data_9CGD
# 
_entry.id   9CGD 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CGD         pdb_00009cgd 10.2210/pdb9cgd/pdb 
WWPDB D_1000285457 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CGD 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 9CEI unspecified 
PDB . 9CFI unspecified 
PDB . 9CFM unspecified 
PDB . 9CFO unspecified 
PDB . 9CFQ unspecified 
PDB . 9CGA unspecified 
PDB . 9CGB unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              mwilson13@unl.edu 
_pdbx_contact_author.name_first         Mark 
_pdbx_contact_author.name_last          Wilson 
_pdbx_contact_author.name_mi            A 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6317-900X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zielinski, K.'  1  ? 
'Dolamore, C.'   2  ? 
'Dalton, K.'     3  ? 
'Meisburger, S.' 4  ? 
'Smith, N.'      5  ? 
'Termini, J.'    6  ? 
'Henning, R.'    7  ? 
'Srajer, V.'     8  ? 
'Hekstra, D.'    9  ? 
'Pollack, L.'    10 ? 
'Wilson, M.A.'   11 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.07.19.604369 
_citation.pdbx_database_id_PubMed   39071394 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zielinski, K.A.' 1  ?                   
primary 'Dolamore, C.'    2  ?                   
primary 'Dalton, K.M.'    3  ?                   
primary 'Smith, N.'       4  ?                   
primary 'Termini, J.'     5  ?                   
primary 'Henning, R.'     6  ?                   
primary 'Srajer, V.'      7  ?                   
primary 'Hekstra, D.R.'   8  ?                   
primary 'Pollack, L.'     9  0000-0002-9366-4396 
primary 'Wilson, M.A.'    10 0000-0001-6317-900X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Parkinson disease protein 7' 20271.391 1   3.1.2.-,3.5.1.-,3.5.1.124 ? ? ? 
2 water   nat water                         18.015    124 ?                         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'Maillard deglycase,Oncogene DJ1,Parkinsonism-associated deglycase,Protein DJ-1,DJ-1,Protein/nucleic acid deglycase DJ-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;GSHMASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNL
GAQNLSESAAVKEILKEQENRKGLIAAI(A1A7V)AGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGL
ILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GSHMASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNL
GAQNLSESAAVKEILKEQENRKGLIAAIXAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRG
PGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY   n 
1 2   SER   n 
1 3   HIS   n 
1 4   MET   n 
1 5   ALA   n 
1 6   SER   n 
1 7   LYS   n 
1 8   ARG   n 
1 9   ALA   n 
1 10  LEU   n 
1 11  VAL   n 
1 12  ILE   n 
1 13  LEU   n 
1 14  ALA   n 
1 15  LYS   n 
1 16  GLY   n 
1 17  ALA   n 
1 18  GLU   n 
1 19  GLU   n 
1 20  MET   n 
1 21  GLU   n 
1 22  THR   n 
1 23  VAL   n 
1 24  ILE   n 
1 25  PRO   n 
1 26  VAL   n 
1 27  ASP   n 
1 28  VAL   n 
1 29  MET   n 
1 30  ARG   n 
1 31  ARG   n 
1 32  ALA   n 
1 33  GLY   n 
1 34  ILE   n 
1 35  LYS   n 
1 36  VAL   n 
1 37  THR   n 
1 38  VAL   n 
1 39  ALA   n 
1 40  GLY   n 
1 41  LEU   n 
1 42  ALA   n 
1 43  GLY   n 
1 44  LYS   n 
1 45  ASP   n 
1 46  PRO   n 
1 47  VAL   n 
1 48  GLN   n 
1 49  CYS   n 
1 50  SER   n 
1 51  ARG   n 
1 52  ASP   n 
1 53  VAL   n 
1 54  VAL   n 
1 55  ILE   n 
1 56  CYS   n 
1 57  PRO   n 
1 58  ASP   n 
1 59  ALA   n 
1 60  SER   n 
1 61  LEU   n 
1 62  GLU   n 
1 63  ASP   n 
1 64  ALA   n 
1 65  LYS   n 
1 66  LYS   n 
1 67  GLU   n 
1 68  GLY   n 
1 69  PRO   n 
1 70  TYR   n 
1 71  ASP   n 
1 72  VAL   n 
1 73  VAL   n 
1 74  VAL   n 
1 75  LEU   n 
1 76  PRO   n 
1 77  GLY   n 
1 78  GLY   n 
1 79  ASN   n 
1 80  LEU   n 
1 81  GLY   n 
1 82  ALA   n 
1 83  GLN   n 
1 84  ASN   n 
1 85  LEU   n 
1 86  SER   n 
1 87  GLU   n 
1 88  SER   n 
1 89  ALA   n 
1 90  ALA   n 
1 91  VAL   n 
1 92  LYS   n 
1 93  GLU   n 
1 94  ILE   n 
1 95  LEU   n 
1 96  LYS   n 
1 97  GLU   n 
1 98  GLN   n 
1 99  GLU   n 
1 100 ASN   n 
1 101 ARG   n 
1 102 LYS   n 
1 103 GLY   n 
1 104 LEU   n 
1 105 ILE   n 
1 106 ALA   n 
1 107 ALA   n 
1 108 ILE   n 
1 109 A1A7V n 
1 110 ALA   n 
1 111 GLY   n 
1 112 PRO   n 
1 113 THR   n 
1 114 ALA   n 
1 115 LEU   n 
1 116 LEU   n 
1 117 ALA   n 
1 118 HIS   n 
1 119 GLU   n 
1 120 ILE   n 
1 121 GLY   n 
1 122 PHE   n 
1 123 GLY   n 
1 124 SER   n 
1 125 LYS   n 
1 126 VAL   n 
1 127 THR   n 
1 128 THR   n 
1 129 HIS   n 
1 130 PRO   n 
1 131 LEU   n 
1 132 ALA   n 
1 133 LYS   n 
1 134 ASP   n 
1 135 LYS   n 
1 136 MET   n 
1 137 MET   n 
1 138 ASN   n 
1 139 GLY   n 
1 140 GLY   n 
1 141 HIS   n 
1 142 TYR   n 
1 143 THR   n 
1 144 TYR   n 
1 145 SER   n 
1 146 GLU   n 
1 147 ASN   n 
1 148 ARG   n 
1 149 VAL   n 
1 150 GLU   n 
1 151 LYS   n 
1 152 ASP   n 
1 153 GLY   n 
1 154 LEU   n 
1 155 ILE   n 
1 156 LEU   n 
1 157 THR   n 
1 158 SER   n 
1 159 ARG   n 
1 160 GLY   n 
1 161 PRO   n 
1 162 GLY   n 
1 163 THR   n 
1 164 SER   n 
1 165 PHE   n 
1 166 GLU   n 
1 167 PHE   n 
1 168 ALA   n 
1 169 LEU   n 
1 170 ALA   n 
1 171 ILE   n 
1 172 VAL   n 
1 173 GLU   n 
1 174 ALA   n 
1 175 LEU   n 
1 176 ASN   n 
1 177 GLY   n 
1 178 LYS   n 
1 179 GLU   n 
1 180 VAL   n 
1 181 ALA   n 
1 182 ALA   n 
1 183 GLN   n 
1 184 VAL   n 
1 185 LYS   n 
1 186 ALA   n 
1 187 PRO   n 
1 188 LEU   n 
1 189 VAL   n 
1 190 LEU   n 
1 191 LYS   n 
1 192 ASP   n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   192 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PARK7 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pET15b 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1A7V 'L-peptide linking' n S-lactoyl-L-cysteine 'S-[(2S)-2-hydroxypropanoyl]-L-cysteine' 'C6 H11 N O4 S'  193.221 
ALA   'L-peptide linking' y ALANINE              ?                                        'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE             ?                                        'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE           ?                                        'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'      ?                                        'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE             ?                                        'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE            ?                                        'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'      ?                                        'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE              ?                                        'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE            ?                                        'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                ?                                        'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE           ?                                        'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE              ?                                        'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE               ?                                        'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE           ?                                        'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE        ?                                        'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE              ?                                        'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE               ?                                        'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE            ?                                        'C4 H9 N O3'     119.119 
TYR   'L-peptide linking' y TYROSINE             ?                                        'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE               ?                                        'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY   1   -2  ?   ?     ?   A . n 
A 1 2   SER   2   -1  ?   ?     ?   A . n 
A 1 3   HIS   3   0   ?   ?     ?   A . n 
A 1 4   MET   4   1   ?   ?     ?   A . n 
A 1 5   ALA   5   2   2   ALA   ALA A . n 
A 1 6   SER   6   3   3   SER   SER A . n 
A 1 7   LYS   7   4   4   LYS   LYS A . n 
A 1 8   ARG   8   5   5   ARG   ARG A . n 
A 1 9   ALA   9   6   6   ALA   ALA A . n 
A 1 10  LEU   10  7   7   LEU   LEU A . n 
A 1 11  VAL   11  8   8   VAL   VAL A . n 
A 1 12  ILE   12  9   9   ILE   ILE A . n 
A 1 13  LEU   13  10  10  LEU   LEU A . n 
A 1 14  ALA   14  11  11  ALA   ALA A . n 
A 1 15  LYS   15  12  12  LYS   LYS A . n 
A 1 16  GLY   16  13  13  GLY   GLY A . n 
A 1 17  ALA   17  14  14  ALA   ALA A . n 
A 1 18  GLU   18  15  15  GLU   GLU A . n 
A 1 19  GLU   19  16  16  GLU   GLU A . n 
A 1 20  MET   20  17  17  MET   MET A . n 
A 1 21  GLU   21  18  18  GLU   GLU A . n 
A 1 22  THR   22  19  19  THR   THR A . n 
A 1 23  VAL   23  20  20  VAL   VAL A . n 
A 1 24  ILE   24  21  21  ILE   ILE A . n 
A 1 25  PRO   25  22  22  PRO   PRO A . n 
A 1 26  VAL   26  23  23  VAL   VAL A . n 
A 1 27  ASP   27  24  24  ASP   ASP A . n 
A 1 28  VAL   28  25  25  VAL   VAL A . n 
A 1 29  MET   29  26  26  MET   MET A . n 
A 1 30  ARG   30  27  27  ARG   ARG A . n 
A 1 31  ARG   31  28  28  ARG   ARG A . n 
A 1 32  ALA   32  29  29  ALA   ALA A . n 
A 1 33  GLY   33  30  30  GLY   GLY A . n 
A 1 34  ILE   34  31  31  ILE   ILE A . n 
A 1 35  LYS   35  32  32  LYS   LYS A . n 
A 1 36  VAL   36  33  33  VAL   VAL A . n 
A 1 37  THR   37  34  34  THR   THR A . n 
A 1 38  VAL   38  35  35  VAL   VAL A . n 
A 1 39  ALA   39  36  36  ALA   ALA A . n 
A 1 40  GLY   40  37  37  GLY   GLY A . n 
A 1 41  LEU   41  38  38  LEU   LEU A . n 
A 1 42  ALA   42  39  39  ALA   ALA A . n 
A 1 43  GLY   43  40  40  GLY   GLY A . n 
A 1 44  LYS   44  41  41  LYS   LYS A . n 
A 1 45  ASP   45  42  42  ASP   ASP A . n 
A 1 46  PRO   46  43  43  PRO   PRO A . n 
A 1 47  VAL   47  44  44  VAL   VAL A . n 
A 1 48  GLN   48  45  45  GLN   GLN A . n 
A 1 49  CYS   49  46  46  CYS   CYS A . n 
A 1 50  SER   50  47  47  SER   SER A . n 
A 1 51  ARG   51  48  48  ARG   ARG A . n 
A 1 52  ASP   52  49  49  ASP   ASP A . n 
A 1 53  VAL   53  50  50  VAL   VAL A . n 
A 1 54  VAL   54  51  51  VAL   VAL A . n 
A 1 55  ILE   55  52  52  ILE   ILE A . n 
A 1 56  CYS   56  53  53  CYS   CYS A . n 
A 1 57  PRO   57  54  54  PRO   PRO A . n 
A 1 58  ASP   58  55  55  ASP   ASP A . n 
A 1 59  ALA   59  56  56  ALA   ALA A . n 
A 1 60  SER   60  57  57  SER   SER A . n 
A 1 61  LEU   61  58  58  LEU   LEU A . n 
A 1 62  GLU   62  59  59  GLU   GLU A . n 
A 1 63  ASP   63  60  60  ASP   ASP A . n 
A 1 64  ALA   64  61  61  ALA   ALA A . n 
A 1 65  LYS   65  62  62  LYS   LYS A . n 
A 1 66  LYS   66  63  63  LYS   LYS A . n 
A 1 67  GLU   67  64  64  GLU   GLU A . n 
A 1 68  GLY   68  65  65  GLY   GLY A . n 
A 1 69  PRO   69  66  66  PRO   PRO A . n 
A 1 70  TYR   70  67  67  TYR   TYR A . n 
A 1 71  ASP   71  68  68  ASP   ASP A . n 
A 1 72  VAL   72  69  69  VAL   VAL A . n 
A 1 73  VAL   73  70  70  VAL   VAL A . n 
A 1 74  VAL   74  71  71  VAL   VAL A . n 
A 1 75  LEU   75  72  72  LEU   LEU A . n 
A 1 76  PRO   76  73  73  PRO   PRO A . n 
A 1 77  GLY   77  74  74  GLY   GLY A . n 
A 1 78  GLY   78  75  75  GLY   GLY A . n 
A 1 79  ASN   79  76  76  ASN   ASN A . n 
A 1 80  LEU   80  77  77  LEU   LEU A . n 
A 1 81  GLY   81  78  78  GLY   GLY A . n 
A 1 82  ALA   82  79  79  ALA   ALA A . n 
A 1 83  GLN   83  80  80  GLN   GLN A . n 
A 1 84  ASN   84  81  81  ASN   ASN A . n 
A 1 85  LEU   85  82  82  LEU   LEU A . n 
A 1 86  SER   86  83  83  SER   SER A . n 
A 1 87  GLU   87  84  84  GLU   GLU A . n 
A 1 88  SER   88  85  85  SER   SER A . n 
A 1 89  ALA   89  86  86  ALA   ALA A . n 
A 1 90  ALA   90  87  87  ALA   ALA A . n 
A 1 91  VAL   91  88  88  VAL   VAL A . n 
A 1 92  LYS   92  89  89  LYS   LYS A . n 
A 1 93  GLU   93  90  90  GLU   GLU A . n 
A 1 94  ILE   94  91  91  ILE   ILE A . n 
A 1 95  LEU   95  92  92  LEU   LEU A . n 
A 1 96  LYS   96  93  93  LYS   LYS A . n 
A 1 97  GLU   97  94  94  GLU   GLU A . n 
A 1 98  GLN   98  95  95  GLN   GLN A . n 
A 1 99  GLU   99  96  96  GLU   GLU A . n 
A 1 100 ASN   100 97  97  ASN   ASN A . n 
A 1 101 ARG   101 98  98  ARG   ARG A . n 
A 1 102 LYS   102 99  99  LYS   LYS A . n 
A 1 103 GLY   103 100 100 GLY   GLY A . n 
A 1 104 LEU   104 101 101 LEU   LEU A . n 
A 1 105 ILE   105 102 102 ILE   ILE A . n 
A 1 106 ALA   106 103 103 ALA   ALA A . n 
A 1 107 ALA   107 104 104 ALA   ALA A . n 
A 1 108 ILE   108 105 105 ILE   ILE A . n 
A 1 109 A1A7V 109 106 106 A1A7V CYS A . n 
A 1 110 ALA   110 107 107 ALA   ALA A . n 
A 1 111 GLY   111 108 108 GLY   GLY A . n 
A 1 112 PRO   112 109 109 PRO   PRO A . n 
A 1 113 THR   113 110 110 THR   THR A . n 
A 1 114 ALA   114 111 111 ALA   ALA A . n 
A 1 115 LEU   115 112 112 LEU   LEU A . n 
A 1 116 LEU   116 113 113 LEU   LEU A . n 
A 1 117 ALA   117 114 114 ALA   ALA A . n 
A 1 118 HIS   118 115 115 HIS   HIS A . n 
A 1 119 GLU   119 116 116 GLU   GLU A . n 
A 1 120 ILE   120 117 117 ILE   ILE A . n 
A 1 121 GLY   121 118 118 GLY   GLY A . n 
A 1 122 PHE   122 119 119 PHE   PHE A . n 
A 1 123 GLY   123 120 120 GLY   GLY A . n 
A 1 124 SER   124 121 121 SER   SER A . n 
A 1 125 LYS   125 122 122 LYS   LYS A . n 
A 1 126 VAL   126 123 123 VAL   VAL A . n 
A 1 127 THR   127 124 124 THR   THR A . n 
A 1 128 THR   128 125 125 THR   THR A . n 
A 1 129 HIS   129 126 126 HIS   HIS A . n 
A 1 130 PRO   130 127 127 PRO   PRO A . n 
A 1 131 LEU   131 128 128 LEU   LEU A . n 
A 1 132 ALA   132 129 129 ALA   ALA A . n 
A 1 133 LYS   133 130 130 LYS   LYS A . n 
A 1 134 ASP   134 131 131 ASP   ASP A . n 
A 1 135 LYS   135 132 132 LYS   LYS A . n 
A 1 136 MET   136 133 133 MET   MET A . n 
A 1 137 MET   137 134 134 MET   MET A . n 
A 1 138 ASN   138 135 135 ASN   ASN A . n 
A 1 139 GLY   139 136 136 GLY   GLY A . n 
A 1 140 GLY   140 137 137 GLY   GLY A . n 
A 1 141 HIS   141 138 138 HIS   HIS A . n 
A 1 142 TYR   142 139 139 TYR   TYR A . n 
A 1 143 THR   143 140 140 THR   THR A . n 
A 1 144 TYR   144 141 141 TYR   TYR A . n 
A 1 145 SER   145 142 142 SER   SER A . n 
A 1 146 GLU   146 143 143 GLU   GLU A . n 
A 1 147 ASN   147 144 144 ASN   ASN A . n 
A 1 148 ARG   148 145 145 ARG   ARG A . n 
A 1 149 VAL   149 146 146 VAL   VAL A . n 
A 1 150 GLU   150 147 147 GLU   GLU A . n 
A 1 151 LYS   151 148 148 LYS   LYS A . n 
A 1 152 ASP   152 149 149 ASP   ASP A . n 
A 1 153 GLY   153 150 150 GLY   GLY A . n 
A 1 154 LEU   154 151 151 LEU   LEU A . n 
A 1 155 ILE   155 152 152 ILE   ILE A . n 
A 1 156 LEU   156 153 153 LEU   LEU A . n 
A 1 157 THR   157 154 154 THR   THR A . n 
A 1 158 SER   158 155 155 SER   SER A . n 
A 1 159 ARG   159 156 156 ARG   ARG A . n 
A 1 160 GLY   160 157 157 GLY   GLY A . n 
A 1 161 PRO   161 158 158 PRO   PRO A . n 
A 1 162 GLY   162 159 159 GLY   GLY A . n 
A 1 163 THR   163 160 160 THR   THR A . n 
A 1 164 SER   164 161 161 SER   SER A . n 
A 1 165 PHE   165 162 162 PHE   PHE A . n 
A 1 166 GLU   166 163 163 GLU   GLU A . n 
A 1 167 PHE   167 164 164 PHE   PHE A . n 
A 1 168 ALA   168 165 165 ALA   ALA A . n 
A 1 169 LEU   169 166 166 LEU   LEU A . n 
A 1 170 ALA   170 167 167 ALA   ALA A . n 
A 1 171 ILE   171 168 168 ILE   ILE A . n 
A 1 172 VAL   172 169 169 VAL   VAL A . n 
A 1 173 GLU   173 170 170 GLU   GLU A . n 
A 1 174 ALA   174 171 171 ALA   ALA A . n 
A 1 175 LEU   175 172 172 LEU   LEU A . n 
A 1 176 ASN   176 173 173 ASN   ASN A . n 
A 1 177 GLY   177 174 174 GLY   GLY A . n 
A 1 178 LYS   178 175 175 LYS   LYS A . n 
A 1 179 GLU   179 176 176 GLU   GLU A . n 
A 1 180 VAL   180 177 177 VAL   VAL A . n 
A 1 181 ALA   181 178 178 ALA   ALA A . n 
A 1 182 ALA   182 179 179 ALA   ALA A . n 
A 1 183 GLN   183 180 180 GLN   GLN A . n 
A 1 184 VAL   184 181 181 VAL   VAL A . n 
A 1 185 LYS   185 182 182 LYS   LYS A . n 
A 1 186 ALA   186 183 183 ALA   ALA A . n 
A 1 187 PRO   187 184 184 PRO   PRO A . n 
A 1 188 LEU   188 185 185 LEU   LEU A . n 
A 1 189 VAL   189 186 186 VAL   VAL A . n 
A 1 190 LEU   190 187 187 LEU   LEU A . n 
A 1 191 LYS   191 188 188 LYS   LYS A . n 
A 1 192 ASP   192 189 189 ASP   ASP A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1A7V 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1A7V 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 HOH 1   301 27  HOH HOH A . 
B 2 HOH 2   302 4   HOH HOH A . 
B 2 HOH 3   303 97  HOH HOH A . 
B 2 HOH 4   304 54  HOH HOH A . 
B 2 HOH 5   305 74  HOH HOH A . 
B 2 HOH 6   306 68  HOH HOH A . 
B 2 HOH 7   307 23  HOH HOH A . 
B 2 HOH 8   308 37  HOH HOH A . 
B 2 HOH 9   309 6   HOH HOH A . 
B 2 HOH 10  310 118 HOH HOH A . 
B 2 HOH 11  311 30  HOH HOH A . 
B 2 HOH 12  312 25  HOH HOH A . 
B 2 HOH 13  313 9   HOH HOH A . 
B 2 HOH 14  314 5   HOH HOH A . 
B 2 HOH 15  315 36  HOH HOH A . 
B 2 HOH 16  316 87  HOH HOH A . 
B 2 HOH 17  317 59  HOH HOH A . 
B 2 HOH 18  318 21  HOH HOH A . 
B 2 HOH 19  319 7   HOH HOH A . 
B 2 HOH 20  320 8   HOH HOH A . 
B 2 HOH 21  321 1   HOH HOH A . 
B 2 HOH 22  322 45  HOH HOH A . 
B 2 HOH 23  323 11  HOH HOH A . 
B 2 HOH 24  324 26  HOH HOH A . 
B 2 HOH 25  325 31  HOH HOH A . 
B 2 HOH 26  326 66  HOH HOH A . 
B 2 HOH 27  327 125 HOH HOH A . 
B 2 HOH 28  328 105 HOH HOH A . 
B 2 HOH 29  329 55  HOH HOH A . 
B 2 HOH 30  330 3   HOH HOH A . 
B 2 HOH 31  331 57  HOH HOH A . 
B 2 HOH 32  332 15  HOH HOH A . 
B 2 HOH 33  333 115 HOH HOH A . 
B 2 HOH 34  334 38  HOH HOH A . 
B 2 HOH 35  335 56  HOH HOH A . 
B 2 HOH 36  336 28  HOH HOH A . 
B 2 HOH 37  337 19  HOH HOH A . 
B 2 HOH 38  338 47  HOH HOH A . 
B 2 HOH 39  339 76  HOH HOH A . 
B 2 HOH 40  340 117 HOH HOH A . 
B 2 HOH 41  341 91  HOH HOH A . 
B 2 HOH 42  342 14  HOH HOH A . 
B 2 HOH 43  343 63  HOH HOH A . 
B 2 HOH 44  344 10  HOH HOH A . 
B 2 HOH 45  345 42  HOH HOH A . 
B 2 HOH 46  346 120 HOH HOH A . 
B 2 HOH 47  347 41  HOH HOH A . 
B 2 HOH 48  348 34  HOH HOH A . 
B 2 HOH 49  349 123 HOH HOH A . 
B 2 HOH 50  350 32  HOH HOH A . 
B 2 HOH 51  351 94  HOH HOH A . 
B 2 HOH 52  352 51  HOH HOH A . 
B 2 HOH 53  353 17  HOH HOH A . 
B 2 HOH 54  354 24  HOH HOH A . 
B 2 HOH 55  355 101 HOH HOH A . 
B 2 HOH 56  356 85  HOH HOH A . 
B 2 HOH 57  357 22  HOH HOH A . 
B 2 HOH 58  358 16  HOH HOH A . 
B 2 HOH 59  359 86  HOH HOH A . 
B 2 HOH 60  360 126 HOH HOH A . 
B 2 HOH 61  361 84  HOH HOH A . 
B 2 HOH 62  362 93  HOH HOH A . 
B 2 HOH 63  363 104 HOH HOH A . 
B 2 HOH 64  364 77  HOH HOH A . 
B 2 HOH 65  365 121 HOH HOH A . 
B 2 HOH 66  366 69  HOH HOH A . 
B 2 HOH 67  367 89  HOH HOH A . 
B 2 HOH 68  368 13  HOH HOH A . 
B 2 HOH 69  369 2   HOH HOH A . 
B 2 HOH 70  370 83  HOH HOH A . 
B 2 HOH 71  371 12  HOH HOH A . 
B 2 HOH 72  372 62  HOH HOH A . 
B 2 HOH 73  373 80  HOH HOH A . 
B 2 HOH 74  374 43  HOH HOH A . 
B 2 HOH 75  375 46  HOH HOH A . 
B 2 HOH 76  376 88  HOH HOH A . 
B 2 HOH 77  377 70  HOH HOH A . 
B 2 HOH 78  378 58  HOH HOH A . 
B 2 HOH 79  379 60  HOH HOH A . 
B 2 HOH 80  380 116 HOH HOH A . 
B 2 HOH 81  381 35  HOH HOH A . 
B 2 HOH 82  382 92  HOH HOH A . 
B 2 HOH 83  383 53  HOH HOH A . 
B 2 HOH 84  384 90  HOH HOH A . 
B 2 HOH 85  385 20  HOH HOH A . 
B 2 HOH 86  386 113 HOH HOH A . 
B 2 HOH 87  387 40  HOH HOH A . 
B 2 HOH 88  388 64  HOH HOH A . 
B 2 HOH 89  389 72  HOH HOH A . 
B 2 HOH 90  390 71  HOH HOH A . 
B 2 HOH 91  391 52  HOH HOH A . 
B 2 HOH 92  392 33  HOH HOH A . 
B 2 HOH 93  393 65  HOH HOH A . 
B 2 HOH 94  394 112 HOH HOH A . 
B 2 HOH 95  395 82  HOH HOH A . 
B 2 HOH 96  396 78  HOH HOH A . 
B 2 HOH 97  397 39  HOH HOH A . 
B 2 HOH 98  398 18  HOH HOH A . 
B 2 HOH 99  399 100 HOH HOH A . 
B 2 HOH 100 400 49  HOH HOH A . 
B 2 HOH 101 401 96  HOH HOH A . 
B 2 HOH 102 402 106 HOH HOH A . 
B 2 HOH 103 403 122 HOH HOH A . 
B 2 HOH 104 404 102 HOH HOH A . 
B 2 HOH 105 405 73  HOH HOH A . 
B 2 HOH 106 406 119 HOH HOH A . 
B 2 HOH 107 407 109 HOH HOH A . 
B 2 HOH 108 408 61  HOH HOH A . 
B 2 HOH 109 409 111 HOH HOH A . 
B 2 HOH 110 410 75  HOH HOH A . 
B 2 HOH 111 411 48  HOH HOH A . 
B 2 HOH 112 412 81  HOH HOH A . 
B 2 HOH 113 413 98  HOH HOH A . 
B 2 HOH 114 414 50  HOH HOH A . 
B 2 HOH 115 415 103 HOH HOH A . 
B 2 HOH 116 416 44  HOH HOH A . 
B 2 HOH 117 417 110 HOH HOH A . 
B 2 HOH 118 418 124 HOH HOH A . 
B 2 HOH 119 419 107 HOH HOH A . 
B 2 HOH 120 420 99  HOH HOH A . 
B 2 HOH 121 421 79  HOH HOH A . 
B 2 HOH 122 422 114 HOH HOH A . 
B 2 HOH 123 423 95  HOH HOH A . 
B 2 HOH 124 424 108 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX       ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? Precognition ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL     ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX       ? ? ? 1.19.2_4158 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CGD 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     76.030 
_cell.length_a_esd                 ? 
_cell.length_b                     76.030 
_cell.length_b_esd                 ? 
_cell.length_c                     76.140 
_cell.length_c_esd                 ? 
_cell.volume                       381165.412 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CGD 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                152 
_symmetry.space_group_name_Hall            
;P 31 2"
;
_symmetry.space_group_name_H-M             'P 31 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CGD 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.15 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          60.89 
_exptl_crystal.description                  '20-25 micron microcrystals' 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'RAYONIX MX340-HS' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-11-13 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   L 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             LAUE 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
loop_
_diffrn_radiation_wavelength.id 
_diffrn_radiation_wavelength.wavelength 
_diffrn_radiation_wavelength.wt 
1 1.240 1.0 
2 1.016 1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 14-ID-B' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.240-1.016 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   14-ID-B 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          27.55 
_reflns.entry_id                                       9CGD 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.77 
_reflns.d_resolution_low                               65.84 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     24998 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.01 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                95.32 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4.68 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   0.1010 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.77 
_reflns_shell.d_res_low                                     1.80 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.31 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2428 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               90.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.05 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.70 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               34.46 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CGD 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.97 
_refine.ls_d_res_low                             32.96 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     18236 
_refine.ls_number_reflns_R_free                  902 
_refine.ls_number_reflns_R_work                  17334 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.06 
_refine.ls_percent_reflns_R_free                 4.95 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1500 
_refine.ls_R_factor_R_free                       0.1772 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1485 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'FOURIER SYNTHESIS' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 20.9654 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1935 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.97 
_refine_hist.d_res_low                        32.96 
_refine_hist.number_atoms_solvent             124 
_refine_hist.number_atoms_total               1512 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1383 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         5 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0059  ? 1466 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7415  ? 1986 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0488  ? 234  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0060  ? 261  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.4792 ? 567  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.97 2.09  . . 147 2837 98.97 . . . . 0.2656 . . . . . . . . . . . 0.2841 
'X-RAY DIFFRACTION' 2.09 2.25  . . 142 2853 99.21 . . . . 0.2108 . . . . . . . . . . . 0.2865 
'X-RAY DIFFRACTION' 2.26 2.48  . . 166 2832 99.17 . . . . 0.1788 . . . . . . . . . . . 0.2076 
'X-RAY DIFFRACTION' 2.48 2.84  . . 146 2890 99.02 . . . . 0.1542 . . . . . . . . . . . 0.1720 
'X-RAY DIFFRACTION' 2.84 3.58  . . 137 2912 99.09 . . . . 0.1375 . . . . . . . . . . . 0.1843 
'X-RAY DIFFRACTION' 3.58 32.96 . . 164 3010 98.94 . . . . 0.1090 . . . . . . . . . . . 0.1285 
# 
_struct.entry_id                     9CGD 
_struct.title                        
'Human DJ-1, 10 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CGD 
_struct_keywords.text            
'Glutathione-independent glyoxalase, mix-and-inject serial crystallography, Laue diffraction, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PARK7_HUMAN 
_struct_ref.pdbx_db_accession          Q99497 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQ
NLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGT
SFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9CGD 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 4 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 192 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q99497 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  189 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       189 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CGD GLY A 1 ? UNP Q99497 ? ? 'expression tag' -2 1 
1 9CGD SER A 2 ? UNP Q99497 ? ? 'expression tag' -1 2 
1 9CGD HIS A 3 ? UNP Q99497 ? ? 'expression tag' 0  3 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 2830  ? 
1 MORE         -17   ? 
1 'SSA (A^2)'  15050 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z         1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000  
2 'crystal symmetry operation' 5_555 x-y,-y,-z+2/3 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 50.7600000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 18  ? ALA A 32  ? GLU A 15  ALA A 29  1 ? 15 
HELX_P HELX_P2  AA2 LEU A 61  ? GLU A 67  ? LEU A 58  GLU A 64  1 ? 7  
HELX_P HELX_P3  AA3 GLY A 78  ? SER A 88  ? GLY A 75  SER A 85  1 ? 11 
HELX_P HELX_P4  AA4 SER A 88  ? ARG A 101 ? SER A 85  ARG A 98  1 ? 14 
HELX_P HELX_P5  AA5 PRO A 112 ? HIS A 118 ? PRO A 109 HIS A 115 1 ? 7  
HELX_P HELX_P6  AA6 HIS A 129 ? LEU A 131 ? HIS A 126 LEU A 128 5 ? 3  
HELX_P HELX_P7  AA7 ALA A 132 ? MET A 137 ? ALA A 129 MET A 134 1 ? 6  
HELX_P HELX_P8  AA8 GLY A 160 ? GLY A 162 ? GLY A 157 GLY A 159 5 ? 3  
HELX_P HELX_P9  AA9 THR A 163 ? GLY A 177 ? THR A 160 GLY A 174 1 ? 15 
HELX_P HELX_P10 AB1 GLY A 177 ? ALA A 186 ? GLY A 174 ALA A 183 1 ? 10 
HELX_P HELX_P11 AB2 PRO A 187 ? VAL A 189 ? PRO A 184 VAL A 186 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A ILE   108 C ? ? ? 1_555 A A1A7V 109 N ? ? A ILE   105 A A1A7V 106 1_555 ? ? ? ? ? ? ? 1.340 ? ? 
covale2 covale both ? A A1A7V 109 C ? ? ? 1_555 A ALA   110 N ? ? A A1A7V 106 A ALA   107 1_555 ? ? ? ? ? ? ? 1.337 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      A1A7V 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       109 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     . 
_pdbx_modification_feature.modified_residue_label_asym_id     . 
_pdbx_modification_feature.modified_residue_label_seq_id      . 
_pdbx_modification_feature.modified_residue_label_alt_id      . 
_pdbx_modification_feature.auth_comp_id                       A1A7V 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        106 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      . 
_pdbx_modification_feature.modified_residue_auth_asym_id      . 
_pdbx_modification_feature.modified_residue_auth_seq_id       . 
_pdbx_modification_feature.modified_residue_PDB_ins_code      . 
_pdbx_modification_feature.modified_residue_symmetry          . 
_pdbx_modification_feature.comp_id_linking_atom               . 
_pdbx_modification_feature.modified_residue_id_linking_atom   . 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        A1A7V 
_pdbx_modification_feature.type                               Lactoylation 
_pdbx_modification_feature.category                           'Named protein modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLY 
_struct_mon_prot_cis.label_seq_id           68 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLY 
_struct_mon_prot_cis.auth_seq_id            65 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    69 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     66 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -3.53 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 59  ? SER A 60  ? ALA A 56  SER A 57  
AA1 2 LYS A 35  ? GLY A 40  ? LYS A 32  GLY A 37  
AA1 3 ARG A 8   ? LEU A 13  ? ARG A 5   LEU A 10  
AA1 4 VAL A 72  ? LEU A 75  ? VAL A 69  LEU A 72  
AA1 5 LEU A 104 ? ILE A 108 ? LEU A 101 ILE A 105 
AA1 6 ILE A 155 ? SER A 158 ? ILE A 152 SER A 155 
AA1 7 VAL A 149 ? ASP A 152 ? VAL A 146 ASP A 149 
AA2 1 VAL A 47  ? GLN A 48  ? VAL A 44  GLN A 45  
AA2 2 VAL A 54  ? ILE A 55  ? VAL A 51  ILE A 52  
AA3 1 LYS A 125 ? VAL A 126 ? LYS A 122 VAL A 123 
AA3 2 THR A 143 ? TYR A 144 ? THR A 140 TYR A 141 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 59  ? O ALA A 56  N GLY A 40  ? N GLY A 37  
AA1 2 3 O ALA A 39  ? O ALA A 36  N LEU A 13  ? N LEU A 10  
AA1 3 4 N LEU A 10  ? N LEU A 7   O VAL A 74  ? O VAL A 71  
AA1 4 5 N LEU A 75  ? N LEU A 72  O ALA A 106 ? O ALA A 103 
AA1 5 6 N ILE A 105 ? N ILE A 102 O LEU A 156 ? O LEU A 153 
AA1 6 7 O THR A 157 ? O THR A 154 N GLU A 150 ? N GLU A 147 
AA2 1 2 N VAL A 47  ? N VAL A 44  O ILE A 55  ? O ILE A 52  
AA3 1 2 N VAL A 126 ? N VAL A 123 O THR A 143 ? O THR A 140 
# 
_pdbx_entry_details.entry_id                   9CGD 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    A1A7V 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     106 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             73.42 
_pdbx_validate_torsion.psi             -107.03 
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    A 
_pdbx_struct_mod_residue.label_comp_id    A1A7V 
_pdbx_struct_mod_residue.label_seq_id     109 
_pdbx_struct_mod_residue.auth_asym_id     A 
_pdbx_struct_mod_residue.auth_comp_id     A1A7V 
_pdbx_struct_mod_residue.auth_seq_id      106 
_pdbx_struct_mod_residue.PDB_ins_code     ? 
_pdbx_struct_mod_residue.parent_comp_id   CYS 
_pdbx_struct_mod_residue.details          'modified residue' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+1/3   
3 -x+y,-x,z+2/3  
4 x-y,-y,-z+2/3  
5 -x,-x+y,-z+1/3 
6 y,x,-z         
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY -2 ? A GLY 1 
2 1 Y 1 A SER -1 ? A SER 2 
3 1 Y 1 A HIS 0  ? A HIS 3 
4 1 Y 1 A MET 1  ? A MET 4 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1A7V C    C N N 1   
A1A7V N    N N N 2   
A1A7V O    O N N 3   
A1A7V CA   C N R 4   
A1A7V CB   C N N 5   
A1A7V SG   S N N 6   
A1A7V C1   C N N 7   
A1A7V O1   O N N 8   
A1A7V C2   C N S 9   
A1A7V O2   O N N 10  
A1A7V C3   C N N 11  
A1A7V H    H N N 12  
A1A7V H2   H N N 13  
A1A7V HA   H N N 14  
A1A7V HB3  H N N 15  
A1A7V HB2  H N N 16  
A1A7V H20  H N N 17  
A1A7V HO2  H N N 18  
A1A7V H3B  H N N 19  
A1A7V H3A  H N N 20  
A1A7V H3   H N N 21  
A1A7V OXT  O N N 22  
A1A7V HXT  H N N 23  
ALA   N    N N N 24  
ALA   CA   C N S 25  
ALA   C    C N N 26  
ALA   O    O N N 27  
ALA   CB   C N N 28  
ALA   OXT  O N N 29  
ALA   H    H N N 30  
ALA   H2   H N N 31  
ALA   HA   H N N 32  
ALA   HB1  H N N 33  
ALA   HB2  H N N 34  
ALA   HB3  H N N 35  
ALA   HXT  H N N 36  
ARG   N    N N N 37  
ARG   CA   C N S 38  
ARG   C    C N N 39  
ARG   O    O N N 40  
ARG   CB   C N N 41  
ARG   CG   C N N 42  
ARG   CD   C N N 43  
ARG   NE   N N N 44  
ARG   CZ   C N N 45  
ARG   NH1  N N N 46  
ARG   NH2  N N N 47  
ARG   OXT  O N N 48  
ARG   H    H N N 49  
ARG   H2   H N N 50  
ARG   HA   H N N 51  
ARG   HB2  H N N 52  
ARG   HB3  H N N 53  
ARG   HG2  H N N 54  
ARG   HG3  H N N 55  
ARG   HD2  H N N 56  
ARG   HD3  H N N 57  
ARG   HE   H N N 58  
ARG   HH11 H N N 59  
ARG   HH12 H N N 60  
ARG   HH21 H N N 61  
ARG   HH22 H N N 62  
ARG   HXT  H N N 63  
ASN   N    N N N 64  
ASN   CA   C N S 65  
ASN   C    C N N 66  
ASN   O    O N N 67  
ASN   CB   C N N 68  
ASN   CG   C N N 69  
ASN   OD1  O N N 70  
ASN   ND2  N N N 71  
ASN   OXT  O N N 72  
ASN   H    H N N 73  
ASN   H2   H N N 74  
ASN   HA   H N N 75  
ASN   HB2  H N N 76  
ASN   HB3  H N N 77  
ASN   HD21 H N N 78  
ASN   HD22 H N N 79  
ASN   HXT  H N N 80  
ASP   N    N N N 81  
ASP   CA   C N S 82  
ASP   C    C N N 83  
ASP   O    O N N 84  
ASP   CB   C N N 85  
ASP   CG   C N N 86  
ASP   OD1  O N N 87  
ASP   OD2  O N N 88  
ASP   OXT  O N N 89  
ASP   H    H N N 90  
ASP   H2   H N N 91  
ASP   HA   H N N 92  
ASP   HB2  H N N 93  
ASP   HB3  H N N 94  
ASP   HD2  H N N 95  
ASP   HXT  H N N 96  
CYS   N    N N N 97  
CYS   CA   C N R 98  
CYS   C    C N N 99  
CYS   O    O N N 100 
CYS   CB   C N N 101 
CYS   SG   S N N 102 
CYS   OXT  O N N 103 
CYS   H    H N N 104 
CYS   H2   H N N 105 
CYS   HA   H N N 106 
CYS   HB2  H N N 107 
CYS   HB3  H N N 108 
CYS   HG   H N N 109 
CYS   HXT  H N N 110 
GLN   N    N N N 111 
GLN   CA   C N S 112 
GLN   C    C N N 113 
GLN   O    O N N 114 
GLN   CB   C N N 115 
GLN   CG   C N N 116 
GLN   CD   C N N 117 
GLN   OE1  O N N 118 
GLN   NE2  N N N 119 
GLN   OXT  O N N 120 
GLN   H    H N N 121 
GLN   H2   H N N 122 
GLN   HA   H N N 123 
GLN   HB2  H N N 124 
GLN   HB3  H N N 125 
GLN   HG2  H N N 126 
GLN   HG3  H N N 127 
GLN   HE21 H N N 128 
GLN   HE22 H N N 129 
GLN   HXT  H N N 130 
GLU   N    N N N 131 
GLU   CA   C N S 132 
GLU   C    C N N 133 
GLU   O    O N N 134 
GLU   CB   C N N 135 
GLU   CG   C N N 136 
GLU   CD   C N N 137 
GLU   OE1  O N N 138 
GLU   OE2  O N N 139 
GLU   OXT  O N N 140 
GLU   H    H N N 141 
GLU   H2   H N N 142 
GLU   HA   H N N 143 
GLU   HB2  H N N 144 
GLU   HB3  H N N 145 
GLU   HG2  H N N 146 
GLU   HG3  H N N 147 
GLU   HE2  H N N 148 
GLU   HXT  H N N 149 
GLY   N    N N N 150 
GLY   CA   C N N 151 
GLY   C    C N N 152 
GLY   O    O N N 153 
GLY   OXT  O N N 154 
GLY   H    H N N 155 
GLY   H2   H N N 156 
GLY   HA2  H N N 157 
GLY   HA3  H N N 158 
GLY   HXT  H N N 159 
HIS   N    N N N 160 
HIS   CA   C N S 161 
HIS   C    C N N 162 
HIS   O    O N N 163 
HIS   CB   C N N 164 
HIS   CG   C Y N 165 
HIS   ND1  N Y N 166 
HIS   CD2  C Y N 167 
HIS   CE1  C Y N 168 
HIS   NE2  N Y N 169 
HIS   OXT  O N N 170 
HIS   H    H N N 171 
HIS   H2   H N N 172 
HIS   HA   H N N 173 
HIS   HB2  H N N 174 
HIS   HB3  H N N 175 
HIS   HD1  H N N 176 
HIS   HD2  H N N 177 
HIS   HE1  H N N 178 
HIS   HE2  H N N 179 
HIS   HXT  H N N 180 
HOH   O    O N N 181 
HOH   H1   H N N 182 
HOH   H2   H N N 183 
ILE   N    N N N 184 
ILE   CA   C N S 185 
ILE   C    C N N 186 
ILE   O    O N N 187 
ILE   CB   C N S 188 
ILE   CG1  C N N 189 
ILE   CG2  C N N 190 
ILE   CD1  C N N 191 
ILE   OXT  O N N 192 
ILE   H    H N N 193 
ILE   H2   H N N 194 
ILE   HA   H N N 195 
ILE   HB   H N N 196 
ILE   HG12 H N N 197 
ILE   HG13 H N N 198 
ILE   HG21 H N N 199 
ILE   HG22 H N N 200 
ILE   HG23 H N N 201 
ILE   HD11 H N N 202 
ILE   HD12 H N N 203 
ILE   HD13 H N N 204 
ILE   HXT  H N N 205 
LEU   N    N N N 206 
LEU   CA   C N S 207 
LEU   C    C N N 208 
LEU   O    O N N 209 
LEU   CB   C N N 210 
LEU   CG   C N N 211 
LEU   CD1  C N N 212 
LEU   CD2  C N N 213 
LEU   OXT  O N N 214 
LEU   H    H N N 215 
LEU   H2   H N N 216 
LEU   HA   H N N 217 
LEU   HB2  H N N 218 
LEU   HB3  H N N 219 
LEU   HG   H N N 220 
LEU   HD11 H N N 221 
LEU   HD12 H N N 222 
LEU   HD13 H N N 223 
LEU   HD21 H N N 224 
LEU   HD22 H N N 225 
LEU   HD23 H N N 226 
LEU   HXT  H N N 227 
LYS   N    N N N 228 
LYS   CA   C N S 229 
LYS   C    C N N 230 
LYS   O    O N N 231 
LYS   CB   C N N 232 
LYS   CG   C N N 233 
LYS   CD   C N N 234 
LYS   CE   C N N 235 
LYS   NZ   N N N 236 
LYS   OXT  O N N 237 
LYS   H    H N N 238 
LYS   H2   H N N 239 
LYS   HA   H N N 240 
LYS   HB2  H N N 241 
LYS   HB3  H N N 242 
LYS   HG2  H N N 243 
LYS   HG3  H N N 244 
LYS   HD2  H N N 245 
LYS   HD3  H N N 246 
LYS   HE2  H N N 247 
LYS   HE3  H N N 248 
LYS   HZ1  H N N 249 
LYS   HZ2  H N N 250 
LYS   HZ3  H N N 251 
LYS   HXT  H N N 252 
MET   N    N N N 253 
MET   CA   C N S 254 
MET   C    C N N 255 
MET   O    O N N 256 
MET   CB   C N N 257 
MET   CG   C N N 258 
MET   SD   S N N 259 
MET   CE   C N N 260 
MET   OXT  O N N 261 
MET   H    H N N 262 
MET   H2   H N N 263 
MET   HA   H N N 264 
MET   HB2  H N N 265 
MET   HB3  H N N 266 
MET   HG2  H N N 267 
MET   HG3  H N N 268 
MET   HE1  H N N 269 
MET   HE2  H N N 270 
MET   HE3  H N N 271 
MET   HXT  H N N 272 
PHE   N    N N N 273 
PHE   CA   C N S 274 
PHE   C    C N N 275 
PHE   O    O N N 276 
PHE   CB   C N N 277 
PHE   CG   C Y N 278 
PHE   CD1  C Y N 279 
PHE   CD2  C Y N 280 
PHE   CE1  C Y N 281 
PHE   CE2  C Y N 282 
PHE   CZ   C Y N 283 
PHE   OXT  O N N 284 
PHE   H    H N N 285 
PHE   H2   H N N 286 
PHE   HA   H N N 287 
PHE   HB2  H N N 288 
PHE   HB3  H N N 289 
PHE   HD1  H N N 290 
PHE   HD2  H N N 291 
PHE   HE1  H N N 292 
PHE   HE2  H N N 293 
PHE   HZ   H N N 294 
PHE   HXT  H N N 295 
PRO   N    N N N 296 
PRO   CA   C N S 297 
PRO   C    C N N 298 
PRO   O    O N N 299 
PRO   CB   C N N 300 
PRO   CG   C N N 301 
PRO   CD   C N N 302 
PRO   OXT  O N N 303 
PRO   H    H N N 304 
PRO   HA   H N N 305 
PRO   HB2  H N N 306 
PRO   HB3  H N N 307 
PRO   HG2  H N N 308 
PRO   HG3  H N N 309 
PRO   HD2  H N N 310 
PRO   HD3  H N N 311 
PRO   HXT  H N N 312 
SER   N    N N N 313 
SER   CA   C N S 314 
SER   C    C N N 315 
SER   O    O N N 316 
SER   CB   C N N 317 
SER   OG   O N N 318 
SER   OXT  O N N 319 
SER   H    H N N 320 
SER   H2   H N N 321 
SER   HA   H N N 322 
SER   HB2  H N N 323 
SER   HB3  H N N 324 
SER   HG   H N N 325 
SER   HXT  H N N 326 
THR   N    N N N 327 
THR   CA   C N S 328 
THR   C    C N N 329 
THR   O    O N N 330 
THR   CB   C N R 331 
THR   OG1  O N N 332 
THR   CG2  C N N 333 
THR   OXT  O N N 334 
THR   H    H N N 335 
THR   H2   H N N 336 
THR   HA   H N N 337 
THR   HB   H N N 338 
THR   HG1  H N N 339 
THR   HG21 H N N 340 
THR   HG22 H N N 341 
THR   HG23 H N N 342 
THR   HXT  H N N 343 
TYR   N    N N N 344 
TYR   CA   C N S 345 
TYR   C    C N N 346 
TYR   O    O N N 347 
TYR   CB   C N N 348 
TYR   CG   C Y N 349 
TYR   CD1  C Y N 350 
TYR   CD2  C Y N 351 
TYR   CE1  C Y N 352 
TYR   CE2  C Y N 353 
TYR   CZ   C Y N 354 
TYR   OH   O N N 355 
TYR   OXT  O N N 356 
TYR   H    H N N 357 
TYR   H2   H N N 358 
TYR   HA   H N N 359 
TYR   HB2  H N N 360 
TYR   HB3  H N N 361 
TYR   HD1  H N N 362 
TYR   HD2  H N N 363 
TYR   HE1  H N N 364 
TYR   HE2  H N N 365 
TYR   HH   H N N 366 
TYR   HXT  H N N 367 
VAL   N    N N N 368 
VAL   CA   C N S 369 
VAL   C    C N N 370 
VAL   O    O N N 371 
VAL   CB   C N N 372 
VAL   CG1  C N N 373 
VAL   CG2  C N N 374 
VAL   OXT  O N N 375 
VAL   H    H N N 376 
VAL   H2   H N N 377 
VAL   HA   H N N 378 
VAL   HB   H N N 379 
VAL   HG11 H N N 380 
VAL   HG12 H N N 381 
VAL   HG13 H N N 382 
VAL   HG21 H N N 383 
VAL   HG22 H N N 384 
VAL   HG23 H N N 385 
VAL   HXT  H N N 386 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1A7V N   CA   sing N N 1   
A1A7V O   C    doub N N 2   
A1A7V C   CA   sing N N 3   
A1A7V CA  CB   sing N N 4   
A1A7V CB  SG   sing N N 5   
A1A7V SG  C1   sing N N 6   
A1A7V O1  C1   doub N N 7   
A1A7V O2  C2   sing N N 8   
A1A7V C1  C2   sing N N 9   
A1A7V C2  C3   sing N N 10  
A1A7V N   H    sing N N 11  
A1A7V N   H2   sing N N 12  
A1A7V CA  HA   sing N N 13  
A1A7V CB  HB3  sing N N 14  
A1A7V CB  HB2  sing N N 15  
A1A7V C2  H20  sing N N 16  
A1A7V O2  HO2  sing N N 17  
A1A7V C3  H3B  sing N N 18  
A1A7V C3  H3A  sing N N 19  
A1A7V C3  H3   sing N N 20  
A1A7V C   OXT  sing N N 21  
A1A7V OXT HXT  sing N N 22  
ALA   N   CA   sing N N 23  
ALA   N   H    sing N N 24  
ALA   N   H2   sing N N 25  
ALA   CA  C    sing N N 26  
ALA   CA  CB   sing N N 27  
ALA   CA  HA   sing N N 28  
ALA   C   O    doub N N 29  
ALA   C   OXT  sing N N 30  
ALA   CB  HB1  sing N N 31  
ALA   CB  HB2  sing N N 32  
ALA   CB  HB3  sing N N 33  
ALA   OXT HXT  sing N N 34  
ARG   N   CA   sing N N 35  
ARG   N   H    sing N N 36  
ARG   N   H2   sing N N 37  
ARG   CA  C    sing N N 38  
ARG   CA  CB   sing N N 39  
ARG   CA  HA   sing N N 40  
ARG   C   O    doub N N 41  
ARG   C   OXT  sing N N 42  
ARG   CB  CG   sing N N 43  
ARG   CB  HB2  sing N N 44  
ARG   CB  HB3  sing N N 45  
ARG   CG  CD   sing N N 46  
ARG   CG  HG2  sing N N 47  
ARG   CG  HG3  sing N N 48  
ARG   CD  NE   sing N N 49  
ARG   CD  HD2  sing N N 50  
ARG   CD  HD3  sing N N 51  
ARG   NE  CZ   sing N N 52  
ARG   NE  HE   sing N N 53  
ARG   CZ  NH1  sing N N 54  
ARG   CZ  NH2  doub N N 55  
ARG   NH1 HH11 sing N N 56  
ARG   NH1 HH12 sing N N 57  
ARG   NH2 HH21 sing N N 58  
ARG   NH2 HH22 sing N N 59  
ARG   OXT HXT  sing N N 60  
ASN   N   CA   sing N N 61  
ASN   N   H    sing N N 62  
ASN   N   H2   sing N N 63  
ASN   CA  C    sing N N 64  
ASN   CA  CB   sing N N 65  
ASN   CA  HA   sing N N 66  
ASN   C   O    doub N N 67  
ASN   C   OXT  sing N N 68  
ASN   CB  CG   sing N N 69  
ASN   CB  HB2  sing N N 70  
ASN   CB  HB3  sing N N 71  
ASN   CG  OD1  doub N N 72  
ASN   CG  ND2  sing N N 73  
ASN   ND2 HD21 sing N N 74  
ASN   ND2 HD22 sing N N 75  
ASN   OXT HXT  sing N N 76  
ASP   N   CA   sing N N 77  
ASP   N   H    sing N N 78  
ASP   N   H2   sing N N 79  
ASP   CA  C    sing N N 80  
ASP   CA  CB   sing N N 81  
ASP   CA  HA   sing N N 82  
ASP   C   O    doub N N 83  
ASP   C   OXT  sing N N 84  
ASP   CB  CG   sing N N 85  
ASP   CB  HB2  sing N N 86  
ASP   CB  HB3  sing N N 87  
ASP   CG  OD1  doub N N 88  
ASP   CG  OD2  sing N N 89  
ASP   OD2 HD2  sing N N 90  
ASP   OXT HXT  sing N N 91  
CYS   N   CA   sing N N 92  
CYS   N   H    sing N N 93  
CYS   N   H2   sing N N 94  
CYS   CA  C    sing N N 95  
CYS   CA  CB   sing N N 96  
CYS   CA  HA   sing N N 97  
CYS   C   O    doub N N 98  
CYS   C   OXT  sing N N 99  
CYS   CB  SG   sing N N 100 
CYS   CB  HB2  sing N N 101 
CYS   CB  HB3  sing N N 102 
CYS   SG  HG   sing N N 103 
CYS   OXT HXT  sing N N 104 
GLN   N   CA   sing N N 105 
GLN   N   H    sing N N 106 
GLN   N   H2   sing N N 107 
GLN   CA  C    sing N N 108 
GLN   CA  CB   sing N N 109 
GLN   CA  HA   sing N N 110 
GLN   C   O    doub N N 111 
GLN   C   OXT  sing N N 112 
GLN   CB  CG   sing N N 113 
GLN   CB  HB2  sing N N 114 
GLN   CB  HB3  sing N N 115 
GLN   CG  CD   sing N N 116 
GLN   CG  HG2  sing N N 117 
GLN   CG  HG3  sing N N 118 
GLN   CD  OE1  doub N N 119 
GLN   CD  NE2  sing N N 120 
GLN   NE2 HE21 sing N N 121 
GLN   NE2 HE22 sing N N 122 
GLN   OXT HXT  sing N N 123 
GLU   N   CA   sing N N 124 
GLU   N   H    sing N N 125 
GLU   N   H2   sing N N 126 
GLU   CA  C    sing N N 127 
GLU   CA  CB   sing N N 128 
GLU   CA  HA   sing N N 129 
GLU   C   O    doub N N 130 
GLU   C   OXT  sing N N 131 
GLU   CB  CG   sing N N 132 
GLU   CB  HB2  sing N N 133 
GLU   CB  HB3  sing N N 134 
GLU   CG  CD   sing N N 135 
GLU   CG  HG2  sing N N 136 
GLU   CG  HG3  sing N N 137 
GLU   CD  OE1  doub N N 138 
GLU   CD  OE2  sing N N 139 
GLU   OE2 HE2  sing N N 140 
GLU   OXT HXT  sing N N 141 
GLY   N   CA   sing N N 142 
GLY   N   H    sing N N 143 
GLY   N   H2   sing N N 144 
GLY   CA  C    sing N N 145 
GLY   CA  HA2  sing N N 146 
GLY   CA  HA3  sing N N 147 
GLY   C   O    doub N N 148 
GLY   C   OXT  sing N N 149 
GLY   OXT HXT  sing N N 150 
HIS   N   CA   sing N N 151 
HIS   N   H    sing N N 152 
HIS   N   H2   sing N N 153 
HIS   CA  C    sing N N 154 
HIS   CA  CB   sing N N 155 
HIS   CA  HA   sing N N 156 
HIS   C   O    doub N N 157 
HIS   C   OXT  sing N N 158 
HIS   CB  CG   sing N N 159 
HIS   CB  HB2  sing N N 160 
HIS   CB  HB3  sing N N 161 
HIS   CG  ND1  sing Y N 162 
HIS   CG  CD2  doub Y N 163 
HIS   ND1 CE1  doub Y N 164 
HIS   ND1 HD1  sing N N 165 
HIS   CD2 NE2  sing Y N 166 
HIS   CD2 HD2  sing N N 167 
HIS   CE1 NE2  sing Y N 168 
HIS   CE1 HE1  sing N N 169 
HIS   NE2 HE2  sing N N 170 
HIS   OXT HXT  sing N N 171 
HOH   O   H1   sing N N 172 
HOH   O   H2   sing N N 173 
ILE   N   CA   sing N N 174 
ILE   N   H    sing N N 175 
ILE   N   H2   sing N N 176 
ILE   CA  C    sing N N 177 
ILE   CA  CB   sing N N 178 
ILE   CA  HA   sing N N 179 
ILE   C   O    doub N N 180 
ILE   C   OXT  sing N N 181 
ILE   CB  CG1  sing N N 182 
ILE   CB  CG2  sing N N 183 
ILE   CB  HB   sing N N 184 
ILE   CG1 CD1  sing N N 185 
ILE   CG1 HG12 sing N N 186 
ILE   CG1 HG13 sing N N 187 
ILE   CG2 HG21 sing N N 188 
ILE   CG2 HG22 sing N N 189 
ILE   CG2 HG23 sing N N 190 
ILE   CD1 HD11 sing N N 191 
ILE   CD1 HD12 sing N N 192 
ILE   CD1 HD13 sing N N 193 
ILE   OXT HXT  sing N N 194 
LEU   N   CA   sing N N 195 
LEU   N   H    sing N N 196 
LEU   N   H2   sing N N 197 
LEU   CA  C    sing N N 198 
LEU   CA  CB   sing N N 199 
LEU   CA  HA   sing N N 200 
LEU   C   O    doub N N 201 
LEU   C   OXT  sing N N 202 
LEU   CB  CG   sing N N 203 
LEU   CB  HB2  sing N N 204 
LEU   CB  HB3  sing N N 205 
LEU   CG  CD1  sing N N 206 
LEU   CG  CD2  sing N N 207 
LEU   CG  HG   sing N N 208 
LEU   CD1 HD11 sing N N 209 
LEU   CD1 HD12 sing N N 210 
LEU   CD1 HD13 sing N N 211 
LEU   CD2 HD21 sing N N 212 
LEU   CD2 HD22 sing N N 213 
LEU   CD2 HD23 sing N N 214 
LEU   OXT HXT  sing N N 215 
LYS   N   CA   sing N N 216 
LYS   N   H    sing N N 217 
LYS   N   H2   sing N N 218 
LYS   CA  C    sing N N 219 
LYS   CA  CB   sing N N 220 
LYS   CA  HA   sing N N 221 
LYS   C   O    doub N N 222 
LYS   C   OXT  sing N N 223 
LYS   CB  CG   sing N N 224 
LYS   CB  HB2  sing N N 225 
LYS   CB  HB3  sing N N 226 
LYS   CG  CD   sing N N 227 
LYS   CG  HG2  sing N N 228 
LYS   CG  HG3  sing N N 229 
LYS   CD  CE   sing N N 230 
LYS   CD  HD2  sing N N 231 
LYS   CD  HD3  sing N N 232 
LYS   CE  NZ   sing N N 233 
LYS   CE  HE2  sing N N 234 
LYS   CE  HE3  sing N N 235 
LYS   NZ  HZ1  sing N N 236 
LYS   NZ  HZ2  sing N N 237 
LYS   NZ  HZ3  sing N N 238 
LYS   OXT HXT  sing N N 239 
MET   N   CA   sing N N 240 
MET   N   H    sing N N 241 
MET   N   H2   sing N N 242 
MET   CA  C    sing N N 243 
MET   CA  CB   sing N N 244 
MET   CA  HA   sing N N 245 
MET   C   O    doub N N 246 
MET   C   OXT  sing N N 247 
MET   CB  CG   sing N N 248 
MET   CB  HB2  sing N N 249 
MET   CB  HB3  sing N N 250 
MET   CG  SD   sing N N 251 
MET   CG  HG2  sing N N 252 
MET   CG  HG3  sing N N 253 
MET   SD  CE   sing N N 254 
MET   CE  HE1  sing N N 255 
MET   CE  HE2  sing N N 256 
MET   CE  HE3  sing N N 257 
MET   OXT HXT  sing N N 258 
PHE   N   CA   sing N N 259 
PHE   N   H    sing N N 260 
PHE   N   H2   sing N N 261 
PHE   CA  C    sing N N 262 
PHE   CA  CB   sing N N 263 
PHE   CA  HA   sing N N 264 
PHE   C   O    doub N N 265 
PHE   C   OXT  sing N N 266 
PHE   CB  CG   sing N N 267 
PHE   CB  HB2  sing N N 268 
PHE   CB  HB3  sing N N 269 
PHE   CG  CD1  doub Y N 270 
PHE   CG  CD2  sing Y N 271 
PHE   CD1 CE1  sing Y N 272 
PHE   CD1 HD1  sing N N 273 
PHE   CD2 CE2  doub Y N 274 
PHE   CD2 HD2  sing N N 275 
PHE   CE1 CZ   doub Y N 276 
PHE   CE1 HE1  sing N N 277 
PHE   CE2 CZ   sing Y N 278 
PHE   CE2 HE2  sing N N 279 
PHE   CZ  HZ   sing N N 280 
PHE   OXT HXT  sing N N 281 
PRO   N   CA   sing N N 282 
PRO   N   CD   sing N N 283 
PRO   N   H    sing N N 284 
PRO   CA  C    sing N N 285 
PRO   CA  CB   sing N N 286 
PRO   CA  HA   sing N N 287 
PRO   C   O    doub N N 288 
PRO   C   OXT  sing N N 289 
PRO   CB  CG   sing N N 290 
PRO   CB  HB2  sing N N 291 
PRO   CB  HB3  sing N N 292 
PRO   CG  CD   sing N N 293 
PRO   CG  HG2  sing N N 294 
PRO   CG  HG3  sing N N 295 
PRO   CD  HD2  sing N N 296 
PRO   CD  HD3  sing N N 297 
PRO   OXT HXT  sing N N 298 
SER   N   CA   sing N N 299 
SER   N   H    sing N N 300 
SER   N   H2   sing N N 301 
SER   CA  C    sing N N 302 
SER   CA  CB   sing N N 303 
SER   CA  HA   sing N N 304 
SER   C   O    doub N N 305 
SER   C   OXT  sing N N 306 
SER   CB  OG   sing N N 307 
SER   CB  HB2  sing N N 308 
SER   CB  HB3  sing N N 309 
SER   OG  HG   sing N N 310 
SER   OXT HXT  sing N N 311 
THR   N   CA   sing N N 312 
THR   N   H    sing N N 313 
THR   N   H2   sing N N 314 
THR   CA  C    sing N N 315 
THR   CA  CB   sing N N 316 
THR   CA  HA   sing N N 317 
THR   C   O    doub N N 318 
THR   C   OXT  sing N N 319 
THR   CB  OG1  sing N N 320 
THR   CB  CG2  sing N N 321 
THR   CB  HB   sing N N 322 
THR   OG1 HG1  sing N N 323 
THR   CG2 HG21 sing N N 324 
THR   CG2 HG22 sing N N 325 
THR   CG2 HG23 sing N N 326 
THR   OXT HXT  sing N N 327 
TYR   N   CA   sing N N 328 
TYR   N   H    sing N N 329 
TYR   N   H2   sing N N 330 
TYR   CA  C    sing N N 331 
TYR   CA  CB   sing N N 332 
TYR   CA  HA   sing N N 333 
TYR   C   O    doub N N 334 
TYR   C   OXT  sing N N 335 
TYR   CB  CG   sing N N 336 
TYR   CB  HB2  sing N N 337 
TYR   CB  HB3  sing N N 338 
TYR   CG  CD1  doub Y N 339 
TYR   CG  CD2  sing Y N 340 
TYR   CD1 CE1  sing Y N 341 
TYR   CD1 HD1  sing N N 342 
TYR   CD2 CE2  doub Y N 343 
TYR   CD2 HD2  sing N N 344 
TYR   CE1 CZ   doub Y N 345 
TYR   CE1 HE1  sing N N 346 
TYR   CE2 CZ   sing Y N 347 
TYR   CE2 HE2  sing N N 348 
TYR   CZ  OH   sing N N 349 
TYR   OH  HH   sing N N 350 
TYR   OXT HXT  sing N N 351 
VAL   N   CA   sing N N 352 
VAL   N   H    sing N N 353 
VAL   N   H2   sing N N 354 
VAL   CA  C    sing N N 355 
VAL   CA  CB   sing N N 356 
VAL   CA  HA   sing N N 357 
VAL   C   O    doub N N 358 
VAL   C   OXT  sing N N 359 
VAL   CB  CG1  sing N N 360 
VAL   CB  CG2  sing N N 361 
VAL   CB  HB   sing N N 362 
VAL   CG1 HG11 sing N N 363 
VAL   CG1 HG12 sing N N 364 
VAL   CG1 HG13 sing N N 365 
VAL   CG2 HG21 sing N N 366 
VAL   CG2 HG22 sing N N 367 
VAL   CG2 HG23 sing N N 368 
VAL   OXT HXT  sing N N 369 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R35GM153337 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          'Unpublished DJ-1 structure from X-ray source' 
# 
_pdbx_serial_crystallography_data_reduction.diffrn_id             1 
_pdbx_serial_crystallography_data_reduction.frames_total          20000 
_pdbx_serial_crystallography_data_reduction.xfel_pulse_events     ? 
_pdbx_serial_crystallography_data_reduction.frame_hits            ? 
_pdbx_serial_crystallography_data_reduction.crystal_hits          1518 
_pdbx_serial_crystallography_data_reduction.droplet_hits          ? 
_pdbx_serial_crystallography_data_reduction.frames_failed_index   ? 
_pdbx_serial_crystallography_data_reduction.frames_indexed        1477 
_pdbx_serial_crystallography_data_reduction.lattices_indexed      ? 
_pdbx_serial_crystallography_data_reduction.xfel_run_numbers      ? 
_pdbx_serial_crystallography_data_reduction.lattices_merged       ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   'concentric flow microfluidic mixer' 
_pdbx_serial_crystallography_sample_delivery.method        injection 
# 
_space_group.name_H-M_alt     'P 31 2 1' 
_space_group.name_Hall        
;P 31 2"
;
_space_group.IT_number        152 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9CGD 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013153 
_atom_sites.fract_transf_matrix[1][2]   0.007594 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015187 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013134 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . ALA   A 1 5   ? 31.53240 8.94727   -0.97685 1.000 89.37873  ? 2   ALA   A N    1 
ATOM   2    C CA   . ALA   A 1 5   ? 32.97224 8.76630   -0.82264 1.000 125.48600 ? 2   ALA   A CA   1 
ATOM   3    C C    . ALA   A 1 5   ? 33.32275 8.32408   0.60276  1.000 119.93925 ? 2   ALA   A C    1 
ATOM   4    O O    . ALA   A 1 5   ? 34.49576 8.27616   0.98175  1.000 80.50649  ? 2   ALA   A O    1 
ATOM   5    C CB   . ALA   A 1 5   ? 33.71071 10.06196  -1.18252 1.000 81.08547  ? 2   ALA   A CB   1 
ATOM   6    H HA   . ALA   A 1 5   ? 33.27038 8.07139   -1.43019 1.000 150.60186 ? 2   ALA   A HA   1 
ATOM   7    H HB1  . ALA   A 1 5   ? 34.66428 9.92331   -1.07120 1.000 97.32122  ? 2   ALA   A HB1  1 
ATOM   8    H HB2  . ALA   A 1 5   ? 33.51520 10.29122  -2.10454 1.000 97.32122  ? 2   ALA   A HB2  1 
ATOM   9    H HB3  . ALA   A 1 5   ? 33.40870 10.77147  -0.59406 1.000 97.32122  ? 2   ALA   A HB3  1 
ATOM   10   N N    . SER   A 1 6   ? 32.30374 7.98630   1.38639  1.000 69.08189  ? 3   SER   A N    1 
ATOM   11   C CA   . SER   A 1 6   ? 32.49061 7.61121   2.78296  1.000 84.55715  ? 3   SER   A CA   1 
ATOM   12   C C    . SER   A 1 6   ? 32.61493 6.09573   2.90081  1.000 40.85805  ? 3   SER   A C    1 
ATOM   13   O O    . SER   A 1 6   ? 31.78407 5.35862   2.36225  1.000 55.66793  ? 3   SER   A O    1 
ATOM   14   C CB   . SER   A 1 6   ? 31.31677 8.12131   3.62215  1.000 91.93500  ? 3   SER   A CB   1 
ATOM   15   O OG   . SER   A 1 6   ? 31.65416 8.20194   4.99507  1.000 78.29071  ? 3   SER   A OG   1 
ATOM   16   H H    . SER   A 1 6   ? 31.48352 7.96652   1.12861  1.000 82.91692  ? 3   SER   A H    1 
ATOM   17   H HA   . SER   A 1 6   ? 33.30865 8.00505   3.12444  1.000 101.48724 ? 3   SER   A HA   1 
ATOM   18   H HB2  . SER   A 1 6   ? 31.06882 9.00510   3.30856  1.000 110.34066 ? 3   SER   A HB2  1 
ATOM   19   H HB3  . SER   A 1 6   ? 30.56993 7.51102   3.51889  1.000 110.34066 ? 3   SER   A HB3  1 
ATOM   20   H HG   . SER   A 1 6   ? 30.98189 8.43201   5.44309  1.000 93.96751  ? 3   SER   A HG   1 
ATOM   21   N N    . LYS   A 1 7   ? 33.65669 5.63433   3.59550  1.000 48.80275  ? 4   LYS   A N    1 
ATOM   22   C CA   . LYS   A 1 7   ? 33.81644 4.20730   3.85313  1.000 33.18986  ? 4   LYS   A CA   1 
ATOM   23   C C    . LYS   A 1 7   ? 32.81732 3.75583   4.91967  1.000 32.59952  ? 4   LYS   A C    1 
ATOM   24   O O    . LYS   A 1 7   ? 32.34731 4.54253   5.74306  1.000 28.12560  ? 4   LYS   A O    1 
ATOM   25   C CB   . LYS   A 1 7   ? 35.23872 3.89079   4.30133  1.000 34.53831  ? 4   LYS   A CB   1 
ATOM   26   C CG   . LYS   A 1 7   ? 36.33243 4.40113   3.37329  1.000 40.37061  ? 4   LYS   A CG   1 
ATOM   27   C CD   . LYS   A 1 7   ? 36.59289 3.47213   2.19851  1.000 46.46058  ? 4   LYS   A CD   1 
ATOM   28   C CE   . LYS   A 1 7   ? 37.77668 3.98256   1.35322  1.000 54.37859  ? 4   LYS   A CE   1 
ATOM   29   N NZ   . LYS   A 1 7   ? 38.28412 2.98430   0.36233  1.000 80.54002  ? 4   LYS   A NZ   1 
ATOM   30   H H    . LYS   A 1 7   ? 34.28028 6.12590   3.92580  1.000 58.58195  ? 4   LYS   A H    1 
ATOM   31   H HA   . LYS   A 1 7   ? 33.64931 3.70925   3.03771  1.000 39.84648  ? 4   LYS   A HA   1 
ATOM   32   H HB2  . LYS   A 1 7   ? 35.38359 4.29415   5.17151  1.000 41.46463  ? 4   LYS   A HB2  1 
ATOM   33   H HB3  . LYS   A 1 7   ? 35.33451 2.92745   4.36211  1.000 41.46463  ? 4   LYS   A HB3  1 
ATOM   34   H HG2  . LYS   A 1 7   ? 36.06844 5.26455   3.01873  1.000 48.46338  ? 4   LYS   A HG2  1 
ATOM   35   H HG3  . LYS   A 1 7   ? 37.15802 4.48696   3.87521  1.000 48.46338  ? 4   LYS   A HG3  1 
ATOM   36   H HD2  . LYS   A 1 7   ? 36.80863 2.58553   2.52759  1.000 55.77135  ? 4   LYS   A HD2  1 
ATOM   37   H HD3  . LYS   A 1 7   ? 35.80488 3.43389   1.63418  1.000 55.77135  ? 4   LYS   A HD3  1 
ATOM   38   H HE2  . LYS   A 1 7   ? 37.49324 4.76915   0.86145  1.000 65.27297  ? 4   LYS   A HE2  1 
ATOM   39   H HE3  . LYS   A 1 7   ? 38.50985 4.20867   1.94670  1.000 65.27297  ? 4   LYS   A HE3  1 
ATOM   40   H HZ1  . LYS   A 1 7   ? 38.94603 3.33896   -0.11536 1.000 96.66667  ? 4   LYS   A HZ1  1 
ATOM   41   H HZ2  . LYS   A 1 7   ? 38.58783 2.26266   0.78552  1.000 96.66667  ? 4   LYS   A HZ2  1 
ATOM   42   H HZ3  . LYS   A 1 7   ? 37.62839 2.74161   -0.18833 1.000 96.66667  ? 4   LYS   A HZ3  1 
ATOM   43   N N    . ARG   A 1 8   ? 32.50386 2.46239   4.90580  1.000 25.35901  ? 5   ARG   A N    1 
ATOM   44   C CA   . ARG   A 1 8   ? 31.41821 1.90455   5.70578  1.000 28.91262  ? 5   ARG   A CA   1 
ATOM   45   C C    . ARG   A 1 8   ? 31.89113 0.62875   6.38900  1.000 28.18077  ? 5   ARG   A C    1 
ATOM   46   O O    . ARG   A 1 8   ? 32.55772 -0.20668  5.77325  1.000 25.55891  ? 5   ARG   A O    1 
ATOM   47   C CB   . ARG   A 1 8   ? 30.17767 1.62506   4.83222  1.000 37.30882  ? 5   ARG   A CB   1 
ATOM   48   C CG   . ARG   A 1 8   ? 29.84139 2.78035   3.88322  1.000 67.47221  ? 5   ARG   A CG   1 
ATOM   49   C CD   . ARG   A 1 8   ? 28.66810 2.49810   2.95220  1.000 62.52369  ? 5   ARG   A CD   1 
ATOM   50   N NE   . ARG   A 1 8   ? 27.41739 2.42833   3.69264  1.000 78.82176  ? 5   ARG   A NE   1 
ATOM   51   C CZ   . ARG   A 1 8   ? 26.68488 1.33140   3.82858  1.000 100.94921 ? 5   ARG   A CZ   1 
ATOM   52   N NH1  . ARG   A 1 8   ? 27.01933 0.19595   3.23262  1.000 108.13931 ? 5   ARG   A NH1  1 
ATOM   53   N NH2  . ARG   A 1 8   ? 25.58339 1.37790   4.57366  1.000 87.61232  ? 5   ARG   A NH2  1 
ATOM   54   H H    . ARG   A 1 8   ? 32.91525 1.87579   4.43013  1.000 30.44946  ? 5   ARG   A H    1 
ATOM   55   H HA   . ARG   A 1 8   ? 31.16191 2.53124   6.40038  1.000 34.71380  ? 5   ARG   A HA   1 
ATOM   56   H HB2  . ARG   A 1 8   ? 30.34271 0.83455   4.29487  1.000 44.78924  ? 5   ARG   A HB2  1 
ATOM   57   H HB3  . ARG   A 1 8   ? 29.41217 1.47963   5.40993  1.000 44.78924  ? 5   ARG   A HB3  1 
ATOM   58   H HG2  . ARG   A 1 8   ? 29.61599 3.56197   4.41159  1.000 80.98531  ? 5   ARG   A HG2  1 
ATOM   59   H HG3  . ARG   A 1 8   ? 30.61697 2.96564   3.33092  1.000 80.98531  ? 5   ARG   A HG3  1 
ATOM   60   H HD2  . ARG   A 1 8   ? 28.59752 3.20995   2.29708  1.000 75.04709  ? 5   ARG   A HD2  1 
ATOM   61   H HD3  . ARG   A 1 8   ? 28.80789 1.64860   2.50531  1.000 75.04709  ? 5   ARG   A HD3  1 
ATOM   62   H HE   . ARG   A 1 8   ? 27.13370 3.14822   4.06799  1.000 94.60477  ? 5   ARG   A HE   1 
ATOM   63   H HH11 . ARG   A 1 8   ? 27.72605 0.15870   2.74400  1.000 129.78582 ? 5   ARG   A HH11 1 
ATOM   64   H HH12 . ARG   A 1 8   ? 26.52964 -0.50364  3.33450  1.000 129.78582 ? 5   ARG   A HH12 1 
ATOM   65   H HH21 . ARG   A 1 8   ? 25.35549 2.11226   4.95885  1.000 105.15343 ? 5   ARG   A HH21 1 
ATOM   66   H HH22 . ARG   A 1 8   ? 25.09938 0.67359   4.67001  1.000 105.15343 ? 5   ARG   A HH22 1 
ATOM   67   N N    . ALA   A 1 9   ? 31.55688 0.49433   7.66999  1.000 24.67151  ? 6   ALA   A N    1 
ATOM   68   C CA   . ALA   A 1 9   ? 31.95040 -0.65365  8.47041  1.000 22.44173  ? 6   ALA   A CA   1 
ATOM   69   C C    . ALA   A 1 9   ? 30.71317 -1.29861  9.06758  1.000 25.49335  ? 6   ALA   A C    1 
ATOM   70   O O    . ALA   A 1 9   ? 29.79243 -0.60559  9.51221  1.000 26.73019  ? 6   ALA   A O    1 
ATOM   71   C CB   . ALA   A 1 9   ? 32.90927 -0.24533  9.59542  1.000 25.45749  ? 6   ALA   A CB   1 
ATOM   72   H H    . ALA   A 1 9   ? 31.09078 1.07147   8.10503  1.000 29.62447  ? 6   ALA   A H    1 
ATOM   73   H HA   . ALA   A 1 9   ? 32.40031 -1.30246  7.90692  1.000 26.94873  ? 6   ALA   A HA   1 
ATOM   74   H HB1  . ALA   A 1 9   ? 33.17075 -1.03742  10.09051 1.000 30.56764  ? 6   ALA   A HB1  1 
ATOM   75   H HB2  . ALA   A 1 9   ? 33.69209 0.17487   9.20617  1.000 30.56764  ? 6   ALA   A HB2  1 
ATOM   76   H HB3  . ALA   A 1 9   ? 32.45733 0.37880   10.18458 1.000 30.56764  ? 6   ALA   A HB3  1 
ATOM   77   N N    . LEU   A 1 10  ? 30.70135 -2.62742  9.07112  1.000 24.33565  ? 7   LEU   A N    1 
ATOM   78   C CA   . LEU   A 1 10  ? 29.65922 -3.41915  9.70773  1.000 19.81110  ? 7   LEU   A CA   1 
ATOM   79   C C    . LEU   A 1 10  ? 30.27677 -4.12540  10.89920 1.000 24.41588  ? 7   LEU   A C    1 
ATOM   80   O O    . LEU   A 1 10  ? 31.22294 -4.89896  10.73461 1.000 20.77960  ? 7   LEU   A O    1 
ATOM   81   C CB   . LEU   A 1 10  ? 29.07006 -4.43818  8.73990  1.000 22.93549  ? 7   LEU   A CB   1 
ATOM   82   C CG   . LEU   A 1 10  ? 28.03526 -5.36616  9.36933  1.000 30.42749  ? 7   LEU   A CG   1 
ATOM   83   C CD1  . LEU   A 1 10  ? 26.80169 -4.56785  9.74701  1.000 34.05687  ? 7   LEU   A CD1  1 
ATOM   84   C CD2  . LEU   A 1 10  ? 27.68806 -6.48040  8.42572  1.000 32.66360  ? 7   LEU   A CD2  1 
ATOM   85   H H    . LEU   A 1 10  ? 31.30880 -3.10801  8.69742  1.000 29.22143  ? 7   LEU   A H    1 
ATOM   86   H HA   . LEU   A 1 10  ? 28.94240 -2.83908  10.00870 1.000 23.79198  ? 7   LEU   A HA   1 
ATOM   87   H HB2  . LEU   A 1 10  ? 28.63758 -3.96227  8.01370  1.000 27.54124  ? 7   LEU   A HB2  1 
ATOM   88   H HB3  . LEU   A 1 10  ? 29.78944 -4.98905  8.39360  1.000 27.54124  ? 7   LEU   A HB3  1 
ATOM   89   H HG   . LEU   A 1 10  ? 28.39825 -5.76836  10.17393 1.000 36.53165  ? 7   LEU   A HG   1 
ATOM   90   H HD11 . LEU   A 1 10  ? 26.09230 -5.18119  9.99499  1.000 40.88690  ? 7   LEU   A HD11 1 
ATOM   91   H HD12 . LEU   A 1 10  ? 27.01645 -3.99024  10.49610 1.000 40.88690  ? 7   LEU   A HD12 1 
ATOM   92   H HD13 . LEU   A 1 10  ? 26.52597 -4.03361  8.98578  1.000 40.88690  ? 7   LEU   A HD13 1 
ATOM   93   H HD21 . LEU   A 1 10  ? 27.00373 -7.03572  8.83096  1.000 39.21497  ? 7   LEU   A HD21 1 
ATOM   94   H HD22 . LEU   A 1 10  ? 27.35772 -6.10063  7.59654  1.000 39.21497  ? 7   LEU   A HD22 1 
ATOM   95   H HD23 . LEU   A 1 10  ? 28.48356 -7.00823  8.25401  1.000 39.21497  ? 7   LEU   A HD23 1 
ATOM   96   N N    . VAL   A 1 11  ? 29.74466 -3.85855  12.08445 1.000 24.09929  ? 8   VAL   A N    1 
ATOM   97   C CA   . VAL   A 1 11  ? 30.13591 -4.53485  13.31554 1.000 16.43829  ? 8   VAL   A CA   1 
ATOM   98   C C    . VAL   A 1 11  ? 28.97439 -5.41790  13.73166 1.000 22.16782  ? 8   VAL   A C    1 
ATOM   99   O O    . VAL   A 1 11  ? 27.86047 -4.93004  13.93067 1.000 26.41503  ? 8   VAL   A O    1 
ATOM   100  C CB   . VAL   A 1 11  ? 30.49809 -3.52837  14.41630 1.000 20.19685  ? 8   VAL   A CB   1 
ATOM   101  C CG1  . VAL   A 1 11  ? 30.82722 -4.23862  15.69916 1.000 24.17954  ? 8   VAL   A CG1  1 
ATOM   102  C CG2  . VAL   A 1 11  ? 31.64788 -2.67586  13.96533 1.000 20.51103  ? 8   VAL   A CG2  1 
ATOM   103  H H    . VAL   A 1 11  ? 29.13197 -3.26743  12.20603 1.000 28.93780  ? 8   VAL   A H    1 
ATOM   104  H HA   . VAL   A 1 11  ? 30.90982 -5.09734  13.15564 1.000 19.74461  ? 8   VAL   A HA   1 
ATOM   105  H HB   . VAL   A 1 11  ? 29.73640 -2.95295  14.58843 1.000 24.25488  ? 8   VAL   A HB   1 
ATOM   106  H HG11 . VAL   A 1 11  ? 31.22046 -3.60472  16.31918 1.000 29.03411  ? 8   VAL   A HG11 1 
ATOM   107  H HG12 . VAL   A 1 11  ? 30.01195 -4.60633  16.07469 1.000 29.03411  ? 8   VAL   A HG12 1 
ATOM   108  H HG13 . VAL   A 1 11  ? 31.45673 -4.95256  15.51233 1.000 29.03411  ? 8   VAL   A HG13 1 
ATOM   109  H HG21 . VAL   A 1 11  ? 31.70232 -1.89227  14.53448 1.000 24.63189  ? 8   VAL   A HG21 1 
ATOM   110  H HG22 . VAL   A 1 11  ? 32.46752 -3.19036  14.03155 1.000 24.63189  ? 8   VAL   A HG22 1 
ATOM   111  H HG23 . VAL   A 1 11  ? 31.49968 -2.40675  13.04527 1.000 24.63189  ? 8   VAL   A HG23 1 
ATOM   112  N N    . ILE   A 1 12  ? 29.22449 -6.71466  13.85994 1.000 19.35495  ? 9   ILE   A N    1 
ATOM   113  C CA   . ILE   A 1 12  ? 28.17852 -7.68264  14.16034 1.000 21.00689  ? 9   ILE   A CA   1 
ATOM   114  C C    . ILE   A 1 12  ? 28.23016 -7.98750  15.64646 1.000 24.84405  ? 9   ILE   A C    1 
ATOM   115  O O    . ILE   A 1 12  ? 29.24550 -8.48687  16.15177 1.000 25.63165  ? 9   ILE   A O    1 
ATOM   116  C CB   . ILE   A 1 12  ? 28.32606 -8.96815  13.32792 1.000 25.43897  ? 9   ILE   A CB   1 
ATOM   117  C CG1  . ILE   A 1 12  ? 28.34101 -8.62988  11.83270 1.000 24.42824  ? 9   ILE   A CG1  1 
ATOM   118  C CG2  . ILE   A 1 12  ? 27.19474 -9.93230  13.65891 1.000 23.05691  ? 9   ILE   A CG2  1 
ATOM   119  C CD1  . ILE   A 1 12  ? 28.49185 -9.82222  10.93577 1.000 29.19476  ? 9   ILE   A CD1  1 
ATOM   120  H H    . ILE   A 1 12  ? 30.00602 -7.06360  13.77588 1.000 23.24459  ? 9   ILE   A H    1 
ATOM   121  H HA   . ILE   A 1 12  ? 27.31679 -7.28833  13.95336 1.000 25.22693  ? 9   ILE   A HA   1 
ATOM   122  H HB   . ILE   A 1 12  ? 29.16856 -9.39488  13.54925 1.000 30.54542  ? 9   ILE   A HB   1 
ATOM   123  H HG12 . ILE   A 1 12  ? 27.50510 -8.19380  11.60471 1.000 29.33255  ? 9   ILE   A HG12 1 
ATOM   124  H HG13 . ILE   A 1 12  ? 29.08525 -8.03314  11.65687 1.000 29.33255  ? 9   ILE   A HG13 1 
ATOM   125  H HG21 . ILE   A 1 12  ? 27.33584 -10.76214 13.17688 1.000 27.68694  ? 9   ILE   A HG21 1 
ATOM   126  H HG22 . ILE   A 1 12  ? 27.19278 -10.10086 14.61415 1.000 27.68694  ? 9   ILE   A HG22 1 
ATOM   127  H HG23 . ILE   A 1 12  ? 26.35177 -9.53372  13.39163 1.000 27.68694  ? 9   ILE   A HG23 1 
ATOM   128  H HD11 . ILE   A 1 12  ? 28.67348 -9.51734  10.03302 1.000 35.05237  ? 9   ILE   A HD11 1 
ATOM   129  H HD12 . ILE   A 1 12  ? 29.22819 -10.36674 11.25545 1.000 35.05237  ? 9   ILE   A HD12 1 
ATOM   130  H HD13 . ILE   A 1 12  ? 27.66915 -10.33584 10.95220 1.000 35.05237  ? 9   ILE   A HD13 1 
ATOM   131  N N    . LEU   A 1 13  ? 27.13337 -7.69978  16.34383 1.000 24.59794  ? 10  LEU   A N    1 
ATOM   132  C CA   . LEU   A 1 13  ? 27.09774 -7.72865  17.79910 1.000 22.56889  ? 10  LEU   A CA   1 
ATOM   133  C C    . LEU   A 1 13  ? 26.14657 -8.81729  18.26259 1.000 27.98791  ? 10  LEU   A C    1 
ATOM   134  O O    . LEU   A 1 13  ? 24.93725 -8.74156  18.01390 1.000 26.83157  ? 10  LEU   A O    1 
ATOM   135  C CB   . LEU   A 1 13  ? 26.67509 -6.36760  18.35458 1.000 25.59978  ? 10  LEU   A CB   1 
ATOM   136  C CG   . LEU   A 1 13  ? 26.46379 -6.29108  19.86935 1.000 33.18199  ? 10  LEU   A CG   1 
ATOM   137  C CD1  . LEU   A 1 13  ? 27.70715 -6.73381  20.60097 1.000 32.91054  ? 10  LEU   A CD1  1 
ATOM   138  C CD2  . LEU   A 1 13  ? 26.08638 -4.88679  20.28602 1.000 30.62109  ? 10  LEU   A CD2  1 
ATOM   139  H H    . LEU   A 1 13  ? 26.38277 -7.48059  15.98584 1.000 29.53619  ? 10  LEU   A H    1 
ATOM   140  H HA   . LEU   A 1 13  ? 27.98048 -7.94569  18.13759 1.000 27.10132  ? 10  LEU   A HA   1 
ATOM   141  H HB2  . LEU   A 1 13  ? 27.36357 -5.72274  18.12867 1.000 30.73840  ? 10  LEU   A HB2  1 
ATOM   142  H HB3  . LEU   A 1 13  ? 25.83655 -6.11814  17.93563 1.000 30.73840  ? 10  LEU   A HB3  1 
ATOM   143  H HG   . LEU   A 1 13  ? 25.73726 -6.88599  20.11256 1.000 39.83704  ? 10  LEU   A HG   1 
ATOM   144  H HD11 . LEU   A 1 13  ? 27.61063 -6.52432  21.54315 1.000 39.51130  ? 10  LEU   A HD11 1 
ATOM   145  H HD12 . LEU   A 1 13  ? 27.81838 -7.69034  20.48450 1.000 39.51130  ? 10  LEU   A HD12 1 
ATOM   146  H HD13 . LEU   A 1 13  ? 28.47305 -6.26470  20.23459 1.000 39.51130  ? 10  LEU   A HD13 1 
ATOM   147  H HD21 . LEU   A 1 13  ? 25.92086 -4.87468  21.24172 1.000 36.76396  ? 10  LEU   A HD21 1 
ATOM   148  H HD22 . LEU   A 1 13  ? 26.81643 -4.28606  20.06912 1.000 36.76396  ? 10  LEU   A HD22 1 
ATOM   149  H HD23 . LEU   A 1 13  ? 25.28547 -4.62010  19.80821 1.000 36.76396  ? 10  LEU   A HD23 1 
ATOM   150  N N    . ALA   A 1 14  ? 26.69282 -9.81786  18.94698 1.000 25.14973  ? 11  ALA   A N    1 
ATOM   151  C CA   . ALA   A 1 14  ? 25.92894 -10.95137 19.44486 1.000 25.79946  ? 11  ALA   A CA   1 
ATOM   152  C C    . ALA   A 1 14  ? 26.04501 -11.05201 20.96049 1.000 29.39287  ? 11  ALA   A C    1 
ATOM   153  O O    . ALA   A 1 14  ? 27.03249 -10.61225 21.56438 1.000 24.94326  ? 11  ALA   A O    1 
ATOM   154  C CB   . ALA   A 1 14  ? 26.41775 -12.26912 18.82460 1.000 23.98658  ? 11  ALA   A CB   1 
ATOM   155  H H    . ALA   A 1 14  ? 27.52973 -9.86156  19.14001 1.000 30.19833  ? 11  ALA   A H    1 
ATOM   156  H HA   . ALA   A 1 14  ? 24.99543 -10.81946 19.21669 1.000 30.97801  ? 11  ALA   A HA   1 
ATOM   157  H HB1  . ALA   A 1 14  ? 25.88671 -13.00025 19.17722 1.000 28.80255  ? 11  ALA   A HB1  1 
ATOM   158  H HB2  . ALA   A 1 14  ? 26.31641 -12.22136 17.86109 1.000 28.80255  ? 11  ALA   A HB2  1 
ATOM   159  H HB3  . ALA   A 1 14  ? 27.35158 -12.39839 19.05298 1.000 28.80255  ? 11  ALA   A HB3  1 
ATOM   160  N N    . LYS   A 1 15  ? 25.03411 -11.66109 21.56976 1.000 26.95807  ? 12  LYS   A N    1 
ATOM   161  C CA   . LYS   A 1 15  ? 25.06913 -11.87476 23.00506 1.000 24.62315  ? 12  LYS   A CA   1 
ATOM   162  C C    . LYS   A 1 15  ? 26.36352 -12.57947 23.38487 1.000 19.43375  ? 12  LYS   A C    1 
ATOM   163  O O    . LYS   A 1 15  ? 26.81179 -13.50279 22.70305 1.000 22.59776  ? 12  LYS   A O    1 
ATOM   164  C CB   . LYS   A 1 15  ? 23.86225 -12.70110 23.45392 1.000 27.81501  ? 12  LYS   A CB   1 
ATOM   165  C CG   . LYS   A 1 15  ? 23.76847 -12.83721 24.96926 1.000 35.29691  ? 12  LYS   A CG   1 
ATOM   166  C CD   . LYS   A 1 15  ? 22.59287 -13.70298 25.39171 1.000 46.13286  ? 12  LYS   A CD   1 
ATOM   167  C CE   . LYS   A 1 15  ? 22.32466 -13.58902 26.89046 1.000 52.26016  ? 12  LYS   A CE   1 
ATOM   168  N NZ   . LYS   A 1 15  ? 23.50185 -13.98687 27.72429 1.000 66.01079  ? 12  LYS   A NZ   1 
ATOM   169  H H    . LYS   A 1 15  ? 24.32727 -11.95514 21.17795 1.000 32.36833  ? 12  LYS   A H    1 
ATOM   170  H HA   . LYS   A 1 15  ? 25.02638 -11.02216 23.46566 1.000 29.56643  ? 12  LYS   A HA   1 
ATOM   171  H HB2  . LYS   A 1 15  ? 23.05137 -12.27070 23.14064 1.000 33.39666  ? 12  LYS   A HB2  1 
ATOM   172  H HB3  . LYS   A 1 15  ? 23.93211 -13.59191 23.07647 1.000 33.39666  ? 12  LYS   A HB3  1 
ATOM   173  H HG2  . LYS   A 1 15  ? 24.58162 -13.24660 25.30406 1.000 42.37495  ? 12  LYS   A HG2  1 
ATOM   174  H HG3  . LYS   A 1 15  ? 23.65354 -11.95793 25.36238 1.000 42.37495  ? 12  LYS   A HG3  1 
ATOM   175  H HD2  . LYS   A 1 15  ? 21.79662 -13.41764 24.91688 1.000 55.37808  ? 12  LYS   A HD2  1 
ATOM   176  H HD3  . LYS   A 1 15  ? 22.78696 -14.63091 25.18636 1.000 55.37808  ? 12  LYS   A HD3  1 
ATOM   177  H HE2  . LYS   A 1 15  ? 22.10505 -12.66840 27.10289 1.000 62.73084  ? 12  LYS   A HE2  1 
ATOM   178  H HE3  . LYS   A 1 15  ? 21.58313 -14.16926 27.12360 1.000 62.73084  ? 12  LYS   A HE3  1 
ATOM   179  H HZ1  . LYS   A 1 15  ? 23.32163 -13.85836 28.58633 1.000 79.23161  ? 12  LYS   A HZ1  1 
ATOM   180  H HZ2  . LYS   A 1 15  ? 23.69064 -14.84677 27.59376 1.000 79.23161  ? 12  LYS   A HZ2  1 
ATOM   181  H HZ3  . LYS   A 1 15  ? 24.21164 -13.49829 27.50163 1.000 79.23161  ? 12  LYS   A HZ3  1 
ATOM   182  N N    . GLY   A 1 16  ? 26.96696 -12.13166 24.47466 1.000 24.05264  ? 13  GLY   A N    1 
ATOM   183  C CA   . GLY   A 1 16  ? 28.22364 -12.69961 24.90969 1.000 23.21127  ? 13  GLY   A CA   1 
ATOM   184  C C    . GLY   A 1 16  ? 29.45738 -12.08724 24.29276 1.000 17.67054  ? 13  GLY   A C    1 
ATOM   185  O O    . GLY   A 1 16  ? 30.56890 -12.52395 24.61295 1.000 25.28581  ? 13  GLY   A O    1 
ATOM   186  H H    . GLY   A 1 16  ? 26.66631 -11.50074 24.97581 1.000 28.88182  ? 13  GLY   A H    1 
ATOM   187  H HA2  . GLY   A 1 16  ? 28.29320 -12.59474 25.87149 1.000 27.87218  ? 13  GLY   A HA2  1 
ATOM   188  H HA3  . GLY   A 1 16  ? 28.22595 -13.64535 24.69414 1.000 27.87218  ? 13  GLY   A HA3  1 
ATOM   189  N N    . ALA   A 1 17  ? 29.30572 -11.09612 23.42164 1.000 24.26491  ? 14  ALA   A N    1 
ATOM   190  C CA   . ALA   A 1 17  ? 30.45856 -10.43018 22.83607 1.000 21.74109  ? 14  ALA   A CA   1 
ATOM   191  C C    . ALA   A 1 17  ? 31.25302 -9.67596  23.90196 1.000 26.10767  ? 14  ALA   A C    1 
ATOM   192  O O    . ALA   A 1 17  ? 30.70315 -9.18842  24.89068 1.000 23.28056  ? 14  ALA   A O    1 
ATOM   193  C CB   . ALA   A 1 17  ? 30.02942 -9.44919  21.75908 1.000 24.43401  ? 14  ALA   A CB   1 
ATOM   194  H H    . ALA   A 1 17  ? 28.54706 -10.79184 23.15434 1.000 29.13655  ? 14  ALA   A H    1 
ATOM   195  H HA   . ALA   A 1 17  ? 31.03000 -11.10254 22.43322 1.000 26.10797  ? 14  ALA   A HA   1 
ATOM   196  H HB1  . ALA   A 1 17  ? 30.81897 -9.03870  21.37305 1.000 29.33947  ? 14  ALA   A HB1  1 
ATOM   197  H HB2  . ALA   A 1 17  ? 29.53695 -9.92781  21.07403 1.000 29.33947  ? 14  ALA   A HB2  1 
ATOM   198  H HB3  . ALA   A 1 17  ? 29.46464 -8.76908  22.15829 1.000 29.33947  ? 14  ALA   A HB3  1 
ATOM   199  N N    . GLU   A 1 18  ? 32.55605 -9.57587  23.68153 1.000 18.95956  ? 15  GLU   A N    1 
ATOM   200  C CA   . GLU   A 1 18  ? 33.39545 -8.76207  24.54382 1.000 20.89204  ? 15  GLU   A CA   1 
ATOM   201  C C    . GLU   A 1 18  ? 33.11739 -7.29016  24.27061 1.000 17.39023  ? 15  GLU   A C    1 
ATOM   202  O O    . GLU   A 1 18  ? 33.35015 -6.79714  23.15686 1.000 20.92208  ? 15  GLU   A O    1 
ATOM   203  C CB   . GLU   A 1 18  ? 34.85982 -9.09985  24.31440 1.000 19.79590  ? 15  GLU   A CB   1 
ATOM   204  C CG   . GLU   A 1 18  ? 35.64580 -9.28159  25.61640 1.000 21.68959  ? 15  GLU   A CG   1 
ATOM   205  C CD   . GLU   A 1 18  ? 35.64557 -8.02667  26.47512 1.000 26.60353  ? 15  GLU   A CD   1 
ATOM   206  O OE1  . GLU   A 1 18  ? 35.66151 -6.92495  25.89346 1.000 18.48887  ? 15  GLU   A OE1  1 
ATOM   207  O OE2  . GLU   A 1 18  ? 35.62522 -8.13976  27.72067 1.000 19.78657  ? 15  GLU   A OE2  1 
ATOM   208  H H    . GLU   A 1 18  ? 32.97606 -9.96801  23.04167 1.000 22.77012  ? 15  GLU   A H    1 
ATOM   209  H HA   . GLU   A 1 18  ? 33.19335 -8.94388  25.47495 1.000 25.08910  ? 15  GLU   A HA   1 
ATOM   210  H HB2  . GLU   A 1 18  ? 34.91648 -9.92822  23.81292 1.000 23.77374  ? 15  GLU   A HB2  1 
ATOM   211  H HB3  . GLU   A 1 18  ? 35.27374 -8.37975  23.81339 1.000 23.77374  ? 15  GLU   A HB3  1 
ATOM   212  H HG2  . GLU   A 1 18  ? 35.24484 -9.99909  26.13149 1.000 26.04616  ? 15  GLU   A HG2  1 
ATOM   213  H HG3  . GLU   A 1 18  ? 36.56642 -9.50054  25.40328 1.000 26.04616  ? 15  GLU   A HG3  1 
ATOM   214  N N    . GLU   A 1 19  ? 32.59784 -6.58557  25.28139 1.000 19.32500  ? 16  GLU   A N    1 
ATOM   215  C CA   . GLU   A 1 19  ? 32.11857 -5.22510  25.03753 1.000 21.13694  ? 16  GLU   A CA   1 
ATOM   216  C C    . GLU   A 1 19  ? 33.26462 -4.25640  24.76744 1.000 20.18112  ? 16  GLU   A C    1 
ATOM   217  O O    . GLU   A 1 19  ? 33.07878 -3.28228  24.04030 1.000 17.95657  ? 16  GLU   A O    1 
ATOM   218  C CB   . GLU   A 1 19  ? 31.26826 -4.73041  26.20925 1.000 19.47254  ? 16  GLU   A CB   1 
ATOM   219  C CG   . GLU   A 1 19  ? 31.81145 -5.03763  27.58471 1.000 25.01609  ? 16  GLU   A CG   1 
ATOM   220  C CD   . GLU   A 1 19  ? 31.27976 -6.34487  28.12025 1.000 24.09123  ? 16  GLU   A CD   1 
ATOM   221  O OE1  . GLU   A 1 19  ? 31.74511 -7.41174  27.66696 1.000 21.08990  ? 16  GLU   A OE1  1 
ATOM   222  O OE2  . GLU   A 1 19  ? 30.38803 -6.30975  28.98485 1.000 22.42667  ? 16  GLU   A OE2  1 
ATOM   223  H H    . GLU   A 1 19  ? 32.51465 -6.86392  26.09083 1.000 23.20865  ? 16  GLU   A H    1 
ATOM   224  H HA   . GLU   A 1 19  ? 31.55091 -5.24344  24.25119 1.000 25.38298  ? 16  GLU   A HA   1 
ATOM   225  H HB2  . GLU   A 1 19  ? 31.18608 -3.76635  26.14043 1.000 23.38570  ? 16  GLU   A HB2  1 
ATOM   226  H HB3  . GLU   A 1 19  ? 30.39282 -5.14335  26.14613 1.000 23.38570  ? 16  GLU   A HB3  1 
ATOM   227  H HG2  . GLU   A 1 19  ? 32.77850 -5.09863  27.54002 1.000 30.03797  ? 16  GLU   A HG2  1 
ATOM   228  H HG3  . GLU   A 1 19  ? 31.55152 -4.33082  28.19606 1.000 30.03797  ? 16  GLU   A HG3  1 
ATOM   229  N N    . MET   A 1 20  ? 34.45192 -4.50229  25.33035 1.000 23.22611  ? 17  MET   A N    1 
ATOM   230  C CA   . MET   A 1 20  ? 35.58770 -3.63935  25.02289 1.000 20.75295  ? 17  MET   A CA   1 
ATOM   231  C C    . MET   A 1 20  ? 36.02187 -3.81053  23.56892 1.000 21.12437  ? 17  MET   A C    1 
ATOM   232  O O    . MET   A 1 20  ? 36.34134 -2.82534  22.89097 1.000 16.12664  ? 17  MET   A O    1 
ATOM   233  C CB   . MET   A 1 20  ? 36.74798 -3.92853  25.97159 1.000 15.01512  ? 17  MET   A CB   1 
ATOM   234  C CG   . MET   A 1 20  ? 36.48082 -3.65398  27.43758 1.000 20.06369  ? 17  MET   A CG   1 
ATOM   235  S SD   . MET   A 1 20  ? 38.00092 -3.82454  28.40589 1.000 22.45834  ? 17  MET   A SD   1 
ATOM   236  C CE   . MET   A 1 20  ? 38.22115 -5.60238  28.49569 1.000 24.14683  ? 17  MET   A CE   1 
ATOM   237  H H    . MET   A 1 20  ? 34.61880 -5.14444  25.87751 1.000 27.88999  ? 17  MET   A H    1 
ATOM   238  H HA   . MET   A 1 20  ? 35.32300 -2.71719  25.16584 1.000 24.92219  ? 17  MET   A HA   1 
ATOM   239  H HB2  . MET   A 1 20  ? 36.97965 -4.86708  25.89192 1.000 18.03680  ? 17  MET   A HB2  1 
ATOM   240  H HB3  . MET   A 1 20  ? 37.50135 -3.37731  25.70799 1.000 18.03680  ? 17  MET   A HB3  1 
ATOM   241  H HG2  . MET   A 1 20  ? 36.14765 -2.74905  27.54247 1.000 24.09508  ? 17  MET   A HG2  1 
ATOM   242  H HG3  . MET   A 1 20  ? 35.82829 -4.28868  27.77261 1.000 24.09508  ? 17  MET   A HG3  1 
ATOM   243  H HE1  . MET   A 1 20  ? 37.86987 -5.92178  29.34155 1.000 28.99485  ? 17  MET   A HE1  1 
ATOM   244  H HE2  . MET   A 1 20  ? 37.74274 -6.01737  27.76098 1.000 28.99485  ? 17  MET   A HE2  1 
ATOM   245  H HE3  . MET   A 1 20  ? 39.16718 -5.80702  28.43197 1.000 28.99485  ? 17  MET   A HE3  1 
ATOM   246  N N    . GLU   A 1 21  ? 36.00692 -5.04721  23.06511 1.000 24.25744  ? 18  GLU   A N    1 
ATOM   247  C CA   . GLU   A 1 21  ? 36.38454 -5.33917  21.68373 1.000 19.07883  ? 18  GLU   A CA   1 
ATOM   248  C C    . GLU   A 1 21  ? 35.34529 -4.86305  20.67706 1.000 21.09583  ? 18  GLU   A C    1 
ATOM   249  O O    . GLU   A 1 21  ? 35.63543 -4.81041  19.47514 1.000 21.51785  ? 18  GLU   A O    1 
ATOM   250  C CB   . GLU   A 1 21  ? 36.61422 -6.84613  21.51842 1.000 20.59413  ? 18  GLU   A CB   1 
ATOM   251  C CG   . GLU   A 1 21  ? 37.74224 -7.36878  22.40633 1.000 22.86320  ? 18  GLU   A CG   1 
ATOM   252  C CD   . GLU   A 1 21  ? 37.81534 -8.88796  22.43548 1.000 26.78834  ? 18  GLU   A CD   1 
ATOM   253  O OE1  . GLU   A 1 21  ? 37.19588 -9.53723  21.57336 1.000 24.69419  ? 18  GLU   A OE1  1 
ATOM   254  O OE2  . GLU   A 1 21  ? 38.49695 -9.42508  23.32871 1.000 23.33124  ? 18  GLU   A OE2  1 
ATOM   255  H H    . GLU   A 1 21  ? 35.77779 -5.74567  23.51149 1.000 29.12758  ? 18  GLU   A H    1 
ATOM   256  H HA   . GLU   A 1 21  ? 37.21747 -4.88395  21.48398 1.000 22.91325  ? 18  GLU   A HA   1 
ATOM   257  H HB2  . GLU   A 1 21  ? 35.80074 -7.31801  21.75609 1.000 24.73161  ? 18  GLU   A HB2  1 
ATOM   258  H HB3  . GLU   A 1 21  ? 36.84740 -7.03114  20.59523 1.000 24.73161  ? 18  GLU   A HB3  1 
ATOM   259  H HG2  . GLU   A 1 21  ? 38.58879 -7.03452  22.07088 1.000 27.45449  ? 18  GLU   A HG2  1 
ATOM   260  H HG3  . GLU   A 1 21  ? 37.59921 -7.05828  23.31410 1.000 27.45449  ? 18  GLU   A HG3  1 
ATOM   261  N N    . THR   A 1 22  ? 34.15419 -4.51933  21.14311 1.000 19.21652  ? 19  THR   A N    1 
ATOM   262  C CA   . THR   A 1 22  ? 33.11362 -3.93781  20.30664 1.000 20.20404  ? 19  THR   A CA   1 
ATOM   263  C C    . THR   A 1 22  ? 33.20785 -2.41167  20.29020 1.000 22.65519  ? 19  THR   A C    1 
ATOM   264  O O    . THR   A 1 22  ? 33.18992 -1.79571  19.21584 1.000 24.61707  ? 19  THR   A O    1 
ATOM   265  C CB   . THR   A 1 22  ? 31.74146 -4.38842  20.82040 1.000 25.93360  ? 19  THR   A CB   1 
ATOM   266  O OG1  . THR   A 1 22  ? 31.65636 -5.81858  20.76736 1.000 21.75391  ? 19  THR   A OG1  1 
ATOM   267  C CG2  . THR   A 1 22  ? 30.63005 -3.80135  19.98603 1.000 26.51297  ? 19  THR   A CG2  1 
ATOM   268  H H    . THR   A 1 22  ? 33.91585 -4.61507  21.96386 1.000 23.07848  ? 19  THR   A H    1 
ATOM   269  H HA   . THR   A 1 22  ? 33.21010 -4.25285  19.39432 1.000 24.26351  ? 19  THR   A HA   1 
ATOM   270  H HB   . THR   A 1 22  ? 31.63010 -4.08297  21.73429 1.000 31.13898  ? 19  THR   A HB   1 
ATOM   271  H HG1  . THR   A 1 22  ? 32.24985 -6.15995  21.25403 1.000 26.12334  ? 19  THR   A HG1  1 
ATOM   272  H HG21 . THR   A 1 22  ? 29.78277 -4.20543  20.23044 1.000 31.83421  ? 19  THR   A HG21 1 
ATOM   273  H HG22 . THR   A 1 22  ? 30.57592 -2.84391  20.13194 1.000 31.83421  ? 19  THR   A HG22 1 
ATOM   274  H HG23 . THR   A 1 22  ? 30.79826 -3.96740  19.04527 1.000 31.83421  ? 19  THR   A HG23 1 
ATOM   275  N N    . VAL   A 1 23  ? 33.34624 -1.79564  21.47153 1.000 23.12577  ? 20  VAL   A N    1 
ATOM   276  C CA   . VAL   A 1 23  ? 33.22776 -0.34532  21.56964 1.000 22.51283  ? 20  VAL   A CA   1 
ATOM   277  C C    . VAL   A 1 23  ? 34.48193 0.35201   21.06910 1.000 19.62998  ? 20  VAL   A C    1 
ATOM   278  O O    . VAL   A 1 23  ? 34.40426 1.40154   20.42434 1.000 18.67251  ? 20  VAL   A O    1 
ATOM   279  C CB   . VAL   A 1 23  ? 32.90441 0.06073   23.01510 1.000 24.61876  ? 20  VAL   A CB   1 
ATOM   280  C CG1  . VAL   A 1 23  ? 33.02750 1.57222   23.18033 1.000 33.68372  ? 20  VAL   A CG1  1 
ATOM   281  C CG2  . VAL   A 1 23  ? 31.50749 -0.42595  23.38566 1.000 22.74705  ? 20  VAL   A CG2  1 
ATOM   282  H H    . VAL   A 1 23  ? 33.50663 -2.19266  22.21735 1.000 27.76958  ? 20  VAL   A H    1 
ATOM   283  H HA   . VAL   A 1 23  ? 32.49340 -0.06831  20.99967 1.000 27.03405  ? 20  VAL   A HA   1 
ATOM   284  H HB   . VAL   A 1 23  ? 33.53877 -0.35192  23.62190 1.000 29.56117  ? 20  VAL   A HB   1 
ATOM   285  H HG11 . VAL   A 1 23  ? 33.96183 1.80124   23.30477 1.000 40.43912  ? 20  VAL   A HG11 1 
ATOM   286  H HG12 . VAL   A 1 23  ? 32.68387 2.00601   22.38369 1.000 40.43912  ? 20  VAL   A HG12 1 
ATOM   287  H HG13 . VAL   A 1 23  ? 32.51326 1.84812   23.95514 1.000 40.43912  ? 20  VAL   A HG13 1 
ATOM   288  H HG21 . VAL   A 1 23  ? 31.26685 -0.06440  24.25300 1.000 27.31512  ? 20  VAL   A HG21 1 
ATOM   289  H HG22 . VAL   A 1 23  ? 30.87809 -0.12048  22.71377 1.000 27.31512  ? 20  VAL   A HG22 1 
ATOM   290  H HG23 . VAL   A 1 23  ? 31.50969 -1.39533  23.42042 1.000 27.31512  ? 20  VAL   A HG23 1 
ATOM   291  N N    . ILE   A 1 24  ? 35.65889 -0.19620  21.34974 1.000 18.93060  ? 21  ILE   A N    1 
ATOM   292  C CA   . ILE   A 1 24  ? 36.88720 0.46493   20.90728 1.000 17.90836  ? 21  ILE   A CA   1 
ATOM   293  C C    . ILE   A 1 24  ? 36.91881 0.60503   19.39245 1.000 19.77792  ? 21  ILE   A C    1 
ATOM   294  O O    . ILE   A 1 24  ? 37.13974 1.72727   18.89936 1.000 20.40536  ? 21  ILE   A O    1 
ATOM   295  C CB   . ILE   A 1 24  ? 38.11323 -0.26134  21.47612 1.000 22.16206  ? 21  ILE   A CB   1 
ATOM   296  C CG1  . ILE   A 1 24  ? 38.17483 -0.04212  22.99368 1.000 32.95093  ? 21  ILE   A CG1  1 
ATOM   297  C CG2  . ILE   A 1 24  ? 39.40007 0.26056   20.83282 1.000 25.60252  ? 21  ILE   A CG2  1 
ATOM   298  C CD1  . ILE   A 1 24  ? 39.20674 -0.90865  23.69156 1.000 26.96200  ? 21  ILE   A CD1  1 
ATOM   299  H H    . ILE   A 1 24  ? 35.77451 -0.93014  21.78283 1.000 22.73538  ? 21  ILE   A H    1 
ATOM   300  H HA   . ILE   A 1 24  ? 36.89774 1.35901   21.28332 1.000 21.50869  ? 21  ILE   A HA   1 
ATOM   301  H HB   . ILE   A 1 24  ? 38.02927 -1.20759  21.28001 1.000 26.61313  ? 21  ILE   A HB   1 
ATOM   302  H HG12 . ILE   A 1 24  ? 38.40047 0.88530   23.16650 1.000 39.55977  ? 21  ILE   A HG12 1 
ATOM   303  H HG13 . ILE   A 1 24  ? 37.30713 -0.24901  23.37473 1.000 39.55977  ? 21  ILE   A HG13 1 
ATOM   304  H HG21 . ILE   A 1 24  ? 40.16174 -0.09238  21.31881 1.000 30.74168  ? 21  ILE   A HG21 1 
ATOM   305  H HG22 . ILE   A 1 24  ? 39.43259 -0.03260  19.90875 1.000 30.74168  ? 21  ILE   A HG22 1 
ATOM   306  H HG23 . ILE   A 1 24  ? 39.40249 1.22973   20.87265 1.000 30.74168  ? 21  ILE   A HG23 1 
ATOM   307  H HD11 . ILE   A 1 24  ? 39.01177 -0.92877  24.64155 1.000 32.37305  ? 21  ILE   A HD11 1 
ATOM   308  H HD12 . ILE   A 1 24  ? 39.16455 -1.80621  23.32616 1.000 32.37305  ? 21  ILE   A HD12 1 
ATOM   309  H HD13 . ILE   A 1 24  ? 40.08813 -0.53199  23.54268 1.000 32.37305  ? 21  ILE   A HD13 1 
ATOM   310  N N    . PRO   A 1 25  ? 36.70722 -0.44305  18.59345 1.000 19.31376  ? 22  PRO   A N    1 
ATOM   311  C CA   . PRO   A 1 25  ? 36.76075 -0.24643  17.14130 1.000 23.99311  ? 22  PRO   A CA   1 
ATOM   312  C C    . PRO   A 1 25  ? 35.65370 0.65773   16.64252 1.000 15.64603  ? 22  PRO   A C    1 
ATOM   313  O O    . PRO   A 1 25  ? 35.88812 1.48640   15.75715 1.000 24.17906  ? 22  PRO   A O    1 
ATOM   314  C CB   . PRO   A 1 25  ? 36.62776 -1.66941  16.58889 1.000 26.31434  ? 22  PRO   A CB   1 
ATOM   315  C CG   . PRO   A 1 25  ? 37.04248 -2.54552  17.71100 1.000 22.34955  ? 22  PRO   A CG   1 
ATOM   316  C CD   . PRO   A 1 25  ? 36.58703 -1.86647  18.94758 1.000 19.01468  ? 22  PRO   A CD   1 
ATOM   317  H HA   . PRO   A 1 25  ? 37.62242 0.11478   16.88065 1.000 28.81039  ? 22  PRO   A HA   1 
ATOM   318  H HB2  . PRO   A 1 25  ? 35.70795 -1.84168  16.33358 1.000 31.59587  ? 22  PRO   A HB2  1 
ATOM   319  H HB3  . PRO   A 1 25  ? 37.21170 -1.78395  15.82287 1.000 31.59587  ? 22  PRO   A HB3  1 
ATOM   320  H HG2  . PRO   A 1 25  ? 36.62002 -3.41402  17.62088 1.000 26.83812  ? 22  PRO   A HG2  1 
ATOM   321  H HG3  . PRO   A 1 25  ? 38.00745 -2.64419  17.70915 1.000 26.83812  ? 22  PRO   A HG3  1 
ATOM   322  H HD2  . PRO   A 1 25  ? 35.66767 -2.09759  19.15316 1.000 22.83627  ? 22  PRO   A HD2  1 
ATOM   323  H HD3  . PRO   A 1 25  ? 37.16055 -2.08813  19.69781 1.000 22.83627  ? 22  PRO   A HD3  1 
ATOM   324  N N    . VAL   A 1 26  ? 34.45015 0.53011   17.19437 1.000 18.64152  ? 23  VAL   A N    1 
ATOM   325  C CA   . VAL   A 1 26  ? 33.35698 1.39658   16.76686 1.000 16.65343  ? 23  VAL   A CA   1 
ATOM   326  C C    . VAL   A 1 26  ? 33.72558 2.85496   16.99774 1.000 17.67575  ? 23  VAL   A C    1 
ATOM   327  O O    . VAL   A 1 26  ? 33.60867 3.70230   16.10916 1.000 20.43531  ? 23  VAL   A O    1 
ATOM   328  C CB   . VAL   A 1 26  ? 32.06671 1.01819   17.50805 1.000 13.34438  ? 23  VAL   A CB   1 
ATOM   329  C CG1  . VAL   A 1 26  ? 31.03120 2.13795   17.35430 1.000 22.04122  ? 23  VAL   A CG1  1 
ATOM   330  C CG2  . VAL   A 1 26  ? 31.52562 -0.29693  16.97818 1.000 20.88418  ? 23  VAL   A CG2  1 
ATOM   331  H H    . VAL   A 1 26  ? 34.24414 -0.03852  17.80578 1.000 22.38848  ? 23  VAL   A H    1 
ATOM   332  H HA   . VAL   A 1 26  ? 33.20841 1.27187   15.81645 1.000 20.00278  ? 23  VAL   A HA   1 
ATOM   333  H HB   . VAL   A 1 26  ? 32.25454 0.90504   18.45294 1.000 16.03191  ? 23  VAL   A HB   1 
ATOM   334  H HG11 . VAL   A 1 26  ? 30.14587 1.77269   17.50817 1.000 26.46812  ? 23  VAL   A HG11 1 
ATOM   335  H HG12 . VAL   A 1 26  ? 31.21948 2.83354   18.00361 1.000 26.46812  ? 23  VAL   A HG12 1 
ATOM   336  H HG13 . VAL   A 1 26  ? 31.08825 2.49970   16.45608 1.000 26.46812  ? 23  VAL   A HG13 1 
ATOM   337  H HG21 . VAL   A 1 26  ? 30.69039 -0.49899  17.42813 1.000 25.07967  ? 23  VAL   A HG21 1 
ATOM   338  H HG22 . VAL   A 1 26  ? 31.37556 -0.21492  16.02338 1.000 25.07967  ? 23  VAL   A HG22 1 
ATOM   339  H HG23 . VAL   A 1 26  ? 32.17312 -0.99789  17.15225 1.000 25.07967  ? 23  VAL   A HG23 1 
ATOM   340  N N    . ASP   A 1 27  ? 34.18814 3.15998   18.20418 1.000 23.94734  ? 24  ASP   A N    1 
ATOM   341  C CA   . ASP   A 1 27  ? 34.56814 4.52092   18.56492 1.000 18.82543  ? 24  ASP   A CA   1 
ATOM   342  C C    . ASP   A 1 27  ? 35.69648 5.02455   17.67377 1.000 20.85813  ? 24  ASP   A C    1 
ATOM   343  O O    . ASP   A 1 27  ? 35.58989 6.08522   17.04678 1.000 18.03784  ? 24  ASP   A O    1 
ATOM   344  C CB   . ASP   A 1 27  ? 34.95606 4.51285   20.04714 1.000 21.09227  ? 24  ASP   A CB   1 
ATOM   345  C CG   . ASP   A 1 27  ? 35.19017 5.89540   20.62630 1.000 24.52739  ? 24  ASP   A CG   1 
ATOM   346  O OD1  . ASP   A 1 27  ? 35.81356 6.74367   19.96624 1.000 20.03635  ? 24  ASP   A OD1  1 
ATOM   347  O OD2  . ASP   A 1 27  ? 34.78998 6.10026   21.78854 1.000 21.89081  ? 24  ASP   A OD2  1 
ATOM   348  H H    . ASP   A 1 27  ? 34.29348 2.59165   18.84097 1.000 28.75546  ? 24  ASP   A H    1 
ATOM   349  H HA   . ASP   A 1 27  ? 33.82908 5.13677   18.44075 1.000 22.60917  ? 24  ASP   A HA   1 
ATOM   350  H HB2  . ASP   A 1 27  ? 34.24148 4.09707   20.55448 1.000 25.32938  ? 24  ASP   A HB2  1 
ATOM   351  H HB3  . ASP   A 1 27  ? 35.77618 4.00567   20.15232 1.000 25.32938  ? 24  ASP   A HB3  1 
ATOM   352  N N    . VAL   A 1 28  ? 36.77326 4.25609   17.57475 1.000 18.41270  ? 25  VAL   A N    1 
ATOM   353  C CA   . VAL   A 1 28  ? 37.93000 4.71011   16.81577 1.000 21.75906  ? 25  VAL   A CA   1 
ATOM   354  C C    . VAL   A 1 28  ? 37.57442 4.87753   15.35138 1.000 21.53835  ? 25  VAL   A C    1 
ATOM   355  O O    . VAL   A 1 28  ? 38.04539 5.80363   14.68572 1.000 24.01112  ? 25  VAL   A O    1 
ATOM   356  C CB   . VAL   A 1 28  ? 39.09770 3.72245   16.99702 1.000 18.04883  ? 25  VAL   A CB   1 
ATOM   357  C CG1  . VAL   A 1 28  ? 40.21553 4.03530   16.00782 1.000 24.53505  ? 25  VAL   A CG1  1 
ATOM   358  C CG2  . VAL   A 1 28  ? 39.59885 3.76722   18.43881 1.000 25.25261  ? 25  VAL   A CG2  1 
ATOM   359  H H    . VAL   A 1 28  ? 36.85926 3.47858   17.93208 1.000 22.11389  ? 25  VAL   A H    1 
ATOM   360  H HA   . VAL   A 1 28  ? 38.20264 5.57586   17.15790 1.000 26.12953  ? 25  VAL   A HA   1 
ATOM   361  H HB   . VAL   A 1 28  ? 38.79235 2.81984   16.81545 1.000 21.67725  ? 25  VAL   A HB   1 
ATOM   362  H HG11 . VAL   A 1 28  ? 41.03032 3.60030   16.30410 1.000 29.46072  ? 25  VAL   A HG11 1 
ATOM   363  H HG12 . VAL   A 1 28  ? 39.96362 3.70423   15.13156 1.000 29.46072  ? 25  VAL   A HG12 1 
ATOM   364  H HG13 . VAL   A 1 28  ? 40.34704 4.99573   15.97331 1.000 29.46072  ? 25  VAL   A HG13 1 
ATOM   365  H HG21 . VAL   A 1 28  ? 40.34562 3.15533   18.53272 1.000 30.32179  ? 25  VAL   A HG21 1 
ATOM   366  H HG22 . VAL   A 1 28  ? 39.88363 4.67098   18.64623 1.000 30.32179  ? 25  VAL   A HG22 1 
ATOM   367  H HG23 . VAL   A 1 28  ? 38.87821 3.50314   19.03197 1.000 30.32179  ? 25  VAL   A HG23 1 
ATOM   368  N N    . MET   A 1 29  ? 36.77224 3.96578   14.81561 1.000 18.60166  ? 26  MET   A N    1 
ATOM   369  C CA   . MET   A 1 29  ? 36.40474 4.07636   13.40958 1.000 18.20187  ? 26  MET   A CA   1 
ATOM   370  C C    . MET   A 1 29  ? 35.56899 5.31965   13.15905 1.000 19.93733  ? 26  MET   A C    1 
ATOM   371  O O    . MET   A 1 29  ? 35.74999 5.99619   12.13790 1.000 19.77054  ? 26  MET   A O    1 
ATOM   372  C CB   . MET   A 1 29  ? 35.65808 2.82208   12.95433 1.000 20.04105  ? 26  MET   A CB   1 
ATOM   373  C CG   . MET   A 1 29  ? 36.59610 1.65679   12.63329 1.000 24.58388  ? 26  MET   A CG   1 
ATOM   374  S SD   . MET   A 1 29  ? 35.82329 0.27834   11.77932 1.000 22.91696  ? 26  MET   A SD   1 
ATOM   375  C CE   . MET   A 1 29  ? 34.70566 -0.36224  13.00375 1.000 25.69833  ? 26  MET   A CE   1 
ATOM   376  H H    . MET   A 1 29  ? 36.43603 3.29219   15.23134 1.000 22.34065  ? 26  MET   A H    1 
ATOM   377  H HA   . MET   A 1 29  ? 37.21796 4.13582   12.88419 1.000 21.86089  ? 26  MET   A HA   1 
ATOM   378  H HB2  . MET   A 1 29  ? 35.05791 2.53818   13.66150 1.000 24.06791  ? 26  MET   A HB2  1 
ATOM   379  H HB3  . MET   A 1 29  ? 35.15212 3.02956   12.15317 1.000 24.06791  ? 26  MET   A HB3  1 
ATOM   380  H HG2  . MET   A 1 29  ? 37.31235 1.98495   12.06743 1.000 29.51931  ? 26  MET   A HG2  1 
ATOM   381  H HG3  . MET   A 1 29  ? 36.96018 1.31632   13.46541 1.000 29.51931  ? 26  MET   A HG3  1 
ATOM   382  H HE1  . MET   A 1 29  ? 34.23979 -1.12927  12.63561 1.000 30.85665  ? 26  MET   A HE1  1 
ATOM   383  H HE2  . MET   A 1 29  ? 35.21327 -0.62792  13.78647 1.000 30.85665  ? 26  MET   A HE2  1 
ATOM   384  H HE3  . MET   A 1 29  ? 34.06817 0.32898   13.24187 1.000 30.85665  ? 26  MET   A HE3  1 
ATOM   385  N N    . ARG   A 1 30  ? 34.66236 5.65079   14.08432 1.000 18.25069  ? 27  ARG   A N    1 
ATOM   386  C CA   . ARG   A 1 30  ? 33.86631 6.85835   13.90240 1.000 19.90870  ? 27  ARG   A CA   1 
ATOM   387  C C    . ARG   A 1 30  ? 34.72525 8.10729   14.04278 1.000 19.83249  ? 27  ARG   A C    1 
ATOM   388  O O    . ARG   A 1 30  ? 34.49532 9.08847   13.32926 1.000 22.48379  ? 27  ARG   A O    1 
ATOM   389  C CB   . ARG   A 1 30  ? 32.68334 6.85895   14.86281 1.000 23.77407  ? 27  ARG   A CB   1 
ATOM   390  C CG   . ARG   A 1 30  ? 31.56557 5.90612   14.40954 1.000 25.69790  ? 27  ARG   A CG   1 
ATOM   391  C CD   . ARG   A 1 30  ? 30.39802 5.82819   15.39872 1.000 24.43223  ? 27  ARG   A CD   1 
ATOM   392  N NE   . ARG   A 1 30  ? 29.29269 5.01869   14.89304 1.000 25.82223  ? 27  ARG   A NE   1 
ATOM   393  C CZ   . ARG   A 1 30  ? 28.41814 4.36347   15.65049 1.000 23.89971  ? 27  ARG   A CZ   1 
ATOM   394  N NH1  . ARG   A 1 30  ? 28.45727 4.43064   16.97057 1.000 21.71285  ? 27  ARG   A NH1  1 
ATOM   395  N NH2  . ARG   A 1 30  ? 27.47844 3.62341   15.06870 1.000 25.97990  ? 27  ARG   A NH2  1 
ATOM   396  H H    . ARG   A 1 30  ? 34.49686 5.20581   14.80139 1.000 21.91949  ? 27  ARG   A H    1 
ATOM   397  H HA   . ARG   A 1 30  ? 33.49041 6.87152   13.00830 1.000 23.90910  ? 27  ARG   A HA   1 
ATOM   398  H HB2  . ARG   A 1 30  ? 32.98587 6.57507   15.73961 1.000 28.54754  ? 27  ARG   A HB2  1 
ATOM   399  H HB3  . ARG   A 1 30  ? 32.31529 7.75501   14.91289 1.000 28.54754  ? 27  ARG   A HB3  1 
ATOM   400  H HG2  . ARG   A 1 30  ? 31.21487 6.21463   13.55940 1.000 30.85613  ? 27  ARG   A HG2  1 
ATOM   401  H HG3  . ARG   A 1 30  ? 31.93315 5.01371   14.31259 1.000 30.85613  ? 27  ARG   A HG3  1 
ATOM   402  H HD2  . ARG   A 1 30  ? 30.70917 5.42959   16.22649 1.000 29.33733  ? 27  ARG   A HD2  1 
ATOM   403  H HD3  . ARG   A 1 30  ? 30.06373 6.72315   15.56657 1.000 29.33733  ? 27  ARG   A HD3  1 
ATOM   404  H HE   . ARG   A 1 30  ? 29.20037 4.96140   14.03993 1.000 31.00533  ? 27  ARG   A HE   1 
ATOM   405  H HH11 . ARG   A 1 30  ? 29.05881 4.90674   17.35926 1.000 26.07407  ? 27  ARG   A HH11 1 
ATOM   406  H HH12 . ARG   A 1 30  ? 27.88118 3.99822   17.44039 1.000 26.07407  ? 27  ARG   A HH12 1 
ATOM   407  H HH21 . ARG   A 1 30  ? 27.44099 3.57237   14.21104 1.000 31.19454  ? 27  ARG   A HH21 1 
ATOM   408  H HH22 . ARG   A 1 30  ? 26.90833 3.19596   15.55021 1.000 31.19454  ? 27  ARG   A HH22 1 
ATOM   409  N N    . ARG   A 1 31  ? 35.75291 8.07372   14.89678 1.000 23.92147  ? 28  ARG   A N    1 
ATOM   410  C CA   . ARG   A 1 31  ? 36.69663 9.18059   14.95111 1.000 19.98534  ? 28  ARG   A CA   1 
ATOM   411  C C    . ARG   A 1 31  ? 37.40386 9.36947   13.61759 1.000 22.51279  ? 28  ARG   A C    1 
ATOM   412  O O    . ARG   A 1 31  ? 37.81962 10.48974  13.28538 1.000 21.81013  ? 28  ARG   A O    1 
ATOM   413  C CB   . ARG   A 1 31  ? 37.73544 8.95247   16.05041 1.000 18.78906  ? 28  ARG   A CB   1 
ATOM   414  C CG   . ARG   A 1 31  ? 37.21397 9.09718   17.44673 1.000 26.03606  ? 28  ARG   A CG   1 
ATOM   415  C CD   . ARG   A 1 31  ? 38.25512 8.64185   18.45116 1.000 28.05301  ? 28  ARG   A CD   1 
ATOM   416  N NE   . ARG   A 1 31  ? 37.78790 8.85015   19.81707 1.000 24.88344  ? 28  ARG   A NE   1 
ATOM   417  C CZ   . ARG   A 1 31  ? 38.20556 9.82751   20.61168 1.000 24.19179  ? 28  ARG   A CZ   1 
ATOM   418  N NH1  . ARG   A 1 31  ? 39.14963 10.66884  20.22747 1.000 20.67656  ? 28  ARG   A NH1  1 
ATOM   419  N NH2  . ARG   A 1 31  ? 37.66661 9.95273   21.82409 1.000 22.94226  ? 28  ARG   A NH2  1 
ATOM   420  H H    . ARG   A 1 31  ? 35.91947 7.43138   15.44382 1.000 28.72442  ? 28  ARG   A H    1 
ATOM   421  H HA   . ARG   A 1 31  ? 36.20412 9.98840   15.16506 1.000 24.00106  ? 28  ARG   A HA   1 
ATOM   422  H HB2  . ARG   A 1 31  ? 38.08510 8.05207   15.96142 1.000 22.56552  ? 28  ARG   A HB2  1 
ATOM   423  H HB3  . ARG   A 1 31  ? 38.45008 9.59855   15.93744 1.000 22.56552  ? 28  ARG   A HB3  1 
ATOM   424  H HG2  . ARG   A 1 31  ? 37.00303 10.02791  17.62035 1.000 31.26193  ? 28  ARG   A HG2  1 
ATOM   425  H HG3  . ARG   A 1 31  ? 36.41970 8.55111   17.55555 1.000 31.26193  ? 28  ARG   A HG3  1 
ATOM   426  H HD2  . ARG   A 1 31  ? 38.43163 7.69610   18.32751 1.000 33.68227  ? 28  ARG   A HD2  1 
ATOM   427  H HD3  . ARG   A 1 31  ? 39.07097 9.15097   18.32433 1.000 33.68227  ? 28  ARG   A HD3  1 
ATOM   428  H HE   . ARG   A 1 31  ? 37.20229 8.30271   20.12847 1.000 29.87879  ? 28  ARG   A HE   1 
ATOM   429  H HH11 . ARG   A 1 31  ? 39.50597 10.58891  19.44886 1.000 24.83053  ? 28  ARG   A HH11 1 
ATOM   430  H HH12 . ARG   A 1 31  ? 39.40761 11.29624  20.75607 1.000 24.83053  ? 28  ARG   A HH12 1 
ATOM   431  H HH21 . ARG   A 1 31  ? 37.05660 9.40423   22.08224 1.000 27.54937  ? 28  ARG   A HH21 1 
ATOM   432  H HH22 . ARG   A 1 31  ? 37.92882 10.58204  22.34832 1.000 27.54937  ? 28  ARG   A HH22 1 
ATOM   433  N N    . ALA   A 1 32  ? 37.56165 8.28678   12.84780 1.000 22.47636  ? 29  ALA   A N    1 
ATOM   434  C CA   . ALA   A 1 32  ? 38.19687 8.34690   11.53588 1.000 18.74076  ? 29  ALA   A CA   1 
ATOM   435  C C    . ALA   A 1 32  ? 37.22447 8.71910   10.42962 1.000 21.86204  ? 29  ALA   A C    1 
ATOM   436  O O    . ALA   A 1 32  ? 37.60970 8.72219   9.25706  1.000 26.30136  ? 29  ALA   A O    1 
ATOM   437  C CB   . ALA   A 1 32  ? 38.85132 7.00111   11.20124 1.000 19.12093  ? 29  ALA   A CB   1 
ATOM   438  H H    . ALA   A 1 32  ? 37.30390 7.49715   13.07064 1.000 26.99028  ? 29  ALA   A H    1 
ATOM   439  H HA   . ALA   A 1 32  ? 38.89496 9.01981   11.56369 1.000 22.50757  ? 29  ALA   A HA   1 
ATOM   440  H HB1  . ALA   A 1 32  ? 39.28329 7.06668   10.33521 1.000 22.96377  ? 29  ALA   A HB1  1 
ATOM   441  H HB2  . ALA   A 1 32  ? 39.50813 6.79104   11.88343 1.000 22.96377  ? 29  ALA   A HB2  1 
ATOM   442  H HB3  . ALA   A 1 32  ? 38.16689 6.31414   11.17832 1.000 22.96377  ? 29  ALA   A HB3  1 
ATOM   443  N N    . GLY   A 1 33  ? 35.98298 9.03925   10.76786 1.000 23.67623  ? 30  GLY   A N    1 
ATOM   444  C CA   . GLY   A 1 33  ? 35.02670 9.43265   9.75536  1.000 29.57256  ? 30  GLY   A CA   1 
ATOM   445  C C    . GLY   A 1 33  ? 34.38531 8.28476   9.01449  1.000 39.87947  ? 30  GLY   A C    1 
ATOM   446  O O    . GLY   A 1 33  ? 33.71234 8.51809   8.01066  1.000 25.54164  ? 30  GLY   A O    1 
ATOM   447  H H    . GLY   A 1 33  ? 35.67614 9.03537   11.57125 1.000 28.43013  ? 30  GLY   A H    1 
ATOM   448  H HA2  . GLY   A 1 33  ? 34.31966 9.94533   10.17743 1.000 35.50572  ? 30  GLY   A HA2  1 
ATOM   449  H HA3  . GLY   A 1 33  ? 35.47644 9.99234   9.10315  1.000 35.50572  ? 30  GLY   A HA3  1 
ATOM   450  N N    . ILE   A 1 34  ? 34.57863 7.05496   9.47126  1.000 25.01064  ? 31  ILE   A N    1 
ATOM   451  C CA   . ILE   A 1 34  ? 33.93598 5.89366   8.87084  1.000 27.92689  ? 31  ILE   A CA   1 
ATOM   452  C C    . ILE   A 1 34  ? 32.50096 5.80238   9.36814  1.000 28.43276  ? 31  ILE   A C    1 
ATOM   453  O O    . ILE   A 1 34  ? 32.21154 6.04877   10.54578 1.000 27.70032  ? 31  ILE   A O    1 
ATOM   454  C CB   . ILE   A 1 34  ? 34.73175 4.61942   9.20450  1.000 22.36771  ? 31  ILE   A CB   1 
ATOM   455  C CG1  . ILE   A 1 34  ? 36.13748 4.71680   8.61148  1.000 23.64496  ? 31  ILE   A CG1  1 
ATOM   456  C CG2  . ILE   A 1 34  ? 34.00429 3.38845   8.71919  1.000 24.03681  ? 31  ILE   A CG2  1 
ATOM   457  C CD1  . ILE   A 1 34  ? 37.15007 3.74769   9.23175  1.000 32.16234  ? 31  ILE   A CD1  1 
ATOM   458  H H    . ILE   A 1 34  ? 35.08564 6.86273   10.13878 1.000 30.03143  ? 31  ILE   A H    1 
ATOM   459  H HA   . ILE   A 1 34  ? 33.91506 5.99713   7.90660  1.000 33.53092  ? 31  ILE   A HA   1 
ATOM   460  H HB   . ILE   A 1 34  ? 34.81364 4.54295   10.16801 1.000 26.85991  ? 31  ILE   A HB   1 
ATOM   461  H HG12 . ILE   A 1 34  ? 36.08780 4.52257   7.66243  1.000 28.39261  ? 31  ILE   A HG12 1 
ATOM   462  H HG13 . ILE   A 1 34  ? 36.47026 5.61752   8.74882  1.000 28.39261  ? 31  ILE   A HG13 1 
ATOM   463  H HG21 . ILE   A 1 34  ? 34.56514 2.61109   8.86767  1.000 28.86282  ? 31  ILE   A HG21 1 
ATOM   464  H HG22 . ILE   A 1 34  ? 33.17444 3.29680   9.21301  1.000 28.86282  ? 31  ILE   A HG22 1 
ATOM   465  H HG23 . ILE   A 1 34  ? 33.81684 3.48512   7.77240  1.000 28.86282  ? 31  ILE   A HG23 1 
ATOM   466  H HD11 . ILE   A 1 34  ? 38.04067 3.98554   8.92984  1.000 38.61346  ? 31  ILE   A HD11 1 
ATOM   467  H HD12 . ILE   A 1 34  ? 37.09968 3.81411   10.19816 1.000 38.61346  ? 31  ILE   A HD12 1 
ATOM   468  H HD13 . ILE   A 1 34  ? 36.93576 2.84438   8.95066  1.000 38.61346  ? 31  ILE   A HD13 1 
ATOM   469  N N    . LYS   A 1 35  ? 31.58452 5.48081   8.46458  1.000 23.11991  ? 32  LYS   A N    1 
ATOM   470  C CA   A LYS   A 1 35  ? 30.19513 5.23892   8.83647  0.362 20.53764  ? 32  LYS   A CA   1 
ATOM   471  C CA   B LYS   A 1 35  ? 30.19653 5.24033   8.83925  0.638 19.88481  ? 32  LYS   A CA   1 
ATOM   472  C C    . LYS   A 1 35  ? 30.07998 3.80687   9.33932  1.000 22.31244  ? 32  LYS   A C    1 
ATOM   473  O O    . LYS   A 1 35  ? 30.19627 2.85883   8.55355  1.000 26.06607  ? 32  LYS   A O    1 
ATOM   474  C CB   A LYS   A 1 35  ? 29.26165 5.47836   7.65274  0.362 31.78879  ? 32  LYS   A CB   1 
ATOM   475  C CB   B LYS   A 1 35  ? 29.27681 5.49013   7.64822  0.638 32.16702  ? 32  LYS   A CB   1 
ATOM   476  C CG   A LYS   A 1 35  ? 29.03554 6.94738   7.32034  0.362 36.04775  ? 32  LYS   A CG   1 
ATOM   477  C CG   B LYS   A 1 35  ? 27.80750 5.62719   8.00300  0.638 29.96409  ? 32  LYS   A CG   1 
ATOM   478  C CD   A LYS   A 1 35  ? 27.61037 7.19412   6.83012  0.362 62.78836  ? 32  LYS   A CD   1 
ATOM   479  C CD   B LYS   A 1 35  ? 26.94314 5.79113   6.74335  0.638 58.64153  ? 32  LYS   A CD   1 
ATOM   480  C CE   A LYS   A 1 35  ? 27.56327 7.56338   5.35224  0.362 63.17983  ? 32  LYS   A CE   1 
ATOM   481  C CE   B LYS   A 1 35  ? 27.48160 6.88097   5.80344  0.638 73.84256  ? 32  LYS   A CE   1 
ATOM   482  N NZ   A LYS   A 1 35  ? 26.15540 7.66222   4.85927  0.362 68.77170  ? 32  LYS   A NZ   1 
ATOM   483  N NZ   B LYS   A 1 35  ? 26.57656 7.16251   4.64547  0.638 82.05307  ? 32  LYS   A NZ   1 
ATOM   484  H H    A LYS   A 1 35  ? 31.74234 5.39562   7.62349  0.362 27.76255  ? 32  LYS   A H    1 
ATOM   485  H H    B LYS   A 1 35  ? 31.74170 5.39507   7.62342  0.638 27.76255  ? 32  LYS   A H    1 
ATOM   486  H HA   A LYS   A 1 35  ? 29.93911 5.85044   9.54456  0.362 24.66383  ? 32  LYS   A HA   1 
ATOM   487  H HA   B LYS   A 1 35  ? 29.93456 5.84301   9.55272  0.638 23.88042  ? 32  LYS   A HA   1 
ATOM   488  H HB2  A LYS   A 1 35  ? 29.64218 5.05458   6.86756  0.362 38.16521  ? 32  LYS   A HB2  1 
ATOM   489  H HB2  B LYS   A 1 35  ? 29.55096 6.31299   7.21388  0.638 38.61908  ? 32  LYS   A HB2  1 
ATOM   490  H HB3  A LYS   A 1 35  ? 28.39775 5.08656   7.85537  0.362 38.16521  ? 32  LYS   A HB3  1 
ATOM   491  H HB3  B LYS   A 1 35  ? 29.36084 4.74577   7.03198  0.638 38.61908  ? 32  LYS   A HB3  1 
ATOM   492  H HG2  A LYS   A 1 35  ? 29.18213 7.48346   8.11534  0.362 43.27596  ? 32  LYS   A HG2  1 
ATOM   493  H HG2  B LYS   A 1 35  ? 27.51412 4.83148   8.47383  0.638 35.97556  ? 32  LYS   A HG2  1 
ATOM   494  H HG3  A LYS   A 1 35  ? 29.65031 7.21721   6.62024  0.362 43.27596  ? 32  LYS   A HG3  1 
ATOM   495  H HG3  B LYS   A 1 35  ? 27.68290 6.40911   8.56333  0.638 35.97556  ? 32  LYS   A HG3  1 
ATOM   496  H HD2  A LYS   A 1 35  ? 27.08629 6.38769   6.95626  0.362 75.36468  ? 32  LYS   A HD2  1 
ATOM   497  H HD2  B LYS   A 1 35  ? 26.92920 4.95269   6.25578  0.638 70.38850  ? 32  LYS   A HD2  1 
ATOM   498  H HD3  A LYS   A 1 35  ? 27.22179 7.92484   7.33602  0.362 75.36468  ? 32  LYS   A HD3  1 
ATOM   499  H HD3  B LYS   A 1 35  ? 26.04232 6.03746   7.00552  0.638 70.38850  ? 32  LYS   A HD3  1 
ATOM   500  H HE2  A LYS   A 1 35  ? 27.99365 8.42283   5.22172  0.362 75.83445  ? 32  LYS   A HE2  1 
ATOM   501  H HE2  B LYS   A 1 35  ? 27.58793 7.70435   6.30509  0.638 88.62972  ? 32  LYS   A HE2  1 
ATOM   502  H HE3  A LYS   A 1 35  ? 28.02060 6.88149   4.83574  0.362 75.83445  ? 32  LYS   A HE3  1 
ATOM   503  H HE3  B LYS   A 1 35  ? 28.33821 6.59541   5.44908  0.638 88.62972  ? 32  LYS   A HE3  1 
ATOM   504  H HZ1  A LYS   A 1 35  ? 26.14693 7.95643   4.01934  0.362 82.54469  ? 32  LYS   A HZ1  1 
ATOM   505  H HZ1  B LYS   A 1 35  ? 26.93007 7.79594   4.12982  0.638 98.48234  ? 32  LYS   A HZ1  1 
ATOM   506  H HZ2  A LYS   A 1 35  ? 25.76556 6.86270   4.88920  0.362 82.54469  ? 32  LYS   A HZ2  1 
ATOM   507  H HZ2  B LYS   A 1 35  ? 26.46414 6.42470   4.16059  0.638 98.48234  ? 32  LYS   A HZ2  1 
ATOM   508  H HZ3  A LYS   A 1 35  ? 25.69370 8.22791   5.36812  0.362 82.54469  ? 32  LYS   A HZ3  1 
ATOM   509  H HZ3  B LYS   A 1 35  ? 25.78317 7.43868   4.93934  0.638 98.48234  ? 32  LYS   A HZ3  1 
ATOM   510  N N    . VAL   A 1 36  ? 29.84585 3.64942   10.64154 1.000 25.21599  ? 33  VAL   A N    1 
ATOM   511  C CA   . VAL   A 1 36  ? 29.80661 2.35609   11.29869 1.000 20.46184  ? 33  VAL   A CA   1 
ATOM   512  C C    . VAL   A 1 36  ? 28.36901 1.99527   11.63214 1.000 22.92195  ? 33  VAL   A C    1 
ATOM   513  O O    . VAL   A 1 36  ? 27.62565 2.80204   12.20275 1.000 28.95395  ? 33  VAL   A O    1 
ATOM   514  C CB   . VAL   A 1 36  ? 30.66064 2.35655   12.58011 1.000 25.14854  ? 33  VAL   A CB   1 
ATOM   515  C CG1  . VAL   A 1 36  ? 30.58339 1.01286   13.25420 1.000 19.34716  ? 33  VAL   A CG1  1 
ATOM   516  C CG2  . VAL   A 1 36  ? 32.08364 2.75537   12.25943 1.000 24.04919  ? 33  VAL   A CG2  1 
ATOM   517  H H    . VAL   A 1 36  ? 29.70229 4.30480   11.17956 1.000 30.27785  ? 33  VAL   A H    1 
ATOM   518  H HA   . VAL   A 1 36  ? 30.14742 1.69095   10.68035 1.000 24.57287  ? 33  VAL   A HA   1 
ATOM   519  H HB   . VAL   A 1 36  ? 30.31572 3.01160   13.20688 1.000 30.19690  ? 33  VAL   A HB   1 
ATOM   520  H HG11 . VAL   A 1 36  ? 31.23445 0.98204   13.97259 1.000 23.23525  ? 33  VAL   A HG11 1 
ATOM   521  H HG12 . VAL   A 1 36  ? 29.69015 0.88983   13.61181 1.000 23.23525  ? 33  VAL   A HG12 1 
ATOM   522  H HG13 . VAL   A 1 36  ? 30.77696 0.32100   12.60247 1.000 23.23525  ? 33  VAL   A HG13 1 
ATOM   523  H HG21 . VAL   A 1 36  ? 32.62487 2.66482   13.05929 1.000 28.87769  ? 33  VAL   A HG21 1 
ATOM   524  H HG22 . VAL   A 1 36  ? 32.42483 2.17435   11.56164 1.000 28.87769  ? 33  VAL   A HG22 1 
ATOM   525  H HG23 . VAL   A 1 36  ? 32.09272 3.67679   11.95646 1.000 28.87769  ? 33  VAL   A HG23 1 
ATOM   526  N N    . THR   A 1 37  ? 27.99875 0.76269   11.32257 1.000 21.57019  ? 34  THR   A N    1 
ATOM   527  C CA   . THR   A 1 37  ? 26.71090 0.20745   11.69427 1.000 24.62127  ? 34  THR   A CA   1 
ATOM   528  C C    . THR   A 1 37  ? 26.94929 -0.93894  12.65489 1.000 23.84437  ? 34  THR   A C    1 
ATOM   529  O O    . THR   A 1 37  ? 27.55231 -1.94925  12.28142 1.000 26.85752  ? 34  THR   A O    1 
ATOM   530  C CB   . THR   A 1 37  ? 25.93440 -0.27555  10.46528 1.000 24.42239  ? 34  THR   A CB   1 
ATOM   531  O OG1  . THR   A 1 37  ? 25.73352 0.82451   9.56532  1.000 33.12196  ? 34  THR   A OG1  1 
ATOM   532  C CG2  . THR   A 1 37  ? 24.58393 -0.84811  10.88763 1.000 28.31642  ? 34  THR   A CG2  1 
ATOM   533  H H    . THR   A 1 37  ? 28.49316 0.21267   10.88367 1.000 25.90289  ? 34  THR   A H    1 
ATOM   534  H HA   . THR   A 1 37  ? 26.17949 0.88687   12.13799 1.000 29.56417  ? 34  THR   A HA   1 
ATOM   535  H HB   . THR   A 1 37  ? 26.43314 -0.97273  10.01129 1.000 29.32552  ? 34  THR   A HB   1 
ATOM   536  H HG1  . THR   A 1 37  ? 25.36705 0.55482   8.85923  1.000 39.76501  ? 34  THR   A HG1  1 
ATOM   537  H HG21 . THR   A 1 37  ? 24.03932 -1.02550  10.10480 1.000 33.99836  ? 34  THR   A HG21 1 
ATOM   538  H HG22 . THR   A 1 37  ? 24.71277 -1.67639  11.37574 1.000 33.99836  ? 34  THR   A HG22 1 
ATOM   539  H HG23 . THR   A 1 37  ? 24.11916 -0.21578  11.45775 1.000 33.99836  ? 34  THR   A HG23 1 
ATOM   540  N N    . VAL   A 1 38  ? 26.48668 -0.77327  13.88551 1.000 18.91655  ? 35  VAL   A N    1 
ATOM   541  C CA   . VAL   A 1 38  ? 26.49541 -1.84185  14.87471 1.000 21.92568  ? 35  VAL   A CA   1 
ATOM   542  C C    . VAL   A 1 38  ? 25.18215 -2.59778  14.72066 1.000 28.32961  ? 35  VAL   A C    1 
ATOM   543  O O    . VAL   A 1 38  ? 24.10539 -2.06958  15.01733 1.000 28.39948  ? 35  VAL   A O    1 
ATOM   544  C CB   . VAL   A 1 38  ? 26.67600 -1.30477  16.29665 1.000 25.68375  ? 35  VAL   A CB   1 
ATOM   545  C CG1  . VAL   A 1 38  ? 26.67315 -2.44971  17.27895 1.000 30.71385  ? 35  VAL   A CG1  1 
ATOM   546  C CG2  . VAL   A 1 38  ? 27.98726 -0.52462  16.42224 1.000 23.60965  ? 35  VAL   A CG2  1 
ATOM   547  H H    . VAL   A 1 38  ? 26.15548 -0.03561  14.17838 1.000 22.71851  ? 35  VAL   A H    1 
ATOM   548  H HA   . VAL   A 1 38  ? 27.23164 -2.44773  14.69646 1.000 26.32947  ? 35  VAL   A HA   1 
ATOM   549  H HB   . VAL   A 1 38  ? 25.94195 -0.70359  16.49829 1.000 30.83915  ? 35  VAL   A HB   1 
ATOM   550  H HG11 . VAL   A 1 38  ? 26.93167 -2.11689  18.15262 1.000 36.87528  ? 35  VAL   A HG11 1 
ATOM   551  H HG12 . VAL   A 1 38  ? 25.78107 -2.82842  17.31995 1.000 36.87528  ? 35  VAL   A HG12 1 
ATOM   552  H HG13 . VAL   A 1 38  ? 27.30491 -3.12285  16.98119 1.000 36.87528  ? 35  VAL   A HG13 1 
ATOM   553  H HG21 . VAL   A 1 38  ? 28.04358 -0.14283  17.31216 1.000 28.35024  ? 35  VAL   A HG21 1 
ATOM   554  H HG22 . VAL   A 1 38  ? 28.73043 -1.13023  16.27448 1.000 28.35024  ? 35  VAL   A HG22 1 
ATOM   555  H HG23 . VAL   A 1 38  ? 27.99921 0.18197   15.75780 1.000 28.35024  ? 35  VAL   A HG23 1 
ATOM   556  N N    . ALA   A 1 39  ? 25.27501 -3.83066  14.24388 1.000 25.61252  ? 36  ALA   A N    1 
ATOM   557  C CA   . ALA   A 1 39  ? 24.12347 -4.63413  13.88637 1.000 22.99634  ? 36  ALA   A CA   1 
ATOM   558  C C    . ALA   A 1 39  ? 23.97539 -5.78467  14.86125 1.000 27.15847  ? 36  ALA   A C    1 
ATOM   559  O O    . ALA   A 1 39  ? 24.91381 -6.56375  15.06484 1.000 25.88637  ? 36  ALA   A O    1 
ATOM   560  C CB   . ALA   A 1 39  ? 24.26552 -5.17906  12.46653 1.000 24.83906  ? 36  ALA   A CB   1 
ATOM   561  H H    . ALA   A 1 39  ? 26.02295 -4.23515  14.11514 1.000 30.75368  ? 36  ALA   A H    1 
ATOM   562  H HA   . ALA   A 1 39  ? 23.32461 -4.08626  13.93697 1.000 27.61427  ? 36  ALA   A HA   1 
ATOM   563  H HB1  . ALA   A 1 39  ? 23.46888 -5.68446  12.24107 1.000 29.82552  ? 36  ALA   A HB1  1 
ATOM   564  H HB2  . ALA   A 1 39  ? 24.37071 -4.43589  11.85210 1.000 29.82552  ? 36  ALA   A HB2  1 
ATOM   565  H HB3  . ALA   A 1 39  ? 25.04509 -5.75483  12.42577 1.000 29.82552  ? 36  ALA   A HB3  1 
ATOM   566  N N    . GLY   A 1 40  ? 22.79000 -5.89057  15.45575 1.000 23.44266  ? 37  GLY   A N    1 
ATOM   567  C CA   . GLY   A 1 40  ? 22.50853 -6.98346  16.35793 1.000 27.12419  ? 37  GLY   A CA   1 
ATOM   568  C C    . GLY   A 1 40  ? 22.22649 -8.24761  15.57563 1.000 27.60017  ? 37  GLY   A C    1 
ATOM   569  O O    . GLY   A 1 40  ? 21.38092 -8.26216  14.67448 1.000 30.96239  ? 37  GLY   A O    1 
ATOM   570  H H    . GLY   A 1 40  ? 22.13772 -5.34032  15.34919 1.000 28.14984  ? 37  GLY   A H    1 
ATOM   571  H HA2  . GLY   A 1 40  ? 23.27026 -7.13631  16.93870 1.000 32.56768  ? 37  GLY   A HA2  1 
ATOM   572  H HA3  . GLY   A 1 40  ? 21.73416 -6.77093  16.90207 1.000 32.56768  ? 37  GLY   A HA3  1 
ATOM   573  N N    . LEU   A 1 41  ? 22.94661 -9.31639  15.91853 1.000 26.75562  ? 38  LEU   A N    1 
ATOM   574  C CA   . LEU   A 1 41  ? 22.72043 -10.60996 15.28002 1.000 35.81763  ? 38  LEU   A CA   1 
ATOM   575  C C    . LEU   A 1 41  ? 21.26766 -11.05697 15.40817 1.000 31.57947  ? 38  LEU   A C    1 
ATOM   576  O O    . LEU   A 1 41  ? 20.67915 -11.56733 14.44569 1.000 37.09433  ? 38  LEU   A O    1 
ATOM   577  C CB   . LEU   A 1 41  ? 23.65511 -11.65208 15.89706 1.000 34.95233  ? 38  LEU   A CB   1 
ATOM   578  C CG   . LEU   A 1 41  ? 23.62258 -13.07152 15.33848 1.000 39.36675  ? 38  LEU   A CG   1 
ATOM   579  C CD1  . LEU   A 1 41  ? 24.00341 -13.06450 13.87146 1.000 39.43491  ? 38  LEU   A CD1  1 
ATOM   580  C CD2  . LEU   A 1 41  ? 24.55782 -13.96265 16.12731 1.000 35.53110  ? 38  LEU   A CD2  1 
ATOM   581  H H    . LEU   A 1 41  ? 23.56748 -9.31888  16.51360 1.000 32.12540  ? 38  LEU   A H    1 
ATOM   582  H HA   . LEU   A 1 41  ? 22.92055 -10.53139 14.33414 1.000 42.99981  ? 38  LEU   A HA   1 
ATOM   583  H HB2  . LEU   A 1 41  ? 24.56428 -11.33190 15.78848 1.000 41.96145  ? 38  LEU   A HB2  1 
ATOM   584  H HB3  . LEU   A 1 41  ? 23.43762 -11.71984 16.83993 1.000 41.96145  ? 38  LEU   A HB3  1 
ATOM   585  H HG   . LEU   A 1 41  ? 22.72464 -13.43011 15.41603 1.000 47.25875  ? 38  LEU   A HG   1 
ATOM   586  H HD11 . LEU   A 1 41  ? 23.19938 -12.97133 13.33691 1.000 47.34054  ? 38  LEU   A HD11 1 
ATOM   587  H HD12 . LEU   A 1 41  ? 24.60041 -12.31860 13.70373 1.000 47.34054  ? 38  LEU   A HD12 1 
ATOM   588  H HD13 . LEU   A 1 41  ? 24.44851 -13.89917 13.65673 1.000 47.34054  ? 38  LEU   A HD13 1 
ATOM   589  H HD21 . LEU   A 1 41  ? 24.52919 -14.85814 15.75558 1.000 42.65597  ? 38  LEU   A HD21 1 
ATOM   590  H HD22 . LEU   A 1 41  ? 25.45852 -13.60781 16.06626 1.000 42.65597  ? 38  LEU   A HD22 1 
ATOM   591  H HD23 . LEU   A 1 41  ? 24.27114 -13.97979 17.05381 1.000 42.65597  ? 38  LEU   A HD23 1 
ATOM   592  N N    . ALA   A 1 42  ? 20.66813 -10.86604 16.57964 1.000 37.21842  ? 39  ALA   A N    1 
ATOM   593  C CA   . ALA   A 1 42  ? 19.34615 -11.40835 16.86633 1.000 47.59742  ? 39  ALA   A CA   1 
ATOM   594  C C    . ALA   A 1 42  ? 18.20842 -10.42795 16.60415 1.000 35.92126  ? 39  ALA   A C    1 
ATOM   595  O O    . ALA   A 1 42  ? 17.04269 -10.79662 16.77144 1.000 47.68948  ? 39  ALA   A O    1 
ATOM   596  C CB   . ALA   A 1 42  ? 19.28523 -11.87035 18.32442 1.000 47.53327  ? 39  ALA   A CB   1 
ATOM   597  H H    . ALA   A 1 42  ? 21.01133 -10.42097 17.23058 1.000 44.68076  ? 39  ALA   A H    1 
ATOM   598  H HA   . ALA   A 1 42  ? 19.20350 -12.17461 16.28893 1.000 57.13556  ? 39  ALA   A HA   1 
ATOM   599  H HB1  . ALA   A 1 42  ? 18.40289 -12.23062 18.50494 1.000 57.05858  ? 39  ALA   A HB1  1 
ATOM   600  H HB2  . ALA   A 1 42  ? 19.95755 -12.55482 18.46718 1.000 57.05858  ? 39  ALA   A HB2  1 
ATOM   601  H HB3  . ALA   A 1 42  ? 19.45753 -11.11155 18.90359 1.000 57.05858  ? 39  ALA   A HB3  1 
ATOM   602  N N    . GLY   A 1 43  ? 18.50892 -9.21047  16.19962 1.000 35.73122  ? 40  GLY   A N    1 
ATOM   603  C CA   . GLY   A 1 43  ? 17.51681 -8.18574  15.99832 1.000 34.83863  ? 40  GLY   A CA   1 
ATOM   604  C C    . GLY   A 1 43  ? 18.02117 -6.86269  16.51398 1.000 33.46830  ? 40  GLY   A C    1 
ATOM   605  O O    . GLY   A 1 43  ? 19.20130 -6.70267  16.81807 1.000 37.66394  ? 40  GLY   A O    1 
ATOM   606  H H    . GLY   A 1 43  ? 19.31016 -8.94801  16.03008 1.000 42.89612  ? 40  GLY   A H    1 
ATOM   607  H HA2  . GLY   A 1 43  ? 17.31885 -8.09947  15.05267 1.000 41.82501  ? 40  GLY   A HA2  1 
ATOM   608  H HA3  . GLY   A 1 43  ? 16.70245 -8.41752  16.47159 1.000 41.82501  ? 40  GLY   A HA3  1 
ATOM   609  N N    . LYS   A 1 44  ? 17.09195 -5.91140  16.62598 1.000 35.71113  ? 41  LYS   A N    1 
ATOM   610  C CA   . LYS   A 1 44  ? 17.35407 -4.54414  17.06938 1.000 40.82903  ? 41  LYS   A CA   1 
ATOM   611  C C    . LYS   A 1 44  ? 17.42376 -4.41607  18.58762 1.000 39.58186  ? 41  LYS   A C    1 
ATOM   612  O O    . LYS   A 1 44  ? 17.76090 -3.33915  19.08784 1.000 40.12967  ? 41  LYS   A O    1 
ATOM   613  C CB   . LYS   A 1 44  ? 16.25116 -3.63394  16.49284 1.000 47.83816  ? 41  LYS   A CB   1 
ATOM   614  C CG   . LYS   A 1 44  ? 16.27902 -2.15575  16.89189 1.000 111.04552 ? 41  LYS   A CG   1 
ATOM   615  C CD   . LYS   A 1 44  ? 16.97461 -1.28230  15.85102 1.000 87.96854  ? 41  LYS   A CD   1 
ATOM   616  C CE   . LYS   A 1 44  ? 16.53865 0.18000   15.96691 1.000 91.75630  ? 41  LYS   A CE   1 
ATOM   617  N NZ   . LYS   A 1 44  ? 15.07261 0.36058   15.72067 1.000 119.35452 ? 41  LYS   A NZ   1 
ATOM   618  H H    . LYS   A 1 44  ? 16.26182 -6.04018  16.44183 1.000 42.87201  ? 41  LYS   A H    1 
ATOM   619  H HA   . LYS   A 1 44  ? 18.21042 -4.23818  16.73183 1.000 49.01349  ? 41  LYS   A HA   1 
ATOM   620  H HB2  . LYS   A 1 44  ? 16.31516 -3.66474  15.52545 1.000 57.42444  ? 41  LYS   A HB2  1 
ATOM   621  H HB3  . LYS   A 1 44  ? 15.39417 -3.98607  16.78001 1.000 57.42444  ? 41  LYS   A HB3  1 
ATOM   622  H HG2  . LYS   A 1 44  ? 15.36846 -1.83673  16.99187 1.000 133.27328 ? 41  LYS   A HG2  1 
ATOM   623  H HG3  . LYS   A 1 44  ? 16.75725 -2.06234  17.73063 1.000 133.27328 ? 41  LYS   A HG3  1 
ATOM   624  H HD2  . LYS   A 1 44  ? 17.93444 -1.32604  15.98412 1.000 105.58090 ? 41  LYS   A HD2  1 
ATOM   625  H HD3  . LYS   A 1 44  ? 16.74812 -1.59876  14.96250 1.000 105.58090 ? 41  LYS   A HD3  1 
ATOM   626  H HE2  . LYS   A 1 44  ? 16.73540 0.50009   16.86119 1.000 110.12622 ? 41  LYS   A HE2  1 
ATOM   627  H HE3  . LYS   A 1 44  ? 17.02125 0.70810   15.31185 1.000 110.12622 ? 41  LYS   A HE3  1 
ATOM   628  H HZ1  . LYS   A 1 44  ? 14.88424 1.22514   15.62501 1.000 143.24408 ? 41  LYS   A HZ1  1 
ATOM   629  H HZ2  . LYS   A 1 44  ? 14.83292 -0.07092  14.98010 1.000 143.24408 ? 41  LYS   A HZ2  1 
ATOM   630  H HZ3  . LYS   A 1 44  ? 14.60667 0.03763   16.40675 1.000 143.24408 ? 41  LYS   A HZ3  1 
ATOM   631  N N    . ASP   A 1 45  ? 17.15440 -5.48253  19.33124 1.000 36.35807  ? 42  ASP   A N    1 
ATOM   632  C CA   . ASP   A 1 45  ? 17.02142 -5.37018  20.77451 1.000 27.20067  ? 42  ASP   A CA   1 
ATOM   633  C C    . ASP   A 1 45  ? 18.38255 -5.23368  21.45173 1.000 41.49794  ? 42  ASP   A C    1 
ATOM   634  O O    . ASP   A 1 45  ? 19.40919 -5.64558  20.91102 1.000 26.31953  ? 42  ASP   A O    1 
ATOM   635  C CB   . ASP   A 1 45  ? 16.29269 -6.58899  21.33626 1.000 58.03392  ? 42  ASP   A CB   1 
ATOM   636  C CG   . ASP   A 1 45  ? 14.82684 -6.63669  20.93383 1.000 57.46298  ? 42  ASP   A CG   1 
ATOM   637  O OD1  . ASP   A 1 45  ? 14.19978 -5.56360  20.78230 1.000 65.50268  ? 42  ASP   A OD1  1 
ATOM   638  O OD2  . ASP   A 1 45  ? 14.30542 -7.75783  20.77278 1.000 62.53941  ? 42  ASP   A OD2  1 
ATOM   639  H H    . ASP   A 1 45  ? 17.04487 -6.27821  19.02384 1.000 43.64834  ? 42  ASP   A H    1 
ATOM   640  H HA   . ASP   A 1 45  ? 16.50208 -4.57647  20.97753 1.000 32.65946  ? 42  ASP   A HA   1 
ATOM   641  H HB2  . ASP   A 1 45  ? 16.72089 -7.39369  21.00460 1.000 69.65936  ? 42  ASP   A HB2  1 
ATOM   642  H HB3  . ASP   A 1 45  ? 16.33693 -6.56478  22.30495 1.000 69.65936  ? 42  ASP   A HB3  1 
ATOM   643  N N    . PRO   A 1 46  ? 18.40828 -4.66500  22.65298 1.000 33.06716  ? 43  PRO   A N    1 
ATOM   644  C CA   . PRO   A 1 46  ? 19.68439 -4.48532  23.35753 1.000 31.97255  ? 43  PRO   A CA   1 
ATOM   645  C C    . PRO   A 1 46  ? 20.38569 -5.80988  23.59804 1.000 32.75248  ? 43  PRO   A C    1 
ATOM   646  O O    . PRO   A 1 46  ? 19.75549 -6.82499  23.90242 1.000 31.97842  ? 43  PRO   A O    1 
ATOM   647  C CB   . PRO   A 1 46  ? 19.27412 -3.82848  24.67954 1.000 32.92833  ? 43  PRO   A CB   1 
ATOM   648  C CG   . PRO   A 1 46  ? 17.90745 -3.28908  24.43971 1.000 40.23643  ? 43  PRO   A CG   1 
ATOM   649  C CD   . PRO   A 1 46  ? 17.26469 -4.20308  23.45516 1.000 47.05739  ? 43  PRO   A CD   1 
ATOM   650  H HA   . PRO   A 1 46  ? 20.26557 -3.89267  22.85565 1.000 38.38572  ? 43  PRO   A HA   1 
ATOM   651  H HB2  . PRO   A 1 46  ? 19.26562 -4.49117  25.38783 1.000 39.53266  ? 43  PRO   A HB2  1 
ATOM   652  H HB3  . PRO   A 1 46  ? 19.89418 -3.11572  24.89950 1.000 39.53266  ? 43  PRO   A HB3  1 
ATOM   653  H HG2  . PRO   A 1 46  ? 17.41051 -3.27971  25.27270 1.000 48.30237  ? 43  PRO   A HG2  1 
ATOM   654  H HG3  . PRO   A 1 46  ? 17.97076 -2.39006  24.08104 1.000 48.30237  ? 43  PRO   A HG3  1 
ATOM   655  H HD2  . PRO   A 1 46  ? 16.83044 -4.94632  23.90229 1.000 56.48752  ? 43  PRO   A HD2  1 
ATOM   656  H HD3  . PRO   A 1 46  ? 16.62355 -3.72652  22.90496 1.000 56.48752  ? 43  PRO   A HD3  1 
ATOM   657  N N    . VAL   A 1 47  ? 21.70929 -5.76745  23.51763 1.000 26.58481  ? 44  VAL   A N    1 
ATOM   658  C CA   . VAL   A 1 47  ? 22.55898 -6.94281  23.59105 1.000 24.55651  ? 44  VAL   A CA   1 
ATOM   659  C C    . VAL   A 1 47  ? 23.32956 -6.92305  24.90266 1.000 24.19578  ? 44  VAL   A C    1 
ATOM   660  O O    . VAL   A 1 47  ? 24.01632 -5.94404  25.22074 1.000 21.89397  ? 44  VAL   A O    1 
ATOM   661  C CB   . VAL   A 1 47  ? 23.51611 -6.98830  22.39029 1.000 28.60629  ? 44  VAL   A CB   1 
ATOM   662  C CG1  . VAL   A 1 47  ? 24.45861 -8.15539  22.50508 1.000 29.63923  ? 44  VAL   A CG1  1 
ATOM   663  C CG2  . VAL   A 1 47  ? 22.72528 -7.05770  21.09491 1.000 29.56415  ? 44  VAL   A CG2  1 
ATOM   664  H H    . VAL   A 1 47  ? 22.15374 -5.03821  23.41630 1.000 31.92042  ? 44  VAL   A H    1 
ATOM   665  H HA   . VAL   A 1 47  ? 22.00684 -7.74033  23.59166 1.000 29.48647  ? 44  VAL   A HA   1 
ATOM   666  H HB   . VAL   A 1 47  ? 24.04963 -6.17828  22.37940 1.000 34.34620  ? 44  VAL   A HB   1 
ATOM   667  H HG11 . VAL   A 1 47  ? 24.83152 -8.34737  21.63044 1.000 35.58574  ? 44  VAL   A HG11 1 
ATOM   668  H HG12 . VAL   A 1 47  ? 25.16916 -7.92772  23.12490 1.000 35.58574  ? 44  VAL   A HG12 1 
ATOM   669  H HG13 . VAL   A 1 47  ? 23.96865 -8.92601  22.83217 1.000 35.58574  ? 44  VAL   A HG13 1 
ATOM   670  H HG21 . VAL   A 1 47  ? 23.33657 -7.22322  20.36019 1.000 35.49564  ? 44  VAL   A HG21 1 
ATOM   671  H HG22 . VAL   A 1 47  ? 22.07989 -7.77916  21.15718 1.000 35.49564  ? 44  VAL   A HG22 1 
ATOM   672  H HG23 . VAL   A 1 47  ? 22.26621 -6.21399  20.95959 1.000 35.49564  ? 44  VAL   A HG23 1 
ATOM   673  N N    . GLN   A 1 48  ? 23.22615 -8.01065  25.65345 1.000 20.90543  ? 45  GLN   A N    1 
ATOM   674  C CA   . GLN   A 1 48  ? 23.97489 -8.18370  26.89213 1.000 20.38821  ? 45  GLN   A CA   1 
ATOM   675  C C    . GLN   A 1 48  ? 25.33987 -8.77310  26.55865 1.000 28.50482  ? 45  GLN   A C    1 
ATOM   676  O O    . GLN   A 1 48  ? 25.43812 -9.91680  26.10959 1.000 26.24196  ? 45  GLN   A O    1 
ATOM   677  C CB   . GLN   A 1 48  ? 23.20734 -9.07416  27.86287 1.000 34.57554  ? 45  GLN   A CB   1 
ATOM   678  C CG   . GLN   A 1 48  ? 23.90009 -9.27609  29.18822 1.000 47.80708  ? 45  GLN   A CG   1 
ATOM   679  C CD   . GLN   A 1 48  ? 23.09657 -10.14542 30.13960 1.000 56.31787  ? 45  GLN   A CD   1 
ATOM   680  O OE1  . GLN   A 1 48  ? 22.47177 -11.12495 29.73181 1.000 50.22353  ? 45  GLN   A OE1  1 
ATOM   681  N NE2  . GLN   A 1 48  ? 23.10285 -9.78155  31.41398 1.000 75.66349  ? 45  GLN   A NE2  1 
ATOM   682  H H    . GLN   A 1 48  ? 22.71785 -8.67780  25.46333 1.000 25.10517  ? 45  GLN   A H    1 
ATOM   683  H HA   . GLN   A 1 48  ? 24.10946 -7.32039  27.31342 1.000 24.48450  ? 45  GLN   A HA   1 
ATOM   684  H HB2  . GLN   A 1 48  ? 22.34377 -8.66936  28.03978 1.000 41.50930  ? 45  GLN   A HB2  1 
ATOM   685  H HB3  . GLN   A 1 48  ? 23.08770 -9.94668  27.45631 1.000 41.50930  ? 45  GLN   A HB3  1 
ATOM   686  H HG2  . GLN   A 1 48  ? 24.75535 -9.70772  29.03612 1.000 57.38716  ? 45  GLN   A HG2  1 
ATOM   687  H HG3  . GLN   A 1 48  ? 24.03441 -8.41308  29.61021 1.000 57.38716  ? 45  GLN   A HG3  1 
ATOM   688  H HE21 . GLN   A 1 48  ? 23.54608 -9.08709  31.66069 1.000 90.81484  ? 45  GLN   A HE21 1 
ATOM   689  H HE22 . GLN   A 1 48  ? 22.66369 -10.23989 31.99420 1.000 90.81484  ? 45  GLN   A HE22 1 
ATOM   690  N N    . CYS   A 1 49  ? 26.39192 -7.99234  26.79353 1.000 23.65883  ? 46  CYS   A N    1 
ATOM   691  C CA   . CYS   A 1 49  ? 27.74108 -8.41605  26.47216 1.000 24.84146  ? 46  CYS   A CA   1 
ATOM   692  C C    . CYS   A 1 49  ? 28.32063 -9.25342  27.61102 1.000 19.98147  ? 46  CYS   A C    1 
ATOM   693  O O    . CYS   A 1 49  ? 27.69591 -9.46674  28.65327 1.000 21.02099  ? 46  CYS   A O    1 
ATOM   694  C CB   . CYS   A 1 49  ? 28.59932 -7.19472  26.16428 1.000 22.31218  ? 46  CYS   A CB   1 
ATOM   695  S SG   . CYS   A 1 49  ? 28.03889 -6.32166  24.68617 1.000 26.17485  ? 46  CYS   A SG   1 
ATOM   696  H H    . CYS   A 1 49  ? 26.34504 -7.20719  27.14131 1.000 28.40925  ? 46  CYS   A H    1 
ATOM   697  H HA   . CYS   A 1 49  ? 27.72312 -8.97876  25.68227 1.000 29.82840  ? 46  CYS   A HA   1 
ATOM   698  H HB2  . CYS   A 1 49  ? 28.55722 -6.57987  26.91334 1.000 26.79328  ? 46  CYS   A HB2  1 
ATOM   699  H HB3  . CYS   A 1 49  ? 29.51542 -7.47862  26.01918 1.000 26.79328  ? 46  CYS   A HB3  1 
ATOM   700  H HG   . CYS   A 1 49  ? 28.78815 -5.41141  24.46243 1.000 31.42847  ? 46  CYS   A HG   1 
ATOM   701  N N    . SER   A 1 50  ? 29.54945 -9.73038  27.40121 1.000 21.96853  ? 47  SER   A N    1 
ATOM   702  C CA   . SER   A 1 50  ? 30.10370 -10.77592 28.25541 1.000 20.23348  ? 47  SER   A CA   1 
ATOM   703  C C    . SER   A 1 50  ? 30.23724 -10.32074 29.69683 1.000 22.71811  ? 47  SER   A C    1 
ATOM   704  O O    . SER   A 1 50  ? 30.09145 -11.13612 30.61302 1.000 18.65159  ? 47  SER   A O    1 
ATOM   705  C CB   . SER   A 1 50  ? 31.46867 -11.22156 27.71676 1.000 23.53762  ? 47  SER   A CB   1 
ATOM   706  O OG   . SER   A 1 50  ? 32.43284 -10.18372 27.81088 1.000 20.35477  ? 47  SER   A OG   1 
ATOM   707  H H    . SER   A 1 50  ? 30.07756 -9.46685  26.77571 1.000 26.38089  ? 47  SER   A H    1 
ATOM   708  H HA   . SER   A 1 50  ? 29.50286 -11.53723 28.23840 1.000 24.29883  ? 47  SER   A HA   1 
ATOM   709  H HB2  . SER   A 1 50  ? 31.77613 -11.98176 28.23489 1.000 28.26380  ? 47  SER   A HB2  1 
ATOM   710  H HB3  . SER   A 1 50  ? 31.37010 -11.47308 26.78514 1.000 28.26380  ? 47  SER   A HB3  1 
ATOM   711  H HG   . SER   A 1 50  ? 32.14058 -9.48607  27.44554 1.000 24.44438  ? 47  SER   A HG   1 
ATOM   712  N N    . ARG   A 1 51  ? 30.53088 -9.04741  29.92117 1.000 20.27438  ? 48  ARG   A N    1 
ATOM   713  C CA   . ARG   A 1 51  ? 30.65101 -8.50655  31.26701 1.000 18.56151  ? 48  ARG   A CA   1 
ATOM   714  C C    . ARG   A 1 51  ? 29.45862 -7.62280  31.62336 1.000 25.22085  ? 48  ARG   A C    1 
ATOM   715  O O    . ARG   A 1 51  ? 29.59369 -6.67399  32.39648 1.000 23.48060  ? 48  ARG   A O    1 
ATOM   716  C CB   . ARG   A 1 51  ? 31.96675 -7.74327  31.42093 1.000 19.55444  ? 48  ARG   A CB   1 
ATOM   717  C CG   . ARG   A 1 51  ? 33.13280 -8.62253  31.85840 1.000 27.50571  ? 48  ARG   A CG   1 
ATOM   718  C CD   . ARG   A 1 51  ? 33.52045 -9.59706  30.77818 1.000 25.79721  ? 48  ARG   A CD   1 
ATOM   719  N NE   . ARG   A 1 51  ? 34.51662 -10.57064 31.20732 1.000 19.85223  ? 48  ARG   A NE   1 
ATOM   720  C CZ   . ARG   A 1 51  ? 35.00540 -11.51862 30.41474 1.000 19.88000  ? 48  ARG   A CZ   1 
ATOM   721  N NH1  . ARG   A 1 51  ? 34.63705 -11.61176 29.14627 1.000 22.03238  ? 48  ARG   A NH1  1 
ATOM   722  N NH2  . ARG   A 1 51  ? 35.86966 -12.39795 30.90969 1.000 32.27275  ? 48  ARG   A NH2  1 
ATOM   723  H H    . ARG   A 1 51  ? 30.66705 -8.46845  29.30000 1.000 24.34792  ? 48  ARG   A H    1 
ATOM   724  H HA   . ARG   A 1 51  ? 30.66710 -9.24066  31.90083 1.000 22.29246  ? 48  ARG   A HA   1 
ATOM   725  H HB2  . ARG   A 1 51  ? 32.19884 -7.34494  30.56749 1.000 23.48398  ? 48  ARG   A HB2  1 
ATOM   726  H HB3  . ARG   A 1 51  ? 31.84990 -7.05038  32.08962 1.000 23.48398  ? 48  ARG   A HB3  1 
ATOM   727  H HG2  . ARG   A 1 51  ? 33.90082 -8.06383  32.05565 1.000 33.02550  ? 48  ARG   A HG2  1 
ATOM   728  H HG3  . ARG   A 1 51  ? 32.87775 -9.12635  32.64707 1.000 33.02550  ? 48  ARG   A HG3  1 
ATOM   729  H HD2  . ARG   A 1 51  ? 32.73040 -10.08465 30.49714 1.000 30.97531  ? 48  ARG   A HD2  1 
ATOM   730  H HD3  . ARG   A 1 51  ? 33.89021 -9.10432  30.02893 1.000 30.97531  ? 48  ARG   A HD3  1 
ATOM   731  H HE   . ARG   A 1 51  ? 34.80349 -10.52935 32.01701 1.000 23.84133  ? 48  ARG   A HE   1 
ATOM   732  H HH11 . ARG   A 1 51  ? 34.07100 -11.05213 28.82068 1.000 26.45752  ? 48  ARG   A HH11 1 
ATOM   733  H HH12 . ARG   A 1 51  ? 34.96386 -12.23188 28.64803 1.000 26.45752  ? 48  ARG   A HH12 1 
ATOM   734  H HH21 . ARG   A 1 51  ? 36.10704 -12.34985 31.73488 1.000 38.74596  ? 48  ARG   A HH21 1 
ATOM   735  H HH22 . ARG   A 1 51  ? 36.19172 -13.01524 30.40488 1.000 38.74596  ? 48  ARG   A HH22 1 
ATOM   736  N N    . ASP   A 1 52  ? 28.29223 -7.91727  31.04167 1.000 19.08844  ? 49  ASP   A N    1 
ATOM   737  C CA   . ASP   A 1 52  ? 26.98635 -7.39033  31.42537 1.000 25.09053  ? 49  ASP   A CA   1 
ATOM   738  C C    . ASP   A 1 52  ? 26.77300 -5.93836  31.03254 1.000 23.70738  ? 49  ASP   A C    1 
ATOM   739  O O    . ASP   A 1 52  ? 25.76627 -5.33707  31.42856 1.000 24.79947  ? 49  ASP   A O    1 
ATOM   740  C CB   . ASP   A 1 52  ? 26.74917 -7.56520  32.92802 1.000 26.29435  ? 49  ASP   A CB   1 
ATOM   741  C CG   . ASP   A 1 52  ? 26.24537 -8.94359  33.26596 1.000 31.94874  ? 49  ASP   A CG   1 
ATOM   742  O OD1  . ASP   A 1 52  ? 25.83786 -9.66065  32.32692 1.000 28.31993  ? 49  ASP   A OD1  1 
ATOM   743  O OD2  . ASP   A 1 52  ? 26.25328 -9.30723  34.45866 1.000 42.28402  ? 49  ASP   A OD2  1 
ATOM   744  H H    . ASP   A 1 52  ? 28.23352 -8.45873  30.37611 1.000 22.92479  ? 49  ASP   A H    1 
ATOM   745  H HA   . ASP   A 1 52  ? 26.31058 -7.89455  30.94579 1.000 30.12729  ? 49  ASP   A HA   1 
ATOM   746  H HB2  . ASP   A 1 52  ? 27.58422 -7.42383  33.40089 1.000 31.57187  ? 49  ASP   A HB2  1 
ATOM   747  H HB3  . ASP   A 1 52  ? 26.08745 -6.92031  33.22324 1.000 31.57187  ? 49  ASP   A HB3  1 
ATOM   748  N N    . VAL   A 1 53  ? 27.67110 -5.35886  30.24153 1.000 23.52708  ? 50  VAL   A N    1 
ATOM   749  C CA   . VAL   A 1 53  ? 27.37622 -4.09175  29.59980 1.000 22.91516  ? 50  VAL   A CA   1 
ATOM   750  C C    . VAL   A 1 53  ? 26.32286 -4.35146  28.53552 1.000 26.42364  ? 50  VAL   A C    1 
ATOM   751  O O    . VAL   A 1 53  ? 26.44001 -5.30333  27.75388 1.000 22.20152  ? 50  VAL   A O    1 
ATOM   752  C CB   . VAL   A 1 53  ? 28.65341 -3.48728  28.99865 1.000 22.78667  ? 50  VAL   A CB   1 
ATOM   753  C CG1  . VAL   A 1 53  ? 28.31883 -2.23588  28.21516 1.000 24.19903  ? 50  VAL   A CG1  1 
ATOM   754  C CG2  . VAL   A 1 53  ? 29.67225 -3.19109  30.09833 1.000 27.25420  ? 50  VAL   A CG2  1 
ATOM   755  H H    . VAL   A 1 53  ? 28.44954 -5.67865  30.06442 1.000 28.25115  ? 50  VAL   A H    1 
ATOM   756  H HA   . VAL   A 1 53  ? 27.02944 -3.45602  30.24517 1.000 27.51684  ? 50  VAL   A HA   1 
ATOM   757  H HB   . VAL   A 1 53  ? 29.05422 -4.12596  28.38846 1.000 27.36266  ? 50  VAL   A HB   1 
ATOM   758  H HG11 . VAL   A 1 53  ? 29.12958 -1.72012  28.08253 1.000 29.05749  ? 50  VAL   A HG11 1 
ATOM   759  H HG12 . VAL   A 1 53  ? 27.94499 -2.49094  27.35721 1.000 29.05749  ? 50  VAL   A HG12 1 
ATOM   760  H HG13 . VAL   A 1 53  ? 27.67256 -1.71342  28.71543 1.000 29.05749  ? 50  VAL   A HG13 1 
ATOM   761  H HG21 . VAL   A 1 53  ? 30.46224 -2.79488  29.69853 1.000 32.72369  ? 50  VAL   A HG21 1 
ATOM   762  H HG22 . VAL   A 1 53  ? 29.27905 -2.57419  30.73529 1.000 32.72369  ? 50  VAL   A HG22 1 
ATOM   763  H HG23 . VAL   A 1 53  ? 29.90713 -4.02057  30.54295 1.000 32.72369  ? 50  VAL   A HG23 1 
ATOM   764  N N    . VAL   A 1 54  ? 25.28764 -3.52443  28.50346 1.000 25.37225  ? 51  VAL   A N    1 
ATOM   765  C CA   . VAL   A 1 54  ? 24.18256 -3.69733  27.56760 1.000 25.44058  ? 51  VAL   A CA   1 
ATOM   766  C C    . VAL   A 1 54  ? 24.25611 -2.59206  26.52138 1.000 27.76993  ? 51  VAL   A C    1 
ATOM   767  O O    . VAL   A 1 54  ? 24.17995 -1.40628  26.85508 1.000 23.52943  ? 51  VAL   A O    1 
ATOM   768  C CB   . VAL   A 1 54  ? 22.82503 -3.68587  28.29153 1.000 26.55768  ? 51  VAL   A CB   1 
ATOM   769  C CG1  . VAL   A 1 54  ? 21.70307 -3.76729  27.27409 1.000 28.68388  ? 51  VAL   A CG1  1 
ATOM   770  C CG2  . VAL   A 1 54  ? 22.74588 -4.81411  29.28666 1.000 29.72877  ? 51  VAL   A CG2  1 
ATOM   771  H H    . VAL   A 1 54  ? 25.20035 -2.84409  29.02222 1.000 30.46535  ? 51  VAL   A H    1 
ATOM   772  H HA   . VAL   A 1 54  ? 24.28407 -4.54711  27.11100 1.000 30.54735  ? 51  VAL   A HA   1 
ATOM   773  H HB   . VAL   A 1 54  ? 22.72673 -2.85744  28.78645 1.000 31.88787  ? 51  VAL   A HB   1 
ATOM   774  H HG11 . VAL   A 1 54  ? 20.87498 -3.97775  27.73331 1.000 34.43931  ? 51  VAL   A HG11 1 
ATOM   775  H HG12 . VAL   A 1 54  ? 21.62311 -2.91227  26.82305 1.000 34.43931  ? 51  VAL   A HG12 1 
ATOM   776  H HG13 . VAL   A 1 54  ? 21.91032 -4.46272  26.63042 1.000 34.43931  ? 51  VAL   A HG13 1 
ATOM   777  H HG21 . VAL   A 1 54  ? 21.87875 -4.79202  29.72081 1.000 35.69318  ? 51  VAL   A HG21 1 
ATOM   778  H HG22 . VAL   A 1 54  ? 22.86034 -5.65623  28.81908 1.000 35.69318  ? 51  VAL   A HG22 1 
ATOM   779  H HG23 . VAL   A 1 54  ? 23.44878 -4.70362  29.94592 1.000 35.69318  ? 51  VAL   A HG23 1 
ATOM   780  N N    . ILE   A 1 55  ? 24.38284 -2.97659  25.25884 1.000 22.06772  ? 52  ILE   A N    1 
ATOM   781  C CA   . ILE   A 1 55  ? 24.55983 -2.03224  24.15899 1.000 19.71339  ? 52  ILE   A CA   1 
ATOM   782  C C    . ILE   A 1 55  ? 23.34796 -2.10870  23.24682 1.000 26.70515  ? 52  ILE   A C    1 
ATOM   783  O O    . ILE   A 1 55  ? 22.86389 -3.20023  22.93596 1.000 26.55944  ? 52  ILE   A O    1 
ATOM   784  C CB   . ILE   A 1 55  ? 25.86276 -2.34633  23.39394 1.000 27.24093  ? 52  ILE   A CB   1 
ATOM   785  C CG1  . ILE   A 1 55  ? 27.06867 -2.04497  24.28679 1.000 32.09474  ? 52  ILE   A CG1  1 
ATOM   786  C CG2  . ILE   A 1 55  ? 25.92970 -1.57922  22.09973 1.000 27.05001  ? 52  ILE   A CG2  1 
ATOM   787  C CD1  . ILE   A 1 55  ? 28.37745 -2.52379  23.70918 1.000 30.77097  ? 52  ILE   A CD1  1 
ATOM   788  H H    . ILE   A 1 55  ? 24.36940 -3.79857  25.00631 1.000 26.49992  ? 52  ILE   A H    1 
ATOM   789  H HA   . ILE   A 1 55  ? 24.60825 -1.12594  24.50130 1.000 23.67472  ? 52  ILE   A HA   1 
ATOM   790  H HB   . ILE   A 1 55  ? 25.87289 -3.28970  23.16844 1.000 32.70777  ? 52  ILE   A HB   1 
ATOM   791  H HG12 . ILE   A 1 55  ? 27.13269 -1.08537  24.41315 1.000 38.53234  ? 52  ILE   A HG12 1 
ATOM   792  H HG13 . ILE   A 1 55  ? 26.94256 -2.48456  25.14222 1.000 38.53234  ? 52  ILE   A HG13 1 
ATOM   793  H HG21 . ILE   A 1 55  ? 26.84150 -1.59641  21.76923 1.000 32.47866  ? 52  ILE   A HG21 1 
ATOM   794  H HG22 . ILE   A 1 55  ? 25.33627 -1.99522  21.45499 1.000 32.47866  ? 52  ILE   A HG22 1 
ATOM   795  H HG23 . ILE   A 1 55  ? 25.65345 -0.66345  22.26077 1.000 32.47866  ? 52  ILE   A HG23 1 
ATOM   796  H HD11 . ILE   A 1 55  ? 29.05133 -2.51843  24.40686 1.000 36.94382  ? 52  ILE   A HD11 1 
ATOM   797  H HD12 . ILE   A 1 55  ? 28.26148 -3.42445  23.36822 1.000 36.94382  ? 52  ILE   A HD12 1 
ATOM   798  H HD13 . ILE   A 1 55  ? 28.64147 -1.92918  22.98971 1.000 36.94382  ? 52  ILE   A HD13 1 
ATOM   799  N N    . CYS   A 1 56  ? 22.84481 -0.94654  22.83274 1.000 23.47760  ? 53  CYS   A N    1 
ATOM   800  C CA   . CYS   A 1 56  ? 21.75845 -0.90152  21.86611 1.000 19.12349  ? 53  CYS   A CA   1 
ATOM   801  C C    . CYS   A 1 56  ? 22.33260 -0.85106  20.46182 1.000 26.44907  ? 53  CYS   A C    1 
ATOM   802  O O    . CYS   A 1 56  ? 23.05823 0.09773   20.13477 1.000 25.50679  ? 53  CYS   A O    1 
ATOM   803  C CB   . CYS   A 1 56  ? 20.86730 0.30449   22.08694 1.000 28.61767  ? 53  CYS   A CB   1 
ATOM   804  S SG   . CYS   A 1 56  ? 19.95636 0.23162   23.60752 1.000 44.13066  ? 53  CYS   A SG   1 
ATOM   805  H H    . CYS   A 1 56  ? 23.11671 -0.17489  23.09773 1.000 28.19178  ? 53  CYS   A H    1 
ATOM   806  H HA   . CYS   A 1 56  ? 21.21711 -1.70056  21.96299 1.000 22.96684  ? 53  CYS   A HA   1 
ATOM   807  H HB2  . CYS   A 1 56  ? 21.41842 1.10247   22.10700 1.000 34.35986  ? 53  CYS   A HB2  1 
ATOM   808  H HB3  . CYS   A 1 56  ? 20.22885 0.36046   21.35882 1.000 34.35986  ? 53  CYS   A HB3  1 
ATOM   809  H HG   . CYS   A 1 56  ? 19.21097 1.17048   23.66178 1.000 52.97545  ? 53  CYS   A HG   1 
ATOM   810  N N    . PRO   A 1 57  ? 22.04678 -1.82837  19.61004 1.000 25.35651  ? 54  PRO   A N    1 
ATOM   811  C CA   . PRO   A 1 57  ? 22.59037 -1.79083  18.24937 1.000 19.69615  ? 54  PRO   A CA   1 
ATOM   812  C C    . PRO   A 1 57  ? 21.88307 -0.73751  17.41598 1.000 21.82610  ? 54  PRO   A C    1 
ATOM   813  O O    . PRO   A 1 57  ? 20.80736 -0.24312  17.75758 1.000 25.32729  ? 54  PRO   A O    1 
ATOM   814  C CB   . PRO   A 1 57  ? 22.34770 -3.21075  17.71999 1.000 28.55931  ? 54  PRO   A CB   1 
ATOM   815  C CG   . PRO   A 1 57  ? 21.22351 -3.73295  18.51071 1.000 33.44387  ? 54  PRO   A CG   1 
ATOM   816  C CD   . PRO   A 1 57  ? 21.29516 -3.07324  19.87884 1.000 24.81957  ? 54  PRO   A CD   1 
ATOM   817  H HA   . PRO   A 1 57  ? 23.54524 -1.62014  18.24986 1.000 23.65404  ? 54  PRO   A HA   1 
ATOM   818  H HB2  . PRO   A 1 57  ? 22.12119 -3.17611  16.77745 1.000 34.28983  ? 54  PRO   A HB2  1 
ATOM   819  H HB3  . PRO   A 1 57  ? 23.14285 -3.75076  17.85047 1.000 34.28983  ? 54  PRO   A HB3  1 
ATOM   820  H HG2  . PRO   A 1 57  ? 20.38867 -3.50985  18.07008 1.000 40.15130  ? 54  PRO   A HG2  1 
ATOM   821  H HG3  . PRO   A 1 57  ? 21.30786 -4.69570  18.59377 1.000 40.15130  ? 54  PRO   A HG3  1 
ATOM   822  H HD2  . PRO   A 1 57  ? 20.40692 -2.87565  20.21485 1.000 29.80214  ? 54  PRO   A HD2  1 
ATOM   823  H HD3  . PRO   A 1 57  ? 21.77107 -3.63558  20.50985 1.000 29.80214  ? 54  PRO   A HD3  1 
ATOM   824  N N    . ASP   A 1 58  ? 22.54083 -0.35530  16.32887 1.000 21.53299  ? 55  ASP   A N    1 
ATOM   825  C CA   . ASP   A 1 58  ? 21.96491 0.61950   15.41825 1.000 23.85300  ? 55  ASP   A CA   1 
ATOM   826  C C    . ASP   A 1 58  ? 20.86897 0.00342   14.55999 1.000 29.16244  ? 55  ASP   A C    1 
ATOM   827  O O    . ASP   A 1 58  ? 19.95713 0.70901   14.11518 1.000 30.61370  ? 55  ASP   A O    1 
ATOM   828  C CB   . ASP   A 1 58  ? 23.03259 1.21225   14.50080 1.000 23.56285  ? 55  ASP   A CB   1 
ATOM   829  C CG   . ASP   A 1 58  ? 24.13904 1.92288   15.25917 1.000 26.32007  ? 55  ASP   A CG   1 
ATOM   830  O OD1  . ASP   A 1 58  ? 23.84553 2.68188   16.20075 1.000 27.87066  ? 55  ASP   A OD1  1 
ATOM   831  O OD2  . ASP   A 1 58  ? 25.31166 1.72960   14.89137 1.000 29.66902  ? 55  ASP   A OD2  1 
ATOM   832  H H    . ASP   A 1 58  ? 23.31731 -0.64403  16.09796 1.000 25.85824  ? 55  ASP   A H    1 
ATOM   833  H HA   . ASP   A 1 58  ? 21.59277 1.34069   15.94957 1.000 28.64226  ? 55  ASP   A HA   1 
ATOM   834  H HB2  . ASP   A 1 58  ? 23.43602 0.49744   13.98390 1.000 28.29408  ? 55  ASP   A HB2  1 
ATOM   835  H HB3  . ASP   A 1 58  ? 22.61574 1.85637   13.90729 1.000 28.29408  ? 55  ASP   A HB3  1 
ATOM   836  N N    . ALA   A 1 59  ? 20.95181 -1.30051  14.31895 1.000 27.53669  ? 56  ALA   A N    1 
ATOM   837  C CA   . ALA   A 1 59  ? 20.03810 -1.98470  13.42217 1.000 31.68281  ? 56  ALA   A CA   1 
ATOM   838  C C    . ALA   A 1 59  ? 20.12109 -3.47992  13.68029 1.000 30.22939  ? 56  ALA   A C    1 
ATOM   839  O O    . ALA   A 1 59  ? 21.05752 -3.97186  14.32225 1.000 31.56954  ? 56  ALA   A O    1 
ATOM   840  C CB   . ALA   A 1 59  ? 20.37113 -1.67775  11.95739 1.000 28.36975  ? 56  ALA   A CB   1 
ATOM   841  H H    A ALA   A 1 59  ? 21.54107 -1.81869  14.67088 0.670 33.06268  ? 56  ALA   A H    1 
ATOM   842  H H    B ALA   A 1 59  ? 21.54107 -1.81869  14.67088 0.330 33.06268  ? 56  ALA   A H    1 
ATOM   843  H HA   . ALA   A 1 59  ? 19.13045 -1.69542  13.60488 1.000 38.03803  ? 56  ALA   A HA   1 
ATOM   844  H HB1  . ALA   A 1 59  ? 19.73176 -2.13164  11.38636 1.000 34.06235  ? 56  ALA   A HB1  1 
ATOM   845  H HB2  . ALA   A 1 59  ? 20.31916 -0.71954  11.81583 1.000 34.06235  ? 56  ALA   A HB2  1 
ATOM   846  H HB3  . ALA   A 1 59  ? 21.26826 -1.99238  11.76488 1.000 34.06235  ? 56  ALA   A HB3  1 
ATOM   847  N N    . SER   A 1 60  ? 19.12321 -4.19304  13.18388 1.000 29.03979  ? 57  SER   A N    1 
ATOM   848  C CA   . SER   A 1 60  ? 19.22966 -5.64066  13.08590 1.000 36.34489  ? 57  SER   A CA   1 
ATOM   849  C C    . SER   A 1 60  ? 20.19871 -5.99514  11.96161 1.000 25.07222  ? 57  SER   A C    1 
ATOM   850  O O    . SER   A 1 60  ? 20.39388 -5.22784  11.01085 1.000 28.85744  ? 57  SER   A O    1 
ATOM   851  C CB   . SER   A 1 60  ? 17.86408 -6.26567  12.81966 1.000 32.01507  ? 57  SER   A CB   1 
ATOM   852  O OG   . SER   A 1 60  ? 17.44349 -5.96952  11.49938 1.000 37.48780  ? 57  SER   A OG   1 
ATOM   853  H H    . SER   A 1 60  ? 18.37997 -3.86737  12.89903 1.000 34.86640  ? 57  SER   A H    1 
ATOM   854  H HA   . SER   A 1 60  ? 19.55784 -6.01105  13.92017 1.000 43.63252  ? 57  SER   A HA   1 
ATOM   855  H HB2  . SER   A 1 60  ? 17.92745 -7.22774  12.92596 1.000 38.43674  ? 57  SER   A HB2  1 
ATOM   856  H HB3  . SER   A 1 60  ? 17.21983 -5.90415  13.44827 1.000 38.43674  ? 57  SER   A HB3  1 
ATOM   857  H HG   . SER   A 1 60  ? 16.73126 -6.37971  11.32593 1.000 45.00401  ? 57  SER   A HG   1 
ATOM   858  N N    . LEU   A 1 61  ? 20.81981 -7.16915  12.08691 1.000 28.32747  ? 58  LEU   A N    1 
ATOM   859  C CA   . LEU   A 1 61  ? 21.67453 -7.65636  11.01482 1.000 35.42055  ? 58  LEU   A CA   1 
ATOM   860  C C    . LEU   A 1 61  ? 20.87131 -7.84200  9.73199  1.000 38.42006  ? 58  LEU   A C    1 
ATOM   861  O O    . LEU   A 1 61  ? 21.37380 -7.59568  8.63064  1.000 31.09985  ? 58  LEU   A O    1 
ATOM   862  C CB   . LEU   A 1 61  ? 22.32605 -8.97330  11.43515 1.000 26.31811  ? 58  LEU   A CB   1 
ATOM   863  C CG   . LEU   A 1 61  ? 23.35699 -9.55125  10.47136 1.000 26.73989  ? 58  LEU   A CG   1 
ATOM   864  C CD1  . LEU   A 1 61  ? 24.45333 -8.52796  10.20653 1.000 31.76296  ? 58  LEU   A CD1  1 
ATOM   865  C CD2  . LEU   A 1 61  ? 23.94204 -10.84510 11.01244 1.000 36.37537  ? 58  LEU   A CD2  1 
ATOM   866  H H    . LEU   A 1 61  ? 20.76217 -7.68943  12.76925 1.000 34.01162  ? 58  LEU   A H    1 
ATOM   867  H HA   . LEU   A 1 61  ? 22.37925 -7.01212  10.84385 1.000 42.52331  ? 58  LEU   A HA   1 
ATOM   868  H HB2  . LEU   A 1 61  ? 22.77493 -8.83073  12.28313 1.000 31.60039  ? 58  LEU   A HB2  1 
ATOM   869  H HB3  . LEU   A 1 61  ? 21.62612 -9.63698  11.53775 1.000 31.60039  ? 58  LEU   A HB3  1 
ATOM   870  H HG   . LEU   A 1 61  ? 22.92375 -9.75996  9.62896  1.000 32.10652  ? 58  LEU   A HG   1 
ATOM   871  H HD11 . LEU   A 1 61  ? 25.23895 -8.98675  9.87005  1.000 38.13421  ? 58  LEU   A HD11 1 
ATOM   872  H HD12 . LEU   A 1 61  ? 24.13665 -7.88879  9.54920  1.000 38.13421  ? 58  LEU   A HD12 1 
ATOM   873  H HD13 . LEU   A 1 61  ? 24.66644 -8.07173  11.03560 1.000 38.13421  ? 58  LEU   A HD13 1 
ATOM   874  H HD21 . LEU   A 1 61  ? 24.55227 -11.21486 10.35533 1.000 43.66910  ? 58  LEU   A HD21 1 
ATOM   875  H HD22 . LEU   A 1 61  ? 24.41787 -10.65628 11.83635 1.000 43.66910  ? 58  LEU   A HD22 1 
ATOM   876  H HD23 . LEU   A 1 61  ? 23.22074 -11.47083 11.18299 1.000 43.66910  ? 58  LEU   A HD23 1 
ATOM   877  N N    . GLU   A 1 62  ? 19.61556 -8.27894  9.86046  1.000 34.21649  ? 59  GLU   A N    1 
ATOM   878  C CA   . GLU   A 1 62  ? 18.76436 -8.46360  8.69005  1.000 41.67238  ? 59  GLU   A CA   1 
ATOM   879  C C    . GLU   A 1 62  ? 18.63427 -7.17058  7.89751  1.000 29.21723  ? 59  GLU   A C    1 
ATOM   880  O O    . GLU   A 1 62  ? 18.80480 -7.15707  6.67543  1.000 40.94535  ? 59  GLU   A O    1 
ATOM   881  C CB   . GLU   A 1 62  ? 17.39645 -8.96607  9.13755  1.000 56.30563  ? 59  GLU   A CB   1 
ATOM   882  C CG   . GLU   A 1 62  ? 16.56699 -9.55596  8.02717  1.000 87.36150  ? 59  GLU   A CG   1 
ATOM   883  C CD   . GLU   A 1 62  ? 15.14374 -9.82110  8.46209  1.000 116.24922 ? 59  GLU   A CD   1 
ATOM   884  O OE1  . GLU   A 1 62  ? 14.86954 -9.74273  9.68031  1.000 79.18928  ? 59  GLU   A OE1  1 
ATOM   885  O OE2  . GLU   A 1 62  ? 14.30027 -10.09889 7.58407  1.000 136.17788 ? 59  GLU   A OE2  1 
ATOM   886  H H    . GLU   A 1 62  ? 19.23797 -8.47322  10.60832 1.000 41.07844  ? 59  GLU   A H    1 
ATOM   887  H HA   . GLU   A 1 62  ? 19.16062 -9.12873  8.10569  1.000 50.02552  ? 59  GLU   A HA   1 
ATOM   888  H HB2  . GLU   A 1 62  ? 17.52263 -9.65439  9.80926  1.000 67.58541  ? 59  GLU   A HB2  1 
ATOM   889  H HB3  . GLU   A 1 62  ? 16.89996 -8.22249  9.51370  1.000 67.58541  ? 59  GLU   A HB3  1 
ATOM   890  H HG2  . GLU   A 1 62  ? 16.54546 -8.93611  7.28136  1.000 104.85245 ? 59  GLU   A HG2  1 
ATOM   891  H HG3  . GLU   A 1 62  ? 16.96026 -10.39752 7.74787  1.000 104.85245 ? 59  GLU   A HG3  1 
ATOM   892  N N    . ASP   A 1 63  ? 18.34943 -6.06195  8.58181  1.000 36.81947  ? 60  ASP   A N    1 
ATOM   893  C CA   . ASP   A 1 63  ? 18.23245 -4.78429  7.88695  1.000 34.32612  ? 60  ASP   A CA   1 
ATOM   894  C C    . ASP   A 1 63  ? 19.59108 -4.28634  7.40786  1.000 29.96899  ? 60  ASP   A C    1 
ATOM   895  O O    . ASP   A 1 63  ? 19.70462 -3.71824  6.31424  1.000 40.55724  ? 60  ASP   A O    1 
ATOM   896  C CB   . ASP   A 1 63  ? 17.58282 -3.74313  8.79976  1.000 41.97990  ? 60  ASP   A CB   1 
ATOM   897  C CG   . ASP   A 1 63  ? 16.12509 -4.04570  9.08643  1.000 35.60154  ? 60  ASP   A CG   1 
ATOM   898  O OD1  . ASP   A 1 63  ? 15.50982 -4.80696  8.31742  1.000 55.14420  ? 60  ASP   A OD1  1 
ATOM   899  O OD2  . ASP   A 1 63  ? 15.59344 -3.51716  10.08044 1.000 56.24408  ? 60  ASP   A OD2  1 
ATOM   900  H H    A ASP   A 1 63  ? 18.22205 -6.02427  9.43149  0.610 44.20202  ? 60  ASP   A H    1 
ATOM   901  H H    B ASP   A 1 63  ? 18.22205 -6.02427  9.43149  0.390 44.20202  ? 60  ASP   A H    1 
ATOM   902  H HA   . ASP   A 1 63  ? 17.66202 -4.90786  7.11219  1.000 41.20999  ? 60  ASP   A HA   1 
ATOM   903  H HB2  . ASP   A 1 63  ? 18.05744 -3.72360  9.64549  1.000 50.39454  ? 60  ASP   A HB2  1 
ATOM   904  H HB3  . ASP   A 1 63  ? 17.63065 -2.87369  8.37234  1.000 50.39454  ? 60  ASP   A HB3  1 
ATOM   905  N N    . ALA   A 1 64  ? 20.63126 -4.46058  8.22147  1.000 37.71844  ? 61  ALA   A N    1 
ATOM   906  C CA   . ALA   A 1 64  ? 21.94356 -3.97214  7.81966  1.000 30.66302  ? 61  ALA   A CA   1 
ATOM   907  C C    . ALA   A 1 64  ? 22.45939 -4.71779  6.59568  1.000 26.35654  ? 61  ALA   A C    1 
ATOM   908  O O    . ALA   A 1 64  ? 23.15978 -4.13155  5.76396  1.000 35.04064  ? 61  ALA   A O    1 
ATOM   909  C CB   . ALA   A 1 64  ? 22.91986 -4.10190  8.98725  1.000 41.15943  ? 61  ALA   A CB   1 
ATOM   910  H H    . ALA   A 1 64  ? 20.60326 -4.84738  8.98907  1.000 45.28078  ? 61  ALA   A H    1 
ATOM   911  H HA   . ALA   A 1 64  ? 21.88174 -3.03216  7.58832  1.000 36.81428  ? 61  ALA   A HA   1 
ATOM   912  H HB1  . ALA   A 1 64  ? 23.79079 -3.77872  8.70807  1.000 49.40998  ? 61  ALA   A HB1  1 
ATOM   913  H HB2  . ALA   A 1 64  ? 22.59377 -3.57266  9.73188  1.000 49.40998  ? 61  ALA   A HB2  1 
ATOM   914  H HB3  . ALA   A 1 64  ? 22.98056 -5.03478  9.24597  1.000 49.40998  ? 61  ALA   A HB3  1 
ATOM   915  N N    . LYS   A 1 65  ? 22.12510 -6.00349  6.47790  1.000 34.87817  ? 62  LYS   A N    1 
ATOM   916  C CA   . LYS   A 1 65  ? 22.52838 -6.79434  5.31798  1.000 37.75045  ? 62  LYS   A CA   1 
ATOM   917  C C    . LYS   A 1 65  ? 22.07593 -6.14339  4.01707  1.000 49.44698  ? 62  LYS   A C    1 
ATOM   918  O O    . LYS   A 1 65  ? 22.81374 -6.14741  3.02417  1.000 56.75194  ? 62  LYS   A O    1 
ATOM   919  C CB   . LYS   A 1 65  ? 21.94518 -8.20534  5.45367  1.000 47.01442  ? 62  LYS   A CB   1 
ATOM   920  C CG   . LYS   A 1 65  ? 22.23458 -9.16077  4.31366  1.000 76.12244  ? 62  LYS   A CG   1 
ATOM   921  C CD   . LYS   A 1 65  ? 21.13878 -10.23209 4.20353  1.000 121.77215 ? 62  LYS   A CD   1 
ATOM   922  C CE   . LYS   A 1 65  ? 20.99322 -11.06492 5.47788  1.000 81.92655  ? 62  LYS   A CE   1 
ATOM   923  N NZ   . LYS   A 1 65  ? 22.16027 -11.96737 5.69636  1.000 96.86184  ? 62  LYS   A NZ   1 
ATOM   924  H H    . LYS   A 1 65  ? 21.66448 -6.44226  7.05661  1.000 41.87246  ? 62  LYS   A H    1 
ATOM   925  H HA   . LYS   A 1 65  ? 23.49581 -6.85809  5.28783  1.000 45.31920  ? 62  LYS   A HA   1 
ATOM   926  H HB2  . LYS   A 1 65  ? 22.30599 -8.60536  6.26033  1.000 56.43596  ? 62  LYS   A HB2  1 
ATOM   927  H HB3  . LYS   A 1 65  ? 20.98081 -8.12843  5.52421  1.000 56.43596  ? 62  LYS   A HB3  1 
ATOM   928  H HG2  . LYS   A 1 65  ? 22.26728 -8.66782  3.47890  1.000 91.36559  ? 62  LYS   A HG2  1 
ATOM   929  H HG3  . LYS   A 1 65  ? 23.08296 -9.60408  4.47063  1.000 91.36559  ? 62  LYS   A HG3  1 
ATOM   930  H HD2  . LYS   A 1 65  ? 20.28857 -9.79825  4.03083  1.000 146.14524 ? 62  LYS   A HD2  1 
ATOM   931  H HD3  . LYS   A 1 65  ? 21.35766 -10.83469 3.47561  1.000 146.14524 ? 62  LYS   A HD3  1 
ATOM   932  H HE2  . LYS   A 1 65  ? 20.92400 -10.47017 6.24102  1.000 98.33051  ? 62  LYS   A HE2  1 
ATOM   933  H HE3  . LYS   A 1 65  ? 20.19568 -11.61297 5.41098  1.000 98.33051  ? 62  LYS   A HE3  1 
ATOM   934  H HZ1  . LYS   A 1 65  ? 22.05600 -12.42170 6.45453  1.000 116.25286 ? 62  LYS   A HZ1  1 
ATOM   935  H HZ2  . LYS   A 1 65  ? 22.23003 -12.54354 5.02163  1.000 116.25286 ? 62  LYS   A HZ2  1 
ATOM   936  H HZ3  . LYS   A 1 65  ? 22.90939 -11.48947 5.74671  1.000 116.25286 ? 62  LYS   A HZ3  1 
ATOM   937  N N    . LYS   A 1 66  ? 20.87011 -5.56663  4.00867  1.000 52.32123  ? 63  LYS   A N    1 
ATOM   938  C CA   . LYS   A 1 66  ? 20.30654 -5.00658  2.78687  1.000 67.34551  ? 63  LYS   A CA   1 
ATOM   939  C C    . LYS   A 1 66  ? 20.96380 -3.69082  2.39321  1.000 59.23718  ? 63  LYS   A C    1 
ATOM   940  O O    . LYS   A 1 66  ? 20.79829 -3.24627  1.25269  1.000 60.64464  ? 63  LYS   A O    1 
ATOM   941  C CB   . LYS   A 1 66  ? 18.79456 -4.78567  2.94821  1.000 64.11591  ? 63  LYS   A CB   1 
ATOM   942  C CG   . LYS   A 1 66  ? 17.99119 -6.02927  3.34072  1.000 52.87004  ? 63  LYS   A CG   1 
ATOM   943  C CD   . LYS   A 1 66  ? 16.56111 -5.65942  3.75961  1.000 85.47241  ? 63  LYS   A CD   1 
ATOM   944  C CE   . LYS   A 1 66  ? 15.77610 -6.87273  4.24574  1.000 99.34705  ? 63  LYS   A CE   1 
ATOM   945  N NZ   . LYS   A 1 66  ? 15.55854 -7.87749  3.16793  1.000 109.15200 ? 63  LYS   A NZ   1 
ATOM   946  H H    . LYS   A 1 66  ? 20.36187 -5.48881  4.69804  1.000 62.80413  ? 63  LYS   A H    1 
ATOM   947  H HA   . LYS   A 1 66  ? 20.44716 -5.64495  2.07021  1.000 80.83326  ? 63  LYS   A HA   1 
ATOM   948  H HB2  . LYS   A 1 66  ? 18.65459 -4.12002  3.63976  1.000 76.95775  ? 63  LYS   A HB2  1 
ATOM   949  H HB3  . LYS   A 1 66  ? 18.44009 -4.46627  2.10368  1.000 76.95775  ? 63  LYS   A HB3  1 
ATOM   950  H HG2  . LYS   A 1 66  ? 17.94145 -6.63303  2.58315  1.000 63.46271  ? 63  LYS   A HG2  1 
ATOM   951  H HG3  . LYS   A 1 66  ? 18.42450 -6.47002  4.08831  1.000 63.46271  ? 63  LYS   A HG3  1 
ATOM   952  H HD2  . LYS   A 1 66  ? 16.59701 -5.01292  4.48186  1.000 102.58554 ? 63  LYS   A HD2  1 
ATOM   953  H HD3  . LYS   A 1 66  ? 16.09321 -5.28119  2.99875  1.000 102.58554 ? 63  LYS   A HD3  1 
ATOM   954  H HE2  . LYS   A 1 66  ? 16.26754 -7.30235  4.96325  1.000 119.23511 ? 63  LYS   A HE2  1 
ATOM   955  H HE3  . LYS   A 1 66  ? 14.90794 -6.58185  4.56603  1.000 119.23511 ? 63  LYS   A HE3  1 
ATOM   956  H HZ1  . LYS   A 1 66  ? 15.11190 -7.50773  2.49273  1.000 131.00105 ? 63  LYS   A HZ1  1 
ATOM   957  H HZ2  . LYS   A 1 66  ? 16.34133 -8.17589  2.86742  1.000 131.00105 ? 63  LYS   A HZ2  1 
ATOM   958  H HZ3  . LYS   A 1 66  ? 15.08900 -8.56486  3.48282  1.000 131.00105 ? 63  LYS   A HZ3  1 
ATOM   959  N N    . GLU   A 1 67  ? 21.69256 -3.05183  3.30552  1.000 50.46817  ? 64  GLU   A N    1 
ATOM   960  C CA   . GLU   A 1 67  ? 22.31355 -1.76381  3.03488  1.000 48.60582  ? 64  GLU   A CA   1 
ATOM   961  C C    . GLU   A 1 67  ? 23.80433 -1.88798  2.76010  1.000 44.21815  ? 64  GLU   A C    1 
ATOM   962  O O    . GLU   A 1 67  ? 24.53847 -0.90312  2.88365  1.000 49.94753  ? 64  GLU   A O    1 
ATOM   963  C CB   . GLU   A 1 67  ? 22.05975 -0.80469  4.19571  1.000 50.74354  ? 64  GLU   A CB   1 
ATOM   964  C CG   . GLU   A 1 67  ? 20.58298 -0.47799  4.38879  1.000 91.70535  ? 64  GLU   A CG   1 
ATOM   965  C CD   . GLU   A 1 67  ? 20.33586 0.48251   5.53366  1.000 103.09061 ? 64  GLU   A CD   1 
ATOM   966  O OE1  . GLU   A 1 67  ? 20.72134 0.15821   6.67837  1.000 96.42867  ? 64  GLU   A OE1  1 
ATOM   967  O OE2  . GLU   A 1 67  ? 19.76377 1.56632   5.28495  1.000 98.60014  ? 64  GLU   A OE2  1 
ATOM   968  H H    A GLU   A 1 67  ? 21.84181 -3.35064  4.09801  0.590 60.58046  ? 64  GLU   A H    1 
ATOM   969  H H    B GLU   A 1 67  ? 21.84181 -3.35064  4.09801  0.410 60.58046  ? 64  GLU   A H    1 
ATOM   970  H HA   . GLU   A 1 67  ? 21.90259 -1.38298  2.24306  1.000 58.34564  ? 64  GLU   A HA   1 
ATOM   971  H HB2  . GLU   A 1 67  ? 22.38619 -1.20899  5.01478  1.000 60.91090  ? 64  GLU   A HB2  1 
ATOM   972  H HB3  . GLU   A 1 67  ? 22.53015 0.02638   4.02556  1.000 60.91090  ? 64  GLU   A HB3  1 
ATOM   973  H HG2  . GLU   A 1 67  ? 20.24133 -0.07067  3.57746  1.000 110.06507 ? 64  GLU   A HG2  1 
ATOM   974  H HG3  . GLU   A 1 67  ? 20.10044 -1.29817  4.57686  1.000 110.06507 ? 64  GLU   A HG3  1 
ATOM   975  N N    . GLY   A 1 68  ? 24.26353 -3.07424  2.37769  1.000 50.07258  ? 65  GLY   A N    1 
ATOM   976  C CA   . GLY   A 1 68  ? 25.63425 -3.25752  1.97348  1.000 55.10901  ? 65  GLY   A CA   1 
ATOM   977  C C    . GLY   A 1 68  ? 25.93502 -2.54371  0.67351  1.000 63.79177  ? 65  GLY   A C    1 
ATOM   978  O O    . GLY   A 1 68  ? 25.11678 -1.77982  0.15177  1.000 68.79903  ? 65  GLY   A O    1 
ATOM   979  H H    . GLY   A 1 68  ? 23.78922 -3.79093  2.34627  1.000 60.10575  ? 65  GLY   A H    1 
ATOM   980  H HA2  . GLY   A 1 68  ? 26.22367 -2.90879  2.66041  1.000 66.14947  ? 65  GLY   A HA2  1 
ATOM   981  H HA3  . GLY   A 1 68  ? 25.81290 -4.20347  1.85447  1.000 66.14947  ? 65  GLY   A HA3  1 
ATOM   982  N N    . PRO   A 1 69  ? 27.13750 -2.76425  0.12839  1.000 58.22764  ? 66  PRO   A N    1 
ATOM   983  C CA   . PRO   A 1 69  ? 28.19581 -3.57825  0.73127  1.000 61.01779  ? 66  PRO   A CA   1 
ATOM   984  C C    . PRO   A 1 69  ? 29.04778 -2.73899  1.67340  1.000 43.13612  ? 66  PRO   A C    1 
ATOM   985  O O    . PRO   A 1 69  ? 29.00995 -1.50713  1.59529  1.000 43.90980  ? 66  PRO   A O    1 
ATOM   986  C CB   . PRO   A 1 69  ? 28.99892 -4.03697  -0.47918 1.000 53.82327  ? 66  PRO   A CB   1 
ATOM   987  C CG   . PRO   A 1 69  ? 28.92553 -2.84143  -1.40268 1.000 67.60683  ? 66  PRO   A CG   1 
ATOM   988  C CD   . PRO   A 1 69  ? 27.57761 -2.17119  -1.14956 1.000 66.18921  ? 66  PRO   A CD   1 
ATOM   989  H HA   . PRO   A 1 69  ? 27.85028 -4.35714  1.19478  1.000 73.24000  ? 66  PRO   A HA   1 
ATOM   990  H HB2  . PRO   A 1 69  ? 29.91405 -4.23313  -0.22430 1.000 64.60658  ? 66  PRO   A HB2  1 
ATOM   991  H HB3  . PRO   A 1 69  ? 28.59083 -4.82056  -0.87962 1.000 64.60658  ? 66  PRO   A HB3  1 
ATOM   992  H HG2  . PRO   A 1 69  ? 29.65204 -2.23141  -1.20029 1.000 81.14685  ? 66  PRO   A HG2  1 
ATOM   993  H HG3  . PRO   A 1 69  ? 28.98951 -3.13968  -2.32347 1.000 81.14685  ? 66  PRO   A HG3  1 
ATOM   994  H HD2  . PRO   A 1 69  ? 27.68014 -1.21018  -1.06687 1.000 79.44571  ? 66  PRO   A HD2  1 
ATOM   995  H HD3  . PRO   A 1 69  ? 26.95050 -2.37801  -1.86010 1.000 79.44571  ? 66  PRO   A HD3  1 
ATOM   996  N N    . TYR   A 1 70  ? 29.81427 -3.39762  2.53553  1.000 39.33490  ? 67  TYR   A N    1 
ATOM   997  C CA   . TYR   A 1 70  ? 30.64925 -2.72441  3.51945  1.000 29.66124  ? 67  TYR   A CA   1 
ATOM   998  C C    . TYR   A 1 70  ? 32.11527 -2.89164  3.17019  1.000 25.67394  ? 67  TYR   A C    1 
ATOM   999  O O    . TYR   A 1 70  ? 32.51985 -3.93393  2.65005  1.000 29.36656  ? 67  TYR   A O    1 
ATOM   1000 C CB   . TYR   A 1 70  ? 30.37484 -3.26277  4.92645  1.000 28.69854  ? 67  TYR   A CB   1 
ATOM   1001 C CG   . TYR   A 1 70  ? 28.97053 -3.00233  5.36477  1.000 24.13404  ? 67  TYR   A CG   1 
ATOM   1002 C CD1  . TYR   A 1 70  ? 27.95955 -3.89836  5.06997  1.000 31.83341  ? 67  TYR   A CD1  1 
ATOM   1003 C CD2  . TYR   A 1 70  ? 28.64148 -1.84286  6.04898  1.000 26.52446  ? 67  TYR   A CD2  1 
ATOM   1004 C CE1  . TYR   A 1 70  ? 26.66862 -3.66196  5.45611  1.000 27.56509  ? 67  TYR   A CE1  1 
ATOM   1005 C CE2  . TYR   A 1 70  ? 27.35202 -1.59374  6.43414  1.000 35.62270  ? 67  TYR   A CE2  1 
ATOM   1006 C CZ   . TYR   A 1 70  ? 26.36612 -2.50735  6.13604  1.000 36.59438  ? 67  TYR   A CZ   1 
ATOM   1007 O OH   . TYR   A 1 70  ? 25.07418 -2.26035  6.52703  1.000 33.76480  ? 67  TYR   A OH   1 
ATOM   1008 H H    . TYR   A 1 70  ? 29.86763 -4.25530  2.56944  1.000 47.22054  ? 67  TYR   A H    1 
ATOM   1009 H HA   . TYR   A 1 70  ? 30.45251 -1.77459  3.51328  1.000 35.61215  ? 67  TYR   A HA   1 
ATOM   1010 H HB2  . TYR   A 1 70  ? 30.52186 -4.22153  4.93448  1.000 34.45691  ? 67  TYR   A HB2  1 
ATOM   1011 H HB3  . TYR   A 1 70  ? 30.97362 -2.83003  5.55502  1.000 34.45691  ? 67  TYR   A HB3  1 
ATOM   1012 H HD1  . TYR   A 1 70  ? 28.16077 -4.67569  4.60075  1.000 38.21874  ? 67  TYR   A HD1  1 
ATOM   1013 H HD2  . TYR   A 1 70  ? 29.30688 -1.22481  6.24939  1.000 31.84801  ? 67  TYR   A HD2  1 
ATOM   1014 H HE1  . TYR   A 1 70  ? 26.00065 -4.27851  5.25970  1.000 33.09676  ? 67  TYR   A HE1  1 
ATOM   1015 H HE2  . TYR   A 1 70  ? 27.14324 -0.81281  6.89399  1.000 42.76589  ? 67  TYR   A HE2  1 
ATOM   1016 H HH   . TYR   A 1 70  ? 24.56610 -2.86333  6.23741  1.000 40.53641  ? 67  TYR   A HH   1 
ATOM   1017 N N    . ASP   A 1 71  ? 32.89616 -1.86222  3.45096  1.000 26.27072  ? 68  ASP   A N    1 
ATOM   1018 C CA   . ASP   A 1 71  ? 34.32356 -1.93307  3.18905  1.000 22.80897  ? 68  ASP   A CA   1 
ATOM   1019 C C    . ASP   A 1 71  ? 35.04211 -2.81194  4.20537  1.000 26.48651  ? 68  ASP   A C    1 
ATOM   1020 O O    . ASP   A 1 71  ? 36.09695 -3.36923  3.89034  1.000 27.86668  ? 68  ASP   A O    1 
ATOM   1021 C CB   . ASP   A 1 71  ? 34.90152 -0.52217  3.17149  1.000 26.92911  ? 68  ASP   A CB   1 
ATOM   1022 C CG   . ASP   A 1 71  ? 34.25148 0.34221   2.11837  1.000 34.38482  ? 68  ASP   A CG   1 
ATOM   1023 O OD1  . ASP   A 1 71  ? 34.54710 0.13951   0.92768  1.000 38.20124  ? 68  ASP   A OD1  1 
ATOM   1024 O OD2  . ASP   A 1 71  ? 33.41123 1.18184   2.47421  1.000 28.76647  ? 68  ASP   A OD2  1 
ATOM   1025 H H    . ASP   A 1 71  ? 32.62916 -1.11834  3.79000  1.000 31.54351  ? 68  ASP   A H    1 
ATOM   1026 H HA   . ASP   A 1 71  ? 34.47416 -2.32944  2.31663  1.000 27.38941  ? 68  ASP   A HA   1 
ATOM   1027 H HB2  . ASP   A 1 71  ? 34.75641 -0.10721  4.03616  1.000 32.33359  ? 68  ASP   A HB2  1 
ATOM   1028 H HB3  . ASP   A 1 71  ? 35.85152 -0.56895  2.98121  1.000 32.33359  ? 68  ASP   A HB3  1 
ATOM   1029 N N    . VAL   A 1 72  ? 34.49497 -2.95759  5.41070  1.000 23.92259  ? 69  VAL   A N    1 
ATOM   1030 C CA   . VAL   A 1 72  ? 35.01564 -3.89825  6.39903  1.000 24.03412  ? 69  VAL   A CA   1 
ATOM   1031 C C    . VAL   A 1 72  ? 33.84537 -4.52397  7.15558  1.000 23.29674  ? 69  VAL   A C    1 
ATOM   1032 O O    . VAL   A 1 72  ? 32.82843 -3.86694  7.42290  1.000 24.70705  ? 69  VAL   A O    1 
ATOM   1033 C CB   . VAL   A 1 72  ? 36.01245 -3.20990  7.36240  1.000 21.45978  ? 69  VAL   A CB   1 
ATOM   1034 C CG1  . VAL   A 1 72  ? 35.32643 -2.12020  8.17635  1.000 29.06063  ? 69  VAL   A CG1  1 
ATOM   1035 C CG2  . VAL   A 1 72  ? 36.69761 -4.24024  8.27035  1.000 23.70644  ? 69  VAL   A CG2  1 
ATOM   1036 H H    . VAL   A 1 72  ? 33.80987 -2.51485  5.68314  1.000 28.72577  ? 69  VAL   A H    1 
ATOM   1037 H HA   . VAL   A 1 72  ? 35.48336 -4.61607  5.94420  1.000 28.85960  ? 69  VAL   A HA   1 
ATOM   1038 H HB   . VAL   A 1 72  ? 36.70374 -2.78198  6.83335  1.000 25.77039  ? 69  VAL   A HB   1 
ATOM   1039 H HG11 . VAL   A 1 72  ? 36.00238 -1.58662  8.62276  1.000 34.89141  ? 69  VAL   A HG11 1 
ATOM   1040 H HG12 . VAL   A 1 72  ? 34.80477 -1.56125  7.57941  1.000 34.89141  ? 69  VAL   A HG12 1 
ATOM   1041 H HG13 . VAL   A 1 72  ? 34.74548 -2.53502  8.83311  1.000 34.89141  ? 69  VAL   A HG13 1 
ATOM   1042 H HG21 . VAL   A 1 72  ? 37.38026 -3.79397  8.79544  1.000 28.46638  ? 69  VAL   A HG21 1 
ATOM   1043 H HG22 . VAL   A 1 72  ? 36.03382 -4.63466  8.85748  1.000 28.46638  ? 69  VAL   A HG22 1 
ATOM   1044 H HG23 . VAL   A 1 72  ? 37.10169 -4.92813  7.71860  1.000 28.46638  ? 69  VAL   A HG23 1 
ATOM   1045 N N    . VAL   A 1 73  ? 33.97110 -5.81648  7.45491  1.000 21.16229  ? 70  VAL   A N    1 
ATOM   1046 C CA   . VAL   A 1 73  ? 33.09047 -6.51353  8.38655  1.000 20.46822  ? 70  VAL   A CA   1 
ATOM   1047 C C    . VAL   A 1 73  ? 33.91996 -6.86843  9.60859  1.000 26.94046  ? 70  VAL   A C    1 
ATOM   1048 O O    . VAL   A 1 73  ? 34.98977 -7.47951  9.48159  1.000 23.82525  ? 70  VAL   A O    1 
ATOM   1049 C CB   . VAL   A 1 73  ? 32.46285 -7.76895  7.76299  1.000 26.05609  ? 70  VAL   A CB   1 
ATOM   1050 C CG1  . VAL   A 1 73  ? 31.61166 -8.49974  8.79004  1.000 25.11968  ? 70  VAL   A CG1  1 
ATOM   1051 C CG2  . VAL   A 1 73  ? 31.62591 -7.37388  6.55269  1.000 31.91476  ? 70  VAL   A CG2  1 
ATOM   1052 H H    . VAL   A 1 73  ? 34.57857 -6.32440  7.11936  1.000 25.41340  ? 70  VAL   A H    1 
ATOM   1053 H HA   . VAL   A 1 73  ? 32.36487 -5.92587  8.64933  1.000 24.58052  ? 70  VAL   A HA   1 
ATOM   1054 H HB   . VAL   A 1 73  ? 33.16345 -8.37344  7.47205  1.000 31.28596  ? 70  VAL   A HB   1 
ATOM   1055 H HG11 . VAL   A 1 73  ? 31.09778 -9.18922  8.34122  1.000 30.16228  ? 70  VAL   A HG11 1 
ATOM   1056 H HG12 . VAL   A 1 73  ? 32.19346 -8.90063  9.45464  1.000 30.16228  ? 70  VAL   A HG12 1 
ATOM   1057 H HG13 . VAL   A 1 73  ? 31.01356 -7.86457  9.21398  1.000 30.16228  ? 70  VAL   A HG13 1 
ATOM   1058 H HG21 . VAL   A 1 73  ? 31.28180 -8.17679  6.13101  1.000 38.31637  ? 70  VAL   A HG21 1 
ATOM   1059 H HG22 . VAL   A 1 73  ? 30.89071 -6.81346  6.84648  1.000 38.31637  ? 70  VAL   A HG22 1 
ATOM   1060 H HG23 . VAL   A 1 73  ? 32.18481 -6.88572  5.92800  1.000 38.31637  ? 70  VAL   A HG23 1 
ATOM   1061 N N    . VAL   A 1 74  ? 33.43565 -6.47108  10.78507 1.000 22.90144  ? 71  VAL   A N    1 
ATOM   1062 C CA   . VAL   A 1 74  ? 34.18469 -6.56323  12.03114 1.000 22.63781  ? 71  VAL   A CA   1 
ATOM   1063 C C    . VAL   A 1 74  ? 33.49301 -7.56164  12.94510 1.000 22.55357  ? 71  VAL   A C    1 
ATOM   1064 O O    . VAL   A 1 74  ? 32.29807 -7.42741  13.24253 1.000 21.93576  ? 71  VAL   A O    1 
ATOM   1065 C CB   . VAL   A 1 74  ? 34.30823 -5.19143  12.71620 1.000 21.55587  ? 71  VAL   A CB   1 
ATOM   1066 C CG1  . VAL   A 1 74  ? 35.06812 -5.33196  14.00724 1.000 23.70907  ? 71  VAL   A CG1  1 
ATOM   1067 C CG2  . VAL   A 1 74  ? 35.00174 -4.20686  11.80570 1.000 23.31571  ? 71  VAL   A CG2  1 
ATOM   1068 H H    . VAL   A 1 74  ? 32.65062 -6.13475  10.88613 1.000 27.50038  ? 71  VAL   A H    1 
ATOM   1069 H HA   . VAL   A 1 74  ? 35.07568 -6.89495  11.83877 1.000 27.18403  ? 71  VAL   A HA   1 
ATOM   1070 H HB   . VAL   A 1 74  ? 33.42098 -4.85090  12.91043 1.000 25.88570  ? 71  VAL   A HB   1 
ATOM   1071 H HG11 . VAL   A 1 74  ? 35.35337 -4.45331  14.30304 1.000 28.46954  ? 71  VAL   A HG11 1 
ATOM   1072 H HG12 . VAL   A 1 74  ? 34.48788 -5.73294  14.67316 1.000 28.46954  ? 71  VAL   A HG12 1 
ATOM   1073 H HG13 . VAL   A 1 74  ? 35.84156 -5.89812  13.85843 1.000 28.46954  ? 71  VAL   A HG13 1 
ATOM   1074 H HG21 . VAL   A 1 74  ? 35.03550 -3.34179  12.24321 1.000 27.99750  ? 71  VAL   A HG21 1 
ATOM   1075 H HG22 . VAL   A 1 74  ? 35.90136 -4.52215  11.62634 1.000 27.99750  ? 71  VAL   A HG22 1 
ATOM   1076 H HG23 . VAL   A 1 74  ? 34.50356 -4.13880  10.97619 1.000 27.99750  ? 71  VAL   A HG23 1 
ATOM   1077 N N    . LEU   A 1 75  ? 34.25643 -8.54776  13.40522 1.000 18.82910  ? 72  LEU   A N    1 
ATOM   1078 C CA   . LEU   A 1 75  ? 33.78049 -9.59307  14.30223 1.000 18.59615  ? 72  LEU   A CA   1 
ATOM   1079 C C    . LEU   A 1 75  ? 34.44671 -9.44479  15.66378 1.000 22.21895  ? 72  LEU   A C    1 
ATOM   1080 O O    . LEU   A 1 75  ? 35.62833 -9.79781  15.82297 1.000 22.31652  ? 72  LEU   A O    1 
ATOM   1081 C CB   . LEU   A 1 75  ? 34.07792 -10.97123 13.71265 1.000 21.13178  ? 72  LEU   A CB   1 
ATOM   1082 C CG   . LEU   A 1 75  ? 33.53082 -11.27931 12.31567 1.000 23.59958  ? 72  LEU   A CG   1 
ATOM   1083 C CD1  . LEU   A 1 75  ? 33.97987 -12.68596 11.93900 1.000 32.93139  ? 72  LEU   A CD1  1 
ATOM   1084 C CD2  . LEU   A 1 75  ? 32.03776 -11.18557 12.28587 1.000 27.10035  ? 72  LEU   A CD2  1 
ATOM   1085 H H    . LEU   A 1 75  ? 35.08775 -8.63602  13.20343 1.000 22.61358  ? 72  LEU   A H    1 
ATOM   1086 H HA   . LEU   A 1 75  ? 32.82208 -9.50097  14.41997 1.000 22.33403  ? 72  LEU   A HA   1 
ATOM   1087 H HB2  . LEU   A 1 75  ? 35.04159 -11.07076 13.66433 1.000 25.37679  ? 72  LEU   A HB2  1 
ATOM   1088 H HB3  . LEU   A 1 75  ? 33.70535 -11.63638 14.31238 1.000 25.37679  ? 72  LEU   A HB3  1 
ATOM   1089 H HG   . LEU   A 1 75  ? 33.86670 -10.63441 11.67364 1.000 28.33816  ? 72  LEU   A HG   1 
ATOM   1090 H HD11 . LEU   A 1 75  ? 33.61879 -12.90986 11.06700 1.000 39.53633  ? 72  LEU   A HD11 1 
ATOM   1091 H HD12 . LEU   A 1 75  ? 34.94916 -12.71145 11.91213 1.000 39.53633  ? 72  LEU   A HD12 1 
ATOM   1092 H HD13 . LEU   A 1 75  ? 33.65084 -13.31111 12.60371 1.000 39.53633  ? 72  LEU   A HD13 1 
ATOM   1093 H HD21 . LEU   A 1 75  ? 31.71954 -11.48805 11.42092 1.000 32.53907  ? 72  LEU   A HD21 1 
ATOM   1094 H HD22 . LEU   A 1 75  ? 31.67205 -11.74662 12.98757 1.000 32.53907  ? 72  LEU   A HD22 1 
ATOM   1095 H HD23 . LEU   A 1 75  ? 31.77633 -10.26269 12.43027 1.000 32.53907  ? 72  LEU   A HD23 1 
ATOM   1096 N N    . PRO   A 1 76  ? 33.75305 -8.92071  16.67018 1.000 29.37358  ? 73  PRO   A N    1 
ATOM   1097 C CA   . PRO   A 1 76  ? 34.33357 -8.87661  18.01316 1.000 23.91201  ? 73  PRO   A CA   1 
ATOM   1098 C C    . PRO   A 1 76  ? 34.50068 -10.28080 18.56475 1.000 22.13903  ? 73  PRO   A C    1 
ATOM   1099 O O    . PRO   A 1 76  ? 33.96938 -11.26426 18.03852 1.000 21.76261  ? 73  PRO   A O    1 
ATOM   1100 C CB   . PRO   A 1 76  ? 33.32437 -8.07563  18.84120 1.000 23.62323  ? 73  PRO   A CB   1 
ATOM   1101 C CG   . PRO   A 1 76  ? 32.33564 -7.50331  17.84042 1.000 26.49089  ? 73  PRO   A CG   1 
ATOM   1102 C CD   . PRO   A 1 76  ? 32.37539 -8.40623  16.64934 1.000 20.24632  ? 73  PRO   A CD   1 
ATOM   1103 H HA   . PRO   A 1 76  ? 35.18163 -8.40583  18.00604 1.000 28.71307  ? 73  PRO   A HA   1 
ATOM   1104 H HB2  . PRO   A 1 76  ? 32.87715 -8.66319  19.47022 1.000 28.36653  ? 73  PRO   A HB2  1 
ATOM   1105 H HB3  . PRO   A 1 76  ? 33.78211 -7.36576  19.31812 1.000 28.36653  ? 73  PRO   A HB3  1 
ATOM   1106 H HG2  . PRO   A 1 76  ? 31.44773 -7.49094  18.23076 1.000 31.80772  ? 73  PRO   A HG2  1 
ATOM   1107 H HG3  . PRO   A 1 76  ? 32.60339 -6.60345  17.59655 1.000 31.80772  ? 73  PRO   A HG3  1 
ATOM   1108 H HD2  . PRO   A 1 76  ? 31.73448 -9.12857  16.74075 1.000 24.31424  ? 73  PRO   A HD2  1 
ATOM   1109 H HD3  . PRO   A 1 76  ? 32.20292 -7.91096  15.83334 1.000 24.31424  ? 73  PRO   A HD3  1 
ATOM   1110 N N    . GLY   A 1 77  ? 35.23137 -10.36184 19.66742 1.000 21.81526  ? 74  GLY   A N    1 
ATOM   1111 C CA   . GLY   A 1 77  ? 35.45193 -11.59454 20.35566 1.000 18.65863  ? 74  GLY   A CA   1 
ATOM   1112 C C    . GLY   A 1 77  ? 34.49560 -11.79524 21.51230 1.000 22.71706  ? 74  GLY   A C    1 
ATOM   1113 O O    . GLY   A 1 77  ? 33.35350 -11.31708 21.49767 1.000 22.07262  ? 74  GLY   A O    1 
ATOM   1114 H H    A GLY   A 1 77  ? 35.61599 -9.68717  20.03685 0.719 26.19697  ? 74  GLY   A H    1 
ATOM   1115 H H    B GLY   A 1 77  ? 35.61599 -9.68717  20.03685 0.281 26.19697  ? 74  GLY   A H    1 
ATOM   1116 H HA2  . GLY   A 1 77  ? 35.33914 -12.33194 19.73564 1.000 22.40901  ? 74  GLY   A HA2  1 
ATOM   1117 H HA3  . GLY   A 1 77  ? 36.35750 -11.60966 20.70296 1.000 22.40901  ? 74  GLY   A HA3  1 
ATOM   1118 N N    . GLY   A 1 78  ? 34.98163 -12.45976 22.55190 1.000 20.90446  ? 75  GLY   A N    1 
ATOM   1119 C CA   . GLY   A 1 78  ? 34.11611 -13.01089 23.57808 1.000 20.76801  ? 75  GLY   A CA   1 
ATOM   1120 C C    . GLY   A 1 78  ? 33.76848 -14.44071 23.20826 1.000 20.96194  ? 75  GLY   A C    1 
ATOM   1121 O O    . GLY   A 1 78  ? 33.26162 -14.68779 22.10895 1.000 23.56945  ? 75  GLY   A O    1 
ATOM   1122 H H    . GLY   A 1 78  ? 35.81852 -12.60568 22.68579 1.000 25.10401  ? 75  GLY   A H    1 
ATOM   1123 H HA2  . GLY   A 1 78  ? 34.56726 -13.00201 24.43674 1.000 24.94027  ? 75  GLY   A HA2  1 
ATOM   1124 H HA3  . GLY   A 1 78  ? 33.30104 -12.48917 23.64419 1.000 24.94027  ? 75  GLY   A HA3  1 
ATOM   1125 N N    . ASN   A 1 79  ? 34.06709 -15.39339 24.09860 1.000 23.76351  ? 76  ASN   A N    1 
ATOM   1126 C CA   . ASN   A 1 79  ? 33.89877 -16.80378 23.75739 1.000 25.69178  ? 76  ASN   A CA   1 
ATOM   1127 C C    . ASN   A 1 79  ? 32.47796 -17.09542 23.30343 1.000 24.30057  ? 76  ASN   A C    1 
ATOM   1128 O O    . ASN   A 1 79  ? 32.26550 -17.70242 22.24562 1.000 23.33873  ? 76  ASN   A O    1 
ATOM   1129 C CB   . ASN   A 1 79  ? 34.27244 -17.68191 24.94767 1.000 29.86802  ? 76  ASN   A CB   1 
ATOM   1130 C CG   . ASN   A 1 79  ? 35.76508 -17.83577 25.10214 1.000 38.63313  ? 76  ASN   A CG   1 
ATOM   1131 O OD1  . ASN   A 1 79  ? 36.50794 -17.82432 24.12052 1.000 60.42438  ? 76  ASN   A OD1  1 
ATOM   1132 N ND2  . ASN   A 1 79  ? 36.21827 -17.98164 26.33802 1.000 65.05169  ? 76  ASN   A ND2  1 
ATOM   1133 H H    . ASN   A 1 79  ? 34.36366 -15.24961 24.89294 1.000 28.53487  ? 76  ASN   A H    1 
ATOM   1134 H HA   . ASN   A 1 79  ? 34.49844 -17.01731 23.02547 1.000 30.84879  ? 76  ASN   A HA   1 
ATOM   1135 H HB2  . ASN   A 1 79  ? 33.92508 -17.28072 25.75964 1.000 35.86028  ? 76  ASN   A HB2  1 
ATOM   1136 H HB3  . ASN   A 1 79  ? 33.88962 -18.56450 24.82366 1.000 35.86028  ? 76  ASN   A HB3  1 
ATOM   1137 H HD21 . ASN   A 1 79  ? 37.06174 -18.07304 26.47874 1.000 78.08068  ? 76  ASN   A HD21 1 
ATOM   1138 H HD22 . ASN   A 1 79  ? 35.66907 -17.98496 26.99981 1.000 78.08068  ? 76  ASN   A HD22 1 
ATOM   1139 N N    . LEU   A 1 80  ? 31.48222 -16.64672 24.07327 1.000 20.32201  ? 77  LEU   A N    1 
ATOM   1140 C CA   . LEU   A 1 80  ? 30.10653 -16.98358 23.72399 1.000 21.54261  ? 77  LEU   A CA   1 
ATOM   1141 C C    . LEU   A 1 80  ? 29.62432 -16.16562 22.53860 1.000 29.69483  ? 77  LEU   A C    1 
ATOM   1142 O O    . LEU   A 1 80  ? 28.86785 -16.67330 21.70719 1.000 24.55168  ? 77  LEU   A O    1 
ATOM   1143 C CB   . LEU   A 1 80  ? 29.19286 -16.79362 24.92729 1.000 29.40528  ? 77  LEU   A CB   1 
ATOM   1144 C CG   . LEU   A 1 80  ? 29.58334 -17.64644 26.14584 1.000 31.90459  ? 77  LEU   A CG   1 
ATOM   1145 C CD1  . LEU   A 1 80  ? 28.60168 -17.40469 27.28739 1.000 72.33621  ? 77  LEU   A CD1  1 
ATOM   1146 C CD2  . LEU   A 1 80  ? 29.65195 -19.12575 25.82024 1.000 53.77219  ? 77  LEU   A CD2  1 
ATOM   1147 H H    . LEU   A 1 80  ? 31.57631 -16.16271 24.77789 1.000 24.40506  ? 77  LEU   A H    1 
ATOM   1148 H HA   . LEU   A 1 80  ? 30.05577 -17.92094 23.47972 1.000 25.86979  ? 77  LEU   A HA   1 
ATOM   1149 H HB2  . LEU   A 1 80  ? 29.22241 -15.86202 25.19589 1.000 35.30499  ? 77  LEU   A HB2  1 
ATOM   1150 H HB3  . LEU   A 1 80  ? 28.28906 -17.03697 24.67267 1.000 35.30499  ? 77  LEU   A HB3  1 
ATOM   1151 H HG   . LEU   A 1 80  ? 30.47349 -17.37906 26.42340 1.000 38.30416  ? 77  LEU   A HG   1 
ATOM   1152 H HD11 . LEU   A 1 80  ? 28.85297 -17.95898 28.04272 1.000 86.82211  ? 77  LEU   A HD11 1 
ATOM   1153 H HD12 . LEU   A 1 80  ? 28.63414 -16.46842 27.53887 1.000 86.82211  ? 77  LEU   A HD12 1 
ATOM   1154 H HD13 . LEU   A 1 80  ? 27.70801 -17.63648 26.98983 1.000 86.82211  ? 77  LEU   A HD13 1 
ATOM   1155 H HD21 . LEU   A 1 80  ? 30.42688 -19.29030 25.26050 1.000 64.54529  ? 77  LEU   A HD21 1 
ATOM   1156 H HD22 . LEU   A 1 80  ? 29.72825 -19.62780 26.64669 1.000 64.54529  ? 77  LEU   A HD22 1 
ATOM   1157 H HD23 . LEU   A 1 80  ? 28.84359 -19.38345 25.35009 1.000 64.54529  ? 77  LEU   A HD23 1 
ATOM   1158 N N    . GLY   A 1 81  ? 30.07410 -14.91715 22.42687 1.000 21.65015  ? 78  GLY   A N    1 
ATOM   1159 C CA   . GLY   A 1 81  ? 29.75206 -14.13748 21.24872 1.000 29.16078  ? 78  GLY   A CA   1 
ATOM   1160 C C    . GLY   A 1 81  ? 30.26092 -14.80151 19.98859 1.000 24.36820  ? 78  GLY   A C    1 
ATOM   1161 O O    . GLY   A 1 81  ? 29.54122 -14.90887 18.98822 1.000 23.35332  ? 78  GLY   A O    1 
ATOM   1162 H H    . GLY   A 1 81  ? 30.55775 -14.51016 23.01001 1.000 25.99883  ? 78  GLY   A H    1 
ATOM   1163 H HA2  . GLY   A 1 81  ? 28.78977 -14.03738 21.17887 1.000 35.01160  ? 78  GLY   A HA2  1 
ATOM   1164 H HA3  . GLY   A 1 81  ? 30.15658 -13.25878 21.32052 1.000 35.01160  ? 78  GLY   A HA3  1 
ATOM   1165 N N    . ALA   A 1 82  ? 31.50747 -15.27574 20.02664 1.000 20.37223  ? 79  ALA   A N    1 
ATOM   1166 C CA   . ALA   A 1 82  ? 32.09630 -15.90746 18.85209 1.000 20.02898  ? 79  ALA   A CA   1 
ATOM   1167 C C    . ALA   A 1 82  ? 31.37975 -17.20350 18.49668 1.000 23.39001  ? 79  ALA   A C    1 
ATOM   1168 O O    . ALA   A 1 82  ? 31.26239 -17.54094 17.31303 1.000 24.79841  ? 79  ALA   A O    1 
ATOM   1169 C CB   . ALA   A 1 82  ? 33.58081 -16.19629 19.08261 1.000 22.59081  ? 79  ALA   A CB   1 
ATOM   1170 H H    . ALA   A 1 82  ? 32.02536 -15.24370 20.71247 1.000 24.46533  ? 79  ALA   A H    1 
ATOM   1171 H HA   . ALA   A 1 82  ? 32.01865 -15.29063 18.10752 1.000 24.05343  ? 79  ALA   A HA   1 
ATOM   1172 H HB1  . ALA   A 1 82  ? 33.95393 -16.59220 18.27952 1.000 27.12763  ? 79  ALA   A HB1  1 
ATOM   1173 H HB2  . ALA   A 1 82  ? 34.03690 -15.36418 19.28382 1.000 27.12763  ? 79  ALA   A HB2  1 
ATOM   1174 H HB3  . ALA   A 1 82  ? 33.67096 -16.81135 19.82723 1.000 27.12763  ? 79  ALA   A HB3  1 
ATOM   1175 N N    A GLN   A 1 83  ? 30.90205 -17.93898 19.49984 0.506 20.22440  ? 80  GLN   A N    1 
ATOM   1176 N N    B GLN   A 1 83  ? 30.90926 -17.94314 19.49895 0.494 20.26798  ? 80  GLN   A N    1 
ATOM   1177 C CA   A GLN   A 1 83  ? 30.14795 -19.15778 19.22486 0.506 25.18058  ? 80  GLN   A CA   1 
ATOM   1178 C CA   B GLN   A 1 83  ? 30.14722 -19.15369 19.21812 0.494 25.18748  ? 80  GLN   A CA   1 
ATOM   1179 C C    A GLN   A 1 83  ? 28.83200 -18.83138 18.52801 0.506 25.26689  ? 80  GLN   A C    1 
ATOM   1180 C C    B GLN   A 1 83  ? 28.84779 -18.81063 18.50279 0.494 25.31904  ? 80  GLN   A C    1 
ATOM   1181 O O    A GLN   A 1 83  ? 28.42946 -19.52353 17.58518 0.506 28.11979  ? 80  GLN   A O    1 
ATOM   1182 O O    B GLN   A 1 83  ? 28.47050 -19.46889 17.52598 0.494 27.90387  ? 80  GLN   A O    1 
ATOM   1183 C CB   A GLN   A 1 83  ? 29.90980 -19.92722 20.52483 0.506 28.68065  ? 80  GLN   A CB   1 
ATOM   1184 C CB   B GLN   A 1 83  ? 29.87232 -19.91090 20.51536 0.494 28.70456  ? 80  GLN   A CB   1 
ATOM   1185 C CG   A GLN   A 1 83  ? 31.18385 -20.51048 21.14968 0.506 35.40474  ? 80  GLN   A CG   1 
ATOM   1186 C CG   B GLN   A 1 83  ? 29.19485 -21.26325 20.32414 0.494 31.27001  ? 80  GLN   A CG   1 
ATOM   1187 C CD   A GLN   A 1 83  ? 30.96560 -21.08164 22.54788 0.506 55.16882  ? 80  GLN   A CD   1 
ATOM   1188 C CD   B GLN   A 1 83  ? 28.81026 -21.91258 21.64112 0.494 55.90959  ? 80  GLN   A CD   1 
ATOM   1189 O OE1  A GLN   A 1 83  ? 29.83544 -21.35588 22.94988 0.506 78.53066  ? 80  GLN   A OE1  1 
ATOM   1190 O OE1  B GLN   A 1 83  ? 29.24781 -21.48407 22.70948 0.494 77.37320  ? 80  GLN   A OE1  1 
ATOM   1191 N NE2  A GLN   A 1 83  ? 32.05165 -21.25253 23.29650 0.506 30.88442  ? 80  GLN   A NE2  1 
ATOM   1192 N NE2  B GLN   A 1 83  ? 27.98238 -22.94960 21.57047 0.494 60.32863  ? 80  GLN   A NE2  1 
ATOM   1193 H H    A GLN   A 1 83  ? 30.99923 -17.75709 20.33475 0.506 24.28794  ? 80  GLN   A H    1 
ATOM   1194 H H    B GLN   A 1 83  ? 31.01565 -17.76888 20.33436 0.494 24.34023  ? 80  GLN   A H    1 
ATOM   1195 H HA   A GLN   A 1 83  ? 30.66322 -19.73157 18.63651 0.506 30.23536  ? 80  GLN   A HA   1 
ATOM   1196 H HA   B GLN   A 1 83  ? 30.66678 -19.73704 18.64310 0.494 30.24363  ? 80  GLN   A HA   1 
ATOM   1197 H HB2  A GLN   A 1 83  ? 29.51227 -19.32544 21.17347 0.506 34.43543  ? 80  GLN   A HB2  1 
ATOM   1198 H HB2  B GLN   A 1 83  ? 30.71637 -20.06691 20.96718 0.494 34.46413  ? 80  GLN   A HB2  1 
ATOM   1199 H HB3  A GLN   A 1 83  ? 29.30643 -20.66466 20.34309 0.506 34.43543  ? 80  GLN   A HB3  1 
ATOM   1200 H HB3  B GLN   A 1 83  ? 29.29274 -19.36871 21.07305 0.494 34.46413  ? 80  GLN   A HB3  1 
ATOM   1201 H HG2  A GLN   A 1 83  ? 31.51130 -21.22690 20.58363 0.506 42.50435  ? 80  GLN   A HG2  1 
ATOM   1202 H HG2  B GLN   A 1 83  ? 28.38692 -21.14190 19.80125 0.494 37.54267  ? 80  GLN   A HG2  1 
ATOM   1203 H HG3  A GLN   A 1 83  ? 31.85041 -19.80889 21.21581 0.506 42.50435  ? 80  GLN   A HG3  1 
ATOM   1204 H HG3  B GLN   A 1 83  ? 29.80336 -21.85991 19.86088 0.494 37.54267  ? 80  GLN   A HG3  1 
ATOM   1205 H HE21 A GLN   A 1 83  ? 32.82571 -21.04397 22.98515 0.506 37.07996  ? 80  GLN   A HE21 1 
ATOM   1206 H HE21 B GLN   A 1 83  ? 27.69433 -23.21856 20.80609 0.494 72.41301  ? 80  GLN   A HE21 1 
ATOM   1207 H HE22 A GLN   A 1 83  ? 31.97980 -21.57158 24.09189 0.506 37.07996  ? 80  GLN   A HE22 1 
ATOM   1208 H HE22 B GLN   A 1 83  ? 27.73464 -23.35177 22.28913 0.494 72.41301  ? 80  GLN   A HE22 1 
ATOM   1209 N N    . ASN   A 1 84  ? 28.15976 -17.76330 18.96016 1.000 25.71436  ? 81  ASN   A N    1 
ATOM   1210 C CA   . ASN   A 1 84  ? 26.93676 -17.33950 18.29154 1.000 23.07823  ? 81  ASN   A CA   1 
ATOM   1211 C C    . ASN   A 1 84  ? 27.21104 -16.92287 16.85554 1.000 19.87669  ? 81  ASN   A C    1 
ATOM   1212 O O    . ASN   A 1 84  ? 26.42930 -17.24296 15.95158 1.000 28.77849  ? 81  ASN   A O    1 
ATOM   1213 C CB   . ASN   A 1 84  ? 26.29025 -16.20462 19.08776 1.000 26.05096  ? 81  ASN   A CB   1 
ATOM   1214 C CG   . ASN   A 1 84  ? 25.64688 -16.69720 20.36380 1.000 34.94836  ? 81  ASN   A CG   1 
ATOM   1215 O OD1  . ASN   A 1 84  ? 25.09031 -17.79199 20.39809 1.000 37.61155  ? 81  ASN   A OD1  1 
ATOM   1216 N ND2  . ASN   A 1 84  ? 25.73013 -15.90165 21.42752 1.000 32.40404  ? 81  ASN   A ND2  1 
ATOM   1217 H H    A ASN   A 1 84  ? 28.38930 -17.27473 19.62964 0.506 30.87588  ? 81  ASN   A H    1 
ATOM   1218 H H    B ASN   A 1 84  ? 28.37785 -17.29040 19.64455 0.494 30.87588  ? 81  ASN   A H    1 
ATOM   1219 H HA   . ASN   A 1 84  ? 26.30965 -18.07893 18.26175 1.000 27.71253  ? 81  ASN   A HA   1 
ATOM   1220 H HB2  . ASN   A 1 84  ? 26.96981 -15.55380 19.32343 1.000 31.27981  ? 81  ASN   A HB2  1 
ATOM   1221 H HB3  . ASN   A 1 84  ? 25.60386 -15.78589 18.54513 1.000 31.27981  ? 81  ASN   A HB3  1 
ATOM   1222 H HD21 . ASN   A 1 84  ? 25.37770 -16.14330 22.17384 1.000 38.90350  ? 81  ASN   A HD21 1 
ATOM   1223 H HD22 . ASN   A 1 84  ? 26.13636 -15.14594 21.36854 1.000 38.90350  ? 81  ASN   A HD22 1 
ATOM   1224 N N    . LEU   A 1 85  ? 28.31936 -16.21408 16.62093 1.000 25.92014  ? 82  LEU   A N    1 
ATOM   1225 C CA   . LEU   A 1 85  ? 28.68420 -15.84144 15.25827 1.000 22.85003  ? 82  LEU   A CA   1 
ATOM   1226 C C    . LEU   A 1 85  ? 28.96283 -17.07394 14.40845 1.000 29.89796  ? 82  LEU   A C    1 
ATOM   1227 O O    . LEU   A 1 85  ? 28.64577 -17.09628 13.21560 1.000 25.54957  ? 82  LEU   A O    1 
ATOM   1228 C CB   . LEU   A 1 85  ? 29.91129 -14.93340 15.26692 1.000 22.35273  ? 82  LEU   A CB   1 
ATOM   1229 C CG   . LEU   A 1 85  ? 29.74865 -13.53674 15.88226 1.000 24.43814  ? 82  LEU   A CG   1 
ATOM   1230 C CD1  . LEU   A 1 85  ? 31.10130 -12.83177 15.89019 1.000 28.86124  ? 82  LEU   A CD1  1 
ATOM   1231 C CD2  . LEU   A 1 85  ? 28.73174 -12.72428 15.14160 1.000 30.98719  ? 82  LEU   A CD2  1 
ATOM   1232 H H    . LEU   A 1 85  ? 28.86713 -15.94187 17.22545 1.000 31.12282  ? 82  LEU   A H    1 
ATOM   1233 H HA   . LEU   A 1 85  ? 27.94400 -15.35230 14.86617 1.000 27.43869  ? 82  LEU   A HA   1 
ATOM   1234 H HB2  . LEU   A 1 85  ? 30.60991 -15.38240 15.76815 1.000 26.84193  ? 82  LEU   A HB2  1 
ATOM   1235 H HB3  . LEU   A 1 85  ? 30.19272 -14.80509 14.34756 1.000 26.84193  ? 82  LEU   A HB3  1 
ATOM   1236 H HG   . LEU   A 1 85  ? 29.42789 -13.62380 16.79354 1.000 29.34442  ? 82  LEU   A HG   1 
ATOM   1237 H HD11 . LEU   A 1 85  ? 30.96556 -11.89014 16.07942 1.000 34.65214  ? 82  LEU   A HD11 1 
ATOM   1238 H HD12 . LEU   A 1 85  ? 31.66073 -13.22959 16.57552 1.000 34.65214  ? 82  LEU   A HD12 1 
ATOM   1239 H HD13 . LEU   A 1 85  ? 31.51774 -12.93773 15.02057 1.000 34.65214  ? 82  LEU   A HD13 1 
ATOM   1240 H HD21 . LEU   A 1 85  ? 28.71692 -11.82640 15.50832 1.000 37.20328  ? 82  LEU   A HD21 1 
ATOM   1241 H HD22 . LEU   A 1 85  ? 28.97436 -12.69423 14.20291 1.000 37.20328  ? 82  LEU   A HD22 1 
ATOM   1242 H HD23 . LEU   A 1 85  ? 27.86062 -13.13823 15.24500 1.000 37.20328  ? 82  LEU   A HD23 1 
ATOM   1243 N N    . SER   A 1 86  ? 29.57544 -18.10021 15.00897 1.000 27.36507  ? 83  SER   A N    1 
ATOM   1244 C CA   . SER   A 1 86  ? 29.95286 -19.30069 14.27554 1.000 28.18528  ? 83  SER   A CA   1 
ATOM   1245 C C    . SER   A 1 86  ? 28.73737 -20.12424 13.87498 1.000 28.81708  ? 83  SER   A C    1 
ATOM   1246 O O    . SER   A 1 86  ? 28.78546 -20.85278 12.88018 1.000 30.65557  ? 83  SER   A O    1 
ATOM   1247 C CB   . SER   A 1 86  ? 30.88500 -20.16663 15.12704 1.000 21.98818  ? 83  SER   A CB   1 
ATOM   1248 O OG   . SER   A 1 86  ? 32.11618 -19.52570 15.40206 1.000 28.75317  ? 83  SER   A OG   1 
ATOM   1249 H H    . SER   A 1 86  ? 29.78275 -18.12248 15.84331 1.000 32.85674  ? 83  SER   A H    1 
ATOM   1250 H HA   . SER   A 1 86  ? 30.42310 -19.02849 13.47199 1.000 33.84100  ? 83  SER   A HA   1 
ATOM   1251 H HB2  . SER   A 1 86  ? 30.44323 -20.36194 15.96822 1.000 26.40447  ? 83  SER   A HB2  1 
ATOM   1252 H HB3  . SER   A 1 86  ? 31.06539 -20.99052 14.64791 1.000 26.40447  ? 83  SER   A HB3  1 
ATOM   1253 H HG   . SER   A 1 86  ? 31.98132 -18.81700 15.83236 1.000 34.52246  ? 83  SER   A HG   1 
ATOM   1254 N N    . GLU   A 1 87  ? 27.65619 -20.04140 14.63583 1.000 27.52271  ? 84  GLU   A N    1 
ATOM   1255 C CA   . GLU   A 1 87  ? 26.48487 -20.85302 14.37749 1.000 30.83960  ? 84  GLU   A CA   1 
ATOM   1256 C C    . GLU   A 1 87  ? 25.47825 -20.17562 13.45882 1.000 33.43340  ? 84  GLU   A C    1 
ATOM   1257 O O    . GLU   A 1 87  ? 24.49967 -20.81733 13.06426 1.000 42.66401  ? 84  GLU   A O    1 
ATOM   1258 C CB   . GLU   A 1 87  ? 25.79197 -21.20745 15.69514 1.000 41.41116  ? 84  GLU   A CB   1 
ATOM   1259 C CG   . GLU   A 1 87  ? 26.60105 -22.10442 16.61047 1.000 39.55208  ? 84  GLU   A CG   1 
ATOM   1260 C CD   . GLU   A 1 87  ? 25.96792 -22.23037 17.98755 1.000 60.48140  ? 84  GLU   A CD   1 
ATOM   1261 O OE1  . GLU   A 1 87  ? 24.82116 -21.75610 18.16060 1.000 65.06053  ? 84  GLU   A OE1  1 
ATOM   1262 O OE2  . GLU   A 1 87  ? 26.62006 -22.78686 18.89863 1.000 82.72137  ? 84  GLU   A OE2  1 
ATOM   1263 H H    . GLU   A 1 87  ? 27.57861 -19.51706 15.31307 1.000 33.04590  ? 84  GLU   A H    1 
ATOM   1264 H HA   . GLU   A 1 87  ? 26.77070 -21.67663 13.95220 1.000 37.02618  ? 84  GLU   A HA   1 
ATOM   1265 H HB2  . GLU   A 1 87  ? 25.60780 -20.38642 16.17772 1.000 49.71205  ? 84  GLU   A HB2  1 
ATOM   1266 H HB3  . GLU   A 1 87  ? 24.96193 -21.66713 15.49359 1.000 49.71205  ? 84  GLU   A HB3  1 
ATOM   1267 H HG2  . GLU   A 1 87  ? 26.65776 -22.99072 16.22040 1.000 47.48115  ? 84  GLU   A HG2  1 
ATOM   1268 H HG3  . GLU   A 1 87  ? 27.49015 -21.73187 16.71824 1.000 47.48115  ? 84  GLU   A HG3  1 
ATOM   1269 N N    . SER   A 1 88  ? 25.68951 -18.91388 13.10712 1.000 24.19617  ? 85  SER   A N    1 
ATOM   1270 C CA   . SER   A 1 88  ? 24.68706 -18.14446 12.38835 1.000 27.91938  ? 85  SER   A CA   1 
ATOM   1271 C C    . SER   A 1 88  ? 24.87036 -18.29455 10.88808 1.000 32.35115  ? 85  SER   A C    1 
ATOM   1272 O O    . SER   A 1 88  ? 25.95169 -18.02874 10.35579 1.000 26.78982  ? 85  SER   A O    1 
ATOM   1273 C CB   . SER   A 1 88  ? 24.75603 -16.67005 12.76901 1.000 29.70839  ? 85  SER   A CB   1 
ATOM   1274 O OG   . SER   A 1 88  ? 24.07699 -15.89164 11.80502 1.000 27.81224  ? 85  SER   A OG   1 
ATOM   1275 H H    . SER   A 1 88  ? 26.41193 -18.47869 13.27536 1.000 29.05406  ? 85  SER   A H    1 
ATOM   1276 H HA   . SER   A 1 88  ? 23.81065 -18.48689 12.62405 1.000 33.52191  ? 85  SER   A HA   1 
ATOM   1277 H HB2  . SER   A 1 88  ? 24.33680 -16.54367 13.63455 1.000 35.66873  ? 85  SER   A HB2  1 
ATOM   1278 H HB3  . SER   A 1 88  ? 25.68486 -16.39299 12.80664 1.000 35.66873  ? 85  SER   A HB3  1 
ATOM   1279 H HG   . SER   A 1 88  ? 24.13116 -15.07721 12.00342 1.000 33.39335  ? 85  SER   A HG   1 
ATOM   1280 N N    . ALA   A 1 89  ? 23.79918 -18.71099 10.20910 1.000 31.03578  ? 86  ALA   A N    1 
ATOM   1281 C CA   . ALA   A 1 89  ? 23.82665 -18.78797 8.75068  1.000 34.10112  ? 86  ALA   A CA   1 
ATOM   1282 C C    . ALA   A 1 89  ? 23.90507 -17.41079 8.11733  1.000 28.06394  ? 86  ALA   A C    1 
ATOM   1283 O O    . ALA   A 1 89  ? 24.52362 -17.24546 7.05679  1.000 26.91572  ? 86  ALA   A O    1 
ATOM   1284 C CB   . ALA   A 1 89  ? 22.58147 -19.51470 8.24353  1.000 39.22814  ? 86  ALA   A CB   1 
ATOM   1285 H H    . ALA   A 1 89  ? 23.05418 -18.95142 10.56514 1.000 37.26159  ? 86  ALA   A H    1 
ATOM   1286 H HA   . ALA   A 1 89  ? 24.61069 -19.29277 8.48354  1.000 40.94000  ? 86  ALA   A HA   1 
ATOM   1287 H HB1  . ALA   A 1 89  ? 22.63144 -19.59050 7.27779  1.000 47.09242  ? 86  ALA   A HB1  1 
ATOM   1288 H HB2  . ALA   A 1 89  ? 22.54646 -20.39781 8.64327  1.000 47.09242  ? 86  ALA   A HB2  1 
ATOM   1289 H HB3  . ALA   A 1 89  ? 21.79464 -19.00629 8.49515  1.000 47.09242  ? 86  ALA   A HB3  1 
ATOM   1290 N N    . ALA   A 1 90  ? 23.27582 -16.41092 8.73878  1.000 32.57445  ? 87  ALA   A N    1 
ATOM   1291 C CA   . ALA   A 1 90  ? 23.36344 -15.05707 8.20809  1.000 30.61135  ? 87  ALA   A CA   1 
ATOM   1292 C C    . ALA   A 1 90  ? 24.80452 -14.56050 8.20214  1.000 39.00407  ? 87  ALA   A C    1 
ATOM   1293 O O    . ALA   A 1 90  ? 25.22537 -13.86174 7.27449  1.000 32.81176  ? 87  ALA   A O    1 
ATOM   1294 C CB   . ALA   A 1 90  ? 22.47958 -14.11482 9.02362  1.000 43.46586  ? 87  ALA   A CB   1 
ATOM   1295 H H    . ALA   A 1 90  ? 22.80315 -16.49084 9.45279  1.000 39.10800  ? 87  ALA   A H    1 
ATOM   1296 H HA   . ALA   A 1 90  ? 23.03931 -15.05918 7.29385  1.000 36.75227  ? 87  ALA   A HA   1 
ATOM   1297 H HB1  . ALA   A 1 90  ? 22.53849 -13.22243 8.64802  1.000 52.17769  ? 87  ALA   A HB1  1 
ATOM   1298 H HB2  . ALA   A 1 90  ? 21.56293 -14.42981 8.98571  1.000 52.17769  ? 87  ALA   A HB2  1 
ATOM   1299 H HB3  . ALA   A 1 90  ? 22.78922 -14.10791 9.94284  1.000 52.17769  ? 87  ALA   A HB3  1 
ATOM   1300 N N    . VAL   A 1 91  ? 25.57992 -14.90427 9.23141  1.000 28.40123  ? 88  VAL   A N    1 
ATOM   1301 C CA   . VAL   A 1 91  ? 26.96719 -14.45812 9.25704  1.000 28.51044  ? 88  VAL   A CA   1 
ATOM   1302 C C    . VAL   A 1 91  ? 27.74797 -15.14538 8.15025  1.000 23.97666  ? 88  VAL   A C    1 
ATOM   1303 O O    . VAL   A 1 91  ? 28.57973 -14.52262 7.47865  1.000 25.57402  ? 88  VAL   A O    1 
ATOM   1304 C CB   . VAL   A 1 91  ? 27.59449 -14.71492 10.63916 1.000 27.95577  ? 88  VAL   A CB   1 
ATOM   1305 C CG1  . VAL   A 1 91  ? 29.07265 -14.40062 10.61885 1.000 27.03774  ? 88  VAL   A CG1  1 
ATOM   1306 C CG2  . VAL   A 1 91  ? 26.89119 -13.87633 11.69328 1.000 33.73863  ? 88  VAL   A CG2  1 
ATOM   1307 H H    . VAL   A 1 91  ? 25.33325 -15.37955 9.90436  1.000 34.10013  ? 88  VAL   A H    1 
ATOM   1308 H HA   . VAL   A 1 91  ? 26.98993 -13.50101 9.10112  1.000 34.23118  ? 88  VAL   A HA   1 
ATOM   1309 H HB   . VAL   A 1 91  ? 27.48849 -15.65225 10.86517 1.000 33.56558  ? 88  VAL   A HB   1 
ATOM   1310 H HG11 . VAL   A 1 91  ? 29.41115 -14.41530 11.52775 1.000 32.46394  ? 88  VAL   A HG11 1 
ATOM   1311 H HG12 . VAL   A 1 91  ? 29.53022 -15.06856 10.08463 1.000 32.46394  ? 88  VAL   A HG12 1 
ATOM   1312 H HG13 . VAL   A 1 91  ? 29.20318 -13.52098 10.23143 1.000 32.46394  ? 88  VAL   A HG13 1 
ATOM   1313 H HG21 . VAL   A 1 91  ? 27.29165 -14.05566 12.55837 1.000 40.50501  ? 88  VAL   A HG21 1 
ATOM   1314 H HG22 . VAL   A 1 91  ? 26.99290 -12.93791 11.46984 1.000 40.50501  ? 88  VAL   A HG22 1 
ATOM   1315 H HG23 . VAL   A 1 91  ? 25.95053 -14.11258 11.70886 1.000 40.50501  ? 88  VAL   A HG23 1 
ATOM   1316 N N    . LYS   A 1 92  ? 27.49229 -16.44326 7.94120  1.000 30.20580  ? 89  LYS   A N    1 
ATOM   1317 C CA   . LYS   A 1 92  ? 28.16111 -17.16873 6.86763  1.000 28.67469  ? 89  LYS   A CA   1 
ATOM   1318 C C    . LYS   A 1 92  ? 27.95840 -16.45866 5.53716  1.000 30.01420  ? 89  LYS   A C    1 
ATOM   1319 O O    . LYS   A 1 92  ? 28.91437 -16.21508 4.79541  1.000 28.46320  ? 89  LYS   A O    1 
ATOM   1320 C CB   . LYS   A 1 92  ? 27.63391 -18.60574 6.79353  1.000 29.22950  ? 89  LYS   A CB   1 
ATOM   1321 C CG   . LYS   A 1 92  ? 28.46728 -19.52670 5.89818  1.000 34.73515  ? 89  LYS   A CG   1 
ATOM   1322 C CD   . LYS   A 1 92  ? 27.87861 -20.94894 5.77889  1.000 43.40222  ? 89  LYS   A CD   1 
ATOM   1323 C CE   . LYS   A 1 92  ? 27.56488 -21.61534 7.13483  1.000 74.21879  ? 89  LYS   A CE   1 
ATOM   1324 N NZ   . LYS   A 1 92  ? 28.75356 -21.98868 7.97578  1.000 44.45371  ? 89  LYS   A NZ   1 
ATOM   1325 H H    . LYS   A 1 92  ? 26.94244 -16.91636 8.40320  1.000 36.26562  ? 89  LYS   A H    1 
ATOM   1326 H HA   . LYS   A 1 92  ? 29.11159 -17.20947 7.05691  1.000 34.42828  ? 89  LYS   A HA   1 
ATOM   1327 H HB2  . LYS   A 1 92  ? 27.63329 -18.98351 7.68695  1.000 35.09405  ? 89  LYS   A HB2  1 
ATOM   1328 H HB3  . LYS   A 1 92  ? 26.73074 -18.58810 6.44017  1.000 35.09405  ? 89  LYS   A HB3  1 
ATOM   1329 H HG2  . LYS   A 1 92  ? 28.51002 -19.14592 5.00707  1.000 41.70084  ? 89  LYS   A HG2  1 
ATOM   1330 H HG3  . LYS   A 1 92  ? 29.36020 -19.60368 6.26923  1.000 41.70084  ? 89  LYS   A HG3  1 
ATOM   1331 H HD2  . LYS   A 1 92  ? 27.05066 -20.90223 5.27569  1.000 52.10132  ? 89  LYS   A HD2  1 
ATOM   1332 H HD3  . LYS   A 1 92  ? 28.51739 -21.51262 5.31506  1.000 52.10132  ? 89  LYS   A HD3  1 
ATOM   1333 H HE2  . LYS   A 1 92  ? 27.02629 -21.00112 7.65785  1.000 89.08121  ? 89  LYS   A HE2  1 
ATOM   1334 H HE3  . LYS   A 1 92  ? 27.06757 -22.43062 6.96486  1.000 89.08121  ? 89  LYS   A HE3  1 
ATOM   1335 H HZ1  . LYS   A 1 92  ? 29.46237 -21.50946 7.73074  1.000 53.36311  ? 89  LYS   A HZ1  1 
ATOM   1336 H HZ2  . LYS   A 1 92  ? 28.58075 -21.83048 8.83439  1.000 53.36311  ? 89  LYS   A HZ2  1 
ATOM   1337 H HZ3  . LYS   A 1 92  ? 28.93970 -22.85292 7.87308  1.000 53.36311  ? 89  LYS   A HZ3  1 
ATOM   1338 N N    . GLU   A 1 93  ? 26.71330 -16.08290 5.24108  1.000 28.24334  ? 90  GLU   A N    1 
ATOM   1339 C CA   . GLU   A 1 93  ? 26.41525 -15.44851 3.96118  1.000 33.54957  ? 90  GLU   A CA   1 
ATOM   1340 C C    . GLU   A 1 93  ? 27.14416 -14.11877 3.83031  1.000 32.65385  ? 90  GLU   A C    1 
ATOM   1341 O O    . GLU   A 1 93  ? 27.73846 -13.82278 2.78490  1.000 30.16740  ? 90  GLU   A O    1 
ATOM   1342 C CB   . GLU   A 1 93  ? 24.90097 -15.27632 3.82520  1.000 36.21785  ? 90  GLU   A CB   1 
ATOM   1343 C CG   . GLU   A 1 93  ? 24.43176 -14.55064 2.57457  1.000 96.84922  ? 90  GLU   A CG   1 
ATOM   1344 C CD   . GLU   A 1 93  ? 22.91768 -14.37499 2.53954  1.000 101.71851 ? 90  GLU   A CD   1 
ATOM   1345 O OE1  . GLU   A 1 93  ? 22.22708 -15.02389 3.35652  1.000 66.11558  ? 90  GLU   A OE1  1 
ATOM   1346 O OE2  . GLU   A 1 93  ? 22.42120 -13.58726 1.70212  1.000 101.67887 ? 90  GLU   A OE2  1 
ATOM   1347 H H    . GLU   A 1 93  ? 26.03297 -16.18299 5.75754  1.000 33.91066  ? 90  GLU   A H    1 
ATOM   1348 H HA   . GLU   A 1 93  ? 26.71650 -16.01441 3.23323  1.000 40.27814  ? 90  GLU   A HA   1 
ATOM   1349 H HB2  . GLU   A 1 93  ? 24.49381 -16.15669 3.81740  1.000 43.48008  ? 90  GLU   A HB2  1 
ATOM   1350 H HB3  . GLU   A 1 93  ? 24.58221 -14.77013 4.58879  1.000 43.48008  ? 90  GLU   A HB3  1 
ATOM   1351 H HG2  . GLU   A 1 93  ? 24.83825 -13.67036 2.54677  1.000 116.23772 ? 90  GLU   A HG2  1 
ATOM   1352 H HG3  . GLU   A 1 93  ? 24.69423 -15.06208 1.79326  1.000 116.23772 ? 90  GLU   A HG3  1 
ATOM   1353 N N    . ILE   A 1 94  ? 27.14225 -13.32198 4.89649  1.000 31.68003  ? 91  ILE   A N    1 
ATOM   1354 C CA   . ILE   A 1 94  ? 27.80669 -12.02270 4.86506  1.000 24.02491  ? 91  ILE   A CA   1 
ATOM   1355 C C    . ILE   A 1 94  ? 29.30042 -12.18967 4.62820  1.000 27.98501  ? 91  ILE   A C    1 
ATOM   1356 O O    . ILE   A 1 94  ? 29.89854 -11.48458 3.80460  1.000 26.75036  ? 91  ILE   A O    1 
ATOM   1357 C CB   . ILE   A 1 94  ? 27.52844 -11.25333 6.17209  1.000 33.39601  ? 91  ILE   A CB   1 
ATOM   1358 C CG1  . ILE   A 1 94  ? 26.08250 -10.76100 6.18748  1.000 46.92274  ? 91  ILE   A CG1  1 
ATOM   1359 C CG2  . ILE   A 1 94  ? 28.49665 -10.09646 6.33445  1.000 35.87479  ? 91  ILE   A CG2  1 
ATOM   1360 C CD1  . ILE   A 1 94  ? 25.60110 -10.30950 7.55520  1.000 40.43023  ? 91  ILE   A CD1  1 
ATOM   1361 H H    . ILE   A 1 94  ? 26.76546 -13.50885 5.64663  1.000 38.03469  ? 91  ILE   A H    1 
ATOM   1362 H HA   . ILE   A 1 94  ? 27.44531 -11.51073 4.12467  1.000 28.84855  ? 91  ILE   A HA   1 
ATOM   1363 H HB   . ILE   A 1 94  ? 27.65953 -11.85701 6.91995  1.000 40.09387  ? 91  ILE   A HB   1 
ATOM   1364 H HG12 . ILE   A 1 94  ? 26.00396 -10.00668 5.58273  1.000 56.32595  ? 91  ILE   A HG12 1 
ATOM   1365 H HG13 . ILE   A 1 94  ? 25.50466 -11.48284 5.89429  1.000 56.32595  ? 91  ILE   A HG13 1 
ATOM   1366 H HG21 . ILE   A 1 94  ? 28.12839 -9.46333  6.97040  1.000 43.06840  ? 91  ILE   A HG21 1 
ATOM   1367 H HG22 . ILE   A 1 94  ? 29.34431 -10.43742 6.66021  1.000 43.06840  ? 91  ILE   A HG22 1 
ATOM   1368 H HG23 . ILE   A 1 94  ? 28.62180 -9.66627  5.47411  1.000 43.06840  ? 91  ILE   A HG23 1 
ATOM   1369 H HD11 . ILE   A 1 94  ? 24.64465 -10.15243 7.51735  1.000 48.53493  ? 91  ILE   A HD11 1 
ATOM   1370 H HD12 . ILE   A 1 94  ? 25.79692 -11.00357 8.20389  1.000 48.53493  ? 91  ILE   A HD12 1 
ATOM   1371 H HD13 . ILE   A 1 94  ? 26.06141 -9.49080  7.79759  1.000 48.53493  ? 91  ILE   A HD13 1 
ATOM   1372 N N    . LEU   A 1 95  ? 29.93176 -13.10858 5.36260  1.000 26.38202  ? 92  LEU   A N    1 
ATOM   1373 C CA   . LEU   A 1 95  ? 31.37396 -13.27068 5.23052  1.000 24.83214  ? 92  LEU   A CA   1 
ATOM   1374 C C    . LEU   A 1 95  ? 31.75369 -13.82531 3.86066  1.000 24.85742  ? 92  LEU   A C    1 
ATOM   1375 O O    . LEU   A 1 95  ? 32.73127 -13.36857 3.25347  1.000 27.15156  ? 92  LEU   A O    1 
ATOM   1376 C CB   . LEU   A 1 95  ? 31.90753 -14.17489 6.33523  1.000 28.92898  ? 92  LEU   A CB   1 
ATOM   1377 C CG   . LEU   A 1 95  ? 31.75756 -13.64778 7.76755  1.000 28.68524  ? 92  LEU   A CG   1 
ATOM   1378 C CD1  . LEU   A 1 95  ? 32.21514 -14.69715 8.76326  1.000 30.82971  ? 92  LEU   A CD1  1 
ATOM   1379 C CD2  . LEU   A 1 95  ? 32.54316 -12.35983 7.93025  1.000 29.89166  ? 92  LEU   A CD2  1 
ATOM   1380 H H    A LEU   A 1 95  ? 29.55590 -13.63555 5.92883  0.650 31.67708  ? 92  LEU   A H    1 
ATOM   1381 H H    B LEU   A 1 95  ? 29.55590 -13.63555 5.92883  0.350 31.67708  ? 92  LEU   A H    1 
ATOM   1382 H HA   . LEU   A 1 95  ? 31.78866 -12.39911 5.32691  1.000 29.81722  ? 92  LEU   A HA   1 
ATOM   1383 H HB2  . LEU   A 1 95  ? 31.43375 -15.02007 6.28930  1.000 34.73343  ? 92  LEU   A HB2  1 
ATOM   1384 H HB3  . LEU   A 1 95  ? 32.85436 -14.31642 6.17909  1.000 34.73343  ? 92  LEU   A HB3  1 
ATOM   1385 H HG   . LEU   A 1 95  ? 30.82474 -13.45468 7.95043  1.000 34.44095  ? 92  LEU   A HG   1 
ATOM   1386 H HD11 . LEU   A 1 95  ? 32.10311 -14.34984 9.66199  1.000 37.01431  ? 92  LEU   A HD11 1 
ATOM   1387 H HD12 . LEU   A 1 95  ? 31.67831 -15.49685 8.64837  1.000 37.01431  ? 92  LEU   A HD12 1 
ATOM   1388 H HD13 . LEU   A 1 95  ? 33.14974 -14.90003 8.60116  1.000 37.01431  ? 92  LEU   A HD13 1 
ATOM   1389 H HD21 . LEU   A 1 95  ? 32.58908 -12.13484 8.87268  1.000 35.88865  ? 92  LEU   A HD21 1 
ATOM   1390 H HD22 . LEU   A 1 95  ? 33.43731 -12.48854 7.57696  1.000 35.88865  ? 92  LEU   A HD22 1 
ATOM   1391 H HD23 . LEU   A 1 95  ? 32.09358 -11.65196 7.44271  1.000 35.88865  ? 92  LEU   A HD23 1 
ATOM   1392 N N    A LYS   A 1 96  ? 31.00431 -14.81353 3.36026  0.473 31.93041  ? 93  LYS   A N    1 
ATOM   1393 N N    B LYS   A 1 96  ? 31.01184 -14.81786 3.35942  0.527 31.96426  ? 93  LYS   A N    1 
ATOM   1394 C CA   A LYS   A 1 96  ? 31.31416 -15.36720 2.04344  0.473 27.55174  ? 93  LYS   A CA   1 
ATOM   1395 C CA   B LYS   A 1 96  ? 31.32545 -15.36035 2.03835  0.527 27.62969  ? 93  LYS   A CA   1 
ATOM   1396 C C    A LYS   A 1 96  ? 31.19447 -14.29857 0.96364  0.473 27.39482  ? 93  LYS   A C    1 
ATOM   1397 C C    B LYS   A 1 96  ? 31.21444 -14.27395 0.97526  0.527 27.55362  ? 93  LYS   A C    1 
ATOM   1398 O O    A LYS   A 1 96  ? 32.05881 -14.18982 0.08763  0.473 36.07635  ? 93  LYS   A O    1 
ATOM   1399 O O    B LYS   A 1 96  ? 32.09822 -14.12580 0.12491  0.527 35.87779  ? 93  LYS   A O    1 
ATOM   1400 C CB   A LYS   A 1 96  ? 30.40301 -16.55782 1.73667  0.473 33.41464  ? 93  LYS   A CB   1 
ATOM   1401 C CB   B LYS   A 1 96  ? 30.41064 -16.53930 1.70412  0.527 33.41655  ? 93  LYS   A CB   1 
ATOM   1402 C CG   A LYS   A 1 96  ? 30.72471 -17.81164 2.56010  0.473 50.54315  ? 93  LYS   A CG   1 
ATOM   1403 C CG   B LYS   A 1 96  ? 30.95112 -17.90882 2.14529  0.527 54.07581  ? 93  LYS   A CG   1 
ATOM   1404 C CD   A LYS   A 1 96  ? 30.02609 -19.06054 2.02663  0.473 55.27666  ? 93  LYS   A CD   1 
ATOM   1405 C CD   B LYS   A 1 96  ? 32.22867 -18.30701 1.39123  0.527 67.45870  ? 93  LYS   A CD   1 
ATOM   1406 C CE   A LYS   A 1 96  ? 30.40654 -20.31014 2.82947  0.473 62.77149  ? 93  LYS   A CE   1 
ATOM   1407 C CE   B LYS   A 1 96  ? 32.83803 -19.60546 1.93762  0.527 47.05643  ? 93  LYS   A CE   1 
ATOM   1408 N NZ   A LYS   A 1 96  ? 31.83623 -20.71019 2.65691  0.473 48.93678  ? 93  LYS   A NZ   1 
ATOM   1409 N NZ   B LYS   A 1 96  ? 34.26572 -19.78872 1.51591  0.527 40.28910  ? 93  LYS   A NZ   1 
ATOM   1410 H H    A LYS   A 1 96  ? 30.32852 -15.17091 3.75422  0.473 38.33514  ? 93  LYS   A H    1 
ATOM   1411 H H    B LYS   A 1 96  ? 30.34081 -15.18358 3.75382  0.527 38.37577  ? 93  LYS   A H    1 
ATOM   1412 H HA   A LYS   A 1 96  ? 32.22754 -15.69373 2.04649  0.473 33.08075  ? 93  LYS   A HA   1 
ATOM   1413 H HA   B LYS   A 1 96  ? 32.23579 -15.69516 2.04814  0.527 33.17428  ? 93  LYS   A HA   1 
ATOM   1414 H HB2  A LYS   A 1 96  ? 29.48595 -16.30573 1.92734  0.473 40.11622  ? 93  LYS   A HB2  1 
ATOM   1415 H HB2  B LYS   A 1 96  ? 29.55810 -16.40417 2.14663  0.527 40.11852  ? 93  LYS   A HB2  1 
ATOM   1416 H HB3  A LYS   A 1 96  ? 30.49575 -16.78774 0.79889  0.473 40.11622  ? 93  LYS   A HB3  1 
ATOM   1417 H HB3  B LYS   A 1 96  ? 30.28435 -16.56974 0.74286  0.527 40.11852  ? 93  LYS   A HB3  1 
ATOM   1418 H HG2  A LYS   A 1 96  ? 31.68144 -17.96970 2.53616  0.473 60.67044  ? 93  LYS   A HG2  1 
ATOM   1419 H HG2  B LYS   A 1 96  ? 31.15820 -17.87833 3.09243  0.527 64.90962  ? 93  LYS   A HG2  1 
ATOM   1420 H HG3  A LYS   A 1 96  ? 30.43414 -17.67307 3.47513  0.473 60.67044  ? 93  LYS   A HG3  1 
ATOM   1421 H HG3  B LYS   A 1 96  ? 30.27783 -18.58588 1.97452  0.527 64.90962  ? 93  LYS   A HG3  1 
ATOM   1422 H HD2  A LYS   A 1 96  ? 29.06541 -18.94102 2.08747  0.473 66.35065  ? 93  LYS   A HD2  1 
ATOM   1423 H HD2  B LYS   A 1 96  ? 32.01735 -18.44263 0.45429  0.527 80.96910  ? 93  LYS   A HD2  1 
ATOM   1424 H HD3  A LYS   A 1 96  ? 30.28488 -19.20249 1.10263  0.473 66.35065  ? 93  LYS   A HD3  1 
ATOM   1425 H HD3  B LYS   A 1 96  ? 32.88740 -17.60104 1.48394  0.527 80.96910  ? 93  LYS   A HD3  1 
ATOM   1426 H HE2  A LYS   A 1 96  ? 30.25814 -20.13546 3.77200  0.473 75.34444  ? 93  LYS   A HE2  1 
ATOM   1427 H HE2  B LYS   A 1 96  ? 32.81043 -19.58597 2.90704  0.527 56.48637  ? 93  LYS   A HE2  1 
ATOM   1428 H HE3  A LYS   A 1 96  ? 29.85291 -21.05149 2.53827  0.473 75.34444  ? 93  LYS   A HE3  1 
ATOM   1429 H HE3  B LYS   A 1 96  ? 32.32682 -20.36030 1.60628  0.527 56.48637  ? 93  LYS   A HE3  1 
ATOM   1430 H HZ1  A LYS   A 1 96  ? 32.00958 -21.43670 3.14089  0.473 58.74279  ? 93  LYS   A HZ1  1 
ATOM   1431 H HZ1  B LYS   A 1 96  ? 34.58787 -20.54669 1.85325  0.527 48.36558  ? 93  LYS   A HZ1  1 
ATOM   1432 H HZ2  A LYS   A 1 96  ? 32.37116 -20.05088 2.92387  0.473 58.74279  ? 93  LYS   A HZ2  1 
ATOM   1433 H HZ2  B LYS   A 1 96  ? 34.31901 -19.82204 0.62813  0.527 48.36558  ? 93  LYS   A HZ2  1 
ATOM   1434 H HZ3  A LYS   A 1 96  ? 32.00150 -20.88742 1.80054  0.473 58.74279  ? 93  LYS   A HZ3  1 
ATOM   1435 H HZ3  B LYS   A 1 96  ? 34.75952 -19.10900 1.80959  0.527 48.36558  ? 93  LYS   A HZ3  1 
ATOM   1436 N N    . GLU   A 1 97  ? 30.14138 -13.48323 1.02517  1.000 24.52424  ? 94  GLU   A N    1 
ATOM   1437 C CA   . GLU   A 1 97  ? 30.00084 -12.39078 0.07190  1.000 34.19561  ? 94  GLU   A CA   1 
ATOM   1438 C C    . GLU   A 1 97  ? 31.15583 -11.40986 0.19579  1.000 39.61073  ? 94  GLU   A C    1 
ATOM   1439 O O    . GLU   A 1 97  ? 31.66629 -10.90878 -0.81271 1.000 30.04097  ? 94  GLU   A O    1 
ATOM   1440 C CB   . GLU   A 1 97  ? 28.66975 -11.67142 0.28398  1.000 35.03500  ? 94  GLU   A CB   1 
ATOM   1441 C CG   . GLU   A 1 97  ? 28.53677 -10.36108 -0.48655 1.000 70.00467  ? 94  GLU   A CG   1 
ATOM   1442 C CD   . GLU   A 1 97  ? 27.36624 -9.52467  -0.00474 1.000 92.07984  ? 94  GLU   A CD   1 
ATOM   1443 O OE1  . GLU   A 1 97  ? 26.39215 -10.11589 0.51552  1.000 72.33960  ? 94  GLU   A OE1  1 
ATOM   1444 O OE2  . GLU   A 1 97  ? 27.43045 -8.28195  -0.13372 1.000 90.87211  ? 94  GLU   A OE2  1 
ATOM   1445 H H    A GLU   A 1 97  ? 29.50524 -13.54172 1.60094  0.473 29.44774  ? 94  GLU   A H    1 
ATOM   1446 H H    B GLU   A 1 97  ? 29.49647 -13.55816 1.58915  0.527 29.44774  ? 94  GLU   A H    1 
ATOM   1447 H HA   . GLU   A 1 97  ? 30.00353 -12.75777 -0.82599 1.000 41.05339  ? 94  GLU   A HA   1 
ATOM   1448 H HB2  . GLU   A 1 97  ? 27.95179 -12.25646 -0.00442 1.000 42.06065  ? 94  GLU   A HB2  1 
ATOM   1449 H HB3  . GLU   A 1 97  ? 28.57377 -11.46880 1.22771  1.000 42.06065  ? 94  GLU   A HB3  1 
ATOM   1450 H HG2  . GLU   A 1 97  ? 29.34720 -9.84081  -0.37072 1.000 84.02426  ? 94  GLU   A HG2  1 
ATOM   1451 H HG3  . GLU   A 1 97  ? 28.40030 -10.55777 -1.42654 1.000 84.02426  ? 94  GLU   A HG3  1 
ATOM   1452 N N    . GLN   A 1 98  ? 31.56654 -11.10227 1.42752  1.000 30.49731  ? 95  GLN   A N    1 
ATOM   1453 C CA   . GLN   A 1 98  ? 32.65878 -10.15300 1.61962  1.000 29.83463  ? 95  GLN   A CA   1 
ATOM   1454 C C    . GLN   A 1 98  ? 33.96523 -10.71348 1.07160  1.000 33.82538  ? 95  GLN   A C    1 
ATOM   1455 O O    . GLN   A 1 98  ? 34.74743 -9.99117  0.44174  1.000 31.30319  ? 95  GLN   A O    1 
ATOM   1456 C CB   . GLN   A 1 98  ? 32.78676 -9.81016  3.10456  1.000 33.95435  ? 95  GLN   A CB   1 
ATOM   1457 C CG   . GLN   A 1 98  ? 33.82347 -8.74200  3.41216  1.000 30.10109  ? 95  GLN   A CG   1 
ATOM   1458 C CD   . GLN   A 1 98  ? 33.36235 -7.33176  3.06377  1.000 40.34400  ? 95  GLN   A CD   1 
ATOM   1459 O OE1  . GLN   A 1 98  ? 32.38173 -7.13745  2.34166  1.000 32.53863  ? 95  GLN   A OE1  1 
ATOM   1460 N NE2  . GLN   A 1 98  ? 34.07208 -6.33879  3.58661  1.000 30.00914  ? 95  GLN   A NE2  1 
ATOM   1461 H H    . GLN   A 1 98  ? 31.23555 -11.42333 2.15344  1.000 36.61542  ? 95  GLN   A H    1 
ATOM   1462 H HA   . GLN   A 1 98  ? 32.46352 -9.33200  1.14136  1.000 35.82021  ? 95  GLN   A HA   1 
ATOM   1463 H HB2  . GLN   A 1 98  ? 31.92914 -9.48779  3.42310  1.000 40.76388  ? 95  GLN   A HB2  1 
ATOM   1464 H HB3  . GLN   A 1 98  ? 33.03955 -10.61274 3.58712  1.000 40.76388  ? 95  GLN   A HB3  1 
ATOM   1465 H HG2  . GLN   A 1 98  ? 34.02344 -8.76324  4.36108  1.000 36.13996  ? 95  GLN   A HG2  1 
ATOM   1466 H HG3  . GLN   A 1 98  ? 34.62599 -8.92722  2.89976  1.000 36.13996  ? 95  GLN   A HG3  1 
ATOM   1467 H HE21 . GLN   A 1 98  ? 34.74808 -6.51167  4.08934  1.000 36.02962  ? 95  GLN   A HE21 1 
ATOM   1468 H HE22 . GLN   A 1 98  ? 33.85576 -5.52278  3.42252  1.000 36.02962  ? 95  GLN   A HE22 1 
ATOM   1469 N N    . GLU   A 1 99  ? 34.21395 -12.00184 1.29579  1.000 27.07332  ? 96  GLU   A N    1 
ATOM   1470 C CA   . GLU   A 1 99  ? 35.39760 -12.63018 0.71990  1.000 35.76047  ? 96  GLU   A CA   1 
ATOM   1471 C C    . GLU   A 1 99  ? 35.36859 -12.55701 -0.80427 1.000 40.73495  ? 96  GLU   A C    1 
ATOM   1472 O O    . GLU   A 1 99  ? 36.37367 -12.20784 -1.43137 1.000 32.72444  ? 96  GLU   A O    1 
ATOM   1473 C CB   . GLU   A 1 99  ? 35.49307 -14.07612 1.20739  1.000 35.22723  ? 96  GLU   A CB   1 
ATOM   1474 C CG   . GLU   A 1 99  ? 36.82171 -14.76576 0.92570  1.000 44.05614  ? 96  GLU   A CG   1 
ATOM   1475 C CD   . GLU   A 1 99  ? 36.83528 -16.20864 1.40934  1.000 37.14125  ? 96  GLU   A CD   1 
ATOM   1476 O OE1  . GLU   A 1 99  ? 35.82831 -16.93206 1.21508  1.000 43.63494  ? 96  GLU   A OE1  1 
ATOM   1477 O OE2  . GLU   A 1 99  ? 37.85856 -16.61701 1.98832  1.000 37.93547  ? 96  GLU   A OE2  1 
ATOM   1478 H H    . GLU   A 1 99  ? 33.72213 -12.52492 1.76918  1.000 32.50664  ? 96  GLU   A H    1 
ATOM   1479 H HA   . GLU   A 1 99  ? 36.19375 -12.16287 1.01766  1.000 42.93122  ? 96  GLU   A HA   1 
ATOM   1480 H HB2  . GLU   A 1 99  ? 35.35882 -14.08541 2.16801  1.000 42.29133  ? 96  GLU   A HB2  1 
ATOM   1481 H HB3  . GLU   A 1 99  ? 34.79872 -14.59360 0.77035  1.000 42.29133  ? 96  GLU   A HB3  1 
ATOM   1482 H HG2  . GLU   A 1 99  ? 36.98350 -14.76610 -0.03072 1.000 52.88603  ? 96  GLU   A HG2  1 
ATOM   1483 H HG3  . GLU   A 1 99  ? 37.53150 -14.28740 1.38207  1.000 52.88603  ? 96  GLU   A HG3  1 
ATOM   1484 N N    . ASN   A 1 100 ? 34.20491 -12.82547 -1.41288 1.000 32.53297  ? 97  ASN   A N    1 
ATOM   1485 C CA   . ASN   A 1 100 ? 34.11625 -12.85852 -2.86853 1.000 42.62138  ? 97  ASN   A CA   1 
ATOM   1486 C C    . ASN   A 1 100 ? 34.41004 -11.49954 -3.48615 1.000 45.88645  ? 97  ASN   A C    1 
ATOM   1487 O O    . ASN   A 1 100 ? 35.10145 -11.41531 -4.50941 1.000 47.11922  ? 97  ASN   A O    1 
ATOM   1488 C CB   . ASN   A 1 100 ? 32.72923 -13.32782 -3.30759 1.000 35.97333  ? 97  ASN   A CB   1 
ATOM   1489 C CG   . ASN   A 1 100 ? 32.58612 -14.82798 -3.26148 1.000 75.50300  ? 97  ASN   A CG   1 
ATOM   1490 O OD1  . ASN   A 1 100 ? 33.55566 -15.56246 -3.45080 1.000 79.66099  ? 97  ASN   A OD1  1 
ATOM   1491 N ND2  . ASN   A 1 100 ? 31.37119 -15.29724 -3.00498 1.000 80.23381  ? 97  ASN   A ND2  1 
ATOM   1492 H H    . ASN   A 1 100 ? 33.46449 -12.98919 -1.00720 1.000 39.05822  ? 97  ASN   A H    1 
ATOM   1493 H HA   . ASN   A 1 100 ? 34.77733 -13.49143 -3.18992 1.000 51.16432  ? 97  ASN   A HA   1 
ATOM   1494 H HB2  . ASN   A 1 100 ? 32.06276 -12.94358 -2.71676 1.000 43.18665  ? 97  ASN   A HB2  1 
ATOM   1495 H HB3  . ASN   A 1 100 ? 32.57051 -13.03820 -4.21964 1.000 43.18665  ? 97  ASN   A HB3  1 
ATOM   1496 H HD21 . ASN   A 1 100 ? 31.23700 -16.14590 -2.96788 1.000 96.29923  ? 97  ASN   A HD21 1 
ATOM   1497 H HD22 . ASN   A 1 100 ? 30.71826 -14.75261 -2.87589 1.000 96.29923  ? 97  ASN   A HD22 1 
ATOM   1498 N N    . ARG   A 1 101 ? 33.87816 -10.43213 -2.90860 1.000 34.29883  ? 98  ARG   A N    1 
ATOM   1499 C CA   . ARG   A 1 101 ? 34.13323 -9.09784  -3.42960 1.000 31.71056  ? 98  ARG   A CA   1 
ATOM   1500 C C    . ARG   A 1 101 ? 35.43174 -8.50751  -2.90831 1.000 33.03655  ? 98  ARG   A C    1 
ATOM   1501 O O    . ARG   A 1 101 ? 35.68603 -7.31804  -3.11871 1.000 43.34991  ? 98  ARG   A O    1 
ATOM   1502 C CB   . ARG   A 1 101 ? 32.96052 -8.16267  -3.11713 1.000 40.15703  ? 98  ARG   A CB   1 
ATOM   1503 C CG   . ARG   A 1 101 ? 32.62831 -7.97543  -1.66425 1.000 57.47865  ? 98  ARG   A CG   1 
ATOM   1504 C CD   . ARG   A 1 101 ? 31.48109 -6.97697  -1.50194 1.000 52.40184  ? 98  ARG   A CD   1 
ATOM   1505 N NE   . ARG   A 1 101 ? 31.85452 -5.65040  -1.98233 1.000 59.73618  ? 98  ARG   A NE   1 
ATOM   1506 C CZ   . ARG   A 1 101 ? 32.52871 -4.75268  -1.27248 1.000 104.12438 ? 98  ARG   A CZ   1 
ATOM   1507 N NH1  . ARG   A 1 101 ? 32.91626 -5.00027  -0.02855 1.000 50.18381  ? 98  ARG   A NH1  1 
ATOM   1508 N NH2  . ARG   A 1 101 ? 32.82377 -3.57770  -1.82512 1.000 76.28394  ? 98  ARG   A NH2  1 
ATOM   1509 H H    A ARG   A 1 101 ? 33.36815 -10.45470 -2.21652 0.410 41.17725  ? 98  ARG   A H    1 
ATOM   1510 H H    B ARG   A 1 101 ? 33.36815 -10.45470 -2.21652 0.590 41.17725  ? 98  ARG   A H    1 
ATOM   1511 H HA   . ARG   A 1 101 ? 34.20021 -9.15369  -4.39567 1.000 38.07133  ? 98  ARG   A HA   1 
ATOM   1512 H HB2  . ARG   A 1 101 ? 33.16868 -7.28646  -3.47746 1.000 48.20709  ? 98  ARG   A HB2  1 
ATOM   1513 H HB3  . ARG   A 1 101 ? 32.16746 -8.51856  -3.54761 1.000 48.20709  ? 98  ARG   A HB3  1 
ATOM   1514 H HG2  . ARG   A 1 101 ? 32.35621 -8.82392  -1.28093 1.000 68.99304  ? 98  ARG   A HG2  1 
ATOM   1515 H HG3  . ARG   A 1 101 ? 33.40490 -7.63303  -1.19461 1.000 68.99304  ? 98  ARG   A HG3  1 
ATOM   1516 H HD2  . ARG   A 1 101 ? 30.71517 -7.28206  -2.01300 1.000 62.90086  ? 98  ARG   A HD2  1 
ATOM   1517 H HD3  . ARG   A 1 101 ? 31.24693 -6.90674  -0.56325 1.000 62.90086  ? 98  ARG   A HD3  1 
ATOM   1518 H HE   . ARG   A 1 101 ? 31.62156 -5.43467  -2.78158 1.000 71.70207  ? 98  ARG   A HE   1 
ATOM   1519 H HH11 . ARG   A 1 101 ? 32.73195 -5.75670  0.33677  1.000 60.23923  ? 98  ARG   A HH11 1 
ATOM   1520 H HH12 . ARG   A 1 101 ? 33.35188 -4.40440  0.41278  1.000 60.23923  ? 98  ARG   A HH12 1 
ATOM   1521 H HH21 . ARG   A 1 101 ? 32.57824 -3.40810  -2.63168 1.000 91.55938  ? 98  ARG   A HH21 1 
ATOM   1522 H HH22 . ARG   A 1 101 ? 33.25986 -2.98842  -1.37547 1.000 91.55938  ? 98  ARG   A HH22 1 
ATOM   1523 N N    . LYS   A 1 102 ? 36.25611 -9.31552  -2.23818 1.000 39.61291  ? 99  LYS   A N    1 
ATOM   1524 C CA   . LYS   A 1 102 ? 37.59005 -8.89550  -1.79776 1.000 40.91694  ? 99  LYS   A CA   1 
ATOM   1525 C C    . LYS   A 1 102 ? 37.51845 -7.70463  -0.84679 1.000 38.85404  ? 99  LYS   A C    1 
ATOM   1526 O O    . LYS   A 1 102 ? 38.35128 -6.79785  -0.88536 1.000 39.03787  ? 99  LYS   A O    1 
ATOM   1527 C CB   . LYS   A 1 102 ? 38.48227 -8.59296  -3.00308 1.000 51.00266  ? 99  LYS   A CB   1 
ATOM   1528 C CG   . LYS   A 1 102 ? 38.76239 -9.83941  -3.85844 1.000 54.23824  ? 99  LYS   A CG   1 
ATOM   1529 C CD   . LYS   A 1 102 ? 39.26896 -9.49286  -5.24984 1.000 91.10484  ? 99  LYS   A CD   1 
ATOM   1530 C CE   . LYS   A 1 102 ? 40.77710 -9.29957  -5.27784 1.000 103.43740 ? 99  LYS   A CE   1 
ATOM   1531 N NZ   . LYS   A 1 102 ? 41.22494 -8.70490  -6.57211 1.000 117.84562 ? 99  LYS   A NZ   1 
ATOM   1532 H H    . LYS   A 1 102 ? 36.06324 -10.12541 -2.02259 1.000 47.55415  ? 99  LYS   A H    1 
ATOM   1533 H HA   . LYS   A 1 102 ? 37.99477 -9.62225  -1.29883 1.000 49.11898  ? 99  LYS   A HA   1 
ATOM   1534 H HB2  . LYS   A 1 102 ? 38.04306 -7.93507  -3.56448 1.000 61.22184  ? 99  LYS   A HB2  1 
ATOM   1535 H HB3  . LYS   A 1 102 ? 39.33194 -8.24648  -2.68857 1.000 61.22184  ? 99  LYS   A HB3  1 
ATOM   1536 H HG2  . LYS   A 1 102 ? 39.43761 -10.37992 -3.41933 1.000 65.10454  ? 99  LYS   A HG2  1 
ATOM   1537 H HG3  . LYS   A 1 102 ? 37.94210 -10.34787 -3.95582 1.000 65.10454  ? 99  LYS   A HG3  1 
ATOM   1538 H HD2  . LYS   A 1 102 ? 39.04513 -10.21338 -5.85947 1.000 109.34446 ? 99  LYS   A HD2  1 
ATOM   1539 H HD3  . LYS   A 1 102 ? 38.85287 -8.66766  -5.54449 1.000 109.34446 ? 99  LYS   A HD3  1 
ATOM   1540 H HE2  . LYS   A 1 102 ? 41.03817 -8.70156  -4.56012 1.000 124.14353 ? 99  LYS   A HE2  1 
ATOM   1541 H HE3  . LYS   A 1 102 ? 41.21364 -10.15892 -5.16900 1.000 124.14353 ? 99  LYS   A HE3  1 
ATOM   1542 H HZ1  . LYS   A 1 102 ? 42.11354 -8.66083  -6.59555 1.000 141.43340 ? 99  LYS   A HZ1  1 
ATOM   1543 H HZ2  . LYS   A 1 102 ? 40.94260 -9.20607  -7.25124 1.000 141.43340 ? 99  LYS   A HZ2  1 
ATOM   1544 H HZ3  . LYS   A 1 102 ? 40.89259 -7.88410  -6.66114 1.000 141.43340 ? 99  LYS   A HZ3  1 
ATOM   1545 N N    . GLY   A 1 103 ? 36.52269 -7.71730  0.01883  1.000 32.96570  ? 100 GLY   A N    1 
ATOM   1546 C CA   . GLY   A 1 103 ? 36.45284 -6.74448  1.07901  1.000 33.44410  ? 100 GLY   A CA   1 
ATOM   1547 C C    . GLY   A 1 103 ? 37.19586 -7.20834  2.31747  1.000 29.92789  ? 100 GLY   A C    1 
ATOM   1548 O O    . GLY   A 1 103 ? 37.48468 -8.38809  2.49452  1.000 32.52393  ? 100 GLY   A O    1 
ATOM   1549 H H    . GLY   A 1 103 ? 35.87439 -8.28231  0.01091  1.000 39.57750  ? 100 GLY   A H    1 
ATOM   1550 H HA2  . GLY   A 1 103 ? 36.84511 -5.90983  0.77838  1.000 40.15157  ? 100 GLY   A HA2  1 
ATOM   1551 H HA3  . GLY   A 1 103 ? 35.52489 -6.59015  1.31565  1.000 40.15157  ? 100 GLY   A HA3  1 
ATOM   1552 N N    . LEU   A 1 104 ? 37.50107 -6.25536  3.18762  1.000 28.68398  ? 101 LEU   A N    1 
ATOM   1553 C CA   . LEU   A 1 104 ? 38.25422 -6.54140  4.39455  1.000 25.48239  ? 101 LEU   A CA   1 
ATOM   1554 C C    . LEU   A 1 104 ? 37.38273 -7.23675  5.43053  1.000 22.09385  ? 101 LEU   A C    1 
ATOM   1555 O O    . LEU   A 1 104 ? 36.19907 -6.90888  5.60303  1.000 21.89806  ? 101 LEU   A O    1 
ATOM   1556 C CB   . LEU   A 1 104 ? 38.82312 -5.24889  4.96127  1.000 27.25624  ? 101 LEU   A CB   1 
ATOM   1557 C CG   . LEU   A 1 104 ? 39.75629 -5.35218  6.16367  1.000 37.47508  ? 101 LEU   A CG   1 
ATOM   1558 C CD1  . LEU   A 1 104 ? 40.96396 -6.18356  5.79551  1.000 35.88004  ? 101 LEU   A CD1  1 
ATOM   1559 C CD2  . LEU   A 1 104 ? 40.17000 -3.95720  6.62464  1.000 33.36322  ? 101 LEU   A CD2  1 
ATOM   1560 H H    . LEU   A 1 104 ? 37.28086 -5.42871  3.09960  1.000 34.43943  ? 101 LEU   A H    1 
ATOM   1561 H HA   . LEU   A 1 104 ? 38.98944 -7.13910  4.18692  1.000 30.59753  ? 101 LEU   A HA   1 
ATOM   1562 H HB2  . LEU   A 1 104 ? 39.32401 -4.81156  4.25504  1.000 32.72614  ? 101 LEU   A HB2  1 
ATOM   1563 H HB3  . LEU   A 1 104 ? 38.07717 -4.69156  5.23300  1.000 32.72614  ? 101 LEU   A HB3  1 
ATOM   1564 H HG   . LEU   A 1 104 ? 39.30299 -5.78581  6.90352  1.000 44.98875  ? 101 LEU   A HG   1 
ATOM   1565 H HD11 . LEU   A 1 104 ? 41.65385 -6.05191  6.46455  1.000 43.07471  ? 101 LEU   A HD11 1 
ATOM   1566 H HD12 . LEU   A 1 104 ? 40.70656 -7.11830  5.76530  1.000 43.07471  ? 101 LEU   A HD12 1 
ATOM   1567 H HD13 . LEU   A 1 104 ? 41.28834 -5.90152  4.92595  1.000 43.07471  ? 101 LEU   A HD13 1 
ATOM   1568 H HD21 . LEU   A 1 104 ? 40.68767 -4.03504  7.44126  1.000 40.05452  ? 101 LEU   A HD21 1 
ATOM   1569 H HD22 . LEU   A 1 104 ? 40.70628 -3.54162  5.93139  1.000 40.05452  ? 101 LEU   A HD22 1 
ATOM   1570 H HD23 . LEU   A 1 104 ? 39.37284 -3.42905  6.78742  1.000 40.05452  ? 101 LEU   A HD23 1 
ATOM   1571 N N    . ILE   A 1 105 ? 37.96551 -8.23177  6.09279  1.000 23.37291  ? 102 ILE   A N    1 
ATOM   1572 C CA   . ILE   A 1 105 ? 37.33002 -8.94511  7.19116  1.000 25.35761  ? 102 ILE   A CA   1 
ATOM   1573 C C    . ILE   A 1 105 ? 38.25437 -8.83538  8.39149  1.000 27.23397  ? 102 ILE   A C    1 
ATOM   1574 O O    . ILE   A 1 105 ? 39.44714 -9.14518  8.28648  1.000 24.98054  ? 102 ILE   A O    1 
ATOM   1575 C CB   . ILE   A 1 105 ? 37.05888 -10.41489 6.83309  1.000 30.14823  ? 102 ILE   A CB   1 
ATOM   1576 C CG1  . ILE   A 1 105 ? 36.07910 -10.47707 5.65838  1.000 30.47713  ? 102 ILE   A CG1  1 
ATOM   1577 C CG2  . ILE   A 1 105 ? 36.50673 -11.15078 8.02240  1.000 28.90570  ? 102 ILE   A CG2  1 
ATOM   1578 C CD1  . ILE   A 1 105 ? 35.87345 -11.87467 5.10358  1.000 35.18178  ? 102 ILE   A CD1  1 
ATOM   1579 H H    . ILE   A 1 105 ? 38.75635 -8.51983  5.91617  1.000 28.06614  ? 102 ILE   A H    1 
ATOM   1580 H HA   . ILE   A 1 105 ? 36.47958 -8.53281  7.40947  1.000 30.44779  ? 102 ILE   A HA   1 
ATOM   1581 H HB   . ILE   A 1 105 ? 37.89226 -10.83918 6.57552  1.000 36.19653  ? 102 ILE   A HB   1 
ATOM   1582 H HG12 . ILE   A 1 105 ? 35.21649 -10.14669 5.95445  1.000 36.59121  ? 102 ILE   A HG12 1 
ATOM   1583 H HG13 . ILE   A 1 105 ? 36.41859 -9.92083  4.93988  1.000 36.59121  ? 102 ILE   A HG13 1 
ATOM   1584 H HG21 . ILE   A 1 105 ? 36.20062 -12.02615 7.73792  1.000 34.70550  ? 102 ILE   A HG21 1 
ATOM   1585 H HG22 . ILE   A 1 105 ? 37.20603 -11.24509 8.68797  1.000 34.70550  ? 102 ILE   A HG22 1 
ATOM   1586 H HG23 . ILE   A 1 105 ? 35.76563 -10.64478 8.39069  1.000 34.70550  ? 102 ILE   A HG23 1 
ATOM   1587 H HD11 . ILE   A 1 105 ? 35.32846 -12.38367 5.72390  1.000 42.23679  ? 102 ILE   A HD11 1 
ATOM   1588 H HD12 . ILE   A 1 105 ? 35.42592 -11.81107 4.24534  1.000 42.23679  ? 102 ILE   A HD12 1 
ATOM   1589 H HD13 . ILE   A 1 105 ? 36.73761 -12.30173 4.99515  1.000 42.23679  ? 102 ILE   A HD13 1 
ATOM   1590 N N    . ALA   A 1 106 ? 37.71365 -8.37766  9.52152  1.000 25.78596  ? 103 ALA   A N    1 
ATOM   1591 C CA   . ALA   A 1 106 ? 38.51192 -8.12991  10.71841 1.000 19.00660  ? 103 ALA   A CA   1 
ATOM   1592 C C    . ALA   A 1 106 ? 37.87416 -8.82626  11.90899 1.000 21.74210  ? 103 ALA   A C    1 
ATOM   1593 O O    . ALA   A 1 106 ? 36.66649 -8.69552  12.13491 1.000 24.59934  ? 103 ALA   A O    1 
ATOM   1594 C CB   . ALA   A 1 106 ? 38.64373 -6.63125  10.99262 1.000 21.43182  ? 103 ALA   A CB   1 
ATOM   1595 H H    . ALA   A 1 106 ? 36.87739 -8.20186  9.61832  1.000 30.96181  ? 103 ALA   A H    1 
ATOM   1596 H HA   . ALA   A 1 106 ? 39.39950 -8.50062  10.59320 1.000 22.82657  ? 103 ALA   A HA   1 
ATOM   1597 H HB1  . ALA   A 1 106 ? 39.24497 -6.49904  11.74224 1.000 25.73684  ? 103 ALA   A HB1  1 
ATOM   1598 H HB2  . ALA   A 1 106 ? 38.99961 -6.19571  10.20233 1.000 25.73684  ? 103 ALA   A HB2  1 
ATOM   1599 H HB3  . ALA   A 1 106 ? 37.76825 -6.27054  11.20317 1.000 25.73684  ? 103 ALA   A HB3  1 
ATOM   1600 N N    . ALA   A 1 107 ? 38.68359 -9.56650  12.66262 1.000 20.68015  ? 104 ALA   A N    1 
ATOM   1601 C CA   . ALA   A 1 107 ? 38.19076 -10.31241 13.81072 1.000 19.27095  ? 104 ALA   A CA   1 
ATOM   1602 C C    . ALA   A 1 107 ? 39.24670 -10.33215 14.91041 1.000 20.93325  ? 104 ALA   A C    1 
ATOM   1603 O O    . ALA   A 1 107 ? 40.44402 -10.43081 14.62071 1.000 25.73465  ? 104 ALA   A O    1 
ATOM   1604 C CB   . ALA   A 1 107 ? 37.81981 -11.74281 13.43429 1.000 18.17228  ? 104 ALA   A CB   1 
ATOM   1605 H H    . ALA   A 1 107 ? 39.52842 -9.65191  12.52634 1.000 24.83484  ? 104 ALA   A H    1 
ATOM   1606 H HA   . ALA   A 1 107 ? 37.40307 -9.86351  14.15558 1.000 23.14380  ? 104 ALA   A HA   1 
ATOM   1607 H HB1  . ALA   A 1 107 ? 37.51384 -12.20900 14.22798 1.000 21.82540  ? 104 ALA   A HB1  1 
ATOM   1608 H HB2  . ALA   A 1 107 ? 37.11314 -11.72144 12.77017 1.000 21.82540  ? 104 ALA   A HB2  1 
ATOM   1609 H HB3  . ALA   A 1 107 ? 38.60198 -12.18668 13.07085 1.000 21.82540  ? 104 ALA   A HB3  1 
ATOM   1610 N N    . ILE   A 1 108 ? 38.80234 -10.27196 16.16197 1.000 22.10659  ? 105 ILE   A N    1 
ATOM   1611 C CA   . ILE   A 1 108 ? 39.70453 -10.10259 17.30025 1.000 22.47657  ? 105 ILE   A CA   1 
ATOM   1612 C C    . ILE   A 1 108 ? 39.39961 -11.12455 18.39228 1.000 19.54323  ? 105 ILE   A C    1 
ATOM   1613 O O    . ILE   A 1 108 ? 38.23743 -11.43647 18.67135 1.000 20.24954  ? 105 ILE   A O    1 
ATOM   1614 C CB   . ILE   A 1 108 ? 39.63748 -8.65439  17.84881 1.000 26.19812  ? 105 ILE   A CB   1 
ATOM   1615 C CG1  . ILE   A 1 108 ? 40.60729 -8.47488  19.02057 1.000 23.01912  ? 105 ILE   A CG1  1 
ATOM   1616 C CG2  . ILE   A 1 108 ? 38.21075 -8.28831  18.26337 1.000 24.57385  ? 105 ILE   A CG2  1 
ATOM   1617 C CD1  . ILE   A 1 108 ? 40.98624 -7.03158  19.27211 1.000 19.10600  ? 105 ILE   A CD1  1 
ATOM   1618 H H    . ILE   A 1 108 ? 37.97251 -10.32742 16.38085 1.000 26.54657  ? 105 ILE   A H    1 
ATOM   1619 H HA   . ILE   A 1 108 ? 40.60965 -10.28930 17.00563 1.000 26.99054  ? 105 ILE   A HA   1 
ATOM   1620 H HB   . ILE   A 1 108 ? 39.90585 -8.05404  17.13575 1.000 31.45640  ? 105 ILE   A HB   1 
ATOM   1621 H HG12 . ILE   A 1 108 ? 40.19125 -8.81805  19.82683 1.000 27.64160  ? 105 ILE   A HG12 1 
ATOM   1622 H HG13 . ILE   A 1 108 ? 41.42124 -8.96756  18.83174 1.000 27.64160  ? 105 ILE   A HG13 1 
ATOM   1623 H HG21 . ILE   A 1 108 ? 38.18638 -7.35296  18.51916 1.000 29.50728  ? 105 ILE   A HG21 1 
ATOM   1624 H HG22 . ILE   A 1 108 ? 37.61479 -8.44183  17.51359 1.000 29.50728  ? 105 ILE   A HG22 1 
ATOM   1625 H HG23 . ILE   A 1 108 ? 37.94772 -8.84347  19.01404 1.000 29.50728  ? 105 ILE   A HG23 1 
ATOM   1626 H HD11 . ILE   A 1 108 ? 41.68624 -7.00116  19.94291 1.000 22.94586  ? 105 ILE   A HD11 1 
ATOM   1627 H HD12 . ILE   A 1 108 ? 41.30455 -6.63969  18.44386 1.000 22.94586  ? 105 ILE   A HD12 1 
ATOM   1628 H HD13 . ILE   A 1 108 ? 40.20517 -6.55028  19.58704 1.000 22.94586  ? 105 ILE   A HD13 1 
HETATM 1629 C C    . A1A7V A 1 109 ? 39.90032 -13.89284 19.85721 1.000 24.85604  ? 106 A1A7V A C    1 
HETATM 1630 N N    . A1A7V A 1 109 ? 40.47378 -11.66874 18.98014 1.000 17.81395  ? 106 A1A7V A N    1 
HETATM 1631 O O    . A1A7V A 1 109 ? 40.60438 -14.69799 19.24501 1.000 20.44569  ? 106 A1A7V A O    1 
HETATM 1632 C CA   . A1A7V A 1 109 ? 40.44865 -12.50737 20.17613 1.000 24.01961  ? 106 A1A7V A CA   1 
HETATM 1633 C CB   . A1A7V A 1 109 ? 39.66027 -11.81545 21.29280 1.000 20.98446  ? 106 A1A7V A CB   1 
HETATM 1634 S SG   . A1A7V A 1 109 ? 40.07791 -12.41640 22.94032 1.000 21.48656  ? 106 A1A7V A SG   1 
HETATM 1635 C C1   . A1A7V A 1 109 ? 38.57221 -12.59128 23.85714 0.818 22.52978  ? 106 A1A7V A C1   1 
HETATM 1636 O O1   . A1A7V A 1 109 ? 37.76986 -11.82914 23.41803 0.818 28.69864  ? 106 A1A7V A O1   1 
HETATM 1637 C C2   . A1A7V A 1 109 ? 38.07466 -13.86864 24.47366 0.818 47.18529  ? 106 A1A7V A C2   1 
HETATM 1638 O O2   . A1A7V A 1 109 ? 37.26627 -14.44447 23.48541 0.818 39.94081  ? 106 A1A7V A O2   1 
HETATM 1639 C C3   . A1A7V A 1 109 ? 39.24167 -14.82185 24.78383 0.818 47.52065  ? 106 A1A7V A C3   1 
HETATM 1640 H H    . A1A7V A 1 109 ? 41.27398 -11.55828 18.68507 1.000 21.39540  ? 106 A1A7V A H    1 
HETATM 1641 H HA   . A1A7V A 1 109 ? 41.35205 -12.63571 20.50522 1.000 28.84218  ? 106 A1A7V A HA   1 
HETATM 1642 H HB3  . A1A7V A 1 109 ? 38.71342 -11.97052 21.15022 1.000 25.20001  ? 106 A1A7V A HB3  1 
HETATM 1643 H HB2  . A1A7V A 1 109 ? 39.84838 -10.86424 21.26604 1.000 25.20001  ? 106 A1A7V A HB2  1 
HETATM 1644 H H20  . A1A7V A 1 109 ? 37.53154 -13.68566 25.43008 0.818 56.64101  ? 106 A1A7V A H20  1 
HETATM 1645 H HO2  . A1A7V A 1 109 ? 37.14785 -15.34755 23.75653 0.818 47.94763  ? 106 A1A7V A HO2  1 
HETATM 1646 H H3B  . A1A7V A 1 109 ? 39.65241 -15.30266 23.88988 0.818 57.04343  ? 106 A1A7V A H3B  1 
HETATM 1647 H H3A  . A1A7V A 1 109 ? 38.96109 -15.63940 25.45608 0.818 57.04343  ? 106 A1A7V A H3A  1 
HETATM 1648 H H3   . A1A7V A 1 109 ? 40.08837 -14.32141 25.26516 0.818 57.04343  ? 106 A1A7V A H3   1 
ATOM   1649 N N    . ALA   A 1 110 ? 38.67225 -14.20744 20.28184 1.000 18.90417  ? 107 ALA   A N    1 
ATOM   1650 C CA   . ALA   A 1 110 ? 38.00277 -15.42241 19.81527 1.000 23.47737  ? 107 ALA   A CA   1 
ATOM   1651 C C    . ALA   A 1 110 ? 37.24836 -15.22707 18.50260 1.000 27.69452  ? 107 ALA   A C    1 
ATOM   1652 O O    . ALA   A 1 110 ? 36.83275 -16.21256 17.89311 1.000 21.17454  ? 107 ALA   A O    1 
ATOM   1653 C CB   . ALA   A 1 110 ? 37.01549 -15.92684 20.88090 1.000 23.76554  ? 107 ALA   A CB   1 
ATOM   1654 H H    . ALA   A 1 110 ? 38.21177 -13.73664 20.83493 1.000 22.70365  ? 107 ALA   A H    1 
ATOM   1655 H HA   . ALA   A 1 110 ? 38.67715 -16.10564 19.67626 1.000 28.19150  ? 107 ALA   A HA   1 
ATOM   1656 H HB1  . ALA   A 1 110 ? 36.59151 -16.73804 20.55982 1.000 28.53730  ? 107 ALA   A HB1  1 
ATOM   1657 H HB2  . ALA   A 1 110 ? 37.50140 -16.10959 21.70029 1.000 28.53730  ? 107 ALA   A HB2  1 
ATOM   1658 H HB3  . ALA   A 1 110 ? 36.34532 -15.24366 21.03911 1.000 28.53730  ? 107 ALA   A HB3  1 
ATOM   1659 N N    . GLY   A 1 111 ? 37.06184 -13.97920 18.05532 1.000 22.61270  ? 108 GLY   A N    1 
ATOM   1660 C CA   . GLY   A 1 111 ? 36.33134 -13.72070 16.83170 1.000 25.97029  ? 108 GLY   A CA   1 
ATOM   1661 C C    . GLY   A 1 111 ? 36.79499 -14.50904 15.62743 1.000 25.53488  ? 108 GLY   A C    1 
ATOM   1662 O O    . GLY   A 1 111 ? 35.95859 -14.96724 14.83543 1.000 25.42045  ? 108 GLY   A O    1 
ATOM   1663 H H    . GLY   A 1 111 ? 37.35201 -13.27176 18.44892 1.000 27.15390  ? 108 GLY   A H    1 
ATOM   1664 H HA2  . GLY   A 1 111 ? 35.39607 -13.93136 16.97931 1.000 31.18301  ? 108 GLY   A HA2  1 
ATOM   1665 H HA3  . GLY   A 1 111 ? 36.41260 -12.77849 16.61599 1.000 31.18301  ? 108 GLY   A HA3  1 
ATOM   1666 N N    . PRO   A 1 112 ? 38.10136 -14.69453 15.44816 1.000 18.68719  ? 109 PRO   A N    1 
ATOM   1667 C CA   . PRO   A 1 112 ? 38.58173 -15.41779 14.26272 1.000 22.75738  ? 109 PRO   A CA   1 
ATOM   1668 C C    . PRO   A 1 112 ? 38.09545 -16.84733 14.16525 1.000 20.88627  ? 109 PRO   A C    1 
ATOM   1669 O O    . PRO   A 1 112 ? 38.07823 -17.39741 13.05527 1.000 22.81653  ? 109 PRO   A O    1 
ATOM   1670 C CB   . PRO   A 1 112 ? 40.11238 -15.35315 14.40680 1.000 20.01875  ? 109 PRO   A CB   1 
ATOM   1671 C CG   . PRO   A 1 112 ? 40.34829 -14.12575 15.24508 1.000 23.37154  ? 109 PRO   A CG   1 
ATOM   1672 C CD   . PRO   A 1 112 ? 39.20474 -14.06817 16.19931 1.000 17.83378  ? 109 PRO   A CD   1 
ATOM   1673 H HA   . PRO   A 1 112 ? 38.31184 -14.94203 13.46165 1.000 27.32751  ? 109 PRO   A HA   1 
ATOM   1674 H HB2  . PRO   A 1 112 ? 40.43999 -16.15020 14.85209 1.000 24.04115  ? 109 PRO   A HB2  1 
ATOM   1675 H HB3  . PRO   A 1 112 ? 40.52675 -15.26668 13.53403 1.000 24.04115  ? 109 PRO   A HB3  1 
ATOM   1676 H HG2  . PRO   A 1 112 ? 41.18982 -14.20928 15.72021 1.000 28.06450  ? 109 PRO   A HG2  1 
ATOM   1677 H HG3  . PRO   A 1 112 ? 40.36409 -13.33886 14.67812 1.000 28.06450  ? 109 PRO   A HG3  1 
ATOM   1678 H HD2  . PRO   A 1 112 ? 39.40231 -14.57075 17.00509 1.000 21.41919  ? 109 PRO   A HD2  1 
ATOM   1679 H HD3  . PRO   A 1 112 ? 38.99019 -13.14962 16.42545 1.000 21.41919  ? 109 PRO   A HD3  1 
ATOM   1680 N N    . THR   A 1 113 ? 37.68965 -17.47543 15.27043 1.000 23.25592  ? 110 THR   A N    1 
ATOM   1681 C CA   . THR   A 1 113 ? 37.21957 -18.85149 15.16561 1.000 24.78519  ? 110 THR   A CA   1 
ATOM   1682 C C    . THR   A 1 113 ? 35.93225 -18.93693 14.35792 1.000 26.04143  ? 110 THR   A C    1 
ATOM   1683 O O    . THR   A 1 113 ? 35.59551 -20.01880 13.87614 1.000 25.03131  ? 110 THR   A O    1 
ATOM   1684 C CB   . THR   A 1 113 ? 37.02590 -19.48222 16.54855 1.000 27.77044  ? 110 THR   A CB   1 
ATOM   1685 O OG1  . THR   A 1 113 ? 35.96334 -18.83507 17.25747 1.000 24.30606  ? 110 THR   A OG1  1 
ATOM   1686 C CG2  . THR   A 1 113 ? 38.32396 -19.41163 17.34151 1.000 24.83465  ? 110 THR   A CG2  1 
ATOM   1687 H H    . THR   A 1 113 ? 37.67801 -17.13795 16.06136 1.000 27.92576  ? 110 THR   A H    1 
ATOM   1688 H HA   . THR   A 1 113 ? 37.90089 -19.37845 14.71950 1.000 29.76089  ? 110 THR   A HA   1 
ATOM   1689 H HB   . THR   A 1 113 ? 36.78374 -20.41603 16.44731 1.000 33.34319  ? 110 THR   A HB   1 
ATOM   1690 H HG1  . THR   A 1 113 ? 36.10244 -18.00733 17.29064 1.000 29.18592  ? 110 THR   A HG1  1 
ATOM   1691 H HG21 . THR   A 1 113 ? 38.53578 -18.48821 17.54964 1.000 29.82024  ? 110 THR   A HG21 1 
ATOM   1692 H HG22 . THR   A 1 113 ? 38.23417 -19.90840 18.16979 1.000 29.82024  ? 110 THR   A HG22 1 
ATOM   1693 H HG23 . THR   A 1 113 ? 39.05035 -19.79215 16.82337 1.000 29.82024  ? 110 THR   A HG23 1 
ATOM   1694 N N    . ALA   A 1 114 ? 35.22321 -17.81303 14.18160 1.000 23.73617  ? 111 ALA   A N    1 
ATOM   1695 C CA   . ALA   A 1 114 ? 34.06922 -17.79781 13.28950 1.000 24.24775  ? 111 ALA   A CA   1 
ATOM   1696 C C    . ALA   A 1 114 ? 34.48478 -17.93905 11.82831 1.000 25.73943  ? 111 ALA   A C    1 
ATOM   1697 O O    . ALA   A 1 114 ? 33.70394 -18.43737 11.00771 1.000 29.17561  ? 111 ALA   A O    1 
ATOM   1698 C CB   . ALA   A 1 114 ? 33.26813 -16.50828 13.46912 1.000 26.56314  ? 111 ALA   A CB   1 
ATOM   1699 H H    . ALA   A 1 114 ? 35.39059 -17.06050 14.56277 1.000 28.50206  ? 111 ALA   A H    1 
ATOM   1700 H HA   . ALA   A 1 114 ? 33.49778 -18.54569 13.52409 1.000 29.11595  ? 111 ALA   A HA   1 
ATOM   1701 H HB1  . ALA   A 1 114 ? 32.49966 -16.52891 12.87757 1.000 31.89442  ? 111 ALA   A HB1  1 
ATOM   1702 H HB2  . ALA   A 1 114 ? 32.97408 -16.44503 14.39131 1.000 31.89442  ? 111 ALA   A HB2  1 
ATOM   1703 H HB3  . ALA   A 1 114 ? 33.83417 -15.75171 13.24979 1.000 31.89442  ? 111 ALA   A HB3  1 
ATOM   1704 N N    . LEU   A 1 115 ? 35.67962 -17.46727 11.47450 1.000 21.04637  ? 112 LEU   A N    1 
ATOM   1705 C CA   . LEU   A 1 115 ? 36.15902 -17.65065 10.11205 1.000 18.65134  ? 112 LEU   A CA   1 
ATOM   1706 C C    . LEU   A 1 115 ? 36.33910 -19.12399 9.80981  1.000 26.07594  ? 112 LEU   A C    1 
ATOM   1707 O O    . LEU   A 1 115 ? 36.03997 -19.58325 8.70268  1.000 27.82922  ? 112 LEU   A O    1 
ATOM   1708 C CB   . LEU   A 1 115 ? 37.47961 -16.90476 9.89796  1.000 26.39675  ? 112 LEU   A CB   1 
ATOM   1709 C CG   . LEU   A 1 115 ? 37.43913 -15.42018 10.26530 1.000 27.07820  ? 112 LEU   A CG   1 
ATOM   1710 C CD1  . LEU   A 1 115 ? 38.77562 -14.79184 10.03649 1.000 33.44143  ? 112 LEU   A CD1  1 
ATOM   1711 C CD2  . LEU   A 1 115 ? 36.35829 -14.68554 9.48708  1.000 39.06533  ? 112 LEU   A CD2  1 
ATOM   1712 H H    . LEU   A 1 115 ? 36.21957 -17.04633 11.99495 1.000 25.27430  ? 112 LEU   A H    1 
ATOM   1713 H HA   . LEU   A 1 115 ? 35.50706 -17.27689 9.49873  1.000 22.40026  ? 112 LEU   A HA   1 
ATOM   1714 H HB2  . LEU   A 1 115 ? 38.16212 -17.32374 10.44525 1.000 31.69476  ? 112 LEU   A HB2  1 
ATOM   1715 H HB3  . LEU   A 1 115 ? 37.72072 -16.96841 8.96056  1.000 31.69476  ? 112 LEU   A HB3  1 
ATOM   1716 H HG   . LEU   A 1 115 ? 37.22071 -15.34044 11.20702 1.000 32.51249  ? 112 LEU   A HG   1 
ATOM   1717 H HD11 . LEU   A 1 115 ? 38.74796 -13.87116 10.34061 1.000 40.14837  ? 112 LEU   A HD11 1 
ATOM   1718 H HD12 . LEU   A 1 115 ? 39.44589 -15.28488 10.53503 1.000 40.14837  ? 112 LEU   A HD12 1 
ATOM   1719 H HD13 . LEU   A 1 115 ? 38.98027 -14.82114 9.08877  1.000 40.14837  ? 112 LEU   A HD13 1 
ATOM   1720 H HD21 . LEU   A 1 115 ? 36.43729 -13.73405 9.65833  1.000 46.89705  ? 112 LEU   A HD21 1 
ATOM   1721 H HD22 . LEU   A 1 115 ? 36.47541 -14.86210 8.54050  1.000 46.89705  ? 112 LEU   A HD22 1 
ATOM   1722 H HD23 . LEU   A 1 115 ? 35.48895 -15.00287 9.77767  1.000 46.89705  ? 112 LEU   A HD23 1 
ATOM   1723 N N    . LEU   A 1 116 ? 36.84092 -19.87965 10.78203 1.000 29.17977  ? 113 LEU   A N    1 
ATOM   1724 C CA   . LEU   A 1 116 ? 37.00687 -21.31007 10.56863 1.000 31.81130  ? 113 LEU   A CA   1 
ATOM   1725 C C    . LEU   A 1 116 ? 35.65497 -21.98678 10.40736 1.000 25.88958  ? 113 LEU   A C    1 
ATOM   1726 O O    . LEU   A 1 116 ? 35.47783 -22.82007 9.51680  1.000 29.17178  ? 113 LEU   A O    1 
ATOM   1727 C CB   . LEU   A 1 116 ? 37.79290 -21.92691 11.72170 1.000 23.62140  ? 113 LEU   A CB   1 
ATOM   1728 C CG   . LEU   A 1 116 ? 37.86264 -23.45522 11.73626 1.000 32.13291  ? 113 LEU   A CG   1 
ATOM   1729 C CD1  . LEU   A 1 116 ? 38.63619 -24.00962 10.53852 1.000 26.48580  ? 113 LEU   A CD1  1 
ATOM   1730 C CD2  . LEU   A 1 116 ? 38.50061 -23.91737 13.02974 1.000 28.00214  ? 113 LEU   A CD2  1 
ATOM   1731 H H    . LEU   A 1 116 ? 37.08692 -19.59511 11.55541 1.000 35.03438  ? 113 LEU   A H    1 
ATOM   1732 H HA   . LEU   A 1 116 ? 37.51859 -21.45605 9.75762  1.000 38.19222  ? 113 LEU   A HA   1 
ATOM   1733 H HB2  . LEU   A 1 116 ? 38.70411 -21.59718 11.67833 1.000 28.36433  ? 113 LEU   A HB2  1 
ATOM   1734 H HB3  . LEU   A 1 116 ? 37.37889 -21.64930 12.55382 1.000 28.36433  ? 113 LEU   A HB3  1 
ATOM   1735 H HG   . LEU   A 1 116 ? 36.96015 -23.80514 11.67323 1.000 38.57815  ? 113 LEU   A HG   1 
ATOM   1736 H HD11 . LEU   A 1 116 ? 38.65299 -24.97787 10.59419 1.000 31.80161  ? 113 LEU   A HD11 1 
ATOM   1737 H HD12 . LEU   A 1 116 ? 38.19334 -23.73292 9.72107  1.000 31.80161  ? 113 LEU   A HD12 1 
ATOM   1738 H HD13 . LEU   A 1 116 ? 39.54131 -23.66139 10.55855 1.000 31.80161  ? 113 LEU   A HD13 1 
ATOM   1739 H HD21 . LEU   A 1 116 ? 38.54318 -24.88643 13.03225 1.000 33.62123  ? 113 LEU   A HD21 1 
ATOM   1740 H HD22 . LEU   A 1 116 ? 39.39496 -23.54682 13.09078 1.000 33.62123  ? 113 LEU   A HD22 1 
ATOM   1741 H HD23 . LEU   A 1 116 ? 37.96277 -23.60797 13.77532 1.000 33.62123  ? 113 LEU   A HD23 1 
ATOM   1742 N N    . ALA   A 1 117 ? 34.69014 -21.62725 11.25330 1.000 27.82345  ? 114 ALA   A N    1 
ATOM   1743 C CA   . ALA   A 1 117 ? 33.36992 -22.23085 11.17110 1.000 26.26918  ? 114 ALA   A CA   1 
ATOM   1744 C C    . ALA   A 1 117 ? 32.73835 -22.02084 9.80509  1.000 38.03257  ? 114 ALA   A C    1 
ATOM   1745 O O    . ALA   A 1 117 ? 32.00443 -22.88840 9.32128  1.000 28.34863  ? 114 ALA   A O    1 
ATOM   1746 C CB   . ALA   A 1 117 ? 32.46469 -21.65942 12.26495 1.000 35.07314  ? 114 ALA   A CB   1 
ATOM   1747 H H    . ALA   A 1 117 ? 34.77621 -21.04146 11.87702 1.000 33.40679  ? 114 ALA   A H    1 
ATOM   1748 H HA   . ALA   A 1 117 ? 33.45622 -23.18601 11.31642 1.000 31.54167  ? 114 ALA   A HA   1 
ATOM   1749 H HB1  . ALA   A 1 117 ? 31.58731 -22.06686 12.19358 1.000 42.10642  ? 114 ALA   A HB1  1 
ATOM   1750 H HB2  . ALA   A 1 117 ? 32.85232 -21.85845 13.13157 1.000 42.10642  ? 114 ALA   A HB2  1 
ATOM   1751 H HB3  . ALA   A 1 117 ? 32.39411 -20.69924 12.14680 1.000 42.10642  ? 114 ALA   A HB3  1 
ATOM   1752 N N    . HIS   A 1 118 ? 33.01116 -20.88650 9.16838  1.000 26.35590  ? 115 HIS   A N    1 
ATOM   1753 C CA   . HIS   A 1 118 ? 32.39742 -20.52348 7.90151  1.000 30.43256  ? 115 HIS   A CA   1 
ATOM   1754 C C    . HIS   A 1 118 ? 33.33075 -20.71859 6.72184  1.000 31.03352  ? 115 HIS   A C    1 
ATOM   1755 O O    . HIS   A 1 118 ? 32.99612 -20.29431 5.61771  1.000 29.25375  ? 115 HIS   A O    1 
ATOM   1756 C CB   . HIS   A 1 118 ? 31.91262 -19.07211 7.96811  1.000 31.28206  ? 115 HIS   A CB   1 
ATOM   1757 C CG   . HIS   A 1 118 ? 30.87352 -18.84869 9.02147  1.000 35.45926  ? 115 HIS   A CG   1 
ATOM   1758 N ND1  . HIS   A 1 118 ? 29.78770 -19.68263 9.17636  1.000 29.35947  ? 115 HIS   A ND1  1 
ATOM   1759 C CD2  . HIS   A 1 118 ? 30.76163 -17.90222 9.98406  1.000 34.27576  ? 115 HIS   A CD2  1 
ATOM   1760 C CE1  . HIS   A 1 118 ? 29.05573 -19.26796 10.19430 1.000 26.67116  ? 115 HIS   A CE1  1 
ATOM   1761 N NE2  . HIS   A 1 118 ? 29.61807 -18.18067 10.69427 1.000 24.67502  ? 115 HIS   A NE2  1 
ATOM   1762 H H    . HIS   A 1 118 ? 33.56424 -20.29631 9.46057  1.000 31.64574  ? 115 HIS   A H    1 
ATOM   1763 H HA   . HIS   A 1 118 ? 31.62556 -21.09100 7.74970  1.000 36.53772  ? 115 HIS   A HA   1 
ATOM   1764 H HB2  . HIS   A 1 118 ? 32.66805 -18.49695 8.16662  1.000 37.55712  ? 115 HIS   A HB2  1 
ATOM   1765 H HB3  . HIS   A 1 118 ? 31.52709 -18.82967 7.11167  1.000 37.55712  ? 115 HIS   A HB3  1 
ATOM   1766 H HD2  . HIS   A 1 118 ? 31.34820 -17.19668 10.13591 1.000 41.14957  ? 115 HIS   A HD2  1 
ATOM   1767 H HE1  . HIS   A 1 118 ? 28.27801 -19.67150 10.50608 1.000 32.02404  ? 115 HIS   A HE1  1 
ATOM   1768 H HE2  . HIS   A 1 118 ? 29.31711 -17.72197 11.35655 1.000 29.62868  ? 115 HIS   A HE2  1 
ATOM   1769 N N    . GLU   A 1 119 ? 34.48979 -21.35037 6.93744  1.000 27.87750  ? 116 GLU   A N    1 
ATOM   1770 C CA   . GLU   A 1 119 ? 35.42284 -21.71951 5.87053  1.000 29.61042  ? 116 GLU   A CA   1 
ATOM   1771 C C    . GLU   A 1 119 ? 35.89771 -20.49170 5.10801  1.000 28.08367  ? 116 GLU   A C    1 
ATOM   1772 O O    . GLU   A 1 119 ? 35.93437 -20.47304 3.87663  1.000 27.32977  ? 116 GLU   A O    1 
ATOM   1773 C CB   . GLU   A 1 119 ? 34.79149 -22.74548 4.91911  1.000 37.46267  ? 116 GLU   A CB   1 
ATOM   1774 C CG   . GLU   A 1 119 ? 34.40968 -24.04337 5.61599  1.000 41.33520  ? 116 GLU   A CG   1 
ATOM   1775 C CD   . GLU   A 1 119 ? 34.04186 -25.16882 4.66260  1.000 66.52229  ? 116 GLU   A CD   1 
ATOM   1776 O OE1  . GLU   A 1 119 ? 33.81462 -24.90833 3.45863  1.000 55.53561  ? 116 GLU   A OE1  1 
ATOM   1777 O OE2  . GLU   A 1 119 ? 33.99069 -26.32325 5.13494  1.000 46.75944  ? 116 GLU   A OE2  1 
ATOM   1778 H H    . GLU   A 1 119 ? 34.76541 -21.58262 7.71827  1.000 33.47166  ? 116 GLU   A H    1 
ATOM   1779 H HA   . GLU   A 1 119 ? 36.20287 -22.12828 6.27717  1.000 35.55116  ? 116 GLU   A HA   1 
ATOM   1780 H HB2  . GLU   A 1 119 ? 33.98707 -22.36438 4.53365  1.000 44.97386  ? 116 GLU   A HB2  1 
ATOM   1781 H HB3  . GLU   A 1 119 ? 35.42711 -22.95761 4.21777  1.000 44.97386  ? 116 GLU   A HB3  1 
ATOM   1782 H HG2  . GLU   A 1 119 ? 35.16164 -24.34318 6.15037  1.000 49.62090  ? 116 GLU   A HG2  1 
ATOM   1783 H HG3  . GLU   A 1 119 ? 33.64279 -23.87713 6.18620  1.000 49.62090  ? 116 GLU   A HG3  1 
ATOM   1784 N N    . ILE   A 1 120 ? 36.29336 -19.46709 5.86059  1.000 25.26497  ? 117 ILE   A N    1 
ATOM   1785 C CA   . ILE   A 1 120 ? 36.68510 -18.17728 5.31002  1.000 18.33994  ? 117 ILE   A CA   1 
ATOM   1786 C C    . ILE   A 1 120 ? 38.20290 -18.03471 5.39039  1.000 27.23595  ? 117 ILE   A C    1 
ATOM   1787 O O    . ILE   A 1 120 ? 38.80031 -18.26383 6.44855  1.000 28.30509  ? 117 ILE   A O    1 
ATOM   1788 C CB   . ILE   A 1 120 ? 36.00051 -17.01864 6.06327  1.000 20.95859  ? 117 ILE   A CB   1 
ATOM   1789 C CG1  . ILE   A 1 120 ? 34.47360 -17.14371 6.01755  1.000 31.46086  ? 117 ILE   A CG1  1 
ATOM   1790 C CG2  . ILE   A 1 120 ? 36.46141 -15.69549 5.47048  1.000 29.01905  ? 117 ILE   A CG2  1 
ATOM   1791 C CD1  . ILE   A 1 120 ? 33.87466 -16.96803 4.63765  1.000 31.02791  ? 117 ILE   A CD1  1 
ATOM   1792 H H    . ILE   A 1 120 ? 36.34354 -19.49913 6.71853  1.000 30.33661  ? 117 ILE   A H    1 
ATOM   1793 H HA   . ILE   A 1 120 ? 36.42797 -18.14946 4.37514  1.000 22.02659  ? 117 ILE   A HA   1 
ATOM   1794 H HB   . ILE   A 1 120 ? 36.25807 -17.05954 6.99756  1.000 25.16896  ? 117 ILE   A HB   1 
ATOM   1795 H HG12 . ILE   A 1 120 ? 34.22544 -18.02596 6.33527  1.000 37.77169  ? 117 ILE   A HG12 1 
ATOM   1796 H HG13 . ILE   A 1 120 ? 34.08976 -16.46374 6.59306  1.000 37.77169  ? 117 ILE   A HG13 1 
ATOM   1797 H HG21 . ILE   A 1 120 ? 35.84051 -14.99824 5.73356  1.000 34.84152  ? 117 ILE   A HG21 1 
ATOM   1798 H HG22 . ILE   A 1 120 ? 37.34881 -15.49164 5.80495  1.000 34.84152  ? 117 ILE   A HG22 1 
ATOM   1799 H HG23 . ILE   A 1 120 ? 36.48193 -15.77264 4.50377  1.000 34.84152  ? 117 ILE   A HG23 1 
ATOM   1800 H HD11 . ILE   A 1 120 ? 32.91127 -17.06425 4.69695  1.000 37.25214  ? 117 ILE   A HD11 1 
ATOM   1801 H HD12 . ILE   A 1 120 ? 34.09906 -16.08449 4.30613  1.000 37.25214  ? 117 ILE   A HD12 1 
ATOM   1802 H HD13 . ILE   A 1 120 ? 34.23899 -17.64545 4.04666  1.000 37.25214  ? 117 ILE   A HD13 1 
ATOM   1803 N N    . GLY   A 1 121 ? 38.81632 -17.62977 4.28078  1.000 24.40147  ? 118 GLY   A N    1 
ATOM   1804 C CA   . GLY   A 1 121 ? 40.21768 -17.24815 4.26665  1.000 27.28231  ? 118 GLY   A CA   1 
ATOM   1805 C C    . GLY   A 1 121 ? 41.20842 -18.35761 4.54377  1.000 29.48740  ? 118 GLY   A C    1 
ATOM   1806 O O    . GLY   A 1 121 ? 42.32564 -18.08296 5.01209  1.000 22.05430  ? 118 GLY   A O    1 
ATOM   1807 H H    . GLY   A 1 121 ? 38.43449 -17.56733 3.51272  1.000 29.30042  ? 118 GLY   A H    1 
ATOM   1808 H HA2  . GLY   A 1 121 ? 40.42703 -16.88266 3.39287  1.000 32.75742  ? 118 GLY   A HA2  1 
ATOM   1809 H HA3  . GLY   A 1 121 ? 40.35505 -16.56113 4.93750  1.000 32.75742  ? 118 GLY   A HA3  1 
ATOM   1810 N N    . PHE   A 1 122 ? 40.83856 -19.60662 4.27328  1.000 23.38844  ? 119 PHE   A N    1 
ATOM   1811 C CA   . PHE   A 1 122 ? 41.76870 -20.70701 4.48271  1.000 27.73756  ? 119 PHE   A CA   1 
ATOM   1812 C C    . PHE   A 1 122 ? 43.08278 -20.41678 3.75936  1.000 28.29519  ? 119 PHE   A C    1 
ATOM   1813 O O    . PHE   A 1 122 ? 43.09808 -19.89548 2.63772  1.000 26.45315  ? 119 PHE   A O    1 
ATOM   1814 C CB   . PHE   A 1 122 ? 41.18160 -22.02963 3.98417  1.000 24.24931  ? 119 PHE   A CB   1 
ATOM   1815 C CG   . PHE   A 1 122 ? 40.19345 -22.66773 4.92414  1.000 32.29688  ? 119 PHE   A CG   1 
ATOM   1816 C CD1  . PHE   A 1 122 ? 39.76811 -22.02919 6.08178  1.000 22.66812  ? 119 PHE   A CD1  1 
ATOM   1817 C CD2  . PHE   A 1 122 ? 39.69202 -23.91822 4.64514  1.000 27.29834  ? 119 PHE   A CD2  1 
ATOM   1818 C CE1  . PHE   A 1 122 ? 38.84772 -22.64205 6.92900  1.000 28.33064  ? 119 PHE   A CE1  1 
ATOM   1819 C CE2  . PHE   A 1 122 ? 38.77755 -24.53126 5.48762  1.000 30.16707  ? 119 PHE   A CE2  1 
ATOM   1820 C CZ   . PHE   A 1 122 ? 38.36147 -23.89999 6.62965  1.000 24.60626  ? 119 PHE   A CZ   1 
ATOM   1821 H H    . PHE   A 1 122 ? 40.06688 -19.83821 3.97249  1.000 28.08478  ? 119 PHE   A H    1 
ATOM   1822 H HA   . PHE   A 1 122 ? 41.93727 -20.80414 5.43300  1.000 33.30372  ? 119 PHE   A HA   1 
ATOM   1823 H HB2  . PHE   A 1 122 ? 40.72430 -21.86762 3.14421  1.000 29.11782  ? 119 PHE   A HB2  1 
ATOM   1824 H HB3  . PHE   A 1 122 ? 41.90744 -22.65911 3.85070  1.000 29.11782  ? 119 PHE   A HB3  1 
ATOM   1825 H HD1  . PHE   A 1 122 ? 40.10010 -21.18650 6.29285  1.000 27.22040  ? 119 PHE   A HD1  1 
ATOM   1826 H HD2  . PHE   A 1 122 ? 39.97194 -24.36075 3.87657  1.000 32.77666  ? 119 PHE   A HD2  1 
ATOM   1827 H HE1  . PHE   A 1 122 ? 38.56020 -22.20376 7.69720  1.000 34.01542  ? 119 PHE   A HE1  1 
ATOM   1828 H HE2  . PHE   A 1 122 ? 38.44551 -25.37395 5.27664  1.000 36.21914  ? 119 PHE   A HE2  1 
ATOM   1829 H HZ   . PHE   A 1 122 ? 37.75556 -24.31547 7.19986  1.000 29.54617  ? 119 PHE   A HZ   1 
ATOM   1830 N N    . GLY   A 1 123 ? 44.18715 -20.74849 4.41382  1.000 24.02300  ? 120 GLY   A N    1 
ATOM   1831 C CA   . GLY   A 1 123 ? 45.49979 -20.49377 3.88762  1.000 23.32863  ? 120 GLY   A CA   1 
ATOM   1832 C C    . GLY   A 1 123 ? 46.13045 -19.22180 4.39595  1.000 21.69767  ? 120 GLY   A C    1 
ATOM   1833 O O    . GLY   A 1 123 ? 47.31720 -18.99560 4.13702  1.000 28.84825  ? 120 GLY   A O    1 
ATOM   1834 H H    . GLY   A 1 123 ? 44.19227 -21.13167 5.18372  1.000 28.84626  ? 120 GLY   A H    1 
ATOM   1835 H HA2  . GLY   A 1 123 ? 46.08197 -21.23218 4.12578  1.000 28.01301  ? 120 GLY   A HA2  1 
ATOM   1836 H HA3  . GLY   A 1 123 ? 45.44422 -20.43450 2.92103  1.000 28.01301  ? 120 GLY   A HA3  1 
ATOM   1837 N N    . SER   A 1 124 ? 45.37357 -18.39797 5.11151  1.000 30.09930  ? 121 SER   A N    1 
ATOM   1838 C CA   . SER   A 1 124 ? 45.87559 -17.12026 5.57581  1.000 25.54490  ? 121 SER   A CA   1 
ATOM   1839 C C    . SER   A 1 124 ? 46.63702 -17.28294 6.88234  1.000 27.93880  ? 121 SER   A C    1 
ATOM   1840 O O    . SER   A 1 124 ? 46.42704 -18.22843 7.65011  1.000 23.30545  ? 121 SER   A O    1 
ATOM   1841 C CB   . SER   A 1 124 ? 44.73366 -16.12184 5.79243  1.000 31.36968  ? 121 SER   A CB   1 
ATOM   1842 O OG   . SER   A 1 124 ? 43.96849 -15.90662 4.62391  1.000 32.31914  ? 121 SER   A OG   1 
ATOM   1843 H H    . SER   A 1 124 ? 44.56081 -18.56025 5.34102  1.000 36.13781  ? 121 SER   A H    1 
ATOM   1844 H HA   . SER   A 1 124 ? 46.47405 -16.76412 4.90061  1.000 30.67253  ? 121 SER   A HA   1 
ATOM   1845 H HB2  . SER   A 1 124 ? 44.14876 -16.46783 6.48459  1.000 37.66227  ? 121 SER   A HB2  1 
ATOM   1846 H HB3  . SER   A 1 124 ? 45.11391 -15.27452 6.07237  1.000 37.66227  ? 121 SER   A HB3  1 
ATOM   1847 H HG   . SER   A 1 124 ? 43.65672 -16.63557 4.34634  1.000 38.80163  ? 121 SER   A HG   1 
ATOM   1848 N N    . LYS   A 1 125 ? 47.52913 -16.33766 7.12836  1.000 22.17538  ? 122 LYS   A N    1 
ATOM   1849 C CA   . LYS   A 1 125 ? 48.15528 -16.21217 8.43512  1.000 23.91587  ? 122 LYS   A CA   1 
ATOM   1850 C C    . LYS   A 1 125 ? 47.21597 -15.42298 9.33954  1.000 24.31023  ? 122 LYS   A C    1 
ATOM   1851 O O    . LYS   A 1 125 ? 46.72031 -14.36051 8.95270  1.000 22.89091  ? 122 LYS   A O    1 
ATOM   1852 C CB   . LYS   A 1 125 ? 49.50515 -15.51678 8.31690  1.000 22.80592  ? 122 LYS   A CB   1 
ATOM   1853 C CG   . LYS   A 1 125 ? 50.28910 -15.48526 9.61779  1.000 50.86619  ? 122 LYS   A CG   1 
ATOM   1854 C CD   . LYS   A 1 125 ? 51.66929 -14.85846 9.44681  1.000 57.30347  ? 122 LYS   A CD   1 
ATOM   1855 C CE   . LYS   A 1 125 ? 52.58414 -15.73306 8.61045  1.000 58.70844  ? 122 LYS   A CE   1 
ATOM   1856 N NZ   . LYS   A 1 125 ? 53.95349 -15.14921 8.51084  1.000 70.06233  ? 122 LYS   A NZ   1 
ATOM   1857 H H    . LYS   A 1 125 ? 47.79083 -15.75361 6.55391  1.000 26.62911  ? 122 LYS   A H    1 
ATOM   1858 H HA   . LYS   A 1 125 ? 48.31682 -17.08612 8.82372  1.000 28.71770  ? 122 LYS   A HA   1 
ATOM   1859 H HB2  . LYS   A 1 125 ? 50.04144 -15.98554 7.65846  1.000 27.38575  ? 122 LYS   A HB2  1 
ATOM   1860 H HB3  . LYS   A 1 125 ? 49.36062 -14.59991 8.03518  1.000 27.38575  ? 122 LYS   A HB3  1 
ATOM   1861 H HG2  . LYS   A 1 125 ? 49.79948 -14.96240 10.27184 1.000 61.05809  ? 122 LYS   A HG2  1 
ATOM   1862 H HG3  . LYS   A 1 125 ? 50.40781 -16.39248 9.93989  1.000 61.05809  ? 122 LYS   A HG3  1 
ATOM   1863 H HD2  . LYS   A 1 125 ? 51.57890 -14.00103 9.00236  1.000 68.78281  ? 122 LYS   A HD2  1 
ATOM   1864 H HD3  . LYS   A 1 125 ? 52.07705 -14.73882 10.31877 1.000 68.78281  ? 122 LYS   A HD3  1 
ATOM   1865 H HE2  . LYS   A 1 125 ? 52.65469 -16.60923 9.02062  1.000 70.46879  ? 122 LYS   A HE2  1 
ATOM   1866 H HE3  . LYS   A 1 125 ? 52.22079 -15.81433 7.71475  1.000 70.46879  ? 122 LYS   A HE3  1 
ATOM   1867 H HZ1  . LYS   A 1 125 ? 53.90676 -14.31323 8.20909  1.000 84.09345  ? 122 LYS   A HZ1  1 
ATOM   1868 H HZ2  . LYS   A 1 125 ? 54.34200 -15.14596 9.31156  1.000 84.09345  ? 122 LYS   A HZ2  1 
ATOM   1869 H HZ3  . LYS   A 1 125 ? 54.44987 -15.63107 7.95092  1.000 84.09345  ? 122 LYS   A HZ3  1 
ATOM   1870 N N    . VAL   A 1 126 ? 46.96056 -15.95703 10.53608 1.000 25.43029  ? 123 VAL   A N    1 
ATOM   1871 C CA   . VAL   A 1 126 ? 46.01918 -15.36859 11.47763 1.000 24.04872  ? 123 VAL   A CA   1 
ATOM   1872 C C    . VAL   A 1 126 ? 46.58512 -15.43297 12.88795 1.000 22.70270  ? 123 VAL   A C    1 
ATOM   1873 O O    . VAL   A 1 126 ? 47.43184 -16.27216 13.20978 1.000 23.92158  ? 123 VAL   A O    1 
ATOM   1874 C CB   . VAL   A 1 126 ? 44.65053 -16.08796 11.45202 1.000 21.75189  ? 123 VAL   A CB   1 
ATOM   1875 C CG1  . VAL   A 1 126 ? 44.04508 -16.05002 10.07335 1.000 25.73375  ? 123 VAL   A CG1  1 
ATOM   1876 C CG2  . VAL   A 1 126 ? 44.78842 -17.54021 11.93727 1.000 24.07687  ? 123 VAL   A CG2  1 
ATOM   1877 H H    . VAL   A 1 126 ? 47.33105 -16.67643 10.82729 1.000 30.53500  ? 123 VAL   A H    1 
ATOM   1878 H HA   . VAL   A 1 126 ? 45.90121 -14.43496 11.24246 1.000 28.87712  ? 123 VAL   A HA   1 
ATOM   1879 H HB   . VAL   A 1 126 ? 44.05147 -15.62112 12.05541 1.000 26.12093  ? 123 VAL   A HB   1 
ATOM   1880 H HG11 . VAL   A 1 126 ? 43.14484 -16.40896 10.11380 1.000 30.89915  ? 123 VAL   A HG11 1 
ATOM   1881 H HG12 . VAL   A 1 126 ? 44.02114 -15.13093 9.76414  1.000 30.89915  ? 123 VAL   A HG12 1 
ATOM   1882 H HG13 . VAL   A 1 126 ? 44.58843 -16.58629 9.47496  1.000 30.89915  ? 123 VAL   A HG13 1 
ATOM   1883 H HG21 . VAL   A 1 126 ? 44.00349 -18.04034 11.66405 1.000 28.91089  ? 123 VAL   A HG21 1 
ATOM   1884 H HG22 . VAL   A 1 126 ? 45.58360 -17.93095 11.54241 1.000 28.91089  ? 123 VAL   A HG22 1 
ATOM   1885 H HG23 . VAL   A 1 126 ? 44.86315 -17.54428 12.90438 1.000 28.91089  ? 123 VAL   A HG23 1 
ATOM   1886 N N    . THR   A 1 127 ? 46.06653 -14.55967 13.74918 1.000 26.26021  ? 124 THR   A N    1 
ATOM   1887 C CA   . THR   A 1 127 ? 46.29649 -14.66401 15.18225 1.000 17.32185  ? 124 THR   A CA   1 
ATOM   1888 C C    . THR   A 1 127 ? 44.95643 -14.69429 15.91328 1.000 18.35087  ? 124 THR   A C    1 
ATOM   1889 O O    . THR   A 1 127 ? 43.90946 -14.35740 15.35476 1.000 22.69103  ? 124 THR   A O    1 
ATOM   1890 C CB   . THR   A 1 127 ? 47.16256 -13.51433 15.72459 1.000 20.08288  ? 124 THR   A CB   1 
ATOM   1891 O OG1  . THR   A 1 127 ? 47.63123 -13.86274 17.03879 1.000 20.00918  ? 124 THR   A OG1  1 
ATOM   1892 C CG2  . THR   A 1 127 ? 46.35997 -12.20114 15.77742 1.000 23.48221  ? 124 THR   A CG2  1 
ATOM   1893 H H    . THR   A 1 127 ? 45.57359 -13.89259 13.52200 1.000 31.53091  ? 124 THR   A H    1 
ATOM   1894 H HA   . THR   A 1 127 ? 46.76524 -15.49402 15.36186 1.000 20.80487  ? 124 THR   A HA   1 
ATOM   1895 H HB   . THR   A 1 127 ? 47.92189 -13.36651 15.13937 1.000 24.11811  ? 124 THR   A HB   1 
ATOM   1896 H HG1  . THR   A 1 127 ? 48.00274 -14.61591 17.02101 1.000 24.02967  ? 124 THR   A HG1  1 
ATOM   1897 H HG21 . THR   A 1 127 ? 46.96387 -11.44619 15.85652 1.000 28.19731  ? 124 THR   A HG21 1 
ATOM   1898 H HG22 . THR   A 1 127 ? 45.83464 -12.10061 14.96821 1.000 28.19731  ? 124 THR   A HG22 1 
ATOM   1899 H HG23 . THR   A 1 127 ? 45.76268 -12.20790 16.54168 1.000 28.19731  ? 124 THR   A HG23 1 
ATOM   1900 N N    . THR   A 1 128 ? 45.01308 -15.15815 17.16049 1.000 19.30400  ? 125 THR   A N    1 
ATOM   1901 C CA   . THR   A 1 128 ? 43.85103 -15.25637 18.02067 1.000 22.55738  ? 125 THR   A CA   1 
ATOM   1902 C C    . THR   A 1 128 ? 44.30878 -14.98345 19.44691 1.000 21.96758  ? 125 THR   A C    1 
ATOM   1903 O O    . THR   A 1 128 ? 45.50218 -14.82577 19.71487 1.000 21.71081  ? 125 THR   A O    1 
ATOM   1904 C CB   . THR   A 1 128 ? 43.20356 -16.64417 17.97751 1.000 22.95350  ? 125 THR   A CB   1 
ATOM   1905 O OG1  . THR   A 1 128 ? 44.06492 -17.57722 18.64863 1.000 19.48770  ? 125 THR   A OG1  1 
ATOM   1906 C CG2  . THR   A 1 128 ? 42.96488 -17.11646 16.55738 1.000 25.53582  ? 125 THR   A CG2  1 
ATOM   1907 H H    . THR   A 1 128 ? 45.73747 -15.42869 17.53688 1.000 23.18346  ? 125 THR   A H    1 
ATOM   1908 H HA   . THR   A 1 128 ? 43.20709 -14.59649 17.71932 1.000 27.08751  ? 125 THR   A HA   1 
ATOM   1909 H HB   . THR   A 1 128 ? 42.33847 -16.60282 18.41435 1.000 27.56285  ? 125 THR   A HB   1 
ATOM   1910 H HG1  . THR   A 1 128 ? 43.99089 -17.48930 19.48073 1.000 23.40390  ? 125 THR   A HG1  1 
ATOM   1911 H HG21 . THR   A 1 128 ? 42.47284 -17.95238 16.56404 1.000 30.66164  ? 125 THR   A HG21 1 
ATOM   1912 H HG22 . THR   A 1 128 ? 42.45237 -16.45338 16.06895 1.000 30.66164  ? 125 THR   A HG22 1 
ATOM   1913 H HG23 . THR   A 1 128 ? 43.81268 -17.25379 16.10652 1.000 30.66164  ? 125 THR   A HG23 1 
ATOM   1914 N N    . HIS   A 1 129 ? 43.36073 -14.98032 20.37435 1.000 22.31725  ? 126 HIS   A N    1 
ATOM   1915 C CA   . HIS   A 1 129 ? 43.75832 -15.05780 21.77238 1.000 21.96166  ? 126 HIS   A CA   1 
ATOM   1916 C C    . HIS   A 1 129 ? 44.49942 -16.37693 21.99487 1.000 19.52785  ? 126 HIS   A C    1 
ATOM   1917 O O    . HIS   A 1 129 ? 44.15115 -17.39414 21.37753 1.000 21.85936  ? 126 HIS   A O    1 
ATOM   1918 C CB   . HIS   A 1 129 ? 42.54813 -14.96781 22.70185 1.000 18.30762  ? 126 HIS   A CB   1 
ATOM   1919 C CG   . HIS   A 1 129 ? 42.91199 -14.72228 24.13467 1.000 17.24962  ? 126 HIS   A CG   1 
ATOM   1920 N ND1  . HIS   A 1 129 ? 43.22429 -15.74062 25.00650 1.000 22.04925  ? 126 HIS   A ND1  1 
ATOM   1921 C CD2  . HIS   A 1 129 ? 43.04254 -13.57540 24.83876 1.000 25.11271  ? 126 HIS   A CD2  1 
ATOM   1922 C CE1  . HIS   A 1 129 ? 43.53256 -15.23521 26.18633 1.000 26.37492  ? 126 HIS   A CE1  1 
ATOM   1923 N NE2  . HIS   A 1 129 ? 43.42020 -13.92134 26.11595 1.000 20.63476  ? 126 HIS   A NE2  1 
ATOM   1924 H H    . HIS   A 1 129 ? 42.51454 -14.93598 20.22742 1.000 26.79935  ? 126 HIS   A H    1 
ATOM   1925 H HA   . HIS   A 1 129 ? 44.34193 -14.31481 21.99207 1.000 26.37264  ? 126 HIS   A HA   1 
ATOM   1926 H HB2  . HIS   A 1 129 ? 41.98267 -14.23599 22.40928 1.000 21.98780  ? 126 HIS   A HB2  1 
ATOM   1927 H HB3  . HIS   A 1 129 ? 42.05776 -15.80363 22.65884 1.000 21.98780  ? 126 HIS   A HB3  1 
ATOM   1928 H HD2  . HIS   A 1 129 ? 42.90305 -12.71319 24.51932 1.000 30.15391  ? 126 HIS   A HD2  1 
ATOM   1929 H HE1  . HIS   A 1 129 ? 43.78543 -15.72098 26.93799 1.000 31.66856  ? 126 HIS   A HE1  1 
ATOM   1930 H HE2  . HIS   A 1 129 ? 43.56015 -13.37182 26.76252 1.000 24.78037  ? 126 HIS   A HE2  1 
ATOM   1931 N N    . PRO   A 1 130 ? 45.52532 -16.39897 22.84844 1.000 21.43264  ? 127 PRO   A N    1 
ATOM   1932 C CA   . PRO   A 1 130 ? 46.23555 -17.66484 23.11090 1.000 26.47464  ? 127 PRO   A CA   1 
ATOM   1933 C C    . PRO   A 1 130 ? 45.32002 -18.80128 23.48527 1.000 23.25317  ? 127 PRO   A C    1 
ATOM   1934 O O    . PRO   A 1 130 ? 45.57534 -19.95188 23.10052 1.000 27.11656  ? 127 PRO   A O    1 
ATOM   1935 C CB   . PRO   A 1 130 ? 47.18598 -17.30308 24.25810 1.000 29.22367  ? 127 PRO   A CB   1 
ATOM   1936 C CG   . PRO   A 1 130 ? 47.41959 -15.84400 24.09284 1.000 28.44746  ? 127 PRO   A CG   1 
ATOM   1937 C CD   . PRO   A 1 130 ? 46.13066 -15.26074 23.55853 1.000 23.41089  ? 127 PRO   A CD   1 
ATOM   1938 H HA   . PRO   A 1 130 ? 46.75713 -17.91613 22.33262 1.000 31.78822  ? 127 PRO   A HA   1 
ATOM   1939 H HB2  . PRO   A 1 130 ? 46.76697 -17.49595 25.11141 1.000 35.08706  ? 127 PRO   A HB2  1 
ATOM   1940 H HB3  . PRO   A 1 130 ? 48.01385 -17.80166 24.17480 1.000 35.08706  ? 127 PRO   A HB3  1 
ATOM   1941 H HG2  . PRO   A 1 130 ? 47.64149 -15.45152 24.95168 1.000 34.15560  ? 127 PRO   A HG2  1 
ATOM   1942 H HG3  . PRO   A 1 130 ? 48.14505 -15.70052 23.46513 1.000 34.15560  ? 127 PRO   A HG3  1 
ATOM   1943 H HD2  . PRO   A 1 130 ? 45.55951 -14.96025 24.28267 1.000 28.11172  ? 127 PRO   A HD2  1 
ATOM   1944 H HD3  . PRO   A 1 130 ? 46.30823 -14.52683 22.94964 1.000 28.11172  ? 127 PRO   A HD3  1 
ATOM   1945 N N    . LEU   A 1 131 ? 44.23635 -18.51671 24.20046 1.000 20.18187  ? 128 LEU   A N    1 
ATOM   1946 C CA   . LEU   A 1 131 ? 43.31474 -19.56633 24.61554 1.000 21.47566  ? 128 LEU   A CA   1 
ATOM   1947 C C    . LEU   A 1 131 ? 42.45369 -20.07723 23.47849 1.000 28.18751  ? 128 LEU   A C    1 
ATOM   1948 O O    . LEU   A 1 131 ? 41.84746 -21.13817 23.61808 1.000 27.62245  ? 128 LEU   A O    1 
ATOM   1949 C CB   . LEU   A 1 131 ? 42.41108 -19.05416 25.73620 1.000 22.51634  ? 128 LEU   A CB   1 
ATOM   1950 C CG   . LEU   A 1 131 ? 43.09147 -18.76605 27.07306 1.000 30.70997  ? 128 LEU   A CG   1 
ATOM   1951 C CD1  . LEU   A 1 131 ? 42.09953 -18.16537 28.05493 1.000 32.15029  ? 128 LEU   A CD1  1 
ATOM   1952 C CD2  . LEU   A 1 131 ? 43.69752 -20.03883 27.63485 1.000 42.45734  ? 128 LEU   A CD2  1 
ATOM   1953 H H    . LEU   A 1 131 ? 44.01346 -17.72668 24.45695 1.000 24.23689  ? 128 LEU   A H    1 
ATOM   1954 H HA   . LEU   A 1 131 ? 43.83468 -20.31052 24.95720 1.000 25.78945  ? 128 LEU   A HA   1 
ATOM   1955 H HB2  . LEU   A 1 131 ? 42.00176 -18.22648 25.43904 1.000 27.03827  ? 128 LEU   A HB2  1 
ATOM   1956 H HB3  . LEU   A 1 131 ? 41.72717 -19.72198 25.90110 1.000 27.03827  ? 128 LEU   A HB3  1 
ATOM   1957 H HG   . LEU   A 1 131 ? 43.80510 -18.12291 26.93887 1.000 36.87062  ? 128 LEU   A HG   1 
ATOM   1958 H HD11 . LEU   A 1 131 ? 42.54283 -18.02634 28.90643 1.000 38.59900  ? 128 LEU   A HD11 1 
ATOM   1959 H HD12 . LEU   A 1 131 ? 41.78236 -17.31814 27.70491 1.000 38.59900  ? 128 LEU   A HD12 1 
ATOM   1960 H HD13 . LEU   A 1 131 ? 41.35493 -18.77710 28.16565 1.000 38.59900  ? 128 LEU   A HD13 1 
ATOM   1961 H HD21 . LEU   A 1 131 ? 43.95443 -19.88574 28.55760 1.000 50.96746  ? 128 LEU   A HD21 1 
ATOM   1962 H HD22 . LEU   A 1 131 ? 43.03893 -20.74946 27.58840 1.000 50.96746  ? 128 LEU   A HD22 1 
ATOM   1963 H HD23 . LEU   A 1 131 ? 44.47758 -20.27591 27.10929 1.000 50.96746  ? 128 LEU   A HD23 1 
ATOM   1964 N N    . ALA   A 1 132 ? 42.39142 -19.36796 22.36388 1.000 23.53590  ? 129 ALA   A N    1 
ATOM   1965 C CA   . ALA   A 1 132 ? 41.61044 -19.80263 21.21072 1.000 20.43537  ? 129 ALA   A CA   1 
ATOM   1966 C C    . ALA   A 1 132 ? 42.45775 -20.42645 20.10365 1.000 20.76214  ? 129 ALA   A C    1 
ATOM   1967 O O    . ALA   A 1 132 ? 41.91011 -20.82524 19.07065 1.000 24.91146  ? 129 ALA   A O    1 
ATOM   1968 C CB   . ALA   A 1 132 ? 40.82183 -18.61162 20.66099 1.000 20.62974  ? 129 ALA   A CB   1 
ATOM   1969 H H    . ALA   A 1 132 ? 42.79799 -18.61933 22.24615 1.000 28.26173  ? 129 ALA   A H    1 
ATOM   1970 H HA   . ALA   A 1 132 ? 40.97995 -20.48261 21.49534 1.000 24.54110  ? 129 ALA   A HA   1 
ATOM   1971 H HB1  . ALA   A 1 132 ? 40.28405 -18.90838 19.91024 1.000 24.77434  ? 129 ALA   A HB1  1 
ATOM   1972 H HB2  . ALA   A 1 132 ? 40.24840 -18.26235 21.36106 1.000 24.77434  ? 129 ALA   A HB2  1 
ATOM   1973 H HB3  . ALA   A 1 132 ? 41.44488 -17.92690 20.37141 1.000 24.77434  ? 129 ALA   A HB3  1 
ATOM   1974 N N    . LYS   A 1 133 ? 43.76952 -20.53710 20.30182 1.000 19.64936  ? 130 LYS   A N    1 
ATOM   1975 C CA   . LYS   A 1 133 ? 44.65042 -21.03782 19.25284 1.000 25.46402  ? 130 LYS   A CA   1 
ATOM   1976 C C    . LYS   A 1 133 ? 44.26162 -22.44614 18.81648 1.000 30.41457  ? 130 LYS   A C    1 
ATOM   1977 O O    . LYS   A 1 133 ? 44.11297 -22.71627 17.61623 1.000 21.25046  ? 130 LYS   A O    1 
ATOM   1978 C CB   . LYS   A 1 133 ? 46.09582 -21.01788 19.73252 1.000 28.28945  ? 130 LYS   A CB   1 
ATOM   1979 C CG   . LYS   A 1 133 ? 47.07480 -21.69874 18.76805 1.000 28.06646  ? 130 LYS   A CG   1 
ATOM   1980 C CD   . LYS   A 1 133 ? 48.48996 -21.63081 19.29278 1.000 27.44889  ? 130 LYS   A CD   1 
ATOM   1981 C CE   . LYS   A 1 133 ? 49.47336 -22.23138 18.31577 1.000 37.56571  ? 130 LYS   A CE   1 
ATOM   1982 N NZ   . LYS   A 1 133 ? 50.10152 -23.43751 18.88744 1.000 39.24661  ? 130 LYS   A NZ   1 
ATOM   1983 H H    . LYS   A 1 133 ? 44.17310 -20.32961 21.03235 1.000 23.59789  ? 130 LYS   A H    1 
ATOM   1984 H HA   . LYS   A 1 133 ? 44.57020 -20.45185 18.48401 1.000 30.57548  ? 130 LYS   A HA   1 
ATOM   1985 H HB2  . LYS   A 1 133 ? 46.37688 -20.09550 19.83799 1.000 33.96599  ? 130 LYS   A HB2  1 
ATOM   1986 H HB3  . LYS   A 1 133 ? 46.14851 -21.48014 20.58366 1.000 33.96599  ? 130 LYS   A HB3  1 
ATOM   1987 H HG2  . LYS   A 1 133 ? 46.83038 -22.63178 18.66509 1.000 33.69840  ? 130 LYS   A HG2  1 
ATOM   1988 H HG3  . LYS   A 1 133 ? 47.04481 -21.25108 17.90805 1.000 33.69840  ? 130 LYS   A HG3  1 
ATOM   1989 H HD2  . LYS   A 1 133 ? 48.73392 -20.70351 19.43942 1.000 32.95732  ? 130 LYS   A HD2  1 
ATOM   1990 H HD3  . LYS   A 1 133 ? 48.54770 -22.12473 20.12561 1.000 32.95732  ? 130 LYS   A HD3  1 
ATOM   1991 H HE2  . LYS   A 1 133 ? 49.01004 -22.48108 17.50098 1.000 45.09750  ? 130 LYS   A HE2  1 
ATOM   1992 H HE3  . LYS   A 1 133 ? 50.16916 -21.58540 18.11710 1.000 45.09750  ? 130 LYS   A HE3  1 
ATOM   1993 H HZ1  . LYS   A 1 133 ? 50.68912 -23.77677 18.31148 1.000 47.11459  ? 130 LYS   A HZ1  1 
ATOM   1994 H HZ2  . LYS   A 1 133 ? 50.52383 -23.23161 19.64332 1.000 47.11459  ? 130 LYS   A HZ2  1 
ATOM   1995 H HZ3  . LYS   A 1 133 ? 49.48046 -24.05080 19.06140 1.000 47.11459  ? 130 LYS   A HZ3  1 
ATOM   1996 N N    . ASP   A 1 134 ? 44.11538 -23.36534 19.77337 1.000 24.79696  ? 131 ASP   A N    1 
ATOM   1997 C CA   . ASP   A 1 134 ? 43.83030 -24.75132 19.41782 1.000 23.84138  ? 131 ASP   A CA   1 
ATOM   1998 C C    . ASP   A 1 134 ? 42.57156 -24.85484 18.57221 1.000 29.59491  ? 131 ASP   A C    1 
ATOM   1999 O O    . ASP   A 1 134 ? 42.52582 -25.61921 17.59812 1.000 28.98758  ? 131 ASP   A O    1 
ATOM   2000 C CB   . ASP   A 1 134 ? 43.68506 -25.60944 20.67766 1.000 36.52891  ? 131 ASP   A CB   1 
ATOM   2001 C CG   . ASP   A 1 134 ? 45.00616 -25.80874 21.40626 1.000 40.72102  ? 131 ASP   A CG   1 
ATOM   2002 O OD1  . ASP   A 1 134 ? 46.06631 -25.64811 20.76514 1.000 36.77194  ? 131 ASP   A OD1  1 
ATOM   2003 O OD2  . ASP   A 1 134 ? 44.98133 -26.12619 22.61453 1.000 58.59006  ? 131 ASP   A OD2  1 
ATOM   2004 H H    . ASP   A 1 134 ? 44.17545 -23.21395 20.61780 1.000 29.77501  ? 131 ASP   A H    1 
ATOM   2005 H HA   . ASP   A 1 134 ? 44.57817 -25.09329 18.90338 1.000 28.62831  ? 131 ASP   A HA   1 
ATOM   2006 H HB2  . ASP   A 1 134 ? 43.06833 -25.17485 21.28731 1.000 43.85335  ? 131 ASP   A HB2  1 
ATOM   2007 H HB3  . ASP   A 1 134 ? 43.34479 -26.48289 20.42823 1.000 43.85335  ? 131 ASP   A HB3  1 
ATOM   2008 N N    . LYS   A 1 135 ? 41.53477 -24.09807 18.93253 1.000 25.52843  ? 132 LYS   A N    1 
ATOM   2009 C CA   . LYS   A 1 135 ? 40.28312 -24.15628 18.19224 1.000 25.04256  ? 132 LYS   A CA   1 
ATOM   2010 C C    . LYS   A 1 135 ? 40.47055 -23.64317 16.77326 1.000 23.53883  ? 132 LYS   A C    1 
ATOM   2011 O O    . LYS   A 1 135 ? 39.98804 -24.26137 15.81211 1.000 22.44300  ? 132 LYS   A O    1 
ATOM   2012 C CB   . LYS   A 1 135 ? 39.20730 -23.34910 18.93228 1.000 33.67928  ? 132 LYS   A CB   1 
ATOM   2013 C CG   . LYS   A 1 135 ? 37.86669 -23.26294 18.21429 1.000 57.72852  ? 132 LYS   A CG   1 
ATOM   2014 C CD   . LYS   A 1 135 ? 36.75969 -23.99906 18.96070 1.000 97.11842  ? 132 LYS   A CD   1 
ATOM   2015 C CE   . LYS   A 1 135 ? 35.45681 -23.96306 18.16963 1.000 104.24233 ? 132 LYS   A CE   1 
ATOM   2016 N NZ   . LYS   A 1 135 ? 34.28356 -24.31357 19.00724 1.000 90.11677  ? 132 LYS   A NZ   1 
ATOM   2017 H H    . LYS   A 1 135 ? 41.53273 -23.54952 19.59486 1.000 30.65277  ? 132 LYS   A H    1 
ATOM   2018 H HA   . LYS   A 1 135 ? 39.98045 -25.07631 18.13910 1.000 30.06972  ? 132 LYS   A HA   1 
ATOM   2019 H HB2  . LYS   A 1 135 ? 39.05012 -23.76406 19.79484 1.000 40.43380  ? 132 LYS   A HB2  1 
ATOM   2020 H HB3  . LYS   A 1 135 ? 39.53171 -22.44312 19.05416 1.000 40.43380  ? 132 LYS   A HB3  1 
ATOM   2021 H HG2  . LYS   A 1 135 ? 37.60811 -22.33145 18.13448 1.000 69.29288  ? 132 LYS   A HG2  1 
ATOM   2022 H HG3  . LYS   A 1 135 ? 37.95169 -23.66029 17.33350 1.000 69.29288  ? 132 LYS   A HG3  1 
ATOM   2023 H HD2  . LYS   A 1 135 ? 37.01628 -24.92564 19.08919 1.000 116.56076 ? 132 LYS   A HD2  1 
ATOM   2024 H HD3  . LYS   A 1 135 ? 36.61008 -23.57407 19.81971 1.000 116.56076 ? 132 LYS   A HD3  1 
ATOM   2025 H HE2  . LYS   A 1 135 ? 35.32155 -23.06879 17.81909 1.000 125.10945 ? 132 LYS   A HE2  1 
ATOM   2026 H HE3  . LYS   A 1 135 ? 35.50902 -24.60079 17.44061 1.000 125.10945 ? 132 LYS   A HE3  1 
ATOM   2027 H HZ1  . LYS   A 1 135 ? 33.54427 -24.31148 18.51172 1.000 108.15878 ? 132 LYS   A HZ1  1 
ATOM   2028 H HZ2  . LYS   A 1 135 ? 34.39248 -25.12333 19.36010 1.000 108.15878 ? 132 LYS   A HZ2  1 
ATOM   2029 H HZ3  . LYS   A 1 135 ? 34.19175 -23.72163 19.66548 1.000 108.15878 ? 132 LYS   A HZ3  1 
ATOM   2030 N N    . MET   A 1 136 ? 41.17207 -22.51846 16.62438 1.000 23.26723  ? 133 MET   A N    1 
ATOM   2031 C CA   . MET   A 1 136 ? 41.40120 -21.94588 15.30482 1.000 30.05525  ? 133 MET   A CA   1 
ATOM   2032 C C    . MET   A 1 136 ? 42.21117 -22.87830 14.41149 1.000 27.63665  ? 133 MET   A C    1 
ATOM   2033 O O    . MET   A 1 136 ? 42.03403 -22.88595 13.18738 1.000 24.24261  ? 133 MET   A O    1 
ATOM   2034 C CB   . MET   A 1 136 ? 42.12975 -20.61047 15.46864 1.000 22.13352  ? 133 MET   A CB   1 
ATOM   2035 C CG   . MET   A 1 136 ? 42.30150 -19.81578 14.19441 1.000 20.80689  ? 133 MET   A CG   1 
ATOM   2036 S SD   . MET   A 1 136 ? 40.70971 -19.16651 13.70482 1.000 23.82769  ? 133 MET   A SD   1 
ATOM   2037 C CE   . MET   A 1 136 ? 41.07920 -18.35091 12.17421 1.000 26.91495  ? 133 MET   A CE   1 
ATOM   2038 H H    . MET   A 1 136 ? 41.52345 -22.07133 17.26951 1.000 27.93933  ? 133 MET   A H    1 
ATOM   2039 H HA   . MET   A 1 136 ? 40.54554 -21.78783 14.87613 1.000 36.08495  ? 133 MET   A HA   1 
ATOM   2040 H HB2  . MET   A 1 136 ? 41.62632 -20.06024 16.08888 1.000 26.57888  ? 133 MET   A HB2  1 
ATOM   2041 H HB3  . MET   A 1 136 ? 43.01527 -20.78548 15.82379 1.000 26.57888  ? 133 MET   A HB3  1 
ATOM   2042 H HG2  . MET   A 1 136 ? 42.91254 -19.07744 14.34403 1.000 24.98692  ? 133 MET   A HG2  1 
ATOM   2043 H HG3  . MET   A 1 136 ? 42.64039 -20.38919 13.48925 1.000 24.98692  ? 133 MET   A HG3  1 
ATOM   2044 H HE1  . MET   A 1 136 ? 40.24807 -18.10427 11.73914 1.000 32.31660  ? 133 MET   A HE1  1 
ATOM   2045 H HE2  . MET   A 1 136 ? 41.60454 -17.55657 12.35843 1.000 32.31660  ? 133 MET   A HE2  1 
ATOM   2046 H HE3  . MET   A 1 136 ? 41.58239 -18.95615 11.60731 1.000 32.31660  ? 133 MET   A HE3  1 
ATOM   2047 N N    . MET   A 1 137 ? 43.11947 -23.64266 14.99514 1.000 27.58392  ? 134 MET   A N    1 
ATOM   2048 C CA   . MET   A 1 137 ? 44.06885 -24.42808 14.22367 1.000 29.43469  ? 134 MET   A CA   1 
ATOM   2049 C C    . MET   A 1 137 ? 43.58948 -25.84132 13.95025 1.000 27.45660  ? 134 MET   A C    1 
ATOM   2050 O O    . MET   A 1 137 ? 44.34176 -26.63335 13.37675 1.000 28.73332  ? 134 MET   A O    1 
ATOM   2051 C CB   . MET   A 1 137 ? 45.41441 -24.48195 14.95546 1.000 21.07181  ? 134 MET   A CB   1 
ATOM   2052 C CG   . MET   A 1 137 ? 46.16084 -23.16431 14.93465 1.000 23.62459  ? 134 MET   A CG   1 
ATOM   2053 S SD   . MET   A 1 137 ? 46.56174 -22.62489 13.26406 1.000 27.74899  ? 134 MET   A SD   1 
ATOM   2054 C CE   . MET   A 1 137 ? 47.66510 -23.94052 12.74875 1.000 28.13497  ? 134 MET   A CE   1 
ATOM   2055 H H    . MET   A 1 137 ? 43.20747 -23.72449 15.84670 1.000 33.11936  ? 134 MET   A H    1 
ATOM   2056 H HA   . MET   A 1 137 ? 44.20752 -23.98430 13.37236 1.000 35.34028  ? 134 MET   A HA   1 
ATOM   2057 H HB2  . MET   A 1 137 ? 45.25788 -24.72126 15.88236 1.000 25.30483  ? 134 MET   A HB2  1 
ATOM   2058 H HB3  . MET   A 1 137 ? 45.97581 -25.14931 14.53078 1.000 25.30483  ? 134 MET   A HB3  1 
ATOM   2059 H HG2  . MET   A 1 137 ? 45.60955 -22.48117 15.34732 1.000 28.36817  ? 134 MET   A HG2  1 
ATOM   2060 H HG3  . MET   A 1 137 ? 46.99107 -23.26254 15.42655 1.000 28.36817  ? 134 MET   A HG3  1 
ATOM   2061 H HE1  . MET   A 1 137 ? 48.05527 -23.70792 11.89168 1.000 33.78062  ? 134 MET   A HE1  1 
ATOM   2062 H HE2  . MET   A 1 137 ? 48.36418 -24.04475 13.41308 1.000 33.78062  ? 134 MET   A HE2  1 
ATOM   2063 H HE3  . MET   A 1 137 ? 47.15895 -24.76416 12.66917 1.000 33.78062  ? 134 MET   A HE3  1 
ATOM   2064 N N    . ASN   A 1 138 ? 42.36591 -26.17442 14.34337 1.000 26.18840  ? 135 ASN   A N    1 
ATOM   2065 C CA   . ASN   A 1 138 ? 41.82450 -27.50443 14.09760 1.000 24.05543  ? 135 ASN   A CA   1 
ATOM   2066 C C    . ASN   A 1 138 ? 41.77530 -27.76454 12.59526 1.000 18.44041  ? 135 ASN   A C    1 
ATOM   2067 O O    . ASN   A 1 138 ? 41.05033 -27.07786 11.86487 1.000 22.95547  ? 135 ASN   A O    1 
ATOM   2068 C CB   . ASN   A 1 138 ? 40.44098 -27.62792 14.73743 1.000 29.69887  ? 135 ASN   A CB   1 
ATOM   2069 C CG   . ASN   A 1 138 ? 39.88666 -29.04081 14.66973 1.000 45.18152  ? 135 ASN   A CG   1 
ATOM   2070 O OD1  . ASN   A 1 138 ? 40.60350 -29.98903 14.36153 1.000 58.61505  ? 135 ASN   A OD1  1 
ATOM   2071 N ND2  . ASN   A 1 138 ? 38.60527 -29.18434 14.97647 1.000 70.30138  ? 135 ASN   A ND2  1 
ATOM   2072 H H    . ASN   A 1 138 ? 41.82720 -25.64610 14.75600 1.000 31.44474  ? 135 ASN   A H    1 
ATOM   2073 H HA   . ASN   A 1 138 ? 42.38791 -28.18429 14.49916 1.000 28.88517  ? 135 ASN   A HA   1 
ATOM   2074 H HB2  . ASN   A 1 138 ? 40.50080 -27.37355 15.67157 1.000 35.65730  ? 135 ASN   A HB2  1 
ATOM   2075 H HB3  . ASN   A 1 138 ? 39.82416 -27.04106 14.27264 1.000 35.65730  ? 135 ASN   A HB3  1 
ATOM   2076 H HD21 . ASN   A 1 138 ? 38.24237 -29.96369 14.95375 1.000 84.38031  ? 135 ASN   A HD21 1 
ATOM   2077 H HD22 . ASN   A 1 138 ? 38.13672 -28.49813 15.19821 1.000 84.38031  ? 135 ASN   A HD22 1 
ATOM   2078 N N    . GLY   A 1 139 ? 42.56067 -28.73235 12.12072 1.000 23.56648  ? 136 GLY   A N    1 
ATOM   2079 C CA   . GLY   A 1 139 ? 42.65185 -29.03027 10.70727 1.000 20.52327  ? 136 GLY   A CA   1 
ATOM   2080 C C    . GLY   A 1 139 ? 43.84815 -28.42809 9.99208  1.000 27.72361  ? 136 GLY   A C    1 
ATOM   2081 O O    . GLY   A 1 139 ? 44.11809 -28.80276 8.84589  1.000 25.03786  ? 136 GLY   A O    1 
ATOM   2082 H H    A GLY   A 1 139 ? 43.05583 -29.23441 12.61300 0.550 28.29843  ? 136 GLY   A H    1 
ATOM   2083 H H    B GLY   A 1 139 ? 43.05583 -29.23441 12.61300 0.450 28.29843  ? 136 GLY   A H    1 
ATOM   2084 H HA2  . GLY   A 1 139 ? 42.69776 -29.99288 10.59697 1.000 24.64658  ? 136 GLY   A HA2  1 
ATOM   2085 H HA3  . GLY   A 1 139 ? 41.85148 -28.70010 10.26989 1.000 24.64658  ? 136 GLY   A HA3  1 
ATOM   2086 N N    . GLY   A 1 140 ? 44.56127 -27.50382 10.62317 1.000 19.94362  ? 137 GLY   A N    1 
ATOM   2087 C CA   . GLY   A 1 140 ? 45.69238 -26.87370 9.97374  1.000 21.04185  ? 137 GLY   A CA   1 
ATOM   2088 C C    . GLY   A 1 140 ? 45.34663 -26.01905 8.77232  1.000 22.86123  ? 137 GLY   A C    1 
ATOM   2089 O O    . GLY   A 1 140 ? 46.16304 -25.89398 7.85818  1.000 24.52972  ? 137 GLY   A O    1 
ATOM   2090 H H    . GLY   A 1 140 ? 44.40899 -27.22769 11.42327 1.000 23.95100  ? 137 GLY   A H    1 
ATOM   2091 H HA2  . GLY   A 1 140 ? 46.14415 -26.30710 10.61855 1.000 25.26888  ? 137 GLY   A HA2  1 
ATOM   2092 H HA3  . GLY   A 1 140 ? 46.30464 -27.56523 9.67737  1.000 25.26888  ? 137 GLY   A HA3  1 
ATOM   2093 N N    . HIS   A 1 141 ? 44.15973 -25.41833 8.75020  1.000 21.26595  ? 138 HIS   A N    1 
ATOM   2094 C CA   . HIS   A 1 141 ? 43.72545 -24.65915 7.58706  1.000 21.00338  ? 138 HIS   A CA   1 
ATOM   2095 C C    . HIS   A 1 141 ? 44.30088 -23.25578 7.53590  1.000 21.79795  ? 138 HIS   A C    1 
ATOM   2096 O O    . HIS   A 1 141 ? 44.17838 -22.59115 6.49730  1.000 26.53107  ? 138 HIS   A O    1 
ATOM   2097 C CB   . HIS   A 1 141 ? 42.19969 -24.57912 7.56075  1.000 25.45086  ? 138 HIS   A CB   1 
ATOM   2098 C CG   . HIS   A 1 141 ? 41.53698 -25.90548 7.38824  1.000 18.49831  ? 138 HIS   A CG   1 
ATOM   2099 N ND1  . HIS   A 1 141 ? 41.54630 -26.58846 6.19262  1.000 27.60738  ? 138 HIS   A ND1  1 
ATOM   2100 C CD2  . HIS   A 1 141 ? 40.83744 -26.67115 8.25652  1.000 28.81640  ? 138 HIS   A CD2  1 
ATOM   2101 C CE1  . HIS   A 1 141 ? 40.88077 -27.72048 6.33115  1.000 27.60642  ? 138 HIS   A CE1  1 
ATOM   2102 N NE2  . HIS   A 1 141 ? 40.44823 -27.79824 7.57721  1.000 29.03302  ? 138 HIS   A NE2  1 
ATOM   2103 H H    . HIS   A 1 141 ? 43.59116 -25.43669 9.39517  1.000 25.53779  ? 138 HIS   A H    1 
ATOM   2104 H HA   . HIS   A 1 141 ? 44.02135 -25.12610 6.79001  1.000 25.22272  ? 138 HIS   A HA   1 
ATOM   2105 H HB2  . HIS   A 1 141 ? 41.89178 -24.19986 8.39875  1.000 30.55969  ? 138 HIS   A HB2  1 
ATOM   2106 H HB3  . HIS   A 1 141 ? 41.92878 -24.01314 6.82104  1.000 30.55969  ? 138 HIS   A HB3  1 
ATOM   2107 H HD2  . HIS   A 1 141 ? 40.65466 -26.47142 9.14624  1.000 34.59834  ? 138 HIS   A HD2  1 
ATOM   2108 H HE1  . HIS   A 1 141 ? 40.74047 -28.35461 5.66549  1.000 33.14636  ? 138 HIS   A HE1  1 
ATOM   2109 H HE2  . HIS   A 1 141 ? 39.99578 -28.45001 7.90901  0.245 34.85828  ? 138 HIS   A HE2  1 
ATOM   2110 N N    . TYR   A 1 142 ? 44.90188 -22.79234 8.62384  1.000 22.94174  ? 139 TYR   A N    1 
ATOM   2111 C CA   . TYR   A 1 142 ? 45.54498 -21.49633 8.70329  1.000 19.02993  ? 139 TYR   A CA   1 
ATOM   2112 C C    . TYR   A 1 142 ? 46.95688 -21.70060 9.21907  1.000 21.93607  ? 139 TYR   A C    1 
ATOM   2113 O O    . TYR   A 1 142 ? 47.29948 -22.75779 9.74983  1.000 23.96194  ? 139 TYR   A O    1 
ATOM   2114 C CB   . TYR   A 1 142 ? 44.82062 -20.53059 9.65267  1.000 21.27086  ? 139 TYR   A CB   1 
ATOM   2115 C CG   . TYR   A 1 142 ? 43.35429 -20.36179 9.37373  1.000 27.84999  ? 139 TYR   A CG   1 
ATOM   2116 C CD1  . TYR   A 1 142 ? 42.90896 -19.40208 8.49303  1.000 22.50108  ? 139 TYR   A CD1  1 
ATOM   2117 C CD2  . TYR   A 1 142 ? 42.41804 -21.16596 9.99985  1.000 25.42892  ? 139 TYR   A CD2  1 
ATOM   2118 C CE1  . TYR   A 1 142 ? 41.58563 -19.24592 8.23351  1.000 27.32002  ? 139 TYR   A CE1  1 
ATOM   2119 C CE2  . TYR   A 1 142 ? 41.08326 -21.01705 9.75035  1.000 25.42173  ? 139 TYR   A CE2  1 
ATOM   2120 C CZ   . TYR   A 1 142 ? 40.67164 -20.05213 8.86730  1.000 24.59089  ? 139 TYR   A CZ   1 
ATOM   2121 O OH   . TYR   A 1 142 ? 39.33985 -19.89678 8.60431  1.000 24.23984  ? 139 TYR   A OH   1 
ATOM   2122 H H    A TYR   A 1 142 ? 44.95045 -23.23342 9.36052  0.530 27.54874  ? 139 TYR   A H    1 
ATOM   2123 H H    B TYR   A 1 142 ? 44.95045 -23.23342 9.36052  0.470 27.54874  ? 139 TYR   A H    1 
ATOM   2124 H HA   . TYR   A 1 142 ? 45.55272 -21.10267 7.81680  1.000 22.85457  ? 139 TYR   A HA   1 
ATOM   2125 H HB2  . TYR   A 1 142 ? 44.90939 -20.86435 10.55910 1.000 25.54369  ? 139 TYR   A HB2  1 
ATOM   2126 H HB3  . TYR   A 1 142 ? 45.23489 -19.65661 9.57889  1.000 25.54369  ? 139 TYR   A HB3  1 
ATOM   2127 H HD1  . TYR   A 1 142 ? 43.52577 -18.85076 8.06818  1.000 27.01995  ? 139 TYR   A HD1  1 
ATOM   2128 H HD2  . TYR   A 1 142 ? 42.70191 -21.81763 10.59956 1.000 30.53336  ? 139 TYR   A HD2  1 
ATOM   2129 H HE1  . TYR   A 1 142 ? 41.29987 -18.59774 7.63092  1.000 32.80268  ? 139 TYR   A HE1  1 
ATOM   2130 H HE2  . TYR   A 1 142 ? 40.46135 -21.56339 10.17420 1.000 30.52473  ? 139 TYR   A HE2  1 
ATOM   2131 H HH   . TYR   A 1 142 ? 39.21982 -19.22270 8.11768  1.000 29.10646  ? 139 TYR   A HH   1 
ATOM   2132 N N    . THR   A 1 143 ? 47.76033 -20.65908 9.08193  1.000 22.33984  ? 140 THR   A N    1 
ATOM   2133 C CA   . THR   A 1 143 ? 49.07715 -20.57246 9.69471  1.000 25.77127  ? 140 THR   A CA   1 
ATOM   2134 C C    . THR   A 1 143 ? 49.01285 -19.57084 10.83893 1.000 27.00636  ? 140 THR   A C    1 
ATOM   2135 O O    . THR   A 1 143 ? 48.47990 -18.46614 10.68725 1.000 26.34885  ? 140 THR   A O    1 
ATOM   2136 C CB   . THR   A 1 143 ? 50.12159 -20.17768 8.65480  1.000 27.69593  ? 140 THR   A CB   1 
ATOM   2137 O OG1  . THR   A 1 143 ? 50.19089 -21.21640 7.66573  1.000 30.93560  ? 140 THR   A OG1  1 
ATOM   2138 C CG2  . THR   A 1 143 ? 51.47454 -20.01740 9.28143  1.000 26.55484  ? 140 THR   A CG2  1 
ATOM   2139 H H    . THR   A 1 143 ? 47.55786 -19.96210 8.62059  1.000 26.82646  ? 140 THR   A H    1 
ATOM   2140 H HA   . THR   A 1 143 ? 49.34599 -21.42747 10.06563 1.000 30.94418  ? 140 THR   A HA   1 
ATOM   2141 H HB   . THR   A 1 143 ? 49.87632 -19.33091 8.25018  1.000 33.25378  ? 140 THR   A HB   1 
ATOM   2142 H HG1  . THR   A 1 143 ? 50.72500 -20.99702 7.05566  1.000 37.14137  ? 140 THR   A HG1  1 
ATOM   2143 H HG21 . THR   A 1 143 ? 52.15040 -19.92320 8.59206  1.000 31.88447  ? 140 THR   A HG21 1 
ATOM   2144 H HG22 . THR   A 1 143 ? 51.48769 -19.22810 9.84511  1.000 31.88447  ? 140 THR   A HG22 1 
ATOM   2145 H HG23 . THR   A 1 143 ? 51.68348 -20.79453 9.82303  1.000 31.88447  ? 140 THR   A HG23 1 
ATOM   2146 N N    . TYR   A 1 144 ? 49.52019 -19.97099 11.99063 1.000 21.32902  ? 141 TYR   A N    1 
ATOM   2147 C CA   . TYR   A 1 144 ? 49.33132 -19.19364 13.20401 1.000 23.79627  ? 141 TYR   A CA   1 
ATOM   2148 C C    . TYR   A 1 144 ? 50.44535 -18.17943 13.38414 1.000 25.81626  ? 141 TYR   A C    1 
ATOM   2149 O O    . TYR   A 1 144 ? 51.60229 -18.44919 13.07347 1.000 26.57580  ? 141 TYR   A O    1 
ATOM   2150 C CB   . TYR   A 1 144 ? 49.26949 -20.11022 14.42039 1.000 23.43977  ? 141 TYR   A CB   1 
ATOM   2151 C CG   . TYR   A 1 144 ? 48.63290 -19.43376 15.60587 1.000 22.84972  ? 141 TYR   A CG   1 
ATOM   2152 C CD1  . TYR   A 1 144 ? 47.26109 -19.22232 15.64867 1.000 26.25513  ? 141 TYR   A CD1  1 
ATOM   2153 C CD2  . TYR   A 1 144 ? 49.40146 -18.97912 16.66058 1.000 27.41793  ? 141 TYR   A CD2  1 
ATOM   2154 C CE1  . TYR   A 1 144 ? 46.66854 -18.59664 16.72533 1.000 28.63356  ? 141 TYR   A CE1  1 
ATOM   2155 C CE2  . TYR   A 1 144 ? 48.81785 -18.34794 17.74666 1.000 27.14954  ? 141 TYR   A CE2  1 
ATOM   2156 C CZ   . TYR   A 1 144 ? 47.45502 -18.17023 17.76719 1.000 24.85142  ? 141 TYR   A CZ   1 
ATOM   2157 O OH   . TYR   A 1 144 ? 46.86898 -17.55010 18.82807 1.000 23.42936  ? 141 TYR   A OH   1 
ATOM   2158 H H    . TYR   A 1 144 ? 49.97895 -20.69057 12.09718 1.000 25.61348  ? 141 TYR   A H    1 
ATOM   2159 H HA   . TYR   A 1 144 ? 48.49501 -18.70699 13.13577 1.000 28.57418  ? 141 TYR   A HA   1 
ATOM   2160 H HB2  . TYR   A 1 144 ? 48.74415 -20.89557 14.20101 1.000 28.14638  ? 141 TYR   A HB2  1 
ATOM   2161 H HB3  . TYR   A 1 144 ? 50.17008 -20.37204 14.66798 1.000 28.14638  ? 141 TYR   A HB3  1 
ATOM   2162 H HD1  . TYR   A 1 144 ? 46.73259 -19.50772 14.93864 1.000 31.52481  ? 141 TYR   A HD1  1 
ATOM   2163 H HD2  . TYR   A 1 144 ? 50.32354 -19.09864 16.64086 1.000 32.92018  ? 141 TYR   A HD2  1 
ATOM   2164 H HE1  . TYR   A 1 144 ? 45.74810 -18.46516 16.74559 1.000 34.37893  ? 141 TYR   A HE1  1 
ATOM   2165 H HE2  . TYR   A 1 144 ? 49.34204 -18.04785 18.45382 1.000 32.59810  ? 141 TYR   A HE2  1 
ATOM   2166 H HH   . TYR   A 1 144 ? 46.03431 -17.54668 18.73367 1.000 28.13389  ? 141 TYR   A HH   1 
ATOM   2167 N N    A SER   A 1 145 ? 50.08339 -17.01063 13.89601 0.746 23.32444  ? 142 SER   A N    1 
ATOM   2168 N N    B SER   A 1 145 ? 50.07830 -17.00059 13.87701 0.254 23.48407  ? 142 SER   A N    1 
ATOM   2169 C CA   A SER   A 1 145 ? 51.02667 -15.94872 14.20350 0.746 25.57812  ? 142 SER   A CA   1 
ATOM   2170 C CA   B SER   A 1 145 ? 51.04273 -15.95272 14.18932 0.254 25.56893  ? 142 SER   A CA   1 
ATOM   2171 C C    A SER   A 1 145 ? 50.80354 -15.49306 15.63658 0.746 25.22800  ? 142 SER   A C    1 
ATOM   2172 C C    B SER   A 1 145 ? 50.80765 -15.45631 15.61185 0.254 25.29904  ? 142 SER   A C    1 
ATOM   2173 O O    A SER   A 1 145 ? 49.68465 -15.55630 16.15566 0.746 26.71764  ? 142 SER   A O    1 
ATOM   2174 O O    B SER   A 1 145 ? 49.67420 -15.45097 16.09549 0.254 26.43528  ? 142 SER   A O    1 
ATOM   2175 C CB   A SER   A 1 145 ? 50.85912 -14.76638 13.25056 0.746 23.55105  ? 142 SER   A CB   1 
ATOM   2176 C CB   B SER   A 1 145 ? 50.93230 -14.79314 13.20426 0.254 23.50357  ? 142 SER   A CB   1 
ATOM   2177 O OG   A SER   A 1 145 ? 51.52933 -13.61338 13.73272 0.746 20.79364  ? 142 SER   A OG   1 
ATOM   2178 O OG   B SER   A 1 145 ? 49.67515 -14.15070 13.30931 0.254 31.13781  ? 142 SER   A OG   1 
ATOM   2179 H H    A SER   A 1 145 ? 49.26921 -16.80332 14.07969 0.746 28.00798  ? 142 SER   A H    1 
ATOM   2180 H H    B SER   A 1 145 ? 49.26363 -16.77991 14.04198 0.254 28.19954  ? 142 SER   A H    1 
ATOM   2181 H HA   A SER   A 1 145 ? 51.93637 -16.27508 14.12084 0.746 30.71240  ? 142 SER   A HA   1 
ATOM   2182 H HA   B SER   A 1 145 ? 51.94357 -16.30478 14.11554 0.254 30.70137  ? 142 SER   A HA   1 
ATOM   2183 H HB2  A SER   A 1 145 ? 51.22904 -15.00550 12.38634 0.746 28.27992  ? 142 SER   A HB2  1 
ATOM   2184 H HB2  B SER   A 1 145 ? 51.63157 -14.14913 13.39707 0.254 28.22294  ? 142 SER   A HB2  1 
ATOM   2185 H HB3  A SER   A 1 145 ? 49.91411 -14.56592 13.16295 0.746 28.27992  ? 142 SER   A HB3  1 
ATOM   2186 H HB3  B SER   A 1 145 ? 51.03603 -15.13554 12.30265 0.254 28.22294  ? 142 SER   A HB3  1 
ATOM   2187 H HG   A SER   A 1 145 ? 51.39587 -12.96579 13.21463 0.746 24.97102  ? 142 SER   A HG   1 
ATOM   2188 H HG   B SER   A 1 145 ? 49.63414 -13.71511 14.02638 0.254 37.38402  ? 142 SER   A HG   1 
ATOM   2189 N N    . GLU   A 1 146 ? 51.87883 -15.03521 16.27351 1.000 26.65842  ? 143 GLU   A N    1 
ATOM   2190 C CA   A GLU   A 1 146 ? 51.80289 -14.47945 17.61701 0.459 29.05152  ? 143 GLU   A CA   1 
ATOM   2191 C CA   C GLU   A 1 146 ? 51.76492 -14.47792 17.60899 0.541 29.03675  ? 143 GLU   A CA   1 
ATOM   2192 C C    . GLU   A 1 146 ? 51.90918 -12.95886 17.61159 1.000 31.13352  ? 143 GLU   A C    1 
ATOM   2193 O O    . GLU   A 1 146 ? 52.10087 -12.34945 18.67067 1.000 27.38543  ? 143 GLU   A O    1 
ATOM   2194 C CB   A GLU   A 1 146 ? 52.89331 -15.08310 18.50988 0.459 28.32035  ? 143 GLU   A CB   1 
ATOM   2195 C CB   C GLU   A 1 146 ? 52.81770 -15.10728 18.52853 0.541 28.52452  ? 143 GLU   A CB   1 
ATOM   2196 C CG   A GLU   A 1 146 ? 52.76814 -16.59597 18.73322 0.459 49.68252  ? 143 GLU   A CG   1 
ATOM   2197 C CG   C GLU   A 1 146 ? 52.66017 -16.61125 18.69767 0.541 49.64437  ? 143 GLU   A CG   1 
ATOM   2198 C CD   A GLU   A 1 146 ? 52.36526 -16.98698 20.15994 0.459 39.20765  ? 143 GLU   A CD   1 
ATOM   2199 C CD   C GLU   A 1 146 ? 53.78775 -17.24798 19.49063 0.541 34.44176  ? 143 GLU   A CD   1 
ATOM   2200 O OE1  A GLU   A 1 146 ? 52.34965 -16.12070 21.06334 0.459 61.14193  ? 143 GLU   A OE1  1 
ATOM   2201 O OE1  C GLU   A 1 146 ? 54.55040 -16.51855 20.15791 0.541 44.40774  ? 143 GLU   A OE1  1 
ATOM   2202 O OE2  A GLU   A 1 146 ? 52.06077 -18.18070 20.37923 0.459 49.69327  ? 143 GLU   A OE2  1 
ATOM   2203 O OE2  C GLU   A 1 146 ? 53.90566 -18.48809 19.44469 0.541 58.19416  ? 143 GLU   A OE2  1 
ATOM   2204 H H    A GLU   A 1 146 ? 52.67226 -15.03695 15.94175 0.746 32.00876  ? 143 GLU   A H    1 
ATOM   2205 H HA   A GLU   A 1 146 ? 50.94761 -14.72098 18.00566 0.459 34.88048  ? 143 GLU   A HA   1 
ATOM   2206 H HA   C GLU   A 1 146 ? 50.88221 -14.68143 17.95585 0.541 34.86275  ? 143 GLU   A HA   1 
ATOM   2207 H HB2  A GLU   A 1 146 ? 53.75598 -14.91820 18.09815 0.459 34.00308  ? 143 GLU   A HB2  1 
ATOM   2208 H HB2  C GLU   A 1 146 ? 53.69748 -14.94140 18.15519 0.541 34.24808  ? 143 GLU   A HB2  1 
ATOM   2209 H HB3  A GLU   A 1 146 ? 52.85317 -14.65440 19.37907 0.459 34.00308  ? 143 GLU   A HB3  1 
ATOM   2210 H HB3  C GLU   A 1 146 ? 52.74799 -14.70120 19.40667 0.541 34.24808  ? 143 GLU   A HB3  1 
ATOM   2211 H HG2  A GLU   A 1 146 ? 52.09244 -16.94434 18.13077 0.459 59.63768  ? 143 GLU   A HG2  1 
ATOM   2212 H HG2  C GLU   A 1 146 ? 51.82956 -16.78926 19.16597 0.541 59.59190  ? 143 GLU   A HG2  1 
ATOM   2213 H HG3  A GLU   A 1 146 ? 53.62509 -17.00990 18.54560 0.459 59.63768  ? 143 GLU   A HG3  1 
ATOM   2214 H HG3  C GLU   A 1 146 ? 52.64204 -17.02564 17.82083 0.541 59.59190  ? 143 GLU   A HG3  1 
ATOM   2215 N N    . ASN   A 1 147 ? 51.79835 -12.33454 16.44333 1.000 29.74789  ? 144 ASN   A N    1 
ATOM   2216 C CA   . ASN   A 1 147 ? 51.80655 -10.87825 16.37287 1.000 23.26477  ? 144 ASN   A CA   1 
ATOM   2217 C C    . ASN   A 1 147 ? 50.52372 -10.29631 16.96626 1.000 26.55613  ? 144 ASN   A C    1 
ATOM   2218 O O    . ASN   A 1 147 ? 49.43806 -10.87614 16.85804 1.000 25.40780  ? 144 ASN   A O    1 
ATOM   2219 C CB   . ASN   A 1 147 ? 51.95402 -10.42438 14.92379 1.000 27.60858  ? 144 ASN   A CB   1 
ATOM   2220 C CG   . ASN   A 1 147 ? 53.38191 -10.49826 14.42773 1.000 36.27665  ? 144 ASN   A CG   1 
ATOM   2221 O OD1  . ASN   A 1 147 ? 54.33075 -10.53841 15.20660 1.000 35.52557  ? 144 ASN   A OD1  1 
ATOM   2222 N ND2  . ASN   A 1 147 ? 53.53753 -10.49973 13.12096 1.000 45.32167  ? 144 ASN   A ND2  1 
ATOM   2223 H H    . ASN   A 1 147 ? 51.71780 -12.72796 15.68284 1.000 35.71613  ? 144 ASN   A H    1 
ATOM   2224 H HA   . ASN   A 1 147 ? 52.55748 -10.53620 16.88279 1.000 27.93638  ? 144 ASN   A HA   1 
ATOM   2225 H HB2  . ASN   A 1 147 ? 51.41025 -10.99408 14.35752 1.000 33.14895  ? 144 ASN   A HB2  1 
ATOM   2226 H HB3  . ASN   A 1 147 ? 51.65832 -9.50354  14.84962 1.000 33.14895  ? 144 ASN   A HB3  1 
ATOM   2227 H HD21 . ASN   A 1 147 ? 54.32686 -10.54023 12.78197 1.000 54.40466  ? 144 ASN   A HD21 1 
ATOM   2228 H HD22 . ASN   A 1 147 ? 52.84990 -10.46020 12.60599 1.000 54.40466  ? 144 ASN   A HD22 1 
ATOM   2229 N N    . ARG   A 1 148 ? 50.64750 -9.12157  17.58141 1.000 25.12191  ? 145 ARG   A N    1 
ATOM   2230 C CA   . ARG   A 1 148 ? 49.48966 -8.53519  18.24637 1.000 26.34175  ? 145 ARG   A CA   1 
ATOM   2231 C C    . ARG   A 1 148 ? 48.40395 -8.18634  17.24837 1.000 24.83041  ? 145 ARG   A C    1 
ATOM   2232 O O    . ARG   A 1 148 ? 47.21064 -8.31439  17.55633 1.000 20.92672  ? 145 ARG   A O    1 
ATOM   2233 C CB   . ARG   A 1 148 ? 49.92042 -7.30584  19.04318 1.000 26.71304  ? 145 ARG   A CB   1 
ATOM   2234 C CG   . ARG   A 1 148 ? 50.89471 -7.64141  20.16534 1.000 35.41273  ? 145 ARG   A CG   1 
ATOM   2235 C CD   . ARG   A 1 148 ? 51.43261 -6.39000  20.82296 1.000 33.05978  ? 145 ARG   A CD   1 
ATOM   2236 N NE   . ARG   A 1 148 ? 50.35930 -5.57643  21.38384 1.000 32.69714  ? 145 ARG   A NE   1 
ATOM   2237 C CZ   . ARG   A 1 148 ? 49.79763 -5.79078  22.56718 1.000 29.76837  ? 145 ARG   A CZ   1 
ATOM   2238 N NH1  . ARG   A 1 148 ? 50.14073 -6.82596  23.31649 1.000 30.48029  ? 145 ARG   A NH1  1 
ATOM   2239 N NH2  . ARG   A 1 148 ? 48.87341 -4.94283  23.01229 1.000 30.98522  ? 145 ARG   A NH2  1 
ATOM   2240 H H    . ARG   A 1 148 ? 51.37010 -8.65746  17.62674 1.000 30.16495  ? 145 ARG   A H    1 
ATOM   2241 H HA   . ARG   A 1 148 ? 49.11730 -9.17409  18.87411 1.000 31.62876  ? 145 ARG   A HA   1 
ATOM   2242 H HB2  . ARG   A 1 148 ? 50.35601 -6.67877  18.44490 1.000 32.07430  ? 145 ARG   A HB2  1 
ATOM   2243 H HB3  . ARG   A 1 148 ? 49.13572 -6.89584  19.43948 1.000 32.07430  ? 145 ARG   A HB3  1 
ATOM   2244 H HG2  . ARG   A 1 148 ? 50.43895 -8.16880  20.83990 1.000 42.51393  ? 145 ARG   A HG2  1 
ATOM   2245 H HG3  . ARG   A 1 148 ? 51.64280 -8.14131  19.80289 1.000 42.51393  ? 145 ARG   A HG3  1 
ATOM   2246 H HD2  . ARG   A 1 148 ? 52.03447 -6.63853  21.54191 1.000 39.69039  ? 145 ARG   A HD2  1 
ATOM   2247 H HD3  . ARG   A 1 148 ? 51.90529 -5.85857  20.16337 1.000 39.69039  ? 145 ARG   A HD3  1 
ATOM   2248 H HE   . ARG   A 1 148 ? 50.07148 -4.91412  20.91682 1.000 39.25522  ? 145 ARG   A HE   1 
ATOM   2249 H HH11 . ARG   A 1 148 ? 50.73964 -7.37753  23.03957 1.000 36.59500  ? 145 ARG   A HH11 1 
ATOM   2250 H HH12 . ARG   A 1 148 ? 49.76483 -6.94721  24.08042 1.000 36.59500  ? 145 ARG   A HH12 1 
ATOM   2251 H HH21 . ARG   A 1 148 ? 48.64611 -4.26486  22.53450 1.000 37.20092  ? 145 ARG   A HH21 1 
ATOM   2252 H HH22 . ARG   A 1 148 ? 48.50351 -5.07287  23.77771 1.000 37.20092  ? 145 ARG   A HH22 1 
ATOM   2253 N N    . VAL   A 1 149 ? 48.79983 -7.77298  16.05115 1.000 23.56958  ? 146 VAL   A N    1 
ATOM   2254 C CA   . VAL   A 1 149 ? 47.89771 -7.56792  14.92600 1.000 26.28623  ? 146 VAL   A CA   1 
ATOM   2255 C C    . VAL   A 1 149 ? 48.51529 -8.28605  13.74049 1.000 27.09588  ? 146 VAL   A C    1 
ATOM   2256 O O    . VAL   A 1 149 ? 49.71956 -8.16223  13.50267 1.000 27.72300  ? 146 VAL   A O    1 
ATOM   2257 C CB   . VAL   A 1 149 ? 47.69403 -6.08336  14.58158 1.000 20.46777  ? 146 VAL   A CB   1 
ATOM   2258 C CG1  . VAL   A 1 149 ? 46.76732 -5.94179  13.37709 1.000 29.50198  ? 146 VAL   A CG1  1 
ATOM   2259 C CG2  . VAL   A 1 149 ? 47.13334 -5.33026  15.74459 1.000 25.76951  ? 146 VAL   A CG2  1 
ATOM   2260 H H    . VAL   A 1 149 ? 49.61950 -7.59770  15.85873 1.000 28.30215  ? 146 VAL   A H    1 
ATOM   2261 H HA   . VAL   A 1 149 ? 47.02801 -7.94134  15.13830 1.000 31.56213  ? 146 VAL   A HA   1 
ATOM   2262 H HB   . VAL   A 1 149 ? 48.55833 -5.70101  14.36322 1.000 24.57998  ? 146 VAL   A HB   1 
ATOM   2263 H HG11 . VAL   A 1 149 ? 46.59461 -5.00023  13.22045 1.000 35.42104  ? 146 VAL   A HG11 1 
ATOM   2264 H HG12 . VAL   A 1 149 ? 47.19697 -6.33297  12.60037 1.000 35.42104  ? 146 VAL   A HG12 1 
ATOM   2265 H HG13 . VAL   A 1 149 ? 45.93516 -6.40431  13.56279 1.000 35.42104  ? 146 VAL   A HG13 1 
ATOM   2266 H HG21 . VAL   A 1 149 ? 46.98156 -4.40923  15.48087 1.000 30.94207  ? 146 VAL   A HG21 1 
ATOM   2267 H HG22 . VAL   A 1 149 ? 46.29583 -5.74006  16.01206 1.000 30.94207  ? 146 VAL   A HG22 1 
ATOM   2268 H HG23 . VAL   A 1 149 ? 47.76726 -5.36416  16.47801 1.000 30.94207  ? 146 VAL   A HG23 1 
ATOM   2269 N N    . GLU   A 1 150 ? 47.70265 -9.02299  13.00255 1.000 29.39488  ? 147 GLU   A N    1 
ATOM   2270 C CA   . GLU   A 1 150 ? 48.16338 -9.74953  11.83594 1.000 22.84626  ? 147 GLU   A CA   1 
ATOM   2271 C C    . GLU   A 1 150 ? 47.24646 -9.43768  10.66382 1.000 22.17913  ? 147 GLU   A C    1 
ATOM   2272 O O    . GLU   A 1 150 ? 46.02091 -9.49068  10.79425 1.000 23.40962  ? 147 GLU   A O    1 
ATOM   2273 C CB   . GLU   A 1 150 ? 48.20215 -11.25193 12.12149 1.000 24.52261  ? 147 GLU   A CB   1 
ATOM   2274 C CG   . GLU   A 1 150 ? 48.88751 -12.06029 11.04606 1.000 32.58755  ? 147 GLU   A CG   1 
ATOM   2275 C CD   . GLU   A 1 150 ? 50.35609 -11.68015 10.86124 1.000 26.43439  ? 147 GLU   A CD   1 
ATOM   2276 O OE1  . GLU   A 1 150 ? 51.18564 -12.01798 11.73192 1.000 33.80402  ? 147 GLU   A OE1  1 
ATOM   2277 O OE2  . GLU   A 1 150 ? 50.67295 -11.03042 9.84035  1.000 39.33023  ? 147 GLU   A OE2  1 
ATOM   2278 H H    . GLU   A 1 150 ? 46.86299 -9.11896  13.16180 1.000 35.29251  ? 147 GLU   A H    1 
ATOM   2279 H HA   . GLU   A 1 150 ? 49.05783 -9.46454  11.59174 1.000 27.43417  ? 147 GLU   A HA   1 
ATOM   2280 H HB2  . GLU   A 1 150 ? 48.68092 -11.39879 12.95222 1.000 29.44579  ? 147 GLU   A HB2  1 
ATOM   2281 H HB3  . GLU   A 1 150 ? 47.29185 -11.57737 12.20121 1.000 29.44579  ? 147 GLU   A HB3  1 
ATOM   2282 H HG2  . GLU   A 1 150 ? 48.84925 -12.99968 11.28478 1.000 39.12372  ? 147 GLU   A HG2  1 
ATOM   2283 H HG3  . GLU   A 1 150 ? 48.43188 -11.91356 10.20240 1.000 39.12372  ? 147 GLU   A HG3  1 
ATOM   2284 N N    . LYS   A 1 151 ? 47.84324 -9.12007  9.51727  1.000 27.27238  ? 148 LYS   A N    1 
ATOM   2285 C CA   . LYS   A 1 151 ? 47.09270 -8.83971  8.29960  1.000 31.27112  ? 148 LYS   A CA   1 
ATOM   2286 C C    . LYS   A 1 151 ? 47.69038 -9.64392  7.15467  1.000 27.70254  ? 148 LYS   A C    1 
ATOM   2287 O O    . LYS   A 1 151 ? 48.86580 -9.46788  6.81523  1.000 33.46237  ? 148 LYS   A O    1 
ATOM   2288 C CB   . LYS   A 1 151 ? 47.10452 -7.34360  7.97661  1.000 31.14762  ? 148 LYS   A CB   1 
ATOM   2289 C CG   . LYS   A 1 151 ? 46.16076 -6.94853  6.83465  1.000 32.55775  ? 148 LYS   A CG   1 
ATOM   2290 C CD   . LYS   A 1 151 ? 46.24228 -5.45256  6.53575  1.000 45.12034  ? 148 LYS   A CD   1 
ATOM   2291 C CE   . LYS   A 1 151 ? 45.36232 -5.06661  5.35174  1.000 45.25713  ? 148 LYS   A CE   1 
ATOM   2292 N NZ   . LYS   A 1 151 ? 45.69122 -5.81661  4.09698  1.000 70.24384  ? 148 LYS   A NZ   1 
ATOM   2293 H H    A LYS   A 1 151 ? 48.69563 -9.06016  9.42008  0.340 32.74551  ? 148 LYS   A H    1 
ATOM   2294 H H    B LYS   A 1 151 ? 48.69563 -9.06016  9.42008  0.660 32.74551  ? 148 LYS   A H    1 
ATOM   2295 H HA   . LYS   A 1 151 ? 46.17156 -9.12038  8.41636  1.000 37.54400  ? 148 LYS   A HA   1 
ATOM   2296 H HB2  . LYS   A 1 151 ? 46.83356 -6.85203  8.76771  1.000 37.39580  ? 148 LYS   A HB2  1 
ATOM   2297 H HB3  . LYS   A 1 151 ? 48.00397 -7.08771  7.71890  1.000 37.39580  ? 148 LYS   A HB3  1 
ATOM   2298 H HG2  . LYS   A 1 151 ? 46.40663 -7.43403  6.03169  1.000 39.08795  ? 148 LYS   A HG2  1 
ATOM   2299 H HG3  . LYS   A 1 151 ? 45.24769 -7.16061  7.08408  1.000 39.08795  ? 148 LYS   A HG3  1 
ATOM   2300 H HD2  . LYS   A 1 151 ? 45.94361 -4.95363  7.31213  1.000 54.16306  ? 148 LYS   A HD2  1 
ATOM   2301 H HD3  . LYS   A 1 151 ? 47.15897 -5.21751  6.32285  1.000 54.16306  ? 148 LYS   A HD3  1 
ATOM   2302 H HE2  . LYS   A 1 151 ? 44.43676 -5.25228  5.57483  1.000 54.32721  ? 148 LYS   A HE2  1 
ATOM   2303 H HE3  . LYS   A 1 151 ? 45.47663 -4.12050  5.17092  1.000 54.32721  ? 148 LYS   A HE3  1 
ATOM   2304 H HZ1  . LYS   A 1 151 ? 45.51630 -6.68251  4.20520  1.000 84.31126  ? 148 LYS   A HZ1  1 
ATOM   2305 H HZ2  . LYS   A 1 151 ? 45.20402 -5.50591  3.42007  1.000 84.31126  ? 148 LYS   A HZ2  1 
ATOM   2306 H HZ3  . LYS   A 1 151 ? 46.55380 -5.71849  3.90094  1.000 84.31126  ? 148 LYS   A HZ3  1 
ATOM   2307 N N    . ASP   A 1 152 ? 46.89242 -10.53432 6.57918  1.000 26.99103  ? 149 ASP   A N    1 
ATOM   2308 C CA   . ASP   A 1 152 ? 47.31919 -11.36871 5.46205  1.000 33.25981  ? 149 ASP   A CA   1 
ATOM   2309 C C    . ASP   A 1 152 ? 46.23240 -11.25334 4.40513  1.000 37.71302  ? 149 ASP   A C    1 
ATOM   2310 O O    . ASP   A 1 152 ? 45.10898 -11.72392 4.61270  1.000 32.15643  ? 149 ASP   A O    1 
ATOM   2311 C CB   . ASP   A 1 152 ? 47.52701 -12.82193 5.87914  1.000 29.33095  ? 149 ASP   A CB   1 
ATOM   2312 C CG   . ASP   A 1 152 ? 48.23196 -13.63570 4.81155  1.000 33.54416  ? 149 ASP   A CG   1 
ATOM   2313 O OD1  . ASP   A 1 152 ? 48.80379 -13.03065 3.87732  1.000 36.67355  ? 149 ASP   A OD1  1 
ATOM   2314 O OD2  . ASP   A 1 152 ? 48.21996 -14.88011 4.90531  1.000 31.69627  ? 149 ASP   A OD2  1 
ATOM   2315 H H    . ASP   A 1 152 ? 46.08030 -10.67708 6.82349  1.000 32.40789  ? 149 ASP   A H    1 
ATOM   2316 H HA   . ASP   A 1 152 ? 48.16401 -11.05001 5.10762  1.000 39.93042  ? 149 ASP   A HA   1 
ATOM   2317 H HB2  . ASP   A 1 152 ? 48.06858 -12.84680 6.68350  1.000 35.21580  ? 149 ASP   A HB2  1 
ATOM   2318 H HB3  . ASP   A 1 152 ? 46.66343 -13.23017 6.04788  1.000 35.21580  ? 149 ASP   A HB3  1 
ATOM   2319 N N    . GLY   A 1 153 ? 46.55514 -10.61121 3.29484  1.000 56.12488  ? 150 GLY   A N    1 
ATOM   2320 C CA   . GLY   A 1 153 ? 45.54556 -10.38323 2.27648  1.000 82.21749  ? 150 GLY   A CA   1 
ATOM   2321 C C    . GLY   A 1 153 ? 44.43676 -9.52355  2.85157  1.000 32.24644  ? 150 GLY   A C    1 
ATOM   2322 O O    . GLY   A 1 153 ? 44.67700 -8.43559  3.38487  1.000 37.81017  ? 150 GLY   A O    1 
ATOM   2323 H H    . GLY   A 1 153 ? 47.33613 -10.30276 3.10904  1.000 67.36851  ? 150 GLY   A H    1 
ATOM   2324 H HA2  . GLY   A 1 153 ? 45.93757 -9.92876  1.51446  1.000 98.67964  ? 150 GLY   A HA2  1 
ATOM   2325 H HA3  . GLY   A 1 153 ? 45.17224 -11.22875 1.98216  1.000 98.67964  ? 150 GLY   A HA3  1 
ATOM   2326 N N    . LEU   A 1 154 ? 43.20846 -10.02817 2.78175  1.000 38.18551  ? 151 LEU   A N    1 
ATOM   2327 C CA   . LEU   A 1 154 ? 42.03742 -9.30458  3.24962  1.000 39.49096  ? 151 LEU   A CA   1 
ATOM   2328 C C    . LEU   A 1 154 ? 41.57644 -9.75619  4.64030  1.000 43.57185  ? 151 LEU   A C    1 
ATOM   2329 O O    . LEU   A 1 154 ? 40.48292 -9.37309  5.07530  1.000 26.45151  ? 151 LEU   A O    1 
ATOM   2330 C CB   . LEU   A 1 154 ? 40.90814 -9.45121  2.22276  1.000 55.86917  ? 151 LEU   A CB   1 
ATOM   2331 C CG   . LEU   A 1 154 ? 40.32182 -10.85024 2.00333  1.000 76.05467  ? 151 LEU   A CG   1 
ATOM   2332 C CD1  . LEU   A 1 154 ? 39.13408 -11.11096 2.93118  1.000 73.49561  ? 151 LEU   A CD1  1 
ATOM   2333 C CD2  . LEU   A 1 154 ? 39.90308 -11.05340 0.55448  1.000 63.40318  ? 151 LEU   A CD2  1 
ATOM   2334 H H    . LEU   A 1 154 ? 43.02708 -10.80481 2.45997  1.000 45.84126  ? 151 LEU   A H    1 
ATOM   2335 H HA   . LEU   A 1 154 ? 42.25240 -8.36148  3.32205  1.000 47.40780  ? 151 LEU   A HA   1 
ATOM   2336 H HB2  . LEU   A 1 154 ? 40.17547 -8.88198  2.50570  1.000 67.06165  ? 151 LEU   A HB2  1 
ATOM   2337 H HB3  . LEU   A 1 154 ? 41.24806 -9.15255  1.36476  1.000 67.06165  ? 151 LEU   A HB3  1 
ATOM   2338 H HG   . LEU   A 1 154 ? 41.01565 -11.49492 2.21281  1.000 91.28426  ? 151 LEU   A HG   1 
ATOM   2339 H HD11 . LEU   A 1 154 ? 38.37727 -11.40492 2.40039  1.000 88.21339  ? 151 LEU   A HD11 1 
ATOM   2340 H HD12 . LEU   A 1 154 ? 39.37742 -11.79925 3.56988  1.000 88.21339  ? 151 LEU   A HD12 1 
ATOM   2341 H HD13 . LEU   A 1 154 ? 38.91187 -10.29020 3.39796  1.000 88.21339  ? 151 LEU   A HD13 1 
ATOM   2342 H HD21 . LEU   A 1 154 ? 39.53908 -11.94679 0.45326  1.000 76.10247  ? 151 LEU   A HD21 1 
ATOM   2343 H HD22 . LEU   A 1 154 ? 39.22981 -10.39393 0.32489  1.000 76.10247  ? 151 LEU   A HD22 1 
ATOM   2344 H HD23 . LEU   A 1 154 ? 40.67967 -10.94595 -0.01673 1.000 76.10247  ? 151 LEU   A HD23 1 
ATOM   2345 N N    . ILE   A 1 155 ? 42.39274 -10.53144 5.35386  1.000 27.05622  ? 152 ILE   A N    1 
ATOM   2346 C CA   . ILE   A 1 155 ? 42.04903 -11.04511 6.67321  1.000 29.98150  ? 152 ILE   A CA   1 
ATOM   2347 C C    . ILE   A 1 155 ? 42.91618 -10.34334 7.70491  1.000 24.03929  ? 152 ILE   A C    1 
ATOM   2348 O O    . ILE   A 1 155 ? 44.14847 -10.46356 7.68354  1.000 28.16060  ? 152 ILE   A O    1 
ATOM   2349 C CB   . ILE   A 1 155 ? 42.24242 -12.56474 6.77487  1.000 30.01212  ? 152 ILE   A CB   1 
ATOM   2350 C CG1  . ILE   A 1 155 ? 41.40370 -13.29975 5.73589  1.000 30.90030  ? 152 ILE   A CG1  1 
ATOM   2351 C CG2  . ILE   A 1 155 ? 41.90831 -13.02819 8.17940  1.000 28.08400  ? 152 ILE   A CG2  1 
ATOM   2352 C CD1  . ILE   A 1 155 ? 39.91101 -13.13810 5.89884  1.000 44.60868  ? 152 ILE   A CD1  1 
ATOM   2353 H H    . ILE   A 1 155 ? 43.17131 -10.77817 5.08450  1.000 32.48612  ? 152 ILE   A H    1 
ATOM   2354 H HA   . ILE   A 1 155 ? 41.11801 -10.83425 6.84536  1.000 35.99645  ? 152 ILE   A HA   1 
ATOM   2355 H HB   . ILE   A 1 155 ? 43.17171 -12.77119 6.58860  1.000 36.03319  ? 152 ILE   A HB   1 
ATOM   2356 H HG12 . ILE   A 1 155 ? 41.63925 -12.96446 4.85668  1.000 37.09902  ? 152 ILE   A HG12 1 
ATOM   2357 H HG13 . ILE   A 1 155 ? 41.60262 -14.24737 5.79383  1.000 37.09902  ? 152 ILE   A HG13 1 
ATOM   2358 H HG21 . ILE   A 1 155 ? 41.76424 -13.98738 8.16955  1.000 33.71946  ? 152 ILE   A HG21 1 
ATOM   2359 H HG22 . ILE   A 1 155 ? 42.64803 -12.81083 8.76801  1.000 33.71946  ? 152 ILE   A HG22 1 
ATOM   2360 H HG23 . ILE   A 1 155 ? 41.10390 -12.57593 8.47820  1.000 33.71946  ? 152 ILE   A HG23 1 
ATOM   2361 H HD11 . ILE   A 1 155 ? 39.46143 -13.62543 5.19081  1.000 53.54908  ? 152 ILE   A HD11 1 
ATOM   2362 H HD12 . ILE   A 1 155 ? 39.64750 -13.49179 6.76276  1.000 53.54908  ? 152 ILE   A HD12 1 
ATOM   2363 H HD13 . ILE   A 1 155 ? 39.68769 -12.19569 5.84515  1.000 53.54908  ? 152 ILE   A HD13 1 
ATOM   2364 N N    . LEU   A 1 156 ? 42.27665 -9.64097  8.62997  1.000 24.93565  ? 153 LEU   A N    1 
ATOM   2365 C CA   . LEU   A 1 156 ? 42.97381 -8.87723  9.65813  1.000 23.34334  ? 153 LEU   A CA   1 
ATOM   2366 C C    . LEU   A 1 156 ? 42.51438 -9.40087  11.00974 1.000 24.93885  ? 153 LEU   A C    1 
ATOM   2367 O O    . LEU   A 1 156 ? 41.31670 -9.38622  11.31040 1.000 24.19389  ? 153 LEU   A O    1 
ATOM   2368 C CB   . LEU   A 1 156 ? 42.68089 -7.38604  9.50954  1.000 22.92927  ? 153 LEU   A CB   1 
ATOM   2369 C CG   . LEU   A 1 156 ? 43.52772 -6.40548  10.31121 1.000 28.10736  ? 153 LEU   A CG   1 
ATOM   2370 C CD1  . LEU   A 1 156 ? 43.46865 -5.05134  9.64451  1.000 49.15265  ? 153 LEU   A CD1  1 
ATOM   2371 C CD2  . LEU   A 1 156 ? 43.03840 -6.30893  11.71312 1.000 31.52393  ? 153 LEU   A CD2  1 
ATOM   2372 H H    . LEU   A 1 156 ? 41.41992 -9.58966  8.68459  1.000 29.94143  ? 153 LEU   A H    1 
ATOM   2373 H HA   . LEU   A 1 156 ? 43.93358 -8.99978  9.58944  1.000 28.03066  ? 153 LEU   A HA   1 
ATOM   2374 H HB2  . LEU   A 1 156 ? 42.79781 -7.15499  8.57474  1.000 27.53377  ? 153 LEU   A HB2  1 
ATOM   2375 H HB3  . LEU   A 1 156 ? 41.75946 -7.23937  9.77479  1.000 27.53377  ? 153 LEU   A HB3  1 
ATOM   2376 H HG   . LEU   A 1 156 ? 44.44707 -6.71333  10.34163 1.000 33.74749  ? 153 LEU   A HG   1 
ATOM   2377 H HD11 . LEU   A 1 156 ? 43.94696 -4.40884  10.19162 1.000 59.00183  ? 153 LEU   A HD11 1 
ATOM   2378 H HD12 . LEU   A 1 156 ? 43.88132 -5.11222  8.76878  1.000 59.00183  ? 153 LEU   A HD12 1 
ATOM   2379 H HD13 . LEU   A 1 156 ? 42.54064 -4.78363  9.55498  1.000 59.00183  ? 153 LEU   A HD13 1 
ATOM   2380 H HD21 . LEU   A 1 156 ? 43.46918 -5.55577  12.14680 1.000 37.84737  ? 153 LEU   A HD21 1 
ATOM   2381 H HD22 . LEU   A 1 156 ? 42.07708 -6.17978  11.70388 1.000 37.84737  ? 153 LEU   A HD22 1 
ATOM   2382 H HD23 . LEU   A 1 156 ? 43.25738 -7.12977  12.18128 1.000 37.84737  ? 153 LEU   A HD23 1 
ATOM   2383 N N    . THR   A 1 157 ? 43.45767 -9.89413  11.81107 1.000 20.70527  ? 154 THR   A N    1 
ATOM   2384 C CA   . THR   A 1 157 ? 43.11931 -10.49035 13.09758 1.000 24.35368  ? 154 THR   A CA   1 
ATOM   2385 C C    . THR   A 1 157 ? 43.97857 -9.87586  14.19600 1.000 21.39564  ? 154 THR   A C    1 
ATOM   2386 O O    . THR   A 1 157 ? 45.00948 -9.24516  13.93264 1.000 21.29976  ? 154 THR   A O    1 
ATOM   2387 C CB   . THR   A 1 157 ? 43.30612 -12.02210 13.08315 1.000 22.85770  ? 154 THR   A CB   1 
ATOM   2388 O OG1  . THR   A 1 157 ? 44.60084 -12.35598 12.59033 1.000 21.03507  ? 154 THR   A OG1  1 
ATOM   2389 C CG2  . THR   A 1 157 ? 42.26622 -12.68150 12.22217 1.000 22.54247  ? 154 THR   A CG2  1 
ATOM   2390 H H    . THR   A 1 157 ? 44.29833 -9.89383  11.62972 1.000 24.86498  ? 154 THR   A H    1 
ATOM   2391 H HA   . THR   A 1 157 ? 42.19013 -10.29808 13.29897 1.000 29.24308  ? 154 THR   A HA   1 
ATOM   2392 H HB   . THR   A 1 157 ? 43.21187 -12.35574 13.98907 1.000 27.44790  ? 154 THR   A HB   1 
ATOM   2393 H HG1  . THR   A 1 157 ? 44.68352 -12.09121 11.79745 1.000 25.26074  ? 154 THR   A HG1  1 
ATOM   2394 H HG21 . THR   A 1 157 ? 42.42044 -13.63862 12.18999 1.000 27.06962  ? 154 THR   A HG21 1 
ATOM   2395 H HG22 . THR   A 1 157 ? 41.38194 -12.51715 12.58540 1.000 27.06962  ? 154 THR   A HG22 1 
ATOM   2396 H HG23 . THR   A 1 157 ? 42.30745 -12.32553 11.32079 1.000 27.06962  ? 154 THR   A HG23 1 
ATOM   2397 N N    . SER   A 1 158 ? 43.53779 -10.07300 15.43668 1.000 21.09305  ? 155 SER   A N    1 
ATOM   2398 C CA   . SER   A 1 158 ? 44.20928 -9.49215  16.59170 1.000 19.98103  ? 155 SER   A CA   1 
ATOM   2399 C C    . SER   A 1 158 ? 43.88913 -10.34300 17.81741 1.000 18.79936  ? 155 SER   A C    1 
ATOM   2400 O O    . SER   A 1 158 ? 42.95289 -11.14818 17.80520 1.000 22.91470  ? 155 SER   A O    1 
ATOM   2401 C CB   . SER   A 1 158 ? 43.78313 -8.02809  16.79265 1.000 17.10431  ? 155 SER   A CB   1 
ATOM   2402 O OG   . SER   A 1 158 ? 44.67820 -7.38560  17.67358 1.000 23.47955  ? 155 SER   A OG   1 
ATOM   2403 H H    . SER   A 1 158 ? 42.84594 -10.54348 15.63567 1.000 25.33032  ? 155 SER   A H    1 
ATOM   2404 H HA   . SER   A 1 158 ? 45.17089 -9.51094  16.46581 1.000 23.99589  ? 155 SER   A HA   1 
ATOM   2405 H HB2  . SER   A 1 158 ? 43.79378 -7.57160  15.93685 1.000 20.54382  ? 155 SER   A HB2  1 
ATOM   2406 H HB3  . SER   A 1 158 ? 42.89004 -8.00398  17.17043 1.000 20.54382  ? 155 SER   A HB3  1 
ATOM   2407 H HG   . SER   A 1 158 ? 44.68482 -7.78050  18.41494 1.000 28.19412  ? 155 SER   A HG   1 
ATOM   2408 N N    . ARG   A 1 159 ? 44.66962 -10.14680 18.87985 1.000 18.37249  ? 156 ARG   A N    1 
ATOM   2409 C CA   . ARG   A 1 159 ? 44.72572 -11.18176 19.91589 1.000 17.44078  ? 156 ARG   A CA   1 
ATOM   2410 C C    . ARG   A 1 159 ? 43.77458 -10.99567 21.09676 1.000 21.91289  ? 156 ARG   A C    1 
ATOM   2411 O O    . ARG   A 1 159 ? 43.28712 -11.98787 21.64707 1.000 22.44486  ? 156 ARG   A O    1 
ATOM   2412 C CB   . ARG   A 1 159 ? 46.16117 -11.28538 20.43568 1.000 19.63009  ? 156 ARG   A CB   1 
ATOM   2413 C CG   . ARG   A 1 159 ? 47.18616 -11.52981 19.33658 1.000 23.75694  ? 156 ARG   A CG   1 
ATOM   2414 C CD   . ARG   A 1 159 ? 48.39616 -12.24307 19.90221 1.000 22.45511  ? 156 ARG   A CD   1 
ATOM   2415 N NE   . ARG   A 1 159 ? 48.11563 -13.66250 20.06833 1.000 26.98521  ? 156 ARG   A NE   1 
ATOM   2416 C CZ   . ARG   A 1 159 ? 48.93771 -14.52618 20.63694 1.000 21.99714  ? 156 ARG   A CZ   1 
ATOM   2417 N NH1  . ARG   A 1 159 ? 50.08290 -14.13830 21.17172 1.000 35.61658  ? 156 ARG   A NH1  1 
ATOM   2418 N NH2  . ARG   A 1 159 ? 48.60797 -15.80946 20.65769 1.000 29.87017  ? 156 ARG   A NH2  1 
ATOM   2419 H H    . ARG   A 1 159 ? 45.15681 -9.45201  19.01950 1.000 22.06564  ? 156 ARG   A H    1 
ATOM   2420 H HA   . ARG   A 1 159 ? 44.45418 -12.01340 19.49693 1.000 20.94759  ? 156 ARG   A HA   1 
ATOM   2421 H HB2  . ARG   A 1 159 ? 46.39387 -10.45536 20.88045 1.000 23.57477  ? 156 ARG   A HB2  1 
ATOM   2422 H HB3  . ARG   A 1 159 ? 46.21480 -12.02389 21.06228 1.000 23.57477  ? 156 ARG   A HB3  1 
ATOM   2423 H HG2  . ARG   A 1 159 ? 46.79525 -12.08365 18.64279 1.000 28.52698  ? 156 ARG   A HG2  1 
ATOM   2424 H HG3  . ARG   A 1 159 ? 47.47219 -10.68185 18.96234 1.000 28.52698  ? 156 ARG   A HG3  1 
ATOM   2425 H HD2  . ARG   A 1 159 ? 49.14571 -12.14438 19.29449 1.000 26.96479  ? 156 ARG   A HD2  1 
ATOM   2426 H HD3  . ARG   A 1 159 ? 48.61969 -11.86793 20.76836 1.000 26.96479  ? 156 ARG   A HD3  1 
ATOM   2427 H HE   . ARG   A 1 159 ? 47.36301 -13.95879 19.77615 1.000 32.40091  ? 156 ARG   A HE   1 
ATOM   2428 H HH11 . ARG   A 1 159 ? 50.30636 -13.30803 21.15404 1.000 42.75856  ? 156 ARG   A HH11 1 
ATOM   2429 H HH12 . ARG   A 1 159 ? 50.60436 -14.71627 21.53728 1.000 42.75856  ? 156 ARG   A HH12 1 
ATOM   2430 H HH21 . ARG   A 1 159 ? 47.86817 -16.06911 20.30431 1.000 35.86286  ? 156 ARG   A HH21 1 
ATOM   2431 H HH22 . ARG   A 1 159 ? 49.13377 -16.38266 21.02455 1.000 35.86286  ? 156 ARG   A HH22 1 
ATOM   2432 N N    . GLY   A 1 160 ? 43.50047 -9.78003  21.54082 1.000 25.71786  ? 157 GLY   A N    1 
ATOM   2433 C CA   . GLY   A 1 160 ? 42.75642 -9.65436  22.77122 1.000 20.50033  ? 157 GLY   A CA   1 
ATOM   2434 C C    . GLY   A 1 160 ? 42.25200 -8.26941  23.08504 1.000 18.79779  ? 157 GLY   A C    1 
ATOM   2435 O O    . GLY   A 1 160 ? 42.42173 -7.32802  22.31025 1.000 20.79789  ? 157 GLY   A O    1 
ATOM   2436 H H    . GLY   A 1 160 ? 43.72759 -9.04361  21.15912 1.000 30.88008  ? 157 GLY   A H    1 
ATOM   2437 H HA2  . GLY   A 1 160 ? 41.98667 -10.24304 22.72833 1.000 24.61905  ? 157 GLY   A HA2  1 
ATOM   2438 H HA3  . GLY   A 1 160 ? 43.32551 -9.93167  23.50616 1.000 24.61905  ? 157 GLY   A HA3  1 
ATOM   2439 N N    . PRO   A 1 161 ? 41.58596 -8.12904  24.23596 1.000 20.41370  ? 158 PRO   A N    1 
ATOM   2440 C CA   . PRO   A 1 161 ? 41.04978 -6.80678  24.59137 1.000 18.04023  ? 158 PRO   A CA   1 
ATOM   2441 C C    . PRO   A 1 161 ? 42.12618 -5.74830  24.60354 1.000 21.12756  ? 158 PRO   A C    1 
ATOM   2442 O O    . PRO   A 1 161 ? 41.89283 -4.63211  24.12578 1.000 20.32334  ? 158 PRO   A O    1 
ATOM   2443 C CB   . PRO   A 1 161 ? 40.43772 -7.04087  25.98356 1.000 31.77915  ? 158 PRO   A CB   1 
ATOM   2444 C CG   . PRO   A 1 161 ? 40.07781 -8.48797  25.99863 1.000 24.59194  ? 158 PRO   A CG   1 
ATOM   2445 C CD   . PRO   A 1 161 ? 41.18482 -9.17118  25.20883 1.000 19.51655  ? 158 PRO   A CD   1 
ATOM   2446 H HA   . PRO   A 1 161 ? 40.33967 -6.54534  23.98451 1.000 21.66693  ? 158 PRO   A HA   1 
ATOM   2447 H HB2  . PRO   A 1 161 ? 41.09061 -6.83703  26.67136 1.000 38.15363  ? 158 PRO   A HB2  1 
ATOM   2448 H HB3  . PRO   A 1 161 ? 39.65105 -6.48497  26.09767 1.000 38.15363  ? 158 PRO   A HB3  1 
ATOM   2449 H HG2  . PRO   A 1 161 ? 40.05083 -8.81345  26.91200 1.000 29.52898  ? 158 PRO   A HG2  1 
ATOM   2450 H HG3  . PRO   A 1 161 ? 39.21574 -8.61969  25.57390 1.000 29.52898  ? 158 PRO   A HG3  1 
ATOM   2451 H HD2  . PRO   A 1 161 ? 41.92637 -9.41044  25.78655 1.000 23.43852  ? 158 PRO   A HD2  1 
ATOM   2452 H HD3  . PRO   A 1 161 ? 40.85055 -9.96012  24.75414 1.000 23.43852  ? 158 PRO   A HD3  1 
ATOM   2453 N N    . GLY   A 1 162 ? 43.32404 -6.09763  25.07868 1.000 25.28350  ? 159 GLY   A N    1 
ATOM   2454 C CA   . GLY   A 1 162 ? 44.44840 -5.18059  25.14237 1.000 25.65992  ? 159 GLY   A CA   1 
ATOM   2455 C C    . GLY   A 1 162 ? 45.09274 -4.86166  23.81400 1.000 21.94309  ? 159 GLY   A C    1 
ATOM   2456 O O    . GLY   A 1 162 ? 45.95206 -3.97685  23.76819 1.000 23.68557  ? 159 GLY   A O    1 
ATOM   2457 H H    . GLY   A 1 162 ? 43.51062 -6.88237  25.37697 1.000 30.35885  ? 159 GLY   A H    1 
ATOM   2458 H HA2  . GLY   A 1 162 ? 44.14481 -4.34506  25.53046 1.000 30.81055  ? 159 GLY   A HA2  1 
ATOM   2459 H HA3  . GLY   A 1 162 ? 45.12989 -5.56568  25.71523 1.000 30.81055  ? 159 GLY   A HA3  1 
ATOM   2460 N N    . THR   A 1 163 ? 44.70770 -5.54011  22.73667 1.000 20.87863  ? 160 THR   A N    1 
ATOM   2461 C CA   . THR   A 1 163 ? 45.17692 -5.18011  21.40890 1.000 22.44623  ? 160 THR   A CA   1 
ATOM   2462 C C    . THR   A 1 163 ? 44.11005 -4.43388  20.61775 1.000 22.20217  ? 160 THR   A C    1 
ATOM   2463 O O    . THR   A 1 163 ? 44.31571 -4.13429  19.43523 1.000 19.12258  ? 160 THR   A O    1 
ATOM   2464 C CB   . THR   A 1 163 ? 45.64232 -6.41738  20.62781 1.000 22.24141  ? 160 THR   A CB   1 
ATOM   2465 O OG1  . THR   A 1 163 ? 44.54651 -7.28345  20.33527 1.000 20.76940  ? 160 THR   A OG1  1 
ATOM   2466 C CG2  . THR   A 1 163 ? 46.69115 -7.19791  21.42491 1.000 30.07707  ? 160 THR   A CG2  1 
ATOM   2467 H H    . THR   A 1 163 ? 44.17370 -6.21404  22.75290 1.000 25.07301  ? 160 THR   A H    1 
ATOM   2468 H HA   . THR   A 1 163 ? 45.95201 -4.60495  21.50547 1.000 26.95413  ? 160 THR   A HA   1 
ATOM   2469 H HB   . THR   A 1 163 ? 46.03541 -6.11783  19.79315 1.000 26.70834  ? 160 THR   A HB   1 
ATOM   2470 H HG1  . THR   A 1 163 ? 43.96198 -6.86913  19.89679 1.000 24.94193  ? 160 THR   A HG1  1 
ATOM   2471 H HG21 . THR   A 1 163 ? 47.00855 -7.95295  20.90523 1.000 36.11114  ? 160 THR   A HG21 1 
ATOM   2472 H HG22 . THR   A 1 163 ? 47.44312 -6.62269  21.63602 1.000 36.11114  ? 160 THR   A HG22 1 
ATOM   2473 H HG23 . THR   A 1 163 ? 46.30351 -7.52541  22.25157 1.000 36.11114  ? 160 THR   A HG23 1 
ATOM   2474 N N    . SER   A 1 164 ? 42.99371 -4.09046  21.26360 1.000 17.60950  ? 161 SER   A N    1 
ATOM   2475 C CA   . SER   A 1 164 ? 41.85176 -3.53583  20.55288 1.000 19.29078  ? 161 SER   A CA   1 
ATOM   2476 C C    . SER   A 1 164 ? 42.19302 -2.22109  19.86776 1.000 23.44313  ? 161 SER   A C    1 
ATOM   2477 O O    . SER   A 1 164 ? 41.70267 -1.95241  18.76939 1.000 23.14088  ? 161 SER   A O    1 
ATOM   2478 C CB   . SER   A 1 164 ? 40.68522 -3.32451  21.51368 1.000 23.36412  ? 161 SER   A CB   1 
ATOM   2479 O OG   . SER   A 1 164 ? 40.07620 -4.55111  21.84221 1.000 31.95766  ? 161 SER   A OG   1 
ATOM   2480 H H    . SER   A 1 164 ? 42.87555 -4.16972  22.11175 1.000 21.15005  ? 161 SER   A H    1 
ATOM   2481 H HA   . SER   A 1 164 ? 41.58616 -4.17364  19.87203 1.000 23.16759  ? 161 SER   A HA   1 
ATOM   2482 H HB2  . SER   A 1 164 ? 41.01627 -2.90924  22.32538 1.000 28.05560  ? 161 SER   A HB2  1 
ATOM   2483 H HB3  . SER   A 1 164 ? 40.02843 -2.74940  21.09086 1.000 28.05560  ? 161 SER   A HB3  1 
ATOM   2484 H HG   . SER   A 1 164 ? 39.45156 -4.42429  22.38934 1.000 38.36784  ? 161 SER   A HG   1 
ATOM   2485 N N    . PHE   A 1 165 ? 43.01546 -1.37769  20.50287 1.000 18.04846  ? 162 PHE   A N    1 
ATOM   2486 C CA   . PHE   A 1 165 ? 43.35021 -0.10179  19.87989 1.000 22.95229  ? 162 PHE   A CA   1 
ATOM   2487 C C    . PHE   A 1 165 ? 44.19901 -0.30899  18.63677 1.000 16.55258  ? 162 PHE   A C    1 
ATOM   2488 O O    . PHE   A 1 165 ? 43.96944 0.32636   17.60562 1.000 23.19249  ? 162 PHE   A O    1 
ATOM   2489 C CB   . PHE   A 1 165 ? 44.08706 0.80995   20.85623 1.000 24.10708  ? 162 PHE   A CB   1 
ATOM   2490 C CG   . PHE   A 1 165 ? 43.18976 1.47601   21.86736 1.000 28.30656  ? 162 PHE   A CG   1 
ATOM   2491 C CD1  . PHE   A 1 165 ? 42.37996 2.54099   21.49788 1.000 20.05160  ? 162 PHE   A CD1  1 
ATOM   2492 C CD2  . PHE   A 1 165 ? 43.18096 1.05559   23.18570 1.000 26.85083  ? 162 PHE   A CD2  1 
ATOM   2493 C CE1  . PHE   A 1 165 ? 41.56565 3.16754   22.43692 1.000 30.81228  ? 162 PHE   A CE1  1 
ATOM   2494 C CE2  . PHE   A 1 165 ? 42.36900 1.67116   24.11887 1.000 33.21298  ? 162 PHE   A CE2  1 
ATOM   2495 C CZ   . PHE   A 1 165 ? 41.55694 2.72746   23.74282 1.000 29.17493  ? 162 PHE   A CZ   1 
ATOM   2496 H H    . PHE   A 1 165 ? 43.37885 -1.51913  21.26938 1.000 21.67681  ? 162 PHE   A H    1 
ATOM   2497 H HA   . PHE   A 1 165 ? 42.51950 0.33307   19.63143 1.000 27.56140  ? 162 PHE   A HA   1 
ATOM   2498 H HB2  . PHE   A 1 165 ? 44.73948 0.28224   21.34280 1.000 28.94715  ? 162 PHE   A HB2  1 
ATOM   2499 H HB3  . PHE   A 1 165 ? 44.53408 1.50832   20.35288 1.000 28.94715  ? 162 PHE   A HB3  1 
ATOM   2500 H HD1  . PHE   A 1 165 ? 42.38145 2.83808   20.61661 1.000 24.08057  ? 162 PHE   A HD1  1 
ATOM   2501 H HD2  . PHE   A 1 165 ? 43.72808 0.35030   23.44671 1.000 32.23965  ? 162 PHE   A HD2  1 
ATOM   2502 H HE1  . PHE   A 1 165 ? 41.02785 3.88261   22.18324 1.000 36.99339  ? 162 PHE   A HE1  1 
ATOM   2503 H HE2  . PHE   A 1 165 ? 42.36799 1.37557   25.00065 1.000 39.87423  ? 162 PHE   A HE2  1 
ATOM   2504 H HZ   . PHE   A 1 165 ? 41.00701 3.13896   24.36984 1.000 35.02857  ? 162 PHE   A HZ   1 
ATOM   2505 N N    . GLU   A 1 166 ? 45.21920 -1.16129  18.73099 1.000 19.07492  ? 163 GLU   A N    1 
ATOM   2506 C CA   . GLU   A 1 166 ? 46.05067 -1.44782  17.56751 1.000 22.00831  ? 163 GLU   A CA   1 
ATOM   2507 C C    . GLU   A 1 166 ? 45.21578 -2.06959  16.45775 1.000 23.32331  ? 163 GLU   A C    1 
ATOM   2508 O O    . GLU   A 1 166 ? 45.35269 -1.71282  15.28113 1.000 24.12769  ? 163 GLU   A O    1 
ATOM   2509 C CB   . GLU   A 1 166 ? 47.20173 -2.36093  17.97657 1.000 22.72329  ? 163 GLU   A CB   1 
ATOM   2510 C CG   . GLU   A 1 166 ? 48.10626 -1.74033  19.01447 1.000 33.23523  ? 163 GLU   A CG   1 
ATOM   2511 C CD   . GLU   A 1 166 ? 48.64938 -2.75085  19.99709 1.000 46.32553  ? 163 GLU   A CD   1 
ATOM   2512 O OE1  . GLU   A 1 166 ? 49.61616 -3.46815  19.65162 1.000 36.21724  ? 163 GLU   A OE1  1 
ATOM   2513 O OE2  . GLU   A 1 166 ? 48.09449 -2.83525  21.11157 1.000 55.35903  ? 163 GLU   A OE2  1 
ATOM   2514 H H    . GLU   A 1 166 ? 45.44705 -1.58022  19.44666 1.000 22.90855  ? 163 GLU   A H    1 
ATOM   2515 H HA   . GLU   A 1 166 ? 46.43597 -0.62640  17.22440 1.000 26.42863  ? 163 GLU   A HA   1 
ATOM   2516 H HB2  . GLU   A 1 166 ? 46.83742 -3.17965  18.34789 1.000 27.28661  ? 163 GLU   A HB2  1 
ATOM   2517 H HB3  . GLU   A 1 166 ? 47.73793 -2.56160  17.19354 1.000 27.28661  ? 163 GLU   A HB3  1 
ATOM   2518 H HG2  . GLU   A 1 166 ? 48.85890 -1.32187  18.56802 1.000 39.90094  ? 163 GLU   A HG2  1 
ATOM   2519 H HG3  . GLU   A 1 166 ? 47.60545 -1.07619  19.51349 1.000 39.90094  ? 163 GLU   A HG3  1 
ATOM   2520 N N    . PHE   A 1 167 ? 44.31813 -2.97604  16.82593 1.000 16.92483  ? 164 PHE   A N    1 
ATOM   2521 C CA   . PHE   A 1 167 ? 43.39448 -3.58308  15.87162 1.000 20.73379  ? 164 PHE   A CA   1 
ATOM   2522 C C    . PHE   A 1 167 ? 42.55983 -2.52980  15.15801 1.000 28.25327  ? 164 PHE   A C    1 
ATOM   2523 O O    . PHE   A 1 167 ? 42.48473 -2.51851  13.92339 1.000 20.03927  ? 164 PHE   A O    1 
ATOM   2524 C CB   . PHE   A 1 167 ? 42.53315 -4.57561  16.64983 1.000 25.07760  ? 164 PHE   A CB   1 
ATOM   2525 C CG   . PHE   A 1 167 ? 41.42137 -5.20634  15.87765 1.000 22.14543  ? 164 PHE   A CG   1 
ATOM   2526 C CD1  . PHE   A 1 167 ? 41.67763 -6.13107  14.88673 1.000 26.41523  ? 164 PHE   A CD1  1 
ATOM   2527 C CD2  . PHE   A 1 167 ? 40.09954 -4.94661  16.21664 1.000 20.52057  ? 164 PHE   A CD2  1 
ATOM   2528 C CE1  . PHE   A 1 167 ? 40.64655 -6.74278  14.19874 1.000 20.36786  ? 164 PHE   A CE1  1 
ATOM   2529 C CE2  . PHE   A 1 167 ? 39.05902 -5.56210  15.54417 1.000 22.02582  ? 164 PHE   A CE2  1 
ATOM   2530 C CZ   . PHE   A 1 167 ? 39.33515 -6.47430  14.53519 1.000 21.76296  ? 164 PHE   A CZ   1 
ATOM   2531 H H    . PHE   A 1 167 ? 44.22005 -3.26192  17.63108 1.000 20.32845  ? 164 PHE   A H    1 
ATOM   2532 H HA   . PHE   A 1 167 ? 43.87389 -4.05642  15.17376 1.000 24.89921  ? 164 PHE   A HA   1 
ATOM   2533 H HB2  . PHE   A 1 167 ? 43.10507 -5.29119  16.96880 1.000 30.11178  ? 164 PHE   A HB2  1 
ATOM   2534 H HB3  . PHE   A 1 167 ? 42.13435 -4.10966  17.40133 1.000 30.11178  ? 164 PHE   A HB3  1 
ATOM   2535 H HD1  . PHE   A 1 167 ? 42.55801 -6.34636  14.67823 1.000 31.71693  ? 164 PHE   A HD1  1 
ATOM   2536 H HD2  . PHE   A 1 167 ? 39.91145 -4.35060  16.90533 1.000 24.64333  ? 164 PHE   A HD2  1 
ATOM   2537 H HE1  . PHE   A 1 167 ? 40.83670 -7.33603  13.50824 1.000 24.46008  ? 164 PHE   A HE1  1 
ATOM   2538 H HE2  . PHE   A 1 167 ? 38.17787 -5.36541  15.76730 1.000 26.44964  ? 164 PHE   A HE2  1 
ATOM   2539 H HZ   . PHE   A 1 167 ? 38.64066 -6.90210  14.08847 1.000 26.13420  ? 164 PHE   A HZ   1 
ATOM   2540 N N    . ALA   A 1 168 ? 41.93815 -1.61976  15.91751 1.000 22.71692  ? 165 ALA   A N    1 
ATOM   2541 C CA   . ALA   A 1 168 ? 41.06311 -0.61336  15.31311 1.000 23.30449  ? 165 ALA   A CA   1 
ATOM   2542 C C    . ALA   A 1 168 ? 41.83558 0.33015   14.40139 1.000 20.34106  ? 165 ALA   A C    1 
ATOM   2543 O O    . ALA   A 1 168 ? 41.36439 0.67836   13.30984 1.000 20.58674  ? 165 ALA   A O    1 
ATOM   2544 C CB   . ALA   A 1 168 ? 40.34406 0.17835   16.40780 1.000 21.43722  ? 165 ALA   A CB   1 
ATOM   2545 H H    . ALA   A 1 168 ? 42.00585 -1.56495  16.77309 1.000 27.27896  ? 165 ALA   A H    1 
ATOM   2546 H HA   . ALA   A 1 168 ? 40.39741 -1.06924  14.77467 1.000 27.98404  ? 165 ALA   A HA   1 
ATOM   2547 H HB1  . ALA   A 1 168 ? 39.75927 0.83155   15.99276 1.000 25.74332  ? 165 ALA   A HB1  1 
ATOM   2548 H HB2  . ALA   A 1 168 ? 39.82332 -0.43432  16.95035 1.000 25.74332  ? 165 ALA   A HB2  1 
ATOM   2549 H HB3  . ALA   A 1 168 ? 41.00446 0.62793   16.95794 1.000 25.74332  ? 165 ALA   A HB3  1 
ATOM   2550 N N    . LEU   A 1 169 ? 43.02987 0.75541   14.82829 1.000 20.83871  ? 166 LEU   A N    1 
ATOM   2551 C CA   . LEU   A 1 169 ? 43.82739 1.65768   14.00377 1.000 25.39526  ? 166 LEU   A CA   1 
ATOM   2552 C C    . LEU   A 1 169 ? 44.35648 0.97437   12.74528 1.000 26.83869  ? 166 LEU   A C    1 
ATOM   2553 O O    . LEU   A 1 169 ? 44.59742 1.64637   11.73573 1.000 21.86198  ? 166 LEU   A O    1 
ATOM   2554 C CB   . LEU   A 1 169 ? 44.98142 2.22454   14.83050 1.000 23.34756  ? 166 LEU   A CB   1 
ATOM   2555 C CG   . LEU   A 1 169 ? 44.59406 3.25529   15.90098 1.000 25.57364  ? 166 LEU   A CG   1 
ATOM   2556 C CD1  . LEU   A 1 169 ? 45.76379 3.57439   16.80220 1.000 25.27187  ? 166 LEU   A CD1  1 
ATOM   2557 C CD2  . LEU   A 1 169 ? 44.06882 4.52325   15.23348 1.000 36.07782  ? 166 LEU   A CD2  1 
ATOM   2558 H H    . LEU   A 1 169 ? 43.39177 0.53874   15.57775 1.000 25.02510  ? 166 LEU   A H    1 
ATOM   2559 H HA   . LEU   A 1 169 ? 43.26557 2.39454   13.71691 1.000 30.49296  ? 166 LEU   A HA   1 
ATOM   2560 H HB2  . LEU   A 1 169 ? 45.41912 1.48787   15.28507 1.000 28.03572  ? 166 LEU   A HB2  1 
ATOM   2561 H HB3  . LEU   A 1 169 ? 45.60363 2.65770   14.22542 1.000 28.03572  ? 166 LEU   A HB3  1 
ATOM   2562 H HG   . LEU   A 1 169 ? 43.89322 2.88281   16.45863 1.000 30.70702  ? 166 LEU   A HG   1 
ATOM   2563 H HD11 . LEU   A 1 169 ? 45.49105 4.24450   17.44831 1.000 30.34489  ? 166 LEU   A HD11 1 
ATOM   2564 H HD12 . LEU   A 1 169 ? 46.03894 2.76523   17.26096 1.000 30.34489  ? 166 LEU   A HD12 1 
ATOM   2565 H HD13 . LEU   A 1 169 ? 46.49495 3.91354   16.26249 1.000 30.34489  ? 166 LEU   A HD13 1 
ATOM   2566 H HD21 . LEU   A 1 169 ? 44.02290 5.23209   15.89404 1.000 43.31204  ? 166 LEU   A HD21 1 
ATOM   2567 H HD22 . LEU   A 1 169 ? 44.67252 4.77667   14.51778 1.000 43.31204  ? 166 LEU   A HD22 1 
ATOM   2568 H HD23 . LEU   A 1 169 ? 43.18498 4.34812   14.87424 1.000 43.31204  ? 166 LEU   A HD23 1 
ATOM   2569 N N    . ALA   A 1 170 ? 44.54783 -0.34351  12.78354 1.000 22.35591  ? 167 ALA   A N    1 
ATOM   2570 C CA   . ALA   A 1 170 ? 44.91885 -1.07224  11.57214 1.000 21.04118  ? 167 ALA   A CA   1 
ATOM   2571 C C    . ALA   A 1 170 ? 43.78384 -1.05440  10.55551 1.000 20.54893  ? 167 ALA   A C    1 
ATOM   2572 O O    . ALA   A 1 170 ? 44.02340 -0.96323  9.35025  1.000 26.32212  ? 167 ALA   A O    1 
ATOM   2573 C CB   . ALA   A 1 170 ? 45.30124 -2.51114  11.92366 1.000 30.50912  ? 167 ALA   A CB   1 
ATOM   2574 H H    . ALA   A 1 170 ? 44.47058 -0.83254  13.48673 1.000 26.84574  ? 167 ALA   A H    1 
ATOM   2575 H HA   . ALA   A 1 170 ? 45.69227 -0.64544  11.17142 1.000 25.26807  ? 167 ALA   A HA   1 
ATOM   2576 H HB1  . ALA   A 1 170 ? 45.56314 -2.97529  11.11318 1.000 36.62960  ? 167 ALA   A HB1  1 
ATOM   2577 H HB2  . ALA   A 1 170 ? 46.04125 -2.49707  12.55062 1.000 36.62960  ? 167 ALA   A HB2  1 
ATOM   2578 H HB3  . ALA   A 1 170 ? 44.53613 -2.95220  12.32488 1.000 36.62960  ? 167 ALA   A HB3  1 
ATOM   2579 N N    . ILE   A 1 171 ? 42.54246 -1.16653  11.02702 1.000 22.66569  ? 168 ILE   A N    1 
ATOM   2580 C CA   . ILE   A 1 171 ? 41.39234 -1.03068  10.14607 1.000 22.60586  ? 168 ILE   A CA   1 
ATOM   2581 C C    . ILE   A 1 171 ? 41.38123 0.35816   9.51503  1.000 22.87074  ? 168 ILE   A C    1 
ATOM   2582 O O    . ILE   A 1 171 ? 41.21901 0.50531   8.29550  1.000 24.89354  ? 168 ILE   A O    1 
ATOM   2583 C CB   . ILE   A 1 171 ? 40.08884 -1.30664  10.91765 1.000 25.65900  ? 168 ILE   A CB   1 
ATOM   2584 C CG1  . ILE   A 1 171 ? 40.05740 -2.74352  11.43800 1.000 22.21113  ? 168 ILE   A CG1  1 
ATOM   2585 C CG2  . ILE   A 1 171 ? 38.88902 -1.02343  10.03359 1.000 27.49500  ? 168 ILE   A CG2  1 
ATOM   2586 C CD1  . ILE   A 1 171 ? 38.93382 -3.01251  12.42869 1.000 25.04849  ? 168 ILE   A CD1  1 
ATOM   2587 H H    . ILE   A 1 171 ? 42.34286 -1.32035  11.84927 1.000 27.21748  ? 168 ILE   A H    1 
ATOM   2588 H HA   . ILE   A 1 171 ? 41.46449 -1.68768  9.43610  1.000 27.14569  ? 168 ILE   A HA   1 
ATOM   2589 H HB   . ILE   A 1 171 ? 40.05569 -0.71373  11.68463 1.000 30.80946  ? 168 ILE   A HB   1 
ATOM   2590 H HG12 . ILE   A 1 171 ? 39.93945 -3.34495  10.68616 1.000 26.67202  ? 168 ILE   A HG12 1 
ATOM   2591 H HG13 . ILE   A 1 171 ? 40.89748 -2.93182  11.88488 1.000 26.67202  ? 168 ILE   A HG13 1 
ATOM   2592 H HG21 . ILE   A 1 171 ? 38.08839 -1.34885  10.47404 1.000 33.01266  ? 168 ILE   A HG21 1 
ATOM   2593 H HG22 . ILE   A 1 171 ? 38.82166 -0.06654  9.88965  1.000 33.01266  ? 168 ILE   A HG22 1 
ATOM   2594 H HG23 . ILE   A 1 171 ? 39.00771 -1.47804  9.18498  1.000 33.01266  ? 168 ILE   A HG23 1 
ATOM   2595 H HD11 . ILE   A 1 171 ? 39.09795 -3.86075  12.86967 1.000 30.07684  ? 168 ILE   A HD11 1 
ATOM   2596 H HD12 . ILE   A 1 171 ? 38.91272 -2.29766  13.08400 1.000 30.07684  ? 168 ILE   A HD12 1 
ATOM   2597 H HD13 . ILE   A 1 171 ? 38.09136 -3.04659  11.94911 1.000 30.07684  ? 168 ILE   A HD13 1 
ATOM   2598 N N    . VAL   A 1 172 ? 41.56663 1.39923   10.33500 1.000 25.42484  ? 169 VAL   A N    1 
ATOM   2599 C CA   . VAL   A 1 172 ? 41.55428 2.76544   9.80771  1.000 21.23506  ? 169 VAL   A CA   1 
ATOM   2600 C C    . VAL   A 1 172 ? 42.63720 2.93024   8.74719  1.000 29.52344  ? 169 VAL   A C    1 
ATOM   2601 O O    . VAL   A 1 172 ? 42.40227 3.48783   7.67053  1.000 25.84791  ? 169 VAL   A O    1 
ATOM   2602 C CB   . VAL   A 1 172 ? 41.73036 3.78136   10.95099 1.000 22.46900  ? 169 VAL   A CB   1 
ATOM   2603 C CG1  . VAL   A 1 172 ? 41.89302 5.21212   10.40759 1.000 25.09745  ? 169 VAL   A CG1  1 
ATOM   2604 C CG2  . VAL   A 1 172 ? 40.54833 3.70354   11.90455 1.000 20.86765  ? 169 VAL   A CG2  1 
ATOM   2605 H H    . VAL   A 1 172 ? 41.69881 1.34173   11.18283 1.000 30.52846  ? 169 VAL   A H    1 
ATOM   2606 H HA   . VAL   A 1 172 ? 40.69456 2.92811   9.38898  1.000 25.50073  ? 169 VAL   A HA   1 
ATOM   2607 H HB   . VAL   A 1 172 ? 42.53968 3.56117   11.43825 1.000 26.98145  ? 169 VAL   A HB   1 
ATOM   2608 H HG11 . VAL   A 1 172 ? 41.75933 5.84242   11.13268 1.000 30.13559  ? 169 VAL   A HG11 1 
ATOM   2609 H HG12 . VAL   A 1 172 ? 42.78639 5.31185   10.04312 1.000 30.13559  ? 169 VAL   A HG12 1 
ATOM   2610 H HG13 . VAL   A 1 172 ? 41.23346 5.36282   9.71249  1.000 30.13559  ? 169 VAL   A HG13 1 
ATOM   2611 H HG21 . VAL   A 1 172 ? 40.69642 4.31632   12.64175 1.000 25.05983  ? 169 VAL   A HG21 1 
ATOM   2612 H HG22 . VAL   A 1 172 ? 39.74065 3.94958   11.42705 1.000 25.05983  ? 169 VAL   A HG22 1 
ATOM   2613 H HG23 . VAL   A 1 172 ? 40.47152 2.79624   12.23892 1.000 25.05983  ? 169 VAL   A HG23 1 
ATOM   2614 N N    . GLU   A 1 173 ? 43.84189 2.43863   9.03762  1.000 24.80476  ? 170 GLU   A N    1 
ATOM   2615 C CA   . GLU   A 1 173 ? 44.94453 2.55972   8.08934  1.000 30.61593  ? 170 GLU   A CA   1 
ATOM   2616 C C    . GLU   A 1 173 ? 44.63058 1.84115   6.78135  1.000 34.46531  ? 170 GLU   A C    1 
ATOM   2617 O O    . GLU   A 1 173 ? 44.92081 2.35797   5.70064  1.000 29.19468  ? 170 GLU   A O    1 
ATOM   2618 C CB   . GLU   A 1 173 ? 46.22422 2.02078   8.73722  1.000 28.89774  ? 170 GLU   A CB   1 
ATOM   2619 C CG   . GLU   A 1 173 ? 47.47066 2.13837   7.88858  1.000 55.44323  ? 170 GLU   A CG   1 
ATOM   2620 C CD   . GLU   A 1 173 ? 48.73001 1.78052   8.65085  1.000 61.00853  ? 170 GLU   A CD   1 
ATOM   2621 O OE1  . GLU   A 1 173 ? 48.76208 1.99531   9.88311  1.000 66.85143  ? 170 GLU   A OE1  1 
ATOM   2622 O OE2  . GLU   A 1 173 ? 49.68405 1.28803   8.01021  1.000 65.24070  ? 170 GLU   A OE2  1 
ATOM   2623 H H    . GLU   A 1 173 ? 44.04440 2.03477   9.76939  1.000 29.78436  ? 170 GLU   A H    1 
ATOM   2624 H HA   . GLU   A 1 173 ? 45.08960 3.49361   7.87091  1.000 36.75777  ? 170 GLU   A HA   1 
ATOM   2625 H HB2  . GLU   A 1 173 ? 46.38365 2.51340   9.55746  1.000 34.69594  ? 170 GLU   A HB2  1 
ATOM   2626 H HB3  . GLU   A 1 173 ? 46.09509 1.07998   8.93502  1.000 34.69594  ? 170 GLU   A HB3  1 
ATOM   2627 H HG2  . GLU   A 1 173 ? 47.39629 1.53650   7.13153  1.000 66.55053  ? 170 GLU   A HG2  1 
ATOM   2628 H HG3  . GLU   A 1 173 ? 47.55709 3.05318   7.57787  1.000 66.55053  ? 170 GLU   A HG3  1 
ATOM   2629 N N    . ALA   A 1 174 ? 44.00209 0.66664   6.85918  1.000 26.00622  ? 171 ALA   A N    1 
ATOM   2630 C CA   . ALA   A 1 174 ? 43.66123 -0.08773  5.66079  1.000 26.47212  ? 171 ALA   A CA   1 
ATOM   2631 C C    . ALA   A 1 174 ? 42.60558 0.61699   4.82548  1.000 31.39251  ? 171 ALA   A C    1 
ATOM   2632 O O    . ALA   A 1 174 ? 42.61135 0.51500   3.59573  1.000 35.05105  ? 171 ALA   A O    1 
ATOM   2633 C CB   . ALA   A 1 174 ? 43.14525 -1.47364  6.04450  1.000 23.18956  ? 171 ALA   A CB   1 
ATOM   2634 H H    A ALA   A 1 174 ? 43.76355 0.28751   7.59332  0.530 31.22611  ? 171 ALA   A H    1 
ATOM   2635 H H    B ALA   A 1 174 ? 43.76355 0.28751   7.59332  0.470 31.22611  ? 171 ALA   A H    1 
ATOM   2636 H HA   . ALA   A 1 174 ? 44.46767 -0.17822  5.12941  1.000 31.78519  ? 171 ALA   A HA   1 
ATOM   2637 H HB1  . ALA   A 1 174 ? 42.93154 -1.96592  5.23649  1.000 27.84612  ? 171 ALA   A HB1  1 
ATOM   2638 H HB2  . ALA   A 1 174 ? 43.83397 -1.94001  6.54357  1.000 27.84612  ? 171 ALA   A HB2  1 
ATOM   2639 H HB3  . ALA   A 1 174 ? 42.35029 -1.37440  6.59139  1.000 27.84612  ? 171 ALA   A HB3  1 
ATOM   2640 N N    . LEU   A 1 175 ? 41.65540 1.28441   5.47837  1.000 32.59444  ? 172 LEU   A N    1 
ATOM   2641 C CA   . LEU   A 1 175 ? 40.55704 1.94468   4.78977  1.000 29.99915  ? 172 LEU   A CA   1 
ATOM   2642 C C    . LEU   A 1 175 ? 40.91137 3.36732   4.37866  1.000 34.63405  ? 172 LEU   A C    1 
ATOM   2643 O O    . LEU   A 1 175 ? 40.66403 3.76577   3.23734  1.000 33.67877  ? 172 LEU   A O    1 
ATOM   2644 C CB   . LEU   A 1 175 ? 39.31986 1.96875   5.68948  1.000 27.52828  ? 172 LEU   A CB   1 
ATOM   2645 C CG   . LEU   A 1 175 ? 38.30267 0.85003   5.48310  1.000 37.63912  ? 172 LEU   A CG   1 
ATOM   2646 C CD1  . LEU   A 1 175 ? 39.03280 -0.44073  5.35174  1.000 36.31005  ? 172 LEU   A CD1  1 
ATOM   2647 C CD2  . LEU   A 1 175 ? 37.29398 0.78109   6.61402  1.000 37.30324  ? 172 LEU   A CD2  1 
ATOM   2648 H H    . LEU   A 1 175 ? 41.62705 1.36875   6.33376  1.000 39.13199  ? 172 LEU   A H    1 
ATOM   2649 H HA   . LEU   A 1 175 ? 40.35015 1.43872   3.98846  1.000 36.01763  ? 172 LEU   A HA   1 
ATOM   2650 H HB2  . LEU   A 1 175 ? 39.61801 1.91581   6.61100  1.000 33.05259  ? 172 LEU   A HB2  1 
ATOM   2651 H HB3  . LEU   A 1 175 ? 38.85551 2.80693   5.53866  1.000 33.05259  ? 172 LEU   A HB3  1 
ATOM   2652 H HG   . LEU   A 1 175 ? 37.79507 1.02495   4.67523  1.000 45.18559  ? 172 LEU   A HG   1 
ATOM   2653 H HD11 . LEU   A 1 175 ? 38.41084 -1.17130  5.49435  1.000 43.59071  ? 172 LEU   A HD11 1 
ATOM   2654 H HD12 . LEU   A 1 175 ? 39.41319 -0.49919  4.46135  1.000 43.59071  ? 172 LEU   A HD12 1 
ATOM   2655 H HD13 . LEU   A 1 175 ? 39.73900 -0.47310  6.01592  1.000 43.59071  ? 172 LEU   A HD13 1 
ATOM   2656 H HD21 . LEU   A 1 175 ? 36.62745 0.10896   6.40216  1.000 44.78254  ? 172 LEU   A HD21 1 
ATOM   2657 H HD22 . LEU   A 1 175 ? 37.75454 0.54329   7.43392  1.000 44.78254  ? 172 LEU   A HD22 1 
ATOM   2658 H HD23 . LEU   A 1 175 ? 36.86997 1.64796   6.71229  1.000 44.78254  ? 172 LEU   A HD23 1 
ATOM   2659 N N    . ASN   A 1 176 ? 41.47490 4.14773   5.30202  1.000 32.19553  ? 173 ASN   A N    1 
ATOM   2660 C CA   . ASN   A 1 176 ? 41.67175 5.57000   5.08444  1.000 24.72625  ? 173 ASN   A CA   1 
ATOM   2661 C C    . ASN   A 1 176 ? 43.12821 5.97215   4.96819  1.000 33.16270  ? 173 ASN   A C    1 
ATOM   2662 O O    . ASN   A 1 176 ? 43.40215 7.14559   4.69725  1.000 30.52502  ? 173 ASN   A O    1 
ATOM   2663 C CB   . ASN   A 1 176 ? 41.04080 6.38056   6.23314  1.000 26.69090  ? 173 ASN   A CB   1 
ATOM   2664 C CG   . ASN   A 1 176 ? 39.54482 6.17823   6.33149  1.000 40.92886  ? 173 ASN   A CG   1 
ATOM   2665 O OD1  . ASN   A 1 176 ? 38.99859 6.06928   7.42378  1.000 71.10004  ? 173 ASN   A OD1  1 
ATOM   2666 N ND2  . ASN   A 1 176 ? 38.87760 6.12790   5.19140  1.000 42.52593  ? 173 ASN   A ND2  1 
ATOM   2667 H H    . ASN   A 1 176 ? 41.75191 3.86906   6.06701  1.000 38.65329  ? 173 ASN   A H    1 
ATOM   2668 H HA   . ASN   A 1 176 ? 41.22496 5.80923   4.25737  1.000 29.69016  ? 173 ASN   A HA   1 
ATOM   2669 H HB2  . ASN   A 1 176 ? 41.43801 6.10204   7.07311  1.000 32.04773  ? 173 ASN   A HB2  1 
ATOM   2670 H HB3  . ASN   A 1 176 ? 41.20767 7.32440   6.08406  1.000 32.04773  ? 173 ASN   A HB3  1 
ATOM   2671 H HD21 . ASN   A 1 176 ? 38.02515 6.01432   5.19672  1.000 51.04977  ? 173 ASN   A HD21 1 
ATOM   2672 H HD22 . ASN   A 1 176 ? 39.29598 6.20873   4.44439  1.000 51.04977  ? 173 ASN   A HD22 1 
ATOM   2673 N N    . GLY   A 1 177 ? 44.06052 5.06276   5.18529  1.000 28.97709  ? 174 GLY   A N    1 
ATOM   2674 C CA   . GLY   A 1 177 ? 45.45813 5.37575   4.99396  1.000 35.34342  ? 174 GLY   A CA   1 
ATOM   2675 C C    . GLY   A 1 177 ? 46.15170 5.79372   6.27963  1.000 40.30293  ? 174 GLY   A C    1 
ATOM   2676 O O    . GLY   A 1 177 ? 45.53584 6.08564   7.30787  1.000 31.53825  ? 174 GLY   A O    1 
ATOM   2677 H H    . GLY   A 1 177 ? 43.90592 4.25733   5.44410  1.000 34.79116  ? 174 GLY   A H    1 
ATOM   2678 H HA2  . GLY   A 1 177 ? 45.91474 4.59534   4.64273  1.000 42.43076  ? 174 GLY   A HA2  1 
ATOM   2679 H HA3  . GLY   A 1 177 ? 45.53806 6.10213   4.35609  1.000 42.43076  ? 174 GLY   A HA3  1 
ATOM   2680 N N    . LYS   A 1 178 ? 47.48010 5.84442   6.18189  1.000 31.92144  ? 175 LYS   A N    1 
ATOM   2681 C CA   . LYS   A 1 178 ? 48.33204 5.96979   7.36015  1.000 36.16663  ? 175 LYS   A CA   1 
ATOM   2682 C C    . LYS   A 1 178 ? 48.20800 7.33618   8.02079  1.000 47.85963  ? 175 LYS   A C    1 
ATOM   2683 O O    . LYS   A 1 178 ? 48.30505 7.43544   9.25249  1.000 37.18387  ? 175 LYS   A O    1 
ATOM   2684 C CB   . LYS   A 1 178 ? 49.78495 5.68616   6.95008  1.000 35.60183  ? 175 LYS   A CB   1 
ATOM   2685 C CG   . LYS   A 1 178 ? 50.83001 5.77193   8.05819  1.000 103.25417 ? 175 LYS   A CG   1 
ATOM   2686 C CD   . LYS   A 1 178 ? 51.65993 7.05850   7.95470  1.000 140.04206 ? 175 LYS   A CD   1 
ATOM   2687 C CE   . LYS   A 1 178 ? 52.97301 6.96027   8.72780  1.000 122.98802 ? 175 LYS   A CE   1 
ATOM   2688 N NZ   . LYS   A 1 178 ? 53.99292 6.15134   7.99606  1.000 129.83070 ? 175 LYS   A NZ   1 
ATOM   2689 H H    . LYS   A 1 178 ? 47.91497 5.80797   5.44084  1.000 38.32438  ? 175 LYS   A H    1 
ATOM   2690 H HA   . LYS   A 1 178 ? 48.06260 5.31632   8.02444  1.000 43.41861  ? 175 LYS   A HA   1 
ATOM   2691 H HB2  . LYS   A 1 178 ? 49.82632 4.78715   6.58820  1.000 42.74085  ? 175 LYS   A HB2  1 
ATOM   2692 H HB3  . LYS   A 1 178 ? 50.03753 6.32965   6.26962  1.000 42.74085  ? 175 LYS   A HB3  1 
ATOM   2693 H HG2  . LYS   A 1 178 ? 50.38500 5.76537   8.92006  1.000 123.92366 ? 175 LYS   A HG2  1 
ATOM   2694 H HG3  . LYS   A 1 178 ? 51.43257 5.01483   7.99017  1.000 123.92366 ? 175 LYS   A HG3  1 
ATOM   2695 H HD2  . LYS   A 1 178 ? 51.86985 7.22842   7.02306  1.000 168.06912 ? 175 LYS   A HD2  1 
ATOM   2696 H HD3  . LYS   A 1 178 ? 51.14895 7.79775   8.31982  1.000 168.06912 ? 175 LYS   A HD3  1 
ATOM   2697 H HE2  . LYS   A 1 178 ? 53.33213 7.85133   8.86178  1.000 147.60428 ? 175 LYS   A HE2  1 
ATOM   2698 H HE3  . LYS   A 1 178 ? 52.80814 6.53672   9.58473  1.000 147.60428 ? 175 LYS   A HE3  1 
ATOM   2699 H HZ1  . LYS   A 1 178 ? 54.75279 6.12881   8.45887  1.000 155.81550 ? 175 LYS   A HZ1  1 
ATOM   2700 H HZ2  . LYS   A 1 178 ? 53.69815 5.31907   7.88407  1.000 155.81550 ? 175 LYS   A HZ2  1 
ATOM   2701 H HZ3  . LYS   A 1 178 ? 54.15151 6.51146   7.19778  1.000 155.81550 ? 175 LYS   A HZ3  1 
ATOM   2702 N N    . GLU   A 1 179 ? 47.98528 8.39431   7.24070  1.000 32.48717  ? 176 GLU   A N    1 
ATOM   2703 C CA   A GLU   A 1 179 ? 47.95165 9.73317   7.82016  0.462 34.44671  ? 176 GLU   A CA   1 
ATOM   2704 C CA   B GLU   A 1 179 ? 47.95112 9.73360   7.82038  0.538 34.40596  ? 176 GLU   A CA   1 
ATOM   2705 C C    . GLU   A 1 179 ? 46.69916 9.93470   8.66364  1.000 25.17681  ? 176 GLU   A C    1 
ATOM   2706 O O    . GLU   A 1 179 ? 46.76136 10.53044  9.73965  1.000 27.13555  ? 176 GLU   A O    1 
ATOM   2707 C CB   A GLU   A 1 179 ? 48.04736 10.77843  6.70772  0.462 43.07605  ? 176 GLU   A CB   1 
ATOM   2708 C CB   B GLU   A 1 179 ? 48.02711 10.79808  6.72406  0.538 43.06184  ? 176 GLU   A CB   1 
ATOM   2709 C CG   A GLU   A 1 179 ? 49.37368 10.73222  5.94229  0.462 61.03706  ? 176 GLU   A CG   1 
ATOM   2710 C CG   B GLU   A 1 179 ? 48.13681 12.22815  7.26295  0.538 51.23206  ? 176 GLU   A CG   1 
ATOM   2711 C CD   A GLU   A 1 179 ? 49.35448 11.54341  4.65424  0.462 83.43682  ? 176 GLU   A CD   1 
ATOM   2712 C CD   B GLU   A 1 179 ? 48.23710 13.28173  6.16530  0.538 84.08517  ? 176 GLU   A CD   1 
ATOM   2713 O OE1  A GLU   A 1 179 ? 48.71028 12.61486  4.62451  0.462 87.86253  ? 176 GLU   A OE1  1 
ATOM   2714 O OE1  B GLU   A 1 179 ? 47.63770 13.09137  5.08495  0.538 81.30691  ? 176 GLU   A OE1  1 
ATOM   2715 O OE2  A GLU   A 1 179 ? 49.98335 11.10290  3.66693  0.462 66.23082  ? 176 GLU   A OE2  1 
ATOM   2716 O OE2  B GLU   A 1 179 ? 48.92030 14.30500  6.38406  0.538 74.82909  ? 176 GLU   A OE2  1 
ATOM   2717 H H    A GLU   A 1 179 ? 47.85357 8.36401   6.39139  0.462 39.00326  ? 176 GLU   A H    1 
ATOM   2718 H H    B GLU   A 1 179 ? 47.85385 8.36402   6.39134  0.538 39.00326  ? 176 GLU   A H    1 
ATOM   2719 H HA   A GLU   A 1 179 ? 48.71778 9.85148   8.40321  0.462 41.35470  ? 176 GLU   A HA   1 
ATOM   2720 H HA   B GLU   A 1 179 ? 48.72834 9.83926   8.39104  0.538 41.30581  ? 176 GLU   A HA   1 
ATOM   2721 H HB2  A GLU   A 1 179 ? 47.33110 10.62546  6.07173  0.462 51.70992  ? 176 GLU   A HB2  1 
ATOM   2722 H HB2  B GLU   A 1 179 ? 48.80897 10.62675  6.17611  0.538 51.69287  ? 176 GLU   A HB2  1 
ATOM   2723 H HB3  A GLU   A 1 179 ? 47.96027 11.66156  7.09939  0.462 51.70992  ? 176 GLU   A HB3  1 
ATOM   2724 H HB3  B GLU   A 1 179 ? 47.22431 10.74604  6.18211  0.538 51.69287  ? 176 GLU   A HB3  1 
ATOM   2725 H HG2  A GLU   A 1 179 ? 50.07556 11.08949  6.50853  0.462 73.26312  ? 176 GLU   A HG2  1 
ATOM   2726 H HG2  B GLU   A 1 179 ? 47.34869 12.42504  7.79305  0.538 61.49713  ? 176 GLU   A HG2  1 
ATOM   2727 H HG3  A GLU   A 1 179 ? 49.57072 9.81106   5.71093  0.462 73.26312  ? 176 GLU   A HG3  1 
ATOM   2728 H HG3  B GLU   A 1 179 ? 48.93244 12.29578  7.81368  0.538 61.49713  ? 176 GLU   A HG3  1 
ATOM   2729 N N    . VAL   A 1 180 ? 45.55230 9.44341   8.19809  1.000 27.34603  ? 177 VAL   A N    1 
ATOM   2730 C CA   . VAL   A 1 180 ? 44.34234 9.53976   9.01024  1.000 27.84124  ? 177 VAL   A CA   1 
ATOM   2731 C C    . VAL   A 1 180 ? 44.50631 8.76018   10.31148 1.000 24.26260  ? 177 VAL   A C    1 
ATOM   2732 O O    . VAL   A 1 180 ? 44.12013 9.23277   11.39014 1.000 24.36631  ? 177 VAL   A O    1 
ATOM   2733 C CB   . VAL   A 1 180 ? 43.12588 9.05632   8.20581  1.000 31.12295  ? 177 VAL   A CB   1 
ATOM   2734 C CG1  . VAL   A 1 180 ? 41.92225 8.91303   9.10640  1.000 28.85985  ? 177 VAL   A CG1  1 
ATOM   2735 C CG2  . VAL   A 1 180 ? 42.82979 10.04278  7.09184  1.000 33.51339  ? 177 VAL   A CG2  1 
ATOM   2736 H H    . VAL   A 1 180 ? 45.45019 9.05948   7.43535  1.000 32.83389  ? 177 VAL   A H    1 
ATOM   2737 H HA   . VAL   A 1 180 ? 44.19859 10.47074  9.24157  1.000 33.42815  ? 177 VAL   A HA   1 
ATOM   2738 H HB   . VAL   A 1 180 ? 43.31999 8.18846   7.81845  1.000 37.36619  ? 177 VAL   A HB   1 
ATOM   2739 H HG11 . VAL   A 1 180 ? 41.12322 8.85778   8.55924  1.000 34.65047  ? 177 VAL   A HG11 1 
ATOM   2740 H HG12 . VAL   A 1 180 ? 42.01770 8.10532   9.63498  1.000 34.65047  ? 177 VAL   A HG12 1 
ATOM   2741 H HG13 . VAL   A 1 180 ? 41.87070 9.68610   9.69002  1.000 34.65047  ? 177 VAL   A HG13 1 
ATOM   2742 H HG21 . VAL   A 1 180 ? 42.08134 9.71412   6.56964  1.000 40.23472  ? 177 VAL   A HG21 1 
ATOM   2743 H HG22 . VAL   A 1 180 ? 42.60854 10.90279  7.48212  1.000 40.23472  ? 177 VAL   A HG22 1 
ATOM   2744 H HG23 . VAL   A 1 180 ? 43.61462 10.12743  6.52811  1.000 40.23472  ? 177 VAL   A HG23 1 
ATOM   2745 N N    . ALA   A 1 181 ? 45.07714 7.55945   10.23728 1.000 25.12296  ? 178 ALA   A N    1 
ATOM   2746 C CA   . ALA   A 1 181 ? 45.25090 6.75456   11.44050 1.000 25.72442  ? 178 ALA   A CA   1 
ATOM   2747 C C    . ALA   A 1 181 ? 46.14166 7.46892   12.44914 1.000 24.31832  ? 178 ALA   A C    1 
ATOM   2748 O O    . ALA   A 1 181 ? 45.89786 7.40552   13.66338 1.000 30.39587  ? 178 ALA   A O    1 
ATOM   2749 C CB   . ALA   A 1 181 ? 45.83844 5.38996   11.08545 1.000 31.49434  ? 178 ALA   A CB   1 
ATOM   2750 H H    . ALA   A 1 181 ? 45.36736 7.19443   9.51469  1.000 30.16620  ? 178 ALA   A H    1 
ATOM   2751 H HA   . ALA   A 1 181 ? 44.38208 6.60886   11.84649 1.000 30.88796  ? 178 ALA   A HA   1 
ATOM   2752 H HB1  . ALA   A 1 181 ? 45.98127 4.88560   11.90161 1.000 37.81187  ? 178 ALA   A HB1  1 
ATOM   2753 H HB2  . ALA   A 1 181 ? 45.21628 4.91836   10.50977 1.000 37.81187  ? 178 ALA   A HB2  1 
ATOM   2754 H HB3  . ALA   A 1 181 ? 46.68216 5.51959   10.62477 1.000 37.81187  ? 178 ALA   A HB3  1 
ATOM   2755 N N    . ALA   A 1 182 ? 47.19139 8.14033   11.96193 1.000 28.64524  ? 179 ALA   A N    1 
ATOM   2756 C CA   . ALA   A 1 182 ? 48.08229 8.86462   12.85281 1.000 29.25323  ? 179 ALA   A CA   1 
ATOM   2757 C C    . ALA   A 1 182 ? 47.38162 10.06722  13.46014 1.000 29.57215  ? 179 ALA   A C    1 
ATOM   2758 O O    . ALA   A 1 182 ? 47.59539 10.38636  14.63623 1.000 24.05041  ? 179 ALA   A O    1 
ATOM   2759 C CB   . ALA   A 1 182 ? 49.33925 9.30889   12.10873 1.000 28.84716  ? 179 ALA   A CB   1 
ATOM   2760 H H    . ALA   A 1 182 ? 47.40190 8.18797   11.12945 1.000 34.39294  ? 179 ALA   A H    1 
ATOM   2761 H HA   . ALA   A 1 182 ? 48.35456 8.26854   13.56797 1.000 35.12253  ? 179 ALA   A HA   1 
ATOM   2762 H HB1  . ALA   A 1 182 ? 49.91240 9.79700   12.72041 1.000 34.63525  ? 179 ALA   A HB1  1 
ATOM   2763 H HB2  . ALA   A 1 182 ? 49.80283 8.52466   11.77561 1.000 34.63525  ? 179 ALA   A HB2  1 
ATOM   2764 H HB3  . ALA   A 1 182 ? 49.08251 9.88071   11.36846 1.000 34.63525  ? 179 ALA   A HB3  1 
ATOM   2765 N N    . GLN   A 1 183 ? 46.55175 10.75468  12.66937 1.000 25.37509  ? 180 GLN   A N    1 
ATOM   2766 C CA   A GLN   A 1 183 ? 45.81019 11.90861  13.17289 0.557 26.73613  ? 180 GLN   A CA   1 
ATOM   2767 C CA   B GLN   A 1 183 ? 45.85377 11.91161  13.21459 0.443 26.81885  ? 180 GLN   A CA   1 
ATOM   2768 C C    . GLN   A 1 183 ? 44.81948 11.49017  14.25221 1.000 23.00795  ? 180 GLN   A C    1 
ATOM   2769 O O    . GLN   A 1 183 ? 44.67354 12.15730  15.28239 1.000 24.62928  ? 180 GLN   A O    1 
ATOM   2770 C CB   A GLN   A 1 183 ? 45.06324 12.59885  12.02441 0.557 32.94868  ? 180 GLN   A CB   1 
ATOM   2771 C CB   B GLN   A 1 183 ? 45.21666 12.72188  12.09093 0.443 34.39214  ? 180 GLN   A CB   1 
ATOM   2772 C CG   A GLN   A 1 183 ? 45.94596 13.24507  10.96082 0.557 40.97384  ? 180 GLN   A CG   1 
ATOM   2773 C CG   B GLN   A 1 183 ? 46.23084 13.55004  11.31250 0.443 27.11846  ? 180 GLN   A CG   1 
ATOM   2774 C CD   A GLN   A 1 183 ? 45.17741 13.64117  9.68812  0.557 39.45053  ? 180 GLN   A CD   1 
ATOM   2775 C CD   B GLN   A 1 183 ? 46.99495 14.53294  12.18738 0.443 40.69248  ? 180 GLN   A CD   1 
ATOM   2776 O OE1  A GLN   A 1 183 ? 44.00749 13.28584  9.50298  0.557 30.01158  ? 180 GLN   A OE1  1 
ATOM   2777 O OE1  B GLN   A 1 183 ? 46.40405 15.29769  12.95191 0.443 31.75221  ? 180 GLN   A OE1  1 
ATOM   2778 N NE2  A GLN   A 1 183 ? 45.84444 14.38505  8.80956  0.557 41.64051  ? 180 GLN   A NE2  1 
ATOM   2779 N NE2  B GLN   A 1 183 ? 48.31895 14.50317  12.08698 0.443 37.22877  ? 180 GLN   A NE2  1 
ATOM   2780 H H    A GLN   A 1 183 ? 46.40205 10.57341  11.84213 0.557 30.46876  ? 180 GLN   A H    1 
ATOM   2781 H H    B GLN   A 1 183 ? 46.38409 10.57579  11.84506 0.443 30.46876  ? 180 GLN   A H    1 
ATOM   2782 H HA   A GLN   A 1 183 ? 46.44037 12.54021  13.55348 0.557 32.10201  ? 180 GLN   A HA   1 
ATOM   2783 H HA   B GLN   A 1 183 ? 46.49554 12.48882  13.65716 0.443 32.20128  ? 180 GLN   A HA   1 
ATOM   2784 H HB2  A GLN   A 1 183 ? 44.51131 11.93745  11.57852 0.557 39.55707  ? 180 GLN   A HB2  1 
ATOM   2785 H HB2  B GLN   A 1 183 ? 44.78473 12.11475  11.46985 0.443 41.28923  ? 180 GLN   A HB2  1 
ATOM   2786 H HB3  A GLN   A 1 183 ? 44.50528 13.29778  12.40002 0.557 39.55707  ? 180 GLN   A HB3  1 
ATOM   2787 H HB3  B GLN   A 1 183 ? 44.56221 13.32849  12.47122 0.443 41.28923  ? 180 GLN   A HB3  1 
ATOM   2788 H HG2  A GLN   A 1 183 ? 46.34445 14.04880  11.32978 0.557 49.18727  ? 180 GLN   A HG2  1 
ATOM   2789 H HG2  B GLN   A 1 183 ? 46.87521 12.95322  10.90080 0.443 32.56081  ? 180 GLN   A HG2  1 
ATOM   2790 H HG3  A GLN   A 1 183 ? 46.64026 12.61756  10.70570 0.557 49.18727  ? 180 GLN   A HG3  1 
ATOM   2791 H HG3  B GLN   A 1 183 ? 45.76518 14.05761  10.62954 0.443 32.56081  ? 180 GLN   A HG3  1 
ATOM   2792 H HE21 A GLN   A 1 183 ? 46.65705 14.61586  8.97077  0.557 49.98727  ? 180 GLN   A HE21 1 
ATOM   2793 H HE21 B GLN   A 1 183 ? 48.69704 13.94876  11.54913 0.443 44.69318  ? 180 GLN   A HE21 1 
ATOM   2794 H HE22 A GLN   A 1 183 ? 45.46299 14.63508  8.08046  0.557 49.98727  ? 180 GLN   A HE22 1 
ATOM   2795 H HE22 B GLN   A 1 183 ? 48.79819 15.03829  12.55983 0.443 44.69318  ? 180 GLN   A HE22 1 
ATOM   2796 N N    . VAL   A 1 184 ? 44.11166 10.38531  14.01211 1.000 22.77691  ? 181 VAL   A N    1 
ATOM   2797 C CA   . VAL   A 1 184 ? 43.14194 9.87997   14.97802 1.000 27.44590  ? 181 VAL   A CA   1 
ATOM   2798 C C    . VAL   A 1 184 ? 43.85153 9.36550   16.22165 1.000 21.51412  ? 181 VAL   A C    1 
ATOM   2799 O O    . VAL   A 1 184 ? 43.33346 9.48112   17.33759 1.000 24.34056  ? 181 VAL   A O    1 
ATOM   2800 C CB   . VAL   A 1 184 ? 42.28779 8.78088   14.31075 1.000 21.71123  ? 181 VAL   A CB   1 
ATOM   2801 C CG1  . VAL   A 1 184 ? 41.54839 7.96342   15.34618 1.000 28.63240  ? 181 VAL   A CG1  1 
ATOM   2802 C CG2  . VAL   A 1 184 ? 41.30983 9.39789   13.33086 1.000 35.88721  ? 181 VAL   A CG2  1 
ATOM   2803 H H    . VAL   A 1 184 ? 44.17479 9.91081   13.29764 1.000 27.35094  ? 181 VAL   A H    1 
ATOM   2804 H HA   . VAL   A 1 184 ? 42.55397 10.60025  15.25442 1.000 32.95373  ? 181 VAL   A HA   1 
ATOM   2805 H HB   . VAL   A 1 184 ? 42.87862 8.18351   13.82602 1.000 26.07213  ? 181 VAL   A HB   1 
ATOM   2806 H HG11 . VAL   A 1 184 ? 40.81157 7.50145   14.91655 1.000 34.37754  ? 181 VAL   A HG11 1 
ATOM   2807 H HG12 . VAL   A 1 184 ? 42.16024 7.31955   15.73602 1.000 34.37754  ? 181 VAL   A HG12 1 
ATOM   2808 H HG13 . VAL   A 1 184 ? 41.21016 8.55715   16.03464 1.000 34.37754  ? 181 VAL   A HG13 1 
ATOM   2809 H HG21 . VAL   A 1 184 ? 40.78386 8.69227   12.92300 1.000 43.08331  ? 181 VAL   A HG21 1 
ATOM   2810 H HG22 . VAL   A 1 184 ? 40.72831 10.01012  13.80827 1.000 43.08331  ? 181 VAL   A HG22 1 
ATOM   2811 H HG23 . VAL   A 1 184 ? 41.80603 9.87697   12.64882 1.000 43.08331  ? 181 VAL   A HG23 1 
ATOM   2812 N N    . LYS   A 1 185 ? 45.04985 8.80497   16.05688 1.000 22.84646  ? 182 LYS   A N    1 
ATOM   2813 C CA   . LYS   A 1 185 ? 45.74468 8.20124   17.18533 1.000 23.58541  ? 182 LYS   A CA   1 
ATOM   2814 C C    . LYS   A 1 185 ? 46.17298 9.23298   18.22580 1.000 26.27768  ? 182 LYS   A C    1 
ATOM   2815 O O    . LYS   A 1 185 ? 46.09098 8.97089   19.43009 1.000 23.92161  ? 182 LYS   A O    1 
ATOM   2816 C CB   . LYS   A 1 185 ? 46.95435 7.43732   16.65738 1.000 18.93687  ? 182 LYS   A CB   1 
ATOM   2817 C CG   . LYS   A 1 185 ? 47.89682 6.96965   17.73003 1.000 27.89014  ? 182 LYS   A CG   1 
ATOM   2818 C CD   . LYS   A 1 185 ? 48.99752 6.12334   17.11244 1.000 33.22830  ? 182 LYS   A CD   1 
ATOM   2819 C CE   . LYS   A 1 185 ? 49.88076 5.53186   18.18148 1.000 61.64125  ? 182 LYS   A CE   1 
ATOM   2820 N NZ   . LYS   A 1 185 ? 50.92363 4.65876   17.58560 1.000 55.68596  ? 182 LYS   A NZ   1 
ATOM   2821 N N    . ALA   A 1 186 ? 46.62355 10.40492  17.79198 1.000 22.15781  ? 183 ALA   A N    1 
ATOM   2822 C CA   . ALA   A 1 186 ? 47.30333 11.31741  18.70645 1.000 23.88037  ? 183 ALA   A CA   1 
ATOM   2823 C C    . ALA   A 1 186 ? 46.45722 11.75054  19.90051 1.000 25.77044  ? 183 ALA   A C    1 
ATOM   2824 O O    . ALA   A 1 186 ? 46.97245 11.71843  21.03121 1.000 33.06483  ? 183 ALA   A O    1 
ATOM   2825 C CB   . ALA   A 1 186 ? 47.80067 12.54094  17.92531 1.000 26.28534  ? 183 ALA   A CB   1 
ATOM   2826 H H    . ALA   A 1 186 ? 46.55054 10.69338  16.98510 1.000 26.60803  ? 183 ALA   A H    1 
ATOM   2827 H HA   . ALA   A 1 186 ? 48.06309 10.83116  19.06315 1.000 28.67510  ? 183 ALA   A HA   1 
ATOM   2828 H HB1  . ALA   A 1 186 ? 48.21667 13.16234  18.54313 1.000 31.56106  ? 183 ALA   A HB1  1 
ATOM   2829 H HB2  . ALA   A 1 186 ? 48.44679 12.25114  17.26240 1.000 31.56106  ? 183 ALA   A HB2  1 
ATOM   2830 H HB3  . ALA   A 1 186 ? 47.04561 12.96477  17.48810 1.000 31.56106  ? 183 ALA   A HB3  1 
ATOM   2831 N N    . PRO   A 1 187 ? 45.19527 12.16423  19.74473 1.000 24.48079  ? 184 PRO   A N    1 
ATOM   2832 C CA   . PRO   A 1 187 ? 44.40824 12.57987  20.91925 1.000 29.14618  ? 184 PRO   A CA   1 
ATOM   2833 C C    . PRO   A 1 187 ? 44.05381 11.44145  21.87299 1.000 27.96145  ? 184 PRO   A C    1 
ATOM   2834 O O    . PRO   A 1 187 ? 43.47651 11.70483  22.93786 1.000 24.49135  ? 184 PRO   A O    1 
ATOM   2835 C CB   . PRO   A 1 187 ? 43.13655 13.18683  20.29516 1.000 25.25434  ? 184 PRO   A CB   1 
ATOM   2836 C CG   . PRO   A 1 187 ? 43.44465 13.39935  18.85121 1.000 34.05251  ? 184 PRO   A CG   1 
ATOM   2837 C CD   . PRO   A 1 187 ? 44.43712 12.33037  18.48961 1.000 25.53837  ? 184 PRO   A CD   1 
ATOM   2838 H HA   . PRO   A 1 187 ? 44.88990 13.26524  21.40830 1.000 34.99407  ? 184 PRO   A HA   1 
ATOM   2839 H HB2  . PRO   A 1 187 ? 42.39570 12.56965  20.40061 1.000 30.32387  ? 184 PRO   A HB2  1 
ATOM   2840 H HB3  . PRO   A 1 187 ? 42.93091 14.02934  20.72965 1.000 30.32387  ? 184 PRO   A HB3  1 
ATOM   2841 H HG2  . PRO   A 1 187 ? 42.63428 13.30927  18.32578 1.000 40.88167  ? 184 PRO   A HG2  1 
ATOM   2842 H HG3  . PRO   A 1 187 ? 43.82660 14.28177  18.72332 1.000 40.88167  ? 184 PRO   A HG3  1 
ATOM   2843 H HD2  . PRO   A 1 187 ? 43.98799 11.50703  18.24201 1.000 30.66469  ? 184 PRO   A HD2  1 
ATOM   2844 H HD3  . PRO   A 1 187 ? 45.01645 12.62209  17.76838 1.000 30.66469  ? 184 PRO   A HD3  1 
ATOM   2845 N N    . LEU   A 1 188 ? 44.37002 10.19604  21.53864 1.000 22.50893  ? 185 LEU   A N    1 
ATOM   2846 C CA   . LEU   A 1 188 ? 43.95691 9.08053   22.37928 1.000 26.04515  ? 185 LEU   A CA   1 
ATOM   2847 C C    . LEU   A 1 188 ? 44.87944 8.86527   23.57295 1.000 28.43352  ? 185 LEU   A C    1 
ATOM   2848 O O    . LEU   A 1 188 ? 44.47621 8.21325   24.53825 1.000 21.85739  ? 185 LEU   A O    1 
ATOM   2849 C CB   . LEU   A 1 188 ? 43.90574 7.79101   21.56382 1.000 27.79292  ? 185 LEU   A CB   1 
ATOM   2850 C CG   . LEU   A 1 188 ? 42.92626 7.71971   20.39866 1.000 22.08827  ? 185 LEU   A CG   1 
ATOM   2851 C CD1  . LEU   A 1 188 ? 43.10675 6.41323   19.65187 1.000 26.80297  ? 185 LEU   A CD1  1 
ATOM   2852 C CD2  . LEU   A 1 188 ? 41.50090 7.82393   20.90211 1.000 24.07021  ? 185 LEU   A CD2  1 
ATOM   2853 H H    . LEU   A 1 188 ? 44.81746 9.97311   20.83885 1.000 27.02937  ? 185 LEU   A H    1 
ATOM   2854 H HA   . LEU   A 1 188 ? 43.06533 9.27023   22.71092 1.000 31.27284  ? 185 LEU   A HA   1 
ATOM   2855 H HB2  . LEU   A 1 188 ? 44.78986 7.64115   21.19401 1.000 33.37015  ? 185 LEU   A HB2  1 
ATOM   2856 H HB3  . LEU   A 1 188 ? 43.67233 7.06930   22.16844 1.000 33.37015  ? 185 LEU   A HB3  1 
ATOM   2857 H HG   . LEU   A 1 188 ? 43.09676 8.45798   19.79303 1.000 26.52458  ? 185 LEU   A HG   1 
ATOM   2858 H HD11 . LEU   A 1 188 ? 42.50018 6.39564   18.89513 1.000 32.18221  ? 185 LEU   A HD11 1 
ATOM   2859 H HD12 . LEU   A 1 188 ? 44.02386 6.35057   19.34221 1.000 32.18221  ? 185 LEU   A HD12 1 
ATOM   2860 H HD13 . LEU   A 1 188 ? 42.90904 5.67683   20.25147 1.000 32.18221  ? 185 LEU   A HD13 1 
ATOM   2861 H HD21 . LEU   A 1 188 ? 40.89480 7.77735   20.14622 1.000 28.90291  ? 185 LEU   A HD21 1 
ATOM   2862 H HD22 . LEU   A 1 188 ? 41.32673 7.08960   21.51149 1.000 28.90291  ? 185 LEU   A HD22 1 
ATOM   2863 H HD23 . LEU   A 1 188 ? 41.38998 8.66998   21.36340 1.000 28.90291  ? 185 LEU   A HD23 1 
ATOM   2864 N N    . VAL   A 1 189 ? 46.10191 9.38555   23.51566 1.000 22.14942  ? 186 VAL   A N    1 
ATOM   2865 C CA   . VAL   A 1 189 ? 47.11638 9.20924   24.54796 1.000 24.15944  ? 186 VAL   A CA   1 
ATOM   2866 C C    . VAL   A 1 189 ? 47.47499 7.73798   24.69080 1.000 31.28831  ? 186 VAL   A C    1 
ATOM   2867 O O    . VAL   A 1 189 ? 47.54992 7.20480   25.80438 1.000 24.40761  ? 186 VAL   A O    1 
ATOM   2868 C CB   . VAL   A 1 189 ? 46.67680 9.80571   25.89635 1.000 28.86505  ? 186 VAL   A CB   1 
ATOM   2869 C CG1  . VAL   A 1 189 ? 47.89325 10.00330  26.78743 1.000 27.80456  ? 186 VAL   A CG1  1 
ATOM   2870 C CG2  . VAL   A 1 189 ? 45.96611 11.13207  25.69516 1.000 21.01633  ? 186 VAL   A CG2  1 
ATOM   2871 H H    . VAL   A 1 189 ? 46.38016 9.86632   22.85912 1.000 26.59796  ? 186 VAL   A H    1 
ATOM   2872 H HA   . VAL   A 1 189 ? 47.91376 9.68010   24.25921 1.000 29.00998  ? 186 VAL   A HA   1 
ATOM   2873 H HB   . VAL   A 1 189 ? 46.05834 9.19338   26.32466 1.000 34.65671  ? 186 VAL   A HB   1 
ATOM   2874 H HG11 . VAL   A 1 189 ? 47.62483 10.48348  27.58635 1.000 33.38413  ? 186 VAL   A HG11 1 
ATOM   2875 H HG12 . VAL   A 1 189 ? 48.25259 9.13512   27.02836 1.000 33.38413  ? 186 VAL   A HG12 1 
ATOM   2876 H HG13 . VAL   A 1 189 ? 48.56013 10.51437  26.30270 1.000 33.38413  ? 186 VAL   A HG13 1 
ATOM   2877 H HG21 . VAL   A 1 189 ? 45.80197 11.53695  26.56121 1.000 25.23825  ? 186 VAL   A HG21 1 
ATOM   2878 H HG22 . VAL   A 1 189 ? 46.52817 11.71343  25.15942 1.000 25.23825  ? 186 VAL   A HG22 1 
ATOM   2879 H HG23 . VAL   A 1 189 ? 45.12470 10.97355  25.23931 1.000 25.23825  ? 186 VAL   A HG23 1 
ATOM   2880 N N    . LEU   A 1 190 ? 47.71052 7.08235   23.55878 1.000 28.01808  ? 187 LEU   A N    1 
ATOM   2881 C CA   . LEU   A 1 190 ? 48.28884 5.74480   23.53864 1.000 31.63604  ? 187 LEU   A CA   1 
ATOM   2882 C C    . LEU   A 1 190 ? 49.78524 5.80764   23.82710 1.000 32.66106  ? 187 LEU   A C    1 
ATOM   2883 O O    . LEU   A 1 190 ? 50.46248 6.77952   23.48016 1.000 46.24772  ? 187 LEU   A O    1 
ATOM   2884 C CB   . LEU   A 1 190 ? 48.04944 5.08922   22.17986 1.000 27.93651  ? 187 LEU   A CB   1 
ATOM   2885 C CG   . LEU   A 1 190 ? 46.59898 4.69419   21.92247 1.000 29.74139  ? 187 LEU   A CG   1 
ATOM   2886 C CD1  . LEU   A 1 190 ? 46.43944 4.25731   20.49839 1.000 34.34622  ? 187 LEU   A CD1  1 
ATOM   2887 C CD2  . LEU   A 1 190 ? 46.19263 3.58441   22.84953 1.000 36.31131  ? 187 LEU   A CD2  1 
ATOM   2888 H H    . LEU   A 1 190 ? 47.54131 7.39590   22.77606 1.000 33.64035  ? 187 LEU   A H    1 
ATOM   2889 H HA   . LEU   A 1 190 ? 47.87093 5.19590   24.22051 1.000 37.98191  ? 187 LEU   A HA   1 
ATOM   2890 H HB2  . LEU   A 1 190 ? 48.31298 5.71253   21.48494 1.000 33.54246  ? 187 LEU   A HB2  1 
ATOM   2891 H HB3  . LEU   A 1 190 ? 48.58824 4.28446   22.12545 1.000 33.54246  ? 187 LEU   A HB3  1 
ATOM   2892 H HG   . LEU   A 1 190 ? 46.02061 5.45599   22.08389 1.000 35.70833  ? 187 LEU   A HG   1 
ATOM   2893 H HD11 . LEU   A 1 190 ? 45.52754 3.95676   20.36053 1.000 41.23412  ? 187 LEU   A HD11 1 
ATOM   2894 H HD12 . LEU   A 1 190 ? 46.63234 5.00744   19.91444 1.000 41.23412  ? 187 LEU   A HD12 1 
ATOM   2895 H HD13 . LEU   A 1 190 ? 47.05756 3.53145   20.31961 1.000 41.23412  ? 187 LEU   A HD13 1 
ATOM   2896 H HD21 . LEU   A 1 190 ? 45.32701 3.24404   22.57433 1.000 43.59222  ? 187 LEU   A HD21 1 
ATOM   2897 H HD22 . LEU   A 1 190 ? 46.85532 2.87745   22.80538 1.000 43.59222  ? 187 LEU   A HD22 1 
ATOM   2898 H HD23 . LEU   A 1 190 ? 46.13927 3.93177   23.75363 1.000 43.59222  ? 187 LEU   A HD23 1 
ATOM   2899 N N    . LYS   A 1 191 ? 50.30166 4.75228   24.46391 1.000 41.31646  ? 188 LYS   A N    1 
ATOM   2900 C CA   A LYS   A 1 191 ? 51.71598 4.72660   24.83149 0.405 64.44450  ? 188 LYS   A CA   1 
ATOM   2901 C CA   B LYS   A 1 191 ? 51.71502 4.73405   24.83156 0.595 64.69913  ? 188 LYS   A CA   1 
ATOM   2902 C C    . LYS   A 1 191 ? 52.59991 4.68189   23.59006 1.000 53.17708  ? 188 LYS   A C    1 
ATOM   2903 O O    . LYS   A 1 191 ? 53.44808 5.55903   23.37911 1.000 93.64983  ? 188 LYS   A O    1 
ATOM   2904 C CB   A LYS   A 1 191 ? 52.00321 3.52656   25.74191 0.405 57.93755  ? 188 LYS   A CB   1 
ATOM   2905 C CB   B LYS   A 1 191 ? 52.00368 3.55201   25.76613 0.595 57.62216  ? 188 LYS   A CB   1 
ATOM   2906 C CG   A LYS   A 1 191 ? 53.41992 3.48847   26.32355 0.405 72.33100  ? 188 LYS   A CG   1 
ATOM   2907 C CG   B LYS   A 1 191 ? 53.39246 3.59873   26.40489 0.595 73.11003  ? 188 LYS   A CG   1 
ATOM   2908 C CD   A LYS   A 1 191 ? 53.53309 4.31173   27.60384 0.405 69.61428  ? 188 LYS   A CD   1 
ATOM   2909 C CD   B LYS   A 1 191 ? 53.42049 3.00406   27.81504 0.595 65.05459  ? 188 LYS   A CD   1 
ATOM   2910 C CE   A LYS   A 1 191 ? 54.98478 4.48030   28.04318 0.405 72.73853  ? 188 LYS   A CE   1 
ATOM   2911 C CE   B LYS   A 1 191 ? 53.88346 1.55283   27.82683 0.595 92.96087  ? 188 LYS   A CE   1 
ATOM   2912 N NZ   A LYS   A 1 191 ? 55.11784 5.41776   29.19782 0.405 61.66666  ? 188 LYS   A NZ   1 
ATOM   2913 N NZ   B LYS   A 1 191 ? 54.59854 1.22542   29.09560 0.595 78.26690  ? 188 LYS   A NZ   1 
ATOM   2914 H H    A LYS   A 1 191 ? 49.85996 4.05000   24.69043 0.405 49.59841  ? 188 LYS   A H    1 
ATOM   2915 H H    B LYS   A 1 191 ? 49.86167 4.04859   24.68936 0.595 49.59841  ? 188 LYS   A H    1 
ATOM   2916 H HA   A LYS   A 1 191 ? 51.92435 5.53499   25.32545 0.405 77.35205  ? 188 LYS   A HA   1 
ATOM   2917 H HA   B LYS   A 1 191 ? 51.92441 5.54873   25.31462 0.595 77.65761  ? 188 LYS   A HA   1 
ATOM   2918 H HB2  A LYS   A 1 191 ? 51.38223 3.54933   26.48673 0.405 69.54372  ? 188 LYS   A HB2  1 
ATOM   2919 H HB2  B LYS   A 1 191 ? 51.34831 3.55232   26.48125 0.595 69.16524  ? 188 LYS   A HB2  1 
ATOM   2920 H HB3  A LYS   A 1 191 ? 51.87620 2.71323   25.22882 0.405 69.54372  ? 188 LYS   A HB3  1 
ATOM   2921 H HB3  B LYS   A 1 191 ? 51.93900 2.72878   25.25721 0.595 69.16524  ? 188 LYS   A HB3  1 
ATOM   2922 H HG2  A LYS   A 1 191 ? 53.65545 2.57079   26.53160 0.405 86.81585  ? 188 LYS   A HG2  1 
ATOM   2923 H HG2  B LYS   A 1 191 ? 54.01035 3.09235   25.85472 0.595 87.75069  ? 188 LYS   A HG2  1 
ATOM   2924 H HG3  A LYS   A 1 191 ? 54.04203 3.85152   25.67388 0.405 86.81585  ? 188 LYS   A HG3  1 
ATOM   2925 H HG3  B LYS   A 1 191 ? 53.68182 4.52265   26.46442 0.595 87.75069  ? 188 LYS   A HG3  1 
ATOM   2926 H HD2  A LYS   A 1 191 ? 53.15767 5.19313   27.45189 0.405 83.55579  ? 188 LYS   A HD2  1 
ATOM   2927 H HD2  B LYS   A 1 191 ? 54.03174 3.51904   28.36465 0.595 78.08417  ? 188 LYS   A HD2  1 
ATOM   2928 H HD3  A LYS   A 1 191 ? 53.05046 3.86385   28.31613 0.405 83.55579  ? 188 LYS   A HD3  1 
ATOM   2929 H HD3  B LYS   A 1 191 ? 52.52718 3.03765   28.19155 0.595 78.08417  ? 188 LYS   A HD3  1 
ATOM   2930 H HE2  A LYS   A 1 191 ? 55.33875 3.61796   28.31148 0.405 87.30489  ? 188 LYS   A HE2  1 
ATOM   2931 H HE2  B LYS   A 1 191 ? 53.11338 0.96813   27.74944 0.595 111.57170 ? 188 LYS   A HE2  1 
ATOM   2932 H HE3  A LYS   A 1 191 ? 55.50229 4.83586   27.30381 0.405 87.30489  ? 188 LYS   A HE3  1 
ATOM   2933 H HE3  B LYS   A 1 191 ? 54.49037 1.40202   27.08533 0.595 111.57170 ? 188 LYS   A HE3  1 
ATOM   2934 H HZ1  A LYS   A 1 191 ? 55.97634 5.52140   29.40840 0.405 74.01865  ? 188 LYS   A HZ1  1 
ATOM   2935 H HZ1  B LYS   A 1 191 ? 54.82578 0.36495   29.10361 0.595 93.93893  ? 188 LYS   A HZ1  1 
ATOM   2936 H HZ2  A LYS   A 1 191 ? 54.77438 6.21125   28.98682 0.405 74.01865  ? 188 LYS   A HZ2  1 
ATOM   2937 H HZ2  B LYS   A 1 191 ? 55.33549 1.71944   29.16587 0.595 93.93893  ? 188 LYS   A HZ2  1 
ATOM   2938 H HZ3  A LYS   A 1 191 ? 54.68418 5.09396   29.90435 0.405 74.01865  ? 188 LYS   A HZ3  1 
ATOM   2939 H HZ3  B LYS   A 1 191 ? 54.07180 1.39156   29.79348 0.595 93.93893  ? 188 LYS   A HZ3  1 
ATOM   2940 N N    . ASP   A 1 192 ? 52.41056 3.66768   22.75075 1.000 51.68034  ? 189 ASP   A N    1 
ATOM   2941 C CA   . ASP   A 1 192 ? 53.22582 3.52239   21.54438 1.000 98.51191  ? 189 ASP   A CA   1 
ATOM   2942 C C    . ASP   A 1 192 ? 52.37794 3.53710   20.28006 1.000 89.62735  ? 189 ASP   A C    1 
ATOM   2943 O O    . ASP   A 1 192 ? 52.53495 4.41956   19.43540 1.000 82.52253  ? 189 ASP   A O    1 
ATOM   2944 C CB   . ASP   A 1 192 ? 54.04438 2.22891   21.60933 1.000 67.90379  ? 189 ASP   A CB   1 
ATOM   2945 C CG   . ASP   A 1 192 ? 55.13699 2.28821   22.65906 1.000 113.91188 ? 189 ASP   A CG   1 
ATOM   2946 O OD1  . ASP   A 1 192 ? 55.75183 3.36881   22.81479 1.000 106.22440 ? 189 ASP   A OD1  1 
ATOM   2947 O OD2  . ASP   A 1 192 ? 55.37370 1.26277   23.33395 1.000 118.96975 ? 189 ASP   A OD2  1 
ATOM   2948 H H    . ASP   A 1 192 ? 51.81926 3.05206   22.85549 1.000 62.03506  ? 189 ASP   A H    1 
ATOM   2949 H HA   . ASP   A 1 192 ? 53.83665 4.27420   21.49375 1.000 118.23294 ? 189 ASP   A HA   1 
ATOM   2950 H HB2  . ASP   A 1 192 ? 53.45472 1.49083   21.82943 1.000 81.50320  ? 189 ASP   A HB2  1 
ATOM   2951 H HB3  . ASP   A 1 192 ? 54.46228 2.07413   20.74776 1.000 81.50320  ? 189 ASP   A HB3  1 
HETATM 2952 O O    . HOH   B 2 .   ? 50.14761 -18.03379 21.53541 1.000 35.72832  ? 301 HOH   A O    1 
HETATM 2953 O O    . HOH   B 2 .   ? 45.87402 -1.81529  21.71697 1.000 26.21841  ? 302 HOH   A O    1 
HETATM 2954 O O    . HOH   B 2 .   ? 48.33270 0.24225   11.63967 1.000 64.31488  ? 303 HOH   A O    1 
HETATM 2955 O O    . HOH   B 2 .   ? 52.34416 -20.36727 18.77431 1.000 66.62924  ? 304 HOH   A O    1 
HETATM 2956 O O    . HOH   B 2 .   ? 51.18789 9.06698   24.34316 1.000 59.47061  ? 305 HOH   A O    1 
HETATM 2957 O O    . HOH   B 2 .   ? 25.26347 1.39457   20.13004 1.000 30.95012  ? 306 HOH   A O    1 
HETATM 2958 O O    . HOH   B 2 .   ? 29.98541 -6.26654  2.72141  1.000 43.21608  ? 307 HOH   A O    1 
HETATM 2959 O O    . HOH   B 2 .   ? 38.65402 -27.86306 11.11114 1.000 41.22487  ? 308 HOH   A O    1 
HETATM 2960 O O    . HOH   B 2 .   ? 49.14510 -24.27452 8.61441  1.000 31.60708  ? 309 HOH   A O    1 
HETATM 2961 O O    . HOH   B 2 .   ? 31.51572 1.99646   0.80583  1.000 60.90614  ? 310 HOH   A O    1 
HETATM 2962 O O    . HOH   B 2 .   ? 16.88230 -2.51459  12.18834 1.000 44.10561  ? 311 HOH   A O    1 
HETATM 2963 O O    . HOH   B 2 .   ? 37.62988 -3.06808  1.72925  1.000 37.96931  ? 312 HOH   A O    1 
HETATM 2964 O O    . HOH   B 2 .   ? 45.48749 14.68299  15.59413 1.000 34.65131  ? 313 HOH   A O    1 
HETATM 2965 O O    . HOH   B 2 .   ? 25.96187 2.95528   17.81362 1.000 29.01960  ? 314 HOH   A O    1 
HETATM 2966 O O    . HOH   B 2 .   ? 49.85097 9.95992   16.01019 1.000 38.60849  ? 315 HOH   A O    1 
HETATM 2967 O O    . HOH   B 2 .   ? 48.709   -11.827   1.483    1.000 84.34968  ? 316 HOH   A O    1 
HETATM 2968 O O    A HOH   B 2 .   ? 39.10525 -29.35971 9.31664  0.702 42.57839  ? 317 HOH   A O    1 
HETATM 2969 O O    . HOH   B 2 .   ? 45.56964 8.65412   5.24496  1.000 35.92877  ? 318 HOH   A O    1 
HETATM 2970 O O    . HOH   B 2 .   ? 43.98784 -27.86256 17.15755 1.000 34.15107  ? 319 HOH   A O    1 
HETATM 2971 O O    . HOH   B 2 .   ? 38.37399 -20.52099 2.68346  1.000 35.08334  ? 320 HOH   A O    1 
HETATM 2972 O O    . HOH   B 2 .   ? 46.224   -29.963   7.559    1.000 22.58125  ? 321 HOH   A O    1 
HETATM 2973 O O    . HOH   B 2 .   ? 30.90780 8.37524   11.11645 1.000 44.54174  ? 322 HOH   A O    1 
HETATM 2974 O O    . HOH   B 2 .   ? 33.77153 -20.08674 18.29885 1.000 41.65668  ? 323 HOH   A O    1 
HETATM 2975 O O    . HOH   B 2 .   ? 23.80827 -17.93304 16.33294 1.000 39.61885  ? 324 HOH   A O    1 
HETATM 2976 O O    . HOH   B 2 .   ? 24.00726 0.09374   7.43676  1.000 47.20714  ? 325 HOH   A O    1 
HETATM 2977 O O    . HOH   B 2 .   ? 34.90784 -22.29903 15.23313 1.000 43.24447  ? 326 HOH   A O    1 
HETATM 2978 O O    . HOH   B 2 .   ? 54.87588 6.68606   21.31208 1.000 68.89820  ? 327 HOH   A O    1 
HETATM 2979 O O    . HOH   B 2 .   ? 51.01989 -11.41257 4.13987  1.000 64.71349  ? 328 HOH   A O    1 
HETATM 2980 O O    . HOH   B 2 .   ? 31.53118 -11.75254 19.24618 1.000 22.90453  ? 329 HOH   A O    1 
HETATM 2981 O O    . HOH   B 2 .   ? 46.410   -28.227   14.285   1.000 30.39440  ? 330 HOH   A O    1 
HETATM 2982 O O    . HOH   B 2 .   ? 45.16982 -12.26308 9.87164  1.000 21.19588  ? 331 HOH   A O    1 
HETATM 2983 O O    . HOH   B 2 .   ? 41.58706 -23.27692 21.87689 1.000 36.54566  ? 332 HOH   A O    1 
HETATM 2984 O O    . HOH   B 2 .   ? 17.53710 -7.60379  25.37391 1.000 65.65375  ? 333 HOH   A O    1 
HETATM 2985 O O    . HOH   B 2 .   ? 35.15218 -25.56030 9.21203  1.000 48.77632  ? 334 HOH   A O    1 
HETATM 2986 O O    . HOH   B 2 .   ? 42.38119 -24.75246 11.13509 1.000 21.96120  ? 335 HOH   A O    1 
HETATM 2987 O O    . HOH   B 2 .   ? 21.48499 -15.71050 12.80055 1.000 46.65471  ? 336 HOH   A O    1 
HETATM 2988 O O    . HOH   B 2 .   ? 20.02164 -7.88804  19.38001 1.000 37.97243  ? 337 HOH   A O    1 
HETATM 2989 O O    . HOH   B 2 .   ? 38.95311 -17.63354 26.74816 1.000 42.25696  ? 338 HOH   A O    1 
HETATM 2990 O O    . HOH   B 2 .   ? 41.57108 -18.29034 0.94481  1.000 52.59228  ? 339 HOH   A O    1 
HETATM 2991 O O    . HOH   B 2 .   ? 23.61711 -22.46578 10.99442 1.000 77.37082  ? 340 HOH   A O    1 
HETATM 2992 O O    . HOH   B 2 .   ? 54.46747 -12.56211 7.56907  1.000 52.69987  ? 341 HOH   A O    1 
HETATM 2993 O O    . HOH   B 2 .   ? 27.64449 1.85745   7.79375  1.000 38.21885  ? 342 HOH   A O    1 
HETATM 2994 O O    . HOH   B 2 .   ? 48.36595 8.48708   21.21832 1.000 29.46795  ? 343 HOH   A O    1 
HETATM 2995 O O    . HOH   B 2 .   ? 47.42116 -25.27893 18.32818 1.000 41.20689  ? 344 HOH   A O    1 
HETATM 2996 O O    . HOH   B 2 .   ? 48.26087 -20.80308 23.01669 1.000 45.93109  ? 345 HOH   A O    1 
HETATM 2997 O O    . HOH   B 2 .   ? 12.94724 0.07216   17.55831 1.000 79.40925  ? 346 HOH   A O    1 
HETATM 2998 O O    . HOH   B 2 .   ? 28.86212 -8.96022  3.05178  1.000 42.49735  ? 347 HOH   A O    1 
HETATM 2999 O O    . HOH   B 2 .   ? 31.75760 -14.46375 26.30278 1.000 22.17681  ? 348 HOH   A O    1 
HETATM 3000 O O    . HOH   B 2 .   ? 54.49166 -15.14480 15.16536 1.000 38.34400  ? 349 HOH   A O    1 
HETATM 3001 O O    . HOH   B 2 .   ? 23.22714 -6.28865  32.30448 1.000 52.92629  ? 350 HOH   A O    1 
HETATM 3002 O O    B HOH   B 2 .   ? 38.91059 -30.20442 7.54132  0.927 59.73524  ? 351 HOH   A O    1 
HETATM 3003 O O    . HOH   B 2 .   ? 50.96534 -11.55133 7.04766  1.000 46.24010  ? 352 HOH   A O    1 
HETATM 3004 O O    . HOH   B 2 .   ? 47.83154 -0.60191  14.38144 1.000 44.91949  ? 353 HOH   A O    1 
HETATM 3005 O O    . HOH   B 2 .   ? 46.36358 -2.08749  8.14158  1.000 38.14581  ? 354 HOH   A O    1 
HETATM 3006 O O    . HOH   B 2 .   ? 30.58787 -5.36063  -4.54488 1.000 65.76261  ? 355 HOH   A O    1 
HETATM 3007 O O    . HOH   B 2 .   ? 43.58379 -13.49115 2.93719  1.000 58.90444  ? 356 HOH   A O    1 
HETATM 3008 O O    . HOH   B 2 .   ? 37.72770 -26.03253 15.96011 1.000 37.69038  ? 357 HOH   A O    1 
HETATM 3009 O O    . HOH   B 2 .   ? 21.16348 -9.90356  24.99465 1.000 40.02387  ? 358 HOH   A O    1 
HETATM 3010 O O    . HOH   B 2 .   ? 21.52335 -19.70604 11.66942 1.000 50.99860  ? 359 HOH   A O    1 
HETATM 3011 O O    . HOH   B 2 .   ? 25.94087 -12.45576 27.86402 1.000 41.76093  ? 360 HOH   A O    1 
HETATM 3012 O O    . HOH   B 2 .   ? 28.40583 -13.47925 30.53487 1.000 76.28917  ? 361 HOH   A O    1 
HETATM 3013 O O    . HOH   B 2 .   ? 30.64158 -23.45495 6.35456  1.000 59.99845  ? 362 HOH   A O    1 
HETATM 3014 O O    . HOH   B 2 .   ? 35.31727 -2.40085  -0.22750 1.000 56.37198  ? 363 HOH   A O    1 
HETATM 3015 O O    . HOH   B 2 .   ? 28.54894 -23.25223 11.27544 1.000 48.35090  ? 364 HOH   A O    1 
HETATM 3016 O O    . HOH   B 2 .   ? 29.60875 -10.13883 18.50713 1.000 21.95833  ? 365 HOH   A O    1 
HETATM 3017 O O    . HOH   B 2 .   ? 31.90090 10.38694  13.16932 1.000 32.81759  ? 366 HOH   A O    1 
HETATM 3018 O O    . HOH   B 2 .   ? 14.55080 -6.24252  11.33169 1.000 57.82925  ? 367 HOH   A O    1 
HETATM 3019 O O    . HOH   B 2 .   ? 42.88685 -26.04607 3.66473  1.000 41.96012  ? 368 HOH   A O    1 
HETATM 3020 O O    . HOH   B 2 .   ? 28.76779 6.01453   12.20202 1.000 23.84271  ? 369 HOH   A O    1 
HETATM 3021 O O    . HOH   B 2 .   ? 46.05956 1.97174   3.01747  1.000 58.88111  ? 370 HOH   A O    1 
HETATM 3022 O O    . HOH   B 2 .   ? 22.12230 -9.78132  18.90018 1.000 30.48173  ? 371 HOH   A O    1 
HETATM 3023 O O    . HOH   B 2 .   ? 41.899   12.265    11.296   1.000 28.47454  ? 372 HOH   A O    1 
HETATM 3024 O O    . HOH   B 2 .   ? 53.52965 -10.25949 20.18600 1.000 65.30887  ? 373 HOH   A O    1 
HETATM 3025 O O    . HOH   B 2 .   ? 50.68245 -4.08300  16.96923 1.000 45.62364  ? 374 HOH   A O    1 
HETATM 3026 O O    . HOH   B 2 .   ? 30.29138 -11.11370 -3.42206 1.000 61.43401  ? 375 HOH   A O    1 
HETATM 3027 O O    . HOH   B 2 .   ? 34.24869 -19.50565 20.97558 1.000 54.39438  ? 376 HOH   A O    1 
HETATM 3028 O O    . HOH   B 2 .   ? 22.63743 -12.36262 19.96407 1.000 34.60165  ? 377 HOH   A O    1 
HETATM 3029 O O    . HOH   B 2 .   ? 48.18529 -2.60807  25.17453 1.000 40.25751  ? 378 HOH   A O    1 
HETATM 3030 O O    . HOH   B 2 .   ? 22.24149 2.75979   18.72134 1.000 47.31392  ? 379 HOH   A O    1 
HETATM 3031 O O    . HOH   B 2 .   ? 53.87104 -16.93439 11.83443 1.000 63.83609  ? 380 HOH   A O    1 
HETATM 3032 O O    . HOH   B 2 .   ? 44.79472 -24.15096 4.00836  1.000 28.72310  ? 381 HOH   A O    1 
HETATM 3033 O O    . HOH   B 2 .   ? 38.82915 -19.07727 0.56643  1.000 51.46752  ? 382 HOH   A O    1 
HETATM 3034 O O    . HOH   B 2 .   ? 37.69411 12.36175  23.62143 1.000 40.42460  ? 383 HOH   A O    1 
HETATM 3035 O O    . HOH   B 2 .   ? 45.97022 -1.17161  24.87156 1.000 58.32086  ? 384 HOH   A O    1 
HETATM 3036 O O    . HOH   B 2 .   ? 44.47077 -22.76817 22.70703 1.000 36.10834  ? 385 HOH   A O    1 
HETATM 3037 O O    . HOH   B 2 .   ? 14.71376 -6.55664  14.87189 1.000 77.13583  ? 386 HOH   A O    1 
HETATM 3038 O O    . HOH   B 2 .   ? 52.12633 -9.08582  22.99851 1.000 49.24419  ? 387 HOH   A O    1 
HETATM 3039 O O    . HOH   B 2 .   ? 24.66897 3.58307   11.89221 1.000 54.41126  ? 388 HOH   A O    1 
HETATM 3040 O O    . HOH   B 2 .   ? 18.82342 -9.77120  12.77206 1.000 39.39237  ? 389 HOH   A O    1 
HETATM 3041 O O    . HOH   B 2 .   ? 48.33847 8.49916   3.99577  1.000 50.60786  ? 390 HOH   A O    1 
HETATM 3042 O O    . HOH   B 2 .   ? 26.46949 -19.34942 22.70615 1.000 65.10520  ? 391 HOH   A O    1 
HETATM 3043 O O    . HOH   B 2 .   ? 51.21662 -11.27477 21.60189 1.000 42.17448  ? 392 HOH   A O    1 
HETATM 3044 O O    . HOH   B 2 .   ? 53.51310 -7.90326  17.55982 1.000 40.50663  ? 393 HOH   A O    1 
HETATM 3045 O O    . HOH   B 2 .   ? 39.82043 12.76569  22.43614 1.000 43.95436  ? 394 HOH   A O    1 
HETATM 3046 O O    . HOH   B 2 .   ? 26.35911 -12.31115 30.72175 1.000 50.66701  ? 395 HOH   A O    1 
HETATM 3047 O O    . HOH   B 2 .   ? 19.08663 -9.09014  21.81492 1.000 54.32986  ? 396 HOH   A O    1 
HETATM 3048 O O    . HOH   B 2 .   ? 51.66689 -6.50478  15.49970 1.000 45.41806  ? 397 HOH   A O    1 
HETATM 3049 O O    . HOH   B 2 .   ? 38.616   11.573    8.194    1.000 39.57953  ? 398 HOH   A O    1 
HETATM 3050 O O    . HOH   B 2 .   ? 26.89750 -15.26610 0.04546  1.000 49.03613  ? 399 HOH   A O    1 
HETATM 3051 O O    . HOH   B 2 .   ? 47.69434 0.11431   22.31236 1.000 56.56373  ? 400 HOH   A O    1 
HETATM 3052 O O    . HOH   B 2 .   ? 49.89198 5.44260   11.21496 1.000 62.75932  ? 401 HOH   A O    1 
HETATM 3053 O O    . HOH   B 2 .   ? 49.76341 10.78581  22.34430 1.000 57.16188  ? 402 HOH   A O    1 
HETATM 3054 O O    . HOH   B 2 .   ? 25.17988 -16.42803 24.55869 1.000 51.64505  ? 403 HOH   A O    1 
HETATM 3055 O O    . HOH   B 2 .   ? 41.48902 1.84544   0.75657  1.000 60.02330  ? 404 HOH   A O    1 
HETATM 3056 O O    . HOH   B 2 .   ? 40.70553 -15.30011 1.15435  1.000 49.32493  ? 405 HOH   A O    1 
HETATM 3057 O O    . HOH   B 2 .   ? 35.54700 7.52199   5.51485  1.000 52.15342  ? 406 HOH   A O    1 
HETATM 3058 O O    . HOH   B 2 .   ? 39.23199 -13.52298 -2.31700 1.000 62.92183  ? 407 HOH   A O    1 
HETATM 3059 O O    . HOH   B 2 .   ? 19.82167 2.52057   19.20764 1.000 64.00967  ? 408 HOH   A O    1 
HETATM 3060 O O    . HOH   B 2 .   ? 35.10766 -14.14911 26.97723 1.000 23.14423  ? 409 HOH   A O    1 
HETATM 3061 O O    . HOH   B 2 .   ? 53.808   -20.869   12.316   1.000 56.58382  ? 410 HOH   A O    1 
HETATM 3062 O O    . HOH   B 2 .   ? 17.06045 0.50889   12.35161 1.000 53.64822  ? 411 HOH   A O    1 
HETATM 3063 O O    . HOH   B 2 .   ? 40.92015 -28.63191 18.30404 1.000 63.10282  ? 412 HOH   A O    1 
HETATM 3064 O O    . HOH   B 2 .   ? 47.01321 -22.33270 25.20310 1.000 73.31260  ? 413 HOH   A O    1 
HETATM 3065 O O    . HOH   B 2 .   ? 38.31164 -27.60820 18.18076 1.000 55.87967  ? 414 HOH   A O    1 
HETATM 3066 O O    . HOH   B 2 .   ? 38.91721 -20.69237 26.77066 1.000 54.01813  ? 415 HOH   A O    1 
HETATM 3067 O O    . HOH   B 2 .   ? 50.56773 9.23251   18.77256 1.000 51.70538  ? 416 HOH   A O    1 
HETATM 3068 O O    . HOH   B 2 .   ? 46.97942 -9.13485  -0.69688 1.000 76.09794  ? 417 HOH   A O    1 
HETATM 3069 O O    . HOH   B 2 .   ? 20.76175 -10.91855 22.02374 1.000 61.00023  ? 418 HOH   A O    1 
HETATM 3070 O O    . HOH   B 2 .   ? 21.38999 -17.60814 25.55961 1.000 69.88448  ? 419 HOH   A O    1 
HETATM 3071 O O    . HOH   B 2 .   ? 29.14335 -3.06413  -4.90493 1.000 69.78226  ? 420 HOH   A O    1 
HETATM 3072 O O    . HOH   B 2 .   ? 44.84012 -8.87132  -1.64489 1.000 64.72401  ? 421 HOH   A O    1 
HETATM 3073 O O    . HOH   B 2 .   ? 18.731   -5.659    28.533   1.000 55.76411  ? 422 HOH   A O    1 
HETATM 3074 O O    . HOH   B 2 .   ? 49.71188 -3.04640  12.83924 1.000 55.50662  ? 423 HOH   A O    1 
HETATM 3075 O O    . HOH   B 2 .   ? 18.02738 2.13072   21.65049 1.000 76.80857  ? 424 HOH   A O    1 
# 
