496 140.476 1.00 26.94 ? 221 ARG A CB  1 
ATOM   1437 C CG  . ARG A 1 193 ? 153.947 183.654 139.160 1.00 26.94 ? 221 ARG A CG  1 
ATOM   1438 C CD  . ARG A 1 193 ? 153.646 185.111 138.868 1.00 26.94 ? 221 ARG A CD  1 
ATOM   1439 N NE  . ARG A 1 193 ? 153.352 185.330 137.455 1.00 26.94 ? 221 ARG A NE  1 
ATOM   1440 C CZ  . ARG A 1 193 ? 153.961 186.233 136.693 1.00 26.94 ? 221 ARG A CZ  1 
ATOM   1441 N NH1 . ARG A 1 193 ? 153.626 186.362 135.417 1.00 26.94 ? 221 ARG A NH1 1 
ATOM   1442 N NH2 . ARG A 1 193 ? 154.906 187.005 137.206 1.00 26.94 ? 221 ARG A NH2 1 
ATOM   1443 N N   . VAL A 1 194 ? 157.371 183.169 142.265 1.00 24.51 ? 222 VAL A N   1 
ATOM   1444 C CA  . VAL A 1 194 ? 158.003 183.094 143.582 1.00 24.51 ? 222 VAL A CA  1 
ATOM   1445 C C   . VAL A 1 194 ? 158.911 184.296 143.811 1.00 24.51 ? 222 VAL A C   1 
ATOM   1446 O O   . VAL A 1 194 ? 158.862 184.936 144.868 1.00 24.51 ? 222 VAL A O   1 
ATOM   1447 C CB  . VAL A 1 194 ? 158.776 181.776 143.740 1.00 24.51 ? 222 VAL A CB  1 
ATOM   1448 C CG1 . VAL A 1 194 ? 159.657 181.841 144.967 1.00 24.51 ? 222 VAL A CG1 1 
ATOM   1449 C CG2 . VAL A 1 194 ? 157.816 180.626 143.849 1.00 24.51 ? 222 VAL A CG2 1 
ATOM   1450 N N   . PHE A 1 195 ? 159.763 184.617 142.833 1.00 29.78 ? 223 PHE A N   1 
ATOM   1451 C CA  . PHE A 1 195 ? 160.575 185.830 142.963 1.00 29.78 ? 223 PHE A CA  1 
ATOM   1452 C C   . PHE A 1 195 ? 159.725 187.092 143.054 1.00 29.78 ? 223 PHE A C   1 
ATOM   1453 O O   . PHE A 1 195 ? 160.047 188.001 143.829 1.00 29.78 ? 223 PHE A O   1 
ATOM   1454 C CB  . PHE A 1 195 ? 161.598 185.960 141.836 1.00 29.78 ? 223 PHE A CB  1 
ATOM   1455 C CG  . PHE A 1 195 ? 162.800 185.083 142.002 1.00 29.78 ? 223 PHE A CG  1 
ATOM   1456 C CD1 . PHE A 1 195 ? 163.078 184.497 143.224 1.00 29.78 ? 223 PHE A CD1 1 
ATOM   1457 C CD2 . PHE A 1 195 ? 163.699 184.911 140.967 1.00 29.78 ? 223 PHE A CD2 1 
ATOM   1458 C CE1 . PHE A 1 195 ? 164.207 183.716 143.395 1.00 29.78 ? 223 PHE A CE1 1 
ATOM   1459 C CE2 . PHE A 1 195 ? 164.830 184.131 141.135 1.00 29.78 ? 223 PHE A CE2 1 
ATOM   1460 C CZ  . PHE A 1 195 ? 165.085 183.540 142.352 1.00 29.78 ? 223 PHE A CZ  1 
ATOM   1461 N N   . GLN A 1 196 ? 158.654 187.186 142.266 1.00 35.14 ? 224 GLN A N   1 
ATOM   1462 C CA  . GLN A 1 196 ? 157.799 188.369 142.354 1.00 35.14 ? 224 GLN A CA  1 
ATOM   1463 C C   . GLN A 1 196 ? 157.255 188.544 143.768 1.00 35.14 ? 224 GLN A C   1 
ATOM   1464 O O   . GLN A 1 196 ? 157.331 189.635 144.350 1.00 35.14 ? 224 GLN A O   1 
ATOM   1465 C CB  . GLN A 1 196 ? 156.649 188.273 141.353 1.00 35.14 ? 224 GLN A CB  1 
ATOM   1466 C CG  . GLN A 1 196 ? 156.901 188.990 140.043 1.00 35.14 ? 224 GLN A CG  1 
ATOM   1467 C CD  . GLN A 1 196 ? 155.630 189.196 139.246 1.00 35.14 ? 224 GLN A CD  1 
ATOM   1468 O OE1 . GLN A 1 196 ? 154.544 188.811 139.678 1.00 35.14 ? 224 GLN A OE1 1 
ATOM   1469 N NE2 . GLN A 1 196 ? 155.759 189.804 138.074 1.00 35.14 ? 224 GLN A NE2 1 
ATOM   1470 N N   . GLU A 1 197 ? 156.722 187.465 144.343 1.00 38.10 ? 225 GLU A N   1 
ATOM   1471 C CA  . GLU A 1 197 ? 156.139 187.548 145.676 1.00 38.10 ? 225 GLU A CA  1 
ATOM   1472 C C   . GLU A 1 197 ? 157.198 187.829 146.731 1.00 38.10 ? 225 GLU A C   1 
ATOM   1473 O O   . GLU A 1 197 ? 156.942 188.576 147.679 1.00 38.10 ? 225 GLU A O   1 
ATOM   1474 C CB  . GLU A 1 197 ? 155.379 186.267 146.003 1.00 38.10 ? 225 GLU A CB  1 
ATOM   1475 C CG  . GLU A 1 197 ? 154.103 186.106 145.202 1.00 38.10 ? 225 GLU A CG  1 
ATOM   1476 C CD  . GLU A 1 197 ? 153.166 187.288 145.353 1.00 38.10 ? 225 GLU A CD  1 
ATOM   1477 O OE1 . GLU A 1 197 ? 153.103 187.867 146.458 1.00 38.10 ? 225 GLU A OE1 1 
ATOM   1478 O OE2 . GLU A 1 197 ? 152.495 187.642 144.362 1.00 38.10 ? 225 GLU A OE2 1 
ATOM   1479 N N   . ALA A 1 198 ? 158.388 187.242 146.595 1.00 38.46 ? 226 ALA A N   1 
ATOM   1480 C CA  . ALA A 1 198 ? 159.445 187.518 147.562 1.00 38.46 ? 226 ALA A CA  1 
ATOM   1481 C C   . ALA A 1 198 ? 159.864 188.981 147.520 1.00 38.46 ? 226 ALA A C   1 
ATOM   1482 O O   . ALA A 1 198 ? 160.011 189.622 148.569 1.00 38.46 ? 226 ALA A O   1 
ATOM   1483 C CB  . ALA A 1 198 ? 160.647 186.614 147.305 1.00 38.46 ? 226 ALA A CB  1 
ATOM   1484 N N   . LYS A 1 199 ? 160.048 189.530 146.318 1.00 41.10 ? 227 LYS A N   1 
ATOM   1485 C CA  . LYS A 1 199 ? 160.454 190.926 146.202 1.00 41.10 ? 227 LYS A CA  1 
ATOM   1486 C C   . LYS A 1 199 ? 159.379 191.862 146.741 1.00 41.10 ? 227 LYS A C   1 
ATOM   1487 O O   . LYS A 1 199 ? 159.694 192.872 147.380 1.00 41.10 ? 227 LYS A O   1 
ATOM   1488 C CB  . LYS A 1 199 ? 160.782 191.260 144.748 1.00 41.10 ? 227 LYS A CB  1 
ATOM   1489 N N   . ARG A 1 200 ? 158.104 191.551 146.490 1.00 45.37 ? 228 ARG A N   1 
ATOM   1490 C CA  . ARG A 1 200 ? 157.043 192.407 147.011 1.00 45.37 ? 228 ARG A CA  1 
ATOM   1491 C C   . ARG A 1 200 ? 156.926 192.293 148.528 1.00 45.37 ? 228 ARG A C   1 
ATOM   1492 O O   . ARG A 1 200 ? 156.730 193.301 149.216 1.00 45.37 ? 228 ARG A O   1 
ATOM   1493 C CB  . ARG A 1 200 ? 155.714 192.066 146.341 1.00 45.37 ? 228 ARG A CB  1 
ATOM   1494 C CG  . ARG A 1 200 ? 154.588 193.020 146.694 1.00 45.37 ? 228 ARG A CG  1 
ATOM   1495 C CD  . ARG A 1 200 ? 153.272 192.280 146.880 1.00 45.37 ? 228 ARG A CD  1 
ATOM   1496 N NE  . ARG A 1 200 ? 153.437 191.033 147.623 1.00 45.37 ? 228 ARG A NE  1 
ATOM   1497 C CZ  . ARG A 1 200 ? 153.685 190.959 148.927 1.00 45.37 ? 228 ARG A CZ  1 
ATOM   1498 N NH1 . ARG A 1 200 ? 153.796 192.062 149.652 1.00 45.37 ? 228 ARG A NH1 1 
ATOM   1499 N NH2 . ARG A 1 200 ? 153.819 189.775 149.508 1.00 45.37 ? 228 ARG A NH2 1 
ATOM   1500 N N   . GLN A 1 201 ? 157.046 191.077 149.068 1.00 42.56 ? 229 GLN A N   1 
ATOM   1501 C CA  . GLN A 1 201 ? 156.919 190.871 150.507 1.00 42.56 ? 229 GLN A CA  1 
ATOM   1502 C C   . GLN A 1 201 ? 158.070 191.502 151.275 1.00 42.56 ? 229 GLN A C   1 
ATOM   1503 O O   . GLN A 1 201 ? 157.884 191.945 152.414 1.00 42.56 ? 229 GLN A O   1 
ATOM   1504 C CB  . GLN A 1 201 ? 156.844 189.374 150.811 1.00 42.56 ? 229 GLN A CB  1 
ATOM   1505 C CG  . GLN A 1 201 ? 156.585 189.030 152.265 1.00 42.56 ? 229 GLN A CG  1 
ATOM   1506 C CD  . GLN A 1 201 ? 156.944 187.593 152.588 1.00 42.56 ? 229 GLN A CD  1 
ATOM   1507 O OE1 . GLN A 1 201 ? 157.828 187.009 151.964 1.00 42.56 ? 229 GLN A OE1 1 
ATOM   1508 N NE2 . GLN A 1 201 ? 156.260 187.015 153.567 1.00 42.56 ? 229 GLN A NE2 1 
ATOM   1509 N N   . LEU A 1 202 ? 159.262 191.551 150.680 1.00 46.16 ? 230 LEU A N   1 
ATOM   1510 C CA  . LEU A 1 202 ? 160.411 192.122 151.367 1.00 46.16 ? 230 LEU A CA  1 
ATOM   1511 C C   . LEU A 1 202 ? 160.271 193.620 151.620 1.00 46.16 ? 230 LEU A C   1 
ATOM   1512 O O   . LEU A 1 202 ? 161.030 194.169 152.425 1.00 46.16 ? 230 LEU A O   1 
ATOM   1513 C CB  . LEU A 1 202 ? 161.683 191.840 150.562 1.00 46.16 ? 230 LEU A CB  1 
ATOM   1514 C CG  . LEU A 1 202 ? 163.043 192.217 151.149 1.00 46.16 ? 230 LEU A CG  1 
ATOM   1515 C CD1 . LEU A 1 202 ? 164.040 191.097 150.928 1.00 46.16 ? 230 LEU A CD1 1 
ATOM   1516 C CD2 . LEU A 1 202 ? 163.552 193.510 150.537 1.00 46.16 ? 230 LEU A CD2 1 
ATOM   1517 N N   . ASP A 1 203 ? 159.315 194.288 150.979 1.00 46.66 ? 231 ASP A N   1 
ATOM   1518 C CA  . ASP A 1 203 ? 159.141 195.732 151.086 1.00 46.66 ? 231 ASP A CA  1 
ATOM   1519 C C   . ASP A 1 203 ? 157.709 196.096 151.466 1.00 46.66 ? 231 ASP A C   1 
ATOM   1520 O O   . ASP A 1 203 ? 157.094 196.975 150.863 1.00 46.66 ? 231 ASP A O   1 
ATOM   1521 C CB  . ASP A 1 203 ? 159.538 196.414 149.780 1.00 46.66 ? 231 ASP A CB  1 
ATOM   1522 C CG  . ASP A 1 203 ? 159.699 197.909 149.928 1.00 46.66 ? 231 ASP A CG  1 
ATOM   1523 O OD1 . ASP A 1 203 ? 159.560 198.414 151.060 1.00 46.66 ? 231 ASP A OD1 1 
ATOM   1524 O OD2 . ASP A 1 203 ? 159.956 198.583 148.909 1.00 46.66 ? 231 ASP A OD2 1 
ATOM   1525 N N   . ALA A 1 204 ? 157.155 195.427 152.473 1.00 39.77 ? 232 ALA A N   1 
ATOM   1526 C CA  . ALA A 1 204 ? 155.756 195.648 152.841 1.00 39.77 ? 232 ALA A CA  1 
ATOM   1527 C C   . ALA A 1 204 ? 155.598 196.712 153.925 1.00 39.77 ? 232 ALA A C   1 
ATOM   1528 O O   . ALA A 1 204 ? 154.926 196.494 154.933 1.00 39.77 ? 232 ALA A O   1 
ATOM   1529 C CB  . ALA A 1 204 ? 155.127 194.331 153.276 1.00 39.77 ? 232 ALA A CB  1 
ATOM   1530 N N   . ASP A 1 205 ? 156.249 197.863 153.736 1.00 40.60 ? 233 ASP A N   1 
ATOM   1531 C CA  . ASP A 1 205 ? 155.977 199.101 154.468 1.00 40.60 ? 233 ASP A CA  1 
ATOM   1532 C C   . ASP A 1 205 ? 156.465 198.944 155.911 1.00 40.60 ? 233 ASP A C   1 
ATOM   1533 O O   . ASP A 1 205 ? 156.678 199.931 156.620 1.00 40.60 ? 233 ASP A O   1 
ATOM   1534 C CB  . ASP A 1 205 ? 154.469 199.414 154.336 1.00 40.60 ? 233 ASP A CB  1 
ATOM   1535 C CG  . ASP A 1 205 ? 153.958 200.553 155.235 1.00 40.60 ? 233 ASP A CG  1 
ATOM   1536 O OD1 . ASP A 1 205 ? 154.653 201.095 156.108 1.00 40.60 ? 233 ASP A OD1 1 
ATOM   1537 O OD2 . ASP A 1 205 ? 152.780 200.921 155.044 1.00 40.60 ? 233 ASP A OD2 1 
ATOM   1538 N N   . GLU A 1 206 ? 156.781 197.716 156.314 1.00 35.57 ? 234 GLU A N   1 
ATOM   1539 C CA  . GLU A 1 206 ? 157.304 197.425 157.643 1.00 35.57 ? 234 GLU A CA  1 
ATOM   1540 C C   . GLU A 1 206 ? 158.822 197.340 157.648 1.00 35.57 ? 234 GLU A C   1 
ATOM   1541 O O   . GLU A 1 206 ? 159.477 197.902 158.530 1.00 35.57 ? 234 GLU A O   1 
ATOM   1542 C CB  . GLU A 1 206 ? 156.707 196.112 158.162 1.00 35.57 ? 234 GLU A CB  1 
ATOM   1543 C CG  . GLU A 1 206 ? 157.220 195.658 159.518 1.00 35.57 ? 234 GLU A CG  1 
ATOM   1544 C CD  . GLU A 1 206 ? 156.775 196.552 160.649 1.00 35.57 ? 234 GLU A CD  1 
ATOM   1545 O OE1 . GLU A 1 206 ? 155.767 197.268 160.483 1.00 35.57 ? 234 GLU A OE1 1 
ATOM   1546 O OE2 . GLU A 1 206 ? 157.420 196.520 161.717 1.00 35.57 ? 234 GLU A OE2 1 
ATOM   1547 N N   . ILE A 1 207 ? 159.391 196.644 156.664 1.00 30.42 ? 235 ILE A N   1 
ATOM   1548 C CA  . ILE A 1 207 ? 160.839 196.537 156.553 1.00 30.42 ? 235 ILE A CA  1 
ATOM   1549 C C   . ILE A 1 207 ? 161.460 197.893 156.252 1.00 30.42 ? 235 ILE A C   1 
ATOM   1550 O O   . ILE A 1 207 ? 162.617 198.144 156.603 1.00 30.42 ? 235 ILE A O   1 
ATOM   1551 C CB  . ILE A 1 207 ? 161.205 195.475 155.496 1.00 30.42 ? 235 ILE A CB  1 
ATOM   1552 C CG1 . ILE A 1 207 ? 160.770 194.087 155.964 1.00 30.42 ? 235 ILE A CG1 1 
ATOM   1553 C CG2 . ILE A 1 207 ? 162.686 195.458 155.222 1.00 30.42 ? 235 ILE A CG2 1 
ATOM   1554 C CD1 . ILE A 1 207 ? 159.379 193.692 155.548 1.00 30.42 ? 235 ILE A CD1 1 
ATOM   1555 N N   . LYS A 1 208 ? 160.708 198.799 155.624 1.00 28.00 ? 236 LYS A N   1 
ATOM   1556 C CA  . LYS A 1 208 ? 161.255 200.121 155.334 1.00 28.00 ? 236 LYS A CA  1 
ATOM   1557 C C   . LYS A 1 208 ? 161.510 200.917 156.610 1.00 28.00 ? 236 LYS A C   1 
ATOM   1558 O O   . LYS A 1 208 ? 162.506 201.643 156.706 1.00 28.00 ? 236 LYS A O   1 
ATOM   1559 C CB  . LYS A 1 208 ? 160.323 200.887 154.400 1.00 28.00 ? 236 LYS A CB  1 
ATOM   1560 C CG  . LYS A 1 208 ? 160.952 202.132 153.801 1.00 28.00 ? 236 LYS A CG  1 
ATOM   1561 C CD  . LYS A 1 208 ? 162.296 201.831 153.153 1.00 28.00 ? 236 LYS A CD  1 
ATOM   1562 C CE  . LYS A 1 208 ? 162.170 200.818 152.026 1.00 28.00 ? 236 LYS A CE  1 
ATOM   1563 N NZ  . LYS A 1 208 ? 163.499 200.440 151.478 1.00 28.00 ? 236 LYS A NZ  1 
ATOM   1564 N N   . ARG A 1 209 ? 160.620 200.803 157.597 1.00 27.70 ? 237 ARG A N   1 
ATOM   1565 C CA  . ARG A 1 209 ? 160.856 201.469 158.874 1.00 27.70 ? 237 ARG A CA  1 
ATOM   1566 C C   . ARG A 1 209 ? 162.102 200.919 159.558 1.00 27.70 ? 237 ARG A C   1 
ATOM   1567 O O   . ARG A 1 209 ? 162.910 201.680 160.111 1.00 27.70 ? 237 ARG A O   1 
ATOM   1568 C CB  . ARG A 1 209 ? 159.632 201.319 159.774 1.00 27.70 ? 237 ARG A CB  1 
ATOM   1569 C CG  . ARG A 1 209 ? 159.852 201.772 161.201 1.00 27.70 ? 237 ARG A CG  1 
ATOM   1570 C CD  . ARG A 1 209 ? 158.553 201.768 161.978 1.00 27.70 ? 237 ARG A CD  1 
ATOM   1571 N NE  . ARG A 1 209 ? 157.602 202.728 161.431 1.00 27.70 ? 237 ARG A NE  1 
ATOM   1572 C CZ  . ARG A 1 209 ? 156.449 202.396 160.862 1.00 27.70 ? 237 ARG A CZ  1 
ATOM   1573 N NH1 . ARG A 1 209 ? 155.646 203.338 160.389 1.00 27.70 ? 237 ARG A NH1 1 
ATOM   1574 N NH2 . ARG A 1 209 ? 156.101 201.121 160.764 1.00 27.70 ? 237 ARG A NH2 1 
ATOM   1575 N N   . LEU A 1 210 ? 162.277 199.595 159.526 1.00 21.96 ? 238 LEU A N   1 
ATOM   1576 C CA  . LEU A 1 210 ? 163.482 198.998 160.089 1.00 21.96 ? 238 LEU A CA  1 
ATOM   1577 C C   . LEU A 1 210 ? 164.722 199.466 159.345 1.00 21.96 ? 238 LEU A C   1 
ATOM   1578 O O   . LEU A 1 210 ? 165.771 199.680 159.955 1.00 21.96 ? 238 LEU A O   1 
ATOM   1579 C CB  . LEU A 1 210 ? 163.383 197.476 160.058 1.00 21.96 ? 238 LEU A CB  1 
ATOM   1580 C CG  . LEU A 1 210 ? 162.734 196.848 161.287 1.00 21.96 ? 238 LEU A CG  1 
ATOM   1581 C CD1 . LEU A 1 210 ? 163.008 195.356 161.338 1.00 21.96 ? 238 LEU A CD1 1 
ATOM   1582 C CD2 . LEU A 1 210 ? 163.222 197.536 162.540 1.00 21.96 ? 238 LEU A CD2 1 
ATOM   1583 N N   . GLY A 1 211 ? 164.624 199.629 158.026 1.00 20.10 ? 239 GLY A N   1 
ATOM   1584 C CA  . GLY A 1 211 ? 165.750 200.152 157.272 1.00 20.10 ? 239 GLY A CA  1 
ATOM   1585 C C   . GLY A 1 211 ? 166.091 201.578 157.653 1.00 20.10 ? 239 GLY A C   1 
ATOM   1586 O O   . GLY A 1 211 ? 167.265 201.946 157.738 1.00 20.10 ? 239 GLY A O   1 
ATOM   1587 N N   . LYS A 1 212 ? 165.069 202.401 157.884 1.00 20.53 ? 240 LYS A N   1 
ATOM   1588 C CA  . LYS A 1 212 ? 165.322 203.769 158.323 1.00 20.53 ? 240 LYS A CA  1 
ATOM   1589 C C   . LYS A 1 212 ? 165.999 203.793 159.688 1.00 20.53 ? 240 LYS A C   1 
ATOM   1590 O O   . LYS A 1 212 ? 166.947 204.557 159.906 1.00 20.53 ? 240 LYS A O   1 
ATOM   1591 C CB  . LYS A 1 212 ? 164.020 204.564 158.357 1.00 20.53 ? 240 LYS A CB  1 
ATOM   1592 C CG  . LYS A 1 212 ? 164.184 205.977 158.886 1.00 20.53 ? 240 LYS A CG  1 
ATOM   1593 C CD  . LYS A 1 212 ? 165.080 206.803 157.983 1.00 20.53 ? 240 LYS A CD  1 
ATOM   1594 C CE  . LYS A 1 212 ? 164.881 208.289 158.227 1.00 20.53 ? 240 LYS A CE  1 
ATOM   1595 N NZ  . LYS A 1 212 ? 163.934 208.897 157.254 1.00 20.53 ? 240 LYS A NZ  1 
ATOM   1596 N N   . ARG A 1 213 ? 165.536 202.955 160.618 1.00 17.50 ? 241 ARG A N   1 
ATOM   1597 C CA  . ARG A 1 213 ? 166.186 202.894 161.928 1.00 17.50 ? 241 ARG A CA  1 
ATOM   1598 C C   . ARG A 1 213 ? 167.615 202.369 161.816 1.00 17.50 ? 241 ARG A C   1 
ATOM   1599 O O   . ARG A 1 213 ? 168.521 202.860 162.500 1.00 17.50 ? 241 ARG A O   1 
ATOM   1600 C CB  . ARG A 1 213 ? 165.373 202.029 162.887 1.00 17.50 ? 241 ARG A CB  1 
ATOM   1601 C CG  . ARG A 1 213 ? 166.034 201.853 164.241 1.00 17.50 ? 241 ARG A CG  1 
ATOM   1602 C CD  . ARG A 1 213 ? 166.201 203.190 164.939 1.00 17.50 ? 241 ARG A CD  1 
ATOM   1603 N NE  . ARG A 1 213 ? 166.668 203.052 166.315 1.00 17.50 ? 241 ARG A NE  1 
ATOM   1604 C CZ  . ARG A 1 213 ? 167.174 204.049 167.033 1.00 17.50 ? 241 ARG A CZ  1 
ATOM   1605 N NH1 . ARG A 1 213 ? 167.279 205.259 166.507 1.00 17.50 ? 241 ARG A NH1 1 
ATOM   1606 N NH2 . ARG A 1 213 ? 167.571 203.839 168.277 1.00 17.50 ? 241 ARG A NH2 1 
ATOM   1607 N N   . PHE A 1 214 ? 167.829 201.365 160.968 1.00 15.37 ? 242 PHE A N   1 
ATOM   1608 C CA  . PHE A 1 214 ? 169.165 200.851 160.700 1.00 15.37 ? 242 PHE A CA  1 
ATOM   1609 C C   . PHE A 1 214 ? 170.091 201.963 160.235 1.00 15.37 ? 242 PHE A C   1 
ATOM   1610 O O   . PHE A 1 214 ? 171.182 202.148 160.780 1.00 15.37 ? 242 PHE A O   1 
ATOM   1611 C CB  . PHE A 1 214 ? 169.057 199.747 159.649 1.00 15.37 ? 242 PHE A CB  1 
ATOM   1612 C CG  . PHE A 1 214 ? 170.364 199.165 159.210 1.00 15.37 ? 242 PHE A CG  1 
ATOM   1613 C CD1 . PHE A 1 214 ? 170.763 197.929 159.668 1.00 15.37 ? 242 PHE A CD1 1 
ATOM   1614 C CD2 . PHE A 1 214 ? 171.158 199.814 158.289 1.00 15.37 ? 242 PHE A CD2 1 
ATOM   1615 C CE1 . PHE A 1 214 ? 171.944 197.373 159.252 1.00 15.37 ? 242 PHE A CE1 1 
ATOM   1616 C CE2 . PHE A 1 214 ? 172.342 199.265 157.874 1.00 15.37 ? 242 PHE A CE2 1 
ATOM   1617 C CZ  . PHE A 1 214 ? 172.735 198.042 158.354 1.00 15.37 ? 242 PHE A CZ  1 
ATOM   1618 N N   . LYS A 1 215 ? 169.663 202.722 159.226 1.00 20.01 ? 243 LYS A N   1 
ATOM   1619 C CA  . LYS A 1 215 ? 170.498 203.800 158.707 1.00 20.01 ? 243 LYS A CA  1 
ATOM   1620 C C   . LYS A 1 215 ? 170.661 204.928 159.718 1.00 20.01 ? 243 LYS A C   1 
ATOM   1621 O O   . LYS A 1 215 ? 171.625 205.695 159.637 1.00 20.01 ? 243 LYS A O   1 
ATOM   1622 C CB  . LYS A 1 215 ? 169.914 204.328 157.400 1.00 20.01 ? 243 LYS A CB  1 
ATOM   1623 C CG  . LYS A 1 215 ? 169.973 203.328 156.259 1.00 20.01 ? 243 LYS A CG  1 
ATOM   1624 C CD  . LYS A 1 215 ? 169.145 203.788 155.073 1.00 20.01 ? 243 LYS A CD  1 
ATOM   1625 C CE  . LYS A 1 215 ? 169.621 205.133 154.550 1.00 20.01 ? 243 LYS A CE  1 
ATOM   1626 N NZ  . LYS A 1 215 ? 168.495 205.954 154.024 1.00 20.01 ? 243 LYS A NZ  1 
ATOM   1627 N N   . LYS A 1 216 ? 169.729 205.056 160.662 1.00 20.81 ? 244 LYS A N   1 
ATOM   1628 C CA  . LYS A 1 216 ? 169.907 206.035 161.728 1.00 20.81 ? 244 LYS A CA  1 
ATOM   1629 C C   . LYS A 1 216 ? 170.922 205.564 162.762 1.00 20.81 ? 244 LYS A C   1 
ATOM   1630 O O   . LYS A 1 216 ? 171.605 206.389 163.379 1.00 20.81 ? 244 LYS A O   1 
ATOM   1631 C CB  . LYS A 1 216 ? 168.564 206.331 162.395 1.00 20.81 ? 244 LYS A CB  1 
ATOM   1632 C CG  . LYS A 1 216 ? 168.614 207.421 163.454 1.00 20.81 ? 244 LYS A CG  1 
ATOM   1633 C CD  . LYS A 1 216 ? 167.252 207.630 164.101 1.00 20.81 ? 244 LYS A CD  1 
ATOM   1634 C CE  . LYS A 1 216 ? 166.265 208.251 163.126 1.00 20.81 ? 244 LYS A CE  1 
ATOM   1635 N NZ  . LYS A 1 216 ? 166.643 209.645 162.769 1.00 20.81 ? 244 LYS A NZ  1 
ATOM   1636 N N   . LEU A 1 217 ? 171.030 204.253 162.969 1.00 23.46 ? 245 LEU A N   1 
ATOM   1637 C CA  . LEU A 1 217 ? 171.942 203.690 163.959 1.00 23.46 ? 245 LEU A CA  1 
ATOM   1638 C C   . LEU A 1 217 ? 173.359 203.502 163.432 1.00 23.46 ? 245 LEU A C   1 
ATOM   1639 O O   . LEU A 1 217 ? 174.291 203.357 164.230 1.00 23.46 ? 245 LEU A O   1 
ATOM   1640 C CB  . LEU A 1 217 ? 171.385 202.349 164.457 1.00 23.46 ? 245 LEU A CB  1 
ATOM   1641 C CG  . LEU A 1 217 ? 172.182 201.427 165.376 1.00 23.46 ? 245 LEU A CG  1 
ATOM   1642 C CD1 . LEU A 1 217 ? 172.538 202.134 166.663 1.00 23.46 ? 245 LEU A CD1 1 
ATOM   1643 C CD2 . LEU A 1 217 ? 171.380 200.174 165.659 1.00 23.46 ? 245 LEU A CD2 1 
ATOM   1644 N N   . ASP A 1 218 ? 173.546 203.539 162.117 1.00 28.82 ? 246 ASP A N   1 
ATOM   1645 C CA  . ASP A 1 218 ? 174.833 203.254 161.484 1.00 28.82 ? 246 ASP A CA  1 
ATOM   1646 C C   . ASP A 1 218 ? 175.689 204.512 161.516 1.00 28.82 ? 246 ASP A C   1 
ATOM   1647 O O   . ASP A 1 218 ? 175.588 205.369 160.636 1.00 28.82 ? 246 ASP A O   1 
ATOM   1648 C CB  . ASP A 1 218 ? 174.616 202.771 160.057 1.00 28.82 ? 246 ASP A CB  1 
ATOM   1649 C CG  . ASP A 1 218 ? 175.816 202.069 159.499 1.00 28.82 ? 246 ASP A CG  1 
ATOM   1650 O OD1 . ASP A 1 218 ? 175.706 201.495 158.397 1.00 28.82 ? 246 ASP A OD1 1 
ATOM   1651 O OD2 . ASP A 1 218 ? 176.868 202.087 160.165 1.00 28.82 ? 246 ASP A OD2 1 
ATOM   1652 N N   . LEU A 1 219 ? 176.549 204.621 162.528 1.00 32.24 ? 247 LEU A N   1 
ATOM   1653 C CA  . LEU A 1 219 ? 177.376 205.816 162.667 1.00 32.24 ? 247 LEU A CA  1 
ATOM   1654 C C   . LEU A 1 219 ? 178.510 205.836 161.649 1.00 32.24 ? 247 LEU A C   1 
ATOM   1655 O O   . LEU A 1 219 ? 178.823 206.891 161.085 1.00 32.24 ? 247 LEU A O   1 
ATOM   1656 C CB  . LEU A 1 219 ? 177.935 205.907 164.087 1.00 32.24 ? 247 LEU A CB  1 
ATOM   1657 C CG  . LEU A 1 219 ? 177.142 206.707 165.124 1.00 32.24 ? 247 LEU A CG  1 
ATOM   1658 C CD1 . LEU A 1 219 ? 175.728 206.169 165.281 1.00 32.24 ? 247 LEU A CD1 1 
ATOM   1659 C CD2 . LEU A 1 219 ? 177.869 206.700 166.458 1.00 32.24 ? 247 LEU A CD2 1 
ATOM   1660 N N   . ASP A 1 220 ? 179.144 204.686 161.403 1.00 36.56 ? 248 ASP A N   1 
ATOM   1661 C CA  . ASP A 1 220 ? 180.328 204.666 160.550 1.00 36.56 ? 248 ASP A CA  1 
ATOM   1662 C C   . ASP A 1 220 ? 179.998 204.967 159.094 1.00 36.56 ? 248 ASP A C   1 
ATOM   1663 O O   . ASP A 1 220 ? 180.906 205.295 158.324 1.00 36.56 ? 248 ASP A O   1 
ATOM   1664 C CB  . ASP A 1 220 ? 181.063 203.319 160.676 1.00 36.56 ? 248 ASP A CB  1 
ATOM   1665 C CG  . ASP A 1 220 ? 180.201 202.116 160.297 1.00 36.56 ? 248 ASP A CG  1 
ATOM   1666 O OD1 . ASP A 1 220 ? 179.478 202.172 159.284 1.00 36.56 ? 248 ASP A OD1 1 
ATOM   1667 O OD2 . ASP A 1 220 ? 180.258 201.096 161.016 1.00 36.56 ? 248 ASP A OD2 1 
ATOM   1668 N N   . ASN A 1 221 ? 178.727 204.864 158.710 1.00 38.56 ? 249 ASN A N   1 
ATOM   1669 C CA  . ASN A 1 221 ? 178.282 205.128 157.344 1.00 38.56 ? 249 ASN A CA  1 
ATOM   1670 C C   . ASN A 1 221 ? 178.993 204.221 156.343 1.00 38.56 ? 249 ASN A C   1 
ATOM   1671 O O   . ASN A 1 221 ? 179.226 204.603 155.195 1.00 38.56 ? 249 ASN A O   1 
ATOM   1672 C CB  . ASN A 1 221 ? 178.471 206.602 156.975 1.00 38.56 ? 249 ASN A CB  1 
ATOM   1673 C CG  . ASN A 1 221 ? 177.602 207.029 155.810 1.00 38.56 ? 249 ASN A CG  1 
ATOM   1674 O OD1 . ASN A 1 221 ? 176.838 206.232 155.265 1.00 38.56 ? 249 ASN A OD1 1 
ATOM   1675 N ND2 . ASN A 1 221 ? 177.712 208.294 155.424 1.00 38.56 ? 249 ASN A ND2 1 
ATOM   1676 N N   . SER A 1 222 ? 179.349 203.015 156.778 1.00 36.39 ? 250 SER A N   1 
ATOM   1677 C CA  . SER A 1 222 ? 180.012 202.035 155.931 1.00 36.39 ? 250 SER A CA  1 
ATOM   1678 C C   . SER A 1 222 ? 179.071 200.951 155.425 1.00 36.39 ? 250 SER A C   1 
ATOM   1679 O O   . SER A 1 222 ? 179.519 200.045 154.717 1.00 36.39 ? 250 SER A O   1 
ATOM   1680 C CB  . SER A 1 222 ? 181.177 201.391 156.688 1.00 36.39 ? 250 SER A CB  1 
ATOM   1681 O OG  . SER A 1 222 ? 180.707 200.609 157.773 1.00 36.39 ? 250 SER A OG  1 
ATOM   1682 N N   . GLY A 1 223 ? 177.787 201.020 155.764 1.00 30.77 ? 251 GLY A N   1 
ATOM   1683 C CA  . GLY A 1 223 ? 176.846 199.998 155.360 1.00 30.77 ? 251 GLY A CA  1 
ATOM   1684 C C   . GLY A 1 223 ? 176.801 198.772 156.240 1.00 30.77 ? 251 GLY A C   1 
ATOM   1685 O O   . GLY A 1 223 ? 176.194 197.771 155.842 1.00 30.77 ? 251 GLY A O   1 
ATOM   1686 N N   . SER A 1 224 ? 177.424 198.808 157.419 1.00 28.52 ? 252 SER A N   1 
ATOM   1687 C CA  . SER A 1 224 ? 177.404 197.674 158.332 1.00 28.52 ? 252 SER A CA  1 
ATOM   1688 C C   . SER A 1 224 ? 177.618 198.154 159.761 1.00 28.52 ? 252 SER A C   1 
ATOM   1689 O O   . SER A 1 224 ? 178.312 199.145 160.003 1.00 28.52 ? 252 SER A O   1 
ATOM   1690 C CB  . SER A 1 224 ? 178.472 196.643 157.974 1.00 28.52 ? 252 SER A CB  1 
ATOM   1691 O OG  . SER A 1 224 ? 179.766 197.142 158.257 1.00 28.52 ? 252 SER A OG  1 
ATOM   1692 N N   . LEU A 1 225 ? 177.033 197.417 160.704 1.00 27.15 ? 253 LEU A N   1 
ATOM   1693 C CA  . LEU A 1 225 ? 177.079 197.750 162.123 1.00 27.15 ? 253 LEU A CA  1 
ATOM   1694 C C   . LEU A 1 225 ? 178.172 196.945 162.814 1.00 27.15 ? 253 LEU A C   1 
ATOM   1695 O O   . LEU A 1 225 ? 178.187 195.712 162.733 1.00 27.15 ? 253 LEU A O   1 
ATOM   1696 C CB  . LEU A 1 225 ? 175.734 197.460 162.790 1.00 27.15 ? 253 LEU A CB  1 
ATOM   1697 C CG  . LEU A 1 225 ? 174.512 198.243 162.332 1.00 27.15 ? 253 LEU A CG  1 
ATOM   1698 C CD1 . LEU A 1 225 ? 173.279 197.770 163.072 1.00 27.15 ? 253 LEU A CD1 1 
ATOM   1699 C CD2 . LEU A 1 225 ? 174.743 199.716 162.563 1.00 27.15 ? 253 LEU A CD2 1 
ATOM   1700 N N   . SER A 1 226 ? 179.074 197.637 163.501 1.00 25.23 ? 254 SER A N   1 
ATOM   1701 C CA  . SER A 1 226 ? 180.092 196.995 164.315 1.00 25.23 ? 254 SER A CA  1 
ATOM   1702 C C   . SER A 1 226 ? 179.655 197.019 165.774 1.00 25.23 ? 254 SER A C   1 
ATOM   1703 O O   . SER A 1 226 ? 178.618 197.585 166.128 1.00 25.23 ? 254 SER A O   1 
ATOM   1704 C CB  . SER A 1 226 ? 181.448 197.675 164.132 1.00 25.23 ? 254 SER A CB  1 
ATOM   1705 O OG  . SER A 1 226 ? 181.511 198.885 164.860 1.00 25.23 ? 254 SER A OG  1 
ATOM   1706 N N   . VAL A 1 227 ? 180.463 196.394 166.630 1.00 24.65 ? 255 VAL A N   1 
ATOM   1707 C CA  . VAL A 1 227 ? 180.089 196.240 168.032 1.00 24.65 ? 255 VAL A CA  1 
ATOM   1708 C C   . VAL A 1 227 ? 180.131 197.582 168.757 1.00 24.65 ? 255 VAL A C   1 
ATOM   1709 O O   . VAL A 1 227 ? 179.272 197.881 169.603 1.00 24.65 ? 255 VAL A O   1 
ATOM   1710 C CB  . VAL A 1 227 ? 180.998 195.193 168.697 1.00 24.65 ? 255 VAL A CB  1 
ATOM   1711 C CG1 . VAL A 1 227 ? 180.774 195.161 170.175 1.00 24.65 ? 255 VAL A CG1 1 
ATOM   1712 C CG2 . VAL A 1 227 ? 180.734 193.827 168.100 1.00 24.65 ? 255 VAL A CG2 1 
ATOM   1713 N N   . GLU A 1 228 ? 181.119 198.418 168.432 1.00 27.25 ? 256 GLU A N   1 
ATOM   1714 C CA  . GLU A 1 228 ? 181.213 199.724 169.074 1.00 27.25 ? 256 GLU A CA  1 
ATOM   1715 C C   . GLU A 1 228 ? 179.998 200.579 168.750 1.00 27.25 ? 256 GLU A C   1 
ATOM   1716 O O   . GLU A 1 228 ? 179.599 201.422 169.560 1.00 27.25 ? 256 GLU A O   1 
ATOM   1717 C CB  . GLU A 1 228 ? 182.519 200.408 168.655 1.00 27.25 ? 256 GLU A CB  1 
ATOM   1718 C CG  . GLU A 1 228 ? 182.918 201.664 169.441 1.00 27.25 ? 256 GLU A CG  1 
ATOM   1719 C CD  . GLU A 1 228 ? 182.118 202.907 169.099 1.00 27.25 ? 256 GLU A CD  1 
ATOM   1720 O OE1 . GLU A 1 228 ? 182.246 203.908 169.832 1.00 27.25 ? 256 GLU A OE1 1 
ATOM   1721 O OE2 . GLU A 1 228 ? 181.410 202.910 168.073 1.00 27.25 ? 256 GLU A OE2 1 
ATOM   1722 N N   . GLU A 1 229 ? 179.383 200.367 167.586 1.00 25.11 ? 257 GLU A N   1 
ATOM   1723 C CA  . GLU A 1 229 ? 178.169 201.104 167.262 1.00 25.11 ? 257 GLU A CA  1 
ATOM   1724 C C   . GLU A 1 229 ? 176.990 200.627 168.098 1.00 25.11 ? 257 GLU A C   1 
ATOM   1725 O O   . GLU A 1 229 ? 176.113 201.423 168.448 1.00 25.11 ? 257 GLU A O   1 
ATOM   1726 C CB  . GLU A 1 229 ? 177.857 200.986 165.771 1.00 25.11 ? 257 GLU A CB  1 
ATOM   1727 C CG  . GLU A 1 229 ? 179.079 201.013 164.865 1.00 25.11 ? 257 GLU A CG  1 
ATOM   1728 C CD  . GLU A 1 229 ? 179.750 202.377 164.791 1.00 25.11 ? 257 GLU A CD  1 
ATOM   1729 O OE1 . GLU A 1 229 ? 179.268 203.328 165.440 1.00 25.11 ? 257 GLU A OE1 1 
ATOM   1730 O OE2 . GLU A 1 229 ? 180.767 202.497 164.075 1.00 25.11 ? 257 GLU A OE2 1 
ATOM   1731 N N   . PHE A 1 230 ? 176.936 199.333 168.423 1.00 18.68 ? 258 PHE A N   1 
ATOM   1732 C CA  . PHE A 1 230 ? 175.890 198.863 169.324 1.00 18.68 ? 258 PHE A CA  1 
ATOM   1733 C C   . PHE A 1 230 ? 176.080 199.304 170.769 1.00 18.68 ? 258 PHE A C   1 
ATOM   1734 O O   . PHE A 1 230 ? 175.113 199.365 171.535 1.00 18.68 ? 258 PHE A O   1 
ATOM   1735 C CB  . PHE A 1 230 ? 175.840 197.341 169.371 1.00 18.68 ? 258 PHE A CB  1 
ATOM   1736 C CG  . PHE A 1 230 ? 174.991 196.739 168.309 1.00 18.68 ? 258 PHE A CG  1 
ATOM   1737 C CD1 . PHE A 1 230 ? 173.896 195.971 168.648 1.00 18.68 ? 258 PHE A CD1 1 
ATOM   1738 C CD2 . PHE A 1 230 ? 175.295 196.908 166.982 1.00 18.68 ? 258 PHE A CD2 1 
ATOM   1739 C CE1 . PHE A 1 230 ? 173.103 195.404 167.681 1.00 18.68 ? 258 PHE A CE1 1 
ATOM   1740 C CE2 . PHE A 1 230 ? 174.509 196.336 166.008 1.00 18.68 ? 258 PHE A CE2 1 
ATOM   1741 C CZ  . PHE A 1 230 ? 173.410 195.583 166.359 1.00 18.68 ? 258 PHE A CZ  1 
ATOM   1742 N N   . MET A 1 231 ? 177.314 199.621 171.169 1.00 19.49 ? 259 MET A N   1 
ATOM   1743 C CA  . MET A 1 231 ? 177.406 200.099 172.550 1.00 19.49 ? 259 MET A CA  1 
ATOM   1744 C C   . MET A 1 231 ? 177.289 201.614 172.528 1.00 19.49 ? 259 MET A C   1 
ATOM   1745 O O   . MET A 1 231 ? 177.629 202.248 173.533 1.00 19.49 ? 259 MET A O   1 
ATOM   1746 C CB  . MET A 1 231 ? 178.692 199.723 173.283 1.00 19.49 ? 259 MET A CB  1 
ATOM   1747 C CG  . MET A 1 231 ? 178.578 198.468 174.127 1.00 19.49 ? 259 MET A CG  1 
ATOM   1748 S SD  . MET A 1 231 ? 178.584 196.901 173.261 1.00 19.49 ? 259 MET A SD  1 
ATOM   1749 C CE  . MET A 1 231 ? 180.350 196.632 173.221 1.00 19.49 ? 259 MET A CE  1 
ATOM   1750 N N   . SER A 1 232 ? 176.832 202.216 171.430 1.00 17.84 ? 260 SER A N   1 
ATOM   1751 C CA  . SER A 1 232 ? 176.534 203.643 171.453 1.00 17.84 ? 260 SER A CA  1 
ATOM   1752 C C   . SER A 1 232 ? 175.266 203.921 172.245 1.00 17.84 ? 260 SER A C   1 
ATOM   1753 O O   . SER A 1 232 ? 175.126 204.986 172.856 1.00 17.84 ? 260 SER A O   1 
ATOM   1754 C CB  . SER A 1 232 ? 176.401 204.178 170.030 1.00 17.84 ? 260 SER A CB  1 
ATOM   1755 O OG  . SER A 1 232 ? 176.264 205.586 170.035 1.00 17.84 ? 260 SER A OG  1 
ATOM   1756 N N   . LEU A 1 233 ? 174.336 202.978 172.247 1.00 16.63 ? 261 LEU A N   1 
ATOM   1757 C CA  . LEU A 1 233 ? 173.065 203.161 172.938 1.00 16.63 ? 261 LEU A CA  1 
ATOM   1758 C C   . LEU A 1 233 ? 173.295 203.165 174.443 1.00 16.63 ? 261 LEU A C   1 
ATOM   1759 O O   . LEU A 1 233 ? 173.737 202.151 174.992 1.00 16.63 ? 261 LEU A O   1 
ATOM   1760 C CB  . LEU A 1 233 ? 172.101 202.050 172.547 1.00 16.63 ? 261 LEU A CB  1 
ATOM   1761 C CG  . LEU A 1 233 ? 171.100 202.348 171.432 1.00 16.63 ? 261 LEU A CG  1 
ATOM   1762 C CD1 . LEU A 1 233 ? 171.796 202.821 170.180 1.00 16.63 ? 261 LEU A CD1 1 
ATOM   1763 C CD2 . LEU A 1 233 ? 170.298 201.106 171.132 1.00 16.63 ? 261 LEU A CD2 1 
ATOM   1764 N N   . PRO A 1 234 ? 172.987 204.254 175.148 1.00 16.18 ? 262 PRO A N   1 
ATOM   1765 C CA  . PRO A 1 234 ? 173.401 204.356 176.555 1.00 16.18 ? 262 PRO A CA  1 
ATOM   1766 C C   . PRO A 1 234 ? 172.789 203.309 177.466 1.00 16.18 ? 262 PRO A C   1 
ATOM   1767 O O   . PRO A 1 234 ? 173.349 203.056 178.538 1.00 16.18 ? 262 PRO A O   1 
ATOM   1768 C CB  . PRO A 1 234 ? 172.957 205.770 176.950 1.00 16.18 ? 262 PRO A CB  1 
ATOM   1769 C CG  . PRO A 1 234 ? 171.916 206.141 175.960 1.00 16.18 ? 262 PRO A CG  1 
ATOM   1770 C CD  . PRO A 1 234 ? 172.304 205.469 174.683 1.00 16.18 ? 262 PRO A CD  1 
ATOM   1771 N N   . GLU A 1 235 ? 171.669 202.693 177.094 1.00 17.05 ? 263 GLU A N   1 
ATOM   1772 C CA  . GLU A 1 235 ? 171.056 201.668 177.928 1.00 17.05 ? 263 GLU A CA  1 
ATOM   1773 C C   . GLU A 1 235 ? 171.239 200.270 177.352 1.00 17.05 ? 263 GLU A C   1 
ATOM   1774 O O   . GLU A 1 235 ? 170.635 199.313 177.846 1.00 17.05 ? 263 GLU A O   1 
ATOM   1775 C CB  . GLU A 1 235 ? 169.574 201.981 178.147 1.00 17.05 ? 263 GLU A CB  1 
ATOM   1776 C CG  . GLU A 1 235 ? 168.940 201.232 179.315 1.00 17.05 ? 263 GLU A CG  1 
ATOM   1777 C CD  . GLU A 1 235 ? 169.610 201.530 180.643 1.00 17.05 ? 263 GLU A CD  1 
ATOM   1778 O OE1 . GLU A 1 235 ? 170.134 202.650 180.814 1.00 17.05 ? 263 GLU A OE1 1 
ATOM   1779 O OE2 . GLU A 1 235 ? 169.621 200.636 181.515 1.00 17.05 ? 263 GLU A OE2 1 
ATOM   1780 N N   . LEU A 1 236 ? 172.068 200.126 176.325 1.00 14.83 ? 264 LEU A N   1 
ATOM   1781 C CA  . LEU A 1 236 ? 172.409 198.822 175.783 1.00 14.83 ? 264 LEU A CA  1 
ATOM   1782 C C   . LEU A 1 236 ? 173.795 198.357 176.210 1.00 14.83 ? 264 LEU A C   1 
ATOM   1783 O O   . LEU A 1 236 ? 174.105 197.171 176.072 1.00 14.83 ? 264 LEU A O   1 
ATOM   1784 C CB  . LEU A 1 236 ? 172.312 198.861 174.253 1.00 14.83 ? 264 LEU A CB  1 
ATOM   1785 C CG  . LEU A 1 236 ? 172.384 197.584 173.423 1.00 14.83 ? 264 LEU A CG  1 
ATOM   1786 C CD1 . LEU A 1 236 ? 171.505 197.740 172.211 1.00 14.83 ? 264 LEU A CD1 1 
ATOM   1787 C CD2 . LEU A 1 236 ? 173.801 197.320 172.986 1.00 14.83 ? 264 LEU A CD2 1 
ATOM   1788 N N   . GLN A 1 237 ? 174.621 199.254 176.751 1.00 15.95 ? 265 GLN A N   1 
ATOM   1789 C CA  . GLN A 1 237 ? 175.999 198.899 177.066 1.00 15.95 ? 265 GLN A CA  1 
ATOM   1790 C C   . GLN A 1 237 ? 176.083 198.007 178.296 1.00 15.95 ? 265 GLN A C   1 
ATOM   1791 O O   . GLN A 1 237 ? 176.860 197.046 178.318 1.00 15.95 ? 265 GLN A O   1 
ATOM   1792 C CB  . GLN A 1 237 ? 176.825 200.163 177.272 1.00 15.95 ? 265 GLN A CB  1 
ATOM   1793 C CG  . GLN A 1 237 ? 176.156 201.183 178.161 1.00 15.95 ? 265 GLN A CG  1 
ATOM   1794 C CD  . GLN A 1 237 ? 177.072 202.329 178.511 1.00 15.95 ? 265 GLN A CD  1 
ATOM   1795 O OE1 . GLN A 1 237 ? 177.994 202.650 177.763 1.00 15.95 ? 265 GLN A OE1 1 
ATOM   1796 N NE2 . GLN A 1 237 ? 176.824 202.956 179.653 1.00 15.95 ? 265 GLN A NE2 1 
ATOM   1797 N N   . GLN A 1 238 ? 175.293 198.303 179.328 1.00 13.61 ? 266 GLN A N   1 
ATOM   1798 C CA  . GLN A 1 238 ? 175.401 197.573 180.585 1.00 13.61 ? 266 GLN A CA  1 
ATOM   1799 C C   . GLN A 1 238 ? 174.888 196.142 180.489 1.00 13.61 ? 266 GLN A C   1 
ATOM   1800 O O   . GLN A 1 238 ? 175.100 195.363 181.424 1.00 13.61 ? 266 GLN A O   1 
ATOM   1801 C CB  . GLN A 1 238 ? 174.657 198.334 181.686 1.00 13.61 ? 266 GLN A CB  1 
ATOM   1802 C CG  . GLN A 1 238 ? 174.993 197.896 183.104 1.00 13.61 ? 266 GLN A CG  1 
ATOM   1803 C CD  . GLN A 1 238 ? 176.445 198.129 183.482 1.00 13.61 ? 266 GLN A CD  1 
ATOM   1804 O OE1 . GLN A 1 238 ? 177.195 198.788 182.763 1.00 13.61 ? 266 GLN A OE1 1 
ATOM   1805 N NE2 . GLN A 1 238 ? 176.847 197.582 184.623 1.00 13.61 ? 266 GLN A NE2 1 
ATOM   1806 N N   . ASN A 1 239 ? 174.241 195.777 179.392 1.00 9.47  ? 267 ASN A N   1 
ATOM   1807 C CA  . ASN A 1 239 ? 173.754 194.418 179.228 1.00 9.47  ? 267 ASN A CA  1 
ATOM   1808 C C   . ASN A 1 239 ? 174.921 193.436 179.280 1.00 9.47  ? 267 ASN A C   1 
ATOM   1809 O O   . ASN A 1 239 ? 175.939 193.658 178.611 1.00 9.47  ? 267 ASN A O   1 
ATOM   1810 C CB  . ASN A 1 239 ? 173.018 194.283 177.901 1.00 9.47  ? 267 ASN A CB  1 
ATOM   1811 C CG  . ASN A 1 239 ? 171.873 193.322 177.975 1.00 9.47  ? 267 ASN A CG  1 
ATOM   1812 O OD1 . ASN A 1 239 ? 171.625 192.725 179.012 1.00 9.47  ? 267 ASN A OD1 1 
ATOM   1813 N ND2 . ASN A 1 239 ? 171.178 193.146 176.871 1.00 9.47  ? 267 ASN A ND2 1 
ATOM   1814 N N   . PRO A 1 240 ? 174.834 192.369 180.080 1.00 11.57 ? 268 PRO A N   1 
ATOM   1815 C CA  . PRO A 1 240 ? 175.881 191.338 180.056 1.00 11.57 ? 268 PRO A CA  1 
ATOM   1816 C C   . PRO A 1 240 ? 175.970 190.598 178.732 1.00 11.57 ? 268 PRO A C   1 
ATOM   1817 O O   . PRO A 1 240 ? 177.039 190.539 178.117 1.00 11.57 ? 268 PRO A O   1 
ATOM   1818 C CB  . PRO A 1 240 ? 175.461 190.390 181.184 1.00 11.57 ? 268 PRO A CB  1 
ATOM   1819 C CG  . PRO A 1 240 ? 174.629 191.215 182.080 1.00 11.57 ? 268 PRO A CG  1 
ATOM   1820 C CD  . PRO A 1 240 ? 173.895 192.167 181.193 1.00 11.57 ? 268 PRO A CD  1 
ATOM   1821 N N   . LEU A 1 241 ? 174.855 190.023 178.290 1.00 8.74  ? 269 LEU A N   1 
ATOM   1822 C CA  . LEU A 1 241 ? 174.848 189.155 177.115 1.00 8.74  ? 269 LEU A CA  1 
ATOM   1823 C C   . LEU A 1 241 ? 174.420 189.929 175.866 1.00 8.74  ? 269 LEU A C   1 
ATOM   1824 O O   . LEU A 1 241 ? 173.504 189.563 175.141 1.00 8.74  ? 269 LEU A O   1 
ATOM   1825 C CB  . LEU A 1 241 ? 173.975 187.927 177.387 1.00 8.74  ? 269 LEU A CB  1 
ATOM   1826 C CG  . LEU A 1 241 ? 172.476 187.986 177.717 1.00 8.74  ? 269 LEU A CG  1 
ATOM   1827 C CD1 . LEU A 1 241 ? 171.572 188.012 176.512 1.00 8.74  ? 269 LEU A CD1 1 
ATOM   1828 C CD2 . LEU A 1 241 ? 172.071 186.854 178.616 1.00 8.74  ? 269 LEU A CD2 1 
ATOM   1829 N N   . VAL A 1 242 ? 175.150 191.000 175.578 1.00 10.84 ? 270 VAL A N   1 
ATOM   1830 C CA  . VAL A 1 242 ? 175.018 191.677 174.295 1.00 10.84 ? 270 VAL A CA  1 
ATOM   1831 C C   . VAL A 1 242 ? 175.946 191.072 173.251 1.00 10.84 ? 270 VAL A C   1 
ATOM   1832 O O   . VAL A 1 242 ? 175.510 190.763 172.141 1.00 10.84 ? 270 VAL A O   1 
ATOM   1833 C CB  . VAL A 1 242 ? 175.237 193.201 174.434 1.00 10.84 ? 270 VAL A CB  1 
ATOM   1834 C CG1 . VAL A 1 242 ? 176.650 193.535 174.864 1.00 10.84 ? 270 VAL A CG1 1 
ATOM   1835 C CG2 . VAL A 1 242 ? 174.936 193.882 173.124 1.00 10.84 ? 270 VAL A CG2 1 
ATOM   1836 N N   . GLN A 1 243 ? 177.207 190.836 173.616 1.00 11.83 ? 271 GLN A N   1 
ATOM   1837 C CA  . GLN A 1 243 ? 178.176 190.301 172.671 1.00 11.83 ? 271 GLN A CA  1 
ATOM   1838 C C   . GLN A 1 243 ? 177.656 189.026 172.034 1.00 11.83 ? 271 GLN A C   1 
ATOM   1839 O O   . GLN A 1 243 ? 177.642 188.892 170.806 1.00 11.83 ? 271 GLN A O   1 
ATOM   1840 C CB  . GLN A 1 243 ? 179.501 190.040 173.379 1.00 11.83 ? 271 GLN A CB  1 
ATOM   1841 C CG  . GLN A 1 243 ? 180.613 189.658 172.446 1.00 11.83 ? 271 GLN A CG  1 
ATOM   1842 C CD  . GLN A 1 243 ? 181.081 190.825 171.615 1.00 11.83 ? 271 GLN A CD  1 
ATOM   1843 O OE1 . GLN A 1 243 ? 181.254 191.930 172.127 1.00 11.83 ? 271 GLN A OE1 1 
ATOM   1844 N NE2 . GLN A 1 243 ? 181.282 190.592 170.324 1.00 11.83 ? 271 GLN A NE2 1 
ATOM   1845 N N   . ARG A 1 244 ? 177.166 188.101 172.860 1.00 13.20 ? 272 ARG A N   1 
ATOM   1846 C CA  . ARG A 1 244 ? 176.652 186.839 172.345 1.00 13.20 ? 272 ARG A CA  1 
ATOM   1847 C C   . ARG A 1 244 ? 175.619 187.071 171.252 1.00 13.20 ? 272 ARG A C   1 
ATOM   1848 O O   . ARG A 1 244 ? 175.688 186.462 170.179 1.00 13.20 ? 272 ARG A O   1 
ATOM   1849 C CB  . ARG A 1 244 ? 176.052 186.012 173.479 1.00 13.20 ? 272 ARG A CB  1 
ATOM   1850 C CG  . ARG A 1 244 ? 177.072 185.280 174.322 1.00 13.20 ? 272 ARG A CG  1 
ATOM   1851 C CD  . ARG A 1 244 ? 178.011 184.440 173.471 1.00 13.20 ? 272 ARG A CD  1 
ATOM   1852 N NE  . ARG A 1 244 ? 177.303 183.565 172.544 1.00 13.20 ? 272 ARG A NE  1 
ATOM   1853 C CZ  . ARG A 1 244 ? 177.806 183.146 171.388 1.00 13.20 ? 272 ARG A CZ  1 
ATOM   1854 N NH1 . ARG A 1 244 ? 179.019 183.526 171.016 1.00 13.20 ? 272 ARG A NH1 1 
ATOM   1855 N NH2 . ARG A 1 244 ? 177.097 182.351 170.602 1.00 13.20 ? 272 ARG A NH2 1 
ATOM   1856 N N   . VAL A 1 245 ? 174.675 187.983 171.486 1.00 13.54 ? 273 VAL A N   1 
ATOM   1857 C CA  . VAL A 1 245 ? 173.609 188.170 170.508 1.00 13.54 ? 273 VAL A CA  1 
ATOM   1858 C C   . VAL A 1 245 ? 174.173 188.708 169.202 1.00 13.54 ? 273 VAL A C   1 
ATOM   1859 O O   . VAL A 1 245 ? 173.722 188.329 168.115 1.00 13.54 ? 273 VAL A O   1 
ATOM   1860 C CB  . VAL A 1 245 ? 172.503 189.077 171.067 1.00 13.54 ? 273 VAL A CB  1 
ATOM   1861 C CG1 . VAL A 1 245 ? 171.324 189.093 170.121 1.00 13.54 ? 273 VAL A CG1 1 
ATOM   1862 C CG2 . VAL A 1 245 ? 172.068 188.583 172.423 1.00 13.54 ? 273 VAL A CG2 1 
ATOM   1863 N N   . ILE A 1 246 ? 175.186 189.574 169.279 1.00 13.57 ? 274 ILE A N   1 
ATOM   1864 C CA  . ILE A 1 246 ? 175.827 190.030 168.051 1.00 13.57 ? 274 ILE A CA  1 
ATOM   1865 C C   . ILE A 1 246 ? 176.350 188.836 167.270 1.00 13.57 ? 274 ILE A C   1 
ATOM   1866 O O   . ILE A 1 246 ? 176.129 188.718 166.059 1.00 13.57 ? 274 ILE A O   1 
ATOM   1867 C CB  . ILE A 1 246 ? 176.950 191.032 168.363 1.00 13.57 ? 274 ILE A CB  1 
ATOM   1868 C CG1 . ILE A 1 246 ? 176.400 192.191 169.174 1.00 13.57 ? 274 ILE A CG1 1 
ATOM   1869 C CG2 . ILE A 1 246 ? 177.563 191.548 167.081 1.00 13.57 ? 274 ILE A CG2 1 
ATOM   1870 C CD1 . ILE A 1 246 ? 175.262 192.855 168.507 1.00 13.57 ? 274 ILE A CD1 1 
ATOM   1871 N N   . ASP A 1 247 ? 176.996 187.900 167.963 1.00 14.41 ? 275 ASP A N   1 
ATOM   1872 C CA  . ASP A 1 247 ? 177.559 186.740 167.297 1.00 14.41 ? 275 ASP A CA  1 
ATOM   1873 C C   . ASP A 1 247 ? 176.494 185.786 166.788 1.00 14.41 ? 275 ASP A C   1 
ATOM   1874 O O   . ASP A 1 247 ? 176.830 184.849 166.062 1.00 14.41 ? 275 ASP A O   1 
ATOM   1875 C CB  . ASP A 1 247 ? 178.507 186.011 168.241 1.00 14.41 ? 275 ASP A CB  1 
ATOM   1876 C CG  . ASP A 1 247 ? 179.796 186.770 168.468 1.00 14.41 ? 275 ASP A CG  1 
ATOM   1877 O OD1 . ASP A 1 247 ? 180.787 186.147 168.899 1.00 14.41 ? 275 ASP A OD1 1 
ATOM   1878 O OD2 . ASP A 1 247 ? 179.818 187.992 168.217 1.00 14.41 ? 275 ASP A OD2 1 
ATOM   1879 N N   . ILE A 1 248 ? 175.232 185.986 167.155 1.00 18.15 ? 276 ILE A N   1 
ATOM   1880 C CA  . ILE A 1 248 ? 174.155 185.227 166.529 1.00 18.15 ? 276 ILE A CA  1 
ATOM   1881 C C   . ILE A 1 248 ? 173.652 185.928 165.276 1.00 18.15 ? 276 ILE A C   1 
ATOM   1882 O O   . ILE A 1 248 ? 173.221 185.275 164.323 1.00 18.15 ? 276 ILE A O   1 
ATOM   1883 C CB  . ILE A 1 248 ? 173.013 184.992 167.533 1.00 18.15 ? 276 ILE A CB  1 
ATOM   1884 C CG1 . ILE A 1 248 ? 173.566 184.454 168.848 1.00 18.15 ? 276 ILE A CG1 1 
ATOM   1885 C CG2 . ILE A 1 248 ? 171.996 184.034 166.955 1.00 18.15 ? 276 ILE A CG2 1 
ATOM   1886 C CD1 . ILE A 1 248 ? 174.050 183.037 168.761 1.00 18.15 ? 276 ILE A CD1 1 
ATOM   1887 N N   . PHE A 1 249 ? 173.700 187.263 165.261 1.00 19.25 ? 277 PHE A N   1 
ATOM   1888 C CA  . PHE A 1 249 ? 173.296 188.003 164.071 1.00 19.25 ? 277 PHE A CA  1 
ATOM   1889 C C   . PHE A 1 249 ? 174.371 187.935 162.997 1.00 19.25 ? 277 PHE A C   1 
ATOM   1890 O O   . PHE A 1 249 ? 174.067 187.962 161.800 1.00 19.25 ? 277 PHE A O   1 
ATOM   1891 C CB  . PHE A 1 249 ? 173.001 189.457 164.430 1.00 19.25 ? 277 PHE A CB  1 
ATOM   1892 C CG  . PHE A 1 249 ? 171.649 189.673 165.038 1.00 19.25 ? 277 PHE A CG  1 
ATOM   1893 C CD1 . PHE A 1 249 ? 170.872 188.602 165.438 1.00 19.25 ? 277 PHE A CD1 1 
ATOM   1894 C CD2 . PHE A 1 249 ? 171.148 190.950 165.198 1.00 19.25 ? 277 PHE A CD2 1 
ATOM   1895 C CE1 . PHE A 1 249 ? 169.629 188.803 165.994 1.00 19.25 ? 277 PHE A CE1 1 
ATOM   1896 C CE2 . PHE A 1 249 ? 169.906 191.155 165.750 1.00 19.25 ? 277 PHE A CE2 1 
ATOM   1897 C CZ  . PHE A 1 249 ? 169.145 190.079 166.147 1.00 19.25 ? 277 PHE A CZ  1 
ATOM   1898 N N   . ASP A 1 250 ? 175.632 187.836 163.411 1.00 25.98 ? 278 ASP A N   1 
ATOM   1899 C CA  . ASP A 1 250 ? 176.784 187.909 162.517 1.00 25.98 ? 278 ASP A CA  1 
ATOM   1900 C C   . ASP A 1 250 ? 177.022 186.544 161.870 1.00 25.98 ? 278 ASP A C   1 
ATOM   1901 O O   . ASP A 1 250 ? 178.048 185.890 162.065 1.00 25.98 ? 278 ASP A O   1 
ATOM   1902 C CB  . ASP A 1 250 ? 177.997 188.375 163.305 1.00 25.98 ? 278 ASP A CB  1 
ATOM   1903 C CG  . ASP A 1 250 ? 179.079 188.934 162.434 1.00 25.98 ? 278 ASP A CG  1 
ATOM   1904 O OD1 . ASP A 1 250 ? 178.829 189.130 161.230 1.00 25.98 ? 278 ASP A OD1 1 
ATOM   1905 O OD2 . ASP A 1 250 ? 180.182 189.183 162.960 1.00 25.98 ? 278 ASP A OD2 1 
ATOM   1906 N N   . THR A 1 251 ? 176.043 186.116 161.070 1.00 30.12 ? 279 THR A N   1 
ATOM   1907 C CA  . THR A 1 251 ? 176.078 184.759 160.532 1.00 30.12 ? 279 THR A CA  1 
ATOM   1908 C C   . THR A 1 251 ? 177.097 184.606 159.410 1.00 30.12 ? 279 THR A C   1 
ATOM   1909 O O   . THR A 1 251 ? 177.463 183.478 159.061 1.00 30.12 ? 279 THR A O   1 
ATOM   1910 C CB  . THR A 1 251 ? 174.698 184.346 160.028 1.00 30.12 ? 279 THR A CB  1 
ATOM   1911 O OG1 . THR A 1 251 ? 174.723 182.960 159.669 1.00 30.12 ? 279 THR A OG1 1 
ATOM   1912 C CG2 . THR A 1 251 ? 174.311 185.159 158.808 1.00 30.12 ? 279 THR A CG2 1 
ATOM   1913 N N   . ASP A 1 252 ? 177.554 185.709 158.824 1.00 31.06 ? 280 ASP A N   1 
ATOM   1914 C CA  . ASP A 1 252 ? 178.545 185.639 157.759 1.00 31.06 ? 280 ASP A CA  1 
ATOM   1915 C C   . ASP A 1 252 ? 179.982 185.615 158.269 1.00 31.06 ? 280 ASP A C   1 
ATOM   1916 O O   . ASP A 1 252 ? 180.896 185.374 157.476 1.00 31.06 ? 280 ASP A O   1 
ATOM   1917 C CB  . ASP A 1 252 ? 178.336 186.803 156.782 1.00 31.06 ? 280 ASP A CB  1 
ATOM   1918 C CG  . ASP A 1 252 ? 178.363 188.161 157.466 1.00 31.06 ? 280 ASP A CG  1 
ATOM   1919 O OD1 . ASP A 1 252 ? 178.472 188.206 158.706 1.00 31.06 ? 280 ASP A OD1 1 
ATOM   1920 O OD2 . ASP A 1 252 ? 178.259 189.186 156.763 1.00 31.06 ? 280 ASP A OD2 1 
ATOM   1921 N N   . GLY A 1 253 ? 180.205 185.856 159.559 1.00 26.27 ? 281 GLY A N   1 
ATOM   1922 C CA  . GLY A 1 253 ? 181.521 185.731 160.149 1.00 26.27 ? 281 GLY A CA  1 
ATOM   1923 C C   . GLY A 1 253 ? 182.478 186.864 159.859 1.00 26.27 ? 281 GLY A C   1 
ATOM   1924 O O   . GLY A 1 253 ? 183.632 186.801 160.297 1.00 26.27 ? 281 GLY A O   1 
ATOM   1925 N N   . ASN A 1 254 ? 182.043 187.903 159.151 1.00 30.81 ? 282 ASN A N   1 
ATOM   1926 C CA  . ASN A 1 254 ? 182.936 188.982 158.753 1.00 30.81 ? 282 ASN A CA  1 
ATOM   1927 C C   . ASN A 1 254 ? 183.194 189.993 159.861 1.00 30.81 ? 282 ASN A C   1 
ATOM   1928 O O   . ASN A 1 254 ? 184.042 190.874 159.683 1.00 30.81 ? 282 ASN A O   1 
ATOM   1929 C CB  . ASN A 1 254 ? 182.366 189.704 157.532 1.00 30.81 ? 282 ASN A CB  1 
ATOM   1930 C CG  . ASN A 1 254 ? 180.928 190.148 157.734 1.00 30.81 ? 282 ASN A CG  1 
ATOM   1931 O OD1 . ASN A 1 254 ? 180.414 190.146 158.852 1.00 30.81 ? 282 ASN A OD1 1 
ATOM   1932 N ND2 . ASN A 1 254 ? 180.269 190.526 156.647 1.00 30.81 ? 282 ASN A ND2 1 
ATOM   1933 N N   . GLY A 1 255 ? 182.492 189.894 160.987 1.00 31.49 ? 283 GLY A N   1 
ATOM   1934 C CA  . GLY A 1 255 ? 182.605 190.868 162.051 1.00 31.49 ? 283 GLY A CA  1 
ATOM   1935 C C   . GLY A 1 255 ? 181.638 192.029 161.968 1.00 31.49 ? 283 GLY A C   1 
ATOM   1936 O O   . GLY A 1 255 ? 181.656 192.893 162.853 1.00 31.49 ? 283 GLY A O   1 
ATOM   1937 N N   . GLU A 1 256 ? 180.793 192.079 160.942 1.00 32.90 ? 284 GLU A N   1 
ATOM   1938 C CA  . GLU A 1 256 ? 179.887 193.195 160.731 1.00 32.90 ? 284 GLU A CA  1 
ATOM   1939 C C   . GLU A 1 256 ? 178.478 192.680 160.480 1.00 32.90 ? 284 GLU A C   1 
ATOM   1940 O O   . GLU A 1 256 ? 178.283 191.596 159.922 1.00 32.90 ? 284 GLU A O   1 
ATOM   1941 C CB  . GLU A 1 256 ? 180.338 194.069 159.549 1.00 32.90 ? 284 GLU A CB  1 
ATOM   1942 C CG  . GLU A 1 256 ? 180.107 193.433 158.181 1.00 32.90 ? 284 GLU A CG  1 
ATOM   1943 C CD  . GLU A 1 256 ? 180.695 194.240 157.039 1.00 32.90 ? 284 GLU A CD  1 
ATOM   1944 O OE1 . GLU A 1 256 ? 181.311 195.292 157.305 1.00 32.90 ? 284 GLU A OE1 1 
ATOM   1945 O OE2 . GLU A 1 256 ? 180.537 193.822 155.873 1.00 32.90 ? 284 GLU A OE2 1 
ATOM   1946 N N   . VAL A 1 257 ? 177.494 193.470 160.904 1.00 24.16 ? 285 VAL A N   1 
ATOM   1947 C CA  . VAL A 1 257 ? 176.084 193.179 160.682 1.00 24.16 ? 285 VAL A CA  1 
ATOM   1948 C C   . VAL A 1 257 ? 175.556 194.197 159.684 1.00 24.16 ? 285 VAL A C   1 
ATOM   1949 O O   . VAL A 1 257 ? 175.778 195.402 159.848 1.00 24.16 ? 285 VAL A O   1 
ATOM   1950 C CB  . VAL A 1 257 ? 175.283 193.228 161.994 1.00 24.16 ? 285 VAL A CB  1 
ATOM   1951 C CG1 . VAL A 1 257 ? 173.817 193.002 161.723 1.00 24.16 ? 285 VAL A CG1 1 
ATOM   1952 C CG2 . VAL A 1 257 ? 175.803 192.210 162.972 1.00 24.16 ? 285 VAL A CG2 1 
ATOM   1953 N N   . ASP A 1 258 ? 174.874 193.720 158.645 1.00 26.02 ? 286 ASP A N   1 
ATOM   1954 C CA  . ASP A 1 258 ? 174.318 194.586 157.616 1.00 26.02 ? 286 ASP A CA  1 
ATOM   1955 C C   . ASP A 1 258 ? 172.828 194.317 157.462 1.00 26.02 ? 286 ASP A C   1 
ATOM   1956 O O   . ASP A 1 258 ? 172.283 193.364 158.023 1.00 26.02 ? 286 ASP A O   1 
ATOM   1957 C CB  . ASP A 1 258 ? 175.046 194.408 156.277 1.00 26.02 ? 286 ASP A CB  1 
ATOM   1958 C CG  . ASP A 1 258 ? 174.906 193.010 155.711 1.00 26.02 ? 286 ASP A CG  1 
ATOM   1959 O OD1 . ASP A 1 258 ? 174.280 192.151 156.361 1.00 26.02 ? 286 ASP A OD1 1 
ATOM   1960 O OD2 . ASP A 1 258 ? 175.434 192.766 154.606 1.00 26.02 ? 286 ASP A OD2 1 
ATOM   1961 N N   . PHE A 1 259 ? 172.174 195.165 156.665 1.00 22.92 ? 287 PHE A N   1 
ATOM   1962 C CA  . PHE A 1 259 ? 170.717 195.164 156.583 1.00 22.92 ? 287 PHE A CA  1 
ATOM   1963 C C   . PHE A 1 259 ? 170.143 193.846 156.083 1.00 22.92 ? 287 PHE A C   1 
ATOM   1964 O O   . PHE A 1 259 ? 168.986 193.536 156.384 1.00 22.92 ? 287 PHE A O   1 
ATOM   1965 C CB  . PHE A 1 259 ? 170.248 196.304 155.679 1.00 22.92 ? 287 PHE A CB  1 
ATOM   1966 C CG  . PHE A 1 259 ? 168.768 196.539 155.719 1.00 22.92 ? 287 PHE A CG  1 
ATOM   1967 C CD1 . PHE A 1 259 ? 168.104 196.649 156.923 1.00 22.92 ? 287 PHE A CD1 1 
ATOM   1968 C CD2 . PHE A 1 259 ? 168.043 196.659 154.551 1.00 22.92 ? 287 PHE A CD2 1 
ATOM   1969 C CE1 . PHE A 1 259 ? 166.748 196.870 156.959 1.00 22.92 ? 287 PHE A CE1 1 
ATOM   1970 C CE2 . PHE A 1 259 ? 166.687 196.879 154.585 1.00 22.92 ? 287 PHE A CE2 1 
ATOM   1971 C CZ  . PHE A 1 259 ? 166.041 196.983 155.792 1.00 22.92 ? 287 PHE A CZ  1 
ATOM   1972 N N   . LYS A 1 260 ? 170.913 193.063 155.328 1.00 22.52 ? 288 LYS A N   1 
ATOM   1973 C CA  . LYS A 1 260 ? 170.380 191.808 154.814 1.00 22.52 ? 288 LYS A CA  1 
ATOM   1974 C C   . LYS A 1 260 ? 170.185 190.785 155.923 1.00 22.52 ? 288 LYS A C   1 
ATOM   1975 O O   . LYS A 1 260 ? 169.290 189.938 155.833 1.00 22.52 ? 288 LYS A O   1 
ATOM   1976 C CB  . LYS A 1 260 ? 171.301 191.248 153.731 1.00 22.52 ? 288 LYS A CB  1 
ATOM   1977 N N   . GLU A 1 261 ? 171.015 190.841 156.965 1.00 26.07 ? 289 GLU A N   1 
ATOM   1978 C CA  . GLU A 1 261 ? 170.971 189.883 158.059 1.00 26.07 ? 289 GLU A CA  1 
ATOM   1979 C C   . GLU A 1 261 ? 170.480 190.472 159.375 1.00 26.07 ? 289 GLU A C   1 
ATOM   1980 O O   . GLU A 1 261 ? 170.073 189.711 160.256 1.00 26.07 ? 289 GLU A O   1 
ATOM   1981 C CB  . GLU A 1 261 ? 172.359 189.250 158.236 1.00 26.07 ? 289 GLU A CB  1 
ATOM   1982 C CG  . GLU A 1 261 ? 173.442 190.211 158.673 1.00 26.07 ? 289 GLU A CG  1 
ATOM   1983 C CD  . GLU A 1 261 ? 174.802 189.546 158.751 1.00 26.07 ? 289 GLU A CD  1 
ATOM   1984 O OE1 . GLU A 1 261 ? 174.889 188.342 158.439 1.00 26.07 ? 289 GLU A OE1 1 
ATOM   1985 O OE2 . GLU A 1 261 ? 175.789 190.228 159.096 1.00 26.07 ? 289 GLU A OE2 1 
ATOM   1986 N N   . PHE A 1 262 ? 170.457 191.800 159.505 1.00 18.94 ? 290 PHE A N   1 
ATOM   1987 C CA  . PHE A 1 262 ? 169.818 192.435 160.654 1.00 18.94 ? 290 PHE A CA  1 
ATOM   1988 C C   . PHE A 1 262 ? 168.338 192.079 160.722 1.00 18.94 ? 290 PHE A C   1 
ATOM   1989 O O   . PHE A 1 262 ? 167.834 191.670 161.774 1.00 18.94 ? 290 PHE A O   1 
ATOM   1990 C CB  . PHE A 1 262 ? 170.018 193.950 160.570 1.00 18.94 ? 290 PHE A CB  1 
ATOM   1991 C CG  . PHE A 1 262 ? 169.232 194.741 161.577 1.00 18.94 ? 290 PHE A CG  1 
ATOM   1992 C CD1 . PHE A 1 262 ? 169.181 194.366 162.902 1.00 18.94 ? 290 PHE A CD1 1 
ATOM   1993 C CD2 . PHE A 1 262 ? 168.565 195.889 161.192 1.00 18.94 ? 290 PHE A CD2 1 
ATOM   1994 C CE1 . PHE A 1 262 ? 168.460 195.112 163.818 1.00 18.94 ? 290 PHE A CE1 1 
ATOM   1995 C CE2 . PHE A 1 262 ? 167.849 196.635 162.103 1.00 18.94 ? 290 PHE A CE2 1 
ATOM   1996 C CZ  . PHE A 1 262 ? 167.795 196.247 163.415 1.00 18.94 ? 290 PHE A CZ  1 
ATOM   1997 N N   . ILE A 1 263 ? 167.626 192.210 159.601 1.00 25.44 ? 291 ILE A N   1 
ATOM   1998 C CA  . ILE A 1 263 ? 166.198 191.908 159.602 1.00 25.44 ? 291 ILE A CA  1 
ATOM   1999 C C   . ILE A 1 263 ? 165.961 190.417 159.795 1.00 25.44 ? 291 ILE A C   1 
ATOM   2000 O O   . ILE A 1 263 ? 164.990 190.012 160.442 1.00 25.44 ? 291 ILE A O   1 
ATOM   2001 C CB  . ILE A 1 263 ? 165.526 192.430 158.319 1.00 25.44 ? 291 ILE A CB  1 
ATOM   2002 C CG1 . ILE A 1 263 ? 166.113 191.760 157.080 1.00 25.44 ? 291 ILE A CG1 1 
ATOM   2003 C CG2 . ILE A 1 263 ? 165.666 193.926 158.224 1.00 25.44 ? 291 ILE A CG2 1 
ATOM   2004 C CD1 . ILE A 1 263 ? 165.405 192.136 155.802 1.00 25.44 ? 291 ILE A CD1 1 
ATOM   2005 N N   . GLU A 1 264 ? 166.829 189.574 159.235 1.00 26.10 ? 292 GLU A N   1 
ATOM   2006 C CA  . GLU A 1 264 ? 166.682 188.139 159.443 1.00 26.10 ? 292 GLU A CA  1 
ATOM   2007 C C   . GLU A 1 264 ? 166.881 187.778 160.907 1.00 26.10 ? 292 GLU A C   1 
ATOM   2008 O O   . GLU A 1 264 ? 166.196 186.896 161.435 1.00 26.10 ? 292 GLU A O   1 
ATOM   2009 C CB  . GLU A 1 264 ? 167.662 187.369 158.560 1.00 26.10 ? 292 GLU A CB  1 
ATOM   2010 C CG  . GLU A 1 264 ? 167.362 187.466 157.076 1.00 26.10 ? 292 GLU A CG  1 
ATOM   2011 C CD  . GLU A 1 264 ? 168.370 186.722 156.226 1.00 26.10 ? 292 GLU A CD  1 
ATOM   2012 O OE1 . GLU A 1 264 ? 169.364 186.215 156.785 1.00 26.10 ? 292 GLU A OE1 1 
ATOM   2013 O OE2 . GLU A 1 264 ? 168.172 186.649 154.996 1.00 26.10 ? 292 GLU A OE2 1 
ATOM   2014 N N   . GLY A 1 265 ? 167.824 188.441 161.577 1.00 26.49 ? 293 GLY A N   1 
ATOM   2015 C CA  . GLY A 1 265 ? 168.002 188.209 162.999 1.00 26.49 ? 293 GLY A CA  1 
ATOM   2016 C C   . GLY A 1 265 ? 166.823 188.682 163.828 1.00 26.49 ? 293 GLY A C   1 
ATOM   2017 O O   . GLY A 1 265 ? 166.372 187.979 164.735 1.00 26.49 ? 293 GLY A O   1 
ATOM   2018 N N   . VAL A 1 266 ? 166.307 189.876 163.532 1.00 24.04 ? 294 VAL A N   1 
ATOM   2019 C CA  . VAL A 1 266 ? 165.181 190.396 164.302 1.00 24.04 ? 294 VAL A CA  1 
ATOM   2020 C C   . VAL A 1 266 ? 163.914 189.600 164.008 1.00 24.04 ? 294 VAL A C   1 
ATOM   2021 O O   . VAL A 1 266 ? 163.123 189.312 164.914 1.00 24.04 ? 294 VAL A O   1 
ATOM   2022 C CB  . VAL A 1 266 ? 164.995 191.898 164.027 1.00 24.04 ? 294 VAL A CB  1 
ATOM   2023 C CG1 . VAL A 1 266 ? 163.615 192.351 164.448 1.00 24.04 ? 294 VAL A CG1 1 
ATOM   2024 C CG2 . VAL A 1 266 ? 166.046 192.690 164.765 1.00 24.04 ? 294 VAL A CG2 1 
ATOM   2025 N N   . SER A 1 267 ? 163.707 189.211 162.747 1.00 29.51 ? 295 SER A N   1 
ATOM   2026 C CA  . SER A 1 267 ? 162.519 188.448 162.380 1.00 29.51 ? 295 SER A CA  1 
ATOM   2027 C C   . SER A 1 267 ? 162.485 187.072 163.021 1.00 29.51 ? 295 SER A C   1 
ATOM   2028 O O   . SER A 1 267 ? 161.442 186.413 162.976 1.00 29.51 ? 295 SER A O   1 
ATOM   2029 C CB  . SER A 1 267 ? 162.429 188.287 160.867 1.00 29.51 ? 295 SER A CB  1 
ATOM   2030 O OG  . SER A 1 267 ? 163.268 187.238 160.427 1.00 29.51 ? 295 SER A OG  1 
ATOM   2031 N N   . GLN A 1 268 ? 163.601 186.618 163.592 1.00 34.36 ? 296 GLN A N   1 
ATOM   2032 C CA  . GLN A 1 268 ? 163.601 185.389 164.373 1.00 34.36 ? 296 GLN A CA  1 
ATOM   2033 C C   . GLN A 1 268 ? 162.686 185.496 165.582 1.00 34.36 ? 296 GLN A C   1 
ATOM   2034 O O   . GLN A 1 268 ? 162.277 184.470 166.135 1.00 34.36 ? 296 GLN A O   1 
ATOM   2035 C CB  . GLN A 1 268 ? 165.027 185.067 164.816 1.00 34.36 ? 296 GLN A CB  1 
ATOM   2036 C CG  . GLN A 1 268 ? 165.321 183.600 165.011 1.00 34.36 ? 296 GLN A CG  1 
ATOM   2037 C CD  . GLN A 1 268 ? 166.804 183.312 164.953 1.00 34.36 ? 296 GLN A CD  1 
ATOM   2038 O OE1 . GLN A 1 268 ? 167.616 184.223 164.794 1.00 34.36 ? 296 GLN A OE1 1 
ATOM   2039 N NE2 . GLN A 1 268 ? 167.169 182.042 165.082 1.00 34.36 ? 296 GLN A NE2 1 
ATOM   2040 N N   . PHE A 1 269 ? 162.362 186.716 165.999 1.00 34.30 ? 297 PHE A N   1 
ATOM   2041 C CA  . PHE A 1 269 ? 161.490 186.980 167.134 1.00 34.30 ? 297 PHE A CA  1 
ATOM   2042 C C   . PHE A 1 269 ? 160.246 187.687 166.619 1.00 34.30 ? 297 PHE A C   1 
ATOM   2043 O O   . PHE A 1 269 ? 160.352 188.718 165.949 1.00 34.30 ? 297 PHE A O   1 
ATOM   2044 C CB  . PHE A 1 269 ? 162.207 187.847 168.163 1.00 34.30 ? 297 PHE A CB  1 
ATOM   2045 C CG  . PHE A 1 269 ? 163.342 187.158 168.842 1.00 34.30 ? 297 PHE A CG  1 
ATOM   2046 C CD1 . PHE A 1 269 ? 163.485 185.787 168.765 1.00 34.30 ? 297 PHE A CD1 1 
ATOM   2047 C CD2 . PHE A 1 269 ? 164.282 187.882 169.536 1.00 34.30 ? 297 PHE A CD2 1 
ATOM   2048 C CE1 . PHE A 1 269 ? 164.536 185.156 169.385 1.00 34.30 ? 297 PHE A CE1 1 
ATOM   2049 C CE2 . PHE A 1 269 ? 165.334 187.259 170.153 1.00 34.30 ? 297 PHE A CE2 1 
ATOM   2050 C CZ  . PHE A 1 269 ? 165.462 185.896 170.079 1.00 34.30 ? 297 PHE A CZ  1 
ATOM   2051 N N   . SER A 1 270 ? 159.076 187.141 166.927 1.00 42.16 ? 298 SER A N   1 
ATOM   2052 C CA  . SER A 1 270 ? 157.834 187.747 166.471 1.00 42.16 ? 298 SER A CA  1 
ATOM   2053 C C   . SER A 1 270 ? 156.710 187.334 167.404 1.00 42.16 ? 298 SER A C   1 
ATOM   2054 O O   . SER A 1 270 ? 156.844 186.396 168.193 1.00 42.16 ? 298 SER A O   1 
ATOM   2055 C CB  . SER A 1 270 ? 157.501 187.351 165.030 1.00 42.16 ? 298 SER A CB  1 
ATOM   2056 O OG  . SER A 1 270 ? 158.549 187.700 164.147 1.00 42.16 ? 298 SER A OG  1 
ATOM   2057 N N   . VAL A 1 271 ? 155.596 188.059 167.302 1.00 45.27 ? 299 VAL A N   1 
ATOM   2058 C CA  . VAL A 1 271 ? 154.420 187.722 168.094 1.00 45.27 ? 299 VAL A CA  1 
ATOM   2059 C C   . VAL A 1 271 ? 153.856 186.372 167.667 1.00 45.27 ? 299 VAL A C   1 
ATOM   2060 O O   . VAL A 1 271 ? 153.344 185.609 168.495 1.00 45.27 ? 299 VAL A O   1 
ATOM   2061 C CB  . VAL A 1 271 ? 153.372 188.845 167.992 1.00 45.27 ? 299 VAL A CB  1 
ATOM   2062 C CG1 . VAL A 1 271 ? 153.882 190.097 168.678 1.00 45.27 ? 299 VAL A CG1 1 
ATOM   2063 C CG2 . VAL A 1 271 ? 153.057 189.146 166.538 1.00 45.27 ? 299 VAL A CG2 1 
ATOM   2064 N N   . LYS A 1 272 ? 153.941 186.052 166.376 1.00 49.60 ? 300 LYS A N   1 
ATOM   2065 C CA  . LYS A 1 272 ? 153.422 184.799 165.844 1.00 49.60 ? 300 LYS A CA  1 
ATOM   2066 C C   . LYS A 1 272 ? 154.520 183.876 165.330 1.00 49.60 ? 300 LYS A C   1 
ATOM   2067 O O   . LYS A 1 272 ? 154.226 182.944 164.575 1.00 49.60 ? 300 LYS A O   1 
ATOM   2068 C CB  . LYS A 1 272 ? 152.409 185.079 164.731 1.00 49.60 ? 300 LYS A CB  1 
ATOM   2069 N N   . GLY A 1 273 ? 155.772 184.109 165.717 1.00 46.71 ? 301 GLY A N   1 
ATOM   2070 C CA  . GLY A 1 273 ? 156.851 183.261 165.259 1.00 46.71 ? 301 GLY A CA  1 
ATOM   2071 C C   . GLY A 1 273 ? 156.779 181.865 165.846 1.00 46.71 ? 301 GLY A C   1 
ATOM   2072 O O   . GLY A 1 273 ? 156.117 181.609 166.852 1.00 46.71 ? 301 GLY A O   1 
ATOM   2073 N N   . ASP A 1 274 ? 157.476 180.941 165.191 1.00 52.89 ? 302 ASP A N   1 
ATOM   2074 C CA  . ASP A 1 274 ? 157.455 179.548 165.612 1.00 52.89 ? 302 ASP A CA  1 
ATOM   2075 C C   . ASP A 1 274 ? 158.123 179.377 166.971 1.00 52.89 ? 302 ASP A C   1 
ATOM   2076 O O   . ASP A 1 274 ? 159.069 180.086 167.321 1.00 52.89 ? 302 ASP A O   1 
ATOM   2077 C CB  . ASP A 1 274 ? 158.156 178.663 164.584 1.00 52.89 ? 302 ASP A CB  1 
ATOM   2078 C CG  . ASP A 1 274 ? 157.472 178.682 163.236 1.00 52.89 ? 302 ASP A CG  1 
ATOM   2079 O OD1 . ASP A 1 274 ? 157.809 177.830 162.388 1.00 52.89 ? 302 ASP A OD1 1 
ATOM   2080 O OD2 . ASP A 1 274 ? 156.602 179.550 163.023 1.00 52.89 ? 302 ASP A OD2 1 
ATOM   2081 N N   . LYS A 1 275 ? 157.608 178.421 167.744 1.00 53.83 ? 303 LYS A N   1 
ATOM   2082 C CA  . LYS A 1 275 ? 158.221 178.079 169.023 1.00 53.83 ? 303 LYS A CA  1 
ATOM   2083 C C   . LYS A 1 275 ? 159.613 177.490 168.823 1.00 53.83 ? 303 LYS A C   1 
ATOM   2084 O O   . LYS A 1 275 ? 160.537 177.777 169.598 1.00 53.83 ? 303 LYS A O   1 
ATOM   2085 C CB  . LYS A 1 275 ? 157.282 177.136 169.787 1.00 53.83 ? 303 LYS A CB  1 
ATOM   2086 C CG  . LYS A 1 275 ? 157.830 176.340 170.978 1.00 53.83 ? 303 LYS A CG  1 
ATOM   2087 C CD  . LYS A 1 275 ? 158.647 175.112 170.583 1.00 53.83 ? 303 LYS A CD  1 
ATOM   2088 C CE  . LYS A 1 275 ? 159.334 174.497 171.787 1.00 53.83 ? 303 LYS A CE  1 
ATOM   2089 N NZ  . LYS A 1 275 ? 159.991 173.207 171.442 1.00 53.83 ? 303 LYS A NZ  1 
ATOM   2090 N N   . GLU A 1 276 ? 159.781 176.667 167.786 1.00 50.05 ? 304 GLU A N   1 
ATOM   2091 C CA  . GLU A 1 276 ? 161.073 176.037 167.541 1.00 50.05 ? 304 GLU A CA  1 
ATOM   2092 C C   . GLU A 1 276 ? 162.150 177.069 167.233 1.00 50.05 ? 304 GLU A C   1 
ATOM   2093 O O   . GLU A 1 276 ? 163.302 176.908 167.644 1.00 50.05 ? 304 GLU A O   1 
ATOM   2094 C CB  . GLU A 1 276 ? 160.961 175.028 166.400 1.00 50.05 ? 304 GLU A CB  1 
ATOM   2095 C CG  . GLU A 1 276 ? 162.132 174.060 166.310 1.00 50.05 ? 304 GLU A CG  1 
ATOM   2096 C CD  . GLU A 1 276 ? 162.205 173.092 167.478 1.00 50.05 ? 304 GLU A CD  1 
ATOM   2097 O OE1 . GLU A 1 276 ? 161.276 173.075 168.311 1.00 50.05 ? 304 GLU A OE1 1 
ATOM   2098 O OE2 . GLU A 1 276 ? 163.200 172.345 167.563 1.00 50.05 ? 304 GLU A OE2 1 
ATOM   2099 N N   . GLN A 1 277 ? 161.799 178.131 166.504 1.00 50.11 ? 305 GLN A N   1 
ATOM   2100 C CA  . GLN A 1 277 ? 162.779 179.166 166.190 1.00 50.11 ? 305 GLN A CA  1 
ATOM   2101 C C   . GLN A 1 277 ? 163.299 179.832 167.458 1.00 50.11 ? 305 GLN A C   1 
ATOM   2102 O O   . GLN A 1 277 ? 164.509 180.036 167.620 1.00 50.11 ? 305 GLN A O   1 
ATOM   2103 C CB  . GLN A 1 277 ? 162.161 180.203 165.254 1.00 50.11 ? 305 GLN A CB  1 
ATOM   2104 C CG  . GLN A 1 277 ? 161.848 179.679 163.867 1.00 50.11 ? 305 GLN A CG  1 
ATOM   2105 C CD  . GLN A 1 277 ? 163.047 179.035 163.200 1.00 50.11 ? 305 GLN A CD  1 
ATOM   2106 O OE1 . GLN A 1 277 ? 162.980 177.894 162.746 1.00 50.11 ? 305 GLN A OE1 1 
ATOM   2107 N NE2 . GLN A 1 277 ? 164.151 179.769 163.131 1.00 50.11 ? 305 GLN A NE2 1 
ATOM   2108 N N   . LYS A 1 278 ? 162.395 180.167 168.379 1.00 44.18 ? 306 LYS A N   1 
ATOM   2109 C CA  . LYS A 1 278 ? 162.812 180.826 169.611 1.00 44.18 ? 306 LYS A CA  1 
ATOM   2110 C C   . LYS A 1 278 ? 163.606 179.883 170.505 1.00 44.18 ? 306 LYS A C   1 
ATOM   2111 O O   . LYS A 1 278 ? 164.589 180.297 171.131 1.00 44.18 ? 306 LYS A O   1 
ATOM   2112 C CB  . LYS A 1 278 ? 161.592 181.380 170.340 1.00 44.18 ? 306 LYS A CB  1 
ATOM   2113 C CG  . LYS A 1 278 ? 160.867 182.454 169.549 1.00 44.18 ? 306 LYS A CG  1 
ATOM   2114 C CD  . LYS A 1 278 ? 159.577 182.867 170.219 1.00 44.18 ? 306 LYS A CD  1 
ATOM   2115 C CE  . LYS A 1 278 ? 158.833 183.892 169.391 1.00 44.18 ? 306 LYS A CE  1 
ATOM   2116 N NZ  . LYS A 1 278 ? 157.555 184.286 170.039 1.00 44.18 ? 306 LYS A NZ  1 
ATOM   2117 N N   . LEU A 1 279 ? 163.211 178.609 170.572 1.00 43.80 ? 307 LEU A N   1 
ATOM   2118 C CA  . LEU A 1 279 ? 163.995 177.659 171.357 1.00 43.80 ? 307 LEU A CA  1 
ATOM   2119 C C   . LEU A 1 279 ? 165.387 177.467 170.765 1.00 43.80 ? 307 LEU A C   1 
ATOM   2120 O O   . LEU A 1 279 ? 166.376 177.362 171.501 1.00 43.80 ? 307 LEU A O   1 
ATOM   2121 C CB  . LEU A 1 279 ? 163.267 176.323 171.459 1.00 43.80 ? 307 LEU A CB  1 
ATOM   2122 C CG  . LEU A 1 279 ? 163.617 175.535 172.719 1.00 43.80 ? 307 LEU A CG  1 
ATOM   2123 C CD1 . LEU A 1 279 ? 163.465 176.412 173.947 1.00 43.80 ? 307 LEU A CD1 1 
ATOM   2124 C CD2 . LEU A 1 279 ? 162.756 174.300 172.839 1.00 43.80 ? 307 LEU A CD2 1 
ATOM   2125 N N   . ARG A 1 280 ? 165.486 177.422 169.436 1.00 43.41 ? 308 ARG A N   1 
ATOM   2126 C CA  . ARG A 1 280 ? 166.789 177.318 168.791 1.00 43.41 ? 308 ARG A CA  1 
ATOM   2127 C C   . ARG A 1 280 ? 167.646 178.542 169.087 1.00 43.41 ? 308 ARG A C   1 
ATOM   2128 O O   . ARG A 1 280 ? 168.853 178.421 169.328 1.00 43.41 ? 308 ARG A O   1 
ATOM   2129 C CB  . ARG A 1 280 ? 166.608 177.135 167.285 1.00 43.41 ? 308 ARG A CB  1 
ATOM   2130 C CG  . ARG A 1 280 ? 167.905 177.057 166.507 1.00 43.41 ? 308 ARG A CG  1 
ATOM   2131 C CD  . ARG A 1 280 ? 168.583 175.717 166.714 1.00 43.41 ? 308 ARG A CD  1 
ATOM   2132 N NE  . ARG A 1 280 ? 170.010 175.771 166.417 1.00 43.41 ? 308 ARG A NE  1 
ATOM   2133 C CZ  . ARG A 1 280 ? 170.779 174.700 166.262 1.00 43.41 ? 308 ARG A CZ  1 
ATOM   2134 N NH1 . ARG A 1 280 ? 170.259 173.486 166.378 1.00 43.41 ? 308 ARG A NH1 1 
ATOM   2135 N NH2 . ARG A 1 280 ? 172.069 174.841 165.996 1.00 43.41 ? 308 ARG A NH2 1 
ATOM   2136 N N   . PHE A 1 281 ? 167.041 179.732 169.071 1.00 35.61 ? 309 PHE A N   1 
ATOM   2137 C CA  . PHE A 1 281 ? 167.793 180.932 169.422 1.00 35.61 ? 309 PHE A CA  1 
ATOM   2138 C C   . PHE A 1 281 ? 168.288 180.865 170.858 1.00 35.61 ? 309 PHE A C   1 
ATOM   2139 O O   . PHE A 1 281 ? 169.421 181.262 171.150 1.00 35.61 ? 309 PHE A O   1 
ATOM   2140 C CB  . PHE A 1 281 ? 166.939 182.180 169.217 1.00 35.61 ? 309 PHE A CB  1 
ATOM   2141 C CG  . PHE A 1 281 ? 167.725 183.462 169.240 1.00 35.61 ? 309 PHE A CG  1 
ATOM   2142 C CD1 . PHE A 1 281 ? 168.012 184.131 168.065 1.00 35.61 ? 309 PHE A CD1 1 
ATOM   2143 C CD2 . PHE A 1 281 ? 168.176 183.997 170.431 1.00 35.61 ? 309 PHE A CD2 1 
ATOM   2144 C CE1 . PHE A 1 281 ? 168.730 185.309 168.079 1.00 35.61 ? 309 PHE A CE1 1 
ATOM   2145 C CE2 . PHE A 1 281 ? 168.894 185.170 170.448 1.00 35.61 ? 309 PHE A CE2 1 
ATOM   2146 C CZ  . PHE A 1 281 ? 169.170 185.828 169.271 1.00 35.61 ? 309 PHE A CZ  1 
ATOM   2147 N N   . ALA A 1 282 ? 167.447 180.378 171.773 1.00 34.40 ? 310 ALA A N   1 
ATOM   2148 C CA  . ALA A 1 282 ? 167.878 180.227 173.159 1.00 34.40 ? 310 ALA A CA  1 
ATOM   2149 C C   . ALA A 1 282 ? 169.044 179.254 173.265 1.00 34.40 ? 310 ALA A C   1 
ATOM   2150 O O   . ALA A 1 282 ? 169.970 179.463 174.056 1.00 34.40 ? 310 ALA A O   1 
ATOM   2151 C CB  . ALA A 1 282 ? 166.711 179.762 174.027 1.00 34.40 ? 310 ALA A CB  1 
ATOM   2152 N N   . PHE A 1 283 ? 169.010 178.181 172.475 1.00 34.90 ? 311 PHE A N   1 
ATOM   2153 C CA  . PHE A 1 283 ? 170.117 177.229 172.462 1.00 34.90 ? 311 PHE A CA  1 
ATOM   2154 C C   . PHE A 1 283 ? 171.398 177.871 171.950 1.00 34.90 ? 311 PHE A C   1 
ATOM   2155 O O   . PHE A 1 283 ? 172.483 177.616 172.481 1.00 34.90 ? 311 PHE A O   1 
ATOM   2156 C CB  . PHE A 1 283 ? 169.751 176.020 171.604 1.00 34.90 ? 311 PHE A CB  1 
ATOM   2157 C CG  . PHE A 1 283 ? 170.803 174.950 171.572 1.00 34.90 ? 311 PHE A CG  1 
ATOM   2158 C CD1 . PHE A 1 283 ? 170.773 173.908 172.476 1.00 34.90 ? 311 PHE A CD1 1 
ATOM   2159 C CD2 . PHE A 1 283 ? 171.803 174.970 170.623 1.00 34.90 ? 311 PHE A CD2 1 
ATOM   2160 C CE1 . PHE A 1 283 ? 171.731 172.919 172.444 1.00 34.90 ? 311 PHE A CE1 1 
ATOM   2161 C CE2 . PHE A 1 283 ? 172.761 173.983 170.590 1.00 34.90 ? 311 PHE A CE2 1 
ATOM   2162 C CZ  . PHE A 1 283 ? 172.724 172.957 171.501 1.00 34.90 ? 311 PHE A CZ  1 
ATOM   2163 N N   . ARG A 1 284 ? 171.293 178.707 170.918 1.00 30.62 ? 312 ARG A N   1 
ATOM   2164 C CA  . ARG A 1 284 ? 172.484 179.233 170.259 1.00 30.62 ? 312 ARG A CA  1 
ATOM   2165 C C   . ARG A 1 284 ? 173.276 180.209 171.121 1.00 30.62 ? 312 ARG A C   1 
ATOM   2166 O O   . ARG A 1 284 ? 174.383 180.587 170.726 1.00 30.62 ? 312 ARG A O   1 
ATOM   2167 C CB  . ARG A 1 284 ? 172.102 179.901 168.938 1.00 30.62 ? 312 ARG A CB  1 
ATOM   2168 C CG  . ARG A 1 284 ? 171.600 178.924 167.886 1.00 30.62 ? 312 ARG A CG  1 
ATOM   2169 C CD  . ARG A 1 284 ? 172.326 179.094 166.564 1.00 30.62 ? 312 ARG A CD  1 
ATOM   2170 N NE  . ARG A 1 284 ? 171.957 180.339 165.900 1.00 30.62 ? 312 ARG A NE  1 
ATOM   2171 C CZ  . ARG A 1 284 ? 170.892 180.479 165.120 1.00 30.62 ? 312 ARG A CZ  1 
ATOM   2172 N NH1 . ARG A 1 284 ? 170.088 179.450 164.902 1.00 30.62 ? 312 ARG A NH1 1 
ATOM   2173 N NH2 . ARG A 1 284 ? 170.631 181.649 164.556 1.00 30.62 ? 312 ARG A NH2 1 
ATOM   2174 N N   . ILE A 1 285 ? 172.744 180.636 172.268 1.00 22.63 ? 313 ILE A N   1 
ATOM   2175 C CA  . ILE A 1 285 ? 173.523 181.488 173.161 1.00 22.63 ? 313 ILE A CA  1 
ATOM   2176 C C   . ILE A 1 285 ? 174.705 180.721 173.738 1.00 22.63 ? 313 ILE A C   1 
ATOM   2177 O O   . ILE A 1 285 ? 175.785 181.288 173.938 1.00 22.63 ? 313 ILE A O   1 
ATOM   2178 C CB  . ILE A 1 285 ? 172.634 182.063 174.279 1.00 22.63 ? 313 ILE A CB  1 
ATOM   2179 C CG1 . ILE A 1 285 ? 171.493 182.891 173.693 1.00 22.63 ? 313 ILE A CG1 1 
ATOM   2180 C CG2 . ILE A 1 285 ? 173.450 182.921 175.223 1.00 22.63 ? 313 ILE A CG2 1 
ATOM   2181 C CD1 . ILE A 1 285 ? 171.877 184.307 173.349 1.00 22.63 ? 313 ILE A CD1 1 
ATOM   2182 N N   . TYR A 1 286 ? 174.529 179.425 174.008 1.00 24.21 ? 314 TYR A N   1 
ATOM   2183 C CA  . TYR A 1 286 ? 175.560 178.630 174.663 1.00 24.21 ? 314 TYR A CA  1 
ATOM   2184 C C   . TYR A 1 286 ? 176.614 178.095 173.701 1.00 24.21 ? 314 TYR A C   1 
ATOM   2185 O O   . TYR A 1 286 ? 177.724 177.781 174.141 1.00 24.21 ? 314 TYR A O   1 
ATOM   2186 C CB  . TYR A 1 286 ? 174.912 177.473 175.423 1.00 24.21 ? 314 TYR A CB  1 
ATOM   2187 C CG  . TYR A 1 286 ? 173.968 177.934 176.512 1.00 24.21 ? 314 TYR A CG  1 
ATOM   2188 C CD1 . TYR A 1 286 ? 174.433 178.664 177.594 1.00 24.21 ? 314 TYR A CD1 1 
ATOM   2189 C CD2 . TYR A 1 286 ? 172.613 177.650 176.451 1.00 24.21 ? 314 TYR A CD2 1 
ATOM   2190 C CE1 . TYR A 1 286 ? 173.579 179.091 178.585 1.00 24.21 ? 314 TYR A CE1 1 
ATOM   2191 C CE2 . TYR A 1 286 ? 171.753 178.074 177.438 1.00 24.21 ? 314 TYR A CE2 1 
ATOM   2192 C CZ  . TYR A 1 286 ? 172.242 178.794 178.500 1.00 24.21 ? 314 TYR A CZ  1 
ATOM   2193 O OH  . TYR A 1 286 ? 171.390 179.220 179.485 1.00 24.21 ? 314 TYR A OH  1 
ATOM   2194 N N   . ASP A 1 287 ? 176.304 177.983 172.410 1.00 30.63 ? 315 ASP A N   1 
ATOM   2195 C CA  . ASP A 1 287 ? 177.286 177.547 171.423 1.00 30.63 ? 315 ASP A CA  1 
ATOM   2196 C C   . ASP A 1 287 ? 178.283 178.654 171.116 1.00 30.63 ? 315 ASP A C   1 
ATOM   2197 O O   . ASP A 1 287 ? 178.079 179.431 170.178 1.00 30.63 ? 315 ASP A O   1 
ATOM   2198 C CB  . ASP A 1 287 ? 176.602 177.118 170.127 1.00 30.63 ? 315 ASP A CB  1 
ATOM   2199 C CG  . ASP A 1 287 ? 176.202 175.670 170.133 1.00 30.63 ? 315 ASP A CG  1 
ATOM   2200 O OD1 . ASP A 1 287 ? 176.861 174.876 170.833 1.00 30.63 ? 315 ASP A OD1 1 
ATOM   2201 O OD2 . ASP A 1 287 ? 175.239 175.320 169.423 1.00 30.63 ? 315 ASP A OD2 1 
ATOM   2202 N N   . MET A 1 288 ? 179.370 178.731 171.879 1.00 24.56 ? 316 MET A N   1 
ATOM   2203 C CA  . MET A 1 288 ? 180.324 179.815 171.689 1.00 24.56 ? 316 MET A CA  1 
ATOM   2204 C C   . MET A 1 288 ? 181.138 179.682 170.409 1.00 24.56 ? 316 MET A C   1 
ATOM   2205 O O   . MET A 1 288 ? 181.842 180.630 170.045 1.00 24.56 ? 316 MET A O   1 
ATOM   2206 C CB  . MET A 1 288 ? 181.265 179.911 172.890 1.00 24.56 ? 316 MET A CB  1 
ATOM   2207 C CG  . MET A 1 288 ? 180.658 180.616 174.086 1.00 24.56 ? 316 MET A CG  1 
ATOM   2208 S SD  . MET A 1 288 ? 181.901 181.114 175.284 1.00 24.56 ? 316 MET A SD  1 
ATOM   2209 C CE  . MET A 1 288 ? 183.236 181.603 174.202 1.00 24.56 ? 316 MET A CE  1 
ATOM   2210 N N   . ASP A 1 289 ? 181.063 178.545 169.716 1.00 34.34 ? 317 ASP A N   1 
ATOM   2211 C CA  . ASP A 1 289 ? 181.780 178.361 168.462 1.00 34.34 ? 317 ASP A CA  1 
ATOM   2212 C C   . ASP A 1 289 ? 180.871 177.891 167.333 1.00 34.34 ? 317 ASP A C   1 
ATOM   2213 O O   . ASP A 1 289 ? 181.366 177.609 166.236 1.00 34.34 ? 317 ASP A O   1 
ATOM   2214 C CB  . ASP A 1 289 ? 182.935 177.369 168.640 1.00 34.34 ? 317 ASP A CB  1 
ATOM   2215 C CG  . ASP A 1 289 ? 184.075 177.941 169.459 1.00 34.34 ? 317 ASP A CG  1 
ATOM   2216 O OD1 . ASP A 1 289 ? 184.901 177.153 169.964 1.00 34.34 ? 317 ASP A OD1 1 
ATOM   2217 O OD2 . ASP A 1 289 ? 184.150 179.178 169.596 1.00 34.34 ? 317 ASP A OD2 1 
ATOM   2218 N N   . LYS A 1 290 ? 179.562 177.798 167.572 1.00 30.93 ? 318 LYS A N   1 
ATOM   2219 C CA  . LYS A 1 290 ? 178.598 177.307 166.585 1.00 30.93 ? 318 LYS A CA  1 
ATOM   2220 C C   . LYS A 1 290 ? 178.960 175.911 166.093 1.00 30.93 ? 318 LYS A C   1 
ATOM   2221 O O   . LYS A 1 290 ? 178.620 175.526 164.973 1.00 30.93 ? 318 LYS A O   1 
ATOM   2222 C CB  . LYS A 1 290 ? 178.456 178.275 165.407 1.00 30.93 ? 318 LYS A CB  1 
ATOM   2223 C CG  . LYS A 1 290 ? 178.003 179.673 165.809 1.00 30.93 ? 318 LYS A CG  1 
ATOM   2224 C CD  . LYS A 1 290 ? 177.327 180.397 164.659 1.00 30.93 ? 318 LYS A CD  1 
ATOM   2225 C CE  . LYS A 1 290 ? 177.360 181.901 164.859 1.00 30.93 ? 318 LYS A CE  1 
ATOM   2226 N NZ  . LYS A 1 290 ? 178.750 182.429 164.900 1.00 30.93 ? 318 LYS A NZ  1 
ATOM   2227 N N   . ASP A 1 291 ? 179.650 175.143 166.937 1.00 35.02 ? 319 ASP A N   1 
ATOM   2228 C CA  . ASP A 1 291 ? 180.046 173.789 166.577 1.00 35.02 ? 319 ASP A CA  1 
ATOM   2229 C C   . ASP A 1 291 ? 178.876 172.816 166.594 1.00 35.02 ? 319 ASP A C   1 
ATOM   2230 O O   . ASP A 1 291 ? 178.986 171.724 166.028 1.00 35.02 ? 319 ASP A O   1 
ATOM   2231 C CB  . ASP A 1 291 ? 181.150 173.307 167.519 1.00 35.02 ? 319 ASP A CB  1 
ATOM   2232 C CG  . ASP A 1 291 ? 180.865 173.640 168.974 1.00 35.02 ? 319 ASP A CG  1 
ATOM   2233 O OD1 . ASP A 1 291 ? 179.684 173.840 169.325 1.00 35.02 ? 319 ASP A OD1 1 
ATOM   2234 O OD2 . ASP A 1 291 ? 181.825 173.711 169.769 1.00 35.02 ? 319 ASP A OD2 1 
ATOM   2235 N N   . GLY A 1 292 ? 177.763 173.183 167.223 1.00 34.53 ? 320 GLY A N   1 
ATOM   2236 C CA  . GLY A 1 292 ? 176.604 172.325 167.317 1.00 34.53 ? 320 GLY A CA  1 
ATOM   2237 C C   . GLY A 1 292 ? 176.422 171.641 168.655 1.00 34.53 ? 320 GLY A C   1 
ATOM   2238 O O   . GLY A 1 292 ? 175.359 171.055 168.889 1.00 34.53 ? 320 GLY A O   1 
ATOM   2239 N N   . TYR A 1 293 ? 177.419 171.700 169.536 1.00 36.57 ? 321 TYR A N   1 
ATOM   2240 C CA  . TYR A 1 293 ? 177.359 171.037 170.829 1.00 36.57 ? 321 TYR A CA  1 
ATOM   2241 C C   . TYR A 1 293 ? 177.848 171.977 171.921 1.00 36.57 ? 321 TYR A C   1 
ATOM   2242 O O   . TYR A 1 293 ? 178.740 172.800 171.702 1.00 36.57 ? 321 TYR A O   1 
ATOM   2243 C CB  . TYR A 1 293 ? 178.199 169.756 170.839 1.00 36.57 ? 321 TYR A CB  1 
ATOM   2244 C CG  . TYR A 1 293 ? 177.669 168.664 169.940 1.00 36.57 ? 321 TYR A CG  1 
ATOM   2245 C CD1 . TYR A 1 293 ? 176.325 168.328 169.943 1.00 36.57 ? 321 TYR A CD1 1 
ATOM   2246 C CD2 . TYR A 1 293 ? 178.515 167.973 169.084 1.00 36.57 ? 321 TYR A CD2 1 
ATOM   2247 C CE1 . TYR A 1 293 ? 175.839 167.335 169.123 1.00 36.57 ? 321 TYR A CE1 1 
ATOM   2248 C CE2 . TYR A 1 293 ? 178.035 166.979 168.260 1.00 36.57 ? 321 TYR A CE2 1 
ATOM   2249 C CZ  . TYR A 1 293 ? 176.696 166.664 168.284 1.00 36.57 ? 321 TYR A CZ  1 
ATOM   2250 O OH  . TYR A 1 293 ? 176.208 165.674 167.466 1.00 36.57 ? 321 TYR A OH  1 
ATOM   2251 N N   . ILE A 1 294 ? 177.261 171.832 173.106 1.00 29.55 ? 322 ILE A N   1 
ATOM   2252 C CA  . ILE A 1 294 ? 177.593 172.667 174.254 1.00 29.55 ? 322 ILE A CA  1 
ATOM   2253 C C   . ILE A 1 294 ? 178.667 171.955 175.067 1.00 29.55 ? 322 ILE A C   1 
ATOM   2254 O O   . ILE A 1 294 ? 178.398 170.942 175.715 1.00 29.55 ? 322 ILE A O   1 
ATOM   2255 C CB  . ILE A 1 294 ? 176.359 172.960 175.115 1.00 29.55 ? 322 ILE A CB  1 
ATOM   2256 C CG1 . ILE A 1 294 ? 175.194 173.438 174.253 1.00 29.55 ? 322 ILE A CG1 1 
ATOM   2257 C CG2 . ILE A 1 294 ? 176.685 174.000 176.159 1.00 29.55 ? 322 ILE A CG2 1 
ATOM   2258 C CD1 . ILE A 1 294 ? 174.002 173.881 175.058 1.00 29.55 ? 322 ILE A CD1 1 
ATOM   2259 N N   . SER A 1 295 ? 179.882 172.490 175.043 1.00 20.40 ? 323 SER A N   1 
ATOM   2260 C CA  . SER A 1 295 ? 180.974 171.931 175.819 1.00 20.40 ? 323 SER A CA  1 
ATOM   2261 C C   . SER A 1 295 ? 180.852 172.367 177.274 1.00 20.40 ? 323 SER A C   1 
ATOM   2262 O O   . SER A 1 295 ? 179.939 173.099 177.657 1.00 20.40 ? 323 SER A O   1 
ATOM   2263 C CB  . SER A 1 295 ? 182.319 172.355 175.235 1.00 20.40 ? 323 SER A CB  1 
ATOM   2264 O OG  . SER A 1 295 ? 183.391 171.868 176.021 1.00 20.40 ? 323 SER A OG  1 
ATOM   2265 N N   . ASN A 1 296 ? 181.779 171.895 178.105 1.00 17.18 ? 324 ASN A N   1 
ATOM   2266 C CA  . ASN A 1 296 ? 181.838 172.359 179.486 1.00 17.18 ? 324 ASN A CA  1 
ATOM   2267 C C   . ASN A 1 296 ? 182.459 173.747 179.573 1.00 17.18 ? 324 ASN A C   1 
ATOM   2268 O O   . ASN A 1 296 ? 182.001 174.588 180.355 1.00 17.18 ? 324 ASN A O   1 
ATOM   2269 C CB  . ASN A 1 296 ? 182.618 171.358 180.334 1.00 17.18 ? 324 ASN A CB  1 
ATOM   2270 C CG  . ASN A 1 296 ? 182.595 171.692 181.805 1.00 17.18 ? 324 ASN A CG  1 
ATOM   2271 O OD1 . ASN A 1 296 ? 181.900 172.603 182.239 1.00 17.18 ? 324 ASN A OD1 1 
ATOM   2272 N ND2 . ASN A 1 296 ? 183.360 170.946 182.586 1.00 17.18 ? 324 ASN A ND2 1 
ATOM   2273 N N   . GLY A 1 297 ? 183.491 174.010 178.771 1.00 14.75 ? 325 GLY A N   1 
ATOM   2274 C CA  . GLY A 1 297 ? 184.071 175.340 178.743 1.00 14.75 ? 325 GLY A CA  1 
ATOM   2275 C C   . GLY A 1 297 ? 183.101 176.395 178.259 1.00 14.75 ? 325 GLY A C   1 
ATOM   2276 O O   . GLY A 1 297 ? 183.072 177.506 178.789 1.00 14.75 ? 325 GLY A O   1 
ATOM   2277 N N   . GLU A 1 298 ? 182.287 176.063 177.259 1.00 20.97 ? 326 GLU A N   1 
ATOM   2278 C CA  . GLU A 1 298 ? 181.275 177.000 176.792 1.00 20.97 ? 326 GLU A CA  1 
ATOM   2279 C C   . GLU A 1 298 ? 180.211 177.240 177.857 1.00 20.97 ? 326 GLU A C   1 
ATOM   2280 O O   . GLU A 1 298 ? 179.878 178.391 178.160 1.00 20.97 ? 326 GLU A O   1 
ATOM   2281 C CB  . GLU A 1 298 ? 180.647 176.481 175.498 1.00 20.97 ? 326 GLU A CB  1 
ATOM   2282 C CG  . GLU A 1 298 ? 181.641 176.342 174.345 1.00 20.97 ? 326 GLU A CG  1 
ATOM   2283 C CD  . GLU A 1 298 ? 181.211 175.323 173.302 1.00 20.97 ? 326 GLU A CD  1 
ATOM   2284 O OE1 . GLU A 1 298 ? 180.269 174.550 173.568 1.00 20.97 ? 326 GLU A OE1 1 
ATOM   2285 O OE2 . GLU A 1 298 ? 181.822 175.291 172.216 1.00 20.97 ? 326 GLU A OE2 1 
ATOM   2286 N N   . LEU A 1 299 ? 179.675 176.173 178.447 1.00 9.55  ? 327 LEU A N   1 
ATOM   2287 C CA  . LEU A 1 299 ? 178.633 176.315 179.454 1.00 9.55  ? 327 LEU A CA  1 
ATOM   2288 C C   . LEU A 1 299 ? 179.132 176.956 180.741 1.00 9.55  ? 327 LEU A C   1 
ATOM   2289 O O   . LEU A 1 299 ? 178.312 177.423 181.534 1.00 9.55  ? 327 LEU A O   1 
ATOM   2290 C CB  . LEU A 1 299 ? 178.012 174.952 179.763 1.00 9.55  ? 327 LEU A CB  1 
ATOM   2291 C CG  . LEU A 1 299 ? 176.727 174.901 180.591 1.00 9.55  ? 327 LEU A CG  1 
ATOM   2292 C CD1 . LEU A 1 299 ? 175.762 175.972 180.148 1.00 9.55  ? 327 LEU A CD1 1 
ATOM   2293 C CD2 . LEU A 1 299 ? 176.084 173.537 180.479 1.00 9.55  ? 327 LEU A CD2 1 
ATOM   2294 N N   . PHE A 1 300 ? 180.440 176.996 180.975 1.00 7.52  ? 328 PHE A N   1 
ATOM   2295 C CA  . PHE A 1 300 ? 180.972 177.724 182.119 1.00 7.52  ? 328 PHE A CA  1 
ATOM   2296 C C   . PHE A 1 300 ? 181.342 179.161 181.789 1.00 7.52  ? 328 PHE A C   1 
ATOM   2297 O O   . PHE A 1 300 ? 181.114 180.046 182.617 1.00 7.52  ? 328 PHE A O   1 
ATOM   2298 C CB  . PHE A 1 300 ? 182.196 177.001 182.686 1.00 7.52  ? 328 PHE A CB  1 
ATOM   2299 C CG  . PHE A 1 300 ? 182.931 177.771 183.744 1.00 7.52  ? 328 PHE A CG  1 
ATOM   2300 C CD1 . PHE A 1 300 ? 182.586 177.650 185.068 1.00 7.52  ? 328 PHE A CD1 1 
ATOM   2301 C CD2 . PHE A 1 300 ? 183.995 178.581 183.419 1.00 7.52  ? 328 PHE A CD2 1 
ATOM   2302 C CE1 . PHE A 1 300 ? 183.273 178.339 186.037 1.00 7.52  ? 328 PHE A CE1 1 
ATOM   2303 C CE2 . PHE A 1 300 ? 184.679 179.271 184.387 1.00 7.52  ? 328 PHE A CE2 1 
ATOM   2304 C CZ  . PHE A 1 300 ? 184.317 179.149 185.692 1.00 7.52  ? 328 PHE A CZ  1 
ATOM   2305 N N   . GLN A 1 301 ? 181.889 179.429 180.602 1.00 11.35 ? 329 GLN A N   1 
ATOM   2306 C CA  . GLN A 1 301 ? 182.230 180.800 180.245 1.00 11.35 ? 329 GLN A CA  1 
ATOM   2307 C C   . GLN A 1 301 ? 180.997 181.635 179.936 1.00 11.35 ? 329 GLN A C   1 
ATOM   2308 O O   . GLN A 1 301 ? 181.037 182.859 180.085 1.00 11.35 ? 329 GLN A O   1 
ATOM   2309 C CB  . GLN A 1 301 ? 183.182 180.819 179.050 1.00 11.35 ? 329 GLN A CB  1 
ATOM   2310 C CG  . GLN A 1 301 ? 184.597 180.349 179.353 1.00 11.35 ? 329 GLN A CG  1 
ATOM   2311 C CD  . GLN A 1 301 ? 185.410 181.368 180.129 1.00 11.35 ? 329 GLN A CD  1 
ATOM   2312 O OE1 . GLN A 1 301 ? 184.889 182.384 180.583 1.00 11.35 ? 329 GLN A OE1 1 
ATOM   2313 N NE2 . GLN A 1 301 ? 186.699 181.099 180.280 1.00 11.35 ? 329 GLN A NE2 1 
ATOM   2314 N N   . VAL A 1 302 ? 179.904 181.008 179.495 1.00 10.65 ? 330 VAL A N   1 
ATOM   2315 C CA  . VAL A 1 302 ? 178.657 181.747 179.328 1.00 10.65 ? 330 VAL A CA  1 
ATOM   2316 C C   . VAL A 1 302 ? 178.077 182.131 180.682 1.00 10.65 ? 330 VAL A C   1 
ATOM   2317 O O   . VAL A 1 302 ? 177.597 183.254 180.870 1.00 10.65 ? 330 VAL A O   1 
ATOM   2318 C CB  . VAL A 1 302 ? 177.656 180.932 178.496 1.00 10.65 ? 330 VAL A CB  1 
ATOM   2319 C CG1 . VAL A 1 302 ? 176.309 181.605 178.501 1.00 10.65 ? 330 VAL A CG1 1 
ATOM   2320 C CG2 . VAL A 1 302 ? 178.152 180.800 177.077 1.00 10.65 ? 330 VAL A CG2 1 
ATOM   2321 N N   . LEU A 1 303 ? 178.108 181.213 181.647 1.00 9.71  ? 331 LEU A N   1 
ATOM   2322 C CA  . LEU A 1 303 ? 177.552 181.503 182.961 1.00 9.71  ? 331 LEU A CA  1 
ATOM   2323 C C   . LEU A 1 303 ? 178.435 182.429 183.781 1.00 9.71  ? 331 LEU A C   1 
ATOM   2324 O O   . LEU A 1 303 ? 177.924 183.117 184.665 1.00 9.71  ? 331 LEU A O   1 
ATOM   2325 C CB  . LEU A 1 303 ? 177.317 180.210 183.733 1.00 9.71  ? 331 LEU A CB  1 
ATOM   2326 C CG  . LEU A 1 303 ? 176.112 179.381 183.305 1.00 9.71  ? 331 LEU A CG  1 
ATOM   2327 C CD1 . LEU A 1 303 ? 175.905 178.239 184.269 1.00 9.71  ? 331 LEU A CD1 1 
ATOM   2328 C CD2 . LEU A 1 303 ? 174.875 180.239 183.232 1.00 9.71  ? 331 LEU A CD2 1 
ATOM   2329 N N   . LYS A 1 304 ? 179.740 182.464 183.523 1.00 6.21  ? 332 LYS A N   1 
ATOM   2330 C CA  . LYS A 1 304 ? 180.618 183.302 184.328 1.00 6.21  ? 332 LYS A CA  1 
ATOM   2331 C C   . LYS A 1 304 ? 180.414 184.792 184.086 1.00 6.21  ? 332 LYS A C   1 
ATOM   2332 O O   . LYS A 1 304 ? 180.797 185.598 184.938 1.00 6.21  ? 332 LYS A O   1 
ATOM   2333 C CB  . LYS A 1 304 ? 182.076 182.933 184.062 1.00 6.21  ? 332 LYS A CB  1 
ATOM   2334 C CG  . LYS A 1 304 ? 183.076 183.617 184.968 1.00 6.21  ? 332 LYS A CG  1 
ATOM   2335 C CD  . LYS A 1 304 ? 182.684 183.483 186.423 1.00 6.21  ? 332 LYS A CD  1 
ATOM   2336 C CE  . LYS A 1 304 ? 183.763 184.044 187.329 1.00 6.21  ? 332 LYS A CE  1 
ATOM   2337 N NZ  . LYS A 1 304 ? 183.500 183.741 188.760 1.00 6.21  ? 332 LYS A NZ  1 
ATOM   2338 N N   . MET A 1 305 ? 179.819 185.187 182.964 1.00 11.12 ? 333 MET A N   1 
ATOM   2339 C CA  . MET A 1 305 ? 179.588 186.602 182.702 1.00 11.12 ? 333 MET A CA  1 
ATOM   2340 C C   . MET A 1 305 ? 178.228 187.083 183.185 1.00 11.12 ? 333 MET A C   1 
ATOM   2341 O O   . MET A 1 305 ? 177.961 188.285 183.137 1.00 11.12 ? 333 MET A O   1 
ATOM   2342 C CB  . MET A 1 305 ? 179.743 186.905 181.210 1.00 11.12 ? 333 MET A CB  1 
ATOM   2343 C CG  . MET A 1 305 ? 178.793 186.147 180.313 1.00 11.12 ? 333 MET A CG  1 
ATOM   2344 S SD  . MET A 1 305 ? 179.333 186.150 178.596 1.00 11.12 ? 333 MET A SD  1 
ATOM   2345 C CE  . MET A 1 305 ? 177.758 186.129 177.752 1.00 11.12 ? 333 MET A CE  1 
ATOM   2346 N N   . MET A 1 306 ? 177.369 186.182 183.655 1.00 8.88  ? 334 MET A N   1 
ATOM   2347 C CA  . MET A 1 306 ? 176.086 186.546 184.241 1.00 8.88  ? 334 MET A CA  1 
ATOM   2348 C C   . MET A 1 306 ? 176.142 186.598 185.760 1.00 8.88  ? 334 MET A C   1 
ATOM   2349 O O   . MET A 1 306 ? 175.623 187.538 186.366 1.00 8.88  ? 334 MET A O   1 
ATOM   2350 C CB  . MET A 1 306 ? 175.015 185.537 183.833 1.00 8.88  ? 334 MET A CB  1 
ATOM   2351 C CG  . MET A 1 306 ? 174.996 185.206 182.372 1.00 8.88  ? 334 MET A CG  1 
ATOM   2352 S SD  . MET A 1 306 ? 173.457 184.431 181.887 1.00 8.88  ? 334 MET A SD  1 
ATOM   2353 C CE  . MET A 1 306 ? 173.736 184.293 180.134 1.00 8.88  ? 334 MET A CE  1 
ATOM   2354 N N   . VAL A 1 307 ? 176.766 185.592 186.384 1.00 8.58  ? 335 VAL A N   1 
ATOM   2355 C CA  . VAL A 1 307 ? 176.862 185.524 187.839 1.00 8.58  ? 335 VAL A CA  1 
ATOM   2356 C C   . VAL A 1 307 ? 177.994 186.367 188.390 1.00 8.58  ? 335 VAL A C   1 
ATOM   2357 O O   . VAL A 1 307 ? 178.118 186.486 189.613 1.00 8.58  ? 335 VAL A O   1 
ATOM   2358 C CB  . VAL A 1 307 ? 177.084 184.086 188.336 1.00 8.58  ? 335 VAL A CB  1 
ATOM   2359 C CG1 . VAL A 1 307 ? 175.980 183.190 187.863 1.00 8.58  ? 335 VAL A CG1 1 
ATOM   2360 C CG2 . VAL A 1 307 ? 178.412 183.580 187.872 1.00 8.58  ? 335 VAL A CG2 1 
ATOM   2361 N N   . GLY A 1 308 ? 178.827 186.942 187.527 1.00 18.11 ? 336 GLY A N   1 
ATOM   2362 C CA  . GLY A 1 308 ? 179.917 187.791 187.959 1.00 18.11 ? 336 GLY A CA  1 
ATOM   2363 C C   . GLY A 1 308 ? 180.763 187.150 189.034 1.00 18.11 ? 336 GLY A C   1 
ATOM   2364 O O   . GLY A 1 308 ? 181.427 186.139 188.794 1.00 18.11 ? 336 GLY A O   1 
ATOM   2365 N N   . ASN A 1 309 ? 180.734 187.723 190.230 1.00 30.93 ? 337 ASN A N   1 
ATOM   2366 C CA  . ASN A 1 309 ? 181.435 187.181 191.387 1.00 30.93 ? 337 ASN A CA  1 
ATOM   2367 C C   . ASN A 1 309 ? 180.491 187.063 192.579 1.00 30.93 ? 337 ASN A C   1 
ATOM   2368 O O   . ASN A 1 309 ? 180.823 187.417 193.712 1.00 30.93 ? 337 ASN A O   1 
ATOM   2369 C CB  . ASN A 1 309 ? 182.675 188.020 191.692 1.00 30.93 ? 337 ASN A CB  1 
ATOM   2370 C CG  . ASN A 1 309 ? 182.346 189.447 192.073 1.00 30.93 ? 337 ASN A CG  1 
ATOM   2371 O OD1 . ASN A 1 309 ? 181.185 189.813 192.236 1.00 30.93 ? 337 ASN A OD1 1 
ATOM   2372 N ND2 . ASN A 1 309 ? 183.378 190.271 192.203 1.00 30.93 ? 337 ASN A ND2 1 
ATOM   2373 N N   . ASN A 1 310 ? 179.287 186.548 192.324 1.00 27.72 ? 338 ASN A N   1 
ATOM   2374 C CA  . ASN A 1 310 ? 178.342 186.222 193.383 1.00 27.72 ? 338 ASN A CA  1 
ATOM   2375 C C   . ASN A 1 310 ? 178.432 184.772 193.827 1.00 27.72 ? 338 ASN A C   1 
ATOM   2376 O O   . ASN A 1 310 ? 178.035 184.460 194.954 1.00 27.72 ? 338 ASN A O   1 
ATOM   2377 C CB  . ASN A 1 310 ? 176.915 186.523 192.931 1.00 27.72 ? 338 ASN A CB  1 
ATOM   2378 C CG  . ASN A 1 310 ? 176.705 187.983 192.634 1.00 27.72 ? 338 ASN A CG  1 
ATOM   2379 O OD1 . ASN A 1 310 ? 177.560 188.814 192.931 1.00 27.72 ? 338 ASN A OD1 1 
ATOM   2380 N ND2 . ASN A 1 310 ? 175.570 188.309 192.036 1.00 27.72 ? 338 ASN A ND2 1 
ATOM   2381 N N   . LEU A 1 311 ? 178.932 183.884 192.972 1.00 21.39 ? 339 LEU A N   1 
ATOM   2382 C CA  . LEU A 1 311 ? 179.278 182.522 193.348 1.00 21.39 ? 339 LEU A CA  1 
ATOM   2383 C C   . LEU A 1 311 ? 180.775 182.329 193.174 1.00 21.39 ? 339 LEU A C   1 
ATOM   2384 O O   . LEU A 1 311 ? 181.372 182.864 192.237 1.00 21.39 ? 339 LEU A O   1 
ATOM   2385 C CB  . LEU A 1 311 ? 178.541 181.478 192.507 1.00 21.39 ? 339 LEU A CB  1 
ATOM   2386 C CG  . LEU A 1 311 ? 177.028 181.565 192.359 1.00 21.39 ? 339 LEU A CG  1 
ATOM   2387 C CD1 . LEU A 1 311 ? 176.511 180.347 191.636 1.00 21.39 ? 339 LEU A CD1 1 
ATOM   2388 C CD2 . LEU A 1 311 ? 176.383 181.684 193.703 1.00 21.39 ? 339 LEU A CD2 1 
ATOM   2389 N N   . LYS A 1 312 ? 181.376 181.567 194.081 1.00 18.17 ? 340 LYS A N   1 
ATOM   2390 C CA  . LYS A 1 312 ? 182.764 181.175 193.915 1.00 18.17 ? 340 LYS A CA  1 
ATOM   2391 C C   . LYS A 1 312 ? 182.944 180.461 192.581 1.00 18.17 ? 340 LYS A C   1 
ATOM   2392 O O   . LYS A 1 312 ? 181.991 179.969 191.974 1.00 18.17 ? 340 LYS A O   1 
ATOM   2393 C CB  . LYS A 1 312 ? 183.202 180.253 195.051 1.00 18.17 ? 340 LYS A CB  1 
ATOM   2394 C CG  . LYS A 1 312 ? 183.105 180.843 196.439 1.00 18.17 ? 340 LYS A CG  1 
ATOM   2395 C CD  . LYS A 1 312 ? 184.460 181.298 196.930 1.00 18.17 ? 340 LYS A CD  1 
ATOM   2396 C CE  . LYS A 1 312 ? 184.450 181.472 198.435 1.00 18.17 ? 340 LYS A CE  1 
ATOM   2397 N NZ  . LYS A 1 312 ? 184.108 180.200 199.126 1.00 18.17 ? 340 LYS A NZ  1 
ATOM   2398 N N   . ASP A 1 313 ? 184.192 180.411 192.119 1.00 16.55 ? 341 ASP A N   1 
ATOM   2399 C CA  . ASP A 1 313 ? 184.481 179.703 190.878 1.00 16.55 ? 341 ASP A CA  1 
ATOM   2400 C C   . ASP A 1 313 ? 184.214 178.209 191.031 1.00 16.55 ? 341 ASP A C   1 
ATOM   2401 O O   . ASP A 1 313 ? 183.597 177.579 190.159 1.00 16.55 ? 341 ASP A O   1 
ATOM   2402 C CB  . ASP A 1 313 ? 185.931 179.968 190.478 1.00 16.55 ? 341 ASP A CB  1 
ATOM   2403 C CG  . ASP A 1 313 ? 186.261 179.454 189.103 1.00 16.55 ? 341 ASP A CG  1 
ATOM   2404 O OD1 . ASP A 1 313 ? 185.380 178.859 188.456 1.00 16.55 ? 341 ASP A OD1 1 
ATOM   2405 O OD2 . ASP A 1 313 ? 187.409 179.660 188.660 1.00 16.55 ? 341 ASP A OD2 1 
ATOM   2406 N N   . THR A 1 314 ? 184.641 177.637 192.156 1.00 15.81 ? 342 THR A N   1 
ATOM   2407 C CA  . THR A 1 314 ? 184.504 176.203 192.376 1.00 15.81 ? 342 THR A CA  1 
ATOM   2408 C C   . THR A 1 314 ? 183.041 175.771 192.445 1.00 15.81 ? 342 THR A C   1 
ATOM   2409 O O   . THR A 1 314 ? 182.678 174.715 191.913 1.00 15.81 ? 342 THR A O   1 
ATOM   2410 C CB  . THR A 1 314 ? 185.268 175.808 193.642 1.00 15.81 ? 342 THR A CB  1 
ATOM   2411 O OG1 . THR A 1 314 ? 185.162 174.397 193.847 1.00 15.81 ? 342 THR A OG1 1 
ATOM   2412 C CG2 . THR A 1 314 ? 184.756 176.549 194.864 1.00 15.81 ? 342 THR A CG2 1 
ATOM   2413 N N   . GLN A 1 315 ? 182.185 176.568 193.087 1.00 11.52 ? 343 GLN A N   1 
ATOM   2414 C CA  . GLN A 1 315 ? 180.774 176.205 193.181 1.00 11.52 ? 343 GLN A CA  1 
ATOM   2415 C C   . GLN A 1 315 ? 180.127 176.165 191.803 1.00 11.52 ? 343 GLN A C   1 
ATOM   2416 O O   . GLN A 1 315 ? 179.368 175.236 191.481 1.00 11.52 ? 343 GLN A O   1 
ATOM   2417 C CB  . GLN A 1 315 ? 180.048 177.195 194.088 1.00 11.52 ? 343 GLN A CB  1 
ATOM   2418 C CG  . GLN A 1 315 ? 180.454 177.114 195.549 1.00 11.52 ? 343 GLN A CG  1 
ATOM   2419 C CD  . GLN A 1 315 ? 180.382 178.453 196.251 1.00 11.52 ? 343 GLN A CD  1 
ATOM   2420 O OE1 . GLN A 1 315 ? 180.104 179.474 195.634 1.00 11.52 ? 343 GLN A OE1 1 
ATOM   2421 N NE2 . GLN A 1 315 ? 180.640 178.453 197.548 1.00 11.52 ? 343 GLN A NE2 1 
ATOM   2422 N N   . LEU A 1 316 ? 180.425 177.164 190.974 1.00 13.74 ? 344 LEU A N   1 
ATOM   2423 C CA  . LEU A 1 316 ? 179.884 177.198 189.622 1.00 13.74 ? 344 LEU A CA  1 
ATOM   2424 C C   . LEU A 1 316 ? 180.364 176.003 188.815 1.00 13.74 ? 344 LEU A C   1 
ATOM   2425 O O   . LEU A 1 316 ? 179.573 175.359 188.111 1.00 13.74 ? 344 LEU A O   1 
ATOM   2426 C CB  . LEU A 1 316 ? 180.280 178.508 188.945 1.00 13.74 ? 344 LEU A CB  1 
ATOM   2427 C CG  . LEU A 1 316 ? 179.812 178.783 187.522 1.00 13.74 ? 344 LEU A CG  1 
ATOM   2428 C CD1 . LEU A 1 316 ? 178.397 178.299 187.296 1.00 13.74 ? 344 LEU A CD1 1 
ATOM   2429 C CD2 . LEU A 1 316 ? 179.913 180.265 187.266 1.00 13.74 ? 344 LEU A CD2 1 
ATOM   2430 N N   . GLN A 1 317 ? 181.653 175.674 188.917 1.00 14.38 ? 345 GLN A N   1 
ATOM   2431 C CA  . GLN A 1 317 ? 182.151 174.522 188.175 1.00 14.38 ? 345 GLN A CA  1 
ATOM   2432 C C   . GLN A 1 317 ? 181.466 173.240 188.626 1.00 14.38 ? 345 GLN A C   1 
ATOM   2433 O O   . GLN A 1 317 ? 181.106 172.399 187.795 1.00 14.38 ? 345 GLN A O   1 
ATOM   2434 C CB  . GLN A 1 317 ? 183.662 174.402 188.328 1.00 14.38 ? 345 GLN A CB  1 
ATOM   2435 C CG  . GLN A 1 317 ? 184.248 173.199 187.623 1.00 14.38 ? 345 GLN A CG  1 
ATOM   2436 C CD  . GLN A 1 317 ? 184.327 173.374 186.125 1.00 14.38 ? 345 GLN A CD  1 
ATOM   2437 O OE1 . GLN A 1 317 ? 185.386 173.670 185.583 1.00 14.38 ? 345 GLN A OE1 1 
ATOM   2438 N NE2 . GLN A 1 317 ? 183.208 173.178 185.445 1.00 14.38 ? 345 GLN A NE2 1 
ATOM   2439 N N   . GLN A 1 318 ? 181.269 173.075 189.936 1.00 13.18 ? 346 GLN A N   1 
ATOM   2440 C CA  . GLN A 1 318 ? 180.655 171.851 190.442 1.00 13.18 ? 346 GLN A CA  1 
ATOM   2441 C C   . GLN A 1 318 ? 179.226 171.697 189.934 1.00 13.18 ? 346 GLN A C   1 
ATOM   2442 O O   . GLN A 1 318 ? 178.823 170.613 189.485 1.00 13.18 ? 346 GLN A O   1 
ATOM   2443 C CB  . GLN A 1 318 ? 180.686 171.842 191.970 1.00 13.18 ? 346 GLN A CB  1 
ATOM   2444 C CG  . GLN A 1 318 ? 181.980 171.331 192.566 1.00 13.18 ? 346 GLN A CG  1 
ATOM   2445 C CD  . GLN A 1 318 ? 182.261 171.920 193.929 1.00 13.18 ? 346 GLN A CD  1 
ATOM   2446 O OE1 . GLN A 1 318 ? 181.625 172.883 194.341 1.00 13.18 ? 346 GLN A OE1 1 
ATOM   2447 N NE2 . GLN A 1 318 ? 183.222 171.345 194.637 1.00 13.18 ? 346 GLN A NE2 1 
ATOM   2448 N N   . ILE A 1 319 ? 178.439 172.775 189.993 1.00 13.12 ? 347 ILE A N   1 
ATOM   2449 C CA  . ILE A 1 319 ? 177.052 172.646 189.551 1.00 13.12 ? 347 ILE A CA  1 
ATOM   2450 C C   . ILE A 1 319 ? 176.976 172.442 188.040 1.00 13.12 ? 347 ILE A C   1 
ATOM   2451 O O   . ILE A 1 319 ? 176.108 171.702 187.553 1.00 13.12 ? 347 ILE A O   1 
ATOM   2452 C CB  . ILE A 1 319 ? 176.210 173.843 190.026 1.00 13.12 ? 347 ILE A CB  1 
ATOM   2453 C CG1 . ILE A 1 319 ? 176.745 175.156 189.475 1.00 13.12 ? 347 ILE A CG1 1 
ATOM   2454 C CG2 . ILE A 1 319 ? 176.208 173.905 191.529 1.00 13.12 ? 347 ILE A CG2 1 
ATOM   2455 C CD1 . ILE A 1 319 ? 175.970 176.355 189.954 1.00 13.12 ? 347 ILE A CD1 1 
ATOM   2456 N N   . VAL A 1 320 ? 177.884 173.057 187.273 1.00 14.53 ? 348 VAL A N   1 
ATOM   2457 C CA  . VAL A 1 320 ? 177.915 172.810 185.832 1.00 14.53 ? 348 VAL A CA  1 
ATOM   2458 C C   . VAL A 1 320 ? 178.237 171.348 185.544 1.00 14.53 ? 348 VAL A C   1 
ATOM   2459 O O   . VAL A 1 320 ? 177.627 170.720 184.667 1.00 14.53 ? 348 VAL A O   1 
ATOM   2460 C CB  . VAL A 1 320 ? 178.922 173.752 185.151 1.00 14.53 ? 348 VAL A CB  1 
ATOM   2461 C CG1 . VAL A 1 320 ? 179.159 173.320 183.730 1.00 14.53 ? 348 VAL A CG1 1 
ATOM   2462 C CG2 . VAL A 1 320 ? 178.412 175.172 185.180 1.00 14.53 ? 348 VAL A CG2 1 
ATOM   2463 N N   . ASP A 1 321 ? 179.210 170.790 186.270 1.00 14.51 ? 349 ASP A N   1 
ATOM   2464 C CA  . ASP A 1 321 ? 179.560 169.383 186.103 1.00 14.51 ? 349 ASP A CA  1 
ATOM   2465 C C   . ASP A 1 321 ? 178.356 168.490 186.346 1.00 14.51 ? 349 ASP A C   1 
ATOM   2466 O O   . ASP A 1 321 ? 178.071 167.580 185.559 1.00 14.51 ? 349 ASP A O   1 
ATOM   2467 C CB  . ASP A 1 321 ? 180.688 169.009 187.061 1.00 14.51 ? 349 ASP A CB  1 
ATOM   2468 C CG  . ASP A 1 321 ? 182.045 169.132 186.432 1.00 14.51 ? 349 ASP A CG  1 
ATOM   2469 O OD1 . ASP A 1 321 ? 182.153 168.902 185.213 1.00 14.51 ? 349 ASP A OD1 1 
ATOM   2470 O OD2 . ASP A 1 321 ? 183.011 169.446 187.154 1.00 14.51 ? 349 ASP A OD2 1 
ATOM   2471 N N   . LYS A 1 322 ? 177.644 168.731 187.446 1.00 16.05 ? 350 LYS A N   1 
ATOM   2472 C CA  . LYS A 1 322 ? 176.497 167.888 187.768 1.00 16.05 ? 350 LYS A CA  1 
ATOM   2473 C C   . LYS A 1 322 ? 175.410 168.011 186.708 1.00 16.05 ? 350 LYS A C   1 
ATOM   2474 O O   . LYS A 1 322 ? 174.787 167.011 186.329 1.00 16.05 ? 350 LYS A O   1 
ATOM   2475 C CB  . LYS A 1 322 ? 175.957 168.248 189.147 1.00 16.05 ? 350 LYS A CB  1 
ATOM   2476 C CG  . LYS A 1 322 ? 176.955 167.987 190.252 1.00 16.05 ? 350 LYS A CG  1 
ATOM   2477 C CD  . LYS A 1 322 ? 176.411 168.375 191.603 1.00 16.05 ? 350 LYS A CD  1 
ATOM   2478 C CE  . LYS A 1 322 ? 177.421 168.066 192.678 1.00 16.05 ? 350 LYS A CE  1 
ATOM   2479 N NZ  . LYS A 1 322 ? 178.622 168.924 192.526 1.00 16.05 ? 350 LYS A NZ  1 
ATOM   2480 N N   . THR A 1 323 ? 175.176 169.229 186.208 1.00 16.98 ? 351 THR A N   1 
ATOM   2481 C CA  . THR A 1 323 ? 174.179 169.417 185.156 1.00 16.98 ? 351 THR A CA  1 
ATOM   2482 C C   . THR A 1 323 ? 174.536 168.620 183.910 1.00 16.98 ? 351 THR A C   1 
ATOM   2483 O O   . THR A 1 323 ? 173.696 167.900 183.354 1.00 16.98 ? 351 THR A O   1 
ATOM   2484 C CB  . THR A 1 323 ? 174.050 170.896 184.805 1.00 16.98 ? 351 THR A CB  1 
ATOM   2485 O OG1 . THR A 1 323 ? 173.312 171.569 185.829 1.00 16.98 ? 351 THR A OG1 1 
ATOM   2486 C CG2 . THR A 1 323 ? 173.327 171.055 183.483 1.00 16.98 ? 351 THR A CG2 1 
ATOM   2487 N N   . ILE A 1 324 ? 175.786 168.733 183.456 1.00 19.24 ? 352 ILE A N   1 
ATOM   2488 C CA  . ILE A 1 324 ? 176.194 168.029 182.243 1.00 19.24 ? 352 ILE A CA  1 
ATOM   2489 C C   . ILE A 1 324 ? 176.097 166.522 182.442 1.00 19.24 ? 352 ILE A C   1 
ATOM   2490 O O   . ILE A 1 324 ? 175.635 165.794 181.555 1.00 19.24 ? 352 ILE A O   1 
ATOM   2491 C CB  . ILE A 1 324 ? 177.609 168.459 181.817 1.00 19.24 ? 352 ILE A CB  1 
ATOM   2492 C CG1 . ILE A 1 324 ? 177.555 169.784 181.059 1.00 19.24 ? 352 ILE A CG1 1 
ATOM   2493 C CG2 . ILE A 1 324 ? 178.254 167.399 180.956 1.00 19.24 ? 352 ILE A CG2 1 
ATOM   2494 C CD1 . ILE A 1 324 ? 178.890 170.238 180.532 1.00 19.24 ? 352 ILE A CD1 1 
ATOM   2495 N N   . ILE A 1 325 ? 176.514 166.031 183.612 1.00 20.61 ? 353 ILE A N   1 
ATOM   2496 C CA  . ILE A 1 325 ? 176.488 164.591 183.864 1.00 20.61 ? 353 ILE A CA  1 
ATOM   2497 C C   . ILE A 1 325 ? 175.055 164.071 183.872 1.00 20.61 ? 353 ILE A C   1 
ATOM   2498 O O   . ILE A 1 325 ? 174.773 162.983 183.357 1.00 20.61 ? 353 ILE A O   1 
ATOM   2499 C CB  . ILE A 1 325 ? 177.226 164.265 185.174 1.00 20.61 ? 353 ILE A CB  1 
ATOM   2500 C CG1 . ILE A 1 325 ? 178.734 164.252 184.937 1.00 20.61 ? 353 ILE A CG1 1 
ATOM   2501 C CG2 . ILE A 1 325 ? 176.781 162.928 185.729 1.00 20.61 ? 353 ILE A CG2 1 
ATOM   2502 C CD1 . ILE A 1 325 ? 179.540 164.171 186.203 1.00 20.61 ? 353 ILE A CD1 1 
ATOM   2503 N N   . ASN A 1 326 ? 174.126 164.834 184.447 1.00 24.26 ? 354 ASN A N   1 
ATOM   2504 C CA  . ASN A 1 326 ? 172.733 164.405 184.433 1.00 24.26 ? 354 ASN A CA  1 
ATOM   2505 C C   . ASN A 1 326 ? 172.037 164.653 183.101 1.00 24.26 ? 354 ASN A C   1 
ATOM   2506 O O   . ASN A 1 326 ? 170.937 164.131 182.897 1.00 24.26 ? 354 ASN A O   1 
ATOM   2507 C CB  . ASN A 1 326 ? 171.948 165.095 185.552 1.00 24.26 ? 354 ASN A CB  1 
ATOM   2508 C CG  . ASN A 1 326 ? 172.295 164.557 186.928 1.00 24.26 ? 354 ASN A CG  1 
ATOM   2509 O OD1 . ASN A 1 326 ? 172.434 163.349 187.118 1.00 24.26 ? 354 ASN A OD1 1 
ATOM   2510 N ND2 . ASN A 1 326 ? 172.435 165.454 187.896 1.00 24.26 ? 354 ASN A ND2 1 
ATOM   2511 N N   . ALA A 1 327 ? 172.635 165.430 182.195 1.00 31.22 ? 355 ALA A N   1 
ATOM   2512 C CA  . ALA A 1 327 ? 172.001 165.715 180.912 1.00 31.22 ? 355 ALA A CA  1 
ATOM   2513 C C   . ALA A 1 327 ? 172.477 164.825 179.772 1.00 31.22 ? 355 ALA A C   1 
ATOM   2514 O O   . ALA A 1 327 ? 171.799 164.758 178.742 1.00 31.22 ? 355 ALA A O   1 
ATOM   2515 C CB  . ALA A 1 327 ? 172.226 167.179 180.519 1.00 31.22 ? 355 ALA A CB  1 
ATOM   2516 N N   . ASP A 1 328 ? 173.613 164.146 179.923 1.00 38.03 ? 356 ASP A N   1 
ATOM   2517 C CA  . ASP A 1 328 ? 174.145 163.291 178.864 1.00 38.03 ? 356 ASP A CA  1 
ATOM   2518 C C   . ASP A 1 328 ? 173.268 162.057 178.705 1.00 38.03 ? 356 ASP A C   1 
ATOM   2519 O O   . ASP A 1 328 ? 173.250 161.181 179.575 1.00 38.03 ? 356 ASP A O   1 
ATOM   2520 C CB  . ASP A 1 328 ? 175.581 162.886 179.180 1.00 38.03 ? 356 ASP A CB  1 
ATOM   2521 C CG  . ASP A 1 328 ? 176.594 163.858 178.632 1.00 38.03 ? 356 ASP A CG  1 
ATOM   2522 O OD1 . ASP A 1 328 ? 176.344 164.427 177.551 1.00 38.03 ? 356 ASP A OD1 1 
ATOM   2523 O OD2 . ASP A 1 328 ? 177.642 164.050 179.281 1.00 38.03 ? 356 ASP A OD2 1 
ATOM   2524 N N   . LYS A 1 329 ? 172.547 161.977 177.589 1.00 44.55 ? 357 LYS A N   1 
ATOM   2525 C CA  . LYS A 1 329 ? 171.746 160.806 177.265 1.00 44.55 ? 357 LYS A CA  1 
ATOM   2526 C C   . LYS A 1 329 ? 172.401 159.925 176.208 1.00 44.55 ? 357 LYS A C   1 
ATOM   2527 O O   . LYS A 1 329 ? 171.790 158.948 175.766 1.00 44.55 ? 357 LYS A O   1 
ATOM   2528 C CB  . LYS A 1 329 ? 170.352 161.233 176.803 1.00 44.55 ? 357 LYS A CB  1 
ATOM   2529 C CG  . LYS A 1 329 ? 169.537 162.027 177.828 1.00 44.55 ? 357 LYS A CG  1 
ATOM   2530 C CD  . LYS A 1 329 ? 169.059 161.185 179.013 1.00 44.55 ? 357 LYS A CD  1 
ATOM   2531 C CE  . LYS A 1 329 ? 170.013 161.251 180.203 1.00 44.55 ? 357 LYS A CE  1 
ATOM   2532 N NZ  . LYS A 1 329 ? 169.490 160.519 181.390 1.00 44.55 ? 357 LYS A NZ  1 
ATOM   2533 N N   . ASP A 1 330 ? 173.626 160.251 175.790 1.00 53.81 ? 358 ASP A N   1 
ATOM   2534 C CA  . ASP A 1 330 ? 174.344 159.437 174.820 1.00 53.81 ? 358 ASP A CA  1 
ATOM   2535 C C   . ASP A 1 330 ? 175.815 159.235 175.157 1.00 53.81 ? 358 ASP A C   1 
ATOM   2536 O O   . ASP A 1 330 ? 176.511 158.560 174.394 1.00 53.81 ? 358 ASP A O   1 
ATOM   2537 C CB  . ASP A 1 330 ? 174.225 160.046 173.412 1.00 53.81 ? 358 ASP A CB  1 
ATOM   2538 C CG  . ASP A 1 330 ? 174.707 161.481 173.352 1.00 53.81 ? 358 ASP A CG  1 
ATOM   2539 O OD1 . ASP A 1 330 ? 175.025 162.049 174.416 1.00 53.81 ? 358 ASP A OD1 1 
ATOM   2540 O OD2 . ASP A 1 330 ? 174.770 162.043 172.238 1.00 53.81 ? 358 ASP A OD2 1 
ATOM   2541 N N   . GLY A 1 331 ? 176.313 159.800 176.253 1.00 45.15 ? 359 GLY A N   1 
ATOM   2542 C CA  . GLY A 1 331 ? 177.675 159.553 176.678 1.00 45.15 ? 359 GLY A CA  1 
ATOM   2543 C C   . GLY A 1 331 ? 178.742 160.359 175.975 1.00 45.15 ? 359 GLY A C   1 
ATOM   2544 O O   . GLY A 1 331 ? 179.929 160.119 176.216 1.00 45.15 ? 359 GLY A O   1 
ATOM   2545 N N   . ASP A 1 332 ? 178.365 161.306 175.114 1.00 49.93 ? 360 ASP A N   1 
ATOM   2546 C CA  . ASP A 1 332 ? 179.367 162.098 174.405 1.00 49.93 ? 360 ASP A CA  1 
ATOM   2547 C C   . ASP A 1 332 ? 180.127 163.018 175.353 1.00 49.93 ? 360 ASP A C   1 
ATOM   2548 O O   . ASP A 1 332 ? 181.342 163.200 175.209 1.00 49.93 ? 360 ASP A O   1 
ATOM   2549 C CB  . ASP A 1 332 ? 178.705 162.903 173.287 1.00 49.93 ? 360 ASP A CB  1 
ATOM   2550 C CG  . ASP A 1 332 ? 177.482 163.670 173.759 1.00 49.93 ? 360 ASP A CG  1 
ATOM   2551 O OD1 . ASP A 1 332 ? 177.286 163.801 174.984 1.00 49.93 ? 360 ASP A OD1 1 
ATOM   2552 O OD2 . ASP A 1 332 ? 176.706 164.134 172.898 1.00 49.93 ? 360 ASP A OD2 1 
ATOM   2553 N N   . GLY A 1 333 ? 179.434 163.599 176.329 1.00 46.03 ? 361 GLY A N   1 
ATOM   2554 C CA  . GLY A 1 333 ? 180.018 164.579 177.220 1.00 46.03 ? 361 GLY A CA  1 
ATOM   2555 C C   . GLY A 1 333 ? 179.674 166.015 176.893 1.00 46.03 ? 361 GLY A C   1 
ATOM   2556 O O   . GLY A 1 333 ? 180.180 166.923 177.562 1.00 46.03 ? 361 GLY A O   1 
ATOM   2557 N N   . ARG A 1 334 ? 178.841 166.246 175.881 1.00 42.14 ? 362 ARG A N   1 
ATOM   2558 C CA  . ARG A 1 334 ? 178.430 167.578 175.470 1.00 42.14 ? 362 ARG A CA  1 
ATOM   2559 C C   . ARG A 1 334 ? 176.978 167.508 175.022 1.00 42.14 ? 362 ARG A C   1 
ATOM   2560 O O   . ARG A 1 334 ? 176.583 166.564 174.334 1.00 42.14 ? 362 ARG A O   1 
ATOM   2561 C CB  . ARG A 1 334 ? 179.319 168.109 174.337 1.00 42.14 ? 362 ARG A CB  1 
ATOM   2562 C CG  . ARG A 1 334 ? 180.785 168.266 174.726 1.00 42.14 ? 362 ARG A CG  1 
ATOM   2563 C CD  . ARG A 1 334 ? 181.671 168.559 173.528 1.00 42.14 ? 362 ARG A CD  1 
ATOM   2564 N NE  . ARG A 1 334 ? 181.683 167.450 172.581 1.00 42.14 ? 362 ARG A NE  1 
ATOM   2565 C CZ  . ARG A 1 334 ? 181.463 167.581 171.278 1.00 42.14 ? 362 ARG A CZ  1 
ATOM   2566 N NH1 . ARG A 1 334 ? 181.233 168.779 170.762 1.00 42.14 ? 362 ARG A NH1 1 
ATOM   2567 N NH2 . ARG A 1 334 ? 181.487 166.516 170.489 1.00 42.14 ? 362 ARG A NH2 1 
ATOM   2568 N N   . ILE A 1 335 ? 176.188 168.500 175.414 1.00 36.71 ? 363 ILE A N   1 
ATOM   2569 C CA  . ILE A 1 335 ? 174.745 168.468 175.203 1.00 36.71 ? 363 ILE A CA  1 
ATOM   2570 C C   . ILE A 1 335 ? 174.433 168.885 173.772 1.00 36.71 ? 363 ILE A C   1 
ATOM   2571 O O   . ILE A 1 335 ? 174.972 169.879 173.272 1.00 36.71 ? 363 ILE A O   1 
ATOM   2572 C CB  . ILE A 1 335 ? 174.019 169.372 176.212 1.00 36.71 ? 363 ILE A CB  1 
ATOM   2573 C CG1 . ILE A 1 335 ? 174.301 168.918 177.639 1.00 36.71 ? 363 ILE A CG1 1 
ATOM   2574 C CG2 . ILE A 1 335 ? 172.526 169.353 175.971 1.00 36.71 ? 363 ILE A CG2 1 
ATOM   2575 C CD1 . ILE A 1 335 ? 175.319 169.760 178.339 1.00 36.71 ? 363 ILE A CD1 1 
ATOM   2576 N N   . SER A 1 336 ? 173.570 168.118 173.109 1.00 40.67 ? 364 SER A N   1 
ATOM   2577 C CA  . SER A 1 336 ? 173.068 168.464 171.791 1.00 40.67 ? 364 SER A CA  1 
ATOM   2578 C C   . SER A 1 336 ? 171.749 169.216 171.929 1.00 40.67 ? 364 SER A C   1 
ATOM   2579 O O   . SER A 1 336 ? 171.280 169.499 173.032 1.00 40.67 ? 364 SER A O   1 
ATOM   2580 C CB  . SER A 1 336 ? 172.886 167.213 170.938 1.00 40.67 ? 364 SER A CB  1 
ATOM   2581 O OG  . SER A 1 336 ? 171.620 166.624 171.175 1.00 40.67 ? 364 SER A OG  1 
ATOM   2582 N N   . PHE A 1 337 ? 171.127 169.539 170.794 1.00 42.89 ? 365 PHE A N   1 
ATOM   2583 C CA  . PHE A 1 337 ? 169.859 170.257 170.856 1.00 42.89 ? 365 PHE A CA  1 
ATOM   2584 C C   . PHE A 1 337 ? 168.717 169.358 171.308 1.00 42.89 ? 365 PHE A C   1 
ATOM   2585 O O   . PHE A 1 337 ? 167.779 169.836 171.951 1.00 42.89 ? 365 PHE A O   1 
ATOM   2586 C CB  . PHE A 1 337 ? 169.519 170.886 169.508 1.00 42.89 ? 365 PHE A CB  1 
ATOM   2587 C CG  . PHE A 1 337 ? 168.328 171.797 169.559 1.00 42.89 ? 365 PHE A CG  1 
ATOM   2588 C CD1 . PHE A 1 337 ? 168.462 173.108 169.971 1.00 42.89 ? 365 PHE A CD1 1 
ATOM   2589 C CD2 . PHE A 1 337 ? 167.070 171.336 169.215 1.00 42.89 ? 365 PHE A CD2 1 
ATOM   2590 C CE1 . PHE A 1 337 ? 167.367 173.945 170.027 1.00 42.89 ? 365 PHE A CE1 1 
ATOM   2591 C CE2 . PHE A 1 337 ? 165.973 172.168 169.271 1.00 42.89 ? 365 PHE A CE2 1 
ATOM   2592 C CZ  . PHE A 1 337 ? 166.123 173.474 169.677 1.00 42.89 ? 365 PHE A CZ  1 
ATOM   2593 N N   . GLU A 1 338 ? 168.758 168.069 170.969 1.00 48.66 ? 366 GLU A N   1 
ATOM   2594 C CA  . GLU A 1 338 ? 167.701 167.172 171.425 1.00 48.66 ? 366 GLU A CA  1 
ATOM   2595 C C   . GLU A 1 338 ? 167.740 166.998 172.939 1.00 48.66 ? 366 GLU A C   1 
ATOM   2596 O O   . GLU A 1 338 ? 166.696 167.017 173.599 1.00 48.66 ? 366 GLU A O   1 
ATOM   2597 C CB  . GLU A 1 338 ? 167.813 165.821 170.724 1.00 48.66 ? 366 GLU A CB  1 
ATOM   2598 C CG  . GLU A 1 338 ? 166.826 164.784 171.234 1.00 48.66 ? 366 GLU A CG  1 
ATOM   2599 C CD  . GLU A 1 338 ? 165.423 165.338 171.386 1.00 48.66 ? 366 GLU A CD  1 
ATOM   2600 O OE1 . GLU A 1 338 ? 164.920 165.964 170.430 1.00 48.66 ? 366 GLU A OE1 1 
ATOM   2601 O OE2 . GLU A 1 338 ? 164.825 165.152 172.467 1.00 48.66 ? 366 GLU A OE2 1 
ATOM   2602 N N   . GLU A 1 339 ? 168.936 166.839 173.509 1.00 43.51 ? 367 GLU A N   1 
ATOM   2603 C CA  . GLU A 1 339 ? 169.050 166.750 174.961 1.00 43.51 ? 367 GLU A CA  1 
ATOM   2604 C C   . GLU A 1 339 ? 168.613 168.052 175.624 1.00 43.51 ? 367 GLU A C   1 
ATOM   2605 O O   . GLU A 1 339 ? 167.975 168.037 176.684 1.00 43.51 ? 367 GLU A O   1 
ATOM   2606 C CB  . GLU A 1 339 ? 170.485 166.395 175.347 1.00 43.51 ? 367 GLU A CB  1 
ATOM   2607 C CG  . GLU A 1 339 ? 170.965 165.060 174.795 1.00 43.51 ? 367 GLU A CG  1 
ATOM   2608 C CD  . GLU A 1 339 ? 172.467 165.020 174.586 1.00 43.51 ? 367 GLU A CD  1 
ATOM   2609 O OE1 . GLU A 1 339 ? 173.013 165.984 174.014 1.00 43.51 ? 367 GLU A OE1 1 
ATOM   2610 O OE2 . GLU A 1 339 ? 173.103 164.028 174.994 1.00 43.51 ? 367 GLU A OE2 1 
ATOM   2611 N N   . PHE A 1 340 ? 168.950 169.188 175.010 1.00 40.23 ? 368 PHE A N   1 
ATOM   2612 C CA  . PHE A 1 340 ? 168.503 170.480 175.520 1.00 40.23 ? 368 PHE A CA  1 
ATOM   2613 C C   . PHE A 1 340 ? 166.981 170.571 175.528 1.00 40.23 ? 368 PHE A C   1 
ATOM   2614 O O   . PHE A 1 340 ? 166.376 170.951 176.535 1.00 40.23 ? 368 PHE A O   1 
ATOM   2615 C CB  . PHE A 1 340 ? 169.114 171.597 174.674 1.00 40.23 ? 368 PHE A CB  1 
ATOM   2616 C CG  . PHE A 1 340 ? 168.730 172.982 175.107 1.00 40.23 ? 368 PHE A CG  1 
ATOM   2617 C CD1 . PHE A 1 340 ? 169.548 173.703 175.950 1.00 40.23 ? 368 PHE A CD1 1 
ATOM   2618 C CD2 . PHE A 1 340 ? 167.568 173.572 174.648 1.00 40.23 ? 368 PHE A CD2 1 
ATOM   2619 C CE1 . PHE A 1 340 ? 169.206 174.976 176.341 1.00 40.23 ? 368 PHE A CE1 1 
ATOM   2620 C CE2 . PHE A 1 340 ? 167.223 174.843 175.039 1.00 40.23 ? 368 PHE A CE2 1 
ATOM   2621 C CZ  . PHE A 1 340 ? 168.042 175.545 175.885 1.00 40.23 ? 368 PHE A CZ  1 
ATOM   2622 N N   . CYS A 1 341 ? 166.343 170.217 174.411 1.00 45.24 ? 369 CYS A N   1 
ATOM   2623 C CA  . CYS A 1 341 ? 164.888 170.253 174.336 1.00 45.24 ? 369 CYS A CA  1 
ATOM   2624 C C   . CYS A 1 341 ? 164.239 169.190 175.210 1.00 45.24 ? 369 CYS A C   1 
ATOM   2625 O O   . CYS A 1 341 ? 163.032 169.260 175.457 1.00 45.24 ? 369 CYS A O   1 
ATOM   2626 C CB  . CYS A 1 341 ? 164.431 170.086 172.888 1.00 45.24 ? 369 CYS A CB  1 
ATOM   2627 S SG  . CYS A 1 341 ? 162.774 170.714 172.551 1.00 45.24 ? 369 CYS A SG  1 
ATOM   2628 N N   . ALA A 1 342 ? 164.998 168.184 175.639 1.00 45.23 ? 370 ALA A N   1 
ATOM   2629 C CA  . ALA A 1 342 ? 164.503 167.283 176.673 1.00 45.23 ? 370 ALA A CA  1 
ATOM   2630 C C   . ALA A 1 342 ? 164.573 167.934 178.049 1.00 45.23 ? 370 ALA A C   1 
ATOM   2631 O O   . ALA A 1 342 ? 163.665 167.761 178.868 1.00 45.23 ? 370 ALA A O   1 
ATOM   2632 C CB  . ALA A 1 342 ? 165.294 165.976 176.657 1.00 45.23 ? 370 ALA A CB  1 
ATOM   2633 N N   . VAL A 1 343 ? 165.642 168.686 178.314 1.00 41.55 ? 371 VAL A N   1 
ATOM   2634 C CA  . VAL A 1 343 ? 165.780 169.367 179.600 1.00 41.55 ? 371 VAL A CA  1 
ATOM   2635 C C   . VAL A 1 343 ? 164.825 170.552 179.677 1.00 41.55 ? 371 VAL A C   1 
ATOM   2636 O O   . VAL A 1 343 ? 163.947 170.613 180.545 1.00 41.55 ? 371 VAL A O   1 
ATOM   2637 C CB  . VAL A 1 343 ? 167.238 169.803 179.823 1.00 41.55 ? 371 VAL A CB  1 
ATOM   2638 C CG1 . VAL A 1 343 ? 167.315 170.876 180.890 1.00 41.55 ? 371 VAL A CG1 1 
ATOM   2639 C CG2 . VAL A 1 343 ? 168.094 168.609 180.203 1.00 41.55 ? 371 VAL A CG2 1 
ATOM   2640 N N   . VAL A 1 344 ? 164.984 171.510 178.770 1.00 41.20 ? 372 VAL A N   1 
ATOM   2641 C CA  . VAL A 1 344 ? 164.091 172.654 178.686 1.00 41.20 ? 372 VAL A CA  1 
ATOM   2642 C C   . VAL A 1 344 ? 162.960 172.308 177.724 1.00 41.20 ? 372 VAL A C   1 
ATOM   2643 O O   . VAL A 1 344 ? 163.118 171.498 176.812 1.00 41.20 ? 372 VAL A O   1 
ATOM   2644 C CB  . VAL A 1 344 ? 164.858 173.918 178.245 1.00 41.20 ? 372 VAL A CB  1 
ATOM   2645 C CG1 . VAL A 1 344 ? 163.926 175.095 178.053 1.00 41.20 ? 372 VAL A CG1 1 
ATOM   2646 C CG2 . VAL A 1 344 ? 165.929 174.251 179.261 1.00 41.20 ? 372 VAL A CG2 1 
ATOM   2647 N N   . GLY A 1 345 ? 161.808 172.938 177.917 1.00 49.03 ? 373 GLY A N   1 
ATOM   2648 C CA  . GLY A 1 345 ? 160.596 172.506 177.254 1.00 49.03 ? 373 GLY A CA  1 
ATOM   2649 C C   . GLY A 1 345 ? 159.590 172.067 178.293 1.00 49.03 ? 373 GLY A C   1 
ATOM   2650 O O   . GLY A 1 345 ? 159.702 170.983 178.872 1.00 49.03 ? 373 GLY A O   1 
ATOM   2651 N N   . GLY A 1 346 ? 158.596 172.922 178.535 1.00 56.35 ? 374 GLY A N   1 
ATOM   2652 C CA  . GLY A 1 346 ? 157.761 172.863 179.721 1.00 56.35 ? 374 GLY A CA  1 
ATOM   2653 C C   . GLY A 1 346 ? 157.902 174.098 180.586 1.00 56.35 ? 374 GLY A C   1 
ATOM   2654 O O   . GLY A 1 346 ? 156.950 174.484 181.273 1.00 56.35 ? 374 GLY A O   1 
ATOM   2655 N N   . LEU A 1 347 ? 159.079 174.724 180.563 1.00 52.58 ? 375 LEU A N   1 
ATOM   2656 C CA  . LEU A 1 347 ? 159.224 176.056 181.134 1.00 52.58 ? 375 LEU A CA  1 
ATOM   2657 C C   . LEU A 1 347 ? 158.365 177.066 180.389 1.00 52.58 ? 375 LEU A C   1 
ATOM   2658 O O   . LEU A 1 347 ? 157.941 178.070 180.972 1.00 52.58 ? 375 LEU A O   1 
ATOM   2659 C CB  . LEU A 1 347 ? 160.689 176.495 181.092 1.00 52.58 ? 375 LEU A CB  1 
ATOM   2660 C CG  . LEU A 1 347 ? 161.647 176.065 182.201 1.00 52.58 ? 375 LEU A CG  1 
ATOM   2661 C CD1 . LEU A 1 347 ? 161.881 174.566 182.176 1.00 52.58 ? 375 LEU A CD1 1 
ATOM   2662 C CD2 . LEU A 1 347 ? 162.957 176.812 182.059 1.00 52.58 ? 375 LEU A CD2 1 
ATOM   2663 N N   . ASP A 1 348 ? 158.099 176.813 179.107 1.00 59.80 ? 376 ASP A N   1 
ATOM   2664 C CA  . ASP A 1 348 ? 157.388 177.747 178.238 1.00 59.80 ? 376 ASP A CA  1 
ATOM   2665 C C   . ASP A 1 348 ? 158.083 179.109 178.238 1.00 59.80 ? 376 ASP A C   1 
ATOM   2666 O O   . ASP A 1 348 ? 157.523 180.128 178.642 1.00 59.80 ? 376 ASP A O   1 
ATOM   2667 C CB  . ASP A 1 348 ? 155.916 177.871 178.647 1.00 59.80 ? 376 ASP A CB  1 
ATOM   2668 C CG  . ASP A 1 348 ? 155.027 178.313 177.501 1.00 59.80 ? 376 ASP A CG  1 
ATOM   2669 O OD1 . ASP A 1 348 ? 154.002 177.645 177.252 1.00 59.80 ? 376 ASP A OD1 1 
ATOM   2670 O OD2 . ASP A 1 348 ? 155.349 179.330 176.852 1.00 59.80 ? 376 ASP A OD2 1 
ATOM   2671 N N   . ILE A 1 349 ? 159.343 179.101 177.790 1.00 51.92 ? 377 ILE A N   1 
ATOM   2672 C CA  . ILE A 1 349 ? 160.120 180.334 177.706 1.00 51.92 ? 377 ILE A CA  1 
ATOM   2673 C C   . ILE A 1 349 ? 160.002 180.993 176.339 1.00 51.92 ? 377 ILE A C   1 
ATOM   2674 O O   . ILE A 1 349 ? 160.343 182.178 176.198 1.00 51.92 ? 377 ILE A O   1 
ATOM   2675 C CB  . ILE A 1 349 ? 161.600 180.062 178.040 1.00 51.92 ? 377 ILE A CB  1 
ATOM   2676 C CG1 . ILE A 1 349 ? 162.340 181.373 178.297 1.00 51.92 ? 377 ILE A CG1 1 
ATOM   2677 C CG2 . ILE A 1 349 ? 162.261 179.308 176.902 1.00 51.92 ? 377 ILE A CG2 1 
ATOM   2678 C CD1 . ILE A 1 349 ? 161.851 182.105 179.522 1.00 51.92 ? 377 ILE A CD1 1 
ATOM   2679 N N   . HIS A 1 350 ? 159.499 180.278 175.333 1.00 56.30 ? 378 HIS A N   1 
ATOM   2680 C CA  . HIS A 1 350 ? 159.312 180.876 174.019 1.00 56.30 ? 378 HIS A CA  1 
ATOM   2681 C C   . HIS A 1 350 ? 158.288 182.001 174.043 1.00 56.30 ? 378 HIS A C   1 
ATOM   2682 O O   . HIS A 1 350 ? 158.218 182.782 173.089 1.00 56.30 ? 378 HIS A O   1 
ATOM   2683 C CB  . HIS A 1 350 ? 158.888 179.806 173.015 1.00 56.30 ? 378 HIS A CB  1 
ATOM   2684 C CG  . HIS A 1 350 ? 157.547 179.208 173.302 1.00 56.30 ? 378 HIS A CG  1 
ATOM   2685 N ND1 . HIS A 1 350 ? 156.366 179.847 172.995 1.00 56.30 ? 378 HIS A ND1 1 
ATOM   2686 C CD2 . HIS A 1 350 ? 157.200 178.035 173.882 1.00 56.30 ? 378 HIS A CD2 1 
ATOM   2687 C CE1 . HIS A 1 350 ? 155.349 179.090 173.365 1.00 56.30 ? 378 HIS A CE1 1 
ATOM   2688 N NE2 . HIS A 1 350 ? 155.828 177.984 173.906 1.00 56.30 ? 378 HIS A NE2 1 
ATOM   2689 N N   . LYS A 1 351 ? 157.487 182.097 175.102 1.00 50.50 ? 379 LYS A N   1 
ATOM   2690 C CA  . LYS A 1 351 ? 156.526 183.181 175.236 1.00 50.50 ? 379 LYS A CA  1 
ATOM   2691 C C   . LYS A 1 351 ? 157.142 184.451 175.802 1.00 50.50 ? 379 LYS A C   1 
ATOM   2692 O O   . LYS A 1 351 ? 156.474 185.490 175.813 1.00 50.50 ? 379 LYS A O   1 
ATOM   2693 C CB  . LYS A 1 351 ? 155.367 182.747 176.133 1.00 50.50 ? 379 LYS A CB  1 
ATOM   2694 C CG  . LYS A 1 351 ? 155.778 182.539 177.576 1.00 50.50 ? 379 LYS A CG  1 
ATOM   2695 C CD  . LYS A 1 351 ? 154.615 182.090 178.439 1.00 50.50 ? 379 LYS A CD  1 
ATOM   2696 C CE  . LYS A 1 351 ? 155.062 181.847 179.872 1.00 50.50 ? 379 LYS A CE  1 
ATOM   2697 N NZ  . LYS A 1 351 ? 155.482 183.104 180.551 1.00 50.50 ? 379 LYS A NZ  1 
ATOM   2698 N N   . LYS A 1 352 ? 158.385 184.396 176.275 1.00 47.70 ? 380 LYS A N   1 
ATOM   2699 C CA  . LYS A 1 352 ? 159.033 185.547 176.885 1.00 47.70 ? 380 LYS A CA  1 
ATOM   2700 C C   . LYS A 1 352 ? 159.936 186.301 175.914 1.00 47.70 ? 380 LYS A C   1 
ATOM   2701 O O   . LYS A 1 352 ? 160.380 187.408 176.233 1.00 47.70 ? 380 LYS A O   1 
ATOM   2702 C CB  . LYS A 1 352 ? 159.825 185.098 178.122 1.00 47.70 ? 380 LYS A CB  1 
ATOM   2703 C CG  . LYS A 1 352 ? 160.420 186.229 178.951 1.00 47.70 ? 380 LYS A CG  1 
ATOM   2704 C CD  . LYS A 1 352 ? 161.170 185.712 180.166 1.00 47.70 ? 380 LYS A CD  1 
ATOM   2705 C CE  . LYS A 1 352 ? 160.214 185.173 181.212 1.00 47.70 ? 380 LYS A CE  1 
ATOM   2706 N NZ  . LYS A 1 352 ? 159.382 186.257 181.804 1.00 47.70 ? 380 LYS A NZ  1 
ATOM   2707 N N   . MET A 1 353 ? 160.185 185.758 174.727 1.00 40.19 ? 381 MET A N   1 
ATOM   2708 C CA  . MET A 1 353 ? 160.990 186.425 173.705 1.00 40.19 ? 381 MET A CA  1 
ATOM   2709 C C   . MET A 1 353 ? 160.031 186.954 172.645 1.00 40.19 ? 381 MET A C   1 
ATOM   2710 O O   . MET A 1 353 ? 159.718 186.269 171.672 1.00 40.19 ? 381 MET A O   1 
ATOM   2711 C CB  . MET A 1 353 ? 162.020 185.480 173.099 1.00 40.19 ? 381 MET A CB  1 
ATOM   2712 C CG  . MET A 1 353 ? 163.138 185.084 174.041 1.00 40.19 ? 381 MET A CG  1 
ATOM   2713 S SD  . MET A 1 353 ? 164.086 183.686 173.420 1.00 40.19 ? 381 MET A SD  1 
ATOM   2714 C CE  . MET A 1 353 ? 164.153 182.652 174.876 1.00 40.19 ? 381 MET A CE  1 
ATOM   2715 N N   . VAL A 1 354 ? 159.556 188.180 172.846 1.00 36.88 ? 382 VAL A N   1 
ATOM   2716 C CA  . VAL A 1 354 ? 158.605 188.813 171.942 1.00 36.88 ? 382 VAL A CA  1 
ATOM   2717 C C   . VAL A 1 354 ? 159.067 190.232 171.643 1.00 36.88 ? 382 VAL A C   1 
ATOM   2718 O O   . VAL A 1 354 ? 159.520 190.954 172.537 1.00 36.88 ? 382 VAL A O   1 
ATOM   2719 C CB  . VAL A 1 354 ? 157.174 188.814 172.521 1.00 36.88 ? 382 VAL A CB  1 
ATOM   2720 C CG1 . VAL A 1 354 ? 156.678 187.392 172.721 1.00 36.88 ? 382 VAL A CG1 1 
ATOM   2721 C CG2 . VAL A 1 354 ? 157.122 189.575 173.835 1.00 36.88 ? 382 VAL A CG2 1 
ATOM   2722 N N   . VAL A 1 355 ? 158.976 190.617 170.375 1.00 35.35 ? 383 VAL A N   1 
ATOM   2723 C CA  . VAL A 1 355 ? 159.243 191.977 169.930 1.00 35.35 ? 383 VAL A CA  1 
ATOM   2724 C C   . VAL A 1 355 ? 158.076 192.394 169.046 1.00 35.35 ? 383 VAL A C   1 
ATOM   2725 O O   . VAL A 1 355 ? 157.382 191.550 168.472 1.00 35.35 ? 383 VAL A O   1 
ATOM   2726 C CB  . VAL A 1 355 ? 160.588 192.082 169.177 1.00 35.35 ? 383 VAL A CB  1 
ATOM   2727 C CG1 . VAL A 1 355 ? 160.959 193.528 168.932 1.00 35.35 ? 383 VAL A CG1 1 
ATOM   2728 C CG2 . VAL A 1 355 ? 161.688 191.381 169.946 1.00 35.35 ? 383 VAL A CG2 1 
ATOM   2729 N N   . ASP A 1 356 ? 157.855 193.703 168.935 1.00 38.22 ? 384 ASP A N   1 
ATOM   2730 C CA  . ASP A 1 356 ? 156.649 194.199 168.282 1.00 38.22 ? 384 ASP A CA  1 
ATOM   2731 C C   . ASP A 1 356 ? 156.621 193.953 166.777 1.00 38.22 ? 384 ASP A C   1 
ATOM   2732 O O   . ASP A 1 356 ? 155.577 194.179 166.158 1.00 38.22 ? 384 ASP A O   1 
ATOM   2733 C CB  . ASP A 1 356 ? 156.482 195.693 168.559 1.00 38.22 ? 384 ASP A CB  1 
ATOM   2734 C CG  . ASP A 1 356 ? 155.099 196.200 168.203 1.00 38.22 ? 384 ASP A CG  1 
ATOM   2735 O OD1 . ASP A 1 356 ? 155.001 197.231 167.506 1.00 38.22 ? 384 ASP A OD1 1 
ATOM   2736 O OD2 . ASP A 1 356 ? 154.110 195.561 168.616 1.00 38.22 ? 384 ASP A OD2 1 
ATOM   2737 N N   . VAL A 1 357 ? 157.726 193.510 166.172 1.00 36.44 ? 385 VAL A N   1 
ATOM   2738 C CA  . VAL A 1 357 ? 157.740 193.290 164.730 1.00 36.44 ? 385 VAL A CA  1 
ATOM   2739 C C   . VAL A 1 357 ? 156.733 192.213 164.352 1.00 36.44 ? 385 VAL A C   1 
ATOM   2740 O O   . VAL A 1 357 ? 156.529 191.236 165.085 1.00 36.44 ? 385 VAL A O   1 
ATOM   2741 C CB  . VAL A 1 357 ? 159.154 192.919 164.258 1.00 36.44 ? 385 VAL A CB  1 
ATOM   2742 C CG1 . VAL A 1 357 ? 160.137 193.974 164.689 1.00 36.44 ? 385 VAL A CG1 1 
ATOM   2743 C CG2 . VAL A 1 357 ? 159.566 191.579 164.822 1.00 36.44 ? 385 VAL A CG2 1 
ATOM   2744 N N   . LYS A 1 358 ? 156.073 192.400 163.201 1.00 38.88 ? 386 LYS A N   1 
ATOM   2745 C CA  . LYS A 1 358 ? 155.109 191.427 162.673 1.00 38.88 ? 386 LYS A CA  1 
ATOM   2746 C C   . LYS A 1 358 ? 155.434 191.141 161.198 1.00 38.88 ? 386 LYS A C   1 
ATOM   2747 O O   . LYS A 1 358 ? 154.883 191.735 160.269 1.00 38.88 ? 386 LYS A O   1 
ATOM   2748 C CB  . LYS A 1 358 ? 153.647 191.915 162.905 1.00 38.88 ? 386 LYS A CB  1 
ATOM   2749 C CG  . LYS A 1 358 ? 153.173 193.110 162.084 1.00 38.88 ? 386 LYS A CG  1 
ATOM   2750 C CD  . LYS A 1 358 ? 151.894 193.703 162.639 1.00 38.88 ? 386 LYS A CD  1 
ATOM   2751 C CE  . LYS A 1 358 ? 151.278 194.676 161.649 1.00 38.88 ? 386 LYS A CE  1 
ATOM   2752 N NZ  . LYS A 1 358 ? 150.234 195.524 162.282 1.00 38.88 ? 386 LYS A NZ  1 
ATOM   2753 N N   . PHE A 1 359 ? 156.351 190.199 160.990 1.00 36.73 ? 387 PHE A N   1 
ATOM   2754 C CA  . PHE A 1 359 ? 156.702 189.707 159.665 1.00 36.73 ? 387 PHE A CA  1 
ATOM   2755 C C   . PHE A 1 359 ? 157.586 188.483 159.830 1.00 36.73 ? 387 PHE A C   1 
ATOM   2756 O O   . PHE A 1 359 ? 158.433 188.444 160.723 1.00 36.73 ? 387 PHE A O   1 
ATOM   2757 C CB  . PHE A 1 359 ? 157.405 190.783 158.823 1.00 36.73 ? 387 PHE A CB  1 
ATOM   2758 C CG  . PHE A 1 359 ? 158.726 191.237 159.375 1.00 36.73 ? 387 PHE A CG  1 
ATOM   2759 C CD1 . PHE A 1 359 ? 158.791 192.294 160.263 1.00 36.73 ? 387 PHE A CD1 1 
ATOM   2760 C CD2 . PHE A 1 359 ? 159.904 190.639 158.977 1.00 36.73 ? 387 PHE A CD2 1 
ATOM   2761 C CE1 . PHE A 1 359 ? 160.003 192.726 160.761 1.00 36.73 ? 387 PHE A CE1 1 
ATOM   2762 C CE2 . PHE A 1 359 ? 161.115 191.071 159.472 1.00 36.73 ? 387 PHE A CE2 1 
ATOM   2763 C CZ  . PHE A 1 359 ? 161.164 192.113 160.365 1.00 36.73 ? 387 PHE A CZ  1 
ATOM   2764 N N   . CYS A 1 360 ? 157.379 187.489 158.971 1.00 42.66 ? 388 CYS A N   1 
ATOM   2765 C CA  . CYS A 1 360 ? 158.046 186.194 159.079 1.00 42.66 ? 388 CYS A CA  1 
ATOM   2766 C C   . CYS A 1 360 ? 158.881 185.963 157.823 1.00 42.66 ? 388 CYS A C   1 
ATOM   2767 O O   . CYS A 1 360 ? 158.411 185.366 156.852 1.00 42.66 ? 388 CYS A O   1 
ATOM   2768 C CB  . CYS A 1 360 ? 157.024 185.080 159.280 1.00 42.66 ? 388 CYS A CB  1 
ATOM   2769 S SG  . CYS A 1 360 ? 156.033 185.241 160.782 1.00 42.66 ? 388 CYS A SG  1 
ATOM   2770 N N   . LEU A 1 361 ? 160.124 186.432 157.847 1.00 38.90 ? 389 LEU A N   1 
ATOM   2771 C CA  . LEU A 1 361 ? 161.059 186.207 156.746 1.00 38.90 ? 389 LEU A CA  1 
ATOM   2772 C C   . LEU A 1 361 ? 161.805 184.890 156.917 1.00 38.90 ? 389 LEU A C   1 
ATOM   2773 O O   . LEU A 1 361 ? 163.034 184.840 156.912 1.00 38.90 ? 389 LEU A O   1 
ATOM   2774 C CB  . LEU A 1 361 ? 162.030 187.374 156.635 1.00 38.90 ? 389 LEU A CB  1 
ATOM   2775 C CG  . LEU A 1 361 ? 161.689 188.442 155.599 1.00 38.90 ? 389 LEU A CG  1 
ATOM   2776 C CD1 . LEU A 1 361 ? 160.291 188.987 155.825 1.00 38.90 ? 389 LEU A CD1 1 
ATOM   2777 C CD2 . LEU A 1 361 ? 162.716 189.557 155.632 1.00 38.90 ? 389 LEU A CD2 1 
ATOM   2778 N N   . LYS A 1 362 ? 161.051 183.803 157.078 1.00 42.58 ? 390 LYS A N   1 
ATOM   2779 C CA  . LYS A 1 362 ? 161.670 182.495 157.252 1.00 42.58 ? 390 LYS A CA  1 
ATOM   2780 C C   . LYS A 1 362 ? 162.001 181.848 155.914 1.00 42.58 ? 390 LYS A C   1 
ATOM   2781 O O   . LYS A 1 362 ? 163.086 181.281 155.749 1.00 42.58 ? 390 LYS A O   1 
ATOM   2782 C CB  . LYS A 1 362 ? 160.754 181.586 158.070 1.00 42.58 ? 390 LYS A CB  1 
ATOM   2783 C CG  . LYS A 1 362 ? 161.412 180.296 158.519 1.00 42.58 ? 390 LYS A CG  1 
ATOM   2784 C CD  . LYS A 1 362 ? 160.396 179.336 159.105 1.00 42.58 ? 390 LYS A CD  1 
ATOM   2785 C CE  . LYS A 1 362 ? 161.041 178.008 159.451 1.00 42.58 ? 390 LYS A CE  1 
ATOM   2786 N NZ  . LYS A 1 362 ? 162.509 178.150 159.651 1.00 42.58 ? 390 LYS A NZ  1 
ATOM   2787 N N   . GLU A 1 363 ? 161.087 181.924 154.951 1.00 43.85 ? 391 GLU A N   1 
ATOM   2788 C CA  . GLU A 1 363 ? 161.285 181.314 153.637 1.00 43.85 ? 391 GLU A CA  1 
ATOM   2789 C C   . GLU A 1 363 ? 161.908 182.289 152.645 1.00 43.85 ? 391 GLU A C   1 
ATOM   2790 O O   . GLU A 1 363 ? 161.389 182.538 151.561 1.00 43.85 ? 391 GLU A O   1 
ATOM   2791 C CB  . GLU A 1 363 ? 159.962 180.768 153.119 1.00 43.85 ? 391 GLU A CB  1 
ATOM   2792 C CG  . GLU A 1 363 ? 159.443 179.599 153.928 1.00 43.85 ? 391 GLU A CG  1 
ATOM   2793 C CD  . GLU A 1 363 ? 158.710 180.036 155.174 1.00 43.85 ? 391 GLU A CD  1 
ATOM   2794 O OE1 . GLU A 1 363 ? 158.556 181.260 155.371 1.00 43.85 ? 391 GLU A OE1 1 
ATOM   2795 O OE2 . GLU A 1 363 ? 158.296 179.159 155.960 1.00 43.85 ? 391 GLU A OE2 1 
ATOM   2796 N N   . HIS A 1 364 ? 163.045 182.854 153.038 1.00 37.50 ? 392 HIS A N   1 
ATOM   2797 C CA  . HIS A 1 364 ? 163.874 183.651 152.152 1.00 37.50 ? 392 HIS A CA  1 
ATOM   2798 C C   . HIS A 1 364 ? 165.327 183.211 152.205 1.00 37.50 ? 392 HIS A C   1 
ATOM   2799 O O   . HIS A 1 364 ? 166.154 183.754 151.466 1.00 37.50 ? 392 HIS A O   1 
ATOM   2800 C CB  . HIS A 1 364 ? 163.774 185.140 152.511 1.00 37.50 ? 392 HIS A CB  1 
ATOM   2801 C CG  . HIS A 1 364 ? 162.508 185.791 152.052 1.00 37.50 ? 392 HIS A CG  1 
ATOM   2802 N ND1 . HIS A 1 364 ? 162.396 186.424 150.834 1.00 37.50 ? 392 HIS A ND1 1 
ATOM   2803 C CD2 . HIS A 1 364 ? 161.296 185.897 152.643 1.00 37.50 ? 392 HIS A CD2 1 
ATOM   2804 C CE1 . HIS A 1 364 ? 161.172 186.901 150.699 1.00 37.50 ? 392 HIS A CE1 1 
ATOM   2805 N NE2 . HIS A 1 364 ? 160.484 186.593 151.783 1.00 37.50 ? 392 HIS A NE2 1 
ATOM   2806 N N   . LYS A 1 365 ? 165.656 182.250 153.066 1.00 34.27 ? 393 LYS A N   1 
ATOM   2807 C CA  . LYS A 1 365 ? 167.015 181.751 153.208 1.00 34.27 ? 393 LYS A CA  1 
ATOM   2808 C C   . LYS A 1 365 ? 167.378 180.691 152.176 1.00 34.27 ? 393 LYS A C   1 
ATOM   2809 O O   . LYS A 1 365 ? 168.565 180.392 152.008 1.00 34.27 ? 393 LYS A O   1 
ATOM   2810 C CB  . LYS A 1 365 ? 167.198 181.202 154.627 1.00 34.27 ? 393 LYS A CB  1 
ATOM   2811 C CG  . LYS A 1 365 ? 166.220 180.087 154.995 1.00 34.27 ? 393 LYS A CG  1 
ATOM   2812 C CD  . LYS A 1 365 ? 166.749 178.694 154.692 1.00 34.27 ? 393 LYS A CD  1 
ATOM   2813 C CE  . LYS A 1 365 ? 165.769 177.627 155.153 1.00 34.27 ? 393 LYS A CE  1 
ATOM   2814 N NZ  . LYS A 1 365 ? 166.249 176.257 154.835 1.00 34.27 ? 393 LYS A NZ  1 
ATOM   2815 N N   . ALA A 1 366 ? 166.397 180.121 151.482 1.00 28.79 ? 394 ALA A N   1 
ATOM   2816 C CA  . ALA A 1 366 ? 166.625 179.037 150.534 1.00 28.79 ? 394 ALA A CA  1 
ATOM   2817 C C   . ALA A 1 366 ? 165.936 179.331 149.212 1.00 28.79 ? 394 ALA A C   1 
ATOM   2818 O O   . ALA A 1 366 ? 165.225 178.497 148.652 1.00 28.79 ? 394 ALA A O   1 
ATOM   2819 C CB  . ALA A 1 366 ? 166.148 177.707 151.105 1.00 28.79 ? 394 ALA A CB  1 
ATOM   2820 N N   . LEU A 1 367 ? 166.131 180.540 148.697 1.00 27.51 ? 395 LEU A N   1 
ATOM   2821 C CA  . LEU A 1 367 ? 165.570 180.933 147.411 1.00 27.51 ? 395 LEU A CA  1 
ATOM   2822 C C   . LEU A 1 367 ? 166.609 181.093 146.317 1.00 27.51 ? 395 LEU A C   1 
ATOM   2823 O O   . LEU A 1 367 ? 166.332 180.759 145.166 1.00 27.51 ? 395 LEU A O   1 
ATOM   2824 C CB  . LEU A 1 367 ? 164.791 182.243 147.543 1.00 27.51 ? 395 LEU A CB  1 
ATOM   2825 C CG  . LEU A 1 367 ? 163.341 182.122 147.995 1.00 27.51 ? 395 LEU A CG  1 
ATOM   2826 C CD1 . LEU A 1 367 ? 162.683 183.484 147.978 1.00 27.51 ? 395 LEU A CD1 1 
ATOM   2827 C CD2 . LEU A 1 367 ? 162.608 181.163 147.094 1.00 27.51 ? 395 LEU A CD2 1 
ATOM   2828 N N   . LYS A 1 368 ? 167.794 181.611 146.632 1.00 23.63 ? 396 LYS A N   1 
ATOM   2829 C CA  . LYS A 1 368 ? 168.781 181.821 145.582 1.00 23.63 ? 396 LYS A CA  1 
ATOM   2830 C C   . LYS A 1 368 ? 169.449 180.517 145.167 1.00 23.63 ? 396 LYS A C   1 
ATOM   2831 O O   . LYS A 1 368 ? 169.742 180.320 143.983 1.00 23.63 ? 396 LYS A O   1 
ATOM   2832 C CB  . LYS A 1 368 ? 169.826 182.838 146.032 1.00 23.63 ? 396 LYS A CB  1 
ATOM   2833 C CG  . LYS A 1 368 ? 170.649 183.418 144.889 1.00 23.63 ? 396 LYS A CG  1 
ATOM   2834 C CD  . LYS A 1 368 ? 169.837 183.521 143.602 1.00 23.63 ? 396 LYS A CD  1 
ATOM   2835 C CE  . LYS A 1 368 ? 170.379 184.601 142.678 1.00 23.63 ? 396 LYS A CE  1 
ATOM   2836 N NZ  . LYS A 1 368 ? 169.738 184.550 141.333 1.00 23.63 ? 396 LYS A NZ  1 
ATOM   2837 N N   . THR A 1 369 ? 169.699 179.615 146.118 1.00 23.72 ? 397 THR A N   1 
ATOM   2838 C CA  . THR A 1 369 ? 170.356 178.357 145.775 1.00 23.72 ? 397 THR A CA  1 
ATOM   2839 C C   . THR A 1 369 ? 169.465 177.485 144.894 1.00 23.72 ? 397 THR A C   1 
ATOM   2840 O O   . THR A 1 369 ? 169.941 176.879 143.925 1.00 23.72 ? 397 THR A O   1 
ATOM   2841 C CB  . THR A 1 369 ? 170.788 177.622 147.049 1.00 23.72 ? 397 THR A CB  1 
ATOM   2842 O OG1 . THR A 1 369 ? 171.546 176.460 146.703 1.00 23.72 ? 397 THR A OG1 1 
ATOM   2843 C CG2 . THR A 1 369 ? 169.599 177.212 147.899 1.00 23.72 ? 397 THR A CG2 1 
ATOM   2844 N N   . LEU A 1 370 ? 168.165 177.429 145.190 1.00 19.88 ? 398 LEU A N   1 
ATOM   2845 C CA  . LEU A 1 370 ? 167.265 176.647 144.352 1.00 19.88 ? 398 LEU A CA  1 
ATOM   2846 C C   . LEU A 1 370 ? 167.136 177.261 142.965 1.00 19.88 ? 398 LEU A C   1 
ATOM   2847 O O   . LEU A 1 370 ? 167.085 176.539 141.963 1.00 19.88 ? 398 LEU A O   1 
ATOM   2848 C CB  . LEU A 1 370 ? 165.902 176.520 145.024 1.00 19.88 ? 398 LEU A CB  1 
ATOM   2849 C CG  . LEU A 1 370 ? 165.903 175.592 146.237 1.00 19.88 ? 398 LEU A CG  1 
ATOM   2850 C CD1 . LEU A 1 370 ? 164.509 175.441 146.805 1.00 19.88 ? 398 LEU A CD1 1 
ATOM   2851 C CD2 . LEU A 1 370 ? 166.470 174.241 145.862 1.00 19.88 ? 398 LEU A CD2 1 
ATOM   2852 N N   . GLY A 1 371 ? 167.083 178.588 142.884 1.00 20.44 ? 399 GLY A N   1 
ATOM   2853 C CA  . GLY A 1 371 ? 167.071 179.231 141.583 1.00 20.44 ? 399 GLY A CA  1 
ATOM   2854 C C   . GLY A 1 371 ? 168.324 178.931 140.786 1.00 20.44 ? 399 GLY A C   1 
ATOM   2855 O O   . GLY A 1 371 ? 168.264 178.723 139.572 1.00 20.44 ? 399 GLY A O   1 
ATOM   2856 N N   . ILE A 1 372 ? 169.474 178.896 141.461 1.00 21.53 ? 400 ILE A N   1 
ATOM   2857 C CA  . ILE A 1 372 ? 170.719 178.533 140.792 1.00 21.53 ? 400 ILE A CA  1 
ATOM   2858 C C   . ILE A 1 372 ? 170.637 177.113 140.256 1.00 21.53 ? 400 ILE A C   1 
ATOM   2859 O O   . ILE A 1 372 ? 171.068 176.833 139.132 1.00 21.53 ? 400 ILE A O   1 
ATOM   2860 C CB  . ILE A 1 372 ? 171.912 178.704 141.750 1.00 21.53 ? 400 ILE A CB  1 
ATOM   2861 C CG1 . ILE A 1 372 ? 172.268 180.181 141.903 1.00 21.53 ? 400 ILE A CG1 1 
ATOM   2862 C CG2 . ILE A 1 372 ? 173.106 177.913 141.257 1.00 21.53 ? 400 ILE A CG2 1 
ATOM   2863 C CD1 . ILE A 1 372 ? 173.489 180.424 142.759 1.00 21.53 ? 400 ILE A CD1 1 
ATOM   2864 N N   . ILE A 1 373 ? 170.088 176.193 141.051 1.00 19.84 ? 401 ILE A N   1 
ATOM   2865 C CA  . ILE A 1 373 ? 169.957 174.807 140.602 1.00 19.84 ? 401 ILE A CA  1 
ATOM   2866 C C   . ILE A 1 373 ? 169.081 174.727 139.357 1.00 19.84 ? 401 ILE A C   1 
ATOM   2867 O O   . ILE A 1 373 ? 169.423 174.053 138.376 1.00 19.84 ? 401 ILE A O   1 
ATOM   2868 C CB  . ILE A 1 373 ? 169.404 173.927 141.734 1.00 19.84 ? 401 ILE A CB  1 
ATOM   2869 C CG1 . ILE A 1 373 ? 170.527 173.491 142.661 1.00 19.84 ? 401 ILE A CG1 1 
ATOM   2870 C CG2 . ILE A 1 373 ? 168.680 172.717 141.182 1.00 19.84 ? 401 ILE A CG2 1 
ATOM   2871 C CD1 . ILE A 1 373 ? 170.022 172.731 143.830 1.00 19.84 ? 401 ILE A CD1 1 
ATOM   2872 N N   . MET A 1 374 ? 167.935 175.408 139.380 1.00 21.01 ? 402 MET A N   1 
ATOM   2873 C CA  . MET A 1 374 ? 167.037 175.368 138.229 1.00 21.01 ? 402 MET A CA  1 
ATOM   2874 C C   . MET A 1 374 ? 167.697 175.961 136.991 1.00 21.01 ? 402 MET A C   1 
ATOM   2875 O O   . MET A 1 374 ? 167.611 175.390 135.894 1.00 21.01 ? 402 MET A O   1 
ATOM   2876 C CB  . MET A 1 374 ? 165.738 176.104 138.547 1.00 21.01 ? 402 MET A CB  1 
ATOM   2877 C CG  . MET A 1 374 ? 165.113 175.700 139.865 1.00 21.01 ? 402 MET A CG  1 
ATOM   2878 S SD  . MET A 1 374 ? 163.338 175.956 139.960 1.00 21.01 ? 402 MET A SD  1 
ATOM   2879 C CE  . MET A 1 374 ? 163.019 175.304 141.592 1.00 21.01 ? 402 MET A CE  1 
ATOM   2880 N N   . GLY A 1 375 ? 168.362 177.106 137.145 1.00 19.25 ? 403 GLY A N   1 
ATOM   2881 C CA  . GLY A 1 375 ? 169.021 177.721 136.007 1.00 19.25 ? 403 GLY A CA  1 
ATOM   2882 C C   . GLY A 1 375 ? 170.124 176.852 135.443 1.00 19.25 ? 403 GLY A C   1 
ATOM   2883 O O   . GLY A 1 375 ? 170.268 176.728 134.225 1.00 19.25 ? 403 GLY A O   1 
ATOM   2884 N N   . THR A 1 376 ? 170.911 176.230 136.320 1.00 21.90 ? 404 THR A N   1 
ATOM   2885 C CA  . THR A 1 376 ? 171.966 175.336 135.864 1.00 21.90 ? 404 THR A CA  1 
ATOM   2886 C C   . THR A 1 376 ? 171.395 174.146 135.108 1.00 21.90 ? 404 THR A C   1 
ATOM   2887 O O   . THR A 1 376 ? 171.910 173.775 134.047 1.00 21.90 ? 404 THR A O   1 
ATOM   2888 C CB  . THR A 1 376 ? 172.799 174.863 137.052 1.00 21.90 ? 404 THR A CB  1 
ATOM   2889 O OG1 . THR A 1 376 ? 173.417 175.991 137.680 1.00 21.90 ? 404 THR A OG1 1 
ATOM   2890 C CG2 . THR A 1 376 ? 173.861 173.898 136.598 1.00 21.90 ? 404 THR A CG2 1 
ATOM   2891 N N   . PHE A 1 377 ? 170.329 173.535 135.631 1.00 16.05 ? 405 PHE A N   1 
ATOM   2892 C CA  . PHE A 1 377 ? 169.755 172.380 134.949 1.00 16.05 ? 405 PHE A CA  1 
ATOM   2893 C C   . PHE A 1 377 ? 169.231 172.766 133.574 1.00 16.05 ? 405 PHE A C   1 
ATOM   2894 O O   . PHE A 1 377 ? 169.466 172.058 132.586 1.00 16.05 ? 405 PHE A O   1 
ATOM   2895 C CB  . PHE A 1 377 ? 168.640 171.755 135.783 1.00 16.05 ? 405 PHE A CB  1 
ATOM   2896 C CG  . PHE A 1 377 ? 168.157 170.442 135.242 1.00 16.05 ? 405 PHE A CG  1 
ATOM   2897 C CD1 . PHE A 1 377 ? 168.739 169.259 135.651 1.00 16.05 ? 405 PHE A CD1 1 
ATOM   2898 C CD2 . PHE A 1 377 ? 167.144 170.389 134.305 1.00 16.05 ? 405 PHE A CD2 1 
ATOM   2899 C CE1 . PHE A 1 377 ? 168.311 168.051 135.149 1.00 16.05 ? 405 PHE A CE1 1 
ATOM   2900 C CE2 . PHE A 1 377 ? 166.717 169.181 133.799 1.00 16.05 ? 405 PHE A CE2 1 
ATOM   2901 C CZ  . PHE A 1 377 ? 167.299 168.014 134.223 1.00 16.05 ? 405 PHE A CZ  1 
ATOM   2902 N N   . THR A 1 378 ? 168.513 173.888 133.487 1.00 19.01 ? 406 THR A N   1 
ATOM   2903 C CA  . THR A 1 378 ? 167.995 174.305 132.189 1.00 19.01 ? 406 THR A CA  1 
ATOM   2904 C C   . THR A 1 378 ? 169.129 174.616 131.220 1.00 19.01 ? 406 THR A C   1 
ATOM   2905 O O   . THR A 1 378 ? 169.105 174.172 130.067 1.00 19.01 ? 406 THR A O   1 
ATOM   2906 C CB  . THR A 1 378 ? 167.068 175.507 132.343 1.00 19.01 ? 406 THR A CB  1 
ATOM   2907 O OG1 . THR A 1 378 ? 165.872 175.099 133.014 1.00 19.01 ? 406 THR A OG1 1 
ATOM   2908 C CG2 . THR A 1 378 ? 166.698 176.065 130.986 1.00 19.01 ? 406 THR A CG2 1 
ATOM   2909 N N   . LEU A 1 379 ? 170.154 175.339 131.679 1.00 18.81 ? 407 LEU A N   1 
ATOM   2910 C CA  . LEU A 1 379 ? 171.265 175.679 130.797 1.00 18.81 ? 407 LEU A CA  1 
ATOM   2911 C C   . LEU A 1 379 ? 171.983 174.431 130.304 1.00 18.81 ? 407 LEU A C   1 
ATOM   2912 O O   . LEU A 1 379 ? 172.422 174.375 129.151 1.00 18.81 ? 407 LEU A O   1 
ATOM   2913 C CB  . LEU A 1 379 ? 172.245 176.606 131.513 1.00 18.81 ? 407 LEU A CB  1 
ATOM   2914 C CG  . LEU A 1 379 ? 171.827 178.064 131.705 1.00 18.81 ? 407 LEU A CG  1 
ATOM   2915 C CD1 . LEU A 1 379 ? 172.839 178.803 132.562 1.00 18.81 ? 407 LEU A CD1 1 
ATOM   2916 C CD2 . LEU A 1 379 ? 171.662 178.755 130.365 1.00 18.81 ? 407 LEU A CD2 1 
ATOM   2917 N N   . CYS A 1 380 ? 172.121 173.421 131.164 1.00 22.54 ? 408 CYS A N   1 
ATOM   2918 C CA  . CYS A 1 380 ? 172.847 172.220 130.772 1.00 22.54 ? 408 CYS A CA  1 
ATOM   2919 C C   . CYS A 1 380 ? 172.033 171.302 129.869 1.00 22.54 ? 408 CYS A C   1 
ATOM   2920 O O   . CYS A 1 380 ? 172.611 170.635 129.004 1.00 22.54 ? 408 CYS A O   1 
ATOM   2921 C CB  . CYS A 1 380 ? 173.310 171.452 132.010 1.00 22.54 ? 408 CYS A CB  1 
ATOM   2922 S SG  . CYS A 1 380 ? 174.707 172.210 132.861 1.00 22.54 ? 408 CYS A SG  1 
ATOM   2923 N N   . TRP A 1 381 ? 170.712 171.237 130.036 1.00 17.73 ? 409 TRP A N   1 
ATOM   2924 C CA  . TRP A 1 381 ? 169.955 170.238 129.292 1.00 17.73 ? 409 TRP A CA  1 
ATOM   2925 C C   . TRP A 1 381 ? 169.183 170.783 128.098 1.00 17.73 ? 409 TRP A C   1 
ATOM   2926 O O   . TRP A 1 381 ? 168.879 170.007 127.188 1.00 17.73 ? 409 TRP A O   1 
ATOM   2927 C CB  . TRP A 1 381 ? 168.986 169.500 130.220 1.00 17.73 ? 409 TRP A CB  1 
ATOM   2928 C CG  . TRP A 1 381 ? 169.579 168.247 130.787 1.00 17.73 ? 409 TRP A CG  1 
ATOM   2929 C CD1 . TRP A 1 381 ? 170.001 168.047 132.066 1.00 17.73 ? 409 TRP A CD1 1 
ATOM   2930 C CD2 . TRP A 1 381 ? 169.834 167.027 130.088 1.00 17.73 ? 409 TRP A CD2 1 
ATOM   2931 N NE1 . TRP A 1 381 ? 170.498 166.777 132.209 1.00 17.73 ? 409 TRP A NE1 1 
ATOM   2932 C CE2 . TRP A 1 381 ? 170.407 166.131 131.006 1.00 17.73 ? 409 TRP A CE2 1 
ATOM   2933 C CE3 . TRP A 1 381 ? 169.630 166.604 128.775 1.00 17.73 ? 409 TRP A CE3 1 
ATOM   2934 C CZ2 . TRP A 1 381 ? 170.776 164.842 130.655 1.00 17.73 ? 409 TRP A CZ2 1 
ATOM   2935 C CZ3 . TRP A 1 381 ? 169.997 165.323 128.430 1.00 17.73 ? 409 TRP A CZ3 1 
ATOM   2936 C CH2 . TRP A 1 381 ? 170.563 164.458 129.365 1.00 17.73 ? 409 TRP A CH2 1 
ATOM   2937 N N   . LEU A 1 382 ? 168.852 172.073 128.060 1.00 20.29 ? 410 LEU A N   1 
ATOM   2938 C CA  . LEU A 1 382 ? 168.097 172.596 126.923 1.00 20.29 ? 410 LEU A CA  1 
ATOM   2939 C C   . LEU A 1 382 ? 168.827 172.488 125.588 1.00 20.29 ? 410 LEU A C   1 
ATOM   2940 O O   . LEU A 1 382 ? 168.165 172.156 124.589 1.00 20.29 ? 410 LEU A O   1 
ATOM   2941 C CB  . LEU A 1 382 ? 167.686 174.048 127.189 1.00 20.29 ? 410 LEU A CB  1 
ATOM   2942 C CG  . LEU A 1 382 ? 166.642 174.607 126.223 1.00 20.29 ? 410 LEU A CG  1 
ATOM   2943 C CD1 . LEU A 1 382 ? 165.544 173.589 125.982 1.00 20.29 ? 410 LEU A CD1 1 
ATOM   2944 C CD2 . LEU A 1 382 ? 166.060 175.902 126.753 1.00 20.29 ? 410 LEU A CD2 1 
ATOM   2945 N N   . PRO A 1 383 ? 170.132 172.782 125.473 1.00 19.50 ? 411 PRO A N   1 
ATOM   2946 C CA  . PRO A 1 383 ? 170.778 172.661 124.156 1.00 19.50 ? 411 PRO A CA  1 
ATOM   2947 C C   . PRO A 1 383 ? 170.616 171.294 123.519 1.00 19.50 ? 411 PRO A C   1 
ATOM   2948 O O   . PRO A 1 383 ? 170.416 171.208 122.301 1.00 19.50 ? 411 PRO A O   1 
ATOM   2949 C CB  . PRO A 1 383 ? 172.249 172.967 124.464 1.00 19.50 ? 411 PRO A CB  1 
ATOM   2950 C CG  . PRO A 1 383 ? 172.205 173.844 125.636 1.00 19.50 ? 411 PRO A CG  1 
ATOM   2951 C CD  . PRO A 1 383 ? 171.047 173.373 126.465 1.00 19.50 ? 411 PRO A CD  1 
ATOM   2952 N N   . PHE A 1 384 ? 170.687 170.216 124.303 1.00 20.70 ? 412 PHE A N   1 
ATOM   2953 C CA  . PHE A 1 384 ? 170.514 168.897 123.710 1.00 20.70 ? 412 PHE A CA  1 
ATOM   2954 C C   . PHE A 1 384 ? 169.119 168.729 123.133 1.00 20.70 ? 412 PHE A C   1 
ATOM   2955 O O   . PHE A 1 384 ? 168.959 168.181 122.040 1.00 20.70 ? 412 PHE A O   1 
ATOM   2956 C CB  . PHE A 1 384 ? 170.792 167.788 124.718 1.00 20.70 ? 412 PHE A CB  1 
ATOM   2957 C CG  . PHE A 1 384 ? 170.272 166.457 124.272 1.00 20.70 ? 412 PHE A CG  1 
ATOM   2958 C CD1 . PHE A 1 384 ? 170.803 165.836 123.163 1.00 20.70 ? 412 PHE A CD1 1 
ATOM   2959 C CD2 . PHE A 1 384 ? 169.242 165.837 124.944 1.00 20.70 ? 412 PHE A CD2 1 
ATOM   2960 C CE1 . PHE A 1 384 ? 170.316 164.628 122.733 1.00 20.70 ? 412 PHE A CE1 1 
ATOM   2961 C CE2 . PHE A 1 384 ? 168.762 164.619 124.520 1.00 20.70 ? 412 PHE A CE2 1 
ATOM   2962 C CZ  . PHE A 1 384 ? 169.300 164.017 123.413 1.00 20.70 ? 412 PHE A CZ  1 
ATOM   2963 N N   . PHE A 1 385 ? 168.094 169.189 123.847 1.00 16.45 ? 413 PHE A N   1 
ATOM   2964 C CA  . PHE A 1 385 ? 166.745 169.022 123.323 1.00 16.45 ? 413 PHE A CA  1 
ATOM   2965 C C   . PHE A 1 385 ? 166.497 169.920 122.120 1.00 16.45 ? 413 PHE A C   1 
ATOM   2966 O O   . PHE A 1 385 ? 165.752 169.539 121.212 1.00 16.45 ? 413 PHE A O   1 
ATOM   2967 C CB  . PHE A 1 385 ? 165.714 169.275 124.418 1.00 16.45 ? 413 PHE A CB  1 
ATOM   2968 C CG  . PHE A 1 385 ? 165.427 168.068 125.261 1.00 16.45 ? 413 PHE A CG  1 
ATOM   2969 C CD1 . PHE A 1 385 ? 164.382 167.226 124.949 1.00 16.45 ? 413 PHE A CD1 1 
ATOM   2970 C CD2 . PHE A 1 385 ? 166.208 167.772 126.360 1.00 16.45 ? 413 PHE A CD2 1 
ATOM   2971 C CE1 . PHE A 1 385 ? 164.122 166.122 125.718 1.00 16.45 ? 413 PHE A CE1 1 
ATOM   2972 C CE2 . PHE A 1 385 ? 165.950 166.668 127.131 1.00 16.45 ? 413 PHE A CE2 1 
ATOM   2973 C CZ  . PHE A 1 385 ? 164.908 165.843 126.811 1.00 16.45 ? 413 PHE A CZ  1 
ATOM   2974 N N   . ILE A 1 386 ? 167.120 171.098 122.076 1.00 23.48 ? 414 ILE A N   1 
ATOM   2975 C CA  . ILE A 1 386 ? 166.955 171.948 120.901 1.00 23.48 ? 414 ILE A CA  1 
ATOM   2976 C C   . ILE A 1 386 ? 167.648 171.320 119.694 1.00 23.48 ? 414 ILE A C   1 
ATOM   2977 O O   . ILE A 1 386 ? 167.129 171.363 118.572 1.00 23.48 ? 414 ILE A O   1 
ATOM   2978 C CB  . ILE A 1 386 ? 167.441 173.384 121.189 1.00 23.48 ? 414 ILE A CB  1 
ATOM   2979 C CG1 . ILE A 1 386 ? 166.622 174.390 120.381 1.00 23.48 ? 414 ILE A CG1 1 
ATOM   2980 C CG2 . ILE A 1 386 ? 168.912 173.572 120.875 1.00 23.48 ? 414 ILE A CG2 1 
ATOM   2981 C CD1 . ILE A 1 386 ? 165.199 174.546 120.866 1.00 23.48 ? 414 ILE A CD1 1 
ATOM   2982 N N   . VAL A 1 387 ? 168.803 170.686 119.906 1.00 26.14 ? 415 VAL A N   1 
ATOM   2983 C CA  . VAL A 1 387 ? 169.448 169.972 118.810 1.00 26.14 ? 415 VAL A CA  1 
ATOM   2984 C C   . VAL A 1 387 ? 168.617 168.768 118.394 1.00 26.14 ? 415 VAL A C   1 
ATOM   2985 O O   . VAL A 1 387 ? 168.535 168.441 117.206 1.00 26.14 ? 415 VAL A O   1 
ATOM   2986 C CB  . VAL A 1 387 ? 170.881 169.579 119.206 1.00 26.14 ? 415 VAL A CB  1 
ATOM   2987 C CG1 . VAL A 1 387 ? 171.423 168.518 118.275 1.00 26.14 ? 415 VAL A CG1 1 
ATOM   2988 C CG2 . VAL A 1 387 ? 171.763 170.804 119.162 1.00 26.14 ? 415 VAL A CG2 1 
ATOM   2989 N N   . ASN A 1 388 ? 167.979 168.101 119.355 1.00 27.17 ? 416 ASN A N   1 
ATOM   2990 C CA  . ASN A 1 388 ? 167.097 166.986 119.033 1.00 27.17 ? 416 ASN A CA  1 
ATOM   2991 C C   . ASN A 1 388 ? 165.926 167.447 118.178 1.00 27.17 ? 416 ASN A C   1 
ATOM   2992 O O   . ASN A 1 388 ? 165.532 166.762 117.227 1.00 27.17 ? 416 ASN A O   1 
ATOM   2993 C CB  . ASN A 1 388 ? 166.600 166.336 120.324 1.00 27.17 ? 416 ASN A CB  1 
ATOM   2994 C CG  . ASN A 1 388 ? 166.039 164.953 120.102 1.00 27.17 ? 416 ASN A CG  1 
ATOM   2995 O OD1 . ASN A 1 388 ? 166.047 164.443 118.986 1.00 27.17 ? 416 ASN A OD1 1 
ATOM   2996 N ND2 . ASN A 1 388 ? 165.551 164.334 121.169 1.00 27.17 ? 416 ASN A ND2 1 
ATOM   2997 N N   . ILE A 1 389 ? 165.360 168.611 118.498 1.00 31.88 ? 417 ILE A N   1 
ATOM   2998 C CA  . ILE A 1 389 ? 164.231 169.118 117.729 1.00 31.88 ? 417 ILE A CA  1 
ATOM   2999 C C   . ILE A 1 389 ? 164.668 169.660 116.373 1.00 31.88 ? 417 ILE A C   1 
ATOM   3000 O O   . ILE A 1 389 ? 163.848 169.733 115.452 1.00 31.88 ? 417 ILE A O   1 
ATOM   3001 C CB  . ILE A 1 389 ? 163.467 170.190 118.524 1.00 31.88 ? 417 ILE A CB  1 
ATOM   3002 C CG1 . ILE A 1 389 ? 161.982 170.155 118.170 1.00 31.88 ? 417 ILE A CG1 1 
ATOM   3003 C CG2 . ILE A 1 389 ? 164.020 171.576 118.250 1.00 31.88 ? 417 ILE A CG2 1 
ATOM   3004 C CD1 . ILE A 1 389 ? 161.277 168.924 118.679 1.00 31.88 ? 417 ILE A CD1 1 
ATOM   3005 N N   . VAL A 1 390 ? 165.931 170.066 116.230 1.00 38.51 ? 418 VAL A N   1 
ATOM   3006 C CA  . VAL A 1 390 ? 166.457 170.373 114.902 1.00 38.51 ? 418 VAL A CA  1 
ATOM   3007 C C   . VAL A 1 390 ? 166.646 169.094 114.092 1.00 38.51 ? 418 VAL A C   1 
ATOM   3008 O O   . VAL A 1 390 ? 166.379 169.060 112.885 1.00 38.51 ? 418 VAL A O   1 
ATOM   3009 C CB  . VAL A 1 390 ? 167.767 171.174 115.009 1.00 38.51 ? 418 VAL A CB  1 
ATOM   3010 C CG1 . VAL A 1 390 ? 168.365 171.393 113.634 1.00 38.51 ? 418 VAL A CG1 1 
ATOM   3011 C CG2 . VAL A 1 390 ? 167.510 172.511 115.667 1.00 38.51 ? 418 VAL A CG2 1 
ATOM   3012 N N   . HIS A 1 391 ? 167.102 168.025 114.743 1.00 45.67 ? 419 HIS A N   1 
ATOM   3013 C CA  . HIS A 1 391 ? 167.465 166.788 114.065 1.00 45.67 ? 419 HIS A CA  1 
ATOM   3014 C C   . HIS A 1 391 ? 166.269 165.899 113.747 1.00 45.67 ? 419 HIS A C   1 
ATOM   3015 O O   . HIS A 1 391 ? 166.439 164.891 113.052 1.00 45.67 ? 419 HIS A O   1 
ATOM   3016 C CB  . HIS A 1 391 ? 168.475 166.021 114.924 1.00 45.67 ? 419 HIS A CB  1 
ATOM   3017 C CG  . HIS A 1 391 ? 169.042 164.805 114.261 1.00 45.67 ? 419 HIS A CG  1 
ATOM   3018 N ND1 . HIS A 1 391 ? 168.428 163.573 114.319 1.00 45.67 ? 419 HIS A ND1 1 
ATOM   3019 C CD2 . HIS A 1 391 ? 170.167 164.631 113.528 1.00 45.67 ? 419 HIS A CD2 1 
ATOM   3020 C CE1 . HIS A 1 391 ? 169.151 162.692 113.651 1.00 45.67 ? 419 HIS A CE1 1 
ATOM   3021 N NE2 . HIS A 1 391 ? 170.211 163.309 113.160 1.00 45.67 ? 419 HIS A NE2 1 
ATOM   3022 N N   . VAL A 1 392 ? 165.120 166.269 114.274 1.00 48.54 ? 420 VAL A N   1 
ATOM   3023 C CA  . VAL A 1 392 ? 163.904 165.465 114.024 1.00 48.54 ? 420 VAL A CA  1 
ATOM   3024 C C   . VAL A 1 392 ? 163.827 165.401 112.526 1.00 48.54 ? 420 VAL A C   1 
ATOM   3025 O O   . VAL A 1 392 ? 163.949 164.326 111.952 1.00 48.54 ? 420 VAL A O   1 
ATOM   3026 C CB  . VAL A 1 392 ? 162.669 166.206 114.560 1.00 48.54 ? 420 VAL A CB  1 
ATOM   3027 N N   . ILE A 1 393 ? 163.702 166.580 111.955 1.00 56.95 ? 421 ILE A N   1 
ATOM   3028 C CA  . ILE A 1 393 ? 163.598 166.621 110.486 1.00 56.95 ? 421 ILE A CA  1 
ATOM   3029 C C   . ILE A 1 393 ? 164.893 165.982 109.997 1.00 56.95 ? 421 ILE A C   1 
ATOM   3030 O O   . ILE A 1 393 ? 165.916 166.184 110.648 1.00 56.95 ? 421 ILE A O   1 
ATOM   3031 C CB  . ILE A 1 393 ? 163.363 168.060 109.994 1.00 56.95 ? 421 ILE A CB  1 
ATOM   3032 C CG1 . ILE A 1 393 ? 163.148 168.111 108.479 1.00 56.95 ? 421 ILE A CG1 1 
ATOM   3033 C CG2 . ILE A 1 393 ? 164.455 169.010 110.448 1.00 56.95 ? 421 ILE A CG2 1 
ATOM   3034 C CD1 . ILE A 1 393 ? 161.961 167.305 108.001 1.00 56.95 ? 421 ILE A CD1 1 
ATOM   3035 N N   . GLN A 1 394 ? 164.863 165.256 108.879 1.00 60.95 ? 422 GLN A N   1 
ATOM   3036 C CA  . GLN A 1 394 ? 166.046 164.513 108.370 1.00 60.95 ? 422 GLN A CA  1 
ATOM   3037 C C   . GLN A 1 394 ? 166.952 165.555 107.740 1.00 60.95 ? 422 GLN A C   1 
ATOM   3038 O O   . GLN A 1 394 ? 167.921 165.180 107.073 1.00 60.95 ? 422 GLN A O   1 
ATOM   3039 C CB  . GLN A 1 394 ? 165.643 163.440 107.358 1.00 60.95 ? 422 GLN A CB  1 
ATOM   3040 N N   . ASP A 1 395 ? 166.614 166.824 107.945 1.00 63.88 ? 423 ASP A N   1 
ATOM   3041 C CA  . ASP A 1 395 ? 167.513 167.878 107.451 1.00 63.88 ? 423 ASP A CA  1 
ATOM   3042 C C   . ASP A 1 395 ? 168.852 167.521 108.077 1.00 63.88 ? 423 ASP A C   1 
ATOM   3043 O O   . ASP A 1 395 ? 169.856 167.584 107.354 1.00 63.88 ? 423 ASP A O   1 
ATOM   3044 C CB  . ASP A 1 395 ? 167.032 169.248 107.923 1.00 63.88 ? 423 ASP A CB  1 
ATOM   3045 N N   . ASN A 1 396 ? 168.856 167.129 109.352 1.00 66.34 ? 424 ASN A N   1 
ATOM   3046 C CA  . ASN A 1 396 ? 170.113 166.647 109.973 1.00 66.34 ? 424 ASN A CA  1 
ATOM   3047 C C   . ASN A 1 396 ? 171.206 167.621 109.560 1.00 66.34 ? 424 ASN A C   1 
ATOM   3048 O O   . ASN A 1 396 ? 172.161 167.181 108.903 1.00 66.34 ? 424 ASN A O   1 
ATOM   3049 C CB  . ASN A 1 396 ? 170.384 165.174 109.670 1.00 66.34 ? 424 ASN A CB  1 
ATOM   3050 N N   . LEU A 1 397 ? 171.073 168.888 109.944 1.00 61.46 ? 425 LEU A N   1 
ATOM   3051 C CA  . LEU A 1 397 ? 172.029 169.894 109.431 1.00 61.46 ? 425 LEU A CA  1 
ATOM   3052 C C   . LEU A 1 397 ? 173.456 169.420 109.725 1.00 61.46 ? 425 LEU A C   1 
ATOM   3053 O O   . LEU A 1 397 ? 174.277 169.483 108.794 1.00 61.46 ? 425 LEU A O   1 
ATOM   3054 C CB  . LEU A 1 397 ? 171.722 171.220 110.127 1.00 61.46 ? 425 LEU A CB  1 
ATOM   3055 N N   . ILE A 1 398 ? 173.763 168.968 110.938 1.00 61.06 ? 426 ILE A N   1 
ATOM   3056 C CA  . ILE A 1 398 ? 175.086 168.336 111.204 1.00 61.06 ? 426 ILE A CA  1 
ATOM   3057 C C   . ILE A 1 398 ? 174.823 167.418 112.379 1.00 61.06 ? 426 ILE A C   1 
ATOM   3058 O O   . ILE A 1 398 ? 174.234 167.908 113.359 1.00 61.06 ? 426 ILE A O   1 
ATOM   3059 C CB  . ILE A 1 398 ? 176.152 169.385 111.536 1.00 61.06 ? 426 ILE A CB  1 
ATOM   3060 N N   . ARG A 1 399 ? 175.222 166.154 112.298 1.00 57.49 ? 427 ARG A N   1 
ATOM   3061 C CA  . ARG A 1 399 ? 174.836 165.284 113.433 1.00 57.49 ? 427 ARG A CA  1 
ATOM   3062 C C   . ARG A 1 399 ? 175.669 164.027 113.555 1.00 57.49 ? 427 ARG A C   1 
ATOM   3063 O O   . ARG A 1 399 ? 176.486 163.816 112.657 1.00 57.49 ? 427 ARG A O   1 
ATOM   3064 C CB  . ARG A 1 399 ? 173.377 164.855 113.331 1.00 57.49 ? 427 ARG A CB  1 
ATOM   3065 N N   . LYS A 1 400 ? 175.526 163.342 114.684 1.00 53.59 ? 428 LYS A N   1 
ATOM   3066 C CA  . LYS A 1 400 ? 176.156 162.033 114.915 1.00 53.59 ? 428 LYS A CA  1 
ATOM   3067 C C   . LYS A 1 400 ? 177.498 162.216 115.585 1.00 53.59 ? 428 LYS A C   1 
ATOM   3068 O O   . LYS A 1 400 ? 178.006 161.255 116.168 1.00 53.59 ? 428 LYS A O   1 
ATOM   3069 C CB  . LYS A 1 400 ? 176.254 161.237 113.618 1.00 53.59 ? 428 LYS A CB  1 
ATOM   3070 N N   . GLU A 1 401 ? 178.004 163.425 115.569 1.00 55.23 ? 429 GLU A N   1 
ATOM   3071 C CA  . GLU A 1 401 ? 179.258 163.619 116.315 1.00 55.23 ? 429 GLU A CA  1 
ATOM   3072 C C   . GLU A 1 401 ? 179.132 164.956 117.035 1.00 55.23 ? 429 GLU A C   1 
ATOM   3073 O O   . GLU A 1 401 ? 180.153 165.435 117.556 1.00 55.23 ? 429 GLU A O   1 
ATOM   3074 C CB  . GLU A 1 401 ? 180.480 163.398 115.432 1.00 55.23 ? 429 GLU A CB  1 
ATOM   3075 N N   . VAL A 1 402 ? 177.933 165.539 117.039 1.00 42.61 ? 430 VAL A N   1 
ATOM   3076 C CA  . VAL A 1 402 ? 177.718 166.745 117.866 1.00 42.61 ? 430 VAL A CA  1 
ATOM   3077 C C   . VAL A 1 402 ? 176.704 166.253 118.848 1.00 42.61 ? 430 VAL A C   1 
ATOM   3078 O O   . VAL A 1 402 ? 176.765 166.603 120.018 1.00 42.61 ? 430 VAL A O   1 
ATOM   3079 C CB  . VAL A 1 402 ? 177.108 167.869 117.024 1.00 42.61 ? 430 VAL A CB  1 
ATOM   3080 C CG1 . VAL A 1 402 ? 175.806 167.487 116.350 1.00 42.61 ? 430 VAL A CG1 1 
ATOM   3081 C CG2 . VAL A 1 402 ? 176.950 169.157 117.805 1.00 42.61 ? 430 VAL A CG2 1 
ATOM   3082 N N   . TYR A 1 403 ? 175.965 165.273 118.416 1.00 37.03 ? 431 TYR A N   1 
ATOM   3083 C CA  . TYR A 1 403 ? 174.806 164.853 119.188 1.00 37.03 ? 431 TYR A CA  1 
ATOM   3084 C C   . TYR A 1 403 ? 175.193 164.110 120.458 1.00 37.03 ? 431 TYR A C   1 
ATOM   3085 O O   . TYR A 1 403 ? 174.406 164.082 121.407 1.00 37.03 ? 431 TYR A O   1 
ATOM   3086 C CB  . TYR A 1 403 ? 173.916 163.970 118.319 1.00 37.03 ? 431 TYR A CB  1 
ATOM   3087 C CG  . TYR A 1 403 ? 172.537 163.730 118.866 1.00 37.03 ? 431 TYR A CG  1 
ATOM   3088 C CD1 . TYR A 1 403 ? 172.170 162.483 119.348 1.00 37.03 ? 431 TYR A CD1 1 
ATOM   3089 C CD2 . TYR A 1 403 ? 171.589 164.739 118.867 1.00 37.03 ? 431 TYR A CD2 1 
ATOM   3090 C CE1 . TYR A 1 403 ? 170.900 162.252 119.837 1.00 37.03 ? 431 TYR A CE1 1 
ATOM   3091 C CE2 . TYR A 1 403 ? 170.317 164.519 119.350 1.00 37.03 ? 431 TYR A CE2 1 
ATOM   3092 C CZ  . TYR A 1 403 ? 169.977 163.273 119.834 1.00 37.03 ? 431 TYR A CZ  1 
ATOM   3093 O OH  . TYR A 1 403 ? 168.709 163.052 120.322 1.00 37.03 ? 431 TYR A OH  1 
ATOM   3094 N N   . ILE A 1 404 ? 176.379 163.509 120.497 1.00 38.37 ? 432 ILE A N   1 
ATOM   3095 C CA  . ILE A 1 404 ? 176.809 162.775 121.680 1.00 38.37 ? 432 ILE A CA  1 
ATOM   3096 C C   . ILE A 1 404 ? 177.490 163.691 122.691 1.00 38.37 ? 432 ILE A C   1 
ATOM   3097 O O   . ILE A 1 404 ? 177.324 163.509 123.904 1.00 38.37 ? 432 ILE A O   1 
ATOM   3098 C CB  . ILE A 1 404 ? 177.735 161.617 121.274 1.00 38.37 ? 432 ILE A CB  1 
ATOM   3099 C CG1 . ILE A 1 404 ? 177.068 160.760 120.200 1.00 38.37 ? 432 ILE A CG1 1 
ATOM   3100 C CG2 . ILE A 1 404 ? 178.087 160.766 122.479 1.00 38.37 ? 432 ILE A CG2 1 
ATOM   3101 C CD1 . ILE A 1 404 ? 178.019 159.825 119.487 1.00 38.37 ? 432 ILE A CD1 1 
ATOM   3102 N N   . LEU A 1 405 ? 178.255 164.675 122.221 1.00 36.12 ? 433 LEU A N   1 
ATOM   3103 C CA  . LEU A 1 405 ? 178.873 165.619 123.141 1.00 36.12 ? 433 LEU A CA  1 
ATOM   3104 C C   . LEU A 1 405 ? 177.824 166.384 123.936 1.00 36.12 ? 433 LEU A C   1 
ATOM   3105 O O   . LEU A 1 405 ? 178.052 166.715 125.104 1.00 36.12 ? 433 LEU A O   1 
ATOM   3106 C CB  . LEU A 1 405 ? 179.777 166.581 122.376 1.00 36.12 ? 433 LEU A CB  1 
ATOM   3107 C CG  . LEU A 1 405 ? 180.613 167.524 123.239 1.00 36.12 ? 433 LEU A CG  1 
ATOM   3108 C CD1 . LEU A 1 405 ? 181.537 166.722 124.136 1.00 36.12 ? 433 LEU A CD1 1 
ATOM   3109 C CD2 . LEU A 1 405 ? 181.405 168.480 122.366 1.00 36.12 ? 433 LEU A CD2 1 
ATOM   3110 N N   . LEU A 1 406 ? 176.662 166.650 123.336 1.00 30.82 ? 434 LEU A N   1 
ATOM   3111 C CA  . LEU A 1 406 ? 175.611 167.350 124.065 1.00 30.82 ? 434 LEU A CA  1 
ATOM   3112 C C   . LEU A 1 406 ? 174.931 166.442 125.084 1.00 30.82 ? 434 LEU A C   1 
ATOM   3113 O O   . LEU A 1 406 ? 174.588 166.896 126.183 1.00 30.82 ? 434 LEU A O   1 
ATOM   3114 C CB  . LEU A 1 406 ? 174.599 167.934 123.085 1.00 30.82 ? 434 LEU A CB  1 
ATOM   3115 C CG  . LEU A 1 406 ? 175.195 168.881 122.041 1.00 30.82 ? 434 LEU A CG  1 
ATOM   3116 C CD1 . LEU A 1 406 ? 174.107 169.724 121.430 1.00 30.82 ? 434 LEU A CD1 1 
ATOM   3117 C CD2 . LEU A 1 406 ? 176.281 169.768 122.632 1.00 30.82 ? 434 LEU A CD2 1 
ATOM   3118 N N   . ASN A 1 407 ? 174.830 165.155 124.749 1.00 30.63 ? 435 ASN A N   1 
ATOM   3119 C CA  . ASN A 1 407 ? 174.292 164.194 125.745 1.00 30.63 ? 435 ASN A CA  1 
ATOM   3120 C C   . ASN A 1 407 ? 175.290 164.113 126.911 1.00 30.63 ? 435 ASN A C   1 
ATOM   3121 O O   . ASN A 1 407 ? 174.828 163.905 128.046 1.00 30.63 ? 435 ASN A O   1 
ATOM   3122 C CB  . ASN A 1 407 ? 173.970 162.833 125.124 1.00 30.63 ? 435 ASN A CB  1 
ATOM   3123 C CG  . ASN A 1 407 ? 172.494 162.505 125.185 1.00 30.63 ? 435 ASN A CG  1 
ATOM   3124 O OD1 . ASN A 1 407 ? 171.775 163.012 126.044 1.00 30.63 ? 435 ASN A OD1 1 
ATOM   3125 N ND2 . ASN A 1 407 ? 172.031 161.662 124.276 1.00 30.63 ? 435 ASN A ND2 1 
ATOM   3126 N N   . TRP A 1 408 ? 176.593 164.307 126.647 1.00 28.30 ? 436 TRP A N   1 
ATOM   3127 C CA  . TRP A 1 408 ? 177.562 164.236 127.733 1.00 28.30 ? 436 TRP A CA  1 
ATOM   3128 C C   . TRP A 1 408 ? 177.584 165.519 128.556 1.00 28.30 ? 436 TRP A C   1 
ATOM   3129 O O   . TRP A 1 408 ? 177.773 165.466 129.778 1.00 28.30 ? 436 TRP A O   1 
ATOM   3130 C CB  . TRP A 1 408 ? 178.934 163.895 127.169 1.00 28.30 ? 436 TRP A CB  1 
ATOM   3131 C CG  . TRP A 1 408 ? 179.110 162.423 127.103 1.00 28.30 ? 436 TRP A CG  1 
ATOM   3132 C CD1 . TRP A 1 408 ? 179.053 161.639 125.994 1.00 28.30 ? 436 TRP A CD1 1 
ATOM   3133 C CD2 . TRP A 1 408 ? 179.336 161.547 128.205 1.00 28.30 ? 436 TRP A CD2 1 
ATOM   3134 N NE1 . TRP A 1 408 ? 179.242 160.325 126.335 1.00 28.30 ? 436 TRP A NE1 1 
ATOM   3135 C CE2 . TRP A 1 408 ? 179.419 160.243 127.691 1.00 28.30 ? 436 TRP A CE2 1 
ATOM   3136 C CE3 . TRP A 1 408 ? 179.484 161.740 129.579 1.00 28.30 ? 436 TRP A CE3 1 
ATOM   3137 C CZ2 . TRP A 1 408 ? 179.646 159.137 128.500 1.00 28.30 ? 436 TRP A CZ2 1 
ATOM   3138 C CZ3 . TRP A 1 408 ? 179.709 160.646 130.379 1.00 28.30 ? 436 TRP A CZ3 1 
ATOM   3139 C CH2 . TRP A 1 408 ? 179.788 159.359 129.841 1.00 28.30 ? 436 TRP A CH2 1 
ATOM   3140 N N   . ILE A 1 409 ? 177.374 166.669 127.916 1.00 31.30 ? 437 ILE A N   1 
ATOM   3141 C CA  . ILE A 1 409 ? 177.176 167.904 128.672 1.00 31.30 ? 437 ILE A CA  1 
ATOM   3142 C C   . ILE A 1 409 ? 175.955 167.778 129.573 1.00 31.30 ? 437 ILE A C   1 
ATOM   3143 O O   . ILE A 1 409 ? 175.954 168.255 130.714 1.00 31.30 ? 437 ILE A O   1 
ATOM   3144 C CB  . ILE A 1 409 ? 177.057 169.113 127.724 1.00 31.30 ? 437 ILE A CB  1 
ATOM   3145 C CG1 . ILE A 1 409 ? 178.352 169.315 126.939 1.00 31.30 ? 437 ILE A CG1 1 
ATOM   3146 C CG2 . ILE A 1 409 ? 176.721 170.369 128.501 1.00 31.30 ? 437 ILE A CG2 1 
ATOM   3147 C CD1 . ILE A 1 409 ? 178.228 170.313 125.811 1.00 31.30 ? 437 ILE A CD1 1 
ATOM   3148 N N   . GLY A 1 410 ? 174.897 167.137 129.078 1.00 29.40 ? 438 GLY A N   1 
ATOM   3149 C CA  . GLY A 1 410 ? 173.736 166.892 129.920 1.00 29.40 ? 438 GLY A CA  1 
ATOM   3150 C C   . GLY A 1 410 ? 174.035 165.957 131.077 1.00 29.40 ? 438 GLY A C   1 
ATOM   3151 O O   . GLY A 1 410 ? 173.563 166.169 132.196 1.00 29.40 ? 438 GLY A O   1 
ATOM   3152 N N   . TYR A 1 411 ? 174.812 164.905 130.819 1.00 27.19 ? 439 TYR A N   1 
ATOM   3153 C CA  . TYR A 1 411 ? 175.158 163.952 131.868 1.00 27.19 ? 439 TYR A CA  1 
ATOM   3154 C C   . TYR A 1 411 ? 175.956 164.620 132.977 1.00 27.19 ? 439 TYR A C   1 
ATOM   3155 O O   . TYR A 1 411 ? 175.692 164.406 134.165 1.00 27.19 ? 439 TYR A O   1 
ATOM   3156 C CB  . TYR A 1 411 ? 175.968 162.795 131.286 1.00 27.19 ? 439 TYR A CB  1 
ATOM   3157 C CG  . TYR A 1 411 ? 175.185 161.711 130.586 1.00 27.19 ? 439 TYR A CG  1 
ATOM   3158 C CD1 . TYR A 1 411 ? 175.699 161.089 129.462 1.00 27.19 ? 439 TYR A CD1 1 
ATOM   3159 C CD2 . TYR A 1 411 ? 173.955 161.292 131.055 1.00 27.19 ? 439 TYR A CD2 1 
ATOM   3160 C CE1 . TYR A 1 411 ? 175.012 160.094 128.817 1.00 27.19 ? 439 TYR A CE1 1 
ATOM   3161 C CE2 . TYR A 1 411 ? 173.258 160.293 130.411 1.00 27.19 ? 439 TYR A CE2 1 
ATOM   3162 C CZ  . TYR A 1 411 ? 173.797 159.700 129.293 1.00 27.19 ? 439 TYR A CZ  1 
ATOM   3163 O OH  . TYR A 1 411 ? 173.121 158.704 128.638 1.00 27.19 ? 439 TYR A OH  1 
ATOM   3164 N N   . VAL A 1 412 ? 176.943 165.438 132.605 1.00 29.60 ? 440 VAL A N   1 
ATOM   3165 C CA  . VAL A 1 412 ? 177.949 165.869 133.570 1.00 29.60 ? 440 VAL A CA  1 
ATOM   3166 C C   . VAL A 1 412 ? 177.378 166.805 134.628 1.00 29.60 ? 440 VAL A C   1 
ATOM   3167 O O   . VAL A 1 412 ? 177.991 166.979 135.687 1.00 29.60 ? 440 VAL A O   1 
ATOM   3168 C CB  . VAL A 1 412 ? 179.135 166.531 132.838 1.00 29.60 ? 440 VAL A CB  1 
ATOM   3169 C CG1 . VAL A 1 412 ? 178.707 167.830 132.181 1.00 29.60 ? 440 VAL A CG1 1 
ATOM   3170 C CG2 . VAL A 1 412 ? 180.313 166.745 133.774 1.00 29.60 ? 440 VAL A CG2 1 
ATOM   3171 N N   . ASN A 1 413 ? 176.207 167.399 134.393 1.00 29.60 ? 441 ASN A N   1 
ATOM   3172 C CA  . ASN A 1 413 ? 175.719 168.422 135.312 1.00 29.60 ? 441 ASN A CA  1 
ATOM   3173 C C   . ASN A 1 413 ? 175.302 167.866 136.666 1.00 29.60 ? 441 ASN A C   1 
ATOM   3174 O O   . ASN A 1 413 ? 175.074 168.653 137.588 1.00 29.60 ? 441 ASN A O   1 
ATOM   3175 C CB  . ASN A 1 413 ? 174.547 169.187 134.697 1.00 29.60 ? 441 ASN A CB  1 
ATOM   3176 C CG  . ASN A 1 413 ? 173.224 168.483 134.886 1.00 29.60 ? 441 ASN A CG  1 
ATOM   3177 O OD1 . ASN A 1 413 ? 173.150 167.257 134.887 1.00 29.60 ? 441 ASN A OD1 1 
ATOM   3178 N ND2 . ASN A 1 413 ? 172.168 169.262 135.068 1.00 29.60 ? 441 ASN A ND2 1 
ATOM   3179 N N   . SER A 1 414 ? 175.197 166.545 136.813 1.00 30.16 ? 442 SER A N   1 
ATOM   3180 C CA  . SER A 1 414 ? 174.753 165.980 138.081 1.00 30.16 ? 442 SER A CA  1 
ATOM   3181 C C   . SER A 1 414 ? 175.730 166.247 139.216 1.00 30.16 ? 442 SER A C   1 
ATOM   3182 O O   . SER A 1 414 ? 175.349 166.133 140.385 1.00 30.16 ? 442 SER A O   1 
ATOM   3183 C CB  . SER A 1 414 ? 174.525 164.482 137.938 1.00 30.16 ? 442 SER A CB  1 
ATOM   3184 O OG  . SER A 1 414 ? 173.272 164.240 137.337 1.00 30.16 ? 442 SER A OG  1 
ATOM   3185 N N   . GLY A 1 415 ? 176.976 166.584 138.906 1.00 31.72 ? 443 GLY A N   1 
ATOM   3186 C CA  . GLY A 1 415 ? 177.913 166.968 139.938 1.00 31.72 ? 443 GLY A CA  1 
ATOM   3187 C C   . GLY A 1 415 ? 177.825 168.408 140.367 1.00 31.72 ? 443 GLY A C   1 
ATOM   3188 O O   . GLY A 1 415 ? 178.490 168.802 141.327 1.00 31.72 ? 443 GLY A O   1 
ATOM   3189 N N   . PHE A 1 416 ? 177.014 169.212 139.678 1.00 30.59 ? 444 PHE A N   1 
ATOM   3190 C CA  . PHE A 1 416 ? 176.924 170.631 139.997 1.00 30.59 ? 444 PHE A CA  1 
ATOM   3191 C C   . PHE A 1 416 ? 176.108 170.883 141.258 1.00 30.59 ? 444 PHE A C   1 
ATOM   3192 O O   . PHE A 1 416 ? 176.343 171.876 141.952 1.00 30.59 ? 444 PHE A O   1 
ATOM   3193 C CB  . PHE A 1 416 ? 176.320 171.408 138.823 1.00 30.59 ? 444 PHE A CB  1 
ATOM   3194 C CG  . PHE A 1 416 ? 177.187 171.439 137.584 1.00 30.59 ? 444 PHE A CG  1 
ATOM   3195 C CD1 . PHE A 1 416 ? 178.314 170.644 137.470 1.00 30.59 ? 444 PHE A CD1 1 
ATOM   3196 C CD2 . PHE A 1 416 ? 176.859 172.269 136.526 1.00 30.59 ? 444 PHE A CD2 1 
ATOM   3197 C CE1 . PHE A 1 416 ? 179.092 170.681 136.330 1.00 30.59 ? 444 PHE A CE1 1 
ATOM   3198 C CE2 . PHE A 1 416 ? 177.633 172.310 135.385 1.00 30.59 ? 444 PHE A CE2 1 
ATOM   3199 C CZ  . PHE A 1 416 ? 178.750 171.516 135.287 1.00 30.59 ? 444 PHE A CZ  1 
ATOM   3200 N N   . ASN A 1 417 ? 175.150 170.010 141.562 1.00 36.34 ? 445 ASN A N   1 
ATOM   3201 C CA  . ASN A 1 417 ? 174.293 170.218 142.729 1.00 36.34 ? 445 ASN A CA  1 
ATOM   3202 C C   . ASN A 1 417 ? 175.051 170.187 144.054 1.00 36.34 ? 445 ASN A C   1 
ATOM   3203 O O   . ASN A 1 417 ? 174.827 171.087 144.884 1.00 36.34 ? 445 ASN A O   1 
ATOM   3204 C CB  . ASN A 1 417 ? 173.150 169.198 142.702 1.00 36.34 ? 445 ASN A CB  1 
ATOM   3205 C CG  . ASN A 1 417 ? 172.362 169.242 141.402 1.00 36.34 ? 445 ASN A CG  1 
ATOM   3206 O OD1 . ASN A 1 417 ? 172.432 170.214 140.654 1.00 36.34 ? 445 ASN A OD1 1 
ATOM   3207 N ND2 . ASN A 1 417 ? 171.615 168.182 141.125 1.00 36.34 ? 445 ASN A ND2 1 
ATOM   3208 N N   . PRO A 1 418 ? 175.924 169.209 144.336 1.00 39.98 ? 446 PRO A N   1 
ATOM   3209 C CA  . PRO A 1 418 ? 176.608 169.211 145.642 1.00 39.98 ? 446 PRO A CA  1 
ATOM   3210 C C   . PRO A 1 418 ? 177.452 170.447 145.890 1.00 39.98 ? 446 PRO A C   1 
ATOM   3211 O O   . PRO A 1 418 ? 177.560 170.889 147.040 1.00 39.98 ? 446 PRO A O   1 
ATOM   3212 C CB  . PRO A 1 418 ? 177.470 167.944 145.591 1.00 39.98 ? 446 PRO A CB  1 
ATOM   3213 C CG  . PRO A 1 418 ? 176.802 167.073 144.601 1.00 39.98 ? 446 PRO A CG  1 
ATOM   3214 C CD  . PRO A 1 418 ? 176.256 168.000 143.562 1.00 39.98 ? 446 PRO A CD  1 
ATOM   3215 N N   . LEU A 1 419 ? 178.063 171.015 144.851 1.00 45.81 ? 447 LEU A N   1 
ATOM   3216 C CA  . LEU A 1 419 ? 178.812 172.256 145.020 1.00 45.81 ? 447 LEU A CA  1 
ATOM   3217 C C   . LEU A 1 419 ? 177.891 173.397 145.440 1.00 45.81 ? 447 LEU A C   1 
ATOM   3218 O O   . LEU A 1 419 ? 178.219 174.184 146.338 1.00 45.81 ? 447 LEU A O   1 
ATOM   3219 C CB  . LEU A 1 419 ? 179.544 172.595 143.722 1.00 45.81 ? 447 LEU A CB  1 
ATOM   3220 C CG  . LEU A 1 419 ? 180.164 173.986 143.610 1.00 45.81 ? 447 LEU A CG  1 
ATOM   3221 C CD1 . LEU A 1 419 ? 181.189 174.213 144.709 1.00 45.81 ? 447 LEU A CD1 1 
ATOM   3222 C CD2 . LEU A 1 419 ? 180.790 174.170 142.238 1.00 45.81 ? 447 LEU A CD2 1 
ATOM   3223 N N   . ILE A 1 420 ? 176.722 173.495 144.804 1.00 38.01 ? 448 ILE A N   1 
ATOM   3224 C CA  . ILE A 1 420 ? 175.769 174.538 145.165 1.00 38.01 ? 448 ILE A CA  1 
ATOM   3225 C C   . ILE A 1 420 ? 175.290 174.342 146.596 1.00 38.01 ? 448 ILE A C   1 
ATOM   3226 O O   . ILE A 1 420 ? 175.056 175.311 147.328 1.00 38.01 ? 448 ILE A O   1 
ATOM   3227 C CB  . ILE A 1 420 ? 174.599 174.559 144.167 1.00 38.01 ? 448 ILE A CB  1 
ATOM   3228 C CG1 . ILE A 1 420 ? 175.124 174.717 142.742 1.00 38.01 ? 448 ILE A CG1 1 
ATOM   3229 C CG2 . ILE A 1 420 ? 173.658 175.694 144.482 1.00 38.01 ? 448 ILE A CG2 1 
ATOM   3230 C CD1 . ILE A 1 420 ? 175.959 175.955 142.538 1.00 38.01 ? 448 ILE A CD1 1 
ATOM   3231 N N   . TYR A 1 421 ? 175.140 173.087 147.021 1.00 44.50 ? 449 TYR A N   1 
ATOM   3232 C CA  . TYR A 1 421 ? 174.766 172.821 148.408 1.00 44.50 ? 449 TYR A CA  1 
ATOM   3233 C C   . TYR A 1 421 ? 175.867 173.233 149.375 1.00 44.50 ? 449 TYR A C   1 
ATOM   3234 O O   . TYR A 1 421 ? 175.592 173.865 150.400 1.00 44.50 ? 449 TYR A O   1 
ATOM   3235 C CB  . TYR A 1 421 ? 174.421 171.345 148.576 1.00 44.50 ? 449 TYR A CB  1 
ATOM   3236 C CG  . TYR A 1 421 ? 173.155 170.952 147.864 1.00 44.50 ? 449 TYR A CG  1 
ATOM   3237 C CD1 . TYR A 1 421 ? 172.265 171.914 147.418 1.00 44.50 ? 449 TYR A CD1 1 
ATOM   3238 C CD2 . TYR A 1 421 ? 172.881 169.625 147.576 1.00 44.50 ? 449 TYR A CD2 1 
ATOM   3239 C CE1 . TYR A 1 421 ? 171.117 171.567 146.759 1.00 44.50 ? 449 TYR A CE1 1 
ATOM   3240 C CE2 . TYR A 1 421 ? 171.738 169.269 146.902 1.00 44.50 ? 449 TYR A CE2 1 
ATOM   3241 C CZ  . TYR A 1 421 ? 170.859 170.247 146.496 1.00 44.50 ? 449 TYR A CZ  1 
ATOM   3242 O OH  . TYR A 1 421 ? 169.713 169.906 145.824 1.00 44.50 ? 449 TYR A OH  1 
ATOM   3243 N N   . CYS A 1 422 ? 177.122 172.897 149.066 1.00 50.41 ? 450 CYS A N   1 
ATOM   3244 C CA  . CYS A 1 422 ? 178.215 173.255 149.962 1.00 50.41 ? 450 CYS A CA  1 
ATOM   3245 C C   . CYS A 1 422 ? 178.467 174.755 149.987 1.00 50.41 ? 450 CYS A C   1 
ATOM   3246 O O   . CYS A 1 422 ? 179.113 175.246 150.918 1.00 50.41 ? 450 CYS A O   1 
ATOM   3247 C CB  . CYS A 1 422 ? 179.500 172.520 149.574 1.00 50.41 ? 450 CYS A CB  1 
ATOM   3248 S SG  . CYS A 1 422 ? 180.443 173.283 148.237 1.00 50.41 ? 450 CYS A SG  1 
ATOM   3249 N N   . ARG A 1 423 ? 177.984 175.492 148.984 1.00 49.34 ? 451 ARG A N   1 
ATOM   3250 C CA  . ARG A 1 423 ? 178.017 176.948 149.076 1.00 49.34 ? 451 ARG A CA  1 
ATOM   3251 C C   . ARG A 1 423 ? 177.141 177.452 150.218 1.00 49.34 ? 451 ARG A C   1 
ATOM   3252 O O   . ARG A 1 423 ? 177.436 178.493 150.815 1.00 49.34 ? 451 ARG A O   1 
ATOM   3253 C CB  . ARG A 1 423 ? 177.582 177.572 147.750 1.00 49.34 ? 451 ARG A CB  1 
ATOM   3254 C CG  . ARG A 1 423 ? 177.678 179.088 147.714 1.00 49.34 ? 451 ARG A CG  1 
ATOM   3255 C CD  . ARG A 1 423 ? 178.400 179.563 146.464 1.00 49.34 ? 451 ARG A CD  1 
ATOM   3256 N NE  . ARG A 1 423 ? 178.930 180.915 146.614 1.00 49.34 ? 451 ARG A NE  1 
ATOM   3257 C CZ  . ARG A 1 423 ? 179.752 181.497 145.747 1.00 49.34 ? 451 ARG A CZ  1 
ATOM   3258 N NH1 . ARG A 1 423 ? 180.141 180.845 144.660 1.00 49.34 ? 451 ARG A NH1 1 
ATOM   3259 N NH2 . ARG A 1 423 ? 180.186 182.730 145.964 1.00 49.34 ? 451 ARG A NH2 1 
ATOM   3260 N N   . SER A 1 424 ? 176.066 176.733 150.533 1.00 59.12 ? 452 SER A N   1 
ATOM   3261 C CA  . SER A 1 424 ? 175.210 177.113 151.648 1.00 59.12 ? 452 SER A CA  1 
ATOM   3262 C C   . SER A 1 424 ? 175.946 176.900 152.971 1.00 59.12 ? 452 SER A C   1 
ATOM   3263 O O   . SER A 1 424 ? 176.720 175.948 153.103 1.00 59.12 ? 452 SER A O   1 
ATOM   3264 C CB  . SER A 1 424 ? 173.916 176.298 151.626 1.00 59.12 ? 452 SER A CB  1 
ATOM   3265 O OG  . SER A 1 424 ? 172.987 176.771 152.585 1.00 59.12 ? 452 SER A OG  1 
ATOM   3266 N N   . PRO A 1 425 ? 175.724 177.765 153.970 1.00 64.23 ? 453 PRO A N   1 
ATOM   3267 C CA  . PRO A 1 425 ? 176.492 177.665 155.222 1.00 64.23 ? 453 PRO A CA  1 
ATOM   3268 C C   . PRO A 1 425 ? 176.195 176.418 156.042 1.00 64.23 ? 453 PRO A C   1 
ATOM   3269 O O   . PRO A 1 425 ? 177.124 175.724 156.471 1.00 64.23 ? 453 PRO A O   1 
ATOM   3270 C CB  . PRO A 1 425 ? 176.086 178.935 155.981 1.00 64.23 ? 453 PRO A CB  1 
ATOM   3271 C CG  . PRO A 1 425 ? 174.768 179.318 155.409 1.00 64.23 ? 453 PRO A CG  1 
ATOM   3272 C CD  . PRO A 1 425 ? 174.831 178.935 153.963 1.00 64.23 ? 453 PRO A CD  1 
ATOM   3273 N N   . ASP A 1 426 ? 174.914 176.132 156.289 1.00 66.87 ? 454 ASP A N   1 
ATOM   3274 C CA  . ASP A 1 426 ? 174.568 174.989 157.129 1.00 66.87 ? 454 ASP A CA  1 
ATOM   3275 C C   . ASP A 1 426 ? 174.992 173.677 156.482 1.00 66.87 ? 454 ASP A C   1 
ATOM   3276 O O   . ASP A 1 426 ? 175.498 172.777 157.163 1.00 66.87 ? 454 ASP A O   1 
ATOM   3277 C CB  . ASP A 1 426 ? 173.070 174.985 157.434 1.00 66.87 ? 454 ASP A CB  1 
ATOM   3278 C CG  . ASP A 1 426 ? 172.225 175.213 156.203 1.00 66.87 ? 454 ASP A CG  1 
ATOM   3279 O OD1 . ASP A 1 426 ? 170.998 174.992 156.278 1.00 66.87 ? 454 ASP A OD1 1 
ATOM   3280 O OD2 . ASP A 1 426 ? 172.786 175.616 155.164 1.00 66.87 ? 454 ASP A OD2 1 
ATOM   3281 N N   . PHE A 1 427 ? 174.801 173.546 155.169 1.00 62.48 ? 455 PHE A N   1 
ATOM   3282 C CA  . PHE A 1 427 ? 175.293 172.357 154.484 1.00 62.48 ? 455 PHE A CA  1 
ATOM   3283 C C   . PHE A 1 427 ? 176.814 172.291 154.510 1.00 62.48 ? 455 PHE A C   1 
ATOM   3284 O O   . PHE A 1 427 ? 177.382 171.197 154.591 1.00 62.48 ? 455 PHE A O   1 
ATOM   3285 C CB  . PHE A 1 427 ? 174.781 172.323 153.046 1.00 62.48 ? 455 PHE A CB  1 
ATOM   3286 C CG  . PHE A 1 427 ? 173.548 171.486 152.859 1.00 62.48 ? 455 PHE A CG  1 
ATOM   3287 C CD1 . PHE A 1 427 ? 173.605 170.110 152.973 1.00 62.48 ? 455 PHE A CD1 1 
ATOM   3288 C CD2 . PHE A 1 427 ? 172.333 172.076 152.559 1.00 62.48 ? 455 PHE A CD2 1 
ATOM   3289 C CE1 . PHE A 1 427 ? 172.473 169.338 152.798 1.00 62.48 ? 455 PHE A CE1 1 
ATOM   3290 C CE2 . PHE A 1 427 ? 171.199 171.308 152.383 1.00 62.48 ? 455 PHE A CE2 1 
ATOM   3291 C CZ  . PHE A 1 427 ? 171.270 169.938 152.503 1.00 62.48 ? 455 PHE A CZ  1 
ATOM   3292 N N   . ARG A 1 428 ? 177.488 173.442 154.438 1.00 63.46 ? 456 ARG A N   1 
ATOM   3293 C CA  . ARG A 1 428 ? 178.947 173.452 154.498 1.00 63.46 ? 456 ARG A CA  1 
ATOM   3294 C C   . ARG A 1 428 ? 179.442 172.931 155.841 1.00 63.46 ? 456 ARG A C   1 
ATOM   3295 O O   . ARG A 1 428 ? 180.337 172.081 155.898 1.00 63.46 ? 456 ARG A O   1 
ATOM   3296 C CB  . ARG A 1 428 ? 179.474 174.865 154.243 1.00 63.46 ? 456 ARG A CB  1 
ATOM   3297 C CG  . ARG A 1 428 ? 180.993 174.980 154.186 1.00 63.46 ? 456 ARG A CG  1 
ATOM   3298 C CD  . ARG A 1 428 ? 181.624 173.821 153.428 1.00 63.46 ? 456 ARG A CD  1 
ATOM   3299 N NE  . ARG A 1 428 ? 182.739 174.254 152.590 1.00 63.46 ? 456 ARG A NE  1 
ATOM   3300 C CZ  . ARG A 1 428 ? 183.572 173.426 151.968 1.00 63.46 ? 456 ARG A CZ  1 
ATOM   3301 N NH1 . ARG A 1 428 ? 183.420 172.114 152.088 1.00 63.46 ? 456 ARG A NH1 1 
ATOM   3302 N NH2 . ARG A 1 428 ? 184.558 173.909 151.225 1.00 63.46 ? 456 ARG A NH2 1 
ATOM   3303 N N   . ILE A 1 429 ? 178.868 173.431 156.938 1.00 66.98 ? 457 ILE A N   1 
ATOM   3304 C CA  . ILE A 1 429 ? 179.290 172.957 158.252 1.00 66.98 ? 457 ILE A CA  1 
ATOM   3305 C C   . ILE A 1 429 ? 178.848 171.516 158.468 1.00 66.98 ? 457 ILE A C   1 
ATOM   3306 O O   . ILE A 1 429 ? 179.471 170.778 159.241 1.00 66.98 ? 457 ILE A O   1 
ATOM   3307 C CB  . ILE A 1 429 ? 178.772 173.890 159.366 1.00 66.98 ? 457 ILE A CB  1 
ATOM   3308 C CG1 . ILE A 1 429 ? 179.518 173.626 160.676 1.00 66.98 ? 457 ILE A CG1 1 
ATOM   3309 C CG2 . ILE A 1 429 ? 177.279 173.716 159.579 1.00 66.98 ? 457 ILE A CG2 1 
ATOM   3310 C CD1 . ILE A 1 429 ? 180.860 174.314 160.767 1.00 66.98 ? 457 ILE A CD1 1 
ATOM   3311 N N   . ALA A 1 430 ? 177.778 171.086 157.795 1.00 66.96 ? 458 ALA A N   1 
ATOM   3312 C CA  . ALA A 1 430 ? 177.337 169.701 157.921 1.00 66.96 ? 458 ALA A CA  1 
ATOM   3313 C C   . ALA A 1 430 ? 178.363 168.733 157.343 1.00 66.96 ? 458 ALA A C   1 
ATOM   3314 O O   . ALA A 1 430 ? 178.608 167.666 157.917 1.00 66.96 ? 458 ALA A O   1 
ATOM   3315 C CB  . ALA A 1 430 ? 175.981 169.517 157.242 1.00 66.96 ? 458 ALA A CB  1 
ATOM   3316 N N   . PHE A 1 431 ? 179.003 169.136 156.233 1.00 63.99 ? 459 PHE A N   1 
ATOM   3317 C CA  . PHE A 1 431 ? 179.946 168.250 155.507 1.00 63.99 ? 459 PHE A CA  1 
ATOM   3318 C C   . PHE A 1 431 ? 181.296 168.334 156.178 1.00 63.99 ? 459 PHE A C   1 
ATOM   3319 O O   . PHE A 1 431 ? 182.289 168.307 155.455 1.00 63.99 ? 459 PHE A O   1 
ATOM   3320 C CB  . PHE A 1 431 ? 180.244 168.814 154.117 1.00 63.99 ? 459 PHE A CB  1 
ATOM   3321 C CG  . PHE A 1 431 ? 179.112 168.804 153.124 1.00 63.99 ? 459 PHE A CG  1 
ATOM   3322 C CD1 . PHE A 1 431 ? 178.007 167.990 153.301 1.00 63.99 ? 459 PHE A CD1 1 
ATOM   3323 C CD2 . PHE A 1 431 ? 179.165 169.602 151.996 1.00 63.99 ? 459 PHE A CD2 1 
ATOM   3324 C CE1 . PHE A 1 431 ? 176.973 167.988 152.380 1.00 63.99 ? 459 PHE A CE1 1 
ATOM   3325 C CE2 . PHE A 1 431 ? 178.131 169.599 151.076 1.00 63.99 ? 459 PHE A CE2 1 
ATOM   3326 C CZ  . PHE A 1 431 ? 177.038 168.792 151.268 1.00 63.99 ? 459 PHE A CZ  1 
ATOM   3327 N N   . THR B 2 13  ? 187.118 175.067 177.049 1.00 29.35 ? 13  THR B N   1 
ATOM   3328 C CA  . THR B 2 13  ? 187.615 173.820 176.485 1.00 29.35 ? 13  THR B CA  1 
ATOM   3329 C C   . THR B 2 13  ? 186.833 172.635 177.024 1.00 29.35 ? 13  THR B C   1 
ATOM   3330 O O   . THR B 2 13  ? 185.609 172.573 176.914 1.00 29.35 ? 13  THR B O   1 
ATOM   3331 C CB  . THR B 2 13  ? 189.100 173.606 176.806 1.00 29.35 ? 13  THR B CB  1 
ATOM   3332 O OG1 . THR B 2 13  ? 189.240 173.239 178.183 1.00 29.35 ? 13  THR B OG1 1 
ATOM   3333 C CG2 . THR B 2 13  ? 189.884 174.881 176.550 1.00 29.35 ? 13  THR B CG2 1 
ATOM   3334 N N   . ASP B 2 14  ? 187.563 171.685 177.601 1.00 31.22 ? 14  ASP B N   1 
ATOM   3335 C CA  . ASP B 2 14  ? 186.950 170.555 178.281 1.00 31.22 ? 14  ASP B CA  1 
ATOM   3336 C C   . ASP B 2 14  ? 186.630 170.883 179.733 1.00 31.22 ? 14  ASP B C   1 
ATOM   3337 O O   . ASP B 2 14  ? 185.621 170.411 180.265 1.00 31.22 ? 14  ASP B O   1 
ATOM   3338 C CB  . ASP B 2 14  ? 187.870 169.332 178.209 1.00 31.22 ? 14  ASP B CB  1 
ATOM   3339 C CG  . ASP B 2 14  ? 187.748 168.580 176.897 1.00 31.22 ? 14  ASP B CG  1 
ATOM   3340 O OD1 . ASP B 2 14  ? 186.609 168.361 176.438 1.00 31.22 ? 14  ASP B OD1 1 
ATOM   3341 O OD2 . ASP B 2 14  ? 188.793 168.207 176.326 1.00 31.22 ? 14  ASP B OD2 1 
ATOM   3342 N N   . ARG B 2 15  ? 187.471 171.688 180.378 1.00 24.44 ? 15  ARG B N   1 
ATOM   3343 C CA  . ARG B 2 15  ? 187.285 172.031 181.786 1.00 24.44 ? 15  ARG B CA  1 
ATOM   3344 C C   . ARG B 2 15  ? 188.050 173.319 182.043 1.00 24.44 ? 15  ARG B C   1 
ATOM   3345 O O   . ARG B 2 15  ? 189.281 173.330 181.951 1.00 24.44 ? 15  ARG B O   1 
ATOM   3346 C CB  . ARG B 2 15  ? 187.781 170.909 182.686 1.00 24.44 ? 15  ARG B CB  1 
ATOM   3347 C CG  . ARG B 2 15  ? 186.726 169.899 183.089 1.00 24.44 ? 15  ARG B CG  1 
ATOM   3348 C CD  . ARG B 2 15  ? 187.310 168.864 184.029 1.00 24.44 ? 15  ARG B CD  1 
ATOM   3349 N NE  . ARG B 2 15  ? 187.180 169.244 185.430 1.00 24.44 ? 15  ARG B NE  1 
ATOM   3350 C CZ  . ARG B 2 15  ? 186.028 169.285 186.088 1.00 24.44 ? 15  ARG B CZ  1 
ATOM   3351 N NH1 . ARG B 2 15  ? 184.900 168.960 185.479 1.00 24.44 ? 15  ARG B NH1 1 
ATOM   3352 N NH2 . ARG B 2 15  ? 186.006 169.640 187.362 1.00 24.44 ? 15  ARG B NH2 1 
ATOM   3353 N N   . VAL B 2 16  ? 187.330 174.395 182.362 1.00 21.53 ? 16  VAL B N   1 
ATOM   3354 C CA  . VAL B 2 16  ? 187.985 175.686 182.549 1.00 21.53 ? 16  VAL B CA  1 
ATOM   3355 C C   . VAL B 2 16  ? 188.820 175.692 183.823 1.00 21.53 ? 16  VAL B C   1 
ATOM   3356 O O   . VAL B 2 16  ? 189.968 176.151 183.823 1.00 21.53 ? 16  VAL B O   1 
ATOM   3357 C CB  . VAL B 2 16  ? 186.945 176.814 182.540 1.00 21.53 ? 16  VAL B CB  1 
ATOM   3358 C CG1 . VAL B 2 16  ? 187.625 178.149 182.745 1.00 21.53 ? 16  VAL B CG1 1 
ATOM   3359 C CG2 . VAL B 2 16  ? 186.188 176.800 181.233 1.00 21.53 ? 16  VAL B CG2 1 
ATOM   3360 N N   . VAL B 2 17  ? 188.269 175.189 184.924 1.00 23.49 ? 17  VAL B N   1 
ATOM   3361 C CA  . VAL B 2 17  ? 189.024 174.979 186.155 1.00 23.49 ? 17  VAL B CA  1 
ATOM   3362 C C   . VAL B 2 17  ? 189.029 173.484 186.441 1.00 23.49 ? 17  VAL B C   1 
ATOM   3363 O O   . VAL B 2 17  ? 187.970 172.846 186.471 1.00 23.49 ? 17  VAL B O   1 
ATOM   3364 C CB  . VAL B 2 17  ? 188.459 175.786 187.337 1.00 23.49 ? 17  VAL B CB  1 
ATOM   3365 C CG1 . VAL B 2 17  ? 187.030 175.408 187.636 1.00 23.49 ? 17  VAL B CG1 1 
ATOM   3366 C CG2 . VAL B 2 17  ? 189.320 175.584 188.567 1.00 23.49 ? 17  VAL B CG2 1 
ATOM   3367 N N   . LYS B 2 18  ? 190.225 172.918 186.609 1.00 28.58 ? 18  LYS B N   1 
ATOM   3368 C CA  . LYS B 2 18  ? 190.379 171.482 186.784 1.00 28.58 ? 18  LYS B CA  1 
ATOM   3369 C C   . LYS B 2 18  ? 190.790 171.085 188.192 1.00 28.58 ? 18  LYS B C   1 
ATOM   3370 O O   . LYS B 2 18  ? 190.777 169.889 188.505 1.00 28.58 ? 18  LYS B O   1 
ATOM   3371 C CB  . LYS B 2 18  ? 191.411 170.933 185.789 1.00 28.58 ? 18  LYS B CB  1 
ATOM   3372 C CG  . LYS B 2 18  ? 190.967 170.996 184.343 1.00 28.58 ? 18  LYS B CG  1 
ATOM   3373 C CD  . LYS B 2 18  ? 192.042 170.469 183.411 1.00 28.58 ? 18  LYS B CD  1 
ATOM   3374 C CE  . LYS B 2 18  ? 191.541 170.402 181.979 1.00 28.58 ? 18  LYS B CE  1 
ATOM   3375 N NZ  . LYS B 2 18  ? 191.247 171.754 181.434 1.00 28.58 ? 18  LYS B NZ  1 
ATOM   3376 N N   . ALA B 2 19  ? 191.149 172.047 189.046 1.00 28.02 ? 19  ALA B N   1 
ATOM   3377 C CA  . ALA B 2 19  ? 191.582 171.721 190.398 1.00 28.02 ? 19  ALA B CA  1 
ATOM   3378 C C   . ALA B 2 19  ? 190.499 171.016 191.199 1.00 28.02 ? 19  ALA B C   1 
ATOM   3379 O O   . ALA B 2 19  ? 190.820 170.300 192.152 1.00 28.02 ? 19  ALA B O   1 
ATOM   3380 C CB  . ALA B 2 19  ? 192.027 172.988 191.129 1.00 28.02 ? 19  ALA B CB  1 
ATOM   3381 N N   . VAL B 2 20  ? 189.233 171.198 190.840 1.00 26.89 ? 20  VAL B N   1 
ATOM   3382 C CA  . VAL B 2 20  ? 188.140 170.511 191.520 1.00 26.89 ? 20  VAL B CA  1 
ATOM   3383 C C   . VAL B 2 20  ? 187.987 169.123 190.907 1.00 26.89 ? 20  VAL B C   1 
ATOM   3384 O O   . VAL B 2 20  ? 188.107 168.968 189.683 1.00 26.89 ? 20  VAL B O   1 
ATOM   3385 C CB  . VAL B 2 20  ? 186.834 171.318 191.449 1.00 26.89 ? 20  VAL B CB  1 
ATOM   3386 C CG1 . VAL B 2 20  ? 187.030 172.665 192.098 1.00 26.89 ? 20  VAL B CG1 1 
ATOM   3387 C CG2 . VAL B 2 20  ? 186.371 171.487 190.026 1.00 26.89 ? 20  VAL B CG2 1 
ATOM   3388 N N   . PRO B 2 21  ? 187.758 168.090 191.710 1.00 27.30 ? 21  PRO B N   1 
ATOM   3389 C CA  . PRO B 2 21  ? 187.612 166.742 191.156 1.00 27.30 ? 21  PRO B CA  1 
ATOM   3390 C C   . PRO B 2 21  ? 186.333 166.600 190.348 1.00 27.30 ? 21  PRO B C   1 
ATOM   3391 O O   . PRO B 2 21  ? 185.417 167.421 190.421 1.00 27.30 ? 21  PRO B O   1 
ATOM   3392 C CB  . PRO B 2 21  ? 187.584 165.849 192.400 1.00 27.30 ? 21  PRO B CB  1 
ATOM   3393 C CG  . PRO B 2 21  ? 188.204 166.675 193.480 1.00 27.30 ? 21  PRO B CG  1 
ATOM   3394 C CD  . PRO B 2 21  ? 187.809 168.078 193.180 1.00 27.30 ? 21  PRO B CD  1 
ATOM   3395 N N   . PHE B 2 22  ? 186.290 165.533 189.556 1.00 28.02 ? 22  PHE B N   1 
ATOM   3396 C CA  . PHE B 2 22  ? 185.208 165.152 188.658 1.00 28.02 ? 22  PHE B CA  1 
ATOM   3397 C C   . PHE B 2 22  ? 184.388 164.018 189.272 1.00 28.02 ? 22  PHE B C   1 
ATOM   3398 O O   . PHE B 2 22  ? 184.956 163.062 189.806 1.00 28.02 ? 22  PHE B O   1 
ATOM   3399 C CB  . PHE B 2 22  ? 185.774 164.711 187.309 1.00 28.02 ? 22  PHE B CB  1 
ATOM   3400 C CG  . PHE B 2 22  ? 184.806 164.836 186.166 1.00 28.02 ? 22  PHE B CG  1 
ATOM   3401 C CD1 . PHE B 2 22  ? 184.999 165.789 185.185 1.00 28.02 ? 22  PHE B CD1 1 
ATOM   3402 C CD2 . PHE B 2 22  ? 183.720 163.990 186.060 1.00 28.02 ? 22  PHE B CD2 1 
ATOM   3403 C CE1 . PHE B 2 22  ? 184.114 165.905 184.130 1.00 28.02 ? 22  PHE B CE1 1 
ATOM   3404 C CE2 . PHE B 2 22  ? 182.833 164.101 185.009 1.00 28.02 ? 22  PHE B CE2 1 
ATOM   3405 C CZ  . PHE B 2 22  ? 183.031 165.059 184.043 1.00 28.02 ? 22  PHE B CZ  1 
ATOM   3406 N N   . PRO B 2 23  ? 183.060 164.090 189.233 1.00 23.48 ? 23  PRO B N   1 
ATOM   3407 C CA  . PRO B 2 23  ? 182.241 162.983 189.727 1.00 23.48 ? 23  PRO B CA  1 
ATOM   3408 C C   . PRO B 2 23  ? 182.279 161.807 188.769 1.00 23.48 ? 23  PRO B C   1 
ATOM   3409 O O   . PRO B 2 23  ? 182.080 161.980 187.559 1.00 23.48 ? 23  PRO B O   1 
ATOM   3410 C CB  . PRO B 2 23  ? 180.829 163.589 189.798 1.00 23.48 ? 23  PRO B CB  1 
ATOM   3411 C CG  . PRO B 2 23  ? 181.026 165.053 189.727 1.00 23.48 ? 23  PRO B CG  1 
ATOM   3412 C CD  . PRO B 2 23  ? 182.237 165.257 188.890 1.00 23.48 ? 23  PRO B CD  1 
ATOM   3413 N N   . PRO B 2 24  ? 182.534 160.598 189.266 1.00 28.51 ? 24  PRO B N   1 
ATOM   3414 C CA  . PRO B 2 24  ? 182.436 159.418 188.403 1.00 28.51 ? 24  PRO B CA  1 
ATOM   3415 C C   . PRO B 2 24  ? 181.043 159.291 187.807 1.00 28.51 ? 24  PRO B C   1 
ATOM   3416 O O   . PRO B 2 24  ? 180.037 159.538 188.473 1.00 28.51 ? 24  PRO B O   1 
ATOM   3417 C CB  . PRO B 2 24  ? 182.751 158.262 189.354 1.00 28.51 ? 24  PRO B CB  1 
ATOM   3418 C CG  . PRO B 2 24  ? 183.627 158.871 190.382 1.00 28.51 ? 24  PRO B CG  1 
ATOM   3419 C CD  . PRO B 2 24  ? 183.114 160.268 190.577 1.00 28.51 ? 24  PRO B CD  1 
ATOM   3420 N N   . SER B 2 25  ? 180.994 158.896 186.535 1.00 33.43 ? 25  SER B N   1 
ATOM   3421 C CA  . SER B 2 25  ? 179.758 158.893 185.766 1.00 33.43 ? 25  SER B CA  1 
ATOM   3422 C C   . SER B 2 25  ? 179.289 157.491 185.399 1.00 33.43 ? 25  SER B C   1 
ATOM   3423 O O   . SER B 2 25  ? 178.527 157.333 184.440 1.00 33.43 ? 25  SER B O   1 
ATOM   3424 C CB  . SER B 2 25  ? 179.919 159.731 184.499 1.00 33.43 ? 25  SER B CB  1 
ATOM   3425 O OG  . SER B 2 25  ? 178.868 159.466 183.588 1.00 33.43 ? 25  SER B OG  1 
ATOM   3426 N N   . HIS B 2 26  ? 179.726 156.469 186.129 1.00 36.31 ? 26  HIS B N   1 
ATOM   3427 C CA  . HIS B 2 26  ? 179.266 155.106 185.904 1.00 36.31 ? 26  HIS B CA  1 
ATOM   3428 C C   . HIS B 2 26  ? 178.617 154.580 187.176 1.00 36.31 ? 26  HIS B C   1 
ATOM   3429 O O   . HIS B 2 26  ? 179.195 154.677 188.263 1.00 36.31 ? 26  HIS B O   1 
ATOM   3430 C CB  . HIS B 2 26  ? 180.415 154.196 185.445 1.00 36.31 ? 26  HIS B CB  1 
ATOM   3431 C CG  . HIS B 2 26  ? 181.210 153.589 186.559 1.00 36.31 ? 26  HIS B CG  1 
ATOM   3432 N ND1 . HIS B 2 26  ? 182.082 154.319 187.337 1.00 36.31 ? 26  HIS B ND1 1 
ATOM   3433 C CD2 . HIS B 2 26  ? 181.281 152.315 187.010 1.00 36.31 ? 26  HIS B CD2 1 
ATOM   3434 C CE1 . HIS B 2 26  ? 182.646 153.522 188.227 1.00 36.31 ? 26  HIS B CE1 1 
ATOM   3435 N NE2 . HIS B 2 26  ? 182.178 152.301 188.049 1.00 36.31 ? 26  HIS B NE2 1 
ATOM   3436 N N   . ARG B 2 27  ? 177.405 154.053 187.039 1.00 39.17 ? 27  ARG B N   1 
ATOM   3437 C CA  . ARG B 2 27  ? 176.688 153.491 188.169 1.00 39.17 ? 27  ARG B CA  1 
ATOM   3438 C C   . ARG B 2 27  ? 177.262 152.124 188.535 1.00 39.17 ? 27  ARG B C   1 
ATOM   3439 O O   . ARG B 2 27  ? 178.071 151.543 187.808 1.00 39.17 ? 27  ARG B O   1 
ATOM   3440 C CB  . ARG B 2 27  ? 175.198 153.378 187.852 1.00 39.17 ? 27  ARG B CB  1 
ATOM   3441 C CG  . ARG B 2 27  ? 174.487 154.712 187.721 1.00 39.17 ? 27  ARG B CG  1 
ATOM   3442 C CD  . ARG B 2 27  ? 172.979 154.538 187.802 1.00 39.17 ? 27  ARG B CD  1 
ATOM   3443 N NE  . ARG B 2 27  ? 172.286 155.815 187.938 1.00 39.17 ? 27  ARG B NE  1 
ATOM   3444 C CZ  . ARG B 2 27  ? 171.005 155.938 188.270 1.00 39.17 ? 27  ARG B CZ  1 
ATOM   3445 N NH1 . ARG B 2 27  ? 170.274 154.858 188.506 1.00 39.17 ? 27  ARG B NH1 1 
ATOM   3446 N NH2 . ARG B 2 27  ? 170.455 157.139 188.371 1.00 39.17 ? 27  ARG B NH2 1 
ATOM   3447 N N   . LEU B 2 28  ? 176.836 151.609 189.685 1.00 32.99 ? 28  LEU B N   1 
ATOM   3448 C CA  . LEU B 2 28  ? 177.288 150.316 190.189 1.00 32.99 ? 28  LEU B CA  1 
ATOM   3449 C C   . LEU B 2 28  ? 176.091 149.373 190.195 1.00 32.99 ? 28  LEU B C   1 
ATOM   3450 O O   . LEU B 2 28  ? 175.128 149.592 190.937 1.00 32.99 ? 28  LEU B O   1 
ATOM   3451 C CB  . LEU B 2 28  ? 177.893 150.452 191.585 1.00 32.99 ? 28  LEU B CB  1 
ATOM   3452 C CG  . LEU B 2 28  ? 179.365 150.852 191.708 1.00 32.99 ? 28  LEU B CG  1 
ATOM   3453 C CD1 . LEU B 2 28  ? 179.635 152.177 191.031 1.00 32.99 ? 28  LEU B CD1 1 
ATOM   3454 C CD2 . LEU B 2 28  ? 179.784 150.922 193.163 1.00 32.99 ? 28  LEU B CD2 1 
ATOM   3455 N N   . THR B 2 29  ? 176.144 148.336 189.364 1.00 41.01 ? 29  THR B N   1 
ATOM   3456 C CA  . THR B 2 29  ? 175.020 147.411 189.204 1.00 41.01 ? 29  THR B CA  1 
ATOM   3457 C C   . THR B 2 29  ? 175.229 146.135 190.021 1.00 41.01 ? 29  THR B C   1 
ATOM   3458 O O   . THR B 2 29  ? 175.414 145.042 189.486 1.00 41.01 ? 29  THR B O   1 
ATOM   3459 C CB  . THR B 2 29  ? 174.802 147.087 187.729 1.00 41.01 ? 29  THR B CB  1 
ATOM   3460 O OG1 . THR B 2 29  ? 176.030 146.625 187.150 1.00 41.01 ? 29  THR B OG1 1 
ATOM   3461 C CG2 . THR B 2 29  ? 174.309 148.316 186.978 1.00 41.01 ? 29  THR B CG2 1 
ATOM   3462 N N   . ALA B 2 30  ? 175.208 146.297 191.341 1.00 38.68 ? 30  ALA B N   1 
ATOM   3463 C CA  . ALA B 2 30  ? 175.076 145.210 192.309 1.00 38.68 ? 30  ALA B CA  1 
ATOM   3464 C C   . ALA B 2 30  ? 176.169 144.158 192.199 1.00 38.68 ? 30  ALA B C   1 
ATOM   3465 O O   . ALA B 2 30  ? 176.073 143.107 192.843 1.00 38.68 ? 30  ALA B O   1 
ATOM   3466 C CB  . ALA B 2 30  ? 173.706 144.531 192.197 1.00 38.68 ? 30  ALA B CB  1 
ATOM   3467 N N   . LYS B 2 31  ? 177.207 144.399 191.404 1.00 36.59 ? 31  LYS B N   1 
ATOM   3468 C CA  . LYS B 2 31  ? 178.244 143.393 191.228 1.00 36.59 ? 31  LYS B CA  1 
ATOM   3469 C C   . LYS B 2 31  ? 179.461 143.651 192.098 1.00 36.59 ? 31  LYS B C   1 
ATOM   3470 O O   . LYS B 2 31  ? 180.176 142.705 192.447 1.00 36.59 ? 31  LYS B O   1 
ATOM   3471 C CB  . LYS B 2 31  ? 178.668 143.321 189.758 1.00 36.59 ? 31  LYS B CB  1 
ATOM   3472 N N   . GLU B 2 32  ? 179.712 144.907 192.456 1.00 35.50 ? 32  GLU B N   1 
ATOM   3473 C CA  . GLU B 2 32  ? 180.850 145.259 193.291 1.00 35.50 ? 32  GLU B CA  1 
ATOM   3474 C C   . GLU B 2 32  ? 180.469 145.621 194.716 1.00 35.50 ? 32  GLU B C   1 
ATOM   3475 O O   . GLU B 2 32  ? 181.246 145.351 195.632 1.00 35.50 ? 32  GLU B O   1 
ATOM   3476 C CB  . GLU B 2 32  ? 181.623 146.426 192.668 1.00 35.50 ? 32  GLU B CB  1 
ATOM   3477 C CG  . GLU B 2 32  ? 181.827 146.301 191.166 1.00 35.50 ? 32  GLU B CG  1 
ATOM   3478 C CD  . GLU B 2 32  ? 180.720 146.956 190.367 1.00 35.50 ? 32  GLU B CD  1 
ATOM   3479 O OE1 . GLU B 2 32  ? 181.030 147.731 189.440 1.00 35.50 ? 32  GLU B OE1 1 
ATOM   3480 O OE2 . GLU B 2 32  ? 179.537 146.695 190.669 1.00 35.50 ? 32  GLU B OE2 1 
ATOM   3481 N N   . VAL B 2 33  ? 179.286 146.203 194.929 1.00 31.99 ? 33  VAL B N   1 
ATOM   3482 C CA  . VAL B 2 33  ? 178.873 146.581 196.275 1.00 31.99 ? 33  VAL B CA  1 
ATOM   3483 C C   . VAL B 2 33  ? 178.522 145.369 197.127 1.00 31.99 ? 33  VAL B C   1 
ATOM   3484 O O   . VAL B 2 33  ? 178.501 145.470 198.357 1.00 31.99 ? 33  VAL B O   1 
ATOM   3485 C CB  . VAL B 2 33  ? 177.680 147.553 196.226 1.00 31.99 ? 33  VAL B CB  1 
ATOM   3486 C CG1 . VAL B 2 33  ? 178.061 148.821 195.500 1.00 31.99 ? 33  VAL B CG1 1 
ATOM   3487 C CG2 . VAL B 2 33  ? 176.488 146.901 195.566 1.00 31.99 ? 33  VAL B CG2 1 
ATOM   3488 N N   . PHE B 2 34  ? 178.246 144.227 196.512 1.00 31.84 ? 34  PHE B N   1 
ATOM   3489 C CA  . PHE B 2 34  ? 177.790 143.035 197.204 1.00 31.84 ? 34  PHE B CA  1 
ATOM   3490 C C   . PHE B 2 34  ? 178.880 141.966 197.200 1.00 31.84 ? 34  PHE B C   1 
ATOM   3491 O O   . PHE B 2 34  ? 180.017 142.202 196.777 1.00 31.84 ? 34  PHE B O   1 
ATOM   3492 C CB  . PHE B 2 34  ? 176.500 142.525 196.560 1.00 31.84 ? 34  PHE B CB  1 
ATOM   3493 C CG  . PHE B 2 34  ? 175.251 143.030 197.219 1.00 31.84 ? 34  PHE B CG  1 
ATOM   3494 C CD1 . PHE B 2 34  ? 174.771 142.435 198.370 1.00 31.84 ? 34  PHE B CD1 1 
ATOM   3495 C CD2 . PHE B 2 34  ? 174.556 144.100 196.687 1.00 31.84 ? 34  PHE B CD2 1 
ATOM   3496 C CE1 . PHE B 2 34  ? 173.621 142.897 198.976 1.00 31.84 ? 34  PHE B CE1 1 
ATOM   3497 C CE2 . PHE B 2 34  ? 173.406 144.566 197.290 1.00 31.84 ? 34  PHE B CE2 1 
ATOM   3498 C CZ  . PHE B 2 34  ? 172.940 143.964 198.436 1.00 31.84 ? 34  PHE B CZ  1 
ATOM   3499 N N   . ASP B 2 35  ? 178.532 140.784 197.695 1.00 41.80 ? 35  ASP B N   1 
ATOM   3500 C CA  . ASP B 2 35  ? 179.419 139.630 197.641 1.00 41.80 ? 35  ASP B CA  1 
ATOM   3501 C C   . ASP B 2 35  ? 178.645 138.364 197.294 1.00 41.80 ? 35  ASP B C   1 
ATOM   3502 O O   . ASP B 2 35  ? 178.962 137.279 197.782 1.00 41.80 ? 35  ASP B O   1 
ATOM   3503 C CB  . ASP B 2 35  ? 180.151 139.444 198.967 1.00 41.80 ? 35  ASP B CB  1 
ATOM   3504 C CG  . ASP B 2 35  ? 181.517 140.083 198.965 1.00 41.80 ? 35  ASP B CG  1 
ATOM   3505 O OD1 . ASP B 2 35  ? 182.072 140.282 197.865 1.00 41.80 ? 35  ASP B OD1 1 
ATOM   3506 O OD2 . ASP B 2 35  ? 182.041 140.375 200.061 1.00 41.80 ? 35  ASP B OD2 1 
ATOM   3507 N N   . GLY B 2 38  ? 175.206 137.008 201.796 1.00 36.85 ? 38  GLY B N   1 
ATOM   3508 C CA  . GLY B 2 38  ? 175.357 138.105 200.859 1.00 36.85 ? 38  GLY B CA  1 
ATOM   3509 C C   . GLY B 2 38  ? 175.756 139.407 201.522 1.00 36.85 ? 38  GLY B C   1 
ATOM   3510 O O   . GLY B 2 38  ? 175.017 140.387 201.474 1.00 36.85 ? 38  GLY B O   1 
ATOM   3511 N N   . LYS B 2 39  ? 176.928 139.413 202.143 1.00 37.77 ? 39  LYS B N   1 
ATOM   3512 C CA  . LYS B 2 39  ? 177.424 140.611 202.803 1.00 37.77 ? 39  LYS B CA  1 
ATOM   3513 C C   . LYS B 2 39  ? 177.635 141.718 201.777 1.00 37.77 ? 39  LYS B C   1 
ATOM   3514 O O   . LYS B 2 39  ? 178.191 141.459 200.702 1.00 37.77 ? 39  LYS B O   1 
ATOM   3515 C CB  . LYS B 2 39  ? 178.741 140.322 203.517 1.00 37.77 ? 39  LYS B CB  1 
ATOM   3516 C CG  . LYS B 2 39  ? 178.637 139.372 204.686 1.00 37.77 ? 39  LYS B CG  1 
ATOM   3517 C CD  . LYS B 2 39  ? 179.967 139.283 205.401 1.00 37.77 ? 39  LYS B CD  1 
ATOM   3518 C CE  . LYS B 2 39  ? 179.838 138.555 206.719 1.00 37.77 ? 39  LYS B CE  1 
ATOM   3519 N NZ  . LYS B 2 39  ? 181.088 138.671 207.516 1.00 37.77 ? 39  LYS B NZ  1 
ATOM   3520 N N   . PRO B 2 40  ? 177.215 142.950 202.058 1.00 26.04 ? 40  PRO B N   1 
ATOM   3521 C CA  . PRO B 2 40  ? 177.536 144.057 201.156 1.00 26.04 ? 40  PRO B CA  1 
ATOM   3522 C C   . PRO B 2 40  ? 178.914 144.625 201.451 1.00 26.04 ? 40  PRO B C   1 
ATOM   3523 O O   . PRO B 2 40  ? 179.398 144.598 202.584 1.00 26.04 ? 40  PRO B O   1 
ATOM   3524 C CB  . PRO B 2 40  ? 176.434 145.079 201.459 1.00 26.04 ? 40  PRO B CB  1 
ATOM   3525 C CG  . PRO B 2 40  ? 176.040 144.806 202.857 1.00 26.04 ? 40  PRO B CG  1 
ATOM   3526 C CD  . PRO B 2 40  ? 176.406 143.389 203.204 1.00 26.04 ? 40  PRO B CD  1 
ATOM   3527 N N   . ARG B 2 41  ? 179.566 145.120 200.403 1.00 27.18 ? 41  ARG B N   1 
ATOM   3528 C CA  . ARG B 2 41  ? 180.855 145.778 200.571 1.00 27.18 ? 41  ARG B CA  1 
ATOM   3529 C C   . ARG B 2 41  ? 180.638 147.211 201.036 1.00 27.18 ? 41  ARG B C   1 
ATOM   3530 O O   . ARG B 2 41  ? 179.847 147.953 200.448 1.00 27.18 ? 41  ARG B O   1 
ATOM   3531 C CB  . ARG B 2 41  ? 181.643 145.751 199.264 1.00 27.18 ? 41  ARG B CB  1 
ATOM   3532 N N   . VAL B 2 42  ? 181.341 147.600 202.095 1.00 21.80 ? 42  VAL B N   1 
ATOM   3533 C CA  . VAL B 2 42  ? 181.119 148.876 202.753 1.00 21.80 ? 42  VAL B CA  1 
ATOM   3534 C C   . VAL B 2 42  ? 182.202 149.890 202.411 1.00 21.80 ? 42  VAL B C   1 
ATOM   3535 O O   . VAL B 2 42  ? 181.893 151.041 202.095 1.00 21.80 ? 42  VAL B O   1 
ATOM   3536 C CB  . VAL B 2 42  ? 181.002 148.687 204.279 1.00 21.80 ? 42  VAL B CB  1 
ATOM   3537 C CG1 . VAL B 2 42  ? 181.251 149.993 204.995 1.00 21.80 ? 42  VAL B CG1 1 
ATOM   3538 C CG2 . VAL B 2 42  ? 179.630 148.160 204.630 1.00 21.80 ? 42  VAL B CG2 1 
ATOM   3539 N N   . ASP B 2 43  ? 183.474 149.488 202.460 1.00 19.56 ? 43  ASP B N   1 
ATOM   3540 C CA  . ASP B 2 43  ? 184.555 150.443 202.232 1.00 19.56 ? 43  ASP B CA  1 
ATOM   3541 C C   . ASP B 2 43  ? 184.483 151.048 200.837 1.00 19.56 ? 43  ASP B C   1 
ATOM   3542 O O   . ASP B 2 43  ? 184.655 152.261 200.671 1.00 19.56 ? 43  ASP B O   1 
ATOM   3543 C CB  . ASP B 2 43  ? 185.905 149.771 202.452 1.00 19.56 ? 43  ASP B CB  1 
ATOM   3544 C CG  . ASP B 2 43  ? 186.127 149.389 203.891 1.00 19.56 ? 43  ASP B CG  1 
ATOM   3545 O OD1 . ASP B 2 43  ? 185.505 150.023 204.767 1.00 19.56 ? 43  ASP B OD1 1 
ATOM   3546 O OD2 . ASP B 2 43  ? 186.916 148.457 204.147 1.00 19.56 ? 43  ASP B OD2 1 
ATOM   3547 N N   . ILE B 2 44  ? 184.226 150.225 199.819 1.00 19.65 ? 44  ILE B N   1 
ATOM   3548 C CA  . ILE B 2 44  ? 184.121 150.783 198.477 1.00 19.65 ? 44  ILE B CA  1 
ATOM   3549 C C   . ILE B 2 44  ? 182.840 151.590 198.334 1.00 19.65 ? 44  ILE B C   1 
ATOM   3550 O O   . ILE B 2 44  ? 182.809 152.582 197.601 1.00 19.65 ? 44  ILE B O   1 
ATOM   3551 C CB  . ILE B 2 44  ? 184.220 149.688 197.403 1.00 19.65 ? 44  ILE B CB  1 
ATOM   3552 C CG1 . ILE B 2 44  ? 183.063 148.709 197.510 1.00 19.65 ? 44  ILE B CG1 1 
ATOM   3553 C CG2 . ILE B 2 44  ? 185.534 148.943 197.533 1.00 19.65 ? 44  ILE B CG2 1 
ATOM   3554 C CD1 . ILE B 2 44  ? 182.996 147.775 196.341 1.00 19.65 ? 44  ILE B CD1 1 
ATOM   3555 N N   . LEU B 2 45  ? 181.770 151.203 199.031 1.00 18.19 ? 45  LEU B N   1 
ATOM   3556 C CA  . LEU B 2 45  ? 180.554 152.010 199.000 1.00 18.19 ? 45  LEU B CA  1 
ATOM   3557 C C   . LEU B 2 45  ? 180.779 153.375 199.635 1.00 18.19 ? 45  LEU B C   1 
ATOM   3558 O O   . LEU B 2 45  ? 180.281 154.389 199.131 1.00 18.19 ? 45  LEU B O   1 
ATOM   3559 C CB  . LEU B 2 45  ? 179.410 151.281 199.694 1.00 18.19 ? 45  LEU B CB  1 
ATOM   3560 C CG  . LEU B 2 45  ? 178.034 151.850 199.358 1.00 18.19 ? 45  LEU B CG  1 
ATOM   3561 C CD1 . LEU B 2 45  ? 177.934 152.126 197.873 1.00 18.19 ? 45  LEU B CD1 1 
ATOM   3562 C CD2 . LEU B 2 45  ? 176.940 150.896 199.802 1.00 18.19 ? 45  LEU B CD2 1 
ATOM   3563 N N   . LYS B 2 46  ? 181.522 153.428 200.741 1.00 14.58 ? 46  LYS B N   1 
ATOM   3564 C CA  . LYS B 2 46  ? 181.869 154.724 201.312 1.00 14.58 ? 46  LYS B CA  1 
ATOM   3565 C C   . LYS B 2 46  ? 182.728 155.528 200.348 1.00 14.58 ? 46  LYS B C   1 
ATOM   3566 O O   . LYS B 2 46  ? 182.420 156.685 200.044 1.00 14.58 ? 46  LYS B O   1 
ATOM   3567 C CB  . LYS B 2 46  ? 182.593 154.558 202.645 1.00 14.58 ? 46  LYS B CB  1 
ATOM   3568 C CG  . LYS B 2 46  ? 183.396 155.795 203.024 1.00 14.58 ? 46  LYS B CG  1 
ATOM   3569 C CD  . LYS B 2 46  ? 184.459 155.516 204.065 1.00 14.58 ? 46  LYS B CD  1 
ATOM   3570 C CE  . LYS B 2 46  ? 183.870 154.826 205.279 1.00 14.58 ? 46  LYS B CE  1 
ATOM   3571 N NZ  . LYS B 2 46  ? 184.797 154.869 206.441 1.00 14.58 ? 46  LYS B NZ  1 
ATOM   3572 N N   . ALA B 2 47  ? 183.803 154.923 199.835 1.00 17.25 ? 47  ALA B N   1 
ATOM   3573 C CA  . ALA B 2 47  ? 184.738 155.652 198.985 1.00 17.25 ? 47  ALA B CA  1 
ATOM   3574 C C   . ALA B 2 47  ? 184.152 156.026 197.634 1.00 17.25 ? 47  ALA B C   1 
ATOM   3575 O O   . ALA B 2 47  ? 184.729 156.872 196.947 1.00 17.25 ? 47  ALA B O   1 
ATOM   3576 C CB  . ALA B 2 47  ? 186.012 154.835 198.780 1.00 17.25 ? 47  ALA B CB  1 
ATOM   3577 N N   . HIS B 2 48  ? 183.040 155.421 197.229 1.00 17.62 ? 48  HIS B N   1 
ATOM   3578 C CA  . HIS B 2 48  ? 182.364 155.836 196.012 1.00 17.62 ? 48  HIS B CA  1 
ATOM   3579 C C   . HIS B 2 48  ? 181.257 156.840 196.277 1.00 17.62 ? 48  HIS B C   1 
ATOM   3580 O O   . HIS B 2 48  ? 180.986 157.688 195.423 1.00 17.62 ? 48  HIS B O   1 
ATOM   3581 C CB  . HIS B 2 48  ? 181.781 154.625 195.289 1.00 17.62 ? 48  HIS B CB  1 
ATOM   3582 C CG  . HIS B 2 48  ? 181.027 154.970 194.044 1.00 17.62 ? 48  HIS B CG  1 
ATOM   3583 N ND1 . HIS B 2 48  ? 181.624 155.570 192.958 1.00 17.62 ? 48  HIS B ND1 1 
ATOM   3584 C CD2 . HIS B 2 48  ? 179.727 154.797 193.712 1.00 17.62 ? 48  HIS B CD2 1 
ATOM   3585 C CE1 . HIS B 2 48  ? 180.724 155.751 192.008 1.00 17.62 ? 48  HIS B CE1 1 
ATOM   3586 N NE2 . HIS B 2 48  ? 179.564 155.293 192.442 1.00 17.62 ? 48  HIS B NE2 1 
ATOM   3587 N N   . LEU B 2 49  ? 180.593 156.756 197.431 1.00 16.01 ? 49  LEU B N   1 
ATOM   3588 C CA  . LEU B 2 49  ? 179.623 157.782 197.794 1.00 16.01 ? 49  LEU B CA  1 
ATOM   3589 C C   . LEU B 2 49  ? 180.305 159.052 198.287 1.00 16.01 ? 49  LEU B C   1 
ATOM   3590 O O   . LEU B 2 49  ? 179.757 160.146 198.126 1.00 16.01 ? 49  LEU B O   1 
ATOM   3591 C CB  . LEU B 2 49  ? 178.657 157.236 198.842 1.00 16.01 ? 49  LEU B CB  1 
ATOM   3592 C CG  . LEU B 2 49  ? 177.545 156.370 198.252 1.00 16.01 ? 49  LEU B CG  1 
ATOM   3593 C CD1 . LEU B 2 49  ? 176.738 155.704 199.343 1.00 16.01 ? 49  LEU B CD1 1 
ATOM   3594 C CD2 . LEU B 2 49  ? 176.653 157.197 197.350 1.00 16.01 ? 49  LEU B CD2 1 
ATOM   3595 N N   . MET B 2 50  ? 181.493 158.927 198.882 1.00 15.96 ? 50  MET B N   1 
ATOM   3596 C CA  . MET B 2 50  ? 182.323 160.076 199.220 1.00 15.96 ? 50  MET B CA  1 
ATOM   3597 C C   . MET B 2 50  ? 182.708 160.889 197.994 1.00 15.96 ? 50  MET B C   1 
ATOM   3598 O O   . MET B 2 50  ? 183.001 162.081 198.122 1.00 15.96 ? 50  MET B O   1 
ATOM   3599 C CB  . MET B 2 50  ? 183.601 159.597 199.913 1.00 15.96 ? 50  MET B CB  1 
ATOM   3600 C CG  . MET B 2 50  ? 184.562 160.682 200.356 1.00 15.96 ? 50  MET B CG  1 
ATOM   3601 S SD  . MET B 2 50  ? 185.644 160.181 201.707 1.00 15.96 ? 50  MET B SD  1 
ATOM   3602 C CE  . MET B 2 50  ? 184.515 160.144 203.083 1.00 15.96 ? 50  MET B CE  1 
ATOM   3603 N N   . LYS B 2 51  ? 182.692 160.278 196.813 1.00 16.00 ? 51  LYS B N   1 
ATOM   3604 C CA  . LYS B 2 51  ? 183.203 160.875 195.589 1.00 16.00 ? 51  LYS B CA  1 
ATOM   3605 C C   . LYS B 2 51  ? 182.093 161.385 194.682 1.00 16.00 ? 51  LYS B C   1 
ATOM   3606 O O   . LYS B 2 51  ? 182.302 161.506 193.473 1.00 16.00 ? 51  LYS B O   1 
ATOM   3607 C CB  . LYS B 2 51  ? 184.064 159.854 194.847 1.00 16.00 ? 51  LYS B CB  1 
ATOM   3608 C CG  . LYS B 2 51  ? 185.245 160.420 194.104 1.00 16.00 ? 51  LYS B CG  1 
ATOM   3609 C CD  . LYS B 2 51  ? 185.981 159.309 193.375 1.00 16.00 ? 51  LYS B CD  1 
ATOM   3610 C CE  . LYS B 2 51  ? 186.463 158.244 194.340 1.00 16.00 ? 51  LYS B CE  1 
ATOM   3611 N NZ  . LYS B 2 51  ? 187.255 158.831 195.452 1.00 16.00 ? 51  LYS B NZ  1 
ATOM   3612 N N   . GLU B 2 52  ? 180.917 161.674 195.239 1.00 19.15 ? 52  GLU B N   1 
ATOM   3613 C CA  . GLU B 2 52  ? 179.749 162.081 194.459 1.00 19.15 ? 52  GLU B CA  1 
ATOM   3614 C C   . GLU B 2 52  ? 179.372 161.049 193.407 1.00 19.15 ? 52  GLU B C   1 
ATOM   3615 O O   . GLU B 2 52  ? 178.906 161.397 192.323 1.00 19.15 ? 52  GLU B O   1 
ATOM   3616 C CB  . GLU B 2 52  ? 179.956 163.442 193.798 1.00 19.15 ? 52  GLU B CB  1 
ATOM   3617 C CG  . GLU B 2 52  ? 179.995 164.597 194.755 1.00 19.15 ? 52  GLU B CG  1 
ATOM   3618 C CD  . GLU B 2 52  ? 178.634 165.232 194.889 1.00 19.15 ? 52  GLU B CD  1 
ATOM   3619 O OE1 . GLU B 2 52  ? 178.565 166.446 195.149 1.00 19.15 ? 52  GLU B OE1 1 
ATOM   3620 O OE2 . GLU B 2 52  ? 177.627 164.514 194.717 1.00 19.15 ? 52  GLU B OE2 1 
ATOM   3621 N N   . GLY B 2 53  ? 179.550 159.776 193.718 1.00 23.66 ? 53  GLY B N   1 
ATOM   3622 C CA  . GLY B 2 53  ? 179.180 158.712 192.808 1.00 23.66 ? 53  GLY B CA  1 
ATOM   3623 C C   . GLY B 2 53  ? 177.682 158.524 192.739 1.00 23.66 ? 53  GLY B C   1 
ATOM   3624 O O   . GLY B 2 53  ? 176.899 159.432 193.036 1.00 23.66 ? 53  GLY B O   1 
ATOM   3625 N N   . ARG B 2 54  ? 177.276 157.326 192.338 1.00 30.59 ? 54  ARG B N   1 
ATOM   3626 C CA  . ARG B 2 54  ? 175.864 156.990 192.250 1.00 30.59 ? 54  ARG B CA  1 
ATOM   3627 C C   . ARG B 2 54  ? 175.747 155.475 192.184 1.00 30.59 ? 54  ARG B C   1 
ATOM   3628 O O   . ARG B 2 54  ? 176.744 154.760 192.073 1.00 30.59 ? 54  ARG B O   1 
ATOM   3629 C CB  . ARG B 2 54  ? 175.208 157.665 191.043 1.00 30.59 ? 54  ARG B CB  1 
ATOM   3630 C CG  . ARG B 2 54  ? 173.769 158.079 191.270 1.00 30.59 ? 54  ARG B CG  1 
ATOM   3631 C CD  . ARG B 2 54  ? 173.425 159.300 190.436 1.00 30.59 ? 54  ARG B CD  1 
ATOM   3632 N NE  . ARG B 2 54  ? 173.921 160.526 191.056 1.00 30.59 ? 54  ARG B NE  1 
ATOM   3633 C CZ  . ARG B 2 54  ? 173.755 161.745 190.553 1.00 30.59 ? 54  ARG B CZ  1 
ATOM   3634 N NH1 . ARG B 2 54  ? 173.104 161.912 189.409 1.00 30.59 ? 54  ARG B NH1 1 
ATOM   3635 N NH2 . ARG B 2 54  ? 174.244 162.799 191.191 1.00 30.59 ? 54  ARG B NH2 1 
ATOM   3636 N N   . LEU B 2 55  ? 174.513 154.993 192.269 1.00 33.36 ? 55  LEU B N   1 
ATOM   3637 C CA  . LEU B 2 55  ? 174.228 153.569 192.257 1.00 33.36 ? 55  LEU B CA  1 
ATOM   3638 C C   . LEU B 2 55  ? 173.097 153.292 191.279 1.00 33.36 ? 55  LEU B C   1 
ATOM   3639 O O   . LEU B 2 55  ? 172.298 154.174 190.957 1.00 33.36 ? 55  LEU B O   1 
ATOM   3640 C CB  . LEU B 2 55  ? 173.850 153.058 193.654 1.00 33.36 ? 55  LEU B CB  1 
ATOM   3641 C CG  . LEU B 2 55  ? 174.930 152.342 194.463 1.00 33.36 ? 55  LEU B CG  1 
ATOM   3642 C CD1 . LEU B 2 55  ? 176.015 153.309 194.883 1.00 33.36 ? 55  LEU B CD1 1 
ATOM   3643 C CD2 . LEU B 2 55  ? 174.328 151.660 195.674 1.00 33.36 ? 55  LEU B CD2 1 
ATOM   3644 N N   . GLU B 2 56  ? 173.038 152.054 190.800 1.00 40.52 ? 56  GLU B N   1 
ATOM   3645 C CA  . GLU B 2 56  ? 171.931 151.650 189.950 1.00 40.52 ? 56  GLU B CA  1 
ATOM   3646 C C   . GLU B 2 56  ? 170.641 151.610 190.762 1.00 40.52 ? 56  GLU B C   1 
ATOM   3647 O O   . GLU B 2 56  ? 170.652 151.581 191.994 1.00 40.52 ? 56  GLU B O   1 
ATOM   3648 C CB  . GLU B 2 56  ? 172.206 150.286 189.320 1.00 40.52 ? 56  GLU B CB  1 
ATOM   3649 N N   . GLU B 2 57  ? 169.511 151.629 190.057 1.00 42.96 ? 57  GLU B N   1 
ATOM   3650 C CA  . GLU B 2 57  ? 168.232 151.658 190.757 1.00 42.96 ? 57  GLU B CA  1 
ATOM   3651 C C   . GLU B 2 57  ? 167.922 150.317 191.414 1.00 42.96 ? 57  GLU B C   1 
ATOM   3652 O O   . GLU B 2 57  ? 167.505 150.273 192.579 1.00 42.96 ? 57  GLU B O   1 
ATOM   3653 C CB  . GLU B 2 57  ? 167.117 152.061 189.796 1.00 42.96 ? 57  GLU B CB  1 
ATOM   3654 C CG  . GLU B 2 57  ? 165.854 152.530 190.492 1.00 42.96 ? 57  GLU B CG  1 
ATOM   3655 C CD  . GLU B 2 57  ? 164.700 152.732 189.533 1.00 42.96 ? 57  GLU B CD  1 
ATOM   3656 O OE1 . GLU B 2 57  ? 163.576 152.291 189.850 1.00 42.96 ? 57  GLU B OE1 1 
ATOM   3657 O OE2 . GLU B 2 57  ? 164.914 153.343 188.465 1.00 42.96 ? 57  GLU B OE2 1 
ATOM   3658 N N   . SER B 2 58  ? 168.132 149.213 190.693 1.00 37.75 ? 58  SER B N   1 
ATOM   3659 C CA  . SER B 2 58  ? 167.756 147.906 191.223 1.00 37.75 ? 58  SER B CA  1 
ATOM   3660 C C   . SER B 2 58  ? 168.575 147.543 192.456 1.00 37.75 ? 58  SER B C   1 
ATOM   3661 O O   . SER B 2 58  ? 168.042 146.972 193.416 1.00 37.75 ? 58  SER B O   1 
ATOM   3662 C CB  . SER B 2 58  ? 167.908 146.838 190.143 1.00 37.75 ? 58  SER B CB  1 
ATOM   3663 O OG  . SER B 2 58  ? 167.476 145.576 190.621 1.00 37.75 ? 58  SER B OG  1 
ATOM   3664 N N   . VAL B 2 59  ? 169.869 147.865 192.457 1.00 35.15 ? 59  VAL B N   1 
ATOM   3665 C CA  . VAL B 2 59  ? 170.688 147.578 193.629 1.00 35.15 ? 59  VAL B CA  1 
ATOM   3666 C C   . VAL B 2 59  ? 170.235 148.418 194.823 1.00 35.15 ? 59  VAL B C   1 
ATOM   3667 O O   . VAL B 2 59  ? 170.256 147.951 195.969 1.00 35.15 ? 59  VAL B O   1 
ATOM   3668 C CB  . VAL B 2 59  ? 172.180 147.777 193.302 1.00 35.15 ? 59  VAL B CB  1 
ATOM   3669 C CG1 . VAL B 2 59  ? 172.473 149.214 192.932 1.00 35.15 ? 59  VAL B CG1 1 
ATOM   3670 C CG2 . VAL B 2 59  ? 173.036 147.351 194.477 1.00 35.15 ? 59  VAL B CG2 1 
ATOM   3671 N N   . ALA B 2 60  ? 169.809 149.661 194.578 1.00 30.45 ? 60  ALA B N   1 
ATOM   3672 C CA  . ALA B 2 60  ? 169.284 150.485 195.662 1.00 30.45 ? 60  ALA B CA  1 
ATOM   3673 C C   . ALA B 2 60  ? 168.015 149.882 196.247 1.00 30.45 ? 60  ALA B C   1 
ATOM   3674 O O   . ALA B 2 60  ? 167.844 149.836 197.473 1.00 30.45 ? 60  ALA B O   1 
ATOM   3675 C CB  . ALA B 2 60  ? 169.022 151.904 195.164 1.00 30.45 ? 60  ALA B CB  1 
ATOM   3676 N N   . LEU B 2 61  ? 167.112 149.412 195.383 1.00 30.70 ? 61  LEU B N   1 
ATOM   3677 C CA  . LEU B 2 61  ? 165.919 148.727 195.871 1.00 30.70 ? 61  LEU B CA  1 
ATOM   3678 C C   . LEU B 2 61  ? 166.285 147.497 196.689 1.00 30.70 ? 61  LEU B C   1 
ATOM   3679 O O   . LEU B 2 61  ? 165.670 147.226 197.726 1.00 30.70 ? 61  LEU B O   1 
ATOM   3680 C CB  . LEU B 2 61  ? 165.008 148.337 194.707 1.00 30.70 ? 61  LEU B CB  1 
ATOM   3681 C CG  . LEU B 2 61  ? 164.008 149.363 194.170 1.00 30.70 ? 61  LEU B CG  1 
ATOM   3682 C CD1 . LEU B 2 61  ? 163.010 149.682 195.258 1.00 30.70 ? 61  LEU B CD1 1 
ATOM   3683 C CD2 . LEU B 2 61  ? 164.666 150.632 193.673 1.00 30.70 ? 61  LEU B CD2 1 
ATOM   3684 N N   . ARG B 2 62  ? 167.287 146.742 196.237 1.00 34.19 ? 62  ARG B N   1 
ATOM   3685 C CA  . ARG B 2 62  ? 167.708 145.553 196.971 1.00 34.19 ? 62  ARG B CA  1 
ATOM   3686 C C   . ARG B 2 62  ? 168.231 145.916 198.357 1.00 34.19 ? 62  ARG B C   1 
ATOM   3687 O O   . ARG B 2 62  ? 167.868 145.282 199.358 1.00 34.19 ? 62  ARG B O   1 
ATOM   3688 C CB  . ARG B 2 62  ? 168.766 144.800 196.166 1.00 34.19 ? 62  ARG B CB  1 
ATOM   3689 C CG  . ARG B 2 62  ? 169.328 143.577 196.854 1.00 34.19 ? 62  ARG B CG  1 
ATOM   3690 C CD  . ARG B 2 62  ? 170.287 142.834 195.940 1.00 34.19 ? 62  ARG B CD  1 
ATOM   3691 N NE  . ARG B 2 62  ? 171.085 141.855 196.671 1.00 34.19 ? 62  ARG B NE  1 
ATOM   3692 C CZ  . ARG B 2 62  ? 172.117 141.196 196.156 1.00 34.19 ? 62  ARG B CZ  1 
ATOM   3693 N NH1 . ARG B 2 62  ? 172.785 140.323 196.898 1.00 34.19 ? 62  ARG B NH1 1 
ATOM   3694 N NH2 . ARG B 2 62  ? 172.482 141.409 194.900 1.00 34.19 ? 62  ARG B NH2 1 
ATOM   3695 N N   . ILE B 2 63  ? 169.070 146.954 198.436 1.00 26.96 ? 63  ILE B N   1 
ATOM   3696 C CA  . ILE B 2 63  ? 169.624 147.377 199.723 1.00 26.96 ? 63  ILE B CA  1 
ATOM   3697 C C   . ILE B 2 63  ? 168.509 147.790 200.673 1.00 26.96 ? 63  ILE B C   1 
ATOM   3698 O O   . ILE B 2 63  ? 168.453 147.349 201.828 1.00 26.96 ? 63  ILE B O   1 
ATOM   3699 C CB  . ILE B 2 63  ? 170.630 148.524 199.531 1.00 26.96 ? 63  ILE B CB  1 
ATOM   3700 C CG1 . ILE B 2 63  ? 171.892 148.037 198.830 1.00 26.96 ? 63  ILE B CG1 1 
ATOM   3701 C CG2 . ILE B 2 63  ? 170.983 149.134 200.866 1.00 26.96 ? 63  ILE B CG2 1 
ATOM   3702 C CD1 . ILE B 2 63  ? 173.032 149.030 198.896 1.00 26.96 ? 63  ILE B CD1 1 
ATOM   3703 N N   . ILE B 2 64  ? 167.606 148.647 200.198 1.00 24.68 ? 64  ILE B N   1 
ATOM   3704 C CA  . ILE B 2 64  ? 166.561 149.170 201.070 1.00 24.68 ? 64  ILE B CA  1 
ATOM   3705 C C   . ILE B 2 64  ? 165.622 148.056 201.520 1.00 24.68 ? 64  ILE B C   1 
ATOM   3706 O O   . ILE B 2 64  ? 165.208 148.010 202.685 1.00 24.68 ? 64  ILE B O   1 
ATOM   3707 C CB  . ILE B 2 64  ? 165.810 150.312 200.365 1.00 24.68 ? 64  ILE B CB  1 
ATOM   3708 C CG1 . ILE B 2 64  ? 166.696 151.555 200.311 1.00 24.68 ? 64  ILE B CG1 1 
ATOM   3709 C CG2 . ILE B 2 64  ? 164.513 150.619 201.076 1.00 24.68 ? 64  ILE B CG2 1 
ATOM   3710 C CD1 . ILE B 2 64  ? 166.178 152.633 199.405 1.00 24.68 ? 64  ILE B CD1 1 
ATOM   3711 N N   . THR B 2 65  ? 165.276 147.133 200.617 1.00 27.41 ? 65  THR B N   1 
ATOM   3712 C CA  . THR B 2 65  ? 164.381 146.044 200.993 1.00 27.41 ? 65  THR B CA  1 
ATOM   3713 C C   . THR B 2 65  ? 165.035 145.103 201.999 1.00 27.41 ? 65  THR B C   1 
ATOM   3714 O O   . THR B 2 65  ? 164.374 144.635 202.935 1.00 27.41 ? 65  THR B O   1 
ATOM   3715 C CB  . THR B 2 65  ? 163.935 145.278 199.751 1.00 27.41 ? 65  THR B CB  1 
ATOM   3716 O OG1 . THR B 2 65  ? 163.435 146.200 198.776 1.00 27.41 ? 65  THR B OG1 1 
ATOM   3717 C CG2 . THR B 2 65  ? 162.837 144.294 200.109 1.00 27.41 ? 65  THR B CG2 1 
ATOM   3718 N N   . GLU B 2 66  ? 166.328 144.812 201.832 1.00 22.88 ? 66  GLU B N   1 
ATOM   3719 C CA  . GLU B 2 66  ? 167.019 143.988 202.819 1.00 22.88 ? 66  GLU B CA  1 
ATOM   3720 C C   . GLU B 2 66  ? 167.064 144.678 204.180 1.00 22.88 ? 66  GLU B C   1 
ATOM   3721 O O   . GLU B 2 66  ? 166.869 144.035 205.224 1.00 22.88 ? 66  GLU B O   1 
ATOM   3722 C CB  . GLU B 2 66  ? 168.430 143.663 202.332 1.00 22.88 ? 66  GLU B CB  1 
ATOM   3723 C CG  . GLU B 2 66  ? 168.492 142.543 201.308 1.00 22.88 ? 66  GLU B CG  1 
ATOM   3724 C CD  . GLU B 2 66  ? 169.881 141.941 201.183 1.00 22.88 ? 66  GLU B CD  1 
ATOM   3725 O OE1 . GLU B 2 66  ? 170.852 142.711 201.035 1.00 22.88 ? 66  GLU B OE1 1 
ATOM   3726 O OE2 . GLU B 2 66  ? 170.003 140.699 201.231 1.00 22.88 ? 66  GLU B OE2 1 
ATOM   3727 N N   . GLY B 2 67  ? 167.326 145.987 204.191 1.00 19.42 ? 67  GLY B N   1 
ATOM   3728 C CA  . GLY B 2 67  ? 167.312 146.720 205.447 1.00 19.42 ? 67  GLY B CA  1 
ATOM   3729 C C   . GLY B 2 67  ? 165.955 146.682 206.121 1.00 19.42 ? 67  GLY B C   1 
ATOM   3730 O O   . GLY B 2 67  ? 165.859 146.516 207.338 1.00 19.42 ? 67  GLY B O   1 
ATOM   3731 N N   . ALA B 2 68  ? 164.888 146.826 205.335 1.00 18.93 ? 68  ALA B N   1 
ATOM   3732 C CA  . ALA B 2 68  ? 163.543 146.729 205.889 1.00 18.93 ? 68  ALA B CA  1 
ATOM   3733 C C   . ALA B 2 68  ? 163.283 145.345 206.466 1.00 18.93 ? 68  ALA B C   1 
ATOM   3734 O O   . ALA B 2 68  ? 162.664 145.211 207.528 1.00 18.93 ? 68  ALA B O   1 
ATOM   3735 C CB  . ALA B 2 68  ? 162.508 147.059 204.816 1.00 18.93 ? 68  ALA B CB  1 
ATOM   3736 N N   . SER B 2 69  ? 163.736 144.301 205.770 1.00 18.31 ? 69  SER B N   1 
ATOM   3737 C CA  . SER B 2 69  ? 163.519 142.944 206.258 1.00 18.31 ? 69  SER B CA  1 
ATOM   3738 C C   . SER B 2 69  ? 164.231 142.710 207.582 1.00 18.31 ? 69  SER B C   1 
ATOM   3739 O O   . SER B 2 69  ? 163.699 142.030 208.465 1.00 18.31 ? 69  SER B O   1 
ATOM   3740 C CB  . SER B 2 69  ? 163.978 141.928 205.215 1.00 18.31 ? 69  SER B CB  1 
ATOM   3741 O OG  . SER B 2 69  ? 163.124 141.938 204.086 1.00 18.31 ? 69  SER B OG  1 
ATOM   3742 N N   . ILE B 2 70  ? 165.443 143.245 207.738 1.00 15.48 ? 70  ILE B N   1 
ATOM   3743 C CA  . ILE B 2 70  ? 166.125 143.076 209.022 1.00 15.48 ? 70  ILE B CA  1 
ATOM   3744 C C   . ILE B 2 70  ? 165.456 143.910 210.109 1.00 15.48 ? 70  ILE B C   1 
ATOM   3745 O O   . ILE B 2 70  ? 165.315 143.459 211.252 1.00 15.48 ? 70  ILE B O   1 
ATOM   3746 C CB  . ILE B 2 70  ? 167.627 143.389 208.911 1.00 15.48 ? 70  ILE B CB  1 
ATOM   3747 C CG1 . ILE B 2 70  ? 168.341 142.271 208.159 1.00 15.48 ? 70  ILE B CG1 1 
ATOM   3748 C CG2 . ILE B 2 70  ? 168.243 143.539 210.283 1.00 15.48 ? 70  ILE B CG2 1 
ATOM   3749 C CD1 . ILE B 2 70  ? 169.824 142.475 208.035 1.00 15.48 ? 70  ILE B CD1 1 
ATOM   3750 N N   . LEU B 2 71  ? 165.029 145.133 209.781 1.00 14.57 ? 71  LEU B N   1 
ATOM   3751 C CA  . LEU B 2 71  ? 164.462 146.013 210.802 1.00 14.57 ? 71  LEU B CA  1 
ATOM   3752 C C   . LEU B 2 71  ? 163.105 145.527 211.295 1.00 14.57 ? 71  LEU B C   1 
ATOM   3753 O O   . LEU B 2 71  ? 162.786 145.696 212.475 1.00 14.57 ? 71  LEU B O   1 
ATOM   3754 C CB  . LEU B 2 71  ? 164.343 147.437 210.265 1.00 14.57 ? 71  LEU B CB  1 
ATOM   3755 C CG  . LEU B 2 71  ? 165.607 148.285 210.360 1.00 14.57 ? 71  LEU B CG  1 
ATOM   3756 C CD1 . LEU B 2 71  ? 165.548 149.434 209.380 1.00 14.57 ? 71  LEU B CD1 1 
ATOM   3757 C CD2 . LEU B 2 71  ? 165.777 148.790 211.769 1.00 14.57 ? 71  LEU B CD2 1 
ATOM   3758 N N   . ARG B 2 72  ? 162.297 144.929 210.417 1.00 19.48 ? 72  ARG B N   1 
ATOM   3759 C CA  . ARG B 2 72  ? 160.949 144.526 210.807 1.00 19.48 ? 72  ARG B CA  1 
ATOM   3760 C C   . ARG B 2 72  ? 160.970 143.451 211.887 1.00 19.48 ? 72  ARG B C   1 
ATOM   3761 O O   . ARG B 2 72  ? 160.111 143.439 212.776 1.00 19.48 ? 72  ARG B O   1 
ATOM   3762 C CB  . ARG B 2 72  ? 160.174 144.041 209.585 1.00 19.48 ? 72  ARG B CB  1 
ATOM   3763 C CG  . ARG B 2 72  ? 158.779 143.532 209.894 1.00 19.48 ? 72  ARG B CG  1 
ATOM   3764 C CD  . ARG B 2 72  ? 157.837 143.724 208.714 1.00 19.48 ? 72  ARG B CD  1 
ATOM   3765 N NE  . ARG B 2 72  ? 158.494 143.501 207.429 1.00 19.48 ? 72  ARG B NE  1 
ATOM   3766 C CZ  . ARG B 2 72  ? 158.863 142.309 206.968 1.00 19.48 ? 72  ARG B CZ  1 
ATOM   3767 N NH1 . ARG B 2 72  ? 158.645 141.216 207.685 1.00 19.48 ? 72  ARG B NH1 1 
ATOM   3768 N NH2 . ARG B 2 72  ? 159.456 142.210 205.787 1.00 19.48 ? 72  ARG B NH2 1 
ATOM   3769 N N   . GLN B 2 73  ? 161.932 142.529 211.825 1.00 17.25 ? 73  GLN B N   1 
ATOM   3770 C CA  . GLN B 2 73  ? 162.002 141.474 212.830 1.00 17.25 ? 73  GLN B CA  1 
ATOM   3771 C C   . GLN B 2 73  ? 162.437 141.994 214.192 1.00 17.25 ? 73  GLN B C   1 
ATOM   3772 O O   . GLN B 2 73  ? 162.278 141.283 215.189 1.00 17.25 ? 73  GLN B O   1 
ATOM   3773 C CB  . GLN B 2 73  ? 162.960 140.372 212.383 1.00 17.25 ? 73  GLN B CB  1 
ATOM   3774 C CG  . GLN B 2 73  ? 162.897 140.054 210.908 1.00 17.25 ? 73  GLN B CG  1 
ATOM   3775 C CD  . GLN B 2 73  ? 164.106 139.279 210.434 1.00 17.25 ? 73  GLN B CD  1 
ATOM   3776 O OE1 . GLN B 2 73  ? 164.691 138.499 211.184 1.00 17.25 ? 73  GLN B OE1 1 
ATOM   3777 N NE2 . GLN B 2 73  ? 164.489 139.492 209.182 1.00 17.25 ? 73  GLN B NE2 1 
ATOM   3778 N N   . GLU B 2 74  ? 162.988 143.202 214.257 1.00 15.71 ? 74  GLU B N   1 
ATOM   3779 C CA  . GLU B 2 74  ? 163.451 143.744 215.525 1.00 15.71 ? 74  GLU B CA  1 
ATOM   3780 C C   . GLU B 2 74  ? 162.265 144.061 216.428 1.00 15.71 ? 74  GLU B C   1 
ATOM   3781 O O   . GLU B 2 74  ? 161.139 144.257 215.967 1.00 15.71 ? 74  GLU B O   1 
ATOM   3782 C CB  . GLU B 2 74  ? 164.288 145.002 215.297 1.00 15.71 ? 74  GLU B CB  1 
ATOM   3783 C CG  . GLU B 2 74  ? 165.724 144.738 214.844 1.00 15.71 ? 74  GLU B CG  1 
ATOM   3784 C CD  . GLU B 2 74  ? 166.756 144.942 215.945 1.00 15.71 ? 74  GLU B CD  1 
ATOM   3785 O OE1 . GLU B 2 74  ? 166.378 144.920 217.134 1.00 15.71 ? 74  GLU B OE1 1 
ATOM   3786 O OE2 . GLU B 2 74  ? 167.946 145.136 215.619 1.00 15.71 ? 74  GLU B OE2 1 
ATOM   3787 N N   . LYS B 2 75  ? 162.530 144.109 217.729 1.00 10.55 ? 75  LYS B N   1 
ATOM   3788 C CA  . LYS B 2 75  ? 161.485 144.399 218.694 1.00 10.55 ? 75  LYS B CA  1 
ATOM   3789 C C   . LYS B 2 75  ? 160.970 145.824 218.505 1.00 10.55 ? 75  LYS B C   1 
ATOM   3790 O O   . LYS B 2 75  ? 161.446 146.583 217.660 1.00 10.55 ? 75  LYS B O   1 
ATOM   3791 C CB  . LYS B 2 75  ? 162.008 144.212 220.116 1.00 10.55 ? 75  LYS B CB  1 
ATOM   3792 C CG  . LYS B 2 75  ? 161.917 142.791 220.622 1.00 10.55 ? 75  LYS B CG  1 
ATOM   3793 C CD  . LYS B 2 75  ? 161.478 142.744 222.071 1.00 10.55 ? 75  LYS B CD  1 
ATOM   3794 C CE  . LYS B 2 75  ? 162.443 143.486 222.967 1.00 10.55 ? 75  LYS B CE  1 
ATOM   3795 N NZ  . LYS B 2 75  ? 162.090 143.316 224.401 1.00 10.55 ? 75  LYS B NZ  1 
ATOM   3796 N N   . ASN B 2 76  ? 159.970 146.182 219.306 1.00 11.09 ? 76  ASN B N   1 
ATOM   3797 C CA  . ASN B 2 76  ? 159.466 147.549 219.310 1.00 11.09 ? 76  ASN B CA  1 
ATOM   3798 C C   . ASN B 2 76  ? 160.135 148.408 220.369 1.00 11.09 ? 76  ASN B C   1 
ATOM   3799 O O   . ASN B 2 76  ? 160.237 149.626 220.195 1.00 11.09 ? 76  ASN B O   1 
ATOM   3800 C CB  . ASN B 2 76  ? 157.956 147.556 219.529 1.00 11.09 ? 76  ASN B CB  1 
ATOM   3801 C CG  . ASN B 2 76  ? 157.365 148.931 219.397 1.00 11.09 ? 76  ASN B CG  1 
ATOM   3802 O OD1 . ASN B 2 76  ? 157.391 149.722 220.334 1.00 11.09 ? 76  ASN B OD1 1 
ATOM   3803 N ND2 . ASN B 2 76  ? 156.832 149.232 218.223 1.00 11.09 ? 76  ASN B ND2 1 
ATOM   3804 N N   . LEU B 2 77  ? 160.586 147.800 221.459 1.00 10.88 ? 77  LEU B N   1 
ATOM   3805 C CA  . LEU B 2 77  ? 161.385 148.456 222.489 1.00 10.88 ? 77  LEU B CA  1 
ATOM   3806 C C   . LEU B 2 77  ? 162.721 147.725 222.536 1.00 10.88 ? 77  LEU B C   1 
ATOM   3807 O O   . LEU B 2 77  ? 162.839 146.681 223.183 1.00 10.88 ? 77  LEU B O   1 
ATOM   3808 C CB  . LEU B 2 77  ? 160.662 148.431 223.833 1.00 10.88 ? 77  LEU B CB  1 
ATOM   3809 C CG  . LEU B 2 77  ? 161.225 149.203 225.025 1.00 10.88 ? 77  LEU B CG  1 
ATOM   3810 C CD1 . LEU B 2 77  ? 160.112 149.580 225.960 1.00 10.88 ? 77  LEU B CD1 1 
ATOM   3811 C CD2 . LEU B 2 77  ? 162.218 148.364 225.777 1.00 10.88 ? 77  LEU B CD2 1 
ATOM   3812 N N   . LEU B 2 78  ? 163.720 148.263 221.836 1.00 10.84 ? 78  LEU B N   1 
ATOM   3813 C CA  . LEU B 2 78  ? 165.013 147.599 221.746 1.00 10.84 ? 78  LEU B CA  1 
ATOM   3814 C C   . LEU B 2 78  ? 165.657 147.490 223.117 1.00 10.84 ? 78  LEU B C   1 
ATOM   3815 O O   . LEU B 2 78  ? 165.617 148.426 223.917 1.00 10.84 ? 78  LEU B O   1 
ATOM   3816 C CB  . LEU B 2 78  ? 165.950 148.362 220.815 1.00 10.84 ? 78  LEU B CB  1 
ATOM   3817 C CG  . LEU B 2 78  ? 165.457 148.755 219.433 1.00 10.84 ? 78  LEU B CG  1 
ATOM   3818 C CD1 . LEU B 2 78  ? 166.366 149.824 218.878 1.00 10.84 ? 78  LEU B CD1 1 
ATOM   3819 C CD2 . LEU B 2 78  ? 165.436 147.555 218.528 1.00 10.84 ? 78  LEU B CD2 1 
ATOM   3820 N N   . ASP B 2 79  ? 166.263 146.345 223.382 1.00 12.77 ? 79  ASP B N   1 
ATOM   3821 C CA  . ASP B 2 79  ? 166.991 146.117 224.621 1.00 12.77 ? 79  ASP B CA  1 
ATOM   3822 C C   . ASP B 2 79  ? 168.465 146.039 224.241 1.00 12.77 ? 79  ASP B C   1 
ATOM   3823 O O   . ASP B 2 79  ? 168.891 145.104 223.559 1.00 12.77 ? 79  ASP B O   1 
ATOM   3824 C CB  . ASP B 2 79  ? 166.496 144.855 225.314 1.00 12.77 ? 79  ASP B CB  1 
ATOM   3825 C CG  . ASP B 2 79  ? 167.069 144.692 226.700 1.00 12.77 ? 79  ASP B CG  1 
ATOM   3826 O OD1 . ASP B 2 79  ? 167.880 145.543 227.117 1.00 12.77 ? 79  ASP B OD1 1 
ATOM   3827 O OD2 . ASP B 2 79  ? 166.696 143.717 227.381 1.00 12.77 ? 79  ASP B OD2 1 
ATOM   3828 N N   . ILE B 2 80  ? 169.235 147.031 224.676 1.00 11.81 ? 80  ILE B N   1 
ATOM   3829 C CA  . ILE B 2 80  ? 170.615 147.195 224.257 1.00 11.81 ? 80  ILE B CA  1 
ATOM   3830 C C   . ILE B 2 80  ? 171.533 146.896 225.432 1.00 11.81 ? 80  ILE B C   1 
ATOM   3831 O O   . ILE B 2 80  ? 171.165 147.045 226.599 1.00 11.81 ? 80  ILE B O   1 
ATOM   3832 C CB  . ILE B 2 80  ? 170.860 148.615 223.705 1.00 11.81 ? 80  ILE B CB  1 
ATOM   3833 C CG1 . ILE B 2 80  ? 169.780 148.981 222.700 1.00 11.81 ? 80  ILE B CG1 1 
ATOM   3834 C CG2 . ILE B 2 80  ? 172.189 148.705 223.020 1.00 11.81 ? 80  ILE B CG2 1 
ATOM   3835 C CD1 . ILE B 2 80  ? 170.016 150.297 222.038 1.00 11.81 ? 80  ILE B CD1 1 
ATOM   3836 N N   . ASP B 2 81  ? 172.751 146.462 225.122 1.00 19.66 ? 81  ASP B N   1 
ATOM   3837 C CA  . ASP B 2 81  ? 173.757 146.182 226.130 1.00 19.66 ? 81  ASP B CA  1 
ATOM   3838 C C   . ASP B 2 81  ? 174.505 147.481 226.441 1.00 19.66 ? 81  ASP B C   1 
ATOM   3839 O O   . ASP B 2 81  ? 174.232 148.533 225.861 1.00 19.66 ? 81  ASP B O   1 
ATOM   3840 C CB  . ASP B 2 81  ? 174.681 145.062 225.646 1.00 19.66 ? 81  ASP B CB  1 
ATOM   3841 C CG  . ASP B 2 81  ? 175.618 144.562 226.727 1.00 19.66 ? 81  ASP B CG  1 
ATOM   3842 O OD1 . ASP B 2 81  ? 175.576 145.104 227.851 1.00 19.66 ? 81  ASP B OD1 1 
ATOM   3843 O OD2 . ASP B 2 81  ? 176.396 143.623 226.456 1.00 19.66 ? 81  ASP B OD2 1 
ATOM   3844 N N   . ALA B 2 82  ? 175.465 147.411 227.369 1.00 16.29 ? 82  ALA B N   1 
ATOM   3845 C CA  . ALA B 2 82  ? 175.982 148.641 227.969 1.00 16.29 ? 82  ALA B CA  1 
ATOM   3846 C C   . ALA B 2 82  ? 176.878 149.447 227.035 1.00 16.29 ? 82  ALA B C   1 
ATOM   3847 O O   . ALA B 2 82  ? 176.500 150.579 226.687 1.00 16.29 ? 82  ALA B O   1 
ATOM   3848 C CB  . ALA B 2 82  ? 176.683 148.319 229.291 1.00 16.29 ? 82  ALA B CB  1 
ATOM   3849 N N   . PRO B 2 83  ? 178.044 148.951 226.575 1.00 15.21 ? 83  PRO B N   1 
ATOM   3850 C CA  . PRO B 2 83  ? 179.032 149.879 225.968 1.00 15.21 ? 83  PRO B CA  1 
ATOM   3851 C C   . PRO B 2 83  ? 178.604 150.436 224.615 1.00 15.21 ? 83  PRO B C   1 
ATOM   3852 O O   . PRO B 2 83  ? 179.063 150.014 223.553 1.00 15.21 ? 83  PRO B O   1 
ATOM   3853 C CB  . PRO B 2 83  ? 180.284 148.999 225.861 1.00 15.21 ? 83  PRO B CB  1 
ATOM   3854 C CG  . PRO B 2 83  ? 180.027 147.826 226.752 1.00 15.21 ? 83  PRO B CG  1 
ATOM   3855 C CD  . PRO B 2 83  ? 178.572 147.581 226.599 1.00 15.21 ? 83  PRO B CD  1 
ATOM   3856 N N   . VAL B 2 84  ? 177.716 151.425 224.639 1.00 19.71 ? 84  VAL B N   1 
ATOM   3857 C CA  . VAL B 2 84  ? 177.173 152.010 223.422 1.00 19.71 ? 84  VAL B CA  1 
ATOM   3858 C C   . VAL B 2 84  ? 177.754 153.401 223.217 1.00 19.71 ? 84  VAL B C   1 
ATOM   3859 O O   . VAL B 2 84  ? 178.406 153.973 224.093 1.00 19.71 ? 84  VAL B O   1 
ATOM   3860 C CB  . VAL B 2 84  ? 175.635 152.073 223.447 1.00 19.71 ? 84  VAL B CB  1 
ATOM   3861 C CG1 . VAL B 2 84  ? 175.056 150.701 223.287 1.00 19.71 ? 84  VAL B CG1 1 
ATOM   3862 C CG2 . VAL B 2 84  ? 175.159 152.696 224.731 1.00 19.71 ? 84  VAL B CG2 1 
ATOM   3863 N N   . THR B 2 85  ? 177.505 153.946 222.030 1.00 25.32 ? 85  THR B N   1 
ATOM   3864 C CA  . THR B 2 85  ? 177.913 155.294 221.643 1.00 25.32 ? 85  THR B CA  1 
ATOM   3865 C C   . THR B 2 85  ? 176.698 155.979 221.030 1.00 25.32 ? 85  THR B C   1 
ATOM   3866 O O   . THR B 2 85  ? 176.510 155.950 219.814 1.00 25.32 ? 85  THR B O   1 
ATOM   3867 C CB  . THR B 2 85  ? 179.073 155.248 220.668 1.00 25.32 ? 85  THR B CB  1 
ATOM   3868 O OG1 . THR B 2 85  ? 180.129 154.453 221.218 1.00 25.32 ? 85  THR B OG1 1 
ATOM   3869 C CG2 . THR B 2 85  ? 179.589 156.635 220.381 1.00 25.32 ? 85  THR B CG2 1 
ATOM   3870 N N   . VAL B 2 86  ? 175.875 156.602 221.875 1.00 21.39 ? 86  VAL B N   1 
ATOM   3871 C CA  . VAL B 2 86  ? 174.651 157.232 221.397 1.00 21.39 ? 86  VAL B CA  1 
ATOM   3872 C C   . VAL B 2 86  ? 174.990 158.394 220.472 1.00 21.39 ? 86  VAL B C   1 
ATOM   3873 O O   . VAL B 2 86  ? 176.020 159.057 220.631 1.00 21.39 ? 86  VAL B O   1 
ATOM   3874 C CB  . VAL B 2 86  ? 173.811 157.692 222.598 1.00 21.39 ? 86  VAL B CB  1 
ATOM   3875 C CG1 . VAL B 2 86  ? 172.430 158.088 222.159 1.00 21.39 ? 86  VAL B CG1 1 
ATOM   3876 C CG2 . VAL B 2 86  ? 173.740 156.593 223.633 1.00 21.39 ? 86  VAL B CG2 1 
ATOM   3877 N N   . CYS B 2 87  ? 174.130 158.641 219.488 1.00 21.39 ? 87  CYS B N   1 
ATOM   3878 C CA  . CYS B 2 87  ? 174.335 159.734 218.550 1.00 21.39 ? 87  CYS B CA  1 
ATOM   3879 C C   . CYS B 2 87  ? 173.007 160.416 218.266 1.00 21.39 ? 87  CYS B C   1 
ATOM   3880 O O   . CYS B 2 87  ? 171.939 159.829 218.433 1.00 21.39 ? 87  CYS B O   1 
ATOM   3881 C CB  . CYS B 2 87  ? 174.965 159.244 217.247 1.00 21.39 ? 87  CYS B CB  1 
ATOM   3882 S SG  . CYS B 2 87  ? 176.665 158.693 217.411 1.00 21.39 ? 87  CYS B SG  1 
ATOM   3883 N N   . GLY B 2 88  ? 173.081 161.666 217.825 1.00 21.29 ? 88  GLY B N   1 
ATOM   3884 C CA  . GLY B 2 88  ? 171.912 162.493 217.623 1.00 21.29 ? 88  GLY B CA  1 
ATOM   3885 C C   . GLY B 2 88  ? 171.400 162.463 216.199 1.00 21.29 ? 88  GLY B C   1 
ATOM   3886 O O   . GLY B 2 88  ? 171.629 161.514 215.443 1.00 21.29 ? 88  GLY B O   1 
ATOM   3887 N N   . ASP B 2 89  ? 170.691 163.527 215.828 1.00 9.43  ? 89  ASP B N   1 
ATOM   3888 C CA  . ASP B 2 89  ? 170.082 163.617 214.510 1.00 9.43  ? 89  ASP B CA  1 
ATOM   3889 C C   . ASP B 2 89  ? 171.052 164.221 213.507 1.00 9.43  ? 89  ASP B C   1 
ATOM   3890 O O   . ASP B 2 89  ? 171.726 165.210 213.795 1.00 9.43  ? 89  ASP B O   1 
ATOM   3891 C CB  . ASP B 2 89  ? 168.820 164.467 214.570 1.00 9.43  ? 89  ASP B CB  1 
ATOM   3892 C CG  . ASP B 2 89  ? 169.060 165.799 215.219 1.00 9.43  ? 89  ASP B CG  1 
ATOM   3893 O OD1 . ASP B 2 89  ? 170.046 165.901 215.964 1.00 9.43  ? 89  ASP B OD1 1 
ATOM   3894 O OD2 . ASP B 2 89  ? 168.276 166.740 214.983 1.00 9.43  ? 89  ASP B OD2 1 
ATOM   3895 N N   . ILE B 2 90  ? 171.101 163.639 212.315 1.00 8.92  ? 90  ILE B N   1 
ATOM   3896 C CA  . ILE B 2 90  ? 172.075 164.020 211.298 1.00 8.92  ? 90  ILE B CA  1 
ATOM   3897 C C   . ILE B 2 90  ? 171.497 165.020 210.305 1.00 8.92  ? 90  ILE B C   1 
ATOM   3898 O O   . ILE B 2 90  ? 172.097 166.063 210.051 1.00 8.92  ? 90  ILE B O   1 
ATOM   3899 C CB  . ILE B 2 90  ? 172.626 162.768 210.580 1.00 8.92  ? 90  ILE B CB  1 
ATOM   3900 C CG1 . ILE B 2 90  ? 173.400 161.873 211.550 1.00 8.92  ? 90  ILE B CG1 1 
ATOM   3901 C CG2 . ILE B 2 90  ? 173.525 163.168 209.448 1.00 8.92  ? 90  ILE B CG2 1 
ATOM   3902 C CD1 . ILE B 2 90  ? 172.567 160.832 212.260 1.00 8.92  ? 90  ILE B CD1 1 
ATOM   3903 N N   . HIS B 2 91  ? 170.330 164.719 209.733 1.00 8.81  ? 91  HIS B N   1 
ATOM   3904 C CA  . HIS B 2 91  ? 169.668 165.572 208.737 1.00 8.81  ? 91  HIS B CA  1 
ATOM   3905 C C   . HIS B 2 91  ? 170.484 165.680 207.445 1.00 8.81  ? 91  HIS B C   1 
ATOM   3906 O O   . HIS B 2 91  ? 170.709 166.769 206.921 1.00 8.81  ? 91  HIS B O   1 
ATOM   3907 C CB  . HIS B 2 91  ? 169.359 166.966 209.290 1.00 8.81  ? 91  HIS B CB  1 
ATOM   3908 C CG  . HIS B 2 91  ? 168.092 167.043 210.078 1.00 8.81  ? 91  HIS B CG  1 
ATOM   3909 N ND1 . HIS B 2 91  ? 168.074 167.141 211.451 1.00 8.81  ? 91  HIS B ND1 1 
ATOM   3910 C CD2 . HIS B 2 91  ? 166.798 167.025 209.686 1.00 8.81  ? 91  HIS B CD2 1 
ATOM   3911 C CE1 . HIS B 2 91  ? 166.824 167.191 211.871 1.00 8.81  ? 91  HIS B CE1 1 
ATOM   3912 N NE2 . HIS B 2 91  ? 166.029 167.118 210.819 1.00 8.81  ? 91  HIS B NE2 1 
ATOM   3913 N N   . GLY B 2 92  ? 170.917 164.537 206.928 1.00 11.89 ? 92  GLY B N   1 
ATOM   3914 C CA  . GLY B 2 92  ? 171.470 164.472 205.592 1.00 11.89 ? 92  GLY B CA  1 
ATOM   3915 C C   . GLY B 2 92  ? 172.913 164.898 205.431 1.00 11.89 ? 92  GLY B C   1 
ATOM   3916 O O   . GLY B 2 92  ? 173.419 164.875 204.304 1.00 11.89 ? 92  GLY B O   1 
ATOM   3917 N N   . GLN B 2 93  ? 173.604 165.270 206.506 1.00 10.40 ? 93  GLN B N   1 
ATOM   3918 C CA  . GLN B 2 93  ? 174.983 165.741 206.397 1.00 10.40 ? 93  GLN B CA  1 
ATOM   3919 C C   . GLN B 2 93  ? 175.914 164.532 206.308 1.00 10.40 ? 93  GLN B C   1 
ATOM   3920 O O   . GLN B 2 93  ? 176.498 164.069 207.289 1.00 10.40 ? 93  GLN B O   1 
ATOM   3921 C CB  . GLN B 2 93  ? 175.320 166.660 207.560 1.00 10.40 ? 93  GLN B CB  1 
ATOM   3922 C CG  . GLN B 2 93  ? 174.903 168.093 207.291 1.00 10.40 ? 93  GLN B CG  1 
ATOM   3923 C CD  . GLN B 2 93  ? 174.398 168.804 208.516 1.00 10.40 ? 93  GLN B CD  1 
ATOM   3924 O OE1 . GLN B 2 93  ? 174.591 168.344 209.634 1.00 10.40 ? 93  GLN B OE1 1 
ATOM   3925 N NE2 . GLN B 2 93  ? 173.735 169.934 208.312 1.00 10.40 ? 93  GLN B NE2 1 
ATOM   3926 N N   . PHE B 2 94  ? 176.046 164.020 205.082 1.00 21.39 ? 94  PHE B N   1 
ATOM   3927 C CA  . PHE B 2 94  ? 176.846 162.828 204.816 1.00 21.39 ? 94  PHE B CA  1 
ATOM   3928 C C   . PHE B 2 94  ? 178.314 163.056 205.165 1.00 21.39 ? 94  PHE B C   1 
ATOM   3929 O O   . PHE B 2 94  ? 178.931 162.266 205.902 1.00 21.39 ? 94  PHE B O   1 
ATOM   3930 C CB  . PHE B 2 94  ? 176.662 162.459 203.342 1.00 21.39 ? 94  PHE B CB  1 
ATOM   3931 C CG  . PHE B 2 94  ? 177.102 161.075 202.978 1.00 21.39 ? 94  PHE B CG  1 
ATOM   3932 C CD1 . PHE B 2 94  ? 178.423 160.730 202.955 1.00 21.39 ? 94  PHE B CD1 1 
ATOM   3933 C CD2 . PHE B 2 94  ? 176.175 160.116 202.648 1.00 21.39 ? 94  PHE B CD2 1 
ATOM   3934 C CE1 . PHE B 2 94  ? 178.813 159.454 202.610 1.00 21.39 ? 94  PHE B CE1 1 
ATOM   3935 C CE2 . PHE B 2 94  ? 176.564 158.842 202.314 1.00 21.39 ? 94  PHE B CE2 1 
ATOM   3936 C CZ  . PHE B 2 94  ? 177.883 158.513 202.297 1.00 21.39 ? 94  PHE B CZ  1 
ATOM   3937 N N   . PHE B 2 95  ? 178.884 164.152 204.665 1.00 10.27 ? 95  PHE B N   1 
ATOM   3938 C CA  . PHE B 2 95  ? 180.299 164.434 204.840 1.00 10.27 ? 95  PHE B CA  1 
ATOM   3939 C C   . PHE B 2 95  ? 180.656 164.722 206.287 1.00 10.27 ? 95  PHE B C   1 
ATOM   3940 O O   . PHE B 2 95  ? 181.844 164.792 206.608 1.00 10.27 ? 95  PHE B O   1 
ATOM   3941 C CB  . PHE B 2 95  ? 180.710 165.597 203.942 1.00 10.27 ? 95  PHE B CB  1 
ATOM   3942 C CG  . PHE B 2 95  ? 180.809 165.236 202.487 1.00 10.27 ? 95  PHE B CG  1 
ATOM   3943 C CD1 . PHE B 2 95  ? 179.672 165.046 201.729 1.00 10.27 ? 95  PHE B CD1 1 
ATOM   3944 C CD2 . PHE B 2 95  ? 182.038 165.075 201.882 1.00 10.27 ? 95  PHE B CD2 1 
ATOM   3945 C CE1 . PHE B 2 95  ? 179.757 164.709 200.403 1.00 10.27 ? 95  PHE B CE1 1 
ATOM   3946 C CE2 . PHE B 2 95  ? 182.127 164.741 200.555 1.00 10.27 ? 95  PHE B CE2 1 
ATOM   3947 C CZ  . PHE B 2 95  ? 180.986 164.557 199.815 1.00 10.27 ? 95  PHE B CZ  1 
ATOM   3948 N N   . ASP B 2 96  ? 179.662 164.908 207.154 1.00 13.68 ? 96  ASP B N   1 
ATOM   3949 C CA  . ASP B 2 96  ? 179.866 164.909 208.596 1.00 13.68 ? 96  ASP B CA  1 
ATOM   3950 C C   . ASP B 2 96  ? 179.544 163.565 209.225 1.00 13.68 ? 96  ASP B C   1 
ATOM   3951 O O   . ASP B 2 96  ? 180.034 163.268 210.318 1.00 13.68 ? 96  ASP B O   1 
ATOM   3952 C CB  . ASP B 2 96  ? 179.013 165.993 209.258 1.00 13.68 ? 96  ASP B CB  1 
ATOM   3953 C CG  . ASP B 2 96  ? 179.399 167.380 208.811 1.00 13.68 ? 96  ASP B CG  1 
ATOM   3954 O OD1 . ASP B 2 96  ? 180.590 167.587 208.507 1.00 13.68 ? 96  ASP B OD1 1 
ATOM   3955 O OD2 . ASP B 2 96  ? 178.517 168.262 208.760 1.00 13.68 ? 96  ASP B OD2 1 
ATOM   3956 N N   . LEU B 2 97  ? 178.722 162.752 208.562 1.00 9.67  ? 97  LEU B N   1 
ATOM   3957 C CA  . LEU B 2 97  ? 178.482 161.400 209.047 1.00 9.67  ? 97  LEU B CA  1 
ATOM   3958 C C   . LEU B 2 97  ? 179.771 160.587 209.058 1.00 9.67  ? 97  LEU B C   1 
ATOM   3959 O O   . LEU B 2 97  ? 180.046 159.860 210.024 1.00 9.67  ? 97  LEU B O   1 
ATOM   3960 C CB  . LEU B 2 97  ? 177.409 160.724 208.197 1.00 9.67  ? 97  LEU B CB  1 
ATOM   3961 C CG  . LEU B 2 97  ? 177.339 159.205 208.227 1.00 9.67  ? 97  LEU B CG  1 
ATOM   3962 C CD1 . LEU B 2 97  ? 176.808 158.768 209.556 1.00 9.67  ? 97  LEU B CD1 1 
ATOM   3963 C CD2 . LEU B 2 97  ? 176.432 158.719 207.129 1.00 9.67  ? 97  LEU B CD2 1 
ATOM   3964 N N   . MET B 2 98  ? 180.600 160.710 208.015 1.00 14.29 ? 98  MET B N   1 
ATOM   3965 C CA  . MET B 2 98  ? 181.894 160.021 208.089 1.00 14.29 ? 98  MET B CA  1 
ATOM   3966 C C   . MET B 2 98  ? 182.741 160.534 209.242 1.00 14.29 ? 98  MET B C   1 
ATOM   3967 O O   . MET B 2 98  ? 183.395 159.746 209.932 1.00 14.29 ? 98  MET B O   1 
ATOM   3968 C CB  . MET B 2 98  ? 182.697 160.114 206.798 1.00 14.29 ? 98  MET B CB  1 
ATOM   3969 C CG  . MET B 2 98  ? 182.229 159.198 205.735 1.00 14.29 ? 98  MET B CG  1 
ATOM   3970 S SD  . MET B 2 98  ? 180.730 159.851 205.114 1.00 14.29 ? 98  MET B SD  1 
ATOM   3971 C CE  . MET B 2 98  ? 181.444 161.201 204.198 1.00 14.29 ? 98  MET B CE  1 
ATOM   3972 N N   . LYS B 2 99  ? 182.774 161.851 209.450 1.00 12.92 ? 99  LYS B N   1 
ATOM   3973 C CA  . LYS B 2 99  ? 183.560 162.376 210.558 1.00 12.92 ? 99  LYS B CA  1 
ATOM   3974 C C   . LYS B 2 99  ? 183.075 161.810 211.880 1.00 12.92 ? 99  LYS B C   1 
ATOM   3975 O O   . LYS B 2 99  ? 183.888 161.483 212.753 1.00 12.92 ? 99  LYS B O   1 
ATOM   3976 C CB  . LYS B 2 99  ? 183.503 163.899 210.581 1.00 12.92 ? 99  LYS B CB  1 
ATOM   3977 C CG  . LYS B 2 99  ? 184.322 164.510 211.692 1.00 12.92 ? 99  LYS B CG  1 
ATOM   3978 C CD  . LYS B 2 99  ? 185.768 164.081 211.578 1.00 12.92 ? 99  LYS B CD  1 
ATOM   3979 C CE  . LYS B 2 99  ? 186.641 164.732 212.636 1.00 12.92 ? 99  LYS B CE  1 
ATOM   3980 N NZ  . LYS B 2 99  ? 186.918 166.166 212.333 1.00 12.92 ? 99  LYS B NZ  1 
ATOM   3981 N N   . LEU B 2 100 ? 181.758 161.670 212.034 1.00 11.47 ? 100 LEU B N   1 
ATOM   3982 C CA  . LEU B 2 100 ? 181.211 160.979 213.195 1.00 11.47 ? 100 LEU B CA  1 
ATOM   3983 C C   . LEU B 2 100 ? 181.797 159.582 213.315 1.00 11.47 ? 100 LEU B C   1 
ATOM   3984 O O   . LEU B 2 100 ? 182.202 159.155 214.401 1.00 11.47 ? 100 LEU B O   1 
ATOM   3985 C CB  . LEU B 2 100 ? 179.688 160.919 213.098 1.00 11.47 ? 100 LEU B CB  1 
ATOM   3986 C CG  . LEU B 2 100 ? 178.976 159.841 213.913 1.00 11.47 ? 100 LEU B CG  1 
ATOM   3987 C CD1 . LEU B 2 100 ? 179.272 159.983 215.380 1.00 11.47 ? 100 LEU B CD1 1 
ATOM   3988 C CD2 . LEU B 2 100 ? 177.481 159.896 213.674 1.00 11.47 ? 100 LEU B CD2 1 
ATOM   3989 N N   . PHE B 2 101 ? 181.860 158.857 212.202 1.00 10.99 ? 101 PHE B N   1 
ATOM   3990 C CA  . PHE B 2 101 ? 182.347 157.485 212.282 1.00 10.99 ? 101 PHE B CA  1 
ATOM   3991 C C   . PHE B 2 101 ? 183.834 157.420 212.619 1.00 10.99 ? 101 PHE B C   1 
ATOM   3992 O O   . PHE B 2 101 ? 184.264 156.482 213.297 1.00 10.99 ? 101 PHE B O   1 
ATOM   3993 C CB  . PHE B 2 101 ? 182.046 156.738 210.986 1.00 10.99 ? 101 PHE B CB  1 
ATOM   3994 C CG  . PHE B 2 101 ? 180.680 156.127 210.957 1.00 10.99 ? 101 PHE B CG  1 
ATOM   3995 C CD1 . PHE B 2 101 ? 180.262 155.301 211.971 1.00 10.99 ? 101 PHE B CD1 1 
ATOM   3996 C CD2 . PHE B 2 101 ? 179.810 156.392 209.927 1.00 10.99 ? 101 PHE B CD2 1 
ATOM   3997 C CE1 . PHE B 2 101 ? 179.011 154.747 211.948 1.00 10.99 ? 101 PHE B CE1 1 
ATOM   3998 C CE2 . PHE B 2 101 ? 178.558 155.833 209.906 1.00 10.99 ? 101 PHE B CE2 1 
ATOM   3999 C CZ  . PHE B 2 101 ? 178.160 155.015 210.914 1.00 10.99 ? 101 PHE B CZ  1 
ATOM   4000 N N   . GLU B 2 102 ? 184.638 158.385 212.164 1.00 15.80 ? 102 GLU B N   1 
ATOM   4001 C CA  . GLU B 2 102 ? 186.051 158.350 212.547 1.00 15.80 ? 102 GLU B CA  1 
ATOM   4002 C C   . GLU B 2 102 ? 186.280 158.879 213.958 1.00 15.80 ? 102 GLU B C   1 
ATOM   4003 O O   . GLU B 2 102 ? 187.336 158.616 214.543 1.00 15.80 ? 102 GLU B O   1 
ATOM   4004 C CB  . GLU B 2 102 ? 186.968 159.114 211.580 1.00 15.80 ? 102 GLU B CB  1 
ATOM   4005 C CG  . GLU B 2 102 ? 187.268 158.430 210.240 1.00 15.80 ? 102 GLU B CG  1 
ATOM   4006 C CD  . GLU B 2 102 ? 186.449 158.942 209.075 1.00 15.80 ? 102 GLU B CD  1 
ATOM   4007 O OE1 . GLU B 2 102 ? 185.762 159.963 209.235 1.00 15.80 ? 102 GLU B OE1 1 
ATOM   4008 O OE2 . GLU B 2 102 ? 186.499 158.323 207.994 1.00 15.80 ? 102 GLU B OE2 1 
ATOM   4009 N N   . VAL B 2 103 ? 185.332 159.630 214.519 1.00 21.39 ? 103 VAL B N   1 
ATOM   4010 C CA  . VAL B 2 103 ? 185.517 160.139 215.877 1.00 21.39 ? 103 VAL B CA  1 
ATOM   4011 C C   . VAL B 2 103 ? 185.126 159.093 216.912 1.00 21.39 ? 103 VAL B C   1 
ATOM   4012 O O   . VAL B 2 103 ? 185.882 158.811 217.848 1.00 21.39 ? 103 VAL B O   1 
ATOM   4013 C CB  . VAL B 2 103 ? 184.733 161.447 216.081 1.00 21.39 ? 103 VAL B CB  1 
ATOM   4014 C CG1 . VAL B 2 103 ? 184.725 161.823 217.542 1.00 21.39 ? 103 VAL B CG1 1 
ATOM   4015 C CG2 . VAL B 2 103 ? 185.368 162.562 215.283 1.00 21.39 ? 103 VAL B CG2 1 
ATOM   4016 N N   . GLY B 2 104 ? 183.950 158.497 216.762 1.00 12.84 ? 104 GLY B N   1 
ATOM   4017 C CA  . GLY B 2 104 ? 183.453 157.573 217.760 1.00 12.84 ? 104 GLY B CA  1 
ATOM   4018 C C   . GLY B 2 104 ? 183.851 156.127 217.550 1.00 12.84 ? 104 GLY B C   1 
ATOM   4019 O O   . GLY B 2 104 ? 183.243 155.225 218.131 1.00 12.84 ? 104 GLY B O   1 
ATOM   4020 N N   . GLY B 2 105 ? 184.858 155.884 216.720 1.00 12.74 ? 105 GLY B N   1 
ATOM   4021 C CA  . GLY B 2 105 ? 185.291 154.526 216.463 1.00 12.74 ? 105 GLY B CA  1 
ATOM   4022 C C   . GLY B 2 105 ? 184.450 153.850 215.403 1.00 12.74 ? 105 GLY B C   1 
ATOM   4023 O O   . GLY B 2 105 ? 183.220 153.928 215.441 1.00 12.74 ? 105 GLY B O   1 
ATOM   4024 N N   . SER B 2 106 ? 185.100 153.182 214.456 1.00 15.11 ? 106 SER B N   1 
ATOM   4025 C CA  . SER B 2 106 ? 184.398 152.570 213.343 1.00 15.11 ? 106 SER B CA  1 
ATOM   4026 C C   . SER B 2 106 ? 183.522 151.417 213.829 1.00 15.11 ? 106 SER B C   1 
ATOM   4027 O O   . SER B 2 106 ? 183.800 150.812 214.866 1.00 15.11 ? 106 SER B O   1 
ATOM   4028 C CB  . SER B 2 106 ? 185.402 152.081 212.304 1.00 15.11 ? 106 SER B CB  1 
ATOM   4029 O OG  . SER B 2 106 ? 186.119 153.167 211.745 1.00 15.11 ? 106 SER B OG  1 
ATOM   4030 N N   . PRO B 2 107 ? 182.452 151.092 213.094 1.00 12.72 ? 107 PRO B N   1 
ATOM   4031 C CA  . PRO B 2 107 ? 181.504 150.076 213.582 1.00 12.72 ? 107 PRO B CA  1 
ATOM   4032 C C   . PRO B 2 107 ? 182.107 148.697 213.768 1.00 12.72 ? 107 PRO B C   1 
ATOM   4033 O O   . PRO B 2 107 ? 181.415 147.811 214.284 1.00 12.72 ? 107 PRO B O   1 
ATOM   4034 C CB  . PRO B 2 107 ? 180.416 150.054 212.500 1.00 12.72 ? 107 PRO B CB  1 
ATOM   4035 C CG  . PRO B 2 107 ? 180.558 151.322 211.784 1.00 12.72 ? 107 PRO B CG  1 
ATOM   4036 C CD  . PRO B 2 107 ? 182.004 151.681 211.824 1.00 12.72 ? 107 PRO B CD  1 
ATOM   4037 N N   . ALA B 2 108 ? 183.357 148.477 213.358 1.00 13.56 ? 108 ALA B N   1 
ATOM   4038 C CA  . ALA B 2 108 ? 183.956 147.158 213.510 1.00 13.56 ? 108 ALA B CA  1 
ATOM   4039 C C   . ALA B 2 108 ? 184.096 146.774 214.978 1.00 13.56 ? 108 ALA B C   1 
ATOM   4040 O O   . ALA B 2 108 ? 183.838 145.625 215.353 1.00 13.56 ? 108 ALA B O   1 
ATOM   4041 C CB  . ALA B 2 108 ? 185.312 147.118 212.812 1.00 13.56 ? 108 ALA B CB  1 
ATOM   4042 N N   . ASN B 2 109 ? 184.494 147.721 215.825 1.00 18.33 ? 109 ASN B N   1 
ATOM   4043 C CA  . ASN B 2 109 ? 184.807 147.430 217.218 1.00 18.33 ? 109 ASN B CA  1 
ATOM   4044 C C   . ASN B 2 109 ? 183.801 147.981 218.216 1.00 18.33 ? 109 ASN B C   1 
ATOM   4045 O O   . ASN B 2 109 ? 183.658 147.412 219.299 1.00 18.33 ? 109 ASN B O   1 
ATOM   4046 C CB  . ASN B 2 109 ? 186.194 147.977 217.571 1.00 18.33 ? 109 ASN B CB  1 
ATOM   4047 C CG  . ASN B 2 109 ? 187.265 147.500 216.616 1.00 18.33 ? 109 ASN B CG  1 
ATOM   4048 O OD1 . ASN B 2 109 ? 187.272 146.340 216.206 1.00 18.33 ? 109 ASN B OD1 1 
ATOM   4049 N ND2 . ASN B 2 109 ? 188.178 148.394 216.255 1.00 18.33 ? 109 ASN B ND2 1 
ATOM   4050 N N   . THR B 2 110 ? 183.106 149.068 217.891 1.00 15.12 ? 110 THR B N   1 
ATOM   4051 C CA  . THR B 2 110 ? 182.172 149.694 218.813 1.00 15.12 ? 110 THR B CA  1 
ATOM   4052 C C   . THR B 2 110 ? 180.815 149.848 218.148 1.00 15.12 ? 110 THR B C   1 
ATOM   4053 O O   . THR B 2 110 ? 180.711 149.911 216.922 1.00 15.12 ? 110 THR B O   1 
ATOM   4054 C CB  . THR B 2 110 ? 182.670 151.055 219.276 1.00 15.12 ? 110 THR B CB  1 
ATOM   4055 O OG1 . THR B 2 110 ? 181.767 151.581 220.255 1.00 15.12 ? 110 THR B OG1 1 
ATOM   4056 C CG2 . THR B 2 110 ? 182.755 152.008 218.102 1.00 15.12 ? 110 THR B CG2 1 
ATOM   4057 N N   . ARG B 2 111 ? 179.773 149.908 218.970 1.00 23.61 ? 111 ARG B N   1 
ATOM   4058 C CA  . ARG B 2 111 ? 178.402 149.893 218.488 1.00 23.61 ? 111 ARG B CA  1 
ATOM   4059 C C   . ARG B 2 111 ? 177.750 151.255 218.673 1.00 23.61 ? 111 ARG B C   1 
ATOM   4060 O O   . ARG B 2 111 ? 178.188 152.066 219.490 1.00 23.61 ? 111 ARG B O   1 
ATOM   4061 C CB  . ARG B 2 111 ? 177.586 148.818 219.201 1.00 23.61 ? 111 ARG B CB  1 
ATOM   4062 C CG  . ARG B 2 111 ? 176.867 149.275 220.437 1.00 23.61 ? 111 ARG B CG  1 
ATOM   4063 C CD  . ARG B 2 111 ? 176.228 148.088 221.118 1.00 23.61 ? 111 ARG B CD  1 
ATOM   4064 N NE  . ARG B 2 111 ? 177.236 147.213 221.697 1.00 23.61 ? 111 ARG B NE  1 
ATOM   4065 C CZ  . ARG B 2 111 ? 176.958 146.098 222.358 1.00 23.61 ? 111 ARG B CZ  1 
ATOM   4066 N NH1 . ARG B 2 111 ? 175.699 145.723 222.524 1.00 23.61 ? 111 ARG B NH1 1 
ATOM   4067 N NH2 . ARG B 2 111 ? 177.940 145.361 222.852 1.00 23.61 ? 111 ARG B NH2 1 
ATOM   4068 N N   . TYR B 2 112 ? 176.693 151.493 217.908 1.00 13.44 ? 112 TYR B N   1 
ATOM   4069 C CA  . TYR B 2 112 ? 176.053 152.793 217.819 1.00 13.44 ? 112 TYR B CA  1 
ATOM   4070 C C   . TYR B 2 112 ? 174.562 152.669 218.086 1.00 13.44 ? 112 TYR B C   1 
ATOM   4071 O O   . TYR B 2 112 ? 173.956 151.611 217.911 1.00 13.44 ? 112 TYR B O   1 
ATOM   4072 C CB  . TYR B 2 112 ? 176.283 153.419 216.440 1.00 13.44 ? 112 TYR B CB  1 
ATOM   4073 C CG  . TYR B 2 112 ? 177.680 153.929 216.226 1.00 13.44 ? 112 TYR B CG  1 
ATOM   4074 C CD1 . TYR B 2 112 ? 178.080 155.137 216.760 1.00 13.44 ? 112 TYR B CD1 1 
ATOM   4075 C CD2 . TYR B 2 112 ? 178.600 153.200 215.504 1.00 13.44 ? 112 TYR B CD2 1 
ATOM   4076 C CE1 . TYR B 2 112 ? 179.351 155.606 216.576 1.00 13.44 ? 112 TYR B CE1 1 
ATOM   4077 C CE2 . TYR B 2 112 ? 179.873 153.662 215.314 1.00 13.44 ? 112 TYR B CE2 1 
ATOM   4078 C CZ  . TYR B 2 112 ? 180.244 154.866 215.854 1.00 13.44 ? 112 TYR B CZ  1 
ATOM   4079 O OH  . TYR B 2 112 ? 181.519 155.338 215.672 1.00 13.44 ? 112 TYR B OH  1 
ATOM   4080 N N   . LEU B 2 113 ? 173.969 153.790 218.483 1.00 21.39 ? 113 LEU B N   1 
ATOM   4081 C CA  . LEU B 2 113 ? 172.534 153.866 218.735 1.00 21.39 ? 113 LEU B CA  1 
ATOM   4082 C C   . LEU B 2 113 ? 172.078 155.215 218.191 1.00 21.39 ? 113 LEU B C   1 
ATOM   4083 O O   . LEU B 2 113 ? 172.252 156.237 218.854 1.00 21.39 ? 113 LEU B O   1 
ATOM   4084 C CB  . LEU B 2 113 ? 172.239 153.729 220.221 1.00 21.39 ? 113 LEU B CB  1 
ATOM   4085 C CG  . LEU B 2 113 ? 170.865 154.132 220.744 1.00 21.39 ? 113 LEU B CG  1 
ATOM   4086 C CD1 . LEU B 2 113 ? 169.856 153.230 220.145 1.00 21.39 ? 113 LEU B CD1 1 
ATOM   4087 C CD2 . LEU B 2 113 ? 170.813 154.038 222.248 1.00 21.39 ? 113 LEU B CD2 1 
ATOM   4088 N N   . PHE B 2 114 ? 171.522 155.219 216.986 1.00 11.04 ? 114 PHE B N   1 
ATOM   4089 C CA  . PHE B 2 114 ? 171.159 156.465 216.324 1.00 11.04 ? 114 PHE B CA  1 
ATOM   4090 C C   . PHE B 2 114 ? 169.752 156.864 216.736 1.00 11.04 ? 114 PHE B C   1 
ATOM   4091 O O   . PHE B 2 114 ? 168.787 156.175 216.399 1.00 11.04 ? 114 PHE B O   1 
ATOM   4092 C CB  . PHE B 2 114 ? 171.255 156.325 214.810 1.00 11.04 ? 114 PHE B CB  1 
ATOM   4093 C CG  . PHE B 2 114 ? 172.656 156.351 214.294 1.00 11.04 ? 114 PHE B CG  1 
ATOM   4094 C CD1 . PHE B 2 114 ? 173.391 155.192 214.200 1.00 11.04 ? 114 PHE B CD1 1 
ATOM   4095 C CD2 . PHE B 2 114 ? 173.237 157.537 213.903 1.00 11.04 ? 114 PHE B CD2 1 
ATOM   4096 C CE1 . PHE B 2 114 ? 174.670 155.215 213.731 1.00 11.04 ? 114 PHE B CE1 1 
ATOM   4097 C CE2 . PHE B 2 114 ? 174.518 157.562 213.433 1.00 11.04 ? 114 PHE B CE2 1 
ATOM   4098 C CZ  . PHE B 2 114 ? 175.234 156.400 213.348 1.00 11.04 ? 114 PHE B CZ  1 
ATOM   4099 N N   . LEU B 2 115 ? 169.634 157.988 217.441 1.00 11.12 ? 115 LEU B N   1 
ATOM   4100 C CA  . LEU B 2 115 ? 168.358 158.359 218.040 1.00 11.12 ? 115 LEU B CA  1 
ATOM   4101 C C   . LEU B 2 115 ? 167.412 158.997 217.036 1.00 11.12 ? 115 LEU B C   1 
ATOM   4102 O O   . LEU B 2 115 ? 166.251 158.596 216.937 1.00 11.12 ? 115 LEU B O   1 
ATOM   4103 C CB  . LEU B 2 115 ? 168.584 159.316 219.205 1.00 11.12 ? 115 LEU B CB  1 
ATOM   4104 C CG  . LEU B 2 115 ? 169.187 158.724 220.468 1.00 11.12 ? 115 LEU B CG  1 
ATOM   4105 C CD1 . LEU B 2 115 ? 169.334 159.792 221.516 1.00 11.12 ? 115 LEU B CD1 1 
ATOM   4106 C CD2 . LEU B 2 115 ? 168.313 157.610 220.966 1.00 11.12 ? 115 LEU B CD2 1 
ATOM   4107 N N   . GLY B 2 116 ? 167.879 159.986 216.281 1.00 21.39 ? 116 GLY B N   1 
ATOM   4108 C CA  . GLY B 2 116 ? 167.008 160.898 215.586 1.00 21.39 ? 116 GLY B CA  1 
ATOM   4109 C C   . GLY B 2 116 ? 166.893 160.641 214.096 1.00 21.39 ? 116 GLY B C   1 
ATOM   4110 O O   . GLY B 2 116 ? 167.341 159.623 213.566 1.00 21.39 ? 116 GLY B O   1 
ATOM   4111 N N   . ASP B 2 117 ? 166.275 161.607 213.424 1.00 9.90  ? 117 ASP B N   1 
ATOM   4112 C CA  . ASP B 2 117 ? 165.976 161.547 212.004 1.00 9.90  ? 117 ASP B CA  1 
ATOM   4113 C C   . ASP B 2 117 ? 167.231 161.725 211.160 1.00 9.90  ? 117 ASP B C   1 
ATOM   4114 O O   . ASP B 2 117 ? 168.292 162.108 211.651 1.00 9.90  ? 117 ASP B O   1 
ATOM   4115 C CB  . ASP B 2 117 ? 164.943 162.609 211.660 1.00 9.90  ? 117 ASP B CB  1 
ATOM   4116 C CG  . ASP B 2 117 ? 165.444 164.002 211.930 1.00 9.90  ? 117 ASP B CG  1 
ATOM   4117 O OD1 . ASP B 2 117 ? 166.572 164.144 212.423 1.00 9.90  ? 117 ASP B OD1 1 
ATOM   4118 O OD2 . ASP B 2 117 ? 164.710 164.966 211.665 1.00 9.90  ? 117 ASP B OD2 1 
ATOM   4119 N N   . TYR B 2 118 ? 167.092 161.449 209.863 1.00 10.51 ? 118 TYR B N   1 
ATOM   4120 C CA  . TYR B 2 118 ? 168.232 161.427 208.958 1.00 10.51 ? 118 TYR B CA  1 
ATOM   4121 C C   . TYR B 2 118 ? 168.051 162.246 207.694 1.00 10.51 ? 118 TYR B C   1 
ATOM   4122 O O   . TYR B 2 118 ? 169.059 162.653 207.108 1.00 10.51 ? 118 TYR B O   1 
ATOM   4123 C CB  . TYR B 2 118 ? 168.556 159.988 208.522 1.00 10.51 ? 118 TYR B CB  1 
ATOM   4124 C CG  . TYR B 2 118 ? 168.573 158.974 209.636 1.00 10.51 ? 118 TYR B CG  1 
ATOM   4125 C CD1 . TYR B 2 118 ? 169.644 158.873 210.502 1.00 10.51 ? 118 TYR B CD1 1 
ATOM   4126 C CD2 . TYR B 2 118 ? 167.512 158.105 209.809 1.00 10.51 ? 118 TYR B CD2 1 
ATOM   4127 C CE1 . TYR B 2 118 ? 169.643 157.943 211.517 1.00 10.51 ? 118 TYR B CE1 1 
ATOM   4128 C CE2 . TYR B 2 118 ? 167.502 157.180 210.817 1.00 10.51 ? 118 TYR B CE2 1 
ATOM   4129 C CZ  . TYR B 2 118 ? 168.567 157.100 211.665 1.00 10.51 ? 118 TYR B CZ  1 
ATOM   4130 O OH  . TYR B 2 118 ? 168.551 156.167 212.667 1.00 10.51 ? 118 TYR B OH  1 
ATOM   4131 N N   . VAL B 2 119 ? 166.825 162.513 207.252 1.00 11.76 ? 119 VAL B N   1 
ATOM   4132 C CA  . VAL B 2 119 ? 166.610 162.782 205.835 1.00 11.76 ? 119 VAL B CA  1 
ATOM   4133 C C   . VAL B 2 119 ? 166.447 164.258 205.475 1.00 11.76 ? 119 VAL B C   1 
ATOM   4134 O O   . VAL B 2 119 ? 167.262 164.804 204.726 1.00 11.76 ? 119 VAL B O   1 
ATOM   4135 C CB  . VAL B 2 119 ? 165.414 161.955 205.335 1.00 11.76 ? 119 VAL B CB  1 
ATOM   4136 C CG1 . VAL B 2 119 ? 165.812 160.504 205.240 1.00 11.76 ? 119 VAL B CG1 1 
ATOM   4137 C CG2 . VAL B 2 119 ? 164.262 162.073 206.290 1.00 11.76 ? 119 VAL B CG2 1 
ATOM   4138 N N   . ASP B 2 120 ? 165.415 164.921 205.982 1.00 13.36 ? 120 ASP B N   1 
ATOM   4139 C CA  . ASP B 2 120 ? 165.072 166.228 205.439 1.00 13.36 ? 120 ASP B CA  1 
ATOM   4140 C C   . ASP B 2 120 ? 166.121 167.277 205.799 1.00 13.36 ? 120 ASP B C   1 
ATOM   4141 O O   . ASP B 2 120 ? 166.952 167.085 206.687 1.00 13.36 ? 120 ASP B O   1 
ATOM   4142 C CB  . ASP B 2 120 ? 163.701 166.675 205.936 1.00 13.36 ? 120 ASP B CB  1 
ATOM   4143 C CG  . ASP B 2 120 ? 162.576 165.846 205.360 1.00 13.36 ? 120 ASP B CG  1 
ATOM   4144 O OD1 . ASP B 2 120 ? 162.733 165.337 204.233 1.00 13.36 ? 120 ASP B OD1 1 
ATOM   4145 O OD2 . ASP B 2 120 ? 161.529 165.712 206.025 1.00 13.36 ? 120 ASP B OD2 1 
ATOM   4146 N N   . ARG B 2 121 ? 166.079 168.393 205.064 1.00 10.20 ? 121 ARG B N   1 
ATOM   4147 C CA  . ARG B 2 121 ? 166.916 169.572 205.311 1.00 10.20 ? 121 ARG B CA  1 
ATOM   4148 C C   . ARG B 2 121 ? 168.393 169.305 205.016 1.00 10.20 ? 121 ARG B C   1 
ATOM   4149 O O   . ARG B 2 121 ? 169.275 169.726 205.764 1.00 10.20 ? 121 ARG B O   1 
ATOM   4150 C CB  . ARG B 2 121 ? 166.740 170.093 206.737 1.00 10.20 ? 121 ARG B CB  1 
ATOM   4151 C CG  . ARG B 2 121 ? 165.632 171.103 206.886 1.00 10.20 ? 121 ARG B CG  1 
ATOM   4152 C CD  . ARG B 2 121 ? 165.726 171.810 208.216 1.00 10.20 ? 121 ARG B CD  1 
ATOM   4153 N NE  . ARG B 2 121 ? 165.107 171.040 209.285 1.00 10.20 ? 121 ARG B NE  1 
ATOM   4154 C CZ  . ARG B 2 121 ? 163.972 171.380 209.883 1.00 10.20 ? 121 ARG B CZ  1 
ATOM   4155 N NH1 . ARG B 2 121 ? 163.334 172.479 209.514 1.00 10.20 ? 121 ARG B NH1 1 
ATOM   4156 N NH2 . ARG B 2 121 ? 163.475 170.626 210.852 1.00 10.20 ? 121 ARG B NH2 1 
ATOM   4157 N N   . GLY B 2 122 ? 168.664 168.618 203.911 1.00 10.80 ? 122 GLY B N   1 
ATOM   4158 C CA  . GLY B 2 122 ? 170.024 168.352 203.486 1.00 10.80 ? 122 GLY B CA  1 
ATOM   4159 C C   . GLY B 2 122 ? 170.048 167.793 202.081 1.00 10.80 ? 122 GLY B C   1 
ATOM   4160 O O   . GLY B 2 122 ? 169.071 167.179 201.645 1.00 10.80 ? 122 GLY B O   1 
ATOM   4161 N N   . TYR B 2 123 ? 171.145 167.994 201.357 1.00 10.57 ? 123 TYR B N   1 
ATOM   4162 C CA  . TYR B 2 123 ? 171.193 167.599 199.957 1.00 10.57 ? 123 TYR B CA  1 
ATOM   4163 C C   . TYR B 2 123 ? 171.758 166.201 199.736 1.00 10.57 ? 123 TYR B C   1 
ATOM   4164 O O   . TYR B 2 123 ? 171.673 165.688 198.615 1.00 10.57 ? 123 TYR B O   1 
ATOM   4165 C CB  . TYR B 2 123 ? 172.005 168.621 199.156 1.00 10.57 ? 123 TYR B CB  1 
ATOM   4166 C CG  . TYR B 2 123 ? 171.349 169.979 199.099 1.00 10.57 ? 123 TYR B CG  1 
ATOM   4167 C CD1 . TYR B 2 123 ? 170.015 170.106 198.747 1.00 10.57 ? 123 TYR B CD1 1 
ATOM   4168 C CD2 . TYR B 2 123 ? 172.055 171.130 199.403 1.00 10.57 ? 123 TYR B CD2 1 
ATOM   4169 C CE1 . TYR B 2 123 ? 169.402 171.333 198.698 1.00 10.57 ? 123 TYR B CE1 1 
ATOM   4170 C CE2 . TYR B 2 123 ? 171.447 172.366 199.356 1.00 10.57 ? 123 TYR B CE2 1 
ATOM   4171 C CZ  . TYR B 2 123 ? 170.120 172.458 199.002 1.00 10.57 ? 123 TYR B CZ  1 
ATOM   4172 O OH  . TYR B 2 123 ? 169.502 173.682 198.950 1.00 10.57 ? 123 TYR B OH  1 
ATOM   4173 N N   . PHE B 2 124 ? 172.307 165.565 200.768 1.00 12.00 ? 124 PHE B N   1 
ATOM   4174 C CA  . PHE B 2 124 ? 172.882 164.233 200.631 1.00 12.00 ? 124 PHE B CA  1 
ATOM   4175 C C   . PHE B 2 124 ? 172.179 163.238 201.542 1.00 12.00 ? 124 PHE B C   1 
ATOM   4176 O O   . PHE B 2 124 ? 172.837 162.489 202.268 1.00 12.00 ? 124 PHE B O   1 
ATOM   4177 C CB  . PHE B 2 124 ? 174.376 164.255 200.947 1.00 12.00 ? 124 PHE B CB  1 
ATOM   4178 C CG  . PHE B 2 124 ? 175.135 165.328 200.230 1.00 12.00 ? 124 PHE B CG  1 
ATOM   4179 C CD1 . PHE B 2 124 ? 175.250 165.309 198.855 1.00 12.00 ? 124 PHE B CD1 1 
ATOM   4180 C CD2 . PHE B 2 124 ? 175.743 166.348 200.930 1.00 12.00 ? 124 PHE B CD2 1 
ATOM   4181 C CE1 . PHE B 2 124 ? 175.950 166.293 198.193 1.00 12.00 ? 124 PHE B CE1 1 
ATOM   4182 C CE2 . PHE B 2 124 ? 176.442 167.329 200.273 1.00 12.00 ? 124 PHE B CE2 1 
ATOM   4183 C CZ  . PHE B 2 124 ? 176.545 167.302 198.902 1.00 12.00 ? 124 PHE B CZ  1 
ATOM   4184 N N   . SER B 2 125 ? 170.845 163.232 201.532 1.00 12.56 ? 125 SER B N   1 
ATOM   4185 C CA  . SER B 2 125 ? 170.104 162.378 202.453 1.00 12.56 ? 125 SER B CA  1 
ATOM   4186 C C   . SER B 2 125 ? 169.948 160.959 201.925 1.00 12.56 ? 125 SER B C   1 
ATOM   4187 O O   . SER B 2 125 ? 170.022 160.001 202.702 1.00 12.56 ? 125 SER B O   1 
ATOM   4188 C CB  . SER B 2 125 ? 168.736 162.981 202.737 1.00 12.56 ? 125 SER B CB  1 
ATOM   4189 O OG  . SER B 2 125 ? 167.989 163.102 201.545 1.00 12.56 ? 125 SER B OG  1 
ATOM   4190 N N   . ILE B 2 126 ? 169.712 160.796 200.621 1.00 12.96 ? 126 ILE B N   1 
ATOM   4191 C CA  . ILE B 2 126 ? 169.565 159.450 200.075 1.00 12.96 ? 126 ILE B CA  1 
ATOM   4192 C C   . ILE B 2 126 ? 170.870 158.681 200.211 1.00 12.96 ? 126 ILE B C   1 
ATOM   4193 O O   . ILE B 2 126 ? 170.875 157.493 200.553 1.00 12.96 ? 126 ILE B O   1 
ATOM   4194 C CB  . ILE B 2 126 ? 169.074 159.497 198.616 1.00 12.96 ? 126 ILE B CB  1 
ATOM   4195 C CG1 . ILE B 2 126 ? 168.800 158.087 198.104 1.00 12.96 ? 126 ILE B CG1 1 
ATOM   4196 C CG2 . ILE B 2 126 ? 170.083 160.171 197.718 1.00 12.96 ? 126 ILE B CG2 1 
ATOM   4197 C CD1 . ILE B 2 126 ? 167.823 157.321 198.939 1.00 12.96 ? 126 ILE B CD1 1 
ATOM   4198 N N   . GLU B 2 127 ? 171.998 159.350 199.978 1.00 13.74 ? 127 GLU B N   1 
ATOM   4199 C CA  . GLU B 2 127 ? 173.286 158.702 200.169 1.00 13.74 ? 127 GLU B CA  1 
ATOM   4200 C C   . GLU B 2 127 ? 173.482 158.310 201.626 1.00 13.74 ? 127 GLU B C   1 
ATOM   4201 O O   . GLU B 2 127 ? 173.980 157.217 201.921 1.00 13.74 ? 127 GLU B O   1 
ATOM   4202 C CB  . GLU B 2 127 ? 174.400 159.629 199.690 1.00 13.74 ? 127 GLU B CB  1 
ATOM   4203 C CG  . GLU B 2 127 ? 174.149 160.195 198.298 1.00 13.74 ? 127 GLU B CG  1 
ATOM   4204 C CD  . GLU B 2 127 ? 175.252 161.120 197.805 1.00 13.74 ? 127 GLU B CD  1 
ATOM   4205 O OE1 . GLU B 2 127 ? 176.260 161.306 198.517 1.00 13.74 ? 127 GLU B OE1 1 
ATOM   4206 O OE2 . GLU B 2 127 ? 175.106 161.666 196.693 1.00 13.74 ? 127 GLU B OE2 1 
ATOM   4207 N N   . CYS B 2 128 ? 173.081 159.184 202.551 1.00 10.32 ? 128 CYS B N   1 
ATOM   4208 C CA  . CYS B 2 128 ? 173.252 158.903 203.973 1.00 10.32 ? 128 CYS B CA  1 
ATOM   4209 C C   . CYS B 2 128 ? 172.441 157.688 204.395 1.00 10.32 ? 128 CYS B C   1 
ATOM   4210 O O   . CYS B 2 128 ? 172.950 156.800 205.089 1.00 10.32 ? 128 CYS B O   1 
ATOM   4211 C CB  . CYS B 2 128 ? 172.855 160.125 204.797 1.00 10.32 ? 128 CYS B CB  1 
ATOM   4212 S SG  . CYS B 2 128 ? 172.966 159.886 206.566 1.00 10.32 ? 128 CYS B SG  1 
ATOM   4213 N N   . VAL B 2 129 ? 171.175 157.626 203.981 1.00 11.05 ? 129 VAL B N   1 
ATOM   4214 C CA  . VAL B 2 129 ? 170.352 156.489 204.377 1.00 11.05 ? 129 VAL B CA  1 
ATOM   4215 C C   . VAL B 2 129 ? 170.829 155.211 203.696 1.00 11.05 ? 129 VAL B C   1 
ATOM   4216 O O   . VAL B 2 129 ? 170.783 154.132 204.299 1.00 11.05 ? 129 VAL B O   1 
ATOM   4217 C CB  . VAL B 2 129 ? 168.861 156.770 204.116 1.00 11.05 ? 129 VAL B CB  1 
ATOM   4218 C CG1 . VAL B 2 129 ? 168.557 156.825 202.642 1.00 11.05 ? 129 VAL B CG1 1 
ATOM   4219 C CG2 . VAL B 2 129 ? 168.017 155.720 204.788 1.00 11.05 ? 129 VAL B CG2 1 
ATOM   4220 N N   . LEU B 2 130 ? 171.320 155.296 202.456 1.00 10.66 ? 130 LEU B N   1 
ATOM   4221 C CA  . LEU B 2 130 ? 171.863 154.109 201.803 1.00 10.66 ? 130 LEU B CA  1 
ATOM   4222 C C   . LEU B 2 130 ? 173.072 153.574 202.557 1.00 10.66 ? 130 LEU B C   1 
ATOM   4223 O O   . LEU B 2 130 ? 173.181 152.368 202.804 1.00 10.66 ? 130 LEU B O   1 
ATOM   4224 C CB  . LEU B 2 130 ? 172.236 154.426 200.356 1.00 10.66 ? 130 LEU B CB  1 
ATOM   4225 C CG  . LEU B 2 130 ? 171.124 154.307 199.318 1.00 10.66 ? 130 LEU B CG  1 
ATOM   4226 C CD1 . LEU B 2 130 ? 171.708 154.298 197.925 1.00 10.66 ? 130 LEU B CD1 1 
ATOM   4227 C CD2 . LEU B 2 130 ? 170.311 153.059 199.565 1.00 10.66 ? 130 LEU B CD2 1 
ATOM   4228 N N   . TYR B 2 131 ? 173.991 154.460 202.941 1.00 9.78  ? 131 TYR B N   1 
ATOM   4229 C CA  . TYR B 2 131 ? 175.158 154.009 203.688 1.00 9.78  ? 131 TYR B CA  1 
ATOM   4230 C C   . TYR B 2 131 ? 174.756 153.411 205.024 1.00 9.78  ? 131 TYR B C   1 
ATOM   4231 O O   . TYR B 2 131 ? 175.259 152.351 205.412 1.00 9.78  ? 131 TYR B O   1 
ATOM   4232 C CB  . TYR B 2 131 ? 176.135 155.157 203.905 1.00 9.78  ? 131 TYR B CB  1 
ATOM   4233 C CG  . TYR B 2 131 ? 177.412 154.728 204.577 1.00 9.78  ? 131 TYR B CG  1 
ATOM   4234 C CD1 . TYR B 2 131 ? 178.032 153.544 204.229 1.00 9.78  ? 131 TYR B CD1 1 
ATOM   4235 C CD2 . TYR B 2 131 ? 178.002 155.510 205.550 1.00 9.78  ? 131 TYR B CD2 1 
ATOM   4236 C CE1 . TYR B 2 131 ? 179.200 153.148 204.836 1.00 9.78  ? 131 TYR B CE1 1 
ATOM   4237 C CE2 . TYR B 2 131 ? 179.170 155.121 206.161 1.00 9.78  ? 131 TYR B CE2 1 
ATOM   4238 C CZ  . TYR B 2 131 ? 179.765 153.939 205.801 1.00 9.78  ? 131 TYR B CZ  1 
ATOM   4239 O OH  . TYR B 2 131 ? 180.933 153.547 206.408 1.00 9.78  ? 131 TYR B OH  1 
ATOM   4240 N N   . LEU B 2 132 ? 173.844 154.069 205.742 1.00 21.39 ? 132 LEU B N   1 
ATOM   4241 C CA  . LEU B 2 132 ? 173.460 153.570 207.057 1.00 21.39 ? 132 LEU B CA  1 
ATOM   4242 C C   . LEU B 2 132 ? 172.786 152.212 206.956 1.00 21.39 ? 132 LEU B C   1 
ATOM   4243 O O   . LEU B 2 132 ? 173.030 151.330 207.784 1.00 21.39 ? 132 LEU B O   1 
ATOM   4244 C CB  . LEU B 2 132 ? 172.553 154.574 207.760 1.00 21.39 ? 132 LEU B CB  1 
ATOM   4245 C CG  . LEU B 2 132 ? 173.327 155.629 208.540 1.00 21.39 ? 132 LEU B CG  1 
ATOM   4246 C CD1 . LEU B 2 132 ? 172.399 156.665 209.114 1.00 21.39 ? 132 LEU B CD1 1 
ATOM   4247 C CD2 . LEU B 2 132 ? 174.119 154.965 209.630 1.00 21.39 ? 132 LEU B CD2 1 
ATOM   4248 N N   . TRP B 2 133 ? 171.953 152.005 205.937 1.00 13.66 ? 133 TRP B N   1 
ATOM   4249 C CA  . TRP B 2 133 ? 171.252 150.731 205.857 1.00 13.66 ? 133 TRP B CA  1 
ATOM   4250 C C   . TRP B 2 133 ? 172.134 149.616 205.318 1.00 13.66 ? 133 TRP B C   1 
ATOM   4251 O O   . TRP B 2 133 ? 171.969 148.464 205.724 1.00 13.66 ? 133 TRP B O   1 
ATOM   4252 C CB  . TRP B 2 133 ? 169.981 150.884 205.033 1.00 13.66 ? 133 TRP B CB  1 
ATOM   4253 C CG  . TRP B 2 133 ? 168.935 151.577 205.831 1.00 13.66 ? 133 TRP B CG  1 
ATOM   4254 C CD1 . TRP B 2 133 ? 169.108 152.200 207.032 1.00 13.66 ? 133 TRP B CD1 1 
ATOM   4255 C CD2 . TRP B 2 133 ? 167.557 151.719 205.506 1.00 13.66 ? 133 TRP B CD2 1 
ATOM   4256 N NE1 . TRP B 2 133 ? 167.924 152.728 207.470 1.00 13.66 ? 133 TRP B NE1 1 
ATOM   4257 C CE2 . TRP B 2 133 ? 166.954 152.444 206.550 1.00 13.66 ? 133 TRP B CE2 1 
ATOM   4258 C CE3 . TRP B 2 133 ? 166.773 151.308 204.434 1.00 13.66 ? 133 TRP B CE3 1 
ATOM   4259 C CZ2 . TRP B 2 133 ? 165.613 152.761 206.551 1.00 13.66 ? 133 TRP B CZ2 1 
ATOM   4260 C CZ3 . TRP B 2 133 ? 165.444 151.629 204.436 1.00 13.66 ? 133 TRP B CZ3 1 
ATOM   4261 C CH2 . TRP B 2 133 ? 164.873 152.345 205.487 1.00 13.66 ? 133 TRP B CH2 1 
ATOM   4262 N N   . ALA B 2 134 ? 173.093 149.917 204.442 1.00 13.61 ? 134 ALA B N   1 
ATOM   4263 C CA  . ALA B 2 134 ? 174.086 148.903 204.105 1.00 13.61 ? 134 ALA B CA  1 
ATOM   4264 C C   . ALA B 2 134 ? 174.895 148.509 205.335 1.00 13.61 ? 134 ALA B C   1 
ATOM   4265 O O   . ALA B 2 134 ? 175.135 147.319 205.580 1.00 13.61 ? 134 ALA B O   1 
ATOM   4266 C CB  . ALA B 2 134 ? 175.006 149.409 202.995 1.00 13.61 ? 134 ALA B CB  1 
ATOM   4267 N N   . LEU B 2 135 ? 175.304 149.495 206.134 1.00 9.76  ? 135 LEU B N   1 
ATOM   4268 C CA  . LEU B 2 135 ? 176.042 149.206 207.356 1.00 9.76  ? 135 LEU B CA  1 
ATOM   4269 C C   . LEU B 2 135 ? 175.202 148.411 208.347 1.00 9.76  ? 135 LEU B C   1 
ATOM   4270 O O   . LEU B 2 135 ? 175.742 147.608 209.114 1.00 9.76  ? 135 LEU B O   1 
ATOM   4271 C CB  . LEU B 2 135 ? 176.514 150.515 207.978 1.00 9.76  ? 135 LEU B CB  1 
ATOM   4272 C CG  . LEU B 2 135 ? 177.629 150.485 209.007 1.00 9.76  ? 135 LEU B CG  1 
ATOM   4273 C CD1 . LEU B 2 135 ? 178.772 149.643 208.513 1.00 9.76  ? 135 LEU B CD1 1 
ATOM   4274 C CD2 . LEU B 2 135 ? 178.080 151.902 209.233 1.00 9.76  ? 135 LEU B CD2 1 
ATOM   4275 N N   . LYS B 2 136 ? 173.886 148.633 208.361 1.00 9.44  ? 136 LYS B N   1 
ATOM   4276 C CA  . LYS B 2 136 ? 173.010 147.823 209.202 1.00 9.44  ? 136 LYS B CA  1 
ATOM   4277 C C   . LYS B 2 136 ? 172.886 146.403 208.662 1.00 9.44  ? 136 LYS B C   1 
ATOM   4278 O O   . LYS B 2 136 ? 172.812 145.445 209.439 1.00 9.44  ? 136 LYS B O   1 
ATOM   4279 C CB  . LYS B 2 136 ? 171.635 148.480 209.316 1.00 9.44  ? 136 LYS B CB  1 
ATOM   4280 C CG  . LYS B 2 136 ? 170.579 147.619 209.979 1.00 9.44  ? 136 LYS B CG  1 
ATOM   4281 C CD  . LYS B 2 136 ? 170.850 147.436 211.454 1.00 9.44  ? 136 LYS B CD  1 
ATOM   4282 C CE  . LYS B 2 136 ? 169.579 147.099 212.201 1.00 9.44  ? 136 LYS B CE  1 
ATOM   4283 N NZ  . LYS B 2 136 ? 169.850 146.513 213.534 1.00 9.44  ? 136 LYS B NZ  1 
ATOM   4284 N N   . ILE B 2 137 ? 172.857 146.247 207.337 1.00 12.74 ? 137 ILE B N   1 
ATOM   4285 C CA  . ILE B 2 137 ? 172.796 144.911 206.745 1.00 12.74 ? 137 ILE B CA  1 
ATOM   4286 C C   . ILE B 2 137 ? 174.028 144.107 207.128 1.00 12.74 ? 137 ILE B C   1 
ATOM   4287 O O   . ILE B 2 137 ? 173.932 142.943 207.533 1.00 12.74 ? 137 ILE B O   1 
ATOM   4288 C CB  . ILE B 2 137 ? 172.653 145.000 205.217 1.00 12.74 ? 137 ILE B CB  1 
ATOM   4289 C CG1 . ILE B 2 137 ? 171.280 145.526 204.842 1.00 12.74 ? 137 ILE B CG1 1 
ATOM   4290 C CG2 . ILE B 2 137 ? 172.849 143.634 204.597 1.00 12.74 ? 137 ILE B CG2 1 
ATOM   4291 C CD1 . ILE B 2 137 ? 170.186 144.675 205.361 1.00 12.74 ? 137 ILE B CD1 1 
ATOM   4292 N N   . LEU B 2 138 ? 175.208 144.712 206.997 1.00 11.44 ? 138 LEU B N   1 
ATOM   4293 C CA  . LEU B 2 138 ? 176.432 143.974 207.284 1.00 11.44 ? 138 LEU B CA  1 
ATOM   4294 C C   . LEU B 2 138 ? 176.528 143.648 208.772 1.00 11.44 ? 138 LEU B C   1 
ATOM   4295 O O   . LEU B 2 138 ? 176.813 142.506 209.146 1.00 11.44 ? 138 LEU B O   1 
ATOM   4296 C CB  . LEU B 2 138 ? 177.647 144.773 206.812 1.00 11.44 ? 138 LEU B CB  1 
ATOM   4297 C CG  . LEU B 2 138 ? 179.028 144.112 206.839 1.00 11.44 ? 138 LEU B CG  1 
ATOM   4298 C CD1 . LEU B 2 138 ? 179.925 144.746 205.791 1.00 11.44 ? 138 LEU B CD1 1 
ATOM   4299 C CD2 . LEU B 2 138 ? 179.701 144.154 208.186 1.00 11.44 ? 138 LEU B CD2 1 
ATOM   4300 N N   . TYR B 2 139 ? 176.278 144.638 209.637 1.00 10.40 ? 139 TYR B N   1 
ATOM   4301 C CA  . TYR B 2 139 ? 176.307 144.457 211.088 1.00 10.40 ? 139 TYR B CA  1 
ATOM   4302 C C   . TYR B 2 139 ? 174.889 144.520 211.632 1.00 10.40 ? 139 TYR B C   1 
ATOM   4303 O O   . TYR B 2 139 ? 174.332 145.618 211.773 1.00 10.40 ? 139 TYR B O   1 
ATOM   4304 C CB  . TYR B 2 139 ? 177.171 145.525 211.762 1.00 10.40 ? 139 TYR B CB  1 
ATOM   4305 C CG  . TYR B 2 139 ? 178.643 145.467 211.445 1.00 10.40 ? 139 TYR B CG  1 
ATOM   4306 C CD1 . TYR B 2 139 ? 179.257 146.475 210.719 1.00 10.40 ? 139 TYR B CD1 1 
ATOM   4307 C CD2 . TYR B 2 139 ? 179.421 144.403 211.870 1.00 10.40 ? 139 TYR B CD2 1 
ATOM   4308 C CE1 . TYR B 2 139 ? 180.606 146.431 210.435 1.00 10.40 ? 139 TYR B CE1 1 
ATOM   4309 C CE2 . TYR B 2 139 ? 180.768 144.345 211.582 1.00 10.40 ? 139 TYR B CE2 1 
ATOM   4310 C CZ  . TYR B 2 139 ? 181.354 145.360 210.865 1.00 10.40 ? 139 TYR B CZ  1 
ATOM   4311 O OH  . TYR B 2 139 ? 182.695 145.300 210.581 1.00 10.40 ? 139 TYR B OH  1 
ATOM   4312 N N   . PRO B 2 140 ? 174.266 143.395 211.969 1.00 9.49  ? 140 PRO B N   1 
ATOM   4313 C CA  . PRO B 2 140 ? 172.850 143.430 212.355 1.00 9.49  ? 140 PRO B CA  1 
ATOM   4314 C C   . PRO B 2 140 ? 172.596 143.577 213.847 1.00 9.49  ? 140 PRO B C   1 
ATOM   4315 O O   . PRO B 2 140 ? 171.490 143.951 214.243 1.00 9.49  ? 140 PRO B O   1 
ATOM   4316 C CB  . PRO B 2 140 ? 172.329 142.086 211.840 1.00 9.49  ? 140 PRO B CB  1 
ATOM   4317 C CG  . PRO B 2 140 ? 173.530 141.177 211.870 1.00 9.49  ? 140 PRO B CG  1 
ATOM   4318 C CD  . PRO B 2 140 ? 174.783 142.020 211.911 1.00 9.49  ? 140 PRO B CD  1 
ATOM   4319 N N   . LYS B 2 141 ? 173.594 143.302 214.685 1.00 9.68  ? 141 LYS B N   1 
ATOM   4320 C CA  . LYS B 2 141 ? 173.411 143.328 216.133 1.00 9.68  ? 141 LYS B CA  1 
ATOM   4321 C C   . LYS B 2 141 ? 174.399 144.260 216.821 1.00 9.68  ? 141 LYS B C   1 
ATOM   4322 O O   . LYS B 2 141 ? 174.640 144.121 218.023 1.00 9.68  ? 141 LYS B O   1 
ATOM   4323 C CB  . LYS B 2 141 ? 173.534 141.921 216.719 1.00 9.68  ? 141 LYS B CB  1 
ATOM   4324 C CG  . LYS B 2 141 ? 172.399 140.967 216.369 1.00 9.68  ? 141 LYS B CG  1 
ATOM   4325 C CD  . LYS B 2 141 ? 171.046 141.656 216.364 1.00 9.68  ? 141 LYS B CD  1 
ATOM   4326 C CE  . LYS B 2 141 ? 169.931 140.687 216.729 1.00 9.68  ? 141 LYS B CE  1 
ATOM   4327 N NZ  . LYS B 2 141 ? 168.591 141.200 216.334 1.00 9.68  ? 141 LYS B NZ  1 
ATOM   4328 N N   . THR B 2 142 ? 174.986 145.201 216.080 1.00 14.80 ? 142 THR B N   1 
ATOM   4329 C CA  . THR B 2 142 ? 176.006 146.085 216.630 1.00 14.80 ? 142 THR B CA  1 
ATOM   4330 C C   . THR B 2 142 ? 175.806 147.513 216.121 1.00 14.80 ? 142 THR B C   1 
ATOM   4331 O O   . THR B 2 142 ? 176.714 148.340 216.224 1.00 14.80 ? 142 THR B O   1 
ATOM   4332 C CB  . THR B 2 142 ? 177.404 145.521 216.287 1.00 14.80 ? 142 THR B CB  1 
ATOM   4333 O OG1 . THR B 2 142 ? 177.478 144.166 216.744 1.00 14.80 ? 142 THR B OG1 1 
ATOM   4334 C CG2 . THR B 2 142 ? 178.524 146.271 216.981 1.00 14.80 ? 142 THR B CG2 1 
ATOM   4335 N N   . LEU B 2 143 ? 174.634 147.823 215.568 1.00 13.06 ? 143 LEU B N   1 
ATOM   4336 C CA  . LEU B 2 143 ? 174.327 149.192 215.164 1.00 13.06 ? 143 LEU B CA  1 
ATOM   4337 C C   . LEU B 2 143 ? 172.806 149.316 215.157 1.00 13.06 ? 143 LEU B C   1 
ATOM   4338 O O   . LEU B 2 143 ? 172.153 148.795 214.251 1.00 13.06 ? 143 LEU B O   1 
ATOM   4339 C CB  . LEU B 2 143 ? 174.925 149.514 213.805 1.00 13.06 ? 143 LEU B CB  1 
ATOM   4340 C CG  . LEU B 2 143 ? 174.892 150.967 213.339 1.00 13.06 ? 143 LEU B CG  1 
ATOM   4341 C CD1 . LEU B 2 143 ? 176.100 151.254 212.500 1.00 13.06 ? 143 LEU B CD1 1 
ATOM   4342 C CD2 . LEU B 2 143 ? 173.654 151.246 212.539 1.00 13.06 ? 143 LEU B CD2 1 
ATOM   4343 N N   . PHE B 2 144 ? 172.256 149.993 216.159 1.00 21.39 ? 144 PHE B N   1 
ATOM   4344 C CA  . PHE B 2 144 ? 170.814 150.093 216.316 1.00 21.39 ? 144 PHE B CA  1 
ATOM   4345 C C   . PHE B 2 144 ? 170.314 151.448 215.835 1.00 21.39 ? 144 PHE B C   1 
ATOM   4346 O O   . PHE B 2 144 ? 170.913 152.483 216.134 1.00 21.39 ? 144 PHE B O   1 
ATOM   4347 C CB  . PHE B 2 144 ? 170.418 149.878 217.773 1.00 21.39 ? 144 PHE B CB  1 
ATOM   4348 C CG  . PHE B 2 144 ? 170.831 148.548 218.322 1.00 21.39 ? 144 PHE B CG  1 
ATOM   4349 C CD1 . PHE B 2 144 ? 171.831 148.456 219.262 1.00 21.39 ? 144 PHE B CD1 1 
ATOM   4350 C CD2 . PHE B 2 144 ? 170.210 147.393 217.905 1.00 21.39 ? 144 PHE B CD2 1 
ATOM   4351 C CE1 . PHE B 2 144 ? 172.208 147.240 219.767 1.00 21.39 ? 144 PHE B CE1 1 
ATOM   4352 C CE2 . PHE B 2 144 ? 170.584 146.174 218.412 1.00 21.39 ? 144 PHE B CE2 1 
ATOM   4353 C CZ  . PHE B 2 144 ? 171.584 146.098 219.342 1.00 21.39 ? 144 PHE B CZ  1 
ATOM   4354 N N   . LEU B 2 145 ? 169.216 151.432 215.085 1.00 13.18 ? 145 LEU B N   1 
ATOM   4355 C CA  . LEU B 2 145 ? 168.599 152.635 214.550 1.00 13.18 ? 145 LEU B CA  1 
ATOM   4356 C C   . LEU B 2 145 ? 167.239 152.866 215.198 1.00 13.18 ? 145 LEU B C   1 
ATOM   4357 O O   . LEU B 2 145 ? 166.529 151.917 215.533 1.00 13.18 ? 145 LEU B O   1 
ATOM   4358 C CB  . LEU B 2 145 ? 168.433 152.539 213.030 1.00 13.18 ? 145 LEU B CB  1 
ATOM   4359 C CG  . LEU B 2 145 ? 169.682 152.355 212.169 1.00 13.18 ? 145 LEU B CG  1 
ATOM   4360 C CD1 . LEU B 2 145 ? 169.321 152.338 210.703 1.00 13.18 ? 145 LEU B CD1 1 
ATOM   4361 C CD2 . LEU B 2 145 ? 170.659 153.457 212.441 1.00 13.18 ? 145 LEU B CD2 1 
ATOM   4362 N N   . LEU B 2 146 ? 166.890 154.137 215.384 1.00 21.39 ? 146 LEU B N   1 
ATOM   4363 C CA  . LEU B 2 146 ? 165.602 154.582 215.916 1.00 21.39 ? 146 LEU B CA  1 
ATOM   4364 C C   . LEU B 2 146 ? 164.894 155.459 214.891 1.00 21.39 ? 146 LEU B C   1 
ATOM   4365 O O   . LEU B 2 146 ? 165.394 155.694 213.791 1.00 21.39 ? 146 LEU B O   1 
ATOM   4366 C CB  . LEU B 2 146 ? 165.769 155.333 217.240 1.00 21.39 ? 146 LEU B CB  1 
ATOM   4367 C CG  . LEU B 2 146 ? 165.879 154.561 218.551 1.00 21.39 ? 146 LEU B CG  1 
ATOM   4368 C CD1 . LEU B 2 146 ? 164.605 153.834 218.806 1.00 21.39 ? 146 LEU B CD1 1 
ATOM   4369 C CD2 . LEU B 2 146 ? 166.962 153.553 218.449 1.00 21.39 ? 146 LEU B CD2 1 
ATOM   4370 N N   . ARG B 2 147 ? 163.721 155.954 215.272 1.00 14.08 ? 147 ARG B N   1 
ATOM   4371 C CA  . ARG B 2 147 ? 162.825 156.656 214.366 1.00 14.08 ? 147 ARG B CA  1 
ATOM   4372 C C   . ARG B 2 147 ? 162.577 158.075 214.850 1.00 14.08 ? 147 ARG B C   1 
ATOM   4373 O O   . ARG B 2 147 ? 162.359 158.302 216.042 1.00 14.08 ? 147 ARG B O   1 
ATOM   4374 C CB  . ARG B 2 147 ? 161.495 155.926 214.246 1.00 14.08 ? 147 ARG B CB  1 
ATOM   4375 C CG  . ARG B 2 147 ? 160.475 156.660 213.419 1.00 14.08 ? 147 ARG B CG  1 
ATOM   4376 C CD  . ARG B 2 147 ? 159.410 155.728 212.922 1.00 14.08 ? 147 ARG B CD  1 
ATOM   4377 N NE  . ARG B 2 147 ? 158.742 156.270 211.752 1.00 14.08 ? 147 ARG B NE  1 
ATOM   4378 C CZ  . ARG B 2 147 ? 157.632 155.761 211.241 1.00 14.08 ? 147 ARG B CZ  1 
ATOM   4379 N NH1 . ARG B 2 147 ? 157.074 154.700 211.803 1.00 14.08 ? 147 ARG B NH1 1 
ATOM   4380 N NH2 . ARG B 2 147 ? 157.079 156.313 210.172 1.00 14.08 ? 147 ARG B NH2 1 
ATOM   4381 N N   . GLY B 2 148 ? 162.590 159.028 213.913 1.00 14.52 ? 148 GLY B N   1 
ATOM   4382 C CA  . GLY B 2 148 ? 162.372 160.422 214.223 1.00 14.52 ? 148 GLY B CA  1 
ATOM   4383 C C   . GLY B 2 148 ? 161.148 160.976 213.510 1.00 14.52 ? 148 GLY B C   1 
ATOM   4384 O O   . GLY B 2 148 ? 160.502 160.297 212.710 1.00 14.52 ? 148 GLY B O   1 
ATOM   4385 N N   . ASN B 2 149 ? 160.843 162.239 213.810 1.00 11.23 ? 149 ASN B N   1 
ATOM   4386 C CA  . ASN B 2 149 ? 159.644 162.860 213.265 1.00 11.23 ? 149 ASN B CA  1 
ATOM   4387 C C   . ASN B 2 149 ? 159.743 163.137 211.773 1.00 11.23 ? 149 ASN B C   1 
ATOM   4388 O O   . ASN B 2 149 ? 158.708 163.199 211.105 1.00 11.23 ? 149 ASN B O   1 
ATOM   4389 C CB  . ASN B 2 149 ? 159.331 164.153 214.016 1.00 11.23 ? 149 ASN B CB  1 
ATOM   4390 C CG  . ASN B 2 149 ? 160.538 165.048 214.166 1.00 11.23 ? 149 ASN B CG  1 
ATOM   4391 O OD1 . ASN B 2 149 ? 161.650 164.667 213.822 1.00 11.23 ? 149 ASN B OD1 1 
ATOM   4392 N ND2 . ASN B 2 149 ? 160.324 166.245 214.690 1.00 11.23 ? 149 ASN B ND2 1 
ATOM   4393 N N   . HIS B 2 150 ? 160.947 163.286 211.228 1.00 11.49 ? 150 HIS B N   1 
ATOM   4394 C CA  . HIS B 2 150 ? 161.121 163.610 209.816 1.00 11.49 ? 150 HIS B CA  1 
ATOM   4395 C C   . HIS B 2 150 ? 161.075 162.400 208.910 1.00 11.49 ? 150 HIS B C   1 
ATOM   4396 O O   . HIS B 2 150 ? 161.614 162.455 207.804 1.00 11.49 ? 150 HIS B O   1 
ATOM   4397 C CB  . HIS B 2 150 ? 162.431 164.363 209.593 1.00 11.49 ? 150 HIS B CB  1 
ATOM   4398 C CG  . HIS B 2 150 ? 162.300 165.845 209.715 1.00 11.49 ? 150 HIS B CG  1 
ATOM   4399 N ND1 . HIS B 2 150 ? 161.735 166.618 208.728 1.00 11.49 ? 150 HIS B ND1 1 
ATOM   4400 C CD2 . HIS B 2 150 ? 162.645 166.696 210.708 1.00 11.49 ? 150 HIS B CD2 1 
ATOM   4401 C CE1 . HIS B 2 150 ? 161.745 167.884 209.103 1.00 11.49 ? 150 HIS B CE1 1 
ATOM   4402 N NE2 . HIS B 2 150 ? 162.291 167.958 210.302 1.00 11.49 ? 150 HIS B NE2 1 
ATOM   4403 N N   . GLU B 2 151 ? 160.446 161.316 209.333 1.00 18.43 ? 151 GLU B N   1 
ATOM   4404 C CA  . GLU B 2 151 ? 160.427 160.072 208.580 1.00 18.43 ? 151 GLU B CA  1 
ATOM   4405 C C   . GLU B 2 151 ? 158.998 159.655 208.256 1.00 18.43 ? 151 GLU B C   1 
ATOM   4406 O O   . GLU B 2 151 ? 158.617 158.493 208.403 1.00 18.43 ? 151 GLU B O   1 
ATOM   4407 C CB  . GLU B 2 151 ? 161.167 158.996 209.360 1.00 18.43 ? 151 GLU B CB  1 
ATOM   4408 C CG  . GLU B 2 151 ? 162.641 159.304 209.466 1.00 18.43 ? 151 GLU B CG  1 
ATOM   4409 C CD  . GLU B 2 151 ? 163.384 158.271 210.255 1.00 18.43 ? 151 GLU B CD  1 
ATOM   4410 O OE1 . GLU B 2 151 ? 162.725 157.383 210.825 1.00 18.43 ? 151 GLU B OE1 1 
ATOM   4411 O OE2 . GLU B 2 151 ? 164.623 158.344 210.316 1.00 18.43 ? 151 GLU B OE2 1 
ATOM   4412 N N   . CYS B 2 152 ? 158.194 160.615 207.812 1.00 15.27 ? 152 CYS B N   1 
ATOM   4413 C CA  . CYS B 2 152 ? 156.788 160.431 207.501 1.00 15.27 ? 152 CYS B CA  1 
ATOM   4414 C C   . CYS B 2 152 ? 156.540 160.746 206.028 1.00 15.27 ? 152 CYS B C   1 
ATOM   4415 O O   . CYS B 2 152 ? 157.474 160.955 205.247 1.00 15.27 ? 152 CYS B O   1 
ATOM   4416 C CB  . CYS B 2 152 ? 155.935 161.313 208.411 1.00 15.27 ? 152 CYS B CB  1 
ATOM   4417 S SG  . CYS B 2 152 ? 156.320 161.175 210.164 1.00 15.27 ? 152 CYS B SG  1 
ATOM   4418 N N   . ARG B 2 153 ? 155.265 160.774 205.645 1.00 25.75 ? 153 ARG B N   1 
ATOM   4419 C CA  . ARG B 2 153 ? 154.887 161.192 204.303 1.00 25.75 ? 153 ARG B CA  1 
ATOM   4420 C C   . ARG B 2 153 ? 154.584 162.680 204.210 1.00 25.75 ? 153 ARG B C   1 
ATOM   4421 O O   . ARG B 2 153 ? 154.611 163.235 203.106 1.00 25.75 ? 153 ARG B O   1 
ATOM   4422 C CB  . ARG B 2 153 ? 153.666 160.403 203.822 1.00 25.75 ? 153 ARG B CB  1 
ATOM   4423 C CG  . ARG B 2 153 ? 153.988 159.201 202.953 1.00 25.75 ? 153 ARG B CG  1 
ATOM   4424 C CD  . ARG B 2 153 ? 154.659 158.095 203.750 1.00 25.75 ? 153 ARG B CD  1 
ATOM   4425 N NE  . ARG B 2 153 ? 154.678 156.832 203.018 1.00 25.75 ? 153 ARG B NE  1 
ATOM   4426 C CZ  . ARG B 2 153 ? 153.762 155.879 203.151 1.00 25.75 ? 153 ARG B CZ  1 
ATOM   4427 N NH1 . ARG B 2 153 ? 152.752 156.041 203.993 1.00 25.75 ? 153 ARG B NH1 1 
ATOM   4428 N NH2 . ARG B 2 153 ? 153.855 154.764 202.443 1.00 25.75 ? 153 ARG B NH2 1 
ATOM   4429 N N   . HIS B 2 154 ? 154.292 163.337 205.334 1.00 25.49 ? 154 HIS B N   1 
ATOM   4430 C CA  . HIS B 2 154 ? 153.999 164.767 205.318 1.00 25.49 ? 154 HIS B CA  1 
ATOM   4431 C C   . HIS B 2 154 ? 155.283 165.587 205.307 1.00 25.49 ? 154 HIS B C   1 
ATOM   4432 O O   . HIS B 2 154 ? 155.490 166.422 204.421 1.00 25.49 ? 154 HIS B O   1 
ATOM   4433 C CB  . HIS B 2 154 ? 153.144 165.151 206.529 1.00 25.49 ? 154 HIS B CB  1 
ATOM   4434 C CG  . HIS B 2 154 ? 152.076 164.158 206.861 1.00 25.49 ? 154 HIS B CG  1 
ATOM   4435 N ND1 . HIS B 2 154 ? 152.042 163.476 208.059 1.00 25.49 ? 154 HIS B ND1 1 
ATOM   4436 C CD2 . HIS B 2 154 ? 151.002 163.730 206.156 1.00 25.49 ? 154 HIS B CD2 1 
ATOM   4437 C CE1 . HIS B 2 154 ? 150.993 162.673 208.077 1.00 25.49 ? 154 HIS B CE1 1 
ATOM   4438 N NE2 . HIS B 2 154 ? 150.346 162.807 206.934 1.00 25.49 ? 154 HIS B NE2 1 
ATOM   4439 N N   . LEU B 2 155 ? 156.155 165.358 206.292 1.00 15.25 ? 155 LEU B N   1 
ATOM   4440 C CA  . LEU B 2 155 ? 157.350 166.182 206.447 1.00 15.25 ? 155 LEU B CA  1 
ATOM   4441 C C   . LEU B 2 155 ? 158.275 166.053 205.245 1.00 15.25 ? 155 LEU B C   1 
ATOM   4442 O O   . LEU B 2 155 ? 158.792 167.053 204.737 1.00 15.25 ? 155 LEU B O   1 
ATOM   4443 C CB  . LEU B 2 155 ? 158.094 165.796 207.724 1.00 15.25 ? 155 LEU B CB  1 
ATOM   4444 C CG  . LEU B 2 155 ? 157.647 166.369 209.069 1.00 15.25 ? 155 LEU B CG  1 
ATOM   4445 C CD1 . LEU B 2 155 ? 157.764 167.880 209.073 1.00 15.25 ? 155 LEU B CD1 1 
ATOM   4446 C CD2 . LEU B 2 155 ? 156.246 165.922 209.443 1.00 15.25 ? 155 LEU B CD2 1 
ATOM   4447 N N   . THR B 2 156 ? 158.504 164.825 204.780 1.00 17.71 ? 156 THR B N   1 
ATOM   4448 C CA  . THR B 2 156 ? 159.460 164.613 203.698 1.00 17.71 ? 156 THR B CA  1 
ATOM   4449 C C   . THR B 2 156 ? 158.969 165.213 202.387 1.00 17.71 ? 156 THR B C   1 
ATOM   4450 O O   . THR B 2 156 ? 159.749 165.825 201.651 1.00 17.71 ? 156 THR B O   1 
ATOM   4451 C CB  . THR B 2 156 ? 159.741 163.127 203.530 1.00 17.71 ? 156 THR B CB  1 
ATOM   4452 O OG1 . THR B 2 156 ? 158.508 162.402 203.577 1.00 17.71 ? 156 THR B OG1 1 
ATOM   4453 C CG2 . THR B 2 156 ? 160.655 162.639 204.634 1.00 17.71 ? 156 THR B CG2 1 
ATOM   4454 N N   . GLU B 2 157 ? 157.686 165.039 202.067 1.00 17.29 ? 157 GLU B N   1 
ATOM   4455 C CA  . GLU B 2 157 ? 157.141 165.695 200.884 1.00 17.29 ? 157 GLU B CA  1 
ATOM   4456 C C   . GLU B 2 157 ? 157.192 167.208 201.035 1.00 17.29 ? 157 GLU B C   1 
ATOM   4457 O O   . GLU B 2 157 ? 157.491 167.928 200.076 1.00 17.29 ? 157 GLU B O   1 
ATOM   4458 C CB  . GLU B 2 157 ? 155.709 165.228 200.631 1.00 17.29 ? 157 GLU B CB  1 
ATOM   4459 N N   . TYR B 2 158 ? 156.904 167.705 202.237 1.00 17.72 ? 158 TYR B N   1 
ATOM   4460 C CA  . TYR B 2 158 ? 156.976 169.137 202.495 1.00 17.72 ? 158 TYR B CA  1 
ATOM   4461 C C   . TYR B 2 158 ? 158.395 169.657 202.311 1.00 17.72 ? 158 TYR B C   1 
ATOM   4462 O O   . TYR B 2 158 ? 158.603 170.707 201.695 1.00 17.72 ? 158 TYR B O   1 
ATOM   4463 C CB  . TYR B 2 158 ? 156.463 169.414 203.909 1.00 17.72 ? 158 TYR B CB  1 
ATOM   4464 C CG  . TYR B 2 158 ? 156.434 170.859 204.346 1.00 17.72 ? 158 TYR B CG  1 
ATOM   4465 C CD1 . TYR B 2 158 ? 156.394 171.892 203.427 1.00 17.72 ? 158 TYR B CD1 1 
ATOM   4466 C CD2 . TYR B 2 158 ? 156.429 171.183 205.691 1.00 17.72 ? 158 TYR B CD2 1 
ATOM   4467 C CE1 . TYR B 2 158 ? 156.368 173.206 203.838 1.00 17.72 ? 158 TYR B CE1 1 
ATOM   4468 C CE2 . TYR B 2 158 ? 156.400 172.489 206.110 1.00 17.72 ? 158 TYR B CE2 1 
ATOM   4469 C CZ  . TYR B 2 158 ? 156.369 173.498 205.182 1.00 17.72 ? 158 TYR B CZ  1 
ATOM   4470 O OH  . TYR B 2 158 ? 156.340 174.805 205.606 1.00 17.72 ? 158 TYR B OH  1 
ATOM   4471 N N   . PHE B 2 159 ? 159.383 168.930 202.817 1.00 14.54 ? 159 PHE B N   1 
ATOM   4472 C CA  . PHE B 2 159 ? 160.773 169.357 202.756 1.00 14.54 ? 159 PHE B CA  1 
ATOM   4473 C C   . PHE B 2 159 ? 161.425 168.801 201.489 1.00 14.54 ? 159 PHE B C   1 
ATOM   4474 O O   . PHE B 2 159 ? 160.740 168.346 200.570 1.00 14.54 ? 159 PHE B O   1 
ATOM   4475 C CB  . PHE B 2 159 ? 161.500 168.951 204.038 1.00 14.54 ? 159 PHE B CB  1 
ATOM   4476 C CG  . PHE B 2 159 ? 161.318 169.923 205.158 1.00 14.54 ? 159 PHE B CG  1 
ATOM   4477 C CD1 . PHE B 2 159 ? 160.714 169.539 206.334 1.00 14.54 ? 159 PHE B CD1 1 
ATOM   4478 C CD2 . PHE B 2 159 ? 161.732 171.230 205.023 1.00 14.54 ? 159 PHE B CD2 1 
ATOM   4479 C CE1 . PHE B 2 159 ? 160.541 170.437 207.361 1.00 14.54 ? 159 PHE B CE1 1 
ATOM   4480 C CE2 . PHE B 2 159 ? 161.560 172.130 206.047 1.00 14.54 ? 159 PHE B CE2 1 
ATOM   4481 C CZ  . PHE B 2 159 ? 160.964 171.732 207.217 1.00 14.54 ? 159 PHE B CZ  1 
ATOM   4482 N N   . THR B 2 160 ? 162.753 168.840 201.423 1.00 20.59 ? 160 THR B N   1 
ATOM   4483 C CA  . THR B 2 160 ? 163.500 168.594 200.192 1.00 20.59 ? 160 THR B CA  1 
ATOM   4484 C C   . THR B 2 160 ? 163.995 167.158 200.072 1.00 20.59 ? 160 THR B C   1 
ATOM   4485 O O   . THR B 2 160 ? 165.103 166.922 199.586 1.00 20.59 ? 160 THR B O   1 
ATOM   4486 C CB  . THR B 2 160 ? 164.668 169.573 200.085 1.00 20.59 ? 160 THR B CB  1 
ATOM   4487 O OG1 . THR B 2 160 ? 165.397 169.327 198.876 1.00 20.59 ? 160 THR B OG1 1 
ATOM   4488 C CG2 . THR B 2 160 ? 165.602 169.449 201.282 1.00 20.59 ? 160 THR B CG2 1 
ATOM   4489 N N   . PHE B 2 161 ? 163.212 166.171 200.502 1.00 15.77 ? 161 PHE B N   1 
ATOM   4490 C CA  . PHE B 2 161 ? 163.586 164.784 200.256 1.00 15.77 ? 161 PHE B CA  1 
ATOM   4491 C C   . PHE B 2 161 ? 162.895 164.182 199.043 1.00 15.77 ? 161 PHE B C   1 
ATOM   4492 O O   . PHE B 2 161 ? 163.542 163.482 198.263 1.00 15.77 ? 161 PHE B O   1 
ATOM   4493 C CB  . PHE B 2 161 ? 163.294 163.909 201.475 1.00 15.77 ? 161 PHE B CB  1 
ATOM   4494 C CG  . PHE B 2 161 ? 163.738 162.484 201.307 1.00 15.77 ? 161 PHE B CG  1 
ATOM   4495 C CD1 . PHE B 2 161 ? 162.928 161.440 201.698 1.00 15.77 ? 161 PHE B CD1 1 
ATOM   4496 C CD2 . PHE B 2 161 ? 164.960 162.191 200.746 1.00 15.77 ? 161 PHE B CD2 1 
ATOM   4497 C CE1 . PHE B 2 161 ? 163.334 160.138 201.538 1.00 15.77 ? 161 PHE B CE1 1 
ATOM   4498 C CE2 . PHE B 2 161 ? 165.365 160.891 200.588 1.00 15.77 ? 161 PHE B CE2 1 
ATOM   4499 C CZ  . PHE B 2 161 ? 164.552 159.866 200.983 1.00 15.77 ? 161 PHE B CZ  1 
ATOM   4500 N N   . LYS B 2 162 ? 161.596 164.426 198.861 1.00 23.84 ? 162 LYS B N   1 
ATOM   4501 C CA  . LYS B 2 162 ? 160.905 163.854 197.711 1.00 23.84 ? 162 LYS B CA  1 
ATOM   4502 C C   . LYS B 2 162 ? 161.508 164.354 196.406 1.00 23.84 ? 162 LYS B C   1 
ATOM   4503 O O   . LYS B 2 162 ? 161.728 163.572 195.474 1.00 23.84 ? 162 LYS B O   1 
ATOM   4504 C CB  . LYS B 2 162 ? 159.415 164.182 197.773 1.00 23.84 ? 162 LYS B CB  1 
ATOM   4505 C CG  . LYS B 2 162 ? 158.640 163.758 196.539 1.00 23.84 ? 162 LYS B CG  1 
ATOM   4506 C CD  . LYS B 2 162 ? 157.177 164.163 196.631 1.00 23.84 ? 162 LYS B CD  1 
ATOM   4507 C CE  . LYS B 2 162 ? 156.449 163.912 195.320 1.00 23.84 ? 162 LYS B CE  1 
ATOM   4508 N NZ  . LYS B 2 162 ? 155.524 162.752 195.413 1.00 23.84 ? 162 LYS B NZ  1 
ATOM   4509 N N   . GLN B 2 163 ? 161.798 165.654 196.328 1.00 21.82 ? 163 GLN B N   1 
ATOM   4510 C CA  . GLN B 2 163 ? 162.485 166.193 195.160 1.00 21.82 ? 163 GLN B CA  1 
ATOM   4511 C C   . GLN B 2 163 ? 163.873 165.591 195.005 1.00 21.82 ? 163 GLN B C   1 
ATOM   4512 O O   . GLN B 2 163 ? 164.332 165.367 193.880 1.00 21.82 ? 163 GLN B O   1 
ATOM   4513 C CB  . GLN B 2 163 ? 162.572 167.715 195.266 1.00 21.82 ? 163 GLN B CB  1 
ATOM   4514 C CG  . GLN B 2 163 ? 163.316 168.382 194.129 1.00 21.82 ? 163 GLN B CG  1 
ATOM   4515 C CD  . GLN B 2 163 ? 162.517 168.415 192.847 1.00 21.82 ? 163 GLN B CD  1 
ATOM   4516 O OE1 . GLN B 2 163 ? 161.299 168.254 192.857 1.00 21.82 ? 163 GLN B OE1 1 
ATOM   4517 N NE2 . GLN B 2 163 ? 163.200 168.636 191.731 1.00 21.82 ? 163 GLN B NE2 1 
ATOM   4518 N N   . GLU B 2 164 ? 164.551 165.317 196.120 1.00 18.94 ? 164 GLU B N   1 
ATOM   4519 C CA  . GLU B 2 164 ? 165.881 164.722 196.063 1.00 18.94 ? 164 GLU B CA  1 
ATOM   4520 C C   . GLU B 2 164 ? 165.842 163.355 195.393 1.00 18.94 ? 164 GLU B C   1 
ATOM   4521 O O   . GLU B 2 164 ? 166.626 163.074 194.477 1.00 18.94 ? 164 GLU B O   1 
ATOM   4522 C CB  . GLU B 2 164 ? 166.450 164.617 197.477 1.00 18.94 ? 164 GLU B CB  1 
ATOM   4523 C CG  . GLU B 2 164 ? 167.953 164.688 197.571 1.00 18.94 ? 164 GLU B CG  1 
ATOM   4524 C CD  . GLU B 2 164 ? 168.598 163.364 197.295 1.00 18.94 ? 164 GLU B CD  1 
ATOM   4525 O OE1 . GLU B 2 164 ? 167.888 162.343 197.371 1.00 18.94 ? 164 GLU B OE1 1 
ATOM   4526 O OE2 . GLU B 2 164 ? 169.812 163.341 197.015 1.00 18.94 ? 164 GLU B OE2 1 
ATOM   4527 N N   . CYS B 2 165 ? 164.929 162.489 195.835 1.00 24.42 ? 165 CYS B N   1 
ATOM   4528 C CA  . CYS B 2 165 ? 164.795 161.178 195.212 1.00 24.42 ? 165 CYS B CA  1 
ATOM   4529 C C   . CYS B 2 165 ? 164.324 161.301 193.772 1.00 24.42 ? 165 CYS B C   1 
ATOM   4530 O O   . CYS B 2 165 ? 164.761 160.539 192.906 1.00 24.42 ? 165 CYS B O   1 
ATOM   4531 C CB  . CYS B 2 165 ? 163.834 160.301 196.009 1.00 24.42 ? 165 CYS B CB  1 
ATOM   4532 S SG  . CYS B 2 165 ? 164.547 159.572 197.486 1.00 24.42 ? 165 CYS B SG  1 
ATOM   4533 N N   . LYS B 2 166 ? 163.427 162.252 193.496 1.00 25.66 ? 166 LYS B N   1 
ATOM   4534 C CA  . LYS B 2 166 ? 162.918 162.412 192.137 1.00 25.66 ? 166 LYS B CA  1 
ATOM   4535 C C   . LYS B 2 166 ? 164.028 162.805 191.172 1.00 25.66 ? 166 LYS B C   1 
ATOM   4536 O O   . LYS B 2 166 ? 164.057 162.340 190.027 1.00 25.66 ? 166 LYS B O   1 
ATOM   4537 C CB  . LYS B 2 166 ? 161.798 163.450 192.114 1.00 25.66 ? 166 LYS B CB  1 
ATOM   4538 C CG  . LYS B 2 166 ? 161.144 163.622 190.757 1.00 25.66 ? 166 LYS B CG  1 
ATOM   4539 C CD  . LYS B 2 166 ? 159.820 164.359 190.875 1.00 25.66 ? 166 LYS B CD  1 
ATOM   4540 C CE  . LYS B 2 166 ? 159.959 165.816 190.466 1.00 25.66 ? 166 LYS B CE  1 
ATOM   4541 N NZ  . LYS B 2 166 ? 158.950 166.679 191.136 1.00 25.66 ? 166 LYS B NZ  1 
ATOM   4542 N N   . ILE B 2 167 ? 164.947 163.663 191.609 1.00 23.18 ? 167 ILE B N   1 
ATOM   4543 C CA  . ILE B 2 167 ? 166.036 164.096 190.739 1.00 23.18 ? 167 ILE B CA  1 
ATOM   4544 C C   . ILE B 2 167 ? 167.103 163.015 190.628 1.00 23.18 ? 167 ILE B C   1 
ATOM   4545 O O   . ILE B 2 167 ? 167.419 162.545 189.530 1.00 23.18 ? 167 ILE B O   1 
ATOM   4546 C CB  . ILE B 2 167 ? 166.636 165.420 191.239 1.00 23.18 ? 167 ILE B CB  1 
ATOM   4547 C CG1 . ILE B 2 167 ? 165.650 166.565 191.015 1.00 23.18 ? 167 ILE B CG1 1 
ATOM   4548 C CG2 . ILE B 2 167 ? 167.948 165.702 190.534 1.00 23.18 ? 167 ILE B CG2 1 
ATOM   4549 C CD1 . ILE B 2 167 ? 165.287 166.775 189.568 1.00 23.18 ? 167 ILE B CD1 1 
ATOM   4550 N N   . LYS B 2 168 ? 167.680 162.612 191.763 1.00 23.47 ? 168 LYS B N   1 
ATOM   4551 C CA  . LYS B 2 168 ? 168.801 161.676 191.723 1.00 23.47 ? 168 LYS B CA  1 
ATOM   4552 C C   . LYS B 2 168 ? 168.377 160.322 191.167 1.00 23.47 ? 168 LYS B C   1 
ATOM   4553 O O   . LYS B 2 168 ? 168.999 159.799 190.236 1.00 23.47 ? 168 LYS B O   1 
ATOM   4554 C CB  . LYS B 2 168 ? 169.400 161.521 193.119 1.00 23.47 ? 168 LYS B CB  1 
ATOM   4555 C CG  . LYS B 2 168 ? 170.328 162.648 193.521 1.00 23.47 ? 168 LYS B CG  1 
ATOM   4556 C CD  . LYS B 2 168 ? 171.385 162.159 194.491 1.00 23.47 ? 168 LYS B CD  1 
ATOM   4557 C CE  . LYS B 2 168 ? 172.237 163.303 195.005 1.00 23.47 ? 168 LYS B CE  1 
ATOM   4558 N NZ  . LYS B 2 168 ? 173.176 162.851 196.062 1.00 23.47 ? 168 LYS B NZ  1 
ATOM   4559 N N   . TYR B 2 169 ? 167.321 159.740 191.724 1.00 28.93 ? 169 TYR B N   1 
ATOM   4560 C CA  . TYR B 2 169 ? 166.847 158.408 191.365 1.00 28.93 ? 169 TYR B CA  1 
ATOM   4561 C C   . TYR B 2 169 ? 165.426 158.513 190.811 1.00 28.93 ? 169 TYR B C   1 
ATOM   4562 O O   . TYR B 2 169 ? 164.946 159.596 190.469 1.00 28.93 ? 169 TYR B O   1 
ATOM   4563 C CB  . TYR B 2 169 ? 166.897 157.454 192.563 1.00 28.93 ? 169 TYR B CB  1 
ATOM   4564 C CG  . TYR B 2 169 ? 168.281 157.070 193.050 1.00 28.93 ? 169 TYR B CG  1 
ATOM   4565 C CD1 . TYR B 2 169 ? 168.440 156.124 194.048 1.00 28.93 ? 169 TYR B CD1 1 
ATOM   4566 C CD2 . TYR B 2 169 ? 169.420 157.654 192.525 1.00 28.93 ? 169 TYR B CD2 1 
ATOM   4567 C CE1 . TYR B 2 169 ? 169.690 155.770 194.502 1.00 28.93 ? 169 TYR B CE1 1 
ATOM   4568 C CE2 . TYR B 2 169 ? 170.673 157.309 192.978 1.00 28.93 ? 169 TYR B CE2 1 
ATOM   4569 C CZ  . TYR B 2 169 ? 170.801 156.367 193.965 1.00 28.93 ? 169 TYR B CZ  1 
ATOM   4570 O OH  . TYR B 2 169 ? 172.049 156.019 194.417 1.00 28.93 ? 169 TYR B OH  1 
ATOM   4571 N N   . SER B 2 170 ? 164.770 157.368 190.676 1.00 37.44 ? 170 SER B N   1 
ATOM   4572 C CA  . SER B 2 170 ? 163.360 157.337 190.329 1.00 37.44 ? 170 SER B CA  1 
ATOM   4573 C C   . SER B 2 170 ? 162.502 157.380 191.590 1.00 37.44 ? 170 SER B C   1 
ATOM   4574 O O   . SER B 2 170 ? 162.930 156.985 192.676 1.00 37.44 ? 170 SER B O   1 
ATOM   4575 C CB  . SER B 2 170 ? 163.032 156.086 189.516 1.00 37.44 ? 170 SER B CB  1 
ATOM   4576 O OG  . SER B 2 170 ? 162.843 154.970 190.367 1.00 37.44 ? 170 SER B OG  1 
ATOM   4577 N N   . GLU B 2 171 ? 161.266 157.860 191.428 1.00 38.48 ? 171 GLU B N   1 
ATOM   4578 C CA  . GLU B 2 171 ? 160.357 158.012 192.560 1.00 38.48 ? 171 GLU B CA  1 
ATOM   4579 C C   . GLU B 2 171 ? 160.019 156.680 193.220 1.00 38.48 ? 171 GLU B C   1 
ATOM   4580 O O   . GLU B 2 171 ? 159.624 156.659 194.395 1.00 38.48 ? 171 GLU B O   1 
ATOM   4581 C CB  . GLU B 2 171 ? 159.080 158.717 192.101 1.00 38.48 ? 171 GLU B CB  1 
ATOM   4582 C CG  . GLU B 2 171 ? 158.200 159.244 193.220 1.00 38.48 ? 171 GLU B CG  1 
ATOM   4583 C CD  . GLU B 2 171 ? 157.123 158.258 193.624 1.00 38.48 ? 171 GLU B CD  1 
ATOM   4584 O OE1 . GLU B 2 171 ? 156.789 157.376 192.808 1.00 38.48 ? 171 GLU B OE1 1 
ATOM   4585 O OE2 . GLU B 2 171 ? 156.602 158.370 194.753 1.00 38.48 ? 171 GLU B OE2 1 
ATOM   4586 N N   . ARG B 2 172 ? 160.164 155.568 192.497 1.00 39.13 ? 172 ARG B N   1 
ATOM   4587 C CA  . ARG B 2 172 ? 159.950 154.263 193.108 1.00 39.13 ? 172 ARG B CA  1 
ATOM   4588 C C   . ARG B 2 172 ? 160.933 154.023 194.247 1.00 39.13 ? 172 ARG B C   1 
ATOM   4589 O O   . ARG B 2 172 ? 160.586 153.377 195.245 1.00 39.13 ? 172 ARG B O   1 
ATOM   4590 C CB  . ARG B 2 172 ? 160.059 153.173 192.043 1.00 39.13 ? 172 ARG B CB  1 
ATOM   4591 C CG  . ARG B 2 172 ? 159.554 151.809 192.471 1.00 39.13 ? 172 ARG B CG  1 
ATOM   4592 C CD  . ARG B 2 172 ? 160.699 150.902 192.870 1.00 39.13 ? 172 ARG B CD  1 
ATOM   4593 N NE  . ARG B 2 172 ? 161.697 150.782 191.810 1.00 39.13 ? 172 ARG B NE  1 
ATOM   4594 C CZ  . ARG B 2 172 ? 161.610 149.935 190.790 1.00 39.13 ? 172 ARG B CZ  1 
ATOM   4595 N NH1 . ARG B 2 172 ? 160.568 149.123 190.686 1.00 39.13 ? 172 ARG B NH1 1 
ATOM   4596 N NH2 . ARG B 2 172 ? 162.567 149.898 189.874 1.00 39.13 ? 172 ARG B NH2 1 
ATOM   4597 N N   . VAL B 2 173 ? 162.153 154.555 194.127 1.00 35.62 ? 173 VAL B N   1 
ATOM   4598 C CA  . VAL B 2 173 ? 163.104 154.499 195.234 1.00 35.62 ? 173 VAL B CA  1 
ATOM   4599 C C   . VAL B 2 173 ? 162.552 155.239 196.442 1.00 35.62 ? 173 VAL B C   1 
ATOM   4600 O O   . VAL B 2 173 ? 162.674 154.776 197.580 1.00 35.62 ? 173 VAL B O   1 
ATOM   4601 C CB  . VAL B 2 173 ? 164.467 155.070 194.805 1.00 35.62 ? 173 VAL B CB  1 
ATOM   4602 C CG1 . VAL B 2 173 ? 165.489 154.870 195.906 1.00 35.62 ? 173 VAL B CG1 1 
ATOM   4603 C CG2 . VAL B 2 173 ? 164.927 154.424 193.517 1.00 35.62 ? 173 VAL B CG2 1 
ATOM   4604 N N   . TYR B 2 174 ? 161.943 156.404 196.214 1.00 29.18 ? 174 TYR B N   1 
ATOM   4605 C CA  . TYR B 2 174 ? 161.343 157.164 197.305 1.00 29.18 ? 174 TYR B CA  1 
ATOM   4606 C C   . TYR B 2 174 ? 160.241 156.365 197.988 1.00 29.18 ? 174 TYR B C   1 
ATOM   4607 O O   . TYR B 2 174 ? 160.163 156.324 199.224 1.00 29.18 ? 174 TYR B O   1 
ATOM   4608 C CB  . TYR B 2 174 ? 160.805 158.489 196.760 1.00 29.18 ? 174 TYR B CB  1 
ATOM   4609 C CG  . TYR B 2 174 ? 159.797 159.207 197.629 1.00 29.18 ? 174 TYR B CG  1 
ATOM   4610 C CD1 . TYR B 2 174 ? 160.193 160.212 198.492 1.00 29.18 ? 174 TYR B CD1 1 
ATOM   4611 C CD2 . TYR B 2 174 ? 158.445 158.907 197.558 1.00 29.18 ? 174 TYR B CD2 1 
ATOM   4612 C CE1 . TYR B 2 174 ? 159.279 160.881 199.272 1.00 29.18 ? 174 TYR B CE1 1 
ATOM   4613 C CE2 . TYR B 2 174 ? 157.527 159.567 198.342 1.00 29.18 ? 174 TYR B CE2 1 
ATOM   4614 C CZ  . TYR B 2 174 ? 157.950 160.553 199.196 1.00 29.18 ? 174 TYR B CZ  1 
ATOM   4615 O OH  . TYR B 2 174 ? 157.037 161.216 199.976 1.00 29.18 ? 174 TYR B OH  1 
ATOM   4616 N N   . ASP B 2 175 ? 159.377 155.726 197.200 1.00 33.53 ? 175 ASP B N   1 
ATOM   4617 C CA  . ASP B 2 175 ? 158.284 154.967 197.800 1.00 33.53 ? 175 ASP B CA  1 
ATOM   4618 C C   . ASP B 2 175 ? 158.807 153.782 198.602 1.00 33.53 ? 175 ASP B C   1 
ATOM   4619 O O   . ASP B 2 175 ? 158.307 153.499 199.699 1.00 33.53 ? 175 ASP B O   1 
ATOM   4620 C CB  . ASP B 2 175 ? 157.307 154.497 196.729 1.00 33.53 ? 175 ASP B CB  1 
ATOM   4621 C CG  . ASP B 2 175 ? 156.087 153.831 197.319 1.00 33.53 ? 175 ASP B CG  1 
ATOM   4622 O OD1 . ASP B 2 175 ? 155.225 154.551 197.865 1.00 33.53 ? 175 ASP B OD1 1 
ATOM   4623 O OD2 . ASP B 2 175 ? 155.993 152.589 197.250 1.00 33.53 ? 175 ASP B OD2 1 
ATOM   4624 N N   . ALA B 2 176 ? 159.810 153.077 198.076 1.00 31.33 ? 176 ALA B N   1 
ATOM   4625 C CA  . ALA B 2 176 ? 160.416 151.994 198.843 1.00 31.33 ? 176 ALA B CA  1 
ATOM   4626 C C   . ALA B 2 176 ? 161.044 152.518 200.126 1.00 31.33 ? 176 ALA B C   1 
ATOM   4627 O O   . ALA B 2 176 ? 160.936 151.888 201.186 1.00 31.33 ? 176 ALA B O   1 
ATOM   4628 C CB  . ALA B 2 176 ? 161.458 151.267 197.998 1.00 31.33 ? 176 ALA B CB  1 
ATOM   4629 N N   . CYS B 2 177 ? 161.699 153.679 200.049 1.00 28.75 ? 177 CYS B N   1 
ATOM   4630 C CA  . CYS B 2 177 ? 162.355 154.244 201.220 1.00 28.75 ? 177 CYS B CA  1 
ATOM   4631 C C   . CYS B 2 177 ? 161.343 154.571 202.305 1.00 28.75 ? 177 CYS B C   1 
ATOM   4632 O O   . CYS B 2 177 ? 161.615 154.375 203.491 1.00 28.75 ? 177 CYS B O   1 
ATOM   4633 C CB  . CYS B 2 177 ? 163.148 155.487 200.826 1.00 28.75 ? 177 CYS B CB  1 
ATOM   4634 S SG  . CYS B 2 177 ? 164.519 155.869 201.921 1.00 28.75 ? 177 CYS B SG  1 
ATOM   4635 N N   . MET B 2 178 ? 160.167 155.069 201.921 1.00 24.21 ? 178 MET B N   1 
ATOM   4636 C CA  . MET B 2 178 ? 159.140 155.333 202.928 1.00 24.21 ? 178 MET B CA  1 
ATOM   4637 C C   . MET B 2 178 ? 158.561 154.041 203.491 1.00 24.21 ? 178 MET B C   1 
ATOM   4638 O O   . MET B 2 178 ? 158.374 153.913 204.712 1.00 24.21 ? 178 MET B O   1 
ATOM   4639 C CB  . MET B 2 178 ? 158.038 156.208 202.343 1.00 24.21 ? 178 MET B CB  1 
ATOM   4640 C CG  . MET B 2 178 ? 158.575 157.513 201.855 1.00 24.21 ? 178 MET B CG  1 
ATOM   4641 S SD  . MET B 2 178 ? 158.970 158.555 203.259 1.00 24.21 ? 178 MET B SD  1 
ATOM   4642 C CE  . MET B 2 178 ? 159.947 159.798 202.445 1.00 24.21 ? 178 MET B CE  1 
ATOM   4643 N N   . ASP B 2 179 ? 158.274 153.069 202.622 1.00 28.52 ? 179 ASP B N   1 
ATOM   4644 C CA  . ASP B 2 179 ? 157.761 151.792 203.099 1.00 28.52 ? 179 ASP B CA  1 
ATOM   4645 C C   . ASP B 2 179 ? 158.749 151.094 204.017 1.00 28.52 ? 179 ASP B C   1 
ATOM   4646 O O   . ASP B 2 179 ? 158.350 150.218 204.789 1.00 28.52 ? 179 ASP B O   1 
ATOM   4647 C CB  . ASP B 2 179 ? 157.417 150.883 201.920 1.00 28.52 ? 179 ASP B CB  1 
ATOM   4648 C CG  . ASP B 2 179 ? 156.016 151.116 201.393 1.00 28.52 ? 179 ASP B CG  1 
ATOM   4649 O OD1 . ASP B 2 179 ? 155.151 151.557 202.176 1.00 28.52 ? 179 ASP B OD1 1 
ATOM   4650 O OD2 . ASP B 2 179 ? 155.778 150.859 200.196 1.00 28.52 ? 179 ASP B OD2 1 
ATOM   4651 N N   . ALA B 2 180 ? 160.028 151.456 203.942 1.00 17.31 ? 180 ALA B N   1 
ATOM   4652 C CA  . ALA B 2 180 ? 161.028 150.868 204.823 1.00 17.31 ? 180 ALA B CA  1 
ATOM   4653 C C   . ALA B 2 180 ? 161.319 151.711 206.062 1.00 17.31 ? 180 ALA B C   1 
ATOM   4654 O O   . ALA B 2 180 ? 161.687 151.152 207.099 1.00 17.31 ? 180 ALA B O   1 
ATOM   4655 C CB  . ALA B 2 180 ? 162.315 150.618 204.043 1.00 17.31 ? 180 ALA B CB  1 
ATOM   4656 N N   . PHE B 2 181 ? 161.179 153.040 205.985 1.00 16.12 ? 181 PHE B N   1 
ATOM   4657 C CA  . PHE B 2 181 ? 161.164 153.852 207.201 1.00 16.12 ? 181 PHE B CA  1 
ATOM   4658 C C   . PHE B 2 181 ? 159.991 153.589 208.126 1.00 16.12 ? 181 PHE B C   1 
ATOM   4659 O O   . PHE B 2 181 ? 160.026 153.961 209.303 1.00 16.12 ? 181 PHE B O   1 
ATOM   4660 C CB  . PHE B 2 181 ? 161.024 155.341 206.884 1.00 16.12 ? 181 PHE B CB  1 
ATOM   4661 C CG  . PHE B 2 181 ? 162.253 155.978 206.324 1.00 16.12 ? 181 PHE B CG  1 
ATOM   4662 C CD1 . PHE B 2 181 ? 163.474 155.354 206.405 1.00 16.12 ? 181 PHE B CD1 1 
ATOM   4663 C CD2 . PHE B 2 181 ? 162.190 157.237 205.764 1.00 16.12 ? 181 PHE B CD2 1 
ATOM   4664 C CE1 . PHE B 2 181 ? 164.603 155.960 205.911 1.00 16.12 ? 181 PHE B CE1 1 
ATOM   4665 C CE2 . PHE B 2 181 ? 163.314 157.843 205.270 1.00 16.12 ? 181 PHE B CE2 1 
ATOM   4666 C CZ  . PHE B 2 181 ? 164.521 157.204 205.343 1.00 16.12 ? 181 PHE B CZ  1 
ATOM   4667 N N   . ASP B 2 182 ? 158.942 152.948 207.615 1.00 19.27 ? 182 ASP B N   1 
ATOM   4668 C CA  . ASP B 2 182 ? 157.702 152.857 208.380 1.00 19.27 ? 182 ASP B CA  1 
ATOM   4669 C C   . ASP B 2 182 ? 157.811 151.671 209.336 1.00 19.27 ? 182 ASP B C   1 
ATOM   4670 O O   . ASP B 2 182 ? 156.810 151.318 209.966 1.00 19.27 ? 182 ASP B O   1 
ATOM   4671 C CB  . ASP B 2 182 ? 156.474 152.686 207.485 1.00 19.27 ? 182 ASP B CB  1 
ATOM   4672 C CG  . ASP B 2 182 ? 155.831 154.009 207.122 1.00 19.27 ? 182 ASP B CG  1 
ATOM   4673 O OD1 . ASP B 2 182 ? 156.377 155.063 207.504 1.00 19.27 ? 182 ASP B OD1 1 
ATOM   4674 O OD2 . ASP B 2 182 ? 154.780 153.996 206.450 1.00 19.27 ? 182 ASP B OD2 1 
ATOM   4675 N N   . CYS B 2 183 ? 158.980 151.039 209.463 1.00 15.88 ? 183 CYS B N   1 
ATOM   4676 C CA  . CYS B 2 183 ? 159.105 149.838 210.280 1.00 15.88 ? 183 CYS B CA  1 
ATOM   4677 C C   . CYS B 2 183 ? 160.195 149.932 211.347 1.00 15.88 ? 183 CYS B C   1 
ATOM   4678 O O   . CYS B 2 183 ? 160.514 148.924 211.983 1.00 15.88 ? 183 CYS B O   1 
ATOM   4679 C CB  . CYS B 2 183 ? 159.351 148.625 209.386 1.00 15.88 ? 183 CYS B CB  1 
ATOM   4680 S SG  . CYS B 2 183 ? 160.998 148.554 208.674 1.00 15.88 ? 183 CYS B SG  1 
ATOM   4681 N N   . LEU B 2 184 ? 160.761 151.110 211.573 1.00 11.69 ? 184 LEU B N   1 
ATOM   4682 C CA  . LEU B 2 184 ? 161.828 151.258 212.552 1.00 11.69 ? 184 LEU B CA  1 
ATOM   4683 C C   . LEU B 2 184 ? 161.288 151.107 213.971 1.00 11.69 ? 184 LEU B C   1 
ATOM   4684 O O   . LEU B 2 184 ? 160.097 151.302 214.213 1.00 11.69 ? 184 LEU B O   1 
ATOM   4685 C CB  . LEU B 2 184 ? 162.500 152.618 212.387 1.00 11.69 ? 184 LEU B CB  1 
ATOM   4686 C CG  . LEU B 2 184 ? 163.395 152.796 211.161 1.00 11.69 ? 184 LEU B CG  1 
ATOM   4687 C CD1 . LEU B 2 184 ? 163.440 154.233 210.726 1.00 11.69 ? 184 LEU B CD1 1 
ATOM   4688 C CD2 . LEU B 2 184 ? 164.780 152.314 211.468 1.00 11.69 ? 184 LEU B CD2 1 
ATOM   4689 N N   . PRO B 2 185 ? 162.135 150.733 214.925 1.00 10.78 ? 185 PRO B N   1 
ATOM   4690 C CA  . PRO B 2 185 ? 161.720 150.732 216.330 1.00 10.78 ? 185 PRO B CA  1 
ATOM   4691 C C   . PRO B 2 185 ? 161.704 152.150 216.875 1.00 10.78 ? 185 PRO B C   1 
ATOM   4692 O O   . PRO B 2 185 ? 162.137 153.095 216.220 1.00 10.78 ? 185 PRO B O   1 
ATOM   4693 C CB  . PRO B 2 185 ? 162.784 149.880 217.022 1.00 10.78 ? 185 PRO B CB  1 
ATOM   4694 C CG  . PRO B 2 185 ? 163.965 149.992 216.164 1.00 10.78 ? 185 PRO B CG  1 
ATOM   4695 C CD  . PRO B 2 185 ? 163.489 150.186 214.756 1.00 10.78 ? 185 PRO B CD  1 
ATOM   4696 N N   . LEU B 2 186 ? 161.176 152.297 218.091 1.00 11.78 ? 186 LEU B N   1 
ATOM   4697 C CA  . LEU B 2 186 ? 160.967 153.638 218.615 1.00 11.78 ? 186 LEU B CA  1 
ATOM   4698 C C   . LEU B 2 186 ? 161.273 153.845 220.092 1.00 11.78 ? 186 LEU B C   1 
ATOM   4699 O O   . LEU B 2 186 ? 161.082 154.964 220.574 1.00 11.78 ? 186 LEU B O   1 
ATOM   4700 C CB  . LEU B 2 186 ? 159.521 154.080 218.334 1.00 11.78 ? 186 LEU B CB  1 
ATOM   4701 C CG  . LEU B 2 186 ? 158.363 153.201 218.810 1.00 11.78 ? 186 LEU B CG  1 
ATOM   4702 C CD1 . LEU B 2 186 ? 157.949 153.520 220.230 1.00 11.78 ? 186 LEU B CD1 1 
ATOM   4703 C CD2 . LEU B 2 186 ? 157.187 153.355 217.875 1.00 11.78 ? 186 LEU B CD2 1 
ATOM   4704 N N   . ALA B 2 187 ? 161.736 152.839 220.831 1.00 10.47 ? 187 ALA B N   1 
ATOM   4705 C CA  . ALA B 2 187 ? 161.973 153.032 222.259 1.00 10.47 ? 187 ALA B CA  1 
ATOM   4706 C C   . ALA B 2 187 ? 163.430 152.848 222.659 1.00 10.47 ? 187 ALA B C   1 
ATOM   4707 O O   . ALA B 2 187 ? 164.028 153.774 223.209 1.00 10.47 ? 187 ALA B O   1 
ATOM   4708 C CB  . ALA B 2 187 ? 161.080 152.086 223.062 1.00 10.47 ? 187 ALA B CB  1 
ATOM   4709 N N   . ALA B 2 188 ? 164.015 151.676 222.418 1.00 12.16 ? 188 ALA B N   1 
ATOM   4710 C CA  . ALA B 2 188 ? 165.440 151.425 222.630 1.00 12.16 ? 188 ALA B CA  1 
ATOM   4711 C C   . ALA B 2 188 ? 165.864 151.690 224.080 1.00 12.16 ? 188 ALA B C   1 
ATOM   4712 O O   . ALA B 2 188 ? 166.598 152.628 224.386 1.00 12.16 ? 188 ALA B O   1 
ATOM   4713 C CB  . ALA B 2 188 ? 166.280 152.253 221.654 1.00 12.16 ? 188 ALA B CB  1 
ATOM   4714 N N   . LEU B 2 189 ? 165.369 150.838 224.971 1.00 11.40 ? 189 LEU B N   1 
ATOM   4715 C CA  . LEU B 2 189 ? 165.908 150.796 226.323 1.00 11.40 ? 189 LEU B CA  1 
ATOM   4716 C C   . LEU B 2 189 ? 167.397 150.481 226.270 1.00 11.40 ? 189 LEU B C   1 
ATOM   4717 O O   . LEU B 2 189 ? 167.864 149.758 225.390 1.00 11.40 ? 189 LEU B O   1 
ATOM   4718 C CB  . LEU B 2 189 ? 165.175 149.748 227.154 1.00 11.40 ? 189 LEU B CB  1 
ATOM   4719 C CG  . LEU B 2 189 ? 165.530 149.600 228.629 1.00 11.40 ? 189 LEU B CG  1 
ATOM   4720 C CD1 . LEU B 2 189 ? 164.299 149.267 229.420 1.00 11.40 ? 189 LEU B CD1 1 
ATOM   4721 C CD2 . LEU B 2 189 ? 166.552 148.505 228.802 1.00 11.40 ? 189 LEU B CD2 1 
ATOM   4722 N N   . MET B 2 190 ? 168.154 151.035 227.216 1.00 19.37 ? 190 MET B N   1 
ATOM   4723 C CA  . MET B 2 190 ? 169.612 150.935 227.197 1.00 19.37 ? 190 MET B CA  1 
ATOM   4724 C C   . MET B 2 190 ? 170.138 150.543 228.571 1.00 19.37 ? 190 MET B C   1 
ATOM   4725 O O   . MET B 2 190 ? 170.046 151.328 229.519 1.00 19.37 ? 190 MET B O   1 
ATOM   4726 C CB  . MET B 2 190 ? 170.237 152.252 226.744 1.00 19.37 ? 190 MET B CB  1 
ATOM   4727 C CG  . MET B 2 190 ? 171.711 152.155 226.430 1.00 19.37 ? 190 MET B CG  1 
ATOM   4728 S SD  . MET B 2 190 ? 172.744 152.627 227.820 1.00 19.37 ? 190 MET B SD  1 
ATOM   4729 C CE  . MET B 2 190 ? 173.248 154.264 227.302 1.00 19.37 ? 190 MET B CE  1 
ATOM   4730 N N   . ASN B 2 191 ? 170.701 149.338 228.670 1.00 24.50 ? 191 ASN B N   1 
ATOM   4731 C CA  . ASN B 2 191 ? 171.424 148.879 229.859 1.00 24.50 ? 191 ASN B CA  1 
ATOM   4732 C C   . ASN B 2 191 ? 170.529 148.795 231.092 1.00 24.50 ? 191 ASN B C   1 
ATOM   4733 O O   . ASN B 2 191 ? 171.012 148.872 232.224 1.00 24.50 ? 191 ASN B O   1 
ATOM   4734 C CB  . ASN B 2 191 ? 172.636 149.769 230.147 1.00 24.50 ? 191 ASN B CB  1 
ATOM   4735 C CG  . ASN B 2 191 ? 173.656 149.092 231.036 1.00 24.50 ? 191 ASN B CG  1 
ATOM   4736 O OD1 . ASN B 2 191 ? 173.530 147.911 231.355 1.00 24.50 ? 191 ASN B OD1 1 
ATOM   4737 N ND2 . ASN B 2 191 ? 174.669 149.839 231.448 1.00 24.50 ? 191 ASN B ND2 1 
ATOM   4738 N N   . GLN B 2 192 ? 169.222 148.637 230.889 1.00 27.06 ? 192 GLN B N   1 
ATOM   4739 C CA  . GLN B 2 192 ? 168.245 148.520 231.972 1.00 27.06 ? 192 GLN B CA  1 
ATOM   4740 C C   . GLN B 2 192 ? 168.298 149.699 232.938 1.00 27.06 ? 192 GLN B C   1 
ATOM   4741 O O   . GLN B 2 192 ? 167.810 149.601 234.066 1.00 27.06 ? 192 GLN B O   1 
ATOM   4742 C CB  . GLN B 2 192 ? 168.420 147.203 232.738 1.00 27.06 ? 192 GLN B CB  1 
ATOM   4743 N N   . GLN B 2 193 ? 168.884 150.817 232.518 1.00 25.83 ? 193 GLN B N   1 
ATOM   4744 C CA  . GLN B 2 193 ? 168.986 151.987 233.376 1.00 25.83 ? 193 GLN B CA  1 
ATOM   4745 C C   . GLN B 2 193 ? 168.465 153.231 232.675 1.00 25.83 ? 193 GLN B C   1 
ATOM   4746 O O   . GLN B 2 193 ? 167.946 154.140 233.327 1.00 25.83 ? 193 GLN B O   1 
ATOM   4747 C CB  . GLN B 2 193 ? 170.432 152.214 233.810 1.00 25.83 ? 193 GLN B CB  1 
ATOM   4748 C CG  . GLN B 2 193 ? 171.008 151.131 234.696 1.00 25.83 ? 193 GLN B CG  1 
ATOM   4749 C CD  . GLN B 2 193 ? 172.273 151.581 235.402 1.00 25.83 ? 193 GLN B CD  1 
ATOM   4750 O OE1 . GLN B 2 193 ? 172.549 152.776 235.503 1.00 25.83 ? 193 GLN B OE1 1 
ATOM   4751 N NE2 . GLN B 2 193 ? 173.052 150.624 235.889 1.00 25.83 ? 193 GLN B NE2 1 
ATOM   4752 N N   . PHE B 2 194 ? 168.610 153.294 231.357 1.00 18.85 ? 194 PHE B N   1 
ATOM   4753 C CA  . PHE B 2 194 ? 168.263 154.481 230.593 1.00 18.85 ? 194 PHE B CA  1 
ATOM   4754 C C   . PHE B 2 194 ? 167.060 154.202 229.704 1.00 18.85 ? 194 PHE B C   1 
ATOM   4755 O O   . PHE B 2 194 ? 166.617 153.064 229.549 1.00 18.85 ? 194 PHE B O   1 
ATOM   4756 C CB  . PHE B 2 194 ? 169.436 154.953 229.723 1.00 18.85 ? 194 PHE B CB  1 
ATOM   4757 C CG  . PHE B 2 194 ? 170.626 155.468 230.492 1.00 18.85 ? 194 PHE B CG  1 
ATOM   4758 C CD1 . PHE B 2 194 ? 170.751 155.276 231.853 1.00 18.85 ? 194 PHE B CD1 1 
ATOM   4759 C CD2 . PHE B 2 194 ? 171.620 156.168 229.835 1.00 18.85 ? 194 PHE B CD2 1 
ATOM   4760 C CE1 . PHE B 2 194 ? 171.846 155.751 232.537 1.00 18.85 ? 194 PHE B CE1 1 
ATOM   4761 C CE2 . PHE B 2 194 ? 172.712 156.649 230.516 1.00 18.85 ? 194 PHE B CE2 1 
ATOM   4762 C CZ  . PHE B 2 194 ? 172.825 156.441 231.869 1.00 18.85 ? 194 PHE B CZ  1 
ATOM   4763 N N   . LEU B 2 195 ? 166.532 155.271 229.120 1.00 12.04 ? 195 LEU B N   1 
ATOM   4764 C CA  . LEU B 2 195 ? 165.560 155.189 228.041 1.00 12.04 ? 195 LEU B CA  1 
ATOM   4765 C C   . LEU B 2 195 ? 165.995 156.161 226.957 1.00 12.04 ? 195 LEU B C   1 
ATOM   4766 O O   . LEU B 2 195 ? 166.413 157.281 227.256 1.00 12.04 ? 195 LEU B O   1 
ATOM   4767 C CB  . LEU B 2 195 ? 164.149 155.520 228.518 1.00 12.04 ? 195 LEU B CB  1 
ATOM   4768 C CG  . LEU B 2 195 ? 163.039 155.261 227.503 1.00 12.04 ? 195 LEU B CG  1 
ATOM   4769 C CD1 . LEU B 2 195 ? 162.667 153.803 227.499 1.00 12.04 ? 195 LEU B CD1 1 
ATOM   4770 C CD2 . LEU B 2 195 ? 161.825 156.108 227.798 1.00 12.04 ? 195 LEU B CD2 1 
ATOM   4771 N N   . CYS B 2 196 ? 165.910 155.734 225.698 1.00 13.08 ? 196 CYS B N   1 
ATOM   4772 C CA  . CYS B 2 196 ? 166.482 156.491 224.585 1.00 13.08 ? 196 CYS B CA  1 
ATOM   4773 C C   . CYS B 2 196 ? 165.422 156.717 223.511 1.00 13.08 ? 196 CYS B C   1 
ATOM   4774 O O   . CYS B 2 196 ? 165.359 155.966 222.538 1.00 13.08 ? 196 CYS B O   1 
ATOM   4775 C CB  . CYS B 2 196 ? 167.686 155.757 224.027 1.00 13.08 ? 196 CYS B CB  1 
ATOM   4776 S SG  . CYS B 2 196 ? 168.990 155.468 225.230 1.00 13.08 ? 196 CYS B SG  1 
ATOM   4777 N N   . VAL B 2 197 ? 164.624 157.770 223.663 1.00 10.34 ? 197 VAL B N   1 
ATOM   4778 C CA  . VAL B 2 197 ? 163.581 158.102 222.703 1.00 10.34 ? 197 VAL B CA  1 
ATOM   4779 C C   . VAL B 2 197 ? 163.993 159.350 221.938 1.00 10.34 ? 197 VAL B C   1 
ATOM   4780 O O   . VAL B 2 197 ? 164.832 160.134 222.381 1.00 10.34 ? 197 VAL B O   1 
ATOM   4781 C CB  . VAL B 2 197 ? 162.213 158.303 223.381 1.00 10.34 ? 197 VAL B CB  1 
ATOM   4782 C CG1 . VAL B 2 197 ? 161.682 156.993 223.901 1.00 10.34 ? 197 VAL B CG1 1 
ATOM   4783 C CG2 . VAL B 2 197 ? 162.338 159.291 224.513 1.00 10.34 ? 197 VAL B CG2 1 
ATOM   4784 N N   . HIS B 2 198 ? 163.392 159.531 220.762 1.00 6.80  ? 198 HIS B N   1 
ATOM   4785 C CA  . HIS B 2 198 ? 163.756 160.674 219.931 1.00 6.80  ? 198 HIS B CA  1 
ATOM   4786 C C   . HIS B 2 198 ? 163.152 161.973 220.445 1.00 6.80  ? 198 HIS B C   1 
ATOM   4787 O O   . HIS B 2 198 ? 163.792 163.024 220.376 1.00 6.80  ? 198 HIS B O   1 
ATOM   4788 C CB  . HIS B 2 198 ? 163.325 160.444 218.491 1.00 6.80  ? 198 HIS B CB  1 
ATOM   4789 C CG  . HIS B 2 198 ? 163.456 161.658 217.630 1.00 6.80  ? 198 HIS B CG  1 
ATOM   4790 N ND1 . HIS B 2 198 ? 164.665 162.273 217.398 1.00 6.80  ? 198 HIS B ND1 1 
ATOM   4791 C CD2 . HIS B 2 198 ? 162.536 162.363 216.935 1.00 6.80  ? 198 HIS B CD2 1 
ATOM   4792 C CE1 . HIS B 2 198 ? 164.483 163.309 216.600 1.00 6.80  ? 198 HIS B CE1 1 
ATOM   4793 N NE2 . HIS B 2 198 ? 163.201 163.383 216.300 1.00 6.80  ? 198 HIS B NE2 1 
ATOM   4794 N N   . GLY B 2 199 ? 161.921 161.928 220.932 1.00 11.32 ? 199 GLY B N   1 
ATOM   4795 C CA  . GLY B 2 199 ? 161.262 163.095 221.479 1.00 11.32 ? 199 GLY B CA  1 
ATOM   4796 C C   . GLY B 2 199 ? 161.236 163.070 222.989 1.00 11.32 ? 199 GLY B C   1 
ATOM   4797 O O   . GLY B 2 199 ? 162.198 163.478 223.640 1.00 11.32 ? 199 GLY B O   1 
ATOM   4798 N N   . GLY B 2 200 ? 160.130 162.616 223.554 1.00 14.52 ? 200 GLY B N   1 
ATOM   4799 C CA  . GLY B 2 200 ? 160.027 162.519 224.991 1.00 14.52 ? 200 GLY B CA  1 
ATOM   4800 C C   . GLY B 2 200 ? 158.809 161.726 225.401 1.00 14.52 ? 200 GLY B C   1 
ATOM   4801 O O   . GLY B 2 200 ? 158.211 161.016 224.593 1.00 14.52 ? 200 GLY B O   1 
ATOM   4802 N N   . LEU B 2 201 ? 158.437 161.872 226.670 1.00 19.38 ? 201 LEU B N   1 
ATOM   4803 C CA  . LEU B 2 201 ? 157.339 161.107 227.240 1.00 19.38 ? 201 LEU B CA  1 
ATOM   4804 C C   . LEU B 2 201 ? 156.011 161.542 226.629 1.00 19.38 ? 201 LEU B C   1 
ATOM   4805 O O   . LEU B 2 201 ? 155.945 162.402 225.747 1.00 19.38 ? 201 LEU B O   1 
ATOM   4806 C CB  . LEU B 2 201 ? 157.300 161.280 228.754 1.00 19.38 ? 201 LEU B CB  1 
ATOM   4807 C CG  . LEU B 2 201 ? 158.636 161.333 229.489 1.00 19.38 ? 201 LEU B CG  1 
ATOM   4808 C CD1 . LEU B 2 201 ? 158.415 161.678 230.948 1.00 19.38 ? 201 LEU B CD1 1 
ATOM   4809 C CD2 . LEU B 2 201 ? 159.364 160.013 229.360 1.00 19.38 ? 201 LEU B CD2 1 
ATOM   4810 N N   . SER B 2 202 ? 154.930 160.926 227.109 1.00 28.41 ? 202 SER B N   1 
ATOM   4811 C CA  . SER B 2 202 ? 153.586 161.299 226.712 1.00 28.41 ? 202 SER B CA  1 
ATOM   4812 C C   . SER B 2 202 ? 152.633 160.973 227.851 1.00 28.41 ? 202 SER B C   1 
ATOM   4813 O O   . SER B 2 202 ? 152.838 159.969 228.547 1.00 28.41 ? 202 SER B O   1 
ATOM   4814 C CB  . SER B 2 202 ? 153.143 160.577 225.441 1.00 28.41 ? 202 SER B CB  1 
ATOM   4815 O OG  . SER B 2 202 ? 151.820 160.940 225.099 1.00 28.41 ? 202 SER B OG  1 
ATOM   4816 N N   . PRO B 2 203 ? 151.604 161.793 228.073 1.00 33.83 ? 203 PRO B N   1 
ATOM   4817 C CA  . PRO B 2 203 ? 150.654 161.497 229.158 1.00 33.83 ? 203 PRO B CA  1 
ATOM   4818 C C   . PRO B 2 203 ? 149.955 160.160 229.008 1.00 33.83 ? 203 PRO B C   1 
ATOM   4819 O O   . PRO B 2 203 ? 149.598 159.545 230.020 1.00 33.83 ? 203 PRO B O   1 
ATOM   4820 C CB  . PRO B 2 203 ? 149.663 162.663 229.076 1.00 33.83 ? 203 PRO B CB  1 
ATOM   4821 C CG  . PRO B 2 203 ? 150.451 163.771 228.472 1.00 33.83 ? 203 PRO B CG  1 
ATOM   4822 C CD  . PRO B 2 203 ? 151.365 163.117 227.478 1.00 33.83 ? 203 PRO B CD  1 
ATOM   4823 N N   . GLU B 2 204 ? 149.738 159.692 227.780 1.00 35.74 ? 204 GLU B N   1 
ATOM   4824 C CA  . GLU B 2 204 ? 149.101 158.398 227.574 1.00 35.74 ? 204 GLU B CA  1 
ATOM   4825 C C   . GLU B 2 204 ? 150.052 157.230 227.801 1.00 35.74 ? 204 GLU B C   1 
ATOM   4826 O O   . GLU B 2 204 ? 149.600 156.080 227.806 1.00 35.74 ? 204 GLU B O   1 
ATOM   4827 C CB  . GLU B 2 204 ? 148.516 158.324 226.162 1.00 35.74 ? 204 GLU B CB  1 
ATOM   4828 C CG  . GLU B 2 204 ? 147.268 159.172 225.961 1.00 35.74 ? 204 GLU B CG  1 
ATOM   4829 C CD  . GLU B 2 204 ? 146.449 158.739 224.758 1.00 35.74 ? 204 GLU B CD  1 
ATOM   4830 O OE1 . GLU B 2 204 ? 145.676 159.567 224.233 1.00 35.74 ? 204 GLU B OE1 1 
ATOM   4831 O OE2 . GLU B 2 204 ? 146.576 157.570 224.339 1.00 35.74 ? 204 GLU B OE2 1 
ATOM   4832 N N   . ILE B 2 205 ? 151.345 157.493 227.982 1.00 38.74 ? 205 ILE B N   1 
ATOM   4833 C CA  . ILE B 2 205 ? 152.354 156.465 228.219 1.00 38.74 ? 205 ILE B CA  1 
ATOM   4834 C C   . ILE B 2 205 ? 152.909 156.671 229.621 1.00 38.74 ? 205 ILE B C   1 
ATOM   4835 O O   . ILE B 2 205 ? 153.534 157.700 229.904 1.00 38.74 ? 205 ILE B O   1 
ATOM   4836 C CB  . ILE B 2 205 ? 153.475 156.525 227.171 1.00 38.74 ? 205 ILE B CB  1 
ATOM   4837 C CG1 . ILE B 2 205 ? 153.000 155.938 225.843 1.00 38.74 ? 205 ILE B CG1 1 
ATOM   4838 C CG2 . ILE B 2 205 ? 154.707 155.796 227.665 1.00 38.74 ? 205 ILE B CG2 1 
ATOM   4839 C CD1 . ILE B 2 205 ? 153.667 156.559 224.643 1.00 38.74 ? 205 ILE B CD1 1 
ATOM   4840 N N   . ASN B 2 206 ? 152.694 155.697 230.495 1.00 43.46 ? 206 ASN B N   1 
ATOM   4841 C CA  . ASN B 2 206 ? 153.106 155.835 231.886 1.00 43.46 ? 206 ASN B CA  1 
ATOM   4842 C C   . ASN B 2 206 ? 154.097 154.774 232.327 1.00 43.46 ? 206 ASN B C   1 
ATOM   4843 O O   . ASN B 2 206 ? 155.007 155.074 233.102 1.00 43.46 ? 206 ASN B O   1 
ATOM   4844 C CB  . ASN B 2 206 ? 151.878 155.797 232.803 1.00 43.46 ? 206 ASN B CB  1 
ATOM   4845 C CG  . ASN B 2 206 ? 152.025 156.707 234.004 1.00 43.46 ? 206 ASN B CG  1 
ATOM   4846 O OD1 . ASN B 2 206 ? 153.057 157.352 234.184 1.00 43.46 ? 206 ASN B OD1 1 
ATOM   4847 N ND2 . ASN B 2 206 ? 150.989 156.767 234.832 1.00 43.46 ? 206 ASN B ND2 1 
ATOM   4848 N N   . THR B 2 207 ? 153.946 153.543 231.856 1.00 44.94 ? 207 THR B N   1 
ATOM   4849 C CA  . THR B 2 207 ? 154.862 152.459 232.164 1.00 44.94 ? 207 THR B CA  1 
ATOM   4850 C C   . THR B 2 207 ? 155.495 151.985 230.863 1.00 44.94 ? 207 THR B C   1 
ATOM   4851 O O   . THR B 2 207 ? 154.905 152.122 229.789 1.00 44.94 ? 207 THR B O   1 
ATOM   4852 C CB  . THR B 2 207 ? 154.130 151.307 232.876 1.00 44.94 ? 207 THR B CB  1 
ATOM   4853 O OG1 . THR B 2 207 ? 153.559 151.794 234.096 1.00 44.94 ? 207 THR B OG1 1 
ATOM   4854 C CG2 . THR B 2 207 ? 155.076 150.160 233.206 1.00 44.94 ? 207 THR B CG2 1 
ATOM   4855 N N   . LEU B 2 208 ? 156.713 151.449 230.962 1.00 34.48 ? 208 LEU B N   1 
ATOM   4856 C CA  . LEU B 2 208 ? 157.439 151.033 229.767 1.00 34.48 ? 208 LEU B CA  1 
ATOM   4857 C C   . LEU B 2 208 ? 156.628 150.045 228.940 1.00 34.48 ? 208 LEU B C   1 
ATOM   4858 O O   . LEU B 2 208 ? 156.626 150.113 227.706 1.00 34.48 ? 208 LEU B O   1 
ATOM   4859 C CB  . LEU B 2 208 ? 158.786 150.434 230.160 1.00 34.48 ? 208 LEU B CB  1 
ATOM   4860 C CG  . LEU B 2 208 ? 159.935 151.434 230.277 1.00 34.48 ? 208 LEU B CG  1 
ATOM   4861 C CD1 . LEU B 2 208 ? 159.794 152.313 231.504 1.00 34.48 ? 208 LEU B CD1 1 
ATOM   4862 C CD2 . LEU B 2 208 ? 161.238 150.692 230.323 1.00 34.48 ? 208 LEU B CD2 1 
ATOM   4863 N N   . ASP B 2 209 ? 155.901 149.142 229.600 1.00 38.82 ? 209 ASP B N   1 
ATOM   4864 C CA  . ASP B 2 209 ? 155.087 148.178 228.870 1.00 38.82 ? 209 ASP B CA  1 
ATOM   4865 C C   . ASP B 2 209 ? 154.081 148.856 227.950 1.00 38.82 ? 209 ASP B C   1 
ATOM   4866 O O   . ASP B 2 209 ? 153.669 148.255 226.952 1.00 38.82 ? 209 ASP B O   1 
ATOM   4867 C CB  . ASP B 2 209 ? 154.359 147.255 229.848 1.00 38.82 ? 209 ASP B CB  1 
ATOM   4868 N N   . ASP B 2 210 ? 153.689 150.096 228.252 1.00 34.44 ? 210 ASP B N   1 
ATOM   4869 C CA  . ASP B 2 210 ? 152.730 150.802 227.412 1.00 34.44 ? 210 ASP B CA  1 
ATOM   4870 C C   . ASP B 2 210 ? 153.273 151.107 226.022 1.00 34.44 ? 210 ASP B C   1 
ATOM   4871 O O   . ASP B 2 210 ? 152.476 151.350 225.111 1.00 34.44 ? 210 ASP B O   1 
ATOM   4872 C CB  . ASP B 2 210 ? 152.284 152.097 228.089 1.00 34.44 ? 210 ASP B CB  1 
ATOM   4873 N N   . ILE B 2 211 ? 154.594 151.110 225.827 1.00 28.98 ? 211 ILE B N   1 
ATOM   4874 C CA  . ILE B 2 211 ? 155.148 151.251 224.482 1.00 28.98 ? 211 ILE B CA  1 
ATOM   4875 C C   . ILE B 2 211 ? 155.576 149.911 223.902 1.00 28.98 ? 211 ILE B C   1 
ATOM   4876 O O   . ILE B 2 211 ? 156.191 149.873 222.835 1.00 28.98 ? 211 ILE B O   1 
ATOM   4877 C CB  . ILE B 2 211 ? 156.306 152.263 224.427 1.00 28.98 ? 211 ILE B CB  1 
ATOM   4878 C CG1 . ILE B 2 211 ? 157.358 151.973 225.485 1.00 28.98 ? 211 ILE B CG1 1 
ATOM   4879 C CG2 . ILE B 2 211 ? 155.795 153.669 224.582 1.00 28.98 ? 211 ILE B CG2 1 
ATOM   4880 C CD1 . ILE B 2 211 ? 158.542 152.885 225.395 1.00 28.98 ? 211 ILE B CD1 1 
ATOM   4881 N N   . ARG B 2 212 ? 155.256 148.810 224.573 1.00 33.37 ? 212 ARG B N   1 
ATOM   4882 C CA  . ARG B 2 212 ? 155.477 147.481 224.025 1.00 33.37 ? 212 ARG B CA  1 
ATOM   4883 C C   . ARG B 2 212 ? 154.262 146.946 223.279 1.00 33.37 ? 212 ARG B C   1 
ATOM   4884 O O   . ARG B 2 212 ? 154.309 145.818 222.778 1.00 33.37 ? 212 ARG B O   1 
ATOM   4885 C CB  . ARG B 2 212 ? 155.861 146.507 225.142 1.00 33.37 ? 212 ARG B CB  1 
ATOM   4886 C CG  . ARG B 2 212 ? 157.250 146.718 225.705 1.00 33.37 ? 212 ARG B CG  1 
ATOM   4887 C CD  . ARG B 2 212 ? 158.021 145.414 225.791 1.00 33.37 ? 212 ARG B CD  1 
ATOM   4888 N NE  . ARG B 2 212 ? 159.300 145.583 226.475 1.00 33.37 ? 212 ARG B NE  1 
ATOM   4889 C CZ  . ARG B 2 212 ? 159.478 145.427 227.783 1.00 33.37 ? 212 ARG B CZ  1 
ATOM   4890 N NH1 . ARG B 2 212 ? 158.457 145.091 228.558 1.00 33.37 ? 212 ARG B NH1 1 
ATOM   4891 N NH2 . ARG B 2 212 ? 160.677 145.604 228.318 1.00 33.37 ? 212 ARG B NH2 1 
ATOM   4892 N N   . LYS B 2 213 ? 153.182 147.721 223.188 1.00 37.12 ? 213 LYS B N   1 
ATOM   4893 C CA  . LYS B 2 213 ? 151.918 147.246 222.640 1.00 37.12 ? 213 LYS B CA  1 
ATOM   4894 C C   . LYS B 2 213 ? 151.575 147.853 221.289 1.00 37.12 ? 213 LYS B C   1 
ATOM   4895 O O   . LYS B 2 213 ? 151.228 147.121 220.358 1.00 37.12 ? 213 LYS B O   1 
ATOM   4896 C CB  . LYS B 2 213 ? 150.778 147.532 223.626 1.00 37.12 ? 213 LYS B CB  1 
ATOM   4897 C CG  . LYS B 2 213 ? 151.109 147.215 225.069 1.00 37.12 ? 213 LYS B CG  1 
ATOM   4898 C CD  . LYS B 2 213 ? 149.990 147.662 225.991 1.00 37.12 ? 213 LYS B CD  1 
ATOM   4899 C CE  . LYS B 2 213 ? 148.632 147.215 225.473 1.00 37.12 ? 213 LYS B CE  1 
ATOM   4900 N NZ  . LYS B 2 213 ? 148.528 145.735 225.376 1.00 37.12 ? 213 LYS B NZ  1 
ATOM   4901 N N   . LEU B 2 214 ? 151.647 149.174 221.157 1.00 37.43 ? 214 LEU B N   1 
ATOM   4902 C CA  . LEU B 2 214 ? 151.191 149.823 219.936 1.00 37.43 ? 214 LEU B CA  1 
ATOM   4903 C C   . LEU B 2 214 ? 152.075 149.438 218.757 1.00 37.43 ? 214 LEU B C   1 
ATOM   4904 O O   . LEU B 2 214 ? 153.288 149.263 218.898 1.00 37.43 ? 214 LEU B O   1 
ATOM   4905 C CB  . LEU B 2 214 ? 151.170 151.345 220.105 1.00 37.43 ? 214 LEU B CB  1 
ATOM   4906 C CG  . LEU B 2 214 ? 152.476 152.140 220.137 1.00 37.43 ? 214 LEU B CG  1 
ATOM   4907 C CD1 . LEU B 2 214 ? 152.180 153.609 219.922 1.00 37.43 ? 214 LEU B CD1 1 
ATOM   4908 C CD2 . LEU B 2 214 ? 153.216 151.947 221.443 1.00 37.43 ? 214 LEU B CD2 1 
ATOM   4909 N N   . ASP B 2 215 ? 151.453 149.286 217.592 1.00 38.71 ? 215 ASP B N   1 
ATOM   4910 C CA  . ASP B 2 215 ? 152.185 148.942 216.383 1.00 38.71 ? 215 ASP B CA  1 
ATOM   4911 C C   . ASP B 2 215 ? 152.802 150.178 215.741 1.00 38.71 ? 215 ASP B C   1 
ATOM   4912 O O   . ASP B 2 215 ? 152.194 151.248 215.697 1.00 38.71 ? 215 ASP B O   1 
ATOM   4913 C CB  . ASP B 2 215 ? 151.271 148.205 215.400 1.00 38.71 ? 215 ASP B CB  1 
ATOM   4914 C CG  . ASP B 2 215 ? 150.058 149.018 214.985 1.00 38.71 ? 215 ASP B CG  1 
ATOM   4915 O OD1 . ASP B 2 215 ? 149.863 150.136 215.496 1.00 38.71 ? 215 ASP B OD1 1 
ATOM   4916 O OD2 . ASP B 2 215 ? 149.286 148.528 214.137 1.00 38.71 ? 215 ASP B OD2 1 
ATOM   4917 N N   . ARG B 2 216 ? 154.037 150.030 215.272 1.00 26.17 ? 216 ARG B N   1 
ATOM   4918 C CA  . ARG B 2 216 ? 154.784 151.127 214.675 1.00 26.17 ? 216 ARG B CA  1 
ATOM   4919 C C   . ARG B 2 216 ? 154.764 151.091 213.156 1.00 26.17 ? 216 ARG B C   1 
ATOM   4920 O O   . ARG B 2 216 ? 155.495 151.856 212.522 1.00 26.17 ? 216 ARG B O   1 
ATOM   4921 C CB  . ARG B 2 216 ? 156.230 151.114 215.173 1.00 26.17 ? 216 ARG B CB  1 
ATOM   4922 N N   . PHE B 2 217 ? 153.947 150.225 212.556 1.00 22.83 ? 217 PHE B N   1 
ATOM   4923 C CA  . PHE B 2 217 ? 153.948 150.033 211.111 1.00 22.83 ? 217 PHE B CA  1 
ATOM   4924 C C   . PHE B 2 217 ? 152.995 150.973 210.387 1.00 22.83 ? 217 PHE B C   1 
ATOM   4925 O O   . PHE B 2 217 ? 152.556 150.663 209.272 1.00 22.83 ? 217 PHE B O   1 
ATOM   4926 C CB  . PHE B 2 217 ? 153.614 148.581 210.774 1.00 22.83 ? 217 PHE B CB  1 
ATOM   4927 C CG  . PHE B 2 217 ? 154.617 147.599 211.284 1.00 22.83 ? 217 PHE B CG  1 
ATOM   4928 C CD1 . PHE B 2 217 ? 155.734 147.287 210.540 1.00 22.83 ? 217 PHE B CD1 1 
ATOM   4929 C CD2 . PHE B 2 217 ? 154.436 146.978 212.502 1.00 22.83 ? 217 PHE B CD2 1 
ATOM   4930 C CE1 . PHE B 2 217 ? 156.655 146.384 211.004 1.00 22.83 ? 217 PHE B CE1 1 
ATOM   4931 C CE2 . PHE B 2 217 ? 155.357 146.071 212.971 1.00 22.83 ? 217 PHE B CE2 1 
ATOM   4932 C CZ  . PHE B 2 217 ? 156.468 145.775 212.222 1.00 22.83 ? 217 PHE B CZ  1 
ATOM   4933 N N   . LYS B 2 218 ? 152.662 152.112 210.982 1.00 25.71 ? 218 LYS B N   1 
ATOM   4934 C CA  . LYS B 2 218 ? 151.788 153.082 210.344 1.00 25.71 ? 218 LYS B CA  1 
ATOM   4935 C C   . LYS B 2 218 ? 152.382 154.470 210.506 1.00 25.71 ? 218 LYS B C   1 
ATOM   4936 O O   . LYS B 2 218 ? 153.132 154.734 211.449 1.00 25.71 ? 218 LYS B O   1 
ATOM   4937 C CB  . LYS B 2 218 ? 150.368 153.036 210.925 1.00 25.71 ? 218 LYS B CB  1 
ATOM   4938 C CG  . LYS B 2 218 ? 150.207 153.733 212.264 1.00 25.71 ? 218 LYS B CG  1 
ATOM   4939 C CD  . LYS B 2 218 ? 148.745 153.776 212.671 1.00 25.71 ? 218 LYS B CD  1 
ATOM   4940 C CE  . LYS B 2 218 ? 148.552 154.458 214.012 1.00 25.71 ? 218 LYS B CE  1 
ATOM   4941 N NZ  . LYS B 2 218 ? 149.407 153.862 215.064 1.00 25.71 ? 218 LYS B NZ  1 
ATOM   4942 N N   . GLU B 2 219 ? 152.049 155.350 209.571 1.00 26.51 ? 219 GLU B N   1 
ATOM   4943 C CA  . GLU B 2 219 ? 152.562 156.708 209.622 1.00 26.51 ? 219 GLU B CA  1 
ATOM   4944 C C   . GLU B 2 219 ? 152.055 157.401 210.884 1.00 26.51 ? 219 GLU B C   1 
ATOM   4945 O O   . GLU B 2 219 ? 150.878 157.259 211.234 1.00 26.51 ? 219 GLU B O   1 
ATOM   4946 C CB  . GLU B 2 219 ? 152.135 157.484 208.378 1.00 26.51 ? 219 GLU B CB  1 
ATOM   4947 C CG  . GLU B 2 219 ? 152.684 158.888 208.316 1.00 26.51 ? 219 GLU B CG  1 
ATOM   4948 C CD  . GLU B 2 219 ? 152.478 159.531 206.969 1.00 26.51 ? 219 GLU B CD  1 
ATOM   4949 O OE1 . GLU B 2 219 ? 151.954 158.855 206.061 1.00 26.51 ? 219 GLU B OE1 1 
ATOM   4950 O OE2 . GLU B 2 219 ? 152.848 160.711 206.816 1.00 26.51 ? 219 GLU B OE2 1 
ATOM   4951 N N   . PRO B 2 220 ? 152.910 158.131 211.598 1.00 27.91 ? 220 PRO B N   1 
ATOM   4952 C CA  . PRO B 2 220 ? 152.496 158.734 212.867 1.00 27.91 ? 220 PRO B CA  1 
ATOM   4953 C C   . PRO B 2 220 ? 151.286 159.630 212.683 1.00 27.91 ? 220 PRO B C   1 
ATOM   4954 O O   . PRO B 2 220 ? 151.229 160.429 211.737 1.00 27.91 ? 220 PRO B O   1 
ATOM   4955 C CB  . PRO B 2 220 ? 153.728 159.549 213.290 1.00 27.91 ? 220 PRO B CB  1 
ATOM   4956 C CG  . PRO B 2 220 ? 154.862 158.907 212.608 1.00 27.91 ? 220 PRO B CG  1 
ATOM   4957 C CD  . PRO B 2 220 ? 154.334 158.375 211.311 1.00 27.91 ? 220 PRO B CD  1 
ATOM   4958 N N   . PRO B 2 221 ? 150.303 159.530 213.566 1.00 26.58 ? 221 PRO B N   1 
ATOM   4959 C CA  . PRO B 2 221 ? 149.144 160.426 213.485 1.00 26.58 ? 221 PRO B CA  1 
ATOM   4960 C C   . PRO B 2 221 ? 149.500 161.833 213.928 1.00 26.58 ? 221 PRO B C   1 
ATOM   4961 O O   . PRO B 2 221 ? 150.674 162.134 214.154 1.00 26.58 ? 221 PRO B O   1 
ATOM   4962 C CB  . PRO B 2 221 ? 148.131 159.772 214.430 1.00 26.58 ? 221 PRO B CB  1 
ATOM   4963 C CG  . PRO B 2 221 ? 148.959 158.998 215.391 1.00 26.58 ? 221 PRO B CG  1 
ATOM   4964 C CD  . PRO B 2 221 ? 150.165 158.534 214.640 1.00 26.58 ? 221 PRO B CD  1 
ATOM   4965 N N   . ALA B 2 222 ? 148.508 162.713 214.035 1.00 26.38 ? 222 ALA B N   1 
ATOM   4966 C CA  . ALA B 2 222 ? 148.743 164.043 214.575 1.00 26.38 ? 222 ALA B CA  1 
ATOM   4967 C C   . ALA B 2 222 ? 148.587 164.102 216.087 1.00 26.38 ? 222 ALA B C   1 
ATOM   4968 O O   . ALA B 2 222 ? 148.917 165.128 216.689 1.00 26.38 ? 222 ALA B O   1 
ATOM   4969 C CB  . ALA B 2 222 ? 147.794 165.055 213.927 1.00 26.38 ? 222 ALA B CB  1 
ATOM   4970 N N   . TYR B 2 223 ? 148.104 163.028 216.708 1.00 28.84 ? 223 TYR B N   1 
ATOM   4971 C CA  . TYR B 2 223 ? 147.845 163.003 218.139 1.00 28.84 ? 223 TYR B CA  1 
ATOM   4972 C C   . TYR B 2 223 ? 147.943 161.570 218.633 1.00 28.84 ? 223 TYR B C   1 
ATOM   4973 O O   . TYR B 2 223 ? 147.815 160.617 217.860 1.00 28.84 ? 223 TYR B O   1 
ATOM   4974 C CB  . TYR B 2 223 ? 146.463 163.575 218.468 1.00 28.84 ? 223 TYR B CB  1 
ATOM   4975 C CG  . TYR B 2 223 ? 145.327 162.842 217.783 1.00 28.84 ? 223 TYR B CG  1 
ATOM   4976 C CD1 . TYR B 2 223 ? 145.001 163.106 216.459 1.00 28.84 ? 223 TYR B CD1 1 
ATOM   4977 C CD2 . TYR B 2 223 ? 144.582 161.888 218.462 1.00 28.84 ? 223 TYR B CD2 1 
ATOM   4978 C CE1 . TYR B 2 223 ? 143.970 162.441 215.832 1.00 28.84 ? 223 TYR B CE1 1 
ATOM   4979 C CE2 . TYR B 2 223 ? 143.547 161.218 217.841 1.00 28.84 ? 223 TYR B CE2 1 
ATOM   4980 C CZ  . TYR B 2 223 ? 143.246 161.500 216.526 1.00 28.84 ? 223 TYR B CZ  1 
ATOM   4981 O OH  . TYR B 2 223 ? 142.217 160.838 215.901 1.00 28.84 ? 223 TYR B OH  1 
ATOM   4982 N N   . GLY B 2 224 ? 148.161 161.424 219.935 1.00 28.07 ? 224 GLY B N   1 
ATOM   4983 C CA  . GLY B 2 224 ? 148.155 160.119 220.550 1.00 28.07 ? 224 GLY B CA  1 
ATOM   4984 C C   . GLY B 2 224 ? 149.459 159.774 221.234 1.00 28.07 ? 224 GLY B C   1 
ATOM   4985 O O   . GLY B 2 224 ? 150.290 160.639 221.517 1.00 28.07 ? 224 GLY B O   1 
ATOM   4986 N N   . PRO B 2 225 ? 149.654 158.488 221.530 1.00 23.03 ? 225 PRO B N   1 
ATOM   4987 C CA  . PRO B 2 225 ? 150.891 158.088 222.214 1.00 23.03 ? 225 PRO B CA  1 
ATOM   4988 C C   . PRO B 2 225 ? 152.109 158.100 221.311 1.00 23.03 ? 225 PRO B C   1 
ATOM   4989 O O   . PRO B 2 225 ? 153.178 158.547 221.739 1.00 23.03 ? 225 PRO B O   1 
ATOM   4990 C CB  . PRO B 2 225 ? 150.571 156.674 222.719 1.00 23.03 ? 225 PRO B CB  1 
ATOM   4991 C CG  . PRO B 2 225 ? 149.088 156.507 222.542 1.00 23.03 ? 225 PRO B CG  1 
ATOM   4992 C CD  . PRO B 2 225 ? 148.721 157.365 221.386 1.00 23.03 ? 225 PRO B CD  1 
ATOM   4993 N N   . MET B 2 226 ? 151.991 157.610 220.075 1.00 21.75 ? 226 MET B N   1 
ATOM   4994 C CA  . MET B 2 226 ? 153.148 157.609 219.187 1.00 21.75 ? 226 MET B CA  1 
ATOM   4995 C C   . MET B 2 226 ? 153.525 159.019 218.755 1.00 21.75 ? 226 MET B C   1 
ATOM   4996 O O   . MET B 2 226 ? 154.698 159.395 218.819 1.00 21.75 ? 226 MET B O   1 
ATOM   4997 C CB  . MET B 2 226 ? 152.890 156.732 217.965 1.00 21.75 ? 226 MET B CB  1 
ATOM   4998 C CG  . MET B 2 226 ? 154.151 156.418 217.187 1.00 21.75 ? 226 MET B CG  1 
ATOM   4999 S SD  . MET B 2 226 ? 153.850 155.538 215.650 1.00 21.75 ? 226 MET B SD  1 
ATOM   5000 C CE  . MET B 2 226 ? 152.350 154.671 216.066 1.00 21.75 ? 226 MET B CE  1 
ATOM   5001 N N   . CYS B 2 227 ? 152.553 159.816 218.316 1.00 17.78 ? 227 CYS B N   1 
ATOM   5002 C CA  . CYS B 2 227 ? 152.866 161.165 217.865 1.00 17.78 ? 227 CYS B CA  1 
ATOM   5003 C C   . CYS B 2 227 ? 153.443 162.026 218.972 1.00 17.78 ? 227 CYS B C   1 
ATOM   5004 O O   . CYS B 2 227 ? 154.159 162.985 218.680 1.00 17.78 ? 227 CYS B O   1 
ATOM   5005 C CB  . CYS B 2 227 ? 151.623 161.839 217.298 1.00 17.78 ? 227 CYS B CB  1 
ATOM   5006 S SG  . CYS B 2 227 ? 151.914 163.497 216.648 1.00 17.78 ? 227 CYS B SG  1 
ATOM   5007 N N   . ASP B 2 228 ? 153.153 161.716 220.228 1.00 15.44 ? 228 ASP B N   1 
ATOM   5008 C CA  . ASP B 2 228 ? 153.691 162.486 221.340 1.00 15.44 ? 228 ASP B CA  1 
ATOM   5009 C C   . ASP B 2 228 ? 155.037 161.967 221.823 1.00 15.44 ? 228 ASP B C   1 
ATOM   5010 O O   . ASP B 2 228 ? 155.624 162.566 222.729 1.00 15.44 ? 228 ASP B O   1 
ATOM   5011 C CB  . ASP B 2 228 ? 152.698 162.503 222.503 1.00 15.44 ? 228 ASP B CB  1 
ATOM   5012 N N   . ILE B 2 229 ? 155.537 160.873 221.249 1.00 14.32 ? 229 ILE B N   1 
ATOM   5013 C CA  . ILE B 2 229 ? 156.873 160.386 221.574 1.00 14.32 ? 229 ILE B CA  1 
ATOM   5014 C C   . ILE B 2 229 ? 157.906 160.862 220.561 1.00 14.32 ? 229 ILE B C   1 
ATOM   5015 O O   . ILE B 2 229 ? 159.106 160.853 220.869 1.00 14.32 ? 229 ILE B O   1 
ATOM   5016 C CB  . ILE B 2 229 ? 156.895 158.846 221.679 1.00 14.32 ? 229 ILE B CB  1 
ATOM   5017 C CG1 . ILE B 2 229 ? 158.012 158.380 222.600 1.00 14.32 ? 229 ILE B CG1 1 
ATOM   5018 C CG2 . ILE B 2 229 ? 157.136 158.216 220.340 1.00 14.32 ? 229 ILE B CG2 1 
ATOM   5019 C CD1 . ILE B 2 229 ? 157.896 156.933 222.964 1.00 14.32 ? 229 ILE B CD1 1 
ATOM   5020 N N   . LEU B 2 230 ? 157.482 161.292 219.378 1.00 12.30 ? 230 LEU B N   1 
ATOM   5021 C CA  . LEU B 2 230 ? 158.380 161.767 218.340 1.00 12.30 ? 230 LEU B CA  1 
ATOM   5022 C C   . LEU B 2 230 ? 158.279 163.268 218.123 1.00 12.30 ? 230 LEU B C   1 
ATOM   5023 O O   . LEU B 2 230 ? 159.056 163.818 217.342 1.00 12.30 ? 230 LEU B O   1 
ATOM   5024 C CB  . LEU B 2 230 ? 158.079 161.050 217.026 1.00 12.30 ? 230 LEU B CB  1 
ATOM   5025 C CG  . LEU B 2 230 ? 158.059 159.528 217.085 1.00 12.30 ? 230 LEU B CG  1 
ATOM   5026 C CD1 . LEU B 2 230 ? 157.614 158.956 215.758 1.00 12.30 ? 230 LEU B CD1 1 
ATOM   5027 C CD2 . LEU B 2 230 ? 159.408 158.996 217.476 1.00 12.30 ? 230 LEU B CD2 1 
ATOM   5028 N N   . TRP B 2 231 ? 157.335 163.941 218.777 1.00 15.37 ? 231 TRP B N   1 
ATOM   5029 C CA  . TRP B 2 231 ? 157.131 165.367 218.584 1.00 15.37 ? 231 TRP B CA  1 
ATOM   5030 C C   . TRP B 2 231 ? 157.277 166.188 219.853 1.00 15.37 ? 231 TRP B C   1 
ATOM   5031 O O   . TRP B 2 231 ? 157.422 167.409 219.755 1.00 15.37 ? 231 TRP B O   1 
ATOM   5032 C CB  . TRP B 2 231 ? 155.737 165.639 217.999 1.00 15.37 ? 231 TRP B CB  1 
ATOM   5033 C CG  . TRP B 2 231 ? 155.593 165.346 216.540 1.00 15.37 ? 231 TRP B CG  1 
ATOM   5034 C CD1 . TRP B 2 231 ? 155.156 164.185 215.978 1.00 15.37 ? 231 TRP B CD1 1 
ATOM   5035 C CD2 . TRP B 2 231 ? 155.860 166.239 215.456 1.00 15.37 ? 231 TRP B CD2 1 
ATOM   5036 N NE1 . TRP B 2 231 ? 155.145 164.295 214.612 1.00 15.37 ? 231 TRP B NE1 1 
ATOM   5037 C CE2 . TRP B 2 231 ? 155.573 165.548 214.266 1.00 15.37 ? 231 TRP B CE2 1 
ATOM   5038 C CE3 . TRP B 2 231 ? 156.320 167.556 215.377 1.00 15.37 ? 231 TRP B CE3 1 
ATOM   5039 C CZ2 . TRP B 2 231 ? 155.732 166.127 213.014 1.00 15.37 ? 231 TRP B CZ2 1 
ATOM   5040 C CZ3 . TRP B 2 231 ? 156.478 168.128 214.134 1.00 15.37 ? 231 TRP B CZ3 1 
ATOM   5041 C CH2 . TRP B 2 231 ? 156.186 167.415 212.968 1.00 15.37 ? 231 TRP B CH2 1 
ATOM   5042 N N   . SER B 2 232 ? 157.250 165.569 221.031 1.00 19.98 ? 232 SER B N   1 
ATOM   5043 C CA  . SER B 2 232 ? 157.238 166.312 222.285 1.00 19.98 ? 232 SER B CA  1 
ATOM   5044 C C   . SER B 2 232 ? 158.517 167.110 222.490 1.00 19.98 ? 232 SER B C   1 
ATOM   5045 O O   . SER B 2 232 ? 159.462 166.992 221.707 1.00 19.98 ? 232 SER B O   1 
ATOM   5046 C CB  . SER B 2 232 ? 157.028 165.366 223.461 1.00 19.98 ? 232 SER B CB  1 
ATOM   5047 O OG  . SER B 2 232 ? 157.366 166.009 224.672 1.00 19.98 ? 232 SER B OG  1 
ATOM   5048 N N   . ASP B 2 233 ? 158.558 167.921 223.540 1.00 29.28 ? 233 ASP B N   1 
ATOM   5049 C CA  . ASP B 2 233 ? 159.626 168.896 223.701 1.00 29.28 ? 233 ASP B CA  1 
ATOM   5050 C C   . ASP B 2 233 ? 159.570 169.395 225.143 1.00 29.28 ? 233 ASP B C   1 
ATOM   5051 O O   . ASP B 2 233 ? 158.491 169.786 225.601 1.00 29.28 ? 233 ASP B O   1 
ATOM   5052 C CB  . ASP B 2 233 ? 159.415 170.019 222.675 1.00 29.28 ? 233 ASP B CB  1 
ATOM   5053 C CG  . ASP B 2 233 ? 160.596 170.968 222.551 1.00 29.28 ? 233 ASP B CG  1 
ATOM   5054 O OD1 . ASP B 2 233 ? 161.599 170.811 223.265 1.00 29.28 ? 233 ASP B OD1 1 
ATOM   5055 O OD2 . ASP B 2 233 ? 160.519 171.881 221.704 1.00 29.28 ? 233 ASP B OD2 1 
ATOM   5056 N N   . PRO B 2 234 ? 160.668 169.393 225.897 1.00 36.42 ? 234 PRO B N   1 
ATOM   5057 C CA  . PRO B 2 234 ? 160.602 169.789 227.306 1.00 36.42 ? 234 PRO B CA  1 
ATOM   5058 C C   . PRO B 2 234 ? 160.678 171.295 227.519 1.00 36.42 ? 234 PRO B C   1 
ATOM   5059 O O   . PRO B 2 234 ? 161.119 172.056 226.657 1.00 36.42 ? 234 PRO B O   1 
ATOM   5060 C CB  . PRO B 2 234 ? 161.829 169.103 227.913 1.00 36.42 ? 234 PRO B CB  1 
ATOM   5061 C CG  . PRO B 2 234 ? 162.792 169.041 226.814 1.00 36.42 ? 234 PRO B CG  1 
ATOM   5062 C CD  . PRO B 2 234 ? 162.028 168.982 225.518 1.00 36.42 ? 234 PRO B CD  1 
ATOM   5063 N N   . LEU B 2 235 ? 160.245 171.707 228.710 1.00 51.69 ? 235 LEU B N   1 
ATOM   5064 C CA  . LEU B 2 235 ? 160.229 173.118 229.072 1.00 51.69 ? 235 LEU B CA  1 
ATOM   5065 C C   . LEU B 2 235 ? 161.639 173.686 229.141 1.00 51.69 ? 235 LEU B C   1 
ATOM   5066 O O   . LEU B 2 235 ? 162.602 172.989 229.469 1.00 51.69 ? 235 LEU B O   1 
ATOM   5067 C CB  . LEU B 2 235 ? 159.547 173.335 230.423 1.00 51.69 ? 235 LEU B CB  1 
ATOM   5068 C CG  . LEU B 2 235 ? 158.023 173.394 230.504 1.00 51.69 ? 235 LEU B CG  1 
ATOM   5069 C CD1 . LEU B 2 235 ? 157.434 172.012 230.381 1.00 51.69 ? 235 LEU B CD1 1 
ATOM   5070 C CD2 . LEU B 2 235 ? 157.586 174.045 231.803 1.00 51.69 ? 235 LEU B CD2 1 
ATOM   5071 N N   . GLU B 2 236 ? 161.747 174.975 228.844 1.00 70.22 ? 236 GLU B N   1 
ATOM   5072 C CA  . GLU B 2 236 ? 162.999 175.704 228.960 1.00 70.22 ? 236 GLU B CA  1 
ATOM   5073 C C   . GLU B 2 236 ? 163.221 176.261 230.359 1.00 70.22 ? 236 GLU B C   1 
ATOM   5074 O O   . GLU B 2 236 ? 164.261 176.878 230.611 1.00 70.22 ? 236 GLU B O   1 
ATOM   5075 C CB  . GLU B 2 236 ? 163.031 176.845 227.939 1.00 70.22 ? 236 GLU B CB  1 
ATOM   5076 C CG  . GLU B 2 236 ? 162.087 177.990 228.272 1.00 70.22 ? 236 GLU B CG  1 
ATOM   5077 C CD  . GLU B 2 236 ? 160.641 177.688 227.926 1.00 70.22 ? 236 GLU B CD  1 
ATOM   5078 O OE1 . GLU B 2 236 ? 160.321 176.516 227.640 1.00 70.22 ? 236 GLU B OE1 1 
ATOM   5079 O OE2 . GLU B 2 236 ? 159.817 178.626 227.946 1.00 70.22 ? 236 GLU B OE2 1 
ATOM   5080 N N   . ASP B 2 237 ? 162.270 176.059 231.268 1.00 70.16 ? 237 ASP B N   1 
ATOM   5081 C CA  . ASP B 2 237 ? 162.307 176.608 232.620 1.00 70.16 ? 237 ASP B CA  1 
ATOM   5082 C C   . ASP B 2 237 ? 161.927 175.543 233.642 1.00 70.16 ? 237 ASP B C   1 
ATOM   5083 O O   . ASP B 2 237 ? 161.020 175.732 234.456 1.00 70.16 ? 237 ASP B O   1 
ATOM   5084 C CB  . ASP B 2 237 ? 161.395 177.826 232.745 1.00 70.16 ? 237 ASP B CB  1 
ATOM   5085 C CG  . ASP B 2 237 ? 160.013 177.577 232.185 1.00 70.16 ? 237 ASP B CG  1 
ATOM   5086 O OD1 . ASP B 2 237 ? 159.860 176.636 231.379 1.00 70.16 ? 237 ASP B OD1 1 
ATOM   5087 O OD2 . ASP B 2 237 ? 159.080 178.320 232.553 1.00 70.16 ? 237 ASP B OD2 1 
ATOM   5088 N N   . PHE B 2 238 ? 162.589 174.383 233.570 1.00 65.70 ? 238 PHE B N   1 
ATOM   5089 C CA  . PHE B 2 238 ? 162.433 173.335 234.578 1.00 65.70 ? 238 PHE B CA  1 
ATOM   5090 C C   . PHE B 2 238 ? 162.416 173.916 235.986 1.00 65.70 ? 238 PHE B C   1 
ATOM   5091 O O   . PHE B 2 238 ? 163.274 174.721 236.357 1.00 65.70 ? 238 PHE B O   1 
ATOM   5092 C CB  . PHE B 2 238 ? 163.560 172.307 234.449 1.00 65.70 ? 238 PHE B CB  1 
ATOM   5093 C CG  . PHE B 2 238 ? 163.302 171.248 233.415 1.00 65.70 ? 238 PHE B CG  1 
ATOM   5094 C CD1 . PHE B 2 238 ? 162.734 170.039 233.779 1.00 65.70 ? 238 PHE B CD1 1 
ATOM   5095 C CD2 . PHE B 2 238 ? 163.608 171.458 232.086 1.00 65.70 ? 238 PHE B CD2 1 
ATOM   5096 C CE1 . PHE B 2 238 ? 162.489 169.054 232.845 1.00 65.70 ? 238 PHE B CE1 1 
ATOM   5097 C CE2 . PHE B 2 238 ? 163.361 170.473 231.146 1.00 65.70 ? 238 PHE B CE2 1 
ATOM   5098 C CZ  . PHE B 2 238 ? 162.801 169.271 231.530 1.00 65.70 ? 238 PHE B CZ  1 
ATOM   5099 N N   . GLY B 2 239 ? 161.426 173.496 236.768 1.00 70.75 ? 239 GLY B N   1 
ATOM   5100 C CA  . GLY B 2 239 ? 161.136 174.132 238.035 1.00 70.75 ? 239 GLY B CA  1 
ATOM   5101 C C   . GLY B 2 239 ? 160.048 175.177 237.973 1.00 70.75 ? 239 GLY B C   1 
ATOM   5102 O O   . GLY B 2 239 ? 159.872 175.927 238.940 1.00 70.75 ? 239 GLY B O   1 
ATOM   5103 N N   . ASN B 2 240 ? 159.313 175.250 236.866 1.00 68.57 ? 240 ASN B N   1 
ATOM   5104 C CA  . ASN B 2 240 ? 158.268 176.252 236.710 1.00 68.57 ? 240 ASN B CA  1 
ATOM   5105 C C   . ASN B 2 240 ? 157.120 175.986 237.676 1.00 68.57 ? 240 ASN B C   1 
ATOM   5106 O O   . ASN B 2 240 ? 156.831 174.838 238.024 1.00 68.57 ? 240 ASN B O   1 
ATOM   5107 C CB  . ASN B 2 240 ? 157.766 176.255 235.264 1.00 68.57 ? 240 ASN B CB  1 
ATOM   5108 C CG  . ASN B 2 240 ? 156.459 177.001 235.097 1.00 68.57 ? 240 ASN B CG  1 
ATOM   5109 O OD1 . ASN B 2 240 ? 155.390 176.396 235.028 1.00 68.57 ? 240 ASN B OD1 1 
ATOM   5110 N ND2 . ASN B 2 240 ? 156.539 178.325 235.030 1.00 68.57 ? 240 ASN B ND2 1 
ATOM   5111 N N   . GLU B 2 241 ? 156.471 177.062 238.117 1.00 65.33 ? 241 GLU B N   1 
ATOM   5112 C CA  . GLU B 2 241 ? 155.375 176.982 239.074 1.00 65.33 ? 241 GLU B CA  1 
ATOM   5113 C C   . GLU B 2 241 ? 154.229 176.136 238.537 1.00 65.33 ? 241 GLU B C   1 
ATOM   5114 O O   . GLU B 2 241 ? 153.897 176.196 237.349 1.00 65.33 ? 241 GLU B O   1 
ATOM   5115 C CB  . GLU B 2 241 ? 154.880 178.393 239.409 1.00 65.33 ? 241 GLU B CB  1 
ATOM   5116 C CG  . GLU B 2 241 ? 154.275 179.148 238.234 1.00 65.33 ? 241 GLU B CG  1 
ATOM   5117 C CD  . GLU B 2 241 ? 155.305 179.935 237.450 1.00 65.33 ? 241 GLU B CD  1 
ATOM   5118 O OE1 . GLU B 2 241 ? 156.514 179.701 237.651 1.00 65.33 ? 241 GLU B OE1 1 
ATOM   5119 O OE2 . GLU B 2 241 ? 154.905 180.786 236.628 1.00 65.33 ? 241 GLU B OE2 1 
ATOM   5120 N N   . LYS B 2 242 ? 153.631 175.335 239.412 1.00 60.51 ? 242 LYS B N   1 
ATOM   5121 C CA  . LYS B 2 242 ? 152.523 174.473 239.023 1.00 60.51 ? 242 LYS B CA  1 
ATOM   5122 C C   . LYS B 2 242 ? 151.195 175.215 239.109 1.00 60.51 ? 242 LYS B C   1 
ATOM   5123 O O   . LYS B 2 242 ? 150.624 175.605 238.091 1.00 60.51 ? 242 LYS B O   1 
ATOM   5124 C CB  . LYS B 2 242 ? 152.484 173.221 239.900 1.00 60.51 ? 242 LYS B CB  1 
ATOM   5125 N N   . HIS B 2 246 ? 154.118 169.257 232.797 1.00 47.26 ? 246 HIS B N   1 
ATOM   5126 C CA  . HIS B 2 246 ? 153.233 168.102 232.856 1.00 47.26 ? 246 HIS B CA  1 
ATOM   5127 C C   . HIS B 2 246 ? 152.541 167.834 231.525 1.00 47.26 ? 246 HIS B C   1 
ATOM   5128 O O   . HIS B 2 246 ? 152.901 166.899 230.811 1.00 47.26 ? 246 HIS B O   1 
ATOM   5129 C CB  . HIS B 2 246 ? 152.190 168.286 233.957 1.00 47.26 ? 246 HIS B CB  1 
ATOM   5130 C CG  . HIS B 2 246 ? 152.541 167.600 235.240 1.00 47.26 ? 246 HIS B CG  1 
ATOM   5131 N ND1 . HIS B 2 246 ? 152.282 166.265 235.464 1.00 47.26 ? 246 HIS B ND1 1 
ATOM   5132 C CD2 . HIS B 2 246 ? 153.136 168.061 236.365 1.00 47.26 ? 246 HIS B CD2 1 
ATOM   5133 C CE1 . HIS B 2 246 ? 152.699 165.934 236.672 1.00 47.26 ? 246 HIS B CE1 1 
ATOM   5134 N NE2 . HIS B 2 246 ? 153.221 167.005 237.240 1.00 47.26 ? 246 HIS B NE2 1 
ATOM   5135 N N   . PHE B 2 247 ? 151.538 168.647 231.196 1.00 44.33 ? 247 PHE B N   1 
ATOM   5136 C CA  . PHE B 2 247 ? 150.775 168.432 229.974 1.00 44.33 ? 247 PHE B CA  1 
ATOM   5137 C C   . PHE B 2 247 ? 150.436 169.745 229.278 1.00 44.33 ? 247 PHE B C   1 
ATOM   5138 O O   . PHE B 2 247 ? 149.433 169.830 228.561 1.00 44.33 ? 247 PHE B O   1 
ATOM   5139 C CB  . PHE B 2 247 ? 149.493 167.647 230.259 1.00 44.33 ? 247 PHE B CB  1 
ATOM   5140 N N   . THR B 2 248 ? 151.249 170.775 229.476 1.00 38.46 ? 248 THR B N   1 
ATOM   5141 C CA  . THR B 2 248 ? 151.033 172.036 228.782 1.00 38.46 ? 248 THR B CA  1 
ATOM   5142 C C   . THR B 2 248 ? 151.382 171.883 227.308 1.00 38.46 ? 248 THR B C   1 
ATOM   5143 O O   . THR B 2 248 ? 152.438 171.343 226.969 1.00 38.46 ? 248 THR B O   1 
ATOM   5144 C CB  . THR B 2 248 ? 151.883 173.134 229.410 1.00 38.46 ? 248 THR B CB  1 
ATOM   5145 O OG1 . THR B 2 248 ? 153.265 172.767 229.329 1.00 38.46 ? 248 THR B OG1 1 
ATOM   5146 C CG2 . THR B 2 248 ? 151.505 173.322 230.867 1.00 38.46 ? 248 THR B CG2 1 
ATOM   5147 N N   . HIS B 2 249 ? 150.504 172.362 226.430 1.00 35.43 ? 249 HIS B N   1 
ATOM   5148 C CA  . HIS B 2 249 ? 150.766 172.267 225.001 1.00 35.43 ? 249 HIS B CA  1 
ATOM   5149 C C   . HIS B 2 249 ? 151.972 173.120 224.622 1.00 35.43 ? 249 HIS B C   1 
ATOM   5150 O O   . HIS B 2 249 ? 152.426 173.978 225.381 1.00 35.43 ? 249 HIS B O   1 
ATOM   5151 C CB  . HIS B 2 249 ? 149.558 172.720 224.185 1.00 35.43 ? 249 HIS B CB  1 
ATOM   5152 C CG  . HIS B 2 249 ? 148.303 171.960 224.472 1.00 35.43 ? 249 HIS B CG  1 
ATOM   5153 N ND1 . HIS B 2 249 ? 147.978 171.524 225.737 1.00 35.43 ? 249 HIS B ND1 1 
ATOM   5154 C CD2 . HIS B 2 249 ? 147.305 171.540 223.660 1.00 35.43 ? 249 HIS B CD2 1 
ATOM   5155 C CE1 . HIS B 2 249 ? 146.828 170.876 225.694 1.00 35.43 ? 249 HIS B CE1 1 
ATOM   5156 N NE2 . HIS B 2 249 ? 146.398 170.871 224.446 1.00 35.43 ? 249 HIS B NE2 1 
ATOM   5157 N N   . ASN B 2 250 ? 152.496 172.872 223.427 1.00 34.09 ? 250 ASN B N   1 
ATOM   5158 C CA  . ASN B 2 250 ? 153.597 173.661 222.903 1.00 34.09 ? 250 ASN B CA  1 
ATOM   5159 C C   . ASN B 2 250 ? 153.138 174.474 221.701 1.00 34.09 ? 250 ASN B C   1 
ATOM   5160 O O   . ASN B 2 250 ? 152.153 174.147 221.034 1.00 34.09 ? 250 ASN B O   1 
ATOM   5161 C CB  . ASN B 2 250 ? 154.792 172.777 222.524 1.00 34.09 ? 250 ASN B CB  1 
ATOM   5162 C CG  . ASN B 2 250 ? 154.472 171.778 221.433 1.00 34.09 ? 250 ASN B CG  1 
ATOM   5163 O OD1 . ASN B 2 250 ? 153.343 171.694 220.955 1.00 34.09 ? 250 ASN B OD1 1 
ATOM   5164 N ND2 . ASN B 2 250 ? 155.480 171.018 221.021 1.00 34.09 ? 250 ASN B ND2 1 
ATOM   5165 N N   . THR B 2 251 ? 153.862 175.559 221.445 1.00 35.94 ? 251 THR B N   1 
ATOM   5166 C CA  . THR B 2 251 ? 153.612 176.412 220.294 1.00 35.94 ? 251 THR B CA  1 
ATOM   5167 C C   . THR B 2 251 ? 154.669 176.287 219.211 1.00 35.94 ? 251 THR B C   1 
ATOM   5168 O O   . THR B 2 251 ? 154.374 176.559 218.047 1.00 35.94 ? 251 THR B O   1 
ATOM   5169 C CB  . THR B 2 251 ? 153.521 177.880 220.727 1.00 35.94 ? 251 THR B CB  1 
ATOM   5170 O OG1 . THR B 2 251 ? 154.797 178.315 221.211 1.00 35.94 ? 251 THR B OG1 1 
ATOM   5171 C CG2 . THR B 2 251 ? 152.490 178.043 221.828 1.00 35.94 ? 251 THR B CG2 1 
ATOM   5172 N N   . VAL B 2 252 ? 155.890 175.882 219.568 1.00 30.82 ? 252 VAL B N   1 
ATOM   5173 C CA  . VAL B 2 252 ? 156.953 175.755 218.576 1.00 30.82 ? 252 VAL B CA  1 
ATOM   5174 C C   . VAL B 2 252 ? 156.589 174.701 217.540 1.00 30.82 ? 252 VAL B C   1 
ATOM   5175 O O   . VAL B 2 252 ? 156.738 174.918 216.332 1.00 30.82 ? 252 VAL B O   1 
ATOM   5176 C CB  . VAL B 2 252 ? 158.290 175.437 219.270 1.00 30.82 ? 252 VAL B CB  1 
ATOM   5177 C CG1 . VAL B 2 252 ? 159.377 175.202 218.241 1.00 30.82 ? 252 VAL B CG1 1 
ATOM   5178 C CG2 . VAL B 2 252 ? 158.676 176.560 220.215 1.00 30.82 ? 252 VAL B CG2 1 
ATOM   5179 N N   . ARG B 2 253 ? 156.102 173.548 217.991 1.00 30.55 ? 253 ARG B N   1 
ATOM   5180 C CA  . ARG B 2 253 ? 155.555 172.539 217.094 1.00 30.55 ? 253 ARG B CA  1 
ATOM   5181 C C   . ARG B 2 253 ? 154.051 172.671 216.912 1.00 30.55 ? 253 ARG B C   1 
ATOM   5182 O O   . ARG B 2 253 ? 153.552 172.536 215.791 1.00 30.55 ? 253 ARG B O   1 
ATOM   5183 C CB  . ARG B 2 253 ? 155.870 171.126 217.605 1.00 30.55 ? 253 ARG B CB  1 
ATOM   5184 C CG  . ARG B 2 253 ? 157.199 170.547 217.145 1.00 30.55 ? 253 ARG B CG  1 
ATOM   5185 C CD  . ARG B 2 253 ? 158.379 171.190 217.838 1.00 30.55 ? 253 ARG B CD  1 
ATOM   5186 N NE  . ARG B 2 253 ? 159.630 170.528 217.490 1.00 30.55 ? 253 ARG B NE  1 
ATOM   5187 C CZ  . ARG B 2 253 ? 160.826 170.933 217.899 1.00 30.55 ? 253 ARG B CZ  1 
ATOM   5188 N NH1 . ARG B 2 253 ? 160.938 171.994 218.682 1.00 30.55 ? 253 ARG B NH1 1 
ATOM   5189 N NH2 . ARG B 2 253 ? 161.911 170.273 217.533 1.00 30.55 ? 253 ARG B NH2 1 
ATOM   5190 N N   . GLY B 2 254 ? 153.320 172.941 217.989 1.00 29.06 ? 254 GLY B N   1 
ATOM   5191 C CA  . GLY B 2 254 ? 151.870 172.944 217.928 1.00 29.06 ? 254 GLY B CA  1 
ATOM   5192 C C   . GLY B 2 254 ? 151.279 171.590 217.619 1.00 29.06 ? 254 GLY B C   1 
ATOM   5193 O O   . GLY B 2 254 ? 150.217 171.512 216.993 1.00 29.06 ? 254 GLY B O   1 
ATOM   5194 N N   . CYS B 2 255 ? 151.941 170.512 218.040 1.00 28.96 ? 255 CYS B N   1 
ATOM   5195 C CA  . CYS B 2 255 ? 151.464 169.174 217.729 1.00 28.96 ? 255 CYS B CA  1 
ATOM   5196 C C   . CYS B 2 255 ? 151.562 168.182 218.881 1.00 28.96 ? 255 CYS B C   1 
ATOM   5197 O O   . CYS B 2 255 ? 151.124 167.040 218.716 1.00 28.96 ? 255 CYS B O   1 
ATOM   5198 C CB  . CYS B 2 255 ? 152.225 168.613 216.516 1.00 28.96 ? 255 CYS B CB  1 
ATOM   5199 S SG  . CYS B 2 255 ? 151.963 169.532 214.978 1.00 28.96 ? 255 CYS B SG  1 
ATOM   5200 N N   . SER B 2 256 ? 152.110 168.563 220.027 1.00 28.29 ? 256 SER B N   1 
ATOM   5201 C CA  . SER B 2 256 ? 152.218 167.649 221.159 1.00 28.29 ? 256 SER B CA  1 
ATOM   5202 C C   . SER B 2 256 ? 152.461 168.470 222.418 1.00 28.29 ? 256 SER B C   1 
ATOM   5203 O O   . SER B 2 256 ? 152.339 169.697 222.418 1.00 28.29 ? 256 SER B O   1 
ATOM   5204 C CB  . SER B 2 256 ? 153.319 166.616 220.942 1.00 28.29 ? 256 SER B CB  1 
ATOM   5205 O OG  . SER B 2 256 ? 153.008 165.785 219.841 1.00 28.29 ? 256 SER B OG  1 
ATOM   5206 N N   . TYR B 2 257 ? 152.816 167.781 223.493 1.00 27.67 ? 257 TYR B N   1 
ATOM   5207 C CA  . TYR B 2 257 ? 152.833 168.369 224.820 1.00 27.67 ? 257 TYR B CA  1 
ATOM   5208 C C   . TYR B 2 257 ? 154.250 168.660 225.291 1.00 27.67 ? 257 TYR B C   1 
ATOM   5209 O O   . TYR B 2 257 ? 155.200 167.958 224.945 1.00 27.67 ? 257 TYR B O   1 
ATOM   5210 C CB  . TYR B 2 257 ? 152.146 167.440 225.821 1.00 27.67 ? 257 TYR B CB  1 
ATOM   5211 C CG  . TYR B 2 257 ? 150.695 167.173 225.504 1.00 27.67 ? 257 TYR B CG  1 
ATOM   5212 C CD1 . TYR B 2 257 ? 150.333 166.254 224.532 1.00 27.67 ? 257 TYR B CD1 1 
ATOM   5213 C CD2 . TYR B 2 257 ? 149.687 167.827 226.190 1.00 27.67 ? 257 TYR B CD2 1 
ATOM   5214 C CE1 . TYR B 2 257 ? 149.009 166.009 224.241 1.00 27.67 ? 257 TYR B CE1 1 
ATOM   5215 C CE2 . TYR B 2 257 ? 148.361 167.587 225.908 1.00 27.67 ? 257 TYR B CE2 1 
ATOM   5216 C CZ  . TYR B 2 257 ? 148.027 166.677 224.933 1.00 27.67 ? 257 TYR B CZ  1 
ATOM   5217 O OH  . TYR B 2 257 ? 146.703 166.435 224.650 1.00 27.67 ? 257 TYR B OH  1 
ATOM   5218 N N   . PHE B 2 258 ? 154.378 169.716 226.088 1.00 35.30 ? 258 PHE B N   1 
ATOM   5219 C CA  . PHE B 2 258 ? 155.557 169.918 226.909 1.00 35.30 ? 258 PHE B CA  1 
ATOM   5220 C C   . PHE B 2 258 ? 155.581 168.864 228.014 1.00 35.30 ? 258 PHE B C   1 
ATOM   5221 O O   . PHE B 2 258 ? 154.691 168.016 228.119 1.00 35.30 ? 258 PHE B O   1 
ATOM   5222 C CB  . PHE B 2 258 ? 155.550 171.320 227.513 1.00 35.30 ? 258 PHE B CB  1 
ATOM   5223 C CG  . PHE B 2 258 ? 156.297 172.349 226.710 1.00 35.30 ? 258 PHE B CG  1 
ATOM   5224 C CD1 . PHE B 2 258 ? 157.673 172.419 226.757 1.00 35.30 ? 258 PHE B CD1 1 
ATOM   5225 C CD2 . PHE B 2 258 ? 155.617 173.269 225.931 1.00 35.30 ? 258 PHE B CD2 1 
ATOM   5226 C CE1 . PHE B 2 258 ? 158.358 173.371 226.027 1.00 35.30 ? 258 PHE B CE1 1 
ATOM   5227 C CE2 . PHE B 2 258 ? 156.302 174.225 225.202 1.00 35.30 ? 258 PHE B CE2 1 
ATOM   5228 C CZ  . PHE B 2 258 ? 157.671 174.273 225.249 1.00 35.30 ? 258 PHE B CZ  1 
ATOM   5229 N N   . TYR B 2 259 ? 156.611 168.915 228.856 1.00 32.52 ? 259 TYR B N   1 
ATOM   5230 C CA  . TYR B 2 259 ? 156.630 168.110 230.072 1.00 32.52 ? 259 TYR B CA  1 
ATOM   5231 C C   . TYR B 2 259 ? 157.679 168.683 231.009 1.00 32.52 ? 259 TYR B C   1 
ATOM   5232 O O   . TYR B 2 259 ? 158.818 168.914 230.598 1.00 32.52 ? 259 TYR B O   1 
ATOM   5233 C CB  . TYR B 2 259 ? 156.898 166.624 229.776 1.00 32.52 ? 259 TYR B CB  1 
ATOM   5234 C CG  . TYR B 2 259 ? 158.185 166.315 229.044 1.00 32.52 ? 259 TYR B CG  1 
ATOM   5235 C CD1 . TYR B 2 259 ? 158.222 166.255 227.663 1.00 32.52 ? 259 TYR B CD1 1 
ATOM   5236 C CD2 . TYR B 2 259 ? 159.352 166.045 229.738 1.00 32.52 ? 259 TYR B CD2 1 
ATOM   5237 C CE1 . TYR B 2 259 ? 159.389 165.966 226.996 1.00 32.52 ? 259 TYR B CE1 1 
ATOM   5238 C CE2 . TYR B 2 259 ? 160.521 165.754 229.078 1.00 32.52 ? 259 TYR B CE2 1 
ATOM   5239 C CZ  . TYR B 2 259 ? 160.533 165.716 227.710 1.00 32.52 ? 259 TYR B CZ  1 
ATOM   5240 O OH  . TYR B 2 259 ? 161.701 165.423 227.053 1.00 32.52 ? 259 TYR B OH  1 
ATOM   5241 N N   . SER B 2 260 ? 157.287 168.930 232.254 1.00 44.98 ? 260 SER B N   1 
ATOM   5242 C CA  . SER B 2 260 ? 158.160 169.593 233.205 1.00 44.98 ? 260 SER B CA  1 
ATOM   5243 C C   . SER B 2 260 ? 158.905 168.571 234.060 1.00 44.98 ? 260 SER B C   1 
ATOM   5244 O O   . SER B 2 260 ? 158.736 167.358 233.923 1.00 44.98 ? 260 SER B O   1 
ATOM   5245 C CB  . SER B 2 260 ? 157.361 170.555 234.082 1.00 44.98 ? 260 SER B CB  1 
ATOM   5246 O OG  . SER B 2 260 ? 158.214 171.257 234.970 1.00 44.98 ? 260 SER B OG  1 
ATOM   5247 N N   . TYR B 2 261 ? 159.741 169.082 234.961 1.00 49.10 ? 261 TYR B N   1 
ATOM   5248 C CA  . TYR B 2 261 ? 160.539 168.223 235.832 1.00 49.10 ? 261 TYR B CA  1 
ATOM   5249 C C   . TYR B 2 261 ? 159.717 167.217 236.628 1.00 49.10 ? 261 TYR B C   1 
ATOM   5250 O O   . TYR B 2 261 ? 160.160 166.061 236.742 1.00 49.10 ? 261 TYR B O   1 
ATOM   5251 C CB  . TYR B 2 261 ? 161.378 169.099 236.775 1.00 49.10 ? 261 TYR B CB  1 
ATOM   5252 C CG  . TYR B 2 261 ? 162.283 168.323 237.698 1.00 49.10 ? 261 TYR B CG  1 
ATOM   5253 C CD1 . TYR B 2 261 ? 163.455 167.751 237.230 1.00 49.10 ? 261 TYR B CD1 1 
ATOM   5254 C CD2 . TYR B 2 261 ? 161.965 168.161 239.037 1.00 49.10 ? 261 TYR B CD2 1 
ATOM   5255 C CE1 . TYR B 2 261 ? 164.287 167.044 238.068 1.00 49.10 ? 261 TYR B CE1 1 
ATOM   5256 C CE2 . TYR B 2 261 ? 162.790 167.454 239.884 1.00 49.10 ? 261 TYR B CE2 1 
ATOM   5257 C CZ  . TYR B 2 261 ? 163.949 166.898 239.394 1.00 49.10 ? 261 TYR B CZ  1 
ATOM   5258 O OH  . TYR B 2 261 ? 164.774 166.192 240.236 1.00 49.10 ? 261 TYR B OH  1 
ATOM   5259 N N   . PRO B 2 262 ? 158.565 167.565 237.212 1.00 46.42 ? 262 PRO B N   1 
ATOM   5260 C CA  . PRO B 2 262 ? 157.787 166.540 237.923 1.00 46.42 ? 262 PRO B CA  1 
ATOM   5261 C C   . PRO B 2 262 ? 157.386 165.363 237.057 1.00 46.42 ? 262 PRO B C   1 
ATOM   5262 O O   . PRO B 2 262 ? 157.359 164.236 237.559 1.00 46.42 ? 262 PRO B O   1 
ATOM   5263 C CB  . PRO B 2 262 ? 156.563 167.316 238.422 1.00 46.42 ? 262 PRO B CB  1 
ATOM   5264 C CG  . PRO B 2 262 ? 157.049 168.704 238.569 1.00 46.42 ? 262 PRO B CG  1 
ATOM   5265 C CD  . PRO B 2 262 ? 158.005 168.912 237.435 1.00 46.42 ? 262 PRO B CD  1 
ATOM   5266 N N   . ALA B 2 263 ? 157.086 165.574 235.773 1.00 41.14 ? 263 ALA B N   1 
ATOM   5267 C CA  . ALA B 2 263 ? 156.675 164.456 234.927 1.00 41.14 ? 263 ALA B CA  1 
ATOM   5268 C C   . ALA B 2 263 ? 157.805 163.447 234.755 1.00 41.14 ? 263 ALA B C   1 
ATOM   5269 O O   . ALA B 2 263 ? 157.610 162.241 234.949 1.00 41.14 ? 263 ALA B O   1 
ATOM   5270 C CB  . ALA B 2 263 ? 156.201 164.969 233.569 1.00 41.14 ? 263 ALA B CB  1 
ATOM   5271 N N   . VAL B 2 264 ? 158.999 163.927 234.403 1.00 36.75 ? 264 VAL B N   1 
ATOM   5272 C CA  . VAL B 2 264 ? 160.143 163.035 234.244 1.00 36.75 ? 264 VAL B CA  1 
ATOM   5273 C C   . VAL B 2 264 ? 160.499 162.383 235.573 1.00 36.75 ? 264 VAL B C   1 
ATOM   5274 O O   . VAL B 2 264 ? 160.829 161.191 235.628 1.00 36.75 ? 264 VAL B O   1 
ATOM   5275 C CB  . VAL B 2 264 ? 161.338 163.800 233.645 1.00 36.75 ? 264 VAL B CB  1 
ATOM   5276 C CG1 . VAL B 2 264 ? 162.618 163.007 233.807 1.00 36.75 ? 264 VAL B CG1 1 
ATOM   5277 C CG2 . VAL B 2 264 ? 161.089 164.089 232.183 1.00 36.75 ? 264 VAL B CG2 1 
ATOM   5278 N N   . CYS B 2 265 ? 160.446 163.148 236.666 1.00 42.48 ? 265 CYS B N   1 
ATOM   5279 C CA  . CYS B 2 265 ? 160.789 162.582 237.965 1.00 42.48 ? 265 CYS B CA  1 
ATOM   5280 C C   . CYS B 2 265 ? 159.819 161.476 238.359 1.00 42.48 ? 265 CYS B C   1 
ATOM   5281 O O   . CYS B 2 265 ? 160.233 160.437 238.882 1.00 42.48 ? 265 CYS B O   1 
ATOM   5282 C CB  . CYS B 2 265 ? 160.821 163.678 239.028 1.00 42.48 ? 265 CYS B CB  1 
ATOM   5283 S SG  . CYS B 2 265 ? 161.505 163.145 240.613 1.00 42.48 ? 265 CYS B SG  1 
ATOM   5284 N N   . ASP B 2 266 ? 158.525 161.672 238.103 1.00 40.18 ? 266 ASP B N   1 
ATOM   5285 C CA  . ASP B 2 266 ? 157.549 160.634 238.417 1.00 40.18 ? 266 ASP B CA  1 
ATOM   5286 C C   . ASP B 2 266 ? 157.721 159.424 237.509 1.00 40.18 ? 266 ASP B C   1 
ATOM   5287 O O   . ASP B 2 266 ? 157.532 158.283 237.946 1.00 40.18 ? 266 ASP B O   1 
ATOM   5288 C CB  . ASP B 2 266 ? 156.134 161.193 238.302 1.00 40.18 ? 266 ASP B CB  1 
ATOM   5289 C CG  . ASP B 2 266 ? 155.151 160.465 239.191 1.00 40.18 ? 266 ASP B CG  1 
ATOM   5290 O OD1 . ASP B 2 266 ? 155.588 159.600 239.976 1.00 40.18 ? 266 ASP B OD1 1 
ATOM   5291 O OD2 . ASP B 2 266 ? 153.940 160.757 239.105 1.00 40.18 ? 266 ASP B OD2 1 
ATOM   5292 N N   . PHE B 2 267 ? 158.073 159.653 236.242 1.00 34.74 ? 267 PHE B N   1 
ATOM   5293 C CA  . PHE B 2 267 ? 158.310 158.541 235.327 1.00 34.74 ? 267 PHE B CA  1 
ATOM   5294 C C   . PHE B 2 267 ? 159.508 157.708 235.765 1.00 34.74 ? 267 PHE B C   1 
ATOM   5295 O O   . PHE B 2 267 ? 159.487 156.476 235.666 1.00 34.74 ? 267 PHE B O   1 
ATOM   5296 C CB  . PHE B 2 267 ? 158.511 159.075 233.912 1.00 34.74 ? 267 PHE B CB  1 
ATOM   5297 C CG  . PHE B 2 267 ? 158.652 158.010 232.872 1.00 34.74 ? 267 PHE B CG  1 
ATOM   5298 C CD1 . PHE B 2 267 ? 157.544 157.332 232.405 1.00 34.74 ? 267 PHE B CD1 1 
ATOM   5299 C CD2 . PHE B 2 267 ? 159.887 157.704 232.342 1.00 34.74 ? 267 PHE B CD2 1 
ATOM   5300 C CE1 . PHE B 2 267 ? 157.670 156.361 231.439 1.00 34.74 ? 267 PHE B CE1 1 
ATOM   5301 C CE2 . PHE B 2 267 ? 160.016 156.734 231.376 1.00 34.74 ? 267 PHE B CE2 1 
ATOM   5302 C CZ  . PHE B 2 267 ? 158.907 156.061 230.924 1.00 34.74 ? 267 PHE B CZ  1 
ATOM   5303 N N   . LEU B 2 268 ? 160.565 158.363 236.246 1.00 36.21 ? 268 LEU B N   1 
ATOM   5304 C CA  . LEU B 2 268 ? 161.751 157.662 236.725 1.00 36.21 ? 268 LEU B CA  1 
ATOM   5305 C C   . LEU B 2 268 ? 161.604 157.126 238.140 1.00 36.21 ? 268 LEU B C   1 
ATOM   5306 O O   . LEU B 2 268 ? 162.430 156.312 238.563 1.00 36.21 ? 268 LEU B O   1 
ATOM   5307 C CB  . LEU B 2 268 ? 162.968 158.580 236.664 1.00 36.21 ? 268 LEU B CB  1 
ATOM   5308 C CG  . LEU B 2 268 ? 163.285 159.113 235.274 1.00 36.21 ? 268 LEU B CG  1 
ATOM   5309 C CD1 . LEU B 2 268 ? 164.662 159.735 235.260 1.00 36.21 ? 268 LEU B CD1 1 
ATOM   5310 C CD2 . LEU B 2 268 ? 163.200 157.977 234.278 1.00 36.21 ? 268 LEU B CD2 1 
ATOM   5311 N N   . GLN B 2 269 ? 160.605 157.575 238.890 1.00 46.95 ? 269 GLN B N   1 
ATOM   5312 C CA  . GLN B 2 269 ? 160.353 156.987 240.197 1.00 46.95 ? 269 GLN B CA  1 
ATOM   5313 C C   . GLN B 2 269 ? 159.443 155.771 240.102 1.00 46.95 ? 269 GLN B C   1 
ATOM   5314 O O   . GLN B 2 269 ? 159.680 154.767 240.781 1.00 46.95 ? 269 GLN B O   1 
ATOM   5315 C CB  . GLN B 2 269 ? 159.742 158.029 241.135 1.00 46.95 ? 269 GLN B CB  1 
ATOM   5316 C CG  . GLN B 2 269 ? 159.799 157.644 242.597 1.00 46.95 ? 269 GLN B CG  1 
ATOM   5317 C CD  . GLN B 2 269 ? 161.221 157.498 243.094 1.00 46.95 ? 269 GLN B CD  1 
ATOM   5318 O OE1 . GLN B 2 269 ? 161.690 156.389 243.351 1.00 46.95 ? 269 GLN B OE1 1 
ATOM   5319 N NE2 . GLN B 2 269 ? 161.919 158.619 243.226 1.00 46.95 ? 269 GLN B NE2 1 
ATOM   5320 N N   . HIS B 2 270 ? 158.403 155.842 239.268 1.00 49.94 ? 270 HIS B N   1 
ATOM   5321 C CA  . HIS B 2 270 ? 157.522 154.695 239.084 1.00 49.94 ? 270 HIS B CA  1 
ATOM   5322 C C   . HIS B 2 270 ? 158.273 153.544 238.424 1.00 49.94 ? 270 HIS B C   1 
ATOM   5323 O O   . HIS B 2 270 ? 158.200 152.398 238.882 1.00 49.94 ? 270 HIS B O   1 
ATOM   5324 C CB  . HIS B 2 270 ? 156.300 155.115 238.262 1.00 49.94 ? 270 HIS B CB  1 
ATOM   5325 C CG  . HIS B 2 270 ? 155.282 154.033 238.061 1.00 49.94 ? 270 HIS B CG  1 
ATOM   5326 N ND1 . HIS B 2 270 ? 155.634 152.706 237.937 1.00 49.94 ? 270 HIS B ND1 1 
ATOM   5327 C CD2 . HIS B 2 270 ? 153.931 154.071 237.974 1.00 49.94 ? 270 HIS B CD2 1 
ATOM   5328 C CE1 . HIS B 2 270 ? 154.546 151.975 237.776 1.00 49.94 ? 270 HIS B CE1 1 
ATOM   5329 N NE2 . HIS B 2 270 ? 153.499 152.779 237.794 1.00 49.94 ? 270 HIS B NE2 1 
ATOM   5330 N N   . ASN B 2 271 ? 159.013 153.831 237.356 1.00 41.43 ? 271 ASN B N   1 
ATOM   5331 C CA  . ASN B 2 271 ? 159.875 152.850 236.711 1.00 41.43 ? 271 ASN B CA  1 
ATOM   5332 C C   . ASN B 2 271 ? 161.319 153.164 237.070 1.00 41.43 ? 271 ASN B C   1 
ATOM   5333 O O   . ASN B 2 271 ? 161.767 154.302 236.903 1.00 41.43 ? 271 ASN B O   1 
ATOM   5334 C CB  . ASN B 2 271 ? 159.699 152.865 235.193 1.00 41.43 ? 271 ASN B CB  1 
ATOM   5335 C CG  . ASN B 2 271 ? 158.256 153.008 234.775 1.00 41.43 ? 271 ASN B CG  1 
ATOM   5336 O OD1 . ASN B 2 271 ? 157.428 152.144 235.052 1.00 41.43 ? 271 ASN B OD1 1 
ATOM   5337 N ND2 . ASN B 2 271 ? 157.946 154.102 234.096 1.00 41.43 ? 271 ASN B ND2 1 
ATOM   5338 N N   . ASN B 2 272 ? 162.045 152.161 237.553 1.00 36.49 ? 272 ASN B N   1 
ATOM   5339 C CA  . ASN B 2 272 ? 163.395 152.381 238.068 1.00 36.49 ? 272 ASN B CA  1 
ATOM   5340 C C   . ASN B 2 272 ? 164.353 152.610 236.907 1.00 36.49 ? 272 ASN B C   1 
ATOM   5341 O O   . ASN B 2 272 ? 164.918 151.666 236.354 1.00 36.49 ? 272 ASN B O   1 
ATOM   5342 C CB  . ASN B 2 272 ? 163.837 151.198 238.919 1.00 36.49 ? 272 ASN B CB  1 
ATOM   5343 C CG  . ASN B 2 272 ? 165.056 151.512 239.759 1.00 36.49 ? 272 ASN B CG  1 
ATOM   5344 O OD1 . ASN B 2 272 ? 166.106 151.886 239.236 1.00 36.49 ? 272 ASN B OD1 1 
ATOM   5345 N ND2 . ASN B 2 272 ? 164.923 151.365 241.071 1.00 36.49 ? 272 ASN B ND2 1 
ATOM   5346 N N   . LEU B 2 273 ? 164.550 153.876 236.544 1.00 26.34 ? 273 LEU B N   1 
ATOM   5347 C CA  . LEU B 2 273 ? 165.497 154.250 235.502 1.00 26.34 ? 273 LEU B CA  1 
ATOM   5348 C C   . LEU B 2 273 ? 166.422 155.341 236.025 1.00 26.34 ? 273 LEU B C   1 
ATOM   5349 O O   . LEU B 2 273 ? 166.411 155.641 237.222 1.00 26.34 ? 273 LEU B O   1 
ATOM   5350 C CB  . LEU B 2 273 ? 164.763 154.715 234.245 1.00 26.34 ? 273 LEU B CB  1 
ATOM   5351 C CG  . LEU B 2 273 ? 163.834 153.698 233.585 1.00 26.34 ? 273 LEU B CG  1 
ATOM   5352 C CD1 . LEU B 2 273 ? 163.199 154.282 232.346 1.00 26.34 ? 273 LEU B CD1 1 
ATOM   5353 C CD2 . LEU B 2 273 ? 164.584 152.438 233.239 1.00 26.34 ? 273 LEU B CD2 1 
ATOM   5354 N N   . LEU B 2 274 ? 167.239 155.932 235.154 1.00 27.93 ? 274 LEU B N   1 
ATOM   5355 C CA  . LEU B 2 274 ? 168.112 157.014 235.593 1.00 27.93 ? 274 LEU B CA  1 
ATOM   5356 C C   . LEU B 2 274 ? 167.975 158.270 234.741 1.00 27.93 ? 274 LEU B C   1 
ATOM   5357 O O   . LEU B 2 274 ? 168.072 159.380 235.272 1.00 27.93 ? 274 LEU B O   1 
ATOM   5358 C CB  . LEU B 2 274 ? 169.575 156.568 235.615 1.00 27.93 ? 274 LEU B CB  1 
ATOM   5359 C CG  . LEU B 2 274 ? 170.066 155.700 236.779 1.00 27.93 ? 274 LEU B CG  1 
ATOM   5360 C CD1 . LEU B 2 274 ? 169.528 154.280 236.721 1.00 27.93 ? 274 LEU B CD1 1 
ATOM   5361 C CD2 . LEU B 2 274 ? 171.587 155.696 236.839 1.00 27.93 ? 274 LEU B CD2 1 
ATOM   5362 N N   . SER B 2 275 ? 167.759 158.129 233.436 1.00 20.81 ? 275 SER B N   1 
ATOM   5363 C CA  . SER B 2 275 ? 167.676 159.307 232.582 1.00 20.81 ? 275 SER B CA  1 
ATOM   5364 C C   . SER B 2 275 ? 167.010 158.953 231.261 1.00 20.81 ? 275 SER B C   1 
ATOM   5365 O O   . SER B 2 275 ? 166.883 157.783 230.895 1.00 20.81 ? 275 SER B O   1 
ATOM   5366 C CB  . SER B 2 275 ? 169.060 159.909 232.338 1.00 20.81 ? 275 SER B CB  1 
ATOM   5367 O OG  . SER B 2 275 ? 169.904 158.977 231.695 1.00 20.81 ? 275 SER B OG  1 
ATOM   5368 N N   . ILE B 2 276 ? 166.591 159.996 230.547 1.00 19.14 ? 276 ILE B N   1 
ATOM   5369 C CA  . ILE B 2 276 ? 166.040 159.911 229.199 1.00 19.14 ? 276 ILE B CA  1 
ATOM   5370 C C   . ILE B 2 276 ? 166.906 160.770 228.289 1.00 19.14 ? 276 ILE B C   1 
ATOM   5371 O O   . ILE B 2 276 ? 167.385 161.834 228.691 1.00 19.14 ? 276 ILE B O   1 
ATOM   5372 C CB  . ILE B 2 276 ? 164.562 160.367 229.136 1.00 19.14 ? 276 ILE B CB  1 
ATOM   5373 C CG1 . ILE B 2 276 ? 163.664 159.452 229.964 1.00 19.14 ? 276 ILE B CG1 1 
ATOM   5374 C CG2 . ILE B 2 276 ? 164.056 160.433 227.711 1.00 19.14 ? 276 ILE B CG2 1 
ATOM   5375 C CD1 . ILE B 2 276 ? 163.515 159.880 231.384 1.00 19.14 ? 276 ILE B CD1 1 
ATOM   5376 N N   . LEU B 2 277 ? 167.121 160.299 227.063 1.00 14.47 ? 277 LEU B N   1 
ATOM   5377 C CA  . LEU B 2 277 ? 167.887 161.029 226.067 1.00 14.47 ? 277 LEU B CA  1 
ATOM   5378 C C   . LEU B 2 277 ? 166.968 161.460 224.931 1.00 14.47 ? 277 LEU B C   1 
ATOM   5379 O O   . LEU B 2 277 ? 165.930 160.843 224.693 1.00 14.47 ? 277 LEU B O   1 
ATOM   5380 C CB  . LEU B 2 277 ? 169.035 160.178 225.526 1.00 14.47 ? 277 LEU B CB  1 
ATOM   5381 C CG  . LEU B 2 277 ? 170.217 159.950 226.469 1.00 14.47 ? 277 LEU B CG  1 
ATOM   5382 C CD1 . LEU B 2 277 ? 169.934 158.839 227.454 1.00 14.47 ? 277 LEU B CD1 1 
ATOM   5383 C CD2 . LEU B 2 277 ? 171.473 159.646 225.679 1.00 14.47 ? 277 LEU B CD2 1 
ATOM   5384 N N   . ARG B 2 278 ? 167.342 162.536 224.241 1.00 12.18 ? 278 ARG B N   1 
ATOM   5385 C CA  . ARG B 2 278 ? 166.509 163.051 223.160 1.00 12.18 ? 278 ARG B CA  1 
ATOM   5386 C C   . ARG B 2 278 ? 167.372 163.809 222.162 1.00 12.18 ? 278 ARG B C   1 
ATOM   5387 O O   . ARG B 2 278 ? 168.525 164.134 222.442 1.00 12.18 ? 278 ARG B O   1 
ATOM   5388 C CB  . ARG B 2 278 ? 165.402 163.952 223.702 1.00 12.18 ? 278 ARG B CB  1 
ATOM   5389 C CG  . ARG B 2 278 ? 165.871 164.938 224.743 1.00 12.18 ? 278 ARG B CG  1 
ATOM   5390 C CD  . ARG B 2 278 ? 164.701 165.719 225.285 1.00 12.18 ? 278 ARG B CD  1 
ATOM   5391 N NE  . ARG B 2 278 ? 163.923 166.314 224.208 1.00 12.18 ? 278 ARG B NE  1 
ATOM   5392 C CZ  . ARG B 2 278 ? 164.270 167.421 223.565 1.00 12.18 ? 278 ARG B CZ  1 
ATOM   5393 N NH1 . ARG B 2 278 ? 165.381 168.057 223.893 1.00 12.18 ? 278 ARG B NH1 1 
ATOM   5394 N NH2 . ARG B 2 278 ? 163.501 167.892 222.598 1.00 12.18 ? 278 ARG B NH2 1 
ATOM   5395 N N   . ALA B 2 279 ? 166.819 164.059 220.972 1.00 6.90  ? 279 ALA B N   1 
ATOM   5396 C CA  . ALA B 2 279 ? 167.615 164.652 219.901 1.00 6.90  ? 279 ALA B CA  1 
ATOM   5397 C C   . ALA B 2 279 ? 166.839 165.671 219.064 1.00 6.90  ? 279 ALA B C   1 
ATOM   5398 O O   . ALA B 2 279 ? 166.940 165.669 217.834 1.00 6.90  ? 279 ALA B O   1 
ATOM   5399 C CB  . ALA B 2 279 ? 168.186 163.567 218.994 1.00 6.90  ? 279 ALA B CB  1 
ATOM   5400 N N   . HIS B 2 280 ? 166.065 166.566 219.683 1.00 10.15 ? 280 HIS B N   1 
ATOM   5401 C CA  . HIS B 2 280 ? 165.498 167.700 218.944 1.00 10.15 ? 280 HIS B CA  1 
ATOM   5402 C C   . HIS B 2 280 ? 166.261 169.007 219.116 1.00 10.15 ? 280 HIS B C   1 
ATOM   5403 O O   . HIS B 2 280 ? 166.729 169.585 218.133 1.00 10.15 ? 280 HIS B O   1 
ATOM   5404 C CB  . HIS B 2 280 ? 164.029 167.968 219.303 1.00 10.15 ? 280 HIS B CB  1 
ATOM   5405 C CG  . HIS B 2 280 ? 163.050 167.038 218.667 1.00 10.15 ? 280 HIS B CG  1 
ATOM   5406 N ND1 . HIS B 2 280 ? 161.720 167.016 219.024 1.00 10.15 ? 280 HIS B ND1 1 
ATOM   5407 C CD2 . HIS B 2 280 ? 163.171 166.191 217.620 1.00 10.15 ? 280 HIS B CD2 1 
ATOM   5408 C CE1 . HIS B 2 280 ? 161.076 166.150 218.265 1.00 10.15 ? 280 HIS B CE1 1 
ATOM   5409 N NE2 . HIS B 2 280 ? 161.934 165.637 217.402 1.00 10.15 ? 280 HIS B NE2 1 
ATOM   5410 N N   . GLU B 2 281 ? 166.367 169.506 220.338 1.00 24.13 ? 281 GLU B N   1 
ATOM   5411 C CA  . GLU B 2 281 ? 166.783 170.889 220.528 1.00 24.13 ? 281 GLU B CA  1 
ATOM   5412 C C   . GLU B 2 281 ? 168.262 171.045 220.207 1.00 24.13 ? 281 GLU B C   1 
ATOM   5413 O O   . GLU B 2 281 ? 169.120 170.481 220.894 1.00 24.13 ? 281 GLU B O   1 
ATOM   5414 C CB  . GLU B 2 281 ? 166.484 171.342 221.954 1.00 24.13 ? 281 GLU B CB  1 
ATOM   5415 C CG  . GLU B 2 281 ? 165.006 171.533 222.241 1.00 24.13 ? 281 GLU B CG  1 
ATOM   5416 C CD  . GLU B 2 281 ? 164.766 172.413 223.449 1.00 24.13 ? 281 GLU B CD  1 
ATOM   5417 O OE1 . GLU B 2 281 ? 165.752 172.782 224.120 1.00 24.13 ? 281 GLU B OE1 1 
ATOM   5418 O OE2 . GLU B 2 281 ? 163.594 172.741 223.725 1.00 24.13 ? 281 GLU B OE2 1 
ATOM   5419 N N   . ALA B 2 282 ? 168.554 171.819 219.165 1.00 19.97 ? 282 ALA B N   1 
ATOM   5420 C CA  . ALA B 2 282 ? 169.932 172.062 218.768 1.00 19.97 ? 282 ALA B CA  1 
ATOM   5421 C C   . ALA B 2 282 ? 170.692 172.765 219.882 1.00 19.97 ? 282 ALA B C   1 
ATOM   5422 O O   . ALA B 2 282 ? 170.214 173.747 220.455 1.00 19.97 ? 282 ALA B O   1 
ATOM   5423 C CB  . ALA B 2 282 ? 169.965 172.899 217.492 1.00 19.97 ? 282 ALA B CB  1 
ATOM   5424 N N   . GLN B 2 283 ? 171.884 172.265 220.183 1.00 24.64 ? 283 GLN B N   1 
ATOM   5425 C CA  . GLN B 2 283 ? 172.720 172.807 221.243 1.00 24.64 ? 283 GLN B CA  1 
ATOM   5426 C C   . GLN B 2 283 ? 173.985 173.389 220.635 1.00 24.64 ? 283 GLN B C   1 
ATOM   5427 O O   . GLN B 2 283 ? 174.675 172.711 219.869 1.00 24.64 ? 283 GLN B O   1 
ATOM   5428 C CB  . GLN B 2 283 ? 173.076 171.730 222.266 1.00 24.64 ? 283 GLN B CB  1 
ATOM   5429 C CG  . GLN B 2 283 ? 171.905 170.870 222.677 1.00 24.64 ? 283 GLN B CG  1 
ATOM   5430 C CD  . GLN B 2 283 ? 170.838 171.656 223.399 1.00 24.64 ? 283 GLN B CD  1 
ATOM   5431 O OE1 . GLN B 2 283 ? 171.126 172.401 224.334 1.00 24.64 ? 283 GLN B OE1 1 
ATOM   5432 N NE2 . GLN B 2 283 ? 169.595 171.490 222.974 1.00 24.64 ? 283 GLN B NE2 1 
ATOM   5433 N N   . ASP B 2 284 ? 174.290 174.642 220.984 1.00 26.83 ? 284 ASP B N   1 
ATOM   5434 C CA  . ASP B 2 284 ? 175.497 175.272 220.462 1.00 26.83 ? 284 ASP B CA  1 
ATOM   5435 C C   . ASP B 2 284 ? 176.750 174.559 220.946 1.00 26.83 ? 284 ASP B C   1 
ATOM   5436 O O   . ASP B 2 284 ? 177.760 174.531 220.237 1.00 26.83 ? 284 ASP B O   1 
ATOM   5437 C CB  . ASP B 2 284 ? 175.538 176.746 220.855 1.00 26.83 ? 284 ASP B CB  1 
ATOM   5438 C CG  . ASP B 2 284 ? 176.502 177.547 220.003 1.00 26.83 ? 284 ASP B CG  1 
ATOM   5439 O OD1 . ASP B 2 284 ? 176.035 178.334 219.153 1.00 26.83 ? 284 ASP B OD1 1 
ATOM   5440 O OD2 . ASP B 2 284 ? 177.727 177.394 220.184 1.00 26.83 ? 284 ASP B OD2 1 
ATOM   5441 N N   . ALA B 2 285 ? 176.710 173.985 222.145 1.00 23.27 ? 285 ALA B N   1 
ATOM   5442 C CA  . ALA B 2 285 ? 177.791 173.132 222.614 1.00 23.27 ? 285 ALA B CA  1 
ATOM   5443 C C   . ALA B 2 285 ? 177.674 171.705 222.103 1.00 23.27 ? 285 ALA B C   1 
ATOM   5444 O O   . ALA B 2 285 ? 178.638 170.942 222.221 1.00 23.27 ? 285 ALA B O   1 
ATOM   5445 C CB  . ALA B 2 285 ? 177.838 173.123 224.144 1.00 23.27 ? 285 ALA B CB  1 
ATOM   5446 N N   . GLY B 2 286 ? 176.523 171.330 221.542 1.00 17.06 ? 286 GLY B N   1 
ATOM   5447 C CA  . GLY B 2 286 ? 176.290 170.018 220.996 1.00 17.06 ? 286 GLY B CA  1 
ATOM   5448 C C   . GLY B 2 286 ? 175.492 169.100 221.898 1.00 17.06 ? 286 GLY B C   1 
ATOM   5449 O O   . GLY B 2 286 ? 174.842 168.175 221.405 1.00 17.06 ? 286 GLY B O   1 
ATOM   5450 N N   . TYR B 2 287 ? 175.522 169.338 223.205 1.00 22.12 ? 287 TYR B N   1 
ATOM   5451 C CA  . TYR B 2 287 ? 174.780 168.537 224.162 1.00 22.12 ? 287 TYR B CA  1 
ATOM   5452 C C   . TYR B 2 287 ? 174.250 169.452 225.252 1.00 22.12 ? 287 TYR B C   1 
ATOM   5453 O O   . TYR B 2 287 ? 174.657 170.609 225.375 1.00 22.12 ? 287 TYR B O   1 
ATOM   5454 C CB  . TYR B 2 287 ? 175.648 167.434 224.776 1.00 22.12 ? 287 TYR B CB  1 
ATOM   5455 C CG  . TYR B 2 287 ? 176.654 167.940 225.785 1.00 22.12 ? 287 TYR B CG  1 
ATOM   5456 C CD1 . TYR B 2 287 ? 177.938 168.290 225.397 1.00 22.12 ? 287 TYR B CD1 1 
ATOM   5457 C CD2 . TYR B 2 287 ? 176.323 168.066 227.127 1.00 22.12 ? 287 TYR B CD2 1 
ATOM   5458 C CE1 . TYR B 2 287 ? 178.862 168.754 226.315 1.00 22.12 ? 287 TYR B CE1 1 
ATOM   5459 C CE2 . TYR B 2 287 ? 177.238 168.531 228.050 1.00 22.12 ? 287 TYR B CE2 1 
ATOM   5460 C CZ  . TYR B 2 287 ? 178.505 168.872 227.639 1.00 22.12 ? 287 TYR B CZ  1 
ATOM   5461 O OH  . TYR B 2 287 ? 179.418 169.331 228.559 1.00 22.12 ? 287 TYR B OH  1 
ATOM   5462 N N   . ARG B 2 288 ? 173.331 168.922 226.051 1.00 28.39 ? 288 ARG B N   1 
ATOM   5463 C CA  . ARG B 2 288 ? 172.878 169.641 227.235 1.00 28.39 ? 288 ARG B CA  1 
ATOM   5464 C C   . ARG B 2 288 ? 172.381 168.658 228.279 1.00 28.39 ? 288 ARG B C   1 
ATOM   5465 O O   . ARG B 2 288 ? 171.527 167.816 227.984 1.00 28.39 ? 288 ARG B O   1 
ATOM   5466 C CB  . ARG B 2 288 ? 171.774 170.645 226.901 1.00 28.39 ? 288 ARG B CB  1 
ATOM   5467 C CG  . ARG B 2 288 ? 171.385 171.503 228.089 1.00 28.39 ? 288 ARG B CG  1 
ATOM   5468 C CD  . ARG B 2 288 ? 170.617 172.743 227.673 1.00 28.39 ? 288 ARG B CD  1 
ATOM   5469 N NE  . ARG B 2 288 ? 169.933 173.351 228.810 1.00 28.39 ? 288 ARG B NE  1 
ATOM   5470 C CZ  . ARG B 2 288 ? 168.968 174.257 228.705 1.00 28.39 ? 288 ARG B CZ  1 
ATOM   5471 N NH1 . ARG B 2 288 ? 168.569 174.668 227.510 1.00 28.39 ? 288 ARG B NH1 1 
ATOM   5472 N NH2 . ARG B 2 288 ? 168.402 174.752 229.795 1.00 28.39 ? 288 ARG B NH2 1 
ATOM   5473 N N   . MET B 2 289 ? 172.914 168.773 229.491 1.00 36.88 ? 289 MET B N   1 
ATOM   5474 C CA  . MET B 2 289 ? 172.449 168.002 230.635 1.00 36.88 ? 289 MET B CA  1 
ATOM   5475 C C   . MET B 2 289 ? 171.506 168.878 231.448 1.00 36.88 ? 289 MET B C   1 
ATOM   5476 O O   . MET B 2 289 ? 171.890 169.966 231.890 1.00 36.88 ? 289 MET B O   1 
ATOM   5477 C CB  . MET B 2 289 ? 173.618 167.524 231.494 1.00 36.88 ? 289 MET B CB  1 
ATOM   5478 C CG  . MET B 2 289 ? 174.736 166.862 230.712 1.00 36.88 ? 289 MET B CG  1 
ATOM   5479 S SD  . MET B 2 289 ? 175.681 165.712 231.728 1.00 36.88 ? 289 MET B SD  1 
ATOM   5480 C CE  . MET B 2 289 ? 176.630 164.849 230.480 1.00 36.88 ? 289 MET B CE  1 
ATOM   5481 N N   . TYR B 2 290 ? 170.281 168.403 231.647 1.00 43.84 ? 290 TYR B N   1 
ATOM   5482 C CA  . TYR B 2 290 ? 169.236 169.213 232.257 1.00 43.84 ? 290 TYR B CA  1 
ATOM   5483 C C   . TYR B 2 290 ? 169.409 169.228 233.775 1.00 43.84 ? 290 TYR B C   1 
ATOM   5484 O O   . TYR B 2 290 ? 170.451 168.841 234.310 1.00 43.84 ? 290 TYR B O   1 
ATOM   5485 C CB  . TYR B 2 290 ? 167.864 168.707 231.826 1.00 43.84 ? 290 TYR B CB  1 
ATOM   5486 C CG  . TYR B 2 290 ? 167.447 169.216 230.467 1.00 43.84 ? 290 TYR B CG  1 
ATOM   5487 C CD1 . TYR B 2 290 ? 168.320 169.953 229.684 1.00 43.84 ? 290 TYR B CD1 1 
ATOM   5488 C CD2 . TYR B 2 290 ? 166.177 168.976 229.975 1.00 43.84 ? 290 TYR B CD2 1 
ATOM   5489 C CE1 . TYR B 2 290 ? 167.943 170.425 228.447 1.00 43.84 ? 290 TYR B CE1 1 
ATOM   5490 C CE2 . TYR B 2 290 ? 165.790 169.449 228.739 1.00 43.84 ? 290 TYR B CE2 1 
ATOM   5491 C CZ  . TYR B 2 290 ? 166.677 170.172 227.981 1.00 43.84 ? 290 TYR B CZ  1 
ATOM   5492 O OH  . TYR B 2 290 ? 166.296 170.644 226.749 1.00 43.84 ? 290 TYR B OH  1 
ATOM   5493 N N   . ARG B 2 291 ? 168.383 169.702 234.482 1.00 65.98 ? 291 ARG B N   1 
ATOM   5494 C CA  . ARG B 2 291 ? 168.482 169.902 235.922 1.00 65.98 ? 291 ARG B CA  1 
ATOM   5495 C C   . ARG B 2 291 ? 168.810 168.598 236.635 1.00 65.98 ? 291 ARG B C   1 
ATOM   5496 O O   . ARG B 2 291 ? 168.288 167.533 236.296 1.00 65.98 ? 291 ARG B O   1 
ATOM   5497 C CB  . ARG B 2 291 ? 167.178 170.482 236.468 1.00 65.98 ? 291 ARG B CB  1 
ATOM   5498 C CG  . ARG B 2 291 ? 167.346 171.307 237.736 1.00 65.98 ? 291 ARG B CG  1 
ATOM   5499 C CD  . ARG B 2 291 ? 166.004 171.551 238.411 1.00 65.98 ? 291 ARG B CD  1 
ATOM   5500 N NE  . ARG B 2 291 ? 165.990 172.791 239.181 1.00 65.98 ? 291 ARG B NE  1 
ATOM   5501 C CZ  . ARG B 2 291 ? 165.584 173.963 238.703 1.00 65.98 ? 291 ARG B CZ  1 
ATOM   5502 N NH1 . ARG B 2 291 ? 165.160 174.058 237.451 1.00 65.98 ? 291 ARG B NH1 1 
ATOM   5503 N NH2 . ARG B 2 291 ? 165.603 175.041 239.473 1.00 65.98 ? 291 ARG B NH2 1 
ATOM   5504 N N   . LYS B 2 292 ? 169.685 168.694 237.631 1.00 68.23 ? 292 LYS B N   1 
ATOM   5505 C CA  . LYS B 2 292 ? 170.176 167.515 238.327 1.00 68.23 ? 292 LYS B CA  1 
ATOM   5506 C C   . LYS B 2 292 ? 169.053 166.836 239.101 1.00 68.23 ? 292 LYS B C   1 
ATOM   5507 O O   . LYS B 2 292 ? 168.251 167.493 239.769 1.00 68.23 ? 292 LYS B O   1 
ATOM   5508 C CB  . LYS B 2 292 ? 171.304 167.904 239.280 1.00 68.23 ? 292 LYS B CB  1 
ATOM   5509 C CG  . LYS B 2 292 ? 172.064 166.731 239.856 1.00 68.23 ? 292 LYS B CG  1 
ATOM   5510 C CD  . LYS B 2 292 ? 172.818 166.007 238.763 1.00 68.23 ? 292 LYS B CD  1 
ATOM   5511 C CE  . LYS B 2 292 ? 173.833 166.927 238.107 1.00 68.23 ? 292 LYS B CE  1 
ATOM   5512 N NZ  . LYS B 2 292 ? 174.904 167.336 239.054 1.00 68.23 ? 292 LYS B NZ  1 
ATOM   5513 N N   . SER B 2 293 ? 169.002 165.511 239.011 1.00 67.60 ? 293 SER B N   1 
ATOM   5514 C CA  . SER B 2 293 ? 168.019 164.738 239.757 1.00 67.60 ? 293 SER B CA  1 
ATOM   5515 C C   . SER B 2 293 ? 168.537 164.511 241.171 1.00 67.60 ? 293 SER B C   1 
ATOM   5516 O O   . SER B 2 293 ? 169.649 164.005 241.357 1.00 67.60 ? 293 SER B O   1 
ATOM   5517 C CB  . SER B 2 293 ? 167.740 163.408 239.061 1.00 67.60 ? 293 SER B CB  1 
ATOM   5518 O OG  . SER B 2 293 ? 166.839 162.616 239.815 1.00 67.60 ? 293 SER B OG  1 
ATOM   5519 N N   . GLN B 2 294 ? 167.735 164.889 242.167 1.00 79.96 ? 294 GLN B N   1 
ATOM   5520 C CA  . GLN B 2 294 ? 168.187 164.794 243.550 1.00 79.96 ? 294 GLN B CA  1 
ATOM   5521 C C   . GLN B 2 294 ? 168.157 163.360 244.063 1.00 79.96 ? 294 GLN B C   1 
ATOM   5522 O O   . GLN B 2 294 ? 168.782 163.059 245.085 1.00 79.96 ? 294 GLN B O   1 
ATOM   5523 C CB  . GLN B 2 294 ? 167.341 165.707 244.439 1.00 79.96 ? 294 GLN B CB  1 
ATOM   5524 C CG  . GLN B 2 294 ? 165.863 165.349 244.507 1.00 79.96 ? 294 GLN B CG  1 
ATOM   5525 C CD  . GLN B 2 294 ? 165.565 164.271 245.529 1.00 79.96 ? 294 GLN B CD  1 
ATOM   5526 O OE1 . GLN B 2 294 ? 166.259 164.148 246.538 1.00 79.96 ? 294 GLN B OE1 1 
ATOM   5527 N NE2 . GLN B 2 294 ? 164.524 163.488 245.276 1.00 79.96 ? 294 GLN B NE2 1 
ATOM   5528 N N   . THR B 2 295 ? 167.433 162.470 243.381 1.00 77.87 ? 295 THR B N   1 
ATOM   5529 C CA  . THR B 2 295 ? 167.330 161.092 243.854 1.00 77.87 ? 295 THR B CA  1 
ATOM   5530 C C   . THR B 2 295 ? 168.673 160.372 243.784 1.00 77.87 ? 295 THR B C   1 
ATOM   5531 O O   . THR B 2 295 ? 169.112 159.770 244.771 1.00 77.87 ? 295 THR B O   1 
ATOM   5532 C CB  . THR B 2 295 ? 166.277 160.334 243.045 1.00 77.87 ? 295 THR B CB  1 
ATOM   5533 O OG1 . THR B 2 295 ? 166.569 160.451 241.647 1.00 77.87 ? 295 THR B OG1 1 
ATOM   5534 C CG2 . THR B 2 295 ? 164.890 160.891 243.316 1.00 77.87 ? 295 THR B CG2 1 
ATOM   5535 N N   . THR B 2 296 ? 169.340 160.420 242.630 1.00 69.03 ? 296 THR B N   1 
ATOM   5536 C CA  . THR B 2 296 ? 170.583 159.687 242.421 1.00 69.03 ? 296 THR B CA  1 
ATOM   5537 C C   . THR B 2 296 ? 171.774 160.607 242.191 1.00 69.03 ? 296 THR B C   1 
ATOM   5538 O O   . THR B 2 296 ? 172.760 160.539 242.931 1.00 69.03 ? 296 THR B O   1 
ATOM   5539 C CB  . THR B 2 296 ? 170.433 158.722 241.238 1.00 69.03 ? 296 THR B CB  1 
ATOM   5540 O OG1 . THR B 2 296 ? 170.272 159.474 240.028 1.00 69.03 ? 296 THR B OG1 1 
ATOM   5541 C CG2 . THR B 2 296 ? 169.228 157.813 241.435 1.00 69.03 ? 296 THR B CG2 1 
ATOM   5542 N N   . GLY B 2 297 ? 171.712 161.472 241.183 1.00 62.54 ? 297 GLY B N   1 
ATOM   5543 C CA  . GLY B 2 297 ? 172.843 162.318 240.859 1.00 62.54 ? 297 GLY B CA  1 
ATOM   5544 C C   . GLY B 2 297 ? 173.152 162.400 239.378 1.00 62.54 ? 297 GLY B C   1 
ATOM   5545 O O   . GLY B 2 297 ? 174.058 163.134 238.971 1.00 62.54 ? 297 GLY B O   1 
ATOM   5546 N N   . PHE B 2 298 ? 172.426 161.641 238.560 1.00 56.16 ? 298 PHE B N   1 
ATOM   5547 C CA  . PHE B 2 298 ? 172.579 161.886 237.133 1.00 56.16 ? 298 PHE B CA  1 
ATOM   5548 C C   . PHE B 2 298 ? 171.474 162.807 236.640 1.00 56.16 ? 298 PHE B C   1 
ATOM   5549 O O   . PHE B 2 298 ? 170.358 162.768 237.168 1.00 56.16 ? 298 PHE B O   1 
ATOM   5550 C CB  . PHE B 2 298 ? 172.530 160.582 236.335 1.00 56.16 ? 298 PHE B CB  1 
ATOM   5551 C CG  . PHE B 2 298 ? 173.693 159.667 236.584 1.00 56.16 ? 298 PHE B CG  1 
ATOM   5552 C CD1 . PHE B 2 298 ? 174.904 159.879 235.950 1.00 56.16 ? 298 PHE B CD1 1 
ATOM   5553 C CD2 . PHE B 2 298 ? 173.570 158.585 237.439 1.00 56.16 ? 298 PHE B CD2 1 
ATOM   5554 C CE1 . PHE B 2 298 ? 175.976 159.034 236.172 1.00 56.16 ? 298 PHE B CE1 1 
ATOM   5555 C CE2 . PHE B 2 298 ? 174.637 157.736 237.665 1.00 56.16 ? 298 PHE B CE2 1 
ATOM   5556 C CZ  . PHE B 2 298 ? 175.841 157.961 237.031 1.00 56.16 ? 298 PHE B CZ  1 
ATOM   5557 N N   . PRO B 2 299 ? 171.747 163.650 235.646 1.00 45.69 ? 299 PRO B N   1 
ATOM   5558 C CA  . PRO B 2 299 ? 170.684 164.499 235.096 1.00 45.69 ? 299 PRO B CA  1 
ATOM   5559 C C   . PRO B 2 299 ? 169.558 163.653 234.519 1.00 45.69 ? 299 PRO B C   1 
ATOM   5560 O O   . PRO B 2 299 ? 169.787 162.585 233.950 1.00 45.69 ? 299 PRO B O   1 
ATOM   5561 C CB  . PRO B 2 299 ? 171.397 165.316 234.012 1.00 45.69 ? 299 PRO B CB  1 
ATOM   5562 C CG  . PRO B 2 299 ? 172.692 164.618 233.766 1.00 45.69 ? 299 PRO B CG  1 
ATOM   5563 C CD  . PRO B 2 299 ? 173.055 163.918 235.030 1.00 45.69 ? 299 PRO B CD  1 
ATOM   5564 N N   . SER B 2 300 ? 168.327 164.137 234.687 1.00 35.58 ? 300 SER B N   1 
ATOM   5565 C CA  . SER B 2 300 ? 167.168 163.345 234.290 1.00 35.58 ? 300 SER B CA  1 
ATOM   5566 C C   . SER B 2 300 ? 166.994 163.319 232.778 1.00 35.58 ? 300 SER B C   1 
ATOM   5567 O O   . SER B 2 300 ? 166.596 162.296 232.213 1.00 35.58 ? 300 SER B O   1 
ATOM   5568 C CB  . SER B 2 300 ? 165.910 163.884 234.963 1.00 35.58 ? 300 SER B CB  1 
ATOM   5569 O OG  . SER B 2 300 ? 165.859 163.492 236.322 1.00 35.58 ? 300 SER B OG  1 
ATOM   5570 N N   . LEU B 2 301 ? 167.274 164.430 232.106 1.00 26.94 ? 301 LEU B N   1 
ATOM   5571 C CA  . LEU B 2 301 ? 167.078 164.535 230.668 1.00 26.94 ? 301 LEU B CA  1 
ATOM   5572 C C   . LEU B 2 301 ? 168.363 165.028 230.026 1.00 26.94 ? 301 LEU B C   1 
ATOM   5573 O O   . LEU B 2 301 ? 168.966 165.993 230.504 1.00 26.94 ? 301 LEU B O   1 
ATOM   5574 C CB  . LEU B 2 301 ? 165.923 165.479 230.341 1.00 26.94 ? 301 LEU B CB  1 
ATOM   5575 C CG  . LEU B 2 301 ? 165.333 165.389 228.940 1.00 26.94 ? 301 LEU B CG  1 
ATOM   5576 C CD1 . LEU B 2 301 ? 164.901 163.978 228.650 1.00 26.94 ? 301 LEU B CD1 1 
ATOM   5577 C CD2 . LEU B 2 301 ? 164.154 166.315 228.829 1.00 26.94 ? 301 LEU B CD2 1 
ATOM   5578 N N   . ILE B 2 302 ? 168.783 164.365 228.953 1.00 18.56 ? 302 ILE B N   1 
ATOM   5579 C CA  . ILE B 2 302 ? 169.977 164.740 228.207 1.00 18.56 ? 302 ILE B CA  1 
ATOM   5580 C C   . ILE B 2 302 ? 169.585 164.956 226.754 1.00 18.56 ? 302 ILE B C   1 
ATOM   5581 O O   . ILE B 2 302 ? 168.871 164.134 226.169 1.00 18.56 ? 302 ILE B O   1 
ATOM   5582 C CB  . ILE B 2 302 ? 171.081 163.676 228.324 1.00 18.56 ? 302 ILE B CB  1 
ATOM   5583 C CG1 . ILE B 2 302 ? 171.331 163.331 229.789 1.00 18.56 ? 302 ILE B CG1 1 
ATOM   5584 C CG2 . ILE B 2 302 ? 172.356 164.171 227.682 1.00 18.56 ? 302 ILE B CG2 1 
ATOM   5585 C CD1 . ILE B 2 302 ? 172.163 162.092 229.986 1.00 18.56 ? 302 ILE B CD1 1 
ATOM   5586 N N   . THR B 2 303 ? 170.038 166.066 226.182 1.00 16.95 ? 303 THR B N   1 
ATOM   5587 C CA  . THR B 2 303 ? 169.789 166.390 224.787 1.00 16.95 ? 303 THR B CA  1 
ATOM   5588 C C   . THR B 2 303 ? 171.083 166.259 224.005 1.00 16.95 ? 303 THR B C   1 
ATOM   5589 O O   . THR B 2 303 ? 172.096 166.862 224.374 1.00 16.95 ? 303 THR B O   1 
ATOM   5590 C CB  . THR B 2 303 ? 169.232 167.804 224.637 1.00 16.95 ? 303 THR B CB  1 
ATOM   5591 O OG1 . THR B 2 303 ? 167.996 167.910 225.350 1.00 16.95 ? 303 THR B OG1 1 
ATOM   5592 C CG2 . THR B 2 303 ? 169.003 168.132 223.179 1.00 16.95 ? 303 THR B CG2 1 
ATOM   5593 N N   . ILE B 2 304 ? 171.043 165.470 222.934 1.00 10.21 ? 304 ILE B N   1 
ATOM   5594 C CA  . ILE B 2 304 ? 172.173 165.263 222.040 1.00 10.21 ? 304 ILE B CA  1 
ATOM   5595 C C   . ILE B 2 304 ? 171.883 166.005 220.746 1.00 10.21 ? 304 ILE B C   1 
ATOM   5596 O O   . ILE B 2 304 ? 170.729 166.292 220.419 1.00 10.21 ? 304 ILE B O   1 
ATOM   5597 C CB  . ILE B 2 304 ? 172.413 163.763 221.769 1.00 10.21 ? 304 ILE B CB  1 
ATOM   5598 C CG1 . ILE B 2 304 ? 172.328 162.961 223.059 1.00 10.21 ? 304 ILE B CG1 1 
ATOM   5599 C CG2 . ILE B 2 304 ? 173.777 163.540 221.176 1.00 10.21 ? 304 ILE B CG2 1 
ATOM   5600 C CD1 . ILE B 2 304 ? 173.477 163.200 223.987 1.00 10.21 ? 304 ILE B CD1 1 
ATOM   5601 N N   . PHE B 2 305 ? 172.941 166.331 220.012 1.00 11.50 ? 305 PHE B N   1 
ATOM   5602 C CA  . PHE B 2 305 ? 172.793 166.914 218.683 1.00 11.50 ? 305 PHE B CA  1 
ATOM   5603 C C   . PHE B 2 305 ? 174.109 166.723 217.953 1.00 11.50 ? 305 PHE B C   1 
ATOM   5604 O O   . PHE B 2 305 ? 175.131 167.266 218.381 1.00 11.50 ? 305 PHE B O   1 
ATOM   5605 C CB  . PHE B 2 305 ? 172.428 168.384 218.768 1.00 11.50 ? 305 PHE B CB  1 
ATOM   5606 C CG  . PHE B 2 305 ? 171.880 168.940 217.497 1.00 11.50 ? 305 PHE B CG  1 
ATOM   5607 C CD1 . PHE B 2 305 ? 172.641 169.779 216.712 1.00 11.50 ? 305 PHE B CD1 1 
ATOM   5608 C CD2 . PHE B 2 305 ? 170.603 168.627 217.089 1.00 11.50 ? 305 PHE B CD2 1 
ATOM   5609 C CE1 . PHE B 2 305 ? 172.137 170.294 215.541 1.00 11.50 ? 305 PHE B CE1 1 
ATOM   5610 C CE2 . PHE B 2 305 ? 170.094 169.136 215.918 1.00 11.50 ? 305 PHE B CE2 1 
ATOM   5611 C CZ  . PHE B 2 305 ? 170.860 169.972 215.144 1.00 11.50 ? 305 PHE B CZ  1 
ATOM   5612 N N   . SER B 2 306 ? 174.093 165.962 216.864 1.00 11.32 ? 306 SER B N   1 
ATOM   5613 C CA  . SER B 2 306 ? 175.313 165.579 216.168 1.00 11.32 ? 306 SER B CA  1 
ATOM   5614 C C   . SER B 2 306 ? 175.237 165.955 214.697 1.00 11.32 ? 306 SER B C   1 
ATOM   5615 O O   . SER B 2 306 ? 175.503 165.147 213.807 1.00 11.32 ? 306 SER B O   1 
ATOM   5616 C CB  . SER B 2 306 ? 175.586 164.095 216.339 1.00 11.32 ? 306 SER B CB  1 
ATOM   5617 O OG  . SER B 2 306 ? 174.483 163.341 215.899 1.00 11.32 ? 306 SER B OG  1 
ATOM   5618 N N   . ALA B 2 307 ? 174.862 167.205 214.425 1.00 12.12 ? 307 ALA B N   1 
ATOM   5619 C CA  . ALA B 2 307 ? 174.871 167.770 213.077 1.00 12.12 ? 307 ALA B CA  1 
ATOM   5620 C C   . ALA B 2 307 ? 175.521 169.146 213.124 1.00 12.12 ? 307 ALA B C   1 
ATOM   5621 O O   . ALA B 2 307 ? 174.842 170.153 213.357 1.00 12.12 ? 307 ALA B O   1 
ATOM   5622 C CB  . ALA B 2 307 ? 173.459 167.853 212.508 1.00 12.12 ? 307 ALA B CB  1 
ATOM   5623 N N   . PRO B 2 308 ? 176.833 169.230 212.912 1.00 13.62 ? 308 PRO B N   1 
ATOM   5624 C CA  . PRO B 2 308 ? 177.510 170.530 212.977 1.00 13.62 ? 308 PRO B CA  1 
ATOM   5625 C C   . PRO B 2 308 ? 177.091 171.449 211.842 1.00 13.62 ? 308 PRO B C   1 
ATOM   5626 O O   . PRO B 2 308 ? 176.778 171.002 210.737 1.00 13.62 ? 308 PRO B O   1 
ATOM   5627 C CB  . PRO B 2 308 ? 178.990 170.159 212.865 1.00 13.62 ? 308 PRO B CB  1 
ATOM   5628 C CG  . PRO B 2 308 ? 178.985 168.890 212.111 1.00 13.62 ? 308 PRO B CG  1 
ATOM   5629 C CD  . PRO B 2 308 ? 177.761 168.149 212.549 1.00 13.62 ? 308 PRO B CD  1 
ATOM   5630 N N   . ASN B 2 309 ? 177.116 172.753 212.121 1.00 23.86 ? 309 ASN B N   1 
ATOM   5631 C CA  . ASN B 2 309 ? 176.644 173.771 211.181 1.00 23.86 ? 309 ASN B CA  1 
ATOM   5632 C C   . ASN B 2 309 ? 175.250 173.439 210.666 1.00 23.86 ? 309 ASN B C   1 
ATOM   5633 O O   . ASN B 2 309 ? 175.021 173.312 209.463 1.00 23.86 ? 309 ASN B O   1 
ATOM   5634 C CB  . ASN B 2 309 ? 177.613 173.957 210.011 1.00 23.86 ? 309 ASN B CB  1 
ATOM   5635 C CG  . ASN B 2 309 ? 178.741 174.916 210.326 1.00 23.86 ? 309 ASN B CG  1 
ATOM   5636 O OD1 . ASN B 2 309 ? 178.534 175.940 210.967 1.00 23.86 ? 309 ASN B OD1 1 
ATOM   5637 N ND2 . ASN B 2 309 ? 179.936 174.603 209.845 1.00 23.86 ? 309 ASN B ND2 1 
ATOM   5638 N N   . TYR B 2 310 ? 174.311 173.285 211.593 1.00 25.61 ? 310 TYR B N   1 
ATOM   5639 C CA  . TYR B 2 310 ? 172.937 173.007 211.202 1.00 25.61 ? 310 TYR B CA  1 
ATOM   5640 C C   . TYR B 2 310 ? 172.435 174.119 210.294 1.00 25.61 ? 310 TYR B C   1 
ATOM   5641 O O   . TYR B 2 310 ? 172.676 175.300 210.554 1.00 25.61 ? 310 TYR B O   1 
ATOM   5642 C CB  . TYR B 2 310 ? 172.049 172.869 212.438 1.00 25.61 ? 310 TYR B CB  1 
ATOM   5643 C CG  . TYR B 2 310 ? 170.616 172.516 212.124 1.00 25.61 ? 310 TYR B CG  1 
ATOM   5644 C CD1 . TYR B 2 310 ? 170.304 171.669 211.076 1.00 25.61 ? 310 TYR B CD1 1 
ATOM   5645 C CD2 . TYR B 2 310 ? 169.575 173.030 212.880 1.00 25.61 ? 310 TYR B CD2 1 
ATOM   5646 C CE1 . TYR B 2 310 ? 168.999 171.352 210.785 1.00 25.61 ? 310 TYR B CE1 1 
ATOM   5647 C CE2 . TYR B 2 310 ? 168.266 172.716 212.597 1.00 25.61 ? 310 TYR B CE2 1 
ATOM   5648 C CZ  . TYR B 2 310 ? 167.985 171.876 211.550 1.00 25.61 ? 310 TYR B CZ  1 
ATOM   5649 O OH  . TYR B 2 310 ? 166.680 171.561 211.265 1.00 25.61 ? 310 TYR B OH  1 
ATOM   5650 N N   . LEU B 2 311 ? 171.790 173.735 209.193 1.00 27.63 ? 311 LEU B N   1 
ATOM   5651 C CA  . LEU B 2 311 ? 171.320 174.673 208.171 1.00 27.63 ? 311 LEU B CA  1 
ATOM   5652 C C   . LEU B 2 311 ? 172.441 175.565 207.647 1.00 27.63 ? 311 LEU B C   1 
ATOM   5653 O O   . LEU B 2 311 ? 172.178 176.606 207.038 1.00 27.63 ? 311 LEU B O   1 
ATOM   5654 C CB  . LEU B 2 311 ? 170.163 175.532 208.688 1.00 27.63 ? 311 LEU B CB  1 
ATOM   5655 C CG  . LEU B 2 311 ? 168.757 175.019 208.394 1.00 27.63 ? 311 LEU B CG  1 
ATOM   5656 C CD1 . LEU B 2 311 ? 167.724 175.949 209.002 1.00 27.63 ? 311 LEU B CD1 1 
ATOM   5657 C CD2 . LEU B 2 311 ? 168.545 174.879 206.899 1.00 27.63 ? 311 LEU B CD2 1 
ATOM   5658 N N   . ASP B 2 312 ? 173.693 175.187 207.895 1.00 29.71 ? 312 ASP B N   1 
ATOM   5659 C CA  . ASP B 2 312 ? 174.896 175.866 207.426 1.00 29.71 ? 312 ASP B CA  1 
ATOM   5660 C C   . ASP B 2 312 ? 175.047 177.282 207.974 1.00 29.71 ? 312 ASP B C   1 
ATOM   5661 O O   . ASP B 2 312 ? 175.967 177.991 207.552 1.00 29.71 ? 312 ASP B O   1 
ATOM   5662 C CB  . ASP B 2 312 ? 174.965 175.915 205.893 1.00 29.71 ? 312 ASP B CB  1 
ATOM   5663 C CG  . ASP B 2 312 ? 174.737 174.556 205.259 1.00 29.71 ? 312 ASP B CG  1 
ATOM   5664 O OD1 . ASP B 2 312 ? 175.150 173.543 205.858 1.00 29.71 ? 312 ASP B OD1 1 
ATOM   5665 O OD2 . ASP B 2 312 ? 174.136 174.498 204.167 1.00 29.71 ? 312 ASP B OD2 1 
ATOM   5666 N N   . VAL B 2 313 ? 174.191 177.719 208.900 1.00 32.83 ? 313 VAL B N   1 
ATOM   5667 C CA  . VAL B 2 313 ? 174.218 179.101 209.367 1.00 32.83 ? 313 VAL B CA  1 
ATOM   5668 C C   . VAL B 2 313 ? 174.434 179.209 210.876 1.00 32.83 ? 313 VAL B C   1 
ATOM   5669 O O   . VAL B 2 313 ? 175.067 180.160 211.348 1.00 32.83 ? 313 VAL B O   1 
ATOM   5670 C CB  . VAL B 2 313 ? 172.926 179.828 208.946 1.00 32.83 ? 313 VAL B CB  1 
ATOM   5671 C CG1 . VAL B 2 313 ? 171.715 179.197 209.605 1.00 32.83 ? 313 VAL B CG1 1 
ATOM   5672 C CG2 . VAL B 2 313 ? 173.004 181.295 209.309 1.00 32.83 ? 313 VAL B CG2 1 
ATOM   5673 N N   . TYR B 2 314 ? 173.941 178.232 211.644 1.00 34.58 ? 314 TYR B N   1 
ATOM   5674 C CA  . TYR B 2 314 ? 173.951 178.370 213.099 1.00 34.58 ? 314 TYR B CA  1 
ATOM   5675 C C   . TYR B 2 314 ? 175.358 178.337 213.678 1.00 34.58 ? 314 TYR B C   1 
ATOM   5676 O O   . TYR B 2 314 ? 175.575 178.837 214.787 1.00 34.58 ? 314 TYR B O   1 
ATOM   5677 C CB  . TYR B 2 314 ? 173.074 177.295 213.740 1.00 34.58 ? 314 TYR B CB  1 
ATOM   5678 C CG  . TYR B 2 314 ? 171.606 177.471 213.433 1.00 34.58 ? 314 TYR B CG  1 
ATOM   5679 C CD1 . TYR B 2 314 ? 170.837 178.378 214.144 1.00 34.58 ? 314 TYR B CD1 1 
ATOM   5680 C CD2 . TYR B 2 314 ? 170.997 176.759 212.417 1.00 34.58 ? 314 TYR B CD2 1 
ATOM   5681 C CE1 . TYR B 2 314 ? 169.497 178.553 213.863 1.00 34.58 ? 314 TYR B CE1 1 
ATOM   5682 C CE2 . TYR B 2 314 ? 169.661 176.928 212.125 1.00 34.58 ? 314 TYR B CE2 1 
ATOM   5683 C CZ  . TYR B 2 314 ? 168.916 177.825 212.851 1.00 34.58 ? 314 TYR B CZ  1 
ATOM   5684 O OH  . TYR B 2 314 ? 167.582 177.992 212.561 1.00 34.58 ? 314 TYR B OH  1 
ATOM   5685 N N   . ASN B 2 315 ? 176.316 177.760 212.955 1.00 34.91 ? 315 ASN B N   1 
ATOM   5686 C CA  . ASN B 2 315 ? 177.720 177.740 213.368 1.00 34.91 ? 315 ASN B CA  1 
ATOM   5687 C C   . ASN B 2 315 ? 177.871 177.166 214.776 1.00 34.91 ? 315 ASN B C   1 
ATOM   5688 O O   . ASN B 2 315 ? 178.608 177.687 215.614 1.00 34.91 ? 315 ASN B O   1 
ATOM   5689 C CB  . ASN B 2 315 ? 178.337 179.138 213.269 1.00 34.91 ? 315 ASN B CB  1 
ATOM   5690 C CG  . ASN B 2 315 ? 179.844 179.136 213.477 1.00 34.91 ? 315 ASN B CG  1 
ATOM   5691 O OD1 . ASN B 2 315 ? 180.453 178.096 213.724 1.00 34.91 ? 315 ASN B OD1 1 
ATOM   5692 N ND2 . ASN B 2 315 ? 180.451 180.313 213.381 1.00 34.91 ? 315 ASN B ND2 1 
ATOM   5693 N N   . ASN B 2 316 ? 177.144 176.091 215.048 1.00 26.93 ? 316 ASN B N   1 
ATOM   5694 C CA  . ASN B 2 316 ? 177.304 175.375 216.301 1.00 26.93 ? 316 ASN B CA  1 
ATOM   5695 C C   . ASN B 2 316 ? 178.398 174.327 216.132 1.00 26.93 ? 316 ASN B C   1 
ATOM   5696 O O   . ASN B 2 316 ? 179.145 174.327 215.151 1.00 26.93 ? 316 ASN B O   1 
ATOM   5697 C CB  . ASN B 2 316 ? 175.981 174.751 216.741 1.00 26.93 ? 316 ASN B CB  1 
ATOM   5698 C CG  . ASN B 2 316 ? 175.569 173.585 215.872 1.00 26.93 ? 316 ASN B CG  1 
ATOM   5699 O OD1 . ASN B 2 316 ? 175.888 173.537 214.687 1.00 26.93 ? 316 ASN B OD1 1 
ATOM   5700 N ND2 . ASN B 2 316 ? 174.858 172.633 216.459 1.00 26.93 ? 316 ASN B ND2 1 
ATOM   5701 N N   . LYS B 2 317 ? 178.515 173.429 217.101 1.00 22.78 ? 317 LYS B N   1 
ATOM   5702 C CA  . LYS B 2 317 ? 179.380 172.271 216.970 1.00 22.78 ? 317 LYS B CA  1 
ATOM   5703 C C   . LYS B 2 317 ? 178.677 171.082 217.602 1.00 22.78 ? 317 LYS B C   1 
ATOM   5704 O O   . LYS B 2 317 ? 177.954 171.224 218.589 1.00 22.78 ? 317 LYS B O   1 
ATOM   5705 C CB  . LYS B 2 317 ? 180.755 172.518 217.600 1.00 22.78 ? 317 LYS B CB  1 
ATOM   5706 C CG  . LYS B 2 317 ? 180.749 172.709 219.096 1.00 22.78 ? 317 LYS B CG  1 
ATOM   5707 C CD  . LYS B 2 317 ? 182.114 173.169 219.563 1.00 22.78 ? 317 LYS B CD  1 
ATOM   5708 C CE  . LYS B 2 317 ? 183.148 172.074 219.388 1.00 22.78 ? 317 LYS B CE  1 
ATOM   5709 N NZ  . LYS B 2 317 ? 184.484 172.495 219.888 1.00 22.78 ? 317 LYS B NZ  1 
ATOM   5710 N N   . ALA B 2 318 ? 178.879 169.912 217.014 1.00 13.29 ? 318 ALA B N   1 
ATOM   5711 C CA  . ALA B 2 318 ? 178.109 168.743 217.386 1.00 13.29 ? 318 ALA B CA  1 
ATOM   5712 C C   . ALA B 2 318 ? 178.741 168.038 218.580 1.00 13.29 ? 318 ALA B C   1 
ATOM   5713 O O   . ALA B 2 318 ? 179.775 168.452 219.103 1.00 13.29 ? 318 ALA B O   1 
ATOM   5714 C CB  . ALA B 2 318 ? 177.987 167.805 216.195 1.00 13.29 ? 318 ALA B CB  1 
ATOM   5715 N N   . ALA B 2 319 ? 178.109 166.954 219.023 1.00 12.53 ? 319 ALA B N   1 
ATOM   5716 C CA  . ALA B 2 319 ? 178.617 166.187 220.149 1.00 12.53 ? 319 ALA B CA  1 
ATOM   5717 C C   . ALA B 2 319 ? 178.152 164.747 220.025 1.00 12.53 ? 319 ALA B C   1 
ATOM   5718 O O   . ALA B 2 319 ? 177.182 164.444 219.327 1.00 12.53 ? 319 ALA B O   1 
ATOM   5719 C CB  . ALA B 2 319 ? 178.167 166.779 221.486 1.00 12.53 ? 319 ALA B CB  1 
ATOM   5720 N N   . VAL B 2 320 ? 178.863 163.856 220.712 1.00 16.10 ? 320 VAL B N   1 
ATOM   5721 C CA  . VAL B 2 320 ? 178.573 162.427 220.687 1.00 16.10 ? 320 VAL B CA  1 
ATOM   5722 C C   . VAL B 2 320 ? 178.778 161.891 222.098 1.00 16.10 ? 320 VAL B C   1 
ATOM   5723 O O   . VAL B 2 320 ? 179.912 161.853 222.589 1.00 16.10 ? 320 VAL B O   1 
ATOM   5724 C CB  . VAL B 2 320 ? 179.460 161.670 219.692 1.00 16.10 ? 320 VAL B CB  1 
ATOM   5725 C CG1 . VAL B 2 320 ? 179.347 160.184 219.910 1.00 16.10 ? 320 VAL B CG1 1 
ATOM   5726 C CG2 . VAL B 2 320 ? 179.078 162.024 218.281 1.00 16.10 ? 320 VAL B CG2 1 
ATOM   5727 N N   . LEU B 2 321 ? 177.693 161.501 222.755 1.00 15.02 ? 321 LEU B N   1 
ATOM   5728 C CA  . LEU B 2 321 ? 177.809 160.880 224.063 1.00 15.02 ? 321 LEU B CA  1 
ATOM   5729 C C   . LEU B 2 321 ? 178.420 159.494 223.918 1.00 15.02 ? 321 LEU B C   1 
ATOM   5730 O O   . LEU B 2 321 ? 178.294 158.846 222.879 1.00 15.02 ? 321 LEU B O   1 
ATOM   5731 C CB  . LEU B 2 321 ? 176.438 160.796 224.730 1.00 15.02 ? 321 LEU B CB  1 
ATOM   5732 C CG  . LEU B 2 321 ? 176.347 160.535 226.234 1.00 15.02 ? 321 LEU B CG  1 
ATOM   5733 C CD1 . LEU B 2 321 ? 175.118 161.218 226.794 1.00 15.02 ? 321 LEU B CD1 1 
ATOM   5734 C CD2 . LEU B 2 321 ? 176.301 159.054 226.547 1.00 15.02 ? 321 LEU B CD2 1 
ATOM   5735 N N   . LYS B 2 322 ? 179.105 159.040 224.963 1.00 20.43 ? 322 LYS B N   1 
ATOM   5736 C CA  . LYS B 2 322 ? 179.660 157.697 224.979 1.00 20.43 ? 322 LYS B CA  1 
ATOM   5737 C C   . LYS B 2 322 ? 179.558 157.146 226.388 1.00 20.43 ? 322 LYS B C   1 
ATOM   5738 O O   . LYS B 2 322 ? 180.069 157.754 227.333 1.00 20.43 ? 322 LYS B O   1 
ATOM   5739 C CB  . LYS B 2 322 ? 181.116 157.689 224.508 1.00 20.43 ? 322 LYS B CB  1 
ATOM   5740 C CG  . LYS B 2 322 ? 181.750 156.312 224.499 1.00 20.43 ? 322 LYS B CG  1 
ATOM   5741 C CD  . LYS B 2 322 ? 183.219 156.378 224.122 1.00 20.43 ? 322 LYS B CD  1 
ATOM   5742 C CE  . LYS B 2 322 ? 183.402 156.569 222.626 1.00 20.43 ? 322 LYS B CE  1 
ATOM   5743 N NZ  . LYS B 2 322 ? 183.111 155.318 221.871 1.00 20.43 ? 322 LYS B NZ  1 
ATOM   5744 N N   . TYR B 2 323 ? 178.907 155.996 226.524 1.00 25.52 ? 323 TYR B N   1 
ATOM   5745 C CA  . TYR B 2 323 ? 178.641 155.383 227.818 1.00 25.52 ? 323 TYR B CA  1 
ATOM   5746 C C   . TYR B 2 323 ? 179.565 154.189 227.994 1.00 25.52 ? 323 TYR B C   1 
ATOM   5747 O O   . TYR B 2 323 ? 179.582 153.289 227.150 1.00 25.52 ? 323 TYR B O   1 
ATOM   5748 C CB  . TYR B 2 323 ? 177.178 154.956 227.922 1.00 25.52 ? 323 TYR B CB  1 
ATOM   5749 C CG  . TYR B 2 323 ? 176.799 154.401 229.269 1.00 25.52 ? 323 TYR B CG  1 
ATOM   5750 C CD1 . TYR B 2 323 ? 176.799 155.204 230.394 1.00 25.52 ? 323 TYR B CD1 1 
ATOM   5751 C CD2 . TYR B 2 323 ? 176.439 153.074 229.414 1.00 25.52 ? 323 TYR B CD2 1 
ATOM   5752 C CE1 . TYR B 2 323 ? 176.455 154.700 231.629 1.00 25.52 ? 323 TYR B CE1 1 
ATOM   5753 C CE2 . TYR B 2 323 ? 176.091 152.561 230.644 1.00 25.52 ? 323 TYR B CE2 1 
ATOM   5754 C CZ  . TYR B 2 323 ? 176.101 153.378 231.748 1.00 25.52 ? 323 TYR B CZ  1 
ATOM   5755 O OH  . TYR B 2 323 ? 175.754 152.869 232.978 1.00 25.52 ? 323 TYR B OH  1 
ATOM   5756 N N   . GLU B 2 324 ? 180.328 154.181 229.084 1.00 35.07 ? 324 GLU B N   1 
ATOM   5757 C CA  . GLU B 2 324 ? 181.240 153.079 229.349 1.00 35.07 ? 324 GLU B CA  1 
ATOM   5758 C C   . GLU B 2 324 ? 181.682 153.139 230.803 1.00 35.07 ? 324 GLU B C   1 
ATOM   5759 O O   . GLU B 2 324 ? 181.970 154.220 231.322 1.00 35.07 ? 324 GLU B O   1 
ATOM   5760 C CB  . GLU B 2 324 ? 182.460 153.128 228.423 1.00 35.07 ? 324 GLU B CB  1 
ATOM   5761 N N   . ASN B 2 325 ? 181.737 151.971 231.444 1.00 42.79 ? 325 ASN B N   1 
ATOM   5762 C CA  . ASN B 2 325 ? 182.177 151.850 232.835 1.00 42.79 ? 325 ASN B CA  1 
ATOM   5763 C C   . ASN B 2 325 ? 181.376 152.773 233.751 1.00 42.79 ? 325 ASN B C   1 
ATOM   5764 O O   . ASN B 2 325 ? 181.925 153.442 234.629 1.00 42.79 ? 325 ASN B O   1 
ATOM   5765 C CB  . ASN B 2 325 ? 183.676 152.122 232.961 1.00 42.79 ? 325 ASN B CB  1 
ATOM   5766 C CG  . ASN B 2 325 ? 184.521 150.942 232.525 1.00 42.79 ? 325 ASN B CG  1 
ATOM   5767 O OD1 . ASN B 2 325 ? 184.833 150.788 231.344 1.00 42.79 ? 325 ASN B OD1 1 
ATOM   5768 N ND2 . ASN B 2 325 ? 184.896 150.099 233.480 1.00 42.79 ? 325 ASN B ND2 1 
ATOM   5769 N N   . ASN B 2 326 ? 180.062 152.814 233.529 1.00 39.75 ? 326 ASN B N   1 
ATOM   5770 C CA  . ASN B 2 326 ? 179.130 153.634 234.301 1.00 39.75 ? 326 ASN B CA  1 
ATOM   5771 C C   . ASN B 2 326 ? 179.468 155.119 234.232 1.00 39.75 ? 326 ASN B C   1 
ATOM   5772 O O   . ASN B 2 326 ? 179.061 155.892 235.104 1.00 39.75 ? 326 ASN B O   1 
ATOM   5773 C CB  . ASN B 2 326 ? 179.066 153.177 235.762 1.00 39.75 ? 326 ASN B CB  1 
ATOM   5774 C CG  . ASN B 2 326 ? 178.392 151.833 235.918 1.00 39.75 ? 326 ASN B CG  1 
ATOM   5775 O OD1 . ASN B 2 326 ? 177.379 151.556 235.276 1.00 39.75 ? 326 ASN B OD1 1 
ATOM   5776 N ND2 . ASN B 2 326 ? 178.952 150.986 236.774 1.00 39.75 ? 326 ASN B ND2 1 
ATOM   5777 N N   . VAL B 2 327 ? 180.204 155.535 233.205 1.00 37.86 ? 327 VAL B N   1 
ATOM   5778 C CA  . VAL B 2 327 ? 180.603 156.924 233.026 1.00 37.86 ? 327 VAL B CA  1 
ATOM   5779 C C   . VAL B 2 327 ? 180.199 157.362 231.627 1.00 37.86 ? 327 VAL B C   1 
ATOM   5780 O O   . VAL B 2 327 ? 180.480 156.662 230.647 1.00 37.86 ? 327 VAL B O   1 
ATOM   5781 C CB  . VAL B 2 327 ? 182.117 157.118 233.235 1.00 37.86 ? 327 VAL B CB  1 
ATOM   5782 C CG1 . VAL B 2 327 ? 182.505 158.566 232.987 1.00 37.86 ? 327 VAL B CG1 1 
ATOM   5783 C CG2 . VAL B 2 327 ? 182.518 156.687 234.636 1.00 37.86 ? 327 VAL B CG2 1 
ATOM   5784 N N   . MET B 2 328 ? 179.530 158.507 231.537 1.00 32.96 ? 328 MET B N   1 
ATOM   5785 C CA  . MET B 2 328 ? 179.192 159.119 230.261 1.00 32.96 ? 328 MET B CA  1 
ATOM   5786 C C   . MET B 2 328 ? 180.210 160.207 229.960 1.00 32.96 ? 328 MET B C   1 
ATOM   5787 O O   . MET B 2 328 ? 180.225 161.247 230.626 1.00 32.96 ? 328 MET B O   1 
ATOM   5788 C CB  . MET B 2 328 ? 177.782 159.708 230.278 1.00 32.96 ? 328 MET B CB  1 
ATOM   5789 C CG  . MET B 2 328 ? 176.672 158.689 230.398 1.00 32.96 ? 328 MET B CG  1 
ATOM   5790 S SD  . MET B 2 328 ? 175.042 159.451 230.344 1.00 32.96 ? 328 MET B SD  1 
ATOM   5791 C CE  . MET B 2 328 ? 174.962 160.201 231.966 1.00 32.96 ? 328 MET B CE  1 
ATOM   5792 N N   . ASN B 2 329 ? 181.051 159.971 228.961 1.00 24.78 ? 329 ASN B N   1 
ATOM   5793 C CA  . ASN B 2 329 ? 181.997 160.973 228.495 1.00 24.78 ? 329 ASN B CA  1 
ATOM   5794 C C   . ASN B 2 329 ? 181.600 161.438 227.101 1.00 24.78 ? 329 ASN B C   1 
ATOM   5795 O O   . ASN B 2 329 ? 181.115 160.651 226.285 1.00 24.78 ? 329 ASN B O   1 
ATOM   5796 C CB  . ASN B 2 329 ? 183.437 160.441 228.524 1.00 24.78 ? 329 ASN B CB  1 
ATOM   5797 C CG  . ASN B 2 329 ? 183.620 159.165 227.728 1.00 24.78 ? 329 ASN B CG  1 
ATOM   5798 O OD1 . ASN B 2 329 ? 182.701 158.684 227.074 1.00 24.78 ? 329 ASN B OD1 1 
ATOM   5799 N ND2 . ASN B 2 329 ? 184.823 158.606 227.787 1.00 24.78 ? 329 ASN B ND2 1 
ATOM   5800 N N   . ILE B 2 330 ? 181.776 162.726 226.841 1.00 18.50 ? 330 ILE B N   1 
ATOM   5801 C CA  . ILE B 2 330 ? 181.221 163.364 225.656 1.00 18.50 ? 330 ILE B CA  1 
ATOM   5802 C C   . ILE B 2 330 ? 182.363 163.755 224.733 1.00 18.50 ? 330 ILE B C   1 
ATOM   5803 O O   . ILE B 2 330 ? 183.290 164.462 225.146 1.00 18.50 ? 330 ILE B O   1 
ATOM   5804 C CB  . ILE B 2 330 ? 180.365 164.578 226.033 1.00 18.50 ? 330 ILE B CB  1 
ATOM   5805 C CG1 . ILE B 2 330 ? 179.097 164.099 226.732 1.00 18.50 ? 330 ILE B CG1 1 
ATOM   5806 C CG2 . ILE B 2 330 ? 180.027 165.395 224.809 1.00 18.50 ? 330 ILE B CG2 1 
ATOM   5807 C CD1 . ILE B 2 330 ? 178.240 165.202 227.255 1.00 18.50 ? 330 ILE B CD1 1 
ATOM   5808 N N   . ARG B 2 331 ? 182.301 163.295 223.485 1.00 20.49 ? 331 ARG B N   1 
ATOM   5809 C CA  . ARG B 2 331 ? 183.283 163.662 222.475 1.00 20.49 ? 331 ARG B CA  1 
ATOM   5810 C C   . ARG B 2 331 ? 182.732 164.816 221.649 1.00 20.49 ? 331 ARG B C   1 
ATOM   5811 O O   . ARG B 2 331 ? 181.627 164.724 221.104 1.00 20.49 ? 331 ARG B O   1 
ATOM   5812 C CB  . ARG B 2 331 ? 183.609 162.471 221.577 1.00 20.49 ? 331 ARG B CB  1 
ATOM   5813 C CG  . ARG B 2 331 ? 184.218 161.287 222.300 1.00 20.49 ? 331 ARG B CG  1 
ATOM   5814 C CD  . ARG B 2 331 ? 185.570 161.651 222.881 1.00 20.49 ? 331 ARG B CD  1 
ATOM   5815 N NE  . ARG B 2 331 ? 186.510 162.106 221.860 1.00 20.49 ? 331 ARG B NE  1 
ATOM   5816 C CZ  . ARG B 2 331 ? 187.303 161.304 221.158 1.00 20.49 ? 331 ARG B CZ  1 
ATOM   5817 N NH1 . ARG B 2 331 ? 188.127 161.811 220.252 1.00 20.49 ? 331 ARG B NH1 1 
ATOM   5818 N NH2 . ARG B 2 331 ? 187.275 159.995 221.365 1.00 20.49 ? 331 ARG B NH2 1 
ATOM   5819 N N   . GLN B 2 332 ? 183.498 165.896 221.552 1.00 18.59 ? 332 GLN B N   1 
ATOM   5820 C CA  . GLN B 2 332 ? 183.072 167.047 220.771 1.00 18.59 ? 332 GLN B CA  1 
ATOM   5821 C C   . GLN B 2 332 ? 183.312 166.748 219.294 1.00 18.59 ? 332 GLN B C   1 
ATOM   5822 O O   . GLN B 2 332 ? 183.599 165.612 218.908 1.00 18.59 ? 332 GLN B O   1 
ATOM   5823 C CB  . GLN B 2 332 ? 183.777 168.310 221.252 1.00 18.59 ? 332 GLN B CB  1 
ATOM   5824 C CG  . GLN B 2 332 ? 183.303 168.782 222.619 1.00 18.59 ? 332 GLN B CG  1 
ATOM   5825 C CD  . GLN B 2 332 ? 182.043 169.620 222.544 1.00 18.59 ? 332 GLN B CD  1 
ATOM   5826 O OE1 . GLN B 2 332 ? 181.675 170.111 221.481 1.00 18.59 ? 332 GLN B OE1 1 
ATOM   5827 N NE2 . GLN B 2 332 ? 181.371 169.781 223.676 1.00 18.59 ? 332 GLN B NE2 1 
ATOM   5828 N N   . PHE B 2 333 ? 183.199 167.758 218.441 1.00 17.68 ? 333 PHE B N   1 
ATOM   5829 C CA  . PHE B 2 333 ? 182.974 167.469 217.033 1.00 17.68 ? 333 PHE B CA  1 
ATOM   5830 C C   . PHE B 2 333 ? 183.324 168.735 216.261 1.00 17.68 ? 333 PHE B C   1 
ATOM   5831 O O   . PHE B 2 333 ? 183.568 169.790 216.853 1.00 17.68 ? 333 PHE B O   1 
ATOM   5832 C CB  . PHE B 2 333 ? 181.513 167.065 216.841 1.00 17.68 ? 333 PHE B CB  1 
ATOM   5833 C CG  . PHE B 2 333 ? 181.238 166.246 215.626 1.00 17.68 ? 333 PHE B CG  1 
ATOM   5834 C CD1 . PHE B 2 333 ? 181.501 164.894 215.644 1.00 17.68 ? 333 PHE B CD1 1 
ATOM   5835 C CD2 . PHE B 2 333 ? 180.689 166.800 214.491 1.00 17.68 ? 333 PHE B CD2 1 
ATOM   5836 C CE1 . PHE B 2 333 ? 181.230 164.119 214.563 1.00 17.68 ? 333 PHE B CE1 1 
ATOM   5837 C CE2 . PHE B 2 333 ? 180.420 166.022 213.399 1.00 17.68 ? 333 PHE B CE2 1 
ATOM   5838 C CZ  . PHE B 2 333 ? 180.693 164.680 213.435 1.00 17.68 ? 333 PHE B CZ  1 
ATOM   5839 N N   . ASN B 2 334 ? 183.345 168.629 214.934 1.00 18.97 ? 334 ASN B N   1 
ATOM   5840 C CA  . ASN B 2 334 ? 183.601 169.798 214.102 1.00 18.97 ? 334 ASN B CA  1 
ATOM   5841 C C   . ASN B 2 334 ? 183.027 169.567 212.712 1.00 18.97 ? 334 ASN B C   1 
ATOM   5842 O O   . ASN B 2 334 ? 182.750 168.433 212.315 1.00 18.97 ? 334 ASN B O   1 
ATOM   5843 C CB  . ASN B 2 334 ? 185.097 170.115 214.015 1.00 18.97 ? 334 ASN B CB  1 
ATOM   5844 N N   . CYS B 2 335 ? 182.867 170.660 211.969 1.00 19.19 ? 335 CYS B N   1 
ATOM   5845 C CA  . CYS B 2 335 ? 182.259 170.597 210.647 1.00 19.19 ? 335 CYS B CA  1 
ATOM   5846 C C   . CYS B 2 335 ? 183.233 169.994 209.635 1.00 19.19 ? 335 CYS B C   1 
ATOM   5847 O O   . CYS B 2 335 ? 184.337 169.559 209.969 1.00 19.19 ? 335 CYS B O   1 
ATOM   5848 C CB  . CYS B 2 335 ? 181.816 171.986 210.202 1.00 19.19 ? 335 CYS B CB  1 
ATOM   5849 S SG  . CYS B 2 335 ? 183.166 173.154 209.940 1.00 19.19 ? 335 CYS B SG  1 
ATOM   5850 N N   . SER B 2 336 ? 182.810 169.969 208.372 1.00 14.55 ? 336 SER B N   1 
ATOM   5851 C CA  . SER B 2 336 ? 183.629 169.435 207.292 1.00 14.55 ? 336 SER B CA  1 
ATOM   5852 C C   . SER B 2 336 ? 183.097 169.965 205.970 1.00 14.55 ? 336 SER B C   1 
ATOM   5853 O O   . SER B 2 336 ? 181.881 170.123 205.819 1.00 14.55 ? 336 SER B O   1 
ATOM   5854 C CB  . SER B 2 336 ? 183.621 167.901 207.297 1.00 14.55 ? 336 SER B CB  1 
ATOM   5855 O OG  . SER B 2 336 ? 184.415 167.397 208.354 1.00 14.55 ? 336 SER B OG  1 
ATOM   5856 N N   . PRO B 2 337 ? 183.965 170.232 204.999 1.00 13.10 ? 337 PRO B N   1 
ATOM   5857 C CA  . PRO B 2 337 ? 183.505 170.805 203.730 1.00 13.10 ? 337 PRO B CA  1 
ATOM   5858 C C   . PRO B 2 337 ? 182.740 169.781 202.910 1.00 13.10 ? 337 PRO B C   1 
ATOM   5859 O O   . PRO B 2 337 ? 182.809 168.576 203.143 1.00 13.10 ? 337 PRO B O   1 
ATOM   5860 C CB  . PRO B 2 337 ? 184.803 171.215 203.038 1.00 13.10 ? 337 PRO B CB  1 
ATOM   5861 C CG  . PRO B 2 337 ? 185.818 170.278 203.580 1.00 13.10 ? 337 PRO B CG  1 
ATOM   5862 C CD  . PRO B 2 337 ? 185.411 169.961 204.991 1.00 13.10 ? 337 PRO B CD  1 
ATOM   5863 N N   . HIS B 2 338 ? 182.006 170.284 201.923 1.00 12.56 ? 338 HIS B N   1 
ATOM   5864 C CA  . HIS B 2 338 ? 181.129 169.451 201.114 1.00 12.56 ? 338 HIS B CA  1 
ATOM   5865 C C   . HIS B 2 338 ? 180.914 170.135 199.773 1.00 12.56 ? 338 HIS B C   1 
ATOM   5866 O O   . HIS B 2 338 ? 181.136 171.343 199.650 1.00 12.56 ? 338 HIS B O   1 
ATOM   5867 C CB  . HIS B 2 338 ? 179.786 169.214 201.819 1.00 12.56 ? 338 HIS B CB  1 
ATOM   5868 C CG  . HIS B 2 338 ? 179.052 170.472 202.155 1.00 12.56 ? 338 HIS B CG  1 
ATOM   5869 N ND1 . HIS B 2 338 ? 177.888 170.846 201.520 1.00 12.56 ? 338 HIS B ND1 1 
ATOM   5870 C CD2 . HIS B 2 338 ? 179.312 171.441 203.062 1.00 12.56 ? 338 HIS B CD2 1 
ATOM   5871 C CE1 . HIS B 2 338 ? 177.464 171.992 202.020 1.00 12.56 ? 338 HIS B CE1 1 
ATOM   5872 N NE2 . HIS B 2 338 ? 178.311 172.375 202.957 1.00 12.56 ? 338 HIS B NE2 1 
ATOM   5873 N N   . PRO B 2 339 ? 180.490 169.392 198.749 1.00 12.32 ? 339 PRO B N   1 
ATOM   5874 C CA  . PRO B 2 339 ? 180.169 170.017 197.460 1.00 12.32 ? 339 PRO B CA  1 
ATOM   5875 C C   . PRO B 2 339 ? 178.956 170.930 197.522 1.00 12.32 ? 339 PRO B C   1 
ATOM   5876 O O   . PRO B 2 339 ? 178.318 171.049 198.571 1.00 12.32 ? 339 PRO B O   1 
ATOM   5877 C CB  . PRO B 2 339 ? 179.905 168.817 196.547 1.00 12.32 ? 339 PRO B CB  1 
ATOM   5878 C CG  . PRO B 2 339 ? 180.613 167.696 197.181 1.00 12.32 ? 339 PRO B CG  1 
ATOM   5879 C CD  . PRO B 2 339 ? 180.514 167.927 198.649 1.00 12.32 ? 339 PRO B CD  1 
ATOM   5880 N N   . TYR B 2 340 ? 178.620 171.567 196.403 1.00 10.26 ? 340 TYR B N   1 
ATOM   5881 C CA  . TYR B 2 340 ? 177.548 172.551 196.351 1.00 10.26 ? 340 TYR B CA  1 
ATOM   5882 C C   . TYR B 2 340 ? 176.483 172.113 195.357 1.00 10.26 ? 340 TYR B C   1 
ATOM   5883 O O   . TYR B 2 340 ? 176.799 171.750 194.222 1.00 10.26 ? 340 TYR B O   1 
ATOM   5884 C CB  . TYR B 2 340 ? 178.091 173.924 195.963 1.00 10.26 ? 340 TYR B CB  1 
ATOM   5885 C CG  . TYR B 2 340 ? 177.047 175.013 195.920 1.00 10.26 ? 340 TYR B CG  1 
ATOM   5886 C CD1 . TYR B 2 340 ? 176.164 175.195 196.970 1.00 10.26 ? 340 TYR B CD1 1 
ATOM   5887 C CD2 . TYR B 2 340 ? 176.950 175.865 194.834 1.00 10.26 ? 340 TYR B CD2 1 
ATOM   5888 C CE1 . TYR B 2 340 ? 175.213 176.191 196.936 1.00 10.26 ? 340 TYR B CE1 1 
ATOM   5889 C CE2 . TYR B 2 340 ? 176.002 176.863 194.793 1.00 10.26 ? 340 TYR B CE2 1 
ATOM   5890 C CZ  . TYR B 2 340 ? 175.139 177.020 195.846 1.00 10.26 ? 340 TYR B CZ  1 
ATOM   5891 O OH  . TYR B 2 340 ? 174.193 178.013 195.811 1.00 10.26 ? 340 TYR B OH  1 
ATOM   5892 N N   . TRP B 2 341 ? 175.227 172.152 195.790 1.00 14.73 ? 341 TRP B N   1 
ATOM   5893 C CA  . TRP B 2 341 ? 174.070 171.917 194.941 1.00 14.73 ? 341 TRP B CA  1 
ATOM   5894 C C   . TRP B 2 341 ? 173.230 173.182 194.890 1.00 14.73 ? 341 TRP B C   1 
ATOM   5895 O O   . TRP B 2 341 ? 173.178 173.948 195.854 1.00 14.73 ? 341 TRP B O   1 
ATOM   5896 C CB  . TRP B 2 341 ? 173.199 170.775 195.466 1.00 14.73 ? 341 TRP B CB  1 
ATOM   5897 C CG  . TRP B 2 341 ? 173.666 169.396 195.147 1.00 14.73 ? 341 TRP B CG  1 
ATOM   5898 C CD1 . TRP B 2 341 ? 174.603 168.675 195.818 1.00 14.73 ? 341 TRP B CD1 1 
ATOM   5899 C CD2 . TRP B 2 341 ? 173.187 168.553 194.097 1.00 14.73 ? 341 TRP B CD2 1 
ATOM   5900 N NE1 . TRP B 2 341 ? 174.750 167.439 195.242 1.00 14.73 ? 341 TRP B NE1 1 
ATOM   5901 C CE2 . TRP B 2 341 ? 173.890 167.341 194.182 1.00 14.73 ? 341 TRP B CE2 1 
ATOM   5902 C CE3 . TRP B 2 341 ? 172.239 168.711 193.086 1.00 14.73 ? 341 TRP B CE3 1 
ATOM   5903 C CZ2 . TRP B 2 341 ? 173.675 166.295 193.297 1.00 14.73 ? 341 TRP B CZ2 1 
ATOM   5904 C CZ3 . TRP B 2 341 ? 172.026 167.671 192.211 1.00 14.73 ? 341 TRP B CZ3 1 
ATOM   5905 C CH2 . TRP B 2 341 ? 172.740 166.479 192.320 1.00 14.73 ? 341 TRP B CH2 1 
ATOM   5906 N N   . LEU B 2 342 ? 172.566 173.398 193.764 1.00 14.50 ? 342 LEU B N   1 
ATOM   5907 C CA  . LEU B 2 342 ? 171.679 174.540 193.658 1.00 14.50 ? 342 LEU B CA  1 
ATOM   5908 C C   . LEU B 2 342 ? 170.425 174.296 194.495 1.00 14.50 ? 342 LEU B C   1 
ATOM   5909 O O   . LEU B 2 342 ? 170.042 173.147 194.722 1.00 14.50 ? 342 LEU B O   1 
ATOM   5910 C CB  . LEU B 2 342 ? 171.303 174.792 192.203 1.00 14.50 ? 342 LEU B CB  1 
ATOM   5911 C CG  . LEU B 2 342 ? 172.326 175.624 191.439 1.00 14.50 ? 342 LEU B CG  1 
ATOM   5912 C CD1 . LEU B 2 342 ? 171.863 175.853 190.029 1.00 14.50 ? 342 LEU B CD1 1 
ATOM   5913 C CD2 . LEU B 2 342 ? 172.559 176.938 192.144 1.00 14.50 ? 342 LEU B CD2 1 
ATOM   5914 N N   . PRO B 2 343 ? 169.779 175.356 194.980 1.00 13.25 ? 343 PRO B N   1 
ATOM   5915 C CA  . PRO B 2 343 ? 168.565 175.166 195.779 1.00 13.25 ? 343 PRO B CA  1 
ATOM   5916 C C   . PRO B 2 343 ? 167.505 174.422 194.986 1.00 13.25 ? 343 PRO B C   1 
ATOM   5917 O O   . PRO B 2 343 ? 167.270 174.710 193.813 1.00 13.25 ? 343 PRO B O   1 
ATOM   5918 C CB  . PRO B 2 343 ? 168.129 176.597 196.108 1.00 13.25 ? 343 PRO B CB  1 
ATOM   5919 C CG  . PRO B 2 343 ? 168.778 177.437 195.077 1.00 13.25 ? 343 PRO B CG  1 
ATOM   5920 C CD  . PRO B 2 343 ? 170.091 176.782 194.810 1.00 13.25 ? 343 PRO B CD  1 
ATOM   5921 N N   . ASN B 2 344 ? 166.875 173.451 195.637 1.00 14.20 ? 344 ASN B N   1 
ATOM   5922 C CA  . ASN B 2 344 ? 165.822 172.633 195.047 1.00 14.20 ? 344 ASN B CA  1 
ATOM   5923 C C   . ASN B 2 344 ? 166.294 171.872 193.812 1.00 14.20 ? 344 ASN B C   1 
ATOM   5924 O O   . ASN B 2 344 ? 165.473 171.456 192.991 1.00 14.20 ? 344 ASN B O   1 
ATOM   5925 C CB  . ASN B 2 344 ? 164.595 173.481 194.710 1.00 14.20 ? 344 ASN B CB  1 
ATOM   5926 C CG  . ASN B 2 344 ? 163.320 172.681 194.726 1.00 14.20 ? 344 ASN B CG  1 
ATOM   5927 O OD1 . ASN B 2 344 ? 162.878 172.223 195.778 1.00 14.20 ? 344 ASN B OD1 1 
ATOM   5928 N ND2 . ASN B 2 344 ? 162.715 172.508 193.559 1.00 14.20 ? 344 ASN B ND2 1 
ATOM   5929 N N   . PHE B 2 345 ? 167.607 171.681 193.669 1.00 16.76 ? 345 PHE B N   1 
ATOM   5930 C CA  . PHE B 2 345 ? 168.196 170.869 192.602 1.00 16.76 ? 345 PHE B CA  1 
ATOM   5931 C C   . PHE B 2 345 ? 167.749 171.339 191.215 1.00 16.76 ? 345 PHE B C   1 
ATOM   5932 O O   . PHE B 2 345 ? 167.083 170.619 190.471 1.00 16.76 ? 345 PHE B O   1 
ATOM   5933 C CB  . PHE B 2 345 ? 167.870 169.385 192.798 1.00 16.76 ? 345 PHE B CB  1 
ATOM   5934 C CG  . PHE B 2 345 ? 168.070 168.894 194.199 1.00 16.76 ? 345 PHE B CG  1 
ATOM   5935 C CD1 . PHE B 2 345 ? 169.301 168.439 194.616 1.00 16.76 ? 345 PHE B CD1 1 
ATOM   5936 C CD2 . PHE B 2 345 ? 167.018 168.861 195.092 1.00 16.76 ? 345 PHE B CD2 1 
ATOM   5937 C CE1 . PHE B 2 345 ? 169.482 167.981 195.898 1.00 16.76 ? 345 PHE B CE1 1 
ATOM   5938 C CE2 . PHE B 2 345 ? 167.196 168.402 196.375 1.00 16.76 ? 345 PHE B CE2 1 
ATOM   5939 C CZ  . PHE B 2 345 ? 168.427 167.963 196.776 1.00 16.76 ? 345 PHE B CZ  1 
ATOM   5940 N N   . MET B 2 346 ? 168.129 172.565 190.872 1.00 16.17 ? 346 MET B N   1 
ATOM   5941 C CA  . MET B 2 346 ? 167.873 173.117 189.550 1.00 16.17 ? 346 MET B CA  1 
ATOM   5942 C C   . MET B 2 346 ? 169.132 173.009 188.705 1.00 16.17 ? 346 MET B C   1 
ATOM   5943 O O   . MET B 2 346 ? 170.219 173.377 189.158 1.00 16.17 ? 346 MET B O   1 
ATOM   5944 C CB  . MET B 2 346 ? 167.441 174.580 189.624 1.00 16.17 ? 346 MET B CB  1 
ATOM   5945 C CG  . MET B 2 346 ? 166.180 174.845 190.397 1.00 16.17 ? 346 MET B CG  1 
ATOM   5946 S SD  . MET B 2 346 ? 165.829 176.607 190.399 1.00 16.17 ? 346 MET B SD  1 
ATOM   5947 C CE  . MET B 2 346 ? 167.288 177.235 191.214 1.00 16.17 ? 346 MET B CE  1 
ATOM   5948 N N   . ASP B 2 347 ? 168.988 172.506 187.483 1.00 16.92 ? 347 ASP B N   1 
ATOM   5949 C CA  . ASP B 2 347 ? 170.098 172.550 186.549 1.00 16.92 ? 347 ASP B CA  1 
ATOM   5950 C C   . ASP B 2 347 ? 170.270 173.967 186.013 1.00 16.92 ? 347 ASP B C   1 
ATOM   5951 O O   . ASP B 2 347 ? 169.366 174.800 186.093 1.00 16.92 ? 347 ASP B O   1 
ATOM   5952 C CB  . ASP B 2 347 ? 169.878 171.561 185.409 1.00 16.92 ? 347 ASP B CB  1 
ATOM   5953 C CG  . ASP B 2 347 ? 168.482 171.625 184.854 1.00 16.92 ? 347 ASP B CG  1 
ATOM   5954 O OD1 . ASP B 2 347 ? 167.679 172.430 185.363 1.00 16.92 ? 347 ASP B OD1 1 
ATOM   5955 O OD2 . ASP B 2 347 ? 168.181 170.859 183.920 1.00 16.92 ? 347 ASP B OD2 1 
ATOM   5956 N N   . VAL B 2 348 ? 171.454 174.237 185.462 1.00 18.96 ? 348 VAL B N   1 
ATOM   5957 C CA  . VAL B 2 348 ? 171.801 175.610 185.115 1.00 18.96 ? 348 VAL B CA  1 
ATOM   5958 C C   . VAL B 2 348 ? 170.899 176.161 184.015 1.00 18.96 ? 348 VAL B C   1 
ATOM   5959 O O   . VAL B 2 348 ? 170.668 177.374 183.948 1.00 18.96 ? 348 VAL B O   1 
ATOM   5960 C CB  . VAL B 2 348 ? 173.285 175.701 184.728 1.00 18.96 ? 348 VAL B CB  1 
ATOM   5961 C CG1 . VAL B 2 348 ? 174.147 175.495 185.952 1.00 18.96 ? 348 VAL B CG1 1 
ATOM   5962 C CG2 . VAL B 2 348 ? 173.613 174.677 183.676 1.00 18.96 ? 348 VAL B CG2 1 
ATOM   5963 N N   . PHE B 2 349 ? 170.377 175.302 183.137 1.00 19.48 ? 349 PHE B N   1 
ATOM   5964 C CA  . PHE B 2 349 ? 169.471 175.783 182.098 1.00 19.48 ? 349 PHE B CA  1 
ATOM   5965 C C   . PHE B 2 349 ? 168.200 176.359 182.707 1.00 19.48 ? 349 PHE B C   1 
ATOM   5966 O O   . PHE B 2 349 ? 167.822 177.499 182.417 1.00 19.48 ? 349 PHE B O   1 
ATOM   5967 C CB  . PHE B 2 349 ? 169.144 174.654 181.124 1.00 19.48 ? 349 PHE B CB  1 
ATOM   5968 C CG  . PHE B 2 349 ? 170.354 174.025 180.508 1.00 19.48 ? 349 PHE B CG  1 
ATOM   5969 C CD1 . PHE B 2 349 ? 171.405 174.805 180.071 1.00 19.48 ? 349 PHE B CD1 1 
ATOM   5970 C CD2 . PHE B 2 349 ? 170.447 172.654 180.378 1.00 19.48 ? 349 PHE B CD2 1 
ATOM   5971 C CE1 . PHE B 2 349 ? 172.521 174.232 179.511 1.00 19.48 ? 349 PHE B CE1 1 
ATOM   5972 C CE2 . PHE B 2 349 ? 171.563 172.077 179.820 1.00 19.48 ? 349 PHE B CE2 1 
ATOM   5973 C CZ  . PHE B 2 349 ? 172.600 172.867 179.385 1.00 19.48 ? 349 PHE B CZ  1 
ATOM   5974 N N   . THR B 2 350 ? 167.532 175.589 183.571 1.00 22.21 ? 350 THR B N   1 
ATOM   5975 C CA  . THR B 2 350 ? 166.363 176.107 184.277 1.00 22.21 ? 350 THR B CA  1 
ATOM   5976 C C   . THR B 2 350 ? 166.747 177.240 185.214 1.00 22.21 ? 350 THR B C   1 
ATOM   5977 O O   . THR B 2 350 ? 165.912 178.089 185.545 1.00 22.21 ? 350 THR B O   1 
ATOM   5978 C CB  . THR B 2 350 ? 165.680 174.986 185.061 1.00 22.21 ? 350 THR B CB  1 
ATOM   5979 O OG1 . THR B 2 350 ? 165.485 173.851 184.210 1.00 22.21 ? 350 THR B OG1 1 
ATOM   5980 C CG2 . THR B 2 350 ? 164.334 175.440 185.590 1.00 22.21 ? 350 THR B CG2 1 
ATOM   5981 N N   . TRP B 2 351 ? 168.006 177.273 185.644 1.00 21.39 ? 351 TRP B N   1 
ATOM   5982 C CA  . TRP B 2 351 ? 168.460 178.305 186.564 1.00 21.39 ? 351 TRP B CA  1 
ATOM   5983 C C   . TRP B 2 351 ? 168.530 179.665 185.884 1.00 21.39 ? 351 TRP B C   1 
ATOM   5984 O O   . TRP B 2 351 ? 168.054 180.666 186.429 1.00 21.39 ? 351 TRP B O   1 
ATOM   5985 C CB  . TRP B 2 351 ? 169.820 177.914 187.129 1.00 21.39 ? 351 TRP B CB  1 
ATOM   5986 C CG  . TRP B 2 351 ? 170.399 178.890 188.074 1.00 21.39 ? 351 TRP B CG  1 
ATOM   5987 C CD1 . TRP B 2 351 ? 169.740 179.591 189.026 1.00 21.39 ? 351 TRP B CD1 1 
ATOM   5988 C CD2 . TRP B 2 351 ? 171.775 179.260 188.178 1.00 21.39 ? 351 TRP B CD2 1 
ATOM   5989 N NE1 . TRP B 2 351 ? 170.617 180.386 189.718 1.00 21.39 ? 351 TRP B NE1 1 
ATOM   5990 C CE2 . TRP B 2 351 ? 171.875 180.198 189.212 1.00 21.39 ? 351 TRP B CE2 1 
ATOM   5991 C CE3 . TRP B 2 351 ? 172.931 178.889 187.494 1.00 21.39 ? 351 TRP B CE3 1 
ATOM   5992 C CZ2 . TRP B 2 351 ? 173.082 180.772 189.578 1.00 21.39 ? 351 TRP B CZ2 1 
ATOM   5993 C CZ3 . TRP B 2 351 ? 174.125 179.458 187.857 1.00 21.39 ? 351 TRP B CZ3 1 
ATOM   5994 C CH2 . TRP B 2 351 ? 174.194 180.388 188.888 1.00 21.39 ? 351 TRP B CH2 1 
ATOM   5995 N N   . SER B 2 352 ? 169.112 179.722 184.686 1.00 20.25 ? 352 SER B N   1 
ATOM   5996 C CA  . SER B 2 352 ? 169.447 180.992 184.058 1.00 20.25 ? 352 SER B CA  1 
ATOM   5997 C C   . SER B 2 352 ? 168.680 181.283 182.778 1.00 20.25 ? 352 SER B C   1 
ATOM   5998 O O   . SER B 2 352 ? 168.935 182.317 182.156 1.00 20.25 ? 352 SER B O   1 
ATOM   5999 C CB  . SER B 2 352 ? 170.946 181.050 183.755 1.00 20.25 ? 352 SER B CB  1 
ATOM   6000 O OG  . SER B 2 352 ? 171.286 180.116 182.750 1.00 20.25 ? 352 SER B OG  1 
ATOM   6001 N N   . LEU B 2 353 ? 167.763 180.416 182.353 1.00 17.53 ? 353 LEU B N   1 
ATOM   6002 C CA  . LEU B 2 353 ? 167.054 180.694 181.110 1.00 17.53 ? 353 LEU B CA  1 
ATOM   6003 C C   . LEU B 2 353 ? 166.137 181.915 181.188 1.00 17.53 ? 353 LEU B C   1 
ATOM   6004 O O   . LEU B 2 353 ? 166.122 182.716 180.242 1.00 17.53 ? 353 LEU B O   1 
ATOM   6005 C CB  . LEU B 2 353 ? 166.262 179.467 180.668 1.00 17.53 ? 353 LEU B CB  1 
ATOM   6006 C CG  . LEU B 2 353 ? 166.102 179.434 179.155 1.00 17.53 ? 353 LEU B CG  1 
ATOM   6007 C CD1 . LEU B 2 353 ? 167.459 179.249 178.514 1.00 17.53 ? 353 LEU B CD1 1 
ATOM   6008 C CD2 . LEU B 2 353 ? 165.175 178.326 178.751 1.00 17.53 ? 353 LEU B CD2 1 
ATOM   6009 N N   . PRO B 2 354 ? 165.334 182.092 182.249 1.00 16.53 ? 354 PRO B N   1 
ATOM   6010 C CA  . PRO B 2 354 ? 164.515 183.314 182.317 1.00 16.53 ? 354 PRO B CA  1 
ATOM   6011 C C   . PRO B 2 354 ? 165.334 184.589 182.249 1.00 16.53 ? 354 PRO B C   1 
ATOM   6012 O O   . PRO B 2 354 ? 164.918 185.559 181.603 1.00 16.53 ? 354 PRO B O   1 
ATOM   6013 C CB  . PRO B 2 354 ? 163.791 183.172 183.660 1.00 16.53 ? 354 PRO B CB  1 
ATOM   6014 C CG  . PRO B 2 354 ? 163.731 181.721 183.894 1.00 16.53 ? 354 PRO B CG  1 
ATOM   6015 C CD  . PRO B 2 354 ? 165.011 181.172 183.355 1.00 16.53 ? 354 PRO B CD  1 
ATOM   6016 N N   . PHE B 2 355 ? 166.502 184.607 182.890 1.00 9.46  ? 355 PHE B N   1 
ATOM   6017 C CA  . PHE B 2 355 ? 167.370 185.775 182.812 1.00 9.46  ? 355 PHE B CA  1 
ATOM   6018 C C   . PHE B 2 355 ? 167.858 186.003 181.388 1.00 9.46  ? 355 PHE B C   1 
ATOM   6019 O O   . PHE B 2 355 ? 167.916 187.146 180.916 1.00 9.46  ? 355 PHE B O   1 
ATOM   6020 C CB  . PHE B 2 355 ? 168.545 185.598 183.763 1.00 9.46  ? 355 PHE B CB  1 
ATOM   6021 C CG  . PHE B 2 355 ? 169.345 186.835 183.973 1.00 9.46  ? 355 PHE B CG  1 
ATOM   6022 C CD1 . PHE B 2 355 ? 168.897 187.821 184.820 1.00 9.46  ? 355 PHE B CD1 1 
ATOM   6023 C CD2 . PHE B 2 355 ? 170.555 187.000 183.340 1.00 9.46  ? 355 PHE B CD2 1 
ATOM   6024 C CE1 . PHE B 2 355 ? 169.636 188.953 185.024 1.00 9.46  ? 355 PHE B CE1 1 
ATOM   6025 C CE2 . PHE B 2 355 ? 171.300 188.131 183.540 1.00 9.46  ? 355 PHE B CE2 1 
ATOM   6026 C CZ  . PHE B 2 355 ? 170.841 189.108 184.382 1.00 9.46  ? 355 PHE B CZ  1 
ATOM   6027 N N   . VAL B 2 356 ? 168.217 184.925 180.690 1.00 12.16 ? 356 VAL B N   1 
ATOM   6028 C CA  . VAL B 2 356 ? 168.646 185.044 179.300 1.00 12.16 ? 356 VAL B CA  1 
ATOM   6029 C C   . VAL B 2 356 ? 167.541 185.667 178.461 1.00 12.16 ? 356 VAL B C   1 
ATOM   6030 O O   . VAL B 2 356 ? 167.774 186.610 177.692 1.00 12.16 ? 356 VAL B O   1 
ATOM   6031 C CB  . VAL B 2 356 ? 169.057 183.667 178.751 1.00 12.16 ? 356 VAL B CB  1 
ATOM   6032 C CG1 . VAL B 2 356 ? 169.056 183.679 177.241 1.00 12.16 ? 356 VAL B CG1 1 
ATOM   6033 C CG2 . VAL B 2 356 ? 170.417 183.275 179.278 1.00 12.16 ? 356 VAL B CG2 1 
ATOM   6034 N N   . GLY B 2 357 ? 166.320 185.150 178.602 1.00 12.06 ? 357 GLY B N   1 
ATOM   6035 C CA  . GLY B 2 357 ? 165.210 185.693 177.838 1.00 12.06 ? 357 GLY B CA  1 
ATOM   6036 C C   . GLY B 2 357 ? 164.958 187.155 178.144 1.00 12.06 ? 357 GLY B C   1 
ATOM   6037 O O   . GLY B 2 357 ? 164.738 187.961 177.235 1.00 12.06 ? 357 GLY B O   1 
ATOM   6038 N N   . GLU B 2 358 ? 165.010 187.521 179.425 1.00 12.85 ? 358 GLU B N   1 
ATOM   6039 C CA  . GLU B 2 358 ? 164.760 188.905 179.806 1.00 12.85 ? 358 GLU B CA  1 
ATOM   6040 C C   . GLU B 2 358 ? 165.811 189.842 179.225 1.00 12.85 ? 358 GLU B C   1 
ATOM   6041 O O   . GLU B 2 358 ? 165.475 190.912 178.701 1.00 12.85 ? 358 GLU B O   1 
ATOM   6042 C CB  . GLU B 2 358 ? 164.712 189.028 181.324 1.00 12.85 ? 358 GLU B CB  1 
ATOM   6043 C CG  . GLU B 2 358 ? 164.585 190.446 181.818 1.00 12.85 ? 358 GLU B CG  1 
ATOM   6044 C CD  . GLU B 2 358 ? 164.718 190.546 183.321 1.00 12.85 ? 358 GLU B CD  1 
ATOM   6045 O OE1 . GLU B 2 358 ? 164.806 189.491 183.982 1.00 12.85 ? 358 GLU B OE1 1 
ATOM   6046 O OE2 . GLU B 2 358 ? 164.734 191.679 183.843 1.00 12.85 ? 358 GLU B OE2 1 
ATOM   6047 N N   . LYS B 2 359 ? 167.087 189.458 179.289 1.00 9.38  ? 359 LYS B N   1 
ATOM   6048 C CA  . LYS B 2 359 ? 168.130 190.341 178.774 1.00 9.38  ? 359 LYS B CA  1 
ATOM   6049 C C   . LYS B 2 359 ? 168.063 190.467 177.254 1.00 9.38  ? 359 LYS B C   1 
ATOM   6050 O O   . LYS B 2 359 ? 168.231 191.568 176.710 1.00 9.38  ? 359 LYS B O   1 
ATOM   6051 C CB  . LYS B 2 359 ? 169.504 189.853 179.218 1.00 9.38  ? 359 LYS B CB  1 
ATOM   6052 C CG  . LYS B 2 359 ? 169.837 190.208 180.649 1.00 9.38  ? 359 LYS B CG  1 
ATOM   6053 C CD  . LYS B 2 359 ? 169.412 191.624 180.972 1.00 9.38  ? 359 LYS B CD  1 
ATOM   6054 C CE  . LYS B 2 359 ? 169.718 191.981 182.411 1.00 9.38  ? 359 LYS B CE  1 
ATOM   6055 N NZ  . LYS B 2 359 ? 169.150 193.300 182.787 1.00 9.38  ? 359 LYS B NZ  1 
ATOM   6056 N N   . VAL B 2 360 ? 167.815 189.359 176.548 1.00 9.40  ? 360 VAL B N   1 
ATOM   6057 C CA  . VAL B 2 360 ? 167.686 189.430 175.094 1.00 9.40  ? 360 VAL B CA  1 
ATOM   6058 C C   . VAL B 2 360 ? 166.536 190.352 174.712 1.00 9.40  ? 360 VAL B C   1 
ATOM   6059 O O   . VAL B 2 360 ? 166.675 191.230 173.847 1.00 9.40  ? 360 VAL B O   1 
ATOM   6060 C CB  . VAL B 2 360 ? 167.491 188.027 174.496 1.00 9.40  ? 360 VAL B CB  1 
ATOM   6061 C CG1 . VAL B 2 360 ? 167.168 188.133 173.033 1.00 9.40  ? 360 VAL B CG1 1 
ATOM   6062 C CG2 . VAL B 2 360 ? 168.724 187.194 174.677 1.00 9.40  ? 360 VAL B CG2 1 
ATOM   6063 N N   . THR B 2 361 ? 165.380 190.168 175.356 1.00 10.63 ? 361 THR B N   1 
ATOM   6064 C CA  . THR B 2 361 ? 164.219 190.984 175.027 1.00 10.63 ? 361 THR B CA  1 
ATOM   6065 C C   . THR B 2 361 ? 164.472 192.453 175.324 1.00 10.63 ? 361 THR B C   1 
ATOM   6066 O O   . THR B 2 361 ? 164.078 193.322 174.541 1.00 10.63 ? 361 THR B O   1 
ATOM   6067 C CB  . THR B 2 361 ? 162.996 190.486 175.789 1.00 10.63 ? 361 THR B CB  1 
ATOM   6068 O OG1 . THR B 2 361 ? 162.707 189.143 175.391 1.00 10.63 ? 361 THR B OG1 1 
ATOM   6069 C CG2 . THR B 2 361 ? 161.802 191.357 175.492 1.00 10.63 ? 361 THR B CG2 1 
ATOM   6070 N N   . GLU B 2 362 ? 165.133 192.756 176.446 1.00 12.58 ? 362 GLU B N   1 
ATOM   6071 C CA  . GLU B 2 362 ? 165.425 194.150 176.768 1.00 12.58 ? 362 GLU B CA  1 
ATOM   6072 C C   . GLU B 2 362 ? 166.336 194.781 175.720 1.00 12.58 ? 362 GLU B C   1 
ATOM   6073 O O   . GLU B 2 362 ? 166.066 195.886 175.226 1.00 12.58 ? 362 GLU B O   1 
ATOM   6074 C CB  . GLU B 2 362 ? 166.056 194.252 178.154 1.00 12.58 ? 362 GLU B CB  1 
ATOM   6075 C CG  . GLU B 2 362 ? 166.932 195.476 178.335 1.00 12.58 ? 362 GLU B CG  1 
ATOM   6076 C CD  . GLU B 2 362 ? 167.349 195.681 179.774 1.00 12.58 ? 362 GLU B CD  1 
ATOM   6077 O OE1 . GLU B 2 362 ? 166.727 195.072 180.666 1.00 12.58 ? 362 GLU B OE1 1 
ATOM   6078 O OE2 . GLU B 2 362 ? 168.305 196.446 180.014 1.00 12.58 ? 362 GLU B OE2 1 
ATOM   6079 N N   . MET B 2 363 ? 167.409 194.082 175.343 1.00 11.23 ? 363 MET B N   1 
ATOM   6080 C CA  . MET B 2 363 ? 168.328 194.672 174.376 1.00 11.23 ? 363 MET B CA  1 
ATOM   6081 C C   . MET B 2 363 ? 167.645 194.898 173.036 1.00 11.23 ? 363 MET B C   1 
ATOM   6082 O O   . MET B 2 363 ? 167.860 195.931 172.392 1.00 11.23 ? 363 MET B O   1 
ATOM   6083 C CB  . MET B 2 363 ? 169.561 193.801 174.190 1.00 11.23 ? 363 MET B CB  1 
ATOM   6084 C CG  . MET B 2 363 ? 170.556 194.405 173.219 1.00 11.23 ? 363 MET B CG  1 
ATOM   6085 S SD  . MET B 2 363 ? 170.576 193.618 171.612 1.00 11.23 ? 363 MET B SD  1 
ATOM   6086 C CE  . MET B 2 363 ? 170.786 191.930 172.125 1.00 11.23 ? 363 MET B CE  1 
ATOM   6087 N N   . LEU B 2 364 ? 166.813 193.950 172.595 1.00 8.42  ? 364 LEU B N   1 
ATOM   6088 C CA  . LEU B 2 364 ? 166.167 194.127 171.297 1.00 8.42  ? 364 LEU B CA  1 
ATOM   6089 C C   . LEU B 2 364 ? 165.098 195.212 171.331 1.00 8.42  ? 364 LEU B C   1 
ATOM   6090 O O   . LEU B 2 364 ? 165.014 196.024 170.404 1.00 8.42  ? 364 LEU B O   1 
ATOM   6091 C CB  . LEU B 2 364 ? 165.587 192.810 170.797 1.00 8.42  ? 364 LEU B CB  1 
ATOM   6092 C CG  . LEU B 2 364 ? 166.700 191.922 170.256 1.00 8.42  ? 364 LEU B CG  1 
ATOM   6093 C CD1 . LEU B 2 364 ? 166.152 190.611 169.796 1.00 8.42  ? 364 LEU B CD1 1 
ATOM   6094 C CD2 . LEU B 2 364 ? 167.414 192.625 169.125 1.00 8.42  ? 364 LEU B CD2 1 
ATOM   6095 N N   . VAL B 2 365 ? 164.270 195.257 172.377 1.00 10.05 ? 365 VAL B N   1 
ATOM   6096 C CA  . VAL B 2 365 ? 163.275 196.319 172.429 1.00 10.05 ? 365 VAL B CA  1 
ATOM   6097 C C   . VAL B 2 365 ? 163.928 197.675 172.613 1.00 10.05 ? 365 VAL B C   1 
ATOM   6098 O O   . VAL B 2 365 ? 163.271 198.700 172.414 1.00 10.05 ? 365 VAL B O   1 
ATOM   6099 C CB  . VAL B 2 365 ? 162.229 196.089 173.536 1.00 10.05 ? 365 VAL B CB  1 
ATOM   6100 C CG1 . VAL B 2 365 ? 161.550 194.747 173.365 1.00 10.05 ? 365 VAL B CG1 1 
ATOM   6101 C CG2 . VAL B 2 365 ? 162.853 196.215 174.907 1.00 10.05 ? 365 VAL B CG2 1 
ATOM   6102 N N   . ASN B 2 366 ? 165.203 197.719 172.997 1.00 10.97 ? 366 ASN B N   1 
ATOM   6103 C CA  . ASN B 2 366 ? 165.878 199.008 173.070 1.00 10.97 ? 366 ASN B CA  1 
ATOM   6104 C C   . ASN B 2 366 ? 166.577 199.385 171.763 1.00 10.97 ? 366 ASN B C   1 
ATOM   6105 O O   . ASN B 2 366 ? 166.594 200.566 171.399 1.00 10.97 ? 366 ASN B O   1 
ATOM   6106 C CB  . ASN B 2 366 ? 166.878 198.991 174.229 1.00 10.97 ? 366 ASN B CB  1 
ATOM   6107 C CG  . ASN B 2 366 ? 167.450 200.359 174.545 1.00 10.97 ? 366 ASN B CG  1 
ATOM   6108 O OD1 . ASN B 2 366 ? 167.945 200.619 175.638 1.00 10.97 ? 366 ASN B OD1 1 
ATOM   6109 N ND2 . ASN B 2 366 ? 167.392 201.247 173.564 1.00 10.97 ? 366 ASN B ND2 1 
ATOM   6110 N N   . VAL B 2 367 ? 167.134 198.416 171.029 1.00 11.83 ? 367 VAL B N   1 
ATOM   6111 C CA  . VAL B 2 367 ? 167.881 198.752 169.816 1.00 11.83 ? 367 VAL B CA  1 
ATOM   6112 C C   . VAL B 2 367 ? 166.945 199.195 168.695 1.00 11.83 ? 367 VAL B C   1 
ATOM   6113 O O   . VAL B 2 367 ? 167.283 200.087 167.910 1.00 11.83 ? 367 VAL B O   1 
ATOM   6114 C CB  . VAL B 2 367 ? 168.777 197.575 169.384 1.00 11.83 ? 367 VAL B CB  1 
ATOM   6115 C CG1 . VAL B 2 367 ? 167.957 196.422 168.855 1.00 11.83 ? 367 VAL B CG1 1 
ATOM   6116 C CG2 . VAL B 2 367 ? 169.765 198.031 168.340 1.00 11.83 ? 367 VAL B CG2 1 
ATOM   6117 N N   . LEU B 2 368 ? 165.761 198.587 168.595 1.00 13.64 ? 368 LEU B N   1 
ATOM   6118 C CA  . LEU B 2 368 ? 164.852 198.912 167.499 1.00 13.64 ? 368 LEU B CA  1 
ATOM   6119 C C   . LEU B 2 368 ? 164.387 200.361 167.548 1.00 13.64 ? 368 LEU B C   1 
ATOM   6120 O O   . LEU B 2 368 ? 164.119 200.955 166.499 1.00 13.64 ? 368 LEU B O   1 
ATOM   6121 C CB  . LEU B 2 368 ? 163.643 197.977 167.518 1.00 13.64 ? 368 LEU B CB  1 
ATOM   6122 C CG  . LEU B 2 368 ? 163.687 196.724 166.648 1.00 13.64 ? 368 LEU B CG  1 
ATOM   6123 C CD1 . LEU B 2 368 ? 164.697 195.739 167.169 1.00 13.64 ? 368 LEU B CD1 1 
ATOM   6124 C CD2 . LEU B 2 368 ? 162.320 196.092 166.609 1.00 13.64 ? 368 LEU B CD2 1 
ATOM   6125 N N   . ASN B 2 369 ? 164.273 200.942 168.737 1.00 15.93 ? 369 ASN B N   1 
ATOM   6126 C CA  . ASN B 2 369 ? 163.824 202.324 168.867 1.00 15.93 ? 369 ASN B CA  1 
ATOM   6127 C C   . ASN B 2 369 ? 164.375 202.978 170.129 1.00 15.93 ? 369 ASN B C   1 
ATOM   6128 O O   . ASN B 2 369 ? 165.457 203.565 170.111 1.00 15.93 ? 369 ASN B O   1 
ATOM   6129 C CB  . ASN B 2 369 ? 162.297 202.390 168.863 1.00 15.93 ? 369 ASN B CB  1 
ATOM   6130 C CG  . ASN B 2 369 ? 161.671 201.412 169.830 1.00 15.93 ? 369 ASN B CG  1 
ATOM   6131 O OD1 . ASN B 2 369 ? 162.356 200.807 170.649 1.00 15.93 ? 369 ASN B OD1 1 
ATOM   6132 N ND2 . ASN B 2 369 ? 160.360 201.241 169.732 1.00 15.93 ? 369 ASN B ND2 1 
ATOM   6133 N N   . GLY C 3 2   ? 152.540 196.350 200.210 1.00 16.55 ? 1   GLY C N   1 
ATOM   6134 C CA  . GLY C 3 2   ? 153.779 196.379 199.457 1.00 16.55 ? 1   GLY C CA  1 
ATOM   6135 C C   . GLY C 3 2   ? 154.944 195.742 200.187 1.00 16.55 ? 1   GLY C C   1 
ATOM   6136 O O   . GLY C 3 2   ? 155.015 194.521 200.308 1.00 16.55 ? 1   GLY C O   1 
ATOM   6137 N N   . VAL C 3 3   ? 155.861 196.574 200.674 1.00 16.15 ? 2   VAL C N   1 
ATOM   6138 C CA  . VAL C 3 3   ? 157.047 196.128 201.392 1.00 16.15 ? 2   VAL C CA  1 
ATOM   6139 C C   . VAL C 3 3   ? 157.155 196.910 202.693 1.00 16.15 ? 2   VAL C C   1 
ATOM   6140 O O   . VAL C 3 3   ? 156.918 198.122 202.720 1.00 16.15 ? 2   VAL C O   1 
ATOM   6141 C CB  . VAL C 3 3   ? 158.316 196.297 200.535 1.00 16.15 ? 2   VAL C CB  1 
ATOM   6142 C CG1 . VAL C 3 3   ? 158.472 197.736 200.106 1.00 16.15 ? 2   VAL C CG1 1 
ATOM   6143 C CG2 . VAL C 3 3   ? 159.525 195.861 201.311 1.00 16.15 ? 2   VAL C CG2 1 
ATOM   6144 N N   . GLN C 3 4   ? 157.488 196.212 203.779 1.00 18.16 ? 3   GLN C N   1 
ATOM   6145 C CA  . GLN C 3 4   ? 157.547 196.809 205.107 1.00 18.16 ? 3   GLN C CA  1 
ATOM   6146 C C   . GLN C 3 4   ? 158.797 196.330 205.826 1.00 18.16 ? 3   GLN C C   1 
ATOM   6147 O O   . GLN C 3 4   ? 159.038 195.124 205.915 1.00 18.16 ? 3   GLN C O   1 
ATOM   6148 C CB  . GLN C 3 4   ? 156.304 196.450 205.926 1.00 18.16 ? 3   GLN C CB  1 
ATOM   6149 C CG  . GLN C 3 4   ? 155.007 197.065 205.416 1.00 18.16 ? 3   GLN C CG  1 
ATOM   6150 C CD  . GLN C 3 4   ? 154.868 198.534 205.774 1.00 18.16 ? 3   GLN C CD  1 
ATOM   6151 O OE1 . GLN C 3 4   ? 154.853 198.899 206.949 1.00 18.16 ? 3   GLN C OE1 1 
ATOM   6152 N NE2 . GLN C 3 4   ? 154.759 199.384 204.760 1.00 18.16 ? 3   GLN C NE2 1 
ATOM   6153 N N   . VAL C 3 5   ? 159.575 197.269 206.354 1.00 25.63 ? 4   VAL C N   1 
ATOM   6154 C CA  . VAL C 3 5   ? 160.806 196.968 207.077 1.00 25.63 ? 4   VAL C CA  1 
ATOM   6155 C C   . VAL C 3 5   ? 160.528 197.115 208.566 1.00 25.63 ? 4   VAL C C   1 
ATOM   6156 O O   . VAL C 3 5   ? 160.116 198.188 209.027 1.00 25.63 ? 4   VAL C O   1 
ATOM   6157 C CB  . VAL C 3 5   ? 161.964 197.881 206.644 1.00 25.63 ? 4   VAL C CB  1 
ATOM   6158 C CG1 . VAL C 3 5   ? 163.121 197.780 207.625 1.00 25.63 ? 4   VAL C CG1 1 
ATOM   6159 C CG2 . VAL C 3 5   ? 162.429 197.526 205.246 1.00 25.63 ? 4   VAL C CG2 1 
ATOM   6160 N N   . GLU C 3 6   ? 160.750 196.038 209.318 1.00 27.69 ? 5   GLU C N   1 
ATOM   6161 C CA  . GLU C 3 6   ? 160.650 196.047 210.776 1.00 27.69 ? 5   GLU C CA  1 
ATOM   6162 C C   . GLU C 3 6   ? 161.975 195.523 211.323 1.00 27.69 ? 5   GLU C C   1 
ATOM   6163 O O   . GLU C 3 6   ? 162.200 194.312 211.384 1.00 27.69 ? 5   GLU C O   1 
ATOM   6164 C CB  . GLU C 3 6   ? 159.459 195.221 211.261 1.00 27.69 ? 5   GLU C CB  1 
ATOM   6165 C CG  . GLU C 3 6   ? 159.327 193.840 210.642 1.00 27.69 ? 5   GLU C CG  1 
ATOM   6166 C CD  . GLU C 3 6   ? 158.608 193.855 209.314 1.00 27.69 ? 5   GLU C CD  1 
ATOM   6167 O OE1 . GLU C 3 6   ? 158.506 194.935 208.698 1.00 27.69 ? 5   GLU C OE1 1 
ATOM   6168 O OE2 . GLU C 3 6   ? 158.146 192.779 208.885 1.00 27.69 ? 5   GLU C OE2 1 
ATOM   6169 N N   . THR C 3 7   ? 162.850 196.441 211.721 1.00 33.71 ? 6   THR C N   1 
ATOM   6170 C CA  . THR C 3 7   ? 164.207 196.067 212.089 1.00 33.71 ? 6   THR C CA  1 
ATOM   6171 C C   . THR C 3 7   ? 164.217 195.144 213.300 1.00 33.71 ? 6   THR C C   1 
ATOM   6172 O O   . THR C 3 7   ? 163.286 195.127 214.109 1.00 33.71 ? 6   THR C O   1 
ATOM   6173 C CB  . THR C 3 7   ? 165.047 197.312 212.378 1.00 33.71 ? 6   THR C CB  1 
ATOM   6174 O OG1 . THR C 3 7   ? 166.414 196.933 212.574 1.00 33.71 ? 6   THR C OG1 1 
ATOM   6175 C CG2 . THR C 3 7   ? 164.541 198.025 213.617 1.00 33.71 ? 6   THR C CG2 1 
ATOM   6176 N N   . ILE C 3 8   ? 165.275 194.350 213.397 1.00 39.26 ? 7   ILE C N   1 
ATOM   6177 C CA  . ILE C 3 8   ? 165.516 193.488 214.547 1.00 39.26 ? 7   ILE C CA  1 
ATOM   6178 C C   . ILE C 3 8   ? 166.675 194.003 215.388 1.00 39.26 ? 7   ILE C C   1 
ATOM   6179 O O   . ILE C 3 8   ? 166.554 194.153 216.603 1.00 39.26 ? 7   ILE C O   1 
ATOM   6180 C CB  . ILE C 3 8   ? 165.758 192.029 214.096 1.00 39.26 ? 7   ILE C CB  1 
ATOM   6181 C CG1 . ILE C 3 8   ? 164.524 191.453 213.400 1.00 39.26 ? 7   ILE C CG1 1 
ATOM   6182 C CG2 . ILE C 3 8   ? 166.144 191.159 215.276 1.00 39.26 ? 7   ILE C CG2 1 
ATOM   6183 C CD1 . ILE C 3 8   ? 164.480 191.692 211.919 1.00 39.26 ? 7   ILE C CD1 1 
ATOM   6184 N N   . SER C 3 9   ? 167.809 194.287 214.753 1.00 38.67 ? 8   SER C N   1 
ATOM   6185 C CA  . SER C 3 9   ? 169.003 194.780 215.437 1.00 38.67 ? 8   SER C CA  1 
ATOM   6186 C C   . SER C 3 9   ? 169.527 196.006 214.703 1.00 38.67 ? 8   SER C C   1 
ATOM   6187 O O   . SER C 3 9   ? 170.592 195.961 214.076 1.00 38.67 ? 8   SER C O   1 
ATOM   6188 C CB  . SER C 3 9   ? 170.069 193.689 215.517 1.00 38.67 ? 8   SER C CB  1 
ATOM   6189 O OG  . SER C 3 9   ? 170.248 193.073 214.255 1.00 38.67 ? 8   SER C OG  1 
ATOM   6190 N N   . PRO C 3 10  ? 168.806 197.125 214.773 1.00 42.70 ? 9   PRO C N   1 
ATOM   6191 C CA  . PRO C 3 10  ? 169.191 198.300 213.984 1.00 42.70 ? 9   PRO C CA  1 
ATOM   6192 C C   . PRO C 3 10  ? 170.566 198.822 214.368 1.00 42.70 ? 9   PRO C C   1 
ATOM   6193 O O   . PRO C 3 10  ? 170.986 198.751 215.524 1.00 42.70 ? 9   PRO C O   1 
ATOM   6194 C CB  . PRO C 3 10  ? 168.096 199.324 214.307 1.00 42.70 ? 9   PRO C CB  1 
ATOM   6195 C CG  . PRO C 3 10  ? 167.520 198.875 215.602 1.00 42.70 ? 9   PRO C CG  1 
ATOM   6196 C CD  . PRO C 3 10  ? 167.621 197.382 215.607 1.00 42.70 ? 9   PRO C CD  1 
ATOM   6197 N N   . GLY C 3 11  ? 171.270 199.346 213.369 1.00 48.41 ? 10  GLY C N   1 
ATOM   6198 C CA  . GLY C 3 11  ? 172.592 199.899 213.568 1.00 48.41 ? 10  GLY C CA  1 
ATOM   6199 C C   . GLY C 3 11  ? 172.651 201.379 213.257 1.00 48.41 ? 10  GLY C C   1 
ATOM   6200 O O   . GLY C 3 11  ? 171.651 202.087 213.398 1.00 48.41 ? 10  GLY C O   1 
ATOM   6201 N N   . ASP C 3 12  ? 173.816 201.856 212.827 1.00 55.17 ? 11  ASP C N   1 
ATOM   6202 C CA  . ASP C 3 12  ? 173.996 203.279 212.576 1.00 55.17 ? 11  ASP C CA  1 
ATOM   6203 C C   . ASP C 3 12  ? 173.131 203.733 211.408 1.00 55.17 ? 11  ASP C C   1 
ATOM   6204 O O   . ASP C 3 12  ? 173.098 203.089 210.355 1.00 55.17 ? 11  ASP C O   1 
ATOM   6205 C CB  . ASP C 3 12  ? 175.463 203.586 212.294 1.00 55.17 ? 11  ASP C CB  1 
ATOM   6206 C CG  . ASP C 3 12  ? 175.728 205.068 212.173 1.00 55.17 ? 11  ASP C CG  1 
ATOM   6207 O OD1 . ASP C 3 12  ? 175.760 205.756 213.214 1.00 55.17 ? 11  ASP C OD1 1 
ATOM   6208 O OD2 . ASP C 3 12  ? 175.897 205.548 211.034 1.00 55.17 ? 11  ASP C OD2 1 
ATOM   6209 N N   . GLY C 3 13  ? 172.429 204.850 211.599 1.00 56.84 ? 12  GLY C N   1 
ATOM   6210 C CA  . GLY C 3 13  ? 171.579 205.424 210.577 1.00 56.84 ? 12  GLY C CA  1 
ATOM   6211 C C   . GLY C 3 13  ? 172.108 206.667 209.896 1.00 56.84 ? 12  GLY C C   1 
ATOM   6212 O O   . GLY C 3 13  ? 171.333 207.366 209.236 1.00 56.84 ? 12  GLY C O   1 
ATOM   6213 N N   . ARG C 3 14  ? 173.397 206.977 210.034 1.00 58.85 ? 13  ARG C N   1 
ATOM   6214 C CA  . ARG C 3 14  ? 173.952 208.175 209.421 1.00 58.85 ? 13  ARG C CA  1 
ATOM   6215 C C   . ARG C 3 14  ? 174.348 207.971 207.965 1.00 58.85 ? 13  ARG C C   1 
ATOM   6216 O O   . ARG C 3 14  ? 174.765 208.936 207.316 1.00 58.85 ? 13  ARG C O   1 
ATOM   6217 C CB  . ARG C 3 14  ? 175.167 208.660 210.217 1.00 58.85 ? 13  ARG C CB  1 
ATOM   6218 N N   . THR C 3 15  ? 174.236 206.754 207.442 1.00 52.92 ? 14  THR C N   1 
ATOM   6219 C CA  . THR C 3 15  ? 174.587 206.452 206.061 1.00 52.92 ? 14  THR C CA  1 
ATOM   6220 C C   . THR C 3 15  ? 173.401 205.791 205.375 1.00 52.92 ? 14  THR C C   1 
ATOM   6221 O O   . THR C 3 15  ? 172.836 204.827 205.900 1.00 52.92 ? 14  THR C O   1 
ATOM   6222 C CB  . THR C 3 15  ? 175.816 205.542 205.994 1.00 52.92 ? 14  THR C CB  1 
ATOM   6223 O OG1 . THR C 3 15  ? 176.926 206.190 206.623 1.00 52.92 ? 14  THR C OG1 1 
ATOM   6224 C CG2 . THR C 3 15  ? 176.173 205.232 204.552 1.00 52.92 ? 14  THR C CG2 1 
ATOM   6225 N N   . PHE C 3 16  ? 173.036 206.300 204.201 1.00 57.99 ? 15  PHE C N   1 
ATOM   6226 C CA  . PHE C 3 16  ? 171.911 205.781 203.442 1.00 57.99 ? 15  PHE C CA  1 
ATOM   6227 C C   . PHE C 3 16  ? 172.352 205.393 202.036 1.00 57.99 ? 15  PHE C C   1 
ATOM   6228 O O   . PHE C 3 16  ? 173.302 205.969 201.498 1.00 57.99 ? 15  PHE C O   1 
ATOM   6229 C CB  . PHE C 3 16  ? 170.775 206.810 203.357 1.00 57.99 ? 15  PHE C CB  1 
ATOM   6230 C CG  . PHE C 3 16  ? 169.920 206.875 204.591 1.00 57.99 ? 15  PHE C CG  1 
ATOM   6231 C CD1 . PHE C 3 16  ? 168.875 205.983 204.770 1.00 57.99 ? 15  PHE C CD1 1 
ATOM   6232 C CD2 . PHE C 3 16  ? 170.161 207.821 205.572 1.00 57.99 ? 15  PHE C CD2 1 
ATOM   6233 C CE1 . PHE C 3 16  ? 168.088 206.034 205.900 1.00 57.99 ? 15  PHE C CE1 1 
ATOM   6234 C CE2 . PHE C 3 16  ? 169.375 207.877 206.706 1.00 57.99 ? 15  PHE C CE2 1 
ATOM   6235 C CZ  . PHE C 3 16  ? 168.337 206.981 206.869 1.00 57.99 ? 15  PHE C CZ  1 
ATOM   6236 N N   . PRO C 3 17  ? 171.685 204.417 201.416 1.00 49.63 ? 16  PRO C N   1 
ATOM   6237 C CA  . PRO C 3 17  ? 172.111 203.962 200.086 1.00 49.63 ? 16  PRO C CA  1 
ATOM   6238 C C   . PRO C 3 17  ? 171.733 204.968 199.008 1.00 49.63 ? 16  PRO C C   1 
ATOM   6239 O O   . PRO C 3 17  ? 170.557 205.288 198.819 1.00 49.63 ? 16  PRO C O   1 
ATOM   6240 C CB  . PRO C 3 17  ? 171.360 202.638 199.903 1.00 49.63 ? 16  PRO C CB  1 
ATOM   6241 C CG  . PRO C 3 17  ? 170.176 202.747 200.785 1.00 49.63 ? 16  PRO C CG  1 
ATOM   6242 C CD  . PRO C 3 17  ? 170.555 203.629 201.938 1.00 49.63 ? 16  PRO C CD  1 
ATOM   6243 N N   . LYS C 3 18  ? 172.744 205.465 198.300 1.00 56.37 ? 17  LYS C N   1 
ATOM   6244 C CA  . LYS C 3 18  ? 172.524 206.345 197.166 1.00 56.37 ? 17  LYS C CA  1 
ATOM   6245 C C   . LYS C 3 18  ? 172.005 205.541 195.978 1.00 56.37 ? 17  LYS C C   1 
ATOM   6246 O O   . LYS C 3 18  ? 171.979 204.308 195.990 1.00 56.37 ? 17  LYS C O   1 
ATOM   6247 C CB  . LYS C 3 18  ? 173.814 207.071 196.784 1.00 56.37 ? 17  LYS C CB  1 
ATOM   6248 C CG  . LYS C 3 18  ? 174.629 207.594 197.960 1.00 56.37 ? 17  LYS C CG  1 
ATOM   6249 C CD  . LYS C 3 18  ? 173.817 208.505 198.864 1.00 56.37 ? 17  LYS C CD  1 
ATOM   6250 C CE  . LYS C 3 18  ? 174.684 209.095 199.966 1.00 56.37 ? 17  LYS C CE  1 
ATOM   6251 N NZ  . LYS C 3 18  ? 173.892 209.918 200.921 1.00 56.37 ? 17  LYS C NZ  1 
ATOM   6252 N N   . ARG C 3 19  ? 171.583 206.255 194.936 1.00 54.05 ? 18  ARG C N   1 
ATOM   6253 C CA  . ARG C 3 19  ? 171.096 205.569 193.745 1.00 54.05 ? 18  ARG C CA  1 
ATOM   6254 C C   . ARG C 3 19  ? 172.240 204.985 192.922 1.00 54.05 ? 18  ARG C C   1 
ATOM   6255 O O   . ARG C 3 19  ? 172.053 203.980 192.229 1.00 54.05 ? 18  ARG C O   1 
ATOM   6256 C CB  . ARG C 3 19  ? 170.253 206.518 192.892 1.00 54.05 ? 18  ARG C CB  1 
ATOM   6257 C CG  . ARG C 3 19  ? 169.283 205.806 191.964 1.00 54.05 ? 18  ARG C CG  1 
ATOM   6258 C CD  . ARG C 3 19  ? 168.575 206.777 191.036 1.00 54.05 ? 18  ARG C CD  1 
ATOM   6259 N NE  . ARG C 3 19  ? 167.839 207.805 191.767 1.00 54.05 ? 18  ARG C NE  1 
ATOM   6260 C CZ  . ARG C 3 19  ? 167.303 208.883 191.203 1.00 54.05 ? 18  ARG C CZ  1 
ATOM   6261 N NH1 . ARG C 3 19  ? 167.418 209.080 189.897 1.00 54.05 ? 18  ARG C NH1 1 
ATOM   6262 N NH2 . ARG C 3 19  ? 166.648 209.766 191.946 1.00 54.05 ? 18  ARG C NH2 1 
ATOM   6263 N N   . GLY C 3 20  ? 173.424 205.587 192.988 1.00 52.60 ? 19  GLY C N   1 
ATOM   6264 C CA  . GLY C 3 20  ? 174.518 205.162 192.138 1.00 52.60 ? 19  GLY C CA  1 
ATOM   6265 C C   . GLY C 3 20  ? 175.530 204.249 192.798 1.00 52.60 ? 19  GLY C C   1 
ATOM   6266 O O   . GLY C 3 20  ? 176.652 204.108 192.305 1.00 52.60 ? 19  GLY C O   1 
ATOM   6267 N N   . GLN C 3 21  ? 175.158 203.624 193.908 1.00 42.49 ? 20  GLN C N   1 
ATOM   6268 C CA  . GLN C 3 21  ? 176.069 202.777 194.663 1.00 42.49 ? 20  GLN C CA  1 
ATOM   6269 C C   . GLN C 3 21  ? 175.639 201.320 194.573 1.00 42.49 ? 20  GLN C C   1 
ATOM   6270 O O   . GLN C 3 21  ? 174.546 200.992 194.105 1.00 42.49 ? 20  GLN C O   1 
ATOM   6271 C CB  . GLN C 3 21  ? 176.132 203.223 196.127 1.00 42.49 ? 20  GLN C CB  1 
ATOM   6272 C CG  . GLN C 3 21  ? 176.902 204.510 196.350 1.00 42.49 ? 20  GLN C CG  1 
ATOM   6273 C CD  . GLN C 3 21  ? 177.327 204.689 197.791 1.00 42.49 ? 20  GLN C CD  1 
ATOM   6274 O OE1 . GLN C 3 21  ? 176.510 205.001 198.656 1.00 42.49 ? 20  GLN C OE1 1 
ATOM   6275 N NE2 . GLN C 3 21  ? 178.612 204.499 198.057 1.00 42.49 ? 20  GLN C NE2 1 
ATOM   6276 N N   . THR C 3 22  ? 176.523 200.440 195.032 1.00 32.01 ? 21  THR C N   1 
ATOM   6277 C CA  . THR C 3 22  ? 176.255 199.011 195.104 1.00 32.01 ? 21  THR C CA  1 
ATOM   6278 C C   . THR C 3 22  ? 176.196 198.579 196.564 1.00 32.01 ? 21  THR C C   1 
ATOM   6279 O O   . THR C 3 22  ? 177.076 198.924 197.361 1.00 32.01 ? 21  THR C O   1 
ATOM   6280 C CB  . THR C 3 22  ? 177.308 198.207 194.330 1.00 32.01 ? 21  THR C CB  1 
ATOM   6281 O OG1 . THR C 3 22  ? 176.931 196.826 194.298 1.00 32.01 ? 21  THR C OG1 1 
ATOM   6282 C CG2 . THR C 3 22  ? 178.696 198.349 194.940 1.00 32.01 ? 21  THR C CG2 1 
ATOM   6283 N N   . CYS C 3 23  ? 175.142 197.852 196.914 1.00 24.57 ? 22  CYS C N   1 
ATOM   6284 C CA  . CYS C 3 23  ? 174.908 197.397 198.274 1.00 24.57 ? 22  CYS C CA  1 
ATOM   6285 C C   . CYS C 3 23  ? 175.220 195.912 198.384 1.00 24.57 ? 22  CYS C C   1 
ATOM   6286 O O   . CYS C 3 23  ? 174.861 195.122 197.501 1.00 24.57 ? 22  CYS C O   1 
ATOM   6287 C CB  . CYS C 3 23  ? 173.463 197.665 198.699 1.00 24.57 ? 22  CYS C CB  1 
ATOM   6288 S SG  . CYS C 3 23  ? 172.959 199.390 198.541 1.00 24.57 ? 22  CYS C SG  1 
ATOM   6289 N N   . VAL C 3 24  ? 175.899 195.545 199.468 1.00 20.85 ? 23  VAL C N   1 
ATOM   6290 C CA  . VAL C 3 24  ? 176.286 194.169 199.750 1.00 20.85 ? 23  VAL C CA  1 
ATOM   6291 C C   . VAL C 3 24  ? 175.481 193.685 200.948 1.00 20.85 ? 23  VAL C C   1 
ATOM   6292 O O   . VAL C 3 24  ? 175.451 194.345 201.993 1.00 20.85 ? 23  VAL C O   1 
ATOM   6293 C CB  . VAL C 3 24  ? 177.800 194.056 200.001 1.00 20.85 ? 23  VAL C CB  1 
ATOM   6294 C CG1 . VAL C 3 24  ? 178.557 194.378 198.737 1.00 20.85 ? 23  VAL C CG1 1 
ATOM   6295 C CG2 . VAL C 3 24  ? 178.236 195.003 201.093 1.00 20.85 ? 23  VAL C CG2 1 
ATOM   6296 N N   . VAL C 3 25  ? 174.811 192.547 200.792 1.00 18.79 ? 24  VAL C N   1 
ATOM   6297 C CA  . VAL C 3 25  ? 173.877 192.057 201.797 1.00 18.79 ? 24  VAL C CA  1 
ATOM   6298 C C   . VAL C 3 25  ? 173.994 190.547 201.924 1.00 18.79 ? 24  VAL C C   1 
ATOM   6299 O O   . VAL C 3 25  ? 174.357 189.850 200.973 1.00 18.79 ? 24  VAL C O   1 
ATOM   6300 C CB  . VAL C 3 25  ? 172.425 192.442 201.459 1.00 18.79 ? 24  VAL C CB  1 
ATOM   6301 C CG1 . VAL C 3 25  ? 172.193 193.913 201.708 1.00 18.79 ? 24  VAL C CG1 1 
ATOM   6302 C CG2 . VAL C 3 25  ? 172.125 192.100 200.023 1.00 18.79 ? 24  VAL C CG2 1 
ATOM   6303 N N   . HIS C 3 26  ? 173.686 190.046 203.123 1.00 17.86 ? 25  HIS C N   1 
ATOM   6304 C CA  . HIS C 3 26  ? 173.565 188.613 203.386 1.00 17.86 ? 25  HIS C CA  1 
ATOM   6305 C C   . HIS C 3 26  ? 172.087 188.272 203.551 1.00 17.86 ? 25  HIS C C   1 
ATOM   6306 O O   . HIS C 3 26  ? 171.563 188.188 204.658 1.00 17.86 ? 25  HIS C O   1 
ATOM   6307 C CB  . HIS C 3 26  ? 174.353 188.226 204.631 1.00 17.86 ? 25  HIS C CB  1 
ATOM   6308 C CG  . HIS C 3 26  ? 175.782 187.878 204.369 1.00 17.86 ? 25  HIS C CG  1 
ATOM   6309 N ND1 . HIS C 3 26  ? 176.826 188.691 204.749 1.00 17.86 ? 25  HIS C ND1 1 
ATOM   6310 C CD2 . HIS C 3 26  ? 176.341 186.795 203.781 1.00 17.86 ? 25  HIS C CD2 1 
ATOM   6311 C CE1 . HIS C 3 26  ? 177.968 188.127 204.400 1.00 17.86 ? 25  HIS C CE1 1 
ATOM   6312 N NE2 . HIS C 3 26  ? 177.702 186.977 203.810 1.00 17.86 ? 25  HIS C NE2 1 
ATOM   6313 N N   . TYR C 3 27  ? 171.412 188.051 202.433 1.00 21.39 ? 26  TYR C N   1 
ATOM   6314 C CA  . TYR C 3 27  ? 169.990 187.755 202.482 1.00 21.39 ? 26  TYR C CA  1 
ATOM   6315 C C   . TYR C 3 27  ? 169.762 186.289 202.816 1.00 21.39 ? 26  TYR C C   1 
ATOM   6316 O O   . TYR C 3 27  ? 170.499 185.416 202.357 1.00 21.39 ? 26  TYR C O   1 
ATOM   6317 C CB  . TYR C 3 27  ? 169.325 188.101 201.153 1.00 21.39 ? 26  TYR C CB  1 
ATOM   6318 C CG  . TYR C 3 27  ? 169.541 187.089 200.061 1.00 21.39 ? 26  TYR C CG  1 
ATOM   6319 C CD1 . TYR C 3 27  ? 170.710 187.069 199.328 1.00 21.39 ? 26  TYR C CD1 1 
ATOM   6320 C CD2 . TYR C 3 27  ? 168.566 186.161 199.755 1.00 21.39 ? 26  TYR C CD2 1 
ATOM   6321 C CE1 . TYR C 3 27  ? 170.902 186.150 198.329 1.00 21.39 ? 26  TYR C CE1 1 
ATOM   6322 C CE2 . TYR C 3 27  ? 168.752 185.243 198.761 1.00 21.39 ? 26  TYR C CE2 1 
ATOM   6323 C CZ  . TYR C 3 27  ? 169.918 185.240 198.050 1.00 21.39 ? 26  TYR C CZ  1 
ATOM   6324 O OH  . TYR C 3 27  ? 170.096 184.313 197.057 1.00 21.39 ? 26  TYR C OH  1 
ATOM   6325 N N   . THR C 3 28  ? 168.743 186.021 203.632 1.00 15.52 ? 27  THR C N   1 
ATOM   6326 C CA  . THR C 3 28  ? 168.348 184.658 203.992 1.00 15.52 ? 27  THR C CA  1 
ATOM   6327 C C   . THR C 3 28  ? 166.837 184.547 203.819 1.00 15.52 ? 27  THR C C   1 
ATOM   6328 O O   . THR C 3 28  ? 166.086 184.690 204.783 1.00 15.52 ? 27  THR C O   1 
ATOM   6329 C CB  . THR C 3 28  ? 168.775 184.330 205.415 1.00 15.52 ? 27  THR C CB  1 
ATOM   6330 O OG1 . THR C 3 28  ? 170.161 184.649 205.583 1.00 15.52 ? 27  THR C OG1 1 
ATOM   6331 C CG2 . THR C 3 28  ? 168.566 182.860 205.711 1.00 15.52 ? 27  THR C CG2 1 
ATOM   6332 N N   . GLY C 3 29  ? 166.393 184.265 202.600 1.00 11.45 ? 28  GLY C N   1 
ATOM   6333 C CA  . GLY C 3 29  ? 164.981 184.349 202.300 1.00 11.45 ? 28  GLY C CA  1 
ATOM   6334 C C   . GLY C 3 29  ? 164.220 183.096 202.675 1.00 11.45 ? 28  GLY C C   1 
ATOM   6335 O O   . GLY C 3 29  ? 164.776 182.010 202.803 1.00 11.45 ? 28  GLY C O   1 
ATOM   6336 N N   . MET C 3 30  ? 162.913 183.264 202.864 1.00 15.62 ? 29  MET C N   1 
ATOM   6337 C CA  . MET C 3 30  ? 161.997 182.151 203.097 1.00 15.62 ? 29  MET C CA  1 
ATOM   6338 C C   . MET C 3 30  ? 160.705 182.430 202.342 1.00 15.62 ? 29  MET C C   1 
ATOM   6339 O O   . MET C 3 30  ? 160.596 183.411 201.604 1.00 15.62 ? 29  MET C O   1 
ATOM   6340 C CB  . MET C 3 30  ? 161.711 181.946 204.590 1.00 15.62 ? 29  MET C CB  1 
ATOM   6341 C CG  . MET C 3 30  ? 162.889 182.139 205.515 1.00 15.62 ? 29  MET C CG  1 
ATOM   6342 S SD  . MET C 3 30  ? 162.381 182.294 207.232 1.00 15.62 ? 29  MET C SD  1 
ATOM   6343 C CE  . MET C 3 30  ? 163.717 183.290 207.877 1.00 15.62 ? 29  MET C CE  1 
ATOM   6344 N N   . LEU C 3 31  ? 159.719 181.565 202.527 1.00 12.13 ? 30  LEU C N   1 
ATOM   6345 C CA  . LEU C 3 31  ? 158.357 181.844 202.116 1.00 12.13 ? 30  LEU C CA  1 
ATOM   6346 C C   . LEU C 3 31  ? 157.625 182.450 203.307 1.00 12.13 ? 30  LEU C C   1 
ATOM   6347 O O   . LEU C 3 31  ? 158.231 182.747 204.341 1.00 12.13 ? 30  LEU C O   1 
ATOM   6348 C CB  . LEU C 3 31  ? 157.673 180.578 201.600 1.00 12.13 ? 30  LEU C CB  1 
ATOM   6349 C CG  . LEU C 3 31  ? 157.679 180.341 200.089 1.00 12.13 ? 30  LEU C CG  1 
ATOM   6350 C CD1 . LEU C 3 31  ? 159.066 179.982 199.611 1.00 12.13 ? 30  LEU C CD1 1 
ATOM   6351 C CD2 . LEU C 3 31  ? 156.690 179.259 199.703 1.00 12.13 ? 30  LEU C CD2 1 
ATOM   6352 N N   . GLU C 3 32  ? 156.312 182.635 203.170 1.00 20.50 ? 31  GLU C N   1 
ATOM   6353 C CA  . GLU C 3 32  ? 155.560 183.272 204.246 1.00 20.50 ? 31  GLU C CA  1 
ATOM   6354 C C   . GLU C 3 32  ? 155.534 182.414 205.504 1.00 20.50 ? 31  GLU C C   1 
ATOM   6355 O O   . GLU C 3 32  ? 155.432 182.949 206.614 1.00 20.50 ? 31  GLU C O   1 
ATOM   6356 C CB  . GLU C 3 32  ? 154.137 183.589 203.785 1.00 20.50 ? 31  GLU C CB  1 
ATOM   6357 C CG  . GLU C 3 32  ? 153.327 182.387 203.353 1.00 20.50 ? 31  GLU C CG  1 
ATOM   6358 C CD  . GLU C 3 32  ? 153.550 182.026 201.900 1.00 20.50 ? 31  GLU C CD  1 
ATOM   6359 O OE1 . GLU C 3 32  ? 154.710 182.073 201.445 1.00 20.50 ? 31  GLU C OE1 1 
ATOM   6360 O OE2 . GLU C 3 32  ? 152.565 181.695 201.210 1.00 20.50 ? 31  GLU C OE2 1 
ATOM   6361 N N   . ASP C 3 33  ? 155.641 181.093 205.361 1.00 21.54 ? 32  ASP C N   1 
ATOM   6362 C CA  . ASP C 3 33  ? 155.551 180.175 206.489 1.00 21.54 ? 32  ASP C CA  1 
ATOM   6363 C C   . ASP C 3 33  ? 156.913 179.780 207.048 1.00 21.54 ? 32  ASP C C   1 
ATOM   6364 O O   . ASP C 3 33  ? 156.988 178.876 207.883 1.00 21.54 ? 32  ASP C O   1 
ATOM   6365 C CB  . ASP C 3 33  ? 154.751 178.928 206.093 1.00 21.54 ? 32  ASP C CB  1 
ATOM   6366 C CG  . ASP C 3 33  ? 155.293 178.244 204.851 1.00 21.54 ? 32  ASP C CG  1 
ATOM   6367 O OD1 . ASP C 3 33  ? 156.524 178.228 204.651 1.00 21.54 ? 32  ASP C OD1 1 
ATOM   6368 O OD2 . ASP C 3 33  ? 154.478 177.721 204.063 1.00 21.54 ? 32  ASP C OD2 1 
ATOM   6369 N N   . GLY C 3 34  ? 157.986 180.430 206.606 1.00 19.55 ? 33  GLY C N   1 
ATOM   6370 C CA  . GLY C 3 34  ? 159.309 180.175 207.134 1.00 19.55 ? 33  GLY C CA  1 
ATOM   6371 C C   . GLY C 3 34  ? 160.083 179.057 206.471 1.00 19.55 ? 33  GLY C C   1 
ATOM   6372 O O   . GLY C 3 34  ? 161.193 178.748 206.922 1.00 19.55 ? 33  GLY C O   1 
ATOM   6373 N N   . LYS C 3 35  ? 159.548 178.444 205.417 1.00 16.11 ? 34  LYS C N   1 
ATOM   6374 C CA  . LYS C 3 35  ? 160.245 177.374 204.703 1.00 16.11 ? 34  LYS C CA  1 
ATOM   6375 C C   . LYS C 3 35  ? 161.364 177.984 203.870 1.00 16.11 ? 34  LYS C C   1 
ATOM   6376 O O   . LYS C 3 35  ? 161.122 178.548 202.803 1.00 16.11 ? 34  LYS C O   1 
ATOM   6377 C CB  . LYS C 3 35  ? 159.268 176.602 203.825 1.00 16.11 ? 34  LYS C CB  1 
ATOM   6378 C CG  . LYS C 3 35  ? 159.928 175.587 202.914 1.00 16.11 ? 34  LYS C CG  1 
ATOM   6379 C CD  . LYS C 3 35  ? 158.959 175.073 201.866 1.00 16.11 ? 34  LYS C CD  1 
ATOM   6380 C CE  . LYS C 3 35  ? 159.411 173.738 201.304 1.00 16.11 ? 34  LYS C CE  1 
ATOM   6381 N NZ  . LYS C 3 35  ? 160.728 173.830 200.621 1.00 16.11 ? 34  LYS C NZ  1 
ATOM   6382 N N   . LYS C 3 36  ? 162.599 177.868 204.351 1.00 11.41 ? 35  LYS C N   1 
ATOM   6383 C CA  . LYS C 3 36  ? 163.722 178.534 203.704 1.00 11.41 ? 35  LYS C CA  1 
ATOM   6384 C C   . LYS C 3 36  ? 163.983 177.935 202.331 1.00 11.41 ? 35  LYS C C   1 
ATOM   6385 O O   . LYS C 3 36  ? 164.072 176.713 202.183 1.00 11.41 ? 35  LYS C O   1 
ATOM   6386 C CB  . LYS C 3 36  ? 164.972 178.424 204.571 1.00 11.41 ? 35  LYS C CB  1 
ATOM   6387 C CG  . LYS C 3 36  ? 166.156 179.196 204.038 1.00 11.41 ? 35  LYS C CG  1 
ATOM   6388 C CD  . LYS C 3 36  ? 167.234 179.350 205.093 1.00 11.41 ? 35  LYS C CD  1 
ATOM   6389 C CE  . LYS C 3 36  ? 168.124 178.129 205.164 1.00 11.41 ? 35  LYS C CE  1 
ATOM   6390 N NZ  . LYS C 3 36  ? 169.042 178.039 204.000 1.00 11.41 ? 35  LYS C NZ  1 
ATOM   6391 N N   . PHE C 3 37  ? 164.115 178.799 201.322 1.00 14.84 ? 36  PHE C N   1 
ATOM   6392 C CA  . PHE C 3 37  ? 164.387 178.355 199.963 1.00 14.84 ? 36  PHE C CA  1 
ATOM   6393 C C   . PHE C 3 37  ? 165.742 178.792 199.429 1.00 14.84 ? 36  PHE C C   1 
ATOM   6394 O O   . PHE C 3 37  ? 166.233 178.177 198.479 1.00 14.84 ? 36  PHE C O   1 
ATOM   6395 C CB  . PHE C 3 37  ? 163.281 178.836 199.006 1.00 14.84 ? 36  PHE C CB  1 
ATOM   6396 C CG  . PHE C 3 37  ? 163.257 180.326 198.772 1.00 14.84 ? 36  PHE C CG  1 
ATOM   6397 C CD1 . PHE C 3 37  ? 162.356 181.128 199.444 1.00 14.84 ? 36  PHE C CD1 1 
ATOM   6398 C CD2 . PHE C 3 37  ? 164.094 180.918 197.843 1.00 14.84 ? 36  PHE C CD2 1 
ATOM   6399 C CE1 . PHE C 3 37  ? 162.317 182.488 199.221 1.00 14.84 ? 36  PHE C CE1 1 
ATOM   6400 C CE2 . PHE C 3 37  ? 164.058 182.279 197.620 1.00 14.84 ? 36  PHE C CE2 1 
ATOM   6401 C CZ  . PHE C 3 37  ? 163.168 183.061 198.309 1.00 14.84 ? 36  PHE C CZ  1 
ATOM   6402 N N   . ASP C 3 38  ? 166.353 179.825 200.002 1.00 14.62 ? 37  ASP C N   1 
ATOM   6403 C CA  . ASP C 3 38  ? 167.673 180.260 199.570 1.00 14.62 ? 37  ASP C CA  1 
ATOM   6404 C C   . ASP C 3 38  ? 168.292 181.108 200.667 1.00 14.62 ? 37  ASP C C   1 
ATOM   6405 O O   . ASP C 3 38  ? 167.584 181.731 201.459 1.00 14.62 ? 37  ASP C O   1 
ATOM   6406 C CB  . ASP C 3 38  ? 167.604 181.050 198.261 1.00 14.62 ? 37  ASP C CB  1 
ATOM   6407 C CG  . ASP C 3 38  ? 168.974 181.406 197.717 1.00 14.62 ? 37  ASP C CG  1 
ATOM   6408 O OD1 . ASP C 3 38  ? 169.982 180.944 198.288 1.00 14.62 ? 37  ASP C OD1 1 
ATOM   6409 O OD2 . ASP C 3 38  ? 169.043 182.152 196.719 1.00 14.62 ? 37  ASP C OD2 1 
ATOM   6410 N N   . SER C 3 39  ? 169.621 181.125 200.701 1.00 13.05 ? 38  SER C N   1 
ATOM   6411 C CA  . SER C 3 39  ? 170.347 181.933 201.667 1.00 13.05 ? 38  SER C CA  1 
ATOM   6412 C C   . SER C 3 39  ? 171.732 182.242 201.132 1.00 13.05 ? 38  SER C C   1 
ATOM   6413 O O   . SER C 3 39  ? 172.296 181.475 200.351 1.00 13.05 ? 38  SER C O   1 
ATOM   6414 C CB  . SER C 3 39  ? 170.473 181.232 203.017 1.00 13.05 ? 38  SER C CB  1 
ATOM   6415 O OG  . SER C 3 39  ? 171.333 181.963 203.872 1.00 13.05 ? 38  SER C OG  1 
ATOM   6416 N N   . SER C 3 40  ? 172.280 183.371 201.570 1.00 14.37 ? 39  SER C N   1 
ATOM   6417 C CA  . SER C 3 40  ? 173.631 183.766 201.211 1.00 14.37 ? 39  SER C CA  1 
ATOM   6418 C C   . SER C 3 40  ? 174.631 183.455 202.303 1.00 14.37 ? 39  SER C C   1 
ATOM   6419 O O   . SER C 3 40  ? 175.743 183.988 202.278 1.00 14.37 ? 39  SER C O   1 
ATOM   6420 C CB  . SER C 3 40  ? 173.696 185.249 200.881 1.00 14.37 ? 39  SER C CB  1 
ATOM   6421 O OG  . SER C 3 40  ? 175.031 185.702 200.989 1.00 14.37 ? 39  SER C OG  1 
ATOM   6422 N N   . ARG C 3 41  ? 174.249 182.642 203.283 1.00 15.76 ? 40  ARG C N   1 
ATOM   6423 C CA  . ARG C 3 41  ? 175.195 182.081 204.231 1.00 15.76 ? 40  ARG C CA  1 
ATOM   6424 C C   . ARG C 3 41  ? 175.424 180.593 204.017 1.00 15.76 ? 40  ARG C C   1 
ATOM   6425 O O   . ARG C 3 41  ? 176.400 180.052 204.546 1.00 15.76 ? 40  ARG C O   1 
ATOM   6426 C CB  . ARG C 3 41  ? 174.729 182.347 205.667 1.00 15.76 ? 40  ARG C CB  1 
ATOM   6427 C CG  . ARG C 3 41  ? 174.632 183.826 205.984 1.00 15.76 ? 40  ARG C CG  1 
ATOM   6428 C CD  . ARG C 3 41  ? 174.266 184.073 207.426 1.00 15.76 ? 40  ARG C CD  1 
ATOM   6429 N NE  . ARG C 3 41  ? 174.012 185.484 207.690 1.00 15.76 ? 40  ARG C NE  1 
ATOM   6430 C CZ  . ARG C 3 41  ? 172.812 186.047 207.618 1.00 15.76 ? 40  ARG C CZ  1 
ATOM   6431 N NH1 . ARG C 3 41  ? 171.757 185.317 207.288 1.00 15.76 ? 40  ARG C NH1 1 
ATOM   6432 N NH2 . ARG C 3 41  ? 172.666 187.339 207.877 1.00 15.76 ? 40  ARG C NH2 1 
ATOM   6433 N N   . ASP C 3 42  ? 174.556 179.921 203.253 1.00 17.46 ? 41  ASP C N   1 
ATOM   6434 C CA  . ASP C 3 42  ? 174.886 178.604 202.723 1.00 17.46 ? 41  ASP C CA  1 
ATOM   6435 C C   . ASP C 3 42  ? 176.094 178.667 201.804 1.00 17.46 ? 41  ASP C C   1 
ATOM   6436 O O   . ASP C 3 42  ? 176.773 177.654 201.610 1.00 17.46 ? 41  ASP C O   1 
ATOM   6437 C CB  . ASP C 3 42  ? 173.693 178.018 201.970 1.00 17.46 ? 41  ASP C CB  1 
ATOM   6438 C CG  . ASP C 3 42  ? 172.433 177.981 202.809 1.00 17.46 ? 41  ASP C CG  1 
ATOM   6439 O OD1 . ASP C 3 42  ? 171.394 177.511 202.301 1.00 17.46 ? 41  ASP C OD1 1 
ATOM   6440 O OD2 . ASP C 3 42  ? 172.481 178.426 203.974 1.00 17.46 ? 41  ASP C OD2 1 
ATOM   6441 N N   . ARG C 3 43  ? 176.354 179.826 201.218 1.00 12.12 ? 42  ARG C N   1 
ATOM   6442 C CA  . ARG C 3 43  ? 177.617 180.149 200.582 1.00 12.12 ? 42  ARG C CA  1 
ATOM   6443 C C   . ARG C 3 43  ? 178.337 181.168 201.450 1.00 12.12 ? 42  ARG C C   1 
ATOM   6444 O O   . ARG C 3 43  ? 177.717 181.904 202.219 1.00 12.12 ? 42  ARG C O   1 
ATOM   6445 C CB  . ARG C 3 43  ? 177.397 180.712 199.177 1.00 12.12 ? 42  ARG C CB  1 
ATOM   6446 C CG  . ARG C 3 43  ? 176.163 180.163 198.493 1.00 12.12 ? 42  ARG C CG  1 
ATOM   6447 C CD  . ARG C 3 43  ? 176.014 180.721 197.095 1.00 12.12 ? 42  ARG C CD  1 
ATOM   6448 N NE  . ARG C 3 43  ? 175.676 182.140 197.088 1.00 12.12 ? 42  ARG C NE  1 
ATOM   6449 C CZ  . ARG C 3 43  ? 174.454 182.613 196.869 1.00 12.12 ? 42  ARG C CZ  1 
ATOM   6450 N NH1 . ARG C 3 43  ? 173.453 181.780 196.637 1.00 12.12 ? 42  ARG C NH1 1 
ATOM   6451 N NH2 . ARG C 3 43  ? 174.235 183.919 196.879 1.00 12.12 ? 42  ARG C NH2 1 
ATOM   6452 N N   . ASN C 3 44  ? 179.656 181.200 201.342 1.00 23.00 ? 43  ASN C N   1 
ATOM   6453 C CA  . ASN C 3 44  ? 180.445 182.166 202.102 1.00 23.00 ? 43  ASN C CA  1 
ATOM   6454 C C   . ASN C 3 44  ? 180.726 183.404 201.255 1.00 23.00 ? 43  ASN C C   1 
ATOM   6455 O O   . ASN C 3 44  ? 181.871 183.774 201.001 1.00 23.00 ? 43  ASN C O   1 
ATOM   6456 C CB  . ASN C 3 44  ? 181.736 181.522 202.594 1.00 23.00 ? 43  ASN C CB  1 
ATOM   6457 C CG  . ASN C 3 44  ? 182.505 182.418 203.540 1.00 23.00 ? 43  ASN C CG  1 
ATOM   6458 O OD1 . ASN C 3 44  ? 181.941 183.330 204.142 1.00 23.00 ? 43  ASN C OD1 1 
ATOM   6459 N ND2 . ASN C 3 44  ? 183.801 182.163 203.675 1.00 23.00 ? 43  ASN C ND2 1 
ATOM   6460 N N   . LYS C 3 45  ? 179.653 184.056 200.815 1.00 23.40 ? 44  LYS C N   1 
ATOM   6461 C CA  . LYS C 3 45  ? 179.838 185.167 199.892 1.00 23.40 ? 44  LYS C CA  1 
ATOM   6462 C C   . LYS C 3 45  ? 178.688 186.167 199.953 1.00 23.40 ? 44  LYS C C   1 
ATOM   6463 O O   . LYS C 3 45  ? 177.518 185.781 199.851 1.00 23.40 ? 44  LYS C O   1 
ATOM   6464 C CB  . LYS C 3 45  ? 180.008 184.629 198.474 1.00 23.40 ? 44  LYS C CB  1 
ATOM   6465 C CG  . LYS C 3 45  ? 180.421 185.672 197.477 1.00 23.40 ? 44  LYS C CG  1 
ATOM   6466 C CD  . LYS C 3 45  ? 181.058 185.025 196.280 1.00 23.40 ? 44  LYS C CD  1 
ATOM   6467 C CE  . LYS C 3 45  ? 182.398 184.450 196.672 1.00 23.40 ? 44  LYS C CE  1 
ATOM   6468 N NZ  . LYS C 3 45  ? 183.317 185.515 197.150 1.00 23.40 ? 44  LYS C NZ  1 
ATOM   6469 N N   . PRO C 3 46  ? 178.981 187.454 200.119 1.00 17.05 ? 45  PRO C N   1 
ATOM   6470 C CA  . PRO C 3 46  ? 177.917 188.459 200.126 1.00 17.05 ? 45  PRO C CA  1 
ATOM   6471 C C   . PRO C 3 46  ? 177.305 188.627 198.746 1.00 17.05 ? 45  PRO C C   1 
ATOM   6472 O O   . PRO C 3 46  ? 177.926 188.343 197.721 1.00 17.05 ? 45  PRO C O   1 
ATOM   6473 C CB  . PRO C 3 46  ? 178.636 189.740 200.568 1.00 17.05 ? 45  PRO C CB  1 
ATOM   6474 C CG  . PRO C 3 46  ? 179.976 189.307 201.058 1.00 17.05 ? 45  PRO C CG  1 
ATOM   6475 C CD  . PRO C 3 46  ? 180.303 188.060 200.322 1.00 17.05 ? 45  PRO C CD  1 
ATOM   6476 N N   . PHE C 3 47  ? 176.065 189.102 198.730 1.00 16.96 ? 46  PHE C N   1 
ATOM   6477 C CA  . PHE C 3 47  ? 175.361 189.402 197.492 1.00 16.96 ? 46  PHE C CA  1 
ATOM   6478 C C   . PHE C 3 47  ? 175.478 190.891 197.200 1.00 16.96 ? 46  PHE C C   1 
ATOM   6479 O O   . PHE C 3 47  ? 175.142 191.718 198.051 1.00 16.96 ? 46  PHE C O   1 
ATOM   6480 C CB  . PHE C 3 47  ? 173.892 188.994 197.585 1.00 16.96 ? 46  PHE C CB  1 
ATOM   6481 C CG  . PHE C 3 47  ? 173.120 189.221 196.322 1.00 16.96 ? 46  PHE C CG  1 
ATOM   6482 C CD1 . PHE C 3 47  ? 173.087 188.259 195.336 1.00 16.96 ? 46  PHE C CD1 1 
ATOM   6483 C CD2 . PHE C 3 47  ? 172.421 190.393 196.123 1.00 16.96 ? 46  PHE C CD2 1 
ATOM   6484 C CE1 . PHE C 3 47  ? 172.374 188.464 194.176 1.00 16.96 ? 46  PHE C CE1 1 
ATOM   6485 C CE2 . PHE C 3 47  ? 171.708 190.601 194.964 1.00 16.96 ? 46  PHE C CE2 1 
ATOM   6486 C CZ  . PHE C 3 47  ? 171.685 189.636 193.992 1.00 16.96 ? 46  PHE C CZ  1 
ATOM   6487 N N   . LYS C 3 48  ? 175.945 191.227 196.000 1.00 23.28 ? 47  LYS C N   1 
ATOM   6488 C CA  . LYS C 3 48  ? 176.211 192.605 195.605 1.00 23.28 ? 47  LYS C CA  1 
ATOM   6489 C C   . LYS C 3 48  ? 175.238 193.015 194.510 1.00 23.28 ? 47  LYS C C   1 
ATOM   6490 O O   . LYS C 3 48  ? 175.178 192.368 193.461 1.00 23.28 ? 47  LYS C O   1 
ATOM   6491 C CB  . LYS C 3 48  ? 177.648 192.754 195.107 1.00 23.28 ? 47  LYS C CB  1 
ATOM   6492 C CG  . LYS C 3 48  ? 178.675 192.131 196.027 1.00 23.28 ? 47  LYS C CG  1 
ATOM   6493 C CD  . LYS C 3 48  ? 180.084 192.285 195.489 1.00 23.28 ? 47  LYS C CD  1 
ATOM   6494 C CE  . LYS C 3 48  ? 180.600 193.696 195.700 1.00 23.28 ? 47  LYS C CE  1 
ATOM   6495 N NZ  . LYS C 3 48  ? 182.035 193.821 195.330 1.00 23.28 ? 47  LYS C NZ  1 
ATOM   6496 N N   . PHE C 3 49  ? 174.487 194.090 194.742 1.00 25.00 ? 48  PHE C N   1 
ATOM   6497 C CA  . PHE C 3 49  ? 173.498 194.523 193.763 1.00 25.00 ? 48  PHE C CA  1 
ATOM   6498 C C   . PHE C 3 49  ? 173.479 196.042 193.680 1.00 25.00 ? 48  PHE C C   1 
ATOM   6499 O O   . PHE C 3 49  ? 173.758 196.740 194.655 1.00 25.00 ? 48  PHE C O   1 
ATOM   6500 C CB  . PHE C 3 49  ? 172.101 193.989 194.103 1.00 25.00 ? 48  PHE C CB  1 
ATOM   6501 C CG  . PHE C 3 49  ? 171.369 194.806 195.121 1.00 25.00 ? 48  PHE C CG  1 
ATOM   6502 C CD1 . PHE C 3 49  ? 171.726 194.758 196.452 1.00 25.00 ? 48  PHE C CD1 1 
ATOM   6503 C CD2 . PHE C 3 49  ? 170.306 195.604 194.748 1.00 25.00 ? 48  PHE C CD2 1 
ATOM   6504 C CE1 . PHE C 3 49  ? 171.052 195.506 197.385 1.00 25.00 ? 48  PHE C CE1 1 
ATOM   6505 C CE2 . PHE C 3 49  ? 169.627 196.351 195.678 1.00 25.00 ? 48  PHE C CE2 1 
ATOM   6506 C CZ  . PHE C 3 49  ? 169.999 196.304 196.997 1.00 25.00 ? 48  PHE C CZ  1 
ATOM   6507 N N   . MET C 3 50  ? 173.123 196.550 192.505 1.00 26.08 ? 49  MET C N   1 
ATOM   6508 C CA  . MET C 3 50  ? 173.116 197.981 192.238 1.00 26.08 ? 49  MET C CA  1 
ATOM   6509 C C   . MET C 3 50  ? 171.688 198.469 192.055 1.00 26.08 ? 49  MET C C   1 
ATOM   6510 O O   . MET C 3 50  ? 170.881 197.814 191.389 1.00 26.08 ? 49  MET C O   1 
ATOM   6511 C CB  . MET C 3 50  ? 173.938 198.316 190.994 1.00 26.08 ? 49  MET C CB  1 
ATOM   6512 N N   . LEU C 3 51  ? 171.383 199.622 192.646 1.00 30.41 ? 50  LEU C N   1 
ATOM   6513 C CA  . LEU C 3 51  ? 170.061 200.218 192.542 1.00 30.41 ? 50  LEU C CA  1 
ATOM   6514 C C   . LEU C 3 51  ? 169.903 200.910 191.192 1.00 30.41 ? 50  LEU C C   1 
ATOM   6515 O O   . LEU C 3 51  ? 170.827 200.965 190.377 1.00 30.41 ? 50  LEU C O   1 
ATOM   6516 C CB  . LEU C 3 51  ? 169.828 201.200 193.686 1.00 30.41 ? 50  LEU C CB  1 
ATOM   6517 C CG  . LEU C 3 51  ? 169.726 200.600 195.085 1.00 30.41 ? 50  LEU C CG  1 
ATOM   6518 C CD1 . LEU C 3 51  ? 169.606 201.701 196.117 1.00 30.41 ? 50  LEU C CD1 1 
ATOM   6519 C CD2 . LEU C 3 51  ? 168.544 199.656 195.172 1.00 30.41 ? 50  LEU C CD2 1 
ATOM   6520 N N   . GLY C 3 52  ? 168.713 201.450 190.947 1.00 31.80 ? 51  GLY C N   1 
ATOM   6521 C CA  . GLY C 3 52  ? 168.443 202.109 189.685 1.00 31.80 ? 51  GLY C CA  1 
ATOM   6522 C C   . GLY C 3 52  ? 168.243 201.118 188.559 1.00 31.80 ? 51  GLY C C   1 
ATOM   6523 O O   . GLY C 3 52  ? 167.150 201.021 187.995 1.00 31.80 ? 51  GLY C O   1 
ATOM   6524 N N   . LYS C 3 53  ? 169.300 200.387 188.215 1.00 34.15 ? 52  LYS C N   1 
ATOM   6525 C CA  . LYS C 3 53  ? 169.165 199.277 187.284 1.00 34.15 ? 52  LYS C CA  1 
ATOM   6526 C C   . LYS C 3 53  ? 168.181 198.259 187.845 1.00 34.15 ? 52  LYS C C   1 
ATOM   6527 O O   . LYS C 3 53  ? 168.222 197.919 189.030 1.00 34.15 ? 52  LYS C O   1 
ATOM   6528 C CB  . LYS C 3 53  ? 170.526 198.627 187.033 1.00 34.15 ? 52  LYS C CB  1 
ATOM   6529 C CG  . LYS C 3 53  ? 170.497 197.463 186.061 1.00 34.15 ? 52  LYS C CG  1 
ATOM   6530 C CD  . LYS C 3 53  ? 170.233 197.922 184.643 1.00 34.15 ? 52  LYS C CD  1 
ATOM   6531 C CE  . LYS C 3 53  ? 170.131 196.736 183.695 1.00 34.15 ? 52  LYS C CE  1 
ATOM   6532 N NZ  . LYS C 3 53  ? 171.409 195.988 183.579 1.00 34.15 ? 52  LYS C NZ  1 
ATOM   6533 N N   . GLN C 3 54  ? 167.279 197.784 186.989 1.00 36.86 ? 53  GLN C N   1 
ATOM   6534 C CA  . GLN C 3 54  ? 166.164 196.945 187.424 1.00 36.86 ? 53  GLN C CA  1 
ATOM   6535 C C   . GLN C 3 54  ? 166.477 195.481 187.125 1.00 36.86 ? 53  GLN C C   1 
ATOM   6536 O O   . GLN C 3 54  ? 166.074 194.922 186.106 1.00 36.86 ? 53  GLN C O   1 
ATOM   6537 C CB  . GLN C 3 54  ? 164.869 197.395 186.756 1.00 36.86 ? 53  GLN C CB  1 
ATOM   6538 C CG  . GLN C 3 54  ? 164.369 198.760 187.211 1.00 36.86 ? 53  GLN C CG  1 
ATOM   6539 C CD  . GLN C 3 54  ? 163.746 198.733 188.596 1.00 36.86 ? 53  GLN C CD  1 
ATOM   6540 O OE1 . GLN C 3 54  ? 163.778 197.716 189.288 1.00 36.86 ? 53  GLN C OE1 1 
ATOM   6541 N NE2 . GLN C 3 54  ? 163.178 199.860 189.008 1.00 36.86 ? 53  GLN C NE2 1 
ATOM   6542 N N   . GLU C 3 55  ? 167.211 194.855 188.040 1.00 27.97 ? 54  GLU C N   1 
ATOM   6543 C CA  . GLU C 3 55  ? 167.399 193.410 188.022 1.00 27.97 ? 54  GLU C CA  1 
ATOM   6544 C C   . GLU C 3 55  ? 166.812 192.720 189.243 1.00 27.97 ? 54  GLU C C   1 
ATOM   6545 O O   . GLU C 3 55  ? 166.230 191.643 189.111 1.00 27.97 ? 54  GLU C O   1 
ATOM   6546 C CB  . GLU C 3 55  ? 168.890 193.059 187.885 1.00 27.97 ? 54  GLU C CB  1 
ATOM   6547 C CG  . GLU C 3 55  ? 169.752 193.313 189.111 1.00 27.97 ? 54  GLU C CG  1 
ATOM   6548 C CD  . GLU C 3 55  ? 170.418 194.671 189.090 1.00 27.97 ? 54  GLU C CD  1 
ATOM   6549 O OE1 . GLU C 3 55  ? 169.790 195.631 188.606 1.00 27.97 ? 54  GLU C OE1 1 
ATOM   6550 O OE2 . GLU C 3 55  ? 171.571 194.780 189.554 1.00 27.97 ? 54  GLU C OE2 1 
ATOM   6551 N N   . VAL C 3 56  ? 166.925 193.319 190.432 1.00 19.43 ? 55  VAL C N   1 
ATOM   6552 C CA  . VAL C 3 56  ? 166.272 192.749 191.601 1.00 19.43 ? 55  VAL C CA  1 
ATOM   6553 C C   . VAL C 3 56  ? 164.778 193.043 191.546 1.00 19.43 ? 55  VAL C C   1 
ATOM   6554 O O   . VAL C 3 56  ? 164.320 193.967 190.866 1.00 19.43 ? 55  VAL C O   1 
ATOM   6555 C CB  . VAL C 3 56  ? 166.891 193.295 192.895 1.00 19.43 ? 55  VAL C CB  1 
ATOM   6556 C CG1 . VAL C 3 56  ? 168.377 193.052 192.905 1.00 19.43 ? 55  VAL C CG1 1 
ATOM   6557 C CG2 . VAL C 3 56  ? 166.600 194.767 193.023 1.00 19.43 ? 55  VAL C CG2 1 
ATOM   6558 N N   . ILE C 3 57  ? 164.005 192.230 192.270 1.00 16.08 ? 56  ILE C N   1 
ATOM   6559 C CA  . ILE C 3 57  ? 162.576 192.482 192.381 1.00 16.08 ? 56  ILE C CA  1 
ATOM   6560 C C   . ILE C 3 57  ? 162.350 193.855 193.009 1.00 16.08 ? 56  ILE C C   1 
ATOM   6561 O O   . ILE C 3 57  ? 163.119 194.306 193.866 1.00 16.08 ? 56  ILE C O   1 
ATOM   6562 C CB  . ILE C 3 57  ? 161.897 191.367 193.194 1.00 16.08 ? 56  ILE C CB  1 
ATOM   6563 C CG1 . ILE C 3 57  ? 162.466 191.312 194.609 1.00 16.08 ? 56  ILE C CG1 1 
ATOM   6564 C CG2 . ILE C 3 57  ? 162.098 190.035 192.524 1.00 16.08 ? 56  ILE C CG2 1 
ATOM   6565 C CD1 . ILE C 3 57  ? 161.712 190.400 195.529 1.00 16.08 ? 56  ILE C CD1 1 
ATOM   6566 N N   . ARG C 3 58  ? 161.293 194.539 192.563 1.00 14.86 ? 57  ARG C N   1 
ATOM   6567 C CA  . ARG C 3 58  ? 161.062 195.910 193.007 1.00 14.86 ? 57  ARG C CA  1 
ATOM   6568 C C   . ARG C 3 58  ? 160.904 196.009 194.517 1.00 14.86 ? 57  ARG C C   1 
ATOM   6569 O O   . ARG C 3 58  ? 161.133 197.083 195.086 1.00 14.86 ? 57  ARG C O   1 
ATOM   6570 C CB  . ARG C 3 58  ? 159.828 196.488 192.315 1.00 14.86 ? 57  ARG C CB  1 
ATOM   6571 N N   . GLY C 3 59  ? 160.524 194.913 195.175 1.00 15.98 ? 58  GLY C N   1 
ATOM   6572 C CA  . GLY C 3 59  ? 160.453 194.920 196.625 1.00 15.98 ? 58  GLY C CA  1 
ATOM   6573 C C   . GLY C 3 59  ? 161.793 195.209 197.272 1.00 15.98 ? 58  GLY C C   1 
ATOM   6574 O O   . GLY C 3 59  ? 161.872 195.963 198.240 1.00 15.98 ? 58  GLY C O   1 
ATOM   6575 N N   . TRP C 3 60  ? 162.865 194.608 196.753 1.00 15.03 ? 59  TRP C N   1 
ATOM   6576 C CA  . TRP C 3 60  ? 164.201 194.980 197.204 1.00 15.03 ? 59  TRP C CA  1 
ATOM   6577 C C   . TRP C 3 60  ? 164.483 196.444 196.917 1.00 15.03 ? 59  TRP C C   1 
ATOM   6578 O O   . TRP C 3 60  ? 165.022 197.157 197.770 1.00 15.03 ? 59  TRP C O   1 
ATOM   6579 C CB  . TRP C 3 60  ? 165.247 194.105 196.523 1.00 15.03 ? 59  TRP C CB  1 
ATOM   6580 C CG  . TRP C 3 60  ? 165.530 192.820 197.202 1.00 15.03 ? 59  TRP C CG  1 
ATOM   6581 C CD1 . TRP C 3 60  ? 164.701 191.753 197.303 1.00 15.03 ? 59  TRP C CD1 1 
ATOM   6582 C CD2 . TRP C 3 60  ? 166.767 192.426 197.802 1.00 15.03 ? 59  TRP C CD2 1 
ATOM   6583 N NE1 . TRP C 3 60  ? 165.325 190.732 197.973 1.00 15.03 ? 59  TRP C NE1 1 
ATOM   6584 C CE2 . TRP C 3 60  ? 166.600 191.121 198.282 1.00 15.03 ? 59  TRP C CE2 1 
ATOM   6585 C CE3 . TRP C 3 60  ? 167.995 193.058 197.993 1.00 15.03 ? 59  TRP C CE3 1 
ATOM   6586 C CZ2 . TRP C 3 60  ? 167.611 190.437 198.942 1.00 15.03 ? 59  TRP C CZ2 1 
ATOM   6587 C CZ3 . TRP C 3 60  ? 168.996 192.377 198.649 1.00 15.03 ? 59  TRP C CZ3 1 
ATOM   6588 C CH2 . TRP C 3 60  ? 168.800 191.083 199.114 1.00 15.03 ? 59  TRP C CH2 1 
ATOM   6589 N N   . GLU C 3 61  ? 164.115 196.913 195.722 1.00 18.38 ? 60  GLU C N   1 
ATOM   6590 C CA  . GLU C 3 61  ? 164.474 198.266 195.309 1.00 18.38 ? 60  GLU C CA  1 
ATOM   6591 C C   . GLU C 3 61  ? 163.863 199.307 196.235 1.00 18.38 ? 60  GLU C C   1 
ATOM   6592 O O   . GLU C 3 61  ? 164.519 200.294 196.587 1.00 18.38 ? 60  GLU C O   1 
ATOM   6593 C CB  . GLU C 3 61  ? 164.040 198.510 193.864 1.00 18.38 ? 60  GLU C CB  1 
ATOM   6594 N N   . GLU C 3 62  ? 162.612 199.106 196.645 1.00 18.93 ? 61  GLU C N   1 
ATOM   6595 C CA  . GLU C 3 62  ? 161.950 200.043 197.543 1.00 18.93 ? 61  GLU C CA  1 
ATOM   6596 C C   . GLU C 3 62  ? 161.914 199.566 198.991 1.00 18.93 ? 61  GLU C C   1 
ATOM   6597 O O   . GLU C 3 62  ? 161.248 200.191 199.820 1.00 18.93 ? 61  GLU C O   1 
ATOM   6598 C CB  . GLU C 3 62  ? 160.530 200.334 197.047 1.00 18.93 ? 61  GLU C CB  1 
ATOM   6599 C CG  . GLU C 3 62  ? 159.968 201.659 197.538 1.00 18.93 ? 61  GLU C CG  1 
ATOM   6600 C CD  . GLU C 3 62  ? 160.840 202.848 197.172 1.00 18.93 ? 61  GLU C CD  1 
ATOM   6601 O OE1 . GLU C 3 62  ? 161.500 202.809 196.113 1.00 18.93 ? 61  GLU C OE1 1 
ATOM   6602 O OE2 . GLU C 3 62  ? 160.872 203.824 197.951 1.00 18.93 ? 61  GLU C OE2 1 
ATOM   6603 N N   . GLY C 3 63  ? 162.621 198.491 199.321 1.00 19.96 ? 62  GLY C N   1 
ATOM   6604 C CA  . GLY C 3 63  ? 162.638 198.000 200.683 1.00 19.96 ? 62  GLY C CA  1 
ATOM   6605 C C   . GLY C 3 63  ? 164.020 198.025 201.293 1.00 19.96 ? 62  GLY C C   1 
ATOM   6606 O O   . GLY C 3 63  ? 164.162 198.127 202.514 1.00 19.96 ? 62  GLY C O   1 
ATOM   6607 N N   . VAL C 3 64  ? 165.049 197.917 200.448 1.00 25.05 ? 63  VAL C N   1 
ATOM   6608 C CA  . VAL C 3 64  ? 166.428 198.054 200.906 1.00 25.05 ? 63  VAL C CA  1 
ATOM   6609 C C   . VAL C 3 64  ? 166.856 199.514 200.957 1.00 25.05 ? 63  VAL C C   1 
ATOM   6610 O O   . VAL C 3 64  ? 167.741 199.868 201.745 1.00 25.05 ? 63  VAL C O   1 
ATOM   6611 C CB  . VAL C 3 64  ? 167.372 197.237 200.006 1.00 25.05 ? 63  VAL C CB  1 
ATOM   6612 C CG1 . VAL C 3 64  ? 168.801 197.304 200.499 1.00 25.05 ? 63  VAL C CG1 1 
ATOM   6613 C CG2 . VAL C 3 64  ? 166.918 195.798 199.955 1.00 25.05 ? 63  VAL C CG2 1 
ATOM   6614 N N   . ALA C 3 65  ? 166.227 200.378 200.158 1.00 27.06 ? 64  ALA C N   1 
ATOM   6615 C CA  . ALA C 3 65  ? 166.567 201.794 200.186 1.00 27.06 ? 64  ALA C CA  1 
ATOM   6616 C C   . ALA C 3 65  ? 166.320 202.411 201.557 1.00 27.06 ? 64  ALA C C   1 
ATOM   6617 O O   . ALA C 3 65  ? 167.051 203.320 201.968 1.00 27.06 ? 64  ALA C O   1 
ATOM   6618 C CB  . ALA C 3 65  ? 165.772 202.541 199.117 1.00 27.06 ? 64  ALA C CB  1 
ATOM   6619 N N   . GLN C 3 66  ? 165.307 201.932 202.282 1.00 29.91 ? 65  GLN C N   1 
ATOM   6620 C CA  . GLN C 3 66  ? 164.969 202.491 203.587 1.00 29.91 ? 65  GLN C CA  1 
ATOM   6621 C C   . GLN C 3 66  ? 165.981 202.147 204.671 1.00 29.91 ? 65  GLN C C   1 
ATOM   6622 O O   . GLN C 3 66  ? 165.886 202.699 205.771 1.00 29.91 ? 65  GLN C O   1 
ATOM   6623 C CB  . GLN C 3 66  ? 163.588 202.008 204.030 1.00 29.91 ? 65  GLN C CB  1 
ATOM   6624 C CG  . GLN C 3 66  ? 162.509 202.123 202.975 1.00 29.91 ? 65  GLN C CG  1 
ATOM   6625 C CD  . GLN C 3 66  ? 161.201 201.505 203.423 1.00 29.91 ? 65  GLN C CD  1 
ATOM   6626 O OE1 . GLN C 3 66  ? 161.083 201.029 204.550 1.00 29.91 ? 65  GLN C OE1 1 
ATOM   6627 N NE2 . GLN C 3 66  ? 160.208 201.519 202.545 1.00 29.91 ? 65  GLN C NE2 1 
ATOM   6628 N N   . MET C 3 67  ? 166.929 201.256 204.404 1.00 30.28 ? 66  MET C N   1 
ATOM   6629 C CA  . MET C 3 67  ? 167.838 200.780 205.432 1.00 30.28 ? 66  MET C CA  1 
ATOM   6630 C C   . MET C 3 67  ? 169.033 201.721 205.579 1.00 30.28 ? 66  MET C C   1 
ATOM   6631 O O   . MET C 3 67  ? 169.056 202.831 205.041 1.00 30.28 ? 66  MET C O   1 
ATOM   6632 C CB  . MET C 3 67  ? 168.299 199.364 205.115 1.00 30.28 ? 66  MET C CB  1 
ATOM   6633 C CG  . MET C 3 67  ? 167.443 198.287 205.709 1.00 30.28 ? 66  MET C CG  1 
ATOM   6634 S SD  . MET C 3 67  ? 168.300 196.721 205.636 1.00 30.28 ? 66  MET C SD  1 
ATOM   6635 C CE  . MET C 3 67  ? 168.315 196.497 203.872 1.00 30.28 ? 66  MET C CE  1 
ATOM   6636 N N   . SER C 3 68  ? 170.041 201.272 206.322 1.00 39.28 ? 67  SER C N   1 
ATOM   6637 C CA  . SER C 3 68  ? 171.273 202.014 206.545 1.00 39.28 ? 67  SER C CA  1 
ATOM   6638 C C   . SER C 3 68  ? 172.406 201.006 206.699 1.00 39.28 ? 67  SER C C   1 
ATOM   6639 O O   . SER C 3 68  ? 172.262 199.826 206.370 1.00 39.28 ? 67  SER C O   1 
ATOM   6640 C CB  . SER C 3 68  ? 171.146 202.927 207.768 1.00 39.28 ? 67  SER C CB  1 
ATOM   6641 O OG  . SER C 3 68  ? 172.392 203.525 208.075 1.00 39.28 ? 67  SER C OG  1 
ATOM   6642 N N   . VAL C 3 69  ? 173.545 201.465 207.213 1.00 39.39 ? 68  VAL C N   1 
ATOM   6643 C CA  . VAL C 3 69  ? 174.681 200.572 207.400 1.00 39.39 ? 68  VAL C CA  1 
ATOM   6644 C C   . VAL C 3 69  ? 174.448 199.708 208.631 1.00 39.39 ? 68  VAL C C   1 
ATOM   6645 O O   . VAL C 3 69  ? 174.174 200.217 209.725 1.00 39.39 ? 68  VAL C O   1 
ATOM   6646 C CB  . VAL C 3 69  ? 175.987 201.370 207.522 1.00 39.39 ? 68  VAL C CB  1 
ATOM   6647 C CG1 . VAL C 3 69  ? 177.075 200.517 208.157 1.00 39.39 ? 68  VAL C CG1 1 
ATOM   6648 C CG2 . VAL C 3 69  ? 176.433 201.865 206.162 1.00 39.39 ? 68  VAL C CG2 1 
ATOM   6649 N N   . GLY C 3 70  ? 174.541 198.393 208.453 1.00 32.63 ? 69  GLY C N   1 
ATOM   6650 C CA  . GLY C 3 70  ? 174.504 197.458 209.556 1.00 32.63 ? 69  GLY C CA  1 
ATOM   6651 C C   . GLY C 3 70  ? 173.131 197.148 210.100 1.00 32.63 ? 69  GLY C C   1 
ATOM   6652 O O   . GLY C 3 70  ? 173.023 196.341 211.031 1.00 32.63 ? 69  GLY C O   1 
ATOM   6653 N N   . GLN C 3 71  ? 172.079 197.743 209.550 1.00 32.73 ? 70  GLN C N   1 
ATOM   6654 C CA  . GLN C 3 71  ? 170.741 197.613 210.120 1.00 32.73 ? 70  GLN C CA  1 
ATOM   6655 C C   . GLN C 3 71  ? 170.090 196.360 209.555 1.00 32.73 ? 70  GLN C C   1 
ATOM   6656 O O   . GLN C 3 71  ? 169.480 196.378 208.487 1.00 32.73 ? 70  GLN C O   1 
ATOM   6657 C CB  . GLN C 3 71  ? 169.911 198.856 209.832 1.00 32.73 ? 70  GLN C CB  1 
ATOM   6658 C CG  . GLN C 3 71  ? 168.479 198.773 210.319 1.00 32.73 ? 70  GLN C CG  1 
ATOM   6659 C CD  . GLN C 3 71  ? 167.621 199.885 209.765 1.00 32.73 ? 70  GLN C CD  1 
ATOM   6660 O OE1 . GLN C 3 71  ? 168.115 200.793 209.100 1.00 32.73 ? 70  GLN C OE1 1 
ATOM   6661 N NE2 . GLN C 3 71  ? 166.324 199.820 210.035 1.00 32.73 ? 70  GLN C NE2 1 
ATOM   6662 N N   . ARG C 3 72  ? 170.227 195.255 210.282 1.00 29.25 ? 71  ARG C N   1 
ATOM   6663 C CA  . ARG C 3 72  ? 169.508 194.042 209.924 1.00 29.25 ? 71  ARG C CA  1 
ATOM   6664 C C   . ARG C 3 72  ? 168.009 194.306 209.957 1.00 29.25 ? 71  ARG C C   1 
ATOM   6665 O O   . ARG C 3 72  ? 167.510 195.031 210.819 1.00 29.25 ? 71  ARG C O   1 
ATOM   6666 C CB  . ARG C 3 72  ? 169.875 192.907 210.879 1.00 29.25 ? 71  ARG C CB  1 
ATOM   6667 C CG  . ARG C 3 72  ? 169.370 191.549 210.438 1.00 29.25 ? 71  ARG C CG  1 
ATOM   6668 C CD  . ARG C 3 72  ? 169.847 190.438 211.361 1.00 29.25 ? 71  ARG C CD  1 
ATOM   6669 N NE  . ARG C 3 72  ? 169.564 189.120 210.799 1.00 29.25 ? 71  ARG C NE  1 
ATOM   6670 C CZ  . ARG C 3 72  ? 168.376 188.526 210.843 1.00 29.25 ? 71  ARG C CZ  1 
ATOM   6671 N NH1 . ARG C 3 72  ? 167.353 189.124 211.437 1.00 29.25 ? 71  ARG C NH1 1 
ATOM   6672 N NH2 . ARG C 3 72  ? 168.213 187.329 210.298 1.00 29.25 ? 71  ARG C NH2 1 
ATOM   6673 N N   . ALA C 3 73  ? 167.289 193.724 209.005 1.00 19.15 ? 72  ALA C N   1 
ATOM   6674 C CA  . ALA C 3 73  ? 165.878 194.028 208.830 1.00 19.15 ? 72  ALA C CA  1 
ATOM   6675 C C   . ALA C 3 73  ? 165.133 192.732 208.557 1.00 19.15 ? 72  ALA C C   1 
ATOM   6676 O O   . ALA C 3 73  ? 165.665 191.635 208.742 1.00 19.15 ? 72  ALA C O   1 
ATOM   6677 C CB  . ALA C 3 73  ? 165.674 195.047 207.704 1.00 19.15 ? 72  ALA C CB  1 
ATOM   6678 N N   . LYS C 3 74  ? 163.886 192.863 208.124 1.00 15.85 ? 73  LYS C N   1 
ATOM   6679 C CA  . LYS C 3 74  ? 163.067 191.712 207.788 1.00 15.85 ? 73  LYS C CA  1 
ATOM   6680 C C   . LYS C 3 74  ? 161.965 192.166 206.845 1.00 15.85 ? 73  LYS C C   1 
ATOM   6681 O O   . LYS C 3 74  ? 161.001 192.808 207.265 1.00 15.85 ? 73  LYS C O   1 
ATOM   6682 C CB  . LYS C 3 74  ? 162.472 191.070 209.042 1.00 15.85 ? 73  LYS C CB  1 
ATOM   6683 C CG  . LYS C 3 74  ? 161.906 189.694 208.819 1.00 15.85 ? 73  LYS C CG  1 
ATOM   6684 C CD  . LYS C 3 74  ? 161.612 189.008 210.131 1.00 15.85 ? 73  LYS C CD  1 
ATOM   6685 C CE  . LYS C 3 74  ? 160.742 187.788 209.909 1.00 15.85 ? 73  LYS C CE  1 
ATOM   6686 N NZ  . LYS C 3 74  ? 159.341 188.175 209.576 1.00 15.85 ? 73  LYS C NZ  1 
ATOM   6687 N N   . LEU C 3 75  ? 162.101 191.802 205.577 1.00 12.85 ? 74  LEU C N   1 
ATOM   6688 C CA  . LEU C 3 75  ? 161.255 192.319 204.514 1.00 12.85 ? 74  LEU C CA  1 
ATOM   6689 C C   . LEU C 3 75  ? 160.082 191.379 204.308 1.00 12.85 ? 74  LEU C C   1 
ATOM   6690 O O   . LEU C 3 75  ? 160.261 190.159 204.320 1.00 12.85 ? 74  LEU C O   1 
ATOM   6691 C CB  . LEU C 3 75  ? 162.051 192.454 203.219 1.00 12.85 ? 74  LEU C CB  1 
ATOM   6692 C CG  . LEU C 3 75  ? 162.653 193.816 202.904 1.00 12.85 ? 74  LEU C CG  1 
ATOM   6693 C CD1 . LEU C 3 75  ? 163.662 194.211 203.951 1.00 12.85 ? 74  LEU C CD1 1 
ATOM   6694 C CD2 . LEU C 3 75  ? 163.306 193.751 201.555 1.00 12.85 ? 74  LEU C CD2 1 
ATOM   6695 N N   . THR C 3 76  ? 158.894 191.943 204.112 1.00 13.03 ? 75  THR C N   1 
ATOM   6696 C CA  . THR C 3 76  ? 157.691 191.182 203.773 1.00 13.03 ? 75  THR C CA  1 
ATOM   6697 C C   . THR C 3 76  ? 157.244 191.614 202.378 1.00 13.03 ? 75  THR C C   1 
ATOM   6698 O O   . THR C 3 76  ? 156.453 192.542 202.221 1.00 13.03 ? 75  THR C O   1 
ATOM   6699 C CB  . THR C 3 76  ? 156.592 191.401 204.798 1.00 13.03 ? 75  THR C CB  1 
ATOM   6700 O OG1 . THR C 3 76  ? 157.102 191.120 206.105 1.00 13.03 ? 75  THR C OG1 1 
ATOM   6701 C CG2 . THR C 3 76  ? 155.423 190.481 204.518 1.00 13.03 ? 75  THR C CG2 1 
ATOM   6702 N N   . ILE C 3 77  ? 157.753 190.923 201.365 1.00 12.74 ? 76  ILE C N   1 
ATOM   6703 C CA  . ILE C 3 77  ? 157.508 191.287 199.976 1.00 12.74 ? 76  ILE C CA  1 
ATOM   6704 C C   . ILE C 3 77  ? 156.173 190.704 199.529 1.00 12.74 ? 76  ILE C C   1 
ATOM   6705 O O   . ILE C 3 77  ? 155.969 189.487 199.573 1.00 12.74 ? 76  ILE C O   1 
ATOM   6706 C CB  . ILE C 3 77  ? 158.646 190.796 199.075 1.00 12.74 ? 76  ILE C CB  1 
ATOM   6707 C CG1 . ILE C 3 77  ? 159.989 191.338 199.562 1.00 12.74 ? 76  ILE C CG1 1 
ATOM   6708 C CG2 . ILE C 3 77  ? 158.387 191.197 197.642 1.00 12.74 ? 76  ILE C CG2 1 
ATOM   6709 C CD1 . ILE C 3 77  ? 160.126 192.818 199.452 1.00 12.74 ? 76  ILE C CD1 1 
ATOM   6710 N N   . SER C 3 78  ? 155.273 191.571 199.081 1.00 13.13 ? 77  SER C N   1 
ATOM   6711 C CA  . SER C 3 78  ? 153.968 191.188 198.574 1.00 13.13 ? 77  SER C CA  1 
ATOM   6712 C C   . SER C 3 78  ? 154.092 190.582 197.179 1.00 13.13 ? 77  SER C C   1 
ATOM   6713 O O   . SER C 3 78  ? 155.126 190.722 196.525 1.00 13.13 ? 77  SER C O   1 
ATOM   6714 C CB  . SER C 3 78  ? 153.055 192.406 198.541 1.00 13.13 ? 77  SER C CB  1 
ATOM   6715 O OG  . SER C 3 78  ? 152.956 192.995 199.823 1.00 13.13 ? 77  SER C OG  1 
ATOM   6716 N N   . PRO C 3 79  ? 153.059 189.876 196.707 1.00 17.90 ? 78  PRO C N   1 
ATOM   6717 C CA  . PRO C 3 79  ? 153.104 189.347 195.333 1.00 17.90 ? 78  PRO C CA  1 
ATOM   6718 C C   . PRO C 3 79  ? 153.156 190.419 194.264 1.00 17.90 ? 78  PRO C C   1 
ATOM   6719 O O   . PRO C 3 79  ? 153.539 190.115 193.129 1.00 17.90 ? 78  PRO C O   1 
ATOM   6720 C CB  . PRO C 3 79  ? 151.815 188.524 195.228 1.00 17.90 ? 78  PRO C CB  1 
ATOM   6721 C CG  . PRO C 3 79  ? 151.445 188.214 196.620 1.00 17.90 ? 78  PRO C CG  1 
ATOM   6722 C CD  . PRO C 3 79  ? 151.872 189.395 197.430 1.00 17.90 ? 78  PRO C CD  1 
ATOM   6723 N N   . ASP C 3 80  ? 152.753 191.654 194.574 1.00 19.20 ? 79  ASP C N   1 
ATOM   6724 C CA  . ASP C 3 80  ? 152.884 192.741 193.608 1.00 19.20 ? 79  ASP C CA  1 
ATOM   6725 C C   . ASP C 3 80  ? 154.347 193.051 193.317 1.00 19.20 ? 79  ASP C C   1 
ATOM   6726 O O   . ASP C 3 80  ? 154.720 193.305 192.166 1.00 19.20 ? 79  ASP C O   1 
ATOM   6727 C CB  . ASP C 3 80  ? 152.172 193.991 194.124 1.00 19.20 ? 79  ASP C CB  1 
ATOM   6728 C CG  . ASP C 3 80  ? 150.671 193.829 194.179 1.00 19.20 ? 79  ASP C CG  1 
ATOM   6729 O OD1 . ASP C 3 80  ? 150.087 193.365 193.180 1.00 19.20 ? 79  ASP C OD1 1 
ATOM   6730 O OD2 . ASP C 3 80  ? 150.074 194.174 195.219 1.00 19.20 ? 79  ASP C OD2 1 
ATOM   6731 N N   . TYR C 3 81  ? 155.188 193.046 194.347 1.00 16.17 ? 80  TYR C N   1 
ATOM   6732 C CA  . TYR C 3 81  ? 156.593 193.387 194.197 1.00 16.17 ? 80  TYR C CA  1 
ATOM   6733 C C   . TYR C 3 81  ? 157.507 192.175 194.195 1.00 16.17 ? 80  TYR C C   1 
ATOM   6734 O O   . TYR C 3 81  ? 158.721 192.335 194.038 1.00 16.17 ? 80  TYR C O   1 
ATOM   6735 C CB  . TYR C 3 81  ? 157.054 194.236 195.383 1.00 16.17 ? 80  TYR C CB  1 
ATOM   6736 C CG  . TYR C 3 81  ? 156.325 195.553 195.500 1.00 16.17 ? 80  TYR C CG  1 
ATOM   6737 C CD1 . TYR C 3 81  ? 155.565 196.046 194.448 1.00 16.17 ? 80  TYR C CD1 1 
ATOM   6738 C CD2 . TYR C 3 81  ? 156.390 196.301 196.662 1.00 16.17 ? 80  TYR C CD2 1 
ATOM   6739 C CE1 . TYR C 3 81  ? 154.897 197.247 194.551 1.00 16.17 ? 80  TYR C CE1 1 
ATOM   6740 C CE2 . TYR C 3 81  ? 155.726 197.502 196.771 1.00 16.17 ? 80  TYR C CE2 1 
ATOM   6741 C CZ  . TYR C 3 81  ? 154.982 197.970 195.715 1.00 16.17 ? 80  TYR C CZ  1 
ATOM   6742 O OH  . TYR C 3 81  ? 154.320 199.167 195.825 1.00 16.17 ? 80  TYR C OH  1 
ATOM   6743 N N   . ALA C 3 82  ? 156.959 190.978 194.359 1.00 19.66 ? 81  ALA C N   1 
ATOM   6744 C CA  . ALA C 3 82  ? 157.725 189.746 194.234 1.00 19.66 ? 81  ALA C CA  1 
ATOM   6745 C C   . ALA C 3 82  ? 157.553 189.321 192.779 1.00 19.66 ? 81  ALA C C   1 
ATOM   6746 O O   . ALA C 3 82  ? 157.185 190.117 191.912 1.00 19.66 ? 81  ALA C O   1 
ATOM   6747 C CB  . ALA C 3 82  ? 157.250 188.677 195.211 1.00 19.66 ? 81  ALA C CB  1 
ATOM   6748 N N   . TYR C 3 83  ? 157.846 188.055 192.486 1.00 18.73 ? 82  TYR C N   1 
ATOM   6749 C CA  . TYR C 3 83  ? 157.809 187.587 191.106 1.00 18.73 ? 82  TYR C CA  1 
ATOM   6750 C C   . TYR C 3 83  ? 156.414 187.657 190.497 1.00 18.73 ? 82  TYR C C   1 
ATOM   6751 O O   . TYR C 3 83  ? 156.283 187.573 189.272 1.00 18.73 ? 82  TYR C O   1 
ATOM   6752 C CB  . TYR C 3 83  ? 158.363 186.166 191.037 1.00 18.73 ? 82  TYR C CB  1 
ATOM   6753 C CG  . TYR C 3 83  ? 159.810 186.103 191.453 1.00 18.73 ? 82  TYR C CG  1 
ATOM   6754 C CD1 . TYR C 3 83  ? 160.162 186.002 192.787 1.00 18.73 ? 82  TYR C CD1 1 
ATOM   6755 C CD2 . TYR C 3 83  ? 160.822 186.173 190.516 1.00 18.73 ? 82  TYR C CD2 1 
ATOM   6756 C CE1 . TYR C 3 83  ? 161.477 185.960 193.174 1.00 18.73 ? 82  TYR C CE1 1 
ATOM   6757 C CE2 . TYR C 3 83  ? 162.140 186.130 190.894 1.00 18.73 ? 82  TYR C CE2 1 
ATOM   6758 C CZ  . TYR C 3 83  ? 162.460 186.024 192.225 1.00 18.73 ? 82  TYR C CZ  1 
ATOM   6759 O OH  . TYR C 3 83  ? 163.775 185.981 192.611 1.00 18.73 ? 82  TYR C OH  1 
ATOM   6760 N N   . GLY C 3 84  ? 155.374 187.812 191.310 1.00 29.72 ? 83  GLY C N   1 
ATOM   6761 C CA  . GLY C 3 84  ? 154.055 188.071 190.767 1.00 29.72 ? 83  GLY C CA  1 
ATOM   6762 C C   . GLY C 3 84  ? 153.374 186.823 190.231 1.00 29.72 ? 83  GLY C C   1 
ATOM   6763 O O   . GLY C 3 84  ? 153.637 185.701 190.665 1.00 29.72 ? 83  GLY C O   1 
ATOM   6764 N N   . ALA C 3 85  ? 152.478 187.037 189.264 1.00 32.97 ? 84  ALA C N   1 
ATOM   6765 C CA  . ALA C 3 85  ? 151.639 185.949 188.769 1.00 32.97 ? 84  ALA C CA  1 
ATOM   6766 C C   . ALA C 3 85  ? 152.467 184.854 188.110 1.00 32.97 ? 84  ALA C C   1 
ATOM   6767 O O   . ALA C 3 85  ? 152.189 183.664 188.292 1.00 32.97 ? 84  ALA C O   1 
ATOM   6768 C CB  . ALA C 3 85  ? 150.601 186.494 187.790 1.00 32.97 ? 84  ALA C CB  1 
ATOM   6769 N N   . THR C 3 86  ? 153.483 185.235 187.335 1.00 37.71 ? 85  THR C N   1 
ATOM   6770 C CA  . THR C 3 86  ? 154.267 184.243 186.609 1.00 37.71 ? 85  THR C CA  1 
ATOM   6771 C C   . THR C 3 86  ? 155.077 183.355 187.548 1.00 37.71 ? 85  THR C C   1 
ATOM   6772 O O   . THR C 3 86  ? 155.263 182.168 187.262 1.00 37.71 ? 85  THR C O   1 
ATOM   6773 C CB  . THR C 3 86  ? 155.188 184.931 185.599 1.00 37.71 ? 85  THR C CB  1 
ATOM   6774 O OG1 . THR C 3 86  ? 156.039 183.957 184.983 1.00 37.71 ? 85  THR C OG1 1 
ATOM   6775 C CG2 . THR C 3 86  ? 156.041 185.994 186.275 1.00 37.71 ? 85  THR C CG2 1 
ATOM   6776 N N   . GLY C 3 87  ? 155.560 183.899 188.660 1.00 29.13 ? 86  GLY C N   1 
ATOM   6777 C CA  . GLY C 3 87  ? 156.375 183.115 189.558 1.00 29.13 ? 86  GLY C CA  1 
ATOM   6778 C C   . GLY C 3 87  ? 157.736 182.822 188.951 1.00 29.13 ? 86  GLY C C   1 
ATOM   6779 O O   . GLY C 3 87  ? 158.172 183.441 187.983 1.00 29.13 ? 86  GLY C O   1 
ATOM   6780 N N   . HIS C 3 88  ? 158.410 181.847 189.550 1.00 23.27 ? 87  HIS C N   1 
ATOM   6781 C CA  . HIS C 3 88  ? 159.723 181.415 189.090 1.00 23.27 ? 87  HIS C CA  1 
ATOM   6782 C C   . HIS C 3 88  ? 159.735 179.897 188.993 1.00 23.27 ? 87  HIS C C   1 
ATOM   6783 O O   . HIS C 3 88  ? 159.479 179.219 190.002 1.00 23.27 ? 87  HIS C O   1 
ATOM   6784 C CB  . HIS C 3 88  ? 160.818 181.902 190.039 1.00 23.27 ? 87  HIS C CB  1 
ATOM   6785 C CG  . HIS C 3 88  ? 162.195 181.848 189.457 1.00 23.27 ? 87  HIS C CG  1 
ATOM   6786 N ND1 . HIS C 3 88  ? 162.817 180.664 189.125 1.00 23.27 ? 87  HIS C ND1 1 
ATOM   6787 C CD2 . HIS C 3 88  ? 163.074 182.832 189.158 1.00 23.27 ? 87  HIS C CD2 1 
ATOM   6788 C CE1 . HIS C 3 88  ? 164.019 180.922 188.642 1.00 23.27 ? 87  HIS C CE1 1 
ATOM   6789 N NE2 . HIS C 3 88  ? 164.199 182.230 188.651 1.00 23.27 ? 87  HIS C NE2 1 
ATOM   6790 N N   . PRO C 3 89  ? 160.033 179.319 187.791 1.00 23.02 ? 88  PRO C N   1 
ATOM   6791 C CA  . PRO C 3 89  ? 160.132 177.869 187.625 1.00 23.02 ? 88  PRO C CA  1 
ATOM   6792 C C   . PRO C 3 89  ? 161.190 177.285 188.563 1.00 23.02 ? 88  PRO C C   1 
ATOM   6793 O O   . PRO C 3 89  ? 162.172 177.942 188.842 1.00 23.02 ? 88  PRO C O   1 
ATOM   6794 C CB  . PRO C 3 89  ? 160.545 177.631 186.163 1.00 23.02 ? 88  PRO C CB  1 
ATOM   6795 C CG  . PRO C 3 89  ? 161.116 178.952 185.722 1.00 23.02 ? 88  PRO C CG  1 
ATOM   6796 C CD  . PRO C 3 89  ? 160.284 179.965 186.476 1.00 23.02 ? 88  PRO C CD  1 
ATOM   6797 N N   . GLY C 3 90  ? 160.979 176.049 188.992 1.00 19.96 ? 89  GLY C N   1 
ATOM   6798 C CA  . GLY C 3 90  ? 161.871 175.424 189.944 1.00 19.96 ? 89  GLY C CA  1 
ATOM   6799 C C   . GLY C 3 90  ? 161.666 175.632 191.430 1.00 19.96 ? 89  GLY C C   1 
ATOM   6800 O O   . GLY C 3 90  ? 161.489 174.656 192.163 1.00 19.96 ? 89  GLY C O   1 
ATOM   6801 N N   . ILE C 3 91  ? 161.683 176.879 191.896 1.00 19.72 ? 90  ILE C N   1 
ATOM   6802 C CA  . ILE C 3 91  ? 161.649 177.174 193.320 1.00 19.72 ? 90  ILE C CA  1 
ATOM   6803 C C   . ILE C 3 91  ? 160.287 177.691 193.767 1.00 19.72 ? 90  ILE C C   1 
ATOM   6804 O O   . ILE C 3 91  ? 159.600 177.034 194.552 1.00 19.72 ? 90  ILE C O   1 
ATOM   6805 C CB  . ILE C 3 91  ? 162.754 178.178 193.706 1.00 19.72 ? 90  ILE C CB  1 
ATOM   6806 C CG1 . ILE C 3 91  ? 164.134 177.615 193.413 1.00 19.72 ? 90  ILE C CG1 1 
ATOM   6807 C CG2 . ILE C 3 91  ? 162.667 178.504 195.172 1.00 19.72 ? 90  ILE C CG2 1 
ATOM   6808 C CD1 . ILE C 3 91  ? 165.238 178.557 193.807 1.00 19.72 ? 90  ILE C CD1 1 
ATOM   6809 N N   . ILE C 3 92  ? 159.879 178.856 193.279 1.00 22.83 ? 91  ILE C N   1 
ATOM   6810 C CA  . ILE C 3 92  ? 158.817 179.644 193.888 1.00 22.83 ? 91  ILE C CA  1 
ATOM   6811 C C   . ILE C 3 92  ? 157.507 179.394 193.148 1.00 22.83 ? 91  ILE C C   1 
ATOM   6812 O O   . ILE C 3 92  ? 157.447 179.555 191.927 1.00 22.83 ? 91  ILE C O   1 
ATOM   6813 C CB  . ILE C 3 92  ? 159.158 181.143 193.893 1.00 22.83 ? 91  ILE C CB  1 
ATOM   6814 C CG1 . ILE C 3 92  ? 160.487 181.371 194.602 1.00 22.83 ? 91  ILE C CG1 1 
ATOM   6815 C CG2 . ILE C 3 92  ? 158.071 181.927 194.577 1.00 22.83 ? 91  ILE C CG2 1 
ATOM   6816 C CD1 . ILE C 3 92  ? 160.880 182.813 194.683 1.00 22.83 ? 91  ILE C CD1 1 
ATOM   6817 N N   . PRO C 3 93  ? 156.440 179.003 193.837 1.00 27.29 ? 92  PRO C N   1 
ATOM   6818 C CA  . PRO C 3 93  ? 155.141 178.852 193.184 1.00 27.29 ? 92  PRO C CA  1 
ATOM   6819 C C   . PRO C 3 93  ? 154.536 180.206 192.862 1.00 27.29 ? 92  PRO C C   1 
ATOM   6820 O O   . PRO C 3 93  ? 154.942 181.226 193.437 1.00 27.29 ? 92  PRO C O   1 
ATOM   6821 C CB  . PRO C 3 93  ? 154.309 178.105 194.235 1.00 27.29 ? 92  PRO C CB  1 
ATOM   6822 C CG  . PRO C 3 93  ? 154.908 178.505 195.526 1.00 27.29 ? 92  PRO C CG  1 
ATOM   6823 C CD  . PRO C 3 93  ? 156.380 178.683 195.272 1.00 27.29 ? 92  PRO C CD  1 
ATOM   6824 N N   . PRO C 3 94  ? 153.571 180.261 191.947 1.00 29.21 ? 93  PRO C N   1 
ATOM   6825 C CA  . PRO C 3 94  ? 152.945 181.545 191.617 1.00 29.21 ? 93  PRO C CA  1 
ATOM   6826 C C   . PRO C 3 94  ? 152.164 182.111 192.791 1.00 29.21 ? 93  PRO C C   1 
ATOM   6827 O O   . PRO C 3 94  ? 151.688 181.378 193.662 1.00 29.21 ? 93  PRO C O   1 
ATOM   6828 C CB  . PRO C 3 94  ? 152.013 181.199 190.450 1.00 29.21 ? 93  PRO C CB  1 
ATOM   6829 C CG  . PRO C 3 94  ? 152.495 179.888 189.936 1.00 29.21 ? 93  PRO C CG  1 
ATOM   6830 C CD  . PRO C 3 94  ? 153.052 179.167 191.114 1.00 29.21 ? 93  PRO C CD  1 
ATOM   6831 N N   . HIS C 3 95  ? 152.043 183.440 192.804 1.00 33.61 ? 94  HIS C N   1 
ATOM   6832 C CA  . HIS C 3 95  ? 151.328 184.173 193.849 1.00 33.61 ? 94  HIS C CA  1 
ATOM   6833 C C   . HIS C 3 95  ? 151.918 183.874 195.227 1.00 33.61 ? 94  HIS C C   1 
ATOM   6834 O O   . HIS C 3 95  ? 151.272 183.295 196.102 1.00 33.61 ? 94  HIS C O   1 
ATOM   6835 C CB  . HIS C 3 95  ? 149.828 183.865 193.815 1.00 33.61 ? 94  HIS C CB  1 
ATOM   6836 C CG  . HIS C 3 95  ? 149.120 184.441 192.631 1.00 33.61 ? 94  HIS C CG  1 
ATOM   6837 N ND1 . HIS C 3 95  ? 149.668 184.449 191.367 1.00 33.61 ? 94  HIS C ND1 1 
ATOM   6838 C CD2 . HIS C 3 95  ? 147.907 185.031 192.520 1.00 33.61 ? 94  HIS C CD2 1 
ATOM   6839 C CE1 . HIS C 3 95  ? 148.822 185.017 190.527 1.00 33.61 ? 94  HIS C CE1 1 
ATOM   6840 N NE2 . HIS C 3 95  ? 147.746 185.380 191.201 1.00 33.61 ? 94  HIS C NE2 1 
ATOM   6841 N N   . ALA C 3 96  ? 153.171 184.283 195.404 1.00 23.61 ? 95  ALA C N   1 
ATOM   6842 C CA  . ALA C 3 96  ? 153.924 184.006 196.617 1.00 23.61 ? 95  ALA C CA  1 
ATOM   6843 C C   . ALA C 3 96  ? 154.203 185.302 197.359 1.00 23.61 ? 95  ALA C C   1 
ATOM   6844 O O   . ALA C 3 96  ? 154.536 186.315 196.739 1.00 23.61 ? 95  ALA C O   1 
ATOM   6845 C CB  . ALA C 3 96  ? 155.238 183.297 196.295 1.00 23.61 ? 95  ALA C CB  1 
ATOM   6846 N N   . THR C 3 97  ? 154.047 185.270 198.678 1.00 14.86 ? 96  THR C N   1 
ATOM   6847 C CA  . THR C 3 97  ? 154.494 186.351 199.541 1.00 14.86 ? 96  THR C CA  1 
ATOM   6848 C C   . THR C 3 97  ? 155.785 185.920 200.218 1.00 14.86 ? 96  THR C C   1 
ATOM   6849 O O   . THR C 3 97  ? 155.827 184.872 200.866 1.00 14.86 ? 96  THR C O   1 
ATOM   6850 C CB  . THR C 3 97  ? 153.433 186.689 200.586 1.00 14.86 ? 96  THR C CB  1 
ATOM   6851 O OG1 . THR C 3 97  ? 152.303 187.286 199.945 1.00 14.86 ? 96  THR C OG1 1 
ATOM   6852 C CG2 . THR C 3 97  ? 153.986 187.652 201.609 1.00 14.86 ? 96  THR C CG2 1 
ATOM   6853 N N   . LEU C 3 98  ? 156.833 186.721 200.071 1.00 11.71 ? 97  LEU C N   1 
ATOM   6854 C CA  . LEU C 3 98  ? 158.167 186.324 200.496 1.00 11.71 ? 97  LEU C CA  1 
ATOM   6855 C C   . LEU C 3 98  ? 158.587 187.086 201.744 1.00 11.71 ? 97  LEU C C   1 
ATOM   6856 O O   . LEU C 3 98  ? 158.079 188.165 202.040 1.00 11.71 ? 97  LEU C O   1 
ATOM   6857 C CB  . LEU C 3 98  ? 159.185 186.555 199.379 1.00 11.71 ? 97  LEU C CB  1 
ATOM   6858 C CG  . LEU C 3 98  ? 159.396 185.399 198.407 1.00 11.71 ? 97  LEU C CG  1 
ATOM   6859 C CD1 . LEU C 3 98  ? 158.160 185.183 197.569 1.00 11.71 ? 97  LEU C CD1 1 
ATOM   6860 C CD2 . LEU C 3 98  ? 160.584 185.688 197.521 1.00 11.71 ? 97  LEU C CD2 1 
ATOM   6861 N N   . VAL C 3 99  ? 159.524 186.502 202.484 1.00 10.51 ? 98  VAL C N   1 
ATOM   6862 C CA  . VAL C 3 99  ? 160.049 187.109 203.700 1.00 10.51 ? 98  VAL C CA  1 
ATOM   6863 C C   . VAL C 3 99  ? 161.564 186.999 203.644 1.00 10.51 ? 98  VAL C C   1 
ATOM   6864 O O   . VAL C 3 99  ? 162.106 185.893 203.566 1.00 10.51 ? 98  VAL C O   1 
ATOM   6865 C CB  . VAL C 3 99  ? 159.504 186.442 204.969 1.00 10.51 ? 98  VAL C CB  1 
ATOM   6866 C CG1 . VAL C 3 99  ? 160.383 186.766 206.155 1.00 10.51 ? 98  VAL C CG1 1 
ATOM   6867 C CG2 . VAL C 3 99  ? 158.081 186.895 205.229 1.00 10.51 ? 98  VAL C CG2 1 
ATOM   6868 N N   . PHE C 3 100 ? 162.246 188.135 203.692 1.00 9.16  ? 99  PHE C N   1 
ATOM   6869 C CA  . PHE C 3 100 ? 163.697 188.189 203.624 1.00 9.16  ? 99  PHE C CA  1 
ATOM   6870 C C   . PHE C 3 100 ? 164.269 188.690 204.942 1.00 9.16  ? 99  PHE C C   1 
ATOM   6871 O O   . PHE C 3 100 ? 163.567 189.282 205.764 1.00 9.16  ? 99  PHE C O   1 
ATOM   6872 C CB  . PHE C 3 100 ? 164.164 189.090 202.475 1.00 9.16  ? 99  PHE C CB  1 
ATOM   6873 C CG  . PHE C 3 100 ? 164.122 188.427 201.129 1.00 9.16  ? 99  PHE C CG  1 
ATOM   6874 C CD1 . PHE C 3 100 ? 162.978 188.461 200.360 1.00 9.16  ? 99  PHE C CD1 1 
ATOM   6875 C CD2 . PHE C 3 100 ? 165.225 187.768 200.636 1.00 9.16  ? 99  PHE C CD2 1 
ATOM   6876 C CE1 . PHE C 3 100 ? 162.939 187.850 199.130 1.00 9.16  ? 99  PHE C CE1 1 
ATOM   6877 C CE2 . PHE C 3 100 ? 165.187 187.155 199.410 1.00 9.16  ? 99  PHE C CE2 1 
ATOM   6878 C CZ  . PHE C 3 100 ? 164.044 187.196 198.658 1.00 9.16  ? 99  PHE C CZ  1 
ATOM   6879 N N   . ASP C 3 101 ? 165.561 188.446 205.134 1.00 16.32 ? 100 ASP C N   1 
ATOM   6880 C CA  . ASP C 3 101 ? 166.286 188.864 206.329 1.00 16.32 ? 100 ASP C CA  1 
ATOM   6881 C C   . ASP C 3 101 ? 167.559 189.599 205.945 1.00 16.32 ? 100 ASP C C   1 
ATOM   6882 O O   . ASP C 3 101 ? 168.642 189.329 206.464 1.00 16.32 ? 100 ASP C O   1 
ATOM   6883 C CB  . ASP C 3 101 ? 166.617 187.680 207.224 1.00 16.32 ? 100 ASP C CB  1 
ATOM   6884 C CG  . ASP C 3 101 ? 165.391 187.079 207.861 1.00 16.32 ? 100 ASP C CG  1 
ATOM   6885 O OD1 . ASP C 3 101 ? 164.416 187.823 208.084 1.00 16.32 ? 100 ASP C OD1 1 
ATOM   6886 O OD2 . ASP C 3 101 ? 165.406 185.868 208.157 1.00 16.32 ? 100 ASP C OD2 1 
ATOM   6887 N N   . VAL C 3 102 ? 167.431 190.553 205.023 1.00 13.98 ? 101 VAL C N   1 
ATOM   6888 C CA  . VAL C 3 102 ? 168.591 191.250 204.496 1.00 13.98 ? 101 VAL C CA  1 
ATOM   6889 C C   . VAL C 3 102 ? 169.362 191.952 205.609 1.00 13.98 ? 101 VAL C C   1 
ATOM   6890 O O   . VAL C 3 102 ? 168.843 192.215 206.699 1.00 13.98 ? 101 VAL C O   1 
ATOM   6891 C CB  . VAL C 3 102 ? 168.146 192.252 203.425 1.00 13.98 ? 101 VAL C CB  1 
ATOM   6892 C CG1 . VAL C 3 102 ? 167.486 191.526 202.292 1.00 13.98 ? 101 VAL C CG1 1 
ATOM   6893 C CG2 . VAL C 3 102 ? 167.177 193.220 204.023 1.00 13.98 ? 101 VAL C CG2 1 
ATOM   6894 N N   . GLU C 3 103 ? 170.632 192.245 205.327 1.00 16.49 ? 102 GLU C N   1 
ATOM   6895 C CA  . GLU C 3 103 ? 171.496 192.938 206.282 1.00 16.49 ? 102 GLU C CA  1 
ATOM   6896 C C   . GLU C 3 103 ? 172.547 193.707 205.486 1.00 16.49 ? 102 GLU C C   1 
ATOM   6897 O O   . GLU C 3 103 ? 173.534 193.122 205.037 1.00 16.49 ? 102 GLU C O   1 
ATOM   6898 C CB  . GLU C 3 103 ? 172.140 191.958 207.252 1.00 16.49 ? 102 GLU C CB  1 
ATOM   6899 N N   . LEU C 3 104 ? 172.330 195.008 205.320 1.00 23.54 ? 103 LEU C N   1 
ATOM   6900 C CA  . LEU C 3 104 ? 173.287 195.844 204.610 1.00 23.54 ? 103 LEU C CA  1 
ATOM   6901 C C   . LEU C 3 104 ? 174.557 196.003 205.435 1.00 23.54 ? 103 LEU C C   1 
ATOM   6902 O O   . LEU C 3 104 ? 174.496 196.333 206.621 1.00 23.54 ? 103 LEU C O   1 
ATOM   6903 C CB  . LEU C 3 104 ? 172.669 197.208 204.313 1.00 23.54 ? 103 LEU C CB  1 
ATOM   6904 C CG  . LEU C 3 104 ? 173.564 198.279 203.697 1.00 23.54 ? 103 LEU C CG  1 
ATOM   6905 C CD1 . LEU C 3 104 ? 174.325 197.721 202.521 1.00 23.54 ? 103 LEU C CD1 1 
ATOM   6906 C CD2 . LEU C 3 104 ? 172.731 199.462 203.257 1.00 23.54 ? 103 LEU C CD2 1 
ATOM   6907 N N   . LEU C 3 105 ? 175.709 195.775 204.807 1.00 27.41 ? 104 LEU C N   1 
ATOM   6908 C CA  . LEU C 3 105 ? 176.989 195.812 205.505 1.00 27.41 ? 104 LEU C CA  1 
ATOM   6909 C C   . LEU C 3 105 ? 177.901 196.925 205.017 1.00 27.41 ? 104 LEU C C   1 
ATOM   6910 O O   . LEU C 3 105 ? 178.425 197.691 205.833 1.00 27.41 ? 104 LEU C O   1 
ATOM   6911 C CB  . LEU C 3 105 ? 177.709 194.463 205.366 1.00 27.41 ? 104 LEU C CB  1 
ATOM   6912 C CG  . LEU C 3 105 ? 176.901 193.201 205.658 1.00 27.41 ? 104 LEU C CG  1 
ATOM   6913 C CD1 . LEU C 3 105 ? 177.615 191.984 205.090 1.00 27.41 ? 104 LEU C CD1 1 
ATOM   6914 C CD2 . LEU C 3 105 ? 176.660 193.046 207.152 1.00 27.41 ? 104 LEU C CD2 1 
ATOM   6915 N N   . LYS C 3 106 ? 178.120 197.032 203.708 1.00 32.14 ? 105 LYS C N   1 
ATOM   6916 C CA  . LYS C 3 106 ? 179.031 198.021 203.153 1.00 32.14 ? 105 LYS C CA  1 
ATOM   6917 C C   . LYS C 3 106 ? 178.419 198.622 201.898 1.00 32.14 ? 105 LYS C C   1 
ATOM   6918 O O   . LYS C 3 106 ? 177.422 198.130 201.367 1.00 32.14 ? 105 LYS C O   1 
ATOM   6919 C CB  . LYS C 3 106 ? 180.397 197.411 202.822 1.00 32.14 ? 105 LYS C CB  1 
ATOM   6920 C CG  . LYS C 3 106 ? 181.291 197.159 204.022 1.00 32.14 ? 105 LYS C CG  1 
ATOM   6921 C CD  . LYS C 3 106 ? 182.379 196.139 203.694 1.00 32.14 ? 105 LYS C CD  1 
ATOM   6922 C CE  . LYS C 3 106 ? 182.799 196.205 202.231 1.00 32.14 ? 105 LYS C CE  1 
ATOM   6923 N NZ  . LYS C 3 106 ? 183.353 194.912 201.750 1.00 32.14 ? 105 LYS C NZ  1 
ATOM   6924 N N   . LEU C 3 107 ? 179.031 199.704 201.427 1.00 33.00 ? 106 LEU C N   1 
ATOM   6925 C CA  . LEU C 3 107 ? 178.643 200.352 200.182 1.00 33.00 ? 106 LEU C CA  1 
ATOM   6926 C C   . LEU C 3 107 ? 179.899 200.668 199.388 1.00 33.00 ? 106 LEU C C   1 
ATOM   6927 O O   . LEU C 3 107 ? 180.876 201.176 199.947 1.00 33.00 ? 106 LEU C O   1 
ATOM   6928 C CB  . LEU C 3 107 ? 177.840 201.630 200.442 1.00 33.00 ? 106 LEU C CB  1 
ATOM   6929 C CG  . LEU C 3 107 ? 176.468 201.487 201.103 1.00 33.00 ? 106 LEU C CG  1 
ATOM   6930 C CD1 . LEU C 3 107 ? 176.586 201.523 202.610 1.00 33.00 ? 106 LEU C CD1 1 
ATOM   6931 C CD2 . LEU C 3 107 ? 175.543 202.584 200.618 1.00 33.00 ? 106 LEU C CD2 1 
ATOM   6932 N N   . GLU C 3 108 ? 179.874 200.373 198.094 1.00 36.88 ? 107 GLU C N   1 
ATOM   6933 C CA  . GLU C 3 108 ? 181.043 200.589 197.253 1.00 36.88 ? 107 GLU C CA  1 
ATOM   6934 C C   . GLU C 3 108 ? 180.690 201.355 195.984 1.00 36.88 ? 107 GLU C C   1 
ATOM   6935 C CB  . GLU C 3 108 ? 181.693 199.253 196.895 1.00 36.88 ? 107 GLU C CB  1 
ATOM   6936 C CG  . GLU C 3 108 ? 182.267 198.506 198.089 1.00 36.88 ? 107 GLU C CG  1 
ATOM   6937 C CD  . GLU C 3 108 ? 183.155 197.344 197.685 1.00 36.88 ? 107 GLU C CD  1 
ATOM   6938 O OE1 . GLU C 3 108 ? 183.408 197.178 196.473 1.00 36.88 ? 107 GLU C OE1 1 
ATOM   6939 O OE2 . GLU C 3 108 ? 183.597 196.595 198.581 1.00 36.88 ? 107 GLU C OE2 1 
ATOM   6940 O OXT . GLU C 3 108 ? 181.554 201.965 195.353 1.00 36.88 ? 107 GLU C OXT 1 
HETATM 6941 O OAC . E5E D 4 .   ? 164.311 161.196 124.353 1.00 10.35 ? 501 E5E A OAC 1 
HETATM 6942 C CAJ . E5E D 4 .   ? 165.131 161.546 125.470 1.00 10.35 ? 501 E5E A CAJ 1 
HETATM 6943 C CAG . E5E D 4 .   ? 166.479 161.318 125.408 1.00 10.35 ? 501 E5E A CAG 1 
HETATM 6944 C CAI . E5E D 4 .   ? 164.573 162.116 126.606 1.00 10.35 ? 501 E5E A CAI 1 
HETATM 6945 O OAB . E5E D 4 .   ? 163.170 162.354 126.676 1.00 10.35 ? 501 E5E A OAB 1 
HETATM 6946 C CAE . E5E D 4 .   ? 165.385 162.463 127.709 1.00 10.35 ? 501 E5E A CAE 1 
HETATM 6947 C CAF . E5E D 4 .   ? 166.722 162.242 127.650 1.00 10.35 ? 501 E5E A CAF 1 
HETATM 6948 C CAK . E5E D 4 .   ? 167.302 161.655 126.477 1.00 10.35 ? 501 E5E A CAK 1 
HETATM 6949 C CAL . E5E D 4 .   ? 168.779 161.377 126.381 1.00 10.35 ? 501 E5E A CAL 1 
HETATM 6950 O OAD . E5E D 4 .   ? 169.266 161.192 127.685 1.00 10.35 ? 501 E5E A OAD 1 
HETATM 6951 C CAH . E5E D 4 .   ? 168.920 160.019 125.578 1.00 10.35 ? 501 E5E A CAH 1 
HETATM 6952 N NAA . E5E D 4 .   ? 170.197 159.311 125.785 1.00 10.35 ? 501 E5E A NAA 1 
HETATM 6953 C C1  . FK5 E 5 .   ? 166.327 188.519 192.653 1.00 17.00 ? 201 FK5 C C1  1 
HETATM 6954 C C2  . FK5 E 5 .   ? 165.973 188.249 194.098 1.00 17.00 ? 201 FK5 C C2  1 
HETATM 6955 C C3  . FK5 E 5 .   ? 166.351 189.443 194.961 1.00 17.00 ? 201 FK5 C C3  1 
HETATM 6956 C C4  . FK5 E 5 .   ? 167.854 189.541 195.147 1.00 17.00 ? 201 FK5 C C4  1 
HETATM 6957 C C5  . FK5 E 5 .   ? 168.388 188.281 195.797 1.00 17.00 ? 201 FK5 C C5  1 
HETATM 6958 C C6  . FK5 E 5 .   ? 168.059 187.066 194.951 1.00 17.00 ? 201 FK5 C C6  1 
HETATM 6959 C C8  . FK5 E 5 .   ? 165.887 185.979 194.888 1.00 17.00 ? 201 FK5 C C8  1 
HETATM 6960 C C9  . FK5 E 5 .   ? 166.448 184.803 195.387 1.00 17.00 ? 201 FK5 C C9  1 
HETATM 6961 C C10 . FK5 E 5 .   ? 166.958 183.702 194.462 1.00 17.00 ? 201 FK5 C C10 1 
HETATM 6962 C C11 . FK5 E 5 .   ? 165.979 183.525 193.308 1.00 17.00 ? 201 FK5 C C11 1 
HETATM 6963 C C12 . FK5 E 5 .   ? 166.579 182.735 192.154 1.00 17.00 ? 201 FK5 C C12 1 
HETATM 6964 C C13 . FK5 E 5 .   ? 167.992 183.196 191.853 1.00 17.00 ? 201 FK5 C C13 1 
HETATM 6965 C C14 . FK5 E 5 .   ? 168.800 183.090 193.132 1.00 17.00 ? 201 FK5 C C14 1 
HETATM 6966 C C15 . FK5 E 5 .   ? 170.292 183.358 192.951 1.00 17.00 ? 201 FK5 C C15 1 
HETATM 6967 C C16 . FK5 E 5 .   ? 170.545 184.693 192.266 1.00 17.00 ? 201 FK5 C C16 1 
HETATM 6968 C C17 . FK5 E 5 .   ? 171.970 185.198 192.475 1.00 17.00 ? 201 FK5 C C17 1 
HETATM 6969 C C18 . FK5 E 5 .   ? 172.924 184.572 191.467 1.00 17.00 ? 201 FK5 C C18 1 
HETATM 6970 C C19 . FK5 E 5 .   ? 172.747 185.185 190.100 1.00 17.00 ? 201 FK5 C C19 1 
HETATM 6971 C C20 . FK5 E 5 .   ? 171.850 184.536 189.132 1.00 17.00 ? 201 FK5 C C20 1 
HETATM 6972 C C21 . FK5 E 5 .   ? 171.419 185.172 187.854 1.00 17.00 ? 201 FK5 C C21 1 
HETATM 6973 C C22 . FK5 E 5 .   ? 170.250 186.057 188.133 1.00 17.00 ? 201 FK5 C C22 1 
HETATM 6974 C C23 . FK5 E 5 .   ? 170.452 187.523 188.437 1.00 17.00 ? 201 FK5 C C23 1 
HETATM 6975 C C24 . FK5 E 5 .   ? 169.150 188.189 188.863 1.00 17.00 ? 201 FK5 C C24 1 
HETATM 6976 C C25 . FK5 E 5 .   ? 168.870 187.989 190.341 1.00 17.00 ? 201 FK5 C C25 1 
HETATM 6977 C C26 . FK5 E 5 .   ? 167.429 188.310 190.718 1.00 17.00 ? 201 FK5 C C26 1 
HETATM 6978 C C27 . FK5 E 5 .   ? 166.480 187.657 189.764 1.00 17.00 ? 201 FK5 C C27 1 
HETATM 6979 C C28 . FK5 E 5 .   ? 165.784 188.462 188.749 1.00 17.00 ? 201 FK5 C C28 1 
HETATM 6980 C C29 . FK5 E 5 .   ? 164.503 187.995 188.132 1.00 17.00 ? 201 FK5 C C29 1 
HETATM 6981 C C30 . FK5 E 5 .   ? 163.572 189.179 187.914 1.00 17.00 ? 201 FK5 C C30 1 
HETATM 6982 C C31 . FK5 E 5 .   ? 162.243 188.690 187.351 1.00 17.00 ? 201 FK5 C C31 1 
HETATM 6983 C C32 . FK5 E 5 .   ? 162.426 187.884 186.072 1.00 17.00 ? 201 FK5 C C32 1 
HETATM 6984 C C33 . FK5 E 5 .   ? 163.463 186.783 186.242 1.00 17.00 ? 201 FK5 C C33 1 
HETATM 6985 C C34 . FK5 E 5 .   ? 164.765 187.355 186.779 1.00 17.00 ? 201 FK5 C C34 1 
HETATM 6986 C C35 . FK5 E 5 .   ? 164.712 182.841 193.802 1.00 17.00 ? 201 FK5 C C35 1 
HETATM 6987 C C36 . FK5 E 5 .   ? 172.444 184.913 193.890 1.00 17.00 ? 201 FK5 C C36 1 
HETATM 6988 C C37 . FK5 E 5 .   ? 173.498 186.429 189.742 1.00 17.00 ? 201 FK5 C C37 1 
HETATM 6989 C C38 . FK5 E 5 .   ? 170.901 184.069 186.950 1.00 17.00 ? 201 FK5 C C38 1 
HETATM 6990 C C39 . FK5 E 5 .   ? 171.874 183.785 185.836 1.00 17.00 ? 201 FK5 C C39 1 
HETATM 6991 C C40 . FK5 E 5 .   ? 173.061 182.959 186.070 1.00 17.00 ? 201 FK5 C C40 1 
HETATM 6992 C C41 . FK5 E 5 .   ? 169.820 188.868 191.137 1.00 17.00 ? 201 FK5 C C41 1 
HETATM 6993 C C42 . FK5 E 5 .   ? 166.245 186.183 189.854 1.00 17.00 ? 201 FK5 C C42 1 
HETATM 6994 C C43 . FK5 E 5 .   ? 168.013 182.750 189.580 1.00 17.00 ? 201 FK5 C C43 1 
HETATM 6995 C C44 . FK5 E 5 .   ? 171.480 181.335 192.984 1.00 17.00 ? 201 FK5 C C44 1 
HETATM 6996 C C45 . FK5 E 5 .   ? 160.415 189.929 188.087 1.00 17.00 ? 201 FK5 C C45 1 
HETATM 6997 N N7  . FK5 E 5 .   ? 166.626 187.056 194.650 1.00 17.00 ? 201 FK5 C N7  1 
HETATM 6998 O O1  . FK5 E 5 .   ? 167.179 187.841 192.029 1.00 17.00 ? 201 FK5 C O1  1 
HETATM 6999 O O2  . FK5 E 5 .   ? 165.679 189.569 191.970 1.00 17.00 ? 201 FK5 C O2  1 
HETATM 7000 O O3  . FK5 E 5 .   ? 164.502 186.060 194.649 1.00 17.00 ? 201 FK5 C O3  1 
HETATM 7001 O O4  . FK5 E 5 .   ? 166.530 184.623 196.780 1.00 17.00 ? 201 FK5 C O4  1 
HETATM 7002 O O5  . FK5 E 5 .   ? 168.253 184.041 194.011 1.00 17.00 ? 201 FK5 C O5  1 
HETATM 7003 O O6  . FK5 E 5 .   ? 167.027 182.455 195.194 1.00 17.00 ? 201 FK5 C O6  1 
HETATM 7004 O O7  . FK5 E 5 .   ? 168.520 182.379 190.842 1.00 17.00 ? 201 FK5 C O7  1 
HETATM 7005 O O8  . FK5 E 5 .   ? 170.875 182.327 192.185 1.00 17.00 ? 201 FK5 C O8  1 
HETATM 7006 O O9  . FK5 E 5 .   ? 168.956 185.504 188.097 1.00 17.00 ? 201 FK5 C O9  1 
HETATM 7007 O O10 . FK5 E 5 .   ? 169.263 189.571 188.628 1.00 17.00 ? 201 FK5 C O10 1 
HETATM 7008 O O11 . FK5 E 5 .   ? 161.403 189.790 187.092 1.00 17.00 ? 201 FK5 C O11 1 
HETATM 7009 O O12 . FK5 E 5 .   ? 161.189 187.300 185.737 1.00 17.00 ? 201 FK5 C O12 1 
# 
