data_9CGG
# 
_entry.id   9CGG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CGG         pdb_00009cgg 10.2210/pdb9cgg/pdb 
WWPDB D_1000285465 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CGG 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 9CEI unspecified 
PDB . 9CFI unspecified 
PDB . 9CFM unspecified 
PDB . 9CFO unspecified 
PDB . 9CFQ unspecified 
PDB . 9CGA unspecified 
PDB . 9CGB unspecified 
PDB . 9CGD unspecified 
PDB . 9CGE unspecified 
PDB . 9CGF unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              mwilson13@unl.edu 
_pdbx_contact_author.name_first         Mark 
_pdbx_contact_author.name_last          Wilson 
_pdbx_contact_author.name_mi            A 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6317-900X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zielinski, K.'  1  ? 
'Dolamore, C.'   2  ? 
'Dalton, K.'     3  ? 
'Meisburger, S.' 4  ? 
'Smith, N.'      5  ? 
'Termini, J.'    6  ? 
'Henning, R.'    7  ? 
'Srajer, V.'     8  ? 
'Hekstra, D.'    9  ? 
'Pollack, L.'    10 ? 
'Wilson, M.A.'   11 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.07.19.604369 
_citation.pdbx_database_id_PubMed   39071394 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zielinski, K.A.' 1  ?                   
primary 'Dolamore, C.'    2  ?                   
primary 'Dalton, K.M.'    3  ?                   
primary 'Smith, N.'       4  ?                   
primary 'Termini, J.'     5  ?                   
primary 'Henning, R.'     6  ?                   
primary 'Srajer, V.'      7  ?                   
primary 'Hekstra, D.R.'   8  ?                   
primary 'Pollack, L.'     9  0000-0002-9366-4396 
primary 'Wilson, M.A.'    10 0000-0001-6317-900X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Parkinson disease protein 7' 20271.391 1   3.1.2.-,3.5.1.-,3.5.1.124 ? ? ? 
2 water   nat water                         18.015    113 ?                         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'Maillard deglycase,Oncogene DJ1,Parkinsonism-associated deglycase,Protein DJ-1,DJ-1,Protein/nucleic acid deglycase DJ-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;GSHMASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNL
GAQNLSESAAVKEILKEQENRKGLIAAI(A1A7V)AGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGL
ILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GSHMASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNL
GAQNLSESAAVKEILKEQENRKGLIAAIXAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRG
PGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY   n 
1 2   SER   n 
1 3   HIS   n 
1 4   MET   n 
1 5   ALA   n 
1 6   SER   n 
1 7   LYS   n 
1 8   ARG   n 
1 9   ALA   n 
1 10  LEU   n 
1 11  VAL   n 
1 12  ILE   n 
1 13  LEU   n 
1 14  ALA   n 
1 15  LYS   n 
1 16  GLY   n 
1 17  ALA   n 
1 18  GLU   n 
1 19  GLU   n 
1 20  MET   n 
1 21  GLU   n 
1 22  THR   n 
1 23  VAL   n 
1 24  ILE   n 
1 25  PRO   n 
1 26  VAL   n 
1 27  ASP   n 
1 28  VAL   n 
1 29  MET   n 
1 30  ARG   n 
1 31  ARG   n 
1 32  ALA   n 
1 33  GLY   n 
1 34  ILE   n 
1 35  LYS   n 
1 36  VAL   n 
1 37  THR   n 
1 38  VAL   n 
1 39  ALA   n 
1 40  GLY   n 
1 41  LEU   n 
1 42  ALA   n 
1 43  GLY   n 
1 44  LYS   n 
1 45  ASP   n 
1 46  PRO   n 
1 47  VAL   n 
1 48  GLN   n 
1 49  CYS   n 
1 50  SER   n 
1 51  ARG   n 
1 52  ASP   n 
1 53  VAL   n 
1 54  VAL   n 
1 55  ILE   n 
1 56  CYS   n 
1 57  PRO   n 
1 58  ASP   n 
1 59  ALA   n 
1 60  SER   n 
1 61  LEU   n 
1 62  GLU   n 
1 63  ASP   n 
1 64  ALA   n 
1 65  LYS   n 
1 66  LYS   n 
1 67  GLU   n 
1 68  GLY   n 
1 69  PRO   n 
1 70  TYR   n 
1 71  ASP   n 
1 72  VAL   n 
1 73  VAL   n 
1 74  VAL   n 
1 75  LEU   n 
1 76  PRO   n 
1 77  GLY   n 
1 78  GLY   n 
1 79  ASN   n 
1 80  LEU   n 
1 81  GLY   n 
1 82  ALA   n 
1 83  GLN   n 
1 84  ASN   n 
1 85  LEU   n 
1 86  SER   n 
1 87  GLU   n 
1 88  SER   n 
1 89  ALA   n 
1 90  ALA   n 
1 91  VAL   n 
1 92  LYS   n 
1 93  GLU   n 
1 94  ILE   n 
1 95  LEU   n 
1 96  LYS   n 
1 97  GLU   n 
1 98  GLN   n 
1 99  GLU   n 
1 100 ASN   n 
1 101 ARG   n 
1 102 LYS   n 
1 103 GLY   n 
1 104 LEU   n 
1 105 ILE   n 
1 106 ALA   n 
1 107 ALA   n 
1 108 ILE   n 
1 109 A1A7V n 
1 110 ALA   n 
1 111 GLY   n 
1 112 PRO   n 
1 113 THR   n 
1 114 ALA   n 
1 115 LEU   n 
1 116 LEU   n 
1 117 ALA   n 
1 118 HIS   n 
1 119 GLU   n 
1 120 ILE   n 
1 121 GLY   n 
1 122 PHE   n 
1 123 GLY   n 
1 124 SER   n 
1 125 LYS   n 
1 126 VAL   n 
1 127 THR   n 
1 128 THR   n 
1 129 HIS   n 
1 130 PRO   n 
1 131 LEU   n 
1 132 ALA   n 
1 133 LYS   n 
1 134 ASP   n 
1 135 LYS   n 
1 136 MET   n 
1 137 MET   n 
1 138 ASN   n 
1 139 GLY   n 
1 140 GLY   n 
1 141 HIS   n 
1 142 TYR   n 
1 143 THR   n 
1 144 TYR   n 
1 145 SER   n 
1 146 GLU   n 
1 147 ASN   n 
1 148 ARG   n 
1 149 VAL   n 
1 150 GLU   n 
1 151 LYS   n 
1 152 ASP   n 
1 153 GLY   n 
1 154 LEU   n 
1 155 ILE   n 
1 156 LEU   n 
1 157 THR   n 
1 158 SER   n 
1 159 ARG   n 
1 160 GLY   n 
1 161 PRO   n 
1 162 GLY   n 
1 163 THR   n 
1 164 SER   n 
1 165 PHE   n 
1 166 GLU   n 
1 167 PHE   n 
1 168 ALA   n 
1 169 LEU   n 
1 170 ALA   n 
1 171 ILE   n 
1 172 VAL   n 
1 173 GLU   n 
1 174 ALA   n 
1 175 LEU   n 
1 176 ASN   n 
1 177 GLY   n 
1 178 LYS   n 
1 179 GLU   n 
1 180 VAL   n 
1 181 ALA   n 
1 182 ALA   n 
1 183 GLN   n 
1 184 VAL   n 
1 185 LYS   n 
1 186 ALA   n 
1 187 PRO   n 
1 188 LEU   n 
1 189 VAL   n 
1 190 LEU   n 
1 191 LYS   n 
1 192 ASP   n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   192 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PARK7 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pET15b 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1A7V 'L-peptide linking' n S-lactoyl-L-cysteine 'S-[(2S)-2-hydroxypropanoyl]-L-cysteine' 'C6 H11 N O4 S'  193.221 
ALA   'L-peptide linking' y ALANINE              ?                                        'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE             ?                                        'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE           ?                                        'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'      ?                                        'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE             ?                                        'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE            ?                                        'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'      ?                                        'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE              ?                                        'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE            ?                                        'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                ?                                        'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE           ?                                        'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE              ?                                        'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE               ?                                        'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE           ?                                        'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE        ?                                        'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE              ?                                        'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE               ?                                        'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE            ?                                        'C4 H9 N O3'     119.119 
TYR   'L-peptide linking' y TYROSINE             ?                                        'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE               ?                                        'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY   1   -2  ?   ?     ?   A . n 
A 1 2   SER   2   -1  ?   ?     ?   A . n 
A 1 3   HIS   3   0   ?   ?     ?   A . n 
A 1 4   MET   4   1   ?   ?     ?   A . n 
A 1 5   ALA   5   2   2   ALA   ALA A . n 
A 1 6   SER   6   3   3   SER   SER A . n 
A 1 7   LYS   7   4   4   LYS   LYS A . n 
A 1 8   ARG   8   5   5   ARG   ARG A . n 
A 1 9   ALA   9   6   6   ALA   ALA A . n 
A 1 10  LEU   10  7   7   LEU   LEU A . n 
A 1 11  VAL   11  8   8   VAL   VAL A . n 
A 1 12  ILE   12  9   9   ILE   ILE A . n 
A 1 13  LEU   13  10  10  LEU   LEU A . n 
A 1 14  ALA   14  11  11  ALA   ALA A . n 
A 1 15  LYS   15  12  12  LYS   LYS A . n 
A 1 16  GLY   16  13  13  GLY   GLY A . n 
A 1 17  ALA   17  14  14  ALA   ALA A . n 
A 1 18  GLU   18  15  15  GLU   GLU A . n 
A 1 19  GLU   19  16  16  GLU   GLU A . n 
A 1 20  MET   20  17  17  MET   MET A . n 
A 1 21  GLU   21  18  18  GLU   GLU A . n 
A 1 22  THR   22  19  19  THR   THR A . n 
A 1 23  VAL   23  20  20  VAL   VAL A . n 
A 1 24  ILE   24  21  21  ILE   ILE A . n 
A 1 25  PRO   25  22  22  PRO   PRO A . n 
A 1 26  VAL   26  23  23  VAL   VAL A . n 
A 1 27  ASP   27  24  24  ASP   ASP A . n 
A 1 28  VAL   28  25  25  VAL   VAL A . n 
A 1 29  MET   29  26  26  MET   MET A . n 
A 1 30  ARG   30  27  27  ARG   ARG A . n 
A 1 31  ARG   31  28  28  ARG   ARG A . n 
A 1 32  ALA   32  29  29  ALA   ALA A . n 
A 1 33  GLY   33  30  30  GLY   GLY A . n 
A 1 34  ILE   34  31  31  ILE   ILE A . n 
A 1 35  LYS   35  32  32  LYS   LYS A . n 
A 1 36  VAL   36  33  33  VAL   VAL A . n 
A 1 37  THR   37  34  34  THR   THR A . n 
A 1 38  VAL   38  35  35  VAL   VAL A . n 
A 1 39  ALA   39  36  36  ALA   ALA A . n 
A 1 40  GLY   40  37  37  GLY   GLY A . n 
A 1 41  LEU   41  38  38  LEU   LEU A . n 
A 1 42  ALA   42  39  39  ALA   ALA A . n 
A 1 43  GLY   43  40  40  GLY   GLY A . n 
A 1 44  LYS   44  41  41  LYS   LYS A . n 
A 1 45  ASP   45  42  42  ASP   ASP A . n 
A 1 46  PRO   46  43  43  PRO   PRO A . n 
A 1 47  VAL   47  44  44  VAL   VAL A . n 
A 1 48  GLN   48  45  45  GLN   GLN A . n 
A 1 49  CYS   49  46  46  CYS   CYS A . n 
A 1 50  SER   50  47  47  SER   SER A . n 
A 1 51  ARG   51  48  48  ARG   ARG A . n 
A 1 52  ASP   52  49  49  ASP   ASP A . n 
A 1 53  VAL   53  50  50  VAL   VAL A . n 
A 1 54  VAL   54  51  51  VAL   VAL A . n 
A 1 55  ILE   55  52  52  ILE   ILE A . n 
A 1 56  CYS   56  53  53  CYS   CYS A . n 
A 1 57  PRO   57  54  54  PRO   PRO A . n 
A 1 58  ASP   58  55  55  ASP   ASP A . n 
A 1 59  ALA   59  56  56  ALA   ALA A . n 
A 1 60  SER   60  57  57  SER   SER A . n 
A 1 61  LEU   61  58  58  LEU   LEU A . n 
A 1 62  GLU   62  59  59  GLU   GLU A . n 
A 1 63  ASP   63  60  60  ASP   ASP A . n 
A 1 64  ALA   64  61  61  ALA   ALA A . n 
A 1 65  LYS   65  62  62  LYS   LYS A . n 
A 1 66  LYS   66  63  63  LYS   LYS A . n 
A 1 67  GLU   67  64  64  GLU   GLU A . n 
A 1 68  GLY   68  65  65  GLY   GLY A . n 
A 1 69  PRO   69  66  66  PRO   PRO A . n 
A 1 70  TYR   70  67  67  TYR   TYR A . n 
A 1 71  ASP   71  68  68  ASP   ASP A . n 
A 1 72  VAL   72  69  69  VAL   VAL A . n 
A 1 73  VAL   73  70  70  VAL   VAL A . n 
A 1 74  VAL   74  71  71  VAL   VAL A . n 
A 1 75  LEU   75  72  72  LEU   LEU A . n 
A 1 76  PRO   76  73  73  PRO   PRO A . n 
A 1 77  GLY   77  74  74  GLY   GLY A . n 
A 1 78  GLY   78  75  75  GLY   GLY A . n 
A 1 79  ASN   79  76  76  ASN   ASN A . n 
A 1 80  LEU   80  77  77  LEU   LEU A . n 
A 1 81  GLY   81  78  78  GLY   GLY A . n 
A 1 82  ALA   82  79  79  ALA   ALA A . n 
A 1 83  GLN   83  80  80  GLN   GLN A . n 
A 1 84  ASN   84  81  81  ASN   ASN A . n 
A 1 85  LEU   85  82  82  LEU   LEU A . n 
A 1 86  SER   86  83  83  SER   SER A . n 
A 1 87  GLU   87  84  84  GLU   GLU A . n 
A 1 88  SER   88  85  85  SER   SER A . n 
A 1 89  ALA   89  86  86  ALA   ALA A . n 
A 1 90  ALA   90  87  87  ALA   ALA A . n 
A 1 91  VAL   91  88  88  VAL   VAL A . n 
A 1 92  LYS   92  89  89  LYS   LYS A . n 
A 1 93  GLU   93  90  90  GLU   GLU A . n 
A 1 94  ILE   94  91  91  ILE   ILE A . n 
A 1 95  LEU   95  92  92  LEU   LEU A . n 
A 1 96  LYS   96  93  93  LYS   LYS A . n 
A 1 97  GLU   97  94  94  GLU   GLU A . n 
A 1 98  GLN   98  95  95  GLN   GLN A . n 
A 1 99  GLU   99  96  96  GLU   GLU A . n 
A 1 100 ASN   100 97  97  ASN   ASN A . n 
A 1 101 ARG   101 98  98  ARG   ARG A . n 
A 1 102 LYS   102 99  99  LYS   LYS A . n 
A 1 103 GLY   103 100 100 GLY   GLY A . n 
A 1 104 LEU   104 101 101 LEU   LEU A . n 
A 1 105 ILE   105 102 102 ILE   ILE A . n 
A 1 106 ALA   106 103 103 ALA   ALA A . n 
A 1 107 ALA   107 104 104 ALA   ALA A . n 
A 1 108 ILE   108 105 105 ILE   ILE A . n 
A 1 109 A1A7V 109 106 106 A1A7V CYS A . n 
A 1 110 ALA   110 107 107 ALA   ALA A . n 
A 1 111 GLY   111 108 108 GLY   GLY A . n 
A 1 112 PRO   112 109 109 PRO   PRO A . n 
A 1 113 THR   113 110 110 THR   THR A . n 
A 1 114 ALA   114 111 111 ALA   ALA A . n 
A 1 115 LEU   115 112 112 LEU   LEU A . n 
A 1 116 LEU   116 113 113 LEU   LEU A . n 
A 1 117 ALA   117 114 114 ALA   ALA A . n 
A 1 118 HIS   118 115 115 HIS   HIS A . n 
A 1 119 GLU   119 116 116 GLU   GLU A . n 
A 1 120 ILE   120 117 117 ILE   ILE A . n 
A 1 121 GLY   121 118 118 GLY   GLY A . n 
A 1 122 PHE   122 119 119 PHE   PHE A . n 
A 1 123 GLY   123 120 120 GLY   GLY A . n 
A 1 124 SER   124 121 121 SER   SER A . n 
A 1 125 LYS   125 122 122 LYS   LYS A . n 
A 1 126 VAL   126 123 123 VAL   VAL A . n 
A 1 127 THR   127 124 124 THR   THR A . n 
A 1 128 THR   128 125 125 THR   THR A . n 
A 1 129 HIS   129 126 126 HIS   HIS A . n 
A 1 130 PRO   130 127 127 PRO   PRO A . n 
A 1 131 LEU   131 128 128 LEU   LEU A . n 
A 1 132 ALA   132 129 129 ALA   ALA A . n 
A 1 133 LYS   133 130 130 LYS   LYS A . n 
A 1 134 ASP   134 131 131 ASP   ASP A . n 
A 1 135 LYS   135 132 132 LYS   LYS A . n 
A 1 136 MET   136 133 133 MET   MET A . n 
A 1 137 MET   137 134 134 MET   MET A . n 
A 1 138 ASN   138 135 135 ASN   ASN A . n 
A 1 139 GLY   139 136 136 GLY   GLY A . n 
A 1 140 GLY   140 137 137 GLY   GLY A . n 
A 1 141 HIS   141 138 138 HIS   HIS A . n 
A 1 142 TYR   142 139 139 TYR   TYR A . n 
A 1 143 THR   143 140 140 THR   THR A . n 
A 1 144 TYR   144 141 141 TYR   TYR A . n 
A 1 145 SER   145 142 142 SER   SER A . n 
A 1 146 GLU   146 143 143 GLU   GLU A . n 
A 1 147 ASN   147 144 144 ASN   ASN A . n 
A 1 148 ARG   148 145 145 ARG   ARG A . n 
A 1 149 VAL   149 146 146 VAL   VAL A . n 
A 1 150 GLU   150 147 147 GLU   GLU A . n 
A 1 151 LYS   151 148 148 LYS   LYS A . n 
A 1 152 ASP   152 149 149 ASP   ASP A . n 
A 1 153 GLY   153 150 150 GLY   GLY A . n 
A 1 154 LEU   154 151 151 LEU   LEU A . n 
A 1 155 ILE   155 152 152 ILE   ILE A . n 
A 1 156 LEU   156 153 153 LEU   LEU A . n 
A 1 157 THR   157 154 154 THR   THR A . n 
A 1 158 SER   158 155 155 SER   SER A . n 
A 1 159 ARG   159 156 156 ARG   ARG A . n 
A 1 160 GLY   160 157 157 GLY   GLY A . n 
A 1 161 PRO   161 158 158 PRO   PRO A . n 
A 1 162 GLY   162 159 159 GLY   GLY A . n 
A 1 163 THR   163 160 160 THR   THR A . n 
A 1 164 SER   164 161 161 SER   SER A . n 
A 1 165 PHE   165 162 162 PHE   PHE A . n 
A 1 166 GLU   166 163 163 GLU   GLU A . n 
A 1 167 PHE   167 164 164 PHE   PHE A . n 
A 1 168 ALA   168 165 165 ALA   ALA A . n 
A 1 169 LEU   169 166 166 LEU   LEU A . n 
A 1 170 ALA   170 167 167 ALA   ALA A . n 
A 1 171 ILE   171 168 168 ILE   ILE A . n 
A 1 172 VAL   172 169 169 VAL   VAL A . n 
A 1 173 GLU   173 170 170 GLU   GLU A . n 
A 1 174 ALA   174 171 171 ALA   ALA A . n 
A 1 175 LEU   175 172 172 LEU   LEU A . n 
A 1 176 ASN   176 173 173 ASN   ASN A . n 
A 1 177 GLY   177 174 174 GLY   GLY A . n 
A 1 178 LYS   178 175 175 LYS   LYS A . n 
A 1 179 GLU   179 176 176 GLU   GLU A . n 
A 1 180 VAL   180 177 177 VAL   VAL A . n 
A 1 181 ALA   181 178 178 ALA   ALA A . n 
A 1 182 ALA   182 179 179 ALA   ALA A . n 
A 1 183 GLN   183 180 180 GLN   GLN A . n 
A 1 184 VAL   184 181 181 VAL   VAL A . n 
A 1 185 LYS   185 182 182 LYS   LYS A . n 
A 1 186 ALA   186 183 183 ALA   ALA A . n 
A 1 187 PRO   187 184 184 PRO   PRO A . n 
A 1 188 LEU   188 185 185 LEU   LEU A . n 
A 1 189 VAL   189 186 186 VAL   VAL A . n 
A 1 190 LEU   190 187 187 LEU   LEU A . n 
A 1 191 LYS   191 188 188 LYS   LYS A . n 
A 1 192 ASP   192 189 189 ASP   ASP A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1A7V 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1A7V 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 HOH 1   301 79  HOH HOH A . 
B 2 HOH 2   302 4   HOH HOH A . 
B 2 HOH 3   303 93  HOH HOH A . 
B 2 HOH 4   304 23  HOH HOH A . 
B 2 HOH 5   305 61  HOH HOH A . 
B 2 HOH 6   306 6   HOH HOH A . 
B 2 HOH 7   307 87  HOH HOH A . 
B 2 HOH 8   308 5   HOH HOH A . 
B 2 HOH 9   309 29  HOH HOH A . 
B 2 HOH 10  310 25  HOH HOH A . 
B 2 HOH 11  311 3   HOH HOH A . 
B 2 HOH 12  312 104 HOH HOH A . 
B 2 HOH 13  313 69  HOH HOH A . 
B 2 HOH 14  314 15  HOH HOH A . 
B 2 HOH 15  315 10  HOH HOH A . 
B 2 HOH 16  316 28  HOH HOH A . 
B 2 HOH 17  317 37  HOH HOH A . 
B 2 HOH 18  318 115 HOH HOH A . 
B 2 HOH 19  319 49  HOH HOH A . 
B 2 HOH 20  320 71  HOH HOH A . 
B 2 HOH 21  321 1   HOH HOH A . 
B 2 HOH 22  322 9   HOH HOH A . 
B 2 HOH 23  323 14  HOH HOH A . 
B 2 HOH 24  324 110 HOH HOH A . 
B 2 HOH 25  325 70  HOH HOH A . 
B 2 HOH 26  326 58  HOH HOH A . 
B 2 HOH 27  327 21  HOH HOH A . 
B 2 HOH 28  328 36  HOH HOH A . 
B 2 HOH 29  329 44  HOH HOH A . 
B 2 HOH 30  330 53  HOH HOH A . 
B 2 HOH 31  331 26  HOH HOH A . 
B 2 HOH 32  332 12  HOH HOH A . 
B 2 HOH 33  333 113 HOH HOH A . 
B 2 HOH 34  334 62  HOH HOH A . 
B 2 HOH 35  335 77  HOH HOH A . 
B 2 HOH 36  336 97  HOH HOH A . 
B 2 HOH 37  337 33  HOH HOH A . 
B 2 HOH 38  338 55  HOH HOH A . 
B 2 HOH 39  339 72  HOH HOH A . 
B 2 HOH 40  340 11  HOH HOH A . 
B 2 HOH 41  341 98  HOH HOH A . 
B 2 HOH 42  342 35  HOH HOH A . 
B 2 HOH 43  343 19  HOH HOH A . 
B 2 HOH 44  344 81  HOH HOH A . 
B 2 HOH 45  345 7   HOH HOH A . 
B 2 HOH 46  346 91  HOH HOH A . 
B 2 HOH 47  347 30  HOH HOH A . 
B 2 HOH 48  348 22  HOH HOH A . 
B 2 HOH 49  349 8   HOH HOH A . 
B 2 HOH 50  350 41  HOH HOH A . 
B 2 HOH 51  351 54  HOH HOH A . 
B 2 HOH 52  352 47  HOH HOH A . 
B 2 HOH 53  353 82  HOH HOH A . 
B 2 HOH 54  354 27  HOH HOH A . 
B 2 HOH 55  355 65  HOH HOH A . 
B 2 HOH 56  356 20  HOH HOH A . 
B 2 HOH 57  357 48  HOH HOH A . 
B 2 HOH 58  358 17  HOH HOH A . 
B 2 HOH 59  359 73  HOH HOH A . 
B 2 HOH 60  360 109 HOH HOH A . 
B 2 HOH 61  361 16  HOH HOH A . 
B 2 HOH 62  362 67  HOH HOH A . 
B 2 HOH 63  363 24  HOH HOH A . 
B 2 HOH 64  364 31  HOH HOH A . 
B 2 HOH 65  365 86  HOH HOH A . 
B 2 HOH 66  366 56  HOH HOH A . 
B 2 HOH 67  367 52  HOH HOH A . 
B 2 HOH 68  368 32  HOH HOH A . 
B 2 HOH 69  369 68  HOH HOH A . 
B 2 HOH 70  370 2   HOH HOH A . 
B 2 HOH 71  371 13  HOH HOH A . 
B 2 HOH 72  372 76  HOH HOH A . 
B 2 HOH 73  373 42  HOH HOH A . 
B 2 HOH 74  374 39  HOH HOH A . 
B 2 HOH 75  375 75  HOH HOH A . 
B 2 HOH 76  376 78  HOH HOH A . 
B 2 HOH 77  377 116 HOH HOH A . 
B 2 HOH 78  378 64  HOH HOH A . 
B 2 HOH 79  379 106 HOH HOH A . 
B 2 HOH 80  380 38  HOH HOH A . 
B 2 HOH 81  381 50  HOH HOH A . 
B 2 HOH 82  382 34  HOH HOH A . 
B 2 HOH 83  383 84  HOH HOH A . 
B 2 HOH 84  384 63  HOH HOH A . 
B 2 HOH 85  385 96  HOH HOH A . 
B 2 HOH 86  386 45  HOH HOH A . 
B 2 HOH 87  387 100 HOH HOH A . 
B 2 HOH 88  388 92  HOH HOH A . 
B 2 HOH 89  389 80  HOH HOH A . 
B 2 HOH 90  390 57  HOH HOH A . 
B 2 HOH 91  391 40  HOH HOH A . 
B 2 HOH 92  392 83  HOH HOH A . 
B 2 HOH 93  393 111 HOH HOH A . 
B 2 HOH 94  394 18  HOH HOH A . 
B 2 HOH 95  395 51  HOH HOH A . 
B 2 HOH 96  396 59  HOH HOH A . 
B 2 HOH 97  397 103 HOH HOH A . 
B 2 HOH 98  398 66  HOH HOH A . 
B 2 HOH 99  399 46  HOH HOH A . 
B 2 HOH 100 400 108 HOH HOH A . 
B 2 HOH 101 401 114 HOH HOH A . 
B 2 HOH 102 402 85  HOH HOH A . 
B 2 HOH 103 403 90  HOH HOH A . 
B 2 HOH 104 404 88  HOH HOH A . 
B 2 HOH 105 405 74  HOH HOH A . 
B 2 HOH 106 406 102 HOH HOH A . 
B 2 HOH 107 407 43  HOH HOH A . 
B 2 HOH 108 408 112 HOH HOH A . 
B 2 HOH 109 409 107 HOH HOH A . 
B 2 HOH 110 410 95  HOH HOH A . 
B 2 HOH 111 411 105 HOH HOH A . 
B 2 HOH 112 412 89  HOH HOH A . 
B 2 HOH 113 413 94  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX       ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? Precognition ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL     ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX       ? ? ? 1.19.2_4158 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CGG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     76.030 
_cell.length_a_esd                 ? 
_cell.length_b                     76.030 
_cell.length_b_esd                 ? 
_cell.length_c                     76.140 
_cell.length_c_esd                 ? 
_cell.volume                       381165.412 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CGG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                152 
_symmetry.space_group_name_Hall            
;P 31 2"
;
_symmetry.space_group_name_H-M             'P 31 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CGG 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.15 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          60.89 
_exptl_crystal.description                  '20-25 micron microcrystals' 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'RAYONIX MX340-HS' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-11-12 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   L 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             LAUE 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
loop_
_diffrn_radiation_wavelength.id 
_diffrn_radiation_wavelength.wavelength 
_diffrn_radiation_wavelength.wt 
1 1.240 1.0 
2 1.016 1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 14-ID-B' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.240-1.016 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   14-ID-B 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          27.93 
_reflns.entry_id                                       9CGG 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.77 
_reflns.d_resolution_low                               65.84 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     24993 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.98 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                60.65 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          3.64 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.98 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   0.1375 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.77 
_reflns_shell.d_res_low                                     1.80 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2428 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               58.4 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.04 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.70 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               34.18 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CGG 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.01 
_refine.ls_d_res_low                             32.96 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     17196 
_refine.ls_number_reflns_R_free                  861 
_refine.ls_number_reflns_R_work                  16335 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.05 
_refine.ls_percent_reflns_R_free                 5.01 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1631 
_refine.ls_R_factor_R_free                       0.1821 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1620 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'FOURIER SYNTHESIS' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 21.6101 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2583 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.01 
_refine_hist.d_res_low                        32.96 
_refine_hist.number_atoms_solvent             113 
_refine_hist.number_atoms_total               1501 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1383 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         5 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0019  ? 1459 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5099  ? 1977 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0434  ? 233  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0031  ? 260  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.0630 ? 562  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.01 2.14  . . 152 2653 99.08 . . . . 0.2849 . . . . . . . . . . . 0.3057 
'X-RAY DIFFRACTION' 2.14 2.30  . . 154 2701 99.30 . . . . 0.2357 . . . . . . . . . . . 0.3021 
'X-RAY DIFFRACTION' 2.30 2.53  . . 135 2702 99.09 . . . . 0.1988 . . . . . . . . . . . 0.1809 
'X-RAY DIFFRACTION' 2.53 2.90  . . 135 2711 99.09 . . . . 0.1760 . . . . . . . . . . . 0.2133 
'X-RAY DIFFRACTION' 2.90 3.65  . . 128 2745 99.03 . . . . 0.1417 . . . . . . . . . . . 0.1694 
'X-RAY DIFFRACTION' 3.65 32.96 . . 157 2823 98.74 . . . . 0.1173 . . . . . . . . . . . 0.1295 
# 
_struct.entry_id                     9CGG 
_struct.title                        
'Human DJ-1, 30 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CGG 
_struct_keywords.text            
'Glutathione-independent glyoxalase, mix-and-inject serial crystallography, Laue diffraction, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PARK7_HUMAN 
_struct_ref.pdbx_db_accession          Q99497 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQ
NLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGT
SFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9CGG 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 4 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 192 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q99497 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  189 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       189 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CGG GLY A 1 ? UNP Q99497 ? ? 'expression tag' -2 1 
1 9CGG SER A 2 ? UNP Q99497 ? ? 'expression tag' -1 2 
1 9CGG HIS A 3 ? UNP Q99497 ? ? 'expression tag' 0  3 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 2810  ? 
1 MORE         -17   ? 
1 'SSA (A^2)'  15070 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z         1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000  
2 'crystal symmetry operation' 5_555 x-y,-y,-z+2/3 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 50.7600000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 18  ? ALA A 32  ? GLU A 15  ALA A 29  1 ? 15 
HELX_P HELX_P2  AA2 LEU A 61  ? LYS A 66  ? LEU A 58  LYS A 63  1 ? 6  
HELX_P HELX_P3  AA3 GLY A 78  ? SER A 88  ? GLY A 75  SER A 85  1 ? 11 
HELX_P HELX_P4  AA4 SER A 88  ? ARG A 101 ? SER A 85  ARG A 98  1 ? 14 
HELX_P HELX_P5  AA5 PRO A 112 ? HIS A 118 ? PRO A 109 HIS A 115 1 ? 7  
HELX_P HELX_P6  AA6 HIS A 129 ? LEU A 131 ? HIS A 126 LEU A 128 5 ? 3  
HELX_P HELX_P7  AA7 ALA A 132 ? MET A 137 ? ALA A 129 MET A 134 1 ? 6  
HELX_P HELX_P8  AA8 GLY A 160 ? GLY A 162 ? GLY A 157 GLY A 159 5 ? 3  
HELX_P HELX_P9  AA9 THR A 163 ? GLY A 177 ? THR A 160 GLY A 174 1 ? 15 
HELX_P HELX_P10 AB1 GLY A 177 ? ALA A 186 ? GLY A 174 ALA A 183 1 ? 10 
HELX_P HELX_P11 AB2 PRO A 187 ? VAL A 189 ? PRO A 184 VAL A 186 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A ILE   108 C ? ? ? 1_555 A A1A7V 109 N ? ? A ILE   105 A A1A7V 106 1_555 ? ? ? ? ? ? ? 1.335 ? ? 
covale2 covale both ? A A1A7V 109 C ? ? ? 1_555 A ALA   110 N ? ? A A1A7V 106 A ALA   107 1_555 ? ? ? ? ? ? ? 1.333 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      A1A7V 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       109 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     . 
_pdbx_modification_feature.modified_residue_label_asym_id     . 
_pdbx_modification_feature.modified_residue_label_seq_id      . 
_pdbx_modification_feature.modified_residue_label_alt_id      . 
_pdbx_modification_feature.auth_comp_id                       A1A7V 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        106 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      . 
_pdbx_modification_feature.modified_residue_auth_asym_id      . 
_pdbx_modification_feature.modified_residue_auth_seq_id       . 
_pdbx_modification_feature.modified_residue_PDB_ins_code      . 
_pdbx_modification_feature.modified_residue_symmetry          . 
_pdbx_modification_feature.comp_id_linking_atom               . 
_pdbx_modification_feature.modified_residue_id_linking_atom   . 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        A1A7V 
_pdbx_modification_feature.type                               Lactoylation 
_pdbx_modification_feature.category                           'Named protein modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLY 
_struct_mon_prot_cis.label_seq_id           68 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLY 
_struct_mon_prot_cis.auth_seq_id            65 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    69 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     66 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -1.50 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 59  ? SER A 60  ? ALA A 56  SER A 57  
AA1 2 LYS A 35  ? GLY A 40  ? LYS A 32  GLY A 37  
AA1 3 ARG A 8   ? LEU A 13  ? ARG A 5   LEU A 10  
AA1 4 VAL A 72  ? LEU A 75  ? VAL A 69  LEU A 72  
AA1 5 LEU A 104 ? ILE A 108 ? LEU A 101 ILE A 105 
AA1 6 ILE A 155 ? SER A 158 ? ILE A 152 SER A 155 
AA1 7 VAL A 149 ? ASP A 152 ? VAL A 146 ASP A 149 
AA2 1 VAL A 47  ? GLN A 48  ? VAL A 44  GLN A 45  
AA2 2 VAL A 54  ? ILE A 55  ? VAL A 51  ILE A 52  
AA3 1 LYS A 125 ? VAL A 126 ? LYS A 122 VAL A 123 
AA3 2 THR A 143 ? TYR A 144 ? THR A 140 TYR A 141 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 59  ? O ALA A 56  N GLY A 40  ? N GLY A 37  
AA1 2 3 O ALA A 39  ? O ALA A 36  N VAL A 11  ? N VAL A 8   
AA1 3 4 N LEU A 10  ? N LEU A 7   O VAL A 74  ? O VAL A 71  
AA1 4 5 N LEU A 75  ? N LEU A 72  O ALA A 106 ? O ALA A 103 
AA1 5 6 N ILE A 105 ? N ILE A 102 O LEU A 156 ? O LEU A 153 
AA1 6 7 O THR A 157 ? O THR A 154 N GLU A 150 ? N GLU A 147 
AA2 1 2 N VAL A 47  ? N VAL A 44  O ILE A 55  ? O ILE A 52  
AA3 1 2 N VAL A 126 ? N VAL A 123 O THR A 143 ? O THR A 140 
# 
_pdbx_entry_details.entry_id                   9CGG 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    A1A7V 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     106 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             71.96 
_pdbx_validate_torsion.psi             -109.43 
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    A 
_pdbx_struct_mod_residue.label_comp_id    A1A7V 
_pdbx_struct_mod_residue.label_seq_id     109 
_pdbx_struct_mod_residue.auth_asym_id     A 
_pdbx_struct_mod_residue.auth_comp_id     A1A7V 
_pdbx_struct_mod_residue.auth_seq_id      106 
_pdbx_struct_mod_residue.PDB_ins_code     ? 
_pdbx_struct_mod_residue.parent_comp_id   CYS 
_pdbx_struct_mod_residue.details          'modified residue' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+1/3   
3 -x+y,-x,z+2/3  
4 x-y,-y,-z+2/3  
5 -x,-x+y,-z+1/3 
6 y,x,-z         
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       413 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.87 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY -2 ? A GLY 1 
2 1 Y 1 A SER -1 ? A SER 2 
3 1 Y 1 A HIS 0  ? A HIS 3 
4 1 Y 1 A MET 1  ? A MET 4 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1A7V C    C N N 1   
A1A7V N    N N N 2   
A1A7V O    O N N 3   
A1A7V CA   C N R 4   
A1A7V CB   C N N 5   
A1A7V SG   S N N 6   
A1A7V C1   C N N 7   
A1A7V O1   O N N 8   
A1A7V C2   C N S 9   
A1A7V O2   O N N 10  
A1A7V C3   C N N 11  
A1A7V H    H N N 12  
A1A7V H2   H N N 13  
A1A7V HA   H N N 14  
A1A7V HB3  H N N 15  
A1A7V HB2  H N N 16  
A1A7V H20  H N N 17  
A1A7V HO2  H N N 18  
A1A7V H3B  H N N 19  
A1A7V H3A  H N N 20  
A1A7V H3   H N N 21  
A1A7V OXT  O N N 22  
A1A7V HXT  H N N 23  
ALA   N    N N N 24  
ALA   CA   C N S 25  
ALA   C    C N N 26  
ALA   O    O N N 27  
ALA   CB   C N N 28  
ALA   OXT  O N N 29  
ALA   H    H N N 30  
ALA   H2   H N N 31  
ALA   HA   H N N 32  
ALA   HB1  H N N 33  
ALA   HB2  H N N 34  
ALA   HB3  H N N 35  
ALA   HXT  H N N 36  
ARG   N    N N N 37  
ARG   CA   C N S 38  
ARG   C    C N N 39  
ARG   O    O N N 40  
ARG   CB   C N N 41  
ARG   CG   C N N 42  
ARG   CD   C N N 43  
ARG   NE   N N N 44  
ARG   CZ   C N N 45  
ARG   NH1  N N N 46  
ARG   NH2  N N N 47  
ARG   OXT  O N N 48  
ARG   H    H N N 49  
ARG   H2   H N N 50  
ARG   HA   H N N 51  
ARG   HB2  H N N 52  
ARG   HB3  H N N 53  
ARG   HG2  H N N 54  
ARG   HG3  H N N 55  
ARG   HD2  H N N 56  
ARG   HD3  H N N 57  
ARG   HE   H N N 58  
ARG   HH11 H N N 59  
ARG   HH12 H N N 60  
ARG   HH21 H N N 61  
ARG   HH22 H N N 62  
ARG   HXT  H N N 63  
ASN   N    N N N 64  
ASN   CA   C N S 65  
ASN   C    C N N 66  
ASN   O    O N N 67  
ASN   CB   C N N 68  
ASN   CG   C N N 69  
ASN   OD1  O N N 70  
ASN   ND2  N N N 71  
ASN   OXT  O N N 72  
ASN   H    H N N 73  
ASN   H2   H N N 74  
ASN   HA   H N N 75  
ASN   HB2  H N N 76  
ASN   HB3  H N N 77  
ASN   HD21 H N N 78  
ASN   HD22 H N N 79  
ASN   HXT  H N N 80  
ASP   N    N N N 81  
ASP   CA   C N S 82  
ASP   C    C N N 83  
ASP   O    O N N 84  
ASP   CB   C N N 85  
ASP   CG   C N N 86  
ASP   OD1  O N N 87  
ASP   OD2  O N N 88  
ASP   OXT  O N N 89  
ASP   H    H N N 90  
ASP   H2   H N N 91  
ASP   HA   H N N 92  
ASP   HB2  H N N 93  
ASP   HB3  H N N 94  
ASP   HD2  H N N 95  
ASP   HXT  H N N 96  
CYS   N    N N N 97  
CYS   CA   C N R 98  
CYS   C    C N N 99  
CYS   O    O N N 100 
CYS   CB   C N N 101 
CYS   SG   S N N 102 
CYS   OXT  O N N 103 
CYS   H    H N N 104 
CYS   H2   H N N 105 
CYS   HA   H N N 106 
CYS   HB2  H N N 107 
CYS   HB3  H N N 108 
CYS   HG   H N N 109 
CYS   HXT  H N N 110 
GLN   N    N N N 111 
GLN   CA   C N S 112 
GLN   C    C N N 113 
GLN   O    O N N 114 
GLN   CB   C N N 115 
GLN   CG   C N N 116 
GLN   CD   C N N 117 
GLN   OE1  O N N 118 
GLN   NE2  N N N 119 
GLN   OXT  O N N 120 
GLN   H    H N N 121 
GLN   H2   H N N 122 
GLN   HA   H N N 123 
GLN   HB2  H N N 124 
GLN   HB3  H N N 125 
GLN   HG2  H N N 126 
GLN   HG3  H N N 127 
GLN   HE21 H N N 128 
GLN   HE22 H N N 129 
GLN   HXT  H N N 130 
GLU   N    N N N 131 
GLU   CA   C N S 132 
GLU   C    C N N 133 
GLU   O    O N N 134 
GLU   CB   C N N 135 
GLU   CG   C N N 136 
GLU   CD   C N N 137 
GLU   OE1  O N N 138 
GLU   OE2  O N N 139 
GLU   OXT  O N N 140 
GLU   H    H N N 141 
GLU   H2   H N N 142 
GLU   HA   H N N 143 
GLU   HB2  H N N 144 
GLU   HB3  H N N 145 
GLU   HG2  H N N 146 
GLU   HG3  H N N 147 
GLU   HE2  H N N 148 
GLU   HXT  H N N 149 
GLY   N    N N N 150 
GLY   CA   C N N 151 
GLY   C    C N N 152 
GLY   O    O N N 153 
GLY   OXT  O N N 154 
GLY   H    H N N 155 
GLY   H2   H N N 156 
GLY   HA2  H N N 157 
GLY   HA3  H N N 158 
GLY   HXT  H N N 159 
HIS   N    N N N 160 
HIS   CA   C N S 161 
HIS   C    C N N 162 
HIS   O    O N N 163 
HIS   CB   C N N 164 
HIS   CG   C Y N 165 
HIS   ND1  N Y N 166 
HIS   CD2  C Y N 167 
HIS   CE1  C Y N 168 
HIS   NE2  N Y N 169 
HIS   OXT  O N N 170 
HIS   H    H N N 171 
HIS   H2   H N N 172 
HIS   HA   H N N 173 
HIS   HB2  H N N 174 
HIS   HB3  H N N 175 
HIS   HD1  H N N 176 
HIS   HD2  H N N 177 
HIS   HE1  H N N 178 
HIS   HE2  H N N 179 
HIS   HXT  H N N 180 
HOH   O    O N N 181 
HOH   H1   H N N 182 
HOH   H2   H N N 183 
ILE   N    N N N 184 
ILE   CA   C N S 185 
ILE   C    C N N 186 
ILE   O    O N N 187 
ILE   CB   C N S 188 
ILE   CG1  C N N 189 
ILE   CG2  C N N 190 
ILE   CD1  C N N 191 
ILE   OXT  O N N 192 
ILE   H    H N N 193 
ILE   H2   H N N 194 
ILE   HA   H N N 195 
ILE   HB   H N N 196 
ILE   HG12 H N N 197 
ILE   HG13 H N N 198 
ILE   HG21 H N N 199 
ILE   HG22 H N N 200 
ILE   HG23 H N N 201 
ILE   HD11 H N N 202 
ILE   HD12 H N N 203 
ILE   HD13 H N N 204 
ILE   HXT  H N N 205 
LEU   N    N N N 206 
LEU   CA   C N S 207 
LEU   C    C N N 208 
LEU   O    O N N 209 
LEU   CB   C N N 210 
LEU   CG   C N N 211 
LEU   CD1  C N N 212 
LEU   CD2  C N N 213 
LEU   OXT  O N N 214 
LEU   H    H N N 215 
LEU   H2   H N N 216 
LEU   HA   H N N 217 
LEU   HB2  H N N 218 
LEU   HB3  H N N 219 
LEU   HG   H N N 220 
LEU   HD11 H N N 221 
LEU   HD12 H N N 222 
LEU   HD13 H N N 223 
LEU   HD21 H N N 224 
LEU   HD22 H N N 225 
LEU   HD23 H N N 226 
LEU   HXT  H N N 227 
LYS   N    N N N 228 
LYS   CA   C N S 229 
LYS   C    C N N 230 
LYS   O    O N N 231 
LYS   CB   C N N 232 
LYS   CG   C N N 233 
LYS   CD   C N N 234 
LYS   CE   C N N 235 
LYS   NZ   N N N 236 
LYS   OXT  O N N 237 
LYS   H    H N N 238 
LYS   H2   H N N 239 
LYS   HA   H N N 240 
LYS   HB2  H N N 241 
LYS   HB3  H N N 242 
LYS   HG2  H N N 243 
LYS   HG3  H N N 244 
LYS   HD2  H N N 245 
LYS   HD3  H N N 246 
LYS   HE2  H N N 247 
LYS   HE3  H N N 248 
LYS   HZ1  H N N 249 
LYS   HZ2  H N N 250 
LYS   HZ3  H N N 251 
LYS   HXT  H N N 252 
MET   N    N N N 253 
MET   CA   C N S 254 
MET   C    C N N 255 
MET   O    O N N 256 
MET   CB   C N N 257 
MET   CG   C N N 258 
MET   SD   S N N 259 
MET   CE   C N N 260 
MET   OXT  O N N 261 
MET   H    H N N 262 
MET   H2   H N N 263 
MET   HA   H N N 264 
MET   HB2  H N N 265 
MET   HB3  H N N 266 
MET   HG2  H N N 267 
MET   HG3  H N N 268 
MET   HE1  H N N 269 
MET   HE2  H N N 270 
MET   HE3  H N N 271 
MET   HXT  H N N 272 
PHE   N    N N N 273 
PHE   CA   C N S 274 
PHE   C    C N N 275 
PHE   O    O N N 276 
PHE   CB   C N N 277 
PHE   CG   C Y N 278 
PHE   CD1  C Y N 279 
PHE   CD2  C Y N 280 
PHE   CE1  C Y N 281 
PHE   CE2  C Y N 282 
PHE   CZ   C Y N 283 
PHE   OXT  O N N 284 
PHE   H    H N N 285 
PHE   H2   H N N 286 
PHE   HA   H N N 287 
PHE   HB2  H N N 288 
PHE   HB3  H N N 289 
PHE   HD1  H N N 290 
PHE   HD2  H N N 291 
PHE   HE1  H N N 292 
PHE   HE2  H N N 293 
PHE   HZ   H N N 294 
PHE   HXT  H N N 295 
PRO   N    N N N 296 
PRO   CA   C N S 297 
PRO   C    C N N 298 
PRO   O    O N N 299 
PRO   CB   C N N 300 
PRO   CG   C N N 301 
PRO   CD   C N N 302 
PRO   OXT  O N N 303 
PRO   H    H N N 304 
PRO   HA   H N N 305 
PRO   HB2  H N N 306 
PRO   HB3  H N N 307 
PRO   HG2  H N N 308 
PRO   HG3  H N N 309 
PRO   HD2  H N N 310 
PRO   HD3  H N N 311 
PRO   HXT  H N N 312 
SER   N    N N N 313 
SER   CA   C N S 314 
SER   C    C N N 315 
SER   O    O N N 316 
SER   CB   C N N 317 
SER   OG   O N N 318 
SER   OXT  O N N 319 
SER   H    H N N 320 
SER   H2   H N N 321 
SER   HA   H N N 322 
SER   HB2  H N N 323 
SER   HB3  H N N 324 
SER   HG   H N N 325 
SER   HXT  H N N 326 
THR   N    N N N 327 
THR   CA   C N S 328 
THR   C    C N N 329 
THR   O    O N N 330 
THR   CB   C N R 331 
THR   OG1  O N N 332 
THR   CG2  C N N 333 
THR   OXT  O N N 334 
THR   H    H N N 335 
THR   H2   H N N 336 
THR   HA   H N N 337 
THR   HB   H N N 338 
THR   HG1  H N N 339 
THR   HG21 H N N 340 
THR   HG22 H N N 341 
THR   HG23 H N N 342 
THR   HXT  H N N 343 
TYR   N    N N N 344 
TYR   CA   C N S 345 
TYR   C    C N N 346 
TYR   O    O N N 347 
TYR   CB   C N N 348 
TYR   CG   C Y N 349 
TYR   CD1  C Y N 350 
TYR   CD2  C Y N 351 
TYR   CE1  C Y N 352 
TYR   CE2  C Y N 353 
TYR   CZ   C Y N 354 
TYR   OH   O N N 355 
TYR   OXT  O N N 356 
TYR   H    H N N 357 
TYR   H2   H N N 358 
TYR   HA   H N N 359 
TYR   HB2  H N N 360 
TYR   HB3  H N N 361 
TYR   HD1  H N N 362 
TYR   HD2  H N N 363 
TYR   HE1  H N N 364 
TYR   HE2  H N N 365 
TYR   HH   H N N 366 
TYR   HXT  H N N 367 
VAL   N    N N N 368 
VAL   CA   C N S 369 
VAL   C    C N N 370 
VAL   O    O N N 371 
VAL   CB   C N N 372 
VAL   CG1  C N N 373 
VAL   CG2  C N N 374 
VAL   OXT  O N N 375 
VAL   H    H N N 376 
VAL   H2   H N N 377 
VAL   HA   H N N 378 
VAL   HB   H N N 379 
VAL   HG11 H N N 380 
VAL   HG12 H N N 381 
VAL   HG13 H N N 382 
VAL   HG21 H N N 383 
VAL   HG22 H N N 384 
VAL   HG23 H N N 385 
VAL   HXT  H N N 386 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1A7V N   CA   sing N N 1   
A1A7V O   C    doub N N 2   
A1A7V C   CA   sing N N 3   
A1A7V CA  CB   sing N N 4   
A1A7V CB  SG   sing N N 5   
A1A7V SG  C1   sing N N 6   
A1A7V O1  C1   doub N N 7   
A1A7V O2  C2   sing N N 8   
A1A7V C1  C2   sing N N 9   
A1A7V C2  C3   sing N N 10  
A1A7V N   H    sing N N 11  
A1A7V N   H2   sing N N 12  
A1A7V CA  HA   sing N N 13  
A1A7V CB  HB3  sing N N 14  
A1A7V CB  HB2  sing N N 15  
A1A7V C2  H20  sing N N 16  
A1A7V O2  HO2  sing N N 17  
A1A7V C3  H3B  sing N N 18  
A1A7V C3  H3A  sing N N 19  
A1A7V C3  H3   sing N N 20  
A1A7V C   OXT  sing N N 21  
A1A7V OXT HXT  sing N N 22  
ALA   N   CA   sing N N 23  
ALA   N   H    sing N N 24  
ALA   N   H2   sing N N 25  
ALA   CA  C    sing N N 26  
ALA   CA  CB   sing N N 27  
ALA   CA  HA   sing N N 28  
ALA   C   O    doub N N 29  
ALA   C   OXT  sing N N 30  
ALA   CB  HB1  sing N N 31  
ALA   CB  HB2  sing N N 32  
ALA   CB  HB3  sing N N 33  
ALA   OXT HXT  sing N N 34  
ARG   N   CA   sing N N 35  
ARG   N   H    sing N N 36  
ARG   N   H2   sing N N 37  
ARG   CA  C    sing N N 38  
ARG   CA  CB   sing N N 39  
ARG   CA  HA   sing N N 40  
ARG   C   O    doub N N 41  
ARG   C   OXT  sing N N 42  
ARG   CB  CG   sing N N 43  
ARG   CB  HB2  sing N N 44  
ARG   CB  HB3  sing N N 45  
ARG   CG  CD   sing N N 46  
ARG   CG  HG2  sing N N 47  
ARG   CG  HG3  sing N N 48  
ARG   CD  NE   sing N N 49  
ARG   CD  HD2  sing N N 50  
ARG   CD  HD3  sing N N 51  
ARG   NE  CZ   sing N N 52  
ARG   NE  HE   sing N N 53  
ARG   CZ  NH1  sing N N 54  
ARG   CZ  NH2  doub N N 55  
ARG   NH1 HH11 sing N N 56  
ARG   NH1 HH12 sing N N 57  
ARG   NH2 HH21 sing N N 58  
ARG   NH2 HH22 sing N N 59  
ARG   OXT HXT  sing N N 60  
ASN   N   CA   sing N N 61  
ASN   N   H    sing N N 62  
ASN   N   H2   sing N N 63  
ASN   CA  C    sing N N 64  
ASN   CA  CB   sing N N 65  
ASN   CA  HA   sing N N 66  
ASN   C   O    doub N N 67  
ASN   C   OXT  sing N N 68  
ASN   CB  CG   sing N N 69  
ASN   CB  HB2  sing N N 70  
ASN   CB  HB3  sing N N 71  
ASN   CG  OD1  doub N N 72  
ASN   CG  ND2  sing N N 73  
ASN   ND2 HD21 sing N N 74  
ASN   ND2 HD22 sing N N 75  
ASN   OXT HXT  sing N N 76  
ASP   N   CA   sing N N 77  
ASP   N   H    sing N N 78  
ASP   N   H2   sing N N 79  
ASP   CA  C    sing N N 80  
ASP   CA  CB   sing N N 81  
ASP   CA  HA   sing N N 82  
ASP   C   O    doub N N 83  
ASP   C   OXT  sing N N 84  
ASP   CB  CG   sing N N 85  
ASP   CB  HB2  sing N N 86  
ASP   CB  HB3  sing N N 87  
ASP   CG  OD1  doub N N 88  
ASP   CG  OD2  sing N N 89  
ASP   OD2 HD2  sing N N 90  
ASP   OXT HXT  sing N N 91  
CYS   N   CA   sing N N 92  
CYS   N   H    sing N N 93  
CYS   N   H2   sing N N 94  
CYS   CA  C    sing N N 95  
CYS   CA  CB   sing N N 96  
CYS   CA  HA   sing N N 97  
CYS   C   O    doub N N 98  
CYS   C   OXT  sing N N 99  
CYS   CB  SG   sing N N 100 
CYS   CB  HB2  sing N N 101 
CYS   CB  HB3  sing N N 102 
CYS   SG  HG   sing N N 103 
CYS   OXT HXT  sing N N 104 
GLN   N   CA   sing N N 105 
GLN   N   H    sing N N 106 
GLN   N   H2   sing N N 107 
GLN   CA  C    sing N N 108 
GLN   CA  CB   sing N N 109 
GLN   CA  HA   sing N N 110 
GLN   C   O    doub N N 111 
GLN   C   OXT  sing N N 112 
GLN   CB  CG   sing N N 113 
GLN   CB  HB2  sing N N 114 
GLN   CB  HB3  sing N N 115 
GLN   CG  CD   sing N N 116 
GLN   CG  HG2  sing N N 117 
GLN   CG  HG3  sing N N 118 
GLN   CD  OE1  doub N N 119 
GLN   CD  NE2  sing N N 120 
GLN   NE2 HE21 sing N N 121 
GLN   NE2 HE22 sing N N 122 
GLN   OXT HXT  sing N N 123 
GLU   N   CA   sing N N 124 
GLU   N   H    sing N N 125 
GLU   N   H2   sing N N 126 
GLU   CA  C    sing N N 127 
GLU   CA  CB   sing N N 128 
GLU   CA  HA   sing N N 129 
GLU   C   O    doub N N 130 
GLU   C   OXT  sing N N 131 
GLU   CB  CG   sing N N 132 
GLU   CB  HB2  sing N N 133 
GLU   CB  HB3  sing N N 134 
GLU   CG  CD   sing N N 135 
GLU   CG  HG2  sing N N 136 
GLU   CG  HG3  sing N N 137 
GLU   CD  OE1  doub N N 138 
GLU   CD  OE2  sing N N 139 
GLU   OE2 HE2  sing N N 140 
GLU   OXT HXT  sing N N 141 
GLY   N   CA   sing N N 142 
GLY   N   H    sing N N 143 
GLY   N   H2   sing N N 144 
GLY   CA  C    sing N N 145 
GLY   CA  HA2  sing N N 146 
GLY   CA  HA3  sing N N 147 
GLY   C   O    doub N N 148 
GLY   C   OXT  sing N N 149 
GLY   OXT HXT  sing N N 150 
HIS   N   CA   sing N N 151 
HIS   N   H    sing N N 152 
HIS   N   H2   sing N N 153 
HIS   CA  C    sing N N 154 
HIS   CA  CB   sing N N 155 
HIS   CA  HA   sing N N 156 
HIS   C   O    doub N N 157 
HIS   C   OXT  sing N N 158 
HIS   CB  CG   sing N N 159 
HIS   CB  HB2  sing N N 160 
HIS   CB  HB3  sing N N 161 
HIS   CG  ND1  sing Y N 162 
HIS   CG  CD2  doub Y N 163 
HIS   ND1 CE1  doub Y N 164 
HIS   ND1 HD1  sing N N 165 
HIS   CD2 NE2  sing Y N 166 
HIS   CD2 HD2  sing N N 167 
HIS   CE1 NE2  sing Y N 168 
HIS   CE1 HE1  sing N N 169 
HIS   NE2 HE2  sing N N 170 
HIS   OXT HXT  sing N N 171 
HOH   O   H1   sing N N 172 
HOH   O   H2   sing N N 173 
ILE   N   CA   sing N N 174 
ILE   N   H    sing N N 175 
ILE   N   H2   sing N N 176 
ILE   CA  C    sing N N 177 
ILE   CA  CB   sing N N 178 
ILE   CA  HA   sing N N 179 
ILE   C   O    doub N N 180 
ILE   C   OXT  sing N N 181 
ILE   CB  CG1  sing N N 182 
ILE   CB  CG2  sing N N 183 
ILE   CB  HB   sing N N 184 
ILE   CG1 CD1  sing N N 185 
ILE   CG1 HG12 sing N N 186 
ILE   CG1 HG13 sing N N 187 
ILE   CG2 HG21 sing N N 188 
ILE   CG2 HG22 sing N N 189 
ILE   CG2 HG23 sing N N 190 
ILE   CD1 HD11 sing N N 191 
ILE   CD1 HD12 sing N N 192 
ILE   CD1 HD13 sing N N 193 
ILE   OXT HXT  sing N N 194 
LEU   N   CA   sing N N 195 
LEU   N   H    sing N N 196 
LEU   N   H2   sing N N 197 
LEU   CA  C    sing N N 198 
LEU   CA  CB   sing N N 199 
LEU   CA  HA   sing N N 200 
LEU   C   O    doub N N 201 
LEU   C   OXT  sing N N 202 
LEU   CB  CG   sing N N 203 
LEU   CB  HB2  sing N N 204 
LEU   CB  HB3  sing N N 205 
LEU   CG  CD1  sing N N 206 
LEU   CG  CD2  sing N N 207 
LEU   CG  HG   sing N N 208 
LEU   CD1 HD11 sing N N 209 
LEU   CD1 HD12 sing N N 210 
LEU   CD1 HD13 sing N N 211 
LEU   CD2 HD21 sing N N 212 
LEU   CD2 HD22 sing N N 213 
LEU   CD2 HD23 sing N N 214 
LEU   OXT HXT  sing N N 215 
LYS   N   CA   sing N N 216 
LYS   N   H    sing N N 217 
LYS   N   H2   sing N N 218 
LYS   CA  C    sing N N 219 
LYS   CA  CB   sing N N 220 
LYS   CA  HA   sing N N 221 
LYS   C   O    doub N N 222 
LYS   C   OXT  sing N N 223 
LYS   CB  CG   sing N N 224 
LYS   CB  HB2  sing N N 225 
LYS   CB  HB3  sing N N 226 
LYS   CG  CD   sing N N 227 
LYS   CG  HG2  sing N N 228 
LYS   CG  HG3  sing N N 229 
LYS   CD  CE   sing N N 230 
LYS   CD  HD2  sing N N 231 
LYS   CD  HD3  sing N N 232 
LYS   CE  NZ   sing N N 233 
LYS   CE  HE2  sing N N 234 
LYS   CE  HE3  sing N N 235 
LYS   NZ  HZ1  sing N N 236 
LYS   NZ  HZ2  sing N N 237 
LYS   NZ  HZ3  sing N N 238 
LYS   OXT HXT  sing N N 239 
MET   N   CA   sing N N 240 
MET   N   H    sing N N 241 
MET   N   H2   sing N N 242 
MET   CA  C    sing N N 243 
MET   CA  CB   sing N N 244 
MET   CA  HA   sing N N 245 
MET   C   O    doub N N 246 
MET   C   OXT  sing N N 247 
MET   CB  CG   sing N N 248 
MET   CB  HB2  sing N N 249 
MET   CB  HB3  sing N N 250 
MET   CG  SD   sing N N 251 
MET   CG  HG2  sing N N 252 
MET   CG  HG3  sing N N 253 
MET   SD  CE   sing N N 254 
MET   CE  HE1  sing N N 255 
MET   CE  HE2  sing N N 256 
MET   CE  HE3  sing N N 257 
MET   OXT HXT  sing N N 258 
PHE   N   CA   sing N N 259 
PHE   N   H    sing N N 260 
PHE   N   H2   sing N N 261 
PHE   CA  C    sing N N 262 
PHE   CA  CB   sing N N 263 
PHE   CA  HA   sing N N 264 
PHE   C   O    doub N N 265 
PHE   C   OXT  sing N N 266 
PHE   CB  CG   sing N N 267 
PHE   CB  HB2  sing N N 268 
PHE   CB  HB3  sing N N 269 
PHE   CG  CD1  doub Y N 270 
PHE   CG  CD2  sing Y N 271 
PHE   CD1 CE1  sing Y N 272 
PHE   CD1 HD1  sing N N 273 
PHE   CD2 CE2  doub Y N 274 
PHE   CD2 HD2  sing N N 275 
PHE   CE1 CZ   doub Y N 276 
PHE   CE1 HE1  sing N N 277 
PHE   CE2 CZ   sing Y N 278 
PHE   CE2 HE2  sing N N 279 
PHE   CZ  HZ   sing N N 280 
PHE   OXT HXT  sing N N 281 
PRO   N   CA   sing N N 282 
PRO   N   CD   sing N N 283 
PRO   N   H    sing N N 284 
PRO   CA  C    sing N N 285 
PRO   CA  CB   sing N N 286 
PRO   CA  HA   sing N N 287 
PRO   C   O    doub N N 288 
PRO   C   OXT  sing N N 289 
PRO   CB  CG   sing N N 290 
PRO   CB  HB2  sing N N 291 
PRO   CB  HB3  sing N N 292 
PRO   CG  CD   sing N N 293 
PRO   CG  HG2  sing N N 294 
PRO   CG  HG3  sing N N 295 
PRO   CD  HD2  sing N N 296 
PRO   CD  HD3  sing N N 297 
PRO   OXT HXT  sing N N 298 
SER   N   CA   sing N N 299 
SER   N   H    sing N N 300 
SER   N   H2   sing N N 301 
SER   CA  C    sing N N 302 
SER   CA  CB   sing N N 303 
SER   CA  HA   sing N N 304 
SER   C   O    doub N N 305 
SER   C   OXT  sing N N 306 
SER   CB  OG   sing N N 307 
SER   CB  HB2  sing N N 308 
SER   CB  HB3  sing N N 309 
SER   OG  HG   sing N N 310 
SER   OXT HXT  sing N N 311 
THR   N   CA   sing N N 312 
THR   N   H    sing N N 313 
THR   N   H2   sing N N 314 
THR   CA  C    sing N N 315 
THR   CA  CB   sing N N 316 
THR   CA  HA   sing N N 317 
THR   C   O    doub N N 318 
THR   C   OXT  sing N N 319 
THR   CB  OG1  sing N N 320 
THR   CB  CG2  sing N N 321 
THR   CB  HB   sing N N 322 
THR   OG1 HG1  sing N N 323 
THR   CG2 HG21 sing N N 324 
THR   CG2 HG22 sing N N 325 
THR   CG2 HG23 sing N N 326 
THR   OXT HXT  sing N N 327 
TYR   N   CA   sing N N 328 
TYR   N   H    sing N N 329 
TYR   N   H2   sing N N 330 
TYR   CA  C    sing N N 331 
TYR   CA  CB   sing N N 332 
TYR   CA  HA   sing N N 333 
TYR   C   O    doub N N 334 
TYR   C   OXT  sing N N 335 
TYR   CB  CG   sing N N 336 
TYR   CB  HB2  sing N N 337 
TYR   CB  HB3  sing N N 338 
TYR   CG  CD1  doub Y N 339 
TYR   CG  CD2  sing Y N 340 
TYR   CD1 CE1  sing Y N 341 
TYR   CD1 HD1  sing N N 342 
TYR   CD2 CE2  doub Y N 343 
TYR   CD2 HD2  sing N N 344 
TYR   CE1 CZ   doub Y N 345 
TYR   CE1 HE1  sing N N 346 
TYR   CE2 CZ   sing Y N 347 
TYR   CE2 HE2  sing N N 348 
TYR   CZ  OH   sing N N 349 
TYR   OH  HH   sing N N 350 
TYR   OXT HXT  sing N N 351 
VAL   N   CA   sing N N 352 
VAL   N   H    sing N N 353 
VAL   N   H2   sing N N 354 
VAL   CA  C    sing N N 355 
VAL   CA  CB   sing N N 356 
VAL   CA  HA   sing N N 357 
VAL   C   O    doub N N 358 
VAL   C   OXT  sing N N 359 
VAL   CB  CG1  sing N N 360 
VAL   CB  CG2  sing N N 361 
VAL   CB  HB   sing N N 362 
VAL   CG1 HG11 sing N N 363 
VAL   CG1 HG12 sing N N 364 
VAL   CG1 HG13 sing N N 365 
VAL   CG2 HG21 sing N N 366 
VAL   CG2 HG22 sing N N 367 
VAL   CG2 HG23 sing N N 368 
VAL   OXT HXT  sing N N 369 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R35GM153337 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          'Unpublished DJ-1 structure from X-ray source' 
# 
_pdbx_serial_crystallography_data_reduction.diffrn_id             1 
_pdbx_serial_crystallography_data_reduction.frames_total          20000 
_pdbx_serial_crystallography_data_reduction.xfel_pulse_events     ? 
_pdbx_serial_crystallography_data_reduction.frame_hits            ? 
_pdbx_serial_crystallography_data_reduction.crystal_hits          1051 
_pdbx_serial_crystallography_data_reduction.droplet_hits          ? 
_pdbx_serial_crystallography_data_reduction.frames_failed_index   ? 
_pdbx_serial_crystallography_data_reduction.frames_indexed        1007 
_pdbx_serial_crystallography_data_reduction.lattices_indexed      ? 
_pdbx_serial_crystallography_data_reduction.xfel_run_numbers      ? 
_pdbx_serial_crystallography_data_reduction.lattices_merged       ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   'concentric flow microfluidic mixer' 
_pdbx_serial_crystallography_sample_delivery.method        injection 
# 
_space_group.name_H-M_alt     'P 31 2 1' 
_space_group.name_Hall        
;P 31 2"
;
_space_group.IT_number        152 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9CGG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013153 
_atom_sites.fract_transf_matrix[1][2]   0.007594 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015187 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013134 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . ALA   A 1 5   ? 31.50981 9.02876   -0.93608 1.000 84.71855  ? 2   ALA   A N    1 
ATOM   2    C CA   . ALA   A 1 5   ? 32.95033 8.86176   -0.78527 1.000 109.22041 ? 2   ALA   A CA   1 
ATOM   3    C C    . ALA   A 1 5   ? 33.31002 8.49264   0.65276  1.000 102.83027 ? 2   ALA   A C    1 
ATOM   4    O O    . ALA   A 1 5   ? 34.44684 8.68433   1.08631  1.000 93.84140  ? 2   ALA   A O    1 
ATOM   5    C CB   . ALA   A 1 5   ? 33.67553 10.13436  -1.20218 1.000 85.87417  ? 2   ALA   A CB   1 
ATOM   6    H HA   . ALA   A 1 5   ? 33.24649 8.14167   -1.36376 1.000 130.99887 ? 2   ALA   A HA   1 
ATOM   7    H HB1  . ALA   A 1 5   ? 34.63174 9.99514   -1.11743 1.000 102.98338 ? 2   ALA   A HB1  1 
ATOM   8    H HB2  . ALA   A 1 5   ? 33.45133 10.33816  -2.12365 1.000 102.98338 ? 2   ALA   A HB2  1 
ATOM   9    H HB3  . ALA   A 1 5   ? 33.39468 10.86147  -0.62484 1.000 102.98338 ? 2   ALA   A HB3  1 
ATOM   10   N N    . SER   A 1 6   ? 32.33843 7.95883   1.38730  1.000 72.46110  ? 3   SER   A N    1 
ATOM   11   C CA   . SER   A 1 6   ? 32.50771 7.61067   2.79157  1.000 73.72163  ? 3   SER   A CA   1 
ATOM   12   C C    . SER   A 1 6   ? 32.58510 6.09724   2.93709  1.000 42.19293  ? 3   SER   A C    1 
ATOM   13   O O    . SER   A 1 6   ? 31.73708 5.37431   2.40376  1.000 50.64727  ? 3   SER   A O    1 
ATOM   14   C CB   . SER   A 1 6   ? 31.35327 8.16425   3.63030  1.000 89.70856  ? 3   SER   A CB   1 
ATOM   15   O OG   . SER   A 1 6   ? 31.64013 8.08061   5.01480  1.000 70.01763  ? 3   SER   A OG   1 
ATOM   16   H H    . SER   A 1 6   ? 31.55235 7.78517   1.08476  1.000 86.88769  ? 3   SER   A H    1 
ATOM   17   H HA   . SER   A 1 6   ? 33.33784 7.98889   3.12130  1.000 88.40033  ? 3   SER   A HA   1 
ATOM   18   H HB2  . SER   A 1 6   ? 31.21107 9.09431   3.39436  1.000 107.58465 ? 3   SER   A HB2  1 
ATOM   19   H HB3  . SER   A 1 6   ? 30.55332 7.64850   3.44329  1.000 107.58465 ? 3   SER   A HB3  1 
ATOM   20   H HG   . SER   A 1 6   ? 30.99943 8.39157   5.46024  1.000 83.95552  ? 3   SER   A HG   1 
ATOM   21   N N    . LYS   A 1 7   ? 33.59744 5.62494   3.66037  1.000 44.43896  ? 4   LYS   A N    1 
ATOM   22   C CA   . LYS   A 1 7   ? 33.74572 4.19720   3.90602  1.000 32.92066  ? 4   LYS   A CA   1 
ATOM   23   C C    . LYS   A 1 7   ? 32.71798 3.72806   4.93029  1.000 32.21911  ? 4   LYS   A C    1 
ATOM   24   O O    . LYS   A 1 7   ? 32.28630 4.48661   5.80264  1.000 30.86268  ? 4   LYS   A O    1 
ATOM   25   C CB   . LYS   A 1 7   ? 35.15620 3.88240   4.40378  1.000 35.04944  ? 4   LYS   A CB   1 
ATOM   26   C CG   . LYS   A 1 7   ? 36.27570 4.42910   3.52819  1.000 41.71927  ? 4   LYS   A CG   1 
ATOM   27   C CD   . LYS   A 1 7   ? 36.59398 3.51260   2.35915  1.000 42.69831  ? 4   LYS   A CD   1 
ATOM   28   C CE   . LYS   A 1 7   ? 37.75388 4.06451   1.54118  1.000 53.75588  ? 4   LYS   A CE   1 
ATOM   29   N NZ   . LYS   A 1 7   ? 38.21961 3.11689   0.49187  1.000 68.98276  ? 4   LYS   A NZ   1 
ATOM   30   H H    . LYS   A 1 7   ? 34.21004 6.11066   4.01870  1.000 53.26112  ? 4   LYS   A H    1 
ATOM   31   H HA   . LYS   A 1 7   ? 33.60408 3.70935   3.07967  1.000 39.43917  ? 4   LYS   A HA   1 
ATOM   32   H HB2  . LYS   A 1 7   ? 35.26355 4.26538   5.28848  1.000 41.99371  ? 4   LYS   A HB2  1 
ATOM   33   H HB3  . LYS   A 1 7   ? 35.26091 2.91892   4.44441  1.000 41.99371  ? 4   LYS   A HB3  1 
ATOM   34   H HG2  . LYS   A 1 7   ? 36.00875 5.29077   3.17159  1.000 49.99749  ? 4   LYS   A HG2  1 
ATOM   35   H HG3  . LYS   A 1 7   ? 37.07931 4.52582   4.06276  1.000 49.99749  ? 4   LYS   A HG3  1 
ATOM   36   H HD2  . LYS   A 1 7   ? 36.84178 2.63605   2.69255  1.000 51.17235  ? 4   LYS   A HD2  1 
ATOM   37   H HD3  . LYS   A 1 7   ? 35.81718 3.44085   1.78266  1.000 51.17235  ? 4   LYS   A HD3  1 
ATOM   38   H HE2  . LYS   A 1 7   ? 37.47103 4.88217   1.10264  1.000 64.44143  ? 4   LYS   A HE2  1 
ATOM   39   H HE3  . LYS   A 1 7   ? 38.50025 4.24671   2.13333  1.000 64.44143  ? 4   LYS   A HE3  1 
ATOM   40   H HZ1  . LYS   A 1 7   ? 38.87317 3.48788   0.01508  1.000 82.71368  ? 4   LYS   A HZ1  1 
ATOM   41   H HZ2  . LYS   A 1 7   ? 38.52500 2.37095   0.86924  1.000 82.71368  ? 4   LYS   A HZ2  1 
ATOM   42   H HZ3  . LYS   A 1 7   ? 37.54636 2.91052   -0.05241 1.000 82.71368  ? 4   LYS   A HZ3  1 
ATOM   43   N N    . ARG   A 1 8   ? 32.33036 2.45928   4.81962  1.000 27.24800  ? 5   ARG   A N    1 
ATOM   44   C CA   . ARG   A 1 8   ? 31.29242 1.87157   5.65540  1.000 33.75307  ? 5   ARG   A CA   1 
ATOM   45   C C    . ARG   A 1 8   ? 31.83365 0.63230   6.35522  1.000 33.86392  ? 5   ARG   A C    1 
ATOM   46   O O    . ARG   A 1 8   ? 32.53333 -0.18318  5.74503  1.000 25.91636  ? 5   ARG   A O    1 
ATOM   47   C CB   . ARG   A 1 8   ? 30.05588 1.50339   4.82164  1.000 37.55230  ? 5   ARG   A CB   1 
ATOM   48   C CG   . ARG   A 1 8   ? 29.77877 2.46505   3.67388  1.000 58.12396  ? 5   ARG   A CG   1 
ATOM   49   C CD   . ARG   A 1 8   ? 28.46034 2.16747   2.96697  1.000 58.40981  ? 5   ARG   A CD   1 
ATOM   50   N NE   . ARG   A 1 8   ? 27.34013 2.85462   3.60098  1.000 81.84051  ? 5   ARG   A NE   1 
ATOM   51   C CZ   . ARG   A 1 8   ? 26.42352 2.27846   4.36970  1.000 100.05417 ? 5   ARG   A CZ   1 
ATOM   52   N NH1  . ARG   A 1 8   ? 26.42713 0.97509   4.60004  1.000 77.33922  ? 5   ARG   A NH1  1 
ATOM   53   N NH2  . ARG   A 1 8   ? 25.47467 3.03117   4.91923  1.000 97.99837  ? 5   ARG   A NH2  1 
ATOM   54   H H    . ARG   A 1 8   ? 32.66442 1.90657   4.25171  1.000 32.63197  ? 5   ARG   A H    1 
ATOM   55   H HA   . ARG   A 1 8   ? 31.02400 2.50939   6.33514  1.000 40.43806  ? 5   ARG   A HA   1 
ATOM   56   H HB2  . ARG   A 1 8   ? 30.18757 0.62036   4.44242  1.000 44.99714  ? 5   ARG   A HB2  1 
ATOM   57   H HB3  . ARG   A 1 8   ? 29.27820 1.50287   5.40139  1.000 44.99714  ? 5   ARG   A HB3  1 
ATOM   58   H HG2  . ARG   A 1 8   ? 29.73592 3.36972   4.02121  1.000 69.68313  ? 5   ARG   A HG2  1 
ATOM   59   H HG3  . ARG   A 1 8   ? 30.49252 2.39385   3.02089  1.000 69.68313  ? 5   ARG   A HG3  1 
ATOM   60   H HD2  . ARG   A 1 8   ? 28.51701 2.46456   2.04533  1.000 70.02614  ? 5   ARG   A HD2  1 
ATOM   61   H HD3  . ARG   A 1 8   ? 28.28865 1.21329   2.99800  1.000 70.02614  ? 5   ARG   A HD3  1 
ATOM   62   H HE   . ARG   A 1 8   ? 27.26773 3.70085   3.46590  1.000 98.14299  ? 5   ARG   A HE   1 
ATOM   63   H HH11 . ARG   A 1 8   ? 25.82245 0.62541   5.10172  1.000 92.74144  ? 5   ARG   A HH11 1 
ATOM   64   H HH12 . ARG   A 1 8   ? 27.03415 0.47789   4.24802  1.000 92.74144  ? 5   ARG   A HH12 1 
ATOM   65   H HH21 . ARG   A 1 8   ? 24.87515 2.67025   5.41913  1.000 117.53242 ? 5   ARG   A HH21 1 
ATOM   66   H HH22 . ARG   A 1 8   ? 25.46066 3.87882   4.77467  1.000 117.53242 ? 5   ARG   A HH22 1 
ATOM   67   N N    . ALA   A 1 9   ? 31.50458 0.49622   7.63829  1.000 28.48927  ? 6   ALA   A N    1 
ATOM   68   C CA   . ALA   A 1 9   ? 31.93623 -0.63272  8.44923  1.000 23.84499  ? 6   ALA   A CA   1 
ATOM   69   C C    . ALA   A 1 9   ? 30.72545 -1.30022  9.08213  1.000 22.19287  ? 6   ALA   A C    1 
ATOM   70   O O    . ALA   A 1 9   ? 29.81060 -0.62190  9.55886  1.000 28.76189  ? 6   ALA   A O    1 
ATOM   71   C CB   . ALA   A 1 9   ? 32.91472 -0.19277  9.54807  1.000 25.26371  ? 6   ALA   A CB   1 
ATOM   72   H H    . ALA   A 1 9   ? 31.01976 1.06076   8.06938  1.000 34.12150  ? 6   ALA   A H    1 
ATOM   73   H HA   . ALA   A 1 9   ? 32.38286 -1.28122  7.88279  1.000 28.54836  ? 6   ALA   A HA   1 
ATOM   74   H HB1  . ALA   A 1 9   ? 33.19250 -0.97226  10.05416 1.000 30.25082  ? 6   ALA   A HB1  1 
ATOM   75   H HB2  . ALA   A 1 9   ? 33.68622 0.22556   9.13494  1.000 30.25082  ? 6   ALA   A HB2  1 
ATOM   76   H HB3  . ALA   A 1 9   ? 32.46907 0.43981   10.13300 1.000 30.25082  ? 6   ALA   A HB3  1 
ATOM   77   N N    . LEU   A 1 10  ? 30.72658 -2.63083  9.08493  1.000 25.72715  ? 7   LEU   A N    1 
ATOM   78   C CA   . LEU   A 1 10  ? 29.68655 -3.42517  9.72622  1.000 19.86351  ? 7   LEU   A CA   1 
ATOM   79   C C    . LEU   A 1 10  ? 30.28830 -4.13557  10.93020 1.000 23.91401  ? 7   LEU   A C    1 
ATOM   80   O O    . LEU   A 1 10  ? 31.24292 -4.90746  10.78658 1.000 22.05949  ? 7   LEU   A O    1 
ATOM   81   C CB   . LEU   A 1 10  ? 29.08397 -4.44300  8.75826  1.000 24.57771  ? 7   LEU   A CB   1 
ATOM   82   C CG   . LEU   A 1 10  ? 28.02678 -5.36434  9.37514  1.000 30.07744  ? 7   LEU   A CG   1 
ATOM   83   C CD1  . LEU   A 1 10  ? 26.77935 -4.57259  9.74690  1.000 32.83691  ? 7   LEU   A CD1  1 
ATOM   84   C CD2  . LEU   A 1 10  ? 27.68527 -6.50944  8.43606  1.000 33.02980  ? 7   LEU   A CD2  1 
ATOM   85   H H    . LEU   A 1 10  ? 31.33707 -3.10733  8.71097  1.000 30.80695  ? 7   LEU   A H    1 
ATOM   86   H HA   . LEU   A 1 10  ? 28.97743 -2.83644  10.02862 1.000 23.77058  ? 7   LEU   A HA   1 
ATOM   87   H HB2  . LEU   A 1 10  ? 28.66328 -3.96187  8.02858  1.000 29.42763  ? 7   LEU   A HB2  1 
ATOM   88   H HB3  . LEU   A 1 10  ? 29.79835 -5.00383  8.41762  1.000 29.42763  ? 7   LEU   A HB3  1 
ATOM   89   H HG   . LEU   A 1 10  ? 28.38719 -5.75322  10.18741 1.000 36.02731  ? 7   LEU   A HG   1 
ATOM   90   H HD11 . LEU   A 1 10  ? 26.09001 -5.18874  10.04030 1.000 39.33866  ? 7   LEU   A HD11 1 
ATOM   91   H HD12 . LEU   A 1 10  ? 26.99841 -3.95597  10.46292 1.000 39.33866  ? 7   LEU   A HD12 1 
ATOM   92   H HD13 . LEU   A 1 10  ? 26.47391 -4.08072  8.96865  1.000 39.33866  ? 7   LEU   A HD13 1 
ATOM   93   H HD21 . LEU   A 1 10  ? 26.99397 -7.05542  8.84213  1.000 39.57013  ? 7   LEU   A HD21 1 
ATOM   94   H HD22 . LEU   A 1 10  ? 27.36733 -6.14440  7.59548  1.000 39.57013  ? 7   LEU   A HD22 1 
ATOM   95   H HD23 . LEU   A 1 10  ? 28.48162 -7.04231  8.28515  1.000 39.57013  ? 7   LEU   A HD23 1 
ATOM   96   N N    . VAL   A 1 11  ? 29.72729 -3.87715  12.10706 1.000 25.77097  ? 8   VAL   A N    1 
ATOM   97   C CA   . VAL   A 1 11  ? 30.12191 -4.53898  13.34516 1.000 18.17111  ? 8   VAL   A CA   1 
ATOM   98   C C    . VAL   A 1 11  ? 28.95760 -5.41770  13.77990 1.000 24.21055  ? 8   VAL   A C    1 
ATOM   99   O O    . VAL   A 1 11  ? 27.85366 -4.91817  14.02917 1.000 25.25175  ? 8   VAL   A O    1 
ATOM   100  C CB   . VAL   A 1 11  ? 30.49647 -3.52325  14.43519 1.000 18.64007  ? 8   VAL   A CB   1 
ATOM   101  C CG1  . VAL   A 1 11  ? 30.87754 -4.23443  15.72393 1.000 20.40810  ? 8   VAL   A CG1  1 
ATOM   102  C CG2  . VAL   A 1 11  ? 31.63593 -2.63067  13.95960 1.000 18.38785  ? 8   VAL   A CG2  1 
ATOM   103  H H    . VAL   A 1 11  ? 29.09572 -3.30376  12.21632 1.000 30.85953  ? 8   VAL   A H    1 
ATOM   104  H HA   . VAL   A 1 11  ? 30.89361 -5.10465  13.18578 1.000 21.73971  ? 8   VAL   A HA   1 
ATOM   105  H HB   . VAL   A 1 11  ? 29.72604 -2.96305  14.61826 1.000 22.30245  ? 8   VAL   A HB   1 
ATOM   106  H HG11 . VAL   A 1 11  ? 31.25092 -3.58771  16.34300 1.000 24.42409  ? 8   VAL   A HG11 1 
ATOM   107  H HG12 . VAL   A 1 11  ? 30.08410 -4.63966  16.10752 1.000 24.42409  ? 8   VAL   A HG12 1 
ATOM   108  H HG13 . VAL   A 1 11  ? 31.53506 -4.91906  15.52428 1.000 24.42409  ? 8   VAL   A HG13 1 
ATOM   109  H HG21 . VAL   A 1 11  ? 31.81314 -1.95777  14.63539 1.000 21.99980  ? 8   VAL   A HG21 1 
ATOM   110  H HG22 . VAL   A 1 11  ? 32.42638 -3.17522  13.81976 1.000 21.99980  ? 8   VAL   A HG22 1 
ATOM   111  H HG23 . VAL   A 1 11  ? 31.37683 -2.20399  13.12791 1.000 21.99980  ? 8   VAL   A HG23 1 
ATOM   112  N N    . ILE   A 1 12  ? 29.19723 -6.72338  13.85816 1.000 22.31930  ? 9   ILE   A N    1 
ATOM   113  C CA   . ILE   A 1 12  ? 28.16025 -7.70084  14.17208 1.000 24.95951  ? 9   ILE   A CA   1 
ATOM   114  C C    . ILE   A 1 12  ? 28.22570 -7.99459  15.66359 1.000 24.81263  ? 9   ILE   A C    1 
ATOM   115  O O    . ILE   A 1 12  ? 29.23601 -8.50498  16.16245 1.000 24.02201  ? 9   ILE   A O    1 
ATOM   116  C CB   . ILE   A 1 12  ? 28.32432 -8.98267  13.33939 1.000 24.96235  ? 9   ILE   A CB   1 
ATOM   117  C CG1  . ILE   A 1 12  ? 28.28644 -8.64137  11.84635 1.000 26.11159  ? 9   ILE   A CG1  1 
ATOM   118  C CG2  . ILE   A 1 12  ? 27.23337 -9.99023  13.68851 1.000 27.58189  ? 9   ILE   A CG2  1 
ATOM   119  C CD1  . ILE   A 1 12  ? 28.42056 -9.83935  10.93201 1.000 27.98882  ? 9   ILE   A CD1  1 
ATOM   120  H H    . ILE   A 1 12  ? 29.97148 -7.07522  13.73028 1.000 26.71753  ? 9   ILE   A H    1 
ATOM   121  H HA   . ILE   A 1 12  ? 27.28913 -7.32278  13.97425 1.000 29.88578  ? 9   ILE   A HA   1 
ATOM   122  H HB   . ILE   A 1 12  ? 29.18366 -9.38161  13.54744 1.000 29.88919  ? 9   ILE   A HB   1 
ATOM   123  H HG12 . ILE   A 1 12  ? 27.43908 -8.21317  11.64758 1.000 31.26828  ? 9   ILE   A HG12 1 
ATOM   124  H HG13 . ILE   A 1 12  ? 29.01839 -8.03659  11.64788 1.000 31.26828  ? 9   ILE   A HG13 1 
ATOM   125  H HG21 . ILE   A 1 12  ? 27.38523 -10.80656 13.18707 1.000 33.03263  ? 9   ILE   A HG21 1 
ATOM   126  H HG22 . ILE   A 1 12  ? 27.26728 -10.17538 14.64007 1.000 33.03263  ? 9   ILE   A HG22 1 
ATOM   127  H HG23 . ILE   A 1 12  ? 26.37007 -9.61448  13.45521 1.000 33.03263  ? 9   ILE   A HG23 1 
ATOM   128  H HD11 . ILE   A 1 12  ? 28.60015 -9.52994  10.03040 1.000 33.52095  ? 9   ILE   A HD11 1 
ATOM   129  H HD12 . ILE   A 1 12  ? 29.15294 -10.39390 11.24346 1.000 33.52095  ? 9   ILE   A HD12 1 
ATOM   130  H HD13 . ILE   A 1 12  ? 27.59257 -10.34435 10.94965 1.000 33.52095  ? 9   ILE   A HD13 1 
ATOM   131  N N    . LEU   A 1 13  ? 27.14487 -7.68370  16.37267 1.000 25.62419  ? 10  LEU   A N    1 
ATOM   132  C CA   . LEU   A 1 13  ? 27.10574 -7.73406  17.82780 1.000 21.42092  ? 10  LEU   A CA   1 
ATOM   133  C C    . LEU   A 1 13  ? 26.15984 -8.84293  18.26916 1.000 24.45003  ? 10  LEU   A C    1 
ATOM   134  O O    . LEU   A 1 13  ? 24.95084 -8.76906  18.02295 1.000 27.34731  ? 10  LEU   A O    1 
ATOM   135  C CB   . LEU   A 1 13  ? 26.66760 -6.38431  18.39435 1.000 26.01882  ? 10  LEU   A CB   1 
ATOM   136  C CG   . LEU   A 1 13  ? 26.51307 -6.31238  19.91263 1.000 28.74939  ? 10  LEU   A CG   1 
ATOM   137  C CD1  . LEU   A 1 13  ? 27.80164 -6.72769  20.60790 1.000 32.03842  ? 10  LEU   A CD1  1 
ATOM   138  C CD2  . LEU   A 1 13  ? 26.10280 -4.91188  20.32640 1.000 29.13094  ? 10  LEU   A CD2  1 
ATOM   139  H H    . LEU   A 1 13  ? 26.40092 -7.43353  16.02117 1.000 30.68340  ? 10  LEU   A H    1 
ATOM   140  H HA   . LEU   A 1 13  ? 27.98781 -7.94535  18.17160 1.000 25.63947  ? 10  LEU   A HA   1 
ATOM   141  H HB2  . LEU   A 1 13  ? 27.32897 -5.72134  18.14145 1.000 31.15695  ? 10  LEU   A HB2  1 
ATOM   142  H HB3  . LEU   A 1 13  ? 25.80717 -6.15901  18.00730 1.000 31.15695  ? 10  LEU   A HB3  1 
ATOM   143  H HG   . LEU   A 1 13  ? 25.81900 -6.92917  20.19324 1.000 34.43364  ? 10  LEU   A HG   1 
ATOM   144  H HD11 . LEU   A 1 13  ? 27.72533 -6.53527  21.55556 1.000 38.38048  ? 10  LEU   A HD11 1 
ATOM   145  H HD12 . LEU   A 1 13  ? 27.94079 -7.67821  20.47353 1.000 38.38048  ? 10  LEU   A HD12 1 
ATOM   146  H HD13 . LEU   A 1 13  ? 28.54094 -6.22812  20.22742 1.000 38.38048  ? 10  LEU   A HD13 1 
ATOM   147  H HD21 . LEU   A 1 13  ? 25.95274 -4.89689  21.28461 1.000 34.89150  ? 10  LEU   A HD21 1 
ATOM   148  H HD22 . LEU   A 1 13  ? 26.81233 -4.29302  20.09299 1.000 34.89150  ? 10  LEU   A HD22 1 
ATOM   149  H HD23 . LEU   A 1 13  ? 25.28708 -4.67101  19.86004 1.000 34.89150  ? 10  LEU   A HD23 1 
ATOM   150  N N    . ALA   A 1 14  ? 26.71215 -9.86225  18.92250 1.000 22.79461  ? 11  ALA   A N    1 
ATOM   151  C CA   . ALA   A 1 14  ? 25.94554 -10.98442 19.43888 1.000 24.42076  ? 11  ALA   A CA   1 
ATOM   152  C C    . ALA   A 1 14  ? 26.07345 -11.04571 20.95525 1.000 28.07252  ? 11  ALA   A C    1 
ATOM   153  O O    . ALA   A 1 14  ? 27.03113 -10.53363 21.54206 1.000 24.19445  ? 11  ALA   A O    1 
ATOM   154  C CB   . ALA   A 1 14  ? 26.41733 -12.30996 18.82578 1.000 32.46014  ? 11  ALA   A CB   1 
ATOM   155  H H    . ALA   A 1 14  ? 27.55490 -9.92491  19.08203 1.000 27.28790  ? 11  ALA   A H    1 
ATOM   156  H HA   . ALA   A 1 14  ? 25.00934 -10.86191 19.21654 1.000 29.23929  ? 11  ALA   A HA   1 
ATOM   157  H HB1  . ALA   A 1 14  ? 25.88823 -13.03450 19.19457 1.000 38.88654  ? 11  ALA   A HB1  1 
ATOM   158  H HB2  . ALA   A 1 14  ? 26.30099 -12.27195 17.86353 1.000 38.88654  ? 11  ALA   A HB2  1 
ATOM   159  H HB3  . ALA   A 1 14  ? 27.35398 -12.44168 19.04078 1.000 38.88654  ? 11  ALA   A HB3  1 
ATOM   160  N N    . LYS   A 1 15  ? 25.09191 -11.68268 21.58885 1.000 25.84816  ? 12  LYS   A N    1 
ATOM   161  C CA   . LYS   A 1 15  ? 25.15526 -11.88278 23.02912 1.000 28.04240  ? 12  LYS   A CA   1 
ATOM   162  C C    . LYS   A 1 15  ? 26.45089 -12.59275 23.39630 1.000 23.21391  ? 12  LYS   A C    1 
ATOM   163  O O    . LYS   A 1 15  ? 26.90351 -13.49884 22.69182 1.000 22.90403  ? 12  LYS   A O    1 
ATOM   164  C CB   . LYS   A 1 15  ? 23.95529 -12.69763 23.51170 1.000 30.30734  ? 12  LYS   A CB   1 
ATOM   165  C CG   . LYS   A 1 15  ? 23.88026 -12.84986 25.02661 1.000 35.79155  ? 12  LYS   A CG   1 
ATOM   166  C CD   . LYS   A 1 15  ? 22.71341 -13.73132 25.44505 1.000 47.11434  ? 12  LYS   A CD   1 
ATOM   167  C CE   . LYS   A 1 15  ? 22.44359 -13.62960 26.94128 1.000 48.98597  ? 12  LYS   A CE   1 
ATOM   168  N NZ   . LYS   A 1 15  ? 23.61951 -14.02776 27.76639 1.000 59.47847  ? 12  LYS   A NZ   1 
ATOM   169  H H    . LYS   A 1 15  ? 24.38884 -12.00361 21.21164 1.000 30.95217  ? 12  LYS   A H    1 
ATOM   170  H HA   . LYS   A 1 15  ? 25.12930 -11.02303 23.47752 1.000 33.58525  ? 12  LYS   A HA   1 
ATOM   171  H HB2  . LYS   A 1 15  ? 23.14215 -12.25755 23.21840 1.000 36.30318  ? 12  LYS   A HB2  1 
ATOM   172  H HB3  . LYS   A 1 15  ? 24.00832 -13.58681 23.12772 1.000 36.30318  ? 12  LYS   A HB3  1 
ATOM   173  H HG2  . LYS   A 1 15  ? 24.69970 -13.25663 25.34904 1.000 42.88423  ? 12  LYS   A HG2  1 
ATOM   174  H HG3  . LYS   A 1 15  ? 23.76198 -11.97626 25.43126 1.000 42.88423  ? 12  LYS   A HG3  1 
ATOM   175  H HD2  . LYS   A 1 15  ? 21.91413 -13.45210 24.97168 1.000 56.47158  ? 12  LYS   A HD2  1 
ATOM   176  H HD3  . LYS   A 1 15  ? 22.91774 -14.65588 25.23450 1.000 56.47158  ? 12  LYS   A HD3  1 
ATOM   177  H HE2  . LYS   A 1 15  ? 22.22010 -12.71160 27.16091 1.000 58.71754  ? 12  LYS   A HE2  1 
ATOM   178  H HE3  . LYS   A 1 15  ? 21.70464 -14.21481 27.17015 1.000 58.71754  ? 12  LYS   A HE3  1 
ATOM   179  H HZ1  . LYS   A 1 15  ? 23.42804 -13.94079 28.63119 1.000 71.30854  ? 12  LYS   A HZ1  1 
ATOM   180  H HZ2  . LYS   A 1 15  ? 23.83371 -14.87578 27.60184 1.000 71.30854  ? 12  LYS   A HZ2  1 
ATOM   181  H HZ3  . LYS   A 1 15  ? 24.31717 -13.51062 27.57160 1.000 71.30854  ? 12  LYS   A HZ3  1 
ATOM   182  N N    . GLY   A 1 16  ? 27.04733 -12.17430 24.50876 1.000 24.51964  ? 13  GLY   A N    1 
ATOM   183  C CA   . GLY   A 1 16  ? 28.31122 -12.72009 24.94561 1.000 25.71265  ? 13  GLY   A CA   1 
ATOM   184  C C    . GLY   A 1 16  ? 29.52762 -12.10404 24.29496 1.000 18.80261  ? 13  GLY   A C    1 
ATOM   185  O O    . GLY   A 1 16  ? 30.64976 -12.53011 24.59528 1.000 25.16969  ? 13  GLY   A O    1 
ATOM   186  H H    . GLY   A 1 16  ? 26.73016 -11.56744 25.02906 1.000 29.35794  ? 13  GLY   A H    1 
ATOM   187  H HA2  . GLY   A 1 16  ? 28.39075 -12.59097 25.90368 1.000 30.78956  ? 13  GLY   A HA2  1 
ATOM   188  H HA3  . GLY   A 1 16  ? 28.32215 -13.67073 24.75309 1.000 30.78956  ? 13  GLY   A HA3  1 
ATOM   189  N N    . ALA   A 1 17  ? 29.34565 -11.12330 23.41330 1.000 19.82905  ? 14  ALA   A N    1 
ATOM   190  C CA   . ALA   A 1 17  ? 30.47719 -10.42830 22.81925 1.000 22.35987  ? 14  ALA   A CA   1 
ATOM   191  C C    . ALA   A 1 17  ? 31.25862 -9.67471  23.88880 1.000 25.00359  ? 14  ALA   A C    1 
ATOM   192  O O    . ALA   A 1 17  ? 30.71260 -9.25949  24.91393 1.000 19.27953  ? 14  ALA   A O    1 
ATOM   193  C CB   . ALA   A 1 17  ? 29.99644 -9.45596  21.74280 1.000 24.03302  ? 14  ALA   A CB   1 
ATOM   194  H H    . ALA   A 1 17  ? 28.57809 -10.84368 23.14447 1.000 23.72923  ? 14  ALA   A H    1 
ATOM   195  H HA   . ALA   A 1 17  ? 31.07048 -11.07278 22.40265 1.000 26.76622  ? 14  ALA   A HA   1 
ATOM   196  H HB1  . ALA   A 1 17  ? 30.76453 -9.00455  21.35919 1.000 28.77400  ? 14  ALA   A HB1  1 
ATOM   197  H HB2  . ALA   A 1 17  ? 29.52735 -9.95333  21.05471 1.000 28.77400  ? 14  ALA   A HB2  1 
ATOM   198  H HB3  . ALA   A 1 17  ? 29.39938 -8.80718  22.14716 1.000 28.77400  ? 14  ALA   A HB3  1 
ATOM   199  N N    . GLU   A 1 18  ? 32.55478 -9.50443  23.64383 1.000 18.33281  ? 15  GLU   A N    1 
ATOM   200  C CA   . GLU   A 1 18  ? 33.41174 -8.73749  24.54150 1.000 17.90983  ? 15  GLU   A CA   1 
ATOM   201  C C    . GLU   A 1 18  ? 33.16764 -7.25598  24.28054 1.000 21.30208  ? 15  GLU   A C    1 
ATOM   202  O O    . GLU   A 1 18  ? 33.50199 -6.74314  23.20655 1.000 19.16204  ? 15  GLU   A O    1 
ATOM   203  C CB   . GLU   A 1 18  ? 34.87545 -9.10879  24.33156 1.000 19.20855  ? 15  GLU   A CB   1 
ATOM   204  C CG   . GLU   A 1 18  ? 35.66203 -9.24664  25.62269 1.000 21.34364  ? 15  GLU   A CG   1 
ATOM   205  C CD   . GLU   A 1 18  ? 35.65339 -7.98083  26.45423 1.000 23.42263  ? 15  GLU   A CD   1 
ATOM   206  O OE1  . GLU   A 1 18  ? 35.62320 -6.87860  25.86969 1.000 18.13468  ? 15  GLU   A OE1  1 
ATOM   207  O OE2  . GLU   A 1 18  ? 35.67480 -8.09258  27.69650 1.000 22.44080  ? 15  GLU   A OE2  1 
ATOM   208  H H    . GLU   A 1 18  ? 32.96418 -9.82567  22.95914 1.000 21.93375  ? 15  GLU   A H    1 
ATOM   209  H HA   . GLU   A 1 18  ? 33.18660 -8.93465  25.46418 1.000 21.42617  ? 15  GLU   A HA   1 
ATOM   210  H HB2  . GLU   A 1 18  ? 34.91795 -9.95901  23.86655 1.000 22.98464  ? 15  GLU   A HB2  1 
ATOM   211  H HB3  . GLU   A 1 18  ? 35.29921 -8.41775  23.79883 1.000 22.98464  ? 15  GLU   A HB3  1 
ATOM   212  H HG2  . GLU   A 1 18  ? 35.27262 -9.95767  26.15532 1.000 25.54674  ? 15  GLU   A HG2  1 
ATOM   213  H HG3  . GLU   A 1 18  ? 36.58423 -9.45878  25.40953 1.000 25.54674  ? 15  GLU   A HG3  1 
ATOM   214  N N    . GLU   A 1 19  ? 32.58235 -6.56441  25.26317 1.000 19.68834  ? 16  GLU   A N    1 
ATOM   215  C CA   . GLU   A 1 19  ? 32.12783 -5.19732  25.02691 1.000 22.16769  ? 16  GLU   A CA   1 
ATOM   216  C C    . GLU   A 1 19  ? 33.28590 -4.24838  24.74201 1.000 16.05146  ? 16  GLU   A C    1 
ATOM   217  O O    . GLU   A 1 19  ? 33.12353 -3.29725  23.97098 1.000 18.55115  ? 16  GLU   A O    1 
ATOM   218  C CB   . GLU   A 1 19  ? 31.30644 -4.68558  26.21511 1.000 17.97037  ? 16  GLU   A CB   1 
ATOM   219  C CG   . GLU   A 1 19  ? 31.85439 -5.02761  27.58989 1.000 17.53203  ? 16  GLU   A CG   1 
ATOM   220  C CD   . GLU   A 1 19  ? 31.30458 -6.33829  28.11962 1.000 22.43843  ? 16  GLU   A CD   1 
ATOM   221  O OE1  . GLU   A 1 19  ? 31.77381 -7.40342  27.66948 1.000 20.45558  ? 16  GLU   A OE1  1 
ATOM   222  O OE2  . GLU   A 1 19  ? 30.39121 -6.30401  28.97149 1.000 20.95677  ? 16  GLU   A OE2  1 
ATOM   223  H H    . GLU   A 1 19  ? 32.44047 -6.85946  26.05841 1.000 23.56038  ? 16  GLU   A H    1 
ATOM   224  H HA   . GLU   A 1 19  ? 31.54963 -5.20636  24.24813 1.000 26.53560  ? 16  GLU   A HA   1 
ATOM   225  H HB2  . GLU   A 1 19  ? 31.25728 -3.71856  26.15715 1.000 21.49881  ? 16  GLU   A HB2  1 
ATOM   226  H HB3  . GLU   A 1 19  ? 30.41653 -5.06710  26.15675 1.000 21.49881  ? 16  GLU   A HB3  1 
ATOM   227  H HG2  . GLU   A 1 19  ? 32.81986 -5.10479  27.53695 1.000 20.97280  ? 16  GLU   A HG2  1 
ATOM   228  H HG3  . GLU   A 1 19  ? 31.61141 -4.32476  28.21267 1.000 20.97280  ? 16  GLU   A HG3  1 
ATOM   229  N N    . MET   A 1 20  ? 34.45428 -4.47783  25.34490 1.000 21.70336  ? 17  MET   A N    1 
ATOM   230  C CA   . MET   A 1 20  ? 35.60458 -3.63578  25.03330 1.000 20.29472  ? 17  MET   A CA   1 
ATOM   231  C C    . MET   A 1 20  ? 36.02544 -3.80768  23.57966 1.000 21.72860  ? 17  MET   A C    1 
ATOM   232  O O    . MET   A 1 20  ? 36.34664 -2.82818  22.89660 1.000 17.81533  ? 17  MET   A O    1 
ATOM   233  C CB   . MET   A 1 20  ? 36.77307 -3.96127  25.96337 1.000 15.97147  ? 17  MET   A CB   1 
ATOM   234  C CG   . MET   A 1 20  ? 36.51033 -3.66488  27.42961 1.000 21.05309  ? 17  MET   A CG   1 
ATOM   235  S SD   . MET   A 1 20  ? 37.98306 -3.87081  28.45068 1.000 24.60102  ? 17  MET   A SD   1 
ATOM   236  C CE   . MET   A 1 20  ? 38.17603 -5.65154  28.45665 1.000 21.57971  ? 17  MET   A CE   1 
ATOM   237  H H    . MET   A 1 20  ? 34.60185 -5.09802  25.92213 1.000 25.97840  ? 17  MET   A H    1 
ATOM   238  H HA   . MET   A 1 20  ? 35.35596 -2.71094  25.18743 1.000 24.28804  ? 17  MET   A HA   1 
ATOM   239  H HB2  . MET   A 1 20  ? 36.97491 -4.90695  25.88693 1.000 19.10014  ? 17  MET   A HB2  1 
ATOM   240  H HB3  . MET   A 1 20  ? 37.54100 -3.43505  25.69084 1.000 19.10014  ? 17  MET   A HB3  1 
ATOM   241  H HG2  . MET   A 1 20  ? 36.20840 -2.74736  27.51840 1.000 25.19808  ? 17  MET   A HG2  1 
ATOM   242  H HG3  . MET   A 1 20  ? 35.82879 -4.27171  27.75850 1.000 25.19808  ? 17  MET   A HG3  1 
ATOM   243  H HE1  . MET   A 1 20  ? 37.79548 -6.00769  29.27472 1.000 25.83003  ? 17  MET   A HE1  1 
ATOM   244  H HE2  . MET   A 1 20  ? 37.71402 -6.02184  27.68832 1.000 25.83003  ? 17  MET   A HE2  1 
ATOM   245  H HE3  . MET   A 1 20  ? 39.12065 -5.86698  28.41007 1.000 25.83003  ? 17  MET   A HE3  1 
ATOM   246  N N    . GLU   A 1 21  ? 36.03332 -5.04919  23.09152 1.000 22.45428  ? 18  GLU   A N    1 
ATOM   247  C CA   . GLU   A 1 21  ? 36.39285 -5.32776  21.70733 1.000 23.01292  ? 18  GLU   A CA   1 
ATOM   248  C C    . GLU   A 1 21  ? 35.34281 -4.84177  20.72063 1.000 25.31900  ? 18  GLU   A C    1 
ATOM   249  O O    . GLU   A 1 21  ? 35.61356 -4.81417  19.51507 1.000 19.28080  ? 18  GLU   A O    1 
ATOM   250  C CB   . GLU   A 1 21  ? 36.61907 -6.82866  21.53255 1.000 23.51031  ? 18  GLU   A CB   1 
ATOM   251  C CG   . GLU   A 1 21  ? 37.73651 -7.36653  22.40745 1.000 23.87250  ? 18  GLU   A CG   1 
ATOM   252  C CD   . GLU   A 1 21  ? 37.82776 -8.87542  22.38056 1.000 25.39746  ? 18  GLU   A CD   1 
ATOM   253  O OE1  . GLU   A 1 21  ? 37.15259 -9.49823  21.53661 1.000 23.05472  ? 18  GLU   A OE1  1 
ATOM   254  O OE2  . GLU   A 1 21  ? 38.57523 -9.43620  23.20741 1.000 21.79473  ? 18  GLU   A OE2  1 
ATOM   255  H H    . GLU   A 1 21  ? 35.83255 -5.75049  23.54699 1.000 26.87951  ? 18  GLU   A H    1 
ATOM   256  H HA   . GLU   A 1 21  ? 37.22278 -4.87190  21.49684 1.000 27.54988  ? 18  GLU   A HA   1 
ATOM   257  H HB2  . GLU   A 1 21  ? 35.80349 -7.29902  21.76597 1.000 28.14675  ? 18  GLU   A HB2  1 
ATOM   258  H HB3  . GLU   A 1 21  ? 36.85133 -7.00620  20.60766 1.000 28.14675  ? 18  GLU   A HB3  1 
ATOM   259  H HG2  . GLU   A 1 21  ? 38.58238 -7.00955  22.09446 1.000 28.58137  ? 18  GLU   A HG2  1 
ATOM   260  H HG3  . GLU   A 1 21  ? 37.57959 -7.09211  23.32450 1.000 28.58137  ? 18  GLU   A HG3  1 
ATOM   261  N N    . THR   A 1 22  ? 34.15929 -4.46749  21.19891 1.000 22.24171  ? 19  THR   A N    1 
ATOM   262  C CA   . THR   A 1 22  ? 33.12006 -3.90715  20.34773 1.000 23.49984  ? 19  THR   A CA   1 
ATOM   263  C C    . THR   A 1 22  ? 33.18865 -2.38434  20.31903 1.000 24.02736  ? 19  THR   A C    1 
ATOM   264  O O    . THR   A 1 22  ? 33.15130 -1.77696  19.24453 1.000 21.92189  ? 19  THR   A O    1 
ATOM   265  C CB   . THR   A 1 22  ? 31.74303 -4.36746  20.83884 1.000 27.17156  ? 19  THR   A CB   1 
ATOM   266  O OG1  . THR   A 1 22  ? 31.67903 -5.79897  20.81235 1.000 21.22295  ? 19  THR   A OG1  1 
ATOM   267  C CG2  . THR   A 1 22  ? 30.63516 -3.80150  19.96685 1.000 28.43014  ? 19  THR   A CG2  1 
ATOM   268  H H    . THR   A 1 22  ? 33.93221 -4.52971  22.02605 1.000 26.62442  ? 19  THR   A H    1 
ATOM   269  H HA   . THR   A 1 22  ? 33.23811 -4.23343  19.44191 1.000 28.13418  ? 19  THR   A HA   1 
ATOM   270  H HB   . THR   A 1 22  ? 31.60594 -4.04921  21.74484 1.000 32.54024  ? 19  THR   A HB   1 
ATOM   271  H HG1  . THR   A 1 22  ? 32.28958 -6.12274  21.28984 1.000 25.40191  ? 19  THR   A HG1  1 
ATOM   272  H HG21 . THR   A 1 22  ? 29.79607 -4.24509  20.16700 1.000 34.05054  ? 19  THR   A HG21 1 
ATOM   273  H HG22 . THR   A 1 22  ? 30.53588 -2.85083  20.13200 1.000 34.05054  ? 19  THR   A HG22 1 
ATOM   274  H HG23 . THR   A 1 22  ? 30.84773 -3.93780  19.03030 1.000 34.05054  ? 19  THR   A HG23 1 
ATOM   275  N N    . VAL   A 1 23  ? 33.31714 -1.76043  21.49095 1.000 23.30261  ? 20  VAL   A N    1 
ATOM   276  C CA   . VAL   A 1 23  ? 33.19865 -0.30946  21.58433 1.000 20.77743  ? 20  VAL   A CA   1 
ATOM   277  C C    . VAL   A 1 23  ? 34.45138 0.38349   21.06406 1.000 21.10275  ? 20  VAL   A C    1 
ATOM   278  O O    . VAL   A 1 23  ? 34.36541 1.42030   20.39726 1.000 19.64582  ? 20  VAL   A O    1 
ATOM   279  C CB   . VAL   A 1 23  ? 32.88943 0.09507   23.03644 1.000 25.95580  ? 20  VAL   A CB   1 
ATOM   280  C CG1  . VAL   A 1 23  ? 32.97386 1.60531   23.19610 1.000 32.44710  ? 20  VAL   A CG1  1 
ATOM   281  C CG2  . VAL   A 1 23  ? 31.51596 -0.41916  23.44125 1.000 23.39917  ? 20  VAL   A CG2  1 
ATOM   282  H H    . VAL   A 1 23  ? 33.47202 -2.15264  22.24048 1.000 27.89750  ? 20  VAL   A H    1 
ATOM   283  H HA   . VAL   A 1 23  ? 32.45957 -0.02743  21.02298 1.000 24.86729  ? 20  VAL   A HA   1 
ATOM   284  H HB   . VAL   A 1 23  ? 33.54755 -0.30316  23.62736 1.000 31.08133  ? 20  VAL   A HB   1 
ATOM   285  H HG11 . VAL   A 1 23  ? 33.90459 1.86122   23.29176 1.000 38.87090  ? 20  VAL   A HG11 1 
ATOM   286  H HG12 . VAL   A 1 23  ? 32.59378 2.02772   22.40995 1.000 38.87090  ? 20  VAL   A HG12 1 
ATOM   287  H HG13 . VAL   A 1 23  ? 32.47578 1.86770   23.98602 1.000 38.87090  ? 20  VAL   A HG13 1 
ATOM   288  H HG21 . VAL   A 1 23  ? 31.26628 -0.01929  24.28899 1.000 28.01337  ? 20  VAL   A HG21 1 
ATOM   289  H HG22 . VAL   A 1 23  ? 30.87287 -0.17398  22.75771 1.000 28.01337  ? 20  VAL   A HG22 1 
ATOM   290  H HG23 . VAL   A 1 23  ? 31.55345 -1.38445  23.52913 1.000 28.01337  ? 20  VAL   A HG23 1 
ATOM   291  N N    . ILE   A 1 24  ? 35.63222 -0.16194  21.35711 1.000 22.22748  ? 21  ILE   A N    1 
ATOM   292  C CA   . ILE   A 1 24  ? 36.86736 0.49167   20.92660 1.000 19.95239  ? 21  ILE   A CA   1 
ATOM   293  C C    . ILE   A 1 24  ? 36.93097 0.62112   19.40905 1.000 16.72382  ? 21  ILE   A C    1 
ATOM   294  O O    . ILE   A 1 24  ? 37.16033 1.73735   18.91603 1.000 18.85163  ? 21  ILE   A O    1 
ATOM   295  C CB   . ILE   A 1 24  ? 38.08696 -0.24233  21.51467 1.000 18.37146  ? 21  ILE   A CB   1 
ATOM   296  C CG1  . ILE   A 1 24  ? 38.14071 -0.03544  23.03112 1.000 24.44444  ? 21  ILE   A CG1  1 
ATOM   297  C CG2  . ILE   A 1 24  ? 39.37204 0.24959   20.85831 1.000 17.77429  ? 21  ILE   A CG2  1 
ATOM   298  C CD1  . ILE   A 1 24  ? 39.15189 -0.91459  23.72956 1.000 22.12251  ? 21  ILE   A CD1  1 
ATOM   299  H H    . ILE   A 1 24  ? 35.74396 -0.89394  21.79448 1.000 26.60735  ? 21  ILE   A H    1 
ATOM   300  H HA   . ILE   A 1 24  ? 36.86824 1.38800   21.29740 1.000 23.87724  ? 21  ILE   A HA   1 
ATOM   301  H HB   . ILE   A 1 24  ? 37.99643 -1.19095  21.33353 1.000 21.98012  ? 21  ILE   A HB   1 
ATOM   302  H HG12 . ILE   A 1 24  ? 38.37628 0.88801   23.21182 1.000 29.26770  ? 21  ILE   A HG12 1 
ATOM   303  H HG13 . ILE   A 1 24  ? 37.26768 -0.23422  23.40422 1.000 29.26770  ? 21  ILE   A HG13 1 
ATOM   304  H HG21 . ILE   A 1 24  ? 40.13077 -0.06649  21.37341 1.000 21.26352  ? 21  ILE   A HG21 1 
ATOM   305  H HG22 . ILE   A 1 24  ? 39.41807 -0.09844  19.95407 1.000 21.26352  ? 21  ILE   A HG22 1 
ATOM   306  H HG23 . ILE   A 1 24  ? 39.36589 1.21939   20.83957 1.000 21.26352  ? 21  ILE   A HG23 1 
ATOM   307  H HD11 . ILE   A 1 24  ? 38.95877 -0.92434  24.68009 1.000 26.48138  ? 21  ILE   A HD11 1 
ATOM   308  H HD12 . ILE   A 1 24  ? 39.09040 -1.81350  23.37029 1.000 26.48138  ? 21  ILE   A HD12 1 
ATOM   309  H HD13 . ILE   A 1 24  ? 40.04049 -0.55714  23.57621 1.000 26.48138  ? 21  ILE   A HD13 1 
ATOM   310  N N    . PRO   A 1 25  ? 36.73764 -0.44033  18.61912 1.000 17.31811  ? 22  PRO   A N    1 
ATOM   311  C CA   . PRO   A 1 25  ? 36.78448 -0.25642  17.15858 1.000 22.03153  ? 22  PRO   A CA   1 
ATOM   312  C C    . PRO   A 1 25  ? 35.67997 0.64328   16.63349 1.000 17.72352  ? 22  PRO   A C    1 
ATOM   313  O O    . PRO   A 1 25  ? 35.92389 1.45147   15.72953 1.000 20.26596  ? 22  PRO   A O    1 
ATOM   314  C CB   . PRO   A 1 25  ? 36.66070 -1.69000  16.62132 1.000 19.80608  ? 22  PRO   A CB   1 
ATOM   315  C CG   . PRO   A 1 25  ? 37.07131 -2.56510  17.75707 1.000 24.25214  ? 22  PRO   A CG   1 
ATOM   316  C CD   . PRO   A 1 25  ? 36.58890 -1.85929  18.98228 1.000 21.10560  ? 22  PRO   A CD   1 
ATOM   317  H HA   . PRO   A 1 25  ? 37.64536 0.10842   16.90037 1.000 26.37220  ? 22  PRO   A HA   1 
ATOM   318  H HB2  . PRO   A 1 25  ? 35.74318 -1.86686  16.36100 1.000 23.70167  ? 22  PRO   A HB2  1 
ATOM   319  H HB3  . PRO   A 1 25  ? 37.25033 -1.80938  15.86041 1.000 23.70167  ? 22  PRO   A HB3  1 
ATOM   320  H HG2  . PRO   A 1 25  ? 36.65316 -3.43614  17.67140 1.000 29.03694  ? 22  PRO   A HG2  1 
ATOM   321  H HG3  . PRO   A 1 25  ? 38.03656 -2.66022  17.76911 1.000 29.03694  ? 22  PRO   A HG3  1 
ATOM   322  H HD2  . PRO   A 1 25  ? 35.66119 -2.07563  19.16519 1.000 25.26109  ? 22  PRO   A HD2  1 
ATOM   323  H HD3  . PRO   A 1 25  ? 37.13882 -2.08085  19.75000 1.000 25.26109  ? 22  PRO   A HD3  1 
ATOM   324  N N    . VAL   A 1 26  ? 34.46511 0.52412   17.17243 1.000 18.32218  ? 23  VAL   A N    1 
ATOM   325  C CA   . VAL   A 1 26  ? 33.37501 1.39744   16.74315 1.000 19.25651  ? 23  VAL   A CA   1 
ATOM   326  C C    . VAL   A 1 26  ? 33.74043 2.85297   16.99637 1.000 18.75331  ? 23  VAL   A C    1 
ATOM   327  O O    . VAL   A 1 26  ? 33.62710 3.71119   16.11200 1.000 20.78062  ? 23  VAL   A O    1 
ATOM   328  C CB   . VAL   A 1 26  ? 32.06954 1.01663   17.46320 1.000 18.07342  ? 23  VAL   A CB   1 
ATOM   329  C CG1  . VAL   A 1 26  ? 31.02095 2.10436   17.27349 1.000 21.80043  ? 23  VAL   A CG1  1 
ATOM   330  C CG2  . VAL   A 1 26  ? 31.55670 -0.32178  16.96242 1.000 20.06853  ? 23  VAL   A CG2  1 
ATOM   331  H H    . VAL   A 1 26  ? 34.24972 -0.04597  17.77923 1.000 21.92099  ? 23  VAL   A H    1 
ATOM   332  H HA   . VAL   A 1 26  ? 33.23986 1.27929   15.78991 1.000 23.04218  ? 23  VAL   A HA   1 
ATOM   333  H HB   . VAL   A 1 26  ? 32.24632 0.93251   18.41324 1.000 21.62248  ? 23  VAL   A HB   1 
ATOM   334  H HG11 . VAL   A 1 26  ? 30.14186 1.72691   17.43357 1.000 26.09489  ? 23  VAL   A HG11 1 
ATOM   335  H HG12 . VAL   A 1 26  ? 31.19260 2.82179   17.90336 1.000 26.09489  ? 23  VAL   A HG12 1 
ATOM   336  H HG13 . VAL   A 1 26  ? 31.07598 2.44115   16.36550 1.000 26.09489  ? 23  VAL   A HG13 1 
ATOM   337  H HG21 . VAL   A 1 26  ? 30.74661 -0.55005  17.44465 1.000 24.01660  ? 23  VAL   A HG21 1 
ATOM   338  H HG22 . VAL   A 1 26  ? 31.36838 -0.25278  16.01338 1.000 24.01660  ? 23  VAL   A HG22 1 
ATOM   339  H HG23 . VAL   A 1 26  ? 32.23509 -0.99770  17.11674 1.000 24.01660  ? 23  VAL   A HG23 1 
ATOM   340  N N    . ASP   A 1 27  ? 34.18615 3.14633   18.21658 1.000 19.72116  ? 24  ASP   A N    1 
ATOM   341  C CA   . ASP   A 1 27  ? 34.57090 4.50509   18.57683 1.000 18.66811  ? 24  ASP   A CA   1 
ATOM   342  C C    . ASP   A 1 27  ? 35.69450 5.01036   17.67939 1.000 18.94314  ? 24  ASP   A C    1 
ATOM   343  O O    . ASP   A 1 27  ? 35.58107 6.07164   17.05443 1.000 17.85753  ? 24  ASP   A O    1 
ATOM   344  C CB   . ASP   A 1 27  ? 34.98723 4.52405   20.04932 1.000 22.16463  ? 24  ASP   A CB   1 
ATOM   345  C CG   . ASP   A 1 27  ? 35.19388 5.91972   20.58748 1.000 23.55712  ? 24  ASP   A CG   1 
ATOM   346  O OD1  . ASP   A 1 27  ? 35.81635 6.75095   19.89358 1.000 21.64731  ? 24  ASP   A OD1  1 
ATOM   347  O OD2  . ASP   A 1 27  ? 34.73362 6.17808   21.71847 1.000 24.64872  ? 24  ASP   A OD2  1 
ATOM   348  H H    . ASP   A 1 27  ? 34.27494 2.57581   18.85394 1.000 23.59977  ? 24  ASP   A H    1 
ATOM   349  H HA   . ASP   A 1 27  ? 33.81670 5.10399   18.46107 1.000 22.33610  ? 24  ASP   A HA   1 
ATOM   350  H HB2  . ASP   A 1 27  ? 34.29365 4.09966   20.57821 1.000 26.53192  ? 24  ASP   A HB2  1 
ATOM   351  H HB3  . ASP   A 1 27  ? 35.82197 4.03970   20.14687 1.000 26.53192  ? 24  ASP   A HB3  1 
ATOM   352  N N    . VAL   A 1 28  ? 36.78481 4.24872   17.58970 1.000 21.27642  ? 25  VAL   A N    1 
ATOM   353  C CA   . VAL   A 1 28  ? 37.94533 4.69675   16.82714 1.000 22.07029  ? 25  VAL   A CA   1 
ATOM   354  C C    . VAL   A 1 28  ? 37.58867 4.87457   15.35733 1.000 20.33992  ? 25  VAL   A C    1 
ATOM   355  O O    . VAL   A 1 28  ? 38.03362 5.82892   14.70805 1.000 21.35914  ? 25  VAL   A O    1 
ATOM   356  C CB   . VAL   A 1 28  ? 39.11070 3.70843   17.01346 1.000 23.63190  ? 25  VAL   A CB   1 
ATOM   357  C CG1  . VAL   A 1 28  ? 40.22662 4.00407   16.02445 1.000 25.93701  ? 25  VAL   A CG1  1 
ATOM   358  C CG2  . VAL   A 1 28  ? 39.62233 3.76867   18.44778 1.000 22.86680  ? 25  VAL   A CG2  1 
ATOM   359  H H    . VAL   A 1 28  ? 36.87633 3.47672   17.95743 1.000 25.46608  ? 25  VAL   A H    1 
ATOM   360  H HA   . VAL   A 1 28  ? 38.22293 5.56160   17.16755 1.000 26.41872  ? 25  VAL   A HA   1 
ATOM   361  H HB   . VAL   A 1 28  ? 38.79590 2.80732   16.84083 1.000 28.29266  ? 25  VAL   A HB   1 
ATOM   362  H HG11 . VAL   A 1 28  ? 41.03921 3.56832   16.32565 1.000 31.05878  ? 25  VAL   A HG11 1 
ATOM   363  H HG12 . VAL   A 1 28  ? 39.97328 3.66474   15.15176 1.000 31.05878  ? 25  VAL   A HG12 1 
ATOM   364  H HG13 . VAL   A 1 28  ? 40.36286 4.96340   15.97954 1.000 31.05878  ? 25  VAL   A HG13 1 
ATOM   365  H HG21 . VAL   A 1 28  ? 40.37149 3.15969   18.54168 1.000 27.37453  ? 25  VAL   A HG21 1 
ATOM   366  H HG22 . VAL   A 1 28  ? 39.90634 4.67517   18.64396 1.000 27.37453  ? 25  VAL   A HG22 1 
ATOM   367  H HG23 . VAL   A 1 28  ? 38.90722 3.50858   19.04934 1.000 27.37453  ? 25  VAL   A HG23 1 
ATOM   368  N N    . MET   A 1 29  ? 36.78574 3.96261   14.80546 1.000 19.70857  ? 26  MET   A N    1 
ATOM   369  C CA   . MET   A 1 29  ? 36.42858 4.07370   13.39512 1.000 20.87210  ? 26  MET   A CA   1 
ATOM   370  C C    . MET   A 1 29  ? 35.57904 5.31170   13.13888 1.000 21.45120  ? 26  MET   A C    1 
ATOM   371  O O    . MET   A 1 29  ? 35.76371 5.99773   12.12654 1.000 23.48707  ? 26  MET   A O    1 
ATOM   372  C CB   . MET   A 1 29  ? 35.70046 2.81245   12.93069 1.000 20.51146  ? 26  MET   A CB   1 
ATOM   373  C CG   . MET   A 1 29  ? 36.63789 1.65368   12.61457 1.000 22.44802  ? 26  MET   A CG   1 
ATOM   374  S SD   . MET   A 1 29  ? 35.84146 0.29245   11.73977 1.000 22.04507  ? 26  MET   A SD   1 
ATOM   375  C CE   . MET   A 1 29  ? 34.76120 -0.35261  13.01111 1.000 18.11883  ? 26  MET   A CE   1 
ATOM   376  H H    . MET   A 1 29  ? 36.44424 3.28849   15.21600 1.000 23.58465  ? 26  MET   A H    1 
ATOM   377  H HA   . MET   A 1 29  ? 37.24562 4.14444   12.87709 1.000 24.98089  ? 26  MET   A HA   1 
ATOM   378  H HB2  . MET   A 1 29  ? 35.09621 2.52347   13.63231 1.000 24.54813  ? 26  MET   A HB2  1 
ATOM   379  H HB3  . MET   A 1 29  ? 35.19990 3.01837   12.12575 1.000 24.54813  ? 26  MET   A HB3  1 
ATOM   380  H HG2  . MET   A 1 29  ? 37.36126 1.98049   12.05704 1.000 26.87200  ? 26  MET   A HG2  1 
ATOM   381  H HG3  . MET   A 1 29  ? 36.99262 1.30319   13.44657 1.000 26.87200  ? 26  MET   A HG3  1 
ATOM   382  H HE1  . MET   A 1 29  ? 34.26519 -1.10499  12.65222 1.000 21.67697  ? 26  MET   A HE1  1 
ATOM   383  H HE2  . MET   A 1 29  ? 35.29832 -0.64028  13.76586 1.000 21.67697  ? 26  MET   A HE2  1 
ATOM   384  H HE3  . MET   A 1 29  ? 34.14790 0.34577   13.28865 1.000 21.67697  ? 26  MET   A HE3  1 
ATOM   385  N N    . ARG   A 1 30  ? 34.64607 5.61965   14.04308 1.000 17.58825  ? 27  ARG   A N    1 
ATOM   386  C CA   . ARG   A 1 30  ? 33.84848 6.82938   13.87364 1.000 19.57614  ? 27  ARG   A CA   1 
ATOM   387  C C    . ARG   A 1 30  ? 34.69914 8.08168   14.04093 1.000 20.11318  ? 27  ARG   A C    1 
ATOM   388  O O    . ARG   A 1 30  ? 34.43776 9.09664   13.38527 1.000 25.35901  ? 27  ARG   A O    1 
ATOM   389  C CB   . ARG   A 1 30  ? 32.67178 6.82345   14.84959 1.000 17.99985  ? 27  ARG   A CB   1 
ATOM   390  C CG   . ARG   A 1 30  ? 31.56830 5.86395   14.42488 1.000 24.31597  ? 27  ARG   A CG   1 
ATOM   391  C CD   . ARG   A 1 30  ? 30.41803 5.78704   15.41744 1.000 20.77922  ? 27  ARG   A CD   1 
ATOM   392  N NE   . ARG   A 1 30  ? 29.33767 4.95899   14.89204 1.000 27.02661  ? 27  ARG   A NE   1 
ATOM   393  C CZ   . ARG   A 1 30  ? 28.39338 4.38667   15.62692 1.000 25.15260  ? 27  ARG   A CZ   1 
ATOM   394  N NH1  . ARG   A 1 30  ? 28.35733 4.52718   16.94262 1.000 22.45436  ? 27  ARG   A NH1  1 
ATOM   395  N NH2  . ARG   A 1 30  ? 27.46489 3.64728   15.02653 1.000 24.73804  ? 27  ARG   A NH2  1 
ATOM   396  H H    . ARG   A 1 30  ? 34.46166 5.15632   14.74374 1.000 21.04027  ? 27  ARG   A H    1 
ATOM   397  H HA   . ARG   A 1 30  ? 33.47767 6.84575   12.97747 1.000 23.42574  ? 27  ARG   A HA   1 
ATOM   398  H HB2  . ARG   A 1 30  ? 32.98787 6.55100   15.72523 1.000 21.53420  ? 27  ARG   A HB2  1 
ATOM   399  H HB3  . ARG   A 1 30  ? 32.29424 7.71576   14.89600 1.000 21.53420  ? 27  ARG   A HB3  1 
ATOM   400  H HG2  . ARG   A 1 30  ? 31.20683 6.15812   13.57417 1.000 29.11354  ? 27  ARG   A HG2  1 
ATOM   401  H HG3  . ARG   A 1 30  ? 31.94338 4.97383   14.33599 1.000 29.11354  ? 27  ARG   A HG3  1 
ATOM   402  H HD2  . ARG   A 1 30  ? 30.73167 5.39471   16.24726 1.000 24.86944  ? 27  ARG   A HD2  1 
ATOM   403  H HD3  . ARG   A 1 30  ? 30.07166 6.67806   15.58182 1.000 24.86944  ? 27  ARG   A HD3  1 
ATOM   404  H HE   . ARG   A 1 30  ? 29.31115 4.83247   14.04181 1.000 32.36630  ? 27  ARG   A HE   1 
ATOM   405  H HH11 . ARG   A 1 30  ? 28.95580 4.99890   17.34125 1.000 26.87961  ? 27  ARG   A HH11 1 
ATOM   406  H HH12 . ARG   A 1 30  ? 27.73542 4.14675   17.39881 1.000 26.87961  ? 27  ARG   A HH12 1 
ATOM   407  H HH21 . ARG   A 1 30  ? 27.48205 3.54547   14.17275 1.000 29.62003  ? 27  ARG   A HH21 1 
ATOM   408  H HH22 . ARG   A 1 30  ? 26.84742 3.27105   15.49212 1.000 29.62003  ? 27  ARG   A HH22 1 
ATOM   409  N N    . ARG   A 1 31  ? 35.72662 8.02920   14.89278 1.000 23.17703  ? 28  ARG   A N    1 
ATOM   410  C CA   . ARG   A 1 31  ? 36.67303 9.13653   14.96028 1.000 20.49825  ? 28  ARG   A CA   1 
ATOM   411  C C    . ARG   A 1 31  ? 37.36569 9.35258   13.62277 1.000 22.85667  ? 28  ARG   A C    1 
ATOM   412  O O    . ARG   A 1 31  ? 37.74154 10.48344  13.29372 1.000 19.89611  ? 28  ARG   A O    1 
ATOM   413  C CB   . ARG   A 1 31  ? 37.71478 8.88136   16.04818 1.000 18.01775  ? 28  ARG   A CB   1 
ATOM   414  C CG   . ARG   A 1 31  ? 37.20947 9.08603   17.45854 1.000 22.01439  ? 28  ARG   A CG   1 
ATOM   415  C CD   . ARG   A 1 31  ? 38.23361 8.59842   18.46820 1.000 20.53569  ? 28  ARG   A CD   1 
ATOM   416  N NE   . ARG   A 1 31  ? 37.80827 8.83641   19.84264 1.000 20.37439  ? 28  ARG   A NE   1 
ATOM   417  C CZ   . ARG   A 1 31  ? 38.24564 9.82422   20.61364 1.000 26.51279  ? 28  ARG   A CZ   1 
ATOM   418  N NH1  . ARG   A 1 31  ? 39.14810 10.69294  20.18568 1.000 21.21069  ? 28  ARG   A NH1  1 
ATOM   419  N NH2  . ARG   A 1 31  ? 37.76830 9.93965   21.84939 1.000 25.57558  ? 28  ARG   A NH2  1 
ATOM   420  H H    . ARG   A 1 31  ? 35.89228 7.37770   15.42916 1.000 27.74681  ? 28  ARG   A H    1 
ATOM   421  H HA   . ARG   A 1 31  ? 36.18795 9.94371   15.19275 1.000 24.53227  ? 28  ARG   A HA   1 
ATOM   422  H HB2  . ARG   A 1 31  ? 38.01863 7.96302   15.97595 1.000 21.55567  ? 28  ARG   A HB2  1 
ATOM   423  H HB3  . ARG   A 1 31  ? 38.45883 9.48866   15.91226 1.000 21.55567  ? 28  ARG   A HB3  1 
ATOM   424  H HG2  . ARG   A 1 31  ? 37.04946 10.03028  17.61246 1.000 26.35164  ? 28  ARG   A HG2  1 
ATOM   425  H HG3  . ARG   A 1 31  ? 36.38835 8.58543   17.58527 1.000 26.35164  ? 28  ARG   A HG3  1 
ATOM   426  H HD2  . ARG   A 1 31  ? 38.36474 7.64421   18.35338 1.000 24.57720  ? 28  ARG   A HD2  1 
ATOM   427  H HD3  . ARG   A 1 31  ? 39.07032 9.06786   18.32522 1.000 24.57720  ? 28  ARG   A HD3  1 
ATOM   428  H HE   . ARG   A 1 31  ? 37.23026 8.29575   20.17907 1.000 24.38364  ? 28  ARG   A HE   1 
ATOM   429  H HH11 . ARG   A 1 31  ? 39.46627 10.62545  19.38956 1.000 25.38720  ? 28  ARG   A HH11 1 
ATOM   430  H HH12 . ARG   A 1 31  ? 39.41623 11.32484  20.70377 1.000 25.38720  ? 28  ARG   A HH12 1 
ATOM   431  H HH21 . ARG   A 1 31  ? 37.18435 9.37861   22.13894 1.000 30.62507  ? 28  ARG   A HH21 1 
ATOM   432  H HH22 . ARG   A 1 31  ? 38.04354 10.57533  22.35904 1.000 30.62507  ? 28  ARG   A HH22 1 
ATOM   433  N N    . ALA   A 1 32  ? 37.54564 8.28607   12.84517 1.000 21.72931  ? 29  ALA   A N    1 
ATOM   434  C CA   . ALA   A 1 32  ? 38.19421 8.35762   11.54416 1.000 21.60699  ? 29  ALA   A CA   1 
ATOM   435  C C    . ALA   A 1 32  ? 37.22759 8.72348   10.42477 1.000 23.45816  ? 29  ALA   A C    1 
ATOM   436  O O    . ALA   A 1 32  ? 37.61133 8.67806   9.25177  1.000 29.04694  ? 29  ALA   A O    1 
ATOM   437  C CB   . ALA   A 1 32  ? 38.87653 7.02396   11.22465 1.000 25.03681  ? 29  ALA   A CB   1 
ATOM   438  H H    . ALA   A 1 32  ? 37.29326 7.49184   13.05756 1.000 26.00954  ? 29  ALA   A H    1 
ATOM   439  H HA   . ALA   A 1 32  ? 38.87966 9.04307   11.57907 1.000 25.86276  ? 29  ALA   A HA   1 
ATOM   440  H HB1  . ALA   A 1 32  ? 39.30507 7.08841   10.35684 1.000 29.97855  ? 29  ALA   A HB1  1 
ATOM   441  H HB2  . ALA   A 1 32  ? 39.53925 6.83666   11.90774 1.000 29.97855  ? 29  ALA   A HB2  1 
ATOM   442  H HB3  . ALA   A 1 32  ? 38.20727 6.32194   11.21174 1.000 29.97855  ? 29  ALA   A HB3  1 
ATOM   443  N N    . GLY   A 1 33  ? 35.99093 9.08570   10.75654 1.000 25.19817  ? 30  GLY   A N    1 
ATOM   444  C CA   . GLY   A 1 33  ? 35.02045 9.46167   9.75114  1.000 32.35125  ? 30  GLY   A CA   1 
ATOM   445  C C    . GLY   A 1 33  ? 34.36813 8.30592   9.03143  1.000 28.22700  ? 30  GLY   A C    1 
ATOM   446  O O    . GLY   A 1 33  ? 33.68121 8.53035   8.02884  1.000 28.73176  ? 30  GLY   A O    1 
ATOM   447  H H    . GLY   A 1 33  ? 35.69396 9.12003   11.56290 1.000 30.17217  ? 30  GLY   A H    1 
ATOM   448  H HA2  . GLY   A 1 33  ? 34.31855 9.97921   10.17585 1.000 38.75588  ? 30  GLY   A HA2  1 
ATOM   449  H HA3  . GLY   A 1 33  ? 35.46097 10.01320  9.08582  1.000 38.75588  ? 30  GLY   A HA3  1 
ATOM   450  N N    . ILE   A 1 34  ? 34.56092 7.07982   9.50482  1.000 24.34507  ? 31  ILE   A N    1 
ATOM   451  C CA   . ILE   A 1 34  ? 33.94370 5.91048   8.89153  1.000 24.87098  ? 31  ILE   A CA   1 
ATOM   452  C C    . ILE   A 1 34  ? 32.50644 5.78826   9.37677  1.000 25.09940  ? 31  ILE   A C    1 
ATOM   453  O O    . ILE   A 1 34  ? 32.21309 5.99189   10.56104 1.000 26.43297  ? 31  ILE   A O    1 
ATOM   454  C CB   . ILE   A 1 34  ? 34.75249 4.64294   9.22229  1.000 23.46733  ? 31  ILE   A CB   1 
ATOM   455  C CG1  . ILE   A 1 34  ? 36.16207 4.74144   8.63219  1.000 26.02935  ? 31  ILE   A CG1  1 
ATOM   456  C CG2  . ILE   A 1 34  ? 34.03862 3.39999   8.70392  1.000 26.49938  ? 31  ILE   A CG2  1 
ATOM   457  C CD1  . ILE   A 1 34  ? 37.14038 3.73160   9.20219  1.000 26.74785  ? 31  ILE   A CD1  1 
ATOM   458  H H    . ILE   A 1 34  ? 35.05038 6.89674   10.18783 1.000 29.14845  ? 31  ILE   A H    1 
ATOM   459  H HA   . ILE   A 1 34  ? 33.93340 6.02457   7.92832  1.000 29.77955  ? 31  ILE   A HA   1 
ATOM   460  H HB   . ILE   A 1 34  ? 34.82682 4.57196   10.18683 1.000 28.09517  ? 31  ILE   A HB   1 
ATOM   461  H HG12 . ILE   A 1 34  ? 36.10962 4.59383   7.67493  1.000 31.16959  ? 31  ILE   A HG12 1 
ATOM   462  H HG13 . ILE   A 1 34  ? 36.51363 5.62732   8.81250  1.000 31.16959  ? 31  ILE   A HG13 1 
ATOM   463  H HG21 . ILE   A 1 34  ? 34.62215 2.63266   8.81166  1.000 31.73362  ? 31  ILE   A HG21 1 
ATOM   464  H HG22 . ILE   A 1 34  ? 33.22292 3.26920   9.21226  1.000 31.73362  ? 31  ILE   A HG22 1 
ATOM   465  H HG23 . ILE   A 1 34  ? 33.82710 3.52553   7.76562  1.000 31.73362  ? 31  ILE   A HG23 1 
ATOM   466  H HD11 . ILE   A 1 34  ? 38.03440 3.95043   8.89600  1.000 32.03179  ? 31  ILE   A HD11 1 
ATOM   467  H HD12 . ILE   A 1 34  ? 37.10413 3.76876   10.17080 1.000 32.03179  ? 31  ILE   A HD12 1 
ATOM   468  H HD13 . ILE   A 1 34  ? 36.89353 2.84502   8.89571  1.000 32.03179  ? 31  ILE   A HD13 1 
ATOM   469  N N    . LYS   A 1 35  ? 31.59982 5.45726   8.46021  1.000 25.53877  ? 32  LYS   A N    1 
ATOM   470  C CA   A LYS   A 1 35  ? 30.20152 5.22501   8.80919  0.331 29.07328  ? 32  LYS   A CA   1 
ATOM   471  C CA   B LYS   A 1 35  ? 30.20280 5.22681   8.81083  0.669 28.72756  ? 32  LYS   A CA   1 
ATOM   472  C C    . LYS   A 1 35  ? 30.06601 3.80126   9.33336  1.000 30.04577  ? 32  LYS   A C    1 
ATOM   473  O O    . LYS   A 1 35  ? 30.12956 2.83880   8.56103  1.000 27.92638  ? 32  LYS   A O    1 
ATOM   474  C CB   A LYS   A 1 35  ? 29.29209 5.45397   7.60479  0.331 36.86798  ? 32  LYS   A CB   1 
ATOM   475  C CB   B LYS   A 1 35  ? 29.30760 5.46838   7.59991  0.669 36.89190  ? 32  LYS   A CB   1 
ATOM   476  C CG   A LYS   A 1 35  ? 28.97545 6.92118   7.32600  0.331 39.15296  ? 32  LYS   A CG   1 
ATOM   477  C CG   B LYS   A 1 35  ? 27.82578 5.58492   7.92861  0.669 36.09044  ? 32  LYS   A CG   1 
ATOM   478  C CD   A LYS   A 1 35  ? 27.53633 7.11721   6.84755  0.331 59.90223  ? 32  LYS   A CD   1 
ATOM   479  C CD   B LYS   A 1 35  ? 26.97654 5.76677   6.67184  0.669 62.36225  ? 32  LYS   A CD   1 
ATOM   480  C CE   A LYS   A 1 35  ? 27.47077 7.51462   5.38114  0.331 71.07946  ? 32  LYS   A CE   1 
ATOM   481  C CE   B LYS   A 1 35  ? 27.45262 6.94240   5.82499  0.669 74.84572  ? 32  LYS   A CE   1 
ATOM   482  N NZ   A LYS   A 1 35  ? 26.06263 7.61119   4.90107  0.331 75.38932  ? 32  LYS   A NZ   1 
ATOM   483  N NZ   B LYS   A 1 35  ? 26.54461 7.23235   4.68095  0.669 80.98304  ? 32  LYS   A NZ   1 
ATOM   484  H H    A LYS   A 1 35  ? 31.77147 5.36038   7.62310  0.331 30.58090  ? 32  LYS   A H    1 
ATOM   485  H H    B LYS   A 1 35  ? 31.77112 5.35958   7.62312  0.669 30.58090  ? 32  LYS   A H    1 
ATOM   486  H HA   A LYS   A 1 35  ? 29.93633 5.84702   9.50466  0.331 34.82231  ? 32  LYS   A HA   1 
ATOM   487  H HA   B LYS   A 1 35  ? 29.93051 5.83974   9.51159  0.669 34.40744  ? 32  LYS   A HA   1 
ATOM   488  H HB2  A LYS   A 1 35  ? 29.72568 5.09205   6.81617  0.331 44.17595  ? 32  LYS   A HB2  1 
ATOM   489  H HB2  B LYS   A 1 35  ? 29.57991 6.29617   7.17387  0.669 44.20466  ? 32  LYS   A HB2  1 
ATOM   490  H HB3  A LYS   A 1 35  ? 28.45107 4.99640   7.76044  0.331 44.17595  ? 32  LYS   A HB3  1 
ATOM   491  H HB3  B LYS   A 1 35  ? 29.41425 4.72720   6.98333  0.669 44.20466  ? 32  LYS   A HB3  1 
ATOM   492  H HG2  A LYS   A 1 35  ? 29.09597 7.43405   8.14045  0.331 46.91793  ? 32  LYS   A HG2  1 
ATOM   493  H HG2  B LYS   A 1 35  ? 27.53326 4.77656   8.37793  0.669 43.24290  ? 32  LYS   A HG2  1 
ATOM   494  H HG3  A LYS   A 1 35  ? 29.57142 7.25065   6.63522  0.331 46.91793  ? 32  LYS   A HG3  1 
ATOM   495  H HG3  B LYS   A 1 35  ? 27.68513 6.35345   8.50348  0.669 43.24290  ? 32  LYS   A HG3  1 
ATOM   496  H HD2  A LYS   A 1 35  ? 27.04741 6.28675   6.95797  0.331 71.81705  ? 32  LYS   A HD2  1 
ATOM   497  H HD2  B LYS   A 1 35  ? 27.03005 4.96313   6.13128  0.669 74.76907  ? 32  LYS   A HD2  1 
ATOM   498  H HD3  A LYS   A 1 35  ? 27.11917 7.81982   7.37024  0.331 71.81705  ? 32  LYS   A HD3  1 
ATOM   499  H HD3  B LYS   A 1 35  ? 26.05622 5.93255   6.92960  0.669 74.76907  ? 32  LYS   A HD3  1 
ATOM   500  H HE2  A LYS   A 1 35  ? 27.89248 8.38030   5.26428  0.331 85.22972  ? 32  LYS   A HE2  1 
ATOM   501  H HE2  B LYS   A 1 35  ? 27.49673 7.73578   6.38133  0.669 89.74923  ? 32  LYS   A HE2  1 
ATOM   502  H HE3  A LYS   A 1 35  ? 27.92955 6.84731   4.84717  0.331 85.22972  ? 32  LYS   A HE3  1 
ATOM   503  H HE3  B LYS   A 1 35  ? 28.33083 6.73918   5.46673  0.669 89.74923  ? 32  LYS   A HE3  1 
ATOM   504  H HZ1  A LYS   A 1 35  ? 26.04714 7.89949   4.05920  0.331 90.40155  ? 32  LYS   A HZ1  1 
ATOM   505  H HZ1  B LYS   A 1 35  ? 26.86398 7.91221   4.20357  0.669 97.11402  ? 32  LYS   A HZ1  1 
ATOM   506  H HZ2  A LYS   A 1 35  ? 25.67229 6.81231   4.94002  0.331 90.40155  ? 32  LYS   A HZ2  1 
ATOM   507  H HZ2  B LYS   A 1 35  ? 26.47835 6.51674   4.15596  0.669 97.11402  ? 32  LYS   A HZ2  1 
ATOM   508  H HZ3  A LYS   A 1 35  ? 25.60594 8.18092   5.40993  0.331 90.40155  ? 32  LYS   A HZ3  1 
ATOM   509  H HZ3  B LYS   A 1 35  ? 25.73465 7.44592   4.98172  0.669 97.11402  ? 32  LYS   A HZ3  1 
ATOM   510  N N    . VAL   A 1 36  ? 29.88055 3.66363   10.64306 1.000 27.50651  ? 33  VAL   A N    1 
ATOM   511  C CA   . VAL   A 1 36  ? 29.83562 2.36412   11.30179 1.000 23.07116  ? 33  VAL   A CA   1 
ATOM   512  C C    . VAL   A 1 36  ? 28.39202 2.00698   11.61837 1.000 23.85103  ? 33  VAL   A C    1 
ATOM   513  O O    . VAL   A 1 36  ? 27.63956 2.83200   12.15189 1.000 25.74193  ? 33  VAL   A O    1 
ATOM   514  C CB   . VAL   A 1 36  ? 30.68554 2.36276   12.58395 1.000 26.34914  ? 33  VAL   A CB   1 
ATOM   515  C CG1  . VAL   A 1 36  ? 30.59343 1.00980   13.27437 1.000 22.37098  ? 33  VAL   A CG1  1 
ATOM   516  C CG2  . VAL   A 1 36  ? 32.12769 2.72041   12.26474 1.000 25.59085  ? 33  VAL   A CG2  1 
ATOM   517  H H    . VAL   A 1 36  ? 29.77590 4.32497   11.18276 1.000 32.94218  ? 33  VAL   A H    1 
ATOM   518  H HA   . VAL   A 1 36  ? 30.18361 1.69565   10.69109 1.000 27.61976  ? 33  VAL   A HA   1 
ATOM   519  H HB   . VAL   A 1 36  ? 30.34428 3.03358   13.19586 1.000 31.55334  ? 33  VAL   A HB   1 
ATOM   520  H HG11 . VAL   A 1 36  ? 31.29402 0.94780   13.94238 1.000 26.77954  ? 33  VAL   A HG11 1 
ATOM   521  H HG12 . VAL   A 1 36  ? 29.72448 0.92993   13.69797 1.000 26.77954  ? 33  VAL   A HG12 1 
ATOM   522  H HG13 . VAL   A 1 36  ? 30.70446 0.30934   12.61261 1.000 26.77954  ? 33  VAL   A HG13 1 
ATOM   523  H HG21 . VAL   A 1 36  ? 32.66205 2.62513   13.06865 1.000 30.64339  ? 33  VAL   A HG21 1 
ATOM   524  H HG22 . VAL   A 1 36  ? 32.45654 2.12167   11.57607 1.000 30.64339  ? 33  VAL   A HG22 1 
ATOM   525  H HG23 . VAL   A 1 36  ? 32.16351 3.63740   11.95050 1.000 30.64339  ? 33  VAL   A HG23 1 
ATOM   526  N N    . THR   A 1 37  ? 28.01176 0.77274   11.30351 1.000 25.00120  ? 34  THR   A N    1 
ATOM   527  C CA   . THR   A 1 37  ? 26.72099 0.21513   11.68078 1.000 28.29532  ? 34  THR   A CA   1 
ATOM   528  C C    . THR   A 1 37  ? 26.95775 -0.93822  12.64580 1.000 26.21372  ? 34  THR   A C    1 
ATOM   529  O O    . THR   A 1 37  ? 27.56711 -1.94734  12.27358 1.000 23.47406  ? 34  THR   A O    1 
ATOM   530  C CB   . THR   A 1 37  ? 25.94598 -0.26517  10.45382 1.000 25.99919  ? 34  THR   A CB   1 
ATOM   531  O OG1  . THR   A 1 37  ? 25.69045 0.84389   9.58392  1.000 29.68364  ? 34  THR   A OG1  1 
ATOM   532  C CG2  . THR   A 1 37  ? 24.62582 -0.90248  10.86886 1.000 28.39632  ? 34  THR   A CG2  1 
ATOM   533  H H    . THR   A 1 37  ? 28.50108 0.22370   10.85773 1.000 29.93581  ? 34  THR   A H    1 
ATOM   534  H HA   . THR   A 1 37  ? 26.19169 0.89490   12.12648 1.000 33.88876  ? 34  THR   A HA   1 
ATOM   535  H HB   . THR   A 1 37  ? 26.46836 -0.93170  9.98079  1.000 31.13340  ? 34  THR   A HB   1 
ATOM   536  H HG1  . THR   A 1 37  ? 25.39825 0.56884   8.84598  1.000 35.55474  ? 34  THR   A HG1  1 
ATOM   537  H HG21 . THR   A 1 37  ? 24.07717 -1.06865  10.08638 1.000 34.00996  ? 34  THR   A HG21 1 
ATOM   538  H HG22 . THR   A 1 37  ? 24.79160 -1.74416  11.32160 1.000 34.00996  ? 34  THR   A HG22 1 
ATOM   539  H HG23 . THR   A 1 37  ? 24.14628 -0.31094  11.46971 1.000 34.00996  ? 34  THR   A HG23 1 
ATOM   540  N N    . VAL   A 1 38  ? 26.48741 -0.78341  13.87927 1.000 19.95670  ? 35  VAL   A N    1 
ATOM   541  C CA   . VAL   A 1 38  ? 26.52217 -1.85505  14.86781 1.000 23.81620  ? 35  VAL   A CA   1 
ATOM   542  C C    . VAL   A 1 38  ? 25.22418 -2.63864  14.71370 1.000 23.13201  ? 35  VAL   A C    1 
ATOM   543  O O    . VAL   A 1 38  ? 24.14496 -2.14131  15.04424 1.000 26.17145  ? 35  VAL   A O    1 
ATOM   544  C CB   . VAL   A 1 38  ? 26.68737 -1.31134  16.29164 1.000 24.54085  ? 35  VAL   A CB   1 
ATOM   545  C CG1  . VAL   A 1 38  ? 26.69078 -2.45013  17.29693 1.000 28.40844  ? 35  VAL   A CG1  1 
ATOM   546  C CG2  . VAL   A 1 38  ? 27.96950 -0.49654  16.40475 1.000 24.71991  ? 35  VAL   A CG2  1 
ATOM   547  H H    . VAL   A 1 38  ? 26.13742 -0.05447  14.17210 1.000 23.88242  ? 35  VAL   A H    1 
ATOM   548  H HA   . VAL   A 1 38  ? 27.27164 -2.44444  14.68941 1.000 28.51382  ? 35  VAL   A HA   1 
ATOM   549  H HB   . VAL   A 1 38  ? 25.93855 -0.72903  16.49434 1.000 29.38339  ? 35  VAL   A HB   1 
ATOM   550  H HG11 . VAL   A 1 38  ? 26.95402 -2.10487  18.16434 1.000 34.02449  ? 35  VAL   A HG11 1 
ATOM   551  H HG12 . VAL   A 1 38  ? 25.79918 -2.82870  17.34829 1.000 34.02449  ? 35  VAL   A HG12 1 
ATOM   552  H HG13 . VAL   A 1 38  ? 27.32126 -3.12708  17.00514 1.000 34.02449  ? 35  VAL   A HG13 1 
ATOM   553  H HG21 . VAL   A 1 38  ? 28.04464 -0.14968  17.30749 1.000 29.59827  ? 35  VAL   A HG21 1 
ATOM   554  H HG22 . VAL   A 1 38  ? 28.72649 -1.06978  16.20658 1.000 29.59827  ? 35  VAL   A HG22 1 
ATOM   555  H HG23 . VAL   A 1 38  ? 27.93476 0.23657   15.77053 1.000 29.59827  ? 35  VAL   A HG23 1 
ATOM   556  N N    . ALA   A 1 39  ? 25.32675 -3.86076  14.20278 1.000 22.59967  ? 36  ALA   A N    1 
ATOM   557  C CA   . ALA   A 1 39  ? 24.16949 -4.66382  13.83745 1.000 21.70503  ? 36  ALA   A CA   1 
ATOM   558  C C    . ALA   A 1 39  ? 23.99907 -5.79693  14.83723 1.000 27.01659  ? 36  ALA   A C    1 
ATOM   559  O O    . ALA   A 1 39  ? 24.93152 -6.57408  15.06683 1.000 30.21737  ? 36  ALA   A O    1 
ATOM   560  C CB   . ALA   A 1 39  ? 24.32176 -5.21889  12.41996 1.000 29.19788  ? 36  ALA   A CB   1 
ATOM   561  H H    . ALA   A 1 39  ? 26.07676 -4.25490  14.05534 1.000 27.05398  ? 36  ALA   A H    1 
ATOM   562  H HA   . ALA   A 1 39  ? 23.36975 -4.11571  13.86706 1.000 25.98041  ? 36  ALA   A HA   1 
ATOM   563  H HB1  . ALA   A 1 39  ? 23.53692 -5.74512  12.20087 1.000 34.97183  ? 36  ALA   A HB1  1 
ATOM   564  H HB2  . ALA   A 1 39  ? 24.40792 -4.47900  11.79864 1.000 34.97183  ? 36  ALA   A HB2  1 
ATOM   565  H HB3  . ALA   A 1 39  ? 25.11474 -5.77628  12.38257 1.000 34.97183  ? 36  ALA   A HB3  1 
ATOM   566  N N    . GLY   A 1 40  ? 22.80948 -5.88430  15.43021 1.000 24.93027  ? 37  GLY   A N    1 
ATOM   567  C CA   . GLY   A 1 40  ? 22.50837 -6.97145  16.34600 1.000 26.29286  ? 37  GLY   A CA   1 
ATOM   568  C C    . GLY   A 1 40  ? 22.20621 -8.25102  15.58810 1.000 30.03895  ? 37  GLY   A C    1 
ATOM   569  O O    . GLY   A 1 40  ? 21.36674 -8.26963  14.68138 1.000 30.88576  ? 37  GLY   A O    1 
ATOM   570  H H    . GLY   A 1 40  ? 22.16437 -5.32696  15.31703 1.000 29.85070  ? 37  GLY   A H    1 
ATOM   571  H HA2  . GLY   A 1 40  ? 23.26728 -7.12704  16.92973 1.000 31.48581  ? 37  GLY   A HA2  1 
ATOM   572  H HA3  . GLY   A 1 40  ? 21.73672 -6.73981  16.88618 1.000 31.48581  ? 37  GLY   A HA3  1 
ATOM   573  N N    . LEU   A 1 41  ? 22.89877 -9.32839  15.96111 1.000 29.26654  ? 38  LEU   A N    1 
ATOM   574  C CA   . LEU   A 1 41  ? 22.68989 -10.61218 15.30098 1.000 35.60590  ? 38  LEU   A CA   1 
ATOM   575  C C    . LEU   A 1 41  ? 21.24543 -11.07615 15.43767 1.000 40.99301  ? 38  LEU   A C    1 
ATOM   576  O O    . LEU   A 1 41  ? 20.64722 -11.56171 14.47053 1.000 34.98599  ? 38  LEU   A O    1 
ATOM   577  C CB   . LEU   A 1 41  ? 23.64539 -11.65139 15.88792 1.000 32.20615  ? 38  LEU   A CB   1 
ATOM   578  C CG   . LEU   A 1 41  ? 23.58667 -13.07005 15.32059 1.000 36.09642  ? 38  LEU   A CG   1 
ATOM   579  C CD1  . LEU   A 1 41  ? 24.00228 -13.08616 13.86103 1.000 41.07119  ? 38  LEU   A CD1  1 
ATOM   580  C CD2  . LEU   A 1 41  ? 24.46865 -13.99918 16.13976 1.000 36.57296  ? 38  LEU   A CD2  1 
ATOM   581  H H    . LEU   A 1 41  ? 23.48864 -9.34120  16.58680 1.000 35.05422  ? 38  LEU   A H    1 
ATOM   582  H HA   . LEU   A 1 41  ? 22.88318 -10.51752 14.35516 1.000 42.66145  ? 38  LEU   A HA   1 
ATOM   583  H HB2  . LEU   A 1 41  ? 24.55086 -11.33196 15.75008 1.000 38.58176  ? 38  LEU   A HB2  1 
ATOM   584  H HB3  . LEU   A 1 41  ? 23.45927 -11.72156 16.83731 1.000 38.58176  ? 38  LEU   A HB3  1 
ATOM   585  H HG   . LEU   A 1 41  ? 22.67333 -13.39298 15.36989 1.000 43.25007  ? 38  LEU   A HG   1 
ATOM   586  H HD11 . LEU   A 1 41  ? 23.32468 -12.63368 13.33472 1.000 49.21980  ? 38  LEU   A HD11 1 
ATOM   587  H HD12 . LEU   A 1 41  ? 24.85251 -12.62826 13.76971 1.000 49.21980  ? 38  LEU   A HD12 1 
ATOM   588  H HD13 . LEU   A 1 41  ? 24.08911 -14.00661 13.56754 1.000 49.21980  ? 38  LEU   A HD13 1 
ATOM   589  H HD21 . LEU   A 1 41  ? 24.41012 -14.89516 15.77274 1.000 43.82192  ? 38  LEU   A HD21 1 
ATOM   590  H HD22 . LEU   A 1 41  ? 25.38489 -13.68359 16.09743 1.000 43.82192  ? 38  LEU   A HD22 1 
ATOM   591  H HD23 . LEU   A 1 41  ? 24.16044 -13.99770 17.05949 1.000 43.82192  ? 38  LEU   A HD23 1 
ATOM   592  N N    . ALA   A 1 42  ? 20.66653 -10.92789 16.62666 1.000 33.80153  ? 39  ALA   A N    1 
ATOM   593  C CA   . ALA   A 1 42  ? 19.33421 -11.43791 16.91660 1.000 41.45849  ? 39  ALA   A CA   1 
ATOM   594  C C    . ALA   A 1 42  ? 18.22891 -10.42577 16.64828 1.000 38.94954  ? 39  ALA   A C    1 
ATOM   595  O O    . ALA   A 1 42  ? 17.05166 -10.76426 16.80808 1.000 49.22363  ? 39  ALA   A O    1 
ATOM   596  C CB   . ALA   A 1 42  ? 19.25863 -11.89547 18.37638 1.000 39.97138  ? 39  ALA   A CB   1 
ATOM   597  H H    . ALA   A 1 42  ? 21.03437 -10.52740 17.29292 1.000 40.49620  ? 39  ALA   A H    1 
ATOM   598  H HA   . ALA   A 1 42  ? 19.17153 -12.20574 16.34663 1.000 49.68456  ? 39  ALA   A HA   1 
ATOM   599  H HB1  . ALA   A 1 42  ? 18.36795 -12.23558 18.55502 1.000 47.90003  ? 39  ALA   A HB1  1 
ATOM   600  H HB2  . ALA   A 1 42  ? 19.91511 -12.59443 18.52264 1.000 47.90003  ? 39  ALA   A HB2  1 
ATOM   601  H HB3  . ALA   A 1 42  ? 19.44609 -11.13941 18.95442 1.000 47.90003  ? 39  ALA   A HB3  1 
ATOM   602  N N    . GLY   A 1 43  ? 18.56853 -9.20795  16.25132 1.000 40.35377  ? 40  GLY   A N    1 
ATOM   603  C CA   . GLY   A 1 43  ? 17.59005 -8.18496  15.97053 1.000 33.14408  ? 40  GLY   A CA   1 
ATOM   604  C C    . GLY   A 1 43  ? 18.03357 -6.84897  16.52373 1.000 33.29890  ? 40  GLY   A C    1 
ATOM   605  O O    . GLY   A 1 43  ? 19.19296 -6.65111  16.88418 1.000 37.56595  ? 40  GLY   A O    1 
ATOM   606  H H    . GLY   A 1 43  ? 19.38084 -8.94999  16.13638 1.000 48.35890  ? 40  GLY   A H    1 
ATOM   607  H HA2  . GLY   A 1 43  ? 17.47009 -8.10080  15.01166 1.000 39.70727  ? 40  GLY   A HA2  1 
ATOM   608  H HA3  . GLY   A 1 43  ? 16.74140 -8.42352  16.37523 1.000 39.70727  ? 40  GLY   A HA3  1 
ATOM   609  N N    . LYS   A 1 44  ? 17.07755 -5.92301  16.58727 1.000 40.58827  ? 41  LYS   A N    1 
ATOM   610  C CA   . LYS   A 1 44  ? 17.31272 -4.55722  17.04036 1.000 41.94342  ? 41  LYS   A CA   1 
ATOM   611  C C    . LYS   A 1 44  ? 17.42552 -4.44400  18.55760 1.000 40.69442  ? 41  LYS   A C    1 
ATOM   612  O O    . LYS   A 1 44  ? 17.84533 -3.39413  19.05627 1.000 40.88634  ? 41  LYS   A O    1 
ATOM   613  C CB   . LYS   A 1 44  ? 16.17165 -3.66951  16.51729 1.000 46.27660  ? 41  LYS   A CB   1 
ATOM   614  C CG   . LYS   A 1 44  ? 16.22640 -2.18508  16.87726 1.000 98.84633  ? 41  LYS   A CG   1 
ATOM   615  C CD   . LYS   A 1 44  ? 16.95590 -1.35864  15.82827 1.000 79.24758  ? 41  LYS   A CD   1 
ATOM   616  C CE   . LYS   A 1 44  ? 16.57166 0.11214   15.92705 1.000 81.48171  ? 41  LYS   A CE   1 
ATOM   617  N NZ   . LYS   A 1 44  ? 15.12180 0.33271   15.64933 1.000 110.43938 ? 41  LYS   A NZ   1 
ATOM   618  H H    . LYS   A 1 44  ? 16.25904 -6.06702  16.36614 1.000 48.64030  ? 41  LYS   A H    1 
ATOM   619  H HA   . LYS   A 1 44  ? 18.14918 -4.22669  16.67705 1.000 50.26648  ? 41  LYS   A HA   1 
ATOM   620  H HB2  . LYS   A 1 44  ? 16.16930 -3.72510  15.54889 1.000 55.46630  ? 41  LYS   A HB2  1 
ATOM   621  H HB3  . LYS   A 1 44  ? 15.33739 -4.01514  16.87147 1.000 55.46630  ? 41  LYS   A HB3  1 
ATOM   622  H HG2  . LYS   A 1 44  ? 15.32185 -1.84327  16.95374 1.000 118.54996 ? 41  LYS   A HG2  1 
ATOM   623  H HG3  . LYS   A 1 44  ? 16.69324 -2.07991  17.72100 1.000 118.54996 ? 41  LYS   A HG3  1 
ATOM   624  H HD2  . LYS   A 1 44  ? 17.91317 -1.43554  15.96467 1.000 95.03146  ? 41  LYS   A HD2  1 
ATOM   625  H HD3  . LYS   A 1 44  ? 16.72010 -1.67864  14.94345 1.000 95.03146  ? 41  LYS   A HD3  1 
ATOM   626  H HE2  . LYS   A 1 44  ? 16.76016 0.43156   16.82334 1.000 97.71243  ? 41  LYS   A HE2  1 
ATOM   627  H HE3  . LYS   A 1 44  ? 17.08462 0.62004   15.27912 1.000 97.71243  ? 41  LYS   A HE3  1 
ATOM   628  H HZ1  . LYS   A 1 44  ? 14.89659 -0.05544  14.88074 1.000 132.46163 ? 41  LYS   A HZ1  1 
ATOM   629  H HZ2  . LYS   A 1 44  ? 14.62997 -0.01600  16.30401 1.000 132.46163 ? 41  LYS   A HZ2  1 
ATOM   630  H HZ3  . LYS   A 1 44  ? 14.95179 1.20453   15.59332 1.000 132.46163 ? 41  LYS   A HZ3  1 
ATOM   631  N N    . ASP   A 1 45  ? 17.09548 -5.49622  19.30069 1.000 37.50650  ? 42  ASP   A N    1 
ATOM   632  C CA   . ASP   A 1 45  ? 16.97401 -5.38069  20.74411 1.000 34.91547  ? 42  ASP   A CA   1 
ATOM   633  C C    . ASP   A 1 45  ? 18.34277 -5.23078  21.40655 1.000 37.45803  ? 42  ASP   A C    1 
ATOM   634  O O    . ASP   A 1 45  ? 19.36993 -5.59950  20.83259 1.000 27.59882  ? 42  ASP   A O    1 
ATOM   635  C CB   . ASP   A 1 45  ? 16.24900 -6.59882  21.30902 1.000 49.84797  ? 42  ASP   A CB   1 
ATOM   636  C CG   . ASP   A 1 45  ? 14.82159 -6.70994  20.80850 1.000 62.24009  ? 42  ASP   A CG   1 
ATOM   637  O OD1  . ASP   A 1 45  ? 14.13456 -5.66909  20.72929 1.000 54.25010  ? 42  ASP   A OD1  1 
ATOM   638  O OD2  . ASP   A 1 45  ? 14.38824 -7.83676  20.48921 1.000 73.01713  ? 42  ASP   A OD2  1 
ATOM   639  H H    . ASP   A 1 45  ? 16.93796 -6.28340  18.99225 1.000 44.94217  ? 42  ASP   A H    1 
ATOM   640  H HA   . ASP   A 1 45  ? 16.45823 -4.58710  20.95643 1.000 41.83294  ? 42  ASP   A HA   1 
ATOM   641  H HB2  . ASP   A 1 45  ? 16.72420 -7.40172  21.04362 1.000 59.75194  ? 42  ASP   A HB2  1 
ATOM   642  H HB3  . ASP   A 1 45  ? 16.22425 -6.53244  22.27643 1.000 59.75194  ? 42  ASP   A HB3  1 
ATOM   643  N N    . PRO   A 1 46  ? 18.37778 -4.69016  22.62596 1.000 35.04340  ? 43  PRO   A N    1 
ATOM   644  C CA   . PRO   A 1 46  ? 19.66327 -4.49002  23.30547 1.000 32.39809  ? 43  PRO   A CA   1 
ATOM   645  C C    . PRO   A 1 46  ? 20.38001 -5.81057  23.54083 1.000 30.84179  ? 43  PRO   A C    1 
ATOM   646  O O    . PRO   A 1 46  ? 19.75803 -6.85277  23.75771 1.000 27.82603  ? 43  PRO   A O    1 
ATOM   647  C CB   . PRO   A 1 46  ? 19.26902 -3.82047  24.62915 1.000 29.10250  ? 43  PRO   A CB   1 
ATOM   648  C CG   . PRO   A 1 46  ? 17.89658 -3.27417  24.39778 1.000 35.21916  ? 43  PRO   A CG   1 
ATOM   649  C CD   . PRO   A 1 46  ? 17.24640 -4.22288  23.44395 1.000 35.01831  ? 43  PRO   A CD   1 
ATOM   650  H HA   . PRO   A 1 46  ? 20.23407 -3.89496  22.79461 1.000 38.81208  ? 43  PRO   A HA   1 
ATOM   651  H HB2  . PRO   A 1 46  ? 19.26460 -4.47788  25.34238 1.000 34.85737  ? 43  PRO   A HB2  1 
ATOM   652  H HB3  . PRO   A 1 46  ? 19.89456 -3.10903  24.83760 1.000 34.85737  ? 43  PRO   A HB3  1 
ATOM   653  H HG2  . PRO   A 1 46  ? 17.41031 -3.24063  25.23641 1.000 42.19736  ? 43  PRO   A HG2  1 
ATOM   654  H HG3  . PRO   A 1 46  ? 17.95682 -2.38560  24.01344 1.000 42.19736  ? 43  PRO   A HG3  1 
ATOM   655  H HD2  . PRO   A 1 46  ? 16.83198 -4.96126  23.91719 1.000 41.95634  ? 43  PRO   A HD2  1 
ATOM   656  H HD3  . PRO   A 1 46  ? 16.58726 -3.76773  22.89689 1.000 41.95634  ? 43  PRO   A HD3  1 
ATOM   657  N N    . VAL   A 1 47  ? 21.70861 -5.75115  23.50688 1.000 26.13021  ? 44  VAL   A N    1 
ATOM   658  C CA   . VAL   A 1 47  ? 22.56111 -6.93291  23.56234 1.000 23.79722  ? 44  VAL   A CA   1 
ATOM   659  C C    . VAL   A 1 47  ? 23.35111 -6.90075  24.86250 1.000 23.82215  ? 44  VAL   A C    1 
ATOM   660  O O    . VAL   A 1 47  ? 24.07190 -5.93302  25.13733 1.000 23.21411  ? 44  VAL   A O    1 
ATOM   661  C CB   . VAL   A 1 47  ? 23.50267 -7.00182  22.34985 1.000 28.54663  ? 44  VAL   A CB   1 
ATOM   662  C CG1  . VAL   A 1 47  ? 24.45101 -8.18143  22.48061 1.000 25.10949  ? 44  VAL   A CG1  1 
ATOM   663  C CG2  . VAL   A 1 47  ? 22.69945 -7.09152  21.06265 1.000 29.80005  ? 44  VAL   A CG2  1 
ATOM   664  H H    . VAL   A 1 47  ? 22.15059 -5.01559  23.45026 1.000 31.29062  ? 44  VAL   A H    1 
ATOM   665  H HA   . VAL   A 1 47  ? 22.00215 -7.72562  23.57122 1.000 28.49104  ? 44  VAL   A HA   1 
ATOM   666  H HB   . VAL   A 1 47  ? 24.03630 -6.19253  22.31546 1.000 34.19033  ? 44  VAL   A HB   1 
ATOM   667  H HG11 . VAL   A 1 47  ? 24.82039 -8.38793  21.60778 1.000 30.06576  ? 44  VAL   A HG11 1 
ATOM   668  H HG12 . VAL   A 1 47  ? 25.16435 -7.94660  23.09454 1.000 30.06576  ? 44  VAL   A HG12 1 
ATOM   669  H HG13 . VAL   A 1 47  ? 23.95971 -8.94538  22.82104 1.000 30.06576  ? 44  VAL   A HG13 1 
ATOM   670  H HG21 . VAL   A 1 47  ? 23.30927 -7.20780  20.31733 1.000 35.69443  ? 44  VAL   A HG21 1 
ATOM   671  H HG22 . VAL   A 1 47  ? 22.09701 -7.84971  21.11852 1.000 35.69443  ? 44  VAL   A HG22 1 
ATOM   672  H HG23 . VAL   A 1 47  ? 22.19139 -6.27297  20.94975 1.000 35.69443  ? 44  VAL   A HG23 1 
ATOM   673  N N    . GLN   A 1 48  ? 23.22520 -7.96125  25.65632 1.000 24.48594  ? 45  GLN   A N    1 
ATOM   674  C CA   . GLN   A 1 48  ? 23.98770 -8.10450  26.88903 1.000 25.17296  ? 45  GLN   A CA   1 
ATOM   675  C C    . GLN   A 1 48  ? 25.34866 -8.71125  26.56028 1.000 28.74293  ? 45  GLN   A C    1 
ATOM   676  O O    . GLN   A 1 48  ? 25.43078 -9.85797  26.10920 1.000 26.23134  ? 45  GLN   A O    1 
ATOM   677  C CB   . GLN   A 1 48  ? 23.23092 -8.97260  27.89197 1.000 30.78433  ? 45  GLN   A CB   1 
ATOM   678  C CG   . GLN   A 1 48  ? 23.97580 -9.19690  29.19559 1.000 40.41011  ? 45  GLN   A CG   1 
ATOM   679  C CD   . GLN   A 1 48  ? 23.17975 -10.02050 30.18502 1.000 51.83450  ? 45  GLN   A CD   1 
ATOM   680  O OE1  . GLN   A 1 48  ? 22.53982 -11.00575 29.81697 1.000 51.21315  ? 45  GLN   A OE1  1 
ATOM   681  N NE2  . GLN   A 1 48  ? 23.20899 -9.61587  31.44989 1.000 73.05185  ? 45  GLN   A NE2  1 
ATOM   682  H H    . GLN   A 1 48  ? 22.69583 -8.62034  25.49831 1.000 29.31750  ? 45  GLN   A H    1 
ATOM   683  H HA   . GLN   A 1 48  ? 24.12769 -7.23344  27.29221 1.000 30.14192  ? 45  GLN   A HA   1 
ATOM   684  H HB2  . GLN   A 1 48  ? 22.38820 -8.54130  28.10344 1.000 36.87557  ? 45  GLN   A HB2  1 
ATOM   685  H HB3  . GLN   A 1 48  ? 23.06790 -9.84088  27.49146 1.000 36.87557  ? 45  GLN   A HB3  1 
ATOM   686  H HG2  . GLN   A 1 48  ? 24.80391 -9.66689  29.01053 1.000 48.42651  ? 45  GLN   A HG2  1 
ATOM   687  H HG3  . GLN   A 1 48  ? 24.16602 -8.33774  29.60371 1.000 48.42651  ? 45  GLN   A HG3  1 
ATOM   688  H HE21 . GLN   A 1 48  ? 23.66404 -8.91954  31.66819 1.000 87.59659  ? 45  GLN   A HE21 1 
ATOM   689  H HE22 . GLN   A 1 48  ? 22.77288 -10.05023 32.05050 1.000 87.59659  ? 45  GLN   A HE22 1 
ATOM   690  N N    . CYS   A 1 49  ? 26.41112 -7.94582  26.78914 1.000 28.14276  ? 46  CYS   A N    1 
ATOM   691  C CA   . CYS   A 1 49  ? 27.75499 -8.39064  26.45667 1.000 25.75915  ? 46  CYS   A CA   1 
ATOM   692  C C    . CYS   A 1 49  ? 28.33154 -9.24113  27.59016 1.000 21.12301  ? 46  CYS   A C    1 
ATOM   693  O O    . CYS   A 1 49  ? 27.69437 -9.47017  28.62266 1.000 22.82610  ? 46  CYS   A O    1 
ATOM   694  C CB   . CYS   A 1 49  ? 28.63646 -7.18549  26.14071 1.000 21.52344  ? 46  CYS   A CB   1 
ATOM   695  S SG   . CYS   A 1 49  ? 28.09574 -6.27023  24.67561 1.000 24.73041  ? 46  CYS   A SG   1 
ATOM   696  H H    . CYS   A 1 49  ? 26.37758 -7.16056  27.13819 1.000 33.70569  ? 46  CYS   A H    1 
ATOM   697  H HA   . CYS   A 1 49  ? 27.71814 -8.95028  25.66525 1.000 30.84535  ? 46  CYS   A HA   1 
ATOM   698  H HB2  . CYS   A 1 49  ? 28.61878 -6.57718  26.89605 1.000 25.76250  ? 46  CYS   A HB2  1 
ATOM   699  H HB3  . CYS   A 1 49  ? 29.54300 -7.49251  25.98314 1.000 25.76250  ? 46  CYS   A HB3  1 
ATOM   700  H HG   . CYS   A 1 49  ? 28.87568 -5.38450  24.45839 1.000 29.61086  ? 46  CYS   A HG   1 
ATOM   701  N N    . SER   A 1 50  ? 29.56709 -9.71201  27.39051 1.000 23.67840  ? 47  SER   A N    1 
ATOM   702  C CA   . SER   A 1 50  ? 30.11569 -10.76189 28.24606 1.000 24.61977  ? 47  SER   A CA   1 
ATOM   703  C C    . SER   A 1 50  ? 30.22138 -10.31401 29.69875 1.000 20.13990  ? 47  SER   A C    1 
ATOM   704  O O    . SER   A 1 50  ? 30.01102 -11.11604 30.61635 1.000 21.29750  ? 47  SER   A O    1 
ATOM   705  C CB   . SER   A 1 50  ? 31.48429 -11.20032 27.72232 1.000 22.57653  ? 47  SER   A CB   1 
ATOM   706  O OG   . SER   A 1 50  ? 32.44906 -10.17182 27.87078 1.000 24.11824  ? 47  SER   A OG   1 
ATOM   707  H H    . SER   A 1 50  ? 30.10117 -9.44230  26.77277 1.000 28.34845  ? 47  SER   A H    1 
ATOM   708  H HA   . SER   A 1 50  ? 29.51655 -11.52416 28.21623 1.000 29.47809  ? 47  SER   A HA   1 
ATOM   709  H HB2  . SER   A 1 50  ? 31.77649 -11.97872 28.22193 1.000 27.02621  ? 47  SER   A HB2  1 
ATOM   710  H HB3  . SER   A 1 50  ? 31.40378 -11.42116 26.78123 1.000 27.02621  ? 47  SER   A HB3  1 
ATOM   711  H HG   . SER   A 1 50  ? 32.23961 -9.51082  27.39663 1.000 28.87626  ? 47  SER   A HG   1 
ATOM   712  N N    . ARG   A 1 51  ? 30.56162 -9.04547  29.93288 1.000 23.12582  ? 48  ARG   A N    1 
ATOM   713  C CA   . ARG   A 1 51  ? 30.65167 -8.50173  31.28328 1.000 21.36047  ? 48  ARG   A CA   1 
ATOM   714  C C    . ARG   A 1 51  ? 29.43919 -7.64432  31.63437 1.000 22.88442  ? 48  ARG   A C    1 
ATOM   715  O O    . ARG   A 1 51  ? 29.55097 -6.68707  32.40797 1.000 23.20157  ? 48  ARG   A O    1 
ATOM   716  C CB   . ARG   A 1 51  ? 31.95084 -7.71281  31.45615 1.000 22.47833  ? 48  ARG   A CB   1 
ATOM   717  C CG   . ARG   A 1 51  ? 33.14806 -8.58253  31.85049 1.000 27.40691  ? 48  ARG   A CG   1 
ATOM   718  C CD   . ARG   A 1 51  ? 33.56607 -9.51697  30.72513 1.000 23.82696  ? 48  ARG   A CD   1 
ATOM   719  N NE   . ARG   A 1 51  ? 34.52258 -10.53214 31.15116 1.000 21.47018  ? 48  ARG   A NE   1 
ATOM   720  C CZ   . ARG   A 1 51  ? 34.97031 -11.50664 30.37024 1.000 25.91653  ? 48  ARG   A CZ   1 
ATOM   721  N NH1  . ARG   A 1 51  ? 34.57898 -11.61793 29.11098 1.000 24.64264  ? 48  ARG   A NH1  1 
ATOM   722  N NH2  . ARG   A 1 51  ? 35.83090 -12.39220 30.86436 1.000 29.88236  ? 48  ARG   A NH2  1 
ATOM   723  H H    . ARG   A 1 51  ? 30.74669 -8.47563  29.31592 1.000 27.68536  ? 48  ARG   A H    1 
ATOM   724  H HA   . ARG   A 1 51  ? 30.67772 -9.23824  31.91398 1.000 25.56694  ? 48  ARG   A HA   1 
ATOM   725  H HB2  . ARG   A 1 51  ? 32.16498 -7.27575  30.61709 1.000 26.90837  ? 48  ARG   A HB2  1 
ATOM   726  H HB3  . ARG   A 1 51  ? 31.82342 -7.04973  32.15256 1.000 26.90837  ? 48  ARG   A HB3  1 
ATOM   727  H HG2  . ARG   A 1 51  ? 33.90161 -8.01079  32.06540 1.000 32.82267  ? 48  ARG   A HG2  1 
ATOM   728  H HG3  . ARG   A 1 51  ? 32.91109 -9.12255  32.62063 1.000 32.82267  ? 48  ARG   A HG3  1 
ATOM   729  H HD2  . ARG   A 1 51  ? 32.77983 -9.97183  30.38479 1.000 28.52673  ? 48  ARG   A HD2  1 
ATOM   730  H HD3  . ARG   A 1 51  ? 33.97906 -8.99526  30.01933 1.000 28.52673  ? 48  ARG   A HD3  1 
ATOM   731  H HE   . ARG   A 1 51  ? 34.81468 -10.49682 31.95926 1.000 25.69859  ? 48  ARG   A HE   1 
ATOM   732  H HH11 . ARG   A 1 51  ? 34.02227 -11.05097 28.78199 1.000 29.50554  ? 48  ARG   A HH11 1 
ATOM   733  H HH12 . ARG   A 1 51  ? 34.88137 -12.25722 28.62162 1.000 29.50554  ? 48  ARG   A HH12 1 
ATOM   734  H HH21 . ARG   A 1 51  ? 36.09100 -12.32922 31.68166 1.000 35.79321  ? 48  ARG   A HH21 1 
ATOM   735  H HH22 . ARG   A 1 51  ? 36.12726 -13.02778 30.36655 1.000 35.79321  ? 48  ARG   A HH22 1 
ATOM   736  N N    . ASP   A 1 52  ? 28.27934 -7.97481  31.06639 1.000 21.06146  ? 49  ASP   A N    1 
ATOM   737  C CA   . ASP   A 1 52  ? 26.97219 -7.42907  31.41944 1.000 27.59858  ? 49  ASP   A CA   1 
ATOM   738  C C    . ASP   A 1 52  ? 26.78525 -5.97279  31.01551 1.000 28.01706  ? 49  ASP   A C    1 
ATOM   739  O O    . ASP   A 1 52  ? 25.79854 -5.34961  31.42761 1.000 26.37460  ? 49  ASP   A O    1 
ATOM   740  C CB   . ASP   A 1 52  ? 26.68800 -7.57895  32.91970 1.000 29.82693  ? 49  ASP   A CB   1 
ATOM   741  C CG   . ASP   A 1 52  ? 26.21053 -8.97274  33.28593 1.000 33.13231  ? 49  ASP   A CG   1 
ATOM   742  O OD1  . ASP   A 1 52  ? 25.93849 -9.77276  32.36521 1.000 31.82063  ? 49  ASP   A OD1  1 
ATOM   743  O OD2  . ASP   A 1 52  ? 26.10514 -9.26703  34.49465 1.000 43.19305  ? 49  ASP   A OD2  1 
ATOM   744  H H    . ASP   A 1 52  ? 28.22427 -8.55243  30.43163 1.000 25.20813  ? 49  ASP   A H    1 
ATOM   745  H HA   . ASP   A 1 52  ? 26.30884 -7.93760  30.92724 1.000 33.05267  ? 49  ASP   A HA   1 
ATOM   746  H HB2  . ASP   A 1 52  ? 27.50210 -7.39993  33.41579 1.000 35.72669  ? 49  ASP   A HB2  1 
ATOM   747  H HB3  . ASP   A 1 52  ? 25.99768 -6.94756  33.17601 1.000 35.72669  ? 49  ASP   A HB3  1 
ATOM   748  N N    . VAL   A 1 53  ? 27.69092 -5.40553  30.22086 1.000 24.47241  ? 50  VAL   A N    1 
ATOM   749  C CA   . VAL   A 1 53  ? 27.40402 -4.12998  29.57814 1.000 22.49724  ? 50  VAL   A CA   1 
ATOM   750  C C    . VAL   A 1 53  ? 26.35899 -4.36354  28.49641 1.000 24.76417  ? 50  VAL   A C    1 
ATOM   751  O O    . VAL   A 1 53  ? 26.47443 -5.29902  27.69384 1.000 24.50900  ? 50  VAL   A O    1 
ATOM   752  C CB   . VAL   A 1 53  ? 28.68372 -3.50892  29.00038 1.000 22.28460  ? 50  VAL   A CB   1 
ATOM   753  C CG1  . VAL   A 1 53  ? 28.35221 -2.24548  28.21409 1.000 22.26965  ? 50  VAL   A CG1  1 
ATOM   754  C CG2  . VAL   A 1 53  ? 29.67423 -3.20060  30.11518 1.000 26.61622  ? 50  VAL   A CG2  1 
ATOM   755  H H    . VAL   A 1 53  ? 28.46508 -5.73454  30.04187 1.000 29.30126  ? 50  VAL   A H    1 
ATOM   756  H HA   . VAL   A 1 53  ? 27.04845 -3.50833  30.23237 1.000 26.93106  ? 50  VAL   A HA   1 
ATOM   757  H HB   . VAL   A 1 53  ? 29.09710 -4.14383  28.39464 1.000 26.67589  ? 50  VAL   A HB   1 
ATOM   758  H HG11 . VAL   A 1 53  ? 29.16022 -1.71987  28.10564 1.000 26.65796  ? 50  VAL   A HG11 1 
ATOM   759  H HG12 . VAL   A 1 53  ? 28.00213 -2.49703  27.34514 1.000 26.65796  ? 50  VAL   A HG12 1 
ATOM   760  H HG13 . VAL   A 1 53  ? 27.68828 -1.73442  28.70287 1.000 26.65796  ? 50  VAL   A HG13 1 
ATOM   761  H HG21 . VAL   A 1 53  ? 30.46142 -2.78325  29.73171 1.000 31.87384  ? 50  VAL   A HG21 1 
ATOM   762  H HG22 . VAL   A 1 53  ? 29.25691 -2.59828  30.75076 1.000 31.87384  ? 50  VAL   A HG22 1 
ATOM   763  H HG23 . VAL   A 1 53  ? 29.92058 -4.02845  30.55663 1.000 31.87384  ? 50  VAL   A HG23 1 
ATOM   764  N N    . VAL   A 1 54  ? 25.32506 -3.52757  28.47863 1.000 23.85653  ? 51  VAL   A N    1 
ATOM   765  C CA   . VAL   A 1 54  ? 24.19724 -3.68507  27.56593 1.000 25.57056  ? 51  VAL   A CA   1 
ATOM   766  C C    . VAL   A 1 54  ? 24.26301 -2.56877  26.53272 1.000 21.79317  ? 51  VAL   A C    1 
ATOM   767  O O    . VAL   A 1 54  ? 24.19092 -1.38364  26.88004 1.000 25.36699  ? 51  VAL   A O    1 
ATOM   768  C CB   . VAL   A 1 54  ? 22.85661 -3.67399  28.31554 1.000 26.93517  ? 51  VAL   A CB   1 
ATOM   769  C CG1  . VAL   A 1 54  ? 21.70110 -3.75075  27.33204 1.000 25.52765  ? 51  VAL   A CG1  1 
ATOM   770  C CG2  . VAL   A 1 54  ? 22.79442 -4.83161  29.30425 1.000 26.66425  ? 51  VAL   A CG2  1 
ATOM   771  H H    . VAL   A 1 54  ? 25.25314 -2.84601  28.99815 1.000 28.56221  ? 51  VAL   A H    1 
ATOM   772  H HA   . VAL   A 1 54  ? 24.27861 -4.53174  27.09964 1.000 30.61905  ? 51  VAL   A HA   1 
ATOM   773  H HB   . VAL   A 1 54  ? 22.77808 -2.84462  28.81239 1.000 32.25658  ? 51  VAL   A HB   1 
ATOM   774  H HG11 . VAL   A 1 54  ? 20.88952 -3.97212  27.81498 1.000 30.56755  ? 51  VAL   A HG11 1 
ATOM   775  H HG12 . VAL   A 1 54  ? 21.60140 -2.89094  26.89422 1.000 30.56755  ? 51  VAL   A HG12 1 
ATOM   776  H HG13 . VAL   A 1 54  ? 21.89185 -4.43706  26.67364 1.000 30.56755  ? 51  VAL   A HG13 1 
ATOM   777  H HG21 . VAL   A 1 54  ? 21.92549 -4.83236  29.73537 1.000 31.93148  ? 51  VAL   A HG21 1 
ATOM   778  H HG22 . VAL   A 1 54  ? 22.92629 -5.66421  28.82437 1.000 31.93148  ? 51  VAL   A HG22 1 
ATOM   779  H HG23 . VAL   A 1 54  ? 23.49279 -4.71806  29.96778 1.000 31.93148  ? 51  VAL   A HG23 1 
ATOM   780  N N    . ILE   A 1 55  ? 24.38712 -2.94915  25.26333 1.000 20.56939  ? 52  ILE   A N    1 
ATOM   781  C CA   . ILE   A 1 55  ? 24.57651 -2.01417  24.16205 1.000 20.55718  ? 52  ILE   A CA   1 
ATOM   782  C C    . ILE   A 1 55  ? 23.37989 -2.11365  23.22763 1.000 27.19714  ? 52  ILE   A C    1 
ATOM   783  O O    . ILE   A 1 55  ? 22.93885 -3.21863  22.89095 1.000 26.46482  ? 52  ILE   A O    1 
ATOM   784  C CB   . ILE   A 1 55  ? 25.88868 -2.29965  23.40770 1.000 23.51510  ? 52  ILE   A CB   1 
ATOM   785  C CG1  . ILE   A 1 55  ? 27.08707 -1.96510  24.30084 1.000 25.46742  ? 52  ILE   A CG1  1 
ATOM   786  C CG2  . ILE   A 1 55  ? 25.93609 -1.52065  22.09969 1.000 24.33977  ? 52  ILE   A CG2  1 
ATOM   787  C CD1  . ILE   A 1 55  ? 28.41549 -2.42582  23.74372 1.000 24.72681  ? 52  ILE   A CD1  1 
ATOM   788  H H    . ILE   A 1 55  ? 24.36380 -3.77050  25.00947 1.000 24.61763  ? 52  ILE   A H    1 
ATOM   789  H HA   . ILE   A 1 55  ? 24.60871 -1.10921  24.50977 1.000 24.60299  ? 52  ILE   A HA   1 
ATOM   790  H HB   . ILE   A 1 55  ? 25.92607 -3.24395  23.18907 1.000 28.15250  ? 52  ILE   A HB   1 
ATOM   791  H HG12 . ILE   A 1 55  ? 27.13201 -1.00272  24.41361 1.000 30.49527  ? 52  ILE   A HG12 1 
ATOM   792  H HG13 . ILE   A 1 55  ? 26.96303 -2.39457  25.16170 1.000 30.49527  ? 52  ILE   A HG13 1 
ATOM   793  H HG21 . ILE   A 1 55  ? 26.84818 -1.51286  21.76965 1.000 29.14209  ? 52  ILE   A HG21 1 
ATOM   794  H HG22 . ILE   A 1 55  ? 25.35441 -1.95171  21.45414 1.000 29.14209  ? 52  ILE   A HG22 1 
ATOM   795  H HG23 . ILE   A 1 55  ? 25.63517 -0.61285  22.26169 1.000 29.14209  ? 52  ILE   A HG23 1 
ATOM   796  H HD11 . ILE   A 1 55  ? 29.08653 -2.37213  24.44209 1.000 29.60655  ? 52  ILE   A HD11 1 
ATOM   797  H HD12 . ILE   A 1 55  ? 28.32893 -3.34227  23.43791 1.000 29.60655  ? 52  ILE   A HD12 1 
ATOM   798  H HD13 . ILE   A 1 55  ? 28.66316 -1.85165  23.00217 1.000 29.60655  ? 52  ILE   A HD13 1 
ATOM   799  N N    . CYS   A 1 56  ? 22.85811 -0.95978  22.81164 1.000 26.19494  ? 53  CYS   A N    1 
ATOM   800  C CA   . CYS   A 1 56  ? 21.75974 -0.91691  21.85462 1.000 26.64201  ? 53  CYS   A CA   1 
ATOM   801  C C    . CYS   A 1 56  ? 22.31905 -0.86167  20.43934 1.000 28.51204  ? 53  CYS   A C    1 
ATOM   802  O O    . CYS   A 1 56  ? 22.99873 0.11452   20.09457 1.000 29.42568  ? 53  CYS   A O    1 
ATOM   803  C CB   . CYS   A 1 56  ? 20.87416 0.29168   22.10339 1.000 29.71712  ? 53  CYS   A CB   1 
ATOM   804  S SG   . CYS   A 1 56  ? 19.98305 0.25622   23.66721 1.000 43.72865  ? 53  CYS   A SG   1 
ATOM   805  H H    . CYS   A 1 56  ? 23.12581 -0.18498  23.07167 1.000 31.36830  ? 53  CYS   A H    1 
ATOM   806  H HA   . CYS   A 1 56  ? 21.21945 -1.71741  21.94512 1.000 31.90478  ? 53  CYS   A HA   1 
ATOM   807  H HB2  . CYS   A 1 56  ? 21.42941 1.08704   22.10063 1.000 35.59492  ? 53  CYS   A HB2  1 
ATOM   808  H HB3  . CYS   A 1 56  ? 20.21628 0.34389   21.39250 1.000 35.59492  ? 53  CYS   A HB3  1 
ATOM   809  H HG   . CYS   A 1 56  ? 19.28203 1.22747   23.73952 1.000 52.40875  ? 53  CYS   A HG   1 
ATOM   810  N N    . PRO   A 1 57  ? 22.06704 -1.86032  19.59554 1.000 31.11107  ? 54  PRO   A N    1 
ATOM   811  C CA   . PRO   A 1 57  ? 22.60223 -1.81840  18.23146 1.000 25.47472  ? 54  PRO   A CA   1 
ATOM   812  C C    . PRO   A 1 57  ? 21.90665 -0.76473  17.38337 1.000 25.45627  ? 54  PRO   A C    1 
ATOM   813  O O    . PRO   A 1 57  ? 20.79150 -0.32284  17.66934 1.000 25.43697  ? 54  PRO   A O    1 
ATOM   814  C CB   . PRO   A 1 57  ? 22.33495 -3.23061  17.69743 1.000 28.40996  ? 54  PRO   A CB   1 
ATOM   815  C CG   . PRO   A 1 57  ? 21.18294 -3.72579  18.49727 1.000 37.12937  ? 54  PRO   A CG   1 
ATOM   816  C CD   . PRO   A 1 57  ? 21.32454 -3.10739  19.85890 1.000 25.93264  ? 54  PRO   A CD   1 
ATOM   817  H HA   . PRO   A 1 57  ? 23.55705 -1.64773  18.24153 1.000 30.50404  ? 54  PRO   A HA   1 
ATOM   818  H HB2  . PRO   A 1 57  ? 22.11254 -3.19140  16.75409 1.000 34.02632  ? 54  PRO   A HB2  1 
ATOM   819  H HB3  . PRO   A 1 57  ? 23.11698 -3.78873  17.83098 1.000 34.02632  ? 54  PRO   A HB3  1 
ATOM   820  H HG2  . PRO   A 1 57  ? 20.35262 -3.44827  18.07961 1.000 44.48961  ? 54  PRO   A HG2  1 
ATOM   821  H HG3  . PRO   A 1 57  ? 21.21799 -4.69343  18.55513 1.000 44.48961  ? 54  PRO   A HG3  1 
ATOM   822  H HD2  . PRO   A 1 57  ? 20.45438 -2.91570  20.24228 1.000 31.05354  ? 54  PRO   A HD2  1 
ATOM   823  H HD3  . PRO   A 1 57  ? 21.82699 -3.68893  20.45071 1.000 31.05354  ? 54  PRO   A HD3  1 
ATOM   824  N N    . ASP   A 1 58  ? 22.60214 -0.35750  16.31862 1.000 26.57169  ? 55  ASP   A N    1 
ATOM   825  C CA   . ASP   A 1 58  ? 22.04110 0.62027   15.39289 1.000 27.71026  ? 55  ASP   A CA   1 
ATOM   826  C C    . ASP   A 1 58  ? 20.93010 0.01854   14.54410 1.000 30.11685  ? 55  ASP   A C    1 
ATOM   827  O O    . ASP   A 1 58  ? 20.01129 0.73297   14.12707 1.000 32.79796  ? 55  ASP   A O    1 
ATOM   828  C CB   . ASP   A 1 58  ? 23.14041 1.17544   14.48837 1.000 32.34153  ? 55  ASP   A CB   1 
ATOM   829  C CG   . ASP   A 1 58  ? 24.21922 1.90284   15.26188 1.000 29.71221  ? 55  ASP   A CG   1 
ATOM   830  O OD1  . ASP   A 1 58  ? 23.87826 2.65592   16.19786 1.000 31.84415  ? 55  ASP   A OD1  1 
ATOM   831  O OD2  . ASP   A 1 58  ? 25.40975 1.71708   14.93487 1.000 30.23380  ? 55  ASP   A OD2  1 
ATOM   832  H H    . ASP   A 1 58  ? 23.39168 -0.62999  16.11377 1.000 31.82040  ? 55  ASP   A H    1 
ATOM   833  H HA   . ASP   A 1 58  ? 21.66798 1.35319   15.90719 1.000 33.18669  ? 55  ASP   A HA   1 
ATOM   834  H HB2  . ASP   A 1 58  ? 23.55684 0.44187   14.00945 1.000 38.74421  ? 55  ASP   A HB2  1 
ATOM   835  H HB3  . ASP   A 1 58  ? 22.74739 1.80124   13.86003 1.000 38.74421  ? 55  ASP   A HB3  1 
ATOM   836  N N    . ALA   A 1 59  ? 20.99655 -1.28050  14.27626 1.000 29.01702  ? 56  ALA   A N    1 
ATOM   837  C CA   . ALA   A 1 59  ? 20.02021 -1.93650  13.42111 1.000 35.09375  ? 56  ALA   A CA   1 
ATOM   838  C C    . ALA   A 1 59  ? 20.11664 -3.43644  13.64631 1.000 34.08276  ? 56  ALA   A C    1 
ATOM   839  O O    . ALA   A 1 59  ? 21.06660 -3.93426  14.25416 1.000 31.08528  ? 56  ALA   A O    1 
ATOM   840  C CB   . ALA   A 1 59  ? 20.25198 -1.59262  11.94649 1.000 29.86325  ? 56  ALA   A CB   1 
ATOM   841  H H    A ALA   A 1 59  ? 21.60392 -1.80739  14.58137 0.670 34.75479  ? 56  ALA   A H    1 
ATOM   842  H H    B ALA   A 1 59  ? 21.60392 -1.80739  14.58137 0.330 34.75479  ? 56  ALA   A H    1 
ATOM   843  H HA   . ALA   A 1 59  ? 19.12942 -1.64349  13.66921 1.000 42.04687  ? 56  ALA   A HA   1 
ATOM   844  H HB1  . ALA   A 1 59  ? 19.57450 -2.03246  11.40939 1.000 35.77027  ? 56  ALA   A HB1  1 
ATOM   845  H HB2  . ALA   A 1 59  ? 20.19128 -0.63119  11.83311 1.000 35.77027  ? 56  ALA   A HB2  1 
ATOM   846  H HB3  . ALA   A 1 59  ? 21.13349 -1.90154  11.68495 1.000 35.77027  ? 56  ALA   A HB3  1 
ATOM   847  N N    . SER   A 1 60  ? 19.11021 -4.15182  13.15697 1.000 35.31053  ? 57  SER   A N    1 
ATOM   848  C CA   . SER   A 1 60  ? 19.20590 -5.59987  13.08754 1.000 36.92671  ? 57  SER   A CA   1 
ATOM   849  C C    . SER   A 1 60  ? 20.16004 -5.99194  11.96647 1.000 31.19088  ? 57  SER   A C    1 
ATOM   850  O O    . SER   A 1 60  ? 20.35849 -5.24910  11.00078 1.000 28.13802  ? 57  SER   A O    1 
ATOM   851  C CB   . SER   A 1 60  ? 17.83265 -6.22361  12.84493 1.000 38.46414  ? 57  SER   A CB   1 
ATOM   852  O OG   . SER   A 1 60  ? 17.40499 -6.00486  11.51218 1.000 37.15249  ? 57  SER   A OG   1 
ATOM   853  H H    . SER   A 1 60  ? 18.37109 -3.82508  12.86277 1.000 42.30701  ? 57  SER   A H    1 
ATOM   854  H HA   . SER   A 1 60  ? 19.54010 -5.94982  13.92823 1.000 44.24642  ? 57  SER   A HA   1 
ATOM   855  H HB2  . SER   A 1 60  ? 17.88726 -7.17862  13.00580 1.000 46.09134  ? 57  SER   A HB2  1 
ATOM   856  H HB3  . SER   A 1 60  ? 17.19186 -5.82106  13.45176 1.000 46.09134  ? 57  SER   A HB3  1 
ATOM   857  H HG   . SER   A 1 60  ? 16.68466 -6.41322  11.37091 1.000 44.51736  ? 57  SER   A HG   1 
ATOM   858  N N    . LEU   A 1 61  ? 20.76554 -7.17098  12.10404 1.000 30.89814  ? 58  LEU   A N    1 
ATOM   859  C CA   . LEU   A 1 61  ? 21.62838 -7.66460  11.03775 1.000 30.75416  ? 58  LEU   A CA   1 
ATOM   860  C C    . LEU   A 1 61  ? 20.84127 -7.84432  9.74572  1.000 32.73125  ? 58  LEU   A C    1 
ATOM   861  O O    . LEU   A 1 61  ? 21.36023 -7.59247  8.65175  1.000 32.58426  ? 58  LEU   A O    1 
ATOM   862  C CB   . LEU   A 1 61  ? 22.28460 -8.97891  11.45719 1.000 29.56911  ? 58  LEU   A CB   1 
ATOM   863  C CG   . LEU   A 1 61  ? 23.32281 -9.52610  10.47563 1.000 31.03620  ? 58  LEU   A CG   1 
ATOM   864  C CD1  . LEU   A 1 61  ? 24.43853 -8.51412  10.26375 1.000 32.07847  ? 58  LEU   A CD1  1 
ATOM   865  C CD2  . LEU   A 1 61  ? 23.87966 -10.84792 10.97227 1.000 33.09194  ? 58  LEU   A CD2  1 
ATOM   866  H H    . LEU   A 1 61  ? 20.69463 -7.68949  12.78648 1.000 37.01214  ? 58  LEU   A H    1 
ATOM   867  H HA   . LEU   A 1 61  ? 22.33492 -7.01969  10.87715 1.000 36.83936  ? 58  LEU   A HA   1 
ATOM   868  H HB2  . LEU   A 1 61  ? 22.73151 -8.84053  12.30691 1.000 35.41731  ? 58  LEU   A HB2  1 
ATOM   869  H HB3  . LEU   A 1 61  ? 21.59131 -9.65059  11.55249 1.000 35.41731  ? 58  LEU   A HB3  1 
ATOM   870  H HG   . LEU   A 1 61  ? 22.89752 -9.68576  9.61858  1.000 37.17781  ? 58  LEU   A HG   1 
ATOM   871  H HD11 . LEU   A 1 61  ? 25.19980 -8.96256  9.86342  1.000 38.42854  ? 58  LEU   A HD11 1 
ATOM   872  H HD12 . LEU   A 1 61  ? 24.12060 -7.81229  9.67447  1.000 38.42854  ? 58  LEU   A HD12 1 
ATOM   873  H HD13 . LEU   A 1 61  ? 24.69009 -8.13721  11.12140 1.000 38.42854  ? 58  LEU   A HD13 1 
ATOM   874  H HD21 . LEU   A 1 61  ? 24.50338 -11.19466 10.31526 1.000 39.64471  ? 58  LEU   A HD21 1 
ATOM   875  H HD22 . LEU   A 1 61  ? 24.33534 -10.70159 11.81598 1.000 39.64471  ? 58  LEU   A HD22 1 
ATOM   876  H HD23 . LEU   A 1 61  ? 23.14785 -11.47254 11.09555 1.000 39.64471  ? 58  LEU   A HD23 1 
ATOM   877  N N    . GLU   A 1 62  ? 19.58080 -8.27016  9.85447  1.000 39.20739  ? 59  GLU   A N    1 
ATOM   878  C CA   . GLU   A 1 62  ? 18.75276 -8.45700  8.66747  1.000 42.18802  ? 59  GLU   A CA   1 
ATOM   879  C C    . GLU   A 1 62  ? 18.62289 -7.15732  7.88205  1.000 33.52000  ? 59  GLU   A C    1 
ATOM   880  O O    . GLU   A 1 62  ? 18.79549 -7.13717  6.65815  1.000 42.33243  ? 59  GLU   A O    1 
ATOM   881  C CB   . GLU   A 1 62  ? 17.37545 -8.98142  9.07454  1.000 52.27249  ? 59  GLU   A CB   1 
ATOM   882  C CG   . GLU   A 1 62  ? 16.52757 -9.46879  7.91284  1.000 90.55224  ? 59  GLU   A CG   1 
ATOM   883  C CD   . GLU   A 1 62  ? 15.08678 -9.72398  8.31095  1.000 116.55750 ? 59  GLU   A CD   1 
ATOM   884  O OE1  . GLU   A 1 62  ? 14.79522 -9.73409  9.52608  1.000 79.15504  ? 59  GLU   A OE1  1 
ATOM   885  O OE2  . GLU   A 1 62  ? 14.24459 -9.90950  7.40735  1.000 114.29327 ? 59  GLU   A OE2  1 
ATOM   886  H H    . GLU   A 1 62  ? 19.18718 -8.45542  10.59632 1.000 46.98324  ? 59  GLU   A H    1 
ATOM   887  H HA   . GLU   A 1 62  ? 19.17040 -9.11622  8.09136  1.000 50.56000  ? 59  GLU   A HA   1 
ATOM   888  H HB2  . GLU   A 1 62  ? 17.49492 -9.72606  9.68457  1.000 62.66136  ? 59  GLU   A HB2  1 
ATOM   889  H HB3  . GLU   A 1 62  ? 16.88905 -8.26680  9.51458  1.000 62.66136  ? 59  GLU   A HB3  1 
ATOM   890  H HG2  . GLU   A 1 62  ? 16.53183 -8.79657  7.21354  1.000 108.59706 ? 59  GLU   A HG2  1 
ATOM   891  H HG3  . GLU   A 1 62  ? 16.89837 -10.29965 7.57659  1.000 108.59706 ? 59  GLU   A HG3  1 
ATOM   892  N N    . ASP   A 1 63  ? 18.31833 -6.05616  8.57352  1.000 36.69109  ? 60  ASP   A N    1 
ATOM   893  C CA   . ASP   A 1 63  ? 18.18901 -4.77138  7.89369  1.000 37.63837  ? 60  ASP   A CA   1 
ATOM   894  C C    . ASP   A 1 63  ? 19.53971 -4.26645  7.40020  1.000 43.20600  ? 60  ASP   A C    1 
ATOM   895  O O    . ASP   A 1 63  ? 19.63949 -3.73053  6.29038  1.000 44.43145  ? 60  ASP   A O    1 
ATOM   896  C CB   . ASP   A 1 63  ? 17.54356 -3.74618  8.82698  1.000 43.13931  ? 60  ASP   A CB   1 
ATOM   897  C CG   . ASP   A 1 63  ? 16.08733 -4.05702  9.11837  1.000 41.21333  ? 60  ASP   A CG   1 
ATOM   898  O OD1  . ASP   A 1 63  ? 15.41236 -4.62866  8.23697  1.000 50.72317  ? 60  ASP   A OD1  1 
ATOM   899  O OD2  . ASP   A 1 63  ? 15.61730 -3.72848  10.22794 1.000 54.98652  ? 60  ASP   A OD2  1 
ATOM   900  H H    A ASP   A 1 63  ? 18.18420 -6.02832  9.42254  0.611 43.96368  ? 60  ASP   A H    1 
ATOM   901  H H    B ASP   A 1 63  ? 18.18420 -6.02832  9.42254  0.389 43.96368  ? 60  ASP   A H    1 
ATOM   902  H HA   . ASP   A 1 63  ? 17.61058 -4.88464  7.12331  1.000 45.10042  ? 60  ASP   A HA   1 
ATOM   903  H HB2  . ASP   A 1 63  ? 18.02369 -3.73896  9.66978  1.000 51.70155  ? 60  ASP   A HB2  1 
ATOM   904  H HB3  . ASP   A 1 63  ? 17.58673 -2.87000  8.41305  1.000 51.70155  ? 60  ASP   A HB3  1 
ATOM   905  N N    . ALA   A 1 64  ? 20.59072 -4.42400  8.20910  1.000 41.20406  ? 61  ALA   A N    1 
ATOM   906  C CA   . ALA   A 1 64  ? 21.90941 -3.95176  7.79959  1.000 39.02916  ? 61  ALA   A CA   1 
ATOM   907  C C    . ALA   A 1 64  ? 22.42912 -4.71986  6.59203  1.000 36.14871  ? 61  ALA   A C    1 
ATOM   908  O O    . ALA   A 1 64  ? 23.15552 -4.15670  5.76533  1.000 39.29492  ? 61  ALA   A O    1 
ATOM   909  C CB   . ALA   A 1 64  ? 22.89355 -4.06780  8.96339  1.000 41.96050  ? 61  ALA   A CB   1 
ATOM   910  H H    . ALA   A 1 64  ? 20.56558 -4.79421  8.98494  1.000 49.37924  ? 61  ALA   A H    1 
ATOM   911  H HA   . ALA   A 1 64  ? 21.84278 -3.01548  7.55494  1.000 46.76937  ? 61  ALA   A HA   1 
ATOM   912  H HB1  . ALA   A 1 64  ? 23.76223 -3.74607  8.67566  1.000 50.28697  ? 61  ALA   A HB1  1 
ATOM   913  H HB2  . ALA   A 1 64  ? 22.57097 -3.53141  9.70442  1.000 50.28697  ? 61  ALA   A HB2  1 
ATOM   914  H HB3  . ALA   A 1 64  ? 22.95742 -4.99785  9.23141  1.000 50.28697  ? 61  ALA   A HB3  1 
ATOM   915  N N    . LYS   A 1 65  ? 22.07379 -6.00143  6.47918  1.000 40.08057  ? 62  LYS   A N    1 
ATOM   916  C CA   . LYS   A 1 65  ? 22.48251 -6.79741  5.32602  1.000 45.80647  ? 62  LYS   A CA   1 
ATOM   917  C C    . LYS   A 1 65  ? 22.06091 -6.13625  4.01925  1.000 49.73292  ? 62  LYS   A C    1 
ATOM   918  O O    . LYS   A 1 65  ? 22.80279 -6.16444  3.03033  1.000 53.38353  ? 62  LYS   A O    1 
ATOM   919  C CB   . LYS   A 1 65  ? 21.87868 -8.19991  5.44080  1.000 52.85711  ? 62  LYS   A CB   1 
ATOM   920  C CG   . LYS   A 1 65  ? 22.21244 -9.15944  4.30595  1.000 71.32203  ? 62  LYS   A CG   1 
ATOM   921  C CD   . LYS   A 1 65  ? 21.16005 -10.26317 4.19520  1.000 115.89270 ? 62  LYS   A CD   1 
ATOM   922  C CE   . LYS   A 1 65  ? 21.06606 -11.11108 5.46075  1.000 80.60782  ? 62  LYS   A CE   1 
ATOM   923  N NZ   . LYS   A 1 65  ? 22.26458 -11.97142 5.65713  1.000 85.72116  ? 62  LYS   A NZ   1 
ATOM   924  H H    . LYS   A 1 65  ? 21.59898 -6.43017  7.05392  1.000 48.03105  ? 62  LYS   A H    1 
ATOM   925  H HA   . LYS   A 1 65  ? 23.44909 -6.87831  5.31680  1.000 54.90213  ? 62  LYS   A HA   1 
ATOM   926  H HB2  . LYS   A 1 65  ? 22.20050 -8.60311  6.26224  1.000 63.36290  ? 62  LYS   A HB2  1 
ATOM   927  H HB3  . LYS   A 1 65  ? 20.91296 -8.11364  5.46973  1.000 63.36290  ? 62  LYS   A HB3  1 
ATOM   928  H HG2  . LYS   A 1 65  ? 22.23623 -8.67256  3.46734  1.000 85.52081  ? 62  LYS   A HG2  1 
ATOM   929  H HG3  . LYS   A 1 65  ? 23.07388 -9.57229  4.47443  1.000 85.52081  ? 62  LYS   A HG3  1 
ATOM   930  H HD2  . LYS   A 1 65  ? 20.29203 -9.85945  4.03890  1.000 139.00561 ? 62  LYS   A HD2  1 
ATOM   931  H HD3  . LYS   A 1 65  ? 21.39112 -10.84908 3.45749  1.000 139.00561 ? 62  LYS   A HD3  1 
ATOM   932  H HE2  . LYS   A 1 65  ? 20.98603 -10.52578 6.23011  1.000 96.66375  ? 62  LYS   A HE2  1 
ATOM   933  H HE3  . LYS   A 1 65  ? 20.28819 -11.68739 5.40001  1.000 96.66375  ? 62  LYS   A HE3  1 
ATOM   934  H HZ1  . LYS   A 1 65  ? 22.18499 -12.43667 6.41166  1.000 102.79976 ? 62  LYS   A HZ1  1 
ATOM   935  H HZ2  . LYS   A 1 65  ? 22.34750 -12.53802 4.97582  1.000 102.79976 ? 62  LYS   A HZ2  1 
ATOM   936  H HZ3  . LYS   A 1 65  ? 22.99661 -11.46745 5.70441  1.000 102.79976 ? 62  LYS   A HZ3  1 
ATOM   937  N N    . LYS   A 1 66  ? 20.87372 -5.52903  3.99906  1.000 49.83857  ? 63  LYS   A N    1 
ATOM   938  C CA   . LYS   A 1 66  ? 20.31741 -4.95740  2.77990  1.000 62.23323  ? 63  LYS   A CA   1 
ATOM   939  C C    . LYS   A 1 66  ? 20.94170 -3.62068  2.40181  1.000 56.12649  ? 63  LYS   A C    1 
ATOM   940  O O    . LYS   A 1 66  ? 20.72484 -3.15422  1.27804  1.000 68.01732  ? 63  LYS   A O    1 
ATOM   941  C CB   . LYS   A 1 66  ? 18.80382 -4.77761  2.93346  1.000 54.79166  ? 63  LYS   A CB   1 
ATOM   942  C CG   . LYS   A 1 66  ? 18.05801 -6.04168  3.33966  1.000 67.55482  ? 63  LYS   A CG   1 
ATOM   943  C CD   . LYS   A 1 66  ? 16.62504 -5.72754  3.74656  1.000 75.94208  ? 63  LYS   A CD   1 
ATOM   944  C CE   . LYS   A 1 66  ? 15.88945 -6.97126  4.22079  1.000 91.73847  ? 63  LYS   A CE   1 
ATOM   945  N NZ   . LYS   A 1 66  ? 15.73047 -7.98006  3.13723  1.000 106.32341 ? 63  LYS   A NZ   1 
ATOM   946  H H    . LYS   A 1 66  ? 20.36736 -5.43557  4.68787  1.000 59.74066  ? 63  LYS   A H    1 
ATOM   947  H HA   . LYS   A 1 66  ? 20.48129 -5.57629  2.05120  1.000 74.61425  ? 63  LYS   A HA   1 
ATOM   948  H HB2  . LYS   A 1 66  ? 18.63955 -4.10800  3.61577  1.000 65.68436  ? 63  LYS   A HB2  1 
ATOM   949  H HB3  . LYS   A 1 66  ? 18.43973 -4.48224  2.08429  1.000 65.68436  ? 63  LYS   A HB3  1 
ATOM   950  H HG2  . LYS   A 1 66  ? 18.03569 -6.65779  2.59079  1.000 81.00016  ? 63  LYS   A HG2  1 
ATOM   951  H HG3  . LYS   A 1 66  ? 18.50754 -6.45301  4.09440  1.000 81.00016  ? 63  LYS   A HG3  1 
ATOM   952  H HD2  . LYS   A 1 66  ? 16.63167 -5.08329  4.47168  1.000 91.06487  ? 63  LYS   A HD2  1 
ATOM   953  H HD3  . LYS   A 1 66  ? 16.14773 -5.36420  2.98429  1.000 91.06487  ? 63  LYS   A HD3  1 
ATOM   954  H HE2  . LYS   A 1 66  ? 16.39018 -7.38096  4.94351  1.000 110.02053 ? 63  LYS   A HE2  1 
ATOM   955  H HE3  . LYS   A 1 66  ? 15.00550 -6.71938  4.53075  1.000 110.02053 ? 63  LYS   A HE3  1 
ATOM   956  H HZ1  . LYS   A 1 66  ? 15.30322 -7.61866  2.44517  1.000 127.52247 ? 63  LYS   A HZ1  1 
ATOM   957  H HZ2  . LYS   A 1 66  ? 16.52917 -8.26483  2.86688  1.000 127.52247 ? 63  LYS   A HZ2  1 
ATOM   958  H HZ3  . LYS   A 1 66  ? 15.26152 -8.67538  3.43509  1.000 127.52247 ? 63  LYS   A HZ3  1 
ATOM   959  N N    . GLU   A 1 67  ? 21.69965 -2.99328  3.30116  1.000 55.62171  ? 64  GLU   A N    1 
ATOM   960  C CA   . GLU   A 1 67  ? 22.30656 -1.69436  3.04547  1.000 53.51439  ? 64  GLU   A CA   1 
ATOM   961  C C    . GLU   A 1 67  ? 23.79807 -1.79961  2.74966  1.000 51.42715  ? 64  GLU   A C    1 
ATOM   962  O O    . GLU   A 1 67  ? 24.52612 -0.81077  2.88969  1.000 55.56170  ? 64  GLU   A O    1 
ATOM   963  C CB   . GLU   A 1 67  ? 22.06190 -0.76006  4.23105  1.000 56.14366  ? 64  GLU   A CB   1 
ATOM   964  C CG   . GLU   A 1 67  ? 20.59275 -0.43770  4.45393  1.000 72.65115  ? 64  GLU   A CG   1 
ATOM   965  C CD   . GLU   A 1 67  ? 20.37274 0.55373   5.57832  1.000 88.94306  ? 64  GLU   A CD   1 
ATOM   966  O OE1  . GLU   A 1 67  ? 20.82764 0.28434   6.70989  1.000 99.30847  ? 64  GLU   A OE1  1 
ATOM   967  O OE2  . GLU   A 1 67  ? 19.74953 1.60703   5.32780  1.000 88.22930  ? 64  GLU   A OE2  1 
ATOM   968  H H    A GLU   A 1 67  ? 21.87823 -3.30900  4.08093  0.590 66.68042  ? 64  GLU   A H    1 
ATOM   969  H H    B GLU   A 1 67  ? 21.87823 -3.30900  4.08093  0.410 66.68042  ? 64  GLU   A H    1 
ATOM   970  H HA   . GLU   A 1 67  ? 21.88175 -1.30327  2.26606  1.000 64.15164  ? 64  GLU   A HA   1 
ATOM   971  H HB2  . GLU   A 1 67  ? 22.39952 -1.18171  5.03674  1.000 67.30677  ? 64  GLU   A HB2  1 
ATOM   972  H HB3  . GLU   A 1 67  ? 22.52910 0.07519   4.07298  1.000 67.30677  ? 64  GLU   A HB3  1 
ATOM   973  H HG2  . GLU   A 1 67  ? 20.22647 -0.05527  3.64123  1.000 87.11575  ? 64  GLU   A HG2  1 
ATOM   974  H HG3  . GLU   A 1 67  ? 20.12058 -1.25480  4.67821  1.000 87.11575  ? 64  GLU   A HG3  1 
ATOM   975  N N    . GLY   A 1 68  ? 24.26508 -2.97646  2.34407  1.000 51.83956  ? 65  GLY   A N    1 
ATOM   976  C CA   . GLY   A 1 68  ? 25.63961 -3.15290  1.94722  1.000 52.22387  ? 65  GLY   A CA   1 
ATOM   977  C C    . GLY   A 1 68  ? 25.93108 -2.44420  0.64063  1.000 62.39885  ? 65  GLY   A C    1 
ATOM   978  O O    . GLY   A 1 68  ? 25.08910 -1.71649  0.10504  1.000 73.65310  ? 65  GLY   A O    1 
ATOM   979  H H    . GLY   A 1 68  ? 23.79212 -3.69286  2.29225  1.000 62.14184  ? 65  GLY   A H    1 
ATOM   980  H HA2  . GLY   A 1 68  ? 26.22463 -2.79332  2.63231  1.000 62.60301  ? 65  GLY   A HA2  1 
ATOM   981  H HA3  . GLY   A 1 68  ? 25.82723 -4.09806  1.83596  1.000 62.60301  ? 65  GLY   A HA3  1 
ATOM   982  N N    . PRO   A 1 69  ? 27.14263 -2.63700  0.09682  1.000 58.55158  ? 66  PRO   A N    1 
ATOM   983  C CA   . PRO   A 1 69  ? 28.21606 -3.44901  0.67516  1.000 53.43713  ? 66  PRO   A CA   1 
ATOM   984  C C    . PRO   A 1 69  ? 29.04153 -2.65527  1.68066  1.000 48.12042  ? 66  PRO   A C    1 
ATOM   985  O O    . PRO   A 1 69  ? 28.96281 -1.42538  1.69682  1.000 47.19620  ? 66  PRO   A O    1 
ATOM   986  C CB   . PRO   A 1 69  ? 29.04847 -3.82836  -0.54620 1.000 63.95016  ? 66  PRO   A CB   1 
ATOM   987  C CG   . PRO   A 1 69  ? 28.92845 -2.63426  -1.43733 1.000 66.91434  ? 66  PRO   A CG   1 
ATOM   988  C CD   . PRO   A 1 69  ? 27.54859 -2.04675  -1.19285 1.000 61.18403  ? 66  PRO   A CD   1 
ATOM   989  H HA   . PRO   A 1 69  ? 27.87638 -4.25480  1.09494  1.000 64.05893  ? 66  PRO   A HA   1 
ATOM   990  H HB2  . PRO   A 1 69  ? 29.97056 -3.98463  -0.28886 1.000 76.67457  ? 66  PRO   A HB2  1 
ATOM   991  H HB3  . PRO   A 1 69  ? 28.68298 -4.62136  -0.96864 1.000 76.67457  ? 66  PRO   A HB3  1 
ATOM   992  H HG2  . PRO   A 1 69  ? 29.61786 -1.99049  -1.21112 1.000 80.23158  ? 66  PRO   A HG2  1 
ATOM   993  H HG3  . PRO   A 1 69  ? 29.02247 -2.90969  -2.36264 1.000 80.23158  ? 66  PRO   A HG3  1 
ATOM   994  H HD2  . PRO   A 1 69  ? 27.59275 -1.07981  -1.12981 1.000 73.35521  ? 66  PRO   A HD2  1 
ATOM   995  H HD3  . PRO   A 1 69  ? 26.93476 -2.30556  -1.89793 1.000 73.35521  ? 66  PRO   A HD3  1 
ATOM   996  N N    . TYR   A 1 70  ? 29.82286 -3.34636  2.50403  1.000 35.75793  ? 67  TYR   A N    1 
ATOM   997  C CA   . TYR   A 1 70  ? 30.65037 -2.70949  3.51692  1.000 33.13852  ? 67  TYR   A CA   1 
ATOM   998  C C    . TYR   A 1 70  ? 32.12240 -2.91279  3.19251  1.000 26.66282  ? 67  TYR   A C    1 
ATOM   999  O O    . TYR   A 1 70  ? 32.52943 -3.98814  2.74174  1.000 31.09472  ? 67  TYR   A O    1 
ATOM   1000 C CB   . TYR   A 1 70  ? 30.33811 -3.26439  4.90756  1.000 31.05856  ? 67  TYR   A CB   1 
ATOM   1001 C CG   . TYR   A 1 70  ? 28.92297 -2.98850  5.35031  1.000 29.45068  ? 67  TYR   A CG   1 
ATOM   1002 C CD1  . TYR   A 1 70  ? 28.60662 -1.82822  6.03974  1.000 30.63067  ? 67  TYR   A CD1  1 
ATOM   1003 C CD2  . TYR   A 1 70  ? 27.90034 -3.88308  5.06845  1.000 29.17002  ? 67  TYR   A CD2  1 
ATOM   1004 C CE1  . TYR   A 1 70  ? 27.31210 -1.56807  6.44189  1.000 32.86920  ? 67  TYR   A CE1  1 
ATOM   1005 C CE2  . TYR   A 1 70  ? 26.60311 -3.63241  5.46536  1.000 30.68711  ? 67  TYR   A CE2  1 
ATOM   1006 C CZ   . TYR   A 1 70  ? 26.31350 -2.47307  6.15187  1.000 32.58560  ? 67  TYR   A CZ   1 
ATOM   1007 O OH   . TYR   A 1 70  ? 25.02245 -2.21672  6.55296  1.000 35.55078  ? 67  TYR   A OH   1 
ATOM   1008 H H    . TYR   A 1 70  ? 29.89041 -4.20364  2.49316  1.000 42.84389  ? 67  TYR   A H    1 
ATOM   1009 H HA   . TYR   A 1 70  ? 30.47415 -1.75566  3.52436  1.000 39.70060  ? 67  TYR   A HA   1 
ATOM   1010 H HB2  . TYR   A 1 70  ? 30.46647 -4.22582  4.89859  1.000 37.20465  ? 67  TYR   A HB2  1 
ATOM   1011 H HB3  . TYR   A 1 70  ? 30.93777 -2.85563  5.55116  1.000 37.20465  ? 67  TYR   A HB3  1 
ATOM   1012 H HD1  . TYR   A 1 70  ? 29.27789 -1.21477  6.23459  1.000 36.69118  ? 67  TYR   A HD1  1 
ATOM   1013 H HD2  . TYR   A 1 70  ? 28.09284 -4.66536  4.60382  1.000 34.93840  ? 67  TYR   A HD2  1 
ATOM   1014 H HE1  . TYR   A 1 70  ? 27.11469 -0.78664  6.90590  1.000 39.37741  ? 67  TYR   A HE1  1 
ATOM   1015 H HE2  . TYR   A 1 70  ? 25.92823 -4.24200  5.27086  1.000 36.75891  ? 67  TYR   A HE2  1 
ATOM   1016 H HH   . TYR   A 1 70  ? 24.51407 -2.83449  6.29701  1.000 42.59531  ? 67  TYR   A HH   1 
ATOM   1017 N N    . ASP   A 1 71  ? 32.91576 -1.86676  3.42354  1.000 25.58411  ? 68  ASP   A N    1 
ATOM   1018 C CA   . ASP   A 1 71  ? 34.34708 -1.94555  3.17208  1.000 27.15136  ? 68  ASP   A CA   1 
ATOM   1019 C C    . ASP   A 1 71  ? 35.06228 -2.81963  4.19291  1.000 27.18910  ? 68  ASP   A C    1 
ATOM   1020 O O    . ASP   A 1 71  ? 36.14360 -3.33744  3.89498  1.000 27.45642  ? 68  ASP   A O    1 
ATOM   1021 C CB   . ASP   A 1 71  ? 34.94280 -0.53914  3.16502  1.000 30.14517  ? 68  ASP   A CB   1 
ATOM   1022 C CG   . ASP   A 1 71  ? 34.30638 0.35392   2.11749  1.000 32.15567  ? 68  ASP   A CG   1 
ATOM   1023 O OD1  . ASP   A 1 71  ? 34.59480 0.16265   0.91833  1.000 38.00566  ? 68  ASP   A OD1  1 
ATOM   1024 O OD2  . ASP   A 1 71  ? 33.50190 1.23200   2.49342  1.000 29.54370  ? 68  ASP   A OD2  1 
ATOM   1025 H H    . ASP   A 1 71  ? 32.64904 -1.10634  3.72390  1.000 30.63531  ? 68  ASP   A H    1 
ATOM   1026 H HA   . ASP   A 1 71  ? 34.49751 -2.33785  2.29779  1.000 32.51601  ? 68  ASP   A HA   1 
ATOM   1027 H HB2  . ASP   A 1 71  ? 34.80324 -0.13106  4.03387  1.000 36.10858  ? 68  ASP   A HB2  1 
ATOM   1028 H HB3  . ASP   A 1 71  ? 35.89213 -0.59759  2.97458  1.000 36.10858  ? 68  ASP   A HB3  1 
ATOM   1029 N N    . VAL   A 1 72  ? 34.48973 -2.99646  5.38088  1.000 26.29445  ? 69  VAL   A N    1 
ATOM   1030 C CA   . VAL   A 1 72  ? 35.04405 -3.90451  6.37902  1.000 24.34280  ? 69  VAL   A CA   1 
ATOM   1031 C C    . VAL   A 1 72  ? 33.89576 -4.50621  7.17531  1.000 26.28493  ? 69  VAL   A C    1 
ATOM   1032 O O    . VAL   A 1 72  ? 32.92972 -3.81799  7.51793  1.000 24.91046  ? 69  VAL   A O    1 
ATOM   1033 C CB   . VAL   A 1 72  ? 36.04859 -3.19315  7.31331  1.000 24.67003  ? 69  VAL   A CB   1 
ATOM   1034 C CG1  . VAL   A 1 72  ? 35.36526 -2.08081  8.09716  1.000 26.96651  ? 69  VAL   A CG1  1 
ATOM   1035 C CG2  . VAL   A 1 72  ? 36.69460 -4.19794  8.26376  1.000 27.17112  ? 69  VAL   A CG2  1 
ATOM   1036 H H    . VAL   A 1 72  ? 33.77156 -2.59707  5.63447  1.000 31.48771  ? 69  VAL   A H    1 
ATOM   1037 H HA   . VAL   A 1 72  ? 35.51162 -4.61953  5.91964  1.000 29.14573  ? 69  VAL   A HA   1 
ATOM   1038 H HB   . VAL   A 1 72  ? 36.74587 -2.79206  6.77125  1.000 29.53841  ? 69  VAL   A HB   1 
ATOM   1039 H HG11 . VAL   A 1 72  ? 36.04238 -1.53698  8.52919  1.000 32.29418  ? 69  VAL   A HG11 1 
ATOM   1040 H HG12 . VAL   A 1 72  ? 34.84499 -1.53692  7.48527  1.000 32.29418  ? 69  VAL   A HG12 1 
ATOM   1041 H HG13 . VAL   A 1 72  ? 34.78324 -2.47646  8.76471  1.000 32.29418  ? 69  VAL   A HG13 1 
ATOM   1042 H HG21 . VAL   A 1 72  ? 37.39321 -3.75191  8.76765  1.000 32.53972  ? 69  VAL   A HG21 1 
ATOM   1043 H HG22 . VAL   A 1 72  ? 36.01803 -4.54072  8.86844  1.000 32.53972  ? 69  VAL   A HG22 1 
ATOM   1044 H HG23 . VAL   A 1 72  ? 37.07349 -4.92477  7.74505  1.000 32.53972  ? 69  VAL   A HG23 1 
ATOM   1045 N N    . VAL   A 1 73  ? 34.00341 -5.80083  7.45870  1.000 21.50428  ? 70  VAL   A N    1 
ATOM   1046 C CA   . VAL   A 1 73  ? 33.11628 -6.49324  8.38493  1.000 22.23102  ? 70  VAL   A CA   1 
ATOM   1047 C C    . VAL   A 1 73  ? 33.93498 -6.85469  9.61433  1.000 22.68813  ? 70  VAL   A C    1 
ATOM   1048 O O    . VAL   A 1 73  ? 35.00478 -7.46551  9.49615  1.000 21.38560  ? 70  VAL   A O    1 
ATOM   1049 C CB   . VAL   A 1 73  ? 32.49043 -7.74587  7.75077  1.000 25.73597  ? 70  VAL   A CB   1 
ATOM   1050 C CG1  . VAL   A 1 73  ? 31.62333 -8.47400  8.76775  1.000 24.35283  ? 70  VAL   A CG1  1 
ATOM   1051 C CG2  . VAL   A 1 73  ? 31.67545 -7.36846  6.52616  1.000 28.99014  ? 70  VAL   A CG2  1 
ATOM   1052 H H    . VAL   A 1 73  ? 34.60195 -6.31402  7.11522  1.000 25.73950  ? 70  VAL   A H    1 
ATOM   1053 H HA   . VAL   A 1 73  ? 32.39285 -5.90262  8.64705  1.000 26.61160  ? 70  VAL   A HA   1 
ATOM   1054 H HB   . VAL   A 1 73  ? 33.19837 -8.34614  7.46900  1.000 30.81754  ? 70  VAL   A HB   1 
ATOM   1055 H HG11 . VAL   A 1 73  ? 31.08514 -9.13660  8.30708  1.000 29.15777  ? 70  VAL   A HG11 1 
ATOM   1056 H HG12 . VAL   A 1 73  ? 32.19685 -8.90808  9.41856  1.000 29.15777  ? 70  VAL   A HG12 1 
ATOM   1057 H HG13 . VAL   A 1 73  ? 31.04823 -7.83059  9.21068  1.000 29.15777  ? 70  VAL   A HG13 1 
ATOM   1058 H HG21 . VAL   A 1 73  ? 31.32273 -8.17585  6.12044  1.000 34.72254  ? 70  VAL   A HG21 1 
ATOM   1059 H HG22 . VAL   A 1 73  ? 30.94644 -6.78928  6.79819  1.000 34.72254  ? 70  VAL   A HG22 1 
ATOM   1060 H HG23 . VAL   A 1 73  ? 32.24875 -6.90480  5.89589  1.000 34.72254  ? 70  VAL   A HG23 1 
ATOM   1061 N N    . VAL   A 1 74  ? 33.43867 -6.47631  10.78871 1.000 22.26378  ? 71  VAL   A N    1 
ATOM   1062 C CA   . VAL   A 1 74  ? 34.18642 -6.58501  12.03535 1.000 21.33025  ? 71  VAL   A CA   1 
ATOM   1063 C C    . VAL   A 1 74  ? 33.49493 -7.59683  12.93545 1.000 21.31499  ? 71  VAL   A C    1 
ATOM   1064 O O    . VAL   A 1 74  ? 32.29415 -7.47840  13.21000 1.000 25.84665  ? 71  VAL   A O    1 
ATOM   1065 C CB   . VAL   A 1 74  ? 34.31154 -5.22104  12.73685 1.000 22.26248  ? 71  VAL   A CB   1 
ATOM   1066 C CG1  . VAL   A 1 74  ? 35.04789 -5.36926  14.05814 1.000 24.94240  ? 71  VAL   A CG1  1 
ATOM   1067 C CG2  . VAL   A 1 74  ? 35.02507 -4.22623  11.83632 1.000 21.42663  ? 71  VAL   A CG2  1 
ATOM   1068 H H    . VAL   A 1 74  ? 32.65124 -6.14560  10.88955 1.000 26.65090  ? 71  VAL   A H    1 
ATOM   1069 H HA   . VAL   A 1 74  ? 35.07753 -6.91502  11.84064 1.000 25.53068  ? 71  VAL   A HA   1 
ATOM   1070 H HB   . VAL   A 1 74  ? 33.42289 -4.87936  12.92245 1.000 26.64935  ? 71  VAL   A HB   1 
ATOM   1071 H HG11 . VAL   A 1 74  ? 35.31149 -4.49049  14.37307 1.000 29.86526  ? 71  VAL   A HG11 1 
ATOM   1072 H HG12 . VAL   A 1 74  ? 34.45739 -5.78852  14.70345 1.000 29.86526  ? 71  VAL   A HG12 1 
ATOM   1073 H HG13 . VAL   A 1 74  ? 35.83379 -5.92116  13.92151 1.000 29.86526  ? 71  VAL   A HG13 1 
ATOM   1074 H HG21 . VAL   A 1 74  ? 35.10108 -3.37798  12.30064 1.000 25.64633  ? 71  VAL   A HG21 1 
ATOM   1075 H HG22 . VAL   A 1 74  ? 35.90797 -4.56808  11.62529 1.000 25.64633  ? 71  VAL   A HG22 1 
ATOM   1076 H HG23 . VAL   A 1 74  ? 34.51098 -4.11249  11.02167 1.000 25.64633  ? 71  VAL   A HG23 1 
ATOM   1077 N N    . LEU   A 1 75  ? 34.25685 -8.58273  13.40072 1.000 21.71502  ? 72  LEU   A N    1 
ATOM   1078 C CA   . LEU   A 1 75  ? 33.74958 -9.60698  14.30491 1.000 19.39554  ? 72  LEU   A CA   1 
ATOM   1079 C C    . LEU   A 1 75  ? 34.40326 -9.44360  15.66866 1.000 22.94153  ? 72  LEU   A C    1 
ATOM   1080 O O    . LEU   A 1 75  ? 35.58714 -9.78415  15.82163 1.000 24.13862  ? 72  LEU   A O    1 
ATOM   1081 C CB   . LEU   A 1 75  ? 34.03217 -11.00363 13.74958 1.000 23.99506  ? 72  LEU   A CB   1 
ATOM   1082 C CG   . LEU   A 1 75  ? 33.49426 -11.32367 12.35541 1.000 20.15372  ? 72  LEU   A CG   1 
ATOM   1083 C CD1  . LEU   A 1 75  ? 33.90122 -12.73415 11.96040 1.000 37.12092  ? 72  LEU   A CD1  1 
ATOM   1084 C CD2  . LEU   A 1 75  ? 31.98624 -11.16739 12.30490 1.000 25.59631  ? 72  LEU   A CD2  1 
ATOM   1085 H H    . LEU   A 1 75  ? 35.08791 -8.68125  13.20264 1.000 25.99239  ? 72  LEU   A H    1 
ATOM   1086 H HA   . LEU   A 1 75  ? 32.79019 -9.50174  14.40188 1.000 23.20902  ? 72  LEU   A HA   1 
ATOM   1087 H HB2  . LEU   A 1 75  ? 34.99443 -11.12070 13.71419 1.000 28.72845  ? 72  LEU   A HB2  1 
ATOM   1088 H HB3  . LEU   A 1 75  ? 33.64143 -11.65037 14.35781 1.000 28.72845  ? 72  LEU   A HB3  1 
ATOM   1089 H HG   . LEU   A 1 75  ? 33.87166 -10.69960 11.71588 1.000 24.11884  ? 72  LEU   A HG   1 
ATOM   1090 H HD11 . LEU   A 1 75  ? 33.53890 -12.93332 11.08293 1.000 44.47948  ? 72  LEU   A HD11 1 
ATOM   1091 H HD12 . LEU   A 1 75  ? 34.86942 -12.78911 11.93875 1.000 44.47948  ? 72  LEU   A HD12 1 
ATOM   1092 H HD13 . LEU   A 1 75  ? 33.54896 -13.35903 12.61335 1.000 44.47948  ? 72  LEU   A HD13 1 
ATOM   1093 H HD21 . LEU   A 1 75  ? 31.67065 -11.43130 11.42647 1.000 30.64995  ? 72  LEU   A HD21 1 
ATOM   1094 H HD22 . LEU   A 1 75  ? 31.58713 -11.73380 12.98372 1.000 30.64995  ? 72  LEU   A HD22 1 
ATOM   1095 H HD23 . LEU   A 1 75  ? 31.75910 -10.23946 12.47297 1.000 30.64995  ? 72  LEU   A HD23 1 
ATOM   1096 N N    . PRO   A 1 76  ? 33.70436 -8.93404  16.68021 1.000 22.85463  ? 73  PRO   A N    1 
ATOM   1097 C CA   . PRO   A 1 76  ? 34.29612 -8.87103  18.01969 1.000 20.20885  ? 73  PRO   A CA   1 
ATOM   1098 C C    . PRO   A 1 76  ? 34.50730 -10.26778 18.58103 1.000 23.29461  ? 73  PRO   A C    1 
ATOM   1099 O O    . PRO   A 1 76  ? 34.02392 -11.27008 18.05073 1.000 19.28170  ? 73  PRO   A O    1 
ATOM   1100 C CB   . PRO   A 1 76  ? 33.26903 -8.08784  18.84536 1.000 23.61667  ? 73  PRO   A CB   1 
ATOM   1101 C CG   . PRO   A 1 76  ? 32.34768 -7.45725  17.84839 1.000 27.06469  ? 73  PRO   A CG   1 
ATOM   1102 C CD   . PRO   A 1 76  ? 32.34790 -8.36217  16.65788 1.000 21.89466  ? 73  PRO   A CD   1 
ATOM   1103 H HA   . PRO   A 1 76  ? 35.13408 -8.38264  18.00523 1.000 24.18499  ? 73  PRO   A HA   1 
ATOM   1104 H HB2  . PRO   A 1 76  ? 32.78480 -8.69460  19.42697 1.000 28.27438  ? 73  PRO   A HB2  1 
ATOM   1105 H HB3  . PRO   A 1 76  ? 33.72062 -7.41131  19.37382 1.000 28.27438  ? 73  PRO   A HB3  1 
ATOM   1106 H HG2  . PRO   A 1 76  ? 31.45684 -7.38692  18.22571 1.000 32.41200  ? 73  PRO   A HG2  1 
ATOM   1107 H HG3  . PRO   A 1 76  ? 32.67750 -6.57672  17.61010 1.000 32.41200  ? 73  PRO   A HG3  1 
ATOM   1108 H HD2  . PRO   A 1 76  ? 31.67718 -9.05680  16.75018 1.000 26.20796  ? 73  PRO   A HD2  1 
ATOM   1109 H HD3  . PRO   A 1 76  ? 32.19627 -7.86100  15.84134 1.000 26.20796  ? 73  PRO   A HD3  1 
ATOM   1110 N N    . GLY   A 1 77  ? 35.24694 -10.31912 19.67689 1.000 22.07879  ? 74  GLY   A N    1 
ATOM   1111 C CA   . GLY   A 1 77  ? 35.50424 -11.55213 20.38765 1.000 18.64351  ? 74  GLY   A CA   1 
ATOM   1112 C C    . GLY   A 1 77  ? 34.51266 -11.79007 21.50230 1.000 23.49614  ? 74  GLY   A C    1 
ATOM   1113 O O    . GLY   A 1 77  ? 33.35347 -11.36998 21.43965 1.000 21.36049  ? 74  GLY   A O    1 
ATOM   1114 H H    A GLY   A 1 77  ? 35.61948 -9.63192  20.03545 0.470 26.42892  ? 74  GLY   A H    1 
ATOM   1115 H H    B GLY   A 1 77  ? 35.61948 -9.63192  20.03545 0.530 26.42892  ? 74  GLY   A H    1 
ATOM   1116 H HA2  . GLY   A 1 77  ? 35.45262 -12.29673 19.76812 1.000 22.30659  ? 74  GLY   A HA2  1 
ATOM   1117 H HA3  . GLY   A 1 77  ? 36.39455 -11.52180 20.77147 1.000 22.30659  ? 74  GLY   A HA3  1 
ATOM   1118 N N    . GLY   A 1 78  ? 34.98520 -12.45233 22.55273 1.000 21.92426  ? 75  GLY   A N    1 
ATOM   1119 C CA   . GLY   A 1 78  ? 34.09765 -13.01279 23.54862 1.000 22.22362  ? 75  GLY   A CA   1 
ATOM   1120 C C    . GLY   A 1 78  ? 33.76113 -14.44105 23.17597 1.000 25.98180  ? 75  GLY   A C    1 
ATOM   1121 O O    . GLY   A 1 78  ? 33.24127 -14.69326 22.08458 1.000 23.25638  ? 75  GLY   A O    1 
ATOM   1122 H H    . GLY   A 1 78  ? 35.82014 -12.58849 22.70742 1.000 26.24349  ? 75  GLY   A H    1 
ATOM   1123 H HA2  . GLY   A 1 78  ? 34.52615 -13.00323 24.41880 1.000 26.60271  ? 75  GLY   A HA2  1 
ATOM   1124 H HA3  . GLY   A 1 78  ? 33.27917 -12.49420 23.59394 1.000 26.60271  ? 75  GLY   A HA3  1 
ATOM   1125 N N    . ASN   A 1 79  ? 34.06993 -15.38691 24.06475 1.000 21.92329  ? 76  ASN   A N    1 
ATOM   1126 C CA   . ASN   A 1 79  ? 33.90461 -16.79820 23.73140 1.000 23.82538  ? 76  ASN   A CA   1 
ATOM   1127 C C    . ASN   A 1 79  ? 32.48025 -17.09703 23.28015 1.000 22.79508  ? 76  ASN   A C    1 
ATOM   1128 O O    . ASN   A 1 79  ? 32.26548 -17.65643 22.19923 1.000 25.31731  ? 76  ASN   A O    1 
ATOM   1129 C CB   . ASN   A 1 79  ? 34.28700 -17.66699 24.92960 1.000 26.38847  ? 76  ASN   A CB   1 
ATOM   1130 C CG   . ASN   A 1 79  ? 35.78901 -17.76797 25.12035 1.000 40.42964  ? 76  ASN   A CG   1 
ATOM   1131 O OD1  . ASN   A 1 79  ? 36.55945 -17.58384 24.17857 1.000 60.52405  ? 76  ASN   A OD1  1 
ATOM   1132 N ND2  . ASN   A 1 79  ? 36.21208 -18.06748 26.34191 1.000 48.75146  ? 76  ASN   A ND2  1 
ATOM   1133 H H    . ASN   A 1 79  ? 34.37261 -15.23890 24.85600 1.000 26.24232  ? 76  ASN   A H    1 
ATOM   1134 H HA   . ASN   A 1 79  ? 34.50108 -17.01637 22.99825 1.000 28.52483  ? 76  ASN   A HA   1 
ATOM   1135 H HB2  . ASN   A 1 79  ? 33.90691 -17.28156 25.73450 1.000 31.60054  ? 76  ASN   A HB2  1 
ATOM   1136 H HB3  . ASN   A 1 79  ? 33.94010 -18.56277 24.79493 1.000 31.60054  ? 76  ASN   A HB3  1 
ATOM   1137 H HD21 . ASN   A 1 79  ? 37.05456 -18.13608 26.50043 1.000 58.43613  ? 76  ASN   A HD21 1 
ATOM   1138 H HD22 . ASN   A 1 79  ? 35.64378 -18.19299 26.97507 1.000 58.43613  ? 76  ASN   A HD22 1 
ATOM   1139 N N    . LEU   A 1 80  ? 31.48891 -16.72100 24.09104 1.000 22.97143  ? 77  LEU   A N    1 
ATOM   1140 C CA   . LEU   A 1 80  ? 30.10563 -17.02007 23.73538 1.000 26.65136  ? 77  LEU   A CA   1 
ATOM   1141 C C    . LEU   A 1 80  ? 29.65542 -16.19306 22.53779 1.000 27.74738  ? 77  LEU   A C    1 
ATOM   1142 O O    . LEU   A 1 80  ? 28.88896 -16.67627 21.69626 1.000 24.55915  ? 77  LEU   A O    1 
ATOM   1143 C CB   . LEU   A 1 80  ? 29.19609 -16.78486 24.93974 1.000 32.20948  ? 77  LEU   A CB   1 
ATOM   1144 C CG   . LEU   A 1 80  ? 29.56077 -17.62192 26.17049 1.000 39.90482  ? 77  LEU   A CG   1 
ATOM   1145 C CD1  . LEU   A 1 80  ? 28.61978 -17.33261 27.32836 1.000 57.56960  ? 77  LEU   A CD1  1 
ATOM   1146 C CD2  . LEU   A 1 80  ? 29.55991 -19.10846 25.83940 1.000 45.79290  ? 77  LEU   A CD2  1 
ATOM   1147 H H    . LEU   A 1 80  ? 31.58963 -16.30148 24.83498 1.000 27.50009  ? 77  LEU   A H    1 
ATOM   1148 H HA   . LEU   A 1 80  ? 30.03510 -17.95605 23.49072 1.000 31.91600  ? 77  LEU   A HA   1 
ATOM   1149 H HB2  . LEU   A 1 80  ? 29.25068 -15.84971 25.19156 1.000 38.58575  ? 77  LEU   A HB2  1 
ATOM   1150 H HB3  . LEU   A 1 80  ? 28.28603 -17.00843 24.68933 1.000 38.58575  ? 77  LEU   A HB3  1 
ATOM   1151 H HG   . LEU   A 1 80  ? 30.45744 -17.37802 26.44869 1.000 47.82015  ? 77  LEU   A HG   1 
ATOM   1152 H HD11 . LEU   A 1 80  ? 28.85656 -17.90154 28.07746 1.000 69.01789  ? 77  LEU   A HD11 1 
ATOM   1153 H HD12 . LEU   A 1 80  ? 28.70695 -16.40008 27.58072 1.000 69.01789  ? 77  LEU   A HD12 1 
ATOM   1154 H HD13 . LEU   A 1 80  ? 27.70923 -17.51587 27.04867 1.000 69.01789  ? 77  LEU   A HD13 1 
ATOM   1155 H HD21 . LEU   A 1 80  ? 30.31895 -19.30526 25.26840 1.000 54.88586  ? 77  LEU   A HD21 1 
ATOM   1156 H HD22 . LEU   A 1 80  ? 29.62575 -19.61562 26.66364 1.000 54.88586  ? 77  LEU   A HD22 1 
ATOM   1157 H HD23 . LEU   A 1 80  ? 28.73451 -19.32925 25.38021 1.000 54.88586  ? 77  LEU   A HD23 1 
ATOM   1158 N N    . GLY   A 1 81  ? 30.12764 -14.95015 22.43686 1.000 21.27566  ? 78  GLY   A N    1 
ATOM   1159 C CA   . GLY   A 1 81  ? 29.82158 -14.15520 21.25992 1.000 25.13156  ? 78  GLY   A CA   1 
ATOM   1160 C C    . GLY   A 1 81  ? 30.32431 -14.80573 19.98661 1.000 24.08155  ? 78  GLY   A C    1 
ATOM   1161 O O    . GLY   A 1 81  ? 29.60308 -14.89234 18.98975 1.000 22.40952  ? 78  GLY   A O    1 
ATOM   1162 H H    . GLY   A 1 81  ? 30.61623 -14.55569 23.02446 1.000 25.46517  ? 78  GLY   A H    1 
ATOM   1163 H HA2  . GLY   A 1 81  ? 28.86085 -14.04217 21.18829 1.000 30.09224  ? 78  GLY   A HA2  1 
ATOM   1164 H HA3  . GLY   A 1 81  ? 30.23686 -13.28259 21.34351 1.000 30.09224  ? 78  GLY   A HA3  1 
ATOM   1165 N N    . ALA   A 1 82  ? 31.57343 -15.27867 20.00656 1.000 22.96043  ? 79  ALA   A N    1 
ATOM   1166 C CA   . ALA   A 1 82  ? 32.13934 -15.92440 18.82697 1.000 26.33195  ? 79  ALA   A CA   1 
ATOM   1167 C C    . ALA   A 1 82  ? 31.38004 -17.19768 18.47814 1.000 26.70019  ? 79  ALA   A C    1 
ATOM   1168 O O    . ALA   A 1 82  ? 31.19969 -17.51824 17.29747 1.000 27.09612  ? 79  ALA   A O    1 
ATOM   1169 C CB   . ALA   A 1 82  ? 33.61939 -16.22949 19.05623 1.000 25.94861  ? 79  ALA   A CB   1 
ATOM   1170 H H    . ALA   A 1 82  ? 32.10467 -15.23785 20.68163 1.000 27.48689  ? 79  ALA   A H    1 
ATOM   1171 H HA   . ALA   A 1 82  ? 32.06992 -15.31657 18.07422 1.000 31.53271  ? 79  ALA   A HA   1 
ATOM   1172 H HB1  . ALA   A 1 82  ? 33.98095 -16.65402 18.26254 1.000 31.07270  ? 79  ALA   A HB1  1 
ATOM   1173 H HB2  . ALA   A 1 82  ? 34.08965 -15.39922 19.23061 1.000 31.07270  ? 79  ALA   A HB2  1 
ATOM   1174 H HB3  . ALA   A 1 82  ? 33.70496 -16.82432 19.81764 1.000 31.07270  ? 79  ALA   A HB3  1 
ATOM   1175 N N    A GLN   A 1 83  ? 30.92819 -17.93891 19.49284 0.491 27.10703  ? 80  GLN   A N    1 
ATOM   1176 N N    B GLN   A 1 83  ? 30.93312 -17.94240 19.49179 0.509 27.08494  ? 80  GLN   A N    1 
ATOM   1177 C CA   A GLN   A 1 83  ? 30.16413 -19.15496 19.23359 0.491 30.63030  ? 80  GLN   A CA   1 
ATOM   1178 C CA   B GLN   A 1 83  ? 30.16442 -19.15377 19.22706 0.509 30.61265  ? 80  GLN   A CA   1 
ATOM   1179 C C    A GLN   A 1 83  ? 28.84980 -18.83668 18.53194 0.491 31.79785  ? 80  GLN   A C    1 
ATOM   1180 C C    B GLN   A 1 83  ? 28.85877 -18.82443 18.51568 0.509 31.82739  ? 80  GLN   A C    1 
ATOM   1181 O O    A GLN   A 1 83  ? 28.43622 -19.55514 17.61404 0.491 28.97470  ? 80  GLN   A O    1 
ATOM   1182 O O    B GLN   A 1 83  ? 28.46004 -19.52260 17.57580 0.509 28.71018  ? 80  GLN   A O    1 
ATOM   1183 C CB   A GLN   A 1 83  ? 29.90938 -19.90239 20.54321 0.491 33.52020  ? 80  GLN   A CB   1 
ATOM   1184 C CB   B GLN   A 1 83  ? 29.89170 -19.89896 20.53385 0.509 33.50417  ? 80  GLN   A CB   1 
ATOM   1185 C CG   A GLN   A 1 83  ? 31.16363 -20.49240 21.17220 0.491 38.17871  ? 80  GLN   A CG   1 
ATOM   1186 C CG   B GLN   A 1 83  ? 29.15406 -21.21863 20.35524 0.509 38.93302  ? 80  GLN   A CG   1 
ATOM   1187 C CD   A GLN   A 1 83  ? 30.90496 -21.10403 22.53611 0.491 53.81353  ? 80  GLN   A CD   1 
ATOM   1188 C CD   B GLN   A 1 83  ? 28.80664 -21.87611 21.67673 0.509 53.41111  ? 80  GLN   A CD   1 
ATOM   1189 O OE1  A GLN   A 1 83  ? 29.77971 -21.48756 22.85445 0.491 68.16301  ? 80  GLN   A OE1  1 
ATOM   1190 O OE1  B GLN   A 1 83  ? 29.27709 -21.45756 22.73427 0.509 67.25739  ? 80  GLN   A OE1  1 
ATOM   1191 N NE2  A GLN   A 1 83  ? 31.94934 -21.19310 23.35229 0.491 42.85264  ? 80  GLN   A NE2  1 
ATOM   1192 N NE2  B GLN   A 1 83  ? 27.97466 -22.90984 21.62276 0.509 68.07663  ? 80  GLN   A NE2  1 
ATOM   1193 H H    A GLN   A 1 83  ? 31.04917 -17.76132 20.32557 0.491 32.46281  ? 80  GLN   A H    1 
ATOM   1194 H H    B GLN   A 1 83  ? 31.05971 -17.77026 20.32482 0.509 32.43630  ? 80  GLN   A H    1 
ATOM   1195 H HA   A GLN   A 1 83  ? 30.68197 -19.73524 18.65392 0.491 36.69073  ? 80  GLN   A HA   1 
ATOM   1196 H HA   B GLN   A 1 83  ? 30.68393 -19.73844 18.65333 0.509 36.66955  ? 80  GLN   A HA   1 
ATOM   1197 H HB2  A GLN   A 1 83  ? 29.52046 -19.28550 21.18281 0.491 40.15862  ? 80  GLN   A HB2  1 
ATOM   1198 H HB2  B GLN   A 1 83  ? 30.73945 -20.09125 20.96424 0.509 40.13937  ? 80  GLN   A HB2  1 
ATOM   1199 H HB3  A GLN   A 1 83  ? 29.29444 -20.63233 20.37018 0.491 40.15862  ? 80  GLN   A HB3  1 
ATOM   1200 H HB3  B GLN   A 1 83  ? 29.34973 -19.33367 21.10622 0.509 40.13937  ? 80  GLN   A HB3  1 
ATOM   1201 H HG2  A GLN   A 1 83  ? 31.51046 -21.18841 20.59239 0.491 45.74882  ? 80  GLN   A HG2  1 
ATOM   1202 H HG2  B GLN   A 1 83  ? 28.32773 -21.05682 19.87368 0.509 46.65400  ? 80  GLN   A HG2  1 
ATOM   1203 H HG3  A GLN   A 1 83  ? 31.82399 -19.78995 21.27898 0.491 45.74882  ? 80  GLN   A HG3  1 
ATOM   1204 H HG3  B GLN   A 1 83  ? 29.71592 -21.83008 19.85391 0.509 46.65400  ? 80  GLN   A HG3  1 
ATOM   1205 H HE21 A GLN   A 1 83  ? 32.72047 -20.91138 23.09618 0.491 51.35754  ? 80  GLN   A HE21 1 
ATOM   1206 H HE21 B GLN   A 1 83  ? 27.66363 -23.17239 20.86518 0.509 81.62633  ? 80  GLN   A HE21 1 
ATOM   1207 H HE22 A GLN   A 1 83  ? 31.85430 -21.53247 24.13675 0.491 51.35754  ? 80  GLN   A HE22 1 
ATOM   1208 H HE22 B GLN   A 1 83  ? 27.74692 -23.31670 22.34539 0.509 81.62633  ? 80  GLN   A HE22 1 
ATOM   1209 N N    . ASN   A 1 84  ? 28.18009 -17.75951 18.94704 1.000 25.31222  ? 81  ASN   A N    1 
ATOM   1210 C CA   . ASN   A 1 84  ? 26.94189 -17.36306 18.28658 1.000 28.31000  ? 81  ASN   A CA   1 
ATOM   1211 C C    . ASN   A 1 84  ? 27.20564 -16.91750 16.85336 1.000 24.25033  ? 81  ASN   A C    1 
ATOM   1212 O O    . ASN   A 1 84  ? 26.41173 -17.20955 15.95119 1.000 26.75618  ? 81  ASN   A O    1 
ATOM   1213 C CB   . ASN   A 1 84  ? 26.25688 -16.25688 19.08859 1.000 23.99184  ? 81  ASN   A CB   1 
ATOM   1214 C CG   . ASN   A 1 84  ? 25.62487 -16.77361 20.36781 1.000 33.47608  ? 81  ASN   A CG   1 
ATOM   1215 O OD1  . ASN   A 1 84  ? 24.97970 -17.82127 20.37242 1.000 37.81527  ? 81  ASN   A OD1  1 
ATOM   1216 N ND2  . ASN   A 1 84  ? 25.81466 -16.04434 21.46238 1.000 37.75365  ? 81  ASN   A ND2  1 
ATOM   1217 H H    A ASN   A 1 84  ? 28.41880 -17.25087 19.59811 0.491 30.30903  ? 81  ASN   A H    1 
ATOM   1218 H H    B ASN   A 1 84  ? 28.41214 -17.26022 19.60769 0.509 30.30903  ? 81  ASN   A H    1 
ATOM   1219 H HA   . ASN   A 1 84  ? 26.33879 -18.12212 18.25490 1.000 33.90638  ? 81  ASN   A HA   1 
ATOM   1220 H HB2  . ASN   A 1 84  ? 26.91431 -15.58494 19.32769 1.000 28.72458  ? 81  ASN   A HB2  1 
ATOM   1221 H HB3  . ASN   A 1 84  ? 25.55765 -15.85887 18.54677 1.000 28.72458  ? 81  ASN   A HB3  1 
ATOM   1222 H HD21 . ASN   A 1 84  ? 25.47583 -16.29683 22.21141 1.000 45.23876  ? 81  ASN   A HD21 1 
ATOM   1223 H HD22 . ASN   A 1 84  ? 26.27632 -15.31990 21.42171 1.000 45.23876  ? 81  ASN   A HD22 1 
ATOM   1224 N N    . LEU   A 1 85  ? 28.32077 -16.21927 16.62104 1.000 25.87154  ? 82  LEU   A N    1 
ATOM   1225 C CA   . LEU   A 1 85  ? 28.68638 -15.84966 15.25720 1.000 25.75019  ? 82  LEU   A CA   1 
ATOM   1226 C C    . LEU   A 1 85  ? 28.97570 -17.08574 14.41516 1.000 32.09999  ? 82  LEU   A C    1 
ATOM   1227 O O    . LEU   A 1 85  ? 28.63746 -17.13109 13.22658 1.000 25.79377  ? 82  LEU   A O    1 
ATOM   1228 C CB   . LEU   A 1 85  ? 29.90403 -14.92498 15.26668 1.000 25.66425  ? 82  LEU   A CB   1 
ATOM   1229 C CG   . LEU   A 1 85  ? 29.75061 -13.54138 15.90019 1.000 28.88806  ? 82  LEU   A CG   1 
ATOM   1230 C CD1  . LEU   A 1 85  ? 31.10268 -12.84450 15.94730 1.000 26.76085  ? 82  LEU   A CD1  1 
ATOM   1231 C CD2  . LEU   A 1 85  ? 28.74405 -12.69782 15.13832 1.000 32.38825  ? 82  LEU   A CD2  1 
ATOM   1232 H H    . LEU   A 1 85  ? 28.87136 -15.95311 17.22570 1.000 30.98022  ? 82  LEU   A H    1 
ATOM   1233 H HA   . LEU   A 1 85  ? 27.94468 -15.36914 14.85736 1.000 30.83460  ? 82  LEU   A HA   1 
ATOM   1234 H HB2  . LEU   A 1 85  ? 30.61264 -15.37623 15.75161 1.000 30.73147  ? 82  LEU   A HB2  1 
ATOM   1235 H HB3  . LEU   A 1 85  ? 30.17179 -14.78130 14.34551 1.000 30.73147  ? 82  LEU   A HB3  1 
ATOM   1236 H HG   . LEU   A 1 85  ? 29.41783 -13.64286 16.80566 1.000 34.60004  ? 82  LEU   A HG   1 
ATOM   1237 H HD11 . LEU   A 1 85  ? 30.98298 -11.94597 16.29256 1.000 32.04739  ? 82  LEU   A HD11 1 
ATOM   1238 H HD12 . LEU   A 1 85  ? 31.69622 -13.34571 16.52815 1.000 32.04739  ? 82  LEU   A HD12 1 
ATOM   1239 H HD13 . LEU   A 1 85  ? 31.47055 -12.80799 15.05051 1.000 32.04739  ? 82  LEU   A HD13 1 
ATOM   1240 H HD21 . LEU   A 1 85  ? 28.73027 -11.80457 15.51622 1.000 38.80028  ? 82  LEU   A HD21 1 
ATOM   1241 H HD22 . LEU   A 1 85  ? 29.00691 -12.65831 14.20545 1.000 38.80028  ? 82  LEU   A HD22 1 
ATOM   1242 H HD23 . LEU   A 1 85  ? 27.86689 -13.10422 15.21789 1.000 38.80028  ? 82  LEU   A HD23 1 
ATOM   1243 N N    . SER   A 1 86  ? 29.60372 -18.09958 15.01753 1.000 25.38878  ? 83  SER   A N    1 
ATOM   1244 C CA   . SER   A 1 86  ? 29.97737 -19.29582 14.27199 1.000 29.94669  ? 83  SER   A CA   1 
ATOM   1245 C C    . SER   A 1 86  ? 28.75995 -20.11844 13.87274 1.000 30.81596  ? 83  SER   A C    1 
ATOM   1246 O O    . SER   A 1 86  ? 28.80374 -20.83596 12.86765 1.000 33.10898  ? 83  SER   A O    1 
ATOM   1247 C CB   . SER   A 1 86  ? 30.93408 -20.15290 15.10293 1.000 25.28453  ? 83  SER   A CB   1 
ATOM   1248 O OG   . SER   A 1 86  ? 32.12196 -19.44602 15.41052 1.000 32.68881  ? 83  SER   A OG   1 
ATOM   1249 H H    . SER   A 1 86  ? 29.82173 -18.11705 15.84926 1.000 30.40091  ? 83  SER   A H    1 
ATOM   1250 H HA   . SER   A 1 86  ? 30.43519 -19.02226 13.46177 1.000 35.87040  ? 83  SER   A HA   1 
ATOM   1251 H HB2  . SER   A 1 86  ? 30.49391 -20.40239 15.93051 1.000 30.27581  ? 83  SER   A HB2  1 
ATOM   1252 H HB3  . SER   A 1 86  ? 31.16383 -20.94776 14.59665 1.000 30.27581  ? 83  SER   A HB3  1 
ATOM   1253 H HG   . SER   A 1 86  ? 31.93728 -18.74416 15.83345 1.000 39.16094  ? 83  SER   A HG   1 
ATOM   1254 N N    . GLU   A 1 87  ? 27.67461 -20.03332 14.63972 1.000 28.18136  ? 84  GLU   A N    1 
ATOM   1255 C CA   . GLU   A 1 87  ? 26.48170 -20.82876 14.38715 1.000 32.35020  ? 84  GLU   A CA   1 
ATOM   1256 C C    . GLU   A 1 87  ? 25.48327 -20.14960 13.45839 1.000 36.50487  ? 84  GLU   A C    1 
ATOM   1257 O O    . GLU   A 1 87  ? 24.49992 -20.78638 13.06633 1.000 39.96795  ? 84  GLU   A O    1 
ATOM   1258 C CB   . GLU   A 1 87  ? 25.77685 -21.15344 15.70947 1.000 42.33750  ? 84  GLU   A CB   1 
ATOM   1259 C CG   . GLU   A 1 87  ? 26.55627 -22.07038 16.63545 1.000 42.01090  ? 84  GLU   A CG   1 
ATOM   1260 C CD   . GLU   A 1 87  ? 25.89990 -22.20838 17.99613 1.000 65.57079  ? 84  GLU   A CD   1 
ATOM   1261 O OE1  . GLU   A 1 87  ? 24.74529 -21.75536 18.15022 1.000 61.08531  ? 84  GLU   A OE1  1 
ATOM   1262 O OE2  . GLU   A 1 87  ? 26.53943 -22.76536 18.91262 1.000 78.39433  ? 84  GLU   A OE2  1 
ATOM   1263 H H    . GLU   A 1 87  ? 27.60623 -19.51381 15.32166 1.000 33.75200  ? 84  GLU   A H    1 
ATOM   1264 H HA   . GLU   A 1 87  ? 26.75770 -21.66026 13.97082 1.000 38.75461  ? 84  GLU   A HA   1 
ATOM   1265 H HB2  . GLU   A 1 87  ? 25.61806 -20.32355 16.18589 1.000 50.73937  ? 84  GLU   A HB2  1 
ATOM   1266 H HB3  . GLU   A 1 87  ? 24.93298 -21.58826 15.51018 1.000 50.73937  ? 84  GLU   A HB3  1 
ATOM   1267 H HG2  . GLU   A 1 87  ? 26.61165 -22.95268 16.23623 1.000 50.34745  ? 84  GLU   A HG2  1 
ATOM   1268 H HG3  . GLU   A 1 87  ? 27.44682 -21.70849 16.76529 1.000 50.34745  ? 84  GLU   A HG3  1 
ATOM   1269 N N    . SER   A 1 88  ? 25.70472 -18.88956 13.09294 1.000 28.07352  ? 85  SER   A N    1 
ATOM   1270 C CA   . SER   A 1 88  ? 24.70864 -18.11018 12.36886 1.000 29.42598  ? 85  SER   A CA   1 
ATOM   1271 C C    . SER   A 1 88  ? 24.89444 -18.27882 10.86572 1.000 29.60697  ? 85  SER   A C    1 
ATOM   1272 O O    . SER   A 1 88  ? 25.97419 -18.00298 10.33076 1.000 25.41601  ? 85  SER   A O    1 
ATOM   1273 C CB   . SER   A 1 88  ? 24.80010 -16.63338 12.74787 1.000 27.82204  ? 85  SER   A CB   1 
ATOM   1274 O OG   . SER   A 1 88  ? 23.97339 -15.85355 11.90384 1.000 29.07484  ? 85  SER   A OG   1 
ATOM   1275 H H    . SER   A 1 88  ? 26.43230 -18.46073 13.25525 1.000 33.62259  ? 85  SER   A H    1 
ATOM   1276 H HA   . SER   A 1 88  ? 23.82778 -18.44242 12.60254 1.000 35.24555  ? 85  SER   A HA   1 
ATOM   1277 H HB2  . SER   A 1 88  ? 24.50937 -16.52306 13.66667 1.000 33.32082  ? 85  SER   A HB2  1 
ATOM   1278 H HB3  . SER   A 1 88  ? 25.71908 -16.33781 12.65292 1.000 33.32082  ? 85  SER   A HB3  1 
ATOM   1279 H HG   . SER   A 1 88  ? 24.25853 -15.06407 11.87212 1.000 34.82419  ? 85  SER   A HG   1 
ATOM   1280 N N    . ALA   A 1 89  ? 23.83317 -18.72018 10.18610 1.000 33.62953  ? 86  ALA   A N    1 
ATOM   1281 C CA   . ALA   A 1 89  ? 23.86930 -18.80391 8.73072  1.000 34.20294  ? 86  ALA   A CA   1 
ATOM   1282 C C    . ALA   A 1 89  ? 23.92975 -17.42173 8.09486  1.000 33.32619  ? 86  ALA   A C    1 
ATOM   1283 O O    . ALA   A 1 89  ? 24.54747 -17.25323 7.03739  1.000 30.68129  ? 86  ALA   A O    1 
ATOM   1284 C CB   . ALA   A 1 89  ? 22.64799 -19.56672 8.21829  1.000 37.40508  ? 86  ALA   A CB   1 
ATOM   1285 H H    . ALA   A 1 89  ? 23.09170 -18.97313 10.54083 1.000 40.28981  ? 86  ALA   A H    1 
ATOM   1286 H HA   . ALA   A 1 89  ? 24.66288 -19.29460 8.46547  1.000 40.97790  ? 86  ALA   A HA   1 
ATOM   1287 H HB1  . ALA   A 1 89  ? 22.70282 -19.63849 7.25250  1.000 44.82047  ? 86  ALA   A HB1  1 
ATOM   1288 H HB2  . ALA   A 1 89  ? 22.63864 -20.45151 8.61573  1.000 44.82047  ? 86  ALA   A HB2  1 
ATOM   1289 H HB3  . ALA   A 1 89  ? 21.84546 -19.08299 8.46899  1.000 44.82047  ? 86  ALA   A HB3  1 
ATOM   1290 N N    . ALA   A 1 90  ? 23.29758 -16.42480 8.71900  1.000 28.06065  ? 87  ALA   A N    1 
ATOM   1291 C CA   . ALA   A 1 90  ? 23.36013 -15.06705 8.18903  1.000 29.91994  ? 87  ALA   A CA   1 
ATOM   1292 C C    . ALA   A 1 90  ? 24.79103 -14.54339 8.18879  1.000 31.94730  ? 87  ALA   A C    1 
ATOM   1293 O O    . ALA   A 1 90  ? 25.20377 -13.84066 7.25860  1.000 30.85035  ? 87  ALA   A O    1 
ATOM   1294 C CB   . ALA   A 1 90  ? 22.45048 -14.14545 9.00182  1.000 35.36054  ? 87  ALA   A CB   1 
ATOM   1295 H H    . ALA   A 1 90  ? 22.83407 -16.50856 9.43854  1.000 33.60715  ? 87  ALA   A H    1 
ATOM   1296 H HA   . ALA   A 1 90  ? 23.04101 -15.07204 7.27304  1.000 35.83830  ? 87  ALA   A HA   1 
ATOM   1297 H HB1  . ALA   A 1 90  ? 22.50414 -13.24783 8.63810  1.000 42.36703  ? 87  ALA   A HB1  1 
ATOM   1298 H HB2  . ALA   A 1 90  ? 21.53866 -14.47143 8.94498  1.000 42.36703  ? 87  ALA   A HB2  1 
ATOM   1299 H HB3  . ALA   A 1 90  ? 22.74495 -14.14601 9.92604  1.000 42.36703  ? 87  ALA   A HB3  1 
ATOM   1300 N N    . VAL   A 1 91  ? 25.56468 -14.87382 9.22451  1.000 30.12330  ? 88  VAL   A N    1 
ATOM   1301 C CA   . VAL   A 1 91  ? 26.96196 -14.45578 9.25891  1.000 32.10351  ? 88  VAL   A CA   1 
ATOM   1302 C C    . VAL   A 1 91  ? 27.74631 -15.14335 8.14998  1.000 30.26678  ? 88  VAL   A C    1 
ATOM   1303 O O    . VAL   A 1 91  ? 28.57765 -14.51872 7.48099  1.000 26.09178  ? 88  VAL   A O    1 
ATOM   1304 C CB   . VAL   A 1 91  ? 27.57153 -14.74005 10.64370 1.000 28.76573  ? 88  VAL   A CB   1 
ATOM   1305 C CG1  . VAL   A 1 91  ? 29.06813 -14.46776 10.63407 1.000 30.12873  ? 88  VAL   A CG1  1 
ATOM   1306 C CG2  . VAL   A 1 91  ? 26.88561 -13.89760 11.70860 1.000 31.11831  ? 88  VAL   A CG2  1 
ATOM   1307 H H    . VAL   A 1 91  ? 25.30820 -15.33088 9.90635  1.000 36.08233  ? 88  VAL   A H    1 
ATOM   1308 H HA   . VAL   A 1 91  ? 27.00168 -13.49862 9.10671  1.000 38.45859  ? 88  VAL   A HA   1 
ATOM   1309 H HB   . VAL   A 1 91  ? 27.43477 -15.67577 10.85960 1.000 34.45325  ? 88  VAL   A HB   1 
ATOM   1310 H HG11 . VAL   A 1 91  ? 29.39137 -14.44777 11.54841 1.000 36.08884  ? 88  VAL   A HG11 1 
ATOM   1311 H HG12 . VAL   A 1 91  ? 29.51440 -15.17377 10.14082 1.000 36.08884  ? 88  VAL   A HG12 1 
ATOM   1312 H HG13 . VAL   A 1 91  ? 29.23070 -13.61215 10.20698 1.000 36.08884  ? 88  VAL   A HG13 1 
ATOM   1313 H HG21 . VAL   A 1 91  ? 27.12351 -14.24049 12.58423 1.000 37.27634  ? 88  VAL   A HG21 1 
ATOM   1314 H HG22 . VAL   A 1 91  ? 27.18088 -12.97769 11.62218 1.000 37.27634  ? 88  VAL   A HG22 1 
ATOM   1315 H HG23 . VAL   A 1 91  ? 25.92526 -13.94997 11.58258 1.000 37.27634  ? 88  VAL   A HG23 1 
ATOM   1316 N N    . LYS   A 1 92  ? 27.49491 -16.43751 7.93692  1.000 29.15728  ? 89  LYS   A N    1 
ATOM   1317 C CA   . LYS   A 1 92  ? 28.17387 -17.16395 6.86848  1.000 32.45224  ? 89  LYS   A CA   1 
ATOM   1318 C C    . LYS   A 1 92  ? 27.94612 -16.48634 5.52338  1.000 29.14695  ? 89  LYS   A C    1 
ATOM   1319 O O    . LYS   A 1 92  ? 28.88389 -16.29742 4.74036  1.000 27.57919  ? 89  LYS   A O    1 
ATOM   1320 C CB   . LYS   A 1 92  ? 27.68131 -18.61237 6.83530  1.000 33.25185  ? 89  LYS   A CB   1 
ATOM   1321 C CG   . LYS   A 1 92  ? 28.49407 -19.54238 5.93871  1.000 38.92981  ? 89  LYS   A CG   1 
ATOM   1322 C CD   . LYS   A 1 92  ? 27.83837 -20.92147 5.77877  1.000 45.38802  ? 89  LYS   A CD   1 
ATOM   1323 C CE   . LYS   A 1 92  ? 27.53578 -21.60611 7.11354  1.000 61.47562  ? 89  LYS   A CE   1 
ATOM   1324 N NZ   . LYS   A 1 92  ? 28.75508 -21.95403 7.89516  1.000 48.41659  ? 89  LYS   A NZ   1 
ATOM   1325 H H    . LYS   A 1 92  ? 26.94105 -16.91151 8.39316  1.000 34.92311  ? 89  LYS   A H    1 
ATOM   1326 H HA   . LYS   A 1 92  ? 29.12773 -17.17247 7.04450  1.000 38.87706  ? 89  LYS   A HA   1 
ATOM   1327 H HB2  . LYS   A 1 92  ? 27.71673 -18.97053 7.73606  1.000 39.83659  ? 89  LYS   A HB2  1 
ATOM   1328 H HB3  . LYS   A 1 92  ? 26.76710 -18.61953 6.51115  1.000 39.83659  ? 89  LYS   A HB3  1 
ATOM   1329 H HG2  . LYS   A 1 92  ? 28.57558 -19.14385 5.05813  1.000 46.65014  ? 89  LYS   A HG2  1 
ATOM   1330 H HG3  . LYS   A 1 92  ? 29.37343 -19.67043 6.32760  1.000 46.65014  ? 89  LYS   A HG3  1 
ATOM   1331 H HD2  . LYS   A 1 92  ? 27.00046 -20.81777 5.30122  1.000 54.39999  ? 89  LYS   A HD2  1 
ATOM   1332 H HD3  . LYS   A 1 92  ? 28.43654 -21.49787 5.27793  1.000 54.39999  ? 89  LYS   A HD3  1 
ATOM   1333 H HE2  . LYS   A 1 92  ? 26.99639 -21.00978 7.65608  1.000 73.70512  ? 89  LYS   A HE2  1 
ATOM   1334 H HE3  . LYS   A 1 92  ? 27.05021 -22.42788 6.94089  1.000 73.70512  ? 89  LYS   A HE3  1 
ATOM   1335 H HZ1  . LYS   A 1 92  ? 28.97236 -22.80598 7.75706  1.000 58.03428  ? 89  LYS   A HZ1  1 
ATOM   1336 H HZ2  . LYS   A 1 92  ? 29.43530 -21.43807 7.64379  1.000 58.03428  ? 89  LYS   A HZ2  1 
ATOM   1337 H HZ3  . LYS   A 1 92  ? 28.60511 -21.83134 8.76381  1.000 58.03428  ? 89  LYS   A HZ3  1 
ATOM   1338 N N    . GLU   A 1 93  ? 26.69871 -16.10391 5.24442  1.000 29.14739  ? 90  GLU   A N    1 
ATOM   1339 C CA   . GLU   A 1 93  ? 26.38419 -15.45661 3.97533  1.000 37.31464  ? 90  GLU   A CA   1 
ATOM   1340 C C    . GLU   A 1 93  ? 27.11515 -14.12606 3.83975  1.000 35.36946  ? 90  GLU   A C    1 
ATOM   1341 O O    . GLU   A 1 93  ? 27.67180 -13.81973 2.77851  1.000 29.85268  ? 90  GLU   A O    1 
ATOM   1342 C CB   . GLU   A 1 93  ? 24.87074 -15.26377 3.86464  1.000 45.33403  ? 90  GLU   A CB   1 
ATOM   1343 C CG   . GLU   A 1 93  ? 24.39601 -14.60435 2.58190  1.000 92.47373  ? 90  GLU   A CG   1 
ATOM   1344 C CD   . GLU   A 1 93  ? 22.88674 -14.45066 2.54069  1.000 92.57220  ? 90  GLU   A CD   1 
ATOM   1345 O OE1  . GLU   A 1 93  ? 22.20184 -15.09577 3.36305  1.000 74.80741  ? 90  GLU   A OE1  1 
ATOM   1346 O OE2  . GLU   A 1 93  ? 22.38592 -13.68352 1.69151  1.000 91.38829  ? 90  GLU   A OE2  1 
ATOM   1347 H H    . GLU   A 1 93  ? 26.02442 -16.20716 5.76813  1.000 34.91125  ? 90  GLU   A H    1 
ATOM   1348 H HA   . GLU   A 1 93  ? 26.67182 -16.02451 3.24345  1.000 44.71194  ? 90  GLU   A HA   1 
ATOM   1349 H HB2  . GLU   A 1 93  ? 24.44633 -16.13438 3.91759  1.000 54.33521  ? 90  GLU   A HB2  1 
ATOM   1350 H HB3  . GLU   A 1 93  ? 24.57814 -14.70660 4.60278  1.000 54.33521  ? 90  GLU   A HB3  1 
ATOM   1351 H HG2  . GLU   A 1 93  ? 24.79178 -13.72148 2.51257  1.000 110.90285 ? 90  GLU   A HG2  1 
ATOM   1352 H HG3  . GLU   A 1 93  ? 24.66518 -15.14889 1.82564  1.000 110.90285 ? 90  GLU   A HG3  1 
ATOM   1353 N N    . ILE   A 1 94  ? 27.13312 -13.32524 4.90784  1.000 32.13616  ? 91  ILE   A N    1 
ATOM   1354 C CA   . ILE   A 1 94  ? 27.79173 -12.02276 4.84980  1.000 32.91144  ? 91  ILE   A CA   1 
ATOM   1355 C C    . ILE   A 1 94  ? 29.28881 -12.18835 4.62605  1.000 28.26916  ? 91  ILE   A C    1 
ATOM   1356 O O    . ILE   A 1 94  ? 29.89759 -11.45918 3.83346  1.000 32.30957  ? 91  ILE   A O    1 
ATOM   1357 C CB   . ILE   A 1 94  ? 27.50239 -11.22037 6.13243  1.000 34.20875  ? 91  ILE   A CB   1 
ATOM   1358 C CG1  . ILE   A 1 94  ? 26.04579 -10.75338 6.15153  1.000 47.80767  ? 91  ILE   A CG1  1 
ATOM   1359 C CG2  . ILE   A 1 94  ? 28.45238 -10.03462 6.24193  1.000 35.19731  ? 91  ILE   A CG2  1 
ATOM   1360 C CD1  . ILE   A 1 94  ? 25.58185 -10.25825 7.50362  1.000 46.72670  ? 91  ILE   A CD1  1 
ATOM   1361 H H    . ILE   A 1 94  ? 26.77568 -13.51106 5.66764  1.000 38.49776  ? 91  ILE   A H    1 
ATOM   1362 H HA   . ILE   A 1 94  ? 27.42898 -11.53160 4.09609  1.000 39.42810  ? 91  ILE   A HA   1 
ATOM   1363 H HB   . ILE   A 1 94  ? 27.64629 -11.79941 6.89722  1.000 40.98487  ? 91  ILE   A HB   1 
ATOM   1364 H HG12 . ILE   A 1 94  ? 25.94338 -10.02544 5.51866  1.000 57.30358  ? 91  ILE   A HG12 1 
ATOM   1365 H HG13 . ILE   A 1 94  ? 25.47669 -11.49659 5.89725  1.000 57.30358  ? 91  ILE   A HG13 1 
ATOM   1366 H HG21 . ILE   A 1 94  ? 28.07931 -9.38714  6.86039  1.000 42.17114  ? 91  ILE   A HG21 1 
ATOM   1367 H HG22 . ILE   A 1 94  ? 29.31093 -10.34687 6.56793  1.000 42.17114  ? 91  ILE   A HG22 1 
ATOM   1368 H HG23 . ILE   A 1 94  ? 28.55771 -9.63238  5.36557  1.000 42.17114  ? 91  ILE   A HG23 1 
ATOM   1369 H HD11 . ILE   A 1 94  ? 24.62161 -10.12344 7.47811  1.000 56.00642  ? 91  ILE   A HD11 1 
ATOM   1370 H HD12 . ILE   A 1 94  ? 25.80512 -10.92066 8.17613  1.000 56.00642  ? 91  ILE   A HD12 1 
ATOM   1371 H HD13 . ILE   A 1 94  ? 26.02829 -9.42058  7.70339  1.000 56.00642  ? 91  ILE   A HD13 1 
ATOM   1372 N N    . LEU   A 1 95  ? 29.90847 -13.14369 5.32278  1.000 26.37346  ? 92  LEU   A N    1 
ATOM   1373 C CA   . LEU   A 1 95  ? 31.35556 -13.30075 5.22188  1.000 29.84101  ? 92  LEU   A CA   1 
ATOM   1374 C C    . LEU   A 1 95  ? 31.76075 -13.83875 3.85421  1.000 29.77274  ? 92  LEU   A C    1 
ATOM   1375 O O    . LEU   A 1 95  ? 32.72111 -13.34664 3.25016  1.000 26.65082  ? 92  LEU   A O    1 
ATOM   1376 C CB   . LEU   A 1 95  ? 31.86467 -14.21362 6.33781  1.000 31.19235  ? 92  LEU   A CB   1 
ATOM   1377 C CG   . LEU   A 1 95  ? 31.73537 -13.65596 7.75912  1.000 33.67742  ? 92  LEU   A CG   1 
ATOM   1378 C CD1  . LEU   A 1 95  ? 32.12707 -14.70672 8.78359  1.000 28.42784  ? 92  LEU   A CD1  1 
ATOM   1379 C CD2  . LEU   A 1 95  ? 32.57980 -12.39978 7.94124  1.000 31.22495  ? 92  LEU   A CD2  1 
ATOM   1380 H H    A LEU   A 1 95  ? 29.52056 -13.70168 5.84982  0.650 31.58253  ? 92  LEU   A H    1 
ATOM   1381 H H    B LEU   A 1 95  ? 29.52056 -13.70168 5.84982  0.350 31.58253  ? 92  LEU   A H    1 
ATOM   1382 H HA   . LEU   A 1 95  ? 31.77259 -12.43231 5.33497  1.000 35.74359  ? 92  LEU   A HA   1 
ATOM   1383 H HB2  . LEU   A 1 95  ? 31.36194 -15.04255 6.30570  1.000 37.36520  ? 92  LEU   A HB2  1 
ATOM   1384 H HB3  . LEU   A 1 95  ? 32.80553 -14.38994 6.18097  1.000 37.36520  ? 92  LEU   A HB3  1 
ATOM   1385 H HG   . LEU   A 1 95  ? 30.80813 -13.41256 7.90703  1.000 40.34728  ? 92  LEU   A HG   1 
ATOM   1386 H HD11 . LEU   A 1 95  ? 32.01887 -14.33600 9.67340  1.000 34.04778  ? 92  LEU   A HD11 1 
ATOM   1387 H HD12 . LEU   A 1 95  ? 31.55370 -15.48170 8.67616  1.000 34.04778  ? 92  LEU   A HD12 1 
ATOM   1388 H HD13 . LEU   A 1 95  ? 33.05296 -14.95785 8.64022  1.000 34.04778  ? 92  LEU   A HD13 1 
ATOM   1389 H HD21 . LEU   A 1 95  ? 32.57106 -12.14638 8.87752  1.000 37.40431  ? 92  LEU   A HD21 1 
ATOM   1390 H HD22 . LEU   A 1 95  ? 33.48845 -12.58619 7.65748  1.000 37.40431  ? 92  LEU   A HD22 1 
ATOM   1391 H HD23 . LEU   A 1 95  ? 32.20466 -11.68614 7.40190  1.000 37.40431  ? 92  LEU   A HD23 1 
ATOM   1392 N N    A LYS   A 1 96  ? 31.04123 -14.84298 3.34636  0.460 32.53099  ? 93  LYS   A N    1 
ATOM   1393 N N    B LYS   A 1 96  ? 31.04936 -14.85073 3.34977  0.540 32.57387  ? 93  LYS   A N    1 
ATOM   1394 C CA   A LYS   A 1 96  ? 31.36326 -15.37941 2.02735  0.460 32.23889  ? 93  LYS   A CA   1 
ATOM   1395 C CA   B LYS   A 1 96  ? 31.36996 -15.37421 2.02501  0.540 32.18508  ? 93  LYS   A CA   1 
ATOM   1396 C C    A LYS   A 1 96  ? 31.21820 -14.31045 0.95132  0.460 32.87995  ? 93  LYS   A C    1 
ATOM   1397 C C    B LYS   A 1 96  ? 31.23320 -14.29063 0.96405  0.540 32.83809  ? 93  LYS   A C    1 
ATOM   1398 O O    A LYS   A 1 96  ? 32.06125 -14.20517 0.05263  0.460 34.83231  ? 93  LYS   A O    1 
ATOM   1399 O O    B LYS   A 1 96  ? 32.09571 -14.15622 0.08817  0.540 34.66253  ? 93  LYS   A O    1 
ATOM   1400 C CB   A LYS   A 1 96  ? 30.47593 -16.58578 1.71813  0.460 35.56982  ? 93  LYS   A CB   1 
ATOM   1401 C CB   B LYS   A 1 96  ? 30.47524 -16.56896 1.69096  0.540 35.50913  ? 93  LYS   A CB   1 
ATOM   1402 C CG   A LYS   A 1 96  ? 30.78365 -17.80556 2.57838  0.460 44.00840  ? 93  LYS   A CG   1 
ATOM   1403 C CG   B LYS   A 1 96  ? 31.02171 -17.91670 2.15867  0.540 43.65324  ? 93  LYS   A CG   1 
ATOM   1404 C CD   A LYS   A 1 96  ? 30.05398 -19.04826 2.08930  0.460 49.48970  ? 93  LYS   A CD   1 
ATOM   1405 C CD   B LYS   A 1 96  ? 32.29214 -18.30883 1.40659  0.540 50.24425  ? 93  LYS   A CD   1 
ATOM   1406 C CE   A LYS   A 1 96  ? 30.44363 -20.27773 2.90043  0.460 53.43592  ? 93  LYS   A CE   1 
ATOM   1407 C CE   B LYS   A 1 96  ? 32.91869 -19.57357 1.97650  0.540 41.26251  ? 93  LYS   A CE   1 
ATOM   1408 N NZ   A LYS   A 1 96  ? 31.88380 -20.62902 2.74498  0.460 41.96863  ? 93  LYS   A NZ   1 
ATOM   1409 N NZ   B LYS   A 1 96  ? 34.31996 -19.76147 1.49975  0.540 41.22605  ? 93  LYS   A NZ   1 
ATOM   1410 H H    A LYS   A 1 96  ? 30.37614 -15.22220 3.73807  0.460 38.97156  ? 93  LYS   A H    1 
ATOM   1411 H H    B LYS   A 1 96  ? 30.39304 -15.24091 3.74550  0.540 39.02301  ? 93  LYS   A H    1 
ATOM   1412 H HA   A LYS   A 1 96  ? 32.28473 -15.68240 2.02700  0.460 38.62104  ? 93  LYS   A HA   1 
ATOM   1413 H HA   B LYS   A 1 96  ? 32.28849 -15.68597 2.02745  0.540 38.55647  ? 93  LYS   A HA   1 
ATOM   1414 H HB2  A LYS   A 1 96  ? 29.55016 -16.34021 1.87156  0.460 42.61816  ? 93  LYS   A HB2  1 
ATOM   1415 H HB2  B LYS   A 1 96  ? 29.61325 -16.43831 2.11616  0.540 42.54533  ? 93  LYS   A HB2  1 
ATOM   1416 H HB3  A LYS   A 1 96  ? 30.60299 -16.83738 0.78999  0.460 42.61816  ? 93  LYS   A HB3  1 
ATOM   1417 H HB3  B LYS   A 1 96  ? 30.36673 -16.61449 0.72813  0.540 42.54533  ? 93  LYS   A HB3  1 
ATOM   1418 H HG2  A LYS   A 1 96  ? 31.73674 -17.98368 2.55040  0.460 52.74446  ? 93  LYS   A HG2  1 
ATOM   1419 H HG2  B LYS   A 1 96  ? 31.23275 -17.86546 3.10405  0.540 52.31826  ? 93  LYS   A HG2  1 
ATOM   1420 H HG3  A LYS   A 1 96  ? 30.50544 -17.63091 3.49106  0.460 52.74446  ? 93  LYS   A HG3  1 
ATOM   1421 H HG3  B LYS   A 1 96  ? 30.35409 -18.60330 2.00452  0.540 52.31826  ? 93  LYS   A HG3  1 
ATOM   1422 H HD2  A LYS   A 1 96  ? 29.09723 -18.91507 2.17756  0.460 59.32202  ? 93  LYS   A HD2  1 
ATOM   1423 H HD2  B LYS   A 1 96  ? 32.07571 -18.47046 0.47496  0.540 60.22747  ? 93  LYS   A HD2  1 
ATOM   1424 H HD3  A LYS   A 1 96  ? 30.28207 -19.21051 1.16056  0.460 59.32202  ? 93  LYS   A HD3  1 
ATOM   1425 H HD3  B LYS   A 1 96  ? 32.94036 -17.59066 1.47683  0.540 60.22747  ? 93  LYS   A HD3  1 
ATOM   1426 H HE2  A LYS   A 1 96  ? 30.27571 -20.10458 3.83996  0.460 64.05748  ? 93  LYS   A HE2  1 
ATOM   1427 H HE2  B LYS   A 1 96  ? 32.93248 -19.51551 2.94466  0.540 49.44939  ? 93  LYS   A HE2  1 
ATOM   1428 H HE3  A LYS   A 1 96  ? 29.91527 -21.03488 2.60301  0.460 64.05748  ? 93  LYS   A HE3  1 
ATOM   1429 H HE3  B LYS   A 1 96  ? 32.39732 -20.34254 1.69766  0.540 49.44939  ? 93  LYS   A HE3  1 
ATOM   1430 H HZ1  A LYS   A 1 96  ? 32.06563 -20.79685 1.89007  0.460 50.29673  ? 93  LYS   A HZ1  1 
ATOM   1431 H HZ1  B LYS   A 1 96  ? 34.82175 -19.07014 1.74949  0.540 49.40563  ? 93  LYS   A HZ1  1 
ATOM   1432 H HZ2  A LYS   A 1 96  ? 32.07472 -21.35166 3.22814  0.460 50.29673  ? 93  LYS   A HZ2  1 
ATOM   1433 H HZ2  B LYS   A 1 96  ? 34.66196 -20.50662 1.84600  0.540 49.40563  ? 93  LYS   A HZ2  1 
ATOM   1434 H HZ3  A LYS   A 1 96  ? 32.39339 -19.95378 3.02150  0.460 50.29673  ? 93  LYS   A HZ3  1 
ATOM   1435 H HZ3  B LYS   A 1 96  ? 34.33382 -19.82266 0.61196  0.540 49.40563  ? 93  LYS   A HZ3  1 
ATOM   1436 N N    . GLU   A 1 97  ? 30.15983 -13.50183 1.02897  1.000 32.47015  ? 94  GLU   A N    1 
ATOM   1437 C CA   . GLU   A 1 97  ? 30.00585 -12.39379 0.09336  1.000 36.54912  ? 94  GLU   A CA   1 
ATOM   1438 C C    . GLU   A 1 97  ? 31.17399 -11.42256 0.20768  1.000 38.11217  ? 94  GLU   A C    1 
ATOM   1439 O O    . GLU   A 1 97  ? 31.73032 -10.98369 -0.80448 1.000 29.42189  ? 94  GLU   A O    1 
ATOM   1440 C CB   . GLU   A 1 97  ? 28.67963 -11.67489 0.34427  1.000 38.57197  ? 94  GLU   A CB   1 
ATOM   1441 C CG   . GLU   A 1 97  ? 28.51968 -10.35477 -0.40388 1.000 60.91758  ? 94  GLU   A CG   1 
ATOM   1442 C CD   . GLU   A 1 97  ? 27.26895 -9.60304  0.00849  1.000 80.20680  ? 94  GLU   A CD   1 
ATOM   1443 O OE1  . GLU   A 1 97  ? 26.36128 -10.23123 0.59334  1.000 80.68351  ? 94  GLU   A OE1  1 
ATOM   1444 O OE2  . GLU   A 1 97  ? 27.19786 -8.38227  -0.24491 1.000 92.43865  ? 94  GLU   A OE2  1 
ATOM   1445 H H    A GLU   A 1 97  ? 29.52671 -13.57364 1.60655  0.460 38.89855  ? 94  GLU   A H    1 
ATOM   1446 H H    B GLU   A 1 97  ? 29.51863 -13.58657 1.59578  0.540 38.89855  ? 94  GLU   A H    1 
ATOM   1447 H HA   . GLU   A 1 97  ? 29.98913 -12.74510 -0.81063 1.000 43.79332  ? 94  GLU   A HA   1 
ATOM   1448 H HB2  . GLU   A 1 97  ? 27.95567 -12.25776 0.06668  1.000 46.22074  ? 94  GLU   A HB2  1 
ATOM   1449 H HB3  . GLU   A 1 97  ? 28.60695 -11.48412 1.29254  1.000 46.22074  ? 94  GLU   A HB3  1 
ATOM   1450 H HG2  . GLU   A 1 97  ? 29.28583 -9.78976  -0.21768 1.000 73.03546  ? 94  GLU   A HG2  1 
ATOM   1451 H HG3  . GLU   A 1 97  ? 28.46326 -10.53423 -1.35546 1.000 73.03546  ? 94  GLU   A HG3  1 
ATOM   1452 N N    . GLN   A 1 98  ? 31.55974 -11.07467 1.43985  1.000 31.32962  ? 95  GLN   A N    1 
ATOM   1453 C CA   . GLN   A 1 98  ? 32.66806 -10.14380 1.63290  1.000 32.79993  ? 95  GLN   A CA   1 
ATOM   1454 C C    . GLN   A 1 98  ? 33.96348 -10.71261 1.06827  1.000 32.50217  ? 95  GLN   A C    1 
ATOM   1455 O O    . GLN   A 1 98  ? 34.77245 -9.98007  0.48625  1.000 30.56274  ? 95  GLN   A O    1 
ATOM   1456 C CB   . GLN   A 1 98  ? 32.82384 -9.82096  3.12055  1.000 28.77708  ? 95  GLN   A CB   1 
ATOM   1457 C CG   . GLN   A 1 98  ? 33.86028 -8.74713  3.43529  1.000 32.01484  ? 95  GLN   A CG   1 
ATOM   1458 C CD   . GLN   A 1 98  ? 33.39946 -7.35050  3.05846  1.000 36.36509  ? 95  GLN   A CD   1 
ATOM   1459 O OE1  . GLN   A 1 98  ? 32.38921 -7.17886  2.37721  1.000 32.05639  ? 95  GLN   A OE1  1 
ATOM   1460 N NE2  . GLN   A 1 98  ? 34.13848 -6.34263  3.50944  1.000 29.72239  ? 95  GLN   A NE2  1 
ATOM   1461 H H    . GLN   A 1 98  ? 31.20074 -11.35997 2.16740  1.000 37.52992  ? 95  GLN   A H    1 
ATOM   1462 H HA   . GLN   A 1 98  ? 32.47307 -9.31685  1.16490  1.000 39.29429  ? 95  GLN   A HA   1 
ATOM   1463 H HB2  . GLN   A 1 98  ? 31.96963 -9.51055  3.45948  1.000 34.46687  ? 95  GLN   A HB2  1 
ATOM   1464 H HB3  . GLN   A 1 98  ? 33.09097 -10.62961 3.58491  1.000 34.46687  ? 95  GLN   A HB3  1 
ATOM   1465 H HG2  . GLN   A 1 98  ? 34.04303 -8.75488  4.38789  1.000 38.35219  ? 95  GLN   A HG2  1 
ATOM   1466 H HG3  . GLN   A 1 98  ? 34.67228 -8.93788  2.94014  1.000 38.35219  ? 95  GLN   A HG3  1 
ATOM   1467 H HE21 . GLN   A 1 98  ? 34.83576 -6.50087  3.98732  1.000 35.60124  ? 95  GLN   A HE21 1 
ATOM   1468 H HE22 . GLN   A 1 98  ? 33.91955 -5.53202  3.32347  1.000 35.60124  ? 95  GLN   A HE22 1 
ATOM   1469 N N    . GLU   A 1 99  ? 34.17657 -12.01979 1.22871  1.000 28.60707  ? 96  GLU   A N    1 
ATOM   1470 C CA   . GLU   A 1 99  ? 35.37282 -12.64498 0.67642  1.000 38.46097  ? 96  GLU   A CA   1 
ATOM   1471 C C    . GLU   A 1 99  ? 35.36070 -12.60526 -0.84718 1.000 35.64440  ? 96  GLU   A C    1 
ATOM   1472 O O    . GLU   A 1 99  ? 36.38881 -12.32318 -1.47356 1.000 39.35782  ? 96  GLU   A O    1 
ATOM   1473 C CB   . GLU   A 1 99  ? 35.48378 -14.08614 1.17508  1.000 38.17430  ? 96  GLU   A CB   1 
ATOM   1474 C CG   . GLU   A 1 99  ? 36.83045 -14.73966 0.90248  1.000 43.46156  ? 96  GLU   A CG   1 
ATOM   1475 C CD   . GLU   A 1 99  ? 36.89653 -16.16980 1.40630  1.000 35.91944  ? 96  GLU   A CD   1 
ATOM   1476 O OE1  . GLU   A 1 99  ? 35.85488 -16.86086 1.38905  1.000 44.22327  ? 96  GLU   A OE1  1 
ATOM   1477 O OE2  . GLU   A 1 99  ? 37.99043 -16.60043 1.82567  1.000 41.64626  ? 96  GLU   A OE2  1 
ATOM   1478 H H    . GLU   A 1 99  ? 33.65133 -12.55722 1.64692  1.000 34.26286  ? 96  GLU   A H    1 
ATOM   1479 H HA   . GLU   A 1 99  ? 36.15348 -12.15811 0.98372  1.000 46.08753  ? 96  GLU   A HA   1 
ATOM   1480 H HB2  . GLU   A 1 99  ? 35.34206 -14.09383 2.13464  1.000 45.74353  ? 96  GLU   A HB2  1 
ATOM   1481 H HB3  . GLU   A 1 99  ? 34.80360 -14.61958 0.73498  1.000 45.74353  ? 96  GLU   A HB3  1 
ATOM   1482 H HG2  . GLU   A 1 99  ? 36.98960 -14.75022 -0.05432 1.000 52.08824  ? 96  GLU   A HG2  1 
ATOM   1483 H HG3  . GLU   A 1 99  ? 37.52552 -14.23116 1.34881  1.000 52.08824  ? 96  GLU   A HG3  1 
ATOM   1484 N N    . ASN   A 1 100 ? 34.20419 -12.87370 -1.46058 1.000 36.10521  ? 97  ASN   A N    1 
ATOM   1485 C CA   . ASN   A 1 100 ? 34.13493 -12.91702 -2.91805 1.000 47.25044  ? 97  ASN   A CA   1 
ATOM   1486 C C    . ASN   A 1 100 ? 34.43864 -11.55590 -3.53034 1.000 46.18395  ? 97  ASN   A C    1 
ATOM   1487 O O    . ASN   A 1 100 ? 35.17373 -11.46503 -4.52041 1.000 45.36751  ? 97  ASN   A O    1 
ATOM   1488 C CB   . ASN   A 1 100 ? 32.75909 -13.40840 -3.36795 1.000 47.84104  ? 97  ASN   A CB   1 
ATOM   1489 C CG   . ASN   A 1 100 ? 32.57301 -14.89846 -3.15351 1.000 68.70600  ? 97  ASN   A CG   1 
ATOM   1490 O OD1  . ASN   A 1 100 ? 33.54046 -15.65979 -3.12407 1.000 85.70627  ? 97  ASN   A OD1  1 
ATOM   1491 N ND2  . ASN   A 1 100 ? 31.32286 -15.32347 -3.00897 1.000 70.52356  ? 97  ASN   A ND2  1 
ATOM   1492 H H    . ASN   A 1 100 ? 33.45915 -13.03140 -1.06102 1.000 43.26063  ? 97  ASN   A H    1 
ATOM   1493 H HA   . ASN   A 1 100 ? 34.79966 -13.54649 -3.23869 1.000 56.63490  ? 97  ASN   A HA   1 
ATOM   1494 H HB2  . ASN   A 1 100 ? 32.07540 -12.94401 -2.86020 1.000 57.34363  ? 97  ASN   A HB2  1 
ATOM   1495 H HB3  . ASN   A 1 100 ? 32.65134 -13.22521 -4.31438 1.000 57.34363  ? 97  ASN   A HB3  1 
ATOM   1496 H HD21 . ASN   A 1 100 ? 31.16459 -16.15963 -2.88489 1.000 84.56264  ? 97  ASN   A HD21 1 
ATOM   1497 H HD22 . ASN   A 1 100 ? 30.67173 -14.76249 -3.03947 1.000 84.56264  ? 97  ASN   A HD22 1 
ATOM   1498 N N    . ARG   A 1 101 ? 33.88193 -10.48685 -2.96403 1.000 36.33937  ? 98  ARG   A N    1 
ATOM   1499 C CA   . ARG   A 1 101 ? 34.14512 -9.14353  -3.46438 1.000 33.67516  ? 98  ARG   A CA   1 
ATOM   1500 C C    . ARG   A 1 101 ? 35.44292 -8.56248  -2.92084 1.000 39.77748  ? 98  ARG   A C    1 
ATOM   1501 O O    . ARG   A 1 101 ? 35.69666 -7.36691  -3.10500 1.000 42.60228  ? 98  ARG   A O    1 
ATOM   1502 C CB   . ARG   A 1 101 ? 32.97333 -8.21350  -3.13757 1.000 43.80628  ? 98  ARG   A CB   1 
ATOM   1503 C CG   . ARG   A 1 101 ? 32.71408 -7.99954  -1.65995 1.000 52.03403  ? 98  ARG   A CG   1 
ATOM   1504 C CD   . ARG   A 1 101 ? 31.54272 -7.05289  -1.45457 1.000 58.70957  ? 98  ARG   A CD   1 
ATOM   1505 N NE   . ARG   A 1 101 ? 31.83228 -5.72816  -1.98976 1.000 63.89056  ? 98  ARG   A NE   1 
ATOM   1506 C CZ   . ARG   A 1 101 ? 32.47894 -4.77683  -1.32903 1.000 95.57961  ? 98  ARG   A CZ   1 
ATOM   1507 N NH1  . ARG   A 1 101 ? 32.89804 -4.95876  -0.08632 1.000 49.97204  ? 98  ARG   A NH1  1 
ATOM   1508 N NH2  . ARG   A 1 101 ? 32.71430 -3.61453  -1.93153 1.000 80.34469  ? 98  ARG   A NH2  1 
ATOM   1509 H H    A ARG   A 1 101 ? 33.34910 -10.51596 -2.28961 0.410 43.54162  ? 98  ARG   A H    1 
ATOM   1510 H H    B ARG   A 1 101 ? 33.34910 -10.51596 -2.28961 0.590 43.54162  ? 98  ARG   A H    1 
ATOM   1511 H HA   . ARG   A 1 101 ? 34.21965 -9.18339  -4.43069 1.000 40.34457  ? 98  ARG   A HA   1 
ATOM   1512 H HB2  . ARG   A 1 101 ? 33.15320 -7.34462  -3.52948 1.000 52.50191  ? 98  ARG   A HB2  1 
ATOM   1513 H HB3  . ARG   A 1 101 ? 32.16652 -8.59034  -3.52222 1.000 52.50191  ? 98  ARG   A HB3  1 
ATOM   1514 H HG2  . ARG   A 1 101 ? 32.50210 -8.84840  -1.24113 1.000 62.37521  ? 98  ARG   A HG2  1 
ATOM   1515 H HG3  . ARG   A 1 101 ? 33.50056 -7.61209  -1.24496 1.000 62.37521  ? 98  ARG   A HG3  1 
ATOM   1516 H HD2  . ARG   A 1 101 ? 30.76186 -7.40327  -1.91108 1.000 70.38586  ? 98  ARG   A HD2  1 
ATOM   1517 H HD3  . ARG   A 1 101 ? 31.36128 -6.96649  -0.50561 1.000 70.38586  ? 98  ARG   A HD3  1 
ATOM   1518 H HE   . ARG   A 1 101 ? 31.56576 -5.55139  -2.78808 1.000 76.60304  ? 98  ARG   A HE   1 
ATOM   1519 H HH11 . ARG   A 1 101 ? 32.75286 -5.70744  0.31118  1.000 59.90082  ? 98  ARG   A HH11 1 
ATOM   1520 H HH12 . ARG   A 1 101 ? 33.31543 -4.32824  0.32336  1.000 59.90082  ? 98  ARG   A HH12 1 
ATOM   1521 H HH21 . ARG   A 1 101 ? 32.44816 -3.48728  -2.73935 1.000 96.34801  ? 98  ARG   A HH21 1 
ATOM   1522 H HH22 . ARG   A 1 101 ? 33.13260 -2.99030  -1.51324 1.000 96.34801  ? 98  ARG   A HH22 1 
ATOM   1523 N N    . LYS   A 1 102 ? 36.26130 -9.38210  -2.25967 1.000 41.16278  ? 99  LYS   A N    1 
ATOM   1524 C CA   . LYS   A 1 102 ? 37.59471 -8.97826  -1.81530 1.000 42.97592  ? 99  LYS   A CA   1 
ATOM   1525 C C    . LYS   A 1 102 ? 37.52739 -7.78328  -0.86802 1.000 43.64504  ? 99  LYS   A C    1 
ATOM   1526 O O    . LYS   A 1 102 ? 38.36824 -6.88298  -0.90867 1.000 39.25541  ? 99  LYS   A O    1 
ATOM   1527 C CB   . LYS   A 1 102 ? 38.49815 -8.68523  -3.01553 1.000 45.63548  ? 99  LYS   A CB   1 
ATOM   1528 C CG   . LYS   A 1 102 ? 38.79063 -9.92605  -3.85444 1.000 57.89361  ? 99  LYS   A CG   1 
ATOM   1529 C CD   . LYS   A 1 102 ? 39.32657 -9.58175  -5.23505 1.000 97.00297  ? 99  LYS   A CD   1 
ATOM   1530 C CE   . LYS   A 1 102 ? 40.82946 -9.36227  -5.22436 1.000 96.29556  ? 99  LYS   A CE   1 
ATOM   1531 N NZ   . LYS   A 1 102 ? 41.31121 -8.82061  -6.52527 1.000 107.10591 ? 99  LYS   A NZ   1 
ATOM   1532 H H    . LYS   A 1 102 ? 36.06273 -10.19287 -2.05270 1.000 49.32971  ? 99  LYS   A H    1 
ATOM   1533 H HA   . LYS   A 1 102 ? 37.98989 -9.70950  -1.31528 1.000 51.50547  ? 99  LYS   A HA   1 
ATOM   1534 H HB2  . LYS   A 1 102 ? 38.06242 -8.03314  -3.58632 1.000 54.69695  ? 99  LYS   A HB2  1 
ATOM   1535 H HB3  . LYS   A 1 102 ? 39.34355 -8.33355  -2.69533 1.000 54.69695  ? 99  LYS   A HB3  1 
ATOM   1536 H HG2  . LYS   A 1 102 ? 39.45542 -10.46698 -3.40018 1.000 69.40671  ? 99  LYS   A HG2  1 
ATOM   1537 H HG3  . LYS   A 1 102 ? 37.97147 -10.43303 -3.96777 1.000 69.40671  ? 99  LYS   A HG3  1 
ATOM   1538 H HD2  . LYS   A 1 102 ? 39.13158 -10.31098 -5.84423 1.000 116.33794 ? 99  LYS   A HD2  1 
ATOM   1539 H HD3  . LYS   A 1 102 ? 38.90391 -8.76648  -5.54743 1.000 116.33794 ? 99  LYS   A HD3  1 
ATOM   1540 H HE2  . LYS   A 1 102 ? 41.05633 -8.72751  -4.52686 1.000 115.48904 ? 99  LYS   A HE2  1 
ATOM   1541 H HE3  . LYS   A 1 102 ? 41.27631 -10.20770 -5.06169 1.000 115.48904 ? 99  LYS   A HE3  1 
ATOM   1542 H HZ1  . LYS   A 1 102 ? 42.20020 -8.77819  -6.52687 1.000 128.46146 ? 99  LYS   A HZ1  1 
ATOM   1543 H HZ2  . LYS   A 1 102 ? 41.04601 -9.34784  -7.19146 1.000 128.46146 ? 99  LYS   A HZ2  1 
ATOM   1544 H HZ3  . LYS   A 1 102 ? 40.98283 -8.00368  -6.65520 1.000 128.46146 ? 99  LYS   A HZ3  1 
ATOM   1545 N N    . GLY   A 1 103 ? 36.51295 -7.77710  -0.00431 1.000 34.77664  ? 100 GLY   A N    1 
ATOM   1546 C CA   . GLY   A 1 103 ? 36.43495 -6.79359  1.04974  1.000 35.43599  ? 100 GLY   A CA   1 
ATOM   1547 C C    . GLY   A 1 103 ? 37.16656 -7.23932  2.30332  1.000 30.28368  ? 100 GLY   A C    1 
ATOM   1548 O O    . GLY   A 1 103 ? 37.45413 -8.41866  2.49452  1.000 30.59321  ? 100 GLY   A O    1 
ATOM   1549 H H    . GLY   A 1 103 ? 35.85997 -8.33667  -0.01453 1.000 41.66634  ? 100 GLY   A H    1 
ATOM   1550 H HA2  . GLY   A 1 103 ? 36.82914 -5.96181  0.74370  1.000 42.45756  ? 100 GLY   A HA2  1 
ATOM   1551 H HA3  . GLY   A 1 103 ? 35.50476 -6.63768  1.27632  1.000 42.45756  ? 100 GLY   A HA3  1 
ATOM   1552 N N    . LEU   A 1 104 ? 37.46457 -6.27126  3.16425  1.000 28.42369  ? 101 LEU   A N    1 
ATOM   1553 C CA   . LEU   A 1 104 ? 38.23499 -6.55311  4.36699  1.000 24.96673  ? 101 LEU   A CA   1 
ATOM   1554 C C    . LEU   A 1 104 ? 37.37959 -7.26958  5.40490  1.000 25.87764  ? 101 LEU   A C    1 
ATOM   1555 O O    . LEU   A 1 104 ? 36.19747 -6.96325  5.58511  1.000 21.69619  ? 101 LEU   A O    1 
ATOM   1556 C CB   . LEU   A 1 104 ? 38.79114 -5.25440  4.94961  1.000 32.37819  ? 101 LEU   A CB   1 
ATOM   1557 C CG   . LEU   A 1 104 ? 39.71728 -5.36699  6.16231  1.000 45.66223  ? 101 LEU   A CG   1 
ATOM   1558 C CD1  . LEU   A 1 104 ? 40.91218 -6.25609  5.85701  1.000 37.15006  ? 101 LEU   A CD1  1 
ATOM   1559 C CD2  . LEU   A 1 104 ? 40.17663 -3.98327  6.59845  1.000 42.19743  ? 101 LEU   A CD2  1 
ATOM   1560 H H    . LEU   A 1 104 ? 37.23337 -5.44777  3.07477  1.000 34.04280  ? 101 LEU   A H    1 
ATOM   1561 H HA   . LEU   A 1 104 ? 38.97971 -7.13272  4.14262  1.000 29.89445  ? 101 LEU   A HA   1 
ATOM   1562 H HB2  . LEU   A 1 104 ? 39.29501 -4.80757  4.25150  1.000 38.78820  ? 101 LEU   A HB2  1 
ATOM   1563 H HB3  . LEU   A 1 104 ? 38.03934 -4.70435  5.22003  1.000 38.78820  ? 101 LEU   A HB3  1 
ATOM   1564 H HG   . LEU   A 1 104 ? 39.22944 -5.77545  6.89449  1.000 54.72905  ? 101 LEU   A HG   1 
ATOM   1565 H HD11 . LEU   A 1 104 ? 41.66804 -5.96320  6.38973  1.000 44.51444  ? 101 LEU   A HD11 1 
ATOM   1566 H HD12 . LEU   A 1 104 ? 40.68769 -7.17359  6.07769  1.000 44.51444  ? 101 LEU   A HD12 1 
ATOM   1567 H HD13 . LEU   A 1 104 ? 41.12540 -6.18552  4.91337  1.000 44.51444  ? 101 LEU   A HD13 1 
ATOM   1568 H HD21 . LEU   A 1 104 ? 40.70708 -4.06666  7.40626  1.000 50.57129  ? 101 LEU   A HD21 1 
ATOM   1569 H HD22 . LEU   A 1 104 ? 40.71120 -3.59037  5.89080  1.000 50.57129  ? 101 LEU   A HD22 1 
ATOM   1570 H HD23 . LEU   A 1 104 ? 39.39758 -3.43134  6.76979  1.000 50.57129  ? 101 LEU   A HD23 1 
ATOM   1571 N N    . ILE   A 1 105 ? 37.98813 -8.23629  6.08610  1.000 26.60471  ? 102 ILE   A N    1 
ATOM   1572 C CA   . ILE   A 1 105 ? 37.35970 -8.95722  7.18590  1.000 27.03612  ? 102 ILE   A CA   1 
ATOM   1573 C C    . ILE   A 1 105 ? 38.27914 -8.85137  8.39293  1.000 27.20719  ? 102 ILE   A C    1 
ATOM   1574 O O    . ILE   A 1 105 ? 39.47445 -9.15170  8.29466  1.000 25.00925  ? 102 ILE   A O    1 
ATOM   1575 C CB   . ILE   A 1 105 ? 37.09127 -10.43164 6.82885  1.000 24.73700  ? 102 ILE   A CB   1 
ATOM   1576 C CG1  . ILE   A 1 105 ? 36.10022 -10.51408 5.66362  1.000 29.69139  ? 102 ILE   A CG1  1 
ATOM   1577 C CG2  . ILE   A 1 105 ? 36.56848 -11.18530 8.04744  1.000 28.57982  ? 102 ILE   A CG2  1 
ATOM   1578 C CD1  . ILE   A 1 105 ? 35.89656 -11.91467 5.11241  1.000 33.93464  ? 102 ILE   A CD1  1 
ATOM   1579 H H    . ILE   A 1 105 ? 38.79053 -8.49954  5.92345  1.000 31.86003  ? 102 ILE   A H    1 
ATOM   1580 H HA   . ILE   A 1 105 ? 36.50952 -8.54501  7.40538  1.000 32.37772  ? 102 ILE   A HA   1 
ATOM   1581 H HB   . ILE   A 1 105 ? 37.92384 -10.84592 6.55297  1.000 29.61877  ? 102 ILE   A HB   1 
ATOM   1582 H HG12 . ILE   A 1 105 ? 35.23787 -10.18987 5.96716  1.000 35.56403  ? 102 ILE   A HG12 1 
ATOM   1583 H HG13 . ILE   A 1 105 ? 36.42734 -9.95824  4.93910  1.000 35.56403  ? 102 ILE   A HG13 1 
ATOM   1584 H HG21 . ILE   A 1 105 ? 36.25111 -12.05791 7.76687  1.000 34.23016  ? 102 ILE   A HG21 1 
ATOM   1585 H HG22 . ILE   A 1 105 ? 37.28865 -11.28595 8.68941  1.000 34.23016  ? 102 ILE   A HG22 1 
ATOM   1586 H HG23 . ILE   A 1 105 ? 35.84095 -10.68018 8.44298  1.000 34.23016  ? 102 ILE   A HG23 1 
ATOM   1587 H HD11 . ILE   A 1 105 ? 35.38403 -12.43411 5.75147  1.000 40.65594  ? 102 ILE   A HD11 1 
ATOM   1588 H HD12 . ILE   A 1 105 ? 35.41572 -11.85648 4.27199  1.000 40.65594  ? 102 ILE   A HD12 1 
ATOM   1589 H HD13 . ILE   A 1 105 ? 36.76290 -12.32705 4.96997  1.000 40.65594  ? 102 ILE   A HD13 1 
ATOM   1590 N N    . ALA   A 1 106 ? 37.72618 -8.41979  9.52462  1.000 23.58744  ? 103 ALA   A N    1 
ATOM   1591 C CA   . ALA   A 1 106 ? 38.50570 -8.16351  10.72805 1.000 22.92332  ? 103 ALA   A CA   1 
ATOM   1592 C C    . ALA   A 1 106 ? 37.86423 -8.87508  11.90962 1.000 22.57878  ? 103 ALA   A C    1 
ATOM   1593 O O    . ALA   A 1 106 ? 36.65456 -8.75646  12.12797 1.000 25.71296  ? 103 ALA   A O    1 
ATOM   1594 C CB   . ALA   A 1 106 ? 38.61084 -6.65804  11.00281 1.000 23.60351  ? 103 ALA   A CB   1 
ATOM   1595 H H    . ALA   A 1 106 ? 36.88535 -8.26598  9.61918  1.000 28.23931  ? 103 ALA   A H    1 
ATOM   1596 H HA   . ALA   A 1 106 ? 39.40100 -8.51966  10.61624 1.000 27.44236  ? 103 ALA   A HA   1 
ATOM   1597 H HB1  . ALA   A 1 106 ? 39.20847 -6.51497  11.75332 1.000 28.25858  ? 103 ALA   A HB1  1 
ATOM   1598 H HB2  . ALA   A 1 106 ? 38.96019 -6.21650  10.21294 1.000 28.25858  ? 103 ALA   A HB2  1 
ATOM   1599 H HB3  . ALA   A 1 106 ? 37.72878 -6.31282  11.21187 1.000 28.25858  ? 103 ALA   A HB3  1 
ATOM   1600 N N    . ALA   A 1 107 ? 38.67671 -9.60864  12.66977 1.000 22.26210  ? 104 ALA   A N    1 
ATOM   1601 C CA   . ALA   A 1 107 ? 38.19745 -10.35025 13.82825 1.000 21.76428  ? 104 ALA   A CA   1 
ATOM   1602 C C    . ALA   A 1 107 ? 39.27641 -10.33996 14.90086 1.000 22.70205  ? 104 ALA   A C    1 
ATOM   1603 O O    . ALA   A 1 107 ? 40.46988 -10.38209 14.59655 1.000 24.40940  ? 104 ALA   A O    1 
ATOM   1604 C CB   . ALA   A 1 107 ? 37.82555 -11.79024 13.45907 1.000 18.40770  ? 104 ALA   A CB   1 
ATOM   1605 H H    . ALA   A 1 107 ? 39.52131 -9.69233  12.53103 1.000 26.64889  ? 104 ALA   A H    1 
ATOM   1606 H HA   . ALA   A 1 107 ? 37.40773 -9.91745  14.18870 1.000 26.05151  ? 104 ALA   A HA   1 
ATOM   1607 H HB1  . ALA   A 1 107 ? 37.52896 -12.25441 14.25750 1.000 22.02362  ? 104 ALA   A HB1  1 
ATOM   1608 H HB2  . ALA   A 1 107 ? 37.11225 -11.77361 12.80193 1.000 22.02362  ? 104 ALA   A HB2  1 
ATOM   1609 H HB3  . ALA   A 1 107 ? 38.60549 -12.23300 13.08954 1.000 22.02362  ? 104 ALA   A HB3  1 
ATOM   1610 N N    . ILE   A 1 108 ? 38.85224 -10.29293 16.16167 1.000 22.38469  ? 105 ILE   A N    1 
ATOM   1611 C CA   . ILE   A 1 108 ? 39.77148 -10.10799 17.27792 1.000 23.55757  ? 105 ILE   A CA   1 
ATOM   1612 C C    . ILE   A 1 108 ? 39.47414 -11.12305 18.37273 1.000 20.51937  ? 105 ILE   A C    1 
ATOM   1613 O O    . ILE   A 1 108 ? 38.31022 -11.41653 18.66863 1.000 20.52191  ? 105 ILE   A O    1 
ATOM   1614 C CB   . ILE   A 1 108 ? 39.69458 -8.66675  17.82973 1.000 23.37125  ? 105 ILE   A CB   1 
ATOM   1615 C CG1  . ILE   A 1 108 ? 40.68711 -8.47661  18.97891 1.000 21.51053  ? 105 ILE   A CG1  1 
ATOM   1616 C CG2  . ILE   A 1 108 ? 38.27655 -8.33777  18.28616 1.000 23.46151  ? 105 ILE   A CG2  1 
ATOM   1617 C CD1  . ILE   A 1 108 ? 40.97261 -7.02269  19.29692 1.000 22.62551  ? 105 ILE   A CD1  1 
ATOM   1618 H H    . ILE   A 1 108 ? 38.02805 -10.36669 16.39592 1.000 26.79600  ? 105 ILE   A H    1 
ATOM   1619 H HA   . ILE   A 1 108 ? 40.67461 -10.28058 16.96894 1.000 28.20345  ? 105 ILE   A HA   1 
ATOM   1620 H HB   . ILE   A 1 108 ? 39.93428 -8.05788  17.11368 1.000 27.97988  ? 105 ILE   A HB   1 
ATOM   1621 H HG12 . ILE   A 1 108 ? 40.32360 -8.88962  19.77777 1.000 25.74701  ? 105 ILE   A HG12 1 
ATOM   1622 H HG13 . ILE   A 1 108 ? 41.52702 -8.89892  18.73994 1.000 25.74701  ? 105 ILE   A HG13 1 
ATOM   1623 H HG21 . ILE   A 1 108 ? 38.23110 -7.39834  18.52342 1.000 28.08819  ? 105 ILE   A HG21 1 
ATOM   1624 H HG22 . ILE   A 1 108 ? 37.65985 -8.52614  17.56152 1.000 28.08819  ? 105 ILE   A HG22 1 
ATOM   1625 H HG23 . ILE   A 1 108 ? 38.05806 -8.88456  19.05700 1.000 28.08819  ? 105 ILE   A HG23 1 
ATOM   1626 H HD11 . ILE   A 1 108 ? 41.64404 -6.97818  19.99556 1.000 27.08498  ? 105 ILE   A HD11 1 
ATOM   1627 H HD12 . ILE   A 1 108 ? 41.29854 -6.58243  18.49639 1.000 27.08498  ? 105 ILE   A HD12 1 
ATOM   1628 H HD13 . ILE   A 1 108 ? 40.15374 -6.59850  19.59762 1.000 27.08498  ? 105 ILE   A HD13 1 
HETATM 1629 C C    . A1A7V A 1 109 ? 39.88286 -13.89376 19.78510 1.000 23.70225  ? 106 A1A7V A C    1 
HETATM 1630 N N    . A1A7V A 1 109 ? 40.54138 -11.66515 18.96420 1.000 19.16393  ? 106 A1A7V A N    1 
HETATM 1631 O O    . A1A7V A 1 109 ? 40.56236 -14.69428 19.13557 1.000 23.14717  ? 106 A1A7V A O    1 
HETATM 1632 C CA   . A1A7V A 1 109 ? 40.46080 -12.52502 20.14168 1.000 21.55996  ? 106 A1A7V A CA   1 
HETATM 1633 C CB   . A1A7V A 1 109 ? 39.65389 -11.82452 21.23910 1.000 23.80377  ? 106 A1A7V A CB   1 
HETATM 1634 S SG   . A1A7V A 1 109 ? 40.02151 -12.42354 22.90384 1.000 24.36168  ? 106 A1A7V A SG   1 
HETATM 1635 C C1   . A1A7V A 1 109 ? 38.54858 -12.65763 23.85050 0.763 23.65219  ? 106 A1A7V A C1   1 
HETATM 1636 O O1   . A1A7V A 1 109 ? 37.77321 -11.84416 23.41958 0.763 24.64679  ? 106 A1A7V A O1   1 
HETATM 1637 C C2   . A1A7V A 1 109 ? 38.08252 -14.00324 24.40115 0.763 41.82952  ? 106 A1A7V A C2   1 
HETATM 1638 O O2   . A1A7V A 1 109 ? 37.12871 -14.51903 23.50800 0.763 34.52933  ? 106 A1A7V A O2   1 
HETATM 1639 C C3   . A1A7V A 1 109 ? 39.24496 -15.00558 24.44660 0.763 45.14729  ? 106 A1A7V A C3   1 
HETATM 1640 H H    . A1A7V A 1 109 ? 41.34844 -11.54513 18.69245 1.000 22.93109  ? 106 A1A7V A H    1 
HETATM 1641 H HA   . A1A7V A 1 109 ? 41.34981 -12.68827 20.49370 1.000 25.80632  ? 106 A1A7V A HA   1 
HETATM 1642 H HB3  . A1A7V A 1 109 ? 38.70936 -11.97026 21.07323 1.000 28.49890  ? 106 A1A7V A HB3  1 
HETATM 1643 H HB2  . A1A7V A 1 109 ? 39.85240 -10.87536 21.21479 1.000 28.49890  ? 106 A1A7V A HB2  1 
HETATM 1644 H H20  . A1A7V A 1 109 ? 37.66875 -13.86266 25.42695 0.763 50.12980  ? 106 A1A7V A H20  1 
HETATM 1645 H HO2  . A1A7V A 1 109 ? 37.33340 -14.13579 22.65945 0.763 41.36956  ? 106 A1A7V A HO2  1 
HETATM 1646 H H3B  . A1A7V A 1 109 ? 38.93111 -16.01408 24.73547 0.763 54.11112  ? 106 A1A7V A H3B  1 
HETATM 1647 H H3A  . A1A7V A 1 109 ? 40.02675 -14.72420 25.15980 0.763 54.11112  ? 106 A1A7V A H3A  1 
HETATM 1648 H H3   . A1A7V A 1 109 ? 39.75186 -15.11904 23.48265 0.763 54.11112  ? 106 A1A7V A H3   1 
ATOM   1649 N N    . ALA   A 1 110 ? 38.65745 -14.19531 20.21540 1.000 20.43682  ? 107 ALA   A N    1 
ATOM   1650 C CA   . ALA   A 1 110 ? 37.98656 -15.41772 19.79115 1.000 23.44036  ? 107 ALA   A CA   1 
ATOM   1651 C C    . ALA   A 1 110 ? 37.23215 -15.24554 18.48104 1.000 23.39430  ? 107 ALA   A C    1 
ATOM   1652 O O    . ALA   A 1 110 ? 36.85314 -16.24670 17.86395 1.000 21.27747  ? 107 ALA   A O    1 
ATOM   1653 C CB   . ALA   A 1 110 ? 37.01345 -15.89863 20.87285 1.000 24.64867  ? 107 ALA   A CB   1 
ATOM   1654 H H    . ALA   A 1 110 ? 38.19675 -13.70685 20.75277 1.000 24.45856  ? 107 ALA   A H    1 
ATOM   1655 H HA   . ALA   A 1 110 ? 38.65431 -16.11068 19.66940 1.000 28.06280  ? 107 ALA   A HA   1 
ATOM   1656 H HB1  . ALA   A 1 110 ? 36.55576 -16.69278 20.55543 1.000 29.51278  ? 107 ALA   A HB1  1 
ATOM   1657 H HB2  . ALA   A 1 110 ? 37.51322 -16.10457 21.67828 1.000 29.51278  ? 107 ALA   A HB2  1 
ATOM   1658 H HB3  . ALA   A 1 110 ? 36.36974 -15.19587 21.05360 1.000 29.51278  ? 107 ALA   A HB3  1 
ATOM   1659 N N    . GLY   A 1 111 ? 37.01047 -13.99902 18.04243 1.000 20.48907  ? 108 GLY   A N    1 
ATOM   1660 C CA   . GLY   A 1 111 ? 36.29525 -13.75438 16.80980 1.000 21.83115  ? 108 GLY   A CA   1 
ATOM   1661 C C    . GLY   A 1 111 ? 36.79392 -14.52381 15.60833 1.000 22.19984  ? 108 GLY   A C    1 
ATOM   1662 O O    . GLY   A 1 111 ? 35.97862 -15.01642 14.81771 1.000 24.87045  ? 108 GLY   A O    1 
ATOM   1663 H H    . GLY   A 1 111 ? 37.26844 -13.28606 18.44831 1.000 24.52126  ? 108 GLY   A H    1 
ATOM   1664 H HA2  . GLY   A 1 111 ? 35.36324 -13.98834 16.94214 1.000 26.13175  ? 108 GLY   A HA2  1 
ATOM   1665 H HA3  . GLY   A 1 111 ? 36.35687 -12.80944 16.59957 1.000 26.13175  ? 108 GLY   A HA3  1 
ATOM   1666 N N    . PRO   A 1 112 ? 38.11051 -14.65214 15.42068 1.000 18.34097  ? 109 PRO   A N    1 
ATOM   1667 C CA   . PRO   A 1 112 ? 38.61058 -15.37781 14.24190 1.000 22.79723  ? 109 PRO   A CA   1 
ATOM   1668 C C    . PRO   A 1 112 ? 38.10562 -16.80460 14.13320 1.000 23.29950  ? 109 PRO   A C    1 
ATOM   1669 O O    . PRO   A 1 112 ? 38.07158 -17.34501 13.01993 1.000 25.30250  ? 109 PRO   A O    1 
ATOM   1670 C CB   . PRO   A 1 112 ? 40.13404 -15.33713 14.42629 1.000 21.77800  ? 109 PRO   A CB   1 
ATOM   1671 C CG   . PRO   A 1 112 ? 40.37723 -14.12145 15.25107 1.000 20.84508  ? 109 PRO   A CG   1 
ATOM   1672 C CD   . PRO   A 1 112 ? 39.20759 -14.04222 16.19315 1.000 22.43443  ? 109 PRO   A CD   1 
ATOM   1673 H HA   . PRO   A 1 112 ? 38.36897 -14.89652 13.43513 1.000 27.29105  ? 109 PRO   A HA   1 
ATOM   1674 H HB2  . PRO   A 1 112 ? 40.43448 -16.13664 14.88610 1.000 26.06797  ? 109 PRO   A HB2  1 
ATOM   1675 H HB3  . PRO   A 1 112 ? 40.57135 -15.26660 13.56334 1.000 26.06797  ? 109 PRO   A HB3  1 
ATOM   1676 H HG2  . PRO   A 1 112 ? 41.20946 -14.21609 15.74030 1.000 24.94847  ? 109 PRO   A HG2  1 
ATOM   1677 H HG3  . PRO   A 1 112 ? 40.41517 -13.33806 14.68031 1.000 24.94847  ? 109 PRO   A HG3  1 
ATOM   1678 H HD2  . PRO   A 1 112 ? 39.38169 -14.54652 17.00326 1.000 26.85569  ? 109 PRO   A HD2  1 
ATOM   1679 H HD3  . PRO   A 1 112 ? 39.00360 -13.11996 16.41387 1.000 26.85569  ? 109 PRO   A HD3  1 
ATOM   1680 N N    . THR   A 1 113 ? 37.71152 -17.43816 15.24059 1.000 22.78919  ? 110 THR   A N    1 
ATOM   1681 C CA   . THR   A 1 113 ? 37.21643 -18.80698 15.15300 1.000 21.47167  ? 110 THR   A CA   1 
ATOM   1682 C C    . THR   A 1 113 ? 35.93889 -18.89450 14.32873 1.000 25.61140  ? 110 THR   A C    1 
ATOM   1683 O O    . THR   A 1 113 ? 35.60874 -19.97622 13.83113 1.000 26.03552  ? 110 THR   A O    1 
ATOM   1684 C CB   . THR   A 1 113 ? 36.97653 -19.38869 16.54991 1.000 26.32149  ? 110 THR   A CB   1 
ATOM   1685 O OG1  . THR   A 1 113 ? 35.91872 -18.67645 17.20332 1.000 25.80953  ? 110 THR   A OG1  1 
ATOM   1686 C CG2  . THR   A 1 113 ? 38.24681 -19.30634 17.39043 1.000 26.31036  ? 110 THR   A CG2  1 
ATOM   1687 H H    . THR   A 1 113 ? 37.72153 -17.10414 16.03301 1.000 27.28140  ? 110 THR   A H    1 
ATOM   1688 H HA   . THR   A 1 113 ? 37.89549 -19.35201 14.72553 1.000 25.70038  ? 110 THR   A HA   1 
ATOM   1689 H HB   . THR   A 1 113 ? 36.72503 -20.32202 16.46908 1.000 31.52016  ? 110 THR   A HB   1 
ATOM   1690 H HG1  . THR   A 1 113 ? 36.12573 -17.86653 17.28563 1.000 30.90581  ? 110 THR   A HG1  1 
ATOM   1691 H HG21 . THR   A 1 113 ? 38.45971 -18.37916 17.57992 1.000 31.50680  ? 110 THR   A HG21 1 
ATOM   1692 H HG22 . THR   A 1 113 ? 38.12117 -19.77813 18.22861 1.000 31.50680  ? 110 THR   A HG22 1 
ATOM   1693 H HG23 . THR   A 1 113 ? 38.98835 -19.70801 16.91119 1.000 31.50680  ? 110 THR   A HG23 1 
ATOM   1694 N N    . ALA   A 1 114 ? 35.21534 -17.78219 14.17067 1.000 23.43170  ? 111 ALA   A N    1 
ATOM   1695 C CA   . ALA   A 1 114 ? 34.06123 -17.77664 13.27862 1.000 27.13900  ? 111 ALA   A CA   1 
ATOM   1696 C C    . ALA   A 1 114 ? 34.48128 -17.94643 11.82474 1.000 27.18342  ? 111 ALA   A C    1 
ATOM   1697 O O    . ALA   A 1 114 ? 33.71419 -18.48353 11.01775 1.000 31.03523  ? 111 ALA   A O    1 
ATOM   1698 C CB   . ALA   A 1 114 ? 33.26720 -16.48189 13.44880 1.000 28.37230  ? 111 ALA   A CB   1 
ATOM   1699 H H    . ALA   A 1 114 ? 35.37084 -17.03253 14.56237 1.000 28.05241  ? 111 ALA   A H    1 
ATOM   1700 H HA   . ALA   A 1 114 ? 33.48083 -18.51649 13.51666 1.000 32.50118  ? 111 ALA   A HA   1 
ATOM   1701 H HB1  . ALA   A 1 114 ? 32.50349 -16.49889 12.85101 1.000 33.98113  ? 111 ALA   A HB1  1 
ATOM   1702 H HB2  . ALA   A 1 114 ? 32.96600 -16.41470 14.36841 1.000 33.98113  ? 111 ALA   A HB2  1 
ATOM   1703 H HB3  . ALA   A 1 114 ? 33.83989 -15.72947 13.23249 1.000 33.98113  ? 111 ALA   A HB3  1 
ATOM   1704 N N    . LEU   A 1 115 ? 35.68676 -17.49344 11.47148 1.000 21.54673  ? 112 LEU   A N    1 
ATOM   1705 C CA   . LEU   A 1 115 ? 36.17250 -17.67855 10.10838 1.000 22.89278  ? 112 LEU   A CA   1 
ATOM   1706 C C    . LEU   A 1 115 ? 36.36325 -19.15537 9.79206  1.000 26.16014  ? 112 LEU   A C    1 
ATOM   1707 O O    . LEU   A 1 115 ? 36.06851 -19.60291 8.67762  1.000 24.08732  ? 112 LEU   A O    1 
ATOM   1708 C CB   . LEU   A 1 115 ? 37.48280 -16.91829 9.90993  1.000 27.13225  ? 112 LEU   A CB   1 
ATOM   1709 C CG   . LEU   A 1 115 ? 37.46803 -15.44271 10.31332 1.000 29.15751  ? 112 LEU   A CG   1 
ATOM   1710 C CD1  . LEU   A 1 115 ? 38.83440 -14.82407 10.07351 1.000 33.36719  ? 112 LEU   A CD1  1 
ATOM   1711 C CD2  . LEU   A 1 115 ? 36.38968 -14.68089 9.56092  1.000 34.79486  ? 112 LEU   A CD2  1 
ATOM   1712 H H    . LEU   A 1 115 ? 36.23213 -17.08285 11.99453 1.000 25.79045  ? 112 LEU   A H    1 
ATOM   1713 H HA   . LEU   A 1 115 ? 35.51791 -17.31659 9.49081  1.000 27.40571  ? 112 LEU   A HA   1 
ATOM   1714 H HB2  . LEU   A 1 115 ? 38.16877 -17.35418 10.43941 1.000 32.49307  ? 112 LEU   A HB2  1 
ATOM   1715 H HB3  . LEU   A 1 115 ? 37.71548 -16.95676 8.96904  1.000 32.49307  ? 112 LEU   A HB3  1 
ATOM   1716 H HG   . LEU   A 1 115 ? 37.26263 -15.37505 11.25891 1.000 34.92339  ? 112 LEU   A HG   1 
ATOM   1717 H HD11 . LEU   A 1 115 ? 38.81176 -13.89326 10.34552 1.000 39.97500  ? 112 LEU   A HD11 1 
ATOM   1718 H HD12 . LEU   A 1 115 ? 39.49504 -15.30535 10.59583 1.000 39.97500  ? 112 LEU   A HD12 1 
ATOM   1719 H HD13 . LEU   A 1 115 ? 39.04862 -14.88773 9.12961  1.000 39.97500  ? 112 LEU   A HD13 1 
ATOM   1720 H HD21 . LEU   A 1 115 ? 36.47518 -13.73503 9.75824  1.000 41.68821  ? 112 LEU   A HD21 1 
ATOM   1721 H HD22 . LEU   A 1 115 ? 36.50202 -14.83175 8.60933  1.000 41.68821  ? 112 LEU   A HD22 1 
ATOM   1722 H HD23 . LEU   A 1 115 ? 35.51955 -15.00095 9.84611  1.000 41.68821  ? 112 LEU   A HD23 1 
ATOM   1723 N N    . LEU   A 1 116 ? 36.86226 -19.92832 10.75922 1.000 24.16616  ? 113 LEU   A N    1 
ATOM   1724 C CA   . LEU   A 1 116 ? 37.00526 -21.36565 10.55598 1.000 28.57019  ? 113 LEU   A CA   1 
ATOM   1725 C C    . LEU   A 1 116 ? 35.64305 -22.02796 10.39781 1.000 27.07018  ? 113 LEU   A C    1 
ATOM   1726 O O    . LEU   A 1 116 ? 35.44496 -22.86089 9.50618  1.000 25.99568  ? 113 LEU   A O    1 
ATOM   1727 C CB   . LEU   A 1 116 ? 37.77270 -21.98519 11.72448 1.000 23.90683  ? 113 LEU   A CB   1 
ATOM   1728 C CG   . LEU   A 1 116 ? 37.85138 -23.51456 11.73897 1.000 33.98744  ? 113 LEU   A CG   1 
ATOM   1729 C CD1  . LEU   A 1 116 ? 38.60650 -24.03018 10.52387 1.000 26.73213  ? 113 LEU   A CD1  1 
ATOM   1730 C CD2  . LEU   A 1 116 ? 38.49914 -24.00229 13.02381 1.000 31.21816  ? 113 LEU   A CD2  1 
ATOM   1731 H H    . LEU   A 1 116 ? 37.12096 -19.64762 11.52986 1.000 28.93376  ? 113 LEU   A H    1 
ATOM   1732 H HA   . LEU   A 1 116 ? 37.51530 -21.52091 9.74564  1.000 34.21860  ? 113 LEU   A HA   1 
ATOM   1733 H HB2  . LEU   A 1 116 ? 38.68291 -21.65080 11.69992 1.000 28.62257  ? 113 LEU   A HB2  1 
ATOM   1734 H HB3  . LEU   A 1 116 ? 37.34096 -21.71179 12.54895 1.000 28.62257  ? 113 LEU   A HB3  1 
ATOM   1735 H HG   . LEU   A 1 116 ? 36.95157 -23.87482 11.70068 1.000 40.71930  ? 113 LEU   A HG   1 
ATOM   1736 H HD11 . LEU   A 1 116 ? 38.66453 -24.99709 10.57500 1.000 32.01293  ? 113 LEU   A HD11 1 
ATOM   1737 H HD12 . LEU   A 1 116 ? 38.12859 -23.76948 9.72103  1.000 32.01293  ? 113 LEU   A HD12 1 
ATOM   1738 H HD13 . LEU   A 1 116 ? 39.49681 -23.64519 10.51855 1.000 32.01293  ? 113 LEU   A HD13 1 
ATOM   1739 H HD21 . LEU   A 1 116 ? 38.56734 -24.96948 12.99571 1.000 37.39617  ? 113 LEU   A HD21 1 
ATOM   1740 H HD22 . LEU   A 1 116 ? 39.38317 -23.61044 13.10029 1.000 37.39617  ? 113 LEU   A HD22 1 
ATOM   1741 H HD23 . LEU   A 1 116 ? 37.95085 -23.73108 13.77662 1.000 37.39617  ? 113 LEU   A HD23 1 
ATOM   1742 N N    . ALA   A 1 117 ? 34.68953 -21.66684 11.25927 1.000 26.54494  ? 114 ALA   A N    1 
ATOM   1743 C CA   . ALA   A 1 117 ? 33.36042 -22.26303 11.18717 1.000 27.82517  ? 114 ALA   A CA   1 
ATOM   1744 C C    . ALA   A 1 117 ? 32.73201 -22.05258 9.81622  1.000 31.63762  ? 114 ALA   A C    1 
ATOM   1745 O O    . ALA   A 1 117 ? 32.02834 -22.93189 9.30566  1.000 33.27981  ? 114 ALA   A O    1 
ATOM   1746 C CB   . ALA   A 1 117 ? 32.46530 -21.67456 12.27752 1.000 29.75533  ? 114 ALA   A CB   1 
ATOM   1747 H H    . ALA   A 1 117 ? 34.78701 -21.08619 11.88612 1.000 31.78830  ? 114 ALA   A H    1 
ATOM   1748 H HA   . ALA   A 1 117 ? 33.43901 -23.21786 11.33890 1.000 33.32457  ? 114 ALA   A HA   1 
ATOM   1749 H HB1  . ALA   A 1 117 ? 31.58496 -22.07698 12.21471 1.000 35.64077  ? 114 ALA   A HB1  1 
ATOM   1750 H HB2  . ALA   A 1 117 ? 32.85573 -21.86668 13.14444 1.000 35.64077  ? 114 ALA   A HB2  1 
ATOM   1751 H HB3  . ALA   A 1 117 ? 32.40041 -20.71527 12.14923 1.000 35.64077  ? 114 ALA   A HB3  1 
ATOM   1752 N N    . HIS   A 1 118 ? 32.97321 -20.89470 9.20557  1.000 30.52229  ? 115 HIS   A N    1 
ATOM   1753 C CA   . HIS   A 1 118 ? 32.36618 -20.53826 7.93186  1.000 32.55457  ? 115 HIS   A CA   1 
ATOM   1754 C C    . HIS   A 1 118 ? 33.31522 -20.73008 6.75467  1.000 31.12017  ? 115 HIS   A C    1 
ATOM   1755 O O    . HIS   A 1 118 ? 32.98480 -20.32867 5.63433  1.000 32.11359  ? 115 HIS   A O    1 
ATOM   1756 C CB   . HIS   A 1 118 ? 31.86551 -19.09254 7.98582  1.000 31.81683  ? 115 HIS   A CB   1 
ATOM   1757 C CG   . HIS   A 1 118 ? 30.84094 -18.85214 9.05234  1.000 33.03070  ? 115 HIS   A CG   1 
ATOM   1758 N ND1  . HIS   A 1 118 ? 29.73822 -19.66182 9.21859  1.000 33.57430  ? 115 HIS   A ND1  1 
ATOM   1759 C CD2  . HIS   A 1 118 ? 30.75300 -17.89789 10.00940 1.000 39.53708  ? 115 HIS   A CD2  1 
ATOM   1760 C CE1  . HIS   A 1 118 ? 29.01439 -19.21710 10.23005 1.000 30.22991  ? 115 HIS   A CE1  1 
ATOM   1761 N NE2  . HIS   A 1 118 ? 29.60769 -18.14697 10.72691 1.000 29.11047  ? 115 HIS   A NE2  1 
ATOM   1762 H H    . HIS   A 1 118 ? 33.49655 -20.28820 9.51841  1.000 36.56112  ? 115 HIS   A H    1 
ATOM   1763 H HA   . HIS   A 1 118 ? 31.59981 -21.11267 7.77817  1.000 38.99986  ? 115 HIS   A HA   1 
ATOM   1764 H HB2  . HIS   A 1 118 ? 32.61895 -18.50721 8.16080  1.000 38.11457  ? 115 HIS   A HB2  1 
ATOM   1765 H HB3  . HIS   A 1 118 ? 31.46310 -18.86910 7.13198  1.000 38.11457  ? 115 HIS   A HB3  1 
ATOM   1766 H HD2  . HIS   A 1 118 ? 31.35501 -17.20394 10.15397 1.000 47.37887  ? 115 HIS   A HD2  1 
ATOM   1767 H HE1  . HIS   A 1 118 ? 28.22218 -19.59335 10.53948 1.000 36.21027  ? 115 HIS   A HE1  1 
ATOM   1768 H HE2  . HIS   A 1 118 ? 29.32340 -17.68140 11.39176 1.000 34.86694  ? 115 HIS   A HE2  1 
ATOM   1769 N N    . GLU   A 1 119 ? 34.48325 -21.33423 6.98355  1.000 28.28817  ? 116 GLU   A N    1 
ATOM   1770 C CA   . GLU   A 1 119 ? 35.41656 -21.68771 5.91263  1.000 31.54791  ? 116 GLU   A CA   1 
ATOM   1771 C C    . GLU   A 1 119 ? 35.86537 -20.44820 5.14030  1.000 29.88900  ? 116 GLU   A C    1 
ATOM   1772 O O    . GLU   A 1 119 ? 35.84930 -20.41263 3.90786  1.000 30.30804  ? 116 GLU   A O    1 
ATOM   1773 C CB   . GLU   A 1 119 ? 34.79507 -22.72732 4.97417  1.000 33.44070  ? 116 GLU   A CB   1 
ATOM   1774 C CG   . GLU   A 1 119 ? 34.39673 -24.01906 5.67502  1.000 46.39127  ? 116 GLU   A CG   1 
ATOM   1775 C CD   . GLU   A 1 119 ? 33.94972 -25.10343 4.71139  1.000 52.86490  ? 116 GLU   A CD   1 
ATOM   1776 O OE1  . GLU   A 1 119 ? 33.77106 -24.80523 3.51107  1.000 57.30395  ? 116 GLU   A OE1  1 
ATOM   1777 O OE2  . GLU   A 1 119 ? 33.77993 -26.25769 5.15689  1.000 55.52089  ? 116 GLU   A OE2  1 
ATOM   1778 H H    . GLU   A 1 119 ? 34.76285 -21.55393 7.76659  1.000 33.88017  ? 116 GLU   A H    1 
ATOM   1779 H HA   . GLU   A 1 119 ? 36.20934 -22.07853 6.31221  1.000 37.79186  ? 116 GLU   A HA   1 
ATOM   1780 H HB2  . GLU   A 1 119 ? 33.99710 -22.34883 4.57306  1.000 40.06321  ? 116 GLU   A HB2  1 
ATOM   1781 H HB3  . GLU   A 1 119 ? 35.43939 -22.95032 4.28423  1.000 40.06321  ? 116 GLU   A HB3  1 
ATOM   1782 H HG2  . GLU   A 1 119 ? 35.15877 -24.35610 6.17159  1.000 55.60390  ? 116 GLU   A HG2  1 
ATOM   1783 H HG3  . GLU   A 1 119 ? 33.66130 -23.83536 6.28024  1.000 55.60390  ? 116 GLU   A HG3  1 
ATOM   1784 N N    . ILE   A 1 120 ? 36.28676 -19.42684 5.88261  1.000 29.67556  ? 117 ILE   A N    1 
ATOM   1785 C CA   . ILE   A 1 120 ? 36.68703 -18.14322 5.31877  1.000 26.34490  ? 117 ILE   A CA   1 
ATOM   1786 C C    . ILE   A 1 120 ? 38.20350 -18.02427 5.38884  1.000 28.21847  ? 117 ILE   A C    1 
ATOM   1787 O O    . ILE   A 1 120 ? 38.80486 -18.26342 6.44317  1.000 28.25383  ? 117 ILE   A O    1 
ATOM   1788 C CB   . ILE   A 1 120 ? 36.01850 -16.97085 6.05905  1.000 24.77508  ? 117 ILE   A CB   1 
ATOM   1789 C CG1  . ILE   A 1 120 ? 34.49172 -17.08997 6.00378  1.000 30.68137  ? 117 ILE   A CG1  1 
ATOM   1790 C CG2  . ILE   A 1 120 ? 36.47775 -15.64359 5.46966  1.000 26.54522  ? 117 ILE   A CG2  1 
ATOM   1791 C CD1  . ILE   A 1 120 ? 33.90225 -16.94513 4.60937  1.000 30.99925  ? 117 ILE   A CD1  1 
ATOM   1792 H H    . ILE   A 1 120 ? 36.35050 -19.45630 6.73973  1.000 35.54505  ? 117 ILE   A H    1 
ATOM   1793 H HA   . ILE   A 1 120 ? 36.42291 -18.11628 4.38580  1.000 31.54825  ? 117 ILE   A HA   1 
ATOM   1794 H HB   . ILE   A 1 120 ? 36.28776 -17.00687 6.99023  1.000 29.66447  ? 117 ILE   A HB   1 
ATOM   1795 H HG12 . ILE   A 1 120 ? 34.23679 -17.96296 6.34114  1.000 36.75201  ? 117 ILE   A HG12 1 
ATOM   1796 H HG13 . ILE   A 1 120 ? 34.10650 -16.39423 6.55916  1.000 36.75201  ? 117 ILE   A HG13 1 
ATOM   1797 H HG21 . ILE   A 1 120 ? 35.86543 -14.94517 5.74923  1.000 31.78864  ? 117 ILE   A HG21 1 
ATOM   1798 H HG22 . ILE   A 1 120 ? 37.37178 -15.44782 5.79105  1.000 31.78864  ? 117 ILE   A HG22 1 
ATOM   1799 H HG23 . ILE   A 1 120 ? 36.48171 -15.71222 4.50210  1.000 31.78864  ? 117 ILE   A HG23 1 
ATOM   1800 H HD11 . ILE   A 1 120 ? 32.93609 -17.00956 4.66668  1.000 37.13347  ? 117 ILE   A HD11 1 
ATOM   1801 H HD12 . ILE   A 1 120 ? 34.15528 -16.08138 4.24769  1.000 37.13347  ? 117 ILE   A HD12 1 
ATOM   1802 H HD13 . ILE   A 1 120 ? 34.24815 -17.65422 4.04506  1.000 37.13347  ? 117 ILE   A HD13 1 
ATOM   1803 N N    . GLY   A 1 121 ? 38.81700 -17.66183 4.26486  1.000 26.71722  ? 118 GLY   A N    1 
ATOM   1804 C CA   . GLY   A 1 121 ? 40.21922 -17.28813 4.25076  1.000 27.54278  ? 118 GLY   A CA   1 
ATOM   1805 C C    . GLY   A 1 121 ? 41.20340 -18.39362 4.56384  1.000 27.41335  ? 118 GLY   A C    1 
ATOM   1806 O O    . GLY   A 1 121 ? 42.29624 -18.10981 5.06490  1.000 22.43996  ? 118 GLY   A O    1 
ATOM   1807 H H    . GLY   A 1 121 ? 38.43767 -17.62504 3.49392  1.000 31.99504  ? 118 GLY   A H    1 
ATOM   1808 H HA2  . GLY   A 1 121 ? 40.43633 -16.94677 3.36915  1.000 32.98571  ? 118 GLY   A HA2  1 
ATOM   1809 H HA3  . GLY   A 1 121 ? 40.35517 -16.58429 4.90423  1.000 32.98571  ? 118 GLY   A HA3  1 
ATOM   1810 N N    . PHE   A 1 122 ? 40.85693 -19.64804 4.27864  1.000 25.59135  ? 119 PHE   A N    1 
ATOM   1811 C CA   . PHE   A 1 122 ? 41.80575 -20.73768 4.47076  1.000 28.11967  ? 119 PHE   A CA   1 
ATOM   1812 C C    . PHE   A 1 122 ? 43.11476 -20.43313 3.75137  1.000 29.78940  ? 119 PHE   A C    1 
ATOM   1813 O O    . PHE   A 1 122 ? 43.12355 -19.87970 2.64846  1.000 23.87140  ? 119 PHE   A O    1 
ATOM   1814 C CB   . PHE   A 1 122 ? 41.22759 -22.05734 3.95508  1.000 27.81973  ? 119 PHE   A CB   1 
ATOM   1815 C CG   . PHE   A 1 122 ? 40.21878 -22.69251 4.87488  1.000 29.14515  ? 119 PHE   A CG   1 
ATOM   1816 C CD1  . PHE   A 1 122 ? 39.76933 -22.04060 6.01204  1.000 25.07725  ? 119 PHE   A CD1  1 
ATOM   1817 C CD2  . PHE   A 1 122 ? 39.72952 -23.95840 4.60037  1.000 30.08209  ? 119 PHE   A CD2  1 
ATOM   1818 C CE1  . PHE   A 1 122 ? 38.84665 -22.63698 6.84965  1.000 30.24856  ? 119 PHE   A CE1  1 
ATOM   1819 C CE2  . PHE   A 1 122 ? 38.80828 -24.55824 5.43419  1.000 33.58215  ? 119 PHE   A CE2  1 
ATOM   1820 C CZ   . PHE   A 1 122 ? 38.36572 -23.89722 6.56067  1.000 26.93765  ? 119 PHE   A CZ   1 
ATOM   1821 H H    . PHE   A 1 122 ? 40.08875 -19.88968 3.97682  1.000 30.64399  ? 119 PHE   A H    1 
ATOM   1822 H HA   . PHE   A 1 122 ? 41.98245 -20.83822 5.41922  1.000 33.67798  ? 119 PHE   A HA   1 
ATOM   1823 H HB2  . PHE   A 1 122 ? 40.78831 -21.89247 3.10611  1.000 33.31804  ? 119 PHE   A HB2  1 
ATOM   1824 H HB3  . PHE   A 1 122 ? 41.95447 -22.68840 3.83547  1.000 33.31804  ? 119 PHE   A HB3  1 
ATOM   1825 H HD1  . PHE   A 1 122 ? 40.09240 -21.19214 6.21364  1.000 30.02707  ? 119 PHE   A HD1  1 
ATOM   1826 H HD2  . PHE   A 1 122 ? 40.02590 -24.41052 3.84363  1.000 36.03288  ? 119 PHE   A HD2  1 
ATOM   1827 H HE1  . PHE   A 1 122 ? 38.54970 -22.18876 7.60847  1.000 36.23264  ? 119 PHE   A HE1  1 
ATOM   1828 H HE2  . PHE   A 1 122 ? 38.48595 -25.40792 5.23664  1.000 40.23295  ? 119 PHE   A HE2  1 
ATOM   1829 H HZ   . PHE   A 1 122 ? 37.74482 -24.29989 7.12391  1.000 32.25955  ? 119 PHE   A HZ   1 
ATOM   1830 N N    . GLY   A 1 123 ? 44.22599 -20.80613 4.38481  1.000 26.04573  ? 120 GLY   A N    1 
ATOM   1831 C CA   . GLY   A 1 123 ? 45.54180 -20.53083 3.85674  1.000 21.85554  ? 120 GLY   A CA   1 
ATOM   1832 C C    . GLY   A 1 123 ? 46.15821 -19.23619 4.33573  1.000 22.69584  ? 120 GLY   A C    1 
ATOM   1833 O O    . GLY   A 1 123 ? 47.32993 -18.97734 4.03312  1.000 25.62823  ? 120 GLY   A O    1 
ATOM   1834 H H    . GLY   A 1 123 ? 44.23468 -21.22697 5.13475  1.000 31.18924  ? 120 GLY   A H    1 
ATOM   1835 H HA2  . GLY   A 1 123 ? 46.13639 -21.25387 4.11087  1.000 26.16102  ? 120 GLY   A HA2  1 
ATOM   1836 H HA3  . GLY   A 1 123 ? 45.48676 -20.49253 2.88907  1.000 26.16102  ? 120 GLY   A HA3  1 
ATOM   1837 N N    . SER   A 1 124 ? 45.41452 -18.41907 5.07178  1.000 26.98879  ? 121 SER   A N    1 
ATOM   1838 C CA   . SER   A 1 124 ? 45.90598 -17.13497 5.54069  1.000 25.61658  ? 121 SER   A CA   1 
ATOM   1839 C C    . SER   A 1 124 ? 46.65448 -17.29049 6.85895  1.000 24.57949  ? 121 SER   A C    1 
ATOM   1840 O O    . SER   A 1 124 ? 46.43780 -18.23542 7.62194  1.000 23.74350  ? 121 SER   A O    1 
ATOM   1841 C CB   . SER   A 1 124 ? 44.75025 -16.14922 5.72504  1.000 31.99554  ? 121 SER   A CB   1 
ATOM   1842 O OG   . SER   A 1 124 ? 44.01400 -15.98501 4.52676  1.000 35.85424  ? 121 SER   A OG   1 
ATOM   1843 H H    . SER   A 1 124 ? 44.60799 -18.59079 5.31597  1.000 32.32093  ? 121 SER   A H    1 
ATOM   1844 H HA   . SER   A 1 124 ? 46.51784 -16.77380 4.88032  1.000 30.67427  ? 121 SER   A HA   1 
ATOM   1845 H HB2  . SER   A 1 124 ? 44.15672 -16.48745 6.41368  1.000 38.32902  ? 121 SER   A HB2  1 
ATOM   1846 H HB3  . SER   A 1 124 ? 45.11134 -15.28922 5.99134  1.000 38.32902  ? 121 SER   A HB3  1 
ATOM   1847 H HG   . SER   A 1 124 ? 43.67711 -16.71838 4.29377  1.000 42.95947  ? 121 SER   A HG   1 
ATOM   1848 N N    . LYS   A 1 125 ? 47.54917 -16.34113 7.11623  1.000 24.99434  ? 122 LYS   A N    1 
ATOM   1849 C CA   . LYS   A 1 125 ? 48.18130 -16.22654 8.42200  1.000 22.53282  ? 122 LYS   A CA   1 
ATOM   1850 C C    . LYS   A 1 125 ? 47.26097 -15.43828 9.34666  1.000 24.25644  ? 122 LYS   A C    1 
ATOM   1851 O O    . LYS   A 1 125 ? 46.80267 -14.34707 8.99462  1.000 24.43525  ? 122 LYS   A O    1 
ATOM   1852 C CB   . LYS   A 1 125 ? 49.54140 -15.54182 8.30054  1.000 26.62405  ? 122 LYS   A CB   1 
ATOM   1853 C CG   . LYS   A 1 125 ? 50.34831 -15.52095 9.59159  1.000 40.67416  ? 122 LYS   A CG   1 
ATOM   1854 C CD   . LYS   A 1 125 ? 51.71441 -14.87409 9.39539  1.000 44.00816  ? 122 LYS   A CD   1 
ATOM   1855 C CE   . LYS   A 1 125 ? 52.63346 -15.73389 8.53900  1.000 61.81697  ? 122 LYS   A CE   1 
ATOM   1856 N NZ   . LYS   A 1 125 ? 53.99672 -15.14560 8.42435  1.000 79.52638  ? 122 LYS   A NZ   1 
ATOM   1857 H H    . LYS   A 1 125 ? 47.80710 -15.74950 6.54785  1.000 29.92757  ? 122 LYS   A H    1 
ATOM   1858 H HA   . LYS   A 1 125 ? 48.33164 -17.10650 8.80143  1.000 26.97376  ? 122 LYS   A HA   1 
ATOM   1859 H HB2  . LYS   A 1 125 ? 50.06618 -16.01118 7.63331  1.000 31.88323  ? 122 LYS   A HB2  1 
ATOM   1860 H HB3  . LYS   A 1 125 ? 49.40188 -14.62198 8.02605  1.000 31.88323  ? 122 LYS   A HB3  1 
ATOM   1861 H HG2  . LYS   A 1 125 ? 49.86565 -15.01326 10.26256 1.000 48.74336  ? 122 LYS   A HG2  1 
ATOM   1862 H HG3  . LYS   A 1 125 ? 50.48465 -16.43093 9.89859  1.000 48.74336  ? 122 LYS   A HG3  1 
ATOM   1863 H HD2  . LYS   A 1 125 ? 51.60209 -14.01784 8.95368  1.000 52.74416  ? 122 LYS   A HD2  1 
ATOM   1864 H HD3  . LYS   A 1 125 ? 52.13573 -14.74861 10.26005 1.000 52.74416  ? 122 LYS   A HD3  1 
ATOM   1865 H HE2  . LYS   A 1 125 ? 52.71517 -16.61287 8.94102  1.000 74.11474  ? 122 LYS   A HE2  1 
ATOM   1866 H HE3  . LYS   A 1 125 ? 52.26007 -15.81045 7.64702  1.000 74.11474  ? 122 LYS   A HE3  1 
ATOM   1867 H HZ1  . LYS   A 1 125 ? 54.37868 -15.10372 9.22713  1.000 95.36603  ? 122 LYS   A HZ1  1 
ATOM   1868 H HZ2  . LYS   A 1 125 ? 54.50115 -15.64806 7.89033  1.000 95.36603  ? 122 LYS   A HZ2  1 
ATOM   1869 H HZ3  . LYS   A 1 125 ? 53.94629 -14.32426 8.08529  1.000 95.36603  ? 122 LYS   A HZ3  1 
ATOM   1870 N N    . VAL   A 1 126 ? 46.97886 -15.99757 10.52503 1.000 24.75081  ? 123 VAL   A N    1 
ATOM   1871 C CA   . VAL   A 1 126 ? 46.03288 -15.40634 11.46181 1.000 22.42249  ? 123 VAL   A CA   1 
ATOM   1872 C C    . VAL   A 1 126 ? 46.59617 -15.48726 12.87273 1.000 23.66131  ? 123 VAL   A C    1 
ATOM   1873 O O    . VAL   A 1 126 ? 47.48137 -16.29130 13.17248 1.000 22.57932  ? 123 VAL   A O    1 
ATOM   1874 C CB   . VAL   A 1 126 ? 44.65125 -16.10208 11.41943 1.000 25.27835  ? 123 VAL   A CB   1 
ATOM   1875 C CG1  . VAL   A 1 126 ? 44.05541 -16.03877 10.02455 1.000 25.34294  ? 123 VAL   A CG1  1 
ATOM   1876 C CG2  . VAL   A 1 126 ? 44.77094 -17.54562 11.89270 1.000 24.51158  ? 123 VAL   A CG2  1 
ATOM   1877 H H    . VAL   A 1 126 ? 47.33026 -16.73091 10.80489 1.000 29.63534  ? 123 VAL   A H    1 
ATOM   1878 H HA   . VAL   A 1 126 ? 45.92122 -14.47051 11.23235 1.000 26.84137  ? 123 VAL   A HA   1 
ATOM   1879 H HB   . VAL   A 1 126 ? 44.04792 -15.63493 12.01832 1.000 30.26840  ? 123 VAL   A HB   1 
ATOM   1880 H HG11 . VAL   A 1 126 ? 43.16291 -16.41816 10.04487 1.000 30.34590  ? 123 VAL   A HG11 1 
ATOM   1881 H HG12 . VAL   A 1 126 ? 44.01460 -15.11225 9.74033  1.000 30.34590  ? 123 VAL   A HG12 1 
ATOM   1882 H HG13 . VAL   A 1 126 ? 44.61689 -16.54641 9.41797  1.000 30.34590  ? 123 VAL   A HG13 1 
ATOM   1883 H HG21 . VAL   A 1 126 ? 43.97007 -18.02932 11.63671 1.000 29.34826  ? 123 VAL   A HG21 1 
ATOM   1884 H HG22 . VAL   A 1 126 ? 45.54870 -17.95050 11.47789 1.000 29.34826  ? 123 VAL   A HG22 1 
ATOM   1885 H HG23 . VAL   A 1 126 ? 44.86847 -17.55451 12.85775 1.000 29.34826  ? 123 VAL   A HG23 1 
ATOM   1886 N N    . THR   A 1 127 ? 46.05949 -14.63816 13.74456 1.000 23.36655  ? 124 THR   A N    1 
ATOM   1887 C CA   . THR   A 1 127 ? 46.31880 -14.71625 15.17168 1.000 19.78009  ? 124 THR   A CA   1 
ATOM   1888 C C    . THR   A 1 127 ? 44.99020 -14.72650 15.91332 1.000 22.61762  ? 124 THR   A C    1 
ATOM   1889 O O    . THR   A 1 127 ? 43.95245 -14.31860 15.38505 1.000 24.02967  ? 124 THR   A O    1 
ATOM   1890 C CB   . THR   A 1 127 ? 47.18451 -13.55156 15.67204 1.000 24.42095  ? 124 THR   A CB   1 
ATOM   1891 O OG1  . THR   A 1 127 ? 47.65181 -13.83981 16.99729 1.000 22.02079  ? 124 THR   A OG1  1 
ATOM   1892 C CG2  . THR   A 1 127 ? 46.38681 -12.25342 15.69471 1.000 23.96932  ? 124 THR   A CG2  1 
ATOM   1893 H H    . THR   A 1 127 ? 45.53118 -13.99596 13.52531 1.000 27.97423  ? 124 THR   A H    1 
ATOM   1894 H HA   . THR   A 1 127 ? 46.79546 -15.53875 15.36451 1.000 23.67048  ? 124 THR   A HA   1 
ATOM   1895 H HB   . THR   A 1 127 ? 47.93991 -13.43362 15.07508 1.000 29.23951  ? 124 THR   A HB   1 
ATOM   1896 H HG1  . THR   A 1 127 ? 48.03052 -14.58946 17.01167 1.000 26.35932  ? 124 THR   A HG1  1 
ATOM   1897 H HG21 . THR   A 1 127 ? 46.98843 -11.49545 15.76137 1.000 28.69755  ? 124 THR   A HG21 1 
ATOM   1898 H HG22 . THR   A 1 127 ? 45.86490 -12.17049 14.88130 1.000 28.69755  ? 124 THR   A HG22 1 
ATOM   1899 H HG23 . THR   A 1 127 ? 45.78607 -12.24643 16.45627 1.000 28.69755  ? 124 THR   A HG23 1 
ATOM   1900 N N    . THR   A 1 128 ? 45.03720 -15.21098 17.14980 1.000 20.73199  ? 125 THR   A N    1 
ATOM   1901 C CA   . THR   A 1 128 ? 43.87589 -15.26153 18.01974 1.000 21.39668  ? 125 THR   A CA   1 
ATOM   1902 C C    . THR   A 1 128 ? 44.34215 -14.98796 19.44107 1.000 22.70218  ? 125 THR   A C    1 
ATOM   1903 O O    . THR   A 1 128 ? 45.53429 -14.79356 19.69949 1.000 20.33495  ? 125 THR   A O    1 
ATOM   1904 C CB   . THR   A 1 128 ? 43.16689 -16.62124 17.95007 1.000 24.11256  ? 125 THR   A CB   1 
ATOM   1905 O OG1  . THR   A 1 128 ? 43.96677 -17.61358 18.60672 1.000 23.21717  ? 125 THR   A OG1  1 
ATOM   1906 C CG2  . THR   A 1 128 ? 42.92896 -17.04282 16.50805 1.000 23.23731  ? 125 THR   A CG2  1 
ATOM   1907 H H    . THR   A 1 128 ? 45.75079 -15.52373 17.51391 1.000 24.81276  ? 125 THR   A H    1 
ATOM   1908 H HA   . THR   A 1 128 ? 43.24961 -14.57577 17.73971 1.000 25.61038  ? 125 THR   A HA   1 
ATOM   1909 H HB   . THR   A 1 128 ? 42.30453 -16.55181 18.38872 1.000 28.86944  ? 125 THR   A HB   1 
ATOM   1910 H HG1  . THR   A 1 128 ? 43.96130 -17.48393 19.43663 1.000 27.79497  ? 125 THR   A HG1  1 
ATOM   1911 H HG21 . THR   A 1 128 ? 42.38724 -17.84706 16.48260 1.000 27.81915  ? 125 THR   A HG21 1 
ATOM   1912 H HG22 . THR   A 1 128 ? 42.46781 -16.33733 16.02793 1.000 27.81915  ? 125 THR   A HG22 1 
ATOM   1913 H HG23 . THR   A 1 128 ? 43.77614 -17.21993 16.07009 1.000 27.81915  ? 125 THR   A HG23 1 
ATOM   1914 N N    . HIS   A 1 129 ? 43.39872 -14.97212 20.37092 1.000 20.48493  ? 126 HIS   A N    1 
ATOM   1915 C CA   . HIS   A 1 129 ? 43.78045 -15.04665 21.76900 1.000 19.27451  ? 126 HIS   A CA   1 
ATOM   1916 C C    . HIS   A 1 129 ? 44.49505 -16.37531 22.00560 1.000 23.07384  ? 126 HIS   A C    1 
ATOM   1917 O O    . HIS   A 1 129 ? 44.13391 -17.38775 21.39337 1.000 19.89264  ? 126 HIS   A O    1 
ATOM   1918 C CB   . HIS   A 1 129 ? 42.55609 -14.93419 22.67545 1.000 23.17045  ? 126 HIS   A CB   1 
ATOM   1919 C CG   . HIS   A 1 129 ? 42.89527 -14.68270 24.11105 1.000 20.34813  ? 126 HIS   A CG   1 
ATOM   1920 N ND1  . HIS   A 1 129 ? 43.18401 -15.69810 24.99673 1.000 23.15378  ? 126 HIS   A ND1  1 
ATOM   1921 C CD2  . HIS   A 1 129 ? 43.00525 -13.52987 24.81241 1.000 27.03681  ? 126 HIS   A CD2  1 
ATOM   1922 C CE1  . HIS   A 1 129 ? 43.45206 -15.18256 26.18295 1.000 27.80625  ? 126 HIS   A CE1  1 
ATOM   1923 N NE2  . HIS   A 1 129 ? 43.35027 -13.86845 26.09833 1.000 24.99016  ? 126 HIS   A NE2  1 
ATOM   1924 H H    . HIS   A 1 129 ? 42.55326 -14.92022 20.22228 1.000 24.51629  ? 126 HIS   A H    1 
ATOM   1925 H HA   . HIS   A 1 129 ? 44.37548 -14.31472 21.99508 1.000 23.06379  ? 126 HIS   A HA   1 
ATOM   1926 H HB2  . HIS   A 1 129 ? 42.00550 -14.19753 22.36710 1.000 27.73892  ? 126 HIS   A HB2  1 
ATOM   1927 H HB3  . HIS   A 1 129 ? 42.05595 -15.76404 22.62959 1.000 27.73892  ? 126 HIS   A HB3  1 
ATOM   1928 H HD2  . HIS   A 1 129 ? 42.87212 -12.66968 24.48492 1.000 32.37854  ? 126 HIS   A HD2  1 
ATOM   1929 H HE1  . HIS   A 1 129 ? 43.67455 -15.66306 26.94749 1.000 33.30188  ? 126 HIS   A HE1  1 
ATOM   1930 H HE2  . HIS   A 1 129 ? 43.47908 -13.31462 26.74353 1.000 29.92256  ? 126 HIS   A HE2  1 
ATOM   1931 N N    . PRO   A 1 130 ? 45.51980 -16.41237 22.85763 1.000 25.04597  ? 127 PRO   A N    1 
ATOM   1932 C CA   . PRO   A 1 130 ? 46.21724 -17.68866 23.08816 1.000 24.91701  ? 127 PRO   A CA   1 
ATOM   1933 C C    . PRO   A 1 130 ? 45.28635 -18.82882 23.45834 1.000 23.65023  ? 127 PRO   A C    1 
ATOM   1934 O O    . PRO   A 1 130 ? 45.53353 -19.97537 23.06196 1.000 26.01187  ? 127 PRO   A O    1 
ATOM   1935 C CB   . PRO   A 1 130 ? 47.18555 -17.35371 24.22945 1.000 26.78206  ? 127 PRO   A CB   1 
ATOM   1936 C CG   . PRO   A 1 130 ? 47.43038 -15.88915 24.09361 1.000 31.97867  ? 127 PRO   A CG   1 
ATOM   1937 C CD   . PRO   A 1 130 ? 46.14084 -15.29944 23.59801 1.000 24.20322  ? 127 PRO   A CD   1 
ATOM   1938 H HA   . PRO   A 1 130 ? 46.72574 -17.93462 22.29960 1.000 29.83478  ? 127 PRO   A HA   1 
ATOM   1939 H HB2  . PRO   A 1 130 ? 46.77626 -17.56129 25.08402 1.000 32.07284  ? 127 PRO   A HB2  1 
ATOM   1940 H HB3  . PRO   A 1 130 ? 48.00862 -17.85626 24.12501 1.000 32.07284  ? 127 PRO   A HB3  1 
ATOM   1941 H HG2  . PRO   A 1 130 ? 47.66896 -15.51628 24.95671 1.000 38.30877  ? 127 PRO   A HG2  1 
ATOM   1942 H HG3  . PRO   A 1 130 ? 48.14544 -15.73508 23.45654 1.000 38.30877  ? 127 PRO   A HG3  1 
ATOM   1943 H HD2  . PRO   A 1 130 ? 45.58021 -15.02321 24.33983 1.000 28.97824  ? 127 PRO   A HD2  1 
ATOM   1944 H HD3  . PRO   A 1 130 ? 46.30923 -14.54591 23.01086 1.000 28.97824  ? 127 PRO   A HD3  1 
ATOM   1945 N N    . LEU   A 1 131 ? 44.21134 -18.54643 24.19655 1.000 21.55448  ? 128 LEU   A N    1 
ATOM   1946 C CA   . LEU   A 1 131 ? 43.27834 -19.58624 24.61036 1.000 26.56732  ? 128 LEU   A CA   1 
ATOM   1947 C C    . LEU   A 1 131 ? 42.41583 -20.09685 23.46563 1.000 27.19580  ? 128 LEU   A C    1 
ATOM   1948 O O    . LEU   A 1 131 ? 41.78200 -21.14631 23.61570 1.000 25.06642  ? 128 LEU   A O    1 
ATOM   1949 C CB   . LEU   A 1 131 ? 42.37973 -19.06357 25.73272 1.000 23.86246  ? 128 LEU   A CB   1 
ATOM   1950 C CG   . LEU   A 1 131 ? 43.07660 -18.74266 27.05663 1.000 36.76044  ? 128 LEU   A CG   1 
ATOM   1951 C CD1  . LEU   A 1 131 ? 42.08022 -18.18961 28.05923 1.000 37.56772  ? 128 LEU   A CD1  1 
ATOM   1952 C CD2  . LEU   A 1 131 ? 43.77044 -19.97593 27.61673 1.000 39.12916  ? 128 LEU   A CD2  1 
ATOM   1953 H H    . LEU   A 1 131 ? 44.00215 -17.75823 24.46967 1.000 25.79975  ? 128 LEU   A H    1 
ATOM   1954 H HA   . LEU   A 1 131 ? 43.78769 -20.33637 24.95500 1.000 31.81516  ? 128 LEU   A HA   1 
ATOM   1955 H HB2  . LEU   A 1 131 ? 41.95674 -18.24649 25.42554 1.000 28.56933  ? 128 LEU   A HB2  1 
ATOM   1956 H HB3  . LEU   A 1 131 ? 41.70607 -19.73627 25.91861 1.000 28.56933  ? 128 LEU   A HB3  1 
ATOM   1957 H HG   . LEU   A 1 131 ? 43.75467 -18.06740 26.89800 1.000 44.04691  ? 128 LEU   A HG   1 
ATOM   1958 H HD11 . LEU   A 1 131 ? 42.53536 -18.02783 28.90041 1.000 45.01564  ? 128 LEU   A HD11 1 
ATOM   1959 H HD12 . LEU   A 1 131 ? 41.71458 -17.35933 27.71596 1.000 45.01564  ? 128 LEU   A HD12 1 
ATOM   1960 H HD13 . LEU   A 1 131 ? 41.36880 -18.83647 28.18713 1.000 45.01564  ? 128 LEU   A HD13 1 
ATOM   1961 H HD21 . LEU   A 1 131 ? 44.03038 -19.80236 28.53499 1.000 46.88936  ? 128 LEU   A HD21 1 
ATOM   1962 H HD22 . LEU   A 1 131 ? 43.15668 -20.72630 27.58289 1.000 46.88936  ? 128 LEU   A HD22 1 
ATOM   1963 H HD23 . LEU   A 1 131 ? 44.55619 -20.16688 27.08098 1.000 46.88936  ? 128 LEU   A HD23 1 
ATOM   1964 N N    . ALA   A 1 132 ? 42.37335 -19.38999 22.33868 1.000 22.17314  ? 129 ALA   A N    1 
ATOM   1965 C CA   . ALA   A 1 132 ? 41.60024 -19.80983 21.17882 1.000 26.22458  ? 129 ALA   A CA   1 
ATOM   1966 C C    . ALA   A 1 132 ? 42.46296 -20.41574 20.07874 1.000 24.13936  ? 129 ALA   A C    1 
ATOM   1967 O O    . ALA   A 1 132 ? 41.93346 -20.77466 19.02236 1.000 23.83941  ? 129 ALA   A O    1 
ATOM   1968 C CB   . ALA   A 1 132 ? 40.81192 -18.62063 20.61825 1.000 22.55781  ? 129 ALA   A CB   1 
ATOM   1969 H H    . ALA   A 1 132 ? 42.79353 -18.64879 22.22174 1.000 26.54214  ? 129 ALA   A H    1 
ATOM   1970 H HA   . ALA   A 1 132 ? 40.96369 -20.48591 21.45919 1.000 31.40387  ? 129 ALA   A HA   1 
ATOM   1971 H HB1  . ALA   A 1 132 ? 40.29205 -18.91787 19.85517 1.000 27.00375  ? 129 ALA   A HB1  1 
ATOM   1972 H HB2  . ALA   A 1 132 ? 40.22145 -18.27974 21.30821 1.000 27.00375  ? 129 ALA   A HB2  1 
ATOM   1973 H HB3  . ALA   A 1 132 ? 41.43504 -17.92932 20.34493 1.000 27.00375  ? 129 ALA   A HB3  1 
ATOM   1974 N N    . LYS   A 1 133 ? 43.77235 -20.54759 20.30241 1.000 20.59108  ? 130 LYS   A N    1 
ATOM   1975 C CA   . LYS   A 1 133 ? 44.65966 -21.04203 19.25413 1.000 23.69539  ? 130 LYS   A CA   1 
ATOM   1976 C C    . LYS   A 1 133 ? 44.26509 -22.44488 18.80737 1.000 28.17895  ? 130 LYS   A C    1 
ATOM   1977 O O    . LYS   A 1 133 ? 44.08777 -22.70155 17.61031 1.000 22.01011  ? 130 LYS   A O    1 
ATOM   1978 C CB   . LYS   A 1 133 ? 46.10829 -21.02708 19.74506 1.000 27.87535  ? 130 LYS   A CB   1 
ATOM   1979 C CG   . LYS   A 1 133 ? 47.08908 -21.68182 18.78324 1.000 28.56798  ? 130 LYS   A CG   1 
ATOM   1980 C CD   . LYS   A 1 133 ? 48.51333 -21.61314 19.29962 1.000 33.08896  ? 130 LYS   A CD   1 
ATOM   1981 C CE   . LYS   A 1 133 ? 49.48462 -22.24018 18.31417 1.000 29.69053  ? 130 LYS   A CE   1 
ATOM   1982 N NZ   . LYS   A 1 133 ? 50.19977 -23.40692 18.89796 1.000 41.48589  ? 130 LYS   A NZ   1 
ATOM   1983 H H    . LYS   A 1 133 ? 44.16574 -20.35961 21.04370 1.000 24.64367  ? 130 LYS   A H    1 
ATOM   1984 H HA   . LYS   A 1 133 ? 44.58948 -20.45155 18.48778 1.000 28.36884  ? 130 LYS   A HA   1 
ATOM   1985 H HB2  . LYS   A 1 133 ? 46.38577 -20.10596 19.86933 1.000 33.38479  ? 130 LYS   A HB2  1 
ATOM   1986 H HB3  . LYS   A 1 133 ? 46.15669 -21.50473 20.58792 1.000 33.38479  ? 130 LYS   A HB3  1 
ATOM   1987 H HG2  . LYS   A 1 133 ? 46.85172 -22.61549 18.66994 1.000 34.21594  ? 130 LYS   A HG2  1 
ATOM   1988 H HG3  . LYS   A 1 133 ? 47.05341 -21.22437 17.92863 1.000 34.21594  ? 130 LYS   A HG3  1 
ATOM   1989 H HD2  . LYS   A 1 133 ? 48.76501 -20.68541 19.42955 1.000 39.64113  ? 130 LYS   A HD2  1 
ATOM   1990 H HD3  . LYS   A 1 133 ? 48.57558 -22.09452 20.13945 1.000 39.64113  ? 130 LYS   A HD3  1 
ATOM   1991 H HE2  . LYS   A 1 133 ? 48.99508 -22.54487 17.53415 1.000 35.56300  ? 130 LYS   A HE2  1 
ATOM   1992 H HE3  . LYS   A 1 133 ? 50.14556 -21.57963 18.05391 1.000 35.56300  ? 130 LYS   A HE3  1 
ATOM   1993 H HZ1  . LYS   A 1 133 ? 50.77117 -23.74221 18.30366 1.000 49.71744  ? 130 LYS   A HZ1  1 
ATOM   1994 H HZ2  . LYS   A 1 133 ? 50.65109 -23.15579 19.62276 1.000 49.71744  ? 130 LYS   A HZ2  1 
ATOM   1995 H HZ3  . LYS   A 1 133 ? 49.61600 -24.03891 19.12577 1.000 49.71744  ? 130 LYS   A HZ3  1 
ATOM   1996 N N    . ASP   A 1 134 ? 44.14499 -23.37511 19.75724 1.000 22.98091  ? 131 ASP   A N    1 
ATOM   1997 C CA   . ASP   A 1 134 ? 43.85643 -24.75984 19.39811 1.000 27.45237  ? 131 ASP   A CA   1 
ATOM   1998 C C    . ASP   A 1 134 ? 42.58035 -24.86187 18.57268 1.000 29.32344  ? 131 ASP   A C    1 
ATOM   1999 O O    . ASP   A 1 134 ? 42.52531 -25.60953 17.58911 1.000 29.73291  ? 131 ASP   A O    1 
ATOM   2000 C CB   . ASP   A 1 134 ? 43.74770 -25.61755 20.65877 1.000 34.77102  ? 131 ASP   A CB   1 
ATOM   2001 C CG   . ASP   A 1 134 ? 45.07002 -25.74946 21.39129 1.000 37.06005  ? 131 ASP   A CG   1 
ATOM   2002 O OD1  . ASP   A 1 134 ? 46.12730 -25.55146 20.75652 1.000 37.96400  ? 131 ASP   A OD1  1 
ATOM   2003 O OD2  . ASP   A 1 134 ? 45.05102 -26.05743 22.60126 1.000 50.07635  ? 131 ASP   A OD2  1 
ATOM   2004 H H    . ASP   A 1 134 ? 44.22485 -23.23161 20.60141 1.000 27.51146  ? 131 ASP   A H    1 
ATOM   2005 H HA   . ASP   A 1 134 ? 44.58956 -25.10201 18.86300 1.000 32.87722  ? 131 ASP   A HA   1 
ATOM   2006 H HB2  . ASP   A 1 134 ? 43.10814 -25.21086 21.26415 1.000 41.65960  ? 131 ASP   A HB2  1 
ATOM   2007 H HB3  . ASP   A 1 134 ? 43.45108 -26.50740 20.41161 1.000 41.65960  ? 131 ASP   A HB3  1 
ATOM   2008 N N    . LYS   A 1 135 ? 41.54243 -24.11767 18.95846 1.000 24.65315  ? 132 LYS   A N    1 
ATOM   2009 C CA   . LYS   A 1 135 ? 40.29553 -24.13753 18.20166 1.000 29.28243  ? 132 LYS   A CA   1 
ATOM   2010 C C    . LYS   A 1 135 ? 40.50744 -23.62537 16.78253 1.000 24.89388  ? 132 LYS   A C    1 
ATOM   2011 O O    . LYS   A 1 135 ? 40.01053 -24.21902 15.81800 1.000 22.05625  ? 132 LYS   A O    1 
ATOM   2012 C CB   . LYS   A 1 135 ? 39.23918 -23.29921 18.92496 1.000 35.32093  ? 132 LYS   A CB   1 
ATOM   2013 C CG   . LYS   A 1 135 ? 37.88545 -23.24417 18.22892 1.000 60.77873  ? 132 LYS   A CG   1 
ATOM   2014 C CD   . LYS   A 1 135 ? 36.82072 -23.99791 19.00963 1.000 97.32904  ? 132 LYS   A CD   1 
ATOM   2015 C CE   . LYS   A 1 135 ? 35.48960 -23.98390 18.27456 1.000 93.80605  ? 132 LYS   A CE   1 
ATOM   2016 N NZ   . LYS   A 1 135 ? 34.35253 -24.37806 19.15071 1.000 100.03887 ? 132 LYS   A NZ   1 
ATOM   2017 H H    . LYS   A 1 135 ? 41.53582 -23.60030 19.64539 1.000 29.51815  ? 132 LYS   A H    1 
ATOM   2018 H HA   . LYS   A 1 135 ? 39.97190 -25.05022 18.14550 1.000 35.07329  ? 132 LYS   A HA   1 
ATOM   2019 H HB2  . LYS   A 1 135 ? 39.09872 -23.67533 19.80797 1.000 42.31949  ? 132 LYS   A HB2  1 
ATOM   2020 H HB3  . LYS   A 1 135 ? 39.56634 -22.38915 19.00021 1.000 42.31949  ? 132 LYS   A HB3  1 
ATOM   2021 H HG2  . LYS   A 1 135 ? 37.60461 -22.31935 18.14684 1.000 72.86885  ? 132 LYS   A HG2  1 
ATOM   2022 H HG3  . LYS   A 1 135 ? 37.96039 -23.64739 17.34988 1.000 72.86885  ? 132 LYS   A HG3  1 
ATOM   2023 H HD2  . LYS   A 1 135 ? 37.09745 -24.92043 19.12491 1.000 116.72922 ? 132 LYS   A HD2  1 
ATOM   2024 H HD3  . LYS   A 1 135 ? 36.69725 -23.57794 19.87523 1.000 116.72922 ? 132 LYS   A HD3  1 
ATOM   2025 H HE2  . LYS   A 1 135 ? 35.31868 -23.08803 17.94425 1.000 112.50163 ? 132 LYS   A HE2  1 
ATOM   2026 H HE3  . LYS   A 1 135 ? 35.52942 -24.60869 17.53365 1.000 112.50163 ? 132 LYS   A HE3  1 
ATOM   2027 H HZ1  . LYS   A 1 135 ? 33.59832 -24.40102 18.67875 1.000 119.98102 ? 132 LYS   A HZ1  1 
ATOM   2028 H HZ2  . LYS   A 1 135 ? 34.50078 -25.18412 19.49768 1.000 119.98102 ? 132 LYS   A HZ2  1 
ATOM   2029 H HZ3  . LYS   A 1 135 ? 34.26093 -23.79083 19.81319 1.000 119.98102 ? 132 LYS   A HZ3  1 
ATOM   2030 N N    . MET   A 1 136 ? 41.24436 -22.52192 16.63616 1.000 24.25064  ? 133 MET   A N    1 
ATOM   2031 C CA   . MET   A 1 136 ? 41.45994 -21.94097 15.31580 1.000 24.18669  ? 133 MET   A CA   1 
ATOM   2032 C C    . MET   A 1 136 ? 42.25584 -22.87320 14.41213 1.000 26.62376  ? 133 MET   A C    1 
ATOM   2033 O O    . MET   A 1 136 ? 42.04526 -22.88807 13.19370 1.000 23.29772  ? 133 MET   A O    1 
ATOM   2034 C CB   . MET   A 1 136 ? 42.18770 -20.60228 15.45302 1.000 23.40377  ? 133 MET   A CB   1 
ATOM   2035 C CG   . MET   A 1 136 ? 42.25682 -19.79435 14.16926 1.000 20.17112  ? 133 MET   A CG   1 
ATOM   2036 S SD   . MET   A 1 136 ? 40.64483 -19.12999 13.73400 1.000 24.88245  ? 133 MET   A SD   1 
ATOM   2037 C CE   . MET   A 1 136 ? 41.00908 -18.31263 12.18510 1.000 23.37142  ? 133 MET   A CE   1 
ATOM   2038 H H    . MET   A 1 136 ? 41.62545 -22.09653 17.27913 1.000 29.03514  ? 133 MET   A H    1 
ATOM   2039 H HA   . MET   A 1 136 ? 40.59498 -21.77765 14.90828 1.000 28.95840  ? 133 MET   A HA   1 
ATOM   2040 H HB2  . MET   A 1 136 ? 41.72465 -20.06438 16.11418 1.000 28.01890  ? 133 MET   A HB2  1 
ATOM   2041 H HB3  . MET   A 1 136 ? 43.09774 -20.77272 15.74231 1.000 28.01890  ? 133 MET   A HB3  1 
ATOM   2042 H HG2  . MET   A 1 136 ? 42.87215 -19.05385 14.28726 1.000 24.13972  ? 133 MET   A HG2  1 
ATOM   2043 H HG3  . MET   A 1 136 ? 42.55917 -20.36482 13.44535 1.000 24.13972  ? 133 MET   A HG3  1 
ATOM   2044 H HE1  . MET   A 1 136 ? 40.18071 -17.99403 11.79370 1.000 27.98008  ? 133 MET   A HE1  1 
ATOM   2045 H HE2  . MET   A 1 136 ? 41.60376 -17.56528 12.35461 1.000 27.98008  ? 133 MET   A HE2  1 
ATOM   2046 H HE3  . MET   A 1 136 ? 41.43570 -18.94568 11.58665 1.000 27.98008  ? 133 MET   A HE3  1 
ATOM   2047 N N    . MET   A 1 137 ? 43.16813 -23.65258 14.98354 1.000 23.95007  ? 134 MET   A N    1 
ATOM   2048 C CA   . MET   A 1 137 ? 44.10076 -24.45860 14.21004 1.000 27.05303  ? 134 MET   A CA   1 
ATOM   2049 C C    . MET   A 1 137 ? 43.60339 -25.87327 13.95370 1.000 26.78761  ? 134 MET   A C    1 
ATOM   2050 O O    . MET   A 1 137 ? 44.34403 -26.67778 13.37849 1.000 27.38595  ? 134 MET   A O    1 
ATOM   2051 C CB   . MET   A 1 137 ? 45.45252 -24.51196 14.92766 1.000 25.16575  ? 134 MET   A CB   1 
ATOM   2052 C CG   . MET   A 1 137 ? 46.19795 -23.18981 14.91585 1.000 25.04498  ? 134 MET   A CG   1 
ATOM   2053 S SD   . MET   A 1 137 ? 46.59729 -22.64493 13.24464 1.000 27.16834  ? 134 MET   A SD   1 
ATOM   2054 C CE   . MET   A 1 137 ? 47.67655 -23.97031 12.70683 1.000 30.04369  ? 134 MET   A CE   1 
ATOM   2055 H H    . MET   A 1 137 ? 43.26718 -23.73182 15.83413 1.000 28.67446  ? 134 MET   A H    1 
ATOM   2056 H HA   . MET   A 1 137 ? 44.23389 -24.02919 13.35052 1.000 32.39801  ? 134 MET   A HA   1 
ATOM   2057 H HB2  . MET   A 1 137 ? 45.30539 -24.76174 15.85333 1.000 30.13327  ? 134 MET   A HB2  1 
ATOM   2058 H HB3  . MET   A 1 137 ? 46.01252 -25.17259 14.49077 1.000 30.13327  ? 134 MET   A HB3  1 
ATOM   2059 H HG2  . MET   A 1 137 ? 45.64516 -22.50953 15.33124 1.000 29.98835  ? 134 MET   A HG2  1 
ATOM   2060 H HG3  . MET   A 1 137 ? 47.02815 -23.28858 15.40770 1.000 29.98835  ? 134 MET   A HG3  1 
ATOM   2061 H HE1  . MET   A 1 137 ? 48.03858 -23.74855 11.83467 1.000 35.98680  ? 134 MET   A HE1  1 
ATOM   2062 H HE2  . MET   A 1 137 ? 48.39719 -24.07074 13.34831 1.000 35.98680  ? 134 MET   A HE2  1 
ATOM   2063 H HE3  . MET   A 1 137 ? 47.16453 -24.79241 12.65314 1.000 35.98680  ? 134 MET   A HE3  1 
ATOM   2064 N N    . ASN   A 1 138 ? 42.37696 -26.19609 14.35831 1.000 27.41031  ? 135 ASN   A N    1 
ATOM   2065 C CA   . ASN   A 1 138 ? 41.82925 -27.52315 14.11529 1.000 28.19229  ? 135 ASN   A CA   1 
ATOM   2066 C C    . ASN   A 1 138 ? 41.76972 -27.78553 12.61607 1.000 25.82841  ? 135 ASN   A C    1 
ATOM   2067 O O    . ASN   A 1 138 ? 41.00932 -27.13072 11.89546 1.000 24.17685  ? 135 ASN   A O    1 
ATOM   2068 C CB   . ASN   A 1 138 ? 40.44382 -27.65368 14.74895 1.000 31.23116  ? 135 ASN   A CB   1 
ATOM   2069 C CG   . ASN   A 1 138 ? 39.90303 -29.06628 14.67917 1.000 40.10098  ? 135 ASN   A CG   1 
ATOM   2070 O OD1  . ASN   A 1 138 ? 40.62977 -30.00629 14.36096 1.000 49.65327  ? 135 ASN   A OD1  1 
ATOM   2071 N ND2  . ASN   A 1 138 ? 38.62094 -29.22388 14.98284 1.000 56.89120  ? 135 ASN   A ND2  1 
ATOM   2072 H H    . ASN   A 1 138 ? 41.84491 -25.66393 14.77462 1.000 32.82674  ? 135 ASN   A H    1 
ATOM   2073 H HA   . ASN   A 1 138 ? 42.39705 -28.19588 14.52264 1.000 33.76512  ? 135 ASN   A HA   1 
ATOM   2074 H HB2  . ASN   A 1 138 ? 40.49744 -27.39810 15.68314 1.000 37.41177  ? 135 ASN   A HB2  1 
ATOM   2075 H HB3  . ASN   A 1 138 ? 39.82522 -27.07147 14.28069 1.000 37.41177  ? 135 ASN   A HB3  1 
ATOM   2076 H HD21 . ASN   A 1 138 ? 38.26630 -30.00696 14.95814 1.000 68.20382  ? 135 ASN   A HD21 1 
ATOM   2077 H HD22 . ASN   A 1 138 ? 38.14466 -28.54293 15.20436 1.000 68.20382  ? 135 ASN   A HD22 1 
ATOM   2078 N N    . GLY   A 1 139 ? 42.57880 -28.73086 12.13765 1.000 24.46586  ? 136 GLY   A N    1 
ATOM   2079 C CA   . GLY   A 1 139 ? 42.65251 -29.05558 10.72974 1.000 23.03480  ? 136 GLY   A CA   1 
ATOM   2080 C C    . GLY   A 1 139 ? 43.83876 -28.45828 10.00113 1.000 25.00232  ? 136 GLY   A C    1 
ATOM   2081 O O    . GLY   A 1 139 ? 44.14137 -28.89456 8.88273  1.000 24.89467  ? 136 GLY   A O    1 
ATOM   2082 H H    A GLY   A 1 139 ? 43.10392 -29.20453 12.62703 0.550 29.29340  ? 136 GLY   A H    1 
ATOM   2083 H H    B GLY   A 1 139 ? 43.10392 -29.20453 12.62703 0.450 29.29340  ? 136 GLY   A H    1 
ATOM   2084 H HA2  . GLY   A 1 139 ? 42.70192 -30.01970 10.63523 1.000 27.57614  ? 136 GLY   A HA2  1 
ATOM   2085 H HA3  . GLY   A 1 139 ? 41.84651 -28.73650 10.29449 1.000 27.57614  ? 136 GLY   A HA3  1 
ATOM   2086 N N    . GLY   A 1 140 ? 44.51584 -27.47885 10.59399 1.000 20.29414  ? 137 GLY   A N    1 
ATOM   2087 C CA   . GLY   A 1 140 ? 45.66549 -26.87403 9.94892  1.000 22.96733  ? 137 GLY   A CA   1 
ATOM   2088 C C    . GLY   A 1 140 ? 45.32647 -26.01795 8.75041  1.000 23.82500  ? 137 GLY   A C    1 
ATOM   2089 O O    . GLY   A 1 140 ? 46.13450 -25.91521 7.82266  1.000 24.94261  ? 137 GLY   A O    1 
ATOM   2090 H H    . GLY   A 1 140 ? 44.32758 -27.15075 11.36633 1.000 24.28734  ? 137 GLY   A H    1 
ATOM   2091 H HA2  . GLY   A 1 140 ? 46.12804 -26.31543 10.59306 1.000 27.49517  ? 137 GLY   A HA2  1 
ATOM   2092 H HA3  . GLY   A 1 140 ? 46.26449 -27.57731 9.65311  1.000 27.49517  ? 137 GLY   A HA3  1 
ATOM   2093 N N    . HIS   A 1 141 ? 44.15266 -25.38704 8.74817  1.000 20.09212  ? 138 HIS   A N    1 
ATOM   2094 C CA   . HIS   A 1 141 ? 43.70599 -24.60945 7.59875  1.000 19.06602  ? 138 HIS   A CA   1 
ATOM   2095 C C    . HIS   A 1 141 ? 44.29171 -23.20462 7.56033  1.000 23.24776  ? 138 HIS   A C    1 
ATOM   2096 O O    . HIS   A 1 141 ? 44.20100 -22.54337 6.51974  1.000 28.57418  ? 138 HIS   A O    1 
ATOM   2097 C CB   . HIS   A 1 141 ? 42.17749 -24.53707 7.59108  1.000 23.13679  ? 138 HIS   A CB   1 
ATOM   2098 C CG   . HIS   A 1 141 ? 41.51734 -25.86772 7.40719  1.000 23.49249  ? 138 HIS   A CG   1 
ATOM   2099 N ND1  . HIS   A 1 141 ? 41.57371 -26.56643 6.22033  1.000 25.27648  ? 138 HIS   A ND1  1 
ATOM   2100 C CD2  . HIS   A 1 141 ? 40.79739 -26.63337 8.26065  1.000 25.62043  ? 138 HIS   A CD2  1 
ATOM   2101 C CE1  . HIS   A 1 141 ? 40.91243 -27.70276 6.34898  1.000 25.07042  ? 138 HIS   A CE1  1 
ATOM   2102 N NE2  . HIS   A 1 141 ? 40.43116 -27.76755 7.57735  1.000 30.95021  ? 138 HIS   A NE2  1 
ATOM   2103 H H    . HIS   A 1 141 ? 43.59603 -25.39512 9.40368  1.000 24.04492  ? 138 HIS   A H    1 
ATOM   2104 H HA   . HIS   A 1 141 ? 43.98958 -25.05921 6.78745  1.000 22.81360  ? 138 HIS   A HA   1 
ATOM   2105 H HB2  . HIS   A 1 141 ? 41.87743 -24.17109 8.43779  1.000 27.69852  ? 138 HIS   A HB2  1 
ATOM   2106 H HB3  . HIS   A 1 141 ? 41.89523 -23.96224 6.86252  1.000 27.69852  ? 138 HIS   A HB3  1 
ATOM   2107 H HD2  . HIS   A 1 141 ? 40.58966 -26.42969 9.14398  1.000 30.67889  ? 138 HIS   A HD2  1 
ATOM   2108 H HE1  . HIS   A 1 141 ? 40.80418 -28.34732 5.68738  1.000 30.01887  ? 138 HIS   A HE1  1 
ATOM   2109 H HE2  . HIS   A 1 141 ? 39.96420 -28.41488 7.89753  0.252 37.07462  ? 138 HIS   A HE2  1 
ATOM   2110 N N    . TYR   A 1 142 ? 44.88852 -22.73786 8.65319  1.000 20.60841  ? 139 TYR   A N    1 
ATOM   2111 C CA   . TYR   A 1 142 ? 45.55201 -21.44509 8.70221  1.000 22.12897  ? 139 TYR   A CA   1 
ATOM   2112 C C    . TYR   A 1 142 ? 46.97270 -21.63661 9.21355  1.000 23.07056  ? 139 TYR   A C    1 
ATOM   2113 O O    . TYR   A 1 142 ? 47.33443 -22.69466 9.73481  1.000 23.49869  ? 139 TYR   A O    1 
ATOM   2114 C CB   . TYR   A 1 142 ? 44.80989 -20.45421 9.61307  1.000 21.44991  ? 139 TYR   A CB   1 
ATOM   2115 C CG   . TYR   A 1 142 ? 43.33139 -20.31695 9.33181  1.000 24.25330  ? 139 TYR   A CG   1 
ATOM   2116 C CD1  . TYR   A 1 142 ? 42.40758 -21.13030 9.96924  1.000 21.98738  ? 139 TYR   A CD1  1 
ATOM   2117 C CD2  . TYR   A 1 142 ? 42.85893 -19.36384 8.44252  1.000 24.00921  ? 139 TYR   A CD2  1 
ATOM   2118 C CE1  . TYR   A 1 142 ? 41.05737 -21.00701 9.72128  1.000 21.41010  ? 139 TYR   A CE1  1 
ATOM   2119 C CE2  . TYR   A 1 142 ? 41.50954 -19.23280 8.18852  1.000 22.57766  ? 139 TYR   A CE2  1 
ATOM   2120 C CZ   . TYR   A 1 142 ? 40.61249 -20.05549 8.83195  1.000 22.17310  ? 139 TYR   A CZ   1 
ATOM   2121 O OH   . TYR   A 1 142 ? 39.26521 -19.92850 8.58216  1.000 27.42647  ? 139 TYR   A OH   1 
ATOM   2122 H H    A TYR   A 1 142 ? 44.92165 -23.16618 9.39820  0.530 24.66447  ? 139 TYR   A H    1 
ATOM   2123 H H    B TYR   A 1 142 ? 44.92165 -23.16618 9.39820  0.470 24.66447  ? 139 TYR   A H    1 
ATOM   2124 H HA   . TYR   A 1 142 ? 45.58121 -21.07369 7.80661  1.000 26.48914  ? 139 TYR   A HA   1 
ATOM   2125 H HB2  . TYR   A 1 142 ? 44.90537 -20.75028 10.53183 1.000 25.67427  ? 139 TYR   A HB2  1 
ATOM   2126 H HB3  . TYR   A 1 142 ? 45.20983 -19.57728 9.50383  1.000 25.67427  ? 139 TYR   A HB3  1 
ATOM   2127 H HD1  . TYR   A 1 142 ? 42.70408 -21.77061 10.57502 1.000 26.31923  ? 139 TYR   A HD1  1 
ATOM   2128 H HD2  . TYR   A 1 142 ? 43.46205 -18.80343 8.00999  1.000 28.74543  ? 139 TYR   A HD2  1 
ATOM   2129 H HE1  . TYR   A 1 142 ? 40.45013 -21.56387 10.15265 1.000 25.62649  ? 139 TYR   A HE1  1 
ATOM   2130 H HE2  . TYR   A 1 142 ? 41.20730 -18.59218 7.58588  1.000 27.02756  ? 139 TYR   A HE2  1 
ATOM   2131 H HH   . TYR   A 1 142 ? 39.12737 -19.27191 8.07669  1.000 32.84614  ? 139 TYR   A HH   1 
ATOM   2132 N N    . THR   A 1 143 ? 47.77840 -20.59235 9.06176  1.000 23.30667  ? 140 THR   A N    1 
ATOM   2133 C CA   . THR   A 1 143 ? 49.10222 -20.51776 9.66232  1.000 24.81484  ? 140 THR   A CA   1 
ATOM   2134 C C    . THR   A 1 143 ? 49.04105 -19.53726 10.82425 1.000 25.81648  ? 140 THR   A C    1 
ATOM   2135 O O    . THR   A 1 143 ? 48.54744 -18.41543 10.66904 1.000 26.56403  ? 140 THR   A O    1 
ATOM   2136 C CB   . THR   A 1 143 ? 50.15026 -20.08093 8.63811  1.000 32.03860  ? 140 THR   A CB   1 
ATOM   2137 O OG1  . THR   A 1 143 ? 50.24066 -21.06594 7.60165  1.000 31.39122  ? 140 THR   A OG1  1 
ATOM   2138 C CG2  . THR   A 1 143 ? 51.50944 -19.91911 9.29656  1.000 28.93363  ? 140 THR   A CG2  1 
ATOM   2139 H H    . THR   A 1 143 ? 47.57330 -19.89529 8.60172  1.000 27.90237  ? 140 THR   A H    1 
ATOM   2140 H HA   . THR   A 1 143 ? 49.37036 -21.38743 9.99802  1.000 29.71218  ? 140 THR   A HA   1 
ATOM   2141 H HB   . THR   A 1 143 ? 49.89405 -19.22676 8.25647  1.000 38.38070  ? 140 THR   A HB   1 
ATOM   2142 H HG1  . THR   A 1 143 ? 50.37948 -21.82362 7.93670  1.000 37.60384  ? 140 THR   A HG1  1 
ATOM   2143 H HG21 . THR   A 1 143 ? 52.20015 -19.84977 8.61905  1.000 34.65473  ? 140 THR   A HG21 1 
ATOM   2144 H HG22 . THR   A 1 143 ? 51.52085 -19.11643 9.84105  1.000 34.65473  ? 140 THR   A HG22 1 
ATOM   2145 H HG23 . THR   A 1 143 ? 51.69793 -20.68511 9.86102  1.000 34.65473  ? 140 THR   A HG23 1 
ATOM   2146 N N    . TYR   A 1 144 ? 49.53071 -19.96084 11.98370 1.000 23.40677  ? 141 TYR   A N    1 
ATOM   2147 C CA   . TYR   A 1 144 ? 49.34023 -19.19792 13.20654 1.000 26.74406  ? 141 TYR   A CA   1 
ATOM   2148 C C    . TYR   A 1 144 ? 50.46418 -18.19346 13.41612 1.000 27.32195  ? 141 TYR   A C    1 
ATOM   2149 O O    . TYR   A 1 144 ? 51.63419 -18.47980 13.14636 1.000 29.29390  ? 141 TYR   A O    1 
ATOM   2150 C CB   . TYR   A 1 144 ? 49.25079 -20.12642 14.41686 1.000 20.83523  ? 141 TYR   A CB   1 
ATOM   2151 C CG   . TYR   A 1 144 ? 48.63163 -19.45124 15.61530 1.000 24.11798  ? 141 TYR   A CG   1 
ATOM   2152 C CD1  . TYR   A 1 144 ? 47.26237 -19.23811 15.67841 1.000 23.20210  ? 141 TYR   A CD1  1 
ATOM   2153 C CD2  . TYR   A 1 144 ? 49.41299 -19.00936 16.67249 1.000 24.81194  ? 141 TYR   A CD2  1 
ATOM   2154 C CE1  . TYR   A 1 144 ? 46.68558 -18.61316 16.76408 1.000 26.14328  ? 141 TYR   A CE1  1 
ATOM   2155 C CE2  . TYR   A 1 144 ? 48.84461 -18.38134 17.76662 1.000 26.25168  ? 141 TYR   A CE2  1 
ATOM   2156 C CZ   . TYR   A 1 144 ? 47.47993 -18.18683 17.80568 1.000 27.10359  ? 141 TYR   A CZ   1 
ATOM   2157 O OH   . TYR   A 1 144 ? 46.90355 -17.56532 18.88779 1.000 28.06247  ? 141 TYR   A OH   1 
ATOM   2158 H H    . TYR   A 1 144 ? 49.97738 -20.68855 12.08627 1.000 28.02249  ? 141 TYR   A H    1 
ATOM   2159 H HA   . TYR   A 1 144 ? 48.50969 -18.70255 13.13090 1.000 32.02724  ? 141 TYR   A HA   1 
ATOM   2160 H HB2  . TYR   A 1 144 ? 48.70454 -20.89449 14.18753 1.000 24.93665  ? 141 TYR   A HB2  1 
ATOM   2161 H HB3  . TYR   A 1 144 ? 50.14384 -20.41556 14.66130 1.000 24.93665  ? 141 TYR   A HB3  1 
ATOM   2162 H HD1  . TYR   A 1 144 ? 46.72340 -19.52189 14.97564 1.000 27.77689  ? 141 TYR   A HD1  1 
ATOM   2163 H HD2  . TYR   A 1 144 ? 50.33377 -19.13721 16.64560 1.000 29.70871  ? 141 TYR   A HD2  1 
ATOM   2164 H HE1  . TYR   A 1 144 ? 45.76557 -18.48030 16.79285 1.000 31.30630  ? 141 TYR   A HE1  1 
ATOM   2165 H HE2  . TYR   A 1 144 ? 49.37915 -18.09244 18.47069 1.000 31.43639  ? 141 TYR   A HE2  1 
ATOM   2166 H HH   . TYR   A 1 144 ? 46.07274 -17.50862 18.77765 1.000 33.60934  ? 141 TYR   A HH   1 
ATOM   2167 N N    A SER   A 1 145 ? 50.09096 -17.01004 13.89644 0.773 27.63865  ? 142 SER   A N    1 
ATOM   2168 N N    B SER   A 1 145 ? 50.09937 -17.01142 13.90779 0.227 27.19345  ? 142 SER   A N    1 
ATOM   2169 C CA   A SER   A 1 145 ? 51.02662 -15.94500 14.21554 0.773 28.04678  ? 142 SER   A CA   1 
ATOM   2170 C CA   B SER   A 1 145 ? 51.05254 -15.95243 14.20330 0.227 27.40181  ? 142 SER   A CA   1 
ATOM   2171 C C    A SER   A 1 145 ? 50.79452 -15.48860 15.64770 0.773 25.68309  ? 142 SER   A C    1 
ATOM   2172 C C    B SER   A 1 145 ? 50.79528 -15.42251 15.60514 0.227 26.18764  ? 142 SER   A C    1 
ATOM   2173 O O    A SER   A 1 145 ? 49.67116 -15.53535 16.15618 0.773 27.19433  ? 142 SER   A O    1 
ATOM   2174 O O    B SER   A 1 145 ? 49.64602 -15.35526 16.05151 0.227 26.73378  ? 142 SER   A O    1 
ATOM   2175 C CB   A SER   A 1 145 ? 50.86831 -14.75259 13.26234 0.773 26.79449  ? 142 SER   A CB   1 
ATOM   2176 C CB   B SER   A 1 145 ? 50.95093 -14.80814 13.18865 0.227 26.89831  ? 142 SER   A CB   1 
ATOM   2177 O OG   A SER   A 1 145 ? 51.60917 -13.63433 13.71839 0.773 24.45695  ? 142 SER   A OG   1 
ATOM   2178 O OG   B SER   A 1 145 ? 49.70654 -14.14035 13.29870 0.227 26.85966  ? 142 SER   A OG   1 
ATOM   2179 H H    A SER   A 1 145 ? 49.27219 -16.79644 14.05002 0.773 33.10075  ? 142 SER   A H    1 
ATOM   2180 H H    B SER   A 1 145 ? 49.28490 -16.79697 14.08174 0.227 32.56651  ? 142 SER   A H    1 
ATOM   2181 H HA   A SER   A 1 145 ? 51.93572 -16.27448 14.13888 0.773 33.59051  ? 142 SER   A HA   1 
ATOM   2182 H HA   B SER   A 1 145 ? 51.95442 -16.30781 14.16844 0.227 32.81654  ? 142 SER   A HA   1 
ATOM   2183 H HB2  A SER   A 1 145 ? 51.19091 -15.00690 12.38362 0.773 32.08776  ? 142 SER   A HB2  1 
ATOM   2184 H HB2  B SER   A 1 145 ? 51.66498 -14.17355 13.35693 0.227 32.21234  ? 142 SER   A HB2  1 
ATOM   2185 H HB3  A SER   A 1 145 ? 49.93027 -14.51040 13.21409 0.773 32.08776  ? 142 SER   A HB3  1 
ATOM   2186 H HB3  B SER   A 1 145 ? 51.03492 -15.17239 12.29357 0.227 32.21234  ? 142 SER   A HB3  1 
ATOM   2187 H HG   A SER   A 1 145 ? 51.44837 -12.96658 13.23481 0.773 29.28271  ? 142 SER   A HG   1 
ATOM   2188 H HG   B SER   A 1 145 ? 49.67983 -13.69834 14.01250 0.227 32.16597  ? 142 SER   A HG   1 
ATOM   2189 N N    . GLU   A 1 146 ? 51.87036 -15.04728 16.29516 1.000 23.14597  ? 143 GLU   A N    1 
ATOM   2190 C CA   A GLU   A 1 146 ? 51.79955 -14.48515 17.63586 0.424 30.88551  ? 143 GLU   A CA   1 
ATOM   2191 C CA   B GLU   A 1 146 ? 51.78423 -14.48245 17.63375 0.576 30.87628  ? 143 GLU   A CA   1 
ATOM   2192 C C    . GLU   A 1 146 ? 51.88196 -12.96270 17.63015 1.000 29.61428  ? 143 GLU   A C    1 
ATOM   2193 O O    . GLU   A 1 146 ? 52.00994 -12.35580 18.69833 1.000 29.37723  ? 143 GLU   A O    1 
ATOM   2194 C CB   A GLU   A 1 146 ? 52.91189 -15.06925 18.51214 0.424 34.02626  ? 143 GLU   A CB   1 
ATOM   2195 C CB   B GLU   A 1 146 ? 52.87500 -15.07971 18.52442 0.576 34.03644  ? 143 GLU   A CB   1 
ATOM   2196 C CG   A GLU   A 1 146 ? 52.82481 -16.58423 18.70755 0.424 41.48861  ? 143 GLU   A CG   1 
ATOM   2197 C CG   B GLU   A 1 146 ? 52.72836 -16.57830 18.73359 0.576 41.57741  ? 143 GLU   A CG   1 
ATOM   2198 C CD   A GLU   A 1 146 ? 52.33433 -16.99206 20.09097 0.424 43.36839  ? 143 GLU   A CD   1 
ATOM   2199 C CD   B GLU   A 1 146 ? 53.79224 -17.15249 19.64666 0.576 45.19304  ? 143 GLU   A CD   1 
ATOM   2200 O OE1  A GLU   A 1 146 ? 52.25132 -16.12792 20.98999 0.424 43.00507  ? 143 GLU   A OE1  1 
ATOM   2201 O OE1  B GLU   A 1 146 ? 54.50054 -16.36708 20.31123 0.576 45.54036  ? 143 GLU   A OE1  1 
ATOM   2202 O OE2  A GLU   A 1 146 ? 52.03403 -18.18977 20.27991 0.424 48.02990  ? 143 GLU   A OE2  1 
ATOM   2203 O OE2  B GLU   A 1 146 ? 53.91900 -18.39286 19.69850 0.576 48.76066  ? 143 GLU   A OE2  1 
ATOM   2204 H H    A GLU   A 1 146 ? 52.66637 -15.06442 15.97008 0.773 27.70954  ? 143 GLU   A H    1 
ATOM   2205 H HA   A GLU   A 1 146 ? 50.95055 -14.73522 18.03281 0.424 36.99698  ? 143 GLU   A HA   1 
ATOM   2206 H HA   B GLU   A 1 146 ? 50.92595 -14.72081 18.01772 0.576 36.98590  ? 143 GLU   A HA   1 
ATOM   2207 H HB2  A GLU   A 1 146 ? 53.76732 -14.87445 18.09839 0.424 40.76588  ? 143 GLU   A HB2  1 
ATOM   2208 H HB2  B GLU   A 1 146 ? 53.73850 -14.91949 18.11259 0.576 40.77811  ? 143 GLU   A HB2  1 
ATOM   2209 H HB3  A GLU   A 1 146 ? 52.86555 -14.65620 19.38858 0.424 40.76588  ? 143 GLU   A HB3  1 
ATOM   2210 H HB3  B GLU   A 1 146 ? 52.83799 -14.65245 19.39447 0.576 40.77811  ? 143 GLU   A HB3  1 
ATOM   2211 H HG2  A GLU   A 1 146 ? 52.20740 -16.94917 18.05445 0.424 49.72071  ? 143 GLU   A HG2  1 
ATOM   2212 H HG2  B GLU   A 1 146 ? 51.86263 -16.75809 19.13245 0.576 49.82726  ? 143 GLU   A HG2  1 
ATOM   2213 H HG3  A GLU   A 1 146 ? 53.70680 -16.96748 18.58065 0.424 49.72071  ? 143 GLU   A HG3  1 
ATOM   2214 H HG3  B GLU   A 1 146 ? 52.79744 -17.02503 17.87536 0.576 49.82726  ? 143 GLU   A HG3  1 
ATOM   2215 N N    . ASN   A 1 147 ? 51.82164 -12.33642 16.45630 1.000 27.44089  ? 144 ASN   A N    1 
ATOM   2216 C CA   . ASN   A 1 147 ? 51.82219 -10.88341 16.37959 1.000 25.74628  ? 144 ASN   A CA   1 
ATOM   2217 C C    . ASN   A 1 147 ? 50.54825 -10.32315 17.00267 1.000 27.27970  ? 144 ASN   A C    1 
ATOM   2218 O O    . ASN   A 1 147 ? 49.47784 -10.93452 16.94235 1.000 26.78283  ? 144 ASN   A O    1 
ATOM   2219 C CB   . ASN   A 1 147 ? 51.93457 -10.41760 14.92706 1.000 30.09371  ? 144 ASN   A CB   1 
ATOM   2220 C CG   . ASN   A 1 147 ? 53.35754 -10.46415 14.40314 1.000 34.41964  ? 144 ASN   A CG   1 
ATOM   2221 O OD1  . ASN   A 1 147 ? 54.31012 -10.62382 15.16588 1.000 36.69989  ? 144 ASN   A OD1  1 
ATOM   2222 N ND2  . ASN   A 1 147 ? 53.50823 -10.30632 13.09375 1.000 46.06138  ? 144 ASN   A ND2  1 
ATOM   2223 H H    . ASN   A 1 147 ? 51.77988 -12.73112 15.69337 1.000 32.86344  ? 144 ASN   A H    1 
ATOM   2224 H HA   . ASN   A 1 147 ? 52.58694 -10.53537 16.86428 1.000 30.82991  ? 144 ASN   A HA   1 
ATOM   2225 H HB2  . ASN   A 1 147 ? 51.39018 -10.99342 14.36762 1.000 36.04683  ? 144 ASN   A HB2  1 
ATOM   2226 H HB3  . ASN   A 1 147 ? 51.62172 -9.50161  14.86393 1.000 36.04683  ? 144 ASN   A HB3  1 
ATOM   2227 H HD21 . ASN   A 1 147 ? 54.29464 -10.32451 12.74614 1.000 55.20803  ? 144 ASN   A HD21 1 
ATOM   2228 H HD22 . ASN   A 1 147 ? 52.81946 -10.18587 12.59307 1.000 55.20803  ? 144 ASN   A HD22 1 
ATOM   2229 N N    . ARG   A 1 148 ? 50.67172 -9.14005  17.60608 1.000 23.40031  ? 145 ARG   A N    1 
ATOM   2230 C CA   . ARG   A 1 148 ? 49.52096 -8.53165  18.26569 1.000 26.64587  ? 145 ARG   A CA   1 
ATOM   2231 C C    . ARG   A 1 148 ? 48.43251 -8.18949  17.25893 1.000 25.68089  ? 145 ARG   A C    1 
ATOM   2232 O O    . ARG   A 1 148 ? 47.23871 -8.31744  17.55606 1.000 20.86422  ? 145 ARG   A O    1 
ATOM   2233 C CB   . ARG   A 1 148 ? 49.96184 -7.29100  19.03970 1.000 29.34687  ? 145 ARG   A CB   1 
ATOM   2234 C CG   . ARG   A 1 148 ? 50.92442 -7.60688  20.17410 1.000 30.39383  ? 145 ARG   A CG   1 
ATOM   2235 C CD   . ARG   A 1 148 ? 51.43211 -6.35128  20.85807 1.000 32.77940  ? 145 ARG   A CD   1 
ATOM   2236 N NE   . ARG   A 1 148 ? 50.35265 -5.54540  21.41658 1.000 32.06811  ? 145 ARG   A NE   1 
ATOM   2237 C CZ   . ARG   A 1 148 ? 49.77607 -5.76786  22.59056 1.000 30.58098  ? 145 ARG   A CZ   1 
ATOM   2238 N NH1  . ARG   A 1 148 ? 50.12354 -6.79430  23.34980 1.000 33.22666  ? 145 ARG   A NH1  1 
ATOM   2239 N NH2  . ARG   A 1 148 ? 48.82484 -4.93955  23.01312 1.000 36.18344  ? 145 ARG   A NH2  1 
ATOM   2240 H H    . ARG   A 1 148 ? 51.39657 -8.67901  17.64654 1.000 28.01474  ? 145 ARG   A H    1 
ATOM   2241 H HA   . ARG   A 1 148 ? 49.14816 -9.16100  18.90275 1.000 31.90941  ? 145 ARG   A HA   1 
ATOM   2242 H HB2  . ARG   A 1 148 ? 50.40747 -6.68205  18.43021 1.000 35.15062  ? 145 ARG   A HB2  1 
ATOM   2243 H HB3  . ARG   A 1 148 ? 49.17908 -6.86418  19.42183 1.000 35.15062  ? 145 ARG   A HB3  1 
ATOM   2244 H HG2  . ARG   A 1 148 ? 50.46923 -8.14930  20.83704 1.000 36.40697  ? 145 ARG   A HG2  1 
ATOM   2245 H HG3  . ARG   A 1 148 ? 51.68842 -8.08803  19.81958 1.000 36.40697  ? 145 ARG   A HG3  1 
ATOM   2246 H HD2  . ARG   A 1 148 ? 52.02595 -6.60262  21.58270 1.000 39.26966  ? 145 ARG   A HD2  1 
ATOM   2247 H HD3  . ARG   A 1 148 ? 51.90931 -5.80836  20.21122 1.000 39.26966  ? 145 ARG   A HD3  1 
ATOM   2248 H HE   . ARG   A 1 148 ? 50.06989 -4.87903  20.95225 1.000 38.41610  ? 145 ARG   A HE   1 
ATOM   2249 H HH11 . ARG   A 1 148 ? 50.73663 -7.33646  23.08564 1.000 39.80637  ? 145 ARG   A HH11 1 
ATOM   2250 H HH12 . ARG   A 1 148 ? 49.73628 -6.91929  24.10744 1.000 39.80637  ? 145 ARG   A HH12 1 
ATOM   2251 H HH21 . ARG   A 1 148 ? 48.59072 -4.26987  22.52701 1.000 43.35450  ? 145 ARG   A HH21 1 
ATOM   2252 H HH22 . ARG   A 1 148 ? 48.44398 -5.07374  23.77243 1.000 43.35450  ? 145 ARG   A HH22 1 
ATOM   2253 N N    . VAL   A 1 149 ? 48.82503 -7.74919  16.06632 1.000 25.66294  ? 146 VAL   A N    1 
ATOM   2254 C CA   . VAL   A 1 149 ? 47.92080 -7.58624  14.93611 1.000 25.25269  ? 146 VAL   A CA   1 
ATOM   2255 C C    . VAL   A 1 149 ? 48.53770 -8.30193  13.74463 1.000 23.61832  ? 146 VAL   A C    1 
ATOM   2256 O O    . VAL   A 1 149 ? 49.74319 -8.18537  13.49719 1.000 23.01336  ? 146 VAL   A O    1 
ATOM   2257 C CB   . VAL   A 1 149 ? 47.66653 -6.10343  14.59596 1.000 21.05360  ? 146 VAL   A CB   1 
ATOM   2258 C CG1  . VAL   A 1 149 ? 46.74660 -5.98877  13.38689 1.000 24.61015  ? 146 VAL   A CG1  1 
ATOM   2259 C CG2  . VAL   A 1 149 ? 47.07628 -5.37314  15.78570 1.000 26.33936  ? 146 VAL   A CG2  1 
ATOM   2260 H H    . VAL   A 1 149 ? 49.63688 -7.53199  15.88377 1.000 30.72990  ? 146 VAL   A H    1 
ATOM   2261 H HA   . VAL   A 1 149 ? 47.06553 -7.99083  15.14993 1.000 30.23760  ? 146 VAL   A HA   1 
ATOM   2262 H HB   . VAL   A 1 149 ? 48.51299 -5.68306  14.37758 1.000 25.19869  ? 146 VAL   A HB   1 
ATOM   2263 H HG11 . VAL   A 1 149 ? 46.49833 -5.05890  13.26602 1.000 29.46655  ? 146 VAL   A HG11 1 
ATOM   2264 H HG12 . VAL   A 1 149 ? 47.21589 -6.31063  12.60135 1.000 29.46655  ? 146 VAL   A HG12 1 
ATOM   2265 H HG13 . VAL   A 1 149 ? 45.95353 -6.52547  13.54145 1.000 29.46655  ? 146 VAL   A HG13 1 
ATOM   2266 H HG21 . VAL   A 1 149 ? 46.92607 -4.44576  15.54425 1.000 31.54160  ? 146 VAL   A HG21 1 
ATOM   2267 H HG22 . VAL   A 1 149 ? 46.23571 -5.79213  16.02818 1.000 31.54160  ? 146 VAL   A HG22 1 
ATOM   2268 H HG23 . VAL   A 1 149 ? 47.69810 -5.42504  16.52837 1.000 31.54160  ? 146 VAL   A HG23 1 
ATOM   2269 N N    . GLU   A 1 150 ? 47.71466 -9.04240  13.00856 1.000 27.33083  ? 147 GLU   A N    1 
ATOM   2270 C CA   . GLU   A 1 150 ? 48.16805 -9.76647  11.83023 1.000 22.63182  ? 147 GLU   A CA   1 
ATOM   2271 C C    . GLU   A 1 150 ? 47.24057 -9.44693  10.66929 1.000 24.52722  ? 147 GLU   A C    1 
ATOM   2272 O O    . GLU   A 1 150 ? 46.01541 -9.46214  10.82588 1.000 26.83738  ? 147 GLU   A O    1 
ATOM   2273 C CB   . GLU   A 1 150 ? 48.20812 -11.27845 12.08368 1.000 27.43974  ? 147 GLU   A CB   1 
ATOM   2274 C CG   . GLU   A 1 150 ? 48.93707 -12.05965 11.00229 1.000 30.90809  ? 147 GLU   A CG   1 
ATOM   2275 C CD   . GLU   A 1 150 ? 50.39070 -11.64670 10.86710 1.000 27.94405  ? 147 GLU   A CD   1 
ATOM   2276 O OE1  . GLU   A 1 150 ? 51.18952 -11.97340 11.76958 1.000 30.07533  ? 147 GLU   A OE1  1 
ATOM   2277 O OE2  . GLU   A 1 150 ? 50.72889 -10.97995 9.86679  1.000 36.56697  ? 147 GLU   A OE2  1 
ATOM   2278 H H    . GLU   A 1 150 ? 46.87688 -9.14105  13.17587 1.000 32.73137  ? 147 GLU   A H    1 
ATOM   2279 H HA   . GLU   A 1 150 ? 49.06403 -9.47838  11.59546 1.000 27.09255  ? 147 GLU   A HA   1 
ATOM   2280 H HB2  . GLU   A 1 150 ? 48.66256 -11.44196 12.92491 1.000 32.86206  ? 147 GLU   A HB2  1 
ATOM   2281 H HB3  . GLU   A 1 150 ? 47.29824 -11.61172 12.12788 1.000 32.86206  ? 147 GLU   A HB3  1 
ATOM   2282 H HG2  . GLU   A 1 150 ? 48.91168 -13.00414 11.22180 1.000 37.02408  ? 147 GLU   A HG2  1 
ATOM   2283 H HG3  . GLU   A 1 150 ? 48.49984 -11.90519 10.15031 1.000 37.02408  ? 147 GLU   A HG3  1 
ATOM   2284 N N    . LYS   A 1 151 ? 47.82781 -9.15179  9.51197  1.000 31.02019  ? 148 LYS   A N    1 
ATOM   2285 C CA   . LYS   A 1 151 ? 47.07770 -8.86054  8.29709  1.000 30.09485  ? 148 LYS   A CA   1 
ATOM   2286 C C    . LYS   A 1 151 ? 47.67879 -9.66678  7.15748  1.000 27.10145  ? 148 LYS   A C    1 
ATOM   2287 O O    . LYS   A 1 151 ? 48.85071 -9.48050  6.81286  1.000 31.72269  ? 148 LYS   A O    1 
ATOM   2288 C CB   . LYS   A 1 151 ? 47.10366 -7.36466  7.97078  1.000 32.51141  ? 148 LYS   A CB   1 
ATOM   2289 C CG   . LYS   A 1 151 ? 46.18355 -6.97196  6.82052  1.000 37.48099  ? 148 LYS   A CG   1 
ATOM   2290 C CD   . LYS   A 1 151 ? 46.24078 -5.47761  6.53502  1.000 43.46188  ? 148 LYS   A CD   1 
ATOM   2291 C CE   . LYS   A 1 151 ? 45.33705 -5.09400  5.37003  1.000 50.17647  ? 148 LYS   A CE   1 
ATOM   2292 N NZ   . LYS   A 1 151 ? 45.66131 -5.84495  4.12399  1.000 73.15290  ? 148 LYS   A NZ   1 
ATOM   2293 H H    A LYS   A 1 151 ? 48.68027 -9.11365  9.40492  0.340 37.15860  ? 148 LYS   A H    1 
ATOM   2294 H H    B LYS   A 1 151 ? 48.68027 -9.11365  9.40492  0.660 37.15860  ? 148 LYS   A H    1 
ATOM   2295 H HA   . LYS   A 1 151 ? 46.15286 -9.12873  8.41393  1.000 36.04819  ? 148 LYS   A HA   1 
ATOM   2296 H HB2  . LYS   A 1 151 ? 46.82401 -6.86912  8.75636  1.000 38.94806  ? 148 LYS   A HB2  1 
ATOM   2297 H HB3  . LYS   A 1 151 ? 48.00815 -7.11457  7.72535  1.000 38.94806  ? 148 LYS   A HB3  1 
ATOM   2298 H HG2  . LYS   A 1 151 ? 46.45450 -7.44486  6.01812  1.000 44.91156  ? 148 LYS   A HG2  1 
ATOM   2299 H HG3  . LYS   A 1 151 ? 45.26943 -7.20256  7.04880  1.000 44.91156  ? 148 LYS   A HG3  1 
ATOM   2300 H HD2  . LYS   A 1 151 ? 45.94849 -4.98940  7.32059  1.000 52.08863  ? 148 LYS   A HD2  1 
ATOM   2301 H HD3  . LYS   A 1 151 ? 47.15069 -5.22866  6.30921  1.000 52.08863  ? 148 LYS   A HD3  1 
ATOM   2302 H HE2  . LYS   A 1 151 ? 44.41618 -5.28675  5.60617  1.000 60.14613  ? 148 LYS   A HE2  1 
ATOM   2303 H HE3  . LYS   A 1 151 ? 45.44121 -4.14729  5.18621  1.000 60.14613  ? 148 LYS   A HE3  1 
ATOM   2304 H HZ1  . LYS   A 1 151 ? 46.52251 -5.74423  3.92328  1.000 87.71785  ? 148 LYS   A HZ1  1 
ATOM   2305 H HZ2  . LYS   A 1 151 ? 45.49053 -6.71102  4.23737  1.000 87.71785  ? 148 LYS   A HZ2  1 
ATOM   2306 H HZ3  . LYS   A 1 151 ? 45.16955 -5.53967  3.44791  1.000 87.71785  ? 148 LYS   A HZ3  1 
ATOM   2307 N N    . ASP   A 1 152 ? 46.88106 -10.56344 6.58309  1.000 30.85524  ? 149 ASP   A N    1 
ATOM   2308 C CA   . ASP   A 1 152 ? 47.29498 -11.38757 5.45213  1.000 31.95066  ? 149 ASP   A CA   1 
ATOM   2309 C C    . ASP   A 1 152 ? 46.20303 -11.29505 4.39734  1.000 40.61906  ? 149 ASP   A C    1 
ATOM   2310 O O    . ASP   A 1 152 ? 45.10054 -11.81728 4.59220  1.000 36.09489  ? 149 ASP   A O    1 
ATOM   2311 C CB   . ASP   A 1 152 ? 47.52880 -12.83761 5.87731  1.000 32.39226  ? 149 ASP   A CB   1 
ATOM   2312 C CG   . ASP   A 1 152 ? 48.20838 -13.66026 4.79923  1.000 32.33720  ? 149 ASP   A CG   1 
ATOM   2313 O OD1  . ASP   A 1 152 ? 48.69492 -13.06728 3.81423  1.000 36.83842  ? 149 ASP   A OD1  1 
ATOM   2314 O OD2  . ASP   A 1 152 ? 48.25565 -14.90098 4.93672  1.000 33.31913  ? 149 ASP   A OD2  1 
ATOM   2315 H H    . ASP   A 1 152 ? 46.07406 -10.71607 6.83817  1.000 36.96067  ? 149 ASP   A H    1 
ATOM   2316 H HA   . ASP   A 1 152 ? 48.12374 -11.04812 5.07953  1.000 38.27517  ? 149 ASP   A HA   1 
ATOM   2317 H HB2  . ASP   A 1 152 ? 48.09442 -12.84911 6.66524  1.000 38.80508  ? 149 ASP   A HB2  1 
ATOM   2318 H HB3  . ASP   A 1 152 ? 46.67408 -13.25079 6.07643  1.000 38.80508  ? 149 ASP   A HB3  1 
ATOM   2319 N N    . GLY   A 1 153 ? 46.49972 -10.62768 3.28822  1.000 52.03900  ? 150 GLY   A N    1 
ATOM   2320 C CA   . GLY   A 1 153 ? 45.49022 -10.42233 2.27104  1.000 70.42032  ? 150 GLY   A CA   1 
ATOM   2321 C C    . GLY   A 1 153 ? 44.37375 -9.54489  2.80324  1.000 38.36442  ? 150 GLY   A C    1 
ATOM   2322 O O    . GLY   A 1 153 ? 44.60841 -8.41997  3.25984  1.000 38.98740  ? 150 GLY   A O    1 
ATOM   2323 H H    . GLY   A 1 153 ? 47.26974 -10.28997 3.10760  1.000 62.38118  ? 150 GLY   A H    1 
ATOM   2324 H HA2  . GLY   A 1 153 ? 45.88636 -9.99200  1.49723  1.000 84.43875  ? 150 GLY   A HA2  1 
ATOM   2325 H HA3  . GLY   A 1 153 ? 45.11735 -11.27617 2.00119  1.000 84.43875  ? 150 GLY   A HA3  1 
ATOM   2326 N N    . LEU   A 1 154 ? 43.14802 -10.05831 2.76273  1.000 38.45566  ? 151 LEU   A N    1 
ATOM   2327 C CA   . LEU   A 1 154 ? 41.97690 -9.32979  3.22850  1.000 45.13744  ? 151 LEU   A CA   1 
ATOM   2328 C C    . LEU   A 1 154 ? 41.54711 -9.74817  4.63219  1.000 36.60192  ? 151 LEU   A C    1 
ATOM   2329 O O    . LEU   A 1 154 ? 40.46782 -9.35135  5.08440  1.000 30.05356  ? 151 LEU   A O    1 
ATOM   2330 C CB   . LEU   A 1 154 ? 40.82248 -9.51794  2.23707  1.000 49.33686  ? 151 LEU   A CB   1 
ATOM   2331 C CG   . LEU   A 1 154 ? 40.26112 -10.93447 2.07005  1.000 65.20553  ? 151 LEU   A CG   1 
ATOM   2332 C CD1  . LEU   A 1 154 ? 39.04584 -11.16201 2.95989  1.000 70.93107  ? 151 LEU   A CD1  1 
ATOM   2333 C CD2  . LEU   A 1 154 ? 39.90913 -11.20922 0.61012  1.000 51.75969  ? 151 LEU   A CD2  1 
ATOM   2334 H H    . LEU   A 1 154 ? 42.96741 -10.84389 2.46298  1.000 46.08117  ? 151 LEU   A H    1 
ATOM   2335 H HA   . LEU   A 1 154 ? 42.18820 -8.38366  3.26175  1.000 54.09930  ? 151 LEU   A HA   1 
ATOM   2336 H HB2  . LEU   A 1 154 ? 40.08692 -8.95629  2.52758  1.000 59.13861  ? 151 LEU   A HB2  1 
ATOM   2337 H HB3  . LEU   A 1 154 ? 41.13218 -9.23322  1.36304  1.000 59.13861  ? 151 LEU   A HB3  1 
ATOM   2338 H HG   . LEU   A 1 154 ? 40.94691 -11.56381 2.34303  1.000 78.18101  ? 151 LEU   A HG   1 
ATOM   2339 H HD11 . LEU   A 1 154 ? 38.24347 -11.11409 2.41693  1.000 85.05166  ? 151 LEU   A HD11 1 
ATOM   2340 H HD12 . LEU   A 1 154 ? 39.11511 -12.03777 3.37117  1.000 85.05166  ? 151 LEU   A HD12 1 
ATOM   2341 H HD13 . LEU   A 1 154 ? 39.02312 -10.47569 3.64498  1.000 85.05166  ? 151 LEU   A HD13 1 
ATOM   2342 H HD21 . LEU   A 1 154 ? 39.54547 -12.10543 0.53622  1.000 62.04600  ? 151 LEU   A HD21 1 
ATOM   2343 H HD22 . LEU   A 1 154 ? 39.25107 -10.55996 0.31635  1.000 62.04600  ? 151 LEU   A HD22 1 
ATOM   2344 H HD23 . LEU   A 1 154 ? 40.71243 -11.13278 0.07182  1.000 62.04600  ? 151 LEU   A HD23 1 
ATOM   2345 N N    . ILE   A 1 155 ? 42.37168 -10.52085 5.33578  1.000 30.07788  ? 152 ILE   A N    1 
ATOM   2346 C CA   . ILE   A 1 155 ? 42.04963 -11.02847 6.66567  1.000 29.22053  ? 152 ILE   A CA   1 
ATOM   2347 C C    . ILE   A 1 155 ? 42.93024 -10.31103 7.67869  1.000 25.70001  ? 152 ILE   A C    1 
ATOM   2348 O O    . ILE   A 1 155 ? 44.16187 -10.42729 7.63813  1.000 24.27143  ? 152 ILE   A O    1 
ATOM   2349 C CB   . ILE   A 1 155 ? 42.24530 -12.54956 6.75887  1.000 31.43869  ? 152 ILE   A CB   1 
ATOM   2350 C CG1  . ILE   A 1 155 ? 41.39764 -13.27071 5.70674  1.000 29.17386  ? 152 ILE   A CG1  1 
ATOM   2351 C CG2  . ILE   A 1 155 ? 41.90417 -13.03818 8.16155  1.000 29.41531  ? 152 ILE   A CG2  1 
ATOM   2352 C CD1  . ILE   A 1 155 ? 39.90203 -13.08157 5.87165  1.000 36.49951  ? 152 ILE   A CD1  1 
ATOM   2353 H H    . ILE   A 1 155 ? 43.14504 -10.77092 5.05473  1.000 36.02783  ? 152 ILE   A H    1 
ATOM   2354 H HA   . ILE   A 1 155 ? 41.12269 -10.82162 6.86290  1.000 34.99901  ? 152 ILE   A HA   1 
ATOM   2355 H HB   . ILE   A 1 155 ? 43.17704 -12.75116 6.57965  1.000 37.66080  ? 152 ILE   A HB   1 
ATOM   2356 H HG12 . ILE   A 1 155 ? 41.64101 -12.93488 4.82987  1.000 34.94300  ? 152 ILE   A HG12 1 
ATOM   2357 H HG13 . ILE   A 1 155 ? 41.58087 -14.22173 5.76036  1.000 34.94300  ? 152 ILE   A HG13 1 
ATOM   2358 H HG21 . ILE   A 1 155 ? 41.78257 -14.00028 8.13995  1.000 35.23274  ? 152 ILE   A HG21 1 
ATOM   2359 H HG22 . ILE   A 1 155 ? 42.63180 -12.81011 8.76107  1.000 35.23274  ? 152 ILE   A HG22 1 
ATOM   2360 H HG23 . ILE   A 1 155 ? 41.08607 -12.60789 8.45560  1.000 35.23274  ? 152 ILE   A HG23 1 
ATOM   2361 H HD11 . ILE   A 1 155 ? 39.44154 -13.59811 5.19192  1.000 43.73378  ? 152 ILE   A HD11 1 
ATOM   2362 H HD12 . ILE   A 1 155 ? 39.64033 -13.38813 6.75394  1.000 43.73378  ? 152 ILE   A HD12 1 
ATOM   2363 H HD13 . ILE   A 1 155 ? 39.68987 -12.14030 5.77212  1.000 43.73378  ? 152 ILE   A HD13 1 
ATOM   2364 N N    . LEU   A 1 156 ? 42.29820 -9.58666  8.59710  1.000 25.91524  ? 153 LEU   A N    1 
ATOM   2365 C CA   . LEU   A 1 156 ? 42.98884 -8.84549  9.64520  1.000 25.17112  ? 153 LEU   A CA   1 
ATOM   2366 C C    . LEU   A 1 156 ? 42.53131 -9.39038  10.99005 1.000 24.11543  ? 153 LEU   A C    1 
ATOM   2367 O O    . LEU   A 1 156 ? 41.33303 -9.38210  11.28923 1.000 21.98931  ? 153 LEU   A O    1 
ATOM   2368 C CB   . LEU   A 1 156 ? 42.69677 -7.34873  9.52497  1.000 26.57088  ? 153 LEU   A CB   1 
ATOM   2369 C CG   . LEU   A 1 156 ? 43.55256 -6.38044  10.34193 1.000 29.04765  ? 153 LEU   A CG   1 
ATOM   2370 C CD1  . LEU   A 1 156 ? 43.49859 -4.99845  9.71170  1.000 47.43940  ? 153 LEU   A CD1  1 
ATOM   2371 C CD2  . LEU   A 1 156 ? 43.08683 -6.32541  11.78477 1.000 40.88084  ? 153 LEU   A CD2  1 
ATOM   2372 H H    . LEU   A 1 156 ? 41.44264 -9.50742  8.63383  1.000 31.03266  ? 153 LEU   A H    1 
ATOM   2373 H HA   . LEU   A 1 156 ? 43.94801 -8.97244  9.57601  1.000 30.13971  ? 153 LEU   A HA   1 
ATOM   2374 H HB2  . LEU   A 1 156 ? 42.80858 -7.10108  8.59381  1.000 31.81943  ? 153 LEU   A HB2  1 
ATOM   2375 H HB3  . LEU   A 1 156 ? 41.77712 -7.20561  9.79820  1.000 31.81943  ? 153 LEU   A HB3  1 
ATOM   2376 H HG   . LEU   A 1 156 ? 44.47183 -6.69001  10.34541 1.000 34.79156  ? 153 LEU   A HG   1 
ATOM   2377 H HD11 . LEU   A 1 156 ? 43.97959 -4.37437  10.27742 1.000 56.86166  ? 153 LEU   A HD11 1 
ATOM   2378 H HD12 . LEU   A 1 156 ? 43.91086 -5.03510  8.83444  1.000 56.86166  ? 153 LEU   A HD12 1 
ATOM   2379 H HD13 . LEU   A 1 156 ? 42.57166 -4.72443  9.63037  1.000 56.86166  ? 153 LEU   A HD13 1 
ATOM   2380 H HD21 . LEU   A 1 156 ? 43.49672 -5.56157  12.22001 1.000 48.99138  ? 153 LEU   A HD21 1 
ATOM   2381 H HD22 . LEU   A 1 156 ? 42.12103 -6.23685  11.80170 1.000 48.99138  ? 153 LEU   A HD22 1 
ATOM   2382 H HD23 . LEU   A 1 156 ? 43.35191 -7.14345  12.23359 1.000 48.99138  ? 153 LEU   A HD23 1 
ATOM   2383 N N    . THR   A 1 157 ? 43.47792 -9.87095  11.79386 1.000 20.43985  ? 154 THR   A N    1 
ATOM   2384 C CA   . THR   A 1 157 ? 43.15878 -10.48276 13.07484 1.000 20.99514  ? 154 THR   A CA   1 
ATOM   2385 C C    . THR   A 1 157 ? 44.01385 -9.87300  14.17753 1.000 23.26030  ? 154 THR   A C    1 
ATOM   2386 O O    . THR   A 1 157 ? 45.06468 -9.27614  13.92755 1.000 21.18314  ? 154 THR   A O    1 
ATOM   2387 C CB   . THR   A 1 157 ? 43.35516 -12.00916 13.04310 1.000 22.59675  ? 154 THR   A CB   1 
ATOM   2388 O OG1  . THR   A 1 157 ? 44.66606 -12.32214 12.55835 1.000 22.07330  ? 154 THR   A OG1  1 
ATOM   2389 C CG2  . THR   A 1 157 ? 42.30821 -12.66755 12.15433 1.000 23.34953  ? 154 THR   A CG2  1 
ATOM   2390 H H    . THR   A 1 157 ? 44.31883 -9.85242  11.61457 1.000 24.46220  ? 154 THR   A H    1 
ATOM   2391 H HA   . THR   A 1 157 ? 42.22967 -10.29886 13.28420 1.000 25.12854  ? 154 THR   A HA   1 
ATOM   2392 H HB   . THR   A 1 157 ? 43.25620 -12.36396 13.94044 1.000 27.05047  ? 154 THR   A HB   1 
ATOM   2393 H HG1  . THR   A 1 157 ? 44.77375 -11.99751 11.79113 1.000 26.42233  ? 154 THR   A HG1  1 
ATOM   2394 H HG21 . THR   A 1 157 ? 42.45851 -13.62515 12.11815 1.000 27.95381  ? 154 THR   A HG21 1 
ATOM   2395 H HG22 . THR   A 1 157 ? 41.42055 -12.50138 12.50839 1.000 27.95381  ? 154 THR   A HG22 1 
ATOM   2396 H HG23 . THR   A 1 157 ? 42.36137 -12.30637 11.25565 1.000 27.95381  ? 154 THR   A HG23 1 
ATOM   2397 N N    . SER   A 1 158 ? 43.53799 -10.03264 15.41107 1.000 19.30284  ? 155 SER   A N    1 
ATOM   2398 C CA   . SER   A 1 158 ? 44.20865 -9.48834  16.58337 1.000 19.64067  ? 155 SER   A CA   1 
ATOM   2399 C C    . SER   A 1 158 ? 43.88098 -10.38058 17.77498 1.000 20.81385  ? 155 SER   A C    1 
ATOM   2400 O O    . SER   A 1 158 ? 42.98137 -11.22204 17.71669 1.000 20.60828  ? 155 SER   A O    1 
ATOM   2401 C CB   . SER   A 1 158 ? 43.79869 -8.03252  16.82538 1.000 19.28621  ? 155 SER   A CB   1 
ATOM   2402 O OG   . SER   A 1 158 ? 44.73443 -7.36988  17.65631 1.000 26.28063  ? 155 SER   A OG   1 
ATOM   2403 H H    . SER   A 1 158 ? 42.81519 -10.46038 15.59598 1.000 23.09778  ? 155 SER   A H    1 
ATOM   2404 H HA   . SER   A 1 158 ? 45.17031 -9.50348  16.45736 1.000 23.50318  ? 155 SER   A HA   1 
ATOM   2405 H HB2  . SER   A 1 158 ? 43.75403 -7.57238  15.97263 1.000 23.07783  ? 155 SER   A HB2  1 
ATOM   2406 H HB3  . SER   A 1 158 ? 42.92972 -8.01787  17.25617 1.000 23.07783  ? 155 SER   A HB3  1 
ATOM   2407 H HG   . SER   A 1 158 ? 44.75898 -7.73733  18.41128 1.000 31.47113  ? 155 SER   A HG   1 
ATOM   2408 N N    . ARG   A 1 159 ? 44.61511 -10.18179 18.86958 1.000 18.95639  ? 156 ARG   A N    1 
ATOM   2409 C CA   . ARG   A 1 159 ? 44.73331 -11.20374 19.90492 1.000 19.55625  ? 156 ARG   A CA   1 
ATOM   2410 C C    . ARG   A 1 159 ? 43.76584 -11.04686 21.07224 1.000 22.11353  ? 156 ARG   A C    1 
ATOM   2411 O O    . ARG   A 1 159 ? 43.24337 -12.05212 21.56157 1.000 23.70836  ? 156 ARG   A O    1 
ATOM   2412 C CB   . ARG   A 1 159 ? 46.16526 -11.22912 20.44568 1.000 20.18890  ? 156 ARG   A CB   1 
ATOM   2413 C CG   . ARG   A 1 159 ? 47.20942 -11.48132 19.37785 1.000 22.57392  ? 156 ARG   A CG   1 
ATOM   2414 C CD   . ARG   A 1 159 ? 48.41105 -12.21122 19.94274 1.000 21.90126  ? 156 ARG   A CD   1 
ATOM   2415 N NE   . ARG   A 1 159 ? 48.15744 -13.64079 20.07319 1.000 27.26677  ? 156 ARG   A NE   1 
ATOM   2416 C CZ   . ARG   A 1 159 ? 48.99076 -14.50325 20.63778 1.000 28.18558  ? 156 ARG   A CZ   1 
ATOM   2417 N NH1  . ARG   A 1 159 ? 50.13808 -14.11098 21.16628 1.000 35.56827  ? 156 ARG   A NH1  1 
ATOM   2418 N NH2  . ARG   A 1 159 ? 48.66388 -15.79178 20.67347 1.000 28.01618  ? 156 ARG   A NH2  1 
ATOM   2419 H H    . ARG   A 1 159 ? 45.05440 -9.46096  19.03399 1.000 22.68204  ? 156 ARG   A H    1 
ATOM   2420 H HA   . ARG   A 1 159 ? 44.53369 -12.05974 19.49465 1.000 23.40187  ? 156 ARG   A HA   1 
ATOM   2421 H HB2  . ARG   A 1 159 ? 46.36014 -10.37180 20.85545 1.000 24.16105  ? 156 ARG   A HB2  1 
ATOM   2422 H HB3  . ARG   A 1 159 ? 46.23798 -11.93639 21.10551 1.000 24.16105  ? 156 ARG   A HB3  1 
ATOM   2423 H HG2  . ARG   A 1 159 ? 46.82449 -12.02599 18.67353 1.000 27.02308  ? 156 ARG   A HG2  1 
ATOM   2424 H HG3  . ARG   A 1 159 ? 47.50989 -10.63346 19.01486 1.000 27.02308  ? 156 ARG   A HG3  1 
ATOM   2425 H HD2  . ARG   A 1 159 ? 49.16868 -12.08902 19.34947 1.000 26.21588  ? 156 ARG   A HD2  1 
ATOM   2426 H HD3  . ARG   A 1 159 ? 48.61752 -11.85690 20.82180 1.000 26.21588  ? 156 ARG   A HD3  1 
ATOM   2427 H HE   . ARG   A 1 159 ? 47.41584 -13.94571 19.76231 1.000 32.65450  ? 156 ARG   A HE   1 
ATOM   2428 H HH11 . ARG   A 1 159 ? 50.35783 -13.27972 21.14840 1.000 42.61630  ? 156 ARG   A HH11 1 
ATOM   2429 H HH12 . ARG   A 1 159 ? 50.66430 -14.68718 21.52778 1.000 42.61630  ? 156 ARG   A HH12 1 
ATOM   2430 H HH21 . ARG   A 1 159 ? 47.91980 -16.05623 20.33287 1.000 33.55378  ? 156 ARG   A HH21 1 
ATOM   2431 H HH22 . ARG   A 1 159 ? 49.19657 -16.36062 21.03715 1.000 33.55378  ? 156 ARG   A HH22 1 
ATOM   2432 N N    . GLY   A 1 160 ? 43.52100 -9.83708  21.56406 1.000 24.86050  ? 157 GLY   A N    1 
ATOM   2433 C CA   . GLY   A 1 160 ? 42.71389 -9.69453  22.75343 1.000 20.96806  ? 157 GLY   A CA   1 
ATOM   2434 C C    . GLY   A 1 160 ? 42.25538 -8.28265  23.04441 1.000 23.05075  ? 157 GLY   A C    1 
ATOM   2435 O O    . GLY   A 1 160 ? 42.50803 -7.34572  22.28085 1.000 22.62526  ? 157 GLY   A O    1 
ATOM   2436 H H    . GLY   A 1 160 ? 43.80930 -9.09995  21.22773 1.000 29.76697  ? 157 GLY   A H    1 
ATOM   2437 H HA2  . GLY   A 1 160 ? 41.92304 -10.24861 22.66151 1.000 25.09605  ? 157 GLY   A HA2  1 
ATOM   2438 H HA3  . GLY   A 1 160 ? 43.22741 -10.00132 23.51702 1.000 25.09605  ? 157 GLY   A HA3  1 
ATOM   2439 N N    . PRO   A 1 161 ? 41.55581 -8.10967  24.17081 1.000 22.65170  ? 158 PRO   A N    1 
ATOM   2440 C CA   . PRO   A 1 161 ? 41.07713 -6.76650  24.53550 1.000 24.04275  ? 158 PRO   A CA   1 
ATOM   2441 C C    . PRO   A 1 161 ? 42.18278 -5.73020  24.56687 1.000 23.67498  ? 158 PRO   A C    1 
ATOM   2442 O O    . PRO   A 1 161 ? 41.97615 -4.59411  24.12241 1.000 24.15445  ? 158 PRO   A O    1 
ATOM   2443 C CB   . PRO   A 1 161 ? 40.45796 -6.98477  25.92440 1.000 33.31810  ? 158 PRO   A CB   1 
ATOM   2444 C CG   . PRO   A 1 161 ? 40.09123 -8.43215  25.95639 1.000 28.09656  ? 158 PRO   A CG   1 
ATOM   2445 C CD   . PRO   A 1 161 ? 41.15093 -9.13023  25.15390 1.000 19.22456  ? 158 PRO   A CD   1 
ATOM   2446 H HA   . PRO   A 1 161 ? 40.38436 -6.48212  23.91899 1.000 28.78568  ? 158 PRO   A HA   1 
ATOM   2447 H HB2  . PRO   A 1 161 ? 41.10822 -6.77551  26.61308 1.000 39.91610  ? 158 PRO   A HB2  1 
ATOM   2448 H HB3  . PRO   A 1 161 ? 39.67281 -6.42474  26.02830 1.000 39.91610  ? 158 PRO   A HB3  1 
ATOM   2449 H HG2  . PRO   A 1 161 ? 40.08671 -8.75016  26.87277 1.000 33.65024  ? 158 PRO   A HG2  1 
ATOM   2450 H HG3  . PRO   A 1 161 ? 39.21639 -8.55872  25.55698 1.000 33.65024  ? 158 PRO   A HG3  1 
ATOM   2451 H HD2  . PRO   A 1 161 ? 41.89922 -9.38421  25.71645 1.000 23.00385  ? 158 PRO   A HD2  1 
ATOM   2452 H HD3  . PRO   A 1 161 ? 40.78878 -9.91305  24.71013 1.000 23.00385  ? 158 PRO   A HD3  1 
ATOM   2453 N N    . GLY   A 1 162 ? 43.35982 -6.09883  25.07410 1.000 22.49889  ? 159 GLY   A N    1 
ATOM   2454 C CA   . GLY   A 1 162 ? 44.48599 -5.18608  25.14716 1.000 21.81597  ? 159 GLY   A CA   1 
ATOM   2455 C C    . GLY   A 1 162 ? 45.08647 -4.80765  23.80916 1.000 21.09725  ? 159 GLY   A C    1 
ATOM   2456 O O    . GLY   A 1 162 ? 45.90628 -3.88393  23.76446 1.000 25.24951  ? 159 GLY   A O    1 
ATOM   2457 H H    . GLY   A 1 162 ? 43.52849 -6.88274  25.38496 1.000 26.93304  ? 159 GLY   A H    1 
ATOM   2458 H HA2  . GLY   A 1 162 ? 44.19625 -4.36931  25.58287 1.000 26.11354  ? 159 GLY   A HA2  1 
ATOM   2459 H HA3  . GLY   A 1 162 ? 45.18507 -5.59706  25.67940 1.000 26.11354  ? 159 GLY   A HA3  1 
ATOM   2460 N N    . THR   A 1 163 ? 44.71352 -5.49424  22.72916 1.000 23.37814  ? 160 THR   A N    1 
ATOM   2461 C CA   . THR   A 1 163 ? 45.16084 -5.14151  21.38880 1.000 21.54930  ? 160 THR   A CA   1 
ATOM   2462 C C    . THR   A 1 163 ? 44.08357 -4.41180  20.59548 1.000 23.39260  ? 160 THR   A C    1 
ATOM   2463 O O    . THR   A 1 163 ? 44.27804 -4.14609  19.40529 1.000 19.66808  ? 160 THR   A O    1 
ATOM   2464 C CB   . THR   A 1 163 ? 45.60660 -6.39326  20.62170 1.000 22.82165  ? 160 THR   A CB   1 
ATOM   2465 O OG1  . THR   A 1 163 ? 44.48213 -7.24736  20.37890 1.000 19.30597  ? 160 THR   A OG1  1 
ATOM   2466 C CG2  . THR   A 1 163 ? 46.66320 -7.16502  21.40299 1.000 26.70484  ? 160 THR   A CG2  1 
ATOM   2467 H H    . THR   A 1 163 ? 44.19340 -6.17877  22.75121 1.000 27.98814  ? 160 THR   A H    1 
ATOM   2468 H HA   . THR   A 1 163 ? 45.93055 -4.55676  21.46950 1.000 25.79354  ? 160 THR   A HA   1 
ATOM   2469 H HB   . THR   A 1 163 ? 45.99252 -6.12020  19.77470 1.000 27.32035  ? 160 THR   A HB   1 
ATOM   2470 H HG1  . THR   A 1 163 ? 43.93138 -6.86118  19.87577 1.000 23.10153  ? 160 THR   A HG1  1 
ATOM   2471 H HG21 . THR   A 1 163 ? 46.92082 -7.96227  20.91419 1.000 31.98018  ? 160 THR   A HG21 1 
ATOM   2472 H HG22 . THR   A 1 163 ? 47.44776 -6.61053  21.53681 1.000 31.98018  ? 160 THR   A HG22 1 
ATOM   2473 H HG23 . THR   A 1 163 ? 46.31107 -7.42629  22.26823 1.000 31.98018  ? 160 THR   A HG23 1 
ATOM   2474 N N    . SER   A 1 164 ? 42.96016 -4.07120  21.23538 1.000 18.26267  ? 161 SER   A N    1 
ATOM   2475 C CA   . SER   A 1 164 ? 41.82040 -3.52124  20.50827 1.000 18.47263  ? 161 SER   A CA   1 
ATOM   2476 C C    . SER   A 1 164 ? 42.16511 -2.20052  19.83068 1.000 20.25079  ? 161 SER   A C    1 
ATOM   2477 O O    . SER   A 1 164 ? 41.71037 -1.93615  18.71203 1.000 21.04965  ? 161 SER   A O    1 
ATOM   2478 C CB   . SER   A 1 164 ? 40.63506 -3.33894  21.45743 1.000 20.66128  ? 161 SER   A CB   1 
ATOM   2479 O OG   . SER   A 1 164 ? 40.13190 -4.58979  21.89363 1.000 23.52135  ? 161 SER   A OG   1 
ATOM   2480 H H    . SER   A 1 164 ? 42.83578 -4.14883  22.08279 1.000 21.84957  ? 161 SER   A H    1 
ATOM   2481 H HA   . SER   A 1 164 ? 41.56589 -4.15099  19.81578 1.000 22.10153  ? 161 SER   A HA   1 
ATOM   2482 H HB2  . SER   A 1 164 ? 40.92640 -2.83034  22.23031 1.000 24.72790  ? 161 SER   A HB2  1 
ATOM   2483 H HB3  . SER   A 1 164 ? 39.93038 -2.86137  20.99242 1.000 24.72790  ? 161 SER   A HB3  1 
ATOM   2484 H HG   . SER   A 1 164 ? 39.46488 -4.47358  22.39081 1.000 28.15999  ? 161 SER   A HG   1 
ATOM   2485 N N    . PHE   A 1 165 ? 42.95694 -1.35217  20.49116 1.000 19.01910  ? 162 PHE   A N    1 
ATOM   2486 C CA   . PHE   A 1 165 ? 43.32038 -0.07053  19.89136 1.000 18.34935  ? 162 PHE   A CA   1 
ATOM   2487 C C    . PHE   A 1 165 ? 44.16372 -0.27230  18.63788 1.000 19.39901  ? 162 PHE   A C    1 
ATOM   2488 O O    . PHE   A 1 165 ? 43.90718 0.34188   17.59602 1.000 21.24367  ? 162 PHE   A O    1 
ATOM   2489 C CB   . PHE   A 1 165 ? 44.06905 0.79813   20.90409 1.000 24.22348  ? 162 PHE   A CB   1 
ATOM   2490 C CG   . PHE   A 1 165 ? 43.17615 1.47039   21.91020 1.000 25.89783  ? 162 PHE   A CG   1 
ATOM   2491 C CD1  . PHE   A 1 165 ? 42.39204 2.55236   21.54619 1.000 23.04938  ? 162 PHE   A CD1  1 
ATOM   2492 C CD2  . PHE   A 1 165 ? 43.13484 1.03308   23.22268 1.000 26.07277  ? 162 PHE   A CD2  1 
ATOM   2493 C CE1  . PHE   A 1 165 ? 41.57528 3.17680   22.46813 1.000 29.02478  ? 162 PHE   A CE1  1 
ATOM   2494 C CE2  . PHE   A 1 165 ? 42.31922 1.65625   24.15140 1.000 25.58822  ? 162 PHE   A CE2  1 
ATOM   2495 C CZ   . PHE   A 1 165 ? 41.53898 2.72832   23.77284 1.000 31.82363  ? 162 PHE   A CZ   1 
ATOM   2496 H H    . PHE   A 1 165 ? 43.28960 -1.49281  21.27165 1.000 22.75729  ? 162 PHE   A H    1 
ATOM   2497 H HA   . PHE   A 1 165 ? 42.50637 0.39403   19.64142 1.000 21.95360  ? 162 PHE   A HA   1 
ATOM   2498 H HB2  . PHE   A 1 165 ? 44.69431 0.23908   21.39134 1.000 29.00255  ? 162 PHE   A HB2  1 
ATOM   2499 H HB3  . PHE   A 1 165 ? 44.54832 1.49193   20.42465 1.000 29.00255  ? 162 PHE   A HB3  1 
ATOM   2500 H HD1  . PHE   A 1 165 ? 42.41585 2.86234   20.66969 1.000 27.59363  ? 162 PHE   A HD1  1 
ATOM   2501 H HD2  . PHE   A 1 165 ? 43.66119 0.31215   23.48367 1.000 31.22169  ? 162 PHE   A HD2  1 
ATOM   2502 H HE1  . PHE   A 1 165 ? 41.04983 3.89937   22.20990 1.000 34.76410  ? 162 PHE   A HE1  1 
ATOM   2503 H HE2  . PHE   A 1 165 ? 42.29748 1.35211   25.03000 1.000 30.64023  ? 162 PHE   A HE2  1 
ATOM   2504 H HZ   . PHE   A 1 165 ? 40.98977 3.14802   24.39503 1.000 38.12272  ? 162 PHE   A HZ   1 
ATOM   2505 N N    . GLU   A 1 166 ? 45.18917 -1.12197  18.72558 1.000 18.93979  ? 163 GLU   A N    1 
ATOM   2506 C CA   . GLU   A 1 166 ? 46.00634 -1.41355  17.55247 1.000 23.27351  ? 163 GLU   A CA   1 
ATOM   2507 C C    . GLU   A 1 166 ? 45.16862 -2.07796  16.46927 1.000 22.73649  ? 163 GLU   A C    1 
ATOM   2508 O O    . GLU   A 1 166 ? 45.31879 -1.78038  15.27783 1.000 20.53957  ? 163 GLU   A O    1 
ATOM   2509 C CB   . GLU   A 1 166 ? 47.18373 -2.30314  17.95151 1.000 21.85577  ? 163 GLU   A CB   1 
ATOM   2510 C CG   . GLU   A 1 166 ? 48.06253 -1.70638  19.03992 1.000 27.55933  ? 163 GLU   A CG   1 
ATOM   2511 C CD   . GLU   A 1 166 ? 48.60983 -2.75747  19.98483 1.000 47.99189  ? 163 GLU   A CD   1 
ATOM   2512 O OE1  . GLU   A 1 166 ? 49.55851 -3.47470  19.60162 1.000 34.60063  ? 163 GLU   A OE1  1 
ATOM   2513 O OE2  . GLU   A 1 166 ? 48.07854 -2.87328  21.10917 1.000 40.91858  ? 163 GLU   A OE2  1 
ATOM   2514 H H    . GLU   A 1 166 ? 45.42758 -1.53513  19.44116 1.000 22.66213  ? 163 GLU   A H    1 
ATOM   2515 H HA   . GLU   A 1 166 ? 46.36599 -0.58728  17.19355 1.000 27.86258  ? 163 GLU   A HA   1 
ATOM   2516 H HB2  . GLU   A 1 166 ? 46.83863 -3.14811  18.27986 1.000 26.16130  ? 163 GLU   A HB2  1 
ATOM   2517 H HB3  . GLU   A 1 166 ? 47.73985 -2.45274  17.17096 1.000 26.16130  ? 163 GLU   A HB3  1 
ATOM   2518 H HG2  . GLU   A 1 166 ? 48.81372 -1.25204  18.62738 1.000 33.00557  ? 163 GLU   A HG2  1 
ATOM   2519 H HG3  . GLU   A 1 166 ? 47.53925 -1.07692  19.56037 1.000 33.00557  ? 163 GLU   A HG3  1 
ATOM   2520 N N    . PHE   A 1 167 ? 44.27089 -2.97500  16.87454 1.000 19.30171  ? 164 PHE   A N    1 
ATOM   2521 C CA   . PHE   A 1 167 ? 43.34319 -3.60152  15.94020 1.000 19.92826  ? 164 PHE   A CA   1 
ATOM   2522 C C    . PHE   A 1 167 ? 42.51717 -2.55228  15.20624 1.000 31.45946  ? 164 PHE   A C    1 
ATOM   2523 O O    . PHE   A 1 167 ? 42.41607 -2.57342  13.97393 1.000 20.22847  ? 164 PHE   A O    1 
ATOM   2524 C CB   . PHE   A 1 167 ? 42.45652 -4.57530  16.71993 1.000 19.70700  ? 164 PHE   A CB   1 
ATOM   2525 C CG   . PHE   A 1 167 ? 41.37730 -5.22254  15.90888 1.000 20.24668  ? 164 PHE   A CG   1 
ATOM   2526 C CD1  . PHE   A 1 167 ? 41.68534 -6.11985  14.90215 1.000 21.43951  ? 164 PHE   A CD1  1 
ATOM   2527 C CD2  . PHE   A 1 167 ? 40.04571 -4.96849  16.19053 1.000 21.44903  ? 164 PHE   A CD2  1 
ATOM   2528 C CE1  . PHE   A 1 167 ? 40.68481 -6.72821  14.17126 1.000 22.10327  ? 164 PHE   A CE1  1 
ATOM   2529 C CE2  . PHE   A 1 167 ? 39.04322 -5.57303  15.46562 1.000 21.55301  ? 164 PHE   A CE2  1 
ATOM   2530 C CZ   . PHE   A 1 167 ? 39.36202 -6.45683  14.45529 1.000 24.39924  ? 164 PHE   A CZ   1 
ATOM   2531 H H    . PHE   A 1 167 ? 44.17864 -3.23854  17.68795 1.000 23.09643  ? 164 PHE   A H    1 
ATOM   2532 H HA   . PHE   A 1 167 ? 43.82954 -4.10087  15.26565 1.000 23.84828  ? 164 PHE   A HA   1 
ATOM   2533 H HB2  . PHE   A 1 167 ? 43.01577 -5.28176  17.07917 1.000 23.58277  ? 164 PHE   A HB2  1 
ATOM   2534 H HB3  . PHE   A 1 167 ? 42.02819 -4.09111  17.44311 1.000 23.58277  ? 164 PHE   A HB3  1 
ATOM   2535 H HD1  . PHE   A 1 167 ? 42.57532 -6.31516  14.71593 1.000 25.66179  ? 164 PHE   A HD1  1 
ATOM   2536 H HD2  . PHE   A 1 167 ? 39.82560 -4.38213  16.87800 1.000 25.67321  ? 164 PHE   A HD2  1 
ATOM   2537 H HE1  . PHE   A 1 167 ? 40.90206 -7.32050  13.48796 1.000 26.45830  ? 164 PHE   A HE1  1 
ATOM   2538 H HE2  . PHE   A 1 167 ? 38.15253 -5.38588  15.65677 1.000 25.79798  ? 164 PHE   A HE2  1 
ATOM   2539 H HZ   . PHE   A 1 167 ? 38.68660 -6.86894  13.96655 1.000 29.21346  ? 164 PHE   A HZ   1 
ATOM   2540 N N    . ALA   A 1 168 ? 41.94057 -1.60451  15.94889 1.000 20.23923  ? 165 ALA   A N    1 
ATOM   2541 C CA   . ALA   A 1 168 ? 41.08370 -0.59800  15.33026 1.000 20.05374  ? 165 ALA   A CA   1 
ATOM   2542 C C    . ALA   A 1 168 ? 41.87805 0.33233   14.42103 1.000 21.34945  ? 165 ALA   A C    1 
ATOM   2543 O O    . ALA   A 1 168 ? 41.43401 0.65032   13.31125 1.000 20.70599  ? 165 ALA   A O    1 
ATOM   2544 C CB   . ALA   A 1 168 ? 40.35773 0.20208   16.41067 1.000 18.89953  ? 165 ALA   A CB   1 
ATOM   2545 H H    . ALA   A 1 168 ? 42.02903 -1.52452  16.80058 1.000 24.22145  ? 165 ALA   A H    1 
ATOM   2546 H HA   . ALA   A 1 168 ? 40.41920 -1.04882  14.78611 1.000 23.99887  ? 165 ALA   A HA   1 
ATOM   2547 H HB1  . ALA   A 1 168 ? 39.77977 0.85485   15.98552 1.000 22.61381  ? 165 ALA   A HB1  1 
ATOM   2548 H HB2  . ALA   A 1 168 ? 39.82909 -0.40513  16.95171 1.000 22.61381  ? 165 ALA   A HB2  1 
ATOM   2549 H HB3  . ALA   A 1 168 ? 41.01419 0.65263   16.96471 1.000 22.61381  ? 165 ALA   A HB3  1 
ATOM   2550 N N    . LEU   A 1 169 ? 43.05207 0.78313   14.87125 1.000 18.43139  ? 166 LEU   A N    1 
ATOM   2551 C CA   . LEU   A 1 169 ? 43.85491 1.68282   14.04926 1.000 23.21794  ? 166 LEU   A CA   1 
ATOM   2552 C C    . LEU   A 1 169 ? 44.35497 0.99420   12.78598 1.000 23.73250  ? 166 LEU   A C    1 
ATOM   2553 O O    . LEU   A 1 169 ? 44.55525 1.65695   11.76171 1.000 19.49044  ? 166 LEU   A O    1 
ATOM   2554 C CB   . LEU   A 1 169 ? 45.02921 2.23005   14.86106 1.000 19.49025  ? 166 LEU   A CB   1 
ATOM   2555 C CG   . LEU   A 1 169 ? 44.66462 3.26859   15.92606 1.000 22.54209  ? 166 LEU   A CG   1 
ATOM   2556 C CD1  . LEU   A 1 169 ? 45.87167 3.62272   16.78205 1.000 28.29189  ? 166 LEU   A CD1  1 
ATOM   2557 C CD2  . LEU   A 1 169 ? 44.08481 4.51819   15.27678 1.000 27.43466  ? 166 LEU   A CD2  1 
ATOM   2558 H H    . LEU   A 1 169 ? 43.39759 0.58604   15.63373 1.000 22.05204  ? 166 LEU   A H    1 
ATOM   2559 H HA   . LEU   A 1 169 ? 43.30374 2.43426   13.78010 1.000 27.79590  ? 166 LEU   A HA   1 
ATOM   2560 H HB2  . LEU   A 1 169 ? 45.45800 1.48778   15.31501 1.000 23.32267  ? 166 LEU   A HB2  1 
ATOM   2561 H HB3  . LEU   A 1 169 ? 45.65356 2.64983   14.24879 1.000 23.32267  ? 166 LEU   A HB3  1 
ATOM   2562 H HG   . LEU   A 1 169 ? 43.99038 2.88836   16.51064 1.000 26.98488  ? 166 LEU   A HG   1 
ATOM   2563 H HD11 . LEU   A 1 169 ? 45.60600 4.27652   17.44754 1.000 33.88464  ? 166 LEU   A HD11 1 
ATOM   2564 H HD12 . LEU   A 1 169 ? 46.19590 2.81944   17.21853 1.000 33.88464  ? 166 LEU   A HD12 1 
ATOM   2565 H HD13 . LEU   A 1 169 ? 46.56469 3.99272   16.21309 1.000 33.88464  ? 166 LEU   A HD13 1 
ATOM   2566 H HD21 . LEU   A 1 169 ? 44.09403 5.24252   15.92188 1.000 32.85596  ? 166 LEU   A HD21 1 
ATOM   2567 H HD22 . LEU   A 1 169 ? 44.62570 4.75400   14.50689 1.000 32.85596  ? 166 LEU   A HD22 1 
ATOM   2568 H HD23 . LEU   A 1 169 ? 43.17400 4.33541   14.99766 1.000 32.85596  ? 166 LEU   A HD23 1 
ATOM   2569 N N    . ALA   A 1 170 ? 44.56201 -0.32436  12.83474 1.000 19.67387  ? 167 ALA   A N    1 
ATOM   2570 C CA   . ALA   A 1 170 ? 44.93064 -1.05463  11.62658 1.000 24.56923  ? 167 ALA   A CA   1 
ATOM   2571 C C    . ALA   A 1 170 ? 43.79838 -1.02998  10.60828 1.000 24.93979  ? 167 ALA   A C    1 
ATOM   2572 O O    . ALA   A 1 170 ? 44.04263 -0.91208  9.40217  1.000 24.73036  ? 167 ALA   A O    1 
ATOM   2573 C CB   . ALA   A 1 170 ? 45.30629 -2.49455  11.97430 1.000 27.52267  ? 167 ALA   A CB   1 
ATOM   2574 H H    . ALA   A 1 170 ? 44.49624 -0.80867  13.54235 1.000 23.54302  ? 167 ALA   A H    1 
ATOM   2575 H HA   . ALA   A 1 170 ? 45.70784 -0.63152  11.22929 1.000 29.41745  ? 167 ALA   A HA   1 
ATOM   2576 H HB1  . ALA   A 1 170 ? 45.57057 -2.95659  11.16340 1.000 32.96158  ? 167 ALA   A HB1  1 
ATOM   2577 H HB2  . ALA   A 1 170 ? 46.04334 -2.48516  12.60484 1.000 32.96158  ? 167 ALA   A HB2  1 
ATOM   2578 H HB3  . ALA   A 1 170 ? 44.53785 -2.93456  12.37025 1.000 32.96158  ? 167 ALA   A HB3  1 
ATOM   2579 N N    . ILE   A 1 171 ? 42.55319 -1.14685  11.07512 1.000 23.91197  ? 168 ILE   A N    1 
ATOM   2580 C CA   . ILE   A 1 171 ? 41.40746 -1.02942  10.17761 1.000 23.06938  ? 168 ILE   A CA   1 
ATOM   2581 C C    . ILE   A 1 171 ? 41.38475 0.35280   9.53751  1.000 28.87869  ? 168 ILE   A C    1 
ATOM   2582 O O    . ILE   A 1 171 ? 41.19304 0.49375   8.32387  1.000 24.28959  ? 168 ILE   A O    1 
ATOM   2583 C CB   . ILE   A 1 171 ? 40.09885 -1.31925  10.93598 1.000 26.07024  ? 168 ILE   A CB   1 
ATOM   2584 C CG1  . ILE   A 1 171 ? 40.08878 -2.75975  11.45537 1.000 23.80167  ? 168 ILE   A CG1  1 
ATOM   2585 C CG2  . ILE   A 1 171 ? 38.89380 -1.05428  10.03694 1.000 26.06759  ? 168 ILE   A CG2  1 
ATOM   2586 C CD1  . ILE   A 1 171 ? 38.94227 -3.06264  12.40108 1.000 22.82891  ? 168 ILE   A CD1  1 
ATOM   2587 H H    . ILE   A 1 171 ? 42.34862 -1.29248  11.89764 1.000 28.62874  ? 168 ILE   A H    1 
ATOM   2588 H HA   . ILE   A 1 171 ? 41.49680 -1.68897  9.47198  1.000 27.61763  ? 168 ILE   A HA   1 
ATOM   2589 H HB   . ILE   A 1 171 ? 40.04656 -0.72311  11.69938 1.000 31.21866  ? 168 ILE   A HB   1 
ATOM   2590 H HG12 . ILE   A 1 171 ? 40.01566 -3.36301  10.69931 1.000 28.49638  ? 168 ILE   A HG12 1 
ATOM   2591 H HG13 . ILE   A 1 171 ? 40.91706 -2.92467  11.93250 1.000 28.49638  ? 168 ILE   A HG13 1 
ATOM   2592 H HG21 . ILE   A 1 171 ? 38.10070 -1.42529  10.45438 1.000 31.21548  ? 168 ILE   A HG21 1 
ATOM   2593 H HG22 . ILE   A 1 171 ? 38.78995 -0.09672  9.92209  1.000 31.21548  ? 168 ILE   A HG22 1 
ATOM   2594 H HG23 . ILE   A 1 171 ? 39.04289 -1.47640  9.17642  1.000 31.21548  ? 168 ILE   A HG23 1 
ATOM   2595 H HD11 . ILE   A 1 171 ? 39.10185 -3.91960  12.82657 1.000 27.32907  ? 168 ILE   A HD11 1 
ATOM   2596 H HD12 . ILE   A 1 171 ? 38.89356 -2.36405  13.07227 1.000 27.32907  ? 168 ILE   A HD12 1 
ATOM   2597 H HD13 . ILE   A 1 171 ? 38.11526 -3.09346  11.89510 1.000 27.32907  ? 168 ILE   A HD13 1 
ATOM   2598 N N    . VAL   A 1 172 ? 41.58410 1.39503   10.34824 1.000 26.36798  ? 169 VAL   A N    1 
ATOM   2599 C CA   . VAL   A 1 172 ? 41.57719 2.75827   9.82536  1.000 26.57314  ? 169 VAL   A CA   1 
ATOM   2600 C C    . VAL   A 1 172 ? 42.66862 2.93052   8.77749  1.000 29.82921  ? 169 VAL   A C    1 
ATOM   2601 O O    . VAL   A 1 172 ? 42.44118 3.51413   7.71080  1.000 28.92314  ? 169 VAL   A O    1 
ATOM   2602 C CB   . VAL   A 1 172 ? 41.73310 3.76789   10.97823 1.000 27.89220  ? 169 VAL   A CB   1 
ATOM   2603 C CG1  . VAL   A 1 172 ? 41.90406 5.18253   10.43649 1.000 25.75901  ? 169 VAL   A CG1  1 
ATOM   2604 C CG2  . VAL   A 1 172 ? 40.53602 3.68771   11.91799 1.000 22.16828  ? 169 VAL   A CG2  1 
ATOM   2605 H H    . VAL   A 1 172 ? 41.72388 1.33890   11.19495 1.000 31.57595  ? 169 VAL   A H    1 
ATOM   2606 H HA   . VAL   A 1 172 ? 40.72334 2.92162   9.39507  1.000 31.82214  ? 169 VAL   A HA   1 
ATOM   2607 H HB   . VAL   A 1 172 ? 42.53031 3.54634   11.48446 1.000 33.40501  ? 169 VAL   A HB   1 
ATOM   2608 H HG11 . VAL   A 1 172 ? 41.75267 5.81631   11.15504 1.000 30.84518  ? 169 VAL   A HG11 1 
ATOM   2609 H HG12 . VAL   A 1 172 ? 42.80538 5.28203   10.09209 1.000 30.84518  ? 169 VAL   A HG12 1 
ATOM   2610 H HG13 . VAL   A 1 172 ? 41.26036 5.32842   9.72566  1.000 30.84518  ? 169 VAL   A HG13 1 
ATOM   2611 H HG21 . VAL   A 1 172 ? 40.66616 4.31173   12.64913 1.000 26.53631  ? 169 VAL   A HG21 1 
ATOM   2612 H HG22 . VAL   A 1 172 ? 39.73232 3.91763   11.42596 1.000 26.53631  ? 169 VAL   A HG22 1 
ATOM   2613 H HG23 . VAL   A 1 172 ? 40.46543 2.78392   12.26308 1.000 26.53631  ? 169 VAL   A HG23 1 
ATOM   2614 N N    . GLU   A 1 173 ? 43.86912 2.42295   9.06147  1.000 23.65308  ? 170 GLU   A N    1 
ATOM   2615 C CA   . GLU   A 1 173 ? 44.96740 2.54712   8.10954  1.000 32.27812  ? 170 GLU   A CA   1 
ATOM   2616 C C    . GLU   A 1 173 ? 44.64396 1.83726   6.80097  1.000 30.82350  ? 170 GLU   A C    1 
ATOM   2617 O O    . GLU   A 1 173 ? 44.96379 2.33998   5.71777  1.000 30.30659  ? 170 GLU   A O    1 
ATOM   2618 C CB   . GLU   A 1 173 ? 46.25107 1.98971   8.72520  1.000 33.84101  ? 170 GLU   A CB   1 
ATOM   2619 C CG   . GLU   A 1 173 ? 47.48622 2.15080   7.85437  1.000 46.92214  ? 170 GLU   A CG   1 
ATOM   2620 C CD   . GLU   A 1 173 ? 48.76213 1.76062   8.57606  1.000 54.64974  ? 170 GLU   A CD   1 
ATOM   2621 O OE1  . GLU   A 1 173 ? 48.77354 1.79563   9.82467  1.000 61.84254  ? 170 GLU   A OE1  1 
ATOM   2622 O OE2  . GLU   A 1 173 ? 49.75137 1.41557   7.89561  1.000 68.08382  ? 170 GLU   A OE2  1 
ATOM   2623 H H    . GLU   A 1 173 ? 44.06957 2.00845   9.78784  1.000 28.31807  ? 170 GLU   A H    1 
ATOM   2624 H HA   . GLU   A 1 173 ? 45.11108 3.48570   7.91123  1.000 38.66811  ? 170 GLU   A HA   1 
ATOM   2625 H HB2  . GLU   A 1 173 ? 46.41920 2.45190   9.56128  1.000 40.54358  ? 170 GLU   A HB2  1 
ATOM   2626 H HB3  . GLU   A 1 173 ? 46.12917 1.04145   8.88902  1.000 40.54358  ? 170 GLU   A HB3  1 
ATOM   2627 H HG2  . GLU   A 1 173 ? 47.39815 1.58454   7.07175  1.000 56.24094  ? 170 GLU   A HG2  1 
ATOM   2628 H HG3  . GLU   A 1 173 ? 47.56500 3.07928   7.58489  1.000 56.24094  ? 170 GLU   A HG3  1 
ATOM   2629 N N    . ALA   A 1 174 ? 44.00240 0.66976   6.88004  1.000 25.47591  ? 171 ALA   A N    1 
ATOM   2630 C CA   . ALA   A 1 174 ? 43.65562 -0.06647  5.66965  1.000 27.36888  ? 171 ALA   A CA   1 
ATOM   2631 C C    . ALA   A 1 174 ? 42.61523 0.67950   4.84246  1.000 30.55083  ? 171 ALA   A C    1 
ATOM   2632 O O    . ALA   A 1 174 ? 42.66987 0.66498   3.60729  1.000 32.67623  ? 171 ALA   A O    1 
ATOM   2633 C CB   . ALA   A 1 174 ? 43.14417 -1.45966  6.03616  1.000 26.18420  ? 171 ALA   A CB   1 
ATOM   2634 H H    A ALA   A 1 174 ? 43.76081 0.28908   7.61237  0.530 30.50547  ? 171 ALA   A H    1 
ATOM   2635 H H    B ALA   A 1 174 ? 43.76081 0.28908   7.61237  0.470 30.50547  ? 171 ALA   A H    1 
ATOM   2636 H HA   . ALA   A 1 174 ? 44.45388 -0.16673  5.12778  1.000 32.77703  ? 171 ALA   A HA   1 
ATOM   2637 H HB1  . ALA   A 1 174 ? 42.90817 -1.93339  5.22327  1.000 31.35541  ? 171 ALA   A HB1  1 
ATOM   2638 H HB2  . ALA   A 1 174 ? 43.84363 -1.93905  6.50717  1.000 31.35541  ? 171 ALA   A HB2  1 
ATOM   2639 H HB3  . ALA   A 1 174 ? 42.36374 -1.36998  6.60519  1.000 31.35541  ? 171 ALA   A HB3  1 
ATOM   2640 N N    . LEU   A 1 175 ? 41.66106 1.33495   5.50304  1.000 28.79771  ? 172 LEU   A N    1 
ATOM   2641 C CA   . LEU   A 1 175 ? 40.55957 1.99966   4.81839  1.000 28.72310  ? 172 LEU   A CA   1 
ATOM   2642 C C    . LEU   A 1 175 ? 40.90494 3.42832   4.40930  1.000 33.38735  ? 172 LEU   A C    1 
ATOM   2643 O O    . LEU   A 1 175 ? 40.70431 3.80713   3.25123  1.000 31.48928  ? 172 LEU   A O    1 
ATOM   2644 C CB   . LEU   A 1 175 ? 39.31632 2.00071   5.71447  1.000 29.89166  ? 172 LEU   A CB   1 
ATOM   2645 C CG   . LEU   A 1 175 ? 38.29762 0.88194   5.49097  1.000 33.01922  ? 172 LEU   A CG   1 
ATOM   2646 C CD1  . LEU   A 1 175 ? 38.98974 -0.45519  5.30955  1.000 34.55612  ? 172 LEU   A CD1  1 
ATOM   2647 C CD2  . LEU   A 1 175 ? 37.31452 0.82041   6.65219  1.000 34.19985  ? 172 LEU   A CD2  1 
ATOM   2648 H H    . LEU   A 1 175 ? 41.63103 1.40866   6.35935  1.000 34.49162  ? 172 LEU   A H    1 
ATOM   2649 H HA   . LEU   A 1 175 ? 40.35802 1.50187   4.01062  1.000 34.40209  ? 172 LEU   A HA   1 
ATOM   2650 H HB2  . LEU   A 1 175 ? 39.61248 1.93357   6.63571  1.000 35.80436  ? 172 LEU   A HB2  1 
ATOM   2651 H HB3  . LEU   A 1 175 ? 38.84967 2.83979   5.57632  1.000 35.80436  ? 172 LEU   A HB3  1 
ATOM   2652 H HG   . LEU   A 1 175 ? 37.80108 1.07005   4.67920  1.000 39.55744  ? 172 LEU   A HG   1 
ATOM   2653 H HD11 . LEU   A 1 175 ? 38.34111 -1.16582  5.43277  1.000 41.40172  ? 172 LEU   A HD11 1 
ATOM   2654 H HD12 . LEU   A 1 175 ? 39.36255 -0.49904  4.41513  1.000 41.40172  ? 172 LEU   A HD12 1 
ATOM   2655 H HD13 . LEU   A 1 175 ? 39.69795 -0.53604  5.96743  1.000 41.40172  ? 172 LEU   A HD13 1 
ATOM   2656 H HD21 . LEU   A 1 175 ? 36.64093 0.14928   6.46048  1.000 40.97419  ? 172 LEU   A HD21 1 
ATOM   2657 H HD22 . LEU   A 1 175 ? 37.79543 0.58479   7.46096  1.000 40.97419  ? 172 LEU   A HD22 1 
ATOM   2658 H HD23 . LEU   A 1 175 ? 36.89555 1.68889   6.75762  1.000 40.97419  ? 172 LEU   A HD23 1 
ATOM   2659 N N    . ASN   A 1 176 ? 41.42458 4.23009   5.34178  1.000 34.16039  ? 173 ASN   A N    1 
ATOM   2660 C CA   . ASN   A 1 176 ? 41.62678 5.65320   5.11027  1.000 31.27806  ? 173 ASN   A CA   1 
ATOM   2661 C C    . ASN   A 1 176 ? 43.08729 6.06249   4.98579  1.000 31.88857  ? 173 ASN   A C    1 
ATOM   2662 O O    . ASN   A 1 176 ? 43.35670 7.23281   4.69345  1.000 39.46303  ? 173 ASN   A O    1 
ATOM   2663 C CB   . ASN   A 1 176 ? 40.97934 6.46861   6.23976  1.000 34.71380  ? 173 ASN   A CB   1 
ATOM   2664 C CG   . ASN   A 1 176 ? 39.49599 6.19310   6.38087  1.000 40.69622  ? 173 ASN   A CG   1 
ATOM   2665 O OD1  . ASN   A 1 176 ? 38.99393 5.98400   7.48447  1.000 62.52791  ? 173 ASN   A OD1  1 
ATOM   2666 N ND2  . ASN   A 1 176 ? 38.78663 6.18680   5.26003  1.000 44.53981  ? 173 ASN   A ND2  1 
ATOM   2667 H H    . ASN   A 1 176 ? 41.66895 3.96638   6.12302  1.000 40.92684  ? 173 ASN   A H    1 
ATOM   2668 H HA   . ASN   A 1 176 ? 41.19020 5.88549   4.27580  1.000 37.46805  ? 173 ASN   A HA   1 
ATOM   2669 H HB2  . ASN   A 1 176 ? 41.40832 6.24219   7.07977  1.000 41.59094  ? 173 ASN   A HB2  1 
ATOM   2670 H HB3  . ASN   A 1 176 ? 41.09308 7.41370   6.05333  1.000 41.59094  ? 173 ASN   A HB3  1 
ATOM   2671 H HD21 . ASN   A 1 176 ? 37.94053 6.03525   5.28748  1.000 53.38214  ? 173 ASN   A HD21 1 
ATOM   2672 H HD22 . ASN   A 1 176 ? 39.17282 6.33427   4.50590  1.000 53.38214  ? 173 ASN   A HD22 1 
ATOM   2673 N N    . GLY   A 1 177 ? 44.02911 5.15317   5.20357  1.000 27.41355  ? 174 GLY   A N    1 
ATOM   2674 C CA   . GLY   A 1 177 ? 45.43265 5.44396   5.00362  1.000 31.01980  ? 174 GLY   A CA   1 
ATOM   2675 C C    . GLY   A 1 177 ? 46.16096 5.74910   6.30237  1.000 34.32562  ? 174 GLY   A C    1 
ATOM   2676 O O    . GLY   A 1 177 ? 45.57017 5.92803   7.37021  1.000 30.29532  ? 174 GLY   A O    1 
ATOM   2677 H H    . GLY   A 1 177 ? 43.87308 4.35089   5.47116  1.000 32.83064  ? 174 GLY   A H    1 
ATOM   2678 H HA2  . GLY   A 1 177 ? 45.86117 4.67993   4.58706  1.000 37.15813  ? 174 GLY   A HA2  1 
ATOM   2679 H HA3  . GLY   A 1 177 ? 45.51960 6.21269   4.41848  1.000 37.15813  ? 174 GLY   A HA3  1 
ATOM   2680 N N    . LYS   A 1 178 ? 47.48818 5.82913   6.17941  1.000 31.05432  ? 175 LYS   A N    1 
ATOM   2681 C CA   . LYS   A 1 178 ? 48.35184 5.93521   7.35085  1.000 41.19367  ? 175 LYS   A CA   1 
ATOM   2682 C C    . LYS   A 1 178 ? 48.28184 7.31452   7.99583  1.000 43.88080  ? 175 LYS   A C    1 
ATOM   2683 O O    . LYS   A 1 178 ? 48.45392 7.43325   9.21501  1.000 34.63149  ? 175 LYS   A O    1 
ATOM   2684 C CB   . LYS   A 1 178 ? 49.78949 5.59731   6.94726  1.000 45.06609  ? 175 LYS   A CB   1 
ATOM   2685 C CG   . LYS   A 1 178 ? 50.82508 5.70466   8.05787  1.000 95.57702  ? 175 LYS   A CG   1 
ATOM   2686 C CD   . LYS   A 1 178 ? 51.57104 7.03298   8.01150  1.000 136.96283 ? 175 LYS   A CD   1 
ATOM   2687 C CE   . LYS   A 1 178 ? 52.92698 6.93682   8.69717  1.000 121.58310 ? 175 LYS   A CE   1 
ATOM   2688 N NZ   . LYS   A 1 178 ? 53.88960 6.10374   7.91983  1.000 125.72865 ? 175 LYS   A NZ   1 
ATOM   2689 H H    . LYS   A 1 178 ? 47.91074 5.82398   5.43040  1.000 37.19955  ? 175 LYS   A H    1 
ATOM   2690 H HA   . LYS   A 1 178 ? 48.06036 5.29560   8.01931  1.000 49.36678  ? 175 LYS   A HA   1 
ATOM   2691 H HB2  . LYS   A 1 178 ? 49.80825 4.68346   6.62256  1.000 54.01368  ? 175 LYS   A HB2  1 
ATOM   2692 H HB3  . LYS   A 1 178 ? 50.05908 6.20574   6.24154  1.000 54.01368  ? 175 LYS   A HB3  1 
ATOM   2693 H HG2  . LYS   A 1 178 ? 50.38075 5.63610   8.91739  1.000 114.62679 ? 175 LYS   A HG2  1 
ATOM   2694 H HG3  . LYS   A 1 178 ? 51.47305 4.98931   7.96137  1.000 114.62679 ? 175 LYS   A HG3  1 
ATOM   2695 H HD2  . LYS   A 1 178 ? 51.71463 7.28857   7.08686  1.000 164.28976 ? 175 LYS   A HD2  1 
ATOM   2696 H HD3  . LYS   A 1 178 ? 51.04735 7.71144   8.46575  1.000 164.28976 ? 175 LYS   A HD3  1 
ATOM   2697 H HE2  . LYS   A 1 178 ? 53.30199 7.82670   8.78878  1.000 145.83409 ? 175 LYS   A HE2  1 
ATOM   2698 H HE3  . LYS   A 1 178 ? 52.81431 6.53264   9.57172  1.000 145.83409 ? 175 LYS   A HE3  1 
ATOM   2699 H HZ1  . LYS   A 1 178 ? 54.67342 6.07216   8.34022  1.000 150.80875 ? 175 LYS   A HZ1  1 
ATOM   2700 H HZ2  . LYS   A 1 178 ? 53.57477 5.27581   7.83315  1.000 150.80875 ? 175 LYS   A HZ2  1 
ATOM   2701 H HZ3  . LYS   A 1 178 ? 54.00995 6.45323   7.11022  1.000 150.80875 ? 175 LYS   A HZ3  1 
ATOM   2702 N N    . GLU   A 1 179 ? 48.02627 8.36364   7.21138  1.000 37.95548  ? 176 GLU   A N    1 
ATOM   2703 C CA   A GLU   A 1 179 ? 47.98069 9.70599   7.78117  0.456 39.79382  ? 176 GLU   A CA   1 
ATOM   2704 C CA   B GLU   A 1 179 ? 47.97832 9.70841   7.77862  0.544 39.76498  ? 176 GLU   A CA   1 
ATOM   2705 C C    . GLU   A 1 179 ? 46.74054 9.89490   8.64730  1.000 32.98331  ? 176 GLU   A C    1 
ATOM   2706 O O    . GLU   A 1 179 ? 46.82150 10.47361  9.73649  1.000 28.88268  ? 176 GLU   A O    1 
ATOM   2707 C CB   A GLU   A 1 179 ? 48.03317 10.74564  6.66187  0.456 47.25200  ? 176 GLU   A CB   1 
ATOM   2708 C CB   B GLU   A 1 179 ? 48.01337 10.75550  6.66386  0.544 47.25751  ? 176 GLU   A CB   1 
ATOM   2709 C CG   A GLU   A 1 179 ? 49.31943 10.69318  5.84543  0.456 50.22090  ? 176 GLU   A CG   1 
ATOM   2710 C CG   B GLU   A 1 179 ? 48.05456 12.19474  7.16660  0.544 52.24452  ? 176 GLU   A CG   1 
ATOM   2711 C CD   A GLU   A 1 179 ? 49.24469 11.51728  4.57522  0.456 72.08582  ? 176 GLU   A CD   1 
ATOM   2712 C CD   B GLU   A 1 179 ? 48.11292 13.20973  6.04052  0.544 70.34147  ? 176 GLU   A CD   1 
ATOM   2713 O OE1  A GLU   A 1 179 ? 48.60486 12.58998  4.59406  0.456 77.87337  ? 176 GLU   A OE1  1 
ATOM   2714 O OE1  B GLU   A 1 179 ? 47.49727 12.96573  4.98134  0.544 65.85220  ? 176 GLU   A OE1  1 
ATOM   2715 O OE2  A GLU   A 1 179 ? 49.82216 11.08718  3.55434  0.456 54.31125  ? 176 GLU   A OE2  1 
ATOM   2716 O OE2  B GLU   A 1 179 ? 48.77920 14.25180  6.21411  0.544 57.63770  ? 176 GLU   A OE2  1 
ATOM   2717 H H    A GLU   A 1 179 ? 47.87920 8.32447   6.36496  0.456 45.48095  ? 176 GLU   A H    1 
ATOM   2718 H H    B GLU   A 1 179 ? 47.88018 8.32371   6.36482  0.544 45.48095  ? 176 GLU   A H    1 
ATOM   2719 H HA   A GLU   A 1 179 ? 48.75742 9.83887   8.34679  0.456 47.68696  ? 176 GLU   A HA   1 
ATOM   2720 H HA   B GLU   A 1 179 ? 48.76205 9.83900   8.33504  0.544 47.65235  ? 176 GLU   A HA   1 
ATOM   2721 H HB2  A GLU   A 1 179 ? 47.29046 10.59224  6.05709  0.456 56.63678  ? 176 GLU   A HB2  1 
ATOM   2722 H HB2  B GLU   A 1 179 ? 48.80578 10.60857  6.12405  0.544 56.64339  ? 176 GLU   A HB2  1 
ATOM   2723 H HB3  A GLU   A 1 179 ? 47.96505 11.63059  7.05317  0.456 56.63678  ? 176 GLU   A HB3  1 
ATOM   2724 H HB3  B GLU   A 1 179 ? 47.21734 10.65594  6.11859  0.544 56.64339  ? 176 GLU   A HB3  1 
ATOM   2725 H HG2  A GLU   A 1 179 ? 50.04920 11.03781  6.38354  0.456 60.19945  ? 176 GLU   A HG2  1 
ATOM   2726 H HG2  B GLU   A 1 179 ? 47.25527 12.37044  7.68732  0.544 62.62779  ? 176 GLU   A HG2  1 
ATOM   2727 H HG3  A GLU   A 1 179 ? 49.49737 9.77300   5.59541  0.456 60.19945  ? 176 GLU   A HG3  1 
ATOM   2728 H HG3  B GLU   A 1 179 ? 48.84311 12.31402  7.71875  0.544 62.62779  ? 176 GLU   A HG3  1 
ATOM   2729 N N    . VAL   A 1 180 ? 45.58567 9.40820   8.18720  1.000 27.79361  ? 177 VAL   A N    1 
ATOM   2730 C CA   . VAL   A 1 180 ? 44.36910 9.52600   8.98653  1.000 30.56684  ? 177 VAL   A CA   1 
ATOM   2731 C C    . VAL   A 1 180 ? 44.50547 8.73144   10.27894 1.000 27.97431  ? 177 VAL   A C    1 
ATOM   2732 O O    . VAL   A 1 180 ? 44.11761 9.19816   11.35743 1.000 24.33399  ? 177 VAL   A O    1 
ATOM   2733 C CB   . VAL   A 1 180 ? 43.14434 9.07256   8.17129  1.000 32.81135  ? 177 VAL   A CB   1 
ATOM   2734 C CG1  . VAL   A 1 180 ? 41.91916 8.96709   9.06784  1.000 28.09449  ? 177 VAL   A CG1  1 
ATOM   2735 C CG2  . VAL   A 1 180 ? 42.88609 10.04047  7.02847  1.000 32.23335  ? 177 VAL   A CG2  1 
ATOM   2736 H H    . VAL   A 1 180 ? 45.48298 9.01329   7.43017  1.000 33.28670  ? 177 VAL   A H    1 
ATOM   2737 H HA   . VAL   A 1 180 ? 44.24374 10.45939  9.21886  1.000 36.61458  ? 177 VAL   A HA   1 
ATOM   2738 H HB   . VAL   A 1 180 ? 43.32091 8.19587   7.79563  1.000 39.30799  ? 177 VAL   A HB   1 
ATOM   2739 H HG11 . VAL   A 1 180 ? 41.12309 8.94911   8.51391  1.000 33.64776  ? 177 VAL   A HG11 1 
ATOM   2740 H HG12 . VAL   A 1 180 ? 41.97826 8.15090   9.58863  1.000 33.64776  ? 177 VAL   A HG12 1 
ATOM   2741 H HG13 . VAL   A 1 180 ? 41.89342 9.73562   9.65912  1.000 33.64776  ? 177 VAL   A HG13 1 
ATOM   2742 H HG21 . VAL   A 1 180 ? 42.13170 9.72148   6.50882  1.000 38.61440  ? 177 VAL   A HG21 1 
ATOM   2743 H HG22 . VAL   A 1 180 ? 42.68841 10.91648  7.39513  1.000 38.61440  ? 177 VAL   A HG22 1 
ATOM   2744 H HG23 . VAL   A 1 180 ? 43.67716 10.08686  6.46905  1.000 38.61440  ? 177 VAL   A HG23 1 
ATOM   2745 N N    . ALA   A 1 181 ? 45.05695 7.51905   10.19305 1.000 27.60983  ? 178 ALA   A N    1 
ATOM   2746 C CA   . ALA   A 1 181 ? 45.26395 6.71866   11.39492 1.000 26.65206  ? 178 ALA   A CA   1 
ATOM   2747 C C    . ALA   A 1 181 ? 46.14522 7.45311   12.39711 1.000 31.95692  ? 178 ALA   A C    1 
ATOM   2748 O O    . ALA   A 1 181 ? 45.88946 7.41568   13.60657 1.000 25.82486  ? 178 ALA   A O    1 
ATOM   2749 C CB   . ALA   A 1 181 ? 45.88282 5.37080   11.02650 1.000 30.62641  ? 178 ALA   A CB   1 
ATOM   2750 H H    . ALA   A 1 181 ? 45.31496 7.14489   9.46296  1.000 33.06617  ? 178 ALA   A H    1 
ATOM   2751 H HA   . ALA   A 1 181 ? 44.40453 6.55132   11.81242 1.000 31.91685  ? 178 ALA   A HA   1 
ATOM   2752 H HB1  . ALA   A 1 181 ? 46.01320 4.85151   11.83535 1.000 36.68607  ? 178 ALA   A HB1  1 
ATOM   2753 H HB2  . ALA   A 1 181 ? 45.28323 4.90175   10.42534 1.000 36.68607  ? 178 ALA   A HB2  1 
ATOM   2754 H HB3  . ALA   A 1 181 ? 46.73569 5.52354   10.59040 1.000 36.68607  ? 178 ALA   A HB3  1 
ATOM   2755 N N    . ALA   A 1 182 ? 47.18812 8.13060   11.91148 1.000 26.53321  ? 179 ALA   A N    1 
ATOM   2756 C CA   . ALA   A 1 182 ? 48.07714 8.86022   12.80827 1.000 27.74884  ? 179 ALA   A CA   1 
ATOM   2757 C C    . ALA   A 1 182 ? 47.37092 10.05655  13.43372 1.000 29.14653  ? 179 ALA   A C    1 
ATOM   2758 O O    . ALA   A 1 182 ? 47.56430 10.34662  14.62023 1.000 29.51450  ? 179 ALA   A O    1 
ATOM   2759 C CB   . ALA   A 1 182 ? 49.32810 9.30837   12.05363 1.000 28.74886  ? 179 ALA   A CB   1 
ATOM   2760 H H    . ALA   A 1 182 ? 47.39802 8.18172   11.07906 1.000 31.77422  ? 179 ALA   A H    1 
ATOM   2761 H HA   . ALA   A 1 182 ? 48.35416 8.26775   13.52460 1.000 33.23299  ? 179 ALA   A HA   1 
ATOM   2762 H HB1  . ALA   A 1 182 ? 49.90648 9.79475   12.66175 1.000 34.43300  ? 179 ALA   A HB1  1 
ATOM   2763 H HB2  . ALA   A 1 182 ? 49.78915 8.52562   11.71357 1.000 34.43300  ? 179 ALA   A HB2  1 
ATOM   2764 H HB3  . ALA   A 1 182 ? 49.06424 9.88257   11.31772 1.000 34.43300  ? 179 ALA   A HB3  1 
ATOM   2765 N N    . GLN   A 1 183 ? 46.54990 10.76504  12.65434 1.000 25.13001  ? 180 GLN   A N    1 
ATOM   2766 C CA   A GLN   A 1 183 ? 45.80869 11.90821  13.18352 0.565 29.07709  ? 180 GLN   A CA   1 
ATOM   2767 C CA   B GLN   A 1 183 ? 45.84278 11.90928  13.21532 0.435 29.07970  ? 180 GLN   A CA   1 
ATOM   2768 C C    . GLN   A 1 183 ? 44.80129 11.46935  14.23877 1.000 24.64131  ? 180 GLN   A C    1 
ATOM   2769 O O    . GLN   A 1 183 ? 44.63498 12.12751  15.27274 1.000 25.90208  ? 180 GLN   A O    1 
ATOM   2770 C CB   A GLN   A 1 183 ? 45.08618 12.63651  12.04764 0.565 29.82386  ? 180 GLN   A CB   1 
ATOM   2771 C CB   B GLN   A 1 183 ? 45.20680 12.73333  12.09778 0.435 29.93266  ? 180 GLN   A CB   1 
ATOM   2772 C CG   A GLN   A 1 183 ? 45.99072 13.23505  10.97983 0.565 33.29699  ? 180 GLN   A CG   1 
ATOM   2773 C CG   B GLN   A 1 183 ? 46.21938 13.54555  11.29847 0.435 33.58007  ? 180 GLN   A CG   1 
ATOM   2774 C CD   A GLN   A 1 183 ? 45.22420 13.62435  9.72393  0.565 36.53867  ? 180 GLN   A CD   1 
ATOM   2775 C CD   B GLN   A 1 183 ? 46.99046 14.53113  12.16076 0.435 35.70481  ? 180 GLN   A CD   1 
ATOM   2776 O OE1  A GLN   A 1 183 ? 44.03185 13.34060  9.59546  0.565 31.19145  ? 180 GLN   A OE1  1 
ATOM   2777 O OE1  B GLN   A 1 183 ? 46.40462 15.40577  12.79931 0.435 30.61731  ? 180 GLN   A OE1  1 
ATOM   2778 N NE2  A GLN   A 1 183 ? 45.90653 14.27935  8.79351  0.565 43.45875  ? 180 GLN   A NE2  1 
ATOM   2779 N NE2  B GLN   A 1 183 ? 48.31073 14.38465  12.19199 0.435 40.54346  ? 180 GLN   A NE2  1 
ATOM   2780 H H    A GLN   A 1 183 ? 46.40575 10.60521  11.82171 0.565 30.09038  ? 180 GLN   A H    1 
ATOM   2781 H H    B GLN   A 1 183 ? 46.39168 10.60677  11.82397 0.435 30.09038  ? 180 GLN   A H    1 
ATOM   2782 H HA   A GLN   A 1 183 ? 46.43822 12.52243  13.59257 0.565 34.82688  ? 180 GLN   A HA   1 
ATOM   2783 H HA   B GLN   A 1 183 ? 46.47990 12.47996  13.67282 0.435 34.83001  ? 180 GLN   A HA   1 
ATOM   2784 H HB2  A GLN   A 1 183 ? 44.49575 12.00576  11.60668 0.565 35.72300  ? 180 GLN   A HB2  1 
ATOM   2785 H HB2  B GLN   A 1 183 ? 44.75435 12.13358  11.48419 0.435 35.85356  ? 180 GLN   A HB2  1 
ATOM   2786 H HB3  A GLN   A 1 183 ? 44.56956 13.36302  12.42998 0.565 35.72300  ? 180 GLN   A HB3  1 
ATOM   2787 H HB3  B GLN   A 1 183 ? 44.56937 13.35180  12.48775 0.435 35.85356  ? 180 GLN   A HB3  1 
ATOM   2788 H HG2  A GLN   A 1 183 ? 46.41520 14.03233  11.33348 0.565 39.89076  ? 180 GLN   A HG2  1 
ATOM   2789 H HG2  B GLN   A 1 183 ? 46.85792 12.94083  10.88923 0.435 40.23046  ? 180 GLN   A HG2  1 
ATOM   2790 H HG3  A GLN   A 1 183 ? 46.66442 12.58266  10.73201 0.565 39.89076  ? 180 GLN   A HG3  1 
ATOM   2791 H HG3  B GLN   A 1 183 ? 45.75182 14.04791  10.61297 0.435 40.23046  ? 180 GLN   A HG3  1 
ATOM   2792 H HE21 A GLN   A 1 183 ? 46.73758 14.46199  8.91838  0.565 52.08488  ? 180 GLN   A HE21 1 
ATOM   2793 H HE21 B GLN   A 1 183 ? 48.68454 13.75667  11.73867 0.435 48.58652  ? 180 GLN   A HE21 1 
ATOM   2794 H HE22 A GLN   A 1 183 ? 45.51776 14.52129  8.06555  0.565 52.08488  ? 180 GLN   A HE22 1 
ATOM   2795 H HE22 B GLN   A 1 183 ? 48.79144 14.91783  12.66553 0.435 48.58652  ? 180 GLN   A HE22 1 
ATOM   2796 N N    . VAL   A 1 184 ? 44.10398 10.36112  13.98227 1.000 25.45073  ? 181 VAL   A N    1 
ATOM   2797 C CA   . VAL   A 1 184 ? 43.13825 9.85305   14.94965 1.000 25.57884  ? 181 VAL   A CA   1 
ATOM   2798 C C    . VAL   A 1 184 ? 43.84425 9.35027   16.20247 1.000 24.48795  ? 181 VAL   A C    1 
ATOM   2799 O O    . VAL   A 1 184 ? 43.29926 9.42979   17.30921 1.000 22.31851  ? 181 VAL   A O    1 
ATOM   2800 C CB   . VAL   A 1 184 ? 42.28594 8.74342   14.30631 1.000 26.09123  ? 181 VAL   A CB   1 
ATOM   2801 C CG1  . VAL   A 1 184 ? 41.53735 7.95922   15.37394 1.000 29.12757  ? 181 VAL   A CG1  1 
ATOM   2802 C CG2  . VAL   A 1 184 ? 41.31926 9.33826   13.29500 1.000 27.95413  ? 181 VAL   A CG2  1 
ATOM   2803 H H    . VAL   A 1 184 ? 44.17162 9.89213   13.26458 1.000 30.47525  ? 181 VAL   A H    1 
ATOM   2804 H HA   . VAL   A 1 184 ? 42.54993 10.57896  15.21013 1.000 30.62898  ? 181 VAL   A HA   1 
ATOM   2805 H HB   . VAL   A 1 184 ? 42.87066 8.12722   13.83801 1.000 31.24385  ? 181 VAL   A HB   1 
ATOM   2806 H HG11 . VAL   A 1 184 ? 40.80941 7.47280   14.95632 1.000 34.88746  ? 181 VAL   A HG11 1 
ATOM   2807 H HG12 . VAL   A 1 184 ? 42.15024 7.33802   15.79747 1.000 34.88746  ? 181 VAL   A HG12 1 
ATOM   2808 H HG13 . VAL   A 1 184 ? 41.18629 8.57856   16.03278 1.000 34.88746  ? 181 VAL   A HG13 1 
ATOM   2809 H HG21 . VAL   A 1 184 ? 40.79215 8.62399   12.90400 1.000 33.47933  ? 181 VAL   A HG21 1 
ATOM   2810 H HG22 . VAL   A 1 184 ? 40.73759 9.96910   13.74733 1.000 33.47933  ? 181 VAL   A HG22 1 
ATOM   2811 H HG23 . VAL   A 1 184 ? 41.82559 9.79239   12.60341 1.000 33.47933  ? 181 VAL   A HG23 1 
ATOM   2812 N N    . LYS   A 1 185 ? 45.06573 8.84073   16.05725 1.000 23.75502  ? 182 LYS   A N    1 
ATOM   2813 C CA   . LYS   A 1 185 ? 45.75336 8.21426   17.18098 1.000 25.33452  ? 182 LYS   A CA   1 
ATOM   2814 C C    . LYS   A 1 185 ? 46.19297 9.23605   18.22605 1.000 27.28693  ? 182 LYS   A C    1 
ATOM   2815 O O    . LYS   A 1 185 ? 46.15822 8.95757   19.43103 1.000 23.45756  ? 182 LYS   A O    1 
ATOM   2816 C CB   . LYS   A 1 185 ? 46.95702 7.43516   16.65829 1.000 23.12554  ? 182 LYS   A CB   1 
ATOM   2817 C CG   . LYS   A 1 185 ? 47.81420 6.80607   17.73215 1.000 31.11006  ? 182 LYS   A CG   1 
ATOM   2818 C CD   . LYS   A 1 185 ? 49.01171 6.09666   17.12149 1.000 36.27240  ? 182 LYS   A CD   1 
ATOM   2819 C CE   . LYS   A 1 185 ? 49.90595 5.48759   18.19136 1.000 56.68687  ? 182 LYS   A CE   1 
ATOM   2820 N NZ   . LYS   A 1 185 ? 51.08803 4.81241   17.59489 1.000 62.40891  ? 182 LYS   A NZ   1 
ATOM   2821 N N    . ALA   A 1 186 ? 46.63698 10.41006  17.78918 1.000 24.54637  ? 183 ALA   A N    1 
ATOM   2822 C CA   . ALA   A 1 186 ? 47.31723 11.32132  18.70683 1.000 27.41943  ? 183 ALA   A CA   1 
ATOM   2823 C C    . ALA   A 1 186 ? 46.45415 11.74157  19.89107 1.000 24.22556  ? 183 ALA   A C    1 
ATOM   2824 O O    . ALA   A 1 186 ? 46.95611 11.72256  21.02898 1.000 32.71331  ? 183 ALA   A O    1 
ATOM   2825 C CB   . ALA   A 1 186 ? 47.82046 12.53979  17.92614 1.000 27.68222  ? 183 ALA   A CB   1 
ATOM   2826 H H    . ALA   A 1 186 ? 46.55985 10.69936  16.98298 1.000 29.39002  ? 183 ALA   A H    1 
ATOM   2827 H HA   . ALA   A 1 186 ? 48.08137 10.84688  19.07000 1.000 32.83769  ? 183 ALA   A HA   1 
ATOM   2828 H HB1  . ALA   A 1 186 ? 48.25136 13.15328  18.54165 1.000 33.15303  ? 183 ALA   A HB1  1 
ATOM   2829 H HB2  . ALA   A 1 186 ? 48.45525 12.24454  17.25475 1.000 33.15303  ? 183 ALA   A HB2  1 
ATOM   2830 H HB3  . ALA   A 1 186 ? 47.06596 12.97500  17.49928 1.000 33.15303  ? 183 ALA   A HB3  1 
ATOM   2831 N N    . PRO   A 1 187 ? 45.18433 12.12628  19.72011 1.000 25.98079  ? 184 PRO   A N    1 
ATOM   2832 C CA   . PRO   A 1 187 ? 44.39525 12.56951  20.88124 1.000 23.02796  ? 184 PRO   A CA   1 
ATOM   2833 C C    . PRO   A 1 187 ? 44.02904 11.45091  21.84441 1.000 22.91893  ? 184 PRO   A C    1 
ATOM   2834 O O    . PRO   A 1 187 ? 43.46863 11.74195  22.90830 1.000 24.55732  ? 184 PRO   A O    1 
ATOM   2835 C CB   . PRO   A 1 187 ? 43.13526 13.18050  20.24469 1.000 22.86321  ? 184 PRO   A CB   1 
ATOM   2836 C CG   . PRO   A 1 187 ? 43.45567 13.35782  18.79393 1.000 26.48452  ? 184 PRO   A CG   1 
ATOM   2837 C CD   . PRO   A 1 187 ? 44.43268 12.27876  18.46381 1.000 24.09124  ? 184 PRO   A CD   1 
ATOM   2838 H HA   . PRO   A 1 187 ? 44.87866 13.25980  21.36157 1.000 27.56792  ? 184 PRO   A HA   1 
ATOM   2839 H HB2  . PRO   A 1 187 ? 42.38516 12.57638  20.36005 1.000 27.37023  ? 184 PRO   A HB2  1 
ATOM   2840 H HB3  . PRO   A 1 187 ? 42.94033 14.03470  20.66091 1.000 27.37023  ? 184 PRO   A HB3  1 
ATOM   2841 H HG2  . PRO   A 1 187 ? 42.64760 13.26429  18.26555 1.000 31.71580  ? 184 PRO   A HG2  1 
ATOM   2842 H HG3  . PRO   A 1 187 ? 43.84737 14.23329  18.64897 1.000 31.71580  ? 184 PRO   A HG3  1 
ATOM   2843 H HD2  . PRO   A 1 187 ? 43.97549 11.45569  18.23047 1.000 28.84386  ? 184 PRO   A HD2  1 
ATOM   2844 H HD3  . PRO   A 1 187 ? 45.01810 12.54991  17.73947 1.000 28.84386  ? 184 PRO   A HD3  1 
ATOM   2845 N N    . LEU   A 1 188 ? 44.32173 10.19157  21.51651 1.000 22.33721  ? 185 LEU   A N    1 
ATOM   2846 C CA   . LEU   A 1 188 ? 43.93983 9.08119   22.38082 1.000 24.62435  ? 185 LEU   A CA   1 
ATOM   2847 C C    . LEU   A 1 188 ? 44.88393 8.89647   23.56236 1.000 27.50296  ? 185 LEU   A C    1 
ATOM   2848 O O    . LEU   A 1 188 ? 44.50569 8.25149   24.54643 1.000 23.56681  ? 185 LEU   A O    1 
ATOM   2849 C CB   . LEU   A 1 188 ? 43.88491 7.78476   21.57061 1.000 25.38048  ? 185 LEU   A CB   1 
ATOM   2850 C CG   . LEU   A 1 188 ? 42.87976 7.74374   20.41811 1.000 20.56639  ? 185 LEU   A CG   1 
ATOM   2851 C CD1  . LEU   A 1 188 ? 43.04082 6.45872   19.62046 1.000 22.94191  ? 185 LEU   A CD1  1 
ATOM   2852 C CD2  . LEU   A 1 188 ? 41.45788 7.87059   20.93969 1.000 24.92645  ? 185 LEU   A CD2  1 
ATOM   2853 H H    . LEU   A 1 188 ? 44.73884 9.95716   20.80190 1.000 26.73902  ? 185 LEU   A H    1 
ATOM   2854 H HA   . LEU   A 1 188 ? 43.05407 9.25832   22.73433 1.000 29.48359  ? 185 LEU   A HA   1 
ATOM   2855 H HB2  . LEU   A 1 188 ? 44.76328 7.63149   21.18867 1.000 30.39095  ? 185 LEU   A HB2  1 
ATOM   2856 H HB3  . LEU   A 1 188 ? 43.65532 7.06185   22.17525 1.000 30.39095  ? 185 LEU   A HB3  1 
ATOM   2857 H HG   . LEU   A 1 188 ? 43.04913 8.49333   19.82624 1.000 24.61404  ? 185 LEU   A HG   1 
ATOM   2858 H HD11 . LEU   A 1 188 ? 42.41744 6.46805   18.87735 1.000 27.46467  ? 185 LEU   A HD11 1 
ATOM   2859 H HD12 . LEU   A 1 188 ? 43.95062 6.40511   19.28835 1.000 27.46467  ? 185 LEU   A HD12 1 
ATOM   2860 H HD13 . LEU   A 1 188 ? 42.85473 5.70258   20.19884 1.000 27.46467  ? 185 LEU   A HD13 1 
ATOM   2861 H HD21 . LEU   A 1 188 ? 40.83921 7.75322   20.20188 1.000 29.84612  ? 185 LEU   A HD21 1 
ATOM   2862 H HD22 . LEU   A 1 188 ? 41.30560 7.18716   21.61098 1.000 29.84612  ? 185 LEU   A HD22 1 
ATOM   2863 H HD23 . LEU   A 1 188 ? 41.34249 8.75048   21.33134 1.000 29.84612  ? 185 LEU   A HD23 1 
ATOM   2864 N N    . VAL   A 1 189 ? 46.09365 9.44569   23.48952 1.000 21.06891  ? 186 VAL   A N    1 
ATOM   2865 C CA   . VAL   A 1 189 ? 47.10189 9.27255   24.52961 1.000 25.35949  ? 186 VAL   A CA   1 
ATOM   2866 C C    . VAL   A 1 189 ? 47.45960 7.79604   24.65158 1.000 30.17586  ? 186 VAL   A C    1 
ATOM   2867 O O    . VAL   A 1 189 ? 47.47814 7.23736   25.75451 1.000 23.60609  ? 186 VAL   A O    1 
ATOM   2868 C CB   . VAL   A 1 189 ? 46.62886 9.83337   25.88361 1.000 27.59745  ? 186 VAL   A CB   1 
ATOM   2869 C CG1  . VAL   A 1 189 ? 47.81755 10.01128  26.82161 1.000 25.11809  ? 186 VAL   A CG1  1 
ATOM   2870 C CG2  . VAL   A 1 189 ? 45.89338 11.15126  25.69563 1.000 22.50387  ? 186 VAL   A CG2  1 
ATOM   2871 H H    . VAL   A 1 189 ? 46.35988 9.93353   22.83322 1.000 25.21706  ? 186 VAL   A H    1 
ATOM   2872 H HA   . VAL   A 1 189 ? 47.89763 9.75986   24.26459 1.000 30.36576  ? 186 VAL   A HA   1 
ATOM   2873 H HB   . VAL   A 1 189 ? 46.01043 9.20347   26.28571 1.000 33.05132  ? 186 VAL   A HB   1 
ATOM   2874 H HG11 . VAL   A 1 189 ? 47.51400 10.43631  27.63899 1.000 30.07608  ? 186 VAL   A HG11 1 
ATOM   2875 H HG12 . VAL   A 1 189 ? 48.19480 9.14041   27.02202 1.000 30.07608  ? 186 VAL   A HG12 1 
ATOM   2876 H HG13 . VAL   A 1 189 ? 48.48251 10.56768  26.38670 1.000 30.07608  ? 186 VAL   A HG13 1 
ATOM   2877 H HG21 . VAL   A 1 189 ? 45.74944 11.55921  26.56382 1.000 26.93902  ? 186 VAL   A HG21 1 
ATOM   2878 H HG22 . VAL   A 1 189 ? 46.43146 11.73676  25.14016 1.000 26.93902  ? 186 VAL   A HG22 1 
ATOM   2879 H HG23 . VAL   A 1 189 ? 45.04108 10.97876  25.26582 1.000 26.93902  ? 186 VAL   A HG23 1 
ATOM   2880 N N    . LEU   A 1 190 ? 47.73966 7.15563   23.52034 1.000 32.19048  ? 187 LEU   A N    1 
ATOM   2881 C CA   . LEU   A 1 190 ? 48.28690 5.80767   23.52658 1.000 35.35240  ? 187 LEU   A CA   1 
ATOM   2882 C C    . LEU   A 1 190 ? 49.78375 5.85490   23.80856 1.000 37.06881  ? 187 LEU   A C    1 
ATOM   2883 O O    . LEU   A 1 190 ? 50.46345 6.83880   23.50342 1.000 47.61056  ? 187 LEU   A O    1 
ATOM   2884 C CB   . LEU   A 1 190 ? 48.02813 5.11644   22.18909 1.000 31.56686  ? 187 LEU   A CB   1 
ATOM   2885 C CG   . LEU   A 1 190 ? 46.57459 4.72151   21.92979 1.000 32.73272  ? 187 LEU   A CG   1 
ATOM   2886 C CD1  . LEU   A 1 190 ? 46.38288 4.32574   20.47812 1.000 34.27959  ? 187 LEU   A CD1  1 
ATOM   2887 C CD2  . LEU   A 1 190 ? 46.16480 3.58830   22.85515 1.000 33.98793  ? 187 LEU   A CD2  1 
ATOM   2888 H H    . LEU   A 1 190 ? 47.62067 7.48294   22.73402 1.000 38.56295  ? 187 LEU   A H    1 
ATOM   2889 H HA   . LEU   A 1 190 ? 47.85795 5.28144   24.21939 1.000 42.35725  ? 187 LEU   A HA   1 
ATOM   2890 H HB2  . LEU   A 1 190 ? 48.29699 5.71815   21.47736 1.000 37.81460  ? 187 LEU   A HB2  1 
ATOM   2891 H HB3  . LEU   A 1 190 ? 48.55960 4.30565   22.15655 1.000 37.81460  ? 187 LEU   A HB3  1 
ATOM   2892 H HG   . LEU   A 1 190 ? 45.99925 5.48144   22.10975 1.000 39.21363  ? 187 LEU   A HG   1 
ATOM   2893 H HD11 . LEU   A 1 190 ? 45.48891 3.96699   20.36402 1.000 41.06988  ? 187 LEU   A HD11 1 
ATOM   2894 H HD12 . LEU   A 1 190 ? 46.49843 5.10998   19.91908 1.000 41.06988  ? 187 LEU   A HD12 1 
ATOM   2895 H HD13 . LEU   A 1 190 ? 47.04155 3.65307   20.24456 1.000 41.06988  ? 187 LEU   A HD13 1 
ATOM   2896 H HD21 . LEU   A 1 190 ? 45.28465 3.27254   22.59721 1.000 40.71989  ? 187 LEU   A HD21 1 
ATOM   2897 H HD22 . LEU   A 1 190 ? 46.81027 2.86838   22.77788 1.000 40.71989  ? 187 LEU   A HD22 1 
ATOM   2898 H HD23 . LEU   A 1 190 ? 46.14394 3.91736   23.76739 1.000 40.71989  ? 187 LEU   A HD23 1 
ATOM   2899 N N    . LYS   A 1 191 ? 50.29829 4.77637   24.40106 1.000 47.09448  ? 188 LYS   A N    1 
ATOM   2900 C CA   . LYS   A 1 191 ? 51.71188 4.74695   24.76276 1.000 62.09043  ? 188 LYS   A CA   1 
ATOM   2901 C C    . LYS   A 1 191 ? 52.59035 4.66369   23.51917 1.000 64.35734  ? 188 LYS   A C    1 
ATOM   2902 O O    . LYS   A 1 191 ? 53.46164 5.51366   23.30011 1.000 76.17906  ? 188 LYS   A O    1 
ATOM   2903 C CB   . LYS   A 1 191 ? 51.99383 3.57790   25.71069 1.000 60.61538  ? 188 LYS   A CB   1 
ATOM   2904 C CG   . LYS   A 1 191 ? 53.37838 3.64949   26.34748 1.000 66.79288  ? 188 LYS   A CG   1 
ATOM   2905 C CD   . LYS   A 1 191 ? 53.41806 3.07308   27.76215 1.000 76.88741  ? 188 LYS   A CD   1 
ATOM   2906 C CE   . LYS   A 1 191 ? 53.83011 1.60792   27.78384 1.000 125.56169 ? 188 LYS   A CE   1 
ATOM   2907 N NZ   . LYS   A 1 191 ? 54.58855 1.28043   29.02562 1.000 111.72301 ? 188 LYS   A NZ   1 
ATOM   2908 H H    . LYS   A 1 191 ? 49.85862 4.06447   24.59975 1.000 56.44775  ? 188 LYS   A H    1 
ATOM   2909 H HA   . LYS   A 1 191 ? 51.93022 5.56685   25.23286 1.000 74.44289  ? 188 LYS   A HA   1 
ATOM   2910 H HB2  . LYS   A 1 191 ? 51.33563 3.58432   26.42317 1.000 72.67283  ? 188 LYS   A HB2  1 
ATOM   2911 H HB3  . LYS   A 1 191 ? 51.93562 2.74752   25.21272 1.000 72.67283  ? 188 LYS   A HB3  1 
ATOM   2912 H HG2  . LYS   A 1 191 ? 54.00244 3.14510   25.80248 1.000 80.08583  ? 188 LYS   A HG2  1 
ATOM   2913 H HG3  . LYS   A 1 191 ? 53.65539 4.57783   26.39598 1.000 80.08583  ? 188 LYS   A HG3  1 
ATOM   2914 H HD2  . LYS   A 1 191 ? 54.05926 3.57338   28.29079 1.000 92.19926  ? 188 LYS   A HD2  1 
ATOM   2915 H HD3  . LYS   A 1 191 ? 52.53531 3.14283   28.15811 1.000 92.19926  ? 188 LYS   A HD3  1 
ATOM   2916 H HE2  . LYS   A 1 191 ? 53.03753 1.04957   27.75255 1.000 150.60841 ? 188 LYS   A HE2  1 
ATOM   2917 H HE3  . LYS   A 1 191 ? 54.39779 1.42127   27.01977 1.000 150.60841 ? 188 LYS   A HE3  1 
ATOM   2918 H HZ1  . LYS   A 1 191 ? 54.81065 0.41859   29.02829 1.000 134.00198 ? 188 LYS   A HZ1  1 
ATOM   2919 H HZ2  . LYS   A 1 191 ? 55.33060 1.77006   29.06713 1.000 134.00198 ? 188 LYS   A HZ2  1 
ATOM   2920 H HZ3  . LYS   A 1 191 ? 54.08878 1.45213   29.74175 1.000 134.00198 ? 188 LYS   A HZ3  1 
ATOM   2921 N N    . ASP   A 1 192 ? 52.37322 3.64649   22.69101 1.000 62.54774  ? 189 ASP   A N    1 
ATOM   2922 C CA   . ASP   A 1 192 ? 53.14541 3.47684   21.46381 1.000 97.12395  ? 189 ASP   A CA   1 
ATOM   2923 C C    . ASP   A 1 192 ? 52.22847 3.31984   20.25601 1.000 87.78097  ? 189 ASP   A C    1 
ATOM   2924 O O    . ASP   A 1 192 ? 52.25322 4.13878   19.33766 1.000 82.23632  ? 189 ASP   A O    1 
ATOM   2925 C CB   . ASP   A 1 192 ? 54.07249 2.26585   21.57942 1.000 78.60869  ? 189 ASP   A CB   1 
ATOM   2926 C CG   . ASP   A 1 192 ? 55.20389 2.49107   22.56310 1.000 106.65435 ? 189 ASP   A CG   1 
ATOM   2927 O OD1  . ASP   A 1 192 ? 55.75038 3.61415   22.59711 1.000 107.15383 ? 189 ASP   A OD1  1 
ATOM   2928 O OD2  . ASP   A 1 192 ? 55.54538 1.54596   23.30432 1.000 113.58543 ? 189 ASP   A OD2  1 
ATOM   2929 H H    . ASP   A 1 192 ? 51.78030 3.03661   22.81789 1.000 74.99166  ? 189 ASP   A H    1 
ATOM   2930 H HA   . ASP   A 1 192 ? 53.69317 4.26510   21.32413 1.000 116.48311 ? 189 ASP   A HA   1 
ATOM   2931 H HB2  . ASP   A 1 192 ? 53.55842 1.50106   21.88228 1.000 94.26480  ? 189 ASP   A HB2  1 
ATOM   2932 H HB3  . ASP   A 1 192 ? 54.46183 2.08081   20.71047 1.000 94.26480  ? 189 ASP   A HB3  1 
HETATM 2933 O O    . HOH   B 2 .   ? 48.40567 -0.07372  11.30168 1.000 64.16153  ? 301 HOH   A O    1 
HETATM 2934 O O    . HOH   B 2 .   ? 45.96133 -1.82497  21.62504 1.000 29.42698  ? 302 HOH   A O    1 
HETATM 2935 O O    . HOH   B 2 .   ? 13.87034 -2.04481  9.68026  1.000 69.19038  ? 303 HOH   A O    1 
HETATM 2936 O O    . HOH   B 2 .   ? 30.09524 -6.21073  2.70336  1.000 42.84271  ? 304 HOH   A O    1 
HETATM 2937 O O    . HOH   B 2 .   ? 25.25780 1.33562   20.20257 1.000 30.84777  ? 305 HOH   A O    1 
HETATM 2938 O O    . HOH   B 2 .   ? 49.12437 -24.14978 8.59937  1.000 28.85390  ? 306 HOH   A O    1 
HETATM 2939 O O    . HOH   B 2 .   ? 48.525   -11.900   1.502    1.000 66.73891  ? 307 HOH   A O    1 
HETATM 2940 O O    . HOH   B 2 .   ? 25.95437 2.96883   17.76377 1.000 26.26982  ? 308 HOH   A O    1 
HETATM 2941 O O    . HOH   B 2 .   ? 16.82019 -2.33878  12.09766 1.000 43.39316  ? 309 HOH   A O    1 
HETATM 2942 O O    . HOH   B 2 .   ? 37.60171 -3.11976  1.72645  1.000 36.65494  ? 310 HOH   A O    1 
HETATM 2943 O O    . HOH   B 2 .   ? 46.271   -28.288   14.240   1.000 30.05298  ? 311 HOH   A O    1 
HETATM 2944 O O    . HOH   B 2 .   ? 52.09239 -7.56285  12.42787 1.000 55.79373  ? 312 HOH   A O    1 
HETATM 2945 O O    . HOH   B 2 .   ? 43.83130 -13.55956 3.03499  1.000 58.59892  ? 313 HOH   A O    1 
HETATM 2946 O O    . HOH   B 2 .   ? 41.59350 -23.19668 21.93276 1.000 36.85398  ? 314 HOH   A O    1 
HETATM 2947 O O    . HOH   B 2 .   ? 47.35474 -25.41293 18.40009 1.000 40.17476  ? 315 HOH   A O    1 
HETATM 2948 O O    . HOH   B 2 .   ? 21.43444 -15.71829 12.70960 1.000 42.70769  ? 316 HOH   A O    1 
HETATM 2949 O O    . HOH   B 2 .   ? 35.20066 -25.52476 9.25074  1.000 43.05738  ? 317 HOH   A O    1 
HETATM 2950 O O    . HOH   B 2 .   ? 14.48885 -6.05291  11.06858 1.000 56.86341  ? 318 HOH   A O    1 
HETATM 2951 O O    . HOH   B 2 .   ? 31.59152 -11.77041 19.15571 1.000 25.87986  ? 319 HOH   A O    1 
HETATM 2952 O O    . HOH   B 2 .   ? 28.42283 -13.32569 30.83500 1.000 60.19195  ? 320 HOH   A O    1 
HETATM 2953 O O    . HOH   B 2 .   ? 46.301   -29.938   7.570    1.000 21.65338  ? 321 HOH   A O    1 
HETATM 2954 O O    . HOH   B 2 .   ? 45.55710 14.69895  15.44210 1.000 35.63596  ? 322 HOH   A O    1 
HETATM 2955 O O    . HOH   B 2 .   ? 27.65043 1.91960   7.83567  1.000 40.80296  ? 323 HOH   A O    1 
HETATM 2956 O O    . HOH   B 2 .   ? 13.87636 -0.92238  13.55289 1.000 79.29232  ? 324 HOH   A O    1 
HETATM 2957 O O    . HOH   B 2 .   ? 51.32996 9.27507   24.44304 1.000 54.61438  ? 325 HOH   A O    1 
HETATM 2958 O O    . HOH   B 2 .   ? 34.81554 -22.15621 15.31034 1.000 48.05007  ? 326 HOH   A O    1 
HETATM 2959 O O    . HOH   B 2 .   ? 45.55445 8.81170   5.23234  1.000 38.33844  ? 327 HOH   A O    1 
HETATM 2960 O O    . HOH   B 2 .   ? 38.56096 -28.05473 11.00228 1.000 42.11541  ? 328 HOH   A O    1 
HETATM 2961 O O    . HOH   B 2 .   ? 38.91465 -17.56932 26.77824 1.000 40.79665  ? 329 HOH   A O    1 
HETATM 2962 O O    . HOH   B 2 .   ? 39.11678 -18.62222 23.78932 1.000 55.38770  ? 330 HOH   A O    1 
HETATM 2963 O O    . HOH   B 2 .   ? 23.71513 -17.85544 16.24082 1.000 41.99278  ? 331 HOH   A O    1 
HETATM 2964 O O    . HOH   B 2 .   ? 22.07136 -9.87791  18.79460 1.000 29.18154  ? 332 HOH   A O    1 
HETATM 2965 O O    . HOH   B 2 .   ? 45.11533 -12.24709 9.80721  1.000 21.62499  ? 333 HOH   A O    1 
HETATM 2966 O O    . HOH   B 2 .   ? 31.95123 10.34488  13.16161 1.000 32.82557  ? 334 HOH   A O    1 
HETATM 2967 O O    . HOH   B 2 .   ? 39.13305 -30.02420 8.61674  1.000 53.44834  ? 335 HOH   A O    1 
HETATM 2968 O O    . HOH   B 2 .   ? 29.55939 -10.14592 18.41546 1.000 23.34780  ? 336 HOH   A O    1 
HETATM 2969 O O    . HOH   B 2 .   ? 31.73142 -14.50353 26.27848 1.000 22.40204  ? 337 HOH   A O    1 
HETATM 2970 O O    . HOH   B 2 .   ? 48.33134 8.75264   21.28475 1.000 30.00261  ? 338 HOH   A O    1 
HETATM 2971 O O    . HOH   B 2 .   ? 41.58320 -18.38611 0.82250  1.000 45.59586  ? 339 HOH   A O    1 
HETATM 2972 O O    . HOH   B 2 .   ? 33.76444 -20.19664 18.19739 1.000 40.89154  ? 340 HOH   A O    1 
HETATM 2973 O O    . HOH   B 2 .   ? 42.34650 -24.78883 11.06870 1.000 20.69005  ? 341 HOH   A O    1 
HETATM 2974 O O    . HOH   B 2 .   ? 49.92907 9.77626   16.04929 1.000 35.20203  ? 342 HOH   A O    1 
HETATM 2975 O O    . HOH   B 2 .   ? 19.99987 -7.92656  19.36162 1.000 36.99832  ? 343 HOH   A O    1 
HETATM 2976 O O    . HOH   B 2 .   ? 53.60401 -10.64710 20.31015 1.000 65.44379  ? 344 HOH   A O    1 
HETATM 2977 O O    . HOH   B 2 .   ? 43.87475 -28.08073 17.21012 1.000 40.16183  ? 345 HOH   A O    1 
HETATM 2978 O O    . HOH   B 2 .   ? 25.73884 -20.48879 20.98958 1.000 63.04394  ? 346 HOH   A O    1 
HETATM 2979 O O    . HOH   B 2 .   ? 23.97749 0.30254   7.34983  1.000 47.57647  ? 347 HOH   A O    1 
HETATM 2980 O O    . HOH   B 2 .   ? 37.73983 -25.92055 16.07224 1.000 38.87871  ? 348 HOH   A O    1 
HETATM 2981 O O    . HOH   B 2 .   ? 38.37789 -20.39417 2.53617  1.000 33.55133  ? 349 HOH   A O    1 
HETATM 2982 O O    . HOH   B 2 .   ? 48.29624 -20.78475 22.97075 1.000 46.00658  ? 350 HOH   A O    1 
HETATM 2983 O O    . HOH   B 2 .   ? 42.004   12.389    11.418   1.000 28.78328  ? 351 HOH   A O    1 
HETATM 2984 O O    . HOH   B 2 .   ? 50.86583 -11.71268 7.07678  1.000 41.02824  ? 352 HOH   A O    1 
HETATM 2985 O O    . HOH   B 2 .   ? 54.52255 -15.33670 15.17477 1.000 41.40704  ? 353 HOH   A O    1 
HETATM 2986 O O    B HOH   B 2 .   ? 50.04561 -18.14158 21.72099 0.989 36.44690  ? 354 HOH   A O    1 
HETATM 2987 O O    . HOH   B 2 .   ? 18.89554 -9.81671  12.90393 1.000 38.10672  ? 355 HOH   A O    1 
HETATM 2988 O O    . HOH   B 2 .   ? 44.49372 -22.69690 22.74131 1.000 36.14488  ? 356 HOH   A O    1 
HETATM 2989 O O    . HOH   B 2 .   ? 37.62511 12.40442  23.43909 1.000 35.88911  ? 357 HOH   A O    1 
HETATM 2990 O O    . HOH   B 2 .   ? 47.83825 -0.51360  14.45082 1.000 38.94629  ? 358 HOH   A O    1 
HETATM 2991 O O    . HOH   B 2 .   ? 38.84539 -19.01501 0.38348  1.000 40.74941  ? 359 HOH   A O    1 
HETATM 2992 O O    . HOH   B 2 .   ? 38.23346 7.36566   2.62240  1.000 64.90026  ? 360 HOH   A O    1 
HETATM 2993 O O    . HOH   B 2 .   ? 21.18748 -9.91693  24.80570 1.000 37.48019  ? 361 HOH   A O    1 
HETATM 2994 O O    . HOH   B 2 .   ? 46.27306 1.93674   3.09947  1.000 51.13613  ? 362 HOH   A O    1 
HETATM 2995 O O    . HOH   B 2 .   ? 46.54271 -2.04535  8.29961  1.000 35.71835  ? 363 HOH   A O    1 
HETATM 2996 O O    . HOH   B 2 .   ? 23.19145 -6.29512  32.48101 1.000 48.68579  ? 364 HOH   A O    1 
HETATM 2997 O O    . HOH   B 2 .   ? 23.97020 -19.11720 4.80053  1.000 54.06388  ? 365 HOH   A O    1 
HETATM 2998 O O    . HOH   B 2 .   ? 24.80924 3.73250   12.25710 1.000 52.69087  ? 366 HOH   A O    1 
HETATM 2999 O O    . HOH   B 2 .   ? 22.25706 2.84937   18.68481 1.000 42.45362  ? 367 HOH   A O    1 
HETATM 3000 O O    . HOH   B 2 .   ? 51.32134 -11.41579 21.64000 1.000 43.82947  ? 368 HOH   A O    1 
HETATM 3001 O O    . HOH   B 2 .   ? 40.67035 -15.43221 1.16201  1.000 49.13808  ? 369 HOH   A O    1 
HETATM 3002 O O    . HOH   B 2 .   ? 28.78748 6.04151   12.10564 1.000 25.09580  ? 370 HOH   A O    1 
HETATM 3003 O O    . HOH   B 2 .   ? 42.91301 -25.97151 3.59941  1.000 38.27202  ? 371 HOH   A O    1 
HETATM 3004 O O    . HOH   B 2 .   ? 28.45260 -23.19010 11.03144 1.000 47.10441  ? 372 HOH   A O    1 
HETATM 3005 O O    . HOH   B 2 .   ? 50.54926 -4.10314  16.81464 1.000 40.98530  ? 373 HOH   A O    1 
HETATM 3006 O O    . HOH   B 2 .   ? 51.94995 -9.20443  23.30450 1.000 47.92771  ? 374 HOH   A O    1 
HETATM 3007 O O    . HOH   B 2 .   ? 34.18318 -19.48914 20.72716 1.000 48.07260  ? 375 HOH   A O    1 
HETATM 3008 O O    . HOH   B 2 .   ? 30.68293 -5.06648  -4.72739 1.000 61.93108  ? 376 HOH   A O    1 
HETATM 3009 O O    . HOH   B 2 .   ? 26.18154 -12.37610 27.83614 1.000 39.87215  ? 377 HOH   A O    1 
HETATM 3010 O O    . HOH   B 2 .   ? 48.30054 8.46196   3.91069  1.000 48.15118  ? 378 HOH   A O    1 
HETATM 3011 O O    . HOH   B 2 .   ? 36.69670 -19.25924 21.61471 1.000 54.73918  ? 379 HOH   A O    1 
HETATM 3012 O O    . HOH   B 2 .   ? 51.61888 -6.54995  15.54044 1.000 41.35003  ? 380 HOH   A O    1 
HETATM 3013 O O    . HOH   B 2 .   ? 48.20021 -2.49672  25.30101 1.000 43.00088  ? 381 HOH   A O    1 
HETATM 3014 O O    . HOH   B 2 .   ? 44.77389 -24.16959 3.95167  1.000 27.83320  ? 382 HOH   A O    1 
HETATM 3015 O O    . HOH   B 2 .   ? 38.95668 -13.54538 -2.72905 1.000 49.68993  ? 383 HOH   A O    1 
HETATM 3016 O O    . HOH   B 2 .   ? 22.64536 -12.43313 19.81974 1.000 42.55901  ? 384 HOH   A O    1 
HETATM 3017 O O    . HOH   B 2 .   ? 49.69518 10.82026  22.20386 1.000 57.34180  ? 385 HOH   A O    1 
HETATM 3018 O O    . HOH   B 2 .   ? 25.16729 -16.33801 24.50078 1.000 46.74530  ? 386 HOH   A O    1 
HETATM 3019 O O    B HOH   B 2 .   ? 48.67883 5.63040   3.28646  0.920 50.60653  ? 387 HOH   A O    1 
HETATM 3020 O O    . HOH   B 2 .   ? 26.72565 -15.12730 0.07537  1.000 50.61552  ? 388 HOH   A O    1 
HETATM 3021 O O    . HOH   B 2 .   ? 35.45763 7.63724   5.21478  1.000 49.51258  ? 389 HOH   A O    1 
HETATM 3022 O O    . HOH   B 2 .   ? 53.61425 -8.00747  17.63083 1.000 39.29957  ? 390 HOH   A O    1 
HETATM 3023 O O    . HOH   B 2 .   ? 28.79763 -8.64230  2.93648  1.000 41.70915  ? 391 HOH   A O    1 
HETATM 3024 O O    . HOH   B 2 .   ? 30.84062 -23.62437 6.21365  1.000 54.71753  ? 392 HOH   A O    1 
HETATM 3025 O O    . HOH   B 2 .   ? 25.416   -6.489    36.002   1.000 57.10076  ? 393 HOH   A O    1 
HETATM 3026 O O    . HOH   B 2 .   ? 38.734   11.544    8.253    1.000 40.55428  ? 394 HOH   A O    1 
HETATM 3027 O O    . HOH   B 2 .   ? 40.10178 12.70598  22.54701 1.000 37.84425  ? 395 HOH   A O    1 
HETATM 3028 O O    . HOH   B 2 .   ? 35.157   -14.193   26.957   1.000 21.80330  ? 396 HOH   A O    1 
HETATM 3029 O O    . HOH   B 2 .   ? 42.98420 -23.51959 25.60087 1.000 73.74081  ? 397 HOH   A O    1 
HETATM 3030 O O    . HOH   B 2 .   ? 40.86395 -28.38947 18.33732 1.000 58.10208  ? 398 HOH   A O    1 
HETATM 3031 O O    . HOH   B 2 .   ? 38.30386 -27.59836 17.99387 1.000 52.54569  ? 399 HOH   A O    1 
HETATM 3032 O O    A HOH   B 2 .   ? 48.40103 3.23647   4.06599  0.899 51.37780  ? 400 HOH   A O    1 
HETATM 3033 O O    . HOH   B 2 .   ? 55.98640 -11.91637 11.17591 1.000 62.28774  ? 401 HOH   A O    1 
HETATM 3034 O O    . HOH   B 2 .   ? 47.68743 -23.66899 23.29537 1.000 72.25292  ? 402 HOH   A O    1 
HETATM 3035 O O    . HOH   B 2 .   ? 26.34576 6.11903   12.27697 1.000 57.57211  ? 403 HOH   A O    1 
HETATM 3036 O O    . HOH   B 2 .   ? 38.67658 -20.59247 26.56660 1.000 51.69285  ? 404 HOH   A O    1 
HETATM 3037 O O    . HOH   B 2 .   ? 52.35048 8.22364   17.62326 1.000 73.85899  ? 405 HOH   A O    1 
HETATM 3038 O O    . HOH   B 2 .   ? 34.59746 -24.70394 14.02246 1.000 67.33956  ? 406 HOH   A O    1 
HETATM 3039 O O    . HOH   B 2 .   ? 50.44526 9.34504   18.97548 1.000 52.07780  ? 407 HOH   A O    1 
HETATM 3040 O O    . HOH   B 2 .   ? 12.20944 0.53394   12.71819 1.000 65.27470  ? 408 HOH   A O    1 
HETATM 3041 O O    . HOH   B 2 .   ? 51.51311 7.61043   14.50742 1.000 51.02754  ? 409 HOH   A O    1 
HETATM 3042 O O    . HOH   B 2 .   ? 34.519   -21.468   -2.415   1.000 73.87668  ? 410 HOH   A O    1 
HETATM 3043 O O    . HOH   B 2 .   ? 26.60395 -17.81479 0.71721  1.000 63.36068  ? 411 HOH   A O    1 
HETATM 3044 O O    . HOH   B 2 .   ? 56.36712 -9.92330  19.77162 1.000 81.66457  ? 412 HOH   A O    1 
HETATM 3045 O O    . HOH   B 2 .   ? 56.88239 -9.62830  22.69307 1.000 79.57374  ? 413 HOH   A O    1 
# 
